| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 5.795e-82 | -187.05 | ZRANB1 (zinc finger RANBP2-type containing 1) | protein interactions | 54764 | 4147 | 1668 | 19454 | 5460 |
SMARCB1,OARD1,PTS,H1-3,PSMA2,ROCK2,PFDN1,RPS4X,RAB18,CBLL1,ABCF1,LSM14A,CDK5,AK2,MGMT,DDX1,CDC26,YWHAG,DKK1,NDUFV2,DDRGK1,RAB1B,ECHDC1,HNRNPL,SNRPD3,SUMO2,CCT7,HSP90AB1,PSME2,WDR82,NXT1,PPT1,AKR1A1,TIMM10,USP6NL,ACSS2,MRPL12,LMO3,SRSF2,PHB2,PEBP1,DDX39B,RCCD1,DDX5,MIA2,RPS26,MDH1,PSMA4,HNRNPAB,SFN,BTF3,PSMB6,ACAP2,IRF2,SURF2,CBX3,RP9,DISC1,KIF1C,TMSB10,HNRNPK,RPIA,RPL17,MYD88,PSME1,SMCHD1,EDC3,CPNE1,RPS27L,PHETA2,METAP1,ALYREF,UBE2G2,RAP1B,CDK6,MPV17,POLR1D,CD2AP,MAFG,RPS15,AIF1L,TMEM263,LSM12,ELOF1,GFM1,SNX33,MRPS16,CHRAC1,EXOSC1,SORD,SUGP1,NDUFAF2,TRIM32,CCNB1,CFL1,ST13,GORASP2,EIF4H,CDC20,PSPC1,UQCRC2,TMA7,SRP54,INTS12,CTNNA2,GDI2,POLR2D,MTMR2,SNRPE,NAA15,MACO1,LYPLA1,PPP2R1A,UFM1,DHX16,RAD21,COPS4,HNRNPA2B1,BCKDK,HECTD3,PCNA,MED4,DCAF11,VPS4A,DICER1,PDAP1,ZNF207,PPIA,SRSF10,DHX15,PSMB5,KRT8,RPLP2,PSMB7,ARMCX3,HEXB,MFAP1,MAPKAPK5,NDE1,NOP53,MRPL57,ATP6V1G1,FBXO30,NKAPD1,EXD2,PSMA3,BAX,PFDN2,HSP90AA1,AUH,TMED4,LRRC8A,PRDX2,TAB1,NDUFAF4,FAM91A1,ENO2,SNRPD2,ZMAT2,SEC61B,DAP,ACTR2,TRAPPC13,CMPK1,GBE1,SOX9,TSSC4,FARSA,NSMCE3,MRPS18C,VPS16,SFXN1,SIKE1,TCOF1,NKRF,CNN3,SMG9,ERCC3,GRSF1,CDC42SE2,THOC1,PTPN1,DECR2,CARHSP1,RARS1,SF3A1,UQCRC1,SLC35E1,CDK7,SLC7A1,RPA3,CLK1,KIN,SPCS2,AOX1,ARFGAP3,CDC73,STK38L,CIAO1,ZNF687,RACGAP1,FERMT2,FAH,POP7,F10,CMBL,SFXN2,ALB,ODR4,PIR,UCK2,SMNDC1,ZRANB2,AAMP,UBL5,MAX,SUPT5H,CRTC2,TRAF2,KRAS,RABGGTB,ACTR1B,SREK1IP1,RTCB,R3HDM4,DRG1,PPP1R11,NDUFB8,PPFIBP1,PPIB,MRPL9,IQSEC1,PAIP1,TRIR,MACROD1,FABP5,CLK4,SRSF1,MAGED2,DIPK2A,PALS2,SHMT1,SAP18,PYM1,ARRDC3,RAB5A,H1-10,ICAM1,MCAT,THOC6,COPS7A,EPS8,TCEAL1,TIMM21,SF3B4,TMEM165,ACOT13,RRM1,ZNHIT1,UBL4A,SRFBP1,CDC40,SRPRB,TMEM33,CAPZA1,TCEA2,SLC25A11,MRPS18B,RAB13,RPS2,CDK12,USP15,TCEANC2,KARS1,RBM17,PGAM1,COPS5,HP,ORMDL3,MZT2B,RPS16,ARL6IP5,RBM42,DKC1,GTF2B,COQ8A,H2BC11,RPA2,HEXIM1,HECTD1,ACACA,TRAM1,RBM22,MRPL40,EIF4E,ABCC2,UGDH,CWF19L1,EXOSC4,CCDC174,CALU,CEP85,EXOC5,CHPF,BUB3,MYG1,SRC,BCCIP,LIG3,ABHD14B,PSMC5,MOB4,MRPS28,VPS33A,RBPJ,GPBP1L1,GTPBP1,YIPF3,NUP153,RBBP7,NRGN,CBX7,ZBTB14,MCM6,HS2ST1,BLOC1S2,SRSF8,HBA1,TST,RPL23,PRPF19,TAF7,CRIP1,EIF3D,POLR3F,SNX2,CGGBP1,ERLIN1,NDUFS8,CETN2,MYEF2,PBDC1,CYB5A,COPS2,ATP5PO,RNF7,WDR77,IDH3B,PPP1CB,RAB6A,THOC3,RTKN,FBXW4,DCTN3,GNA14,RNF10,NUP50,COMMD2,BLVRA,ELMO2,LMNB1,SP1,NDUFB7,NOP16,RNF40,RBM15B,MCM4,AKR1C2,TSN,DYNLL1,UMPS,CHCHD3,SNRPB2,TNPO3,UBE2S,PIGK,APEH,MTA3,TBK1,MRPL11,DDX39A,RPL15,CTNNBL1,TF,WASL,ARF4,NSDHL,STX8,ZNF787,MPHOSPH10,CALR,GMPPA,ALCAM,PPP1R18,HACD3,SRPRA,EHBP1,SOCS4,CDCA3,JUP,LMNA,LSM2,RPLP0,RPS14,PSMC4,FAM161A,SIPA1L1,CNP,ELP3,DGCR8,NPM3,GTF2I,SGF29,MPZ,RPL4,NHP2,POLDIP2,SS18,RETREG2,ORMDL1,CHORDC1,IVNS1ABP,ATOSB,EPHA2,PNPO,CAP2,KPNA6,HYCC2,PPP1CC,RAB14,LDHA,ZNF622,SLC25A4,SMAD5,DTYMK,CHCHD6,TUBB4B,NDUFA12,HGS,TAF10,MIEF1,ETFB,DHX38,TFPI,DCTPP1,FKBP2,PRPS1,UTP25,RPL31,EWSR1,MYO1B,UBFD1,CNOT2,BAZ1B,RPL6,EXOC1,NGDN,RPS10,ISG20L2,NOB1,ZNF740,PEG10,FHIP1B,RAB35,RBM5,ACAA2,NUFIP2,CSNK1A1,TRMT112,UFL1,EEF1G,NGRN,JAGN1,TIMP3,GPHN,CIRBP,CCT2,CMC1,SERPINH1,CPSF2,UFD1,REEP3,CBX5,RPL10,FAIM,VDAC2,CMTR1,TRMT11,MCPH1,CAPZA2,STRBP,FAM162A,METTL15,NUP107,NEDD8,PDE12,H3C1,CSE1L,PHF1,MRPL52,RPL24,LSM3,MAP4,USP2,MTMR12,PPIL4,GAPDH,API5,TMED9,ESD,MRPS9,RPL32,MGME1,GATAD1,HBB,CSNK1G3,PAAF1,TDRP,TXNDC17,MECP2,IGF2BP1,CDKN2AIP,SMARCA5,AKT1,SLC25A1,MTPN,IRF2BP1,RNASEH1,IDE,ALG2,CSNK2B,PHAX,CALML5,PPP2R5E,PPID,BZW2,CHMP4C,RPS11,JPT2,HSDL2,CKS1B,FAF2,ATP5F1D,SSRP1,NEK9,SLC25A5,ZYX,SCYL2,HINT2,MRPS11,SRSF7,SKA1,ZCCHC9,SKIC8,RB1CC1,HAX1,HNRNPA1,AGK,RPL9,MRTO4,BRD9,ANXA7,SLC25A3,FKBP1A,PGRMC1,SRM,CDSN,CMAS,DNAJC3,TXNL1,EMG1,ARHGAP19,LSM14B,NFYA,CDC123,TM9SF4,PKP4,PMPCA,F2,PYCR1,MRPL16,MRPL23,PGPEP1,REEP4,ABHD12,TRMT6,POLR3B,RPS9,TNFAIP8L1,TOPORS,CCT5,TRIM62,GPAM,HUWE1,ERLEC1,FN3KRP,CDC42SE1,SMN1,TTC8,KIAA1143,PMM2,ATP5MG,SUV39H1,DCUN1D1,MRPL50,DERL2,TOMM70,NKIRAS2,CWC15,TIMM8B,PSMB1,COX6C,STOM,HAUS2,UBLCP1,MRPL17,CXXC1,PPM1G,CCHCR1,PPIG,GGCX,BAHD1,RHOBTB3,NDN,CTTNBP2NL,UBE2L3,DEK,PDCD5,VIRMA,GNAI2,MRPL53,CTTN,EIF2AK2,STMN2,CAAP1,MTA2,PPIL3,KIF2A,ZBED1,GJB1,MAPK1IP1L,VDAC1,POLDIP3,TAX1BP3,GSTM3,EIF2S1,AFTPH,LYAR,LSM5,TCP1,UQCRH,PTK7,EED,UBAC2,KLC2,NCOA5,NUP62,RPL27A,ISCU,DHRS4,EIF1B,STAU1,RPP14,RFC4,SLU7,XRCC5,HSPA8,AKAP1,YAF2,CHTOP,NSA2,HMGCS1,PSMD4,LORICRIN,EFHD2,GTF2F2,PHKB,CHAMP1,ACADSB,TAB2,TAF2,CCL20,IPO8,UBIAD1,H2AX,HADH,TCIM,ZMYM4,RBCK1,IMP4,KPNA2,NAE1,RUSF1,IDH1,TUBG1,POLB,SNRNP70,CMSS1,ACOT8,ZNF24,TMA16,CSNK2A1,SHPRH,SURF6,SLAIN2,PREP,LCMT1,CD46,VPS4B,UBE2M,PRKCA,E2F6,AKR7A2,SUMO1,CCNH,GTF3C4,TRMT13,ZC3H15,TOMM20,HSPA5,POLR1H,APMAP,POLD2,ATP1A1,SNX5,FGFR1OP2,MAT2A,GSTK1,GPX1,RALA,ADRM1,PPP1R10,CSTF3,EIF2S2,STIM1,EZH2,EIF1AX,PLD3,CYB5B,ACO1,PNMA5,WDR37,G3BP1,LAMB2,GNL1,ETFA,UNC119B,RFC3,NDUFA4,FHL3,UBE3A,ERP29,PSMD10,PDCD10,PSMD3,MMUT,RPL7,CCAR2,ZNF593,DNM2,PHB1,HP1BP3,CPLX2,PCLAF,NRDE2,TIMM29,ATAD1,POLA2,G3BP2,UNC45A,ATP5MK,TRUB1,BLOC1S5,NOA1,ALDH1L1,RFC5,SAMHD1,AK3,GALE,RFXAP,SPINDOC,RPL19,CYB5R3,EIF3K,SLC30A7,UAP1,PPME1,CCDC47,PHF23,YTHDF2,PSMB9,GGCT,POP5,POLL,HSPE1,RNF20,CTNND1,OLA1,GALNT2,ZC3H11A,RING1,HSD17B10,EMC2,ZNF575,NFKB1,HDAC6,TOP1,EIF2B5,POLR2I,MAPRE2,NOP9,G6PD,SLC25A12,AIFM1,DFFA,CTDSPL2,HSD17B11,SEC23A,CDK1,ATG16L1,WDR83,TPT1,SPR,SNRPN,EDF1,EIF3J,B2M,EIF5B,NUCKS1,CRYZ,SLC5A6,AATF,SIRT7,ITGA2,MAVS,MTDH,CCDC22,XPOT,RETSAT,ATP5F1A,TUFM,TXN,TECR,SEC63,SULT1A3,CYRIB,PRKRA,RTRAF,GAS2,ACAT1,TRIM24,PLS3,PTRH2,NCSTN,RPS7,NUP37,RUVBL1,VAMP8,TFG,GSTO1,CDC23,MAGOH,PTDSS1,RAB5C,CTNNB1,DBR1,TTC9C,SNRPA1,OSBP,TRMT61A,SIN3A,TRAM2,ANXA4,PRCC,LAP3,ZC3H14,TRA2B,GOSR1,SLC31A1,NDUFS2,ITGAV,PACSIN3,BOLA3,SPECC1L,PCGF2,ADK,CKB,KIAA1191,PSMD14,S100A11,MRPS25,COX6B1,SLC1A3,STAT1,MATR3,TAMM41,MTG1,SCNM1,SMU1,PRMT5,GUCD1,COX19,CAPN2,GNAI3,NUPR1,ATP5PB,MVD,ZNF581,ESS2,GNPNAT1,SNRNP48,MEPCE,SEPHS1,MPST,NUS1,NOL12,AKAP8L,SMG8,ENY2,USP3,GNG2,VTI1B,MIF,SLC38A2,LMAN1,UBE2N,ADD1,DSTN,MTAP,CDC42,MND1,STK38,UGP2,GRPEL1,MAIP1,RPL27,NBN,PGK1,ATP1B3,CISD1,BICD2,OAT,ALKBH5,RBM7,RAB2A,FAM193B,RPL7A,ARHGAP21,PHKA1,STAT5A,HPF1,CHMP5,RBMX2,PITPNB,SEC61A1,PTPMT1,NDUFS6,ITGB5,BUD23,NEU1,OTUD6B,ACADS,S100A10,ASF1A,GTF3C3,SACM1L,FOXP4,HSPD1,PRPSAP1,PPM1B,ATG9A,BABAM1,PRPF18,SLMAP,TMEM237,RPL8,ZNF664,USP39,LARP4B,ELOVL1,ACTL6A,GKAP1,PAFAH1B2,STX7,CSRP1,PYGB,CFDP1,DCAF4,MTG2,ACO2,PRPF31,SMARCE1,MED17,MAT2B,ERH,CLIC4,PRRC2A,USP5,NDUFS3,DHRS7B,DTD1,FAM169A,SERPINA1,NDUFA2,BLOC1S3,UBE2V1,EIF4EBP2,NOC4L,DNAAF10,VRK1,FASTKD5,VTA1,PPP1R12A,RAB1A,RPL23A,GNG5,UBXN10,OSBPL8,FNDC11,MOV10,HM13,ATP1B1,PLEKHF2,RPL35A,NCBP2,MRPL24,SMAD3,RPL12,RB1,METTL2A,DCTN4,CHMP1A,METTL14,GOLGA5,HNRNPH3,RPL26L1,PCK2,DDAH1,NF2,CHMP2B,CDC42EP4,BRIX1,ZKSCAN1,HMCES,TCEA1,RTN4,MAPRE1,HSPA14,DHPS,RPL26,FBXO7,DNAJC8,HMOX2,CTNNBIP1,COPE,RPP25L,GXYLT1,TUBA1B,METAP2,COA5,HEXIM2,RPS12,GNPDA1,METTL21A,NFKBIL1,RPL18,CRKL,RANBP1,RERE,CTTNBP2,CCT8,COA4,STAMBPL1,HSPB1,RIOX2,NT5C2,DYNC1I2,RMND1,GAMT,PIH1D1,FDFT1,GOSR2,EHHADH,CNPY3,CD59,EMC1,PRCP,MT2A,MRPS7,SNRPA,EP300,LAMTOR1,COMMD9,FTSJ3,PRSS1,POLR1B,THAP7,PCCB,COX11,CAVIN2,ATP5F1B,CYP27A1,SNRNP40,PPP5C,GLRX2,GTF2F1,TFRC,TBC1D4,SNAP29,MRPL47,MTCH2,WBP11,RPAP2,ZMYM3,CHDH,FKBP8,SNIP1,PALM2AKAP2,ATP5PF,STX18,ERO1A,LANCL2,NKAP,TMPO,EEF1B2,GLT8D1,UGT2A3,STT3A,CAMLG,COMT,TRAPPC3,RPRD1B,STX17,EIF2B3,USE1,DNAJC24,PPP1R8,CAPN1,SNRNP27,NAPG,MARS1,HNRNPH2,DNAJC10,MORF4L1,TYW3,RPS17,MRPS21,PPAT,SUCLG2,RPS3,ACOX1,GCFC2,MOXD1,CTSA,GFPT1,GTF2E2,KCTD17,SRSF4,MRPS17,GSTT1,RFC2,MORC2,PPAN,ARGLU1,DDX23,TRAF6,CLPX,WDR11,TRA2A,RBIS,KCTD10,BUD31,CACYBP,WDR6,THOC2,TRAF3IP3,APOBEC3C,ADNP,RTF2,H1-5,TIMM13,PRDX3,NFIL3,MCMBP,COIL,SKP1,ATP5IF1,CMC4,HADHA,DHRS1,CUL2,MRM2,PROX1,TTC23,RPL35,GNB1,CHP1,RAN,PELO,LRRC1,PPP4C,MRPL49,COMTD1,NECAP2,EEF1A1,ING1,LBR,PAK1IP1,CAMK2G,THRAP3,TOM1,RPS13,MSH6,PRDX4,DLG1,PC,SNAP23,PSMD7,EXOC2,AMT,GTF2E1,MPG,GLO1,EIF2B2,TSPYL4,AKAP17A,POLE3,ATP5PD,SRP14,MRPS34,ZNF574,EPHX1,MACROH2A2,CPSF4,EEF1E1,COMMD3,SMC4,PFKFB2,HMGB1,MBD3,PRPF4,ARPC2,PIP4K2C,NAPA,CASC3,CDC16,PYCR2,SNX3,DNPH1,RPL22,HYCC1,VAMP3,EIF4A3,GANAB,CFAP298,RPS20,UBE2I,PDHA1,APTX,RPS23,TRMT1L,GCLC,SNAPIN,TUBA1A,EEF2,ELF1,PSMA1,HNRNPF,CCAR1,FBXO3,TRIM21,ARHGAP5,PFDN5,XPO1,YWHAH,QPCTL,AASDHPPT,GLRX,FUBP3,MTHFS,STX5,EIF4B,CNDP2,PSMB3,HIGD2A,LYPLA2,RPS28,SF3B1,RAMAC,FBXW11,H2AZ2,RCL1,HNRNPC,RMI2,PSMD1,BAG3,DRAP1,LRIF1,POLR2B,NCKAP1,APEX1,SESTD1,DLST,MRPL13,SURF4,DDX42,MRPL33,IMP3,RPSA,GTPBP8,PSMA5,CTSC,RDH11,CLPB,DHX9,CHCHD1,TRAPPC2L,KPNA1,COX5A,ELOC,TPM3,CAND1,MYL12A,ITGA6,ACSL4,G6PC3,TFB1M,TFIP11,LUC7L3,CYC1,LEMD3,CLU,LIN7C,DDX46,PDCD4,NUDT4,CHST13,PSMB2,ALKBH2,CFL2,DAPK3,CTSB,TXNDC12,NOPCHAP1,SF3B6,MACROH2A1,EPCAM,RPN1,PRKAG1,EXOSC3,NME1,POLR2C,SART3,ANP32A,RBM12,RPL29,ACTN4,RPS27A,PSMD12,AHCYL1,SAR1B,MSL2,ENKD1,NUDT5,FAM76B,PLCB1,BAG2,CDK5RAP3,MRPS26,HNRNPD,PDIA3,HMGA1,NDC80,NUP35,PSMB4,ATP6V1A,VAPB,KLF3,VPS18,ARCN1,ASRGL1,ATAT1,CYFIP2,YTHDF1,DUSP9,BIRC2,YWHAZ,RPS5,CCDC25,SCFD1,HTRA2,ILK,ZNF250,RAB11A,RPS29,LGALS3,TUBB,RSRC1,SNRPD1,AP1G2,CD2BP2,MAP2K3,EXOSC8,FCF1,TIMM8A,CNOT7,PTGES3,PQBP1,MRFAP1,POR,NME2,FOXP1,BRD3,SPATS2L,FAM133B,CDK9,MRPS23,WDCP,EIF4E2,KRR1,ST6GAL1,DCK,TSR2,COX20,CHID1,ZCCHC17,WTAP,PDE8A,SEC22B,PIP5K1A,SYNRG,PDHB,LSM8,HELLS,DVL2,PRIM2,SOD1,IDH3A,PPIH,AP2A1,TMOD3,UQCRQ,CTNNA1,ENO1,SPIN3,FAM136A,SVBP,CCDC134,CSTF2T,CHCHD2,HMGN4,RPL28,HNRNPDL,UQCC2,NDUFB5,RBM3,RUVBL2,RPAP3,PDIA6,AGR2,FKBP4,YWHAB,POGK,CST3,TBC1D5,CBR4,FAM98A,MEAF6,SLC38A3,ZNF511,LANCL1,FBXO31,SERPINC1,POLR2L,CORO1C,S100A8,PAK2,RPP21,YIPF5,NDUFAF3,HNRNPA0,PITHD1,SSR3,PTRHD1,FAM50B,P4HA2,MRPL34,STK26,RBM27,DNAJB6,PBLD,TBCE,USP16,PSMD6,TRIM29,FBXO22,TACO1,ZNHIT6,TMEM31,DNAJC2,NHERF1,ARPC3,RBM34,IK,PSMC3,PREB,ARHGAP12,ACTR1A,TOLLIP,EIF1AD,NOSIP,ABCE1,RBM41,SLC16A1,RPL3,PSMG2,RPL10A,ILVBL,CDC5L,SDHB,AIP,SYNCRIP,NDUFB4,COQ10B,COX4I1,WRAP53,SDCBP,ZNF326,IDH2,SAMM50,GIT2,SPTBN1,NTPCR,KDM1A,UBE2K,SNAPC1,THUMPD1,BANF1,PRDX6,RNF113A,EIF3G,LSM6,NAA50,PTPN11,TIA1,GMDS,ROCK1,DUSP3,CREB1,PSMA6,PAFAH1B3,SGTA,SF3B5,FEN1,MARCKSL1,LASP1,ADO,AP1M1,ANP32B,EIF2D,HNMT,TMT1A,SLC39A7,JAK1,RPS24,GSTA2,LYZ,RSBN1L,AHSA1,NQO1,BCL2L1,PRDX1,MRPS35,FRA10AC1,STOML2,DPY30,ATG7,COPS7B,KIF3B,NOP58,ATXN10,SNX1,SPTAN1,NTMT1,OS9,LRWD1,XPO5,GATD3,RPLP1,PSRC1,FAM3C,MYL6,ZNF805,NDUFA5,MTX2,EHD1,ETF1,NSFL1C,PSMC1,UPF3B,RLIM,CCDC86,MCM8,MYO6,PFDN6,CFAP20,RIOK2,MCM3,MTM1,RBBP4,RPL7L1,MAD2L1,APOBEC3G,FAU,CPSF1,PARP2,RMDN3,ARPP19,RPL37A,AP2M1,DMAP1,ILF2,RAD23B,SRP72,AKR1C1,MLLT6,PPIF,LSM4,MRPL22,SNRPG,EIF3E,MDC1,SLC25A10,H2AC25,GLUL,SEPTIN7,HINT1,SLC2A1,ESYT1,DNAJC7,RELL1,ARF6,SSU72,TOX4,P3H1,TIMM23,HSP90B1,NOL7,MTRES1,IFRD1,SAP30BP,CRAT,CERS2,PPP1R2,TMEM209,PNO1,SLC2A3,CSTB,SQSTM1,TADA3,NDUFB10,CTSD,SEC13,NONO,USP14,GMPS,MAGOHB,RPL13A |
| 1.970e-74 | -169.71 | TRIM67 (tripartite motif containing 67) | protein interactions | 440730 | 4804 | 1851 | 19454 | 5460 |
EXOC8,WDR20,RHEB,TOMM40,CUL2,GRB10,CHP1,GNB1,GGPS1,RPL35,LRRC1,PELO,RAN,RTF2,TBC1D17,ADNP,PRDX3,H1-5,PRKAB1,SKP1,TGFB1I1,MCMBP,GPM6A,CNTN1,HADHA,TMEM168,PPP3CA,TRAF6,DDX23,TRA2A,WDR11,CLPX,SELENON,CACYBP,BUD31,ODC1,PCBP4,PPP2CB,THOC2,WDR6,CTSA,PPFIA2,GTF2E2,GFPT1,CYB5R1,TXNRD1,GSTT1,RFC2,MRPS17,SRSF4,TRIM26,PPAN,MORC2,AKT2,CASC3,PEA15,NCKIPSD,NAPA,PIP4K2C,PYCR2,CDC16,RPL22,DNPH1,SNX3,YES1,ARMC6,CFAP298,UBE2I,RPS20,SNX12,GANAB,CAB39,GLTP,EIF4A3,QNG1,STUB1,PDCL,EPHX1,TM9SF1,CDAN1,OXSR1,MRPS34,COMMD3,EEF1E1,PFKFB2,HMGB1,SMC4,H2BC12,ARPC2,PRPF4,MGAT4B,EXOC2,PSMD7,GLO1,MFN1,MPG,GTF2E1,TLE1,SLC25A17,ATP5PD,POLE3,EIF2B2,LRRC4B,SRP14,MRPL49,PPP4C,BCS1L,UBR7,EEF1A1,LBR,IRGQ,PRDX4,MSH6,RPS13,TOM1,THRAP3,CAMK2G,PAK1IP1,PC,DLG1,POLR1B,PRSS1,SLC38A1,FTSJ3,COMMD9,LAMTOR1,MLF2,PCCB,PPP5C,SNRNP40,CYP27A1,ATP5F1B,CAVIN2,GTF2F1,PIP4P2,PIH1D1,FDFT1,GAMT,CD59,ZNF428,CNPY3,GOSR2,PAFAH1B1,LDAH,SELENOO,MRPS7,OXCT1,EMC1,PRCP,SNRPA,HSPB1,STAMBPL1,CNTFR,UTP6,NT5C2,CIAO3,PGS1,DYNC1I2,TRAPPC10,MPDU1,HOMER3,CRKL,RPL18,RAB4A,RANBP1,TOP2B,CCT8,ANAPC4,DNAJC10,RPS17,MORF4L1,VPS39,SUCLG2,PPAT,ATL1,GCFC2,ACOX1,RPS3,GSTP1,EIF2B3,SPRYD4,TCP11L1,RPRD1B,MRPL10,SETD3,PPP1R8,CAPN1,MARS1,CRYL1,NAPG,HNRNPH2,LANCL2,SMAD4,KLHL22,TMPO,FCHO2,DNAJC1,TRAPPC3,NUDT9,COMT,ARMC1,CAMLG,STT3A,EEF1B2,TBC1D4,TSPAN3,TFRC,ZMYM3,WBP11,MTCH2,MRPL47,RAP1A,H2BC14,FKBP8,CHDH,DYNC1I1,ERO1A,STX18,PALM2AKAP2,SMARCE1,PRPF31,ACO2,NIBAN2,USP5,PRRC2A,CLIC4,ERH,B4GAT1,MAT2B,LAMTOR3,TRIM46,MED17,FAM177A1,ELOVL1,LARP4B,CRYAB,USP39,TOR1AIP2,CA12,ACTL6A,PYGB,CSRP1,STX7,CMTM6,ATP6V1G2,PAFAH1B2,CFDP1,TMEM30A,PPM1B,BABAM1,VPS26A,ATG9A,WDR44,PRKCQ,SLMAP,IFIT2,RPL8,ITGB5,NDUFS6,OTUD6B,NEU1,BUD23,CSNK1E,FLOT1,SACM1L,GTF3C3,ASF1A,S100A10,ACADS,PRPSAP1,HSPD1,HERC4,MAPRE1,LRP6,SH3BP5L,SDF2L1,HMOX2,DNAJC8,FBXO7,RPL26,DHPS,HSPA14,SH3BGRL,COPE,GNPDA1,MSN,RPS12,DNASE1L1,METAP2,TUBA1B,GXYLT1,HNRNPH3,RPL26L1,CZIB,GOLGA5,METTL14,DCTN4,CCNA2,DDAH1,ARHGAP1,PCK2,RABL3,TMUB1,BRIX1,NF2,RTN4,TCEA1,OSBPL8,ECD,EIF5A2,TMBIM6,ATP1B1,HM13,MOV10,H2AC14,MRPL24,RPL35A,RB1,ACTA2,RPL12,SMAD3,PEX5L,DTD1,DHRS7B,VAC14,NDUFS3,GPX7,GINS4,UBE2V1,PGM1,FNTB,APOBEC3D,TCAF2,ADD2,VTA1,FASTKD5,VRK1,DNAAF10,NOC4L,LIPA,CASTOR2,CPNE2,RPL23A,RAB1A,PPP1R12A,MRPS25,S100A11,PSMD14,CKB,ADK,STX16,SLC1A3,CUTA,TAX1BP1,MATR3,TAMM41,STAT1,RETREG3,PRMT5,SMU1,GGT7,TOM1L2,ZC3H14,LAP3,CERS6,ITGAV,GOSR1,NDUFS2,TRA2B,TMEM106B,SPECC1L,MAGOH,ARMC8,CDC23,DRG2,BPNT2,GSTO1,CTNNB1,BTF3L4,RAB5C,PTDSS1,IFI16,TRMT61A,OSBP,SNRPA1,DBR1,FAHD1,ANXA4,SWAP70,HDHD5,SIN3A,RAB31,SLC4A8,PTRH2,PLS3,RPS7,NUP37,NCSTN,ABHD6,TFG,KGD4,RUVBL1,ALKBH4,UBE2H,ALKBH5,OAT,BICD2,NIF3L1,CISD1,ATP1B3,PHKA1,RPL7A,RAB2A,HPF1,STAT5A,PITPNB,SEC61A1,SEPHS2,CDC42,UGP2,GRPEL1,OGDHL,STK38,SMG5,DERL1,PGK1,TRIM3,PML,NBN,RPL27,MAIP1,ATP6V1D,AKAP8L,SMG8,CD81,DHRS7,LMAN1,SLC38A2,MIF,MTAP,NT5DC1,DSTN,ADD1,UBE2N,GNAI3,CAPN2,GNPNAT1,MVD,ATP5PB,MPST,SEPHS1,MEPCE,BCAP29,ZNF451,MAP1B,PFDN6,MYO6,MCM3,RRN3,CFAP20,USP13,KDSR,RBBP4,RPL7L1,MTM1,AP2M1,RPL37A,RMDN3,PARP2,CPSF1,APOBEC3G,FAU,FAM3C,MYL6,NDUFA5,ETF1,EHD1,FABP7,FTL,PSMC1,NSFL1C,NPTN,NUBP2,CCDC86,NQO1,AHSA1,RASSF8,RSBN1L,KDM2A,RHOG,ATG7,MRPS35,STOML2,PRDX1,RAB11B,NPC2,OS9,LRWD1,NTMT1,SNX1,SPTAN1,ATXN10,NOP58,COPS7B,KIF3B,RPLP1,THY1,GATD3,TSG101,XPO5,OTULIN,ENPP4,CCS,MARCKSL1,FEN1,EIF2D,ANP32B,PPWD1,AP1M1,RRAGB,LASP1,RPS24,JAK1,SLC39A7,TMT1A,REEP6,GMPS,USP14,NONO,CYRIA,SEC13,CTSD,NDUFB10,DDAH2,RPL13A,MAGOHB,PELP1,IFRD1,NOL7,HSP90B1,TIMM23,P3H1,TOX4,CRAT,MYL12B,FUT8,SAP30BP,TMEM209,USP8,PPP1R2,CERS2,IL1RAP,GPX4,SQSTM1,SLC2A3,CSTB,PNO1,NCDN,DNAJC7,ESYT1,SLC2A1,RAB23,RELL1,CAV1,DBT,ARF6,RAD23B,SRP72,NUDT16,ILF2,KRIT1,PPIF,MAP1LC3B,MDC1,EIF3E,SNRPG,MRPL22,TMX3,RGS6,HINT1,TAGLN3,SEPTIN7,GLUL,H2AC25,SLC25A10,ELAVL4,RBM27,GCC1,RPL39,TBCE,FBXO22,PSMD6,USP16,DYNLRB2,TACO1,SIGMAR1,PAK2,SSR3,PITHD1,UBE2D3,HNRNPA0,P4HA2,ANKRD50,YWHAB,SMAD9,FKBP4,IKBKB,STK4,TBC1D5,CST3,SYNJ2BP,LANCL1,FAM98A,CORO1C,S100A8,ADGRG1,CSTF2T,CCDC134,HNRNPDL,RPL28,HMGN4,PDIA6,RUVBL2,RPAP3,PABPC1,RINT1,TMEM87A,PSMG3,SNTA1,CRLF3,EIF3G,NCAPG2,SLC6A6,TIA1,PTPN11,RPF2,NAA50,DUSP3,ROCK1,GMDS,RPL10L,SGTA,PAFAH1B3,PSMA6,TRIM36,GIT2,UTP15,SAMM50,IDH2,ZNF326,VIPAS39,SDCBP,GALNT1,NTPCR,PLP2,SPTBN1,UBE2K,KDM1A,PRDX6,ARHGEF6,THUMPD1,BANF1,RPL10A,AGPAT1,BECN1,PSMG2,CDC5L,ILVBL,CNPY4,AKR1B1,MCL1,NDUFB4,COX4I1,AIP,SDHB,SYNCRIP,PSMC3,IK,DNAJC2,NHERF1,ARPC3,TP53I3,RBM34,ACTR1A,ARHGAP12,CDK4,PREB,SLC6A8,TOLLIP,THG1L,RPL3,SLC16A1,ABCE1,ATP2B4,NOSIP,ILK,HTRA2,ARMT1,SCFD1,RPS5,PFDN4,CCDC25,YWHAZ,CAPG,RAB11A,TUBB,LGALS3,EIF4A2,RANBP6,SNRPD1,GLIPR2,ARCN1,VPS18,H2AC1,VAPB,KCTD12,STXBP1,ATAT1,RRAGA,YTHDF1,SRI,CYFIP2,TBC1D24,HNRNPD,MRPS26,VCPIP1,CDK5RAP3,WDR12,NDC80,HMGA1,PDIA3,NUF2,STK3,NUP35,ATP6V1A,PSMB4,SART3,UCKL1,STX12,POLR2C,NME1,PRKAG1,RPN1,ACTN4,RPL29,ANP32A,ARFGAP1,RBM12,SAR1B,AHCYL1,PSMD12,RPS27A,TAPBPL,GUK1,BAG2,SCD5,PLCB1,GPAA1,NUDT5,AP2A1,NRP1,UQCRQ,CPT2,TMOD3,ENO1,CTNNA1,AGAP1,WTAP,DCTD,MET,STAMBP,ABHD5,FTH1,SEC22B,PDHB,PPIH,IDH3A,INPPL1,SOD1,PRIM2,HELLS,DVL2,NME2,POR,SPATS2L,MSMO1,MRPS23,MDM2,CDK9,CHID1,DCK,KRR1,EIF4E2,CAMK1,SEC14L1,EXOSC8,CD2BP2,MAP2K3,PTGES3,CNOT7,PQBP1,FAF1,RCL1,ZMPSTE24,H2AZ2,RPS6KA4,BAG3,DRAP1,PSMD1,HNRNPC,APEX1,NCKAP1,POLR2B,MRPL13,DLST,CNDP2,EIF4B,MMP14,LAMP5,SEC62,PSMB3,TOMM22,MTMR6,LYPLA2,SERPINB6,SF3B1,RPS28,AVL9,DDT,ARHGAP5,YWHAH,XPO1,PFDN5,INPP4A,LAMP2,DDX50,AASDHPPT,CDK17,STX5,GYS1,FUBP3,RPS23,PDHA1,EEF2,NUDCD3,TUBA1A,GCLC,TRMT1L,CCAR1,HNRNPF,PSMA1,TRIM21,GNA11,PDCD4,ENDOD1,GLOD4,CFL2,PSMB2,CARS1,NUDT4,UBA3,TXNDC12,CTSB,ELMO1,MACROH2A1,NECTIN2,SF3B6,CDIPT,LEMD3,LUC7L3,CYC1,TFB1M,TFIP11,CLU,WDR3,TEX264,DDX46,LIN7C,TSNAX,TRMT5,KPNA1,TPM3,ELOC,PCYT1B,COX5A,MYL12A,STX6,CAND1,RAC2,G6PC3,SSBP1,ACSL4,ITGA6,CCM2,DDX42,SURF4,RPSA,CTSC,RDH11,PSMA5,ATP1A2,DHX9,CLPB,GLCE,SP1,LMNB1,ATP1A3,ELMO2,BLVRA,MCM4,RBM15B,GGH,PDE4B,RNF40,FMC1,SNRPB2,TNPO3,CHCHD3,DYNLL1,TSN,UMPS,MB21D2,SERINC1,PIGK,UBE2S,ATP5PO,MED23,RAB6A,PPP1CB,IDH3B,WDR77,NT5C3A,GPC1,LZTFL1,NUP50,GNA14,TTC1,DCTN3,THOC3,CXCR4,RPL23,LRRC57,TST,EIF3D,PRPF19,TAF7,CETN2,ERLIN1,SNX2,CYB5A,COPS2,PBDC1,NEO1,MYEF2,GTPBP1,RBPJ,VPS33A,VAMP2,MMAA,YIPF3,NUP153,HS2ST1,MCM6,RBBP7,VPS26B,ZC3H7A,TRIP4,PNPO,EPHA2,IVNS1ABP,CHORDC1,PPP1CC,KPNA6,CAP2,SMAD5,SH3BP4,VKORC1L1,DYNLT3,SLC25A4,ZNF622,LDHA,RAB14,UBASH3B,DTYMK,SCAMP2,OPTN,RPLP0,LSM2,LMNA,JUP,CNP,ELP3,SIPA1L1,RBFOX2,PSMC4,RPS14,POLDIP2,RPL4,GTF2I,NPM3,SYVN1,RETREG2,CD9,MPHOSPH10,NOVA1,LRRC40,GMPPA,CALR,FAM118B,PRNP,RGS10,CD151,PPP1R18,ALCAM,PWP2,EHBP1,SRPRA,HACD3,APEH,RPL15,PGM2L1,DDX39A,ALG11,CHKB,MRPL11,TBK1,ARF4,BACH1,WASL,TF,CTNNBL1,KATNAL1,NSDHL,THOC6,MCAT,OSGEP,ICAM1,H1-10,EPS8,COPS7A,SF3B4,ST8SIA5,TBC1D13,PLAA,ADSS2,CTBP1,PALS2,NEK7,SHMT1,SAP18,RER1,RAB5A,PYM1,DRG1,DCAF5,IQSEC1,MRPL9,PPIB,PPFIBP1,MACROD1,TOR1B,TMEM97,VAMP7,TRIR,PAIP1,HEBP1,DIPK2A,MAGED2,SRSF1,FABP5,AAMP,ZRANB2,UCK2,NUDT19,PIR,HPCAL1,TRAF2,ISG15,SUPT5H,ARFGEF1,MAGEC2,SATB1,KRAS,RTCB,ACTR1B,RABGGTB,CALU,ELAVL2,CHPF,EXOC5,CEP85,SRPK2,BCCIP,MYG1,SMURF1,GABPA,CEP41,BUB3,CYBC1,MOB4,MRPS28,ABHD14B,PSMC5,LIG3,ACACA,HECTD1,HEXIM1,CSNK1A1L,RPA2,QRSL1,H2BC11,TRAM1,EIF4E,RBM22,EXOSC4,CWF19L1,TMX2,UGDH,USP15,CDK12,RPS2,COPS5,PGAM1,RBM17,KARS1,DKC1,RBM42,IAH1,RPS16,ARL6IP5,MIOS,SESN2,GFM2,ACOT13,TMEM165,CRABP2,TFCP2,TMEM205,MECR,RRM1,NAA35,CAPZA1,TMEM33,SRPRB,CDC40,REXO2,TRAFD1,MRPS18B,RAB13,SLC25A11,DDR1,VMP1,HSP90AA1,PFDN2,BAX,TMED4,UBTD1,TAB1,ACTB,PRDX2,LRRC8A,GPR89A,SNRPD2,ENO2,FAM91A1,HEXB,MFAP1,ARMCX3,ISOC1,PSMB7,CEND1,NDE1,FBXO30,ATP6V1G1,RP2,PPP2R3A,PSMA3,EXD2,ATPAF2,DICER1,PDAP1,VPS4A,MED4,DCAF11,ACTL6B,ZNF207,PPP2R5A,DHX15,SRSF10,PPIA,SNX18,RPLP2,TYMS,PSMB5,DOHH,SNRPE,MTMR2,GDI2,PCDH17,CTNNA2,ERLIN2,PPP2R1A,LYPLA1,RAF1,NAA15,COPS4,RAD21,TMED7,BPGM,ZNF592,DHX16,MKLN1,HECTD3,PCNA,BCKDK,HNRNPA2B1,SYPL1,SMAD2,CDC73,ARFGAP3,RACGAP1,ZNF687,CIAO1,STK38L,FAH,CEP97,FERMT2,PNP,ALB,ODR4,CMBL,RARS1,MEST,CARHSP1,PICALM,GABARAPL2,CDK7,SLC35E1,UQCRC1,SF3A1,PIK3R2,SLC7A1,SPCS2,RDH10,CLP1,SMG9,CNN3,PROM1,GRSF1,ERCC3,THOC1,SCG2,COG1,LDLR,DECR2,PTPN1,AP1S2,ACTR2,SOX9,GBE1,TOR3A,H2AJ,CMPK1,VPS16,ABHD10,RIGI,FARSA,TMED1,NKRF,TCOF1,SFXN1,HHIP,MDH1,RPS26,CRMP1,FIS1,TBC1D1,SNRPB,BTF3,SFN,HNRNPAB,PSMA4,ACAP2,ALG5,PSMB6,NDFIP1,PTPRZ1,TAGLN2,RRAS2,ZER1,AKR1A1,MAP2K1,PPT1,ACSS2,PTAR1,USP6NL,GINS3,PHB2,SRSF2,FXR2,DDX5,MIA2,DDX39B,PEBP1,CBL,DDX1,H2BC17,DEGS1,AK2,SLC8A1,DDRGK1,NDUFV2,YWHAG,IFT25,CHMP2A,HSP90AB1,CCT7,SUMO2,SNRPD3,HNRNPL,RAB1B,WDR82,CD63,PSME2,H2BC1,HEXA,RAB18,RPS4X,XPNPEP1,ROCK2,PSMA2,CDK5,LSM14A,ABCF1,SORD,MRPS16,DNAJC5,GORASP2,ST13,CFL1,CCNB1,TRIM32,NDUFAF2,CLCN6,CDC20,EIF4H,SRP54,PSPC1,UQCRC2,SSR1,CD2AP,PIP4P1,WDR55,HDAC3,NME4,RPS15,SNX33,DLAT,GFM1,LSM12,MAPKAPK3,IRF3,SEPTIN6,RBM23,SMCHD1,EDC3,RPS27L,CPNE1,CDK6,RAP1B,ALYREF,METAP1,DISC1,PIK3CA,CBX3,TMSB10,RPL17,TGFBR2,HNRNPK,RPIA,LRRN4CL,PSME1,MYD88,CBR3,NOA1,GALE,SAMHD1,AK3,RFC5,CUL3,TXNRD2,VEZT,RPL19,SARM1,CYB5R3,EIF3K,ARF1,VAV2,TIMM29,FAM234A,UNC45A,G3BP2,FOXP2,ZDHHC17,POLA2,ATAD1,PTN,TRUB1,WBP2,CAMSAP2,PDCD10,CDH13,PSMD10,MMUT,UBXN6,HMBS,PSMD3,CCAR2,RPL7,OCRL,HP1BP3,PHB1,OCIAD2,DNM2,CYB5B,PLD3,EIF1AX,PGGT1B,EZH2,STIM1,MAK16,TMT1B,ACO1,TPBG,RFC3,SIAE,RETREG1,UNC119B,ETFA,GNL1,MYORG,LAMB2,G3BP1,UBE3A,ERP29,CDKN2C,XPOT,TDP1,STK24,CCDC22,TUFM,ATP5F1A,RETSAT,CSK,SEC63,TECR,CD47,TXN,TRIM24,ACAT1,PRKRA,GSK3A,RTRAF,SMAP2,TMSB4X,CYRIB,PITPNA,TTI2,H2AC7,TMX4,GHITM,CDK1,EIF3J,EDF1,SPR,TPT1,SNRPN,ATG16L1,AATF,CRYZ,NUCKS1,EIF5B,MTDH,MAVS,ITGA2,FADS2,MME,TTL,HDAC6,ISYNA1,GMPPB,RNF14,NFKB1,SLC25A12,NOP9,G6PD,MAPRE2,TOP1,EIF2B5,SEC23A,HSD17B11,UBP1,DFFA,AIFM1,H2AZ1,CASK,PPME1,HSPA13,UAP1,GGCT,AGPAT5,PSMB9,SLC29A1,YTHDF2,CCDC47,GALNT2,CTNND1,OLA1,RNF20,HSPE1,HSD17B10,EMC2,RING1,EHD4,THTPA,CHTOP,SPCS3,HMGCS1,MBLAC2,PAPOLA,ATP6AP2,PSMD4,KBTBD2,ANAPC2,PHKB,GTF2F2,EFHD2,NCOA5,KLC2,OGFOD3,UBAC2,MRPS18A,DHRS4,RPL27A,GNB4,STAU1,AKAP1,HSPA8,XRCC5,RFC4,FAM20B,GSTM3,PNPLA8,UQCRH,TCP1,LYAR,AFTPH,EIF2S1,GSTCD,FAAP100,EED,TNIK,RXRG,PTK7,MTA2,PNMA2,STMN2,KIF2A,TNPO2,NAA16,POLDIP3,VDAC1,SEC11A,EFNB1,SNX5,ATP1A1,H2BC9,GSTK1,SUB1,MAT2A,TNFAIP3,NMI,CSTF3,PPP1R10,ADRM1,DHRS13,RALA,PYGM,GPX1,EIF2S2,UBE2M,PRKCA,VPS4B,GALNT4,SMYD3,GTF3C4,AKR7A2,HSPA5,ZC3H15,RAB9A,POLD2,APMAP,SNRNP70,NOS1AP,TUBG1,TMA16,CSNK2A1,RBFOX3,ACOT8,CMSS1,SLAIN2,SURF6,LRRC14,SELENOI,LCMT1,PREP,ACADSB,GPD2,CHAMP1,HADH,H2AX,IPO8,MNAT1,KPNA2,L1CAM,RBCK1,IDH1,RUSF1,PCYOX1L,NAE1,LSM14B,PAXX,ELMOD2,SLC41A3,MRPL16,PMPCA,PYCR1,TM9SF4,UBE2V2,ABHD12,MRPL23,RPS9,POLR3B,S100A6,TRMT6,FKBP1A,SLC25A3,ANXA7,IRF2BPL,FKBP10,PGRMC1,CMAS,CDSN,SRM,UCHL3,EMG1,TRIM5,TXNL1,PRKD3,DNAJC3,HSDL1,ATP2C1,COTL1,RB1CC1,MRPL18,SKIC8,HNRNPA1,MAP1S,AGK,SDHAF2,SNX17,MRTO4,RPL9,RPS11,BZW2,RIMOC1,PPID,FAF2,DPH5,DCAKD,HSDL2,SSRP1,ATP5F1D,MRPS11,SRSF7,HINT2,THNSL1,MAEA,ZYX,SCYL2,PREPL,SLC25A5,GGCX,PPIG,ASCC1,CNTNAP1,RALB,VIRMA,GNAI2,PDCD5,DEK,UBE2L3,EIF2AK2,CTTN,MRPL53,SHOC2,SH3GLB2,STOM,SLC12A2,NUDT12,UBLCP1,UBA52,CXXC1,DAD1,YKT6,MRPL17,GID8,PPM1G,TRAPPC4,PPIC,DAG1,ATP5MG,TOMM70,HTRA1,DCUN1D1,PSMB1,DLGAP4,SOD2,ITGB8,GNPDA2,CCT5,H2AC6,PSEN1,TTC4,FN3KRP,ERLEC1,HUWE1,SERPINH1,ATG3,CCT2,CIRBP,UFD1,CPSF2,LDHB,APOBEC3B,RPL10,CBX5,STAT2,TRMT11,CMTR1,VDAC2,TRMT112,CSNK1A1,NUFIP2,ACAA2,GSTM2,EDEM3,QTRT2,ATP6V1C1,EEF1G,UFL1,GPHN,TAPBP,NUDT2,CRTAP,TENM3,EXOC1,RPL6,SEC61A2,BAZ1B,PAPOLB,CHI3L1,PEG10,NOB1,RPS10,RBM5,RPRD1A,RAB35,GNAQ,HGS,TUBB4B,RBBP9,ETFB,DHX38,PRPS1,RAB8B,UTP25,FKBP2,DCTPP1,MYO1B,EWSR1,RPL31,CDKN2AIP,SNX14,MECP2,MTPN,PRKACB,NUDT1,AKT1,SLC25A1,IFI35,SMARCA5,RGL2,DYRK1A,ACP2,IDE,PPP2R5E,PHAX,CSNK2B,ALG2,CSNK1G3,PAAF1,AGO1,ARFIP1,NLE1,TXNDC17,BAP1,MAP4,H2AC4,SHC1,RPL24,API5,GAPDH,LYPLAL1,PPIL4,ANKMY2,MTMR12,RAB39B,ESD,TMED9,GNPAT,XXYLT1,MGME1,RPL32,MRPS9,SH3GLB1,CAPZA2,EXOC3,TP53,FAM162A,STRBP,LPCAT3,PHF1,CSE1L,RAB3B,H3C1,PDE12,AKAP12,NEDD8,NUP107,PIK3AP1 |
| 5.182e-58 | -131.90 | UBE2H (ubiquitin conjugating enzyme E2 H) | protein interactions | 7328 | 1950 | 861 | 19454 | 5460 |
CSK,CTSD,SEC13,ATP5F1A,NONO,TUFM,GMPS,XPOT,PELP1,INPP5K,RTRAF,TXN,RPL13A,TECR,HOMER1,WDR83,TPT1,CDK1,HSP90B1,PNO1,CSTB,MTDH,GPX4,EIF5B,IL1RAP,NUCKS1,ISYNA1,HDAC6,SLC2A1,TCEAL9,ESYT1,DNAJC7,H2AZ1,SSU72,AIFM1,SEC23A,POLR2I,TOP1,G6PD,CAV1,CCDC47,YTHDF2,GGCT,ILF2,SRP72,CASK,SLC25A10,SEPTIN7,HINT1,EMC2,HSD17B10,POLL,HSPE1,RNF20,MRPL22,CTNND1,OLA1,SNRPG,EIF3E,ALDH1L1,CFAP20,RFC5,SAMHD1,AK3,MCM3,MYO6,BOLA1,FAU,ARF1,CPSF1,EIF3K,CYB5R3,RPL37A,AP2M1,SLC30A7,SYBU,RPL7L1,RBBP4,SPINDOC,MAD2L1,RPL19,NRDE2,VAV2,MYL6,NDUFA5,ATP5MK,RMND5B,NUBP2,PSMC1,UNC45A,PSMD3,PRDX1,MRPS35,FRA10AC1,STOML2,DPY30,PSMD10,AHSA1,NQO1,DNM2,PHB1,XPO5,GATD3,RPLP1,HP1BP3,NOP58,CCAR2,SPTAN1,RPL7,MARCKSL1,SF3B5,RNF126,AP2S1,PLD3,NDUFA4,JAK1,SLC39A7,RPS24,G3BP1,ANP32B,PCGF6,RFC3,RPF2,MAT2A,SUB1,PTPN11,EIF3G,ATP1A1,SERPINB1,RRP7A,PSMA6,EIF2S2,CBLN1,RALA,GMDS,ROCK1,PPP1R10,SPTBN1,SUMO1,NTPCR,ZNF326,SAMM50,UBE2M,PARD6A,TRIM36,BANF1,LGI1,PRDX6,KDM1A,MRPL41,ZC3H15,TOMM20,HSPA5,ACOT8,CSNK2A1,TMA16,TUBG1,SNRNP70,RPL10A,AIP,SDHB,SYNCRIP,COX4I1,SURF6,CDC5L,SLAIN2,CDK4,IPO8,HADH,ACTR1A,RBM34,DNAJC2,ARPC3,IK,SELENOF,PSMC3,TAF2,NAE1,NOSIP,ABCE1,SLC16A1,RPL3,RBM41,IDH1,KPNA2,PAPOLA,CHTOP,RBM27,TACO1,GTF2F2,PSMD4,PSMD6,FBXO22,RPL27A,KLHL3,YIPF5,RFC4,SLU7,XRCC5,MRPL34,HSPA8,HNRNPA0,PITHD1,STAU1,RANBP10,GSTM3,STK4,FKBP4,YWHAB,SERPINC1,CORO1C,EIF2S1,LYAR,TCP1,PNPLA8,LANCL1,PPIL3,KIF2A,MTA2,PABPC1,RUVBL2,SEC11A,PDIA6,RPL28,HNRNPDL,POLDIP3,BRAP,ASCC1,YPEL5,AP2A1,PPIG,DNAJC19,MRPL53,CTTN,ENO1,EIF2AK2,SPIN3,TMOD3,UQCRQ,UBE2L3,DEK,PDCD5,VIRMA,PIP5K1A,UBLCP1,COX6C,ZCCHC17,KRT7,PPM1G,SOD1,GID8,MRPL17,PDHB,MRPL20,PMM2,ATP5MG,FAM133B,NME2,BRD3,WDCP,EIF4E2,PSMB1,HTRA1,MRPL50,CDK9,MDM2,MRPS23,CCT5,MAP2K3,CD2BP2,EXOSC8,CAMK1,RNF133,HUWE1,FN3KRP,PTGES3,H2AC6,SMN1,RAB11A,F2,RPS29,YWHAZ,RPS5,HTRA2,TRMT6,RSRC1,POLR3B,SNRPD1,RPS9,LGALS3,TUBB,ABHD12,PGRMC1,ARCN1,SLC25A3,TRIM5,TXNL1,JADE1,CYFIP2,YTHDF1,SRM,CDSN,CMAS,PDIA3,MAP1S,HNRNPA1,MRPL18,SKIC8,DROSHA,MRPS26,RB1CC1,HAX1,HNRNPD,RPL9,PSMB4,MRTO4,ATP6V1A,AGK,ACTN4,RPL29,FAF2,RPN1,PRKAG1,NME1,EXOSC3,RPS11,JPT2,SART3,SLC25A5,NEK9,SCYL2,NUDT5,ZYX,MAEA,MRPS11,SRSF7,BAG2,SKA1,RPS27A,PSMD12,SAR1B,AHCYL1,SSRP1,PSMB2,SLC25A1,MTPN,CEP70,GLOD4,IGF2BP1,CDIPT,SF3B6,CSNK2B,MACROH2A1,TXNDC12,IDE,UBA3,NOPCHAP1,HBB,RNF146,TFIP11,CYC1,LUC7L3,RAG1,DDX46,LIN7C,GID4,TXNDC17,WDR3,PPIL4,ELOC,GAPDH,TPM3,RPL24,KPNA1,MAP4,MRPS9,SSBP1,RPL32,PLG,CAND1,MYL12A,STRBP,RPSA,TP53,CAPZA2,MRPL33,DHX9,PSMA5,MRPS33,CSE1L,HNRNPC,LDHB,PSMD1,CCT2,SERPINH1,RCL1,VDAC2,CMTR1,DLST,MRPL13,HDDC2,POLR2B,APEX1,NCKAP1,RPL10,EFHD1,NUFIP2,EIF4B,TRMT112,CSNK1A1,RPS28,GPHN,SF3B1,MED13L,UFL1,SERPINB6,EEF1G,LYPLA2,SLC37A4,DDX50,LAMP2,RPL6,XPO1,YWHAH,QPCTL,CCDC71,FUBP3,SELENOM,RPS10,NOB1,AASDHPPT,GLRX,PEG10,RBBP9,EEF2,TUBB4B,DCUN1D5,RPS23,RPL31,EWSR1,TRIM21,MYO1B,PSMA1,HNRNPF,DCTPP1,CCAR1,UTP25,PRPS1,AAMDC,ZMYND19,CAP2,PPP1CC,CHORDC1,DCAF16,PIP4K2C,IVNS1ABP,PNPO,STUB1,EIF4A3,GANAB,UBASH3B,RPS20,UBE2I,LDHA,SLC25A4,RPL22,PSMC4,RPS14,EEF1E1,ELP3,CNP,JUP,MRPS34,LEPR,RPLP0,PRPF4,ARPC2,NPM3,GTF2I,SMC4,HMGB1,RPL4,NHP2,POLDIP2,CALR,LRRC40,GLO1,PSMD7,HACD3,SRP14,PWP2,SLC25A17,MRPL11,EEF1A1,DDX39A,LBR,RPL15,MRPL49,PAK1IP1,TF,THRAP3,RPS13,MSH6,PRDX4,FMC1,MCM4,BLVRA,ELMO2,LMNB1,RIT1,RAN,UBE2S,PELO,TSN,DYNLL1,UMPS,RPL35,CHCHD3,SNRPB2,GNB1,LNX2,WDR77,PRDX3,PPP1CB,IDH3B,ATP5PO,RTF2,THOC3,ATP5IF1,RNF10,HADHA,PMAIP1,MCMBP,SKP1,PRPF19,CLPX,WDR11,EIF3D,DDX23,HBA1,RNF139,RPL23,WDR6,THOC2,PBDC1,CACYBP,NDUFS8,GFPT1,GNB1L,GTPBP1,AKT2,ARGLU1,PPAN,RBBP7,TRIM37,KCTD17,MRPS17,SRSF4,MCM6,RFC2,RPS17,DNAJC10,TRIM23,CALU,RPS3,PSMC5,MRPS28,BUB3,PPAT,SRPK2,CAPN1,SNRNP27,MRPL10,ACACA,CWF19L1,EXOSC4,LCP1,RBM22,EIF4E,MARS1,KARS1,RBM17,HP,LANCL2,RPS2,CDK12,USP15,GTF2B,EEF1B2,STT3A,COQ8A,RNF128,RPS16,FMOD,NKAP,TMPO,IAH1,RBM42,DKC1,RRM1,SNAP29,RAP1A,MRPL47,EGR2,TBC1D4,SLC25A11,ERO1A,MRPS18B,TRAFD1,SRPRB,TMEM33,CAPZA1,FKBP8,H2BC14,COX16,H1-10,FTSJ3,PLCL1,OSGEP,PRSS1,THOC6,FAM83B,SF3B4,GTF2F1,ATP5F1B,SNRNP40,PPP5C,CTBP1,ADSS2,SNRPA,PYM1,FLYWCH2,SAP18,MRPS7,MRPL9,PPIB,NT5C2,DRG1,HSPB1,FABP5,SRSF1,MAGED2,DYNC1I2,TRIR,TMEM97,UBL5,RANBP1,SUPT5H,NUDT19,KDELR1,SMNDC1,UCK2,ZRANB2,RPL18,AAMP,CRKL,CCT8,SREK1IP1,RTCB,KRAS,STK38L,HSPA14,CIAO1,RPL26,NEURL2,CDC73,MAPRE1,TRIM27,CMBL,RPS12,SFXN2,ODR4,ALB,COPE,PNP,SF3A1,RNF103,CARHSP1,RPL26L1,HNRNPH3,RARS1,RPA3,BRIX1,MOV10,GRSF1,HM13,CNN3,RPL12,ACTA2,TES,RPL35A,MRPL24,CMPK1,NDUFS3,DHRS7B,SFXN1,NKRF,TCOF1,RPL23A,NOC4L,FARSA,ACO2,PRPF31,BAX,PFDN2,HSP90AA1,SNRPD2,ZMAT2,PRDX2,TAB1,ACTB,MAT2B,NDUFAF4,ERH,PRRC2A,USP5,MAPKAPK5,ACTL6A,SUPT4H1,USP39,PSMB7,LARP4B,MFAP1,NKAPD1,PSMA3,MRPL57,PYGB,CSRP1,ZNF207,PPM1B,VPS4A,DICER1,RPL8,PSMB5,RPLP2,KRT8,SRSF10,PPIA,DHX15,CSNK1E,NAA15,BUD23,PPP2R1A,ERLIN2,GDI2,NDUFS6,SNRPE,HSPD1,HNRNPA2B1,PCNA,MKLN1,PRPSAP1,UFM1,DHX16,S100A10,GTF3C3,NDUFAF2,RPL7A,CFL1,ARHGAP21,CHCHD4,OAT,EXOSC1,AP3S2,UBE2H,PSPC1,TMA7,SRP54,SEC61A1,CD2AP,SSR1,RPL27,IRF3,PGK1,RNF34,LSM12,DLAT,NME4,RPS15,STK38,FTSJ1,ENY2,EDC3,SMCHD1,AKAP8L,ALYREF,UBE2N,DSTN,CDK6,MTAP,CPNE1,MARCHF4,RPS27L,MIF,RP9,CBX3,PCMTD2,CAPN2,HBP1,MAP1B,PSME1,HNRNPK,MEPCE,RPL17,PSMA4,HNRNPAB,SFN,BTF3,SNRPB,ADK,CKB,S100A11,PSMD14,MRPS25,RPS26,MDH1,SMU1,PRMT5,TAMM41,MATR3,TAGLN2,PSMB6,ACAP2,LAP3,MRPL12,PEBP1,DDX39B,DDX5,TRA2B,FXR2,SRSF2,NDUFS2,PHB2,PTDSS1,RAB5C,YWHAG,AK2,GSTO1,H2BC17,MGMT,DDX1,ARMC8,MAGOH,HDHD5,WDR82,HNRNPL,DBR1,SNRPA1,SNRPD3,SUMO2,CCT7,HSP90AB1,PTS,H1-3,RPS7,PLS3,ABCF1,LSM14A,CDK5,RUVBL1,RPS4X |
| 7.024e-48 | -108.57 | ribonucleoprotein complex | cellular component | GO:1990904 | 1101 | 542 | 19108 | 5553 |
MIR200A,MAGOH,MIR656,MIR106B,FTSJ3,RPL13A,MIR370,MRPS23,PRPF18,RPL7L1,RPL26,TIA1,MIR218-1,MIR491,MIR657,ARMC7,ZMAT5,ACTB,RPL3,MIR1180,MIR320A,MIR29C,MIR671,MIR106A,MFAP1,TFIP11,MIR144,MIR136,PPP1R8,RPL22,MIR145,AATF,NOC4L,RPL8,MIR32,RPP21,MIR448,HNRNPAB,PWP2,MRPL16,MIR636,DDX1,MRPS9,KRR1,MRPL51,SRSF2,APOBEC3G,MIR146A,MRPL57,MIR711,HEXIM1,MIR1249,MIR939,POP5,MIR137,MIR624,MIR346,MIR609,MEPCE,G3BP2,RPP14,LSM14A,MIR148B,MIR640,MIR936,DICER1,MIR542,MIR628,RPL10L,POP7,HSD17B10,MIR488,NOP9,KHDC4,GRSF1,MIR155HG,PHAX,RBM3,RPS13,MRPL17,LGALS3,SF3B5,RUVBL1,RPL23,RPS3,MIR24-1,AURKAIP1,ELAVL4,GCFC2,DHX15,MIR874,MIR361,CELF6,SNIP1,PABPC1,MIR215,MIR187,RPL7A,RPS27L,MIR497,MIRLET7I,RPL29,MIR214,LUC7L3,MAK16,SRP72,HNRNPA2B1,MIR223,ACTN4,ZNHIT6,WRAP53,UTP15,MIR222,JAKMIP1,MRPS18C,MIR216A,LSM10,XRCC5,MIR101-2,MIR577,ZMAT2,RPL39,MIR17,MIR221,MRPS18A,DDX5,EIF3K,SMU1,SNRPA1,HNRNPA1,MIR331,EIF2D,MIR7-1,MIR551A,RPS4X,UBA52,MIR30B,MIR152,SNRPG,MIR675,MRPL33,DYRK2,AKAP17A,MIR611,TRIM21,MIR132,MRTO4,SUGP1,PABPC1L,MIR96,CSNK1E,MRPS33,MRPS28,SRP14,MRPL34,MIR612,RPF1,MIR578,MIR139,RBM5,MRPS25,RPL35A,DYRK1A,MIR29A,IVNS1ABP,TRA2A,MIR330,MIR484,RPS16,MIR661,MRPL13,DHX16,RPS7,MIR615,MIR150,RPS26,IMP3,MIR887,LSM3,MIR143,MIR33B,MIRLET7G,MIR558,MIR126,SNRNP48,RIOK2,MIR24-2,ESS2,EIF3J,MRPS18B,RBMS2,RPP25,MIR31,RPL19,MRPL22,MIR450B,RPL27,MIR30E,MIR186,EIF3G,RRP7A,ILF2,MRPL11,G3BP1,MIR643,MRPS21,MIR383,USP39,GAPDH,SRFBP1,RBM41,IK,MIR142,MIR552,RPL28,MIR21,MIR147A,MIR30A,CASC3,MRPL36,RBM42,CPEB1,MIR1-1,SF3A1,NOL7,SNRNP40,MIR105-1,MIR147B,MIR551B,MRPL53,MIR345,CD2BP2,SLU7,RNF113A,RPSA,CHCHD1,LSM6,MIR1-2,DDX39B,RPL10A,UTP23,MIR598,DHX38,CIRBP,SYNCRIP,LSM4,SMG5,FAU,MIR920,RBM12,SNRPD1,TOP2B,PPWD1,PPIL3,MIR500A,IGF2BP1,MIR605,TERC,MIR20A,MAGOHB,MIR877,MIR216B,SCNM1,MRPL18,EEF2,MIR105-2,SF3B6,MIR212,ELAVL2,MIR218-2,PNO1,NOB1,CDC5L,EIF3D,MIR107,MRPS7,MIR553,MRPS17,RPL37A,MRPL47,RPL23A,RPLP2,MIR592,RPS17,NHP2,MIR100,DDX42,MIR938,STAU1,MRPL9,WDR12,NSA2,MIR873,RPS5,MIRLET7C,MIR98,PRKRA,DDX23,HNRNPH2,MIR23B,MIR205,RPS20,RPL15,MIR99A,MIRLET7B,EMG1,MIR632,MIR184,MIR505,MIR580,RPS10,UTP6,MIR631,RPL6,MIR556,RPS28,RCL1,RBM22,RPL26L1,SNRPD3,MIR25,ARFGEF1,MRPL24,MIR653,MIR761,MIR503,HNRNPL,UTP25,WDR3,MIR504,MIR604,MIR204,RPL9,HNRNPK,HNRNPC,SF3B1,LSM2,MIR16-2,HSPA8,MRPL41,MIR141,SRSF1,MIR454,MIR148A,MIR30D,XPO1,SNRNP27,FCF1,MIR9-3,MIR593,EIF4E,RPS24,MIR573,MIR942,MIR10B,MIR1227,MRPL12,MIR607,MIR944,SF3B4,MRPL49,RPS15,MIR600,MRPS34,MIR195,ZC3H14,MIR196B,PPAN,ALYREF,MIR130A,RPL27A,MIR9-1,MIR155,MIR338,RPS12,MIR339,PRPF31,MRPS35,MIR9-2,MIR302B,RPLP0,MIR940,LSM14B,MRPL10,HNRNPF,MIR1296,MIR489,MIR198,SNRPA,MRPL50,DHX9,TXNL4A,MIR15A,MIR1251,MIR770,MIR135B,TSSC4,PPIH,EIF2S1,TRA2B,MIR425,MIR377,MIR367,MIR495,MIR191,MRPL20,BUD31,CWF19L1,MIR192,SNRPB2,MIR211,MIR625,MIR197,MIR424,MIR183,MIR572,CBX5,SRP54,MIR342,MIR626,RPP25L,RPL7,XPO5,MIR490,MIR26B,RUVBL2,MRPL23,RPL17,HNRNPH3,MIR129-1,LSM8,MIR502,EIF1B,SNRNP70,MIR190B,MIR133B,MIR200C,RPL12,MIR586,WDR83,SNRPE,MIR764,PRPF19,PCBP4,MRPS26,MIR210,MRPS11,TERT,RPS29,MIR194-1,DDX46,RPS11,CTNNBL1,MIR589,MIR99B,MIR10A,MIR181C,RPLP1,MIR648,AKAP8L,NGDN,MIR581,RPL32,EIF3E,MIR455,DCP2,DKC1,ZCCHC17,MIR194-2,MIR129-2,ZCRB1,EIF4A3,BRCA1,RPL31,MIRLET7D,MIR590,MIR452,MIR190A,MIR149,MIR324,MIR16-1,NOP58,MPHOSPH10,EIF1AX,RPL24,PTGES3,SART3,MIR423,AGO1,RPL4,MIR296,ZNF622,RPS14,MIR140,SNRPD2,PIH1D1,ZNHIT3,MIR569,API5,MIR934,HNRNPD,MIR375,RPS23,RPL10,RPS2,RPL18,MIR618,MIR876,MIR101-1,SNRPB,PABPC5,MIR7-3,CDC40,MIR125A,LSM5,MIR23A,SNRPN,MRPL40,RPS9,MIR185,MIR153-2,RPS27A,RBMX2,MIR153-1,MIR922,RHEB,MIR206,APOBEC3F,MRPS16,TAF9,CWC15,MRPL52,MIR601,RPL35,NUP62,RIGI,MIR7-2,PRPF4,IMP4,MIR335,SECISBP2L,MPV17L2 |
| 2.503e-47 | -107.30 | RPA3 (replication protein A3) | protein interactions | 6119 | 2870 | 1135 | 19454 | 5460 |
PSMD4,PSMD6,EFHD2,GTF2F2,PHF21A,SPCS3,CHTOP,RBM27,NSA2,TMED5,TBCE,PAPOLA,LDB1,HMGCS1,HNRNPA0,EIF1B,STAU1,SSR3,RFC4,SLU7,XRCC5,HSPA8,STK26,AKAP1,PAK2,SIGMAR1,RPL27A,FAM98A,EIF2S1,TCP1,LANCL1,TNIK,SERPINC1,RFX5,S100A8,CORO1C,FKBP4,YWHAB,GSTM3,TBC1D5,VDAC1,RPL28,POLDIP3,HNRNPDL,NDUFB5,RINT1,PABPC1,RUVBL2,RPAP3,PDIA6,SEC61G,MTA2,NAA16,TOP3B,MED9,CCDC134,CSTF2T,KIF2A,RALA,RPL10L,GMDS,PPP1R10,CSTF3,DUSP3,QSER1,EIF2S2,STX10,EIF3G,ATP1A1,SERPINB1,SNX5,RPF2,MAT2A,NAA50,GSTK1,SUB1,PTPN11,FOXA3,KDM1A,TOMM20,HSPA5,APMAP,SNAPC1,THUMPD1,PRDX6,RAB9A,RNF113A,IDH2,SAMM50,PRKCA,UTP15,UBE2M,SPTBN1,CCNH,NTPCR,TRMT13,VPS26C,ILVBL,SELENOI,SURF6,CDC5L,AIP,SYNCRIP,COX4I1,NDUFB4,PREP,LCMT1,AKR1B1,TUBG1,PSMG2,AGPAT1,RPL10A,CMSS1,CSNK2A1,IMP4,KPNA2,MNAT1,NAE1,NOSIP,ABCE1,SLC16A1,RPL3,IDH1,CHAMP1,GPD2,RBM34,ARPC3,IK,TAF2,PREB,CDK4,TNRC6C,IPO8,H2AX,HADH,ACTR1A,ZMYM4,GDE1,RBBP4,RPL7L1,MAD2L1,RPL19,FAU,ARF1,CPSF1,EIF3K,CYB5R3,SLC30A7,RPL37A,AP2M1,SARM1,MYO6,PFDN6,USP13,KDSR,NDUFB6,CFAP20,CUL3,RFC5,SAMHD1,MCM3,NPTN,NSFL1C,ATAD1,PSMC1,POLA2,UNC45A,ATP5MK,FAM3C,MTX2,TIMM29,ETF1,COPS7B,OCRL,NOP58,MPP1,ATXN10,CCAR2,SPTAN1,SNX1,RPL7,NTMT1,LRWD1,RAB11B,DNM2,OCIAD2,PHB1,XPO5,TSG101,HP1BP3,RHOG,LYZ,PDCD10,AHSA1,PSMD3,PRDX1,MRPS35,STOML2,MMUT,G3BP1,LASP1,ETFA,GNL1,PPWD1,AP1M1,ANP32B,RFC3,NDUFA4,TMT1A,UBE3A,RPS24,STIM1,SF3B5,AP2S1,OTULIN,CYB5B,PLD3,FEN1,RPL13A,TECR,SEC63,ZNF507,PELP1,SELENOT,CYRIB,RTRAF,PRKRA,GSK3A,ACAT1,TADA3,CCDC22,XPOT,CSK,CTSD,SEC13,ATP5F1A,NONO,USP14,GMPS,TUFM,EIF5B,NUCKS1,USP8,TMEM209,CRYZ,GABARAP,NCDN,PNO1,MAVS,SQSTM1,MTDH,TOX4,CDK1,TIMM23,GHITM,PITPNA,IFRD1,SAP30BP,FUT8,SPR,TPT1,EDF1,EIF3J,ARF6,MAPRE2,EIF2B5,TOP1,CAV1,G6PD,SLC25A12,AIFM1,SEC23A,SLC2A1,ESYT1,DNAJC7,TOPBP1,GMPPB,ISYNA1,LSM4,POLL,CTNND1,OLA1,GALNT2,EIF3E,MDC1,EHD4,ZC3H11A,SEPTIN7,EMC2,HSD17B10,HINT1,TMX3,UAP1,ILF2,PPME1,RAD23B,SRP72,CASK,CCDC47,YTHDF2,MLLT6,MAP1LC3B,AGPAT5,POLR2B,LRIF1,APEX1,NCKAP1,VDAC2,CMTR1,DLST,TRMT11,CCT2,H2AZ2,ZMPSTE24,SERPINH1,RCL1,MYC,HNRNPC,LDHB,CPSF2,UFL1,SERPINB6,EEF1G,LYPLA2,JAGN1,NANP,SF3B1,NUFIP2,EIF4B,CSNK1A1,CNDP2,MTMR6,ATP6V1C1,TOMM22,PSMB3,SEC62,QTRT2,RPS10,NOB1,AASDHPPT,RAB35,FUBP3,GYS1,STX5,ARHGAP5,CRTAP,DDT,UBFD1,DDX50,CNOT2,BAZ1B,RPL6,XPO1,DNTTIP1,YWHAH,EXOC1,NGDN,PSMA1,DCP2,HNRNPF,CCAR1,DCTPP1,PRPS1,UTP25,GNA11,RPL31,SCPEP1,EWSR1,MYO1B,TUBB4B,PDHA1,DCUN1D5,RPS23,TRMT1L,ETFB,DHX38,GCLC,EEF2,RNASEH1,IDE,UBA3,SF3B6,CDIPT,PHAX,PPP2R5E,MACROH2A1,IGF2BP1,PDCD4,CDKN2AIP,SMARCA5,PSMB2,CARS1,SLC25A1,AKT1,WDR3,DDX46,BAP1,NLE1,ARFIP1,TFIP11,LUC7L3,CYC1,LEMD3,PAAF1,TMED9,KCTD3,CAND1,ESD,SSBP1,ACSL4,MRPS9,RPL32,XXYLT1,GNPAT,H2AC4,RPL24,TAF9,KPNA1,MAP4,TRMT5,TSNAX,DPP4,MTMR12,PPIL4,GAPDH,ELOC,API5,NUP107,PDE12,CSE1L,RDH11,LPCAT3,DHX9,SURF4,DDX42,CAPZA2,SLC25A24,IMP3,STRBP,FAM162A,TP53,RPSA,APOO,EIF4A2,REEP4,TUBB,RSRC1,SNRPD1,POLR3B,RPS9,YWHAZ,BRCA1,CCDC25,RPS5,SCFD1,ARMT1,ILK,CDC123,ZNF250,TM9SF4,JPT1,MRPL16,ELMOD2,CYFIP2,YTHDF1,SRM,CMAS,HSDL1,TBC1D24,TXNL1,RABAC1,EMG1,KCTD12,VAPB,ARCN1,ANXA7,SLC25A3,FKBP1A,RRAGA,PGRMC1,EGLN3,NUF2,RPL9,PSMB4,MRTO4,ATP6V1A,SNX17,BRD9,WDR12,SKIC8,RB1CC1,VCPIP1,HNRNPD,COTL1,PDIA3,MAP1S,HNRNPA1,UBE2A,PSMD12,AHCYL1,SSRP1,NEK9,SLC25A5,ZYX,GPAA1,SCYL2,BAG2,RPN1,PRKAG1,RIMOC1,BZW2,EXOSC3,RPS11,STX12,SART3,JPT2,HSDL2,CA8,DCAKD,RBM12,ARFGAP1,RPL29,ACTN4,JUN,FAF2,TMOD3,MGST3,CPT2,UQCRQ,DEK,PDCD5,VIRMA,GNAI2,CTTN,ENO1,CTNNA1,AP2A1,DNAJC19,BRAP,PDHB,YKT6,DAD1,HELLS,DVL2,SOD1,PRIM2,PPM1G,IDH3A,COX6C,TIMMDC1,SEC22B,UBLCP1,DCUN1D1,TOMM70,CDK9,WDCP,KRR1,EIF4E2,CHID1,COX20,PSMB1,FOXP1,ATP5MG,HUWE1,FN3KRP,SMN1,FAF1,KLHL15,CCT5,CD2BP2,EXOSC8,ATP5F1B,SNRNP40,PPP5C,GTF2F1,LAMTOR1,H1-10,FTSJ3,OSGEP,MCAT,THOC6,POLR1B,COPS7A,PCCB,EMC1,RER1,SELENOO,SNRPA,RAB5A,EP300,PLAA,ADSS2,FDFT1,SHMT1,NEK7,PAIP1,DYNC1I2,TRIR,TOR1B,VAMP7,TMEM97,MACROD1,FABP5,MPDU1,MAGED2,DRG1,HSPB1,PPIB,NT5C2,UTP6,KRAS,SATB1,NUP42,TOP2B,CCT8,RABGGTB,ACTR1B,RTCB,NUDT19,UCK2,RAB4A,ZRANB2,RPL18,CRKL,ARFGEF1,RANBP1,SUPT5H,SOX2,BUB3,GABPA,PPAT,MYG1,SRC,BCCIP,SRPK2,RPS3,ACOX1,GCFC2,LIG3,ZBTB33,PSMC5,RAP2C,DNAJC10,ANAPC4,MORF4L1,EXOC5,RPS17,NAPG,RBM22,MARS1,TMX2,UGDH,CWF19L1,LCP1,RPRD1B,RPA2,CSNK1A1L,EIF2B3,HEXIM1,HECTD1,ACACA,PKIG,CAPN1,SETD3,ARL6IP5,RPS16,TMPO,DKC1,EEF1B2,GTF2B,COQ8A,STT3A,ARMC1,COMT,TRAPPC3,SMAD4,RPS2,CDK12,KARS1,RBM17,PGAM1,COPS5,KDM4B,SRPRB,TMEM33,CAPZA1,FKBP8,SLC25A11,STX18,ERO1A,RAB13,TFRC,TMEM165,TBC1D4,RRM1,NAA35,SNAP29,MTCH2,WBP11,RPAP2,TMEM205,ZMYM3,MB21D2,RPL35,UMPS,TSN,DYNLL1,GNB1,TNPO3,SNRPB2,RAN,UBE2S,PIGK,BLVRA,FAS,ELMO2,LMNB1,RIT1,CUL2,TOMM40,RHEB,MCM4,MCMBP,NT5C3A,COIL,RTKN,TTC1,HADHA,NUP50,MED23,APOBEC3C,ADNP,TIMM13,PRDX3,IDH3B,PPP1CB,RAB6A,SNX2,ERLIN1,CACYBP,WDR6,THOC2,MYEF2,IGBP1,COPS2,DDX23,TST,PPP3CA,RPL23,PRPF19,EIF3D,WDR11,RBBP7,MCM6,MRPS17,HS2ST1,RFC2,AKT2,MORC2,ARGLU1,PPAN,RBPJ,GTPBP1,TPD52,TXNRD1,E2F4,CYB5R1,GFPT1,NUP153,RAB14,ZNF622,LDHA,YES1,SLC25A4,ARMC6,VKORC1L1,RPL22,STUB1,VAMP3,EIF4A3,CAB39,GANAB,RPS20,CHORDC1,PIP4K2C,NAPA,CA2,KPNA6,PPP1CC,GTF2I,SMC4,HMGB1,PFKFB2,RPL4,POLDIP2,ARPC2,PAK5,LMNA,JUP,OXSR1,EPHX1,RPLP0,MACROH2A2,RBFOX2,PSMC4,RPS14,EEF1E1,ELP3,CNP,EIF2B2,SRPRA,HACD3,SRP14,EHBP1,PWP2,EXOC2,PSMD7,CD9,CALR,ORC5,EMC4,LRRC40,MPG,GLO1,CAMK2G,CTNNBL1,PAK1IP1,THRAP3,RPS13,ARF4,MSH6,PRDX4,NSDHL,PC,SNAP23,PPP4C,TBK1,NECAP2,LBR,EEF1A1,DDX39A,ALG11,BCS1L,UBR7,RPL15,STAT1,TAGLN2,MATR3,TAMM41,ALG5,ACAP2,IRF2,MIDEAS,ZMYM2,SMU1,PRMT5,ADK,CKB,PSMD14,S100A11,RPS26,MDH1,PSMA4,SFN,HNRNPAB,BTF3,STX16,SNRPB,FXR2,TRA2B,NDUFS2,PHB2,PEBP1,DDX39B,DDX5,MAP2K1,AKR1A1,LAP3,ZC3H14,DBR1,HNRNPL,RAB1B,SNRPA1,SNRPD3,OSBP,TRMT61A,CCT7,HSP90AB1,CHMP2A,SIN3A,HDHD5,PRCC,ANXA4,SWAP70,WDR82,FAHD1,AK2,GSTO1,DEGS1,DRG2,CDC23,DDX1,PTDSS1,RAB5C,BTF3L4,DDRGK1,COA1,PSMA2,ROCK2,XPNPEP1,RUVBL1,VAMP8,RPS4X,RAB18,CBLL1,ABCF1,CDK5,PLS3,PTRH2,HEXA,H1-3,RPS7,EIF4H,CHMP5,CDC20,UQCRC2,PSPC1,SRP54,SEC61A1,PITPNB,INTS12,ATP1B3,NIF3L1,CISD1,BICD2,OAT,SORD,UBE2H,SUGP1,RAB2A,RPL7A,CCNB1,CFL1,ST13,HDAC3,STK38,GRPEL1,UGP2,MAIP1,RPL27,SEPTIN6,NBN,PGK1,DERL1,GFM1,DLAT,SSR1,CDC42,CD2AP,CPNE1,MIF,SLC38A2,LMAN1,ALYREF,UBE2N,ADD1,RAP1B,NT5DC1,MTAP,MED27,SMCHD1,AKAP8L,USP3,EDC3,HNRNPK,MEPCE,RPL17,MAP1B,BCAP29,CBX3,ZFP1,CAPN2,GNAI3,NUPR1,ATP5PB,ESS2,GNPNAT1,PRDX2,ACTB,RPF1,MAT2B,CLIC4,ERH,NDUFAF4,USP5,PRRC2A,FAM91A1,SNRPD2,SEC61B,BAX,HSP90AA1,PFDN2,RMI1,ACO2,TMED4,PRPF31,SMARCE1,PAFAH1B2,STX7,PYGB,FBXO30,GSTT2B,PSMA3,CFDP1,USP39,LARP4B,ISOC1,MFAP1,ELOVL1,SNX18,SRSF10,PRKCQ,PPIA,DHX15,RPL8,PSMB5,TYMS,MED4,PDAP1,DICER1,VPS26A,ZNF207,DHX16,ZNF592,S100A10,TMED7,GTF3C3,SACM1L,RAD21,FLOT1,COPS4,HSPD1,HNRNPA2B1,SYPL1,PCNA,GDI2,RAB6B,SNRPE,NAA15,BUD23,PPP2R1A,ERLIN2,PNP,FERMT2,SCML2,CCNF,GXYLT1,GTF2A1,TRIM27,CMBL,RPS12,SFXN2,ODR4,GNPDA1,MSN,ARFGAP3,CDC73,MAPRE1,HERC4,HSPA14,DHPS,ZNF687,RPL26,FBXO7,CTNNBIP1,DNAJC8,RACGAP1,SLC7A1,BRIX1,RDH10,RPA3,HMCES,RTN4,SPCS2,CZIB,PICALM,RARS1,HNRNPH3,SYNGR2,SF3A1,ARHGAP1,UQCRC1,CDK7,CCNA2,RPL35A,COG1,THOC1,TFE3,PTPN1,RPL12,ACTA2,TES,CNN3,SMG9,OSBPL8,MOV10,HM13,ATP1B1,NOC4L,VRK1,FARSA,VTA1,ABHD10,ADD2,VPS16,PPP1R12A,RAB1A,GARRE1,SFXN1,TCOF1,NKRF,RPL23A,LIPA,GINS4,NDUFS3,ACTR2,VAC14,DHRS7B,CMPK1,FBP1,TMEM126A,GBE1,FNTB,PGM1,UBE2V1 |
| 4.851e-47 | -106.64 | RECQL4 (RecQ like helicase 4) | protein interactions | 9401 | 1400 | 636 | 19454 | 5460 |
MRPL49,SRP72,RAD23B,ILF2,MRPL11,RPL15,GGCT,EEF1A1,LBR,CTNNBL1,LSM4,PRDX4,EIF3E,MSH6,CTNND1,OLA1,MRPL22,RPS13,PC,HSD17B10,RING1,PSMD7,DNAJC7,GLO1,HDAC6,EIF2B2,SLC25A12,DBT,POLE3,AIFM1,SRP14,HACD3,SEC23A,FAM199X,HSP90B1,LSM2,MRPS34,LMNA,CDK1,RPLP0,TMOD1,EEF1E1,PSMC4,RPS14,ELP3,FAXC,RPL4,GTF2I,EIF5B,NPM3,MBD3,PRPF4,PNO1,MTDH,PYCR2,SEC13,CDC16,GMPS,PPP1CC,TUFM,KPNA6,NONO,ATP5F1A,RPL13A,SLC25A4,LDHA,TXN,MAGOHB,RPL22,TECR,FBLN5,LURAP1,EIF4A3,STUB1,RPS20,ACAT1,RTRAF,GANAB,VPS33A,GTPBP1,AP2S1,MARCKSL1,KCTD17,RBBP7,TRIM26,G3BP1,RFC3,RFC2,MRPS17,SRSF4,MCM6,NDUFA4,TRIP4,RPS24,FHL3,RPL23,PPP3CA,AHSA1,MRPS35,STOML2,PRDX1,PRPF19,PSMD3,EIF3D,WDR11,ATG7,RPL7,CCAR2,COPS7B,NDUFS8,CACYBP,PHB1,PPP2CB,WDR6,HP1BP3,RPLP1,COPS2,GATD3,PBDC1,ARHGAP25,ADNP,MYL6,PSRC1,WDR77,PRDX3,MCMBP,G3BP2,SKP1,FTL,PSMC1,ATP5MK,NUP50,NUBP2,CCDC86,HADHA,LMNB1,MYO6,NOA1,SP1,CUL3,CUL2,MCM4,MCM3,RIOK2,AK3,RFC5,RBBP4,RPL35,TSN,RPL19,TNPO3,SNRPB2,CHCHD3,PELO,EIF3K,CYB5R3,RAN,ARF1,FAU,RPL37A,LRRC1,NECAP1,RBM34,TFCP2,RNF8,TBC1D4,PSMC3,IPO8,CDK4,ACTR1A,RPAP2,H2AX,TMEM33,KPNA2,SRPRB,CAPZA1,SLC25A11,NOSIP,NAE1,SLC16A1,RPL3,MRPS18B,LANCL2,SNRNP70,TUBG1,USP15,RPL10A,RPS2,PGAM1,KARS1,GPRASP2,CSNK2A1,TMA16,COPS5,RPS16,CDC5L,DKC1,TMPO,NDUFB4,EEF1B2,AIP,SDHB,SYNCRIP,TRAPPC3,ZNF326,CSNK1A1L,WRAP53,RPRD1B,HECTD1,HEXIM1,NTPCR,MRPL10,GTF3C4,MRPL41,RBM22,KDM1A,MARS1,HSPA5,EIF4E,ZC3H15,POLD2,PRDX6,HNRNPH2,EXOSC4,LSM6,DNAJC10,EIF3G,ATP1A1,ANAPC4,MORF4L1,MAT2A,RPS17,PPAT,ADRM1,RPL10L,MRPS21,BUB3,BCCIP,CSTF3,PSMA6,RPS3,MRPS28,EIF2S2,PSMC5,SMNDC1,PNMA2,CRKL,AAMP,RPL18,MTA2,SUPT5H,RANBP1,KIF2A,NUP42,VDAC1,CHCHD2,HNRNPDL,POLDIP3,RPL28,PABPC1,CCT8,RTCB,PDIA6,RUVBL2,RPAP3,EFNB1,DRG1,YWHAB,RIOX2,MRPL9,TCP1,LYAR,EIF2S1,FAM98A,LANCL1,HMG20A,SRSF1,CORO1C,MAGED2,CTBP1,PIH1D1,RPL27A,STAU1,HNRNPA0,MRPS7,RANBP10,SAP18,TRIM52,XRCC5,RFC4,RAB5A,EP300,HSPA8,P4HA2,CHTOP,H1-10,RBBP8,MCAT,DNAJB6,COPS7A,TMED5,PCCB,FBXO22,PSMD6,ATP5F1B,PPP5C,EFHD2,ZNHIT6,ANAPC2,SF3B4,NDUFS3,ACTR2,GINS4,IFT57,DHRS7B,POLR2G,CCT5,EXOSC8,NSMCE3,FARSA,DNAAF10,TTC4,HUWE1,PTGES3,TCOF1,FAF1,RAB1A,INSM2,PPP1R12A,IFT52,RPL23A,KIAA1143,CNN3,TRAPPC4,MOV10,RPL35A,CWC15,MRPS23,MRPL24,CDK9,NCBP2,ACTA2,KRR1,EIF4E2,RPL12,PSMB1,WTAP,HNRNPH3,RPL26L1,RARS1,UBA52,PIP5K1A,SEC22B,WDR5B,SF3A1,PDHB,MRPL17,LSM8,BRIX1,GID8,PRIM2,PPM1G,PPIH,ANAPC16,ASCC1,AP2A1,YPEL5,DHPS,HSPA14,DNAJC8,RPL26,UBE2L3,CTNNA1,ENO1,EIF2AK2,TUBA1B,CTTN,RPS12,NME1,EXOSC3,GDI2,PRKAG1,RPN1,SART3,SNRPE,IFT22,POLR2C,RPS11,ANP32A,HSDL2,FAF2,RPL29,PPP2R1A,ATP5F1D,ASF1A,COPS4,SSRP1,AHCYL1,PSMD12,GTF3C3,HNRNPA2B1,MAEA,HSPD1,SLC25A5,BAG2,SRSF7,MRPS11,PCNA,MRPL18,SKIC8,DICER1,MPHOSPH6,HAX1,HNRNPD,MRPS26,PCNX1,PDIA3,ZNF207,ACTL6B,HNRNPA1,INA,DHX15,STK3,SRSF10,PPIA,PSMB4,PSMB5,RPL8,RPL9,RPLP2,H2AC1,ARMCX3,VPS18,LARP4B,ISOC1,VAPB,PSMB7,SLC25A3,PRSS23,PGRMC1,ACTL6A,RFXANK,AZGP1,CDSN,EXD2,PSMA3,BRCA1,YWHAZ,LSM14B,HTRA2,HSP90AA1,SCFD1,PFDN2,RPS5,PMPCA,PYCR1,RPS29,MRPL16,SMARCE1,MED17,TUBB,ACTB,RANBP6,PRDX2,MRPL23,PRRC2A,MAT2B,FAM91A1,SEC61B,RPS9,SNRPD2,SNRPD1,CAPZA2,EXOC3,CBX3,TP53,RPSA,CSE1L,HNRNPK,MRPS33,PSMA5,RPL17,PSME1,MAP1B,DHX9,CLPB,RPL24,H2AC4,TSNAX,AKAP8L,KPNA1,LSM3,ANKMY2,USP2,API5,GAPDH,ELOC,PPIL4,MIF,RPS27L,CAND1,TMED9,MALSU1,MYL12A,RPL32,ALYREF,MRPS9,SSBP1,MTAP,SSR1,TFB1M,CDC42,RPS15,TUSC2,NBN,MAIP1,RPL27,DLAT,ARFIP1,LSM12,ATP1B3,MRPS16,ALKBH5,IGF2BP1,RPL7A,CCNB1,PSMB2,SMARCA5,CFL1,PRKACB,GRPEL2,RSL24D1,UQCRC2,MACROH2A1,PPP2R5E,PHAX,CSNK2B,SRP54,PTRH2,H2BC1,PDHA1,PLS3,TUBB4B,RPS23,SMARCB1,TRMT1L,EEF2,NUP37,RPS7,TUBA1A,RUVBL1,HNRNPF,PSMA2,PSMA1,PRPS1,RPS4X,LSM14A,ABCF1,FBXO3,RPL31,EWSR1,ARMC8,DDX1,CDC23,RAB5C,WWP2,RPL6,PTDSS1,QPCTL,ACTR3B,YWHAH,XPO1,YWHAG,AASDHPPT,SNRPA1,SNRPD3,NOB1,DBR1,RPS10,HNRNPL,HSP90AB1,CCT7,GYS1,HDHD5,FUBP3,PSME2,RPRD1A,WDR82,GSTM2,TRMT112,EIF4B,PSMB3,EEF1G,PHB2,NDUFS2,TRA2B,GINS3,RPS28,SPECC1L,DDX39B,DDX5,SF3B1,H2AZ2,MRPS25,PSMD14,CCT2,CKB,CIRBP,SERPINH1,RCL1,H1-1,RPS26,HNRNPAB,SFN,PSMA4,LDHB,CHST9,HNRNPC,MYC,UFD1,DRAP1,SNRPB,CPSF2,PSMD1,MATR3,KBTBD6,RPL10,POLR2B,PSMB6,DLST,VDAC2,MRPL13,PRMT5,SMU1,DKK3,TRMT11 |
| 1.249e-46 | -105.70 | PLEKHA4 (pleckstrin homology domain containing A4) | protein interactions | 57664 | 2955 | 1160 | 19454 | 5460 |
CBX3,MVD,ATP5PB,KIF1C,RPL17,SCML1,HNRNPK,MAP1B,MYD88,PSME1,SMG8,AKAP8L,ATP6V1D,SMCHD1,TMEM70,ROGDI,EDC3,SLC38A2,LMAN1,RPS27L,ADD1,DSTN,MTAP,ALYREF,UBE2G2,SUPT7L,HPS6,DDX4,CDC42,CD2AP,WDR55,UGP2,GRPEL1,RPS15,STK38,FTSJ1,PGK1,LSM12,GFM1,SMG5,DLAT,MAIP1,RPL27,TMEM263,TRIM3,NBN,PML,OAT,EXOSC1,RBM7,SORD,ATP1B3,MRPS16,CISD1,CFL1,PHKA1,TMEM41A,TRIM32,RAB2A,CCNB1,CDC20,PITPNB,SEC61A1,PTPMT1,INTS12,PSPC1,UQCRC2,SMARCB1,PLS3,H1-3,NUP37,RPS7,RPS4X,RAB18,TFG,CBLL1,PSMA2,ROCK2,RUVBL1,CDK5,ABCF1,LSM14A,CDC23,DDX1,MGMT,H2BC17,YWHAG,NDUFV2,CTNNB1,RAB5C,WWP2,CCT7,HSP90AB1,RAB1B,HNRNPL,ECHDC1,SNRPA1,SNRPD3,OSBP,WDR82,FAHD1,SIN3A,RAB31,HDHD5,PRCC,MAP2K1,MRPL12,SYK,ZC3H14,ARMCX2,TRA2B,FXR2,NDUFS2,BOLA2B,PHB2,DDX5,SMARCD3,CRMP1,RPS26,MDH1,CKB,PSMD14,MRPS25,SLC1A3,PSMA4,HNRNPAB,PSMB6,ALG5,STAT1,TAMM41,TAGLN2,ZMYM2,PRMT5,RRAS2,RETREG3,VAC14,DHRS7B,NDUFS3,ACTR2,CMPK1,TMEM126A,NDUFA2,FASTKD5,RIGI,VPS16,NOC4L,FARSA,VRK1,PPP1R12A,RAB1A,SFXN1,NKRF,SMG9,CNN3,OSBPL8,HM13,ATP1B1,ERCC3,MOV10,NCBP2,MRPL24,RPL35A,COG1,THOC1,TES,RB1,PTPN1,SMAD3,RPL12,CARHSP1,RARS1,HNRNPH3,DCTN4,CHMP1A,GOLGA5,PICALM,UQCRC1,SLC35E1,RABL3,SF3A1,CHMP2B,BRIX1,KIN,CDC73,SMAD2,MAPRE1,SDF2L1,RPL26,HMOX2,RACGAP1,HSPA14,CIAO1,SCML2,UBB,CEP97,COPE,RPP25L,TRIM27,CMBL,RPS12,SFXN2,GNPDA1,ALB,CTU1,POP7,DOHH,CTNNA2,NDUFS6,GDI2,RAB6B,PPP2R1A,ERLIN2,NAA15,MACO1,RAF1,GTF3C3,SACM1L,RAD21,COPS4,FLOT1,DHX16,ZNF592,HECTD3,PRPSAP1,HSPD1,HNRNPA2B1,VPS4A,DICER1,PDAP1,ACTL6B,ATG9A,BABAM1,PPP2R5A,VPS26A,PPIA,PRKCQ,SLMAP,DHX15,RPLP2,RPL8,PSMB5,ELOVL1,FOXS1,ISOC1,LARP4B,ARMCX3,ACTL6A,TOR1AIP2,CSRP1,PYGB,GSTT2B,ATP6V1G1,NOP53,ZFP64,PSMA3,EXD2,PFDN2,HSP90AA1,PRPF31,SMARCE1,MTG2,MAT2B,NDUFAF4,PRRC2A,USP5,IP6K1,PRDX2,TAB1,SNRPD2,SEC61B,GPR89A,FAM91A1,RAB28,GFM2,SESN2,TBC1D4,TFRC,TMEM165,ZMYM3,RRM1,NAA35,MRPL47,CAPZA1,FKBP8,CDC40,SRPRB,ERO1A,STX18,RAB13,MRPS18B,TRAFD1,SLC25A11,RPS2,CDK12,USP15,SMAD4,LANCL2,GPRASP2,KARS1,RBM17,PGAM1,RBM42,IAH1,TMPO,MIOS,ARL6IP5,RPS16,GTF2B,COQ8A,STT3A,ARMC1,COMT,ARL15,HEXIM1,ACACA,RPRD1B,RPA2,EIF2B3,USE1,TRAM1,SLC35F6,UPRT,EIF4E,MARS1,NAPG,RBM22,CWF19L1,HNRNPH2,EXOSC4,LCP1,TMX2,UGDH,RAP2C,DNAJC10,EXOC5,RPS17,TYW3,BCCIP,BUB3,PPAT,PSMC5,GTF2H2,RPS3,LIG3,ATL1,ZBTB33,ZRANB2,RPL18,AAMP,CRKL,KLHL12,UCK2,SMNDC1,TRAF2,UBL5,ARFGEF1,SUPT5H,RANBP1,DNAJB4,ACTR1B,RTCB,TOP2B,CCT8,DRG1,NDUFB8,HSPB1,CNOT8,MRPL9,IQSEC1,UTP6,RMND1,DYNC1I2,MAGED2,DIPK2A,TRAPPC10,SRSF1,CTBP1,SEC22A,NEK7,RALYL,LDAH,SLC16A10,SHMT1,PAFAH1B1,EHHADH,MRPS7,SELENOO,EMC1,OXCT1,RER1,RAB5A,SNRPA,OSGEP,MCAT,THOC6,H1-10,FTSJ3,COX11,COPS7A,PPP5C,MORC4,ATP5F1B,TIMM21,SNRNP40,FAM83B,SF3B4,GTF2F1,PPP4C,POMT2,MRPL49,NECAP2,DDX39A,EEF1A1,LBR,UBR7,PGM2L1,RPL15,MTA3,TBK1,COMTD1,MRPL11,RPS13,ARF4,MSH6,PRDX4,CAMK2G,THRAP3,PC,SNAP23,NSDHL,ZNF787,KATNAL1,CRBN,EXOC2,PSMD7,LRRC40,MFN1,APOBEC3F,TMEM199,ORC5,EMC4,TLE1,GMPPA,NAA11,ATP5PD,KCTD15,EIF2B2,PWP2,SRPRA,SRP14,HACD3,OXSR1,ZNF574,TM9SF1,RPLP0,MACROH2A2,MRPS34,LMNA,JUP,SIPA1L1,CNP,ELP3,RBFOX2,PSMC4,CPSF4,EEF1E1,MBD3,POLDIP2,NPM3,GTF2I,SMC4,RPL4,PRPF4,CASC3,CHORDC1,DCAF16,DEPDC1B,KPNA6,PPP1CC,CDC16,PYCR2,RPL22,SMAD5,ZNF622,LDHA,SLC25A4,ARMC6,DTYMK,GANAB,WDR45,CHCHD6,UBE2I,STUB1,EIF4A3,SCAMP2,GNB1L,GTPBP1,VPS33A,OXNAD1,NUP153,YIPF3,GFPT1,SAP30,TXNRD1,MRPS17,MCM6,RFC2,RBBP7,ZC3H7A,SRSF8,TRIP4,AKT2,PPP3CA,RPL23,DDX23,EIF3D,TRA2A,WDR11,PRPF19,CLPX,SAV1,ERLIN1,CACYBP,NDUFS8,SNX2,BUD31,PBDC1,WDR6,CBFB,THOC2,PPP2CB,MED23,ATP5PO,APOBEC3C,ADNP,RNF7,PRDX3,PPP1CB,IDH3B,RAB6A,GK2,PRKAB1,WDR77,COIL,SKP1,MCMBP,HADHA,COMMD2,NUP50,RTKN,TMEM168,SP1,EXOC8,ELMO2,BLVRA,ATP1A3,LMNB1,RNF40,RHEB,TOMM40,MCM4,CUL2,MRM2,CHCHD3,SNRPB2,TNPO3,GNB1,DYNLL1,TSN,RPL35,UMPS,CDC7,UBE2S,PIGK,PELO,SLC25A24,DDX42,CAPZA2,SPRR1B,METTL15,TP53,RDH11,SLC25A14,LPCAT3,PSMA5,NUP107,AKAP12,RAB3B,CSE1L,CLPB,DHX9,TAF9,KPNA1,MAP4,SHC1,RPL24,PPIL4,TPM3,ELOC,LYPLAL1,GAPDH,CAND1,TMED9,KCTD3,MRPS9,SSBP1,ACSL4,RPL32,TFIP11,LUC7L3,CSNK1G3,LEMD3,WWP1,WDR3,TEX264,DDX46,NLE1,DTL,IGF2BP1,CDKN2AIP,ENDOD1,PRKACB,CFL2,SMARCA5,CARS1,SLC25A1,AKT1,DYRK1A,DAPK3,IRF2BP1,CSNK2B,MACROH2A1,SF3B6,ALG2,NDUFA12,APTX,RPS23,PDHA1,TUBA1A,EEF2,SPC24,TRMT1L,DHX38,ETFB,DCTPP1,CCAR1,PRPS1,UTP25,USP30,PSMA1,DCP2,HNRNPF,EWSR1,MYO1B,FBXO3,RPL31,CRTAP,XPO1,YWHAH,NGDN,EXOC1,DDX50,BAZ1B,SEC61A2,RPL6,PEG10,PEX13,RPS10,NOB1,ZNF740,SUMO3,PABPC1L,STX5,RPRD1A,FUBP3,GYS1,NUFIP2,EIF4B,TRMT112,CNDP2,LMBRD2,ACAA2,QTRT2,TOMM22,PSMB3,LYPLA2,SLC37A4,TIMM17A,UFL1,EEF1G,GPHN,SF3B1,RAMAC,ACTMAP,TIMP3,ZMPSTE24,SERPINH1,RCL1,CCT2,FBXW11,H2AZ2,RPS6KA4,PSMD1,RMI2,CPSF2,UFD1,HNRNPC,LDHB,POLR2B,LRIF1,NCKAP1,STAT2,HDDC2,MRPL13,VDAC2,KTI12,MMACHC,MAP2K3,CD2BP2,EXOSC8,CCT5,PSEN1,PTGES3,H2AC6,HUWE1,FN3KRP,TTC4,KLHL15,TRAPPC1,MUL1,PMM2,NKIRAS2,MSMO1,DERL2,PSMB1,COX20,RLIG1,EIF4E2,KRR1,STAMBP,WTAP,SLC12A2,STOM,COQ8B,TIMMDC1,SEC22B,UBA52,VPS28,MRPL17,PDHB,PRKCB,DVL2,HELLS,PPM1G,PRIM2,SOD1,IDH3A,AP2A1,GGCX,ASCC1,GMNN,TAF5L,UBE2L3,DEK,GNAI2,VIRMA,TMOD3,MRPL53,CTTN,CTNNA1,EIF2AK2,ENO1,RPS11,UCKL1,POLR2C,STX12,JPT2,SKA3,RPN1,PRKAG1,BZW2,EXOSC3,ACTN4,FAF2,HSDL2,RPS27A,PSMD12,SSRP1,ATP5F1D,FAM76B,SRSF7,BAG2,SLC25A5,NEK9,SCYL2,GPAA1,ZYX,HNRNPD,HAX1,WDR12,SKIC8,HNRNPA1,PIK3R1,PDIA3,RAB32,MAP1S,NDC80,NUP35,STK3,NUF2,INA,AGK,ATP6V1A,RPL9,MRTO4,ARCN1,SLC25A3,KCTD12,VAPB,VPS18,RRAGA,ASRGL1,PGRMC1,CYFIP2,YTHDF1,SRM,HSDL1,ATP2C1,PRKD3,DNAJC3,SNRK,RPS5,SCFD1,HTRA2,ARMT1,ILK,FYTTD1,YWHAZ,MRPL16,RPS29,PKP4,RAB11A,PMPCA,LIN7B,ABHD12,MRPL23,RANBP6,TUBB,POLR3B,RPS9,PSMC3,CHAMP1,GPD2,ARPC3,ACADSB,RBM34,DNAJC2,ACTR1A,ZMYM4,PREB,IPO8,KPNA2,ABCE1,SLC16A1,MAN1A2,IDH1,NAE1,RUSF1,NOSIP,ATP2B4,RPL10A,TUBG1,SNRNP70,BECN1,TMA16,CSNK2A1,TSEN34,ACOT8,CMSS1,RBFOX3,ZNF24,ILVBL,CDC5L,SLAIN2,VPS26C,SYNCRIP,AIP,NDUFB4,GIT2,PRKCA,UTP15,UBE2M,VPS4B,ZNF326,VIPAS39,SAMM50,IDH2,NDUFAB1,GTF3C4,NTPCR,SPTBN1,AKR7A2,SUMO1,ZC3H15,HSPA5,KDM1A,MRPL41,RAB9A,PRDX6,RNF113A,THUMPD1,POLD2,ATP1A1,SERPINB1,RRP7A,EIF3G,H2BC9,NCAPG2,MAT2A,GSTK1,PTPN11,ROCK1,PPP1R10,CSTF3,DUSP3,PYGM,GPX1,RPL10L,GMDS,ADRM1,EIF2S2,PSMA6,MTA2,STMN2,TNPO2,KIF2A,CSTF2T,NAA16,TOP3B,RPL28,POLDIP3,HNRNPDL,VDAC1,RUVBL2,GALC,PDIA6,RINT1,PABPC1,YWHAB,IKBKB,FKBP4,TBC1D5,STK4,LANCL1,MEAF6,FAM98A,EIF2S1,LYAR,TCP1,EED,CORO1C,PTK7,TNIK,KLC2,NCOA5,MRPS18A,SIGMAR1,UBAC2,ZNF362,YIPF5,RPL27A,NUP62,RANBP10,RNF41,HNRNPA0,UBE2D3,SSR3,PITHD1,STAU1,HSPA8,STK26,AKAP1,RFC4,XRCC5,NSA2,THTPA,GTPBP2,DNAJB6,CHTOP,RBM27,RPL39,HMGCS1,ISCA2,PAPOLA,ATP6AP2,USP16,PSMD4,PSMD6,DYNLRB2,GTF2F2,PHKB,ANAPC2,TACO1,EFHD2,ZNHIT6,ILF2,SRP72,DMAP1,PPIF,GGCT,CCDC47,YTHDF2,RNF20,CTNND1,EIF3E,MDC1,RING1,SEPTIN7,EMC2,HSD17B10,TMX3,EHD4,SLC25A10,GLUL,DNAJC7,TOPBP1,SLC2A1,ESYT1,EI24,ISYNA1,NOP9,SLC25A12,ARF6,TOP1,POLR2I,EIF2B5,MAPRE2,HSD17B11,SEC23A,H2AZ1,AIFM1,CTDSPL2,MAP2K6,TTI2,PTP4A2,TOX4,CDK1,P3H1,H2AC7,HSP90B1,HACD2,EHD3,MYL12B,SNRPN,AATF,CERS2,GPX4,MTDH,PNO1,FADS2,CSTB,XPOT,STK24,ATP5F1A,NONO,USP14,GMPS,TUFM,CSK,NDUFB10,RETSAT,SEC13,TECR,SEC63,TXN,PRKRA,GSK3A,RTRAF,ACAT1,TRIM24,PELP1,SF3B5,RNF126,OTULIN,EZH2,WDR37,FEN1,TMT1B,RFC3,G3BP1,PCGF3,LASP1,ETFA,GNL1,RPS24,UBE3A,NDUFA4,TMT1A,SLC25A21,AHSA1,RHOG,PSMD10,PSMD3,PRDX1,STOML2,MRPS35,MARCHF5,LRWD1,KIF3B,NOP58,MPP1,ATXN10,SNX1,CCAR2,SPTAN1,XPO5,TSG101,GATD3,HP1BP3,DNM2,OCIAD2,PHB1,MYL6,VAV2,NRDE2,EHD1,TIMM29,ETF1,MTX2,PSMC1,POLA2,UNC45A,TSR3,ATAD1,TRUB1,CCDC86,NUBP2,UPF3B,CBR3,MYO6,NOA1,RFC5,RIOK2,SAMHD1,MCM3,NDUFB6,CUL3,MAD2L1,RPL19,PARL,RBBP4,RPL7L1,SPINDOC,AP2M1,RPL37A,SARM1,FAU,ARF1,CPSF1,EIF3K |
| 1.763e-46 | -105.35 | RPA1 (replication protein A1) | protein interactions | 6117 | 3034 | 1185 | 19454 | 5460 |
GNPAT,XXYLT1,RPL32,ACSL4,SSBP1,MRPS9,ESD,R3HCC1,KCTD3,CAND1,TMED9,GAPDH,ELOC,API5,PPIL4,ANKMY2,MTMR12,DPP4,MAP4,TRMT5,TAF9,KPNA1,RPL24,H2AC4,DHX9,CLPB,RDH11,CTSC,LPCAT3,CSE1L,MRPS33,NUP107,NEDD8,H3C1,PDE12,APOO,FAM162A,RPSA,TP53,STRBP,FURIN,SLC25A24,RAD1,CAPZA2,SURF4,DDX42,PPP2R5E,MACROH2A1,CSNK2B,PHAX,SF3B6,CDIPT,RNASEH1,SMARCA5,AKT1,PSMB2,CARS1,SLC25A1,CDKN2AIP,IGF2BP1,PDCD4,NLE1,DDX46,BAP1,WDR3,LUC7L3,CYC1,LEMD3,TFIP11,DYRK2,STX5,FUBP3,GYS1,RAB35,AASDHPPT,RPS10,NOB1,EXOC1,NGDN,DNTTIP1,XPO1,YWHAH,PFDN5,RPL6,DDX50,DDT,UBFD1,CRTAP,ARHGAP5,EWSR1,MYO1B,GNA11,RAB8B,PRPS1,UTP25,CCAR1,PSMA1,HNRNPF,EEF2,DHX38,GCLC,ETFB,TRMT1L,DCUN1D5,RPS23,GNAQ,PDHA1,TUBB4B,MCPH1,TRMT11,CMTR1,DLST,VDAC2,NCKAP1,APEX1,ESR2,CBX5,LRIF1,POLR2B,SSH3,BAG3,ATG101,HNRNPC,LDHB,MYC,ZMPSTE24,RCL1,SERPINH1,H2AZ2,CCT2,SF3B1,JAGN1,NANP,LYPLA2,SLC37A4,EEF1G,UFL1,SEC62,QTRT2,PSMB3,ATP6V1C1,MTMR6,TOMM22,CSNK1A1,CNDP2,NUFIP2,EIF4B,PSMB1,COX20,CHID1,EIF4E2,KRR1,WDCP,RLIG1,CDK9,TOMM70,DCUN1D1,ATP5MG,FAF1,SMN1,FN3KRP,HUWE1,CNOT7,NRM,EXOSC8,MAP2K3,CD2BP2,CCT5,CTTN,CTNNA1,ENO1,EIF2AK2,DEK,PDCD5,VIRMA,UQCRQ,CPT2,TMOD3,NDN,MGST3,BRAP,GGCX,DNAJC19,AP2A1,NDUFC2,IDH3A,HELLS,DVL2,PRIM2,INPPL1,PPM1G,DAD1,PDHB,YKT6,UBLCP1,TIMMDC1,SEC22B,COX6C,BRD9,ATP6V1A,SNX17,MRTO4,RPL9,NUF2,HNRNPA1,MAP1S,NDC80,PDIA3,RAB32,COTL1,RB1CC1,UCK1,HAX1,HNRNPD,DROSHA,WDR12,CDK5RAP3,MRPS11,BAG2,SLC25A5,NEK9,SCYL2,ZYX,NUDT5,GPAA1,AHCYL1,SSRP1,FANCG,PSMD12,RPL29,ACTN4,JUN,FAF2,HSDL2,DCAKD,ANP32A,ARFGAP1,RBM12,JPT2,SART3,RPS11,STX12,RIMOC1,PRKAG1,BZW2,EXOSC3,CHMP4C,RPN1,RPS9,SNRPD1,POLR3B,RSRC1,TRMT6,ABHD12,REEP4,TUBB,EIF4A2,ELMOD2,MRPL16,JPT1,RAB11A,TM9SF4,CDC123,ZNF250,ARMT1,ILK,RPS5,SCFD1,YWHAZ,BRCA1,EMG1,TXNL1,RABAC1,TBC1D24,CMAS,YTHDF1,RADX,SRM,CYFIP2,STXBP1,PGRMC1,RRAGA,ARCN1,ANXA7,SLC25A3,FKBP1A,KCTD12,VAPB,AKR1B1,PREP,NDUFB4,COX4I1,SYNCRIP,CDC5L,SURF6,SELENOI,ILVBL,VPS26C,CSNK2A1,CMSS1,AGPAT1,RPL10A,PSMG2,TUBG1,THG1L,IDH1,ABCE1,SLC16A1,RPL3,NAE1,NOSIP,MNAT1,KPNA2,ZMYM4,H2AX,HADH,ACTR1A,CDK4,IPO8,TNRC6C,PREB,PSMC3,ARPC3,DNAJC2,IK,CHAMP1,GPD2,STX10,EIF2S2,PPP1R10,CSTF3,RPL10L,GMDS,RALA,NCAPG2,GSTK1,PTPN11,SUB1,RPF2,NAA50,MAT2A,SNX5,ATP1A1,SERPINB1,EIF3G,CRLF3,SPOP,PRDX6,RNF113A,THUMPD1,POLD2,APMAP,ORC6,HSPA5,TOMM20,KDM1A,UBE2K,NTPCR,TRMT13,CCNH,SUMO1,SPTBN1,PRKCA,UTP15,UBE2M,VIPAS39,SAMM50,IDH2,RFX5,EED,CORO1C,TNIK,LANCL1,LYAR,TCP1,FAM98A,EIF2S1,TBC1D5,GSTM3,YWHAB,FKBP4,PDIA6,RUVBL2,RPAP3,RBM3,PABPC1,NDUFB5,HNRNPDL,POLDIP3,RPL28,VDAC1,TNPO2,KIF2A,CSTF2T,CCDC134,TOP3B,MTA2,SEC61G,GTF2F2,PHF21A,EFHD2,PSMD6,FBXO22,PSMD4,HMGCS1,PAPOLA,NSA2,CHTOP,RBM27,SPCS3,AKAP1,STK26,HSPA8,XRCC5,RFC4,SLU7,SSR3,STAU1,HNRNPA0,NUP62,RPL27A,SIGMAR1,UBAC2,PAK2,SEC23A,HSD17B11,AIFM1,G6PD,NOP9,CAV1,SLC25A12,TOP1,MAPRE2,EIF2B5,ARF6,HDAC6,ISYNA1,TOPBP1,DNAJC7,ESYT1,SLC2A1,TTL,EMC2,HINT1,TMX3,ZC3H11A,SEPTIN7,EHD4,EIF3E,GALNT2,MDC1,OLA1,CTNND1,POLL,LSM4,SEM1,AGPAT5,GGCT,MAP1LC3B,YTHDF2,CCDC47,SRP72,RAD23B,CASK,ILF2,PPME1,UAP1,ACAT1,GSK3A,RTRAF,PRKRA,CYRIB,PELP1,SELENOT,SEC63,ZNF507,TECR,RPL13A,TXN,AR,NONO,GMPS,USP14,TUFM,ATP5F1A,RUNX1,SEC13,CSK,CTSD,XPOT,STK24,TADA3,CCDC22,TDP1,SQSTM1,MAVS,MTDH,PNO1,NCDN,TMEM209,CRYZ,GABARAP,AATF,USP8,NUCKS1,EIF5B,EIF3J,EDF1,SPR,SAP30BP,ATG16L1,PITPNA,IFRD1,GHITM,TOX4,TIMM23,CDK1,HP1BP3,XPO5,OCIAD2,PHB1,DNM2,LRWD1,RAB11B,NTMT1,ATXN10,MPP1,SPTAN1,SNX1,CCAR2,RPL7,COPS7B,OCRL,NOP58,STOML2,MRPS35,MARCHF5,PSMD3,PRDX1,LYZ,PDCD10,SLC25A21,AHSA1,RHOG,RPS24,UBE3A,NDUFA4,TMT1A,ANP32B,RFC3,PPWD1,AP1M1,GNL1,G3BP1,FEN1,AP2S1,CYB5B,PLD3,PGGT1B,STIM1,RMDN3,AP2M1,RPL37A,SLC30A7,EIF3K,CYB5R3,CPSF1,ARF1,RPL19,MAD2L1,RPL7L1,RBBP4,MCM3,RFC5,SAMHD1,CFAP20,CUL3,KDSR,USP13,NDUFB6,MYO6,ATP5F1E,ATP5MK,UNC45A,PSMC1,POLA2,NSFL1C,ATAD1,NPTN,TIMM29,ETF1,MTX2,FAM3C,VAV2,NT5DC1,MTAP,ADD1,RAP1B,ALYREF,UBE2N,SLC38A2,LMAN1,MIF,VTI1B,CPNE1,RPAIN,CD81,SMG8,AKAP8L,TMEM70,SMCHD1,MED27,BCAP29,ZNF451,PSME1,MAP1B,RPL17,MEPCE,HNRNPK,RPIA,GNPNAT1,ESS2,ATP5PB,MVD,GNAI3,NUPR1,CAPN2,CBX3,INTS12,SRP54,PITPNB,SEC61A1,PSPC1,UQCRC2,PLEKHF1,CDC20,CHMP5,EIF4H,ST13,CFL1,RPL7A,CCNB1,SUGP1,RAB2A,UBE2H,SORD,OAT,BICD2,ATP1B3,CISD1,GFM1,DERL1,DLAT,PGK1,MAPKAPK3,NBN,MAIP1,RBM23,RPL27,SEPTIN6,UGP2,GRPEL1,STK38,CDC42,CD2AP,GTF2H4,FGFR1,SSR1,WDR82,HDHD5,ANXA4,SWAP70,PRCC,SIN3A,CCT7,HSP90AB1,TRMT61A,SNRPD3,OSBP,RAB1B,DBR1,HNRNPL,DDRGK1,BTF3L4,CTNNB1,YWHAG,PTDSS1,RAB5C,IFI16,ARMC8,CDC23,PEX3,CBL,DDX1,DRG2,AK2,GSTO1,DEGS1,CDK5,ABCF1,RAB18,CBLL1,RPS4X,VAMP8,XPNPEP1,RUVBL1,PSMA2,COA1,RPS7,NCSTN,H1-3,MOB3C,PLS3,ZMYM2,SMU1,PRMT5,MIDEAS,IRF2,PAPSS2,ALG5,PSMB6,TAX1BP1,STAT1,MATR3,TAMM41,TAGLN2,SNRPB,STX16,BTF3,PSMA4,SFN,HNRNPAB,COX6B1,MDH1,RPS26,S100A11,PSMD14,ADK,CKB,KIAA1191,DDX5,PEBP1,DDX39B,CERS6,PHB2,FXR2,NDUFS2,ZC3H14,AKR1A1,MAP2K1,TES,NAA30,RB1,MYBL2,ACTA2,EFNA3,PTPN1,SMAD3,RPL12,MRPL24,THOC1,COG1,RPL35A,ATP1B1,HM13,ERCC3,MOV10,OSBPL8,CNN3,SMG9,LIPA,RPL23A,SFXN1,TCOF1,NKRF,PPP1R12A,RAB1A,ABHD10,ADD2,VPS16,FASTKD5,VTA1,NOC4L,VRK1,FARSA,PGM1,UBE2V1,GBE1,FBP1,TMEM126A,DHRS7B,VAC14,ACTR2,GINS4,SFXN2,RPS12,MSN,GNPDA1,CMBL,GTF2A1,CCNF,GXYLT1,SCML2,PNP,RACGAP1,FBXO7,RPL26,ZNF687,STK38L,MAPRE1,CDC73,ARFGAP3,RTN4,SPCS2,KIN,RDH10,RPA3,BRIX1,SLC7A1,NF2,CCNA2,CDK7,UQCRC1,ARHGAP1,SYNGR2,SF3A1,RARS1,HNRNPH3,METTL14,CZIB,PICALM,DCTN4,TYMS,PSMB5,RPL8,WDR44,DHX15,PPIA,SRSF10,SNX18,ZNF207,VPS26A,PDAP1,DICER1,MED4,PPM1B,PCNA,SYPL1,HNRNPA2B1,HSPD1,SACM1L,RAD21,COPS4,FLOT1,TMED7,GTF3C3,ZNF592,DHX16,ERLIN2,PPP2R1A,CSNK1E,NAA15,BUD23,RAF1,SNRPE,RAB6B,GDI2,SEC61B,SNRPD2,ERH,CLIC4,NDUFAF4,PRRC2A,MAT2B,ACTB,RPF1,PRDX2,PRPF31,SMARCE1,TMED4,ACO2,RMI1,BAX,PFDN2,HSP90AA1,PSMA3,CFDP1,EXD2,FBXO30,GSTT2B,STX7,PYGB,PAFAH1B2,MFAP1,ELOVL1,ISOC1,ARMCX3,USP39,PSMB7,TRAPPC3,ARMC1,COMT,EEF1B2,GTF2B,STT3A,COQ8A,RBM42,TMPO,DKC1,RPS16,ARL6IP5,IFRD2,COPS5,RBM17,PGAM1,KARS1,RPS2,CDK12,SMAD4,ERO1A,STX18,RAB13,TCEA2,SLC25A11,CAPZA1,FKBP8,SRPRB,TMEM33,CDC40,KDM4B,TMEM205,ZMYM3,WBP11,MTCH2,RRM1,SESN2,TBC1D4,TFCP2,TFRC,PSMC5,MOB4,GCFC2,LIG3,ZBTB33,RPS3,ACOX1,SRC,BCCIP,SRPK2,GABPA,PPAT,BUB3,EXOC5,RPS17,MORF4L1,DNAJC10,LCP1,CWF19L1,TMX2,UGDH,MARS1,RBM22,SETD3,CAPN1,HECTD1,ACACA,EIF2B3,RPRD1B,CSNK1A1L,RPA2,MAGED2,MPDU1,MACROD1,VAMP7,TOR1B,TMEM97,TRIR,PAIP1,NT5C2,UTP6,PPIB,DRG1,HSPB1,ACTR1B,RTCB,PICK1,RABGGTB,TOP2B,CCT8,NUP42,SATB1,KRAS,SOX2,RANBP1,SUPT5H,RPL18,CRKL,ZRANB2,RAB4A,UCK2,SMNDC1,NUDT19,GTF2F1,PPP5C,TIMM21,SNRNP40,ATP5F1B,COPS7A,THOC6,MCAT,POLR1B,OSGEP,H1-10,FTSJ3,LAMTOR1,RAB5A,EP300,SNRPA,HIRA,MRPS7,RER1,PRCP,EMC1,NEK7,SHMT1,GOSR2,FDFT1,CTBP1,PLAA,ADSS2,PWP2,SRP14,HACD3,SRPRA,PLGRKT,POLE3,AKAP17A,SLC25A17,EIF2B2,LRRC40,MPG,GLO1,EMC4,CALR,ORC5,SSX2IP,PSMD7,EXOC2,CD9,PC,SNAP23,NSDHL,MSH6,PRDX4,RPS13,ARF4,THRAP3,CAMK2G,PAK1IP1,CTNNBL1,BCS1L,UBR7,RPL15,DDX39A,LBR,EEF1A1,TBK1,PPP4C,RPS20,PTEN,CAB39,GANAB,EIF4A3,STUB1,QNG1,VAMP3,OPTN,RPL22,SMAD5,VKORC1L1,DYNLT3,SLC25A4,YES1,RAB14,LDHA,ZNF622,PPP1CC,AAMDC,NAPA,EPHA2,CA2,CHORDC1,ARPC2,POLDIP2,SMC4,HMGB1,RPL4,DGCR8,GTF2I,CNP,ELP3,EEF1E1,RPS14,RBFOX2,PSMC4,MACROH2A2,OXSR1,RPLP0,EPHX1,MRPS34,JUP,LMNA,COPS2,IGBP1,CCDC127,WDR6,THOC2,ERLIN1,CACYBP,KCTD10,BUD31,SNX2,WDR11,EIF3D,PRPF19,PPP3CA,RPL23,TST,DDX23,ZC3H7A,ARGLU1,PPAN,AKT2,TRIP4,MORC2,HS2ST1,RFC2,MCM6,ZBTB14,RBBP7,GFPT1,CYB5R1,NUP153,TXNRD1,TPD52,CPE,GTPBP1,RBPJ,VPS33A,UBE2S,RAN,PIGK,GNB1,TNPO3,SNRPB2,TSN,RPL35,UMPS,DYNLL1,MB21D2,GGH,MCM4,TOMM40,RHEB,CUL2,EXOC8,SP1,LMNB1,ELMO2,BLVRA,HADHA,TTC1,NUP50,RTKN,SKP1,NT5C3A,COIL,MCMBP,RAB6A,PRDX3,PPP1CB,IDH3B,ADNP,MED23,APOBEC3C |
| 4.320e-46 | -104.46 | ORF1ab (ORF1a polyprotein;ORF1ab polyprotein) | protein interactions | 43740578 | 3416 | 1306 | 19454 | 5460 |
ZC3H7A,PPAN,ARGLU1,PLSCR1,TRIP4,HS2ST1,MCM6,KCTD17,EMC8,RBBP7,GTF2E2,YIPF3,CYB5R1,EMC10,KHDC4,RBPJ,GPBP1L1,CYB5A,IGBP1,WDR6,THOC2,CETN2,ERLIN1,CACYBP,NDUFS8,SNX2,BUD31,POLR3F,TRA2A,FEM1B,EIF3D,SAV1,TMEM208,TAF7,CLPX,RPL23,C2CD2L,TST,TTC1,HADHA,DCTN3,COMMD2,ATP5IF1,TSPAN15,THOC3,GPM6A,MCMBP,RAB6A,TIMM13,PRDX3,IDH3B,PPP1CB,LNX2,WDR77,ASZ1,RTF2,ADNP,ATP5PO,MED23,RAN,UBE2S,PELO,PIGK,SNRPB2,GNB1,TNPO3,CHP1,CHCHD3,RPL35,DYNLL1,TSN,UMPS,GGH,TTC23,MCM4,RNF40,TOMM40,PROX1,CUL2,NOP16,NDUFB7,EXOC8,SP1,LMNB1,BLVRA,ELMO2,PC,SNAP23,TTPAL,DLG1,NSDHL,STX8,MSH6,PRDX4,RPS13,VWF,CNOT6L,TICAM1,ARF4,THRAP3,TF,RPL15,NECAP2,LBR,EEF1A1,ALG11,DDX39A,MRPL11,COMTD1,TBK1,CDCA3,PWP2,RCHY1,HACD3,SRP14,SRPRA,POLE3,ATP5PD,RGS10,EIF2B2,PPP1R18,GLO1,EMC4,TLE1,BAK1,CALR,TMEM199,KLHL9,SSX2IP,PSMD7,MPHOSPH10,H2BC12,ARPC2,ORMDL1,SS18,ATG4C,MBD3,NHP2,SMC4,RPL4,ELP3,CNP,SIPA1L1,COMMD3,EEF1E1,CCND1,RBFOX2,PSMC4,MACROH2A2,TMOD1,OXSR1,PDCL,RPLP0,LMNA,JUP,RPS20,CFAP298,GANAB,EIF4A3,GUCY1B1,SCAMP2,STUB1,OPTN,VKORC1L1,ARMC6,SNX3,YES1,RAB14,LDHA,PPP1CC,PYCR2,CAP2,CASC3,NAPA,PIP4K2C,LGALS8,IVNS1ABP,TMEM106C,ACTR1B,RTCB,DNAJB4,CCT8,RWDD4,NUP42,ISG15,CRTC2,TRAF2,RANBP1,ARFGEF1,NETO2,MAX,AAMP,CRKL,UCK2,SMNDC1,RAB4A,KDELR1,NUDT19,HEBP1,MAGED2,SRSF1,PGBD2,LAPTM4A,RMND1,DYNC1I2,PAIP1,IQSEC1,NT5C2,PPFIBP1,CNOT8,SLC38A9,PPIB,HSPB1,ARRDC3,FLYWCH2,SNRPA,LCA5,PYM1,MRPS7,SAP18,RER1,RNF5,EMC1,NEK7,CD59,SLC16A10,TANK,PIH1D1,FDFT1,TMEM184B,FAM8A1,CTBP1,TMEM115,GTF2F1,SF3B4,IREB2,SNRNP40,TIMM21,LYZL6,CAVIN2,ATP5F1B,PCCB,COPS7A,POLR1B,THOC6,OSGEP,FTSJ3,COMMD9,TRAFD1,ERO1A,STX18,SLC25A11,ATP5PF,PALM2AKAP2,CAPZA1,FKBP8,SRPRB,TMEM33,CDC40,TMEM205,WBP11,RPAP2,MTCH2,UBL4A,SNAP29,TMEM165,TFRC,TFCP2,COMT,GTF2B,EEF1B2,STT3A,RBM42,TMPO,DKC1,NKAP,FCHO2,MIOS,RPS16,DNAJC1,ARL6IP5,MZT2B,ORMDL3,COPS5,HP,PGAM1,KARS1,USP15,RPS2,CDK12,LCP1,CWF19L1,EXOSC4,MARS1,RBM22,TRAM1,SLC35F6,STAT6,ACACA,HECTD1,GSTP1,USE1,H2BC11,GTF2H2,PSMC5,MOB4,GCFC2,LIG3,ZBTB33,RPS3,BCCIP,CEP41,PPAT,GABPA,BUB3,EXOC5,RPS17,CEP85,MORF4L1,C9orf72,CALU,CCDC174,ZFAND6,DNAJC10,PCNA,HECTD3,PRPSAP1,BCKDK,SYPL1,HNRNPA2B1,HSPD1,SACM1L,FLOT1,TMED7,SEMA4C,DHX16,ERLIN2,PPP2R1A,DLG3,MACO1,CSNK1E,SNRPE,AZIN2,GDI2,KRT8,RPLP2,TYMS,IFIT2,RPL8,DHX15,HSBP1,PRPF18,SLMAP,SRSF10,PPIA,ZNF207,IFIH1,PCNX1,ATG9A,PDAP1,DICER1,MED4,PPM1B,SYT4,PSMA3,ATP6V1G1,FBXO30,STX7,PAFAH1B2,HSCB,CA12,TOR1AIP2,GJC1,ACTL6A,MFAP1,LARP4B,ARMCX3,USP39,PSMB7,ZMAT2,GPR89A,SEC61B,SNRPD2,SLC23A2,ERH,CLIC4,NDUFAF4,PRRC2A,USP5,MAT2B,TAB1,ACTB,SPCS1,MED17,PRDX2,PRPF31,PIK3R3,VMP1,CNIH4,PFDN2,HSP90AA1,RPL23A,GNG5,CACUL1,SFXN1,TMED1,NKRF,TCOF1,PPP1R12A,RAB1A,RIGI,FASTKD5,EGR1,VTA1,FRMD8,VRK1,FARSA,NSMCE3,PGM1,TCAF2,GBE1,NDUFA2,TOR3A,DHRS7B,SERPINA1,TMEM156,TBC1D19,ACTR2,NDUFS3,LLPH,DAP,TES,MYBL2,DECR2,TFE3,PTPN1,RPL12,NCBP2,SEMA3C,THOC1,COG1,RPL35A,HM13,MOV10,OSBPL8,CNN3,SMG9,PRICKLE2,EIF5A2,RTN4,TCEA1,SPCS2,HMCES,KIN,TMUB1,CHMP2B,SLC7A1,CCNA2,RABL3,SYNGR2,CARHSP1,RARS1,CHMP1A,METTL14,GOLGA5,PICALM,DCTN4,RPS12,SFXN2,ALB,MSN,TRIM27,TUBA1B,METAP2,SCML2,COPE,PNP,HMOX2,CTNNBIP1,RACGAP1,DNAJC8,RPL26,CIAO1,ZNF687,DHPS,STK38L,HSPA14,ANKIB1,CDC73,SH3BP5L,ARFGAP3,SDF2L1,BCL9,CDK5,PRDM4,LSM14A,RAB18,TFG,CBLL1,RPS4X,PFDN1,VAMP8,RUVBL1,RPS7,NUP37,SPG21,NCSTN,H1-3,TMEM59,LIMD2,TMEM39A,PTRH2,PLS3,FAHD1,WDR82,PRCC,CCT7,HSP90AB1,TRMT61A,SNRPD3,SNRPA1,SUMO2,COMMD6,HNRNPL,ECHDC1,DBR1,RAB1B,DDRGK1,CTNNB1,YWHAG,NDUFV2,ZCCHC10,PTDSS1,RAB5C,MAGOH,PEX3,DDX1,CBL,DRG2,DDX5,DR1,SPECC1L,JAKMIP1,PEBP1,CD40,DDX39B,CERS6,PACSIN3,PHB2,TRA2B,FXR2,GOSR1,NDUFS2,MRPL12,ZC3H14,TIMM10,LAP3,ZER1,AKR1A1,CAV2,PPT1,MAP2K1,SMU1,PRMT5,LRP12,RETREG3,RRAS2,CDC42EP3,ALG5,ACAP2,PSMB6,NDFIP1,TAX1BP1,STAT1,MATR3,SLC1A3,SNRPB,BTF3,PSMA4,SFN,HNRNPAB,RPS26,PSMD14,MRPS25,CKB,KIAA1191,ZNF451,PSME1,MAP1B,RPL17,MEPCE,HNRNPK,SNRNP48,RHBDD3,ZNF581,TMSB10,ESS2,COMMD8,ATP5PB,GNAI3,ZFP1,CBX3,RP9,NT5DC1,ADD1,DSTN,ALYREF,LMAN1,RPS27L,MIF,CPNE1,EDC3,COMMD5,TSPO,AKAP8L,MED29,DOLK,BCL10,MED27,DERL1,MEA1,DLAT,DPAGT1,PGK1,LSM12,NBN,PML,IRF3,TRIM3,RPL27,SEPTIN6,GRPEL1,GCNT3,RPS15,NME4,AIF1L,CDC42,CD2AP,SYS1,SSR1,SYNGR1,SRP54,SEC61A1,GNAO1,UQCRC2,PSPC1,CDC20,RPGRIP1L,CHMP5,EIF4H,GORASP2,ST13,DNAJC5,CFL1,KCNQ5,NDUFAF2,MLF1,SUGP1,TMEM41A,RAB2A,TRIM32,ALKBH5,RBM7,SORD,OAT,EXOSC1,ATP1B3,COX8A,RPS24,UBE3A,SLC39A7,JAK1,ARB2A,ATF3,NDUFA4,PCGF6,ANP32B,RFC3,ETFA,G3BP1,LASP1,MARCKSL1,AP2S1,RNF126,PLD3,CYB5B,EIF1AX,STIM1,RPLP1,XPO5,OCIAD2,PHB1,FAM3A,DNM2,OS9,RAB11B,MPP1,ATXN10,SPTAN1,CCAR2,NOP58,EMC6,STOML2,PSMD3,PRDX1,RSBN1L,RASSF8,TMEM164,AHSA1,LBX1,KDM2A,CCDC86,NUBP2,ATP5F1E,ATP5MK,MCRIP2,G3BP2,UNC45A,PSMC1,NRBF2,POLA2,NSFL1C,ATAD1,TIMM29,ETF1,TMUB2,MTX2,TMEM231,MYL6,FAM3C,NDUFA5,SARM1,ARPP19,RMDN3,AP2M1,SLC30A7,SYBU,EIF3K,CYB5R3,FAU,RPL19,MAD2L1,RPL7L1,SPINDOC,RBBP4,MCM3,RFC5,SAMHD1,CFAP20,VEZT,USP13,DSN1,PFDN6,FCER1G,HINT1,EMC2,HSD17B10,TMX3,GLUL,SLC25A10,SNRPG,EIF3E,GALNT2,MDC1,RNF20,CTNND1,APH1A,HSPE1,SERTAD1,SEM1,YTHDF2,CCDC47,SERPINB9,SRP72,RAD23B,CASK,OTX2,ILF2,GABPB1,SEC23A,CLN8,H2AZ1,DFFA,AIFM1,G6PD,CAV1,TOP1,EIF2B5,MAPRE2,ARF6,EI24,BMPR1B,DNAJC7,ESYT1,SLC2A1,SQSTM1,MAVS,MTDH,PNO1,NCDN,TMEM209,AATF,USP8,NUCKS1,EIF5B,CERS2,PPP1R2,HACD2,IFRD1,GHITM,HSP90B1,CDK1,P3H1,ACAT1,TMSB4X,FBLN5,SMAP2,SEC63,TECR,RPL13A,TXN,MAGOHB,NONO,USP14,TUFM,GMPS,ATP5F1A,CYRIA,RETSAT,NDUFB10,XPOT,CCDC22,TDP1,SEC11A,PDIA6,RUVBL2,RPAP3,PABPC1,RBM3,RINT1,HNRNPDL,POLDIP3,RPL28,HMGN4,VDAC1,ZNF609,MSX2,CSTF2T,SERPINA3,PPIL3,STBD1,TOP3B,MTA2,GLE1,CORO1C,CEP57L1,TNIK,GNB3,PTK7,LANCL1,UQCRH,LYAR,TCP1,FAM98A,AFTPH,EIF2S1,STK4,EEIG1,GSTM3,FKBP4,TRIM22,HSPA8,XRCC5,RFC4,SLU7,RNF41,GNB4,SSR3,STAU1,EYA3,HNRNPA0,TLCD1,NDUFAF3,ISCU,YIPF5,DHRS4,ZNF362,SLC19A2,NUP62,NCOA5,KLC2,SIGMAR1,UBAC2,MRPS18A,GTF2F2,ANAPC2,ZNHIT6,EFHD2,TACO1,ATP6AP2,PSMD6,KCNH8,TRIM29,PSMD4,TIMP1,TBCE,TMED5,TMEM38B,NSA2,ICA1,RBM27,GCC1,ABCE1,RPL3,RBM41,SLC16A1,ATP2B4,NOSIP,MNAT1,SLC6A8,KPNA2,ZMYM4,GDE1,ARHGAP12,UBIAD1,H2AX,HADH,ACTR1A,CDK4,IPO8,PSMC3,TAF2,RNF8,TAB2,SIX5,ARPC3,NFE2L2,DNAJC2,GPD2,RGP1,COX4I1,NDUFB4,SYNCRIP,AIP,SDHB,LCN15,SURF6,CDC5L,SLAIN2,LRRC14,ILVBL,VPS26C,DNAJB2,ZNF24,SELENOS,AGPAT1,RPL10A,TMOD2,SNRNP70,TUBG1,PSMG2,RAB9A,PRDX6,RNF113A,BANF1,ZNF322,HSPA5,ZC3H15,TOMM20,NTPCR,GTF3C4,SPTBN1,UBE2M,VIPAS39,SAMM50,VPS4B,SDCBP,SGTA,QSER1,EIF2S2,PSMA6,ZNF330,CREB1,ROCK1,PPP1R10,SC5D,ADRM1,GPX1,TRIM54,PYGM,RALA,SUB1,NAA50,MAT2A,ATP1A1,HFE,EIF3G,TMEM147,SRSF7,SCD5,BAG2,THNSL1,SLC25A5,NEK9,ZYX,GPAA1,NUDT5,SSRP1,PSMD12,ATP5F1D,RPL29,ACTN4,FAF2,JUN,DCAKD,RBM12,CKS1B,ANP32A,DPH5,RPS11,RIMOC1,PPID,NME1,BZW2,EXOSC3,RPN1,SKA3,ATP6V1A,PSMB4,SPRED2,NUP35,STK3,PSD2,AGK,INA,TPH2,HNRNPA1,NDC80,DYRK1B,PDIA3,HMGA1,RAB32,MPHOSPH6,COTL1,VCPIP1,RB1CC1,HNRNPD,HAX1,UCK1,ELP6,ZCCHC9,CDK5RAP3,SKIC8,C1D,CMAS,YTHDF1,SRM,RADX,PPP2R2C,NUDT3,PGRMC1,NOTCH2,ANXA7,ARCN1,KCTD12,VAPB,RPS9,SNRPD1,VPS72,PNMA1,UBE2V2,TUBB,REEP4,PDLIM3,MRPL23,RANBP6,ATF1,RPS29,MRPL16,RAB11A,PKP4,PMPCA,PYCR1,CDC123,ZNF250,PFDN4,RPS5,SCFD1,YWHAZ,MRFAP1,FAF1,PTGES3,H2AC6,SMN1,TTC4,HUWE1,ERLEC1,EXOSC8,CD2BP2,PPARA,CCT5,ABHD4,MLLT11,SOD2,MMACHC,CHID1,PSMB1,EIF4E2,WDCP,TIMM8B,MSMO1,CWC15,TOMM70,CDK9,DERL2,ATP5MG,SMDT1,KIAA1143,POR,NME2,PPIH,KLHL28,ANAPC16,DVL2,PRIM2,CXXC1,DAD1,MFSD3,TTR,PDHB,SIT1,YKT6,KDELR2,TIMMDC1,SEC22B,UBA52,WTAP,HAUS2,STAMBP,SH3GLB2,KRT7,UBAP1,MET,STOM,NUDT12,ENO1,EIF2AK2,CTNNA1,DEK,PDCD5,MGST3,TMOD3,BRAP,PPIG,DNAJC19,GGCX,AP2A1,EWSR1,TRIM21,MYO1B,RPL31,PRPS1,CCAR1,PSMA1,HNRNPF,EEF2,TUBA1A,NUDCD3,ETFB,DCUN1D5,HGS,RPS23,GNAQ,NDUFA12,PDHA1,TUBB4B,STX5,YBEY,FUBP3,RBM5,RAB35,PEG10,AASDHPPT,RPS10,NOB1,EXOC1,NGDN,QPCTL,TENM3,XPO1,PFDN5,RPL6,ASB1,DDX50,CNOT2,UBFD1,CRTAP,NCK1,SF3B1,RPS28,NANP,ABCC5,SERPINB6,EEF1G,UFL1,SEC62,PSMB3,MTMR6,TOMM22,EFHD1,CNDP2,TRMT112,CKS2,NUFIP2,EIF4B,ACAA2,MRPL13,DLST,SESTD1,VDAC2,RPL10,CBX5,POLR2B,STAT2,CPSF2,UFD1,BAG3,PSMD1,HNRNPC,LDHB,CDKL2,ZMPSTE24,SERPINH1,ATP5MC3,RPS6KA4,CCT2,DHX9,PIK3AP1,RDH11,LPCAT3,POLE4,CSE1L,NUP107,PSMA5,PDE12,AKAP12,H3C1,NDST1,YIPF4,FAM162A,TP53,RPSA,STRBP,ID4,CAPZA2,SURF4,DDX42,RAC2,G6PC3,SLC39A10,MGME1,ITGA6,MRPS9,MYL12A,ESD,SNAP25,TMED9,CAND1,ELOC,TPM3,GAPDH,LYPLAL1,API5,COX5A,FITM2,TAF9,H2AC4,RPL24,BAP1,TEX264,CLU,WDR3,AGO1,DDIT4L,CYC1,LEMD3,TFIP11,HIKESHI,HBB,MACROH2A1,NECTIN2,CDIPT,SF3B6,NOPCHAP1,IDE,IRF2BP1,NUDT4,SMARCA5,SLC25A1,IFI35,PSMB2,CDKN2AIP,NPC1L1,IGF2BP1,ENDOD1,GLOD4 |
| 1.985e-44 | -100.63 | KRAS (KRAS proto-oncogene, GTPase) | protein interactions | 3845 | 2876 | 1126 | 19454 | 5460 |
NOS1AP,NXT2,CENPL,TUBG1,PSMG2,RPL10A,SELENOS,TMA16,FNDC9,PLSCR3,CDC5L,SURF6,PRELID1,COX4I1,SDHB,SYNCRIP,RGP1,MCL1,ACADSB,ARPC3,BMPR2,TAF2,PSMC3,PREB,UBIAD1,ARHGAP12,KPNA2,IMP4,CCIN,SLC6A8,ATP2B4,NOSIP,EIF1AD,NAE1,THG1L,SLC16A1,RPL3,RAB27A,ABCE1,LSM6,STXBP6,EIF3G,PSMG3,SNX5,RRP7A,ATP1A1,MED22,RPF2,NAA50,MAT2A,NCAPG2,SLC6A6,SC5D,RALA,ROCK1,PSMA6,TSSK1B,STX10,EIF2S2,SAMM50,CD46,WRAP53,TRIM36,UTP15,UBE2M,SPTBN1,CFTR,CCNH,PLP2,LPAR1,HSPA5,TOMM20,ZC3H15,POLD2,BANF1,SNAPC1,TWNK,AGR2,ANKRD50,YWHAB,CENPW,TBC1D5,LSM5,TCP1,AFTPH,EIF2S1,POLR2L,TNIK,PTK7,CORO1C,S100A8,ADGRG1,SEC61G,GLE1,ARL4A,RPL28,PABPC1,SDHC,TMEM87A,RPAP3,RUVBL2,EFNB1,SPCS3,NSA2,ARMC7,TBCE,ISCA2,HMGCS1,RPL39,LDB1,PSMD6,PSMD4,ATP6AP2,ZNHIT6,ANAPC2,GTF2F2,UBAC2,MRPS18A,PAK2,RASL10A,EBLN2,NUP62,RPL27A,ISCU,RPP21,HNRNPA0,RPP14,ZBTB5,XRCC5,SLU7,RFC4,COX17,HSPA8,ESYT1,SLC2A1,TOPBP1,GMPPB,EI24,RELL1,RAB23,PET117,EIF2B5,POLR2I,ARF6,CAV1,G6PD,SSU72,KRIT1,GABPB1,ZDHHC8,DMAP1,TMEM94,MRPL51,CASK,ILF2,CCDC47,THAP1,GGCT,POP5,PPIF,SLC29A1,HSPE1,SEM1,LSM4,EIF3E,SNRPG,OLA1,CTNND1,RNF20,HCAR1,EHD4,HSD17B10,SEPTIN7,FXN,SHOC1,XPOT,SEC13,GMPS,TUFM,NONO,ATP5F1A,RPL13A,TXN,TECR,PELP1,ZMAT5,HSP90B1,TMX4,CDK1,PTP4A2,TTI2,TPT1,SNRPN,WDR83,ATG16L1,USP8,IL1RAP,EIF5B,AATF,NLGN1,TMEM209,SLC2A3,GPX4,SQSTM1,ITGA2,KDM2A,BCL2L1,DPY30,UBXN6,PSMD3,RPL7,SPTAN1,ATXN10,MPP1,NOP58,COPS7B,OCRL,TMEM248,RAB11B,PHB1,DNM2,RPLP1,XPO5,NGB,STIM1,CYB5B,PLD3,AP2S1,EIF1AX,SF3B5,ENPP4,PGGT1B,MARCKSL1,DCUN1D3,WDR37,MAK16,RFC3,PPWD1,RPS24,JAK1,PFDN6,TXNRD2,CUL3,RRN3,CFAP20,VEZT,KDSR,GALE,MCM3,RIOK2,RFC5,RPL7L1,RBBP4,MTM1,RPL19,ITM2A,MAD2L1,CPSF1,ARF1,INMT,FAU,RPL37A,SLC30A7,AP2M1,PCLAF,ABCB1,MYL6,MTX2,FAM234A,ALKBH3,RPE,ETF1,TIMM29,EHD1,NSFL1C,G3BP2,IGSF21,ZDHHC17,POLA2,PSMC1,UPF3B,NUBP2,TRAPPC2L,RPL24,SHC1,VASH1,TRMT5,PLEKHO1,ELOC,GAPDH,SNAP25,CAND1,STX6,RASGRP2,RPL32,MRPS9,ACSL4,SSBP1,ITGA6,RAC2,SLC39A10,EXOC3,DDX42,CDK8,RAD1,BIRC5,RPSA,CENPM,IMP3,CSE1L,AKAP12,NEDD8,PSMA5,NUP107,DHX9,DTL,PSMB2,CARS1,RGL2,SMARCA5,CNNM4,IRF2BP1,NOPCHAP1,UBA3,RSL24D1,NECTIN2,ALG2,CDIPT,MACROH2A1,CSNK2B,PHAX,LEMD3,CSNK1G3,CYC1,LUC7L3,TFIP11,IGFBP3,OIP5,WDR3,DNLZ,ITM2B,NLE1,LIN7C,BAP1,DDX46,DPH3,ZBED3,PSMG4,FCGR1A,SLC38A7,PFDN5,RPL6,DDX50,CNOT2,TENM3,EXOC1,YWHAH,XPO1,DNTTIP1,NOL4,NOB1,ISG20L2,CDK17,RPS10,FHIP1B,CSRNP1,STX5,LSM10,TAF10,RPS23,HGS,DHX38,SPC24,EEF2,COX4I2,HNRNPF,NAB1,USP30,PSMA1,SLC35A2,GNA11,RPL31,MYO1B,EWSR1,PIK3CG,FBXW11,CCT2,YAE1,SERPINH1,RCL1,ATP5MC3,HNRNPC,MYC,CPSF2,KANSL3,PSMD1,RPL10,NCKAP1,POLR2B,KTI12,CMTR1,MCPH1,RCE1,GPN2,TRMT112,CSNK1A1,EIF4B,PSMB3,TOMM22,ATP6V1C1,IL6ST,UFL1,ABCC5,HIGD2A,RPS28,SF3B1,POR,UQCR11,TRAPPC4,DAG1,CDK9,KRR1,TSR2,PSMB1,DLGAP4,POLR2G,CIBAR1,CCT5,FCF1,EXOSC8,TTC4,HUWE1,SMN1,PSEN1,TRAPPC1,IGF1R,SNAPC3,GMNN,TMOD3,VIRMA,GNAI2,PDCD5,UBE2L3,ENO1,CTNNA1,GAB1,POLR3H,SLC11A2,STOM,UBE2F,SLC12A2,COX6C,SHOC2,AGAP1,WTAP,MET,STAMBP,UBA52,SEC22B,PIP5K1A,NFYB,PDE8A,ABHD5,FBXW7,YKT6,COL3A1,MRPL17,LSM8,UTP23,MRPL20,VPS28,DAD1,NOG,PRIM2,SOD1,ZCCHC9,ELP6,WDR12,SLC25A26,HMGA1,PIK3R1,LIPT2,INA,NUF2,MRTO4,PSMB4,SPRED2,RPL9,SDHAF2,ATP6V1A,AZIN1,EXOSC3,RPN1,SART3,STX12,POLR2C,RPS11,ANP32A,DPH5,RBM12,HSDL2,FAF2,ATP5F1D,GUK1,AHCYL1,PSMD12,RPS27A,BAG2,MRPS11,SRSF7,PLCB1,ZCRB1,YWHAZ,SCFD1,SLC7A11,CCDC25,RPS5,PMPCA,RAB11A,PKP4,RPS29,MAP3K21,TUBB,LGALS3,ABHD12,VPS72,RPS9,POLR3B,SNRPD1,VPS18,SKA2,VAPB,KCTD12,SLC25A3,ARCN1,NOTCH2,PGRMC1,DUSP22,MED11,CDK12,RPS2,PGAM1,RBM17,KARS1,CCL5,COPS5,FCHO2,ARL6IP5,RPS16,DNAJC1,DKC1,TMPO,FUNDC2,CAMLG,STT3A,GTF2B,TRAPPC3,NUDT9,TMEM165,TFRC,GRAP2,GFM2,MTCH2,RAP1A,SRFBP1,SNAP29,RRM1,RPAP2,MECR,URM1,GLRX5,SRPRB,PDRG1,PALM2AKAP2,RAB13,STX18,RAP2C,CCDC174,ANAPC4,RPS17,GABPA,PPAT,BUB3,MRPS21,SRPK2,SRC,ATL1,RPS3,FKBPL,GTF2H2,MOB4,PSMC5,USE1,EIF2B3,STX17,RPA2,QRSL1,RPRD1B,ACACA,PPP1R8,MRPL10,SNRNP27,MRPL40,RBM22,MARS1,ABCC2,EIF4E,NMBR,LCP1,EXOSC4,CWF19L1,HSPB1,TNFSF13,DRG1,PPP1R11,CIAO3,MDFI,UTP6,PPFIBP1,DYNC1I2,PGS1,TMEM97,VAMP7,SRSF1,RFX4,SMNDC1,ADCY3,RPL18,AAMP,RANBP1,UBL5,MAX,KRAS,CYP11B1,CD83,CCT8,CTTNBP2,RTCB,RABGGTB,FBXO11,FTSJ3,TAS2R5,COX16,LAMTOR1,THOC6,POLR1B,SLC38A1,OSGEP,EPS8,MLF2,PLXNC1,SNRNP40,ATP5F1B,IREB2,ZNF189,TRIM44,GTF2F1,SF3B4,FAM83B,ADSS2,TMEM115,PALS2,GOSR2,PAFAH1B1,CNPY3,RER1,EMC1,SAP18,DPH6,HIRA,MPHOSPH10,TIAM1,PSMD7,MED21,CGB8,GALNT17,SLITRK2,ORC5,TMEM199,CALR,MFN1,EIF2B2,ALCAM,ATP5PD,NAA11,RCHY1,EHBP1,SRP14,SRPRA,PWP2,LRRC4B,CDCA3,MRPL49,PDLIM4,PPP4C,RPL15,BCS1L,EEF1A1,ALG11,LBR,THRAP3,CTNNBL1,CAMK2G,PAK1IP1,ARF4,SFT2D2,RPS13,VWF,DLG1,STX8,SPSB1,NSDHL,SNAP23,SHISA2,TTPAL,HAPSTR1,CHORDC1,TADA1,EPHA2,NAPA,FLRT3,PNPLA4,CDC16,PPP1CC,HYCC2,DEPDC1B,SNX3,YES1,F11R,RAB14,RILPL2,RPL22,SH3BP4,VKORC1L1,EIF4A3,VAMP3,HYCC1,CFAP298,RPS20,UBE2I,DTYMK,LSM2,MRPS34,JUP,PDCL,CDAN1,RPLP0,CCND1,MYLIP,CPSF4,PSMC4,RPS14,CNP,ELP3,SIPA1L1,RPL4,SMC4,NHP2,PRPF4,ARPC2,SYVN1,TRAF6,UBE2D1,DDX23,RPL23,LRRC57,C2CD2L,PRPF19,EIF3D,SNX2,BUD31,POLR3F,RGCC,PPP2CB,WDR6,CYB5A,COPS2,IGBP1,GJA1,NEO1,VAMP2,GNB1L,MFAP3L,GTF2E2,TULP3,GFPT1,ASPM,CYB5R1,EMC8,RFC2,MCM6,KLHL25,PPAN,ARGLU1,MORC2,AKT2,PLSCR1,ATP6V0B,LMNB1,WDR20,NOP16,CUL2,MCM4,RNF40,RHEB,TOMM40,RPL35,CHP1,TNPO3,CHCHD3,GGPS1,PELO,RAN,CLDN3,CDC7,LRRC1,ATP5PO,RTF2,WDR77,RAB6A,PPP1CB,TIMM13,SLC15A1,MCMBP,SKP1,TSPAN15,THOC3,PMAIP1,CLDN1,SLITRK5,DOLK,ATP6V1D,MAGEB1,NOL12,DHRS7,ENY2,RPAIN,VTI1B,LMAN1,SLC38A2,UBE2N,ALYREF,OR2H2,METAP1,FLRT2,ADD1,AGER,PIK3CA,GNAI3,MVD,GNPNAT1,ESS2,ZNF581,RPIA,HNRNPK,RPL17,MEPCE,EDA2R,GEMIN8,CHCHD4,CISD1,UBE2H,EXOSC1,CCNB1,NDUFAF2,ST13,GORASP2,ARHGAP21,CFL1,CDC20,UQCRC2,PTPMT1,SEC61A1,TRAF7,SRP54,SYS1,SSR1,SEPHS2,GTF2H4,CDC42,FTSJ1,ADAMTS10,RPS15,GRPEL1,UGP2,PIP4P1,WDR55,NBN,TRIM3,PML,SEPTIN6,RPL27,DPAGT1,SMG5,GFM1,ELOF1,PGK1,MAGOH,DDX1,CDC23,CTNNB1,DDRGK1,OLR1,YWHAG,OSBP,SUMO2,SNRPA1,SNRPD3,COCH,DBR1,HNRNPL,HSP90AB1,CHMP2A,CCT7,PCDH9,C2CD4C,WDR82,PTRH2,MOB3C,SLC4A8,SPG21,NUP37,RPS7,RUVBL1,SLC20A2,ROCK2,PSMA2,EPHA4,VAMP8,PFDN1,RPS4X,COX7B,LTO1,ABCF1,OAS1,MRPS25,PSMD14,SLCO3A1,PELI3,RPS26,PHF7,SFN,PSMA4,COX6B1,RALGAPA2,SLC1A3,MATR3,TAMM41,RNF141,PSMB6,MTG1,INTS10,PRMT5,RRAS2,SMU1,MAP2K1,MED31,USP6NL,TIMM10,MRPL12,PHB2,SLC31A1,GOSR1,SRSF2,TMEM177,GINS3,DR1,DDX5,ECD,PROM1,ANKRD49,GTF2A2,OSBPL8,CLP1,ERCC3,HM13,THOC1,SEMA3C,RPL35A,NHEJ1,RPL12,PTPN1,HRAS,MYBL2,ACTR2,GINS4,PDE6D,DTD1,TCAF2,CMPK1,HINFP,UBE2V1,FNTB,NSMCE3,FARSA,VRK1,NOC4L,ANAPC11,ADD2,VPS16,NKRF,RAB1A,PPP1R12A,TGIF2,GNG5,RPL23A,CCNY,LRP6,CDC73,DHPS,CIAO1,HSPA14,RACGAP1,HMOX2,DNAJC8,RPL26,RPP25L,COPE,FERMT2,POP7,METAP2,TUBA1B,CTU1,MSN,ODR4,RPS12,COA5,PICALM,METTL14,DCTN4,CTDSP1,RARS1,ARHGAP1,ADIPOR1,LIAS,SF3A1,RABL3,TXNL4A,CDK7,CCNA2,MED30,UQCRC1,PIK3R2,NF2,SLC7A1,CDC42EP4,BRIX1,DCTN6,RPA3,KICS2,SPCS2,TCEA1,KIN,SLC20A1,DICER1,MED4,INO80E,VPS26A,ZNF207,HYPK,DHX15,TMEM237,WDR44,DIRAS3,PSMB5,RPL8,RPLP2,TYMS,SLCO2B1,SNRPE,DOHH,ITGB5,POLR2D,DLG3,RAF1,BUD23,NAA15,MACO1,IFNGR1,SEMA4C,UFM1,DHX16,COPS4,FLOT1,SACM1L,GTF3C3,HNRNPA2B1,HSPD1,PCNA,SENP8,FAM219A,VMP1,HSP90AA1,PFDN2,MTG2,NIBAN2,PRPF31,LAMTOR3,RPF1,ACTB,SPCS1,STARD7,LRRC8A,ERH,FAM91A1,SLC23A2,POLR2F,SEC61B,SNRPD2,OR4K1,PSMB7,USP39,KIAA0040,MFAP1,TOR1AIP2,CA12,GJC1,SUPT4H1,NOP53,RP2,HSCB,ATP6V1G1,STX7,EXD2,CFDP1,PSMA3 |
| 2.212e-44 | -100.52 | UFL1 (UFM1 specific ligase 1) | protein interactions | 23376 | 1015 | 489 | 19454 | 5460 |
BUB3,SRPK2,ROCK1,GCFC2,PSMA6,RPS3,EIF2S2,PSMC5,MRPS28,EIF3G,ELAVL2,ATP1A1,SUB1,RPF2,MAT2A,RPS17,MRPL41,HSPA5,ZC3H15,TOMM20,BANF1,PRDX6,RAB9A,CWF19L1,HNRNPH2,EXOSC4,ZNF326,SAMM50,IDH2,RPA2,SDCBP,ACACA,GSTP1,SPTBN1,NTPCR,GTF3C4,MRPL10,RPS16,DNAJC1,CDC5L,RBM42,TMPO,EEF1B2,SYNCRIP,SNRNP70,TMEM11,RPL10A,RPS2,RBFOX3,RBM17,CMSS1,KARS1,TMA16,IMP4,KPNA2,TMEM33,CAPZA1,FKBP8,SLC25A11,ABCE1,SLC16A1,RPL3,DNAJC2,IK,PSMC3,CDK4,MTCH2,ACTR1A,PSMD6,ATP5F1B,PSMD4,APLNR,SF3B4,H1-10,FTSJ3,OST4,CASP4,STAU1,HNRNPA0,MRPS7,RANBP10,XRCC5,SNRPA,RFC4,EP300,HSPA8,RPL27A,LYAR,TCP1,FAM98A,EIF2S1,SRSF1,MAGED2,CORO1C,DRG1,RIOX2,GSTM3,KRAS,HNRNPDL,POLDIP3,RPL28,PABPC1,CCT8,RTCB,PDIA6,RUVBL2,RPL18,MTA2,RANBP1,RPL13A,MAGOHB,TXN,LDHA,ZNF622,RPL22,SEC63,TECR,EIF4A3,STUB1,PELP1,OPTN,ACAT1,RPS20,GANAB,PRKRA,RTRAF,SAYSD1,IVNS1ABP,IRAK1BP1,NONO,TUFM,PPP1CC,GMPS,ATP5F1A,HMGB1,PFKFB2,RPL4,NPM3,EIF5B,GTF2I,CSTB,ARPC2,MTDH,SYVN1,HSP90B1,MRPS34,TIMM23,CDK1,RPLP0,MYL12B,EEF1E1,PSMC4,RPS14,CNP,PRNP,TOP1,SLC25A12,AKAP17A,SRP14,HACD3,AIFM1,PWP2,HSD17B11,PSMD7,DNAJC7,GLO1,THRAP3,CD80,PAK1IP1,EIF3E,PRDX4,RPS13,ARF4,ZNF787,SLC25A10,HSD17B10,HAPSTR1,ZC3H11A,ILF2,MRPL11,CCDC47,COMTD1,TBK1,RPL15,DDX39A,LBR,RPL7L1,RPL35,SPINDOC,RBBP4,DYNLL1,RPL19,CHCHD3,RAN,EIF3K,CPSF1,RMDN3,RPL37A,AP2M1,MYO6,LMNB1,FAS,GPR17,CFAP20,MCM3,GGH,MCM4,TOMM40,RFC5,G3BP2,ATP5MK,UPF3B,THOC3,ATP5PO,MYL6,MTX2,WDR77,PRDX3,SPTAN1,RPL7,NOP58,WIF1,CACYBP,PHB1,WDR6,THOC2,HP1BP3,RPLP1,GJA1,PSMD10,DDX23,RPL23,AHSA1,STOML2,PSMD3,PRPF19,PRDX1,EIF3D,TRA2A,KCTD17,G3BP1,RBBP7,RFC3,MRPS17,TMT1A,NDUFA4,RPS24,JAK1,VPS33A,STIM1,GTPBP1,SF3B5,TXNDC12,RPP25,UQCRC2,PSPC1,SF3B6,MRPS16,UBE2H,IGF2BP1,RPL7A,SLC25A1,PSMB2,CFL1,STK38,RPS15,IRF3,MAIP1,DDX46,RPL27,DERL1,SSR1,LUC7L3,CYC1,TFB1M,TFIP11,CDC42,MIF,PLG,CAND1,LMAN1,ALYREF,RPL32,MRPS9,SSBP1,RAC2,RPL24,H2AC4,SMCHD1,LSM3,KPNA1,ENY2,TPM3,GAPDH,HNRNPK,RAB3B,CSE1L,RPL17,MEPCE,MAP1B,DHX9,CBX3,TP53,RPSA,APOO,NDFIP1,MATR3,ACAP2,RPL10,ESR2,POLR2B,LMBR1L,VDAC2,SMU1,PRMT5,PSMD14,MRPS25,CIRBP,CCT2,CKB,RCL1,HNRNPC,PSMA4,LDHB,HNRNPAB,SNRPB,CPSF2,PSMD1,ATG101,PHB2,EEF1G,TRA2B,FXR2,SRSF2,UFL1,CHRNA7,DDX5,OR1M1,SF3B1,TRMT112,EIF4B,LAP3,TOMM22,MRPL12,SEC62,SNRPD3,SNRPA1,HNRNPL,RPS10,CCT7,HSP90AB1,SELENOM,MT1M,DDX1,PTDSS1,RPL6,DDX50,DDRGK1,QPCTL,XPO1,RUVBL1,HNRNPF,PRPS1,RPS4X,ABCF1,LSM14A,RPL31,TRIM21,EWSR1,MYO1B,PDHA1,PTRH2,PLS3,TUBB4B,MOB3C,RPS23,CCR1,PTS,TRMT1L,RPS7,EEF2,TUBA1A,MGST3,DEK,UQCRQ,TUBA1B,ENO1,EIF2AK2,RPS12,ALB,ODR4,CDC73,AP2A1,STK38L,RPL26,FBXW7,BRIX1,RPA3,METTL14,STOM,HNRNPH3,RARS1,SF3A1,TSC22D3,CGAS,RPL35A,MRPS23,KRR1,PTPN1,RPL12,PSMB1,NME2,OSBPL8,GRSF1,MOV10,NOC4L,FARSA,PTGES3,NKRF,RPL23A,CCT5,HINFP,EXOSC8,ACTB,TAB1,TUBB,PRDX2,ERH,S100A6,SEC61B,RPS9,SNRPD1,SNRPD2,YWHAZ,RPS5,PFDN2,HSP90AA1,RPS29,PRPF31,RADX,HSCB,CMAS,PXMP2,PSMA3,FOXS1,SLC25A3,MFAP1,PGRMC1,AGK,DHX15,SRSF10,PPIA,PSMB4,MRTO4,RPL9,RPL8,RPLP2,PPM1B,CDK5RAP3,MPHOSPH6,RB1CC1,MRPS26,HAX1,HNRNPD,HNRNPA1,TNF,UFM1,SSRP1,RPS27A,GTF3C3,PSMD12,HNRNPA2B1,SLC25A5,SCYL2,HSPD1,SRSF7,BAG2,PCNA,PRPSAP1,EXOSC3,GDI2,RPN1,SNRPE,RPS11,HSDL2,ERLIN2,PPP2R1A,RPL29,FAF2 |
| 3.697e-43 | -97.70 | RPA2 (replication protein A2) | protein interactions | 6118 | 2885 | 1124 | 19454 | 5460 |
COX6B1,CREBBP,SFN,HNRNPAB,PSMA4,BTF3,SNRPB,STX16,CKB,ADK,PSMD14,S100A11,RPS26,CRMP1,MDH1,MIDEAS,PRMT5,RETREG3,ZMYM2,SMU1,MATR3,TAGLN2,TAMM41,STAT1,ALG5,ZC3H14,MAP2K1,PPT1,MED31,AKR1A1,DDX39B,PEBP1,DDX5,NDUFS2,FXR2,PHB2,CERS6,RAB5C,PTDSS1,CTNNB1,DDRGK1,BTF3L4,GSTO1,DEGS1,AK2,DRG2,CBL,DDX1,PEX3,CDC23,ARMC8,SIN3A,PRCC,ANXA4,SWAP70,HDHD5,WDR82,RAB1B,HNRNPL,DBR1,OSBP,SNRPD3,TRMT61A,HSP90AB1,CCT7,H1-3,NCSTN,FOXJ3,RPS7,PTRH2,ABCF1,CDK5,PSMA2,COA1,RUVBL1,ROCK2,XPNPEP1,VAMP8,RPS4X,CBLL1,TFG,RAB18,RAB2A,SUGP1,CCNB1,RPL7A,CFL1,ST13,CISD1,ATP1B3,BICD2,OAT,SORD,PSPC1,UQCRC2,SEC61A1,PITPNB,SRP54,INTS12,EIF4H,CHMP5,CDC20,CD2AP,CDC42,SSR1,RPL27,MAIP1,NBN,PGK1,DLAT,GFM1,DERL1,STK38,UGP2,EDC3,RPAIN,MED27,SMCHD1,NUS1,UBE2N,ALYREF,RAP1B,ADD1,MTAP,CDK6,NT5DC1,CPNE1,MIF,LMAN1,SLC38A2,MVD,ATP5PB,ESS2,GNPNAT1,CBX3,NUPR1,GNAI3,MAP1B,ZNF451,PSME1,BCAP29,HNRNPK,MEPCE,RPL17,ACO2,NIBAN2,TMED4,SMARCE1,PRPF31,PFDN2,HSP90AA1,RMI1,FAM91A1,SNRPD2,SEC61B,PRDX2,IP6K1,RPF1,MED17,ACTB,MAT2B,PRRC2A,NDUFAF4,ERH,CLIC4,ACTL6A,USP39,ISOC1,ELOVL1,MFAP1,CFDP1,PSMA3,PAFAH1B2,PYGB,STX7,FBXO30,VPS26A,ZNF207,MED4,DICER1,PDAP1,RPL8,PSMB5,TYMS,HYPK,SRSF10,PPIA,WDR44,DHX15,BUD23,NAA15,CSNK1E,PPP2R1A,ERLIN2,RAB6B,GDI2,SNRPE,HSPD1,SYPL1,HNRNPA2B1,MKLN1,PCNA,DHX16,S100A10,TMED7,GTF3C3,COPS4,FLOT1,RAD21,SACM1L,HSPA14,STK38L,ZNF687,RPL26,DNAJC8,RACGAP1,ARFGAP3,CDC73,MAPRE1,GXYLT1,GTF2A1,CMBL,GNPDA1,MSN,RPS12,SFXN2,PNP,FERMT2,SCML2,CEP97,SF3A1,SYNGR2,ARHGAP1,CCNA2,CDK7,PICALM,CZIB,HNRNPH3,RARS1,RPA3,KIN,HMCES,SPCS2,TCEA1,RTN4,NF2,SLC7A1,BRIX1,MOV10,HM13,ATP1B1,CNN3,SMG9,OSBPL8,PTPN1,RPL12,EFNA3,ACTA2,RB1,TES,COG1,RPL35A,THOC1,MRPL24,TMEM126A,FBP1,GBE1,UBE2V1,PGM1,GINS4,NDUFS3,ACTR2,DHRS7B,RAB1A,PPP1R12A,NKRF,TCOF1,SFXN1,RPL23A,LIPA,VRK1,FARSA,NOC4L,VTA1,FASTKD5,ADD2,VPS16,ABHD10,COPS7A,RBBP8,LAMTOR1,FTSJ3,H1-10,OSGEP,THOC6,POLR1B,GTF2F1,SNRNP40,TIMM21,PPP5C,GOSR2,SHMT1,PLAA,ADSS2,FDFT1,SNRPA,HIRA,RAB5A,EMC1,RER1,SELENOO,MRPS7,PPIB,UTP6,NT5C2,HSPB1,DRG1,MPDU1,MAGED2,TRIR,DYNC1I2,VAMP7,TMEM97,MACROD1,MAX,ARFGEF1,SUPT5H,RANBP1,TRAF2,SOX2,NUDT19,RAB4A,ZRANB2,CRKL,RPL18,CCT8,TOP2B,PICK1,RABGGTB,RTCB,KRAS,SATB1,VPS39,MORF4L1,RPS17,EXOC5,RAP2C,DNAJC10,CALU,ACOX1,RPS3,GCFC2,LIG3,MOB4,PSMC5,BUB3,PPAT,BCCIP,SRC,CAPN1,SETD3,RPA2,CSNK1A1L,RPRD1B,EIF2B3,GSTP1,ACACA,TMX2,UGDH,CWF19L1,LCP1,NAPG,RBM22,MARS1,KARS1,PGAM1,RBM17,COPS5,CDK12,RPS2,STT3A,COQ8A,EEF1B2,GTF2B,COMT,ARMC1,TRAPPC3,ARL6IP5,RPS16,DKC1,TMPO,SNAP29,RRM1,MTCH2,WBP11,ZMYM3,TMEM205,TFRC,TFCP2,TMEM165,TBC1D4,SESN2,SLC25A11,RAB13,ERO1A,CDC40,KDM4B,TMEM33,SRPRB,FKBP8,CAPZA1,CUL2,TOMM40,RHEB,MCM4,GGH,BLVRA,LMNB1,EXOC8,RIT1,PIGK,RAN,UBE2S,MB21D2,TSN,DYNLL1,UMPS,RPL35,GNB1,TNPO3,SNRPB2,LNX2,IDH3B,PPP1CB,PRDX3,RAB6A,APOBEC3C,PPARG,MED23,ADNP,RTKN,NUP50,TTC1,HADHA,LZTFL1,MCMBP,NT5C3A,COIL,SKP1,PRPF19,EIF3D,WDR11,DDX23,TST,RPL23,PPP3CA,THOC2,WDR6,MYEF2,COPS2,SNX2,ERLIN1,CACYBP,CETN2,TXNRD1,NUP153,GFPT1,CYB5R1,VPS33A,RBPJ,GTPBP1,MORC2,AKT2,PPAN,ARGLU1,ZC3H7A,RBBP7,ZBTB14,MCM6,HS2ST1,RFC2,CDC16,AAMDC,PPP1CC,CHORDC1,EPHA2,CA2,NAPA,VAMP3,QNG1,STUB1,EIF4A3,GANAB,CAB39,RPS20,ZNF622,LDHA,RAB14,SLC25A4,VKORC1L1,RPL22,RPS14,RBFOX2,PSMC4,EEF1E1,ELP3,CNP,JUP,LMNA,MRPS34,RPLP0,EPHX1,OXSR1,ZNF574,MACROH2A2,ARPC2,GTF2I,HMGB1,RPL4,SMC4,POLDIP2,ORC5,TLE1,EMC4,GLO1,MPG,LRRC40,CD9,PSMD7,EXOC2,SRPRA,HACD3,SRP14,PWP2,EIF2B2,PLGRKT,TBK1,EEF1A1,LBR,DDX39A,NECAP2,RPL15,UBR7,BCS1L,PPP4C,APEH,NSDHL,SNAP23,PC,PAK1IP1,CTNNBL1,CAMK2G,THRAP3,WASL,ARF4,RPS13,PRDX4,MSH6,HNRNPC,LDHB,CCT2,H2AZ2,SERPINH1,RCL1,ZMPSTE24,VDAC2,DLST,CMTR1,SSH3,POLR2B,LRIF1,CBX5,APEX1,NCKAP1,TOMM22,ATP6V1C1,MTMR6,PSMB3,QTRT2,SEC62,EIF4B,NUFIP2,CNDP2,CSNK1A1,NANP,JAGN1,SF3B1,UFL1,EEF1G,SERPINB6,LYPLA2,BAZ1B,CNOT2,DDX50,RPL6,YWHAH,XPO1,DNTTIP1,NGDN,EXOC1,ARHGAP5,UBFD1,DDT,RAB35,GYS1,FUBP3,STX5,RPS10,AASDHPPT,TRMT1L,ETFB,DHX38,GCLC,EEF2,TUBB4B,RPS23,DCUN1D5,RPL31,GNA11,MYO1B,EWSR1,DCP2,HNRNPF,PSMA1,DCTPP1,CCAR1,UTP25,PRPS1,RAB8B,CARS1,SLC25A1,PSMB2,AKT1,SMARCA5,PDCD4,IGF2BP1,CDKN2AIP,CDIPT,SF3B6,ALG2,PHAX,MACROH2A1,PPP2R5E,RNASEH1,IDE,HIKESHI,TFIP11,LEMD3,LUC7L3,CYC1,DDX46,BAP1,NLE1,ARFIP1,WDR3,MTMR12,ANKMY2,PPIL4,API5,GAPDH,RPL24,H2AC4,TAF9,KPNA1,MAP4,MRPS9,ACSL4,SSBP1,MGME1,RPL32,XXYLT1,CAND1,TMED9,KCTD3,ESD,STRBP,TP53,RPSA,FAM162A,APOO,DDX42,SURF4,CAPZA2,SH3GLB1,SLC25A24,RAD1,DHX9,PDE12,H3C1,NUP107,CSE1L,LPCAT3,CTSC,RDH11,ZNF250,CDC123,PMPCA,TM9SF4,RAB11A,JPT1,MRPL16,ELMOD2,ARHGAP19,BRCA1,YWHAZ,SCFD1,RPS5,ILK,ARMT1,CNOT6,RSRC1,POLR3B,SNRPD1,RPS9,EIF4A2,TUBB,REEP4,RRAGA,PGRMC1,STXBP1,VAPB,KCTD12,SLC25A3,ARCN1,ANXA7,TBC1D24,TXNL1,EMG1,CYFIP2,SRM,YTHDF1,CMAS,RAB32,PDIA3,MAP1S,HNRNPA1,WDR12,UCK1,HNRNPD,VCPIP1,RB1CC1,COTL1,RPL9,PSMB4,MRTO4,ATP6V1A,SNX17,RBM12,ANP32A,ARFGAP1,HSDL2,DCAKD,FAF2,JUN,RPL29,ACTN4,RPN1,SKA3,BZW2,EXOSC3,RIMOC1,PRKAG1,STX12,RPS11,JPT2,SART3,SCYL2,NUDT5,GPAA1,ZYX,NEK9,SLC25A5,BAG2,MRPS11,PSMD12,UBE2A,SSRP1,AHCYL1,SAR1B,BRAP,AP2A1,DNAJC19,EIF2AK2,CTNNA1,ENO1,CTTN,MGST3,TMOD3,CPT2,UQCRQ,GNAI2,PDCD5,DEK,SEC22B,TIMMDC1,UBLCP1,COX6C,STOM,UBAP1,PRIM2,PPM1G,HELLS,DVL2,NDUFC2,YKT6,PDHB,DAD1,PIAS1,ATP5MG,FOXP1,WDCP,EIF4E2,KRR1,CHID1,PSMB1,DCUN1D1,TOMM70,CDK9,CCT5,CD2BP2,FCF1,EXOSC8,HUWE1,FN3KRP,PAPOLA,TBCE,HMGCS1,LDB1,SPCS3,RBM27,CHTOP,NSA2,EFHD2,PHF21A,GTF2F2,PSMD4,PSMD6,RPL27A,PAK2,UBAC2,SIGMAR1,KLC2,SLU7,RFC4,XRCC5,HSPA8,AKAP1,STK26,HNRNPA0,STAU1,SSR3,GSTM3,TBC1D5,FKBP4,YWHAB,SERPINC1,TNIK,CORO1C,EED,EIF2S1,FAM98A,TCP1,LYAR,LANCL1,TOP3B,CCDC134,CSTF2T,KIF2A,SEC61G,MTA2,NDUFB5,RINT1,PABPC1,RPAP3,RUVBL2,PDIA6,VDAC1,RPL28,HNRNPDL,POLDIP3,MAT2A,NAA50,RPF2,SUB1,FOXA3,GSTK1,PTPN11,NCAPG2,EIF3G,SERTAD3,SERPINB1,ATP1A1,SNX5,EIF2S2,QSER1,STX10,RALA,GMDS,RPL10L,CSTF3,PPP1R10,SPTBN1,CCNH,NTPCR,TRMT13,IDH2,SAMM50,VIPAS39,UTP15,UBE2M,PRKCA,APMAP,THUMPD1,PRDX6,ACP5,KDM1A,TOMM20,HSPA5,CMSS1,CSNK2A1,PSMG2,TUBG1,RPL10A,AGPAT1,SYNCRIP,COX4I1,PREP,AKR1B1,VPS26C,SELENOI,ILVBL,CDC5L,SURF6,PREB,IPO8,TNRC6C,CDK4,ACTR1A,HADH,H2AX,ZMYM4,GPD2,CHAMP1,IK,ARPC3,RBM34,TAB2,NAE1,SLC16A1,RPL3,ABCE1,IDH1,THG1L,KPNA2,IMP4,MNAT1,NDUFB6,USP13,KDSR,HNF1B,VEZT,CUL3,CFAP20,RFC5,MCM3,MYO6,ARF1,CPSF1,FAU,CYB5R3,EIF3K,PARP2,SLC30A7,AP2M1,RPL37A,SARM1,RBBP4,RPL7L1,MAD2L1,RPL19,MTX2,NRDE2,ETF1,TIMM29,FAM3C,ATP5MK,NPTN,ATAD1,NSFL1C,POLA2,PSMC1,UNC45A,PRDX1,PSMD3,MARCHF5,STOML2,MRPS35,RHOG,AHSA1,PDCD10,SLC25A21,DNM2,PHB1,OCIAD2,TSG101,XPO5,HP1BP3,RPLP1,NOP58,OCRL,COPS7B,SPTAN1,CCAR2,SNX1,RPL7,MPP1,ATXN10,NTMT1,RAB11B,LRWD1,FEN1,STIM1,NGB,PLD3,OTULIN,CYB5B,AP2S1,TMT1A,NDUFA4,RPS24,UBE3A,LASP1,G3BP1,GNL1,PPWD1,AP1M1,RFC3,ANP32B,CTSD,CSK,SEC13,ATP5F1A,TUFM,USP14,GMPS,NONO,STK24,TADA3,CCDC22,XPOT,PELP1,CYRIB,RTRAF,GSK3A,TRIM24,ACAT1,TXN,RPL13A,TECR,ZNF507,SEC63,SAP30BP,ATG16L1,TPT1,SPR,FUT8,EDF1,EIF3J,TIMM23,CDK1,TOX4,HSP90B1,GHITM,CDR2,IFRD1,PITPNA,NCDN,PNO1,MTDH,MAVS,SQSTM1,EIF5B,NUCKS1,USP8,CRYZ,GABARAP,TMEM209,ISYNA1,GMPPB,TTL,SLC2A1,ESYT1,DNAJC7,TOPBP1,AIFM1,SEC23A,ARF6,MAPRE2,TOP1,EIF2B5,SLC25A12,CAV1,G6PD,CCDC47,YTHDF2,MAP1LC3B,MLLT6,AGPAT5,UAP1,PPME1,ILF2,CASK,SRP72,EHD4,SEPTIN7,ZC3H11A,HINT1,EMC2,POLL,CTNND1,OLA1,MDC1,GALNT2,EIF3E |
| 9.643e-43 | -96.74 | DDRGK1 (DDRGK domain containing 1) | protein interactions | 65992 | 1235 | 565 | 19454 | 5460 |
FGFR1,SSR1,LUC7L3,CYC1,TFB1M,TFIP11,GTF2H4,CDC42,WDR3,NME4,RPS15,DDX46,RPL27,GRAMD2B,DERL1,GEMIN8,MRPS16,ALKBH5,EXOSC1,IGF2BP1,RPL7A,SLC25A1,CFL1,TXNDC12,RPP25,CDC20,UQCRC2,CDIPT,PTPMT1,RBMX2,SEC61A1,PHAX,SURF4,EXOC3,TP53,RPSA,ATP5PB,STRBP,HNRNPK,CSE1L,RAB3B,PSMA5,RPL17,DHX9,RPL24,SMCHD1,LSM3,ELOC,GAPDH,PPIL4,MIF,PLG,TMED9,CAND1,STX6,LMAN1,ALYREF,RPL32,MRPS9,SSBP1,RAC2,DSTN,CSNK1A1,PSMB3,TOMM22,MRPL12,SEC62,PHB2,EEF1G,SRSF2,TRA2B,FXR2,UFL1,TMEM160,DDX5,SF3B1,PSMD14,MRPS25,CIRBP,CCT2,CKB,RCL1,FIS1,RPS26,LDHB,HNRNPC,PSMA4,HNRNPAB,SNRPB,BTF3,MATR3,RPL10,ESR2,LMBR1L,VDAC2,SMU1,PRMT5,PTRH2,TUBB4B,RPS23,TRMT1L,RPS7,EEF2,TUBA1A,H1-3,DNAJC25,RUVBL1,PSMA2,HNRNPF,PRPS1,RPS4X,ABCF1,RPL31,TRIM21,EWSR1,BPNT2,DDX1,PTDSS1,RAB5C,RPL6,DDX50,LAMP2,DDRGK1,EXOC1,QPCTL,XPO1,SNRPD3,SNRPA1,RPS10,HNRNPL,NOB1,CCT7,HSP90AB1,RBM5,RAB35,RARS1,RPL26L1,TIMMDC1,SEC22B,SF3A1,ST7,BRIX1,SOD1,RPA3,PPIH,KIN,DNAJC19,CDC73,AP2A1,RACGAP1,RPL26,FBXO7,RPP25L,COPE,MGST3,DEK,VIRMA,UQCRQ,POP7,TUBA1B,EIF2AK2,ENO1,RPS12,ALB,ODR4,CMBL,ADAMTS1,LLPH,DHRS7B,VAC14,CCT5,EXOSC8,FCF1,NOC4L,FARSA,PTGES3,SMN1,NKRF,TMED1,TCOF1,IGF1R,RPL23A,NME2,OSBPL8,SPATS2L,ATP5MG,SLC25A46,GRSF1,MOV10,LAMP3,RPL35A,MRPS23,MRPL24,MSMO1,KRR1,PTPN1,RPL12,PSMB1,USP39,KCTD12,ARCN1,SLC25A3,PGRMC1,ACTL6A,NOP53,HSCB,CMAS,STX7,PXMP2,EXD2,YWHAZ,RPS5,CNIH4,PFDN2,HSP90AA1,RPS29,PRPF31,MRPL16,TUBB,PRDX2,EIF4A2,ERH,RPS9,SEC61B,SNRPD1,SNRPD2,EXOSC3,RPN1,SNRPE,RPS11,ERLIN2,PPP2R1A,RPL29,FAF2,UFM1,DHX16,SACM1L,SSRP1,GTF3C3,RPS27A,HNRNPA2B1,SLC25A5,SCYL2,HSPD1,SRSF7,PCNA,OPA3,PPM1B,WDR12,CDK5RAP3,MPHOSPH6,RB1CC1,MRPS26,HNRNPD,ZNF207,HNRNPA1,AGK,DHX15,SRSF10,PPIA,MRTO4,RPL9,RPL8,RPLP2,EIF2B3,IDH2,RPA2,SDCBP,GSTP1,UTP15,CFTR,NTPCR,GTF3C4,MRPL10,MRPL41,HSPA5,MARS1,ZC3H15,EIF4E,TOMM20,BANF1,RAB9A,PRDX6,HNRNPH2,EXOSC4,EIF3G,ELAVL2,ATP1A1,SUB1,RPF2,NCAPG2,RPS17,BUB3,SRPK2,BCCIP,PSMA6,RPS3,EIF2S2,MRPS28,RBM34,IK,TFRC,MTCH2,IPO8,PREB,SRPRB,IMP4,TMEM33,KPNA2,FKBP8,SLC25A11,NOSIP,SLC16A1,MRPS18B,RPL3,SNRNP70,TMEM11,TUBG1,SMAD4,RPL10A,RPS2,CDK12,FAM20C,RBFOX3,RBM17,CMSS1,KARS1,TMA16,SHPRH,NKAP,IFRD2,RPS16,DNAJC1,CDC5L,TMPO,RBM42,DKC1,EEF1B2,SYNCRIP,COQ8A,TLR5,RPL27A,STAU1,HNRNPA0,MRPS7,XRCC5,RFC4,SNRPA,STK26,RAB5A,APPBP2,HSPA8,H1-10,CHTOP,RBM27,FTSJ3,NSA2,DNAJB6,TMED5,PSMD6,PSMD4,ATP5F1B,GTF2F1,CAAP1,RAB4A,SMNDC1,RPL18,MTA2,ZRANB2,RANBP1,TOP3B,KIF2A,NUP42,VDAC1,KRAS,HIGD1C,HNRNPDL,POLDIP3,RPL28,CCT8,PABPC1,RBM3,CYP2C9,SREK1IP1,RTCB,PDIA6,DRG1,RIOX2,LYAR,TCP1,FAM98A,EIF2S1,PAIP1,RMND1,SRSF1,EED,MAGED2,GHITM,LMNA,MRPS34,CDK1,ZNF574,RPLP0,MYL12B,EEF1E1,RPS14,ATG16L1,PSMC4,CNP,SMC4,RPL4,HMGB1,NPM3,EIF5B,PNO1,PRPF4,CSTB,MTDH,SYVN1,CHORDC1,XPOT,CSK,NONO,TUFM,GMPS,PPP1CC,ATP5F1A,SLC25A4,RPL13A,TXN,LDHA,ZNF622,SEC63,RPL22,TECR,EIF4A3,PELP1,ACAT1,RPS20,PRKRA,RTRAF,SRP72,RAD23B,ILF2,GEMIN7,MRPL11,YTHDF2,CCDC47,POP5,RPL15,DDX39A,LBR,THRAP3,HSPE1,PAK1IP1,EIF3E,PRDX4,MRPL22,RPS13,ARF4,ZNF787,H2AC25,SLC25A10,HSD17B10,ZC3H11A,EXOC2,ESYT1,PSMD7,DNAJC7,GLO1,EIF2B2,EIF2B5,TOP1,NOP9,AKAP17A,SRPRA,HACD3,SRP14,AIFM1,PWP2,HSD17B11,ATP5PO,APOBEC3C,MYL6,WDR77,TIMM13,PRDX3,PPP1CB,RND2,OTULINL,G3BP2,PSMC1,COIL,ATP5MK,UPF3B,CCDC86,HADHA,LMNB1,FAS,NTRK3,NOP16,MCM3,RFC5,TOMM40,RBBP4,DYNLL1,RPL7L1,RPL35,UMPS,SNRPB2,TNPO3,RPL19,RAN,FAU,ZNF22,RMDN3,AP2M1,RPL37A,STIM1,GTPBP1,GNB1L,KCTD17,G3BP1,RBBP7,TRIM26,RFC2,HS2ST1,RFC3,MRPS17,PPAN,NDUFA4,TMT1A,TRIP4,MORC2,RPS24,ZC3H7A,RHOG,DDX23,RPL23,RSBN1L,AHSA1,MRPS35,STOML2,MARCHF5,PRPF19,PSMD3,PRDX1,EIF3D,TRA2A,WDR11,ATXN10,RPL7,NOP58,CACYBP,ERLIN1,NDUFS8,MYEF2,PHB1,DNM2,WDR6,THOC2,RPLP1,HP1BP3,XPO5,GJA1 |
| 1.102e-41 | -94.31 | MYC (MYC proto-oncogene, bHLH transcription factor) | protein interactions | 4609 | 3018 | 1161 | 19454 | 5460 |
ACAT1,TRIM24,PRKRA,GSK3A,RTRAF,PELP1,SEC63,ZNF507,RPL13A,TXN,NONO,USP14,TUFM,GMPS,RUNX1,ATP5F1A,NDUFB10,CTSD,XPOT,CCDC22,TADA3,SQSTM1,MTDH,FADS2,PNO1,CSTB,AATF,EIF5B,SPR,MYL12B,SNRPN,SAP30BP,CDR2,NOL7,HSP90B1,PTP4A2,TOX4,CDK1,P3H1,SEC23A,H2AZ1,AIFM1,G6PD,CAV1,SLC25A12,DBT,POLR2I,MAPRE2,TOP1,EIF2B5,HDAC6,GMPPB,NFKB1,DNAJC7,ESYT1,SLC2A1,HSD17B10,HINT1,KLF10,ZC3H11A,SEPTIN7,RING1,EHD4,SLC25A10,EIF3E,SNRPG,MDC1,MRPL22,RNF20,CTNND1,HSPE1,LSM4,GGCT,YTHDF2,CCDC47,MRPL51,SRP72,CASK,RAD23B,STARD13,ILF2,DMAP1,RPL37A,AP2M1,PARP2,ZNF22,FAU,CPSF1,RPL19,RPL7L1,RBBP4,MCM3,RFC5,RIOK2,OTUD7B,USP13,PFDN6,MYO6,CCDC86,RLIM,UPF3B,FTL,G3BP2,UNC45A,PSMC1,NSFL1C,ETF1,EHD1,MYL6,NDUFA5,THY1,HP1BP3,RPLP1,XPO5,OCIAD2,PHB1,LRWD1,ZNF593,ATXN10,RPL7,CCAR2,SPTAN1,OCRL,NOP58,MRPS35,STOML2,MARCHF5,DPY30,PSMD3,PRDX1,RSBN1L,CDH13,LYZ,AHSA1,KDM2A,RHOG,UBE3A,ERP29,RPS24,ATF3,CDKN2C,PCGF6,ANP32B,EIF2D,RFC3,AP1M1,ETFA,G3BP1,LASP1,MAK16,CCS,FEN1,MARCKSL1,AP2S1,PLD3,SF3B5,EIF1AX,EZH2,EIF2S2,KIAA1958,PSMA6,NMI,PPP1R10,RALA,NCAPG2,TIA1,SUB1,NAA50,MAT2A,RPF2,RRP7A,ATP1A1,LSM6,EIF3G,SPOP,PRDX6,THUMPD1,BANF1,POLD2,HSPA5,ZC3H15,TOMM20,MRPL41,KDM1A,NTPCR,NDUFAB1,GTF3C4,CCNH,SUMO1,SPTBN1,PRKCA,UTP15,UBE2M,E2F6,ZNF326,SAMM50,SLC22A8,MCL1,NDUFB4,SDHB,SYNCRIP,CDC5L,SURF6,ILVBL,GRM1,CSNK2A1,TMA16,ACOT8,CMSS1,TMOD2,RPL10A,SNRNP70,TUBG1,ABCE1,SLC16A1,RPL3,NOSIP,MNAT1,IMP4,KPNA2,ACTR1A,GCHFR,CDK4,PSMC3,TAF2,RNF8,ARPC3,RBM34,NFE2L2,IK,CHAMP1,GPD2,GTF2F2,PHF21A,EFHD2,LORICRIN,ZHX3,FBXO22,USP16,PSMD4,RPL39,NSA2,DNAJB6,ELAVL4,CHTOP,RBM27,SPCS3,YAF2,HDAC5,MRPL34,HSPA8,XRCC5,RFC4,SLU7,GNB4,STAU1,HNRNPA0,NDUFAF3,ZNF362,NUP62,RPL27A,NCOA5,MRPS18A,PAK2,MXD1,EED,S100A8,CORO1C,POLR2L,FBXO31,HMG20A,LANCL1,UQCRH,LYAR,TCP1,FAM98A,MEAF6,EIF2S1,STK4,YWHAB,SMAD9,FKBP4,IKBKB,PDIA6,EFNB1,RUVBL2,RPAP3,RBM3,PABPC1,POLDIP3,HNRNPDL,CDCA7L,RPL28,VDAC1,KIF2A,PPIL3,MTA2,GLE1,CTTN,EIF2AK2,ENO1,CTNNA1,MRPL53,CINP,DEK,GNAI2,VIRMA,UBE2L3,ZBTB17,NDN,TMOD3,GMNN,TAF5L,PPIG,PAIP2,AP2A1,PPIH,IDH3A,HELLS,ARMCX1,PPM1G,PRIM2,VPS28,MRPL20,UTP23,CXXC1,LSM8,FBXW7,PDHB,MRPL17,COL3A1,FTH1,KDELR2,SEC22B,NFYB,UBA52,WTAP,SHOC2,MET,DCK,PSMB1,BOK,PRR3,KRR1,MRPS23,CWC15,CDK9,MDM2,MRPL50,IL18,CGAS,SUV39H1,PMM2,SPATS2L,FAM133B,FOXP1,BRD3,ID1,MRFAP1,PQBP1,HUWE1,RNF115,TRIM62,MAP2K3,CD2BP2,CCT5,MAGEA4,RPS9,AP1G2,SNRPD1,POLR3B,GLIPR2,VPS72,GNG12,S100A6,LGALS3,TUBB,MRPL23,RPS29,MRPL16,PKP4,PYCR1,LSM14B,ILK,PFDN4,RPS5,SCFD1,YWHAZ,ZCRB1,BRCA1,FYTTD1,MED10,TERT,EMG1,TXNL1,CMAS,CDSN,YTHDF1,SRI,SRM,ANXA7,ARCN1,SLC25A3,FKBP10,SNX17,MAP1LC3A,PSMB4,MRTO4,RPL9,INA,HNRNPA1,WEE2,HSPB8,BCL7C,PDIA3,SLC25A26,HMGA1,COTL1,MRPS26,HNRNPD,WDR12,ZCCHC9,MRPL18,SRSF7,MRPS11,BAG2,NEK9,SLC25A5,AHCYL1,SSRP1,RPS27A,ATP5F1D,RPL29,ACTN4,JUN,FAF2,ARFGAP1,ANP32A,CKS1B,SART3,RPS11,POLR2C,NME1,EXOSC3,RPN1,MACROH2A1,CALML5,PHAX,CSNK2B,MID1IP1,SF3B6,RSL24D1,RPP25,TXNDC12,CTSB,ALKBH2,SMARCA5,SLC25A1,AKT1,PSMB2,CDKN2AIP,IGF2BP1,MECP2,NLE1,LIN7C,BAP1,WDR3,IGFBP3,AGO1,CSNK1G3,CYC1,LUC7L3,TFIP11,TFB1M,XXYLT1,GATAD1,SLC39A10,RPL32,SSBP1,ACSL4,MRPS9,MXI1,MALSU1,MYL12A,FZR1,CAND1,TMED9,GAPDH,TPM3,PPIL4,COX5A,USP2,MAP4,TAF9,KPNA1,RPL24,DHX9,GPX2,MRPL52,PIK3AP1,RDH11,CSE1L,PSMA5,NUP107,MRPS33,PDE12,NEDD8,TP53,RPSA,STRBP,IMP3,MRPL33,CAPZA2,CDK8,EXOC3,DDX42,MRPL13,DLST,VDAC2,EFNA5,NCKAP1,APEX1,RPL10,CBX5,LRIF1,POLR2B,CPSF2,UFD1,BAG3,PSMD1,KANSL3,LDHB,HNRNPC,MYC,SERPINH1,RCL1,H2AZ2,CIRBP,CCT2,RAMAC,SF3B1,TIMP3,RPS28,NGRN,SERPINB6,EEF1G,PSMB3,EFHD1,CSNK1A1,NUFIP2,EIF4B,MMP14,ACAA2,MTHFS,FUBP3,RBM5,RPRD1A,RPS10,ISG20L2,NOB1,TOR4A,NGDN,EXOC1,QPCTL,DNTTIP1,XPO1,PFDN5,RPL6,DDX50,BAZ1B,LAMP2,FAM168A,TRIM21,EWSR1,MYO1B,BCL7B,RPL31,PAK6,UTP25,PRPS1,DCTPP1,CCAR1,USP30,TFPI,PSMA1,HNRNPF,ELF1,EEF2,TUBA1A,ANAPC13,DHX38,TRMT1L,TAF10,RPS23,PDHA1,TUBB4B,CHCHD6,PTEN,RPS20,UBE2I,GANAB,EIF4A3,STUB1,QNG1,RPL22,SH3BP4,YES1,RAB14,LDHA,PPP1CC,PYCR2,CASC3,TADA1,STK11,EPHA2,PIP4K2C,ARPC2,PRPF4,SS18,MBD3,LDOC1,NHP2,SMC4,HMGB1,RPL4,DGCR8,NPM3,GTF2I,SGF29,CNP,ELP3,RBMS2,COMMD3,PSMC4,RPS14,RBFOX2,CPSF4,MACROH2A2,TMOD1,RPLP0,JUP,LMNA,MRPS34,PWP2,RCHY1,SRP14,ETV6,SRPRA,HACD3,AKAP17A,PRNP,PPP1R18,LRRC40,CRADD,MPG,EXOC2,MPHOSPH10,PSMD7,TIAM1,PC,SNAP23,ZNF787,MSH6,PRDX4,RPS13,ARF4,TF,THRAP3,CAMK2G,PAK1IP1,CTNNBL1,RPL15,EEF1A1,LBR,DDX39A,MRPL11,PDLIM4,FBXO8,MRPL49,RAN,PELO,GNB1,SNRPB2,OTUD6A,CHCHD3,RPL35,TSN,DYNLL1,RBM15B,MCM4,RHEB,RNF40,NOP16,RIT1,SP1,LMNB1,BLVRA,HADHA,NUP50,PMAIP1,THOC3,SKP1,COIL,GPC1,MCMBP,MLH3,PRDX3,TIMM13,SUPT3H,IDH3B,PPP1CB,H1-5,WDR77,RTF2,ADNP,ATP5PO,APOBEC3C,MYEF2,WDR6,CBFB,THOC2,CETN2,CACYBP,CGGBP1,ERLIN1,EIF3D,TRA2A,WDR11,PRPF19,CLPX,TAF7,CD58,RPL23,CDKN1B,HBA1,DDX23,CSTA,ZC3H7A,ARGLU1,PPAN,MEF2C,DNTT,RFC2,MRPS17,MCM6,RBBP7,ASPM,GFPT1,NUP153,E2F4,GTPBP1,RBPJ,KBTBD3,ABHD14B,PSMC5,MRPS28,LIG3,UBN1,RPS3,SUCLG2,GABPA,BUB3,MRPS21,PCBD1,RPS17,MORF4L1,CALU,ELAVL2,CCDC174,DNAJC10,NR0B1,CWF19L1,HNRNPH2,UGDH,MARS1,MRPL40,RBM22,NEK2,SNRNP27,MRPL10,CAPN1,HOXB8,SLC35F6,ACACA,GSTP1,HEXIM1,EIF2B3,RPRD1B,SFRP1,COMT,EEF1B2,RBM42,TMPO,DKC1,EPHB6,NKAP,RPS16,MZT2B,RBM17,KARS1,RPS2,CDK12,RAB13,MRPS18B,SLC25A11,SNIP1,PALM2AKAP2,CAPZA1,SRPRB,TMEM33,CDC40,ZMYM3,WBP11,MRPL47,RRM1,NAA35,SRFBP1,TBC1D4,MRPL36,TFRC,GTF2F1,SF3B4,PHF12,SNRNP40,ATP5F1B,PCCB,PRSS1,POLR1B,MCAT,THOC6,H1-10,FTSJ3,EP300,RAB5A,FLYWCH2,SNRPA,HIRA,PYM1,MRPS7,SAP18,OXCT1,GON7,SOX3,NEK7,CD59,PAFAH1B1,CTBP1,ADSS2,PLAA,MAGED2,SRSF1,SDC4,FABP5,DYNC1I2,TRIR,PAIP1,IQSEC1,UTP6,PPIB,MRPL9,RIOX2,DRG1,HSPB1,CASP12,CNTFR,ACTR1B,SREK1IP1,RTCB,DNAJB4,CCT8,TOP2B,H1-6,KRAS,OAZ2,TRAF2,SUPT5H,RANBP1,PRSS35,UBL5,MAX,RPL18,CRKL,RHOBTB1,ZRANB2,SMNDC1,RPS12,MSN,ALB,GTF2A1,TUBA1B,METAP2,JUNB,FERMT2,UBB,RPP25L,PNP,DNAJC8,HMOX2,RACGAP1,RPL26,CIAO1,ZNF687,COL1A2,ANKIB1,CDC73,SMAD2,SDF2L1,KIN,RPA3,BRIX1,NF2,UQCRC1,MED30,ADIPOR1,PCK2,SF3A1,CARHSP1,RPL26L1,RARS1,HNRNPH3,DCTN4,RB1,MYBL2,SMAD3,PTPN1,RPL12,MRPL24,NCBP2,THOC1,RPL35A,ERCC3,GRSF1,MOV10,CNN3,EIF5A2,CCNY,RPL23A,CPNE2,SFXN1,TCOF1,NKRF,PPP1R12A,RAB1A,RIGI,VPS16,PAGR1,FASTKD5,VTA1,MRPS18C,NOC4L,CDK2AP2,TRIM63,B4GALT7,TSSC4,AURKAIP1,TRIM6,NDUFA2,TBC1D19,ACTR2,NDUFS3,LLPH,ZMAT2,POLR2F,SNRPD2,ERH,CLIC4,PRRC2A,USP5,ACTB,MED17,RPF1,PRDX2,PRPF31,SMARCE1,ACO2,HSP90AA1,PFDN2,PSMA3,NKAPD1,AZGP1,PYGB,CSRP1,RP2,MRPL57,NOP53,SUPT4H1,CDKN1A,ACTL6A,MFAP1,ISOC1,LARP4B,USP39,CETN3,RPLP2,KRT8,PSMB5,RPL8,DHX15,PPIA,SRSF10,ZNF207,VPS26A,PPP2R5A,VPS4A,HECTD3,PCNA,MKLN1,HNRNPA2B1,HSPD1,RAD21,GTF3C3,ASF1A,S100A10,DHX16,ZNF592,NFE2L1,PPP2R1A,NEU1,CSNK1E,NAA15,VDR,BUD23,RAF1,SNRPE,POLR2D,ITGB5,RAB6B,CTNNA2,SRP54,SEC61A1,UQCRC2,PSPC1,CDC20,EIF4H,CFL1,RPL7A,SUGP1,TRIM32,RBM7,SORD,OAT,CHCHD4,MRPS16,GFM1,DERL1,CCDC65,SNX33,DLAT,PGK1,LSM12,RAB29,PML,RPL27,GRPEL1,RPS15,HDAC3,AIF1L,CDC42,POLR1D,GTF2H4,SUPT7L,SSR1,NT5DC1,CDK6,DSTN,ALYREF,METAP1,CD2,RPS27L,MIF,BRMS1L,GNG2,USP3,ENY2,NOL12,AKAP8L,SMG8,SMCHD1,MED27,ZNF451,PSME1,MAP1B,RPL17,MEPCE,HNRNPK,GNPNAT1,ESS2,GNAI3,HBP1,CAPN2,CBX3,PIK3CA,RP9,ZMYM2,SMU1,RRAS2,MIDEAS,PAPSS2,PSMB6,MANSC1,STAT1,MATR3,TAGLN2,SNRPB,BTF3,PSMA4,SFN,HNRNPAB,COX6B1,CREBBP,H1-1,TRIB1,OAZ1,RPS26,S100A11,MRPS25,CKB,DDX5,SPECC1L,BMPR1A,DDX39B,SMARCD3,GINS3,PHB2,TRA2B,SRSF2,FXR2,NDUFS2,MRPL12,ZC3H14,LAP3,MAP2K1,PPT1,WDR82,SIN3A,CCT7,CHMP2A,HSP90AB1,SNRPD3,SNRPA1,SUMO2,HNRNPL,RAB1B,CTNNB1,YWHAG,RAB5C,WWP2,IFI16,MAGOH,DDX1,ABCF1,LSM14A,RAB18,IMPA2,TFG,RPS4X,RUVBL1,PSMA2,RPS7,PI15,SMARCB1 |
| 1.137e-39 | -89.67 | PHB1 (prohibitin 1) | protein interactions | 5245 | 1092 | 505 | 19454 | 5460 |
PLAA,UBAC2,PIH1D1,RPL27A,GOSR2,YIPF5,SEC22A,EMC1,HNRNPA0,SSR3,STAU1,MRPS7,LCA5,SNRPA,FOS,XRCC5,HSPA8,HDAC5,AKAP1,EP300,H1-10,ICAM1,THTPA,DNAJB6,ARMC7,RPL39,PCCB,ATP5F1B,PSMD4,FBXO22,TACO1,CCDC90B,SF3B4,UCK2,RAB4A,SMNDC1,KLHL12,AAMP,RPL18,TOP3B,KRAS,VDAC1,RPL28,HNRNPDL,PABPC1,CCT8,RBM3,RUVBL2,PDIA6,RTCB,AGR2,HSPB1,YWHAB,DRG1,EIF2S1,FAM98A,TCP1,RHOH,UQCRH,RMND1,SRSF1,CORO1C,EED,VPS4B,RPA2,HEXIM1,TRAM1,GTF3C4,NTPCR,CFTR,MRPL41,SLC25A51,MARS1,HSPA5,HNRNPH2,PRDX6,DNAJC10,ATP1A1,ELAVL2,FGFR1OP2,MAT2A,RPS17,TIA1,NCAPG2,BUB3,PPAT,RPS3,PSMC5,EIF2S2,TFCP2,TMEM165,RBM34,ACADSB,RNF8,UBL4A,MTCH2,TNRC6C,CDK4,KPNA2,TMEM33,SRPRB,CAPZA1,SLC25A11,RPL3,SLC16A1,TUBG1,SNRNP70,RPS2,RPL10A,USP15,KARS1,ACOT8,CCL5,COPS5,RPS16,VPS26C,TMPO,CDC5L,STT3A,CD274,EEF1B2,SYNCRIP,COX4I1,NDUFB4,CD4,ATP5PO,MED23,NDUFA5,MTX2,RND2,PRDX3,COIL,G3BP2,SKP1,UPF3B,ATP5MK,HACD1,PMAIP1,HADHA,RIT1,CUL3,NOP16,SAMHD1,RHEB,RFC5,TOMM40,MCM4,MCM3,RBBP4,RPL35,UMPS,MAD2L1,CHCHD3,PARL,RPL19,CHP1,CYB5R3,RAN,RPL37A,EZH2,BPIFB1,GTPBP1,PLD3,TPD52,GFPT1,YIPF3,CYB5R1,TRIM26,G3BP1,TRIM37,MCM6,RFC2,RPS24,RHOG,TRAF6,AHSA1,RPL23,PRDX1,CLPX,STOML2,ATG7,WDR11,NOP58,RPL7,NDUFS8,ERLIN1,DNM2,WDR6,FOLR1,PHB1,HP1BP3,RPLP1,GATD3,CYB5A,CDK1,JUP,MRPS34,LMNA,HSP90B1,RPLP0,MTRES1,RPS14,ATG16L1,PSMC4,RBFOX2,CNP,EIF5B,RPL4,NHP2,MTDH,H2BC12,SQSTM1,XPOT,CASC3,NDUFB10,ATP5F1A,TUFM,NONO,AR,LDHA,RPL13A,TECR,SMAD5,RPL22,STUB1,SCAMP2,EIF4A3,RTRAF,GANAB,PTEN,RPS20,ILF2,MRPL49,CCDC47,YTHDF2,MRPL11,DDX39A,EEF1A1,LBR,RPL15,ARF4,OLA1,RPS13,SNRPG,SLC25A10,BSCL2,EMC2,HSD17B10,DNAJC7,CALR,GMPPA,HDAC6,TOP1,ATP5PD,SLC25A12,ZBTB2,CAV1,AIFM1,SRP14,HACD3,ARL10,HSD17B11,SEC23A,PPT1,NUFIP2,CAV2,TRMT112,TOMM22,MRPL12,NDUFS2,UFL1,SRSF2,EEF1G,ADRB2,PHB2,DDX39B,RPS28,SF3B1,RAMAC,DDX5,CCT2,CIRBP,RPS26,COP1,SERPINH1,MYC,HNRNPAB,LDHB,HNRNPC,PSMA4,SNRPB,TAGLN2,MATR3,POLR2B,RPL10,ESR2,VDAC2,LMBR1L,DLST,PRMT5,SMU1,GGT7,TUBB4B,PDHA1,RPS23,EEF2,RPS7,HNRNPF,RUVBL1,RPS4X,PRPS1,TFG,RAB18,RPL31,ABCF1,TRIM21,EWSR1,MGMT,CBL,DDX1,PEX3,IFI16,RPL6,WWP2,RAB5C,PTDSS1,XPO1,DDRGK1,HNRNPL,RPS10,RAB1B,SNRPA1,SNRPD3,HSP90AB1,CCT7,SIN3A,WDR82,SSR1,HIKESHI,FGFR1,TFB1M,LUC7L3,CYC1,CDC42,RPS15,GRPEL1,RPL27,MAIP1,LSM12,GFM1,SMG5,ATP1B3,RIC3,IGF2BP1,OAT,UBE2H,RAB2A,SLC25A1,RPL7A,CFL1,CTSB,CDIPT,SF3B6,PSPC1,UQCRC2,PHAX,SURF4,SLC25A24,TP53,RPSA,APOO,METTL15,HNRNPK,MEPCE,RPL17,MAP1B,DHX9,BCAP29,TMEM70,H2AC4,CHCHD1,RPL24,AKAP8L,SMG8,MAP4,DPP4,COX5A,CAND1,FZR1,RPS27L,LMAN1,MYL12A,ACSL4,SSBP1,RPL32,UBE2G2,ALYREF,RAC2,VAPB,KLF3,USP39,LARP4B,SLC25A3,PGRMC1,TOR1AIP2,RNF11,BIRC2,PSMA3,EMG1,RHOB,YWHAZ,HSP90AA1,RPS5,HTRA2,MTG2,PMPCA,RAB11A,PRDX2,TENT5C,TUBB,ACTB,PRRC2A,SNRPD2,SNRPD1,SEC61B,RPS9,RPN1,NDUFS6,RPS11,SNRPE,RAF1,RPL29,ERLIN2,ASF1A,HSPD1,SLC25A5,HNRNPA2B1,PRPSAP1,PCNA,SKIC8,HNRNPD,HAX1,HNRNPA1,AGK,PPIA,SRSF10,DIRAS3,DHX15,RPL8,RPL9,MAP1LC3A,TYMS,ATP6V1A,RPLP2,COX6C,STOM,METTL14,RARS1,HNRNPH3,KDELR2,UQCRC1,CDK7,NF2,PDHB,BRIX1,RPA3,KIN,RAB33B,SDF2L1,DNAJC19,GGCX,RALB,RPL26,HMOX2,COPE,RHOJ,UBB,UQCRQ,VIRMA,CCNF,EIF2AK2,ENO1,TUBA1B,POP7,ACTR2,NDUFS3,DHRS7B,CCT5,HUWE1,FARSA,FASTKD5,RAB1A,FAF1,SFXN1,RPL23A,POR,GRSF1,ATP5MG,ATP1B1,RPL35A,NCBP2,PTPN1,RPL12,RB1,PSMB1 |
| 1.307e-39 | -89.53 | NR2C2 (nuclear receptor subfamily 2 group C member 2) | protein interactions | 7182 | 1393 | 612 | 19454 | 5460 |
GTPBP1,SF3B5,NUP153,MAK16,FEN1,RFC2,SRSF4,MRPS17,MCM6,AP1M1,ETFA,RBBP7,SRSF8,RPS24,PPAN,ARGLU1,TMT1A,NDUFA4,RPL23,SLC25A21,RSBN1L,AHSA1,HBA1,TRAF6,RHOG,DDX23,TRA2A,EIF3D,STOML2,MRPS35,DPY30,CLPX,PSMD3,PRPF19,PRDX1,HMBS,ERLIN1,CACYBP,MPP1,SNX2,BUD31,CCAR2,RPL7,NOP58,HP1BP3,RPLP1,XPO5,PHB1,SP2,DNM2,THOC2,NDUFA5,MYL6,ADNP,APOBEC3C,ETF1,H1-5,WDR77,PSMC1,COIL,NSFL1C,HADHA,NUBP2,LMNB1,BLVRA,MCM3,MCM4,RHEB,RFC5,TOMM40,RIOK2,CFAP20,SNRPB2,TNPO3,RPL19,MAD2L1,RPL7L1,RPL35,DYNLL1,RBBP4,RPL37A,AP2M1,RAN,UBE2S,PARP2,PELO,EIF3K,ELK3,FAU,SRP72,MRPL49,ILF2,PPME1,AGPAT5,RPL15,NECAP2,EEF1A1,LBR,DDX39A,CCDC47,MSH6,EIF3E,PRDX4,RPS13,MRPL22,ARF4,TF,THRAP3,SLC25A32,CTNNBL1,PAK1IP1,PC,HSD17B10,NSDHL,SLC25A10,ESYT1,PSMD7,MPHOSPH10,SLC2A1,LRRC40,CALR,SLC25A12,DBT,AKAP17A,TOP1,MAPRE2,ARF6,PWP2,SRP14,SRPRA,HACD3,H2AZ1,AIFM1,PAX9,OXSR1,NOL7,RPLP0,HSP90B1,TOX4,CDK1,TIMM23,LMNA,SAP30BP,RPS14,PSMC4,AATF,NHP2,SMC4,HMGB1,RPL4,NPM3,EIF5B,GTF2I,MTDH,FADS2,PNO1,PRPF4,IRAK1BP1,CASC3,XPOT,CA2,PIP4K2C,CHORDC1,KPNA6,AR,NONO,GMPS,TUFM,ATP5F1A,RPL22,SEC63,TENT2,TECR,ARMC6,SNX3,SLC25A4,RPL13A,RAB14,MAGOHB,LDHA,ACAT1,RPS20,RTRAF,GANAB,GSK3A,EIF4A3,QNG1,RPL18,MTA2,CAAP1,IRF8,KIF2A,SOX2,TRAF2,RANBP1,UBL5,HNRNPDL,PAX6,RPL28,H1-6,SREK1IP1,RTCB,RUVBL2,TOP2B,PABPC1,CCT8,DRG1,HSPB1,IKBKB,IQSEC1,UTP6,PPIB,GSTM3,LYAR,TCP1,FAM98A,EIF2S1,EED,SRSF1,POLR2L,MPDU1,FDFT1,CTBP1,PAK2,RPL27A,MRPS7,SAP18,SSR3,UBE2D3,HNRNPA0,RAB5A,HSPA8,XRCC5,HIRA,SNRPA,NSA2,PRSS1,POLR1B,DNAJB6,H1-10,FTSJ3,RBM27,PCCB,MLF2,HMGCS1,TMED5,SNRNP40,USP16,ATP5F1B,SF3B4,PSMC3,TAB2,RBM34,TMEM165,TFRC,EGR2,GLRX5,H2AX,SRPRB,RBCK1,IMP4,KPNA2,TMEM33,CDC40,ABCE1,SLC16A1,RAB13,RPL3,SLC25A11,SNIP1,RPL10A,RPS2,SNRNP70,TUBG1,CSNK2A1,KARS1,CDC5L,KLF9,TMPO,ILVBL,DKC1,NKAP,RPS16,IFRD2,SYNCRIP,EEF1B2,STT3A,ACACA,UBE2M,UTP15,ZNF326,EIF2B3,IDH2,WRAP53,RPA2,HSPA5,POLR1H,MARS1,RBM22,KDM1A,PRDX6,LCP1,HNRNPH2,BANF1,POLD2,RRP7A,RC3H2,EIF3G,CEP85,GSTK1,SUB1,RPF2,MAT2A,BCCIP,SUCLG2,GABPA,BUB3,GTF2H2,ABHD14B,PSMC5,EIF2S2,ING2,PSMA6,UBN1,PAFAH1B3,RPS3,DOHH,SNRPE,RPS11,PRKAG1,RAB6B,RPN1,RPL29,HSDL2,RAD21,SSRP1,RPS27A,PSMD12,ASF1A,DHX16,MRPS11,SRSF7,BAG2,PCNA,HNRNPA2B1,SLC25A5,HSPD1,LHX2,HNRNPD,WDR12,SKIC8,HNRNPA1,VPS26A,DHX15,PRKCQ,SRSF10,PPIA,RPLP2,ATP6V1A,BRD9,TYMS,MRTO4,RPL9,KLHL7,RPL8,ARCN1,SLC25A3,MFAP1,KLF3,NOTCH2,ACTL6A,TERT,TXNL1,NKAPD1,RPS5,SCFD1,HSP90AA1,YWHAZ,ATF1,PRPF31,MRPL16,PYCR1,ACO2,TAB1,ACTB,TUBB,EIF4A2,PRDX2,RPS9,SNRPD1,SNRPD2,RSRC1,S100A6,NDUFS3,ACTR2,LLPH,FCF1,MAP2K3,CCT5,CMPK1,PTGES3,ADD2,FASTKD5,NOC4L,FARSA,VRK1,HUWE1,RPL23A,SFXN1,NKRF,TCOF1,RAB1A,OSBPL8,ATP5MG,FAM133B,GRSF1,MOV10,MRPL24,CWC15,MSMO1,NCBP2,CGAS,RPL35A,DCK,KRR1,RPL12,RARS1,HNRNPH3,ZCCHC17,STOM,KLF12,PCK2,SF3A1,BRIX1,UTP23,PDHB,PRKCB,IDH3A,DVL2,RPA3,PPIG,AP2A1,FBXO7,RPL26,ZNF687,DEK,GNAI2,UQCRQ,UBB,RPS12,ALB,METAP2,ENO1,EIF2AK2,RPS23,TAF10,SMARCB1,PDHA1,TUBB4B,RPS7,EEF2,TUBA1A,H1-3,DHX38,ETFB,TRMT1L,PRPS1,CCAR1,RPS4X,RUVBL1,PELI1,HNRNPF,EWSR1,ABCF1,S100B,RPL31,DDX1,DRG2,GSTO1,NGDN,ZCCHC10,PTDSS1,RAB5C,RPL6,DDX50,BAZ1B,HSP90AB1,SNRPA1,AASDHPPT,SUMO3,SNRPD3,HNRNPL,ECHDC1,NOB1,WDR82,FUBP3,GYS1,CCDC71,TRMT112,CNDP2,MAP2K1,LXN,ATP6V1C1,TOMM22,LAP3,LYPLA2,PHB2,EEF1G,TRA2B,SRSF2,FXR2,UFL1,DDX5,SF3B1,RPS28,PEBP1,DDX39B,SERPINH1,RCL1,RPS26,PSMD14,MRPS25,CCT2,SNRPB,CPSF2,KANSL3,BTF3,PSMA4,HNRNPC,LDHB,HNRNPAB,APOBEC3B,ALG5,RPL10,CBX5,LRIF1,POLR2B,STAT1,TAGLN2,TAMM41,MATR3,PRMT5,VDAC2,CAPZA2,SURF4,CBX3,RP9,ESS2,RPSA,IMP3,RPL17,MEPCE,HNRNPK,H3C1,DHX9,MAP4,TAF9,AKAP8L,KPNA1,RPL24,SMCHD1,TPM3,GAPDH,TSPO,LMAN1,RPS27L,TMED9,CAND1,RAC2,G6PC3,ADD1,RPL32,UBE2N,METAP1,MRPS9,LUC7L3,TFIP11,HBB,POLR1D,CD2AP,GTF2H4,RPS15,WDR3,HDAC3,DERL1,LSM12,PML,DDX46,BAP1,RPL27,CDKN2AIP,OAT,PDCD4,IGF2BP1,ST13,CFL1,NUDT1,RPL7A,NUDT4,SMARCA5,RAB2A,SLC25A1,RSL24D1,STAT5A,HPF1,MACROH2A1,RBMX2,SEC61A1,CSNK2B,UQCRC2,PSPC1,SF3B6 |
| 4.436e-39 | -88.31 | PRKN (parkin RBR E3 ubiquitin protein ligase) | protein interactions | 5071 | 3398 | 1271 | 19454 | 5460 |
INA,AGK,KIAA0232,NUF2,RPL9,PSMB4,ATP6V1A,SNX17,BRD9,WDR12,ELP6,CDK5RAP3,SKIC8,HNRNPD,PDIA3,DYRK1B,MAP1S,PTPN5,HNRNPA1,RPS27A,UBE2A,PSMD12,AHCYL1,SSRP1,NEK9,SLC25A5,PREPL,SCYL2,ZYX,GPAA1,MAEA,THNSL1,SRSF7,BAG2,RPN1,PRKAG1,BZW2,NME1,RPS11,POLR2C,UCKL1,SART3,HSDL2,DCAKD,ARFGAP1,RBM12,ACTN4,RPL29,FAF2,EIF4A2,LGALS3,TUBB,ABHD12,GPR37,TRMT6,POLR3B,RPS9,YWHAZ,BRCA1,RPS5,ARMT1,HTRA2,NLRP3,ILK,CDC123,PYCR1,F2,PMPCA,MRPL16,RPS29,UCHL3,PPP2R2C,SRI,RADX,SRM,CMAS,CCND3,TBC1D24,DNAJC3,PRKD3,SNRK,BIRC2,TERT,VAPB,H2AC1,ARCN1,ANXA7,SLC25A3,RRAGA,STXBP1,CGAS,CDK9,TOMM70,MDM2,MRPS23,RLIG1,KRR1,PSMB1,POR,NME2,FOXP1,PMM2,HUWE1,ERLEC1,TTC4,PTGES3,FAF1,SNAPC3,IGF1R,TNFAIP8L1,ITGB8,POLR2G,CCT5,MAP2K3,MGST3,UBE2L3,DEK,GNAI2,CINP,CTTN,ENO1,EIF2AK2,CTNNA1,SLC11A2,AP2A1,BRAP,FBXW7,MRPL20,DVL2,HELLS,PPM1G,PRIM2,IDH3A,PRKCB,RAB33B,NUDT12,SLC12A2,STOM,KRT7,STAMBP,AGAP1,PIP5K1A,SEC22B,UBA52,UBLCP1,RPS10,NOB1,AASDHPPT,FHIP1B,RAB35,FUBP3,GYS1,PABPC1L,MT1M,CRTAP,DDT,DENND6B,INPP4A,RPL6,XPO1,YWHAH,EXOC1,QPCTL,PSMA1,USP30,HNRNPF,CCAR1,MX2,SESN3,PRPS1,UTP25,GNA11,RPL31,FBXO3,EWSR1,TRIM21,MYO1B,TUBB4B,PDHA1,DCUN1D5,HGS,RPS23,TRMT1L,DHX38,GCLC,ETFB,TUBA1A,NUDCD3,EEF2,HDDC2,PCMTD1,POLR2B,NCKAP1,APEX1,RPL10,DDIT4,VDAC2,KTI12,DLST,MRPL13,CIRBP,CCT2,FBXW11,ATG3,H2AZ2,ZMPSTE24,SERPINH1,LDHB,HNRNPC,PSMD1,CPSF2,BAG3,LRRC8C,UFL1,SERPINB6,EEF1G,TAPBP,GPHN,SF3B1,GSTM2,ACAA2,NUFIP2,EIF4B,CSNK1A1,TRMT112,CNDP2,MTMR6,ATP6V1C1,TOMM22,PSMB3,SEC62,QTRT2,TBCEL,FZR1,PLG,CAND1,ESD,MYL12A,ACSL4,SSBP1,MRPS9,RPL32,RPL24,KPNA1,TRMT5,TSNAX,COX5A,AMY2B,PPIL4,GAPDH,ELOC,LYPLAL1,TPM3,API5,POLR3GL,ATP1A2,PSMA5,NEDD8,PDE12,CSE1L,CLPB,GALNT12,DHX9,CDK8,SURF4,DDX42,CAPZA2,BIRC5,RAD1,SLC25A24,RPSA,TP53,MAP3K3,DAPK3,IDE,DYRK1A,UBA3,ALG2,CSNK2B,PPP2R5E,MACROH2A1,DTL,IGF2BP1,PDCD4,CDKN2AIP,SMARCA5,CARS1,SLC25A1,AKT1,PSMB2,ETFBKMT,PRKACB,CFL2,WDR3,CLU,DDX46,LIN7C,NLE1,TXNDC17,WWP1,TFB1M,CYC1,LUC7L3,CSNK1G3,PAAF1,KIF3B,OCRL,NOP58,ATXN10,CCAR2,SPTAN1,RPL7,SNX1,NTMT1,DNM2,PHB1,XPO5,TSG101,RPLP1,HP1BP3,RHOG,PSMD10,AHSA1,NQO1,BCL2L1,PSMD3,HMBS,UBXN6,PRDX1,STOML2,MRPS35,MARCHF5,ATG7,G3BP1,LASP1,ETFA,GNL1,PPWD1,AP1M1,RFC3,NDUFA4,AKAP14,SLC39A7,RPS24,STIM1,EZH2,EIF1AX,AP2S1,OTULIN,FEN1,MARCKSL1,ACO1,MAK16,RBBP4,RPL19,CD79B,CPSF1,EIF3K,CYB5R3,RMDN3,AP2M1,RPL37A,MYO6,CBR3,CFAP20,CUL3,SCN3B,RFC5,SAMHD1,RIOK2,MCM3,GALE,TSR3,NPTN,ATAD1,PSMC1,POLA2,ARL6,UNC45A,G3BP2,ATP5MK,RAB40AL,TRUB1,NUBP2,MYL6,EHD1,ETF1,TOP1,EIF2B5,DBT,G6PD,SLC25A12,SSU72,DFFA,AIFM1,HSD17B11,SEC23A,SLC2A1,ESYT1,DNAJC7,NFKB1,ERV3-1,EI24,HDAC6,HSPE1,RNF20,MRPL22,OLA1,CTNND1,SNRPG,EIF3E,MDC1,EHD4,SLC25A10,GLUL,ZC3H11A,SEPTIN7,HINT1,HSD17B10,TMX3,NTRK2,UAP1,HSPA13,CREB3L4,ILF2,PPME1,RAD23B,CASK,SRP72,SERPINB9,CCDC47,PHF23,YTHDF2,MAGOHB,TXN,RPL13A,HOMER1,TECR,SEC63,INPP5K,CYRIB,SMAP2,PRKRA,RTRAF,GSK3A,ACAT1,XPOT,CSK,SEC13,ATP5F1A,NONO,TUFM,USP14,GMPS,EIF5B,USP8,FADS2,PNO1,SLC2A3,CSTB,AKR1E2,SQSTM1,MAVS,GPX4,P3H1,CDK1,TMX4,HSP90B1,TTI2,ATG16L1,TPT1,MYL12B,EDF1,EHD3,EIF3J,FAM98A,EIF2S1,AFTPH,RHOH,LYAR,TCP1,CCDC181,LANCL1,SERPINC1,EED,S100A8,CORO1C,FKBP4,YWHAB,DIRAS2,UBE2E2,FAM20B,TRIM34,STK4,GAS8,VDAC1,RPL28,HNRNPDL,PABPC1,RUVBL2,GALC,PDIA6,MTA2,NAA16,TOP3B,KIF2A,CSTF2T,PSMD4,PSMD6,FBXO22,SPCS3,PLA2G15,GCC1,GTPBP2,TBCE,PAPOLA,LDB1,HMGCS1,UBE2D3,HNRNPA0,STAU1,EYA3,GNB4,RANBP10,RNF41,RFC4,SLU7,XRCC5,P4HA2,HSPA8,STK26,MRPS18A,PAK2,KLC2,NCOA5,RPL27A,PABPC5,NUP62,GNPTG,VPS26C,ILVBL,CDC5L,SLAIN2,AIP,SDHB,SYNCRIP,NDUFB4,MCL1,PREP,TUBG1,BECN1,SNRNP70,RPL10A,TMOD2,RBFOX3,CSNK2A1,RBCK1,KPNA2,TOLLIP,NAE1,NOSIP,ABCE1,SLC16A1,RPL3,IDH1,MAN1A2,CHAMP1,GPD2,ACADSB,DNAJC2,NEFL,NHERF1,IK,PSMC3,RNF8,PREB,CDK4,IPO8,HADH,ACTR1A,PYGM,RALA,GMDS,ADRM1,PPP1R10,CSTF3,DUSP3,TRAF1,CREB1,PSMA6,PAFAH1B3,EIF2S2,CRLF3,EIF3G,ATP1A1,PTTG1,SERPINB1,SNX5,PSMG3,MAT2A,MGST2,PTPN11,TIA1,UBE2K,ZC3H15,HSPA5,APMAP,THUMPD1,POLD2,PRDX6,RNF113A,WRAP53,VPS4B,ZNF326,VIPAS39,SAMM50,IDH2,PRKCA,UTP15,UBE2M,SPTBN1,AKR7A2,SUMO1,GTF3C4,SMYD3,NTPCR,CFTR,SNX18,PPIA,DHX15,WDR44,RPL8,PSMB5,TYMS,KRT8,RPLP2,PPM1B,DCAF11,VPS4A,DICER1,SLC20A1,VPS26A,PPP2R5A,IFIH1,ACTL6B,ZNF207,DHX16,GTF3C3,SACM1L,FLOT1,COPS4,HSPD1,BCKDK,HNRNPA2B1,HECTD3,PCNA,PRPSAP1,RAB6B,GDI2,MTMR2,MATCAP1,NAA15,CSNK1E,GIN1,NEU1,PPP2R1A,ERLIN2,STARD7,PRDX2,ACTB,TAB1,MED17,TENT5C,MAT2B,NDUFAF4,CLIC4,USP5,PRRC2A,GRIA1,RAB28,SNRPD2,SEC61B,CNIH4,BAX,HSP90AA1,SETD7,NIBAN2,AUH,ACO2,TMED4,PRPF31,SMARCE1,PAFAH1B2,PYGB,CSRP1,ATP6V1G1,EXD2,PSMA3,USP39,CRYAB,PSMB7,ARMCX3,MAPKAPK5,ACTL6A,TOR1AIP2,CDKN1A,RPL35A,MRPL24,SMAD3,PTPN1,RPL12,ACTA2,TES,NAA30,ECD,ASIC2,SMG9,CNN3,CLP1,OSBPL8,ERCC3,GRSF1,MOV10,HM13,ATP1B1,TMBIM6,TSSC4,FRMD8,FARSA,VRK1,FASTKD5,VTA1,RIGI,VPS16,ADD2,PPP1R12A,HHIP,SFXN1,TCOF1,NKRF,RPL23A,LIPA,ACTR2,NDUFS3,VAC14,AP1S2,DHRS7B,SERPINA1,FBP1,CMPK1,TOR3A,GBE1,TRIM6,MTARC2,PGM1,FNTB,UBE2V1,COPE,PNP,TENT4A,FERMT2,UBB,CEP97,FAH,WDSUB1,GXYLT1,TUBA1B,METAP2,TRIM27,CMBL,RPS12,CTU1,MSN,RAB3C,ODR4,ALB,CDC73,SMAD2,HSPA14,STK38L,CIAO1,RPL26,FBXO7,RACGAP1,ARMCX5,CHMP2B,BRIX1,ZKSCAN1,TCEA1,RTN4,SPCS2,DCTN4,PICALM,GOLGA5,MMP28,CARHSP1,RPL26L1,RARS1,HNRNPH3,PCK2,SF3A1,ARHGAP1,UQCRC1,CDK7,ST7,RAB1B,DBR1,HNRNPL,SNRPD3,OSBP,CCT7,HSP90AB1,PSME2,SIN3A,HDHD5,SWAP70,METTL25B,WDR82,DRG2,CDC23,MGMT,DDX1,CBL,ASB7,ARMC8,IFI16,TSPAN10,PTDSS1,RAB5C,YWHAG,CTNNB1,PSMA2,XPNPEP1,ROCK2,RUVBL1,SLC20A2,RPS4X,TFG,ALKBH4,ABCF1,LSM14A,CDK5,CSRNP3,PLS3,HEXA,H1-3,RPS7,NUP37,TAGLN2,MATR3,TAX1BP1,PSMB6,ACAP2,PAPSS2,DLG4,SMU1,PRMT5,CKB,PSMD14,MRPS25,CYP3A43,FIS1,RPS26,MDH1,PSMA4,SFN,HNRNPAB,SNRPB,RALGAPA2,FXR2,SRSF2,TRA2B,NDUFS2,PHB2,ARMCX2,GINS3,DDX39B,DDX5,MAP2K1,AKR1A1,PACRG,PTAR1,ACSS2,LAP3,TMC7,MRPL12,CPNE1,RPS27L,MIF,LMAN1,CHGA,METAP1,UBE2G2,UBE2N,ADD1,RAP1B,DSTN,NT5DC1,AKAP8L,ATP6V1D,EDC3,HNRNPK,MEPCE,MPST,RPL17,MAP1B,PSME1,YIF1A,CBX3,DISC1,CAPN2,MVD,ATP5PB,HPF1,CHMP5,CDC20,PSPC1,UQCRC2,SRP54,PITPNB,SEC61A1,PTPMT1,INTS12,MRPS16,CISD1,UBE2E3,BICD2,OAT,CSGALNACT1,SORD,UBE2H,TRIM32,RPL7A,CCNB1,CFL1,ST13,GORASP2,HDAC3,AIF1L,STK38,UGP2,RGS2,RPL27,SEPTIN6,TRIM3,IRF3,PML,NBN,PGK1,GFM1,DLAT,HPS6,GTF2H4,CDC42,CD2AP,SNX2,BUD31,ERLIN1,CACYBP,WDR6,THOC2,PPP2CB,COPS2,DDX23,UBE2D1,HBA1,TRAF6,PPP3CA,RPL23,PRPF19,CLPX,SAV1,CREBL2,FIG4,EIF3D,TRA2A,TRIM26,RBBP7,MCM6,SRSF4,MRPS17,RFC2,HS2ST1,AKT2,MORC2,ZC3H7A,VPS26B,PPFIA2,OXNAD1,RBPJ,GNB1L,GTPBP1,TXNRD1,CYB5R1,GFPT1,MB21D2,RPL35,UMPS,DYNLL1,TSN,CHCHD3,GNB1,UBE2S,RAN,PELO,PIGK,BLVRA,LMNB1,CUL2,TOMM40,RNF40,MCM4,MCMBP,ZBTB39,THOC3,HADHA,COMMD2,ATP5PO,APOBEC3C,RTF2,PRKAB1,WDR77,PRDX3,PPP1CB,IDH3B,EIF2B2,AKAP17A,ETV6,HACD3,SRPRA,SRP14,LRRC4B,CRBN,PSMD7,EXOC2,BPIFA3,CALR,ORC5,GMPPA,TLE1,LRRC40,MFN1,CTNNBL1,BACH1,THRAP3,TOM1,PDE2A,RPS13,ARF4,MSH6,PRDX4,NSDHL,DLG1,PC,AGA,SLC6A3,UBE2B,PPP4C,APEH,MTA3,IRGQ,TBK1,NECAP2,DDX39A,EEF1A1,ALG11,LBR,BCS1L,RPL15,RAB14,LDHA,ZNF622,ARMC6,SLC25A4,SNX3,YES1,DYNLT3,RPL22,STUB1,QNG1,HYCC1,OPTN,EIF4A3,CAB39,DTYMK,GANAB,UBASH3B,PTEN,RPS20,CHORDC1,PIP4K2C,CA2,CDC16,DEPDC1B,KPNA6,PPP1CC,PFKFB2,RPL4,FBXO9,PRPF4,SYVN1,ARPC2,JUP,MRPS34,LMNA,OXSR1,ZNF574,EPHX1,RPLP0,KCNH1,RBFOX2,RPS14,PSMC4,CCND1,EEF1E1,PRMT2,ELP3,CNP,PAIP1,DYNC1I2,VAMP7,MACROD1,PGS1,SRSF1,HOMER3,MAGED2,DIPK2A,DRG1,HSPB1,CFAP61,CIAO3,PPFIBP1,PPIB,NT5C2,H1-6,CCT8,TOP2B,PICK1,DNAJB4,ACTR1B,RTCB,NUDT19,KDELR1,ZRANB2,GNAZ,RPL18,AAMP,CRKL,SUPT5H,RANBP1,TRAF2,CBLN4,ATP5F1B,SNRNP40,GDPGP1,PPP5C,RORB,DES,SF3B4,H1-10,FTSJ3,PRSS1,MCAT,GFUS,THAP7,PCCB,EMC1,PRCP,OXCT1,RER1,MRPS7,SNRPA,DDIT3,EP300,CTBP1,PALS2,ADSS2,PLAA,GAMT,FDFT1,SHMT1,PAFAH1B1,RALYL,NEK7,MIOS,IFRD2,RPS16,PNMA3,TMPO,DKC1,GLT8D1,COQ8A,STT3A,RNF128,TRAPPC3,LANCL2,RPS2,CDK12,USP15,KARS1,RBM17,PGAM1,COPS5,KDM4B,CDC40,SRPRB,TMEM33,FKRP,CAPZA1,FKBP8,PALM2AKAP2,TCEA2,SLC25A11,ERO1A,MRPS18B,TRAFD1,TFRC,GFM2,TBC1D4,NAA35,RRM1,SRFBP1,UBL4A,RAP1A,MRPL47,MTCH2,RPAP2,MRPS21,BUB3,KCTD9,CEP41,GABPA,PPAT,PRKCE,MYG1,SMURF1,SUCLG2,BCCIP,SRPK2,RPS3,ACOX1,LIG3,ABHD14B,PSMC5,MRPS28,MOB4,GTF2H2,RAP2C,DNAJC10,CALU,C9orf72,EXOC5,RPS17,CHPF,RBM22,EIF4E,MARS1,UGDH,HNRNPH2,LCP1,TCP11L1,RPRD1B,RPA2,EIF2B3,GSTP1,ACACA,CAPN1,SETD3,NEK2,TRAM1,CREBZF |
