TissueScope

TissueScope is a cross-species bulk RNA-seq brain atlas designed for large-scale transcriptomic comparisons across species and tissues, allowing users to explore evolutionary gene expression patterns and tissue-specific transcriptomics. It concludes 293 species spanning 147 fishes, 6 amphibians, 109 mammals, 11 reptiles, and 20 birds. . TissueScope offers key functional modules: sPandora & ePandora, allowing single-gene and gene-set expression analysis; GeneLists, providing access to differentially expressed gene lists for specific tissues; and TimeTree, which visualizes phylogenetic relationships among species for evolutionary insights.

There are five main tabs: Single-dataset exploration, sPandora, ePandora, GeneLists, TimeTree.

Single-dataset exploration

Users can explore brain bulk RNA-seq sequencing data for species of interest at Single-dataset exploration.

Users can explore the data of species of interest in two ways:

1. Filter Selection – Use the filter panel to select specific species.

2. Clicking Species Images – Click on an image of the species of interest to access its brain single-cell datasets.

When your mouse move over an image of a species of interest, a pop-up visualization will appear, displaying statistic of expressed gene categorized into various functional groups (e.g., enzymes, transcription factors, transporters).

When you choose a species of interest, there is a dataset table, which includes: Classification, Common Name & Latin Name, Tissue Source, Journal & PMID Informatin, Detail and ViewData.

Click “Detail” to view in-depth dataset metadata, including study title, journal, PMID, and more.

Click “ViewData” to enter the bulkRNA-Seq Dataset page for further exploration.