Dog: Disease Oriented Genotype-cell-type mining
Dog module is a disease-oriented gene-to-cell single-cell analysis. It provides correlations between disease-causing genes and cell type through disease enrichment analysis, which will help to localize disease-causing genes in cells.
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Dataset information

BSID: {{dataInfo.BSID}}

Classification: {{dataInfo.Classification}}

CommonName: {{dataInfo.CommonName}}

LatinName: {{dataInfo.LatinName}}

BrainRegion:{{dataInfo.Region}}

Timing:{{dataInfo.Timing}}

Diseases: {{dataInfo.Diseases}}

Tech: {{dataInfo.Diseases}}

CellNum: {{dataInfo.Tech}}

Title: {{dataInfo.Title}}

Journal: {{dataInfo.Journal}}

PMID: {{dataInfo.PMID}}

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Shinycell: View data

  • Drug2Cell
  • OmiCross
  • GOAT
  • MolFinger
  • AssocScape
Part1: PhenOmics (Clinic information)

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  • SCAR_Sample_ID
  • SCAR_Patient_ID
  • Original_Patient_ID
  • Original_Sample_ID
  • Gender
  • Age
  • Cancer_type
Part2: EpiOmics (enhancer/cis regulatory elements)
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  • vista_id
  • curation_status
  • experiments
  • backbone
  • stage
  • assembly
  • coord
  • coordinate_hg38
  • coordinate_mm10
  • Detail
Part3: TranscriptOmics (scRNAseq DEG)
CellType DEG
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    Part4: DiseaseOmics (DiseaseBioMarkers)
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    • Disease
    • MolecularType1
    • MolecularType2
    • bioMarker
    • Detail
    Part5: OneOmics (Disease single cell atlas)
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    • DimID
    • DimTitle
    • BSID
    • Detail
    Comparision across multiple cancer types
    Part6: Genomics (DEG SNP)
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    • refsnp_id
    • chr_name
    • allele
    • chrom_start
    • chrom_strand
    • Symbol
    • Celltype
    • Disease
    • Trend
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    • ID
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    • GeneList
    • Gene list
    • Toppgen enrichment
    • PPI
    • Motif Enrichment

    cluster: cellcluster; gene: gene symbol; p_val: p value; avg_log2Fc: average logfc between two groups; pct.1: the proportion of cels expressing the gene among the cels in the current cluster; pct.2: the proportion of cells expressing the gene among the cells in other clusters; p_val_ad;: adjusted p-value;

    • cluster
    • gene
    • p val
    • avg_log2FC
    • pct.1
    • pct.2
    • p_val adj
    Toppgen enrichment analysis of genelist
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      • Category
      • ID
      • Name
      • PValue
      • QValueFDRBH
      • QValueFDRBY
      • Detail

      Association heatmap of 66 human diseases and control
      Association table of 66 human diseases and control
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