| 3.125e-38 | -86.36 | ZC3H18 (zinc finger CCCH-type containing 18) | protein interactions | 124245 | 868 | 419 | 19454 | 5460 |
NME2,MOV10,NCBP2,CWC15,MRPS23,RPL35A,THOC1,RPL12,KRR1,TOPORS,LLPH,CD2BP2,EXOSC8,JPH4,TSSC4,NSMCE3,FARSA,RPL23A,TCOF1,NKRF,SFXN1,PQBP1,CDC73,PPIG,SDF2L1,RPL26,VIRMA,DEK,COPE,RPP25L,RPS12,ENO1,EIF2AK2,POP7,RARS1,HNRNPH3,RPL26L1,WTAP,CCNA2,SF3A1,TXNL4A,PIP5K1A,LSM8,BRIX1,FBXW7,CLK1,PPIH,SOD1,RPA3,HNRNPD,MRPS26,MPHOSPH6,SKIC8,WDR12,HNRNPA1,ZNF207,HMGA1,SRSF10,PPIA,DHX15,RPLP2,RPL8,RPL9,MRTO4,RPS11,SNRPE,RPN1,EXOSC3,PPP2R1A,RPL29,CSNK1E,RPS27A,SSRP1,SRSF7,HSPD1,SLC25A5,HNRNPA2B1,HSP90AA1,RPS5,LSM14B,FYTTD1,YWHAZ,PRPF31,RPS29,PYCR1,PRRC2A,ERH,PRDX2,MRPL23,RPF1,TUBB,SNRPD2,SNRPD1,RPS9,SEC61B,ZMAT2,RSRC1,MFAP1,SLC25A3,USP39,ACTL6A,AZGP1,NOP53,EMG1,C1D,LSM3,AKAP8L,MAP4,RPL24,ELOC,GAPDH,ENY2,FZR1,MIF,RPS27L,RPL32,ALYREF,NUPR1,TP53,RPSA,RPL17,MRPS33,SCML1,HNRNPK,DHX9,IGF2BP1,EXOSC1,UBE2H,RBM7,MRPS16,CFL1,SLC25A1,SMARCA5,RPL7A,CSNK2B,FGFBP1,CALML5,RBMX2,MACROH2A1,SF3B6,PSPC1,TMA7,DYRK2,TFIP11,LUC7L3,SSR1,CDC42,RPS15,WDR3,NME4,RPL27,DDX46,MAGOH,NGDN,DDX50,RPL6,HSP90AB1,CCT7,ISG20L2,RPS10,HNRNPL,SNRPA1,SNRPD3,FUBP3,RPS23,H1-3,NCSTN,EEF2,RPS7,CBLL1,HNRNPF,RUVBL1,EWSR1,RPL31,LSM14A,RPS26,RCL1,CKB,CIRBP,FBXW11,SNRPB,MYC,SFN,HNRNPAB,LDHB,HNRNPC,RPL10,ESR2,MATR3,SMU1,NUFIP2,CSNK1A1,MRPL12,ZC3H14,FXR2,TRA2B,SRSF2,PHB2,SF3B1,DDX5,ZMYND11,APOBEC3F,AKAP17A,ZBTB2,TOP1,PWP2,AIFM1,SRP14,H2AZ1,HACD3,GEMIN7,ILF2,SRP72,EEF1A1,LBR,RPL15,MRPL11,RPS13,SNRPG,CTNNBL1,CAMK2G,PAK1IP1,LSM4,HSPE1,THRAP3,ZC3H11A,ATP5F1A,PPP1CC,TUFM,NONO,PYCR2,TECR,RPL22,LDHA,MAGOHB,RPL13A,RTRAF,PRKRA,RPS20,TRIM24,EIF4A3,RPLP0,NOL7,MACROH2A2,LMNA,CDK1,H2AC7,HSP90B1,LSM2,CPSF4,WDR83,RPS14,SAP30BP,EEF1E1,NHP2,MBD3,GTF2I,NPM3,RPL4,HMGB1,MTDH,SIRT7,PRPF4,PNO1,RPL23,DDX23,TRA2A,EIF3D,PRDX1,PRPF19,NOP58,RPL7,BUD31,RPLP1,HP1BP3,THOC2,PHB1,MYEF2,SF3B5,EZH2,LGR4,SRSF4,MRPS17,RBBP7,G3BP1,RPS24,SRSF8,NDUFA4,ARGLU1,PPAN,SP1,LMNB1,RNF40,RBM15B,CUL3,NOP16,CFAP20,RPL19,SNRPB2,RPL35,RPL7L1,DYNLL1,RBBP4,AP2M1,RPL37A,CPSF1,FAU,RAN,UBE2S,ATP5PO,TIMM13,PRDX3,H2BW1,COIL,SKP1,CCDC86,THOC3,CDK12,RPS2,RPL10A,SNRNP70,CSNK2A1,KARS1,CMSS1,RBM17,DKC1,RBM42,TMPO,CDC5L,SURF6,RPS16,NKAP,SYNCRIP,IK,RBM34,WBP11,H2AX,SRFBP1,SRSF12,CAMKV,CDC40,KPNA2,RPL3,SLC16A1,SNIP1,SLC25A11,ELAVL2,EIF3G,LSM6,RPS17,UTS2,RPF2,SUB1,SRPK2,BUB3,EIF2S2,RPS3,ZNF330,ACACA,RPA2,ZNF326,SNRNP27,SPTBN1,TOMM20,MARS1,HSPA5,MRPL41,RBM22,EXOSC4,TWNK,RNF113A,HSPB1,PPIB,PAIP1,EIF2S1,MEAF6,FAM98A,LSM5,LYAR,CLK4,FABP5,POLR2L,SRSF1,ZRANB2,RPL18,NFKBIL1,SMNDC1,UBL5,PPIL3,RANBP1,SUPT5H,RPL28,POLDIP3,KRAS,VDAC1,RUVBL2,RTCB,CCT8,RBM3,THOC6,NSA2,FTSJ3,RBM27,CHTOP,H1-10,RPL39,ATP5F1B,SNRNP40,SF3B4,NCOA5,PABPC5,RPL27A,SAP18,HNRNPA0,STAU1,HSPA8,SNRPA,RFC4,XRCC5 |
| 3.268e-38 | -86.31 | protein-containing complex | cellular component | GO:0032991 | 6542 | 2288 | 19108 | 5553 |
RPL10,TOLLIP,RPS23,ELK3,MIR569,TNNT2,SRPRA,MIR618,KCNA2,MIR876,SNAP29,PPP2CB,SYNE4,RPL18,SHLD1,CREBZF,CENPW,MORF4L1,NAPG,CSTA,MIR296,PIH1D1,CDH11,ANKRA2,RORB,RPL24,MEAF6,SLC11A2,HOXC4,NBN,MPHOSPH10,BCL2L1,TOMM20,AGO1,MIR149,LIN7C,S100A10,RASGRP3,BCL7C,RRAGA,NDUFB4,CDKN1A,ZFAND2B,P3H1,TFCP2,MIR601,TAF9,GTF2B,GSK3A,STX6,GRAP,EEF1AKMT3,SMARCA5,BMPR2,BCL9,MRPS16,PPP2R5A,H2AC4,EMILIN1,ATP6V0B,NFYB,C1QL2,RHCE,CCNI,GTPBP1,PHF21A,NDE1,ITGAV,PSMC5,SLC2A1,CDC73,TERT,COPE,ATG101,PPP1R10,GABPA,SNRNP70,PELO,UBE2V1,MIR586,POLE3,KCNIP3,CD4,IFT22,ERLIN2,PRR5L,RPL12,TRAPPC14,ATP6V1A,CDK8,H1-10,SLC38A9,AKT1,LIG3,CRB3,ATP6V1E2,VPS72,COPS2,MIR342,DCAF5,ACTR1A,TLR4,PARD6A,SCML2,TRIM54,NDN,SNAP25,ASB1,SS18,COX7B2,ZCRB1,FKBP1B,RPL31,BRCA1,DLG4,DAG1,CD14,FOXJ3,NSMCE3,PRKCA,OSTM1,ADD2,F11R,ZCCHC17,DCUN1D3,DROSHA,SOX2,DLG1,MIR581,CHRNA7,WASF3,PCGF6,CAMLG,H2AZ2,CHMP1A,H1-6,MIR99B,H1-3,GLRA1,MIS12,CREBBP,FBXL3,MIR339,PRM1,MRPL10,TRIM37,SSBP3,MIR940,CENPL,ALYREF,WDR77,COX6B1,RPL27A,DNAL1,RPS12,EXOSC4,MIR9-1,KCNF1,SLC6A6,ORC6,SMAD5,VPS28,RPS24,MIR573,HP1BP3,CRTAP,RPAP2,CSTF2T,PSMB7,CDK2AP2,MIR1227,CAPN1,SUV39H1,MIR625,MTA2,SATB1,TNFRSF1B,LAMB2,MIR197,NFKBIA,RRAGB,KIF1C,MIR377,COPS7B,KDM1A,HADHA,DFFA,RARS1,POLB,MIR367,STRADB,GNAI3,ERLIN1,SIN3A,CXCR4,WDR19,NKX3-2,AP2A1,DRGX,RNASEK,CHRAC1,IL2RA,HNRNPF,BOLA2B,GTF2A2,PDE4B,STX11,MRPL50,BTF3,SCN3B,ANAPC4,ANAPC2,METTL21A,KCNH1,PAAF1,HDAC3,RPS10,GPAA1,RFC5,NDUFA4,IL6ST,GMNN,RCL1,SLITRK5,MIRLET7B,MIR23B,STAT2,SEC13,MIR205,METTL22,MIR632,UBA3,PFDN4,WDR12,TMEM107,JAK2,MIR873,NSA2,SSPN,STX17,PPP5C,ZC4H2,EXOSC8,DDX23,LDHA,NDC80,PSMD7,SDF2L1,KDM4B,XBP1,TICAM1,MAD2L1,ATP6V1G1,SEC23A,HM13,XPO1,LRWD1,RBBP8,TEF,MIR9-3,PSMD12,FOXA3,DCUN1D5,CTNNA2,IGFBP3,MIR16-2,STX12,NFIL3,STN1,SLC41A1,SRSF1,OTX2,CLDN1,INTS12,TRAPPC3L,GRM1,CHCHD3,ATP2B4,ATP5IF1,MIR504,FIS1,CRKL,PRKCB,SEC61A2,STAT6,HNRNPK,NTRK2,DYNC1I1,ARFGEF1,MRPL24,SNRPD3,BRAP,CRADD,VIRMA,ENO1,TGIF2LX,ZNF174,FAU,RFXAP,KCTD12,TOMM7,ATP5F1B,SMDT1,SDHB,ENC1,MIR345,STK4,HSP90B1,RPL10A,LSM6,PPP3CA,PSMA5,NOL7,SF3A1,TMEM183A,KCTD10,ABHD6,STX7,SNRNP40,TRPC1,GH1,CCNY,PSEN1,MIR30A,MIR552,IFT52,SLC25A4,SOST,CCNQ,MIR107,PNO1,ETF1,VCPKMT,EIF2B2,CDC5L,NOB1,IGF1R,SSX2IP,MACROH2A2,OS9,VRTN,GRIA2,B4GALT1,CLSTN3,MIR212,TRAPPC6A,MIR105-2,HGS,LHX2,ACVR1,MIR218-2,NFE2L1,ANAPC16,NUP42,EAF2,KICS2,KCNIP2,KIF2A,IGF2BP1,ZNF740,TOP2B,MIR500A,INSIG2,RBM12,DNAJC19,CKS1B,BCKDK,C1QL1,MAP4,TRAF2,ATP5PB,BAG2,EZH1,NSFL1C,MIR615,MARS1,COX7A1,IVNS1ABP,MIR484,H2BC12,MIR330,PTPN1,CACNB3,PCGF3,MRPL13,EEF2KMT,DHX16,FKBP8,RPS16,SNX5,NUPR1,CPLX2,FOXP2,SH3GLB1,SEC22B,IL2RG,RAD1,SAP18,CIAO3,MIR611,INHA,CSNK1E,PABPC1L,SUGP1,PSMA3,DISC1,PIGA,USP3,ATP5PD,NPPC,NHERF1,OTUD6B,POLR3F,NUP107,MIDEAS,OTULIN,MRPS21,NAE1,HELT,RAP1A,ARMC8,ESS2,PRKAB1,AKAP14,EIF3J,IDH3A,GABRA2,FANCG,HSD17B8,CBFB,UBE2B,VDAC2,MIR31,MRPL22,CYB5R3,EIF4B,BLOC1S3,CEBPE,RNF20,MIR143,BORCS8,VTI1B,ACTL6A,SKA3,POU1F1,RNF144B,MECP2,WRAP53,CLU,HNRNPA2B1,ACTN4,DNTT,IRF4,MCM4,MIR874,SNIP1,TMEM115,RPL7A,HEY2,ZBTB5,CTTN,DR1,H2AB1,ORMDL3,POLR2C,SF3B5,ALCAM,ELAVL4,STK3,DSN1,NDUFB8,RPS3,AP5M1,BIRC5,KCNK13,DIS3L,JUP,MRPL17,VPS54,UBA52,HAND2,COX11,AP1G2,PSMB3,SUPT4H1,TRMT6,KLRD1,DYNLL1,ADRB2,MPC1,OLFM2,NLGN1,DCTN4,CFDP1,MIR331,MIR101-2,ZMAT2,MIR216A,TTC8,NDUFA12,NFE2,NUF2,CD40,DDX5,EIF3K,TSHR,MIR221,ERCC3,ACTR1B,CPLX1,RPP21,KIT,MIR448,TRAPPC2L,PPP1R3C,MIR636,SNAI2,CTNNBIP1,GTF2E2,ZMAT5,CASTOR2,MIR136,ITGB8,SIAH1,POU3F4,SOCS4,RPL7L1,CLDN3,UFD1,VPS18,CDK5RAP3,CSF2,TIA1,NR2E1,NDUFB10,TMEM147,CDK5,MAGOH,TPM3,POLR3GL,FEN1,NUCKS1,RBBP4,MIR628,GRSF1,CIAO1,KHDC4,KLHL12,IL12B,HMX2,ATP8A1,UBXN10,KCNJ11,DICER1,ATG16L1,PCSK9,MSX1,HEXA,GID8,GNG7,PARP11,TOMM40,MIR624,AR,H2AX,ADIPOQ,SPATS2L,EXOSC1,MRPS9,CD2AP,DCTN6,GJA1,POLA2,TRAPPC10,HMGN4,ZBTB17,ZNHIT3,MIR934,PSMA6,CSNK2A1,CAV1,ANAPC13,VEZT,ATP6V0E1,CDC42,MAPKAPK5,MAP1S,TMEM199,SART3,PTGES3,KCNQ5,EIF1AX,MIR423,NOP58,MIR16-1,H2BW1,NCK1,TNFAIP1,BBS5,ATP5PO,BET1,ZBED3,CD34,UQCR11,MIR190A,OIP5,MIR324,CDC16,POLR2G,GCLC,KIF3C,MRPL52,ABHD12,ROMO1,NHEJ1,STK11,CPLX3,PRKACB,DAD1,TOMM6,TLR6,APOBEC3F,TAS1R2,MIR23A,SPOPL,VPS4B,NACC2,GJB2,SMAD4,FBXO25,TF,MX2,PDRG1,BLOC1S5,INTS6L,COX4I2,SNRPB,MIR125A,SNAI3,SNX3,MED9,CDC40,PPIF,CORO1C,PPIB,MAFG,BACH1,RIOX2,PCBP4,LARGE1,TSN,BICD2,IRF6,MIR190B,FTH1,SP1,MIR200C,PSMG3,HBB,PEA15,PAX6,MIR129-1,PEX3,SLC25A31,HNRNPH3,WWP1,BCS1L,POLR2L,NDUFB6,RPL7,SRP54,MIR626,MRPL23,DGCR8,PAXX,KLHL25,RBM15B,MIR26B,TRAPPC4,RAG1,VDAC1,PPP2R3A,PIGY,HTR2A,KLRC2,B9D1,KCNB1,UFL1,MIR455,CYB5B,TAF11,ERH,KLHL24,RUNX1,APOC4,INSM2,IL23A,IDH3B,TSEN54,EED,PSMB10,ATP1A3,GABRB2,ACTL6B,NGDN,UBE2A,KCNAB1,DDX46,MIR181C,MIR10A,MLH3,MIR9-2,MRPS35,ELF1,NR1H2,FAS,DYNLRB2,GTF2H4,IL6,RPLP0,MIR302B,MIR130A,RMND5B,PPAN,CALR,SMARCB1,RFC3,MIR338,MIR155,ATF4,APPBP2,CUL3,BABAM1,MKLN1,CFTR,GRB10,MAX,PSMG4,ATP5F1D,NOP53,APOO,SYNRG,MRPS34,MIR196B,NOTCH2,ING5,WWP2,MIR10B,KLHL22,EMC9,EMX1,OGDHL,MIR944,BHLHA9,CSNK1A1,MIR607,NRP1,PSMA1,GNAZ,CTU1,SNRPB2,PCGF2,MIR183,TAPBPL,RSPH1,DIPK2A,PPIA,PIK3R1,RTRAF,CD247,PSMD3,MRPL20,BUD31,SMAD3,NLRP6,S100A8,TAB1,METTL18,KCNJ8,TENT2,UBP1,SMN1,AP1M1,VLDLR,C9orf72,PRPSAP1,MIR198,TADA1,CAPZA1,GTF2F2,SESN3,NLRP1,MIR631,RPS28,BRMS1,RPL6,ZFAND2A,UTP6,TSG101,CD200R1,PPP2R5E,H2BC1,KLF12,RFX4,FLOT1,FBXO32,BRD3,BATF,HNRNPH2,FAM98A,GNA11,NUP37,B9D2,COX8A,ZMPSTE24,PSMB5,MRPL9,COPZ2,SOX9,GOLGA7,MIRLET7C,ZNHIT1,PRKRA,H2BC14,COX6A2,DUSP22,CDK4,MIR592,RPLP2,FGFR1,COG1,DDX42,NEO1,SKA1,NHP2,RANBP1,MYL6,POLD2,ZSCAN1,GPR37,EIF2S2,CSTF3,TOX4,MIR148A,GP9,CDH7,SNRNP27,FEM1B,GJA10,HSPA8,KLF1,TGIF2,TNNI1,NFKB1,GRPEL2,SPHK2,PSMB9,MRPL41,CSNK2B,HPF1,WDR3,TOMM22,WDR5B,HNRNPC,TAL2,CLIC2,MIR604,SMARCD3,FAF1,ATP6AP2,RPL26L1,PELP1,HMX1,CAPZA2,MIR761,GNAO1,MIR503,KCNJ10,CIRBP,TMOD1,MIR598,HINT1,CBLL1,PAIP1,PRELID1,ORC5,SYNCRIP,SMG5,CHCHD1,GEMIN7,SHPRH,EXOC2,ATP1B1,EEF1E1,GLRB,LBX1,MEF2B,NDUFAB1,GPD2,CDKN1B,TRAPPC3,PPP1CB,PICALM,STX18,MIR147B,MIR551B,ATP1A2,WDR83OS,DCAF4,BAZ1B,CYC1,ZBED4,NDUFV2,CCT7,UPK1A,QTRT2,COX5A,TOPORS,GPIHBP1,GINS4,PRKAG1,LMO4,SF3B6,GHR,NCSTN,CCT5,FKBP4,KCNMB1,MRPL18,BAHD1,EXOC3,MIR605,PPIL3,SNRPD1,MAGOHB,NAP1L3,KCNJ3,ARCN1,RNF11,TRMT10B,EXOC5,ADNP,SP4,MSL2,IFT57,IMP3,CDK12,MIR150,ACTR2,RNF40,KCND3,MIR661,PHKA1,MRPS28,MIR29A,ACVR1B,MIR612,MRPS25,MIR578,NEUROG2,LUM,TRIM21,MIR132,NR1I2,MZT2B,MED21,MIR96,GPBAR1,TCEA2,HDAC6,SCLT1,KPNA2,MIR142,CAV2,CPSF1,NUP35,GINS3,NAA16,MIR30E,COPS4,TRMT112,IKBKB,ITGA2,MTA3,VAMP2,MIR24-2,SUPT3H,NCR3LG1,SNAPC1,TOMM40L,ZHX3,MIR450B,RPL19,VDR,SOCS5,CD36,LHB,LSM3,TSPYL4,MIR887,SNRNP48,ATP5MC1,PSME1,ELP6,MIR126,SPCS1,LUC7L3,PIAS1,TRAPPC6B,NDUFS8,FOXS1,ZNHIT6,SERPINB6,UTP15,PRPS1,MAK16,DCAF11,THRAP3,STUB1,MIR361,DHX15,RAMAC,CELF6,RPS27L,SNX2,WTAP,FBXW4,DRAP1,RP9,BRMS1L,RB1,INO80E,SLX1A,FHIP1B,FBXL7,MIR24-1,CDK7,GABARAP,SAP30L,CHCHD6,RPS13,GRPEL1,EPOP,PHAX,MIR155HG,PCMTD1,RB1CC1,LGALS3,NDUFA1,GNG3,THOC2,MIR675,SNRPG,MIR152,STX5,ACVR1C,LEPR,DYRK2,HSPD1,AKAP17A,RAMP3,STX10,PCNA,KCNMA1,HNRNPA1,MIR7-1,UQCRC1,AMIGO1,MIR577,LSM10,LY96,ATP5MK,GNG2,DMAP1,MRPS18A,MIR17,MIR222,NKX3-1,SNX17,BUB3,OGG1,PFDN1,GNAI2,RPL8,LRRC8B,DRD1,PLCB1,ELK1,NOC4L,IRF2,MCM6,H2AC25,MRPL16,NCALD,FEM1A,CENPP,SEC63,TCF23,MIR29C,CTNND1,CCM2,TFIP11,MFAP1,EMC4,GNG10,RPL26,SSRP1,RBCK1,DESI1,MIR491,CRYAB,COX4I1,TNKS,MIR218-1,IRF8,SPECC1L,ATP1B3,MIR106B,VPS16,IZUMO1,SLC6A3,FCER1G,MIR542,PDCD10,RPL10L,CETN2,POP7,HSD17B10,NCKIPSD,ATF3,RAD21,JUN,SSU72,TENT4A,CETN3,MIR346,TLR7,LAMTOR2,MCM8,COPS5,ESR2,RPP14,MFN1,SRSF2,APOBEC3G,NAT9,KCNK17,DDX1,EIF4E3,APTX,MIR146A,HNRNPD,NTRK3,MIR375,GTF2H2,AFTPH,SHOC2,TRNP1,RPS2,GUCY1B1,ZNF622,MIR140,RPL4,VIPR1,RAD23B,TOP1,CFAP91,HDAC5,KBTBD6,METTL14,ALB,NDUFB5,COL1A2,CTNNA1,IKZF5,EIF2B5,NEUROD6,RS1,TSNAX,GNB4,CLEC12B,EMX2,TMED3,GTF3C4,TIMM10,PTPN11,ANAPC11,CWC15,NECAP1,ZSWIM7,SPOP,SPSB1,RIGI,PPP3R2,MIR7-2,TRAPPC13,PSMB6,PYM1,PHF1,SLC1A2,SMAD1,DPY30,TUSC3,MIR153-1,TAF10,ETFB,CCT8,EMC8,MIOS,AZI2,GABRB3,OLFM3,BMPR1A,RPS27A,MIR185,PPP1R12A,CLPX,MYH2,LSM5,NFYA,PGR,ATF1,OST4,SAMM50,MED17,BAP1,HFE,PIWIL2,SNRPE,EPHA2,GABBR1,FXN,PRPF19,MRPS26,STX16,JPH4,WDR83,MIR133B,FBXO42,RLIM,ZBTB16,CHMP1B,SPTAN1,OLR1,EIF1B,B2M,ELOC,PIGC,FLCN,ATP5PF,RPP25L,PHKG1,SEPTIN7,SYVN1,PROX1,KGD4,MIR490,MREG,RUVBL2,H2BC11,MIRLET7D,RANBP10,VAC14,MBL2,MYO1B,MXD1,MIR452,VIPAS39,NECAP2,FKBP1A,RPL32,AP3S2,PSENEN,ING2,POLE4,CDC26,MIR129-2,AKAP8L,MYO6,CTNNBL1,LIN7B,RPS11,HSP90AA1,BRD9,CLBA1,TRAPPC1,KCNG3,SOCS2,GON7,MSX2,MIR589,QRSL1,RFC4,FOXN2,GNG5,BOLA1,LY6G6C,PRPF31,DNTTIP1,RNF7,DBT,CTSB,KCTD17,ESAM,TBC1D5,COP1,PDIA6,FBXL14,MRPL49,XPOT,MITF,KCNK10,SF3B4,ACTA2,H2AC6,MIR195,COX10,CAPG,CBL,CCND1,FNTB,MIR942,KXD1,POLR2I,C1D,MRPL12,SETD3,EFCAB7,BCL7B,ENY2,AP2S1,RCHY1,POLR2D,CREB3,KLF9,HCLS1,CBX5,RAN,PIK3R3,MIR424,BANF1,TRA2B,BCCIP,GNGT2,SUPT5H,CNOT6,FARSA,LDB1,MIR191,CWF19L1,DNAL4,SYK,SFTPD,MIR495,MIR15A,NAPA,MIR1251,CNOT7,ETFA,PHKB,TXNL4A,BAX,UGT1A1,MYL12B,ELK4,MIR489,ATP6V1D,MCM3,HSPB8,SNRPA,UBE2V2,HAUS2,MIR556,NUP153,RHAG,PKNOX1,MAT2A,NDUFS2,GLRX5,MAP1B,ATP1A1,RBM22,CACNB2,HRAS,ITGA6,HOXB1,PRDM4,EMG1,TIMM23,RPS5,KLK3,CHMP2B,STX8,GPR89A,HBP1,MIR98,PDHB,ANKIB1,INTS10,GANAB,NXT2,KCNH8,NUS1,LAMTOR1,KCNMB2,IL12A,MIR938,PEX13,RPS17,PADI2,MIR30D,ARF1,GNB1,FCF1,MIR593,APH1A,THG1L,PDSS2,HBE1,IFT25,AGK,MIR141,CDK9,HTRA2,STX1A,UBE2N,YPEL5,CD80,FBXO31,SNTA1,ZNF326,MCOLN1,EP300,SF3B1,CHMP2A,SUMO1,MIR25,PSMC4,MIR653,STAP1,CNOT2,SERPINA5,HNRNPL,DYNC1I2,PHB1,SDHC,TSEN34,CAMK2G,BORCS7,NDUFS6,H2AJ,RNF113A,KCND2,CARHSP1,EEF1B2,FTL,SLU7,CD2BP2,FBXW7,DDX39B,CD79B,DDIT3,CD2,UBXN6,CD9,ADD1,MIR1-1,CPEB1,MRPL53,CNNM4,PDLIM3,PPP4C,MIR147A,MIR21,ZBTB33,RPL28,NR2F6,CNOT8,CAPN2,CASC3,LAMTOR3,BET1L,GRIA1,MRPS17,PSMG2,HDAC11,DCTN3,MRPS7,TNR,NEUROD2,TANK,RERE,RPRD1B,GTF2A1,PAX9,FEM1C,H1-1,TOMM70,RMI2,NAA11,PTPRQ,GOSR2,VEGFA,FOXD3,MYL12A,ARL6,SFTPA1,TFPT,EEF2,RMI1,MEF2A,SARM1,HCFC2,TUBG1,FBXO44,MIR920,CCDC65,HNRNPDL,SGIP1,SUB1,UBE2S,TMPO,RGP1,KPNA6,C1QL3,RPS7,FBXL4,TES,SHC1,H2AZ1,AIP,BLOC1S2,PAGR1,EMC10,BCAS4,TADA3,DLST,BMPR1B,SPTBN1,NDUFA5,RPL35A,DYRK1A,UBL4A,TLR2,AP1S2,RPF1,LDLR,RBM5,PSMD14,SOX21,KCTD16,IL2RB,MRPS33,RPRD1A,MRTO4,RBM41,LY6G5C,UQCRH,DNAAF10,TTI2,CLDN4,MRPL11,MIR643,MED10,RBMS2,ROGDI,MET,PPARG,PSMC1,BHLHE40,CHP1,RPP25,H1-5,TIMM29,MIR33B,GFI1,DLAT,UBE2D1,MIR214,SLC51A,YKT6,RPL29,LMO2,MIRLET7I,CDC20,WDR82,CBX7,NABP1,VAMP1,MIR223,CCNA2,ELF5,PRIM2,SRP72,CREBL2,USE1,PFDN6,GNA14,TIMM13,MDM2,HSPB1,MTPN,HP,AURKAIP1,KCNA3,GCFC2,EIF4EBP3,NR0B1,SRPRB,RPL23,UQCC3,RPAP3,POLR1B,BORCS6,CCNF,MIR30B,MIR551A,RBPJ,TFE3,MED22,PSMB2,HR,SMU1,DEK,GOLGA7B,DHRS7B,EIF2D,PDLIM4,H2BC9,HSPA5,RTCB,FOSL2,LBH,DCAF16,KLHL9,ATP6V1G2,XRCC5,SDCBP,TRAF1,EZH2,FOXP4,JAKMIP1,HSP90AB1,CEP97,GTF2H5,COX6C,CAND1,TLE1,DCAF4L2,SLC25A5,EIF4A2,MIR145,GTF2E1,ELOVL6,TAF1D,NRBF2,TFEB,ACTB,ASF1A,DAPK1,PPP1R8,BAK1,RPL22,MIR671,ATP5MC3,GABRA1,MIR320A,IRF9,MATN4,CDK6,GOSR1,TMEM30A,PRPF18,PLCB2,MIR657,MYD88,FERD3L,SLC22A6,H2AC1,RPL13A,LCP2,MRPS23,MIR370,MORC2,HPS6,PHF12,MAEA,KPNA1,SOX3,PSMA4,NOP9,STXBP1,ZHX1,ETFBKMT,MACROH2A1,ZBED1,LDHAL6B,SPCS2,SKP1,MIR148B,MYC,MIR936,MED31,RACGAP1,SCN2B,SEPTIN6,SMC4,MIR609,CCDC47,DCUN1D1,POP5,THAP7,G3BP2,LSM14A,CISH,UPF3B,DCAF12L2,MEPCE,PMAIP1,PFDN2,MRPL51,ETV6,DCLRE1C,SIX5,MAT2B,MIR711,STAT1,KIF3B,EXT1,FBXO11,TBK1,ORMDL1,WBP2,API5,PLN,VAMP8,RPS14,DCAF8L2,GNAQ,MED27,MCMBP,SNRPD2,UBE2D3,ZBTB18,FBXO8,CFAP61,CDH8,RING1,SUFU,ZER1,TMEM231,SGF29,TESPA1,APOC2,MTX2,MED23,PIK3CG,RPA2,RNF14,CAV3,FOXP3,DLG3,CHRNB2,SOD1,VPS33A,MPV17L2,MIR335,IRF1,SECISBP2L,NUP62,RPL35,IMP4,PRPF4,CD28,TIMM8A,MYT1L,RBMX2,MIR922,RHEB,FOXC2,RNF8,JCHAIN,MIR206,KRT8,SNRPN,MRPL40,DNAJC10,MED4,MED29,MIR153-2,FAAP100,CACYBP,RPS9,IMMP2L,MIR7-3,BECN1,EMC2,MIR101-1,GLRA2,PABPC5,TAF2,PFDN5,BORCS5,MXI1,CYFIP2,COL3A1,MED30,MSH6,VAMP3,SAP30,MIR764,KLHL3,TLR1,SMARCE1,KLC2,MRPS11,ENO2,MIR210,ACTL9,CLIC4,SPSB3,SEC61B,THOC3,CASP12,CATSPERZ,SPTSSA,EXOC8,ANAPC15,POLR3H,RPL17,PIK3R2,LSM8,TCEA1,MIR502,TXNL1,STAC3,AP5S1,CTLA4,CHMP5,XPO5,SAR1B,KLF3,MIR590,PSMD10,PGGT1B,THOC1,SLC7A1,EIF4A3,ATG3,C1QTNF1,MNAT1,DCP2,EXOC1,DKC1,CCND3,EIF3E,SOX14,SIRT7,GJC1,MIR194-2,CREB3L4,STAT5A,SESN2,NAA50,RPLP1,MIR648,DYNLT3,TFDP2,RNASEH2C,RABGGTB,UQCRQ,MIR194-1,PIGK,RPS29,EGR2,SNAPC3,TRIM24,PSMD6,FZR1,RFXANK,CDK1,HAX1,PPP2R1A,LSM14B,SKIC8,CNOT6L,RPA3,KRIT1,PSMB11,NDUFS3,CTBP1,GLE1,NR1I3,FBXL19,HMGB1,RPS15,KCNC1,CLP1,PRMT5,LRRC8C,KLF4,CDK5R1,ZC3H14,SKA2,SDR16C5,HELLS,MIR600,EIF4E,BARX2,PDHA1,BAD,TAF7,GNPTG,MIR192,MIR211,E2F6,NUP50,MIR572,RBBP7,UBE2I,MIR425,PPIH,EIF2S1,SCN1B,PEX5L,ROCK1,TCF21,PHC1,CD3G,PIP5K1A,MIR135B,TSSC4,MIR770,TMED7,SNX1,ELP3,SNX12,POLR1D,OSGEP,MIR1296,DHX9,UBAP1,GJB1,NR4A2,MIR580,CASP4,ASCC1,CENPM,ISCU,MIR99A,H3C1,SELENOS,WDR6,GEMIN8,DDR1,RPL15,RPS20,H2AC13,MIR505,MIR184,RRM1,LRRC8A,STAU1,HLF,DPM2,RPL23A,MED13L,TP53,SLA2,RAC2,KLHL7,MIR100,KLHL15,COPS7A,KCNJ2,TLR10,PAFAH1B3,HMGA1,TNNC2,VPS4A,CPSF4,ISX,EGR1,SPC24,VPS39,GPX4,LSM2,PCCB,CSRNP1,E2F4,IFT172,POLR2F,MIR454,AP2M1,MCL1,RINT1,UTP25,IRF7,LDB2,RPL9,SNAPIN,FBXO7,TRIP4,SRPK2,MIR204,CTNNB1,NCBP2,CCNH,CXXC1,SNAP23,SEC61A1,TIMM21,VPS26A,MYBL2,DHX38,PPARA,WNT2,BAG3,H2AC7,LSM4,RPSA,NKX6-2,MBD3,MIR1-2,UTP23,PSMB1,ATP6V1C1,NAA30,ATP5F1E,F7,GPR160,JADE1,RBM42,CCAR2,GNG12,SOCS3,PTN,NAA35,TAPBP,UQCRC2,MIR105-1,NEK2,CACNB4,FAF2,NAA15,JUNB,PPP1CC,HNF1B,HEXB,MRPL36,SUPT7L,SPTSSB,DLX1,EIF3D,SESTD1,MRPL47,RPL37A,NDUFA2,TRIM27,GNB3,MIR553,MPHOSPH6,NLRP3,HYAL2,ELOF1,TIMM17A,ELAVL2,UBE2L3,CCT2,DET1,LRP6,VPS26B,NTN4,HIRA,PSMC3,PPWD1,MIR877,MIR216B,RNF139,FCN2,MIR20A,SLC1A3,SMAD2,SCNM1,MYH1,TERC,KANSL3,SUCLG2,MAVS,MZB1,GNG13,CBR4,FAM8A1,RPS26,POLR1H,TRA2A,MEF2C,PYCARD,CDH13,BOLA3,CCNB1,MRPL34,SRP14,PAFAH1B2,COX7B,FOXP1,PPP2R2C,KIN,HOXD12,FBXO3,MIR139,KCNS1,PXMP2,CNTFR,NDUFC2,RPN1,PDIA3,TRAF6,DERL1,USP39,FGL2,GAPDH,TGFBR2,CREB1,MIR383,SEC61G,ADRM1,NDUFB7,DTL,IK,HBM,ZCCHC7,EIF2B3,SRFBP1,DPP10,MIR186,RPL27,G3BP1,TAF5L,EIF3G,RRP7A,ILF2,MRPS18B,TFRC,CSRNP3,THAP1,MAEL,ZC3H11A,CHMP4C,PSME2,TRAF7,HBA1,FBXO9,ITGB5,MIRLET7G,CNPPD1,SGTA,MIR558,RIOK2,MED11,LRRC8D,BCL10,EPS8,HOXB8,TCP1,TIMM8B,PABPC1,PLP1,NLRP9,CAB39,MIR497,GPR37L1,MIR215,EXOSC3,CEBPG,GTF2F1,MIR187,PIK3CA,EEF1A1,NFE2L2,KLF10,FBXW11,CHTOP,TUBB,RAB11A,RUVBL1,ELMO1,RBM3,IGF1,CDKN2D,RETREG3,ILDR1,TRMT61A,RPS4X,CPSF2,CACNG3,PSMD4,PSMD1,HYPK,MRPL33,STT3A,EMC6,PSMA2,UBE3A,SNRPA1,POLR3B,MAD2L2,ATP5F1A,EMC1,CDC23,RPL39,SEC11A,THBD,NONO,PRDX3,C1QC,CUL2,CIDEB,NXT1,MRPS18C,INO80C,LDHB,GID4,RFC2,GABRG2,MIR32,PWP2,HNRNPAB,AATF,KATNAL1,PHB2,ARPC3,MIR1180,CKS2,RPL3,PAFAH1B1,GTF3C3,VAMP7,MIR144,IRF3,ATP5MG,ARPC2,MIR106A,SETD5,BIRC2,POLR2B,ARMC7,NCAPG2,GNG11,MIR656,MIR200A,SPCS3,PMPCA,RXRG,FTSJ3,H2BC17,CRBN,SP2,TOP3B,ILVBL,USP14,EIF4H,POLD4,KARS1,PSMB4,MIR488,MIR640,CBX3,SMAD9,NCKAP1,PSEN2,MIR137,THOC6,RFX5,MIR939,NUDCD3,GRIK1,PLXNC1,TOPBP1,ADRB3,COX6B2,KRR1,GSTP1,HEXIM1,MIR1249,MRPL57,EIF4E2,FOS |
| 1.019e-37 | -85.18 | ELAVL1 (ELAV like RNA binding protein 1) | protein interactions | 1994 | 2018 | 819 | 19454 | 5460 |
SMNDC1,GNAZ,CRKL,RANBP1,NETO2,OAZ2,ISG15,TRAF2,KRAS,RWDD4,RERE,LEPROTL1,FBXO11,TMEM268,GPM6B,CNOT8,PPFIBP1,TMEM97,SRSF1,SDC4,LAPTM4A,SDC2,CTBP1,SETD9,ELK4,MRPS7,SLC18B1,FLYWCH2,SNRPA,HIRA,RAB5A,RAP2A,EP300,LAMTOR1,THOC6,SNRNP40,GDPGP1,DTD2,RAP1A,WBP11,SRPRB,CAPZA1,STRADB,UST,MRPS18B,VCF2,CDK12,RBM17,ORMDL3,ANKRD10,COPS5,HP,RPS16,ARMC1,CDR2L,STT3A,TRIM45,RPA2,ZNF770,SLC35F6,CREBZF,NEK2,SETD3,TRAM1,CRYL1,NAPG,EIF4E,UGDH,RAP2C,ELAVL2,UHMK1,MFSD14B,MORF4L1,C9orf72,SPRED1,PRKCE,BUB3,KCTD9,RASL11A,ZBTB33,RBPJ,GPBP1L1,TXNRD1,GFPT1,TRIM37,ZBTB14,ARGLU1,OSTM1,SRSF8,SLC25A23,INO80C,CDKN1B,MT1X,TRIM8,SAV1,TRA2A,CREBL2,POLR3F,SELENON,SERINC3,CGGBP1,CBFB,NEO1,PBDC1,MED23,APOBEC3C,RAB6A,TIMM13,LRTOMT,PPP1CB,LZTFL1,IL1B,TMEM127,SKP1,ZBTB39,COIL,EEIG2,PMAIP1,NMRAL1,LMNB1,SNX10,EXOC8,CUL2,GRB10,MCM4,GNB1,TNPO3,CHP1,RAN,VGLL4,LRRC1,FZD6,JOSD1,FBXO8,PPP4C,OSGIN2,TMEM101,MTA3,ING1,SOCS3,WASL,SLC25A32,ARF4,KATNAL1,SPSB1,SNAP23,HAPSTR1,TTPAL,CD9,ARL2BP,MED21,SSX2IP,CALR,ZMYND11,GTF2E1,ZBTB2,RCHY1,ETV6,C2CD2,FAM199X,LMNA,MRPS34,OXSR1,PDCL,CCND1,RBFOX2,SS18,MBD3,SAYSD1,PIP4K2C,IVNS1ABP,PNPO,CASC3,EPHA2,ZMYND19,KPNA6,PPP1CC,SNX3,MMD,YES1,F11R,SMAD5,VKORC1L1,QNG1,OPTN,UBASH3B,PTEN,GLTP,PLS3,CLDN12,SLC25A44,FOXJ3,NCSTN,TMEM59,FOXN2,ROCK2,FEM1C,RUVBL1,LTO1,LSM14A,BCL9,CDC23,PTDSS1,WWP2,SPATA2,DDRGK1,BTF3L4,CTNNB1,OLR1,YWHAG,SNRPD3,SUMO2,MITF,OSBP,HNRNPL,TRAM2,METTL25B,PRCC,RAB31,PCDH9,MAP2K1,FRS3,ZC3H14,AKIP1,MACIR,DDX39B,DDX5,PCGF2,DR1,PDSS2,MRPS25,TRIB1,COP1,HNRNPAB,CREBBP,SNRPB,IGIP,BTF3,MATR3,RNF141,EIF4E3,PPP1R3C,DLG4,MIDEAS,VEGFA,MIRLET7B,ZMYM2,RETREG3,GUCD1,CBX3,GNAI3,NUPR1,HNRNPK,SCML1,RPIA,SNRNP48,CHMP1B,SEPHS1,MEPCE,KLHL24,BCAP29,SMIM12,BCL10,CCDC92,USP3,TMEM19,PHYH,SPPL3,SLC38A2,LMAN1,ALYREF,UBE2N,CDK6,MTAP,SSR1,CDC42,HCST,RPS15,AIF1L,WDR55,TMEM263,GRAMD2B,CHRAC1,MRPS16,ALKBH5,UBE2H,FAM193B,SUGP1,NPTX1,ST13,PSPC1,TBCCD1,RBMX2,PITPNB,GDI2,AQP3,MTMR2,POLR2D,DLG3,CSNK1E,RAF1,LYPLA1,ERLIN2,PPP2R1A,OTUD6B,S100A10,TNF,UFM1,TMED7,HNRNPA2B1,HSPD1,MKLN1,SLC20A1,MED4,TMEM30A,VPS26A,PMP22,DNAJB9,WDR44,PPIA,ZNF664,ISOC1,LARP4B,FEM1A,PRSS23,SLC48A1,RNF182,CMTM6,FBXO30,ASB3,STX7,PYGB,NKAPD1,SPOCK1,SERTAD2,PSMA3,DCAF4,RHOB,VMP1,PFDN2,TMED4,SLC16A4,ACTB,LAMTOR3,TENT5C,LRRC8A,ERH,USP5,FCHSD2,MAT2B,ZMAT2,ACTR2,AP1S2,GBE1,CMPK1,FRMD8,EIF4EBP2,ABHD10,VTA1,SFXN1,PPP1R12A,RAB1A,LIPA,CCNY,TGIF2,IRF9,GRSF1,MOV10,ZNF200,ATP1B1,CDC42SE2,TP53INP1,TSC22D3,ANKRD46,PLEKHF2,ALDH1A3,LDLR,TES,STARD3NL,TRAK2,TCEAL8,METTL2A,HNRNPH3,DDAH1,ADIPOR1,CDK7,GABARAPL2,TMEM167B,SLC7A1,PEX26,CDC42EP4,RDH10,RPA3,MIRLET7I,SMAD2,CD164,CTNNBIP1,TRAF3IP2,PTHLH,TENT4A,CAMK2N1,CCNF,MSN,TLNRD1,CAAP1,GLE1,MTA2,PPIL3,TOP3B,ERRFI1,TNPO2,VDAC1,POLDIP3,HNRNPDL,CDCA7L,RBM3,PABPC1,SPTSSA,AGR2,ZDHHC14,YWHAB,TGFB3,POGK,UBE2E2,FAM20B,STK4,CBR4,MEAF6,GFOD1,EIF2S1,HMG20A,ELK1,CEP57L1,EED,CORO1C,ZHX1,FKBP14,PAK2,NCOA5,OSR2,SLC19A2,KLHL3,ZNF362,PITHD1,STAU1,EIF1B,UBE2D3,HNRNPA0,RNF41,RPP14,STK26,TIFA,CHTOP,S100PBP,RBM27,PAPOLA,TMEM38B,TTC33,NLGN2,ZNHIT6,EFHD2,PHF21A,PHC1,TAF2,SPRY1,H2AX,DUSP1,TCIM,MOB3B,TOLLIP,RASL10B,DUSP19,C1QL1,EIF1AD,IDH1,NXT2,SNRNP70,BECN1,CENPL,AGPAT1,EDEM1,CSNK2A1,CDC5L,KLF9,SELENOI,COQ10B,SYNCRIP,CEBPG,ZNF280B,GALNT1,VPS4B,SDCBP,PRKCA,KCNAB1,UBE2W,BLCAP,MAEL,GALNT4,TRMT13,MIR29A,TOMM20,RNF113A,RC3H2,CRLF3,PSMG3,FAM110B,SUB1,PTPN11,TNFAIP3,MAT2A,FGFR1OP2,RALA,DUSP3,CSTF3,EZH2,CYB5B,OTULIN,EIF1AX,MARCKSL1,DCUN1D3,MAK16,G3BP1,ANP32B,PCGF6,GCA,ARB2A,TMT1A,KDM2A,ADAT1,CAMSAP2,MRPS35,STOML2,UBXN6,ATG7,CCAR2,COPS7B,OCRL,PHB1,TMEM14A,SLC43A2,VAV2,OTULINL,ATAD1,G3BP2,ZDHHC17,SLC35F2,ACER3,RRN3,CUL3,VEZT,KDSR,ZNF668,AK3,RBBP4,MAD2L1,DIO2,CD79B,CPSF1,RMDN3,ARPP19,SLC30A7,UAP1,RAD23B,CASK,ILF2,YTHDF2,AGPAT5,MLLT6,APH1A,MDC1,HSD17B10,TMX3,SEPTIN7,GK5,TTL,CDC37L1,HDAC6,TOP1,EEF1AKMT3,UBP1,CTDSPL2,HSD17B11,MANBAL,TOX4,TTI2,ATG16L1,HACD2,NUCKS1,USP8,PPP1R2,PRRG1,TMEM209,SIRT7,SLC2A3,SQSTM1,TXNIP,STK24,PPTC7,CSK,AR,TUSC1,NONO,USP14,RUNX1,ATP5F1A,CD47,TENT2,CYRIB,MIR16-1,SELENOT,TRIM24,PDHA1,TAF10,GCLC,TFPI,DCP2,HNRNPF,NAB1,CCAR1,SESN3,GNA11,TRIM21,EWSR1,LAMP2,FAM241A,XPO1,YWHAH,CPEB1,RNF144B,FUBP3,RBM5,FAM219B,RPRD1A,CSRNP1,SH2D1A,CSNK1A1,CNDP2,NUFIP2,EIF4B,UBL3,MTMR6,TOMM22,UFL1,RPS28,TAPBP,CCNI,FBXW11,H2AZ2,PNRC1,CIRBP,DESI2,ZMPSTE24,SERPINH1,PRMT6,HNRNPC,MYC,CPSF2,SLC30A5,ZMAT3,ZCCHC7,PCMTD1,STAT2,CMTR1,VDAC2,DOK4,CAPZA2,BIRC5,FURIN,TP53,STRBP,STX11,SMIM11,PHF1,GLCE,BHLHE40,DHX9,NR4A2,TMEM123,KPNA1,TPM3,API5,PPIL4,FZR1,CAND1,MRPS9,RPRM,ACSL4,XXYLT1,SLC39A10,WWP1,CSNK1G3,CHIC2,AGO1,LITAF,PSEN2,NLE1,BAP1,LIN7C,DDX46,ZBED3,MECP2,GLOD4,CDKN2AIP,PDCD4,IGF2BP1,PSMB2,MTPN,GRPEL2,IFI6,RNASEH1,DYRK1A,RSL24D1,IDE,PPP2R5E,B4GALT1,RIMOC1,BZW2,CHMP4C,RPN1,DHRS3,STX12,DCAKD,ANP32A,RBM12,ACTN4,JUN,FAF2,ACVR1B,TOB2,AHCYL1,SSRP1,UBE2A,CIPC,SLC25A5,PREPL,SKA1,FAM76B,PEDS1,CDK5RAP3,COTL1,MRPS26,HNRNPD,PLAC8,HNRNPA1,TLCD4,NABP1,SPRED2,ATP6V1A,AZIN1,IER2,ANXA7,FKBP1A,IRF2BPL,NUDT3,YTHDF1,ATP2C1,PIGA,ZCRB1,ARHGAP19,CCDC25,TM9SF4,RAB11A,TUBB,TAF11,SUSD6,CNOT6,VPS72,GLIPR2,CTLA4,FAM13B,TM4SF1,CNOT7,RNF115,CDC42SE1,TRPC1,PPIC,FOXP1,BRD3,MICB,DAG1,GOLPH3L,SLC41A1,RAB22A,CGAS,MRPS23,MSMO1,RABL2B,CDK9,PTP4A3,DCK,PRR3,MAP3K12,UBE2F,AP1AR,WTAP,DCTD,SEC22B,KDELR2,GID8,DVL2,PRIM2,SOD1,NDUFC2,ANAPC16,ASCC1,PAIP2,YPEL5,TAF5L,NREP,TMOD3,MGST3,DEK,PHTF2,UBE2L3,CTTN,EIF2AK2,RNF122,SPIN3,ZBTB18 |
| 2.281e-37 | -84.37 | RBM39 (RNA binding motif protein 39) | protein interactions | 9584 | 1021 | 473 | 19454 | 5460 |
TTC33,CHTOP,H1-10,SF3B4,EFHD2,DES,PSMD6,SNRNP40,FBXO22,ATP5F1B,APOBEC3A,SHMT1,EHHADH,RPL27A,NCOA5,EP300,HDAC5,HSPA8,XRCC5,SNRPA,SLU7,MRPS7,SAP18,STAU1,SSR3,HNRNPA0,PPIB,HSPB1,EED,MAGED2,SRSF1,TCP1,EIF2S1,PGR,MED9,UBL5,RPL18,SEC61G,CAAP1,SMNDC1,SREK1IP1,RTCB,PDIA6,CCT8,TOP2B,PABPC1,POLDIP3,HNRNPDL,RPL28,KRAS,RPS17,MAT2A,RPF2,CALU,RRP7A,ATP1A1,ELAVL2,ZBTB38,LSM6,RC3H2,EIF3G,EIF2S2,MRPS28,PSMA6,RPS3,SRPK2,PPP1R10,RPL10L,CFTR,PPP1R8,ACACA,HECTD1,ZNF326,SDCBP,RPA2,RNF113A,HNRNPH2,BANF1,HSPA5,MARS1,RBM22,KDM1A,CSNK2A1,COPS5,PGAM1,TMOD2,RPL10A,RPS2,CDK12,SNRNP70,COX4I1,SYNCRIP,EEF1B2,CDC5L,RBM42,TMPO,NKAP,RPS16,WBP11,ACTR1A,RAP1A,MTCH2,IPO8,PSMC3,ARPC3,IK,TFCP2,TFRC,TLR3,RAB27A,MRPS18B,RPL3,CAPZA1,KPNA2,CDC40,MCM3,MCM4,GRB10,CUL3,RIT1,LMNB1,RPL37A,RAN,EIF3K,ARF1,GNB1,TNPO3,SNRPB2,RPL19,MAD2L1,RPL35,DYNLL1,RBBP4,PRDX3,WDR77,HADHA,G3BP2,PSMC1,COIL,TRA2A,EIF3D,STOML2,MRPS35,SAV1,PRPF19,PSMD3,PRDX1,RPL23,AHSA1,DDX23,HP1BP3,RPLP1,MYEF2,PHB1,FOLR1,BUD31,KCTD10,SPTAN1,RPL7,CCAR2,NOP58,FAM200A,MAK16,KHDC4,E2F4,FEN1,SF3B5,EZH2,RPS24,MCM6,MRPS17,SRSF4,PPWD1,ETFA,RBBP7,TRIM26,NONO,TUFM,GMPS,RUNX1,ATP5F1A,CASC3,ACAT1,RPS20,RTRAF,PRKRA,CYRIB,EIF4A3,RPL22,SLC25A4,RPL13A,TXN,MAGOHB,LDHA,EIF3J,RPS14,PSMC4,SAP30BP,RBFOX2,MACROH2A2,RPLP0,LSM2,HSP90B1,H2AC7,LMNA,MRPS34,PNO1,SIRT7,PRPF4,MME,RPL4,HMGB1,HDAC6,CRBN,RCHY1,HACD3,AIFM1,TOP1,THAP1,RPL15,MAP1LC3B,DDX39A,EEF1A1,YTHDF2,MRPL11,ILF2,HSD17B10,ZC3H11A,SEPTIN7,EIF3E,MDC1,PRDX4,RPS13,THRAP3,LSM4,CTNNBL1,SNRPB,CPSF2,PSMD1,HNRNPC,PSMA4,LDHB,SFN,HNRNPAB,MYC,APOBEC3B,H1-1,MDH1,CRMP1,COP1,RPS26,H2AZ2,CCT2,CKB,MCPH1,SMU1,PRMT5,CMTR1,DLST,VDAC2,ACAP2,RPL10,ESR2,POLR2B,PSMB6,MATR3,ZC3H14,PSMB3,LAP3,TOMM22,TRMT112,NUFIP2,EIF4B,DDX5,SF3B1,RPS28,DDX39B,PHB2,EEF1G,FXR2,TRA2B,SRSF2,UFL1,DDRGK1,CTNNB1,XPO1,ZCCHC10,RPL6,WWP2,DDX50,IFI16,LAMP2,MAGOH,DDX1,WDR82,FUBP3,CCT7,HSP90AB1,SNRPA1,SNRPD3,HNRNPL,RPS10,NOB1,RPS7,EEF2,TUBA1A,DHX38,TRMT1L,RPS23,H2BC1,TUBB4B,RPL31,CCAR1,RPS4X,RUVBL1,PSMA2,HNRNPF,CFL1,RPL7A,SMARCA5,SUGP1,RAB2A,RBM7,UBE2H,IGF2BP1,MACROH2A1,SEC61A1,CSNK2B,PHAX,UQCRC2,PSPC1,SF3B6,DYRK1A,CDC42,TFIP11,DLAT,PGK1,LSM12,BAP1,RPL27,RBM23,STK38,GAPDH,PPIL4,LSM3,AKAP8L,RPL24,CHCHD1,ALYREF,RPL32,MRPS9,RPS27L,FZR1,CAND1,RPSA,TP53,CAPZA2,CBX3,DDX42,DHX9,MAP1B,RPL17,MEPCE,PSMB10,HNRNPK,CSE1L,RPS29,PRPF31,RAB11A,ACO2,HSP90AA1,YWHAZ,FYTTD1,ARHGAP19,ZMAT2,RPS9,SNRPD1,SNRPD2,ERH,PRRC2A,ACTB,TUBB,PRDX2,STXBP1,ARCN1,MFAP1,IRF2BPL,H2AC1,USP39,NKAPD1,YTHDF1,HNRNPA1,MRPS26,HNRNPD,DROSHA,RPLP2,RPL9,RPL8,STK3,DHX15,SRSF10,INA,PPP2R1A,ACTN4,RPL29,JUN,B3GNT2,SNRPE,RPS11,POLR2C,NME1,GDI2,RPN1,SRSF7,MRPS11,PCNA,BCKDK,HNRNPA2B1,SLC25A5,HSPD1,COPS4,SSRP1,PSMD12,DNAJC8,FBXO7,PPIG,RPS12,MSN,SPIN3,TUBA1B,CTTN,ENO1,CCNF,NDN,TMOD3,UQCRC1,UBA52,TXNL4A,SF3A1,RPL26L1,HNRNPH3,PPIH,CLK1,KIN,IDH3A,RPA3,BRIX1,LSM8,FBXW7,PDHB,GRSF1,MOV10,PSMB1,KRR1,ACTA2,RPL12,MRPS23,CWC15,NCBP2,CDK9,THOC1,RPL35A,CD2BP2,CCT5,FBP1,ACTR2,NDUFS3,RPL23A,PQBP1,NKRF,RAB1A,SMN1,FARSA |
| 3.482e-37 | -83.95 | EGFR (epidermal growth factor receptor) | protein interactions | 1956 | 3105 | 1170 | 19454 | 5460 |
RB1CC1,ELP6,ZCCHC9,WDR12,CDK5RAP3,CISH,HNRNPA1,NDC80,PIK3R1,PDIA3,LIPT2,SLC25A26,HMGA1,NUF2,ATP6V1A,MAP1LC3A,PSMB4,MRTO4,RPL9,SPRED2,RPS11,POLR2C,PRKAG1,EXOSC3,BZW2,RPN1,ACTN4,STPG4,FAF2,JUN,DPH5,AHCYL1,SSRP1,PSMD12,GUK1,SRSF7,BAG2,SCYL2,ILK,RPS5,CCDC25,SLC7A11,SCFD1,YWHAZ,BRCA1,ZCRB1,RPS29,JPT1,RAB11A,PMPCA,CDC123,MAD2L2,JAK2,UBE2V2,LGALS3,REEP4,TUBB,RPS9,AP1G2,POLR3B,SNRPD1,VPS72,SKA2,H2AC1,VPS18,VAPB,NOTCH2,PGRMC1,YTHDF1,MED11,CYFIP2,EMG1,BIRC2,ATP2C1,DNAJC3,BRD3,RAB3A,DNAJC4,ENHO,SLC35A5,ATP5MG,PMM2,MICB,TOMM70,CDK9,DCUN1D1,PSMB1,TSR2,EIF4E2,POLR2G,SOD2,ADAMTS1,FCF1,MAP2K3,CCT5,ADORA1,PTGES3,SMN1,FN3KRP,HUWE1,RNF115,IGF1R,TRAPPC1,GRID1,AP2A1,GMNN,TAF5L,VIRMA,GNAI2,RHOJ,ZBTB17,NDN,POLR3H,CTTN,EIF2AK2,CTNNA1,ENO1,MRPL53,GAB1,KRT7,STAMBP,MET,UBAP1,SLC12A2,MAP3K12,STOM,UBE2F,COX6C,SEC22B,PIP5K1A,UBA52,VPS28,LSM8,DAD1,FBXW7,MRPL17,YKT6,PPIH,PRKCB,ZNF319,IDH3A,HELLS,PRIM2,INPPL1,SOD1,NCK1,TOR4A,XPO1,PFDN5,RPL6,CNOT2,FHIP1B,RPS10,YBEY,SH2D1A,RAB35,RPRD1A,HGS,RPS23,TUBB4B,EEF2,TUBA1A,TMBIM1,NUDCD3,DHX38,GCLC,SPC24,TRMT1L,CCAR1,PSMA1,PELI1,EWSR1,MYO1B,RPL31,YAE1,RCL1,FBXW11,CIRBP,CCT2,CPSF2,BAG3,PSMD1,KANSL3,HNRNPC,MYC,NCKAP1,APEX1,ESR2,RPL10,POLR2B,STAT2,GPN2,CMTR1,DLST,KTI12,DOK4,DDIT4,TRMT112,CSNK1A1,EIF4B,GSTM2,IL6ST,PSMB3,DUSP14,MTMR6,TOMM22,EEF1G,UFL1,TMEM203,SF3B1,RPS28,TRMT5,MAP4,SHC1,RPL24,TPM3,GAPDH,API5,FCGR2A,PPIL4,FAR2,USP2,PRR32,DPP4,RAC2,EXT1,RPL32,SSBP1,BIRC5,FURIN,RAD1,DDX42,EXOC3,NDST1,GPR162,CENPM,SNAPC5,RPSA,TP53,IMP3,CSE1L,PSMA5,NUP107,MRPS33,NEDD8,AKAP12,DHX9,SOS2,GLCE,MRPL52,DTL,SLC6A1,AKT1,CARS1,PSMB2,RSL24D1,UBA3,NOPCHAP1,MAP3K3,CTSB,PPP2R5E,B4GALT1,PHAX,ALG2,CDIPT,CYC1,LUC7L3,DYRK2,WWP1,CLU,DNLZ,ST8SIA4,WDR3,DPH3,PSMG4,TXNDC17,NLE1,LIN7C,BAP1,PDCD10,AHSA1,RHOG,MMUT,EMC6,PSMD3,HMBS,PRDX1,OS9,LRWD1,ATXN10,MPP1,SNX1,SPTAN1,RPL7,OCRL,NOP58,RPLP1,PTGDS,XPO5,TSG101,PHB1,DNM2,AP2S1,RNF126,PLD3,SF3B5,EIF1AX,STIM1,MAK16,FEN1,RFC3,SIAE,AP1M1,PPWD1,G3BP1,RPS24,JAK1,SLC39A7,NDUFA4,CGRRF1,MCM3,RFC5,OTUD7B,SAMHD1,RIOK2,CFAP20,CUL3,RRN3,KDSR,USP13,RPL19,SPINDOC,RPL7L1,RBBP4,RPL37A,AP2M1,PARP2,EIF3K,FAU,ARF1,GTF2H5,VAV2,TIMM29,ETF1,RPE,NRDE2,RND2,EHD1,OTULINL,PSMC1,POLA2,ATAD1,RLIM,NUBP2,ATP5F1E,WBP2,TOPBP1,DNAJC7,ESYT1,PET117,HDAC6,GMPPB,ISYNA1,PKIA,G6PD,CAV1,TOP1,EIF2B5,POLR2I,ARF6,SEC23A,SSU72,AIFM1,CTDSPL2,DFFA,ILF2,GABPB1,DMAP1,UAP1,POP5,THAP1,CCDC47,DOK5,EIF3E,SNRPG,SOCS2,RNF20,CTNND1,HSPE1,LSM4,SEM1,HSD17B10,NTRK2,SEPTIN7,GLUL,EHD4,XPOT,ZNHIT3,TXNIP,NONO,AR,TUFM,GMPS,ATP5F1A,SEC13,CSK,CTSD,TECR,RPL13A,TXN,CYRIB,SMAP2,PELP1,GABRA2,PITPNA,TTI2,HSP90B1,PTP4A2,TIMM23,CDK1,P3H1,EDF1,MYL12B,TPT1,ATG16L1,WDR83,NUCKS1,USP8,EIF5B,CERS2,ITGA2,MTDH,GPX4,PNO1,FADS2,NCDN,YWHAB,FKBP4,SHC3,TAX1BP3,LANCL1,RHOH,TCP1,LSM5,FAM98A,MEAF6,EIF2S1,CORO1C,POLR2L,TNIK,RND3,SEC61G,TNPO2,ERRFI1,RPL28,VDAC1,GJB1,RUVBL2,RPAP3,SDHC,ARMC7,NSA2,DNAJB6,ISCA2,TIMP1,HMGCS1,RPL39,TBCE,ATP6AP2,TOM1L1,PSMD6,GPNMB,PSMD4,ANAPC2,PAK2,MRPS18A,ISCU,RPP21,HSH2D,NUP62,RPL27A,RPP14,STK26,COX17,HSPA8,XRCC5,RFC4,SLU7,RPL10A,BECN1,TUBG1,PSMG2,CENPL,TMA16,CSNK2A1,FAM20C,EDEM1,CMSS1,CDC5L,SURF6,PRELID1,ILVBL,TPPP2,ABHD8,LCMT1,RWDD1,MCL1,COX4I1,AIP,SDHB,ITK,PSMC3,TAF2,RNF8,SNAPC2,ACADSB,ARPC3,NHERF1,DNAJC2,SFTPC,IK,CD248,ZMYM4,H2AX,ACTR1A,IPO8,PREB,DUSP19,IMP4,L1CAM,THG1L,ABCE1,RPL3,RBM41,ATP2B4,NAE1,NOSIP,PSMG3,ATP1A1,LSM6,EIF3G,HFE,NCAPG2,TIA1,PTPN11,SUB1,GSTK1,MGST2,NAA50,RPF2,MAT2A,DUSP3,CSTF3,ADRM1,EIF2S2,PSMA6,UTP15,UBE2M,PRKCA,SAMM50,IDH2,WRAP53,VPS4B,NTPCR,CFTR,GTF3C4,CCNH,NDUFAB1,RETN,HSPA5,TOMM20,H2AC13,RAB9A,TWNK,POLD2,SNAPC1,ORC6,PDAP1,MED4,PPM1B,ZNF207,PCNX1,DHX15,WDR44,PRPF18,DIRAS3,HYPK,AFAP1L2,KRT8,RPLP2,PSMB5,RPL8,SNRPE,DOHH,POLR2D,CTNNA2,PPP2R1A,NEU1,NAA15,RAF1,BUD23,SACM1L,COPS4,FLOT1,GTF3C3,S100A10,TRMO,DHX16,SELENOP,PCNA,HNRNPA2B1,HSPD1,VMP1,HSP90AA1,PFDN2,RHOB,SENP8,PRPF31,CAV3,HBEGF,PIK3R3,MTG2,NIBAN2,ACO2,CLIC4,ERH,ACTB,TAB1,RPF1,LAMTOR3,STARD7,POLR2F,SEC61B,GPR89A,SNRPD2,MFAP1,HEXB,ELOVL1,USP39,PSMB7,CEND1,ACTL6A,ATP6V1G1,STX7,RNF11,CSRP1,MRPL57,PPP2R3A,HSCB,PSMA3,CLP1,ECD,GTF2A2,ANKRD49,ATP1B1,PID1,LAMTOR2,ERCC3,H2AC14,COG1,RPL35A,TES,MYBL2,ACTA2,HRAS,PTPN1,RPL12,DHRS7B,VAC14,AP1S2,NDUFS3,ACTR2,GINS4,PGM1,FNTB,CMPK1,HINFP,ADD2,VPS16,APBB3,NOC4L,DNAAF10,NSMCE3,FARSA,VRK1,ANAPC11,RPL23A,LPAR2,TCOF1,RAB1A,COL1A2,CDC73,PRR19,NEURL2,SDF2L1,SKAP2,DNAJC8,RACGAP1,RPL26,CIAO1,DHPS,HSPA14,FAH,FERMT2,UBB,SH3BGRL,COPE,RPS12,CTU1,COA5,GTF2A1,METAP2,TUBA1B,POP7,CAMK2N1,RARS1,METTL14,PICALM,DCTN4,CDK7,GABARAPL2,UQCRC1,MED30,ARHGAP1,RABL3,SF3A1,LIAS,BRIX1,CHMP2B,PIK3R2,ARMCX5,SLC7A1,NF2,SPCS2,DCTN6,RHOU,RPA3,ARMC8,CBL,DEGS1,CTNNB1,DKK1,IFI16,CCT7,HSP90AB1,CHMP2A,TRMT61A,SNRPA1,SNRPD3,SUMO2,OSBP,DBR1,HNRNPL,COCH,WDR82,PRCC,SWAP70,RAB31,PLS3,RPS7,RAB18,TFG,RPS4X,PFDN1,ROCK2,KGD4,RUVBL1,EPHA4,PSMA2,CDK5,ABCF1,LTO1,LSM14A,MDH1,OAZ1,RPS26,PSMD14,SLCO3A1,SNRPB,BTF3,PSMA4,SFN,HNRNPAB,COX6B1,RABIF,PSMB6,NDFIP1,STAT1,TAMM41,MATR3,SMU1,PRMT5,INTS10,MTG1,SLA2,MED31,CAV2,MAP2K1,ZC3H14,USP6NL,TIMM10,SYK,ITGAV,GINS3,PHB2,TRA2B,SRSF2,SLC31A1,DDX5,TMEM106B,ATP6V1D,NUS1,NOL12,DOLK,RPAIN,CD81,CYP4V2,LCP2,MIF,SPPL3,HSD11B1,DSTN,UBE2G2,UBE2N,METAP1,DOK6,GNAI3,NUPR1,CBX3,PIK3CA,ZNF581,MGARP,ESS2,ATP5PB,RPL17,MEPCE,HNRNPK,RPIA,OAT,ATP1B3,MRPS16,GORASP2,DNAJC5,CFL1,CCNB1,RPL7A,CDC20,STAT5A,PTPMT1,SRP54,SEC61A1,UQCRC2,PSPC1,CHPF2,SEPHS2,PTPN22,FGFR1,SYS1,CDC42,CD2AP,MPV17,GTF2H4,RGS2,WDR55,GRPEL1,STK38,CLEC12B,RPS15,NME4,DERL1,GFM1,DPAGT1,PGK1,LSM12,PML,RBM23,RPL27,SEPTIN6,CD58,RPL23,HBA1,DDX23,CSTA,EIF3D,MAP3K14,SAV1,PRPF19,CLPX,SNX2,BUD31,POLR3F,LCA5L,CYB5A,COPS2,IGBP1,GJA1,PPP2CB,WDR6,GNB1L,TMEM204,VPS33A,GTF2E2,NUP153,GFPT1,TXNRD1,E2F4,GSTT1,HS2ST1,MCM6,ZBTB14,ATP6V0B,PPAN,ARGLU1,PLSCR1,AKT2,MORC2,RIT1,EXOC8,ELMO2,FAS,SLPI,GGH,MCM4,RHEB,SOCS5,GRB10,NOP16,TNPO3,GGPS1,CHCHD3,UMPS,RPL35,MB21D2,CDC7,UBE2S,RAN,PELO,ADNP,RNF7,PPARG,RAB6A,TIMM13,IDH3B,PPP1CB,LEAP2,WDR77,SKP1,WASF3,STAP1,MCMBP,TTC1,DCTN3,THOC3,FGR,MPHOSPH10,PSMD7,LRRC40,EMC4,CGB8,CALR,ORC5,AKAP17A,POLE3,ATP5PD,EIF2B2,ALCAM,CD151,CDCA3,PWP2,SOCS4,EHBP1,SRPRA,SRP14,PPP4C,GEMIN7,RPL15,SOCS3,ALG11,EEF1A1,MRPL11,TBK1,RPS13,ARF4,FBXO25,WASL,PAK1IP1,CTNNBL1,CAMK2G,PC,SNAP23,NAPA,EPHA2,LGALS8,HYCC2,PYCR2,AAMDC,CAP2,CDC16,RPL22,ARMC6,SNX3,YES1,ABHD17A,UBASH3B,CFAP298,PTEN,RPS20,UBE2I,CAB39,DTYMK,GANAB,EIF4A3,STUB1,ZNF574,OXSR1,RPLP0,LSM2,CNTN2,JUP,LMNA,ELP3,CNP,TMEM106A,CCND1,RPS14,PSMC4,CPSF4,POLDIP2,NHP2,SMC4,RPL4,HMGB1,DGCR8,DPEP3,RETREG2,PRPF4,AMACR,PPP1R11,NDUFB8,HSPB1,UTP6,PPIB,MRPL9,CIAO3,PGS1,TMEM97,TRAPPC10,MAGED2,SRSF1,RPL18,AAMP,CRKL,UCK2,SMNDC1,RAB4A,SOX2,TRAF2,ARFGEF1,SUPT5H,RANBP1,MAX,UBL5,KRAS,RTCB,RABGGTB,GPM6B,FSTL1,MCAT,POLR1B,ICAM1,H1-10,FTSJ3,LAMTOR1,RUSC2,EPS8,PPP5C,SNRNP40,ATP5F1B,SF3B4,NFKBIB,FDFT1,CTBP1,PLAA,CD59,CNPY3,PAFAH1B1,GOSR2,CLDN4,MRPS7,SAP18,RER1,DNAL4,EP300,RAB5A,FOS,DPH6,SNRPA,HIRA,RPS2,CDK12,SLC35A1,LANCL2,BCAS4,COPS5,RBM17,PGAM1,KARS1,SLC13A5,DKC1,FCHO2,MIOS,RPS16,TRAPPC3,CAMLG,EEF1B2,GTF2B,COQ8A,STT3A,SESN2,GRAP2,TFRC,GLRX5,URM1,MECR,RPAP2,RRM1,SNAP29,FKBP8,PDRG1,SRPRB,CD1B,TRAFD1,ERO1A,PALM2AKAP2,CALU,DNAJC10,TRIM23,PCBD1,EXOC5,RPS17,SRC,BCCIP,SMURF1,PPAT,PRKCE,GABPA,MRPS21,BUB3,KCTD9,PSMC5,MOB4,RPS3,ACACA,GSTP1,HEXIM1,EIF2B3,STX17,RPRD1B,QRSL1,RPA2,FGF13,SNRNP27,MRPL10,DUSP18,MARS1,EIF4E,RBM22,TLR2,EXOSC4,UGDH |
| 8.172e-37 | -83.09 | HEXIM1 (HEXIM P-TEFb complex subunit 1) | protein interactions | 10614 | 902 | 428 | 19454 | 5460 |
ACTA2,KRR1,RPL12,LDLR,PSMB1,MRPL24,MRPS23,MDM2,CDK9,MOV10,H2AC14,EIF5A2,RAB3A,TCOF1,NKRF,RAB1A,RPL23A,FARSA,H2AC6,MRPS18C,CCT5,H2AJ,CD2BP2,AP1S2,ENO1,TUBA1B,CTTN,RAB3C,RPS12,CMBL,HEXIM2,COPE,DEK,UBB,SLC25A31,STK38L,RPL26,SH3BP5L,AP2A1,PPM1G,RPA3,RAB33B,LSM8,UBA52,PIP5K1A,SF3A1,HAUS2,RARS1,HNRNPH3,RPL26L1,KRT7,PSMB5,RPL8,RPL9,KRT8,RPLP2,DHX15,PPIA,EGLN3,NDC80,HNRNPA1,HNRNPD,MRPS26,HNRNPA2B1,HSPD1,SLC25A5,MRPS11,PCNA,CDK20,SSRP1,AHCYL1,PSMD12,RPS27A,RAB6B,RPN1,SART3,SNRPE,RPS11,ENO2,ACKR3,RPS9,SNRPD2,SNRPD1,TUBB,ACTB,PRDX2,EIF4A2,ERH,RAB11A,RPS29,SMARCE1,YWHAZ,LSM14B,SCFD1,HSP90AA1,RPS5,PSMA3,RADX,CMAS,H2AC1,SLC25A3,ARCN1,UBE2N,ALYREF,SSBP1,MRPS9,CDK6,DSTN,MIF,RPS27L,RAB39B,MYL12A,GAPDH,ELOC,PPIL4,CHCHD1,RPL24,H2AC4,MAP4,TAF9,DHX9,RAB3B,CSE1L,HNRNPK,ATP1A2,RPL17,MEPCE,TP53,RPSA,ATP5PB,DISC1,DDX42,SF3B6,PSPC1,CSNK2B,CALML5,DYRK1A,RPL7A,SMARCA5,ST13,CFL2,CFL1,MECP2,MRPS16,IGF2BP1,RPL27,PGK1,RPS15,AGO1,DDX4,FGFR1,CCDC71,RAB35,WDR82,PABPC1L,SNRPA1,SNRPD3,CDK17,HNRNPL,RPS10,RAB1B,HSP90AB1,CCT7,WWP2,DDX50,YWHAG,H2BC17,DDX1,LSM14A,RPL31,CDK5,TRIM21,EWSR1,RUVBL1,PSMA2,HNRNPF,PSMA1,RAB8B,RPS4X,ETFB,TRMT1L,EEF2,RPS7,H1-3,TUBA1A,H2BC1,TUBB4B,PLS3,RPS23,NDUFA12,SURF2,PRMT5,MATR3,TAGLN2,ESR2,RPL10,PSMB6,HNRNPAB,PSMA4,LDHB,PRMT6,HNRNPC,MYC,SNRPB,PSMD1,H2AZ2,PSMD14,CKB,CCT2,CIRBP,H1-1,RPS26,RPS28,DDX5,SF3B1,EEF1G,PHB2,KRT222,SRSF2,PSMB3,MRPL12,GSTM2,NUFIP2,H2AZ1,SRP14,TOP1,ATP5PD,KLHL9,MPG,PSMD7,FGR,DNAJC7,H2AC25,HSD17B10,TAGLN3,HAPSTR1,HSPE1,THRAP3,LSM4,PRDX4,EIF3E,MRPL22,RNF20,RPS13,MRPL11,LBR,EEF1A1,POMT2,SRP72,ILF2,TNFRSF1B,EIF4A3,RPS20,RTRAF,YES1,SLC25A4,LDHA,RAB14,TXN,RPL22,SEC13,AAMDC,NONO,AR,ATP5F1A,EPHA2,CSTB,PRPF4,H2BC12,HMGB1,NUCKS1,SMC4,GTF2I,NPM3,EEF1E1,MYL12B,SNRPN,RPS14,PSMC4,ATG16L1,EDF1,H2AC7,HSP90B1,LSM2,CDK1,MRPS34,LMNA,TOX4,MACROH2A2,RPLP0,PHB1,RPLP1,HP1BP3,PCBP4,RPL7,CCAR2,COPS7B,RAB11B,RAB3D,MRPS35,PRDX1,PSMD3,PRPF19,EIF3D,HBA1,RPL23,RPS24,RBBP7,G3BP1,RFC3,AP1M1,MRPS17,E2F4,TULP3,EIF1AX,EIF3K,RAN,AP2M1,RBBP4,DYNLL1,RPL35,RPL19,CHCHD3,MCM4,RFC5,ATP1A3,RIT1,NUBP2,HADHA,MCMBP,SKP1,POLA2,PSMC1,RAB37,RAB6A,PPP1CB,PRDX3,ATP5PO,MYL6,SYNCRIP,EEF1B2,RPS16,CDC5L,KARS1,CSNK2A1,SNRNP70,RPL10A,CDK12,RPS2,ATP5PF,SLC25A11,EIF1AD,MRPS18B,RPL3,KPNA2,H2BC14,CDK4,RRM1,ACTR1A,H2AX,NHERF1,TAF2,PSMC3,PSMA6,RPS3,MRPS28,PSMC5,RPL10L,MRPS21,PPP1R10,H2BC9,RPS17,DNAJC10,EIF3G,ATP1A1,THUMPD1,BANF1,LCP1,HNRNPH2,TWNK,MRPL41,MARS1,HSPA5,ZC3H15,H2BC11,HEXIM1,GSTP1,UBE2M,S100A8,MAGED2,TCP1,DYNC1I2,EIF2S1,FAM98A,LANCL1,PPIB,DRG1,CCT8,PABPC1,RTCB,PDIA6,ACTR1B,RUVBL2,CHCHD2,H1-6,POLDIP3,HNRNPDL,RAB4A,AAMP,MTA2,SNRNP40,PSMD4,ATP5F1B,GSTM4,FTSJ3,RBM27,H1-10,CHTOP,XRCC5,RFC4,SNRPA,HSPA8,RAB30,STAU1,HNRNPA0,MRPS7,RPL27A,FDFT1 |
| 8.733e-37 | -83.03 | MIDN (midnolin) | protein interactions | 90007 | 617 | 320 | 19454 | 5460 |
FOS,RPS28,XRCC5,DDX39B,DDX5,HSPA8,SF3B1,PHB2,NDUFS2,HNRNPA0,TRA2B,SRSF2,PACSIN3,PSMB3,SLC16A10,TOMM22,RPL27A,CD59,GPC4,PALS2,VDAC2,RRAS2,FBXO22,PSMD6,PSMD4,ATP5F1B,MATR3,RPL10,GADD45G,PSMB6,CBX5,HNRNPAB,PSMA4,HNRNPC,CNRIP1,SLC1A3,PSMD1,H1-10,PSMD14,CKB,NSA2,SLC38A1,TOP2B,GNA11,RPL31,SREK1IP1,MYO1B,TRIM21,VDAC1,RUVBL1,HNRNPF,PSMA2,PSMA1,HNRNPDL,RPS4X,RPL28,RPS7,H1-3,TUBA1A,NCSTN,TUBB4B,RPS23,RPL18,NDUFA12,SRSF1,RAB35,CORO1C,SUMO3,SNRPD3,LYAR,HNRNPL,HSP90AB1,RPL6,SYNJ2BP,CTNNB1,NDUFV2,PPIB,HSPB1,MAGOH,BANF1,RPL27,RPS15,HSPA5,SPTBN1,SAMM50,SSR1,CYC1,UTP15,PSMA6,UQCRC2,RPS3,PSPC1,MACROH2A1,SLC1A1,SEC61A1,PSMC5,ADRM1,RALA,RPL7A,SLC25A1,PSMB2,SMARCA5,RPS17,CFL1,ATP1B3,RAP2C,RRP7A,IGF2BP1,ATP1A1,SLC25A11,DHX9,SLC16A1,RPL3,KPNA2,HNRNPK,PSMA5,RPL17,MTCH2,TP53,ATP5PB,SURF4,RP9,TFRC,SYNGR3,SLC25A24,PSMC3,GNAI3,COX4I1,RPL32,ALYREF,SSBP1,SYNCRIP,SDHB,SLC39A10,ADD1,RPS27L,RPS16,CDC5L,DKC1,SLC38A2,TMPO,COX5A,GAPDH,CD81,TMA16,SNRNP70,RPL24,RPL10A,NOL12,RPS2,HADHA,PSMA3,SLC35F2,RP2,CNTN1,COIL,STX7,PSMC1,RAB6A,PPP1CB,VAPB,PSMB7,ABCB1,ATP5PO,MYL6,SLC25A3,CMTM7,RAN,FAU,GNG12,RPS9,AP2M1,RPL37A,SNRPD1,RBBP4,TUBB,RPL35,ACTB,RPL19,GNB1,ERH,CHCHD3,TOMM40,LMNB1,HSP90AA1,RPS5,SYPL1,HNRNPA2B1,GADD45A,HSPD1,SLC25A5,UBE3A,RPS24,SRSF7,PCNA,KCTD17,SEMA4C,ATP5F1D,SSRP1,FLOT1,PSMD12,RPL29,NME1,MOXD1,RPN1,CYB5B,SNRPE,STX12,KBTBD3,RPS11,PHB1,MRTO4,PSMB4,PSMB5,RPL8,RPL9,WDR6,GJA1,RPL7,SPTAN1,AGK,INA,NOP58,RAB11B,DHX15,TMEM237,PPIA,SRSF10,STOML2,PRDX1,PSMD3,PRPF19,RAP2B,HNRNPA1,NCR3LG1,RPL23,CD58,HNRNPD,H2BC12,RPL4,GTF2I,NPM3,SLC7A1,SLC5A6,PIP5K1A,MYL12B,RPS14,PSMC4,SYNGR2,UQCRC1,STOM,SLC12A2,ZCCHC17,GHITM,LMNA,JUP,TIMM23,HNRNPH3,RPLP0,SCAMP2,CTNNA1,EIF4A3,TUBA1B,ALB,RPS20,CD47,RPL13A,YES1,SLC25A4,TMOD3,MGST3,TXN,GNAI2,DEK,RPL22,UBB,EMILIN1,PPP1CC,NONO,ATP5F1A,RPL26,AP2A1,DLG1,TCOF1,SFXN1,SLC25A10,SNAP23,RPL23A,TRIM63,THRAP3,PTGES3,RIGI,CTNND1,EGR1,SFT2D2,RPS13,RPL15,LBR,EEF1A1,SLC29A1,NDUFS3,SLC35F1,ILF2,ACTA2,RPL12,H2AZ1,HACD3,SRP14,PSMB1,TOP1,RPL35A,PLEKHF2,ARF6,CAV1,ATP5PD,TOMM70,FAM133B,MPG,PSMD7,OSBPL8 |
| 1.086e-35 | -80.51 | BAP1 (BRCA1 associated protein 1) | protein interactions | 8314 | 1313 | 572 | 19454 | 5460 |
IVNS1ABP,STK11,SEC13,PYCR2,CTSD,KPNA6,AR,NONO,GMPS,TUFM,ATP5F1A,RPL13A,TXN,RAB14,LDHA,RPL22,HOMER1,STUB1,PTEN,UBE2I,RPS20,RTRAF,GANAB,PRKRA,HSP90B1,CDK1,MRPS34,RPLP0,EEF1E1,PSMC4,RPS14,EIF3J,COMMD3,SMC4,NUCKS1,HMGB1,RPL4,NPM3,EIF5B,GTF2I,TMEM209,MBD3,SQSTM1,PSMD7,DNAJC7,CALR,GLO1,TOP1,MAPRE2,G6PD,POLE3,HACD3,NAP1L5,SRP14,SEC23A,MSRB3,RAD23B,ILF2,YTHDF2,RPL15,EEF1A1,MAP1LC3B,HSPE1,TOM1,CAMK2G,MSH6,EIF3E,PRDX4,RPS13,GLUL,HINT1,HSD17B10,HAPSTR1,SEPTIN7,MYO6,PFDN6,SP1,FOXI3,CUL3,HNF1B,ALDH1L1,MCM3,MCM4,RBBP4,RPL35,DYNLL1,GNB1,RPL19,RAN,PELO,EIF3K,ELK3,FAU,RPL37A,AP2M1,MYL6,WDR77,PRDX3,TIMM13,PPP1CB,NSFL1C,LZTFL1,SKP1,UNC45A,G3BP2,PSMC1,DCTN3,TTC1,HADHA,PSMD10,RPL23,AHSA1,MRPS35,DPY30,HEBP2,PSMD3,PRPF19,PRDX1,EIF3D,SNX2,ATXN10,RPL7,CCAR2,SPTAN1,COPS7B,NOP58,CETN2,RAB11B,CACYBP,DNM2,COPS2,RPLP1,XPO5,FEN1,MARCKSL1,TPD52,NUP153,ETFA,G3BP1,RBBP7,RFC2,ANP32B,SRSF4,MCM6,DMPK,RPS24,ERP29,EIF3G,CALU,SNX5,ATP1A1,SUB1,MAT2A,RPS17,ADRM1,SRPK2,LIG3,PSMA6,RPS3,SGTA,EIF2S2,PSMC5,MRPS28,EIF2B3,IDH2,TCP11L1,RPA2,ACACA,GSTP1,UBE2M,SPTBN1,AKR7A2,KDM1A,HSPA5,MARS1,EIF4E,BANF1,HCFC2,PRDX6,LCP1,LANCL2,TUBG1,RPL10A,USP15,RPS2,CDK12,PGAM1,KARS1,CSNK2A1,RPS16,CDC5L,TMPO,COMT,EEF1B2,AIP,SDHB,SYNCRIP,AKR1B1,TRAPPC3,PREP,NEFL,ARPC3,TFRC,PSMC3,TBC1D4,TAB2,ACTR1A,KPNA2,CAPZA1,PDRG1,NAE1,PCYOX1L,PALM2AKAP2,IDH1,RPL3,MRPS18B,H1-10,RBM27,FTSJ3,LAMTOR1,PAPOLA,HMGCS1,PSMD6,PSMD4,ATP5F1B,PPP5C,MORC4,EFHD2,PHF21A,PHKB,SF3B4,TPD52L1,FDFT1,SHMT1,PAFAH1B1,RPL27A,STAU1,MRPS7,XRCC5,RFC4,PYM1,STK26,HSPA8,FKBP4,YWHAB,DRG1,PPIB,DYNC1I2,LYAR,TCP1,EIF2S1,FABP5,MAGED2,CORO1C,RPL18,ZRANB2,MTA2,RANBP1,TOP3B,TNPO2,VDAC1,KRAS,PAX6,HNRNPDL,RPL28,PABPC1,CCT8,PDIA6,RTCB,RUVBL2,DNAJB4,SDF2L1,MAPRE1,AP2A1,STK38L,RPL26,CPT2,COPE,PNP,TMOD3,PDCD5,UBE2L3,TUBA1B,CTTN,EIF2AK2,ENO1,RPS12,MSN,DCTN4,RPL26L1,RARS1,SF3A1,PDHB,CHMP2B,IDH3A,SOD1,RPA3,PPM1G,TCEA1,PPIH,NME2,CNN3,MOV10,RPL35A,MRPS23,ACTA2,RPL12,PSMB1,ADAMTS1,ACTR2,VAC14,MLLT11,CCT5,EXOSC8,PGM1,FNTB,TRIM63,DNAAF10,HUWE1,PTGES3,ADD2,SMN1,VTA1,TCOF1,PPP1R12A,RAB1A,FAF1,IGF1R,RPL23A,MRFAP1,YWHAZ,BRCA1,RHOB,LSM14B,RPS5,BAX,SCFD1,PFDN2,HSP90AA1,PYCR1,RPS29,PRPF31,JPT1,ACTB,TAB1,TUBB,PRDX2,EIF4A2,NDUFAF4,CLIC4,PRRC2A,USP5,ENO2,RPS9,SNRPD1,SNRPD2,USP39,KCTD12,PSMB7,ARCN1,FKBP1A,HEXB,FKBP10,PGRMC1,ACTL6A,CYFIP2,STX7,PSMA3,SKIC8,COTL1,PDAP1,RB1CC1,HNRNPD,VPS4A,PDIA3,LIPT2,HNRNPA1,INA,HSBP1,DHX15,PPIA,PSMB4,RPL9,RPL8,KRT8,RPLP2,ATP6V1A,EXOSC3,NME1,GDI2,SNRPE,SART3,JPT2,RPS11,NAA15,RAF1,ANP32A,RPL29,ACTN4,PPP2R1A,S100A10,AHCYL1,SSRP1,COPS4,GTF3C3,RPS27A,PSMD12,HNRNPA2B1,PREPL,NEK9,NUDT5,HSPD1,BAG2,PCNA,GEMIN8,MRPS16,IGF2BP1,RPL7A,AKT1,ST13,PHKA1,CFL1,CFL2,TXNDC12,EIF4H,CTSB,PSPC1,CSNK2B,WWP1,LUC7L3,CDC42,CD2AP,STK38,RPS15,AIF1L,UGP2,NBN,BAP1,LIN7C,RPL27,DDX46,DLAT,PGK1,RPL24,H2AC4,MAP4,TSNAX,AKAP8L,KPNA1,USP2,GAPDH,ELOC,TPM3,API5,RPS27L,MIF,CAND1,MYL12A,ESD,MBD5,ALYREF,RPL32,SSBP1,EXT1,MTAP,ADD1,RAP1B,DSTN,CAPZA2,CBX3,DDX42,SH3GLB1,RPSA,TP53,HNRNPK,CSE1L,PSMA5,AKAP12,SEPHS1,RPL17,PSME1,MEIOB,MAP1B,DHX9,PSMD14,ATG3,S100A11,MRPS25,CIRBP,CCT2,CKB,MDH1,SERPINH1,RPS26,HNRNPC,LDHB,PSMA4,SFN,HNRNPAB,MYC,CREBBP,SNRPB,BAG3,PSMD1,BTF3,TAGLN2,MATR3,APEX1,NCKAP1,RPL10,CBX5,POLR2B,PSMB6,EIF4EBP3,RRAS2,PRMT5,PPT1,AKR1A1,NUFIP2,EIF4B,PSMB3,LAP3,MRPL12,TOM1L2,EEF1G,TRA2B,FXR2,RPS28,PEBP1,DDX39B,DDX5,SF3B1,AK2,GSTO1,DDX1,PFDN5,RPL6,RAB5C,CTNNB1,YWHAG,XPO1,YWHAH,SNRPA1,SNRPD3,RAB1B,RPS10,HNRNPL,CCT7,HSP90AB1,GYS1,PLS3,TUBB4B,RPS23,TRMT1L,RPS7,ELF1,EEF2,RUVBL1,PSMA1,PSMA2,HNRNPF,TFG,PRPS1,DCTPP1,RPS4X,PFDN1,ABCF1,RPL31,EWSR1,SCPEP1,TRIM21,MYO1B |
| 3.516e-35 | -79.33 | FZR1 (fizzy and cell division cycle 20 related 1) | protein interactions | 51343 | 1116 | 501 | 19454 | 5460 |
RPL7,NOP58,RBIS,ZNF593,CACYBP,PHB1,RPLP1,UBE2D1,RPL23,AHSA1,MRPS35,STOML2,PRDX1,PRPF19,PSMD3,CLPX,WDR11,EIF3D,KCTD17,G3BP1,RFC3,RFC2,MRPS17,NDUFA4,TRIP4,RPS24,CTSA,GTPBP1,CDK5R1,TXNRD1,ASPM,NUP153,RBBP4,DYNLL1,RPL35,RPL19,EIF3K,PELO,UBE2S,RAN,CPSF1,FAU,RPL37A,SERINC1,PFDN6,CUL2,DSN1,USP13,MCM3,OTUD7B,RFC5,G3BP2,SKP1,PSMC1,UPF3B,ATP5MK,TTC1,HADHA,RNF7,PCLAF,ATP5PO,ABCB1,MYL6,WDR77,RAB6A,PPP1CB,TOP1,AIFM1,SRPRA,SRP14,HACD3,PWP2,CDCA3,PSMD7,DNAJC7,CTNNBL1,LSM4,MDC1,MSH6,EIF3E,ARF4,RPS13,HSD17B10,ZC3H11A,SRP72,ILF2,YTHDF2,MTA3,TBK1,RPL15,RPL13A,ZNF622,LDHA,RPL22,SEC63,TECR,EIF4A3,STUB1,RPS20,PTEN,FXN,EPHA2,STK11,CDC16,EMILIN1,TUFM,AR,SMC4,NPM3,EIF5B,CYP17A1,PRPF4,PNO1,NCDN,MTDH,H2BC12,LSM2,CDK1,MRPS34,IFRD1,PDCL,RPLP0,CDR2,CCND1,EDDM3B,PSMC4,RPS14,LYAR,PAIP1,EIF2S1,FAM98A,SRSF1,FBXO31,MAGED2,DCAF5,HSPB1,DRG1,RIOX2,MAPK4,CHCHD2,HNRNPDL,CCT8,PABPC1,RBM3,RTCB,PDIA6,RUVBL2,SMNDC1,AAMP,RPL18,ZRANB2,MTA2,TOP3B,HELT,SOX2,SNRNP40,PSMD6,PSMD4,ZNHIT6,ANAPC2,SF3B4,H1-10,RBBP8,NSA2,SSR3,STAU1,UBE2D3,EIF1B,HNRNPA0,MRPS7,XRCC5,PYM1,SNRPA,RFC4,RAB5A,YAF2,HSPA8,PLAA,MRPS18A,RPL27A,NDUFAF3,RPS16,CDC5L,TMPO,RBM42,STT3A,SYNCRIP,SDHB,EEF1B2,TAS2R13,MCL1,BECN1,SNRNP70,SMAD4,RPL10A,CDK12,RBM17,CMSS1,TSEN34,MZT2B,CCL5,GPRASP2,TMA16,TMEM33,CDC40,CAPZA1,SNIP1,TRAFD1,MRPS18B,RAB27A,RBM34,PSMC3,IPO8,CDK4,ZNHIT1,UBL4A,RRM1,ACTR1A,H2AX,ADRM1,MRPS21,BUB3,SRC,CSTF3,PPP1R10,SMURF1,PSMA6,RPS3,SGTA,MRPS28,PSMC5,EIF2S2,SPOP,EIF3G,PTTG1,ANAPC4,MORF4L1,MAT2A,SLC6A6,RPS17,ANAPC15,MRPL41,MRPL40,UBE2K,MARS1,HSPA5,ZC3H15,BANF1,HNRNPH2,EXOSC4,NEK2,GTF3C4,DHX15,SRSF10,PRPF18,PSMB4,PSMB5,RPL9,RPLP2,KRT8,PPM1B,MRPL18,SKIC8,MPHOSPH6,HNRNPD,MRPS26,MED4,ZNF207,ATP5F1D,CDK20,AHCYL1,PSMD12,GTF3C3,HNRNPA2B1,BAG2,SRSF7,PCNA,BZW2,GDI2,CTNNA2,SART3,SNRPE,CKS1B,ANP32A,BUD23,CSNK1E,JUN,PPP2R1A,MAD2L2,PRRC2A,TRMT6,GRIA1,RPS9,SEC61B,SNRPD2,YWHAZ,LSM14B,HSP90AA1,PFDN2,RPS5,PFDN4,PYCR1,RPS29,PRPF31,YTHDF1,PSMA3,TERT,LARP4B,PSMB7,VAPB,USP39,SLC25A3,ARCN1,GJC1,CDKN1A,RPL35A,NAT2,MRPS23,NCBP2,PTP4A3,KRR1,RPL12,RB1,PSMB1,OSBPL8,ID1,GRSF1,MOV10,TMBIM6,FARSA,NOC4L,ANAPC11,HUWE1,PTGES3,TCOF1,NKRF,SFXN1,MRFAP1,RPL23A,NDUFS3,FAM169A,CCT5,CD2BP2,MAP2K3,RPP25L,COPE,PDCD5,UBB,EIF2AK2,POP7,CCNF,RPS12,ASCC1,DNAJC19,CDC73,YPEL5,GMNN,RACGAP1,RPL26,FBXW7,NF2,MRPL17,PDHB,UQCC3,PPM1G,HELLS,PPIH,KIN,ANAPC16,WTAP,HNRNPH3,MET,PIP5K1A,SF3A1,CCNA2,SNRPA1,SNRPD3,NOB1,RPS10,HNRNPL,DBR1,HSP90AB1,CCT7,PSME2,WDR82,CDC23,RPL6,CDC26,PFDN5,LAMP2,BAZ1B,QPCTL,CTNNB1,YWHAH,YWHAG,XPO1,RUVBL1,PSMA2,HNRNPF,EPHA4,PFDN1,RPS4X,ABCF1,RPL31,CDK5,PTRH2,RPS23,TRMT1L,EEF2,RPS7,ANAPC13,MATR3,RPL10,APEX1,POLR2B,NPPC,VDAC2,MCPH1,PRMT5,DKK3,SMU1,MRPS25,PSMD14,CCT2,CKB,CIRBP,SERPINH1,RPS26,HNRNPAB,LDHB,HNRNPC,PSMA4,MYC,BAG3,CPSF2,SNRPB,PSMD1,EEF1G,NDUFS2,FXR2,TRA2B,RPS28,DDX39B,DDX5,SF3B1,CKS2,TRMT112,CSNK1A1,EIF4B,NUFIP2,PSMB3,MRPL12,TMED9,FZR1,RPL32,ALYREF,SSBP1,MRPS9,CDK6,RAP1B,SMCHD1,TMEM70,RPL24,TSNAX,MAP4,LSM3,AKAP8L,COX5A,GAPDH,ELOC,HNRNPK,PSMA5,RPL17,DHX9,CAPZA2,ID4,RPSA,TP53,DYRK1A,CDC20,PHAX,RBMX2,SRP54,CHRAC1,CISD1,MRPS16,RBM7,EXOSC1,IGF2BP1,CCNB1,RPL7A,AKT1,PSMB2,ST13,CFL1,RPS15,NME4,RPL27,LSM12,ELOF1,RNF34 |
| 7.710e-35 | -78.55 | BIRC3 (baculoviral IAP repeat containing 3) | protein interactions | 330 | 1335 | 577 | 19454 | 5460 |
CCT7,HSP90AB1,SNRPA1,SNRPD3,RPS10,HNRNPL,WDR82,FUBP3,RBM5,RPRD1A,DDX1,XPO1,RPL6,DDX50,BAZ1B,PRPS1,TFG,CCAR1,RPS4X,RUVBL1,PSMA1,PELI1,HNRNPF,MMP9,SCPEP1,MYO1B,ABCF1,RPL31,RPS23,PDHA1,PLS3,RPS7,EEF2,ETFB,DHX38,NCKAP1,RPL10,POLR2B,MATR3,TAGLN2,SMU1,PRMT5,DLST,VDAC2,MDH1,RCL1,SERPINH1,KIF3C,RPS26,PSMD14,CKB,CCT2,SNRPB,STX16,PSMD1,HNRNPC,PSMA4,LDHB,HNRNPAB,PHB2,EEF1G,SRSF2,TRA2B,UFL1,NDUFS2,DDX5,SF3B1,PEBP1,DDX39B,CD40,LAP3,MYL12A,SLC38A2,LMAN1,MIF,TMED9,CAND1,RAP1B,ALYREF,UBE2N,MRPS9,SSBP1,MAP4,RPL24,SMCHD1,BCL10,TPM3,GAPDH,API5,RDH11,RPL17,HNRNPK,CSE1L,NUP107,PSMA5,PDE12,DHX9,CLPB,BIRC5,SLC25A24,CAPZA2,CBX3,DDX42,RPSA,TP53,ATP5PB,IDE,MACROH2A1,CSNK2B,SEC61A1,CALML5,UQCRC2,PSPC1,OAT,IGF2BP1,ATP1B3,GLOD4,ST13,CFL1,RPL7A,NUDT4,SMARCA5,CHST13,RAB2A,TRIM32,PSMB2,WDR3,HDAC3,GFM1,DLAT,PGK1,ITM2B,RPL27,LUC7L3,SSR1,CDC42,NUP35,DHX15,EGLN3,SRSF10,PPIA,AGK,RPLP2,ATP6V1A,PSMB5,MRTO4,RPL9,RPL8,VPS4A,HNRNPD,HAX1,WDR12,SKIC8,ZNF207,HNRNPA1,PDIA3,SACM1L,RAD21,COPS4,SSRP1,FLOT1,GTF3C3,PSMD12,ASF1A,TNF,DHX16,SRSF7,PCNA,HNRNPA2B1,SLC25A5,NEK9,HSPD1,SART3,RPS11,STX12,GDI2,RPN1,ERLIN2,ACTN4,PPP2R1A,RPL29,FAF2,CSNK1E,HSDL2,RAF1,ANP32A,MAT2B,TAB1,CD40LG,PRDX2,SEC61B,RPS9,SNRPD1,SNRPD2,HTRA2,RPS5,IRF1,SMARCE1,RAB11A,PMPCA,F2,PYCR1,ACO2,AZGP1,CDSN,NOP53,CYFIP2,TMEM117,PSMA3,BIRC2,ARCN1,SLC25A3,KCTD12,VAPB,PGRMC1,ACTL6A,TOMM70,THOC1,RPL35A,PSMB1,KRR1,PTPN1,RPL12,TESK1,POR,ATP5MG,GRSF1,PTGES3,FN3KRP,NOC4L,VRK1,FARSA,HUWE1,RPL23A,SFXN1,TCOF1,RAB1A,ACTR2,NDUFS3,UBE2V1,CCT5,DEK,UBB,UBE2L3,COPE,RPS12,TUBA1B,CTTN,ENO1,EIF2AK2,MAPRE1,CDC73,AP2A1,RACGAP1,DNAJC8,FBXO7,BRIX1,PDHB,RTN4,IDH3A,RARS1,RPL26L1,HNRNPH3,UQCRC1,SEC22B,SF3A1,LANCL1,PNPLA8,LYAR,TCP1,EIF2S1,MAGED2,CORO1C,S100A8,SRSF1,DRG1,HSPB1,FKBP4,IKBKB,UTP6,PPIB,RIOX2,HNRNPDL,POLDIP3,RPL28,VDAC1,SEC11A,RTCB,PDIA6,RUVBL2,TOP2B,CCT8,PABPC1,RPL18,CRKL,MTA2,ZRANB2,KCTD16,TRAF2,RANBP1,SUPT5H,PPP5C,PSMD6,SNRNP40,ATP5F1B,PSMD4,CHTOP,H1-10,FTSJ3,PLA2G15,STAU1,HNRNPA0,UBE2D3,EMC1,EP300,MROH8,HSPA8,XRCC5,RFC4,SNRPA,NCOA5,ADSS2,TANK,RPL27A,NUP62,CDC5L,TMPO,DKC1,RPS16,AKR1B1,COX4I1,EEF1B2,SDHB,SYNCRIP,STT3A,USP15,RPL10A,RPS2,SNRNP70,BECN1,LANCL2,CSNK2A1,XAF1,PGAM1,KARS1,CAPZA1,CHST2,RBCK1,SRPRB,TMEM33,KPNA2,ERO1A,ABCE1,RPL3,SLC16A1,SLC25A11,PSMC3,IK,ACOT13,TLR3,TFRC,GPD2,ACTR1A,CDK4,IPO8,MTCH2,TRAF1,BCCIP,CSTF3,BUB3,RALA,PSMC5,EIF2S2,PSMA6,LIG3,RPS3,RRP7A,CALU,ATP1A1,RPS17,TNFAIP3,RPF2,MAT2A,HSPA5,MARS1,ZC3H15,EIF4E,RBM22,KDM1A,PRDX6,RAB9A,APMAP,UTP15,UBE2M,GSTP1,ZNF326,SAMM50,IDH2,RPRD1B,SDCBP,RPA2,SUMO1,SPTBN1,CACYBP,NDUFS8,SNX2,ATXN10,RPL7,CCAR2,SPTAN1,NOP58,RPLP1,XPO5,TSG101,PHB1,WDR6,THOC2,RPL23,AHSA1,TRAF6,CSTA,UBE2D1,EIF3D,TRA2A,STOML2,MRPS35,CLPX,PRPF19,PSMD3,PRDX1,ANP32B,RFC2,RFC3,MCM6,AP1M1,ETFA,G3BP1,EMC8,ERP29,RPS24,NDUFA4,GNB1L,NUP153,GFPT1,MAK16,FEN1,GNB1,SNRPB2,RPL19,CHCHD3,RPL35,RBBP4,RPL7L1,RPL37A,AP2M1,RAN,CYB5R3,ARF1,CPSF1,LMNB1,RBM15B,MCM3,MCM4,TOMM40,RFC5,SAMHD1,G3BP2,PSMC1,COIL,HADHA,CCDC86,NUP50,CXCR4,THOC3,MYL6,ATP5PO,ETF1,PRDX3,IDH3B,WDR77,G6PD,DBT,SEC23A,PWP2,RCHY1,SRP14,H2AZ1,HACD3,DFFA,AIFM1,DNAJC7,ESYT1,PSMD7,GLO1,CALR,NFKB1,MSH6,EIF3E,MDC1,PRDX4,RNF20,RPS13,ARF4,CTNND1,OLA1,THRAP3,HSPE1,PAK1IP1,CTNNBL1,PC,EMC2,HSD17B10,ZC3H11A,SEPTIN7,GLUL,EHD4,NSDHL,LTBR,RAD23B,ZFAND2A,SRP72,ILF2,GGCT,RPL15,LBR,EEF1A1,CCDC47,SEC63,RPL22,RPL13A,CD47,TXN,LDHA,ACAT1,UBE2I,RPS20,RTRAF,GANAB,EIF4A3,TNFRSF1B,SCAMP2,PELP1,CA2,CHORDC1,NONO,KPNA6,TUFM,ATP5F1A,PYCR2,CTSD,POLDIP2,MBD3,NHP2,SMC4,NUCKS1,RPL4,HMGB1,EIF5B,NPM3,GTF2I,ARPC2,MAVS,SQSTM1,MTDH,CSTB,PRPF4,EPHX1,RPLP0,NOL7,H2AC7,HSP90B1,MRPS34,JUP,LMNA,CDK1,RPS14,PSMC4 |
| 1.798e-33 | -75.40 | CCNF (cyclin F) | protein interactions | 899 | 2063 | 818 | 19454 | 5460 |
YTHDF2,CCDC47,UAP1,CASK,ILF2,PPME1,GLUL,HINT1,HSD17B10,TMX3,ZC3H11A,SEPTIN7,HSPE1,LSM4,EIF3E,MRPL22,OLA1,CTNND1,GMPPB,ISYNA1,ESYT1,SLC2A1,DNAJC7,SSU72,AIFM1,SEC23A,HSD17B11,MAPRE2,TOP1,EIF2B5,G6PD,SLC25A12,TPT1,MYL12B,EIF3J,HSP90B1,CDK1,FADS2,PNO1,CSTB,NCDN,MAVS,SQSTM1,USP8,TMEM209,NDUFB10,RETSAT,NONO,TUFM,GMPS,USP14,ATP5F1A,XPOT,SMAP2,PELP1,ACAT1,RTRAF,RPL13A,TXN,TECR,FEN1,STIM1,PLD3,OTULIN,NDUFA4,UBE3A,RPS24,ERP29,ETFA,G3BP1,LASP1,ANP32B,EIF2D,RFC3,PPWD1,STOML2,PSMD3,PRDX1,PSMD10,CAMSAP2,SLC25A21,AHSA1,PHB1,HP1BP3,XPO5,ATXN10,CCAR2,RPL7,SPTAN1,NOP58,NTMT1,MYL6,NDUFA5,ATP5MK,NUBP2,NSFL1C,G3BP2,UNC45A,PSMC1,ALDH1L1,DSN1,MCM3,RFC5,SAMHD1,OTUD7B,MYO6,EIF3K,FAU,CPSF1,SARM1,SLC30A7,AP2M1,RPL37A,RPL7L1,RBBP4,RPL19,MAD2L1,CDK4,IPO8,PREB,UBIAD1,ACTR1A,DNAJC2,ACADSB,IK,GPD2,PSMC3,ABCE1,RPL3,SLC16A1,KPNA2,TOLLIP,ACOT8,SNRNP70,TMEM11,RPL10A,SYNCRIP,SDHB,AIP,LCMT1,SURF6,CDC5L,SLAIN2,ILVBL,SPTBN1,NTPCR,IDH2,VPS4B,UBE2M,POLD2,PRDX6,UBE2K,ZC3H15,TOMM20,MED22,SUB1,MAT2A,RPF2,NCAPG2,EIF3G,ATP1A1,PSMA6,PAFAH1B3,DHRS13,ADRM1,ROCK1,TOP3B,KIF2A,PNMA2,MTA2,RBM3,PABPC1,PDIA6,RPAP3,RUVBL2,VDAC1,HNRNPDL,RPL28,GSTM3,STK4,FKBP4,YWHAB,CORO1C,TCP1,FAM98A,EIF2S1,LANCL1,RPL27A,NDUFAF3,YIPF5,UBAC2,SIGMAR1,KLC2,XRCC5,AKAP1,HSPA8,STAU1,PITHD1,HNRNPA0,PAPOLA,RBM27,NSA2,THTPA,ZNHIT6,LORICRIN,PSMD6,FBXO22,USP16,PSMD4,CCT5,CD2BP2,MAP2K3,CAMK1,MLLT11,FN3KRP,HUWE1,H2AC6,PTGES3,SMN1,SLC25A46,MUL1,EIF4E2,WDCP,PSMB1,NKIRAS2,SEC22B,UBA52,COQ8B,ZCCHC17,STOM,COX6C,AGAP1,IDH3A,HELLS,PPM1G,PDHB,VPS28,MRPL20,LSM8,PIAS1,TAF5L,GMNN,PPIG,CTTN,ENO1,TMOD3,MGST3,PDCD5,GNAI2,UBE2L3,RBM12,RPL29,ACTN4,FAF2,RIMOC1,PRKAG1,RPN1,SKA3,SART3,JPT2,RPS11,UCKL1,STX12,POLR2C,NEK9,SLC25A5,NUDT5,ZYX,SRSF7,BAG2,SKA1,SLC39A3,FANCG,UBE2A,PSMD12,MAP1S,NDC80,PDIA3,HNRNPA1,WDR12,SKIC8,HNRNPD,HAX1,PSMB4,MRTO4,RPL9,ATP6V1A,SNX17,AGK,NOTCH2,AGTRAP,VPS18,KCTD12,ARCN1,ANXA7,FKBP1A,SLC25A3,ATP2C1,TXNL1,SRI,YTHDF1,RADX,SRM,YWHAZ,FYTTD1,ILK,RPS5,GNG12,RPS9,SNRPD1,LGALS3,TUBB,EIF4A2,ABHD12,RPSA,TP53,IMP3,CAPZA2,SURF4,DDX42,SH3GLB1,DHX9,CLPB,CSE1L,PSMA5,PDE12,FAR2,ELOC,LYPLAL1,TPM3,GAPDH,PPIL4,RPL24,MAP4,KPNA1,LSM3,RPL32,ITGA6,SSBP1,GNPAT,XXYLT1,SLC39A10,FZR1,CAND1,CYC1,LUC7L3,TFIP11,NLE1,WDR3,NUDT1,SMARCA5,PSMB2,SLC25A1,AKT1,CNNM4,DTL,IGF2BP1,PDCD4,CDIPT,SF3B6,MACROH2A1,CSNK2B,TXNDC12,CTSB,DHX38,TRMT1L,TUBA1A,TUBB4B,HGS,RPS23,GNA11,FBXO3,RPL31,EWSR1,MYO1B,PSMA1,DCP2,HNRNPF,PRPS1,CCAR1,RPL6,CNOT2,QPCTL,XPO1,YWHAH,ARHGAP5,FUBP3,AASDHPPT,RPS10,PEG10,GPC4,CSNK1A1,TRMT112,CNDP2,NUFIP2,EIF4B,RPS28,ACTMAP,GPHN,SF3B1,EEF1G,LDHB,HNRNPC,CPSF2,UFD1,BAG3,PSMD1,ATG3,FBXW11,H2AZ2,CCT2,SERPINH1,PDF,CMTR1,VDAC2,HDDC2,NCKAP1,RPL10,POLR2B,MRPL11,TBK1,RPL15,EEF1A1,LBR,SLC25A20,DLG1,PC,THRAP3,WASL,MSH6,PRDX4,RPS13,ARF4,GMPPA,CALR,GLO1,HACD3,SRP14,PSMC4,RPS14,CNP,ELP3,JUP,MACROH2A2,RPLP0,PRPF4,H2BC12,SMC4,RPL4,GTF2I,PYCR2,CDC16,KPNA6,PPP1CC,CA2,EIF4A3,SCAMP2,STUB1,UBE2I,RPS20,GANAB,SLC25A4,ARMC6,RAB14,LDHA,RPL22,DNPH1,VKORC1L1,TXNRD1,GFPT1,NUP153,GTPBP1,RBPJ,GNB1L,ARGLU1,PPAN,AKT2,RBBP7,HS2ST1,RFC2,MCM6,PRPF19,CLPX,TRAF6,DDX23,PPP3CA,RPL23,WDR6,THOC2,COPS2,IGBP1,CACYBP,WDR77,PRDX3,PPP1CB,IDH3B,ATP5PO,HADHA,TTC1,MCMBP,SKP1,NT5C3A,CUL2,GGH,MCM4,LMNB1,FAS,RAN,PELO,CDC7,LRRC1,DYNLL1,TSN,UMPS,RPL35,TNPO3,SNRPB2,GNB1,CHP1,MTCH2,RRM1,SNAP29,RPAP2,TMEM165,TFRC,TBC1D4,SLC25A11,TRAFD1,ERO1A,SRPRB,TMEM33,CAPZA1,FKBP8,RBM17,KARS1,LANCL2,SMAD4,USP15,RPS2,CDK12,GLT8D1,EEF1B2,STT3A,COQ8A,NKAP,FCHO2,RPS16,TMPO,TRAM1,EIF2B3,STX17,RPRD1B,HECTD1,ACACA,UGDH,EXOSC4,HNRNPH2,MARS1,DNAJC10,ZBTB33,RPS3,GTF2H2,PSMC5,PPAT,MRPS21,SRPK2,MYG1,SUPT5H,UBL5,UCK2,NUDT19,AAMP,RPL18,CCT8,TOP2B,SREK1IP1,RTCB,IQSEC1,PPIB,DRG1,HSPB1,SRSF1,FABP5,MAGED2,DYNC1I2,PAIP1,SHMT1,NEK7,SDC2,CTBP1,ADSS2,FDFT1,SNRPA,RER1,RNF5,MRPS7,PCCB,MLF2,H1-10,FTSJ3,LAMTOR1,THOC6,SF3B4,SNRNP40,TIMM21,TCEAL1,ATP5F1B,IREB2,TMEM126A,NDUFS3,ACTR2,DHRS7B,SFXN1,GARRE1,TCOF1,NKRF,PPP1R12A,RPL23A,DNAJC30,FARSA,FASTKD5,VTA1,GRSF1,MOV10,ATP1B1,ECD,EIF5A2,CNN3,PTPN1,RPL12,TES,DECR2,MYBL2,RPL35A,SYNGR2,RABL3,SF3A1,UQCRC1,SLC35E1,METTL2A,RARS1,HNRNPH3,RPA3,RTN4,SPCS2,SLC7A1,CIAO1,ZNF687,RACGAP1,HMOX2,RPL26,MAPRE1,HERC4,CDC73,SMAD2,LRP6,CCNF,SFXN2,RPS12,GNPDA1,ALB,CMBL,RPP25L,PNP,CEP97,SCML2,MACO1,CSNK1E,NAA15,RAF1,LYPLA1,ERLIN2,PPP2R1A,GDI2,SNRPE,DTWD2,HNRNPA2B1,HSPD1,PCNA,PRPSAP1,S100A10,GTF3C3,ATG9A,PPM1B,DICER1,DCAF11,VPS4A,PSMB5,RPL8,RPLP2,SNX18,DHX15,PPIA,TOR1AIP2,ACTL6A,LARP4B,ISOC1,MFAP1,EXD2,PSMA3,SMARCE1,VMP1,PFDN2,HSP90AA1,SEC61B,SNRPD2,ACTB,ERH,NDUFAF4,PRRC2A,MAT2B,ESS2,CBX3,RP9,GNAI3,CAPN2,MAP1B,HNRNPK,RPL17,MEPCE,EDC3,MED27,AKAP8L,ALYREF,UBE2N,NT5DC1,RPS27L,MIF,CDC42,CD2AP,SSR1,HPS6,TMEM263,PML,DLAT,PGK1,LSM12,FTSJ1,HDAC3,UGP2,CCNB1,RPL7A,TRIM32,ST13,CFL1,MRPS16,CISD1,OAT,UQCRC2,PSPC1,PTPMT1,RBMX2,SYNGR1,SEC61A1,CDC20,RPS7,NCSTN,H2BC1,PTRH2,PLS3,SMARCB1,ABCF1,LSM14A,CDK5,XPNPEP1,RUVBL1,IMPA2,RAB18,TFG,RPS4X,PTDSS1,RAB5C,CTNNB1,YWHAG,DRG2,AK2,GSTO1,CDC23,DDX1,CBL,HDHD5,PSME2,WDR82,SNRPA1,OSBP,ECHDC1,RAB1B,HNRNPL,TTC9C,CCT7,HSP90AB1,PPT1,PEBP1,DDX39B,DDX5,PHB2,FXR2,SRSF2,TRA2B,TMEM177,NDUFS2,PSMA4,HNRNPAB,COX6B1,S100A11,PSMD14,MRPS25,CKB,RPS26,CHAC2,GGT7,RRAS2,PRMT5,TAX1BP1,STAT1,MATR3,TAGLN2,PSMB6 |
| 3.611e-33 | -74.70 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 948 | 435 | 19454 | 5460 |
AK2,DDX1,ARMC8,RPL6,YWHAG,YWHAH,PHKG1,CTNNB1,RPS10,HNRNPL,PEG10,CCT7,HSP90AB1,PSME2,TUBB4B,HGS,DHX38,TUBA1A,RPS7,EEF2,DCP2,HNRNPF,ROCK2,RUVBL1,RPS4X,TFG,RAB8B,S100B,ABCF1,CDK5,TRIM21,EWSR1,CIRBP,CCT2,CKB,RPS26,MDH1,SERPINH1,CREBBP,CNRIP1,COX6B1,LDHB,HNRNPC,SFN,HNRNPAB,SLC1A3,UFD1,BAG3,STAT1,APEX1,ACAP2,RPL10,VDAC2,SMU1,NUFIP2,EIF4B,CNDP2,CSNK1A1,SYK,TOM1L2,EEF1G,PEBP1,H2AC4,KPNA1,MAP4,CXCL12,TPM3,API5,SNAP25,SSBP1,KIAA0513,UBE2N,ADD1,DSTN,PIK3CA,CBX3,CAPN2,SYNGR3,KBTBD4,GNPNAT1,ATP1A2,PDE12,RPIA,HNRNPK,ZNF365,SEPHS1,MAP1B,YIF1A,NPTX1,SLC25A1,AKT1,RAB2A,CARS1,CFL1,CFL2,EIF4H,CHMP5,DYRK1A,SYNGR1,GNAO1,MACROH2A1,DYRK2,CYC1,CDC42,AGO1,CD2AP,MND1,HDAC3,STK38,CLU,SEPTIN6,TRIM3,HAX1,HNRNPD,COTL1,PDAP1,PDIA3,PIK3R1,PPP2R5A,MAP1S,HNRNPA1,INA,RPL9,PSMB5,TYMS,RPLP2,ATP6V1A,CTNNA2,PPID,GDI2,CHMP4C,STX12,MAPK10,PPP2R1A,OTUD6B,FAF2,SLC25A5,HSPD1,HNRNPA2B1,GDAP1L1,SRSF7,BAG2,YWHAZ,BRCA1,RPS5,HSP90AA1,ACO2,RAB11A,F2,GSTM5,ELMOD2,EIF4A2,ACTB,TUBB,ERH,USP5,S100A6,ENO2,GLIPR2,SNRPD1,SEC61B,RPS9,PSMB7,FKBP1A,CEND1,STXBP1,NUDT3,YTHDF1,STX7,CSRP1,ATP6V1G1,JADE1,NME2,KIAA1143,CNN3,RAB3A,PMM2,RAB22A,HTRA1,PTPN1,RPL12,ACTA2,RB1,MAGEA4,MT1E,PSEN1,VTA1,ABHD10,PTGES3,ADD2,RAB1A,GNG5,SMAD2,MAPRE1,RPL26,TMOD3,UBB,PDCD5,GNAI2,CCNF,CTTN,METAP2,TUBA1B,CTNNA1,RPS12,MSN,SLC12A2,CARHSP1,SH3GLB2,HNRNPH3,SEC22B,UBA52,UQCRC1,UBLCP1,SYNRG,PDHB,YKT6,NF2,DVL2,DCTN6,PRKCB,RTN4,FKBP4,YWHAB,HSPB1,GSTM3,PPIB,NT5C2,EIF2S1,GFOD1,PNPLA8,UQCRH,LANCL1,TNIK,CORO1C,PPFIA3,STMN2,TPPP,SLC1A2,RANBP1,TNPO2,RPL28,PABPC1,CCT8,RUVBL2,ACTR1B,H1-10,ELAVL4,TBCE,CASP4,PPP5C,CTBP1,RPL27A,SHMT1,PAFAH1B1,UBE2D3,EMC1,OXCT1,STAU1,PYM1,HSPA8,EP300,SNRNP70,LANCL2,RPL10A,ACOT8,PGAM1,CSNK2A1,ARL6IP5,RPS16,CD99L2,SYNCRIP,EEF1B2,ARMC1,TFRC,PSMC3,SNAP29,MTCH2,ACTR1A,DUSP1,TOLLIP,PALM2AKAP2,RAB13,RRP7A,SNX5,PTPN11,TIA1,RPS17,PRKCE,ADRM1,SRC,TFEB,SRPK2,RPS3,ATL1,EIF2S2,PSMC5,H2BC11,IDH2,UBE2M,GSTP1,SCLT1,PRKCA,TRIM36,CAPN1,UBE2W,NDUFAB1,KDM1A,NAPG,UBE2K,MRPL40,TOMM20,HSPA5,SNCG,PRDX6,TRAF6,PSMD10,AHSA1,RPL23,NQO1,PSMD3,CRIP1,RAB3D,SPTAN1,RPL7,CACYBP,NDUFS8,RAB11B,DNM2,PPP2CB,THY1,RPLP1,VAMP2,PPFIA2,EIF1AX,CDK5R1,GTPBP1,TPD52,SNCB,TXNRD1,GFPT1,G3BP1,LASP1,RBBP7,GNL1,ETFA,SRSF4,NDUFA4,ERP29,ATP1A3,MYO6,FCER1G,PFDN6,ALDH1L1,SCG3,TOMM40,RPL35,RPL19,RAN,ARPP19,AP2M1,SARM1,ATP5PO,TIMM13,PPP1CB,RAB6A,NSFL1C,GPM6A,ATAD1,PSMC1,G3BP2,ATP5IF1,HADHA,SLC2A1,CALR,AMT,SNAP91,HDAC6,MAPRE2,G6PD,SRPRA,SRP14,PWP2,ILF2,CASK,PDLIM4,APEH,EEF1A1,MAP1LC3B,PGM2L1,BCS1L,RPL15,GPR37L1,CTNND1,ARF4,DLG1,HINT1,TAGLN3,CA2,PEA15,CAP2,CTSD,NDUFB10,SEC13,NONO,PPP1CC,USP14,TUFM,LDHA,SLC25A4,STUB1,CYRIB,PRKRA,GSK3A,RTRAF,RPS20,UBE2I,CDK1,JUP,HSP90B1,RPLP0,PDIA2,MACROH2A2,RPS14,ATG16L1,PSMC4,TPT1,EDF1,DGCR8,EIF5B,RPL4,AATF,ARPC2,H2BC12,SQSTM1 |
| 1.096e-32 | -73.59 | MEPCE (methylphosphate capping enzyme) | protein interactions | 56257 | 839 | 394 | 19454 | 5460 |
PSMC5,MRPS28,PSMA6,RPS3,PPP1R10,RPL10L,MRPS21,RPS17,H2BC9,MAT2A,LSM6,RNF113A,HNRNPH2,THUMPD1,HSPA5,NTPCR,SNRNP27,UBE2M,HEXIM1,H2BC11,RPA2,SYNCRIP,EEF1B2,RPS16,CSNK2A1,USP15,RPL10A,RPS2,SNRNP70,MRPS18B,RPL3,SNIP1,H2BC14,KPNA2,H2AX,ACTR1A,PSMC3,TAF2,GTF2F1,SF3B4,SNRNP40,PSMD6,FBXO22,PSMD4,ATP5F1B,RPL39,CHTOP,FTSJ3,EP300,HSPA8,XRCC5,RFC4,MRPS7,STAU1,HNRNPA0,PABPC5,RPL27A,MAGED2,SRSF1,TCP1,LSM5,ZNF511,PPIB,MRPL9,DRG1,YWHAB,ACTR1B,PDIA6,RUVBL2,PABPC1,RBM3,CCT8,POLDIP3,HNRNPDL,RPL28,H1-6,KRAS,CHCHD2,ISG15,SOX2,STBD1,RPL18,MTA2,ACAT1,RPS20,DTYMK,RTRAF,RPL22,SLC25A4,RPL13A,TXN,KPNA6,AR,NONO,TUFM,ATP5F1A,H2BC12,PRPF4,POLDIP2,MBD3,SMC4,RPL4,NPM3,GTF2I,MYL12B,SNRPN,EEF1E1,RPS14,ATG16L1,PSMC4,SAP30BP,RPLP0,LSM2,H2AC7,HSP90B1,TOX4,LMNA,CDK1,MRPS34,SRP14,H2AZ1,TOP1,ARF6,LRRC40,ZMYND11,PSMD7,HSD17B10,H2AC25,ZNF287,SNRPG,EIF3E,RPS13,MRPL22,THRAP3,LSM4,RPL15,EEF1A1,PPIF,LBR,YTHDF2,MTA3,SRP72,MRPL49,ILF2,RPL37A,UBE2S,FAU,SNRPB2,RPL19,MAD2L1,RPL35,RBBP4,RBM15B,RFC5,NOP16,CUL3,RIT1,NOA1,HADHA,UPF3B,SKP1,G3BP2,PSMC1,MYL6,ATP5PO,RPLP1,HP1BP3,XPO5,PCBP4,PHB1,DNM2,ZNF593,RPL7,CCAR2,EIF3D,TRA2A,MRPS35,PRPF19,PSMD3,PRDX1,RPL23,DDX23,COX8A,RPS24,ANP32B,RFC3,SRSF4,MRPS17,G3BP1,TRIM26,TULP3,E2F4,EIF1AX,SF3B5,CTSA,PHAX,CSNK2B,PSPC1,RPP25,RNASEH1,CFL1,CFL2,RPL7A,UBE2H,IGF2BP1,MRPS16,MECP2,RPL27,STK38,RPS15,AGO1,LUC7L3,DYRK2,DDX4,ALYREF,RPL32,MRPS9,SSBP1,MYL12A,RPS27L,MIF,CAND1,GAPDH,PPIL4,LSM3,KPNA1,TAF9,RPL24,H2AC4,CHCHD1,DHX9,RPL17,HNRNPK,MRPS33,PSMA5,H3C1,TP53,RPSA,STRBP,DISC1,DDX42,MRPL13,RPL10,MATR3,SNRPB,PSMD1,HNRNPC,PSMA4,HNRNPAB,MYC,H1-1,RPS26,PSMD14,MRPS25,H2AZ2,CIRBP,CCT2,DDX5,SF3B1,RPS28,PHB2,EEF1G,TRA2B,UFL1,MRPL12,NUFIP2,PABPC1L,YBEY,WDR82,CCT7,HSP90AB1,SNRPA1,SNRPD3,RPS10,XPO1,YWHAG,YWHAH,RPL6,DDX50,AK2,H2BC17,TRIM21,EWSR1,LSM14A,RPL31,CCAR1,RPS4X,RUVBL1,HNRNPF,PSMA2,RPS7,EEF2,NCSTN,TUBA1A,H1-3,ETFB,TRMT1L,RPS23,H2BC1,TUBB4B,RPS12,CMBL,HEXIM2,POP7,CTTN,TUBA1B,ENO1,MRPL53,CCNF,DEK,UBB,SLC25A31,DNAJC8,RPL26,CIAO1,CDC73,PPIH,RPA3,PPM1G,UTP23,LSM8,UBA52,KRT7,RPL26L1,KRR1,ACTA2,RPL12,MRPL24,MRPS23,CDK9,RPL35A,H2AC14,GRSF1,MOV10,BRD3,RPL23A,NKRF,FAF1,RIGI,H2AC6,MRPS18C,CCT5,H2AJ,RPS9,SNRPD1,SNRPD2,ACKR3,ERH,ACTB,TUBB,MRPL23,RPS29,PRPF31,SMARCE1,LSM14B,BAX,RPS5,PFDN2,HSP90AA1,YWHAZ,PSMA3,JADE1,CMAS,YTHDF1,MFAP1,H2AC1,USP39,KRT8,RPLP2,PSMB5,RPL9,RPL8,DHX15,PPIA,HNRNPA1,MRPS26,HNRNPD,SRSF7,MRPS11,FAM76B,HNRNPA2B1,SLC25A5,HSPD1,RPS27A,PSMD12,ATP5F1D,PPP2R1A,RPL29,JUN,ANP32A,SNRPE,SART3,RPS11,RPN1 |
| 1.339e-32 | -73.39 | RIT1 (Ras like without CAAX 1) | protein interactions | 6016 | 1229 | 533 | 19454 | 5460 |
MAD2L2,ERH,STARD7,MRPL23,TUBB,ACTB,SNRPD2,POLR3B,SNRPD1,RPS9,POLR2F,VPS72,PFDN2,VMP1,SENP8,BRCA1,ZCRB1,PMPCA,ATP6V1G1,HSCB,MED11,MRPL57,NOP53,PSMA3,EMG1,MFAP1,PSMB7,USP39,VPS18,SKA2,OR7E24,RGL1,SUPT4H1,DHX15,NUF2,HYPK,ATP6V1A,RPLP2,RPL8,MRTO4,PSMB4,PSMB5,MED4,DICER1,SKIC8,WDR12,ACTL6B,HMGA1,LIPT2,VPS26A,PSMD12,GTF3C3,RPS27A,SACM1L,DHX16,ATP5F1D,PCNA,SRSF7,HSPD1,MAEA,POLR2C,POLR2D,SART3,DOHH,SNRPE,RPN1,BUD23,DPH5,NAA15,UQCRQ,COA5,POLR3H,ENO1,METAP2,TUBA1B,POP7,AP2A1,SMAD2,RPL26,RACGAP1,DNAJC8,DHPS,DAD1,LSM8,UTP23,MRPL20,VPS28,BRIX1,YKT6,NF2,SPCS2,RPA3,SOD1,DCTN6,UBAP1,RARS1,STAMBP,SHOC2,DCTN4,UBE2F,METTL14,UQCRC1,CDK7,LIAS,UBA52,DDAH1,NCBP2,THOC1,MYBL2,PSMB1,TSR2,LDLR,RPL12,SMAD3,CLP1,ANKRD49,GTF2A2,ERCC3,SMN1,ANAPC11,FARSA,NSMCE3,NOC4L,RPL23A,IGF1R,TRAPPC1,POLR2G,GINS4,FCF1,UBE2V1,CMPK1,HINFP,NDUFA2,PSMB6,LRIF1,POLR2B,ALG5,INTS10,PRMT5,GPN2,SMU1,KTI12,DLST,CMTR1,RPS26,RCL1,CCT2,MRPS25,FBXW11,PSMD14,BTF3,CFAP161,CPSF2,MYC,COX6B1,HNRNPAB,PSMA4,HNRNPC,GINS3,SLC31A1,SRSF2,PHB2,SF3B1,DR1,TRMT112,MRPL12,TOMM22,ATP6V1C1,TIMM10,PSMB3,TRMT61A,CCT7,NOB1,ISG20L2,RPS10,DBR1,OSBP,SNRPD3,WDR82,DDX1,MAGOH,XPO1,PFDN5,RPL6,RPS4X,PSMA2,RUVBL1,RPL31,LTO1,ABCF1,TAF10,RPS23,HGS,LSM10,EEF2,RPS7,DHX38,CDC20,ROMO1,UBA3,RSL24D1,IRF2BP1,PHAX,CSNK2B,SEC61A1,SRP54,PTPMT1,CDIPT,UQCRC2,ALG2,EXOSC1,DTL,UBE2H,MRPS16,CHCHD4,PSMB2,CARS1,CCNB1,RPL7A,GRPEL1,UGP2,DNLZ,WDR3,RPS15,ELOF1,LSM12,DPH3,DPAGT1,GFM1,DDX46,RPL27,NLE1,SEPHS2,LUC7L3,SYS1,GTF2H4,NDUFA1,METAP1,UBE2N,RPL32,ALYREF,LSM3,NOL12,NUS1,ATP6V1D,TRMT5,MED27,DOLK,RPL24,PPIL4,GAPDH,MEPCE,RPL17,NEDD8,PSMA5,CSE1L,HNRNPK,DHX9,RAD1,FURIN,BIRC5,DDX42,ESS2,GNPNAT1,IMP3,RPSA,TP53,CENPM,GGPS1,RPL19,TNPO3,RPL7L1,RBBP4,RPL35,UMPS,RPL37A,FAU,RIT1,PFDN6,RIOK2,TOMM40,RFC5,RHEB,GALE,MCM3,RRN3,NOP16,CFAP20,GPR17,POLA2,PSMC1,SKP1,PTN,MCMBP,NUBP2,THOC3,ATP5PO,PPP1CB,SUPT3H,TIMM13,RPE,ETF1,WDR77,NOP58,POLR3F,RPL7,BUD31,IGBP1,XPO5,COPS2,DNM2,PHB1,DDX23,PSMD3,MARCHF5,DPY30,MRPS35,PPWD1,MCM6,RFC3,RFC2,ATP6V0B,RPS24,PPAN,SF3B5,GNB1L,EIF1AX,AP2S1,VPS33A,CCS,MAK16,GFPT1,GTF2E2,TECR,MAGOHB,TXN,DTYMK,CFAP298,RPS20,UBE2I,EIF4A3,FXN,ATP5F1A,TUFM,GMPS,KPNA6,CDC16,SEC13,NHP2,RPL4,USP8,SMC4,GPX4,PRPF4,RPLP0,NOL7,TTI2,ZNF574,IFRD1,CDK1,PTP4A2,HSP90B1,LSM2,ELP3,WDR83,CPSF4,RPS14,PSMC4,CCND1,TPT1,G6PD,ARF6,EIF2B5,POLR2I,EIF2B2,PWP2,SRP14,SSU72,TOPBP1,MPHOSPH10,PSMD7,GTF2E1,PET117,ORC5,TMEM199,CGB8,GMPPB,ARF4,RPS13,EIF3E,PAK1IP1,LSM4,HSPE1,SEPTIN7,SNAP23,EMC2,ILF2,PPP4C,HOXD12,DMAP1,EEF1A1,THAP1,RPL15,POP5,BCS1L,PHF23,MRPL11,ATP6AP2,PSMD4,SNRNP40,PSMD6,SF3B4,ANAPC2,MCAT,POLR1B,ARMC7,FTSJ3,HMGCS1,RPL39,COX11,TBCE,SAP18,COX17,YAF2,DPH6,XRCC5,MRPS18A,RPP21,NUP62,RPL27A,PAFAH1B1,GOSR2,PGS1,EIF2S1,TCP1,LSM5,DYNC1I2,POLR2L,SRSF1,PPP1R11,UTP6,CENPW,RPL28,RPAP3,RUVBL2,RABGGTB,RTCB,SDHC,KLHL12,RPL18,TMEM182,SMNDC1,CSTF3,PPP1R10,SMURF1,BCCIP,SRPK2,BUB3,MRPS21,PPAT,MOB4,EIF2S2,RPS3,PSMA6,ATP1A1,PSMG3,LSM6,RPS17,ANAPC15,NCAPG2,RPF2,NAA50,MAT2A,PTPN11,CEP85,EIF4E,TOMM20,MARS1,HSPA5,MRPL41,RBM22,H2AC13,EXOSC4,RNF113A,POLD2,HEXIM1,UTP15,ACACA,RPA2,QRSL1,H2BC11,RPRD1B,EIF2B3,MRPL10,NDUFAB1,PPP1R8,PRELID1,DKC1,CDC5L,RPS16,MCL1,TRAPPC3,GTF2B,SDHB,COX4I1,CDK12,RPS2,RPL10A,PSMG2,SNRNP70,COPS5,RIT2,KARS1,PGAM1,CAMKV,IMP4,RPL3,STX18,ABCE1,THG1L,SNAPC2,TAF2,RNF8,TFRC,IK,MAD2L1BP,NFE2L2,ACTR1A,WBP11,GLRX5,PREB,RRM1,CDK4 |
| 3.182e-32 | -72.53 | UBE2M (ubiquitin conjugating enzyme E2 M) | protein interactions | 9040 | 636 | 317 | 19454 | 5460 |
PRDX3,WDR77,ARCN1,MYL6,SLC25A3,RNF7,ISOC1,PSMB7,DCTN3,HADHA,PSMA3,NUP50,PRKD3,THOC3,FBXO30,SKP1,PSMC1,SRM,MCM3,MCM4,PRPF31,CUL2,CUL3,CDC123,PFDN2,HSP90AA1,YWHAZ,LMNB1,SENP8,RPS9,SNRPD1,SNRPD2,RAN,EIF3K,ARF1,ERH,UBE2V2,B4GALT3,ACTB,TAB1,SPINDOC,RBBP4,TUBB,PRDX2,DCUN1D3,ACTN4,PPP2R1A,TXNRD1,KHDC4,B3GNT2,ANP32A,SNRPE,STK16,RPS11,GDI2,RPN1,VAMP2,EZH2,BAG2,PCNA,SLC39A7,HNRNPA2B1,SLC25A5,ZYX,HSPD1,COPS4,RPS27A,MCM6,PSMD12,KCTD17,ATP5F1D,G3BP1,RBBP7,EIF3D,PSMD3,PDIA3,PRDX1,COTL1,DCAF11,TST,HNRNPD,AHSA1,PPM1B,COPS2,RPLP2,TYMS,PSMB5,PSMB4,RPL8,PPIA,KCTD10,SPTAN1,COPS7B,EIF3J,UBLCP1,SEC22B,RPS14,PSMC4,RARS1,HSP90B1,LMNA,GPX4,MIS12,DCTN6,SOD1,RPA3,PPM1G,RPL4,PDHB,NONO,GMPS,USP14,RPL26,FBXO7,ATP5F1A,STK38L,MAPRE1,CA2,CCDC22,IVNS1ABP,CHORDC1,RPS12,POLR3H,ACAT1,RPS20,ODR4,CMBL,CTTN,TUBA1B,ENO1,STUB1,CCNF,TXN,COPE,LDHA,CD2BP2,EEF1A1,CCT5,RAD23B,SRP72,TRAPPC13,KLHL26,AP1S2,HSD17B10,IGF1R,HAPSTR1,CPNE2,RAB1A,PTGES3,EIF3E,PRDX4,HSPE1,HUWE1,PCED1A,HDAC6,ISYNA1,KLHL9,CALR,DNAJC7,PSMD7,CRBN,NME2,PSMB1,ACTA2,SRPRA,MDM2,DCUN1D1,NEK7,LAP3,EIF4B,CTBP1,ADSS2,EP300,GPHN,HSPA8,XRCC5,PEBP1,DDX39B,PHB2,EEF1G,SNRPB,BAG3,PSMD1,PSMA4,LDHB,HNRNPAB,MYC,COPS7A,MDH1,DNAJB6,KIF3C,CYP1A1,CKB,CCT2,PRMT5,NFKBIA,ACAP2,ESR2,KBTBD6,PSMB6,PSMD6,PSMD4,ATP5F1B,RPS7,EEF2,SOX2,H1-3,PTS,RANBP1,DCUN1D5,RHOBTB1,CRKL,KLHL12,ZRANB2,PDHA1,PLS3,TUBB4B,PDIA6,RTCB,TRIM21,EWSR1,RUVBL2,CCT8,FBXO3,TFG,PAX6,RPS4X,RUVBL1,KRAS,DCP2,HNRNPF,PSMA2,YWHAG,YWHAH,YWHAB,CBL,AGR2,FKBP4,AK2,EED,CCT7,HSP90AB1,SNRPD3,SUMO3,TCP1,RAB1B,UBE2M,GSTP1,HEXIM1,HBB,RPA2,PRDX6,TNFAIP1,PGK1,BAP1,HSPA5,GRPEL1,STK38,CFL1,RPL7A,PSMB2,MAT2A,UBE2H,OAT,UHMK1,MARCHF3,ATP1A1,DTL,CHCHD4,BICD2,EIF3G,PSMC5,B4GALT1,PSMA6,RPS3,UBA3,ROCK1,SMURF1,ADRM1,ACTR1A,TP53,RPSA,KBTBD4,PSMC3,TAB2,CRABP2,SLC16A1,RPL3,KLHL24,NAE1,MAP1B,CAPZA1,RPL17,MEPCE,HNRNPK,SRPRB,CSE1L,KPNA2,PSMA5,NEDD8,H3C1,ELOC,KLHL22,GAPDH,COPS5,PGAM1,MAP4,USP15,RPS2,KPNA1,RPL24,EEF1B2,SYNCRIP,CDC5L,CAND1,CPNE1,KCTD3 |
| 1.423e-31 | -71.03 | BRD4 (bromodomain containing 4) | protein interactions | 23476 | 1601 | 657 | 19454 | 5460 |
TP53,RPSA,CAPN2,CBX3,DDX42,DHX9,ZNF451,PSME1,POLE4,MEPCE,RPL17,PSMA5,H3C1,NEDD8,HNRNPK,SCML1,CSE1L,PPIL4,ELOC,GAPDH,API5,EDC3,ENY2,TAF9,MAP4,MED27,RPL24,H2AC4,SMCHD1,IL17F,MED29,DSTN,NT5DC1,SSBP1,ALYREF,RPL32,UBE2N,ESD,KMT5B,CAND1,CPNE1,CDC42,PGK1,DDX46,RPL27,PML,TXNDC17,NBN,WDR55,RPS15,WDR3,HDAC3,STK38,CFL1,SMARCA5,PSMB2,RPL7A,CDKN2AIP,SORD,MECP2,UBE2E3,SRP54,CSNK2B,PHAX,MACROH2A1,PSPC1,UQCRC2,IRF2BP1,EIF4H,EGLN2,H1-3,RPS7,EEF2,TRMT1L,DHX38,SMARCB1,RPS23,TAF10,TUBB4B,CDK5,EWSR1,TRIM21,RPL31,ABCF1,CCAR1,RPS4X,PSMA1,HNRNPF,PSMA2,RUVBL1,XPO1,YWHAH,BTF3L4,CTNNB1,DDX50,BAZ1B,IFI16,RPL6,CDC23,DDX1,UBFD1,WDR82,PSME2,SIN3A,FUBP3,ANXA4,CCT7,HSP90AB1,RPS10,HNRNPL,ZNF740,SUMO3,SNRPD3,SUMO2,PTAR1,ACSS2,PSMB3,ZC3H14,NUFIP2,EIF4B,CNDP2,TRMT112,CSNK1A1,MED31,MAP2K1,SF3B1,DDX5,PCGF2,MED13L,PEBP1,DDX39B,GINS3,FXR2,TRA2B,SRSF2,NDUFS2,UFL1,PHB2,EEF1G,KANSL3,BTF3,SNRPB,CPSF2,UFD1,CREBBP,MYC,LDHB,PSMA4,PRMT6,HNRNPC,HNRNPAB,RPS26,MDH1,SERPINH1,ADK,CCT2,S100A11,PSMD14,ATG3,CYP1A1,H2AZ2,SMU1,PRMT5,VDAC2,CBX5,PSMB6,POLR2B,APEX1,ESR2,STAT1,MATR3,CD2BP2,MAP2K3,AURKAIP1,SOX9,CMPK1,CCT5,GBE1,POLR2G,GINS4,NDUFS3,RPL23A,SFXN1,PQBP1,NKRF,TCOF1,VPS16,HUWE1,TSSC4,TRIM63,NSMCE3,FARSA,VRK1,H2AC14,ERCC3,SETD5,BRD3,UQCR11,TES,PSMB1,RB1,RPL12,NHEJ1,CDK9,NCBP2,MRPL24,RPL35A,HTRA1,THOC1,UQCRC1,MED30,CCNA2,CDK7,UBLCP1,SF3A1,HNRNPH3,METTL14,PPIH,TCEA1,HELLS,PPM1G,RPA3,PRIM2,PIAS1,BRIX1,DNAJC8,ZNF687,CDC73,MAPRE1,PPIG,MSN,CTTN,EIF2AK2,ENO1,UBE2L3,PDCD5,DEK,JUNB,VIRMA,PPP2R1A,RPL29,JUN,RBM12,ANP32A,RPS11,POLR2D,POLR2C,JPT2,SART3,PPID,GDI2,PCNA,SRSF7,BAG2,SLC25A5,HSPD1,SCYL2,HNRNPA2B1,GTF3C3,RPS27A,UBE2A,RAD21,COPS4,SSRP1,ZNF592,UFM1,DHX16,HNRNPA1,HMGA1,MED4,HAX1,HNRNPD,COTL1,WDR12,SKIC8,PPM1B,ATP6V1A,BRD9,RPL9,RPL8,PSMB5,PSMB4,EGLN3,DHX15,INA,SNX18,ACTL6A,SPDYE4,IRF2BPL,MFAP1,ANXA7,FKBP1A,SLC25A3,USP39,PSMB7,TXNL1,EMG1,PSMA3,CFDP1,PYGB,CMAS,MED11,UCHL3,SRI,NOP53,SRM,PRPF31,SMARCE1,CAPG,ATF1,RPS5,HSP90AA1,MED10,YWHAZ,BRCA1,POLR3B,RPS9,S100A6,MAT2B,ERH,USP5,PRRC2A,LGALS3,TAB1,MED17,TUBB,WBP11,NAA35,MRPL47,PSMC3,TAF2,PHC1,CHAMP1,TFCP2,TFRC,IK,ABCE1,RPL3,NAE1,NOSIP,SLC25A11,MNAT1,CAMKV,KPNA2,COPS5,CSNK2A1,KARS1,RBM17,PGAM1,RPS2,CDK12,RPL10A,PSMG2,POLB,SNRNP70,NOS1AP,AKR1B1,SYNCRIP,GTF2B,AIP,EEF1B2,COMT,TMPO,DKC1,SURF6,CDC5L,RPS16,GTF3C4,CCNH,NTPCR,CAPN1,PPP1R8,SUMO1,UBE2M,GSTP1,HEXIM1,H2BC11,RPRD1B,RPA2,ZNF326,CWF19L1,HNRNPH2,PRDX6,THUMPD1,BANF1,POLD2,HSPA5,KDM1A,UBE2K,MRPL41,SPMIP10,RPS17,RPF2,MAT2A,MED22,SUB1,PTPN11,ATP1A1,CALU,EIF3G,SPOP,QSER1,EIF2S2,CREB1,RPS3,PSMA6,LIG3,UBN1,PAFAH1B3,PPP1R10,ROCK1,CSTF3,BCCIP,BUB3,KCTD9,ADRM1,CSTF2T,KIF2A,TOP3B,SUPT5H,MED9,MTA2,ZRANB2,RPL18,SMNDC1,DNAJB4,RUVBL2,TRIM11,PABPC1,RBM3,TOP2B,CCT8,RPL28,CDCA7L,MAGEC2,POLDIP3,HNRNPDL,HMGN4,HSPB1,FKBP4,EED,FABP5,SRSF1,POLR2L,HMG20A,EIF2S1,LYAR,TRIR,TCP1,RPL27A,NCOA5,PAK2,CTBP1,ADSS2,HSPA8,EP300,RFC4,SNRPA,PYM1,XRCC5,FAM50B,SAP18,HNRNPA0,STAU1,PAPOLA,NSA2,DNAJB6,H1-10,CHTOP,RBM27,FTSJ3,SF3B4,PHF21A,GTF2F2,GTF2F1,ZHX3,EFHD2,PSMD4,ATP5F1B,SNRNP40,EEF1A1,RPL15,IRGQ,MTA3,AKR1C1,PHF23,ILF2,PPP4C,RAD23B,DMAP1,ZC3H11A,SEPTIN7,RING1,HINT1,RPS13,RNF20,CTNND1,OLA1,MSH6,SNRPG,MDC1,LSM4,PAK1IP1,CTNNBL1,THRAP3,GTF2E1,ZMYND11,TLE1,DNAJC7,MED21,PWP2,ETV6,SSU72,H2AZ1,SRP14,DFFA,UBP1,POLE3,CAV1,G6PD,POLR2I,TOP1,EDF1,EIF3J,RPS14,PSMC4,TPT1,CCND1,OXSR1,RPLP0,MACROH2A2,LMNA,CDK1,HSP90B1,H2BC12,PRPF4,CSTB,SIRT7,MBD3,AATF,EIF5B,GTF2I,NUCKS1,SMC4,HMGB1,RPL4,ATP5F1A,NONO,AR,GMPS,TUFM,USP14,CDC16,TADA3,DCAF16,PIP4K2C,RTRAF,GANAB,ACAT1,UBE2I,PTEN,RPS20,PELP1,STUB1,EIF4A3,LDHA,RPL13A,NUP153,GFPT1,SAP30,GTF2E2,TXNRD1,E2F4,RNF126,VPS33A,EZH2,UBE3A,RPS24,MORC2,ARGLU1,PPAN,MCM6,PPWD1,ANP32B,RFC2,RFC3,G3BP1,LASP1,RBBP7,ATG7,EIF3D,TRA2A,PSMD3,PRPF19,TAF7,PRDX1,DPY30,AHSA1,RPL23,NQO1,DDX23,KDM2A,XPO5,COPS2,HP1BP3,DNM2,CBFB,THOC2,PHB1,CACYBP,CETN2,LRWD1,NOP58,POLR3F,ATXN10,SPTAN1,RPL7,CCAR2,PPP1CB,ETF1,WDR77,H1-5,MYL6,RTF2,MED23,ATP5PO,ADNP,HADHA,NUP50,CLDN1,PSMC1,POLA2,UNC45A,MCMBP,RNF40,RFC5,PROX1,MCM3,MCM4,USP13,CUL2,CUL3,POLD4,BLVRA,LMNB1,WDR20,CDC7,AP2M1,CPSF1,RAN,UBE2S,MAD2L1,RPL19,AKR1C2,RBBP4,RPL35,RPL7L1 |
| 2.215e-31 | -70.58 | negative regulation of cellular process | biological process | GO:0048523 | 5320 | 1896 | 18204 | 5365 |
IFT57,TCTA,SNX3,WWP1,MIR208A,PKIG,GFI1,ZMYM2,CNKSR3,RUNX1,ZMPSTE24,HBEGF,ZBTB42,AP2A1,LILRB4,RPS27L,ARB2A,ARL6IP5,ZGLP1,S100A11,SMG5,RC3H2,ACHE,PFDN6,TRIM11,MEF2C,BEND5,MSTN,CAV3,LYPLAL1,TNFAIP8,FKBP1B,ERLIN1,VGLL4,TAX1BP1,CD28,PTPRZ1,HSP90AB1,CBFB,HTR2A,INPP5K,KLF9,APLN,PELI3,MOV10,CD83,PSRC1,MIR190B,CDK5R1,MAGED2,H2AC13,DAD1,SOCS4,SMAD5,TGIF2,USP15,GLO1,THOC2,WWP2,HNRNPA1,MIR216B,FMO2,PEG10,ZNF207,G3BP1,HSPB2,MIR556,APOBEC3G,ZFAND6,PTGES,TDRD7,PRDX3,SNCB,FRMD8,CREB1,TMSB10,IER3,CTNNA1,FZD3,TNR,BAZ1B,GPX4,TADA3,CIRBP,CCL21,MIR20A,MAFG,IFI35,TMOD2,MACROH2A1,RIT2,TMEM170B,MIR708,NABP1,PFDN2,ATP2B4,USP14,MAD2L1,RAP1B,ZNF174,SHC1,CHGA,CTBP1,PRKCB,FMO1,C1QC,HSBP1,IRF2,RAP2B,TRIM37,TMEM115,SOX2,PTPN22,TOM1L2,MTDH,ADTRP,GREM1,MIR940,VPS4B,CDH13,PIWIL2,SNX33,CRYBA1,TGFB2,CHP1,MIR144,DBNDD1,NOTCH2,SVIP,SPRED2,ZBTB38,MXD1,RING1,SEC22B,PCNA,ATP5F1B,MIR612,JUP,GPNMB,MIR711,TSPO,ZBTB6,BTG2,RNF20,RAP2A,TMOD1,DCP2,STK24,PDE9A,MIR626,PTGER4,CSNK1A1,SFRP4,RPL23,MIDEAS,CYP7A1,TGFB1I1,GAPDH,MIR934,CNOT7,RAD21,LSM6,CLN8,SLC6A4,TPBG,EZH1,MTRNR2L7,MIR1262,IL7,OSBPL8,TPRA1,ESR2,FZD6,PYCR1,CAPG,PIWIL4,SCAMP5,MIR155HG,VASH1,ATXN1L,FGFR1,PTPRQ,HELT,AZGP1,GHITM,NONO,CDK6,TRIM27,DHRS3,CEP97,CCL11,ENC1,PTPN11,HUWE1,IDO1,PFDN1,DIPK2A,TAF7,MIR34A,VPS4A,MIR609,IL13,VPS72,MITF,ZNF451,MIR216A,AIPL1,STK38L,XAF1,LDB1,DIS3L,TFDP2,DDR1,UFM1,MIR657,ACOT8,MIR1277,RHOH,MIR581,CGGBP1,MIRLET7C,SPHK2,ATG3,TNFRSF14,CXCL10,PSMD10,CFDP1,ATAD1,MIR424,OGG1,NKIRAS2,FBXW11,RAG1,SPINDOC,H2AX,EPHA2,MIR495,CORO1C,CXXC5,MIR361,ZNF304,MIR23A,STXBP6,AGER,RHOB,CAB39,YAF2,MIR567,H2AZ1,ROCK2,LBH,ADIPOQ,FOXP4,ETF1,RPS3,TRIM6,NMBR,FBXO31,TRAF2,CBX5,TIA1,RGCC,LST1,MIR651,ABCC2,RGS10,RTN4,MIR548C,INHA,CD9,MIR30B,HADH,MIR519D,LILRA2,MIR375,MSX2,BCL2A1,RRAGB,CHMP2A,LYAR,SIN3A,RERG,MIR33B,MIR197,POU5F1,RMI2,ZNF592,MIR210,SNAPIN,MIR593,HSPD1,MIR885,CBX3,VDAC1,MORC2,OVGP1,JUN,GPR37L1,MTA3,TMEM196,MIR449A,PCBP4,MIR185,UBE3A,IL12B,FOXP1,PEA15,MIR190A,PCDH17,MIR107,USP2,RSAD2,MIR1-2,MIR206,H2AC4,MIR643,AATF,ADRB3,HTRA1,SNX12,TRIM24,CRKL,CDK12,ARRDC3,CTDSP1,PHF21A,PKIB,MIR573,BST2,TSPAN15,BCL2L1,MAF1,STXBP1,LIMS2,DEDD,B4GALT7,AKR1A1,GSK3A,PPP1R8,MIOS,TBC1D4,MIR136,STARD13,DPH3,LMNA,ZMYND11,GMNN,GRB10,TANK,SELENOS,CEND1,DRD3,MIR9-3,LZTFL1,SDHAF2,PRMT5,MIR99A,H2AC6,MIR92B,WDR77,PIK3R3,OVOL1,BOK,EP300,VDAC2,ANXA7,GPX1,BACH1,NPR2,IRF1,ITM2B,DNAJC5,INSM2,BPIFB1,SHOC2,CGRRF1,CTNNBIP1,METTL14,TCEAL7,NBN,IFI16,TLCD3B,DDAH2,MIR551A,LMO3,NTRK2,TFIP11,MIR181C,NDC80,MECP2,MIRLET7I,MIR29A,BNIP3L,EDC3,MIR542,LYPLA1,EXOSC3,ADGRG1,BMPR2,ADRA1A,SRC,MIR34C,CDK20,ANGPT1,PPID,FAIM,XPNPEP1,MTMR2,NRDE2,SRGN,ATF4,HNRNPK,HEXIM1,PLCB2,IFNG,TAB2,BIRC5,CAMSAP2,TENT2,ZBTB5,DTL,MIR135B,USP30,LGR4,MEF2A,PRKRA,OAZ3,POU3F4,TRAF6,CCNF,NAE1,MIR222,NUDT12,THBD,MIR181D,MIR1180,MIR802,TRIB1,MIR378A,TMEM59,PLAGL1,CCL19,SOSTDC1,IRF2BPL,PSPC1,MIR937,P3H1,ARG2,TESK1,LRIF1,NFKB1,MIR599,MIR924,PCGF3,KLF10,MIR205,SETD5,MIR653,STAP1,AKR1B1,ATF3,FCGR2B,SMAD3,ISCU,MIR24-1,DUSP22,SLC7A11,SCML2,TRIM62,IRF2BP1,TMIGD3,RHBDD3,CRHBP,TAF9,HNRNPD,CCN3,TEX19,EIF4A3,MIR662,MIR504,IL4,MDC1,THAP1,SCML1,DGCR8,NKRF,MIR146A,FXN,CHID1,MIR101-2,CPTP,LANCL2,MIR150,GPR35,RUVBL2,DKK3,AP2M1,ING2,EFNA5,MIR452,SWAP70,IL12A,BCL10,MIR132,HNF1B,MIF,OPRM1,RNF34,KLF12,MIR1225,STK3,CFL1,PARD6A,HEY2,IRF3,MAP3K12,DYRK2,RPS14,TLR3,UBAC2,MIR3173,RORB,SPEF1,CST3,CCL5,RGS19,KCNB1,FZR1,SOCS2,DUSP19,NUPR1,AGO1,CRYAB,MIR761,MIR484,MIR302B,FLCN,ARFIP1,ERO1A,BAG3,NDFIP1,CBL,SOX9,DHRS7B,PAEP,CSNK2A1,CPEB1,GHRL,BRINP3,IFRD1,DCAF5,DLG3,SNAI2,MIR489,MIR339,CDC5L,TRIM29,PRPF19,PELO,ING5,NR1I2,CD200R1,EIF4EBP2,CTTNBP2NL,FKBP1A,TMEM176A,MIR558,SAP30L,IRF8,CCR1,MIR600,DKK1,SPOCK1,VAMP8,TMEM182,MIR367,RFLNA,GAS8,C9orf72,HAND2,MBD3,SRSF7,ADRB2,DDX4,SEMA5A,CCR7,RNF8,STAT6,DUSP3,MAP2K3,MIR192,LRP3,KLHL15,DPEP1,SHISA2,MIR9-1,LSM2,OTUD7B,JAGN1,ADD1,SESN3,RERE,NAA35,MIR218-2,MIR193B,HOMER3,CDKN1B,TP53TG5,RBM15B,UFL1,CXCL13,RETREG1,CHMP4C,SCFD1,CYP27B1,TRIM15,ZBTB14,MIR335,LGALS3,ZNF692,WDR6,MIR1249,DROSHA,MIR198,PIWIL1,MIR195,PTPN1,HSPA8,ACKR3,TIMP4,JADE1,CER1,DLG4,IFI6,PAX9,MIR147A,CRBN,MIR583,CDK2AP2,TP53,HENMT1,SDCBP,API5,MIR188,MDM2,NCBP2,DDX5,MIR1-1,NLRP3,CCL25,CASTOR2,ZHX3,PPM1D,MIR214,H2AB1,MIR502,YWHAB,PDCD1LG2,CSNK2B,MIR552,CLDN3,ARF6,CASC3,H1-5,IRF4,MIR105-1,MIR16-2,CDKN1A,MDFI,SUPT5H,TENT5C,LSM14A,ZNF365,TNFAIP1,WDR44,NPY5R,NLRP2,MIR301A,RNF152,ILK,EID2,ZNF655,MIR615,CXCL12,PLAC8,CDK5,HEXIM2,STUB1,DNAJC10,PKIA,CHRDL1,DUSP10,MIR628,KDM2A,MIR98,HECW1,MIR649,RNF5,CX3CL1,MIR1298,PPT1,MUL1,NDUFAF2,CAMK2N1,MID1IP1,ING1,RPA2,ERLEC1,PHB1,MIR624,ZNF24,MIR148A,ZBTB16,MIR383,SH2D1A,IFNK,HDAC3,MIR96,MIR648,NACC2,SFN,DNAJB6,SYT4,AQP11,MIR577,SAR1B,WNT10B,TXNIP,PAX6,SLC35C1,MIR887,TP53INP2,MIR454,HHIP,OPTN,HP,BABAM1,FOXP3,CD274,AKT3,MIR1224,PPP2CB,ACTL6A,SMARCE1,KLHL25,HAX1,SPRY1,LMNB1,CLIP3,MOSMO,MMP14,GNRH1,MAGEC2,MACIR,LRRTM1,BAHD1,ASPM,CHMP1A,PADI2,GNAO1,ZBTB2,EIF4E,TP53INP1,ID4,PID1,XBP1,RPL13A,PFDN4,BUB3,TERC,AR,SOD1,MIR492,CNR1,TSC22D3,HIRA,CCND1,PAIP2,CAAP1,IL2,MIRLET7B,PAK2,MIR130A,TRIM63,ACP5,B4GALT1,MIR125A,CCL28,NRP1,MIR187,PCSK9,RPGRIP1L,TCEAL1,PPP3R2,PHC1,RGMA,PARL,MIR10B,GLCE,PRKCE,MIR450B,SIAH2,TGFB3,MIR374A,WNT7A,RPL26,GPC1,SLC25A31,SERTAD2,DUSP26,TCF23,MIR331,SIRT7,TAX1BP3,PIP4P2,SAP30,NFKBIA,PPP1R11,BRD9,SPRED1,KICS2,MIR877,MIR345,RGS5,BAK1,VDR,TCAF2,MAP1B,MIR301B,OSM,YWHAZ,PRKACB,MIR944,PIK3R2,TNFRSF9,RXFP2,STMN2,NDUFAF4,SOX14,FZD4,AREL1,EIF3E,VSTM2L,FGF23,PRELID1,NUDT16,CARD19,PPM1B,NSMCE3,TIMP1,SAMHD1,SATB1,IL23A,MTA2,CTSA,VEGFA,TMEM176B,H1-3,CCDC85B,RB1CC1,KLF3,THY1,MIR939,MIR140,PDE4B,CD40LG,TNFAIP8L1,RNF41,ICAM1,SPTAN1,NTF4,APEX1,TCIM,RGS7BP,NLGN1,PIK3CA,CD47,CDSN,MIR15A,ROCK1,SUPT4H1,MIR373,H2AC1,G6PD,MYLIP,APOBEC3A,C1D,XRCC5,TBK1,CYRIB,MIR32,FEZ1,MIR632,ZBTB39,DPP4,PIAS1,VPS54,VAMP3,POU1F1,RBM42,CIART,PDE2A,IGF2BP1,NPPC,PSMC5,SEMG2,PHF23,CCL2,DUSP6,SERTAD3,TXNDC12,HNRNPL,NUF2,APOBEC3C,MIR129-2,MALSU1,FBXW7,EAF2,PRR5L,NOG,TESC,CERS2,MIR101-1,NAIF1,VSIR,MIR363,KBTBD6,LAMP3,CNOT6L,RASD1,GPR171,RAB33B,GPAM,TRIM32,TMOD3,MAGEA4,SMAD2,MIR342,MIR31,BRCA1,CYP2D6,PTN,RNF113A,MTM1,PSEN1,TNKS2,UBE2I,APOBEC3F,SNRNP70,ZHX1,MIR324,TNKS,RBFOX2,MEPCE,CAV1,IFNB1,MCOLN1,PRDX4,RBBP8,SOCS3,ST3GAL1,CDKN2D,PIM2,AGAP2,DDT,OSR2,RPS6KA4,MIR194-1,CDK1,SNIP1,PDCD5,CYP26A1,MIR105-2,APOBEC3D,CTDSP2,GDI2,MIR557,BTF3,NFIL3,EED,GLRA1,HCRT,LRRC14,DLX1,MIR106B,CASK,SLC43A2,ITM2A,CDC20,DAPK1,MIR142,MIR490,HSPB1,MIR184,MYC,MIR126,MIR553,OGN,CTNNA2,TRIM22,ARHGAP25,MIR656,LITAF,PICALM,ATP1A2,PYM1,ADAMTS20,SLC35F6,ACTN4,MIR1260B,CAV2,ZBTB26,XPO5,SMAD1,MIR200C,MIR425,IRF7,H2BC11,NLRP6,COPS5,SUMO1,OAS1,TWIST2,CRHR1,HNRNPC,RNF126,LTA,GSTM2,FABP7,DYRK1A,GCLC,WASL,CEACAM5,PROX1,TNFSF18,CREBBP,MIR147B,ZBTB18,ZNF177,MIR152,DDIT4,IL1A,PAK1IP1,KRAS,ADAMTS1,NCK1,IRF6,FGF10,SPC24,SESN2,MIR106A,SLA2,PRKCQ,PGR,UFD1,F11R,MIR193A,CCDC22,FATE1,PAQR3,MIR30A,PPARG,IKBKB,MIR422A,EGR1,MKKS,MNAT1,NR4A2,AP1AR,MIR28,FSTL1,PTGDS,EPO,EZH2,UPF3B,MIR554,ADCK1,CHRNA7,YTHDF2,LEMD3,MIRLET7G,ADORA1,ADORA3,NKIRAS1,SIX5,NKAP,MIR340,P2RY1,PRDX2,MIR586,DNAJC2,POLE3,DDIT3,EYA3,SMG9,TOMM70,MIR590,CCL8,ARF1,LCMT1,CLIC4,SVBP,CTSC,FKBP8,MIR133B,RGS1,RRAGA,CXCL8,LPAR1,UBE2D3,ATG101,ITGA6,MIR770,CYGB,GPR173,AZI2,EIF4E2,ACVR1,LMAN1,PRKCA,NEFL,RNF144B,BCL7C,PLSCR1,CDH11,PIP4K2C,F2,CCR2,HSP90B1,HAPSTR1,APOBEC3B,INPPL1,DAP,CGAS,STRADB,ADNP,CTTN,ASIC2,ZBTB45,MPIG6B,LBX1,RGS2,HMGB1,BCL7B,ABHD17A,DFFA,PYCARD,HRAS,MIR875,TRIM46,GABPA,SLC39A10,RAF1,SRSF2,STN1,PTGFR,MIR611,MIR640,IL10,FERD3L,DDRGK1,MIR636,MIR505,NAA15,RBBP7,CRLF3,PPP1R1B,TAGLN3,NKX6-2,CDKN2C,MIR145,CX3CR1,MSX1,PEBP1,MAEA,SYNCRIP,NGDN,GPRASP3,UBE2B,HACD3,DNM2,SMURF1,GNAZ,MIR330,MIR21,FGFBP1,CPNE1,ANAPC2,WDR82,SERPINB9,PC,IFI27,HYPK,SRSF10,NDUFS3,DXO,TCF21,FOXD3,LDOC1,BAP1,CD36,TPT1,MIR129-1,ENO1,LDLR,AURKAIP1,DMAP1,PRL,MIR186,PELI1,PPARA,PAK5,MAP4,VEGFC,MIR10A,ZNF263,NEUROD2,LDB2,FGR,BRAP,THRAP3,YWHAG,BTG1,CRMP1,STAMBP,ERP29,ABHD6,RFX5,CSK,MIR633,EIF2AK2,GNAI2,CREBZF,MIR377,LMO4,GRIA1,RRN3,MIR497,UBE2N,SLC8A1,CARTPT,NCOA5,SS18,NUP153,STK26,MIR221,MIR155,ATP5IF1,STAT1,USP3,LRP6,MED31,MIR500A,PTEN,JAK2,MCPH1,DEFB114,CD34,SMCHD1,TMEM215,CRY1,NOP53,ASZ1,NDNF,MIR938,MIR1271,EID2B,UBE2G2,MIR578,SMAD4,RNF128,LSM4,NAA16,CD164,PACSIN3,MIR384,DR1,SNX5,MAGOH,PDCD10,TSNAX,H2AC7,SP2,SLC1A1,CTNNB1,SHLD1,HYAL2,MIR1227,BRMS1,TRIM3,GSTO1,MIR625,GTF2IRD1,MIR100,EIF4EBP3,MIR153-1,MIR296,MYT1L,CIPC,TLR8,NTRK3,CCDC3,MIR563,MIR618,BMPR1A,IVNS1ABP,SMARCB1,PRMT6,FBXO7,SOX3,NFE2L2,DNAJB4,UBASH3B,LPXN,SRSF4,MIR549A,DRAP1,EI24,SH3BP4,DAG1,PIWIL3,SMARCA5,MGARP,MMP28,KCNJ11,MIR765,SST,NME1,WIF1,MIR601,KRIT1,CD200,EPS8,SQSTM1,LEP,POLR2G,ZNF175,PHB2,MIR148B,CBLL1,FGL2,MIR7-3,GNB1L,MIR34B,DYNLL1,MIR873,HOXB8,GADD45A,CAMK2N2,ZBTB25,FKTN,NEK2,CD2AP,CD38,PLN,GSKIP,CTLA4,GRM2,H2AZ2,SFTPD,PML,BMPR1B,HCLS1,UBXN2B,PABPC1,SRI,FGF13,EIF2S1,IL15RA,MIR491,SNAI3,TERT,CRADD,MIR141,CISH,MACROH2A2,MINAR1,CCL23,MIR23B,CLU,RINT1,TMIGD1,ADIPOR1,STK38,NFKBIL1,NKX3-1,NR2F6,STC1,SARM1,MAGEB10,LMBR1L,ELOC,DDIT4L,TFRC,TUSC2,PNRC1,RAP1A,MIR920,SERPINB1,TRIM54,NPTN,TMEM127,HTRA2,BEND6,MRLN,IL20RB,SOCS5,HSPA5,LDLRAD4,ARPP19,TULP3,MIR149,CD46,IGFBP3,SSH3,MAVS,ZBTB17,MIR760,FURIN,EEF1E1,MIR876,MIR661,TYROBP,KCNAB1,CLIC2,CDKN2AIP,MAD2L1BP,SCG2,CNTFR,LILRB1,ID1,YWHAH,FRZB,CCL3,ATP5F1A,SRSF12,IL6ST,BTN2A2,ETFBKMT,CSF2,BARX2,GBE1,IL2RB,MOSPD1,MIR605,MIR200A,EPHA4,MIR7-2,MIR942,ADD2,PPIA,CDC42,FTH1,IFT172,FERMT2,CSNK1E,TIMP3,MAGEH1,IGF1R,SFRP1,RTRAF,MIR429,CCR5,STAT2,ANKRD6,IL1R2,EXOSC4,MIR551B,RGN,SUB1,IKZF5,DNAJB9,BANF1,MIR215,CHST11,DLG1,IGBP1,CNOT6,ZCCHC7,BECN1,CBLN1,FIS1,DICER1,OS9,SKAP2,KDM1A,TSN,MIR29C,MIR488,BTG3,IGFBP4,MIR936,TOB2,PRMT2,HGS,MAP2K1,MIR511,HDAC5,DHX9,SPP1,MIR25,SPINT2,MIR517B,MIR30D,COL3A1,BHLHE40,MIR1226,CXCL1,RNF167,HCFC2,ZNF345,ISG15,THAP7,RLIM,MIR370,MIR597,MIR346,MIR449B,TLE1,RAB29,MAPRE1,PPP2R1A,TNFAIP8L2,SUV39H1,SUFU,PI16,KLHL22,NQO1,HELLS,IMPACT,APOBEC3H,SGTA,EPCAM,FCMR,MIR212,MIR503,RBCK1,APOC2,RNF139,C1QTNF1,MIR638,ZNF668,LHX2,RPS26,B2M,IFRD2,BRINP2,RAP2C,CNOT8,MIR99B,ARHGAP1,GABBR1,ITGAV,SAP18,RAD1,MIR26B,MGMT,TMEM38B,PCGF2,ARF4,SEC14L1,APLNR,TLR4,ZBED3,TMEM14A,KLF4,TGIF2LX,STK4,MAEL,ST6GAL1,ACTL6B,BRINP1,SDC4,MIR671,LEPR,SOD2,ZC3H7A,OAZ1,PCGF6,TNFAIP6,SYNJ2BP,SOST,MAP3K3,MIR764,PAIP2B,GJA1,MIR17,MIEN1,FOXC2,SLC25A27,AIF1,RBM5,NDN,TMSB4X,TMEM39A,CDK9,SDR16C5,RIOX2,TBC1D10C,TYMS,GREM2,SLC25A5,CITED1,IK,RB1,MIR338,PHF12,NAB1,HFE,CTDSPL2,PFDN5,BCL6,NSFL1C,TOPBP1,ORMDL3,HMG20A,DDAH1,PLG,EMILIN1,TBC1D24,ARHGAP12,FBP1,MIR1296,ITGB8,HINFP,OAZ2,BRMS1L,CAPZA1,RBPJ,XCL1,NAB2,HMGA1,ACTB,TWSG1,MIR9-2,TNF,SHMT1,LRRTM2,PDE12,SLC25A4,SEC13,CDK8,MIR191,ATP1A1,E2F6,PPP2R5A,SMG8,MCL1,MIR580,RPL10,ORMDL1,KCNIP3,TNFRSF1B,LEPROTL1,PLCB1,TLR9,MIRLET7D,MIR196B,CDC73,DNAJB2,LPCAT3,IFNA2,DNAJC3,PPP1R10,FABP4,CDKN3,MIR204,MIR423,ZBTB33,FOXS1,NMI,DSTYK,MAD2L2,VPS18,UCN,ANXA4,CD80,FAM89B,HMX1,ERRFI1,AKT2,PLXNC1,COPS2,TMBIM1,SLX1A,GPR137,MIR607,DAPK3,PRNP,MIR130B,OXSR1,MIR589,ELF1,ERLIN2,RAB23,MIR223,ACVR1C,GPM6B,NKX3-2,GNAQ,LSM5,MMP9,CD86,PYDC2,ACAA2,SOX21,BAX,MIR379,GP9,TOM1L1,IL6,FAS,MTRNR2L3,ANP32B,KIT,DLK2,MIR1251,MET,MIR631,MIR320A,UBE2D1,KLRD1,PHF1,PSMG2,NR1H2,PLA2G5,E4F1,TSG101,MIR448,SYVN1,CDK5RAP3,TMEM88,MIR569,AKT1,IL1B,MIR182,CLP1,HERC4,PPP3CA,FAM107A,SLC6A1,MIR595,MIR211,RADX,TLR6,EXOSC8,MIR675,SKIC8,MIR639,CALR,PTRH2,IGF1,MIR604,UCP2,UBE2W,ENY2,CNOT2,INPP5E,NPVF,MT3,MXI1,CCND3,TNFAIP3,RBBP4,GSTP1,MAX,TXN,MIR922,FOXP2,MAGED4B,MIR30E,NR2E1,PIK3R1,RAN,MIR24-2,NR0B1,CUL3,CRYM,OSGIN2,MIR493,OPRK1,ELK4,MIR218-1,H2AJ,NIBAN2,MIR194-2,MIR455,MIR298,FABP5,MIR532,HIGD2A,ABHD2,HSPB6,MIR769,MIR137,CEP85,NF2,RNF115,CAPZA2,PRRT1,MIR874,CCAR1,MIR652,RGS6,ELK3,TRIM35,MIR891B,GTF2H2,MIR572,IL18,PBLD,PIK3CG,HNRNPA2B1,PMP22,FASLG,INSIG2,EID1,BMERB1,FIG4,CBX7,IFT52,PAFAH1B1,NLE1,MAGOHB,ETV6,MIR143,TES,MIR139,PDCD4,STAU1,SESTD1,NEO1,TLR2,RPS13,MIR183,CYP1B1,FKBP4,MRPL13,CTNND1,DUSP9,CLEC12B,PPIF,PTHLH,CSNK1A1L,PICK1,RNF10,NUP62,MAPKAPK5,HPGDS,NHERF1,IL2RA,MRTO4,H2AC25,MIR7-1,OPRL1,DCUN1D3,PIH1D1,DRD1,CACNB4,MIR16-1,DERL2,ACVR1B,SAV1,ARFGEF1,TMBIM6,CH25H,BFAR,NR1I3,ALKBH4,CREB3,STK11,CCAR2,MIR592,NME2,RGL2,POLDIP2,MAGEB1,MIR616,SGF29,HDAC6,MIR208B,KCTD10,ATRAID,SCYL2,WEE2,SPTBN1,NIF3L1,ASB1,EGFL7,PTCRA,LACRT,DUSP1,BIRC2,TNRC6C,ASIC1,PDCD1 |
| 2.892e-31 | -70.32 | MYCN (MYCN proto-oncogene, bHLH transcription factor) | protein interactions | 4613 | 1363 | 575 | 19454 | 5460 |
PRPF19,PSMD3,PRDX1,CRIP1,MRPS35,DPY30,TRA2A,DDX23,LYZ,RPL23,THOC2,MYEF2,GATD3,RPLP1,HP1BP3,RBIS,NOP58,ODC1,BUD31,CCAR2,RPL7,CGGBP1,ZNF593,CACYBP,MAK16,SAP30,EZH2,KBTBD3,SF3B5,PLD3,GTPBP1,PPAN,ARGLU1,RPS24,G3BP1,SRSF4,MRPS17,NOP16,CUL3,ZNF668,RBM15B,MCM3,MCM8,NOA1,LMNB1,SP1,PFDN6,FAU,ZNF22,CPSF1,RAN,RPL37A,RPL7L1,RPL35,DYNLL1,SNRPB2,GNB1,RPL19,H1-5,PRDX3,ATP5PO,APOBEC3C,ADNP,NDUFA5,THOC3,UPF3B,CCDC86,NUP50,HAND2,PSMC1,COIL,SKP1,G3BP2,MPHOSPH10,PSMD7,SRP14,RCHY1,SEC23A,POLR2I,PRNP,TOP1,ATP5PD,MRPL11,LBR,DDX39A,EEF1A1,RPL15,ILF2,MRPL51,MRPL49,SLC25A10,ZNF787,ZC3H11A,RING1,HINT1,LSM4,PAK1IP1,THRAP3,HSPE1,RPS13,MRPL22,SNRPG,PRDX4,NDUFB10,SEC13,ATP5F1A,NONO,TUFM,ZNHIT3,TADA3,HOXC4,CASC3,EIF4A3,RTRAF,PRKRA,RPS20,TXN,YES1,SLC25A4,RPL13A,TECR,RPL22,RBFOX2,SAP30BP,RPS14,CPSF4,CNP,RBMS2,MRPS34,CDK1,P3H1,JUP,LMNA,HSP90B1,RPLP0,NOL7,MACROH2A2,CSTB,MTDH,DGCR8,EIF5B,GTF2I,SMC4,HMGB1,RPL4,NHP2,SS18,AATF,MRPL9,PPIB,CASP12,YWHAB,HSPB1,SRSF1,POLR2L,EED,CORO1C,FAM98A,MEAF6,PAIP1,LYAR,TCP1,TRIR,UQCRH,HMG20A,UBL5,MAX,TOP3B,PRSS35,CBLN4,SMNDC1,SLC1A2,ZRANB2,RPL18,PABPC1,RBM3,SREK1IP1,RTCB,ZNF609,H1-6,NUP42,RPL28,POLDIP3,HNRNPDL,RPL39,CHTOP,H1-10,FTSJ3,ELAVL4,PRSS1,NSA2,THOC6,MCAT,GTPBP2,LORICRIN,SF3B4,SNRNP40,RPL27A,NUP62,ZNF362,MRPS18A,MXD1,SNRPA,PYM1,XRCC5,HDAC5,MRPL34,HSPA8,EP300,YAF2,HNRNPA0,GON7,STAU1,SAP18,MRPS7,CMSS1,RBM17,CSNK2A1,TMA16,SNRNP70,RPS2,CDK12,RPL10A,SYNCRIP,SDHB,SFRP1,DELE1,RPS16,NKAP,RBM42,TMPO,DKC1,CDC5L,SURF6,SRFBP1,MRPL47,TNRC6C,WBP11,RPAP2,ZMYM3,MRPL36,CHAMP1,RBM34,IK,NOSIP,SNIP1,SLC25A11,MRPS18B,SLC16A1,RPL3,KPNA2,SRSF12,CAPZA1,RPF2,CEP85,SUB1,TIA1,RPS17,EIF3G,DNAJC10,LSM6,ELAVL2,CALU,RRP7A,RPS3,CREB1,LIG3,PSMC5,EIF2S2,MRPS28,MRPS21,MKKS,SRPK2,NMI,GTF3C4,NDUFAB1,SNRNP27,MRPL10,NTPCR,ZNF326,IDH2,BANF1,CWF19L1,HNRNPH2,PRDX6,KDM1A,MRPL40,RBM22,MRPL41,TOMM20,HSPA5,MARS1,HMGA1,HNRNPA1,BCL7C,ZNF207,ZCCHC9,SKIC8,MRPL18,MRPS26,HNRNPD,MPHOSPH6,RPL9,RPL8,ZNF664,MRTO4,RPLP2,ATP6V1A,BRD9,INA,AGK,PPIA,SRSF10,DHX15,CSNK1E,NEU1,RPL29,RPN1,NDUFS6,NME1,RPS11,POLR2D,SNRPE,SART3,SLC25A5,HSPD1,HNRNPA2B1,PCNA,MRPS11,SRSF7,BAG2,RPS27A,GTF3C3,SSRP1,SMARCE1,MRPL16,RPS29,FYTTD1,YWHAZ,ZCRB1,BRCA1,RPS5,PFDN2,HSP90AA1,LSM14B,GNG12,RSRC1,SNRPD1,SNRPD2,ZMAT2,RPS9,POLR2F,MRPL23,PRDX2,ACTB,BMP1,TUBB,NDUFAF4,ERH,PRRC2A,USP5,ACTL6A,CDKN1A,USP39,FKBP10,MFAP1,SLC25A3,NKAPD1,FAM168B,CYFIP2,SRI,YTHDF1,NOP53,MRPL57,GRSF1,MOV10,SPATS2L,FAM133B,NME2,WDCP,RPL12,KRR1,PRR3,RB1,RPL35A,MRPL50,THOC1,NCBP2,MRPS23,MRPL24,CWC15,NDUFA2,AURKAIP1,FCF1,LLPH,PQBP1,NKRF,TCOF1,CPNE2,RPL23A,HUWE1,CDK2AP2,MRPS18C,RPL26,DNAJC8,SDF2L1,PAIP2,PPIG,DNAJC19,MRPL53,CINP,TUBA1B,EIF2AK2,ENO1,RPS12,ALB,ZBTB17,TMOD3,RPP25L,DEK,GNAI2,JUNB,VIRMA,SF3A1,UBA52,ZCCHC17,RPL26L1,HNRNPH3,WTAP,HMCES,PPIH,MRPL17,FBXW7,BRIX1,MRPL20,LSM8,UTP23,DDX50,BAZ1B,RAB5C,RPL6,YWHAG,DNTTIP1,XPO1,NGDN,DDX1,MAGOH,RPRD1A,FUBP3,RPS10,HNRNPL,NOB1,ISG20L2,SNRPD3,SNRPA1,HSP90AB1,MIEF1,TUBA1A,RPS7,EEF2,TUBB4B,SMARCB1,TAF10,RPS23,RPL31,BCL7B,ABCF1,LSM14A,EWSR1,MYO1B,FAM168A,HNRNPF,DCTPP1,RPS4X,CBLL1,TFG,PRPS1,MYC,COX6B1,HNRNPC,HNRNPAB,BTF3,CPSF2,SNRPB,CIRBP,MRPS25,H2AZ2,RPS26,VDAC2,MIDEAS,SMU1,MRPL13,MATR3,MANSC1,CBX5,POLR2B,RPL10,ZC3H14,MRPL12,NUFIP2,CSNK1A1,NGRN,DDX39B,SMARCD3,TIMP3,RPS28,SF3B1,DDX5,RAMAC,FXR2,TRA2B,SRSF2,EEF1G,ENY2,COX5A,TPM3,GAPDH,RPL24,SMCHD1,NOL12,AKAP8L,SSBP1,MRPS9,ALYREF,RPL32,DSTN,XXYLT1,PLG,RPS27L,MIF,MALSU1,MXI1,STRBP,ESS2,CBX3,RP9,MRPL33,MAP1B,MRPL52,DHX9,MRPS33,HNRNPK,MEPCE,RPL17,SUGP1,SMARCA5,TRIM32,RPL7A,CFL1,MRPS16,MECP2,IGF2BP1,RBM7,CDKN2AIP,UQCRC2,SF3B6,RBMX2,PHAX,MACROH2A1,RPP25,RSL24D1,POLR1D,AGO1,DDX4,TFIP11,CSNK1G3,MAIP1,RPL27,LIN7C,DDX46,DLAT,RPS15,WDR3,GRPEL1,CLU |
| 3.053e-31 | -70.26 | env (Envelope surface glycoprotein gp160, precursor) | protein interactions | 155971 | 1501 | 622 | 19454 | 5460 |
CAV1,POLR2I,KCNMB2,CD151,ARF6,AIFM1,HACD3,TOPBP1,FGR,CD9,PSMD7,P2RY1,APOBEC3F,CXCL13,HDAC6,NFKB1,BMPR1B,CALR,CD36,PRDX4,EIF3E,IL6,ARF4,VWF,RNF20,FCN2,CCL2,CNR1,CD80,TSPAN7,NTRK2,SLC6A3,TMX3,HINT1,KLF10,DLG1,GLUL,B3GALT2,SRP72,GPR34,ILF2,HSPA13,EEF1A1,SOCS3,MAP1LC3B,FOLR2,IFNA10,F11R,LDHA,MGAT1,TXN,RAB14,UBE2I,PTEN,GANAB,TNFRSF1B,EIF4A3,GABRA2,CASC3,TUFM,NONO,ATP5F1A,IL2RB,SEC13,NDUFB10,CREB3,CTSD,CSK,RPL4,TPST1,MTDH,EGFL7,SQSTM1,ARPC2,VIP,DPEP3,VIPR1,MGAT4B,MME,RPLP0,TM9SF1,PDIA2,B3GALT1,HSP90B1,TMX4,CDK1,CCL3,FUT8,CSF2,OS9,RPL7,SPTAN1,G0S2,TRIM35,THY1,IL10,PHB1,THOC2,DNM2,NQO1,BCL2L1,CD58,PPP3CA,LYZ,CDKN1B,DDX23,IDO1,TRA2A,EIF3D,FGF1,ADCY2,STOML2,CMKLR2,PRDX1,AP1M1,SRSF4,G3BP1,ERP29,JAK1,APLN,CHST10,AKT2,PLSCR1,RNASE6,PLD3,RNF126,AP2S1,STIM1,TXNRD1,RPL19,AP2M1,CLDN3,PIGK,CYB5R3,RAN,CPSF1,CD79B,APOBEC3G,TNFAIP8,NTRK3,LMNB1,SLPI,FAS,GLT8D2,TOMM40,G3BP2,TNFSF10,IL1A,IL1B,CLDN1,OPRK1,UPF3B,MCRIP2,CXCR4,EPO,CCL21,VAV2,PPARG,ABCB1,ATP5PO,RAB6A,PPP1CB,TIMM13,PRDX3,IL2RG,TLR6,CDC5L,CD28,SST,CD4,RGS1,MCL1,COX4I1,SFRP1,CD274,SYNCRIP,GLT8D1,ITK,IFNA2,CD247,RPS2,CYP2D6,BECN1,CAMP,CCL4L1,TUBG1,CCL5,IL12B,IL12A,CHST2,TOLLIP,SRPRB,MAN1A2,RPL3,SOD3,ERO1A,SLC25A11,RUSF1,PSMC3,TAB2,NHERF1,NFE2L2,ACVR1,BMPR2,CD209,TFRC,PPP3R2,IL1R2,CD38,CCL20,SRC,ROCK1,PRKCE,CCR2,GPX1,PLCB2,IL2RA,PSMC5,CREB1,RPS3,CALU,ATP1A1,KCNMA1,DNAJC10,PTPN11,AKT3,CCL8,HSPA5,TOMM20,EIF4E,RNASE1,CLCA1,LCP1,ACP5,PRDX6,HNRNPH2,TLR2,MRC1,ANGPTL2,CHRNB2,PRKCA,CXCR6,BTG2,SDCBP,XBP1,CAPN1,RETN,TCP1,GANC,SDC4,SRSF1,POLR2L,IL3,SERPINC1,YWHAB,DRG1,SFTPD,IKBKB,CCL11,PPIB,CST3,MAPK4,TNFAIP6,SIVA1,PAEP,IL13,IFNG,IGF1,VDAC1,KRAS,PDIA6,ICAM3,RUVBL2,CD83,PABPC1,CCT8,ADCY3,NCR3,RPL18,SLC1A2,SERPINA3,FASLG,MAX,APLNR,GPNMB,GTF2F1,GTF2F2,BST2,SF3B4,NFKBIA,NFKBIB,PRSS1,ICAM1,SPCS3,CXCL1,TMEM38B,RER1,STAU1,EMC1,HNRNPA0,RNF5,EP300,TRIM22,DDIT3,HSPA8,P4HA2,FOS,IL4,GPR15,SDC2,PAK2,LILRB1,CD59,SLC16A10,CLDN4,B4GALT6,RB1,CHID1,LDLR,NLRP1,SCG5,ACTA2,KRR1,TIMM8B,TREML1,HRAS,OSBPL8,POR,LAMP3,HM13,CCR6,FAM133B,MOV10,TUSC3,SGMS2,ERLEC1,IL23A,PTGES,IGF1R,IFNA13,NKRF,SFXN1,RAB1A,LTA,TLR4,HHIP,ADORA3,SERPINA1,SOD2,AP1S2,POLR2G,C1QC,ALPL,CAMK1,GPX7,CTLA4,TIMM8A,TM4SF1,TOR3A,GNAI2,UBB,B3GALNT1,CPT2,NDP,ALB,PTCRA,MSN,EIF2AK2,CTNNA1,ENO1,TLR8,TUBA1B,GXYLT1,CCL1,IL2,SMAD2,AP2A1,SDF2L1,SMPD2,MGAT5B,HMOX2,IFNAR1,SFTPA1,HSPA14,CCR4,CCR3,PIK3R2,PDHB,SPCS2,PRKCB,IDH3A,SOD1,HNRNPH3,FTH1,SEC22B,PIP5K1A,XCL1,DHX15,PPIA,SRSF10,PRKCQ,INA,CX3CL1,MAP1LC3A,RPL8,RPL9,ST3GAL4,HNRNPD,PDCD1,CISH,HNRNPA1,VPS26A,PIK3R1,PDIA3,FLOT1,TAPBPL,TNF,PLCB1,SELENOP,SRSF7,TLR7,HNRNPA2B1,HSPD1,MAP3K11,SLC25A5,POLR2C,ITGB5,POLR2D,IL7,CTNNA2,RPN1,JUN,RPL29,MAPK10,ACTN4,NEU1,RAF1,VDR,B3GALT4,CPT1B,SELL,B4GALT4,TUBB,CD40LG,ACTB,B4GALT3,THBD,AP1G2,POLR2F,RPS9,PI3,CD86,BAD,NLRP3,BAX,F2,RAB11A,OPRM1,CCR7,TERT,RABAC1,BIRC2,CD1D,DNAJC3,FKBP1A,ERAS,CDKN1A,PGRMC1,CA12,TOR1AIP2,ASRGL1,RRAGA,CD2,TLR1,LMAN1,LCP2,CXCL9,DSTN,ALYREF,IER3,TNFRSF14,RPL24,GAPDH,FCGR2B,FCGR2A,CD81,CXCL12,COX5A,DPP4,TSPO,RPL17,CTSC,HNRNPK,H3C1,DHX9,CCR5,FURIN,GNAI3,CAPN2,PIK3CA,SURF4,PLA2G12A,FGL2,TP53,PLA2G5,CXCR3,TAC1,IFI6,CTSB,STAT5A,B4GALT1,SEC61A1,CDIPT,AP3S2,KCNB1,IGF2BP1,OAT,TLR9,ENDOD1,IL15,CFL2,PRKACB,CFL1,CCNB1,RPL7A,AKT1,BCL6,BCL2A1,LSM12,PGK1,IRF3,NBN,PML,ITM2B,SLC7A4,FCAR,CHPF2,CX3CR1,DYRK2,MGAT4A,CXCL8,CDC42,CHST7,GLRX,C1QTNF1,RAB1B,ACHE,CD63,ANXA4,FCGR1A,DDX1,IFNB1,QPCTL,CTNNB1,DKK1,RPL6,RAB5C,PTDSS1,CXCL10,RPS4X,MX2,RUVBL1,ROCK2,HNRNPF,PSMA1,MMP9,OAS1,PIK3CG,GNA11,CCR1,PLS3,TUBB4B,TUBA1A,ETFB,RPL10,ESR2,NCKAP1,PSMB6,POLR2B,MBL2,MATR3,TAGLN2,STAT2,STAT1,CD3G,TNFRSF9,DLG4,VDAC2,VEGFA,SERPINH1,KCNA3,FIS1,CCT2,PSMD1,HNRNPAB,PRMT6,HNRNPC,LDHB,CHST9,ST3GAL1,MYC,ST3GAL2,COX6B1,ITGAV,CHRNA7,EEF1G,PHB2,TRA2B,THBS3,DDX5,SF3B1,TAPBP,CD40,CXCL3,DDX39B,BMPR1A,MMP14,MAP2K1,IL15RA,EDEM3,CHST1,SEC62 |
| 3.347e-31 | -70.17 | EFTUD2 (elongation factor Tu GTP binding domain containing 2) | protein interactions | 9343 | 1425 | 596 | 19454 | 5460 |
CDK1,MRPS34,LMNA,HSP90B1,LSM2,RPLP0,WDR83,RPS14,PSMC4,EEF1E1,SPR,SNRPN,EDF1,EIF3J,ELP3,CNP,GTF2I,EIF5B,HMGB1,RPL4,USP8,SMC4,NHP2,MBD3,POLDIP2,LRRC8D,NCDN,PRPF4,CSTB,PNO1,MTDH,PIP4K2C,ATP5F1A,TUFM,USP14,PPP1CC,GMPS,NONO,KPNA6,AR,ZNF622,LDHA,MAGOHB,TXN,RPL13A,SLC25A4,RPL22,PELP1,EIF4A3,RTRAF,RPS20,TRIM24,ILF2,MRPL49,SRP72,CCDC47,MRPL11,EEF1A1,RPL15,GGCT,CTNNBL1,LSM4,THRAP3,OLA1,CTNND1,MRPL22,RNF20,RPS13,MDC1,PRDX4,SNRPG,EIF3E,MSH6,SLC25A10,EMC2,HSD17B10,PC,EXOC2,FGR,EMC4,HDAC6,GTF2E1,ZMYND11,LRRC40,TOP1,ATP5PD,G6PD,ZBTB2,AIFM1,HACD3,SRP14,SRPRA,RCHY1,SEC23A,PPARG,ATP5PO,NDUFA5,RTF2,MYL6,H1-5,PPP1CB,PRDX3,ETF1,MCMBP,PSMC1,UNC45A,G3BP2,SKP1,UPF3B,CRY1,HADHA,CCDC86,TTC1,RIT1,CUL3,NOP16,RIOK2,RFC5,RNF40,MCM4,MCM3,RBBP4,DYNLL1,RPL35,TSN,RPL19,SNRPB2,FAU,PELO,EIF3K,RAN,AP2M1,STIM1,EZH2,SF3B5,EIF1AX,GNB1L,FEN1,TXNRD1,GFPT1,GTF2E2,SAP30,RBBP7,LASP1,G3BP1,GNL1,AP1M1,MCM6,MRPS17,RFC3,ANP32B,RFC2,NDUFA4,RPS24,DDX23,AHSA1,RPL23,PRDX1,PSMD3,CLPX,PRPF19,DPY30,MRPS35,ATG7,EIF3D,NOP58,CCAR2,SNX1,RPL7,SPTAN1,BUD31,NDUFS8,ZNF593,CACYBP,PHB1,XPO5,HP1BP3,RPLP1,SDCBP,RPA2,HEXIM1,UBE2M,ACACA,HECTD1,SPTBN1,NTPCR,KDM1A,MRPL41,RBM22,EIF4E,ZC3H15,MARS1,HSPA5,EXOSC4,HNRNPH2,PRDX6,EIF3G,DNAJC10,TRIM23,SERPINB1,ATP1A1,MAT2A,MORF4L1,GSTK1,PTPN11,SUB1,RPS17,BUB3,MRPS21,GMDS,SRPK2,RPS3,MRPS28,EIF2S2,GPD2,CHAMP1,IK,ARPC3,DNAJC2,SELENOF,TBC1D4,PSMC3,RRM1,MRPL47,WBP11,CDC40,KPNA2,SRPRB,PDRG1,CAPZA1,NOSIP,SNIP1,MRPS18B,RPL3,TUBG1,LANCL2,SNRNP70,RPS2,RPL10A,KARS1,CMSS1,CSNK2A1,COPS5,RPS16,DKC1,IAH1,TMPO,RBM42,CDC5L,EEF1B2,GTF2B,SYNCRIP,TRAPPC3,PIH1D1,RPL27A,EMC1,HNRNPA0,STAU1,SAP18,MRPS7,PYM1,RFC4,SNRPA,FLYWCH2,XRCC5,HSPA8,HDAC5,FTSJ3,H1-10,THOC6,ATP5F1B,FBXO22,SNRNP40,EFHD2,SF3B4,GTF2F1,GTF2F2,ZRANB2,MTA2,CRKL,RPL18,SUPT5H,ISG15,KIF2A,KRAS,RPL28,HNRNPDL,RBM3,PABPC1,TOP2B,CCT8,RUVBL2,DNAJB4,RPAP3,PDIA6,RTCB,AGR2,HSPB1,DRG1,YWHAB,GSTM3,PPIB,PPFIBP1,NT5C2,EIF2S1,FAM98A,TCP1,TRIR,LYAR,DYNC1I2,LANCL1,SRSF1,EED,CHMP1A,RARS1,SH3GLB2,SF3A1,TXNL4A,IRF7,LSM8,BRIX1,RPA3,PRIM2,PPM1G,HELLS,GID8,KIN,PPIH,SDF2L1,AP2A1,CDC73,DNAJC19,RALB,HSPA14,RPL26,COPE,UBE2L3,VIRMA,DEK,CCNF,CTNNA1,ENO1,EIF2AK2,TUBA1B,METAP2,CMBL,MSN,RPS12,NDUFS3,HINFP,CCT5,CD2BP2,TSSC4,HUWE1,DNAAF10,FARSA,FN3KRP,PTGES3,TCOF1,PQBP1,RPL23A,ECD,GRSF1,H2AC14,RPL35A,MDM2,CDK9,MRPS23,HDHD3,RPL12,EIF4E2,KRR1,USP39,ISOC1,SLC25A3,ARCN1,CDKN1A,TXNL1,PSMA3,EMG1,BRCA1,YWHAZ,HSP90AA1,PFDN2,RPS5,ILK,PYCR1,SMARCE1,PRPF31,PRDX2,STARD7,MRPL23,TUBB,ACTB,MAT2B,PRRC2A,USP5,FAM91A1,SNRPD2,SNRPD1,RPS9,RPN1,CHMP4C,EXOSC3,NME1,PRKAG1,POLR2C,RPS11,SART3,SNRPE,ANP32A,NAA15,HSDL2,OTUD6B,PPP2R1A,S100A10,RPS27A,SSRP1,RAD21,HSPD1,NEK9,SLC25A5,HNRNPA2B1,PRPSAP1,BAG2,SRSF7,SKIC8,HNRNPD,MRPS26,VCPIP1,PDAP1,HMGA1,PDIA3,MAP1S,HNRNPA1,HYPK,AGK,PPIA,DHX15,RPL8,RPL9,MRTO4,PSMB5,KRT8,RPLP2,SSR1,TFIP11,CYC1,LUC7L3,RPS15,RPL27,BAP1,DLAT,GLOD4,MRPS16,IGF2BP1,PDCD4,UBE2H,CARS1,SLC25A1,PSMB2,SMARCA5,RPL7A,CFL1,TXNDC12,SF3B6,PSPC1,CSNK2B,PTPMT1,CBX3,CAPZA2,CAPN2,NUPR1,ATP5PB,TP53,RPSA,KIF1C,ESS2,PSMA5,MRPS33,CSE1L,HNRNPK,MEPCE,RPL17,PSME1,DHX9,SMCHD1,SHC1,RPL24,KPNA1,TSNAX,MAP4,TPM3,GAPDH,ELOC,CAND1,FZR1,MIF,MYL12A,SSBP1,MRPS9,RPL32,UBE2N,ALYREF,DSTN,EIF4B,CSNK1A1,TRMT112,MTF1,MRPL12,UFL1,NDUFS2,FXR2,SRSF2,EEF1G,PHB2,SERPINB6,PACSIN3,DDX39B,RPS28,SF3B1,DDX5,CCT2,CIRBP,H2AZ2,MRPS25,RPS26,SERPINH1,MDH1,MYC,HNRNPAB,LDHB,HNRNPC,BTF3,PSMD1,UFD1,BAG3,CPSF2,SLC1A3,SNRPB,TAGLN2,MATR3,RPL10,APEX1,NCKAP1,VDAC2,PAPSS2,PRMT5,SMU1,TUBB4B,PLS3,PTRH2,SMARCB1,RPS23,TRMT1L,DHX38,TUBA1A,EEF2,RPS7,HNRNPF,PSMA1,RUVBL1,ROCK2,RPS4X,DCTPP1,TFG,PRPS1,RAB18,RPL31,FBXO3,ABCF1,EWSR1,AK2,DDX1,MAGOH,IFI16,ASB1,RPL6,WWP2,RAB5C,PTDSS1,YWHAH,YWHAG,CTNNB1,BTF3L4,DDRGK1,NOB1,RPS10,SUMO2,SNRPD3,SNRPA1,HSP90AB1,CCT7,SIN3A,PSME2,HDHD5 |
| 4.022e-31 | -69.99 | negative regulation of biological process | biological process | GO:0048519 | 5737 | 2024 | 18204 | 5365 |
TLR6,EXOSC8,RADX,MIR211,MIR595,FAM107A,HERC4,PPP3CA,CLP1,SLC6A1,MIR182,ELAVL4,TAPBPL,IL1B,MIR569,AKT1,MAX,GSTP1,TXN,RBBP4,TNFAIP3,RETN,CCND3,NPVF,INPP5E,MXI1,MT3,UCP2,CNOT2,UBE2W,ENY2,PTRH2,DKC1,MIR604,IGF1,MIR639,SKIC8,CALR,MIR675,MSH6,PHF1,PSMG2,HNRNPAB,UBE2D1,KLRD1,MET,MIR1251,DLK2,MIR631,MIR320A,ANP32B,MTRNR2L3,KIT,FAS,TMEM88,SYVN1,CDK5RAP3,MIR448,TSG101,E4F1,PLA2G5,NR1H2,MIR589,MIR130B,PRNP,OXSR1,DAPK3,MIR607,TMBIM1,SLX1A,GPR137,PLXNC1,COPS2,AKT2,HS3ST5,ERRFI1,FAM89B,HMX1,TOM1L1,IL6,MIR379,TRAF3IP2,BAX,USP38,GP9,SOX21,PAIP1,LSM5,GNAQ,CD86,ACAA2,PYDC2,MMP9,ACVR1C,MIR223,NKX3-2,GPM6B,RAB23,ERLIN2,ELF1,CDKN3,PPP1R10,DNAJC3,FABP4,CDC73,IFNA2,DNAJB2,LPCAT3,MIR196B,MIRLET7D,LEPROTL1,TNFRSF1B,ORMDL1,KCNIP3,PLCB1,TLR9,MIR580,RPL10,MCL1,PPP2R5A,E2F6,SMG8,CD80,ANXA4,UCN,VPS18,MAD2L2,FOXS1,NMI,DSTYK,MIR423,MIR204,ZBTB33,HDAC6,SGF29,MIR208B,RGL2,NME2,MIR616,MAGEB1,POLDIP2,CCAR2,MIR592,ALKBH4,STK11,CREB3,BFAR,NR1I3,CH25H,ARFGEF1,TMBIM6,ACVR1B,DERL2,SAV1,ASIC1,PDCD1,TNRC6C,LACRT,BIRC2,DUSP1,YES1,EGFL7,ASB1,PTCRA,SPTBN1,NIF3L1,SCYL2,ATRAID,WEE2,KCTD10,CSNK1A1L,RNF10,PICK1,HCAR1,PTHLH,PPIF,VIP,RNF26,CLEC12B,DUSP9,CTNND1,MRPL13,FKBP4,CYP1B1,GCHFR,MIR183,RPS13,TLR2,DRD1,PIH1D1,MIR16-1,CACNB4,DCUN1D3,OPRL1,MIR7-1,H2AC25,MRTO4,IL2RA,NHERF1,MAP2K6,HPGDS,NUP62,MAPKAPK5,EID1,FASLG,PMP22,INSIG2,PIK3CG,HNRNPA2B1,PBLD,IL18,GTF2H2,MIR572,MIR891B,TRIM35,ELK3,STAU1,SESTD1,NEO1,SERPINB11,TES,PDCD4,MIR139,MAGOHB,MIR143,ETV6,SPOPL,NLE1,IFT52,PAFAH1B1,FIG4,CBX7,BMERB1,NIBAN2,ELK4,OPRK1,H2AJ,MIR218-1,MIR493,CRYM,OSGIN2,CUL3,NR0B1,MIR24-2,RAN,PIK3R1,TRIM10,NR2E1,MAGED4B,FOXP2,MIR30E,MIR922,MIR652,RGS6,PRRT1,CCAR1,MIR874,NF2,CEP85,CAPZA2,RNF115,IL15,MIR769,MIR137,HIGD2A,HSPB6,ABHD2,MIR532,FABP5,MIR194-2,MIR298,MIR455,THAP7,ISG15,ZNF345,HCFC2,BHLHE40,CXCL1,RNF167,MIR1226,COL3A1,MIR30D,SPINT2,MIR517B,MIR25,SPP1,DHX9,RAB29,TRIM8,TLE1,MIR346,MIR449B,MIR597,RLIM,MIR370,CBLN1,FIS1,DICER1,ZCCHC7,BECN1,DLG1,CHST11,MIR215,CNOT6,IGBP1,IKZF5,BANF1,DNAJB9,EXOSC4,MIR551B,SUB1,RGN,IL1R2,STAT2,ANKRD6,CCR5,MIR429,HGS,PRMT2,HDAC5,MAP2K1,MIR511,TOB2,MIR936,BTG3,IGFBP4,MIR488,TSN,MIR29C,SKAP2,OS9,KDM1A,BARX2,IL6ST,ETFBKMT,CSF2,BTN2A2,SRSF12,CCL3,ATP5F1A,YWHAH,ID1,FRZB,CNTFR,LILRB1,SCG2,SFRP1,MAGEH1,IGF1R,RTRAF,CSNK1E,IFT172,FERMT2,TIMP3,FTH1,CDC42,PPIA,ADD2,EFNA3,MIR7-2,MIR942,MOSPD1,IL2RB,GBE1,MIR200A,EPHA4,MIR605,IGFBP3,MIR149,CD46,TULP3,ARPP19,HSPA5,IL20RB,SOCS5,LDLRAD4,OPHN1,HTRA2,TMEM127,MRLN,BEND6,SERPINB10,NPTN,TRIM54,MYD88,H1-10,MAD2L1BP,CDKN2AIP,MIR661,CLIC2,TYROBP,KCNAB1,EEF1E1,MIR876,FURIN,MAVS,SSH3,MIR760,ZBTB17,FBP1,MIR1296,OAZ2,HINFP,ITGB8,ABHD5,TBC1D24,EMILIN1,ARHGAP12,PLG,HMG20A,DDAH1,ORMDL3,BCKDK,TOPBP1,NSFL1C,PFDN5,CTDSPL2,HFE,BCL6,MIR191,ATP1A1,SLC25A4,CDK8,SEC13,LRRTM2,PDE12,MIR9-2,SHMT1,TNF,ACTB,HMGA1,TWSG1,FGF3,RBPJ,NAB2,XCL1,CAPZA1,BRMS1L,FOXC2,AIF1,SLC25A27,MIEN1,MIR17,GJA1,MIR764,PAIP2B,NAB1,PHF12,MIR338,SLC25A5,GREM2,RB1,CITED1,IK,TBC1D10C,TYMS,RIOX2,SDR16C5,NDN,RBM5,CDK9,TMSB4X,TMEM39A,IP6K1,TGIF2LX,TMEM14A,ZBED3,KLF4,APLNR,TLR4,SEC14L1,ARF4,MIR26B,SAP18,RAD1,PCGF2,TMEM38B,UGT1A1,MGMT,ARHGAP1,MIR99B,CNOT8,GABBR1,ITGAV,RAP2C,BRINP2,MAP3K3,SYNJ2BP,SOST,TNFAIP6,ZC3H7A,OAZ1,PCGF6,SOD2,LEPR,SDC4,MIR671,ACTL6B,BRINP1,MAEL,ST6GAL1,STK4,MIR212,MIR503,FCMR,EPCAM,APOBEC3H,SGTA,IMPACT,KLHL22,NQO1,HELLS,SUFU,PI16,PPP2R1A,TNFAIP8L2,MAPRE1,SUV39H1,B2M,IFRD2,RPS26,GTF2I,LHX2,C1QTNF1,ZNF668,MIR638,RNF139,TRIM44,APOC2,RBCK1,RNF128,LSM4,SMAD4,MIR578,UBE2G2,MIR1271,EID2B,NDNF,MIR938,NOP53,SERPIND1,ASZ1,HYAL2,SHLD1,MIR1227,SLC1A1,SP2,CTNNB1,TSNAX,H2AC7,MAGOH,PDCD10,DR1,MIR384,SNX5,CD164,PACSIN3,NAA16,STK26,ATP5IF1,MIR221,MIR155,SS18,NUP153,NCOA5,RRN3,MIR497,UBE2N,SLC8A1,CARTPT,LMO4,GRIA1,MIR377,CREBZF,IL22,GNAI2,EIF2AK2,CRY1,TMEM215,ABCE1,SMCHD1,CD34,DEFB114,JAK2,PTEN,MCPH1,MIR500A,MED31,LRP6,STAT1,USP3,ADRB1,ZNF263,NEUROD2,MIR10A,PAK5,MAP4,VEGFC,IFNGR1,PPARA,PELI1,PRL,MIR186,DMAP1,LDLR,AURKAIP1,ENO1,MIR633,RFX5,CSK,ABHD6,STAMBP,ERP29,CRMP1,BTG1,YWHAG,THRAP3,FGR,LDB2,RNASEL,BRAP,ANAPC2,WDR82,CPNE1,MIR21,FGFBP1,GNAZ,SMURF1,MIR330,DNM2,PROS1,HACD3,UBE2B,PEBP1,GPRASP3,SYNCRIP,NGDN,ELAPOR2,MAEA,CD36,TPT1,MIR129-1,BAP1,TCF21,DXO,NDUFS3,IREB2,LDOC1,FOXD3,HYPK,SRSF10,LIG3,IFI27,PC,SERPINB9,RPS7,NFKBIL1,NKX3-1,ADIPOR1,STK38,PSMA1,TMIGD1,CLU,RINT1,MIR23B,MINAR1,CCL23,OTULIN,CISH,MACROH2A2,RAP1A,MIR920,PNRC1,SERPINB1,TUSC2,DDIT4L,TFRC,ELOC,SARM1,MAGEB10,LMBR1L,NR2F6,NT5C2,STC1,H2AZ2,SFTPD,GRM2,CTLA4,PLN,GSKIP,CD38,CD2AP,NEK2,ZBTB25,FKTN,GADD45A,CAMK2N2,CRADD,MIR491,SNAI3,TERT,MIR141,EIF2S1,IL15RA,SRI,FGF13,UBXN2B,PABPC1,HCLS1,BMPR1B,PML,FGL2,ZNF175,PHB2,CBLL1,MIR148B,LEP,SQSTM1,POLR2G,WIF1,CD200,EPS8,KRIT1,MIR601,NME1,SST,MMP28,KCNJ11,MGARP,MIR765,SERPINH1,PIWIL3,SMARCA5,SH3BP4,DAG1,HOXB8,TRIM45,DYNLL1,MIR873,MIR34B,GNB1L,PLCL1,MIR7-3,CCDC3,MIR618,MIR563,TLR8,CIPC,MYT1L,MIR296,NTRK3,EIF4EBP3,MIR153-1,MIR100,GTF2IRD1,MIR625,GSTO1,BRMS1,TRIM3,TFE3,EI24,MIR549A,DRAP1,SRSF4,LPXN,UBASH3B,NFE2L2,DNAJB4,SOX3,FBXO7,PRMT6,MT1A,SMARCB1,IVNS1ABP,BMPR1A,MIR152,DDIT4,KLK3,ZNF177,ZBTB18,MIR147B,TNFSF18,CREBBP,PROX1,WASL,CEACAM5,TM4SF20,GCLC,DYRK1A,FABP7,GSTM2,SPC24,FGF10,NCK1,IRF6,ADAMTS1,PAK1IP1,KRAS,IL1A,CSTA,ADAMTS20,SLC35F6,PICALM,LITAF,ATP1A2,PYM1,ARHGAP25,TRIM22,MIR656,CTNNA2,OGN,FAM3A,LTA,TWIST2,CRHR1,OAS1,HNRNPC,RNF126,SUMO1,COPS5,NLRP6,H2BC11,IRF7,SMAD1,MIR425,MIR200C,CAV2,XPO5,ZBTB26,ACTN4,MIR1260B,NFIL3,BTF3,EED,MIR557,CTDSP2,GDI2,APOBEC3D,CYP26A1,PDCD5,MIR105-2,RPS6KA4,MIR194-1,OSR2,CDK1,SNIP1,DDT,MIR553,MIR126,MIR184,MYC,MIR142,MIR490,HSPB1,CDC20,DAPK1,SLC43A2,ITM2A,MIR106B,CASK,LRRC14,HCRT,DLX1,GLRA1,MIR324,SNRNP70,ZHX1,UBE2I,APOBEC3F,PSEN1,TNKS2,MTM1,PTN,RNF113A,CYP2D6,MIR31,SERPINB6,BRCA1,MIR342,SMAD2,AGAP2,CDKN2D,PIM2,ST3GAL1,IFNB1,CAV1,SOCS3,RBBP8,PRDX4,MCOLN1,MEPCE,TNKS,RBFOX2,GABPA,TRIM46,MIR875,HRAS,PYCARD,MBL2,ABHD17A,DFFA,FEM1A,HMGB1,BCL7B,RGS2,LBX1,MPIG6B,VPS28,CX3CR1,MIR145,MSX1,CDKN2C,NKX6-2,TAGLN3,PPP1R1B,RBBP7,NAA15,MIR505,CRLF3,DDRGK1,MIR636,PTGFR,STN1,MIR640,FERD3L,IL10,MIR611,RAF1,SLC39A10,SRSF2,CCR2,F2,PIP4K2C,CDH11,BCL7C,PLSCR1,RNF144B,LMAN1,NEFL,PRKCA,ACVR1,EIF4E2,H1-6,AZIN2,ZBTB45,ASIC2,STRADB,CTTN,ADNP,DAP,CGAS,INPPL1,APOBEC3B,HSP90B1,HAPSTR1,CCL8,MIR590,TOMM70,SMG9,DDIT3,EYA3,MIR586,POLE3,DNAJC2,PRDX2,NKAP,P2RY1,MIR340,ADORA3,ADORA1,SIX5,NKIRAS1,AZI2,GPR173,MIR770,ITGA6,CYGB,UBE2D3,ATG101,UBP1,RGS1,RRAGA,LPAR1,CXCL8,MIR133B,CTSC,FKBP8,ARF1,CLIC4,SVBP,LCMT1,PPARG,MIR30A,PAQR3,CCDC22,FATE1,F11R,MIR193A,UFD1,GABARAPL2,PGR,MIR106A,SESN2,PRKCQ,SLA2,MIRLET7G,LEMD3,YTHDF2,UPF3B,EZH2,MIR554,ADCK1,CHRNA7,FSTL1,EPO,PTGDS,MNAT1,SERPINA3,MIR28,AP1AR,NR4A2,MKKS,IKBKB,MIR422A,EGR1,DUSP26,SERTAD2,GPC1,SLC25A31,RPL26,WNT7A,MIR374A,SIAH2,TGFB3,VDR,TCAF2,MAP1B,BAK1,RGS5,MIR877,MIR345,KICS2,SPRED1,PPP1R11,BRD9,NFKBIA,SAP30,SIRT7,PIP4P2,TAX1BP3,TCF23,MIR331,MIRLET7B,IL2,MIR130A,TRIM63,PAK2,PAIP2,HIRA,CCND1,TSC22D3,CAAP1,MIR492,CNR1,AR,SOD1,PFDN4,TERC,BUB3,CD59,XBP1,RPL13A,PID1,GLCE,MIR450B,PRKCE,PARL,MIR10B,RGMA,PHC1,TCEAL1,PPP3R2,CCL28,RPGRIP1L,MIR187,PCSK9,NRP1,ACP5,MIR125A,B4GALT1,LMNB1,CLIP3,SNTA1,SPRY1,HAX1,KLHL25,TENT4A,SMARCE1,ACTL6A,PPP2CB,MIR1224,CD274,FOXP3,AKT3,MX1,ID4,EIF4E,ZBTB2,TP53INP1,GNAO1,PADI2,CHMP1A,ASPM,BAHD1,LRRTM1,MAGEC2,GNRH1,MACIR,MOSMO,MMP14,SFN,DNAJB6,SYT4,AQP11,NACC2,MIR648,MIR96,HDAC3,IFNK,SH2D1A,MIR383,ZBTB16,ZNF24,MIR148A,BABAM1,HP,OPTN,HHIP,MIR454,TP53INP2,MIR887,SLC35C1,PAX6,TXNIP,WNT10B,MIR577,SAR1B,NOG,TESC,PRR5L,EAF2,FBXW7,MIR129-2,TRIM5,MALSU1,APOBEC3C,SYK,BOLL,HNRNPL,NUF2,TXNDC12,TMOD3,MAGEA4,GPAM,TRIM32,RASD1,CNOT6L,RAB33B,GPR171,KBTBD6,LAMP3,VSIR,MIR363,NAIF1,CERS2,MIR101-1,VPS54,PIAS1,VAMP3,DPP4,MIR632,MIR32,FEZ1,ZBTB39,ACOT13,XRCC5,TBK1,CYRIB,APOBEC3A,C1D,SLC12A2,MIR373,MYLIP,H2AC1,G6PD,SERTAD3,CCL2,PHF23,SEMG2,PSMC5,DUSP6,IGF2BP1,NPSR1,NPPC,CIART,PDE2A,POU1F1,DNAJC1,RBM42,BACE1,TNFAIP8L1,CD40LG,RNF41,THY1,MIR939,PDE4B,MIR140,CCDC85B,KLF3,RB1CC1,SERPINI1,H1-3,TMEM176B,SUPT4H1,ROCK1,PHAX,MIR15A,CDSN,PIK3CA,CD47,IL17F,NTF4,NLGN1,RGS7BP,TCIM,APEX1,ICAM1,SPTAN1,FZD4,AREL1,NDUFAF4,STMN2,SOX14,RXFP2,BEX3,TNFRSF9,PIK3R2,MIR944,YWHAZ,OSM,PRKACB,BSCL2,MIR301B,VEGFA,CTSA,IL23A,MTA2,SATB1,TIMP1,SAMHD1,NSMCE3,CARD19,PPM1B,FGF23,VSTM2L,EIF3E,PRELID1,NUDT16,CCR7,STAT6,RNF8,SPINK13,SEMA5A,DDX4,ADRB2,SRSF7,C9orf72,MBD3,HAND2,GAS8,MIR367,TMEM182,RFLNA,SPOCK1,MIR600,DKK1,VAMP8,TRAFD1,RERE,ADD1,SESN3,LSM2,MIR9-1,JAGN1,OTUD7B,SHISA2,ALB,DPEP1,MIR192,LRP3,KLHL15,DUSP3,MAP2K3,SNAI2,MIR489,DLG3,DCAF5,BRINP3,IFRD1,HNRNPA0,CPEB1,CSNK2A1,GHRL,AZIN1,DHRS7B,PAEP,NDFIP1,CBL,SOX9,RHEB,ERO1A,BAG3,IRF8,CCR1,SAP30L,MIR558,TMEM176A,EIF4EBP2,FKBP1A,CTTNBP2NL,CD200R1,PELO,ING5,PRPF19,TRIM29,NR1I2,MIR339,CDC5L,MAP3K12,HEY2,IRF3,KLF12,MIR1225,CFL1,PARD6A,STK3,OPRM1,RNF34,HNF1B,MIF,IL12A,BCL10,MIR132,MIR302B,FLCN,ARFIP1,MIR484,MIR761,DUSP19,SOCS2,CRYAB,AGO1,NUPR1,FZR1,KCNB1,RGS19,CCL5,SPEF1,CST3,RORB,UBAC2,MIR3173,DYRK2,TLR3,RPS14,FXN,NKRF,DGCR8,MIR146A,SCML1,MDC1,THAP1,MIR662,IL4,MIR504,SWAP70,MIR452,RUVBL2,USP5,DKK3,ING2,EFNA5,AP2M1,MIR150,LANCL2,GPR35,CPTP,CHID1,MIR101-2,HECW1,MIR649,RNF5,MIR98,KDM2A,CHRDL1,DUSP10,MIR628,PKIA,STUB1,DNAJC10,CDK5,HEXIM2,MIR615,PLAC8,CXCL12,MIR624,ING1,ERLEC1,PHB1,RPA2,MID1IP1,CAMK2N1,NDUFAF2,PPT1,MUL1,CX3CL1,MIR1298,IRF4,H1-5,ARF6,CLDN3,CASC3,MIR552,CSNK2B,PDCD1LG2,H2AB1,MIR214,YWHAB,MIR502,PPM1D,ZHX3,CASTOR2,CCL25,NLRP3,ZNF655,ILK,RNF152,EID2,NPY5R,NLRP2,WDR44,MIR301A,TNFAIP1,GGT7,ZNF365,LSM14A,TENT5C,SUPT5H,MIR16-2,MDFI,CDKN1A,MIR105-1,PAX9,MIR147A,CRBN,CER1,DLG4,IFI6,JADE1,TIMP4,ACKR3,HSPA8,BAG2,PTPN1,MIR1-1,DDX5,NCBP2,MIR188,MDM2,HENMT1,API5,SDCBP,MIR583,TP53,CDK2AP2,RETREG1,CHMP4C,SCFD1,UFL1,RBM15B,CXCL13,TP53TG5,CDKN1B,HOMER3,MIR218-2,NAA35,MIR193B,PIWIL1,MIR195,MIR1249,DROSHA,MIR198,WDR6,MIR335,ZNF692,LGALS3,TRIM15,ZBTB14,CYP27B1,H2AC6,MIR92B,MIR99A,PRMT5,CEND1,SELENOS,TANK,GRB10,ISG20,LZTFL1,SDHAF2,MIR9-3,DRD3,MT1E,GMNN,DPH3,ZMYND11,LMNA,MIR136,STARD13,MIOS,TBC1D4,CTSK,BACH1,NPR2,CRTAP,GPX1,ANXA7,VDAC2,EP300,BOK,OVOL1,WDR77,PIK3R3,PLAA,ARRDC3,CDK12,PHF21A,CTDSP1,CRKL,TRIM24,HTRA1,SNX12,ADRB3,AATF,H2AC4,MIR643,MIR206,PPP1R8,GSK3A,AKR1A1,B4GALT7,DEDD,MAF1,LIMS2,STXBP1,BCL2L1,TSPAN15,TIRAP,PKIB,MIR573,BST2,MIR449A,MT1X,TMEM196,MTA3,GPR37L1,SERPINA5,MORC2,JUN,OVGP1,MIR885,CBX3,VDAC1,HSPD1,SERPINA1,RSAD2,MIR1-2,USP2,CAMLG,MIR107,BGLAP,PCDH17,PEA15,MIR190A,FOXP1,UBE3A,IL12B,PCBP4,MIR185,MSX2,LILRA2,MIR375,HADH,MIR519D,INHA,MIR30B,CD9,MIR548C,RTN4,RGS10,ABCC2,FMC1,MIR651,TIA1,RGCC,LST1,MIR593,SNAPIN,MIR210,POU5F1,MIR197,ZNF592,RMI2,MIR33B,RERG,SIN3A,LYAR,CHMP2A,RRAGB,BCL2A1,FCGR2B,ATF3,AKR1B1,STAP1,MIR653,SETD5,MIR205,PCGF3,KLF10,MIR924,MIR599,EIF4A3,TEX19,CRHBP,TAF9,RHBDD3,CCN3,HNRNPD,TMIGD3,IRF2BP1,TRIM62,SLC7A11,SCML2,DUSP22,SMAD3,ISCU,MIR24-1,CCL19,MT2A,TMEM59,PLAGL1,MIR378A,TRIB1,MIR802,THBD,MIR1180,NUDT12,MIR181D,NAE1,MIR222,TRAF6,POU3F4,CCNF,LRIF1,NFKB1,ARG2,TESK1,MT1M,P3H1,MIR937,PSPC1,IRF2BPL,HINT2,SOSTDC1,HEXIM1,TFPI,PLCB2,HNRNPK,ATF4,NOVA1,TRIM21,MTMR2,NRDE2,SRGN,FAIM,XPNPEP1,PSMB4,ANGPT1,PPID,ADRA1A,SRC,MIR34C,CDK20,MEF2A,PRKRA,OAZ3,LGR4,USP30,MIR135B,DTL,ZBTB5,BIRC5,CAMSAP2,TENT2,IFNG,TAB2,LMO3,DDAH2,MIR551A,NTRK2,TFIP11,IFI16,PGK1,TLCD3B,METTL14,NBN,TCEAL7,CGRRF1,BPIFB1,SHOC2,CTNNBIP1,RGP1,INSM2,ITM2B,IRF1,DNAJC5,ADGRG1,BMPR2,MIR542,LYPLA1,EXOSC3,BNIP3L,MIR29A,EDC3,MECP2,NDC80,MIRLET7I,MIR181C,PIWIL2,CDH13,TPPP,SNX33,VPS4B,GREM1,MIR940,TOM1L2,ADTRP,MTDH,SOX2,PTPN22,TMEM115,RAP2B,IRF2,TRIM37,C1QC,HSBP1,FMO1,RING1,PCNA,SEC22B,ATP5F1B,MIR612,MXD1,SPRED2,ZBTB38,SLC6A3,DBNDD1,SVIP,SRPK2,NOTCH2,MIR144,CRYBA1,CHP1,TGFB2,CSTB,IFI35,MAFG,CIRBP,TADA3,MIR20A,CCL21,GPX4,BAZ1B,TNR,CTNNA1,FZD3,CHGA,SHC1,PRKCB,CTBP1,ZNF174,RAP1B,MAD2L1,USP14,NABP1,ATP2B4,PFDN2,MIR708,TMEM170B,TMOD2,RIT2,MACROH2A1,TGIF2,USP15,SMAD5,SOCS4,MAGED2,DAD1,H2AC13,CDK5R1,MIR190B,CD83,PSRC1,KLF9,PELI3,MOV10,APLN,INPP5K,HTR2A,CREB1,FRMD8,IER3,TMSB10,SNCB,ZFAND6,APOBEC3G,PRDX3,PTGES,TDRD7,GPR17,MIR556,HSPB2,ZNF207,PEG10,G3BP1,SPON1,FMO2,MIR216B,HNRNPA1,WWP2,GLO1,THOC2,S100A11,ZGLP1,ARB2A,RPS27L,LILRB4,ARL6IP5,ZBTB42,TRIM26,AP2A1,HBEGF,GFI1,ZMPSTE24,SLPI,CNKSR3,RUNX1,ZMYM2,PKIG,IFIH1,MIR208A,IFT57,WWP1,SNX3,TCTA,PTPRZ1,TAX1BP1,CD28,CBFB,HSP90AB1,ERLIN1,FKBP1B,VGLL4,MSTN,CAV3,ZCCHC17,TNFAIP8,LYPLAL1,MEF2C,BEND5,PFDN6,TRIM11,ACHE,RC3H2,USP8,SMG5,CAB39,RHOB,MIR23A,ZNF304,MIR361,AGER,STXBP6,CXXC5,CORO1C,MIR495,EPHA2,TRAF2,FBXO31,CBX5,NMBR,TRIM6,RPS3,H1-1,FOXP4,ETF1,LBH,ADIPOQ,ROCK2,H2AZ1,MIR567,YAF2,MIRLET7C,CGGBP1,MIR1277,ACOT8,MIR581,RHOH,UFM1,MIR657,DDR1,TFDP2,DIS3L,LDB1,STK38L,AIPL1,XAF1,RAG1,FBXW11,SPINDOC,H2AX,NKIRAS2,OGG1,MIR424,CFDP1,ATAD1,CXCL10,TNFRSF14,PSMD10,ATG3,SPHK2,PTPN11,HUWE1,CCL11,CEP97,MICB,ENC1,TRIM27,DHRS3,AZGP1,GHITM,NONO,CDK6,PTPRQ,HELT,VASH1,FGFR1,ATXN1L,SCAMP5,MIR155HG,PIWIL4,MIR216A,VPS72,MITF,ZNF451,MIR609,IL13,MIR34A,FHIT,VPS4A,DIPK2A,TAF7,PFDN1,TENT5D,IDO1,MIDEAS,CYP7A1,RPL23,SFRP4,MIR626,PTGER4,CSNK1A1,STK24,DCP2,PDE9A,ZBTB6,TSPO,BTG2,TMOD1,RAP2A,RNF20,MIR711,JUP,GPNMB,CAPG,PYCR1,ESR2,TPRA1,FZD6,CHRNB2,OSBPL8,MTRNR2L7,EZH1,IL7,MIR1262,TPBG,SLC6A4,LSM6,RAD21,CLN8,CNOT7,TGFB1I1,MIR934,GAPDH |
| 1.998e-30 | -68.39 | tat (Tat) | protein interactions | 155871 | 1718 | 692 | 19454 | 5460 |
ADCY3,SLC1A2,RAB4A,ISG15,SUPT5H,FASLG,IL13,IFNG,SATB1,IGF1,KRAS,DNAJB4,FBXO11,CD83,TOP2B,TGFB2,CASP12,UTP6,MDFI,TNFAIP6,SDC4,SRSF1,IL4,SDC2,APOBEC3A,NEK7,PAFAH1B1,GH1,CLDN4,SAP18,MT2A,EP300,DDIT3,COX6A2,FOS,SNRPA,ICAM1,GABRG2,RORB,ATP5F1B,GTF2F1,BST2,NFKBIB,TFRC,EGR2,SP4,RRM1,H2BC14,IL12A,TCEA2,RPS2,CD247,LY96,SMAD4,CCL5,RBM17,TMPO,CD4,RGS1,CD274,GTF2B,MRC1,ACACA,STAT6,HEXIM1,H2BC11,XBP1,CAPN1,PPP1R8,AIF1,TLR2,SLC6A4,AKT3,SRC,PRKCE,GABPA,CCR2,GTF2H2,PSMC5,LIG3,MOXD1,GTF2E2,NUP153,E2F4,TXNRD1,RFC2,MCM6,RBBP7,SRSF8,PLSCR1,AKT2,PPP3CA,MT1X,CDKN1B,UBE2D1,MAP3K14,IDO1,ADCY2,TAF7,CSF2,CACYBP,IFI27,POLR3F,SLC19A3,IL10,GJA1,MYEF2,PPP2CB,SP2,PPARG,PPP1CB,H1-5,PRKAB1,IL1B,CLDN1,PMAIP1,OPRK1,SAT1,CXCR4,SP1,FHIT,CTSK,LMNB1,FAS,NTF4,PDE4B,GNB1,SNRPB2,DYNLL1,CLDN3,RAN,SMAD1,SOCS3,LBR,EEF1A1,MTA3,VWF,PDE2A,CNR1,TF,CAMK2G,SLC6A3,LTBR,PSMD7,MED21,GTF2E1,BAK1,ORC5,PRNP,SRP14,MACROH2A2,LMNA,CNP,MX1,CCND1,PSMC4,FABP4,MBD3,SMC4,GTF2I,NPM3,H2BC12,VIPR1,DCAF16,PPP1CC,CREB3,SMAD5,YES1,LDHA,PTEN,GUCY1B1,OPTN,ISG20,SMARCB1,CLDN12,H2BC1,H1-3,CXCL10,COX7B,RUVBL1,PSMA2,OAS1,CDK5,CYP1B1,DDX1,H2BC17,IFNB1,CTNNB1,GPR85,YWHAG,IFI16,HSP90AB1,SNRPD3,SNRPA1,WDR82,CD63,PSME2,SIN3A,MED31,MAP2K1,ITGAV,PHB2,GPX5,SRSF2,FXR2,TRA2B,DR1,DDX5,CD40,CD34,BMPR1A,H1-1,SNRPB,PSMA4,CREBBP,COX6B1,PSMB6,MATR3,STAT1,TNFRSF9,DLG4,FGF7,VEGFA,CAPN2,AGER,PIK3CA,CBX3,RPL17,MEPCE,MLC1,PSME1,CCR5,MED27,MIF,CDK6,HSD11B1,PDE1B,COX7B2,GTF2H4,RGS2,PGK1,IRF3,PML,RPL27,KCNB1,TLR9,CISD1,CFL1,ATF4,CCNB1,TRIM32,CDC20,POLR2D,ITGB5,IL7,PPP2R1A,RAF1,FOXP4,FLOT1,GTF3C3,KIT,TNF,PCNA,HNRNPA2B1,HSPD1,DICER1,ZNF175,MED4,PPP2R5A,DHX15,PRKCQ,SRSF10,CD1A,CX3CL1,PSMB5,COX7A1,IFIT2,CRYAB,PSMB7,SUPT4H1,CDKN1A,CA12,ACTL6A,PPP2R3A,PSMA3,WNT2,SETD7,HSP90AA1,BAX,IRF1,OPRM1,BMP1,MED17,ACTB,CD40LG,POLR2F,SNRPD2,CD86,GRIA1,GPX7,UBE2V1,DRD1,H2AJ,EGR1,MT1E,LTA,TLR4,PPP1R12A,UPK1A,PDE1A,GTF2A2,LAMP3,ERCC3,H2AC14,THOC1,SCG2,AK5,RPL35A,RB1,ACTA2,SMAD3,HRAS,HNRNPH3,CDK7,CCNA2,MED30,CCR4,BRIX1,PIK3R2,TCEA1,COL1A2,SMAD2,ZNF687,JUNB,UBB,ALB,HEXIM2,GTF2A1,TUBA1B,MTA2,KIF2A,HILPDA,SERPINA3,CDCA7L,GALC,RUVBL2,PABPC1,SMAD9,FKBP4,IKBKB,TRIM34,SHC3,EIF2S1,LTB,MEAF6,FAM98A,POLR2L,IL3,SIGMAR1,SSR3,TRIM22,HSPA8,XRCC5,RFC4,CXCL1,TIMP1,PAPOLA,GPNMB,PSMD6,PSMD4,GTF2F2,NFKBIA,TAF2,PSMC3,TAB2,BMPR2,NFE2L2,PPP3R2,DUSP1,H2AX,CD38,CCL20,CDK4,MNAT1,IL12B,KPNA2,SOD3,RPL3,BACE1,IFNA2,IGFBP4,TUBG1,POLB,RBFOX3,KLF9,CDC5L,CD28,GRM1,CEBPG,COX4I1,SDHB,UTP15,PRKCA,ZNF326,CCNH,GTF3C4,SPTBN1,CCL8,HSPA5,FMO3,H2AC13,KDM1A,H2BC9,PTGER2,TIA1,SUB1,PTPN11,TNFAIP3,NMI,ROCK1,PPP1R10,GPX1,PLCB2,IL2RA,CH25H,EIF2S2,PSMA6,CREB1,AP2S1,CDK5R1,PGGT1B,STIM1,EZH2,RFC3,G3BP1,LAMB2,COX8A,JAK1,MT3,ATF3,NQO1,BCL2L1,LYZ,PSMD10,FGF1,ATG7,HEBP2,PSMD3,NOP58,HP1BP3,PHB1,MYL6,ABCB1,TAAR1,FOXP2,TNFSF10,PSMC1,IL1A,PFDN6,MCM3,RFC5,MAD2L1,RBBP4,AP2M1,FOXP3,ILF2,DMAP1,PSMB9,MAP1LC3B,IL6,EIF3E,SOCS2,CCL2,HSPE1,ADIPOQ,CD80,HSD17B10,HINT1,KLF10,H2AC25,HDAC6,NFKB1,BMPR1B,G6PD,CAV1,POLR2I,MAP2K6,UBP1,H2AZ1,SSU72,CCL19,H2AC7,CDK1,CCL3,EDF1,MYL12B,AATF,GABARAP,CRYZ,NUCKS1,B2M,MTDH,GPX4,SQSTM1,MME,IRAK1BP1,TUFM,RUNX1,ATP5F1A,IL2RB,CTSD,CSK,IFNA10,MAGOHB,TRIM24,PRKRA,TNFRSF1B,TAF10,CCR1,FGF10,TUBB4B,TUBA1A,MX2,HNRNPF,PSMA1,MMP9,PIK3CG,FBXO3,XPO1,LAMP2,BAZ1B,PAPOLB,SUMO3,MT1M,TRMT112,GPC4,IL6ST,TIRAP,PSMB3,SF3B1,KCNA3,H2AZ2,ATG3,CCT2,BAG3,PSMD1,PRMT6,LDHB,MYC,ESR2,POLR2B,CBX5,CD3G,ADH1B,DLST,GPX6,FURIN,CDK8,NDST1,FGL2,TP53,CTSC,PSMB10,CSE1L,H3C1,PSMA5,DHX9,GPX2,GLCE,TAF9,H2AC4,SHC1,GAPDH,CXCL12,COX5A,DPP4,MYL12A,SNAP25,CXCL9,CAND1,RAC2,SLC39A10,SSBP1,GPX3,CX3CR1,LUC7L3,CXCL8,BCL6,DDX46,ABCG2,IL15,OGG1,CFL2,PRKACB,PSMB2,IFI35,AKT1,RGL2,SMARCA5,CXCR3,MACROH2A1,PPP2R5E,FGFBP1,SART3,POLR2C,BZW2,PRKAG1,RPN1,JUN,SSRP1,MT1A,AHCYL1,PSMD12,SRSF7,PLCB1,SLC17A5,HNRNPD,CISH,HMGA1,PIK3R1,VEGFC,NDNF,TSPAN18,MAP1LC3A,PSMB4,H2AC1,ERAS,STXBP1,NOTCH2,CCND3,MED11,PPP2R2C,TERT,TRIM5,PRKD3,SLC7A11,BRCA1,YWHAZ,CAPG,PDE7A,TAF11,JAK2,SELL,TUBB,LGALS3,POLR3B,SNRPD1,BAD,ADORA3,SOD2,POLR2G,CAMK1,PPARA,MAP2K3,SMN1,H2AC6,IFNA13,RAB3A,BRD3,ID1,NME2,TRPC1,SUV39H1,PMM2,MDM2,CDK9,IL18,PSMB1,CXCL14,COX6C,XCL1,PDE8A,CXXC1,CCR3,MEF2A,COL3A1,IRF7,TTR,PRKCB,PPM1G,SOD1,IL2,PPIG,AP2A1,PIM2,SYP,TAF5L,POLR3H,SLC11A2,EIF2AK2,ENO1,CCL1 |
| 2.451e-30 | -68.18 | VCP (valosin containing protein) | protein interactions | 7415 | 1381 | 578 | 19454 | 5460 |
PTDSS1,RPL6,RAB5C,CNOT2,LAMP2,F7,CTNNB1,YWHAG,YWHAH,NDUFV2,GSTO1,MGMT,STX5,SH2D1A,WDR82,COMMD6,SUMO2,RPS10,CCT7,HSP90AB1,SPC24,RPS7,TUBB4B,PLS3,GNA11,TRIM21,EWSR1,RUVBL1,PSMA1,SYN3,PSMA2,COX7B,RPS4X,PSMA4,HNRNPC,LDHB,SFN,MYC,UFD1,PSMD1,BTF3,FBXW11,PSMD14,H2AZ2,CCT2,MDH1,SERPINH1,CRMP1,LMBR1L,VDAC2,ADH1B,PRMT5,TAX1BP1,STAT1,TAGLN2,MATR3,ESR2,RPL10,POLR2B,PSMB6,PSMB3,MAP2K1,PPT1,CNDP2,PACRG,CAV2,EIF4B,NUDT2,DDX5,ADRB2,PHB2,EEF1G,GAPDH,RPL24,NT5DC1,RAC2,MTAP,ADD1,DSTN,RPS27L,VCPKMT,LMAN1,INSIG2,TP53,KBTBD4,ESS2,RP9,NUPR1,SLC25A24,HNRNPK,TGFBR2,NUP107,PSMA5,CTSC,RPL17,MEPCE,CCNB1,SMARCA5,AKT1,PSMB2,RAB2A,ST13,CFL1,ALKBH5,CDKN2AIP,UBE2H,SORD,ABCG2,PDCD4,UQCRC2,PSPC1,CSNK2B,IRF2BP1,PAAF1,CDC42,FBXL19,PTPN22,CYC1,PML,NBN,BAP1,RBM23,DERL1,PGK1,UGP2,PDIA3,ATG9A,HNRNPA1,PPM1B,DICER1,RB1CC1,VCPIP1,DCAF11,HAX1,HNRNPD,PSMB5,PSMB4,RPL9,RPL8,RPLP2,KRT8,ATP6V1A,MAP1LC3A,DNAJB9,STK3,CEP19,DHX15,HSBP1,EGLN3,PPIA,DIRAS3,BUD23,RAF1,PPP2R1A,ACTN4,RPL29,GABARAPL1,FAF2,PRKAG1,CHMP4C,BZW2,NME1,RPN1,RPS11,BCKDK,HNRNPA2B1,SLC25A5,HSPD1,BAG2,PCNA,SAR1B,FLOT1,RPS27A,GTF3C3,TMED7,PSMD12,RAB11A,PIK3R3,NIBAN2,ACO2,CAPG,PRPF31,YWHAZ,RHOB,BRCA1,HTRA2,CNIH4,BAX,SCFD1,HSP90AA1,BAD,RPS9,SNRPD1,ACTB,TUBB,EIF4A2,PRDX2,IP6K1,CLIC4,FCHSD2,JAK2,PGRMC1,CDKN1A,DET1,ARMCX3,VPS18,VAPB,PSMB7,ANXA7,SLC25A3,DUSP9,PSMA3,CYFIP2,CMAS,RNF11,PXMP2,PYGB,SLC25A46,ERCC3,GOLPH3L,HM13,UBXN10,POR,MUL1,NME2,SMDT1,RPL12,PSMB1,TES,DERL2,MRPS23,MDM2,CCT5,SELENOK,GBE1,H2AJ,UBE2V1,NDUFS3,ACTR2,SERPINA1,PPP1R12A,FAF1,MRFAP1,TTC4,HUWE1,RNF115,PTGES3,CIAO1,HMOX2,SDF2L1,COL1A2,CDC73,TUBA1B,CTNNA1,ENO1,CCNF,PTCRA,ALB,COPE,MGST3,PNP,DEK,VIRMA,FERMT2,UBB,SEC22B,DDAH1,UBA52,UQCRC1,RNF103,METTL14,SHOC2,HNRNPH3,RARS1,HELLS,RPA3,SOD1,RTN4,PIK3R2,FBXW7,PDHB,TTR,CDC42EP4,BRIX1,TMUB1,PPFIBP1,CNOT8,PPIB,AGR2,FKBP4,YWHAB,PPP1R11,HSPB1,CORO1C,LYAR,RHOH,DYNC1I2,TCP1,EIF2S1,UQCRH,RANBP1,MSX2,TNPO2,ISG15,CCDC134,CAAP1,RPL18,RHOBTB1,FAM136A,MTA2,CCT8,PABPC1,CYP2C9,RUVBL2,KRAS,COPS7A,H1-10,ELAVL4,OSGEP,EFHD2,NFKBIA,SNRNP40,PSMD6,VCF1,PSMD4,ATP5F1B,DES,TOM1L1,RPL27A,NUP62,UBAC2,ADSS2,PLAA,PIH1D1,XRCC5,EP300,HDAC5,COX17,HSPA8,EYA3,EMC1,SAP18,FAM20C,XAF1,EDEM1,SELENOS,KARS1,ZFAND2B,COPS5,SNRNP70,USP15,COMT,COX4I1,EEF1B2,SYNCRIP,AIP,COQ8A,AKR1B1,CD4,SVIP,TMPO,CDK4,UBL4A,H2AX,UBXN2B,HADH,ACTR1A,ACADSB,SFTPC,TFCP2,TFRC,SESN2,PSMC3,RNF8,ZBTB25,IDH1,ABCE1,RPL3,MRPS18B,TMEM33,PTPN11,MORF4L1,MAT2A,DNAJC10,CALU,GZMK,ATP1A1,SERPINB1,PSMA6,RPS3,PSMC5,ADRM1,TRIM54,KCTD9,BCCIP,SMURF1,SUCLG2,SUMO1,SPTBN1,CFTR,NEK2,GABRA1,MRPL10,ZNF326,IDH2,RPA2,VPS4B,ACACA,HECTD1,UBE2M,HEXIM1,UGDH,HNRNPH2,HSPA5,MARCHF5,PRPF19,PSMD3,PRDX1,UBXN6,PSMD10,TRAF6,UBE2D1,PPP3CA,NQO1,RPL23,PDCD10,CDKN1B,PPP2CB,PHB1,DNM2,TSG101,ATXN10,RPL7,SPTAN1,OS9,RAB11B,ERLIN1,NDUFS8,TXNRD1,FEN1,MARCKSL1,STIM1,EZH2,VAMP2,RNF126,OTULIN,CYB5B,PLD3,COX8A,ERP29,ETFA,G3BP1,EMC8,LASP1,ANP32B,RFC3,CUL2,CUL3,KDSR,USP13,MCM3,GGH,RFC5,SAMHD1,MYO6,WDR20,FAS,RIT1,UBE2S,RAN,EIF3K,DIO2,AP2M1,RPL35,RPL7L1,RBBP4,MTM1,AKR1C2,TNPO3,RPL19,H1-5,WDR77,PRDX3,RND2,RNF7,ADNP,PPARG,RHBDL3,WBP2,HADHA,COMMD2,NSFL1C,MCMBP,SKP1,DNAJC22,G3BP2,PSMC1,FBXL4,COIL,ISYNA1,CALR,NFKB1,HDAC6,PSMD7,CRBN,TOP1,POLR2I,PRNP,ARF6,PPP1R18,CD151,CAV1,G6PD,AKR1C1,BCS1L,MAP1LC3B,EEF1A1,RAD23B,GLUL,EMC2,HINT1,SEPTIN7,THRAP3,TOM1,HSPE1,SEM1,CTNNBL1,PRDX4,RPS13,OLA1,CTNND1,ARF4,SEC13,PYCR2,CSK,CTSD,NONO,AR,PPP1CC,USP14,TUFM,NTAQ1,ATP5F1A,TDP1,NAPA,CYRIB,STUB1,OPTN,ACAT1,CAB39,GSK3A,SNX3,RPL13A,RAB14,LDHA,RPL22,PSMC4,ATG16L1,RBFOX2,EIF3J,LSM2,GRM2,HSP90B1,PTP4A2,JUP,LMNA,CDK1,TIMM23,RPLP0,EPHX1,PNO1,SIRT7,PRPF4,NCDN,ARPC2,SQSTM1,SYVN1,HMGB1 |
| 5.608e-30 | -67.35 | cytoplasm | cellular component | GO:0005737 | 12081 | 3851 | 19108 | 5553 |
MSX2,QRSL1,CLBA1,ID4,UGCG,SYT2,HSP90AA1,CTNNBL1,MYO6,PGM1,PLA2G12A,EYA3,RHCG,TEDC2,HSPA14,YTHDF2,ANKRD50,GFM2,PSENEN,AP3S2,CTTNBP2,MXD1,G6PC3,ZDHHC8,NELL2,VAC14,MBL2,CYP4F8,RAB1A,SIAH2,RUVBL2,MREG,EIF5A2,CCR2,KGD4,SYVN1,PROX1,VSTM2L,CST11,NEU1,PLCL1,ATP5PF,FLCN,PIGC,NKIRAS1,EPHB6,B2M,EIF1B,ISG15,SPTAN1,CHMP1B,ZBTB16,ACHE,LTBR,RLIM,WDR83,CX3CR1,JPH4,EI24,AMACR,TWIST2,MRPS26,DPEP3,ARG2,TFB1M,FXN,GABBR1,FBXO22,SNRPE,HFE,SAMM50,CEP85,EHBP1,PPP1R11,MYH2,TM9SF1,CSTPP1,PTEN,PPP1R12A,CDK17,CIMIP2C,PAPOLA,SYBU,BTG1,OLFM3,CDR2L,BTG3,ERRFI1,GABRB3,AZI2,MIOS,CCN3,G0S2,TUSC3,DPY30,RMND1,ADRB1,SMAD1,RNASE6,PYM1,RNF152,SPSB1,UBB,ANAPC11,CWC15,TPPP2,PTPN11,AGR2,IL15RA,EMP2,CHAMP1,MLF1,TIMM10,GTF3C4,SH2D1A,AUH,DOK4,DNAJB4,SIKE1,GNB4,SPMIP8,TSNAX,OVGP1,MARCHF3,ACADSB,RERG,LRRC1,NDUFB5,COL1A2,ALB,HDAC5,CFAP91,RAD23B,CRYGB,GUCY1B1,MEA1,TBCCD1,TIRAP,AFTPH,DYNC1I2,SFT2D2,TVP23B,HNRNPL,RPS6KA4,PGRMC1,CNOT2,TMEM123,URAD,STAP1,BUD23,SUMO1,AVPR1B,POMT2,VGLL2,CHMP2A,MCOLN1,CHST2,RAB9A,FBXO31,PTAR1,YPEL5,CAP2,HTRA2,SERPINB10,STX1A,CDK9,ACACA,MAF1,AGK,TRIM46,GPC4,NQO1,PDSS2,MT1A,SCAMP5,ACSL4,THG1L,APH1A,CCR5,WDR37,ARF1,ADK,TEX19,GNB1,UHMK1,LGI3,FUT1,NUDT9,RPS17,TIMP3,IL12A,NUS1,LAMTOR1,PSKH1,PEG10,ANKIB1,PDHB,SLC25A44,RPS5,KLK3,TIMM23,CSH1,PRDM4,EMG1,CDAN1,TPPP3,FUNDC1,HRAS,RBM22,GALC,GLRX5,NDUFS2,MGME1,MAT2A,NUP153,TAX1BP1,HAUS2,BFAR,TRIM3,GTDC1,PTRH2,SPRED2,SELENOF,UGT1A1,MYL12B,CYBC1,MAP3K21,CNOT7,DNAL4,CCR7,INPP5E,CNOT6,BANF1,BCCIP,PDE7A,CREB3,RCHY1,SLC4A8,METTL6,SETD3,C1D,APOBEC3A,LYZL4,KXD1,CBL,CAPG,STARD4,PRDX1,UGP2,CYTH1,PMM2,COP1,SPRR1B,TBC1D5,OCRL,WNT7A,POR,LYZ,CD1D,DBT,CISD1,CDC42SE2,RABAC1,TRIB1,RTKN,PPIC,GFUS,UBE2D1,CLRN1,SLAIN2,BOK,TIMM29,CHP1,DOHH,BHLHE40,PPARG,LILRB1,IFRD1,CCDC181,FAXC,GFM1,ALKBH4,MRPL11,RPAIN,CLN8,ABCF1,SELL,RDH11,FAHD1,CCR1,UQCRH,TRAM2,F9,ICA1,RAB3B,EVA1A,CLXN,JKAMP,CYP2C8,B3GNT2,WDR44,ZFAND6,PSMD14,TRIM35,TMEM14B,TLR2,DYRK1A,CD274,DLST,BCAS4,NOA1,TES,RAB40AL,PRDX4,CARTPT,MYRF,BLVRA,CCDC65,SGIP1,FBXO44,SARM1,FABP12,TUBG1,HCFC2,MEF2A,TP53INP2,MYL12A,SFTPA1,OPHN1,GOSR2,DNAJC7,HNMT,GTF2A1,TANK,EFNB1,CYB5R4,DCTN3,PSMG2,ZNF436,CSNK1A1L,BET1L,LAMTOR3,CAPN2,SLC38A2,DSTN,RAB14,ALG11,CYP2D6,MRPL53,CD2,UBXN6,DDIT3,NDST3,ADH1A,OPRM1,NSG1,SLU7,SLC25A32,CD2BP2,SLC35E4,FTL,AGTRAP,RC3H2,DNAJC2,NDUFS6,GAS2,GPC1,STARD5,FUNDC2,GCHFR,SERTAD2,STAT1,RGS10,ETV6,MRPL51,FSTL1,PFDN2,CRYL1,SERINC3,FZD3,F10,CRTC2,UBE2K,DHRS3,LSM14A,TRIM34,CISH,G3BP2,MSMP,NDST1,RACGAP1,GK5,PLA2G4B,CGAS,DHRS1,NMBR,SKP1,LDHAL6B,ETFBKMT,COX16,PSMA4,UQCC2,MAEA,KPNA1,MRPS23,MORC2,LCP2,SLC35F1,DAAM1,RGS19,CLDN11,ADPRM,PLCB2,GDI2,MYD88,TMEM30A,HTRA1,PIR,CDK6,GZMK,GAB1,SERTAD1,CABCOCO1,ARF6,GABRA1,PPP1R8,PPTC7,SLPI,PYROXD2,DAPK1,ACTB,UBIAD1,TOR4A,ELOVL6,CYP2C9,GTF2E1,CLCN6,FRS3,TXNIP,DNM2,ERO1A,MTMR6,CAND1,TREML1,FURIN,GTF2H5,HSP90AB1,PGK1,TTLL10,SDCBP,LBH,IFIH1,ATP6V1G2,AIF1,GSTT1,RTCB,RGCC,SRD5A3,TAS2R16,GSKIP,PACRG,MED22,SLC25A10,VAPB,TFE3,GSTA4,MTERF2,AREL1,SLC6A4,RARRES2,HSCB,CCNF,RBP5,TULP3,BORCS6,POLR1B,UQCC3,SRPRB,RPL23,NR0B1,GCFC2,PITHD1,SYNDIG1,MTPN,HP,RPGRIP1L,HSPB1,GNA14,TIMM13,PFDN6,SLC35E1,GDPGP1,PRL,SLC22A17,SRP72,CCNA2,DPH5,WDR82,YKT6,LYZL6,CDC20,SLC51A,HACD2,CCSAP,DHRS4L1,CDK1,TRIM24,FZR1,PSMD6,TBC1D16,MTAP,KRTAP3-1,RPS29,PIGK,UQCRQ,RABGGTB,SVIP,SESN2,PIK3AP1,GJC1,CSGALNACT2,AKR7A2,PAOX,FZD6,USP30,CCND3,EIF3E,SMG9,DKC1,DCP2,EXOC1,YIPF5,SLC25A3,ATG3,THOC1,XPO5,AP5S1,RIMOC1,CHMP5,CTLA4,MVD,RNF26,STAC3,HS3ST3A1,PPT1,SAT1,COMMD3,MARCHF5,POLR3H,CNP,ANAPC15,CDCA3,ATPAF2,MPIG6B,PPM1D,CLCA1,SLC25A26,CD63,SEC61B,CLIC4,KLC2,CMTM6,RTP4,HACD4,SSBP1,NME1,CYFIP2,COL3A1,MXI1,BORCS5,KCTD20,PDCD4,BECN1,RPS9,PNPLA4,LMO3,GMPS,ACKR3,KRT8,PDYN,RCE1,RNF8,RBMX2,GLO1,TIMM8A,BZW2,ASB3,CD28,SLC18B1,NUP62,RPL35,MPV17L2,IRF1,STK16,SOD1,MAMDC2,FOXP3,IDO1,APOBEC3B,ARL11,GSTCD,SAYSD1,LYPD6,TESPA1,ACTR3B,SUFU,RING1,TMED9,MED27,MCMBP,NUDT19,TCOF1,GNAQ,DCAF8L2,RPS14,CYGB,VAMP8,SLC25A14,ODAM,PLN,API5,WBP2,MGST3,VASH1,ORMDL1,TBK1,FBXO11,SNAP23,PAPSS2,CERS6,CXXC1,ATG9A,TXNRD1,CTNNB1,MPV17,ILK,IQSEC1,FBXO7,SNAPIN,CDC37L1,IRF7,VEGFC,RINT1,MCL1,ASIC1,SC5D,RETREG2,SYNJ2BP,CCDC85B,ESD,AP2M1,MOSPD1,POLR2F,E2F4,PPFIA2,IFT172,PATE4,PCCB,ELMO2,GPX4,MT2A,SPC24,SNAPC2,APEX2,TNNC2,HMGA1,RGS6,SLA2,DHRS7,SSR3,TOM1,TP53,RPL23A,CTSC,STAU1,ASRGL1,PPY,TYW3,VPS26C,TMEM45B,WDR6,UBASH3B,ISCU,PGAM1,MPDU1,CASP4,SIGLEC5,GJB1,NIF3L1,IREB2,OSGEP,TMX3,MTMR12,SNX1,ELP3,PYDC2,PDE1A,TSSC4,STARD3NL,NDFIP1,BPGM,PTS,CD151,MME,CD3G,BTBD10,PEX5L,PPIH,BPIFB4,RBBP7,CLEC7A,MIA2,FMO1,LURAP1,MATCAP1,MGST2,BAD,BARX2,JPT2,EIF4E,RANBP6,APBB3,LEP,SDR16C5,TCP11L2,COX17,ZC3H14,CLP1,LRRC8C,SYT4,RPS15,HMGB1,CCDC106,TRIM6,FBXL19,PLAA,TENT5C,TP53I3,SELENON,GLE1,YIPF3,TBC1D4,TECR,PSMB11,TLCD4,CNOT6L,SETD4,TMSB4X,SKIC8,HBEGF,MAD2L1BP,GPRASP2,SSNA1,TMEM160,RIOK2,COX20,SGTA,FGF1,IER3,PTGDS,GADD45G,FAM193B,SRSF8,MRPS18B,IDE,TAPT1,RRP7A,B3GALT2,TAF5L,PCYT1B,RPL27,SEC14L5,LGALS8,ADCY2,CRLF3,SEC22C,EIF2B3,HBM,EIF1AD,DTL,IK,ADRM1,GDPD3,TGFBR2,GAPDH,DERL1,FGL2,TRAF6,TGFB3,RPN1,CHST10,MTHFD2L,KCNS1,DXO,KIN,COX7B,SKAP2,PICK1,SRP14,CCNB1,ABCB1,BOLA3,NDUFAF4,PLSCR3,UCK2,TMEM190,SMUG1,RPS26,HSD17B6,QPCTL,SUCLG2,TERC,AMELX,PSMC3,VPS26B,TRIM23,SIPA1L1,RUSC2,UBE2L3,STK38,TIMM17A,SSH3,PKIB,NEK7,HYAL2,MPHOSPH6,RPL37A,MTM1,NDUFA2,SPTSSB,TMEM168,MIF,CDC7,SRARP,PPP1CC,NAA15,FAF2,RCCD1,NRGN,SOCS3,CCAR2,RBM42,JADE1,STIM1,LIPA,ATP5F1E,SLC31A1,EGLN3,NUDT18,APOBEC3H,RPSA,LSM4,SNX24,FMC1,INMT,MYBL2,VPS26A,SEC61A1,FOS,HEXIM1,TOPBP1,RDH10,ABCE1,STARD13,B4GALT4,AANAT,USP6NL,RFLNA,MAP3K3,NCKAP1,RAP1B,TOR3A,SMAD9,FERMT2,CHPF2,CCDC186,PSMB4,MGARP,TMEM39A,UNC119B,EIF4H,RPRM,BACE1,TNKS2,IRAK4,HEBP2,CBR3,CRBN,H2BC17,PMPCA,SPCS3,CYB561D2,PEBP1,PHF23,MTG2,IRF3,VAMP7,RPL3,PHB2,GLT8D1,AATF,KATNAL1,AMT,AIF1L,HNRNPAB,MAPK10,TPD52L1,LDHB,ACSS2,METTL15,MRPS18C,DERL2,RAB6A,TRIM22,DRG1,TNRC6C,THBD,PIGW,TMT1A,RSAD2,SEC11A,CDC23,MGAT5B,EMC1,HSH2D,ATP5F1A,UBE3A,ROPN1B,POLR3B,RAB11B,SCPEP1,REEP4,MRPL33,RAB32,S100A6,PSMD1,GMPPA,CACNG3,FGF13,ILDR1,CDKN2D,OLA1,PDF,PGAP4,CDKL2,RBM3,ELMO1,SERINC1,RUVBL1,FBXW11,C2CD2,GABARAPL1,FUT8,MTRF1,SOS2,SYNGR3,COMT,ELOVL3,CAB39,REEP6,NLRP9,NEDD8,PABPC1,MOXD1,TCP1,LST1,LRRC8D,TYMS,CXCR3,SLC25A24,SLC25A23,GLYATL3,HSD17B1,WASF3,LCA5L,DLG1,ZNF593,LZTFL1,SOX2,DCUN1D3,SIGMAR1,ALOX5AP,PRKCA,OSTM1,NSMCE3,DAG1,FKBP1B,RPL31,GPR137,ABHD5,WDR11,COX7B2,SNAP25,ASB1,ITM2A,NDN,PARD6A,RIC3,PREPL,ATP6V1E2,LIG3,PDAP1,PLG,ZNF397,XAF1,ATP6V1A,RNF182,CHST1,CLPB,ERLIN2,CCHCR1,G6PD,KCNIP3,UBE2V1,GFPT1,ATG101,COPE,SPATA2L,CDC73,TERT,SLC2A1,PSMC5,GPR15,TMEM59,CMPK1,CYB561,ITGAV,ATL1,NDE1,PPM1G,GTPBP1,MYG1,CCNI,ST3GAL1,TMOD3,ZBTB14,ATP6V0B,PDE2A,SQSTM1,MPP1,CLTRN,MRPS16,BCL9,DCK,SCG2,EEF1AKMT3,GSK3A,SLC25A21,TFCP2,CAMK1,IL1B,SLC35C1,DNASE1L1,RRAGA,FKRP,FMO3,CRABP2,LIN7C,MAGED2,CHRDL1,BCL2L1,SLC11A2,CDC42EP2,FGF22,RPL24,CDH11,ANKRA2,PIH1D1,INPP5K,CSTA,NAPG,PYGB,RAB39B,RPL18,ATP2C1,BPNT2,FKBPL,ACO1,MTDH,ELK3,SYN3,GHITM,CARS1,VIRMA,CRADD,RAB5C,BRAP,GPX1,ARFGEF1,PPFIBP1,PEDS1,RHOBTB3,PRKCB,SLC25A28,RAB35,CHCHD3,TRAPPC3L,RND3,MMP28,CMTR2,SULT1A3,SRSF1,SORD,COMMD6,ARMCX2,TM4SF20,STX12,CNIH1,MMD,IGFBP3,CTNNA2,NKAP,AVL9,SLC35A5,PHACTR1,DES,AAMDC,DHRS4,XPO1,LYPLA1,SLC39A13,ATP6V1G1,SEC23A,SPMIP9,ARGLU1,PDIA2,CERS2,TFG,SRC,PPP5C,PLD3,ZC4H2,CD1A,DIO1,JAK2,NTF4,TMEM209,SEC13,DSTYK,RHOH,SELENOW,GMNN,TRAF3IP3,TMEM11,NDUFA4,CA2,RPS10,LMBR1L,GPAA1,RAB27A,KCNH1,METTL21A,ZNF322,BTF3,STX11,MRPL50,UCKL1,SCN3B,BOLA2B,AGPAT5,HNRNPF,MTRES1,RNASEK,LMNA,WDR19,RNF10,FABP7,CXCR4,GNAI3,SDS,DFFA,NTMT1,DMTF1,MKKS,DDIT4L,KIF1C,ABCB9,NFKBIA,SFTPC,LAMB2,EEF1G,VWF,MT1X,CLIP3,SFRP4,CAPN1,ETNK2,PSMB7,SLC35F6,RPAP2,PHYKPL,PLAC8,CEP70,TRIM5,CASK,TMOD2,MOV10,SMAD5,VPS28,VCPIP1,COQ8B,AQP11,B3GALT4,MIR9-1,CD1E,RPS12,FTHL17,WDR77,COX6B1,SLC35D1,RPL27A,CMA1,GGH,CENPL,YES1,TRIM37,GNB1L,ARL4A,FBXL3,CREBBP,ID1,TRMT5,SKA3,ACER3,VTI1B,MTRNR2L3,EIF4B,MRPL22,ITM2B,NUDT5,VDAC2,HSD17B8,AKAP14,IDH3A,RNF181,RAP1A,URM1,ABHD4,SERPINA1,MRPS21,ECD,OTULIN,PLAAT5,USP13,SELENOK,PIP4K2C,DNLZ,SYNGR2,BCAP29,THNSL1,DISC1,PPP1R1A,USP3,POLDIP2,MFAP3L,PABPC1L,SAP18,CITED1,SEC22B,IL2RG,SH3GLB1,CPLX2,FKBP8,MRPL13,TPD52,PTPN1,ACOX1,RGS1,COX7A1,IVNS1ABP,NME4,NSFL1C,HCRT,PLS3,TRAF2,ATP5PB,PGS1,MAP4,MAP3K12,BCKDK,SSR1,TOP2B,CDK20,HS2ST1,MT1E,PGAP3,AKT2,CST3,SLC35G2,RETN,LACRT,RGS5,KCNIP2,RNF5,COQ8A,NUP42,CD46,MALSU1,ANAPC16,NFE2L1,FASTKD5,HGS,TRAPPC6A,CLSTN3,GRIA2,OS9,RAB33B,FGD2,EIF2B2,ERP29,DPH6,NOB1,SASH3,ETF1,PNO1,VCPKMT,MMP14,SLC25A4,TRIM15,SNRNP40,KCTD10,PPP3CA,RPL10A,UMPS,HSP90B1,STK4,ENC1,SMDT1,SDHB,ATP5F1B,FAU,CRMP1,DELE1,POLA2,GJA1,ZDHHC15,CD2AP,YAE1,MRPS9,EXOSC1,ADIPOQ,EWSR1,SELENOO,FGF3,AR,NRSN1,EGLN2,PARP11,GTPBP8,PCSK9,CPNE1,MS4A7,KCNJ11,IDH2,ATP8A1,PPAT,KLHL12,SMYD3,KHDC4,AGAP2,CIAO1,PAK5,SNX11,POLR3GL,NUCKS1,SERPINC1,CDKN2C,HSPB6,RNASEH1,PLSCR1,TMEM147,TNNI3K,MCPH1,LASP1,CEP57L1,METAP1,WBP11,PLEKHF2,TOB2,PLAAT3,CTNNBIP1,PRSS23,ACOT6,C2CD2L,PPP1R3C,TMEM266,KIT,CPLX1,DOK6,ZBTB6,MPG,ACTR1B,ADRA1A,MARCHF4,EDEM2,HS3ST1,NMI,DDAH1,RSRC1,SLC35B4,NFE2,HSPE1,NDUFA12,TTC8,FCGR2A,SRXN1,DCTN4,OLFM2,NLGN1,NMRK1,MPC1,THBS3,NEK9,ADRB2,SMNDC1,CYP26A1,PSMB3,ABCC5,SMPD2,RPIA,CFL1,AP1G2,CMC4,COX11,AHCYL1,MRPL17,DIS3L,MT1M,JUP,BIRC5,AGA,RASGRP2,SYP,RPS3,GIMAP4,MNS1,STK3,DSN1,ELAVL4,PKP4,FOLR1,NSDHL,POLR2C,ORMDL3,REXO2,ACAP2,VRK1,HEY2,LDAH,SCFD1,RBFOX2,TMX4,IRF4,NUDT3,DNTT,PNRC1,WRAP53,ACTN4,CLU,HNRNPA2B1,RNF144B,CLLU1,SLC25A46,MIR638,UAP1,PPP1R1B,RAB23,PKIG,UBE2A,GABRB2,RAB22A,ARRDC3,SVBP,EED,IL23A,AHSA1,CYP2C18,ATRAID,LMAN1,UFL1,HTR2A,SH3GLB2,RNF41,CALU,COIL,CLVS2,KLHL25,TAFAZZIN,DGCR8,FAM110B,SLC17A5,GGTA1,TIMP1,GMDS,NDUFB6,POLR2L,SNX33,PAX6,PEA15,TRIQK,LPXN,SPIN3,NDUFAF2,UBE2F,LARGE1,TSN,PCBP4,PIP4P2,TXNDC12,PRKCE,TMEM95,OAZ2,HUWE1,SNX3,OAZ3,TSSK1B,RHOG,FGF16,BLOC1S5,PDRG1,MBLAC2,RAB30,TMEM88,SMAD4,APOBEC3C,POU5F1,CHN2,FHOD3,GSTK1,SCHIP1,CIPC,APOBEC3F,RNF146,NREP,UCHL3,CFAP68,TOMM6,CPLX3,PRKACB,PNMA1,SLC25A45,STK11,RAB2A,KIF3C,UNC45A,ABHD12,GCLC,DNAJC1,ACAT1,CDC16,GTF2I,UQCR11,TIAM1,BET1,GPX7,NOP58,ADCY3,SART3,NUBP2,EIF1AX,EPHX1,KCNQ5,MIEN1,TMEM199,GRAMD2B,MAPKAPK5,MAP1S,CDC42,VEZT,CAV1,SCD5,CSNK2A1,SERPINI1,UBL5,PSMA6,OXCT1,PGPEP1,ZNHIT3,TXNRD2,TRAPPC10,RIMS4,TPST1,RPL26L1,ATP6AP2,SSBP2,OPTN,CPT2,MTHFS,ETFRF1,SPG21,TMEM74,CSNK2B,PAQR8,SPHK2,GRPEL2,USP2,TNNI1,HSPA8,PELI1,FEM1B,DUSP18,SPPL3,GPR37,TOX4,NPM3,DOLK,DDX42,NEO1,FCHSD2,PLEKHJ1,POLDIP3,COG1,CDK4,OAT,LYRM2,FEZ1,COX6A2,DUSP22,PIM2,COPZ2,MOSMO,ZMPSTE24,NUP37,FABP4,ALKBH3,PTGES,GNA11,FAM98A,ROCK2,YTHDF1,ELOVL1,BATF,KLF12,GAL3ST4,FLOT1,ASB7,TSG101,PGAP2,PPP2R5E,TDP1,PREP,RAB4A,SESN3,PCSK2,TADA1,LIPT2,VLDLR,C9orf72,SMN1,PYCR2,SEC62,UBP1,CCL5,ARB2A,TENT2,HINT2,SMAD3,PIK3R1,RTN4,RTRAF,RSPH1,UCP2,CHCHD2,TAPBPL,ASZ1,HINT3,MTF1,CTU1,GNAZ,EXD2,SACM1L,PSMA1,GLYAT,SLC32A1,NRP1,BHLHA9,ALPL,CSNK1A1,ITK,EMX1,RRAS2,CDIPT,KLHL22,FAM3C,CYP7A1,WWP2,NOTCH2,LYAR,MRPS34,APOO,SYNRG,ATP5F1D,SPP1,GRB10,CFTR,APPBP2,CUL3,OPA3,RMND5B,SELENOT,TSPAN15,CMBL,ACADS,RPLP0,GALE,FAS,EDEM1,GLTP,CYB5A,MRFAP1,PSME1,ELP6,GMPPB,CCDC42,LSM3,LHB,GSTM3,CD36,PTHLH,LGI1,HERC3,STAMBP,ITGA2,GK2,COPS4,GSTO2,IER2,NUP35,ISYNA1,KPNA2,BTG2,TBCE,USP8,AKAP1,ADH1B,SCLT1,GPBAR1,CFAP90,PHF7,TMEM167B,STAMBPL1,LUM,TRIM21,BRINP1,LPAR2,ACVR1B,KRTAP8-1,MIR29A,SERPINA3,DNAJC3,TDRD7,SHC3,EDEM3,GLCE,IP6K1,PRELP,TPH2,ZDHHC24,DVL2,CERK,DEDD,PTDSS1,HSBP1,SP4,DBNDD1,RNF11,ARCN1,CPNE2,CYP4V2,GABPB1,SNRPD1,CYP1A1,MRPL18,NPR2,SNX20,CCT5,ATAT1,FERRY3,MECR,OGN,CXCL1,KLK6,TMED4,FAXDC2,GINS4,NPC1L1,UPK1A,CDC42SE1,TRIM44,SLMAP,NDUFV2,ZDHHC16,SHMT1,ACAA2,MYLIP,CCSER2,MGAT4A,NETO1,ATP1A2,AKR1C2,PICALM,SNX14,TRAPPC3,RND2,LAMP5,CDKN1B,AGGF1,G2E3,GALNT12,MEF2B,GLRB,GPD2,MOB3C,EXOC2,CHCHD1,SDC2,SMG5,ECHDC1,SYNCRIP,PRELID1,HINT1,RALGAPA2,FAM162A,CRYGD,GTPBP2,TXNDC17,CIRBP,SEMA4C,EIF4E3,MID1IP1,LARP4B,DDX1,MFN1,YWHAG,SNAP91,EID1,RNF122,SSU72,TENT4A,LORICRIN,RAD21,RBM27,AGAP1,NCKIPSD,ACP2,INPPL1,POP7,TMEM38B,CETN2,FCER1G,SLC6A3,PDE1B,IZUMO1,MRLN,PRRT1,MACO1,ATP1B3,TNKS,CRYAB,RBCK1,CCM2,CALML5,TRIM63,MIR29C,SEC63,TUFM,APEH,CENPP,FEM1A,NCALD,FITM2,DRD1,PCYOX1L,RPL8,PFDN1,IPCEF1,OGG1,NKX3-1,TTC4,MRPS18A,CSK,ATP5MK,HIKESHI,CYP4F22,ZDHHC4,MOBP,PRDX2,UQCRC1,HNRNPA1,RAMP3,CD58,CYP11B2,SEC22A,DYRK2,HSPD1,POC1B,RNF148,CHKB,SNRPG,UBE2G2,DUSP1,DUSP6,TMCC1,MIEF1,SLC35A2,PHAX,THY1,GRPEL1,VMP1,TRIM11,FBXL7,CDK7,SLC25A20,BCL6,RB1,ATG4A,SFXN1,HYCC2,RP9,PXYLP1,RPS27L,REP15,TST,STUB1,OPRK1,TOR2A,PARM1,SLC35B3,TCIM,NDUFS8,TRAPPC6B,PIAS1,BOLA1,TPBG,PTPN4,RNF39,SOCS2,GON7,SELENOP,TRAPPC1,KCNG3,ASB11,TBC1D17,IDH1,B3GALNT1,CTTNBP2NL,CCIN,RPS11,AKAP8L,CDC26,TMCC2,TLR8,FKBP1A,CCAR1,RPL32,PGA4,NECAP2,VIPAS39,DUOXA2,MYO1B,CH25H,RANBP10,H2BC11,LDLRAD4,CXCL14,PHKG1,SPMIP10,SEPTIN7,RNF128,TNPO2,ELOC,OLR1,SENP8,MEIOB,MAP2K3,BEX3,CHID1,NTAQ1,HIGD2A,STX16,CFAP161,ACP6,PRPF19,HMOX2,TMEM14A,BAP1,PIWIL2,SLC39A7,OST4,PGR,LSM5,VKORC1L1,CLPX,ANKRD6,TMEM106B,TAB2,MAPRE2,STOX2,ABHD17A,LYSET,RPS27A,FAR2,EMC8,TGFB1I1,ETFB,TAF10,CCT8,DIPK1A,PHF1,ZDHHC14,ARHGAP21,MTMR2,PPP3R2,PSMB6,USP15,TRAPPC13,RIGI,SPOP,IFNAR1,NECAP1,TMEM59L,CTSA,FADS2,MLF2,DPP4,TMED3,ISG20,RNF167,GCC1,EIF2B5,VTA1,STRBP,CTNNA1,CDO1,TRAFD1,KBTBD6,CTSD,RETSAT,TBC1D24,ZMYM2,GPT,TOP1,UBXN2B,ACTMAP,RPL4,ZNF622,RPS2,RAB8B,PLEKHF1,SERPIND1,KHDC1,SHOC2,LILRA3,MAP2K1,HNRNPD,CSTB,CA8,AGPAT1,SERPINA5,PSMC4,SNTA1,EP300,TMEM87A,UBE2N,SGMS2,RGMA,PET117,FKBP14,TESK2,HBE1,PLAGL1,RALA,TUBA1B,LAPTM4A,GNPNAT1,PDCD5,PADI2,GYS1,PEX13,LECT2,AKR1A1,GANAB,CNPY3,NXT2,PEX26,RBM18,CX3CL1,STX8,AP1AR,GPR89A,ALDH1A3,CHMP2B,PPM1B,CD40LG,SLC25A12,DCAKD,ATP1A1,MAP1B,HILPDA,PKNOX1,EXTL2,CNRIP1,UBE2V2,LYNX1,MCM3,HSPB8,TIFA,ATP6V1D,SWAP70,FAM161A,USP5,ELK4,TACO1,PCK2,BAX,ZC3H15,TXNL4A,PHKB,ETFA,TESK1,NAPA,SYK,SFTPD,FARSA,TMT1B,HEBP1,PIK3R3,HCLS1,TAMM41,RAN,FKTN,POLR2D,KLF9,ZNF365,AP2S1,FXR2,ENY2,CCDC22,HSPA13,MRPL12,TPPP,FNTB,CCND1,CFL2,DUSP19,DNAJB6,KRAS,COX10,GNPDA1,RASD1,MITF,FAM13B,ACTA2,ZNF175,XPOT,MRPL49,FBXL14,CYP27A1,TNFAIP3,MARCKSL1,PDIA6,RIMKLA,KCTD17,CTSB,PTP4A2,RNF7,RBM38,GSTT2B,DLAT,SNCB,PRKD3,CHPF,PSMC1,CMTR1,ROGDI,RBMS2,SULT1B1,FDFT1,TNFAIP8L1,TUBA1A,RABIF,SYPL1,TRAF3IP2,GGPS1,DNAAF10,TEX26,PCBD1,XPNPEP1,ADO,TESC,MRTO4,SMURF1,MRPS33,SMAP2,MTRNR2L7,PPM1K,IL2RB,LDLR,AP1S2,ANKRD34B,HPCA,NDUFA5,RPL35A,UBL4A,TSC22D3,SPTBN1,PPIL4,EMC10,AIP,BLOC1S2,HSD17B3,RIMS3,FBXL4,SHC1,KPNA6,CCDC134,RPS7,PLA2G15,RGP1,EFHD1,IFI6,CNN3,FATE1,UBE2S,GTF2IRD1,AAMP,HNRNPDL,CDC123,SERPINB11,BEND5,COX14,ANXA7,IFI16,TFPT,EEF2,SFXN2,ARL6,COTL1,VEGFA,NAA11,TOMM70,RMI2,NOL12,PAPOLB,FEM1C,IL1A,MT3,CYP3A5,MRPS7,MRPS17,CCDC90B,GRIA1,RNF103,MSN,MACIR,CASC3,CNOT8,MIR21,ZBTB33,RPL28,PPP4C,PDLIM3,GLOD4,DNAJC24,HARBI1,FUT9,CPEB1,ADD1,CNDP2,ESYT1,CD9,ARL4D,FBXW7,DDX39B,RGS7BP,NRSN2,CARHSP1,KIAA0513,EEF1B2,ZNRF1,RHOBTB1,TEX264,CAMK2G,BORCS7,MMUT,ST3GAL2,SDHC,PHB1,MMP9,ATG4C,KIF3B,EXT1,MAT2B,CCDC3,SIX5,SELENOM,DCLRE1C,PMAIP1,ZMYND19,RAB13,UPF3B,SCAMP2,ALDH1L1,DCUN1D1,CCDC47,SMC4,DESI2,SEPTIN6,ST8SIA5,CHST11,MYC,SPCS2,COMMD5,STXBP1,PTPMT1,PTTG1,GGCX,ACP5,PDE12,SYNGR1,HPS6,RPL13A,OSBP,RDH12,TAX1BP3,PID1,PHYH,KLK9,P4HA2,GOSR1,FGF10,IRF9,AQP3,SSR2,ATP5MC3,RPL22,ARHGEF6,CLDN14,BAK1,ZNF207,TFEB,WDR20,NRBF2,TAF1D,ARL6IP5,RAB31,BRI3,EIF4A2,MTARC2,SLC25A5,PPP1R16A,DNAJC8,ARMCX1,ARL14EP,GARRE1,CYP2F1,FUBP3,TLE1,COX6C,CEP97,JAKMIP1,FN3KRP,TRAF1,GALNT2,RER1,SHISA2,XRCC5,RHOU,KLHL9,SRSF10,E4F1,ALKBH5,JPT1,HSPA5,DNAJC5,PDLIM4,EIF2D,H2BC9,IFI27,GOLGA7B,DHRS7B,PSMB2,SMU1,DEK,HACD1,FKBP2,KRTAP4-1,RBPJ,PIWIL3,CPTP,PTGFR,FPGT,MSRB3,AKR1E2,SIAE,FGR,PIWIL1,WASL,RPAP3,PI3,MLC1,NIPA2,CYP3A43,EIF4EBP3,ARHGAP19,UBE2W,AURKAIP1,NFKBIB,MARCHF9,KBTBD13,NUDT7,MDM2,UCK1,PYCR1,USE1,FMO2,LHFPL2,RPE,IMPA2,LACC1,TMEM108,NABP1,VAMP1,MIR223,CBX7,GHRL,USP38,MIR181D,GSTO1,RPL29,MIRLET7I,MIR214,RFXANK,EGR2,RNF126,IFI35,GPSM3,RAB3C,DYNLT3,RAP2A,RPLP1,NAA50,RWDD3,GSTM5,STAT5A,CXXC5,HAPSTR1,CREB3L4,SIRT7,TRIM52,KDELR2,SLC25A51,PLCXD3,AKR1B1,SPOCK1,WSB1,SV2B,EIF4A3,PSMD10,CHST7,CTSK,SAR1B,HSDL2,CDCA7L,S100A11,LEPROTL1,LIX1,TXNL1,CLDN8,PIK3R2,RPL17,DRG2,EXOC8,FBP1,SPTSSA,CGRRF1,CATSPERZ,CASP12,SPSB3,ISOC1,MRPS11,DMPK,PRCP,ACTL9,ENO2,TRIM10,TLR1,KLHL3,VAMP3,MSH6,LRATD1,MAGEC2,PABPC5,PFDN5,MAP1LC3B,NUDT4,EMC2,IMMP2L,FAAP100,CACYBP,CKB,PLEKHO1,SNRPN,MRPL40,TMBIM1,UBE2H,DNAJC10,TNFSF13,ADIG,RHEB,SPMIP5,VPS33A,PPIG,INPP4A,GPNMB,MARVELD1,DLG3,CAV3,REEP3,RNF14,MTX2,APOC2,SMCP,PIK3CG,SLC25A39,HENMT1,PYURF,YIF1A,PITPNA,PSPC1,LANCL1,TMEM177,CFAP61,ADSS2,SNRPD2,GNMT,UBE2D3,STOM,ISCA2,SPMIP6,SAV1,JAGN1,CPT1B,CSGALNACT1,UST,NCBP2,RNF187,DUSP10,DENND2D,TRIP4,SRPK2,GDE1,RPL9,FCMR,FAM241A,CRIP1,FCGR1A,GSTM4,PDE9A,LAMP3,LSM2,ARHGAP1,EGR1,VPS39,RGN,VPS4A,LIMD2,PAFAH1B3,NUDT12,PMP2,MYOZ3,COPS7A,FAM83B,KLHL7,RAC2,AOX1,DPM2,ARMC6,OSBPL8,PAQR3,TRIM8,SGMS1,RRM1,DDT,LRRC8A,PDP2,RPL15,RPS20,DNPH1,PTPN5,SELENOS,GEMIN8,LCP1,CENPM,WDR45,NR4A2,TMEM106C,YWHAH,DUSP21,UBAP1,CHI3L1,SURF4,DHX9,MCCD1,SNX12,MMADHC,TMED7,MAP1LC3A,PIP5K1A,TRUB1,PAK2,ROCK1,NUDT1,EIF2S1,ADCK1,UBE2I,TPT1,F2,CRHR1,GNPTG,TAF7,DTWD2,PDHA1,DDRGK1,RHOB,OTULINL,DHPS,DDIT4,SKA2,PRMT5,KLF4,CDK5R1,CMC1,CIBAR1,PHYHIP,NR1I3,DDAH2,HIGD1C,TMEM174,CTBP1,DNAJC30,KRIT1,NDUFS3,NDUFAF3,ANP32A,PROM1,PPP2R1A,HAX1,ARMCX3,COA4,ST8SIA4,ST3GAL5,ELOVL7,TBC1D13,ITGB5,PBLD,FBXO9,HBA1,KLK5,PSME2,TRAF7,CHMP4C,SNX10,MAEL,TFRC,ILF2,ARHGAP5,EIF3G,G3BP1,AZIN1,SRSF7,SRFBP1,ZCCHC7,CNTROB,NDUFB7,SEC61G,PDIA3,PQBP1,FMOD,NDUFC2,EIF2AK2,PXMP2,NUFIP2,FBXO3,PPP2R2C,CDNF,PAFAH1B2,STARD7,IL13,CYP17A1,GLIPR1,DBH,MRPL34,TMEM100,CDH13,GAS8,PYCARD,MEF2C,BOLL,GGCT,ARHGAP15,FHIT,FAM8A1,CBR4,TBCEL,MZB1,BNIP3L,MAVS,PPM1M,SLC1A3,SMAD2,MYH1,RNF139,PCMTD2,NOVA1,FBP2,CYBRD1,NGRN,LRP6,CCT2,KLHL1,CREG2,RAB5A,UBTD2,NLRP3,SLC66A2,ALG2,FAH,GNB3,MRPL47,CCR3,TRIM27,PKIA,EIF3D,TNFAIP8,NGB,SCG3,DLX1,GCNT3,MRPL36,CYP11B1,RETREG1,IMPACT,HEXB,BST2,FLRT2,AQP4,TUSC2,CACNB4,TAPBP,UQCRC2,NEK2,PTN,NAA35,GAPT,ARMC1,GALNT1,F7,TMEM33,CALY,RGL2,NAA30,ATP6V1C1,PSMB1,FGF17,COQ10B,HECW1,MBD3,LBR,TMEM126B,BAG3,LINC02914,WNT2,TIMM21,AIPL1,EIF4E2,MRPL57,CYP4F12,GSTP1,GPAM,KRR1,COX6B2,SPRN,NUDCD3,ZNF687,DNAJC25,PSEN2,HAS3,FLRT3,TBC1D25,SPON1,STBD1,TMUB1,AKR1C1,KARS1,USP14,ILVBL,PML,TWNK,WSCD1,CEND1,CRYBA1,TNFAIP6,FAM91A1,PAIP2B,RXRG,CSRP1,GCA,BIRC2,HADH,ASTN1,SFN,PNP,ASPM,MAPRE1,TRIM62,FAM89B,ATP5MG,ARPC2,NKIRAS2,PAFAH1B1,ARPC3,ERLEC1,RBFOX3,GABRG2,KIAA1191,MYORG,NXT1,CIDEB,CUL2,EDF1,RILPL2,CD209,PRDX3,NEURL2,STAR,STK26,RPL39,MAD2L2,ACBD6,UFM1,PSMA2,DUSP26,GIMAP2,RAB28,IPO8,EMC6,STT3A,HYPK,NPY,PSMD4,RPS4X,RETREG3,ZFP64,NEFL,IGF1,TRIM36,TMEM179B,RGMB,RAB11A,TUBB,RNF115,NFE2L2,GDAP1L1,PIK3CA,NPC2,EEF1A1,EXOSC3,PRNP,TIMM8B,CYTH2,FRMD8,CLVS1,FAM210A,EPS8,ABHD13,BCL10,CHMP1A,FIG4,TMBIM6,CAMLG,NIBAN2,NT5C2,ATAD1,TNFSF12,NUDT16,DROSHA,CHCHD4,ZCCHC17,MGAT4B,GSTM2,CYP2R1,PIWIL4,ADD2,NUDT2,RBP2,CD14,ARF4,GLUL,SPRY1,DLG4,BRCA1,SNN,METTL2A,ZCRB1,TRIM54,TNIK,DTD2,CXCR1,SIVA1,SLC37A4,ACTR1A,STK24,TLR4,DCAF5,PLEKHA8,COPS2,CD1C,RMDN3,PPFIA3,SLC38A9,AKT1,TYW5,CRHBP,GPRASP3,TRAPPC14,RPL12,DNAJB9,CD4,LPCAT3,CRYM,PELO,PPP1R10,STMN2,FAM20C,MEST,ASB8,FHL3,TRIM68,TNPO3,RAP2B,YWHAZ,PARL,DEGS1,HHIP,CAMK2N2,PAK6,PPP2R5A,TEX261,IL15,GRAP,STX6,PRKX,PDE6D,SPACDR,PDCL,P3H1,ZFAND2B,NDUFB4,CDKN1A,S100A10,EFHC1,RASGRP3,DKK1,SLC25A1,TOMM20,AGO1,COA5,NBN,FIBIN,CFAP119,GADD45A,CREBZF,PPP2CB,CHGA,SNAP29,LANCL2,KCNA2,SRPRA,TNNT2,RPL10,TOLLIP,RPS23,DAPK3,STOML2,ENO1,SNRPD3,TMEM170A,TMEM50A,MRPL24,DYNC1I1,NTRK2,SEC61A2,TMEM117,HNRNPK,STAT6,CDIP1,FIS1,CRKL,ATP5IF1,ATP2B4,PFKFB2,NPTX1,TLR9,SEPHS2,ENDOD1,ACOT8,DCUN1D5,TMEM126A,PSMD12,LRWD1,LIMS2,HM13,LXN,CYTH4,TICAM1,SLC1A1,MAD2L1,XBP1,SDF2L1,PSMD7,PRR13,TCAP,KRTAP12-4,LRRC61,MDFI,LCMT1,ASMT,NDC80,EXOSC8,LDHA,CRYZ,FRZB,GPHN,ABHD14B,SSPN,STX17,DTYMK,FGFR1OP2,UBA3,MAN1A2,PFDN4,STAT2,CFAP418,TMEM165,TRAK2,DUSP9,TLR3,TBC1D10C,ENPEP,HDAC3,ANAPC2,SH3BP5L,ANAPC4,FASLG,STPG4,PDE4B,FCAR,APOBEC3D,AP2A1,CDC42EP3,ERLIN1,STRADB,SCYL2,PHETA2,POLB,RARS1,TOM1L1,MORN4,PDE8A,COPS7B,HADHA,MMACHC,TNFAIP8L3,RRAGB,EDC3,TNFRSF1B,GATD3,ENKD1,NAA60,CD47,SUV39H1,OCIAD2,ACOT13,OPRL1,CDK2AP2,CRTAP,RPS24,TMX2,ANP32B,ORC6,TFPI,HYCC1,EXOSC4,TRIM45,DNAL1,SRGN,AK5,ALYREF,PPID,USP46,TMIGD1,CAMKV,MRPL10,PRM1,MIS12,PNPO,TRIM29,CSKMT,NCDN,GNPDA2,RAB18,BAALC,BORCS8,BLOC1S3,CYP1B1,FCHO2,RNF121,CYB5R3,LRAT,UBE2B,EPHA4,BCL2A1,GABRA2,FANCG,SLC35E3,EIF3J,SAT2,PRKAB1,ARMC8,NAE1,FBXO30,PRSS37,COA1,HSPB2,POLR3F,NUP107,CYRIB,COMMD2,OTUD6B,AIFM1,NHERF1,NPPC,ATP5PD,ARFIP1,PIGA,NT5C3A,PSMA3,SLC52A3,CSNK1E,RAB33A,HEXIM2,DDX39A,CCDC69,OAZ1,PROS1,NOSIP,CYP21A2,RPS16,NUPR1,SNX5,EEF2KMT,DHX16,NDUFAF6,FAM83A,CACNB3,H2BC12,CCDC92,CATIP,MARS1,SDC4,YIPF4,KDELR1,EHD3,BAG2,C1QL1,GLRX,SLC48A1,SLC30A7,TSPO2,S100PBP,DNAJC19,TXNRD3,NANP,MRM2,INSIG2,IGF2BP1,KIF2A,SLC25A17,KICS2,WDR55,LCA5,CDC42EP4,RNF34,CD164,IRAK1BP1,AKAP12,CYSTM1,B4GALT1,S100B,SSX2IP,TAFA1,CDC5L,AKT3,SOST,GADD45B,GABARAPL2,PSEN1,GH1,CCNY,HECTD3,STX7,ABHD6,CSNK1G3,NOL7,PSMA5,PTPN22,LSM6,AFAP1L2,ZNF655,CLEC18A,PRKCQ,TOMM7,TOR1AIP2,IFIT2,SLC35A1,SPEF1,DCTN6,ATG7,MANSC1,RABL2B,MSRB1,SPATS2L,CCS,ZYX,GID8,DUSP3,TOMM40,TLCD3B,HEXA,DICER1,ATG16L1,GNPAT,IL18,RNF133,UGDH,UBXN10,MAP3K11,IL12B,CCL3,RAB3A,GRSF1,RBBP4,FEN1,IFTAP,TPM3,AK3,ECRG4,MAGOH,FAIM,NDUFB10,CDK5,TIA1,TMEM198,RAB1B,CDK5RAP3,STK38L,VPS18,UFD1,JAKMIP2,EHHADH,SLC38A7,RPL7L1,PHTF2,SIAH1,YAF2,CASTOR2,WEE2,GTF2E2,TP53TG5,TTC1,SNAI2,SERPINB9,MOB4,RP2,UBE2E3,CHIC2,TRAPPC2L,MUL1,ODC1,ARL5B,CEP19,CIB2,PAIP2,RAB9B,EIF3K,DDX5,NUF2,EHD4,NMRAL1,TSPO,CCDC184,BRINP2,PTP4A3,ERG28,TASL,ARFGAP3,GUK1,ARHGAP12,DYNLL1,DOK5,CHST13,CFAP298,VPS54,SDHAF1,SLC39A9,UBA52,SPEM1,MTCH2,AP5M1,CD59,DCTPP1,NDUFB8,SEPHS1,RCBTB1,SMG8,TKTL1,KLHDC8B,CTTN,TMEM115,SPINT2,GRAP2,RPL7A,SNIP1,TRAM1L1,PREB,BRINP3,HCFC1R1,IGBP1,TIMMDC1,ENPP4,SPR,ASPA,MECP2,TM9SF4,TDRP,RAP2C,POU1F1,RNASEL,KCNAB1,ZDHHC17,ST6GAL1,DENND6B,GKAP1,NGDN,TRMT11,ATP1A3,RNASET2,PSMB10,DNAJB2,IDH3B,FGF23,INSM2,EEIG1,SCG5,KLHL24,ERH,TAF11,GALNT17,CYB5B,YWHAB,CCDC172,TGFB2,KCNB1,CYP27B1,DCTD,B9D1,HMBS,TMEM50B,VDAC1,PIGY,TRAPPC4,SST,RGS2,PAXX,MRPL23,CFAP95,SRP54,TNF,PITPNB,RPL7,CHDH,GAL3ST1,BCS1L,WWP1,PEX3,SLC25A31,TMEM203,HBB,OAS1,SP1,FTH1,AASDHPPT,AZIN2,DECR2,OXSR1,CBLN3,IRF6,BICD2,FKBP10,TYROBP,RIOX2,BACH1,RANGRF,TNFAIP8L2,PPIB,TMED5,PPIF,CORO1C,LPAR1,COX4I2,SNRPB,JMJD8,TSR3,NME2,PLPP6,FBXO25,TF,MX2,HSD11B1,GJB2,NACC2,VPS4B,SPOPL,FGF12,RAF1,TLR6,SPATA4,PPP1R18,DAD1,CD248,ROMO1,MRPL52,S1PR4,GALNT4,POLR2G,SERPINB1,LITAF,CD34,ZBED3,ABCG2,MOB3B,MAPKAPK3,ATP5PO,TRIM26,BBS5,TNFAIP1,TUBB4B,NCK1,HPGDS,TMED1,HACD3,PTGES3,TXN,CDR2,ST6GALNAC3,LSM12,ATP6V0E1,SLC2A3,TMEM208,SNCG,TMEM127,IL1R2,B3GALT1,GNAO1,SLC2A8,BPIFB3,CAPZA2,SRM,PELP1,SH3BGRL,NF2,FAF1,RWDD1,INA,FTSJ1,ARL2BP,MAPK4,HNRNPC,CLIC2,GLIPR2,TOMM22,NLRP2,MRPL41,PSMB9,SYNGR4,NFKB1,GLT8D2,MDH1,BMP1,TTR,RIMKLB,PELI3,EIF2S2,MYL6,RANBP1,DRAM1,SKA1,ARPP19,VMAC,SYNPR,STC1,RPLP2,FGFR1,PRKRA,H2BC14,MIRLET7C,PLEKHO2,GOLGA7,MRPL9,GOLPH3L,CAVIN2,PSMB5,COX8A,SLC13A5,GAMT,B9D2,USP16,MAP2K6,HNRNPH2,DPAGT1,ALG5,FBXO32,RDM1,KRT7,ZFAND2A,RPS28,B4GALT3,BRMS1,RPL6,BGLAP,NLRP1,SDHAF2,MLLT11,CAPZA1,MGAT1,PRPSAP1,AP1M1,ST13,POMP,CNIH4,SNX18,MCAT,FAM20B,SCP2D1,TOM1L2,KCNJ8,CEP41,S100A8,TAB1,METTL18,CYB5R1,NLRP6,RIT2,MRPL20,FGF7,PSMD3,APEX1,CDKN3,CD247,DIPK2A,PPIA,SPATA2,SELENOI,PGM2L1,SNRPB2,MMAA,DIO3,CAMSAP2,OGDHL,CAMP,EMC9,SLC25A42,SLC25A27,NOP53,UBE2M,SPRED1,CD1B,MKLN1,BABAM1,PRICKLE2,ATF4,SDHAF4,CSE1L,CALR,SERPINH1,FAM136A,PIP4P1,IL6,SLC30A5,DYNLRB2,NR1H2,MRPS35,MCRIP2,SPCS1,SLC12A2,ATP5MC1,SNRNP48,CHST9,PRSS12,VDR,SOCS5,AQP2,RPL19,TOMM40L,NAIF1,ANXA4,VAMP2,UQCC6,MTA3,OCEL1,TRMT112,FA2H,IKBKB,GSTA1,BSCL2,MPST,NAA16,CNKSR3,LIAS,CAV2,JOSD1,SFRP1,GOLGA5,FZD4,TMEM196,HDAC6,SLC25A11,MZT2B,FAM107A,GPR85,MTG1,MRPS25,PACSIN3,MRPS28,TP53INP1,MX1,PHKA1,PYGM,HS3ST5,COX19,ACTR2,DPH3,SVOP,TICAM2,IFT57,LRRC14,GBE1,EXOC5,XXYLT1,TRMT10B,EHD1,CARD19,MAGOHB,COMMD9,RNF208,EXOC3,ACO2,PLP2,B4GAT1,SLC15A2,UBAC2,NOS1AP,FKBP4,TPGS2,ENTPD4,FAM168B,SOD3,SH3BP4,NCSTN,GHR,LYPLA2,VAMP5,PRKAG1,DEFB1,PC,COX5A,QTRT2,CCT7,UPRT,PRMT2,MAP3K14,ZBED4,CYC1,WDR83OS,TRAM1,PRDX6,PPP1CB,SLC23A2,STX18,PRRC2A,NDUFAB1,ATXN10,EEF1E1,HDHD5,GEMIN7,ORC5,CBLL1,PAIP1,METAP2,LAMP2,TMOD1,SYS1,CYP39A1,APTX,GASK1B,MSMO1,APOBEC3G,SRSF2,ESR2,COPS5,ST3GAL4,IGFBP4,GSTA2,LAMTOR2,TLR7,SUMO3,RAB29,C1GALT1C1,CETN3,GPX2,NAT2,TRIM32,UNC50,AK2,PSRC1,ARFGAP1,HSD17B10,ELOVL4,RPL10L,PDCD10,GAD2,SEC14L1,VPS16,B4GALT7,ZBTB42,ADAMTS1,COMMD8,ABHD2,LMBRD1,OTUD7B,SPECC1L,CRAT,IRF8,ABHD10,HMGCS1,CRY1,DESI1,COX4I1,RAB37,RPL26,HOMER1,TFIP11,EMC4,CTNND1,DDX4,OR51E2,TOR1B,EMILIN3,MRPL16,HERC4,RBIS,JAK1,TAGLN2,IRF2,ELK1,PLCB1,B4GALT6,FABP5,LRRC8B,TMSB10,FITM1,CNR1,PCLAF,GNAI2,CFAP20,LYPLAL1,TSPAN5,CFAP36,BUB3,CHAC2,RAB3D,SNX17,LRRTM1,IPP,THTPA,MIR17,LY96,SOD2,DMAP1,GLRX2,LSM10,OSGEPL1,HSDL1,DTD1,SLC8A1,STX10,MAIP1,LAP3,AKAP17A,STX5,VAV2,EIF5B,CHRM3,TMEM97,RGL1,CPE,NDUFA1,HOMER3,PNPLA8,BPIFA2,LGALS3,RB1CC1,KDSR,PCMTD1,MINAR2,RPS13,CHCHD6,RAB6B,C2CD4C,GABARAP,FHIP1B,PLA2G5,SLC41A3,CFAP73,EIF4EBP2,FBXW4,WTAP,SNX2,SRI,CELF6,SNX22,TMEM70,GORASP2,HSD17B11,PRPS1,NPSR1,UTP15,SERPINB6,MRC1,SLC7A14 |
| 6.098e-30 | -67.27 | ESR1 (estrogen receptor 1) | protein interactions | 2099 | 2322 | 888 | 19454 | 5460 |
EIF2S2,CSTF3,PPP1R10,NCAPG2,UTS2,TIA1,RPF2,RRP7A,SPOP,EIF3G,PRDX6,TWNK,BANF1,HCFC2,HSPA5,ZC3H15,KDM1A,SMYD3,NTPCR,CCNH,SUMO1,SPTBN1,E2F6,UTP15,SAMM50,ZNF326,SDCBP,WRAP53,COX4I1,NDUFB4,SYNCRIP,SLAIN2,SURF6,CDC5L,ILVBL,NR2F6,TMA16,CSNK2A1,ZNF24,ACOT8,CMSS1,RPL10A,TUBG1,MAN1A2,RPL3,MNAT1,KPNA2,TOLLIP,CEACAM5,IMP4,RBCK1,ZMYM4,ACTR1A,H2AX,PREB,TAF2,TAB2,IK,DNAJC2,ARPC3,GTF2F2,EFHD2,ATP6AP2,FBXO22,USP16,CXCL1,LDB1,DNAJB6,NSA2,RBM27,CHTOP,SPCS3,AKAP1,HSPA8,HDAC5,XRCC5,GNB4,STAU1,SSR3,HNRNPA0,DHRS4,NUP62,RPL27A,S100A8,ZHX1,CORO1C,ADGRG1,POLR2L,HMG20A,LYAR,EIF2S1,AFTPH,FAM98A,EEIG1,GSTM3,YWHAB,FKBP4,PDIA6,RUVBL2,PABPC1,RBM3,RPL28,CSTF2T,KIF2A,MSX2,MED9,PPIL3,MTA2,CAAP1,TRIM24,PRKRA,RTRAF,PELP1,SEC63,TECR,RPL13A,MGAT1,TXN,USP14,TUFM,NONO,AR,ATP5F1A,SEC13,TADA3,MTDH,SQSTM1,SIRT7,PNO1,AATF,SLC5A6,USP8,CERS2,EIF5B,EIF3J,HACD2,EDF1,FUT8,SNRPN,SAP30BP,IFRD1,NOL7,HSP90B1,CDK1,UBP1,AIFM1,H2AZ1,CAV1,G6PD,TOP1,POLR2I,RNF14,NFKB1,TOPBP1,DNAJC7,ESYT1,SLC2A1,HSD17B10,ZC3H11A,SLC25A10,MDC1,EIF3E,SNRPG,OLA1,HSPE1,PSMB9,YTHDF2,CCDC47,CASK,SRP72,RAD23B,ILF2,CREB3L4,DMAP1,AP2M1,RPL37A,SLC30A7,RMDN3,CYB5R3,EIF3K,PARP2,RPL19,RPL7L1,RBBP4,MCM3,OTUD7B,RFC5,CUL3,CFAP20,MYO6,NOA1,RLIM,CCDC86,WBP2,ATP5MK,UNC45A,G3BP2,PSMC1,NRDE2,MTX2,MYL6,HP1BP3,PHB1,LRWD1,OS9,ZNF593,SPTAN1,RPL7,CCAR2,NOP58,DPY30,MRPS35,CAMSAP2,RSBN1L,KDM2A,RPS24,UBE3A,JAK1,ANP32B,PLPP6,LAMB2,G3BP1,MAK16,MARCKSL1,SSBP3,AP2S1,EIF1AX,SF3B5,EZH2,PPP2R5E,CSNK2B,MID1IP1,SF3B6,DYRK1A,TXNDC12,SLC25A1,PSMB2,AKT1,SMARCA5,CDKN2AIP,MECP2,TXNDC17,ITM2B,BAP1,LIN7C,DDX46,WDR3,LEMD3,CYC1,KLF4,LUC7L3,TFIP11,TFB1M,HBB,GATAD1,RPL32,SSBP1,MRPS9,MYL12A,STX6,CAND1,KCTD3,TMED9,API5,E4F1,GAPDH,ELOC,TPM3,COX5A,MAP4,KPNA1,TAF9,LSM3,RPL24,SHC1,DHX9,SOS2,CLPB,GLCE,CSE1L,H3C1,RPSA,TP53,IMP3,SLC25A24,CDK8,RCE1,VDAC2,RPL10,ESR2,APEX1,NCKAP1,LRIF1,GADD45G,POLR2B,CBX5,CPSF2,PSMD1,HNRNPC,MYC,SERPINH1,RCL1,CXXC5,GADD45B,H2AZ2,CCT2,CIRBP,SF3B1,TAPBP,RPS28,EEF1G,UFL1,TMEM266,EFHD1,TOMM22,ATP6V1C1,CSNK1A1,EIF4B,NUFIP2,RBM5,ISG20L2,QPCTL,NGDN,YWHAH,DNTTIP1,XPO1,RPL6,BAZ1B,LAMP2,DDX50,CNOT2,MYO1B,EWSR1,GNA11,UTP25,PAK6,CCAR1,HNRNPF,USP30,EEF2,TUBA1A,DHX38,TRMT1L,RPS23,TAF10,APTX,NDUFA12,EIF2AK2,CTTN,GNAI2,VIRMA,DEK,CTTNBP2NL,TMOD3,ZBTB17,TAF5L,GGCX,AP2A1,ASCC1,SOD1,UTP23,PIAS1,KDELR2,SHOC2,AGAP1,STOM,SLC12A2,KRR1,MRPS23,MDM2,TOMM70,SUV39H1,RAB22A,FAM133B,SPATS2L,BRD3,NME2,IGF1R,PQBP1,TMEM50A,SMN1,PTGES3,CNOT7,EXOSC8,CCT5,POLR2G,RPS9,SNRPD1,CNOT6,VPS72,RSRC1,REEP4,TUBB,LGALS3,RPS29,ATF1,PKP4,RAB11A,NFYA,LSM14B,BRCA1,YWHAZ,MED10,FYTTD1,EMG1,CMAS,RGS19,YTHDF1,CYFIP2,SLC25A3,ARCN1,BRD9,RPL9,NUP35,HSPB8,HNRNPA1,NDC80,PDIA3,PIK3R1,MPHOSPH6,HNRNPD,DROSHA,SKIC8,CDK5RAP3,WDR12,ZCCHC9,SRSF7,FAM76B,SCYL2,SLC25A5,SSRP1,MSL2,RPS27A,ATP5F1D,JUN,ACTN4,RPL29,ANP32A,SART3,POLR2C,EXOSC3,PPID,RPN1,PSMC5,FKBPL,RPS3,SRPK2,SRC,SMURF1,GABPA,RPS17,MORF4L1,NR0B1,DNAJC10,RAP2C,NR1I3,EXOSC4,HNRNPH2,TMX2,MARS1,EIF4E,RBM22,XBP1,TRAM1,SLC35F6,HECTD1,HEXIM1,GTF2B,EEF1B2,DKC1,TMPO,RBM42,NKAP,DNAJC1,RPS16,IFRD2,MIOS,COPS5,XAF1,KARS1,CDK12,RPS2,SMAD4,MRPS18B,STX18,SLC25A11,SNIP1,FKBP8,SRPRB,KDM4B,ZMYM3,TMEM205,MTCH2,MRPL47,RAP1A,SRFBP1,SNAP29,TFRC,GTF2F1,SF3B4,FAM83B,PHF12,PPP5C,ATP5F1B,EPS8,MCAT,POLR1B,FTSJ3,H1-10,COX16,LAMTOR1,EP300,FOS,PYM1,HIRA,MRPS7,EMC1,CD59,CTBP1,RFX4,MAGED2,SDC4,HOMER3,SRSF1,CLK4,PGR,NT5C2,PPIB,MRPL9,CNOT8,PPFIBP1,RIOX2,HSPB1,DRG1,FOSL2,RTCB,TRIM11,DNAJB4,FBXO11,TOP2B,CCT8,HPCAL1,RPL18,ZRANB2,KDELR1,RPS20,UBE2I,PTEN,EIF4A3,STUB1,RPL22,YES1,ZNF622,KLK9,PPP1CC,CDC16,CASC3,LGALS8,ORMDL1,PRPF4,POLDIP2,NHP2,MBD3,RPL4,PFKFB2,SMC4,SGF29,GTF2I,DGCR8,NPM3,CNP,SIPA1L1,PRMT2,CCND1,CPSF4,RBFOX2,RPS14,RPLP0,ZNF574,CNTN2,MRPS34,LMNA,JUP,PWP2,SRPRA,HACD3,ETV6,SRP14,ZBTB2,AKAP17A,ATP5PD,PPP1R18,MPG,TLE1,ORC5,MPHOSPH10,EXOC2,MED21,SNAP23,DLG1,ZNF787,TFPT,PRDX4,MSH6,CNOT6L,RPS13,TOM1,THRAP3,TF,CTNNBL1,PAK1IP1,ING1,MTA3,TBK1,COMTD1,RNF181,MRPL49,SLC25A20,CLDN3,PIGK,RAN,CHP1,GNB1,TMCC1,MCM4,RBM15B,RNF40,TOMM40,NOP16,KLK5,SP1,LMNB1,WDR20,HADHA,THOC3,SKP1,LMO4,SUPT3H,WDR77,ADNP,MED23,ATP5PO,MYEF2,PPP2CB,SP2,CETN2,NDUFS8,ERLIN1,CACYBP,CGGBP1,RAP2B,TRA2A,WDR11,EIF3D,TRIM8,PRPF19,CD58,C2CD2L,TRAF6,ZC3H7A,ARGLU1,PPAN,MORC2,AKT2,TRIP4,RFC2,MRPS17,KCTD17,RBBP7,TRIM26,GTF2E2,NUP153,TXNRD1,GPBP1L1,CTSA,INTS12,CYTH1,RBMX2,SRP54,PRSS8,PSPC1,UQCRC2,STAT5A,GORASP2,CFL1,RPL7A,TRIM32,ALKBH5,RBM7,EXOSC1,MRPS16,LSM12,TRIM3,NBN,RBM23,WDR55,STK38,HDAC3,AIF1L,RPS15,CD2AP,CDC42,GTF2H4,SUPT7L,SSR1,DSTN,ALYREF,METAP1,KMT5B,MIF,RPS27L,EDC3,AKAP8L,TNFRSF14,SMCHD1,MED27,METTL18,RPL17,HNRNPK,GNAI3,HBP1,CBX3,PIK3CA,INTS10,PRMT5,ZMYM2,SMU1,MIDEAS,MATR3,STAT1,STX16,BTF3,HNRNPAB,SFN,COX6B1,CREBBP,RPS26,DDX5,SPECC1L,SMARCD3,PACSIN3,PHB2,NDUFS2,GOSR1,SRSF2,TOM1L2,MRPL12,ZC3H14,USP6NL,WDR82,SIN3A,HSP90AB1,CCT7,SNRPD3,RAB1B,CTNNB1,BTF3L4,DDRGK1,NDUFV2,YWHAG,RAB5C,PTDSS1,ARMC8,MAGOH,DDX1,MGMT,LSM14A,ABCF1,CYP1B1,CBLL1,RAB18,RPS4X,RUVBL1,FOXJ3,NUP37,PTS,PTRH2,PLS3,ALB,RPS12,DNASE1L1,TRIM27,POP7,TUBA1B,JUNB,SCML2,DNAJC8,ZNF687,SMAD2,ARFGAP3,HMCES,ZKSCAN1,PIK3R2,CDK7,DENND2D,SLC35E1,UQCRC1,RABL3,SYNGR2,RARS1,MEST,METTL14,DECR2,PTPN1,ZNF652,SMAD3,RPL12,CITED1,NCBP2,SEMA3C,RPL35A,ATP1B1,SETD5,MOV10,GRSF1,ERCC3,H2AC14,OSBPL8,CLP1,RPL23A,NKRF,TCOF1,PPP1R12A,MRPS18C,PAGR1,B4GALT7,FARSA,NOC4L,RNF121,ACTR2,NDUFS3,LLPH,SEC61B,POLR2F,FAM91A1,ACKR3,PRRC2A,ERH,MED17,TAB1,ACTB,PRDX2,SMARCE1,PRPF31,PIK3R3,SETD7,VMP1,HSP90AA1,EXD2,CSRP1,NOP53,PPP2R3A,CDKN1A,DAAM1,NDE1,ELOVL1,ARMCX3,LARP4B,KRT8,RPL8,DHX15,PPIA,SRSF10,ZNF207,INO80E,BABAM1,DICER1,MED4,PPM1B,BCKDK,HNRNPA2B1,GADD45A,HSPD1,RAD21,TMED7,SEMA4C,S100A10,ASF1A,ZNF592,ZBTB16,PPP2R1A,DLG3,MACO1,CSNK1E,SNRPE,POLR2D,RAB6B,CTNNA2 |
| 3.449e-29 | -65.54 | ESR2 (estrogen receptor 2) | protein interactions | 2100 | 2298 | 877 | 19454 | 5460 |
SNRNP27,TRAM1,MRPL10,CAPN1,HEXIM1,GSTP1,ACACA,RPRD1B,H2BC11,EXOSC4,UGDH,EIF4E,MARS1,RBM22,EXOC5,ANAPC4,CALU,RAP2C,NR0B1,LACRT,TRIM23,MOB4,PSMC5,GTF2H2,RPS3,UBN1,LIG3,SRPK2,BCCIP,SRC,BUB3,PPAT,GABPA,WBP11,ZMYM3,TMEM205,MTCH2,RAP1A,CARD19,TFRC,TMEM165,SNIP1,SLC25A11,TMEM50B,FKBP8,CAPZA1,CDC40,KDM4B,TMEM33,SRPRB,HP,KARS1,RBM17,CDK12,SMAD4,STT3A,EEF1B2,TMPO,RBM42,ARL6IP5,DNAJC1,MIOS,NKAP,CD59,CLDN4,TANK,FDFT1,CTBP1,EP300,SNRPA,HIRA,SAP18,EMC1,RER1,COX11,MLF2,PCCB,EPS8,POLR1B,THOC6,LAMTOR1,H1-10,SF3B4,FAM83B,BST2,PHF12,NFKBIB,PPP5C,ATP5F1B,TRAF2,KLHL12,KDELR1,DNAJB4,CCT8,PPIB,PPFIBP1,DRG1,MAGED2,RMND1,DYNC1I2,SIPA1L1,PRMT2,MX1,CNP,CPSF4,RBFOX2,RPLP0,TM9SF1,OXSR1,ZNF574,MRPS34,LSM2,TMEM126B,H2BC12,ARPC2,PRPF4,NHP2,POLDIP2,SGF29,GTF2I,DGCR8,SMC4,PPP1CC,HYCC2,CDC16,PYCR2,NCKIPSD,TADA1,CASC3,LGALS8,GANAB,RPS20,STUB1,EIF4A3,SH3BP4,VKORC1L1,KLK9,LDHA,YES1,EEF1A1,DDX39A,GNG10,MTA3,TBK1,MRPL11,GEMIN7,SNAP23,PC,DLG1,ZNF787,ARF4,CNOT6L,PAK1IP1,TOM1,MPG,MFN1,ORC5,TMEM199,EMC4,FBXO34,MED21,EXOC2,MPHOSPH10,PWP2,SRPRA,HACD3,ETV6,SRP14,AKAP17A,PRNP,PPP1CB,SUPT3H,WDR77,RTF2,MED23,ATP5PO,ADNP,TMEM256,HADHA,EEIG2,THOC3,RTKN,RBM15B,PYCARD,EXOC8,SP1,SLPI,LMNB1,CLDN3,PIGK,RAN,CHCHD3,GNB1,TMCC1,TNPO3,SNRPB2,RPL35,CYB5R1,RBM38,NUP153,TXNRD1,RBPJ,CPE,BPIFB1,INO80C,ZC3H7A,HSD17B8,MORC2,TRIP4,PLSCR1,MRPS17,SRSF4,HS2ST1,RFC2,TRIM26,RBBP7,EMC8,TRIM37,RAP2B,TRA2A,WDR11,EIF3D,CLPX,C2CD2L,RPL23,CD58,HBA1,PBDC1,CCDC127,MYEF2,PPP2CB,NDUFS8,ODC1,BUD31,SNX2,CDC42,HPS6,SSR1,LSM12,PGK1,DLAT,MAIP1,RBM23,PML,NBN,WDR55,NINJ1,HDAC3,AIF1L,NME4,RPS15,CFL1,GORASP2,SUGP1,EXOSC1,RBM7,ALKBH5,GEMIN8,CHRAC1,PRSS8,SRP54,RBMX2,INTS12,UQCRC2,PSPC1,STAT5A,ATP5PB,SYNGR3,GNAI3,ZNRF1,CBX3,SNRNP48,EDC3,USP3,AKAP8L,SMCHD1,DSTN,ADD1,RAP1B,ALYREF,VTI1B,MIF,RPS27L,TOM1L2,LAP3,ZC3H14,MIA2,DDX39B,SPECC1L,PACSIN3,NDUFS2,GOSR1,SRSF2,FXR2,TRA2B,PHB2,BTF3,RALGAPA2,STX16,SNRPB,CREBBP,SFN,FIS1,MRPS25,S100A11,RRAS2,PRMT5,INTS10,SMU1,DKK3,ZMYM2,PSMB6,STAT1,TMEM59,H1-3,FOXJ3,SMARCB1,PTRH2,CYP1B1,LSM14A,RPS4X,CBLL1,RAB18,PSMA2,EPHA4,YWHAG,CTNNB1,DDRGK1,SRD5A3,RAB5C,ZCCHC10,PTDSS1,MGMT,CDC23,MAGOH,H2BC17,WDR82,NDST3,SIN3A,PRCC,CCT7,RAB1B,SNRPD3,SNRPA1,UQCRC1,SF3A1,TXNL4A,RABL3,SYNGR2,HNRNPH3,RPL26L1,RARS1,DCTN4,GOLGA5,CHMP1A,RTN4,UQCC3,CHMP2B,CDC42EP4,NF2,SMAD2,CDC73,SDF2L1,DNASE1L1,TRIM27,RPS12,POP7,RPP25L,UBE2V1,TMEM126A,VAC14,SERPINA1,LLPH,NDUFS3,ACTR2,CCNY,RAB1A,SFXN1,ELOVL7,B4GALT7,NOC4L,GRSF1,MOV10,LAMTOR2,OSBPL8,CLP1,DECR2,RB1,PTPN1,ZNF652,SMAD3,NCBP2,THOC1,SEMA3C,SUPT4H1,ACTL6A,NDE1,DAAM1,MFAP1,USP39,ARMCX3,LARP4B,PSMA3,ZFP64,EXD2,PXMP2,CSRP1,NOP53,TMED3,SMARCE1,PRPF31,TMED4,HSP90AA1,CNIH4,BAX,VMP1,RHOB,SNRPD2,SEC61B,ACKR3,CLIC4,ERH,PRDX2,MED17,RPF1,TAB1,ACTB,PPP2R1A,ERLIN2,SNRPE,CTNNA2,HSPD1,MAP3K11,HNRNPA2B1,BCKDK,TMED7,GTF3C3,FOXP4,FLOT1,RAD21,ZNF592,SEMA4C,ATG9A,BABAM1,MED4,RPLP2,RPL8,GTF3C4,NTPCR,SUMO1,UBE2M,UTP15,WRAP53,SAMM50,ZNF326,TWNK,PRDX6,APMAP,HCFC2,ZC3H15,KDM1A,MRPL41,TIA1,RPF2,SUB1,GSTK1,ATP1A1,RRP7A,EIF3G,PKNOX1,QSER1,STX10,CREB1,PSMA6,CSTF3,PPP1R10,RALA,ADRM1,ARHGAP12,H2AX,ZMYM4,ANGPT1,PREB,TAB2,TAF2,PSMC3,CHAMP1,IK,RBM34,ARPC3,MAN1A2,PCYOX1L,CEACAM5,TOLLIP,IMP4,NR2F6,CSNK2A1,DNAJB2,ZNF24,SNRNP70,BECN1,NOS1AP,NDUFB4,COQ10B,COX4I1,SURF6,YIPF5,DHRS4,NDUFAF3,PABPC5,NUP62,HSPA8,STK26,AKAP1,LCN1,SLU7,RFC4,XRCC5,RPP14,SSR3,EYA3,STAU1,RPL39,DNAJB6,NSA2,SPCS3,CHTOP,ANAPC2,ZHX3,LORICRIN,EFHD2,PSMD4,PSMD6,KIF2A,PPIL3,MTA2,SEC61G,CAAP1,SEC11A,FKTN,HNRNPDL,POLDIP3,ZNF609,VDAC1,TBC1D5,GSTM3,YWHAB,CORO1C,EED,PNPLA8,HMG20A,EIF2S1,FAM98A,TCP1,LYAR,HACD2,ATG16L1,SAP30BP,FUT8,MYL12B,HSP90B1,MAVS,SQSTM1,MME,SIRT7,PNO1,SLC5A6,AATF,CERS2,CTSD,SEC13,TXNIP,TADA3,ZNHIT3,RTRAF,TRIM24,ACAT1,TECR,TENT2,SEC63,TXN,MAGOHB,PPIF,GGCT,CCDC47,SAP30L,RAD23B,SRP72,DMAP1,CREB3L4,GABPB1,SEPTIN7,ZC3H11A,HSD17B10,EMC2,SLC25A10,MRPL22,MDC1,EIF3E,LSM4,HDAC6,SLC2A1,UBP1,DBT,SLC25A12,G6PD,CAV1,NOP9,NRDE2,ETF1,MTX2,MYL6,NDUFA5,ATP5MK,ZNF668,RFC5,MCM3,CUL3,CFAP20,MYO6,SLC30A7,RMDN3,CPSF1,ZNF22,EIF3K,PARP2,MAD2L1,RPL7L1,DCUN1D3,MARCKSL1,FTHL17,PLD3,AP2S1,STIM1,SLC39A7,UBE3A,AP1M1,RFC3,PCGF3,LAMB2,ETFA,EMC6,PSMD3,STOML2,RSBN1L,SLC35D1,CAMSAP2,KDM2A,TSG101,XPO5,RPLP1,DNM2,PHB1,FAM3A,OCIAD2,RAB11B,LRWD1,NOP58,SPTAN1,AGO1,LEMD3,CYC1,CSNK1G3,WWP1,HBB,LIN7C,NLE1,ITM2B,CLU,WDR3,CNNM4,AKT1,SLC25A1,SMARCA5,CDKN2AIP,CSNK2B,MACROH2A1,CDIPT,SF3B6,FAM210A,IDE,DYRK1A,RSL24D1,CTSB,IRF2BP1,DAPK3,IFI6,SPRR1B,STRBP,IMP3,RPSA,SLC25A24,EXOC3,CDK8,CAPZA2,CLPB,H3C1,PSMA5,TPM3,ELOC,COX5A,LSM3,KPNA1,TAF9,GATAD1,MRPS9,MYL12A,STX6,KCTD3,TMED9,CAND1,SEC62,TOMM22,EFHD1,MTF1,ATP6V1C1,DUSP14,UBL3,NUFIP2,CSNK1A1,TRMT112,NLRP6,TAPBP,MED13L,RPS28,UFL1,EEF1G,KANSL3,PSMD1,SLC30A5,CPSF2,APOBEC3B,ATP5MC3,PDF,RCL1,SERPINH1,CCT2,PNRC1,CIRBP,RPS6KA4,RCE1,MRPL13,VDAC2,DLST,POLR2B,RPL10,ESR2,NCKAP1,APEX1,STAT2,REEP3,DHX38,NDUFA12,RPS23,GNAQ,HGS,PDHA1,FAM168A,GNA11,NAB1,USP30,YWHAH,XPO1,DNTTIP1,QPCTL,NGDN,EXOC1,BAZ1B,CNOT2,AVL9,RAB35,RBM5,ZNF740,ISG20L2,PEX13,SUMO3,SEC22B,SHOC2,WTAP,STOM,SLC12A2,ZCCHC17,ANAPC16,PPIH,INPPL1,SOD1,IDH3A,DAD1,PIAS1,UTP23,PDHB,TAF5L,AP2A1,NRP1,YPEL5,GGCX,PPIG,ASCC1,EIF2AK2,ENO1,CTTNBP2NL,GNAI2,VIRMA,TMOD3,ZBTB17,CD2BP2,EXOSC8,CCT5,POLR2G,SMN1,TMEM50A,HUWE1,CNOT7,ATP5MG,SPATS2L,FOXP1,NME2,PPIC,BOK,KRR1,EIF4E2,MDM2,CDK9,TOMM70,MRPS23,NOTCH2,IRF2BPL,SLC25A3,ANXA7,VAPB,VPS18,EMG1,HSDL1,RGS19,CMAS,CYFIP2,YTHDF1,RPS29,PKP4,SCFD1,LSM14B,MED10,FYTTD1,BRCA1,YWHAZ,SNRPD1,GNG12,GLIPR2,VPS72,MRPL23,LGALS3,FAF2,ARFGAP1,HSDL2,POLR2C,RPS11,SART3,SKA3,BZW2,OPA3,MRPS11,SRSF7,ZYX,SCYL2,MSL2,ATP5F1D,HAX1,CDK5RAP3,SKIC8,WDR12,ZCCHC9,DROSHA,MAP1LC3A,ATP6V1A,PSMB4,MRTO4,NUP35 |
| 4.651e-29 | -65.24 | catalytic complex | cellular component | GO:1902494 | 1708 | 702 | 19108 | 5553 |
PSMA1,GNPTG,CSNK1A1,TAF7,OGDHL,PDHA1,KLHL22,WWP2,ING5,CDK5R1,CLP1,PRMT5,ATP5F1D,MAX,FBXL19,MKLN1,CUL3,APPBP2,SMARCB1,RMND5B,PSMB11,NDUFS3,SKIC8,GTF2H4,DYNLRB2,PPP2R1A,DHX9,GTF2F2,TADA1,POLR1D,ELP3,PRPSAP1,C9orf72,TENT2,PHC1,BUD31,PSMD3,UBE2I,RTRAF,PIK3R1,RBBP7,PCGF2,E2F6,SNRPB2,CTU1,GNAZ,NHP2,PAFAH1B3,KLHL15,KLHL7,SLA2,RAC2,CDK4,DPM2,COX6A2,PRKRA,ZNHIT1,GOLGA7,PSMB5,COX8A,RRM1,GNA11,FAM98A,FBXO32,ASCC1,PPP2R5E,ZFAND2A,BRMS1,GNAO1,CXXC1,CCNH,PELP1,ATP6AP2,CTNNB1,SMARCD3,FBXO7,HNRNPC,WDR5B,CSNK2B,PSMB9,POLR2F,PCCB,FEM1B,LSM2,TOX4,GPR37,POLD2,VPS4A,POLR2G,CDC16,RNF14,PIK3CG,SGF29,UQCR11,ATP5PO,ZER1,RING1,TNFAIP1,NCK1,PTGES3,FBXO8,TMEM199,UBE2D3,SNRPD2,MED27,ATP6V0E1,GNAQ,DCAF8L2,ANAPC13,CSNK2A1,PSMA6,ORMDL1,TBK1,FBXO11,PPIF,MED30,CDC40,SNRPB,COX4I2,TAF2,BECN1,IMMP2L,CACYBP,FBXO25,VPS4B,SPOPL,SNRPN,APOBEC3F,RNF8,DAD1,PRKACB,STK11,NHEJ1,GCLC,KLHL25,RBM15B,PAXX,DGCR8,TXNL1,POLR2L,NDUFB6,BCS1L,WWP1,TCEA1,PIK3R2,POLR3H,ANAPC15,SPTSSA,TSN,SPSB3,ACTL9,ENO2,SMARCE1,SAP30,KLHL3,CDK1,PSMD6,FZR1,PIGK,UQCRQ,RABGGTB,UBE2A,ACTL6B,RNASEH2C,PSMB10,EED,TSEN54,DYNLT3,IDH3B,NAA50,SESN2,KLHL24,ERH,TAF11,CYB5B,CCND3,DKC1,MNAT1,ATG3,PIGY,PPP2R3A,EIF4A3,PSMD10,RAG1,PGGT1B,GNG3,NDUFA1,CDKN2D,RB1CC1,PCMTD1,EPOP,RUVBL1,SAP30L,CDK7,FBXL7,FBXW11,INO80E,RB1,BRMS1L,PIK3CA,EXOSC3,GTF2F1,FBXW4,WTAP,CAB39,STUB1,PABPC1,DCAF11,PRPS1,NDUFS8,GID4,LDHB,INO80C,CUL2,THBD,DMAP1,GNG2,ATP5MK,SEC11A,CDC23,ATP5F1A,UQCRC1,MAD2L2,POLR3B,SNRPA1,UBE3A,HNRNPA1,PSMA2,PCNA,STT3A,DYRK2,PSMD1,ACVR1C,PSMD4,SNRPG,TRMT61A,CRBN,SPCS3,PMPCA,GNG11,POLR2B,COX4I1,RBCK1,GNG10,SETD5,TFIP11,ATP5MG,PAFAH1B1,CKS2,FEM1A,HNRNPAB,GNAI2,COX6B2,DDX1,APOBEC3G,NUDCD3,RPP14,PSEN2,HSD17B10,POP7,PSMB4,KARS1,POLD4,USP14,ILVBL,SPTSSB,SUPT7L,HEXB,NDUFV2,CYC1,PPP1CC,NAA15,BAZ1B,DCAF4,UQCRC2,NAA35,PPP1CB,SOCS3,GNG12,F7,JADE1,ATP5F1E,NAA30,CDKN1B,ATP6V1C1,GPD2,NDUFAB1,PSMB1,EEF1E1,MBD3,SMG5,SYNCRIP,CBLL1,HINT1,DHX38,RNF11,KANSL3,TERC,FCN2,MAGOHB,SNRPD1,PPWD1,PPIL3,PSMC3,DET1,UBE2L3,NCSTN,MPHOSPH6,SF3B6,GNB3,NDUFA2,PRKAG1,GPIHBP1,TOPORS,COX5A,QTRT2,HDAC6,RPN1,NDUFC2,MED21,TRIM21,FBXO3,PPP2R2C,ACVR1B,COX7B,PAFAH1B2,PHKA1,CCNB1,RNF40,PYCARD,POLR1H,CDK12,FAM8A1,CBR4,MSL2,GNG13,MAVS,SUCLG2,MED11,SPCS1,ELP6,ATP5MC1,PSME1,LSM3,CNPPD1,SOCS5,FBXO9,PSME2,TRAF7,SUPT3H,MTA3,IKBKB,TAF5L,NAA16,DTL,NDUFB7,ADRM1,TGFBR2,CAPN1,CDK2AP2,PSMB7,C1D,POLR2I,FNTB,CCND1,COX10,FBXL14,COP1,EXOSC4,DNAL1,COX6B1,WDR77,TBC1D5,KCTD17,ALYREF,DBT,RNF7,TRIM37,DNTTIP1,CREBBP,FBXL3,PRPF31,UBE2V2,ANAPC2,ANAPC4,MCM3,GTF2A2,HNRNPF,ATP6V1D,CHRAC1,RNASEK,UGT1A1,SIN3A,PHKB,GNAI3,STRADB,DNAL4,RARS1,HADHA,FARSA,KDM1A,GNGT2,BCCIP,RRAGB,PIK3R3,CBX5,POLR2D,RCHY1,ENY2,MTA2,BCL7B,ATP6V1G1,TICAM1,NUS1,GANAB,PSMD7,ANKIB1,PDHB,DDX23,LDHA,EXOSC8,PRDM4,HRAS,RBM22,NDUFS2,NDUFA4,MAT2A,GPAA1,PAAF1,HDAC3,DYNC1I2,ENO1,CRADD,VIRMA,BRAP,SNRPD3,PSMC4,DYNC1I1,SF3B1,EP300,HNRNPK,FBXO31,UBE2N,YPEL5,HTRA2,CDK9,SRSF1,PDSS2,THG1L,DCUN1D5,PSMD12,APH1A,GNB1,ZFAND2B,GNB4,CDKN1A,NDUFB4,RRAGA,TSNAX,BCL7C,AGO1,NDUFB5,METTL14,MEAF6,HDAC5,KBTBD6,RAD23B,MORF4L1,GUCY1B1,PPP2CB,SHOC2,GTF2H2,OST4,CLPX,PHF21A,PPP1R12A,GTPBP1,CCNI,ATP6V0B,AZI2,PPP2R5A,TAF10,TUSC3,DPY30,PHF1,SMARCA5,PSMB6,PPP3R2,SPSB1,GSK3A,SPOP,CWC15,ANAPC11,TAF9,GTF2B,RUVBL2,PARD6A,KGD4,DCAF5,SYVN1,PHKG1,VPS72,RPP25L,ATP5PF,ATP6V1E2,LIG3,PIGC,ELOC,CDK8,ATP6V1A,FBXO42,WDR83,POLE3,UBE2V1,ATG101,PPP1R10,PRPF19,FXN,CDC73,TERT,PSMC5,SNRPE,MED17,GNG5,QRSL1,RFC4,SOCS2,BRD9,PCGF6,DROSHA,DCUN1D3,CDC26,POLE4,ING2,PSENEN,NSMCE3,MBL2,VAC14,BRCA1,COX7B2,RANBP10,SS18,ASB1,DIS3L,POLR1B,UQCC3,NDUFB8,HSPB1,ORMDL3,POLR2C,SF3B5,GNA14,DR1,PRIM2,CCNA2,HNRNPA2B1,WRAP53,WDR82,CBX7,CDC20,RNF144B,DCAF4L2,COX6C,CAND1,GTF2H5,ERCC3,EZH2,DDX5,NDUFA12,XRCC5,KLHL9,ATP6V1G2,DCAF16,RTCB,CFDP1,DCTN4,GOLGA7B,DEK,PSMB2,HR,DYNLL1,TRMT6,PSMB3,CCNF,PHF12,MAGOH,CDK5,NDUFB10,CDK6,SOCS4,SIAH1,ATP5MC3,DAPK1,ACTB,GTF2E2,CTNNBIP1,NRBF2,PPP1R3C,ELOVL6,GTF2E1,RPP21,POLA2,EXT1,MAT2B,DCLRE1C,EXOSC1,DCAF12L2,CISH,POP5,DCUN1D1,MED31,GNG7,GID8,HEXA,ATG16L1,DICER1,SKP1,SPCS2,LDHAL6B,KLHL12,PSMA4,RBBP4,POLR3GL,MAEA,CASC3,CAPN2,PPP4C,PSEN1,CCNY,SNRNP40,KCTD10,SF3A1,TMEM183A,PSMA5,PPP3CA,FBXW7,SLU7,CARHSP1,ENC1,SDHB,NDUFS6,ATP5F1B,CAMK2G,TSEN34,SDHC,CKS1B,BCKDK,UBE2S,CCDC65,FBXO44,HCFC2,RMI1,TFPT,NAA11,RMI2,ANAPC16,FEM1C,ACVR1,GTF2A1,RERE,TANK,OS9,HDAC11,IGF1R,CDC5L,CCNQ,PIGA,DISC1,PSMA3,SAP18,PSMD14,NDUFA5,DLST,TADA3,PAGR1,PCGF3,COX7A1,FBXL4,MARS1,EZH1,ATP5PB,TRAF2,UBE2D1,ACTL6A,DLAT,RNF20,CYB5R3,RPP25,UBE2B,HSD17B8,PSMC1,IDH3A,AKAP14,PRKAB1,ESS2,MED10,ARMC8,OTULIN,MIDEAS,UQCRH,POLR3F,ATP5PD |
| 4.917e-29 | -65.18 | protein binding | molecular function | GO:0005515 | 13983 | 4464 | 18094 | 5411 |
TMEM47,MAPK10,CLN8,JKAMP,CUTA,DLK2,DCTPP1,CNTROB,MRPL18,SLC25A10,PRR3,GSTM3,METAP1,TMEM127,TMEM60,CYP2R1,NSMCE3,UBE2V2,SF3B1,TMEM252,DDT,CPNE2,GRID1,FABP4,RDH12,KCTD11,PLAGL1,SLC35A1,FBXO11,DAP,GOLGA5,NAP1L5,SLC35E3,FAM229B,IRF2BPL,RPLP0,SOCS5,DDX42,FOXP1,SYNJ2BP,FGF17,HAND2,SEC22A,IGSF11,PHAX,PIP4P1,TMEM88,ABCF1,FGFBP1,MRPL36,TSPAN15,PHF23,COMMD5,FXR2,H2BC14,ADSS2,ERO1A,KCNS1,MTRES1,PPP2R1A,LPXN,NUP62,PNMA3,PELP1,CLDN22,RNF141,KCNMB2,GNG2,CHRAC1,CST3,RAD23B,FASTKD5,CXCL10,TTLL10,CLDN9,TRIM63,TCP1,BAP1,SLC20A2,SNX5,SOS2,ST3GAL2,COL1A2,NME1,ETFBKMT,IFNA10,TMCC2,TIMP1,PC,RER1,RELL1,EFNB1,GNPTG,CCAR2,ANKMY2,GAD2,GGPS1,MFSD14B,LRRN1,FZD3,SOD1,SMUG1,LILRB1,CLBA1,SHC1,ATG16L1,CD28,RIOX2,LCN9,SLC2A1,ADD2,DSTYK,URM1,ETF1,ATP6V1D,COX14,SMARCB1,EGLN2,SHC3,ASIC2,MYH1,IFNGR1,DLAT,ITGB8,SRSF1,KCNB1,TMOD3,SYP,NCALD,ODAM,PALS2,FGF13,RALYL,TRAPPC10,GPBAR1,RABIF,HSD17B8,DESI2,GABBR1,TSEN54,PSMB5,TRIM22,KHDC4,EIF4EBP3,KCNJ3,NUP107,SEC13,PDHB,CD9,ESD,BTF3L4,PSMA6,ERG28,SUMO1,UQCRC1,RNF122,CYBC1,EMP2,CXCL14,RPL23A,FBXL7,PEDS1,NR1I3,RPS9,ACTR2,HPS6,ITK,SNX22,MACROH2A1,RPL27,GALE,CSKMT,RBP5,VEGFA,MCCD1,DISC1,RDH10,BACE1,PAIP2,NAA30,TMEM237,RAB2A,CRYAB,DEFB1,AIPL1,FAM78A,PPP1R1A,NOG,CEND1,C1QL2,PTGDS,NFKBIB,FERRY3,ICAM3,IFI16,GTF3C3,IGF1,IL13,MTRNR2L3,PDHA1,PDIA2,NDUFC2,SUMO2,TRIB1,BBS5,GPX7,NACC2,GSTCD,FRRS1L,THRAP3,CTSC,HOXC4,PKNOX1,PPIA,ISG20L2,LRRC8D,TOB2,HOXD12,MARCHF3,GFI1,SPATA2L,DUSP9,DERL2,EIF4B,MGAT4B,TAF1D,PSMD14,CRYBA2,THBD,CDC42SE2,NEGR1,PPP1CB,SNX18,ZMYM3,MAP1LC3A,PFKFB2,TUBB4B,MT1A,UAP1,ZDHHC15,FKBP4,TAGLN3,NUP153,CD1A,RGCC,TRIM15,MTRNR2L7,CRELD1,PPM1B,PSORS1C2,TXNRD1,CNIH4,CKB,VPS28,JOSD1,ICAM2,LMBRD1,PRPF18,SLC39A13,C2CD2L,RBM41,CTU1,TNFAIP6,CAPZA2,CTBP1,MYC,MED17,TAC1,YWHAG,CFC1,SERTM1,KPNA2,AP1G2,CPT2,REEP3,OTX2,HSPB8,RPL18,PFDN2,RPN1,CCSER2,CLP1,CTLA4,UCHL3,PSKH1,STX12,CD80,APBB3,GCC1,CKLF,EIF2AK2,EIF4A2,SLC35A2,RAB1B,SPTSSB,GPC1,SRPK2,NEK2,F11R,KLHL9,RAMP3,MAP1LC3B,PHKG1,PHB2,PRDM4,DDRGK1,VPS26C,KXD1,EHD3,KLK5,CXXC1,FAM43A,MAGEC2,S100B,ISG15,CD40,TCF21,TWIST2,SCGB1D1,IL6,SERPINB1,ZFP64,INO80C,VAMP5,NDUFB6,CYP2C8,RASL12,RAB5A,PIGA,TIMM8A,SDHAF2,NCAPG2,PSMD3,SFTPC,DBT,TEX47,TYW3,SPMIP9,EMC6,PAFAH1B1,CYB5B,CDC42EP4,CD63,NAA35,CSK,WDR5B,SLC7A1,PDCD5,BUB3,ECRG4,CAB39,AKT1,RGS10,MRTO4,FKBP1A,RPAP2,IPCEF1,TRAPPC4,UQCRC2,MED27,CDC5L,ATP2B4,SEC22B,RPL26,LRP12,SART3,STUB1,F9,PRKAG1,TMUB1,TCEAL1,ANKRD50,FRZB,KIF1C,LDLR,PPY,EXOSC8,MEF2B,PSME2,CCL24,CATIP,MSRB1,IL34,AKR1A1,BATF,ZNF576,CSNK2A1,SH3BP4,SRSF8,BTG2,HBP1,NRSN2,MOBP,PRR19,TMEM231,NPW,EVA1A,FGF7,OXSR1,BMPR1B,SPC24,SPRY1,CYP1A1,GGCT,MEPCE,FGF22,CMTM7,DNPH1,FUT9,LYPLA1,LBH,COX7B,NR2F6,TCTA,RPL12,PTGES,TXNDC12,LRWD1,GSTA4,MAP3K11,HSPE1,TCEA1,PNPO,NF2,BRAP,CNP,UNC119B,AKT2,AKAP12,PDE8A,MPP1,METTL2A,ENDOD1,NUDT1,FCER1G,EDDM3B,TFIP11,GINS4,CLK1,ARFGEF1,LRRC8B,CSNK2B,LRRC14,PRKCE,FAM149B1,PITPNA,SYNRG,NAA15,PRMT5,TMEM176B,COQ8A,SURF4,SYNE4,NSDHL,SNAP91,RDH11,CEBPG,CNTN1,SIGLEC5,YAE1,PPIC,IMP3,LTA,PRR13,BRCA1,YIPF3,CREB3,TIMM21,GPR37,GTF2F2,RNF41,SLC38A9,SFT2D2,MED29,ZNF862,APOO,BNIP3L,USP15,BMPR1A,CD3G,HEXIM1,HM13,PPFIBP1,ESS2,BCL7B,ASMT,TOMM22,PMAIP1,RFC3,ATP5F1E,TOPORS,KCND2,PHB1,TOMM6,SUSD6,MEST,FHIT,DSTN,CRMP1,CLVS2,IER2,VTA1,LYG2,SPECC1L,RAP2C,ING1,TNFSF10,OSGEP,H2BC17,SPTSSA,PRDX4,RGS2,CEP85,CDSN,CHST13,FAM20B,H2BW1,CNOT6L,HDAC5,OPRK1,SLPI,SNX24,MAVS,VCF1,AGGF1,IL23A,CNPY4,TAPBP,PDZK1IP1,ATP5F1B,MPC1,GH1,SMAD1,DUSP1,SYNDIG1,APOBEC3A,RAD1,NEK7,PAX9,PHETA2,BORCS8,NQO1,CD58,MAP2K6,BCS1L,ADCY2,PHKB,GPX3,JMJD8,SYS1,MSL2,FA2H,ZNF526,RNF26,CHMP2B,RPS13,EGR1,HAS3,PDYN,SLC6A1,TBC1D13,IL1RAP,RAP1B,PSEN2,MTM1,SOX3,SRP72,NELL2,SFTPA1,POR,GON7,GHITM,E2F4,FAM83A,NAA60,TCF19,RNF182,SLC22A6,UTP15,SUFU,VAMP1,TENM3,CD14,COX19,RNASEL,BLCAP,APLNR,AMELX,USP8,SDCBP,ZNF511,RAB27A,GRIA1,TLR1,RBM7,GEMIN8,GRAP2,H1-5,GSTO2,CFAP91,CWF19L1,NAPG,TOX4,CYTH1,PHYKPL,FGFBP2,RPSA,INTS12,TFE3,RPL23,SOBP,TCF23,SIAH1,PSMA2,RPL19,CTTN,OSM,MBLAC2,RPL7,GALNT2,KLK6,MAP4,CBX5,TBC1D5,GABARAPL2,ATP1B3,TRMT1L,PYCARD,SECISBP2L,RNF152,FCGR2B,DRAP1,CIB2,CNTNAP1,ESYT1,TMEM170A,ALKAL1,ZFAND2B,STARD4,THOC1,PPP1R1B,IDE,PLGRKT,MT1M,HSPD1,CSRP1,SNAPIN,CCL11,MRPL53,FBXL4,SUPT5H,SIKE1,PSMD6,SELL,KRT8,CCDC42,WFDC5,ATAT1,DAAM1,TMEM14A,GTF2A2,TMIGD1,SNAPC1,RANBP10,MAP2K1,FHL3,NGRN,ATP1A1,SYBU,TMEM50A,SLC22A17,CLVS1,TOR1B,CFAP90,GJB2,VIPR1,IL10,CDC42,MSANTD4,SYNGR3,TRIM8,NFIL3,TBC1D10C,MMADHC,GPIHBP1,COPS7B,CRYL1,MRPS23,APMAP,FAH,GCFC2,TEX264,PRDX6,RPS3,CCN3,RAP2B,FOXP2,KIF3C,MAX,FBXO9,LHFPL1,SPCS2,TTR,TMEM174,SDF2L1,ADAMTS10,EIF3G,DSN1,COCH,DTD2,ZYX,MARCKSL1,OGN,MMD,OTULIN,CISH,PPP1R26,SLC41A1,SERPINA5,EPHA4,S100A11,SSR2,PSMG3,VTI1B,SPOCK1,MANBAL,UBA52,NCOA5,GTF2E2,DYNLT3,DPP4,LYZ,UGT1A1,C1QL3,KIN,ADPRH,FKBPL,CORO6,KCNJ8,RPS27L,CLDN6,ZNF326,NAA50,CNPY3,FLCN,VPS4A,OLA1,TICAM1,PIWIL2,SYT2,STX18,DEFB129,PDE1B,SNRPB2,CERS6,PARM1,CXCL8,GLE1,SLC12A2,PRKAB1,KLF1,DDAH2,SLC19A2,JUNB,CIPC,MAP3K21,ERVFRD-1,RASL11A,LGI1,BORCS7,ARMC7,VEGFC,ADD1,FBXO3,STK4,CMTM6,UPRT,TBCEL,SAT2,ELF5,PRPF19,ALOX5AP,MOV10,MLF2,PPP1R11,SNX2,ASB1,MRPS17,BCL9,RABL2B,ATP5MC1,OAS1,SERPINA1,PPP1R2,CLSTN3,FGF10,EDEM1,SEC22C,LSM8,TRAPPC13,PSPC1,CKS1B,CD164,MACROD1,LDOC1,FAM83C,DUSP18,DES,B9D2,RAB3A,CCDC172,CSH1,SPHK2,SULT1B1,LY6G5C,CX3CL1,CLDN11,RAB30,WIF1,BTN2A2,PCSK2,DTL,ANGPTL2,CHRNB2,INHA,TNFSF13,PLPP6,NPY1R,PLSCR1,ITM2B,ADRB3,DDX39B,NTF4,TFPT,TNNI1,PTGER4,PDCD10,CD200R1,RTN4,GHR,TRIM62,RPL28,TAF9,CHTOP,MED4,SDHAF4,F2,HDAC11,SH3BGRL,RNF139,CIART,UQCRH,MGAT4A,SNRNP40,MACIR,CDIP1,RPL24,UCKL1,NPTN,NUDT16,FURIN,KDM2A,AGPAT1,AK3,PHYH,RXRG,CHCHD4,TMOD2,FAM162A,EMC2,UBAC2,ADIPOR2,SESN2,RRAGB,CSGALNACT2,TNFSF8,TBC1D4,RNF181,RAB3B,UBAP1,POLR2G,HNRNPA0,ZNF343,TMEM177,PHF21A,MCHR1,ELOVL1,TMEM106C,TRIM26,VPS18,MATN4,TADA3,NEK9,SLC35B4,CETN3,COPS4,ECHDC1,SLC25A27,TSPAN18,VAPB,F7,MITF,CACNB2,DAPK3,STX5,FBP1,BFAR,MGP,HTR1A,MINAR2,ASIC1,SLC35F6,ZNF365,ZBTB39,CRYBB2,DCAF5,ADCY3,DCUN1D3,CNNM4,DHX16,CARTPT,TXNIP,WBP1L,TAF11,ZBTB16,BLVRA,LDLRAD4,NMI,COX4I1,ATP6V1G1,MRPL23,TRAK2,TM4SF20,RFXANK,MED21,ACADSB,DNAJC2,TRIM27,DUSP26,MRFAP1,TRIM32,ACO1,ZBTB2,ADAM21,CCDC25,KCTD12,AP5S1,ICA1,BPGM,TRIR,GABRA2,CEP97,RPS16,APOBEC3B,PFDN5,MRPL12,TCP11L2,CBR4,RFX5,ZHX3,SWAP70,SYK,TRIM44,SUPT7L,YWHAZ,PTS,CFL1,NRM,AIF1,UGDH,SP1,PACSIN3,IP6K1,CD40LG,RASL10B,SLC39A10,GPSM3,RPS7,PDE4B,CLPB,UFSP1,CTSK,FIS1,VMP1,AREL1,POLR2L,CD99L2,TRIM21,GRM1,MATCAP1,CPSF2,WDR37,GTPBP1,LSM4,ACAT1,CABCOCO1,RIGI,CCR7,LAMTOR1,H2BC9,UBL4A,SNIP1,GADD45A,NUP42,VPS26B,GSTT1,LBR,ST6GALNAC3,RMI2,CXCL13,STRBP,DDX5,COMTD1,LPAR6,NUFIP2,PPP1R10,LYPD6,NT5C2,IKZF5,MTMR6,SLC1A3,BTF3,EDC3,TRAF2,CAPG,DHPS,LPAR2,ANP32A,TM4SF18,PSMB3,RPS24,PAK2,ALKBH4,MPG,EPHX1,HADHA,ACACA,IRF8,TMBIM6,LASP1,AASDHPPT,UBL5,EHD1,NOS1AP,CBLL1,NHEJ1,RAB8B,KPNA6,TMEM42,TBC1D16,UBE2I,TACR3,ASPM,SHLD1,VDAC1,KRTAP3-1,IL20RB,IL21,CD247,BMPR2,ROGDI,COX20,FUNDC2,HHIP,SEPHS1,GSTP1,CDR2L,KRT222,RETREG2,CYGB,KLHDC8A,BET1,VXN,SH3BP5L,NLGN2,GOSR2,PHC1,TMX3,SPCS3,HYCC1,BAX,NAPA,AP2S1,SEPTIN7,MME,ARHGAP19,ZKSCAN1,CFTR,IFIT2,NTMT1,FBXW4,RBFOX2,HINT2,FAM81A,RABAC1,DUSP10,FYTTD1,RANBP1,SORD,TERB2,MED23,OSGIN2,VAC14,TMEM95,RDM1,METTL14,TAX1BP3,RTP4,PDCL,TAL2,EYA3,THBS3,B3GNT2,NTAQ1,SLC37A4,TNF,ADRA1A,IQCF5,GTF2E1,ELK1,SULT1A3,BLOC1S5,EIF4E,TBCE,GDI2,CDK5RAP3,BLOC1S2,DAG1,LHFPL4,TRIP4,H2AJ,KCNG3,UBXN10,TRAPPC2L,IFRD2,SYNGR1,BVES,PAFAH1B3,HP1BP3,COX17,EXOC3,CLTRN,PGM1,SOX9,ZCCHC12,ACCS,RHAG,NKAP,CLEC18A,IGBP1,RPS2,MAD2L1BP,GPR17,EHHADH,KCTD10,LY96,CTDSP1,DRAM1,TNFSF12,GPBP1L1,RPA2,NDUFAF4,PTGES3,RNF126,RFC2,POMP,MET,PIK3CA,PRR5L,RPS5,GTF2F1,ENKD1,CXCR6,AATF,CSNK1E,FAM89B,S100A10,FKRP,FGF3,MLLT6,MLC1,OLFM3,TNIK,VAMP7,TCP11L1,LPAR1,ACTN4,RALA,KCNQ5,RPL27A,GPHN,PIP5K1A,TMEM107,ZBTB33,YIPF5,RAP2A,BMERB1,UTP25,TIRAP,UCP2,ACTR3B,MAP1S,PAX6,CCDC90B,ALKBH2,NEFL,TRMT112,MAGOH,WDR12,INSYN2A,RAB3D,NETO1,TSSC4,NUDT3,PSMA4,BPIFA2,CIBAR1,SLC30A5,PRDX1,SMAP2,SERPINH1,MRC1,ERAS,ZNRF1,ORAI2,MGAT5B,SMIM11,DHX15,DRD3,INA,POC1B,ZC3H11A,DLGAP4,PSMB9,ALDH1A3,ALYREF,RPL31,PRKX,CAPN1,LSM3,POLR3GL,EMX2,IFNB1,GADD45B,OSBP,SRSF4,AVPI1,RIT2,COA5,PRCP,LCP2,SIAH2,SEPTIN6,WWP1,ARL6,RPAP3,BPIFB3,TMEM190,CD200,ATP6V1C1,TNFRSF1B,SOX2,XAF1,SESTD1,SYT4,GRIA2,LARP4B,MPST,TOR2A,SAP30L,H3C1,SOCS2,SKP1,VMAC,SRP14,SACM1L,SPSB1,HINFP,TNFAIP8L2,TRA2A,RPS14,PAPOLA,PGR,RP2,SPMIP10,TIMP4,TXNRD3,ASPA,PDSS2,LAMP2,VGLL2,GUK1,ACTL6A,ATL1,RAD21,MFSD5,BRD3,DGCR6L,RBPJ,PCGF2,KATNAL1,MX1,SLC25A23,CCDC181,MMP9,ELAVL2,REG1A,CDC20,GTF2A1,NDUFB7,PLCB2,ABHD17A,PIWIL1,TRIM29,CTDSPL2,FBXO7,PHYHIP,BORCS5,KRTAP12-4,MAD2L2,ABCG2,PDE6D,ARMCX5,PSMD10,DEFB121,TIMM23,TLR6,TIMMDC1,PFDN4,RP9,CYBRD1,RFXAP,UBE2M,STK38L,IGFBP3,YWHAH,ZFP1,OLFM2,CLU,PTPN22,ZCRB1,ARMCX3,RHBG,CFAP161,UCK2,MIR206,TP53INP1,DDX39A,DIRAS1,UBIAD1,CNPPD1,COP1,DNAJC1,TRAM1,REN,LYPLA2,NAIF1,STOML2,DNAJB2,PHOSPHO2,FAU,ATXN10,SPTAN1,S100A6,SMAD4,DIS3L,DCUN1D5,UGP2,GNPDA2,CIRBP,CHST1,ATP1A2,FEM1C,CCR2,CCS,RNF5,ARFGAP1,CREB3L4,DCUN1D1,IL18,ATP5PB,PHKA1,GIPC3,CDH13,DCAF11,RETREG1,ZMYM4,SF3B6,TNFAIP8L3,MAPRE1,ZC3H14,FGD2,SMDT1,RPRD1A,ORC5,ZMAT5,AFAP1L2,B9D1,THOC2,STX17,CRYBA4,ACAA2,SOCS4,RPL37A,ARPC2,ARF4,PSMB2,AK2,RAN,GABPB1,HSD17B10,SLC6A12,MED9,TAS2R5,ANO3,PTPRZ1,RGMA,ABHD6,HACD3,FBXW7,APOBEC3F,SUMO3,SHMT1,RPIA,FNDC11,ALG2,KCTD15,DHRS7B,LY6G6C,LSM14B,CSTA,SEMG2,NFKBIA,SLC51A,CLDN8,SUGP1,TFRC,CREBL2,GHRL,SUV39H1,HACD1,VEZT,EIF5A2,MGME1,NKX3-1,MLLT11,B2M,MBD3,CRTAP,GAPDH,TNFRSF14,TOMM70,CKS2,DIO2,FAF1,RGL2,DHRS1,ERLEC1,MRPS9,STK16,BMP1,PPIH,EFNA3,TMEM199,PPFIA2,CITED1,ABHD14B,RAB19,RING1,GRM2,THAP7,STOML3,SOSTDC1,ZNF821,EED,ARF1,SNAPC5,STT3A,RPL17,SMPD2,CALU,PIP4K2C,CDC7,ANKIB1,LBX1,CFAP97D1,COX7A1,SCNM1,NFKB1,TMSB10,CHMP1B,OAZ1,TMEM11,AZI2,HECW1,LAMTOR3,GNAQ,RPL10A,EPHB6,SLC39A7,TRIM34,KCNF1,ATP5MC3,USP46,APOBEC3G,PTPMT1,PSMB4,KIAA1958,HSH2D,EIF4E2,RNASEK,SPATA6,FATE1,MAT2B,NR1I2,ARF6,SLC7A11,CCL21,SVBP,DNAJC27,SEC61G,LSM14A,SEC23A,PPP5C,GKAP1,NOP53,CPLX3,VAMP2,TAF10,FMO3,ITM2A,PICALM,SCN1B,ADAMTS1,KCTD9,PCP2,HACD2,TEX12,GTF2H5,HCLS1,NAA16,EGFL8,SP4,YES1,TWSG1,PSEN1,VSTM4,BST2,UPF3B,CCDC47,TMEM100,DELE1,PSMA3,BOLA3,STK26,FAM53C,CCAR1,KLRD1,RPLP2,CDR2,VIPAS39,FOXN2,BAHD1,DMAP1,HBE1,SMYD3,GTF2H4,XPO5,RPL7L1,WNT7A,LIN7C,FBXO44,SERPINC1,C1D,FBXO8,BGLAP,NOC4L,AP2M1,SNAP23,EID1,TUBA1B,H2AC13,SDS,ZMYND19,FXYD6,ELMO1,CD2,ATP1A3,FAM169A,ERCC3,ACKR3,UBLCP1,FAM76B,CNOT6,SMNDC1,PDE1A,EGFL7,UGCG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6,TM9SF4,CHCHD6,UTP6,MOSPD1,TPD52,CCR5,THAP1,CAVIN2,FAM221A,CCL8,UBE2D1,LHB,KMT5B,TYMS,CCNQ,SETD3,CCIN,CRHR1,SLC35A5,APOC4,PPP2R5A,HILPDA,FKBP2,FAM98A,SNRPA1,UNC50,NPB,BRD9,OS9,TMEM19,TMEM123,PTPN4,CAMK2N1,SMCHD1,TNKS2,ITGA6,PIGY,TBC1D1,MTX2,HMG20A,LECT2,CALHM3,RNASE1,TMEM220,NUDCD3,JUN,ARL6IP5,LYAR,GEMIN7,HSCB,RPA3,CALR,NLRP2,EPCAM,MAEA,STX6,MMP20,DCTD,PSMD7,CCM2,RNF167,MTA3,NDUFB10,CDKN1B,KDELR1,TPPP2,TSPAN10,SPP1,DOLK,STAC3,CCDC65,SSR1,HSD11B1,KDM1A,SOX14,NAP1L3,REP15,SELENON,PROM1,FTSJ3,DROSHA,XCL1,LEP,RALB,LANCL2,FLRT3,POLD4,GPN2,TMEM182,VPS33A,ATP5PF,CDKN2D,UTP23,RANBP6,DIRAS2,CDCA7L,GSTO1,RNF128,AANAT,CCDC106,YPEL5,CERS2,SEMA3C,EMG1,APEH,WDR11,SUB1,FZD4,BRMS1,SPCS1,MMAA,VPS54,DLG4,CCL27,G2E3,PNO1,TMEM50B,TXNL4A,TLE1,HSD17B1,GNPNAT1,RETREG3,GNA14,MINAR1,ITGAV,IKZF2,SSBP4,ATXN1L,MAK16,SEC61A1,TMEM115,RASD1,ANAPC4,ADM2,NDUFA5,LIG3,LEMD3,RBCK1,ARHGEF6,HUWE1,SMC4,SNRPD1,UTS2,TNFAIP8L1,RERG,HTRA2,RSAD2,H2AB1,RGS1,TAFA1,RFLNA,TIMM13,TRIM3,CUL2,SFXN2,CREBBP,LCMT1,OPRL1,AMIGO1,TMEM97,CLIP3,ASF1A,KLF10,ZNF207,DET1,TAB2,CRHBP,FAAP100,IRF2BP1,FGFR1OP2,ILVBL,DPAGT1,SLC11A2,HFE,WDR20,BACH1,SKA3,ADO,ATP5PO,NDUFAF3,CSTB,SLC22A12,GPR78,SMG8,PRPSAP1,MECP2,RPL3,TAF5L,LRRC4B,ELOVL7,TEF,DNAL4,MYL12B,NUDT9,PRDX3,FAM136A,SMAD9,P2RY4,ACOX1,MS4A7,RMDN3,SCG3,LRP10,FGL2,PEX5L,STAR,CYRIB,PCCB,WDR6,CMKLR2,FBLN5,FBXL3,TMEM219,MTMR2,TRMT10B,MIA2,RPS26,SPG21,SHISA2,S100A8,KLF4,FAM110B,SLC25A14,RPS23,NYAP2,SMAD2,ARL5B,CAND1,GINS3,ANAPC16,ZNHIT6,KLF3,COX6C,RAB39B,NCBP2,CNN3,GOLGA7B,ATPAF2,SUPT3H,AIF1L,RBBP8,AGR2,ELOVL3,FNDC8,IRF7,CXCL9,CSE1L,GNAO1,UBE2H,SNAP29,ZNF593,NOSIP,IL22,TPGS2,GLIPR2,ST13,IRAK1BP1,CA2,CTNNBIP1,STAT1,KCTD17,PLEKHO1,OTUD7B,TRAPPC14,SEC61B,MYOZ3,TMEM254,TMUB2,ICOS,POLR2D,HSP90AA1,H2BC1,PPTC7,SMIM19,PGAM1,DYNLL1,PRKRA,RPE,PFDN6,RIT1,CTDSP2,MAP3K12,PEX26,IFNAR1,NXPE3,HCRT,MED22,STK11,TRIM37,PEBP4,CD274,MRPL9,SNCB,THTPA,NUS1,MRPL51,ATP8A1,CHAMP1,EMC8,C1QL1,CDK12,SST,ABHD4,CIAO1,ATP1B1,PLAAT3,STRADB,PSMC5,ZBTB25,DDR1,DNAJC10,GNG3,LUM,FRMD8,IRGQ,RAB37,PAIP1,FAM83B,H2BC12,P3H1,CPEB1,TERC,HSPA13,NINJ1,LDHB,PPP3R2,NAB2,CYSTM1,EEF1G,HELT,SNRPG,MAP3K3,SAMM50,IRAK4,DUOXA2,LGR4,CCNF,ADGRG1,FITM2,KRR1,AQP4,PTP4A3,CCHCR1,ZC4H2,CDK2AP2,CYFIP2,CHRDL1,SETD7,CHI3L1,KARS1,OSR2,ACTL9,CDK5,ARFIP1,LY6H,UBE2K,PLN,SDHC,MYBL2,TOM1,CHID1,NRGN,AP1M1,DEFB114,STX16,TTC1,TYW5,SPTBN1,ZBTB5,H2BC11,TOLLIP,IVNS1ABP,ANAPC2,BTBD10,MRPS16,TMEM170B,USP2,GCA,NCR3,DNAJC22,STYK1,COMMD8,SCN3B,H2AC25,LRRC8A,TMEM185A,FAM219B,CASC3,RAB32,HNRNPL,SKA1,IFTAP,CCR4,WRAP53,TPD52L1,MAGOHB,S1PR4,RARRES2,ATG7,IRF9,MATR3,PPIL3,DUSP22,ATP6V1A,CDK7,ISCA2,STAU1,TNFAIP1,LMNA,IL4,RPRM,EXOSC1,BABAM1,IFNK,ACOT8,TESK2,TDRD7,DNM2,DNLZ,TRIM11,RNF8,SLC8A1,HGS,UBE2F,MIR31,SATB1,SEC14L5,MRPL57,PACRG,PLCXD3,CCDC134,OGG1,ATP5F1D,VLDLR,PYGB,TWNK,SCYL2,ARPP19,POLR1H,UBTD1,GPAA1,GFUS,RANGRF,CHRM5,PIAS1,LEPROTL1,CAMK2G,WTAP,HYAL2,SLC35F1,CDKN2C,SLC35E1,CCNH,FCF1,VSIR,TPPP3,TNFSF15,LIN7B,STARD13,OXNAD1,POLD2,CHDH,FASLG,HDAC3,SLC5A6,CBL,NDUFAF2,UHMK1,PRR30,PIK3R3,TMEM101,SNRPB,CHCHD2,HSD17B11,CD248,CYP4F22,PNMA5,MNAT1,KCNIP2,RAB28,PTN,EIF4EBP2,LRRC73,ANXA7,RBBP9,DCLRE1C,UFL1,FAM156A,SH2D1A,TUBG1,DNAJC19,ZNHIT3,DLG3,CNOT2,NDUFA4,TSHR,DNAJB4,RHOJ,LDHAL6B,TNFSF18,CXCR3,SEC14L1,CENPW,PSMC4,MFSD6,RPL22,APOBEC3H,MTCH2,GSK3A,SRI,PSMA5,SLC43A2,AVPR1B,HNRNPC,ATF1,AAMP,ARHGAP5,NCDN,TMEM176A,HECTD3,IFT25,PHF12,TRIM23,SDC2,RAB33B,TF,GNB3,GLRA1,PIGK,NBN,AOX1,STK3,TSPAN5,CTXN3,HRAS,LNX2,CAV2,SSNA1,USP5,GORASP2,KLHL3,ZBED1,YTHDF1,RABGGTB,NAB1,PRMT6,HAUS2,LRRTM2,MCM4,PLS3,CCL20,EIF1B,GPHA2,AGA,RPL29,VPS26A,IFT57,NUF2,RGS6,OIP5,CGAS,TENT5D,ERH,PPFIA3,NEO1,L1CAM,TM4SF1,DNTTIP1,TRAPPC6B,DHRS4,ZBED4,CRTC2,LRATD1,ITGA2,PEG10,IL1B,LCN15,EXOC5,TRIM54,CDPF1,RPGRIP1L,IFNA13,CSRNP1,KIT,GGH,RABL3,PPIF,IRF6,ANP32B,OR7D4,NDC80,GABRG2,HAX1,PPP1R16A,TTC8,SRP54,CXCL11,KCNH1,MED10,RNF34,SLC6A3,AIFM1,EGR2,STAT6,ENHO,CAV1,CBFB,ZDHHC16,PRPF4,HBA1,MYG1,CXXC5,LXN,RPL26L1,RNF187,RTF2,CCL4L1,HIGD1C,VCPKMT,TTC23,SRSF2,CCDC85B,DKC1,STPG4,RAB11A,POLDIP3,LDHA,ADORA1,MYD88,SLC48A1,CCT2,EFNA5,CPLX1,AKR7A2,ZMAT2,FBXL19,MAB21L1,HP,WDR44,DDX46,RERE,XPO1,DHRS7,UFM1,MT3,FEM1A,CHN2,SNX3,POLE3,CHCHD1,EIF2B2,AQP3,AKAP14,DNAJC5,ARL6IP6,ARMC8,ZBTB26,ENY2,CWC15,TNPO3,YTHDF2,EPS8,NLRP9,AGER,PPP2R3A,CFAP20,SRSF7,TSPO2,MRPL20,ZNF596,TMEM59,RPL6,RHOBTB3,TP53INP2,GNG10,KIAA0408,UBE3A,PLAA,IL17F,MEF2A,BAG3,MBL2,SLC25A42,CDIPT,MLF1,GSTM2,SAV1,EXOSC3,C1QTNF1,MED30,CAMK1,TOM1L1,CCL3,ADIPOR1,SPOP,MAF1,TNFRSF9,SSMEM1,COMT,SENP8,TAF7,TMSB4X,UBE2B,AZGP1,CX3CR1,ZNF581,GSKIP,FIBIN,EMILIN3,MTDH,COX8A,ZNF436,SCHIP1,MVD,UPK1A,DCK,ACOT13,NOTCH2,GTF2B,NREP,MADCAM1,DNASE1L1,HR,PSMD4,FOXP3,EEF1B2,FCN2,GNG13,NOP58,KDSR,TP53,NEDD8,SNRPD2,TSC22D3,TBC1D24,KLK3,GCLC,LDB1,UBE2E2,RWDD4,VDAC2,SLC16A1,RUSF1,GPNMB,DLST,PDCD1LG2,DGCR8,PLEKHF2,CHRM1,NPC2,RELL2,FZD6,MORF4L1,SCG2,TLR9,TNKS,CHRM3,CD1D,MICB,COIL,FEN1,MIEF1,FBXO42,ORAI3,FBXO25,NPC1L1,GLRX2,HPGDS,ARRDC3,IGF1R,CDKN3,RND3,DENND2D,LEPR,IFIH1,PTPN11,PTHLH,GRPEL2,MAPRE2,NEUROD6,EXOC8,LILRB4,SQSTM1,EXT1,TMEM45B,MID1IP1,LSM2,SLC25A11,PRRG1,TMEM38B,NRP1,TECR,RPL4,NTRK2,TRAPPC3,JCHAIN,PRNP,GID8,G3BP1,ZNF664,MKKS,CDKN2AIP,CAPZA1,UNC45A,ABCE1,LMO4,ECD,FDFT1,LMO3,TMEM41A,IKBKB,SLC35E4,EP300,KLHL12,ADNP,SERTAD2,SAP18,NPBWR1,ISYNA1,NAA11,FAM222B,ATP6V1E2,ARG2,NRBF2,CD38,TSG101,THAP6,LANCL1,SUCLG2,CYB5A,HNRNPA2B1,TTC33,CD151,ANKRD49,CTNNA2,GPX4,OLR1,PRSS23,TPST1,GLRB,LGALS8,SPIN3,ILF2,FOLR1,PAIP2B,TUSC2,SLC1A2,FHIP1B,EIF4H,VPS16,TREML1,RCL1,ATP5IF1,MACROH2A2,BIRC5,SPINK9,PID1,ISX,SEMA4C,MRPL11,TOR1AIP2,LAPTM4A,NMRK1,SNX17,MAT2A,CDK8,POLA2,ZSCAN5A,SMURF1,ENPP4,CYB5R1,MACO1,MAFG,FANCG,TTC4,WASF3,ZBTB18,GNPDA1,TMEM70,TRMO,CLDN4,SHOC2,CCL28,SMG5,H2AZ1,BECN1,ATG4A,JAKMIP1,H2AC6,TFEB,TOM1L2,LYRM2,OARD1,TM4SF19,KLHL26,RAB31,DYRK2,KTI12,SIX5,LDB2,MYL12A,TGFB2,SNX11,RILPL2,SMU1,FOXA3,XPOT,SF3A1,BAZ1B,MGAT1,EMC1,OPHN1,SPINK13,ELOF1,FBXO34,GRPEL1,CCDC69,NHERF1,TTC32,PDE2A,VRK1,FOS,HSPA14,HEXA,SIN3A,AHCYL1,CARS1,TLR5,PKIA,DYRK1A,GPRASP2,OGDHL,CYTH4,RSPH1,FGF23,ZHX1,RWDD1,TMEM45A,GNG7,PPM1D,NLRP3,GTF2H2,SMN1,CD83,EZH2,TMEM167B,SPEF1,ODC1,CD81,NIBAN2,CLRN2,ZNF177,COX11,PIM2,DUSP14,HNF1B,CCSAP,PAFAH1B2,SCFD1,EMC4,PMPCA,KCNA3,AP1AR,KLHL15,PIK3R2,EAF2,FBP2,CLRN1,TSPAN7,FMO1,ATP6V0E1,ABHD5,ZBTB6,ZNF174,SLC25A5,CDH8,MCOLN1,PLAC9,TMEM208,F10,RPL9,ISOC1,PLP1,PGK1,GLYAT,CCL23,TVP23B,RPP21,CPSF1,KIF3B,MAGED2,ACTR1B,PPT1,ARMT1,TCAF2,CLDN14,MAP3K14,EMC9,GTPBP8,DYNC1I1,SENP5,ITGB5,IL2RB,LMO2,ELOVL4,CCL18,TERT,TRAF7,PRM1,MDM2,RPS27A,APOBEC3C,FBXO22,INMT,PPIG,CCDC22,HCST,CINP,SLMAP,TMEM205,PXMP2,PTRH2,GAS2,DOK6,HOMER1,CAMSAP2,SERPINB6,ATP5MG,CBX7,ACTA2,PSMC3,LSM6,CHORDC1,LUC7L3,NPY2R,USE1,XBP1,RAG1,KLHL22,SEMA5A,ORMDL1,GLTP,USP13,MAGEB10,NRDE2,MAPKAPK5,TNNT2,HBM,WNT2,IAH1,H2AZ2,GNB1,FGF1,RUVBL1,PLP2,MX2,MAPK4,CDK9,NOL12,PAK5,PPIB,COMMD2,TMEM229B,DHX38,GLUL,CSTF2T,TLNRD1,C9orf72,HS3ST5,SOST,RHOG,TRIM6,LITAF,ASB8,POLR2B,SSR3,YIPF4,GAS8,HSPB2,NHP2,H2AC4,TNFAIP8,PNMA2,TGFBR2,TMEM266,GPAM,CBLN1,H2AX,IFI27,CLDN3,ZBTB17,PPP3CA,FAM200A,OTOS,HCFC2,IL3,RPP25,KIF2A,REEP4,C1GALT1C1,NOVA1,TBC1D19,LRRC4,IQSEC1,FAM91A1,CXCR1,WDR19,HPCA,WDR77,ARMCX1,CNKSR3,PSMC1,PARD6A,MZT2B,POP5,MNS1,SGTA,USP39,BRINP1,COX5A,MSX2,SNRNP70,TMX2,ASB7,HSBP1,LRP6,FNTB,ZNF513,SLITRK5,MEF2C,SPDYE4,ENC1,KRIT1,SLC19A3,EIF4A3,MSRB3,PMP2,ASB3,PNP,IDH1,ARGLU1,IFI6,VPS4B,KRAS,ADRM1,LRRC61,DCAF16,MEAF6,SEC11A,FKBP14,HMGCS1,TMPO,PHF13,SPRYD4,SIRT7,RPS20,METTL22,PPP1R27,COPS2,CAMLG,PSMD12,ILDR1,ZFAND6,PEA15,WBP2,EIF2S2,WNT10B,HMBS,CISD1,TMEM106B,RNF11,ZNF263,IRF2,IL12B,CDC123,TRMT11,PBLD,SPRED2,DOHH,TRA2B,ATG9A,NXT1,OTUD6B,SLC38A2,USP16,MSN,LORICRIN,GIMAP2,SNAP25,GNA11,NUDT5,AKR1B1,NECTIN2,KLF12,QTRT2,POLR1D,PELO,PROS1,SMIM12,INSIG2,APPBP2,ROPN1B,SV2B,RNF144B,KCTD16,RTRAF,NUPR1,DDIT4,ZNF501,VWF,CAP2,PABPC5,IL15,KCNAB1,RNF103,CENPL,ATG3,RPS12,MT2A,VSTM2A,CRYGD,NUP35,ESAM,C1QC,PDLIM4,LCA5,FRS3,FAM3C,AKT3,TMEM108,IRF4,OAT,TRIM10,RPF2,CHMP1A,TSNAX,NDP,CYC1,AGK,IER3,SPATA2,RBM3,EMX1,IFNG,RACGAP1,NFYA,CAV3,ETV6,CXCL12,POLL,PYROXD2,CIB3,TSPO,ZNF740,NECAP1,MRPS18B,EIF1AD,RNF7,HEBP2,CACNB3,CYTH2,SLC66A2,ABITRAM,SFXN1,TLR2,LLPH,VSTM2L |
| 7.077e-29 | -64.82 | SPRTN (SprT-like N-terminal domain) | protein interactions | 83932 | 586 | 290 | 19454 | 5460 |
EEF1A1,LBR,DDX39A,CCDC47,CCT5,ILF2,PPP4C,DHRS7B,NDUFS3,ACTR2,EMC2,PC,EHD4,RAB1A,SLC25A10,SFXN1,RPS13,ARF4,MSH6,HUWE1,FARSA,VRK1,GMPPA,DNAJC7,NME2,HSD17B11,HACD3,AIFM1,RPL12,ACTA2,EIF4E2,DBT,SLC25A12,CNP,RPS14,RBFOX2,PSMC4,UBA52,RARS1,TIMM23,CDK1,CHMP1A,HSP90B1,H2BC12,CDC42EP4,PDHB,RPL4,BRAP,ATP5F1A,TUFM,GMPS,XPOT,SDF2L1,TMEM74,RPS12,SFXN2,RPS20,ENO1,TECR,UBB,RPL22,RAB14,TXN,PPP2R1A,GFPT1,FAF2,RPS11,RPN1,PCNA,RPS24,SLC25A5,MAP3K11,HSPD1,MEF2C,HNRNPA2B1,MCM6,GSTT1,RFC2,RFC3,ETFA,BCL7C,RAP2B,PSMD3,PRDX1,STOML2,VCPIP1,HAX1,VPS4A,AHSA1,RPL23,RHOG,HBA1,RPLP2,ATP6V1A,DNM2,RPL9,RPL8,PHB1,ERLIN1,STK3,INA,NOP58,AGK,TIMM29,TOR1AIP2,MYL6,SLC25A3,HADHA,ATP2C1,RNF11,PSMC1,CDSN,NSFL1C,RFC5,TOMM40,SAMHD1,MCM3,MCM4,CDC123,POLD4,HSP90AA1,LMNB1,RMDN3,RPL37A,RPS9,RAN,PELO,MAD2L1,CHCHD3,CLIC4,TAF11,EIF4A2,PRDX2,TUBB,PSMC3,SLC25A24,TFRC,ACADSB,TMEM165,ABCE1,SLC16A1,RAB13,DHX9,SLC25A11,RPL17,FKBP8,H2BC14,PSMA5,AKAP12,SRPRB,HNRNPK,KPNA2,TMEM33,COMMD5,GPRASP2,GAPDH,DNAJB2,RPS2,KPNA1,AKAP8L,RPL10A,TUBG1,RPL24,SYNCRIP,SSBP1,COQ8A,STT3A,NDUFB4,COMT,UBE2G2,MYL12A,TMPO,FZR1,RPS16,CAND1,RPS27L,NTPCR,ACACA,HBB,ZNF326,IDH2,SSR1,SAMM50,LSM12,HNRNPH2,RAB9A,RPL27,MAIP1,GRAMD2B,POLD2,CLU,HSPA5,MARS1,NAPG,CFL1,RPS17,H2BC9,RAB2A,SLC25A1,MAT2A,NUDT1,RPL7A,OAT,ATP1A1,CALU,RAP2C,SPOP,CISD1,PSMC5,SEC61A1,RPS3,UQCRC2,CDIPT,SF3B6,ROCK1,SUCLG2,RPL10L,GMDS,ISG15,EEF2,ETFB,RPL18,RPS23,TUBB4B,PDHA1,UCK2,RUVBL2,BCL7B,CCT8,RPL28,RPS4X,RAB18,HNRNPDL,HNRNPF,ROCK2,RUVBL1,VDAC1,CNOT8,XPO1,BTF3L4,RAB5C,HSPB1,MAGED2,FAHD1,SRSF1,CCT7,HSP90AB1,RPS10,TTC9C,ECHDC1,TCP1,YIPF5,RPL27A,TOMM22,PSMB3,UBAC2,PPT1,HSPA8,DDX5,RFC4,FXR2,HNRNPA0,NDUFS2,STAU1,SSR3,EEF1G,PCCB,RALGAPA2,BAG3,MLF2,UFD1,LDHB,HNRNPC,PSMA4,OSGEP,RPS26,H1-1,DNAJB6,CCT2,H1-10,PSMD14,GTF2F1,VDAC2,PSMB6,RPL10,DES,ATP5F1B,PSMD4,MATR3,HDDC2 |
| 1.593e-28 | -64.01 | gag (Pr55(Gag)) | protein interactions | 155030 | 969 | 429 | 19454 | 5460 |
CREB3,IL2RB,ATP5F1A,KPNA6,NONO,IVNS1ABP,EIF4A3,PTEN,UBE2I,LDHA,IFNA10,EEF1E1,CCL3,CNP,CDK1,TOX4,CCL19,RPLP0,MTDH,SQSTM1,EIF5B,RPL4,NUCKS1,FABP4,NFKB1,CD36,SNAP91,APOBEC3F,CD9,PTGER4,AIFM1,SRP14,HACD3,ARF6,PRNP,TOP1,CAV1,MRPL11,PPIF,MAP1LC3B,EEF1A1,ILF2,SRP72,STX8,DLG1,SEMG2,CD80,CCL2,THRAP3,TF,ARF4,OLA1,RNF20,IL6,EIF3E,TXNRD2,CUL2,SAMHD1,RBM15B,FAS,SP1,ARF1,CPSF1,APOBEC3G,RAN,RPL37A,AP2M1,RPL35,DYNLL1,RPL19,TNPO3,H1-5,ETF1,APOBEC3C,PPARG,ATP5PO,MYL6,CXCR4,UPF3B,IL1A,IL1B,GPC1,ATG7,RAP2B,EIF3D,TRA2A,DDX23,LYZ,RSBN1L,BCL2L1,THOC2,DNM2,PHB1,PPP2CB,TSG101,IL10,PTGDS,THY1,CYP27B1,TRIM15,RPL7,SPTAN1,CSF2,NPC2,CETN2,NUP153,AP2S1,AKT2,PPAN,JAK1,G3BP1,AP1M1,SRSF4,AKT3,PTGER2,ATP1A1,RPS3,CREB1,CH25H,PSMC5,SGTA,IL2RA,PRKCE,PPP1R10,ROCK1,SPTBN1,SUMO1,NEK2,VPS4B,SDCBP,CD46,RSAD2,PRL,PRKCA,ACACA,THUMPD1,BANF1,HNRNPH2,TLR2,RAB9A,PRDX6,EIF4E,MARS1,CCL8,HSPA5,KARS1,RBM17,CCL5,COPS5,CSNK2A1,TUBG1,BECN1,CD247,RPS2,CXCR1,IFNA2,GTF2B,ITK,SYNCRIP,CD4,RPS16,ST3GAL5,EPHB6,CD28,TMPO,TLR6,CDC5L,RAP1A,CCL20,CD38,TFRC,TAB2,SLC25A11,RPL3,ABCE1,RAB27A,DYNC1I1,TOLLIP,KPNA2,SRPRB,IL12B,IL12A,ICAM1,DNAJB6,NFKBIA,SF3B4,RAB9B,BST2,TOM1L1,RPL27A,CD59,PAK2,SDC2,IL4,FOS,XRCC5,HSPA8,RAP2A,TRIM22,HNRNPA0,STAU1,SAP18,MT2A,CST3,PPIB,TRIM34,DRG1,SDC4,SRSF1,EED,EIF2S1,TCP1,DYNC1I2,VAMP7,ISG15,UCK2,RPL18,PABPC1,CD83,TOP2B,CCT8,RUVBL2,TRIM11,H1-6,RPL28,IFNG,HSPA14,RPL26,AP2A1,IL2,ENO1,EIF2AK2,TUBA1B,CTTN,MSN,UBB,JUNB,PCK2,UBA52,XCL1,GABARAPL2,FBP2,RARS1,HNRNPH3,PPM1G,IDH3A,PRKCB,PDHB,CHMP2B,VPS28,MOV10,KRR1,ACTA2,CGAS,FBP1,TRIM6,TRIM62,UBE2V1,APOBEC3H,ALPL,SERPINA1,PPP1R12A,TCOF1,NKRF,SFXN1,PTGES,IFNA13,RNF115,SMN1,RAB11A,PSKH1,HSP90AA1,RPS5,CD86,RPS9,EIF4A2,TUBB,LGALS3,ACTB,CD40LG,PRRC2A,INPP5E,RRAGA,VPS18,TRIM5,PPP2R3A,PPP2R2C,SRI,STX7,CCND3,CCR7,HMGA1,MAP1S,PPP2R5A,HNRNPA1,PDCD1,DROSHA,HNRNPD,VPS4A,PDAP1,DICER1,RPL8,RPL9,MAP1LC3A,CETN3,INA,PRKCQ,PPIA,SRSF10,DHX15,JUN,RPL29,PPP2R1A,RPN1,CHMP4C,IL7,PRKAG1,HSPD1,SLC25A5,HNRNPA2B1,SRSF7,TNF,FLOT1,AKT1,RPL7A,CFL1,PRKACB,DNAJC5,IL15,IGF2BP1,OAT,AP3S2,REN,CDIPT,SEC61A1,CSNK2B,PPP2R5E,CTSB,STAT5A,CD2AP,CXCL8,AGO1,IRF3,LSM12,CXCL12,CD81,GAPDH,ELOC,BGLAP,SHC1,RPL24,NOL12,KPNA1,MAP4,IL21,UBE2N,ALYREF,RAP1B,VTI1B,CD2,TLR1,TP53,KIF1C,AGER,CCR5,PSME1,GPX2,DHX9,CHMP1B,TGFBR2,HNRNPK,PSMB10,RPL17,MYC,CNRIP1,APOBEC3B,HNRNPAB,PRMT6,LDHB,HNRNPC,CCT2,SERPINH1,TNFRSF9,CD3G,MATR3,STAT1,RPL10,SYK,GPC4,EIF4B,NUFIP2,DDX39B,CD40,SF3B1,DDX5,TRA2B,EEF1G,PHB2,IFI16,LAMP2,RPL6,RAB5C,PTDSS1,XPO1,IFNB1,DDX1,PSME2,CD63,FEZ1,ACHE,HSP90AB1,CHMP2A,TRMT1L,ETFB,H1-3,TUBA1A,EEF2,PLS3,TUBB4B,SMARCB1,HGS,TRIM21,CDK5,DCP2,HNRNPF,ROCK2,RPS4X,MX2,CXCL10 |
| 1.812e-28 | -63.88 | RNAi effector complex | cellular component | GO:0031332 | 407 | 224 | 19108 | 5553 |
MIR1227,MIR944,MIR607,MIR155HG,MIR10B,MIR942,MIR573,EIF4E,MIR600,MIR196B,MIR24-1,MIR195,MIR187,MIR9-1,MIR215,MIR497,MIR155,MIR338,MIR361,MIR130A,MIR874,MIR940,MIR302B,MIR223,MIRLET7I,MIR339,MIR9-2,MIR214,DHX9,MIR1296,MIR198,MIR489,MIR222,MIR770,MIR221,MIR17,MIR135B,MIR216A,MIR1251,MIR577,MIR101-2,MIR15A,MIR495,MIR331,MIR367,MIR7-1,MIR191,MIR377,MIR425,MIR424,MIR197,MIR572,MIR183,MIR211,MIR551A,MIR192,MIR675,MIR625,MIR152,MIR30B,MIR938,MIR370,MIR100,MIR106B,MIR656,MIR200A,MIR592,PRKRA,MIR218-1,MIR98,MIRLET7C,MIR491,MIR657,MIR873,MIR671,MIR632,MIR106A,MIR29C,MIR320A,MIR505,MIR184,MIR136,MIR144,MIR205,MIR23B,MIR99A,MIRLET7B,MIR1180,MIR636,MIR145,MIR580,MIR556,MIR448,MIR631,MIR32,MIR503,MIR146A,MIR711,MIR761,MIR1249,MIR653,MIR25,MIR204,MIR604,MIR939,MIR504,MIR609,MIR346,MIR137,MIR624,MIR141,MIR936,MIR454,DICER1,MIR148B,MIR640,MIR16-2,MIR488,MIR593,MIR9-3,MIR542,MIR628,MIR30D,MIR148A,MIR324,MIR147A,MIR21,MIR552,MIR190A,MIR149,MIR30A,MIR105-1,AGO1,MIR147B,MIR551B,MIR1-1,MIR16-1,MIR423,MIR1-2,MIR296,MIR345,MIR140,MIR876,MIR618,MIR934,MIR598,MIR569,MIR375,MIR216B,MIR125A,MIR877,MIR20A,MIR500A,MIR101-1,MIR920,MIR605,MIR7-3,MIR185,MIR153-2,MIR23A,MIR206,MIR218-2,MIR105-2,MIR922,MIR153-1,MIR212,MIR7-2,MIR553,MIR335,MIR107,MIR601,MIR26B,XPO5,MIR490,MIR96,MIR626,MIR342,MIR132,MIR611,MIR139,MIR578,MIR502,MIR612,MIR29A,MIR129-1,MIR200C,MIR661,MIR133B,MIR586,MIR484,MIR190B,MIR330,MIR150,MIR615,MIR210,MIR764,MIR99B,MIR10A,MIR126,MIR589,MIR181C,MIR33B,MIR194-1,MIR143,MIR887,MIR558,MIRLET7G,MIR31,MIR450B,MIR581,MIR648,MIR24-2,MIR129-2,MIR194-2,MIR643,MIR455,MIR186,MIR30E,DCP2,MIR452,MIR142,MIR383,MIR590,MIRLET7D |
| 1.812e-28 | -63.88 | RISC complex | cellular component | GO:0016442 | 407 | 224 | 19108 | 5553 |
MIR346,MIR137,MIR624,MIR504,MIR609,MIR939,MIR604,MIR204,MIR25,MIR653,MIR1249,MIR146A,MIR761,MIR711,MIR503,MIR628,MIR542,MIR30D,MIR148A,MIR9-3,MIR593,MIR488,MIR16-2,MIR640,MIR148B,DICER1,MIR454,MIR936,MIR141,MIR873,MIR491,MIR657,MIR98,MIRLET7C,PRKRA,MIR218-1,MIR592,MIR656,MIR200A,MIR106B,MIR100,MIR938,MIR370,MIR631,MIR32,MIR556,MIR448,MIR145,MIR580,MIR636,MIR1180,MIRLET7B,MIR99A,MIR23B,MIR205,MIR136,MIR144,MIR505,MIR184,MIR632,MIR671,MIR106A,MIR29C,MIR320A,MIR101-2,MIR15A,MIR1251,MIR577,MIR216A,MIR135B,MIR17,MIR221,MIR770,MIR489,MIR222,MIR198,MIR1296,DHX9,MIR625,MIR675,MIR30B,MIR152,MIR551A,MIR192,MIR211,MIR183,MIR572,MIR197,MIR424,MIR377,MIR425,MIR191,MIR7-1,MIR367,MIR495,MIR331,MIR24-1,MIR195,MIR196B,MIR600,EIF4E,MIR10B,MIR573,MIR942,MIR155HG,MIR944,MIR607,MIR1227,MIR9-2,MIR214,MIR339,MIRLET7I,MIR223,MIR302B,MIR940,MIR130A,MIR361,MIR874,MIR497,MIR155,MIR338,MIR9-1,MIR215,MIR187,MIR648,MIR24-2,MIR581,MIR450B,MIR31,MIRLET7G,MIR558,MIR143,MIR887,MIR33B,MIR194-1,MIR181C,MIR589,MIR126,MIR99B,MIR10A,MIRLET7D,MIR590,MIR383,MIR142,MIR452,DCP2,MIR30E,MIR186,MIR455,MIR643,MIR194-2,MIR129-2,MIR129-1,MIR29A,MIR502,MIR612,MIR578,MIR139,MIR611,MIR132,MIR626,MIR342,MIR96,XPO5,MIR490,MIR26B,MIR764,MIR210,MIR615,MIR150,MIR484,MIR330,MIR190B,MIR586,MIR133B,MIR661,MIR200C,MIR23A,MIR153-2,MIR185,MIR7-3,MIR605,MIR500A,MIR101-1,MIR920,MIR877,MIR216B,MIR125A,MIR20A,MIR107,MIR601,MIR335,MIR553,MIR7-2,MIR212,MIR922,MIR105-2,MIR153-1,MIR218-2,MIR206,MIR423,MIR16-1,MIR1-1,MIR147B,MIR551B,AGO1,MIR105-1,MIR149,MIR30A,MIR552,MIR190A,MIR147A,MIR21,MIR324,MIR375,MIR569,MIR598,MIR934,MIR618,MIR876,MIR140,MIR345,MIR296,MIR1-2 |
| 2.703e-28 | -63.48 | HSPA8 (heat shock protein family A (Hsp70) member 8) | protein interactions | 3312 | 2109 | 812 | 19454 | 5460 |
MAP2K1,PPT1,AKR1A1,LAP3,NDUFS2,TRA2B,SRSF2,PACSIN3,RCCD1,CD40,DDX39B,BMPR1A,DDX5,S100A11,PSMD14,KIAA1191,PELI3,RPS26,COP1,HNRNPAB,SFN,PSMA4,CREBBP,SNRPB,BTF3,TAX1BP1,MATR3,STAT1,PSMB6,PRMT5,PLS3,RPS7,RUVBL1,XPNPEP1,ROCK2,PSMA2,TFG,RPS4X,BCL9,DRG2,MAGOH,POU5F1,CBL,DDX1,WWP2,DCAF4L2,IFI16,CTNNB1,DDRGK1,YWHAG,SUMO2,SNRPD3,SNRPA1,HNRNPL,TTC9C,RAB1B,HSP90AB1,CCT7,CD63,ANXA4,SWAP70,DUSP6,PSME2,SIN3A,WDR82,HPS6,CD2AP,HDAC3,RPS15,RGS2,TUSC2,GRPEL1,METTL22,PIP4P1,PML,DPAGT1,DLAT,DERL1,RNF34,LSM12,TLR9,UBE2E3,RIC3,ATP1B3,UBE2H,RPL7A,MLF1,ST13,CFL1,CDC20,PSPC1,SEC61A1,PITPNB,HEY2,SRP54,CBX3,GNAI3,CAPN2,KIF1C,COMMD8,KBTBD4,ESS2,RPL17,SEPHS1,MEPCE,PSME1,MAP1B,AKAP8L,NUS1,DHRS7,RPS27L,CPNE1,LMAN1,ALYREF,DSTN,RAP1B,CRYAB,CFAP418,ACTL6A,CDKN1A,ATP6V1G2,PAFAH1B2,ATP6V1G1,AZGP1,PYGB,CSRP1,CFDP1,PSMA3,HSP90AA1,SLC25A42,ACO2,NIBAN2,SMARCE1,TAB1,ACTB,PRDX2,PRRC2A,ERH,CLIC4,LRRC28,SNRPD2,GDI2,RAB6B,SNRPE,RAF1,NAA15,CSNK1E,ERLIN2,PPP2R1A,CDK20,S100A10,SACM1L,RAD21,HNRNPA2B1,HSPD1,PCNA,VPS26A,ZNF207,ACTL6B,HYPK,DHX15,PSMB5,RPL8,USP46,KRT8,METTL14,HNRNPH3,RARS1,ARHGAP1,SF3A1,SYNGR2,CDK7,DENND2D,PIK3R2,GLIPR1,RPA3,MIS12,HMCES,MAPRE1,CDC73,RPL26,COPE,SH3BGRL,UBB,METAP2,TUBA1B,CCNF,ALB,MSN,RPS12,PPM1M,ACTR2,SERPINA1,TRIM6,FBP1,PGM1,VRK1,SFXN1,RAB1A,PPP1R12A,TLR4,ECD,CNN3,FNDC11,TSC22D3,CITED1,RPL12,RB1,PLAA,ADSS2,PIH1D1,FDFT1,OXCT1,TIGD7,FLYWCH2,SNRPA,HIRA,EP300,EMP3,LAMTOR1,GFUS,MLF2,ATP5F1B,TCAP,PPP5C,SF3B4,PIR,METTL21A,CRKL,RPL18,AAMP,ARFGEF1,RANBP1,ISG15,KRAS,CCT8,RTCB,DNAJB4,HSPB1,DRG1,MAPK4,PPIB,DYNC1I2,PAIP1,MACROD1,SRSF1,KCND2,HEBP1,MAGED2,RPA2,ACACA,HEXIM1,PPP1R8,NEK2,NAPG,NR1I3,EXOSC4,HNRNPH2,CALU,SLC6A4,PRKCE,KCTD9,MKKS,SRC,SUCLG2,SMURF1,MYG1,ZBTB33,RPS3,PSMC5,TFCP2,TFRC,MTCH2,UBL4A,TMEM33,CAPZA1,SLC25A11,SNIP1,RAB13,ERO1A,FAM187B,KCNJ10,USP15,RPS2,RBM17,KARS1,COPS5,RPS16,DNAJC1,TMPO,SSMEM1,ARMC1,STT3A,EEF1B2,TRAPPC3,CD4,ADNP,RNF7,PPARG,ATP5PO,H1-5,WDR77,KCND3,GK2,PRDX3,MCMBP,SKP1,FBXL4,CXCR4,DCTN3,TTC1,RNF10,NMRAL1,LMNB1,BLVRA,SP1,CUL2,GRB10,MCM4,RPL35,DYNLL1,SNRPB2,GNB1,PELO,UBE2S,RAN,CTSA,VAMP2,GTPBP1,GNB1L,SAP30,GFPT1,TRIM37,RBBP7,TRIM26,ARGLU1,TRIP4,SLC25A23,RPL23,CDKN1B,PRPF19,MAP3K14,WDR11,EIF3D,ERLIN1,CACYBP,PPP2CB,FOLR1,WDR6,GJA1,PCBP4,JUP,EPHX1,RPLP0,OXSR1,CCND1,RPS14,PSMC4,ELP3,CNP,HMGB1,SMC4,DGCR8,PRPF4,SYVN1,IVNS1ABP,SAYSD1,CHORDC1,NAPA,AAMDC,PPP1CC,YES1,ABHD17A,LDHA,EIF4A3,OPTN,STUB1,PTEN,CFAP298,RPS20,UBASH3B,GANAB,DTYMK,APEH,PDLIM4,SLC25A20,JCHAIN,DDX39A,EEF1A1,NECAP2,TOM1,THRAP3,CTNNBL1,PRDX4,MSH6,FBXO25,ARF4,NSDHL,PC,FBXO34,GMPPA,AMT,LRRC40,KCTD15,ALCAM,EIF4B,ATP6V1C1,MTF1,DUSP14,EDEM3,QTRT2,EEF1G,UFL1,SF3B1,CCT2,SERPINH1,HNRNPC,LDHB,MYC,BAG3,PSMD1,SSH3,ESR2,NCKAP1,APEX1,POLR2B,DLST,VDAC2,TUBB4B,HGS,DHX38,EEF2,NUDCD3,TUBA1A,HNRNPF,GXYLT2,PSMA1,RAB8B,CCAR1,GNA11,RPL31,EWSR1,SCPEP1,RPL6,LAMP2,CNOT2,EXOC1,XPO1,CHI3L1,FUBP3,HBB,DYRK2,BAP1,DDX46,LIN7C,ARFIP1,GLOD4,ABCG2,NUDT1,ETFBKMT,SLC25A1,CARS1,PSMB2,AKT1,SMARCA5,CTSB,IDE,CSNK2B,CAPZA2,INSIG2,RPSA,TP53,H3C1,NEDD8,AKAP12,PSMA5,RDH11,POLE4,DHX9,CLPB,SHC1,H2AC4,VASH1,MAP4,TPM3,GAPDH,TMED9,CAND1,FZR1,SSBP1,ACSL4,IER2,SKA2,VAPB,SLC25A3,ANXA7,ARCN1,FKBP10,IRF2BPL,DET1,CYFIP2,UCHL3,CMAS,CDSN,DNAJC3,TXNL1,BRCA1,YWHAZ,ILK,RPS5,PYCR1,TM9SF4,ATF1,CAPG,JPT1,AIPL1,TUBB,LGALS3,EIF4A2,JAK2,BORCS7,GPR37,BAD,GNG12,RPS9,SNRPD1,NME1,PRKAG1,PPID,RPN1,JPT2,STX12,RPS11,ARFGAP1,B3GNT2,JUN,FAF2,ACTN4,RPL29,SSRP1,AHCYL1,SCYL2,SLC25A5,BAG2,SRSF7,MRPS11,CDK5RAP3,COTL1,HNRNPD,PIK3R1,PDIA3,HNRNPA1,EGLN3,PSMB4,SDHAF2,COX6C,HAUS2,WTAP,SH3GLB2,WDR5B,UBLCP1,FBXW7,YKT6,PDHB,VPS28,DAD1,PIAS1,SOD1,INPPL1,PPM1G,DVL2,AP2A1,CNTNAP1,GMNN,NDN,GNAI2,VIRMA,ENO1,CTNNA1,CTTN,ZBTB18,MAGEA4,KLHL26,MLLT11,CCT5,TM4SF1,MAP2K3,HUWE1,PSEN1,FAF1,IGF1R,ERG28,PMM2,SPATS2L,DCUN1D1,CWC15,MRPS23,MDM2,TOMM70,CDK9,WDCP,DCK,DLGAP4,SIGMAR1,PAK2,MRPS18A,KLC2,RPL27A,NUP62,FUNDC1,STAU1,XRCC5,YAF2,AKAP1,HSPA8,CHTOP,DNAJB6,TBCE,CATSPERZ,HMGCS1,GPNMB,PSMD6,PSMD4,MTA2,MED9,SNX20,ERRFI1,POLDIP3,RPL28,PABPC1,RPAP3,RUVBL2,FKBP4,AGR2,YWHAB,DIRAS2,CST3,GSTM3,STK4,TCP1,FAM98A,ELK1,EED,SAMM50,VPS4B,PRKCA,UTP15,UBE2M,SPTBN1,CFTR,GABRA1,UBE2K,HSPA5,HCFC2,RNF113A,PRDX6,RC3H2,SPOP,SERPINB1,ATP1A1,PTPN11,SUB1,GSTK1,NAA50,MAT2A,ADRM1,GMDS,DHRS13,NMI,CSTF3,ROCK1,PSMA6,TSSK1B,SGTA,DNAJC2,GPD2,CHAMP1,RNF8,PHC1,CDK4,ACTR1A,TOLLIP,KPNA2,CCIN,NOSIP,IDH1,RPL3,ABCE1,TUBG1,AQP2,RPL10A,EDEM1,DNAJB2,CSNK2A1,CDC5L,ILVBL,SYNCRIP,MCL1,VAV2,NDUFA5,ALKBH3,ETF1,G3BP2,PSMC1,ATP5F1E,NOA1,CUL3,SAMHD1,RBBP4,RPL19,MAD2L1,CYB5R3,CPSF1,ZNF22,AP2M1,RMDN3,EZH2,OTULIN,CYB5B,ACO1,MARCKSL1,FEN1,WDR37,GNL1,ETFA,LASP1,RFC3,EIF2D,CPLX1,AP1M1,RNASEH2C,UBE3A,FHL3,PSMD10,AHSA1,MARCHF5,STOML2,PRDX1,PSMD3,MMUT,CCAR2,SNX1,RPL7,ATXN10,NOP58,PHB1,OCIAD2,DNM2,HP1BP3,GRM2,TOX4,SPR,TPT1,EIF3J,EDF1,CRAT,NUCKS1,EIF5B,CRYZ,AATF,CSTB,SLC2A3,FADS2,MME,MAVS,SQSTM1,TADA3,TXNIP,STK24,RETSAT,CSK,TUFM,GMPS,USP14,AR,NONO,RUNX1,ATP5F1A,RPL13A,TECR,CYRIB,PELP1,ACAT1,PRKRA,RAD23B,PPME1,ILF2,GGCT,PPIF,MAP1LC3B,SEM1,CTNND1,MRPL22,SLC25A10,EHD4,SEMG2,RING1,SEPTIN7,ZC3H11A,ESYT1,SLC2A1,TOPBP1,DNAJC7,ISYNA1,GMPPB,HDAC6,MAPRE2,G6PD,EEF1AKMT3,AIFM1,H2AZ1,SEC23A |
| 6.004e-28 | -62.68 | HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1) | protein interactions | 10075 | 656 | 314 | 19454 | 5460 |
PTP4A3,CDK9,DBT,MDM2,MAPRE2,TES,EEF1AKMT3,EIF4E2,SRP14,RPL12,PSMD7,CALR,EIF3E,PRDX4,PDE2A,RPS13,OLA1,POLL,HUWE1,LSM4,SEM1,HSD17B10,PC,HAPSTR1,MRFAP1,DLG1,ILF2,NDUFS3,RPL15,MAP2K3,PPARA,CCT5,RPL22,VIRMA,UBB,UBE2L3,RPL13A,COPE,ZBTB17,LDHA,GTF2A1,RTRAF,GANAB,EIF4A3,ENO1,CCNF,CCL1,CA2,SMAD2,TXNIP,NONO,AR,DNAJC8,TUFM,DEPDC1B,FBXO7,ATP5F1A,CTSD,UTP23,NUCKS1,HMGB1,FBXW7,RPL4,PDHB,NF2,RTN4,PPIH,PRKCB,IDH3A,SIRT7,RPA3,SOD1,SHOC2,RPLP0,METTL14,GRM2,HSP90B1,TOX4,CDK1,TPT1,EEF1E1,UBA52,PSMC4,SAP30BP,RPS14,SF3A1,PPIA,DIRAS3,HP1BP3,PHB1,RPL8,PDAP1,RPL23,MED4,VCPIP1,RB1CC1,AHSA1,HAX1,UBE2D1,CDK5RAP3,PSMD3,PRPF19,ANP32B,COPS4,MCM6,GTF3C3,SRSF4,PSMD12,TRIM37,GNL1,RBBP7,ERP29,RPS24,PCNA,HNRNPA2B1,SLC25A5,NEK9,TRIP4,HSPD1,GDI2,VAMP2,EZH2,ACTN4,FAF2,E2F4,B3GNT2,RAF1,TUBB,RBBP4,RPS9,IFT172,ARF1,FAM91A1,LSM14B,HSP90AA1,YWHAZ,BRCA1,BLOC1S5,MCM4,RFC5,CUL3,ACO2,UNC45A,PSMC1,RNF11,PXMP2,RP2,PSMA3,PMAIP1,CRY1,WBP2,SLC25A3,ADNP,PSMB7,RFXANK,CDC5L,TMPO,FZR1,RPS16,MCL1,EEF1B2,CD274,RPL10A,USP15,POLB,GAPDH,CAPZA1,GNMT,HNRNPK,CSE1L,KPNA2,PSMA5,RPL3,PAQR9,PSME1,MAP1B,PSMC3,FURIN,TFRC,H2AX,ACTR1A,TP53,KBTBD4,UBL4A,DYRK1A,PPP1R10,CDC20,ADRM1,BUB3,MACROH2A1,PSMC5,PHAX,PSMA6,ZBTB33,RPS3,UQCRC2,UBE2H,AP3S2,OAT,ATP1A1,ABCG2,TRIM23,RPS17,SUB1,RPL7A,SMARCA5,HSPA5,MARS1,KDM1A,DERL1,PRDX6,PGK1,LSM12,BAP1,RPL27,DDX46,KLF4,UBE2M,ZNF326,SSR1,RPRD1B,RPA2,CFTR,CD2AP,GABRA1,CCT7,ANKRA2,HSP90AB1,SNRPD3,SNRPA1,TCP1,SUMO2,HNRNPL,RPS10,EIF2S1,WDR82,MRAS,SRSF1,HSPB1,PEX3,DDX1,SMAD9,POU5F1,AGR2,AK2,NT5C2,CTNNB1,YWHAG,XPO1,YWHAH,RPL6,IFI16,RPS4X,RUVBL1,PSMA1,KRAS,PSMA2,PDIA6,RUVBL2,CCT8,CYP2C9,MOB3C,RPL18,CRKL,RPS23,PDHA1,HDAC11,TUBB4B,RPS7,EEF2,TOP3B,NCKAP1,ESR2,PPP5C,PSMD6,STAT1,PSMD4,ATP5F1B,PHF21A,SMU1,LMBR1L,DDIT4,PRSS1,FBXW11,PSMD14,ATG3,CKB,CCT2,KIAA1191,PCCB,SNRPB,UFD1,PSMD1,ATG101,LDHB,PSMA4,PAPOLA,MYC,CREBBP,PHB2,STAU1,EYA3,UBE2D3,SRSF2,EMC1,AKAP1,HSPA8,XRCC5,SNRPA,PIH1D1,PPT1,BET1,RPL27A,TOMM22 |
| 3.210e-27 | -61.00 | BAG1 (BAG cochaperone 1) | protein interactions | 573 | 466 | 240 | 19454 | 5460 |
ETFA,RBBP7,ANP32B,RPS27A,PSMD12,HNRNPA2B1,SLC25A5,SCYL2,ERP29,PCNA,NME1,GDI2,SNRPE,RPS11,RAF1,VDR,ANP32A,PPP2R1A,RPL7,DHX15,PPP2CB,PSMB5,PHB1,RPL9,RPL8,RPLP2,RPLP1,XPO5,PCBP4,PSMD10,PDAP1,BCL2L1,RPL23,HNRNPD,STOML2,SAV1,PRPF19,PSMD3,PDIA3,HNRNPA1,PSMC1,HADHA,PSMA3,ATP5PO,PGRMC1,WDR77,PRDX3,SIAH1,RBBP4,TUBB,AKR1C2,EIF4A2,ERH,RPL19,RAN,ENO2,CYB5R3,ARF1,SNRPD1,RPL37A,RPS5,HSP90AA1,TOMM40,HBEGF,SEM1,PTGES3,RPS13,OLA1,ARF4,HINT1,HSD17B10,RPL23A,ACTR2,RAD23B,ILF2,CCT5,RPL15,DDX39A,MAPRE2,AIFM1,RPL12,RB1,PSMD7,CALR,LRRC40,RPL4,PDHB,SOD1,RPA3,H2BC12,SQSTM1,HMCES,SYVN1,HSP90B1,CDK1,KRT7,HNRNPH3,MET,RPLP0,TPT1,PSMC4,RPS14,SF3A1,SLC25A4,RPL13A,TXN,COPE,LDHA,RPL22,SCML2,EIF4A3,STUB1,ACAT1,RPS12,CFAP298,TRIM27,GANAB,MAPRE1,CA2,NONO,AR,DNAJC8,GMNN,GMPS,TUFM,RPL26,RUVBL1,HNRNPF,CHCHD2,PRPS1,HNRNPDL,RPS4X,PABPC1,CCT8,DNAJB4,PDHA1,PLS3,METTL21A,RPL18,RPS23,RANBP1,PPIL3,RPS7,TUBA1A,ISG15,SNRPD3,TCP1,RAB1B,HNRNPL,COCH,CCT7,PEG10,SRSF1,KCND2,FKBP4,AK2,YWHAB,CBL,DDX1,RPL6,BTF3L4,YWHAG,YWHAH,EEF1G,TRA2B,XRCC5,FLYWCH2,PEBP1,DDX39B,HSPA8,PSMD6,MATR3,TAGLN2,PSMD4,RPL10,PSMB6,TOM1L1,CKB,CCT2,MDH1,DNAJB6,SERPINH1,RPS26,OSGEP,LDHB,HNRNPAB,BAG3,MLF2,PSMD1,CUTA,BTF3,KPNA2,PSMA5,RPL17,DHX9,RPL3,PSMC3,GFM2,COMMD8,TP53,ACTR1A,HADH,MIF,CAND1,ALYREF,RPL32,COMT,SYNCRIP,AKR1B1,KCNJ10,RPL10A,RPS2,PGAM1,RPS15,HSPA5,GRPEL1,THUMPD1,RPL27,PRDX6,IDH2,LDHAL6B,RPRD1B,GSTP1,PAAF1,CFTR,H2AB1,ADRM1,EIF4H,RPS3,PSMC5,QSER1,TRIM23,NIF3L1,OAT,ATP1A1,IGF2BP1,RPL7A,MORF4L1,RPS17,CFL2 |
| 3.987e-27 | -60.79 | LARP7 (La ribonucleoprotein 7, transcriptional regulator) | protein interactions | 51574 | 1090 | 467 | 19454 | 5460 |
SLC25A31,UBB,RPP25L,RPS12,HEXIM2,CMBL,EIF2AK2,ENO1,TUBA1B,POP7,MRPL53,CDC73,RPL26,LSM8,UTP23,BRIX1,MRPL20,MIR7-3,MIR34C,PPIH,MIRLET7I,MIR205,RPA3,PPM1G,RPL26L1,RARS1,UBA52,PIP5K1A,SF3A1,MRPL24,MRPS23,CDK9,NCBP2,CGAS,RPL35A,MIR25,PSMB1,ACTA2,KRR1,RPL12,BRD3,MIR34A,ATP5MG,GRSF1,MOV10,H2AC14,H2AC6,MRPS18C,NOC4L,HUWE1,RPL23A,TCOF1,NKRF,NDUFS3,LLPH,MIR15A,CCT5,H2AJ,ERH,MIRLET7D,MED17,TUBB,ACTB,PRDX2,MRPL23,RPS9,SNRPD2,SNRPD1,ENO2,HSP90AA1,RPS5,MIR363,BRCA1,ZCRB1,RPS29,MIR98,PRPF31,CYFIP2,PSMA3,SLC25A3,H2AC1,LARP4B,DHX15,RPLP2,PSMB4,MIR7-2,PSMB5,RPL8,RPL9,HNRNPD,MED4,VCPIP1,MRPS26,SKIC8,HNRNPA1,SSRP1,PSMD12,RPS27A,CDK20,ATP5F1D,BAG2,SRSF7,MRPS11,HNRNPA2B1,HSPD1,SLC25A5,SART3,SNRPE,RPS11,RPL29,PPP2R1A,RAF1,RPP25,FGFBP1,PHAX,CSNK2B,SRP54,SF3B6,PSPC1,UBE2H,IGF2BP1,MRPS16,CFL2,CFL1,RPL7A,PSMB2,SLC25A1,GRPEL1,STK38,RPS15,LSM12,RPL27,DDX46,MIR7-1,DYRK2,FGFR1,CD2AP,MIR34B,MIR429,MYL12A,MIF,MIRLET7G,RPS27L,CAND1,FZR1,CDK6,RPL32,ALYREF,SSBP1,MRPS9,LSM3,KPNA1,NOL12,H2AC4,RPL24,CHCHD1,E4F1,RPL17,MEPCE,MIRLET7C,HNRNPK,H3C1,MRPS33,MIR9-3,DHX9,MRPL52,MRPL33,DISC1,TP53,RPSA,STRBP,RPL10,ESR2,NCKAP1,PSMB6,CBX5,MRPL13,PRMT5,MIRLET7B,H1-1,RPS26,H2AZ2,MRPS25,CKB,CCT2,CIRBP,SNRPB,PSMD1,HNRNPAB,PSMA4,HNRNPC,MYC,EEF1G,PHB2,TRA2B,SRSF2,DDX5,SF3B1,RPS28,NUFIP2,MRPL12,GPC4,PSMB3,HSP90AB1,CCT7,MIR9-1,SNRPD3,SNRPA1,HNRNPL,RPS10,CDK17,PABPC1L,MIR221,MIR31,H2BC17,RPL6,WWP2,IFI16,DDX50,RPS4X,RUVBL1,PSMA2,HNRNPF,MIR206,MYO1B,EWSR1,CDK5,TRIM21,LSM14A,MIR9-2,RPL31,RPS23,H2BC1,TUBB4B,EEF2,RPS7,H1-3,MIR222,TUBA1A,DHX38,TRMT1L,RPL22,RPL13A,YES1,SLC25A4,TXN,RPS20,PRKRA,EIF4A3,MIR16-1,MIR145,PPP1CC,KPNA6,NONO,RUNX1,ATP5F1A,MBD3,RPL4,HMGB1,SMC4,GTF2I,NPM3,H2BC12,SIRT7,CSTB,PRPF4,MACROH2A2,RPLP0,ZNF574,GRM2,HSP90B1,H2AC7,LSM2,CDK1,MRPS34,MIR1-2,EEF1E1,MYL12B,SNRPN,PSMC4,RPS14,ZBTB2,ATP5PD,TOP1,MIR106B,AIFM1,H2AZ1,SRP14,HACD3,FGR,PSMD7,SNRPG,RPS13,MRPL22,HSPE1,THRAP3,LSM4,PC,HSD17B10,H2AC25,MRPL49,SRP72,ILF2,MIR17,MIR20A,RPL15,POP5,LBR,EEF1A1,MIR200C,MRPL11,RPL19,SNRPB2,RPL35,DYNLL1,RBBP4,RPL37A,FAU,ZNF668,MIR106A,SKP1,DNAJC22,COIL,PSMC1,HADHA,CCDC86,ATP5MK,MYL6,PDP2,ATP5PO,PPP1CB,PRDX3,H1-5,WDR77,RPL7,CCAR2,NOP58,HP1BP3,RPLP1,MIR141,PHB1,PPP2CB,RPL23,MIR1-1,CSTA,DDX23,EIF3D,TRA2A,ATG7,MRPS35,PRDX1,PSMD3,PRPF19,MRPS17,SRSF4,RBBP7,TRIM26,G3BP1,RPS24,PPAN,EIF1AX,SF3B5,TULP3,NUP153,SRPK2,RPL10L,MRPS21,MRPS28,PSMC5,ZNF330,PSMA6,RPS3,LSM6,EIF3G,ZSCAN25,RPS17,H2BC9,MIR29A,HSPA5,MIR107,MRPL41,MRPL40,HNRNPH2,THUMPD1,MIR10B,ACACA,HEXIM1,MIR21,GSTP1,RPA2,H2BC11,MRPL10,SURF6,CDC5L,DKC1,RBM42,RPS16,EEF1B2,SYNCRIP,USP15,RPL10A,CDK12,RPS2,SNRNP70,TSEN34,CSNK2A1,CMSS1,MIR16-2,H2BC14,CAPZA1,SRSF12,KPNA2,RPL3,MRPS18B,MIR200A,PSMC3,ACTR1A,H2AX,MRPL47,CDK4,SNRNP40,PSMD6,ATP5F1B,PSMD4,SF3B4,FTSJ3,H1-10,CHTOP,RPL39,MRPS7,STAU1,EIF1B,HNRNPA0,EP300,HSPA8,XRCC5,SNRPA,MRPS18A,RPL27A,TCP1,LYAR,DYNC1I2,MIR214,SRSF1,DRG1,MIR140,PPIB,MRPL9,MIR29C,MIR143,HNRNPDL,POLDIP3,RPL28,MIR155,CHCHD2,KRAS,H1-6,TRIM11,ACTR1B,RUVBL2,RBM3,PABPC1,CCT8,RPL18,ZRANB2,MTA2,SOX2 |
| 5.727e-27 | -60.42 | miRNA-mediated post-transcriptional gene silencing | biological process | GO:0035195 | 587 | 295 | 18204 | 5365 |
MIR9-2,MIR505,MIR363,MIR636,MIR611,MIR567,MIR640,MIR101-1,MIR24-1,MIR1298,MIR624,MIR145,MIR920,MIR191,TNRC6C,MIR23B,MIR205,MIR495,MIR615,MIR924,MIR599,MIR1296,MIR649,MIR208B,MIR98,MIR875,MIR616,MIR628,MIR129-2,MIR592,MIR361,MIR653,MIR23A,MIR7-1,MIR16-2,MIR105-1,MIR491,MIR141,MIR16-1,MIR338,MIR301A,MIR937,MIR424,MIR214,MIR802,MIR17,MIR502,MIR1180,MIR181D,MIR764,MIR222,EIF4E2,MIR373,MIR183,MIRLET7C,MIR1277,MIR552,MIR32,MIR581,MIR632,MIR657,MIR378A,MIR188,MIR873,MIR671,MIR133B,MIR34B,MIR583,MIR7-3,MIR1-1,MIR216A,MIR770,MIR139,MIR15A,MIR609,MIR143,MIR34A,NCBP2,MIR135B,MIR26B,MIR891B,MIR99B,CNOT8,MIR572,MIR765,MIR340,MIR155HG,MIR34C,MIR590,MIR147A,MIR148B,MIR586,MIR939,MIR140,MIR601,MIR769,MIR638,MIR137,MIR335,MIR28,CNOT7,MIRLET7I,MIR532,MIR194-2,MIR455,MIR181C,MIR422A,MIR934,MIR298,MIR652,MIRLET7G,MIR549A,MIR195,MIR1249,MIR542,MIR198,MIR874,MIR554,MIR29A,MIR100,MIR24-2,MIR193A,MIR944,RAN,MIR625,MIR30E,MIR922,MIR301B,MIR218-2,MIR106A,MIR711,MIR193B,MIR212,MIR551A,MIR563,MIR503,MIR618,MIR296,MIR218-1,MIR493,MIR153-1,MIR30A,MIR626,MIR346,MIR449B,MIR384,MIR604,MIR144,MIR192,MIR597,MIR639,MIR370,MIR331,MIR675,MIR1227,MIR612,MIR9-1,MIR877,MIR345,MIR30D,MIR578,MIR182,MIR1271,MIR517B,MIR374A,MIR367,MIR136,MIR25,MIR938,MIR600,DHX9,MIR569,MIR152,MIR92B,MIR99A,MIR147B,MIR595,MIR940,MIR9-3,MIR211,MIR1226,MIR29C,MIR500A,MIR200C,MIR425,MIR708,MIR187,XPO5,MIR339,MIR1260B,MIR125A,MIR573,MIR511,MIR450B,MIR936,MIR10B,MIR558,MIR488,MIR448,MIR1251,MIR551B,MIR20A,MIR631,MIR320A,MIR377,MIR656,MIR643,MIR206,MIR429,MIRLET7B,MIR221,MIR155,MIR130A,MIR489,MIR215,MIR492,CNOT6,MIR497,MIR223,MIR190A,MIR106B,MIR7-2,MIR3173,MIR216B,MIR942,MIR185,MIR605,MIR200A,MIR126,MIR302B,MIR553,MIR633,MIR1-2,MIR761,MIR484,MIR379,MIR184,MIR142,MIR490,AGO1,MIR556,MIR107,MIR190B,MIR186,MIR105-2,MIR885,MIR194-1,MOV10,MIR1224,MIR132,MIR449A,MIR589,MIR130B,MIR10A,MIR557,MIR1225,MIR607,MIR661,MIR101-2,MIR876,MIR204,MIR577,MIR423,MIR760,MIR593,MIR129-1,MIR452,MIR210,MIR454,MIR197,MIR150,MIR887,MIR33B,MIRLET7D,MIR196B,MIR548C,MIR330,MIR208A,MIR651,MIR662,MIR383,MIR31,MIR580,MIR504,MIR342,MIR148A,MIR324,MIR149,MIR375,MIR648,MIR519D,MIR146A,MIR96,MIR30B,MIR21 |
| 7.143e-27 | -60.20 | ANLN (anillin, actin binding protein) | protein interactions | 54443 | 1763 | 693 | 19454 | 5460 |
RPS17,RAP2C,DNAJC10,RPS3,ACOX1,BUB3,SRC,SRPK2,CAPN1,NEK2,RPRD1B,H2BC11,RPA2,CSNK1A1L,GSTP1,CORO6,BTBD10,EXOSC4,HNRNPH2,RBM22,MARS1,KARS1,LANCL2,RPS2,EEF1B2,STT3A,COMT,RPS16,TMPO,DKC1,MTCH2,CARD19,PALM2AKAP2,TCEA2,SLC25A11,MRPS18B,RAB13,CDC40,SRPRB,TMEM33,SRSF12,CAPZA1,MLF2,H1-10,FTSJ3,ICAM1,POLR1B,THOC6,FAM83B,SF3B4,BST2,ATP5F1B,SNRNP40,DES,CD59,SNRPA,RAP2A,RER1,SAP18,MRPS7,PPFIBP1,PPIB,UTP6,DRG1,HSPB1,SRSF1,SDC4,MAGED2,SUPT5H,AAMP,RPL18,TOP2B,CCT8,ACTR1B,RTCB,H1-6,CDC16,LRRC73,PPP1CC,LGALS8,NCKIPSD,VAMP3,EIF4A3,GLTP,CHCHD6,RPS20,RAB14,LDHA,YES1,RPL22,RPS14,SIPA1L1,ELP3,CNP,MRPS34,LMNA,JUP,TMOD1,RPLP0,PRPF4,ARPC2,H2BC12,GTF2I,SMC4,RPL4,HMGB1,MFN1,MPHOSPH10,MOSPD1,HACD3,SRPRA,SRP14,PWP2,PPP1R18,MTA3,MRPL11,EEF1A1,GNG10,RPL15,DLG1,PC,CAMK2G,PAK1IP1,THRAP3,RPS13,ARF4,MSH6,NOP16,TOMM40,RBM15B,MCM4,LMNB1,RAN,RPL35,DYNLL1,CHCHD3,GNB1,H1-5,WDR77,IDH3B,PPP1CB,ADNP,THOC3,HADHA,TMEM127,GPC1,COIL,SKP1,PRPF19,RAB3D,EIF3D,WDR11,TRA2A,RAP2B,CSTA,HBA1,RPL23,WDR6,FOLR1,THOC2,PPP2CB,KCTD10,ERLIN1,CACYBP,NUP153,GFPT1,CYB5R1,ASPM,CTSA,KBTBD3,GTPBP1,ARGLU1,PPAN,SRSF8,TRIM26,RBBP7,RFC2,RAB2A,RPL7A,CFL1,ARHGAP21,OAT,SORD,PSPC1,UQCRC2,PRSS8,GNAO1,PTPMT1,CDC20,GTF2H4,CDC42,CD2AP,RPL27,RBM23,SEPTIN6,PML,PGK1,DLAT,RPS15,FTSJ1,CLDND1,SMCHD1,SMG8,ALYREF,RAP1B,ADD1,DSTN,RPS27L,MIF,CBX3,GNAI3,NUPR1,CYBRD1,HNRNPK,MEPCE,RPL17,HNRNPAB,SFN,BTF3,SNRPB,MRPS25,RPS26,SMU1,PRMT5,RRAS2,MATR3,TAX1BP1,USP6NL,ZC3H14,LACC1,AKR1A1,CAV2,DDX39B,SPECC1L,DDX5,TRA2B,FXR2,NDUFS2,PHB2,PACSIN3,IFI16,RAB5C,YWHAG,CTNNB1,TNNC2,DDX1,HNRNPL,SNRPD3,SNRPA1,SUMO2,CCT7,HSP90AB1,H1-3,RPS7,PLS3,H2BC1,LIMD2,ABCF1,LSM14A,RUVBL1,RPS4X,CBLL1,HSPA14,RPL26,HMOX2,RACGAP1,METAP2,TUBA1B,TRIM27,RPS12,MSN,ALB,COPE,SF3A1,ARHGAP1,CDK7,METTL14,PICALM,RPL26L1,RARS1,HNRNPH3,RDH10,RPA3,KIN,BRIX1,ERCC3,MOV10,GRSF1,LAMTOR2,ECD,HRAS,RPL12,PTPN1,TES,RPL35A,SEMA3C,THOC1,MRPL24,ACCS,ACTR2,DTD1,DHRS7B,PPP1R12A,RAB1A,SFXN1,NKRF,RPL23A,CPNE2,CCNY,NOC4L,FARSA,PRPF31,RHOB,CNIH4,HSP90AA1,SNRPD2,LRRC8A,PRDX2,ACTB,ERH,ACTL6A,USP39,LARP4B,ISOC1,FEM1A,MFAP1,PRSS23,NOP53,AZGP1,KLHL7,RPL8,PSMB5,RPLP2,KRT8,SLMAP,PPIA,SRSF10,DHX15,CSNK1E,NAA15,PPP2R1A,ERLIN2,HSPD1,HNRNPA2B1,PCNA,DHX16,ASF1A,S100A10,GTF3C3,RAD21,FLOT1,MAT2A,RPF2,CDO1,GSTK1,UTS2,EIF3G,ZBTB38,ZNF330,EIF2S2,RALA,RPL10L,ADRM1,PPP1R10,ROCK1,SPTBN1,GTF3C4,CFTR,ZNF326,IDH2,SAMM50,UTP15,PRKCA,APMAP,BANF1,MRPL41,ZC3H15,HSPA5,CMSS1,CSNK2A1,TMA16,TMEM11,TMOD2,RPL10A,SYNCRIP,CDC5L,SURF6,H2AX,ACTR1A,HADH,RBM34,ARPC3,DNAJC2,NEFL,IK,TAF2,NOSIP,RPL3,SLC16A1,IMP4,TOLLIP,KPNA2,PAPOLA,CHTOP,RBM27,NSA2,DNAJB6,GTF2F2,USP16,TRIM29,RPL27A,NUP62,PABPC5,YIPF5,NCOA5,RFC4,SLU7,XRCC5,HSPA8,HNRNPA0,STAU1,GNB4,FKBP4,YWHAB,GNB3,CORO1C,EIF2S1,LYAR,TCP1,KIF2A,MTA2,PABPC1,RUVBL2,RPAP3,VDAC1,RPL28,HNRNPDL,POLDIP3,CTSD,NDUFB10,SEC13,ATP5F1A,AR,NONO,TUFM,PELP1,INPP5K,CYRIB,RTRAF,PRKRA,TXN,MAGOHB,RPL13A,TECR,SEC63,SAP30BP,ATG16L1,MYL12B,CDK1,HSP90B1,MME,PNO1,SQSTM1,MTDH,EIF5B,AATF,SLC2A1,ESYT1,H2AZ1,AIFM1,ARF6,TOP1,DBT,CAV1,YTHDF2,PPIF,ILF2,SRP72,ZC3H11A,SEPTIN7,HSD17B10,MRPL22,CTNND1,EIF3E,MDC1,CUL3,RFC5,MCM3,MYO6,CPSF1,PARP2,CYB5R3,RMDN3,AP2M1,RPL7L1,RBBP4,PARL,RPL19,MTX2,ETF1,MYL6,ATAD1,PSMC1,UNC45A,G3BP2,PSMD3,PRDX1,MRPS35,RSBN1L,LYZ,AHSA1,PHB1,HP1BP3,RPLP1,NOP58,RPL7,SPTAN1,FEN1,MAK16,RPS24,G3BP1,ETFA,AP1M1,RFC3,SMARCA5,SLC25A1,ARL6IP6,CFL2,MECP2,ABCG2,IGF2BP1,PDCD4,MACROH2A1,DAPK3,DYRK1A,LUC7L3,CSNK1G3,DDX46,NLE1,TNFAIP1,WDR3,PPIL4,GAPDH,TPM3,RPL24,KPNA1,MAP4,ITGA6,MRPS9,SSBP1,ACSL4,RPL32,GATAD1,FZR1,MYL12A,IMP3,STRBP,FAM162A,RPSA,CAPZA2,BIRC5,SLC25A24,DHX9,PSMA5,H3C1,CSE1L,MYC,APOBEC3B,LDHB,HNRNPC,CCT2,RPS6KA4,RCL1,SERPINH1,VDAC2,DLST,POLR2B,APEX1,RPL10,ESR2,GSTM2,NUFIP2,EIF4B,CSNK1A1,NGRN,CCDC9B,RPS28,SF3B1,EEF1G,DDX50,BAZ1B,RPL6,XPO1,YWHAH,NGDN,QPCTL,KCTD20,RPRD1A,PABPC1L,RPS10,NOB1,TRMT1L,DHX38,EEF2,TUBB4B,PDHA1,TAF10,RPS23,GNAQ,GNA11,RPL31,EWSR1,TRIM21,MYO1B,PSMA1,HNRNPF,CCAR1,ASCC1,AP2A1,PPIG,CTTN,EIF2AK2,CTNNA1,ENO1,TMOD3,VIRMA,GNAI2,STOM,WTAP,PPM1G,PDHB,COL3A1,VPS28,SPATS2L,POR,KRR1,CGAS,CDK9,MRPS23,CWC15,CCT5,MAP2K3,CD2BP2,EXOSC8,MAGEA4,TOPORS,HUWE1,SMN1,PKP4,PYCR1,MRPL16,RPS29,YWHAZ,BRCA1,CCDC25,RPS5,LSM14B,GNG12,TRMT6,SNRPD1,RPS9,EIF4A2,RANBP6,TUBB,RASL12,VAPB,ARCN1,SLC25A3,EMG1,SRI,CMAS,RAB32,HMGA1,HNRNPA1,WDR12,MRPS26,HNRNPD,RPL9,MRTO4,AGK,HSDL2,RPL29,ACTN4,RPN1,EXOSC3,RPS11,POLR2C,SART3,SLC25A5,SRSF7,BAG2,RPS27A,SSRP1 |
| 1.047e-26 | -59.82 | organelle membrane | cellular component | GO:0031090 | 3742 | 1357 | 19108 | 5553 |
TOMM6,DAD1,TIMM8A,CPLX3,RHEB,RBMX2,TLR6,RCE1,RAF1,MRPL52,ABHD12,ROMO1,GPNMB,INPP4A,MPV17L2,VPS33A,RAB2A,SLC25A45,NUP62,SLC18B1,RHOG,EMC2,BECN1,MAP1LC3B,COX4I2,SNX3,BORCS5,HUWE1,PPIF,CORO1C,TMED5,TMBIM1,MRPL40,VPS4B,RAB30,TF,HSD11B1,PLPP6,MBLAC2,IMMP2L,TMEM208,SLC2A3,ATP6V0E1,CDC42,GNAQ,ST6GALNAC3,TMEM199,UBE2D3,STOM,ORMDL1,CSGALNACT1,CPT1B,MGST3,JAGN1,PLN,VAMP8,SCD5,CAV1,SLC25A14,LITAF,UQCR11,TESPA1,SMCP,MTX2,SLC25A39,SAYSD1,CAV3,DNAJC1,GALNT4,REEP3,TMEM177,TMED9,TMED1,EPHX1,ADCY3,HACD3,NCK1,H2BW1,BBS5,YIF1A,PYURF,ABCG2,BET1,ATP5PO,TMEM231,LMAN1,SLC25A51,FZD6,USP30,ATRAID,KDELR2,GALNT17,CYB5B,CSGALNACT2,YWHAB,CYP2C18,GJC1,CREB3L4,CHST7,TRAPPC4,SV2B,TMEM50B,PIGY,VDAC1,SLC25A3,CYP27B1,UFL1,YIPF5,ST6GAL1,ZDHHC17,RAB23,PIGK,RPS29,UQCRQ,CDK1,FZR1,SESN2,RAP2A,RAB22A,DNAJB2,GABRB2,ATP1A3,RAB3C,SVIP,TYROBP,SEC61B,LARGE1,CLCA1,CD63,SLC25A26,NDUFAF2,DECR2,AZIN2,SPTSSA,TRIQK,TLR1,VAMP3,HACD4,CMTM6,TMEM95,DMPK,PRCP,MRPS11,KLC2,CLIC4,PIP4P2,PITPNB,GGTA1,RNF26,SLC17A5,CHMP5,AP5S1,MRPL23,TAFAZZIN,SAR1B,CALU,CLVS2,CNP,SLC25A31,TMEM203,PEX3,MARCHF5,SNX33,GAL3ST1,HS3ST3A1,NDUFB6,CHDH,BCS1L,ADCK1,ROCK1,PEX5L,NUDT1,SMAD3,MRPL20,TAB1,HINT2,CYB5R1,NLRP6,EXD2,SACM1L,SELENOI,UCP2,MIA2,NUP50,TAPBPL,PIK3R1,RTN4,DIPK2A,TMX3,SNX12,MGAT1,SNX1,SURF4,UBAP1,RAB4A,MME,CD3G,MAP1LC3A,FAM20B,SEC62,NDFIP1,STARD3NL,SNX18,CNIH4,TMED7,VLDLR,C9orf72,AP1M1,TSPAN15,SELENOT,DNAJC30,NDUFS3,TECR,TMEM174,CALR,APPBP2,GLE1,SELENON,CFTR,CIBAR1,CD1B,PRICKLE2,HAX1,CYB5A,MRPS35,ARMCX3,EDEM1,SLC30A5,PROM1,MAD2L1BP,HBEGF,PIP4P1,NDUFAF3,EMC9,CYP7A1,RHOB,MGST2,DDRGK1,CDIPT,BAD,RRAS2,DIO3,ALPL,NRP1,FMO1,GNPTG,SLC32A1,SYT4,APOO,SYNRG,LRRC8C,ATP5F1D,MRPS34,SLC25A42,OTULINL,SDR16C5,NOTCH2,SLC25A27,HSPA8,LAMP3,FCGR1A,SPHK2,MOSPD1,AP2M1,GRPEL2,SYNGR4,RETREG2,SYNJ2BP,MRPL41,DRAM1,VPS4A,SPPL3,CD38,GPR37,VPS39,DUSP18,ARHGAP1,OPTN,FAF1,MPV17,ATP6AP2,SLC2A8,CERS6,UST,SNAP23,ATG9A,B3GALT1,TPST1,SPG21,MCL1,WDR3,SC5D,TMEM74,IRF7,RINT1,FCMR,TOMM22,SNAPIN,GDE1,GLIPR2,CPT2,ELOVL1,DPAGT1,TMEM45B,PTPN5,SELENOS,GNA11,PTGES,LRRC8A,B4GALT3,RPS28,SIGLEC5,DUSP21,TMEM106C,GJB1,CASP4,PGAP2,TSG101,ALG5,MPDU1,FLOT1,GAL3ST4,CDK4,CTSC,DPM2,COG1,SLA2,DHRS7,SSR3,SYNPR,RAC2,TOM1,TMEM176B,DOLK,ZMPSTE24,MOSMO,SGMS1,COX8A,PAQR3,MRPL9,GOLPH3L,GOLGA7,COPZ2,COX6A2,OSBPL8,NCSTN,HYAL2,ENTPD4,NLRP3,TIMM17A,SNX20,UBAC2,RAB5A,NOS1AP,QTRT2,COX5A,NPC1L1,TMED4,TRIM27,NDUFA2,FAXDC2,MRPL47,ALG2,KLK6,VAMP5,CYP4V2,EHD1,RNF139,CARD19,TRMT10B,XXYLT1,ARCN1,SLC15A2,B4GAT1,MRPL18,PLP2,CYBRD1,LRP6,TRIM23,NGRN,CYP1A1,EXOC3,TMEM126B,CHCHD1,LBR,SLC31A1,COQ10B,ATP1B1,GALNT12,GPD2,ATP6V1C1,NDUFAB1,VPS26A,TIMM21,LAMP2,SEMA4C,SEC61A1,FAM162A,SNX24,FAF2,AQP4,ZDHHC16,WDR83OS,BST2,RETREG1,NDUFV2,FLRT2,CYC1,PPP1CC,TMEM168,MRPL36,CYP11B1,GCNT3,SCG3,SPTSSB,STIM1,TMEM33,GALNT1,TRAPPC3,ATP5F1E,LAMP5,RND2,CALY,STX18,SNX14,TRAM1,ATP1A2,MGAT4A,ARMC1,UQCRC2,TAPBP,SEC22C,BSCL2,PCYT1B,RPL27,FA2H,GK2,UQCC6,B3GALT2,TAPT1,GAPDH,AKAP1,DERL1,USP8,GOLGA5,NDUFB7,GDPD3,SEC61G,DTL,KPNA2,NUP35,CAV2,CD36,CHST9,ST3GAL5,ELOVL7,TMEM160,ATP5MC1,ST8SIA4,COX20,SLC12A2,SPCS1,VAMP2,ANXA4,TFRC,MRPS18B,CHMP4C,SNX10,TOMM40L,PTGDS,AQP2,SVOP,NDUFAF4,PYCARD,PLSCR3,GLCE,MINDY3,HS3ST5,MAVS,QPCTL,BNIP3L,HSD17B6,FAM8A1,RPS26,PTDSS1,TICAM2,TMEM190,MTG1,PXMP2,TMEM167B,RPN1,NDUFC2,MTHFD2L,CHST10,FZD4,TRAF6,SLC25A11,PDIA3,DBH,MRPL34,STARD7,MRPS28,GLIPR1,MX1,CYP17A1,COX7B,PICK1,MRPS25,REEP4,STX10,EMC6,STT3A,RAB11B,ATP5F1A,UQCRC1,MGAT5B,EMC1,ZDHHC4,CHRM3,TERB2,CACNG3,STX5,HSPD1,RAB32,CD58,MAIP1,MRPL33,SEC22A,CYP11B2,SNX17,CIDEB,RAB3D,RAB6A,DERL2,MRPS18C,GABRG2,LDHB,MYORG,SEC11A,CYP4F22,RSAD2,LY96,ATP5MK,PIGW,STK26,MRPS18A,THBD,OPRK1,GORASP2,TMEM70,PARM1,REP15,REEP6,SNX22,WTAP,PXYLP1,SNX2,PRNP,SRI,ELOVL3,RP9,GPR37L1,SLC7A14,LRRC8D,NDUFS8,MRC1,NRM,LST1,CLVS1,SERPINB6,MOXD1,TIMM8B,CYTH2,SLC35B3,GRPEL1,PGAP4,TMEM179B,MINAR2,SLC35A2,RB1CC1,KDSR,PNPLA8,LGALS3,TMEM97,TMCC1,MIEF1,RETREG3,NDUFA1,CPE,SYNGR3,EEF1A1,SFXN1,FUT8,GABARAPL1,SLC41A3,GABARAP,SLC25A20,SERINC1,VMP1,CHCHD6,RAB6B,RAB11A,CBX3,CHPF2,STBD1,UNC50,ACP2,RAP1B,PSEN2,FLRT3,HAS3,C1GALT1C1,TENT4A,ILVBL,IRAK4,PML,BACE1,PDCD10,GAD2,TNKS2,FCER1G,ELOVL4,TMEM38B,TMEM39A,ARFGAP1,MGARP,MSMO1,COX6B2,GASK1B,RDH10,CYP4F12,SYS1,CYP39A1,GPAM,MRPL57,USP6NL,DNAJC25,TLR7,LAMTOR2,B4GALT4,ST3GAL4,STARD13,MFN1,NCALD,APEH,VAMP7,GTF3C3,PAFAH1B1,TOR1B,SEC63,ATP5MG,TUFM,OR51E2,EMC4,PDE6A,FITM1,CNR1,PLCB1,DRD1,ELK1,NOC4L,FABP5,LRRC8B,B4GALT6,MRPL16,PHB2,FITM2,LMBRD1,MACO1,CRAT,PRRT1,CYB561D2,PMPCA,SPCS3,IZUMO1,VPS16,B4GALT7,MRLN,WSCD1,TWNK,LEMD3,RAB37,MTG2,TNKS,COX4I1,DIPK1A,ZDHHC14,SMAD1,MTMR2,ARHGAP21,TEX261,TUSC3,EMC8,MRPS16,MIOS,EMP2,DPP4,FADS2,SLC25A21,IL15RA,PDE6D,TMEM59L,CTSA,NECAP1,UBB,STX6,RNF152,TMEM106B,TAB2,VKORC1L1,CLPX,ATL1,TM9SF1,PGR,OST4,HHIP,GABRB3,FAR2,PARL,ATP6V0B,DEGS1,PDE2A,ST3GAL1,RPS27A,SYBU,LYSET,ABHD17A,RAP2B,CCNI,RAB39B,NAPG,TBC1D24,RETSAT,LILRA3,AFTPH,RAB8B,SRPRA,PLEKHF1,MTDH,SNAP29,KCNA2,ATP2C1,BPNT2,SYNE4,RNF167,DKK1,SLC35C1,GNB4,NDUFB4,RRAGA,FMO3,FKRP,ZFAND2B,TIMM10,TMED3,CTSD,SLC11A2,NDUFB5,VTA1,BCL2L1,GCC1,SLC25A1,MARCHF3,TOMM20,NECAP2,ARF4,CD14,TLR8,AP3S2,PRKCA,FKBP1A,OSTM1,MGAT4B,ALOX5AP,TMCC2,CYP2R1,PSENEN,SIGMAR1,WDR11,RAB1A,COX7B2,SNAP25,CYP4F8,GPR137,FKBP1B,CH25H,SNN,MYO1B,DLG4,VAC14,ZDHHC8,G6PC3,DUOXA2,MATR3,UGCG,CLBA1,SLC25A24,CAMLG,SYT2,B3GALNT1,TMBIM6,SLC25A23,TYMS,FIG4,CHMP1A,ATAD1,DLG1,MYO6,JPH4,EI24,FAM169A,ATG101,STX16,CX3CR1,HIGD2A,WDR83,LPCAT3,ERLIN2,CD4,DNAJB9,SLC39A7,ITGAV,MEST,CYB561,SAMM50,GABBR1,TMEM59,TMEM14A,FAM20C,SLC2A1,MRPS26,COPE,HMOX2,PLEKHA8,NEU1,ATP5PF,FLCN,CD1C,RIC3,SYVN1,KGD4,SLC37A4,STK24,TLR4,LDLRAD4,CXCR1,EIF5A2,MREG,MCHR1,CHST1,OLR1,ATP6V1A,CHMP1B,B2M,RMDN3,SLC38A9,PIGC,TRA2B,HADHA,TMT1B,INPP5E,TOM1L1,SCYL2,SFTPD,SLC4A8,CD47,AP2S1,CLIP3,TAMM41,TNFRSF1B,CREB3,NAA60,FKTN,RRAGB,SFTPC,ABCB9,FCAR,AGPAT5,ATP6V1D,SPRED2,PTRH2,MRPL50,LMNB1,BFAR,GNAI3,ERLIN1,BAX,CYBC1,LMNA,RNASEK,UGT1A1,AP2A1,POR,TBC1D5,COX6B1,SLC35D1,OCRL,WNT7A,CD1E,PDIA6,B3GALT4,MRPL10,TRIM37,CAMKV,CISD1,CD1D,CASK,CCND1,TMX2,KXD1,SLC35F6,EFCAB7,MRPL12,MRPL49,CYP27A1,VPS28,MITF,CYTH1,AQP11,COQ8B,COX10,KRAS,STX12,CNIH1,MMD,AGK,TM4SF20,ARMCX2,SORD,RND3,TLR9,TRAPPC3L,FUT1,LYPLA1,XPO1,HM13,DHRS4,SLC35A5,LAPTM4A,GNPNAT1,APH1A,TMEM126A,RALA,GNB1,ARF1,PDSS2,THG1L,SCAMP5,ACSL4,MRPL24,ARFGEF1,BRAP,TMEM170A,SERPINA5,RAB5C,AGPAT1,PGRMC1,SYN3,TVP23B,GHITM,ENO1,STOML2,SGMS2,CHCHD3,RAB35,STX1A,SERPINB10,HTRA2,CDIP1,RAB9A,TMEM87A,FIS1,SLC25A28,CHMP2A,MCOLN1,CHST2,NTRK2,RHOBTB3,SEC61A2,PEDS1,SUMO1,POMT2,DCAKD,HRAS,TMEM165,SEC13,FUNDC1,SLC25A12,TIMM23,MAN1A2,EXTL2,ENPEP,NUP153,KCNH1,RAB27A,TBC1D10C,GPAA1,LMBR1L,TLR3,NDUFS2,NDUFA4,TRAF3IP3,TMEM11,ATP1A1,CERS2,PEX26,LAMTOR1,NUS1,PSKH1,TICAM1,PEX13,SLC1A1,XBP1,SLC39A13,SEC23A,NUDT9,ATP6V1G1,CYTH4,PLD3,GPR89A,CHMP2B,CD1A,STX17,DIO1,SLC25A44,SRC,CYSTM1,CLSTN3,B4GALT1,GRIA2,HGS,CD164,NFE2L1,CD46,GRIA1,BET1L,RNF103,FGD2,CCDC90B,MRPS17,RAB33B,CYP3A5,MT3,MRPS7,OS9,CYB5R4,SARM1,PGAP3,HS2ST1,TAS2R46,SSR1,SGIP1,INSIG2,DNAJC19,SLC30A7,TSPO2,NUP42,TOMM70,RNF5,KICS2,GOSR2,SLC35G2,SFXN2,ANXA7,SFTPA1,SLC25A17,COX14,ZNRF1,SDHB,SMDT1,SLC25A32,AGTRAP,NSG1,HSP90B1,UBXN6,NDST3,SDHC,DELE1,ST3GAL2,PHB1,GCHFR,BORCS7,CAMK2G,TOR1AIP2,TEX264,FUNDC2,NDUFS6,ATP5F1B,TOMM7,RHOBTB1,DNAJC2,PSEN1,RAB14,CASC3,GABARAPL2,LAMTOR3,SLC25A4,CD9,STX7,ABHD6,FUT9,ESYT1,CYP2D6,MRPL53,ALG11,COA1,CLN8,RDH11,SELL,SYPL1,SERPINA1,MRPS21,MRPL11,RAP1A,ABHD4,ATP5PD,ICA1,ARFIP1,AIFM1,TRAM2,SYNGR2,BCAP29,SELENOK,UQCRH,NUP107,CYP1B1,BORCS8,NCDN,RAB18,ACER3,VTI1B,BOK,FDFT1,BCL2A1,GABRA2,TIMM29,RNF121,LRAT,MRPL22,CYB5R3,VDAC2,CHPF,CHP1,ITM2B,EPHA4,ACOX1,COX7A1,NOA1,PTPN1,FKBP8,HSD17B3,MRPL13,BLOC1S2,NDUFAF6,CYP21A2,SNX5,EMC10,PGS1,FATE1,SLC48A1,MYRF,EHD3,KDELR1,ATP5PB,TRAF2,RGP1,IFI6,EFHD1,NME4,B3GNT2,CYP2C8,JKAMP,MRPS33,ARL6IP6,RAB33A,RAB3B,PIGA,EVA1A,SLC52A3,NOSIP,SH3GLB1,CD274,SEC22B,PROS1,TLR2,TMEM14B,NDUFA5,LDLR,WDR44,AP1S2,ERG28,SLC25A10,HACD1,FKBP2,MPC1,VAPB,ADRB2,GOLGA7B,DHRS7B,DNAJC5,SRD5A3,HSPA5,PDLIM4,IFI27,SRXN1,RTCB,FCGR2A,TSPO,COX11,UBA52,CPTP,VPS54,SLC39A9,ABCC5,CHST13,AP1G2,SLC6A4,DYNLL1,CYP26A1,ARFGAP3,TFE3,TASL,MARCHF4,ADRA1A,FURIN,CYP2F1,COX6C,ERO1A,ARMCX1,ATP6V1G2,NDUFA12,SHISA2,TTC8,RHOU,EHD4,SDCBP,SLC35B4,RAB9B,RER1,GALNT2,TRAM1L1,PREB,LHFPL2,USE1,TMX4,FMO2,SCFD1,TMEM115,SLC22A17,ACAP2,RAP2C,SLC51A,HACD2,SLC25A46,RNF144B,YKT6,TMEM108,TIMMDC1,CLU,ENPP4,VAMP1,SYP,AP5M1,UQCC3,CD59,WASL,MRPL17,AHCYL1,BORCS6,MTCH2,FGR,MDM2,ORMDL3,TIMM13,PCDHB13,SYNDIG1,FOLR1,NSDHL,MARCHF9,SEPHS1,AURKAIP1,SRPRB,RPS3,NDUFB8,CYP3A43,KLHL12,ZBED1,RNF133,GNPAT,ATP8A1,SPCS2,PLA2G4B,PCSK9,CPNE1,ATG16L1,TOMM40,ST8SIA5,CHST11,TLCD3B,UQCC2,RAB3A,COX16,PTPMT1,PAK5,GGCX,SERINC3,PMAIP1,MRPL51,MRPS9,CD2AP,ZDHHC15,EXT1,SLC35A1,GJA1,CCDC47,NDST1,SCAMP2,THAP7,DHRS3,RAB13,TFEB,PLAAT3,UBIAD1,PLEKHF2,BAK1,SSR2,GABRA1,ATP5MC3,ARF6,SLC25A5,DNM2,MUL1,MTARC2,BRI3,CYP2C9,CLCN6,TTC1,C2CD2L,ARL6IP5,ELOVL6,MOB4,RAB31,RDH12,NDUFB10,TMEM147,OSBP,HPS6,MRPS23,SLC35F1,SYNGR1,SLC38A7,GOSR1,TMEM30A,RAB1B,MYD88,UFD1,VPS18 |
| 1.477e-26 | -59.48 | RNA binding | molecular function | GO:0003723 | 1976 | 800 | 18094 | 5411 |
RPL9,PIWIL4,DTD1,MIR34C,RTN4,CPSF1,NOL7,RPL28,RPP21,ZNF622,MIR92B,DDX39B,SLC25A5,SPATS2L,MIR638,RPS11,MIR379,RPL15,MIR640,TLR7,MIR211,SRSF10,MIR129-1,PSPC1,MIR3173,RNASEH1,DUSP14,HNRNPD,TIA1,OAS1,MIR495,LSM8,HNRNPH3,SURF6,TNRC6C,EZH2,MIR193B,MOV10,SMN1,MRPS17,ADD1,CARHSP1,DXO,CARS1,MIR383,SRPRA,SIN3A,MIR215,AHCYL1,MIR126,RAMAC,AGO1,SNRPB2,NPM3,PIWIL2,HSP90AB1,AKAP17A,RBFOX3,XPOT,ZNF326,TUFM,RPS27L,UBFD1,HMGA1,TCOF1,SF3A1,KIN,TENT5C,WDR3,NCOA5,GTF2E2,TST,EEF1A1,ZYX,DTD2,MIR194-1,SMG5,CCT5,CPSF4,RBBP7,JAKMIP1,EIF3G,HMGB1,PRPF31,MIR181D,MIR657,MRPS23,UBE2L3,ROCK2,MIR374A,RPS3,MIR302B,EIF3E,MIR23A,MRPL11,TES,HSPB1,ILF2,NABP1,ARCN1,PABPC1,RBM15B,EIF4H,SSRP1,MRPL16,HNRNPA2B1,EIF3D,NGRN,NUDT4,EIF3K,XRCC5,MIR340,SUPT5H,SAP18,MIR335,MIR572,PPP1CC,THOC1,MIR142,MIR146A,VIRMA,PCBP4,SNRPA,EP300,HSPD1,CSRP1,MIRLET7C,HNRNPK,RPL4,ADK,RBM12,CCDC9B,CDKN2AIP,G3BP1,NLRP6,MIR137,TRMT1L,FUBP3,SECISBP2L,LSM2,H1-10,MIR455,RPL7,EIF1AX,MRPS35,MIR429,SLC25A11,MAP4,LSM12,GRSF1,THOC6,MIR330,RPL19,IFIH1,RPSA,LGALS3,MARS1,RPL23,BRIX1,MIR345,RBM7,MIR223,TLR9,RBMS2,COIL,H1-5,MIR148B,MIR214,RNASEL,MRPS18C,MIR505,UTP15,AKAP8L,PRRC2A,DGCR8,MIR185,DCP2,RBM38,MIR181C,RBMX2,MIR497,NONO,POU5F1,THUMPD1,RPL32,SNRPD2,CELF6,NR0B1,EEF2,TP53,FAM133B,SEC63,EIF5B,SRP72,MIR140,BUD23,PSMD4,RPS13,G3BP2,MIR346,NOP58,SNRPN,LLPH,RBFOX2,HUWE1,PAPOLB,SNRPD1,RPF1,EIF1AD,FYTTD1,MIR15A,MIR153-1,RBM42,ZCCHC7,ATXN1L,MAK16,ASCC1,IFIT2,SMARCE1,MIR192,TSNAX,RPL39,RPF2,CCDC86,RBM3,MRPL10,PNO1,PDAP1,APEH,EMG1,SUB1,MIR99B,MIR16-1,RTRAF,MIR449A,RPS12,PABPC5,CNOT8,MRPL24,UTP23,FTSJ3,NUDT5,MIR1224,UBE2I,QTRT2,DROSHA,MIR205,MSN,TRA2B,KDM1A,ARB2A,MIR26B,ELAVL4,MIR187,TRMT11,METAP2,EIF2S2,SYNCRIP,RPS24,NLRP1,ANP32A,MIR150,ZC3H15,CALR,BTF3,FARSA,NUFIP2,DDX5,STRBP,RPS20,PPP1R10,EDC3,MIR877,MIR130A,JUN,NUP42,SNIP1,LBR,MIR20A,LYAR,ADAT1,GEMIN7,RIGI,RBM22,SAMHD1,TRIM21,CPSF2,CRKL,FAM98A,UNC50,SNRPA1,LSM4,MIR876,WBP11,GTPBP1,ZC3H7A,TYMS,DHX9,RPS7,EIF4A3,EIF2S1,SRSF12,YWHAZ,RPL35A,MIR874,PCSK9,KHDC1,SNRNP70,MIR1-1,MRPL12,UTP6,POP5,APOBEC3B,TRIR,RPS16,PSMC1,MIR191,THG1L,MIR208A,MIR661,MIR491,HNRNPDL,KCTD12,MRPS28,MIR183,RPL13A,MIR208B,TRIM32,PPIL4,ACO1,CRYZ,MRPL23,NOA1,NOVA1,AKAP1,DNAJC2,RPP25,RPL7A,MRPL13,DHX16,NHP2,HEXIM2,CMSS1,TACO1,MIR363,MFAP1,MRPS11,ZCCHC9,MPHOSPH6,POLR2B,CTNNA1,NOL12,MIR296,PPIB,CDK9,HSP90B1,MIR493,MIR21,CSTF2T,DHX38,RPS15,MIR100,RPS10,RTCB,FLYWCH2,POU1F1,MIR125A,TSN,MYEF2,PEBP1,LUC7L3,LSM6,MIR10A,RPS4X,PPAN,HNRNPF,APEX1,MIR96,POLR2G,HNRNPA0,RPS27A,APOBEC3C,MDM2,MPHOSPH10,NSA2,PPP1R8,H1-3,PPIG,RPL24,SNRNP40,CDC40,TERT,NKRF,NUDT16,MIR30E,CHTOP,LSM10,MIR99A,RPL8,BOLL,DICER1,TFB1M,TDRD7,MIR221,MIR106B,EXOSC1,MIR190B,MIR212,MIR384,DDX39A,FKBP4,MIR206,STAU1,CSTF3,MIR503,UBE2N,MATR3,MIR423,ZCRB1,TUBB4B,MIR708,RP9,MIRLET7G,EIF4B,MAGOHB,MIR639,MIR361,WRAP53,RBM5,ISG20L2,RPP25L,CASC3,MIR488,HNRNPL,MIR519D,RBM27,MIRLET7I,PPIA,SUMO2,MIR675,MIR107,EWSR1,THRAP3,PIWIL1,SPTBN1,PABPC1L,TYW5,IFI16,ELAVL2,MIR1271,MIR873,CNOT7,TOP3B,KARS1,BRD3,MIR378A,RAD21,IGF2BP1,KRR1,BCCIP,MIR338,HNRNPAB,CYFIP2,PAIP2,SRP14,MIR210,MIR425,SNRPG,RPS14,PAPOLA,MIR29A,TRA2A,RPL35,SF3B4,RPS9,SOX2,CPEB1,LARP4B,ZRANB2,RPP14,RPL27,EIF4E3,PSMA6,SUMO1,MRPL41,RPL23A,PAIP1,MIR28,SRSF4,MRPL22,RBM34,LSM3,MIR30B,MIR144,RALYL,KHDC4,RPS28,ZC3H11A,SF3B5,HENMT1,ALYREF,RPL31,NUDT7,RNASET2,APTX,SRSF1,DHX15,MRPL9,PTPN1,PRKRA,ALKBH5,SERPINH1,PRDX1,MIR148A,MIR9-1,ETF1,DRG2,LSM5,HSP90AA1,MAGOH,MIR222,MIR552,SEC61B,RADX,CCAR2,NTPCR,MIR182,PAX6,NOSIP,MIR492,SNRPE,NME1,MIR106A,TCP1,ELP3,MIRLET7B,RPL27A,UTP25,MIR143,IMP4,MIR141,MIR590,FASTKD5,ACTN4,NUCKS1,MIR149,NOP9,PWP2,GTF2F1,PELP1,NCBP2,AATF,RNF20,CSNK1E,FXR2,RPS23,RPS5,DDX4,MTRES1,MIR198,WDR6,MIR424,GPBP1L1,PDCD4,TRMT10B,GTPBP2,RPS26,PHAX,MIR339,NKAP,RPS2,MRPS21,SCG3,MIR30A,ABCF1,MIR573,MIR551A,RPL3,DDX42,PPME1,SOX9,CSTB,MECP2,TPT1,RPLP0,TRMT6,MIR145,GDI2,SSBP1,EIF4E,ZNF207,MIR298,MRPS18A,PIWIL3,SF3B1,MIR1298,MIR17,RDM1,METTL14,PRR3,MIR136,MRPL18,MIR885,RNF40,ZCCHC17,MTDH,MIR132,MIR25,MIR186,MIR133B,TMSB4X,TEX19,NQO1,DDX1,SMAD1,APOBEC3A,MIR139,STXBP1,MIR152,GFM1,TXN,MIR920,DBR1,RPS17,EXOSC3,HSPA8,SLPI,MIR32,RARS1,CFAP20,SRSF7,THOC3,DDX23,MIR200A,MRPL20,RPL6,MIR29C,MIR130B,IREB2,MIR200C,YTHDF2,MIR135B,DDX50,POP7,CWC15,SMNDC1,CNOT6,CHCHD1,NOP16,RBM18,C1D,XPO1,DDX46,TUBA1B,HEXIM1,NOC4L,TLR8,MIR33B,MIR155,MIR373,IMP3,BRCA1,TRUB1,RPL7L1,XPO5,DKC1,SRSF2,MIR939,POLDIP3,CCAR1,MIR218-1,RPL26L1,MIR24-1,BST2,MIR193A,MIR188,CCDC47,NAA15,UPF3B,NUDT1,SNRPD3,NOL4,MIR448,MIR769,PRPF4,EIF2D,SRFBP1,SRP54,CNP,HSPE1,MIR301B,MIR204,RPL12,SOCS3,NOP53,HNRNPA1,MIR625,MEPCE,ISG20,EXOSC4,PPP5C,MIR195,LSM14A,ZBED4,MIR490,EIF4E2,HBP1,PEG10,ENO1,RPL10A,RBM17,PYM1,ERH,SRSF8,APOBEC3G,MIR101-1,DEK,RPL29,RPL10,KIF1C,MIR147A,EXOSC8,MIR10B,SART3,RPL17,RPL26,MIR511,MRPL40,EIF1B,ZMAT3,ARF1,MCAT,CDC5L,YTHDF1,TLR3,MIR301A,MRTO4,MIR342,APOBEC3H,CDC42EP4,RPL22,PDIA3,MRPS9,HNRNPC,HNRNPH2,MIR320A,EIF5A2,TFRC,SUGP1,APOBEC3D,SHMT1,APOBEC3F,GANAB,NGDN,ANXA7,RC3H2,SLU7,LSM14B,HSD17B10,SRPK2,MIR105-1,EIF2AK2,MIR1260B,RPL37A,SNRPB,MIR34A,UHMK1,EIF4A2,MRPS7,RAN,THOC2,RPN1,RPL18,ACAA2,MIR1277,RBM23,MIR30D,ATP5F1A,SF3B6,MAPRE1,AUH,YWHAG,KPNA2,MIR34B,ZC3H14,FCF1,EDF1,RBM41,CTU1,MIR548C,API5,MIR98,TOP1,FAU,MRPS26,MIR31,MIR454,RRP7A,DIS3L,CIRBP |
| 1.486e-26 | -59.47 | negative regulation of metabolic process | biological process | GO:0009892 | 3385 | 1256 | 18204 | 5365 |
PDCD4,ROCK1,MIR139,SERPINB11,STAU1,SUPT4H1,MIR143,ETV6,MAGOHB,PHAX,MIR15A,PIK3CA,SPOPL,CBX7,APEX1,EID1,HNRNPA2B1,MIR140,THY1,MIR939,PIK3CG,INSIG2,RNF41,FASLG,MIR572,SERPINI1,H1-3,MIR891B,KLF3,CCDC85B,ELK3,CTSA,IL23A,MTA2,VEGFA,MIR652,TIMP1,NF2,CEP85,MIR874,CCAR1,SATB1,NSMCE3,MIR137,IL15,MIR769,NUDT16,MIR298,MIR455,MIR194-2,EIF3E,MIR532,PPM1B,SOX14,H2AJ,MIR218-1,ELK4,NIBAN2,BEX3,CRYM,MIR493,RAN,MIR944,NR2E1,CUL3,NR0B1,MIR24-2,BSCL2,MIR301B,MIR922,MIR30E,YWHAZ,FOXP2,MAGED4B,TNRC6C,MAGEA4,LAMP3,ASB1,DUSP1,RASD1,CNOT6L,NIF3L1,MIR363,VSIR,MIR101-1,ATRAID,FBXW7,MIR616,POLDIP2,MAGEB1,NOG,MIR208B,PRR5L,HDAC6,SGF29,STK11,ALKBH4,APOBEC3C,MIR592,MALSU1,CCAR2,MIR129-2,CH25H,NR1I3,HNRNPL,ACVR1B,TMBIM6,BOLL,DCUN1D3,MIR16-1,PIH1D1,MAP2K6,NPPC,IGF2BP1,MIR7-1,DUSP6,H2AC25,MRTO4,PSMC5,PHF23,RBM42,POU1F1,DNAJC1,PDE2A,CIART,HCAR1,PIAS1,TBK1,XRCC5,ZBTB39,MIR632,FEZ1,PPIF,MIR32,ACOT13,VIP,C1D,APOBEC3A,MRPL13,MIR183,RPS13,G6PD,H2AC1,GCHFR,MIR373,USP38,TP53INP1,EIF4E,BAX,TRAF3IP2,MIR379,ZBTB2,IL6,ID4,PYDC2,MMP9,PAIP1,GNAQ,BAHD1,LSM5,SOX21,CHMP1A,MACIR,MAGEC2,NKX3-2,MIR223,ERLIN2,SPRY1,MIR130B,SNTA1,PRNP,MIR589,LMNB1,SMARCE1,MIR607,TENT4A,SLX1A,KLHL25,DAPK3,PPP2CB,COPS2,AKT3,HMX1,CD274,FOXP3,ERRFI1,MIR1224,OPTN,UCN,ANXA4,HP,MIR887,MIR454,MAD2L2,PAX6,ZBTB33,MIR423,MIR204,MIR577,TXNIP,WNT10B,NMI,FOXS1,NACC2,AQP11,SFN,DNAJB6,IFNA2,MIR96,CDC73,FABP4,MIR648,DNAJC3,PLCB1,ORMDL1,KCNIP3,HDAC3,MIRLET7D,MIR196B,SMG8,ZBTB16,ZNF24,MIR148A,PPP2R5A,E2F6,MIR580,RPL10,MCL1,MIR383,RBBP4,TNFAIP3,VDR,BAK1,TXN,MAX,GSTP1,MXI1,MT3,INPP5E,CCND3,MIR345,MIR877,IGF1,SAP30,MIR604,DKC1,PTRH2,CNOT2,SPRED1,PPP1R11,MIR331,MIR675,TCF23,CALR,SIRT7,MIR639,SKIC8,DUSP26,RADX,EXOSC8,TLR6,MIR211,MIR595,MIR374A,MIR182,ELAVL4,PPP3CA,CLP1,AKT1,MIR569,SIAH2,TGFB3,IL1B,CDK5RAP3,MIR450B,PRKCE,MIR448,MIR10B,E4F1,TCEAL1,PHC1,TSG101,MIR125A,NR1H2,ACP5,PCSK9,MIR187,CAAP1,PHF1,PAIP2,CCND1,HIRA,MIR130A,TRIM63,MSH6,PAK2,MIRLET7B,IL2,SOD1,HNRNPAB,UBE2D1,AR,CNR1,MIR492,RPL13A,MIR320A,TERC,MIR631,PFDN4,MIR1251,MET,PID1,MAP3K3,MIR1-1,LEPR,DDX5,NCBP2,PCGF6,ZC3H7A,SDCBP,HENMT1,MIR671,MDM2,MIR188,TP53,MIR583,MAEL,KLF4,ZBED3,IP6K1,PAX9,MIR147A,TGIF2LX,IFI6,APLNR,TLR4,ITGAV,CNOT8,MIR99B,PCGF2,TIMP4,UGT1A1,MIR26B,SAP18,PTPN1,BAG2,HSPA8,RPS26,MIR195,PIWIL1,IFRD2,LHX2,MIR198,MIR1249,DROSHA,ZNF692,LGALS3,RNF139,MIR335,ZNF668,MIR638,WDR6,CYP27B1,ZBTB14,APOC2,TRIM44,UFL1,RBM15B,SCFD1,MIR503,MIR212,SGTA,APOBEC3H,HELLS,NQO1,KLHL22,CDKN1B,IMPACT,MIR193B,SUV39H1,MIR218-2,HOMER3,SUFU,CDK8,ATP1A1,MIR191,MIR624,PDE12,PHB1,ING1,TWSG1,HMGA1,CAMK2N1,SHMT1,TNF,MIR9-2,MIR1298,CX3CL1,BRMS1L,NAB2,MUL1,XCL1,RBPJ,TBC1D24,KDM2A,MIR98,EMILIN1,ITGB8,HINFP,RNF5,MIR649,FBP1,MIR1296,PKIA,DUSP10,MIR628,ORMDL3,DNAJC10,HMG20A,BCL6,PFDN5,MIR615,HFE,HEXIM2,CDK5,BCKDK,EID2,PHF12,MIR338,NAB1,TYMS,RB1,MIR301A,CITED1,TENT5C,SUPT5H,RIOX2,LSM14A,TMEM39A,NDN,MIR105-1,MDFI,CDKN1A,SDR16C5,MIR16-2,CASC3,CLDN3,H1-5,FOXC2,PDCD1LG2,MIR552,PPM1D,ZHX3,GJA1,YWHAB,MIR502,H2AB1,MIR17,MIR214,NLRP3,PAIP2B,MIR764,TIMP3,MIR484,MIR761,RTRAF,MIR302B,FLCN,SFRP1,MAGEH1,FZR1,PPIA,CRYAB,AGO1,NUPR1,DUSP19,CST3,RORB,EPHA4,MIR200A,MIR605,RPS14,MOSPD1,MIR942,MIR3173,MIR7-2,CSF2,ETFBKMT,BTN2A2,BARX2,HEY2,IRF3,SRSF12,RNF34,PARD6A,MIR1225,KLF12,ID1,MIF,CCL3,HNF1B,MIR132,IL12A,LILRB1,SWAP70,MIR452,H1-10,LANCL2,MIR150,ING2,RUVBL2,DKK3,USP5,MIR876,CHID1,MIR101-2,TYROBP,CPTP,MIR661,MIR760,ZBTB17,FURIN,CD46,MIR149,IGFBP3,SCML1,ARPP19,MIR146A,NKRF,DGCR8,THAP1,BEND6,OPHN1,IL20RB,SOCS5,MYD88,NPTN,MIR504,IL4,SERPINB10,MIR662,RERE,TLE1,OTUD7B,LSM2,MIR9-1,DPEP1,MIR449B,MIR346,DUSP3,MIR370,RLIM,KLHL15,MIR192,LRP3,MIR597,STAT6,THAP7,ISG15,RNF8,CCR7,MIR1226,MBD3,HAND2,C9orf72,BHLHE40,DDX4,ZNF345,HCFC2,SRSF7,MIR517B,MIR30D,SPOCK1,DHX9,MIR600,DKK1,MIR25,MIR367,TOB2,SAP30L,MIR936,CCR1,MIR511,HDAC5,PRMT2,IRF8,MIR488,MIR558,CD200R1,MIR29C,FKBP1A,EIF4EBP2,TSN,MIR339,NR1I2,KDM1A,PELO,TRIM29,MIR489,BECN1,SNAI2,ZCCHC7,FIS1,DICER1,BANF1,IKZF5,CNOT6,IGBP1,DCAF5,DLG1,MIR215,DHRS7B,IL1R2,AZIN1,RGN,SUB1,MIR551B,GHRL,HNRNPA0,EXOSC4,CSNK2A1,CPEB1,MIR429,SOX9,RHEB,NDFIP1,CBL,HOXB8,PRKRA,MEF2A,MIR135B,LGR4,USP30,MIR34B,TENT2,BIRC5,ZBTB5,MIR873,DYNLL1,TAB2,MIR7-3,PLCL1,IFNG,HEXIM1,MIR148B,PHB2,ZNF175,NOVA1,CD200,TRIM21,MIR601,ATF4,POLR2G,HNRNPK,LEP,SQSTM1,MIR765,SRGN,NRDE2,MTMR2,MIR34C,ADRA1A,SRC,SMARCA5,PPID,SERPINH1,ANGPT1,PIWIL3,DRAP1,MIR549A,TFE3,EDC3,MIR29A,SRSF4,UBASH3B,EXOSC3,MIR542,LYPLA1,PRMT6,DNAJB4,SOX3,MIR181C,BMPR1A,MIRLET7I,MECP2,IVNS1ABP,NTRK3,MYT1L,TLR8,CIPC,IFI16,MIR296,NTRK2,TFIP11,MIR618,MIR563,MIR551A,CCDC3,CTNNBIP1,RGP1,NBN,TCEAL7,MIR153-1,EIF4EBP3,METTL14,MIR625,GTF2IRD1,MIR100,ITM2B,IRF1,BRMS1,TRIM3,INSM2,HNRNPD,TUSC2,TAF9,SERPINB1,MIR920,EIF4A3,PNRC1,IRF2BP1,ELOC,NR2F6,MAGEB10,SCML2,MIR24-1,SMAD3,DUSP22,NKX3-1,ATF3,NFKBIL1,FCGR2B,RPS7,MIR653,STAP1,STK38,CLU,MIR205,MIR23B,SETD5,MACROH2A2,MIR924,MIR599,KLF10,MINAR1,PCGF3,TESK1,ARG2,EIF2S1,NFKB1,MIR141,LRIF1,MIR491,TERT,SNAI3,PABPC1,MIR937,P3H1,IRF2BPL,HCLS1,PSPC1,PML,HINT2,SFTPD,H2AZ2,MIR378A,TRIB1,PLAGL1,CD2AP,CD38,MIR181D,MIR1180,NUDT12,GSKIP,MIR802,CAMK2N2,TRAF6,GADD45A,MIR222,ZBTB25,ERP29,USP2,MIR1-2,MIR633,SERPINA1,CSK,RFX5,ABHD6,MIR107,CAMLG,THRAP3,FOXP1,MIR190A,YWHAG,MIR185,PCBP4,LDB2,IL12B,MIR10A,MTA3,MIR449A,ZNF263,PPARA,SERPINA5,MIR186,JUN,MORC2,ENO1,LDLR,VDAC1,DMAP1,CBX3,MIR885,BAP1,MIR210,MIR129-1,MIR593,CD36,MIR33B,LIG3,SRSF10,RMI2,FOXD3,POU5F1,MIR197,TCF21,DXO,IREB2,LYAR,PC,SIN3A,IFI27,SERPINB9,RRAGB,MIR375,CPNE1,WDR82,MSX2,ANAPC2,MIR21,MIR30B,INHA,MIR519D,ABCC2,MIR651,FMC1,MIR548C,RTN4,MIR330,SYNCRIP,UBE2B,RGCC,TIA1,CTNNB1,CRTAP,SP2,MIR1227,SHLD1,BACH1,HYAL2,H2AC7,TSNAX,ANXA7,GPX1,EP300,MIR384,DR1,PDCD10,MAGOH,OVOL1,MIR99A,LSM4,PRMT5,RNF128,MIR92B,H2AC6,MIR9-3,SELENOS,GRB10,SMAD4,ZMYND11,LMNA,EID2B,MIR1271,GMNN,MIR578,SERPIND1,NOP53,MIR938,MIR136,CRY1,PPP1R8,GSK3A,DEFB114,DEDD,ABCE1,CD34,SMCHD1,MIR500A,PTEN,MCPH1,MAF1,BST2,MIR573,USP3,STAT1,PKIB,TIRAP,LRP6,PHF21A,CTDSP1,ARRDC3,MIR221,MIR155,PLAA,SLC8A1,MIR497,TRIM24,NCOA5,CRKL,MIR377,CREBZF,AATF,SNX12,LMO4,EIF2AK2,MIR206,MIR643,H2AC4,ZNF451,CYGB,MITF,VPS72,MIR770,MIR216A,FHIT,MIR34A,IL13,MIR609,UBE2D3,MIR133B,PFDN1,TAF7,CXCL8,RRAGA,SVBP,IDO1,TENT5D,FKBP8,ENC1,SMG9,MIR590,PTPN11,POLE3,NONO,DNAJC2,CDK6,MIR586,DDIT3,TRIM27,FGFR1,MIR340,ATXN1L,NKAP,HELT,PTPRQ,SIX5,PIWIL4,ADORA1,MIR155HG,YTHDF2,ESR2,MIRLET7G,MIR1262,EZH1,MIR554,CHRNA7,UPF3B,EZH2,SERPINA3,MIR28,CLN8,NR4A2,AP1AR,LSM6,RAD21,EPO,MIR934,MIR422A,EGR1,GAPDH,IKBKB,MKKS,CNOT7,CYP7A1,MIDEAS,PPARG,MIR626,PTGER4,MIR30A,RPL23,PAQR3,BTG2,TSPO,ZBTB6,UFD1,GABARAPL2,MIR193A,DCP2,MIR711,SLA2,GPNMB,MIR106A,SESN2,PGR,NMBR,CDKN2C,NKX6-2,TAGLN3,CBX5,MSX1,MIR145,CX3CR1,TRAF2,FOXP4,H1-1,ETF1,TRIM6,PPP1R1B,RPS3,MIR636,DDRGK1,ADIPOQ,RBBP7,LBH,MIR505,SRSF2,RAF1,ROCK2,IL10,MIR640,FERD3L,MIR611,H2AZ1,YAF2,MIR567,STN1,MIR875,GABPA,AGER,HRAS,PYCARD,MIR23A,MIR361,ZNF304,CORO1C,MIR495,HMGB1,DFFA,CXXC5,VPS28,EPHA2,RGS2,ZBTB45,SPINDOC,H2AX,FBXW11,CGAS,MIR424,DAP,ADNP,OGG1,PSMD10,INPPL1,APOBEC3B,CGGBP1,MIRLET7C,F2,MIR657,MIR581,MIR1277,ACOT8,TFDP2,DIS3L,XAF1,AZIN2,EIF4E2,STK38L,H1-6,LDB1,MYC,MIR184,IER3,MIR553,MIR126,CREB1,MIR556,DAPK1,HSPB1,MIR490,TDRD7,PRDX3,MIR142,APOBEC3G,FMO2,MIR106B,ITM2A,SPON1,MIR216B,HNRNPA1,DLX1,WWP2,HCRT,MIR557,SMAD5,SOCS4,EED,NFIL3,TGIF2,CDK5R1,CTDSP2,H2AC13,MAGED2,MIR105-2,APOBEC3D,MIR190B,CD83,INPP5K,CDK1,SNIP1,MOV10,APLN,RPS6KA4,MIR194-1,OSR2,VGLL4,CDKN2D,ERLIN1,FKBP1B,CBFB,HSP90AB1,AGAP2,CD28,BEND5,MEF2C,ZCCHC17,CAV3,MEPCE,RBBP8,SOCS3,TRIM11,IFNB1,PFDN6,CAV1,RBFOX2,SMG5,TNKS,USP8,RC3H2,ZGLP1,APOBEC3F,UBE2I,MIR324,SNRNP70,ZHX1,S100A11,ZBTB42,AP2A1,HBEGF,TNKS2,PSEN1,MTM1,ARB2A,LILRB4,PKIG,MIR208A,CNKSR3,CYP2D6,ZMPSTE24,RUNX1,ZMYM2,GFI1,WWP1,SNX3,SMAD2,MIR342,BRCA1,SERPINB6,MIR31,MIR612,PCNA,RING1,SEC22B,ZBTB38,SPRED2,MXD1,NCK1,SVIP,NOTCH2,DBNDD1,TGFB2,CHP1,CRYBA1,MIR144,ZNF177,DDIT4,TPPP,PIWIL2,MIR152,MTDH,CREBBP,PROX1,ZBTB18,GREM1,MIR147B,MIR940,GCLC,TRIM37,IRF2,SOX2,PTPN22,TM4SF20,FMO1,DYRK1A,HSBP1,ZNF174,CTBP1,SHC1,SUMO1,HNRNPC,TWIST2,OAS1,MIR425,ATP2B4,MIR200C,PFDN2,SMAD1,NLRP6,IRF7,MAD2L1,USP14,MIR1260B,XPO5,ZBTB26,MIR708,MACROH2A1,CSTA,CSTB,PYM1,PICALM,MAFG,MIR656,TRIM22,MIR20A,CIRBP,TADA3 |
| 2.402e-26 | -58.99 | FN1 (fibronectin 1) | protein interactions | 2335 | 830 | 373 | 19454 | 5460 |
RPL6,RAB5C,XPO1,YWHAG,NDUFV2,YWHAH,GSTO1,DDX1,RAB35,FUBP3,TTC9C,C1QTNF1,RPS10,HNRNPL,SNRPD3,CCT7,HSP90AB1,H1-3,RPS7,EEF2,TUBB4B,CCR1,RPS23,RPL31,ABCF1,EWSR1,MMP9,HNRNPF,PSMA2,VAMP8,RPS4X,MYC,HNRNPC,LDHB,HNRNPAB,SNRPB,CIRBP,CCT2,H2AZ2,RPS26,VEGFA,VDAC2,PRMT5,MRPL13,MATR3,TAGLN2,RPL10,PSMB3,DDX39B,RPS28,SF3B1,DDX5,PHB2,EEF1G,ITGAV,CXCL12,TPM3,GAPDH,RPL24,SMCHD1,MAP4,SSBP1,ALYREF,UBE2N,RAP1B,PLG,CAND1,CPNE1,MIF,ESD,KLK3,RPSA,CER1,CBX3,DISC1,SH3GLB1,GNAI3,DHX9,PSMA5,HNRNPK,CSE1L,RDH11,RPL17,PSMB2,SLC25A1,RPL7A,CFL1,ST13,IGF2BP1,SF3B6,CSNK2B,MACROH2A1,STAT5A,EIF4H,TAC1,DYRK1A,IGFBP3,PGK1,LSM12,RPS15,HMGA1,VPS26A,HNRNPA1,HNRNPD,PDAP1,RPL9,RPL8,PSMB5,MRTO4,KRT8,RPLP2,PPIA,DHX15,NAA15,LYPLA1,RAF1,RBM12,RPL29,PPP2R1A,ACTN4,ERLIN2,RPN1,PPID,BZW2,GDI2,RPS11,ITGB5,POLR2C,SNRPE,SLC25A5,HSPD1,ZYX,HNRNPA2B1,PCNA,BAG2,RPS27A,PRELP,FLOT1,RAB11A,F2,YWHAZ,RPS5,HSP90AA1,ILK,SNRPD1,SNRPD2,RPS9,SEC61B,PRDX2,TAB1,LGALS3,ACTB,TUBB,MAT2B,USP39,H2AC1,EMG1,SRI,SRM,PAFAH1B2,CLIC2,RPL12,PSMB1,CGAS,MRPS23,CCT5,NDUFA2,APOBEC3D,ACTR2,NDUFS3,C1QC,SERPINA1,TLR4,RPL23A,PTGES3,RPL26,AP2A1,COL1A2,MAPRE1,TUBA1B,ENO1,RPS12,MSN,ALB,COPE,UBB,UBE2L3,PDCD5,VIRMA,SEC22B,CCN3,METTL14,STOM,PICALM,HNRNPH3,WTAP,PRKCB,PPIH,PDHB,VPS28,SMAD9,DRG1,YWHAB,HSPB1,SRSF1,CORO1C,EIF2S1,TCP1,FASLG,RANBP1,SUPT5H,RPL18,CCT8,RBM3,PABPC1,RUVBL2,RTCB,PDIA6,RPL28,HNRNPDL,TMED5,ATP5F1B,FBXO22,RPL27A,PAFAH1B1,TSHR,SDC2,FDFT1,SNRPA,RFC4,XRCC5,HSPA8,HNRNPA0,KARS1,CSNK2A1,PSMG2,SMAD4,SNRNP70,RPS2,AGPAT1,RPL10A,USP15,SYNCRIP,EEF1B2,COMT,RPS16,TFRC,ARPC3,ACOT13,TAB2,PHC1,RPL3,KPNA2,CAPZA1,RSPH1,GSTK1,SUB1,TIA1,RPS17,LACRT,RPS3,PSMA6,MRPS28,BUB3,SPTBN1,AKR7A2,CAPN1,CFTR,NTPCR,H2BC11,RPA2,UBE2M,GSTP1,ACACA,HNRNPH2,PRDX6,LCP1,NAPG,HSPA5,MARS1,PRPF19,PRDX1,EIF3D,RAP2B,HBA1,PDCD10,RPL23,NQO1,DNM2,PHB1,XPO5,NOP58,ATXN10,MPP1,CCAR2,RPL7,CACYBP,FEN1,RPS24,G3BP1,LASP1,MCM6,ANP32B,MCM3,GALE,LMNB1,FAU,ARF1,RAN,EIF3K,AP2M1,RBBP4,RPL35,H1-5,PRDX3,APOBEC3C,MYL6,NDUFA5,HADHA,ARL6,ESYT1,SRP14,SEC23A,ARF6,G6PD,AKR1C1,YTHDF2,NECAP2,EEF1A1,RPL15,ILF2,HSD17B10,SNAP23,TF,HSPE1,RPS13,OLA1,EIF3E,CTSD,ATP5F1A,AR,NONO,TUFM,GMPS,LGALS8,NAPA,PELP1,EIF4A3,SMAP2,RTRAF,RPS20,LDHA,YES1,RPL13A,RPL22,DDAH2,DUSP10,RPS14,LMNA,MRPS34,CDK1,H2AC7,RPLP0,PRPF4,SIRT7,H2BC12,SQSTM1,MTDH,EGFL7,EIF5B,RPL4,HMGB1,NHP2 |
| 3.170e-26 | -58.71 | breast-carcinoma-ductal_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductal_carcinoma | 14824 | 4453 | 16828 | 4835 |
RASL11A,CLSTN3,TBC1D19,RGS6,CSTA,ELOVL6,ALOX5AP,TFPT,NUP35,ZNHIT1,MECP2,PRDX4,SLC25A14,SERPIND1,CHST7,ORAI2,CRYL1,RPL24,OLFM2,ENO1,GNPTG,PHF21A,COX5A,THNSL1,SLC1A2,RHBDL3,TRMT61A,CAMP,OMG,GPD2,CELA3B,FBXL7,LBR,CYP11B2,POP7,STYK1,DCAF4L2,RPRD1B,SNRPN,TSPO,LYPLA2,CHORDC1,ZBTB16,ANAPC16,OR5B3,BRMS1L,HCST,FBXO34,PAPOLA,DHRS1,IL12A,RHAG,TLR1,CAPG,OGDHL,CCR5,SAR1B,PTGES,ACADS,RNF128,PPP2R5A,VASH1,TLR7,GAPT,RALA,WDR55,FTHL17,F11R,G6PD,ADK,EXOC5,SYBU,SERPINB6,NAA15,PRDX6,AP2M1,TAX1BP1,KIN,TP53,NFKBIL1,CRELD1,INMT,PKIA,TRAFD1,TRIM35,PPM1B,STX7,SENP8,MGST2,GADD45B,HBA1,OSGIN2,LIMS2,GPC4,MZT2B,NECAP1,TSEN34,FTSJ3,GSTM3,SYNDIG1,PTRHD1,TOX,IRF8,RWDD4,KPNA6,CYB561,BET1,FCER1G,TMED4,HEXIM2,TBC1D17,HSD17B1,TXN,MAF1,RPS12,CYB5D2,ZBED3,DAG1,DUSP6,MTHFS,PPIF,SETD7,OR10A7,SERTAD3,MT3,EIF1B,PML,GABARAPL2,DNASE1L1,PSMA4,TAX1BP3,ZNF790,RDH12,TNFSF12,GABPB1,ARF4,TMBIM6,CCT8,PABPC1L,LSM2,DUSP22,SOD3,GFOD2,ADAMTS20,YWHAH,GABRB3,FAM187B,MRPL49,PLCL1,MTMR2,ICAM1,DNAJC7,CD83,RPL12,KCTD12,UQCRQ,ZNF177,ZNF652,HSD17B11,PPME1,C1QTNF1,AUH,TTC8,TFRC,ZNF267,IDE,TSPAN11,GGPS1,MND1,IPCEF1,HMGA1,OR1S1,FOXI3,UTP6,NTNG2,LRRC8D,VIP,ETFB,WNT10B,DGCR6L,FBXO11,RBBP9,SPSB1,SPINT2,BCL2A1,TMEM45B,AP2A1,APTX,HRH2,MIF,RBM15B,ZNF189,EEF1B2,C1D,TFDP2,ZNF22,ACTR3B,ATP6V1E2,ZHX3,IL7,SRSF4,NECAP2,SH3BGRL,EXOSC3,PID1,MYL12B,GINS3,ENHO,KCTD11,OPTN,GPR146,CLEC7A,APPBP2,ARPC2,CNTFR,KRT222,PDP2,NEURL2,SMNDC1,POLR2D,SNX12,FGF3,DRG1,ERLEC1,CEP85,SRPRB,NDP,TMEM42,SNX33,MED23,USP13,SDCBP,YIF1A,OR10Q1,CA8,RAB3A,DDIT4,SMYD3,KPNA2,FAM91A1,LCN12,CTNND1,NMBR,LGALS3,MAP4,LUC7L3,HHIP,FOXJ3,ORMDL3,RAD23B,USP30,TMEM60,CHN2,HBEGF,CALU,AIF1,HAX1,LRRC20,EGR2,OR1F1,RPS3,CUL3,COX16,OR5A2,PLSCR3,ARMCX3,TMPO,UBTD1,MAD2L2,COX6A2,POLR3GL,RBBP4,FAS,ATF1,ABCB9,CSNK1E,SKA1,GRB10,ELOVL4,PAK6,CHMP2B,RBP5,DNAJC4,ERVFRD-1,AKT3,MAN1A2,POLD4,CCDC92,LRRC4B,TOMM40,GREM1,COX4I1,FABP4,MPHOSPH6,ANAPC4,ARPP19,GDPD3,MRPL53,HDAC3,RPL29,GLRA2,MAP1S,BHLHE40,PI16,CARHSP1,TIMM8A,KLHL9,NPC1L1,TXNRD2,DNAJB4,AKAP17A,RAP1B,RAD21,SNX14,AIFM1,COQ10B,POLR2G,ACTR1A,LAT2,ACVR1B,FAH,CTDSP2,RPL10A,SDC2,IZUMO4,ALDH1A3,AHCYL1,ADM2,HNRNPH2,HMOX2,NPTX1,CLIC4,COX11,PAAF1,TFPI,PRKCA,KLHL26,BET1L,MMD,WRAP53,GAS2,UCHL3,TRAPPC4,EEF1A1,OR2AT4,TTC33,RPL39,BRD3,SURF6,FAR2,TMEM108,DVL2,TESK1,FKBP1A,SRXN1,DNAJC30,P2RY12,EHD3,ST3GAL4,MRPS18B,ZMAT2,DOLK,NT5C2,PHACTR1,SAMHD1,CRYM,TPH2,KCNS1,API5,RPL9,TST,DGCR8,RNF5,LAP3,ADIPOR2,C2CD2,EFHD1,EXTL2,RCCD1,ALPL,SLC20A1,PYGB,TRIM6,HOMER1,PSMB9,PDE8A,SLC4A10,FOXP1,SAMM50,KCNJ8,ENC1,OR5V1,PSMG3,GPR173,TOP2B,GEMIN8,RPS9,TIRAP,MYL6,SEC23A,TUSC2,SLC6A3,CASC3,CNKSR3,TCF21,CALML5,VAPB,PNMA1,SP2,HEBP2,TMEM50A,SMG8,MYC,LILRB4,CD40LG,FEM1A,CMTM6,VPS26A,EEF1E1,MKLN1,CCL28,RAB35,KCTD10,MAB21L1,PPP1R8,TNFAIP8L3,SLC48A1,CDC42,DUSP10,BACE1,SLC38A1,ACO2,VPS16,CLN8,SYK,SLC25A26,FTH1,SNX1,PSEN2,SLC35F1,CCM2,ALB,PIWIL3,IL2RG,PSMA6,PCSK9,KBTBD3,AKAP1,CLEC1A,DNAJC24,CPSF4,LCN8,AGA,CD63,AGR2,CACNB3,PCBD1,TTC23,NLGN1,TMEM174,MORF4L1,LAMP3,REEP6,MATR3,CHPF,CNOT6,S1PR4,TNFAIP1,TMEM11,PPP1R3C,CRADD,KCNAB1,AGTRAP,SEMA5A,APBB3,MCMBP,OR4S2,WDR82,TLR10,ZBTB25,CD28,NAB2,FXYD6,RNF11,CYTH2,SYNGR2,APOC4,TAF7,CRYAB,PPY,ROMO1,GNL1,ZNF473,SELL,KIAA1143,ATP1B3,DNAJC2,GNB1L,CCL27,ZC3H11A,TMX2,HTR1A,SFRP1,ELF1,WSCD1,GOSR2,SLCO1B3,FGF23,CYP2R1,SLC25A39,CD14,PRR5L,RANBP6,G6PC3,ZNF704,KBTBD6,UBE2H,FARSA,CD86,MANBAL,PNMA5,SLC2A8,PSENEN,OXCT1,ENO2,CFL1,KLHL3,BRIX1,IRGQ,DPM2,RNASE6,TP53I3,RNF40,RPS26,DDX1,KDELR2,DAP,FAM83C,UGT1A1,LTA,MRPS9,ABCG2,SPSB3,TOR1B,POLB,MNS1,POLA2,SEMG2,CCNH,KIAA0513,IFNB1,UBL5,BTN2A2,CSH1,TRMT112,SYNCRIP,SLC35F2,SLC16A10,DIO1,VGLL2,CLDN9,RNF148,PRICKLE2,MSTN,RPL27,PPP1R1A,PTH2,MTF1,SLC22A17,TNKS,ST8SIA5,CYP1A1,PLS3,BST2,PPP2R2C,SPON1,STK4,HINT3,SLC25A10,VRTN,GTF2H5,RPRD1A,DDX50,TEX264,SNRK,SERPINB1,UBLCP1,GSTA1,SRSF2,TRAK2,AVPR1B,ST7,KLF9,PIP4K2C,STUB1,NKIRAS2,FAM181B,ACVR1C,IL1R2,TMEM41A,SERPINC1,HLF,ACP5,TMEM59L,EGFL7,ATP6V1A,RFC3,SLC7A8,FBXO22,GPM6B,REG1B,PARL,DHRS13,GTDC1,UBIAD1,LRRC61,TSNAX,POLR2B,TRIM68,LRRC8B,ETF1,TAF10,FAM53B,PRDX1,NFKBIA,TUSC1,PREB,ATG7,RNF34,ACBD6,KLF4,DENND2D,COPS7B,OR10A6,OR4D2,SHOC2,HDHD3,DDRGK1,RPL32,PSMA1,CLCN6,AK3,HMGCS1,SLC25A12,HARBI1,TMED5,TCEAL1,PFDN2,LTB,USP16,GNPDA2,TMOD2,CRAT,NOTCH2,NAPA,PTPN11,SOBP,AVL9,DECR2,TP53INP1,IQCK,FAF1,VEGFA,CCR1,REN,SOD1,ASTN1,ATXN10,NCBP2,TBC1D13,SMPD2,DTWD1,UBP1,MAVS,KLHL22,CEP19,CHMP4C,PDAP1,SOX14,SLCO2B1,CX3CR1,IGF1R,FAM177A1,DCTD,SCNM1,MCM4,DROSHA,NR2E1,ORC6,FLOT1,THOC2,STARD4,BIRC2,MTM1,FCGR2B,IFIH1,POLR1B,CER1,CHCHD6,SIAH2,UPK1A,HOXC4,EPS8,RFXAP,SS18,MRPL22,CDCA7L,UMPS,CD1C,ZNF326,PLEKHO1,MYBL2,GSTM5,ERAS,CNOT2,OTOS,CRHBP,CLDN12,PKP4,GPR176,ELF5,CHKB,CCNY,FCGR1A,DNAJC19,VGLL4,SCML2,CLEC2B,SEPHS2,CBR3,JKAMP,ADD1,CLPB,VDAC1,FEN1,KLF1,ODAM,LANCL2,APOBEC3H,GLRX2,PRKACB,ASB7,SOSTDC1,ELOVL1,MORC2,SSR2,TPM3,SNRPB,EFNA3,PTPN4,GPX7,CHRNB2,RIT1,OR10P1,TMEM45A,CGB8,RNASE1,NLRP9,FAM43A,LAMP2,TMEM237,AR,IFI6,PPM1K,OR8B12,LLPH,GSTP1,CCL2,EP300,ADAMTS10,MRPL20,PEA15,RNF8,PLCB2,MAP2K1,APOBEC3F,HSD17B6,STAT5A,COPS5,MAGEH1,OTX2,EIF4A2,FEZ1,PRDM4,FPGT,LRRC3B,RCL1,SF3B5,PPAN,IL2RA,AQP2,SMAD1,CHST13,ZNRF1,KLHL24,GABPA,FKBP8,PPP2CB,PRSS12,PPP3R2,TIMP3,TMEM70,MPDU1,VAMP8,TTL,PMM2,PRMT6,USP3,CAPN1,CYP2C8,METTL22,ASZ1,TNFRSF1B,CDNF,TGFBR2,CEBPG,SPIN3,RPL23,CLLU1,CTTN,STOM,VAMP7,SEMA4C,SLC2A3,RABGGTB,FBXO7,LRRTM3,DAAM1,SCLT1,MRPL11,SH2D1A,PPP2R5E,UBB,SLC11A2,NPSR1,LMAN1,HSPA13,LSM10,LARP4B,PMP22,SERPINA1,STX11,OR2Y1,CCDC134,SLC30A7,TCF19,SLC6A6,GANAB,RPS6KA4,XCL1,BBS5,ZNF664,MLC1,MAT2B,OCRL,PDHB,DDX46,DHX15,OVOL1,RHEB,FBXL14,GPX1,TRIM15,RELL2,GRAP2,RAB27A,RPS7,NPPC,PSMD4,FASTKD5,CST11,SNX22,SFXN2,TMEM117,NDUFB6,MRPL34,CYP21A2,GNAO1,NCDN,UBL3,IMP3,IRAK4,GNPDA1,COMMD6,KCNJ3,B3GALT1,TMEM30A,AFAP1L2,ST6GAL1,HENMT1,CSTF3,RPL7L1,BFAR,TOMM22,UBA3,CBLL1,TOR3A,GLRX,PRR3,IL22,EPCAM,PCDH17,TAGLN3,SAV1,STAT2,SRSF7,DKK1,HERC4,NR2F6,ASNSD1,CNTN2,ZMYM3,CRIP1,PSMB1,BAG3,ZNF365,ORC5,ILF2,OXSR1,RBM22,RRM1,KRAS,RPS16,KDELR1,TOM1L1,OLFM3,SCG3,BMPR2,COMMD3,PPP1R1B,RND2,SCGB1D1,ILDR1,NLRP3,CCS,RASD1,IER2,CHPF2,NDUFAF3,SLC16A1,OR13C8,TMEM101,NUF2,HINT2,ELOVL7,DBT,RAPGEF5,TPD52,DSTN,DAPK3,RPS27A,PCDHB13,PSORS1C2,POP5,CHAC2,G3BP1,MRPL18,FGFBP1,MFSD5,SLC38A7,PGGT1B,OXTR,KCNC1,LAPTM4A,FBXL19,MRGPRX3,SUFU,CCDC86,MTA2,CHIC2,CHCHD4,METAP2,MME,SEC22C,CTXN1,MAPRE1,NRN1,MUL1,SMG9,GNG10,ARG2,DNAJB9,RNF144B,GLRX5,RTN4,GNAZ,SIAE,ISX,GAMT,FKRP,OR10A4,USP15,ELMOD2,PABPC1,GNG12,NTRK2,APOBEC3G,CRLF3,UCN,INO80E,DEPDC1B,RLIM,PTEN,UAP1,THAP7,MGAT5B,CLDN3,ADAM21,MOXD1,CCDC160,RPA3,SIT1,FDFT1,NEGR1,RORB,CKS2,CXCL13,ABHD5,EPHX1,RWDD3,TXNDC12,GFPT1,SDHB,SNRNP48,ATG4C,FRRS1,CENPW,BCL7C,IL1A,THBD,OR4D6,CNDP2,PPFIA2,CINP,FBXW11,PGRMC1,METTL15,NEUROD2,TMEM147,USP8,COX8A,LGALS8,DHX38,GPR171,PTK7,JAGN1,SNAP29,NDUFAB1,HTRA2,RPL27A,NUDT12,CBLN2,TYW5,PDE1B,PIK3R2,DDX23,PCNA,SPRED2,OPRM1,CDAN1,CTSC,NDUFS6,TMEM126B,NXT2,FZD3,CD247,RHOBTB1,IKZF5,CHST2,FBXO44,DKC1,ARPC3,HR,LRRC3,DNTTIP1,AGPAT5,PLD3,PCYOX1L,CREG2,OPHN1,SUMO3,ZNF687,OGG1,CCR3,RAB23,CMAS,PTGER1,RHOJ,CBLN4,WWP1,TMEM50B,JUN,IFNG,CD47,HIRA,S100A8,SPTBN1,GNPNAT1,GIMAP2,TOMM40L,UTP23,CHI3L1,RNASEL,PPDPF,TNFSF18,DNAJC8,RAB33A,CRYGD,RNF167,FAM107A,EGLN3,DYRK2,FOS,OAT,MRPS28,RIOK2,POMP,OS9,RPL26,NFKB1,PRKAG1,PAFAH1B3,HNRNPK,LHFPL2,ACAP2,SCD5,MAFG,TAPBP,GGCT,RCBTB1,ATP6V1C1,OR2A25,STX6,FANCG,PLA2G15,TPPP,RFTN2,SLC35E1,CAPZA2,RB1CC1,NAA60,CCL8,YPEL5,PPID,HSPA14,CXCR4,NPY5R,CDH13,POLR3B,BRD9,LCN9,PGR,HAND2,KCNH1,CCL17,KIAA1191,GTF2F2,PAFAH1B2,OR2H2,BICD2,CREB1,SERPINA5,KIAA0408,RNF122,RAN,RPP25,RBM12,GLIPR1,SQSTM1,TMEM177,FMO2,CLDN8,CXCL14,ADAMTS1,TUSC3,RPL6,SPRR1B,BNIP3L,DDX42,SLC7A14,GMPPA,CYB561D2,MT2A,PPP1R16A,PXMP2,ATP1A2,RABL3,UPF3B,ISCA2,ZNF576,GCA,PPP1CB,TRAM2,MPV17,CHST1,EHD1,RFXANK,TRAM1L1,PAPOLB,PLAGL1,SESN2,KLHL15,CRYBB3,OR4F6,TAS2R5,ACTR2,SYNJ2BP,ACP6,TMEM164,APLN,ZNF609,TMCC2,KCNK10,SLCO1A2,SRP14,NUS1,TMEM106C,PLEKHA8,KRT7,MANSC1,GJB2,WDR3,ELSPBP1,STX18,ORAI3,SLITRK2,RBFOX2,FOXN2,CDKN1A,GK2,PPFIA3,OTUD7B,SDHAF2,MED11,CLIC2,SOS2,PIWIL2,PGM2L1,ROGDI,SLC23A2,GYS1,ACTL6B,LY6G5C,UBE2D1,SNIP1,SLC4A8,ABHD13,ZBTB45,HRH3,RAB1B,INHA,RPAP2,RGS5,OR5L1,RBMX2,NDE1,AMY2B,LDHAL6B,CCDC65,HMBS,TDRD7,CD2BP2,MRGPRX2,LRRC24,GRIA2,LIX1,KLK5,CAB39,DDX4,ZCCHC9,SLC43A2,TOP3B,TEX12,HIGD2A,TAF5L,PNPLA8,MYEF2,GLT8D1,NGB,UQCR11,MOV10,PCGF3,GPX5,TCEAL7,TMEM14A,CDH8,CPSF2,BEND5,CMPK1,SNRPA,CTNNA1,RAB2A,WDR44,TRAPPC6B,CCNF,VAMP2,CRBN,CD226,VPS33A,SACM1L,B4GALT3,PDYN,ZFP1,KCNIP3,INPP4A,ARCN1,EZH2,RAB9B,AMT,FN3KRP,WIF1,DYRK1B,PHYHIP,STAT6,OR10G7,ACADSB,SNX24,ISG15,EIF4B,SLC25A4,MRTO4,PTHLH,SMAD3,PPP2R1A,PLEKHJ1,MLF2,TIMP1,DERL2,TXNL1,IL6ST,TMEM59,RPL23A,LYNX1,RAB37,SLC6A11,FOLR1,CAV2,IFI35,FBXO25,PSRC1,CSTF2T,C1QL1,STK38,TIMM10,AP1AR,SMN1,PCDH19,RAB5C,PNP,WEE2,EMP3,OSTM1,CHMP2A,VMP1,CBR4,SLC19A2,HSPA8,GMPPB,CALHM2,CCDC25,TES,BECN1,LMNB1,EED,MRPS16,ABHD14B,YAF2,ELP3,TGFB3,MRFAP1L1,ACSL4,TRIM24,CIB2,MTRF1,ZNF592,EWSR1,PROS1,GPX3,TMEM204,SNAPC3,BLOC1S2,SNCG,AKAP12,IGBP1,SSU72,DDX39A,RAB40AL,TMSB4X,EIF4E,TRIM5,CALHM3,LHFPL4,COX4I2,CDKN2C,SPECC1L,KHDC1,NAT2,RINT1,BZW2,TSPAN5,OR10G9,ZBTB17,BCAP29,FABP7,CD274,CREB3L4,B3GALNT1,EIF3K,FUT9,PHYH,RTKN,NTN4,RPLP0,UBE2V2,IL10,RNF113A,EFNB1,THTPA,PREPL,SH3GLB1,TSPO2,OLFML3,GOLGA7B,CSNK1A1,ITGA6,COMMD8,TFE3,IFNA10,DEFB114,MT1M,IRF3,CD36,MTHFD2L,KLC2,PAX9,STXBP1,PCMTD2,STOX2,PRKAB1,UQCRH,DPEP1,DERL1,IL18,CSNK1A1L,SOX2,ST3GAL1,SLC32A1,PARP11,ZNF501,IFRD2,ST3GAL5,POR,STK24,LCA5,RAC2,LRP6,PYROXD2,MRPS21,CDK4,NPR2,NR1I2,CNNM4,BRCA1,ABHD4,PCDHB1,TRAF2,RBM7,KCNK13,PDHA1,ADPRH,MBD5,BCL10,NOS1AP,KCNMA1,RGS2,STMN2,NME1,DUSP19,RNASEH1,DNAJC3,TMED7,KLK6,FKTN,SERINC3,SLC41A3,STAU1,TSN,STOML3,TRIM54,ACBD7,FAM98A,CDC42SE2,RPLP2,TGIF2,GREM2,POPDC2,GPX6,OR4Q3,HTR1F,GPAM,PDCD4,LDOC1,PRPF19,CREBBP,RDH10,RUVBL1,SDF2L1,CXCL3,GTF2B,NKIRAS1,OAS1,GIT2,CLDN4,LAMB2,SLC13A5,RAB3D,ZNF287,KDM4B,ACAT1,EDEM1,GNG2,METTL14,VAMP5,MBL2,MAP3K11,GTF2H2,PTS,TOR2A,JPH4,AMIGO1,COL1A2,RMI2,SMU1,SLC35D1,SAT1,TFCP2,CLDN1,ABHD6,METTL2A,CTDSP1,CCNB1,FAM162A,AKAP14,CRYBB2,NDUFAF4,ERH,ALKBH5,ADIPOQ,ANKRA2,IK,CRTAP,LCP2,UHMK1,GPHN,ISG20L2,HSP90AB1,POLE4,SYP,ATG4A,CSRNP1,MRPS23,FUNDC2,RER1,FCN2,CDKN2AIP,SFRP4,DSTYK,ZC3H7A,AIF1L,CCR2,ZBTB5,TMEM123,CIDEB,ARMC7,ATAT1,IPO8,TMSB10,F9,PGPEP1,NKX3-1,GCNT3,OPRK1,MYO6,NDUFS8,CYP2C18,SNX17,BCS1L,APOO,TMEM144,TOP1,NRSN2,HTR5A,TMX3,DNAJC22,EIF2B3,CHGA,GBE1,PAPSS2,TCF23,GPR65,SEC61B,TOM1,BCL7B,LTBR,OR4D11,GAL3ST1,CASK,FGFR1OP2,GABARAP,PRPSAP1,ELMO1,TCP11L2,GRPEL1,CCT2,UBE2D3,ATP6V0E1,UBE2A,ARMCX1,OR8B8,IRF1,P2RY1,STRBP,ING1,TRIM23,NHP2,SLAMF9,ZMYND19,TAAR1,CCR6,ID4,ZNF319,SEC14L1,APOBEC3A,ZNF397,XAGE5,GLUL,CNIH4,CDK5R1,NCKAP1,NRP1,ATPAF2,KIAA0232,CLU,LMO4,CYP39A1,HSD11B1,MYL12A,LRRC69,SWAP70,FAM8A1,EIF4H,ITK,NCR3,CHDH,GNRH2,SENP5,IDH3B,CYP11B1,PYDC2,CTNNBL1,GRM2,TLR3,GPAA1,JAKMIP1,OSM,IL15RA,SLC38A9,RMND1,MIOS,FAM78A,PPP1R2,ENY2,RAG1,IMMP2L,DHRS4,SLC35A1,MRPL24,MRPL50,ZNF304,SLC30A5,KLK3,LYAR,TOM1L2,EXOC8,PFDN5,UST,RND3,CNP,NUDT3,SPRN,GSTO1,TMEM156,GALNT1,SOCS5,AK2,PSMA3,CCDC69,MRPL13,EHBP1,MDM2,MGP,L1CAM,TLR9,COMTD1,FNDC8,APEH,FGD2,DLX1,AKT1,CRABP2,PRRC2A,RPS23,DPP10,SF3B4,IL20RB,DKK3,CCNI,ASMT,RAB11A,PPIL4,CDO1,SLC17A5,ZNF671,SLC25A31,UGCG,MEAF6,LYPLA1,RPS14,LIG3,ATP6V0B,TMEM219,EDF1,ZNF207,POLR3H,C1QC,TRIM3,TMUB1,E2F6,ZMPSTE24,EXOSC1,GPR89A,MRPL23,GDI2,GFM2,KLHDC8B,RNF141,ARHGAP1,DOK4,PLA2G5,KLK9,SDR42E1,UBR7,PDIA6,CD99L2,SNRNP27,PRIM2,TRIM32,HCRT,FGFR1,SHC1,PYGM,OR4K1,PEX3,FAM89B,RCVRN,KCNJ11,PPP3CA,CRYGB,CD200R1,CIB3,TACR3,PRMT2,CAMK2G,SRP54,BUD31,TMX4,CCDC47,TTC4,SCFD1,GHITM,TUBG1,RPL15,ZNF593,ARMCX5,PRPF4,IMPACT,CD58,AGER,IDH2,FKBP14,RAB18,CCT5,ENPP4,MCOLN1,PSMB5,SORD,SLC39A7,AGK,FBXO32,ANAPC2,ACTA2,TRIM21,SIX5,ARMCX2,SPR,ARFIP1,GALNT12,PPARG,NFIL3,TRIM37,HECW1,PTPN1,HNRNPC,RMND5B,RBBP7,SLC25A21,PGS1,FAM199X,PAEP,NIPA2,RABL2B,CLDN11,TRAPPC1,SLC35E3,SPTAN1,RNASET2,NPY2R,LRP12,ZDHHC14,ADRB1,PKNOX1,FRMD8,RFX4,HEY2,PCDHB8,RBM17,FBXO42,TMEM215,ZNF24,TSEN54,SERPINB10,FZD4,MEST,WDR77,MTPN,ATP6V1G1,LYG2,MFSD6L,GPBP1L1,MX2,SYN3,ZCCHC10,AAMP,NDST1,TNFAIP8L2,DEFB116,DHRS3,CDCA3,RAB3B,KTI12,FGF1,ABCB1,AZGP1,HBE1,INO80C,PSME2,AZIN1,CCL19,TBC1D10C,MAGOH,GTF2E2,MLF1,LBH,JAK1,JOSD1,P4HA2,SUPT7L,RS1,KIT,LSM3,OR4D9,GRSF1,RARRES2,KPNA1,CSNK2A1,PIWIL4,GSTO2,KBTBD2,ATF4,CTNNBIP1,GNG7,SNAP91,MYH2,HEBP1,ALKBH4,SLC7A9,PACSIN3,PGK1,ROPN1B,VRK1,TMIGD1,DNAJC5,S100A6,DYNC1I2,CYP27A1,ZYX,UBAP1,CDC73,LHX2,MMP9,BTF3,MSX2,CDC37L1,SNAI3,PELI3,KRR1,NLE1,ISYNA1,NDUFB8,APH1A,CXCL1,FRA10AC1,PDIA3,XPOT,WNT7A,LEPR,STX17,HADHA,LEAP2,DHX16,SOX21,RAB4A,TRA2B,OR6M1,NUDT16,B4GALT6,HSPB1,KCNA2,LHFPL1,HSPE1,CLDN14,ZKSCAN1,STAMBPL1,SIPA1L1,PGBD2,SERPINH1,RPL37A,OXNAD1,RBM23,TMED1,ADAT1,OCEL1,HEXA,BRI3,CHRNA7,KIF1C,GAS8,CDKL2,CD3G,BRMS1,PAOX,IPP,NQO1,TBCE,SPATA2L,NPVF,LMBR1L,IGFBP4,AKR1C2,TAC1,OPA3,ST13,RASGRP2,LPXN,DFFA,IL34,RAP1A,UCKL1,ACAA2,RABAC1,WWP2,FBXO30,TIGD7,CD2,POLR2I,PTCRA,NEDD8,CXCR1,HBB,FGF17,KCND2,CCL21,NDUFA5,RANGRF,ABCC5,THOC1,DNAL4,FATE1,ATP2C1,RC3H2,PFDN6,LDHA,NUBP2,UBXN10,PCDHA5,SLC20A2,GSK3A,GPR162,APOBEC3C,ZMYND11,SLC7A4,ZNF513,THRAP3,EEF2,GJA10,EFHC1,SLC25A32,XPO1,EXOC2,XPO5,SURF4,INTS10,TF,RNF103,CREB3,UTS2R,NEK7,PHKG1,LASP1,SPOCK1,FUT8,WBP2,GTF2A1,EIF2B5,SH3GLB2,GALE,CXXC5,CIRBP,ANKIB1,ZSCAN1,OR51S1,EIF4EBP3,WDR37,IL23A,PSMD6,SLC39A9,FURIN,DHX9,TXNIP,CREBL2,AQP4,CCL25,GNMT,ANP32B,CHST9,CPT2,DCAF8L2,NDNF,AP1G2,PWP2,RAB3C,MTAP,CTSK,CACYBP,CETN3,URM1,NFYA,S100A10,FAM200A,STX8,TGFB1I1,DUSP1,TOLLIP,BATF,AP3S2,MRPL47,TMEM33,S100PBP,MPHOSPH10,KLF10,BMPR1A,FAF2,RHCG,SPINK13,ARHGAP21,LCN6,SETD4,RPGRIP1L,OR2W1,CCND1,WFDC13,TMED3,ACOT13,FBXO9,COX7A1,CCDC42,FCAR,NPTN,POU1F1,CYC1,PTDSS1,ID1,ARMC8,SLC35A2,ENTPD4,DEGS1,CRYBA2,INPPL1,KIF2A,MIA2,BACH1,AKR1A1,NOP58,NFE2L1,RBCK1,MRPS25,CTSD,PGAP2,MRGPRX4,FABP5,OR52M1,NUP107,SCAMP2,SPEF1,SLC5A6,PRKD3,CYP4F8,NLGN2,DEK,PPIB,BPGM,CDKN3,CD164,SIRT7,FYTTD1,NOL4,IQSEC1,TAPBPL,ETV6,RRAGA,RAP2B,ABHD16B,TNFAIP3,MMACHC,TRAF7,DUOXA2,MTMR12,SOST,TCP11L1,SV2B,HPCA,OR2A2,EIF4EBP2,GFOD1,SIVA1,SNTA1,SNAPC1,GPR37L1,NDUFAF2,SPRED1,TSSC4,ALDH1L1,POLL,NONO,SLPI,USP39,CERK,ZNF174,USP38,SYNGR1,RTP4,LSM6,PRKX,FGF13,PROX1,ENPEP,NAB1,SFTPD,CLEC12B,RAB8B,CTNNB1,CYP2D6,SOCS2,DCAF5,ESR2,CDK6,CWF19L1,SNRPD2,ADCY3,ZC3H14,CBFB,EFNA5,ASPM,ZC4H2,TADA1,CETN2,SMARCE1,PITHD1,SH3BP4,LEP,RIT2,IFNA13,CACNG3,OR4B1,PDE6D,OR5K1,PDZK1IP1,S100B,TNIK,LRFN3,UBE3A,MRPL12,FGR,RCHY1,SPHK2,B3GALT2,PPT1,ARF6,DOK5,DCTN4,SEC22A,MAP2K3,CXXC1,RPL7A,FIG4,LSM12,LAMTOR2,SLC41A1,PNRC1,UBE2I,TMEM106B,UCP2,MXD1,MFAP1,MAP3K3,ARL11,FHIT,ARGLU1,EZH1,RNF7,TECR,MRPL16,DICER1,SLC6A7,MAGEB1,IL21,RPL19,MSN,POU5F1,HBM,FGF16,ZNF362,SLITRK5,DDIT4L,SAP30,RNASE4,GLIPR2,SPCS1,TDP1,MID1IP1,SNRNP70,SERINC1,PLEKHF2,SMUG1,CDH7,ASCC1,SLC37A4,ZNF770,TPD52L1,DUSP18,LYRM2,FBLN5,FOXD3,MAEA,EID2,ZNF345,KIAA1958,CXCL10,COX7B,CDC42SE1,BGLAP,RGS1,SDHC,ASB11,FAM83A,RHOG,NOL12,SEC61A1,TTR,GAD2,METTL18,RSBN1L,PHF7,MRPS26,HMGB1,TUBA1B,CKB,THAP6,ARF1,ZMYM6,EIF2B2,GNG11,BTBD10,ZBTB26,LRRC14,EMILIN1,PDCD5,PRDX3,ZCCHC7,PPIL3,CTSA,DPAGT1,LPCAT3,GPR83,SERTAD1,KCNIP2,ZHX1,HNMT,FA2H,ERRFI1,GJB1,GCHFR,PCYT1B,CSF2,PRELP,KRT8,CHCHD2,SKP1,IZUMO2,TPST1,ZNF200,LCP1,AGGF1,HDAC11,SIGLEC5,ATG16L1,DIRAS3,TP53TG5,TTLL10,RPL4,RGL1,SUV39H1,DYNLRB2,CKS1B,SPAG11B,HBP1,SLC25A3,RWDD1,COPE,RBM41,DCTN3,LSM5,IRF2BPL,PRKCB,PABPC5,HCFC2,OR4M1,BMPR1B,HS3ST1,TULP3,PSMD1,BARX2,MPP1,SRM,RANBP10,ADH1B,BLVRA,RAB32,PITPNA,CRYBA4,CRYZ,FOXC2,PCBP4,MLH3,APOBEC3B,CDKN2D,GPR37,ESD,ATP6V1D,VWF,PSMB10,CDK17,ART5,TMEM39A,VPS39,MYLIP,FAM174A,SUPT4H1,SART3,IFI16,PTPRZ1,CLP1,CLPX,OR5AN1,ATG3,INA,CFTR,HINT1,TNPO2,THOC6,CCL11,RAB9A,RXFP2,MARCKSL1,SLA2,IFNAR1,SDR16C5,SPATA4,CMTM7,TBC1D16,CA12,SLC7A1,ADRB3,FMOD,RAB11B,STX5,ARL6,CCND3,CSRP1,IRF4,LEMD3,LYPLAL1,HSDL2,OPRL1,NUP62,RNF139,SMG5,PLP2,ABCF1,DUS4L,DYNLL1,SRP72,SLITRK1,DDIT3,RPL28,CACNB2,HCFC1R1,FIS1,EDEM2,PIGC,ARFGAP1,MVD,STK38L,CYP4F22,PREP,CDC26,SHC3,CCL24,SNRPD1,JUNB,ALCAM,PTPN5,RNF182,TIMM17A,SMAD9,LIPA,SLC39A10,MCCD1,TCEA1,BCAS4,HM13,PGAP3,VCPIP1,DIS3L,CA14,CEP57L1,OSBPL8,TACR1,ARHGAP19,NACC2,CHRM5,DRD3,EMILIN3,CEACAM5,NAP1L3,TIMM13,XBP1,RPF2,TBC1D1,GPR34,THG1L,PDLIM4,GABBR1,ERCC3,MRGPRX1,HPCAL1,NAP1L5,SEMA7A,TRMT5,OR9I1,BCKDK,ZCRB1,MED4,CYB5B,APOC2,NPBWR1,RPSA,PIK3CG,ARHGAP15,RHOH,ERLIN2,HYAL2,UBE2S,RRP7A,RBM3,CORO1C,RACGAP1,MAGEA4,STT3A,ZNF343,EGR1,WBP11,ZNF436,CHTOP,SYPL1,SETD3,GPR75,TMEM126A,ACTL6A,ACP2,FOSL2,GNPAT,TCTA,PCP2,ADD2,SOD2,SCN2B,TEF,ANKRD10,NEU1,VSTM4,AMELX,PDCD1LG2,GLO1,RAB1A,FBXO31,MAP1B,CNOT8,PIGK,PELI1,MLN,KLF12,WDR12,SOX9,CHST10,KCNG3,GAB1,JMJD8,ITPRIPL2,AKT2,PRSS1,APEX1,PSMC5,TLR5,LCN1,RFC4,HS3ST3A1,TICAM1,GPM6A,PNPO,OR2D3,COTL1,ETFA,PRELID1,AQP3,ECD,CD59,ACTR1B,HTR2A,SMARCB1,ALG5,DEXI,SUGP1,FMO1,STARD5,ABCC2,DCAF16,GTF3C4,MMP20,C1QL2,PLCXD3,REG1A,DNM2,OR4K13,HAS3,PRPS1,OLA1,TSPAN3,BAD,MGST3,UQCRC1,NOC4L,CRHR1,PDCD10,GDAP1L1,SSBP2,LRRN4CL,RPL31,WTAP,NETO1,CDR2,PTGER2,C9orf72,NAA30,PSMB4,HERC3,SEMA3C,DOK6,LSM4,HSD17B8,DDX39B,CGRRF1,TRAF1,RSL24D1,CLK1,SKAP2,RASSF4,KCTD20,SERPINA3,ZMAT3,BRS3,PLEKHF1,ZBTB6,AHSA1,KCTD16,SLC15A1,TRIM62,TEX19,ZNF655,GPR78,ST8SIA4,TMEM220,TMEM168,CD200,SIAH1,STRADB,LRP3,NCK1,SCG5,PHOSPHO2,OR6C4,RFX5,TRAPPC2L,MAT2A,NMRAL1,COX7B2,CDKN1B,TAF9,MEA1,HMGN4,SCHIP1,GFM1,SSH3,HOXB8,CENPM,SEC61G,EMX2,POPDC3,SLC7A11,MET,FZD6,ADIPOR1,PRM1,GAL3ST4,TIMMDC1,SERPINB9,MT1X,UBE2V1,SNX11,RPLP1,PDE6A,IMP4,TRNP1,HELT,B3GALT4,DLG3,RHOU,TMEM176B,CEBPE,RPL22,ATF3,CTLA4,RBM5,RANBP1,ACSS2,IFRD1,DEFB1,MAP1LC3B,PRSS37,PDLIM3,LDB1,TRAPPC3,CSRNP3,NRGN,GMDS,WNT2,BIRC5,ANKH,VPS26B,YKT6,CAMKV,ESYT1,F2,ARL5B,SAP30BP,HAPLN2,EDC3,AANAT,FKBP2,PRSS35,TBCEL,CYP26A1,GMNN,NUDT1,RALB,ISG20,TMEM87A,DTL,ABHD2,ARL6IP5,CTDSPL2,SNN,SNRPA1,CCDC22,KDM1A,NDFIP1,SAP18,EXOC3,CAP2,SLC22A6,SPG21,TIA1,DDR1,HSPD1,EIF1AX,RNASEH2C,PNPLA4,PIAS1,NPC2,TMEM115,PARD6A,LRRC28,TCEA2,TMEM183A,BTG3,OR1M1,RUSC2,CD9,GRPR,IGFBP3,GADD45A,RBMS2,TGFB2,VPS54,SLC25A27,ATG9A,ZNF622,S100A11,GLOD4,PIGA,BOLL,MX1,TRIM44,NR1I3,LRP10,CCDC3,VAV2,BTG2,ITGB8,TMEM229B,HINFP,NUFIP2,GNB3,CRYBA1,MPV17L2,THAP8,WDR45,NRM,HSPA5,GNA11,SERTAD2,HSPB6,TICAM2,FAM20B,FHL3,PPWD1,PQBP1,GPRASP2,P2RY4,FBXW4,ST3GAL2,TAS2R7,CD209,IL2RB,PTGFR,IP6K1,SLC25A24,GLCE,SSNA1,GK5,STAR,TRIP4,RPL10,PDCL,SUPT5H,APLNR,CYP4V2,NCAPG2,SRI,DTWD2,PSMD3,POLR1D,GPR160,RNF10,GP9,OR51E2,POLE3,KRTAP8-1,ZDHHC16,OR4D5,TEX261,PPP1R11,MDFI,MSH6,RAP2A,TNFSF15,SLC6A2,CD40,AIP,CRY1,ARFGEF1,NOG,TLR8,PMPCA,PYCR2,PDE2A,ZNF428,TNFSF8,CDIPT,SIN3A,CDK7,PLAC1,SCAND1,PSMD7,CTTNBP2,RAB6A,RGN,FKBPL,DCTPP1,TMEM100,OR4A47,THAP1,CD34,FBXL4,CPXM1,PRCP,EID2B,PIWIL1,TRAF3IP3,CCDC90B,SRPK2,TAB2,LDB2,YPEL4,RNASE9,GADD45G,RPA2,TMEM107,SRFBP1,PFKFB2,ARHGAP12,EIF5B,ACER3,MREG,DIRAS2,YTHDF2,FAM161A,ANKRD6,FKBP1B,LMO2,EDA2R,LCORL,OR13A1,PSEN1,MAGEC2,RASSF8,CLEC6A,SSBP4,RBP2,AQP11,ZNF581,DUSP3,PDE7A,SUCLG2,CIAO1,ATP8A1,KIF3C,GHRL,VPS18,NAA16,GJC1,RPS20,SLC12A2,RUNX1,SCML1,ZFAND6,TAPT1,TYMS,MED10,SPRY1,RPS10,CLDND1,CCDC106,TBCCD1,TRAF6,VPS72,KRIT1,ROCK2,KCND3,GIN1,TKTL1,RPL18,MGMT,TRAPPC6A,MDC1,ITM2B,MTCH2,CCSER2,SP1,IMPA2,TADA3,TRAM1,AP1M1,FUNDC1,ECHDC1,UBA52,TMEM165,OR8B4,KLHL25,RPE,SULT1B1,SLU7,PTP4A2,FAM3C,MFAP3L,IRF7,PRR13,SLC25A5,OAZ1,WSB1,TOPORS,LYZ,ADCK1,CYBRD1,FAM151B,FAM136A,SLC35E4,SGIP1,MRPS17,MECR,MRPL9,UBE2G2,FEM1B,FXN,UPRT,SUPT3H,KLRC2,TOX4,TMBIM1,CYTH4,CPNE2,IFT172,RAMP3,NUCKS1,IER3,TRIM26,CENPL,RRAGB,SNRPE,GRIK1,CMA1,DLGAP4,ANXA4,IL18BP,RASL12,GALNT2,GORASP2,THUMPD1,TTC9C,PELO,GMPS,IGF1,CCR7,SNAP25,RXRG,MBD3,CDC23,DMPK,SYNGR3,TANK,BRAP,MPG,RDH11,PIH1D1,KCTD3,HAUS2,OR5M9,ELFN2,RP9,GALC,LRRC8A,SSPN,GNGT2,LBX1,NKAP,RPL26L1,PHF13,CGGBP1,KLHL1,FOXA3,CARTPT,SESTD1,ABHD12,BANF1,PARP2,NF2,GGH,TNF,PPAT,IL17F,NUDT9,CYGB,TFB1M,SUMO2,SNRPB2,LZTFL1,KLF3,CCR4,CHRAC1,CRISP1,DPH3,ELK3,LRRC40,CD81,MT1E,UBE2E2,FSTL1,HGS,RHOBTB3,POLDIP3,POLR2L,DBR1,TAS2R13,COX6B2,RNF133,TSPAN17,PRKRA,PRKCE,ZNF451,WDSUB1,GNRH1,ZDHHC4,WDR5B,CDC20,XRCC5,TIMP4,ACCS,SNRPG,TBC1D25,AIPL1,PEX13,NHEJ1,WDR11,SLC35B3,FHOD3,TYROBP,SEC13,IL2,TNFAIP8L1,NBN,VMAC,PRL,MPPED2,CDC7,SLC19A3,OLR1,NDST3,FBXO8,MGAT4A,RBBP8,SGMS1,MRPS34,IGSF11,CYP2C9,DUSP21,ATAD1,TRIM45,TPPP3,ZNF263,CA2,SNX10,USP6NL,MTDH,SGTA,E4F1,TMED9,GSTCD,GTF2F1,DLST,SSX2IP,BCL6,TRPC1,LYPD6,ELMO2,BCL9,ASPA,CBX3,DR1,GTPBP8,HS2ST1,MIS12,GABRA1,HSD17B10,CAND1,PRNP,TMEM89,PIK3AP1,LST1,PICALM,COX6C,XAF1,VTA1,RPIA,COCH,FEM1C,NUDT2,BAX,PEBP4,GH1,ATP1A3,PSD2,CRTC2,GSTM4,TSPAN15,TMEM38B,NPM3,IVNS1ABP,PIK3CA,FAM83B,JAKMIP2,CDH11,PSMC3,TMEM185A,NDUFS2,PAIP2,LY96,AP1S2,MAD2L1BP,TMEM47,AKR1B1,ADORA3,APEX2,SF3B1,TAB1,CPT1B,ZBTB39,CNN3,ANKMY2,DMTF1,PLG,CDK12,PSMB7,TNFAIP6,FBXW7,EPHA4,KCNJ2,ARL4D,LIAS,CITED1,TNNI3K,CPLX3,NPY1R,GCLC,PSMD10,PLCB1,GPR17,GPC1,PRSS23,ZNHIT6,ARL2BP,ING2,FRZB,SPP1,TSR2,CHRM3,GJA1,MAGED2,SURF2,SLC29A1,AASDHPPT,REEP4,TM4SF20,CCNA2,LSM14A,CAPN2,OR8H3,SLC8A1,ICAM2,ABHD8,YWHAZ,STARD3NL,TNR,OR6X1,BOK,CEND1,ZNF511,EHD4,FAM81A,SLC25A1,STAMBP,HOMER3,CXCR3,MAGEB10,GRM1,PCGF6,OR4K2,SHPRH,KCNJ10,SPATA2,SLCO3A1,ADORA1,TAF1D,B4GALT4,CAV1,LXN,TCEAL8,YIPF3,RPS2,RGL2,ITGB5,TRIM34,NDUFC2,NINJ1,ICOS,BLCAP,AKR1C1,MRPS11,RAB39B,CSNK1G3,CPLX2,PRND,HUWE1,ABHD10,FTSJ1,CNTROB,TTPAL,PMAIP1,CCIN,UBE2L3,MEPCE,CYP3A43,SPEM1,PDE4B,CREBZF,MRPS18C,NT5DC1,TRIM36,PROK1,JAK2,COMMD9,CBLN1,STK3,HSPB2,LILRA2,TNKS2,LY6H,PLSCR1,PTP4A3,DCAF12L2,ZBED1,TRIM29,CORO6,OIP5,RB1,DPH5,PNMA3,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,GPR35,DDAH1,HFE,NDUFA1,ALG11,OAF,SHMT1,NDUFA4,CYTL1,SLC45A3,HEXB,SYNGR4,PPFIBP1,THBS3,CALR,SNAI2,TRUB1,DRG2,MOBP,PKIG,MAMDC2,TSG101,ADCY2,OR10G2,RAB13,MAP1LC3A,RNF26,PATE2,CDK5,GNG3,MRPL51,PLAC8,CYB5R3,NDC80,RPP21,SNAPC5,SFTPC,ZC3H15,SLC25A23,ODC1,DSN1,NME4,FNTB,YIPF5,TOB2,SLC6A4,PDSS2,SDC4,CD79B,WASL,OR4N4,ZBED4,DYNLT3,SP4,BVES,RAB14,GOLGA7,TMCC1,REP15,NDUFB7,NEK2,NDUFV2,ZNF526,PC,RAB5A,APOBEC3D,TMEM31,PTN,SSBP1,F10,KCNA3,PAX6,STAT1,ZNF507,PRDX2,DPP4,LMO3,EIF2S1,UGP2,MRPS33,LMBRD2,IL3,CHRM1,MSX1,CD151,RPN1,KCTD9,TLR6,DLG1,P2RY11,EYA3,DUSP26,RNF39,HDAC6,PBLD,TMEM176A,ANAPC13,CNTNAP1,AGPAT1,ZMYM4,EIF2S2,BTG1,CHMP5,ASB3,TSC22D3,NANP,USP14,TXNL4A,CISH,CXCR6,GNA14,RRAS2,ATL1,TPT1,SNCB,RERG,POLR3F,RPL35,FRS3,RNF20,GPR15,COPS7A,PPARA,STOML2,OTUD6A,MICB,NUP153,GTF2A2,ACTL9,EEF1G,ARRDC3,ZCCHC12,NFYB,SLC25A17,PDE1A,DAPK1,LILRA1,TPBG,KCNQ5,STXBP6,SYT2,SPOPL,LEPROTL1,TMEM95,BMP1,NR1H2,PRPF31,MMADHC,TTC1,EDNRA,ST6GALNAC3,TBC1D24,ZNF692,SLC25A44,YWHAB,THY1,SESN3,CDSN,GZMK,FBP1,CENPP,RP2,STX12,NLRP1,CNPPD1,AOX1,PSMA5,STARD13,B4GALT1,ATP1A1,TGIF2LX,CRKL,GCC1,LRRN1,CD1B,DNAJC27,KDSR,DNAJB6,EGFL8,ILVBL,ARL15,AZI2,NDUFA12,NUDT5,GTPBP1,KCNMB2,RPS11,GSTK1,KATNAL1,TNFRSF14,TXNRD1,TMOD1,GNAI2,CDC123,UCK1,KCNMB1,TRMT1L,GABARAPL1,CD46,FAM118B,CBX5,ARL10,MYCT1,PEX5L,COMMD2,TM9SF1,MAGOHB,TMEM209,GFI1,GLYAT,MRPL52,MYD88,FCF1,CD1D,PLN,E2F4,DEDD,BOLA3,PPM1G,CDC42EP2,FLRT2,LCMT1,YIPF4,CSNK2B,MAX,OR4K17,RHOB,TMUB2,NRSN1,HOXB1,G2E3,GLRA1,TOPBP1,RBM18,QPCTL,RPL3,MTG1,PROM1,C1QL3,TRIM11,MRPS18A,LITAF,ARFGAP3,ARL4A,MEF2C,DRAP1,LRRC4,PLAA,RPRM,BAP1,DOHH,FUT1,IL1B,GPR26,PHAX,FKBP10,BAALC,RIMKLA,GPX4,EXOC1,FGF12,LY6G6C,RHCE,ANGPTL2,GOLPH3L,TNNT2,STK11,TESK2,COMT,RPS27L,SEC61A2,ELAVL4,SNRPD3,LAMTOR3,ZNF175,GPSM3,TP53INP2,DDX5,EIF4A3,RAP2C,LAMTOR1,ADNP,FOXP2,CYP17A1,UBE2F,UBN1,TPSG1,CYTH1,PDE9A,SLC1A1,CCDC71,CCHCR1,RPS5,SLC22A12,SNAPC2,COG1,RPL10L,SCYL2,ALG2,MBLAC2,PHKA1,SAT2,PRRG1,GPNMB,RAF1,IRF6,RGMA,DNAJC10,KLHL7,MCHR2,ZNF330,DET1,OR51A4,CSTB,GTF3C3,RNF14,RPAIN,TBC1D4,MORN4,GIMAP4,OR9K2,NDUFS3,HPGDS,RLN2,OSBP,GOLGA5,DNTT,PSMC1,MED21,SSRP1,PAIP1,OCIAD2,TWSG1,HECTD1,DYNC1I1,LGR4,FGF10,TLR2,CCDC122,PPP1R12A,IL6,GRID1,RERE,GABRB2,ARMC1,TFEB,HSCB,SYVN1,CES5A,LDHB,RPF1,FOXP4,TMEM182,RNF126,AKR7A2,FXR2,TM9SF4,TCEANC2,LRRC1,NUP37,USP5,MXI1,FERD3L,ITGAV,GPR85,PPP2R3A,SMAD4,SLC22A8,DRD1,SLC1A3,FZR1,DRAM1,VKORC1L1,IL1RAP,SMARCA5,ELK4,FAIM,BAK1,ATP1B1,CLVS1,FAU,CYP2F1,PSME1,KBTBD4,SMC4,GTF2E1,TNNC2,OR8I2,AK5,RAB22A,OR5AP2,ELAVL2,MOSPD1,ISCU,FCHSD2,AGAP1,SLC6A12,TRIM10,UBE2E3,UBE2M,PIR,ACTB,MATN4,DDAH2,CPNE1,GNB4,CNTN1,ZER1,RFC2,LNX2,SNX18,FOLR2,PDRG1,SOCS3,PTPN22,CD1A,LPAR1,HSP90AA1,HDDC2,PPIH,DCUN1D5,EPO,MMP21,EID1,CHCHD3,NFKBIB,PGAM1,AP2S1,RNF121,UGDH,RPS13,GABRA2,SST,COMMD5,PFDN4,NICN1,RAB30,RSAD2,EFHD2,PSMA2,DNAJB2,GRXCR1,GGT7,NAA35,GSTM2,UBFD1,PPP4C,NRBF2,PPIG,TAS1R2,DAD1,ZBTB2,MFN1,PLA2G12A,CAMLG,NPY,CNR1,RASGRP3,ENTPD3,RCE1,MGAT1,RGS19,IFIT2,RAB33B,SECISBP2L,MCM3,CDC42EP3,RNF115,SLC25A11,PAFAH1B1,KCTD15,PDCD1,MS4A7,PSMD12,CKLF,CCT7,HMX2,CHST11,MTMR6,NEUROG2,LUM,SEMA6C,CCDC85B,ICAM3,UNC50,MED31,SH3BP5L,YTHDF1,RPL7,TUBA1A,CELF6,NAA50,FCGR2A,MORC4,CISD1,PIK3R3,LANCL1,MKKS,SLC35B4,KRTAP12-4,VPS28,MPZ,SRC,CD2AP,RASL10A,METTL6,TUFM,OR51M1,GNG13,IFNA2,IDH1,NLRP6,CHRDL1,PSMB6,ZCCHC17,IZUMO1,PIP5K1A,TOMM20,TRAF3IP2,PTGER4,BAHD1,DHRS7B,RIMS4,NDUFA2,IFNGR1,NUP50,MOG,LRRC57,PLSCR4,OSGEP,NMI,SCN3B,PADI2,POLR2F,NDUFB10,POMT2,NSFL1C,OGN,SCPEP1,RRN3,DHPS,UTS2,GNG5,TMEM14B,NIF3L1,CYP27B1,PNOC,YBEY,NTPCR,IL15,MRPL10,TLE1,ARL6IP6,HMG20A,BTF3L4,RSRC1,RPL35A,CD248,ZNF668,KLHL12,SERPINI1,IDO1,PPM1D,SLC25A28,SLC39A3,MSL2,CXCL12,FLCN,GRPEL2,STIM1,TMC7,LRIF1,FTL,TNFSF13,FLRT3,RIC3,ARHGAP25,DES,PCDH9,ZRANB2,LIN7B,EIF4E3,MYOZ3,TCAP,VTI1B,GLT8D2,SPATA6,ZNF575,CCL20,MRPS7,ARHGAP5,CDC16,GNB1,GLTP,INPP5E,ORMDL1,ASB8,GHR,MED30,CXCL11,SOCS4,MED9,TREML1,PYCARD,CUL2,SLC6A8,FOXP3,LDLR,VPS4B,TMEM160,GSTA4,RHBDD3,PPP5C,RBM42,RASGEF1C,MAP2K6,CA10,MAD2L1,ANAPC11,LACRT,SEPHS1,TOMM7,LILRB1,EMP2,OVGP1,GPX2,DNAJC1,HCLS1,TRIM46,EHHADH,GLRB,TRIM63,PAQR9,THAP2,IL4,TIAM1,FAM110B,TUBB,LSM14B,ZFP64,COIL,FAM50B,STX10,ZNF596,RING1,MCHR1,SFN,TRAPPC10,SF3A1,PSPC1,GNAI3,CHID1,DISC1,AVPI1,SSR1,NETO2,SMARCD3,CDK8,RNASEK,BSCL2,PHF23,COX10,CYB5A,TFG,ELOVL3,MTX2,MAEL,VLDLR,CRB3,DHRS7,VAMP3,WDR83,HTRA1,KIF3B,IKBKB,HELLS,MITF,RPL13A,FAHD1,TRIM8,HRAS,WDR20,SYT4,RPP14,TAGLN2,IKZF2,CLEC9A,RPL8,PGM1,NAT9,HADH,GABRG2,TFIP11,PRKCQ,WASF3,SMCHD1,B4GALT7,ZSCAN5A,CLCA1,CNOT6L,GTF2IRD1,CD1E,TRMT11,MRPL40,RSPH1,MAP3K12,ZDHHC15,FBP2,PPIA,TMOD3,RPS4X,SOX3,COX19,DEFB121,NCKIPSD,CTSB,SKA3,RPS29,ALKBH2,LECT2,SLC16A4,POGK,TRIM52,ACOT8,HNRNPA1,NFE2,NR4A2,NOSIP,SFXN1,UBAC2,NME2,CD4,UBXN6,KCNF1,ACO1,GANC,PPTC7,PCK2,G0S2,OR5I1,SATB1,TRA2A,PRMT5,BEND6,DYRK1A,DRP2,RAB31,STC1,OR8K1,KLHL32,SRGN,TSHR,SLC25A20,NEUROD6,AIG1,INSM2,EIF2D,EIF2AK2,C1GALT1C1,LGI3,GTPBP2,LIMD2,COPS2,TRIM27,NXPH3,SSBP3,DEFB115,NOL7,SNX2,CAMK1,WFDC5,NSA2,IRF2,TM4SF1,BCCIP,ERP29,PTTG1,NOVA1,MCAT,NUDCD3,SEC63,CDC40,SCN1B,TM2D2,NDUFB5,OR52W1,SUB1,NELL2,DCAF4,ARHGEF6,PCSK2,SLC39A13,CPE,CYP4F12,LRTM2,CYB5R1,USP2,MYT1L,REXO2,GPHA2,POC1B,HP1BP3,PACRG,TAS2R16,IL13,EIF4E2,GRM8,UTP15,MCM8,CAMK2N2,CUTA,DLAT,RMI1,RIMS3,MT1A,CD38,PNMA2,ANKRD49,BLOC1S3,PHC1,TAAR6,PLXNC1,UGT2A3,GRAP,EPYC,DCP2,MED17,NOB1,TMEM184C,PHF12,ZBTB33,GEMIN7,BAG2,RNF41,ZNF7,DCAKD,PLP1,XPNPEP1,MGAT4B,CD52,CYP3A5,DCUN1D3,LMNA,PHF1,IRAK1BP1,TIMM8B,TMEM74,CTBP1,EIF3E,CDC42EP4,MSRB3,JUP,DDT,ALKBH3,EXT1,KLRD1,FASLG,SNX5,CFL2,SLMAP,OR4N5,ZMYM2,EXOSC4,BUB3,PRPF18,IGSF21,CDK2AP2,FGF7,MAPRE2,CAV3,EPHA2,UCK2,LMBRD1,SRSF1,DIO3,SLC31A1,COX6B1,ITGA2,DCLRE1C,OR10G3,OR2J3,G3BP2,EXOSC8,ZNF574,KLHDC8A,POLD2,KDM2A,SUMO1,TSPAN7,IFT52,ACOX1,FADS2,F7,PIK3R1,NCALD,ANGPT1,COPS4,KCNK17,KLHL23,HSDL1,ACOT6,IL12B,WDR6,INSIG2,DEFB124,LHB,CBL,ATP6V1G2,RAB6B,MMP14,MRPS35,MRAS,RALYL,MRPL41,DDI1,RAB28,COX17,ELK1,FAM168B,CYP1B1,MDH1,UBL4A,SERPINB11,GKAP1,PI15,HECTD3,FGL2,HDAC5,SLC25A42,VAC14,CLIP3,CRYGA,GRIA1,YES1,GAPDH,NEO1,PCCB,HSD17B3,ESAM,NXT1,SLC35C1,RLN3,ANKRD50,JRKL,RFC5,IDH3A,TMEM97,MED13L,NSDHL,MFSD6,POU3F4,MADCAM1,ASRGL1,MPST,PSMC4,CCAR1,NTRK3,PICK1,TSSK1B,BOLA1,GGCX,PAQR4,RNF146,SAP30L,FAM76B,SNAP23,PDIA2,CLDN6,CAPZA1,OR4N2,STAC3,FAM3A,MNAT1,FMO3,TNFSF10,CDK5RAP3,NEK9,IRF2BP1,CSE1L,UBE2B,ACHE,AGAP2,GUK1,STX1A,FBXO3,ACVR1,VDAC2,DCTN6,MYH1,IFT57,LYZL4,CST3,PLEKHO2,ICA1,BCL2L1,YWHAG,KCNB1,TNFRSF9,ZNF32,NOP16,DMAP1,LRRC8C,PPP1CC,PAQR8,BAZ1B,PEX26,OR4E2,OR7D4,CYP7A1,DIRAS1,ABCE1,PRRT1,GINS4,SDS,ADH1A,EAF2,DCK,ITM2A,RPS24,MCM6,NUDT4,DCUN1D1,SPOP,DEFB129,TRIM22,CYB5R4,MRPL36,NR0B1,AMACR,TPRA1,SASH3,TIFA,B2M,CASP4,SLC15A2,LRAT,ZDHHC8,ISOC1,EDDM3B,RETN,NKRF,MCPH1,PSMB11,HSP90B1,TCOF1,ASB1,RPS15,QRSL1,VIPR1,FBXL3,GATAD1,RGS10,PTGES3,ACTN4,DUSP9,CFDP1,SIGMAR1,IFNK,ATP2B4,CXCL9,RBPJ,MRPL17,RNF152,UQCRC2,MRPL33,LRRTM1,EGLN2,KLHL28,EDEM3,TPPP2,CD80,EMX1,PKIB,UBTD2,IREB2,TAF11,CNOT7,ADRM1,RABIF,OR2F1,CH25H,HPS6,TCP1,KCNH8,CRMP1,CDC5L,LGI1,SLC35A5,TMEM19,ARMC6,CHCHD1,SIKE1,NDN,SNX3,CLRN1,DBH,TBC1D5,RUVBL2,GOSR1,IGF2BP1,NCOA5,MMAA,PPIC,LPAR6,POLR2C,GNAQ,RAD1,GIPC3,DBNDD1,NGRN,NFE2L2,CCDC167,USP46,SMAD2,PITPNB,ADRB2,TLR4,SLC6A1,GPN2,MYO1B,SLC2A1,QSER1,SRSF12,GPT,COL3A1,CBX7,PAK1IP1,VAMP1,PEBP1,ADRA1A,TNNI1,FGF22,CX3CL1,PSMB2,VDR,CTTNBP2NL,PTGDS,IL5,PSKH1,STX16,FKBP4,EIF5A2,PI3,SMURF1,DPPA2,PMP2,ANO3,UBE2N,CCL1,PFDN1,SSR3,LIN7C,SGMS2,NCSTN,ANXA7,TAF2,P2RY10,NKX6-2,GPR22,SLC38A2,PLAC9,HS3ST5 |
| 5.314e-26 | -58.20 | regulatory ncRNA-mediated post-transcriptional gene silencing | biological process | GO:0035194 | 601 | 298 | 18204 | 5365 |
MIR139,MIR770,MIR216A,MIR1-1,STAU1,MIR135B,MIR34A,NCBP2,MIR609,MIR143,MIR15A,MIR34B,MIR133B,MIR873,MIR671,MIR188,MIR7-3,MIR583,MIR148B,MIR590,MIR147A,MIR140,MIR601,MIR586,MIR939,MIR340,MIR765,MIR891B,MIR572,MIR99B,CNOT8,MIR26B,MIR34C,MIR155HG,MIR195,MIR549A,MIR652,MIRLET7G,MIR29A,MIR874,MIR198,MIR554,MIR1249,MIR542,MIR28,MIR335,MIR638,MIR137,MIR769,MIR455,MIR298,MIR422A,MIR934,MIR181C,MIR194-2,MIRLET7I,MIR532,CNOT7,MIR218-1,MIR296,MIR563,MIR503,MIR618,MIR212,MIR551A,MIR626,MIR153-1,MIR30A,MIR493,MIR625,MIR944,RAN,MIR100,MIR24-2,MIR193A,MIR711,MIR193B,MIR922,MIR301B,MIR218-2,MIR106A,MIR30E,TNRC6C,MIR624,MIR145,MIR191,MIR920,MIR636,MIR363,MIR505,MIR9-2,MIR24-1,MIR101-1,MIR1298,MIR567,MIR611,MIR640,MIR875,MIR616,MIR98,MIR208B,MIR1296,MIR649,MIR653,MIR361,MIR23A,MIR592,MIR628,MIR129-2,MIR23B,MIR205,MIR495,MIR924,MIR599,MIR615,MIR338,MIR141,MIR16-1,MIR491,MIR424,MIR937,MIR301A,MIR7-1,MIR105-1,MIR16-2,MIRLET7C,MIR378A,MIR657,MIR552,MIR632,MIR581,MIR32,MIR1277,MIR1180,MIR181D,MIR502,MIR214,MIR802,MIR17,MIR183,EIF4E2,MIR373,MIR222,MIR764,MIR761,MIR184,MIR484,MIR379,MIR1-2,MIR126,MIR553,MIR633,MIR302B,MIR107,MIR556,AGO1,MIR490,MIR142,MIR106B,MIR190A,MIR223,MIR185,MIR605,MIR200A,MIR3173,MIR216B,MIR942,MIR7-2,MIR557,MIR10A,MIR130B,MIR589,MIR449A,MIR607,MIR1225,MIR186,MIR105-2,MIR190B,MIR132,MIR1224,MOV10,MIR885,MIR194-1,MIR452,MIR210,MIR129-1,MIR593,MIR887,MIR33B,MIR150,MIR454,MIR197,MIR876,MIR101-2,MIR661,MIR760,MIR204,MIR577,MIR423,MIR375,MIR149,MIR324,MIR96,MIR30B,MIR21,MIR519D,MIR648,MIR146A,MIR651,MIR208A,MIR548C,MIR330,MIR196B,MIRLET7D,MIR148A,MIR342,MIR504,MIR383,MIR662,MIR580,MIR31,MIR612,MIR1227,TSNAX,MIR345,MIR9-1,MIR877,MIR604,MIR384,MIR449B,MIR346,MIR331,MIR675,MIR370,MIR639,MIR597,MIR192,MIR144,MIR99A,MIR92B,MIR152,MIR1226,MIR147B,MIR9-3,MIR940,MIR595,MIR211,MIR374A,MIR517B,MIR182,MIR1271,MIR30D,MIR578,MIR600,DHX9,MIR569,MIR938,MIR367,MIR25,MIR136,MIR936,MIR511,MIR450B,MIR448,MIR488,MIR10B,MIR558,MIR200C,MIR425,MIR500A,MIR29C,TSN,MIR1260B,MIR573,MIR125A,MIR339,MIR187,XPO5,MIR708,MIR489,MIR221,MIR155,MIR130A,MIRLET7B,MIR497,CNOT6,MIR492,MIR215,MIR377,MIR656,MIR551B,MIR631,MIR20A,MIR320A,MIR1251,MIR206,MIR429,MIR643 |
| 5.838e-26 | -58.10 | DLD (dihydrolipoamide dehydrogenase) | protein interactions | 1738 | 463 | 236 | 19454 | 5460 |
JUP,CDK1,HSP90B1,RARS1,PSMC4,EEF1E1,UQCRC1,PDHB,PPM1G,RPA3,SIRT7,IDH3A,CHORDC1,PYCR2,NONO,LDHA,TXN,COPE,CCNF,EIF2AK2,CTNNA1,EIF4A3,SNX12,RTRAF,DTYMK,ACAT1,NDUFS3,AP1S2,SOD2,ILF2,SRP72,MRPL11,HUWE1,FARSA,TTC4,THRAP3,TF,ARF4,VTA1,OLA1,SMN1,PTGES3,ABHD10,RAB1A,SEPTIN7,EMC2,HSD17B10,NME2,PSMD7,DNAJC4,ISYNA1,HDAC6,ATP1B1,EIF2B2,DBT,CDK9,AIFM1,RPL12,CXCL14,RB1,SEC23A,KCTD12,ARCN1,ANXA7,EHD1,PRDX3,TIMM13,ETF1,UCHL3,PSMC1,SKP1,YWHAZ,TNFAIP8,HTRA2,FMC1,RAB11A,SMARCE1,TOMM40,MCM4,GGH,MCM3,PRDX2,MRPL23,RBBP4,DYNLL1,SIAH1,ERH,ARF1,EIF3K,UBE2S,NME1,POLR2C,ANP32A,FEN1,HSDL2,OTUD6B,ACTN4,PPP2R1A,UFM1,RBBP7,G3BP1,ETFA,AP1M1,MCM6,COPS4,HNRNPA2B1,BAG2,COX8A,DDX23,PSMD10,RPL23,PRPF19,PSMD3,STOML2,MRPS35,SIAH2,EIF3D,COPS7B,SNX1,SNX2,ATXN10,CACYBP,PBDC1,GATD3,RPA2,UBE2M,GSTP1,HECTD1,CDC42,UBE2K,OGDHL,RPL27,BANF1,HNRNPH2,RNF113A,DLAT,PRDX6,EIF3G,ATP1B3,OAT,ATP1A1,UBE2H,MAT2A,NAA50,CARS1,SUB1,CFL2,GORASP2,BUB3,ADRM1,SUCLG2,CSTF3,SF3B6,PSPC1,UQCRC2,PAFAH1B3,CSNK2B,PITPNB,PSMC5,MACROH2A1,TFCP2,NUPR1,PSMC3,ACTR1A,REXO2,MRPS18B,H2AC4,RPL10A,PGAM1,API5,SPPL3,MIF,DKC1,TMPO,EEF1B2,SDHB,UBE2N,MGME1,CNDP2,SEC62,UFL1,NDUFS2,HNRNPA0,EEF1G,BOLA2B,DDX39B,XRCC5,STK26,CKB,CCT2,H2AZ2,FBXW11,H1-10,ATG3,SERPINH1,MDH1,LDHB,CUTA,PSMD4,PSMD6,DLST,SMU1,MRPL13,PLS3,UCK2,PDHA1,ETFB,EEF2,KRAS,KGD4,RUVBL1,DCTPP1,HNRNPDL,PRPS1,NDUFB5,CCT8,PABPC1,RUVBL2,SCPEP1,PDIA6,RTCB,AK2,AGR2,DDX1,YWHAB,RAB5C,MRPL9,YWHAH,YWHAG,XPO1,DDRGK1,EIF2S1,AASDHPPT,CCT7,MACROD1,S100A8 |
| 6.230e-26 | -58.04 | RAF1 (Raf-1 proto-oncogene, serine/threonine kinase) | protein interactions | 5894 | 1845 | 716 | 19454 | 5460 |
NEU1,LYPLA1,BUD23,RAF1,PPP2R1A,CTNNA2,SNRPE,HNRNPA2B1,BCKDK,HSPD1,PCNA,CDK20,S100A10,DHX16,FLOT1,INO80E,ZNF207,DICER1,MED4,KRT8,DNAJB9,DHX15,TMEM237,SRSF10,RFXANK,LARP4B,ISOC1,MFAP1,NKAPD1,PSMA3,ATP6V1G1,FBXO30,PYGB,STX7,TMED4,AUH,NIBAN2,SMARCE1,PFDN2,HSP90AA1,FAM91A1,SEC61B,SNRPD2,LRRC8A,PRRC2A,ERH,GBE1,FBP1,AURKAIP1,TAF1D,NDUFS3,LLPH,DTD1,TCOF1,TMED1,NKRF,RAB1A,FARSA,NOC4L,TSSC4,GRSF1,MOV10,ERCC3,ATP1B1,HM13,OSBPL8,ALDH1A3,HRAS,RB1,DECR2,TSC22D3,THOC1,NCBP2,PCK2,SF3A1,SPMIP6,CHMP1A,RARS1,RDH10,NF2,BRIX1,HSPA14,RACGAP1,TRAF3IP2,POP7,METAP2,CCNF,HEXIM2,CMBL,RPP25L,COPE,H1-3,PTRH2,PLS3,SMARCB1,LSM14A,RUVBL1,XPNPEP1,TFG,RAB18,RAB5C,WWP2,CTNNB1,DKK1,YWHAG,DRG2,GSTO1,AK2,ANXA4,MRAS,WDR82,SNRPD3,RAB1B,DBR1,HSP90AB1,CHMP2A,CCT7,TRMT61A,MAP2K1,MED31,SPECC1L,DDX39B,PEBP1,PHB2,FXR2,SRSF2,PACSIN3,ITGAV,SFN,PSMA4,SNRPB,CUTA,CKB,MDH1,MIDEAS,INTS10,RRAS2,SMU1,TAX1BP1,TAGLN2,MATR3,STAT1,PSMB6,KBTBD4,CBX3,ZNF451,TSPO,SMCHD1,TMEM70,MED27,AKAP8L,UBE2N,ALYREF,CDK6,RAP1B,ADD1,CPNE1,LMAN1,TRIM3,TMEM263,RBM23,SNX33,DLAT,LSM12,PGK1,FTSJ1,NME4,GRPEL1,WDR55,RAB2A,ST13,CFL1,ALKBH5,RBM7,UQCRC2,PSPC1,SEC61A1,SRP54,RBMX2,RPGRIP1L,CDC20,GTF2E2,ASPM,RBM38,GFPT1,CTSA,GTPBP1,MORC2,PLSCR1,TRIP4,SRSF8,INO80C,RFC2,FAM174A,CLPX,PRPF19,TRA2A,EIF3D,HBA1,CSTA,DDX23,PPP2CB,THOC2,WDR6,BUD31,CETN2,NDUFS8,ERLIN1,CGGBP1,WDR77,RAB6A,PPP1CB,PRDX3,THOC3,HADHA,SKP1,COIL,GRB10,NOP16,RBM15B,RHEB,LMNB1,PIGK,RAN,UMPS,DYNLL1,AKR1C2,GNB1,SNRPB2,TBK1,RPL15,LBR,EEF1A1,STX8,NSDHL,SNAP23,PC,THRAP3,CTNNBL1,PAK1IP1,PRDX4,ARF4,CALR,APOBEC3F,LRRC40,CRBN,SRPRA,HACD3,SRP14,ATP5PD,AKAP17A,EEF1E1,CPSF4,PSMC4,CNP,TMOD1,ZNF574,GTF2I,NPM3,NHP2,MBD3,FLRT3,CDC16,PPP1CC,KPNA6,LGALS8,CASC3,EPHA2,NAPA,STUB1,UBE2I,LDHA,RAB14,SMNDC1,RAB4A,CRKL,KLHL12,CCT8,RTCB,FBXO11,KRAS,RIOX2,IQSEC1,PPIB,HSPB1,DRG1,MPDU1,SRSF1,MAGED2,TRIR,VAMP7,TMEM97,EHHADH,PYM1,RAP2A,RAB5A,RER1,SAP18,COPS7A,FTSJ3,RBBP8,LAMTOR1,MCAT,THOC6,ICAM1,SNRNP40,ATP5F1B,IREB2,MTCH2,RAP1A,SRFBP1,NAA35,WBP11,ACOT13,TFCP2,SLC25A11,SNIP1,MRPS18B,TMEM33,SRPRB,CDC40,RBM17,KARS1,GPRASP2,COPS5,CDK12,COMT,COQ8A,NKAP,DKC1,TMPO,RBM42,SNRNP27,UGDH,CEP85,SPRED1,PCBD1,CALU,ACOX1,MRPS28,ABHD14B,PRKCE,BUB3,BCCIP,SRPK2,SRC,SUCLG2,NME1,PPID,RAB19,RPN1,SART3,DHRS3,MAEA,SLC25A5,BAG2,SRSF7,FAM76B,SSRP1,HMGA1,PIK3R1,PDIA3,DROSHA,WDR12,HAX1,MRTO4,ATP6V1A,PLEKHO2,AGK,STK3,EGLN3,PGRMC1,VPS18,ERAS,VAPB,SLC25A3,ARCN1,PRKD3,C1D,TERT,ADGB,BIRC2,SRI,YTHDF1,PPP2R2C,CDSN,F2,PYCR1,RAB11A,YWHAZ,ILK,LSM14B,RSRC1,TRMT6,BAD,SNRPD1,TUBB,LGALS3,JAK2,CCT5,FCF1,MAP2K3,CD2BP2,PQBP1,FN3KRP,HUWE1,SMN1,SPATS2L,KRR1,COX20,CWC15,ASNSD1,FTH1,STOM,ZCCHC17,SHOC2,MET,SOD1,DVL2,PPIH,IRF7,PDHB,DAD1,RALB,BRAP,GGCX,PPIG,AP2A1,NRP1,EIF2AK2,ENO1,MGST3,GNAI2,VIRMA,DEK,PDCD5,ETFB,MIEF1,EEF2,PDHA1,TUBB4B,RPS23,TAF10,SERPINA5,APTX,BCL7B,MYO1B,EWSR1,HNRNPF,DCP2,TFPI,PRPS1,SECISBP2L,MX2,CCAR1,SEC61A2,LAMP2,QPCTL,NGDN,YWHAH,DNTTIP1,XPO1,ARHGAP5,AVL9,RBM5,FUBP3,SUMO3,ISG20L2,PEG10,SEC62,CSNK1A1,NUFIP2,NGRN,RAMAC,SF3B1,EEF1G,LDHB,HNRNPC,MYC,CPSF2,KANSL3,CCT2,CIRBP,RCL1,SERPINH1,DLST,VDAC2,ADH1B,POLR2B,TP53,STRBP,CAPZA2,BIRC5,CLPB,CSE1L,MRPS33,NUP107,PSMA5,CTSC,RDH11,DPP4,GAPDH,TPM3,ELOC,PPIL4,CHCHD1,MAP4,TAF9,PEBP4,MGME1,ACSL4,SSBP1,TMED9,MYL12A,IGFBP3,LUC7L3,TFB1M,TFIP11,DDX46,BAP1,OIP5,WDR3,BCL6,SLC25A1,AKT1,SMARCA5,MECP2,IGF2BP1,SF3B6,MACROH2A1,PHAX,CSNK2B,CTSB,RNASEH1,UBA3,TMT1B,MARCKSL1,FEN1,DCUN1D3,MAK16,CYB5B,PLD3,AP2S1,SF3B5,NDUFA4,CDKN2C,ERP29,SLC39A7,JAK1,ETFA,GNL1,LASP1,G3BP1,RFC3,DMPK,NQO1,BCL2L1,LYZ,RSBN1L,PHB1,HP1BP3,RPLP1,SPTAN1,RPL7,CCAR2,ATXN10,NOP58,EHD1,NRDE2,MYL6,UPF3B,LUM,MCRIP2,NUBP2,CCDC86,TRUB1,G3BP2,UNC45A,FTL,CUL3,CFAP20,GALE,MCM3,SAMHD1,RIOK2,MYO6,PFDN6,CYB5R3,ARF1,CPSF1,AP2M1,RMDN3,RBBP4,MAD2L1,AKR1C1,YTHDF2,CCDC47,POP5,PSMB9,RAD23B,ILF2,SLC25A10,RING1,HSPE1,CTNND1,OLA1,ESYT1,EEF1AKMT3,MAP2K6,AIFM1,SEC23A,TOP1,ARF6,WDR83,SAP30BP,EDF1,HSP90B1,CDK1,TOX4,NOL7,SIRT7,CCDC106,MTDH,SQSTM1,AATF,CRYZ,SEC13,IL2RB,TUFM,NONO,AR,ATP5F1A,SULT1A3,ACAT1,RTRAF,PRKRA,MAGOHB,SEC63,TECR,CAAP1,STMN2,MTA2,RBM3,PABPC1,PDIA6,RUVBL2,VDAC1,POLDIP3,DIRAS2,SHC3,FKBP4,YWHAB,SMAD9,TNIK,S100A8,TCP1,LYAR,FAM98A,MEAF6,PAK2,XRCC5,RFC4,AKAP1,STK26,HSPA8,STAU1,SSR3,RNF41,RANBP10,RBM27,CHTOP,SPCS3,DNAJB6,NSA2,PHF21A,GPNMB,CDK4,ACTR1A,RBM34,ACADSB,GPD2,ATP2B4,NOSIP,RAB27A,CMSS1,TMA16,CSNK2A1,NXT2,SNRNP70,BECN1,TUBG1,PSMG2,AIP,GRM1,SELENOI,SPTBN1,GTF3C4,ZNF326,SDCBP,WRAP53,PRKCA,APMAP,PRDX6,KDM1A,HSPA5,GSTK1,MGST2,NCAPG2,RC3H2,SNX5,RRP7A,SERPINB1,ATP1A1,PSMA6,RALA,PPP1R10 |
| 9.799e-26 | -57.58 | regulatory ncRNA-mediated gene silencing | biological process | GO:0031047 | 673 | 325 | 18204 | 5365 |
MIR147A,MIR590,MIR148B,HNRNPA2B1,MIR140,MIR601,MIR939,MIR586,MIR26B,NRDE2,MIR340,MIR765,MIR572,CNOT8,MIR99B,MIR891B,MIR155HG,PIWIL3,PIWIL4,MIR34C,PRKRA,MIR216A,STAU1,MIR1-1,MIR139,MIR770,MIR143,MIR609,ZC3H7A,MIR15A,MIR135B,DDX5,NCBP2,MIR34A,MIR671,MIR873,MIR188,MIR34B,HENMT1,MIR133B,MIR7-3,MIR583,MAEL,MIR618,MIR503,MIR563,MIR551A,MIR212,MIR218-1,MIR296,MIR30A,MIR153-1,MIR493,MIR626,MIR193A,MIR24-2,MIR100,MIR625,RAN,MIR944,MIR30E,MIR711,MIR193B,MIR218-2,MIR106A,MIR922,MIR301B,MIRLET7G,MIR652,MIR195,PIWIL1,MIR549A,MIR554,MIR198,MIR874,MIR542,DROSHA,MIR1249,MIR29A,MIR137,MIR638,MIR769,MIR28,MIR335,MIR532,MIRLET7I,CNOT7,MIR934,MIR298,MIR422A,MIR181C,MIR455,MIR194-2,MIR208B,MIR649,MIR1296,MIR616,MIR875,MIR98,MIR592,MIR129-2,MIR628,MIR23A,MIR361,MIR653,MIR495,MIR23B,MIR205,MIR924,MIR599,MIR615,MIR191,MIR145,MIR920,MIR624,TNRC6C,CNOT6L,ELOC,MIR363,MIR9-2,MIR505,MIR636,MIR640,MIR611,MIR567,MIR1298,MIR101-1,MIR24-1,SMAD3,MIRLET7C,MIR32,MIR632,MIR552,MIR581,MIR1277,MIR657,MIR378A,MIR502,MIR17,MIR214,MIR802,MIR181D,MIR1180,MIR222,MIR764,MIR183,EIF4E2,MIR373,MIR16-1,MIR141,MIR491,TERT,MIR338,MIR301A,PABPC1,MIR424,MIR937,MIR7-1,MIR16-2,MIR105-1,MIR589,MIR449A,MIR557,MIR10A,MIR130B,MIR1225,MIR607,MIR190B,MIR105-2,MIR186,MIR1224,MOV10,SNIP1,MIR194-1,MIR885,MIR132,MIR1-2,MIR553,MIR633,MIR302B,MIR126,MIR184,MIR379,MIR484,MIR761,AGO1,MIR490,TDRD7,MIR142,MIR107,MIR556,MIR190A,MIR223,MIR106B,MIR942,MIR216B,MIR3173,MIR7-2,MIR200A,MIR185,MIR605,MIR324,MIR375,MIR149,MIR146A,MIR519D,MIR648,ARB2A,DGCR8,MIR21,MIR30B,MIR96,MIR548C,MIR330,MIRLET7D,MIR196B,MIR651,MIR208A,MIR504,MIR31,MIR580,MIR662,MIR383,MIR148A,MIR342,SMAD2,MIR129-1,MIR593,MIR210,MIR452,MIR197,MIR454,MIR33B,MIR887,MIR150,MIR661,MIR876,MIR101-2,MIR760,MIR423,MIR204,MIR577,MIR92B,MIR152,PIWIL2,MIR99A,MIR211,DDX4,MIR595,MIR940,MIR9-3,MIR147B,MIR1226,MIR578,MIR30D,CLP1,MIR374A,MIR517B,MIR182,MIR1271,MIR938,MIR136,MIR25,MIR367,DHX9,MIR569,MIR600,MIR1227,MIR612,MIR345,MIR877,MIR9-1,TSNAX,CNOT2,MIR449B,MIR346,MIR604,MIR384,MIR639,MIR144,MIR597,MIR192,MIR675,MIR331,MIR370,MIR130A,MIR221,MIR155,DICER1,MIRLET7B,MIR489,CNOT6,MIR215,MIR492,MIR497,MIR631,MIR320A,MIR551B,MIR20A,MIR1251,MIR656,MIR377,MIR643,MIR429,MIR206,MIR450B,MIR511,MIR936,MIR558,MIR10B,MIR488,MIR448,MIR29C,TSN,MIR425,MIR200C,MIR500A,SMAD1,XPO5,MIR187,MIR708,MIR125A,MIR573,MIR1260B,MIR339 |
| 1.153e-25 | -57.42 | post-transcriptional gene silencing | biological process | GO:0016441 | 611 | 301 | 18204 | 5365 |
MIR384,MIR604,MIR346,MIR449B,MIR370,MIR331,MIR675,MIR144,MIR639,MIR192,MIR597,MIR612,MIR1227,TSNAX,MIR877,MIR9-1,MIR345,MIR1271,MIR517B,MIR182,MIR374A,MIR578,CLP1,MIR30D,DHX9,MIR569,MIR600,MIR136,MIR25,MIR367,MIR938,MIR99A,MIR152,MIR92B,MIR1226,MIR211,MIR595,MIR940,MIR147B,MIR9-3,MIR500A,MIR425,MIR200C,TSN,MIR29C,MIR339,MIR125A,MIR573,MIR1260B,MIR708,XPO5,MIR187,MIR936,MIR450B,MIR511,MIR488,MIR448,MIR10B,MIR558,MIR656,MIR377,MIR1251,MIR20A,MIR320A,MIR551B,MIR631,MIR429,MIR206,MIR643,MIR489,MIRLET7B,MIR130A,DICER1,MIR221,MIR155,MIR497,MIR215,MIR492,CNOT6,MIR106B,MIR223,MIR190A,MIR200A,MIR605,MIR185,MIR7-2,MIR942,MIR216B,MIR3173,MIR184,MIR484,MIR379,MIR761,MIR633,MIR553,MIR302B,MIR126,MIR1-2,MIR556,MIR107,MIR142,AGO1,MIR490,MIR105-2,MIR186,MIR190B,MIR132,MIR194-1,MIR885,MIR1224,MOV10,MIR130B,MIR557,MIR10A,MIR449A,MIR589,MIR607,MIR1225,MIR101-2,MIR876,MIR661,MIR423,MIR204,MIR577,MIR760,MIR210,MIR452,MIR593,MIR129-1,MIR150,MIR33B,MIR887,MIR197,MIR454,MIR208A,MIR651,MIRLET7D,MIR196B,MIR330,MIR548C,MIR342,MIR148A,MIR31,MIR580,MIR662,MIR383,MIR504,MIR149,MIR375,MIR324,MIR30B,MIR21,MIR96,MIR146A,MIR519D,MIR648,MIR636,MIR9-2,MIR505,MIR363,MIR1298,MIR101-1,MIR24-1,MIR640,MIR567,MIR611,TNRC6C,MIR191,MIR145,MIR920,MIR624,ELOC,MIR23B,MIR495,MIR205,MIR615,MIR599,MIR924,MIR98,MIR616,MIR875,MIR649,MIR1296,MIR208B,MIR23A,MIR361,MIR653,MIR129-2,MIR628,MIR592,MIR7-1,MIR105-1,MIR16-2,MIR338,MIR491,MIR16-1,MIR141,MIR937,MIR424,MIR301A,MIR1180,MIR181D,MIR214,MIR17,MIR802,MIR502,MIR373,EIF4E2,MIR183,MIR764,MIR222,MIRLET7C,MIR378A,MIR657,MIR1277,MIR32,MIR632,MIR552,MIR581,MIR133B,MIR34B,MIR188,MIR671,MIR873,MIR583,MIR7-3,MIR770,MIR139,MIR1-1,STAU1,MIR216A,NCBP2,MIR34A,MIR135B,MIR15A,MIR143,MIR609,MIR99B,MIR572,CNOT8,MIR891B,MIR765,MIR340,MIR26B,MIR34C,MIR155HG,MIR148B,MIR590,MIR147A,MIR939,MIR586,MIR140,MIR601,MIR335,MIR28,MIR769,MIR137,MIR638,MIR194-2,MIR298,MIR934,MIR422A,MIR181C,MIR455,CNOT7,MIR532,MIRLET7I,MIR549A,MIR195,MIRLET7G,MIR652,MIR29A,MIR542,MIR1249,MIR554,MIR198,MIR874,RAN,MIR944,MIR625,MIR193A,MIR100,MIR24-2,MIR106A,MIR218-2,MIR301B,MIR922,MIR193B,MIR711,MIR30E,MIR296,MIR218-1,MIR551A,MIR212,MIR618,MIR503,MIR563,MIR626,MIR493,MIR30A,MIR153-1 |
| 1.878e-25 | -56.93 | UBL4A (ubiquitin like 4A) | protein interactions | 8266 | 342 | 187 | 19454 | 5460 |
RAB11A,USP13,PRPF31,WDR20,HSP90AA1,RPS5,SEC61B,RPS9,SNRPD2,RPL37A,TUBB,SPINDOC,ACTB,RPL19,ERH,PGRMC1,WDR77,RFXANK,VAPB,ATP5PO,SLC25A3,ATP5MK,PXMP2,STX7,VPS26A,PRDX1,TRAF6,RPL23,PHB1,RPL8,RPL9,RPLP1,RPLP2,THY1,SPTAN1,RPL7,EGLN3,ERLIN2,FAF2,RPL29,RPN1,SNRPE,RNF126,RPS11,HNRNPA2B1,NDUFA4,HSPD1,SLC25A5,RPS24,JAK1,RPS27A,TUFM,ATP5F1A,RPL26,FBXO7,TUBA1B,CTTN,MRPL53,RPS20,RPS12,ACAT1,RPL13A,SLC25A4,RAB14,TXN,RPL22,TECR,UBA52,SEC22B,RPS14,UQCRC1,GRM2,RPLP0,RPL4,MOV10,ACTA2,EEF1AKMT3,RPL12,HACD3,SRPRA,RB1,ZBTB2,ATP5PD,CDK9,NDUFA2,RPL15,EEF1A1,SOD2,ILF2,TMED1,PQBP1,RAB1A,FAF1,RPL23A,SEM1,HUWE1,PRDX4,SMN1,HNRNPAB,HNRNPC,LDHB,UFD1,RBM27,PSMD14,SERPINH1,RPS26,LMBR1L,PRMT5,ATP5F1B,RPL10,RPL27A,FDFT1,RPS28,HSPA8,RER1,PHB2,RPL6,FAM20B,PPIB,HSPB1,RAB35,CORO1C,SNRPD3,RPS10,RAB1B,HNRNPL,HSP90AB1,TOP3B,KIF2A,EEF2,RPS7,TUBA1A,TUBB4B,RPL18,PABPC1,RPL31,HNRNPF,RAB8B,PAEP,RPS4X,CDCA7L,RPL28,CCAR1,RPL7A,PSMB2,SUGP1,RPS17,ANAPC4,ABCG2,CDIPT,RPS3,SGTA,TRIM54,SRC,SPTBN1,CFTR,PRKCA,RPL27,HNRNPH2,HSPA5,RPL24,SNRNP70,RPL10A,RPS2,UBE2G2,RPL32,SSBP1,SYNCRIP,ARL6IP5,TMED9,RPS16,FZR1,CDC5L,ILVBL,RPSA,FAM162A,SURF4,CDK8,CERK,SLC25A11,MAP1B,RPL3,RAB13,KPNA2,SRPRB,HNRNPK,PDE12 |
| 2.208e-25 | -56.77 | negative regulation of gene expression | biological process | GO:0010629 | 1553 | 641 | 18204 | 5365 |
HNRNPA2B1,CD200,MIR601,MIR140,MIR939,ATF4,POLR2G,HNRNPK,MIR148B,MIR34C,SRC,SMARCA5,ANGPT1,PIWIL3,MIR765,MIR572,MIR891B,SRGN,NRDE2,MIR135B,LGR4,MIR143,MAGOHB,MIR15A,PDCD4,MIR139,PRKRA,STAU1,MIR7-3,IFNG,MIR34B,TENT2,PIK3CA,MIR873,EIF4EBP3,MIR153-1,METTL14,MIR493,H2AJ,MIR218-1,TLR8,MIR296,IFI16,MIR618,MIR563,MIR551A,CCDC3,MIR301B,MIR922,TRIM3,MIR30E,MIR625,RAN,MIR944,CUL3,MIR100,MIR24-2,EDC3,MIR29A,SRSF4,MIR874,EXOSC3,MIR542,IL23A,MIR549A,VEGFA,MIR652,NUDT16,MIR181C,MIR298,BMPR1A,MIR455,MIR194-2,EIF3E,MIR532,PPM1B,MIRLET7I,MECP2,MIR137,MIR769,ALKBH4,MIR653,MIR592,MALSU1,MIR129-2,FBXW7,MIR616,NKX3-1,NFKBIL1,NOG,MIR208B,FCGR2B,HDAC6,MACROH2A2,MIR924,MIR599,ACVR1B,TMBIM6,PCGF3,MIR23B,MIR205,ELOC,ASB1,CNOT6L,HNRNPD,TNRC6C,TUSC2,SERPINB1,EIF4A3,MIR920,PNRC1,MIR24-1,MIR101-1,SMAD3,MIR363,VSIR,MIR378A,TBK1,MIR632,MIR32,SFTPD,H2AZ2,RPS13,MIR183,H2AC1,MIR373,MIR222,CD2AP,MIR181D,NUDT12,MIR1180,MRPL13,MIR802,PABPC1,MIR937,ARG2,EIF2S1,MIR16-1,NFKB1,MIR141,LRIF1,TERT,MIR491,RBM42,PML,IGF2BP1,MIR7-1,MRTO4,H2AC25,PPARA,MIR607,DAPK3,MIR10A,MIR130B,PRNP,MIR449A,MIR589,LMNB1,LDLR,CD274,FOXP3,MIR1224,MIR885,CBX3,MIR186,PPP2CB,MORC2,MIR107,PYDC2,BAHD1,LSM5,CHMP1A,ERP29,TP53INP1,MIR379,EIF4E,IL6,MIR1-2,MIR633,CSK,MIR185,PCBP4,IL12B,MACIR,FOXP1,THRAP3,MIR190A,MIR223,IFNA2,MIR30B,MIR21,MIR96,INHA,MIR519D,MIR648,MIR375,CPNE1,ANAPC2,SYNCRIP,SMG8,MIR148A,RGCC,MIR580,TIA1,MIR383,ABCC2,MIR651,MIR330,MIR548C,MIR196B,MIRLET7D,MIR33B,MIR887,SRSF10,MIR197,DXO,MIR454,MIR210,UCN,MIR129-1,ANXA4,MIR593,CD36,MIR423,MIR577,MIR204,NMI,PC,SIN3A,MIR211,MIR595,MIR9-3,SELENOS,LSM4,MIR99A,PRMT5,RNF128,MIR92B,EXOSC8,TLR6,H2AC6,AKT1,MIR569,MIR938,MIR136,TGFB3,MIR374A,LMNA,MIR182,MIR1271,CLP1,MIR578,PPP3CA,H2AC7,ANXA7,TSNAX,INPP5E,MIR345,MIR877,CTNNB1,TNFAIP3,BAK1,MIR1227,GSTP1,MIR675,MIR331,CALR,MIR639,SIRT7,SKIC8,IGF1,MIR604,PTRH2,MIR384,PDCD10,CNOT2,PPP1R11,MAGOH,MIR497,CRKL,MIR492,PHF1,PAIP2,MIR130A,MIR221,MIR155,MIRLET7B,EIF2AK2,MIR206,MIR643,H2AC4,MIR377,CREBZF,RPL13A,MIR631,MIR320A,SNX12,MIR1251,MIR448,DEFB114,MIR10B,CD34,SMCHD1,MIR450B,MIR125A,MIR573,BST2,ACP5,MIR187,MIR500A,TCEAL1,POLE3,MIR586,APLNR,TLR4,DDIT3,TRIM27,KLF4,ENC1,SMG9,MIR590,MIR147A,PTPN11,PIWIL4,MIR155HG,FGFR1,MIR340,CNOT8,MIR99B,MIR26B,SAP18,NCBP2,DDX5,MIR34A,MIR609,IL13,ZC3H7A,MIR770,MIR216A,MIR1-1,IDO1,TP53,MIR583,MAEL,HENMT1,MIR133B,MIR671,MDM2,CXCL8,MIR188,MIR626,PTGER4,MIR30A,RBM15B,PPARG,MIR503,MIR212,MIR193B,SUV39H1,MIR711,GPNMB,MIR218-2,MIR106A,SESN2,PGR,HOMER3,HELLS,KLHL22,TSPO,UFD1,BTG2,MIR193A,DCP2,LHX2,MIR1262,EZH1,MIR554,CHRNA7,MIR198,UPF3B,DROSHA,MIR1249,EZH2,RPS26,MIR195,YTHDF2,PIWIL1,IFRD2,MIRLET7G,MIR422A,MIR934,GAPDH,MKKS,CNOT7,MIR28,LSM6,RNF139,MIR335,RAD21,MIR638,AGER,MIR23A,HRAS,PYCARD,MIR361,MIR628,MIR875,MIR98,EMILIN1,ITGB8,HINFP,MIR649,MIR1296,BCL6,EPHA2,MIR615,HFE,RGS2,MIR495,HMGB1,ETF1,PDE12,TRIM6,RPS3,NMBR,MSX1,CBX5,MIR145,CX3CR1,MIR191,MIR624,MIR1298,CX3CL1,MIR640,IL10,ROCK2,H2AZ1,MUL1,XCL1,MIR567,MIR611,MIR636,TWSG1,DDRGK1,SHMT1,ADIPOQ,TNF,MIR505,MIR9-2,MIR657,PDCD1LG2,MIR581,MIR552,MIR1277,CASC3,CLDN3,MIRLET7C,F2,XAF1,EIF4E2,NLRP3,PAIP2B,MIR764,PPM1D,GJA1,DIS3L,MIR502,H2AB1,MIR214,MIR17,MIR424,TYMS,MIR301A,RB1,ADNP,MIR338,H2AX,MIR105-1,CDKN1A,MIR16-2,SDR16C5,INPPL1,LSM14A,SRSF12,H2AC13,MIR1225,MIR557,SMAD5,BTN2A2,HEY2,EED,MIR132,IL12A,MOV10,SNIP1,CDK1,APLN,RPS6KA4,MIR194-1,LILRB1,MIR105-2,MIF,MIR190B,CCL3,CD83,MIR556,DAPK1,MIR490,AGO1,CRYAB,TDRD7,MIR142,MYC,MIR184,MIR484,MIR761,MIR553,MIR302B,SFRP1,MIR126,EPHA4,MIR200A,MIR605,MIR942,MIR216B,MIR3173,WWP2,MIR7-2,MIR106B,PSEN1,MIR146A,ARB2A,LILRB4,DGCR8,CD46,MIR149,MIR324,SMAD2,MIR342,NPTN,BRCA1,IL4,MIR504,MIR31,MIR662,MIR208A,ZMPSTE24,IL20RB,SOCS5,MIR150,MEF2C,ING2,MIR452,CD28,MIR760,SMG5,FURIN,RC3H2,MIR876,MIR101-2,CHID1,TYROBP,IFNB1,MIR661,CPTP,MBD3,MIR1226,HAND2,DDX4,MIR940,SRSF7,MIR147B,PIWIL2,MIR152,CCR7,DHX9,MIR600,DYRK1A,MIR25,MIR367,TRIM37,MIR517B,PTPN22,MIR30D,OTUD7B,LSM2,MIR9-1,MIR612,TGFB2,RLIM,MIR370,CRYBA1,MIR144,MIR192,LRP3,MIR597,NOTCH2,MIR346,MIR449B,PYM1,BANF1,PICALM,CNOT6,MIR215,MIR489,ZCCHC7,DICER1,MIR429,SOX9,NDFIP1,MIR656,IL1R2,MIR551B,GHRL,MIR20A,CIRBP,CPEB1,EXOSC4,CSNK2A1,MIR488,MIR558,OAS1,MIR936,CCR1,HDAC5,MIR511,MIR1260B,MIR339,XPO5,PELO,MIR708,MACROH2A1,MIR425,ATP2B4,MIR200C,CD200R1,SMAD1,MIR29C,NLRP6,EIF4EBP2,TSN |
| 2.439e-25 | -56.67 | bile_duct | COSMIC cancer mutations | bile_duct | 15095 | 4515 | 16828 | 4835 |
RTN4,GLRX5,GNAZ,SIAE,ISX,GAMT,ARG2,DNAJB9,RNF144B,PABPC1,GNG12,NTRK2,APOBEC3G,CNRIP1,FKRP,LPAR2,OR10A4,ELMOD2,USP15,METAP2,MME,ZFAND2A,SEC22C,MUL1,SMG9,GNG10,CTXN1,MAPRE1,NRN1,RORB,CKS2,ABHD5,CXCL13,EPHX1,MOXD1,RPA3,SIT1,FDFT1,NEGR1,GFPT1,SDHB,ATG4C,FRRS1,SNRNP48,CENPW,RWDD3,TXNDC12,UAP1,THAP7,PTAR1,MGAT5B,CRLF3,UCN,INO80E,DEPDC1B,RLIM,PTEN,ADAM21,CLDN3,USP8,TMEM147,COX8A,LGALS8,DHX38,GPR171,PTK7,PGRMC1,METTL15,NEUROD2,RPL27A,CBLN2,NUDT12,TYW5,JAGN1,SNAP29,NDUFAB1,HTRA2,THBD,OR4D6,BCL7C,IL1A,CINP,FBXW11,PPFIA2,CNDP2,FBXO44,DKC1,ARPC3,HR,LRRC3,DNTTIP1,AGPAT5,PLD3,PCYOX1L,CREG2,CTSC,NDUFS6,TMEM126B,PIK3R2,PDE1B,DDX23,PCNA,SPRED2,CDAN1,OPRM1,FZD3,CD247,RHOBTB1,IKZF5,HNRNPA0,CHST2,NXT2,RPS6KA4,GANAB,TSPAN18,XCL1,BBS5,ZNF664,MAT2B,MLC1,OCRL,DDX46,PDHB,CCDC134,SLC30A7,TCF19,SLC6A6,GPX1,TRIM15,RELL2,GRAP2,RAB27A,RPS7,NPPC,PSMD4,DHX15,OVOL1,RHEB,FBXL14,SLC11A2,PPP2R5E,SH2D1A,NPSR1,LMAN1,HSPA13,ANKRD34B,LSM10,LRRTM3,DAAM1,MRPL11,SCLT1,PMP22,SERPINA1,OR2Y1,STX11,LARP4B,TMEM179B,BFAR,TOMM22,ST6GAL1,CSGALNACT2,CSTF3,HENMT1,RPL7L1,PRR3,IL22,PCDH17,EPCAM,SAV1,TAGLN3,STAT2,SRSF7,UBA3,CBLL1,TOR3A,GLRX,TMEM117,MRPL34,NDUFB6,CYP21A2,GNAO1,NCDN,FASTKD5,CST11,SFXN2,SNX22,GNPDA1,KCNJ3,COMMD6,B3GALT1,AFAP1L2,TMEM30A,UBL3,IMP3,IRAK4,SHISAL2B,SCGB1D1,NLRP3,ILDR1,CCS,RASD1,OLFM3,SCG3,BMPR2,COMMD3,PPP1R1B,RND2,IER2,CHPF2,NDUFAF3,ZMYM3,CRIP1,PSMB1,HERC4,DKK1,NR2F6,ASNSD1,CNTN2,RBM22,RRM1,RPS16,KRAS,KDELR1,TOM1L1,ZNF365,BAG3,ILF2,ORC5,OXSR1,OXTR,KCNC1,SLC38A7,PGGT1B,CHIC2,CHCHD4,LAPTM4A,FBXL19,MRGPRX3,SUFU,MTA2,CCDC86,RAPGEF5,DBT,ELOVL7,TPD52,DSTN,DAPK3,RPS27A,PCDHB13,SLC16A1,OR13C8,TMEM101,NUF2,HINT2,MRPL18,FGFBP1,MFSD5,PSORS1C2,POP5,CHAC2,G3BP1,METTL21A,POLR1B,CER1,CHCHD6,SIAH2,UPK1A,HOXC4,RFXAP,EPS8,BIRC2,MTM1,FCGR2B,IFIH1,NUDT7,UMPS,CD1C,SS18,MRPL22,CDCA7L,CEP19,CHMP4C,PDAP1,SOX14,CX3CR1,SLCO2B1,IGF1R,UBP1,MAVS,KLHL22,NR2E1,DROSHA,ORC6,FLOT1,THOC2,STARD4,FAM177A1,DCTD,SCNM1,MCM4,CBR3,SEPHS2,CLEC2B,ADD1,LANCL2,APOBEC3H,GLRX2,ASB7,PRKACB,FEN1,VDAC1,CLPB,KLF1,ODAM,CNOT2,OTOS,CRHBP,ZNF326,MYBL2,PLEKHO1,GSTM5,ERAS,DNAJC19,VGLL4,SCML2,CLDN12,PKP4,GPR176,ELF5,CHKB,CCNY,PEA15,RNF8,EP300,ADAMTS10,COPS5,STAT5A,OTX2,MAGEH1,EIF4A2,PRDM4,FEZ1,FPGT,LRRC3B,PLCB2,MAP2K1,APOBEC3F,HSD17B6,TMEM167B,PTPN4,CHRNB2,GPX7,OR10P1,RIT1,SOSTDC1,MORC2,ELOVL1,SSR2,TPM3,SNRPB,EFNA3,AR,IFI6,PPM1K,OR8B12,LLPH,GSTP1,CCL2,RNASE1,TMEM45A,FAM43A,NLRP9,LAMP2,TNFRSF1B,CDNF,TGFBR2,CEBPG,USP3,CAPN1,METTL22,CYP2C8,ASZ1,SEMA4C,SLC2A3,FBXO7,RABGGTB,SPIN3,CLLU1,RPL23,CTTN,STOM,HP,CLEC18A,AQP2,SMAD1,ZNRF1,CHST13,FKBP8,GABPA,KLHL24,PPP2CB,RCL1,SF3B5,PPAN,IL2RA,TMEM70,MPDU1,VAMP8,TTL,PMM2,PRMT6,PRSS12,PPP3R2,TIMP3,CLDN9,SYNCRIP,TRMT112,SLC35F2,SLC16A10,VGLL2,DIO1,MTF1,RNF148,PRICKLE2,MSTN,RPL27,PPP1R1A,SPSB3,TOR1B,FAM83C,LTA,MRPS9,ABCG2,IFNB1,UBL5,BTN2A2,CSH1,POLB,MNS1,UBASH3B,POLA2,SEMG2,CCNH,KIAA0513,SERPINB1,UBLCP1,SRSF2,GSTA1,TRAK2,AVPR1B,ST7,TEX264,SNRK,FAM181B,NKIRAS2,ACVR1C,IL1R2,TMEM41A,KLF9,PIP4K2C,STUB1,BST2,PPP2R2C,STK4,SLC22A17,TNKS,ST8SIA5,CYP1A1,PLS3,HINT3,VRTN,SLC25A10,RPRD1A,GTF2H5,DDX50,TAF10,PRDX1,FAM53B,TUSC1,NFKBIA,NPW,PREB,ATG7,TRIM68,LRRC8B,ETF1,KLF4,COPS7B,DENND2D,OR10A6,OR4D2,RNF34,ACBD6,RFC3,SLC7A8,FBXO22,GPM6B,REG1B,ACP5,SERPINC1,HLF,TMEM59L,EGFL7,ATP6V1A,GTDC1,UBIAD1,LRRC61,TSNAX,POLR2B,PARL,DHRS13,TM4SF19,CRAT,NOTCH2,NAPA,PTPN11,SOBP,TMOD2,GNPDA2,CCR1,REN,ASTN1,SOD1,ATXN10,NCBP2,TBC1D13,SMPD2,DTWD1,AVL9,DECR2,TP53INP1,IQCK,FAF1,VEGFA,DDRGK1,RPL32,PSMA1,HDHD3,SHOC2,HARBI1,TMED5,LTB,TCEAL1,PFDN2,USP16,CLCN6,AK3,HMGCS1,SLC25A12,VPS26A,CMTM6,EEF1E1,TMEM50A,SMG8,MYC,LILRB4,CD40LG,FEM1A,SHISA2,KCTD10,MAB21L1,RAB35,PPP1R8,MKLN1,CCL28,RPS9,TIRAP,GEMIN8,MYL6,SEC23A,TUSC2,OR5V1,PSMG3,GPR173,TOP2B,CALML5,VAPB,PNMA1,SP2,HEBP2,SLC6A3,CASC3,TCF21,AKAP1,CLEC1A,DNAJC24,PARM1,PSMA6,PCSK9,KBTBD3,AGR2,CACNB3,TTC23,PCBD1,NLGN1,MORF4L1,TMEM174,CPSF4,LCN8,AGA,CD63,VPS16,ACO2,CLN8,SYK,SLC25A26,TNFAIP8L3,SLC48A1,CDC42,DUSP10,BACE1,SLC38A1,PIWIL3,IL2RG,FTH1,SNX1,PSEN2,SLC35F1,CCM2,ALB,CYTH2,RNF11,SYNGR2,APOC4,TAF7,OR4S2,WDR82,TLR10,ZBTB25,CD28,NAB2,FXYD6,GNL1,ZNF473,SELL,KIAA1143,ATP1B3,GNB1L,PPY,CRYAB,ROMO1,LAMP3,MATR3,CHPF,REEP6,CNOT6,PPP1R3C,CRADD,KCNAB1,AGTRAP,SEMA5A,APBB3,MCMBP,TNFAIP1,TMEM11,KLHL3,CFL1,BRIX1,IRGQ,RNF40,RPS26,DDX1,KDELR2,DAP,DPM2,RNASE6,TP53I3,SLCO1B3,GOSR2,FGF23,CYP2R1,SLC25A39,PRR5L,CD14,G6PC3,RANBP6,ZC3H11A,CCL27,HTR1A,TMX2,SFRP1,ELF1,WSCD1,CD86,PNMA5,MANBAL,SLC2A8,PSENEN,ENO2,OXCT1,ZNF704,EXD2,KBTBD6,UBE2H,FARSA,ELOVL4,PAK6,CHMP2B,CSNK1E,SKA1,GRB10,ERVFRD-1,AKT3,MAN1A2,POLD4,CCDC92,RBP5,DNAJC4,EIF3D,OR5A2,ARMCX3,CUL3,COX16,FAS,ATF1,ABCB9,UBTD1,MAD2L2,TMPO,COX6A2,POLR3GL,RBBP4,TXNRD2,DNAJB4,C2CD2L,RAD21,RAP1B,SNX14,COQ10B,POLR2G,ACTR1A,LAT2,FITM1,CARHSP1,TIMM8A,NPC1L1,KLHL9,SDC2,ACVR1B,FAH,CTDSP2,RPL10A,ANAPC4,GDPD3,ARPP19,LRRC4B,TOMM40,GREM1,FABP4,COX4I1,MPHOSPH6,MAP1S,BHLHE40,PI16,MRPL53,HDAC3,RPL29,GLRA2,KLHL26,BET1L,WRAP53,MMD,GAS2,UCHL3,EEF1A1,TRAPPC4,PAAF1,TFPI,PRKCA,SURF6,BRD3,FAR2,TMEM108,DVL2,TESK1,TTC33,C2CD4C,OR2AT4,RPL39,ADM2,IZUMO4,AHCYL1,ALDH1A3,NPTX1,CLIC4,COX11,HNRNPH2,HMOX2,EXTL2,RCCD1,SLC20A1,ALPL,ADIPOR2,LAP3,C2CD2,EFHD1,SAMM50,KCNJ8,ENC1,PYGB,HOMER1,PDE8A,PSMB9,FOXP1,SLC4A10,CRYM,SAMHD1,TPH2,SPRYD4,KCNS1,FKBP1A,SRXN1,DNAJC30,P2RY12,EHD3,MRPS18B,ST3GAL4,ZMAT2,NT5C2,DOLK,RPL9,TST,DGCR8,RNF5,API5,AUH,TTC8,TFRC,ZNF267,IDE,ZNF177,ZNF652,HSD17B11,C1QTNF1,HMGA1,OR1S1,SH2D5,UTP6,MND1,TSPAN11,GGPS1,IPCEF1,PABPC1L,LSM2,TMBIM6,CCT8,DNAJC7,CD83,RPL12,KCTD12,UQCRQ,SOD3,DUSP22,GFOD2,ADAMTS20,YWHAH,MRPL49,GABRB3,FAM187B,PLCL1,ICAM1,MTMR2,AP2A1,APTX,HRH2,SPINT2,ZNF688,BCL2A1,TMEM45B,TFDP2,ZNF22,C1D,ACTR3B,MIF,RBM15B,ZNF189,EEF1B2,LRRC8D,ETFB,VIP,NTNG2,FBXO11,RBBP9,SPSB1,WNT10B,DGCR6L,POLR2D,SNX12,CNTFR,KRT222,SMNDC1,PDP2,NEURL2,NDP,TMEM42,SNX33,USP13,SDCBP,FGF3,DRG1,ERLEC1,CEP85,SRPRB,MYL12B,GINS3,ENHO,ATP6V1E2,ZHX3,IL7,SRSF4,NECAP2,SH3BGRL,EXOSC3,PID1,GPR146,OPTN,KCTD11,CLEC7A,APPBP2,ARPC2,FOXJ3,ORMDL3,RAD23B,USP30,UFM1,HAX1,LRRC20,EGR2,OR1F1,RPS3,CHN2,TMEM60,HBEGF,CALU,AIF1,YIF1A,OR10Q1,CA8,NMBR,LGALS3,MAP4,LUC7L3,HHIP,RAB3A,DDIT4,SMYD3,FAM91A1,LCN12,CTNND1,OMG,GPD2,CELA3B,FBXL7,LBR,CYP11B2,PHF21A,COX5A,THNSL1,SLC1A2,RHBDL3,TRMT61A,CAMP,DCAF4L2,RPRD1B,TSPO,LYPLA2,POP7,STYK1,RNF181,ELOVL6,ALOX5AP,TFPT,NUP35,ZNHIT1,MECP2,PRDX4,SLC25A14,RASL11A,CLSTN3,TBC1D19,RGS6,CSTA,OLFM2,ENO1,GNPTG,CHST7,SERPIND1,ORAI2,CRYL1,RPL24,PPP2R5A,VASH1,TLR7,GAPT,PTGES,ACADS,RNF128,SYBU,EXOC5,SERPINB6,NAA15,WDR55,RALA,FTHL17,F11R,G6PD,ADK,OR5B3,BRMS1L,HCST,FBXO34,PAPOLA,DHRS1,CHORDC1,ZBTB16,ANAPC16,TLR1,CAPG,OGDHL,SAR1B,IL12A,RHAG,GSTM3,SYNDIG1,TSEN34,FTSJ3,SLC25A46,TBC1D17,HEXIM2,TMED4,HSD17B1,PTRHD1,TOX,IRF8,RWDD4,KPNA6,CYB561,BET1,FCER1G,TP53,NFKBIL1,CRELD1,INMT,PRDX6,TAX1BP1,AP2M1,KIN,STX7,SENP8,MGST2,GADD45B,HBA1,OSGIN2,MZT2B,LIMS2,NECAP1,GPC4,PKIA,TRIM35,TRAFD1,PPM1B,GABARAPL2,PML,DNASE1L1,PSMA4,OR10A7,SERTAD3,MT3,EIF1B,GABPB1,ARF4,ZNF790,TAX1BP3,RDH12,CALY,RPS12,CYB5D2,TXN,MAF1,DUSP6,MTHFS,PPIF,SETD7,ZBED3,DAG1,BMPR1A,FAF2,RHCG,ARHGAP21,SCG2,AP3S2,MRPL47,TMEM33,S100PBP,MPHOSPH10,KLF10,RPGRIP1L,OR2W1,CCND1,WFDC13,ACOT13,TMED3,FBXO9,COX7A1,LCN6,SETD4,NDNF,ANP32B,CHST9,CPT2,NFYA,S100A10,FAM200A,STX8,DUSP1,TGFB1I1,BATF,TOLLIP,PWP2,RAB3C,MTAP,CTSK,CACYBP,CETN3,URM1,CTSD,PGAP2,MRGPRX4,FABP5,AKR1A1,NOP58,SPATS2L,NFE2L1,RBCK1,MRPS25,PPIB,BPGM,CDKN3,CD164,OR52M1,NUP107,SCAMP2,SPEF1,SLC5A6,PRKD3,CYP4F8,NLGN2,DEK,DEGS1,CRYBA2,CCDC42,NPTN,FCAR,POU1F1,CYC1,PTDSS1,ID1,ENTPD4,SLC35A2,ARMC8,KIF2A,MIA2,BACH1,INPPL1,SIVA1,GFOD1,SNTA1,SNAPC1,GPR37L1,NDUFAF2,SOST,TCP11L1,SV2B,HPCA,OR2A2,EIF4EBP2,TSSC4,ALDH1L1,MAK16,POLL,NONO,SPRED1,H19,TAPBPL,ETV6,RRAGA,SIRT7,FYTTD1,IQSEC1,NOL4,MMACHC,TRAF7,DUOXA2,MTMR12,RAP2B,ABHD16B,TNFAIP3,RAB8B,CTNNB1,CYP2D6,SOCS2,INTS12,SFTPD,CLEC12B,SNRPD2,ADCY3,DCAF5,ESR2,CDK6,CWF19L1,ZNF174,USP38,SLPI,USP39,CERK,ENPEP,NAB1,SYNGR1,RTP4,LSM6,PRKX,FGF13,PROX1,OR6M1,NUDT16,B4GALT6,KCNA2,HSPB1,LHFPL1,HADHA,LEAP2,DHX16,SOX21,TRA2B,SERPINH1,RPL37A,HSPE1,CLDN14,ZKSCAN1,SIPA1L1,STAMBPL1,PGBD2,CDC37L1,SNAI3,PELI3,KRR1,NLE1,RPRML,MSX2,WNT7A,LEPR,STX17,EIF1AD,ISYNA1,NDUFB8,APH1A,CXCL1,PDIA3,FRA10AC1,XPOT,ACAA2,UCKL1,RAP1A,RABAC1,WWP2,FBXO30,TIGD7,CD2,POLR2I,ST13,LPXN,RASGRP2,IL34,DFFA,KCND2,CCL21,NDUFA5,TRMT6,PTCRA,NEDD8,CXCR1,HBB,FGF17,RBM23,TMED1,ADAT1,OCEL1,HEXA,BRI3,OXNAD1,NQO1,IPP,TBCE,SPATA2L,LMBR1L,IGFBP4,NPVF,AKR1C2,OPA3,TAC1,KIF1C,CHRNA7,GAS8,CDKL2,CD3G,PAOX,BRMS1,ZMYND11,SLC7A4,ZNF513,GPR162,APOBEC3C,RNF187,XPO5,INTS10,SURF4,TF,CREB3,RNF103,THRAP3,EEF2,GJA10,SLC25A32,EFHC1,XPO1,EXOC2,DNAL4,FATE1,ATP2C1,RC3H2,RANGRF,ABCC5,THOC1,GSK3A,PRCC,PFDN6,LDHA,NUBP2,UBXN10,PCDHA5,SLC20A2,IL23A,PSMD6,DHX9,FURIN,SLC39A9,ZSCAN1,OR51S1,EIF4EBP3,WDR37,CREBL2,TXNIP,AQP4,CCL25,GNMT,FUT8,WBP2,GTF2A1,UTS2R,NEK7,LASP1,PHKG1,SPOCK1,OSR2,CXXC5,ENDOD1,CIRBP,EIF2B5,SH3GLB2,GALE,IMPACT,CD58,AGER,FKBP14,IDH2,RAB18,ZNF593,ARMCX5,PRPF4,AGK,ANAPC2,FBXO32,ENPP4,CCT5,MCOLN1,PSMB5,SORD,SBK2,CCDC127,FAM89B,PEX3,RCVRN,PPP3CA,CRYGB,KCNJ11,CD200R1,CAMK2N1,HCRT,FGFR1,SHC1,PYGM,OR4K1,CCDC47,TTC4,SCFD1,GHITM,RPL15,TUBG1,CIB3,TACR3,PRMT2,CAMK2G,BUD31,SRP54,TMX4,SPTAN1,SLC35E3,RNASET2,NPY2R,LRP12,FAM199X,RABL2B,NIPA2,PAEP,CLDN11,TRAPPC1,HEY2,PCDHB8,RBM17,ZDHHC14,ADRB1,PKNOX1,FRMD8,RFX4,SPR,ARFIP1,GALNT12,PPARG,ACTA2,TRIM21,SIX5,ARMCX2,RMND5B,RBBP7,SLC25A21,PGS1,NFIL3,TRIM37,HECW1,PTPN1,HNRNPC,SETD5,CDCA3,RAB3B,SMAP2,KTI12,NDST1,TNFAIP8L2,DEFB116,DHRS3,TBC1D10C,MAGOH,CCL19,NKX3-2,GTF2E2,MLF1,LBH,JAK1,FGF1,HBE1,ABCB1,INO80C,AZGP1,PSME2,AZIN1,TSEN54,SERPINB10,TMEM215,FBXO42,ZNF24,LYG2,MFSD6L,GPBP1L1,MX2,ZCCHC10,SYN3,AAMP,FZD4,MEST,WDR77,MTPN,ATP6V1G1,TMIGD1,DNAJC5,MYH2,ALKBH4,HEBP1,PACSIN3,SLC7A9,PGK1,ROPN1B,VRK1,MMP9,BTF3,S100A6,DYNC1I2,CYP27A1,UBAP1,ZYX,CDC73,LHX2,KIT,RS1,LSM3,OR4D9,AFTPH,JOSD1,P4HA2,SUPT7L,KBTBD2,GSTO2,ATF4,GNG7,CTNNBIP1,RARRES2,KPNA1,PIWIL4,CSNK2A1,ID4,ZNF319,SEC14L1,APOBEC3A,ZNF397,XAGE5,SLAMF9,ZMYND19,TAAR1,CCR6,ATPAF2,KIAA0232,CLU,LMO4,GLUL,CNIH4,CDK5R1,NRP1,NCKAP1,FGFR1OP2,GABARAP,PRPSAP1,ELMO1,GRPEL1,TCP11L2,LTBR,GAL3ST1,OR4D11,CASK,OR8B8,IRF1,P2RY1,STRBP,ING1,NAIF1,TRIM23,NHP2,CCT2,UBE2D3,ATP6V0E1,ARMCX1,UBE2A,RMND1,MIOS,FAM78A,PPP1R2,IL15RA,OSM,SLC38A9,MRPL24,MRPL50,ZNF304,SNAPIN,SLC30A5,KLK3,ENY2,RAG1,IMMP2L,DHRS4,SLC35A1,CHDH,GNRH2,CYP39A1,HSD11B1,MYL12A,SWAP70,FAM8A1,EIF4H,ITK,NCR3,TLR3,GPAA1,JAKMIP1,SENP5,IDH3B,CYP11B1,CTNNBL1,GRM2,COMTD1,FNDC8,APEH,FGD2,DLX1,AKT1,L1CAM,FIBIN,TLR9,CCNI,PPIL4,RAB11A,CDO1,CRABP2,PRRC2A,DPP10,SF3B4,IL20RB,DKK3,RND3,CNP,NUDT3,B9D1,LYAR,GNRHR2,TOM1L2,PFDN5,EXOC8,UST,MRPL13,EHBP1,MDM2,MGP,TMEM156,GSTO1,GALNT1,AK2,SOCS5,PSMA3,CCDC69,MRPL23,GDI2,GFM2,E2F6,ZMPSTE24,EXOSC1,EFCAB7,GPR89A,SDR42E1,PDIA6,UBR7,CD99L2,SNRNP27,PRIM2,TRIM32,KLHDC8B,RNF141,ARHGAP1,DOK4,PLA2G5,KLK9,UGCG,MEAF6,LYPLA1,RPS14,LIG3,SLC17A5,ZNF671,SLC25A31,POLR3H,C1QC,TRIM3,TMUB1,ATP6V0B,TMEM219,EDF1,ZNF207,CLDN4,LAMB2,SLC13A5,RAB3D,SDF2L1,RUVBL1,CXCL3,GTF2B,NKIRAS1,OAS1,GIT2,ACAT1,ZNF287,TMEM184B,KDM4B,ACBD7,FAM98A,CDC42SE2,RPLP2,TRIM54,HTR1F,OR4Q3,PDCD4,GPAM,LDOC1,CREBBP,PRPF19,RDH10,TGIF2,GREM2,POPDC2,GPX6,CTDSP1,CCNB1,CRYBB2,NDUFAF4,AKAP14,TFCP2,CLDN1,ABHD6,METTL2A,CRTAP,UHMK1,ERH,ALKBH5,ADIPOQ,ANKRA2,MAP3K11,MBL2,TOR2A,PTS,JPH4,AMIGO1,GNG2,EDEM1,METTL14,VAMP5,CSGALNACT1,R3HCC1,SAT1,COL1A2,RMI2,SMU1,SLC35D1,TMEM123,DSTYK,AIF1L,ZC3H7A,ZBTB5,IPO8,TMSB10,CIDEB,ARMC7,ATAT1,HSP90AB1,POLE4,GPHN,ISG20L2,RER1,FCN2,RGS7BP,CDKN2AIP,SFRP4,ATG4A,SYP,ZNF862,CSRNP1,MRPS23,FUNDC2,CHGA,PAPSS2,TCF23,HTR5A,TMX3,EIF2B3,TOM1,BCL7B,GPR65,SEC61B,MYO6,NDUFS8,CYP2C18,F9,PGPEP1,NKX3-1,GCNT3,OPRK1,TMEM144,TOP1,NRSN2,GPR137,SNX17,BCS1L,APOO,ELP3,YAF2,ACSL4,MRFAP1L1,TGFB3,CIB2,MTRF1,ZNF592,EED,MRPS16,ABHD14B,GPX3,PROS1,TMEM204,B9D2,EWSR1,VMP1,SLC19A2,CBR4,HSPA8,EMP3,OSTM1,CHMP2A,CCDC25,TES,BECN1,LMNB1,GMPPB,CALHM2,ADO,RPLP0,UBE2V2,IL10,FUT9,PHYH,RTKN,NTN4,ITGA6,CSNK1A1,COMMD8,TFE3,IFNA10,DEFB114,MT1M,EFNB1,PREPL,SH3GLB1,THTPA,OLFML3,TSPO2,GOLGA7B,TMSB4X,TRIM5,EIF4E,LHFPL4,COX4I2,CDKN2C,SNAPC3,BLOC1S2,SNCG,IGBP1,AKAP12,SSU72,DDX39A,RAB40AL,BCAP29,ZBTB17,FABP7,CD274,B3GALNT1,CREB3L4,EIF3K,SPECC1L,NAT2,KHDC1,RINT1,BZW2,TSPAN5,OR10G9,ZNF501,CEP97,ST3GAL5,SLC32A1,PARP11,LRP6,PYROXD2,MRPS21,STK24,LCA5,RAC2,PRKAB1,DPEP1,UQCRH,MTHFD2L,CD36,IRF3,KLC2,PAX9,STXBP1,CSNK1A1L,SOX2,ST3GAL1,DERL1,IL18,DNAJC3,RNASEH1,TMED7,KLK6,FKTN,SLC41A3,SERINC3,TSN,STOML3,STAU1,BRCA1,PCDHB1,ABHD4,RBM7,TRAF2,KCNK13,CDK4,NPR2,CNNM4,NR1I2,DPY30,RGS2,STMN2,NME1,DUSP19,ADPRH,PDHA1,MBD5,NOS1AP,BCL10,KCNMA1,ZBTB45,ABHD13,HRH3,RAB1B,RPAP2,OR5L1,INHA,RGS5,ACTL6B,FAM168A,LY6G5C,UBE2D1,SNIP1,SLC4A8,LDHAL6B,CCDC65,HMBS,CD2BP2,TDRD7,RBMX2,NDE1,AMY2B,OTUD7B,PPFIA3,SDHAF2,MED11,CLIC2,ELSPBP1,ORAI3,STX18,SLITRK2,RBFOX2,FOXN2,CDKN1A,GK2,PGM2L1,ROGDI,SLC23A2,GYS1,AKIP1,SOS2,PIWIL2,UQCR11,GLT8D1,NGB,MOV10,TAF5L,PNPLA8,MYEF2,CDH8,CPSF2,PCGF3,GPX5,GDE1,TCEAL7,TMEM14A,LIX1,KLK5,CAB39,DDX4,MRGPRX2,GRIA2,LRRC24,TOP3B,TEX12,HIGD2A,TMEM91,ZCCHC9,SLC43A2,RAB9B,AMT,KCNIP3,INPP4A,ARCN1,EZH2,STAT6,OR10G7,SNX24,ACADSB,ISG15,FN3KRP,WIF1,DYRK1B,PHYHIP,CTNNA1,RAB2A,WDR44,GPIHBP1,TRAPPC6B,CCNF,VAMP2,BEND5,CMPK1,SNRPA,B4GALT3,PDYN,ZFP1,CRBN,CD226,VPS33A,SACM1L,CAV2,PSRC1,FBXO25,IFI35,CSTF2T,C1QL1,RAB37,SLC6A11,FOLR1,AP1AR,PCDH19,PNP,RAB5C,STK38,TIMM10,SLC25A4,MRTO4,PTHLH,SMAD3,PPP2R1A,EIF4B,IL6ST,TMEM59,LYNX1,RPL23A,PLEKHJ1,MLF2,TIMP1,DERL2,TXNL1,GIMAP2,GNPNAT1,FERMT2,EIF3J,TOMM40L,UTP23,CHI3L1,RNASEL,SPTBN1,RAB33A,CRYGD,FAM107A,RNF167,PPDPF,TNFSF18,DNAJC8,CMAS,RAB23,SFT2D2,PTGER1,OPHN1,SUMO3,OGG1,ZNF687,CCR3,TMEM50B,IFNG,JUN,CD47,HIRA,S100A8,CBLN4,RHOJ,WWP1,STX6,OR2A25,FANCG,PLA2G15,HNRNPA2B1,GGCT,RCBTB1,ATP6V1C1,YPEL5,PPID,TPPP,RFTN2,RB1CC1,CAPZA2,SLC35E1,CCL8,OAT,MRPS28,RIOK2,POMP,OS9,RPL26,EGLN3,CLDN22,DYRK2,FOS,LHFPL2,ACAP2,SCD5,NFKB1,PRKAG1,PAFAH1B3,HNRNPK,BNIP3L,CLDN8,CXCL14,ADAMTS1,TUSC3,RPL6,SPRR1B,CYB561D2,GMPPA,MT2A,PPP1R16A,PXMP2,ATP1A2,DDX42,SLC7A14,KCNH1,CCL17,KIAA1191,GTF2F2,PAFAH1B2,HSPA14,CXCR4,NPY5R,POLR3B,BRD9,HAND2,PGR,RPP25,RBM12,RAN,GLIPR1,SQSTM1,FMO2,TMEM177,BICD2,CREB1,SERPINA5,KIAA0408,RNF122,SYNJ2BP,ACP6,TMEM164,APLN,CRYBB3,OR4F6,TAS2R5,FOXS1,PTRH2,ACTR2,SRP14,NUS1,TMEM106C,KRT7,PLEKHA8,MANSC1,GJB2,WDR3,ZNF609,TMCC2,SLCO1A2,KCNK10,PPP1CB,TRAM2,MPV17,CHST1,EHD1,RABL3,UPF3B,ISCA2,ZNF576,GCA,KLHL15,RFXANK,TRAM1L1,PAPOLB,PLAGL1,SESN2,ZNHIT6,PLCB1,GPR17,GPC1,PRSS23,FRZB,SPP1,TSR2,CHRM3,ARL2BP,ING2,PSMB7,TNFAIP6,FBXW7,DMTF1,PLG,DLK2,CDK12,LIAS,CITED1,TXNDC17,ARL4D,CPLX3,TNNI3K,NPY1R,GCLC,PSMD10,EPHA4,CTU1,KCNJ2,SLC25A1,HNRNPF,STAMBP,ZNF511,CEND1,EHD4,FAM81A,GRM1,PCGF6,OR4K2,KCNJ10,SHPRH,ADORA1,SLCO3A1,SPATA2,TAF1D,HOMER3,CXCR3,MAGEB10,AASDHPPT,RNF222,REEP4,TM4SF20,CCNA2,GJA1,MAGED2,SURF2,SLC29A1,TM4SF18,OR6X1,TNR,BOK,LSM14A,CAPN2,OR8H3,SLC8A1,ICAM2,ABHD8,STARD3NL,YWHAZ,CPLX2,PRND,HUWE1,ABHD10,CNTROB,FTSJ1,AKR1C1,MRPS11,RAB39B,CSNK1G3,SPEM1,CYP3A43,PDE4B,TTPAL,PMAIP1,CCIN,UBE2L3,EIF3G,MEPCE,TCEAL8,LXN,YIPF3,RPS2,B4GALT4,CAV1,NINJ1,ICOS,BLCAP,ITGB5,RGL2,TRIM34,NDUFC2,TRIM29,OIP5,CORO6,RB1,DPH5,PNMA3,DDAH1,GPR35,HFE,NDUFA1,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,NT5DC1,MRPS18C,TRIM36,PROK1,JAK2,PAQR3,CREBZF,PLSCR1,PTP4A3,DCAF12L2,COMMD9,CBLN1,STK3,HSPB2,LILRA2,TNKS2,LY6H,UBE2E2,FSTL1,RHOBTB3,HGS,POLR2L,POLDIP3,DPH3,CRISP1,ELK3,LRRC40,CD81,MT1E,COX6B2,RNF133,TMEM170A,PRKRA,TSPAN17,ZNF451,PRKCE,GNRH1,WDSUB1,DBR1,TAS2R13,KLHL1,FOXA3,CARTPT,SESTD1,ABHD12,BANF1,PARP2,NF2,RPL26L1,PHF13,CGGBP1,SUMO2,TFB1M,LZTFL1,SNRPB2,KLF3,CCR4,CHRAC1,GGH,TNF,PPAT,IL17F,NUDT9,CYGB,OLR1,SLC19A3,NDST3,FBXO8,PRL,MPPED2,CDC7,MRPS34,IGSF11,CYP2C9,DUSP21,ATAD1,TRIM45,MGAT4A,RBBP8,SGMS1,XRCC5,ACCS,TIMP4,SNRPG,ZDHHC4,WDR5B,CDC20,SEC13,IL2,NBN,VMAC,TNFAIP8L1,TBC1D25,AIPL1,PEX13,NHEJ1,WDR11,SLC35B3,FHOD3,TYROBP,CBX3,DR1,GTPBP8,HS2ST1,TRPC1,LYPD6,ELMO2,BCL9,ASPA,GABRA1,PRNP,CAND1,HSD17B10,TMEM89,MIS12,SNX10,CA2,USP6NL,MTDH,SGTA,TPPP3,ZNF263,SSX2IP,BCL6,E4F1,TMED9,GSTCD,DLST,GTF2F1,TMEM185A,PAIP2,NDUFS2,PIK3CA,IVNS1ABP,SNRNP40,FAM83B,JAKMIP2,CDH11,PSMC3,CPT1B,ZBTB39,RBM27,CNN3,ANKMY2,LY96,AP1S2,TMEM47,MAD2L1BP,AKR1B1,APEX2,ADORA3,SF3B1,TAB1,COCH,FEM1C,PIK3AP1,LST1,COX6C,PICALM,XAF1,VTA1,RPIA,CRTC2,TMEM38B,TSPAN15,NPM3,NUDT2,GH1,PEBP4,BAX,ATP1A3,PSD2,CIAO1,ATP8A1,KIF3C,GHRL,VPS18,SUCLG2,PDE7A,DUSP3,SCML1,ZFAND6,TAPT1,MED10,TYMS,NAA16,GJC1,RPS20,SLC12A2,RUNX1,YTHDF2,FAM161A,ANKRD6,SRFBP1,PFKFB2,ARHGAP12,EIF5B,ACER3,MREG,DIRAS2,RASSF8,KCTD17,CLEC6A,SSBP4,RBP2,TLCD1,AQP11,LMO2,FKBP1B,LCORL,EDA2R,OR13A1,PSEN1,MAGEC2,TRAPPC6A,MDC1,MTCH2,ITM2B,SP1,MGMT,TRAM1,TADA3,FUNDC1,AP1M1,ECHDC1,UBA52,IMPA2,SPRY1,RPS10,CLDND1,CCDC106,ETNK2,GIN1,TKTL1,RPL18,TRAF6,VPS72,KRIT1,ROCK2,KCND3,FUBP3,FXN,UPRT,SUPT3H,SGIP1,MRPS17,MECR,MRPL9,UBE2G2,FEM1B,TRIM26,IER3,NUCKS1,CENPL,KLRC2,TOX4,IFT172,TMBIM1,CYTH4,CPNE2,RAMP3,SLU7,FAM3C,PTP4A2,MFAP3L,IRF7,TMEM165,OR8B4,KLHL25,RPE,SULT1B1,CYBRD1,MACROD1,ADCK1,ZNF518B,FAM151B,FAM136A,SLC35E4,PRR13,SLC25A5,OAZ1,WSB1,LYZ,TOPORS,TANK,SYNGR3,BRAP,MPG,MBD3,CDC23,DMPK,OR5M9,HAUS2,RP9,ELFN2,GALC,LRRC8A,GNGT2,CNPY1,SSPN,NKAP,LBX1,RDH11,PIH1D1,KCTD3,ANXA4,IL18BP,RASL12,GALNT2,RRAGB,SNRPE,GRIK1,CMA1,DLGAP4,IGF1,CCR7,SNAP25,RXRG,GORASP2,THUMPD1,TTC9C,GMPS,OR1M1,RUSC2,CD9,GRPR,GADD45A,IGFBP3,DPEP3,TMEM183A,BTG3,THOC3,PIGA,GLOD4,MX1,BOLL,RBMS2,TGFB2,VPS54,SLC25A27,ZNF622,ATG9A,S100A11,SLC22A6,SPG21,TIA1,DDR1,SAP18,EXOC3,TMEM81,CAP2,PIAS1,PNPLA4,NPC2,TMEM115,PARD6A,LRRC28,TCEA2,HSPD1,EIF1AX,RNASEH2C,HSPA5,GNA11,SERTAD2,HSPB6,CRYBA1,MPV17L2,THAP8,WDR45,NRM,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,NR1I3,PAIP2B,LRP10,TRIM44,TMEM229B,HINFP,NUFIP2,GNB3,CCDC3,VAV2,BTG2,ITGB8,RNF10,GP9,OR51E2,POLE3,KRTAP8-1,APLNR,CYP4V2,SRI,NCAPG2,CNPY3,DTWD2,PSMD3,POLR1D,GPR160,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,TEX261,OR4D5,IL2RB,PTGFR,IP6K1,P2RY4,FBXW4,TAS2R7,ST3GAL2,CD209,STAR,TRIP4,RPL10,PDCL,SUPT5H,SLC25A24,GLCE,GK5,SSNA1,THAP1,FBXL4,CD34,CPXM1,PRCP,EID2B,TMEM100,DCTPP1,OR4A47,YPEL4,LDB2,RNASE9,GADD45G,RPA2,TMEM107,TRAF3IP3,PIWIL1,CCDC90B,SRPK2,TAB2,ARFGEF1,NOG,TLR8,PMPCA,TNFSF15,SLC6A2,CD40,AIP,CRY1,SIN3A,CDK7,PLAC1,PSMD7,SCAND1,RAB6A,CTTNBP2,FKBPL,RGN,PYCR2,ZNF428,PDE2A,TNFSF8,CDIPT,PSMB4,HERC3,SEMA3C,DOK6,LSM4,IRF9,HSD17B8,DDX39B,CGRRF1,NETO1,CDR2,PTGER2,C9orf72,NAA30,ZMAT3,BRS3,RSL24D1,TRAF1,CLK1,SKAP2,SERPINA3,RASSF4,KCTD20,UQCRC1,NOC4L,CRHR1,AKR1E2,OLA1,PRPS1,HAS3,TSPAN3,BAD,MGST3,RPL31,WTAP,SSBP2,PDCD10,GDAP1L1,LRRN4CL,OR6C4,RFX5,TRAPPC2L,MAT2A,NMRAL1,PHOSPHO2,TAF9,MEA1,HMGN4,SCHIP1,COX7B2,CMBL,CDKN1B,TEX19,ZNF655,TRIM62,GPR78,ZBTB6,PLEKHF1,AHSA1,KCTD16,SLC15A1,SIAH1,STRADB,LRP3,NCK1,ST8SIA4,TMEM220,TMEM168,CD200,TMEM176B,CEBPE,RPL22,DLG3,RHOU,ACSS2,DEFB1,IFRD1,MAP1LC3B,PDLIM3,PRSS37,ATF3,CTLA4,RBM5,RANBP1,POPDC3,RETSAT,SLC7A11,MET,FZD6,ADIPOR1,PRM1,GFM1,SSH3,HOXB8,CENPM,EMX2,SEC61G,PDE6A,IMP4,HELT,TIMMDC1,SERPINB9,MT1X,UBE2V1,SNX11,RPLP1,CYP26A1,GMNN,TMEM87A,RALB,NUDT1,ISG20,FKBP2,PRSS35,TBCEL,CCDC22,KDM1A,NDFIP1,PSMG2,ARL6IP5,ABHD2,CEP70,CTDSPL2,SNN,SNRPA1,BIRC5,MFSD3,LDB1,TRAPPC3,CSRNP3,NRGN,GMDS,WNT2,SAP30BP,HAPLN2,EDC3,AANAT,ANKH,YKT6,VPS26B,CAMKV,F2,ESYT1,ARL5B,MRGPRX1,LIPT2,HPCAL1,TRMT5,OR9I1,BCKDK,ZCRB1,MED4,CYB5B,NAP1L5,SEMA7A,NACC2,CHRM5,DRD3,EMILIN3,NAP1L3,CEACAM5,DIS3L,CA14,CEP57L1,OSBPL8,TACR1,ARHGAP19,THG1L,PDLIM4,GABBR1,ERCC3,TIMM13,XBP1,RPF2,TBC1D1,GPR34,CHTOP,SYPL1,ZNF343,EGR1,WBP11,ZNF436,STARD7,ACTL6A,ACP2,FOSL2,GNPAT,SETD3,GPR75,TMEM126A,ARHGAP15,RHOH,ERLIN2,HYAL2,UBE2S,NPBWR1,RPSA,PIK3CG,MAGEA4,STT3A,CCDC126,RRP7A,RBM3,RACGAP1,CORO1C,VSTM2L,FBXO31,MAP1B,CNOT8,PIGK,PELI1,NEU1,AMELX,VSTM4,PDCD1LG2,GLO1,RAB1A,WDR12,MLN,KLF12,ADD2,SOD2,PCP2,TCTA,TEF,ANKRD10,SCN2B,ALG5,DEXI,SUGP1,STARD5,FMO1,ABCC2,ACTR1B,STAP1,HTR2A,SMARCB1,GTF3C4,MMP20,PLCXD3,C1QL2,REG1A,OR4K13,DNM2,CLRN2,SRD5A3,DCAF16,TLR5,RFC4,LCN1,HS3ST3A1,TICAM1,GPM6A,PNPO,OR2D3,COTL1,SOX9,KCNG3,CHST10,GAB1,ITPRIPL2,AKT2,APEX1,PRSS1,PSMC5,ECD,CD59,ETFA,PRELID1,AQP3,DYNLRB2,CKS1B,HBP1,RPL4,RGL1,SUV39H1,DCTN3,LSM5,IRF2BPL,PRKCB,PABPC5,HCFC2,RWDD1,SLC25A3,COPE,RBM41,TPST1,IZUMO2,ZNF200,LCP1,AGGF1,HNRNPH3,GJB1,GCHFR,CSF2,PCYT1B,PRELP,KRT8,CHCHD2,SKP1,TTLL10,HDAC11,SIGLEC5,ATG16L1,DIRAS3,TP53TG5,PSMB10,CDK17,ART5,TMEM39A,CDKN2D,GPR37,ESD,ATP6V1D,VWF,CLP1,CLPX,OR5AN1,CFTR,ATG3,INA,VPS39,MYLIP,FAM174A,SART3,PTPRZ1,IFI16,PSMD1,BARX2,MPP1,RANBP10,SRM,MED27,ADH1B,BMPR1B,OR4M1,HS3ST1,TULP3,PCBP4,MLH3,APOBEC3B,BLVRA,PITPNA,RAB32,CRYBA4,CRYZ,FOXC2,RAB11B,ARL6,STX5,CCND3,CSRP1,IRF4,LEMD3,CMTM7,SPATA4,TBC1D16,SLC7A1,CA12,ADRB3,FMOD,SMG5,RNF139,PLP2,ABCF1,DUS4L,DYNLL1,LYPLAL1,HSDL2,OPRL1,CCL11,RXFP2,RAB9A,RPAP3,HINT1,TNPO2,THOC6,PYCR1,SLA2,IFNAR1,SDR16C5,MARCKSL1,PTPN5,RNF182,TIMM17A,SMAD9,RELL1,LIPA,CCL24,SNRPD1,JUNB,ALCAM,VCPIP1,SLC39A10,MCCD1,TCEA1,HM13,BCAS4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|
| 2.439e-25 | -56.67 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15095 | 4515 | 16828 | 4835 |
CENPL,NUCKS1,TRIM26,IER3,RAMP3,CYTH4,TMBIM1,IFT172,CPNE2,TOX4,KLRC2,UPRT,SUPT3H,FXN,UBE2G2,MRPL9,FEM1B,MRPS17,SGIP1,MECR,SLC35E4,FAM136A,ZNF518B,CYBRD1,ADCK1,MACROD1,FAM151B,OAZ1,TOPORS,LYZ,WSB1,PRR13,SLC25A5,IRF7,SLU7,MFAP3L,PTP4A2,FAM3C,SULT1B1,RPE,OR8B4,TMEM165,KLHL25,NKAP,LBX1,ELFN2,GALC,RP9,OR5M9,HAUS2,CNPY1,GNGT2,SSPN,LRRC8A,PIH1D1,KCTD3,RDH11,MPG,TANK,BRAP,SYNGR3,CDC23,MBD3,DMPK,SNAP25,RXRG,IGF1,CCR7,GMPS,TTC9C,GORASP2,THUMPD1,GALNT2,ANXA4,RASL12,IL18BP,GRIK1,CMA1,DLGAP4,SNRPE,RRAGB,ZFAND6,TYMS,MED10,TAPT1,SCML1,GJC1,SLC12A2,RUNX1,RPS20,NAA16,GHRL,VPS18,KIF3C,ATP8A1,CIAO1,SUCLG2,PDE7A,DUSP3,AQP11,TLCD1,RBP2,KCTD17,CLEC6A,RASSF8,SSBP4,OR13A1,MAGEC2,PSEN1,FKBP1B,LMO2,EDA2R,LCORL,ANKRD6,FAM161A,YTHDF2,ACER3,MREG,DIRAS2,SRFBP1,EIF5B,ARHGAP12,PFKFB2,UBA52,AP1M1,FUNDC1,ECHDC1,TRAM1,TADA3,IMPA2,ITM2B,MTCH2,SP1,TRAPPC6A,MDC1,MGMT,RPL18,TKTL1,GIN1,KRIT1,VPS72,KCND3,FUBP3,ROCK2,TRAF6,CLDND1,ETNK2,CCDC106,SPRY1,RPS10,RAP2A,MSH6,MDFI,PPP1R11,OR4D5,TEX261,ZDHHC16,OR51E2,GP9,KRTAP8-1,POLE3,RNF10,PSMD3,DTWD2,GPR160,POLR1D,CYP4V2,APLNR,CNPY3,SRI,NCAPG2,PDCL,SUPT5H,STAR,TRIP4,RPL10,SSNA1,GK5,GLCE,SLC25A24,IL2RB,PTGFR,IP6K1,CD209,ST3GAL2,TAS2R7,P2RY4,FBXW4,RPA2,TMEM107,YPEL4,LDB2,GADD45G,RNASE9,TAB2,SRPK2,TRAF3IP3,PIWIL1,CCDC90B,EID2B,PRCP,FBXL4,CD34,THAP1,CPXM1,OR4A47,DCTPP1,TMEM100,RAB6A,CTTNBP2,FKBPL,RGN,CDK7,SIN3A,PSMD7,SCAND1,PLAC1,PYCR2,TNFSF8,CDIPT,ZNF428,PDE2A,TLR8,PMPCA,NOG,ARFGEF1,CRY1,SLC6A2,TNFSF15,AIP,CD40,PIGA,GLOD4,MX1,BOLL,THOC3,S100A11,ATG9A,ZNF622,TGFB2,RBMS2,SLC25A27,VPS54,GRPR,IGFBP3,GADD45A,OR1M1,CD9,RUSC2,BTG3,DPEP3,TMEM183A,PARD6A,TCEA2,LRRC28,PIAS1,PNPLA4,TMEM115,NPC2,EIF1AX,HSPD1,RNASEH2C,DDR1,SLC22A6,TIA1,SPG21,CAP2,SAP18,EXOC3,TMEM81,GPRASP2,PQBP1,PPWD1,FHL3,FAM20B,TICAM2,HSPB6,HSPA5,SERTAD2,GNA11,NRM,MPV17L2,CRYBA1,WDR45,THAP8,NUFIP2,HINFP,GNB3,TMEM229B,BTG2,ITGB8,CCDC3,VAV2,PAIP2B,LRP10,NR1I3,TRIM44,PDE4B,SPEM1,CYP3A43,MEPCE,EIF3G,PMAIP1,TTPAL,UBE2L3,CCIN,CNTROB,FTSJ1,PRND,CPLX2,ABHD10,HUWE1,MRPS11,RAB39B,CSNK1G3,AKR1C1,BLCAP,NINJ1,ICOS,TRIM34,NDUFC2,ITGB5,RGL2,RPS2,TCEAL8,LXN,YIPF3,B4GALT4,CAV1,HFE,GPR35,DDAH1,NDUFA1,HCAR1,TMEM127,GSTA2,FAM53C,MCL1,PNMA3,DPH5,CORO6,OIP5,TRIM29,RB1,PTP4A3,PLSCR1,DCAF12L2,LY6H,TNKS2,LILRA2,STK3,CBLN1,COMMD9,HSPB2,PROK1,JAK2,TRIM36,MRPS18C,NT5DC1,CREBZF,PAQR3,TSR2,CHRM3,FRZB,SPP1,ING2,ARL2BP,ZNHIT6,PRSS23,PLCB1,GPC1,GPR17,CPLX3,TNNI3K,PSMD10,GCLC,NPY1R,ARL4D,LIAS,CITED1,TXNDC17,KCNJ2,EPHA4,CTU1,FBXW7,TNFAIP6,PSMB7,DLK2,CDK12,DMTF1,PLG,ADORA1,SLCO3A1,SPATA2,KCNJ10,SHPRH,TAF1D,PCGF6,GRM1,OR4K2,CXCR3,MAGEB10,HOMER3,HNRNPF,STAMBP,SLC25A1,FAM81A,EHD4,CEND1,ZNF511,BOK,TM4SF18,TNR,OR6X1,ABHD8,ICAM2,STARD3NL,YWHAZ,CAPN2,LSM14A,SLC8A1,OR8H3,TM4SF20,CCNA2,AASDHPPT,REEP4,RNF222,SURF2,SLC29A1,MAGED2,GJA1,TMEM89,GABRA1,CAND1,HSD17B10,PRNP,MIS12,GTPBP8,HS2ST1,CBX3,DR1,BCL9,ASPA,TRPC1,ELMO2,LYPD6,BCL6,SSX2IP,GTF2F1,DLST,TMED9,E4F1,GSTCD,MTDH,USP6NL,SGTA,SNX10,CA2,TPPP3,ZNF263,ANKMY2,ZBTB39,RBM27,CPT1B,CNN3,AKR1B1,SF3B1,TAB1,ADORA3,APEX2,AP1S2,LY96,MAD2L1BP,TMEM47,NDUFS2,PAIP2,TMEM185A,JAKMIP2,PSMC3,CDH11,IVNS1ABP,PIK3CA,FAM83B,SNRNP40,TSPAN15,TMEM38B,NPM3,CRTC2,ATP1A3,PEBP4,GH1,BAX,PSD2,NUDT2,COCH,FEM1C,VTA1,RPIA,PIK3AP1,XAF1,PICALM,LST1,COX6C,PRKRA,TSPAN17,GNRH1,WDSUB1,ZNF451,PRKCE,TMEM170A,RNF133,COX6B2,TAS2R13,DBR1,FSTL1,POLR2L,POLDIP3,RHOBTB3,HGS,UBE2E2,CD81,DPH3,CRISP1,ELK3,LRRC40,MT1E,KLF3,CHRAC1,CCR4,TFB1M,SUMO2,LZTFL1,SNRPB2,IL17F,PPAT,CYGB,NUDT9,GGH,TNF,BANF1,ABHD12,NF2,PARP2,FOXA3,KLHL1,CARTPT,SESTD1,CGGBP1,RPL26L1,PHF13,DUSP21,TRIM45,ATAD1,MRPS34,CYP2C9,IGSF11,SGMS1,MGAT4A,RBBP8,NDST3,FBXO8,OLR1,SLC19A3,CDC7,PRL,MPPED2,NBN,VMAC,TNFAIP8L1,SEC13,IL2,FHOD3,SLC35B3,WDR11,NHEJ1,TYROBP,TBC1D25,PEX13,AIPL1,SNRPG,XRCC5,TIMP4,ACCS,CDC20,WDR5B,ZDHHC4,DYNLL1,RNF139,SMG5,ABCF1,DUS4L,PLP2,OPRL1,HSDL2,LYPLAL1,CSRP1,IRF4,LEMD3,RAB11B,STX5,ARL6,CCND3,FMOD,ADRB3,CMTM7,SPATA4,SLC7A1,CA12,TBC1D16,SLA2,SDR16C5,IFNAR1,MARCKSL1,RAB9A,RXFP2,RPAP3,CCL11,TNPO2,PYCR1,THOC6,HINT1,VCPIP1,PGAP3,LCN15,MB21D2,MCCD1,SLC39A10,HM13,BCAS4,TCEA1,LIPA,PTPN5,SMAD9,TIMM17A,RELL1,RNF182,ALCAM,JUNB,CCL24,SNRPD1,CDC26,SHC3,PREP,CYP4F22,ARFGAP1,PIGC,MVD,STK38L,EDEM2,HCFC1R1,CACNB2,RPL28,SRP72,DDIT3,SLITRK1,HCFC2,PABPC5,PRKCB,IRF2BPL,DCTN3,LSM5,COPE,RBM41,RWDD1,SLC25A3,HBP1,DYNLRB2,CKS1B,SUV39H1,RGL1,RPL4,TTLL10,TP53TG5,DIRAS3,SIGLEC5,HDAC11,ATG16L1,LCP1,AGGF1,HNRNPH3,IZUMO2,ZNF200,TPST1,SKP1,CHCHD2,GCHFR,GJB1,KRT8,PRELP,CSF2,PCYT1B,CFTR,ATG3,INA,OR5AN1,CLP1,CLPX,SART3,PTPRZ1,IFI16,VPS39,FAM174A,MYLIP,ART5,TMEM39A,CDK17,PSMB10,VWF,GPR37,ESD,CDKN2D,ATP6V1D,APOBEC3B,PCBP4,MLH3,CRYBA4,PITPNA,RAB32,FOXC2,CRYZ,BLVRA,SRM,RANBP10,MED27,ADH1B,MPP1,PSMD1,BARX2,HS3ST1,TULP3,OR4M1,BMPR1B,GAD2,RSBN1L,METTL18,TTR,SEC61A1,FAM83A,RHOG,NOL12,SDHC,RGS1,ASB11,BGLAP,COX7B,CDC42SE1,CXCL10,ZNF345,KIAA1958,EID2,MAEA,LYRM2,FBLN5,FOXD3,DUSP18,ZNF770,TPD52L1,ASCC1,CDH7,SMUG1,SVIP,FA2H,ERRFI1,HNMT,ZHX1,SERTAD1,KCNIP2,LPCAT3,GPR83,DPAGT1,CTSA,PPIL3,ZCCHC7,EMILIN1,PRDX3,PDCD5,LRRC14,ZBTB26,BTBD10,GNG11,ARF1,ZMYM6,EIF2B2,TUBA1B,CKB,THAP6,MRPS26,PHF7,HMGB1,RPL7A,CXXC1,FIG4,LSM12,DOK5,MAP2K3,SEC22A,DCTN4,ARF6,B3GALT2,PPT1,ZDHHC24,RCHY1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R2E1,FLOT1,ORC6,SCNM1,MCM4,FAM177A1,DCTD,SLCO2B1,CX3CR1,IGF1R,CHMP4C,CEP19,SOX14,PDAP1,KLHL22,UBP1,MAVS,ASB7,PRKACB,APOBEC3H,LANCL2,GLRX2,ODAM,KLF1,VDAC1,FEN1,CLPB,ADD1,CBR3,CLEC2B,SEPHS2,VGLL4,DNAJC19,SCML2,CCNY,CHKB,GPR176,PKP4,CLDN12,ELF5,OTOS,CNOT2,CRHBP,ERAS,GSTM5,ZNF326,PLEKHO1,MYBL2,DENND2D,COPS7B,KLF4,OR4D2,OR10A6,ACBD6,RNF34,PREB,NFKBIA,NPW,TUSC1,ATG7,TAF10,FAM53B,PRDX1,TRIM68,ETF1,LRRC8B,POLR2B,TSNAX,GTDC1,LRRC61,UBIAD1,DHRS13,PARL,FBXO22,REG1B,GPM6B,SLC7A8,RFC3,ATP6V1A,SERPINC1,ACP5,HLF,EGFL7,TMEM59L,SMPD2,ASTN1,NCBP2,SOD1,ATXN10,TBC1D13,DTWD1,REN,CCR1,VEGFA,FAF1,DECR2,AVL9,IQCK,TP53INP1,NAPA,NOTCH2,SOBP,PTPN11,TM4SF19,CRAT,GNPDA2,TMOD2,USP16,PFDN2,LTB,TCEAL1,HARBI1,TMED5,HMGCS1,SLC25A12,AK3,CLCN6,RPL32,PSMA1,DDRGK1,SHOC2,HDHD3,MTF1,MSTN,RPL27,PPP1R1A,PRICKLE2,RNF148,CLDN9,DIO1,VGLL2,SLC16A10,TRMT112,SLC35F2,SYNCRIP,UBL5,BTN2A2,CSH1,IFNB1,CCNH,SEMG2,KIAA0513,MNS1,POLB,POLA2,UBASH3B,TOR1B,SPSB3,ABCG2,MRPS9,LTA,FAM83C,IL1R2,TMEM41A,ACVR1C,FAM181B,NKIRAS2,STUB1,PIP4K2C,KLF9,ST7,AVPR1B,UBLCP1,GSTA1,SRSF2,SERPINB1,TRAK2,TEX264,SNRK,DDX50,HINT3,VRTN,SLC25A10,RPRD1A,GTF2H5,STK4,BST2,PPP2R2C,CYP1A1,ST8SIA5,PLS3,SLC22A17,TNKS,TYW5,RPL27A,CBLN2,NUDT12,HTRA2,JAGN1,SNAP29,NDUFAB1,GPR171,DHX38,PTK7,TMEM147,USP8,LGALS8,COX8A,METTL15,NEUROD2,PGRMC1,FBXW11,CINP,CNDP2,PPFIA2,OR4D6,THBD,IL1A,BCL7C,CREG2,PCYOX1L,AGPAT5,PLD3,LRRC3,HR,DNTTIP1,FBXO44,ARPC3,DKC1,CHST2,HNRNPA0,RHOBTB1,FZD3,CD247,IKZF5,NXT2,TMEM126B,NDUFS6,CTSC,SPRED2,CDAN1,OPRM1,PDE1B,PIK3R2,PCNA,DDX23,APOBEC3G,GNG12,PABPC1,NTRK2,LPAR2,FKRP,ELMOD2,OR10A4,USP15,CNRIP1,GNAZ,RTN4,GLRX5,ISX,GAMT,SIAE,RNF144B,DNAJB9,ARG2,MUL1,SMG9,GNG10,MAPRE1,NRN1,CTXN1,SEC22C,ZFAND2A,METAP2,MME,CENPW,SDHB,GFPT1,ATG4C,SNRNP48,FRRS1,TXNDC12,RWDD3,EPHX1,CKS2,RORB,CXCL13,ABHD5,FDFT1,SIT1,NEGR1,MOXD1,RPA3,ADAM21,CLDN3,PTAR1,MGAT5B,UAP1,THAP7,INO80E,DEPDC1B,RLIM,PTEN,UCN,CRLF3,CHPF2,NDUFAF3,IER2,CCS,RASD1,SHISAL2B,SCGB1D1,NLRP3,ILDR1,BMPR2,COMMD3,RND2,PPP1R1B,OLFM3,SCG3,TOM1L1,KDELR1,KRAS,RPS16,RBM22,RRM1,ORC5,ILF2,OXSR1,BAG3,ZNF365,PSMB1,ZMYM3,CRIP1,ASNSD1,CNTN2,DKK1,HERC4,NR2F6,CHCHD4,CHIC2,MRGPRX3,MTA2,CCDC86,SUFU,FBXL19,LAPTM4A,KCNC1,OXTR,PGGT1B,SLC38A7,FGFBP1,MFSD5,MRPL18,METTL21A,CHAC2,G3BP1,POP5,PSORS1C2,RPS27A,PCDHB13,TPD52,DBT,ELOVL7,RAPGEF5,DAPK3,DSTN,TMEM101,NUF2,HINT2,OR13C8,SLC16A1,RPS7,PSMD4,NPPC,RELL2,TRIM15,GPX1,RAB27A,GRAP2,RHEB,FBXL14,OVOL1,DHX15,OCRL,ZNF664,MLC1,MAT2B,PDHB,DDX46,TSPAN18,GANAB,RPS6KA4,BBS5,XCL1,SLC6A6,CCDC134,TCF19,SLC30A7,STX11,OR2Y1,PMP22,SERPINA1,LARP4B,HSPA13,LSM10,ANKRD34B,PPP2R5E,SLC11A2,SH2D1A,LMAN1,NPSR1,MRPL11,SCLT1,LRRTM3,DAAM1,STAT2,SAV1,TAGLN3,EPCAM,PCDH17,SRSF7,PRR3,IL22,TOR3A,GLRX,UBA3,CBLL1,TMEM179B,TOMM22,BFAR,CSGALNACT2,CSTF3,HENMT1,RPL7L1,ST6GAL1,KCNJ3,COMMD6,B3GALT1,TMEM30A,AFAP1L2,GNPDA1,IMP3,IRAK4,UBL3,CYP21A2,GNAO1,NCDN,TMEM117,MRPL34,NDUFB6,SNX22,SFXN2,FASTKD5,CST11,USP13,SDCBP,NDP,SNX33,TMEM42,SRPRB,CEP85,ERLEC1,DRG1,FGF3,SNX12,POLR2D,SMNDC1,PDP2,NEURL2,KRT222,CNTFR,ARPC2,KCTD11,OPTN,GPR146,APPBP2,CLEC7A,ENHO,MYL12B,GINS3,SH3BGRL,EXOSC3,SRSF4,NECAP2,PID1,ZHX3,ATP6V1E2,IL7,RPS3,OR1F1,HAX1,EGR2,LRRC20,HBEGF,AIF1,CALU,TMEM60,CHN2,RAD23B,UFM1,USP30,ORMDL3,FOXJ3,MAP4,HHIP,LUC7L3,NMBR,LGALS3,FAM91A1,LCN12,CTNND1,RAB3A,DDIT4,SMYD3,CA8,YIF1A,OR10Q1,UTP6,HMGA1,OR1S1,SH2D5,IPCEF1,TSPAN11,MND1,GGPS1,TFRC,TTC8,IDE,ZNF267,AUH,C1QTNF1,ZNF652,ZNF177,HSD17B11,RPL12,UQCRQ,KCTD12,DNAJC7,CD83,FAM187B,GABRB3,MRPL49,YWHAH,PLCL1,MTMR2,ICAM1,DUSP22,SOD3,ADAMTS20,GFOD2,LSM2,PABPC1L,TMBIM6,CCT8,ACTR3B,TFDP2,ZNF22,C1D,RBM15B,EEF1B2,ZNF189,MIF,APTX,AP2A1,HRH2,BCL2A1,TMEM45B,SPINT2,ZNF688,RBBP9,SPSB1,FBXO11,DGCR6L,WNT10B,LRRC8D,ETFB,VIP,NTNG2,TMED4,HEXIM2,TBC1D17,HSD17B1,SLC25A46,CYB561,BET1,FCER1G,PTRHD1,TOX,RWDD4,KPNA6,IRF8,GSTM3,SYNDIG1,FTSJ3,TSEN34,HBA1,MZT2B,LIMS2,NECAP1,GPC4,OSGIN2,MGST2,SENP8,STX7,GADD45B,PPM1B,TRIM35,TRAFD1,PKIA,CRELD1,NFKBIL1,INMT,TP53,KIN,PRDX6,AP2M1,TAX1BP1,ARF4,GABPB1,CALY,TAX1BP3,ZNF790,RDH12,DNASE1L1,PSMA4,GABARAPL2,PML,MT3,EIF1B,OR10A7,SERTAD3,PPIF,SETD7,MTHFS,DUSP6,ZBED3,DAG1,RPS12,CYB5D2,MAF1,TXN,TSPO,LYPLA2,RPRD1B,DCAF4L2,RNF181,STYK1,POP7,LBR,FBXL7,CYP11B2,GPD2,OMG,CELA3B,THNSL1,SLC1A2,COX5A,CAMP,TRMT61A,RHBDL3,PHF21A,GNPTG,OLFM2,ENO1,RPL24,ORAI2,CHST7,SERPIND1,CRYL1,ZNHIT1,MECP2,NUP35,SLC25A14,PRDX4,ELOVL6,ALOX5AP,TFPT,CSTA,RGS6,RASL11A,CLSTN3,TBC1D19,SERPINB6,SYBU,EXOC5,NAA15,F11R,ADK,G6PD,WDR55,RALA,FTHL17,VASH1,GAPT,TLR7,PPP2R5A,RNF128,ACADS,PTGES,SAR1B,TLR1,CAPG,OGDHL,IL12A,RHAG,FBXO34,HCST,DHRS1,PAPOLA,OR5B3,BRMS1L,CHORDC1,ANAPC16,ZBTB16,ATP1B3,GNB1L,GNL1,KIAA1143,SELL,ZNF473,ROMO1,CRYAB,PPY,APOC4,TAF7,SYNGR2,RNF11,CYTH2,CD28,ZBTB25,FXYD6,NAB2,OR4S2,WDR82,TLR10,SEMA5A,APBB3,MCMBP,KCNAB1,PPP1R3C,CRADD,AGTRAP,TNFAIP1,TMEM11,CHPF,REEP6,MATR3,CNOT6,LAMP3,DDX1,DAP,KDELR2,RNF40,RPS26,DPM2,RNASE6,TP53I3,CFL1,KLHL3,IRGQ,BRIX1,PSENEN,SLC2A8,ENO2,OXCT1,MANBAL,PNMA5,CD86,EXD2,KBTBD6,FARSA,UBE2H,ZNF704,PRR5L,CD14,SLC25A39,G6PC3,RANBP6,FGF23,GOSR2,SLCO1B3,CYP2R1,HTR1A,TMX2,WSCD1,ELF1,SFRP1,ZC3H11A,CCL27,PPP1R8,MAB21L1,KCTD10,RAB35,SHISA2,CCL28,MKLN1,EEF1E1,CMTM6,VPS26A,CD40LG,FEM1A,LILRB4,MYC,SMG8,TMEM50A,SP2,HEBP2,CALML5,PNMA1,VAPB,TCF21,SLC6A3,CASC3,TUSC2,TIRAP,RPS9,MYL6,GEMIN8,SEC23A,TOP2B,OR5V1,GPR173,PSMG3,NLGN1,MORF4L1,TMEM174,CACNB3,AGR2,PCBD1,TTC23,CD63,AGA,CPSF4,LCN8,PARM1,CLEC1A,AKAP1,DNAJC24,KBTBD3,PSMA6,PCSK9,IL2RG,PIWIL3,PSEN2,SLC35F1,CCM2,ALB,FTH1,SNX1,CLN8,VPS16,ACO2,SYK,SLC25A26,SLC38A1,DUSP10,BACE1,TNFAIP8L3,CDC42,SLC48A1,DVL2,TESK1,FAR2,BRD3,SURF6,TMEM108,RPL39,C2CD4C,OR2AT4,TTC33,GAS2,EEF1A1,TRAPPC4,UCHL3,BET1L,KLHL26,MMD,WRAP53,PRKCA,PAAF1,TFPI,COX11,NPTX1,CLIC4,HMOX2,HNRNPH2,ADM2,IZUMO4,AHCYL1,ALDH1A3,ENC1,SAMM50,KCNJ8,PDE8A,PSMB9,HOMER1,FOXP1,SLC4A10,PYGB,ALPL,SLC20A1,EXTL2,RCCD1,C2CD2,EFHD1,LAP3,ADIPOR2,DGCR8,RNF5,TST,RPL9,API5,KCNS1,SPRYD4,CRYM,SAMHD1,TPH2,MRPS18B,ST3GAL4,EHD3,DOLK,NT5C2,ZMAT2,SRXN1,FKBP1A,P2RY12,DNAJC30,CCDC92,ERVFRD-1,MAN1A2,POLD4,AKT3,RBP5,EIF3D,DNAJC4,PAK6,ELOVL4,CHMP2B,SKA1,CSNK1E,GRB10,ATF1,FAS,ABCB9,RBBP4,TMPO,UBTD1,MAD2L2,POLR3GL,COX6A2,ARMCX3,OR5A2,CUL3,COX16,SDC2,RPL10A,CTDSP2,ACVR1B,FAH,COQ10B,POLR2G,SNX14,LAT2,FITM1,ACTR1A,C2CD2L,DNAJB4,TXNRD2,RAP1B,RAD21,KLHL9,TIMM8A,NPC1L1,CARHSP1,PI16,MAP1S,BHLHE40,RPL29,GLRA2,HDAC3,MRPL53,GDPD3,ARPP19,ANAPC4,MPHOSPH6,COX4I1,FABP4,LRRC4B,GREM1,TOMM40,LBH,JAK1,TBC1D10C,NKX3-2,MAGOH,CCL19,MLF1,GTF2E2,PSME2,AZIN1,FGF1,ABCB1,INO80C,AZGP1,HBE1,KTI12,CDCA3,RAB3B,SMAP2,DEFB116,TNFAIP8L2,DHRS3,NDST1,SYN3,ZCCHC10,GPBP1L1,MX2,AAMP,LYG2,MFSD6L,ATP6V1G1,MEST,FZD4,WDR77,MTPN,SERPINB10,TSEN54,ZNF24,FBXO42,TMEM215,BTF3,MMP9,CDC73,UBAP1,ZYX,LHX2,DYNC1I2,S100A6,CYP27A1,TMIGD1,DNAJC5,PGK1,VRK1,ROPN1B,MYH2,SLC7A9,ALKBH4,HEBP1,PACSIN3,GSTO2,KBTBD2,CTNNBIP1,GNG7,ATF4,PIWIL4,CSNK2A1,KPNA1,RARRES2,LSM3,AFTPH,OR4D9,RS1,KIT,P4HA2,JOSD1,SUPT7L,FBXO32,ANAPC2,AGK,SBK2,SORD,CCT5,ENPP4,PSMB5,MCOLN1,FKBP14,IDH2,RAB18,IMPACT,AGER,CD58,PRPF4,ARMCX5,ZNF593,GHITM,TUBG1,RPL15,CCDC47,SCFD1,TTC4,BUD31,SRP54,TMX4,CAMK2G,PRMT2,TACR3,CIB3,CD200R1,CRYGB,PPP3CA,KCNJ11,FAM89B,PEX3,RCVRN,CCDC127,OR4K1,PYGM,SHC1,HCRT,CAMK2N1,FGFR1,RBM17,PCDHB8,HEY2,RFX4,FRMD8,PKNOX1,ADRB1,ZDHHC14,LRP12,NPY2R,SLC35E3,SPTAN1,RNASET2,TRAPPC1,FAM199X,CLDN11,NIPA2,PAEP,RABL2B,SLC25A21,RBBP7,PGS1,RMND5B,PTPN1,SETD5,HNRNPC,NFIL3,HECW1,TRIM37,GALNT12,ARFIP1,PPARG,SPR,ARMCX2,SIX5,TRIM21,ACTA2,CDO1,CCNI,PPIL4,RAB11A,IL20RB,DKK3,SF3B4,DPP10,PRRC2A,CRABP2,FGD2,APEH,AKT1,DLX1,COMTD1,FNDC8,TLR9,FIBIN,L1CAM,MRPL13,MDM2,MGP,EHBP1,AK2,SOCS5,GALNT1,CCDC69,PSMA3,TMEM156,GSTO1,NUDT3,B9D1,RND3,CNP,TOM1L2,GNRHR2,UST,PFDN5,EXOC8,LYAR,TRIM32,PDIA6,SDR42E1,UBR7,SNRNP27,PRIM2,CD99L2,DOK4,ARHGAP1,KLK9,PLA2G5,KLHDC8B,RNF141,GFM2,MRPL23,GDI2,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,E2F6,TMUB1,TRIM3,C1QC,POLR3H,ZNF207,TMEM219,ATP6V0B,EDF1,LYPLA1,LIG3,RPS14,UGCG,MEAF6,SLC17A5,SLC25A31,ZNF671,LMO4,CLU,KIAA0232,ATPAF2,NCKAP1,NRP1,CDK5R1,GLUL,CNIH4,XAGE5,ZNF319,SEC14L1,ID4,ZNF397,APOBEC3A,CCR6,ZMYND19,SLAMF9,TAAR1,NAIF1,TRIM23,NHP2,ING1,STRBP,P2RY1,IRF1,OR8B8,ATP6V0E1,UBE2D3,CCT2,ARMCX1,UBE2A,PRPSAP1,TCP11L2,GRPEL1,ELMO1,FGFR1OP2,GABARAP,OR4D11,GAL3ST1,CASK,LTBR,SNAPIN,KLK3,SLC30A5,MRPL24,MRPL50,ZNF304,IMMP2L,SLC35A1,DHRS4,ENY2,RAG1,FAM78A,PPP1R2,MIOS,RMND1,SLC38A9,OSM,IL15RA,JAKMIP1,GPAA1,TLR3,IDH3B,CTNNBL1,GRM2,CYP11B1,SENP5,GNRH2,CHDH,FAM8A1,NCR3,ITK,EIF4H,MYL12A,HSD11B1,CYP39A1,SWAP70,POLL,NONO,ALDH1L1,MAK16,TSSC4,H19,SPRED1,SNAPC1,SNTA1,GPR37L1,NDUFAF2,SIVA1,GFOD1,OR2A2,EIF4EBP2,TCP11L1,SOST,SV2B,HPCA,MTMR12,DUOXA2,TRAF7,MMACHC,TNFAIP3,RAP2B,ABHD16B,RRAGA,ETV6,TAPBPL,FYTTD1,NOL4,IQSEC1,SIRT7,ADCY3,SNRPD2,CDK6,CWF19L1,ESR2,DCAF5,CYP2D6,INTS12,SOCS2,RAB8B,CTNNB1,CLEC12B,SFTPD,ENPEP,NAB1,FGF13,PRKX,PROX1,SYNGR1,LSM6,RTP4,USP38,ZNF174,SLPI,CERK,USP39,COX7A1,FBXO9,CCND1,OR2W1,RPGRIP1L,TMED3,ACOT13,WFDC13,SETD4,LCN6,RHCG,ARHGAP21,SCG2,FAF2,BMPR1A,KLF10,AP3S2,MPHOSPH10,S100PBP,TMEM33,MRPL47,STX8,BATF,TOLLIP,TGFB1I1,DUSP1,NFYA,FAM200A,S100A10,CACYBP,CTSK,URM1,CETN3,PWP2,MTAP,RAB3C,NDNF,CHST9,CPT2,ANP32B,CD164,PPIB,CDKN3,BPGM,PRKD3,CYP4F8,SLC5A6,DEK,NLGN2,SCAMP2,NUP107,OR52M1,SPEF1,FABP5,MRGPRX4,PGAP2,CTSD,RBCK1,MRPS25,SPATS2L,NOP58,AKR1A1,NFE2L1,MIA2,BACH1,KIF2A,INPPL1,CRYBA2,DEGS1,ID1,PTDSS1,ENTPD4,SLC35A2,ARMC8,FCAR,NPTN,CCDC42,CYC1,POU1F1,TF,CREB3,RNF103,XPO5,SURF4,INTS10,EXOC2,XPO1,THRAP3,EEF2,SLC25A32,EFHC1,GJA10,SLC7A4,ZNF513,ZMYND11,APOBEC3C,GPR162,RNF187,PRCC,GSK3A,PCDHA5,SLC20A2,NUBP2,PFDN6,LDHA,UBXN10,RC3H2,DNAL4,ATP2C1,FATE1,THOC1,ABCC5,RANGRF,CCL25,GNMT,AQP4,TXNIP,CREBL2,DHX9,SLC39A9,FURIN,IL23A,PSMD6,EIF4EBP3,WDR37,ZSCAN1,OR51S1,ENDOD1,CIRBP,CXXC5,OSR2,GALE,EIF2B5,SH3GLB2,WBP2,GTF2A1,FUT8,SPOCK1,PHKG1,LASP1,UTS2R,NEK7,RPL37A,SERPINH1,SIPA1L1,STAMBPL1,PGBD2,HSPE1,ZKSCAN1,CLDN14,HSPB1,KCNA2,B4GALT6,LHFPL1,OR6M1,NUDT16,DHX16,TRA2B,SOX21,HADHA,LEAP2,STX17,LEPR,WNT7A,CXCL1,XPOT,PDIA3,FRA10AC1,EIF1AD,NDUFB8,APH1A,ISYNA1,KRR1,NLE1,SNAI3,CDC37L1,PELI3,RPRML,MSX2,CCL21,NDUFA5,KCND2,NEDD8,CXCR1,HBB,FGF17,TRMT6,PTCRA,FBXO30,TIGD7,POLR2I,CD2,UCKL1,RAP1A,ACAA2,RABAC1,WWP2,IL34,DFFA,ST13,LPXN,RASGRP2,TAC1,OPA3,LMBR1L,NPVF,AKR1C2,IGFBP4,IPP,NQO1,SPATA2L,TBCE,CD3G,BRMS1,PAOX,CDKL2,GAS8,CHRNA7,KIF1C,HEXA,ADAT1,OCEL1,BRI3,RBM23,TMED1,OXNAD1,OR10G7,ISG15,SNX24,ACADSB,STAT6,PHYHIP,FN3KRP,WIF1,DYRK1B,AMT,RAB9B,EZH2,ARCN1,KCNIP3,INPP4A,PDYN,ZFP1,B4GALT3,CD226,VPS33A,SACM1L,CRBN,TRAPPC6B,VAMP2,CCNF,CTNNA1,RAB2A,WDR44,GPIHBP1,BEND5,CMPK1,SNRPA,RAB5C,PNP,PCDH19,AP1AR,TIMM10,STK38,CSTF2T,IFI35,PSRC1,FBXO25,C1QL1,CAV2,FOLR1,RAB37,SLC6A11,LYNX1,RPL23A,TMEM59,IL6ST,TIMP1,TXNL1,DERL2,MLF2,PLEKHJ1,PPP2R1A,PTHLH,MRTO4,SLC25A4,SMAD3,EIF4B,HMBS,CD2BP2,TDRD7,CCDC65,LDHAL6B,AMY2B,NDE1,RBMX2,INHA,OR5L1,RPAP2,RGS5,RAB1B,HRH3,ZBTB45,ABHD13,UBE2D1,LY6G5C,SLC4A8,SNIP1,FAM168A,ACTL6B,GYS1,SLC23A2,ROGDI,PGM2L1,PIWIL2,SOS2,AKIP1,SDHAF2,CLIC2,MED11,OTUD7B,PPFIA3,RBFOX2,FOXN2,GK2,CDKN1A,SLITRK2,ORAI3,ELSPBP1,STX18,CPSF2,CDH8,TMEM14A,TCEAL7,GDE1,PCGF3,GPX5,MOV10,GLT8D1,NGB,UQCR11,MYEF2,PNPLA8,TAF5L,HIGD2A,TEX12,TOP3B,ZCCHC9,SLC43A2,TMEM91,DDX4,KLK5,LIX1,CAB39,GRIA2,LRRC24,MRGPRX2,PPP1R16A,MT2A,ATP1A2,PXMP2,GMPPA,CYB561D2,SLC7A14,DDX42,BNIP3L,TUSC3,SPRR1B,RPL6,CLDN8,ADAMTS1,CXCL14,FMO2,TMEM177,RPP25,RAN,RBM12,SQSTM1,GLIPR1,RNF122,KIAA0408,BICD2,SERPINA5,CREB1,KIAA1191,CCL17,PAFAH1B2,GTF2F2,KCNH1,POLR3B,HAND2,PGR,BRD9,HSPA14,CXCR4,NPY5R,KRT7,PLEKHA8,WDR3,GJB2,MANSC1,SRP14,NUS1,TMEM106C,SLCO1A2,KCNK10,TMCC2,ZNF609,APLN,ACP6,SYNJ2BP,TMEM164,ACTR2,OR4F6,CRYBB3,PTRH2,FOXS1,TAS2R5,KLHL15,TRAM1L1,SESN2,PAPOLB,PLAGL1,RFXANK,CHST1,MPV17,EHD1,PPP1CB,TRAM2,GCA,ISCA2,RABL3,UPF3B,ZNF576,FAM107A,RNF167,RAB33A,CRYGD,DNAJC8,PPDPF,TNFSF18,CHI3L1,RNASEL,EIF3J,FERMT2,TOMM40L,GIMAP2,GNPNAT1,UTP23,SPTBN1,HIRA,S100A8,CD47,TMEM50B,JUN,IFNG,WWP1,RHOJ,CBLN4,PTGER1,SFT2D2,CMAS,RAB23,CCR3,OGG1,ZNF687,OPHN1,SUMO3,YPEL5,PPID,CCL8,RFTN2,TPPP,RB1CC1,CAPZA2,SLC35E1,STX6,FANCG,OR2A25,PLA2G15,GGCT,RCBTB1,ATP6V1C1,HNRNPA2B1,ACAP2,SCD5,LHFPL2,HNRNPK,PAFAH1B3,PRKAG1,NFKB1,POMP,RPL26,OS9,RIOK2,MRPS28,OAT,CLDN22,EGLN3,FOS,DYRK2,IPO8,TMSB10,ARMC7,ATAT1,CIDEB,TMEM123,AIF1L,ZC3H7A,ZBTB5,DSTYK,CDKN2AIP,RGS7BP,SFRP4,RER1,FCN2,FUNDC2,MRPS23,ZNF862,ATG4A,SYP,CSRNP1,POLE4,HSP90AB1,ISG20L2,GPHN,TOM1,BCL7B,SEC61B,GPR65,PAPSS2,TCF23,CHGA,EIF2B3,HTR5A,TMX3,NRSN2,TOP1,TMEM144,SNX17,BCS1L,APOO,GPR137,CYP2C18,NDUFS8,MYO6,OPRK1,GCNT3,PGPEP1,F9,NKX3-1,ACAT1,TMEM184B,KDM4B,ZNF287,RAB3D,CLDN4,SLC13A5,LAMB2,OAS1,NKIRAS1,GIT2,SDF2L1,RUVBL1,GTF2B,CXCL3,PRPF19,CREBBP,PDCD4,LDOC1,GPAM,RDH10,OR4Q3,HTR1F,POPDC2,GPX6,TGIF2,GREM2,RPLP2,FAM98A,ACBD7,CDC42SE2,TRIM54,CRTAP,UHMK1,ANKRA2,ADIPOQ,ALKBH5,ERH,AKAP14,CRYBB2,NDUFAF4,CCNB1,CTDSP1,METTL2A,CLDN1,ABHD6,TFCP2,SAT1,R3HCC1,CSGALNACT1,SMU1,SLC35D1,COL1A2,RMI2,PTS,TOR2A,AMIGO1,JPH4,MBL2,MAP3K11,GNG2,EDEM1,VAMP5,METTL14,MRPS21,PYROXD2,LRP6,RAC2,STK24,LCA5,ST3GAL5,ZNF501,CEP97,PARP11,SLC32A1,ST3GAL1,SOX2,CSNK1A1L,DERL1,IL18,UQCRH,DPEP1,PRKAB1,STXBP1,KLC2,PAX9,MTHFD2L,IRF3,CD36,STOML3,TSN,STAU1,SERINC3,SLC41A3,TMED7,DNAJC3,RNASEH1,FKTN,KLK6,NME1,DUSP19,RGS2,STMN2,MBD5,KCNMA1,BCL10,NOS1AP,ADPRH,PDHA1,KCNK13,RBM7,TRAF2,BRCA1,PCDHB1,ABHD4,CNNM4,NR1I2,DPY30,NPR2,CDK4,TMEM204,GPX3,PROS1,B9D2,EWSR1,ZNF592,MTRF1,ELP3,YAF2,CIB2,MRFAP1L1,ACSL4,TGFB3,ABHD14B,MRPS16,EED,BECN1,LMNB1,TES,CCDC25,CALHM2,ADO,GMPPB,HSPA8,SLC19A2,CBR4,VMP1,OSTM1,CHMP2A,EMP3,TFE3,MT1M,DEFB114,IFNA10,ITGA6,CSNK1A1,COMMD8,TSPO2,OLFML3,GOLGA7B,EFNB1,THTPA,PREPL,SH3GLB1,UBE2V2,IL10,RPLP0,NTN4,RTKN,PHYH,FUT9,CD274,EIF3K,B3GALNT1,CREB3L4,ZBTB17,BCAP29,FABP7,RINT1,OR10G9,TSPAN5,BZW2,SPECC1L,KHDC1,NAT2,LHFPL4,CDKN2C,COX4I2,TMSB4X,TRIM5,EIF4E,SSU72,IGBP1,AKAP12,RAB40AL,DDX39A,SNAPC3,SNCG,BLOC1S2 |
| 3.057e-25 | -56.45 | OGT (O-linked N-acetylglucosamine (GlcNAc) transferase) | protein interactions | 8473 | 927 | 404 | 19454 | 5460 |
FEN1,SAP30,EZH2,PLD3,RBPJ,RPS24,ZBTB14,RBBP7,G3BP1,HS2ST1,PCGF6,STOML2,UBXN6,CLPX,PRPF19,TAF7,EIF3D,CSTA,PPP3CA,AHSA1,CIART,FBXO32,MYEF2,HP1BP3,COPS2,TSG101,RPL7,MPP1,ATXN10,NOP58,ETF1,EHD1,PPP1CB,RTF2,THAP6,UPF3B,NUP50,CCDC86,G3BP2,COIL,PSMC1,CUL3,SP1,RAN,DYNLL1,RBBP4,UMPS,BTG3,YTHDF2,CCDC47,THAP1,UBR7,EEF1A1,HSPA13,DMAP1,SRP72,RAD23B,PPME1,ILF2,ZNF787,TEDC2,TMX3,RING1,SEPTIN7,HAPSTR1,TOM1,THRAP3,CAMK2G,MDC1,EIF3E,OLA1,CTNND1,ISYNA1,CALR,GTF2E1,SNAP91,DNAJC7,HACD3,FAM199X,DBT,CCND1,SAP30BP,PSMC4,RBFOX2,ATG16L1,HSP90B1,LMNA,P3H1,RPLP0,OXSR1,MTDH,SQSTM1,RPL4,CTSD,CREB3,USP14,TUFM,NONO,AR,KPNA6,ATP5F1A,PIP4K2C,TADA3,STK24,GSK3A,YES1,ARMC6,ZNF622,DDAH2,RPL22,TENT2,CAAP1,CRKL,RHOBTB1,AAMP,ZRANB2,PABPC1,CCT8,PDIA6,RTCB,TRIM11,RUVBL2,HNRNPDL,POLDIP3,CIAO3,RIOX2,GSTM3,STK4,FKBP4,YWHAB,TCP1,LYAR,PAIP1,FAM98A,NUP62,PAK2,PALS2,PIH1D1,SNRPA,HIRA,STK26,HSPA8,P4HA2,HDAC5,STAU1,OXCT1,GON7,PRCP,SVOP,TBCE,HMGCS1,FTSJ3,PHF21A,SF3B4,ATP5F1B,PSMD4,TOM1L1,PPP5C,UBL4A,SRFBP1,IK,NHERF1,PSMC3,SNIP1,NAE1,RPL3,ERO1A,KPNA2,FKBP8,HCFC1R1,RBM17,KARS1,CSNK2A1,SNRNP70,TUBG1,RPL10A,RPS2,SYNCRIP,NKAP,IFRD2,CDC5L,TMPO,RBM42,VIPAS39,RPA2,VPS4B,QRSL1,RPRD1B,TCP11L1,GSTP1,POLD2,HCFC2,THUMPD1,APMAP,HNRNPH2,RBM22,KDM1A,HSPA5,ZC3H15,MAT2A,RC3H2,SPOP,EIF3G,SNX5,ZBTB38,UBN1,ACOX1,RPS3,PSMC5,EIF2S2,GABPA,PPAT,BCCIP,SMURF1,DLG3,NFE2L1,ZNF397,FAF2,PPP2R1A,GDI2,BZW2,HNRNPA2B1,ZYX,HSPD1,SRSF7,PSMD12,PDIA3,ZNF207,HNRNPA1,TMEM30A,VPS4A,HNRNPD,RPL8,RPL9,KRT8,NUF2,STK3,EGLN3,TOR1AIP2,ACTL6A,LARP4B,ANXA7,MFAP1,THAP2,FKBP10,DNAJC3,PAFAH1B2,NOP53,PMPCA,PKP4,CDC123,SMARCE1,PRPF31,BRCA1,YWHAZ,ARHGAP19,SETD7,ILK,LSM14B,HSP90AA1,TRMT6,TUBB,ACTB,TAB1,B4GAT1,CCT5,PGM1,CD2BP2,ACTR2,VRK1,FARSA,NOC4L,TTC4,HUWE1,RIGI,SPATS2L,GRSF1,ATP1B1,KRR1,RPL12,TRAK2,TOMM70,CDK9,ARHGAP1,COQ8B,UQCRC1,PICALM,SHOC2,WTAP,RARS1,SH3GLB2,PRIM2,RPA3,RTN4,CXXC1,HSPA14,ASCC1,SMAD2,EIF2AK2,ENO1,TUBA1B,METAP2,CCNF,GXYLT1,TRIM27,DEK,RPS7,TUBA1A,PLS3,TUBB4B,MOB3C,LSM14A,EWSR1,RUVBL1,HNRNPF,CBLL1,TFG,RPS4X,WWP2,RPL6,YWHAH,YWHAG,XPO1,CRTAP,FUBP3,ZNF436,SIN3A,WDR82,HNRNPL,HSP90AB1,CCT7,LAP3,TBCEL,SEC62,CNDP2,NUFIP2,DDX39B,PCGF2,DDX5,EEF1G,UFL1,PACSIN3,HNRNPAB,HNRNPC,LDHB,MYC,CREBBP,KANSL3,FBXW11,CKB,CCT2,SERPINH1,COP1,DLST,SURF2,ESR2,RPL10,RPSA,TP53,ESS2,BIRC5,DHX9,CLPB,HNRNPK,PLEKHO1,EDC3,API5,GAPDH,SMCHD1,RPL24,TRMT5,KPNA1,NT5DC1,MIF,LMAN1,MBD5,CHST7,LUC7L3,IRF3,BAP1,RBM23,PGK1,WDR55,CCNB1,PSMB2,GORASP2,ST13,TLR9,ATP1B3,UBE2H,ALKBH5,PDCD4,IGF2BP1,OAT,PSPC1,PPP2R5E,CSNK2B,PHAX,SRP54,TRAF7,DAPK3,UBA3,DYRK1A,IDE |
| 3.738e-25 | -56.25 | negative regulation of macromolecule metabolic process | biological process | GO:0010605 | 3170 | 1179 | 18204 | 5365 |
MIR24-2,CUL3,NR0B1,NR2E1,MIR944,RAN,MIR30E,MAGED4B,FOXP2,YWHAZ,MIR301B,MIR922,NIBAN2,MIR218-1,H2AJ,SOX14,ELK4,MIR493,CRYM,BEX3,MIR137,MIR769,NSMCE3,PPM1B,MIR532,MIR455,MIR298,NUDT16,EIF3E,MIR194-2,MIR652,VEGFA,MTA2,IL23A,CTSA,SATB1,MIR874,CCAR1,TIMP1,CEP85,NF2,KLF3,CCDC85B,H1-3,MIR891B,SERPINI1,MIR572,ELK3,EID1,FASLG,MIR140,HNRNPA2B1,MIR939,THY1,PIK3CA,SPOPL,APEX1,CBX7,SUPT4H1,STAU1,MIR139,PDCD4,ROCK1,SERPINB11,ETV6,MIR143,MIR15A,PHAX,MAGOHB,MRPL13,C1D,APOBEC3A,H2AC1,G6PD,MIR183,RPS13,MIR373,PIAS1,VIP,MIR32,ZBTB39,MIR632,TBK1,XRCC5,H2AC25,MRTO4,DUSP6,MIR7-1,PSMC5,NPPC,IGF2BP1,PDE2A,CIART,RBM42,POU1F1,DNAJC1,MIR16-1,PIH1D1,DCUN1D3,NR1I3,TMBIM6,BOLL,HNRNPL,ACVR1B,PRR5L,MIR208B,NOG,SGF29,HDAC6,MAGEB1,MIR616,FBXW7,MALSU1,MIR592,MIR129-2,CCAR2,APOBEC3C,ALKBH4,MIR363,VSIR,NIF3L1,ATRAID,MIR101-1,MAGEA4,TNRC6C,DUSP1,CNOT6L,RASD1,LAMP3,ASB1,HDAC3,MIRLET7D,MIR196B,PLCB1,KCNIP3,MIR383,MIR580,RPL10,MIR148A,ZNF24,SMG8,ZBTB16,E2F6,AQP11,SFN,DNAJB6,NACC2,MIR648,FABP4,DNAJC3,MIR96,IFNA2,CDC73,PAX6,MAD2L2,WNT10B,TXNIP,FOXS1,NMI,ZBTB33,MIR204,MIR577,MIR423,ANXA4,OPTN,UCN,MIR454,MIR887,COPS2,PPP2CB,ERRFI1,MIR1224,HMX1,FOXP3,CD274,MIR589,LMNB1,SPRY1,PRNP,SNTA1,MIR130B,DAPK3,SLX1A,TENT4A,MIR607,SMARCE1,NKX3-2,MIR223,MACIR,MAGEC2,IL6,ID4,TP53INP1,USP38,ZBTB2,MIR379,BAX,TRAF3IP2,EIF4E,SOX21,CHMP1A,MMP9,PYDC2,GNAQ,BAHD1,LSM5,PAIP1,MIR320A,MIR631,MIR1251,PFDN4,RPL13A,PID1,PAK2,MSH6,MIR130A,IL2,MIRLET7B,CAAP1,CCND1,HIRA,PHF1,PAIP2,MIR492,UBE2D1,AR,HNRNPAB,PHC1,TSG101,E4F1,TCEAL1,PCSK9,MIR187,MIR125A,NR1H2,ACP5,PRKCE,MIR450B,CDK5RAP3,MIR10B,MIR448,CLP1,PPP3CA,MIR374A,ELAVL4,MIR182,IL1B,SIAH2,TGFB3,AKT1,MIR569,EXOSC8,TLR6,DUSP26,RADX,MIR595,MIR211,CNOT2,PPP1R11,SPRED1,SAP30,MIR604,IGF1,DKC1,PTRH2,CALR,SKIC8,SIRT7,MIR639,MIR675,MIR331,TCF23,BAK1,TXN,VDR,GSTP1,MAX,TNFAIP3,RBBP4,MIR345,CCND3,MIR877,MXI1,INPP5E,CDKN1B,IMPACT,NQO1,HELLS,KLHL22,HOMER3,SUFU,MIR193B,SUV39H1,MIR218-2,MIR503,MIR212,RBM15B,UFL1,APOBEC3H,SGTA,ZNF668,MIR638,LGALS3,ZNF692,MIR335,RNF139,ZBTB14,TRIM44,IFRD2,MIR195,RPS26,PIWIL1,MIR198,MIR1249,DROSHA,LHX2,TIMP4,PCGF2,SAP18,MIR26B,ITGAV,CNOT8,MIR99B,HSPA8,PTPN1,BAG2,TGIF2LX,PAX9,MIR147A,KLF4,ZBED3,APLNR,IFI6,TLR4,MDM2,MIR671,MIR188,SDCBP,HENMT1,TP53,MAEL,MIR583,MIR1-1,PCGF6,ZC3H7A,DDX5,NCBP2,MIR502,YWHAB,MIR214,MIR17,H2AB1,ZHX3,GJA1,PPM1D,PAIP2B,MIR764,NLRP3,H1-5,FOXC2,CASC3,CLDN3,MIR552,PDCD1LG2,LSM14A,RIOX2,SUPT5H,TENT5C,CDKN1A,MDFI,SDR16C5,MIR16-2,NDN,MIR105-1,NAB1,EID2,MIR338,PHF12,CITED1,MIR301A,RB1,TYMS,DNAJC10,HMG20A,HEXIM2,CDK5,BCL6,MIR615,HFE,PFDN5,HINFP,ITGB8,FBP1,MIR1296,MIR649,EMILIN1,MIR98,TBC1D24,KDM2A,DUSP10,MIR628,PKIA,TNF,SHMT1,MIR9-2,TWSG1,CAMK2N1,HMGA1,MUL1,XCL1,NAB2,RBPJ,BRMS1L,CX3CL1,MIR1298,MIR624,MIR191,PHB1,ING1,PDE12,SOCS5,IL20RB,BEND6,THAP1,OPHN1,IL4,MIR504,NPTN,MIR662,SERPINB10,MYD88,IGFBP3,CD46,MIR149,MIR146A,DGCR8,NKRF,SCML1,ARPP19,TYROBP,MIR661,CPTP,MIR876,MIR101-2,CHID1,FURIN,ZBTB17,MIR760,MIR452,SWAP70,H1-10,ING2,DKK3,USP5,RUVBL2,MIR150,LANCL2,MIF,CCL3,HNF1B,ID1,LILRB1,MIR132,IL12A,BARX2,IRF3,HEY2,BTN2A2,CSF2,PARD6A,MIR1225,KLF12,RNF34,SRSF12,RORB,CST3,MIR3173,MIR942,MIR7-2,MIR605,RPS14,EPHA4,MIR200A,MOSPD1,RTRAF,MAGEH1,SFRP1,MIR302B,FLCN,TIMP3,MIR761,MIR484,CRYAB,AGO1,DUSP19,PPIA,MIR551B,GHRL,RGN,SUB1,CPEB1,CSNK2A1,EXOSC4,HNRNPA0,DHRS7B,IL1R2,AZIN1,SOX9,NDFIP1,CBL,MIR429,DICER1,MIR489,ZCCHC7,SNAI2,IGBP1,CNOT6,MIR215,DLG1,BANF1,IKZF5,FKBP1A,MIR29C,EIF4EBP2,TSN,CD200R1,NR1I2,KDM1A,TRIM29,PELO,MIR339,HDAC5,MIR511,CCR1,IRF8,PRMT2,SAP30L,MIR936,TOB2,MIR558,MIR488,MIR30D,MIR517B,MIR367,MIR25,MIR600,DKK1,SPOCK1,DHX9,RNF8,ISG15,STAT6,THAP7,CCR7,HCFC2,SRSF7,DDX4,ZNF345,HAND2,MIR1226,MBD3,BHLHE40,C9orf72,MIR346,MIR449B,DPEP1,KLHL15,MIR597,MIR192,LRP3,DUSP3,RLIM,MIR370,RERE,OTUD7B,MIR9-1,LSM2,TLE1,MIR100,MIR625,GTF2IRD1,INSM2,TRIM3,BRMS1,IRF1,ITM2B,MIR563,NTRK2,MIR618,TFIP11,MIR551A,CCDC3,NTRK3,MIR296,IFI16,CIPC,TLR8,MYT1L,TCEAL7,MIR153-1,EIF4EBP3,NBN,METTL14,CTNNBIP1,RGP1,SOX3,DNAJB4,PRMT6,MIRLET7I,IVNS1ABP,MECP2,BMPR1A,MIR181C,DRAP1,MIR549A,EXOSC3,UBASH3B,SRSF4,MIR542,EDC3,MIR29A,SRGN,MTMR2,NRDE2,MIR765,PPID,SMARCA5,PIWIL3,SERPINH1,ANGPT1,MIR34C,SRC,MIR148B,HEXIM1,ZNF175,PHB2,POLR2G,SQSTM1,HNRNPK,LEP,TRIM21,MIR601,CD200,ATF4,MIR873,ZBTB5,DYNLL1,MIR34B,TENT2,BIRC5,MIR7-3,IFNG,PRKRA,MEF2A,HOXB8,LGR4,MIR135B,GSKIP,MIR802,CD38,CD2AP,MIR1180,NUDT12,MIR181D,MIR222,ZBTB25,CAMK2N2,TRAF6,GADD45A,SFTPD,H2AZ2,PLAGL1,TRIB1,MIR378A,HCLS1,PSPC1,IRF2BPL,HINT2,PML,MIR141,NFKB1,TERT,MIR491,SNAI3,LRIF1,ARG2,TESK1,EIF2S1,PABPC1,P3H1,MIR937,SETD5,MIR205,MIR23B,CLU,KLF10,PCGF3,MINAR1,MIR599,MIR924,MACROH2A2,RPS7,FCGR2B,NKX3-1,NFKBIL1,ATF3,STK38,MIR653,MAGEB10,SCML2,NR2F6,DUSP22,MIR24-1,SMAD3,SERPINB1,PNRC1,MIR920,EIF4A3,HNRNPD,TAF9,TUSC2,IRF2BP1,ELOC,MIR548C,RTN4,MIR330,MIR651,ABCC2,UBE2B,RGCC,TIA1,SYNCRIP,MSX2,WDR82,ANAPC2,MIR375,CPNE1,MIR519D,MIR21,MIR30B,INHA,SIN3A,IFI27,LYAR,PC,SERPINB9,MIR129-1,MIR593,CD36,BAP1,MIR210,RMI2,FOXD3,IREB2,TCF21,DXO,MIR197,POU5F1,LIG3,MIR33B,SRSF10,JUN,MORC2,MIR186,DMAP1,MIR885,CBX3,LDLR,ENO1,MIR449A,ZNF263,MTA3,MIR10A,SERPINA5,PPARA,YWHAG,MIR190A,THRAP3,FOXP1,IL12B,MIR185,LDB2,PCBP4,MIR1-2,RFX5,SERPINA1,CSK,MIR633,ERP29,USP2,CAMLG,MIR107,SNX12,LMO4,AATF,CREBZF,MIR377,MIR643,H2AC4,EIF2AK2,MIR206,MIR155,MIR221,PLAA,CTDSP1,PHF21A,NCOA5,CRKL,SLC8A1,TRIM24,MIR497,PTEN,MCPH1,MAF1,MIR500A,LRP6,TIRAP,USP3,BST2,MIR573,PKIB,STAT1,CRY1,PPP1R8,GSK3A,DEDD,SMCHD1,CD34,ABCE1,DEFB114,GMNN,MIR578,LMNA,ZMYND11,EID2B,MIR1271,MIR938,MIR136,SERPIND1,NOP53,MIR92B,H2AC6,PRMT5,MIR99A,LSM4,RNF128,MIR9-3,SMAD4,SELENOS,PDCD10,MAGOH,MIR384,DR1,EP300,OVOL1,MIR1227,BACH1,HYAL2,SHLD1,CTNNB1,SP2,CRTAP,GPX1,H2AC7,ANXA7,TSNAX,MIR193A,DCP2,GABARAPL2,ZBTB6,UFD1,TSPO,BTG2,PGR,SLA2,GPNMB,MIR711,SESN2,MIR106A,PPARG,MIDEAS,PAQR3,MIR30A,RPL23,MIR626,PTGER4,EPO,CLN8,NR4A2,AP1AR,SERPINA3,MIR28,RAD21,LSM6,MKKS,CNOT7,GAPDH,MIR422A,EGR1,MIR934,IKBKB,MIRLET7G,YTHDF2,ESR2,MIR554,CHRNA7,EZH2,UPF3B,MIR1262,EZH1,HELT,PTPRQ,MIR340,ATXN1L,FGFR1,NKAP,MIR155HG,PIWIL4,SIX5,PTPN11,MIR590,ENC1,SMG9,TRIM27,DDIT3,DNAJC2,CDK6,NONO,POLE3,MIR586,CXCL8,TAF7,PFDN1,MIR133B,TENT5D,FKBP8,IDO1,SVBP,MIR216A,ZNF451,VPS72,MITF,MIR770,IL13,MIR609,UBE2D3,FHIT,MIR34A,DIS3L,TFDP2,LDB1,AZIN2,XAF1,H1-6,EIF4E2,MIRLET7C,F2,CGGBP1,MIR581,ACOT8,MIR1277,MIR657,PSMD10,INPPL1,APOBEC3B,SPINDOC,H2AX,ZBTB45,FBXW11,ADNP,OGG1,CGAS,MIR424,DAP,CXXC5,DFFA,MIR495,CORO1C,HMGB1,RGS2,EPHA2,VPS28,GABPA,MIR875,AGER,MIR361,ZNF304,HRAS,PYCARD,MIR23A,ADIPOQ,MIR505,LBH,RBBP7,MIR636,DDRGK1,MIR611,H2AZ1,MIR567,YAF2,MIR640,FERD3L,ROCK2,IL10,STN1,SRSF2,RAF1,CBX5,MSX1,TRAF2,MIR145,CX3CR1,NMBR,TAGLN3,NKX6-2,RPS3,PPP1R1B,TRIM6,H1-1,FOXP4,ETF1,ZMYM2,ZMPSTE24,CNKSR3,RUNX1,GFI1,MIR208A,PKIG,BRCA1,MIR31,SERPINB6,SNX3,WWP1,MIR342,SMAD2,SNRNP70,ZHX1,MIR324,S100A11,APOBEC3F,ZGLP1,UBE2I,MTM1,PSEN1,TNKS2,LILRB4,ARB2A,HBEGF,ZBTB42,AP2A1,RBBP8,SOCS3,CAV1,TRIM11,PFDN6,IFNB1,MEPCE,USP8,RC3H2,SMG5,RBFOX2,TNKS,AGAP2,HSP90AB1,CBFB,CD28,VGLL4,CDKN2D,FKBP1B,ZCCHC17,CAV3,BEND5,MEF2C,APOBEC3D,CD83,MIR190B,MIR105-2,APLN,MOV10,SNIP1,CDK1,OSR2,RPS6KA4,MIR194-1,INPP5K,EED,TGIF2,NFIL3,SMAD5,SOCS4,MIR557,H2AC13,MAGED2,CDK5R1,CTDSP2,SPON1,ITM2A,MIR106B,HCRT,WWP2,DLX1,MIR216B,HNRNPA1,CREB1,MIR126,MIR553,MYC,MIR184,TDRD7,HSPB1,MIR490,APOBEC3G,MIR142,DAPK1,MIR556,MIR20A,TADA3,CIRBP,MIR656,TRIM22,CSTB,CSTA,PYM1,MAFG,PICALM,IRF7,NLRP6,USP14,MAD2L1,PFDN2,MIR200C,MIR425,ATP2B4,SMAD1,ZBTB26,XPO5,MACROH2A1,MIR708,MIR1260B,CTBP1,SHC1,ZNF174,HNRNPC,OAS1,TWIST2,SUMO1,TM4SF20,SOX2,PTPN22,GCLC,TRIM37,IRF2,DYRK1A,HSBP1,TPPP,MIR152,PIWIL2,ZNF177,GREM1,MIR940,MIR147B,ZBTB18,MTDH,PROX1,CREBBP,NOTCH2,SVIP,DBNDD1,MIR144,TGFB2,CHP1,CRYBA1,MIR612,RING1,PCNA,NCK1,MXD1,ZBTB38,SPRED2 |
| 8.177e-25 | -55.46 | WDR5 (WD repeat domain 5) | protein interactions | 11091 | 1069 | 452 | 19454 | 5460 |
SRPRA,H2AZ1,HACD3,FAM199X,EIF2B5,PRNP,ZBTB2,ATP5PD,POLE3,AKAP17A,ESYT1,SSX2IP,RING1,THRAP3,HSPE1,LSM4,EIF3E,RPS13,OLA1,CTNND1,ARF4,MRPL11,CCDC47,RPL15,LBR,EEF1A1,SRP72,ILF2,SLC25A20,EIF4A3,PELP1,ACAT1,PTEN,GLTP,RTRAF,PRKRA,SLC25A4,RPL13A,RAB14,TXN,LDHA,ZNF622,RPL22,SEC13,RETSAT,AR,NONO,TUFM,ATP5F1A,TADA3,PRPF4,MAVS,MTDH,NUCKS1,RPL4,HMGB1,GTF2I,SGF29,MBD3,NHP2,CCND1,PSMC4,RPS14,WDR83,CNP,LSM2,HSP90B1,JUP,RPLP0,PHB1,DNM2,TSG101,BUD31,SPTAN1,RPL7,NOP58,MRPS35,STOML2,DPY30,TAF7,PRPF19,PSMD3,PRDX1,EIF3D,KDM2A,TRAF6,AHSA1,UBE3A,INO80C,GNL1,ETFA,G3BP1,RBBP7,PCGF6,EIF2D,RFC3,E2F4,FEN1,MARCKSL1,SAP30,GFPT1,MAK16,MOXD1,GTPBP1,RAN,RPL37A,RBBP4,RPL7L1,RPL19,NOP16,CUL3,GALE,LMNB1,PFDN6,SP1,DHRS1,UNC45A,G3BP2,EHD1,PPP1CB,ADNP,ATP5PO,NDUFA5,MYL6,COMT,SYNCRIP,EEF1B2,STT3A,RPS16,TMPO,DKC1,KARS1,ORMDL3,CSNK2A1,COPS5,RPL10A,RPS2,SLC25A11,IDH1,ABCE1,RPL3,SRPRB,KDM4B,TMEM205,H2AX,ACTR1A,RBM34,SESN2,PSMC3,RNF8,GFM2,RPS3,EIF2S2,PSMC5,ING2,ADRM1,BUB3,GPX1,SRPK2,SUB1,MAT2A,ATP1A1,HCFC2,UGDH,PRDX6,RNF113A,HNRNPH2,KDM1A,HSPA5,ZC3H15,EIF4E,SPTBN1,IDH2,H2BC11,RPA2,ACACA,E2F6,SRSF1,DYNC1I2,LYAR,TCP1,LSM5,EIF2S1,IQSEC1,PPIB,DRG1,CCT8,PABPC1,PDIA6,RTCB,RUVBL2,H1-6,RERE,HNRNPDL,MAX,KIF2A,SOX2,RPL18,MTA2,TACO1,ANAPC2,GTF2F1,SNRNP40,PSMD6,ATP5F1B,PCCB,CHTOP,H1-10,ICAM1,XRCC5,YAF2,EP300,HDAC5,HSPA8,RER1,STAU1,HNRNPA0,MRPS7,SAP18,PAFAH1B1,NUP62,RPL27A,FDFT1,RPL12,PTPN1,RPL35A,MRPS23,TOMM70,SPATS2L,HM13,SFXN1,RAB1A,RPL23A,FARSA,FASTKD5,PAGR1,VTA1,CCT5,METAP2,CTNNA1,ENO1,MRPL53,CCNF,RPS12,COPE,DEK,GNAI2,CIAO1,GMNN,RACGAP1,DNAJC8,MAPRE1,IDH3A,HELLS,RPA3,FBXW7,PDHB,CXXC1,SEC22B,PCK2,WDR5B,KLF12,SLC35E1,STOM,RARS1,RPL9,RPL8,KRT8,RPLP2,BRD9,AGK,DHX15,SRSF10,PDIA3,HMGA1,HNRNPA1,WDR12,SKIC8,HNRNPD,HNRNPA2B1,SLC25A5,HSPD1,SRSF7,PRPSAP1,SSRP1,RPS27A,TMED7,PSMD12,CSNK1E,ZNF263,NAA15,HSDL2,ARFGAP1,RAF1,RPN1,SNRPE,SART3,RPS11,SNRPD1,SNRPD2,ACTB,TUBB,MRPL23,ERH,PRRC2A,TAF11,ACO2,PRPF31,YWHAZ,BRCA1,RPS5,PFDN4,HSP90AA1,PSMA3,PGRMC1,ACTL6A,KLF3,ARCN1,SLC25A3,ALYREF,MRPS9,ACSL4,PDE9A,ADD1,FZR1,TMED9,CAND1,CPNE1,MBD5,MYL12A,CYSTM1,GAPDH,API5,RPL24,H2AC4,SMCHD1,MAP4,PSME1,DHX9,HNRNPK,CSE1L,NUP107,PDE12,NEDD8,H3C1,CHMP1B,TP53,RPSA,PIK3CA,CDK8,CBX3,SURF4,GNAI3,NUPR1,UQCRC2,PSPC1,CDIPT,SF3B6,MACROH2A1,PHAX,CSNK2B,CTSB,UGT1A1,CDC20,RPL7A,SMARCA5,CFL1,CFL2,UBE2H,CDKN2AIP,DTL,OAT,IGF2BP1,PML,NLE1,BAP1,DDX46,HDAC3,DYRK2,FUBP3,SIN3A,PSME2,STX5,WDR82,SNRPD3,SNRPA1,RPS10,HNRNPL,RAB1B,CCT7,HSP90AB1,RAB5C,WWP2,RPL6,PFDN5,DDRGK1,CTNNB1,XPO1,POU5F1,ABCF1,EWSR1,RUVBL1,PSMA1,HNRNPF,RPS4X,ETFB,RPS7,EEF2,PTRH2,PLS3,TUBB4B,TAF10,RPS23,SMARCB1,DLST,VDAC2,ZMYM2,PRMT5,MATR3,APEX1,NCKAP1,RPL10,ESR2,POLR2B,LRIF1,PSMA4,HNRNPC,HNRNPAB,MYC,CREBBP,CPSF2,SNRPB,PSMD1,KANSL3,BTF3,PSMD14,CIRBP,CCT2,H1-1,COP1,DDX39B,DDX5,DR1,SF3B1,PHB2,EEF1G,TMEM177,FXR2,UFL1,TRMT112,CNDP2,CSNK1A1 |
| 1.684e-24 | -54.74 | AAR2 (AAR2 splicing factor) | protein interactions | 25980 | 651 | 303 | 19454 | 5460 |
ATP1A1,SERPINB1,DNAJC10,GLOD4,MTPN,CFL1,RPS17,RPL7A,PSMB2,CARS1,SLC25A1,MAT2A,TXNDC12,GMDS,BUB3,PTPMT1,ABHD14B,CSNK2B,RPS3,UQCRC2,SF3B6,LUC7L3,ACACA,SSR1,RPA2,HSPA5,MARS1,RPS15,PRDX6,PGK1,HNRNPH2,DDX46,RPL27,MAP4,RPL10A,RPS2,SHC1,RPL24,SNRNP70,LANCL2,GAPDH,TPM3,ELOC,CDC5L,IAH1,MIF,FZR1,RPS16,DSTN,RPL32,UBE2N,COX4I1,SDHB,EEF1B2,SYNCRIP,SSBP1,PSMC3,ACADSB,CAPZA2,ARPC3,TFRC,CBX3,RPSA,MTCH2,RRM1,CAPZA1,RPL17,HNRNPK,CSE1L,TMEM33,KPNA2,PSMA5,DHX9,RPL3,SLC16A1,PSME1,SLC25A11,MDH1,SERPINH1,CCT2,SNRPB,BAG3,PSMA4,HNRNPC,LDHB,MYC,RPL10,POLR2B,SNRNP40,FBXO22,MATR3,TAGLN2,ATP5F1B,LMBR1L,S1PR4,VDAC2,TRMT112,RPL27A,TOMM22,LYPLA2,SERPINB6,PHB2,EEF1G,SRSF2,HNRNPA0,DDX5,SF3B1,HSPA8,FLYWCH2,RPS28,PEBP1,SNRPA,YWHAB,HSPB1,YWHAG,XPO1,PPIB,RPL6,GSTM3,CCT7,LANCL1,HSP90AB1,LYAR,SNRPD3,SNRPA1,TCP1,TRIR,RPS10,RAB1B,EIF2S1,PSME2,RPL18,CRKL,RPS23,UCK2,TUBB4B,PLS3,RPS7,EEF2,DHX38,IMPA2,TFG,PRPS1,RPS4X,RUVBL1,VDAC1,HNRNPF,PDIA6,RTCB,EWSR1,RABGGTB,RUVBL2,ABCF1,CCT8,PABPC1,RPL31,XPOT,GMPS,TUFM,RPL26,ATP5F1A,VIRMA,UBE2L3,SLC25A4,RPL13A,TXN,LDHA,MGST3,RPS12,MSN,RPS20,CMBL,GANAB,CTTN,TUBA1B,EIF4A3,ENO1,CCNF,HNRNPH3,RPLP0,RARS1,HSP90B1,CDK1,TIMM23,SPR,SEC22B,SNRPN,EEF1E1,PSMC4,RPS14,SF3A1,POLDIP2,RPL4,GTF2I,CSTB,NCDN,RPA3,KIAA1143,ECD,HDAC6,H2AC14,G6PD,ATP5PD,RPL35A,EIF4E2,HACD3,RPL12,AIFM1,ILF2,GGCT,RPL15,CD2BP2,CCT5,SNRPG,PTGES3,EIF3E,PRDX4,RPS13,ARF4,FN3KRP,HSPE1,FARSA,TSSC4,HSD17B10,RPL23A,SLC25A10,RPS5,HSP90AA1,YWHAZ,MCM3,RAB11A,CUL3,USP5,RPL19,CHP1,CHCHD3,MAD2L1,ACTB,SIAH1,TUBB,DYNLL1,RPL35,STARD7,PRDX2,RPS9,SNRPD1,RPL37A,SNRPD2,RAN,ARF1,RTF2,FKBP1A,MYL6,SLC25A3,ISOC1,ARMCX3,ATP5PO,PRDX3,FTL,SKP1,HSCB,PSMA3,HADHA,TXNL1,RPL23,HNRNPD,HAX1,DDX23,HNRNPA1,PRPF19,PDIA3,PRDX1,DHX15,EGLN3,CACYBP,PPIA,RPL7,KRT8,RPLP2,RPLP1,PHB1,RPL9,RPL8,SNRPE,RPS11,GNB1L,NME1,RPN1,GFPT1,PPP2R1A,FAF2,HSDL2,ANP32A,RPS27A,RBBP7,SRSF7,BAG2,RPS24,PCNA,NDUFA4,HNRNPA2B1,SLC25A5,HSPD1 |
| 2.457e-24 | -54.36 | YBX1 (Y-box binding protein 1) | protein interactions | 4904 | 710 | 324 | 19454 | 5460 |
CUL2,CUL3,IRF1,MIR98,MRPL16,ZNF668,ZCRB1,DCAF4,BRCA1,MIR363,LSM14B,RIT1,EIF3K,SNRPD1,SNRPD2,RPS9,MRPL23,ACTB,SIAH1,RPL35,RPL7L1,RPF1,TUBB,MIRLET7D,UBE2V2,RPL19,H1-5,VAPB,LARP4B,NOP53,GPC1,MRPL57,MIR106A,PIK3R1,PRPF19,HNRNPA1,ZCCHC9,MRPL18,TRAF6,MIR1-1,HNRNPD,IFIT2,PSMB5,PSMB4,PHB1,MIR7-2,TSG101,MIR141,RPL7,DHX15,B3GNT2,RAF1,ACTN4,OTUD6B,EZH2,CHMP4C,NGB,SF3B5,SNRPE,SART3,TRIP4,HSPD1,HNRNPA2B1,PCNA,SRSF7,MRPS11,RPS24,G3BP1,TRIM37,MRPS17,UBE2A,RAD21,FLOT1,RPL26,TUFM,PPP1CC,IVNS1ABP,MIR145,PPIG,MIR16-1,CCNF,EIF4A3,GSK3A,RPS20,NDN,RPL13A,FERMT2,RPL22,VIRMA,ATG16L1,PSMC4,NFYB,MIR1-2,RBMS2,MRPS34,LMNA,METTL14,ZNF574,RPL26L1,RPLP0,RPA3,MIR205,MIRLET7I,SQSTM1,MIR34C,MTDH,MRPL17,MIR7-3,RPL4,FBXW7,NHP2,BRIX1,MRPL20,UTP23,GRSF1,HDAC6,APOBEC3F,MIR34A,SMAD3,MIR106B,ACTA2,KRR1,PRR3,MIR25,EIF2B2,MRPL50,CDK9,MDM2,MRPL24,FBP1,MRPL11,MIR200C,APOBEC3D,MIR15A,EEF1A1,MIR20A,LLPH,MIR17,ILF2,MRPL51,SRP72,MRPL49,FAF1,ZC3H11A,RPL23A,MRPL22,MRPS18C,RIGI,MYC,APOBEC3B,PSMA4,HNRNPC,HNRNPAB,BTF3,SNRPB,FBXW11,MRPS25,FTSJ3,ICAM1,H1-1,NSA2,VEGFA,SURF2,CMTR1,SMU1,MIRLET7B,SF3B4,MRPL13,MATR3,IREB2,APEX1,RPL10,PABPC5,MRPL12,MRPS18A,PAK2,EIF4B,PIH1D1,NGRN,SF3B1,HSPA8,YAF2,EP300,TRA2B,UFL1,STAU1,MRPS7,IFI16,DCAF4L2,MIR143,RPL6,XPO1,MIR29C,MRPL9,CPEB1,DDRGK1,CTNNB1,MIR31,AGR2,MIR221,DDX1,POU5F1,MAGOH,MIR140,SRSF1,MIR214,HNRNPL,RPS10,PAIP1,EIF2S1,SNRPD3,SNRPA1,DYNC1I2,MIR9-1,MACROD1,TOP3B,ISG15,SOX2,MIR222,H1-3,PAIP2B,EEF2,RPL31,MIR9-2,LSM14A,PABPC1,EWSR1,MIR206,KRAS,H1-6,PSMA2,CHCHD2,MIR155,NUP42,AKT1,PSMB2,RPL7A,PRKACB,SLC6A4,MECP2,SPOP,TRIM23,RC3H2,ELAVL2,IGF2BP1,UBE2H,RPS3,SF3B6,FGFBP1,MRPS28,BUB3,MRPS21,SMURF1,CDC20,SRPK2,MIR34B,AGO1,MRPL10,MAEL,CFTR,FGF13,RPA2,MIR21,HEXIM1,MIR7-1,RBM23,BAP1,MIR10B,THUMPD1,RNF113A,MRPL40,MRPL41,MIR107,HSPA5,MIR29A,CMSS1,COX5A,COPS5,CSNK2A1,GAPDH,E4F1,API5,H2AC4,SNRNP70,RPS2,LSM3,SYNCRIP,MRPS9,SSBP1,ALYREF,FZR1,CAND1,RPS16,MIRLET7G,TMPO,MIR429,DKC1,LMAN1,LCP2,SURF6,CDC5L,RPSA,INSIG2,TP53,MRPL47,H2AX,RPAP2,DUSP1,TFCP2,MRPL33,RNF8,MRPL52,MIR200A,MRPS18B,RPL3,MIR9-3,DHX9,MRPS33,NEDD8,HNRNPK,MIRLET7C,MEPCE,MIR16-2,RPL17 |
| 2.802e-24 | -54.23 | ORF6 (ORF6 protein) | protein interactions | 43740572 | 825 | 365 | 19454 | 5460 |
HSPE1,THRAP3,PRDX4,SNRPG,MSH6,ARF4,RNF20,RPS13,HINT1,EMC2,HSD17B10,RAD23B,TBK1,CCDC47,RPL15,LBR,DDX39A,EIF2B5,CAV1,ATP5PD,EHBP1,AIFM1,HACD3,SRPRA,SEC23A,PSMD7,ESYT1,SLC2A1,DNAJC7,CALR,GLO1,RPL4,TMEM209,MTDH,SQSTM1,MAVS,HSP90B1,P3H1,CDK1,PSMC4,TXN,EIF4A3,STUB1,ACAT1,GANAB,IVNS1ABP,CCDC22,REEP6,XPOT,PYCR2,SEC13,NDUFB10,TUFM,NONO,ATP5F1A,ETFA,PCGF6,PLSCR1,JAK1,STIM1,PLD3,MARCKSL1,YIPF3,SPTAN1,CCAR2,RAB11B,ERLIN1,FAM3A,RPL23,AHSA1,STOML2,PRDX1,EMC6,NSFL1C,SKP1,ZDHHC17,PSMC1,THOC3,HADHA,MTX2,WDR77,RAB6A,PRDX3,RPL35,CHP1,CHCHD3,CYB5R3,FAU,SLC30A7,AP2M1,LMNB1,ELMO2,MCM3,TOMM40,RNF40,TMEM33,SRPRB,FKBP8,CAPZA1,RPL3,STX18,ARPC3,TFRC,PSMC3,TAB2,IPO8,UBL4A,PREB,ACTR1A,UBIAD1,DNAJC1,ARL6IP5,TMPO,COX4I1,CAMLG,SYNCRIP,SNRNP70,USP15,RPL10A,RPS2,PGAM1,KARS1,HSPA5,ZC3H15,PRDX6,SAMM50,EIF2B3,SPTBN1,ADRM1,PSMA6,SGTA,STX10,PSMC5,EIF3G,SNX5,CALU,ATP1A1,MAT2A,RPS17,NUP42,VDAC1,ZNF609,POLDIP3,RPL28,PABPC1,GLE1,CRKL,RANBP1,TRAF2,TCP1,DYNC1I2,EIF2S1,VAMP7,CORO1C,FKBP4,NT5C2,RER1,PRCP,HNRNPA0,XRCC5,AKAP1,UBAC2,TMEM115,FDFT1,TANK,NUP62,ATP5F1B,PSMD4,ATP6AP2,EFHD2,GCC1,SLC38A1,TMED5,HUWE1,SMN1,PTGES3,TMED1,SIKE1,RPL23A,NDUFS3,CMPK1,SEMA3C,COG1,PTPN1,RPL12,PSMB1,NME2,OSBPL8,HM13,YKT6,PDHB,SPCS2,GOLGA5,STOM,HNRNPH3,ARHGAP1,SEC22B,RABL3,CCNA2,SLC35E1,PDCD5,ARFGAP3,AP2A1,HMOX2,ATP5F1D,PSMD12,RPS27A,HNRNPA2B1,SCD5,GDI2,RPN1,SNRPE,ANP32A,MACO1,IFNGR1,ERLIN2,FAF2,ACTN4,PPP2R1A,AGK,DHX15,WDR44,NUP35,PSMB4,RPL8,ATP6V1A,PPM1B,HAX1,HNRNPD,RAB32,PDIA3,HNRNPA1,CCDC186,YTHDF1,EXD2,PSMA3,RABAC1,VAPB,PSMB7,ARCN1,PGRMC1,NOTCH2,TOR1AIP2,NDE1,REEP4,RPF1,PRDX2,RANBP6,USP5,TRMT6,SEC61B,RPS9,SNRPD2,HSP90AA1,SCFD1,CNIH4,RPS5,PYCR1,TM9SF4,CDC123,RPS29,MRPL16,PRPF31,CSE1L,HNRNPK,RHBDD3,AKAP12,PSMA5,MAP1B,YIF1A,DHX9,RPSA,ATP5PB,YIPF4,GTPBP8,RPS27L,CAND1,TMED9,LMAN1,RPL24,AKAP8L,PCYT1B,DHRS7,ELOC,AIF1L,RPS15,CLU,GRPEL1,TEX264,RPL27,DLAT,DERL1,ARFIP1,PGK1,SSR1,LEMD3,CYC1,NECTIN2,SF3B6,SEC61A1,ATP1B3,PSMB2,SLC25A1,SUGP1,GORASP2,ARHGAP21,CFL1,HNRNPF,PSMA2,PSMA1,TFG,RPS4X,MYO1B,PDHA1,RPS23,APTX,EEF2,NUP37,RPS7,OSBP,SNRPA1,SNRPD3,HNRNPL,RPS10,RAB1B,HSP90AB1,STX5,CRTAP,AK2,UBFD1,PEX3,RPL6,DDRGK1,XPO1,PHB2,NDUFS2,SRSF2,RPS28,DDX39B,PEBP1,SF3B1,PPT1,EIF4B,PSMB3,BET1,NDFIP1,MATR3,RPL10,PSMB6,CBX5,VDAC2,MRPL13,PRMT5,PSMD14,CKB,SERPINH1,ZMPSTE24,RPS26,PSMA4,LDHB,UFD1,SLC30A5,SNRPB,SLC1A3,PSMD1 |
| 3.485e-24 | -54.01 | desmoplastic | COSMIC cancer mutations | desmoplastic | 14779 | 4434 | 16828 | 4835 |
TMEM91,SLC43A2,ZCCHC9,TOP3B,TEX12,B3GNT2,HIGD2A,MRGPRX2,GRIA2,LRRC24,FLYWCH2,LIX1,KLK5,CAB39,DDX4,PCGF3,GPX5,GDE1,TMEM14A,CDH8,CPSF2,TAF5L,MYEF2,PNPLA8,GLT8D1,UQCR11,NGB,MOV10,AKIP1,SOS2,PIWIL2,PGM2L1,ROGDI,SLC23A2,GYS1,ELSPBP1,STX18,SLITRK2,FOXN2,RBFOX2,CDKN1A,GK2,PPFIA3,SDHAF2,MED11,CLIC2,RBMX2,NDE1,AMY2B,LDHAL6B,CCDC65,HMBS,TDRD7,CD2BP2,ACTL6B,FAM168A,LY6G5C,UBE2D1,SNIP1,SLC4A8,ZBTB45,ABHD13,HRH3,RAB1B,INHA,RGS5,RPAP2,PLEKHJ1,MLF2,TIMP1,DERL2,TXNL1,IL6ST,TMEM59,RPL23A,LYNX1,EIF4B,SLC25A4,PTHLH,MRTO4,SMAD3,PPP2R1A,STK38,TIMM10,AP1AR,PCDH19,RAB5C,PNP,WEE2,RAB37,SLC6A11,FOLR1,CAV2,PSRC1,IFI35,FBXO25,CSTF2T,C1QL1,CRBN,CD226,VPS33A,SACM1L,B4GALT3,PDYN,ZFP1,BEND5,SNRPA,CMPK1,CTNNA1,RAB2A,GPIHBP1,WDR44,TRAPPC6B,CCNF,VAMP2,FN3KRP,WIF1,DYRK1B,PHYHIP,STAT6,SNX24,ACADSB,ISG15,INPP4A,KCNIP3,ARCN1,EZH2,FGFBP2,RAB9B,AMT,NFKB1,PRKAG1,HNRNPK,LHFPL2,ACAP2,SCD5,MAFG,EGLN3,CLDN22,FOS,DYRK2,RIOK2,MRPS28,POMP,RPL26,TPPP,RFTN2,SLC35E1,RB1CC1,CAPZA2,CCL8,YPEL5,PPID,HNRNPA2B1,GGCT,RCBTB1,ATP6V1C1,FANCG,OR2A25,STX6,PLA2G15,MAPK1IP1L,RHOJ,CBLN4,WWP1,TMEM50B,IFNG,JUN,CD47,HIRA,S100A8,SUMO3,ZNF687,CCR3,CMAS,RAB23,SFT2D2,PTGER1,TNFSF18,PPDPF,DNAJC8,RAB33A,CRYGD,FAM107A,RNF167,TNRC6C,SPTBN1,GNPNAT1,GIMAP2,TOMM40L,FERMT2,EIF3J,UTP23,CHI3L1,RNASEL,RFXANK,TRAM1L1,PLAGL1,SESN2,KLHL15,UPF3B,RABL3,ISCA2,ZNF576,GCA,PPP1CB,TRAM2,MPV17,FCHO2,CHST1,EHD1,ZNF609,SELENOS,TMCC2,KCNK10,SLCO1A2,SRP14,TMEM106C,KRT7,PLEKHA8,MANSC1,WDR3,GJB2,CRYBB3,TAS2R5,TMEM203,FOXS1,PTRH2,ACTR2,SYNJ2BP,ACP6,TMEM164,BICD2,CREB1,SERPINA5,KIAA0408,RNF122,RBM12,RPP25,RAN,GLIPR1,SQSTM1,FMO2,TMEM177,HSPA14,CXCR4,NPY5R,POLR3B,BRD9,PGR,HAND2,KCNH1,CCL17,KIAA1191,GTF2F2,DLG4,DDX42,SLC7A14,GMPPA,CYB561D2,MT2A,PPP1R16A,PXMP2,ATP1A2,CLDN8,CXCL14,ADAMTS1,TUSC3,RPL6,BNIP3L,COL1A2,RMI2,SMU1,SLC35D1,CSGALNACT1,R3HCC1,SAT1,EDEM1,GNG2,METTL14,VAMP5,MBL2,MAP3K11,PTS,TOR2A,JPH4,AMIGO1,ERH,ALKBH5,ADIPOQ,ANKRA2,CRTAP,LCP2,UHMK1,TFCP2,CLDN1,ABHD6,METTL2A,CTDSP1,CCNB1,FAM162A,CRYBB2,NDUFAF4,AKAP14,TGIF2,GREM2,POPDC2,GPX6,HTR1F,PDCD4,GPAM,LDOC1,PRPF19,CREBBP,RDH10,TRIM54,ACBD7,FAM98A,CDC42SE2,RPLP2,ZNF287,TMEM184B,KDM4B,ACAT1,RUVBL1,SDF2L1,CXCL3,GTF2B,NKIRAS1,GIT2,CLDN4,LAMB2,SLC13A5,RAB3D,GPR137,SNX17,BCS1L,APOO,TMEM144,TOP1,NRSN2,F9,NKX3-1,GCNT3,MYO6,NDUFS8,CYP2C18,GPR65,SEC61B,TOM1,BCL7B,HTR5A,TMX3,DNAJC22,EIF2B3,CHGA,GBE1,TCF23,ATG4A,SYP,ZNF862,CSRNP1,MRPS23,FUNDC2,RER1,FCN2,RGS7BP,CDKN2AIP,SFRP4,GPHN,ISG20L2,HSP90AB1,POLE4,CIDEB,ARMC7,ATAT1,IPO8,TMSB10,DSTYK,AIF1L,ZC3H7A,ZBTB5,TMEM123,SPECC1L,NAT2,KHDC1,RINT1,BZW2,OR10G9,TSPAN5,ZBTB17,BCAP29,FABP7,CD274,B3GALNT1,CREB3L4,EIF3K,SNAPC3,BLOC1S2,SNCG,IGBP1,AKAP12,SSU72,DDX39A,RAB40AL,TMSB4X,TRIM5,EIF4E,LHFPL4,COX4I2,CDKN2C,RNF113A,EFNB1,PREPL,THTPA,SH3GLB1,TSPO2,GOLGA7B,CSNK1A1,ITGA6,PELP1,COMMD8,TFE3,IFNA10,DEFB114,MT1M,FUT9,PHYH,RTKN,NTN4,RPLP0,UBE2V2,IL10,GMPPB,CALHM2,ADO,CCDC25,TES,LMNB1,BECN1,EMP3,CHMP2A,VMP1,SLC19A2,CBR4,MSMP,HSPA8,B9D2,EWSR1,PROS1,TMEM204,EED,MRPS16,ABHD14B,ELP3,YAF2,TRIM24,MRFAP1L1,ACSL4,TGFB3,CIB2,MTRF1,ZNF592,ADPRH,PDHA1,MBD5,NOS1AP,BCL10,KCNMA1,RGS2,STMN2,NME1,DUSP19,NPR2,CDK4,NR1I2,CNNM4,DPY30,BRCA1,PCDHB1,ABHD4,TRAF2,RBM7,KCNK13,STAU1,TSN,STOML3,RNASEH1,DNAJC3,TMED7,KLK6,FKTN,SLC41A3,SERINC3,DERL1,IL18,CSNK1A1L,SOX2,ST3GAL1,IRF3,MTHFD2L,KLC2,STXBP1,PAX9,PCMTD2,PRKAB1,DPEP1,UQCRH,STK24,LCA5,RAC2,LRP6,TAS2R40,PYROXD2,MRPS21,SLC32A1,PARP11,ZNF501,CEP97,IFRD2,ST3GAL5,POR,NFIL3,ZBTB38,HECW1,TRIM37,PTPN1,SETD5,HNRNPC,RMND5B,RBBP7,SLC25A21,PGS1,ACTA2,SIX5,TRIM21,ARMCX2,SPR,GALNT12,ARFIP1,PPARG,ZDHHC14,ADRB1,PKNOX1,FRMD8,RFX4,HEY2,PCDHB8,RBM17,FAM199X,NIPA2,RABL2B,CLDN11,TRAPPC1,SPTAN1,SLC35E3,RNASET2,NPY2R,LRP12,CIB3,TACR3,PRMT2,CAMK2G,BUD31,TMX4,SRP54,CCDC47,TTC4,SCFD1,GHITM,CACNB4,TUBG1,RPL15,CAMK2N1,HCRT,FGFR1,SHC1,PYGM,CCDC127,PEX3,RCVRN,FAM89B,KCNJ11,CRYGB,PPP3CA,CD200R1,CCT5,ENPP4,MCOLN1,PSMB5,SORD,SBK2,AGK,ANAPC2,FBXO32,ZNF593,ARMCX5,PRPF4,IMPACT,CD58,AGER,IDH2,FKBP14,RAB18,RARRES2,KPNA1,CSNK2A1,PIWIL4,KBTBD2,GSTO2,ATF4,GNG7,CTNNBIP1,JOSD1,SUPT7L,KIT,RS1,LSM3,AFTPH,S100A6,DYNC1I2,CYP27A1,ZYX,UBAP1,CDC73,LHX2,MMP9,BTF3,SNAP91,MYH2,HEBP1,SLC7A9,ALKBH4,PGK1,ROPN1B,VRK1,TMIGD1,DNAJC5,FZD4,MEST,WDR77,MTPN,ATP6V1G1,LYG2,MFSD6L,MX2,GPBP1L1,ZCCHC10,SYN3,AAMP,FBXO42,TMEM215,ZNF24,TSEN54,SERPINB10,FGF1,INO80C,HBE1,ABCB1,AZGP1,PSME2,AZIN1,CCL19,TBC1D10C,NKX3-2,MAGOH,GTF2E2,MLF1,LBH,JAK1,NDST1,TNFAIP8L2,DEFB116,DHRS3,RAB3B,CDCA3,SMAP2,KTI12,SENP5,IDH3B,CYP11B1,CTNNBL1,GRM2,TLR3,GPAA1,JAKMIP1,CYP39A1,HSD11B1,MYL12A,SWAP70,FAM8A1,ITK,EIF4H,NCR3,CHDH,GNRH2,ENY2,RAG1,IMMP2L,MEF2A,DHRS4,SLC35A1,MRPL24,MRPL50,ZNF304,SNAPIN,SLC30A5,KLK3,IL15RA,SLC38A9,RMND1,MIOS,FAM78A,PPP1R2,CCT2,ATP6V0E1,UBE2D3,UBE2A,ARMCX1,IRF1,ING1,STRBP,NAIF1,TRIM23,NHP2,LTBR,GAL3ST1,CASK,FGFR1OP2,GABARAP,PRPSAP1,GRPEL1,TCP11L2,ELMO1,GLUL,CNIH4,CDK5R1,NRP1,NCKAP1,ATPAF2,KIAA0232,CLU,LMO4,SLAMF9,ZMYND19,TAAR1,CCR6,ID4,ZNF319,SEC14L1,APOBEC3A,ZNF397,XAGE5,ATP6V0B,TMEM219,EDF1,ZNF207,POLR3H,C1QC,TRIM3,TMUB1,SLC17A5,ZNF671,SLC25A31,UGCG,MEAF6,LYPLA1,RPS14,LIG3,KLHDC8B,RNF141,ARHGAP1,DOK4,PLA2G5,KLK9,PDIA6,UBR7,SDR42E1,CD99L2,PRIM2,SNRNP27,TRIM32,E2F6,ZMPSTE24,EXOSC1,EFCAB7,GPR89A,MRPL23,GDI2,GFM2,GSTO1,TMEM156,GALNT1,AK2,SOCS5,PSMA3,CCDC69,MRPL13,EHBP1,MGP,MDM2,LYAR,GNRHR2,TOM1L2,EXOC8,PFDN5,UST,RND3,CNP,NUDT3,B9D1,CRABP2,DPP10,PRRC2A,SF3B4,DKK3,IL20RB,CCNI,PPIL4,RAB11A,CDO1,L1CAM,SNX20,WDR38,FIBIN,TLR9,COMTD1,FNDC8,APEH,FGD2,DLX1,AKT1,INPPL1,KIF2A,BACH1,MIA2,CCDC42,FCAR,NPTN,POU1F1,CYC1,PTDSS1,ID1,SLC35A2,ARMC8,ENTPD4,DEGS1,CRYBA2,SCAMP2,SPEF1,SLC5A6,PRKD3,CYP4F8,NLGN2,DEK,PPIB,BPGM,CDKN3,CD164,AKR1A1,SPATS2L,NOP58,NFE2L1,RBCK1,MRPS25,CTSD,PGAP2,MRGPRX4,FABP5,PWP2,RAB3C,MTAP,CTSK,CACYBP,URM1,CETN3,NFYA,S100A10,FAM200A,STX8,DUSP1,TGFB1I1,TOLLIP,BATF,ANP32B,CHST9,CPT2,NDNF,AP1G2,LCN6,SETD4,OR2W1,RPGRIP1L,CCND1,WFDC13,TMED3,ACOT13,FBXO9,COX7A1,AP3S2,TMEM33,MRPL47,S100PBP,MPHOSPH10,KLF10,FAF2,BMPR1A,RHCG,SPINK13,ARHGAP21,SCG2,SYNGR1,ZMAT5,RTP4,LSM6,PRKX,FGF13,PROX1,ENPEP,NAB1,SLPI,USP39,CERK,ZNF174,USP38,DCAF5,ESR2,CWF19L1,CDK6,SNRPD2,ADCY3,SFTPD,CLEC12B,RAB8B,CTNNB1,CYP2D6,SOCS2,INTS12,RAP2B,ABHD16B,TNFAIP3,MMACHC,TRAF7,DUOXA2,MTMR12,SIRT7,FYTTD1,NOL4,IQSEC1,TAPBPL,ETV6,RRAGA,SPRED1,H19,TSSC4,ALDH1L1,MAK16,POLL,NONO,TCP11L1,SOST,SV2B,HPCA,OR2A2,EIF4EBP2,GFOD1,SIVA1,SNTA1,SNAPC1,GPR37L1,NDUFAF2,GAS8,CHRNA7,KIF1C,CDKL2,CD3G,BRMS1,IPP,NQO1,TBCE,SPATA2L,LMBR1L,AKR1C2,IGFBP4,NPVF,TAC1,RBM23,TMED1,ADAT1,HEXA,BRI3,TRMT6,PTCRA,CXCR1,NEDD8,HBB,FGF17,KCND2,CCL21,NDUFA5,ST13,LPXN,RASGRP2,IL34,DFFA,RAP1A,ACAA2,UCKL1,RABAC1,WWP2,FBXO30,TIGD7,CD2,POLR2I,EIF1AD,NAA11,ISYNA1,NDUFB8,APH1A,FRA10AC1,PDIA3,XPOT,WNT7A,LEPR,STX17,RPRML,MSX2,SNAI3,PELI3,CDC37L1,KRR1,NLE1,HSPE1,CLDN14,ZKSCAN1,SIPA1L1,STAMBPL1,PGBD2,SERPINH1,RPL37A,HADHA,LEAP2,DHX16,SOX21,RAB4A,TRA2B,NUDT16,GXYLT1,B4GALT6,KCNA2,HSPB1,LHFPL1,EIF2B5,SH3GLB2,GALE,CXXC5,ENDOD1,CIRBP,UTS2R,NEK7,PHKG1,LASP1,SPOCK1,FUT8,WBP2,GTF2A1,CREBL2,TXNIP,AQP4,CCL25,GNMT,GLE1,ZSCAN1,EIF4EBP3,WDR37,IL23A,PSMD6,SLC39A9,DHX9,FURIN,PFDN6,LDHA,NUBP2,UBXN10,PCDHA5,SLC20A2,GSK3A,PRCC,NUDT19,RANGRF,ABCC5,THOC1,DNAL4,FATE1,ATP2C1,RC3H2,EEF2,THRAP3,GJA10,EFHC1,SLC25A32,XPO1,EXOC2,XPO5,INTS10,SURF4,TF,CREB3,RNF103,GPR162,APOBEC3C,RNF187,ZMYND11,SLC7A4,ZNF513,WNT10B,DGCR6L,FBXO11,RBBP9,SPSB1,NTNG2,LRRC8D,ETFB,VIP,MIF,RBM15B,ZNF189,EEF1B2,C1D,TFDP2,ZNF22,ACTR3B,SPINT2,ZNF688,BCL2A1,TMEM45B,AP2A1,APTX,HRH2,DUSP22,SOD3,ADAMTS20,GFOD2,YWHAH,MRPL49,GABRB3,FAM187B,PLCL1,MTMR2,ICAM1,DNAJC7,CD83,RPL12,KCTD12,UQCRQ,TMBIM6,CCT8,LSM2,GGPS1,TSPAN11,MND1,IPCEF1,HMGA1,SH2D5,FOXI3,UTP6,ZNF177,ZNF652,HSD17B11,C1QTNF1,AUH,TTC8,TFRC,ZNF267,IDE,RAB3A,SMYD3,DDIT4,LCN12,FAM91A1,CTNND1,NMBR,LGALS3,MAP4,HHIP,LUC7L3,YIF1A,CA8,TMEM60,CHN2,HBEGF,CALU,AIF1,HAX1,LRRC20,EGR2,RPS3,FOXJ3,RAD23B,USP30,UFM1,GPR146,KCTD11,CLEC7A,APPBP2,ARPC2,ZHX3,IL7,SRSF4,NECAP2,EXOSC3,SH3BGRL,PID1,MYL12B,GINS3,FGF3,DRG1,ERLEC1,CEP85,SRPRB,NDP,TMEM42,SNX33,MED23,USP13,SDCBP,CNTFR,KRT222,PDP2,SMNDC1,NEURL2,POLR2D,SNX12,IL12A,RHAG,TLR1,CAPG,SAR1B,CHORDC1,ANAPC16,ZBTB16,BRMS1L,HCST,FBXO34,DHRS1,WDR55,RALA,FTHL17,F11R,ADK,G6PD,EXOC5,SYBU,SERPINB6,NAA15,PTGES,ACADS,RNF128,PPP2R5A,VASH1,TLR7,GAPT,SERPIND1,CHST7,CRYL1,RPL24,ENO1,GNPTG,RASL11A,CLSTN3,TBC1D19,RGS6,CSTA,ELOVL6,ALOX5AP,TFPT,ZNHIT1,MECP2,PRDX4,SLC25A14,POP7,STYK1,RNF181,DCAF4L2,RPRD1B,SNRPN,TSPO,LYPLA2,PHF21A,COX5A,SLC1A2,THNSL1,RHBDL3,TRMT61A,CAMP,GPD2,CELA3B,FBXL7,LBR,CYP11B2,ZBED3,DAG1,DUSP6,MTHFS,PPIF,SETD7,TXN,MAF1,RPS12,CYB5D2,TAX1BP3,ZNF790,RDH12,CALY,TNFSF12,GABPB1,SCGB1C1,ARF4,SERTAD3,MT3,EIF1B,PML,GABARAPL2,DNASE1L1,PSMA4,PKIA,TRIM35,TRAFD1,PPM1B,SENP8,STX7,MGST2,GADD45B,HBA1,NECAP1,LIMS2,MZT2B,GPC4,PRDX6,AP2M1,TAX1BP1,KIN,TP53,NFKBIL1,CRELD1,INMT,TOX,PTRHD1,IRF8,KPNA6,RWDD4,BET1,CYB561,FCER1G,SLC25A46,TMED4,HEXIM2,TBC1D17,HSD17B1,TSEN34,FTSJ3,GSTM3,SYNDIG1,FTH1,SNX1,SLC35F1,PSEN2,CCM2,ALB,PIWIL3,IL2RG,TNFAIP8L3,SLC48A1,CDC42,DUSP10,BACE1,SLC38A1,VPS16,ACO2,CLN8,SYK,SLC25A26,CPSF4,LCN8,AGA,CD63,AGR2,CACNB3,PCBD1,TTC23,NLGN1,TMEM174,MORF4L1,PSMA6,PCSK9,KBTBD3,AKAP1,CLEC1A,DNAJC24,SLC6A3,CASC3,CNKSR3,TCF21,CALML5,VAPB,PNMA1,SP2,HEBP2,PSMG3,GPR173,TOP2B,GEMIN8,RPS9,TIRAP,MYL6,SEC23A,TUSC2,CCL28,MKLN1,SHISA2,KCTD10,RAB35,MAB21L1,PPP1R8,TMEM50A,SMG8,MYC,LILRB4,CD40LG,SEC11A,FEM1A,VPS26A,CMTM6,EEF1E1,ZNF704,PTPMT1,KBTBD6,FARSA,UBE2H,CD86,MANBAL,PNMA5,PSENEN,SLC2A8,ENO2,ZC3H11A,CCL27,HTR1A,TMX2,SFRP1,WSCD1,ELF1,GOSR2,SLCO1B3,FGF23,CYP2R1,SLC25A39,CD14,PRR5L,G6PC3,RANBP6,DPM2,RNASE6,TP53I3,RNF40,RPS26,DDX1,KDELR2,DAP,KLHL3,CFL1,BRIX1,IRGQ,S1PR4,TNFAIP1,FAM169A,TMEM11,PPP1R3C,CRADD,KCNAB1,AGTRAP,SEMA5A,MCMBP,APBB3,LAMP3,MATR3,REEP6,CHPF,CNOT6,PPY,CRYAB,ROMO1,GNL1,ZNF473,KIAA1143,SELL,ATP1B3,DNAJC2,GNB1L,WDR82,TLR10,ZBTB25,CD28,NAB2,FXYD6,RNF11,CYTH2,SYNGR2,APOC4,TAF7,NLRP2,MRPL53,HDAC3,RPL29,GLRA2,MAP1S,BHLHE40,PI16,LRRC4B,TOMM40,GREM1,FABP4,COX4I1,MPHOSPH6,ANAPC4,ARPP19,GDPD3,ACVR1B,FAH,CTDSP2,RPL10A,SDC2,CARHSP1,NPC1L1,TIMM8A,KLHL9,DNAJB4,TXNRD2,C2CD2L,RAD21,RAP1B,SNX14,AIFM1,POLR2G,COQ10B,ACTR1A,LAT2,FITM1,TMPO,UBTD1,MAD2L2,COX6A2,POLR3GL,RBBP4,FAS,ATF1,ABCB9,CUL3,COX16,ARMCX3,RBP5,EIF3D,DNAJC4,ERVFRD-1,AKT3,POLD4,MAN1A2,CCDC92,SKA1,GRB10,ELOVL4,CHMP2B,API5,RPL9,TST,RNF5,DGCR8,FKBP1A,SRXN1,DNAJC30,EHD3,MRPS18B,ST3GAL4,ZMAT2,NT5C2,DOLK,SAMHD1,C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,INSIG2,LHB,CBL,NCALD,ANGPT1,COPS4,ZGLP1,KCNK17,KLHL23,HSDL1,ACOT6,IL12B,WDR6,MRAS,RALYL,DDI1,RAB28,COX17,ELK1,FAM168B,CYP1B1,MDH1,ATP6V1G2,RAB6B,MMP14,MRPS35,UCK2,LMBRD1,SRSF1,SLC31A1,COX6B1,ITGA2,PRPF18,IGSF21,CDK2AP2,FGF7,MAPRE2,CAV3,EPHA2,TSPAN7,IFT52,ACOX1,F7,FADS2,PIK3R1,DCLRE1C,OR2J3,G3BP2,EXOSC8,ZNF574,POLD2,KLHDC8A,KDM2A,SUMO1,SAP30L,RNF146,FAM76B,SNAP23,PDIA2,CCAR1,NTRK3,PICK1,TSSK1B,GGCX,ELOF1,IRF2BP1,CSE1L,UBE2B,ACHE,GUK1,AGAP2,STX1A,FBXO3,CLDN6,CAPZA1,FAM3A,STAC3,MNAT1,FMO3,TNFSF10,CDK5RAP3,NEK9,VAC14,SLC25A42,CLIP3,CBLN3,CRYGA,GRIA1,YES1,GAPDH,UBL4A,GKAP1,PI15,HECTD3,FGL2,HDAC5,JRKL,RFC5,IDH3A,TMEM97,NSDHL,MED13L,MFSD6,POU3F4,MADCAM1,ASRGL1,MPST,PSMC4,NEO1,PCCB,HSD17B3,ESAM,SLC35C1,RLN3,ANKRD50,BLVRA,RAB32,PITPNA,CRYBA4,CRYZ,FOXC2,PCBP4,MLH3,APOBEC3B,BMPR1B,HS3ST1,TULP3,PSMD1,BARX2,MPP1,RANBP10,SRM,MED27,ADH1B,VPS39,MYLIP,SUPT4H1,FAM174A,SART3,PTPRZ1,IFI16,CLP1,CLPX,CFTR,INA,ATG3,CDKN2D,GPR37,ESD,ATP6V1D,VWF,PSMB10,CDK17,ART5,TMEM39A,HDAC11,SIGLEC5,ATG16L1,DIRAS3,TP53TG5,TTLL10,GJB1,GCHFR,PCYT1B,CSF2,KRT8,PRELP,CHCHD2,SKP1,ZNF200,IZUMO2,TPST1,AGGF1,LCP1,HNRNPH3,RWDD1,SLC25A3,COPE,RBM41,LSM5,DCTN3,IRF2BPL,PRKCB,HCFC2,RPL4,RGL1,SUV39H1,DYNLRB2,CKS1B,HBP1,PIGC,ARFGAP1,MVD,STK38L,CYP4F22,PREP,CDC26,SHC3,SRP72,SLITRK1,DDIT3,RPL28,HCFC1R1,CACNB2,FIS1,EDEM2,SLC39A10,MCCD1,HM13,PGAP3,MB21D2,LCN15,VCPIP1,CCL24,SNRPD1,JUNB,ALCAM,UFSP1,PTPN5,RNF182,RELL1,TIMM17A,SMAD9,LIPA,MARCKSL1,SLA2,IFNAR1,SDR16C5,HINT1,TNPO2,THOC6,PYCR1,CCL11,RAB9A,RXFP2,RPAP3,LYPLAL1,HSDL2,SMG5,RNF139,PLP2,ABCF1,DUS4L,DYNLL1,SPATA4,CMTM7,TBC1D16,CA12,SLC7A1,ADRB3,FMOD,RAB11B,STX5,ARL6,CCND3,IRF4,CSRP1,LEMD3,MAP3K3,ARL11,FHIT,ARGLU1,EZH1,RNF7,TECR,MRPL16,LAMTOR2,SLC41A1,PNRC1,UBE2I,UCP2,TMEM106B,MED29,MFAP1,MXD1,GLIPR2,SPCS1,TDP1,MID1IP1,SNRNP70,SERINC1,PLEKHF2,DICER1,SLC6A7,MAGEB1,IL21,RPL19,HBM,MSN,POU5F1,FGF16,ZNF362,SLITRK5,DDIT4L,SAP30,RNASE4,PDZK1IP1,PDE6D,OR5K1,S100B,TNIK,LRFN3,UBE3A,ZC3H14,CBFB,EFNA5,ASPM,ZC4H2,CETN2,TADA1,PITHD1,SMARCE1,SH3BP4,LEP,RIT2,CACNG3,DOK5,DCTN4,SEC22A,MAP2K3,CXXC1,RPL7A,LSM12,FIG4,MRPL12,FGR,RCHY1,SPHK2,ZDHHC24,B3GALT2,PPT1,ARF6,BTBD10,LRRC14,ZBTB26,EMILIN1,PDCD5,PRDX3,PHF7,MRPS26,HMGB1,CKB,TUBA1B,THAP6,ARF1,ZMYM6,EIF2B2,GNG11,KCNIP2,SERTAD1,ZHX1,HNMT,FA2H,ERRFI1,PHTF2,ZCCHC7,PPIL3,DPAGT1,CTSA,LPCAT3,GPR83,LYRM2,FBLN5,FOXD3,MAEA,ZNF345,KIAA1958,EID2,CXCL10,SMUG1,SVIP,CDH7,ASCC1,ZNF770,TPD52L1,DUSP18,UBXN2B,SEC61A1,TTR,GAD2,METTL18,RSBN1L,COX7B,CDC42SE1,BGLAP,RGS1,SDHC,ASB11,FAM83A,NOL12,RHOG,ST8SIA4,TMEM220,TMEM168,CD200,SIAH1,STRADB,LRP3,NCK1,PLEKHF1,AHSA1,ZBTB6,KCTD16,SLC15A1,TRIM62,ZNF655,TEX19,HNRNPAB,GPR78,CMBL,CDKN1B,TAF9,MEA1,SCHIP1,PHOSPHO2,RFX5,TMEM198,TRAPPC2L,MAT2A,NMRAL1,GDAP1L1,SSBP2,PDCD10,LRRN4CL,ZSWIM7,RPL31,WTAP,HAS3,PRPS1,TSPAN3,BAD,MGST3,UQCRC1,NOC4L,CRHR1,AKR1E2,RSL24D1,TRAF1,CLK1,SKAP2,SERPINA3,KCTD20,RASSF4,ZMAT3,BRS3,NETO1,CDR2,PTGER2,C9orf72,NAA30,PSMB4,HERC3,DOK6,SEMA3C,LSM4,IRF9,HSD17B8,DDX39B,CGRRF1,ANKH,YKT6,VPS26B,ESYT1,F2,ARL5B,HAPLN2,SAP30BP,EDC3,AANAT,LDB1,TRAPPC3,CSRNP3,NRGN,GMDS,WNT2,BIRC5,MFSD3,DTL,PSMG2,TNFAIP8,ABHD2,ARL6IP5,ANKRD46,CEP70,CTDSPL2,SNRPA1,CCDC22,KDM1A,NDFIP1,FKBP2,PRSS35,UNC45A,TBCEL,CYP26A1,GMNN,RALB,ISG20,NUDT1,TMEM87A,TIMMDC1,SERPINB9,MT1X,UBE2V1,SNX11,RPLP1,PDE6A,IMP4,TRNP1,HELT,GFM1,SSH3,HOXB8,SEC61G,CENPM,EMX2,RETSAT,POPDC3,SLC7A11,MET,FZD6,ADIPOR1,PRM1,GAL3ST4,ATF3,CTLA4,RBM5,RANBP1,ACSS2,DEFB1,IFRD1,MAP1LC3B,PDLIM3,PRSS37,DLG3,RHOU,TMEM176B,CEBPE,RPL22,RRP7A,CCDC126,RBM3,RACGAP1,CORO1C,MAGEA4,STT3A,NPBWR1,RPSA,PIK3CG,ARHGAP15,RHOH,ERLIN2,HYAL2,UBE2S,SETD3,GPR75,TMEM126A,ACTL6A,ACP2,FOSL2,GNPAT,ZNF343,EGR1,DIO2,WBP11,ZNF436,STARD7,CHTOP,SYPL1,TIMM13,RPF2,XBP1,TBC1D1,GPR34,THG1L,PDLIM4,GABBR1,ERCC3,DIS3L,CA14,CEP57L1,TACR1,ARHGAP19,NACC2,CHRM5,DRD3,MTA3,EMILIN3,NAP1L3,CEACAM5,NAP1L5,SEMA7A,TRMT5,BCKDK,ZCRB1,MED4,APOC2,CYB5B,MRGPRX1,LIPT2,HPCAL1,ETFA,PRELID1,AQP3,ECD,CD59,SOX9,KCNG3,CHST10,GAB1,ITPRIPL2,AKT2,APEX1,PRSS1,PSMC5,TLR5,LCN1,RFC4,HS3ST3A1,TICAM1,GPM6A,PNPO,COTL1,CLRN2,SRD5A3,DCAF16,GTF3C4,MMP20,PLCXD3,C1QL2,REG1A,DNM2,ACTR1B,STAP1,HTR2A,SMARCB1,ALG5,SDHAF1,SUGP1,STARD5,FMO1,ABCC2,SCN2B,TEF,ANKRD10,PCP2,TCTA,ADD2,SOD2,MLN,KLF12,WDR12,IAH1,NEU1,AMELX,VSTM4,PDCD1LG2,RAB1A,GLO1,VSTM2L,FBXO31,MAP1B,CNOT8,PIGK,PELI1,TBCCD1,TRAF6,VPS72,KRIT1,ROCK2,KCND3,FUBP3,GIN1,TKTL1,RPL18,SPRY1,RPS10,CLDND1,CCDC106,ETNK2,IMPA2,TADA3,TRAM1,TMEM196,AP1M1,ECHDC1,FUNDC1,UBA52,MGMT,TRAPPC6A,MDC1,MTCH2,ITM2B,SP1,FKBP1B,LMO2,EDA2R,LCORL,PSEN1,MAGEC2,RASSF8,CLEC6A,KCTD17,SSBP4,RBP2,AQP11,TLCD1,SRFBP1,PFKFB2,ARHGAP12,EIF5B,MREG,ACER3,DIRAS2,YTHDF2,FAM161A,ANKRD6,PDE12,NAA16,GJC1,SLC12A2,RPS20,RUNX1,SCML1,ZFAND6,TAPT1,TYMS,MED10,ZNF581,SUCLG2,PDE7A,DUSP3,CIAO1,ATP8A1,KIF3C,GHRL,VPS18,GORASP2,THUMPD1,TTC9C,GMPS,PELO,IGF1,CCR7,SNAP25,RXRG,RRAGB,SNRPE,GRIK1,CMA1,DLGAP4,ANXA4,IL18BP,RASL12,GALNT2,RDH11,PIH1D1,KCTD3,HAUS2,ELFN2,GALC,RP9,LRRC8A,GNGT2,SSPN,CNPY1,LBX1,NKAP,MBD3,CDC23,DMPK,SYNGR3,TANK,BRAP,MPG,PRR13,SLC25A5,WSB1,LYZ,TOPORS,ZNF518B,CYBRD1,ADCK1,MACROD1,FAM151B,FAM136A,SLC35E4,TMEM165,KLHL25,RPE,SULT1B1,SLU7,VEZT,PTP4A2,FAM3C,MFAP3L,IRF7,KLRC2,TOX4,TMBIM1,CYTH4,CPNE2,IFT172,RAMP3,NUCKS1,IER3,CENPL,SGIP1,MRPS17,MECR,MRPL9,UBE2G2,FEM1B,FXN,UPRT,SUPT3H,CCDC3,VAV2,BTG2,ITGB8,TMEM229B,HINFP,CMC1,NUFIP2,GNB3,TRIM44,NR1I3,LRP10,TICAM2,FAM20B,FHL3,PPWD1,PQBP1,GPRASP2,CRYBA1,MPV17L2,THAP8,WDR45,NRM,HSPA5,GNA11,SERTAD2,HSPB6,HSPD1,EIF1AX,RNASEH2C,PNPLA4,TMEM115,NPC2,PARD6A,LRRC28,TCEA2,SAP18,EXOC3,TMEM81,CAP2,SLC22A6,SPG21,TIA1,DDR1,RBMS2,TGFB2,VPS54,SLC25A27,ATG9A,ZNF622,S100A11,THOC3,PIGA,GLOD4,BOLL,MX1,DPEP3,TMEM183A,BTG3,RUSC2,CD9,GRPR,IGFBP3,GADD45A,PYCR2,ZNF428,PDE2A,TNFSF8,CDIPT,SIN3A,CDK7,PLAC1,SCAND1,PSMD7,CTTNBP2,RAB6A,RGN,TNFSF15,SLC6A2,CD40,AIP,CRY1,ARFGEF1,MED22,NOG,TLR8,PMPCA,TRAF3IP3,PIWIL1,RGP1,CCDC90B,SRPK2,TAB2,LDB2,YPEL4,GADD45G,RPA2,TMEM107,DCTPP1,OR4A47,THAP1,CD34,FBXL4,CPXM1,PRCP,EID2B,SPINK9,SLC25A24,GLCE,SSNA1,GK5,STAR,RPL10,TRIP4,PDCL,SUPT5H,FBXW4,ST3GAL2,TAS2R7,CD209,PTGFR,IL2RB,IP6K1,ZDHHC16,TEX261,PPP1R11,MDFI,MSH6,RAP2A,APLNR,CYP4V2,SRI,NCAPG2,CNPY3,DTWD2,PSMD3,POLR1D,GPR160,RNF10,GP9,POLE3,LSM14A,CAPN2,SLC8A1,ICAM2,ABHD8,YWHAZ,STARD3NL,TM4SF18,TNR,BOK,GJA1,MAGED2,SURF2,SLC29A1,AASDHPPT,RNF222,REEP4,TM4SF20,CCNA2,HOMER3,CXCR3,MAGEB10,GRM1,PCGF6,SHPRH,KCNJ10,SLCO3A1,SPATA2,ADORA1,TAF1D,EHD4,CEND1,ZNF511,FAM81A,SLC25A1,HNRNPF,STAMBP,EPHA4,CTU1,KCNJ2,LIAS,TXNDC17,CITED1,ARL4D,CPLX3,TNNI3K,NPY1R,PSMD10,GCLC,DMTF1,PLG,DLK2,CDK12,PSMB7,TNFAIP6,FBXW7,ARL2BP,ING2,FRZB,SPP1,TSR2,CHRM3,PLCB1,GPR17,GPC1,PRSS23,ZNHIT6,COMMD9,STK3,CBLN1,HSPB2,TNKS2,LILRA2,LY6H,PLSCR1,PTP4A3,DCAF12L2,CREBZF,NT5DC1,MRPS18C,TRIM36,PROK1,JAK2,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,DDAH1,GPR35,HFE,NDUFA1,ALG11,TRIM29,CORO6,RB1,DPH5,PNMA3,RGL2,ITGB5,TRIM34,NDUFC2,TMEM205,NINJ1,ICOS,B4GALT4,CAV1,LXN,TCEAL8,YIPF3,RPS2,TTPAL,PMAIP1,CCIN,UBE2L3,EIF3G,MEPCE,SPEM1,CYP3A43,PDE4B,AKR1C1,MRPS11,CSNK1G3,RAB39B,CPLX2,PRND,ABHD10,HUWE1,SREK1IP1,CNTROB,FTSJ1,TBC1D25,AIPL1,PEX13,WDR11,NHEJ1,SLC35B3,FHOD3,TYROBP,SEC13,IL2,NBN,VMAC,TNFAIP8L1,ZDHHC4,WDR5B,CDC20,XRCC5,TIMP4,ACCS,SNRPG,MGAT4A,RBBP8,SGMS1,MRPS34,IGSF11,CYP2C9,DUSP21,TRIM45,ATAD1,PRL,MPPED2,CDC7,SLC19A3,NDST3,FBXO8,GGH,TNF,IL17F,PPAT,NUDT9,CYGB,TFB1M,LZTFL1,SNRPB2,KLF3,CCR4,CHRAC1,RPL26L1,PHF13,CGGBP1,KLHL1,FOXA3,SESTD1,CARTPT,ABHD12,BANF1,PARP2,NF2,DBR1,TAS2R13,COX6B2,TMEM170A,RNF133,PRKRA,TSPAN17,PRKCE,ZNF451,GNRH1,WDSUB1,LRRC40,CRISP1,ELK3,DPH3,CD81,MT1E,UBE2E2,FSTL1,RHOBTB3,HGS,POLDIP3,POLR2L,NUDT2,PEBP4,BAX,GH1,ATP1A3,PSD2,CRTC2,GSTM4,TMEM38B,TSPAN15,NPM3,PIK3AP1,PICALM,LST1,COX6C,XAF1,VTA1,RPIA,COCH,FEM1C,LY96,AP1S2,MAD2L1BP,TMEM47,AKR1B1,ADORA3,APEX2,TAB1,SF3B1,CPT1B,RBM27,ZBTB39,CNN3,ANKMY2,IVNS1ABP,PIK3CA,SNRNP40,FAM83B,JAKMIP2,CDH11,PSMC3,TMEM185A,NDUFS2,E4F1,TMED9,GSTCD,GTF2F1,DLST,SSX2IP,BCL6,TPPP3,ZNF263,SNX10,CA2,MTDH,USP6NL,SGTA,MIS12,GABRA1,CAND1,HSD17B10,PRNP,TMEM89,TRPC1,LYPD6,ELMO2,BCL9,ASPA,CBX3,DR1,GTPBP8,HS2ST1 |
| 4.662e-24 | -53.72 | ITFG1 (integrin alpha FG-GAP repeat containing 1) | protein interactions | 81533 | 538 | 260 | 19454 | 5460 |
FAM118B,RPL35A,EIF2B5,TNFSF18,SEC23A,RPL12,AIFM1,SRP14,HDAC6,CTNND1,RPS13,MDC1,FARSA,RPL23A,SLC25A10,NKRF,TCOF1,ILF2,APEH,HSPA13,LLPH,EEF1A1,TAF1D,RPL15,CCT5,TECR,CEP97,RPL22,COPE,RPL13A,PRKRA,GANAB,RTRAF,RPS20,RPS12,CTNNA1,TUBA1B,CTTN,CDC73,SDF2L1,ATP5F1A,RPL26,HMOX2,NDUFB10,CSK,SEC13,MEF2A,BRIX1,GTF2I,RPL4,MTDH,RARS1,HNRNPH3,RPLP0,MRPS34,GP9,HSP90B1,TMEM106A,RPS14,EEF1E1,AGK,RPLP1,RPLP2,RPL8,LILRB4,WDR6,RPL9,PHB1,HNRNPD,RPL23,HNRNPA1,EIF3D,ATG9A,PRPF19,STOML2,ICAM2,MRPS17,RPS27A,GTF3C3,RFC3,RBBP7,PRPSAP1,PCNA,RPS24,BAG2,HSPD1,SLC25A5,HNRNPA2B1,NDUFA4,STX12,RPS11,SART3,SNRPE,RPN1,RPL29,PPP2R1A,DCAKD,RPL19,B4GAT1,EIF4A2,TUBB,DYNLL1,RPL35,RBBP4,ACTB,SNRPD2,RPL37A,SNRPD1,RPS9,SEC61B,FAU,HSP90AA1,PFDN2,SP1,RPS5,LSM14B,RPS29,SCN3B,HADHA,ATP5MK,FKBP10,NDUFA5,SLC25A3,NUDT3,ETF1,WDR77,ACTL6A,AGTRAP,RPS16,SSBP1,EEF1B2,SYNCRIP,NDUFB4,RPL32,ALYREF,AKAP8L,TNFRSF14,RPS2,RPL10A,MAP4,TUBG1,RPL24,SNRNP70,CSNK2A1,GAPDH,ELOC,KARS1,COX5A,RPL17,TNFSF8,TMEM33,CD1B,HNRNPK,RPL3,MRPS18B,ABCE1,DHX9,LRRN4CL,MAP1B,SLC25A11,IL20RB,TFRC,SFTPC,RPSA,SEC61A1,MRPS28,CSNK2B,SF3B6,RPS3,IGF2BP1,CALU,EIF3G,ATP1B3,DNAJC10,RPS17,TIA1,SLC25A1,VAMP5,RPL7A,SUB1,MARS1,HSPA5,RPS15,HNRNPH2,RPL27,TMEM263,IDH2,NDUFAB1,UQCRH,HSP90AB1,CCT7,HNRNPL,RPS10,TCP1,LYAR,SNRPD3,SNRPA1,SUMO3,POLR2L,DDX1,NDUFV2,CTNNB1,RPL6,RPS4X,RPL28,PRPS1,TFG,HNRNPDL,COA1,HNRNPF,RUVBL1,RABGGTB,PICK1,RUVBL2,EWSR1,TRIM21,PDIA6,RTCB,RPL31,PABPC1,CCT8,LSM14A,ABCF1,RPS23,RPL18,TUBB4B,TMEM59,TUBA1A,EEF2,RPS7,TRMT1L,POLR2B,RPL10,ALG5,ATP5F1B,MATR3,DLST,RPS26,DNAJB6,CCT2,RBBP8,SPCS3,BTF3,RPL39,SNRPB,HNRNPAB,HNRNPC,MRPS7,NDUFS2,SRSF2,HNRNPA0,PHB2,HSPA8,DDX5,RPS28,XRCC5,TRMT112,SIGMAR1,MRPL12,RPL27A |
| 5.403e-24 | -53.58 | classic | COSMIC cancer mutations | classic | 14774 | 4432 | 16828 | 4835 |
CINP,FBXW11,PPFIA2,CNDP2,THBD,IL1A,BCL7C,CBLN2,NUDT12,RPL27A,TYW5,NDUFAB1,SNAP29,JAGN1,HTRA2,LGALS8,COX8A,TMEM147,USP8,PTK7,DHX38,GPR171,PGRMC1,NEUROD2,METTL15,IKZF5,RHOBTB1,CD247,FZD3,HNRNPA0,CHST2,CTSC,TMEM126B,NDUFS6,PCNA,DDX23,UBE2K,PDE1B,PIK3R2,CDAN1,SPRED2,PLD3,AGPAT5,CREG2,PCYOX1L,DKC1,ARPC3,FBXO44,DNTTIP1,LRRC3,HR,GNG10,MUL1,SMG9,NRN1,MAPRE1,ZFAND2A,MME,METAP2,SEC22C,NTRK2,GNG12,APOBEC3G,CNRIP1,USP15,ELMOD2,FKRP,LPAR2,ISX,GAMT,SIAE,GNAZ,RTN4,GLRX5,RNF144B,ARG2,DNAJB9,ADAM21,CLDN3,THAP7,UAP1,MGAT5B,PTAR1,UCN,CRLF3,PTEN,RLIM,DEPDC1B,INO80E,SNRNP48,ATG4C,FRRS1,SDHB,GFPT1,CENPW,RWDD3,TXNDC12,CXCL13,ABHD5,RORB,CKS2,EPHX1,RPA3,MOXD1,NEGR1,SIT1,FDFT1,KRAS,RPS16,RBM22,RRM1,TOM1L1,KDELR1,ZNF365,BAG3,ILF2,CRIP1,ZMYM3,PSMB1,NR2F6,HERC4,DKK1,ASNSD1,CNTN2,IER2,NDUFAF3,CHPF2,ILDR1,NLRP3,SCGB1D1,SHISAL2B,RASD1,CCS,SCG3,OLFM3,PPP1R1B,RND2,BMPR2,COMMD3,MRPL18,MFSD5,FGFBP1,G3BP1,CHAC2,POP5,PSORS1C2,METTL21A,DAPK3,DSTN,TPD52,RAPGEF5,DBT,ELOVL7,PCDHB13,RPS27A,SLC16A1,HINT2,TMEM101,NUF2,CHCHD4,CHIC2,FBXL19,LAPTM4A,MTA2,CCDC86,SUFU,MRGPRX3,KCNC1,PGGT1B,SLC38A7,SERPINA1,PMP22,STX11,LARP4B,LMAN1,NPSR1,PPP2R5E,SLC11A2,SH2D1A,UBB,ANKRD34B,HSPA13,DAAM1,LRRTM3,MRPL11,SCLT1,RAB27A,GRAP2,RELL2,TRIM15,PSMD4,NPPC,RPS7,DHX15,FBXL14,RHEB,BBS5,XCL1,TSPAN18,GANAB,RPS6KA4,PDHB,DDX46,MAT2B,MLC1,ZNF664,TCF19,SLC30A7,CCDC134,SLC6A6,GNPDA1,TMEM30A,AFAP1L2,COMMD6,KCNJ3,B3GALT1,UBL3,IMP3,NDUFB6,MRPL34,TMEM170B,TMEM117,NCDN,GNAO1,CST11,FASTKD5,SFXN2,SNX22,IL22,PRR3,SRSF7,STAT2,TAGLN3,SAV1,PCDH17,EPCAM,CBLL1,UBA3,GLRX,TOR3A,TOMM22,BFAR,TMEM179B,ST6GAL1,CSTF3,HENMT1,RPL7L1,CSGALNACT2,IFI6,AR,CCL2,GSTP1,LLPH,PPM1K,FAM43A,NLRP9,RNASE1,TMEM45A,LAMP2,PTPN4,RIT1,GPX7,CHRNB2,SSR2,ELOVL1,MORC2,SOSTDC1,EFNA3,SNRPB,TPM3,COPS5,STAT5A,LRRC3B,FPGT,FEZ1,PRDM4,EIF4A2,MAGEH1,APOBEC3F,MAP2K1,PLCB2,HSD17B6,RNF8,PEA15,EP300,ADAMTS10,TTL,MPDU1,VAMP8,TMEM70,PRMT6,PMM2,PPP3R2,PRSS12,TIMP3,CHST13,ZNRF1,AQP2,SMAD1,CLEC18A,PPP2CB,FKBP8,KLHL24,GABPA,RCL1,IL2RA,PPAN,SEMA4C,RABGGTB,FBXO7,SLC2A3,CLLU1,RPL23,SPIN3,HP,STOM,CTTN,CDNF,TNFRSF1B,TGFBR2,CAPN1,USP3,ASZ1,METTL22,CYP2C8,FLOT1,NR2E1,DROSHA,STARD4,THOC2,DCTD,FAM177A1,MCM4,SCNM1,SOX14,PDAP1,CHMP4C,IGF1R,CX3CR1,SLCO2B1,MAVS,UBP1,KLHL22,UMPS,RAB19,CD1C,MRPL22,SS18,CDCA7L,SIAH2,CHCHD6,CER1,POLR1B,RFXAP,EPS8,HOXC4,UPK1A,BIRC2,MTM1,IFIH1,NUDT7,FCGR2B,SCML2,VGLL4,DNAJC19,ELF5,PKP4,GPR176,CLDN12,CCNY,CHKB,CRHBP,CNOT2,PLEKHO1,MYBL2,ZNF326,ERAS,GSTM5,GLRX2,APOBEC3H,LANCL2,PRKACB,ASB7,KLF1,VDAC1,CLPB,FEN1,CBR3,CLEC2B,ADD1,UBIAD1,LRRC61,GTDC1,POLR2B,TSNAX,DHRS13,PARL,SLC7A8,RFC3,REG1B,GPM6B,FBXO22,EGFL7,TMEM59L,SERPINC1,ACP5,HLF,ATP6V1A,COPS7B,DENND2D,KLF4,RNF34,ACBD6,FAM53B,PRDX1,TAF10,ATG7,PREB,TUSC1,NPW,NFKBIA,ETF1,LRRC8B,TRIM68,TMED5,HARBI1,USP16,LTB,PFDN2,TCEAL1,AK3,CLCN6,SLC25A12,HMGCS1,DDRGK1,PSMA1,RPL32,SHOC2,HDHD3,REN,CCR1,DTWD1,SMPD2,SOD1,NCBP2,ASTN1,ATXN10,TBC1D13,IQCK,TP53INP1,DECR2,AVL9,VEGFA,FAF1,CRAT,TM4SF19,SOBP,PTPN11,NOTCH2,NAPA,TMOD2,GNPDA2,IFNB1,CSH1,BTN2A2,UBL5,POLA2,UBASH3B,MNS1,POLB,KIAA0513,CCNH,SEMG2,SPSB3,TOR1B,FAM83C,ABCG2,MRPS9,LTA,PTH2,MTF1,PRICKLE2,RPL27,PPP1R1A,MSTN,CLDN9,SYNCRIP,SLC35F2,TRMT112,DIO1,VGLL2,SLC16A10,ZNF821,GTF2H5,RPRD1A,HINT3,VRTN,SLC25A10,DDX50,PPP2R2C,BST2,STK4,TNKS,SLC22A17,PLS3,CYP1A1,ST8SIA5,ACVR1C,FAM181B,NKIRAS2,IL1R2,TMEM41A,KLF9,STUB1,PIP4K2C,TRAK2,SRSF2,UBLCP1,GSTA1,SERPINB1,ST7,AVPR1B,SNRK,TEX264,AGTRAP,KCNAB1,PPP1R3C,CRADD,APBB3,MCMBP,SEMA5A,S1PR4,TMEM11,FAM169A,TNFAIP1,LAMP3,CNOT6,REEP6,CHPF,MATR3,SELL,KIAA1143,ZNF473,GNL1,GNB1L,DNAJC2,ATP1B3,PPY,CRYAB,ROMO1,SYNGR2,RNF11,CYTH2,TAF7,APOC4,TLR10,WDR82,FXYD6,NAB2,CD28,ZBTB25,PNMA5,MANBAL,CD86,ENO2,PSENEN,SLC2A8,ZNF704,FARSA,UBE2H,KBTBD6,PTPMT1,CYP2R1,FGF23,SLCO1B3,GOSR2,G6PC3,RANBP6,PRR5L,CD14,SLC25A39,CCL27,ZC3H11A,ELF1,WSCD1,SFRP1,TMX2,HTR1A,RPS26,RNF40,DAP,KDELR2,DDX1,TP53I3,RNASE6,DPM2,IRGQ,BRIX1,CFL1,KLHL3,PNMA1,VAPB,CALML5,HEBP2,SP2,CASC3,SLC6A3,TCF21,CNKSR3,SEC23A,TIRAP,MYL6,RPS9,GEMIN8,TUSC2,GPR173,PSMG3,TOP2B,KCTD10,MAB21L1,RAB35,SHISA2,PPP1R8,MKLN1,CCL28,EEF1E1,CMTM6,VPS26A,MYC,LILRB4,SMG8,TMEM50A,FEM1A,SEC11A,CD40LG,PIWIL3,IL2RG,SNX1,FTH1,CCM2,ALB,SLC35F1,PSEN2,SYK,SLC25A26,CLN8,ACO2,VPS16,SLC48A1,CDC42,TNFAIP8L3,SLC38A1,BACE1,DUSP10,PCBD1,TTC23,CACNB3,AGR2,MORF4L1,TMEM174,NLGN1,LCN8,CPSF4,CD63,AGA,DNAJC24,CLEC1A,AKAP1,PCSK9,PSMA6,KBTBD3,CLIC4,NPTX1,COX11,HNRNPH2,HMOX2,ADM2,AHCYL1,ALDH1A3,IZUMO4,TMEM108,FAR2,SURF6,BRD3,TESK1,DVL2,RPL39,C2CD4C,TTC33,MMD,WRAP53,BET1L,KLHL26,TRAPPC4,EEF1A1,UCHL3,GAS2,TFPI,PRKCA,RPL9,RNF5,DGCR8,TST,API5,TPH2,CRYM,SAMHD1,KCNS1,SPRYD4,DNAJC30,SRXN1,FKBP1A,DOLK,NT5C2,ZMAT2,ST3GAL4,MRPS18B,EHD3,KCNJ8,SAMM50,ENC1,TRIM6,PYGB,SLC4A10,FOXP1,PDE8A,PSMB9,HOMER1,RCCD1,EXTL2,SLC20A1,ALPL,LAP3,ADIPOR2,EFHD1,C2CD2,ABCB9,ATF1,FAS,COX6A2,POLR3GL,MAD2L2,UBTD1,TMPO,RBBP4,ARMCX3,COX16,CUL3,MAN1A2,POLD4,AKT3,ERVFRD-1,CCDC92,EIF3D,DNAJC4,RBP5,CHMP2B,ELOVL4,GRB10,SKA1,BHLHE40,MAP1S,PI16,HDAC3,NLRP2,MRPL53,GLRA2,RPL29,ANAPC4,ARPP19,GDPD3,GREM1,TOMM40,LRRC4B,MPHOSPH6,FABP4,COX4I1,SDC2,FAH,ACVR1B,RPL10A,CTDSP2,RAD21,RAP1B,C2CD2L,TXNRD2,DNAJB4,LAT2,FITM1,ACTR1A,POLR2G,COQ10B,SNX14,AIFM1,CARHSP1,TIMM8A,NPC1L1,KLHL9,APPBP2,CLEC7A,GPR146,KCTD11,ARPC2,GINS3,MYL12B,IL7,ZHX3,PID1,SH3BGRL,EXOSC3,NECAP2,SRSF4,SNX33,TMEM42,NDP,SDCBP,USP13,MED23,DRG1,FGF3,SRPRB,CEP85,ERLEC1,POLR2D,SNX12,KRT222,CNTFR,NEURL2,SMNDC1,PDP2,LGALS3,NMBR,LUC7L3,HHIP,MAP4,SMYD3,DDIT4,RAB3A,CTNND1,LCN12,FAM91A1,YIF1A,CA8,EGR2,LRRC20,HAX1,RPS3,TMEM60,CHN2,AIF1,CALU,HBEGF,FOXJ3,UFM1,USP30,RAD23B,CD83,DNAJC7,UQCRQ,KCTD12,RPL12,GFOD2,ADAMTS20,SOD3,DUSP22,MTMR2,ICAM1,PLCL1,GABRB3,FAM187B,MRPL49,YWHAH,LSM2,CCT8,TMBIM6,SH2D5,HMGA1,UTP6,FOXI3,IPCEF1,TSPAN11,GGPS1,MND1,AUH,IDE,ZNF267,TTC8,TFRC,HSD17B11,ZNF652,ZNF177,C1QTNF1,FBXO11,SPSB1,RBBP9,WNT10B,DGCR6L,ETFB,VIP,LRRC8D,NTNG2,TFDP2,C1D,ZNF22,ACTR3B,MIF,EEF1B2,ZNF189,RBM15B,HRH2,APTX,AP2A1,ZNF688,SPINT2,TMEM45B,BCL2A1,GADD45B,MGST2,SENP8,STX7,NECAP1,GPC4,LIMS2,MZT2B,HBA1,TRIM35,TRAFD1,PKIA,PPM1B,TP53,INMT,CRELD1,NFKBIL1,TAX1BP1,AP2M1,PRDX6,KIN,SLC25A46,HSD17B1,TMED4,HEXIM2,TBC1D17,KPNA6,RWDD4,IRF8,TOX,PTRHD1,FCER1G,CYB561,BET1,SYNDIG1,GSTM3,TSEN34,FTSJ3,MTHFS,DUSP6,SETD7,PPIF,DAG1,ZBED3,CYB5D2,RPS12,TXN,MAF1,GABPB1,ARF4,SCGB1C1,RDH12,ZNF790,TAX1BP3,TNFSF12,CALY,PML,GABARAPL2,PSMA4,DNASE1L1,SERTAD3,EIF1B,MT3,ENO1,GNPTG,CRYL1,CHST7,SERPIND1,RPL24,TFPT,ELOVL6,ALOX5AP,SLC25A14,PRDX4,MECP2,ZNHIT1,TBC1D19,CLSTN3,RASL11A,CSTA,RGS6,RPRD1B,DCAF4L2,LYPLA2,TSPO,SNRPN,STYK1,POP7,RNF181,CELA3B,GPD2,CYP11B2,LBR,FBXL7,PHF21A,CAMP,TRMT61A,RHBDL3,SLC1A2,THNSL1,COX5A,CAPG,TLR1,SAR1B,RHAG,IL12A,BRMS1L,DHRS1,FBXO34,HCST,ZBTB16,ANAPC16,CHORDC1,NAA15,SERPINB6,SYBU,EXOC5,FTHL17,RALA,WDR55,G6PD,ADK,F11R,PPP2R5A,GAPT,TLR7,VASH1,ACADS,PTGES,RNF128,TRAF7,MMACHC,DUOXA2,MTMR12,ABHD16B,RAP2B,TNFAIP3,TAPBPL,RRAGA,ETV6,SIRT7,IQSEC1,NOL4,FYTTD1,ALDH1L1,MAK16,TSSC4,NONO,POLL,SPRED1,H19,SIVA1,GFOD1,NDUFAF2,GPR37L1,SNAPC1,SNTA1,SV2B,HPCA,SOST,TCP11L1,EIF4EBP2,OR2A2,NAB1,ENPEP,LSM6,RTP4,ZMAT5,SYNGR1,PROX1,FGF13,PRKX,ZNF174,USP38,CERK,USP39,SLPI,ADCY3,SNRPD2,ESR2,DCAF5,CDK6,CWF19L1,CTNNB1,RAB8B,INTS12,SOCS2,CYP2D6,SFTPD,CLEC12B,FAM200A,S100A10,NFYA,TOLLIP,BATF,TGFB1I1,DUSP1,STX8,MTAP,RAB3C,PWP2,URM1,CETN3,CACYBP,CTSK,AP1G2,NDNF,ANP32B,CPT2,CHST9,TMED3,ACOT13,WFDC13,CCND1,RPGRIP1L,OR2W1,COX7A1,FBXO9,LCN6,SETD4,BMPR1A,FAF2,ARHGAP21,SCG2,SPINK13,RHCG,MPHOSPH10,MRPL47,S100PBP,TMEM33,AP3S2,KLF10,KIF2A,MIA2,BACH1,INPPL1,DEGS1,CRYBA2,CYC1,POU1F1,NPTN,FCAR,CCDC42,ARMC8,ENTPD4,SLC35A2,ID1,PTDSS1,CDKN3,BPGM,PPIB,CD164,SPEF1,SCAMP2,DEK,NLGN2,CYP4F8,PRKD3,SLC5A6,PGAP2,CTSD,FABP5,MRGPRX4,NFE2L1,NOP58,SPATS2L,AKR1A1,MRPS25,RBCK1,GSK3A,PRCC,UBXN10,NUBP2,LDHA,PFDN6,SLC20A2,PCDHA5,ATP2C1,FATE1,DNAL4,RC3H2,RANGRF,NUDT19,THOC1,ABCC5,INTS10,SURF4,XPO5,RNF103,CREB3,TF,EFHC1,SLC25A32,GJA10,EEF2,THRAP3,EXOC2,XPO1,ZMYND11,ZNF513,SLC7A4,RNF187,APOBEC3C,GPR162,CXXC5,CIRBP,ENDOD1,SH3GLB2,EIF2B5,GALE,FUT8,GTF2A1,WBP2,NEK7,UTS2R,SPOCK1,PHKG1,LASP1,GLE1,AQP4,TXNIP,CREBL2,GNMT,CCL25,PSMD6,IL23A,SLC39A9,FURIN,DHX9,ZSCAN1,WDR37,EIF4EBP3,WNT7A,STX17,LEPR,APH1A,NDUFB8,ISYNA1,NAA11,EIF1AD,XPOT,FRA10AC1,PDIA3,SNAI3,CDC37L1,PELI3,NLE1,KRR1,MSX2,RPRML,SERPINH1,RPL37A,ZKSCAN1,CLDN14,HSPE1,PGBD2,STAMBPL1,SIPA1L1,GXYLT1,NUDT16,LHFPL1,HSPB1,KCNA2,B4GALT6,LEAP2,HADHA,TRA2B,RAB4A,SOX21,DHX16,SPATA2L,TBCE,NQO1,IPP,TAC1,LMBR1L,NPVF,IGFBP4,AKR1C2,CDKL2,CHRNA7,KIF1C,GAS8,BRMS1,CD3G,TMED1,RBM23,BRI3,HEXA,ADAT1,KCND2,NDUFA5,CCL21,PTCRA,TRMT6,HBB,FGF17,NEDD8,CXCR1,WWP2,RABAC1,RAP1A,ACAA2,UCKL1,POLR2I,CD2,FBXO30,TIGD7,LPXN,RASGRP2,ST13,IL34,DFFA,MFSD6L,LYG2,AAMP,ZCCHC10,SYN3,GPBP1L1,MX2,MTPN,WDR77,MEST,FZD4,ATP6V1G1,SERPINB10,TSEN54,FBXO42,TMEM215,ZNF24,MLF1,GTF2E2,TBC1D10C,CCL19,MAGOH,NKX3-2,JAK1,LBH,AZGP1,HBE1,ABCB1,INO80C,FGF1,AZIN1,PSME2,SMAP2,RAB3B,CDCA3,KTI12,NDST1,DHRS3,DEFB116,TNFAIP8L2,CTNNBIP1,GNG7,ATF4,GSTO2,KBTBD2,RARRES2,PIWIL4,CSNK2A1,KPNA1,KIT,RS1,AFTPH,LSM3,SUPT7L,JOSD1,MMP9,BTF3,CYP27A1,DYNC1I2,S100A6,LHX2,CDC73,UBAP1,ZYX,DNAJC5,TMIGD1,ALKBH4,SLC7A9,HEBP1,MYH2,SNAP91,ROPN1B,VRK1,PGK1,SCFD1,TTC4,CCDC47,RPL15,TUBG1,CACNB4,GHITM,PRMT2,CIB3,TACR3,SRP54,BUD31,TMX4,CAMK2G,FAM89B,RCVRN,PEX3,CCDC127,CD200R1,KCNJ11,PPP3CA,CRYGB,FGFR1,HCRT,CAMK2N1,PYGM,SHC1,ANAPC2,FBXO32,AGK,PSMB5,MCOLN1,ENPP4,CCT5,SBK2,SORD,AGER,CD58,IMPACT,RAB18,FKBP14,IDH2,ARMCX5,ZNF593,PRPF4,RMND5B,PGS1,SLC25A21,RBBP7,TRIM37,HECW1,ZBTB38,NFIL3,HNRNPC,SETD5,PTPN1,SPR,PPARG,GALNT12,ARFIP1,TRIM21,SIX5,ACTA2,ARMCX2,HEY2,RBM17,PCDHB8,PKNOX1,ADRB1,ZDHHC14,RFX4,FRMD8,RNASET2,SPTAN1,SLC35E3,LRP12,NPY2R,CLDN11,NIPA2,RABL2B,FAM199X,TRAPPC1,MDM2,MGP,EHBP1,MRPL13,TMEM156,GSTO1,CCDC69,PSMA3,AK2,SOCS5,GALNT1,CNP,RND3,B9D1,NUDT3,LYAR,UST,EXOC8,PFDN5,TOM1L2,GNRHR2,RAB11A,PPIL4,CCNI,CDO1,DPP10,PRRC2A,CRABP2,IL20RB,DKK3,SF3B4,COMTD1,FNDC8,AKT1,DLX1,FGD2,APEH,FIBIN,WDR38,SNX20,L1CAM,TLR9,POLR3H,TMUB1,C1QC,TRIM3,EDF1,TMEM219,ATP6V0B,ZNF207,MEAF6,UGCG,LIG3,RPS14,LYPLA1,SLC25A31,ZNF671,SLC17A5,PRIM2,SNRNP27,CD99L2,SDR42E1,PDIA6,UBR7,TRIM32,RNF141,KLHDC8B,KLK9,PLA2G5,ARHGAP1,DOK4,GDI2,MRPL23,GFM2,E2F6,GPR89A,EFCAB7,EXOSC1,ZMPSTE24,ING1,STRBP,IRF1,NHP2,TRIM23,NAIF1,ARMCX1,UBE2A,UBE2D3,ATP6V0E1,CCT2,GABARAP,FGFR1OP2,GRPEL1,TCP11L2,ELMO1,PRPSAP1,LTBR,CASK,GAL3ST1,CLU,ATPAF2,KIAA0232,LMO4,CNIH4,GLUL,NCKAP1,NRP1,CDK5R1,ZNF397,APOBEC3A,SEC14L1,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RC14,PRDX3,PDCD5,EMILIN1,BTBD10,ZMYM6,EIF2B2,ARF1,GNG11,HMGB1,MRPS26,PHF7,CKB,TUBA1B,THAP6,HNMT,ERRFI1,FA2H,KCNIP2,SERTAD1,ZHX1,GPR83,LPCAT3,PPIL3,ZCCHC7,PHTF2,CTSA,DPAGT1,UBE3A,PDE6D,PDZK1IP1,OR5K1,LRFN3,S100B,TNIK,RIT2,CACNG3,CETN2,TADA1,ZC4H2,EFNA5,ASPM,ZC3H14,CBFB,LEP,SH3BP4,SMARCE1,PITHD1,LSM12,FIG4,RPL7A,CXXC1,MAP2K3,SEC22A,DCTN4,DOK5,ZDHHC24,ARF6,PPT1,B3GALT2,FGR,MRPL12,SPHK2,RCHY1,EZH1,ARGLU1,MRPL16,TECR,RNF7,MAP3K3,FHIT,ARL11,MED29,TMEM106B,UCP2,UBE2I,MFAP1,MXD1,SLC41A1,LAMTOR2,PNRC1,PLEKHF2,SERINC1,SNRNP70,GLIPR2,MID1IP1,TDP1,SPCS1,RPL19,IL21,SAP30,RNASE4,DDIT4L,SLITRK5,ZNF362,POU5F1,FGF16,HBM,MSN,MAGEB1,SLC6A7,DICER1,LGI1,CDC5L,TMEM19,SLC35A5,HPS6,CH25H,CRMP1,KCNH8,TCP1,CNOT7,RABIF,ADRM1,CD80,TAF11,IREB2,HNRNPL,UBTD2,EMX1,PKIB,SMAD2,PITPNB,GNAQ,POLR2C,LPAR6,CCDC167,NFE2L2,RAD1,DBNDD1,GIPC3,NGRN,NCOA5,IGF2BP1,GOSR1,RUVBL2,PPIC,MMAA,NDN,SIKE1,CHCHD1,ARMC6,TBC1D5,DBH,CLRN1,SNX3,VDR,CTTNBP2NL,IL5,PTGDS,TNNI1,ADRA1A,PEBP1,PSMB2,FGF22,CX3CL1,COL3A1,CBX7,VAMP1,ADRB2,GPT,SRSF12,QSER1,MYO1B,SLC2A1,TLR4,SLC6A1,GPN2,NKX6-2,SLC38A2,PLAC9,HS3ST5,GPR22,SSR3,LIN7C,PFDN1,TAF2,NCSTN,ANXA7,SGMS2,ANO3,UBE2N,PRR19,CCL1,CTRB2,NGDN,FKBP4,STX16,PSKH1,PMP2,DPPA2,SMURF1,EIF5A2,PI3,PPP1CC,OR4E2,PEX26,BAZ1B,ZNF32,NOP16,TNFRSF9,KCNB1,LRRC8C,DMAP1,PLEKHO2,SCAMP5,CST3,LYZL4,YWHAG,BCL2L1,ICA1,DCTN6,VDAC2,ACVR1,IFT57,MYH1,B2M,TIFA,TPRA1,SASH3,SLC15A2,CASP4,CYB5R4,TRIM22,DEFB129,SPOP,NR0B1,AMACR,FITM2,ITM2A,DCK,ADH1A,EAF2,DCUN1D1,NUDT4,MCM6,RPS24,CYP7A1,SDS,PRRT1,GINS4,ABCE1,DIRAS1,ACTN4,PTGES3,RGS10,GATAD1,RPS15,ASB1,FBXL3,VIPR1,QRSL1,HSP90B1,TCOF1,LRAT,MCPH1,NKRF,RETN,ISOC1,EDDM3B,ZDHHC8,TPPP2,EDEM3,KLHL28,EGLN2,MRPL33,UQCRC2,RNF152,CXCL9,MRPL17,RBPJ,CFDP1,DUSP9,ATP2B4,SIGMAR1,IFNK,GAPDH,CRYGA,CBLN3,VAC14,SLC25A42,CLIP3,YES1,GRIA1,HECTD3,PI15,HDAC5,FGL2,UBL4A,GKAP1,ASRGL1,MADCAM1,MFSD6,POU3F4,PSMC4,MPST,IDH3A,JRKL,RFC5,MED13L,NSDHL,TMEM97,SLC35C1,ANKRD50,RLN3,NEO1,ESAM,PCCB,HSD17B3,PDIA2,SAP30L,RNF146,SNAP23,FAM76B,ELOF1,GGCX,CCAR1,TSSK1B,NTRK3,PICK1,AGAP2,GUK1,STX1A,FBXO3,IRF2BP1,ACHE,CSE1L,UBE2B,STAC3,FAM3A,MNAT1,NEK9,CDK5RAP3,TNFSF10,FMO3,CLDN6,CAPZA1,SRSF1,ITGA2,COX6B1,SLC31A1,LMBRD1,UCK2,MAPRE2,FGF7,EPHA2,CAV3,PRPF18,CDK2AP2,IGSF21,IFT52,PIK3R1,FADS2,F7,ACOX1,TSPAN7,KDM2A,POLD2,KLHDC8A,EXOSC8,ZNF574,SUMO1,DCLRE1C,G3BP2,OR2J3,LHB,DEFB124,INSIG2,CBL,HSDL1,KLHL23,WDR6,IL12B,ACOT6,ANGPT1,NCALD,KCNK17,ZGLP1,COPS4,RAB28,COX17,DDI1,MDH1,CYP1B1,FAM168B,ELK1,RALYL,MRAS,MRPS35,ATP6V1G2,MMP14,RAB6B,CD38,MT1A,ANKRD49,PNMA2,RMI1,DLAT,CUTA,CAMK2N2,RIMS3,GRM8,EIF4E2,IL13,MCM8,UTP15,HP1BP3,TLCD2,TAS2R16,GEMIN7,ZBTB33,PHF12,BAG2,MED17,DCP2,TMEM184C,NOB1,GRAP,EPYC,TAAR6,PHC1,BLOC1S3,UGT2A3,PLXNC1,TMEM74,TIMM8B,IRAK1BP1,CYP3A5,CD52,LMNA,PHF1,DCUN1D3,XPNPEP1,PLP1,DCAKD,ZNF7,RNF41,MGAT4B,DNLZ,BUB3,EXOSC4,CFL2,SLMAP,SNX5,ZMYM2,KLRD1,FASLG,MSRB3,CDC42EP4,CTBP1,EIF3E,EXT1,ALKBH3,JUP,BEND6,PRMT5,TRA2A,SATB1,ACO1,GANC,RALGAPA2,PPTC7,PCK2,UBAC2,SFXN1,UBXN6,KCNF1,CD4,NME2,NR4A2,SLC25A45,NOSIP,LIMD2,TRIM27,COPS2,LGI3,C1GALT1C1,EIF2AK2,GTPBP2,SLC25A20,TSHR,EIF2D,INSM2,AIG1,NEUROD6,STC1,DRP2,DYRK1A,SRGN,KLHL32,NOVA1,INPP5K,NUDCD3,SEC63,MCAT,IRF2,TM4SF1,ERP29,PTTG1,BCCIP,CAMK1,WFDC5,NOL7,SNX2,NSA2,TACO1,SSBP3,DEFB115,REXO2,DTD1,NTF4,POC1B,GPHA2,CYB5R1,LRTM2,MYT1L,USP2,CYP4F12,SLC39A13,CPE,PCSK2,ARHGEF6,DCAF4,SCN1B,CDC40,NELL2,SUB1,NDUFB5,TM2D2,CLVS2,WDR83,VAMP3,VLDLR,DHRS7,CRB3,ELOVL3,TFG,CYB5A,MAEL,MTX2,BSCL2,RNASEK,CDK8,COX10,PHF23,SYT4,WDR20,HRAS,TAGLN2,RPP14,RPL13A,TRIM8,FAHD1,HELLS,IKBKB,LCA5L,MITF,HTRA1,SPCS3,KIF3B,CLCA1,TMEM88,MRPL40,TRMT11,GTF2IRD1,CD1E,ZSCAN5A,B4GALT7,TFIP11,GABRG2,WASF3,PRKCQ,RPL8,CLEC9A,IKZF2,HADH,NAT9,PGM1,TRIM52,HNRNPA1,ACOT8,SLC16A4,POGK,LECT2,NFE2,LRTOMT,RPS29,SKA3,ALKBH2,CTSB,DEFB121,NCKIPSD,COX19,RPS4X,SOX3,TMOD3,MAP3K12,ZDHHC15,RSPH1,PPIA,FBP2,CUL2,PYCARD,SLC6A8,CXCL11,MED30,GHR,TREML1,MED9,SOCS4,ASB8,INPP5E,CDC16,GLTP,GNB1,SEPHS1,LACRT,ANAPC11,TOMM7,RASGEF1C,PCMTD1,CA10,MAD2L1,MAP2K6,RHBDD3,GSTA4,RBM42,PPP5C,FOXP3,LDLR,TMEM160,VPS4B,STBD1,FAM110B,TIAM1,IL4,THAP2,TRIM63,TRIM46,DNAJC1,HCLS1,GLRB,EHHADH,EMP2,LILRB1,CHID1,DISC1,RBFOX3,NETO2,SMARCD3,AVPI1,SSR1,SFN,MCHR1,ZNF596,PSPC1,GNAI3,SF3A1,TRAPPC10,FAM50B,STX10,TUBB,COIL,ZFP64,SCPEP1,NSFL1C,TMEM190,POLR2F,POMT2,NDUFB10,PLSCR4,LRRC57,MOG,NMI,SCN3B,NDUFA2,RIMS4,IFNGR1,BTF3L4,HMG20A,ARL6IP6,TLE1,PNOC,CYP27B1,MRPL10,IL15,NTPCR,YBEY,TMEM14B,GNG5,NIF3L1,UTS2,DHPS,RRN3,TNFSF13,FLRT3,GRPEL2,STIM1,FTL,LRIF1,TMC7,PPM1D,IDO1,SERPINI1,KLHL12,CXCL12,MSL2,FLCN,SLC39A3,SLC25A28,RPL35A,RSRC1,CD248,ZNF668,MRPS7,CCL20,ZNF575,ARHGAP5,VTI1B,SPATA6,FAM162B,GLT8D2,EIF4E3,MYOZ3,TCAP,DES,ARHGAP25,RIC3,LIN7B,ZRANB2,PCDH9,CCT7,CKLF,PSMD12,KCTD15,SLC25A11,MS4A7,HNRNPD,RAB33B,SECISBP2L,IFIT2,RNF115,CDC42EP3,MCM3,MGAT1,RCE1,ENTPD3,RASGRP3,RGS19,YTHDF1,RPL7,TUBA1A,FCGR2A,NAA50,CELF6,SH3BP5L,MED31,CCDC85B,SEMA6C,LUM,NEUROG2,MTMR6,UNC50,ICAM3,HMX2,CHST11,METTL6,RASL10A,IDH1,IFNA2,GNG13,TUFM,MPZ,VPS28,CD2AP,SRC,LANCL1,PIK3R3,MORC4,CISD1,SLC35B4,MKKS,TERT,PTGER4,TRAF3IP2,TOMM20,DHRS7B,BAHD1,PEG10,IZUMO1,PSMB6,ZCCHC17,PIP5K1A,CHRDL1,NLRP6,LNX2,SNX18,TYW3,RFC2,GNB4,CPNE1,ZER1,CNTN1,ACTB,DDAH2,MATN4,UGDH,RNF121,AP2S1,PGAM1,RPS13,EPO,NFKBIB,CHCHD3,EID1,MMP21,ZNF280B,HDDC2,CD1A,HSP90AA1,LPAR1,DCUN1D5,PPIH,FNDC9,PDRG1,FOLR2,PTPN22,SOCS3,UBFD1,GSTM2,NAA35,PPIG,NRBF2,PPP4C,EFHD2,GGT7,GRXCR1,DNAJB2,PSMA2,NICN1,RSAD2,RAB30,GABRA2,PFDN4,SST,COMMD5,CNR1,CAMLG,PLA2G12A,NPY,ZBTB2,MFN1,DAD1,TAS1R2,PSMC1,TWSG1,SSRP1,TTC32,MED21,RLN2,NDUFS3,HPGDS,DNTT,GOLGA5,MORN4,GIMAP4,RPAIN,TBC1D4,UNC119B,GABRB2,ARMC1,CES5A,SYVN1,HSCB,TFEB,GRID1,IL6,CCDC122,PPP1R12A,RERE,FGF10,TLR2,DYNC1I1,HECTD1,LGR4,CNPY4,SMARCA5,DRAM1,VKORC1L1,IL1RAP,ATP1B1,BAK1,FAIM,ELK4,PPP2R3A,GPR85,RILPL2,FZR1,SLC1A3,SLC22A8,SMAD4,DRD1,LRRC1,TM9SF4,TCEANC2,ITGAV,GPBAR1,FERD3L,USP5,MXI1,RNF126,TMEM182,FOXP4,RPF1,LDHB,AURKAIP1,AKR7A2,AGAP1,PIR,UBE2M,UBE2E3,SLC6A12,TRIM10,ELAVL2,MOSPD1,ISCU,FCHSD2,TNNC2,GTF2E1,SMC4,RAB22A,AK5,FAU,CLVS1,PNO1,KBTBD4,PSME1,CYP2F1,SYS1,GPR26,IL1B,BAP1,PLAA,FUT1,DOHH,DRAP1,MEF2C,LRRC4,LITAF,ARL4A,ARFGAP3,ZNF175,LAMTOR3,SNRPD3,TP53INP2,GPSM3,TESK2,COMT,STK11,TNNT2,GOLPH3L,ELAVL4,SEC61A2,RPS27L,ANGPTL2,RHCE,LY6G6C,FKBP10,PHAX,BAALC,FGF12,SEC62,GPX4,EXOC1,RIMKLA,CCDC71,PDE9A,SLC1A1,CYTH1,SNAPC2,SLC22A12,RPS5,CCHCR1,UBE2F,CYP17A1,FOXP2,TPSG1,UBN1,RAP2C,ADNP,LAMTOR1,EIF4A3,DDX5,CSTB,DET1,ZNF330,MCHR2,KLHL7,GTF3C3,RNF14,GPNMB,SAT2,PRRG1,RGMA,DNAJC10,IRF6,RAF1,MBLAC2,ALG2,PHKA1,SCYL2,RPL10L,COG1,KDSR,DNAJC27,LRRN1,GCC1,CD1B,DNAJB6,ZFAND2B,STARD13,B4GALT1,PSMA5,AOX1,ATP1A1,CRKL,TGIF2LX,CNPPD1,NLRP1,FBP1,TMEM199,GZMK,STX12,CENPP,RP2,KATNAL1,TMOD1,TXNRD1,TNFRSF14,RPS11,KCNMB2,GTPBP1,NAE1,GSTK1,DNAJC25,NUDT5,NDUFA12,ARL15,ILVBL,EGFL8,AZI2,PEX5L,MAGOHB,TM9SF1,COMMD2,FAM118B,ARL10,MYCT1,CBX5,KCNMB1,TRMT1L,CD46,GABARAPL1,GNAI2,CDC123,UCK1,RPL3,MTG1,TOPBP1,QPCTL,RBM18,GLRA1,G2E3,VMO1,C1QL3,MRPS18A,TRIM11,CSNK2B,YIPF4,HOXB1,NRSN1,RHOB,TMUB2,MAX,CDC42EP2,PPM1G,DEDD,BOLA3,FLRT2,GLYAT,GFI1,TMEM209,E2F4,CD1D,FCF1,MYD88,MRPL52,TXNL4A,TSC22D3,USP14,NANP,GNA14,CXCR6,CISH,BTG1,EIF2S2,ZMYM4,AGPAT1,ASB3,CHMP5,PBLD,HDAC6,RNF39,CNTNAP1,ANAPC13,TMEM176A,DUSP26,EYA3,GTF2A2,ACTL9,PPARA,COPS7A,GPR15,RNF20,TOR1AIP2,MICB,STOML2,RERG,FRS3,RPL35,POLR3F,RRAS2,SNCB,TPT1,ATL1,STXBP6,KCNQ5,TPBG,LILRA1,PDE1A,DAPK1,NFYB,SLC25A17,LRWD1,ZCCHC12,ARRDC3,SESN3,CDSN,SLC25A44,ZNF692,YWHAB,TESC,THY1,EDNRA,TBC1D24,ST6GALNAC3,LEPROTL1,TMEM95,SYT2,SPOPL,MMADHC,TTC1,PHB2,PRPF31,NR1H2,BMP1,PKIG,MOBP,ADCY2,TSG101,MAMDC2,DRG2,CALR,TRUB1,SNAI2,THBS3,SHMT1,SYNGR4,PPFIBP1,HEXB,SLC45A3,NDUFA4,CYTL1,FNTB,NME4,PDSS2,SLC6A4,TOB2,YIPF5,SFTPC,DSN1,SLC25A23,ZC3H15,PLAC8,CYB5R3,SNAPC5,RPP21,NDC80,RNF26,MAP1LC3A,RAB13,MRPL51,CDK5,GNG3,PATE2,PTN,TMEM31,F10,KCNA3,SSBP1,NDUFV2,ZNF526,NEK2,NDUFB7,APOBEC3D,RAB5A,PC,RAB14,BVES,TMCC1,REP15,GOLGA7,CD79B,WASL,SDC4,SP4,DYNLT3,ZBED4,TLR6,KCTD9,RPN1,CD151,P2RY11,DLG1,IL3,MSX1,CHRM1,HEXIM1,PRDX2,DPP4,MRPS33,LMBRD2,UGP2,EIF2S1,LMO3,PAX6,ZNF507,STAT1 |
| 5.567e-24 | -53.55 | AGR2 (anterior gradient 2, protein disulphide isomerase family member) | protein interactions | 10551 | 930 | 401 | 19454 | 5460 |
LLPH,ACTR2,AURKAIP1,UBE2V1,FBP1,CMPK1,CCT5,PTGES3,HUWE1,RPL23A,RAB1A,SFXN1,RAB3A,EIF5A2,GOLPH3L,DAG1,ATP1B1,TOMM70,CDK9,RPL35A,THOC1,PSMB1,PTPN1,RPL12,RARS1,PICALM,STOM,SLC12A2,UQCRC1,ARHGAP1,RTL4,RTN4,AP2A1,RALB,PNP,COPE,CMBL,CTNNA1,ENO1,RPS11,RPN1,GDI2,NME1,FAF2,RPL29,ACTN4,PPP2R1A,ERLIN2,PSMD12,TMED7,SAR1B,HSPD1,SLC25A5,HNRNPA2B1,HNRNPD,DCAF11,HNRNPA1,HMGA1,PDIA3,PCNX1,PPIA,DHX15,ATP6V1A,CETN3,KRT8,RPL8,RPL9,PSMB4,PSMB5,ARCN1,VAPB,H2AC1,ISOC1,PYGB,CYFIP2,SRM,MRPL57,ATP6V1G2,PSMA3,SPOCK1,HSP90AA1,ARMT1,YWHAZ,RPS29,ACO2,NIBAN2,RAB11A,USP5,ERH,PRDX2,PDLIM3,TUBB,LGALS3,ACTB,SNRPD2,SNRPD1,RPS9,S100A6,SLC25A24,CBX3,GNPNAT1,MVD,ATP5PB,RPL17,PSMA5,CSE1L,HNRNPK,DHX9,PSME1,TMEM123,RPL24,TPM3,GAPDH,ESD,CAND1,RPS27L,DSTN,MTAP,RPL32,ALYREF,HBB,CDC42,RPS15,STK38,PGK1,SEPTIN6,RPL27,SORD,UNC79,RIC3,MTPN,CFL1,PSMB2,SLC25A1,RAB2A,RPL7A,DAPK1,IRF2BP1,RPS23,TUBB4B,H1-3,EEF2,RPS7,RPS4X,TFG,PRPS1,RAB18,PSMA2,HNRNPF,PSMA1,RUVBL1,XPNPEP1,MYO1B,EWSR1,RPL31,ABCF1,POU5F1,DDX1,AK2,YWHAH,YWHAG,RPL6,RAB5C,PTDSS1,HSP90AB1,CCT7,RPS10,HNRNPL,RAB1B,RAB31,ANXA4,MED31,CNDP2,CSNK1A1,PSMB3,EEF1G,PHB2,DDX5,CD34,PEBP1,TMEM106B,CRMP1,SERPINH1,MDH1,ZMPSTE24,CCT2,ADK,H2AZ2,PSMD14,S100A11,PSMD1,UFD1,STX16,APOBEC3B,SFN,HNRNPC,LDHB,PSMA4,PSMB6,CBX5,RPL10,APEX1,TAGLN2,MATR3,RRAS2,PRMT5,PAPSS2,VDAC2,ILF2,STARD13,UAP1,EEF1A1,DDX39A,RPL15,GGCT,AKR1C1,OLA1,ARF4,RNF20,PRDX4,EIF3E,MSH6,BSCL2,PC,HSD17B10,SLC25A10,NSDHL,ESYT1,GLO1,CALR,G6PD,TOP1,SEC23A,AIFM1,HACD3,RPLP0,BORCS8,LMNA,HSP90B1,PSMC4,RPS14,LPXN,SNRPN,TPT1,MBD3,CERS2,EIF5B,HMGB1,RPL4,ARPC2,SQSTM1,CA2,XPOT,NTAQ1,ATP5F1A,TUFM,USP14,NONO,CTSD,RPL22,LDHA,RAB14,TXN,RPL13A,GANAB,RPS20,UBE2I,ACAT1,EIF4A3,CYRIB,STK16,VPS33A,GFPT1,TXNRD1,ACO1,ANP32B,ETFA,ERP29,RPS24,NDUFA4,RPL23,NQO1,PRDX1,PRPF19,PSMD3,STOML2,CACYBP,RAB11B,NOP58,SPTAN1,RPL7,HP1BP3,GATD3,DNM2,PHB1,MYEF2,MYL6,ZNF805,VAV2,PRDX3,ETF1,RAB6A,H1-5,HADHA,RBP5,LMNB1,TOMM40,MCM3,ALDH1L1,AKR1C2,RPL35,AP2M1,RPL37A,RMDN3,ARF1,RAN,PSMC3,GPD2,TFRC,ARPC3,NHERF1,CRABP2,ACTR1A,TMEM205,NAA35,MTCH2,RPL3,ERO1A,ABCE1,IDH1,SLC25A11,TCEA2,RPS2,RPL10A,PGAM1,RPS16,SYNCRIP,EEF1B2,CAMLG,GSTP1,UBE2M,ACACA,IDH2,SAMM50,GTF3C4,SPTBN1,CAPN1,MARS1,HSPA5,PRDX6,APMAP,ATP1A1,MYG1,BUB3,CACNB2,EIF2S2,SGTA,RPS3,CREB1,PSMA6,RPL18,PIR,PSORS1C2,TRAF2,RPL28,KRAS,VDAC1,RUVBL2,PDIA6,RTCB,PABPC1,CCT8,CRYGA,YWHAB,FKBP4,AGR2,PPIB,NT5C2,GSTM3,HMG20A,MACROD1,TCP1,S100A8,CORO1C,NRSN1,POLR2L,ADSS2,PALS2,RPL27A,STAU1,HSPA8,YAF2,RAB5A,XRCC5,H1-10,CHTOP,PCCB,GSTM4,ATP5F1B,PSMD6,CCDC90B |
| 8.274e-24 | -53.15 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 14773 | 4431 | 16828 | 4835 |
FAM110B,STBD1,THAP2,TIAM1,IL4,TRIM63,EHHADH,GLRB,TRIM46,DNAJC1,HCLS1,EMP2,LILRB1,RBFOX3,AVPI1,SSR1,SMARCD3,NETO2,DISC1,CHID1,SF3A1,GNAI3,PSPC1,TRAPPC10,MCHR1,SFN,ZNF596,STX10,FAM50B,COIL,ZFP64,TUBB,SLC6A8,CUL2,PYCARD,TREML1,MED9,SOCS4,MED30,GHR,CXCL11,ASB8,INPP5E,GNB1,GLTP,CDC16,TOMM7,SEPHS1,ANAPC11,LACRT,MAD2L1,CA10,MAP2K6,RASGEF1C,PCMTD1,RBM42,PPP5C,GSTA4,RHBDD3,VPS4B,TMEM160,LDLR,FOXP3,MRPL40,GTF2IRD1,CD1E,TRMT11,CLCA1,TMEM88,ZSCAN5A,B4GALT7,WASF3,PRKCQ,GABRG2,TFIP11,PGM1,NAT9,HADH,RPL8,IKZF2,CLEC9A,NFE2,POGK,SLC16A4,ACOT8,HNRNPA1,TRIM52,LECT2,SKA3,RPS29,ALKBH2,CTSB,NCKIPSD,DEFB121,LRTOMT,COX19,RPS4X,TMOD3,SOX3,PPIA,FBP2,MAP3K12,RSPH1,ZDHHC15,VAMP3,WDR83,CLVS2,CRB3,DHRS7,VLDLR,MTX2,MAEL,CYB5A,TFG,ELOVL3,PHF23,COX10,RNASEK,BSCL2,CDK8,TAGLN2,RPP14,HRAS,WDR20,SYT4,TRIM8,FAHD1,RPL13A,MITF,LCA5L,IKBKB,HELLS,KIF3B,SPCS3,HTRA1,MCAT,NUDCD3,SEC63,NOVA1,INPP5K,ERP29,PTTG1,BCCIP,TM4SF1,IRF2,TACO1,NSA2,CAMK1,WFDC5,NOL7,SNX2,DEFB115,SSBP3,NTF4,POC1B,GPHA2,DTD1,REXO2,MYT1L,USP2,CYB5R1,LRTM2,CYP4F12,CPE,SLC39A13,DCAF4,PCSK2,ARHGEF6,NELL2,NDUFB5,TM2D2,SUB1,SCN1B,CDC40,TRA2A,SATB1,PRMT5,BEND6,RALGAPA2,PCK2,PPTC7,GANC,ACO1,KCNF1,UBXN6,NME2,CD4,SFXN1,UBAC2,SLC25A45,NOSIP,NR4A2,TRIM27,COPS2,LIMD2,GTPBP2,C1GALT1C1,LGI3,EIF2AK2,EIF2D,NEUROD6,AIG1,INSM2,TSHR,SLC25A20,SRGN,KLHL32,STC1,DYRK1A,DRP2,TMEM74,TIMM8B,IRAK1BP1,LMNA,PHF1,DCUN1D3,CYP3A5,CD52,MGAT4B,DCAKD,PLP1,XPNPEP1,RNF41,ZNF7,EXOSC4,BUB3,DNLZ,ZMYM2,SLMAP,CFL2,SNX5,FASLG,KLRD1,JUP,ALKBH3,EXT1,MSRB3,EIF3E,CTBP1,CDC42EP4,PNMA2,ANKRD49,CD38,MT1A,RIMS3,CUTA,RMI1,DLAT,CAMK2N2,MCM8,UTP15,GRM8,EIF4E2,IL13,TLCD2,TAS2R16,HP1BP3,BAG2,PHF12,GEMIN7,ZBTB33,TMEM184C,NOB1,MED17,DCP2,EPYC,GRAP,PLXNC1,UGT2A3,TAAR6,PHC1,BLOC1S3,CBL,LHB,DEFB124,INSIG2,WDR6,ACOT6,IL12B,HSDL1,KLHL23,COPS4,KCNK17,ZGLP1,ANGPT1,NCALD,CYP1B1,MDH1,ELK1,FAM168B,RAB28,COX17,DDI1,RALYL,MRAS,MRPS35,MMP14,RAB6B,ATP6V1G2,ITGA2,SLC31A1,COX6B1,SRSF1,LMBRD1,UCK2,CAV3,EPHA2,FGF7,MAPRE2,CDK2AP2,IGSF21,PRPF18,PIK3R1,ACOX1,FADS2,F7,IFT52,TSPAN7,SUMO1,KDM2A,KLHDC8A,POLD2,EXOSC8,ZNF574,G3BP2,OR2J3,DCLRE1C,PDIA2,SNAP23,FAM76B,RNF146,SAP30L,ELOF1,GGCX,PICK1,NTRK3,TSSK1B,CCAR1,FBXO3,AGAP2,STX1A,GUK1,ACHE,CSE1L,UBE2B,IRF2BP1,NEK9,TNFSF10,FMO3,CDK5RAP3,MNAT1,STAC3,FAM3A,CAPZA1,CLDN6,GAPDH,YES1,GRIA1,CBLN3,CRYGA,SLC25A42,VAC14,CLIP3,HDAC5,FGL2,PI15,HECTD3,GKAP1,UBL4A,MPST,PSMC4,ASRGL1,MFSD6,POU3F4,MADCAM1,TMEM97,MED13L,NSDHL,IDH3A,JRKL,RFC5,RLN3,ANKRD50,SLC35C1,ESAM,PCCB,HSD17B3,NEO1,ACTN4,GATAD1,PTGES3,RGS10,FBXL3,QRSL1,VIPR1,ASB1,RPS15,TCOF1,HSP90B1,RETN,MCPH1,NKRF,ZDHHC8,ISOC1,EDDM3B,LRAT,KLHL28,EDEM3,TPPP2,EGLN2,RNF152,MRPL33,UQCRC2,RBPJ,MRPL17,CXCL9,ATP2B4,SIGMAR1,IFNK,DUSP9,CFDP1,PEX26,BAZ1B,OR4E2,PPP1CC,LRRC8C,DMAP1,NOP16,ZNF32,KCNB1,TNFRSF9,BCL2L1,YWHAG,ICA1,CST3,SCAMP5,PLEKHO2,LYZL4,MYH1,IFT57,VDAC2,DCTN6,ACVR1,CASP4,SLC15A2,B2M,SASH3,TIFA,TPRA1,NR0B1,AMACR,FITM2,TRIM22,CYB5R4,SPOP,DEFB129,DCUN1D1,RPS24,MCM6,NUDT4,ITM2A,DCK,EAF2,ADH1A,SDS,DIRAS1,GINS4,ABCE1,PRRT1,CYP7A1,IL5,PTGDS,VDR,CTTNBP2NL,PSMB2,CX3CL1,FGF22,TNNI1,ADRA1A,PEBP1,VAMP1,CBX7,COL3A1,SLC2A1,QSER1,MYO1B,SRSF12,GPT,SLC6A1,GPN2,TLR4,ADRB2,HS3ST5,PLAC9,SLC38A2,GPR22,NKX6-2,TAF2,SGMS2,NCSTN,ANXA7,SSR3,LIN7C,PFDN1,CCL1,NGDN,CTRB2,PRR19,ANO3,UBE2N,DPPA2,PMP2,EIF5A2,PI3,SMURF1,FKBP4,STX16,PSKH1,TMEM19,SLC35A5,LGI1,CDC5L,CRMP1,TCP1,KCNH8,HPS6,CH25H,RABIF,ADRM1,CNOT7,TAF11,EMX1,PKIB,UBTD2,IREB2,HNRNPL,CD80,PITPNB,SMAD2,CCDC167,NGRN,RAD1,GIPC3,DBNDD1,NFE2L2,POLR2C,GNAQ,LPAR6,PPIC,MMAA,NCOA5,RUVBL2,GOSR1,IGF2BP1,SNX3,CLRN1,DBH,TBC1D5,SIKE1,NDN,ARMC6,CHCHD1,KCNA3,F10,SSBP1,PTN,TMEM31,PC,RAB5A,APOBEC3D,NEK2,ZNF526,NDUFV2,NDUFB7,GOLGA7,TMCC1,REP15,RAB14,BVES,SP4,ZBED4,DYNLT3,CD79B,WASL,SDC4,DLG1,P2RY11,TLR6,CD151,RPN1,KCTD9,CHRM1,MSX1,IL3,LMBRD2,MRPS33,LMO3,EIF2S1,UGP2,HEXIM1,DPP4,PRDX2,STAT1,ZNF507,PAX6,MAMDC2,TSG101,ADCY2,MOBP,PKIG,DRG2,THBS3,TRUB1,CALR,SNAI2,HEXB,PPFIBP1,SYNGR4,CYTL1,NDUFA4,SLC45A3,SHMT1,SLC6A4,PDSS2,YIPF5,TOB2,FNTB,NME4,SLC25A23,DSN1,ZC3H15,SFTPC,RPP21,SNAPC5,NDC80,PLAC8,CYB5R3,CDK5,GNG3,MRPL51,PATE2,RNF26,RAB13,MAP1LC3A,STXBP6,TPBG,KCNQ5,PDE1A,DAPK1,LILRA1,SLC25A17,NFYB,ZCCHC12,ARRDC3,LRWD1,CDSN,SESN3,YWHAB,THY1,TESC,ZNF692,SLC25A44,TBC1D24,ST6GALNAC3,EDNRA,PHB2,MMADHC,TTC1,NR1H2,BMP1,PRPF31,LEPROTL1,TMEM95,SPOPL,SYT2,GNA14,CXCR6,CISH,TXNL4A,USP14,NANP,TSC22D3,ASB3,CHMP5,EIF2S2,ZMYM4,BTG1,AGPAT1,CNTNAP1,ANAPC13,TMEM176A,HDAC6,PBLD,RNF39,DUSP26,EYA3,GTF2A2,ACTL9,MICB,TOR1AIP2,STOML2,GPR15,COPS7A,PPARA,RNF20,RPL35,POLR3F,FRS3,RERG,TPT1,SNCB,ATL1,RRAS2,MAGOHB,TM9SF1,COMMD2,PEX5L,CBX5,MYCT1,ARL10,FAM118B,GABARAPL1,CD46,TRMT1L,KCNMB1,UCK1,CDC123,GNAI2,TRIM11,VMO1,C1QL3,MRPS18A,RBM18,TOPBP1,QPCTL,MTG1,RPL3,GLRA1,G2E3,NRSN1,HOXB1,MAX,TMUB2,RHOB,YIPF4,CSNK2B,FLRT2,BOLA3,DEDD,CDC42EP2,PPM1G,E2F4,MRPL52,FCF1,MYD88,CD1D,GLYAT,GFI1,TMEM209,DNAJB6,ZFAND2B,KDSR,CD1B,GCC1,LRRN1,DNAJC27,CRKL,ATP1A1,TGIF2LX,STARD13,B4GALT1,AOX1,PSMA5,CNPPD1,NLRP1,CENPP,RP2,STX12,FBP1,GZMK,TMEM199,TMOD1,TNFRSF14,TXNRD1,KATNAL1,GSTK1,NAE1,RPS11,KCNMB2,GTPBP1,DNAJC25,NDUFA12,NUDT5,AZI2,ILVBL,ARL15,EGFL8,SLC22A12,SNAPC2,CCHCR1,RPS5,SLC1A1,PDE9A,CCDC71,CYTH1,UBN1,TPSG1,UBE2F,FOXP2,CYP17A1,ADNP,LAMTOR1,RAP2C,DDX5,EIF4A3,GTF3C3,RNF14,CSTB,MCHR2,KLHL7,DET1,ZNF330,DNAJC10,RGMA,RAF1,IRF6,GPNMB,PRRG1,SAT2,PHKA1,ALG2,MBLAC2,SCYL2,COG1,RPL10L,GPR26,IL1B,SYS1,FUT1,DOHH,BAP1,PLAA,LRRC4,DRAP1,MEF2C,ARL4A,ARFGAP3,LITAF,GPSM3,TP53INP2,LAMTOR3,ZNF175,SNRPD3,ELAVL4,RPS27L,SEC61A2,STK11,COMT,TESK2,GOLPH3L,TNNT2,ANGPTL2,LY6G6C,RHCE,SEC62,FGF12,RIMKLA,GPX4,EXOC1,FKBP10,PHAX,BAALC,BAK1,ATP1B1,ELK4,FAIM,SMARCA5,CNPY4,DRAM1,VKORC1L1,IL1RAP,FZR1,RILPL2,SLC22A8,DRD1,SMAD4,SLC1A3,GPR85,PPP2R3A,GPBAR1,ITGAV,MXI1,USP5,FERD3L,LRRC1,TCEANC2,TM9SF4,AKR7A2,AURKAIP1,FOXP4,RNF126,TMEM182,LDHB,RPF1,UBE2M,PIR,TRIM10,SLC6A12,UBE2E3,AGAP1,ISCU,FCHSD2,ELAVL2,MOSPD1,RAB22A,AK5,TNNC2,GTF2E1,SMC4,KBTBD4,PNO1,CYP2F1,PSME1,CLVS1,FAU,SSRP1,TTC32,TWSG1,MED21,PSMC1,DNTT,GOLGA5,RLN2,HPGDS,NDUFS3,GIMAP4,MORN4,TBC1D4,UNC119B,RPAIN,SYVN1,HSCB,CES5A,TFEB,ARMC1,GABRB2,RERE,GRID1,CCDC122,PPP1R12A,IL6,FGF10,TLR2,LGR4,HECTD1,DYNC1I1,PPP4C,PPIG,NRBF2,UBFD1,NAA35,GSTM2,GGT7,GRXCR1,PSMA2,DNAJB2,EFHD2,RAB30,RSAD2,NICN1,COMMD5,SST,PFDN4,GABRA2,CNR1,NPY,CAMLG,PLA2G12A,MFN1,ZBTB2,DAD1,TAS1R2,SNX18,TYW3,LNX2,RFC2,ZER1,CNTN1,GNB4,CPNE1,DDAH2,MATN4,ACTB,RPS13,UGDH,AP2S1,PGAM1,RNF121,CHCHD3,NFKBIB,MMP21,ZNF280B,EID1,EPO,DCUN1D5,FNDC9,PPIH,HDDC2,LPAR1,CD1A,HSP90AA1,PTPN22,SOCS3,FOLR2,PDRG1,IFNA2,IDH1,TUFM,GNG13,RASL10A,METTL6,CD2AP,SRC,VPS28,MPZ,SLC35B4,MKKS,PIK3R3,LANCL1,MORC4,CISD1,BAHD1,DHRS7B,PTGER4,TOMM20,TRAF3IP2,PIP5K1A,IZUMO1,PEG10,ZCCHC17,PSMB6,CHRDL1,NLRP6,CKLF,CCT7,PSMD12,HNRNPD,MS4A7,KCTD15,SLC25A11,CDC42EP3,RNF115,MCM3,RAB33B,SECISBP2L,IFIT2,RGS19,RCE1,MGAT1,RASGRP3,ENTPD3,FCGR2A,NAA50,CELF6,RPL7,YTHDF1,TUBA1A,SH3BP5L,MED31,UNC50,ICAM3,LUM,SEMA6C,CCDC85B,MTMR6,NEUROG2,CHST11,HMX2,FLRT3,TNFSF13,FTL,TMC7,LRIF1,STIM1,GRPEL2,FLCN,CXCL12,MSL2,SLC25A28,SLC39A3,SERPINI1,IDO1,PPM1D,KLHL12,CD248,ZNF668,RSRC1,RPL35A,ARHGAP5,CCL20,MRPS7,ZNF575,SPATA6,GLT8D2,FAM162B,VTI1B,TCAP,EIF4E3,MYOZ3,LIN7B,PCDH9,ZRANB2,ARHGAP25,DES,RIC3,SCPEP1,NSFL1C,TMEM190,NDUFB10,POMT2,POLR2F,NMI,SCN3B,LRRC57,PLSCR4,MOG,IFNGR1,NDUFA2,RIMS4,HMG20A,BTF3L4,ARL6IP6,TLE1,IL15,MRPL10,YBEY,NTPCR,PNOC,CYP27B1,NIF3L1,TMEM14B,GNG5,UTS2,RRN3,DHPS,GNB3,HINFP,NUFIP2,CMC1,TMEM229B,ITGB8,BTG2,VAV2,CCDC3,LRP10,NR1I3,TRIM44,PQBP1,GPRASP2,PPWD1,FHL3,TICAM2,FAM20B,HSPB6,GNA11,SERTAD2,HSPA5,NRM,THAP8,WDR45,CRYBA1,MPV17L2,LRRC28,TCEA2,PARD6A,NPC2,TMEM115,PNPLA4,RNASEH2C,HSPD1,EIF1AX,DDR1,SPG21,TIA1,SLC22A6,CAP2,TMEM81,EXOC3,SAP18,BOLL,MX1,GLOD4,PIGA,THOC3,ATG9A,ZNF622,S100A11,VPS54,SLC25A27,TGFB2,RBMS2,IGFBP3,GADD45A,GRPR,RUSC2,CD9,BTG3,TMEM183A,DPEP3,RAB6A,CTTNBP2,RGN,PLAC1,SCAND1,PSMD7,SIN3A,CDK7,ZNF428,PDE2A,TNFSF8,CDIPT,PYCR2,PMPCA,TLR8,ARFGEF1,MED22,NOG,CRY1,CD40,AIP,SLC6A2,TNFSF15,TMEM107,RPA2,GADD45G,YPEL4,LDB2,TAB2,SRPK2,RGP1,CCDC90B,TRAF3IP3,PIWIL1,PRCP,EID2B,CPXM1,THAP1,CD34,FBXL4,DCTPP1,OR4A47,SUPT5H,PDCL,TRIP4,RPL10,STAR,GLCE,SSNA1,GK5,SPINK9,SLC25A24,IP6K1,PTGFR,IL2RB,ST3GAL2,TAS2R7,CD209,FBXW4,MSH6,RAP2A,PPP1R11,MDFI,ZDHHC16,TEX261,POLE3,GP9,RNF10,POLR1D,GPR160,DTWD2,PSMD3,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,RPL18,GIN1,TKTL1,ROCK2,FUBP3,KCND3,VPS72,KRIT1,TBCCD1,TRAF6,CCDC106,ETNK2,CLDND1,RPS10,SPRY1,FUNDC1,AP1M1,ECHDC1,UBA52,TMEM196,TADA3,TRAM1,IMPA2,SP1,ITM2B,MTCH2,MDC1,TRAPPC6A,MGMT,RBP2,AQP11,TLCD1,SSBP4,RASSF8,KCTD17,CLEC6A,PSEN1,MAGEC2,LCORL,EDA2R,FKBP1B,LMO2,FAM161A,ANKRD6,PDE12,YTHDF2,DIRAS2,ACER3,MREG,ARHGAP12,EIF5B,PFKFB2,SRFBP1,TAPT1,TYMS,MED10,ZFAND6,SCML1,SLC12A2,RPS20,RUNX1,GJC1,NAA16,GHRL,VPS18,CIAO1,ATP8A1,KIF3C,SUCLG2,PDE7A,DUSP3,ZNF581,RXRG,SNAP25,CCR7,IGF1,TTC9C,PELO,GMPS,THUMPD1,GORASP2,GALNT2,IL18BP,RASL12,ANXA4,CMA1,DLGAP4,GRIK1,RRAGB,SNRPE,LBX1,NKAP,LRRC8A,GNGT2,SSPN,CNPY1,HAUS2,GALC,ELFN2,RP9,KCTD3,PIH1D1,RDH11,MPG,TANK,SYNGR3,BRAP,DMPK,CDC23,MBD3,FAM136A,SLC35E4,FAM151B,ZNF518B,MACROD1,CYBRD1,ADCK1,WSB1,LYZ,TOPORS,SLC25A5,PRR13,IRF7,PTP4A2,FAM3C,MFAP3L,SLU7,VEZT,RPE,SULT1B1,KLHL25,TMEM165,CENPL,NUCKS1,IER3,CYTH4,IFT172,CPNE2,TMBIM1,RAMP3,KLRC2,TOX4,FXN,UPRT,SUPT3H,FEM1B,MRPL9,UBE2G2,MECR,SGIP1,MRPS17,NBN,TNFAIP8L1,VMAC,IL2,SEC13,TYROBP,WDR11,NHEJ1,FHOD3,SLC35B3,AIPL1,PEX13,TBC1D25,SNRPG,XRCC5,ACCS,TIMP4,WDR5B,ZDHHC4,CDC20,TRIM45,ATAD1,DUSP21,IGSF11,CYP2C9,MRPS34,SGMS1,RBBP8,MGAT4A,FBXO8,NDST3,SLC19A3,CDC7,MPPED2,PRL,CCR4,CHRAC1,KLF3,SNRPB2,LZTFL1,TFB1M,NUDT9,CYGB,PPAT,IL17F,TNF,GGH,PARP2,NF2,ABHD12,BANF1,SESTD1,CARTPT,KLHL1,FOXA3,CGGBP1,PHF13,RPL26L1,PRKCE,ZNF451,WDSUB1,GNRH1,TSPAN17,PRKRA,COX6B2,RNF133,TMEM170A,TAS2R13,DBR1,RHOBTB3,HGS,POLDIP3,POLR2L,FSTL1,UBE2E2,MT1E,LRRC40,DPH3,CRISP1,ELK3,CD81,NPM3,TMEM38B,TSPAN15,GSTM4,CRTC2,PSD2,GH1,PEBP4,BAX,ATP1A3,NUDT2,FEM1C,COCH,RPIA,VTA1,COX6C,PICALM,LST1,XAF1,PIK3AP1,ANKMY2,CNN3,CPT1B,RBM27,ZBTB39,ADORA3,APEX2,TAB1,SF3B1,AKR1B1,TMEM47,MAD2L1BP,LY96,AP1S2,NDUFS2,TMEM185A,CDH11,PSMC3,JAKMIP2,SNRNP40,FAM83B,PIK3CA,IVNS1ABP,BCL6,SSX2IP,DLST,GTF2F1,GSTCD,E4F1,TMED9,SGTA,MTDH,USP6NL,CA2,SNX10,ZNF263,TPPP3,TMEM89,PRNP,CAND1,HSD17B10,GABRA1,MIS12,HS2ST1,GTPBP8,CBX3,DR1,ASPA,BCL9,LYPD6,ELMO2,TRPC1,BOK,TNR,TM4SF18,STARD3NL,YWHAZ,ICAM2,ABHD8,SLC8A1,LSM14A,CAPN2,CCNA2,TM4SF20,RNF222,REEP4,AASDHPPT,SLC29A1,SURF2,GJA1,MAGED2,TAF1D,KCNJ10,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204,PROS1,EWSR1,B9D2,MTRF1,ZNF592,TRIM24,TGFB3,ACSL4,MRFAP1L1,CIB2,YAF2,ELP3,MRPS16,ABHD14B,EED,DUSP19,NME1,STMN2,RGS2,NOS1AP,BCL10,KCNMA1,MBD5,PDHA1,ADPRH,RBM7,TRAF2,KCNK13,PCDHB1,ABHD4,BRCA1,DPY30,CNNM4,NR1I2,NPR2,CDK4,STOML3,TSN,STAU1,SERINC3,SLC41A3,KLK6,FKTN,DNAJC3,RNASEH1,TMED7,ST3GAL1,CSNK1A1L,SOX2,IL18,DERL1,DPEP1,UQCRH,PRKAB1,KLC2,STXBP1,PAX9,PCMTD2,MTHFD2L,IRF3,PYROXD2,MRPS21,TAS2R40,LRP6,RAC2,LCA5,STK24,POR,ST3GAL5,IFRD2,CEP97,ZNF501,PARP11,SLC32A1,SAT1,CSGALNACT1,R3HCC1,SLC35D1,SMU1,RMI2,COL1A2,JPH4,AMIGO1,TOR2A,PTS,MAP3K11,MBL2,METTL14,VAMP5,EDEM1,GNG2,UHMK1,LCP2,CRTAP,ADIPOQ,ANKRA2,ERH,ALKBH5,CRYBB2,NDUFAF4,AKAP14,FAM162A,CTDSP1,CCNB1,ABHD6,CLDN1,METTL2A,TFCP2,RDH10,PDCD4,LDOC1,GPAM,PRPF19,CREBBP,HTR1F,GPX6,POPDC2,GREM2,TGIF2,RPLP2,CDC42SE2,ACBD7,FAM98A,TRIM54,ACAT1,KDM4B,TMEM184B,ZNF287,RAB3D,LAMB2,SLC13A5,CLDN4,GIT2,NKIRAS1,CXCL3,GTF2B,SDF2L1,RUVBL1,NRSN2,TMEM144,TOP1,APOO,BCS1L,SNX17,GPR137,NDUFS8,CYP2C18,MYO6,GCNT3,NKX3-1,F9,BCL7B,TOM1,SEC61B,GPR65,TCF23,GBE1,CHGA,DNAJC22,EIF2B3,TMX3,HTR5A,SFRP4,RGS7BP,CDKN2AIP,FCN2,RER1,MRPS23,FUNDC2,CSRNP1,SYP,ATG4A,ZNF862,POLE4,HSP90AB1,ISG20L2,GPHN,IPO8,TMSB10,ATAT1,ARMC7,CIDEB,TMEM123,ZBTB5,ZC3H7A,AIF1L,DSTYK,ZNF821,DDX50,GTF2H5,RPRD1A,VRTN,HINT3,SLC25A10,STK4,PPP2R2C,BST2,PLS3,CYP1A1,ST8SIA5,TNKS,SLC22A17,IL1R2,TMEM41A,FAM181B,NKIRAS2,ACVR1C,PIP4K2C,STUB1,KLF9,AVPR1B,ST7,TRAK2,SERPINB1,SRSF2,UBLCP1,GSTA1,SNRK,TEX264,CSH1,UBL5,BTN2A2,IFNB1,KIAA0513,SEMG2,CCNH,UBASH3B,POLA2,POLB,MNS1,TOR1B,SPSB3,LTA,MRPS9,ABCG2,FAM83C,MTF1,PTH2,PPP1R1A,RPL27,MSTN,PRICKLE2,CLDN9,VGLL2,SLC16A10,DIO1,TRMT112,SYNCRIP,SLC35F2,TCEAL1,LTB,PFDN2,USP16,TMED5,HARBI1,SLC25A12,HMGCS1,CLCN6,AK3,PSMA1,RPL32,DDRGK1,HDHD3,SHOC2,DTWD1,ATXN10,ASTN1,NCBP2,SOD1,TBC1D13,SMPD2,CCR1,REN,FAF1,VEGFA,TP53INP1,IQCK,AVL9,DECR2,PTPN11,SOBP,NOTCH2,NAPA,CRAT,TM4SF19,TMOD2,GNPDA2,TSNAX,POLR2B,LRRC61,UBIAD1,GTDC1,PARL,DHRS13,GPM6B,REG1B,FBXO22,RFC3,SLC7A8,ATP6V1A,EGFL7,TMEM59L,SERPINC1,ACP5,HLF,KLF4,COPS7B,DENND2D,ACBD6,RNF34,ATG7,NPW,TUSC1,NFKBIA,PREB,PRDX1,FAM53B,TAF10,LRRC8B,ETF1,TRIM68,SCML2,DNAJC19,VGLL4,CHKB,CCNY,ELF5,CLDN12,PKP4,GPR176,CRHBP,CNOT2,GSTM5,ERAS,PLEKHO1,MYBL2,ZNF326,ASB7,PRKACB,GLRX2,LANCL2,APOBEC3H,FEN1,CLPB,VDAC1,KLF1,ADD1,CLEC2B,CBR3,STARD4,THOC2,FLOT1,DROSHA,NR2E1,MCM4,SCNM1,DCTD,FAM177A1,IGF1R,CX3CR1,SLCO2B1,PDAP1,SOX14,CHMP4C,KLHL22,MAVS,UBP1,CD1C,RAB19,UMPS,CDCA7L,MRPL22,SS18,EPS8,RFXAP,UPK1A,HOXC4,SIAH2,CHCHD6,POLR1B,CER1,IFIH1,NUDT7,FCGR2B,BIRC2,MTM1,PRMT6,PMM2,TTL,TMEM70,MPDU1,VAMP8,TIMP3,PPP3R2,PRSS12,GABPA,FKBP8,KLHL24,PPP2CB,ZNRF1,CHST13,CLEC18A,SMAD1,AQP2,PPAN,IL2RA,RCL1,FBXO7,RABGGTB,SLC2A3,SEMA4C,HP,CTTN,STOM,RPL23,CLLU1,SPIN3,TGFBR2,CDNF,TNFRSF1B,METTL22,CYP2C8,ASZ1,CAPN1,USP3,GSTP1,LLPH,CCL2,PPM1K,AR,IFI6,LAMP2,RNASE1,TMEM45A,FAM43A,NLRP9,RIT1,GPX7,CHRNB2,PTPN4,EFNA3,TPM3,SNRPB,ELOVL1,SSR2,MORC2,SOSTDC1,FPGT,LRRC3B,EIF4A2,MAGEH1,PRDM4,FEZ1,STAT5A,COPS5,HSD17B6,PLCB2,MAP2K1,APOBEC3F,RNF8,PEA15,ADAMTS10,EP300,TMEM30A,AFAP1L2,B3GALT1,COMMD6,KCNJ3,GNPDA1,IMP3,UBL3,NCDN,GNAO1,MRPL34,NDUFB6,TMEM170B,TMEM117,SNX22,SFXN2,CST11,FASTKD5,SRSF7,EPCAM,PCDH17,TAGLN3,STAT2,SAV1,IL22,PRR3,GLRX,TOR3A,CBLL1,UBA3,BFAR,TOMM22,TMEM179B,CSTF3,HENMT1,RPL7L1,CSGALNACT2,ST6GAL1,STX11,SERPINA1,PMP22,LARP4B,ANKRD34B,HSPA13,NPSR1,LMAN1,SLC11A2,UBB,PPP2R5E,SH2D1A,SCLT1,MRPL11,DAAM1,LRRTM3,NPPC,PSMD4,RPS7,GRAP2,RAB27A,RELL2,TRIM15,FBXL14,RHEB,DHX15,DDX46,PDHB,MLC1,ZNF664,MAT2B,XCL1,BBS5,RPS6KA4,GANAB,TSPAN18,SLC6A6,SLC30A7,TCF19,CCDC134,MFSD5,FGFBP1,MRPL18,METTL21A,PSORS1C2,POP5,CHAC2,G3BP1,PCDHB13,RPS27A,DSTN,DAPK3,ELOVL7,DBT,RAPGEF5,TPD52,HINT2,TMEM101,NUF2,SLC16A1,CHIC2,CHCHD4,SUFU,MTA2,CCDC86,MRGPRX3,FBXL19,LAPTM4A,KCNC1,SLC38A7,PGGT1B,KDELR1,TOM1L1,RRM1,RBM22,KRAS,RPS16,ILF2,BAG3,ZNF365,PSMB1,CRIP1,ZMYM3,CNTN2,ASNSD1,NR2F6,HERC4,DKK1,NDUFAF3,CHPF2,IER2,RASD1,CCS,NLRP3,ILDR1,SHISAL2B,SCGB1D1,PPP1R1B,RND2,COMMD3,BMPR2,SCG3,OLFM3,ADAM21,CLDN3,MGAT5B,PTAR1,THAP7,UAP1,RLIM,PTEN,DEPDC1B,INO80E,CRLF3,UCN,CENPW,FRRS1,ATG4C,SNRNP48,GFPT1,SDHB,TXNDC12,RWDD3,EPHX1,ABHD5,CXCL13,CKS2,RORB,NEGR1,FDFT1,SIT1,RPA3,MOXD1,GNG10,SMG9,MUL1,NRN1,MAPRE1,SEC22C,MME,METAP2,ZFAND2A,APOBEC3G,NTRK2,GNG12,USP15,ELMOD2,FKRP,LPAR2,CNRIP1,SIAE,GAMT,ISX,RTN4,GLRX5,GNAZ,ARG2,DNAJB9,RNF144B,CHST2,HNRNPA0,IKZF5,FZD3,CD247,RHOBTB1,NDUFS6,TMEM126B,CTSC,CDAN1,SPRED2,DDX23,PCNA,PIK3R2,PDE1B,UBE2K,PCYOX1L,CREG2,PLD3,AGPAT5,DNTTIP1,HR,LRRC3,DKC1,ARPC3,FBXO44,FBXW11,CINP,PPFIA2,CNDP2,THBD,BCL7C,IL1A,TYW5,CBLN2,NUDT12,RPL27A,HTRA2,NDUFAB1,JAGN1,SNAP29,PTK7,DHX38,GPR171,COX8A,LGALS8,USP8,TMEM147,NEUROD2,METTL15,PGRMC1,SAR1B,CAPG,TLR1,IL12A,RHAG,DHRS1,HCST,FBXO34,BRMS1L,ANAPC16,ZBTB16,CHORDC1,NAA15,SYBU,EXOC5,SERPINB6,ADK,G6PD,F11R,FTHL17,WDR55,RALA,TLR7,GAPT,VASH1,PPP2R5A,RNF128,PTGES,ACADS,GNPTG,ENO1,RPL24,CRYL1,SERPIND1,CHST7,SLC25A14,PRDX4,MECP2,ZNHIT1,TFPT,ALOX5AP,ELOVL6,RGS6,CSTA,CLSTN3,TBC1D19,RASL11A,LYPLA2,SNRPN,TSPO,DCAF4L2,RPRD1B,RNF181,POP7,STYK1,CYP11B2,FBXL7,LBR,CELA3B,GPD2,TRMT61A,RHBDL3,CAMP,COX5A,THNSL1,SLC1A2,PHF21A,SETD7,PPIF,DUSP6,MTHFS,DAG1,ZBED3,CYB5D2,RPS12,MAF1,TXN,ARF4,SCGB1C1,GABPB1,TNFSF12,CALY,RDH12,TAX1BP3,ZNF790,PSMA4,DNASE1L1,GABARAPL2,PML,EIF1B,MT3,SERTAD3,NECAP1,GPC4,MZT2B,LIMS2,HBA1,GADD45B,SENP8,STX7,MGST2,PPM1B,PKIA,TRIM35,TRAFD1,INMT,NFKBIL1,CRELD1,TP53,KIN,AP2M1,TAX1BP1,PRDX6,HSD17B1,HEXIM2,TBC1D17,TMED4,SLC25A46,FCER1G,CYB561,BET1,IRF8,RWDD4,KPNA6,PTRHD1,TOX,SYNDIG1,GSTM3,FTSJ3,TSEN34,SPSB1,RBBP9,FBXO11,DGCR6L,WNT10B,ETFB,VIP,LRRC8D,NTNG2,ACTR3B,ZNF22,TFDP2,C1D,ZNF189,EEF1B2,RBM15B,MIF,HRH2,AP2A1,APTX,TMEM45B,BCL2A1,ZNF688,SPINT2,KCTD12,UQCRQ,RPL12,CD83,DNAJC7,ICAM1,PLCL1,MTMR2,YWHAH,GABRB3,FAM187B,MRPL49,ADAMTS20,GFOD2,SOD3,DUSP22,LSM2,CCT8,TMBIM6,FOXI3,UTP6,SH2D5,HMGA1,GGPS1,TSPAN11,MND1,IPCEF1,ZNF267,IDE,TFRC,TTC8,AUH,C1QTNF1,HSD17B11,ZNF177,ZNF652,LUC7L3,HHIP,MAP4,LGALS3,NMBR,CTNND1,LCN12,FAM91A1,DDIT4,SMYD3,RAB3A,CA8,YIF1A,RPS3,LRRC20,EGR2,HAX1,CALU,AIF1,HBEGF,CHN2,TMEM60,USP30,UFM1,RAD23B,FOXJ3,ARPC2,CLEC7A,APPBP2,GPR146,KCTD11,GINS3,MYL12B,PID1,SRSF4,NECAP2,SH3BGRL,EXOSC3,IL7,ZHX3,SDCBP,MED23,USP13,TMEM42,SNX33,NDP,ERLEC1,CEP85,SRPRB,FGF3,DRG1,SNX12,POLR2D,NEURL2,PDP2,SMNDC1,CNTFR,KRT222,PI16,BHLHE40,MAP1S,GLRA2,RPL29,NLRP2,MRPL53,HDAC3,GDPD3,ARPP19,ANAPC4,FABP4,COX4I1,MPHOSPH6,TOMM40,GREM1,LRRC4B,SDC2,CTDSP2,RPL10A,FAH,ACVR1B,ACTR1A,FITM1,LAT2,SNX14,AIFM1,COQ10B,POLR2G,RAD21,RAP1B,DNAJB4,TXNRD2,C2CD2L,TIMM8A,KLHL9,NPC1L1,CARHSP1,ABCB9,FAS,ATF1,RBBP4,COX6A2,POLR3GL,MAD2L2,UBTD1,TMPO,ARMCX3,COX16,CUL3,CCDC92,AKT3,MAN1A2,POLD4,ERVFRD-1,EIF3D,DNAJC4,RBP5,CHMP2B,ELOVL4,GRB10,SKA1,TST,RNF5,DGCR8,RPL9,API5,SPRYD4,KCNS1,TPH2,CRYM,SAMHD1,ZMAT2,NT5C2,DOLK,EHD3,ST3GAL4,MRPS18B,DNAJC30,FKBP1A,SRXN1,ENC1,KCNJ8,SAMM50,FOXP1,SLC4A10,HOMER1,PDE8A,PSMB9,TRIM6,PYGB,SLC20A1,ALPL,RCCD1,EXTL2,EFHD1,C2CD2,LAP3,ADIPOR2,COX11,CLIC4,NPTX1,HMOX2,HNRNPH2,ADM2,ALDH1A3,AHCYL1,IZUMO4,TESK1,DVL2,TMEM108,BRD3,SURF6,FAR2,C2CD4C,TTC33,RPL39,UCHL3,EEF1A1,TRAPPC4,GAS2,MMD,WRAP53,KLHL26,BET1L,PRKCA,TFPI,IL2RG,PIWIL3,CCM2,ALB,PSEN2,SLC35F1,SNX1,FTH1,SLC25A26,SYK,ACO2,VPS16,CLN8,DUSP10,BACE1,SLC38A1,SLC48A1,CDC42,TNFAIP8L3,MORF4L1,TMEM174,NLGN1,PCBD1,TTC23,AGR2,CACNB3,AGA,CD63,LCN8,CPSF4,DNAJC24,AKAP1,CLEC1A,KBTBD3,PCSK9,PSMA6,HEBP2,SP2,VAPB,PNMA1,CALML5,TCF21,CNKSR3,CASC3,SLC6A3,TUSC2,SEC23A,GEMIN8,TIRAP,RPS9,MYL6,TOP2B,PSMG3,GPR173,PPP1R8,SHISA2,KCTD10,RAB35,MAB21L1,CCL28,MKLN1,CMTM6,VPS26A,EEF1E1,FEM1A,CD40LG,SEC11A,TMEM50A,SMG8,LILRB4,MYC,ENO2,SLC2A8,PSENEN,CD86,PNMA5,MANBAL,FARSA,UBE2H,PTPMT1,KBTBD6,ZNF704,RANBP6,G6PC3,SLC25A39,CD14,PRR5L,CYP2R1,GOSR2,SLCO1B3,FGF23,SFRP1,WSCD1,ELF1,TMX2,HTR1A,CCL27,ZC3H11A,KDELR2,DAP,DDX1,RPS26,RNF40,TP53I3,RNASE6,DPM2,BRIX1,IRGQ,CFL1,KLHL3,MCMBP,APBB3,SEMA5A,AGTRAP,CRADD,PPP1R3C,KCNAB1,TMEM11,FAM169A,TNFAIP1,S1PR4,CNOT6,CHPF,REEP6,MATR3,LAMP3,DNAJC2,GNB1L,ATP1B3,ZNF473,SELL,KIAA1143,GNL1,ROMO1,PPY,CRYAB,TAF7,APOC4,RNF11,CYTH2,SYNGR2,NAB2,FXYD6,ZBTB25,CD28,WDR82,TLR10 |
| 8.274e-24 | -53.15 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 14773 | 4431 | 16828 | 4835 |
PDHA1,ADPRH,MBD5,NOS1AP,BCL10,KCNMA1,RGS2,STMN2,NME1,DUSP19,CDK4,NPR2,NR1I2,CNNM4,DPY30,BRCA1,PCDHB1,ABHD4,RBM7,TRAF2,KCNK13,STAU1,TSN,STOML3,RNASEH1,DNAJC3,TMED7,KLK6,FKTN,SLC41A3,SERINC3,DERL1,IL18,CSNK1A1L,SOX2,ST3GAL1,MTHFD2L,IRF3,STXBP1,KLC2,PAX9,PCMTD2,PRKAB1,UQCRH,DPEP1,STK24,LCA5,RAC2,LRP6,TAS2R40,MRPS21,PYROXD2,SLC32A1,PARP11,ZNF501,CEP97,IFRD2,ST3GAL5,POR,SPECC1L,KHDC1,NAT2,RINT1,BZW2,TSPAN5,OR10G9,ZBTB17,BCAP29,FABP7,CD274,CREB3L4,B3GALNT1,EIF3K,SNAPC3,BLOC1S2,SNCG,IGBP1,AKAP12,SSU72,DDX39A,RAB40AL,TMSB4X,EIF4E,TRIM5,LHFPL4,COX4I2,CDKN2C,RNF113A,EFNB1,PREPL,SH3GLB1,THTPA,TSPO2,GOLGA7B,ITGA6,CSNK1A1,PELP1,COMMD8,TFE3,IFNA10,DEFB114,MT1M,FUT9,PHYH,NTN4,RTKN,RPLP0,UBE2V2,IL10,GMPPB,CALHM2,ADO,CCDC25,TES,LMNB1,BECN1,EMP3,CHMP2A,VMP1,CBR4,SLC19A2,MSMP,HSPA8,B9D2,EWSR1,PROS1,TMEM204,EED,MRPS16,ABHD14B,ELP3,YAF2,ACSL4,MRFAP1L1,TGFB3,TRIM24,CIB2,MTRF1,ZNF592,GPR137,BCS1L,SNX17,APOO,TMEM144,TOP1,NRSN2,F9,NKX3-1,GCNT3,MYO6,NDUFS8,CYP2C18,GPR65,SEC61B,TOM1,BCL7B,HTR5A,TMX3,DNAJC22,EIF2B3,CHGA,GBE1,TCF23,SYP,ATG4A,ZNF862,CSRNP1,MRPS23,FUNDC2,RER1,FCN2,RGS7BP,CDKN2AIP,SFRP4,GPHN,ISG20L2,HSP90AB1,POLE4,CIDEB,ARMC7,ATAT1,IPO8,TMSB10,DSTYK,ZC3H7A,AIF1L,ZBTB5,TMEM123,COL1A2,RMI2,SMU1,SLC35D1,CSGALNACT1,R3HCC1,SAT1,EDEM1,GNG2,METTL14,VAMP5,MAP3K11,MBL2,PTS,TOR2A,JPH4,AMIGO1,ERH,ALKBH5,ADIPOQ,ANKRA2,LCP2,CRTAP,UHMK1,TFCP2,CLDN1,ABHD6,METTL2A,CTDSP1,CCNB1,FAM162A,AKAP14,CRYBB2,NDUFAF4,TGIF2,GREM2,POPDC2,GPX6,HTR1F,PDCD4,GPAM,LDOC1,CREBBP,PRPF19,RDH10,TRIM54,ACBD7,FAM98A,CDC42SE2,RPLP2,ZNF287,TMEM184B,KDM4B,ACAT1,SDF2L1,RUVBL1,CXCL3,GTF2B,NKIRAS1,GIT2,CLDN4,LAMB2,SLC13A5,RAB3D,RFXANK,TRAM1L1,PLAGL1,SESN2,KLHL15,RABL3,ISCA2,UPF3B,ZNF576,GCA,PPP1CB,TRAM2,MPV17,FCHO2,CHST1,EHD1,ZNF609,TMCC2,SELENOS,KCNK10,SLCO1A2,SRP14,TMEM106C,PLEKHA8,KRT7,MANSC1,GJB2,WDR3,CRYBB3,TMEM203,TAS2R5,FOXS1,PTRH2,ACTR2,ACP6,SYNJ2BP,TMEM164,BICD2,CREB1,SERPINA5,KIAA0408,RNF122,RAN,RPP25,RBM12,GLIPR1,SQSTM1,TMEM177,FMO2,CXCR4,HSPA14,NPY5R,POLR3B,BRD9,PGR,HAND2,KCNH1,CCL17,KIAA1191,DLG4,GTF2F2,DDX42,SLC7A14,GMPPA,CYB561D2,MT2A,PPP1R16A,PXMP2,ATP1A2,CLDN8,CXCL14,ADAMTS1,TUSC3,RPL6,BNIP3L,NFKB1,PRKAG1,HNRNPK,LHFPL2,ACAP2,SCD5,MAFG,EGLN3,CLDN22,DYRK2,FOS,MRPS28,RIOK2,POMP,RPL26,TPPP,RFTN2,RB1CC1,CAPZA2,SLC35E1,CCL8,YPEL5,PPID,HNRNPA2B1,GGCT,RCBTB1,ATP6V1C1,OR2A25,FANCG,STX6,PLA2G15,MAPK1IP1L,RHOJ,CBLN4,WWP1,TMEM50B,IFNG,JUN,CD47,S100A8,HIRA,SUMO3,ZNF687,CCR3,RAB23,CMAS,SFT2D2,PTGER1,TNFSF18,PPDPF,DNAJC8,RAB33A,CRYGD,RNF167,FAM107A,TNRC6C,SPTBN1,GNPNAT1,GIMAP2,EIF3J,FERMT2,TOMM40L,UTP23,CHI3L1,RNASEL,PLEKHJ1,MLF2,TIMP1,DERL2,TXNL1,IL6ST,TMEM59,RPL23A,LYNX1,EIF4B,SLC25A4,MRTO4,PTHLH,SMAD3,PPP2R1A,STK38,TIMM10,AP1AR,PCDH19,RAB5C,PNP,WEE2,SLC6A11,RAB37,FOLR1,CAV2,PSRC1,IFI35,FBXO25,CSTF2T,C1QL1,CRBN,CD226,SACM1L,VPS33A,B4GALT3,PDYN,ZFP1,BEND5,CMPK1,SNRPA,CTNNA1,RAB2A,WDR44,GPIHBP1,TRAPPC6B,CCNF,VAMP2,FN3KRP,WIF1,DYRK1B,PHYHIP,STAT6,ACADSB,SNX24,ISG15,INPP4A,KCNIP3,ARCN1,EZH2,FGFBP2,RAB9B,AMT,TMEM91,SLC43A2,ZCCHC9,TOP3B,TEX12,B3GNT2,HIGD2A,MRGPRX2,GRIA2,LRRC24,FLYWCH2,LIX1,KLK5,CAB39,DDX4,PCGF3,GPX5,GDE1,TMEM14A,CDH8,CPSF2,TAF5L,MYEF2,PNPLA8,GLT8D1,NGB,UQCR11,MOV10,AKIP1,SOS2,PIWIL2,PGM2L1,ROGDI,SLC23A2,GYS1,ELSPBP1,STX18,SLITRK2,FOXN2,RBFOX2,CDKN1A,GK2,PPFIA3,SDHAF2,MED11,CLIC2,RBMX2,NDE1,AMY2B,LDHAL6B,CCDC65,HMBS,CD2BP2,TDRD7,ACTL6B,FAM168A,LY6G5C,UBE2D1,SNIP1,SLC4A8,ABHD13,ZBTB45,HRH3,RAB1B,INHA,RGS5,RPAP2,EIF2B5,SH3GLB2,GALE,CXXC5,ENDOD1,CIRBP,UTS2R,NEK7,PHKG1,LASP1,SPOCK1,FUT8,WBP2,GTF2A1,CREBL2,TXNIP,AQP4,CCL25,GNMT,GLE1,ZSCAN1,EIF4EBP3,WDR37,IL23A,PSMD6,SLC39A9,FURIN,DHX9,LDHA,PFDN6,NUBP2,UBXN10,SLC20A2,PCDHA5,GSK3A,PRCC,NUDT19,RANGRF,ABCC5,THOC1,DNAL4,FATE1,ATP2C1,RC3H2,THRAP3,EEF2,GJA10,EFHC1,SLC25A32,XPO1,EXOC2,XPO5,INTS10,SURF4,TF,CREB3,RNF103,GPR162,APOBEC3C,RNF187,ZMYND11,SLC7A4,ZNF513,KIF1C,GAS8,CHRNA7,CDKL2,CD3G,BRMS1,NQO1,IPP,TBCE,SPATA2L,LMBR1L,IGFBP4,AKR1C2,NPVF,TAC1,RBM23,TMED1,ADAT1,HEXA,BRI3,TRMT6,PTCRA,CXCR1,NEDD8,HBB,FGF17,KCND2,CCL21,NDUFA5,ST13,RASGRP2,LPXN,IL34,DFFA,UCKL1,ACAA2,RAP1A,WWP2,RABAC1,TIGD7,FBXO30,CD2,POLR2I,EIF1AD,NAA11,ISYNA1,NDUFB8,APH1A,FRA10AC1,PDIA3,XPOT,WNT7A,LEPR,STX17,RPRML,MSX2,PELI3,CDC37L1,SNAI3,KRR1,NLE1,HSPE1,CLDN14,ZKSCAN1,STAMBPL1,SIPA1L1,PGBD2,SERPINH1,RPL37A,HADHA,LEAP2,DHX16,RAB4A,SOX21,TRA2B,NUDT16,GXYLT1,B4GALT6,HSPB1,KCNA2,LHFPL1,SYNGR1,ZMAT5,RTP4,LSM6,PRKX,FGF13,PROX1,ENPEP,NAB1,SLPI,USP39,CERK,ZNF174,USP38,DCAF5,ESR2,CDK6,CWF19L1,SNRPD2,ADCY3,SFTPD,CLEC12B,RAB8B,CTNNB1,CYP2D6,SOCS2,INTS12,RAP2B,ABHD16B,TNFAIP3,MMACHC,TRAF7,MTMR12,DUOXA2,SIRT7,FYTTD1,NOL4,IQSEC1,TAPBPL,ETV6,RRAGA,SPRED1,H19,TSSC4,MAK16,ALDH1L1,POLL,NONO,TCP11L1,SOST,HPCA,SV2B,OR2A2,EIF4EBP2,SIVA1,GFOD1,SNTA1,SNAPC1,NDUFAF2,GPR37L1,INPPL1,KIF2A,MIA2,BACH1,CCDC42,NPTN,FCAR,POU1F1,CYC1,PTDSS1,ID1,ENTPD4,ARMC8,SLC35A2,DEGS1,CRYBA2,SCAMP2,SPEF1,SLC5A6,PRKD3,CYP4F8,NLGN2,DEK,PPIB,BPGM,CDKN3,CD164,AKR1A1,NOP58,SPATS2L,NFE2L1,RBCK1,MRPS25,CTSD,PGAP2,MRGPRX4,FABP5,PWP2,RAB3C,MTAP,CTSK,CACYBP,URM1,CETN3,NFYA,S100A10,FAM200A,STX8,TGFB1I1,DUSP1,TOLLIP,BATF,ANP32B,CHST9,CPT2,AP1G2,NDNF,LCN6,SETD4,RPGRIP1L,OR2W1,CCND1,WFDC13,ACOT13,TMED3,FBXO9,COX7A1,AP3S2,TMEM33,MRPL47,S100PBP,MPHOSPH10,KLF10,FAF2,BMPR1A,SPINK13,RHCG,ARHGAP21,SCG2,ATP6V0B,TMEM219,EDF1,ZNF207,POLR3H,C1QC,TRIM3,TMUB1,SLC17A5,ZNF671,SLC25A31,UGCG,MEAF6,LYPLA1,RPS14,LIG3,KLHDC8B,RNF141,DOK4,ARHGAP1,PLA2G5,KLK9,PDIA6,SDR42E1,UBR7,CD99L2,PRIM2,SNRNP27,TRIM32,E2F6,ZMPSTE24,EXOSC1,EFCAB7,GPR89A,MRPL23,GDI2,GFM2,GSTO1,TMEM156,GALNT1,SOCS5,AK2,PSMA3,CCDC69,MRPL13,EHBP1,MDM2,MGP,LYAR,GNRHR2,TOM1L2,EXOC8,PFDN5,UST,RND3,CNP,NUDT3,B9D1,CRABP2,DPP10,PRRC2A,SF3B4,IL20RB,DKK3,CCNI,PPIL4,RAB11A,CDO1,L1CAM,WDR38,FIBIN,SNX20,TLR9,COMTD1,FNDC8,APEH,FGD2,DLX1,AKT1,SENP5,IDH3B,CYP11B1,GRM2,CTNNBL1,TLR3,GPAA1,JAKMIP1,CYP39A1,HSD11B1,MYL12A,SWAP70,FAM8A1,EIF4H,ITK,NCR3,CHDH,GNRH2,ENY2,RAG1,IMMP2L,MEF2A,DHRS4,SLC35A1,MRPL24,MRPL50,ZNF304,SNAPIN,SLC30A5,KLK3,IL15RA,SLC38A9,RMND1,MIOS,FAM78A,PPP1R2,CCT2,ATP6V0E1,UBE2D3,UBE2A,ARMCX1,IRF1,STRBP,ING1,TRIM23,NAIF1,NHP2,LTBR,GAL3ST1,CASK,FGFR1OP2,GABARAP,PRPSAP1,ELMO1,GRPEL1,TCP11L2,GLUL,CNIH4,CDK5R1,NRP1,NCKAP1,KIAA0232,ATPAF2,CLU,LMO4,SLAMF9,ZMYND19,TAAR1,CCR6,ID4,SEC14L1,ZNF319,APOBEC3A,ZNF397,XAGE5,RARRES2,KPNA1,PIWIL4,CSNK2A1,GSTO2,KBTBD2,ATF4,CTNNBIP1,GNG7,JOSD1,SUPT7L,RS1,KIT,LSM3,AFTPH,S100A6,DYNC1I2,CYP27A1,ZYX,UBAP1,CDC73,LHX2,MMP9,BTF3,SNAP91,MYH2,SLC7A9,HEBP1,ALKBH4,PGK1,VRK1,ROPN1B,TMIGD1,DNAJC5,FZD4,MEST,MTPN,WDR77,ATP6V1G1,LYG2,MFSD6L,GPBP1L1,MX2,SYN3,ZCCHC10,AAMP,FBXO42,TMEM215,ZNF24,TSEN54,SERPINB10,FGF1,AZGP1,INO80C,HBE1,ABCB1,PSME2,AZIN1,CCL19,TBC1D10C,MAGOH,NKX3-2,MLF1,GTF2E2,LBH,JAK1,NDST1,TNFAIP8L2,DEFB116,DHRS3,CDCA3,RAB3B,SMAP2,KTI12,NFIL3,ZBTB38,TRIM37,HECW1,PTPN1,SETD5,HNRNPC,RMND5B,RBBP7,SLC25A21,PGS1,ACTA2,TRIM21,SIX5,ARMCX2,SPR,GALNT12,ARFIP1,PPARG,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,HEY2,PCDHB8,RBM17,FAM199X,RABL2B,NIPA2,CLDN11,TRAPPC1,SLC35E3,SPTAN1,RNASET2,NPY2R,LRP12,CIB3,TACR3,PRMT2,CAMK2G,TMX4,BUD31,SRP54,CCDC47,TTC4,SCFD1,GHITM,CACNB4,TUBG1,RPL15,HCRT,CAMK2N1,FGFR1,SHC1,PYGM,CCDC127,PEX3,FAM89B,RCVRN,PPP3CA,CRYGB,KCNJ11,CD200R1,CCT5,ENPP4,MCOLN1,PSMB5,SORD,SBK2,AGK,FBXO32,ANAPC2,ZNF593,ARMCX5,PRPF4,IMPACT,CD58,AGER,IDH2,FKBP14,RAB18,API5,RPL9,TST,DGCR8,RNF5,FKBP1A,SRXN1,DNAJC30,EHD3,ST3GAL4,MRPS18B,ZMAT2,NT5C2,DOLK,CRYM,SAMHD1,TPH2,SPRYD4,KCNS1,PYGB,TRIM6,HOMER1,PDE8A,PSMB9,FOXP1,SLC4A10,SAMM50,KCNJ8,ENC1,LAP3,ADIPOR2,C2CD2,EFHD1,EXTL2,RCCD1,ALPL,SLC20A1,HNRNPH2,HMOX2,NPTX1,CLIC4,COX11,IZUMO4,AHCYL1,ALDH1A3,ADM2,C2CD4C,TTC33,RPL39,BRD3,SURF6,FAR2,TMEM108,DVL2,TESK1,TFPI,PRKCA,KLHL26,BET1L,MMD,WRAP53,GAS2,UCHL3,TRAPPC4,EEF1A1,MRPL53,NLRP2,HDAC3,RPL29,GLRA2,MAP1S,BHLHE40,PI16,LRRC4B,TOMM40,GREM1,COX4I1,FABP4,MPHOSPH6,ANAPC4,GDPD3,ARPP19,ACVR1B,FAH,CTDSP2,RPL10A,SDC2,CARHSP1,KLHL9,TIMM8A,NPC1L1,DNAJB4,TXNRD2,C2CD2L,RAD21,RAP1B,AIFM1,SNX14,COQ10B,POLR2G,ACTR1A,FITM1,LAT2,MAD2L2,TMPO,UBTD1,COX6A2,POLR3GL,RBBP4,FAS,ATF1,ABCB9,CUL3,COX16,ARMCX3,RBP5,DNAJC4,EIF3D,ERVFRD-1,AKT3,MAN1A2,POLD4,CCDC92,SKA1,GRB10,ELOVL4,CHMP2B,ZNF704,PTPMT1,KBTBD6,FARSA,UBE2H,CD86,PNMA5,MANBAL,PSENEN,SLC2A8,ENO2,CCL27,ZC3H11A,HTR1A,TMX2,SFRP1,ELF1,WSCD1,GOSR2,SLCO1B3,FGF23,CYP2R1,SLC25A39,PRR5L,CD14,G6PC3,RANBP6,RNASE6,DPM2,TP53I3,RPS26,RNF40,DDX1,KDELR2,DAP,KLHL3,CFL1,BRIX1,IRGQ,S1PR4,TNFAIP1,FAM169A,TMEM11,CRADD,PPP1R3C,KCNAB1,AGTRAP,SEMA5A,MCMBP,APBB3,LAMP3,MATR3,CHPF,REEP6,CNOT6,PPY,CRYAB,ROMO1,GNL1,ZNF473,SELL,KIAA1143,ATP1B3,DNAJC2,GNB1L,WDR82,TLR10,ZBTB25,CD28,NAB2,FXYD6,CYTH2,RNF11,SYNGR2,APOC4,TAF7,FTH1,SNX1,PSEN2,SLC35F1,ALB,CCM2,PIWIL3,IL2RG,TNFAIP8L3,SLC48A1,CDC42,BACE1,DUSP10,SLC38A1,VPS16,ACO2,CLN8,SLC25A26,SYK,CPSF4,LCN8,AGA,CD63,AGR2,CACNB3,PCBD1,TTC23,NLGN1,MORF4L1,TMEM174,PSMA6,PCSK9,KBTBD3,AKAP1,CLEC1A,DNAJC24,SLC6A3,CASC3,CNKSR3,TCF21,CALML5,VAPB,PNMA1,SP2,HEBP2,PSMG3,GPR173,TOP2B,GEMIN8,MYL6,TIRAP,RPS9,SEC23A,TUSC2,MKLN1,CCL28,SHISA2,RAB35,MAB21L1,KCTD10,PPP1R8,TMEM50A,SMG8,LILRB4,MYC,CD40LG,SEC11A,FEM1A,VPS26A,CMTM6,EEF1E1,ZBED3,DAG1,DUSP6,MTHFS,PPIF,SETD7,TXN,MAF1,RPS12,CYB5D2,TAX1BP3,ZNF790,RDH12,CALY,TNFSF12,GABPB1,SCGB1C1,ARF4,SERTAD3,MT3,EIF1B,GABARAPL2,PML,DNASE1L1,PSMA4,PKIA,TRAFD1,TRIM35,PPM1B,SENP8,STX7,MGST2,GADD45B,HBA1,NECAP1,GPC4,MZT2B,LIMS2,PRDX6,AP2M1,TAX1BP1,KIN,TP53,NFKBIL1,CRELD1,INMT,PTRHD1,TOX,IRF8,RWDD4,KPNA6,CYB561,BET1,FCER1G,SLC25A46,HEXIM2,TMED4,TBC1D17,HSD17B1,TSEN34,FTSJ3,GSTM3,SYNDIG1,IL12A,RHAG,TLR1,CAPG,SAR1B,CHORDC1,ZBTB16,ANAPC16,BRMS1L,HCST,FBXO34,DHRS1,WDR55,RALA,FTHL17,F11R,ADK,G6PD,EXOC5,SYBU,SERPINB6,NAA15,PTGES,ACADS,RNF128,PPP2R5A,VASH1,TLR7,GAPT,SERPIND1,CHST7,CRYL1,RPL24,ENO1,GNPTG,RASL11A,TBC1D19,CLSTN3,RGS6,CSTA,ELOVL6,ALOX5AP,TFPT,ZNHIT1,MECP2,PRDX4,SLC25A14,POP7,STYK1,RNF181,DCAF4L2,RPRD1B,SNRPN,TSPO,LYPLA2,PHF21A,COX5A,SLC1A2,THNSL1,RHBDL3,TRMT61A,CAMP,GPD2,CELA3B,FBXL7,LBR,CYP11B2,RAB3A,DDIT4,SMYD3,FAM91A1,LCN12,CTNND1,NMBR,LGALS3,MAP4,HHIP,LUC7L3,YIF1A,CA8,CHN2,TMEM60,HBEGF,CALU,AIF1,HAX1,LRRC20,EGR2,RPS3,FOXJ3,RAD23B,USP30,UFM1,KCTD11,GPR146,CLEC7A,APPBP2,ARPC2,ZHX3,IL7,NECAP2,SRSF4,SH3BGRL,EXOSC3,PID1,MYL12B,GINS3,FGF3,DRG1,CEP85,ERLEC1,SRPRB,NDP,TMEM42,SNX33,MED23,USP13,SDCBP,CNTFR,KRT222,PDP2,NEURL2,SMNDC1,POLR2D,SNX12,WNT10B,DGCR6L,FBXO11,RBBP9,SPSB1,NTNG2,LRRC8D,ETFB,VIP,MIF,RBM15B,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,ZNF451,GNRH1,WDSUB1,ELK3,DPH3,CRISP1,LRRC40,CD81,MT1E,UBE2E2,FSTL1,HGS,RHOBTB3,POLR2L,POLDIP3,COMMD9,STK3,CBLN1,HSPB2,TNKS2,LILRA2,LY6H,PLSCR1,PTP4A3,DCAF12L2,CREBZF,MRPS18C,NT5DC1,TRIM36,PROK1,JAK2,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,DDAH1,GPR35,HFE,NDUFA1,ALG11,TRIM29,CORO6,RB1,DPH5,PNMA3,RGL2,ITGB5,TRIM34,NDUFC2,TMEM205,NINJ1,ICOS,B4GALT4,CAV1,LXN,TCEAL8,YIPF3,RPS2,TTPAL,PMAIP1,CCIN,UBE2L3,EIF3G,MEPCE,SPEM1,CYP3A43,PDE4B,AKR1C1,MRPS11,RAB39B,CSNK1G3,CPLX2,PRND,ABHD10,HUWE1,SREK1IP1,CNTROB,FTSJ1,LSM14A,CAPN2,SLC8A1,ICAM2,ABHD8,YWHAZ,STARD3NL,TM4SF18,TNR,BOK,GJA1,MAGED2,SURF2,SLC29A1,AASDHPPT,RNF222,REEP4,TM4SF20,CCNA2,HOMER3,CXCR3,MAGEB10,GRM1,PCGF6,KCNJ10,SHPRH,SPATA2,ADORA1,SLCO3A1,TAF1D,EHD4,ZNF511,CEND1,FAM81A,SLC25A1,HNRNPF,STAMBP,EPHA4,CTU1,KCNJ2,ARL4D,TXNDC17,LIAS,CITED1,CPLX3,TNNI3K,NPY1R,GCLC,PSMD10,DMTF1,PLG,DLK2,CDK12,PSMB7,TNFAIP6,FBXW7,ARL2BP,ING2,FRZB,SPP1,TSR2,CHRM3,PLCB1,GPR17,GPC1,PRSS23,ZNHIT6,PYCR2,ZNF428,PDE2A,CDIPT,TNFSF8,SIN3A,CDK7,PLAC1,PSMD7,SCAND1,CTTNBP2,RGN,RAB6A,TNFSF15,SLC6A2,CD40,AIP,CRY1,MED22,ARFGEF1,NOG,TLR8,PMPCA,TRAF3IP3,PIWIL1,RGP1,CCDC90B,SRPK2,TAB2,LDB2,YPEL4,GADD45G,RPA2,TMEM107,DCTPP1,OR4A47,THAP1,FBXL4,CD34,CPXM1,PRCP,EID2B,SPINK9,SLC25A24,GLCE,GK5,SSNA1,STAR,TRIP4,RPL10,PDCL,SUPT5H,FBXW4,TAS2R7,ST3GAL2,CD209,IL2RB,PTGFR,IP6K1,ZDHHC16,TEX261,PPP1R11,MDFI,MSH6,RAP2A,APLNR,CYP4V2,SRI,NCAPG2,CNPY3,DTWD2,PSMD3,POLR1D,GPR160,RNF10,GP9,POLE3,CCDC3,VAV2,BTG2,ITGB8,TMEM229B,HINFP,CMC1,NUFIP2,GNB3,TRIM44,NR1I3,LRP10,TICAM2,FAM20B,FHL3,PPWD1,PQBP1,GPRASP2,CRYBA1,MPV17L2,THAP8,WDR45,NRM,HSPA5,GNA11,SERTAD2,HSPB6,HSPD1,EIF1AX,RNASEH2C,PNPLA4,TMEM115,NPC2,PARD6A,LRRC28,TCEA2,SAP18,EXOC3,TMEM81,CAP2,SLC22A6,SPG21,TIA1,DDR1,RBMS2,TGFB2,VPS54,SLC25A27,ZNF622,ATG9A,S100A11,THOC3,PIGA,GLOD4,BOLL,MX1,DPEP3,TMEM183A,BTG3,RUSC2,CD9,GRPR,GADD45A,IGFBP3,GORASP2,THUMPD1,TTC9C,GMPS,PELO,IGF1,CCR7,SNAP25,RXRG,RRAGB,SNRPE,GRIK1,CMA1,DLGAP4,ANXA4,IL18BP,RASL12,GALNT2,RDH11,PIH1D1,KCTD3,HAUS2,GALC,RP9,ELFN2,LRRC8A,SSPN,CNPY1,GNGT2,LBX1,NKAP,MBD3,CDC23,DMPK,BRAP,TANK,SYNGR3,MPG,PRR13,SLC25A5,WSB1,LYZ,TOPORS,MACROD1,ZNF518B,CYBRD1,ADCK1,FAM151B,FAM136A,SLC35E4,TMEM165,KLHL25,RPE,SULT1B1,SLU7,VEZT,FAM3C,PTP4A2,MFAP3L,IRF7,KLRC2,TOX4,CPNE2,TMBIM1,CYTH4,IFT172,RAMP3,NUCKS1,IER3,CENPL,SGIP1,MRPS17,MECR,MRPL9,UBE2G2,FEM1B,FXN,SUPT3H,UPRT,TBCCD1,TRAF6,VPS72,KRIT1,ROCK2,KCND3,FUBP3,GIN1,TKTL1,RPL18,SPRY1,RPS10,CLDND1,CCDC106,ETNK2,IMPA2,TADA3,TRAM1,TMEM196,FUNDC1,AP1M1,ECHDC1,UBA52,MGMT,TRAPPC6A,MDC1,MTCH2,ITM2B,SP1,LMO2,FKBP1B,LCORL,EDA2R,PSEN1,MAGEC2,RASSF8,CLEC6A,KCTD17,SSBP4,RBP2,TLCD1,AQP11,SRFBP1,EIF5B,ARHGAP12,PFKFB2,MREG,ACER3,DIRAS2,YTHDF2,FAM161A,ANKRD6,PDE12,NAA16,GJC1,SLC12A2,RUNX1,RPS20,SCML1,ZFAND6,TAPT1,MED10,TYMS,ZNF581,SUCLG2,DUSP3,PDE7A,CIAO1,ATP8A1,KIF3C,VPS18,GHRL |
| 8.274e-24 | -53.15 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 14773 | 4431 | 16828 | 4835 |
SART3,PTPRZ1,IFI16,VPS39,MYLIP,FAM174A,SUPT4H1,ATG3,INA,CFTR,CLPX,CLP1,VWF,CDKN2D,GPR37,ESD,ATP6V1D,ART5,TMEM39A,PSMB10,CDK17,PITPNA,RAB32,CRYBA4,CRYZ,FOXC2,BLVRA,APOBEC3B,PCBP4,MLH3,HS3ST1,TULP3,BMPR1B,SRM,MED27,RANBP10,ADH1B,PSMD1,BARX2,MPP1,COPE,RBM41,RWDD1,SLC25A3,HCFC2,DCTN3,LSM5,IRF2BPL,PRKCB,RGL1,SUV39H1,RPL4,HBP1,DYNLRB2,CKS1B,DIRAS3,TP53TG5,SIGLEC5,HDAC11,ATG16L1,TTLL10,CHCHD2,SKP1,GJB1,GCHFR,CSF2,PCYT1B,KRT8,PRELP,LCP1,AGGF1,HNRNPH3,ZNF200,IZUMO2,TPST1,PGAP3,MB21D2,LCN15,SLC39A10,MCCD1,HM13,VCPIP1,JUNB,ALCAM,SNRPD1,CCL24,LIPA,UFSP1,PTPN5,RNF182,SMAD9,RELL1,TIMM17A,CYP4F22,PIGC,ARFGAP1,STK38L,MVD,CDC26,SHC3,PREP,SRP72,SLITRK1,DDIT3,EDEM2,FIS1,RPL28,HCFC1R1,CACNB2,LYPLAL1,HSDL2,DYNLL1,RNF139,SMG5,PLP2,DUS4L,ABCF1,ADRB3,FMOD,SPATA4,CMTM7,TBC1D16,CA12,SLC7A1,IRF4,CSRP1,LEMD3,STX5,ARL6,RAB11B,CCND3,MARCKSL1,SLA2,IFNAR1,SDR16C5,TNPO2,THOC6,PYCR1,HINT1,RXFP2,RAB9A,RPAP3,CCL11,SPCS1,TDP1,MID1IP1,GLIPR2,SNRNP70,SERINC1,PLEKHF2,DICER1,SLC6A7,MAGEB1,POU5F1,FGF16,MSN,HBM,ZNF362,SLITRK5,SAP30,RNASE4,DDIT4L,IL21,RPL19,ARL11,FHIT,MAP3K3,RNF7,TECR,MRPL16,EZH1,ARGLU1,PNRC1,LAMTOR2,SLC41A1,MFAP1,MXD1,UBE2I,TMEM106B,UCP2,MED29,DOK5,DCTN4,SEC22A,MAP2K3,CXXC1,RPL7A,LSM12,FIG4,RCHY1,SPHK2,MRPL12,FGR,PPT1,B3GALT2,ARF6,ZDHHC24,TNIK,S100B,LRFN3,PDZK1IP1,OR5K1,PDE6D,UBE3A,SMARCE1,PITHD1,SH3BP4,LEP,ZC3H14,CBFB,ASPM,EFNA5,ZC4H2,CETN2,TADA1,CACNG3,RIT2,ZHX1,SERTAD1,KCNIP2,FA2H,ERRFI1,HNMT,CTSA,DPAGT1,ZCCHC7,PHTF2,PPIL3,LPCAT3,GPR83,BTBD10,EMILIN1,PDCD5,PRDX3,ZBTB26,LRRC14,TUBA1B,CKB,THAP6,PHF7,MRPS26,HMGB1,GNG11,ARF1,ZMYM6,EIF2B2,SEC61A1,TTR,GAD2,METTL18,RSBN1L,BGLAP,COX7B,CDC42SE1,FAM83A,NOL12,RHOG,RGS1,SDHC,ASB11,KIAA1958,EID2,ZNF345,FBLN5,LYRM2,FOXD3,MAEA,CXCL10,CDH7,ASCC1,SMUG1,SVIP,DUSP18,UBXN2B,ZNF770,TPD52L1,CDKN1B,CMBL,SCHIP1,TAF9,MEA1,PHOSPHO2,RFX5,TMEM198,TRAPPC2L,NMRAL1,MAT2A,CD200,ST8SIA4,TMEM220,TMEM168,NCK1,SIAH1,STRADB,LRP3,AHSA1,PLEKHF1,ZBTB6,KCTD16,SLC15A1,HNRNPAB,GPR78,ZNF655,TRIM62,TEX19,CLK1,SKAP2,RASSF4,KCTD20,SERPINA3,RSL24D1,TRAF1,ZMAT3,BRS3,C9orf72,NAA30,NETO1,CDR2,PTGER2,LSM4,IRF9,HSD17B8,DDX39B,CGRRF1,PSMB4,HERC3,DOK6,SEMA3C,LRRN4CL,GDAP1L1,SSBP2,PDCD10,RPL31,WTAP,ZSWIM7,TSPAN3,BAD,MGST3,PRPS1,HAS3,CRHR1,AKR1E2,UQCRC1,NOC4L,ANKRD46,CEP70,ABHD2,ARL6IP5,CTDSPL2,SNRPA1,PSMG2,DTL,TNFAIP8,KDM1A,NDFIP1,CCDC22,TBCEL,FKBP2,PRSS35,UNC45A,ISG20,TMEM87A,NUDT1,RALB,CYP26A1,GMNN,ESYT1,F2,ARL5B,ANKH,VPS26B,YKT6,AANAT,HAPLN2,SAP30BP,EDC3,GMDS,WNT2,LDB1,TRAPPC3,NRGN,CSRNP3,MFSD3,BIRC5,RANBP1,ATF3,CTLA4,RBM5,MAP1LC3B,PRSS37,PDLIM3,ACSS2,DEFB1,IFRD1,RHOU,DLG3,CEBPE,RPL22,TMEM176B,RPLP1,SNX11,TIMMDC1,SERPINB9,MT1X,UBE2V1,PDE6A,IMP4,TRNP1,HELT,SSH3,HOXB8,SEC61G,CENPM,EMX2,GFM1,ADIPOR1,GAL3ST4,PRM1,POPDC3,RETSAT,SLC7A11,MET,FZD6,SETD3,GPR75,TMEM126A,ACP2,GNPAT,FOSL2,ACTL6A,EGR1,DIO2,ZNF436,WBP11,STARD7,ZNF343,CHTOP,SYPL1,CORO1C,RACGAP1,RRP7A,CCDC126,RBM3,STT3A,MAGEA4,RPSA,PIK3CG,NPBWR1,ERLIN2,HYAL2,UBE2S,ARHGAP15,RHOH,SEMA7A,NAP1L5,ZCRB1,MED4,CYB5B,APOC2,TRMT5,BCKDK,LIPT2,HPCAL1,MRGPRX1,TBC1D1,GPR34,TIMM13,RPF2,XBP1,THG1L,PDLIM4,GABBR1,ERCC3,CEP57L1,TACR1,ARHGAP19,DIS3L,CA14,MTA3,DRD3,EMILIN3,CEACAM5,NAP1L3,NACC2,CHRM5,DCAF16,CLRN2,SRD5A3,C1QL2,PLCXD3,REG1A,DNM2,GTF3C4,MMP20,HTR2A,SMARCB1,ACTR1B,STAP1,SUGP1,FMO1,STARD5,ABCC2,ALG5,SDHAF1,AQP3,ETFA,PRELID1,ECD,CD59,ITPRIPL2,GAB1,AKT2,PRSS1,APEX1,PSMC5,SOX9,KCNG3,CHST10,GPM6A,PNPO,COTL1,TLR5,RFC4,LCN1,HS3ST3A1,TICAM1,MLN,KLF12,IAH1,WDR12,PDCD1LG2,GLO1,RAB1A,NEU1,VSTM4,AMELX,CNOT8,PIGK,PELI1,FBXO31,VSTM2L,MAP1B,SCN2B,ANKRD10,TEF,TCTA,PCP2,SOD2,ADD2,IMPA2,TMEM196,AP1M1,ECHDC1,FUNDC1,UBA52,TRAM1,TADA3,MGMT,ITM2B,MTCH2,SP1,TRAPPC6A,MDC1,VPS72,KRIT1,ROCK2,KCND3,FUBP3,TBCCD1,TRAF6,RPL18,GIN1,TKTL1,CLDND1,CCDC106,ETNK2,SPRY1,RPS10,GJC1,RPS20,RUNX1,SLC12A2,NAA16,ZFAND6,TAPT1,MED10,TYMS,SCML1,PDE7A,SUCLG2,DUSP3,ZNF581,GHRL,VPS18,CIAO1,ATP8A1,KIF3C,PSEN1,MAGEC2,FKBP1B,LMO2,LCORL,EDA2R,RBP2,AQP11,TLCD1,RASSF8,CLEC6A,KCTD17,SSBP4,MREG,ACER3,DIRAS2,SRFBP1,PFKFB2,EIF5B,ARHGAP12,FAM161A,ANKRD6,PDE12,YTHDF2,PIH1D1,KCTD3,RDH11,NKAP,LBX1,HAUS2,ELFN2,RP9,GALC,LRRC8A,CNPY1,SSPN,GNGT2,MBD3,CDC23,DMPK,MPG,BRAP,TANK,SYNGR3,TTC9C,PELO,GMPS,GORASP2,THUMPD1,SNAP25,RXRG,IGF1,CCR7,GRIK1,DLGAP4,CMA1,RRAGB,SNRPE,GALNT2,ANXA4,IL18BP,RASL12,TMBIM1,CPNE2,CYTH4,IFT172,RAMP3,KLRC2,TOX4,CENPL,NUCKS1,IER3,UBE2G2,MRPL9,FEM1B,SGIP1,MRPS17,MECR,FXN,SUPT3H,UPRT,WSB1,LYZ,TOPORS,PRR13,SLC25A5,FAM136A,SLC35E4,MACROD1,CYBRD1,ZNF518B,ADCK1,FAM151B,RPE,SULT1B1,TMEM165,KLHL25,IRF7,SLU7,VEZT,PTP4A2,FAM3C,MFAP3L,FHL3,TICAM2,FAM20B,PQBP1,GPRASP2,PPWD1,NRM,CRYBA1,MPV17L2,THAP8,WDR45,HSPB6,HSPA5,GNA11,SERTAD2,BTG2,ITGB8,CCDC3,VAV2,HINFP,CMC1,NUFIP2,GNB3,TMEM229B,TRIM44,LRP10,NR1I3,ATG9A,ZNF622,S100A11,TGFB2,RBMS2,VPS54,SLC25A27,GLOD4,PIGA,MX1,BOLL,THOC3,BTG3,TMEM183A,DPEP3,GRPR,GADD45A,IGFBP3,RUSC2,CD9,EIF1AX,HSPD1,RNASEH2C,PARD6A,LRRC28,TCEA2,PNPLA4,NPC2,TMEM115,CAP2,EXOC3,SAP18,TMEM81,DDR1,SLC22A6,SPG21,TIA1,SRPK2,TAB2,PIWIL1,TRAF3IP3,RGP1,CCDC90B,RPA2,TMEM107,LDB2,YPEL4,GADD45G,DCTPP1,OR4A47,PRCP,EID2B,THAP1,FBXL4,CD34,CPXM1,PYCR2,PDE2A,ZNF428,CDIPT,TNFSF8,CTTNBP2,RGN,RAB6A,SIN3A,CDK7,PLAC1,SCAND1,PSMD7,CRY1,TNFSF15,SLC6A2,CD40,AIP,TLR8,PMPCA,MED22,ARFGEF1,NOG,ZDHHC16,TEX261,MSH6,RAP2A,PPP1R11,MDFI,DTWD2,PSMD3,POLR1D,GPR160,APLNR,CYP4V2,NCAPG2,SRI,CNPY3,GP9,POLE3,RNF10,GLCE,GK5,SSNA1,SLC25A24,SPINK9,PDCL,SUPT5H,STAR,TRIP4,RPL10,TAS2R7,ST3GAL2,CD209,FBXW4,PTGFR,IL2RB,IP6K1,CXCR3,MAGEB10,HOMER3,SHPRH,KCNJ10,SLCO3A1,ADORA1,SPATA2,TAF1D,GRM1,PCGF6,FAM81A,ZNF511,EHD4,CEND1,HNRNPF,STAMBP,SLC25A1,ICAM2,ABHD8,YWHAZ,STARD3NL,LSM14A,CAPN2,SLC8A1,BOK,TM4SF18,TNR,SURF2,SLC29A1,GJA1,MAGED2,TM4SF20,CCNA2,AASDHPPT,RNF222,REEP4,ING2,ARL2BP,TSR2,CHRM3,FRZB,SPP1,PRSS23,PLCB1,GPR17,GPC1,ZNHIT6,KCNJ2,EPHA4,CTU1,TNNI3K,CPLX3,NPY1R,GCLC,PSMD10,ARL4D,LIAS,TXNDC17,CITED1,DLK2,CDK12,DMTF1,PLG,TNFAIP6,FBXW7,PSMB7,HCAR1,GSTA2,TMEM127,FAM53C,MCL1,ALG11,GPR35,DDAH1,HFE,NDUFA1,DPH5,PNMA3,TRIM29,CORO6,RB1,TNKS2,LILRA2,LY6H,COMMD9,STK3,CBLN1,HSPB2,PLSCR1,PTP4A3,DCAF12L2,CREBZF,PROK1,JAK2,NT5DC1,MRPS18C,TRIM36,EIF3G,MEPCE,TTPAL,PMAIP1,CCIN,UBE2L3,PDE4B,CYP3A43,SPEM1,MRPS11,CSNK1G3,RAB39B,AKR1C1,SREK1IP1,CNTROB,FTSJ1,CPLX2,PRND,ABHD10,HUWE1,TRIM34,NDUFC2,TMEM205,ITGB5,RGL2,NINJ1,ICOS,B4GALT4,CAV1,RPS2,TCEAL8,LXN,YIPF3,SGMS1,MGAT4A,RBBP8,DUSP21,TRIM45,ATAD1,MRPS34,IGSF11,CYP2C9,CDC7,PRL,MPPED2,NDST3,FBXO8,SLC19A3,WDR11,NHEJ1,FHOD3,SLC35B3,TYROBP,TBC1D25,AIPL1,PEX13,TNFAIP8L1,VMAC,NBN,SEC13,IL2,ZDHHC4,WDR5B,CDC20,SNRPG,TIMP4,ACCS,XRCC5,TAS2R13,DBR1,TSPAN17,PRKRA,ZNF451,PRKCE,WDSUB1,GNRH1,COX6B2,TMEM170A,RNF133,CRISP1,LRRC40,DPH3,ELK3,CD81,MT1E,FSTL1,RHOBTB3,HGS,POLR2L,POLDIP3,UBE2E2,PPAT,IL17F,NUDT9,CYGB,GGH,TNF,KLF3,CCR4,CHRAC1,TFB1M,LZTFL1,SNRPB2,CGGBP1,RPL26L1,PHF13,ABHD12,BANF1,PARP2,NF2,KLHL1,FOXA3,CARTPT,SESTD1,AKR1B1,ADORA3,APEX2,TAB1,SF3B1,LY96,AP1S2,MAD2L1BP,TMEM47,ANKMY2,CPT1B,RBM27,ZBTB39,CNN3,JAKMIP2,CDH11,PSMC3,IVNS1ABP,PIK3CA,SNRNP40,FAM83B,NDUFS2,TMEM185A,BAX,PEBP4,GH1,ATP1A3,PSD2,NUDT2,TMEM38B,TSPAN15,NPM3,CRTC2,GSTM4,VTA1,RPIA,PIK3AP1,COX6C,PICALM,LST1,XAF1,COCH,FEM1C,MIS12,TMEM89,GABRA1,PRNP,CAND1,HSD17B10,BCL9,ASPA,TRPC1,LYPD6,ELMO2,GTPBP8,HS2ST1,DR1,CBX3,GTF2F1,DLST,E4F1,TMED9,GSTCD,BCL6,SSX2IP,TPPP3,ZNF263,MTDH,USP6NL,SGTA,CA2,SNX10,MAX,TMUB2,RHOB,NRSN1,HOXB1,YIPF4,CSNK2B,MRPS18A,C1QL3,VMO1,TRIM11,GLRA1,G2E3,QPCTL,RBM18,TOPBP1,MTG1,RPL3,MRPL52,MYD88,FCF1,CD1D,E2F4,TMEM209,GFI1,GLYAT,FLRT2,BOLA3,DEDD,PPM1G,CDC42EP2,CBX5,MYCT1,ARL10,FAM118B,TM9SF1,COMMD2,MAGOHB,PEX5L,CDC123,UCK1,GNAI2,GABARAPL1,CD46,KCNMB1,TRMT1L,GSTK1,NAE1,KCNMB2,GTPBP1,RPS11,TNFRSF14,TXNRD1,TMOD1,KATNAL1,AZI2,EGFL8,ARL15,ILVBL,NDUFA12,NUDT5,DNAJC25,CRKL,TGIF2LX,ATP1A1,AOX1,PSMA5,B4GALT1,STARD13,ZFAND2B,DNAJB6,GCC1,LRRN1,CD1B,DNAJC27,KDSR,RP2,CENPP,STX12,GZMK,TMEM199,FBP1,NLRP1,CNPPD1,RAF1,IRF6,DNAJC10,RGMA,PRRG1,SAT2,GPNMB,RNF14,GTF3C3,KLHL7,MCHR2,ZNF330,DET1,CSTB,RPL10L,COG1,SCYL2,PHKA1,ALG2,MBLAC2,UBN1,TPSG1,FOXP2,CYP17A1,UBE2F,CCHCR1,RPS5,SNAPC2,SLC22A12,CYTH1,PDE9A,SLC1A1,CCDC71,DDX5,EIF4A3,LAMTOR1,ADNP,RAP2C,RPS27L,SEC61A2,ELAVL4,GOLPH3L,TNNT2,STK11,COMT,TESK2,GPSM3,TP53INP2,SNRPD3,LAMTOR3,ZNF175,RIMKLA,EXOC1,GPX4,SEC62,FGF12,PHAX,BAALC,FKBP10,LY6G6C,RHCE,ANGPTL2,DOHH,FUT1,PLAA,BAP1,IL1B,GPR26,SYS1,ARFGAP3,ARL4A,LITAF,LRRC4,MEF2C,DRAP1,MSX1,CHRM1,IL3,DLG1,P2RY11,CD151,RPN1,KCTD9,TLR6,STAT1,ZNF507,PAX6,LMO3,EIF2S1,UGP2,LMBRD2,MRPS33,DPP4,PRDX2,HEXIM1,PC,RAB5A,APOBEC3D,NDUFB7,NEK2,NDUFV2,ZNF526,SSBP1,F10,KCNA3,TMEM31,PTN,ZBED4,DYNLT3,SP4,SDC4,CD79B,WASL,GOLGA7,TMCC1,REP15,BVES,RAB14,ZC3H15,SLC25A23,DSN1,SFTPC,YIPF5,TOB2,SLC6A4,PDSS2,NME4,FNTB,PATE2,GNG3,CDK5,MRPL51,RAB13,MAP1LC3A,RNF26,NDC80,RPP21,SNAPC5,PLAC8,CYB5R3,THBS3,SNAI2,TRUB1,CALR,DRG2,MAMDC2,TSG101,ADCY2,PKIG,MOBP,CYTL1,NDUFA4,SLC45A3,HEXB,SYNGR4,PPFIBP1,SHMT1,YWHAB,THY1,TESC,ZNF692,SLC25A44,CDSN,SESN3,BMP1,NR1H2,PRPF31,PHB2,TTC1,MMADHC,SPOPL,SYT2,TMEM95,LEPROTL1,ST6GALNAC3,TBC1D24,EDNRA,DAPK1,PDE1A,LILRA1,TPBG,KCNQ5,STXBP6,ARRDC3,ZCCHC12,LRWD1,SLC25A17,NFYB,STOML2,MICB,TOR1AIP2,RNF20,GPR15,COPS7A,PPARA,ACTL9,GTF2A2,ATL1,TPT1,SNCB,RRAS2,RPL35,POLR3F,FRS3,RERG,CHMP5,ASB3,AGPAT1,ZMYM4,EIF2S2,BTG1,CISH,CXCR6,GNA14,USP14,TSC22D3,NANP,TXNL4A,EYA3,DUSP26,TMEM176A,CNTNAP1,ANAPC13,RNF39,HDAC6,PBLD,PIP5K1A,PSMB6,ZCCHC17,IZUMO1,PEG10,BAHD1,DHRS7B,TOMM20,TRAF3IP2,PTGER4,NLRP6,CHRDL1,SRC,CD2AP,VPS28,MPZ,TUFM,GNG13,IFNA2,IDH1,METTL6,RASL10A,MKKS,SLC35B4,MORC4,CISD1,LANCL1,PIK3R3,MED31,SH3BP5L,CELF6,FCGR2A,NAA50,TUBA1A,YTHDF1,RPL7,CHST11,HMX2,ICAM3,UNC50,MTMR6,NEUROG2,LUM,SEMA6C,CCDC85B,HNRNPD,MS4A7,SLC25A11,KCTD15,PSMD12,CKLF,CCT7,RGS19,RASGRP3,ENTPD3,RCE1,MGAT1,MCM3,CDC42EP3,RNF115,IFIT2,RAB33B,SECISBP2L,GLT8D2,FAM162B,SPATA6,VTI1B,ARHGAP5,ZNF575,MRPS7,CCL20,PCDH9,ZRANB2,LIN7B,RIC3,ARHGAP25,DES,TCAP,EIF4E3,MYOZ3,LRIF1,TMC7,FTL,STIM1,GRPEL2,FLRT3,TNFSF13,ZNF668,CD248,RSRC1,RPL35A,SLC25A28,SLC39A3,FLCN,CXCL12,MSL2,KLHL12,SERPINI1,IDO1,PPM1D,YBEY,NTPCR,IL15,MRPL10,CYP27B1,PNOC,TLE1,ARL6IP6,HMG20A,BTF3L4,RRN3,DHPS,UTS2,NIF3L1,GNG5,TMEM14B,NDUFB10,POMT2,POLR2F,NSFL1C,TMEM190,SCPEP1,IFNGR1,RIMS4,NDUFA2,SCN3B,NMI,MOG,LRRC57,PLSCR4,ISCU,FCHSD2,ELAVL2,MOSPD1,TRIM10,SLC6A12,UBE2E3,UBE2M,PIR,AGAP1,CYP2F1,PSME1,KBTBD4,PNO1,CLVS1,FAU,AK5,RAB22A,SMC4,TNNC2,GTF2E1,SMAD4,SLC22A8,DRD1,SLC1A3,RILPL2,FZR1,GPR85,PPP2R3A,ELK4,FAIM,BAK1,ATP1B1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B,TMEM117,MRPL34,NDUFB6,RHEB,FBXL14,DHX15,RPS7,NPPC,PSMD4,TRIM15,RELL2,GRAP2,RAB27A,SLC6A6,CCDC134,SLC30A7,TCF19,ZNF664,MLC1,MAT2B,PDHB,DDX46,GANAB,RPS6KA4,TSPAN18,XCL1,BBS5,LARP4B,STX11,PMP22,SERPINA1,MRPL11,SCLT1,LRRTM3,DAAM1,HSPA13,ANKRD34B,UBB,SH2D1A,SLC11A2,PPP2R5E,NPSR1,LMAN1,MRGPRX3,SUFU,CCDC86,MTA2,LAPTM4A,FBXL19,CHIC2,CHCHD4,SLC38A7,PGGT1B,KCNC1,METTL21A,POP5,PSORS1C2,CHAC2,G3BP1,FGFBP1,MFSD5,MRPL18,NUF2,HINT2,TMEM101,SLC16A1,RPS27A,PCDHB13,ELOVL7,RAPGEF5,DBT,TPD52,DSTN,DAPK3,CHPF2,NDUFAF3,IER2,COMMD3,BMPR2,PPP1R1B,RND2,OLFM3,SCG3,CCS,RASD1,SHISAL2B,SCGB1D1,ILDR1,NLRP3,ILF2,ZNF365,BAG3,KDELR1,TOM1L1,RRM1,RBM22,RPS16,KRAS,CNTN2,ASNSD1,DKK1,HERC4,NR2F6,PSMB1,ZMYM3,CRIP1,GDE1,TMEM14A,PCGF3,GPX5,CPSF2,CDH8,PNPLA8,MYEF2,TAF5L,MOV10,NGB,UQCR11,GLT8D1,SLC43A2,ZCCHC9,TMEM91,TEX12,B3GNT2,HIGD2A,TOP3B,GRIA2,LRRC24,FLYWCH2,MRGPRX2,DDX4,KLK5,LIX1,CAB39,AMY2B,RBMX2,NDE1,HMBS,CD2BP2,TDRD7,LDHAL6B,CCDC65,LY6G5C,UBE2D1,SNIP1,SLC4A8,ACTL6B,FAM168A,RAB1B,INHA,RPAP2,RGS5,ZBTB45,ABHD13,HRH3,SOS2,PIWIL2,AKIP1,SLC23A2,GYS1,PGM2L1,ROGDI,FOXN2,RBFOX2,CDKN1A,GK2,ELSPBP1,STX18,SLITRK2,SDHAF2,MED11,CLIC2,PPFIA3,STK38,TIMM10,PCDH19,PNP,RAB5C,WEE2,AP1AR,FOLR1,SLC6A11,RAB37,IFI35,FBXO25,PSRC1,CSTF2T,C1QL1,CAV2,TIMP1,DERL2,TXNL1,PLEKHJ1,MLF2,LYNX1,RPL23A,IL6ST,TMEM59,EIF4B,PPP2R1A,SLC25A4,MRTO4,PTHLH,SMAD3,PHYHIP,WIF1,FN3KRP,DYRK1B,SNX24,ACADSB,ISG15,STAT6,ARCN1,EZH2,FGFBP2,INPP4A,KCNIP3,AMT,RAB9B,CD226,SACM1L,VPS33A,CRBN,PDYN,ZFP1,B4GALT3,BEND5,SNRPA,CMPK1,TRAPPC6B,CCNF,VAMP2,CTNNA1,RAB2A,GPIHBP1,WDR44,CCL8,RFTN2,TPPP,SLC35E1,RB1CC1,CAPZA2,YPEL5,PPID,RCBTB1,GGCT,ATP6V1C1,HNRNPA2B1,MAPK1IP1L,OR2A25,STX6,FANCG,PLA2G15,PRKAG1,HNRNPK,NFKB1,ACAP2,SCD5,MAFG,LHFPL2,EGLN3,CLDN22,DYRK2,FOS,POMP,RPL26,RIOK2,MRPS28,DNAJC8,PPDPF,TNFSF18,RNF167,FAM107A,RAB33A,CRYGD,TNRC6C,SPTBN1,CHI3L1,RNASEL,GNPNAT1,GIMAP2,TOMM40L,FERMT2,EIF3J,UTP23,WWP1,RHOJ,CBLN4,CD47,S100A8,HIRA,TMEM50B,JUN,IFNG,ZNF687,CCR3,SUMO3,PTGER1,CMAS,RAB23,SFT2D2,KCNK10,SLCO1A2,ZNF609,TMCC2,SELENOS,KRT7,PLEKHA8,MANSC1,WDR3,GJB2,SRP14,TMEM106C,ACTR2,CRYBB3,TAS2R5,TMEM203,FOXS1,PTRH2,SYNJ2BP,ACP6,TMEM164,TRAM1L1,PLAGL1,SESN2,RFXANK,KLHL15,GCA,UPF3B,ISCA2,RABL3,ZNF576,MPV17,CHST1,FCHO2,EHD1,PPP1CB,TRAM2,SLC7A14,DDX42,PPP1R16A,MT2A,PXMP2,ATP1A2,CYB561D2,GMPPA,TUSC3,RPL6,CLDN8,CXCL14,ADAMTS1,BNIP3L,KIAA0408,RNF122,BICD2,CREB1,SERPINA5,TMEM177,FMO2,RAN,RPP25,RBM12,GLIPR1,SQSTM1,POLR3B,BRD9,PGR,HAND2,CXCR4,HSPA14,NPY5R,CCL17,KIAA1191,DLG4,GTF2F2,KCNH1,ADIPOQ,ANKRA2,ERH,ALKBH5,CRTAP,LCP2,UHMK1,ABHD6,CLDN1,METTL2A,TFCP2,NDUFAF4,CRYBB2,AKAP14,CTDSP1,CCNB1,FAM162A,SMU1,SLC35D1,COL1A2,RMI2,SAT1,CSGALNACT1,R3HCC1,GNG2,EDEM1,METTL14,VAMP5,PTS,TOR2A,JPH4,AMIGO1,MBL2,MAP3K11,TMEM184B,KDM4B,ZNF287,ACAT1,NKIRAS1,GIT2,SDF2L1,RUVBL1,CXCL3,GTF2B,RAB3D,CLDN4,LAMB2,SLC13A5,POPDC2,GPX6,TGIF2,GREM2,PDCD4,LDOC1,GPAM,CREBBP,PRPF19,RDH10,HTR1F,TRIM54,RPLP2,ACBD7,FAM98A,CDC42SE2,SEC61B,GPR65,TOM1,BCL7B,DNAJC22,EIF2B3,HTR5A,TMX3,TCF23,CHGA,GBE1,SNX17,BCS1L,APOO,GPR137,NRSN2,TOP1,TMEM144,GCNT3,F9,NKX3-1,NDUFS8,CYP2C18,MYO6,ARMC7,ATAT1,CIDEB,IPO8,TMSB10,ZC3H7A,AIF1L,ZBTB5,DSTYK,TMEM123,MRPS23,FUNDC2,SYP,ATG4A,ZNF862,CSRNP1,RGS7BP,CDKN2AIP,SFRP4,RER1,FCN2,ISG20L2,GPHN,POLE4,HSP90AB1,TSPO2,GOLGA7B,RNF113A,EFNB1,THTPA,SH3GLB1,PREPL,TFE3,IFNA10,DEFB114,MT1M,ITGA6,CSNK1A1,PELP1,COMMD8,NTN4,RTKN,FUT9,PHYH,UBE2V2,IL10,RPLP0,RINT1,BZW2,TSPAN5,OR10G9,SPECC1L,KHDC1,NAT2,CD274,B3GALNT1,CREB3L4,EIF3K,ZBTB17,BCAP29,FABP7,AKAP12,IGBP1,SSU72,DDX39A,RAB40AL,SNAPC3,BLOC1S2,SNCG,LHFPL4,COX4I2,CDKN2C,TMSB4X,TRIM5,EIF4E,B9D2,EWSR1,TMEM204,PROS1,MRPS16,ABHD14B,EED,MTRF1,ZNF592,ELP3,YAF2,ACSL4,TGFB3,TRIM24,MRFAP1L1,CIB2,ADO,CALHM2,GMPPB,BECN1,LMNB1,CCDC25,TES,CHMP2A,EMP3,MSMP,HSPA8,VMP1,SLC19A2,CBR4,STAU1,STOML3,TSN,SLC41A3,SERINC3,RNASEH1,DNAJC3,TMED7,KLK6,FKTN,MBD5,NOS1AP,BCL10,KCNMA1,ADPRH,PDHA1,NME1,DUSP19,RGS2,STMN2,CNNM4,NR1I2,DPY30,NPR2,CDK4,RBM7,TRAF2,KCNK13,BRCA1,ABHD4,PCDHB1,RAC2,STK24,LCA5,PYROXD2,MRPS21,LRP6,TAS2R40,PARP11,SLC32A1,ST3GAL5,POR,ZNF501,CEP97,IFRD2,DERL1,IL18,ST3GAL1,CSNK1A1L,SOX2,PAX9,STXBP1,KLC2,PCMTD2,MTHFD2L,IRF3,UQCRH,DPEP1,PRKAB1,FRMD8,RFX4,ZDHHC14,PKNOX1,ADRB1,PCDHB8,RBM17,HEY2,TRAPPC1,FAM199X,RABL2B,NIPA2,CLDN11,NPY2R,LRP12,SLC35E3,SPTAN1,RNASET2,PTPN1,HNRNPC,SETD5,NFIL3,ZBTB38,TRIM37,HECW1,RBBP7,SLC25A21,PGS1,RMND5B,ARMCX2,ACTA2,TRIM21,SIX5,ARFIP1,GALNT12,PPARG,SPR,SORD,SBK2,CCT5,ENPP4,MCOLN1,PSMB5,AGK,FBXO32,ANAPC2,PRPF4,ARMCX5,ZNF593,IDH2,FKBP14,RAB18,IMPACT,CD58,AGER,CAMK2G,TMX4,BUD31,SRP54,CIB3,TACR3,PRMT2,GHITM,CACNB4,TUBG1,RPL15,CCDC47,TTC4,SCFD1,SHC1,PYGM,CAMK2N1,HCRT,FGFR1,KCNJ11,CRYGB,PPP3CA,CD200R1,CCDC127,FAM89B,RCVRN,PEX3,UBAP1,ZYX,CDC73,LHX2,S100A6,DYNC1I2,CYP27A1,BTF3,MMP9,PGK1,ROPN1B,VRK1,SNAP91,MYH2,HEBP1,SLC7A9,ALKBH4,TMIGD1,DNAJC5,KPNA1,PIWIL4,CSNK2A1,RARRES2,KBTBD2,GSTO2,ATF4,CTNNBIP1,GNG7,JOSD1,SUPT7L,LSM3,AFTPH,RS1,KIT,PSME2,AZIN1,FGF1,INO80C,AZGP1,ABCB1,HBE1,LBH,JAK1,MAGOH,CCL19,NKX3-2,TBC1D10C,MLF1,GTF2E2,TNFAIP8L2,DEFB116,DHRS3,NDST1,KTI12,RAB3B,CDCA3,SMAP2,ATP6V1G1,FZD4,MEST,WDR77,MTPN,MX2,GPBP1L1,SYN3,ZCCHC10,AAMP,LYG2,MFSD6L,ZNF24,FBXO42,TMEM215,TSEN54,SERPINB10,IMMP2L,MEF2A,DHRS4,SLC35A1,ENY2,RAG1,SNAPIN,SLC30A5,KLK3,MRPL50,MRPL24,ZNF304,IL15RA,SLC38A9,MIOS,FAM78A,PPP1R2,RMND1,IDH3B,CYP11B1,GRM2,CTNNBL1,SENP5,GPAA1,JAKMIP1,TLR3,FAM8A1,ITK,EIF4H,NCR3,CYP39A1,HSD11B1,MYL12A,SWAP70,GNRH2,CHDH,CDK5R1,NCKAP1,NRP1,GLUL,CNIH4,LMO4,KIAA0232,ATPAF2,CLU,CCR6,SLAMF9,ZMYND19,TAAR1,XAGE5,ID4,ZNF319,SEC14L1,APOBEC3A,ZNF397,CCT2,UBE2D3,ATP6V0E1,ARMCX1,UBE2A,TRIM23,NAIF1,NHP2,IRF1,STRBP,ING1,GAL3ST1,CASK,LTBR,PRPSAP1,TCP11L2,GRPEL1,ELMO1,FGFR1OP2,GABARAP,ARHGAP1,DOK4,PLA2G5,KLK9,KLHDC8B,RNF141,TRIM32,UBR7,PDIA6,SDR42E1,CD99L2,PRIM2,SNRNP27,ZMPSTE24,EXOSC1,EFCAB7,GPR89A,E2F6,GFM2,MRPL23,GDI2,ZNF207,ATP6V0B,TMEM219,EDF1,TRIM3,C1QC,TMUB1,POLR3H,SLC17A5,ZNF671,SLC25A31,LYPLA1,RPS14,LIG3,UGCG,MEAF6,SF3B4,IL20RB,DKK3,CRABP2,DPP10,PRRC2A,CDO1,CCNI,PPIL4,RAB11A,TLR9,L1CAM,WDR38,SNX20,FIBIN,APEH,FGD2,DLX1,AKT1,FNDC8,COMTD1,GALNT1,SOCS5,AK2,PSMA3,CCDC69,GSTO1,TMEM156,MRPL13,EHBP1,MGP,MDM2,GNRHR2,TOM1L2,PFDN5,EXOC8,UST,LYAR,NUDT3,B9D1,RND3,CNP,SLC5A6,CYP4F8,PRKD3,NLGN2,DEK,SCAMP2,SPEF1,CD164,PPIB,BPGM,CDKN3,RBCK1,MRPS25,AKR1A1,NOP58,SPATS2L,NFE2L1,MRGPRX4,FABP5,CTSD,PGAP2,INPPL1,BACH1,MIA2,KIF2A,PTDSS1,ID1,ARMC8,SLC35A2,ENTPD4,CCDC42,NPTN,FCAR,POU1F1,CYC1,CRYBA2,DEGS1,SETD4,LCN6,FBXO9,COX7A1,RPGRIP1L,OR2W1,CCND1,WFDC13,ACOT13,TMED3,KLF10,AP3S2,TMEM33,S100PBP,MRPL47,MPHOSPH10,SPINK13,RHCG,ARHGAP21,SCG2,FAF2,BMPR1A,CTSK,CACYBP,CETN3,URM1,PWP2,RAB3C,MTAP,STX8,TGFB1I1,DUSP1,BATF,TOLLIP,NFYA,S100A10,FAM200A,CHST9,CPT2,ANP32B,AP1G2,NDNF,CDK6,CWF19L1,DCAF5,ESR2,SNRPD2,ADCY3,CLEC12B,SFTPD,CYP2D6,SOCS2,INTS12,RAB8B,CTNNB1,PRKX,FGF13,PROX1,SYNGR1,RTP4,ZMAT5,LSM6,ENPEP,NAB1,SLPI,USP39,CERK,USP38,ZNF174,H19,SPRED1,POLL,NONO,TSSC4,MAK16,ALDH1L1,OR2A2,EIF4EBP2,SOST,TCP11L1,SV2B,HPCA,SNTA1,SNAPC1,GPR37L1,NDUFAF2,GFOD1,SIVA1,TNFAIP3,RAP2B,ABHD16B,MTMR12,DUOXA2,MMACHC,TRAF7,FYTTD1,NOL4,IQSEC1,SIRT7,ETV6,RRAGA,TAPBPL,NEDD8,CXCR1,FGF17,HBB,TRMT6,PTCRA,CCL21,NDUFA5,KCND2,IL34,DFFA,ST13,RASGRP2,LPXN,FBXO30,TIGD7,CD2,POLR2I,UCKL1,ACAA2,RAP1A,WWP2,RABAC1,CD3G,BRMS1,GAS8,KIF1C,CHRNA7,CDKL2,IGFBP4,NPVF,LMBR1L,AKR1C2,TAC1,NQO1,IPP,TBCE,SPATA2L,ADAT1,HEXA,BRI3,RBM23,TMED1,STAMBPL1,SIPA1L1,PGBD2,HSPE1,CLDN14,ZKSCAN1,RPL37A,SERPINH1,DHX16,RAB4A,SOX21,TRA2B,HADHA,LEAP2,B4GALT6,HSPB1,KCNA2,LHFPL1,NUDT16,GXYLT1,PDIA3,FRA10AC1,XPOT,EIF1AD,NAA11,ISYNA1,NDUFB8,APH1A,LEPR,STX17,WNT7A,RPRML,MSX2,KRR1,NLE1,SNAI3,PELI3,CDC37L1,CCL25,GNMT,TXNIP,CREBL2,AQP4,GLE1,EIF4EBP3,WDR37,ZSCAN1,FURIN,SLC39A9,DHX9,IL23A,PSMD6,GALE,EIF2B5,SH3GLB2,ENDOD1,CIRBP,CXXC5,LASP1,PHKG1,SPOCK1,UTS2R,NEK7,WBP2,GTF2A1,FUT8,XPO1,EXOC2,THRAP3,EEF2,GJA10,EFHC1,SLC25A32,TF,CREB3,RNF103,XPO5,SURF4,INTS10,GPR162,APOBEC3C,RNF187,SLC7A4,ZNF513,ZMYND11,SLC20A2,PCDHA5,PFDN6,LDHA,NUBP2,UBXN10,PRCC,GSK3A,ABCC5,THOC1,NUDT19,RANGRF,RC3H2,DNAL4,FATE1,ATP2C1 |
| 8.274e-24 | -53.15 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 14773 | 4431 | 16828 | 4835 |
RUSC2,CD9,GADD45A,IGFBP3,GRPR,TMEM183A,DPEP3,BTG3,THOC3,BOLL,MX1,GLOD4,PIGA,VPS54,SLC25A27,TGFB2,RBMS2,ZNF622,ATG9A,S100A11,SPG21,TIA1,SLC22A6,DDR1,TMEM81,EXOC3,SAP18,CAP2,NPC2,TMEM115,PNPLA4,LRRC28,TCEA2,PARD6A,RNASEH2C,HSPD1,EIF1AX,GNA11,SERTAD2,HSPA5,HSPB6,THAP8,WDR45,MPV17L2,CRYBA1,NRM,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,NR1I3,LRP10,TRIM44,TMEM229B,GNB3,HINFP,NUFIP2,CMC1,VAV2,CCDC3,ITGB8,BTG2,RNF10,POLE3,GP9,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,POLR1D,GPR160,DTWD2,PSMD3,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,TEX261,IP6K1,IL2RB,PTGFR,FBXW4,ST3GAL2,TAS2R7,CD209,TRIP4,RPL10,STAR,SUPT5H,PDCL,SLC25A24,SPINK9,GLCE,GK5,SSNA1,CPXM1,THAP1,CD34,FBXL4,PRCP,EID2B,DCTPP1,OR4A47,GADD45G,YPEL4,LDB2,TMEM107,RPA2,RGP1,CCDC90B,PIWIL1,TRAF3IP3,SRPK2,TAB2,MED22,ARFGEF1,NOG,PMPCA,TLR8,CD40,AIP,TNFSF15,SLC6A2,CRY1,PLAC1,SCAND1,PSMD7,SIN3A,CDK7,RAB6A,CTTNBP2,RGN,ZNF428,PDE2A,CDIPT,TNFSF8,PYCR2,CIAO1,ATP8A1,KIF3C,GHRL,VPS18,ZNF581,PDE7A,DUSP3,SUCLG2,SCML1,TAPT1,MED10,TYMS,ZFAND6,NAA16,RPS20,RUNX1,SLC12A2,GJC1,YTHDF2,FAM161A,PDE12,ANKRD6,PFKFB2,ARHGAP12,EIF5B,SRFBP1,DIRAS2,MREG,ACER3,SSBP4,RASSF8,KCTD17,CLEC6A,RBP2,TLCD1,AQP11,LCORL,EDA2R,FKBP1B,LMO2,PSEN1,MAGEC2,MDC1,TRAPPC6A,SP1,ITM2B,MTCH2,MGMT,TRAM1,TADA3,FUNDC1,ECHDC1,AP1M1,UBA52,TMEM196,IMPA2,RPS10,SPRY1,CCDC106,ETNK2,CLDND1,GIN1,TKTL1,RPL18,TBCCD1,TRAF6,ROCK2,KCND3,FUBP3,VPS72,KRIT1,FXN,UPRT,SUPT3H,MECR,SGIP1,MRPS17,FEM1B,UBE2G2,MRPL9,IER3,NUCKS1,CENPL,KLRC2,TOX4,TMBIM1,CPNE2,CYTH4,IFT172,RAMP3,PTP4A2,FAM3C,MFAP3L,SLU7,VEZT,IRF7,KLHL25,TMEM165,RPE,SULT1B1,FAM151B,ZNF518B,MACROD1,CYBRD1,ADCK1,FAM136A,SLC35E4,SLC25A5,PRR13,WSB1,LYZ,TOPORS,SYNGR3,TANK,BRAP,MPG,DMPK,CDC23,MBD3,LRRC8A,SSPN,GNGT2,CNPY1,HAUS2,GALC,ELFN2,RP9,LBX1,NKAP,RDH11,KCTD3,PIH1D1,IL18BP,RASL12,ANXA4,GALNT2,RRAGB,SNRPE,DLGAP4,CMA1,GRIK1,CCR7,IGF1,RXRG,SNAP25,THUMPD1,GORASP2,TTC9C,GMPS,PELO,UBE2E2,RHOBTB3,HGS,POLDIP3,POLR2L,FSTL1,MT1E,CRISP1,LRRC40,ELK3,DPH3,CD81,COX6B2,TMEM170A,RNF133,ZNF451,PRKCE,GNRH1,WDSUB1,PRKRA,TSPAN17,DBR1,TAS2R13,SESTD1,CARTPT,KLHL1,FOXA3,PARP2,NF2,ABHD12,BANF1,PHF13,RPL26L1,CGGBP1,SNRPB2,LZTFL1,TFB1M,CCR4,CHRAC1,KLF3,TNF,GGH,NUDT9,CYGB,IL17F,PPAT,SLC19A3,FBXO8,NDST3,MPPED2,PRL,CDC7,IGSF11,CYP2C9,MRPS34,TRIM45,ATAD1,DUSP21,RBBP8,MGAT4A,SGMS1,ACCS,TIMP4,XRCC5,SNRPG,ZDHHC4,WDR5B,CDC20,IL2,SEC13,TNFAIP8L1,VMAC,NBN,AIPL1,PEX13,TBC1D25,TYROBP,WDR11,NHEJ1,SLC35B3,FHOD3,CBX3,DR1,HS2ST1,GTPBP8,LYPD6,ELMO2,TRPC1,ASPA,BCL9,HSD17B10,CAND1,PRNP,GABRA1,TMEM89,MIS12,SNX10,CA2,SGTA,MTDH,USP6NL,ZNF263,TPPP3,SSX2IP,BCL6,GSTCD,E4F1,TMED9,GTF2F1,DLST,TMEM185A,NDUFS2,SNRNP40,FAM83B,PIK3CA,IVNS1ABP,CDH11,PSMC3,JAKMIP2,CNN3,CPT1B,ZBTB39,RBM27,ANKMY2,TMEM47,MAD2L1BP,LY96,AP1S2,APEX2,ADORA3,TAB1,SF3B1,AKR1B1,FEM1C,COCH,LST1,COX6C,PICALM,XAF1,PIK3AP1,RPIA,VTA1,GSTM4,CRTC2,NPM3,TSPAN15,TMEM38B,NUDT2,PSD2,GH1,BAX,PEBP4,ATP1A3,ZNHIT6,GPR17,GPC1,PLCB1,PRSS23,SPP1,FRZB,CHRM3,TSR2,ARL2BP,ING2,PSMB7,TNFAIP6,FBXW7,PLG,DMTF1,CDK12,DLK2,TXNDC17,CITED1,ARL4D,LIAS,NPY1R,GCLC,PSMD10,TNNI3K,CPLX3,CTU1,EPHA4,KCNJ2,SLC25A1,STAMBP,HNRNPF,ZNF511,EHD4,CEND1,FAM81A,GRM1,PCGF6,TAF1D,KCNJ10,SHPRH,SPATA2,ADORA1,SLCO3A1,HOMER3,MAGEB10,CXCR3,RNF222,REEP4,AASDHPPT,CCNA2,TM4SF20,GJA1,MAGED2,SLC29A1,SURF2,TNR,TM4SF18,BOK,SLC8A1,LSM14A,CAPN2,STARD3NL,YWHAZ,ICAM2,ABHD8,HUWE1,ABHD10,CPLX2,PRND,SREK1IP1,CNTROB,FTSJ1,AKR1C1,CSNK1G3,RAB39B,MRPS11,CYP3A43,SPEM1,PDE4B,CCIN,UBE2L3,TTPAL,PMAIP1,EIF3G,MEPCE,YIPF3,TCEAL8,LXN,RPS2,CAV1,B4GALT4,ICOS,NINJ1,RGL2,ITGB5,NDUFC2,TMEM205,TRIM34,RB1,TRIM29,CORO6,DPH5,PNMA3,NDUFA1,GPR35,DDAH1,HFE,ALG11,MCL1,FAM53C,GSTA2,TMEM127,HCAR1,MRPS18C,NT5DC1,TRIM36,JAK2,PROK1,CREBZF,DCAF12L2,PLSCR1,PTP4A3,HSPB2,COMMD9,STK3,CBLN1,LILRA2,TNKS2,LY6H,ZDHHC24,B3GALT2,PPT1,ARF6,MRPL12,FGR,SPHK2,RCHY1,LSM12,FIG4,CXXC1,RPL7A,DCTN4,MAP2K3,SEC22A,DOK5,RIT2,CACNG3,ZC4H2,CETN2,TADA1,CBFB,ZC3H14,ASPM,EFNA5,SH3BP4,LEP,PITHD1,SMARCE1,UBE3A,OR5K1,PDZK1IP1,PDE6D,LRFN3,TNIK,S100B,RPL19,IL21,SLITRK5,DDIT4L,RNASE4,SAP30,FGF16,MSN,POU5F1,HBM,ZNF362,SLC6A7,MAGEB1,DICER1,PLEKHF2,SNRNP70,SERINC1,GLIPR2,MID1IP1,SPCS1,TDP1,MED29,UBE2I,UCP2,TMEM106B,MFAP1,MXD1,SLC41A1,LAMTOR2,PNRC1,EZH1,ARGLU1,TECR,MRPL16,RNF7,MAP3K3,ARL11,FHIT,ASB11,RGS1,SDHC,RHOG,NOL12,FAM83A,CDC42SE1,COX7B,BGLAP,METTL18,RSBN1L,GAD2,SEC61A1,TTR,TPD52L1,ZNF770,UBXN2B,DUSP18,SVIP,SMUG1,CDH7,ASCC1,CXCL10,FBLN5,FOXD3,LYRM2,MAEA,KIAA1958,EID2,ZNF345,GPR83,LPCAT3,PHTF2,ZCCHC7,PPIL3,CTSA,DPAGT1,HNMT,ERRFI1,FA2H,SERTAD1,KCNIP2,ZHX1,ZMYM6,EIF2B2,ARF1,GNG11,HMGB1,PHF7,MRPS26,CKB,THAP6,TUBA1B,ZBTB26,LRRC14,PDCD5,PRDX3,EMILIN1,BTBD10,CKS1B,DYNLRB2,HBP1,RPL4,RGL1,SUV39H1,DCTN3,LSM5,IRF2BPL,PRKCB,HCFC2,RWDD1,SLC25A3,RBM41,COPE,TPST1,ZNF200,IZUMO2,HNRNPH3,LCP1,AGGF1,CSF2,PCYT1B,PRELP,KRT8,GJB1,GCHFR,CHCHD2,SKP1,TTLL10,ATG16L1,HDAC11,SIGLEC5,DIRAS3,TP53TG5,PSMB10,CDK17,TMEM39A,ART5,ATP6V1D,CDKN2D,ESD,GPR37,VWF,CLP1,CLPX,ATG3,INA,CFTR,MYLIP,SUPT4H1,FAM174A,VPS39,IFI16,PTPRZ1,SART3,PSMD1,BARX2,MPP1,ADH1B,MED27,RANBP10,SRM,BMPR1B,TULP3,HS3ST1,MLH3,PCBP4,APOBEC3B,BLVRA,CRYZ,FOXC2,PITPNA,RAB32,CRYBA4,CCND3,RAB11B,ARL6,STX5,LEMD3,CSRP1,IRF4,TBC1D16,SLC7A1,CA12,SPATA4,CMTM7,ADRB3,FMOD,PLP2,DUS4L,ABCF1,RNF139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,CLEC1A,PCSK9,PSMA6,KBTBD3,TTC23,PCBD1,AGR2,CACNB3,TMEM174,MORF4L1,NLGN1,LCN8,CPSF4,AGA,CD63,SYK,SLC25A26,VPS16,ACO2,CLN8,CDC42,SLC48A1,TNFAIP8L3,DUSP10,BACE1,SLC38A1,PIWIL3,IL2RG,SNX1,FTH1,CCM2,ALB,SLC35F1,PSEN2,CYTH2,RNF11,SYNGR2,TAF7,APOC4,TLR10,WDR82,NAB2,FXYD6,ZBTB25,CD28,ZNF473,KIAA1143,SELL,GNL1,DNAJC2,GNB1L,ATP1B3,PPY,CRYAB,ROMO1,LAMP3,CNOT6,CHPF,MATR3,REEP6,AGTRAP,CRADD,PPP1R3C,KCNAB1,APBB3,MCMBP,SEMA5A,S1PR4,TMEM11,TNFAIP1,FAM169A,BRIX1,IRGQ,CFL1,KLHL3,RNF40,RPS26,KDELR2,DAP,DDX1,TP53I3,RNASE6,DPM2,CYP2R1,GOSR2,SLCO1B3,FGF23,RANBP6,G6PC3,SLC25A39,CD14,PRR5L,CCL27,ZC3H11A,SFRP1,WSCD1,ELF1,HTR1A,TMX2,CD86,MANBAL,PNMA5,ENO2,PSENEN,SLC2A8,ZNF704,UBE2H,FARSA,PTPMT1,KBTBD6,APOBEC3A,ZNF397,ID4,ZNF319,SEC14L1,XAGE5,TAAR1,SLAMF9,ZMYND19,CCR6,ATPAF2,KIAA0232,CLU,LMO4,CNIH4,GLUL,CDK5R1,NRP1,NCKAP1,GABARAP,FGFR1OP2,GRPEL1,ELMO1,TCP11L2,PRPSAP1,LTBR,CASK,GAL3ST1,IRF1,STRBP,ING1,NHP2,NAIF1,TRIM23,UBE2A,ARMCX1,CCT2,ATP6V0E1,UBE2D3,RMND1,MIOS,FAM78A,PPP1R2,IL15RA,SLC38A9,ZNF304,MRPL24,MRPL50,SLC30A5,KLK3,SNAPIN,RAG1,ENY2,DHRS4,SLC35A1,IMMP2L,MEF2A,CHDH,GNRH2,SWAP70,HSD11B1,CYP39A1,MYL12A,ITK,EIF4H,NCR3,FAM8A1,TLR3,GPAA1,JAKMIP1,SENP5,CYP11B1,CTNNBL1,GRM2,IDH3B,FNDC8,COMTD1,DLX1,AKT1,APEH,FGD2,L1CAM,SNX20,FIBIN,WDR38,TLR9,PPIL4,RAB11A,CCNI,CDO1,CRABP2,DPP10,PRRC2A,SF3B4,IL20RB,DKK3,CNP,RND3,B9D1,NUDT3,LYAR,PFDN5,EXOC8,UST,GNRHR2,TOM1L2,EHBP1,MGP,MDM2,MRPL13,GSTO1,TMEM156,PSMA3,CCDC69,GALNT1,SOCS5,AK2,GDI2,MRPL23,GFM2,E2F6,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,CD99L2,PRIM2,SNRNP27,SDR42E1,UBR7,PDIA6,TRIM32,RNF141,KLHDC8B,PLA2G5,KLK9,ARHGAP1,DOK4,MEAF6,UGCG,RPS14,LIG3,LYPLA1,ZNF671,SLC25A31,SLC17A5,POLR3H,TRIM3,C1QC,TMUB1,EDF1,ATP6V0B,TMEM219,ZNF207,CD58,AGER,IMPACT,RAB18,IDH2,FKBP14,ZNF593,ARMCX5,PRPF4,AGK,ANAPC2,FBXO32,MCOLN1,PSMB5,CCT5,ENPP4,SORD,SBK2,CCDC127,FAM89B,RCVRN,PEX3,PPP3CA,KCNJ11,CRYGB,CD200R1,FGFR1,HCRT,CAMK2N1,SHC1,PYGM,TTC4,SCFD1,CCDC47,CACNB4,RPL15,TUBG1,GHITM,TACR3,CIB3,PRMT2,CAMK2G,TMX4,SRP54,BUD31,RNASET2,SPTAN1,SLC35E3,NPY2R,LRP12,NIPA2,RABL2B,CLDN11,FAM199X,TRAPPC1,HEY2,PCDHB8,RBM17,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,SPR,PPARG,ARFIP1,GALNT12,ACTA2,SIX5,TRIM21,ARMCX2,RMND5B,PGS1,RBBP7,SLC25A21,ZBTB38,TRIM37,HECW1,NFIL3,SETD5,HNRNPC,PTPN1,SMAP2,CDCA3,RAB3B,KTI12,NDST1,DHRS3,TNFAIP8L2,DEFB116,MLF1,GTF2E2,NKX3-2,MAGOH,TBC1D10C,CCL19,JAK1,LBH,HBE1,AZGP1,INO80C,ABCB1,FGF1,AZIN1,PSME2,TSEN54,SERPINB10,FBXO42,TMEM215,ZNF24,MFSD6L,LYG2,AAMP,GPBP1L1,MX2,ZCCHC10,SYN3,MTPN,WDR77,FZD4,MEST,ATP6V1G1,DNAJC5,TMIGD1,ALKBH4,SLC7A9,HEBP1,SNAP91,MYH2,VRK1,ROPN1B,PGK1,MMP9,BTF3,CYP27A1,S100A6,DYNC1I2,LHX2,ZYX,UBAP1,CDC73,KIT,RS1,AFTPH,LSM3,SUPT7L,JOSD1,ATF4,GNG7,CTNNBIP1,GSTO2,KBTBD2,RARRES2,KPNA1,PIWIL4,CSNK2A1,GXYLT1,NUDT16,LHFPL1,B4GALT6,KCNA2,HSPB1,LEAP2,HADHA,RAB4A,SOX21,TRA2B,DHX16,SERPINH1,RPL37A,CLDN14,ZKSCAN1,HSPE1,PGBD2,SIPA1L1,STAMBPL1,CDC37L1,PELI3,SNAI3,NLE1,KRR1,MSX2,RPRML,WNT7A,LEPR,STX17,ISYNA1,APH1A,NDUFB8,EIF1AD,NAA11,FRA10AC1,PDIA3,XPOT,WWP2,RABAC1,RAP1A,UCKL1,ACAA2,CD2,POLR2I,TIGD7,FBXO30,LPXN,RASGRP2,ST13,IL34,DFFA,KCND2,NDUFA5,CCL21,PTCRA,TRMT6,HBB,FGF17,NEDD8,CXCR1,TMED1,RBM23,BRI3,ADAT1,HEXA,TBCE,SPATA2L,NQO1,IPP,AKR1C2,LMBR1L,IGFBP4,NPVF,TAC1,CHRNA7,KIF1C,GAS8,CDKL2,BRMS1,CD3G,ZMYND11,ZNF513,SLC7A4,RNF187,GPR162,APOBEC3C,SURF4,INTS10,XPO5,CREB3,RNF103,TF,GJA10,EFHC1,SLC25A32,THRAP3,EEF2,XPO1,EXOC2,FATE1,ATP2C1,DNAL4,RC3H2,NUDT19,RANGRF,ABCC5,THOC1,GSK3A,PRCC,UBXN10,LDHA,PFDN6,NUBP2,SLC20A2,PCDHA5,PSMD6,IL23A,FURIN,SLC39A9,DHX9,ZSCAN1,WDR37,EIF4EBP3,GLE1,CREBL2,TXNIP,AQP4,GNMT,CCL25,FUT8,GTF2A1,WBP2,NEK7,UTS2R,LASP1,PHKG1,SPOCK1,CXXC5,CIRBP,ENDOD1,SH3GLB2,EIF2B5,GALE,FAF2,BMPR1A,ARHGAP21,SCG2,RHCG,SPINK13,TMEM33,MRPL47,S100PBP,MPHOSPH10,AP3S2,KLF10,WFDC13,ACOT13,TMED3,OR2W1,RPGRIP1L,CCND1,FBXO9,COX7A1,LCN6,SETD4,NDNF,AP1G2,ANP32B,CPT2,CHST9,S100A10,FAM200A,NFYA,TGFB1I1,DUSP1,BATF,TOLLIP,STX8,RAB3C,MTAP,PWP2,URM1,CETN3,CTSK,CACYBP,CTSD,PGAP2,MRGPRX4,FABP5,NFE2L1,AKR1A1,SPATS2L,NOP58,MRPS25,RBCK1,BPGM,CDKN3,PPIB,CD164,SPEF1,SCAMP2,NLGN2,DEK,SLC5A6,CYP4F8,PRKD3,DEGS1,CRYBA2,POU1F1,CYC1,CCDC42,FCAR,NPTN,ARMC8,SLC35A2,ENTPD4,PTDSS1,ID1,KIF2A,BACH1,MIA2,INPPL1,SIVA1,GFOD1,GPR37L1,NDUFAF2,SNTA1,SNAPC1,SV2B,HPCA,SOST,TCP11L1,EIF4EBP2,OR2A2,TSSC4,MAK16,ALDH1L1,NONO,POLL,SPRED1,H19,TAPBPL,ETV6,RRAGA,SIRT7,IQSEC1,NOL4,FYTTD1,MMACHC,TRAF7,DUOXA2,MTMR12,ABHD16B,RAP2B,TNFAIP3,CTNNB1,RAB8B,SOCS2,INTS12,CYP2D6,SFTPD,CLEC12B,SNRPD2,ADCY3,DCAF5,ESR2,CDK6,CWF19L1,ZNF174,USP38,USP39,CERK,SLPI,NAB1,ENPEP,ZMAT5,RTP4,LSM6,SYNGR1,PROX1,PRKX,FGF13,UTP23,GNPNAT1,GIMAP2,FERMT2,EIF3J,TOMM40L,RNASEL,CHI3L1,SPTBN1,TNRC6C,CRYGD,RAB33A,FAM107A,RNF167,PPDPF,TNFSF18,DNAJC8,CMAS,RAB23,SFT2D2,PTGER1,SUMO3,ZNF687,CCR3,IFNG,JUN,TMEM50B,CD47,HIRA,S100A8,CBLN4,RHOJ,WWP1,PLA2G15,FANCG,OR2A25,STX6,MAPK1IP1L,HNRNPA2B1,ATP6V1C1,RCBTB1,GGCT,PPID,YPEL5,RB1CC1,SLC35E1,CAPZA2,RFTN2,TPPP,CCL8,MRPS28,RIOK2,RPL26,POMP,DYRK2,FOS,EGLN3,CLDN22,LHFPL2,SCD5,MAFG,ACAP2,NFKB1,PRKAG1,HNRNPK,BNIP3L,CXCL14,ADAMTS1,CLDN8,RPL6,TUSC3,CYB561D2,GMPPA,PXMP2,ATP1A2,MT2A,PPP1R16A,DDX42,SLC7A14,KCNH1,DLG4,GTF2F2,CCL17,KIAA1191,NPY5R,CXCR4,HSPA14,BRD9,HAND2,PGR,POLR3B,GLIPR1,SQSTM1,RPP25,RBM12,RAN,TMEM177,FMO2,CREB1,SERPINA5,BICD2,KIAA0408,RNF122,TMEM164,SYNJ2BP,ACP6,TMEM203,TAS2R5,FOXS1,PTRH2,CRYBB3,ACTR2,TMEM106C,SRP14,MANSC1,WDR3,GJB2,KRT7,PLEKHA8,ZNF609,SELENOS,TMCC2,KCNK10,SLCO1A2,TRAM2,PPP1CB,EHD1,MPV17,CHST1,FCHO2,ZNF576,UPF3B,ISCA2,RABL3,GCA,KLHL15,RFXANK,PLAGL1,SESN2,TRAM1L1,ZBTB45,ABHD13,HRH3,RAB1B,RGS5,RPAP2,INHA,ACTL6B,FAM168A,SNIP1,SLC4A8,LY6G5C,UBE2D1,LDHAL6B,CCDC65,CD2BP2,TDRD7,HMBS,RBMX2,NDE1,AMY2B,PPFIA3,MED11,CLIC2,SDHAF2,ELSPBP1,STX18,SLITRK2,CDKN1A,GK2,FOXN2,RBFOX2,PGM2L1,ROGDI,SLC23A2,GYS1,AKIP1,SOS2,PIWIL2,GLT8D1,UQCR11,NGB,MOV10,TAF5L,PNPLA8,MYEF2,CPSF2,CDH8,GPX5,PCGF3,GDE1,TMEM14A,CAB39,LIX1,KLK5,DDX4,MRGPRX2,FLYWCH2,LRRC24,GRIA2,TOP3B,TEX12,HIGD2A,B3GNT2,TMEM91,SLC43A2,ZCCHC9,RAB9B,AMT,INPP4A,KCNIP3,FGFBP2,ARCN1,EZH2,STAT6,ACADSB,SNX24,ISG15,DYRK1B,FN3KRP,WIF1,PHYHIP,WDR44,GPIHBP1,CTNNA1,RAB2A,CCNF,VAMP2,TRAPPC6B,CMPK1,SNRPA,BEND5,B4GALT3,ZFP1,PDYN,CRBN,VPS33A,SACM1L,CD226,CAV2,C1QL1,FBXO25,PSRC1,IFI35,CSTF2T,SLC6A11,RAB37,FOLR1,AP1AR,WEE2,PCDH19,RAB5C,PNP,STK38,TIMM10,SMAD3,SLC25A4,PTHLH,MRTO4,PPP2R1A,EIF4B,IL6ST,TMEM59,RPL23A,LYNX1,PLEKHJ1,MLF2,DERL2,TXNL1,TIMP1,ACSL4,TRIM24,TGFB3,MRFAP1L1,CIB2,YAF2,ELP3,MTRF1,ZNF592,EED,MRPS16,ABHD14B,PROS1,TMEM204,EWSR1,B9D2,VMP1,SLC19A2,CBR4,MSMP,HSPA8,EMP3,CHMP2A,CCDC25,TES,BECN1,LMNB1,GMPPB,CALHM2,ADO,RPLP0,IL10,UBE2V2,FUT9,PHYH,NTN4,RTKN,COMMD8,CSNK1A1,ITGA6,PELP1,IFNA10,DEFB114,MT1M,TFE3,SH3GLB1,THTPA,PREPL,RNF113A,EFNB1,GOLGA7B,TSPO2,EIF4E,TRIM5,TMSB4X,COX4I2,CDKN2C,LHFPL4,BLOC1S2,SNCG,SNAPC3,DDX39A,RAB40AL,AKAP12,IGBP1,SSU72,FABP7,BCAP29,ZBTB17,B3GALNT1,CREB3L4,EIF3K,CD274,NAT2,KHDC1,SPECC1L,BZW2,OR10G9,TSPAN5,RINT1,IFRD2,ZNF501,CEP97,POR,ST3GAL5,SLC32A1,PARP11,TAS2R40,LRP6,PYROXD2,MRPS21,LCA5,STK24,RAC2,PRKAB1,UQCRH,DPEP1,MTHFD2L,IRF3,KLC2,PAX9,STXBP1,PCMTD2,CSNK1A1L,SOX2,ST3GAL1,IL18,DERL1,KLK6,FKTN,DNAJC3,RNASEH1,TMED7,SERINC3,SLC41A3,TSN,STOML3,STAU1,PCDHB1,ABHD4,BRCA1,RBM7,TRAF2,KCNK13,CDK4,NPR2,DPY30,NR1I2,CNNM4,STMN2,RGS2,DUSP19,NME1,ADPRH,PDHA1,NOS1AP,BCL10,KCNMA1,MBD5,LAMB2,SLC13A5,CLDN4,RAB3D,CXCL3,GTF2B,RUVBL1,SDF2L1,GIT2,NKIRAS1,ACAT1,ZNF287,KDM4B,TMEM184B,CDC42SE2,ACBD7,FAM98A,RPLP2,TRIM54,HTR1F,RDH10,PDCD4,LDOC1,GPAM,CREBBP,PRPF19,GREM2,TGIF2,GPX6,POPDC2,FAM162A,CTDSP1,CCNB1,NDUFAF4,AKAP14,CRYBB2,TFCP2,CLDN1,ABHD6,METTL2A,UHMK1,LCP2,CRTAP,ERH,ALKBH5,ADIPOQ,ANKRA2,MBL2,MAP3K11,JPH4,AMIGO1,TOR2A,PTS,METTL14,VAMP5,EDEM1,GNG2,CSGALNACT1,R3HCC1,SAT1,RMI2,COL1A2,SLC35D1,SMU1,TMEM123,DSTYK,ZBTB5,AIF1L,ZC3H7A,IPO8,TMSB10,CIDEB,ATAT1,ARMC7,HSP90AB1,POLE4,GPHN,ISG20L2,FCN2,RER1,SFRP4,RGS7BP,CDKN2AIP,CSRNP1,ATG4A,SYP,ZNF862,MRPS23,FUNDC2,GBE1,CHGA,TCF23,TMX3,HTR5A,DNAJC22,EIF2B3,BCL7B,TOM1,GPR65,SEC61B,MYO6,NDUFS8,CYP2C18,NKX3-1,F9,GCNT3,TOP1,TMEM144,NRSN2,GPR137,APOO,BCS1L,SNX17 |
| 8.321e-24 | -53.14 | negative regulation of cellular metabolic process | biological process | GO:0031324 | 2998 | 1116 | 18204 | 5365 |
ALKBH4,APOBEC3C,MIR129-2,CCAR2,MIR592,MALSU1,FBXW7,MIR616,MAGEB1,POLDIP2,HDAC6,SGF29,MIR208B,NOG,PRR5L,ACVR1B,HNRNPL,TMBIM6,NR1I3,ASB1,RASD1,CNOT6L,DUSP1,TNRC6C,MAGEA4,MIR101-1,NIF3L1,VSIR,MIR363,XRCC5,TBK1,MIR632,FEZ1,MIR32,PPIF,ZBTB39,PIAS1,MIR373,MIR183,RPS13,G6PD,H2AC1,APOBEC3A,C1D,MRPL13,MIR16-1,POU1F1,RBM42,CIART,PDE2A,IGF2BP1,NPPC,PHF23,PSMC5,MIR7-1,DUSP6,H2AC25,MRTO4,MIR939,PIK3CG,THY1,HNRNPA2B1,MIR140,FASLG,INSIG2,RNF41,EID1,ELK3,MIR572,MIR891B,H1-3,CCDC85B,KLF3,MAGOHB,MIR15A,MIR143,ETV6,PDCD4,ROCK1,MIR139,SUPT4H1,STAU1,CBX7,APEX1,PIK3CA,CRYM,MIR493,ELK4,SOX14,H2AJ,MIR218-1,NIBAN2,MIR301B,MIR922,YWHAZ,MAGED4B,FOXP2,MIR30E,RAN,NR2E1,MIR944,CUL3,NR0B1,MIR24-2,NF2,CEP85,TIMP1,MIR874,CCAR1,SATB1,CTSA,MTA2,IL23A,VEGFA,MIR652,MIR194-2,EIF3E,MIR298,NUDT16,MIR455,MIR532,PPM1B,NSMCE3,MIR769,MIR137,MIR211,MIR595,DUSP26,TLR6,EXOSC8,MIR569,AKT1,SIAH2,TGFB3,IL1B,MIR182,MIR374A,CLP1,PPP3CA,INPP5E,MXI1,MT3,MIR877,MIR345,CCND3,RBBP4,TNFAIP3,MAX,GSTP1,VDR,BAK1,TXN,TCF23,MIR331,MIR675,SIRT7,MIR639,SKIC8,CALR,PTRH2,SAP30,IGF1,MIR604,SPRED1,PPP1R11,CNOT2,UBE2D1,AR,MIR492,CNR1,PAIP2,PHF1,CCND1,HIRA,MIRLET7B,IL2,MIR130A,TRIM63,PAK2,PID1,RPL13A,MET,MIR1251,TERC,MIR631,MIR320A,MIR448,MIR10B,CDK5RAP3,MIR450B,ACP5,NR1H2,MIR125A,MIR187,TCEAL1,E4F1,TSG101,PHC1,MIR607,SMARCE1,DAPK3,KLHL25,MIR130B,PRNP,SPRY1,LMNB1,MIR589,CD274,FOXP3,AKT3,HMX1,ERRFI1,MIR1224,PPP2CB,COPS2,GNAQ,LSM5,BAHD1,PYDC2,SOX21,CHMP1A,BAX,MIR379,EIF4E,ZBTB2,TP53INP1,ID4,IL6,ERLIN2,MAGEC2,MACIR,MIR223,NKX3-2,CDC73,IFNA2,MIR96,DNAJC3,FABP4,MIR648,NACC2,SFN,DNAJB6,PPP2R5A,E2F6,SMG8,ZBTB16,ZNF24,MIR148A,MIR580,RPL10,MCL1,MIR383,ORMDL1,KCNIP3,PLCB1,MIR196B,MIRLET7D,HDAC3,MIR887,MIR454,UCN,HP,ANXA4,MIR423,MIR577,MIR204,ZBTB33,FOXS1,NMI,TXNIP,WNT10B,MAD2L2,PAX6,PKIA,DUSP10,MIR628,KDM2A,MIR98,EMILIN1,MIR649,RNF5,FBP1,MIR1296,ITGB8,HINFP,PFDN5,HFE,MIR615,BCL6,CDK5,HEXIM2,ORMDL3,HMG20A,DNAJC10,PDE12,ING1,PHB1,CDK8,MIR191,MIR624,ATP1A1,MIR1298,CX3CL1,BRMS1L,RBPJ,NAB2,XCL1,MUL1,HMGA1,CAMK2N1,TWSG1,MIR9-2,SHMT1,TNF,PDCD1LG2,MIR552,CLDN3,CASC3,H1-5,FOXC2,NLRP3,MIR764,PAIP2B,PPM1D,GJA1,ZHX3,H2AB1,MIR17,MIR214,YWHAB,MIR502,TYMS,RB1,MIR301A,CITED1,PHF12,MIR338,EID2,NAB1,MIR105-1,NDN,TMEM39A,SDR16C5,MIR16-2,MDFI,CDKN1A,RIOX2,SUPT5H,LSM14A,TLR4,APLNR,ZBED3,KLF4,PAX9,MIR147A,TGIF2LX,PTPN1,HSPA8,CNOT8,MIR99B,ITGAV,MIR26B,SAP18,PCGF2,TIMP4,NCBP2,DDX5,LEPR,ZC3H7A,PCGF6,MIR1-1,MAP3K3,MIR583,MAEL,TP53,HENMT1,SDCBP,MIR188,MIR671,MDM2,APOBEC3H,RBM15B,MIR212,SCFD1,MIR503,MIR218-2,SUV39H1,MIR193B,SUFU,HOMER3,KLHL22,HELLS,IMPACT,CDKN1B,LHX2,DROSHA,MIR1249,MIR198,PIWIL1,RPS26,MIR195,IFRD2,CYP27B1,ZBTB14,RNF139,MIR335,ZNF692,LGALS3,WDR6,MIR638,ZNF668,C9orf72,BHLHE40,MBD3,MIR1226,HAND2,DDX4,ZNF345,SRSF7,HCFC2,CCR7,THAP7,STAT6,RNF8,DHX9,MIR600,DKK1,MIR25,MIR367,MIR517B,MIR30D,TLE1,LSM2,MIR9-1,OTUD7B,RERE,RLIM,MIR370,DUSP3,MIR192,MIR597,LRP3,MIR449B,MIR346,IKZF5,BANF1,DLG1,MIR215,CNOT6,DCAF5,IGBP1,SNAI2,ZCCHC7,BECN1,MIR489,DICER1,FIS1,MIR429,CBL,NDFIP1,SOX9,IL1R2,DHRS7B,CSNK2A1,CPEB1,EXOSC4,MIR551B,GHRL,RGN,MIR488,MIR558,TOB2,MIR936,SAP30L,IRF8,PRMT2,CCR1,HDAC5,MIR511,MIR339,PELO,TRIM29,NR1I2,KDM1A,CD200R1,TSN,EIF4EBP2,MIR29C,FKBP1A,SRSF12,KLF12,MIR1225,PARD6A,ETFBKMT,CSF2,BTN2A2,BARX2,IRF3,HEY2,IL12A,MIR132,LILRB1,ID1,HNF1B,CCL3,MIF,FZR1,PPIA,DUSP19,AGO1,CRYAB,NUPR1,MIR484,MIR761,TIMP3,FLCN,MIR302B,SFRP1,MAGEH1,RTRAF,MOSPD1,EPHA4,MIR200A,MIR605,RPS14,MIR7-2,MIR942,MIR3173,RORB,ARPP19,SCML1,NKRF,DGCR8,MIR146A,MIR149,CD46,IGFBP3,MIR662,NPTN,MIR504,IL4,THAP1,BEND6,IL20RB,SOCS5,MIR150,LANCL2,DKK3,RUVBL2,ING2,SWAP70,MIR452,MIR760,ZBTB17,FURIN,CHID1,MIR101-2,MIR876,CPTP,MIR661,TYROBP,MIR653,STK38,STAP1,ATF3,NFKBIL1,NKX3-1,FCGR2B,MACROH2A2,MIR924,MIR599,PCGF3,KLF10,MIR205,MIR23B,SETD5,ELOC,IRF2BP1,TUSC2,HNRNPD,EIF4A3,MIR920,PNRC1,SERPINB1,SMAD3,MIR24-1,DUSP22,NR2F6,SCML2,MAGEB10,MIR378A,TRIB1,PLAGL1,H2AZ2,SFTPD,GADD45A,TRAF6,CAMK2N2,ZBTB25,MIR222,MIR181D,NUDT12,MIR1180,CD38,CD2AP,MIR802,GSKIP,MIR937,PABPC1,EIF2S1,ARG2,TESK1,LRIF1,TERT,MIR491,SNAI3,NFKB1,MIR141,PML,IRF2BPL,PSPC1,HCLS1,ATF4,CD200,MIR601,HNRNPK,LEP,SQSTM1,POLR2G,ZNF175,PHB2,HEXIM1,MIR148B,SRC,ADRA1A,MIR34C,ANGPT1,PIWIL3,SMARCA5,PPID,MIR765,MTMR2,NRDE2,SRGN,MIR135B,LGR4,USP30,HOXB8,MEF2A,PRKRA,IFNG,TAB2,MIR7-3,BIRC5,TENT2,MIR34B,DYNLL1,ZBTB5,MIR873,CTNNBIP1,METTL14,EIF4EBP3,MIR153-1,TCEAL7,MYT1L,TLR8,CIPC,IFI16,MIR296,NTRK3,MIR551A,CCDC3,MIR618,MIR563,ITM2B,IRF1,TRIM3,BRMS1,INSM2,GTF2IRD1,MIR625,MIR100,MIR29A,EDC3,LYPLA1,MIR542,SRSF4,UBASH3B,EXOSC3,MIR549A,DRAP1,MIR181C,BMPR1A,MECP2,MIRLET7I,PRMT6,DNAJB4,SOX3,SELENOS,SMAD4,GRB10,MIR9-3,RNF128,LSM4,MIR99A,PRMT5,H2AC6,MIR92B,NOP53,MIR136,MIR938,EID2B,MIR1271,ZMYND11,LMNA,MIR578,GMNN,TSNAX,ANXA7,H2AC7,SP2,CTNNB1,HYAL2,BACH1,MIR1227,OVOL1,EP300,MIR384,DR1,MAGOH,PDCD10,MIR497,TRIM24,SLC8A1,CRKL,NCOA5,PHF21A,CTDSP1,MIR221,MIR155,MIR206,EIF2AK2,H2AC4,MIR643,CREBZF,MIR377,AATF,LMO4,SNX12,DEFB114,SMCHD1,CD34,DEDD,PPP1R8,GSK3A,CRY1,PKIB,STAT1,BST2,MIR573,USP3,LRP6,MIR500A,MAF1,PTEN,MCPH1,PPARA,MIR10A,MTA3,ZNF263,MIR449A,ENO1,LDLR,CBX3,MIR885,DMAP1,VDAC1,MIR186,MORC2,JUN,MIR107,USP2,ERP29,MIR633,RFX5,CSK,MIR1-2,LDB2,PCBP4,MIR185,IL12B,FOXP1,THRAP3,MIR190A,YWHAG,INHA,MIR30B,MIR21,MIR519D,CPNE1,MIR375,ANAPC2,WDR82,MSX2,SYNCRIP,TIA1,RGCC,ABCC2,MIR651,MIR330,MIR548C,SRSF10,MIR33B,MIR197,DXO,TCF21,POU5F1,FOXD3,MIR210,BAP1,MIR593,CD36,MIR129-1,RRAGB,PC,LYAR,IFI27,SIN3A,PYCARD,HRAS,MIR23A,ZNF304,MIR361,AGER,MIR875,GABPA,EPHA2,RGS2,HMGB1,CORO1C,MIR495,CXXC5,FOXP4,ETF1,TRIM6,RPS3,PPP1R1B,CDKN2C,NKX6-2,TAGLN3,NMBR,CX3CR1,MIR145,MSX1,CBX5,SRSF2,STN1,MIR640,FERD3L,IL10,ROCK2,H2AZ1,YAF2,MIR567,MIR611,DDRGK1,MIR636,RBBP7,MIR505,LBH,ADIPOQ,MIR657,MIR1277,ACOT8,MIR581,CGGBP1,F2,MIRLET7C,EIF4E2,STK38L,XAF1,LDB1,TFDP2,DIS3L,DAP,MIR424,ADNP,FBXW11,SPINDOC,ZBTB45,H2AX,APOBEC3B,INPPL1,PSMD10,MIR586,POLE3,NONO,CDK6,DNAJC2,DDIT3,TRIM27,SMG9,ENC1,MIR590,PTPN11,SIX5,PIWIL4,MIR155HG,NKAP,FGFR1,MIR340,ATXN1L,PTPRQ,HELT,MIR34A,UBE2D3,MIR609,IL13,MIR770,MITF,VPS72,ZNF451,MIR216A,IDO1,FKBP8,MIR133B,RRAGA,TAF7,CXCL8,PTGER4,MIR626,MIR30A,RPL23,PAQR3,CYP7A1,MIDEAS,PPARG,MIR106A,SESN2,MIR711,GPNMB,SLA2,PGR,BTG2,TSPO,ZBTB6,UFD1,DCP2,MIR193A,EZH1,MIR1262,UPF3B,EZH2,MIR554,CHRNA7,ESR2,YTHDF2,MIRLET7G,IKBKB,EGR1,MIR422A,MIR934,GAPDH,CNOT7,MKKS,LSM6,RAD21,MIR28,NR4A2,EPO,CREBBP,PROX1,MTDH,ZBTB18,GREM1,MIR940,MIR147B,ZNF177,PIWIL2,MIR152,DDIT4,FMO1,HSBP1,DYRK1A,IRF2,GCLC,TRIM37,SOX2,PTPN22,SPRED2,ZBTB38,MXD1,NCK1,RING1,SEC22B,PCNA,MIR612,CRYBA1,TGFB2,CHP1,MIR144,DBNDD1,NOTCH2,PICALM,MAFG,PYM1,TRIM22,MIR656,CIRBP,TADA3,MIR20A,SUMO1,TWIST2,OAS1,HNRNPC,ZNF174,SHC1,CTBP1,MIR1260B,MIR708,MACROH2A1,XPO5,ZBTB26,SMAD1,MIR425,ATP2B4,MIR200C,NLRP6,IRF7,CTDSP2,CDK5R1,MAGED2,H2AC13,MIR557,SMAD5,SOCS4,NFIL3,TGIF2,EED,INPP5K,MIR194-1,RPS6KA4,OSR2,MOV10,CDK1,SNIP1,APLN,MIR105-2,MIR190B,CD83,APOBEC3D,MIR556,DAPK1,MIR142,APOBEC3G,MIR490,HSPB1,TDRD7,PRDX3,MIR184,MYC,MIR553,CREB1,MIR126,IER3,HNRNPA1,MIR216B,DLX1,WWP2,MIR106B,FMO2,ITM2A,AP2A1,ZBTB42,HBEGF,ARB2A,LILRB4,PSEN1,MTM1,UBE2I,ZGLP1,APOBEC3F,MIR324,SNRNP70,ZHX1,MIR342,SMAD2,WWP1,MIR31,BRCA1,PKIG,MIR208A,GFI1,CNKSR3,ZMPSTE24,RUNX1,CYP2D6,ZMYM2,MEF2C,BEND5,CAV3,FKBP1B,ERLIN1,VGLL4,CDKN2D,CD28,CBFB,RBFOX2,SMG5,RC3H2,MEPCE,TRIM11,IFNB1,CAV1,SOCS3,RBBP8 |
| 9.060e-24 | -53.06 | HSPA1A (heat shock protein family A (Hsp70) member 1A) | protein interactions | 3303 | 1423 | 568 | 19454 | 5460 |
GSTM3,TBC1D5,DIS3L,FKBP4,HSPB1,YWHAB,FABP5,TNIK,SDC4,CORO1C,S100A8,MAGED2,HEBP1,PAIP1,PGR,DYNC1I2,ELK1,HMG20A,MAX,ERRFI1,SUPT5H,RANBP1,ISG15,CSTF2T,MSX2,METTL21A,MTA2,ZRANB2,CRKL,CCT8,PABPC1,DNAJB4,RUVBL2,RTCB,RPL28,HNRNPDL,POLDIP3,TBCE,HMGCS1,LAMTOR1,COMMD9,CHTOP,DNAJB6,EFHD2,SF3B4,ANAPC2,PSMD4,TRIM29,PSMD6,TOM1L1,PPP5C,RPL27A,PAFAH1B1,PLAA,ADSS2,PAK2,CTBP1,PIH1D1,RFC4,FOS,FLYWCH2,HSPA8,HDAC5,AKAP1,UBE2D3,PITHD1,STAU1,KARS1,PGAM1,RBM17,DNAJB2,COPS5,MZT2B,TUBG1,BECN1,RPL10A,STT3A,SYNCRIP,ARMC1,MCL1,TMPO,SNAP29,UBL4A,RRM1,IPO8,RAP1A,ACTR1A,H2AX,WBP11,TFCP2,TAB2,RNF8,PSMC3,SNIP1,NAE1,ILDR1,SLC25A11,MRPS18B,SLC16A1,ERO1A,IDH1,REXO2,CAPZA1,MAT2A,PTPN11,SLC6A4,EIF3G,RC3H2,ATP1A1,RPS3,ZBTB33,ZNF330,MRPS28,MOB4,PSMC5,QSER1,SGTA,PRKCE,ADRM1,MYG1,ROCK1,SMURF1,BCCIP,SRC,CAPN1,GABRA1,CFTR,RPA2,RPRD1B,H2BC11,PRKCA,UBE2M,ACACA,APMAP,THUMPD1,RNF113A,PRDX6,RAB9A,UBE2K,NAPG,KDM1A,ZC3H15,MARS1,HSPA5,UBXN6,PRPF19,CLPX,STOML2,RAP2B,MAP3K14,PSMD10,AHSA1,NQO1,RPL23,CBFB,PHB1,IGBP1,GJA1,COPS2,NOP58,CCAR2,SNX1,ATXN10,NTMT1,RAB11B,MARCKSL1,TPD52,FEN1,TXNRD1,ACO1,SNCB,EZH2,CFAP36,EIF1AX,RPS24,UBE3A,LASP1,G3BP1,ETFA,PPWD1,MCM6,RFC2,CUL3,GRB10,CUL2,RFC5,GALE,LMNB1,FAU,RNF208,PELO,RAN,AP2M1,FOXP3,MB21D2,MAD2L1,RPL19,GNB1,ALKBH3,PPP1CB,RNF7,MCRIP2,WBP2,CRY1,NUP50,TTC1,HADHA,ATAD1,NSFL1C,FBXL4,NFKB1,CDC37L1,TLE1,LRRC40,ESYT1,DNAJC7,AIFM1,H2AZ1,HSD17B11,ALCAM,KCTD15,MAPRE2,ATP5PD,G6PD,CAV1,CCDC47,EEF1A1,GGCT,UAP1,ILF2,APEH,PDLIM4,DLG1,ZC3H11A,HSD17B10,PC,HINT1,CTNNBL1,TOM1,HSPE1,THRAP3,OLA1,PRDX4,EIF3E,MSH6,CSK,AAMDC,PYCR2,ATP5F1A,RUNX1,USP14,TUFM,AR,NONO,CHORDC1,TXNIP,EPHA2,STK11,OPTN,PELP1,STUB1,SMAP2,SCAMP2,EIF4A3,DTYMK,RPS20,TRIM24,PTEN,CFAP298,LDHA,TXN,RAB14,RPL13A,YES1,TECR,RPL22,SAP30BP,PSMC4,MYL12B,EDF1,RBMS2,JUP,RPLP0,OXSR1,MME,MAVS,PPP1R2,EIF5B,SMC4,NUCKS1,NHP2,LAMP2,WWP2,YWHAH,YWHAG,CTNNB1,DDRGK1,DDX1,MAGOH,SIN3A,RAB35,CD63,SWAP70,ANXA4,DUSP6,HNRNPL,RPS10,SUMO2,SNRPA1,SNRPD3,HSP90AB1,CCT7,EEF2,RPS7,PTRH2,RPS23,HGS,CSTPP1,ABCF1,EWSR1,HNRNPF,RUVBL1,APOBEC3B,MYC,HNRNPAB,HNRNPC,PSMA4,BTF3,BAG3,CCT2,PSMD14,S100A11,ATG3,RPS26,RCL1,H1-1,MDH1,ZMYM2,TAGLN2,MATR3,STAT1,RPL10,APEX1,MTF1,BET1,PSMB3,MRPL12,MAP2K1,EIF4B,NANP,PEBP1,SF3B1,UFL1,SRSF2,EEF1G,ADRB2,PACSIN3,LYPLA2,ELOC,GAPDH,SHC1,H2AC4,MAP4,SSBP1,METAP1,ITGA6,UBE2N,MTAP,CAND1,PLG,LMAN1,MYL12A,MVD,KBTBD4,INSIG2,TP53,ESS2,CER1,CBX3,CAPN2,GNAI3,MAP1B,PSME1,DHX9,NEDD8,PDE12,PSMA5,RDH11,AKT1,TRIM32,PSMB2,CARS1,NUDT4,CFL1,DNAJC5,ST13,UBE2H,SF3B6,NECTIN2,MID1IP1,GNAO1,PITPNB,SRP54,MACROH2A1,CTSB,EIF4H,IRF2BP1,CDC20,CDC42,SSR1,DYRK2,BAP1,DDX46,RPL27,PML,PGK1,ARFIP1,GRPEL1,UGP2,HMGA1,PDIA3,VPS26A,HNRNPA1,CDK5RAP3,NAB2,HNRNPD,DCAF11,SLC20A1,PDAP1,RPL9,MAP1LC3A,HYPK,SRSF10,PPIA,HSBP1,DHX15,RAF1,RBM12,ARFGAP1,NAA15,PPP2R1A,ACTN4,SKA3,GDI2,NME1,PPID,PRKAG1,RPS11,JPT2,SNRPE,ZYX,HSPD1,SCYL2,NUDT5,HNRNPA2B1,SLC2A8,BAG2,UFM1,PSMD12,RAD21,RAB11A,JPT1,MAP3K21,IRF1,YWHAZ,HSP90AA1,PAXX,SCFD1,BAX,RPS5,ILK,RMI1,BAD,SNRPD2,SEC61B,RPS9,PRDX2,TUBB,ACTB,TAB1,GPR37,USP5,ERH,CLIC4,ACTL6A,DET1,NUDT3,CDKN1A,IRF2BPL,SLC25A3,DNAJC3,SNRK,CFDP1,TERT,UCHL3,YTHDF1,PYGB,AZGP1,DAG1,KIAA1143,UPK1A,CNN3,RPL12,PSMB1,RPL35A,DCUN1D1,TOMM70,CDK9,CWC15,MRPS23,FBP1,NDUFA2,CCT5,MAP2K3,EXOSC8,SOX9,MAGEA4,FAF1,PPP1R12A,TCOF1,RNF167,TMED1,RPL23A,HUWE1,PTGES3,CNTNAP1,BRAP,RPL26,GMNN,ZSWIM7,ARFGAP3,MAPRE1,CCNF,GAB1,ENO1,EIF2AK2,CTTN,ZBTB18,NDN,SH3BGRL,CTTNBP2NL,VIRMA,GNAI2,SF3A1,PIP5K1A,ARHGAP1,SEC22B,SYNRG,CZIB,METTL14,RARS1,OR10A4,KRT7,CARHSP1,HAUS2,WTAP,RPA3,SOD1,DVL2,IDH3A,HMCES,RTN4,YKT6,PDHB,FBXW7,CHMP2B,PIAS1,VPS28 |
| 9.418e-24 | -53.02 | medulla | COSMIC cancer mutations | medulla | 14778 | 4432 | 16828 | 4835 |
EIF4EBP2,OR2A2,SV2B,HPCA,SOST,TCP11L1,NDUFAF2,GPR37L1,SNAPC1,SNTA1,GFOD1,SIVA1,H19,SPRED1,NONO,POLL,MAK16,ALDH1L1,TSSC4,NOL4,IQSEC1,FYTTD1,SIRT7,RRAGA,ETV6,TAPBPL,TNFAIP3,ABHD16B,RAP2B,DUOXA2,MTMR12,TRAF7,MMACHC,CLEC12B,SFTPD,INTS12,SOCS2,CYP2D6,CTNNB1,RAB8B,CDK6,CWF19L1,ESR2,DCAF5,ADCY3,SNRPD2,CERK,USP39,SLPI,USP38,ZNF174,PROX1,FGF13,PRKX,LSM6,ZMAT5,RTP4,SYNGR1,NAB1,ENPEP,KLF10,MPHOSPH10,MRPL47,TMEM33,S100PBP,AP3S2,SCG2,ARHGAP21,RHCG,SPINK13,FAF2,BMPR1A,SETD4,LCN6,COX7A1,FBXO9,TMED3,ACOT13,WFDC13,CCND1,RPGRIP1L,OR2W1,CPT2,CHST9,ANP32B,NDNF,AP1G2,CETN3,URM1,CACYBP,CTSK,MTAP,RAB3C,PWP2,TOLLIP,BATF,TGFB1I1,DUSP1,STX8,FAM200A,S100A10,NFYA,MRPS25,RBCK1,NFE2L1,SPATS2L,NOP58,AKR1A1,FABP5,MRGPRX4,PGAP2,CTSD,DEK,NLGN2,CYP4F8,PRKD3,SLC5A6,SPEF1,SCAMP2,CD164,CDKN3,BPGM,PPIB,ENTPD4,ARMC8,SLC35A2,ID1,PTDSS1,CYC1,POU1F1,NPTN,FCAR,CCDC42,CRYBA2,DEGS1,INPPL1,MIA2,BACH1,KIF2A,RNF187,APOBEC3C,GPR162,ZNF513,SLC7A4,ZMYND11,EXOC2,XPO1,EFHC1,SLC25A32,GJA10,THRAP3,EEF2,RNF103,CREB3,TF,INTS10,SURF4,XPO5,THOC1,ABCC5,RANGRF,NUDT19,RC3H2,ATP2C1,FATE1,DNAL4,PCDHA5,SLC20A2,UBXN10,NUBP2,PFDN6,LDHA,PRCC,GSK3A,WDR37,EIF4EBP3,ZSCAN1,SLC39A9,DHX9,FURIN,PSMD6,IL23A,GNMT,CCL25,AQP4,CREBL2,TXNIP,GLE1,SPOCK1,PHKG1,LASP1,NEK7,UTS2R,GTF2A1,WBP2,FUT8,GALE,SH3GLB2,EIF2B5,CIRBP,ENDOD1,CXXC5,TRA2B,RAB4A,SOX21,DHX16,LEAP2,HADHA,LHFPL1,HSPB1,KCNA2,B4GALT6,GXYLT1,NUDT16,PGBD2,SIPA1L1,STAMBPL1,CLDN14,ZKSCAN1,HSPE1,RPL37A,SERPINH1,MSX2,RPRML,NLE1,KRR1,SNAI3,CDC37L1,PELI3,XPOT,FRA10AC1,PDIA3,NDUFB8,APH1A,ISYNA1,NAA11,EIF1AD,STX17,LEPR,WNT7A,DFFA,IL34,RASGRP2,LPXN,ST13,POLR2I,CD2,FBXO30,TIGD7,WWP2,RABAC1,ACAA2,RAP1A,UCKL1,HBB,FGF17,NEDD8,CXCR1,PTCRA,TRMT6,NDUFA5,CCL21,KCND2,BRI3,HEXA,ADAT1,TMED1,RBM23,BRMS1,CD3G,CDKL2,GAS8,KIF1C,CHRNA7,TAC1,LMBR1L,IGFBP4,NPVF,AKR1C2,SPATA2L,TBCE,NQO1,IPP,DHRS3,DEFB116,TNFAIP8L2,NDST1,KTI12,SMAP2,CDCA3,RAB3B,AZIN1,PSME2,HBE1,INO80C,AZGP1,ABCB1,FGF1,JAK1,LBH,MLF1,GTF2E2,MAGOH,CCL19,NKX3-2,TBC1D10C,ZNF24,TMEM215,FBXO42,SERPINB10,TSEN54,ATP6V1G1,WDR77,MTPN,MEST,FZD4,AAMP,ZCCHC10,SYN3,GPBP1L1,MX2,MFSD6L,LYG2,ROPN1B,VRK1,PGK1,HEBP1,ALKBH4,SLC7A9,MYH2,SNAP91,DNAJC5,TMIGD1,LHX2,CDC73,ZYX,UBAP1,CYP27A1,DYNC1I2,S100A6,BTF3,MMP9,SUPT7L,JOSD1,AFTPH,LSM3,RS1,KIT,PIWIL4,CSNK2A1,KPNA1,RARRES2,CTNNBIP1,GNG7,ATF4,GSTO2,KBTBD2,PRPF4,ARMCX5,ZNF593,RAB18,IDH2,FKBP14,AGER,CD58,IMPACT,SBK2,SORD,PSMB5,MCOLN1,CCT5,ENPP4,ANAPC2,FBXO32,AGK,PYGM,SHC1,FGFR1,CAMK2N1,HCRT,CD200R1,CRYGB,PPP3CA,KCNJ11,FAM89B,RCVRN,PEX3,CCDC127,SRP54,TMX4,BUD31,CAMK2G,PRMT2,CIB3,TACR3,TUBG1,RPL15,CACNB4,GHITM,SCFD1,TTC4,CCDC47,TRAPPC1,CLDN11,RABL2B,NIPA2,FAM199X,LRP12,NPY2R,RNASET2,SLC35E3,SPTAN1,RFX4,FRMD8,ADRB1,PKNOX1,ZDHHC14,RBM17,PCDHB8,HEY2,ARMCX2,SIX5,TRIM21,ACTA2,PPARG,GALNT12,ARFIP1,SPR,SETD5,HNRNPC,PTPN1,TRIM37,HECW1,ZBTB38,NFIL3,PGS1,SLC25A21,RBBP7,RMND5B,TLR9,SNX20,WDR38,FIBIN,L1CAM,AKT1,DLX1,FGD2,APEH,COMTD1,FNDC8,DKK3,IL20RB,SF3B4,DPP10,PRRC2A,CRABP2,CDO1,PPIL4,RAB11A,CCNI,UST,PFDN5,EXOC8,TOM1L2,GNRHR2,LYAR,B9D1,NUDT3,CNP,RND3,CCDC69,PSMA3,AK2,SOCS5,GALNT1,GSTO1,TMEM156,MDM2,MGP,EHBP1,MRPL13,GPR89A,EFCAB7,EXOSC1,ZMPSTE24,E2F6,GFM2,GDI2,MRPL23,KLK9,PLA2G5,DOK4,ARHGAP1,RNF141,KLHDC8B,TRIM32,PRIM2,SNRNP27,CD99L2,SDR42E1,PDIA6,UBR7,SLC25A31,ZNF671,SLC17A5,LIG3,RPS14,LYPLA1,MEAF6,UGCG,ZNF207,EDF1,TMEM219,ATP6V0B,TMUB1,TRIM3,C1QC,POLR3H,CCR6,TAAR1,ZMYND19,SLAMF9,XAGE5,ZNF397,APOBEC3A,SEC14L1,ZNF319,ID4,NRP1,NCKAP1,CDK5R1,CNIH4,GLUL,LMO4,CLU,KIAA0232,ATPAF2,CASK,GAL3ST1,LTBR,ELMO1,GRPEL1,TCP11L2,PRPSAP1,GABARAP,FGFR1OP2,ARMCX1,UBE2A,UBE2D3,ATP6V0E1,CCT2,NHP2,NAIF1,TRIM23,ING1,STRBP,IRF1,SLC38A9,IL15RA,PPP1R2,FAM78A,MIOS,RMND1,SLC35A1,DHRS4,MEF2A,IMMP2L,RAG1,ENY2,KLK3,SLC30A5,SNAPIN,ZNF304,MRPL24,MRPL50,NCR3,ITK,EIF4H,FAM8A1,SWAP70,MYL12A,CYP39A1,HSD11B1,GNRH2,CHDH,CTNNBL1,GRM2,CYP11B1,IDH3B,SENP5,JAKMIP1,GPAA1,TLR3,ZBTB5,AIF1L,ZC3H7A,DSTYK,TMEM123,ATAT1,ARMC7,CIDEB,IPO8,TMSB10,ISG20L2,GPHN,POLE4,HSP90AB1,FUNDC2,MRPS23,CSRNP1,ZNF862,ATG4A,SYP,SFRP4,CDKN2AIP,RGS7BP,FCN2,RER1,EIF2B3,DNAJC22,TMX3,HTR5A,TCF23,GBE1,CHGA,SEC61B,GPR65,BCL7B,TOM1,GCNT3,NKX3-1,F9,CYP2C18,NDUFS8,MYO6,APOO,SNX17,BCS1L,GPR137,NRSN2,TOP1,TMEM144,GIT2,NKIRAS1,GTF2B,CXCL3,SDF2L1,RUVBL1,RAB3D,SLC13A5,LAMB2,CLDN4,KDM4B,TMEM184B,ZNF287,ACAT1,TRIM54,RPLP2,CDC42SE2,FAM98A,ACBD7,GPX6,POPDC2,GREM2,TGIF2,RDH10,PRPF19,CREBBP,LDOC1,PDCD4,GPAM,HTR1F,METTL2A,ABHD6,CLDN1,TFCP2,NDUFAF4,AKAP14,CRYBB2,FAM162A,CCNB1,CTDSP1,ANKRA2,ADIPOQ,ALKBH5,ERH,UHMK1,CRTAP,LCP2,VAMP5,METTL14,GNG2,EDEM1,AMIGO1,JPH4,TOR2A,PTS,MBL2,MAP3K11,SLC35D1,SMU1,RMI2,COL1A2,SAT1,R3HCC1,CSGALNACT1,PARP11,SLC32A1,POR,ST3GAL5,IFRD2,CEP97,ZNF501,RAC2,LCA5,STK24,MRPS21,PYROXD2,TAS2R40,LRP6,PCMTD2,STXBP1,KLC2,PAX9,MTHFD2L,IRF3,UQCRH,DPEP1,PRKAB1,IL18,DERL1,ST3GAL1,SOX2,CSNK1A1L,SERINC3,SLC41A3,FKTN,KLK6,TMED7,DNAJC3,RNASEH1,STAU1,STOML3,TSN,DPY30,NR1I2,CNNM4,NPR2,CDK4,KCNK13,RBM7,TRAF2,ABHD4,PCDHB1,BRCA1,KCNMA1,BCL10,NOS1AP,MBD5,ADPRH,PDHA1,DUSP19,NME1,STMN2,RGS2,ABHD14B,MRPS16,EED,ZNF592,MTRF1,CIB2,MRFAP1L1,TRIM24,TGFB3,ACSL4,YAF2,ELP3,EWSR1,B9D2,TMEM204,PROS1,CHMP2A,EMP3,HSPA8,MSMP,CBR4,SLC19A2,VMP1,CALHM2,ADO,GMPPB,LMNB1,BECN1,TES,CCDC25,RTKN,NTN4,PHYH,FUT9,IL10,UBE2V2,RPLP0,GOLGA7B,TSPO2,THTPA,SH3GLB1,PREPL,EFNB1,RNF113A,DEFB114,MT1M,IFNA10,TFE3,COMMD8,PELP1,ITGA6,CSNK1A1,RAB40AL,DDX39A,SSU72,AKAP12,IGBP1,SNCG,BLOC1S2,SNAPC3,CDKN2C,COX4I2,LHFPL4,TRIM5,EIF4E,TMSB4X,OR10G9,TSPAN5,BZW2,RINT1,NAT2,KHDC1,SPECC1L,EIF3K,B3GALNT1,CREB3L4,CD274,FABP7,ZBTB17,BCAP29,FGFBP2,EZH2,ARCN1,KCNIP3,INPP4A,AMT,RAB9B,PHYHIP,DYRK1B,FN3KRP,WIF1,ISG15,ACADSB,SNX24,STAT6,SNRPA,CMPK1,BEND5,VAMP2,CCNF,TRAPPC6B,WDR44,GPIHBP1,CTNNA1,RAB2A,SACM1L,VPS33A,CD226,CRBN,ZFP1,PDYN,B4GALT3,FOLR1,SLC6A11,RAB37,C1QL1,CSTF2T,PSRC1,FBXO25,IFI35,CAV2,TIMM10,STK38,WEE2,PNP,RAB5C,PCDH19,AP1AR,EIF4B,PPP2R1A,SMAD3,MRTO4,PTHLH,SLC25A4,TXNL1,DERL2,TIMP1,MLF2,PLEKHJ1,LYNX1,RPL23A,TMEM59,IL6ST,SLC4A8,SNIP1,UBE2D1,LY6G5C,FAM168A,ACTL6B,RGS5,INHA,RPAP2,RAB1B,HRH3,ABHD13,ZBTB45,AMY2B,NDE1,RBMX2,TDRD7,CD2BP2,HMBS,CCDC65,LDHAL6B,GK2,CDKN1A,RBFOX2,FOXN2,SLITRK2,STX18,ELSPBP1,CLIC2,MED11,SDHAF2,PPFIA3,PIWIL2,SOS2,AKIP1,GYS1,SLC23A2,ROGDI,PGM2L1,MYEF2,PNPLA8,TAF5L,MOV10,UQCR11,NGB,GLT8D1,TMEM14A,GDE1,GPX5,PCGF3,CDH8,CPSF2,FLYWCH2,GRIA2,LRRC24,MRGPRX2,DDX4,CAB39,LIX1,KLK5,ZCCHC9,SLC43A2,TMEM91,B3GNT2,HIGD2A,TEX12,TOP3B,RPL6,TUSC3,ADAMTS1,CXCL14,CLDN8,BNIP3L,SLC7A14,DDX42,ATP1A2,PXMP2,MT2A,PPP1R16A,CYB561D2,GMPPA,PGR,HAND2,BRD9,POLR3B,NPY5R,CXCR4,HSPA14,DLG4,GTF2F2,KIAA1191,CCL17,KCNH1,RNF122,KIAA0408,SERPINA5,CREB1,BICD2,TMEM177,FMO2,SQSTM1,GLIPR1,RPP25,RBM12,RAN,ACTR2,FOXS1,PTRH2,TMEM203,TAS2R5,CRYBB3,TMEM164,SYNJ2BP,ACP6,KCNK10,SLCO1A2,TMCC2,SELENOS,ZNF609,WDR3,GJB2,MANSC1,PLEKHA8,KRT7,TMEM106C,SRP14,GCA,ZNF576,ISCA2,RABL3,UPF3B,EHD1,FCHO2,CHST1,MPV17,TRAM2,PPP1CB,SESN2,PLAGL1,TRAM1L1,RFXANK,KLHL15,SPTBN1,TNRC6C,RNASEL,CHI3L1,UTP23,TOMM40L,EIF3J,FERMT2,GNPNAT1,GIMAP2,DNAJC8,PPDPF,TNFSF18,FAM107A,RNF167,CRYGD,RAB33A,CCR3,ZNF687,SUMO3,PTGER1,SFT2D2,RAB23,CMAS,WWP1,CBLN4,RHOJ,S100A8,HIRA,CD47,JUN,IFNG,TMEM50B,ATP6V1C1,RCBTB1,GGCT,HNRNPA2B1,MAPK1IP1L,PLA2G15,OR2A25,FANCG,STX6,CCL8,RB1CC1,SLC35E1,CAPZA2,RFTN2,TPPP,PPID,YPEL5,DYRK2,FOS,CLDN22,EGLN3,RPL26,POMP,RIOK2,MRPS28,HNRNPK,PRKAG1,NFKB1,MAFG,SCD5,ACAP2,LHFPL2,NEUROD2,METTL15,PGRMC1,PTK7,GPR171,DHX38,LGALS8,COX8A,TMEM147,USP8,HTRA2,NDUFAB1,SNAP29,JAGN1,TYW5,CBLN2,NUDT12,RPL27A,IL1A,BCL7C,THBD,PPFIA2,CNDP2,FBXW11,CINP,DNTTIP1,LRRC3,HR,ARPC3,DKC1,FBXO44,PCYOX1L,CREG2,PLD3,AGPAT5,CDAN1,SPRED2,PCNA,DDX23,PDE1B,PIK3R2,UBE2K,TMEM126B,NDUFS6,CTSC,HNRNPA0,CHST2,IKZF5,RHOBTB1,CD247,FZD3,RNF144B,DNAJB9,ARG2,ISX,GAMT,SIAE,GNAZ,GLRX5,RTN4,USP15,ELMOD2,FKRP,LPAR2,CNRIP1,APOBEC3G,NTRK2,GNG12,SEC22C,ZFAND2A,METAP2,MME,NRN1,MAPRE1,GNG10,SMG9,MUL1,NEGR1,FDFT1,SIT1,RPA3,MOXD1,EPHX1,ABHD5,CXCL13,CKS2,RORB,TXNDC12,RWDD3,CENPW,FRRS1,ATG4C,SNRNP48,SDHB,GFPT1,PTEN,RLIM,DEPDC1B,INO80E,UCN,CRLF3,MGAT5B,PTAR1,THAP7,UAP1,CLDN3,ADAM21,PPP1R1B,RND2,BMPR2,COMMD3,SCG3,OLFM3,RASD1,CCS,NLRP3,ILDR1,SHISAL2B,SCGB1D1,NDUFAF3,CHPF2,IER2,CNTN2,ASNSD1,NR2F6,HERC4,DKK1,PSMB1,CRIP1,ZMYM3,ILF2,BAG3,ZNF365,TOM1L1,KDELR1,KRAS,RPS16,RRM1,RBM22,PGGT1B,SLC38A7,KCNC1,MTA2,CCDC86,SUFU,MRGPRX3,FBXL19,LAPTM4A,CHCHD4,CHIC2,HINT2,NUF2,TMEM101,SLC16A1,PCDHB13,RPS27A,DAPK3,DSTN,TPD52,ELOVL7,RAPGEF5,DBT,METTL21A,G3BP1,CHAC2,POP5,PSORS1C2,MFSD5,FGFBP1,MRPL18,SLC6A6,TCF19,SLC30A7,CCDC134,PDHB,DDX46,MAT2B,MLC1,ZNF664,BBS5,XCL1,TSPAN18,RPS6KA4,GANAB,FBXL14,RHEB,DHX15,PSMD4,NPPC,RPS7,RAB27A,GRAP2,RELL2,TRIM15,MRPL11,SCLT1,DAAM1,LRRTM3,ANKRD34B,HSPA13,LMAN1,NPSR1,SLC11A2,PPP2R5E,UBB,SH2D1A,LARP4B,STX11,SERPINA1,PMP22,HENMT1,CSTF3,RPL7L1,CSGALNACT2,ST6GAL1,TOMM22,BFAR,TMEM179B,TOR3A,GLRX,CBLL1,UBA3,SRSF7,TAGLN3,STAT2,SAV1,EPCAM,PCDH17,IL22,PRR3,SNX22,SFXN2,CST11,FASTKD5,NCDN,GNAO1,MRPL34,NDUFB6,TMEM170B,TMEM117,IMP3,UBL3,AFAP1L2,TMEM30A,B3GALT1,COMMD6,KCNJ3,GNPDA1,ADAMTS10,EP300,RNF8,PEA15,HSD17B6,APOBEC3F,MAP2K1,PLCB2,LRRC3B,FPGT,FEZ1,PRDM4,MAGEH1,EIF4A2,COPS5,STAT5A,EFNA3,SNRPB,TPM3,SSR2,ELOVL1,MORC2,SOSTDC1,RIT1,GPX7,CHRNB2,PTPN4,LAMP2,NLRP9,FAM43A,RNASE1,TMEM45A,CCL2,GSTP1,LLPH,PPM1K,IFI6,AR,ASZ1,CYP2C8,METTL22,CAPN1,USP3,TGFBR2,CDNF,TNFRSF1B,HP,STOM,CTTN,CLLU1,RPL23,SPIN3,RABGGTB,FBXO7,SLC2A3,SEMA4C,IL2RA,PPAN,RCL1,PPP2CB,KLHL24,GABPA,FKBP8,CHST13,ZNRF1,SMAD1,AQP2,CLEC18A,TIMP3,PPP3R2,PRSS12,PRMT6,PMM2,TTL,VAMP8,MPDU1,TMEM70,IFIH1,NUDT7,FCGR2B,MTM1,BIRC2,RFXAP,EPS8,HOXC4,UPK1A,CHCHD6,SIAH2,CER1,POLR1B,CDCA7L,MRPL22,SS18,CD1C,UMPS,RAB19,KLHL22,MAVS,UBP1,IGF1R,CX3CR1,SLCO2B1,SOX14,PDAP1,CHMP4C,MCM4,SCNM1,DCTD,FAM177A1,STARD4,THOC2,FLOT1,DROSHA,NR2E1,ADD1,CLEC2B,CBR3,KLF1,CLPB,FEN1,VDAC1,ASB7,PRKACB,GLRX2,APOBEC3H,LANCL2,ERAS,GSTM5,MYBL2,PLEKHO1,ZNF326,CRHBP,CNOT2,CCNY,CHKB,ELF5,GPR176,PKP4,CLDN12,SCML2,VGLL4,DNAJC19,ETF1,LRRC8B,TRIM68,ATG7,PREB,NFKBIA,TUSC1,NPW,PRDX1,FAM53B,TAF10,ACBD6,RNF34,DENND2D,COPS7B,KLF4,ATP6V1A,EGFL7,TMEM59L,ACP5,HLF,SERPINC1,REG1B,GPM6B,FBXO22,SLC7A8,RFC3,DHRS13,PARL,POLR2B,TSNAX,UBIAD1,LRRC61,GTDC1,TMOD2,GNPDA2,SOBP,PTPN11,NAPA,NOTCH2,CRAT,TM4SF19,VEGFA,FAF1,IQCK,TP53INP1,DECR2,AVL9,DTWD1,SMPD2,TBC1D13,NCBP2,SOD1,ATXN10,ASTN1,REN,CCR1,HDHD3,SHOC2,PSMA1,RPL32,DDRGK1,SLC25A12,HMGCS1,AK3,CLCN6,USP16,LTB,PFDN2,TCEAL1,TMED5,HARBI1,SLC16A10,DIO1,VGLL2,SYNCRIP,TRMT112,SLC35F2,CLDN9,RPL27,PPP1R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NANP,USP14,TTC1,MMADHC,PHB2,PRPF31,BMP1,NR1H2,TMEM95,LEPROTL1,SPOPL,SYT2,TBC1D24,ST6GALNAC3,EDNRA,THY1,YWHAB,TESC,SLC25A44,ZNF692,CDSN,SESN3,ZCCHC12,ARRDC3,LRWD1,SLC25A17,NFYB,KCNQ5,TPBG,LILRA1,PDE1A,DAPK1,STXBP6,MRPL51,CDK5,GNG3,PATE2,RNF26,MAP1LC3A,RAB13,SNAPC5,RPP21,NDC80,PLAC8,CYB5R3,DSN1,SLC25A23,ZC3H15,SFTPC,PDSS2,SLC6A4,TOB2,YIPF5,FNTB,NME4,PPFIBP1,SYNGR4,HEXB,SLC45A3,NDUFA4,CYTL1,SHMT1,DRG2,CALR,SNAI2,TRUB1,THBS3,ADCY2,TSG101,MAMDC2,PKIG,MOBP,ZNF507,STAT1,PAX6,LMBRD2,MRPS33,EIF2S1,UGP2,LMO3,HEXIM1,PRDX2,DPP4,MSX1,CHRM1,IL3,P2RY11,DLG1,TLR6,KCTD9,CD151,RPN1,SP4,DYNLT3,ZBED4,WASL,CD79B,SDC4,REP15,TMCC1,GOLGA7,RAB14,BVES,APOBEC3D,PC,RAB5A,NDUFV2,ZNF526,NEK2,NDUFB7,KCNA3,F10,SSBP1,PTN,TMEM31,RAB39B,CSNK1G3,MRPS11,AKR1C1,CNTROB,FTSJ1,SREK1IP1,HUWE1,ABHD10,PRND,CPLX2,MEPCE,EIF3G,UBE2L3,CCIN,PMAIP1,TTPAL,PDE4B,CYP3A43,SPEM1,CAV1,B4GALT4,RPS2,YIPF3,TCEAL8,LXN,TMEM205,NDUFC2,TRIM34,ITGB5,RGL2,ICOS,NINJ1,PNMA3,DPH5,RB1,CORO6,TRIM29,TMEM127,GSTA2,HCAR1,MCL1,FAM53C,ALG11,NDUFA1,HFE,GPR35,DDAH1,CREBZF,JAK2,PROK1,TRIM36,MRPS18C,NT5DC1,LY6H,LILRA2,TNKS2,HSPB2,STK3,CBLN1,COMMD9,DCAF12L2,PTP4A3,PLSCR1,PRSS23,GPC1,GPR17,PLCB1,ZNHIT6,ING2,ARL2BP,CHRM3,TSR2,SPP1,FRZB,CDK12,DLK2,PLG,DMTF1,FBXW7,TNFAIP6,PSMB7,KCNJ2,CTU1,EPHA4,PSMD10,GCLC,NPY1R,CPLX3,TNNI3K,CITED1,ARL4D,LIAS,TXNDC17,FAM81A,EHD4,CEND1,ZNF511,STAMBP,HNRNPF,SLC25A1,MAGEB10,CXCR3,HOMER3,TAF1D,ADORA1,SLCO3A1,SPATA2,KCNJ10,SHPRH,PCGF6,GRM1,SLC29A1,SURF2,MAGED2,GJA1,CCNA2,TM4SF20,REEP4,RNF222,AASDHPPT,YWHAZ,STARD3NL,ABHD8,ICAM2,SLC8A1,CAPN2,LSM14A,BOK,TNR,TM4SF18,ASPA,BCL9,ELMO2,LYPD6,TRPC1,HS2ST1,GTPBP8,DR1,CBX3,MIS12,TMEM89,PRNP,CAND1,HSD17B10,GABRA1,ZNF263,TPPP3,SGTA,USP6NL,MTDH,SNX10,CA2,DLST,GTF2F1,GSTCD,TMED9,E4F1,BCL6,SSX2IP,PSMC3,CDH11,JAKMIP2,FAM83B,SNRNP40,PIK3CA,IVNS1ABP,NDUFS2,TMEM185A,SF3B1,TAB1,ADORA3,APEX2,AKR1B1,MAD2L1BP,TMEM47,AP1S2,LY96,ANKMY2,CNN3,RBM27,ZBTB39,CPT1B,RPIA,VTA1,XAF1,PICALM,COX6C,LST1,PIK3AP1,FEM1C,COCH,PSD2,ATP1A3,BAX,PEBP4,GH1,NUDT2,NPM3,TSPAN15,TMEM38B,GSTM4,CRTC2,MT1E,CD81,LRRC40,DPH3,CRISP1,ELK3,POLR2L,POLDIP3,HGS,RHOBTB3,FSTL1,UBE2E2,TAS2R13,DBR1,GNRH1,WDSUB1,ZNF451,PRKCE,TSPAN17,PRKRA,TMEM170A,RNF133,COX6B2,CGGBP1,PHF13,RPL26L1,NF2,PARP2,BANF1,ABHD12,SESTD1,CARTPT,FOXA3,KLHL1,CYGB,NUDT9,IL17F,PPAT,TNF,GGH,CHRAC1,CCR4,KLF3,LZTFL1,SNRPB2,TFB1M,CDC7,MPPED2,PRL,FBXO8,NDST3,SLC19A3,SGMS1,RBBP8,MGAT4A,TRIM45,ATAD1,DUSP21,CYP2C9,IGSF11,MRPS34,CDC20,ZDHHC4,WDR5B,SNRPG,XRCC5,TIMP4,ACCS,TYROBP,FHOD3,SLC35B3,WDR11,NHEJ1,PEX13,AIPL1,TBC1D25,NBN,TNFAIP8L1,VMAC,IL2,SEC13,FEM1B,UBE2G2,MRPL9,MECR,MRPS17,SGIP1,SUPT3H,UPRT,FXN,RAMP3,TMBIM1,CYTH4,IFT172,CPNE2,TOX4,KLRC2,CENPL,IER3,NUCKS1,SULT1B1,RPE,KLHL25,TMEM165,IRF7,MFAP3L,FAM3C,PTP4A2,VEZT,SLU7,LYZ,TOPORS,WSB1,SLC25A5,PRR13,SLC35E4,FAM136A,FAM151B,ZNF518B,ADCK1,CYBRD1,MACROD1,DMPK,MBD3,CDC23,MPG,TANK,SYNGR3,BRAP,KCTD3,PIH1D1,RDH11,NKAP,LBX1,GNGT2,SSPN,CNPY1,LRRC8A,ELFN2,GALC,RP9,HAUS2,DLGAP4,CMA1,GRIK1,SNRPE,RRAGB,GALNT2,RASL12,IL18BP,ANXA4,PELO,GMPS,TTC9C,THUMPD1,GORASP2,RXRG,SNAP25,CCR7,IGF1,PDE7A,DUSP3,SUCLG2,ZNF581,VPS18,GHRL,KIF3C,CIAO1,ATP8A1,RPS20,SLC12A2,RUNX1,GJC1,NAA16,TYMS,MED10,TAPT1,ZFAND6,SCML1,DIRAS2,MREG,ACER3,EIF5B,ARHGAP12,PFKFB2,SRFBP1,ANKRD6,PDE12,FAM161A,YTHDF2,MAGEC2,PSEN1,EDA2R,LCORL,FKBP1B,LMO2,AQP11,TLCD1,RBP2,SSBP4,CLEC6A,KCTD17,RASSF8,MGMT,SP1,ITM2B,MTCH2,MDC1,TRAPPC6A,IMPA2,UBA52,FUNDC1,AP1M1,ECHDC1,TMEM196,TADA3,TRAM1,ETNK2,CCDC106,CLDND1,RPS10,SPRY1,KCND3,FUBP3,ROCK2,KRIT1,VPS72,TRAF6,TBCCD1,RPL18,TKTL1,GIN1,GPR160,POLR1D,PSMD3,DTWD2,CNPY3,SRI,NCAPG2,CYP4V2,APLNR,POLE3,GP9,RNF10,TEX261,ZDHHC16,RAP2A,MSH6,MDFI,PPP1R11,CD209,ST3GAL2,TAS2R7,FBXW4,IP6K1,IL2RB,PTGFR,GK5,SSNA1,GLCE,SPINK9,SLC25A24,SUPT5H,PDCL,TRIP4,RPL10,STAR,OR4A47,DCTPP1,EID2B,PRCP,CPXM1,CD34,FBXL4,THAP1,TAB2,SRPK2,CCDC90B,RGP1,TRAF3IP3,PIWIL1,TMEM107,RPA2,GADD45G,LDB2,YPEL4,CRY1,AIP,CD40,TNFSF15,SLC6A2,PMPCA,TLR8,NOG,MED22,ARFGEF1,CDIPT,TNFSF8,ZNF428,PDE2A,PYCR2,RAB6A,RGN,CTTNBP2,SCAND1,PSMD7,PLAC1,CDK7,SIN3A,BTG3,DPEP3,TMEM183A,GADD45A,IGFBP3,GRPR,CD9,RUSC2,S100A11,ZNF622,ATG9A,SLC25A27,VPS54,TGFB2,RBMS2,MX1,BOLL,PIGA,GLOD4,THOC3,CAP2,TMEM81,EXOC3,SAP18,DDR1,TIA1,SPG21,SLC22A6,RNASEH2C,EIF1AX,HSPD1,TCEA2,LRRC28,PARD6A,NPC2,TMEM115,PNPLA4,NRM,WDR45,THAP8,MPV17L2,CRYBA1,HSPB6,SERTAD2,GNA11,HSPA5,FHL3,FAM20B,TICAM2,GPRASP2,PQBP1,PPWD1,TRIM44,LRP10,NR1I3,ITGB8,BTG2,VAV2,CCDC3,GNB3,CMC1,NUFIP2,HINFP,TMEM229B,RHOU,DLG3,RPL22,CEBPE,TMEM176B,RANBP1,RBM5,CTLA4,ATF3,PRSS37,PDLIM3,MAP1LC3B,DEFB1,IFRD1,ACSS2,SEC61G,CENPM,EMX2,HOXB8,SSH3,GFM1,GAL3ST4,PRM1,ADIPOR1,FZD6,MET,SLC7A11,POPDC3,RETSAT,SNX11,RPLP1,MT1X,UBE2V1,SERPINB9,TIMMDC1,HELT,TRNP1,IMP4,PDE6A,TBCEL,UNC45A,PRSS35,FKBP2,TMEM87A,NUDT1,RALB,ISG20,GMNN,CYP26A1,SNRPA1,CTDSPL2,ARL6IP5,ABHD2,ANKRD46,CEP70,TNFAIP8,DTL,PSMG2,NDFIP1,KDM1A,CCDC22,WNT2,GMDS,NRGN,CSRNP3,TRAPPC3,LDB1,MFSD3,BIRC5,ARL5B,ESYT1,F2,YKT6,VPS26B,ANKH,AANAT,EDC3,SAP30BP,HAPLN2,NAA30,C9orf72,PTGER2,CDR2,NETO1,CGRRF1,DDX39B,HSD17B8,IRF9,LSM4,DOK6,SEMA3C,HERC3,PSMB4,RASSF4,SERPINA3,KCTD20,SKAP2,CLK1,RSL24D1,TRAF1,BRS3,ZMAT3,MGST3,BAD,TSPAN3,HAS3,PRPS1,AKR1E2,CRHR1,NOC4L,UQCRC1,LRRN4CL,SSBP2,PDCD10,GDAP1L1,WTAP,RPL31,ZSWIM7,PHOSPHO2,NMRAL1,MAT2A,TMEM198,TRAPPC2L,RFX5,CDKN1B,CMBL,SCHIP1,MEA1,TAF9,SLC15A1,KCTD16,PLEKHF1,AHSA1,ZBTB6,GPR78,HNRNPAB,TRIM62,TEX19,ZNF655,CD200,TMEM168,TMEM220,ST8SIA4,NCK1,LRP3,STRADB,SIAH1,GLO1,RAB1A,PDCD1LG2,AMELX,VSTM4,NEU1,PELI1,PIGK,CNOT8,MAP1B,FBXO31,VSTM2L,KLF12,MLN,IAH1,WDR12,TCTA,PCP2,SOD2,ADD2,SCN2B,ANKRD10,TEF,SMARCB1,HTR2A,STAP1,ACTR1B,ABCC2,FMO1,STARD5,SUGP1,SDHAF1,ALG5,DCAF16,SRD5A3,CLRN2,DNM2,REG1A,PLCXD3,C1QL2,MMP20,GTF3C4,PSMC5,PRSS1,APEX1,AKT2,GAB1,ITPRIPL2,CHST10,KCNG3,SOX9,COTL1,PNPO,GPM6A,TICAM1,HS3ST3A1,RFC4,LCN1,TLR5,AQP3,PRELID1,ETFA,CD59,ECD,HPCAL1,LIPT2,MRGPRX1,SEMA7A,NAP1L5,APOC2,CYB5B,MED4,ZCRB1,BCKDK,TRMT5,ARHGAP19,TACR1,CEP57L1,CA14,DIS3L,NAP1L3,CEACAM5,EMILIN3,DRD3,MTA3,CHRM5,NACC2,GPR34,TBC1D1,RPF2,XBP1,TIMM13,ERCC3,GABBR1,PDLIM4,THG1L,STARD7,ZNF436,WBP11,EGR1,DIO2,ZNF343,SYPL1,CHTOP,TMEM126A,GPR75,SETD3,FOSL2,GNPAT,ACP2,ACTL6A,PIK3CG,RPSA,NPBWR1,UBE2S,HYAL2,ERLIN2,RHOH,ARHGAP15,RACGAP1,CORO1C,RBM3,CCDC126,RRP7A,STT3A,MAGEA4,FMOD,ADRB3,CA12,SLC7A1,TBC1D16,CMTM7,SPATA4,LEMD3,CSRP1,IRF4,CCND3,ARL6,STX5,RAB11B,HSDL2,LYPLAL1,DYNLL1,ABCF1,DUS4L,PLP2,SMG5,RNF139,THOC6,PYCR1,TNPO2,HINT1,RPAP3,RXFP2,RAB9A,CCL11,MARCKSL1,SDR16C5,IFNAR1,SLA2,ALCAM,JUNB,CCL24,SNRPD1,LIPA,SMAD9,RELL1,TIMM17A,RNF182,PTPN5,UFSP1,MB21D2,LCN15,PGAP3,HM13,MCCD1,SLC39A10,VCPIP1,DDIT3,SLITRK1,SRP72,EDEM2,FIS1,CACNB2,HCFC1R1,RPL28,CYP4F22,MVD,STK38L,ARFGAP1,PIGC,SHC3,CDC26,PREP,SUV39H1,RGL1,RPL4,HBP1,CKS1B,DYNLRB2,RBM41,COPE,SLC25A3,RWDD1,HCFC2,PRKCB,IRF2BPL,LSM5,DCTN3,SKP1,CHCHD2,KRT8,PRELP,CSF2,PCYT1B,GCHFR,GJB1,HNRNPH3,LCP1,AGGF1,ZNF200,IZUMO2,TPST1,TP53TG5,DIRAS3,ATG16L1,HDAC11,SIGLEC5,TTLL10,VWF,ATP6V1D,GPR37,ESD,CDKN2D,TMEM39A,ART5,CDK17,PSMB10,PTPRZ1,IFI16,SART3,FAM174A,SUPT4H1,MYLIP,VPS39,INA,CFTR,ATG3,CLPX,CLP1,TULP3,HS3ST1,BMPR1B,ADH1B,RANBP10,SRM,MED27,MPP1,PSMD1,BARX2,FOXC2,CRYZ,CRYBA4,PITPNA,RAB32,BLVRA,APOBEC3B,MLH3,PCBP4,BGLAP,CDC42SE1,COX7B,RHOG,NOL12,FAM83A,ASB11,SDHC,RGS1,TTR,SEC61A1,RSBN1L,METTL18,GAD2,ASCC1,CDH7,SVIP,SMUG1,UBXN2B,DUSP18,TPD52L1,ZNF770,ZNF345,KIAA1958,EID2,MAEA,LYRM2,FBLN5,FOXD3,CXCL10,CTSA,DPAGT1,PPIL3,PHTF2,ZCCHC7,GPR83,LPCAT3,ZHX1,KCNIP2,SERTAD1,ERRFI1,FA2H,HNMT,THAP6,TUBA1B,CKB,HMGB1,MRPS26,PHF7,GNG11,EIF2B2,ZMYM6,ARF1,BTBD10,PRDX3,PDCD5,EMILIN1,ZBTB26,LRRC14,SPHK2,RCHY1,FGR,MRPL12,ARF6,B3GALT2,PPT1,ZDHHC24,SEC22A,MAP2K3,DCTN4,DOK5,LSM12,FIG4,RPL7A,CXXC1,LEP,SH3BP4,SMARCE1,PITHD1,CETN2,TADA1,ZC4H2,ASPM,EFNA5,ZC3H14,CBFB,CACNG3,RIT2,LRFN3,TNIK,S100B,PDZK1IP1,OR5K1,PDE6D,UBE3A,MAGEB1,SLC6A7,DICER1,DDIT4L,RNASE4,SAP30,SLITRK5,ZNF362,FGF16,POU5F1,HBM,MSN,RPL19,IL21,MID1IP1,TDP1,SPCS1,GLIPR2,PLEKHF2,SERINC1,SNRNP70,PNRC1,SLC41A1,LAMTOR2,MXD1,MFAP1,MED29,TMEM106B,UCP2,UBE2I,FHIT,ARL11,MAP3K3,MRPL16,TECR,RNF7,ARGLU1,EZH1 |
| 1.031e-23 | -52.93 | RNF149 (ring finger protein 149) | protein interactions | 284996 | 535 | 258 | 19454 | 5460 |
ARF1,CYB5R3,RAN,SEC61B,PRDX2,LRRC8A,RBBP4,CHP1,B4GAT1,RAB11A,TMEM183A,SCFD1,PFDN2,CNIH4,ATP2C1,HSDL1,HADHA,GPM6A,PSMC1,STX7,GINM1,TMEM231,PGRMC1,NOTCH2,RAB6A,VAPB,ATP5PO,EMC9,FAM3A,PSMB5,ATP6V1A,SNX1,SNX2,PPIA,ERLIN1,RAB11B,OS9,ATG9A,PRDX1,PDIA3,EMC6,CDK5RAP3,PSMD10,TMEM30A,SLC20A1,JAK1,ERP29,RBBP7,EMC8,SEMA4C,ACVR1B,TMED7,DCAKD,CSNK1E,EMC10,FAF2,PPP2R1A,LGR4,ERLIN2,IFNGR1,RPN1,GDI2,RAB6B,STX12,PLD3,VAMP3,STUB1,ENO1,SCAMP2,GANAB,SLC11A2,TMEM74,TXN,NRSN2,RAB14,SNX3,TECR,SEC63,CSK,HMOX2,SDF2L1,NAPA,RDH10,SYVN1,SPCS2,RAB33B,SLC7A1,USP8,DAD1,TMEM209,RABL3,SEC22B,ADIPOR1,SLC35E1,CNP,CDK1,COX6C,PTP4A2,HSP90B1,STOM,GOLGA5,SLC12A2,PTPN1,HACD3,SRPRA,HSD17B11,PSMB1,ANKRD46,TMEM199,BAK1,ATP1B1,POR,ESYT1,DNAJC7,RAB1A,STX8,EHD4,TMED1,ERG28,HAPSTR1,TSPAN17,RNF133,EMC2,HINT1,ERLEC1,TOM1,ARF4,PRDX4,CCDC47,SELENOK,LBR,UBE2V1,GNG10,CTLA4,AP1S2,ATP5F1B,TAGLN2,NDFIP1,MANSC1,PSMB6,ALG5,ATP6AP2,PSMD1,CCT2,CKB,SPCS3,SERPINH1,ZMPSTE24,BMPR1A,TMEM106B,RAB5A,ARRDC3,EMC1,UFL1,GOSR1,UBE2D3,RNF5,RER1,BOLA2B,BET1,GOSR2,SEC22A,ADSS2,PALS2,FAM8A1,FDFT1,LAPTM4A,PTK7,RAB35,CD63,NRSN1,STX5,RAB1B,OSBP,VAMP7,RAB5C,PPIB,DDRGK1,ZDHHC14,DRG1,RUVBL2,EFNB1,PDIA6,RUVBL1,SLC20A2,VAMP8,RANBP1,TMEM59,NCSTN,EEF2,RAB4A,HGS,CDIPT,SEC61A1,SRP54,STX10,RAB2A,CFL1,DNAJC5,RAP2C,ATP1B3,HFE,TEX264,TXNDC17,LRP10,PGK1,PRDX6,RAB9A,LITAF,CLDND1,BNIP3L,NTPCR,SDCBP,USE1,SSR1,FGFR1,UBE2M,GSTP1,STT3A,EEF1B2,GLT8D1,UBE2G2,COMT,CAMLG,RAP1B,RNF128,SLC39A10,DNAJC1,TMED9,VTI1B,MIF,ILVBL,LMAN1,RAB39B,TMPO,DUOXA2,STX6,PGAM1,DHRS7,GAPDH,RUSF1,ATP2B4,STX18,TGFBR2,TOLLIP,TMEM33,SRPRB,FKBP8,RDH11,RAP1A,TFRC,SURF4,SFTPC,BMPR2,ACVR1,SELENOF,TSPAN3,CERK |
| 1.288e-23 | -52.71 | EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) | protein interactions | 2146 | 1479 | 586 | 19454 | 5460 |
EP300,RTL9,HSPA8,HDAC5,XRCC5,PYM1,SNRPA,MT2A,SAP18,SSR3,RPL27A,KLC2,CTBP1,ATP5F1B,MLF2,CCDC85B,BRMS1,TIMP1,FTSJ3,CHTOP,H1-10,PDIA6,RUVBL2,CCT8,PABPC1,TOP2B,HNRNPDL,RPL28,CDCA7L,HMGN4,VDAC1,ISG15,RANBP1,SUPT5H,MAX,KLHL12,RPL18,ZRANB2,MTA2,CORO1C,EED,MAGED2,SRSF1,GNB3,FABP5,HMG20A,TCP1,TRIR,LYAR,EIF2S1,PPIB,MRPL9,HSPB1,DRG1,YWHAB,SMAD9,FKBP4,PRDX6,EXOSC4,UGDH,HSPA5,KDM1A,SMYD3,PLP2,GTF3C4,PPP1R8,SPTBN1,E2F6,UBE2M,GSTP1,IDH2,SDCBP,PSMC5,EIF2S2,PSMA6,LIG3,RPS3,SUCLG2,PPP1R10,BUB3,RPS17,MORF4L1,SUB1,MAT2A,CALU,ATP1A1,RC3H2,EIF3G,IDH1,RPL3,RAB13,ERO1A,ABCE1,SNIP1,FKBP8,CAPZA1,KPNA2,SRPRB,ZMYM4,WBP11,TAF2,PSMC3,ACOT13,CRABP2,ARPC3,NEFL,EEF1B2,SYNCRIP,SURF6,SHPRH,RPS16,ABHD16B,PGAM1,RPL10A,RPS2,SNRNP70,SMAD4,TUBG1,NUP50,HADHA,UPF3B,POLA2,PSMC1,GPC1,NSFL1C,IL1A,IL1B,RAB6A,PPP1CB,IDH3B,H1-5,MYL6,ATP5PO,RPL37A,AP2M1,EIF3K,CYB5R3,RAN,ARF1,CPSF1,FAU,GNB1,SNRPB2,CHCHD3,RPL35,RBBP4,DYNLL1,MCM4,MCM3,SAMHD1,AK3,NOP16,CFAP20,DPP10,LMNB1,BLVRA,RPS24,FHL3,ARGLU1,CDKN2C,RFC3,RFC2,MCM6,ETFA,TRIM37,RBBP7,LASP1,G3BP1,SAP30,FEN1,RBPJ,OXNAD1,EZH2,HP1BP3,PCBP4,PHB1,MYEF2,LRWD1,ZNF593,CNTROB,CCAR2,RPL7,NOP58,TRA2A,EIF3D,PRDX1,TAF7,PRPF19,PSMD3,NQO1,RPL23,PPP3CA,TRAF6,ARPC2,H2BC12,SLC39A9,SS18,POLDIP2,MBD3,RPL4,NUCKS1,SMC4,GTF2I,NPM3,SNRPN,TPT1,CPSF4,SAP30BP,RPS14,EPHX1,RPLP0,HSP90B1,JUP,CDK1,LMNA,PTEN,RPS20,GANAB,EZH1,TMSB4X,EIF4A3,STUB1,PELP1,RPL22,DYNLT3,RPL13A,SLC25A4,LDHA,RAB14,MAGOHB,GMPS,PPP1CC,TUFM,AR,NONO,ATP5F1A,PYCR2,CTSD,NAPA,LGALS8,HINT1,ZC3H11A,SLC25A10,EHD4,PRDX4,EIF3E,OLA1,ARF4,RPS13,HSPE1,THRAP3,BACH1,CTNNBL1,RPL15,SMAD1,ING1,DDX39A,EEF1A1,MTA3,APEH,GEMIN7,ILF2,DMAP1,SRP14,HACD3,PLGRKT,SLC25A12,G6PD,ZBTB2,POLE3,TOP1,ARF6,ZMYND11,LRRC40,TLE1,CALR,ESYT1,SLC2A1,EPOP,DDX5,SF3B1,TAPBP,RPS28,PEBP1,ARMCX2,EEF1G,PHB2,SRSF2,TRA2B,GPC4,ZC3H14,LAP3,CNDP2,PRMT5,DLST,VDAC2,RPL10,NCKAP1,GADD45G,PSMB6,CBX5,MATR3,TAGLN2,STAT1,BAG3,UFD1,CPSF2,CUTA,ZMAT3,PSMD1,HNRNPAB,HNRNPC,PSMA4,LDHB,MYC,SERPINH1,H1-1,RPS26,H2AZ2,FBXW11,PSMD14,S100A11,CCT2,CKB,CIRBP,MYO1B,TRIM21,EWSR1,RPL31,CBLL1,RAB18,PFDN1,RPS4X,CCAR1,MX2,RUVBL1,HNRNPF,EEF2,RPS7,H1-3,TUBA1A,TRMT1L,SMARCB1,TUBB4B,ANXA4,CCDC71,SIN3A,RAB35,HSP90AB1,CCT7,SUMO2,SNRPD3,RAB1B,HNRNPL,CTNNB1,XPO1,OLR1,YWHAG,RAB5C,RPL6,WWP2,SEC61A2,ZCCHC10,LAMP2,ARMC8,MAGOH,CBL,POU5F1,DDX1,DRG2,DLAT,PGK1,MAPKAPK3,PML,TMEM263,SEPTIN6,LIN7C,RPL27,UGP2,OIP5,HDAC3,RPS15,CDC42,WWP1,SSR1,HBB,MACROH2A1,SEC61A1,CSNK2B,CDIPT,UQCRC2,RPGRIP1L,CTSB,CFL2,CFL1,MTPN,CCNB1,RPL7A,RAB2A,AKT1,SMARCA5,UNC79,OAT,GLOD4,MECP2,DHX9,SOS2,MAP1B,RPL17,PHF1,CSE1L,HNRNPK,H3C1,NUP107,PSMA5,TMSB10,RPSA,PCMTD2,CAPZA2,SURF4,GATAD1,RAC2,CDK6,DSTN,RAP1B,UBE2N,ALYREF,SSBP1,TLR1,MYL12A,BRMS1L,CAND1,API5,ELOC,GAPDH,TPM3,TSPO,MAP4,SMCHD1,H2AC4,RPL24,EMG1,OLFML3,AZGP1,CMAS,CSRP1,PYGB,NOP53,PGRMC1,SLC25A3,ARCN1,ARMCX3,LARP4B,USP39,RPS9,ZMAT2,SNRPD2,SNRPD1,GLIPR2,ENO2,S100A6,MAD2L2,JAK2,ERH,TUBB,REEP4,B4GALT3,ACTB,PRDX2,PYCR1,RAB11A,ACO2,LSM14B,HSP90AA1,RPS5,BRCA1,YWHAZ,SRSF7,PCNA,HNRNPA2B1,HSPD1,SLC25A5,SSRP1,FLOT1,RAD21,PSMD12,GTF3C3,ATP5F1D,ACADS,ZNF592,ARL5B,ZBTB16,ZNF397,PPP2R1A,ACTN4,RPL29,ANP32A,VDR,ZNF263,NAA15,RPS11,EXOSC3,GDI2,RPN1,ATP6V1A,RPLP2,RPL8,RPL9,DHX15,NUP35,SRSF10,PPIA,INA,ZNF207,BCL7C,HNRNPA1,VPS26A,HMGA1,RAB32,PDIA3,COTL1,HNRNPD,RB1CC1,SKIC8,TCEA1,SOD1,HELLS,ARMCX1,FBXW7,YKT6,PDHB,SEC22B,HNRNPH3,RARS1,ALB,MSN,ENO1,EIF2AK2,TUBA1B,GNAI2,DEK,SH3BGRL,UBE2L3,UBB,TMOD3,RPL26,TAF5L,BAHD1,MAPRE1,AP2A1,SMAD2,IGF1R,RPL23A,PQBP1,SFXN1,RAB1A,SMN1,TRIM63,HUWE1,EXOSC8,TAF1D,GBE1,CCT5,FBP1,CMPK1,ACTR2,RB1,LDLR,MYBL2,KRR1,SMAD3,PTPN1,RPL12,CWC15,MDM2,NCBP2,HTRA1,RPL35A,ATP1B1,SUV39H1,ATP5MG,MOV10,BRD3,EIF5A2,NME2,SPP1 |
| 1.985e-23 | -52.27 | Apc2 (Adenomatous polyposis coli 2) | protein interactions | 42871 | 807 | 356 | 19454 | 5460 |
ABCE1,SLC16A1,RPL3,SLC25A11,CAPZA1,H2BC14,KPNA2,MRPL47,TAB2,SYNCRIP,EEF1B2,CDC5L,TMPO,RPS16,KARS1,RPL10A,RPS2,HNRNPH2,EXOSC4,THUMPD1,UGDH,HSPA5,MARS1,ZC3H15,KDM1A,MRPL10,SPTBN1,RPA2,PSMC5,EIF2S2,MOB4,RPS3,PPP1R10,BUB3,KCTD9,RPS17,NAA50,MAT2A,DNAJC10,EIF3G,RTCB,PDIA6,RUVBL2,PABPC1,CCT8,HNRNPDL,POLDIP3,RPL28,KIF2A,RPL18,CRKL,SRSF1,LANCL1,DYNC1I2,LYAR,TCP1,EIF2S1,PPIB,MRPL9,GSTM3,YWHAB,DRG1,HSPA8,XRCC5,RFC4,SNRPA,PYM1,MRPS7,STAU1,HNRNPA0,RPL27A,NCOA5,PSMD6,PSMD4,ATP5F1B,RPL39,DNAJB6,CHTOP,H1-10,HSD17B10,ZC3H11A,SEPTIN7,KATNAL1,DLG1,H2AC25,MSH6,EIF3E,RPS13,OLA1,HSPE1,RPL15,EEF1A1,TBK1,SRP72,CASK,MRPL49,ILF2,SRP14,HACD3,AIFM1,DBT,TRAPPC6B,TOP1,ESYT1,MTDH,PNO1,MBD3,SMC4,RPL4,EIF5B,GTF2I,EEF1E1,PSMC4,RPS14,RPLP0,HSP90B1,JUP,LMNA,CDK1,MRPS34,ACAT1,RPS20,GSK3A,GANAB,RTRAF,EIF4A3,PELP1,RPL22,RPL13A,LDHA,NONO,PPP1CC,TUFM,ATP5F1A,FHL3,RPS24,RFC2,RFC3,SRSF4,PPWD1,G3BP1,RBBP7,NUP153,FEN1,CTSA,HP1BP3,RPLP1,PHB1,THOC2,CACYBP,ATXN10,RPL7,NOP58,EIF3D,WDR11,MRPS35,STOML2,PRPF19,PRDX1,RPL23,PDCD10,HADHA,SKP1,G3BP2,ETF1,PRDX3,MYL6,ATP5PO,RPL37A,RAN,SNRPB2,RPL19,RPL35,RBBP4,DYNLL1,MCM3,MCM4,RFC5,CUL3,LMNB1,DHX9,MAP1B,RPL17,HNRNPK,CSE1L,RPSA,TP53,ATP5PB,ALYREF,RPL32,SSBP1,MIF,TPM3,ELOC,GAPDH,MAP4,KPNA1,RPL24,SMCHD1,DLAT,PML,RPL27,RPS15,CDC42,CD2AP,LUC7L3,SRP54,CSNK2B,EIF4H,CFL1,ARHGAP21,CCNB1,RPL7A,IGF2BP1,TRIM21,EWSR1,ABCF1,RPL31,PRPS1,CCAR1,RPS4X,RUVBL1,HNRNPF,RPS7,EEF2,TUBA1A,H1-3,DCUN1D5,RPS23,PDHA1,TUBB4B,PLS3,CCT7,HSP90AB1,SNRPD3,AASDHPPT,SNRPA1,RPS10,HNRNPL,ISG20L2,EXOC1,NGDN,CTNNB1,YWHAG,YWHAH,TSPAN10,RPL6,ARMC8,CDC23,DDX1,DDX5,SF3B1,RPS28,RCCD1,PHB2,EEF1G,SRSF2,MRPL12,CSNK1A1,EIF4B,PRMT5,INTS10,DLST,RPL10,MATR3,PSMD1,HNRNPC,LDHB,HNRNPAB,RPS26,KIF3C,FBXW11,CIRBP,CCT2,CKB,RPL23A,TCOF1,NKRF,PPP1R12A,PTGES3,SMN1,FN3KRP,FARSA,CCT5,RPL12,MRPS23,CDK9,RPL35A,ATP5MG,SPCS2,GID8,RPA3,PDHB,SF3A1,HNRNPH3,RARS1,RPS12,TUBA1B,ENO1,EIF2AK2,CTNNA1,UBE2L3,RPL26,MAPRE1,YPEL5,SRSF7,MKLN1,MAEA,HNRNPA2B1,SLC25A5,HSPD1,ZYX,RPS27A,GTF3C3,ZNF592,ACTN4,RPL29,OTUD6B,FAF2,HSDL2,SNRPE,RPS11,GDI2,RPN1,RPLP2,RPL9,RPL8,DHX15,HSBP1,PPIA,ZNF207,HNRNPA1,PDIA3,MRPS26,HAX1,HNRNPD,SKIC8,CYFIP2,ARCN1,SLC25A3,USP39,RPS9,SEC61B,SNRPD1,SNRPD2,ERH,ACTB,TAB1,TUBB,PRDX2,RPS29,PYCR1,RPS5,HSP90AA1,PFDN2,YWHAZ |
| 2.109e-23 | -52.21 | ORF7b (ORF7b) | protein interactions | 43740574 | 751 | 336 | 19454 | 5460 |
RETREG2,ORMDL1,H2BC12,MAVS,SPCS2,MTDH,B2M,YKT6,DAD1,TMEM209,SS18,RABL3,ARHGAP1,FUT8,SEC22B,SLC35E1,ST7,ABHD5,LMNA,HSP90B1,GOLGA5,SH3GLB2,TM9SF1,HNRNPH3,MET,TNFSF15,STUB1,VAMP3,EIF4A3,CTNNA1,SCAMP2,GANAB,ALB,NRSN2,TMOD3,SNX3,YES1,VKORC1L1,PDCD5,SEC63,WDR83OS,PCDHB1,FLRT3,TUFM,HMOX2,TMEM106C,ARFGAP3,NAPA,EPHA2,GGCX,NSDHL,LTBR,RAB1A,SFXN1,BSCL2,HSD17B10,HINT1,EMC2,PTGES,TMX3,ELOVL6,HSPE1,B4GALT7,TUSC3,ELOVL7,MDC1,CCDC47,SELENOK,ALG11,DDX39A,TMEM156,SRPRA,HACD3,PTPN1,LDLR,TES,EXTL2,CALR,TMEM199,RELL1,HM13,RAB23,SLC2A1,NME2,MUL1,ESYT1,TMEM256,HADHA,CLDN1,NPTN,STX7,NT5C3A,FAM234A,GINM1,TOR1AIP2,CA12,PGRMC1,NOTCH2,PRDX3,RNF182,VAPB,SLC25A3,SLC23A2,SEC61B,GPR89A,LRRC8A,LGALS3,ACTB,REEP4,ABHD12,SNRPB2,B4GAT1,VEZT,TM9SF4,TMED4,MCM3,FAS,MYO6,LMNB1,SCFD1,HSP90AA1,HNRNPA2B1,SYPL1,PCNA,OPA3,SCD5,GAL3ST1,ACVR1B,SEMA4C,TMED7,TPBG,IFNGR1,LGR4,TMEM45A,RPN1,CTNNA2,STIM1,GDI2,PCDH17,BZW2,STX12,TMEM14B,PLD3,OCIAD2,NEO1,MFSD5,GJA1,SNX17,SPTAN1,TLCD4,NUP35,RAB11B,TMEM248,PDIA3,HNRNPA1,ITPRIPL2,TMEM164,TMEM30A,LRRC57,SLC35D1,SLC20A1,TEX264,LRP10,BANF1,PSEN2,TMEM254,PRDX6,ARFIP1,NAPG,AIF1L,LPAR1,GRPEL1,BNIP3L,MARS1,SPTBN1,PLP2,H2BC11,GALNT1,SSR1,USE1,UBE2M,LEMD3,ATL1,NECTIN2,SRP54,CALML5,SEC61A1,STX10,SGTA,PTPMT1,ACP2,SLC25A1,PTPN11,CCNB1,CFL1,CFL2,RPS17,ARL6IP6,GORASP2,ST13,ATP1A1,OAT,CSGALNACT1,SORD,C1QL1,RUSF1,DDR1,GLCE,SLC16A1,RAB13,CYBRD1,GALNT12,YIF1A,SRPRB,CSE1L,SLC6A8,FKRP,FKBP8,PREB,UBL4A,CD38,RPSA,GPD2,ACVR1,SYNGR3,ITGA6,SYNCRIP,STT3A,CAMLG,COMT,UBE2G2,XXYLT1,EXT1,AKR1B1,DNAJC1,VTI1B,CAND1,TMED9,ARL6IP5,SNAP25,TMPO,SLC38A2,STX6,LMAN1,KARS1,FAM20C,DHRS7,SELENOS,CD81,TPM3,SLITRK5,SLC35A1,TMEM70,NUS1,RPL10A,FITM2,SNRPA,PEBP1,JAGN1,BMPR1A,DDX39B,XRCC5,VSIR,RAB5A,TMEM177,TRA2B,GOSR1,TLCD1,TIMM17A,PHB2,SSR3,RER1,HIGD2A,LDAH,BET1,GOSR2,IL6ST,MRPL12,CAV2,VDAC2,EFHD2,GGT7,RETREG3,LRP12,REEP3,ATP5F1B,TAMM41,NDFIP1,CBX5,ALG5,MYRF,ENTPD4,LDHB,SNRPB,STX16,SLC30A5,SLC38A1,ZMPSTE24,TMEM87A,CYP1B1,EFNB1,RUVBL2,PDIA6,VDAC1,SLC35A2,VAMP8,NETO2,MIEF1,STBD1,PGAP2,H1-3,EEF2,HPCAL1,SEC61G,PTRH2,KDELR1,CLDN12,PSME2,LAPTM4A,SRSF1,ADGRG1,STX5,SPINT2,PEX13,RPS10,EIF2S1,CYP4F8,VAMP7,HSP90AB1,RAB5C,WWP2,XPO1,DDRGK1,DEGS1,FKBP4,DDT |
| 2.927e-23 | -51.89 | cellular response to chemical stimulus | biological process | GO:0070887 | 2411 | 921 | 18204 | 5365 |
SLC2A1,LHB,UBE2L3,EGLN3,YES1,BIRC2,SLC23A2,DUSP1,CH25H,HILPDA,SYK,CCR4,DERL2,CD40,TMBIM6,PRDX6,HDAC6,PRR5L,TESC,S100A8,CREB3,SELENOT,IL2RA,NHERF1,NPPC,MAP2K6,NGB,CHCHD2,SYP,CCL2,PDE2A,WBP2,PIGA,DRD1,CACNB4,MIR16-1,CHRM3,GPR75,HBE1,TLR2,G6PD,RARRES2,CYP1B1,FKBP4,SLC12A2,VPS54,PICK1,VAMP3,P2RY11,XRCC5,TBK1,NPTX1,CDK4,STAT5A,PPIF,IL17F,PIK3CA,CD47,SLC13A5,NDUFS2,ICAM1,NLGN1,P2RY12,PDCD4,STAU1,CAMP,MIR15A,MIR143,PRDX1,LAMTOR3,GPX7,IL18,CSH1,KLF3,ABCG2,BACE1,CD58,PIK3CG,MIR140,PDE4B,FASLG,INSIG2,PDE1B,NSMCE3,ABHD2,IL15,FGF23,MIR455,ALPL,VEGFA,SLC38A2,LAMTOR2,MGST3,NR2E1,PIK3R1,RAN,PIK3R2,VKORC1L1,KLF1,CUL3,IPCEF1,OSM,CCL1,AMIGO1,OPRK1,FZD4,CAPN2,MIR493,RXFP2,ROMO1,IGF1,NFKBIA,UCP2,UBE2W,ABCB1,NSG1,CALR,TNFAIP3,GH1,TXNRD1,GSTP1,AGTRAP,BAK1,TXN,MAP1B,VDR,MT3,CXCL11,OXTR,MIR182,CEBPE,PPP3CA,FAM107A,AKT1,AIFM1,KCND2,IL1B,ESD,IFNA13,RTF2,TLR6,ITGA2,PIP5K1A,PHC1,NR1H2,CCL28,PCSK9,MIR187,NRP1,CDK5RAP3,PRKCE,EGLN2,KRT8,MIR448,XBP1,RPL13A,EIF4A2,TOLLIP,TERC,MIR320A,SLCO1B3,SLCO2B1,FAS,PID1,KIT,CCND1,IL2,MIRLET7B,PAK2,AR,SOD1,SLC2A8,MIR223,UBE2K,FCER1G,BAX,EIF4E,TRAF3IP2,TP53INP1,AHCYL1,CHRM4,IL6,GNAQ,IFNA10,PTP4A3,MMP9,ACAA2,CD86,ADIPOR2,PADI2,GNAO1,MIEF1,PPP1R12A,VPS26B,AKT2,CD274,CA2,MPV17,MX1,ERRFI1,PRNP,HAX1,OXSR1,CXCL14,DAPK3,SMYD3,RIGI,PAX6,CRYZ,EDNRA,WNT10B,SRXN1,OPTN,HP,CDC42EP4,CD80,CIB2,TNFRSF1B,IFNK,PLCB1,TLR9,ATG7,MGST2,HM13,SELENON,CDC73,MIR96,IFNA2,FABP4,ACTB,CYP11B2,TNF,VAPB,SHMT1,CX3CL1,MUL1,XCL1,AVPR1B,ATP1A1,RDH12,PDE12,PDIA3,EDA2R,PHB1,ERLEC1,TOP2B,STUB1,DNAJC10,CYP4F12,CYP3A5,HFE,RAB11B,CXCL12,CDK5,MIR98,TBC1D24,FBP1,IL1RAP,FOLR1,TMSB4X,LRAT,CDK9,CCL18,ILK,PTGER1,CASP4,RAB31,CYP11B1,SLC22A12,GREM2,SLC25A5,LRRC8D,NUP35,RB1,CXCR3,GJA1,MIR214,CKLF,MIR17,NLRP3,CCL25,CASTOR2,FOXC2,TIFA,AIF1,PDCD1LG2,CSNK2B,UBIAD1,BRINP1,MDM2,GNAI3,TP53,HPCA,SOST,DDX5,LEPR,SOD2,NEK7,POR,ACKR3,MSMP,UGT1A1,PCGF2,TMEM38B,TRIP4,LILRA3,GHR,PTPN1,BRINP2,LARGE1,HSPA8,PPIB,CLCA1,KLF4,CYB5B,CER1,DLG4,TLR4,CBR3,LGALS3,CYP2C18,B2M,MLC1,KLHL22,HELLS,NQO1,CDKN1B,GSTA1,SUV39H1,CHMP5,RHOG,IRAK4,SLC16A1,CXCL13,AOX1,ALB,DPEP1,ZFAND2A,MIR370,MAP2K3,KLHL15,ADD1,GJB2,SESN3,AANAT,RAB29,GABRG2,KCNMB1,IL18BP,JAGN1,CXCR6,COL3A1,SDF2L1,DHX9,SPP1,GLRX2,SEMA5A,CCR6,MAT2A,CCR7,STAT6,SULT1A3,CST11,HAND2,CXCL1,SRSF7,OSER1,ADRB2,ELMO2,RASGRP2,SLC38A9,OR51E2,IL5,EIF4EBP2,CPNE2,GAD2,OS9,KDM1A,CTSB,NR1I2,SYNGR1,IRF8,CCS,GNA14,MRC1,HDAC5,CCR1,IL1R2,CPEB1,GHRL,CCR5,ERO1A,BAG3,CBL,STAT2,SOX9,BECN1,LRRC8C,HBB,CYP1A1,BRINP3,RAB13,RORB,KCNC1,CCL5,KCNB1,DEFB124,IL2RB,AKAP12,EPHA4,TLR3,MIR200A,PELP1,FBXO32,CCL17,PTGER2,TIMP3,IGF1R,SFRP1,PPIA,CDC42,SOCS2,YWHAH,CCL3,ATP5F1A,IL12A,SCG2,BCL10,REN,CNTFR,LILRB1,SOD3,IL6ST,CSF2,STX8,IRF3,OPRM1,EEF1E1,CLIC2,MAVS,CCL27,CMA1,GPR35,GSTA2,RUVBL2,STAMBPL1,GSTA4,EFNA5,HTRA2,SOCS5,IL20RB,HSPA5,MYD88,IL4,AQP3,FXN,EPHX1,MIR149,CCDC186,TXNRD2,MIR146A,PLP2,STC1,SLC7A11,KCNJ10,SMAD3,CRHBP,COL1A2,WNT2,HNRNPD,CCN3,EIF4A3,RAP1A,PLSCR4,CLTRN,TFRC,TMIGD1,GNB1,RALB,RPL3,CCL23,AKR1B1,NFKBIL1,ATF3,NKX3-1,FCGR2B,ADIPOR1,STAP1,GSTT1,CHI3L1,HCLS1,FOS,CYP2C9,PML,RPAP2,B3GNT2,EIF2S1,IL15RA,MT1M,TERT,WBP1L,NFKB1,MRAS,CCL4L1,GNA11,ALOX5AP,GSTM4,LAMTOR1,TRAF6,TICAM2,HP1BP3,NDP,PACRG,MT2A,SFTPD,CCL19,UMPS,ADGRE2,NINJ1,GPR37,SNX10,IFNG,HBA1,MEF2A,PRKRA,MGARP,KCNJ11,PTGES3,CMBL,FAM162A,SST,SRC,SH3BP4,CALY,DAG1,GNG2,SMARCA5,PHB2,TFPI,SLC25A23,ATF4,TRIM21,EPS8,LEP,AKR1C2,MT1A,AKR1C1,TICAM1,NFE2L2,MECP2,TMEM199,LILRA1,BNIP3L,SLC41A1,IRF1,PQBP1,GSTO1,IFI16,PGK1,GSTK1,NTRK2,SHOC2,ACTR2,EP300,PDCD10,PIK3R3,SLC1A1,CYP2R1,CTNNB1,SLC1A2,HYAL2,CTSK,MIR95,NPR2,GPT,CCL24,GPX1,LMNA,P2RY4,UBE2G2,NOP53,TBC1D4,PYCR2,NDNF,DDI1,SMAD4,TANK,GRB10,SELENOS,DRD3,MT1E,BCL2L1,STXBP1,JAK2,STAT1,LRP6,TIRAP,HBM,RAMP3,AKR1A1,GSK3A,MIR545,ADCY2,BAD,UGCG,DERL1,DEFB114,ACACA,TUBA1A,CDC42EP2,CREBZF,GRIA1,CD14,EIF2AK2,GNAI2,PLAA,STK26,TRIM24,SLC8A1,CRKL,TXNRD3,CYP2C8,MSN,NCOA5,CXCL9,FOXP1,YWHAG,MIR185,UBE3A,IL12B,RNF14,CSK,BGLAP,MIR107,PRL,JUNB,JUN,HSPD1,LDLR,LANCL1,MT1X,NEUROD2,SULT1B1,GPX2,FLOT1,IFNGR1,RXRG,PPARA,SLC1A3,GPR37L1,VEGFC,ELK1,IFI27,ADCY3,SIN3A,AQP2,SERPINB9,VAV2,RRAGB,PMAIP1,MIR210,CD36,LDOC1,KCNH1,SLCO1A2,PCK2,ABCC2,ILDR1,RGS10,RWDD1,GNRHR2,MYBL2,SYNCRIP,GUK1,JAK1,RGCC,LILRA2,CPNE1,AQP4,MSX2,GPX5,MIR21,CXCL3,CCR3,ZC3H15,ADIPOQ,RAF1,PTGFR,H2AZ1,IL10,ROCK2,TRAF1,HRH3,PAQR8,TRAF2,CX3CR1,MIR145,PPP1R1B,RPS3,LY96,TRIM6,HMGB1,GABRB3,MME,GPX6,EPHA2,RDH11,CXCR1,PTK7,CXCR4,CAB39,PYCARD,HRAS,AGER,RHOB,VAMP2,TNFRSF14,CXCL10,HSP90B1,GLRA2,SPHK2,ASIC2,GUCY1B1,GPX3,TRA2B,ADO,CGAS,OGG1,CFTR,RPS16,RAD23B,INA,CACYBP,SLC29A1,CCR2,HSPB8,HSD17B1,ABCC5,RRAGA,CXCL8,LPAR1,TAF7,CLIC4,ITGA6,CYGB,CLEC7A,GPR173,AZI2,MIR34A,IL13,TSHR,P2RY1,COMT,PRDX2,CCL11,PTPN11,CCL8,DDIT3,NR4A2,SRP54,SLC6A4,EPO,TPBG,IKBKB,IL34,GAPDH,EGR1,CHCHD4,MKKS,ESR2,PYCR1,NFYB,MIRLET7G,NCSTN,IL7,EZH2,CHRNB2,IL3,CHRNA7,GAB1,TSPO,UFD1,RAP2A,STK24,GSTO2,SESN2,JUP,SELENOW,PRKCQ,PGR,SP1,JAML,CYP7A1,PPARG,PTGER4,CSNK1A1,CCNA2,RPL23,CRIP1,PLSCR3,TGFB2,IL1A,NAT2,TWNK,PCNA,ATP5F1B,TF,NUDT2,IL2RG,GCLC,NFKBIB,PTPN22,GSTM2,FMO1,ATP6V1G1,PEX13,FOLR2,DDIT4,TNFSF18,MTDH,ADTRP,CCL20,SMAD1,CHRM1,ATP2B4,CRYGD,IRF7,ACTN4,CAV2,SLC25A24,SHC1,MAP1LC3A,CHGA,PRKCB,SUMO1,RAP1B,OAS1,CRHR1,RNF126,GPX4,TADA3,CCL21,MIR20A,CTNNA1,MTF1,AIP,MTARC2,LITAF,ATP1A2,MIR106B,FMO2,GSTM3,GLRA1,SOS2,HNRNPA1,LY6H,MYC,SELENOF,MIR126,CREB1,TUBA1B,TXNDC17,IFNAR1,GPR17,DAPK1,ZFAND6,PTGES,PRDX3,CYP26A1,SRM,HTR2A,INPP5K,KLF9,RPS6KA4,CDK1,CHRM5,SMAD5,NFIL3,CYP2F1,GLYAT,CDK5R1,ACHE,CAV1,IFNB1,PRDX4,ATP6V1A,MCOLN1,SOCS3,GPBAR1,HTR1A,RBFOX2,USP8,FKBP1B,ZYX,HSP90AB1,MEF2C,CAV3,MSTN,IFIH1,RBM22,GABRB2,GFI1,CYP2D6,MIR421,MIR342,SMAD2,MIR31,SERPINB6,BRCA1,ATP1A3,CLDN1,IDE,MIR324,HBEGF,PTN,CD4,LILRB4,ARL6IP5,GPR22,EGR2,PSEN1 |
| 4.129e-23 | -51.54 | ATXN3 (ataxin 3) | protein interactions | 4287 | 436 | 219 | 19454 | 5460 |
RHOG,TRAF6,HAX1,BCL2L1,RPL23,PRDX1,PSMD3,PRPF19,MARCHF5,BCL7C,KCTD10,PPIA,DNM2,PHB1,PSMB4,PSMB5,MAP1LC3A,RPN1,NME1,RNF126,HSDL2,FAF2,ACTN4,PSMD12,HSPD1,SLC25A5,HNRNPA2B1,NDUFA4,BAG2,ARHGAP19,HSP90AA1,USP13,RHEB,PRDX2,RBBP4,TUBB,MAD2L1,CNOT6,UBE2S,RAN,SNRPD2,RPS9,ATP5PO,PSRC1,SLC25A3,ARCN1,ANXA7,RRAGA,TOR1AIP2,IDH3B,PRDX3,DET1,CDKN1A,MCMBP,SRI,PXMP2,PSMC1,BIRC2,PSMD7,DNAJC7,HDAC6,DBT,AIFM1,HACD3,HSD17B11,PSMB1,RAD23B,CCT5,YTHDF2,DDX39A,RPL15,HUWE1,HSPE1,TRIM63,RPS13,MDC1,PRDX4,SLC25A10,SNAP23,SEMG2,PC,ATP5F1A,NONO,TXN,TECR,UBE2L3,UBB,STUB1,ENO1,GANAB,RTRAF,RPS20,RPS12,TIMM23,HSP90B1,RPLP0,RARS1,PSMC4,RPS14,GTF2I,GABARAP,RPA3,SYVN1,SQSTM1,HSPB1,LAMP2,WWP2,XPO1,HNRNPL,TCP1,ASIC1,SNRPD3,HSP90AB1,LANCL1,CCT7,S100A8,TUBB4B,KDELR1,RANBP1,TRAF2,SOX2,TUBA1A,EEF2,PSMA1,RUVBL1,RPS4X,TFG,POLDIP3,PRPS1,CCT8,PICK1,EWSR1,PDIA6,CKB,CCT2,PSMD14,SERPINH1,CREBBP,PSMA4,LDHB,PSMD1,BAG3,PSMD4,ATP5F1B,PSMD6,PSMB6,NCKAP1,APEX1,DLST,NFKBIA,SDC2,UBAC2,NUFIP2,UBE2D3,EEF1G,PHB2,XRCC5,SF3B1,HSPA8,EP300,RAP2A,BECN1,RPS2,KARS1,DNAJB2,GAPDH,RPS16,MIF,SSBP1,EEF1B2,SDHB,MGME1,GNPAT,TMEM31,CAPN2,PSMC3,UBL4A,ATP5PB,TP53,RPSA,CDK4,ACTR1A,NEDD8,PSMA5,CSE1L,KPNA2,HNRNPK,SLC25A11,SLC16A1,ATP1A1,PSMB2,SLC25A1,NDUFAF2,CFL1,TRIM54,SMURF1,SF3B6,CREB1,RPS3,LIG3,PSMA6,SEC61A1,CSNK2B,PSMC5,RPA2,ACACA,CYC1,KLF4,UBE2W,CAPN1,SUMO1,HDAC3,GRPEL1,MARS1,HSPA5,MAIP1,PML,LSM12,PGK1 |
| 4.294e-23 | -51.50 | cytosol | cellular component | GO:0005829 | 5475 | 1873 | 19108 | 5553 |
IGF2BP1,TOP2B,S100PBP,NANP,TXNRD3,NUP42,CDC42EP4,KIF2A,SLC25A17,RGS5,AKT2,HGS,AKAP12,TRAPPC6A,NFE2L1,MALSU1,RNF34,ANAPC16,NOB1,EIF2B2,DPH6,FGD2,VCPKMT,PNO1,ETF1,S100B,GABARAPL2,MMP14,PSMA5,PTPN22,PPP3CA,KCTD10,SNRNP40,PRKCQ,RPL10A,UMPS,STK4,HSP90B1,LSM6,AFAP1L2,DELE1,IFIT2,CRMP1,FAU,BLOC1S3,EIF4B,FCHO2,GNPDA2,NCDN,RAB18,BAALC,SKA3,VTI1B,ARMC8,EIF3J,PRKAB1,BCL2A1,FANCG,CYB5R3,NUDT5,COA1,USP13,ECD,OTULIN,PLAAT5,FBXO30,RAP1A,URM1,NAE1,ARFIP1,AIFM1,NUP107,HSPB2,POLR3F,PIP4K2C,HEXIM2,CSNK1E,PABPC1L,NT5C3A,DISC1,PSMA3,NOSIP,SH3GLB1,IL2RG,CITED1,SAP18,OAZ1,RGS1,H2BC12,ACOX1,IVNS1ABP,CACNB3,PTPN1,FKBP8,EEF2KMT,CPLX2,SNX5,RPS16,GLRX,MAP4,MAP3K12,BAG2,EHD3,PLS3,TRAF2,NSFL1C,MARS1,ACTR1B,ADRA1A,MPG,CPLX1,DOK6,ODC1,NMRAL1,NDUFA12,TTC8,EIF3K,RAB9B,DDX5,NUF2,DDAH1,NMI,NMRK1,NEK9,DCTN4,SRXN1,TSPO,CFAP298,UBA52,VPS54,CFL1,RPIA,DOK5,PSMB3,DYNLL1,ARFGAP3,GUK1,AP5M1,RASGRP2,BIRC5,AHCYL1,JUP,DIS3L,KLHDC8B,POLR2C,TKTL1,DSN1,SMG8,STK3,RPS3,DCTPP1,GIMAP4,IRF4,SNIP1,RPL7A,GRAP2,SCFD1,CTTN,VRK1,RAP2C,POU1F1,TDRP,ASPA,MECP2,RNF144B,CLU,SPR,WRAP53,NUDT3,DNTT,IGBP1,EXOSC1,MSRB1,DCTN6,ATG7,POLA2,GJA1,AR,ZYX,CCS,SPATS2L,IL12B,KLHL12,CCL3,PPAT,UGDH,IL18,GNPAT,MAP3K11,ATP8A1,IDH2,CPNE1,ATG16L1,DICER1,PARP11,TOMM40,DUSP3,GID8,HEXA,POLR3GL,IFTAP,TPM3,RBBP4,RAB3A,PAK5,AGAP2,SMYD3,CDK5,TMEM147,HSPB6,CDKN2C,PLSCR1,MAGOH,RPL7L1,EHHADH,METAP1,STK38L,CDK5RAP3,RAB1B,UFD1,TIA1,PLAAT3,TOB2,GTF2E2,WEE2,CASTOR2,YAF2,SIAH1,WBP11,TMEM266,UBE2E3,TRAPPC2L,ACOT6,TTC1,PPP1R3C,SERPINB9,CTNNBIP1,TRIM68,NDE1,ASB8,CAMK2N2,SQSTM1,ZBTB14,PDE2A,YWHAZ,GTPBP1,RAP2B,EEF1AKMT3,GRAP,IL15,DCK,PPP2R5A,MRPS16,PAK6,PDE6D,TFCP2,GSK3A,STX6,CRABP2,MAGED2,CDKN1A,RRAGA,FKRP,IL1B,PDCL,CAMK1,CDC42EP2,RPL24,NBN,BCL2L1,AGO1,CSTA,INPP5K,ANKRA2,TOLLIP,RPS23,RPL10,TNNT2,FKBPL,ACO1,SNAP29,LANCL2,RPL18,PPP2CB,BPNT2,HSD17B1,TYMS,CHMP1A,SOX2,DROSHA,DCUN1D3,LZTFL1,ATAD1,DLG1,NT5C2,NIBAN2,GLUL,ARF4,ADD2,RBP2,PRKCA,OSTM1,GSTM2,SIGMAR1,ZCCHC17,WDR11,ASB1,SNAP25,RPL31,FKBP1B,ZCRB1,ABHD5,DLG4,SPRY1,DAG1,COPS2,PLEKHA8,ATP6V1E2,PREPL,PARD6A,ACTR1A,STK24,NDN,TNIK,XAF1,ATP6V1A,GPRASP3,ZNF397,AKT1,PPFIA3,PDAP1,GFPT1,ATG101,UBE2V1,PELO,KCNIP3,G6PD,CCHCR1,CRYM,RPL12,ERLIN2,CMPK1,ITGAV,PSMC5,STMN2,CDC73,TERT,SLC2A1,COPE,PDE4B,BOLA2B,HNRNPF,ANAPC4,UCKL1,MRPL50,BTF3,ANAPC2,METTL21A,ZNF322,FABP7,RNF10,CDC42EP3,LMNA,AP2A1,MMACHC,TNFAIP8L3,DMTF1,COPS7B,MKKS,RARS1,PDE8A,TOM1L1,NTMT1,DFFA,PHETA2,SDS,STRADB,CLIP3,EEF1G,RRAGB,NFKBIA,EDC3,CEP70,CASK,TRIM5,RPS24,RPAP2,SLC35F6,ACOT13,PSMB7,CAPN1,ETNK2,ORC6,SMAD5,VPS28,COQ8B,MOV10,PPID,RPL27A,AK5,WDR77,CMA1,ALYREF,TRIM45,EXOSC4,RPS12,HYCC1,PNPO,ARL4A,CREBBP,FBXL3,MIS12,TRIM37,TMIGD1,YES1,PRM1,CENPL,USP46,ARFGEF1,BRAP,SNRPD3,GPX1,VIRMA,CRADD,DAPK3,CARS1,ENO1,PFKFB2,RAB35,PRKCB,CRKL,FIS1,NTRK2,RHOBTB3,STAT6,PPFIBP1,DYNC1I1,ACOT8,ENDOD1,SORD,SULT1A3,SEPHS2,RND3,TRAPPC3L,LYPLA1,DHRS4,XPO1,DES,LIMS2,PHACTR1,PSMD12,CTNNA2,NKAP,KRTAP12-4,TCAP,PRR13,PSMD7,MAD2L1,TICAM1,ARGLU1,SEC23A,ATP6V1G1,CYTH4,SPMIP9,DTYMK,JAK2,FGFR1OP2,ABHD14B,GPHN,PPP5C,STX17,CRYZ,LDHA,EXOSC8,LCMT1,TFG,SRC,NDC80,ASMT,CFAP418,SEC13,STAT2,PFDN4,UBA3,HDAC3,CA2,RAB27A,TBC1D10C,GPAA1,RPS10,GMNN,DUSP9,TRAK2,RNF208,COMMD9,SNRPD1,MAGOHB,CARD19,TRMT10B,ARCN1,ACO2,EXOC3,GHR,ATAT1,FKBP4,CCT5,NOS1AP,PC,PRKAG1,LYPLA2,WDR83OS,SHMT1,PRMT2,MAP3K14,CCT7,PRRC2A,RND2,TRAPPC3,PICALM,PPP1CB,AKR1C2,SNX14,PRDX6,MYLIP,GEMIN7,CHCHD1,EXOC2,EEF1E1,G2E3,CDKN1B,ATXN10,NDUFAB1,MEF2B,TMOD1,TXNDC17,RALGAPA2,HINT1,METAP2,FAM162A,ORC5,PAIP1,CBLL1,ECHDC1,SMG5,SYNCRIP,GSTM3,PTHLH,LSM3,ELP6,PSME1,SNRNP48,VAMP2,STAMBP,NAIF1,SOCS5,VDR,RPL19,NAA16,GSTO2,GSTA1,COPS4,IKBKB,TRMT112,AKAP1,USP8,SFRP1,BTG2,ISYNA1,JOSD1,KPNA2,NUP35,TRIM21,PHF7,STAMBPL1,MZT2B,SCLT1,ADH1B,HDAC6,SHC3,PYGM,TP53INP1,DNAJC3,MX1,PHKA1,KRTAP8-1,PACSIN3,ACVR1B,DVL2,DPH3,TPH2,ACTR2,COX19,IP6K1,LRRC14,GBE1,EXOC5,SP4,HSBP1,SNX17,NKX3-1,BUB3,CHAC2,LYPLAL1,OGG1,DMAP1,HIKESHI,CSK,THTPA,STX10,HNRNPA1,PRDX2,UBE2G2,VAV2,SNRPG,EIF5B,CHKB,STX5,AKAP17A,HSPD1,DYRK2,RPS13,RB1CC1,PHAX,LGALS3,RGL1,DUSP6,TMCC1,HOMER3,HYCC2,RB1,TRIM11,GABARAP,C2CD4C,CDK7,SLC25A20,FBXL7,CHCHD6,RAB6B,OPRK1,STUB1,PARM1,FBXW4,SRI,SNX2,RPS27L,SLC7A14,TRAPPC6B,TCIM,SERPINB6,HSD17B11,PRPS1,APOBEC3G,SRSF2,DDX1,MID1IP1,SYS1,EIF4E3,LARP4B,GSTA2,COPS5,YWHAG,NCKIPSD,PSRC1,INPPL1,RAD21,TRIM32,RAB29,LORICRIN,NAT2,GPX2,SSU72,CETN2,PDCD10,RPL10L,GAD2,ARFGAP1,COMMD8,CRAT,ABHD10,IRF8,OTUD7B,PDE1B,SEC14L1,RPL26,HOMER1,RBCK1,TNKS,COX4I1,DESI1,CRYAB,HMGCS1,FEM1A,NCALD,APEH,CENPP,CTNND1,RPL8,GNAI2,PLCB1,FABP5,JAK1,TAGLN2,RBIS,IRF2,HERC4,RHOG,SNRPB,OAZ3,TSR3,SNX3,PPIB,HUWE1,POU5F1,VPS4B,MX2,SMAD4,TMEM88,NME2,UCHL3,PRKACB,CPLX3,CIPC,RNF146,CHN2,RAF1,GSTK1,KIF3C,UNC45A,GCLC,RAB2A,STK11,ZBED3,CDC16,EIF1AX,NUBP2,PTGES3,TUBB4B,NCK1,HPGDS,NOP58,BBS5,TNFAIP1,MAPKAPK3,TIAM1,TRIM26,VEZT,CDC42,MAP1S,MAPKAPK5,TXN,MIEN1,TRAPPC10,TXNRD2,PGPEP1,PSMA6,CSNK2A1,DENND6B,RAB23,PPP1R1B,KCNAB1,RNASEL,UAP1,EED,DNAJB2,PSMB10,UBE2A,YWHAB,AHSA1,TRAPPC4,SH3GLB2,B9D1,DCTD,HMBS,UFL1,RPL7,FAM110B,SRP54,SLC17A5,RGS2,DGCR8,RNF41,KLHL25,COIL,OAS1,HBB,PAX6,PEA15,SNX33,GMDS,POLR2L,WWP1,IRF6,BICD2,UBE2F,TSN,OXSR1,DECR2,AZIN2,FTH1,LPXN,SPIN3,AASDHPPT,OAZ2,RANGRF,BACH1,PRKCE,PCBP4,RIOX2,CAPZA1,TADA1,MLLT11,SDHAF2,NLRP1,SCP2D1,CEP41,UBP1,POMP,C9orf72,SMN1,ST13,AP1M1,PSMD3,CDKN3,SMAD3,METTL18,S100A8,TAB1,RIT2,CYB5R1,NLRP6,CTU1,MMAA,PGM2L1,RSPH1,SPATA2,RTRAF,PIK3R1,PPIA,KLHL22,WWP2,CAMSAP2,CSNK1A1,ITK,PSMA1,NRP1,SPRED1,APOO,UBE2M,NOP53,CMBL,TSPAN15,CALR,RMND5B,CUL3,ATF4,CSE1L,GRB10,CFTR,BABAM1,MKLN1,CD1B,CYB5A,GLTP,FAS,GALE,NR1H2,RPLP0,OPTN,FAF1,RWDD1,RPL26L1,NF2,CAPZA2,SH3BGRL,SRM,SPG21,NLRP2,CLIC2,HNRNPC,ARL2BP,FTSJ1,MTHFS,MAPK4,PELI1,MDH1,HSPA8,FEM1B,NFKB1,TNNI1,PSMB9,SPHK2,CSNK2B,MYL6,NPM3,RANBP1,RIMKLB,PELI3,EIF2S2,FGFR1,CDK4,RPLP2,POLDIP3,PLEKHJ1,DDX42,SKA1,PSMB5,GOLPH3L,CAVIN2,COPZ2,DUSP22,H2BC14,PRKRA,ROCK2,MAP2K6,HNRNPH2,B9D2,ALKBH3,GAMT,NUP37,FABP4,SLC13A5,RPL6,B4GALT3,RPS28,PREP,RDM1,ASB7,PPP2R5E,TSG101,KRT7,FBXO32,KLF12,HCFC2,TUBG1,FABP12,SARM1,MEF2A,HNRNPDL,SGIP1,FBXO44,AAMP,UBE2S,GTF2IRD1,NAA11,DNAJC7,RMI2,COTL1,GOSR2,EEF2,IFI16,TP53INP2,MYL12A,IL1A,TANK,GTF2A1,FEM1C,HNMT,BET1L,CSNK1A1L,PSMG2,ZNF436,MT3,DCTN3,PPP4C,PDLIM3,RPL28,ZBTB33,RAB14,CASC3,CAPN2,CNOT8,MSN,CNDP2,ADD1,CPEB1,HARBI1,ZNRF1,CD2BP2,SLU7,FTL,EEF1B2,CARHSP1,ADH1A,FBXW7,UBXN6,DDIT3,SERTAD2,GCHFR,CAMK2G,TEX264,STARD5,DNAJC2,GPC1,GAS2,PRKD3,SNCB,GFUS,UBE2D1,SLAIN2,RBMS2,SULT1B1,DOHH,PSMC1,PPARG,CHPF,FAHD1,ABCF1,GGPS1,RABIF,TUBA1A,ICA1,ADO,TESC,XPNPEP1,PCBD1,IL2RB,SMAP2,SMURF1,DLST,TSC22D3,PPIL4,SPTBN1,HPCA,UBL4A,RPL35A,ZFAND6,PSMD14,WDR44,AP1S2,BLOC1S2,AIP,BLVRA,MYRF,PRDX4,RGP1,CNN3,SHC1,TES,FBXL4,RPS7,CCDC134,KPNA6,HSP90AB1,CEP97,GARRE1,TREML1,TLE1,CAND1,MTMR6,ARL14EP,KLHL9,ATP6V1G2,IFIH1,GSTT1,AIF1,SRSF10,TTLL10,RHOU,SDCBP,XRCC5,PGK1,FN3KRP,TRAF1,KRTAP4-1,PACRG,PSMB2,DNAJC5,HSPA5,H2BC9,EIF2D,RTCB,JPT1,RGCC,ALKBH5,RBP5,CPTP,CCNF,HSCB,AREL1,GSTA4,TFE3,PI3,UQCC3,POLR1B,RPAP3,WASL,FPGT,MSRB3,AKR1E2,FGR,MDM2,KBTBD13,NUDT7,RPGRIP1L,NFKBIB,MTPN,HSPB1,GCFC2,ARHGAP19,MLC1,RPL23,UCK1,USP38,CBX7,CDC20,YKT6,RPL29,GSTO1,VAMP1,NABP1,DPH5,SRP72,IMPA2,CCNA2,RPE,CRYL1,PMAIP1,PFDN2,SIX5,ETV6,RGS10,STAT1,KIF3B,MAT2B,SMC4,RACGAP1,ALDH1L1,DCUN1D1,CCDC47,CISH,LSM14A,TRIM34,G3BP2,UPF3B,RAB13,UBE2K,COMMD5,SKP1,NMBR,PLA2G4B,CGAS,KPNA1,ACP5,PSMA4,STXBP1,PTTG1,OSBP,HPS6,MORC2,DAAM1,RPL13A,LCP2,PDE12,CDK6,PIR,P4HA2,GOSR1,HTRA1,GDI2,MYD88,PLCB2,ADPRM,PHYH,TAX1BP3,TFEB,ACTB,ARHGEF6,RPL22,BAK1,IRF9,GAB1,ARF6,DNM2,DNAJC8,GTF2E1,TXNIP,EIF4A2,ARL6IP5,TAF1D,RAB31,TAB2,PPP1R12A,PTEN,CLPX,MYH2,LSM5,PGR,ERRFI1,RPS27A,SMAD1,PHF1,MTMR2,PYM1,ARHGAP21,CCT8,TGFB1I1,MIOS,TPPP2,ANAPC11,PTPN11,NECAP1,UBB,USP15,PSMB6,TRAPPC13,PPP3R2,SPSB1,RIGI,OVGP1,RNF167,GNB4,TSNAX,DOK4,SIKE1,DNAJB4,SH2D1A,CDO1,HDAC5,KBTBD6,LRRC1,CTNNA1,VTA1,EIF2B5,GCC1,RERG,ZNF622,GUCY1B1,RPL4,UBXN2B,RAD23B,ZMYM2,GPT,MAP2K1,SHOC2,AFTPH,HNRNPD,TIRAP,RPS2,RPS11,CTNNBL1,TBC1D17,ASB11,TRAPPC1,HSP90AA1,IDH1,GON7,PTPN4,SOCS2,BOLA1,MSX2,MYO6,PGM1,RPL32,FKBP1A,YTHDF2,HSPA14,CDC26,RANBP10,RAB1A,CH25H,VAC14,ZDHHC8,MXD1,DUOXA2,FLCN,PROX1,SEPTIN7,RNF128,PHKG1,H2BC11,RUVBL2,SIAH2,CCR2,EIF5A2,ZBTB16,RLIM,SENP8,ISG15,SPTAN1,CHMP1B,B2M,NKIRAS1,ELOC,EPHB6,AMACR,EI24,STX16,NTAQ1,BEX3,MAP2K3,SNRPE,BAP1,EHBP1,CEP85,FBXO22,FXN,USP5,ELK4,SWAP70,ATP6V1D,SPRED2,PTRH2,HSPB8,TIFA,CNOT7,TESK1,NAPA,ZC3H15,PHKB,TXNL4A,BAX,MYL12B,BCCIP,BANF1,TMT1B,FARSA,CNOT6,INPP5E,SYK,RCHY1,FXR2,AP2S1,PDE7A,RAN,HCLS1,KLF9,CREB3,POLR2D,PIK3R3,FNTB,CCND1,CBL,TPPP,HSPA13,CCDC22,XPOT,PMM2,TNFAIP3,FBXL14,ACTA2,FAM13B,UGP2,PRDX1,CYTH1,ZNF175,COX10,STARD4,GNPDA1,DNAJB6,KRAS,POR,RIMKLA,TBC1D5,OCRL,SPRR1B,COP1,PDIA6,TRIB1,GSTT2B,RTKN,RBM38,PTP4A2,DBT,RNF7,STAP1,PSMC4,CNOT2,RPS6KA4,DYNC1I2,CSTB,UBE2N,STX1A,SERPINB10,HTRA2,FBXO31,RAB9A,TMEM87A,CHMP2A,CHST2,EP300,SUMO1,POMT2,MAF1,AGK,HBE1,ACACA,PDCD5,GNPNAT1,GNB1,ADK,ARF1,PDSS2,MT1A,NQO1,THG1L,PEG10,RBM18,PEX26,AKR1A1,PSKH1,NXT2,PEX13,PADI2,GYS1,RPS17,RPS5,AP1AR,ALDH1A3,CHMP2B,HRAS,CDAN1,PPM1B,EXTL2,NUP153,TAX1BP1,HAUS2,MAT2A,HILPDA,MAP1B,GLRX5,FBP2,PSMC3,SMAD2,RUSC2,UBE2L3,CCT2,VPS26B,SLC66A2,MPHOSPH6,HYAL2,NLRP3,RAB5A,STK38,NGB,EIF3D,GNB3,TRIM27,MTM1,RPL37A,FAH,NAA15,CACNB4,PPP1CC,MIF,DLX1,LIPA,RGL2,SOCS3,NAA35,NRGN,ARMC1,NEK2,RCCD1,RPSA,HECW1,APOBEC3H,EGLN3,NUDT18,PSMB1,NAA30,ATP6V1C1,VPS26A,AIPL1,INMT,MYBL2,LSM4,BAG3,SGTA,TBC1D13,RIOK2,SRSF8,CHMP4C,HBA1,KLK5,PSME2,IER3,FGF1,FBXO9,LGALS8,CRLF3,RPL27,AZIN1,G3BP1,ILF2,TAPT1,EIF3G,IDE,ARHGAP5,GAPDH,ADRM1,SEC61G,TGFBR2,EIF1AD,ZCCHC7,HBM,DTL,EIF2B3,DXO,PXMP2,EIF2AK2,RPN1,TRAF6,CCNB1,PAFAH1B2,SRP14,SKAP2,PICK1,FBXO3,NUFIP2,PPP2R2C,MEF2C,GGCT,UCK2,NDUFAF4,PLSCR3,PYCARD,GAS8,BOLA3,RPS26,ARHGAP15,FHIT,SMUG1,EDF1,TRIM22,CUL2,RILPL2,CIDEB,RAB6A,ACSS2,NXT1,LDHB,RPL39,CDC23,TMT1A,STK26,NEURL2,DRG1,TNRC6C,PRDX3,IPO8,POLR3B,PSMA2,UBE3A,RAB11B,SCPEP1,ACBD6,FGF13,RPS4X,ILDR1,PSMD1,PSMD4,RAB32,S100A6,TRIM36,NEFL,OLA1,CDKN2D,SOS2,COMT,EEF1A1,PIK3CA,GABARAPL1,C2CD2,NFE2L2,TUBB,RNF115,FBXW11,ELMO1,RAB11A,RUVBL1,NEDD8,PABPC1,CAB39,NLRP9,PRNP,EXOSC3,BCL10,LST1,FRMD8,TCP1,CYTH2,ABCE1,SPRN,GSTP1,FOS,EIF4E2,AANAT,USP6NL,ZNF687,STARD13,SMAD9,RAP1B,FERMT2,NCKAP1,FLRT3,MAP3K3,IRAK4,PML,EIF4H,USP14,TNKS2,KARS1,UNC119B,AKR1C1,PSMB4,PEBP1,GCA,H2BC17,CBR3,CRBN,SFN,PNP,TRIM62,MAPRE1,BIRC2,PAFAH1B1,RPL3,ARPC2,IRF3,MAPK10,ARPC3,PDCD4,BECN1,NUDT4,MAP1LC3B,PFDN5,PABPC5,CYFIP2,MXI1,MAGEC2,MSH6,NME1,TNFSF13,UBE2H,KRT8,GMPS,PNPLA4,CKB,RPS9,FAAP100,CACYBP,ASB3,RHEB,GLO1,RNF8,RCE1,IDO1,DLG3,FOXP3,SOD1,STK16,INPP4A,IRF1,PPIG,CD28,RPL35,TESPA1,PIK3CG,RNF14,SUFU,RING1,PITPNA,RPS14,TCOF1,SAV1,SPMIP6,MCMBP,MED27,NUDT19,ADSS2,UBE2D3,GNMT,SNRPD2,TBK1,FBXO11,WBP2,ODAM,VAMP8,CYGB,RABGGTB,IFI35,RPS29,RNF126,KRTAP3-1,MTAP,CDK1,RFXANK,PSMD6,TBC1D16,FZR1,TRIM24,GSTM5,SESN2,STAT5A,RAP2A,NAA50,RPLP1,EXOC1,DCP2,USP30,EIF3E,SMG9,CCND3,TRIM52,AKR7A2,PAOX,CXXC5,PIK3AP1,PSMD10,ATG3,WSB1,EIF4A3,AKR1B1,MVD,STAC3,CHMP5,RIMOC1,AP5S1,SAR1B,CDCA7L,XPO5,POLR3H,DRG2,ANAPC15,PIK3R2,RPL17,TXNL1,PPT1,SAT1,SEC61B,CASP12,ATPAF2,MPIG6B,FBP1,PPM1D,CDCA3,EXOC8,KLHL3,VAMP3,ENO2,DMPK,KLC2,SPSB3,CLIC4,MMADHC,ELP3,MTMR12,SNX1,OSGEP,DHX9,SURF4,IREB2,UBAP1,PIP5K1A,TRUB1,CD3G,MAP1LC3A,PTS,CD151,BPGM,STARD3NL,PYDC2,PDE1A,UBE2I,ROCK1,PEX5L,NUDT1,EIF2S1,PPIH,PAK2,TPT1,BPIFB4,RBBP7,JPT2,RHOB,EIF4E,BAD,BARX2,LURAP1,RPS15,CDK5R1,KLF4,PRMT5,CLP1,SKA2,DHPS,LEP,APBB3,DDIT4,PSMB11,TBC1D4,TP53I3,NR1I3,GLE1,FBXL19,CCDC106,TRIM6,SSNA1,ARMCX3,GPRASP2,PPP2R1A,TMSB4X,SKIC8,SETD4,CNOT6L,RNF187,DUSP10,TXNRD1,MPV17,CTNNB1,NCBP2,PAPSS2,CXXC1,MCL1,IRF7,RINT1,SNAPIN,CDC37L1,RPL9,ILK,SRPK2,TRIP4,FBXO7,DENND2D,PDE9A,PCCB,GSTM4,LSM2,POLR2F,PPFIA2,AP2M1,ESD,VPS4A,LIMD2,TNNC2,SPC24,SNAPC2,GPX4,ELMO2,MT2A,ARHGAP1,RPL23A,AOX1,SLA2,KLHL7,RAC2,TP53,TOM1,RGS6,FAM83B,COPS7A,HMGA1,PAFAH1B3,PMP2,TRIM8,ASRGL1,STAU1,ARMC6,OSBPL8,LCP1,ISCU,RPS20,PTPN5,DNPH1,RPL15,GEMIN8,WDR6,RRM1,YWHAH,CASP4,WDR45,CENPM,PGAM1 |
| 8.282e-23 | -50.85 | PRPF8 (pre-mRNA processing factor 8) | protein interactions | 10594 | 742 | 331 | 19454 | 5460 |
BTF3,BAG3,SNRPB,MYC,SFN,HNRNPAB,HNRNPC,LDHB,ICAM1,RPS26,SERPINH1,CCT2,CKB,PSMD14,SF3B4,SMU1,CMTR1,PSMB6,PPP5C,RPL10,MATR3,ATP5F1B,FBXO22,SNRNP40,RPL27A,MTF1,PIH1D1,UBAC2,HSPA8,SF3B1,HDAC5,EP300,DDX5,DDX39B,SLU7,SNRPA,XRCC5,UFL1,EMC1,SRSF2,EEF1G,STAU1,SERPINB6,PHB2,PPIB,DDRGK1,NT5C2,GSTM3,WWP2,RPL6,HSPB1,MAGOH,FKBP4,AGR2,EED,PSME2,RBM5,PRCC,SRSF1,LANCL1,HSP90AB1,CCT7,EIF2S1,RPS10,TCP1,SUMO2,SNRPA1,SNRPD3,SOX2,NUDCD3,ISG15,EEF2,RPS7,DHX38,SUPT5H,PPIL3,CRKL,RPS23,CSTPP1,RPL18,PLS3,TUBB4B,DNAJB4,RPAP3,OAS1,RUVBL2,PDIA6,RTCB,FBXO3,RPL31,CCT8,PABPC1,ABCF1,RPS4X,HNRNPF,KRAS,RUVBL1,H2BC9,RPS17,CFL1,PSMB2,SLC25A1,RPL7A,ATP1A1,UBE2H,RC3H2,EIF2S2,SF3B6,RPS3,GCFC2,SRPK2,KCTD9,BUB3,HEXIM1,TFIP11,LUC7L3,RPA2,HNRNPH2,CWF19L1,RNF113A,PRDX6,BAP1,DDX46,RPL27,MARS1,HSPA5,RBM22,CSNK2A1,TPM3,ELOC,GAPDH,KARS1,RPS2,RPL10A,MAP4,SNRNP70,RPL24,SYNCRIP,RPL32,ALYREF,TMPO,RBM42,CDC5L,RPS16,FZR1,MIF,WBP11,TP53,RPSA,NUPR1,IK,RPL3,RAB27A,DHX9,SNIP1,MAP1B,SLC25A11,PDRG1,MEPCE,RPL17,CAPZA1,CDC40,TMEM33,CSE1L,KPNA2,HNRNPK,PRPF31,RNF40,CUL3,PFDN2,HSP90AA1,RPS5,RIT1,LMNB1,YWHAZ,RPL37A,SNRPD2,SNRPD1,RPS9,EIF3K,RSRC1,RPL19,SNRPB2,PRDX2,TUBB,DYNLL1,LGALS3,PRDX3,CDKN1A,SLC25A3,RTF2,USP39,TXNL1,EMG1,HADHA,G3BP2,SKP1,FTL,DUSP26,INSYN1,HNRNPA1,PRDX1,PDIA3,PRPF19,PIK3R1,HNRNPD,RPL23,DDX23,RPLP1,KRT8,COPS2,RPLP2,RPL8,RPL9,PHB1,PPIA,DHX15,RPL7,BUD31,ACTN4,LGR4,RAF1,SF3B5,RPS11,SART3,SNRPE,EZH2,CHMP4C,NME1,BAG2,RPS24,HSPD1,SLC25A5,HNRNPA2B1,PPWD1,GTF3C3,RPS27A,COPS4,SSRP1,G3BP1,GNL1,ATP5F1A,FBXO7,RPL26,USP14,PPP1CC,NONO,AR,ASCC1,PIP4K2C,RPS20,UBE2I,PTEN,RPS12,CCNF,OPTN,STUB1,ENO1,EIF4A3,TUBA1B,VIRMA,RPL22,NDN,MGST3,LDHA,TXN,RPL13A,WDR83,SF3A1,TXNL4A,RPS14,SNRPN,RARS1,RPLP0,KRT7,LMNA,JUP,GRM2,LSM2,METTL14,PPIH,RPA3,PPM1G,NCDN,PRPF4,SIRT7,CSTB,LSM8,POLDIP2,BRIX1,GTF2I,EIF5B,HMGB1,RPL4,FBXW7,SMC4,HDAC6,ZMYND11,H2AC14,DNAJC7,KIAA1143,ECD,PSMB1,RPL12,AIFM1,SRP14,HACD3,RCHY1,ZBTB2,TOP1,EEF1A1,CD2BP2,RPL15,CCT5,ILF2,SEPTIN7,RPL23A,HSD17B10,SLC25A10,PQBP1,RNF20,RPS13,PRDX4,PTGES3,SNRPG,RIGI,EIF3E,TSSC4,HUWE1,LSM4,DNAAF10 |
| 8.369e-23 | -50.83 | mRNA base-pairing translational repressor activity | molecular function | GO:1903231 | 293 | 168 | 18094 | 5411 |
MIR198,MIR155,MIR33B,MIR126,MIR100,MIR378A,MIR330,MIR215,MIR383,MIR345,MIR187,MIR338,MIR424,MIR373,MIR26B,MIR939,MIR573,MIR105-1,MIR218-1,MIR150,MIR30A,MIR29A,MIR425,MIR125A,MIR210,MIR223,MIR339,MIR505,MIR10A,MIR877,MIR193A,MIR188,MIR34A,MIR24-1,MIR551A,MIR1260B,MIR148B,MIR214,MIR96,MIR769,MIR30D,MIR20A,MIR28,MIR1277,MIR448,MIR130A,MIR34B,MIR497,MIR145,MIR181C,MIR185,MIR194-1,MIR98,MIR30E,MIR1298,MIR181D,MIR298,MIR548C,MIR204,MIR876,MIR144,MIR30B,MIR301B,MIR195,MIR885,MIR136,MIR374A,MIR346,MIR454,MIR99A,MIR31,MIR17,MIR140,MIR657,MIR625,MIR133B,MIR190B,MIR1-1,MIR92B,MIR186,MIR23A,MIR34C,MIR874,MIR132,MIR25,MIR302B,MIR490,MIR106B,MIR221,MIR503,MIR208A,MIR379,MIR191,MIR15A,MIR153-1,MIR101-1,MIR638,MIR206,MIR148A,MIR9-1,MIR212,MIR384,MIR10B,MIR192,MIR183,MIR423,MIR147A,MIR139,MIR640,MIR491,MIR661,MIR361,MIR129-1,MIR572,MIR208B,MIR152,MIR552,MIR639,MIR511,MIRLET7G,MIR222,MIR340,MIR335,MIR211,MIR708,MIRLET7C,MIR32,MIR99B,MIR16-1,MIR3173,MIR488,MIR492,MIR519D,MIR142,MIR182,MIR146A,MIR920,MIR342,MIR200A,MIR495,MIR143,MIRLET7B,MIR301A,MIR449A,MIRLET7I,MIR106A,MIR137,MIR135B,MIR107,MIR200C,MIR141,MIR130B,MIR29C,MIR590,MIR363,MIR193B,MIR675,MIR205,MIR1271,MIR873,MIR429,MIR21,MIR320A,MIR1224,MIR493,MIR149,MIR296,MIR455 |
| 1.100e-22 | -50.56 | CIT (citron rho-interacting serine/threonine kinase) | protein interactions | 11113 | 1424 | 564 | 19454 | 5460 |
HNRNPA1,HMGA1,MPHOSPH6,VPS4A,HNRNPD,WDR12,SKIC8,RPLP2,RPL9,RPL8,HSBP1,NUF2,DHX15,PPIA,SRSF10,INA,RPL29,ACTN4,PPP2R1A,FAF2,RAF1,SNRPE,RPS11,EXOSC3,RPN1,SRSF7,BAG2,HNRNPA2B1,HSPD1,ZYX,RAD21,FLOT1,SSRP1,RPS27A,S100A10,DHX16,RPS29,PRPF31,PYCR1,ILK,RPS5,CCDC25,HSP90AA1,RHOB,BRCA1,RPS9,SNRPD1,SNRPD2,VPS72,ERH,PRRC2A,RPF1,EIF4A2,ACTL6A,SLC25A3,MFAP1,LARP4B,H2AC1,USP39,EMG1,NOP53,SUV39H1,ATP1B1,PID1,SETD5,GRSF1,BRD3,POR,TRPC1,RPL12,CWC15,CDK9,IL18,CGAS,THOC1,RPL35A,CCT5,CMPK1,H2AJ,ACTR2,NDUFS3,NLRP9,RPL23A,SFXN1,NKRF,TCOF1,PPP1R12A,RAB1A,H2AC6,NOC4L,FN3KRP,VRK1,RACGAP1,RPL26,ZNF687,CDC73,AP2A1,RPS12,ODR4,SPIN3,ALB,CTNNA1,EIF2AK2,MRPL53,DEK,VIRMA,FERMT2,SLC25A31,UBE2L3,COPE,UQCRC1,SEC22B,SF3A1,RARS1,HNRNPH3,RPL26L1,PICALM,PPIH,BRIX1,LSM8,PDHB,NF2,CTNNB1,QPCTL,XPO1,SEC61A2,RPL6,DDX50,BAZ1B,IFI16,DDX1,CRTAP,PABPC1L,RBM5,PSME2,SIN3A,HSP90AB1,SNRPD3,RAB1B,RPS10,HNRNPL,RPS7,NUP37,EEF2,ELF1,TUBA1A,H1-3,DHX38,TRMT1L,LIMD2,HGS,RPS23,H2BC1,PDHA1,PTRH2,PLS3,PIK3CG,MYO1B,ABCF1,FBXO3,RPL31,BCL7B,RPS4X,RUVBL1,HNRNPF,SLC1A3,CPSF2,SNRPB,RALGAPA2,BTF3,HNRNPC,HNRNPAB,RCL1,SERPINH1,RPS26,CCT2,SMU1,DLG4,VDAC2,ESR2,RPL10,CBX5,POLR2B,PCMTD1,MATR3,ZC3H14,TOMM22,AKR1A1,NUFIP2,PPT1,ACAA2,DDX5,DR1,SF3B1,SPECC1L,RPS28,DDX39B,PHB2,EEF1G,FXR2,TRA2B,SRSF2,GAPDH,TPM3,ELOC,ROGDI,PPIL4,AKAP8L,H2AC4,RPL24,SMCHD1,ALYREF,RPL32,ACSL4,SSBP1,LMAN1,RPS27L,RPSA,TP53,IMP3,STRBP,NUPR1,CAPZA2,DISC1,RP9,SURF4,CBX3,DDX42,DHX9,CLPB,RPL17,MEPCE,HNRNPK,CSE1L,NUP107,CFL1,CFL2,RPL7A,SMARCA5,SLC25A1,ABCG2,IGF2BP1,MACROH2A1,SRP54,UQCRC2,PSPC1,DYRK1A,CCDC42,DAPK3,SLC4A10,ELFN1,CYC1,LUC7L3,RAG1,TFB1M,TFIP11,DDX4,DDX46,RPL27,MAIP1,RBM23,BNIP3L,RPS15,WDR3,TRA2A,DPY30,CLPX,PRPF19,PRDX1,RPL23,RSBN1L,KDM2A,DDX23,RPLP1,HP1BP3,XPO5,PHB1,THOC2,LRWD1,ERLIN1,SNX2,KCTD10,RPL7,SPTAN1,CCAR2,NOP58,FAM200A,GFPT1,NUP153,MAK16,TPBG,EZH2,SRSF8,RPS24,SLC39A7,ARGLU1,PPAN,TRIP4,RFC2,RFC3,PPWD1,ETFA,G3BP1,RBBP7,MCM3,MCM4,TOMM40,RFC5,RNF40,NOP16,CFAP20,CUL3,RIT1,MYO6,LMNB1,AP2M1,RAN,PELO,CPSF1,SNRPB2,RPL19,RBBP4,RPL35,RPL7L1,DYNLL1,PRDX3,PPP1CB,MTX2,PRKAB1,H1-5,MYL6,ADNP,CCDC86,HADHA,NUP50,UPF3B,THOC3,G3BP2,COIL,ATAD1,CALR,MPHOSPH10,SLC2A1,PWP2,SRP14,H2AZ1,SRPRA,AIFM1,NOP9,SLC25A12,ATP5PD,PRNP,TOP1,PPP1R18,RPL15,OSGIN2,MTA3,SRP72,MSRB3,ILF2,PPME1,RING1,H2AC25,EIF3E,MSH6,PRDX4,MDC1,RPS13,CTNND1,THRAP3,LSM4,CTNNBL1,NONO,TUFM,PPP1CC,ATP5F1A,XPOT,NCKIPSD,ACAT1,RPS20,RTRAF,GANAB,EIF4A3,PELP1,CYP4F12,RPL22,HOMER1,TECR,RPL13A,TXN,ELP3,MYL12B,EEF1E1,RPS14,MACROH2A2,ZNF574,OXSR1,NOL7,RPLP0,LSM2,H2AC7,HSP90B1,GRM2,JUP,MRPS34,CDK1,LMNA,H2BC12,SQSTM1,MTDH,PNO1,PRPF4,POLDIP2,AATF,NHP2,SMC4,RPL4,EIF5B,SGF29,GTF2I,UTP6,PPIB,RIOX2,TAX1BP3,DRG1,HSPB1,MAGED2,EED,CORO1C,SRSF1,MPDU1,LANCL1,PNPLA8,TMEM97,LYAR,TCP1,EIF2S1,AFTPH,KIF2A,TNPO2,SOX2,PPIL3,SUPT5H,RANBP1,TOP3B,RPL18,CRKL,TAPT1,RND3,MTA2,SMNDC1,SEC11A,ACTR1B,RTCB,PDIA6,RUVBL2,RPAP3,PABPC1,RBM3,TOP2B,CCT8,POLDIP3,HNRNPDL,RPL28,CYP11B1,VDAC1,NUP42,H1-6,NSA2,POLR1B,H1-10,RBM27,FTSJ3,SF3B4,DES,SNRNP40,FBXO22,GPNMB,ATP5F1B,RALYL,CNPY3,RPL27A,NCOA5,RAB5A,HSPA8,XRCC5,SNRPA,RFC4,GNB4,SAP18,HNRNPA0,CSNK2A1,RBM17,ACOT8,RPL10A,TMOD2,RPS2,SNRNP70,DELE1,MCL1,EEF1B2,SDHB,SYNCRIP,CD274,CDC5L,TMPO,RBM42,DKC1,RPS16,H2AX,MTCH2,MRPL47,RRM1,SRFBP1,PSMC3,ARPC3,NEFL,ACVR1,IK,CHAMP1,TFRC,SLC16A1,RPL3,RAB13,SLC25A11,PALM2AKAP2,DUSP19,CAPZA1,SRSF12,TMEM33,KPNA2,CDC40,UTS2,RPS17,MAT2A,RPF2,CALU,RRP7A,ATP1A1,DNAJC10,EIF2S2,PSMC5,LIG3,RPS3,CSTF3,RPL10L,BUB3,GTF3C4,SNRNP27,SPTBN1,UTP15,E2F6,ZNF326,H2BC11,RPRD1B,CSNK1A1L,PRDX6,HNRNPH2,EXOSC4,BANF1,ARHGEF6,HSPA5,MARS1,KDM1A |
| 1.478e-22 | -50.27 | CAPZB (capping actin protein of muscle Z-line subunit beta) | protein interactions | 832 | 1019 | 427 | 19454 | 5460 |
CSNK1A1L,RPA2,UBE2M,HEXIM1,ING5,SPTBN1,CFTR,NDUFAB1,HSPA5,MARS1,ZC3H15,EIF4E,ARHGEF6,RNF113A,EXOSC4,HNRNPH2,DNAJC10,RC3H2,EIF3G,SPOP,ELAVL2,AKT3,RPS17,H2BC9,BCCIP,ZBTB33,CREB1,RPS3,EIF2S2,ARPC3,TFRC,TAF2,IPO8,ANGPT1,ACTR1A,SRPRB,KPNA2,CDC40,CAPZA1,FKBP8,NOSIP,ABCE1,RPL3,BECN1,RPL10A,TMOD2,RPS2,KARS1,CSNK2A1,RPS16,CDC5L,TMPO,COX4I1,SYNCRIP,EEF1B2,PIH1D1,PAFAH1B1,RPL27A,ELK4,STAU1,SSR3,HNRNPA0,RPP14,HIRA,RFC4,STK26,COX17,HSPA8,H1-10,COMMD9,DNAJB6,RPL39,PSMD6,ATP5F1B,RAB4A,RPL18,CRKL,RND3,KIF2A,SOX2,KRAS,HNRNPDL,RPL28,TOP2B,PABPC1,CCT8,UQCC2,ACTR1B,PDIA6,RTCB,RUVBL2,RPAP3,AGR2,YWHAB,ANKRD50,DRG1,CNOT8,PPFIBP1,LYAR,DYNC1I2,TCP1,MEAF6,FAM98A,EIF2S1,LANCL1,SRSF1,CORO1C,ZHX1,LSM2,GRM2,JUP,CDK1,TMOD1,ZNF574,RPLP0,EEF1E1,RPS14,CPSF4,EIF3J,RPL4,GTF2I,ARPC2,SQSTM1,MTDH,CCDC22,CASC3,NAPA,CAP2,NONO,AR,PPP1CC,USP14,ATP5F1A,RPL13A,MAGOHB,TXN,RPL22,EIF4A3,RPS20,RTRAF,ILF2,UBR7,RPL15,EEF1A1,HSPE1,CTNNBL1,CAMK2G,EIF3E,MDC1,RPS13,RNF20,CNOT6L,HSD17B10,NFKB1,HDAC6,MAPRE2,PRNP,MYL6,NDUFA5,TBC1D17,TIMM13,PPP1CB,MCMBP,PTN,SKP1,WASF3,G3BP2,UNC45A,PSMC1,STAP1,RTKN,THOC3,DCTN3,HADHA,NMRAL1,MYO6,RIT1,SP1,CUL2,CUL3,MCM4,TOMM40,RNF40,RIOK2,DYNLL1,RBBP4,TSN,RPL35,BTG3,RPL19,MAD2L1,CHCHD3,EIF3K,FAU,CDC7,RPL37A,EZH2,GPBP1L1,FEN1,TRIM37,G3BP1,HS2ST1,AP1M1,FHL3,RPS24,PSMD10,RPL23,BCL2L1,LYZ,STOML2,EIF3D,ATG7,FIG4,SPTAN1,RPL7,CACYBP,PHB1,DNM2,COPS2,RPLP1,PAAF1,CDC42,CD2AP,OIP5,RPS15,AIF1L,LIN7C,RPL27,BAP1,DLAT,LSM12,BICD2,UBE2H,IGF2BP1,PDCD4,RPL7A,SLC25A1,AKT1,MTPN,CFL1,CFL2,RPGRIP1L,DAPK3,DAPK1,DYRK1A,IDE,SRP54,SEC61A1,CSNK2B,CAPZA2,DISC1,PCMTD2,NUPR1,TP53,RPSA,HNRNPK,PSMA5,RPL17,MEPCE,PSME1,DHX9,CLPB,RPL24,TSNAX,AKAP8L,PLEKHO1,GAPDH,TPM3,ELOC,RPS27L,ALYREF,RPL32,SSBP1,PPT1,NUFIP2,EIF4B,BOLA2B,UFL1,SPECC1L,RPS28,DDX39B,DDX5,CCT2,RPS26,HNRNPC,PSMA4,MYC,BAG3,BTF3,ACAP2,RPL10,ESR2,PSMB6,DLST,PDHA1,PLS3,TUBB4B,DCUN1D5,RPS23,HEXA,RPS7,EEF2,KGD4,RUVBL1,HNRNPF,TFG,PRPS1,DCTPP1,RPS4X,RPL31,EWSR1,MYO1B,MAGOH,DDX1,CBL,WWP2,RPL6,CNOT2,DDRGK1,ACTR3B,YWHAG,YWHAH,SNRPD3,OSBP,COMMD6,RPS10,RAB1B,HSP90AB1,FUBP3,RBM5,PICALM,DCTN4,RPL26L1,RARS1,NFYB,PDHB,MRPL20,PIAS1,DCTN6,RPA3,ARFGAP3,MAPRE1,CDC73,RACGAP1,COPE,TMOD3,NDN,VIRMA,SH3BGRL,CTTN,CCNF,RPS12,MSN,ACTR2,CCT5,FBP1,FN3KRP,TTC4,FARSA,CNOT7,HUWE1,PPP1R12A,RPL23A,NME2,OSBPL8,CNN3,MRPS23,CDK9,RPL12,PTPN1,TIMM8B,TES,PSMB1,DECR2,MYBL2,LARP4B,VAPB,ACTL6A,CYFIP2,YWHAZ,DCAF4,BRCA1,VMP1,LSM14B,RPS5,PFDN2,HSP90AA1,RAB11A,ACO2,RPS29,ACTB,TAB1,TUBB,EIF4A2,ERH,PRRC2A,CNOT6,TRMT6,RPS9,SNRPD1,SNRPD2,RPN1,RPS11,B3GNT2,HSDL2,RPL29,ACTN4,PPP2R1A,ASF1A,DHX16,RPS27A,HNRNPA2B1,SLC25A5,HSPD1,BAG2,MRPS26,HNRNPD,VPS26A,HNRNPA1,HSBP1,DHX15,EGLN3,PPIA,RPL9,RPL8,RPLP2,PLEKHO2 |
| 1.525e-22 | -50.24 | CAND1 (cullin associated and neddylation dissociated 1) | protein interactions | 55832 | 849 | 368 | 19454 | 5460 |
HSP90B1,MRPS34,RPLP0,RPS14,RPL4,EIF5B,AATF,NHP2,PNO1,PRPF4,CASC3,NONO,AR,DEPDC1B,ATP5F1A,RPL13A,TXN,LDHA,RILPL2,RPL22,TECR,EIF4A3,STUB1,OPTN,RPS20,PTEN,PRKRA,RTRAF,HSPA13,SRP72,APEH,MRPL49,PPP4C,ILF2,MRPL11,YTHDF2,COMTD1,RPL15,EEF1A1,MAP1LC3B,THRAP3,SNRPG,RPS13,RNF20,FBXO25,HSD17B10,HAPSTR1,SLC2A1,CD36,TOP1,ARL10,HACD3,SRP14,AIFM1,SEC23A,RNF7,TIMM13,SKP1,G3BP2,COIL,UPF3B,HADHA,TRUB1,CUL2,NOP16,CUL3,RFC5,RNF40,RPL35,RPL7L1,RPL19,FAU,ARF1,RPL37A,FBXL3,EZH2,GTPBP1,DCUN1D3,G3BP1,TRIM26,RFC2,SRSF4,PPAN,RPS24,ZC3H7A,UBE2D1,RPL23,MRPS35,PRPF19,PRDX1,EIF3D,RPL7,NOP58,PHB1,RPLP1,HP1BP3,ZNF326,RPA2,UBE2M,CFTR,GABRA1,H2AC13,MRPL41,HSPA5,RNF113A,HNRNPH2,DNAJC10,ELAVL2,TIA1,RPS17,RPL10L,MRPS21,SRPK2,ZNF330,RPS3,EIF2S2,MRPS28,TNRC6C,MTCH2,KPNA2,TCEA2,MRPS18B,RPL3,SNRNP70,USP15,RPL10A,RPS2,FAM20C,CMSS1,KARS1,TMA16,COPS5,RPS16,CDC5L,TMPO,RBM42,DKC1,SDHB,SYNCRIP,EEF1B2,CD274,PREP,UBAC2,CTBP1,PIH1D1,RPL27A,STAU1,HNRNPA0,MRPS7,SNRPA,YAF2,EP300,HDAC5,HSPA8,H1-10,FTSJ3,POLR1B,ATP5F1B,APLNR,SF3B4,RPL18,KLHL12,ISG15,TRAF2,SOX2,KRAS,FGD2,HNRNPDL,RPL28,RBM3,PABPC1,RTCB,PDIA6,AGR2,DRG1,GSTM3,MRPL9,LYAR,FAM98A,PAIP1,EIF2S1,SRSF1,EED,RPL26L1,HNRNPH3,SF3A1,FBXW7,PDHB,COL3A1,BRIX1,RPA3,PPM1G,CDC73,BRAP,FBXO7,RPL26,CEP97,DEK,VIRMA,EIF2AK2,ENO1,CTNNA1,CCNF,MSN,TMEM108,TNFAIP8L1,TCOF1,NKRF,RAB1A,IGF1R,RPL23A,H2AC14,GRSF1,MOV10,DCUN1D1,RPL35A,MRPS23,NCBP2,ACTA2,KRR1,RPL12,USP39,VAPB,SLC25A3,ACTL6A,NOP53,PYGB,BRCA1,RPS5,HSP90AA1,SMARCE1,ACTB,TUBB,PRDX2,PRRC2A,ENO2,TRMT6,RPS9,SNRPD1,SNRPD2,SNRPE,SART3,RPS11,FAF2,SSRP1,HNRNPA2B1,SLC25A5,HSPD1,ZYX,SRSF7,SLC39A3,MRPS26,HNRNPD,HNRNPA1,DHX15,EGLN3,SRSF10,MRTO4,RPL9,RPL8,RPLP2,SSR1,DDX4,LUC7L3,TFB1M,AGO1,RPS15,RPL27,BAP1,DERL1,LSM12,MRPS16,UBE2H,IGF2BP1,NUDT1,CCNB1,SLC25A1,RAB2A,CARS1,RSL24D1,SF3B6,PHAX,RPSA,INSIG2,STRBP,HNRNPK,ATP1A2,PSMA5,RPL17,MEPCE,MAP1B,DHX9,RPL24,H2AC4,TRAPPC2L,AKAP8L,KPNA1,DPP4,GAPDH,CAND1,ALYREF,UBE2N,RPL32,MRPS9,SSBP1,PPT1,MAP2K1,CSNK1A1,TRMT112,MRPL12,EEF1G,FXR2,SRSF2,TRA2B,UFL1,RPS28,BMPR1A,DDX5,RAMAC,SF3B1,H2AZ2,MRPS25,CIRBP,COP1,HNRNPC,HNRNPAB,MYC,SNRPB,STAT1,MATR3,ESR2,RPL10,POLR2B,EIF4EBP3,LMBR1L,SMU1,TUBB4B,DCUN1D5,RPS23,SMARCB1,TRMT1L,RPS7,EEF2,RUVBL1,PSMA2,HNRNPF,TFG,CCAR1,RPS4X,LTO1,RPL31,EWSR1,DDX1,RAB5C,ASB1,RPL6,DDX50,DDRGK1,CTNNB1,SNRPD3,OSBP,RPS10,HNRNPL,DBR1,HSP90AB1,TRMT61A,FUBP3,DUSP6 |
| 1.592e-22 | -50.19 | RNF130 (ring finger protein 130) | protein interactions | 55819 | 322 | 173 | 19454 | 5460 |
CCT8,PDIA6,PSMA1,PSMA2,RAB8B,PTS,TMEM59,EEF2,RAB4A,RAB35,LAPTM4A,STX5,RAB1B,HNRNPL,RAB5C,PPIB,DDRGK1,DRG1,HSPB1,RAB5A,UBE2D3,RNF5,UFL1,EMC1,RER1,PSMB3,PAFAH1B1,PLAA,UBAC2,FDFT1,VDAC2,GGT7,PSMD4,ATP5F1B,TAGLN2,PSMD6,MANSC1,PSMB6,ALG5,MYC,PSMA4,PSMD1,UFD1,SPCS3,CKB,PSMD14,ZMPSTE24,SRPRB,CD1B,RDH11,FKBP8,TFRC,SURF4,PSMC3,EEF1B2,STT3A,CAMLG,COMT,UBE2G2,UBE2N,TMED9,VTI1B,DNAJC1,MIF,TMPO,LMAN1,CDC5L,DHRS7,GAPDH,TEX264,PGK1,HSPA5,SDCBP,FGFR1,SSR1,GSTP1,CHRNB2,PSMA6,PSMC5,SEC61A1,PITPNB,SGTA,ADRM1,PSMB2,TRIM32,UBE2E3,NDUFA4,ERP29,EMC8,RPS27A,PSMD12,SACM1L,FAF2,ERLIN2,RPN1,NME1,RAB6B,PLD3,PSMB5,PSMB4,TSPAN18,ERLIN1,PPIA,RAB11B,PDIA3,PSMD3,PRDX1,UBE2D1,CDK5RAP3,LYZ,ATP2C1,TXNL1,PSMA3,PSMC1,TMEM231,TOR1AIP2,PGRMC1,RAB6A,VAPB,ARF1,RAN,SEC61B,RBBP4,RAB11A,CNIH4,SCFD1,RAB1A,TSPAN17,EMC2,ARF4,PRDX4,CCDC47,CCT5,SELENOK,LBR,HACD3,SRPRA,PTPN1,HSD17B11,PSMB1,CALR,HM13,POR,ESYT1,PSMD7,RHOU,ORMDL1,SYVN1,RAB33B,SPCS2,TMUB1,PSMC4,SEC22B,UBA52,EDDM3B,CDK1,HSP90B1,STOM,STUB1,ENO1,GANAB,ACAT1,ALB,MSN,RAB14,UBB,CLRN2,TECR,SEC63,WDR83OS,CSK,USP14,SDF2L1 |
| 1.662e-22 | -50.15 | CDK9 (cyclin dependent kinase 9) | protein interactions | 1025 | 672 | 305 | 19454 | 5460 |
PPP1R10,CDC20,CSTF3,SRPK2,RPS3,PSPC1,ZNF330,PSMC5,CSNK2B,ATP1A1,IGF2BP1,UBE2H,SLC25A1,RPL7A,CFL1,RPS17,RPS15,MRPL41,EIF4E,HSPA5,MARS1,BANF1,NBN,EXOSC4,RPA2,FGFR1,SEPHS2,HEXIM1,ACACA,SPTBN1,GTF2H4,ING5,CCNH,FBXL19,RPS16,MYL12A,TMPO,CDC5L,SYNCRIP,AIP,EEF1B2,ALYREF,COMT,ADD1,DSTN,BCL10,SMAD4,SNRNP70,RPL24,LANCL2,RPS2,CDK12,MAP4,RPL10A,CSNK2A1,PPIL4,TPM3,GAPDH,NUP107,H3C1,HNRNPK,TMEM33,KPNA2,GSKIP,MEPCE,CAPZA1,RPL17,DHX9,CBX3,PIK3CA,DDX42,ARPC3,CAPZA2,RBM34,TAF2,NUPR1,IMP3,UBL4A,RPSA,TP53,H2AX,STAT1,TAGLN2,PSMD4,MATR3,ATP5F1B,PPP5C,ESR2,VDAC2,GTF2F1,CCT2,RBM27,FTSJ3,RPS26,RCL1,SERPINH1,MYC,OST4,CREBBP,HNRNPC,CCNQ,HNRNPA0,STAU1,RFC4,BMPR1A,CCNI,HSPA8,SF3B1,DDX5,STK26,EP300,NUFIP2,CKS2,CSNK1A1,RPL27A,IL6ST,MRPL12,RPS10,HNRNPL,ELK1,HSP90AB1,FUBP3,WDR82,CORO1C,AGR2,HSPB1,WWP2,RPL6,YWHAG,YWHAH,CTNNB1,KRAS,RUVBL1,RPL28,RPS4X,RPL31,CCT8,PABPC1,EWSR1,RUVBL2,RTCB,TUBB4B,PLS3,H2BC1,PDHA1,SMARCB1,RPL18,MOB3C,TOP3B,SUPT5H,TUBA1A,TRAF2,H1-3,RPS7,TMOD3,YES1,TUBA1B,CTTN,CTNNA1,HEXIM2,DTYMK,GANAB,TRIM24,MSN,RPS20,CDC73,SMAD2,AAMDC,CIAO1,RUNX1,ATP5F1A,AR,NONO,NPM3,SMC4,RPL4,RPA3,SIRT7,SQSTM1,TCEA1,ZMYM6,TOX4,PICALM,OXSR1,KRT7,RPL26L1,RPLP0,NOL7,ATG16L1,SF3A1,MYL12B,CCND1,SIPA1L1,CDK7,CCNA2,TOP1,CDK9,MDM2,CAV1,SRP14,AIFM1,SMAD3,RCHY1,NLRP1,MYBL2,RB1,MED21,FGR,NFKB1,HUWE1,RPS13,RNF20,ARF4,FBXO25,PPP1R12A,SFXN1,TCOF1,RPL23A,SEPTIN7,HINT1,TMEM94,ILF2,CASK,TBK1,CCT5,MAP2K3,DDX39A,LBR,EEF1A1,SMAD1,RPL15,PRDX2,ACTB,TUBB,CPSF1,UBE2S,RAN,PELO,CDC7,SNRPD2,RPS9,LMNB1,BRCA1,RPS5,HSP90AA1,RNF40,RBM15B,IL1B,IL1A,CSRP1,COIL,FTL,SKP1,UNC45A,G3BP2,RMND5B,MFAP1,MYL6,SLC25A3,ACTL6A,IDH3B,OCRL,CCAR2,RPL7,SPTAN1,EGLN3,PPIA,NUP35,DNM2,FBXO32,KRT8,RPLP1,HP1BP3,AHSA1,HNRNPD,RPL23,TAF7,PRDX1,NDC80,ATG7,HNRNPA1,LASP1,S100A10,UBE2A,MSL2,RAD21,SSRP1,RFC3,SLC25A5,HSPD1,NDUFA4,HNRNPA2B1,FAM76B,SRSF7,RPN1,EXOSC3,RPS11,POLR2C,CDK5R1,SNRPE,SART3,PPP2R1A,GFPT1,ACTN4,TULP3 |
| 1.687e-22 | -50.13 | CUL1 (cullin 1) | protein interactions | 8454 | 838 | 364 | 19454 | 5460 |
ACTA2,SMAD3,RPL12,MRPS23,MDM2,NCBP2,CDK9,RPL35A,DCUN1D1,SPATS2L,GRSF1,H2AC14,EID1,CCNY,RPL23A,NKRF,FAF1,PPP1R12A,FARSA,SOX9,PDE6D,POLR3H,RPS12,ENO1,CCNF,VIRMA,RHOJ,RACGAP1,BRAP,FBXO7,CDC73,RPA3,DVL2,BRIX1,FBXW7,NF2,SLC7A9,CCNA2,RARS1,HNRNPH3,RPL26L1,UBE2F,RPLP2,PSMB4,PSMB5,RPL8,RPL9,DHX15,TMEM237,PPIA,SNX18,HNRNPA1,HNRNPD,MRPS26,SRSF7,PCNA,HNRNPA2B1,NUDT5,HSPD1,SLC25A5,COPS4,SSRP1,PSMD12,ASF1A,FAF2,ZNF704,CKS1B,RAF1,SNRPE,RPS11,RPS9,SNRPD2,SNRPD1,ENO2,TUBB,ACTB,PRDX2,TMEM183A,ILK,NLRP3,PFDN2,HSP90AA1,RPS5,YWHAZ,SENP8,PSMA3,FBXO30,CDKN1A,RAC2,RPL32,ALYREF,RPRM,SSBP1,MXI1,CAND1,FZR1,GAPDH,KPNA1,AKAP8L,H2AC4,RPL24,DHX9,TGFBR2,HNRNPK,NEDD8,PDE12,PSMA5,RPSA,TP53,COMMD8,STRBP,CBX3,RCBTB1,CDC20,FBXO44,CFL1,NUDT1,AKT1,IGF2BP1,UBE2E3,DLAT,IRF3,PML,RPL27,CLU,UGP2,OIP5,RPS15,FBXL19,CDC42,KLF4,LUC7L3,SWAP70,GYS1,HSP90AB1,SNRPD3,HNRNPL,RPS10,CTNNB1,RPL6,WWP2,DDX1,DRG2,MYO1B,EWSR1,TRIM21,RPL31,FBXO3,TFG,RPS4X,RUVBL1,PSMA2,HNRNPF,PSMA1,EEF2,RPS7,RPS23,DCUN1D5,GHR,BTG1,TUBB4B,FBXL14,PSMB6,MATR3,STAT2,BAG3,SNRPB,HNRNPAB,HNRNPC,PSMA4,MYC,CRMP1,COP1,FBXW11,CKB,CCT2,CIRBP,DDX5,SF3B1,RPS28,EEF1G,TRA2B,SRSF2,MRPL12,PSMB3,PWP2,SEC23A,CDCA3,AIFM1,SRP14,TOP1,PRNP,HDAC6,NFKB1,FBXO34,CRBN,SLC6A3,HSD17B10,SNRPG,FBXO25,RPS13,SEM1,RPL15,EEF1A1,MRPL11,TBK1,FBXO8,MRPL49,ILF2,RPS20,PTEN,ACAT1,RTRAF,EIF4A3,RPL22,RPL13A,MMD,TXN,PPP1CC,ATP5F1A,CA2,LGALS8,CCDC22,SQSTM1,FBXO9,MBD3,RPL4,CCND1,MYL12B,RPS14,RPLP0,HSP90B1,CDK1,LMNA,HP1BP3,RPLP1,COPS2,FBXO32,LRWD1,CACYBP,SPTAN1,COPS7B,PRDX1,CLPX,PRPF19,RPL23,CDKN1B,RPS24,PPAN,AKT2,RFC2,SRSF4,G3BP1,DCUN1D3,GFI1,TPD52,RBPJ,FBXL3,EZH2,RPL37A,FAU,RPL19,SNRPB2,RPL7L1,RPL35,DYNLL1,CUL3,CUL2,TAFAZZIN,CRY1,FBXW4,G3BP2,SKP1,FBXL4,NSFL1C,PRDX3,TIMM13,MYL6,RNF7,MCL1,CD274,EEF1B2,SYNCRIP,SDHB,CDC5L,RPS16,COPS5,KARS1,RPL10A,RPS2,SNRNP70,RPL3,KPNA2,ACTR1A,CDK4,SGTA,PSMA6,RPS3,TRAF1,RPL10L,PCBD1,RPS17,TIA1,AKT3,PSMG3,PTTG1,KCNMA1,DNAJC10,RNF113A,PRDX6,HNRNPH2,MARS1,HSPA5,H2AC13,CFTR,SPTBN1,UBE2M,BTG2,RPA2,RPRD1B,EED,SRSF1,FBXO31,RXRG,LYAR,FAM98A,CENPW,AGR2,IKBKB,PDIA6,RTCB,RUVBL2,FBXO11,CCT8,RBM3,PABPC1,PAEP,HNRNPDL,MAGEC2,RPL28,KRAS,TRAF2,FBXL7,KLHL12,RPL18,SF3B4,NFKBIA,NFKBIB,FBXO22,PSMD4,NUDT7,COPS7A,POLR1B,FTSJ3,H1-10,POMP,EP300,DDIT3,HSPA8,SNRPA,STAU1,HNRNPA0,FBXO42,RPL27A |
| 3.102e-22 | -49.52 | HDAC6 (histone deacetylase 6) | protein interactions | 10013 | 915 | 390 | 19454 | 5460 |
CDC42,CSNK1G3,RPL27,NBN,PML,PGK1,DLAT,RPS15,PSMB2,SLC25A1,AKT1,RPL7A,CFL1,CEP70,OAT,IGF2BP1,UBE2H,PSPC1,GNAO1,PTPMT1,CDC20,RPSA,PIK3CA,CAPZA2,BIRC5,GNAI3,MYD88,DHX9,H3C1,NEDD8,AKAP12,HNRNPK,CSE1L,RPL17,TPM3,GAPDH,H2AC4,RPL24,KPNA1,MAP4,ACSL4,SSBP1,RPL32,RAP1B,ADD1,CPNE1,SYK,ACAA2,EIF4B,BOLA3,CD40,DDX39B,SPECC1L,RPS28,DDX5,FXR2,ADRB2,PHB2,EEF1G,PACSIN3,MYC,LDHB,HNRNPAB,PSMD1,SNRPB,BAG3,CCT2,CKB,RPS26,VDAC2,DLST,RRAS2,CLXN,MATR3,APEX1,NCKAP1,RPL10,ESR2,TUBA1A,H1-3,RPS7,EEF2,TUBB4B,PDHA1,RPS23,GNAQ,RPL31,GNA11,TRIM21,EWSR1,MYO1B,HNRNPF,RUVBL1,KGD4,RPS4X,RPL6,XPO1,DNTTIP1,CTNNB1,AK2,DDX1,RAB35,RAB1B,RPS10,SNRPD3,CCT7,HSP90AB1,SF3A1,STOM,PICALM,KRT7,RARS1,SOD1,PDHB,BRIX1,RALB,CNTNAP1,RPL26,AP2A1,MAPRE1,SLX1A,TUBA1B,CTTN,ENO1,TRIM27,RPS12,ALB,MSN,TMOD3,CTTNBP2NL,UBB,VIRMA,GNAI2,FBP1,CCT5,FNTB,ACTR2,ALPL,PPP1R12A,RPL23A,IGF1R,PTGES,FARSA,RIGI,GRSF1,PROM1,NME2,OSBPL8,PTPN1,RPL12,MRPS23,CDKN1A,SLC25A3,RP2,SRM,CSRP1,RPS29,YWHAZ,RPS5,BAX,HSP90AA1,NLRP3,GNG12,S100A6,RPS9,PRDX2,ACTB,LGALS3,TUBB,ERH,JAK2,ACTN4,RPL29,RPN1,BZW2,RPS11,SLC25A5,HSPD1,HNRNPA2B1,PCNA,MKLN1,SRSF7,ZBTB16,S100A10,RPS27A,IMMP2L,FLOT1,SSRP1,PDIA3,HNRNPA1,HNRNPD,RPL9,RPL8,KRT8,RPLP2,PPIA,SLMAP,DHX15,SPTBN1,SUMO1,CFTR,UBE2M,GSTP1,PRKCA,UTP15,BANF1,PRDX6,KDM1A,HSPA5,NAA50,PTPN11,RPS17,SPOP,ATP1A1,RPS3,LIG3,PSMC5,EIF2S2,BUB3,RALA,ACTR1A,ZMYM3,TFRC,ARPC3,SLC25A11,RPL3,CAPZA1,H2BC14,KARS1,PGAM1,SMAD4,RPS2,RPL10A,SYNCRIP,EEF1B2,IFRD2,RPS16,TMPO,RPL27A,PAFAH1B1,CD59,PLAA,PIH1D1,RFC4,XRCC5,HSPA8,DDIT3,EP300,RAP2A,UBE2D3,HNRNPA0,GNB4,MEF2B,BRMS1,LAMTOR1,H1-10,FTSJ3,DNAJB6,POLR1B,EFHD2,BST2,ATP5F1B,PSMD6,DES,ISG15,KIF2A,TPPP,HDAC11,RPL18,PABPC1,CCT8,FBXO11,RUVBL2,PDIA6,RPL28,GSTM3,DIRAS2,PPIB,STK4,HSPB1,SRSF1,CORO1C,FAM98A,EIF2S1,TCP1,RPS14,MYL12B,LPXN,LMNA,CDK1,JUP,HSP90B1,RPLP0,SQSTM1,ARPC2,H2BC12,EIF5B,RPL4,POLDIP2,ATP5F1A,NONO,TUFM,PPP1CC,STK24,LGALS8,XPOT,EPHA2,STUB1,GANAB,GSK3A,PTEN,RPS20,LDHA,YES1,RPL13A,TECR,RPL22,LBR,EEF1A1,RPL15,ILF2,RAD23B,SLC25A10,SEPTIN7,HSD17B10,SNAP23,RPS13,CTNND1,ARF4,MSH6,PRDX4,HDAC6,CRBN,ETV6,SRPRA,PPP1R18,PRNP,TOP1,DBT,G6PD,CAV1,H1-5,ATP5PO,MYL6,HADHA,NUP50,GPC1,PSMC1,POLA2,UNC45A,G3BP2,CUL3,MCM3,TBC1D16,MYO6,FAU,APOBEC3G,CPSF1,RAN,PELO,AP2M1,RPL35,RBBP4,DYNLL1,GNB1,RPL19,GFPT1,SAP30,AP2S1,OTULIN,ATF3,RPS24,G3BP1,EMP2,LASP1,HS2ST1,PRDX1,SAV1,UBE2D1,HBA1,CDH13,AHSA1,RPL23,FOLR1,PHB1,RPLP1,NYAP2,SPTAN1,RPL7,CCAR2 |
| 3.443e-22 | -49.42 | LRPPRC (leucine rich pentatricopeptide repeat containing) | protein interactions | 10128 | 801 | 350 | 19454 | 5460 |
AUH,MTG2,PYCR1,PMPCA,MIR98,YWHAZ,HSP90AA1,MIR363,SNRPD2,MRPL23,MIRLET7D,NDUFAF4,CDKN1A,PSMB7,ARMCX3,EXD2,TRIM5,HSCB,DUSP26,PIK3R1,MTRF1,MAP1S,HNRNPA1,MRPL18,MRPS26,MIR7-2,ATP6V1A,EGLN3,RAF1,HSDL2,B3GNT2,PPP2R1A,NDUFS6,CHMP4C,SART3,HSPD1,THNSL1,HINT2,MRPS11,PSMD12,RAD21,AHCYL1,IMMP2L,HMOX2,DNAJC19,GAB1,CCNF,MRPL53,MGST3,VIRMA,TIMMDC1,UQCRC1,GABARAPL2,METTL14,RARS1,HAUS2,WTAP,RPA3,IDH3A,MIR205,MIRLET7I,MIR34C,MRPL17,FBXW7,MIR7-3,MRPL20,GRSF1,MOV10,LAMTOR2,POR,DNAJC4,MIR34A,MIR25,MRPL50,PTP4A3,MRPL24,MRPS23,FBP1,NDUFA2,AURKAIP1,MIR15A,NDUFS3,RAB1A,SFXN1,DNAJC30,VTA1,MRPS18C,FASTKD5,PTGES3,RIGI,MYC,HNRNPAB,ATG101,BTF3,PSMD1,MRPS25,FBXW11,PSMD14,VDAC2,LMBR1L,DLST,MTG1,PRMT5,MIRLET7B,MRPL13,MATR3,ESR2,DUSP14,ZC3H14,EDEM3,MRPL12,PPT1,NGRN,NDUFS2,UFL1,ADRB2,PHB2,NDUFV2,CTNNB1,DDRGK1,MIR31,PEX3,MIR221,DUSP6,RPS10,HNRNPL,MIR9-1,HSP90AB1,ETFB,MIR222,PDHA1,NDUFA12,MIR9-2,MIR206,HNRNPF,PSMA1,KGD4,RUVBL1,SLC25A1,NDUFAF2,VAMP5,MRPS16,IGF2BP1,UBE2H,UQCRC2,PTPMT1,PPP2R5E,MIR34B,MIR7-1,CYC1,BAP1,PML,DLAT,DERL1,GFM1,NME4,METTL22,COX5A,LYPLAL1,TPM3,TMEM70,CHCHD1,H2AC4,TRMT5,MAP4,MRPS9,SSBP1,MGME1,FZR1,MIRLET7G,MIR429,LMAN1,MYL12A,ATP5PB,TP53,METTL15,CAPZA2,MAP1B,MRPL52,CLPB,DHX9,MIR9-3,MRPS33,MEPCE,MIRLET7C,CUL3,TOMM40,RIT1,RBBP4,PARL,TIMM29,PPARG,NDUFA5,ATP5IF1,CRY1,HADHA,COIL,PSMC1,MIR106A,SKP1,CLPX,PSMD3,HEBP2,STOML2,MRPS35,RHOG,PSMD10,MIR1-1,PHB1,MIR141,GATD3,CCAR2,NDUFS8,FEN1,E2F4,LGR4,EZH2,NGB,COX8A,RBBP7,EMC8,ETFA,MRPS17,PYCR2,TUFM,MIR145,IVNS1ABP,STK24,NAPA,MIR16-1,PTEN,ACAT1,MIR1-2,JUP,MRPS34,HSP90B1,GRM2,MTRES1,SIRT7,PRPF4,SMC4,AATF,CRYZ,POLDIP2,NFKB1,EMC4,HDAC6,AIFM1,MIR106B,SEC23A,ARF6,DBT,SLC25A12,CCDC47,MRPL11,PPIF,MIR200C,BCS1L,MIR17,MIR20A,MRPL49,HAPSTR1,HSD17B10,EMC2,LSM4,DUSP21,FBXO25,MRPL22,POLR1B,TACO1,CCDC90B,NFKBIB,ATP5F1B,PSMD6,NDUFAF3,MRPS18A,PIH1D1,HSPA8,HDAC5,AKAP1,STAU1,MRPS7,MIR143,MRPL9,MIR29C,IKBKB,AGR2,MIR140,CORO1C,MIR214,UQCRH,RMND1,ARFGEF1,MTA2,PABPC1,RUVBL2,RPAP3,KRAS,MIR155,HNRNPDL,PTPN11,GSTK1,SPOP,RC3H2,ATP1A1,ZNF330,MRPS28,PSMC5,KCTD9,MRPS21,ADRM1,SMURF1,DUSP3,SPTBN1,MRPL10,CFTR,RPA2,QRSL1,HEXIM1,UBE2M,MIR21,ACACA,MIR10B,TWNK,MRPL41,MRPL40,MIR29A,MIR107,HSPA5,KARS1,BECN1,USP15,COQ8A,CD274,SDHB,COMT,COX4I1,CD4,TMPO,MRPL47,HADH,DUSP1,GFM2,RNF8,PSMC3,MIR200A,ATP5PF,MRPS18B,KPNA2,MIR16-2 |
| 3.515e-22 | -49.40 | large_cell | COSMIC cancer mutations | large_cell | 14845 | 4442 | 16828 | 4835 |
NCKAP1,NRP1,CDK5R1,CNIH4,GLUL,LMO4,CLU,KIAA0232,ATPAF2,CCR6,TAAR1,ZMYND19,SLAMF9,XAGE5,ZNF397,APOBEC3A,SEC14L1,ZNF319,ID4,UBE2A,ARMCX1,ATP6V0E1,UBE2D3,CCT2,NHP2,TRIM23,NAIF1,STRBP,ING1,IRF1,CASK,GAL3ST1,LTBR,GRPEL1,ELMO1,TCP11L2,PRPSAP1,GABARAP,FGFR1OP2,SLC35A1,DHRS4,MEF2A,IMMP2L,RAG1,ENY2,KLK3,SLC30A5,SNAPIN,ZNF304,MRPL24,MRPL50,SLC38A9,IL15RA,FAM78A,PPP1R2,MIOS,RMND1,CTNNBL1,GRM2,CYP11B1,IDH3B,SENP5,JAKMIP1,ADGB,GPAA1,TLR3,NCR3,EIF4H,ITK,FAM8A1,SWAP70,MYL12A,HSD11B1,CYP39A1,GNRH2,CHDH,DKK3,IL20RB,SF3B4,DPP10,PRRC2A,CRABP2,CDO1,PPIL4,RAB11A,CCNI,TLR9,SNX20,WDR38,FIBIN,L1CAM,AKT1,DLX1,FGD2,APEH,COMTD1,FNDC8,CCDC69,PSMA3,SOCS5,AK2,GALNT1,GSTO1,TMEM156,MGP,MDM2,EHBP1,MRPL13,UST,EXOC8,PFDN5,TOM1L2,GNRHR2,LYAR,B9D1,NUDT3,CNP,RND3,KLK9,PLA2G5,DOK4,ARHGAP1,RNF141,KLHDC8B,TRIM32,PRIM2,SNRNP27,CD99L2,PDIA6,UBR7,SDR42E1,GPR89A,EFCAB7,EXOSC1,ZMPSTE24,E2F6,GFM2,GDI2,MRPL23,ZNF207,EDF1,TMEM219,ATP6V0B,TMUB1,TRIM3,C1QC,POLR3H,SLC25A31,ZNF671,SLC17A5,LIG3,RPS14,LYPLA1,MEAF6,UGCG,SBK2,SORD,PSMB5,MCOLN1,CCT5,ENPP4,ANAPC2,FBXO32,AGK,PRPF4,ZNF593,ARMCX5,RAB18,FKBP14,IDH2,AGER,CD58,IMPACT,SRP54,TMX4,BUD31,CAMK2G,PRMT2,TACR3,CIB3,RPL15,TUBG1,CACNB4,GHITM,SCFD1,TTC4,CCDC47,PYGM,SHC1,FGFR1,HCRT,CAMK2N1,CD200R1,CRYGB,KCNJ11,PPP3CA,FAM89B,RCVRN,PEX3,CCDC127,RFX4,FRMD8,ADRB1,PKNOX1,ZDHHC14,RBM17,PCDHB8,HEY2,TRAPPC1,CLDN11,NIPA2,RABL2B,FAM199X,LRP12,NPY2R,RNASET2,SLC35E3,SPTAN1,HNRNPC,SETD5,PTPN1,TRIM37,HECW1,ZBTB38,NFIL3,PGS1,SLC25A21,RBBP7,RMND5B,ARMCX2,SIX5,TRIM21,ACTA2,PPARG,GALNT12,ARFIP1,SPR,AZIN1,PSME2,HBE1,ABCB1,INO80C,AZGP1,FGF1,JAK1,LBH,GTF2E2,MLF1,MAGOH,NKX3-2,TBC1D10C,CCL19,DHRS3,DEFB116,TNFAIP8L2,NDST1,KTI12,SMAP2,RAB3B,CDCA3,ATP6V1G1,MTPN,WDR77,MEST,FZD4,AAMP,SYN3,ZCCHC10,MX2,GPBP1L1,MFSD6L,LYG2,ZNF24,FBXO42,TMEM215,SERPINB10,TSEN54,LHX2,CDC73,UBAP1,ZYX,CYP27A1,DYNC1I2,S100A6,BTF3,MMP9,ROPN1B,VRK1,PGK1,HEBP1,SLC7A9,ALKBH4,MYH2,SNAP91,DNAJC5,TMIGD1,CSNK2A1,PIWIL4,KPNA1,RARRES2,CTNNBIP1,GNG7,ATF4,KBTBD2,GSTO2,SUPT7L,JOSD1,AFTPH,LSM3,RS1,KIT,PGBD2,SIPA1L1,STAMBPL1,ZKSCAN1,CLDN14,HSPE1,RPL37A,SERPINH1,TRA2B,SOX21,RAB4A,DHX16,LEAP2,HADHA,LHFPL1,KCNA2,HSPB1,B4GALT6,GXYLT1,NUDT16,XPOT,FRA10AC1,PDIA3,APH1A,NDUFB8,ISYNA1,NAA11,EIF1AD,STX17,LEPR,WNT7A,MSX2,RPRML,NLE1,KRR1,SNAI3,CDC37L1,PELI3,FGF17,HBB,CXCR1,NEDD8,PTCRA,TRMT6,NDUFA5,CCL21,KCND2,DFFA,IL34,LPXN,RASGRP2,ST13,POLR2I,CD2,FBXO30,TIGD7,RABAC1,WWP2,RAP1A,UCKL1,ACAA2,BRMS1,CD3G,CDKL2,CHRNA7,GAS8,KIF1C,TAC1,AKR1C2,NPVF,IGFBP4,LMBR1L,SPATA2L,TBCE,IPP,NQO1,BRI3,HEXA,ADAT1,TMED1,RBM23,EXOC2,XPO1,EFHC1,SLC25A32,GJA10,THRAP3,EEF2,CREB3,RNF103,TF,INTS10,SURF4,XPO5,RNF187,APOBEC3C,GPR162,ZNF513,SLC7A4,ZMYND11,PCDHA5,SLC20A2,UBXN10,NUBP2,PFDN6,LDHA,PRCC,GSK3A,THOC1,ABCC5,RANGRF,NUDT19,RC3H2,ATP2C1,FATE1,DNAL4,GNMT,CCL25,AQP4,CREBL2,TXNIP,GLE1,WDR37,EIF4EBP3,ZSCAN1,FURIN,DHX9,SLC39A9,PSMD6,IL23A,GALE,SH3GLB2,EIF2B5,CIRBP,ENDOD1,CXXC5,SPOCK1,LASP1,PHKG1,NEK7,UTS2R,GTF2A1,WBP2,FUT8,SETD4,LCN6,COX7A1,FBXO9,TMED3,ACOT13,WFDC13,CCND1,OR2W1,RPGRIP1L,KLF10,MPHOSPH10,MRPL47,S100PBP,TMEM33,AP3S2,SCG2,ARHGAP21,RHCG,SPINK13,FAF2,BMPR1A,CETN3,URM1,CACYBP,CTSK,MTAP,RAB3C,PWP2,TOLLIP,BATF,DUSP1,TGFB1I1,STX8,FAM200A,S100A10,NFYA,CPT2,CHST9,ANP32B,AP1G2,NDNF,DEK,NLGN2,CYP4F8,PRKD3,SLC5A6,SPEF1,SCAMP2,CD164,CDKN3,BPGM,PPIB,MRPS25,RBCK1,NFE2L1,SPATS2L,NOP58,AKR1A1,FABP5,MRGPRX4,PGAP2,CTSD,INPPL1,BACH1,MIA2,KIF2A,SLC35A2,ENTPD4,ARMC8,ID1,PTDSS1,CYC1,POU1F1,FCAR,NPTN,CCDC42,CRYBA2,DEGS1,H19,SPRED1,NONO,POLL,ALDH1L1,MAK16,TSSC4,EIF4EBP2,OR2A2,HPCA,SV2B,TCP11L1,SOST,GPR37L1,NDUFAF2,SNAPC1,SNTA1,SIVA1,GFOD1,TNFAIP3,ABHD16B,RAP2B,MTMR12,DUOXA2,TRAF7,MMACHC,IQSEC1,NOL4,FYTTD1,SIRT7,RRAGA,ETV6,TAPBPL,CWF19L1,CDK6,ESR2,DCAF5,ADCY3,SNRPD2,CLEC12B,SFTPD,INTS12,SOCS2,CYP2D6,CTNNB1,RAB8B,PROX1,FGF13,PRKX,LSM6,ZMAT5,RTP4,SYNGR1,NAB1,ENPEP,CERK,USP39,SLPI,USP38,ZNF174,DNAJC8,TNFSF18,PPDPF,RNF167,FAM107A,CRYGD,RAB33A,SPTBN1,TNRC6C,RNASEL,CHI3L1,UTP23,FERMT2,TOMM40L,EIF3J,GNPNAT1,GIMAP2,WWP1,CBLN4,RHOJ,HIRA,S100A8,CD47,IFNG,JUN,TMEM50B,CCR3,ZNF687,SUMO3,OPHN1,PTGER1,SFT2D2,CMAS,RAB23,CCL8,CAPZA2,SLC35E1,RB1CC1,TPPP,RFTN2,PPID,YPEL5,ATP6V1C1,GGCT,RCBTB1,HNRNPA2B1,MAPK1IP1L,PLA2G15,STX6,OR2A25,FANCG,HNRNPK,PRKAG1,NFKB1,MAFG,SCD5,ACAP2,LHFPL2,FOS,DYRK2,CLDN22,EGLN3,RPL26,POMP,RIOK2,MRPS28,SLC7A14,DDX42,ATP1A2,PXMP2,MT2A,PPP1R16A,CYB561D2,GMPPA,RPL6,TUSC3,ADAMTS1,CXCL14,CLDN8,BNIP3L,RNF122,KIAA0408,SERPINA5,CREB1,BICD2,FMO2,TMEM177,SQSTM1,GLIPR1,RAN,RPP25,RBM12,HAND2,PGR,BRD9,POLR3B,NPY5R,CXCR4,HSPA14,GTF2F2,DLG4,KIAA1191,CCL17,KCNH1,KCNK10,SLCO1A2,SELENOS,TMCC2,ZNF609,GJB2,WDR3,MANSC1,PLEKHA8,KRT7,TMEM106C,SRP14,ACTR2,PTRH2,FOXS1,TAS2R5,TMEM203,CRYBB3,TMEM164,SYNJ2BP,ACP6,SESN2,PLAGL1,TRAM1L1,RFXANK,KLHL15,GCA,ZNF576,ISCA2,UPF3B,RABL3,EHD1,CHST1,FCHO2,MPV17,TRAM2,PPP1CB,AMY2B,NDE1,RBMX2,CD2BP2,TDRD7,HMBS,CCDC65,LDHAL6B,SLC4A8,SNIP1,UBE2D1,LY6G5C,FAM168A,ACTL6B,RPAP2,INHA,RGS5,RAB1B,HRH3,ABHD13,ZBTB45,PIWIL2,SOS2,AKIP1,GYS1,SLC23A2,ROGDI,PGM2L1,GK2,CDKN1A,FOXN2,RBFOX2,SLITRK2,STX18,ELSPBP1,CLIC2,MED11,SDHAF2,PPFIA3,TMEM14A,GDE1,GPX5,PCGF3,CPSF2,CDH8,PNPLA8,MYEF2,TAF5L,MOV10,NGB,GLT8D1,UQCR11,ZCCHC9,SLC43A2,TMEM91,HIGD2A,B3GNT2,TEX12,TOP3B,FLYWCH2,LRRC24,GRIA2,MRGPRX2,DDX4,CAB39,LIX1,KLK5,PHYHIP,DYRK1B,FN3KRP,WIF1,ISG15,ACADSB,SNX24,STAT6,FGFBP2,EZH2,ARCN1,KCNIP3,INPP4A,AMT,RAB9B,SACM1L,VPS33A,CD226,CRBN,ZFP1,PDYN,B4GALT3,SNRPA,CMPK1,BEND5,VAMP2,CCNF,TRAPPC6B,GPIHBP1,WDR44,RAB2A,CTNNA1,TIMM10,STK38,WEE2,PNP,RAB5C,PCDH19,AP1AR,FOLR1,SLC6A11,RAB37,C1QL1,CSTF2T,PSRC1,IFI35,FBXO25,CAV2,DERL2,TXNL1,TIMP1,MLF2,PLEKHJ1,LYNX1,RPL23A,TMEM59,IL6ST,EIF4B,PPP2R1A,SMAD3,PTHLH,MRTO4,SLC25A4,EWSR1,B9D2,TMEM204,PROS1,ABHD14B,MRPS16,EED,ZNF592,MTRF1,CIB2,MRFAP1L1,TGFB3,ACSL4,TRIM24,YAF2,ELP3,CALHM2,ADO,GMPPB,LMNB1,BECN1,TES,CCDC25,CHMP2A,EMP3,HSPA8,MSMP,CBR4,SLC19A2,VMP1,GOLGA7B,TSPO2,SH3GLB1,THTPA,PREPL,EFNB1,RNF113A,DEFB114,MT1M,IFNA10,TFE3,COMMD8,PELP1,ITGA6,CSNK1A1,RTKN,NTN4,PHYH,FUT9,IL10,UBE2V2,RPLP0,TSPAN5,OR10G9,BZW2,RINT1,NAT2,KHDC1,SPECC1L,EIF3K,CREB3L4,B3GALNT1,CD274,FABP7,BCAP29,ZBTB17,RAB40AL,DDX39A,SSU72,AKAP12,IGBP1,SNCG,BLOC1S2,SNAPC3,CDKN2C,COX4I2,LHFPL4,TRIM5,EIF4E,TMSB4X,RAC2,LCA5,STK24,MRPS21,PYROXD2,TAS2R40,LRP6,PARP11,SLC32A1,POR,ST3GAL5,IFRD2,CEP97,ZNF501,IL18,DERL1,ST3GAL1,SOX2,CSNK1A1L,PCMTD2,KLC2,STXBP1,PAX9,IRF3,MTHFD2L,DPEP1,UQCRH,PRKAB1,STAU1,STOML3,TSN,SERINC3,SLC41A3,FKTN,KLK6,TMED7,DNAJC3,RNASEH1,KCNMA1,NOS1AP,BCL10,MBD5,PDHA1,ADPRH,DUSP19,NME1,STMN2,RGS2,DPY30,CNNM4,NR1I2,NPR2,CDK4,KCNK13,TRAF2,RBM7,PCDHB1,ABHD4,BRCA1,KDM4B,TMEM184B,ZNF287,ACAT1,GIT2,NKIRAS1,GTF2B,CXCL3,SDF2L1,RUVBL1,RAB3D,SLC13A5,LAMB2,CLDN4,GPX6,POPDC2,GREM2,TGIF2,RDH10,PRPF19,CREBBP,LDOC1,PDCD4,GPAM,HTR1F,TRIM54,RPLP2,CDC42SE2,FAM98A,ACBD7,ANKRA2,ADIPOQ,ALKBH5,ERH,UHMK1,LCP2,CRTAP,METTL2A,CLDN1,ABHD6,TFCP2,AKAP14,NDUFAF4,CRYBB2,FAM162A,CCNB1,CTDSP1,SLC35D1,SMU1,RMI2,COL1A2,SAT1,R3HCC1,CSGALNACT1,VAMP5,METTL14,EDEM1,GNG2,AMIGO1,JPH4,PTS,TOR2A,GTF2H2,MAP3K11,MBL2,ATAT1,ARMC7,CIDEB,IPO8,TMSB10,ZBTB5,AIF1L,ZC3H7A,DSTYK,TMEM123,FUNDC2,MRPS23,CSRNP1,ZNF862,SYP,ATG4A,SFRP4,CDKN2AIP,RGS7BP,FCN2,RER1,ISG20L2,GPHN,POLE4,HSP90AB1,SEC61B,GPR65,BCL7B,TOM1,EIF2B3,DNAJC22,TMX3,HTR5A,TCF23,GBE1,CHGA,APOO,SNX17,BCS1L,GPR137,NRSN2,TOP1,TMEM144,GCNT3,NKX3-1,F9,CYP2C18,NDUFS8,MYO6,RPL27,PPP1R1A,MSTN,PRICKLE2,MTF1,PTH2,DIO1,SLC16A10,VGLL2,SLC35F2,SYNCRIP,TRMT112,CLDN9,KIAA0513,CCNH,SEMG2,POLA2,UBASH3B,MNS1,POLB,CSH1,UBL5,BTN2A2,IFNB1,ABCG2,LTA,MRPS9,FAM83C,TOR1B,SPSB3,STUB1,PIP4K2C,KLF9,TMEM41A,IL1R2,ACVR1C,NKIRAS2,FAM181B,SNRK,TEX264,ST7,AVPR1B,TRAK2,GSTA1,UBLCP1,SRSF2,SERPINB1,DDX50,GTF2H5,RPRD1A,SLC25A10,VRTN,HINT3,ZNF821,PLS3,ST8SIA5,CYP1A1,TNKS,SLC22A17,STK4,PPP2R2C,BST2,ACBD6,RNF34,COPS7B,DENND2D,KLF4,ETF1,LRRC8B,TRIM68,ATG7,PREB,NPW,NFKBIA,TUSC1,PRDX1,FAM53B,TAF10,DHRS13,PARL,POLR2B,TSNAX,LRRC61,UBIAD1,GTDC1,ATP6V1A,EGFL7,TMEM59L,HLF,ACP5,SERPINC1,REG1B,GPM6B,FBXO22,SLC7A8,RFC3,VEGFA,FAF1,IQCK,TP53INP1,DECR2,AVL9,DTWD1,SMPD2,ATXN10,ASTN1,TBC1D13,SOD1,NCBP2,REN,CCR1,GNPDA2,TMOD2,SOBP,PTPN11,NAPA,NOTCH2,CRAT,TM4SF19,SLC25A12,HMGCS1,AK3,CLCN6,USP16,TCEAL1,PFDN2,LTB,TMED5,HARBI1,SHOC2,HDHD3,PSMA1,RPL32,DDRGK1,CDCA7L,MRPL22,SS18,CD1C,UMPS,RAB19,NUDT7,IFIH1,FCGR2B,MTM1,BIRC2,EPS8,RFXAP,HOXC4,UPK1A,SIAH2,CHCHD6,CER1,POLR1B,MCM4,SCNM1,DCTD,FAM177A1,STARD4,THOC2,FLOT1,DROSHA,NR2E1,KLHL22,MAVS,UBP1,IGF1R,CX3CR1,SLCO2B1,SOX14,PDAP1,CHMP4C,KLF1,CLPB,VDAC1,FEN1,ASB7,PRKACB,GLRX2,APOBEC3H,LANCL2,ADD1,CBR3,CLEC2B,CCNY,CHKB,ELF5,PKP4,GPR176,CLDN12,SCML2,VGLL4,DNAJC19,ERAS,GSTM5,PLEKHO1,MYBL2,ZNF326,CRHBP,CNOT2,HSD17B6,APOBEC3F,PLCB2,MAP2K1,LRRC3B,FPGT,FEZ1,PRDM4,EIF4A2,MAGEH1,STAT5A,COPS5,ADAMTS10,EP300,RNF8,PEA15,LAMP2,FAM43A,NLRP9,RNASE1,TMEM45A,CCL2,LLPH,GSTP1,PPM1K,OR8B12,IFI6,AR,EFNA3,SNRPB,TPM3,SSR2,MORC2,ELOVL1,SOSTDC1,RIT1,CHRNB2,GPX7,PTPN4,HP,STOM,CTTN,CLLU1,RPL23,SPIN3,RABGGTB,FBXO7,SLC2A3,SEMA4C,ASZ1,METTL22,CYP2C8,CAPN1,USP3,TGFBR2,CDNF,TNFRSF1B,TIMP3,PPP3R2,PRSS12,PRMT6,PMM2,TTL,MPDU1,VAMP8,TMEM70,IL2RA,PPAN,RCL1,PPP2CB,GABPA,KLHL24,FKBP8,CHST13,ZNRF1,SMAD1,AQP2,CLEC18A,FBXL14,RHEB,DHX15,PSMD4,NPPC,RPS7,RAB27A,GRAP2,TRIM15,RELL2,SLC6A6,TCF19,SLC30A7,CCDC134,PDHB,DDX46,ZNF664,MAT2B,MLC1,BBS5,XCL1,TSPAN18,RPS6KA4,GANAB,LARP4B,STX11,SERPINA1,PMP22,MRPL11,SCLT1,DAAM1,LRRTM3,ANKRD34B,HSPA13,LMAN1,NPSR1,UBB,SH2D1A,SLC11A2,PPP2R5E,TOR3A,GLRX,CBLL1,UBA3,SRSF7,STAT2,SAV1,TAGLN3,PCDH17,EPCAM,IL22,PRR3,RPL7L1,CSTF3,HENMT1,CSGALNACT2,ST6GAL1,TOMM22,BFAR,TMEM179B,IMP3,UBL3,AFAP1L2,TMEM30A,KCNJ3,COMMD6,B3GALT1,GNPDA1,SFXN2,SNX22,FASTKD5,CST11,NCDN,GNAO1,MRPL34,NDUFB6,TMEM170B,TMEM117,NDUFAF3,CHPF2,IER2,PPP1R1B,RND2,BMPR2,COMMD3,SCG3,OLFM3,RASD1,CCS,NLRP3,ILDR1,SCGB1D1,SHISAL2B,ILF2,ZNF365,BAG3,TOM1L1,KDELR1,KRAS,RPS16,RRM1,RBM22,CNTN2,ASNSD1,NR2F6,HERC4,DKK1,PSMB1,CRIP1,ZMYM3,CCDC86,MTA2,SUFU,MRGPRX3,FBXL19,LAPTM4A,CHCHD4,CHIC2,PGGT1B,SLC38A7,KCNC1,METTL21A,G3BP1,CHAC2,POP5,PSORS1C2,MFSD5,FGFBP1,MRPL18,TMEM101,NUF2,HINT2,SLC16A1,PCDHB13,RPS27A,DAPK3,DSTN,TPD52,RAPGEF5,DBT,ELOVL7,ELMOD2,USP15,LPAR2,FKRP,CNRIP1,APOBEC3G,NTRK2,GNG12,RNF144B,ARG2,DNAJB9,GAMT,ISX,SIAE,GNAZ,RTN4,GLRX5,NRN1,MAPRE1,GNG10,MUL1,SMG9,SEC22C,ZFAND2A,METAP2,MME,TXNDC12,RWDD3,CENPW,ATG4C,SNRNP48,FRRS1,SDHB,GFPT1,NEGR1,FDFT1,SIT1,RPA3,MOXD1,EPHX1,CXCL13,ABHD5,RORB,CKS2,CLDN3,ADAM21,PTEN,RLIM,INO80E,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P2,SERTAD1,ERRFI1,FA2H,HNMT,DPAGT1,CTSA,PPIL3,PHTF2,ZCCHC7,GPR83,LPCAT3,BTBD10,PRDX3,PDCD5,EMILIN1,LRRC14,ZBTB26,CKB,TUBA1B,THAP6,HMGB1,MRPS26,PHF7,GNG11,ZMYM6,EIF2B2,ARF1,RBM41,COPE,SLC25A3,RWDD1,HCFC2,PABPC5,PRKCB,IRF2BPL,LSM5,DCTN3,SUV39H1,RGL1,RPL4,HBP1,CKS1B,DYNLRB2,TP53TG5,DIRAS3,ATG16L1,HDAC11,SIGLEC5,TTLL10,SKP1,CHCHD2,KRT8,PRELP,CSF2,PCYT1B,GCHFR,GJB1,HNRNPH3,LCP1,AGGF1,IZUMO2,ZNF200,TPST1,IFI16,PTPRZ1,SART3,SUPT4H1,FAM174A,MYLIP,VPS39,INA,CFTR,ATG3,CLP1,CLPX,VWF,ATP6V1D,GPR37,ESD,CDKN2D,TMEM39A,ART5,CDK17,PSMB10,FOXC2,CRYZ,CRYBA4,RAB32,PITPNA,BLVRA,APOBEC3B,MLH3,PCBP4,TULP3,HS3ST1,BMPR1B,ADH1B,SRM,MED27,RANBP10,MPP1,BARX2,PSMD1,HSDL2,LYPLAL1,DYNLL1,ABCF1,DUS4L,PLP2,SMG5,RNF139,FMOD,ADRB3,CA12,SLC7A1,TBC1D16,SPATA4,CMTM7,LEMD3,CSRP1,IRF4,CCND3,ARL6,STX5,RAB11B,MARCKSL1,SDR16C5,IFNAR1,SLA2,PYCR1,THOC6,TNPO2,HINT1,RPAP3,RAB9A,RXFP2,CCL11,LCN15,MB21D2,PGAP3,HM13,MCCD1,SLC39A10,VCPIP1,ALCAM,JUNB,CCL24,SNRPD1,LIPA,SMAD9,RELL1,TIMM17A,RNF182,PTPN5,UFSP1,CYP4F22,STK38L,MVD,ARFGAP1,PIGC,SHC3,CDC26,PREP,DDIT3,SLITRK1,SRP72,FIS1,EDEM2,HCFC1R1,CACNB2,RPL28,SEMA7A,NAP1L5,APOC2,CYB5B,MED4,ZCRB1,BCKDK,TRMT5,HPCAL1,LIPT2,MRGPRX1,GPR34,TBC1D1,RPF2,XBP1,TIMM13,ERCC3,GABBR1,PDLIM4,THG1L,ARHGAP19,TACR1,OSBPL8,CEP57L1,CA14,DIS3L,CEACAM5,NAP1L3,EMILIN3,MTA3,DRD3,CHRM5,NACC2,TMEM126A,GPR75,SETD3,GNPAT,FOSL2,ACP2,ACTL6A,STARD7,ZNF436,WBP11,DIO2,EGR1,ZNF343,SYPL1,CHTOP,CORO1C,RACGAP1,RBM3,RRP7A,CCDC126,STT3A,MAGEA4,PIK3CG,RPSA,NPBWR1,UBE2S,HYAL2,ERLIN2,RHOH,ARHGAP15,KLF12,MLN,IAH1,WDR12,RAB1A,GLO1,PDCD1LG2,AMELX,VSTM4,NEU1,PELI1,PIGK,CNOT8,MAP1B,VSTM2L,FBXO31,SCN2B,ANKRD10,TEF,PCP2,TCTA,SOD2,ADD2,DCAF16,SRD5A3,CLRN2,DNM2,REG1A,PLCXD3,C1QL2,MMP20,GTF3C4,SMARCB1,HTR2A,STAP1,ACTR1B,ABCC2,STARD5,FMO1,SUGP1,SDHAF1,ALG5,AQP3,PRELID1,ETFA,CD59,ECD,PSMC5,PRSS1,APEX1,AKT2,GAB1,ITPRIPL2,CHST10,KCNG3,SOX9,COTL1,PNPO,GPM6A,TICAM1,HS3ST3A1,LCN1,RFC4,TLR5,SERPINA3,KCTD20,RASSF4,SKAP2,CLK1,TRAF1,RSL24D1,BRS3,ZMAT3,NAA30,C9orf72,PTGER2,CDR2,NETO1,CGRRF1,DDX39B,HSD17B8,IRF9,LSM4,SEMA3C,DOK6,HERC3,PSMB4,LRRN4CL,SSBP2,PDCD10,GDAP1L1,WTAP,RPL31,ZSWIM7,MGST3,BAD,TSPAN3,HAS3,PRPS1,AKR1E2,CRHR1,NOC4L,UQCRC1,CDKN1B,CMBL,SCHIP1,MEA1,TAF9,PHOSPHO2,SCG5,NMRAL1,MAT2A,TMEM198,TRAPPC2L,RFX5,CD200,TMEM168,TMEM220,ST8SIA4,NCK1,LRP3,STRADB,SIAH1,SLC15A1,KCTD16,PLEKHF1,AHSA1,ZBTB6,GPR78,HNRNPAB,TRIM62,ZNF655,TEX19,RANBP1,RBM5,CTLA4,ATF3,PDLIM3,PRSS37,MAP1LC3B,IFRD1,DEFB1,ACSS2,RHOU,DLG3,RPL22,CEBPE,TMEM176B,RPLP1,SNX11,MT1X,UBE2V1,SERPINB9,TIMMDC1,TRNP1,HELT,IMP4,PDE6A,SEC61G,CENPM,EMX2,HOXB8,SSH3,GFM1,PRM1,GAL3ST4,ADIPOR1,FZD6,MET,SLC7A11,RETSAT,POPDC3,SNRPA1,CTDSPL2,CEP70,ARL6IP5,ANKRD46,ABHD2,TNFAIP8,PSMG2,DTL,NDFIP1,KDM1A,CCDC22,TBCEL,UNC45A,PRSS35,FKBP2,ISG20,RALB,TMEM87A,NUDT1,GMNN,CYP26A1,F2,ARL5B,ESYT1,YKT6,VPS26B,ANKH,AANAT,EDC3,HAPLN2,SAP30BP,WNT2,GMDS,NRGN,CSRNP3,TRAPPC3,LDB1,MFSD3,BIRC5 |
| 3.565e-22 | -49.39 | organonitrogen compound metabolic process | biological process | GO:1901564 | 4594 | 1614 | 18204 | 5365 |
COQ8B,PPP1CB,CELA3B,SOCS3,PRDX4,TAB1,TNKS,NDST3,MTG1,NAA60,ODC1,PIM2,NME4,ST3GAL1,ACOT6,CYP2D6,BRCA1,UBE2I,MRPS23,APOBEC3F,IDE,SLC19A2,RNF113A,DTYMK,MRPS21,TNKS2,PSEN1,MTM1,MRPS28,CASK,TPH2,GSTM3,FITM2,MRPS26,PREPL,ZER1,FBXO11,RPL23A,TYW5,ACTMAP,CDC20,FAF2,DAPK1,MARS1,SLC25A1,HSPB1,SLC35A1,APOBEC3D,OAT,SRM,RPS6KA4,CDK1,ATP6AP2,MED21,CTDSP2,NAA50,GLYAT,UBE2A,PGPEP1,CCT2,ILVBL,FOSL2,SUMO1,COPS5,EEF2KMT,SETD3,IDH1,RNF126,TRIM22,MRPL9,ATP5PF,AIP,CSTA,TST,ATP1A2,ADAMTS20,HSPE1,DCAF11,SAT2,ADAMTS10,MRPL40,NUDT2,CPT2,FBXL4,ADAMTS1,DRG2,SLC5A6,GCLC,PRSS23,EIF2D,PGAM1,GSTM2,DYRK1A,MPDU1,KLK3,MARCHF3,CREBBP,RPL22,ZDHHC24,CUL2,NR4A2,EPO,IKBKB,CHCHD4,MKKS,RPS20,EIF4H,NCSTN,EZH2,UFD1,HECTD1,UBR7,SPCS2,GSTO2,SDHC,COP1,PRKCQ,GOLGA7B,ST8SIA4,DESI1,B4GALT6,JOSD1,CHST10,ABCC5,SVBP,LCMT1,CTSC,FKBP8,COX10,PGAP4,UBE2D3,PSENEN,COMT,TBCE,CHMP1B,ENO2,DNAJC2,DDIT3,GSTT2B,EEF1B2,UBE2E3,PGGT1B,DCUN1D1,ELOVL6,HSP90B1,APOBEC3B,RABGGTB,USP16,NFE2L1,GUCY1B1,NUDT3,STRADB,LMAN1,PRKCA,GANC,MTHFS,RNF144B,WDR83OS,EIF4E2,AZIN2,RAD23B,ACVR1,PPIH,POMT2,AMT,EDEM2,F2,PLSCR1,CAPN1,MAP3K11,DDRGK1,NAA15,ZC3H15,MMP21,RAF1,GID4,TRAF1,DBH,PRKX,MBL2,ABHD17A,ZDHHC8,DFFA,KCTD11,FEM1A,KLK6,VPS28,H2BC1,RAB6A,GTPBP1,CARS1,PC,HSPA13,RPS23,IFI27,ADCY3,NEURL2,DCAKD,ELOVL7,PMAIP1,BAP1,CD36,HYPK,RPLP1,IREB2,NDUFS3,PCK2,SMURF1,MAEA,PRPSAP1,RHOBTB3,GUK1,UBE2B,JAK1,HACD3,OGDHL,CPNE1,KLHL24,ANAPC2,EEF1G,RPS2,NIM1K,FGR,RPS17,RNASEL,BRAP,NANP,PI3,KBTBD13,STAMBP,NDUFB6,ERP29,CSK,CRMP1,TRIM34,HAS3,ENO1,LDLR,AURKAIP1,GAL3ST4,NEUROD2,EEF1A1,ST13,PPARA,PELI1,PAK5,UCK2,RPL39,TRAF7,FBXL19,MED31,JAK2,PTEN,GALNT17,CAND1,USP3,GSTM5,UGCG,ACACA,ABCE1,RIOK2,EIF2AK2,MRPS18B,SEC61B,UBE2M,NUP153,STK26,PSMC3,ATP5IF1,UBE2N,DESI2,CERS6,SNX5,RPSA,TTL,PRKD3,PSMD12,NAA16,EIF3D,KARS1,ARMC8,SLC1A1,CTNNB1,HYAL2,GPT,KLK5,COPS7B,NTAQ1,CYFIP2,UBE2V1,UBE2G2,PYCR2,DCAF16,RNF128,PDIA2,MAPK4,RPS27A,ASB3,PRMT6,PTS,NFE2L2,DNAJB4,GCNT3,HNMT,FBXO7,GOLGA7,BMPR1A,HACD1,SLC38A1,TMEM199,PDIA6,RTL4,SMUG1,UBASH3B,SPSB3,TRIM3,GSTO1,MGAT1,EIF3K,EIF1AD,EIF2B5,RNF146,SERINC3,MED17,GALNT1,TESK2,TRIM45,STK16,METTL22,SENP5,MMP28,NME1,SLC25A21,DAG1,SERPINH1,EIF1B,CBLL1,MRPL51,SNRPB,RAB40AL,LEP,SQSTM1,GSTT1,BMPR1B,RPL32,DISC1,SLC11A2,PML,NUDT9,RPL24,FUT9,EIF2S1,NDUFB5,HS3ST1,SPATA2,UBXN2B,MRPL33,MRPL20,CD38,CD2AP,FMO3,NEK2,MRPL24,TPST1,ZDHHC16,FAM20B,DNAJC7,UBLCP1,NAA11,CSGALNACT2,FKTN,DNLZ,NDP,MMAA,UMPS,ATG4A,NT5C2,PCBD1,SARM1,EIF1AX,ELOC,CLU,CISH,RPL19,RPL3,MED30,SDS,ANAPC13,OTULIN,RPS7,GRPEL1,STK38,PSMA1,EEF1E1,ALG5,AK2,FURIN,RPL18,RPS9,BLVRA,MRPS16,ANAPC15,FBXO25,STAMBPL1,GSTA4,KLHL3,HTRA2,HSPA5,SOCS5,SPOP,TRIM54,RPL10L,SLC6A8,MRPL57,IGFBP3,CYP4F22,NUDT1,ZDHHC15,SPR,TUSC3,EPHA4,MMUT,CSNK1E,FBXO32,IFT172,RCHY1,SAT1,IGF1R,GGH,ABHD10,PPIA,AUH,PGAP3,ATP5F1A,SLC6A7,PMM2,HERC3,ETFBKMT,NDUFB7,RIMKLA,ZBED1,TLR7,OS9,GAD2,KDM1A,STPG4,CCS,HGS,SLC19A3,PRMT2,PPP1CC,MAP2K1,CTU1,HCST,IL1R2,RPL7,OLR1,PDF,ALG11,MRPS17,GXYLT1,BECN1,TOPORS,TNNI3K,PSMB1,DNAJB9,DLG1,CHST11,UBXN10,UCHL3,TPSG1,RPIA,PDE1A,RLIM,NEDD8,GTF2B,OSBP,ATP5MG,RNF11,EIF2B3,RPL29,TRIM8,PGAP2,MSL2,COL3A1,GDPD3,SDF2L1,SEPHS1,FAM20C,PLA2G15,FEM1B,GALNT4,ISG15,SULT1A3,RNF167,MARCHF9,RNF139,HINT1,HMCES,RBCK1,TRIM44,PTPN4,SIAH1,RPS26,GPHN,PSMB9,B2M,ATAT1,EIF2B2,KLHL22,BPNT2,ALG2,PPWD1,NQO1,CDO1,PPP2R1A,GSTA1,PCMTD2,CHMP5,MRPL10,RPL15,PAPSS2,F10,GMPPB,SGTA,APOBEC3H,PIGC,CDC26,ACCS,CIAO1,GNAI3,STK4,VCPIP1,ST6GAL1,TNFAIP6,FBXL14,NDUFV2,MAP3K3,SOD2,NEK7,PTAR1,FTSJ1,OAZ1,CSGALNACT1,ANAPC16,CHORDC1,TRIP4,UGT1A1,GHR,LARGE1,B3GALT1,SPTSSB,TOR1B,TSSK1B,TMEM165,HMOX2,RPS15,TLR4,MPP1,FOLR1,CDK9,DCTD,TYMS,RNF141,ELOVL1,CHST2,GALNT12,CNDP2,SDHB,CTSD,OTUD6A,MAPKAPK3,GRPEL2,SHMT1,GALC,TMUB1,DIO1,CDK8,PSMA2,PDIA3,ORMDL3,DDAH1,PFDN5,SH3BGRL,BCKDK,NSFL1C,MED11,EPHB6,ATP5MK,MRPL34,OAZ2,ITGB8,PLG,PSMD3,CSKMT,ADSS2,PSMB6,EDNRA,NMI,RPL27A,VPS18,NUDT19,DUSP21,ASRGL1,TAPBP,PIGW,MED27,ORMDL1,ADM2,PPP2R5A,PSMB11,MGST2,RPL10,METTL18,SRD5A3,DNAJB2,LPCAT3,B3GALT4,ST3GAL2,DNAJC3,RAB23,DCAF4,ACVR1C,ACSL4,CHAC2,SUCLG2,ERLIN2,ZDHHC14,BAX,HEXA,TRAF3IP2,USP38,GP9,ENPP4,TOM1L1,LAMP2,PAIP1,MMP9,DEGS1,PSMB7,SEPHS2,RPLP2,HECTD3,AKT2,HS3ST5,PSMA6,COPS2,DLAT,UHMK1,FUT1,DHPS,OXSR1,DAPK3,E4F1,TSG101,PPP5C,NR1H2,PLA2G5,MATCAP1,SYVN1,SPRR1B,CDK5RAP3,DOHH,SCPEP1,ACER3,FN3KRP,EGLN2,TSPAN5,TOLLIP,EIF4A2,CPE,COQ8A,SLCO2B1,KIT,TGFBR2,TP53I3,UBE2D1,RPE,APH1A,IGF1,SGMS1,MRPL23,UCP2,UBE2W,CHCHD1,TTR,PSMA5,SKIC8,CALR,NSG1,NUDCD3,TNFAIP3,GID8,GSTP1,ATP5PD,KBTBD2,PPP3CA,HERC4,DYRK1B,AKT1,IL1B,PCCB,UBA52,DNAJC24,PFKFB2,EIF4B,ADAM21,HSPB6,RPS12,NDUFB4,IL15,PPM1G,MRPL41,RCE1,FABP5,GTPBP2,RPL31,HMGCS1,RNF115,CMPK1,PRRT1,CCAR1,TRIM10,RAN,ZNRF1,CCDC47,CDK17,SETD4,CUL3,PSMD1,NDUFS6,PGA4,ASB8,SLC52A3,TCP1,AK5,PIGY,CRYM,MRPL49,PAFAH1B1,SPOPL,NDUFS2,ADK,GMPS,CDC23,CACUL1,LYPLA2,OARD1,SERINC1,CAMP,ADRM1,DBT,CHST1,NDUFB10,NT5C3A,TRIM35,G2E3,TOR2A,ABCG2,COX11,ANKIB1,MGAT5B,MAPKAPK5,UCK1,HPGDS,ATP5F1D,DCUN1D3,EXTL2,DRD1,PIGA,CHRM3,CACNB4,MRPL12,SGMS2,MRPS9,PPM1M,DUSP9,MRPL13,RPS13,ENTPD4,TLR2,FKBP4,DPEP3,ST8SIA5,PTHLH,YIPF5,CSNK1A1L,RNF10,PICK1,BPGM,RNF26,PPIF,STAT5A,ERH,KCTD10,UCKL1,PARP2,WEE2,PRSS8,MRPS18C,GLUL,RLIG1,ASB1,PRKAB1,EGLN3,LACRT,BIRC2,DUSP1,YES1,PSMC1,BFAR,PPME1,DERL2,ACVR1B,MED10,SCG5,ARFGEF1,NME2,HDAC6,MRPL17,DPM2,ALKBH4,TMCC2,STK11,LAP3,ACHE,TRIM11,PFDN6,ATP6V1A,HTR1A,MRPS33,DCTPP1,RC3H2,SELENOO,VCPKMT,CRAT,USP8,FKBP1B,CMAS,ERLIN1,LDHB,PTPRZ1,CBFB,HSP90AB1,MSRB1,KCTD17,SMPD2,LYPLAL1,IFIH1,NUDT5,ZMPSTE24,WWP1,COPS4,ABHD12,TRIM26,PLPP6,RPS27L,ARL6IP5,EGR2,DNAJC19,FMO2,KLHL7,DNAJC30,SPON1,PMPCA,GLO1,NUDT18,MRPL16,WWP2,SNCB,SELENOF,CREB1,ANAPC4,IER3,HSPB2,APOBEC3G,PRDX3,OST4,HTR2A,MARCHF5,PELI3,EIF2S2,NDUFA12,SOCS4,HSP90AA1,USP15,WDR45,CDK5R1,DAD1,PFDN2,USP14,EDEM1,AHSA1,PRKCB,CTBP1,PRCP,TECR,BAZ1B,ATP1B1,P4HA2,CDK7,NDUFA2,MRPL36,CISD1,SRPK2,SNRPD3,KLHL12,RNF39,SLC6A3,FCN2,TGFB2,QPCTL,METAP1,PAK6,RING1,ATP5F1B,CPT1B,USP13,TRIM37,NDUFA1,GAL3ST1,PDE8A,PTPN22,PXYLP1,EIF3J,FMO1,ABHD14B,QNG1,TTC4,PDHB,VPS4B,FARSA,UBE2F,CLN8,UBE2H,GNPDA2,MYRF,GAPDH,EDEM3,RPS5,FBXO22,PYCR1,CEP41,AASDHPPT,ATP5F1E,AK3,ITK,MRPL47,PLAAT5,PCYOX1L,OSBPL8,TSPO,GNPDA1,KDSR,RNF20,STK24,PDE9A,RNF187,LIPA,NUDT7,CSNK1A1,CCNA2,RPL23,GNPTG,PFDN1,IDO1,SPPL3,EEF1AKMT3,ZNF451,IL21,FHIT,VPS4A,VASH1,FGFR1,MTHFD2L,PTPRQ,NDUFAB1,TTLL10,ACSS2,GGTA1,CCL11,ENC1,PTPN11,HUWE1,UGDH,FBXL7,CDK6,MRPS18A,FKBP10,TRIM27,CTRB2,SEC11A,SPHK2,ATG3,SPCS1,RAG1,FBXW11,QRSL1,OGG1,TRIM23,MTRES1,DDR1,STK38L,RPS16,AIPL1,BOLA2B,UFM1,RPS28,PSMD14,FBXO3,ACOT8,GALNT2,PLAAT3,APPBP2,ROCK2,TRAF2,FBXO31,ETF1,TRIM6,TMEM106B,SENP8,EEF2,RPS3,PSMD4,RPS29,HMBS,MME,KLK9,EPHA2,MINDY3,STX1A,CAB39,RNF182,MAPK10,DPAGT1,CHMP2A,EIF4E3,SLC25A42,SNAPIN,RPL26L1,RPLP0,GANAB,RMND1,ABCC2,RWDD1,MFN1,DPH5,ENPEP,MRPL22,ECRG4,INHA,STOML2,ASMT,UBE2E2,DUOXA2,UBE3A,RNF14,DPP10,COPS7A,USP2,UBB,RNF122,PNP,OVGP1,MRPS7,HSPD1,WSB1,SULT1B1,ADGB,MRPL11,GNMT,UPRT,SLC1A3,CHPF,CDKL2,TSPAN15,PSMD7,AKR1A1,SPTSSA,GSK3A,EIF3G,ADCY2,DERL1,BAD,B4GALT7,HTRA1,MMACHC,PSMB3,CDK12,GAMT,CTDSP1,PLAA,SKP1,MARCHF4,RIC3,TRIM24,WDSUB1,ATG4C,EP300,RNF103,UQCC3,WDR77,RPN1,NPC1L1,HSD17B10,CRTAP,INMT,CTSK,SLC1A2,NPR2,TMEM106A,RNF208,GPX1,DPH3,UBE2V2,CDC7,MRPS35,PRMT5,MRPS34,DDI1,SELENOS,SDHAF2,UBXN6,DRD3,UBL5,MECP2,B4GALT4,BMPR2,BNIP3L,MRPL50,LYPLA1,SLC30A5,SLC25A32,STYK1,DNAJC5,TMEM208,MAN1A2,PIGK,C1GALT1C1,FAH,RPS24,IFI16,TLCD3B,PGK1,CCT5,DDAH2,ASNSD1,NTRK2,GSTK1,HS3ST3A1,NBN,FBXO44,MACROD1,BIRC5,PGRMC1,GPR37,NUDT4,DTL,RPL8,FAU,RNF121,PGM1,MRPL53,OAZ3,DLST,USP30,XPNPEP1,EXT1,PTGES3,GXYLT2,MTMR2,SRGN,SRC,PPIL3,CDK20,MSRB3,PSMB4,ANGPT1,SUMO2,PPID,ISCA2,PSEN2,CHDH,CHPF2,ATP5MC3,MGAT4B,ATF4,TRIM21,IDH2,IRF2BPL,FBXW4,CLPX,PRSS37,CHI3L1,PRSS12,CYP2C9,SLC25A44,MRPL18,ARG2,B3GNT2,THTPA,LIPT2,P3H1,MGAT4A,THBD,NUDT12,TTC1,GSTM4,NLGN2,TRAF6,CHKB,CCNF,NAE1,URAD,ACAT1,TRIB1,RNF40,TMEM59,ATG16L1,SLC7A11,GPAA1,DUSP22,TRIM62,IRF2BP1,SELENOK,ZDHHC4,PPAT,UBL4A,DNAJC4,NDUFA5,FNTB,TYW3,MOXD1,CYP3A43,F9,RPL17,CSNK1G3,RNF7,CMA1,YAE1,USP5,RUVBL2,GSTA2,NEU1,CDC37L1,NTMT1,PSMB10,NDUFC2,IL4,FXN,ATP5PO,PDP2,FAM98A,RPL37A,DYRK2,HACD2,CDC16,TLR3,TRIM68,RPS14,PPP2R5E,MTMR6,ALDH1L1,FZR1,SOCS2,CRYAB,SECISBP2L,NDUFS8,SHPRH,REN,PCSK2,EIF5A2,PDE7A,ACADSB,UST,MAP3K12,GDE1,SETD7,SLC48A1,RNF34,FBXO8,STK3,XXYLT1,EIF4EBP2,FKBP1A,CTTNBP2NL,OTULINL,ING5,PELO,PRPF19,DNPH1,ANAPC11,CTSB,PPTC7,HSPA14,DRG1,SNRK,VIPAS39,AZIN1,DHRS7B,PTPN5,CSNK2A1,CPEB1,ERO1A,PPIG,BAG3,CBL,NDFIP1,PCMTD1,MTRF1,CYP1A1,MVD,DNAJC25,DCAF5,DPEP1,TMUB2,GFM1,CHST9,ZFAND2A,DUSP3,ST6GALNAC3,KLHL15,PAOX,AANAT,GZMK,LTO1,LORICRIN,OTUD7B,LDHA,FKBP2,GLRX2,OLA1,FAM8A1,RNF8,PRSS1,CFAP20,HAND2,CDC123,DET1,METAP2,TRIM15,FAF1,FAR2,HEXB,TRIM52,B4GALT3,NAA35,ASB7,SLC25A12,CAMKV,UFL1,CHMP4C,LYG2,PPP2R3A,AGA,MDM2,SUMO3,PSMB5,SPCS3,NCBP2,SLC25A39,RPL35,RPL9,BAG2,PTPN1,HSPA8,PPIB,ST3GAL4,CLCA1,FBXO30,CRBN,MRPS11,RARS1,TOP1,MPST,LCN1,RNF152,ILK,CASP4,RPL6,SLC22A12,GGT7,TNFAIP1,PPM1D,RP2,PDHA1,NLRP3,KCTD9,BOLA3,FUT8,ABCF1,CSNK2B,CHST7,GGCX,RNF133,DUSP18,PPT1,MUL1,ERLEC1,CYP3A5,DNAJC10,STUB1,RSL24D1,KLHL9,CDK5,CERK,RPL28,KDM2A,RNF5,HECW1,CCT8,DUSP10,GFPT1,URM1,PAX6,UQCRC2,RPL7A,PNPLA8,OTUD6B,CHMP2B,NUS1,SLC35C1,TP53INP2,CASP12,PRKAG1,TUFM,ATG7,UBA3,HDAC3,ZBTB16,TKTL1,MTAP,RIMKLB,PREP,HM13,DNAJB6,MDH1,AQP11,PSMB2,UBE2S,B3GALNT1,TNIK,JKAMP,MMP20,MAGEC2,IMMP2L,UBE2K,ABHD4,MMP14,EIF4E,NDST1,CHMP1A,PPP2CB,PPP1R12A,AKT3,RPL12,CLIP3,RNF181,GPD2,KLHL25,CKB,PPP3R2,RPL4,USP46,B4GALT1,PCSK9,B3GALT2,ATP5MC1,GLCE,PSMA3,PRKCE,RGMA,DCK,PARL,DIO2,XBP1,PNPO,RPL13A,RPL27,PFDN4,DOLK,SLCO1B3,SPSB1,PAIP2,TRIM63,PAK2,CYTL1,MRPL52,SOD1,CLK4,FEM1C,PPP1R11,DIO3,FBXO9,SIRT7,ASPA,PSMD6,PSMA4,BAK1,B4GAT1,PRPS1,BMP1,SIAH2,RPS4X,HACD4,DUSP26,CCT7,PDRG1,RPL26,FKRP,GPC1,NSMCE3,PDE1B,UNC45A,RPS11,EIF3E,NUDT16,MTPN,ALPL,RRM1,PPM1B,VRK1,CTSA,CLK1,PPM1K,SAMHD1,METTL21A,CDCA3,ST3GAL5,VKORC1L1,AGK,KLF1,YWHAZ,RNF148,PRKACB,HS2ST1,ELOVL4,CAPN2,AREL1,NDUFB8,STT3A,PTDSS1,CAMK1,FBXL3,NMRK1,ELOVL3,F7,ATP5PB,CHST13,DPH6,ZC4H2,MAP3K21,RHBDL3,ROCK1,GFM2,CDSN,ZFAND2B,RPS10,ASB11,MMADHC,ADPRH,UTP25,RPL35A,BACE1,PDE4B,PARP11,RNF41,RPL10A,NPPC,CCL2,GLRX5,PSMC5,DUSP6,DNAJC1,EIF5B,RMND5B,PDE2A,SLC16A10,APOBEC3A,DMPK,MYLIP,MRPS25,G6PD,TBCEL,USE1,DPP4,VPS54,PIAS1,TBK1,CDK4,DCUN1D5,VSIR,APEH,UBAP1,CERS2,UBE2L3,GPAM,TRMT112,TRIM32,ABHD16B,KBTBD6,PSMC4,FA2H,SYK,NLRP1,PCYT1B,FBXW7,ZDHHC17,S100A8,TESC,PPIC,APOBEC3C,SELENOT,TRIM5 |
| 3.944e-22 | -49.28 | post-transcriptional regulation of gene expression | biological process | GO:0010608 | 1072 | 460 | 18204 | 5365 |
MIR149,MIR324,MIR146A,RPS27L,MIR208A,MIR342,MYD88,MIR504,ALKBH5,MIR662,MIR31,RPS9,MIR452,CD28,MIR150,ZCCHC17,MIR876,FASTKD5,MIR101-2,CAV1,MIR661,MIR760,MTG1,RC3H2,MIR557,MIR1225,MIR105-2,MIR190B,MIR132,EIF5A2,MOV10,MIR194-1,MIR761,MIR184,MIR484,MIR126,MIR302B,MIR553,DAPK1,MIR556,SECISBP2L,TDRD7,HSPB1,AGO1,MIR490,MIR142,MIR106B,CCL5,RPS14,MIR605,MIR200A,EPHA4,MIR3173,MIR942,MIR216B,MIR7-2,MIR489,DICER1,PYM1,CNOT6,MIR215,MIR656,MIR20A,MIR551B,CPEB1,CSNK2A1,HNRNPA0,CIRBP,MIR429,ZC3H14,MIR936,MIR511,MIR488,HNRNPC,MIR558,MIR200C,MIR425,MIR29C,TSN,EIF4EBP2,MIR1260B,MIR339,XPO5,PELO,MIR708,PIWIL2,MIR152,MIR1226,MIR147B,MIR940,MIR517B,MIR30D,MIR600,DHX9,MIR367,MIR25,MIR612,NCK1,MIR9-1,MIR346,MIR449B,MIR370,METAP1,MIR144,MIR192,MIR597,MIR503,MIR212,RBM3,MIR626,MIR30A,BTG2,MIR193A,IMPACT,DCP2,MIR711,MIR193B,SESN2,MIR106A,MIR218-2,MIR195,YTHDF2,PIWIL1,IFRD2,EIF4H,MIRLET7G,EIF2B2,MIR198,MIR554,MIR1249,UPF3B,MIR28,MIR335,RNF139,MIR638,GAPDH,MIR422A,MIR934,CNOT7,ENC1,MIR147A,MIR590,MIR586,MIR340,CNOT8,MIR99B,MIR26B,PIWIL4,MIR155HG,MIR770,MIR216A,MIR1-1,MIR34A,NCBP2,MIR609,ZC3H7A,MIR133B,MIR671,MIR188,TENT5D,MIR583,CASC3,MIRLET7C,MIR657,MIR552,MIR581,MIR1277,PRKCA,MIR502,MIR17,MIR214,EIF4E2,PAIP2B,MIR764,MIR338,TYMS,MIR424,DAP,MIR301A,TENT5C,LSM14A,MIR105-1,USP16,MIR16-2,MIR875,LARP4B,MIR98,MIR1296,MIR649,MIR361,MIR23A,MIR628,MIR495,YTHDF1,SH3BGRL,MIR615,RGS2,MIR624,TRAF2,MIR191,MIR145,ETF1,PDE12,EEF2,RPS3,MIR636,TNF,POLDIP3,SHMT1,MIR9-2,MIR505,MIR1298,NGRN,MIR611,MIR567,MIR640,ROCK2,MIR375,ELP6,MTG2,MIR96,MIR21,MIR30B,MIR519D,MIR648,DNAJC3,MIR651,TNFRSF1B,MIR330,MIR548C,MIR196B,MIRLET7D,MIR148A,SYNCRIP,NGDN,MIR383,TIA1,METTL18,MIR580,RPL10,MIR210,UCN,MIR129-1,MIR593,MIR887,MIR33B,RMND1,IREB2,MIR454,DXO,MIR197,EIF4E3,MIR577,MIR204,MIR423,MIR10A,MIR130B,CARHSP1,MIR449A,MIR589,TENT4A,MIR607,KLHL25,DAPK3,MIR186,AKT2,UHMK1,MATR3,MIR1224,MIR885,TRAF3IP2,MIR379,EIF4E,MIR1-2,IL6,MIR633,MIR107,PAIP1,THRAP3,MIR190A,MIR223,MIR185,PCBP4,RNASEL,DDX1,PAIP2,MIR221,MIR155,MIR130A,MIRLET7B,MIR497,MIR492,RPL13A,MIR377,MIR320A,MIR631,EIF4A2,MIR1251,EIF2AK2,MIR206,MIR643,MIR450B,MIR448,MIR10B,DIO2,ABCE1,MIR500A,MIR573,MIR125A,MIR187,TIRAP,ACO1,MIR99A,RPS4X,EXOSC8,MIR92B,RPL26,MIR595,MIR9-3,ITGA2,MIR211,EIF4B,MIR374A,ELAVL4,MIR1271,MIR182,MIR578,CLP1,AKT1,MIR569,MIR938,MIR136,MIR1227,LSM14B,INPP5E,TSNAX,MIR345,MIR877,MIR604,MIR384,DKC1,CNOT2,MAGOH,EIF3D,MIR331,MIR675,CALR,MIR639,MIR218-1,MIR296,MIR563,MIR618,MIR551A,EIF3K,EIF4EBP3,MIR153-1,EIF2B5,MIR493,METTL14,MIR625,MIR944,RAN,MIR24-2,MIR100,MIR301B,MIR922,TRIM3,MIR30E,MIR549A,MIR652,MIR29A,EXOSC3,MIR874,MIR542,MPV17L2,MIR137,MIR769,MIR455,MIR181C,MIR298,MTPN,EIF3E,MIR194-2,MIRLET7I,MIR532,MIR148B,TCOF1,MIR601,MIR140,ATF4,MIR939,POLR2G,MIR765,MIR891B,MIR572,NRDE2,MIR34C,EIF1B,UQCC2,PIWIL3,BZW2,MIR139,ROCK1,STAU1,MIR135B,MIR143,PHAX,MIR15A,MIR34B,MIR873,APEX1,MIR7-3,MIR378A,VIP,MIR32,MIR632,MIR1180,MIR181D,GTDC1,MIR802,MRPL13,MIR183,FXR2,MIR373,MIR222,CYP1B1,TACO1,EIF2S1,MIR141,MIR16-1,MIR491,PABPC1,MIR937,IGF2BP1,MIR7-1,MAPKAPK5,EIF5B,DNAJC1,MIR616,MIR208B,ELP3,MIR653,MALSU1,MIR592,SELENOT,MIR129-2,MIR23B,MIR205,MIR924,MIR599,BOLL,HNRNPD,TNRC6C,EIF4A3,MIR920,ELOC,CNOT6L,MIR363,MIR101-1,MIR24-1 |
| 4.474e-22 | -49.16 | N (nucleocapsid phosphoprotein) | protein interactions | 43740575 | 1174 | 478 | 19454 | 5460 |
EIF2S2,LIG3,ZNF330,RPS3,SRPK2,PPAT,RPS17,CEP85,SUB1,MORF4L1,RPF2,MAT2A,ELAVL2,DNAJC10,EIF3G,TWNK,HNRNPH2,BANF1,HSPA5,ZC3H15,H2AC13,NTPCR,GTF3C4,SETD3,CAPN1,UTP15,ZNF326,H2BC11,SDCBP,RPA2,AIP,SDHB,SYNCRIP,EEF1B2,SURF6,DKC1,ILVBL,RPS16,DNAJC1,MZT2B,TMA16,CMSS1,KARS1,RPL10A,RPS2,SNRNP70,RPL3,SLC25A11,SNIP1,CAPZA1,IMP4,KPNA2,H2AX,RPAP2,SESN2,NECAP1,ARPC3,TFCP2,EFHD2,ZNHIT6,IREB2,SNRNP40,CAVIN2,CHTOP,H1-10,RBM27,FTSJ3,GCC1,HSPA8,XRCC5,SNRPA,PYM1,STAU1,HNRNPA0,EMC1,EHHADH,RPL27A,NCOA5,KLC2,S100A8,SRSF1,PGS1,LYAR,TCP1,FAM98A,EIF2S1,UTP6,PPIB,MRPL9,DRG1,PDIA6,RTCB,RBM3,CCT8,TOP2B,PABPC1,POLDIP3,HNRNPDL,RPL28,NUP42,MAPK1IP1L,TOP3B,RPL18,CRKL,MTA2,CFAP298,RPS20,RTRAF,PRKRA,EIF4A3,SMAP2,RPL22,SEC63,SNX3,RPL13A,TXN,MAGOHB,NONO,TUFM,ATP5F1A,NTAQ1,CASC3,IVNS1ABP,CHORDC1,ARPC2,SQSTM1,H2BC12,MAVS,MTDH,PRPF4,TNFAIP8L3,AATF,CRYZ,NHP2,NUCKS1,HMGB1,RPL4,EIF5B,NPM3,GTF2I,COMMD3,MYL12B,RPS14,MACROH2A2,RPLP0,LSM2,HSP90B1,LMNA,JUP,CDK1,PWP2,H2AZ1,HACD3,AIFM1,NOP9,DBT,TOP1,GLO1,MPHOSPH10,SLC2A1,HSD17B10,HINT1,PRDX4,MRPL22,RPS13,THRAP3,WASL,BACH1,PAK1IP1,RPL15,NECAP2,MAP1LC3B,LBR,EEF1A1,YTHDF2,MRPL11,CCDC47,RAD23B,SRP72,ILF2,RPL37A,AP2M1,UBE2S,RAN,FAU,GNB1,SNRPB2,RPL19,RPL7L1,RPL35,AK3,SAMHD1,NOP16,PYCARD,LMNB1,CCDC86,DCTN3,HADHA,TTC1,CRY1,UPF3B,G3BP2,NSFL1C,IL1B,RAB6A,PPP1CB,PRKAB1,H1-5,MYL6,APOBEC3C,PPARG,RPLP1,HP1BP3,XPO5,PHB1,SP2,SNX2,RPL7,NOP58,EIF3D,TRA2A,STOML2,CLPX,PSMD3,PRPF19,PRDX1,PPP3CA,RPL23,LYZ,RSBN1L,HBA1,CSTA,SRSF8,RPS24,PPAN,SRSF4,ADO,G3BP1,LASP1,MAK16,MACROH2A1,SRP54,SEC61A1,CSNK2B,PSPC1,CDC20,GRPEL2,EIF4H,ST13,CFL1,RPL7A,SMARCA5,SLC25A1,CDKN2AIP,IGF2BP1,MECP2,LSM12,RPL27,SEPTIN6,STK38,RPS15,WDR3,AGO1,LUC7L3,CYC1,TFB1M,HBB,ALYREF,RPL32,SSBP1,GAPDH,API5,PPIL4,MZB1,MAP4,LSM3,AKAP8L,RPL24,H2AC4,DHX9,RPL17,HNRNPK,H3C1,TP53,IMP3,STRBP,SMU1,PRMT5,DDIT4,RPL10,STAT1,STAT2,MATR3,SNRPB,BTF3,HNRNPC,LDHB,HNRNPAB,CREBBP,RCL1,CRMP1,RPS26,H2AZ2,CIRBP,CKB,DDX5,SF3B1,DDX39B,EEF1G,FXR2,TRA2B,EFHD1,CNDP2,CSNK1A1,NUFIP2,EIF4B,FUBP3,RAB35,CCT7,HSP90AB1,SNRPD3,SNRPA1,SUMO3,DBR1,RPS10,ECHDC1,HNRNPL,YWHAG,XPO1,YWHAH,RPL6,DDX50,CNOT2,BAZ1B,UBFD1,DDX1,CBL,DRG2,NCK1,TRIM21,EWSR1,MYO1B,ABCF1,LSM14A,RPL31,PRPS1,TFG,RPS4X,RUVBL1,HNRNPF,RPS7,EEF2,H1-3,RPS23,TUBB4B,PLS3,RPS12,ALB,CTTN,TUBA1B,ENO1,EIF2AK2,DEK,PDCD5,FERMT2,MGST3,FBXO7,RPL26,DHPS,STK38L,MAPRE1,CDC73,ANAPC16,SOD1,BRIX1,UTP23,CHMP2B,MRPL17,CCNA2,UBA52,SF3A1,HAUS2,TP53INP2,SH3GLB2,STAMBP,HNRNPH3,RPL26L1,RARS1,COX6C,TES,NAA30,KRR1,EIF4E2,RLIG1,SMAD3,RPL12,RPL35A,SPATS2L,H2AC14,GRSF1,MOV10,SMG9,NME2,RPL23A,SFXN1,NKRF,RIGI,SMN1,NSMCE3,TRIM62,CCT5,NDUFS3,LLPH,RPS9,SNRPD1,SNRPD2,ERH,PRRC2A,TAB1,ACTB,RPF1,TUBB,PDLIM3,STARD7,PRPF31,NLRP3,LSM14B,RPS5,SCFD1,HSP90AA1,PFDN2,YWHAZ,ZCRB1,EMG1,YTHDF1,NOP53,SRM,UCHL3,PGRMC1,ARCN1,SLC25A3,MFAP1,LARP4B,FEM1A,USP39,RPLP2,MRTO4,RPL9,RPL8,DHX15,PPIA,SRSF10,HNRNPA1,IFIH1,PDAP1,SLC20A1,HNRNPD,PPM1B,WDR12,SKIC8,SRSF7,BAG2,HNRNPA2B1,SLC25A5,PREPL,NUDT5,HSPD1,SSRP1,RPS27A,RPL29,ACTN4,FAF2,CSNK1E,DPH5,CKS1B,SNRPE,RPS11,RPN1 |
| 6.609e-22 | -48.77 | translation regulator activity | molecular function | GO:0045182 | 428 | 222 | 18094 | 5411 |
MIR339,MIR223,MIR125A,MIR30A,ABCF1,EIF4EBP2,MIR105-1,MIR573,MIR148B,MIR214,MIR1260B,IFRD2,MTRF1,MIR551A,MIR34A,MIR10A,MIR505,EIF4A2,FXR2,MIR330,EIF2B5,MIR100,MIR198,SHMT1,MIR424,GTPBP2,MIR345,EEF2,MIR548C,MIR298,MIR98,EIF5B,MIR30E,MIR1298,MIR17,MIR140,MIR99A,MIR31,MIR136,BOLL,MIR454,MIR346,CIRBP,TRIM3,MIR885,EEF1B2,MIR1277,MIR96,EIF2B3,MIR30D,MIR185,MIR145,MIR181C,MIR497,EIF4E,MIR34B,MIR491,MIR661,RPL10,EIF3D,GFM2,MIR183,MIR147A,MIR10B,EIF3K,EIF3J,MIR340,MIR222,MIR335,MIR511,MIR208B,MIR572,MIR552,EIF1B,EIF4E2,MIR302B,MIR490,MIR874,MIR23A,EIF3E,MIR1-1,MIR148A,MIR9-1,MIR101-1,MIR191,PABPC1,ETF1,MIR208A,EIF4H,PAIP2B,MIR590,MIR141,MIR363,MIR137,MIR296,MIR455,MIR149,MIR493,COPS5,EIF1AX,MIR320A,MIR21,MIR429,EIF5A2,MIR142,MIR182,MIR146A,MIR492,MIRLET7C,MIR106A,MIRLET7B,MIR301A,MIR143,MIR342,TUFM,EIF2S2,MIR210,MIR425,RPS27L,MIR29A,RPS14,MIR150,MIR218-1,MIR939,RPS9,CPEB1,MIR24-1,EEF1G,MIR193A,MIR188,MIR877,MIR383,MIR215,MIR378A,MIR126,MIR155,MIR33B,MIR26B,MIR373,IGF2BP1,MIR338,MIR187,PAIP2,MIR30B,MIR301B,MIR144,EIF4EBP3,MIR876,EIF3G,MIR204,MIR181D,GTPBP1,MIR657,MIR625,TYMS,MIR374A,EIF2S1,MIR195,MIR130A,MIR448,EIF4E3,MIR769,PAIP1,MIR20A,MIR28,EIF2D,MIR194-1,EEF1A1,MIR640,MIR423,MIR139,MIR192,MIR211,MIR708,EIF4B,MIRLET7G,MIR639,MIR152,MIR129-1,MIR361,MIR221,MIR106B,MIR25,MIR132,MIR34C,MIR186,MIR190B,MIR92B,MIR133B,MIR212,MIR384,MIR206,MIR15A,MIR638,MIR153-1,EIF1AD,MIR379,MIR503,MIR675,MIR193B,MIR130B,MIR29C,MIR200C,MIR107,MIR135B,MIR1224,EIF2B2,MIR1271,MIR873,MIR205,MIR920,GFM1,MIR519D,MIR3173,MIR488,MIR32,MIR16-1,MIR99B,MIRLET7I,MIR449A,MIR495,MIR200A |
| 9.119e-22 | -48.45 | SNAI1 (snail family transcriptional repressor 1) | protein interactions | 6615 | 519 | 247 | 19454 | 5460 |
MRPS34,CDK1,CTDSP1,RPLP0,RARS1,PSMC4,RPS14,EEF1E1,PDHB,SMC4,RPL4,FBXW7,MBD3,BRIX1,IVNS1ABP,STK11,XPOT,STK38L,ATP5F1A,NONO,TUFM,LDHA,RPL13A,TECR,STUB1,TUBA1B,RTRAF,ODR4,PTEN,ALB,JOSD1,ILF2,CCT5,CTDSP2,DDX39A,EEF1A1,LBR,EXOSC8,RPL15,THRAP3,FARSA,EGR1,RPS13,RNF20,ARF4,MSH6,PRDX4,RPL23A,RING1,HSD17B10,BRD3,MDM2,HACD3,AIFM1,RPL12,PTPN1,USP39,SLC25A3,WDR77,PSMC1,CMAS,THOC3,ELMO2,ATP1A3,MYO6,YWHAZ,LMNB1,RPS5,HSP90AA1,RMI1,USP13,PRPF31,SAMHD1,MCM3,ACTB,TAB1,RBBP4,SPINDOC,TUBB,SNRPB2,RPL19,PELO,SNRPD1,SNRPD2,RPS9,RPN1,EZH2,RPS11,PPP2R1A,RPL29,ERLIN2,LASP1,ETFA,MCM6,SLC25A5,AKT2,SCYL2,HSPD1,HNRNPA2B1,PCNA,JAK1,RPS24,BAG2,PPM1B,AHSA1,HNRNPD,PRDX1,HNRNPA1,ATXN10,SPTAN1,RPL7,NDUFS8,DHX15,RPL9,WDR6,RPL8,PPP2CB,PHB1,XPO5,RPLP1,RPA2,IDH2,HECTD1,KDM1A,HDAC3,STK38,HSPA5,RPL27,TMEM263,NBN,TWNK,EXOSC4,PRDX6,EIF3G,SPOP,TRIM23,DNAJC10,OAT,IGF2BP1,TNFAIP3,MAT2A,AKT1,SLC25A1,RPL7A,CEP70,UQCRC2,RPS3,PSPC1,PSMC5,TAB2,PSMC3,SLC25A24,IPO8,RPSA,TP53,EGR2,H3C1,HNRNPK,CSE1L,RPL17,SLC25A11,EFHC1,SLC16A1,RPL3,DHX9,RPL24,SNRNP70,RPS2,USP15,USP3,USP2,RBM17,CSNK2A1,COPS5,GAPDH,RPS16,CAND1,CDC5L,SYNCRIP,EEF1B2,STT3A,SSBP1,MAP2K1,EIF4B,SRSF2,PHB2,HSPA8,SF3B1,DDX5,EP300,CCT2,PSMD14,SERPINH1,CREBBP,LDHB,HNRNPC,PSMA4,PSMD1,BRMS1,SNRPB,ATP5F1B,MATR3,PSMD4,PSMD6,FBXO22,POLR2B,RPL10,FBXL14,VDAC2,PRMT5,TUBB4B,MTA2,RPL18,RPS23,FBXL7,TUBA1A,TRAF2,RPS7,CBLN4,EEF2,HNRNPF,RUVBL1,RPS4X,PRPS1,RPL31,LSM14A,PABPC1,CCT8,FBXO11,TRIM21,RUVBL2,RTCB,RPL6,PFDN5,XPO1,QPCTL,RPS10,FAM98A,SNRPA1,TCP1,CCT7,HMG20A,HSP90AB1,FBXO31,SIN3A,SRSF1,RBM5 |
| 1.011e-21 | -48.34 | negative regulation of macromolecule biosynthetic process | biological process | GO:0010558 | 2624 | 983 | 18204 | 5365 |
SDCBP,HENMT1,MDM2,MIR671,MIR188,TP53,MAEL,MIR583,MIR1-1,DDX5,NCBP2,PCGF6,ZC3H7A,MIR99B,CNOT8,PCGF2,SAP18,MIR26B,HSPA8,KLF4,TGIF2LX,MIR147A,PAX9,APLNR,TLR4,ZNF692,MIR335,RNF139,MIR638,ZNF668,ZBTB14,MIR195,RPS26,PIWIL1,IFRD2,LHX2,MIR198,DROSHA,MIR1249,HELLS,KLHL22,CDKN1B,IMPACT,SUV39H1,MIR193B,MIR218-2,SUFU,HOMER3,RBM15B,MIR503,MIR212,APOBEC3H,TWSG1,HMGA1,TNF,SHMT1,MIR9-2,BRMS1L,MIR1298,CX3CL1,XCL1,MUL1,NAB2,RBPJ,MIR624,MIR191,PDE12,PHB1,ING1,HMG20A,BCL6,MIR615,HFE,PFDN5,HEXIM2,CDK5,EMILIN1,KDM2A,MIR98,ITGB8,HINFP,FBP1,MIR1296,MIR649,PKIA,MIR628,RIOX2,SUPT5H,LSM14A,MIR105-1,NDN,CDKN1A,MDFI,MIR16-2,SDR16C5,EID2,PHF12,MIR338,NAB1,TYMS,CITED1,MIR301A,RB1,ZHX3,GJA1,PPM1D,MIR502,MIR214,MIR17,H2AB1,NLRP3,PAIP2B,MIR764,CASC3,CLDN3,FOXC2,H1-5,PDCD1LG2,MIR552,RORB,RPS14,MIR605,MIR200A,EPHA4,MOSPD1,MIR3173,MIR942,MIR7-2,MIR761,MIR484,MAGEH1,FLCN,MIR302B,SFRP1,AGO1,CRYAB,ID1,MIF,CCL3,HNF1B,MIR132,IL12A,LILRB1,BTN2A2,CSF2,BARX2,HEY2,IRF3,SRSF12,MIR1225,KLF12,MIR876,MIR101-2,CHID1,TYROBP,CPTP,MIR661,ZBTB17,MIR760,FURIN,MIR452,LANCL2,MIR150,ING2,DKK3,RUVBL2,BEND6,THAP1,IL20RB,SOCS5,IL4,MIR504,NPTN,MIR662,CD46,MIR149,SCML1,MIR146A,DGCR8,NKRF,MIR346,MIR449B,RLIM,MIR370,LRP3,MIR192,MIR597,RERE,TLE1,OTUD7B,MIR9-1,LSM2,MIR517B,MIR30D,DKK1,MIR600,DHX9,MIR367,MIR25,RNF8,THAP7,STAT6,CCR7,HAND2,MBD3,MIR1226,BHLHE40,SRSF7,HCFC2,DDX4,ZNF345,CD200R1,MIR29C,TSN,EIF4EBP2,MIR339,NR1I2,KDM1A,TRIM29,PELO,SAP30L,MIR936,TOB2,HDAC5,MIR511,CCR1,PRMT2,IRF8,MIR488,MIR558,DHRS7B,IL1R2,RGN,GHRL,MIR551B,CPEB1,CSNK2A1,EXOSC4,MIR429,SOX9,NDFIP1,MIR489,ZCCHC7,SNAI2,DICER1,BANF1,IKZF5,IGBP1,CNOT6,MIR215,DLG1,PIK3CA,APEX1,CBX7,MIR139,PDCD4,SUPT4H1,STAU1,ETV6,MIR143,MIR15A,MAGOHB,H1-3,MIR891B,MIR572,KLF3,CCDC85B,ELK3,EID1,MIR140,HNRNPA2B1,MIR939,FASLG,NSMCE3,MIR137,MIR769,MIR455,NUDT16,MIR298,EIF3E,MIR194-2,PPM1B,MIR532,MTA2,IL23A,MIR652,VEGFA,SATB1,MIR874,CCAR1,MIR944,NR2E1,RAN,MIR24-2,NR0B1,CUL3,MIR922,MIR301B,MIR30E,MAGED4B,FOXP2,YWHAZ,MIR218-1,SOX14,H2AJ,ELK4,NIBAN2,CRYM,MIR493,NIF3L1,MIR363,VSIR,MIR101-1,TNRC6C,MAGEA4,ASB1,CNOT6L,RASD1,NR1I3,HNRNPL,ACVR1B,TMBIM6,MAGEB1,MIR616,FBXW7,MIR208B,NOG,SGF29,HDAC6,APOBEC3C,ALKBH4,MALSU1,MIR592,CCAR2,MIR129-2,NPPC,IGF2BP1,MRTO4,H2AC25,MIR7-1,PSMC5,RBM42,POU1F1,PDE2A,CIART,MIR16-1,C1D,APOBEC3A,MRPL13,H2AC1,RPS13,MIR183,MIR373,PIAS1,TBK1,XRCC5,MIR32,ZBTB39,MIR632,MACIR,MAGEC2,NKX3-2,MIR223,TP53INP1,ZBTB2,MIR379,EIF4E,IL6,ID4,PYDC2,BAHD1,LSM5,CHMP1A,SOX21,PPP2CB,COPS2,HMX1,FOXP3,CD274,MIR1224,PRNP,MIR130B,MIR589,LMNB1,MIR607,SMARCE1,DAPK3,MAD2L2,PAX6,ZBTB33,MIR204,MIR577,MIR423,WNT10B,TXNIP,NMI,FOXS1,UCN,ANXA4,MIR887,MIR454,PLCB1,KCNIP3,HDAC3,MIRLET7D,MIR196B,ZNF24,MIR148A,ZBTB16,SMG8,E2F6,MIR383,MIR580,RPL10,NACC2,SFN,DNAJB6,MIR96,IFNA2,CDC73,MIR648,FABP4,IGF1,MIR604,SAP30,PTRH2,CNOT2,PPP1R11,MIR331,MIR675,TCF23,CALR,SKIC8,SIRT7,MIR639,TNFAIP3,RBBP4,TXN,BAK1,VDR,GSTP1,MAX,MXI1,INPP5E,CCND3,MIR345,MIR877,MIR374A,MIR182,PPP3CA,CLP1,AKT1,MIR569,SIAH2,TGFB3,DUSP26,EXOSC8,TLR6,MIR595,MIR211,TCEAL1,E4F1,PHC1,TSG101,MIR125A,NR1H2,ACP5,MIR187,MIR450B,MIR448,MIR10B,RPL13A,MIR631,MIR320A,MIR1251,HIRA,CCND1,PHF1,PAIP2,MIR130A,MIRLET7B,UBE2D1,AR,MIR492,MIR133B,CXCL8,TAF7,IDO1,ZNF451,MIR770,VPS72,MITF,MIR216A,MIR34A,IL13,MIR609,UBE2D3,MIR340,ATXN1L,FGFR1,NKAP,HELT,PIWIL4,SIX5,MIR155HG,ENC1,SMG9,PTPN11,MIR590,CDK6,DNAJC2,NONO,POLE3,MIR586,TRIM27,DDIT3,NR4A2,MIR28,RAD21,LSM6,EPO,GAPDH,MIR934,EGR1,MIR422A,MKKS,CNOT7,YTHDF2,ESR2,MIRLET7G,MIR1262,EZH1,CHRNA7,MIR554,EZH2,UPF3B,BTG2,UFD1,ZBTB6,TSPO,MIR193A,DCP2,GPNMB,SLA2,MIR711,SESN2,MIR106A,PGR,MIDEAS,PPARG,MIR626,PTGER4,MIR30A,RPL23,MIR636,DDRGK1,ADIPOQ,LBH,MIR505,RBBP7,SRSF2,YAF2,MIR611,MIR567,H2AZ1,IL10,MIR640,ROCK2,FERD3L,STN1,NMBR,TAGLN3,NKX6-2,MSX1,CBX5,MIR145,CX3CR1,FOXP4,ETF1,RPS3,TRIM6,MIR495,HMGB1,CXXC5,EPHA2,RGS2,MIR875,GABPA,AGER,ZNF304,MIR361,MIR23A,PYCARD,HRAS,INPPL1,PSMD10,APOBEC3B,H2AX,ZBTB45,SPINDOC,FBXW11,MIR424,DAP,ADNP,DIS3L,TFDP2,XAF1,EIF4E2,LDB1,CGGBP1,MIRLET7C,F2,MIR657,MIR581,ACOT8,MIR1277,MIR106B,ITM2A,WWP2,DLX1,MIR216B,HNRNPA1,MYC,MIR184,MIR126,CREB1,MIR553,DAPK1,MIR556,TDRD7,MIR490,APOBEC3G,MIR142,MIR105-2,APOBEC3D,CD83,MIR190B,INPP5K,APLN,SNIP1,MOV10,CDK1,OSR2,RPS6KA4,MIR194-1,SMAD5,MIR557,EED,NFIL3,TGIF2,CDK5R1,H2AC13,MAGED2,MEPCE,RBBP8,CAV1,TRIM11,IFNB1,SMG5,RBFOX2,RC3H2,VGLL4,CBFB,CD28,BEND5,MEF2C,MIR208A,PKIG,ZMYM2,ZMPSTE24,RUNX1,GFI1,WWP1,SMAD2,MIR342,BRCA1,MIR31,APOBEC3F,ZGLP1,UBE2I,ZHX1,MIR324,HBEGF,AP2A1,ZBTB42,PSEN1,LILRB4,ARB2A,NOTCH2,TGFB2,CRYBA1,MIR144,MIR612,PCNA,RING1,ZBTB38,NCK1,MXD1,GCLC,TRIM37,IRF2,SOX2,PTPN22,DYRK1A,HSBP1,ZNF177,PIWIL2,MIR152,MTDH,PROX1,CREBBP,GREM1,MIR147B,MIR940,ZBTB18,MIR200C,ATP2B4,MIR425,SMAD1,IRF7,NLRP6,MIR1260B,ZBTB26,XPO5,MACROH2A1,MIR708,ZNF174,CTBP1,SHC1,SUMO1,HNRNPC,OAS1,TWIST2,MIR656,TRIM22,MIR20A,TADA3,CIRBP,PYM1,PICALM,MAFG,MIR34B,TENT2,BIRC5,ZBTB5,MIR873,MIR7-3,IFNG,HOXB8,PRKRA,MEF2A,MIR135B,LGR4,MIR765,SRGN,NRDE2,MIR34C,SRC,PPID,SMARCA5,PIWIL3,ANGPT1,MIR148B,HEXIM1,ZNF175,PHB2,MIR601,CD200,ATF4,POLR2G,SQSTM1,LEP,HNRNPK,PRMT6,SOX3,DNAJB4,BMPR1A,MIR181C,MIRLET7I,MECP2,DRAP1,MIR549A,EDC3,MIR29A,EXOSC3,SRSF4,MIR542,MIR625,GTF2IRD1,MIR100,TRIM3,BRMS1,ITM2B,IRF1,INSM2,IFI16,MIR296,MYT1L,CIPC,TLR8,MIR563,MIR618,CCDC3,MIR551A,CTNNBIP1,MIR153-1,EIF4EBP3,TCEAL7,METTL14,NR2F6,MAGEB10,SCML2,MIR24-1,SMAD3,DUSP22,HNRNPD,TUSC2,SERPINB1,PNRC1,MIR920,EIF4A3,IRF2BP1,ELOC,MIR23B,MIR205,SETD5,MIR599,MIR924,MACROH2A2,KLF10,PCGF3,NKX3-1,NFKBIL1,ATF3,FCGR2B,MIR653,IRF2BPL,HCLS1,PSPC1,PML,EIF2S1,ARG2,NFKB1,MIR141,MIR491,TERT,SNAI3,LRIF1,PABPC1,MIR937,CD2AP,CD38,MIR1180,MIR181D,NUDT12,MIR802,GADD45A,TRAF6,MIR222,ZBTB25,SFTPD,H2AZ2,MIR378A,PLAGL1,THRAP3,FOXP1,MIR190A,MIR185,PCBP4,LDB2,IL12B,ERP29,USP2,MIR1-2,RFX5,CSK,MIR633,MIR107,MIR186,JUN,MORC2,ENO1,LDLR,CBX3,DMAP1,MIR885,MTA3,MIR10A,MIR449A,ZNF263,PPARA,LYAR,PC,SIN3A,IFI27,MIR210,BAP1,MIR129-1,MIR593,CD36,MIR33B,SRSF10,FOXD3,MIR197,POU5F1,TCF21,DXO,MIR651,ABCC2,MIR548C,MIR330,SYNCRIP,RGCC,TIA1,MIR375,CPNE1,MSX2,WDR82,ANAPC2,MIR30B,MIR21,INHA,MIR519D,DR1,MIR384,EP300,PDCD10,MAGOH,OVOL1,CTNNB1,SP2,MIR1227,BACH1,H2AC7,TSNAX,ANXA7,LMNA,ZMYND11,MIR1271,EID2B,GMNN,MIR578,NOP53,MIR938,MIR136,PRMT5,MIR99A,LSM4,RNF128,MIR92B,H2AC6,MIR9-3,SMAD4,SELENOS,MIR500A,MCPH1,MAF1,USP3,BST2,MIR573,STAT1,CRY1,GSK3A,DEFB114,DEDD,CD34,SMCHD1,AATF,MIR377,CREBZF,SNX12,LMO4,EIF2AK2,MIR206,MIR643,H2AC4,PHF21A,MIR155,MIR221,TRIM24,MIR497,NCOA5,CRKL |
| 1.038e-21 | -48.32 | COPS5 (COP9 signalosome subunit 5) | protein interactions | 10987 | 1060 | 438 | 19454 | 5460 |
RIT1,MYO6,BLVRA,GGH,MCM3,MCM4,NOP16,CUL2,CUL3,GNB1,BTG3,SNRPB2,RPL19,RPL35,DYNLL1,EDNRA,RPL37A,EIF3K,PELO,FAU,CPSF1,ATP5PO,PPARG,ETF1,PRDX3,SKP1,G3BP2,HAND2,NMRAL1,FBXW4,UPF3B,RPL23,CDKN1B,RNF139,FEM1B,TRA2A,PRPF19,PRDX1,KCTD10,SNX2,CCAR2,SPTAN1,RPL7,COPS7B,GATD3,COPS2,RPLP1,PHB1,WDR6,PLD3,GTPBP1,TULP3,TXNRD1,RFC2,MCM6,G3BP1,LASP1,UBE3A,RPS24,MEF2C,STK11,NCKIPSD,PEA15,TXNIP,DCAF16,KPNA6,NONO,USP14,TUFM,PPP1CC,ATP5F1A,CSK,CREB3,SMAD5,RPL22,SLC25A4,ARMC6,TXN,ACAT1,CFAP298,RPS20,RTRAF,MTRES1,RPLP0,HSP90B1,JUP,RPS14,FBXO9,RPL4,SIRT7,PRPF4,CRBN,KLHL9,NFKB1,POLR2I,TOP1,EHBP1,SRPRA,SRP14,AIFM1,MRPL49,PPP4C,ILF2,PPME1,RPL15,SLC29A1,EEF1A1,YTHDF2,MRPL11,CCDC47,SNRPG,MDC1,RPS13,OLA1,HSD17B10,FTSJ3,COPS7A,PPP5C,SNRNP40,FBXO22,ANAPC2,SF3B4,GRIK1,FBXO42,RPL27A,PITHD1,STAU1,HNRNPA0,EMC1,EP300,STK26,HSPA8,SNRPA,HSPB1,STAMBPL1,DCAF5,IKBKB,NT5C2,CENPW,GSTM3,LYAR,TCP1,FAM98A,EIF2S1,PGR,MAGED2,S100A8,SRSF1,MPDU1,FBXO31,RPL18,KLHL12,RHOBTB1,IRF8,TNPO2,TRAF2,MAX,ERRFI1,HNRNPDL,RPL28,NUP42,KRAS,PDIA6,RTCB,FBXO11,RBM3,CCT8,PABPC1,KLHL23,DNAJC10,EIF3G,PCBD1,TIA1,RPS17,MAT2A,NAA50,MYG1,RPL10L,BUB3,PSMC5,PSMA6,PAFAH1B3,RPS3,HECTD1,GSTP1,UBE2M,RPA2,SPTBN1,HSPA5,H2AC13,HNRNPH2,APMAP,USP15,RPL10A,RPS2,SNRNP70,SMAD4,KLHL22,COPS5,CSNK2A1,KARS1,CDC5L,RBM42,LRRC14,RPS16,SDHB,SYNCRIP,STT3A,CD274,TFRC,ACTR1A,CDK4,RRM1,FKBP8,KPNA2,CAMKV,ERO1A,RPL3,BACE1,ILK,BAX,PFDN2,HSP90AA1,YWHAZ,DCAF4,PRPF31,OPRM1,RAB11A,USP5,ACTB,SIAH1,TENT5C,TUBB,PRDX2,RPS9,SEC61B,SNRPD1,SNRPD2,ANXA7,SLC25A3,LARP4B,DET1,TOR1AIP2,PGRMC1,SRM,PAFAH1B2,UCHL3,CYFIP2,EMG1,DCAF11,HNRNPD,SKIC8,HNRNPA1,PLAC8,PDIA3,DHX15,PPIA,RPLP2,RPL9,RPL8,SNRPE,SART3,RPS11,POLR2C,RPN1,SKA3,PPP2R1A,JUN,ARFGAP1,CKS1B,RAF1,AHCYL1,SACM1L,SSRP1,COPS4,PSMD12,MRPS11,SRSF7,PRPSAP1,HNRNPA2B1,SLC25A5,MAP3K11,CIPC,HSPD1,MAPRE1,YPEL5,SMAD2,FBXO7,DEK,VIRMA,MGST3,GNPDA1,SYT2,CTTN,TUBA1B,ENO1,CTNNA1,HNRNPH3,RPL26L1,STOM,CCNA2,SEC22B,CHMP2B,RPA3,SPP1,HM13,H2AC14,MOV10,MRPS23,MDM2,DCUN1D1,ACTA2,PTPN1,RPL12,PDE6D,KLHL26,APBB3,KLHL15,RPL23A,CPNE2,NKRF,PPP1R12A,YAE1,COP1,FBXW11,MRPS25,CIRBP,CCT2,SNRPB,HNRNPC,LDHB,SFN,HNRNPAB,NCKAP1,KBTBD6,RPL10,PSMB6,STAT1,MATR3,FBXL14,CNDP2,CSNK1A1,NUFIP2,EEF1G,TRA2B,SRSF2,NDUFS2,DDX5,RAMAC,SF3B1,JAGN1,PEBP1,DDX1,AK2,CTNNB1,YWHAG,RPL6,DCAF4L2,HSP90AB1,TRMT61A,SUMO3,SNRPD3,OSBP,HNRNPL,RPS10,FUBP3,RBM5,GYS1,SIN3A,RPS23,SMARCB1,TUBB4B,RPS7,EEF2,ANAPC13,TRMT1L,TFG,RPS4X,RUVBL1,FEM1C,PSMA1,HNRNPF,EWSR1,MYO1B,ABCF1,RPL31,FBXO3,DTL,IGF2BP1,FBXO44,NUDT1,SMARCA5,UBA3,CDC20,MAP3K3,MACROH2A1,PTPMT1,RCBTB1,CALML5,PHAX,CDIPT,LUC7L3,AGO1,RPS15,DLAT,PGK1,LSM12,RPL27,KPNA1,H2AC4,RPL24,NR4A2,ELOC,GAPDH,MIF,KCTD3,CAND1,CPNE1,ALYREF,RPL32,SSBP1,BIRC5,NUPR1,RAD1,CAPN2,MINDY3,DDX42,CENPM,RPSA,TP53,KBTBD4,STRBP,RPL17,HNRNPK,PDE12,NEDD8,DHX9,KLHL24 |
| 2.655e-21 | -47.38 | organelle envelope | cellular component | GO:0031967 | 1267 | 520 | 19108 | 5553 |
C9orf72,BAX,LMNA,AGPAT5,PTRH2,LMNB1,MRPL50,SURF4,EXD2,GNAZ,ENY2,RTN4,NUP50,CBX5,CHCHD2,RAN,TAMM41,UCP2,NUDT1,HADHA,TRA2B,UBE2I,BANF1,ADCK1,HINT2,NLRP6,MRPL20,SMAD3,COQ8B,ATP5F1D,APOO,CYP27A1,MRPL49,XPOT,SLC25A27,KRAS,SLC25A42,OTULINL,MRPS34,COX17,COX10,BAD,MGST2,TMX2,CCND1,NRP1,MRPL12,ALPL,MRPS35,CYB5A,ARMCX3,HAX1,NDUFAF3,CISD1,MAD2L1BP,MRPL10,CALR,COX6B1,NDUFS3,DNAJC30,CIBAR1,PRICKLE2,CSE1L,GLE1,FIS1,SLC25A28,TOMM22,CHCHD3,WDR3,STX1A,HTRA2,MCL1,ARL2BP,SUMO1,CPT2,CHMP2A,MPV17,TMEM170A,BRAP,MRPL24,FAF1,GHITM,ATG9A,ENO1,STOML2,PGRMC1,CD38,DES,VPS4A,LYPLA1,RANBP1,XPO1,THG1L,ACSL4,PDSS2,GPX4,DUSP18,TMEM126A,ARMCX2,AGK,SORD,SYNJ2BP,MRPL41,GRPEL2,SRSF1,SPHK2,CHMP2B,MRPL9,COX8A,ZMPSTE24,SRC,OSBPL8,COX6A2,SLC25A44,NXT2,RAC2,CDK4,NUDT9,TMEM176B,MAD2L1,KCNH1,DUSP21,NUP153,TRAF3IP3,TMEM11,NDUFS2,NDUFA4,FUNDC1,SEC13,TMEM209,DCAKD,NUP37,RRM1,TIMM23,PTGES,SLC25A12,PDE2A,VPS4B,DEGS1,PARL,MRPL40,CCNI,CACYBP,PLPP6,IMMP2L,TNPO3,RPS27A,MX2,CLPX,COX4I2,BECN1,MAP1LC3B,PGR,PPIF,INPP4A,ROMO1,SOD1,SLC25A21,MRPL52,IL15RA,NUP62,SLC25A45,UBB,MPV17L2,RBMX2,TIMM8A,TOMM6,SMAD1,RAF1,MRPS16,H2BW1,SLC11A2,NDUFB5,HACD3,TMEM177,TOMM20,ATP5PO,ABCG2,SLC25A1,BCL2L1,NDUFB4,UQCR11,TIMM10,DNAJC1,SLC25A39,SMCP,MTX2,MTDH,MGST3,CPT1B,SLC25A14,SYNE4,PLN,GNAQ,RETSAT,DNAJB2,CHCHD4,MYO6,RNASET2,ATAD1,TMBIM6,SLC25A23,UQCRQ,SLC25A24,MATR3,FZR1,CHMP1A,TYMS,SNN,VDAC1,COX7B2,UFL1,ZDHHC8,SLC25A3,CYP27B1,CCAR1,ATRAID,PRKCA,USP30,SLC25A51,CREB3L4,SIGMAR1,ALOX5AP,CYB5B,MARCHF5,CHMP1B,SLC25A31,CNP,BCS1L,RMDN3,CHDH,NDUFB6,ATP5PF,RBM15B,CHMP5,TAFAZZIN,MRPL23,KGD4,FAM156A,GABBR1,SAMM50,MRPS26,TMEM14A,DMPK,MRPS11,SLC25A26,NDUFAF2,HIGD2A,FAM169A,EI24,FKBP10,BICD2,CLPB,SDCBP,STAR,NDUFA12,ATP5MK,RSAD2,MRPS18A,ADRA1A,MTMR6,LDHB,MYORG,ARMCX1,NXT1,COX6C,MRPS18C,CMC4,UBA52,CPTP,SLC39A9,COX11,TERB2,S100A6,CYP11B2,RAB32,MRPL33,MAIP1,HSPD1,IPO8,SLC25A10,MPC1,RTCB,TSPO,IFI27,ATP5F1A,UQCRC1,SLC41A3,SFXN1,TIMM13,NDUFB8,MNS1,RPS3,CHCHD6,SLC25A20,ELAVL4,AURKAIP1,FBXW11,TUBB,SEPHS1,RB1CC1,UQCC3,GRPEL1,MIEF1,FGR,MTCH2,NDUFA1,TMEM97,MRPL17,LGALS3,PNPLA8,SLC25A46,RNF144B,NDUFS8,TIMM8B,CLU,VAMP1,NRM,TIMMDC1,TMX4,TOR2A,TMEM70,REXO2,PRNP,WTAP,STARD13,MFN1,THAP7,MRPS9,COX6B2,MRPL51,PMAIP1,MRPL57,GPAM,CD2AP,TNKS2,CETN2,KPNA1,UQCC2,MGARP,PAK5,PTPMT1,COX16,TMEM38B,TOR3A,GNPAT,KCNJ11,ZBED1,AK2,CBX3,UNC50,TENT4A,CETN3,PARP11,TOMM40,CPNE1,PLA2G4B,PSEN2,MTG2,LEMD3,COX4I1,TNKS,PMPCA,CRAT,NDUFB10,TMEM147,MACO1,TWNK,MRPS23,ELK1,NOC4L,PLCB1,CNR1,SLC25A5,MUL1,MTARC2,MRPL16,PHB2,TOR4A,PAFAH1B1,TOR1B,APEH,GTF3C3,UBIAD1,PLAAT3,ATP5MC3,TUFM,BAK1,ATP5MG,RNF5,NUP42,MRPL18,TOMM70,COX14,CYP1A1,NGRN,SFXN2,SARM1,TRMT10B,CARD19,DNAJC19,CCDC90B,QTRT2,COX5A,MRPS7,MT3,KLK6,TRIM27,NDUFA2,MRPS17,MRPL47,NOS1AP,TIMM17A,ABHD6,ATP5F1E,TMEM33,UQCRC2,ARMC1,MRPL53,NDUFV2,PPP1CC,CYC1,PSEN1,SLC25A4,CYP11B1,CASC3,MRPL36,TMEM168,FAM162A,GCHFR,TOR1AIP2,PHB1,DELE1,SDHC,TIMM21,TOMM7,NDUFS6,ATP5F1B,DNAJC2,PRELID1,FUNDC2,SLC25A32,LBR,COQ10B,SDHB,SMDT1,TMEM126B,CHCHD1,GPD2,NDUFAB1,ROGDI,CHMP4C,MRPS18B,ANXA4,VDAC2,EPHA4,PTGDS,TIMM29,CYB5R3,MRPL22,TOMM40L,HSD17B8,BCL2A1,BOK,COX20,TMEM160,ATP5MC1,COA4,NDUFB7,AIFM1,AKAP1,ATP5PD,GAPDH,NUP107,NUP35,UQCRH,KPNA2,DTL,ABCF1,COA1,UQCC6,MRPL11,GK2,MRPS21,MX1,MRPS28,STARD7,MRPL34,SH3GLB1,MRPS25,NDUFA5,COX7B,TMEM14B,MTG1,SLC52A3,SLC25A11,NDUFC2,MTHFD2L,MRPS33,ARL6IP6,ATP5PB,FATE1,MAVS,PGS1,BNIP3L,NME4,FBXL4,TMPO,EFHD1,IFI6,PLSCR3,PTPN1,NOA1,NDUFAF4,COX7A1,MINDY3,NDUFAF6,MRPL13,FKBP8,COX19 |
| 2.805e-21 | -47.32 | translation repressor activity | molecular function | GO:0030371 | 324 | 178 | 18094 | 5411 |
MIR132,MIR25,MIR34C,MIR106B,MIR221,MIR190B,MIR92B,MIR133B,MIR186,MIR206,MIR212,MIR384,MIR379,MIR503,MIR15A,MIR153-1,MIR638,MIR640,MIR192,MIR423,MIR139,MIRLET7G,MIR211,MIR708,MIR129-1,MIR361,MIR639,MIR152,MIR920,MIR32,MIR16-1,MIR99B,MIR519D,MIR3173,MIR488,MIR449A,MIRLET7I,MIR200A,MIR495,MIR200C,MIR107,MIR675,MIR193B,MIR29C,MIR130B,MIR135B,MIR1224,MIR205,MIR1271,MIR873,MIR215,MIR383,MIR155,MIR33B,MIR378A,MIR126,MIR338,MIR373,MIR26B,PAIP2,MIR187,MIR425,MIR210,MIR218-1,MIR939,MIR29A,MIR150,CPEB1,MIR24-1,MIR877,MIR193A,MIR188,MIR448,MIR130A,MIR769,MIR20A,MIR28,MIR194-1,MIR301B,MIR144,MIR30B,MIR181D,MIR876,MIR204,EIF4EBP3,TYMS,MIR657,MIR625,MIR195,MIR374A,MIR874,MIR302B,MIR490,MIR1-1,MIR23A,MIR9-1,MIR148A,MIR208A,PAIP2B,MIR101-1,MIR191,MIR661,MIR491,MIR10B,MIR183,MIR147A,MIR222,MIR340,MIR335,MIR511,MIR572,MIR208B,MIR552,MIR142,MIR182,MIR146A,MIRLET7C,MIR492,MIRLET7B,MIR301A,MIR106A,MIR342,MIR143,MIR590,MIR141,MIR363,MIR137,MIR493,MIR296,MIR455,MIR149,MIR320A,MIR21,MIR429,MIR330,MIR198,MIR100,SHMT1,MIR424,MIR345,MIR125A,MIR223,MIR339,MIR573,MIR105-1,MIR30A,EIF4EBP2,MIR551A,MIR148B,MIR214,IFRD2,MIR1260B,MIR505,MIR10A,MIR34A,MIR96,MIR30D,MIR1277,MIR145,MIR181C,MIR185,MIR34B,MIR497,MIR98,MIR30E,MIR1298,MIR298,MIR548C,MIR99A,MIR31,MIR17,MIR140,TRIM3,CIRBP,MIR885,MIR136,MIR346,MIR454 |
| 2.980e-21 | -47.26 | VCAM1 (vascular cell adhesion molecule 1) | protein interactions | 7412 | 469 | 227 | 19454 | 5460 |
SLC2A1,ESYT1,PSMB1,RPL12,MRPS23,TOP1,EEF1A1,BCS1L,CCT5,YTHDF2,ILF2,NDUFS3,ACTR2,VTA1,PDE2A,RPS13,EIF3E,HSPE1,ATP5F1A,RPL26,GMPS,TUFM,NONO,PYCR2,AP2A1,NAPA,MAPRE1,RPS20,MSN,ACAT1,RPS12,ENO1,SMAP2,TUBA1B,EIF4A3,UBB,DDAH2,RPL22,LDHA,RPL13A,SNX3,RPS14,HNRNPH3,RARS1,RPLP0,LMNA,CDK1,PICALM,H2AC7,STOM,PPIH,H2BC12,INPPL1,RPL4,PIK3R2,HNRNPA1,RAP2B,EIF3D,PRDX1,PSMD3,HNRNPD,PDCD10,RPL23,HBA1,TYMS,XPO5,KRT8,THOC2,RPL8,RPL9,DNM2,PHB1,PPIA,CACYBP,DHX15,RPL7,PPP2R1A,ACTN4,LYPLA1,NAA15,RPS11,AP2S1,RPN1,RPS24,ZYX,HSPD1,HNRNPA2B1,RPS27A,MCM6,SSRP1,ANP32B,G3BP1,MCM4,MCM3,ACO2,HSP90AA1,RPS5,ATP1A3,LMNB1,YWHAZ,SNRPD2,AP2M1,SNRPD1,RPS9,SEC61B,ARF1,RAN,GNB1,PRDX2,TUBB,RPL35,ACTB,PRDX3,H1-5,MYL6,ATP5PO,PSMA3,SRM,SRI,ZFAND2B,GAPDH,USP2,RPS2,RPL10A,RPL24,SNRNP70,RAP1B,TRAPPC3,RAC2,EEF1B2,SYNCRIP,UBE2N,ALYREF,CCL17,RPS16,MIF,SNAP29,RPSA,TFRC,ARPC3,RPL3,DHX9,RPL17,CAPZA1,PSMA5,KPNA2,CSE1L,HNRNPK,RPS17,CFL1,TIA1,PSMB2,RPL7A,PTPN11,IGF2BP1,CSNK2B,PSMC5,SF3B6,RPS3,PAFAH1B3,PSMA6,TRIM54,BUB3,CD2AP,NTPCR,CAPN1,UBE2M,GSTP1,SDCBP,H2BC11,PRDX6,MARS1,XPO1,RAB5C,DDX1,HSPB1,YWHAB,DRG1,FKBP4,CORO1C,FUBP3,HSP90AB1,CCT7,EIF2S1,HNRNPL,RPS10,TCP1,SNRPA1,H1-3,EEF2,RPS7,RANBP1,RPL18,TUBB4B,RUVBL2,EFNB1,EWSR1,CCT8,PABPC1,VAMP8,RPS4X,IL13,HNRNPF,PTPN4,VDAC1,HNRNPC,LDHB,CCT2,PRMT5,VDAC2,PSMB6,RPL10,TAGLN2,ATP5F1B,SYK,RPL27A,CSNK1A1,HBE1,HSPA8,DDX5,DDX39B,RPS28,XRCC5,LYPLA2,HNRNPA0,EEF1G,PHB2 |
| 3.197e-21 | -47.19 | negative regulation of cellular biosynthetic process | biological process | GO:0031327 | 2666 | 994 | 18204 | 5365 |
MIR30E,MAGED4B,FOXP2,YWHAZ,MIR301B,MIR922,MIR24-2,CUL3,NR0B1,MIR944,NR2E1,RAN,MIR493,CRYM,NIBAN2,MIR218-1,SOX14,H2AJ,ELK4,PPM1B,MIR532,MIR455,MIR298,NUDT16,EIF3E,MIR194-2,MIR137,MIR769,NSMCE3,SATB1,MIR874,CCAR1,MIR652,VEGFA,MTA2,IL23A,ELK3,KLF3,CCDC85B,H1-3,MIR891B,MIR572,INSIG2,FASLG,MIR140,HNRNPA2B1,MIR939,EID1,APEX1,CBX7,PIK3CA,ETV6,MIR143,MIR15A,MAGOHB,SUPT4H1,STAU1,MIR139,PDCD4,H2AC1,RPS13,MIR183,MIR373,MRPL13,C1D,APOBEC3A,MIR32,ZBTB39,MIR632,TBK1,XRCC5,PIAS1,PDE2A,CIART,RBM42,POU1F1,H2AC25,MRTO4,MIR7-1,PSMC5,NPPC,IGF2BP1,MIR16-1,TMBIM6,HNRNPL,ACVR1B,NR1I3,MALSU1,MIR592,CCAR2,MIR129-2,APOBEC3C,ALKBH4,MIR208B,NOG,SGF29,HDAC6,MAGEB1,MIR616,FBXW7,MIR101-1,MIR363,VSIR,NIF3L1,CNOT6L,RASD1,ASB1,MAGEA4,TNRC6C,MIR383,RPL10,MIR580,MIR148A,ZNF24,ZBTB16,SMG8,E2F6,HDAC3,MIRLET7D,MIR196B,PLCB1,ORMDL1,KCNIP3,MIR648,FABP4,MIR96,IFNA2,CDC73,SFN,DNAJB6,NACC2,WNT10B,TXNIP,NMI,FOXS1,ZBTB33,MIR204,MIR577,MIR423,PAX6,MAD2L2,MIR454,MIR887,ANXA4,UCN,MIR1224,HMX1,FOXP3,CD274,COPS2,PPP2CB,KLHL25,DAPK3,SMARCE1,MIR607,MIR589,LMNB1,PRNP,MIR130B,ERLIN2,NKX3-2,MIR223,MACIR,MAGEC2,CHMP1A,SOX21,PYDC2,LSM5,BAHD1,IL6,ID4,TP53INP1,ZBTB2,MIR379,EIF4E,MIR320A,MIR631,MIR1251,RPL13A,MIR492,UBE2D1,AR,MIR130A,MIRLET7B,HIRA,CCND1,PAIP2,PHF1,MIR187,NR1H2,MIR125A,ACP5,PHC1,TSG101,TCEAL1,E4F1,MIR10B,MIR448,MIR450B,SIAH2,TGFB3,AKT1,MIR569,CLP1,PPP3CA,MIR374A,MIR182,MIR595,MIR211,EXOSC8,TLR6,DUSP26,CALR,SKIC8,MIR639,SIRT7,MIR331,MIR675,TCF23,CNOT2,PPP1R11,IGF1,SAP30,MIR604,PTRH2,MIR345,CCND3,MIR877,MXI1,INPP5E,TXN,BAK1,VDR,GSTP1,MAX,TNFAIP3,RBBP4,SUFU,HOMER3,MIR193B,SUV39H1,MIR218-2,CDKN1B,IMPACT,HELLS,KLHL22,APOBEC3H,MIR503,MIR212,RBM15B,ZBTB14,CYP27B1,MIR638,ZNF668,ZNF692,MIR335,RNF139,MIR198,DROSHA,MIR1249,LHX2,IFRD2,MIR195,RPS26,PIWIL1,HSPA8,PCGF2,SAP18,MIR26B,CNOT8,MIR99B,TLR4,APLNR,TGIF2LX,MIR147A,PAX9,KLF4,TP53,MAEL,MIR583,MDM2,MIR671,MIR188,SDCBP,HENMT1,PCGF6,ZC3H7A,LEPR,NCBP2,DDX5,MIR1-1,PAIP2B,MIR764,NLRP3,MIR502,MIR214,MIR17,H2AB1,GJA1,ZHX3,PPM1D,MIR552,PDCD1LG2,FOXC2,H1-5,CASC3,CLDN3,CDKN1A,MDFI,SDR16C5,MIR16-2,NDN,MIR105-1,LSM14A,RIOX2,SUPT5H,CITED1,RB1,MIR301A,TYMS,NAB1,EID2,MIR338,PHF12,HEXIM2,CDK5,BCL6,MIR615,HFE,PFDN5,HMG20A,ORMDL3,MIR628,PKIA,ITGB8,HINFP,FBP1,MIR1296,MIR649,EMILIN1,MIR98,KDM2A,MUL1,XCL1,NAB2,RBPJ,BRMS1L,CX3CL1,MIR1298,TNF,SHMT1,MIR9-2,TWSG1,HMGA1,PHB1,ING1,PDE12,ATP1A1,MIR624,MIR191,IL4,MIR504,NPTN,MIR662,IL20RB,SOCS5,BEND6,THAP1,MIR146A,DGCR8,NKRF,SCML1,CD46,MIR149,FURIN,ZBTB17,MIR760,TYROBP,MIR661,CPTP,MIR876,CHID1,MIR101-2,ING2,RUVBL2,DKK3,LANCL2,MIR150,MIR452,LILRB1,MIR132,IL12A,MIF,HNF1B,CCL3,ID1,MIR1225,KLF12,SRSF12,HEY2,IRF3,BARX2,BTN2A2,CSF2,MIR3173,MIR942,MIR7-2,RPS14,MIR605,MIR200A,EPHA4,MOSPD1,RORB,CRYAB,AGO1,MAGEH1,SFRP1,FLCN,MIR302B,MIR761,MIR484,SOX9,NDFIP1,MIR429,GHRL,MIR551B,RGN,CSNK2A1,EXOSC4,CPEB1,DHRS7B,IL1R2,IGBP1,DCAF5,CNOT6,MIR215,DLG1,BANF1,IKZF5,DICER1,MIR489,SNAI2,ZCCHC7,NR1I2,KDM1A,TRIM29,PELO,MIR339,MIR29C,TSN,EIF4EBP2,CD200R1,MIR558,MIR488,MIR511,HDAC5,CCR1,IRF8,PRMT2,SAP30L,MIR936,TOB2,MIR367,MIR25,DKK1,MIR600,DHX9,MIR30D,MIR517B,HCFC2,SRSF7,ZNF345,DDX4,HAND2,MIR1226,MBD3,BHLHE40,RNF8,THAP7,STAT6,CCR7,MIR192,MIR597,LRP3,MIR370,RLIM,MIR346,MIR449B,OTUD7B,MIR9-1,LSM2,TLE1,RERE,INSM2,TRIM3,BRMS1,IRF1,ITM2B,MIR100,MIR625,GTF2IRD1,EIF4EBP3,MIR153-1,TCEAL7,METTL14,CTNNBIP1,MIR563,MIR618,CCDC3,MIR551A,MIR296,IFI16,TLR8,MYT1L,CIPC,MIRLET7I,MECP2,BMPR1A,MIR181C,SOX3,DNAJB4,PRMT6,EXOSC3,SRSF4,MIR542,EDC3,MIR29A,DRAP1,MIR549A,PPID,SMARCA5,PIWIL3,ANGPT1,MIR34C,SRC,SRGN,NRDE2,MIR765,POLR2G,SQSTM1,HNRNPK,LEP,MIR601,CD200,ATF4,MIR148B,HEXIM1,PHB2,ZNF175,MIR7-3,IFNG,ZBTB5,MIR873,TENT2,MIR34B,BIRC5,LGR4,MIR135B,PRKRA,MEF2A,HOXB8,MIR222,ZBTB25,GADD45A,TRAF6,MIR802,CD2AP,CD38,NUDT12,MIR1180,MIR181D,PLAGL1,MIR378A,SFTPD,H2AZ2,PML,HCLS1,PSPC1,IRF2BPL,PABPC1,MIR937,MIR141,NFKB1,SNAI3,MIR491,TERT,LRIF1,EIF2S1,ARG2,KLF10,PCGF3,MIR599,MIR924,MACROH2A2,SETD5,MIR205,MIR23B,MIR653,FCGR2B,NKX3-1,NFKBIL1,ATF3,DUSP22,MIR24-1,SMAD3,MAGEB10,SCML2,NR2F6,IRF2BP1,ELOC,SERPINB1,PNRC1,EIF4A3,MIR920,HNRNPD,TUSC2,RGCC,TIA1,SYNCRIP,MIR548C,MIR330,MIR651,ABCC2,MIR519D,MIR21,MIR30B,INHA,MSX2,WDR82,ANAPC2,MIR375,CPNE1,SIN3A,IFI27,LYAR,PC,FOXD3,DXO,MIR197,POU5F1,TCF21,MIR33B,SRSF10,MIR129-1,MIR593,CD36,BAP1,MIR210,CBX3,DMAP1,MIR885,LDLR,ENO1,JUN,MORC2,MIR186,PPARA,MIR449A,ZNF263,MTA3,MIR10A,IL12B,MIR185,LDB2,PCBP4,MIR190A,THRAP3,FOXP1,MIR107,MIR1-2,CSK,RFX5,MIR633,ERP29,USP2,MIR643,H2AC4,EIF2AK2,MIR206,SNX12,LMO4,AATF,CREBZF,MIR377,NCOA5,CRKL,TRIM24,MIR497,MIR155,MIR221,PHF21A,USP3,MIR573,BST2,STAT1,MCPH1,MAF1,MIR500A,DEDD,SMCHD1,CD34,DEFB114,CRY1,GSK3A,MIR938,MIR136,NOP53,GMNN,MIR578,LMNA,ZMYND11,MIR1271,EID2B,MIR9-3,SMAD4,SELENOS,MIR92B,H2AC6,PRMT5,LSM4,MIR99A,RNF128,OVOL1,PDCD10,MAGOH,MIR384,DR1,EP300,H2AC7,TSNAX,ANXA7,MIR1227,BACH1,CTNNB1,SP2,PGR,SLA2,GPNMB,MIR711,SESN2,MIR106A,MIR193A,DCP2,UFD1,TSPO,ZBTB6,BTG2,RPL23,MIR30A,PTGER4,MIR626,PPARG,CYP7A1,MIDEAS,MKKS,CNOT7,GAPDH,MIR422A,EGR1,MIR934,EPO,NR4A2,MIR28,RAD21,LSM6,MIR554,CHRNA7,EZH2,UPF3B,MIR1262,EZH1,MIRLET7G,YTHDF2,ESR2,MIR155HG,PIWIL4,SIX5,HELT,ATXN1L,MIR340,FGFR1,NKAP,TRIM27,DDIT3,DNAJC2,NONO,CDK6,POLE3,MIR586,PTPN11,MIR590,ENC1,SMG9,IDO1,CXCL8,TAF7,MIR133B,MIR609,IL13,UBE2D3,MIR34A,MIR216A,ZNF451,MIR770,MITF,VPS72,LDB1,XAF1,EIF4E2,DIS3L,TFDP2,MIR581,ACOT8,MIR1277,MIR657,MIRLET7C,F2,CGGBP1,APOBEC3B,PSMD10,INPPL1,ADNP,MIR424,DAP,H2AX,SPINDOC,ZBTB45,FBXW11,RGS2,EPHA2,CXXC5,MIR495,HMGB1,AGER,ZNF304,MIR361,HRAS,PYCARD,MIR23A,GABPA,MIR875,H2AZ1,YAF2,MIR567,MIR611,MIR640,FERD3L,ROCK2,IL10,STN1,SRSF2,ADIPOQ,MIR505,LBH,RBBP7,MIR636,DDRGK1,RPS3,TRIM6,FOXP4,ETF1,MSX1,CBX5,MIR145,CX3CR1,NMBR,TAGLN3,NKX6-2,BRCA1,MIR31,WWP1,MIR342,SMAD2,ZMYM2,ZMPSTE24,RUNX1,GFI1,MIR208A,PKIG,PSEN1,LILRB4,ARB2A,HBEGF,AP2A1,ZBTB42,ZHX1,MIR324,APOBEC3F,ZGLP1,UBE2I,RC3H2,SMG5,RBFOX2,RBBP8,CAV1,TRIM11,IFNB1,MEPCE,BEND5,MEF2C,CBFB,CD28,VGLL4,ERLIN1,APLN,MOV10,SNIP1,CDK1,OSR2,RPS6KA4,MIR194-1,INPP5K,APOBEC3D,CD83,MIR190B,MIR105-2,H2AC13,MAGED2,CDK5R1,EED,NFIL3,TGIF2,SMAD5,MIR557,DLX1,WWP2,HNRNPA1,MIR216B,ITM2A,MIR106B,TDRD7,MIR490,APOBEC3G,MIR142,DAPK1,MIR556,CREB1,MIR126,MIR553,MYC,MIR184,MIR20A,TADA3,CIRBP,MIR656,TRIM22,PYM1,MAFG,PICALM,ZBTB26,XPO5,MACROH2A1,MIR708,MIR1260B,IRF7,NLRP6,MIR200C,ATP2B4,MIR425,SMAD1,HNRNPC,OAS1,TWIST2,SUMO1,CTBP1,SHC1,ZNF174,DYRK1A,HSBP1,PTPN22,SOX2,GCLC,TRIM37,IRF2,GREM1,MIR940,MIR147B,ZBTB18,MTDH,PROX1,CREBBP,PIWIL2,MIR152,ZNF177,MIR144,TGFB2,CRYBA1,NOTCH2,NCK1,MXD1,ZBTB38,MIR612,RING1,PCNA |
| 4.446e-21 | -46.86 | CUL3 (cullin 3) | protein interactions | 8452 | 2633 | 944 | 19454 | 5460 |
YWHAG,SPON1,CTNNB1,SPATA2,CBL,DDX1,ARMC8,ARL14EP,AK2,WDR82,HSP90AB1,CCT7,HNRNPL,RAB1B,SUMO2,SNRPA1,SNRPD3,H1-3,NCSTN,RPS7,HEXA,SMARCB1,LIMD2,ZNF526,ALKBH4,RPS4X,CBLL1,TFG,RAB18,RUVBL1,ROCK2,BTF3,SNRPB,SLC1A3,CREBBP,HNRNPAB,RPS26,FIS1,COP1,CKB,PRMT5,ZMYM2,SMU1,DLG4,KBTBD6,MATR3,TAGLN2,TAX1BP1,MRPL12,ZC3H14,DDX5,DDX39B,NDUFS2,SRSF2,FXR2,TRA2B,BOLA2B,PHB2,EDC3,RPAIN,AKAP8L,DSTN,METAP1,UBE2N,UBE2G2,ALYREF,CPNE1,SPPL3,ZNF581,AZI2,KBTBD4,COMMD8,ZFP1,CBX3,MAP1B,ZNF451,KLHL24,MEPCE,RPL17,SEPHS1,HNRNPK,SCML1,CFL1,GORASP2,TRIM32,RPL7A,FAM193B,OAT,RBM7,MRPS16,BICD2,UBE2E3,SEC61A1,TRAF7,PSPC1,UQCRC2,CDC20,DAPK1,CD2AP,CDC42,MAFG,SSR1,DDX4,IPP,LSM12,PGK1,DPAGT1,RPL27,TRIM3,PML,RPS15,FTSJ1,BABAM1,VPS4A,DCAF11,DICER1,CETN3,RPLP2,KRT8,RPL8,KLHL7,PRKCQ,PXYLP1,PPIA,DHX15,GABARAPL1,PPP2R1A,RAF1,BUD23,VDR,CSNK1E,ITGB5,SNRPE,GDI2,PCNA,HECTD3,HSPD1,BCKDK,HNRNPA2B1,GTF3C3,COPS4,SACM1L,SMARCE1,PRPF31,HSP90AA1,RMI1,SNRPD2,FAM91A1,ENO2,PRRC2A,PRDX2,ACTB,SIAH1,ACTL6A,TCF19,HEXB,LARP4B,ZFP64,NKAPD1,PYGB,FBXO30,MOV10,GRSF1,LRRC8B,OSBPL8,ZNF688,EIF5A2,ECD,RB1,TES,LDLR,RPL12,HRAS,ACTA2,MRPL24,ZNF7,RPL35A,AURKAIP1,SOX9,NDUFA2,VAC14,DHRS7B,NDUFS3,ACTR2,RPL23A,NKRF,GARRE1,FASTKD5,RIGI,FARSA,NOC4L,RPL26,DHPS,SDF2L1,TRIM27,CTU1,ALB,RPS12,SFXN2,COPE,RPP25L,GABARAPL2,SF3A1,HNRNPH3,RPL26L1,RARS1,CARHSP1,CLK1,RPA3,ZKSCAN1,UQCC3,BRIX1,PIK3R2,PPFIBP1,HSPB1,DRG1,MAGED2,SRSF1,PAIP1,DYNC1I2,TRAF2,RANBP1,SUPT5H,ZRANB2,CRELD1,KLHL12,RHOBTB1,RPL18,SMNDC1,UCK2,RTCB,TRIM11,ACTR1B,FSTL1,CCT8,RWDD4,KRAS,MLF2,BRMS1,COPS7A,RBBP8,TSEN54,FTSJ3,H1-10,SF3B4,TRIM44,ATP5F1B,NEK7,TANK,FDFT1,ADSS2,CTBP1,KBTBD13,EP300,DDIT3,SNRPA,HIRA,MRPS7,EMC1,GPRASP2,COPS5,ZFAND2B,KLHL22,MZT2B,KARS1,RBM17,PGAM1,RPS2,USP15,LANCL2,STT3A,CD274,COQ8A,EEF1B2,CDR2L,COMT,DKC1,TMPO,FMOD,RPS16,MIOS,TWSG1,ZMYM3,RRM1,MRPL47,TMEM165,MRPS18B,RAB13,TRAFD1,SLC25A11,UST,FKBP8,CAPZA1,DYNC1I1,TMEM33,SRPRB,RPS17,EXOC5,PCBD1,ELAVL2,ANAPC4,CALU,DNAJC10,ZFAND6,TRIM23,MRPS28,PSMC5,RPS3,ZBTB33,SUCLG2,SRPK2,KCTD9,BUB3,MRPS21,PPAT,CAPN1,GSTP1,HECTD1,ACACA,CSNK1A1L,RPA2,TCP11L1,ZNF267,EIF2B3,HNRNPH2,BTBD10,SNX11,MARS1,RBM22,TRA2A,EIF3D,WDR11,ZBED4,PRPF19,CLPX,SAV1,TRIM8,KRBOX4,RPL23,UBE2D1,TRAF6,IGBP1,PBDC1,COPS2,THOC2,FOLR1,WDR6,NDUFS8,CETN2,KCTD10,BUD31,GFPT1,NUP153,ASPM,TULP3,TPD52,TXNRD1,GNB1L,RBPJ,GTPBP1,VPS33A,BLOC1S2,ZC3H7A,SLC25A23,DNTT,KLHL25,SRSF4,MCM6,HS2ST1,RFC2,RBBP7,TRIM26,ZBTB14,KCTD17,TRIM37,MCM4,CUL2,EXOC8,SP1,FAM221A,FAS,LMNB1,CDC7,LRRC1,PELO,VGLL4,RAN,CHP1,SNRPB2,GNB1,TNPO3,RPL35,DYNLL1,UMPS,PPP1CB,TIMM13,PRDX3,WDR77,RNF7,ADNP,NUP50,HADHA,THOC3,RTKN,TGFB1I1,SKP1,MLH3,MCMBP,KLHL9,CALR,GMPPA,SSX2IP,PSMD7,EXOC2,SHLD1,PWP2,SRPRA,HACD3,SRP14,SLC25A17,PRNP,DDX39A,EEF1A1,RPL15,TBK1,MTA3,MRPL11,GEMIN7,PPP4C,MRPL49,SNAP23,ZNF787,ARF4,RPS13,PRDX4,MSH6,CTNNBL1,PAK1IP1,CAMK2G,BACH1,PPP1CC,KPNA6,CDC16,PYCR2,WDR45,GANAB,UBE2I,RPS20,UBASH3B,STUB1,EIF4A3,RPL22,LDHA,NR1H2,ARMC6,RBMS2,ELP3,CNP,PSMC4,RPS14,RBFOX2,EEF1E1,CCND1,PDIA2,RPLP0,ZNF574,LMNA,MRPS34,FLCN,EGFL7,PRPF4,MBD3,SS18,POLDIP2,GTF2I,DGCR8,RPL4,SMC4,YWHAH,XPO1,QPCTL,TENM3,INPP4A,DDX50,RPL6,SEC61A2,KCTD20,PEG10,NOB1,RPS10,LYRM2,SUMO3,NUDCD3,TUBA1A,EEF2,TRMT1L,SPC24,DHX38,GCLC,RPS23,DCUN1D5,HGS,TUBB4B,PDHA1,MYO1B,TRIM21,EWSR1,FBXO3,RPL31,FKBP2,HNRNPF,USP30,PSMD1,CPSF2,HNRNPC,LDHB,YAE1,CCT2,CIRBP,H2AZ2,ATG3,MRPL13,VDAC2,CMTR1,POLR2B,CBX5,RPL10,ESR2,QTRT2,EIF4B,SF3B1,GPHN,RAMAC,RPS28,EEF1G,PPIL4,GAPDH,TPM3,ELOC,FAR2,COX5A,KPNA1,TSNAX,RPL24,XXYLT1,MRPS9,SSBP1,RPL32,MYL12A,MALSU1,KCTD3,CAND1,METTL15,STRBP,TP53,RPSA,FURIN,SURF4,ID4,CLPB,DHX9,NEDD8,PDE12,ATP1A2,PSMA5,NUP107,RAB3B,TOR2A,CSE1L,CNNM4,PSMB2,SLC25A1,IGF2BP1,DTL,CDKN2AIP,CSNK2B,PHAX,RNF187,RCBTB1,MACROH2A1,PPP2R5E,DYRK1A,CTSB,IRF2BP1,TXNDC12,GRPEL2,EGLN2,FBXL19,AGO1,LUC7L3,RNF146,TNFAIP1,DDX46,BAP1,NLE1,BCL6,OIP5,HNRNPA1,HMGA1,PIK3R1,PDIA3,NAB2,HNRNPD,HAX1,RB1CC1,MRPS26,SKIC8,ZCCHC9,DROSHA,ATP6V1A,RPL9,MRTO4,STK3,AGK,FAF2,ACTN4,ANP32A,STX12,POLR2C,UCKL1,RPS11,SART3,RPN1,NME1,PRKAG1,BAG2,MRPS11,ZYX,SLC25A5,NEK9,MAEA,THNSL1,RPS27A,SAR1B,ZNF250,CDC123,PYCR1,PMPCA,RPS5,ILK,NLRP3,HTRA2,YWHAZ,SNRPD1,RPS9,TRMT6,THBD,PDLIM3,TUBB,NOTCH2,PGRMC1,IRF2BPL,SLC25A3,ARCN1,KCTD12,BIRC2,TRIM5,TBC1D24,YTHDF1,POR,NLRP1,CHID1,WDCP,KRR1,CWC15,MRPS23,DCUN1D1,DERL2,MRPL50,CD2BP2,MAP2K3,CCT5,MLLT11,KLHL26,CAMK1,ADAMTS1,IFT52,KLHL15,IGF1R,FAF1,SMN1,PTGES3,HUWE1,FN3KRP,BRAP,GMNN,RHOBTB3,PAIP2,GGCX,PPIG,EIF2AK2,ENO1,CTTN,TMOD3,ZBTB17,COQ8B,KLHL28,PPIH,PPM1G,HELLS,DVL2,IDH3A,GID8,PDHB,TBC1D5,GSTM3,UBE2E2,POGK,YWHAB,IKBKB,CORO1C,SPINT2,POLR2L,LANCL1,EIF2S1,FAM98A,TCP1,LYAR,TNPO2,MTA2,KCTD11,PNMA2,RUVBL2,RPAP3,EFNB1,PDIA6,KLHL23,PABPC1,RBM3,RPL28,HNRNPDL,POLDIP3,ZNF609,GTPBP2,DNAJB6,ANAPC2,ZNHIT6,ATP6AP2,KBTBD2,FBXO22,PSMD6,ISCU,KLHL3,NUP62,RPL27A,SUFU,HSPA8,P4HA2,AKAP1,RFC4,XRCC5,RANBP10,RNF41,HNRNPA0,STAU1,CSNK2A1,ACOT8,ZNF24,DNAJB2,RPL10A,TUBG1,BECN1,SNRNP70,LCMT1,SYNCRIP,SDHB,COX4I1,ILVBL,CDC5L,SHPRH,ACTR1A,ZMYM4,IPO8,TNRC6C,CDK4,SELENOF,PSMC3,CHAMP1,NFE2L2,SLC16A1,RPL3,ABCE1,POC1B,NOSIP,MNAT1,KPNA2,RBCK1,TIA1,NCAPG2,MAT2A,TNFAIP3,SUB1,ATP1A1,SPOP,EIF3G,EIF2S2,ZNF655,ZNF330,CSTF3,ROCK1,GMDS,GTF3C4,NTPCR,SPTBN1,SUMO1,UTP15,UBE2M,TRIM36,VPS4B,TRIM68,VIPAS39,ZNF326,FAM53C,RNF113A,PRDX6,BANF1,ZC3H15,HSPA5,KDM1A,PRDX1,PSMD3,DPY30,MRPS35,STOML2,AHSA1,KDM2A,PSMD10,XPO5,RPLP1,HP1BP3,PHB1,NOP58,COPS7B,RPL7,SPTAN1,CCAR2,ATXN10,DCUN1D3,PLD3,RNF126,AP2S1,RPS24,FHL3,NDUFA4,ARB2A,AP1M1,RFC3,EIF2D,PLPP6,LASP1,G3BP1,LAMB2,ETFA,SAMHD1,ZNF668,OTUD7B,RFC5,MCM3,CUL3,KLHL1,PFDN6,MYO6,RPL37A,AP2M1,CPSF1,FAU,EIF3K,MAD2L1,RPL19,RBBP4,RPL7L1,NDUFA5,ZNF805,MYL6,VLDLR,NUBP2,RLIM,ATP5MK,POLA2,PSMC1,G3BP2,UNC45A,TNFSF10,NSFL1C,HDAC6,NFKB1,RNF14,ISYNA1,DNAJC7,EPOP,SLC2A1,ESYT1,NELL2,SEC23A,AIFM1,TRAPPC6B,CAV1,POLR2I,TOP1,EIF2B5,MAP1LC3B,MLLT6,CCDC47,YTHDF2,ILF2,SRP72,ENC1,ZC3H11A,TMX3,HSD17B10,SLC25A10,GLUL,CTNND1,RNF20,EIF3E,SNRPG,HSPE1,ATP5F1A,TUFM,GMPS,NONO,SEC13,XPOT,CCDC22,RTRAF,TRIM24,ACAT1,TECR,TENT2,ZNF507,TXN,RPL13A,P3H1,TIMM23,CDK1,HSP90B1,GPX4,MTDH,SQSTM1,CSTB,FADS2,GABARAP,TMEM209,EIF5B |
| 4.481e-21 | -46.85 | intracellular protein-containing complex | cellular component | GO:0140535 | 909 | 394 | 19108 | 5553 |
MAEA,POLR3GL,USP14,EIF4H,POLD4,KARS1,PSMA4,PSMB4,POP7,HSD17B10,CIAO1,KLHL12,SKP1,DICER1,GID8,RACGAP1,MED31,LAMTOR2,CCDC47,DCUN1D1,POP5,RPP14,DCAF12L2,PFDN2,DDX1,DCLRE1C,EIF4E3,EIF4E2,MAT2B,POLA2,RPP21,TRAPPC2L,EIF4A2,GTF2E1,CTNNBIP1,FEM1A,ACTB,CKS2,GTF2E2,SIAH1,RBCK1,POLR2B,HPS6,CRBN,CCNF,PSMD4,PSMB3,PSMD1,DYRK2,PSMB2,PSMA2,UBE3A,POLR3B,MAD2L2,RTCB,CDC23,DCAF16,KLHL9,XRCC5,DMAP1,ERCC3,CUL2,HSP90AB1,GTF2H5,CAND1,GID4,DCAF4L2,BCL10,RNF144B,CDC20,TRAPPC6B,CBX7,TCP1,PRIM2,DCAF11,STUB1,FBXW4,GTF2F1,DR1,PFDN6,SF3B5,POLR2C,HSPB1,FBXL7,FBXW11,CDK7,EIF4EBP3,RUVBL1,ELMO1,RPAP3,PCMTD1,POLR1B,BORCS6,ADRM1,DTL,OTUD6B,POLR3F,EIF2B3,NAA16,OTULIN,TAF5L,RAP1A,ARMC8,MED10,PRKAB1,AKAP14,SUPT3H,PSME2,TRAF7,PSMC1,UBE2B,FBXO9,RPP25,EIF4B,BLOC1S3,RNF20,BORCS8,PSME1,ELP6,ACTL6A,MED11,UBE2D1,MAVS,TRAF2,MSL2,BAG2,RGP1,FAM8A1,MARS1,FBXL4,POLR1H,AIP,PCGF3,BLOC1S2,RNF40,BCAS4,TADA3,PSMD14,FBXO3,CIAO3,TRIM21,MED21,PSMA3,SCLT1,TOPORS,PRKAG1,PSMG2,OS9,TRAPPC6A,GTF2A1,FEM1C,CCT5,ANAPC16,UBE2L3,NAA11,CCT2,DET1,KIF2A,IGF2BP1,PSMC3,FBXO44,KANSL3,UBE2S,CKS1B,RNF11,TSEN34,CAMK2G,BORCS7,CBLL1,BAG3,SYNCRIP,ENC1,FTL,FBXW7,EEF1E1,PSMB1,CDKN1B,NAA30,PPP3CA,TRAPPC3,PSMA5,JADE1,TMEM183A,CCAR2,KCTD10,NAA35,WDR83OS,DCAF4,NAA15,CNOT8,SUPT7L,CCT7,LAMTOR3,POLD2,GPR37,PSMD12,DCUN1D5,FEM1B,STX12,HSPA8,NFKB1,POLR2F,PSMB9,CSNK2B,TRAPPC3L,YPEL5,UBE2N,FBXO31,ZNF326,EP300,SNAPIN,FBXO7,PSMC4,CTNNB1,CNOT2,BRAP,NCBP2,CCNH,PAAF1,ZFAND2A,MAT2A,FBXO32,FAM98A,PSMB5,PPP5C,PRKRA,ANKIB1,DPM2,PSMD7,SDF2L1,KLHL7,LAMTOR1,KLHL15,CTU1,ENY2,RCHY1,POLR2D,PCGF2,NFKBIA,RTRAF,PSMD3,CNOT6,RARS1,PHC1,CNOT7,TENT2,C9orf72,ELP3,POLR1D,CHRAC1,TADA1,GTF2A2,GTF2F2,SESN3,MCM3,ANAPC4,HSPB8,DHX9,ANAPC2,UBE2V2,CREBBP,FBXL3,GTF2H4,SKIC8,RNF7,CNOT6L,PSMB11,RMND5B,KCTD17,WDR77,APPBP2,CUL3,MKLN1,FBXL19,COP1,FBXL14,CLP1,ING5,EIF4E,WWP2,KLHL22,KXD1,POLR2I,PSMB7,TAF7,CSNK1A1,PSMA1,SNAP25,ASB1,RAG1,PSMD10,RANBP10,TRAPPC4,PGGT1B,BRCA1,MNAT1,POLE4,CDC26,TAF11,KLHL24,DCUN1D3,SESN2,DROSHA,NAA50,TSEN54,PSMB10,RNASEH2C,ACTL6B,PCGF6,UBE2A,TRAPPC1,PSMD6,FZR1,QRSL1,MED17,KLHL3,PSMC5,CDC73,TERT,ACTL9,SPSB3,TSN,UBE2V1,POLE3,FTH1,PRR5L,ANAPC15,FBXO42,TRAPPC14,POLR3H,TCEA1,CDK8,ELOC,WWP1,SLC38A9,POLR2L,TXNL1,RPP25L,VPS72,SYVN1,DCAF5,DGCR8,PAXX,KLHL25,RUVBL2,TAF9,GTF2B,ANAPC11,SPOP,GSK3A,SPSB1,NHEJ1,STK11,PPP3R2,PSMB6,TRAPPC13,PRKACB,TAF10,CCT8,RNF8,SPOPL,FBXO25,CACYBP,PDRG1,BLOC1S5,TAF2,BORCS5,MED30,GTF2H2,FBXO11,TRAPPC10,PSMA6,CSNK2A1,ANAPC13,DCAF8L2,MORF4L1,RAD23B,MED27,UBE2D3,FBXO8,PTGES3,KBTBD6,MEAF6,RING1,TNFAIP1,ZER1,AGO1,SGF29,RASGRP3,TSNAX,ZFAND2B,RNF14,CDC16,POLR2G |
| 4.527e-21 | -46.84 | CDK2 (cyclin dependent kinase 2) | protein interactions | 1017 | 760 | 332 | 19454 | 5460 |
HSPA5,UGP2,NBN,POLD2,PML,RPL27,PRDX6,PGK1,FGFR1,HBB,IDH2,RPA2,GSTP1,UBE2M,HEXIM1,ING5,SPTBN1,AKR7A2,CCNH,RPL10L,EGLN2,DAPK3,BCCIP,CDC20,PSMA6,RPS3,PSMC5,RBM7,UBE2H,OAT,DTL,ELAVL2,ATP1A1,SUB1,CCNB1,VPS39,SMARCA5,ST13,CFL1,RPS17,HNRNPK,CSE1L,KPNA2,PSMA5,NEDD8,MNAT1,IDH1,DHX9,RPL3,CRABP2,ACOT13,BIRC5,CDK4,TP53,RRM1,ATP5PB,APOO,MIF,FZR1,CAND1,RPS16,CDC5L,ALYREF,RPL32,UBE2N,SYNCRIP,SSBP1,CDK6,CEBPG,MCL1,DSTN,H2AC4,TUBG1,RPL10A,RPS2,RBM17,GAPDH,TPM3,CSNK2A1,COPS5,PHB2,EEF1G,SAP18,SPECC1L,XRCC5,RPS28,RFC4,SNRPA,HIRA,DDX39B,DDX5,EP300,CCNI,HSPA8,IL15RA,PIH1D1,CKS2,PAFAH1B1,RPL27A,TCEAL1,TAGLN2,MATR3,ATP5F1B,PSMB6,MIDEAS,LMBR1L,VDAC2,RRAS2,TFDP2,CKB,CCT2,H1-1,SERPINH1,HNRNPC,LDHB,CDKN3,MYC,CREBBP,CASP4,VDAC1,HNRNPF,RPL28,RPS4X,RBM3,CCT8,RPL31,PDIA6,CDK5,TRIM21,MYO1B,TUBB4B,RPL18,RPS23,RPS7,EEF2,H1-3,MITF,TCP1,SUMO2,RPS10,PGR,CCT7,HSP90AB1,S100A8,CORO1C,FKBP4,DDX1,MGMT,RPL6,RAB5C,CTNNB1,YWHAG,YWHAH,PPIB,SMC4,HMGB1,FBXW7,GTF2I,DAD1,RPA3,ARPC2,SQSTM1,HSP90B1,LMNA,CDK1,JUP,TMOD1,RPLP0,TPT1,MYL12B,CCN3,NFYB,CCND1,RPS14,CCNA2,CDK7,SLC25A4,TXN,MAGOHB,TMOD3,LDHA,PNP,RPL22,DEK,EIF4A3,ENO1,CINP,CCNF,OPTN,POLR3H,RPS12,MSN,RPS20,UBE2I,GANAB,MAPRE1,SMAD2,GMNN,TUFM,PPP1CC,RPL26,PTHLH,ATP5F1A,MT1E,HSPE1,POLL,CNOT7,EIF3E,RPS13,ARF4,TCOF1,PPP1R12A,RPL23A,KLF10,ILF2,CCT5,SERPINB9,AURKAIP1,EEF1A1,MAPRE2,TOP1,ARF6,PTP4A3,CITED1,SMAD3,RPL12,TES,SEC23A,RB1,MYBL2,ESYT1,EIF5A2,ATP5MG,FAM133B,CALR,PCED1A,ZMYND11,PAFAH1B2,SKP1,AZGP1,G3BP2,CCND3,POLA2,COIL,HADHA,ATP5PO,MYL6,SLC25A3,MFAP1,PGRMC1,LNX2,ACTL6A,WDR77,H1-5,CDKN1A,RPE,PRDX3,PPP1CB,ACTB,RPL35,PRDX2,CLIC4,ERH,RPL19,ENO2,RAN,CYB5R3,ARF1,S100A6,RPS9,CDC7,SNRPD2,YWHAZ,MYO6,BRCA1,RPS5,SP1,HSP90AA1,DHRS1,RRN3,NFYA,MCM3,MCM4,SAMHD1,CDK20,ATP5F1D,RPS27A,MCM6,UBE2A,ARGLU1,HSPD1,SRSF7,RPS24,PCNA,CTSA,EZH2,SNRPE,SART3,RPS11,CDK5R1,E2F4,FEN1,MARCKSL1,CKS1B,RPL7,SPTAN1,LRWD1,DHX15,RAB11B,CNTROB,EGLN3,PPIA,PHB1,RPL8,RPLP2,PPM1B,CYP11B2,CSTA,RPL23,BCL2L1,CDKN1B,LYZ,DCAF11,HNRNPD,DYRK1B,PDIA3,TAF7,PSMD3,PRDX1,HMGA1,TRA2A,HNRNPA1 |
| 5.088e-21 | -46.73 | TRIM31 (tripartite motif containing 31) | protein interactions | 11074 | 444 | 217 | 19454 | 5460 |
THRAP3,SMN1,RPS13,CTNND1,RPL23A,ILF2,RPL15,TOP1,RPL35A,AIFM1,RPL12,FAM199X,CNN3,H2AC14,MOV10,RPL4,EIF5B,SS18,MAVS,JUP,MRPS34,HNRNPH3,RPLP0,SNRPN,UBA52,RPS14,CNP,RPL13A,MAGOHB,RPL22,UBE2L3,TUBA1B,CTTN,EIF4A3,EIF2AK2,RPS12,RPS20,ALB,TRIM27,RTRAF,NONO,PPP1CC,TUFM,RPL26,ATP5F1A,RBBP7,FLOT1,MRPS17,RPS27A,HNRNPA2B1,NDUFA4,SLC25A5,HSPD1,SRSF7,RPS24,PCNA,SLC39A7,RAB6B,RPN1,SNRPE,GTPBP1,RPS11,ARFGAP1,RPL29,RPL7,DHX15,SRSF10,PHB1,RPL9,RPL8,RPLP2,RPLP1,TRAF6,UBE2D1,DICER1,RPL23,AHSA1,HNRNPD,PRPF19,PRDX1,ZNF207,TRA2A,HNRNPA1,YTHDF1,G3BP2,ATP5PO,SLC25A3,MYL6,PGRMC1,ACTB,RPL35,TUBB,EIF4A2,GNB1,ERH,RPL19,RAN,GNG12,RPS9,SEC61B,SNRPD1,RPL37A,MYO6,LMNB1,NLRP3,RPS5,F2,MCM3,RPS29,HNRNPK,KPNA2,MNAT1,RPL17,DHX9,SLC16A1,RPL3,GNAI3,RPSA,TP53,STRBP,PLG,RPS16,CDC5L,MYL12A,ALYREF,RPL32,SYNCRIP,MRPS9,RAP1B,SNRNP70,RPL24,RPL10A,RPS2,AKAP8L,GAPDH,TMA16,GPRASP2,RPS15,UBE2K,HSPA5,BANF1,RPL27,MAIP1,HNRNPH2,ZNF326,LUC7L3,UBE2W,ZSCAN1,BUB3,PYGM,RPS3,EIF2S2,TRIM23,RC3H2,RBM7,CALU,ATP1A1,IGF2BP1,RPL7A,TIA1,CFL1,RPS17,VDAC1,HNRNPF,HNRNPDL,PRPS1,RPL28,RPS4X,PABPC1,RPL31,RTCB,TRIM21,EWSR1,MYO1B,PTRH2,TUBB4B,RPL18,RPS23,RPS7,EEF2,TRAF2,LYAR,RPS10,FAM98A,HNRNPL,NOB1,EIF2S1,HSP90AB1,SRSF1,PRCC,DRG1,DDX1,UBE2E2,RPL6,PHB2,STAU1,EEF1G,UBE2D3,FXR2,SRSF2,HNRNPA0,TRA2B,SNRPA,DDX5,SF3B1,HSPA8,NUFIP2,RPL27A,SYK,CD59,ATP5F1B,MATR3,RPL10,FTSJ3,RPS26,HNRNPC,HNRNPAB |
| 5.147e-21 | -46.72 | response to organic substance | biological process | GO:0010033 | 2498 | 938 | 18204 | 5365 |
ADCY3,SIN3A,IFI27,ELK1,RRAGB,SERPINB9,CD36,PMAIP1,LDOC1,RERG,SELL,RGS10,RWDD1,GNRHR2,ILDR1,PCK2,JAK1,MYBL2,SYNCRIP,MSX2,AQP4,LILRA2,CXCL3,HADH,CD9,MIR21,YWHAG,CXCL9,FOXP1,IL12B,UBE3A,RNF14,MX2,MIR185,CSK,BGLAP,MIR107,PRL,DMAP1,LDLR,HSPD1,MT1X,VEGFC,SLC1A3,PELI1,PPARA,FLOT1,UPRT,IFNGR1,RXRG,STXBP1,JAK2,BCL2L1,LRP6,TIRAP,BST2,STAT1,ADCY2,CRY1,GSK3A,MIR545,RAMP3,AKR1A1,TUBA1A,ACACA,UGCG,BAD,DERL1,GRIA1,CREBZF,CDC42EP2,GNAI2,IL22,SEC61B,EIF2AK2,CD14,MIR221,PLAA,MSN,NCOA5,CRKL,SLC8A1,TRIM24,PDCD10,RFC3,RNF103,EP300,PIK3R3,MIR95,NPR2,SLC1A2,HYAL2,CTSK,CTNNB1,SLC1A1,GPX1,CCL24,GPT,UBE2G2,P2RY4,TBC1D4,DRD3,UBXN6,SMAD4,GRB10,TANK,SELENOS,DDI1,NFE2L2,TICAM1,DNAJB4,AKR1C1,AKR1C2,MECP2,LILRA1,SRSF4,MAN1A2,PQBP1,IRF1,NTRK2,IFI16,FBXO44,EIF2B5,ACTR2,SHOC2,TAB2,IFNG,SNX10,RNF121,TACR3,SST,EXT1,PTGES3,MGARP,KCNJ11,SMARCA5,GNG2,SERPINH1,DAG1,SRC,ADRA1A,SH3BP4,CALY,TFPI,FIBIN,PHB2,LEP,TRIM21,EPS8,ATF4,HCLS1,FOS,CHI3L1,PML,RPAP2,WBP1L,NFKB1,KCNJ8,IL15RA,B3GNT2,EIF2S1,GNA11,MRAS,CCL4L1,LAMTOR1,CD38,CD2AP,THBD,TICAM2,TLR10,TRAF6,CCL19,PACRG,MT2A,GRM2,TRIB1,ACAT1,SARM1,SLC7A11,PLP2,STC1,SMAD3,EIF4A3,RAP1A,PLSCR4,WNT2,HNRNPD,COL1A2,CRHBP,TAF9,TFRC,CLTRN,GNB1,CLU,CCL23,RPL3,RALB,WDR83,FCGR2B,DNAJC4,NKX3-1,NFKBIL1,ATF3,STAP1,ADIPOR1,SOCS3,CAV1,IFNB1,ACHE,USP8,RBFOX2,HTR1A,GPBAR1,HSP90AB1,ZYX,CDKN2D,FKBP1B,ERLIN1,MSTN,CAV3,MEF2C,SLPI,GFI1,GABRB2,IFIH1,BRCA1,MIR31,TAF2,SMAD2,MIR342,MIR421,MIR324,CLDN1,IDE,ATP1A3,EGR2,ARL6IP5,GPR22,PSEN1,LILRB4,DTYMK,CD4,GSTM3,MIR106B,SOS2,GLRA1,TXNDC17,CREB1,TUBA1B,LY6H,PRDX3,HSPB1,ZFAND6,MIR142,HSPB2,DAPK1,FAF2,IFNAR1,GPR17,CD83,CYP26A1,CDK1,RPS6KA4,KLF9,HTR2A,INPP5K,SRM,NFIL3,HSP90AA1,SMAD5,CHRM5,CDK5R1,IRF7,EDEM1,LCN8,MIR200C,ATP2B4,SMAD1,CHRM1,CAV2,ACTN4,PRKCB,SHC1,FOSL2,LTA,RNF126,RAP1B,OAS1,TWIST2,CRHR1,IDH1,CCL21,MIR20A,TADA3,GPX4,CTNNA1,HSPE1,ATP1A2,LITAF,SLC6A3,POLB,CRIP1,PLSCR3,TGFB2,IL1A,ATP5F1B,PCNA,TWNK,FGF10,IL2RG,PTPN22,NFKBIB,GCLC,FMO1,GSTM2,DDIT4,CDH13,FOLR2,VPS4B,MTDH,CCL20,ADTRP,TNFSF18,SLC6A4,PTGDS,EPO,NR4A2,MKKS,GAPDH,CHCHD4,EGR1,IKBKB,MYRF,IL34,NCSTN,NFYB,MIRLET7G,EDEM3,ESR2,CHRNA7,EZH2,IL3,CHRNB2,IL7,GAB1,BTG2,TSPO,UFD1,PGR,JUP,SESN2,PPARG,CYP7A1,LIPA,SP1,SFRP4,RPL23,CCNA2,PTGER4,CXCL8,TAF7,LPAR1,RRAGA,HADHA,CTSC,IDO1,GPR173,CLEC7A,AZI2,ITGA6,IL13,MIR34A,PRDX2,COMT,P2RY1,TSHR,ADORA1,PTPN11,CCL8,MICB,CCL11,TOMM70,DDIT3,CDK6,INPPL1,VAMP2,TNFRSF14,CXCL10,SPHK2,CYC1,HSP90B1,GLRA2,GPX3,TRA2B,ADNP,OGG1,CGAS,PRKCA,NEFL,CFTR,RAD23B,XAF1,RPS16,EDEM2,CCR2,CACYBP,SLC29A1,INA,FBXO3,PSMD14,HSPB8,PLSCR1,ADIPOQ,ZC3H15,RBBP7,CCR3,H2AZ1,IL10,ROCK2,PTGFR,SRSF2,RAF1,DBH,PAQR8,CX3CR1,MIR145,TRAF2,HRH3,TRAF1,PPP1R1B,RPS3,LY96,TRIM6,MME,HMGB1,GABRB3,CXCR1,PTK7,RGS2,RDH11,CAB39,CXCR4,AGER,HRAS,PYCARD,RIGI,PAX6,SMYD3,ADSS2,WNT10B,TXNIP,EDNRA,MIR204,CDC42EP4,CD80,OPTN,GUCD1,UCN,TUFM,CIB2,IFNK,PLCB1,TLR9,TNFRSF1B,MTAP,MCL1,MGST2,SELENON,HM13,FABP4,DNAJC3,MIR96,DNAJB2,IFNA2,JKAMP,TNIK,PSMB2,CDC73,MIR223,ACVR1C,SLC2A8,GNRH1,DNTT,MMP14,ERLIN2,FCER1G,DDX1,UBE2K,IL6,AHCYL1,CHRM4,TP53INP1,MIR379,EIF4E,BAX,TRAF3IP2,UQCRC1,ADIPOR2,PADI2,GNAO1,MMP9,CD86,GNAQ,IFNA10,PTP4A3,AKT2,VPS26B,ERRFI1,CA2,MX1,FOXP3,CD274,HAX1,OXSR1,PRNP,DAPK3,PHC1,PPP5C,MIR187,PCSK9,NR1H2,USP46,ACP5,PRKCE,EGLN2,CDK5RAP3,SYVN1,ATF1,DIO2,KRT8,MIR320A,EIF4A2,TOLLIP,RPL27,RPL13A,XBP1,KIT,PID1,FAS,PAK2,TRIM63,IL2,TGFBR2,CCND1,CNR1,SOD1,AR,UBE2W,RFTN2,UCP2,IGF1,NFKBIA,NSG1,CALR,AGTRAP,BAK1,VDR,MAP1B,GSTP1,GH1,TNFAIP3,OXTR,RETN,MT3,CXCL11,CREB3L4,SLC6A1,WNT7A,PPP3CA,FAM107A,KBTBD2,CEBPE,ELAVL4,MIR182,IL1B,TGFB3,ESD,AKT1,AIFM1,TLR6,RTF2,IFNA13,ITGA2,FKRP,PFKFB2,IL15,ABHD2,TLR1,NSMCE3,PDE1B,ALPL,MIR455,FGF23,TIMP1,LAMTOR2,KLF1,CUL3,PIK3R2,CCDC47,NR2E1,RAN,PIK3R1,AMIGO1,OSM,CCL1,FZD4,CAPN2,OPRK1,RXFP2,MIR493,IL17F,PIK3CA,TIAM1,CD47,F7,ICAM1,GPIHBP1,PDCD4,ROCK1,P2RY12,MIR143,MIR15A,GNPAT,CAMP,IL18,CSH1,KLF3,LAMTOR3,CD58,BACE1,INSIG2,FASLG,MIR140,PDE4B,PIK3CG,REG1B,DUSP6,CCL2,SYP,MAP2K6,NPPC,IL2RA,NHERF1,RPL10A,PDE2A,WBP2,CACNB4,MIR16-1,CHRM3,PIGA,DRD1,OPRL1,GPR75,HBE1,SLC12A2,CYP1B1,FKBP4,TLR2,G6PD,RARRES2,VAMP3,P2RY11,VPS54,STAT5A,CDK4,NPTX1,CYRIB,TBK1,XRCC5,LHB,SLC2A1,MIR101-1,ASIC1,GLUL,TRIM32,UBE2L3,GPAM,YES1,BIRC2,DUSP1,SLC23A2,LAMP3,KBTBD6,NLRP1,CCR4,CH25H,SYK,TMBIM6,CD40,DERL2,TESC,S100A8,HDAC6,SELENOT,STK11,CREB3,EEF1E1,MAVS,CMA1,STAMBPL1,EFNA5,RUVBL2,GPR35,SOCS5,IL20RB,HSPA5,HTRA2,IL4,TACR1,MYD88,CCDC186,AQP3,EPHX1,MIR149,MIR146A,CD81,CCL5,RGS19,KCNB1,RORB,KCNC1,PELP1,EPHA4,TLR3,MIR200A,DEFB124,IL2RB,AKAP12,IGF1R,SFRP1,CCL17,TIMP3,PTGER2,FBXO32,CRYAB,SOCS2,CDC42,ATP5F1A,CCL3,HNF1B,YWHAH,CNTFR,LILRB1,BCL10,REN,IL12A,IRF3,STX8,CSF2,IL6ST,SETD7,OPRM1,TLR7,EIF4EBP2,SLC38A9,OR51E2,IL5,CTSB,KDM1A,DHX15,OS9,GAD2,MRC1,HDAC5,CCR1,IRF8,GNA14,SYNGR1,IGFBP4,REG1A,GHRL,CPEB1,HNRNPA0,IL1R2,SOX9,STAT2,CBL,BAG3,ERO1A,CCR5,BECN1,UBXN10,IGBP1,RAB13,DNAJB9,CYP1A1,BRINP3,TMUB2,KLHL15,MAP2K3,MIR370,GABRG2,AANAT,SESN3,GJB2,JAGN1,IL18BP,LIAS,KCNMB1,EIF2B3,CXCR6,COL3A1,RMI1,SPP1,GLRX2,DKK1,SDF2L1,DHX9,ISG15,STAT6,CCR7,MAT2A,FAM8A1,CCR6,SRSF7,HCFC2,ADRB2,HAND2,CST11,MBD3,CXCL1,SULT1A3,RNF139,TRIM44,CYP27B1,B2M,FAF1,SLC22A6,EIF2B2,CDKN1B,CDO1,HELLS,NQO1,MLC1,KLHL22,IRAK4,CHMP5,CXCL13,UFL1,SLC16A1,SGTA,RPL15,MDM2,TNFSF10,BRINP1,ST6GAL1,TP53,HTR5A,GNAI3,SOST,HPCA,POR,CNP,LEPR,SOD2,DDX5,UGT1A1,TIMP4,TMEM38B,TRIP4,ACKR3,GABBR1,TRAM1,HSPA8,PTPN1,LARGE1,BRINP2,LILRA3,GHR,TOR1B,KLF4,ZBED3,HOMER1,TLR4,FOLR1,CDKN1A,LRAT,TMSB4X,CDK9,MIR105-1,GPR83,RAB31,CASP4,CCL18,PTGER1,ILK,CITED1,NUP35,RB1,GREM2,SLC25A5,MRGPRX1,TYMS,CYP11B1,SLC22A12,MIR17,GJA1,CXCR3,NLRP3,CCL25,CASTOR2,AIF1,FOXC2,TIFA,CLDN3,MAPKAPK3,PDCD1LG2,CSNK2B,TNF,VAPB,SHMT1,CYP11B2,ACTB,MUL1,XCL1,TMUB1,CX3CL1,ATP1A1,RDH12,AVPR1B,ERLEC1,PHB1,EDA2R,PDIA3,PDE12,STUB1,DNAJC10,TOP2B,CDK5,KCNMA1,CXCL12,RAB11B,CLDN4,FBP1,RNF5,MIR98,DUSP10,IL1RAP |
| 5.684e-21 | -46.62 | RPS3A (ribosomal protein S3A) | protein interactions | 6189 | 593 | 272 | 19454 | 5460 |
PPP1R12A,FAF1,RPL23A,PC,HUWE1,THRAP3,NOC4L,VRK1,RPS13,EIF3E,FBP1,MAP2K3,AURKAIP1,EEF1A1,RPL15,TNFAIP8L1,LLPH,ILF2,SOD2,SRP72,EFNA3,RPL12,KRR1,ARL10,RCHY1,PRR3,LDLR,DCUN1D1,RPL35A,CDK9,NOP9,HDAC6,CRBN,RPA3,SIRT7,NPM3,NF2,HMGB1,RPL4,FBXW7,PIAS1,UTP23,AATF,RPS14,CDK7,LMNA,JUP,METTL14,GRM2,RPL26L1,RPLP0,CCNF,METAP2,TUBA1B,EIF2AK2,PRKRA,GSK3A,RPS12,RPS20,UBE2I,NDN,SLC25A4,RPL13A,RPL22,CREB3,RPL26,FBXO7,PPP1CC,DNAJC8,SLC25A5,PPAN,HNRNPA2B1,RPS24,G3BP1,TRIM26,TRIM37,RPS27A,RAD21,B3GNT2,ACTN4,RPL29,MAK16,EZH2,CHMP4C,NGB,RPS11,SART3,RPL9,FOLR1,RPL8,PHB1,COPS2,RPLP2,RPLP1,NOP58,RPL7,HNRNPA1,ZCCHC9,RB1CC1,AHSA1,HNRNPD,RPL23,NMRAL1,CCDC86,NOP53,G3BP2,WDR77,H1-5,APOBEC3C,LARP4B,EMC9,ZNF22,RPL37A,SEC61B,RPS9,MRPL23,ACTB,RPL7L1,RBBP4,RPL35,MAD2L1,TNPO3,MAD2L2,RPL19,CUL2,CUL3,ZNF668,RPS29,ZCRB1,BRCA1,RPS5,HSP90AA1,RIT1,MRPL52,SNIP1,ABCE1,RPL3,DHX9,NEDD8,TGFBR2,MEPCE,PDRG1,EDEM2,RPL17,UBL4A,TP53,RPSA,H2AX,ACTR1A,TFCP2,DNAJC2,RBM34,RNF8,SYNCRIP,RPL32,ARL4D,FZR1,RPS16,CAND1,RPS27L,RBM42,TMPO,SURF6,ENY2,CD81,COPS5,CSNK2A1,GAPDH,API5,E4F1,TUBG1,RPL24,SNRNP70,RPS2,NOL12,USP15,RPL10A,BAP1,RPL27,RNF113A,RPS15,HSPA5,SPTBN1,CFTR,FGF13,RPA2,SSR1,UBE2M,HEXIM1,KLF4,ZNF770,RPS3,PSPC1,PHAX,RPL10L,SMURF1,SRPK2,SMARCA5,RPF2,MAT2A,RPL7A,RPS17,SPOP,RC3H2,ZBTB38,UBE2H,RPL31,PABPC1,H1-6,KRAS,RUVBL1,RPL28,RPS4X,MED9,TUBA1A,SOX2,RPS7,EEF2,GLE1,TUBB4B,MTA2,HGS,CSTPP1,RPL18,RPS23,MPDU1,RPS10,HNRNPL,LYAR,HSP90AB1,IFI16,WWP2,RPL6,XPO1,NGDN,DDRGK1,CTNNB1,DRG1,DDX39B,PYM1,RPS28,HDAC5,HSPA8,DDIT3,YAF2,EIF1B,UFL1,STAU1,SAP18,RPL27A,MTF1,FBXO42,EIF4B,PIH1D1,VDAC2,ATP5F1B,MATR3,RPL10,MYC,HNRNPC,SFN,HNRNPAB,THAP7,RPL39,BTF3,ATG3,PSMD14,FTSJ3,ICAM1,RPS26,NSA2,H1-1 |
| 1.037e-20 | -46.01 | negative regulation of biosynthetic process | biological process | GO:0009890 | 2690 | 999 | 18204 | 5365 |
ELK3,KLF3,CCDC85B,MIR572,MIR891B,H1-3,INSIG2,FASLG,HNRNPA2B1,MIR140,MIR939,EID1,CBX7,APEX1,PIK3CA,MIR143,ETV6,MAGOHB,MIR15A,STAU1,SUPT4H1,PDCD4,MIR139,MIR30E,YWHAZ,MAGED4B,FOXP2,MIR301B,MIR922,NR0B1,CUL3,MIR24-2,RAN,MIR944,NR2E1,MIR493,CRYM,NIBAN2,H2AJ,SOX14,MIR218-1,ELK4,MIR532,PPM1B,NUDT16,MIR298,MIR455,MIR194-2,EIF3E,MIR137,MIR769,NSMCE3,MIR874,CCAR1,SATB1,VEGFA,MIR652,IL23A,MTA2,TMBIM6,HNRNPL,ACVR1B,NR1I3,MIR592,MALSU1,MIR129-2,CCAR2,ALKBH4,APOBEC3C,MIR208B,NOG,HDAC6,SGF29,MIR616,FBXW7,MAGEB1,MIR101-1,MIR363,VSIR,NIF3L1,RASD1,CNOT6L,ASB1,MAGEA4,TNRC6C,RPS13,MIR183,H2AC1,GCHFR,MIR373,MRPL13,C1D,APOBEC3A,MIR32,MIR632,ZBTB39,TBK1,XRCC5,PIAS1,PDE2A,CIART,RBM42,POU1F1,MIR7-1,MRTO4,H2AC25,PSMC5,NPPC,IGF2BP1,MIR16-1,MIR1224,HMX1,CD274,FOXP3,COPS2,PPP2CB,KLHL25,DAPK3,SMARCE1,MIR607,MIR589,LMNB1,MIR130B,PRNP,ERLIN2,NKX3-2,MIR223,MACIR,MAGEC2,SOX21,CHMP1A,PYDC2,LSM5,BAHD1,IL6,ID4,TP53INP1,EIF4E,MIR379,ZBTB2,RPL10,MIR580,MIR383,ZBTB16,SMG8,ZNF24,MIR148A,E2F6,HDAC3,MIRLET7D,MIR196B,PLCB1,ORMDL1,KCNIP3,FABP4,MIR648,IFNA2,MIR96,CDC73,SFN,DNAJB6,NACC2,TXNIP,WNT10B,NMI,FOXS1,ZBTB33,MIR423,MIR577,MIR204,PAX6,MAD2L2,MIR454,MIR887,ANXA4,UCN,TGFB3,SIAH2,AKT1,MIR569,PPP3CA,CLP1,MIR374A,MIR182,MIR211,MIR595,EXOSC8,TLR6,DUSP26,CALR,MIR639,SIRT7,SKIC8,MIR331,MIR675,TCF23,CNOT2,PPP1R11,SAP30,MIR604,IGF1,PTRH2,MIR345,CCND3,MIR877,MXI1,INPP5E,VDR,TXN,BAK1,MAX,GSTP1,RBBP4,TNFAIP3,PID1,MIR631,MIR320A,MIR1251,RPL13A,MIR492,SOD1,AR,UBE2D1,MIR130A,MIRLET7B,PHF1,PAIP2,CCND1,HIRA,MIR187,MIR125A,NR1H2,ACP5,PHC1,TSG101,E4F1,TCEAL1,MIR10B,MIR448,MIR450B,HSPA8,PCGF2,MIR26B,SAP18,CNOT8,MIR99B,TLR4,APLNR,MIR147A,PAX9,TGIF2LX,KLF4,TP53,MIR583,MAEL,MIR671,MDM2,MIR188,SDCBP,HENMT1,PCGF6,ZC3H7A,LEPR,NCBP2,DDX5,MIR1-1,HOMER3,SUFU,SUV39H1,MIR193B,MIR218-2,CDKN1B,IMPACT,HELLS,KLHL22,APOBEC3H,MIR503,MIR212,RBM15B,ZBTB14,CYP27B1,MIR638,ZNF668,ZNF692,RNF139,MIR335,MIR198,DROSHA,MIR1249,LHX2,IFRD2,RPS26,MIR195,PIWIL1,HEXIM2,CDK5,BCL6,PFDN5,HFE,MIR615,HMG20A,ORMDL3,MIR628,PKIA,ITGB8,HINFP,MIR649,FBP1,MIR1296,MIR98,KDM2A,EMILIN1,NAB2,MUL1,XCL1,RBPJ,CX3CL1,MIR1298,BRMS1L,SHMT1,TNF,MIR9-2,TWSG1,HMGA1,PHB1,ING1,PDE12,ATP1A1,MIR191,MIR624,PAIP2B,MIR764,NLRP3,MIR502,H2AB1,MIR17,MIR214,PPM1D,ZHX3,GJA1,MIR552,PDCD1LG2,FOXC2,H1-5,CASC3,CLDN3,MDFI,CDKN1A,MIR16-2,SDR16C5,NDN,MIR105-1,LSM14A,SUPT5H,RIOX2,RB1,MIR301A,CITED1,TYMS,NAB1,EID2,PHF12,MIR338,LILRB1,MIR132,IL12A,MIF,HNF1B,CCL3,ID1,MIR1225,KLF12,SRSF12,IRF3,BARX2,HEY2,CSF2,BTN2A2,MIR942,MIR3173,MIR7-2,MIR200A,EPHA4,MIR605,RPS14,MOSPD1,RORB,AGO1,CRYAB,MIR302B,SFRP1,FLCN,MAGEH1,MIR484,MIR761,NPTN,MIR504,IL4,MIR662,IL20RB,SOCS5,THAP1,BEND6,MIR146A,NKRF,DGCR8,SCML1,CD46,MIR149,FURIN,MIR760,ZBTB17,TYROBP,MIR661,CPTP,MIR876,MIR101-2,CHID1,ING2,RUVBL2,DKK3,MIR150,LANCL2,MIR452,MIR25,MIR367,DHX9,DKK1,MIR600,MIR30D,MIR517B,DDX4,ZNF345,HCFC2,SRSF7,MIR1226,MBD3,HAND2,BHLHE40,STAT6,THAP7,RNF8,CCR7,MIR192,MIR597,LRP3,MIR370,RLIM,MIR346,MIR449B,OTUD7B,LSM2,MIR9-1,TLE1,RERE,SOX9,NDFIP1,MIR429,GHRL,MIR551B,RGN,CSNK2A1,EXOSC4,CPEB1,DHRS7B,IL1R2,CNOT6,IGBP1,DCAF5,DLG1,MIR215,BANF1,IKZF5,DICER1,MIR489,ZCCHC7,SNAI2,NR1I2,KDM1A,PELO,TRIM29,MIR339,MIR29C,EIF4EBP2,TSN,CD200R1,MIR558,MIR488,CCR1,HDAC5,MIR511,IRF8,PRMT2,TOB2,SAP30L,MIR936,SMARCA5,PPID,ANGPT1,PIWIL3,MIR34C,SRC,SRGN,NRDE2,MIR765,POLR2G,LEP,HNRNPK,SQSTM1,CD200,MIR601,ATF4,HEXIM1,MIR148B,ZNF175,PHB2,MIR7-3,IFNG,MIR873,ZBTB5,DYNLL1,TENT2,MIR34B,BIRC5,LGR4,MIR135B,PRKRA,MEF2A,HOXB8,INSM2,IRF1,ITM2B,BRMS1,TRIM3,MIR100,MIR625,GTF2IRD1,EIF4EBP3,MIR153-1,TCEAL7,METTL14,CTNNBIP1,MIR618,MIR563,MIR551A,CCDC3,MYT1L,TLR8,CIPC,MIR296,IFI16,MIRLET7I,MECP2,MIR181C,BMPR1A,DNAJB4,SOX3,PRMT6,SRSF4,EXOSC3,MIR542,EDC3,MIR29A,DRAP1,MIR549A,KLF10,PCGF3,MACROH2A2,MIR599,MIR924,SETD5,MIR23B,MIR205,MIR653,FCGR2B,NKX3-1,ATF3,NFKBIL1,DUSP22,MIR24-1,SMAD3,MAGEB10,SCML2,NR2F6,IRF2BP1,ELOC,SERPINB1,EIF4A3,MIR920,PNRC1,HNRNPD,TUSC2,MIR222,ZBTB25,GADD45A,TRAF6,MIR802,CD2AP,CD38,NUDT12,MIR1180,MIR181D,PLAGL1,MIR378A,SFTPD,H2AZ2,PML,HCLS1,PSPC1,IRF2BPL,PABPC1,MIR937,NFKB1,MIR141,LRIF1,MIR491,TERT,SNAI3,EIF2S1,ARG2,CBX3,DMAP1,MIR885,ENO1,LDLR,JUN,MORC2,MIR186,PPARA,MIR449A,ZNF263,MIR10A,MTA3,IL12B,MIR185,LDB2,PCBP4,MIR190A,FOXP1,THRAP3,MIR107,MIR1-2,MIR633,CSK,RFX5,ERP29,USP2,RGCC,TIA1,SYNCRIP,MIR330,MIR548C,ABCC2,MIR651,MIR519D,MIR30B,MIR21,INHA,MSX2,WDR82,ANAPC2,MIR375,CPNE1,SIN3A,IFI27,LYAR,PC,FOXD3,MIR197,TCF21,DXO,POU5F1,MIR33B,SRSF10,MIR129-1,CD36,MIR593,BAP1,MIR210,MIR938,MIR136,NOP53,GMNN,MIR578,ZMYND11,LMNA,MIR1271,EID2B,MIR9-3,SELENOS,SMAD4,MIR92B,H2AC6,MIR99A,LSM4,PRMT5,RNF128,OVOL1,PDCD10,MAGOH,EP300,DR1,MIR384,H2AC7,TSNAX,ANXA7,MIR1227,BACH1,CTNNB1,SP2,MIR643,H2AC4,EIF2AK2,MIR206,SNX12,LMO4,CREBZF,MIR377,AATF,NCOA5,CRKL,MIR497,TRIM24,MIR221,MIR155,PHF21A,MIR573,BST2,USP3,STAT1,MCPH1,MAF1,MIR500A,DEDD,CD34,SMCHD1,DEFB114,CRY1,GSK3A,MIR155HG,SIX5,PIWIL4,HELT,FGFR1,MIR340,ATXN1L,NKAP,DDIT3,TRIM27,POLE3,CDK6,DNAJC2,NONO,MIR586,MIR590,PTPN11,ENC1,SMG9,IDO1,TAF7,CXCL8,MIR133B,IL13,MIR609,UBE2D3,MIR34A,MIR216A,ZNF451,CYGB,VPS72,MITF,MIR770,PGR,MIR711,GPNMB,SLA2,MIR106A,SESN2,MIR193A,DCP2,UFD1,BTG2,TSPO,ZBTB6,RPL23,MIR30A,PTGER4,MIR626,PPARG,MIDEAS,CYP7A1,MKKS,CNOT7,MIR422A,EGR1,MIR934,GAPDH,EPO,MIR28,NR4A2,LSM6,RAD21,MIR554,CHRNA7,UPF3B,EZH2,MIR1262,EZH1,MIRLET7G,YTHDF2,ESR2,RGS2,EPHA2,CXXC5,MIR495,HMGB1,AGER,MIR23A,PYCARD,HRAS,MIR361,ZNF304,GABPA,MIR875,ROCK2,IL10,FERD3L,MIR640,YAF2,MIR567,H2AZ1,MIR611,STN1,SRSF2,ADIPOQ,RBBP7,LBH,MIR505,MIR636,DDRGK1,TRIM6,RPS3,FOXP4,ETF1,MSX1,CBX5,CX3CR1,MIR145,NMBR,NKX6-2,TAGLN3,LDB1,XAF1,EIF4E2,TFDP2,DIS3L,MIR581,MIR1277,ACOT8,MIR657,MIRLET7C,F2,CGGBP1,APOBEC3B,INPPL1,PSMD10,ADNP,MIR424,DAP,H2AX,ZBTB45,SPINDOC,FBXW11,CDK1,MOV10,SNIP1,APLN,RPS6KA4,MIR194-1,OSR2,INPP5K,APOBEC3D,MIR190B,CD83,MIR105-2,H2AC13,MAGED2,CDK5R1,EED,TGIF2,NFIL3,MIR557,SMAD5,MIR216B,HNRNPA1,DLX1,WWP2,ITM2A,MIR106B,MIR490,TDRD7,MIR142,APOBEC3G,MIR556,DAPK1,MIR553,MIR126,CREB1,MYC,MIR184,BRCA1,MIR31,WWP1,SMAD2,MIR342,RUNX1,ZMPSTE24,ZMYM2,GFI1,PKIG,MIR208A,PSEN1,ARB2A,LILRB4,ZBTB42,AP2A1,HBEGF,MIR324,ZHX1,ZGLP1,APOBEC3F,UBE2I,RC3H2,RBFOX2,SMG5,RBBP8,IFNB1,TRIM11,CAV1,MEPCE,BEND5,MEF2C,CBFB,CD28,VGLL4,ERLIN1,DYRK1A,HSBP1,PTPN22,SOX2,TRIM37,GCLC,IRF2,ZBTB18,GREM1,MIR147B,MIR940,MTDH,CREBBP,PROX1,PIWIL2,MIR152,ZNF177,MIR144,TGFB2,CRYBA1,NOTCH2,MXD1,NCK1,ZBTB38,MIR612,PCNA,RING1,MIR20A,CIRBP,TADA3,MIR656,TRIM22,PYM1,PICALM,MAFG,XPO5,ZBTB26,MIR708,MACROH2A1,MIR1260B,NLRP6,IRF7,MIR425,ATP2B4,MIR200C,SMAD1,HNRNPC,TWIST2,OAS1,SUMO1,CTBP1,SHC1,ZNF174 |
| 1.053e-20 | -46.00 | mitochondrial envelope | cellular component | GO:0005740 | 798 | 353 | 19108 | 5553 |
PMAIP1,MRPL51,COX6B2,MRPS9,GPAM,MRPL57,STARD13,MFN1,AK2,GNPAT,PLA2G4B,TOMM40,UQCC2,COX16,PTPMT1,MGARP,NDUFB10,CRAT,PMPCA,MRPS23,TWNK,MTG2,COX4I1,PLAAT3,UBIAD1,ATP5MG,BAK1,TUFM,ATP5MC3,MUL1,MTARC2,SLC25A5,CNR1,ELK1,PHB2,MRPL16,MRPS18C,COX6C,ARMCX1,LDHB,RSAD2,ATP5MK,NDUFA12,STAR,MRPS18A,MPC1,SLC25A10,UQCRC1,ATP5F1A,IFI27,TSPO,COX11,SLC39A9,UBA52,CMC4,HSPD1,MAIP1,MRPL33,RAB32,CYP11B2,GRPEL1,UQCC3,PNPLA8,LGALS3,MRPL17,NDUFA1,FGR,MTCH2,MIEF1,SFXN1,TIMM13,SLC41A3,AURKAIP1,SLC25A20,CHCHD6,RPS3,NDUFB8,TMEM70,REXO2,NDUFS8,RNF144B,SLC25A46,TIMMDC1,VAMP1,CLU,TIMM8B,COA4,TMEM160,ATP5MC1,COX20,BOK,MRPS18B,HSD17B8,BCL2A1,TOMM40L,MRPL22,CYB5R3,TIMM29,EPHA4,VDAC2,COA1,MRPS21,GK2,MRPL11,UQCC6,ATP5PD,AKAP1,AIFM1,NDUFB7,UQCRH,MTG1,MRPS33,MTHFD2L,NDUFC2,SLC25A11,SH3GLB1,MRPL34,STARD7,MRPS28,TMEM14B,COX7B,NDUFA5,MRPS25,COX7A1,NDUFAF4,PTPN1,NOA1,PLSCR3,COX19,FKBP8,MRPL13,NDUFAF6,BNIP3L,PGS1,MAVS,FATE1,ATP5PB,EFHD1,IFI6,FBXL4,NME4,SARM1,DNAJC19,CARD19,TRMT10B,TOMM70,MRPL18,RNF5,SFXN2,NGRN,CYP1A1,COX14,TIMM17A,COX5A,QTRT2,CCDC90B,MRPL47,MRPS17,NDUFA2,MT3,MRPS7,PSEN1,PPP1CC,CYC1,NDUFV2,MRPL36,CYP11B1,SLC25A4,ATP5F1E,ABHD6,MRPL53,ARMC1,UQCRC2,CHCHD1,TMEM126B,SMDT1,SDHB,COQ10B,SLC25A32,NDUFAB1,GPD2,TIMM21,SDHC,DELE1,PHB1,FAM162A,FUNDC2,PRELID1,TOMM7,NDUFS6,ATP5F1B,MRPL24,MPV17,PGRMC1,STOML2,ATG9A,GHITM,MCL1,HTRA2,CHCHD3,TOMM22,SLC25A28,FIS1,CPT2,ARL2BP,SORD,ARMCX2,AGK,SPHK2,GRPEL2,MRPL41,SYNJ2BP,TMEM126A,DUSP18,PDSS2,ACSL4,THG1L,RAC2,COX8A,MRPL9,SLC25A44,COX6A2,SRC,DCAKD,FUNDC1,SLC25A12,TIMM23,DUSP21,NDUFA4,NDUFS2,TMEM11,TRAF3IP3,PTRH2,AGPAT5,MRPL50,BAX,ADCK1,HADHA,MRPL20,HINT2,EXD2,UCP2,CHCHD2,TAMM41,TMX2,BAD,ALPL,MRPL12,NRP1,MRPL49,CYP27A1,APOO,COQ8B,ATP5F1D,COX10,COX17,MRPS34,SLC25A42,SLC25A27,KRAS,DNAJC30,NDUFS3,COX6B1,CIBAR1,HAX1,ARMCX3,MRPS35,CYB5A,MRPL10,CISD1,NDUFAF3,SLC25A24,UQCRQ,TMBIM6,SLC25A23,TYMS,CHCHD4,ATAD1,RNASET2,SLC25A51,USP30,PRKCA,CYB5B,COX7B2,SNN,VDAC1,CYP27B1,SLC25A3,ZDHHC8,UFL1,ATP5PF,KGD4,MRPL23,TAFAZZIN,CNP,SLC25A31,MARCHF5,CHDH,NDUFB6,RMDN3,BCS1L,FKBP10,HIGD2A,SLC25A26,NDUFAF2,CLPB,SAMM50,GABBR1,DMPK,MRPS11,TMEM14A,MRPS26,MAP1LC3B,BECN1,COX4I2,CLPX,PGR,PPIF,MRPL40,PARL,DEGS1,PDE2A,RPS27A,IMMP2L,TOMM6,TIMM8A,MRPS16,RAF1,SLC25A21,MRPL52,ROMO1,SOD1,MPV17L2,UBB,SLC25A45,UQCR11,NDUFB4,MTX2,SMCP,SLC25A39,TIMM10,TMEM177,SLC11A2,NDUFB5,BCL2L1,SLC25A1,ABCG2,TOMM20,ATP5PO,CPT1B,MGST3,PLN,SLC25A14 |
| 1.145e-20 | -45.92 | LMNA (lamin A/C) | protein interactions | 4000 | 1217 | 487 | 19454 | 5460 |
MACROH2A1,B4GALT1,PITPNB,PHAX,SYNGR1,UBA3,VAMP5,SLC25A1,SUGP1,TMEM41A,SMARCA5,SLC35B4,CFL1,PRKACB,MECP2,ALKBH5,PDCD4,PML,ITM2B,NBN,TXNDC17,LRP10,TEX264,DDX46,TMEM243,DERL1,ELOF1,PGK1,BNIP3L,GRPEL1,TRAM1L1,CD2AP,SSR1,KCNK13,LEMD3,LUC7L3,TFIP11,ALYREF,RPRM,SSBP1,ADD1,VTI1B,LMAN1,LCP2,STX6,USP2,DHRS7,GAPDH,PPIL4,CD81,SMCHD1,H2AC4,ADGRE2,AKAP8L,ZDHHC15,KPNA1,PSME1,MAP1B,CYBRD1,HNRNPK,H3C1,NUP107,MEPCE,SMIM11,INSIG2,TP53,ESS2,TMSB10,DISC1,DDX42,RP9,NUPR1,DLST,CMTR1,FAIM,TAGLN2,MATR3,KBTBD6,ALG5,CYB561D2,HNRNPC,MYC,BTF3,PSMD14,CKB,H1-1,MDH1,DDX39B,JAGN1,PCGF2,DDX5,TMEM203,SF3B1,PHB2,GOSR1,TRA2B,BET1,CHST1,SMCO4,CNDP2,CSNK1A1,RAB35,STX5,SUMO2,SNRPD3,HNRNPL,C1QTNF1,ANKRA2,RPL6,SLC38A7,CLEC1A,BAZ1B,CTNNB1,DDRGK1,MARVELD1,DEGS1,CBL,CD52,PEX3,TRIM21,RUVBL1,XPNPEP1,ROCK2,TMEM60,PELI1,DHX38,TRMT1L,SPG21,RPS7,NUP37,DNAJC25,PDHA1,ENO1,EIF2AK2,CTTN,GTF2A1,MGST3,COPE,VIRMA,PDCD5,DEK,SCML2,CNTNAP1,DNAJC8,RACGAP1,HMOX2,FBXO7,CSGALNACT2,ZKSCAN1,RPA3,SOD1,PPM1G,HELLS,RTN4,ENTPD3,CLK1,FBXW7,PIK3R2,YKT6,SLC7A1,PIAS1,SEC22B,RABL3,METTL14,WTAP,LIMS2,CXCL14,SMAD3,PTPN1,RB1,DERL2,AIG1,PMM2,MOV10,KIAA1143,OSBPL8,BRD3,BTN2A2,RAB1A,ERG28,SGMS2,NOC4L,DNAJC30,SELENOK,TRIM6,FBP1,CD2BP2,PDE6D,FAM169A,SEC61B,ZMAT2,SNRPD2,SNRPD1,ACTB,SIAH1,THBD,PDLIM3,ACO2,TM4SF20,BRCA1,YWHAZ,ILK,VMP1,SCFD1,DNAJC3,CFDP1,RABAC1,RADX,CMAS,STX7,AGTRAP,PGRMC1,TOR1AIP2,RFXANK,VAPB,KCTD12,MFAP1,IFIT2,CETN3,MFSD5,TYMS,DHX15,NUP35,PMP22,HNRNPA1,PDAP1,NAB2,MRPS26,HNRNPA2B1,SYPL1,HSPD1,SLC25A5,PCNA,DHX16,TNF,SSRP1,SACM1L,NEU1,GIN1,B3GNT2,CHMP4C,AQP3,GDI2,RPN1,JPT2,STX12,ZBTB33,LIG3,SLC1A1,CYBC1,PYGM,BCCIP,NMI,SRPK2,ROCK1,SMURF1,MORF4L1,GJB2,RPF2,FGFR1OP2,DNAJC10,EIF3G,THUMPD1,BANF1,RNF113A,PRDX6,CWF19L1,RBM22,CFTR,PLP2,USE1,SDCBP,RPA2,HEXIM1,GSTP1,PRKCA,UBE2M,NDUFB4,CAMLG,RHAG,TRAPPC3,AKR1B1,FA2H,DNAJC1,ARL6IP5,CDC5L,DKC1,TMPO,PGAM1,CENPP,ORMDL3,TMEM107,CSNK2A1,SLC35A1,TMEM11,USP15,RPS2,TCEA2,RUSF1,NOSIP,ABCE1,KPNA2,SRPRB,H2AX,SFTPC,NFE2L2,TFRC,RNF8,GTF2F2,PSMD6,SNRNP40,ATP6AP2,PAPOLA,FAXDC2,FOS,SLU7,AKAP1,RAB5A,STAU1,EMC1,HNRNPA0,SAP18,GOSR2,VAMP1,SEC22A,FDFT1,PIH1D1,SRSF1,EED,PAIP1,LANCL1,COX14,PLPP4,AGR2,TOP2B,CHCHD2,LEPROTL1,PPIL3,RANBP1,SUPT5H,ISG15,SMNDC1,CRKL,ZRANB2,VAMP3,PLP1,PTEN,UBE2I,RTRAF,TMEM74,TXN,SEC63,SEC13,CREB3,RETSAT,PPP1CC,USP14,KPNA6,NONO,RUNX1,NTAQ1,CHORDC1,REEP6,NAPA,ORMDL1,SIRT7,MME,MTDH,HMGB1,GTF2I,CERS2,TMEM209,NHP2,EDDM3B,CCND1,FAM161A,RBFOX2,SAP30BP,CNP,EDF1,GRM2,GHITM,LMNA,CDK1,TOX4,PAK5,ZMYM6,TM9SF1,MAP2K6,ETV6,H2AZ1,SRPRA,HSD17B11,TOP1,PRNP,MAPRE2,CAV1,FAM118B,GMPPB,TMEM199,CALR,GTF2E1,HDAC6,PSMD7,IZUMO2,TMEM42,STX8,TMX3,EMC2,UNC50,THRAP3,TSPAN7,MDC1,GALNT2,OLA1,SFT2D2,RNF20,CCDC47,SERPINB9,SMAD1,ING1,LBR,PPME1,ILF2,RAN,RBBP4,TNPO3,CUL3,MCM4,ZDHHC24,RIOK2,LMNB1,FCER1G,CYB561,NUP50,HACD1,NMRAL1,GPC1,UNC45A,TNFSF12,H1-5,TIMM13,FAM3C,CMTM7,TMEM14A,PHB1,FOLR1,HP1BP3,COPS2,CYB5A,GJA1,SPTAN1,KCTD10,BUD31,NOP58,LRWD1,TMEM208,DPY30,CLPX,PRPF19,FATE1,KDM2A,PSMD10,DDX23,FXYD6,PDCD10,TMT1A,ERP29,TRIM37,RBBP7,TRIM26,EMC8,G3BP1,RFC2,MCM6,SRSF4,MARCKSL1,FEN1,NUP153,CTSA,VAMP2,STIM1,EZH2,PLD3,CYB5B,TMEM14B,RBPJ |
| 1.182e-20 | -45.88 | RPL10 (ribosomal protein L10) | protein interactions | 6134 | 665 | 297 | 19454 | 5460 |
EXOSC4,RNF113A,RBM23,SNAPC1,RPL27,BAP1,BANF1,HSPA5,RPS15,MRPL41,MRPL40,MRPL10,CFTR,HEXIM1,PRKCA,TFB1M,WWP1,PHAX,RPS3,PSPC1,BCCIP,RSL24D1,SRC,MRPS21,RPL10L,RPS17,RPF2,SMARCA5,MORF4L1,RPL7A,UBE2H,EIF3G,ATP1B3,MRPS16,RC3H2,MRPS18B,RPL3,DHX9,MRPL52,MAP1B,PDRG1,MEPCE,RPL17,MRPS33,IMP4,UBL4A,RRM1,RPSA,MRPL47,RBM34,DNAJC2,MRPS9,SYNCRIP,GTF2B,RPL32,ALYREF,DKC1,TMPO,MALSU1,RBM42,SURF6,RPS16,CAND1,FZR1,TMA16,CSNK2A1,COPS5,ENY2,CMSS1,RPS2,RPL10A,SNRNP70,RPL24,SF3B1,DDX5,RFC4,PACSIN3,MRPS7,UFL1,STAU1,RPL27A,MTF1,NUFIP2,TRMT112,PIH1D1,MRPS18A,MAP2K1,UBAC2,MRPL13,CMTR1,ESR2,RPL10,KBTBD6,MATR3,BTF3,MYC,SFN,RPS26,GTPBP2,MCAT,FTSJ3,MRPS25,H1-10,RTCB,RPL31,PABPC1,RBM3,TOP2B,SDHC,PFDN1,RPS4X,KRAS,ROCK2,RPS7,TRMT1L,TOP3B,RPS23,AAMP,RPL18,NOB1,MEAF6,RPS10,SUMO2,LYAR,MRPL9,CTNNB1,DDRGK1,IFI16,BAZ1B,DDX50,PFDN5,RPL6,WWP2,RIOX2,DDX1,DRG1,MAGOH,AGR2,FLCN,SIRT7,PNO1,UTP23,AATF,MRPL20,BRIX1,NF2,NPM3,MRPL17,FBXW7,HMGB1,RPL4,CDK7,RPS14,PIP5K1A,TPT1,RPLP0,NOL7,RPL26L1,ZNF574,MRPS34,COX6C,METTL14,RTRAF,GSK3A,PRKRA,RPS20,PTEN,RPS12,CCNF,INPP5K,PELP1,FBLN5,EIF2AK2,METAP2,EIF4A3,VIRMA,RPL22,DEK,NDN,ZNF622,RPL13A,YES1,FBXO7,RPL26,PPP1CC,RPL23A,MRPS18C,RPS13,MRPL22,SMN1,EIF3E,PAK1IP1,VRK1,FARSA,LBR,MLLT6,RPL15,FNTB,MRPL11,YTHDF2,ILF2,SRP72,CTDSPL2,RPL12,SRPRA,SRP14,RCHY1,ARL10,KRR1,MDM2,NCBP2,MRPL24,RPL35A,ARF6,PRNP,EIF2B2,HDAC6,ZMYND11,MPG,MOV10,EMC4,CRY1,EMG1,G3BP2,FTL,TSR3,NOP53,MRPL57,YTHDF1,WDR77,H1-5,NOTCH2,SLC25A3,APOBEC3C,EMC9,LARP4B,RPL37A,RPS9,SEC61B,GGPS1,RPL19,SNRPB2,MRPL23,RPF1,RPL35,RPL7L1,TAB1,ZNF668,MRPL16,RFC5,PRPF31,RPS29,CUL3,NOP16,RPS5,PFDN6,FAS,BRCA1,NOA1,RPS24,MRPS11,RPS27A,RFC3,RFC2,RAD21,G3BP1,TRIM37,RPL29,B3GNT2,EIF1AX,RPS11,MTMR2,EZH2,NGB,CHMP4C,HP1BP3,RPLP1,RPLP2,RPL8,WDR6,RPL9,FOLR1,PHB1,MRTO4,EGLN3,CNTROB,KIAA0232,NOP58,RPL7,MAP3K14,MRPS35,RB1CC1,MRPS26,RPL23,DICER1,PDAP1,MRPL18 |
| 1.190e-20 | -45.88 | regulation of protein metabolic process | biological process | GO:0051246 | 2218 | 844 | 18204 | 5365 |
DERL1,BAD,DEFB114,ABCE1,DEDD,DVL2,PPP1R8,GSK3A,CRY1,PKIB,TSPAN15,LRP6,BCL2L1,PTEN,JAK2,CARTPT,DIRAS2,UBE2N,SLC8A1,CRKL,MSN,CDK12,ARRDC3,CTDSP1,PLAA,SKP1,PSMC3,ATP5IF1,MIR221,MIR206,EIF2AK2,AATF,ODAM,SNX12,CCNI,LSM14B,COPS7B,GPX1,CYFIP2,CRTAP,SLC1A1,CTNNB1,CTSK,HYAL2,PIK3R3,EIF3D,PACSIN3,BOK,EP300,DR1,MAGOH,PDCD10,KHDC1,TANK,SMAD4,RNF128,GABARAP,TNFSF15,NOP53,SERPIND1,MIR1271,UBE2V1,UBE2V2,IREB2,ZNF592,RMND1,PMAIP1,MIR210,CD36,EIF4E3,BCL2A1,SERPINB9,MIR30B,MIR21,MTG2,RPS2,LILRA2,ELP6,NGDN,SYNCRIP,CREBL2,RHOBTB3,TSPAN17,TIA1,UBE2B,RGCC,NOS1AP,MOB3C,SMURF1,RTN4,EMP2,MIR107,UBB,CAMLG,COPS7A,ERP29,SERPINA1,FGR,UBE3A,IL12B,YWHAG,IFNGR1,FLOT1,PELI1,SERPINA5,TRAF7,VEGFC,EEF1A1,HSPD1,AURKAIP1,LDLR,ENO1,ROPN1B,MIR186,P3H1,PABPC1,EIF2S1,TESK1,CRADD,WBP1L,NFKB1,PML,HINT2,PRSS37,CHI3L1,DISC1,HCLS1,MIR378A,TRIB1,CCL19,GADD45A,TRAF6,FXR2,CAMK2N2,CCNF,FKTN,MIR181D,GSKIP,TFRC,TAF9,RHBDD3,HNRNPD,RAP1A,EIF4A3,SERPINB1,SMAD3,MIR24-1,DUSP22,STK38,NKX3-1,ELP3,RPS7,RALB,MINAR1,CLU,MIR205,MIR29A,UBASH3B,SEMA7A,MIR181C,IVNS1ABP,MIRLET7I,PRMT6,MPV17L2,NFE2L2,TICAM1,EIF3K,RGP1,METTL14,EIF2B5,NBN,EIF4EBP3,MIR153-1,TLR8,IFI16,NTRK3,NTRK2,ITM2B,BRMS1,TRIM3,MIR100,MIR135B,OAZ3,IFNG,TAB2,STX5,DTL,ATF4,TRIM21,LEP,SQSTM1,POLR2G,TCOF1,PHB2,HEXIM1,MIR148B,SRC,CDK20,ANGPT1,SERPINH1,PIWIL3,SUMO2,EIF1B,TNFSF12,FAM162A,SUMO1,COPS5,DIRAS3,RIT2,MACROH2A1,ATP2B4,MIR200C,PFDN2,MAD2L1,MMD,USP14,PICALM,PYM1,HSPE1,CSTA,CSTB,CIRBP,TADA3,MIR20A,CCL21,SPRED2,NCK1,FGF10,SEC22B,TGFB2,CHP1,MIR144,METAP1,DBNDD1,SVIP,KRAS,TNFSF18,PROX1,ADTRP,GREM1,MIR152,PIWIL2,TPPP,SNX33,PXYLP1,DYRK1A,USP13,RAP2B,GCLC,SOX2,PTPN22,TM4SF20,CAV3,FKBP1B,ODC1,VGLL4,CDKN2D,RAB1A,CD28,AGAP2,HSP90AB1,TAB1,MTG1,USP8,PFDN6,IFNB1,CAV1,SOCS3,HBEGF,CD4,RPS27L,LILRB4,PSEN1,MTM1,PPP1R2,ARL6IP5,UBE2I,IDE,SNRNP70,IFT57,SNX3,SERPINB6,MIR31,COPS4,ALKBH5,PKIG,MIR208A,CNKSR3,RUNX1,CDC20,DAPK1,HSPB1,ZER1,MYC,MIR126,IER3,MIR106B,ITM2A,SPON1,CTDSP2,CDK5R1,SOCS4,HSP90AA1,INPP5K,HTR2A,PDCD5,PSRC1,DAP,STRADB,ADNP,FBXW11,HSP90B1,USP16,TNFRSF14,PSMD10,DCUN1D1,PSMD14,ACOT8,POMT2,F2,EIF4E2,AZIN2,RAD23B,PSME1,LDB1,ACVR1,ETF1,TRIM6,RPS3,EEF2,PPP1R1B,CDKN2C,TRAF2,CX3CR1,MIR145,RAF1,ROCK2,IL10,MAP3K11,DDRGK1,FGF17,POLDIP3,ADIPOQ,PYCARD,HRAS,MIR361,AGER,LARP4B,BCCIP,S100A10,CAB39,VPS28,RGS2,YTHDF1,HMGB1,CORO1C,MIR495,IL7,IL3,UPF3B,EZH2,CHRNA7,YTHDF2,FBXO22,EIF4H,NCSTN,IKBKB,IL34,TGFB1I1,EGR1,GAPDH,CNOT7,MIR28,SERPINA3,CLN8,EPO,CCDC22,CCNA2,CSNK1A1,RPL23,PAQR3,SP1,DESI1,PPARG,MIR106A,SESN2,MIR711,GPNMB,FAXDC2,BTG2,TSPO,HECTD1,GABARAPL2,RAP2A,COP1,MIR34A,FHIT,ATG101,IL13,IL21,CLEC7A,SVBP,SPPL3,CTSC,FKBP8,MIR133B,CCNY,PFDN1,DIPK2A,TAF7,TRIM27,ENC1,MIR590,PTPN11,HUWE1,ADORA1,FGF22,PIWIL4,P2RY1,FGFR1,PTPRQ,PSENEN,MIR448,RGMA,PARL,DIO2,MIR10B,CDK5RAP3,EGLN2,PSMA3,PRKCE,NR1H2,FGF1,MIR125A,PCSK9,NRP1,TSG101,UBE2D1,SOD1,PAIP2,CCND1,CAAP1,MIRLET7B,TGFBR2,IL2,PAK2,FAS,PID1,ANP32B,KIT,TSPAN5,RPL13A,PFDN4,TOLLIP,EIF4A2,INPP5E,MT3,MIR877,CCND3,MIR345,GH1,TNFAIP3,GSTP1,BAK1,TXN,SIRT7,CALR,NFKBIA,APH1A,IGF1,SPRED1,CNOT2,RPL26,EIF4B,ITGA2,IFNA13,RPS4X,ACO1,SLCO3A1,TLR6,AIFM1,AKT1,SIAH2,IL1B,ELAVL4,MIR182,FAM107A,WNT7A,PRKAG1,UCN,CD80,CLEC6A,MIR204,NMI,WNT10B,MAD2L2,SMYD3,PAX6,RIGI,TNIK,UBE2S,IFNA2,MIR96,DNAJB2,DNAJC3,DNAJB6,SFN,CDKN3,LCP2,EHD4,AQP11,PPP2R5A,SMG8,MIR148A,RPL10,METTL18,MCL1,TNFRSF1B,IFNK,PLCB1,TLR9,ATG7,HDAC3,PAIP1,GNAQ,IFNA10,CD86,MMP9,MIR379,BAX,EIF4E,USP38,TOM1L1,IL6,MOB3B,UBE2K,DDX1,MMP14,MAGEC2,ACVR1C,DAPK3,KLHL25,SNTA1,PRNP,SPRY1,HAX1,CLIP3,UHMK1,ERRFI1,PPP1R12A,AKT2,COPS2,DCUN1D3,PIH1D1,DRD1,MIR16-1,DNAJC1,ARL2BP,EIF5B,MAPKAPK5,NHERF1,IGF2BP1,MAP2K6,PHF23,SEMG2,PSMC5,DUSP6,XRCC5,TBK1,VIP,FAM161A,DIRAS1,PIAS1,MYLIP,G6PD,RARRES2,CYP1B1,TACO1,CCNH,MRPL13,GTDC1,SERTAD1,LAMP3,LACRT,EGLN3,CNOT6L,PSMC4,DUSP1,BIRC2,YES1,UBE2L3,TNRC6C,TRIM32,MIR101-1,XPO1,ATRAID,DCUN1D5,VSIR,STK11,CCAR2,SELENOT,MALSU1,FBXW7,HDAC6,SGF29,S100A8,PRR5L,CD40,BOLL,PITHD1,FGF16,SYK,PSMC1,NLRP1,NF2,CEP85,TIMP1,MIR874,CTSA,IL23A,VEGFA,FGF23,EIF3E,PRELID1,MTPN,MIR298,MIR455,NSMCE3,IL15,MIR137,BEX3,CCNB1,CAMK1,MIR218-1,PSMD1,OSM,PRKACB,CUL3,CAMP,MIR15A,SERPINB11,ROCK1,PDCD4,CACUL1,NTF4,TCIM,IFT52,SPOPL,PIK3CA,IL17F,MIR939,THY1,PIK3CG,FASLG,RNF41,ASB11,UQCC2,BZW2,SERPINI1,CSH1,RB1CC1,IL18,FCGR1A,HGS,MAP2K1,MIR339,PELO,KDM1A,IL5,EIF4EBP2,FKBP1A,MIR29C,TLR7,DLG3,CNOT6,IGBP1,TOPORS,FIS1,TMEM168,CBL,NDFIP1,STAT2,SOX9,AZIN1,IL1R2,PAEP,CPEB1,CSNK2A1,RGN,MIR9-1,NEDD8,ZFAND2A,MAP2K3,DUSP3,OSBP,DPEP1,MIR346,C9orf72,ADRB2,CCR7,ISG15,SPOCK1,DHX9,DKK1,RAB1B,RABL3,USP5,EFNA5,SWAP70,RPS9,MAVS,FURIN,ARPP19,CD81,MIR146A,IGFBP3,SERPINB10,NPTN,IL4,HTRA2,OPHN1,HSPA5,SOCS5,SPOP,PPIA,FZR1,DUSP19,LRRTM3,AGO1,CRYAB,NUPR1,SECISBP2L,CSNK1E,FERMT2,TIMP3,RCHY1,SFRP1,FLCN,RTRAF,TLR3,EPHA4,RPS14,CST3,EFNA3,CCL5,RNF34,PARD6A,IL6ST,CSF2,RFX4,MAP3K12,IL12A,BCL10,MIR132,TPD52L1,RWDD3,EIF5A2,MIF,TYMS,NLRP2,RB1,ILK,NDN,CDKN1A,LSM14A,CTSD,CLDN3,CASC3,NLRP3,PAIP2B,MIR214,MIR17,YWHAB,PHB1,NGRN,CX3CL1,MUL1,ACTB,CAMK2N1,FGF3,SHMT1,TNF,PKIA,PSMD3,DUSP10,MIR98,TBC1D24,OAZ2,PFDN5,HFE,CLDN4,SH3BGRL,CDK5,HEXIM2,FGF7,HMG20A,STUB1,DNAJC10,EIF2B2,FAF1,PIWIL1,PSMB9,IFRD2,RBCK1,TRIM44,RNF139,LGALS3,DET1,PSME2,SGTA,UFL1,MIR212,RBM3,MIR503,SUFU,NQO1,PLGRKT,IMPACT,CDKN1B,NCBP2,LEPR,OAZ1,MIR1-1,STK4,TP53,TNFSF10,MDM2,DLG4,APLNR,TLR4,IFI6,ZBED3,KLF4,MIR147A,GHR,BAG2,PTPN1,HSPA8,PPIB,RAP2C,CNOT8,ITGAV,MIR26B,TIMP4 |
| 1.320e-20 | -45.77 | MAP1LC3B (microtubule associated protein 1 light chain 3 beta) | protein interactions | 81631 | 541 | 252 | 19454 | 5460 |
DNAJC7,BRD3,KXD1,ATP5MG,ATP5PD,MYBL2,UBE2B,ACTR2,MAP1LC3B,RPL15,CMPK1,CCDC47,TBK1,IRGQ,GBE1,SOCS2,ARF4,PTGES3,RIGI,ABHD10,MDC1,SEM1,ATG4A,MRFAP1,SEPTIN7,SLC25A10,RAB1A,TCOF1,AP2A1,HERC4,KPNA6,PPP1CC,USP14,UBE2L3,GNAI2,RAB14,TXN,TMOD3,YES1,ARMC6,GSK3A,WDR45,VAMP3,OPTN,TUBA1B,EIF4A3,PDCL,HNRNPH3,CDK1,UQCRC1,SYNRG,GABARAPL2,FTH1,SYNGR2,RPS14,ATG16L1,PIP5K1A,CCND1,MBD3,GABARAP,ATG4C,B2M,FLCN,SQSTM1,ARPC2,RPA3,RETREG2,PNO1,MRPS26,RB1CC1,RHOG,CSTA,CDK5RAP3,TRAF6,ATG7,PDIA3,CLPX,TAF7,PRDX1,ATG9A,IFIH1,BABAM1,MAP1S,NDUFS8,STK3,DHX15,SNX18,RPL7,HYPK,SPTAN1,XPO5,GJA1,MAP1LC3A,RPLP2,BRD9,RPLP1,WDR6,STX12,VAMP2,NGB,YIPF3,ERLIN2,ARFGAP1,RPS27A,RETREG1,EMC8,DHX16,NEK9,SCYL2,RPS5,HSP90AA1,PFDN2,BLVRA,NOA1,LMNB1,RHEB,RAB11A,CUL3,NDUFAF4,PRRC2A,TUBB,AP2M1,RAN,CNOT6,TBC1D17,ANXA7,APOBEC3C,ADNP,H1-5,FTL,UNC45A,SRM,HADHA,EVA1A,LANCL2,LYPLAL1,TSPO,STX6,CAND1,VTI1B,RPS16,ADD1,PREP,CDK6,STT3A,ALYREF,UBE2N,RAD1,TFRC,WBP11,YIPF4,RRM1,MTCH2,TP53,STX11,FKBP8,TMEM33,ERO1A,ABCE1,RAB13,DHX9,MAP1B,PSME1,TBC1D25,SERPINB1,GORASP2,RAB2A,TRIM32,CCNB1,SRC,BCCIP,STX10,CCSER2,PSMA6,ACACA,HECTD1,RPA2,EIF2B3,STX17,SAMM50,TOMM20,BNIP3L,WDR3,BAP1,TEX264,IRF3,NLE1,PML,HSPB1,FKBP4,YWHAG,TBC1D5,CTNNB1,STK4,GSTM3,DDX50,LAMP2,PTDSS1,RAB5C,VAMP7,HSP90AB1,AFTPH,TCP1,EED,WDR82,CD63,SMARCB1,HGS,RPL18,AAMP,RPS23,PIR,TPPP,EEF2,RPL28,DCTPP1,VAMP8,RAB18,TRIM21,MYO1B,RABGGTB,RTCB,RINT1,H1-1,CCT2,ATG3,THAP7,ATG101,EPS8,ATP6AP2,KBTBD6,STAT1,TAMM41,MATR3,NDFIP1,FBXO22,TAX1BP1,TRMT11,BST2,NUFIP2,CSNK1A1,SEC62,FUNDC1,TRA2B,EMC1,PHB2,ADRB2,GPHN,HSPA8,SF3B1,TMEM160,RPS28 |
| 1.370e-20 | -45.74 | mitochondrial membrane | cellular component | GO:0031966 | 752 | 336 | 19108 | 5553 |
NDUFS3,TMEM70,DNAJC30,COX6B1,CIBAR1,ARMCX3,MRPS35,CYB5A,HAX1,RNF144B,SLC25A46,NDUFS8,VAMP1,CISD1,CLU,TIMMDC1,MRPL10,NDUFAF3,TIMM8B,TMX2,UQCC3,GRPEL1,BAD,MRPL12,LGALS3,ALPL,PNPLA8,MTCH2,NDUFA1,FGR,MIEF1,NRP1,MRPL17,SFXN1,MRPL49,TIMM13,CYP27A1,ATP5F1D,COQ8B,SLC41A3,APOO,AURKAIP1,SLC25A20,MRPS34,COX10,KRAS,SLC25A27,NDUFB8,CHCHD6,SLC25A42,RPS3,MPC1,ADCK1,SLC25A10,HADHA,MRPL20,IFI27,ATP5F1A,UQCRC1,HINT2,TSPO,SLC39A9,EXD2,UBA52,COX11,HSPD1,UCP2,TAMM41,CYP11B2,MAIP1,MRPL33,RAB32,PTRH2,AGPAT5,MRPS18C,MRPL50,COX6C,LDHB,ARMCX1,RSAD2,NDUFA12,ATP5MK,BAX,MRPS18A,UBIAD1,DCAKD,PLAAT3,FUNDC1,SLC25A12,BAK1,TUFM,ATP5MG,ATP5MC3,TIMM23,DUSP21,CNR1,MTARC2,MUL1,SLC25A5,ELK1,NDUFA4,NDUFS2,PHB2,TRAF3IP3,MRPL16,TMEM11,NDUFB10,CRAT,RAC2,PMPCA,MRPS23,TWNK,COX8A,MTG2,MRPL9,COX4I1,SLC25A44,SRC,COX6A2,SORD,AGK,ARMCX2,GNPAT,GRPEL2,SPHK2,PLA2G4B,MRPL41,SYNJ2BP,TOMM40,UQCC2,DUSP18,COX16,TMEM126A,ACSL4,MGARP,THG1L,PDSS2,PTPMT1,PMAIP1,MRPL24,MRPS9,MPV17,MRPL51,COX6B2,PGRMC1,GPAM,MRPL57,STOML2,ATG9A,GHITM,HTRA2,CHCHD3,MCL1,TOMM22,SLC25A28,FIS1,STARD13,MFN1,CPT2,SMDT1,SDHB,CHCHD1,TMEM126B,COQ10B,SLC25A32,NDUFAB1,GPD2,PHB1,TIMM21,DELE1,SDHC,FAM162A,MGST3,CPT1B,PLN,FUNDC2,SLC25A14,ATP5F1B,NDUFS6,TOMM7,PSEN1,UQCR11,PPP1CC,CYC1,NDUFV2,NDUFB4,SLC25A39,CYP11B1,MRPL36,MTX2,SMCP,SLC25A4,TIMM10,ATP5F1E,TMEM177,SLC11A2,NDUFB5,ABHD6,MRPL53,BCL2L1,ARMC1,TOMM20,ATP5PO,UQCRC2,SLC25A1,ABCG2,TIMM8A,TOMM6,MRPS16,TIMM17A,RAF1,COX5A,QTRT2,MRPL52,SLC25A21,CCDC90B,ROMO1,UBB,MRPL47,MRPS17,NDUFA2,MPV17L2,MRPS7,SLC25A45,MT3,MAP1LC3B,BECN1,SARM1,CLPX,COX4I2,CARD19,DNAJC19,PGR,PPIF,TRMT10B,MRPL18,TOMM70,MRPL40,PDE2A,DEGS1,RNF5,PARL,NGRN,RPS27A,SFXN2,COX14,IMMP2L,CYP1A1,COX7A1,PTPN1,NOA1,HIGD2A,SLC25A26,PLSCR3,NDUFAF2,NDUFAF4,MRPL13,NDUFAF6,FKBP8,SAMM50,FATE1,PGS1,BNIP3L,MAVS,ATP5PB,GABBR1,EFHD1,IFI6,TMEM14A,MRPS11,DMPK,NME4,MRPS26,MTG1,ATP5PF,MTHFD2L,MRPL23,TAFAZZIN,NDUFC2,MRPS33,KGD4,SLC25A11,CNP,SH3GLB1,MRPL34,MARCHF5,MRPS28,STARD7,SLC25A31,NDUFA5,COX7B,TMEM14B,BCS1L,NDUFB6,MRPS25,CHDH,RMDN3,COA1,SLC25A51,PRKCA,USP30,MRPL11,GK2,CYB5B,MRPS21,UQCC6,AKAP1,ATP5PD,COX7B2,SNN,VDAC1,AIFM1,NDUFB7,CYP27B1,SLC25A3,UFL1,UQCRH,ZDHHC8,TMBIM6,UQCRQ,SLC25A23,SLC25A24,COX20,TMEM160,ATP5MC1,BOK,TYMS,MRPS18B,TOMM40L,BCL2A1,ATAD1,EPHA4,VDAC2,MRPL22,CYB5R3,TIMM29 |
| 1.393e-20 | -45.72 | SMURF1 (SMAD specific E3 ubiquitin protein ligase 1) | protein interactions | 57154 | 533 | 249 | 19454 | 5460 |
MAT2A,RPF2,SUB1,CFL1,RPS17,NR2E1,DNAJC10,PTTG1,RPS3,PSMC5,ING2,MACROH2A1,MAP3K3,ADRM1,PPAT,SMURF1,ROCK1,SPTBN1,PAQR3,NEK2,ZNF326,WWP1,UBE2M,PRKCA,PARD6A,UTP15,ELOF1,HNRNPH2,EXOSC4,LCP1,RPS15,UBE2K,STK38,HSPA5,MARS1,PLEKHO1,RBM17,SMAD4,SNRNP70,RPL24,AKAP8L,USP15,EEF1B2,SYNCRIP,GTF2B,ITK,ARL4D,FZR1,RPS16,TMPO,DKC1,SLAIN2,TP53,ACTR1A,MINDY3,ACVR1,RBM34,BMPR2,CCM2,CCDC69,PSMC3,MAP1B,MYD88,DHX9,PSMA5,NEDD8,CDC40,HNRNPK,RBCK1,TGFBR2,FGF12,CAPZA1,RPL17,PSMA4,LDHB,HNRNPAB,RPL39,SNRPB,CIRBP,CCT2,FTSJ3,VDAC2,PRMT5,STAT1,PSMD4,NDFIP1,HECW1,POLR2B,ACAP2,RNF141,FBXO42,TOM1L2,EIF4B,SNRPA,BMPR1A,XRCC5,SF3B1,HSPA8,DDX5,UBE2D3,HNRNPA0,EEF1G,MRPS7,XPO1,CTNNB1,AK2,ARHGAP5,ANKRD50,TNIK,SRSF1,GYS1,HNRNPL,RPS10,SNRPA1,SNRPD3,TCP1,CCT7,NAA16,PTS,TUBA1A,TRAF2,EEF2,TUBB4B,TAPT1,ZRANB2,FBXO3,RPL31,CCT8,EFNB1,LDLRAD4,TRIM11,PDIA6,HNRNPF,ARHGAP15,CCAR1,RPS4X,PRPS1,STK38L,TUFM,IVNS1ABP,SMAD2,STUB1,CTTN,CMBL,RPS12,PTEN,MSN,RPS20,RPL13A,FERMT2,UBE2L3,UBB,RPL22,SMAD5,VIRMA,JUNB,RPS14,PSMC4,SF3A1,PIP5K1A,UBA52,ELP3,LMNA,JUP,PICALM,OXSR1,MAVS,SQSTM1,PFKFB2,CXXC1,BMPR1B,DNAJC7,FGR,OSBPL8,ETV6,SMAD3,KRR1,LDLR,PWP2,MDM2,MRPS23,TBK1,EEF1A1,ING1,DDX39A,SMAD1,UBE2V1,NKRF,TCOF1,PAK1IP1,THRAP3,TOM1,RPS13,CTNND1,ARF4,EIF3E,PTGES3,PRPF31,SENP8,RHOB,RPS5,SETD7,RIT1,SNRPD1,SNRPD2,RPS9,TAB1,ACTB,RPL35,TUBB,CHCHD3,GNB1,USP5,WDR77,SLC25A3,IMPACT,RTKN,EMG1,RNF11,FBXO30,UBXN6,HNRNPA1,GNG11,SKIC8,UBE2D1,TRAF6,HNRNPD,RPL23,WDR6,SASH3,HP1BP3,SPTAN1,PPP2R1A,FAF2,OTUD6B,GDI2,RPS11,POLR2C,SLC25A5,NUDT5,HSPD1,HNRNPA2B1,JAK1,RPS24,ACVR1B,TRIM37,SRSF4,RPS27A,SSRP1 |
| 1.554e-20 | -45.61 | nef (Nef) | protein interactions | 156110 | 802 | 345 | 19454 | 5460 |
PRKCE,CCR2,TFEB,SRC,RPS3,IL2RA,HFE,SNTA1,ATP1A1,ATRAID,AKT3,HSPA5,ARHGEF6,PRDX6,RAB9A,TLR2,HNRNPH2,CD46,SDCBP,VPS4B,MRC1,PRKCA,CDC5L,CD28,ITK,SYNCRIP,CEBPG,CD4,BECN1,CXCR1,IFNA2,USP15,CD247,RPS2,ACOT8,CCL5,SRPRB,IL12A,IL12B,SLC25A11,RPL3,BMPR2,TFRC,CD209,TBC1D4,CCL20,CD14,DUSP1,NFKBIA,BST2,SF3B4,ICAM1,CCL24,CXCL1,STAU1,HNRNPA0,FOS,SNRPA,RAB5A,HSPA8,IL4,PAK2,CD59,TCP1,ELK1,SRSF1,SDC4,RXRG,EED,IKBKB,DRG1,VDAC1,IFNG,CD83,PABPC1,GPM6B,RPL18,ADCY3,FASLG,TRAF2,YES1,TXN,LDHA,IFNA10,VKORC1L1,SH3BP4,EIF4A3,TNFRSF1B,VAMP3,RPS20,PTEN,GSK3A,XPOT,CTSD,NONO,ATP5F1A,RPL4,B2M,GABARAP,SQSTM1,MAVS,HSP90B1,CCL19,RPLP0,CCND1,ATG16L1,CCL3,ARF6,CD151,CAV1,HACD3,AIFM1,EXOC2,CD36,NFKB1,BMPR1B,TF,WASL,CCL2,CD80,TSPAN7,IL6,EIF3E,RNF20,ARF4,EHD4,STX8,SLC6A3,SRP72,SEMA7A,ILF2,MAP1LC3B,EEF1A1,RPL19,RAN,ARF1,CPSF1,AP2M1,CD226,FAS,GPM6A,IL1B,FTL,WASF3,UPF3B,CXCR4,RNF7,ATP5PO,PPARG,VAV2,RPL7,SPTAN1,RAB11B,CSF2,SERINC3,PHB1,DNM2,THOC2,TSG101,IL10,TRAF6,DDX23,CD58,BCL2L1,LYZ,ICAM2,EIF3D,ADCY2,SRSF4,AP1M1,ATF3,AKT2,UBE3A,AP2S1,CYB5B,ELMO1,CXCR3,CDIPT,GNAO1,SEC61A1,IL15,MECP2,OAT,IGF2BP1,RPL7A,AKT1,PRKACB,CFL1,CFL2,IRF3,SNX22,CXCL8,CDC42,MIF,STX6,LCP2,ALYREF,RAC2,RPL24,IL21,CXCL12,GAPDH,CD81,FCGR2A,FCGR2B,HNRNPK,RPL17,CCR5,DHX9,PIK3CA,EXOC3,TP53,STAT1,STAT2,MATR3,RPL10,IRF2,VEGFA,CD3G,TNFRSF9,CCT2,SERPINH1,LDHB,HNRNPC,HNRNPAB,OSM,PHB2,EEF1G,PEBP1,BMPR1A,DDX39B,DDX5,SF3B1,MAP2K1,SYK,IL6ST,RPS10,CD63,ACHE,NCK1,IFNB1,FCGR1A,DDX1,CBL,PTDSS1,RAB5C,RPL6,IFI16,LAMP2,EXOC1,CTNNB1,HNRNPF,CXCL10,RPS4X,MMP9,PIK3CG,OAS1,PLS3,HGS,CCR1,SMARCB1,ETFB,HEXA,TUBA1A,GNAI2,UBE2L3,ENO1,EIF2AK2,SMPD2,IL2,NRP1,AP2A1,CD164,PIK3R2,PDHB,NF2,CCR3,IDH3A,PRKCB,AGAP1,HNRNPH3,XCL1,GABARAPL2,FTH1,IL18,CDK9,ACTA2,KRR1,HRAS,LDLR,RB1,MOV10,SFXN1,NKRF,IFNA13,CTLA4,AP1S2,ACTB,CD40LG,B4GAT1,SELL,CD86,BAD,RPS9,AP1G2,HSP90AA1,RAB11A,IRF1,CCR7,CD1D,HEXB,RRAGA,STXBP1,CDKN1A,SNX18,INA,DHX15,CD1A,PPIA,SRSF10,PRKCQ,PSMB4,RPL9,RPL8,MAP1LC3A,PDCD1,HNRNPD,VPS4A,PIK3R1,HNRNPA1,TNF,ARL5B,KIT,HNRNPA2B1,SLC25A5,SCYL2,ZYX,HSPD1,SRSF7,RPN1,RAF1,IFNGR1,RPL29,GABARAPL1,JUN |
| 1.741e-20 | -45.50 | PRMT1 (protein arginine methyltransferase 1) | protein interactions | 3276 | 886 | 374 | 19454 | 5460 |
RPL37A,RAN,CPSF1,SNRPB2,SPINDOC,MCM3,MCM4,CUL2,CUL3,RIT1,SKP1,IGSF21,G3BP2,MIR106A,COIL,IDH3B,WDR77,MIR141,PHB1,SPTAN1,CCAR2,RPL7,COPS7B,EIF3D,PSMD3,CLPX,PRPF19,PRDX1,MIR1-1,DDX23,UBE3A,JAK1,ZBTB14,G3BP1,EMC8,RBBP7,GFI1,E2F4,GNB1L,EZH2,RTRAF,EIF4A3,STUB1,MIR16-1,RPL13A,LDHA,KPNA6,AR,NONO,TUSC1,PPP1CC,TUFM,ZCCHC12,RUNX1,ATP5F1A,NTAQ1,CTSD,CA2,DCAF16,MIR145,IVNS1ABP,MTDH,PRPF4,SMC4,RPL4,PFKFB2,DGCR8,GTF2I,CNP,MIR1-2,RPS14,PSMC4,RBFOX2,RPLP0,HSP90B1,PTP4A2,LMNA,JUP,SHLD1,AIFM1,MIR106B,TOP1,HDAC6,DNAJC7,HSD17B10,ZC3H11A,SPSB1,EIF3E,PRDX4,THRAP3,EEF1A1,YTHDF2,ILF2,MIR20A,MIR17,PHKB,SNRNP40,ATP5F1B,PSMD4,CHTOP,H1-10,EP300,HDAC5,HSPA8,XRCC5,SNRPA,RANBP10,STAU1,PITHD1,PIH1D1,S100A8,CORO1C,SRSF1,FABP5,TCP1,FAM98A,CNOT8,MIR29C,MIR143,YWHAB,AGR2,RTCB,PDIA6,RUVBL2,RBM3,CCT8,PABPC1,POLDIP3,HNRNPDL,MIR155,KRAS,KIF2A,SUPT5H,RPL18,PSMC5,EIF2S2,PSMA6,RPS3,SMURF1,ROCK1,NR1I2,PPAT,ADRM1,HNRNPH2,EXOSC4,MIR10B,HSPA5,MIR107,MIR29A,KDM1A,NEK2,SPTBN1,UBE2M,ZNF326,BTG2,RPA2,SYNCRIP,CDC5L,SLAIN2,TMPO,DKC1,RBM17,KARS1,RPL10A,USP15,RPS2,SNRNP70,RPL3,MIR200A,CAPZA1,MIR16-2,KPNA2,ACTR1A,IPO8,TAB2,NEFL,ARPC3,RBM34,IK,SNRPD1,SNRPD2,VPS72,ERH,PRRC2A,MIRLET7D,TAB1,ACTB,TUBB,PRDX2,RPS29,PRPF31,LSM14B,MIR363,HSP90AA1,YWHAZ,BRCA1,YTHDF1,NOP53,HSCB,ACTL6A,LARP4B,EMC9,PSMB7,RPL8,DHX15,EGLN3,INA,HNRNPA1,PDIA3,PDAP1,MRPS26,RB1CC1,HNRNPD,PPM1B,PCNA,PRPSAP1,MAEA,HNRNPA2B1,NEK9,SLC25A5,HSPD1,ZYX,RPS27A,PPP2R1A,CSNK1E,RAF1,SNRPE,ALB,ODR4,TUBA1B,CTTN,EIF2AK2,ENO1,CCNF,VIRMA,NDN,IFNAR1,RPL26,FBXO7,STK38L,CDC73,MIR34C,RPA3,FBXW7,MIR7-3,PDHB,SF3A1,HNRNPH3,RARS1,METTL14,DCTN4,MIR25,KRR1,THOC1,MOV10,MIR34A,NKRF,PPDPF,HUWE1,EXOSC8,MIR15A,PPARA,CCT5,TOPORS,SMU1,PRMT5,DLST,ACAP2,ESR2,LRIF1,STAT1,MATR3,CPSF2,SNRPB,BTF3,ATG101,PSMA4,HNRNPC,PRMT6,LDHB,HNRNPAB,MYC,MDH1,COP1,ATG3,CIRBP,CCT2,DDX5,SF3B1,JAKMIP1,DDX39B,EEF1G,UFL1,MED31,NUFIP2,EIF4B,WDR82,FUBP3,RBM5,CCT7,HSP90AB1,SNRPD3,SNRPA1,MIR9-1,HNRNPL,DBR1,YWHAG,NOL4,YWHAH,WWP2,RPL6,IFI16,MAGOH,ARMC8,MIR221,DDX1,EWSR1,TRIM21,MIR206,MIR9-2,ABCF1,LSM14A,PRPS1,TFG,RPS4X,RUVBL1,PSMA2,HNRNPF,EEF2,TUBA1A,H1-3,MIR222,ETFB,BTG1,TUBB4B,PLS3,CSNK2B,RNF187,PSPC1,STAT5A,RPL7A,UBE2H,CDKN2AIP,OAT,IGF2BP1,PDCD4,DLAT,PGK1,LSM12,PML,NBN,STK38,LUC7L3,ALYREF,CAND1,GAPDH,TPM3,API5,PPIL4,ENY2,MAP4,AKAP8L,RPL24,MIR9-3,DHX9,ZNF451,MAP1B,HNRNPK,H3C1,RPSA,TP53,CERK,DISC1,DDX42 |
| 1.817e-20 | -45.45 | HNRNPM (heterogeneous nuclear ribonucleoprotein M) | protein interactions | 4670 | 675 | 300 | 19454 | 5460 |
EEF2,RPS7,MIR222,DNAJC25,SOX2,ISG15,ARFGEF1,TOP3B,RPS23,RPL18,HGS,SMARCB1,MTA2,RTCB,MIR206,EWSR1,MIR9-2,ABCF1,RPL31,HNRNPDL,RPS4X,MIR155,HNRNPF,CTNNB1,DDRGK1,MIR29C,XPO1,YWHAG,WWP2,RPL6,MIR143,IFI16,GSTM3,MIR140,MAGOH,DDX1,POU5F1,MIR221,FKBP4,AGR2,MIR31,MIR214,EED,SRSF1,RAB31,MIR9-1,SUMO2,TCP1,SNRPA1,SNRPD3,HNRNPL,LMO3,SEC62,MTF1,FDFT1,PIH1D1,CSNK1A1,UBAC2,PPT1,PAK2,EP300,RAB5A,DDX5,HSPA8,SF3B1,RPS28,DDX39B,SLU7,SNRPA,RFC4,STAU1,B9D2,UFL1,FXR2,HNRNPA0,TRA2B,SNRPB,BTF3,SFN,PSMA4,HNRNPC,LMO2,MYC,SERPINH1,RPS26,PSMD14,SF3B4,MIRLET7B,CMTR1,LMBR1L,RPL10,PSMD6,MATR3,RPSA,TP53,RAP1A,UBL4A,FURIN,SLC25A24,NUPR1,DNAJC2,TFCP2,DHX9,MIR9-3,PSME1,SNIP1,MIR200A,MIR16-2,CAPZA1,MEPCE,MIRLET7C,CEACAM5,HNRNPK,PSMA5,API5,CD81,COPS5,RPL10A,PEBP4,RPS2,SNRNP70,ARL4D,ALYREF,MRPS9,SYNCRIP,CDC5L,MIR429,TMPO,MIRLET7G,RPS16,CAND1,DNAJC1,FZR1,CFTR,MIR34B,MIR7-1,HEXIM1,TFIP11,MIR21,SSR1,SAMM50,ZNF326,EIF2B3,RPA2,RNF113A,HNRNPH2,PPP1R26,PML,RPL27,MIR10B,BAP1,MIR29A,MIR107,MORF4L1,RPL7A,GSTK1,MAT2A,SMARCA5,UBE2H,RRP7A,ATP1A1,RC3H2,TRIM23,SPOP,MRPS28,PSPC1,UQCRC2,TRAF1,SRPK2,KCTD9,ERLIN2,JUN,B3GNT2,RPS11,NGB,CHMP4C,EZH2,RPS24,HNRNPA2B1,SSRP1,TNF,MAP3K14,TRA2A,ZNF207,HNRNPA1,PRPF19,RPL23,HNRNPD,MIR1-1,RB1CC1,MIR141,MAP1LC3A,PHB1,MIR7-2,MYEF2,CBFB,DHX15,NUP35,LRWD1,PPIA,CACYBP,RPL7,RFXANK,WDR77,EMC9,PPARG,MIR106A,MIR98,CUL3,CUL2,USP13,ILK,RPS5,MIR363,LMNB1,BRCA1,SNRPD1,RPL19,PRRC2A,SNRPB2,MIRLET7D,MRPL23,EEF1A1,MIR15A,MIR200C,CCT5,FBP1,TOPORS,ILF2,MIR17,TNFAIP8L1,MIR20A,RPL23A,FAF1,RAB1A,RPS13,VRK1,THRAP3,CTNNBL1,HDAC6,MOV10,MIR34A,CRBN,TNKS,MIR25,RCHY1,RPL12,CTDSPL2,MIR106B,CWC15,MDM2,CDK9,TOMM70,PTP4A3,TOP1,EIF2B2,MIR1-2,SF3A1,RPS14,RPLP0,RPL26L1,STOM,METTL14,LMNA,MIR34C,MTDH,RTN4,MIRLET7I,MIR205,RPA3,MBD3,MIR7-3,FBXW7,SMC4,GTF2I,NF2,NPM3,USP14,GMPS,DNAJC8,PPP1CC,NONO,AR,RUNX1,FBXO7,IVNS1ABP,MIR145,UBE2I,TRIM24,MSN,GSK3A,PRKRA,ENO1,EIF4A3,CCNF,MIR16-1,RPL22,SH3BGRL,NDN,TMOD3 |
| 1.959e-20 | -45.38 | UNK (unk zinc finger) | protein interactions | 85451 | 403 | 200 | 19454 | 5460 |
MDFI,CNOT2,CTNNB1,GPR85,CPEB1,YWHAG,CNOT8,XPO1,ARHGAP5,YWHAB,FUBP3,LAPTM4A,SIN3A,COMMD6,TCP1,HNRNPL,HSP90AB1,TOP3B,EEF2,GLE1,PLS3,ZRANB2,MTA2,PABPC1,LSM14A,CCT8,TOP2B,SDHC,RTCB,PDIA6,FBXO11,KRAS,HNRNPDL,TFG,LEPROTL1,COX7B,HNRNPAB,BAG3,PNRC1,SLC38A1,SRXN1,NDFIP1,MATR3,STAT1,ATP6AP2,CBX5,PLAA,NUFIP2,RAB5A,DDX5,SF3B1,STAU1,RER1,PHB2,FXR2,TRA2B,COX5A,TPM3,SMG8,ZDHHC15,DSTN,MCL1,RPS27L,CAND1,TMPO,SLC38A2,TNRC6C,RAP1A,YIPF4,CBX3,SLC16A1,CSE1L,SUB1,CEP85,BFAR,RC3H2,PDCD4,MFSD14B,RPS3,MACROH2A1,CSNK2B,CHMP5,CTSB,EIF4H,CSTF3,SPTBN1,AGO1,CDC42,SDCBP,LUC7L3,ITM2B,SMG5,LSM12,KDM1A,UGP2,DPY30,MARCHF5,SAV1,VPS26A,PDIA3,EMC6,UBE2D1,TMEM30A,PDCD10,KRT8,IGBP1,TYMS,DHX15,MACO1,GFPT1,GDI2,PPID,SNRPE,GPBP1L1,MTMR2,HSPD1,MKLN1,ZC3H7A,G3BP1,RAD21,UBE2A,RRN3,CUL3,CUL2,JPT1,YWHAZ,HSP90AA1,CNIH4,ARF1,SERINC1,TUBB,ACTB,SPCS1,EIF4A2,PRRC2A,TNPO3,GGPS1,PPP1CB,PRDX3,LARP4B,ATP5PO,SLC25A3,GTF2H5,ATP5MK,MCRIP2,RLIM,ATP5IF1,TXNL1,MCMBP,YTHDF1,UCHL3,G3BP2,NRBF2,BRD3,FOXP1,SMG9,PSMB1,TOMM70,YTHDF2,CCT5,FAM13B,EEF1A1,MLLT6,ACTR2,UBE2B,GARRE1,RAB1A,HINT1,HAPSTR1,HSPE1,CNOT7,HUWE1,EIF3E,PTGES3,MSH6,ARF4,CNOT6L,PSEN1,USP14,KPNA6,ATP5F1A,MAPRE1,CTNNA1,SMAP2,CYRIB,ACAT1,GSK3A,LDHA,MGST3,RAB14,TXN,UBA52,TXNL4A,RBFOX2,PICALM,GHITM,PTP4A2,RPA3,ARPC2,RTN4 |
| 1.998e-20 | -45.36 | biliary_tract | COSMIC cancer mutations | biliary_tract | 15309 | 4548 | 16828 | 4835 |
SPOPL,SYT2,LEPROTL1,TMEM95,PRPF31,BMP1,NR1H2,MMADHC,TTC1,PHB2,EDNRA,ST6GALNAC3,TBC1D24,SLC25A44,ZNF692,THY1,YWHAB,PSMD14,SESN3,CDSN,LRWD1,ARRDC3,ZCCHC12,NFYB,SLC25A17,LILRA1,DAPK1,PDE1A,KCNQ5,TPBG,STXBP6,RRAS2,ATL1,SNCB,TPT1,RERG,FRS3,POLR3F,RPL35,RNF20,COPS7A,PPARA,GPR15,OTUD6A,STOML2,TOR1AIP2,NUP153,MICB,GTF2A2,ACTL9,EYA3,DUSP26,RNF39,PBLD,HDAC6,TMEM176A,ANAPC13,CNTNAP1,AGPAT1,BTG1,ZMYM4,EIF2S2,CHMP5,ASB3,USP14,TSC22D3,NANP,TXNL4A,CISH,CXCR6,GNA14,PAX6,ZNF507,STAT1,PRDX2,DPP4,HEXIM1,EIF2S1,UGP2,LMO3,LMBRD2,MRPS33,IL3,CHRM1,MSX1,KCTD9,RPN1,CD151,TLR6,P2RY11,DLG1,SDC4,CD79B,WASL,DYNLT3,ZBED4,OR4N4,SP4,BVES,RAB14,TMCC1,REP15,GOLGA7,NDUFB7,ZNF526,NDUFV2,NEK2,PC,RAB5A,TMEM31,PTN,SSBP1,F10,KCNA3,MAP1LC3A,OR10G2,RAB13,RNF26,PATE2,MRPL51,CDK5,GNG3,CYB5R3,PLAC8,NDC80,SNAPC5,RPP21,SFTPC,ZC3H15,DSN1,SLC25A23,ODC1,NME4,FNTB,TOB2,YIPF5,PDSS2,SLC6A4,OAF,SHMT1,SLC45A3,NDUFA4,CYTL1,SYNGR4,PPFIBP1,HEXB,CALR,TRUB1,SNAI2,THBS3,DRG2,PKIG,MOBP,ADCY2,TSG101,MAMDC2,RPL10L,COG1,SCYL2,MBLAC2,ALG2,PHKA1,PRRG1,SAT2,GPNMB,IRF6,RAF1,DNAJC10,RGMA,OR51A4,ZNF330,DET1,KLHL7,MCHR2,CSTB,GTF3C3,RNF14,EIF4A3,DDX5,RAP2C,LAMTOR1,ADNP,CYP17A1,FOXP2,UBE2F,TPSG1,UBN1,CYTH1,CCDC71,SLC1A1,PDE9A,RPS5,CCHCR1,SNAPC2,SLC22A12,BAALC,PHAX,FKBP10,GPX4,EXOC1,RIMKLA,FGF12,SEC62,RHCE,LY6G6C,ANGPTL2,TNNT2,GOLPH3L,COMT,TESK2,STK11,SEC61A2,RPS27L,ELAVL4,SNRPD3,ZNF175,LAMTOR3,GPSM3,TP53INP2,LITAF,ARFGAP3,ARL4A,MEF2C,DRAP1,LRRC4,RPRM,PLAA,BAP1,DOHH,FUT1,IL1B,GPR26,TMEM209,GLYAT,GFI1,CD1D,PLN,FCF1,MRPL52,E2F4,CDC42EP2,PPM1G,DEDD,BOLA3,FLRT2,CSNK2B,YIPF4,OR4K17,TMUB2,RHOB,MAX,HOXB1,NRSN1,GLRA1,G2E3,RPL3,MTG1,QPCTL,RBM18,TOPBP1,PROM1,MRPS18A,C1QL3,VMO1,TRIM11,GNAI2,CDC123,UCK1,KCNMB1,TRMT1L,GABARAPL1,FAM118B,ARL10,MYCT1,CBX5,PEX5L,TM9SF1,COMMD2,MAGOHB,EGFL8,ARL15,ILVBL,AZI2,NUDT5,NDUFA12,KCNMB2,GTPBP1,RPS11,NAE1,GSTK1,KATNAL1,TXNRD1,TNFRSF14,TMOD1,TMEM199,GZMK,FBP1,STX12,RP2,CENPP,NLRP1,CNPPD1,PSMA5,AOX1,B4GALT1,STARD13,TGIF2LX,CRKL,ATP1A1,DNAJC27,LRRN1,GCC1,CD1B,KDSR,ZFAND2B,DNAJB6,TAS1R2,DAD1,ZBTB2,MFN1,PLA2G12A,CAMLG,NPY,CNR1,GABRA2,PFDN4,COMMD5,SST,NICN1,RSAD2,RAB30,EFHD2,PSMA2,DNAJB2,GGT7,GRXCR1,GSTM2,NAA35,UBFD1,PPIG,NRBF2,PPP4C,PDRG1,FOLR2,SOCS3,PTPN22,HSP90AA1,CD1A,HDDC2,FNDC9,PPIH,DCUN1D5,EPO,EID1,ZNF280B,MMP21,NFKBIB,CHCHD3,RNF121,PGAM1,AP2S1,UGDH,RPS13,ACTB,MATN4,DDAH2,CPNE1,GNB4,CNTN1,ZER1,RFC2,LNX2,TYW3,SNX18,FAU,CLVS1,PSME1,CYP2F1,PNO1,KBTBD4,SMC4,OR8I2,GTF2E1,TNNC2,AK5,RAB22A,ELAVL2,OR5AP2,MOSPD1,FCHSD2,ISCU,AGAP1,UBE2E3,SLC6A12,TRIM10,PIR,UBE2M,RPF1,LDHB,RNF126,TMEM182,FOXP4,AKR7A2,AURKAIP1,TM9SF4,TCEANC2,LRRC1,NUP37,FERD3L,USP5,MXI1,ITGAV,PPP2R3A,GPR85,SLC1A3,DRD1,SMAD4,SLC22A8,FZR1,RILPL2,IL1RAP,VKORC1L1,DRAM1,SMARCA5,FAIM,ELK4,ATP1B1,BAK1,DYNC1I1,HECTD1,LGR4,FGF10,TLR2,IL6,CCDC122,PPP1R12A,GRID1,RERE,GABRB2,ARMC1,TFEB,CES5A,HSCB,SYVN1,UNC119B,TBC1D4,MORN4,GIMAP4,HPGDS,NDUFS3,OR9K2,RLN2,GOLGA5,OSBP,DNTT,PSMC1,MED21,TWSG1,OCIAD2,PAIP1,SSRP1,RIC3,DES,ARHGAP25,ZRANB2,PCDH9,LIN7B,EIF4E3,MYOZ3,TCAP,VTI1B,GLT8D2,SPATA6,ZNF575,MRPS7,CCL20,ARHGAP5,RPL35A,RSRC1,CD248,ZNF668,KLHL12,PPM1D,IDO1,SERPINI1,SLC39A3,SLC25A28,MSL2,CXCL12,FLCN,STIM1,GRPEL2,LRIF1,TMC7,FTL,TNFSF13,FLRT3,DHPS,RRN3,UTS2,GNG5,TMEM14B,NIF3L1,CYP27B1,PNOC,NTPCR,YBEY,MRPL10,IL15,ARL6IP6,TLE1,BTF3L4,HMG20A,RIMS4,NDUFA2,IFNGR1,NUP50,MOG,PLSCR4,LRRC57,OSGEP,SCN3B,NMI,PADI2,POLR2F,POMT2,NDUFB10,TMEM190,NSFL1C,SCPEP1,OGN,CHRDL1,ZCCHC17,PSMB6,IZUMO1,PIP5K1A,TRAF3IP2,TOMM20,PTGER4,DHRS7B,BAHD1,TERT,MORC4,CISD1,LANCL1,PIK3R3,MKKS,SLC35B4,KRTAP12-4,MPZ,VPS28,SRC,CD2AP,RASL10A,METTL6,OR51M1,GNG13,TUFM,IDH1,IFNA2,HMX2,CHST11,NEUROG2,MTMR6,CCDC85B,SEMA6C,LUM,ICAM3,UNC50,MED31,SH3BP5L,RPL7,YTHDF1,TUBA1A,CELF6,FCGR2A,NAA50,ENTPD3,RASGRP3,MGAT1,RCE1,RGS19,IFIT2,SECISBP2L,RAB33B,MCM3,RNF115,CDC42EP3,PAFAH1B1,SLC25A11,KCTD15,MS4A7,PDCD1,PSMD12,CCT7,CKLF,ZDHHC15,RSPH1,MAP3K12,FBP2,PPIA,TMOD3,SOX3,RPS4X,COX19,LRTOMT,NCKIPSD,DEFB121,CTSB,RPS29,SKA3,ALKBH2,LECT2,TRIM52,HNRNPA1,ACOT8,SLC16A4,POGK,NFE2,CLEC9A,IKZF2,RPL8,PGM1,HADH,NAT9,TFIP11,GABRG2,WASF3,PRKCQ,SMCHD1,B4GALT7,ZSCAN5A,CLCA1,TMEM88,TRMT11,GTF2IRD1,CD1E,MRPL40,HTRA1,KIF3B,HELLS,IKBKB,MITF,RPL13A,FAHD1,TRIM8,SYT4,WDR20,HRAS,RPP14,TAGLN2,CDK8,BSCL2,RNASEK,COX10,PHF23,ELOVL3,CYB5A,TFG,MAEL,MTX2,VLDLR,DHRS7,CRB3,CLVS2,WDR83,VAMP3,TUBB,ZFP64,COIL,FAM50B,STX10,ZNF596,SFN,MCHR1,TRAPPC10,PSPC1,GNAI3,SF3A1,CHID1,DISC1,NETO2,SMARCD3,AVPI1,SSR1,RBFOX3,LILRB1,EMP2,OVGP1,DNAJC1,HCLS1,GPX2,TRIM46,GLRB,EHHADH,TRIM63,PAQR9,IL4,TIAM1,THAP2,STBD1,FAM110B,OR7E24,LDLR,FOXP3,TMEM160,VPS4B,RHBDD3,GSTA4,PPP5C,RBM42,PCMTD1,RASGEF1C,MAP2K6,CA10,MAD2L1,LACRT,ANAPC11,SEPHS1,TOMM7,CDC16,GLTP,GNB1,INPP5E,ASB8,ORMDL1,CXCL11,GHR,MED30,SOCS4,MED9,TREML1,PYCARD,CUL2,SLC6A8,CDC42EP4,EIF3E,CTBP1,MSRB3,EXT1,ALKBH3,DDT,JUP,KLRD1,FASLG,SNX5,SLMAP,CFL2,ZMYM2,OR4N5,BUB3,EXOSC4,ZNF7,RNF41,XPNPEP1,DCAKD,PLP1,MGAT4B,CD52,CYP3A5,DCUN1D3,LMNA,PHF1,IRAK1BP1,TIMM8B,TMEM74,BLOC1S3,PHC1,TAAR6,UGT2A3,PLXNC1,GRAP,EPYC,DCP2,MED17,TMEM184C,NOB1,GEMIN7,ZBTB33,PHF12,BAG2,HP1BP3,TLCD2,TAS2R16,PACRG,IL13,EIF4E2,GRM8,UTP15,MCM8,CAMK2N2,DLAT,RMI1,CUTA,RIMS3,MT1A,CD38,ANKRD49,PNMA2,CDC40,SCN1B,SUB1,OR52W1,NDUFB5,TM2D2,NELL2,PCSK2,ARHGEF6,DCAF4,SLC39A13,CYP4F12,CPE,LRTM2,CYB5R1,MYT1L,USP2,REXO2,GPHA2,NTF4,POC1B,NXPH3,SSBP3,DEFB115,NOL7,SNX2,WFDC5,CAMK1,NSA2,TACO1,IRF2,TM4SF1,BCCIP,ERP29,PTTG1,INPP5K,NOVA1,NUDCD3,SEC63,MCAT,DRP2,DYRK1A,STC1,OR8K1,RAB31,KLHL32,SRGN,SLC25A20,TSHR,INSM2,NEUROD6,AIG1,EIF2D,EIF2AK2,LGI3,C1GALT1C1,GTPBP2,LIMD2,COPS2,TRIM27,NR4A2,NOSIP,SLC25A45,UBAC2,SFXN1,CD4,KCNF1,UBXN6,GANC,ACO1,PPTC7,PCK2,TAS2R46,OR5I1,G0S2,PRMT5,BEND6,TRA2A,SATB1,CLDN6,CAPZA1,STAC3,FAM3A,MNAT1,OR4N2,CDK5RAP3,FMO3,TNFSF10,NEK9,IRF2BP1,CSE1L,UBE2B,ACHE,GUK1,STX1A,AGAP2,FBXO3,CCAR1,NTRK3,PICK1,BOLA1,PAQR4,GGCX,ELOF1,RNF146,SAP30L,FAM76B,SNAP23,PDIA2,NEO1,PCCB,HSD17B3,ESAM,NXT1,SLC35C1,ANKRD50,RLN3,RFC5,JRKL,IDH3A,MED13L,NSDHL,TMEM97,MADCAM1,POU3F4,MFSD6,ASRGL1,PSMC4,MPST,RPL17,UBL4A,GKAP1,HECTD3,PI15,FGL2,FABP12,HDAC5,VAC14,SLC25A42,CLIP3,CBLN3,CRYGA,GRIA1,YES1,GAPDH,ATP6V1G2,RAB6B,MMP14,MRPS35,MRAS,MRPL41,DDI1,COX17,RAB28,FAM168B,ELK1,MDH1,CYP1B1,NCALD,ANGPT1,KCNK17,COPS4,KLHL23,HSDL1,IL12B,ACOT6,WDR6,DEFB124,INSIG2,LHB,CBL,DCLRE1C,OR2J3,OR10G3,G3BP2,ZNF574,EXOSC8,KDM2A,KLHDC8A,POLD2,SUMO1,IFT52,FADS2,F7,ACOX1,PIK3R1,PRPF18,IGSF21,CDK2AP2,MAPRE2,FGF7,EPHA2,CAV3,UCK2,LMBRD1,SRSF1,COX6B1,DIO3,SLC31A1,ITGA2,PSKH1,STX16,FKBP4,SMURF1,EIF5A2,PI3,PMP2,DPPA2,UBE2N,ANO3,PRR19,CTRB2,NGDN,CCL1,PFDN1,LIN7C,SSR3,NCSTN,ANXA7,SGMS2,TAF2,NKX6-2,P2RY10,GPR22,SLC38A2,HS3ST5,PLAC9,ADRB2,SLC6A1,TLR4,GPN2,GPT,SRSF12,QSER1,MYO1B,SLC2A1,PAK1IP1,CBX7,COL3A1,VAMP1,ADRA1A,TNNI1,CX3CL1,FGF22,PSMB2,CTTNBP2NL,VDR,IL5,PTGDS,CHCHD1,ARMC6,SIKE1,NDN,TBC1D5,DBH,CLRN1,SNX3,GOSR1,IGF2BP1,RUVBL2,NCOA5,MMAA,PPIC,LPAR6,GNAQ,POLR2C,NFE2L2,RAD1,DBNDD1,GIPC3,NGRN,CCDC167,SMAD2,USP46,PITPNB,CD80,UBTD2,HNRNPL,IREB2,EMX1,PKIB,TAF11,CNOT7,ADRM1,RABIF,CH25H,OR2F1,HPS6,KCNH8,TCP1,CRMP1,CDC5L,LGI1,SLC35A5,TMEM19,CFDP1,DUSP9,IFNK,SIGMAR1,ATP2B4,CXCL9,MRPL17,RBPJ,UQCRC2,MRPL33,RNF152,LRRTM1,EGLN2,EDEM3,TPPP2,KLHL28,LRAT,EDDM3B,ISOC1,ZDHHC8,MCPH1,NKRF,RETN,HSP90B1,TCOF1,RPS15,ASB1,VIPR1,QRSL1,FBXL3,PTGES3,RGS10,GATAD1,ACTN4,CYP7A1,GINS4,PRRT1,ABCE1,DIRAS1,SDS,ADH1A,DCK,EAF2,ITM2A,NUDT4,MCM6,RPS24,DCUN1D1,DEFB129,SPOP,CYB5R4,TRIM22,AMACR,NR0B1,MRPL36,TIFA,TPRA1,SASH3,B2M,SLC15A2,CASP4,ACVR1,DCTN6,VDAC2,IFT57,MYH1,LYZL4,PLEKHO2,SCAMP5,CST3,ICA1,YWHAG,BCL2L1,TNFRSF9,KCNB1,NOP16,ZNF32,DMAP1,LRRC8C,PPP1CC,PAQR8,OR4E2,BAZ1B,PEX26,OR7D4,PPIL3,ZCCHC7,DPAGT1,CTSA,LPCAT3,GPR83,KCNIP2,SERTAD1,ZHX1,HNMT,FA2H,ERRFI1,MRPS26,PHF7,HMGB1,CKB,THAP6,TUBA1B,ARF1,EIF2B2,ZMYM6,GNG11,BTBD10,ZBTB26,LRRC14,EMILIN1,PRDX3,PDCD5,COX7B,CDC42SE1,BGLAP,SDHC,RGS1,ASB11,FAM83A,NOL12,RHOG,TTR,SEC61A1,GAD2,RSBN1L,METTL18,SMUG1,SVIP,ASCC1,CDH7,ZNF770,TPD52L1,DUSP18,MAEA,FBLN5,LYRM2,FOXD3,EID2,ZNF345,KIAA1958,CXCL10,DICER1,MAGEB1,SLC6A7,IL21,RPL19,ZNF362,FGF16,HBM,POU5F1,MSN,RNASE4,SAP30,DDIT4L,SLITRK5,GLIPR2,SPCS1,TDP1,MID1IP1,SERINC1,SNRNP70,PLEKHF2,LAMTOR2,SLC41A1,PNRC1,UCP2,TMEM106B,UBE2I,MED29,MFAP1,MXD1,MAP3K3,FHIT,ARL11,EZH1,ARGLU1,RNF7,MRPL16,TECR,FGR,MRPL12,RCHY1,SPHK2,ZDHHC24,ARF6,PPT1,B3GALT2,DOK5,SEC22A,MAP2K3,DCTN4,RPL7A,CXXC1,LSM12,FIG4,ASPM,EFNA5,CBFB,ZC3H14,TADA1,CETN2,ZC4H2,PITHD1,SMARCE1,LEP,SH3BP4,RIT2,CACNG3,IFNA13,OR4B1,PDE6D,PDZK1IP1,OR5K1,S100B,TNIK,LRFN3,UBE3A,CCL24,SNRPD1,ALCAM,JUNB,PTPN5,TIMM17A,SMAD9,RELL1,RNF182,LIPA,MCCD1,SLC39A10,HM13,BCAS4,TCEA1,PGAP3,LCN15,MB21D2,VCPIP1,SRP72,DDIT3,SLITRK1,CACNB2,HCFC1R1,RPL28,EDEM2,ARFGAP1,PIGC,STK38L,MVD,CYP4F22,PREP,CDC26,SHC3,SPATA4,CMTM7,CA12,SLC7A1,TBC1D16,FMOD,ADRB3,RAB11B,ARL6,STX5,CCND3,IRF4,CSRP1,LEMD3,HSDL2,LYPLAL1,OPRL1,SMG5,RNF139,ABCF1,DUS4L,PLP2,DYNLL1,HINT1,TNPO2,PYCR1,THOC6,CCL11,RXFP2,RAB9A,RPAP3,MARCKSL1,SLA2,SDR16C5,IFNAR1,GPR37,ESD,CDKN2D,ATP6V1D,VWF,CDK17,PSMB10,ART5,TMEM39A,VPS39,FAM174A,MYLIP,SART3,PTPRZ1,IFI16,OR5AN1,CLP1,CLPX,INA,ATG3,CFTR,OR4M1,BMPR1B,HS3ST1,TULP3,MPP1,PSMD1,BARX2,RANBP10,MED27,SRM,ADH1B,BLVRA,CRYBA4,RAB32,PITPNA,FOXC2,CRYZ,PCBP4,MLH3,APOBEC3B,FAM193B,SEC14L5,RPL4,SUV39H1,RGL1,DYNLRB2,CKS1B,HBP1,RWDD1,SLC25A3,COPE,RBM41,PRKCB,IRF2BPL,DCTN3,LSM5,HCFC2,PABPC5,GCHFR,GJB1,KRT8,PRELP,PCYT1B,CSF2,SKP1,CHCHD2,IZUMO2,ZNF200,TPST1,AGGF1,LCP1,HNRNPH3,HDAC11,SIGLEC5,ATG16L1,TP53TG5,DIRAS3,TTLL10,STAP1,ACTR1B,HTR2A,SMARCB1,DEXI,ALG5,SUGP1,ABCC2,STARD5,FMO1,SRD5A3,CLRN2,DCAF16,GTF3C4,MMP20,REG1A,C1QL2,PLCXD3,OR4K13,DNM2,SOX9,KCNG3,CHST10,AKT2,GAB1,ITPRIPL2,PSMC5,PRSS1,APEX1,RFC4,LCN1,TLR5,TICAM1,HS3ST3A1,GPM6A,COTL1,PNPO,OR2D3,ETFA,APMAP,PRELID1,AQP3,ECD,CD59,VSTM4,AMELX,NEU1,PDCD1LG2,GLO1,RAB1A,VSTM2L,FBXO31,MAP1B,CNOT8,PELI1,PIGK,MLN,KLF12,WDR12,TCTA,PCP2,ADD2,SOD2,SCN2B,TEF,ANKRD10,ZNF343,WBP11,ZNF436,EGR1,STARD7,CHTOP,SYPL1,GPR75,SETD3,TMEM126A,ACTL6A,FOSL2,GNPAT,ACP2,NPBWR1,RPSA,PIK3CG,RHOH,ARHGAP15,ERLIN2,HYAL2,UBE2S,RRP7A,CCDC126,RBM3,CORO1C,RACGAP1,MAGEA4,STT3A,MRGPRX1,LIPT2,HPCAL1,NAP1L5,SEMA7A,OR9I1,TRMT5,BCKDK,MED4,ZCRB1,CYB5B,DIS3L,CA14,OSBPL8,CEP57L1,ARHGAP19,TACR1,NACC2,CHRM5,EMILIN3,DRD3,NAP1L3,CEACAM5,TIMM13,XBP1,RPF2,GPR34,TBC1D1,PDLIM4,THG1L,ERCC3,GABBR1,PRSS35,FKBP2,TBCEL,CYP26A1,GMNN,TMEM87A,NUDT1,ISG20,RALB,PSMG2,CTDSPL2,ABHD2,CEP70,ARL6IP5,SNRPA1,SNN,CCDC22,KDM1A,NDFIP1,LDB1,CSRNP3,NRGN,TRAPPC3,GMDS,WNT2,BIRC5,MFSD3,VPS26B,YKT6,ANKH,ARL5B,F2,ESYT1,CAMKV,SAP30BP,HAPLN2,EDC3,AANAT,B3GALT4,DLG3,RHOU,TMEM176B,RPL22,CEBPE,ATF3,RBM5,CTLA4,RANBP1,ACSS2,DEFB1,IFRD1,PRSS37,PDLIM3,MAP1LC3B,GFM1,HOXB8,SSH3,SEC61G,CENPM,EMX2,SLC7A11,POPDC3,RETSAT,FZD6,MET,PRM1,ADIPOR1,TIMMDC1,MT1X,UBE2V1,SERPINB9,SNX11,RPLP1,PDE6A,HELT,IMP4,PHOSPHO2,OR6C4,TRAPPC2L,RFX5,MAT2A,NMRAL1,COX7B2,CMBL,CDKN1B,TAF9,MEA1,HMGN4,SCHIP1,SLC15A1,KCTD16,AHSA1,ZBTB6,PLEKHF1,TRIM62,ZNF655,TEX19,GPR78,TMEM220,ST8SIA4,TMEM168,CD200,SIAH1,LRP3,STRADB,NCK1,NETO1,PTGER2,CDR2,C9orf72,NAA30,HERC3,PSMB4,DOK6,SEMA3C,HSD17B8,IRF9,LSM4,CGRRF1,DDX39B,TRAF1,RSL24D1,SKAP2,CLK1,KCTD20,SERPINA3,RASSF4,ZMAT3,BRS3,PRPS1,HAS3,OLA1,BAD,TSPAN3,MGST3,UQCRC1,NOC4L,CRHR1,AKR1E2,GDAP1L1,SSBP2,PDCD10,LRRN4CL,RPL31,WTAP,OR4A47,DCTPP1,TMEM100,CD34,FBXL4,THAP1,UNC79,CPXM1,EID2B,PRCP,PIWIL1,TRAF3IP3,CCDC90B,TAB2,SRPK2,LDB2,YPEL4,GADD45G,RNASE9,RPA2,TMEM107,TNFSF15,SLC6A2,AIP,CD40,CRY1,NOG,ARFGEF1,TLR8,PMPCA,PYCR2,TNFSF8,CDIPT,ZNF428,PDE2A,CDK7,SIN3A,PSMD7,SCAND1,PLAC1,RAB6A,CTTNBP2,RGN,FKBPL,CYP4V2,APLNR,CNPY3,NCAPG2,SRI,PSMD3,DTWD2,GPR160,POLR1D,RNF10,OR51E2,GP9,KRTAP8-1,POLE3,OR4D5,TEX261,ZDHHC16,MDFI,PPP1R11,RAP2A,MSH6,P2RY4,FBXW4,CD209,ST3GAL2,TAS2R7,IL2RB,PTGFR,IP6K1,SLC25A24,GK5,SSNA1,GLCE,STAR,TRIP4,RPL10,PDCL,SUPT5H,CRYBA1,MPV17L2,WDR45,THAP8,NRM,HSPA5,SERTAD2,GNA11,HSPB6,FAM20B,TICAM2,FHL3,PPWD1,GPRASP2,PQBP1,TRIM44,NR1I3,PAIP2B,LRP10,CCDC3,VAV2,BTG2,ITGB8,TMEM229B,NUFIP2,HINFP,GNB3,DPEP3,TMEM183A,BTG3,OR1M1,CD9,RUSC2,GRPR,IGFBP3,GADD45A,RBMS2,TGFB2,SLC25A27,VPS54,S100A11,ATG9A,ZNF622,THOC3,PIGA,GLOD4,MX1,BOLL,SAP18,EXOC3,TMEM81,CAP2,SLC22A6,TIA1,SPG21,DDR1,EIF1AX,HSPD1,RNASEH2C,PNPLA4,PIAS1,NPC2,TMEM115,PARD6A,TCEA2,LRRC28,CDC23,MBD3,ELFN1,DMPK,SYNGR3,TANK,BRAP,MPG,RDH11,PIH1D1,KCTD3,GALC,ELFN2,RP9,OR5M9,HAUS2,SSPN,CNPY1,GNGT2,LRRC8A,NKAP,LBX1,SNRPE,RRAGB,GRIK1,DLGAP4,CMA1,ANXA4,RASL12,IL18BP,GALNT2,GORASP2,THUMPD1,GMPS,TTC9C,IGF1,CCR7,SNAP25,RXRG,MRPS17,SGIP1,MECR,UBE2G2,MRPL9,FEM1B,SUPT3H,UPRT,FXN,TOX4,KLRC2,RAMP3,CPNE2,TMBIM1,CYTH4,IFT172,IER3,TRIM26,NUCKS1,CENPL,OR8B4,TMEM165,KLHL25,SULT1B1,RPE,SLU7,MFAP3L,PTP4A2,FAM3C,IRF7,PRR13,SLC25A5,OAZ1,TOPORS,LYZ,WSB1,MACROD1,ADCK1,CYBRD1,ZNF518B,FAM151B,SLC35E4,FAM136A,MGMT,TRAPPC6A,MDC1,ITM2B,MTCH2,SP1,IMPA2,TRAM1,TADA3,UBA52,ECHDC1,AP1M1,FUNDC1,SPRY1,RPS10,CLDND1,ETNK2,CCDC106,TRAF6,KRIT1,VPS72,KCND3,FUBP3,ROCK2,TKTL1,GIN1,RPL18,DUSP3,SUCLG2,PDE7A,KIF3C,CIAO1,ATP8A1,VPS18,GHRL,NAA16,GJC1,SLC12A2,RUNX1,RPS20,SCML1,ZFAND6,MED10,TYMS,TAPT1,SRFBP1,ARHGAP12,PFKFB2,EIF5B,ACER3,MREG,DIRAS2,YTHDF2,PDE12,ANKRD6,FAM161A,LMO2,FKBP1B,EDA2R,LCORL,OR13A1,MAGEC2,PSEN1,KCTD17,CLEC6A,RASSF8,SSBP4,TLCD1,AQP11,RBP2,IVNS1ABP,PIK3CA,FAM83B,SNRNP40,JAKMIP2,PSMC3,CDH11,TMEM185A,PAIP2,NDUFS2,AP1S2,LY96,TMEM47,MAD2L1BP,AKR1B1,TAB1,SF3B1,APEX2,ADORA3,ZBTB39,RBM27,CPT1B,CNN3,ANKMY2,PIK3AP1,XAF1,LST1,COX6C,PICALM,VTA1,RPIA,COCH,FEM1C,NUDT2,ATP1A3,GH1,PEBP4,BAX,PSD2,CRTC2,TMEM38B,TSPAN15,NPM3,TRPC1,ELMO2,LYPD6,BCL9,ASPA,DR1,CBX3,GTPBP8,HS2ST1,MIS12,GABRA1,PRNP,HSD17B10,CAND1,TMEM89,TPPP3,ZNF263,SNX10,CA2,USP6NL,MTDH,SGTA,TMED9,E4F1,GSTCD,GTF2F1,DLST,SSX2IP,BCL6,PRL,MPPED2,CDC7,SLC19A3,OLR1,NDST3,FBXO8,MGAT4A,RBBP8,SGMS1,MRPS34,CYP2C9,IGSF11,DUSP21,ATAD1,TRIM45,CDC20,WDR5B,ZDHHC4,XRCC5,TIMP4,ACCS,SNRPG,TBC1D25,PEX13,AIPL1,FHOD3,SLC35B3,NHEJ1,WDR11,TYROBP,SEC13,IL2,TNFAIP8L1,VMAC,NBN,CD81,ELK3,CRISP1,DPH3,LRRC40,MT1E,UBE2E2,FSTL1,POLDIP3,POLR2L,RHOBTB3,HGS,DBR1,TAS2R13,RNF133,TMEM170A,COX6B2,PRKRA,TSPAN17,WDSUB1,GNRH1,ZNF451,PRKCE,RPL26L1,PHF13,CGGBP1,FOXA3,KLHL1,SESTD1,CARTPT,BANF1,ABHD12,NF2,PARP2,GGH,TNF,IL17F,PPAT,CYGB,NUDT9,SUMO2,TFB1M,SNRPB2,LZTFL1,KLF3,CHRAC1,CCR4,OIP5,CORO6,TRIM29,RB1,PNMA3,DPH5,FAM53C,MCL1,HCAR1,TMEM127,GSTA2,HFE,GPR35,DDAH1,NDUFA1,PAQR3,CREBZF,TRIM36,NT5DC1,MRPS18C,PROK1,JAK2,CBLN1,STK3,COMMD9,HSPB2,LY6H,LILRA2,TNKS2,PTP4A3,PLSCR1,DCAF12L2,AKR1C1,MRPS11,CSNK1G3,RAB39B,PRND,CPLX2,HUWE1,ABHD10,CNTROB,FTSJ1,PMAIP1,TTPAL,UBE2L3,CCIN,MEPCE,EIF3G,CYP3A43,SPEM1,PDE4B,B4GALT4,CAV1,TCEAL8,LXN,YIPF3,RPS2,RGL2,ITGB5,TRIM34,NDUFC2,NINJ1,ICOS,BLCAP,ZNF511,EHD4,CEND1,FAM81A,SLC25A1,HNRNPF,STAMBP,HOMER3,CXCR3,MAGEB10,PCGF6,GRM1,OR4K2,SPATA2,ADORA1,SLCO3A1,SHPRH,KCNJ10,TAF1D,MAGED2,GJA1,SURF2,SLC29A1,AASDHPPT,REEP4,RNF222,TM4SF20,CCNA2,CAPN2,LSM14A,SLC8A1,OR8H3,ABHD8,ICAM2,STARD3NL,YWHAZ,TM4SF18,TNR,OR6X1,BOK,PLCB1,GPC1,GPR17,PRSS23,ZNHIT6,ARL2BP,ING2,FRZB,SPP1,TSR2,CHRM3,DMTF1,PLG,DLK2,CDK12,PSMB7,FBXW7,TNFAIP6,EPHA4,CTU1,KCNJ2,ARL4D,TXNDC17,CITED1,LIAS,CPLX3,TNNI3K,GCLC,PSMD10,NPY1R,OR4F6,CRYBB3,FOXS1,PTRH2,TAS2R5,ACTR2,ACP6,SYNJ2BP,TMEM164,APLN,TMCC2,ZNF609,SLCO1A2,KCNK10,SRP14,NUS1,TMEM106C,PLEKHA8,KRT7,WDR3,GJB2,MANSC1,ISCA2,RABL3,UPF3B,ZNF576,GCA,PPP1CB,TRAM2,CHST1,MPV17,EHD1,RFXANK,TRAM1L1,SESN2,PLAGL1,PAPOLB,KLHL15,CLDN8,ADAMTS1,CXCL14,TUSC3,SPRR1B,RPL6,BNIP3L,DDX42,SLC7A14,CYB561D2,GMPPA,PPP1R16A,MT2A,ATP1A2,PXMP2,CXCR4,HSPA14,NPY5R,POLR3B,HAND2,PGR,BRD9,KCNH1,KIAA1191,CCL17,PAFAH1B2,GTF2F2,BICD2,SERPINA5,CREB1,RNF122,KIAA0408,RBM12,RAN,RPP25,SQSTM1,GLIPR1,FMO2,TMEM177,HNRNPA2B1,RCBTB1,GGCT,ATP6V1C1,FANCG,OR2A25,STX6,PLA2G15,RFTN2,TPPP,RB1CC1,CAPZA2,SLC35E1,CCL8,YPEL5,PPID,CLDN22,EGLN3,FOS,DYRK2,MRPS28,RIOK2,OAT,POMP,RPL26,OS9,NFKB1,HNRNPK,PAFAH1B3,PRKAG1,LHFPL2,ACAP2,SCD5,TNRC6C,SPTBN1,TOMM40L,EIF3J,FERMT2,GIMAP2,GNPNAT1,UTP23,CHI3L1,RNASEL,PPDPF,TNFSF18,DNAJC8,RAB33A,CRYGD,FAM107A,RNF167,OPHN1,SUMO3,CCR3,ZNF687,OGG1,SFT2D2,CMAS,RAB23,PTGER1,CBLN4,RHOJ,WWP1,TMEM50B,JUN,IFNG,S100A8,HIRA,CD47,SLC6A11,RAB37,FOLR1,CAV2,CSTF2T,FBXO25,PSRC1,IFI35,C1QL1,TIMM10,STK38,AP1AR,PNP,RAB5C,PCDH19,EIF4B,MRTO4,PTHLH,SLC25A4,SMAD3,PPP2R1A,ELMOD1,MLF2,PLEKHJ1,TIMP1,DERL2,TXNL1,TMEM59,IL6ST,RPL23A,LYNX1,INPP4A,KCNIP3,EZH2,ARCN1,RAB9B,AMT,FN3KRP,WIF1,DYRK1B,PHYHIP,STAT6,OR10G7,ISG15,SNX24,ACADSB,BEND5,CMPK1,SNRPA,RAB2A,CTNNA1,GPIHBP1,WDR44,TRAPPC6B,VAMP2,CCNF,CRBN,CD226,VPS33A,SACM1L,B4GALT3,PDYN,ZFP1,TAF5L,MYEF2,PNPLA8,NGB,GLT8D1,UQCR11,MOV10,PCGF3,GPX5,TMEM14A,GDE1,TCEAL7,CDH8,CPSF2,MRGPRX2,GRIA2,LRRC24,LIX1,KLK5,CAB39,DDX4,TMEM91,SLC43A2,ZCCHC9,TOP3B,B3GNT2,HIGD2A,TEX12,FAM168A,ACTL6B,UBE2D1,LY6G5C,SLC4A8,SNIP1,HRH3,ABHD13,ZBTB45,RPAP2,OR5L1,RGS5,INHA,RAB1B,NDE1,RBMX2,AMY2B,CCDC65,LDHAL6B,HMBS,CD2BP2,TDRD7,SLITRK2,ORAI3,ELSPBP1,STX18,RBFOX2,FOXN2,GK2,CDKN1A,OTUD7B,PPFIA3,SDHAF2,CLIC2,MED11,AKIP1,PIWIL2,SOS2,ROGDI,PGM2L1,GYS1,SLC23A2,TMED7,RNASEH1,DNAJC3,FKTN,KLK6,SLC41A3,SERINC3,STAU1,TSN,STOML3,CDK4,NPR2,CNNM4,NR1I2,DPY30,BRCA1,ABHD4,PCDHB1,KCNK13,RBM7,TRAF2,PDHA1,ADPRH,MBD5,KCNMA1,BCL10,NOS1AP,RGS2,STMN2,NME1,DUSP19,SLC32A1,PARP11,ZNF501,CEP97,ST3GAL5,STK24,LCA5,RAC2,LRP6,MRPS21,PYROXD2,MTHFD2L,CD36,IRF3,PCMTD2,PAX9,STXBP1,KLC2,PRKAB1,DPEP1,UQCRH,DERL1,IL18,SOX2,CSNK1A1L,ST3GAL1,PHYH,FUT9,RTKN,NTN4,HOXD12,RPLP0,UBE2V2,IL10,EFNB1,SH3GLB1,THTPA,PREPL,OLFML3,TSPO2,GOLGA7B,ITGA6,CSNK1A1,COMMD8,TFE3,MT1M,DEFB114,IFNA10,SNAPC3,SNCG,BLOC1S2,SSU72,IGBP1,AKAP12,RAB40AL,DDX39A,TMSB4X,TRIM5,EIF4E,LHFPL4,CDKN2C,COX4I2,SPECC1L,NAT2,KHDC1,RINT1,OR10G9,TSPAN5,BZW2,ZBTB17,BCAP29,FABP7,CD274,EIF3K,CREB3L4,B3GALNT1,EED,ABHD14B,MRPS16,YAF2,ELP3,CIB2,TGFB3,ACSL4,MRFAP1L1,TRIM24,ZNF592,MTRF1,B9D2,EWSR1,GPX3,PROS1,TMEM204,EMP3,OSTM1,CHMP2A,CBR4,SLC19A2,VMP1,HSPA8,GMPPB,CALHM2,ADO,TES,CCDC25,LMNB1,BECN1,HTR5A,TMX3,EIF2B3,CHGA,GBE1,PAPSS2,TCF23,GPR65,SEC61B,TOM1,BCL7B,PGPEP1,F9,NKX3-1,OPRK1,GCNT3,MYO6,CYP2C18,NDUFS8,GPR137,BCS1L,SNX17,APOO,TOP1,TMEM144,NRSN2,DSTYK,AIF1L,ZC3H7A,ZBTB5,TMEM123,CIDEB,ARMC7,ATAT1,IPO8,TMSB10,GPHN,ISG20L2,HSP90AB1,POLE4,ZNF862,SYP,ATG4A,CSRNP1,FUNDC2,MRPS23,RER1,FCN2,CDKN2AIP,RGS7BP,SFRP4,TFCP2,METTL2A,CLDN1,ABHD6,CCNB1,CTDSP1,AKAP14,CRYBB2,NDUFAF4,ALKBH5,ERH,ANKRA2,ADIPOQ,LCP2,CRTAP,UHMK1,GNG2,EDEM1,VAMP5,METTL14,MAP3K11,MBL2,PTS,TOR2A,AMIGO1,JPH4,COL1A2,RMI2,SMU1,SLC35D1,R3HCC1,CSGALNACT1,SAT1,RUVBL1,SDF2L1,GTF2B,CXCL3,NKIRAS1,OAS1,GIT2,CLDN4,SLC13A5,LAMB2,RAB3D,ZNF287,TMEM184B,KDM4B,ACAT1,TRIM54,FAM98A,ACBD7,CDC42SE2,RPLP2,TGIF2,GREM2,POPDC2,GPX6,HTR1F,OR4Q3,CREBBP,PRPF19,GPAM,PDCD4,LDOC1,RDH10,E2F6,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,MRPL23,GDI2,GFM2,KLHDC8B,RNF141,ARHGAP1,DOK4,KLK9,PLA2G5,PDIA6,SDR42E1,UBR7,PRIM2,SNRNP27,CD99L2,TRIM32,SLC17A5,SLC25A31,ZNF671,UGCG,MEAF6,LYPLA1,LIG3,RPS14,TMEM219,ATP6V0B,EDF1,ZNF207,POLR3H,TMUB1,TRIM3,C1QC,FIBIN,L1CAM,TLR9,COMTD1,FNDC8,FGD2,APEH,AKT1,DLX1,DPP10,PRRC2A,RPS23,CRABP2,IL20RB,DKK3,SF3B4,CCNI,PPIL4,RAB11A,CDO1,LYAR,TOM1L2,GNRHR2,UST,PFDN5,EXOC8,RND3,CNP,NUDT3,B9D1,GSTO1,TMEM156,SOCS5,AK2,GALNT1,CCDC69,PSMA3,MRPL13,MDM2,MGP,EHBP1,SLC38A9,IL15RA,OSM,RMND1,FAM78A,PPP1R2,MIOS,ENY2,RAG1,IMMP2L,SLC35A1,DHRS4,MRPL24,MRPL50,ZNF304,SNAPIN,KLK3,SLC30A5,MYL12A,HSD11B1,CYP39A1,SWAP70,FAM8A1,NCR3,ITK,EIF4H,CHDH,GNRH2,SENP5,IDH3B,GRM2,CTNNBL1,CYP11B1,TLR3,JAKMIP1,GPAA1,ZMYND19,SLAMF9,TAAR1,CCR6,SEC14L1,ZNF319,ID4,ZNF397,APOBEC3A,XAGE5,GLUL,CNIH4,NRP1,NCKAP1,CDK5R1,CLU,KIAA0232,ATPAF2,LMO4,LTBR,OR4D11,GAL3ST1,CASK,FGFR1OP2,GABARAP,PRPSAP1,TCP11L2,GRPEL1,ELMO1,UBE2D3,ATP6V0E1,CCT2,UBE2A,ARMCX1,P2RY1,STRBP,ING1,IRF1,OR8B8,TRIM23,NAIF1,NHP2,MYH2,SNAP91,HEBP1,SLC7A9,ALKBH4,PACSIN3,PGK1,ROPN1B,VRK1,TMIGD1,DNAJC5,DYNC1I2,S100A6,CYP27A1,CDC73,UBAP1,ZYX,LHX2,MMP9,BTF3,P4HA2,JOSD1,SUPT7L,RS1,KIT,LSM3,AFTPH,OR4D9,RARRES2,CSNK2A1,PIWIL4,KPNA1,GSTO2,KBTBD2,GNG7,CTNNBIP1,ATF4,NDST1,DEFB116,TNFAIP8L2,DHRS3,CDCA3,RAB3B,SMAP2,KTI12,FGF1,HBE1,AZGP1,ABCB1,INO80C,PSME2,AZIN1,NKX3-2,TBC1D10C,CCL19,MAGOH,MLF1,GTF2E2,LBH,JAK1,TMEM215,FBXO42,ZNF24,SERPINB10,TSEN54,MEST,FZD4,MTPN,WDR77,ATP6V1G1,LYG2,MFSD6L,SYN3,ZCCHC10,MX2,GPBP1L1,AAMP,FAM199X,CLDN11,NIPA2,RABL2B,PAEP,TRAPPC1,SLC35E3,SPTAN1,RNASET2,LRP12,NPY2R,PKNOX1,ADRB1,ZDHHC14,RFX4,FRMD8,HEY2,RBM17,PCDHB8,SIX5,TRIM21,ACTA2,ARMCX2,SPR,ARFIP1,GALNT12,PPARG,NFIL3,TRIM37,HECW1,PTPN1,HNRNPC,SETD5,RMND5B,SLC25A21,RBBP7,PGS1,ARMCX5,ZNF593,PRPF4,IMPACT,AGER,CD58,FKBP14,IDH2,RAB18,CCT5,ENPP4,PSMB5,MCOLN1,SBK2,SORD,FBXO32,ANAPC2,AGK,HCRT,CAMK2N1,FGFR1,PYGM,OR4K1,SHC1,FAM89B,PEX3,RCVRN,CCDC127,CD200R1,PPP3CA,CRYGB,KCNJ11,PRMT2,TACR3,CIB3,BUD31,SRP54,TMX4,CAMK2G,CCDC47,SCFD1,TTC4,GHITM,RPL15,TUBG1,ZSCAN1,OR51S1,EIF4EBP3,WDR37,IL23A,PSMD6,DHX9,FURIN,SLC39A9,AQP4,CREBL2,TXNIP,CCL25,GNMT,UTS2R,NEK7,SPOCK1,LASP1,PHKG1,FUT8,WBP2,GTF2A1,EIF2B5,SH3GLB2,GALE,CXXC5,OSR2,ENDOD1,ANKIB1,CIRBP,APOBEC3C,GPR162,RNF187,ZMYND11,SLC7A4,ZNF513,EEF2,THRAP3,SLC25A32,EFHC1,GJA10,EXOC2,XPO1,XPO5,INTS10,SURF4,TF,CREB3,RNF103,RANGRF,THOC1,ABCC5,DNAL4,ATP2C1,FATE1,RC3H2,NUBP2,PFDN6,LDHA,UBXN10,PCDHA5,SLC20A2,GSK3A,PRCC,ST13,RASGRP2,LPXN,DFFA,IL34,RAP1A,UCKL1,ACAA2,WWP2,RABAC1,FBXO30,TIGD7,POLR2I,CD2,TRMT6,PTCRA,CXCR1,NEDD8,HBB,FGF17,KCND2,CCL21,NDUFA5,OXNAD1,RBM23,TMED1,HEXA,ADAT1,OCEL1,BRI3,CDKL2,CHRNA7,KIF1C,GAS8,CD3G,BRMS1,PAOX,IPP,NQO1,SPATA2L,TBCE,TAC1,OPA3,NPVF,LMBR1L,IGFBP4,AKR1C2,HADHA,LEAP2,DHX16,TRA2B,SOX21,NUDT16,OR6M1,KCNA2,HSPB1,B4GALT6,LHFPL1,HSPE1,CLDN14,ZKSCAN1,STAMBPL1,SIPA1L1,PGBD2,SERPINH1,RPL37A,RPRML,MSX2,SNAI3,CDC37L1,PELI3,KRR1,NLE1,EIF1AD,NDUFB8,APH1A,ISYNA1,CXCL1,XPOT,FRA10AC1,PDIA3,WNT7A,STX17,LEPR,SFTPD,CLEC12B,RAB8B,CTNNB1,CYP2D6,INTS12,SOCS2,ESR2,DCAF5,CDK6,CWF19L1,ADCY3,SNRPD2,SLPI,CERK,USP39,ZNF174,USP38,SYNGR1,LSM6,RTP4,FGF13,PRKX,PROX1,ENPEP,NAB1,SOST,TCP11L1,SV2B,HPCA,OR2A2,EIF4EBP2,SIVA1,GFOD1,SNAPC1,SNTA1,NDUFAF2,GPR37L1,SPRED1,H19,MAK16,ALDH1L1,TSSC4,POLL,NONO,SIRT7,FYTTD1,IQSEC1,NOL4,TAPBPL,RRAGA,ETV6,RAP2B,ABHD16B,TNFAIP3,TRAF7,MMACHC,MTMR12,DUOXA2,NOP58,SPATS2L,AKR1A1,NFE2L1,RBCK1,MRPS25,PGAP2,COA4,CTSD,FABP5,MRGPRX4,SCAMP2,OR52M1,NUP107,SPEF1,PRKD3,CYP4F8,SLC5A6,DEK,NLGN2,PPIB,CDKN3,BPGM,CD164,FCAR,NPTN,CCDC42,CYC1,POU1F1,ID1,PTDSS1,ENTPD4,ARMC8,SLC35A2,DEGS1,CRYBA2,INPPL1,KIF2A,MIA2,BACH1,AP3S2,MPHOSPH10,TMEM33,S100PBP,MRPL47,KLF10,FAF2,BMPR1A,RHCG,ARHGAP21,SCG2,LCN6,SETD4,OTUD6B,CCND1,OR2W1,RPGRIP1L,ACOT13,TMED3,WFDC13,COX7A1,FBXO9,ANP32B,CHST9,CPT2,NDNF,PWP2,MTAP,RAB3C,CACYBP,CTSK,CETN3,URM1,NFYA,FAM200A,S100A10,STX8,BATF,TOLLIP,TGFB1I1,DUSP1,OR10A7,SERTAD3,MT3,EIF1B,PML,GABARAPL2,DNASE1L1,PSMA4,TAX1BP3,ZNF790,RDH12,CALY,GABPB1,ARF4,TXN,MAF1,RPS12,CYB5D2,ZBED3,DAG1,MTHFS,DUSP6,PPIF,SETD7,TSEN34,FTSJ3,GSTM3,SYNDIG1,TOX,PTRHD1,RWDD4,KPNA6,IRF8,BET1,CYB561,FCER1G,SLC25A46,TMED4,TBC1D17,HEXIM2,HSD17B1,PRDX6,AP2M1,TAX1BP1,KIN,TP53,CRELD1,NFKBIL1,INMT,TRAFD1,TRIM35,PKIA,PPM1B,MGST2,STX7,SENP8,GADD45B,HBA1,GPC4,MZT2B,NECAP1,LIMS2,OSGIN2,ACADS,PTGES,RNF128,PPP2R5A,VASH1,GAPT,TLR7,WDR55,RALA,FTHL17,F11R,ADK,G6PD,SERPINB6,SYBU,EXOC5,NAA15,CHORDC1,ZBTB16,ANAPC16,OR5B3,BRMS1L,FBXO34,HCST,DHRS1,PAPOLA,IL12A,RHAG,TLR1,OGDHL,CAPG,SAR1B,PHF21A,SLC1A2,THNSL1,COX5A,CAMP,RHBDL3,TRMT61A,GPD2,OMG,CELA3B,LBR,FBXL7,CYP11B2,STYK1,POP7,RNF181,RPRD1B,DCAF4L2,TSPO,LYPLA2,RASL11A,TBC1D19,CLSTN3,CSTA,RGS6,ALOX5AP,ELOVL6,TFPT,ZNHIT1,MECP2,NUP35,SLC25A14,PRDX4,ORAI2,SERPIND1,CHST7,CRYL1,RPL24,OLFM2,ENO1,GNPTG,ORMDL3,FOXJ3,RAD23B,UFM1,USP30,TMEM60,CHN2,HBEGF,AIF1,CALU,HAX1,EGR2,LRRC20,RPS3,OR1F1,YIF1A,OR10Q1,CA8,RAB3A,SMYD3,DDIT4,FAM91A1,LCN12,KPNA2,CTNND1,NMBR,LGALS3,MAP4,LUC7L3,HHIP,KRT222,CNTFR,NEURL2,PDP2,SMNDC1,POLR2D,SNX12,DRG1,FGF3,SRPRB,ERLEC1,CEP85,NDP,SNX33,TMEM42,USP13,SDCBP,ZHX3,ATP6V1E2,IL7,SH3BGRL,EXOSC3,SRSF4,NECAP2,PID1,MYL12B,GINS3,ENHO,GPR146,KCTD11,OPTN,APPBP2,CLEC7A,ARPC2,SPINT2,ZNF688,BCL2A1,TMEM45B,APTX,AP2A1,HRH2,MIF,RBM15B,EEF1B2,ZNF189,ZNF22,C1D,TFDP2,ACTR3B,NTNG2,LRRC8D,VIP,ETFB,WNT10B,DGCR6L,FBXO11,RBBP9,SPSB1,ZNF652,ZNF177,HSD17B11,C1QTNF1,AUH,TFRC,TTC8,IDE,ZNF267,IPCEF1,GGPS1,TSPAN11,MND1,HMGA1,OR1S1,SH2D5,UTP6,TMBIM6,CCT8,PABPC1L,LSM2,DUSP22,SOD3,ADAMTS20,GFOD2,GABRB3,MRPL49,FAM187B,YWHAH,PLCL1,MTMR2,ICAM1,DNAJC7,CD83,RPL12,UQCRQ,KCTD12,ADIPOR2,LAP3,C2CD2,EFHD1,EXTL2,RCCD1,ALPL,SLC20A1,PYGB,PDE8A,PSMB9,HOMER1,SLC4A10,FOXP1,SAMM50,KCNJ8,ENC1,SRXN1,FKBP1A,P2RY12,DNAJC30,ST3GAL4,MRPS18B,EHD3,NT5C2,DOLK,ZMAT2,SAMHD1,CRYM,PHACTR1,TPH2,KCNS1,SPRYD4,API5,RPL9,DGCR8,RNF5,TST,PAAF1,TFPI,PRKCA,BET1L,KLHL26,MMD,WRAP53,GAS2,EEF1A1,TRAPPC4,UCHL3,RPL39,OR2AT4,C2CD4C,TTC33,FAR2,SURF6,BRD3,TMEM108,DVL2,TESK1,IZUMO4,AHCYL1,ALDH1A3,ADM2,HNRNPH2,HMOX2,NPTX1,CLIC4,COX11,CARHSP1,TIMM8A,NPC1L1,KLHL9,C2CD2L,DNAJB4,TXNRD2,RAD21,RAP1B,COQ10B,POLR2G,SNX14,LAT2,FITM1,ACTR1A,ACVR1B,FAH,RPL10A,CTDSP2,SDC2,LRRC4B,GREM1,TOMM40,MPHOSPH6,FABP4,COX4I1,ANAPC4,GDPD3,ARPP19,HDAC3,NLRP2,MRPL53,RPL29,GLRA2,MAP1S,BHLHE40,PI16,SKA1,CSNK1E,GRB10,PAK6,ELOVL4,CHMP2B,RBP5,EIF3D,DNAJC4,ERVFRD-1,POLD4,MAN1A2,AKT3,CCDC92,CUL3,COX16,OR5A2,ARMCX3,MAD2L2,TMPO,UBTD1,COX6A2,POLR3GL,RBBP4,ATF1,FAS,ABCB9,CFL1,KLHL3,IRGQ,BRIX1,DPM2,RNASE6,TP53I3,RNF40,RPS26,DDX1,DAP,KDELR2,ZC3H11A,CCL27,METAP1,TMX2,HTR1A,ELF1,WSCD1,SFRP1,FGF23,GOSR2,SLCO1B3,CYP2R1,CD14,PRR5L,SLC25A39,RANBP6,G6PC3,ZNF704,EXD2,KBTBD6,FARSA,UBE2H,MANBAL,PNMA5,CD86,SLC2A8,PSENEN,OXCT1,ENO2,OR4S2,WDR82,TLR10,CD28,ZBTB25,FXYD6,NAB2,SYNGR2,CYTH2,RNF11,APOC4,TAF7,PPY,CRYAB,ROMO1,GNL1,SELL,KIAA1143,ZNF473,ATP1B3,GNB1L,LAMP3,REEP6,MATR3,CHPF,CNOT6,TNFAIP1,TMEM11,KCNAB1,CRADD,PPP1R3C,AGTRAP,SEMA5A,MCMBP,APBB3,PSMA6,PCSK9,KBTBD3,CLEC1A,AKAP1,DNAJC24,PARM1,CPSF4,LCN8,CD63,AGA,CACNB3,AGR2,TTC23,PCBD1,NLGN1,TMEM174,MORF4L1,TNFAIP8L3,SLC48A1,CDC42,SLC38A1,BACE1,DUSP10,CLN8,ACO2,VPS16,SYK,SLC25A26,FTH1,SNX1,SLC35F1,PSEN2,CCM2,ALB,PIWIL3,IL2RG,MYC,LILRB4,TMEM50A,SMG8,CD40LG,FEM1A,EEF1E1,CMTM6,VPS26A,CCL28,MKLN1,RAB35,KCTD10,MAB21L1,SHISA2,PPP1R8,OR5V1,GPR173,PSMG3,TOP2B,TIRAP,MYL6,GEMIN8,RPS9,SEC23A,TUSC2,SLC6A3,CASC3,TCF21,CALML5,PNMA1,VAPB,SP2,HEBP2,GNPDA2,TMOD2,TM4SF19,CRAT,NAPA,NOTCH2,SOBP,PTPN11,DECR2,AVL9,IQCK,TP53INP1,VEGFA,FAF1,REN,CCR1,SMPD2,NCBP2,SOD1,TBC1D13,ATXN10,ASTN1,DTWD1,DRGX,SHOC2,HDHD3,DDRGK1,RPL32,PSMA1,AK3,CLCN6,HMGCS1,SLC25A12,HARBI1,TMED5,USP16,PFDN2,LTB,TCEAL1,TRIM68,ETF1,LRRC8B,TAF10,PRDX1,FAM53B,PREB,TUSC1,NPW,NFKBIA,ATG7,RNF34,ACBD6,COPS7B,DENND2D,KLF4,OR4D2,OR10A6,ACP5,SERPINC1,HLF,TMEM59L,EGFL7,ATP6V1A,SLC7A8,RFC3,FBXO22,REG1B,GPM6B,DHRS13,PARL,GTDC1,LRRC61,UBIAD1,POLR2B,TSNAX,TEX264,SNRK,GSTA1,UBLCP1,SRSF2,SERPINB1,TRAK2,ST7,AVPR1B,KLF9,STUB1,PIP4K2C,ACVR1C,NKIRAS2,FAM181B,TMEM41A,IL1R2,SLC22A17,TNKS,ST8SIA5,CYP1A1,PLS3,BST2,PPP2R2C,STK4,VRTN,HINT3,SLC25A10,RPRD1A,GTF2H5,DDX50,SYNCRIP,SLC35F2,TRMT112,VGLL2,DIO1,SLC16A10,CLDN9,PRICKLE2,RNF148,MSTN,RPL27,PPP1R1A,MTF1,FAM83C,ABCG2,LTA,MRPS9,SPSB3,TOR1B,MNS1,POLB,POLA2,UBASH3B,CCNH,SEMG2,KIAA0513,IFNB1,BTN2A2,UBL5,CSH1,USP3,CAPN1,ASZ1,METTL22,CYP2C8,TNFRSF1B,CDNF,CEBPG,TGFBR2,SPIN3,RPL23,CLLU1,STOM,CTTN,HP,SEMA4C,SLC2A3,RABGGTB,FBXO7,RCL1,SF3B5,IL2RA,PPAN,SPC24,SMAD1,AQP2,CLEC18A,ZNRF1,CHST13,PPP2CB,FKBP8,GABPA,KLHL24,PRSS12,PPP3R2,TIMP3,MPDU1,VAMP8,TMEM70,TTL,PMM2,PRMT6,EP300,ADAMTS10,PEA15,RNF8,APOBEC3F,PLCB2,MAP2K1,HSD17B6,TMEM167B,COPS5,STAT5A,PRDM4,FEZ1,EIF4A2,OTX2,MAGEH1,LRRC3B,FPGT,SOSTDC1,ELOVL1,SSR2,MORC2,SNRPB,TPM3,EFNA3,PTPN4,CHRNB2,GPX7,OR10P1,RIT1,FAM43A,NLRP9,RNASE1,TMEM45A,LAMP2,IFI6,AR,OR8B12,PPM1K,CCL2,LLPH,GSTP1,CBR3,CLEC2B,SEPHS2,ADD1,KLF1,FEN1,CLPB,VDAC1,ODAM,APOBEC3H,LANCL2,GLRX2,PRKACB,ASB7,ZNF326,PLEKHO1,MYBL2,ERAS,GSTM5,OTOS,CNOT2,CRHBP,GPR176,PKP4,CLDN12,ELF5,CCNY,CHKB,FCGR1A,VGLL4,DNAJC19,SCML2,MTM1,BIRC2,FCGR2B,IFIH1,NUDT7,CER1,POLR1B,SIAH2,CHCHD6,HOXC4,UPK1A,RFXAP,EPS8,SS18,MRPL22,CDCA7L,UMPS,CD1C,UBP1,MAVS,KLHL22,CHMP4C,CEP19,SOX14,PDAP1,CX3CR1,SLCO2B1,IGF1R,FAM177A1,DCTD,SCNM1,MCM4,NR2E1,DROSHA,FLOT1,ORC6,THOC2,STARD4,PGGT1B,SLC38A7,OXTR,KCNC1,LAPTM4A,FBXL19,MRGPRX3,MTA2,CCDC86,SUFU,CHCHD4,CHIC2,SLC16A1,OR13C8,HINT2,NUF2,TMEM101,TPD52,ELOVL7,DBT,RAPGEF5,DAPK3,DSTN,RPS27A,PCDHB13,G3BP1,CHAC2,POP5,PSORS1C2,METTL21A,MRPL18,FGFBP1,MFSD5,OLFM3,SCG3,COMMD3,BMPR2,PPP1R1B,RND2,SHISAL2B,SCGB1D1,ILDR1,NLRP3,CCS,RASD1,IER2,CHPF2,NDUFAF3,DKK1,HERC4,NR2F6,ASNSD1,CNTN2,ZMYM3,CRIP1,PSMB1,ZNF365,BAG3,ILF2,ORC5,OXSR1,KRAS,RPS16,RRM1,RBM22,TOM1L1,KDELR1,ST6GAL1,CSGALNACT2,HENMT1,CSTF3,RPL7L1,TMEM179B,TOMM22,BFAR,UBA3,CBLL1,GLRX,TOR3A,PRR3,IL22,TAGLN3,SAV1,STAT2,EPCAM,PCDH17,SRSF7,CST11,FASTKD5,SNX22,SFXN2,TMEM117,MRPL34,NDUFB6,GNAO1,CYP21A2,NCDN,UBL3,IMP3,IRAK4,GNPDA1,KCNJ3,B3GALT1,COMMD6,AFAP1L2,TMEM30A,CCDC134,TCF19,SLC30A7,SLC6A6,TSPAN18,GANAB,RPS6KA4,BBS5,XCL1,OCRL,ZNF664,MAT2B,MLC1,PDHB,DDX46,OVOL1,DHX15,RHEB,FBXL14,TRIM15,RELL2,GPX1,RAB27A,GRAP2,RPS7,PSMD4,NPPC,LRRTM3,DAAM1,SCLT1,MRPL11,PPP2R5E,SLC11A2,SH2D1A,LMAN1,NPSR1,HSPA13,LSM10,ANKRD34B,LARP4B,PMP22,SERPINA1,STX11,OR2Y1,FBXO44,DKC1,ARPC3,LRRC3,HR,DNTTIP1,AGPAT5,PLD3,CREG2,PCYOX1L,PIK3R2,PDE1B,PCNA,DDX23,SPRED2,CDAN1,OPRM1,CTSC,TMEM126B,NDUFS6,NXT2,RHOBTB1,CD247,FZD3,IKZF5,HNRNPA0,CHST2,PGRMC1,METTL15,NEUROD2,USP8,TMEM147,LGALS8,COX8A,GPR171,DHX38,PTK7,JAGN1,SNAP29,NDUFAB1,HTRA2,RPL27A,CBLN2,NUDT12,TYW5,IL1A,BCL7C,THBD,OR4D6,PPFIA2,CNDP2,CINP,FBXW11,MOXD1,RPA3,SIT1,FDFT1,NEGR1,CKS2,RORB,CXCL13,ABHD5,EPHX1,RWDD3,TXNDC12,SDHB,GFPT1,FRRS1,ATG4C,SNRNP48,CENPW,UCN,CRLF3,INO80E,DEPDC1B,PTEN,RLIM,UAP1,THAP7,PTAR1,MGAT5B,CLDN3,ADAM21,RNF144B,ARG2,DNAJB9,GNAZ,GLRX5,RTN4,GAMT,ISX,SIAE,CNRIP1,FKRP,LPAR2,USP15,OR10A4,ELMOD2,GNG12,PABPC1,NTRK2,APOBEC3G,ZFAND2A,MME,METAP2,SEC22C,CTXN1,MAPRE1,NRN1,MUL1,SMG9,GNG10 |
| 2.159e-20 | -45.28 | mitochondrion | cellular component | GO:0005739 | 1659 | 649 | 19108 | 5553 |
MRPS18B,NAIF1,IDH3A,HSD17B8,BCL2A1,TOMM40L,FANCG,MRPL22,CYB5R3,IER3,TIMM29,EPHA4,VDAC2,CHPF,CYP1B1,ATP5MC1,COA4,TMEM160,DLAT,COX20,CSKMT,BOK,ATP5PD,AKAP1,AIFM1,NDUFB7,CYRIB,DNLZ,UQCRH,FAHD1,LIAS,COA1,CLN8,MPST,MRPS21,GK2,MRPL11,UQCC6,GFM1,ABHD4,IDE,SH3GLB1,CCNB1,DLST,MRPL34,MRPS28,STARD7,TMEM14B,MIR29A,COX7B,NDUFA5,MRPS25,MTG1,SMURF1,MRPS33,MTHFD2L,PPM1K,NDUFC2,DISC1,SLC25A11,POLDIP2,PGS1,BNIP3L,MAVS,SUCLG2,PPM1M,FATE1,ATP5PB,CBR4,EFHD1,IFI6,FBXL4,FHIT,SHC1,RAB40AL,NME4,COX7A1,NDUFAF4,PTPN1,NOA1,PYCARD,PLSCR3,FKBP8,COX19,NDUFAF6,MRPL13,BLOC1S2,BOLA3,COQ8A,MRPL18,TOMM70,RNF5,ACO2,SFXN2,NGRN,CYP1A1,COX14,SARM1,MRM2,DNAJC19,TXNRD3,CARD19,BCKDK,TRMT10B,SLC30A7,COX5A,QTRT2,NGB,PC,CCDC90B,MRPL47,NDUFA2,TRIM27,MRPS17,MT3,KLK6,MRPS7,MECR,NLRP3,TIMM17A,FKBP4,FASTKD5,MALSU1,NOS1AP,NOL7,PPP3CA,ATP5F1E,ABHD6,CCAR2,CYP2D6,MRPL53,PRDX6,ARMC1,UQCRC2,ACAA2,GLOD4,PSEN1,SHMT1,TUSC2,PPP1CC,CYC1,NDUFV2,MRPL36,CYP11B1,SLC25A4,TIMM21,MMUT,SDHC,DELE1,PHB1,FAM162A,FUNDC2,PRELID1,FMC1,ATP5F1B,NDUFS6,TOMM7,CHCHD1,TMEM126B,SMDT1,SDHB,COQ10B,HDHD5,SLC25A32,FBXW7,NDUFAB1,GPD2,GK5,SELENOO,TRIM34,ESR2,STARD13,MFN1,PMAIP1,ABCE1,MRPL51,COX6B2,PFDN2,MRPS9,DDX1,GSTP1,GPAM,MRPL57,GJA1,UQCC2,FEN1,AK3,COX16,GRSF1,KARS1,STXBP1,PAK5,PTPMT1,PSMB4,MGARP,HSD17B10,LDHAL6B,AK2,ETFBKMT,GNPAT,IDH2,PLA2G4B,TRIM32,TOMM40,RAB29,GTPBP8,HADH,MTG2,CRY1,CRYAB,COX4I1,NDUFB10,CRAT,ABHD10,PMPCA,HSPB6,MRPS23,TWNK,HEBP2,PDE12,CEND1,MUL1,MTARC2,SLC25A5,MAPK10,CNR1,ELK1,AMT,PHB2,MRPL16,PLAAT3,FEM1A,UBIAD1,PYROXD2,IRF3,ATP5MG,BAK1,PPTC7,TUFM,CCM2,MIR29C,ATP5MC3,RSAD2,IFIH1,ATP5MK,NDUFA12,HSPE1,STAR,SOD2,GLRX2,MRPS18A,PRDX3,MIR17,HSP90AB1,MPG,ACSS2,COX6C,MRPS18C,METTL15,ARMCX1,LDHB,ZBTB6,OGG1,COX11,SDHAF1,VPS54,SLC39A9,UBA52,HSCB,CMC4,MTERF2,DYNLL1,HSPD1,MAIP1,MRPL33,RAB32,CYP11B2,MPC1,SLC25A10,HSPA5,UQCRC1,ATP5F1A,DNAJC5,IFI27,TSPO,OSGEPL1,MOBP,HSDL1,TIMM13,SFXN1,GABARAPL1,MTRF1,SLC41A3,AURKAIP1,SLC25A20,CHCHD6,RPS3,DCTPP1,NDUFB8,GRPEL1,UQCC3,PDF,PNPLA8,LGALS3,MSRB3,MRPL17,FGR,NDUFA1,MTCH2,MIEF1,FAM210A,NDUFS8,RNF144B,YKT6,SLC25A46,TIMMDC1,VAMP1,CLU,TIMM8B,BRINP3,STUB1,TMEM70,OPRK1,TST,REXO2,PYCR1,CHCHD4,SESN2,IDH3B,ATAD1,RNASET2,NGDN,GLYATL3,SLC25A24,UQCRQ,TMBIM6,SLC25A23,IDH1,HSP90AA1,RNASEL,BOLA1,TYMS,CDK1,TRIM24,QRSL1,COX7B2,VDAC1,SNN,ABHD5,CYP27B1,SLC25A3,MXD1,ZDHHC8,UFL1,SLC25A51,GLUL,USP30,PIWIL4,PRKCA,NUDT2,CYB5B,AKR7A2,GFM2,CREB3L4,OAS1,CNP,XAF1,SLC25A31,MARCHF5,CHDH,NDUFB6,LIG3,RMDN3,BCS1L,AKT1,ATP5PF,FAM110B,KGD4,RGS2,TAFAZZIN,MRPL23,HSDL2,SAMM50,SSBP1,GABBR1,TERT,DMPK,MRPS11,TMEM14A,PRKCE,FXN,KLC2,MRPS26,CLIC4,ARG2,ACP6,TFB1M,FKBP10,AMACR,AZIN2,HIGD2A,SLC25A26,NDUFAF2,ATPAF2,CRYM,CLPB,MRPL40,SQSTM1,NACC2,PARL,POU5F1,DEGS1,PDE2A,PNPLA4,RPS27A,CKB,IMMP2L,MYG1,MAP1LC3B,BECN1,PABPC5,COX4I2,CLPX,HUWE1,PGR,PPIF,SLC25A21,MRPL52,S1PR4,GCLC,ROMO1,CWC15,SOD1,MPV17L2,GSK3A,PPIG,UBB,PPP3R2,SLC25A45,USP15,PSMB6,STK11,TOMM6,TIMM8A,TUSC3,ETFB,DCK,RMND1,MRPS16,G0S2,RAF1,GSTK1,TMEM177,TRAFD1,SLC11A2,NDUFB5,BCL2L1,ACADSB,ABCG2,SLC25A1,PYURF,COA5,ATP5PO,TOMM20,UQCR11,NDUFB4,MTX2,SMCP,SLC25A39,TIMM10,ACAT1,GTF3C4,AUH,MAP2K1,TXNRD2,CPT1B,ACO1,MGST3,ELK3,OXCT1,PLN,CREBZF,SLC25A14,SPMIP6,NAPG,ISCA2,CFAP91,ADSS2,STOM,ATP5IF1,MCL1,HTRA2,CHCHD3,ETFRF1,TOMM22,SLC25A28,FIS1,CPT2,ARL2BP,FBXO7,MTHFS,STAP1,MRPL24,TXNRD1,MPV17,GPX1,PGRMC1,SNAP23,STOML2,ATG9A,GHITM,DHRS4,APEX2,TMEM126A,RALA,DUSP18,GPX4,PDSS2,ACSL4,THG1L,PCCB,NFKB1,SORD,AGK,ARMCX2,ACACA,SPHK2,GRPEL2,MRPL41,PET117,SYNJ2BP,DTYMK,COX8A,MRPL9,STX17,SLC25A44,LDHA,LYRM2,COX6A2,PDHB,SRC,OAT,RAC2,TP53,TICAM1,ARGLU1,NUDT9,TAX1BP1,DUSP21,CASP4,MGME1,GPAA1,GLRX5,NDUFA4,NDUFS2,TMEM11,TRAF3IP3,TRAK2,DCAKD,ISCU,FUNDC1,PDP2,SLC25A12,TIMM23,RRM1,PFDN4,ALKBH3,TRUB1,MCAT,PTS,ETFA,PYCR2,PCK2,BAX,TACO1,LIPT2,MMADHC,MTRES1,PTRH2,MCCD1,AGPAT5,NIF3L1,MRPL50,IREB2,SDHAF2,ENY2,EXD2,MMAA,HCLS1,UCP2,TAMM41,CHCHD2,GATD3,ADCK1,CCR7,HADHA,NUDT1,APEX1,MRPL20,SDS,CYB5R1,HINT2,CYP27A1,MRPL49,SMAD5,APOO,ATP5F1D,COQ8B,CMC1,COX10,COX17,MRPS34,SLC25A42,KRAS,SLC25A27,DDIT4,TMX2,PHYKPL,PDHA1,BAD,TPPP,ACOT13,ALPL,SLC35F6,MRPL12,OGDHL,CAPN1,GLYAT,NRP1,HAX1,ARMCX3,TRMT5,CYB5A,MRPS35,PPP2R1A,TMIGD1,MRPL10,CISD1,NDUFAF3,DBT,DNAJC30,ACADS,NDUFS3,COX6B1,HIGD1C,OPA3,SDHAF4,DDAH2,CIBAR1 |
| 2.404e-20 | -45.17 | PIH1D1 (PIH1 domain containing 1) | protein interactions | 55011 | 724 | 317 | 19454 | 5460 |
LRRC40,HDAC6,OSBPL8,ECD,CRBN,EIF5A2,LDLR,SEC23A,DECR2,EIF4E2,SRP14,HDHD3,RPL12,AIFM1,POLR2I,RPL35A,RPL15,CCT5,ILF2,POLR2G,ACTR2,HSD17B10,RPL23A,TCOF1,SLC25A10,EIF3E,PTGES3,RIGI,PRDX4,RPS13,ARF4,FN3KRP,FARSA,DNAAF10,HUWE1,NONO,GMPS,PPP1CC,RPL26,ATP5F1A,SEC13,AAMDC,CTSD,XPOT,RPS12,POLR3H,MSN,RPS20,CMBL,RTRAF,METAP2,CTTN,EIF4A3,TUBA1B,ENO1,RPL22,UBE2L3,RPL13A,TXN,RAB14,LDHA,SPR,SNRPN,EEF1E1,RPS14,SF3A1,TTI2,RARS1,RPLP0,HSP90B1,LMNA,JUP,CSTB,PPM1G,POLDIP2,NHP2,SMC4,RPL4,NPM3,EIF5B,GTF2I,HNRNPA1,PDIA3,PRDX1,RPL23,MED4,HNRNPD,SKIC8,KRT8,RPLP2,ATP6V1A,RPLP1,PSMB5,PHB1,RPL9,RPL8,DHX15,CACYBP,PPIA,RPL7,NOP58,GFPT1,HSDL2,RPS11,POLR2D,GNB1L,POLR2C,NME1,RPS24,HNRNPA2B1,SLC25A5,HSPD1,IMMP2L,ANP32B,RPS27A,G3BP1,MCM3,PYCR1,PFDN6,RPS5,HSP90AA1,PFDN2,YWHAZ,POLR2F,RPS9,SNRPD1,POLR3B,SNRPD2,RAN,PELO,RPL19,USP5,MAT2B,ACTB,SIAH1,DYNLL1,TUBB,PRDX2,STARD7,PRDX3,PPP1CB,IDH3B,MYL6,SLC25A3,RTF2,MFAP1,ISOC1,ATP5PO,HADHA,NUBP2,TXNL1,SKP1,MCMBP,TPM3,GAPDH,ELOC,CSNK2A1,KARS1,MAP4,RPL10A,RPS2,RPL24,SHC1,LANCL2,MTAP,DSTN,UBE2N,RPL32,EEF1B2,SYNCRIP,SDHB,SSBP1,IAH1,MYL12A,LMAN1,MIF,RPS16,CAND1,ACTR1A,RPAP2,MTCH2,RPSA,RRM1,KBTBD4,ARPC3,CBX3,DHX9,RPL3,PSME1,NOSIP,PALM2AKAP2,CAPZA1,RPL17,PDRG1,HNRNPK,CSE1L,TMEM33,MTPN,CFL1,RPS17,SUB1,PTPN11,RPL7A,CARS1,MAT2A,SLC25A1,ATP1A1,SERPINB1,DNAJC10,BICD2,EIF3G,GLOD4,CSNK2B,RPS3,TXNDC12,GMDS,BUB3,POLR1D,SPTBN1,ACACA,PARD6A,RPRD1B,SDCBP,PRDX6,PGK1,EXOSC4,TXNDC17,RPL27,HSPA5,POLR1H,MARS1,EIF4E,RPS15,XPO1,YWHAG,PPIB,WWP2,RPL6,GSTM3,HSPB1,DDX1,ASB7,POLR2L,RPRD1A,PSME2,CCT7,LANCL1,HSP90AB1,SNRPA1,LYAR,SNRPD3,TCP1,HNRNPL,RPS10,EIF2S1,RPS7,EEF2,RPL18,RPS23,CRKL,UCK2,TUBB4B,PLS3,PDIA6,EWSR1,RPAP3,RUVBL2,ABCF1,PABPC1,CCT8,RPL31,TFG,PRPS1,CDCA7L,RPL28,RPS4X,VDAC1,RUVBL1,PSMA1,HNRNPF,PSMD1,HNRNPC,LDHB,PSMA4,SFN,HNRNPAB,MDH1,SERPINH1,POLR1B,RPS26,H2AZ2,CCT2,PRMT5,SCNM1,VDAC2,NCKAP1,APEX1,RPL10,POLR2B,FBXO22,TAGLN2,ATP5F1B,MATR3,RPL27A,TRMT112,MIA2,DDX5,SF3B1,HSPA8,XRCC5,RPS28,FLYWCH2,LYPLA2,SERPINB6,PHB2,EEF1G,UBE2D3 |
| 2.677e-20 | -45.07 | EP300 (E1A binding protein p300) | protein interactions | 2033 | 1357 | 532 | 19454 | 5460 |
WDR44,DHX15,NUP35,AGK,PSD2,MRTO4,VPS4A,HNRNPD,SIAH2,PDIA3,PIK3R1,DYRK1B,COPS4,SSRP1,SACM1L,GTF3C3,ASF1A,DHX16,ZBTB16,BAG2,SELENOP,SRSF7,SLC39A3,PCNA,HNRNPA2B1,ZYX,NEK9,SART3,BZW2,CYP2C8,RPN1,HOXB1,JUN,FAF2,PPP2R1A,VDR,BUD23,NAA15,USP5,RPF1,B4GALT3,ACTB,SNRPD1,VPS72,BRCA1,DCAF4,YWHAZ,SMARCE1,PRPF31,IRF1,NFYA,NOP53,CFDP1,SERTAD2,ARCN1,MFAP1,VPS18,KLF3,SUPT4H1,CDKN1A,ACTL6A,MDM2,CITED1,CDK9,RB1,TES,MYBL2,DECR2,ACTA2,KRR1,SMAD3,PTPN1,CNN3,EID1,SUV39H1,IRF4,GRSF1,MOV10,EGR1,TTC4,IGF1R,NKRF,SFXN1,RAB1A,FAF1,TRAPPC13,VAC14,ACTR2,SOX9,PPARA,CMPK1,VIRMA,JUNB,DEK,CEP97,TENT4A,ZBTB17,COPE,CTTN,MAPRE1,AP2A1,SMAD2,CDC73,ASCC1,CXXC1,MEF2A,PIAS1,IRF7,TCEA1,RTN4,PRKCB,IDH3A,PPM1G,RPA3,DVL2,HELLS,SHOC2,STOM,CCNA2,CDK7,NFYB,SF3A1,PCK2,TXNL4A,SUMO2,OSBP,MITF,SNRPA1,NOB1,RAB1B,HNRNPL,DBR1,WDR82,PRCC,GYS1,FUBP3,HDHD5,MAGOH,DDX1,CBL,MGMT,DRG2,CTNNB1,XPO1,RAB5C,LAMP2,IFI16,BAZ1B,DDX50,CXCL10,PRPS1,ROCK2,HNRNPF,TRIM21,EWSR1,ABCF1,CYP1B1,FBXO3,TYW5,ALKBH4,SMARCB1,EEF2,H1-3,DHX38,TRMT1L,ESR2,APEX1,CBX5,STAT2,MATR3,STAT1,PRMT5,SMU1,SCNM1,CMTR1,SURF2,IRF2,H1-1,RPS26,CMC1,ATG3,UFD1,SLC30A5,PSMD1,LDHB,HNRNPC,CREBBP,MYC,ITGAV,EEF1G,PHB2,UFL1,TRA2B,SRSF2,DDX5,SF3B1,GPHN,PEBP1,MAP2K1,SEC62,SYK,MTF1,CAND1,PLG,ALYREF,ELSPBP1,MAP4,H2AC4,TRAPPC2L,EDC3,API5,GAPDH,PPIL4,RDH11,MEPCE,CSE1L,HNRNPK,H3C1,PDE12,DHX9,CLPB,NUPR1,HBP1,EXOC3,DDX42,CBX3,TP53,STRBP,DYRK1A,CDC20,PLAGL1,STAT5A,PHAX,CSNK2B,B4GALT1,SF3B6,PSPC1,UQCRC2,RBM7,PDCD4,IGF2BP1,CCNB1,ATF4,AKT1,RAB2A,BCL6,CLU,OGDHL,HDAC3,IRF3,PML,NBN,SEPTIN6,RPL27,RBM23,DDX46,KLF4,TFB1M,HPS6,CXCL8,CGGBP1,SNX1,CCAR2,NOP58,COPS2,IGBP1,TSG101,XPO5,PHB1,DNM2,KDM2A,PSMD10,UBE2D1,DDX23,WDR11,EIF3D,TRA2A,ATG7,SAV1,PSMD3,PRPF19,CLPX,RFC3,RFC2,AP1M1,SRSF4,MCM6,GNL1,RBBP7,LASP1,G3BP1,PPAN,MEF2C,TRIP4,PLSCR1,RBPJ,EZH2,TULP3,GFPT1,E2F4,FEN1,TNPO3,SNRPB2,RBBP4,UMPS,AP2M1,FZD6,FOXP3,PELO,UBE2S,RAN,CPSF1,SP1,BLVRA,FAS,MCM4,MCM3,PROX1,RNF40,CUL3,HNF1B,G3BP2,TGFB1I1,MCMBP,HAND2,IL1A,IL1B,TSR3,HADHA,RTF2,EPO,ELF5,PPARG,MED23,IDH3B,NOP9,KLF1,AIFM1,HACD3,PSMD7,MPG,MFN1,HDAC6,NFKB1,CALR,MDC1,PRDX4,EIF3E,MSH6,OLA1,THRAP3,SERTAD1,RING1,GLUL,SLC25A10,NSDHL,EHD4,SRP72,ILF2,GABPB1,SMAD1,EEF1A1,ING1,PHF23,SMAD5,SEC63,TECR,ARMC6,LDHA,UBE2I,TRIM24,GANAB,RTRAF,PELP1,CASC3,XPOT,TADA3,TUFM,PPP1CC,GMPS,NONO,AR,RUNX1,PYCR2,CDC16,SS18,HMGB1,NUCKS1,SMC4,GTF2I,MTDH,PNO1,SLC39A9,IFRD1,PAX9,OXSR1,CDK1,JUP,ELP3,EIF3J,EID2,CCND1,ELK1,ASIC1,LYAR,PGR,POLR2L,SRSF1,DRG1,FOSL2,POLDIP3,HNRNPDL,PAX6,RERE,SATB1,PDIA6,RTCB,RPAP3,RUVBL2,TOP2B,PABPC1,AAMP,ZRANB2,MTA2,KIF2A,CRTC2,SOX2,TRAF2,SUPT5H,TOP3B,MAX,PSMD6,ANAPC2,NFKBIA,MCAT,RBM27,CHTOP,BRMS1,LDB1,ZBTB5,STAU1,EMC1,EP300,STK26,DDIT3,HSPA8,FOS,XRCC5,PYM1,RFC4,HIRA,SNRPA,KLC2,CTBP1,PAK2,PALS2,SSBP2,CDC5L,SURF6,DKC1,TMPO,RWDD1,MCL1,SFRP1,STT3A,GTF2B,EEF1B2,CDK12,SNRNP70,SMAD4,POLB,SSBP4,COPS5,CSNK2A1,PGAM1,RBM17,ZNF24,EDEM1,FKBP8,KPNA2,CDC40,DYNC1I1,ABCE1,SNIP1,NOSIP,RBP2,SESN2,IK,NFE2L2,TFRC,RPAP2,EGR2,WBP11,H2AX,PREB,RRM1,BCCIP,SRPK2,SRC,CSTF3,NR1I2,ROCK1,GABPA,ADRM1,BUB3,ING2,UBN1,ZBTB33,GCFC2,CREB1,CALU,EIF3G,UTS2,MORF4L1,SUB1,FGFR1OP2,RPF2,MARS1,HSPA5,KDM1A,CWF19L1,POLD2,ACACA,HECTD1,STAT6,PRKCA,UBE2M,WRAP53,RPRD1B,SUMO1,ING5,CAPN1 |
| 2.839e-20 | -45.01 | PHB2 (prohibitin 2) | protein interactions | 11331 | 500 | 236 | 19454 | 5460 |
MRPL17,PDHB,YKT6,AATF,PIAS1,MEF2A,DVL2,RPA3,SQSTM1,MAVS,METTL14,STOM,HSP90B1,GRM2,JUP,LMNA,MTRES1,PDCL,TIMMDC1,ATG16L1,CDK7,UQCRC1,NDN,VIRMA,UQCRQ,CCNF,CHCHD6,PTEN,DNAJC19,RALB,NDUFB10,AR,KPNA6,TUFM,HMOX2,FBXO7,ATP5F1A,HUWE1,RIGI,MDC1,PDE2A,SFXN1,FAF1,RAB1A,EMC2,IGF1R,GNG5,NDUFS3,TNFAIP8L1,RNF181,MRPL11,NDUFA2,CCDC47,FBP1,TIMM8A,MAP1LC3B,ARF6,CAV1,ZBTB2,SLC25A12,TOMM70,ATP5PD,MDM2,TFE3,HACD3,TIMM8B,PTPN1,AIFM1,DCK,POR,ATP5MG,EMC4,HDAC6,LZTFL1,RNF11,EXD2,PSMA3,HADHA,NMRAL1,HACD1,TRIM5,ATP5PO,PPARG,SLC25A3,MTX2,TIMM13,RFXANK,ACTB,TUBB,NDUFAF4,PARL,CHCHD3,CYB5R3,DCAF4,BRCA1,LMNB1,RIT1,RAB11A,CUL3,PMPCA,NDUFB7,TOMM40,TRIM37,ETFA,EMC8,PLCB1,COX8A,ZC3H7A,HINT2,EZH2,CYB5B,RAF1,CYB5R1,JUN,RAB11B,SERINC3,NDUFS8,PHB1,FOLR1,GATD3,CYB5A,ATP6V1A,MAP1LC3A,RHOG,HAX1,STOML2,HNRNPA1,MRPL40,SLC25A51,HDAC3,HSPA5,BCL6,NLE1,SSR1,WWP1,RPA2,CYC1,HECTD1,UBE2M,PRKCA,HEXIM1,CFTR,CDC42,GABRA1,DYRK1A,UQCRC2,RIC3,RC3H2,CHCHD4,SPOP,UBE2H,FGFR1OP2,NAA50,RAB2A,AKT1,KPNA2,FKBP8,MEPCE,IDH1,CLPB,MRPS18B,TFCP2,PSMC3,SLC25A24,RNF8,INSIG2,MTCH2,UBL4A,SNAP29,APOO,MYL12A,TMPO,LMAN1,COX4I1,CD274,SMIM12,TMEM70,USP15,KPNA1,COX5A,DPP4,ADRB2,STAU1,GOSR1,NDUFS2,UFL1,EP300,AKAP1,HDAC5,NLRP6,PIH1D1,CAV2,MTF1,ATP6V1C1,PTAR1,TOMM22,YIPF5,TRIM29,TAX1BP1,ATP5F1B,ESR2,LRIF1,CCDC90B,LMBR1L,VDAC2,ARMC7,ICAM1,LDHB,COX6B1,MYC,PCCB,VDAC1,USP30,KRAS,PDHA1,RAB4A,TUBB4B,NUDT19,FAM136A,EEF2,TUBA1A,ISG15,ANKRA2,UQCRH,EED,CORO1C,AGR2,NDUFB8,HSPB1,CDC23,UQCC6,CBL,RAB5C,WWP2,DDRGK1,CTNNB1 |
| 3.084e-20 | -44.93 | RIOK1 (RIO kinase 1) | protein interactions | 83732 | 552 | 255 | 19454 | 5460 |
RPS7,H1-3,TUBA1A,SUPT5H,TOP3B,RPS23,RPL18,PDHA1,TUBB4B,RTCB,ACTR1B,RUVBL2,PABPC1,CCT8,ABCF1,RPL31,HNRNPDL,RPS4X,RPL28,RUVBL1,HNRNPF,NGDN,XPO1,RPL6,IFI16,DDX50,GSTM3,MAGOH,YWHAB,DRG1,DDX1,H2BC17,ZHX1,SRSF1,RAB35,HSP90AB1,CCT7,TCP1,SUMO2,SNRPD3,LYAR,SNRPA1,EIF2S1,NOB1,RPS10,ELK4,RPL27A,TRMT112,ACAA2,EP300,DDX5,SF3B1,RPS28,PEBP1,SNRPA,MRPS7,STAU1,UFL1,SRSF2,TRA2B,HNRNPA0,SNRPB,HNRNPAB,LDHB,H2AZ2,FTSJ3,CHTOP,H1-10,CCT2,CIRBP,SF3B4,PRMT5,SMU1,CMTR1,RPL10,FBXO22,ACTR1A,RPSA,UBL4A,KBTBD4,DHX9,RPL3,EIF1AD,METTL18,H2BC14,RPL17,KPNA2,CSE1L,IMP4,HNRNPK,H3C1,GAPDH,CSNK2A1,RPL10A,RPS2,SNRNP70,RPL24,RPL32,MRPS9,SYNCRIP,CDC5L,SURF6,DKC1,RPS16,CAND1,FZR1,LUC7L3,TFIP11,TFB1M,UBE2M,RPA2,H2BC11,HNRNPH2,BAP1,MARS1,HSPA5,KDM1A,RPS15,H2BC9,RPS17,RPL7A,SMARCA5,TNFAIP3,UBE2H,IGF2BP1,LSM6,MACROH2A1,PHAX,CSNK2B,EIF2S2,ZNF330,RPS3,SUCLG2,SMURF1,RPL10L,BUB3,RPL29,PPP2R1A,RAF1,BUD23,SART3,SNRPE,RPS11,RPS24,SRSF7,HNRNPA2B1,PPAN,HSPD1,AP1M1,UBE2A,MCM6,RPS27A,SRSF4,RBBP7,G3BP1,HNRNPA1,PRDX1,PRPF19,PSMD3,RPL23,HNRNPD,MED4,RPLP2,IFIT2,PPP2CB,RPL8,DHX15,EGLN3,SPTAN1,RPL7,WDR77,H1-5,ARCN1,MED23,CFDP1,PMAIP1,CCDC86,EEIG2,G3BP2,COIL,PSMC1,MCM3,RIOK2,NOP16,RIT1,SETD7,CBR3,HSP90AA1,RPS5,RPS9,AP2M1,SNRPD2,POLR3B,FAM177A1,FAU,RPL19,SNRPB2,RPL35,RPL7L1,ACTB,RPL15,EEF1A1,MRPL11,ILF2,EMC2,RPL23A,HAPSTR1,EIF3E,MSH6,MRPL22,RPS13,LSM4,GRSF1,CRBN,PLPPR1,KRR1,RPL12,SRP14,H2AZ1,CDK7,SNRPN,RBFOX2,RPS14,RPL26L1,RARS1,HNRNPH3,RPLP0,LSM2,H2BC12,PRPF4,PNO1,RPA3,AATF,BRIX1,FBXW7,RPL4,SMC4,GTF2I,TUFM,NONO,NTAQ1,ATP5F1A,RPL26,XPOT,CDC73,RPS20,PTEN,RPS12,RTRAF,ENO1,EIF4A3,VIRMA,RPL22,RPL13A,LDHA |
| 3.315e-20 | -44.85 | WWP2 (WW domain containing E3 ubiquitin protein ligase 2) | protein interactions | 11060 | 831 | 354 | 19454 | 5460 |
MTDH,SQSTM1,DGCR8,EIF5B,RPL4,EDF1,EIF3J,RPS14,EEF1E1,RPLP0,IFRD1,P3H1,PRKRA,RTRAF,RPS20,UBE2I,PTEN,OPTN,EIF4A3,RPL22,ZNF622,RPL13A,ATP5F1A,NONO,TMEM255A,ATOSB,TXNIP,PC,HSD17B10,OLA1,RPS13,EIF3E,TOM1,THRAP3,RPL15,ILF2,RAD23B,SRP72,PWP2,SRP14,ETV6,UBP1,CAV1,TOP1,POLR2I,MPHOSPH10,HADHA,WBP2,G3BP2,TMEM127,RND2,PPP1CB,PRDX3,IL2RG,MYL6,RPL37A,CPSF1,ARF1,FAU,EIF3K,RPL19,SNRPB2,RBBP4,RPL35,OTUD7B,RFC5,FMC1,NOP16,PFDN6,RPS24,NDUFA4,PPAN,RFC3,RFC2,G3BP1,GFPT1,SF3B5,EZH2,CFAP36,TSG101,RPLP1,HP1BP3,WDR6,PHB1,NOP58,RPL7,EIF3D,TRA2A,PRPF19,CDKN1B,RPL23,UBE2D1,RHOG,PSMD10,EXOSC4,MARS1,HSPA5,UBE2K,CFTR,HEXIM1,RPRD1B,RPS3,PPP1R10,SRPK2,BUB3,RPF2,MARCHF3,EIF3G,RPL3,PDRG1,KPNA2,RPAP2,EGR2,GRAP2,SFTPC,RBM34,RNF128,GTF2B,SYNCRIP,IAH1,CDC5L,RPS16,DNAJC1,CSNK2A1,KARS1,RBM17,RPS2,RPL10A,USP15,LANCL2,SNRNP70,HSPA8,ARRDC3,RFC4,XRCC5,UBE2D3,HNRNPA0,STAU1,RPL27A,PIH1D1,SF3B4,GTF2F2,ATP6AP2,PSMD4,PCCB,FTSJ3,H1-10,CHTOP,RPAP3,RUVBL2,FBXO11,RTCB,PABPC1,TOP2B,RPL28,SOX2,KIF2A,SUPT5H,RPL18,MAGED2,LAPTM4A,POLR2L,SRSF1,EIF2S1,PAIP1,FAM98A,RHOH,LYAR,PPIB,UBE2E2,HSPB1,PPM1G,DVL2,RHOU,NF2,RARS1,UBAP1,HNRNPH3,RPL26L1,CHMP1A,RPS12,ENO1,CTTN,UBE2L3,VIRMA,RHOJ,RPL26,SMAD2,RPL23A,FAF1,TCOF1,NKRF,RIGI,DNAAF10,FARSA,POLR2G,DHRS7B,MAGEA4,NLRP1,SMAD3,RPL12,CDK9,NCBP2,ASNSD1,RPL35A,DAG1,MOV10,H2AC14,SPATS2L,ZNF688,RNF11,SUPT4H1,ACTL6A,SLC25A3,SNRPD2,POLR2F,SEC61B,RPS9,UBTD1,PRRC2A,USP5,ERH,TUBB,SMARCE1,RPS29,PFDN2,HSP90AA1,RPS5,LSM14B,RHOB,YWHAZ,PCNA,BAG2,SRSF7,SLC25A5,HNRNPA2B1,RPS27A,SSRP1,PPP2R1A,RPL29,RAF1,POLR2C,RPS11,POLR2D,SART3,EXOSC3,PRKAG1,RPLP2,RPL8,RPL9,IFIT2,SRSF10,DHX15,AGK,HNRNPA1,BABAM1,HNRNPD,MED4,SKIC8,DROSHA,RPL27,LIN7C,RASD1,LITAF,RPS15,FTSJ1,CDC42,TFB1M,LUC7L3,WWP1,SRP54,CFL1,DNAJC5,CARS1,SLC25A1,RPL7A,PDCD4,IGF2BP1,UBE2E3,DHX9,PSME1,RPL17,HNRNPK,TP53,RPSA,CAPZA2,RAC2,RPL32,ALYREF,RPS27L,ELOC,MAP4,RPL24,SHC1,SF3B1,DDX5,SMARCD3,BMPR1A,RPS28,LYPLA2,SRSF2,FXR2,EEF1G,PHB2,TOM1L2,USP6NL,NUFIP2,TRMT112,PRMT5,MIDEAS,POLR2B,RPL10,NCKAP1,TAGLN2,MATR3,STAT1,NDFIP1,BTF3,CPSF2,SNRPB,MYC,APOBEC3B,HNRNPC,H1-1,CCT2,H2AZ2,LDLRAD4,EWSR1,FAM168A,RPL31,ABCF1,RPS4X,HNRNPF,RUVBL1,TUBA1A,EEF2,RPS7,TRMT1L,SMARCB1,RPS23,HGS,PSME2,GYS1,HSP90AB1,HNRNPL,RPS10,SNRPD3,DNTTIP1,CTNNB1,DDX50,WWP2,RPL6,POU5F1,DDX1 |
| 3.745e-20 | -44.73 | HNRNPU (heterogeneous nuclear ribonucleoprotein U) | protein interactions | 3192 | 933 | 389 | 19454 | 5460 |
DHX15,MAP1LC3A,RPLP2,RPL8,RPL9,MRTO4,HNRNPD,RB1CC1,MRPS26,HNRNPA1,SSRP1,RAD21,TNF,SRSF7,MRPS11,SLC25A5,HNRNPA2B1,RPS11,SART3,RPN1,OTUD6B,ACTN4,B3GNT2,MRPL23,TUBB,ACTB,SNRPD1,RPS9,RPS5,RHOB,BRCA1,MRPL16,RPS29,MRPL57,USP39,EMC9,PGRMC1,MDM2,CDK9,MRPL24,DCUN1D1,MRPL50,PRR3,RB1,PTPN1,RPL12,KRR1,SLC35A5,MOV10,SPATS2L,MRPS18C,HUWE1,VRK1,RPL23A,FAF1,NKRF,TNFAIP8L1,FCF1,FBP1,VIRMA,NDN,RPP25L,RPS12,CCNF,AP2A1,FBXO7,IFNAR1,PIAS1,UTP23,BRIX1,MRPL17,RPA3,INPPL1,HNRNPH3,HAUS2,WTAP,DCTN4,METTL14,CDK7,SF3A1,UBA52,HSP90AB1,HNRNPL,RPS10,SUMO2,SNRPA1,DDX1,MAGOH,CTNNB1,BTF3L4,DDRGK1,BAZ1B,IFI16,LAMP2,DDX50,RPL6,WWP2,RPS4X,EWSR1,POU3F4,LSM14A,ABCF1,CCR1,RPS23,NCSTN,RPS7,TRMT1L,RPL10,APEX1,MATR3,PRMT5,SMU1,MRPL13,VDAC2,CMTR1,RPS26,H1-1,CKB,MRPS25,FBXW11,ATG3,BTF3,BAG3,SNRPB,MYC,HNRNPAB,SFN,HNRNPC,UFL1,TRA2B,EEF1G,ADRB2,DDX5,DDX39B,NGRN,EIF4B,PPT1,SYK,MTF1,ZC3H14,LMAN1,CAND1,SPPL3,FZR1,SSBP1,METAP1,MRPS9,RPL32,ALYREF,KPNA1,SHC1,RPL24,CD81,API5,GAPDH,MEPCE,RPL17,NEDD8,MRPS33,HNRNPK,DHX9,MRPL52,PSME1,STRBP,TP53,RPSA,CDC20,PSPC1,IGF2BP1,PDCD4,CDKN2AIP,UBE2H,MRPS16,CEP70,RAB2A,SMARCA5,RPL7A,WDR3,RPS15,RPL27,BAP1,PML,DYRK2,LEMD3,LUC7L3,RNF146,AGO1,NOP58,RPL7,RPLP1,HP1BP3,PHB1,AHSA1,PDCD10,BCL2L1,RPL23,DDX23,TRA2A,EIF3D,UBXN6,MRPS35,MCM6,RFC3,RFC2,G3BP1,TRIM37,RPS24,TRIP4,EZH2,NUP153,LGR4,TPD52,TPBG,RPL19,RPL35,RAN,RIT1,LMNB1,NOA1,RIOK2,RFC5,MCM4,GALE,CUL3,CUL2,GPC1,CRY1,NUP50,CCDC86,H1-5,DBT,SLC25A17,TOP1,EIF2B2,RCHY1,FBXO34,CRBN,HDAC6,APOBEC3F,CALR,RPS13,MDC1,SEM1,SERTAD1,SLC25A32,THRAP3,SEPTIN7,DLG1,GLUL,ILF2,MRPL49,SRP72,MRPL51,LBR,DDX39A,EEF1A1,RPL15,YTHDF2,RPL22,ZNF622,RPL13A,ARMC6,GSK3A,GANAB,RTRAF,PTEN,UBE2I,TRIM24,UBASH3B,EIF4A3,TADA1,IVNS1ABP,STK24,ATP5F1A,RUNX1,USP14,NONO,AR,AATF,NPM3,DGCR8,RPL4,HMGB1,SMC4,PRPF4,PNO1,RPLP0,MRPS34,LMNA,HSP90B1,GRM2,EIF3J,RPS14,MACROD1,LYAR,MAGED2,EED,LAPTM4A,SRSF1,HSPB1,IKBKB,AGR2,MRPL9,CENPW,RIOX2,RPL28,HNRNPDL,KRAS,RUVBL2,RTCB,PABPC1,RPL18,SOX2,ISG15,MAX,TOP3B,NAA16,ARFGEF1,TOM1L1,TRIM29,PSMD6,GTF2F1,NFKBIA,ICAM1,GTPBP2,MCAT,FTSJ3,H1-10,TTC33,SAP18,HNRNPA0,STAU1,HSPA8,RAB5A,EP300,SNRPA,RFC4,PIH1D1,RPL27A,RBM42,TMPO,SURF6,CDC5L,RPS16,SYNCRIP,RPS2,USP15,RPL10A,TUBG1,SNRNP70,COPS5,KDM4B,KPNA2,RPL3,MRPS18B,POC1B,SNIP1,RNF8,TFCP2,IK,RBM34,ACTR1A,UBL4A,MTCH2,MRPL47,SMURF1,BCCIP,NMI,KCTD9,MRPS21,RPL10L,MRPS28,RPS3,RRP7A,SPOP,RC3H2,RPS17,MORF4L1,PTPN11,HSPA5,MRPL40,EXOSC4,RNF113A,TMX2,HEXIM1,RPA2,WRAP53,EIF2B3,MRPL10 |
| 5.116e-20 | -44.42 | POLY (polyprotein;protein F) | protein interactions | 951475 | 510 | 239 | 19454 | 5460 |
VDAC1,KGD4,USP30,RPL28,RPS4X,ABCF1,TOP2B,PABPC1,RPL31,OAS1,MYO1B,PDHA1,TUBB4B,IRF8,HGS,RPL18,RPS23,RPS7,TRAF2,LYAR,SUMO2,RPS10,HNRNPL,EIF2S1,HSP90AB1,PEG10,SRSF1,FUBP3,IKBKB,YWHAB,DRG1,HSPB1,PPIB,PHB2,EEF1G,RFC4,PYM1,EP300,SF3B1,HSPA8,RPL27A,NDFIP1,ATP5F1B,MATR3,USP38,RPL10,DLST,GTF2F1,PRMT5,FBXW11,H1-10,H2AZ2,RPS26,HNRNPC,PSMA4,CREBBP,PCCB,HNRNPK,RBCK1,RPL17,FKBP8,ATP2B4,RPL3,PIK3CA,CD209,TNRC6C,TP53,MIF,RPS16,RPL32,SDHB,EEF1B2,H2AC4,RPL24,MAP4,RPL10A,RPS2,AREL1,TAF9,GAPDH,CD81,HSPA5,TRIM3,DLAT,RNF34,HNRNPH2,ACACA,SMYD3,AGO1,PLP2,CD2AP,EIF4H,SRC,SMURF1,TMA7,RPS3,UQCRC2,EIF2S2,IGF2BP1,RPL7A,MORF4L1,TRIM32,TIA1,EXOC5,RPS17,ETFA,G3BP1,TRIM26,LASP1,RNF26,RFC3,SSRP1,RPS27A,HNRNPA2B1,NDUFA4,SLC25A5,HSPD1,SRSF7,UBE3A,RPS24,BAG2,JAK1,CYP2C8,RPS11,DSTYK,RPL29,JUN,RPL7,IFI27,PPIA,PHB1,RPL9,PCBP4,MAP1LC3A,RNF152,RPL23,HNRNPD,RNF139,PRPF19,PRDX1,HMGA1,CRIP1,HNRNPA1,YTHDF1,FBXL4,HADHA,ATP5PO,VAPB,SLC25A3,H1-5,ACTB,TSN,RPL35,TUBB,EIF4A2,RPL19,TAF11,CHCHD3,RAN,UBE2S,FAU,SEC61B,RPS9,RPL37A,YWHAZ,CGRRF1,RPS5,RPS29,TTC4,THRAP3,TF,HSPE1,H2AC6,RPS13,VWF,TCOF1,RAB1A,LTBR,H2AC25,PC,RPL23A,SEPTIN7,SRP72,YTHDF2,AKR1C1,H2AJ,PSMB9,TOP1,ASB11,DBT,SRP14,AIFM1,RPL12,SMAD3,SPATS2L,ATP5MG,FAM133B,H2AC14,MOV10,USP8,HMGB1,FBXW7,RPL4,PDHB,EIF5B,SQSTM1,MAVS,TCEA1,MTDH,AOX1,SYVN1,RNF103,H2AC7,JUP,HNRNPH3,EEF1E1,RPS14,FTH1,RPL13A,TXN,LDHA,DEK,RPL22,CYP4F12,EIF4A3,ENO1,FBLN5,EIF2AK2,CINP,ACAT1,RPS20,TRIM27,PPIG,SMAD2,NONO,TUFM,RPL26,FBXO7,ATP5F1A |
| 5.411e-20 | -44.36 | gag-pol (Gag-Pol) | protein interactions | 155348 | 713 | 312 | 19454 | 5460 |
YWHAG,CTNNB1,PTDSS1,CST3,RPL6,RAB5C,TNNC2,DDX1,DRG1,YWHAB,IFNB1,FKBP4,PABPC1L,EED,TRAPPC10,PSME2,SIN3A,SRSF1,SWAP70,HSP90AB1,HNRNPL,SUMO3,TCP1,SUMO2,TUBA1A,RPS7,EEF2,ETFB,SMARCB1,RPL18,RPS23,PLS3,PDIA6,PABPC1,TOP2B,CDCA7L,MX2,RPS4X,IL13,IFNG,HNRNPF,PSMA2,VDAC1,RUVBL1,PSMD1,BTF3,CREBBP,LDHB,HNRNPC,GFUS,HNRNPAB,ICAM1,ZMPSTE24,SERPINH1,CCT2,SF3B4,PHKB,ANAPC2,GLRX2,PSMB6,RPL10,DES,PSMD4,MATR3,PSMD6,HDDC2,AKIP1,NUP62,TIMM10,PABPC5,TOMM22,PSMB3,PLAA,MAP2K1,IL4,HSPA8,SF3B1,DDX5,EP300,AKAP1,DDX39B,XRCC5,SAP18,HNRNPA0,OXCT1,PHB2,STAU1,EEF1G,CSNK2A1,TPM3,GAPDH,KARS1,RPS2,AKAP8L,KPNA1,IFNA2,RPL24,MCL1,SYNCRIP,ALYREF,ESD,CDC5L,H2AX,GLRX5,TP53,PSMC3,NHERF1,RPL3,DHX9,PSME1,SLC25A11,POLE4,PSMB10,IL12A,RPL17,IL12B,PSMA5,SRPRB,HNRNPK,CSE1L,KPNA2,RPS17,PHKA1,PSMB2,RPL7A,OAT,ATP1A1,IGF2BP1,EIF3G,IL15,BICD2,PSMC5,SEC61A1,CSNK2B,RPS3,CDIPT,PSMA6,SUCLG2,SRC,CTSB,PRKCE,CXCL8,SPTBN1,SUMO1,PRKCA,RPA2,HNRNPH2,PRDX6,LCP1,BANF1,IRF3,PML,HSPA5,STK38,ST8SIA4,HNRNPA1,EIF3D,PDIA3,PSMD3,PRDX1,HMGA1,LYZ,HNRNPD,RPL23,DDX23,SKIC8,PSMD10,TSG101,IL10,MAP1LC3A,DNM2,RPL9,THOC2,RPL8,PSMB5,PPP2CB,PHB1,PSMB4,SRSF10,PPIA,PRKCQ,DHX15,CSF2,INA,BUD31,SPTAN1,RPL7,CCAR2,RPL29,NUP153,OTUD6B,FEN1,DOHH,RPN1,IL7,NME1,CCDC32,TLR7,SRSF7,RPS24,SLC25A5,HSPD1,HNRNPA2B1,SRSF4,MCM6,PSMD12,DHX16,SAMHD1,RBM15B,MCM4,NFYA,RAB11A,CUL2,PKP4,SP1,BAX,HSP90AA1,NLRP3,FAS,SLPI,YWHAZ,PI3,AP2M1,SLC30A7,RPS9,APOBEC3G,CPSF1,RAN,EIF3K,PELO,TNPO3,RPL19,RANBP6,EIF4A2,PRDX2,ACTB,DYNLL1,RPL35,CDKN1A,ETF1,RRAGA,CA12,ABCB1,ATP5PO,PSMB7,PSMA3,UPF3B,PSMC1,UNC45A,IL1B,APOBEC3F,MOV10,NFKB1,PMM2,DNAJC7,PSMD7,PSMB1,HACD3,DFFA,AIFM1,ACTA2,KRR1,POLE3,CAV1,ARF6,CGAS,TOP1,EEF1A1,MAP1LC3B,PSMB9,ILF2,SRP72,IFNA13,SFXN1,NKRF,RNF20,ARF4,EIF3E,RIGI,HUWE1,THRAP3,HSPE1,ATP5F1A,NONO,KPNA6,TUFM,DNAJC8,STK38L,CIAO1,IL2,UBE2I,EIF4A3,TUBA1B,ENO1,IFNA10,VIRMA,LDHA,SLC25A4,PSMC4,ATG16L1,EEF1E1,HNRNPH3,RPLP0,PRKCB,FLCN,PPIH,MTDH,RPA3,IDH3A,NHP2,PDHB,RPL4 |
| 6.215e-20 | -44.22 | large_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-carcinoma-adenocarcinoma | 16170 | 4743 | 16828 | 4835 |
SEC22C,ZFAND2A,METAP2,MME,MAPRE1,NRN1,CTXN1,TMA7,SMG9,MUL1,GNG10,RNF144B,ARG2,DNAJB9,GNAZ,RTN4,GLRX5,GAMT,ISX,SIAE,FKRP,LPAR2,ELMOD2,USP15,OR10A4,CNRIP1,TWIST2,APOBEC3G,GNG12,PABPC1,NTRK2,INO80E,DEPDC1B,RLIM,PTEN,UCN,CRLF3,MGAT5B,UAP1,THAP7,CLDN3,ADAM21,SIT1,FDFT1,NEGR1,MOXD1,CCDC160,RPA3,EPHX1,CKS2,RORB,CXCL13,ABHD5,TXNDC12,RWDD3,CENPW,SDHB,GFPT1,ATG4C,FRRS1,SNRNP48,IL1A,BCL7C,OR4D6,THBD,PPFIA2,CNDP2,FBXW11,CINP,METTL15,BABAM1,NEUROD2,PGRMC1,DHX38,GPR171,PTK7,TMEM147,USP8,LGALS8,COX8A,HTRA2,SNAP29,JAGN1,NDUFAB1,TYW5,RPL27A,CBLN2,NUDT12,SPRED2,CDAN1,OPRM1,UBE2K,PIK3R2,PDE1B,PCNA,DDX23,TMEM126B,NDUFS6,CTSC,NXT2,CHST2,HNRNPA0,RHOBTB1,FZD3,CD247,IKZF5,LRRC3,HR,DNTTIP1,FBXO44,ARPC3,DKC1,CREG2,PCYOX1L,AGPAT5,PLD3,MRPL11,SCLT1,LRRTM3,DAAM1,HSPA13,LSM10,ANKRD34B,PPP2R5E,SLC11A2,SH2D1A,UBB,LMAN1,NPSR1,LARP4B,STX11,OR2Y1,PMP22,SERPINA1,SLC6A6,CCDC134,TCF19,SLC30A7,OCRL,ZNF664,MLC1,MAT2B,DDX46,PDHB,TSPAN18,GANAB,RPS6KA4,BBS5,XCL1,RHEB,FBXL14,OVOL1,DHX15,RPS7,PSMD4,NPPC,TRIM15,RELL2,GPX1,RAB27A,GRAP2,SFXN2,SNX22,FASTKD5,CST11,GNAO1,CYP21A2,NCDN,TMEM117,TMEM170B,MRPL34,NDUFB6,IMP3,IRAK4,UBL3,KCNJ3,B3GALT1,COMMD6,AFAP1L2,TMEM30A,GNPDA1,CSGALNACT2,HENMT1,CSTF3,RPL7L1,REEP3,ST6GAL1,TMEM179B,TOMM22,BFAR,TOR3A,GLRX,UBA3,CBLL1,SAV1,TAGLN3,STAT2,EPCAM,PCDH17,SRSF7,PRR3,IL22,ASNSD1,CNTN2,HERC4,DKK1,NR2F6,PSMB1,ZMYM3,CRIP1,ORC5,ILF2,OXSR1,ZNF365,BAG3,TOM1L1,KDELR1,RPS16,KRAS,RRM1,RBM22,BMPR2,COMMD3,PPP1R1B,RND2,OLFM3,SCG3,CCS,RASD1,SHISAL2B,SCGB1D1,NLRP3,ILDR1,CHPF2,NDUFAF3,IER2,HINT2,TMEM101,OR13C8,NUF2,SLC16A1,RPS27A,PCDHB13,TPD52,ELOVL7,DBT,RAPGEF5,DAPK3,DSTN,METTL21A,CHAC2,G3BP1,POP5,PSORS1C2,FGFBP1,MFSD5,MRPL18,PGGT1B,SLC38A7,KCNC1,OXTR,MRGPRX3,MTA2,CCDC86,SUFU,LAPTM4A,FBXL19,CHCHD4,CHIC2,KLHL22,UBP1,MAVS,CX3CR1,SLCO2B1,IGF1R,CHMP4C,CEP19,SOX14,PDAP1,SCNM1,MCM4,FAM177A1,DCTD,THOC2,STARD4,DROSHA,NR2E1,FLOT1,ORC6,FCGR2B,IFIH1,NUDT7,BIRC2,MTM1,HOXC4,UPK1A,RFXAP,EPS8,CER1,POLR1B,CHCHD6,SIAH2,CDCA7L,SS18,MRPL22,CD1C,UMPS,RAB19,ERAS,GSTM5,ZNF326,PLEKHO1,MYBL2,OTOS,CNOT2,CRHBP,CCNY,CHKB,PKP4,GPR176,CLDN12,ELF5,VGLL4,DNAJC19,SCML2,FCGR1A,ADD1,SEPHS2,CLEC2B,CBR3,JKAMP,ODAM,KLF1,VDAC1,FEN1,CLPB,ASB7,PRKACB,APOBEC3H,LANCL2,GLRX2,SNRPB,TPM3,EFNA3,SOSTDC1,MORC2,SSR2,ELOVL1,GPX7,CHRNB2,OR10P1,RIT1,PTPN4,TMEM237,LAMP2,FAM43A,NLRP9,RNASE1,TMEM45A,CGB8,PPM1K,OR8B12,CCL2,LLPH,GSTP1,IFI6,AR,MRPL20,ADAMTS10,EP300,AKAP8L,CEP41,PEA15,RNF8,HSD17B6,APOBEC3F,PLCB2,MAP2K1,PRDM4,FEZ1,OTX2,MAGEH1,EIF4A2,LRRC3B,FPGT,COPS5,STAT5A,IL2RA,PPAN,RCL1,SF3B5,PPP2CB,FKBP8,GABPA,KLHL24,SMAD1,SPC24,AQP2,ZNRF1,CHST13,TIMP3,PRSS12,PPP3R2,PMM2,PRMT6,MPDU1,VAMP8,TMEM70,TTL,ASZ1,CYP2C8,METTL22,USP3,CAPN1,CEBPG,TGFBR2,TNFRSF1B,CDNF,STOM,CTTN,VAMP7,HP,SPIN3,CLLU1,RPL23,SLC2A3,RABGGTB,FBXO7,SEMA4C,ABCG2,MRPS9,LTA,FAM83C,UGT1A1,TOR1B,KANSL3,SPSB3,CCNH,SEMG2,KIAA0513,MNS1,POLB,POLA2,UBASH3B,UBL5,BTN2A2,CSH1,IFNB1,VGLL2,SLC16A10,DIO1,TRMT112,SYNCRIP,SLC35F2,CLDN9,MSTN,PPP1R1A,RPL27,PRICKLE2,RNF148,MTF1,PTH2,CYP1A1,ST8SIA5,PLS3,SLC22A17,TNKS,SPON1,STK4,BST2,PPP2R2C,DDX50,VRTN,HINT3,SLC25A10,CTXN2,RPRD1A,GTF2H5,ZNF821,TEX264,SNRK,ST7,AVPR1B,SRSF2,GSTA1,UBLCP1,SERPINB1,TRAK2,STUB1,PIP4K2C,KLF9,TMEM41A,IL1R2,ACVR1C,NKIRAS2,FAM181B,ATP6V1A,ACP5,HLF,SERPINC1,EGFL7,TMEM59L,FBXO22,REG1B,GPM6B,SLC7A8,RFC3,DHRS13,PARL,UBE2W,POLR2B,TSNAX,GTDC1,LRRC61,UBIAD1,TRIM68,ETF1,LRRC8B,PREB,TUSC1,NFKBIA,NPW,ATG7,TAF10,FAM53B,PRDX1,ACBD6,RNF34,DENND2D,COPS7B,KLF4,OR4D2,OR10A6,DRGX,HDHD3,SHOC2,RPL32,PSMA1,DDRGK1,HMGCS1,SLC25A12,AK3,CLCN6,USP16,TCEAL1,PFDN2,LTB,HARBI1,TMED5,TMOD2,GNPDA2,NAPA,NOTCH2,SOBP,PTPN11,TM4SF19,CRAT,VEGFA,FAF1,DECR2,AVL9,IQCK,TP53INP1,SMPD2,TBC1D13,ASTN1,NCBP2,SOD1,ATXN10,DTWD1,REN,CCR1,TOP2B,OR5V1,GPR173,PSMG3,TUSC2,TIRAP,MYL6,RPS9,GEMIN8,SEC23A,CNKSR3,TCF21,SLC6A3,CASC3,SP2,HEBP2,CALML5,PNMA1,VAPB,CD40LG,FEM1A,TAS2R39,LILRB4,MYC,TMEM50A,SMG8,EEF1E1,VPS26A,CMTM6,CCL28,MKLN1,PPP1R8,ASF1A,RAB35,MAB21L1,KCTD10,SHISA2,SLC38A1,BACE1,DUSP10,TNFAIP8L3,SLC48A1,CDC42,CLN8,ACO2,VPS16,SYK,SLC25A26,PSEN2,SLC35F1,CCM2,ALB,FTH1,SNX1,IL2RG,PIWIL3,KBTBD3,PSMA6,PCSK9,PARM1,CLEC1A,AKAP1,DNAJC24,CD63,AGA,CPSF4,LCN8,NLGN1,TMEM174,MORF4L1,CACNB3,AGR2,TTC23,PCBD1,MATR3,REEP6,CHPF,CNOT6,LAMP3,FAM169A,TNFAIP1,TMEM11,S1PR4,SEMA5A,MCMBP,APBB3,KCNAB1,PPP1R3C,CRADD,AGTRAP,CD28,ZBTB25,FXYD6,NAB2,OR4S2,TLR10,WDR82,APOC4,TAF7,SYNGR2,CYTH2,RNF11,ROMO1,PPY,CRYAB,ATP1B3,GNB1L,DNAJC2,GNL1,SELL,KIAA1143,ZNF473,METAP1,HTR1A,TMX2,ELF1,WSCD1,SFRP1,CCL27,ZC3H11A,PRR5L,CD14,SLC25A39,G6PC3,RANBP6,FGF23,SLCO1B3,GOSR2,CYP2R1,EXD2,KBTBD6,FARSA,UBE2H,ZNF704,SLC2A8,PSENEN,ENO2,OXCT1,PNMA5,MANBAL,CD86,CFL1,KLHL3,IRGQ,BRIX1,DPM2,RNASE6,TP53I3,DDX1,DAP,KDELR2,RPS26,RNF40,CUL3,COX16,CPLX1,ARMCX3,PLSCR3,OR5A2,RBBP4,UBTD1,MAD2L2,TMPO,POLR3GL,COX6A2,ATF1,FAS,ABCB9,SKA1,CSNK1E,GRB10,PIGY,PAK6,ELOVL4,CHMP2B,RBP5,DNAJC4,EIF3D,CCDC92,ERVFRD-1,POLD4,MAN1A2,AKT3,MPHOSPH6,COX4I1,FABP4,LRRC4B,GREM1,TOMM40,ARPP19,GDPD3,ANAPC4,RPL29,GLRA2,HDAC3,MRPL53,PI16,BPIFB4,MAP1S,BHLHE40,KLHL9,TIMM8A,NPC1L1,CARHSP1,POLR2G,COQ10B,AIFM1,SNX14,FITM1,LAT2,ACTR1A,C2CD2L,DNAJB4,TXNRD2,RAD21,RAP1B,AKAP17A,RPL10A,CTDSP2,ACVR1B,CAMSAP2,FAH,SDC2,IZUMO4,ALDH1A3,AHCYL1,ADM2,HMOX2,HNRNPH2,COX11,NPTX1,CLIC4,PRKCA,PAAF1,TFPI,GAS2,EEF1A1,TRAPPC4,UCHL3,BET1L,KLHL26,MMD,WRAP53,MAP3K21,RPL39,TTC33,C2CD4C,OR2AT4,DVL2,TESK1,FAR2,SURF6,BRD3,TMEM108,ST3GAL4,MRPS18B,EHD3,NT5C2,DOLK,ZMAT2,SRXN1,FKBP1A,DNAJC30,P2RY12,KCNS1,SPRYD4,CRYM,SAMHD1,PHACTR1,TPH2,LRRTM2,API5,DGCR8,RNF5,TST,RPL9,C2CD2,EFHD1,LAP3,ADIPOR2,SLC20A1,ALPL,EXTL2,RCCD1,PDE8A,PSMB9,HOMER1,FOXP1,SLC4A10,PYGB,TRIM6,ENC1,SAMM50,KCNJ8,TMBIM6,CCT8,LSM2,PABPC1L,GABRB3,FAM187B,MRPL49,YWHAH,ICAM1,PLCL1,MTMR2,DUSP22,SOD3,ADAMTS20,GFOD2,RPL12,UQCRQ,KCTD12,DNAJC7,CD83,C1QTNF1,ZNF652,ZNF177,PPME1,HSD17B11,TFRC,TTC8,IDE,ZNF267,AUH,IPCEF1,MND1,TSPAN11,GGPS1,UTP6,FOXI3,HMGA1,SH2D5,OR1S1,NTNG2,LRRC8D,ETFB,VIP,DGCR6L,HMX1,WNT10B,RBBP9,SPSB1,FBXO11,BCL2A1,TMEM45B,SPINT2,RGMB,ZNF688,APTX,AP2A1,HRH2,RBM15B,EEF1B2,ZNF189,MIF,ACTR3B,C1D,TFDP2,ZNF22,SH3BGRL,EXOSC3,ATXN1L,SRSF4,NECAP2,PID1,ZHX3,ATP6V1E2,IL7,ENHO,MYL12B,GINS3,ARPC2,GPR146,KCTD11,OPTN,APPBP2,CLEC7A,NEURL2,PDP2,SMNDC1,KRT222,CNTFR,SNX12,POLR2D,SRPRB,ERLEC1,CEP85,DRG1,FGF3,USP13,MED23,SDCBP,NDP,SNX33,TMEM42,CA8,YIF1A,OR10Q1,KBTBD13,FAM91A1,LCN12,KPNA2,CTNND1,RAB3A,DDIT4,SMYD3,MAP4,LUC7L3,HHIP,NMBR,LGALS3,RAD23B,UFM1,USP30,ORMDL3,FOXJ3,HBEGF,AIF1,CALU,CHN2,TMEM60,RPS3,OR1F1,HAX1,EGR2,LRRC20,CSTA,RGS6,RASL11A,CLSTN3,TBC1D19,ZNHIT1,MECP2,NUP35,PRDX4,SLC25A14,ELOVL6,ALOX5AP,TFPT,RPL24,ORAI2,CHST7,SERPIND1,CRYL1,GNPTG,OLFM2,ENO1,THNSL1,SLC1A2,COX5A,CAMP,RHBDL3,TRMT61A,PHF21A,LBR,FBXL7,CYP11B2,GPD2,OMG,CELA3B,RNF181,STYK1,POP7,TSPO,SNRPN,LYPLA2,RPRD1B,DCAF4L2,CHORDC1,ZBTB16,ANAPC16,FBXO34,HCST,DHRS1,PAPOLA,OR5B3,BRMS1L,RHAG,IL12A,SAR1B,CCR5,TLR1,OGDHL,CAPG,RNF128,ACADS,PTGES,VASH1,GAPT,TLR7,PPP2R5A,F11R,ADK,G6PD,RALA,WDR55,FTHL17,EBLN2,SERPINB6,SYBU,EXOC5,NAA15,KIN,PRDX6,AP2M1,TAX1BP1,CRELD1,NFKBIL1,INMT,TP53,PPM1M,PPM1B,TRIM35,TRAFD1,PKIA,HBA1,MZT2B,NECAP1,GPC4,LIMS2,OSGIN2,MGST2,STX7,SENP8,GADD45B,FTSJ3,TSEN34,GSTM3,SYNDIG1,BET1,CYB561,FCER1G,TOX,PTRHD1,RWDD4,KPNA6,IRF8,HEXIM2,TBC1D17,TMED4,HSD17B1,SLC25A46,MAF1,TXN,RPS12,CYB5D2,ZBED3,DAG1,PPIF,SETD7,MTHFS,DUSP6,MT3,EIF1B,OR10A7,ZNF250,SERTAD3,DNASE1L1,PSMA4,PML,GABARAPL2,TNFSF12,TAX1BP3,ZNF790,RDH12,ARF4,GABPB1,CHST9,CPT2,ANP32B,DCAF8L2,AP1G2,NDNF,CACYBP,CTSK,URM1,CETN3,PWP2,MTAP,RAB3C,STX8,BATF,TOLLIP,DUSP1,TGFB1I1,NFYA,FAM200A,S100A10,KLF10,AP3S2,MPHOSPH10,MRPL47,TMEM33,S100PBP,RHCG,ARHGAP21,SCG2,BMPR1A,FAF2,SETD4,OTUD6B,LCN6,COX7A1,FBXO9,CCND1,OR2W1,RPGRIP1L,ACOT13,TMED3,WFDC13,ID1,PTDSS1,SLC35A2,ENTPD4,ARMC8,NPTN,FCAR,CCDC42,CYC1,POU1F1,CRYBA2,DEGS1,ING5,INPPL1,BACH1,MIA2,KIF2A,RBCK1,MRPS25,NOP58,SPATS2L,AKR1A1,NFE2L1,FABP5,MRGPRX4,PGAP2,COA4,CTSD,CYP4F8,PRKD3,SLC5A6,DEK,NLGN2,SCAMP2,OR52M1,NUP107,SPEF1,CD164,PPIB,CDKN3,BPGM,FYTTD1,IQSEC1,NOL4,SIRT7,RRAGA,ETV6,TAPBPL,TNFAIP3,ZBTB42,RAP2B,ABHD16B,MTMR12,DUOXA2,TRAF7,MMACHC,OR2A2,EIF4EBP2,TCP11L1,SOST,ZNF805,HPCA,SV2B,SNAPC1,SNTA1,NDUFAF2,GPR37L1,EMC4,GFOD1,SIVA1,SPRED1,POLL,NONO,ALDH1L1,TSSC4,SLPI,CERK,USP39,USP38,ZNF174,FGF13,PRKX,PROX1,SYNGR1,LSM6,ZMAT5,RTP4,ENPEP,NAB1,VPS4A,CLEC12B,SFTPD,CYP2D6,INTS12,SOCS2,RAB8B,CTNNB1,CDK6,CWF19L1,ESR2,DCAF5,ADCY3,FAM13B,SNRPD2,MSX2,KRR1,NLE1,PELI3,SNAI3,CDC37L1,CXCL1,XPOT,PDIA3,FRA10AC1,EIF1AD,APH1A,NDUFB8,ISYNA1,STX17,LEPR,WNT7A,DHX16,TRA2B,SOX21,RAB4A,HADHA,LEAP2,HSPB1,KCNA2,B4GALT6,LHFPL1,OR6M1,NUDT16,GXYLT1,SIPA1L1,STAMBPL1,PGBD2,HSPE1,ZKSCAN1,CLDN14,RPL37A,SERPINH1,OXNAD1,HEXA,ADAT1,OCEL1,BRI3,RBM23,TMED1,CD3G,BRMS1,PAOX,CDKL2,GAS8,CHRNA7,KIF1C,OPA3,TAC1,AKR1C2,IGFBP4,LMBR1L,NPVF,IPP,NQO1,SPATA2L,TBCE,IL34,DFFA,ST13,LPXN,RASGRP2,FBXO30,TIGD7,POLR2I,CD2,ACAA2,UCKL1,RAP1A,WWP2,RABAC1,CXCR1,NEDD8,FGF17,HBB,PTCRA,CCL21,NDUFA5,KCND2,THOC1,ABCC5,RANGRF,NUDT19,RC3H2,DNAL4,ATP2C1,FATE1,PCDHA5,SLC20A2,NUBP2,LDHA,PFDN6,UBXN10,PRCC,GSK3A,APOBEC3C,GPR162,RNF187,SLC7A4,ZNF513,ZMYND11,EXOC2,XPO1,THRAP3,EEF2,KIAA0040,EFHC1,SLC25A32,GJA10,TF,CREB3,RNF103,XPO5,INTS10,SURF4,SPOCK1,LASP1,PHKG1,MOB3C,UTS2R,NEK7,WBP2,GTF2A1,FUT8,GALE,EIF2B5,SH3GLB2,ENDOD1,ANKIB1,CIRBP,CXXC5,OSR2,EIF4EBP3,WDR37,ZSCAN1,OR51S1,SLC39A9,DHX9,FURIN,IL23A,PSMD6,CCL25,GNMT,AQP4,TXNIP,CREBL2,GLE1,PYGM,OR4K1,SHC1,HCRT,CAMK2N1,FGFR1,CD200R1,CRYGB,KCNJ11,PPP3CA,RCVRN,FAM89B,PEX3,CCDC127,SRP54,BUD31,TMX4,CAMK2G,PRMT2,TACR3,CIB3,GHITM,TUBG1,RPL15,CACNB4,CCDC47,SCFD1,TTC4,PRPF4,ZNF593,ARMCX5,FKBP14,IDH2,RAB18,IMPACT,AGER,CD58,SBK2,SORD,SLC39A7,CCT5,ENPP4,PSMB5,MCOLN1,SMCP,FBXO32,ANAPC2,AGK,ARMCX2,SIX5,TRIM21,ACTA2,GALNT12,ARFIP1,PPARG,SPR,PTPN1,HNRNPC,SETD5,NFIL3,TRIM37,HECW1,ZBTB38,SLC25A21,RBBP7,PGS1,RMND5B,TRAPPC1,FAM199X,CLDN11,PAEP,NIPA2,RABL2B,LRP12,NPY2R,SPTAN1,SLC35E3,RNASET2,RFX4,FRMD8,ADRB1,PKNOX1,ZDHHC14,RBM17,PCDHB8,HEY2,ZNF24,FBXO42,TMEM215,SERPINB10,TSEN54,ATP6V1G1,MEST,FZD4,WDR77,MTPN,ZCCHC10,SYN3,GPBP1L1,MX2,AAMP,LYG2,MFSD6L,DEFB116,TNFAIP8L2,DHRS3,DNAL1,NDST1,KTI12,RAB3B,CDCA3,SMAP2,PSME2,AZIN1,FGF1,HBE1,ABCB1,AZGP1,INO80C,LBH,JAK1,CCL19,TBC1D10C,NKX3-2,MAGOH,MLF1,GTF2E2,P4HA2,JOSD1,SUPT7L,LSM3,AFTPH,OR4D9,KIT,RS1,CSNK2A1,PIWIL4,KPNA1,RARRES2,GRSF1,GSTO2,KBTBD2,CTNNBIP1,GNG7,ATF4,PGK1,ROPN1B,VRK1,MYH2,SNAP91,PACSIN3,HEBP1,ALKBH4,SLC7A9,TMIGD1,DNAJC5,CDC73,ZYX,UBAP1,LHX2,DYNC1I2,S100A6,CYP27A1,BTF3,MMP9,OR4D11,GAL3ST1,CASK,LTBR,PRPSAP1,TCP11L2,GRPEL1,ELMO1,FGFR1OP2,GABARAP,UBE2D3,ATP6V0E1,CCT2,CHRM4,UBE2A,ARMCX1,TRIM23,NAIF1,NHP2,P2RY1,STRBP,ING1,OR8B8,IRF1,CCR6,ZMYND19,SLAMF9,TAAR1,XAGE5,SEC14L1,ZNF319,ID4,ZNF397,APOBEC3A,NCKAP1,NRP1,CDK5R1,GLUL,CNIH4,LMO4,CLU,ATPAF2,KIAA0232,FAM8A1,NCR3,EIF4H,ITK,MYL12A,CYP39A1,HSD11B1,SWAP70,LRRC69,GNRH2,CHDH,IDH3B,GALNT4,CTNNBL1,GRM2,CYP11B1,SENP5,ADGB,JAKMIP1,GPAA1,TLR3,SLC38A9,OSM,IL15RA,FAM78A,PPP1R2,MIOS,RMND1,MEF2A,IMMP2L,SLC35A1,HSBP1,DHRS4,ENY2,RAG1,SNAPIN,KLK3,SLC30A5,MRPL50,MRPL24,ZNF304,TOM1L2,UST,EXOC8,PFDN5,LYAR,NUDT3,B9D1,RND3,CNP,AK2,SOCS5,GALNT1,CCDC69,PSMA3,SPRN,TMEM156,GSTO1,MRPL13,MDM2,MGP,EHBP1,TLR9,FIBIN,WDR38,SNX20,L1CAM,FGD2,APEH,AKT1,DLX1,COMTD1,FNDC8,DKK3,IL20RB,SF3B4,PRRC2A,DPP10,RPS23,CRABP2,CDO1,ASMT,CCNI,PPIL4,RAB11A,SLC17A5,SLC25A31,ZNF671,LYPLA1,LIG3,RPS14,UGCG,MEAF6,ZNF207,TMEM219,ATP6V0B,EDF1,TMUB1,C1QC,TRIM3,POLR3H,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,E2F6,GFM2,MRPL23,GDI2,ARHGAP1,DOK4,KLK9,PLA2G5,KLHDC8B,RNF141,TRIM32,SDR42E1,PDIA6,UBR7,PRIM2,SNRNP27,CD99L2,TRIM54,RPLP2,FAM98A,ACBD7,CDC42SE2,POPDC2,GPX6,TGIF2,GREM2,CREBBP,PRPF19,GPAM,PDCD4,LDOC1,RDH10,OR4Q3,HTR1F,NKIRAS1,OAS1,GIT2,SDF2L1,RUVBL1,GTF2B,CXCL3,RAB3D,CLDN4,SLC13A5,LAMB2,TMEM184B,KDM4B,ZNF287,TMEM114,ACAT1,EDEM1,GNG2,VAMP5,METTL14,PTS,TOR2A,AMIGO1,JPH4,GTF2H2,MBL2,MAP3K11,SMU1,SLC35D1,COL1A2,RMI2,SAT1,R3HCC1,CSGALNACT1,METTL2A,ABHD6,CLDN1,TFCP2,AKAP14,NDUFAF4,CRYBB2,CCNB1,CTDSP1,FAM162A,ANKRA2,ADIPOQ,ALKBH5,ERH,CRTAP,LCP2,UHMK1,IK,ISG20L2,GPHN,POLE4,HSP90AB1,FUNDC2,MRPS23,ZNF862,ATG4A,SYP,CSRNP1,CDKN2AIP,RGS7BP,SFRP4,RER1,FCN2,AIF1L,CCR2,ZC3H7A,ZBTB5,DSTYK,TMEM123,ARMC7,ATAT1,CIDEB,TMSB10,IPO8,OPRK1,GCNT3,PGPEP1,F9,NKX3-1,CYP2C18,NDUFS8,ZNF740,MYO6,BCS1L,SNX17,APOO,GPR137,NRSN2,TMEM144,TOP1,SRRM5,EIF2B3,DNAJC22,HTR5A,TMX3,PAPSS2,TCF23,CHGA,GBE1,SEC61B,TEX30,GPR65,TOM1,BCL7B,OSTM1,CHMP2A,EMP3,HSPA8,MSMP,SLC19A2,CBR4,VMP1,ADO,CALHM2,GMPPB,LMNB1,BECN1,TES,CCDC25,FAM219B,ABHD14B,MRPS16,EED,ZNF592,MTRF1,YAF2,ELP3,CIB2,TGFB3,TRIM24,DTYMK,MRFAP1L1,ACSL4,B9D2,EWSR1,TMEM204,PROS1,GPX3,SSU72,IGBP1,AKAP12,RAB40AL,DDX39A,SNAPC3,SNCG,BLOC1S2,CALHM3,LHFPL4,CDKN2C,COX4I2,TMSB4X,TRIM5,EIF4E,RINT1,TSPAN5,OR10G9,BZW2,SPECC1L,NAT2,KHDC1,CD274,EIF3K,B3GALNT1,CREB3L4,BCAP29,ZBTB17,FABP7,NTN4,RTKN,ADIG,HOXD12,PHYH,FUT9,UBE2V2,IL10,RPLP0,OLFML3,TSPO2,GOLGA7B,EFNB1,RNF113A,PREPL,SH3GLB1,THTPA,TFE3,MT1M,DEFB114,IFNA10,PELP1,CSNK1A1,ITGA6,COMMD8,STOX2,PCMTD2,KLC2,PAX9,STXBP1,MTHFD2L,CD36,IRF3,UQCRH,DPEP1,PRKAB1,DERL1,IL18,ST3GAL1,SOX2,CSNK1A1L,PARP11,SLC32A1,ST3GAL5,POR,CEP97,ZNF501,IFRD2,RAC2,NDUFB4,STK24,LCA5,PYROXD2,MRPS21,LRP6,TAS2R40,NR1I2,CNNM4,CDK4,NPR2,KCNK13,TRAF2,RBM7,BRCA1,PCDHB1,ABHD4,MBD5,KCNMA1,BCL10,NOS1AP,PDHA1,ADPRH,NME1,DUSP19,RGS2,STMN2,SLC41A3,SERINC3,TMED7,DNAJC3,RNASEH1,FKTN,KLK6,STAU1,STOML3,TSN,FOXN2,RBFOX2,GK2,CDKN1A,SLITRK2,ELSPBP1,ORAI3,STX18,SDHAF2,CLIC2,MED11,PPFIA3,OTUD7B,PIWIL2,SOS2,AKIP1,GYS1,SLC23A2,ROGDI,PGM2L1,UBE2D1,LY6G5C,SLC4A8,SNIP1,FAM168A,ACTL6B,INHA,RPAP2,RGS5,OR5L1,RAB1B,HRH3,ABHD13,ZBTB45,AMY2B,NDE1,RBMX2,HMBS,TDRD7,CD2BP2,CCDC65,LDHAL6B,SELENOV,GRIA2,LRRC24,FLYWCH2,MRGPRX2,DDX4,KLK5,LIX1,CAB39,ZCCHC9,SLC43A2,CASP12,TMEM91,B3GNT2,HIGD2A,TEX12,TOP3B,PNPLA8,MYEF2,TAF5L,MOV10,NGB,UQCR11,GLT8D1,TMEM14A,GDE1,TCEAL7,PCGF3,GPX5,TRIQK,OR14J1,CDH8,CPSF2,BEND5,SNRPA,CMPK1,TRAPPC6B,VAMP2,CCNF,RAB2A,CTNNA1,GPIHBP1,WDR44,CD226,SACM1L,VPS33A,CRBN,PDYN,ZFP1,B4GALT3,EZH2,ARCN1,INPP4A,KCNIP3,AMT,RAB9B,PHYHIP,WIF1,FN3KRP,DYRK1B,OR10G7,ISG15,SNX24,ACADSB,STAT6,EIF4B,PPP2R1A,PTHLH,MRTO4,SLC25A4,SMAD3,TIMP1,TXNL1,DERL2,ELMOD1,MLF2,PLEKHJ1,RPL23A,LYNX1,TMEM59,IL6ST,FOLR1,RAB37,SLC6A11,CSTF2T,FBXO25,PSRC1,IFI35,C1QL1,CAV2,TIMM10,STK38,RAB5C,PNP,PCDH19,WEE2,AP1AR,SMN1,CCR3,OGG1,ZNF687,OPHN1,SUMO3,PTGER1,SFT2D2,RAB23,CMAS,WWP1,RHOJ,CBLN4,HIRA,S100A8,CD47,TMEM50B,IFNG,JUN,TNRC6C,SPTBN1,CHI3L1,RNASEL,FERMT2,TOMM40L,EIF3J,GNPNAT1,GIMAP2,UTP23,DNAJC8,PPDPF,TNFSF18,FAM107A,RNF167,RAB33A,CRYGD,EGLN3,FOS,DYRK2,POMP,RPL26,OS9,MRPS28,RIOK2,OAT,HNRNPK,PAFAH1B3,PRKAG1,NFKB1,ACAP2,MAFG,SCD5,LHFPL2,GGCT,RCBTB1,ATP6V1C1,TAPBP,HNRNPA2B1,OR2A25,STX6,FANCG,PLA2G15,NAA60,CCL8,RFTN2,TPPP,RB1CC1,CAPZA2,SLC35E1,ABRACL,YPEL5,PPID,POLR3B,HAND2,PGR,LCN9,BRD9,CXCR4,HSPA14,CDH13,NPY5R,KIAA1191,CCL17,OR2H2,PAFAH1B2,DLG4,GTF2F2,KCNH1,RNF122,NAPG,KIAA0408,BICD2,SERPINA5,CREB1,TMEM177,FMO2,RPP25,RBM12,RAN,SQSTM1,GLIPR1,TUSC3,SPRR1B,RPL6,CLDN8,ADAMTS1,CXCL14,BNIP3L,SLC7A14,DDX42,PPP1R16A,MT2A,ATP1A2,PXMP2,CYB561D2,GMPPA,GCA,ISCA2,UPF3B,RABL3,ZNF576,FCHO2,CHST1,MPV17,EHD1,PPP1CB,TRAM2,TRAM1L1,SESN2,PLAGL1,PAPOLB,RFXANK,KLHL15,ACTR2,OR4F6,CRYBB3,PTRH2,FOXS1,TMEM203,TAS2R5,APLN,ACP6,SYNJ2BP,TMEM164,KCNK10,SLCO1A2,TMCC2,ZNF609,PLEKHA8,KRT7,GJB2,WDR3,MANSC1,SRP14,NUS1,TMEM106C,DLK2,CDK12,DMTF1,PLG,FBXW7,TNFAIP6,PSMB7,KCNJ2,GXYLT2,EPHA4,CPLX3,TNNI3K,GCLC,PSMD10,NPY1R,CITED1,ARL4D,LIAS,PRSS23,PLCB1,GPC1,GPR17,ZNHIT6,ING2,ARL2BP,TSR2,CHRM3,FAM149B1,FRZB,SPP1,SURF2,SLC29A1,MAGED2,GJA1,TM4SF20,CCNA2,AASDHPPT,REEP4,RNF222,ABHD8,ICAM2,STARD3NL,YWHAZ,CAPN2,LSM14A,SLC8A1,OR8H3,BOK,TM4SF18,OR6X1,TNR,FAM81A,CEND1,ZNF511,EHD4,HNRNPF,STAMBP,SLC25A1,CXCR3,MAGEB10,HOMER3,ADORA1,SLCO3A1,SPATA2,SHPRH,KCNJ10,TAF1D,PCGF6,GRM1,OR4K2,B4GALT4,CAV1,RPS2,LXN,TCEAL8,YIPF3,TRIM34,TMEM205,NDUFC2,ITGB5,RGL2,BLCAP,NINJ1,ICOS,MRPS11,RAB39B,CSNK1G3,AKR1C1,CNTROB,FTSJ1,SREK1IP1,PRND,CPLX2,ABHD10,HUWE1,MEPCE,EIF3G,PMAIP1,TTPAL,UBE2L3,CCIN,PDE4B,CYP3A43,SPEM1,CREBZF,PAQR3,PROK1,JAK2,TRIM36,NT5DC1,MRPS18C,LY6H,LILRA2,TNKS2,CBLN1,STK3,COMMD9,HSPB2,PTP4A3,PLSCR1,DCAF12L2,CTXN3,ZBED1,PNMA3,DPH5,CORO6,OIP5,TRIM29,RB1,HCAR1,TMEM127,GSTA2,FAM53C,MCL1,ALG11,HFE,DDAH1,GPR35,NDUFA1,CGGBP1,RPL26L1,PHF13,BANF1,ABHD12,NF2,PARP2,FOXA3,KLHL1,SESTD1,CARTPT,IL17F,PPAT,CYGB,NUDT9,GGH,TNF,KLF3,CHRAC1,CCR4,TFB1M,SUMO2,SNRPB2,LZTFL1,CD81,LRRC40,CRISP1,DPH3,ELK3,MT1E,FSTL1,POLR2L,POLDIP3,RHOBTB3,HGS,TRAPPC13,UBE2E2,TAS2R13,DBR1,TSPAN17,PRKRA,WDSUB1,GNRH1,PRKCE,ZNF451,TMEM170A,RNF133,COX6B2,CDC20,WDR5B,ZDHHC4,ADTRP,SNRPG,TIMP4,XRCC5,ACCS,FHOD3,SLC35B3,NHEJ1,WDR11,TYROBP,TBC1D25,PEX13,AIPL1,NBN,VMAC,TNFAIP8L1,SEC13,IL2,CDC7,PRL,MPPED2,NDST3,FBXO8,SLC19A3,OLR1,SGMS1,MGAT4A,RBBP8,DUSP21,TRIM45,ATAD1,MRPS34,CYP2C9,IGSF11,TPPP3,ZNF263,USP6NL,MTDH,SGTA,CA2,SNX10,GTF2F1,DLST,TMED9,E4F1,GSTCD,BCL6,SYNPR,SSX2IP,BCL9,ASPA,TRPC1,ELMO2,LYPD6,GTPBP8,HS2ST1,DR1,CBX3,MIS12,TMEM89,GABRA1,CAND1,PRNP,HSD17B10,VTA1,RPIA,PIK3AP1,XAF1,PICALM,COX6C,LST1,COCH,FEM1C,ATP1A3,PEBP4,BAX,GH1,PSD2,NUDT2,TMEM38B,TSPAN15,NPM3,CRTC2,GSTM4,JAKMIP2,PSMC3,CDH11,IVNS1ABP,PIK3CA,FAM83B,PAIP2,NDUFS2,TMEM185A,AKR1B1,TAB1,SF3B1,APEX2,ADORA3,AP1S2,LY96,MAD2L1BP,TMEM47,ANKMY2,ZBTB39,RBM27,CPT1B,CNN3,MREG,ACER3,DIRAS2,SRFBP1,EIF5B,ARHGAP12,PFKFB2,PDE12,ANKRD6,FAM161A,YTHDF2,OR13A1,MAGEC2,PSEN1,LMO2,FKBP1B,EDA2R,LCORL,AQP11,RBP2,CLEC6A,KCTD17,RASSF8,SSBP4,PDE7A,DUSP3,SUCLG2,ZNF581,VPS18,GHRL,KIF3C,ATP8A1,CIAO1,GJC1,SLC12A2,RUNX1,RPS20,NAA16,ZFAND6,TYMS,MED10,TAPT1,SCML1,CLDND1,ETNK2,CCDC106,SPRY1,RPS10,KRIT1,VPS72,FUBP3,KCND3,ROCK2,TRAF6,TBCCD1,RPL18,TKTL1,GIN1,MGMT,ITM2B,MTCH2,SP1,CCSER2,TRAPPC6A,MDC1,IMPA2,UBA52,FUNDC1,AP1M1,ECHDC1,TRAM1,TADA3,SULT1B1,RPE,OR8B4,TMEM165,KLHL25,IRF7,VEZT,SLU7,MFAP3L,PTP4A2,FAM3C,OAZ1,TOPORS,LYZ,WSB1,PRR13,SLC25A5,SLC35E4,FAM136A,ZNF518B,CYBRD1,ADCK1,MACROD1,FAM151B,MRPL9,UBE2G2,FEM1B,MRPS17,SGIP1,MECR,UPRT,SUPT3H,FXN,RAMP3,TMBIM1,IFT172,CYTH4,CPNE2,TOX4,KLRC2,CENPL,NUCKS1,IER3,TRIM26,GRIK1,CMA1,DLGAP4,SNRPE,RRAGB,GALNT2,ANXA4,RASL12,IL18BP,GMPS,PELO,TTC9C,GORASP2,THUMPD1,SNAP25,RXRG,IGF1,CCR7,CDC23,MBD3,ELFN1,DMPK,MPG,SYNGR3,TANK,BRAP,PIH1D1,KCTD3,RDH11,NKAP,LBX1,ELFN2,RP9,GALC,HAUS2,OR5M9,CNPY1,GNGT2,SSPN,LRRC8A,CAP2,EXOC3,SAP18,TMEM81,DDR1,SLC22A6,TIA1,SPG21,EIF1AX,HSPD1,RNASEH2C,PARD6A,TCEA2,LRRC28,PNPLA4,PIAS1,NUPR1,NPC2,TMEM115,BTG3,TMEM183A,DPEP3,GRPR,GADD45A,IGFBP3,OR1M1,CD9,RUSC2,S100A11,ZNF622,ATG9A,TGFB2,RBMS2,SLC25A27,VPS54,GLOD4,PIGA,BOLL,MX1,TRIM44,PAIP2B,LRP10,NR1I3,BTG2,ITGB8,CCDC3,VAV2,CMC1,NUFIP2,HINFP,GNB3,TMEM229B,NRM,MPV17L2,CRYBA1,WDR45,THAP8,HSPB6,HSPA5,SERTAD2,GNA11,FHL3,FAM20B,TICAM2,GPRASP2,PQBP1,PPWD1,CD209,ST3GAL2,TAS2R7,P2RY4,FBXW4,IL2RB,PTGFR,IP6K1,GK5,SSNA1,GLCE,SPINK9,SLC25A24,PDCL,SUPT5H,STAR,RPL10,TRIP4,PSMD3,DTWD2,GPR160,POLR1D,CYP4V2,APLNR,CNPY3,SRI,NCAPG2,OR51E2,GP9,KRTAP8-1,POLE3,RNF10,TEX261,OR4D5,ZDHHC16,RAP2A,MSH6,MDFI,PPP1R11,CRY1,TNFSF15,SLC6A2,AIP,CD40,TLR8,PMPCA,NOG,MED22,ARFGEF1,PYCR2,TNFSF8,CDIPT,ZNF428,PDE2A,RGN,RAB6A,FKBPL,CTTNBP2,CDK7,SIN3A,SCAND1,PSMD7,PLAC1,OR4A47,DCTPP1,TMEM100,EID2B,PRCP,FBXL4,CD34,THAP1,UNC79,CPXM1,SRPK2,TAB2,TRAF3IP3,PIWIL1,RGP1,CCDC90B,RPA2,TMEM107,LDB2,PRSS8,YPEL4,GADD45G,RNASE9,BAD,TSPAN3,MGST3,OLA1,HAS3,PRPS1,CRHR1,AKR1E2,UQCRC1,NOC4L,LRRN4CL,GDAP1L1,SSBP2,PDCD10,RPL31,WTAP,C9orf72,NAA30,NETO1,PTGER2,CDR2,HSD17B8,IRF9,LSM4,CGRRF1,DDX39B,HERC3,PSMB4,SEMA3C,DOK6,SKAP2,CLK1,RASSF4,KCTD20,SERPINA3,TRAF1,RSL24D1,ZMAT3,BRS3,SLC15A1,KCTD16,PLEKHF1,AHSA1,ZBTB6,HNRNPAB,GPR78,TRIM62,ZNF655,TEX19,CD200,TMEM220,ST8SIA4,USE1,TMEM168,NCK1,SIAH1,LRP3,STRADB,PHOSPHO2,SCG5,TRAPPC2L,TMEM198,RFX5,MAT2A,NMRAL1,OR6C4,CDKN1B,COX7B2,CMBL,HMGN4,SCHIP1,TAF9,MEA1,HOXB8,SSH3,SEC61G,CENPM,EMX2,GFM1,PRM1,GAL3ST4,ADIPOR1,SLC7A11,POPDC3,RETSAT,FZD6,MET,RPLP1,SNX11,TIMMDC1,MT1X,UBE2V1,SERPINB9,PDE6A,HELT,TRNP1,IMP4,RHOU,B3GALT4,DLG3,RPL22,CEBPE,BHLHA9,TMEM176B,RANBP1,ATF3,RBM5,CTLA4,PRSS37,PDLIM3,MAP1LC3B,ACSS2,IFRD1,DEFB1,GMDS,WNT2,LDB1,CSRNP3,NRGN,TRAPPC3,MFSD3,BIRC5,ESYT1,F2,ARL5B,CAMKV,YKT6,VPS26B,ANKH,AANAT,SAP30BP,HAPLN2,EDC3,TBCEL,PRSS35,FKBP2,UNC45A,RALB,NUDT1,ISG20,TMEM87A,CYP26A1,GMNN,CTDSPL2,ANKRD46,ABHD2,ARL6IP5,CEP70,SNRPA1,SNN,DTL,KDM1A,NDFIP1,CCDC22,OSBPL8,CEP57L1,ARHGAP19,TACR1,DIS3L,CA14,EMILIN3,MTA3,DRD3,NAP1L3,CEACAM5,NACC2,CHRM5,GPR34,TBC1D1,TIMM13,XBP1,RPF2,PDLIM4,THG1L,ERCC3,GABBR1,LIPT2,HPCAL1,MRGPRX1,SEMA7A,NAP1L5,MED4,ZCRB1,APOC2,CYB5B,TRMT5,OR9I1,BCKDK,RPSA,PIK3CG,NPBWR1,ERLIN2,UBE2S,HYAL2,RHOH,ARHGAP15,RACGAP1,CORO1C,CCDC126,RRP7A,RBM3,STT3A,MAGEA4,WBP11,ZNF436,EGR1,DIO2,STARD7,ZNF343,CHTOP,SYPL1,GPR75,SETD3,TMEM126A,GNPAT,FOSL2,ACP2,ACTL6A,TMEM231,TCTA,PCP2,SOD2,ADD2,SCN2B,ANKRD10,TEF,PDCD1LG2,GLO1,RAB1A,VSTM4,AMELX,NEU1,CNOT8,PELI1,PIGK,FBXO31,VSTM2L,ZDHHC17,MAP1B,MLN,KLF12,WDR12,AKT2,ITPRIPL2,GAB1,JMJD8,PSMC5,APEX1,PRSS1,SOX9,CHST10,KCNG3,GPM6A,COTL1,PNPO,OR2D3,RFC4,LCN1,TLR5,TICAM1,HS3ST3A1,RIMKLB,AQP3,ETFA,PRELID1,ECD,CD59,HTR2A,SMARCB1,STAP1,ACTR1B,SUGP1,ABCC2,FMO1,STARD5,DEXI,ALG5,DCAF16,SRD5A3,CLRN2,REG1A,PLCXD3,C1QL2,TSPYL4,OR4K13,DNM2,GTF3C4,MMP20,SKP1,CHCHD2,GCHFR,GJB1,PRELP,KRT8,PCYT1B,CSF2,LCP1,AGGF1,HNRNPH3,ZNF200,TPST1,IZUMO2,TP53TG5,DIRAS3,HDAC11,SIGLEC5,ATG16L1,TTLL10,SUV39H1,RGL1,RPL4,SEC14L5,SPAG11B,HBP1,DYNLRB2,CKS1B,COPE,RBM41,SLC25A3,RWDD1,HCFC2,PABPC5,IRF2BPL,PRKCB,DCTN3,LSM5,HS3ST1,TULP3,SPDYE4,OR4M1,BMPR1B,SRM,MED27,RANBP10,ADH1B,MPP1,BARX2,PSMD1,CRYBA4,RAB32,PITPNA,FOXC2,CRYZ,BLVRA,APOBEC3B,FAM193B,PCBP4,MLH3,VWF,GPR37,ESD,CDKN2D,ATP6V1D,ART5,TMEM39A,CDK17,CHMP1B,PSMB10,SART3,IFI16,PTPRZ1,VPS39,FAM174A,SUPT4H1,MYLIP,CFTR,ATG3,INA,OR5AN1,CLP1,CLPX,TNPO2,THOC6,PYCR1,HINT1,RXFP2,RAB9A,RPAP3,CCL11,MARCKSL1,SLA2,SDR16C5,IFNAR1,FMOD,ADRB3,CMTM7,SPATA4,CA12,SLC7A1,TBC1D16,CSRP1,IRF4,LEMD3,RAB11B,STX5,ARL6,CCND3,OPRL1,HSDL2,LYPLAL1,DYNLL1,SMG5,NUP62,RNF139,ABCF1,DUS4L,PLP2,SRP72,DDIT3,SLITRK1,EDEM2,FIS1,HCFC1R1,CACNB2,RPL28,CYP4F22,ARFGAP1,PIGC,MVD,STK38L,CDC26,SHC3,PREP,ALCAM,JUNB,SNRPD1,CCL24,LIPA,PTPN5,RELL1,SMAD9,TIMM17A,RNF182,PGAP3,LCN15,MB21D2,MCCD1,SLC39A10,BCAS4,HM13,TCEA1,VCPIP1,WBP1L,PITHD1,SMARCE1,LEP,SH3BP4,ASPM,EFNA5,ZC3H14,CBFB,TADA1,CETN2,ZC4H2,IFNA13,CACNG3,RIT2,TNIK,S100B,LRFN3,OR4B1,OR5K1,PDE6D,PDZK1IP1,UBE3A,RCHY1,FAM20C,SPHK2,FGR,MRPL12,ARF6,PPT1,B3GALT2,ZDHHC24,DOK5,MAP2K3,SEC22A,DCTN4,RPL7A,CXXC1,LSM12,FIG4,PNRC1,LAMTOR2,SLC41A1,MFAP1,MXD1,UCP2,TMEM106B,UBE2I,FHIT,ARL11,KRTAP4-1,MAP3K3,RNF7,MRPL16,TECR,ARGLU1,EZH1,DICER1,MAGEB1,SLC6A7,ZNF362,POU5F1,HBM,MSN,FGF16,DDIT4L,RNASE4,SAP30,SLITRK5,IL21,RPL19,TDP1,SPCS1,MID1IP1,GLIPR2,SERINC1,SNRNP70,PLEKHF2,ASCC1,CDH7,SLC37A4,SMUG1,DUSP18,UBXN2B,ZNF770,TPD52L1,ZNF345,KIAA1958,EID2,MAEA,FBLN5,FOXD3,LYRM2,CXCL10,BGLAP,COX7B,CDC42SE1,FAM83A,NOL12,RHOG,SDHC,RGS1,ASB11,TTR,SEC61A1,GAD2,RSBN1L,METTL18,THAP6,TUBA1B,CKB,MRPS26,PHF7,HMGB1,GNG11,ARF1,EIF2B2,ZMYM6,BTBD10,EMILIN1,PRDX3,PDCD5,LRRC14,ZBTB26,CTSA,DPAGT1,PPIL3,ZCCHC7,PHTF2,LPCAT3,GPR83,ZHX1,SERTAD1,KCNIP2,FA2H,ERRFI1,HNMT,IFT57,MYH1,ACVR1,DCTN6,VDAC2,ICA1,YWHAG,BCL2L1,LYZL4,PLEKHO2,CST3,DMAP1,LRRC8C,TNFRSF9,KCNB1,ZNF32,NOP16,OR4E2,BAZ1B,PEX26,OR7D4,PPP1CC,PAQR8,ABCE1,GINS4,PRRT1,DIRAS1,SDS,CYP7A1,NUDT4,RPS24,MCM6,DCUN1D1,ADH1A,EAF2,DCK,ITM2A,FITM2,AMACR,NR0B1,MRPL36,DEFB129,SPOP,CYB5R4,TRIM22,SLC52A3,SLC15A2,CASP4,TPRA1,SASH3,TIFA,B2M,ISOC1,ZDHHC8,EDDM3B,MCPH1,NKRF,RETN,LRAT,TCOF1,PSMB11,HSP90B1,VIPR1,QRSL1,FBXL3,RPS15,ASB1,PTGES3,RGS10,GATAD1,ACTN4,SIGMAR1,IFNK,ATP2B4,CFDP1,DUSP9,MRPL17,RBPJ,CXCL9,MRPL33,UQCRC2,RNF152,LRRTM1,EGLN2,TPPP2,EDEM3,KLHL28,UBTD2,IREB2,HNRNPL,EMX1,PKIB,TAF11,NMRK1,CD80,ADRM1,RABIF,CNOT7,KCNH8,TCP1,CRMP1,CH25H,OR2F1,HPS6,SLC35A5,TMEM19,CDC5L,LGI1,CLRN1,TBC1D5,DBH,SNX3,CHCHD1,ARMC6,NDN,SIKE1,MMAA,PPIC,GOSR1,IGF2BP1,RUVBL2,NCOA5,NFE2L2,NGRN,DBNDD1,RAD1,GIPC3,CCDC167,LPAR6,GNAQ,POLR2C,PITPNB,SMAD2,USP46,GPN2,SLC6A1,TLR4,GPT,SRSF12,MYO1B,SLC2A1,QSER1,ADRB2,VAMP1,GLYATL3,PAK1IP1,CBX7,COL3A1,FGF22,CX3CL1,PSMB2,ADRA1A,PEBP1,TNNI1,PTGDS,IL5,CTTNBP2NL,VDR,SMURF1,PI3,EIF5A2,PMP2,DPPA2,PSKH1,FKBP4,STX16,NGDN,CCL1,UBE2N,ANO3,PRR19,NCSTN,ANXA7,SGMS2,TAF2,PFDN1,LIN7C,SSR3,GPR22,SLC38A2,HS3ST5,PLAC9,NKX6-2,P2RY10,IGSF21,CDK2AP2,PRPF18,EPHA2,CAV3,MAPRE2,FGF7,UCK2,LMBRD1,COX6B1,SLC31A1,DIO3,ITGA2,SRSF1,OR2J3,OR10G3,G3BP2,DCLRE1C,SUMO1,ZNF574,EXOSC8,POLD2,KLHDC8A,KDM2A,TSPAN7,FADS2,F7,ACOX1,PIK3R1,IFT52,KCNK17,ZGLP1,COPS4,NCALD,ANGPT1,IL12B,ACOT6,WDR6,KLHL23,HSDL1,CBL,INSIG2,DEFB124,LHB,RAB6B,MMP14,ATP6V1G2,MRPS35,MRPL41,MRAS,RALYL,FAM168B,ELK1,MDH1,CYP1B1,DDI1,COX17,RAB28,GKAP1,RPL17,SERPINB11,UBL4A,FGL2,FABP12,HDAC5,HECTD3,PI15,GRIA1,RNF208,YES1,CLIP3,SLC25A42,VAC14,CBLN3,CRYGA,GAPDH,HSD17B3,PCCB,ESAM,NEO1,ANKRD50,RLN3,CHMP1A,NXT1,SLC35C1,MED13L,NSDHL,TMEM97,RFC5,JRKL,PATE4,IDH3A,PSMC4,MPST,MADCAM1,POU3F4,MFSD6,ASRGL1,TSSK1B,PICK1,NTRK3,CCAR1,GGCX,PAQR4,BOLA1,FAM76B,SNAP23,RNF146,SAP30L,PDIA2,CAPZA1,CLDN6,CDK5RAP3,TNFSF10,FMO3,NEK9,MNAT1,FAM3A,STAC3,OR4N2,UBE2B,CSE1L,ACHE,IRF2BP1,FBXO3,AGAP2,STX1A,GUK1,NOSIP,SLC25A45,NR4A2,CD4,NME2,UBXN6,KCNF1,UBAC2,SFXN1,PPTC7,PCK2,RALGAPA2,GANC,ACO1,BEND6,PRMT5,TRA2A,SATB1,OR5I1,G0S2,KLHL32,SRGN,DRP2,DYRK1A,STC1,OR8K1,RAB31,INSM2,AIG1,NEUROD6,EIF2D,SLC25A20,TSHR,GTPBP2,EIF2AK2,LGI3,C1GALT1C1,COPS2,TRIM27,LIMD2,DEFB115,NXPH3,SSBP3,NSA2,TACO1,SNX2,NOL7,CAMK1,WFDC5,BCCIP,ERP29,PTTG1,IRF2,TM4SF1,NUDCD3,SEC63,MCAT,NOVA1,INPP5K,OR52W1,SUB1,TM2D2,NDUFB5,NELL2,CDC40,SCN1B,ARHGEF6,PCSK2,DCAF4,CYP4F12,CPE,SLC39A13,MYT1L,USP2,LRTM2,CYB5R1,GPHA2,NTF4,POC1B,DTD1,REXO2,TLCD2,TAS2R16,PACRG,HP1BP3,OSGEPL1,UTP15,MCM8,IL13,EIF4E2,GRM8,RIMS3,CAMK2N2,RMI1,DLAT,CUTA,ANKRD49,PNMA2,MT1A,CD38,UGT2A3,PLXNC1,PHC1,BLOC1S3,TAAR6,SELENOT,EPYC,GRAP,NOB1,TMEM184C,DCP2,MED17,BAG2,ZBTB33,GEMIN7,PHF12,MGAT4B,ZNF7,RNF41,XPNPEP1,DCAKD,PLP1,DCUN1D3,LMNA,PHF1,CD52,CYP3A5,IRAK1BP1,TIMM8B,TMEM74,EXT1,ALKBH3,JUP,DDT,CDC42EP4,EIF3E,CTBP1,MSRB3,FASLG,KLRD1,OR4N5,ZMYM2,SNX5,SLMAP,CFL2,BUB3,EXOSC4,GLTP,GNB1,CDC16,INPP5E,ASB8,ORMDL1,SOCS4,MED9,TREML1,CXCL11,MED30,GHR,SLC6A8,PYCARD,CUL2,TMEM160,VPS4B,OR7E24,FOXP3,LDLR,PPP5C,RBM42,RHBDD3,GSTA4,MAP2K6,MAD2L1,CA10,PCMTD1,RASGEF1C,TOMM7,LACRT,ANAPC11,SEPHS1,EMP2,LILRB1,OVGP1,EHHADH,GLRB,DNAJC1,HCLS1,GPX2,TRIM46,TRIM63,PAQR9,IL4,THAP2,TIAM1,FAM110B,STBD1,ZFP64,COIL,LSM14B,TUBB,STX10,SYCE3,SFTPA1,FAM50B,TRAPPC10,PSPC1,GNAI3,SF3A1,ZNF596,RING1,SFN,MCHR1,NETO2,SMARCD3,SSR1,AVPI1,RBFOX3,DISC1,CHID1,COX10,PHF23,CDK8,BSCL2,RNASEK,MAEL,MTX2,ELOVL3,CYB5A,TFG,DHRS7,CRB3,VLDLR,WDR83,VAMP3,CLVS2,KIF3B,HTRA1,LCA5L,MITF,HELLS,IKBKB,FAHD1,TRIM8,RPL13A,RPP14,TAGLN2,SYT4,WDR20,HRAS,PGM1,NAT9,HADH,CLEC9A,IKZF2,RPL8,PRKCQ,WASF3,MRFAP1,TFIP11,GABRG2,B4GALT7,VSTM2A,ZSCAN5A,SMCHD1,TRMT11,GTF2IRD1,CD1E,MRPL40,CNOT6L,TMEM88,CLCA1,FBP2,PPIA,ZDHHC15,MAP3K12,RSPH1,SOX3,RPS4X,TMOD3,COX19,NCKIPSD,CTSB,DEFB121,ALKBH2,RPS29,SKA3,LRTOMT,NFE2,LECT2,TRIM52,ACOT8,HNRNPA1,POGK,SLC16A4,RGS19,ENTPD3,RASGRP3,MGAT1,RCE1,MCM3,RNF115,CDC42EP3,IFIT2,SECISBP2L,RAB33B,MS4A7,HNRNPD,PDCD1,SLC25A11,PAFAH1B1,KCTD15,PSMD12,CCT7,CKLF,CHST11,HMX2,ICAM3,UNC50,NEUROG2,MTMR6,CCDC85B,SEMA6C,LUM,MED31,SH3BP5L,CELF6,FCGR2A,NAA50,RPL7,YTHDF1,TUBA1A,TERT,MKKS,SLC35B4,CISD1,MORC4,LANCL1,PIK3R3,SRC,CD2AP,KRTAP12-4,MPZ,VPS28,OR51M1,GNG13,TUFM,IDH1,IFNA2,RASL10A,METTL6,NLRP6,CHRDL1,PIP5K1A,PSMB6,ZCCHC17,PEG10,IZUMO1,DHRS7B,BAHD1,TRAF3IP2,TOMM20,PTGER4,TPGS2,IFNGR1,NUP50,RIMS4,NDUFA2,NMI,OSGEP,SCN3B,MOG,PLSCR4,LRRC57,POMT2,NDUFB10,PADI2,POLR2F,TMEM190,NSFL1C,OGN,SCPEP1,DHPS,RRN3,UTS2,NIF3L1,GNG5,TMEM14B,NTPCR,YBEY,MRPL10,IL15,CYP27B1,PNOC,TLE1,ARL6IP6,BTF3L4,HMG20A,ZNF668,CD248,RPL35A,RSRC1,SLC39A3,SLC25A28,CXCL12,FLCN,MSL2,KLHL12,IDO1,PPM1D,SERPINI1,TMC7,LRIF1,FTL,STIM1,GRPEL2,FLRT3,TNFSF13,ZRANB2,PCDH9,LIN7B,RIC3,DES,ARHGAP25,TCAP,EIF4E3,MYOZ3,FAM162B,GLT8D2,SPATA6,VTI1B,ARHGAP5,ZNF575,MRPS7,CCL20,UNC119B,TBC1D4,XXYLT1,RPAIN,GIMAP4,MORN4,GOLGA5,OSBP,DNTT,NDUFS3,HPGDS,OR9K2,RLN2,MED21,TWSG1,OCIAD2,SSRP1,PAIP1,PSMC1,LGR4,DYNC1I1,HECTD1,FGF10,TLR2,RERE,IL6,PPP1R12A,CCDC122,GRID1,TFEB,CES5A,HSCB,SYVN1,GABRB2,ARMC1,AURKAIP1,AKR7A2,FXR2,RPF1,LDHB,RNF126,TMEM182,FOXP4,FERD3L,MXI1,USP5,ITGAV,GPBAR1,TCEANC2,TM9SF4,NUP37,LRRC1,SLC1A3,SLC22A8,DRD1,SMAD4,FZR1,RILPL2,PPP2R3A,GPR85,FAIM,ELK4,ATP1B1,BAK1,IL1RAP,VKORC1L1,DRAM1,CNPY4,SMARCA5,PSME1,CYP2F1,PNO1,KBTBD4,FAU,CLVS1,AK5,RAB22A,SMC4,OR8I2,GTF2E1,TNNC2,FCHSD2,ISCU,OR5AP2,MOSPD1,ELAVL2,UBE2E3,TRIM10,SLC6A12,PIR,UBE2M,AGAP1,DDAH2,MATN4,ACTB,CNTN1,ZER1,CPNE1,GNB4,RFC2,TYW3,SNX18,LNX2,SOCS3,PTPN22,PDRG1,FOLR2,FNDC9,PPIH,DCUN1D5,CD1A,LPAR1,HSP90AA1,HDDC2,EID1,ZNF280B,MMP21,NFKBIB,CHCHD3,EPO,RPS13,CCSAP,RNF121,PGAM1,AP2S1,UGDH,PFDN4,SST,COMMD5,GABRA2,RSAD2,RAB30,TMEM208,NICN1,DNAJB2,PSMA2,GRXCR1,GGT7,EFHD2,NRBF2,PPIG,PPP4C,NAA35,GSTM2,UBFD1,TAS1R2,DAD1,ZBTB2,MFN1,NPY,PLA2G12A,CAMLG,CNR1,STX12,RP2,GZMK,TMEM199,FBP1,NLRP1,CNPPD1,ATP1A1,CRKL,TGIF2LX,PSMA5,AOX1,STARD13,B4GALT1,DNAJB6,DNAJC27,CD1B,LRRN1,GCC1,KDSR,AZI2,EGFL8,ARL15,ILVBL,NUDT5,NDUFA12,DNAJC25,NAE1,GSTK1,GTPBP1,KCNMB2,RPS11,TXNRD1,TNFRSF14,TMOD1,KATNAL1,UCK1,CDC123,GNAI2,GABARAPL1,CD46,TRMT1L,KCNMB1,MYCT1,ARL10,CBX5,FAM118B,COMMD2,SVOP,TM9SF1,MAGOHB,PEX5L,CD1D,PLN,MRPL52,MYD88,FCF1,E2F4,TMEM209,GFI1,GLYAT,FLRT2,PPM1G,CDC42EP2,DEDD,BOLA3,TMUB2,OR4K17,MAX,RHOB,HOXB1,NRSN1,LCMT1,CSNK2B,YIPF4,PROM1,VMO1,TRIM11,C1QL3,MRPS18A,G2E3,GLRA1,MTG1,RPL3,TOPBP1,QPCTL,RBM18,ARFGAP3,ARL4A,LITAF,LRRC4,MEF2C,DRAP1,DOHH,FUT1,RPRM,PLAA,BAP1,IL1B,GPR26,EXOC1,GPX4,RIMKLA,SEC62,FGF12,PHAX,FKBP10,BAALC,RHCE,LY6G6C,ANGPTL2,TMEM106A,SEC61A2,RPS27L,ELAVL4,TNNT2,GOLPH3L,COMT,TESK2,STK11,GPSM3,TP53INP2,SNRPD3,ZNF175,LAMTOR3,EIF4A3,DDX5,LAMTOR1,ADNP,RAP2C,TPSG1,UBN1,CYP17A1,FOXP2,UBE2F,RPS5,CCHCR1,SNAPC2,SLC22A12,CYTH1,CCDC71,SLC1A1,PDE9A,COG1,RPL10L,SCYL2,PHKA1,MBLAC2,ALG2,IRF6,RAF1,DNAJC10,RGMA,PRRG1,SAT2,GPNMB,GTF3C3,RNF14,DET1,OR51A4,ZNF330,KLHL7,MCHR2,CSTB,OAF,SLC45A3,CYTL1,NDUFA4,SYNGR4,PPFIBP1,HEXB,SHMT1,TRUB1,SNAI2,CALR,THBS3,DRG2,ADCY2,MAMDC2,TSG101,PKIG,MOBP,PATE2,MRPL51,CDK5,GNG3,SELENOF,MAP1LC3A,RAB13,OR10G2,RNF26,NDC80,SNAPC5,RPP21,CYB5R3,PLAC8,ZC3H15,DSN1,ODC1,SLC25A23,SFTPC,TOB2,YIPF5,PDSS2,SLC6A4,NME4,FNTB,DYNLT3,OR4N4,ZBED4,SP4,SDC4,CD79B,WASL,TMCC1,REP15,GOLGA7,BVES,RAB14,APOBEC3D,RAB5A,PC,NDUFB7,ZNF526,NDUFV2,NEK2,SSBP1,F10,KCNA3,TMEM31,PTN,ZNF507,STAT1,PAX6,EIF2S1,UGP2,LMO3,LMBRD2,MRPS33,DPP4,PRDX2,HEXIM1,CHRM1,MSX1,IL3,P2RY11,DLG1,KCTD9,RPN1,CD151,TLR6,EYA3,DUSP26,TMEM176A,ANAPC13,CNTNAP1,RNF39,PBLD,HDAC6,CHMP5,ASB3,AGPAT1,BTG1,ZMYM4,EIF2S2,CISH,GNA14,CXCR6,TSC22D3,NANP,USP14,TXNL4A,ATL1,SNCB,TPT1,RRAS2,FRS3,RPL35,POLR3F,RERG,OTUD6A,STOML2,TOR1AIP2,NUP153,MICB,RNF20,PPARA,COPS7A,GPR15,ACTL9,GTF2A2,ARRDC3,ZCCHC12,LRWD1,EEF1G,SLC25A17,NFYB,LILRA1,PDE1A,DAPK1,KCNQ5,TPBG,STXBP6,PRPF31,BMP1,NR1H2,MMADHC,TTC1,SYT2,SPOPL,TMEM95,LEPROTL1,ST6GALNAC3,TBC1D24,EDNRA,YWHAB,THY1,PSMD14,SLC25A44,ZNF692,CDSN,SESN3 |
| 7.393e-20 | -44.05 | TP53 (tumor protein p53) | protein interactions | 7157 | 2268 | 823 | 19454 | 5460 |
WDR12,MPHOSPH6,HNRNPD,RB1CC1,HMGA1,PLAC8,HNRNPA1,EGLN3,NABP1,PSMB4,PPID,RPN1,JPT2,POLR2C,JUN,RPL29,ACTN4,MAPK10,SSRP1,MSL2,UBE2A,RPS27A,ZYX,SCYL2,NEK9,SLC25A5,BAG2,BRCA1,YWHAZ,TM9SF4,NFYA,HMX1,CAPG,HSD17B3,TUBB,AIPL1,MAD2L2,UBE2V2,S100A6,IFT172,RPS9,POLR3B,VAPB,SLC25A3,ANXA7,FKBP10,AGTRAP,RADX,YTHDF1,TBC1D24,PRKD3,ATP2C1,TERT,TXNL1,NEUROG2,MUL1,BRD3,FOXP1,ID1,FAM133B,DCUN1D1,MRPS23,MDM2,CDK9,EIF4E2,TOPORS,CCT5,EXOSC8,MAP2K3,HUWE1,SMN1,PTGES3,IGF1R,KLHL15,ZNF177,NRP1,TAF5L,NDN,ZBTB17,PDCD5,UBE2L3,EIF2AK2,MET,STAMBP,UBA52,NFYB,JMJD8,FTH1,FBXW7,IRF7,CXXC1,DAD1,PIAS1,DVL2,HELLS,ARHGAP5,RPL6,LAMP2,DDX50,FAM241A,XPO1,SUMO3,RPS10,FUBP3,RPRD1A,STX5,FGF10,PDHA1,NIM1K,TUBB4B,TAF10,APTX,HGS,EEF2,TUBA1A,NAB1,HNRNPF,PSMA1,PELI1,CCAR1,RPL31,S100B,SETD4,TRIM21,EWSR1,FBXW11,CCT2,SERPINH1,ZMPSTE24,CDKL2,LDHB,HNRNPC,CHST9,MYC,UFD1,PSMD1,APEX1,POLR2B,DLST,CMTR1,TRMT11,LMBRD2,CSNK1A1,EIF4B,NUFIP2,PSMB3,UFL1,HERC3,SF3B1,GPHN,RPL24,H2AC4,TSNAX,MAP4,TAF9,DPP4,E4F1,TPM3,GAPDH,TMED9,PLG,FZR1,MRPS9,SSBP1,ACSL4,CDK8,SURF4,FURIN,TP53,IMP3,AKAP12,NEDD8,PDE12,PHF1,GPX2,BHLHE40,DHX9,SOS2,CLPB,MECP2,CDKN2AIP,IGF2BP1,DTL,AKT1,SMARCA5,PLAGL1,CTSB,THAP8,DAPK3,IDE,ACVR1C,CDIPT,CALML5,CSNK2B,RNF187,WWP1,HBB,RAG1,CSNK1G3,KLF4,DYRK2,TFIP11,CXCL8,AGO1,WDR3,BCL6,BNIP3L,LIN7C,DDX46,BAP1,STOML3,OR51M1,PSMD10,BCL2L1,NQO1,LYZ,HR,PRDX1,RPL7,SPTAN1,MPP1,OCRL,LRWD1,PHB1,DNM2,HP1BP3,RPLP1,TSG101,OTULIN,RNF126,G3BP1,RFC3,PPWD1,CDKN2C,ATF3,RPS24,UBE3A,GPSM3,JAK1,MYO6,MCM8,CUL3,SCN3B,MCM3,ZNF668,RBBP4,RPL19,FAU,RPL37A,AGGF1,IL1A,G3BP2,FOXP2,SLC35F2,CCDC86,ESYT1,SLC2A1,TOPBP1,DNAJC7,PKIA,TOP1,AIFM1,SEC23A,SRP72,YTHDF2,SERPINB9,THAP1,HINT3,MAP1LC3B,SLC29A1,HSPE1,MDC1,EIF3E,OLA1,RNF20,SLC25A10,RING1,TADA3,TXNIP,SEC13,GMPS,AR,ATP5F1A,CD47,TXN,OGN,SEC63,TECR,PELP1,TRIM24,PRKRA,HSP90B1,GHITM,P3H1,CDK1,TOX4,SNRPN,TPT1,WDR83,BRINP1,HACD2,EIF5B,SLC5A6,AATF,SIRT7,CCDC106,SQSTM1,MAVS,FKBP4,IKBKB,YWHAB,STK4,TCP1,TNIK,S100A8,ZHX1,CORO1C,MTA2,TOP3B,STBD1,KIF2A,RPL28,RBM3,PABPC1,GTPBP2,DNAJB6,PAPOLA,FBXO22,PSMD6,PSMD4,TOM1L1,GSTM4,NFKBIA,ANAPC2,PHKB,UBAC2,DMTF1,RPL27A,YIPF5,DHRS4,MSX1,HNRNPA0,ZBTB5,XRCC5,RFC4,LCN1,HSPA8,COX17,HDAC5,BECN1,SNRNP70,TUBG1,RPL10A,ZNF24,EDEM1,ABHD16B,PPM1D,CSNK2A1,KLF9,SLAIN2,SYNCRIP,RHAG,MCL1,NFE2L2,MAD2L1BP,TP53I3,PHC1,PSMC3,CDK4,ZMYM4,H2AX,KPNA2,RBCK1,MNAT1,IDH1,RPL3,SLC16A1,ABCE1,EIF3G,SNX5,PTTG1,ATP1A1,MED22,SUB1,FOXA3,MGST2,TNFAIP3,RPL10L,NR1I2,ROCK1,PPP1R10,PAFAH1B3,DCLRE1C,CREB1,EIF2S2,ZNF326,WRAP53,LDHAL6B,PRKCA,UBE2M,SUMO1,SPTBN1,SMYD3,CFTR,GTF3C4,CCNH,MRPL41,UBE2K,KDM1A,HSPA5,ZC3H15,PRDX6,PPM1B,MTRF1,ZNF207,HYPK,WDR44,DHX15,RPL8,GLRA1,KRT8,RPLP2,TYMS,RAF1,VDR,CSNK1E,PPP2R1A,PIWIL1,ASF1A,DHX16,UFM1,KIT,ZBTB16,COPS4,FOXP4,SACM1L,KLRF1,GTF3C3,HNRNPA2B1,GADD45A,HECTD3,PCNA,SETD7,HSP90AA1,CNIH4,BAX,ACO2,BMP1,MED17,ACTB,TAB1,CD40LG,SPCS1,PRDX2,USP5,PRRC2A,ERH,FAM91A1,ACKR3,ZMAT2,CRYAB,FOXS1,USP39,ELOVL1,TOR1AIP2,ACTL6A,MAPKAPK5,CDKN1A,CMTM6,NOP53,AZGP1,PSMA3,ECD,MOV10,ERCC3,H2AC14,TP53INP1,HM13,TSC22D3,MRPL24,ACTA2,SMAD3,RPL12,HRAS,CCDC3,RB1,TES,HINFP,B4GALT7,VRK1,VPS16,RNASEL,EGR1,TMED1,NKRF,PPP1R12A,TGIF2,RPL23A,SMAD2,RPL26,PNP,UBB,FERMT2,CCNF,ODR4,ALB,MSN,GTF2A1,TRIM27,RPL26L1,LIMS2,SF3A1,GABARAPL2,CCNA2,CDK7,ARMCX5,NF2,SLC7A1,TMUB1,RPA3,SPCS2,TCEA1,RTN4,GSTO1,DDX1,CBL,WWP2,ZCCHC10,IFI16,DDRGK1,YWHAG,SUMO2,OSBP,SNRPA1,SNRPD3,HNRNPL,DBR1,HSP90AB1,CCT7,SIN3A,WDR82,SMARCB1,FOXJ3,RPS7,H1-3,COA1,RPS4X,LSM14A,ABCF1,RNASE4,CDK5,MRPS25,MDH1,RPS26,COP1,SFN,CREBBP,TESPA1,BTF3,TAMM41,MATR3,PSMB6,PRMT5,ZMYM2,PACRG,AKR1A1,LAP3,SYK,TRA2B,TMEM106B,SMARCD3,MIA2,DDX5,AKAP8L,USP3,CD81,MIF,PHYH,SLC38A2,UBE2N,ALYREF,CDK6,RAP1B,ADD1,NUPR1,KIF1C,GNPNAT1,GASK1B,ESS2,HNRNPK,RPL17,MEPCE,ZNF451,UBE2H,RPL7A,TRIM32,RPGRIP1L,DAPK1,PSPC1,SEC61A1,TRAF7,SUPT7L,TRAM1L1,GTF2H4,POLR1D,CDC42,STK38,HDAC3,NME4,RPS15,TRIM3,NBN,PML,RPL27,SMG5,GFM1,RNF34,TRAF6,CSTA,FXYD6,RPL23,PPP3CA,TRIM8,FAM174A,ZBED4,TAF7,TRA2A,SNX2,THOC2,COPS2,GTPBP1,RBPJ,KHDC4,E2F4,TXNRD1,GTF2E2,ASPM,ZBTB14,KCTD17,TRIM37,RBBP7,MCM6,ARGLU1,ZC3H7A,LMNB1,FAS,RIT1,SP1,FHIT,CUL2,MCM4,RNF40,UMPS,MB21D2,RAN,SERINC1,CDC7,ADNP,PPARG,MED23,WDR77,GK2,IDH3B,SUPT3H,SKP1,NT5C3A,HADHA,SAT1,PSMD7,CRBN,MED21,SSX2IP,BAK1,ZMYND11,MPG,GTF2E1,PRNP,KCTD15,ZBTB2,RCHY1,HACD3,PWP2,UBE2B,APEH,HOXD12,PPP4C,JCHAIN,SMAD1,RPL15,LBR,ING1,EEF1A1,BACH1,THRAP3,MSH6,RPS13,GABRB2,TEDC2,SPSB1,PC,PIP4K2C,CHORDC1,TADA1,EPHA2,STK11,CAP2,PPP1CC,HPCA,LDHA,EAF2,SCAMP2,STUB1,SENP5,PTEN,UBE2I,SNX12,GANAB,CAB39,SNAI2,JUP,LMNA,PAK5,RPLP0,CCL18,CCND1,RPS14,PSMC4,HMGB1,RPL4,GTF2I,DGCR8,POLDIP2,SYVN1,HSPB1,DRG1,CIAO3,SIVA1,PPIB,PPFIBP1,DYNC1I2,MPDU1,HOMER3,SRSF1,MAGED2,RAB4A,RPL18,SUPT5H,RNF39,CRTC2,SATB1,TOP2B,CCT8,FBXO11,FTSJ3,POMP,SLC38A1,COPS7A,PCCB,HECW1,TCEAL1,CAVIN2,GTF2F1,TLR5,PLAA,CTBP1,FBXO42,EMC1,FOS,EP300,SEC14L5,KCNJ10,USP15,RPS2,XAF1,MZT2B,COPS5,RPS16,ARL6IP5,SSMEM1,STT3A,GTF2B,TRIM45,SST,RNF128,TMEM165,TFCP2,TFRC,TBC1D4,TSPAN3,GFM2,ZNHIT1,TMEM205,MRPS18B,STX18,TRIM23,RAP2C,RPS17,BUB3,BCCIP,SRC,SMURF1,ZBTB33,LIG3,RPS3,MRPS28,ING2,PSMC5,BORCS5,ZNF267,EIF2B3,CSNK1A1L,RPA2,RPRD1B,ACACA,HECTD1,STAT6,HEXIM1,ING5,CAPN1,CREBZF,TRAM1,MARS1,EXOSC4 |
| 7.525e-20 | -44.03 | DDX21 (DExD-box helicase 21) | protein interactions | 9188 | 686 | 302 | 19454 | 5460 |
FTSJ3,CHTOP,ATG3,H1-10,RPS26,NSA2,MYC,HNRNPAB,HNRNPC,RPL39,MATR3,SNRNP40,RPL10,VDAC2,DLST,SURF2,MIRLET7B,PIH1D1,RPL27A,MTF1,FBXO42,ZC3H14,UFL1,TRA2B,HNRNPA0,SSR3,STAU1,RANBP10,SAP18,DDX39B,SNRPA,RPS28,HSPA8,SF3B1,RAB5A,DDX5,MIR31,MIR221,ARMC8,DRG1,MIR140,IFI16,LAMP2,BAZ1B,DDX50,RPL6,WWP2,MIR143,MIR29C,DDRGK1,HNRNPL,RPS10,SUMO2,MIR9-1,LYAR,MACROD1,EED,MIR214,SMNDC1,RPS23,RPL18,APTX,TRMT1L,SOX2,MIR222,DNAJC25,RPS7,MSX2,H1-6,KRAS,VDAC1,MIR155,RPL28,HNRNPDL,RPL31,PABPC1,MIR9-2,MIR206,MECP2,SPOP,RC3H2,IGF2BP1,ATP1A1,UBE2H,CDKN2AIP,RRP7A,RPF2,SMARCA5,RPL7A,SUB1,FBXO44,KCTD9,SMURF1,SRPK2,PSPC1,RPS3,ZNF330,FGFBP1,RBMX2,RPA2,ZNF326,HEXIM1,MIR21,MIR7-1,MIR34B,AGO1,FGF13,RPS15,MIR29A,MIR107,RBM23,RPL27,MIR10B,THUMPD1,RNF113A,SNRNP70,H2AC4,KPNA1,AKAP8L,RPS2,RPL10A,RBM17,CSNK2A1,E4F1,RPS16,DNAJC1,FZR1,MIRLET7G,MIR429,DKC1,RBM42,CDC5L,SURF6,SYNCRIP,RPL32,ALYREF,TFCP2,IK,DNAJC2,RBM34,NUPR1,STRBP,KBTBD4,TP53,H2AX,KPNA2,IMP4,HNRNPK,MEPCE,MIRLET7C,RPL17,MIR16-2,SNIP1,MAP1B,MIR200A,RPL3,DHX9,MIR9-3,ZCRB1,BRCA1,LMNB1,MIR363,RPS5,ILK,RIT1,CUL3,MIR98,RPL35,RPL7L1,MIRLET7D,RPL19,ERH,FAU,ZNF22,EIF3K,RSRC1,RPL37A,RPS9,APOBEC3C,USP39,H1-5,HSCB,UCHL3,G3BP2,MIR106A,CCDC86,DDX23,HNRNPD,MIR1-1,RB1CC1,ATG7,HNRNPA1,TRA2A,SPTAN1,CCAR2,RPL7,RPL8,RPL9,PHB1,MIR7-2,HP1BP3,RPLP2,MIR141,EZH2,CHMP4C,RPS11,POLR2D,SART3,RAF1,MAK16,JUN,NUP153,LGR4,G3BP1,TRIM37,SRSF4,RPS27A,SSRP1,TRIP4,HNRNPA2B1,FGF3,ARGLU1,RPS24,SRSF7,MIR145,IVNS1ABP,CASC3,MAPRE1,RUNX1,RPL26,PPP1CC,USP14,NDN,MAGOHB,RPL13A,RPL22,DEK,CCNF,MIR16-1,EIF4A3,PRKRA,TRIM24,UBE2I,PTEN,RPS20,LMNA,ZCCHC17,METTL14,LSM2,RPL26L1,RPLP0,MACROH2A2,RBFOX2,MIR1-2,NPM3,MIR7-3,RPL4,FBXW7,NHP2,PIAS1,AATF,BRIX1,RPA3,MIR205,SIRT7,PRPF4,PNO1,KIN,PRKCB,MIRLET7I,MIR34C,MTDH,PPIH,MIR34A,MOV10,GRSF1,HDAC6,TOP1,THOC1,POLE3,NCBP2,CDK9,MIR106B,SRP14,KRR1,PRR3,MIR25,TES,MIR17,LLPH,MIR20A,ILF2,MIR15A,MIR200C,RPL15,CTNNBL1,HUWE1,VRK1,THRAP3,NKRF,ZC3H11A,RPL23A |
| 9.226e-20 | -43.83 | central_nervous_system-brain-glioma | COSMIC cancer mutations | central_nervous_system-brain-glioma | 15470 | 4584 | 16828 | 4835 |
JAKMIP1,GPAA1,TLR3,IDH3B,GRM2,CTNNBL1,CYP11B1,SENP5,GNRH2,CHDH,FAM8A1,NCR3,ITK,EIF4H,MYL12A,CYP39A1,HSD11B1,SWAP70,SNAPIN,KLK3,SLC30A5,MRPL50,MRPL24,ZNF304,IMMP2L,SLC35A1,DHRS4,ENY2,RAG1,FAM78A,PPP1R2,MIOS,RMND1,SLC38A9,OSM,IL15RA,TRIM23,NAIF1,NHP2,P2RY1,STRBP,ING1,IRF1,OR8B8,UBE2D3,ATP6V0E1,CCT2,ARMCX1,UBE2A,PRPSAP1,TCP11L2,GRPEL1,ELMO1,FGFR1OP2,GABARAP,GAL3ST1,OR4D11,CASK,LTBR,LMO4,CLU,ATPAF2,KIAA0232,NRP1,NCKAP1,CDK5R1,GLUL,CNIH4,XAGE5,SEC14L1,ZNF319,ID4,ZNF397,APOBEC3A,CCR6,ZMYND19,SLAMF9,TAAR1,TMUB1,TRIM3,C1QC,POLR3H,ZNF207,TMEM219,ATP6V0B,EDF1,LYPLA1,LIG3,RPS14,UGCG,MEAF6,SLC17A5,SLC25A31,ZNF671,TRIM32,SDR42E1,UBR7,PDIA6,PRIM2,SNRNP27,CD99L2,DOK4,ARHGAP1,KLK9,PLA2G5,KLHDC8B,RNF141,GFM2,MRPL23,GDI2,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,E2F6,MRPL13,MDM2,MGP,EHBP1,AK2,SOCS5,GALNT1,CCDC69,PSMA3,TMEM156,GSTO1,NUDT3,B9D1,RND3,CNP,TOM1L2,GNRHR2,UST,PFDN5,EXOC8,LYAR,CDO1,ASMT,CCNI,PPIL4,RAB11A,DKK3,IL20RB,SF3B4,DPP10,PRRC2A,CRABP2,FGD2,APEH,AKT1,DLX1,COMTD1,FNDC8,TLR9,FIBIN,SNX20,L1CAM,SLC25A21,RBBP7,PGS1,RMND5B,PTPN1,SETD5,HNRNPC,NFIL3,TRIM37,HECW1,ZBTB38,GALNT12,ARFIP1,PPARG,SPR,ARMCX2,SIX5,TRIM21,ACTA2,RBM17,PCDHB8,HEY2,RFX4,FRMD8,PKNOX1,ADRB1,ZDHHC14,LRP12,NPY2R,SPTAN1,SLC35E3,RNASET2,TRAPPC1,FAM199X,CLDN11,NIPA2,RABL2B,PAEP,GHITM,RPL15,TUBG1,CCDC47,SCFD1,TTC4,BUD31,SRP54,TMX4,CAMK2G,PRMT2,TACR3,CIB3,CD200R1,PPP3CA,CRYGB,KCNJ11,RCVRN,FAM89B,PEX3,CCDC127,PYGM,OR4K1,SHC1,HCRT,CAMK2N1,FGFR1,ANAPC2,FBXO32,AGK,SBK2,SORD,ENPP4,CCT5,PSMB5,MCOLN1,FKBP14,IDH2,RAB18,IMPACT,AGER,CD58,PRPF4,ZNF593,ARMCX5,KBTBD2,GSTO2,GNG7,CTNNBIP1,ATF4,PIWIL4,CSNK2A1,KPNA1,RARRES2,LSM3,AFTPH,OR4D9,RS1,KIT,P4HA2,JOSD1,SUPT7L,BTF3,MMP9,CDC73,ZYX,UBAP1,LHX2,DYNC1I2,S100A6,CYP27A1,TMIGD1,DNAJC5,PGK1,VRK1,ROPN1B,MYH2,SLC7A9,ALKBH4,HEBP1,PACSIN3,SYN3,ZCCHC10,GPBP1L1,MX2,AAMP,LYG2,MFSD6L,ATP6V1G1,MEST,FZD4,MTPN,WDR77,SERPINB10,TSEN54,ZNF24,FBXO42,TMEM215,LBH,JAK1,NKX3-2,CCL19,MAGOH,TBC1D10C,GTF2E2,MLF1,PSME2,AZIN1,FGF1,AZGP1,INO80C,ABCB1,HBE1,KTI12,CDCA3,RAB3B,SMAP2,DEFB116,TNFAIP8L2,DHRS3,NDST1,OPA3,TAC1,IGFBP4,NPVF,AKR1C2,LMBR1L,NQO1,IPP,SPATA2L,TBCE,CD3G,PAOX,BRMS1,CDKL2,KIF1C,GAS8,CHRNA7,HEXA,OCEL1,ADAT1,BRI3,RBM23,TMED1,OXNAD1,CCL21,NDUFA5,KCND2,CXCR1,NEDD8,FGF17,HBB,TRMT6,PTCRA,TIGD7,FBXO30,POLR2I,CD2,ACAA2,UCKL1,RAP1A,WWP2,RABAC1,IL34,DFFA,ST13,LPXN,RASGRP2,STX17,LEPR,WNT7A,CXCL1,XPOT,PDIA3,FRA10AC1,EIF1AD,APH1A,NDUFB8,ISYNA1,KRR1,NLE1,SNAI3,PELI3,CDC37L1,RPRML,MSX2,RPL37A,SERPINH1,STAMBPL1,SIPA1L1,PGBD2,HSPE1,CLDN14,ZKSCAN1,HSPB1,KCNA2,B4GALT6,LHFPL1,OR6M1,NUDT16,GXYLT1,DHX16,TRA2B,SOX21,RAB4A,HADHA,LEAP2,ENDOD1,ANKIB1,CIRBP,CXXC5,OSR2,GALE,EIF2B5,SH3GLB2,WBP2,GTF2A1,FUT8,SPOCK1,PHKG1,LASP1,UTS2R,NEK7,CCL25,GNMT,AQP4,CREBL2,TXNIP,FURIN,SLC39A9,DHX9,IL23A,PSMD6,EIF4EBP3,WDR37,ZSCAN1,OR51S1,PRCC,GSK3A,PCDHA5,SLC20A2,NUBP2,LDHA,PFDN6,UBXN10,RC3H2,DNAL4,ATP2C1,FATE1,THOC1,ABCC5,RANGRF,NUDT19,TF,RNF103,CREB3,XPO5,SURF4,INTS10,EXOC2,XPO1,EEF2,THRAP3,EFHC1,SLC25A32,GJA10,SLC7A4,ZNF513,ZMYND11,APOBEC3C,GPR162,RNF187,MIA2,BACH1,KIF2A,INPPL1,CRYBA2,DEGS1,ID1,PTDSS1,ARMC8,ENTPD4,SLC35A2,NPTN,FCAR,CCDC42,CYC1,POU1F1,CD164,PPIB,CDKN3,BPGM,PRKD3,CYP4F8,SLC5A6,DEK,NLGN2,SCAMP2,NUP107,OR52M1,SPEF1,FABP5,MRGPRX4,PGAP2,CTSD,RBCK1,MRPS25,NOP58,AKR1A1,NFE2L1,STX8,BATF,TOLLIP,DUSP1,TGFB1I1,NFYA,FAM200A,S100A10,CACYBP,CTSK,URM1,CETN3,PWP2,MTAP,RAB3C,DCAF8L2,AP1G2,NDNF,CHST9,CPT2,ANP32B,COX7A1,FBXO9,CCND1,OR2W1,RPGRIP1L,ACOT13,TMED3,WFDC13,SETD4,LCN6,RHCG,SCG2,ARHGAP21,BMPR1A,FAF2,KLF10,AP3S2,MPHOSPH10,TMEM33,S100PBP,MRPL47,ENPEP,NAB1,FGF13,PRKX,PROX1,SYNGR1,LSM6,RTP4,USP38,ZNF174,SLPI,CERK,USP39,ADCY3,SNRPD2,CWF19L1,CDK6,ESR2,DCAF5,CYP2D6,INTS12,SOCS2,RAB8B,CTNNB1,CLEC12B,SFTPD,MTMR12,DUOXA2,TRAF7,MMACHC,TNFAIP3,RAP2B,ABHD16B,RRAGA,ETV6,TAPBPL,FYTTD1,NOL4,IQSEC1,SIRT7,POLL,NONO,MAK16,ALDH1L1,TSSC4,H19,SPRED1,SNAPC1,SNTA1,GPR37L1,NDUFAF2,EMC4,GFOD1,SIVA1,OR2A2,EIF4EBP2,TCP11L1,SOST,SV2B,HPCA,ACAP2,MAFG,SCD5,LHFPL2,HNRNPK,PAFAH1B3,PRKAG1,NFKB1,POMP,RPL26,OS9,MRPS28,RIOK2,OAT,CLDN22,EGLN3,FOS,DYRK2,YPEL5,PPID,CCL8,RFTN2,TPPP,RB1CC1,CAPZA2,SLC35E1,FANCG,STX6,OR2A25,PLA2G15,RCBTB1,GGCT,ATP6V1C1,HNRNPA2B1,S100A8,HIRA,CD47,TMEM50B,IFNG,JUN,WWP1,CBLN4,RHOJ,PTGER1,SFT2D2,RAB23,CMAS,CCR3,OGG1,ZNF687,OPHN1,SUMO3,RNF167,FAM107A,RAB33A,CRYGD,DNAJC8,PPDPF,TNFSF18,CHI3L1,RNASEL,TOMM40L,EIF3J,FERMT2,GIMAP2,GNPNAT1,UTP23,TNRC6C,SPTBN1,KLHL15,TRAM1L1,SESN2,PLAGL1,PAPOLB,RFXANK,CHST1,MPV17,EHD1,PPP1CB,TRAM2,GCA,RABL3,UPF3B,ISCA2,ZNF576,KRT7,PLEKHA8,GJB2,WDR3,MANSC1,NUS1,SRP14,TMEM106C,KCNK10,SLCO1A2,TMCC2,ZNF609,APLN,SYNJ2BP,ACP6,TMEM164,ACTR2,CRYBB3,OR4F6,PTRH2,FOXS1,TAS2R5,FMO2,TMEM177,RBM12,RAN,RPP25,SQSTM1,GLIPR1,RNF122,KIAA0408,BICD2,SERPINA5,CREB1,KIAA1191,CCL17,OR2H2,PAFAH1B2,GTF2F2,DLG4,KCNH1,POLR3B,PGR,HAND2,BRD9,HSPA14,CXCR4,NPY5R,MT2A,PPP1R16A,ATP1A2,PXMP2,CYB561D2,GMPPA,SLC7A14,DDX42,BNIP3L,TUSC3,SPRR1B,RPL6,CLDN8,ADAMTS1,CXCL14,HIGD2A,TEX12,TOP3B,ZCCHC9,SLC43A2,TMEM91,DDX4,KLK5,LIX1,CAB39,LRRC24,GRIA2,MRGPRX2,CPSF2,CDH8,TMEM14A,GDE1,TCEAL7,PCGF3,GPX5,MOV10,UQCR11,GLT8D1,NGB,MYEF2,PNPLA8,TAF5L,GYS1,SLC23A2,ROGDI,PGM2L1,PIWIL2,SOS2,AKIP1,SDHAF2,CLIC2,MED11,PPFIA3,OTUD7B,RBFOX2,FOXN2,GK2,CDKN1A,SLITRK2,ELSPBP1,STX18,ORAI3,HMBS,CD2BP2,TDRD7,CCDC65,LDHAL6B,AMY2B,NDE1,RBMX2,OR5L1,RGS5,RPAP2,INHA,RAB1B,HRH3,ZBTB45,ABHD13,UBE2D1,LY6G5C,SLC4A8,SNIP1,FAM168A,ACTL6B,LYNX1,RPL23A,TMEM59,IL6ST,TIMP1,DERL2,TXNL1,MLF2,PLEKHJ1,PPP2R1A,MRTO4,PTHLH,SLC25A4,SMAD3,EIF4B,RAB5C,PNP,PCDH19,WEE2,AP1AR,TIMM10,STK38,CSTF2T,FBXO25,PSRC1,IFI35,C1QL1,CAV2,FOLR1,RAB37,SLC6A11,PDYN,ZFP1,B4GALT3,CD226,VPS33A,SACM1L,CRBN,TRAPPC6B,VAMP2,CCNF,RAB2A,CTNNA1,GPIHBP1,WDR44,BEND5,SNRPA,CMPK1,OR10G7,ISG15,ACADSB,SNX24,STAT6,PHYHIP,WIF1,FN3KRP,DYRK1B,AMT,RAB9B,EZH2,ARCN1,INPP4A,KCNIP3,CD274,EIF3K,B3GALNT1,CREB3L4,BCAP29,ZBTB17,FABP7,RINT1,TSPAN5,OR10G9,BZW2,SPECC1L,NAT2,KHDC1,LHFPL4,CDKN2C,COX4I2,TMSB4X,TRIM5,EIF4E,SSU72,IGBP1,AKAP12,RAB40AL,DDX39A,SNAPC3,SNCG,BLOC1S2,TFE3,DEFB114,MT1M,IFNA10,PELP1,ITGA6,CSNK1A1,COMMD8,TSPO2,OLFML3,GOLGA7B,EFNB1,RNF113A,SH3GLB1,PREPL,THTPA,UBE2V2,IL10,RPLP0,RTKN,NTN4,PHYH,FUT9,LMNB1,BECN1,TES,CCDC25,ADO,CALHM2,GMPPB,HSPA8,SLC19A2,CBR4,VMP1,CHMP2A,OSTM1,EMP3,TMEM204,PROS1,GPX3,B9D2,EWSR1,ZNF592,MTRF1,ELP3,YAF2,CIB2,ACSL4,TGFB3,TRIM24,MRFAP1L1,ABHD14B,MRPS16,EED,NME1,DUSP19,RGS2,STMN2,MBD5,KCNMA1,BCL10,NOS1AP,PDHA1,ADPRH,KCNK13,RBM7,TRAF2,BRCA1,ABHD4,PCDHB1,NR1I2,CNNM4,DPY30,CDK4,NPR2,STOML3,TSN,STAU1,SERINC3,SLC41A3,TMED7,DNAJC3,RNASEH1,FKTN,KLK6,ST3GAL1,SOX2,CSNK1A1L,DERL1,IL18,UQCRH,DPEP1,PRKAB1,STXBP1,PAX9,KLC2,CD36,IRF3,MTHFD2L,PYROXD2,MRPS21,LRP6,TAS2R40,RAC2,STK24,LCA5,ST3GAL5,POR,CEP97,ZNF501,IFRD2,PARP11,SLC32A1,SAT1,R3HCC1,CSGALNACT1,SMU1,SLC35D1,COL1A2,RMI2,PTS,TOR2A,AMIGO1,JPH4,GTF2H2,MAP3K11,MBL2,EDEM1,GNG2,VAMP5,METTL14,CRTAP,UHMK1,ANKRA2,ADIPOQ,ALKBH5,ERH,NDUFAF4,CRYBB2,AKAP14,CCNB1,CTDSP1,FAM162A,METTL2A,CLDN1,ABHD6,TFCP2,PRPF19,CREBBP,GPAM,LDOC1,PDCD4,RDH10,HTR1F,OR4Q3,POPDC2,GPX6,TGIF2,GREM2,RPLP2,FAM98A,ACBD7,CDC42SE2,TRIM54,ACAT1,TMEM184B,KDM4B,ZNF287,RAB3D,CLDN4,SLC13A5,LAMB2,NKIRAS1,OAS1,GIT2,SDF2L1,RUVBL1,GTF2B,CXCL3,NRSN2,TMEM144,TOP1,BCS1L,SNX17,APOO,GPR137,CYP2C18,NDUFS8,MYO6,OPRK1,GCNT3,PGPEP1,F9,NKX3-1,TOM1,BCL7B,SEC61B,GPR65,PAPSS2,TCF23,CHGA,EIF2B3,DNAJC22,HTR5A,TMX3,CDKN2AIP,RGS7BP,SFRP4,RER1,FCN2,FUNDC2,MRPS23,ZNF862,ATG4A,SYP,CSRNP1,POLE4,HSP90AB1,ISG20L2,GPHN,IPO8,TMSB10,ARMC7,ATAT1,CIDEB,TMEM123,AIF1L,CCR2,ZC3H7A,ZBTB5,DSTYK,DDX50,SLC25A10,HINT3,VRTN,GTF2H5,RPRD1A,STK4,BST2,PPP2R2C,CYP1A1,ST8SIA5,PLS3,SLC22A17,TNKS,IL1R2,TMEM41A,ACVR1C,FAM181B,NKIRAS2,STUB1,PIP4K2C,KLF9,ST7,AVPR1B,SRSF2,GSTA1,UBLCP1,SERPINB1,TRAK2,TEX264,SNRK,BTN2A2,UBL5,CSH1,IFNB1,CCNH,SEMG2,KIAA0513,MNS1,POLB,POLA2,UBASH3B,TOR1B,KANSL3,SPSB3,ABCG2,LTA,MRPS9,FAM83C,MTF1,PTH2,MSTN,RPL27,PPP1R1A,PRICKLE2,RNF148,CLDN9,DIO1,SLC16A10,VGLL2,SYNCRIP,SLC35F2,TRMT112,USP16,LTB,PFDN2,TCEAL1,HARBI1,TMED5,HMGCS1,SLC25A12,AK3,CLCN6,RPL32,PSMA1,DDRGK1,SHOC2,HDHD3,SMPD2,ATXN10,NCBP2,TBC1D13,ASTN1,SOD1,DTWD1,REN,CCR1,VEGFA,FAF1,DECR2,AVL9,IQCK,TP53INP1,NOTCH2,NAPA,SOBP,PTPN11,TM4SF19,CRAT,GNPDA2,TMOD2,POLR2B,TSNAX,GTDC1,UBIAD1,LRRC61,DHRS13,PARL,FBXO22,REG1B,GPM6B,SLC7A8,RFC3,ATP6V1A,ACP5,HLF,SERPINC1,TMEM59L,EGFL7,DENND2D,COPS7B,KLF4,OR4D2,OR10A6,ACBD6,RNF34,PREB,NFKBIA,NPW,TUSC1,ATG7,TAF10,PRDX1,FAM53B,TRIM68,ETF1,LRRC8B,VGLL4,DNAJC19,SCML2,FCGR1A,CCNY,CHKB,GPR176,PKP4,CLDN12,ELF5,OTOS,CNOT2,CRHBP,ERAS,GSTM5,ZNF326,PLEKHO1,MYBL2,ASB7,PRKACB,APOBEC3H,LANCL2,GLRX2,ODAM,KLF1,VDAC1,FEN1,CLPB,ADD1,CLEC2B,CBR3,SEPHS2,JKAMP,THOC2,STARD4,NR2E1,DROSHA,FLOT1,ORC6,SCNM1,MCM4,FAM177A1,DCTD,SLCO2B1,CX3CR1,IGF1R,CHMP4C,CEP19,SOX14,PDAP1,KLHL22,UBP1,MAVS,CD1C,UMPS,CDCA7L,SS18,MRPL22,HOXC4,UPK1A,EPS8,RFXAP,CER1,POLR1B,CHCHD6,SIAH2,FCGR2B,NUDT7,IFIH1,BIRC2,MTM1,PMM2,PRMT6,MPDU1,VAMP8,TMEM70,TTL,TIMP3,PRSS12,PPP3R2,PPP2CB,FKBP8,GABPA,KLHL24,SMAD1,AQP2,CLEC18A,ZNRF1,CHST13,IL2RA,PPAN,RCL1,SF3B5,SLC2A3,FBXO7,RABGGTB,SEMA4C,STOM,CTTN,VAMP7,SPIN3,RPL23,CLLU1,CEBPG,TGFBR2,TNFRSF1B,CDNF,ASZ1,CYP2C8,METTL22,USP3,CAPN1,OR8B12,PPM1K,CCL2,LLPH,GSTP1,IFI6,AR,LAMP2,FAM43A,NLRP9,RNASE1,TMEM45A,GPX7,CHRNB2,RIT1,OR10P1,PTPN4,SNRPB,TPM3,EFNA3,SOSTDC1,MORC2,SSR2,ELOVL1,PRDM4,FEZ1,OTX2,MAGEH1,EIF4A2,LRRC3B,FPGT,COPS5,STAT5A,HSD17B6,TMEM167B,APOBEC3F,MAP2K1,PLCB2,PEA15,RNF8,ADAMTS10,EP300,KCNJ3,COMMD6,B3GALT1,AFAP1L2,TMEM30A,GNPDA1,IMP3,IRAK4,UBL3,GNAO1,CYP21A2,NCDN,TMEM117,MRPL34,NDUFB6,SFXN2,SNX22,FASTKD5,CST11,STAT2,TAGLN3,SAV1,PCDH17,EPCAM,SRSF7,PRR3,IL22,TOR3A,GLRX,UBA3,CBLL1,TMEM179B,TOMM22,BFAR,CSGALNACT2,HENMT1,CSTF3,RPL7L1,ST6GAL1,STX11,OR2Y1,PMP22,SERPINA1,LARP4B,HSPA13,LSM10,ANKRD34B,SH2D1A,SLC11A2,PPP2R5E,UBB,LMAN1,NPSR1,MRPL11,SCLT1,LRRTM3,DAAM1,RPS7,PSMD4,NPPC,TRIM15,RELL2,GPX1,RAB27A,GRAP2,RHEB,FBXL14,OVOL1,DHX15,OCRL,MAT2B,MLC1,ZNF664,PDHB,DDX46,TSPAN18,RPS6KA4,GANAB,BBS5,XCL1,SLC6A6,CCDC134,TCF19,SLC30A7,FGFBP1,MFSD5,MRPL18,METTL21A,G3BP1,CHAC2,PSORS1C2,POP5,RPS27A,PCDHB13,TPD52,DBT,RAPGEF5,ELOVL7,DAPK3,DSTN,NUF2,OR13C8,TMEM101,HINT2,SLC16A1,CHCHD4,CHIC2,MRGPRX3,MTA2,CCDC86,SUFU,LAPTM4A,FBXL19,KCNC1,OXTR,PGGT1B,SLC38A7,TOM1L1,KDELR1,RPS16,KRAS,RBM22,RRM1,ILF2,ORC5,OXSR1,BAG3,ZNF365,PSMB1,ZMYM3,CRIP1,CNTN2,ASNSD1,DKK1,HERC4,NR2F6,CHPF2,NDUFAF3,IER2,CCS,RASD1,SHISAL2B,SCGB1D1,NLRP3,ILDR1,BMPR2,COMMD3,RND2,PPP1R1B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SPD1,OR5AP2,AK5,RAB22A,SMC4,OR8I2,GTF2E1,TNNC2,PSME1,CYP2F1,PNO1,KBTBD4,FAU,CLVS1,MED21,TWSG1,OCIAD2,PAIP1,SSRP1,PSMC1,GOLGA5,OSBP,DNTT,HPGDS,NDUFS3,OR9K2,RLN2,GIMAP4,MORN4,UNC119B,TBC1D4,TFEB,CES5A,HSCB,SYVN1,GABRB2,ARMC1,RERE,IL6,PPP1R12A,CCDC122,GRID1,TLR2,FGF10,LGR4,DYNC1I1,HECTD1,PPIG,NRBF2,PPP4C,NAA35,GSTM2,UBFD1,DNAJB2,PSMA2,GGT7,EFHD2,RSAD2,RAB30,NICN1,PFDN4,COMMD5,SST,GABRA2,CNR1,NPY,PLA2G12A,CAMLG,DAD1,MFN1,ZBTB2,TAS1R2,TYW3,SNX18,LNX2,RFC2,CNTN1,ZER1,CPNE1,GNB4,MATN4,DDAH2,ACTB,RPS13,RNF121,PGAM1,AP2S1,UGDH,EID1,MMP21,ZNF280B,NFKBIB,CHCHD3,EPO,FNDC9,PPIH,DCUN1D5,CD1A,HSP90AA1,HDDC2,SOCS3,PTPN22,PDRG1,FOLR2,OR51M1,GNG13,TUFM,IDH1,IFNA2,METTL6,RASL10A,SRC,CD2AP,KRTAP12-4,MPZ,VPS28,MKKS,SLC35B4,CISD1,MORC4,LANCL1,PIK3R3,TERT,DHRS7B,BAHD1,TRAF3IP2,TOMM20,PTGER4,PIP5K1A,PSMB6,ZCCHC17,PEG10,IZUMO1,CHRDL1,NLRP6,PSMD12,CCT7,CKLF,MS4A7,PDCD1,SLC25A11,PAFAH1B1,KCTD15,MCM3,RNF115,CDC42EP3,IFIT2,SECISBP2L,RAB33B,RGS19,ENTPD3,RASGRP3,MGAT1,RCE1,CELF6,FCGR2A,NAA50,TUBA1A,RPL7,YTHDF1,MED31,SH3BP5L,ICAM3,UNC50,NEUROG2,MTMR6,CCDC85B,SEMA6C,LUM,CHST11,HMX2,FLRT3,TNFSF13,LRIF1,TMC7,FTL,STIM1,GRPEL2,SLC39A3,SLC25A28,CXCL12,MSL2,FLCN,KLHL12,PPM1D,IDO1,SERPINI1,ZNF668,CD248,RPL35A,RSRC1,ARHGAP5,ZNF575,MRPS7,CCL20,GLT8D2,SPATA6,VTI1B,TCAP,MYOZ3,EIF4E3,ZRANB2,PCDH9,LIN7B,RIC3,DES,ARHGAP25,NSFL1C,TMEM190,OGN,SCPEP1,POMT2,NDUFB10,PADI2,POLR2F,SCN3B,NMI,OSGEP,MOG,PLSCR4,LRRC57,IFNGR1,NUP50,RIMS4,NDUFA2,TLE1,ARL6IP6,BTF3L4,HMG20A,NTPCR,YBEY,MRPL10,IL15,CYP27B1,PNOC,NIF3L1,GNG5,TMEM14B,DHPS,RRN3,UTS2,NUFIP2,HINFP,GNB3,TMEM229B,BTG2,ITGB8,CCDC3,VAV2,PAIP2B,LRP10,NR1I3,TRIM44,GPRASP2,PQBP1,PPWD1,FHL3,FAM20B,TICAM2,HSPB6,HSPA5,SERTAD2,GNA11,NRM,MPV17L2,CRYBA1,WDR45,THAP8,PARD6A,TCEA2,LRRC28,PNPLA4,PIAS1,TMEM115,NPC2,HSPD1,EIF1AX,RNASEH2C,DDR1,SLC22A6,TIA1,SPG21,CAP2,EXOC3,SAP18,TMEM81,PIGA,GLOD4,MX1,BOLL,THOC3,S100A11,ATG9A,ZNF622,RBMS2,TGFB2,SLC25A27,VPS54,GRPR,IGFBP3,GADD45A,OR1M1,CD9,RUSC2,BTG3,DPEP3,TMEM183A,CTTNBP2,RGN,FKBPL,RAB6A,CDK7,SIN3A,SCAND1,PSMD7,PLAC1,PYCR2,TNFSF8,CDIPT,PDE2A,ZNF428,TLR8,PMPCA,NOG,ARFGEF1,CRY1,TNFSF15,SLC6A2,AIP,CD40,RPA2,TMEM107,YPEL4,LDB2,GADD45G,RNASE9,TAB2,SRPK2,TRAF3IP3,PIWIL1,CCDC90B,EID2B,PRCP,CD34,FBXL4,THAP1,UNC79,CPXM1,OR4A47,TMEM100,DCTPP1,PDCL,SUPT5H,STAR,TRIP4,RPL10,GK5,SSNA1,GLCE,SLC25A24,PTGFR,IL2RB,IP6K1,CD209,ST3GAL2,TAS2R7,P2RY4,FBXW4,RAP2A,MSH6,MDFI,PPP1R11,OR4D5,TEX261,ZDHHC16,OR51E2,GP9,KRTAP8-1,POLE3,RNF10,PSMD3,DTWD2,GPR160,POLR1D,CYP4V2,APLNR,CNPY3,SRI,NCAPG2,RPL18,TKTL1,GIN1,KRIT1,VPS72,KCND3,FUBP3,ROCK2,TRAF6,CLDND1,ETNK2,CCDC106,SPRY1,RPS10,UBA52,FUNDC1,AP1M1,ECHDC1,TRAM1,TADA3,IMPA2,MTCH2,ITM2B,SP1,TRAPPC6A,MDC1,MGMT,AQP11,TLCD1,RBP2,KCTD17,CLEC6A,RASSF8,SSBP4,OR13A1,MAGEC2,PSEN1,LMO2,FKBP1B,LCORL,EDA2R,ANKRD6,FAM161A,YTHDF2,ACER3,MREG,DIRAS2,SRFBP1,PFKFB2,ARHGAP12,EIF5B,ZFAND6,MED10,TYMS,TAPT1,SCML1,GJC1,RUNX1,SLC12A2,RPS20,NAA16,VPS18,GHRL,KIF3C,CIAO1,ATP8A1,SUCLG2,DUSP3,PDE7A,SNAP25,RXRG,IGF1,CCR7,GMPS,TTC9C,GORASP2,THUMPD1,GALNT2,ANXA4,RASL12,IL18BP,GRIK1,CMA1,DLGAP4,SNRPE,RRAGB,LBX1,NKAP,GALC,ELFN2,RP9,HAUS2,OR5M9,SSPN,GNGT2,CNPY1,LRRC8A,PIH1D1,KCTD3,RDH11,MPG,TANK,BRAP,SYNGR3,MBD3,CDC23,DMPK,SLC35E4,FAM136A,MACROD1,ADCK1,CYBRD1,ZNF518B,FAM151B,OAZ1,TOPORS,LYZ,WSB1,PRR13,SLC25A5,IRF7,SLU7,MFAP3L,FAM3C,PTP4A2,SULT1B1,RPE,OR8B4,TMEM165,KLHL25,CENPL,NUCKS1,TRIM26,IER3,RAMP3,CPNE2,TMBIM1,IFT172,CYTH4,TOX4,KLRC2,SUPT3H,UPRT,FXN,MRPL9,UBE2G2,FEM1B,MRPS17,SGIP1,MECR,NBN,VMAC,TNFAIP8L1,SEC13,IL2,FHOD3,SLC35B3,WDR11,NHEJ1,TYROBP,TBC1D25,PEX13,AIPL1,SNRPG,TIMP4,ACCS,XRCC5,CDC20,ZDHHC4,WDR5B,DUSP21,TRIM45,ATAD1,MRPS34,CYP2C9,IGSF11,SGMS1,MGAT4A,RBBP8,NDST3,FBXO8,OLR1,SLC19A3,CDC7,PRL,MPPED2,KLF3,CHRAC1,CCR4,SUMO2,TFB1M,SNRPB2,LZTFL1,PPAT,IL17F,CYGB,NUDT9,GGH,TNF,BANF1,ABHD12,NF2,PARP2,FOXA3,KLHL1,CARTPT,SESTD1,CGGBP1,RPL26L1,PHF13,PRKRA,TSPAN17,WDSUB1,GNRH1,ZNF451,PRKCE,TMEM170A,RNF133,COX6B2,TAS2R13,DBR1,FSTL1,POLR2L,POLDIP3,RHOBTB3,HGS,UBE2E2,CD81,ELK3,CRISP1,LRRC40,DPH3,MT1E,TSPAN15,TMEM38B,NPM3,CRTC2,ATP1A3,PEBP4,GH1,BAX,PSD2,NUDT2,COCH,FEM1C,VTA1,RPIA,PIK3AP1,XAF1,COX6C,PICALM,LST1,ANKMY2,RBM27,ZBTB39,CPT1B,CNN3,AKR1B1,TAB1,SF3B1,ADORA3,APEX2,AP1S2,LY96,TMEM47,MAD2L1BP,NDUFS2,PAIP2,TMEM185A,JAKMIP2,PSMC3,CDH11,IVNS1ABP,PIK3CA,FAM83B,SNRNP40,BCL6,SSX2IP,DLST,GTF2F1,TMED9,E4F1,GSTCD,MTDH,USP6NL,SGTA,CA2,SNX10,TPPP3,ZNF263,TMEM89,GABRA1,HSD17B10,CAND1,PRNP,MIS12,GTPBP8,HS2ST1,CBX3,DR1,BCL9,ASPA,TRPC1,ELMO2,LYPD6,BOK,TM4SF18,OR6X1,TNR,ABHD8,ICAM2,YWHAZ,STARD3NL,CAPN2,LSM14A,SLC8A1,OR8H3,TM4SF20,CCNA2,AASDHPPT,REEP4,RNF222,SURF2,SLC29A1,MAGED2,GJA1,SPATA2,SLCO3A1,ADORA1,KCNJ10,SHPRH,TAF1D,PCGF6,GRM1,OR4K2,CXCR3,MAGEB10,HOMER3,STAMBP,SLC25A1,FAM81A,CEND1,ZNF511,EHD4,TNNI3K,CPLX3,GCLC,PSMD10,NPY1R,LIAS,TXNDC17,ARL4D,CITED1,KCNJ2,EPHA4,CTU1,FBXW7,TNFAIP6,PSMB7,DLK2,CDK12,DMTF1,PLG,TSR2,CHRM3,FRZB,SPP1,ING2,ARL2BP,ZNHIT6,PRSS23,PLCB1,GPC1,GPR17,PTP4A3,PLSCR1,DCAF12L2,LY6H,LILRA2,TNKS2,STK3,CBLN1,COMMD9,HSPB2,PROK1,JAK2,TRIM36,NT5DC1,MRPS18C,CREBZF,PAQR3,HFE,GPR35,DDAH1,NDUFA1,HCAR1,TMEM127,GSTA2,FAM53C,MCL1,PNMA3,DPH5,CORO6,OIP5,TRIM29,RB1,ZBED1,BLCAP,NINJ1,ICOS,TRIM34,NDUFC2,RGL2,ITGB5,RPS2,TCEAL8,LXN,YIPF3,B4GALT4,CAV1,PDE4B,SPEM1,CYP3A43,MEPCE,EIF3G,PMAIP1,TTPAL,UBE2L3,CCIN,FTSJ1,CNTROB,PRND,CPLX2,HUWE1,ABHD10,MRPS11,RAB39B,CSNK1G3,AKR1C1,RNF7,MRPL16,TECR,ARGLU1,EZH1,FHIT,ARL11,MAP3K3,MFAP1,MXD1,UCP2,TMEM106B,UBE2I,MED29,PNRC1,LAMTOR2,SLC41A1,SERINC1,SNRNP70,PLEKHF2,TDP1,SPCS1,MID1IP1,GLIPR2,ZNF362,MSN,FGF16,HBM,POU5F1,SAP30,RNASE4,DDIT4L,SLITRK5,IL21,RPL19,DICER1,MAGEB1,SLC6A7,UBE3A,S100B,TNIK,LRFN3,OR4B1,PDE6D,OR5K1,PDZK1IP1,CACNG3,RIT2,SMARCE1,PITHD1,LEP,SH3BP4,EFNA5,ASPM,ZC3H14,CBFB,CETN2,TADA1,ZC4H2,RPL7A,CXXC1,LSM12,FIG4,DOK5,MAP2K3,SEC22A,DCTN4,ARF6,PPT1,B3GALT2,ZDHHC24,RCHY1,SPHK2,FGR,MRPL12,EMILIN1,PRDX3,PDCD5,ZBTB26,LRRC14,BTBD10,GNG11,ARF1,EIF2B2,ZMYM6,CKB,TUBA1B,THAP6,MRPS26,PHF7,HMGB1,FA2H,ERRFI1,HNMT,ZHX1,SERTAD1,KCNIP2,LPCAT3,GPR83,DPAGT1,CTSA,PPIL3,ZCCHC7,CXCL10,ZNF345,EID2,KIAA1958,MAEA,FBLN5,FOXD3,LYRM2,DUSP18,ZNF770,TPD52L1,ASCC1,CDH7,SMUG1,SVIP,GAD2,RSBN1L,METTL18,TTR,SEC61A1,FAM83A,RHOG,NOL12,SDHC,RGS1,ASB11,BGLAP,COX7B,CDC42SE1,APOBEC3B,PCBP4,MLH3,CRYBA4,PITPNA,RAB32,FOXC2,CRYZ,BLVRA,MED27,RANBP10,SRM,ADH1B,MPP1,BARX2,PSMD1,HS3ST1,TULP3,OR4M1,BMPR1B,ATG3,INA,CFTR,OR5AN1,CLP1,CLPX,SART3,PTPRZ1,IFI16,VPS39,SUPT4H1,FAM174A,MYLIP,ART5,TMEM39A,CDK17,PSMB10,VWF,ESD,GPR37,CDKN2D,ATP6V1D,TTLL10,TP53TG5,DIRAS3,HDAC11,SIGLEC5,ATG16L1,LCP1,AGGF1,HNRNPH3,IZUMO2,ZNF200,TPST1,SKP1,CHCHD2,GCHFR,GJB1,KRT8,PRELP,CSF2,PCYT1B,HCFC2,PABPC5,PRKCB,IRF2BPL,LSM5,DCTN3,COPE,RBM41,RWDD1,SLC25A3,HBP1,DYNLRB2,CKS1B,SUV39H1,RGL1,SEC14L5,RPL4,CDC26,SHC3,PREP,CYP4F22,ARFGAP1,PIGC,STK38L,MVD,EDEM2,CACNB2,HCFC1R1,RPL28,SRP72,DDIT3,SLITRK1,VCPIP1,OAZ3,PGAP3,MB21D2,LCN15,MCCD1,SLC39A10,HM13,BCAS4,TCEA1,LIPA,PTPN5,UFSP1,RELL1,TIMM17A,SMAD9,RNF182,ALCAM,JUNB,SNRPD1,CCL24,SLA2,SDR16C5,IFNAR1,MARCKSL1,RAB9A,RXFP2,RPAP3,CCL11,TNPO2,THOC6,PYCR1,HINT1,DYNLL1,SMG5,RNF139,NUP62,ABCF1,DUS4L,PLP2,OPRL1,HSDL2,LYPLAL1,IRF4,CSRP1,LEMD3,STX5,RAB11B,ARL6,CCND3,FMOD,ADRB3,CMTM7,SPATA4,CA12,SLC7A1,TBC1D16,STT3A,MAGEA4,RACGAP1,CORO1C,RRP7A,CCDC126,RBM3,ERLIN2,UBE2S,HYAL2,RHOH,ARHGAP15,RPSA,PIK3CG,NPBWR1,FOSL2,GNPAT,ACP2,ACTL6A,GPR75,SETD3,TMEM126A,CHTOP,SYPL1,WBP11,ZNF436,EGR1,DIO2,STARD7,ZNF343,PDLIM4,THG1L,ERCC3,GABBR1,GPR34,TBC1D1,TIMM13,XBP1,RPF2,EMILIN3,DRD3,NAP1L3,CEACAM5,NACC2,CHRM5,OSBPL8,CEP57L1,ARHGAP19,TACR1,DIS3L,CA14,MED4,ZCRB1,CYB5B,OR9I1,TRMT5,BCKDK,SEMA7A,NAP1L5,LIPT2,HPCAL1,MRGPRX1,ECD,CD59,AQP3,ETFA,PRELID1,GPM6A,COTL1,PNPO,OR2D3,RFC4,LCN1,TLR5,TICAM1,HS3ST3A1,AKT2,GAB1,ITPRIPL2,PSMC5,APEX1,PRSS1,SOX9,CHST10,KCNG3,REG1A,PLCXD3,C1QL2,OR4K13,GTF3C4,MMP20,DCAF16,SRD5A3,CLRN2,SUGP1,ABCC2,STARD5,FMO1,DEXI,ALG5,HTR2A,SMARCB1,STAP1,ACTR1B,ANKRD10,TEF,SCN2B,SOD2,ADD2,PCP2,TCTA,WDR12,MLN,KLF12,CNOT8,PELI1,PIGK,FBXO31,VSTM2L,MAP1B,PDCD1LG2,GLO1,RAB1A,VSTM4,AMELX,NEU1,NCK1,SIAH1,LRP3,STRADB,CD200,TMEM220,ST8SIA4,USE1,TMEM168,GPR78,TEX19,ZNF655,TRIM62,KCTD16,SLC15A1,PLEKHF1,ZBTB6,AHSA1,HMGN4,SCHIP1,TAF9,MEA1,CDKN1B,COX7B2,CMBL,TRAPPC2L,TMEM198,RFX5,NMRAL1,MAT2A,OR6C4,PHOSPHO2,RPL31,WTAP,LRRN4CL,GDAP1L1,SSBP2,PDCD10,CRHR1,AKR1E2,UQCRC1,NOC4L,BAD,TSPAN3,MGST3,PRPS1,HAS3,OLA1,ZMAT3,BRS3,SKAP2,CLK1,KCTD20,RASSF4,SERPINA3,TRAF1,RSL24D1,IRF9,HSD17B8,LSM4,CGRRF1,DDX39B,HERC3,PSMB4,DOK6,SEMA3C,C9orf72,NAA30,NETO1,PTGER2,CDR2,AANAT,SAP30BP,HAPLN2,EDC3,F2,ARL5B,ESYT1,CAMKV,YKT6,VPS26B,ANKH,MFSD3,BIRC5,GMDS,WNT2,LDB1,CSRNP3,NRGN,TRAPPC3,KDM1A,NDFIP1,CCDC22,CTDSPL2,ANKRD46,CEP70,ARL6IP5,ABHD2,SNRPA1,SNN,PSMG2,TMEM87A,ISG20,NUDT1,RALB,CYP26A1,GMNN,TBCEL,PRSS35,FKBP2,UNC45A,PDE6A,HELT,IMP4,RPLP1,SNX11,TIMMDC1,UBE2V1,MT1X,SERPINB9,PRM1,GAL3ST4,ADIPOR1,SLC7A11,RETSAT,POPDC3,FZD6,MET,HOXB8,SSH3,CENPM,SEC61G,EMX2,GFM1,PDLIM3,PRSS37,MAP1LC3B,ACSS2,DEFB1,IFRD1,RANBP1,ATF3,RBM5,CTLA4,RPL22,CEBPE,TMEM176B,RHOU,DLG3 |
| 1.020e-19 | -43.73 | SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70) | protein interactions | 6625 | 961 | 397 | 19454 | 5460 |
THOC2,FOLR1,PHB1,MYEF2,RPLP1,HP1BP3,GATD3,NOP58,SPTAN1,CCAR2,RPL7,PRPF19,MRPS35,WDR11,TRA2A,DDX23,RSBN1L,RPL23,ARGLU1,PPAN,RPS24,SRSF8,G3BP1,SRSF4,MRPS17,RFC3,RFC2,E2F4,EZH2,SF3B5,GTPBP1,CPSF1,ZNF22,FAU,RPL37A,RPL7L1,RPL35,RPL19,SNRPB2,CUL3,CFAP20,CUL2,RFC5,RBM15B,MYO6,NOA1,RIT1,THOC3,UPF3B,G3BP2,SKP1,TIMM13,APOBEC3C,MYL6,AIFM1,SRP14,TOP1,DBT,ZBTB2,APOBEC3F,TIAM1,MPHOSPH10,ZNF787,ZC3H11A,CTNNBL1,PAK1IP1,LSM4,THRAP3,OLA1,RPS13,MRPL22,SNRPG,MSH6,YTHDF2,MRPL11,SMAD1,RPL15,GEMIN7,ILF2,MRPL49,MRPL51,OPTN,EIF4A3,PRKRA,RPS20,CFAP298,MAGOHB,RPL13A,TECR,SMAD5,RPL22,RUNX1,DEPDC1B,PPP1CC,NONO,CASC3,PRPF4,SIRT7,MTDH,DGCR8,EIF5B,RPL4,CPSF4,RPS14,SAP30BP,SNRPN,MRPS34,CDK1,LSM2,RPLP0,POLR2L,SRSF1,MAGED2,EED,EIF2S1,PAIP1,FAM98A,LYAR,MRPL9,DIS3L,SMAD9,DRG1,CMTR2,PABPC1,RBM3,TOP2B,RTCB,RPL28,HNRNPDL,TNPO2,KIF2A,CAAP1,MTA2,ZRANB2,RPL18,SF3B4,SNRNP40,DES,RBM27,FTSJ3,H1-10,CHTOP,THOC6,GTPBP2,DNAJB6,PYM1,SNRPA,RFC4,EP300,HNRNPA0,STAU1,SAP18,MRPS7,RPL27A,MRPS18A,SYNCRIP,RPS16,NKAP,DKC1,RBM42,CDC5L,CMSS1,RBM17,COPS5,TMA16,CSNK2A1,MZT2B,SMAD4,SNRNP70,CDK12,RPS2,RPL10A,USP15,SNIP1,MRPS18B,RPL3,TOLLIP,KPNA2,SRSF12,UBL4A,MRPL47,IK,RBM34,RPS3,MRPS28,EIF2S2,MRPS21,BUB3,CSTF3,SMURF1,SRPK2,RSPH1,RPF2,RPS17,RC3H2,ELAVL2,CALU,EXOSC4,HNRNPH2,RNF113A,MRPL41,MRPL40,ZC3H15,HSPA5,MRPL10,GTF3C4,ZNF326,HEXIM1,RPL8,RPL9,MRTO4,IFIT2,KRT8,RPLP2,SRSF10,DHX15,HNRNPA1,MRPL18,WDR12,HNRNPD,VPS4A,MRPS26,MPHOSPH6,HNRNPA2B1,MRPS11,SRSF7,GTF3C3,SSRP1,AHCYL1,RAF1,RPL29,SKA3,CHMP4C,RPS11,SNRPE,RSRC1,SNRPD2,SNRPD1,RPS9,MRPL23,PRRC2A,ERH,MRPL16,PRPF31,RPS29,FYTTD1,ZCRB1,RPS5,LSM14B,CYFIP2,YTHDF1,RNF11,USP39,LARP4B,SMAD3,RPL12,KRR1,RPL35A,DCUN1D1,MRPL50,CDK9,NCBP2,CWC15,MRPS23,MRPL24,MOV10,GRSF1,FOXP1,PPP1R12A,NKRF,RPL23A,NOC4L,MRPS18C,SMN1,CD2BP2,CCNF,MRPL53,EIF2AK2,TUBA1B,HEXIM2,RPS12,TMOD3,VIRMA,DEK,RPL26,SMAD2,PPIG,KIN,PPIH,MRPL17,FBXW7,BRIX1,MRPL20,SF3A1,TXNL4A,PIP5K1A,METTL14,RPL26L1,HNRNPH3,WTAP,FUBP3,WDR82,RPS10,HNRNPL,SNRPA1,SNRPD3,SUMO3,IFI16,DDX50,WWP2,RPL6,XPO1,DDRGK1,DDX1,MAGOH,RPL31,ABCF1,EWSR1,HNRNPF,KGD4,RUVBL1,RPS4X,CCAR1,PRPS1,TRMT1L,RPS7,PTRH2,RPS23,PRMT5,SMU1,MRPL13,MATR3,RPL10,ESR2,MYC,APOBEC3B,HNRNPAB,HNRNPC,BTF3,DRAP1,SNRPB,CPSF2,CIRBP,MRPS25,RPS26,DDX39B,RPS28,DDX5,UFL1,SRSF2,FXR2,TRA2B,ZC3H14,MRPS9,PDE9A,RPL32,ALYREF,CAND1,FZR1,RPS27L,MYL12A,TPM3,RPL24,AKAP8L,MAP1B,CLPB,DHX9,H3C1,MRPS33,HNRNPK,MEPCE,RPL17,STRBP,RPSA,TP53,CDK8,MRPL33,NUPR1,PHAX,CSNK2B,DYRK1A,SMARCA5,RPL7A,MRPS16,GEMIN8,EXOSC1,IGF2BP1,OAT,UBE2H,RPL27,LSM12,RPS15,NME4,CDC42,TFB1M,TFIP11,LUC7L3 |
| 1.082e-19 | -43.67 | NPM1 (nucleophosmin 1) | protein interactions | 4869 | 1118 | 450 | 19454 | 5460 |
SP1,ELMO2,LMNB1,ZNF668,RFC5,CUL3,NOP16,CUL2,CHCHD3,RPL19,RPL7L1,RBBP4,RPL35,RPL37A,ARF1,CPSF1,ZNF22,FAU,EIF3K,H1-5,G3BP2,GPC1,HAND2,CRY1,NMRAL1,NUP50,CCDC86,RSBN1L,RPL23,DDX23,TRAF6,CACYBP,CGGBP1,RPL7,RPLP1,HP1BP3,COPS2,THOC2,FOLR1,PHB1,EIF1AX,PLD3,EZH2,MAK16,ASPM,LGR4,MRPS17,RFC3,RFC2,G3BP1,LAMB2,KCTD17,TRIM37,JAK1,RPS24,COX8A,TRIP4,CASC3,ATP5F1A,PPP1CC,TUFM,NONO,CSK,RPL22,ZNF622,TXN,RPL13A,PRKRA,SENP5,RPS20,TRIM24,CHCHD6,PELP1,RPLP0,MACROH2A2,LMNA,JUP,MRPS34,CDK1,CPSF4,PSMC4,RPS14,AATF,NPM3,HMGB1,RPL4,MTDH,SQSTM1,SIRT7,PNO1,MPHOSPH10,HDAC6,MPG,CALR,TLE1,TOP1,RCHY1,MRPL49,SRP72,EEF1A1,RPL15,MRPL11,FBXO25,RPS13,PRDX4,EIF3E,CTNNBL1,PAK1IP1,PC,ICAM1,NSA2,FTSJ3,H1-10,PSMD4,CAVIN2,SNRNP40,PIH1D1,RPL27A,NUP62,RPP14,HNRNPA0,EIF1B,STAU1,HSPA8,HDAC5,EP300,RFC4,XRCC5,HSPB1,R3HDM4,AGR2,CENPW,RIOX2,UQCRH,EIF2S1,FAM98A,TCP1,DYNC1I2,LYAR,MAGED2,SRSF1,RPL18,SOX2,MAX,RPL28,LECT2,KRAS,VDAC1,HMGN4,DNAJB4,RTCB,PABPC1,TOP2B,CALU,EIF3G,RC3H2,TRIM23,DNAJC10,RPS17,RPF2,SRPK2,BCCIP,RPL10L,EIF2S2,PSMC5,RPS3,ZNF330,HEXIM1,UBE2M,PRKCA,UTP15,ZNF770,ACACA,RPA2,SAMM50,MRPL10,GTF3C4,NEK2,CFTR,ZC3H15,MARS1,HSPA5,MRPL41,RNF113A,PRDX6,RPS2,USP15,RPL10A,SNRNP70,COPS5,CSNK2A1,CMSS1,DKC1,RBM42,SLAIN2,SURF6,IFRD2,RPS16,TRMT10B,CD4,ARL4D,EEF1B2,AIP,TAB2,RNF8,DNAJC2,RBM34,H2AX,IKZF5,UBL4A,MRPL47,H2BC14,IMP4,MRPS18B,RPL3,SNIP1,HSP90AA1,RPS5,FYTTD1,DCAF4,BRCA1,YWHAZ,IRF1,RPS29,MTG2,NFYA,PRRC2A,EIF4A2,RANBP6,RPF1,TENT5C,ACTB,TAB1,SIAH1,SNRPD2,SNRPD1,RPS9,SEC61B,SLC25A3,ARMCX3,H2AC1,EMC9,LARP4B,ATAT1,DET1,CDKN1A,PYGB,STX7,CMAS,NOP53,PSMA3,EMG1,HNRNPD,MRPS26,DICER1,MRPL18,CDK5RAP3,WDR12,HNRNPA1,HMGA1,PIK3R1,PPIA,DHX15,RPLP2,RPL8,RPL9,RPS11,CHMP4C,EXOSC3,PPID,PPP2R1A,RPL29,RAF1,BUD23,B3GNT2,PSMD12,SSRP1,TNF,S100A10,BAG2,ZYX,SLC25A5,HNRNPA2B1,GADD45A,DNAJC19,UBB,JUNB,VIRMA,GNAI2,COPE,RPP25L,MSN,RPS12,CCNF,MRPL53,EIF2AK2,ENO1,POP7,CTTN,RPL26L1,METTL14,CDK7,NFYB,TMUB1,BRIX1,MRPL20,FBXW7,CLK1,PPM1G,RPA3,GID8,BRD3,MOV10,SPATS2L,MDM2,CDK9,MRPL24,MRPS23,DCUN1D1,MRPL50,RB1,KRR1,TAF1D,MAP2K3,EXOSC8,FBP1,SMN1,HUWE1,VRK1,RPL23A,RAB1A,FAF1,PPP1R12A,NKRF,RPS26,RCL1,H1-1,CCT2,PNRC1,MRPS25,H2AZ2,S100A11,BTF3,PSMD1,CPSF2,MYC,HNRNPC,RPL10,ESR2,APEX1,NCKAP1,ZCCHC7,CMTR1,NUFIP2,TRMT112,MRPL12,MTF1,UFL1,FXR2,ZNF692,EEF1G,NGRN,RPS28,DDX1,ARHGAP5,XPO1,CTNNB1,NGDN,DDRGK1,LAMP2,PROS1,BAZ1B,DDX50,WWP2,RPL6,PEG10,TRMT61A,HSP90AB1,NOB1,ISG20L2,RPS10,OSBP,SUMO2,SWAP70,RPS23,DNAJC25,H1-3,EEF2,RPS7,TRMT1L,RPS4X,EWSR1,TRIM21,RPL31,ALKBH4,PDCD4,UBE2H,CHCHD4,CFL1,AKT1,SMARCA5,RPL7A,RPP25,RSL24D1,DYRK1A,TXNDC12,CSNK2B,SEC61A1,RBMX2,SRP54,MACROH2A1,DYRK2,WWP1,WDR55,RPS15,WDR3,STK38,RPL27,BAP1,PML,NLE1,NOL12,KPNA1,RPL24,SHC1,PPIL4,CD81,API5,GAPDH,ENY2,MBD5,CAND1,FZR1,RPS27L,DSTN,MRPS9,RPL32,NUPR1,CBX3,SURF4,DISC1,IMP3,TP53,RPSA,MEPCE,RPL17,H3C1,SCML1,MRPL52,MAP1B |
| 1.186e-19 | -43.58 | UBE2O (ubiquitin conjugating enzyme E2 O) | protein interactions | 63893 | 776 | 333 | 19454 | 5460 |
EIF2S1,NOB1,FAM98A,TRIR,PEG10,CORO1C,MAGED2,DDX1,DRG1,RPL6,PTDSS1,TOR4A,PTPN4,PSMA1,RUVBL1,HNRNPDL,RWDD4,RPL31,ABCF1,MYO1B,RUVBL2,FBXO11,PDIA6,RTCB,SREK1IP1,TRIM11,PLS3,TUBB4B,SMNDC1,H2BC1,RPS23,RPL18,PPIL3,TRAF2,REEP3,CAVIN2,PSMD6,PSMB6,RPL10,LMBR1L,GTF2F1,GTF2F2,COX16,FTSJ3,H2AZ2,CHTOP,RPS26,DNAJB6,NSA2,MYC,LDHB,PSMA4,OSM,ISCA2,BRMS1,UBE2D3,EEF1G,STAU1,SAP18,SLU7,LCA5,RPS28,MRPL34,HSPA8,ARRDC3,LCN1,GRIK1,CSNK1A1,TRMT112,TOMM22,RPL27A,IFRD2,CPNE1,FZR1,NKAP,CXCL9,RPS27L,TMPO,MXI1,SSBP1,MRPS9,COX4I1,SNRNP70,CHCHD1,RPL24,ZDHHC15,NOL12,RPS2,RPL10A,CMSS1,RBM17,ZNF24,TMA16,CSNK2A1,E4F1,ELOC,PSMA5,CSE1L,KPNA2,TMEM33,MEPCE,RPL17,NOSIP,TCEA2,SLC16A1,DDX42,CBX3,SURF4,CAPZA2,GNAI3,ATP5PB,RPSA,TP53,CCL20,YIPF4,ESS2,H2AX,IKZF5,BUB3,CDC20,TRAF1,SF3B6,PSPC1,ZNF330,TMA7,CSNK2B,EIF2S2,PSMC5,SPOP,EIF3G,ELAVL2,UBE2H,ALKBH5,RRP7A,MAT2A,PSMB2,RPL7A,SUB1,RPS17,CFL1,RPS15,TOMM20,BAP1,RPL27,NBN,PRDX6,RPA2,HEXIM1,GSTP1,ZNF770,CYC1,AGO1,FGF13,NOP58,RBIS,DHX15,RPL8,THOC2,PSMB5,RPLP1,RPLP2,CSTA,TRAF6,HNRNPD,MED4,BCL2L1,RPL23,HMGA1,PRPF19,INO80E,ZNF207,RBBP7,DHX16,ETFA,RPS27A,MCM6,RFC3,SSRP1,RAD21,RFC2,AKT2,HNRNPA2B1,ARGLU1,PRPSAP1,FAM76B,ERP29,RPS24,MRPS11,EZH2,RPN1,RAB6B,PRKAG1,RPS11,GTPBP1,SNRPE,BUD23,FEN1,MAK16,PRDX2,MRPL23,MED17,RPL35,SPINDOC,TAB1,RPL19,GNB1,ERH,GNG12,PELO,EIF3K,RAN,RPL37A,SEC61B,ZMAT2,FYTTD1,DCAF4,MYO6,PYCR1,NOP16,PRPF31,RPS29,HSCB,POLA2,RNF11,EEIG2,THOC3,MCRIP2,ATP5MK,HADHA,RNF10,PSMA3,APOBEC3C,PCLAF,SLC25A3,WDR77,PRKAB1,PPP1CB,KLF1,TOP1,PRNP,THOC1,MRPL50,MDM2,ATP5PD,AKAP17A,PTP4A3,CAV1,MRPS23,ZBTB2,NOP9,AIFM1,NAP1L5,SRP14,HACD3,KRR1,PSMB1,SLC2A1,MOV10,MPG,LSM4,FARSA,THRAP3,SMN1,RIGI,PPP1R12A,NKRF,MRFAP1,RPL23A,CPNE2,HAPSTR1,ACTR2,ILF2,ZFAND2A,JPH4,AURKAIP1,LBR,RPL15,FNTB,NDN,MGST3,TMOD3,NR1H2,UBE2L3,SFRP4,VIRMA,CCNF,EIF4A3,TUBA1B,POP7,RTRAF,GSK3A,TRIM27,SYT2,ODR4,ALB,RPS20,IVNS1ABP,PIP4K2C,TXNIP,STK11,CASC3,PPIG,ZNF687,PPP1CC,DNAJC8,KPNA6,DGCR8,NHP2,PPM1G,RPA3,ZKSCAN1,SIRT7,CCDC106,TCEA1,ARPC2,JUP,LMNA,HSP90B1,ZCCHC17,EPHX1,RPL26L1,RPLP0,ZNF574,WTAP,WDR83,PSMC4,SAP30BP,RBFOX2,RPS14,UBA52,TPT1,PIP5K1A,SNRPN |
| 1.303e-19 | -43.48 | RPS15A (ribosomal protein S15a) | protein interactions | 6210 | 382 | 190 | 19454 | 5460 |
RPL35,TUBB,RPL19,FAU,RPS9,SEC61B,RPL37A,BRCA1,RIT1,HSP90AA1,RPS5,CUL3,CUL2,RAB11A,ACO2,AUH,RPS29,MRPL16,UCHL3,G3BP2,COIL,PSMC1,EMC9,ELF5,RPL7,NOP58,PHB1,RPL8,FOLR1,RPL9,RPLP1,RPLP2,BCL2L1,RPL23,AHSA1,PSMD3,HNRNPA1,GNL1,G3BP1,RAD21,UBE2A,RPS27A,SLC25A5,RPS24,UBE3A,CHMP4C,EZH2,RPS11,B3GNT2,RPL29,RPL13A,NDN,COPE,VIRMA,RPL22,SH3BGRL,METAP2,CCNF,RPS20,PTEN,RPS12,GSK3A,TUFM,PPP1CC,ATP5F1A,FBXO7,FBXW7,RPL4,HMGB1,PNO1,RPA3,RHOU,H2AC7,METTL14,RPLP0,UBA52,RPS14,CDK7,PRNP,RPL35A,CDK9,RCHY1,ACTA2,RPL12,SRP14,PSMB1,MPHOSPH10,MOV10,HDAC6,VRK1,HUWE1,RIGI,GALNT2,RPS13,MRPL22,RPL23A,HAPSTR1,SRP72,ILF2,FBP1,RPL15,EEF1A1,RPL10,ATG3,PSMD14,LAMTOR1,RPS26,COP1,SFN,MYC,BTF3,PSMD1,STAU1,UFL1,HNRNPA0,MRPS7,RPS28,DDX39B,PYM1,HSPA8,ADSS2,CSNK1A1,PIH1D1,EIF4B,FBXO42,RPL27A,RPS10,AGR2,DRG1,MGMT,RPL6,WWP2,CTNNB1,DDRGK1,KRAS,RPS4X,RPL28,RPL31,EWSR1,RAB4A,TUBB4B,RPS23,RPL18,EEF2,RPS7,SOX2,RPL10L,SMURF1,PSPC1,RPS3,RC3H2,SPOP,UBE2H,IGF2BP1,EXOSC1,RPL7A,RPS17,RPS15,HSPA5,BAP1,RPL27,RNF113A,RPA2,HEXIM1,RPS27L,RPS16,CAND1,FZR1,RBM42,TMPO,RPL32,RPL24,SNRNP70,TUBG1,RPL10A,RPS2,ENY2,API5,COPS5,NEDD8,RPL17,MEPCE,MAP1B,RPL3,DISC1,DNAJC2,TFCP2,RPSA,UBL4A,IMP3 |
| 1.488e-19 | -43.35 | HSPA5 (heat shock protein family A (Hsp70) member 5) | protein interactions | 3309 | 1455 | 561 | 19454 | 5460 |
FAF2,PPP2R1A,RPL29,ACTN4,ERLIN2,B3GALT4,RAF1,B3GNT2,RPS11,SNRPE,RPN1,NME1,PRPSAP1,BAG2,HSPD1,SLC25A5,HNRNPA2B1,PRELP,PSMD12,COPS4,SSRP1,AHCYL1,TNF,HNRNPA1,SIAH2,PDIA3,HAX1,HNRNPD,MAP1LC3A,KRT8,RPLP2,RPL8,PPIA,DHX15,DNAJB9,LCN12,CDKN1A,NOTCH2,ELOVL1,FKBP10,SLC25A3,PSMA3,DNAJC3,WNT2,PRPF31,PNOC,ACO2,RAB11A,HSP90AA1,BRCA1,YWHAZ,SNRPD2,SNRPD1,RPS9,SEC61B,GRIA1,FCHSD2,ERH,B4GAT1,PRDX2,TUBB,B4GALT4,BMP1,TAB1,ACTB,SPCS1,MAP2K3,TOR3A,FBP1,C1QC,SERPINA1,GPX7,ADAMTS1,ACTR2,EGFL8,IGF1R,RAB1A,LTA,FAF1,PSEN1,ERLEC1,HUWE1,B4GALT7,ATP1B1,MOV10,CNN3,ADAM21,LDLR,CHID1,RPL12,EFNA3,EIF4E2,CDK9,RPL35A,DCUN1D1,CDK7,UBA52,XCL1,MET,HNRNPH3,RPL26L1,RARS1,HAUS2,WTAP,MMP28,PICALM,METTL14,SPCS2,RTN4,SOD1,INPPL1,RPA3,HELLS,DVL2,GLIPR1,WNT7A,PIAS1,PDHB,FBXO7,DNAJC8,CDC73,DNAJC19,MAPRE1,SDF2L1,ZSWIM7,DNASE1L1,ZBTB18,MSN,POLR3H,RPS12,CTNNA1,CTTN,VIRMA,GNAI2,NDN,TMOD3,TUBA1A,RPS7,PI15,DHX38,RPS23,TUBB4B,PLS3,MYO1B,SCPEP1,EWSR1,TRIM21,RPL31,MATN4,RPS4X,PRPS1,TFG,HNRNPF,PSMA2,RUVBL1,XPO1,CTNNB1,DDRGK1,DCAF4L2,IFI16,WWP2,RPL6,CBL,NCK1,SIN3A,DUSP6,HSP90AB1,COCH,RPS10,HNRNPL,RAB1B,SUMO2,SNRPD3,SNRPA1,SEC62,GPC4,EDEM3,EFHD1,EIF4B,PPT1,DDX5,DDX39B,BMPR1A,RPS28,SPECC1L,TMEM106B,PACSIN3,UFL1,EEF1G,PHB2,ADRB2,BTF3,PSMD1,BAG3,SNRPB,MYC,ST3GAL2,HNRNPAB,SFN,SERPINH1,PSMD14,PRMT5,MCPH1,DLST,RPL10,NCKAP1,TAGLN2,MATR3,PLA2G12A,ATP5PB,RPSA,TP53,INSIG2,SLC25A24,GNAI3,SURF4,CBX3,SERPINB11,DHX9,METTL18,MAP1B,PSME1,MEPCE,RPL17,NEDD8,CSE1L,TOR2A,HNRNPK,TPM3,DPP4,COX5A,MAP4,BGLAP,RPL24,SHC1,BRINP2,SSBP1,LMAN1,KLK3,MYL12A,CAND1,TMED9,MARCHF4,FZR1,DYRK2,SSR1,RNF146,SEPTIN6,RPL27,BAP1,PML,TMEM263,METTL22,CLU,RPS15,CFL1,CEP70,GORASP2,SPMIP8,AKT1,SMARCA5,NPTX1,RPL7A,ETFBKMT,UBE2H,CDKN2AIP,ATP1B3,TLR9,CHRAC1,CMA1,SEC61A1,CDC20,TXNDC12,IFI6,SAP30,LGR4,TXNRD1,GNB1L,EZH2,NGB,UBE3A,ERP29,SEMA6C,AP1M1,MYORG,RBBP7,LAMB2,G3BP1,TRIM37,EIF3D,WDR11,PRDX1,PRPF19,PSMD3,STOML2,AHSA1,RPL23,DDX23,XPO5,RPLP1,COPS2,CYB5A,FOLR1,WDR6,PHB1,PLAC9,OS9,G0S2,COPS7B,RPL7,SPTAN1,TIMM13,PRDX3,WDR77,ALKBH3,KCND3,MYL6,PPARG,ATP5PO,CRY1,NPB,HADHA,FBXL4,PSMC1,WASF3,GLT8D2,RNF40,GGH,HNF1B,CUL3,GRB10,CUL2,NTRK3,KLK5,SP1,RIT1,ATP1A3,TAFAZZIN,MCM8,FAS,MYO6,RMDN3,FAU,WNT10B,CYB5R3,PIGK,RAN,UBE2S,CHCHD3,GNB1,RPL35,DYNLL1,RBBP4,EEF1A1,RPL15,UBR7,ILF2,SEPTIN7,RING1,SNAP23,EMC2,FBXO25,RPS13,VWF,PRDX4,LSM4,ADIPOQ,HDAC6,CALR,DNAJC7,TOPBP1,CTDSPL2,EEF1AKMT3,ATP5PD,PPP1R18,KCTD15,PRNP,BRINP1,FUT8,LEP,P3H1,JUP,ZMYM6,HSP90B1,GRM2,GHITM,SYVN1,CST11,DPEP3,EGFL7,SQSTM1,PRPF4,TPST1,DGCR8,RPL4,HMGB1,ATP5F1A,RUNX1,PPP1CC,AR,CSK,NCKIPSD,NAPA,IVNS1ABP,GANAB,GSK3A,RPS20,UBASH3B,STUB1,SH3BP4,SEC63,RAB14,TXN,TOP3B,RANBP1,RPL18,METTL21A,RUVBL2,DNAJB4,GALC,PDIA6,CCT8,PABPC1,RPL28,HNRNPDL,PAEP,KRAS,GJB1,VDAC1,PPIB,LCN6,STK4,GSTM3,DIRAS2,CLEC18A,TNFSF13,HSPB1,YWHAB,AGR2,CASP12,CORO1C,MAGED2,EED,SERPINC1,ELK1,TOR1B,DYNC1I2,TSHR,NUP62,PIH1D1,PAK2,HSPA8,HDAC5,STK26,YAF2,EP300,AKAP1,DDIT3,EMC1,STAU1,COPS7A,OSGEP,ICAM1,DNAJB6,PRSS1,RBBP8,SPCS3,PLCL1,TRIM44,EFHD2,ATP5F1B,PLXNC1,TRIM29,PSMD6,H2AX,UBL4A,MTCH2,LY6H,RAP1A,SELENOF,RNF8,TFRC,TFCP2,SFTPC,DNAJC2,ARPC3,SLC16A1,RPL3,ERO1A,TRAFD1,PALM2AKAP2,ATP5PF,SLC25A11,ZBTB25,CHST2,H2BC14,CAPZA1,REXO2,COPS5,CSNK2A1,SCGB1D1,KARS1,FAM20C,XAF1,EDEM1,RPS2,RPL10A,SMAD4,TUBG1,FAM187B,SNRNP70,BECN1,EEF2KMT,STT3A,EEF1B2,COX4I1,TMPO,FIBIN,SLAIN2,CDC5L,DNAJC1,RPS16,GABRA1,NEK2,CFTR,RETN,SPTBN1,HEXIM1,UBE2M,MRC1,ANGPTL2,RPA2,SLC22A8,LDHAL6B,HNRNPH2,GNRH1,GHRL,RNF113A,ACP5,AIF1,MARS1,HSPA5,ANO3,UTS2,SLC6A6,PTPN11,SUB1,ATP1A1,CALU,SPOP,RC3H2,DNAJC10,PSMC5,INHA,CD1E,RPS3,LIG3,SMURF1,SRC,KCTD9,ADRM1 |
| 1.509e-19 | -43.34 | SOD1 (superoxide dismutase 1) | protein interactions | 6647 | 414 | 202 | 19454 | 5460 |
GLO1,HDAC6,CALR,NME2,UBE2V1,PGM1,PPIF,SOD2,ILF2,GNPDA2,HINT1,PRDX4,EIF3E,CTNND1,HSPE1,HUWE1,RGN,FKBP1B,SMAD2,LGALS8,ASCC1,ALB,TRIM24,ACAT1,GANAB,RTRAF,ENO1,EIF4A3,OPTN,STUB1,UBE2L3,LDHA,TXN,SPR,HSP90B1,LMNA,GPX4,MAVS,IDH3A,SOD1,RPA3,CRYZ,HMGB1,PMP2,EIF3D,MARCHF5,CRIP1,PRDX1,PDIA3,PPP3CA,PPM1B,ATP6V1A,CBFB,PPIA,CCAR2,CCS,ACTN4,PPP2R1A,RAF1,TPD52,ANP32A,MARCKSL1,FEN1,POLR2C,EIF1AX,NME1,EZH2,UBE3A,HINT2,SCYL2,TRIP4,ANP32B,AHCYL1,MCM6,UFM1,MCM4,MCM3,ACO2,RIT1,PFDN2,LMNB1,DCAF4,YWHAZ,ENO2,GNB1,CLIC4,TAB1,ACTB,LGALS3,PRDX2,AKR1C2,RPE,STXBP1,TIMM13,FABP7,FKBP1A,ARCN1,HEXB,CRYAB,TXNL1,ATP5IF1,PSMC1,SRI,API5,TPM3,GAPDH,PGAM1,KARS1,H2AC4,CDK6,AKR1B1,DSTN,UBE2N,EEF1B2,MIF,RAP1A,PHKA1,CFL2,MTPN,CFL1,GSTK1,MAT2A,UBE2H,SORD,ATP1A1,OAT,GLOD4,PITPNB,PSMC5,PSMA6,SUCLG2,ADRM1,CDC42,NDUFAB1,SPTBN1,GSTP1,UBE2M,RPRD1B,LDHAL6B,PRDX6,RAB9A,PGK1,BANF1,BAP1,HSPA5,DDRGK1,PPIB,YWHAG,YWHAB,GSTO1,AK2,PRCC,PSME2,FABP5,HSP90AB1,CCT7,GLRX,SUMO2,AASDHPPT,EIF2S1,EEF2,ETFB,PPIL3,RND3,PLS3,PIR,PDIA6,RUVBL2,EWSR1,CCT8,PAX6,RUVBL1,CHCHD2,PSMA2,KRAS,CUTA,HNRNPAB,LDHB,SERPINH1,PSMD14,S100A11,H1-10,CKB,CCT2,ADK,PHF21A,ESR2,DES,PSMB6,HECW1,PSMD4,TAGLN2,MRPL12,AKR1A1,KLC2,HSPA8,COX17,XRCC5,DDX39B,PEBP1,EEF1G,OXCT1 |
| 1.569e-19 | -43.30 | B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) | protein interactions | 10678 | 541 | 249 | 19454 | 5460 |
SLC39A9,PPM1G,SQSTM1,ARPC2,MTDH,EIF5B,RPL4,RPS14,PSMC4,UBA52,TMEM106A,EIF3J,CNP,JUP,LMNA,HSP90B1,TM9SF1,RARS1,RPLP0,TUBA1B,CIB2,ENO1,DNASE1L1,GANAB,CHCHD6,RPS12,PTEN,MSN,RPS20,TXN,LDHA,ARMC6,SLC25A4,RPL13A,TECR,RPL22,EMILIN1,CTSD,RPL26,TUFM,SDF2L1,XPOT,CASC3,SLC25A10,RAB1A,RPL23A,PC,IGF1R,HUWE1,ERLEC1,RPS13,ARF4,GALNT2,SMN1,TOR3A,YTHDF2,EEF1A1,GGCT,RPL15,ITGB8,SRP14,RPL12,AIFM1,ACTA2,LDLR,RPL35A,POLE3,CALR,MOV10,C1GALT1C1,DNAJC3,HADHA,PSMA3,PSMC1,CSRP1,CDSN,H1-5,TOR1AIP2,FKBP10,FAM3C,SLC25A3,FAU,CD79B,ARF1,RPL37A,RPS9,PRDX2,RPL35,TUBB,CHCHD3,PRRC2A,RPL19,GGH,YWHAZ,RPS5,SLC25A5,HSPD1,HNRNPA2B1,SLC39A3,PCNA,SRSF7,RPS24,ERP29,BAG2,G3BP1,RPS27A,SSRP1,RPL29,ERLIN2,RPN1,MOXD1,RPS11,RPL9,RPL8,PSMB5,PSMB4,FAM3A,RPLP2,SPTAN1,RPL7,ERLIN1,PPIA,SRSF10,OS9,PSMD3,PDIA3,PRDX1,HNRNPA1,HBA1,LYZ,RPL23,PGK1,LSM12,RPS15,RNASE1,HSPA5,MARS1,NTPCR,HBB,SAMM50,SSR1,UBE2M,LUC7L3,UQCRC2,RPS3,PSMA6,CALML5,MACROH2A1,SLC25A1,RPL7A,CFL1,RPS17,CHRAC1,ATP1A1,IGF2BP1,CALU,MAP1B,RPL3,TRAFD1,DHX9,PSMA5,HNRNPK,CSE1L,FKRP,EDEM2,CAPZA1,RPL17,LY6H,MTCH2,H2AX,SFTPC,CAPN2,SYNCRIP,RPL32,DSTN,RPS16,TMPO,ELOC,GAPDH,TPM3,TRAPPC2L,RPL24,RPS2,MAP4,RPL10A,XRCC5,TIMP3,RPS28,P4HA2,HSPA8,LCN1,DDX5,STAU1,ITGAV,RPL27A,CTBP1,MMP14,NUFIP2,LMBR1L,ATP5F1B,PSMD4,CBX5,PSMB6,RPL10,PSMA4,HMGCS1,CCT2,CHTOP,H1-10,RPS26,RPL31,ABCF1,PABPC1,TRIM21,RUVBL2,PDIA6,PSMA1,HNRNPF,PGAP4,RPL28,RPS4X,TMEM59,RPS7,EEF2,TUBB4B,ZRANB2,RPL18,RPS23,NCR3,FABP5,SRSF1,FUBP3,MAGED2,EED,S100A8,RAB1B,TCP1,RAMP3,CCT7,HSP90AB1,IFI16,RPL6,PPFIBP1,XPO1,PPIB,LCN6,CBL,DDX1,HSPB1 |
| 2.008e-19 | -43.05 | CFTR (CF transmembrane conductance regulator) | protein interactions | 1080 | 1469 | 565 | 19454 | 5460 |
ACTR1A,IPO8,IL1R2,UBL4A,PSMC3,TMEM165,NHERF1,TLR3,TRAFD1,RPL3,SLC16A1,SLC25A11,ATP2B4,FKBP8,CAPZA1,TMEM33,RASL10B,KPNA2,CAMKV,HTR5A,KLHL22,PGAM1,SELENOS,DNAJB2,ACOT8,TMOD2,RPL10A,FAM222A,RPS2,LCMT1,EEF1B2,RPS16,DNAJC1,FMOD,CFTR,NTPCR,SMYD3,CAPN1,SPTBN1,ACACA,ZNF770,PRKCA,IDH2,VPS4B,LCP1,PRDX6,HSPB2,HNRNPH2,UGDH,APMAP,MARS1,HSPA5,TOMM20,MRPL41,CLCA1,RPS17,SUB1,MAT2A,CABCOCO1,CALU,PTTG1,ATP1A1,EIF3G,EIF2S2,PSMC5,PSMA6,RPS3,TFEB,SUCLG2,PRKCE,ADRM1,GPX1,BUB3,SERPINA3,ISG15,RANBP1,PGAP2,RPL18,GNAZ,RND3,KDELR1,PDIA6,RUVBL2,FBXO11,CCT8,PABPC1,HNRNPDL,IL13,RPL28,KRAS,CBR4,PPIB,EEIG1,HSPB1,YWHAB,DRG1,FAAP100,CORO1C,S100A8,HOMER3,SERPINC1,FABP5,LANCL1,TOR1B,DYNC1I2,EIF2S1,CD59,PABPC5,RPL27A,SIGMAR1,UBAC2,STK26,RAB5A,HSPA8,XRCC5,SNRPA,GNB4,STAU1,RNF5,PCCB,EPS8,GABRG2,DNAJB6,ICAM1,OSGEP,H1-10,GTF2F1,GTF2F2,SCN2B,DES,TRIM29,PSMD4,ATP5F1B,RPL15,GGCT,YTHDF2,MRPL11,SERPINB10,ADRB3,SNAP23,SEMG2,EMC2,SEPTIN7,DLG1,KATNAL1,CLEC7A,SLC25A10,EIF3E,ARF4,CTNND1,RPS13,HSPE1,BACH1,TF,GLO1,HDAC6,GMPPA,CGB8,CALR,TIAM1,ESYT1,PSMD7,CRBN,PWP2,SEC23A,AIFM1,HACD3,SRP14,SLC25A12,CAV1,ATP5PD,TOP1,PPP1R18,EDF1,MX1,SNRPN,WDR83,RPS14,PSMC4,MTRES1,EPHX1,NOL7,RPLP0,HSP90B1,LMNA,JUP,ITGA2,SQSTM1,ARPC2,MAVS,VIPR1,CSTB,MYH2,RPL4,SMC4,GTF2I,B2M,TUFM,KPNA6,ATP5F1A,CTSD,CSK,XPOT,ATOSB,UBE2I,RPS20,RTRAF,GANAB,SCAMP2,GIMAP4,OPTN,STUB1,CYP4F12,RPL22,TECR,SH3BP4,RPL13A,LDHA,TXN,RAB14,GFPT1,MARCKSL1,FEN1,OTULIN,PLD3,UBE3A,JAK1,ARGLU1,HNMT,OSTM1,RFC2,SERPIND1,MCM6,ETFA,LASP1,STOML2,PRDX1,PSMD3,RPL23,LRRC57,AHSA1,RNF139,LYZ,CSTA,ADAT1,RPLP1,PBDC1,PHB1,PPP2CB,DNM2,ERLIN1,SPTAN1,CCAR2,RPL7,ATXN10,IDH3B,EHD1,TASL,RDH12,MYL6,APOC2,EPO,MED23,ATP5PO,NMRAL1,LUM,UNC45A,TNFSF10,SKP1,NFIL3,MCM4,SAMHD1,RFC5,IKZF2,TXNRD2,CUL2,CFAP20,EXOC8,LMNB1,MYO6,TAFAZZIN,RPL37A,AP2M1,EIF3K,RAN,FAU,ZNF22,OTUD6A,RPL19,TNPO3,CHCHD3,RPL35,RBBP4,SPRR1B,FGL2,TP53,RPSA,STRBP,SLC25A24,CAPN2,CAPZA2,SURF4,MEIOB,MAP1B,RPL17,RDH11,RAB3B,CSE1L,HNRNPK,AKAP12,PSMA5,ELOC,TPM3,GAPDH,ZDHHC15,SHC1,RPL24,RAC2,DSTN,RPL32,SSBP1,ACSL4,MYL12A,RPS27L,CAND1,VTI1B,CPNE1,CDC42,SSR1,HBB,MGP,DLAT,DERL1,PGK1,SEPTIN6,LIN7C,RPL27,GRPEL1,RPS15,DNAJC5,SLC35B4,CFL1,RPL7A,NUDT1,SLC25A1,PSMB2,TRIM32,DTL,CALHM5,SPEF1,EPCAM,CALML5,SEC61A1,UQCRC2,EEF2,RPS7,TUBA1A,RPS23,TAF10,SLC4A8,PDHA1,PLS3,TUBB4B,MYO1B,TRIM21,PRDM4,EWSR1,RPL31,GNA11,TFG,RAB18,RPS4X,MX2,RUVBL1,PSMA2,PSMA1,CTNNB1,ACTR3B,DDRGK1,TOR4A,YWHAH,YWHAG,XPO1,RAB5C,SLC38A7,WWP2,RPL6,SEC61A2,POU5F1,CBL,DDX1,DEGS1,GSTO1,PABPC1L,PSME2,HSP90AB1,SNRPD3,RPS10,CCDC167,PSMB3,DDX5,SF3B1,SPECC1L,GINS3,CHRNA7,ITGAV,EEF1G,PHB2,BAG3,PSMD1,SFN,LDHB,HNRNPC,PSMA4,SERPINH1,RPS26,GADD45B,PSMD14,CCT2,MCPH1,DLST,VDAC2,VEGFA,LMBR1L,RPL10,PSMB6,EIF4E3,TAX1BP1,TAGLN2,ACCS,CCT5,SERPINA1,SPSB3,ADAMTS1,ACTR2,PTGES,RPL23A,TCOF1,SFXN1,PPP1R12A,PTGES3,FARSA,HUWE1,ATP5MG,MOV10,ANKRD49,TES,PSMB1,RPL12,PTPN1,NCBP2,DERL2,RPL35A,FTH1,UQCRC1,KDELR2,UBA52,SEC22B,MREG,LIAS,WDR5B,RPL26L1,RARS1,KRT7,JKAMP,METTL14,CHMP1A,METTL2A,IDH3A,VPS28,CHMP2B,TTR,MGAT5B,HSPA14,IL2,AP2A1,ARFGAP3,MSN,ALB,RPS12,TRIM27,ENO1,CTNNA1,TUBA1B,CHRM4,GNAI2,SLC25A31,TMOD3,PNP,COPE,ERLIN2,FAF2,ACTN4,RPL29,PPP2R1A,RPS11,ITGB5,NME1,GDI2,RPN1,BAG2,HINT2,PCNA,HNRNPA2B1,ZYX,HSPD1,SLC25A5,FLOT1,SAR1B,AHCYL1,SACM1L,PSMD12,PDIA3,STX1A,HAX1,VPS4A,SKIC8,RPLP2,KRT8,PSMB4,PSMB5,RPL8,RPL9,TMEM237,TLCD4,PPIA,EGLN3,AGK,MYH1,PGRMC1,DAAM1,BEND5,GINM1,SLC25A3,ARCN1,ISOC1,VAPB,JADE1,EMG1,PSMA3,CALHM3,TRIM5,AZGP1,GSTT2B,PYGB,CDSN,NOP53,PCDHB8,YTHDF1,MED11,SEC22C,RAB11A,HSP90AA1,RPS5,YWHAZ,RPS9,SNRPD2,PNMA1,ERH,TUBB,SYNE4,ACTB,LGALS3,EIF4A2,PRDX2 |
| 3.311e-19 | -42.55 | KIF14 (kinesin family member 14) | protein interactions | 9928 | 1803 | 672 | 19454 | 5460 |
RPS23,LIMD2,PDHA1,H2BC1,CA14,TUBB4B,PLS3,EEF2,RPS7,NUP37,H1-3,HEXA,ETFB,ABHD6,TFG,UTP25,RPS4X,TCF23,PTPN4,HNRNPF,PSMA1,MYO1B,ABCF1,RPL31,GNA11,AVL9,DDX1,CDC23,TNNC2,PEX3,CRTAP,CTNNB1,TENM3,QPCTL,DDRGK1,NDUFV2,YWHAH,XPO1,YWHAG,RPL6,TSPAN10,IFI16,BAZ1B,DDX50,HSP90AB1,CCT7,SNRPD3,HNRNPL,RAB1B,RPS10,ECHDC1,PABPC1L,RBM5,FUBP3,SIN3A,RAB35,FAM81A,CSNK1A1,NUFIP2,MRPL12,EFHD1,USP6NL,PACSIN3,EEF1G,PHB2,NDUFS2,SRSF2,FXR2,TRA2B,DDX5,SF3B1,RPS28,SPECC1L,CD40,SERPINH1,CDKL2,RPS26,RALGAPA2,BAG3,CPSF2,SLC1A3,SNRPB,SFN,HNRNPAB,HNRNPC,RPL10,ESR2,POLR2B,CBX5,MATR3,MRPL13,RRAS2,SMU1,DLST,VDAC2,PAPSS2,NUPR1,GNAI3,BIRC5,SH3GLB1,CAPZA2,CBX3,RPSA,STRBP,RPL17,MPST,RDH11,MEPCE,STX11,CSE1L,HNRNPK,NUP107,DHX9,CYBRD1,TSNAX,AKAP8L,H2AC4,SHC1,RPL24,ELOC,TPM3,GAPDH,ROGDI,COX5A,TSPO,RPS27L,TMED9,FZR1,RAC2,EXT1,DSTN,RPL32,ALYREF,METAP1,SSBP1,ACSL4,LUC7L3,CSNK1G3,DDX4,HPS6,CD2AP,CDC42,AGO1,GTF2H4,FTSJ1,LITAF,WDR3,RPS15,DLAT,ARFIP1,GFM1,TNFAIP1,PML,RBM23,MAIP1,DDX46,RPL27,CDKN2AIP,IGF2BP1,ABCG2,CISD1,GORASP2,CFL2,MTPN,CFL1,RPL7A,TRIM32,RAB2A,SMARCA5,DYRK1A,RSL24D1,RPGRIP1L,DAPK3,MACROH2A1,CYTH1,GNAO1,TRAF7,TMA7,SF3B6,PSPC1,SART3,SNRPE,POLR2C,RPS11,EXOSC3,RPN1,ERLIN2,CCDC160,ACTN4,PPP2R1A,RPL29,CSNK1E,FLOT1,SSRP1,PSMD12,TMED7,SEMA4C,S100A10,RCVRN,BAG2,MRPS11,SRSF7,HNRNPA2B1,HSPD1,HNRNPD,MED4,MRPS26,WDR12,HNRNPA1,NDC80,HMGA1,RAB32,PDIA3,STK3,DHX15,PPIA,SRSF10,EGLN3,PSD2,INA,NDNF,KRT8,RPLP2,MRTO4,RPL8,RPL9,MFAP1,LARP4B,STXBP1,RASL12,DAAM1,ACTL6A,CCR7,AZGP1,TMED3,YTHDF1,TRIM5,SPOCK1,ILK,CCDC25,RPS5,RHOB,YWHAZ,RPS29,SMARCE1,PRPF31,PMPCA,PYCR1,TMED4,PKP4,ACO2,PRRC2A,ERH,MAT2B,GPR37,ACTB,EIF4A2,SEC61B,RPS9,SNRPD2,SNRPD1,GNG12,DHRS7B,NDUFS3,ACTR2,SIGLECL1,CD2BP2,CCT5,OSGEPL1,TMEM126A,SMN1,VRK1,FN3KRP,NLRP9,RPL23A,TCOF1,NKRF,TMED1,GARRE1,RAB1A,PPP1R12A,CLIC2,BRD3,OSBPL8,CNN3,TRAPPC4,POR,GRSF1,MOV10,CDK9,NCBP2,TOMM70,CGAS,MRPL50,RPL35A,RPL12,PTPN1,RPL26L1,HNRNPH3,PICALM,SEC22B,PCK2,SF3A1,TXNL4A,BRIX1,NF2,PDHB,CLK1,IDH3A,HELLS,RHOU,MAPRE1,AP2A1,ZSWIM7,RACGAP1,RPL26,VIRMA,GNAI2,JUNB,DEK,RHOJ,TMOD3,MGST3,COPE,MSN,ALB,RPS12,DNASE1L1,TRIM27,NEGR1,CTNNA1,ENO1,CTTN,TUBA1B,METAP2,CCNF,CRKL,RHOBTB1,RPL18,MTA2,KIF2A,SOX2,SUPT5H,TOP3B,HNRNPDL,CYP11B1,RPL28,HMGN4,VDAC1,KRAS,H1-6,PDIA6,RTCB,RUVBL2,EFNB1,TOP2B,PABPC1,CCT8,HSPB1,DRG1,YWHAB,STK4,UTP6,PPIB,PPFIBP1,RMND1,TCP1,LYAR,FAM98A,TRAPPC10,SPINT2,CORO1C,MAGED2,SRSF1,POLR2L,GNB3,FDFT1,PLAA,PAK2,RALYL,CD59,ESAM,TANK,PABPC5,RPL27A,GNB4,SSR3,STAU1,OXCT1,HNRNPA0,STK26,RAB5A,EP300,XRCC5,SLU7,LCA5,POLR1B,DNAJB6,FTSJ3,CHTOP,TMED5,DES,ATP6AP2,TRIM29,ATP5F1B,PSMD4,ANAPC2,PHF21A,BST2,SF3B4,RAB9B,FAM83B,PSMC3,IK,NEFL,ARPC3,CHAMP1,TFRC,ZMYM4,HADH,H2AX,MTCH2,TNRC6C,MRPL47,RAP1A,CAPZA1,KPNA2,TMEM33,SRPRB,RPL3,PALM2AKAP2,RPL10A,TMOD2,RPS2,SNRNP70,TUBG1,RBM17,KARS1,CDC5L,SURF6,DKC1,TMPO,RPS16,TRAPPC3,COMT,COX4I1,CAMLG,CD274,SYNCRIP,TRIM36,UTP15,IDH2,SAMM50,ZNF326,RPA2,CSNK1A1L,SDCBP,H2BC11,TRIM68,GTF3C4,SUMO1,SPTBN1,RBM22,KDM1A,PRDX6,HNRNPH2,POLD2,BANF1,ATP1A1,DNAJC10,LACRT,RAP2C,EIF3G,RPS17,GSTK1,RPF2,SRC,CSTF3,SUCLG2,RPL10L,RALA,MRPS21,BUB3,PLCB2,MRPS28,PSMC5,LIG3,RPS3,AP2S1,GNB1L,CTSA,DCUN1D3,FAM200A,NUP153,GFPT1,ASPM,FEN1,RFC3,PLPP6,RFC2,ETFA,TRIM37,G3BP1,RPS24,SLC39A7,ZC3H7A,ARGLU1,PPAN,RPL23,CAMSAP2,DDX23,RHOG,RAP2B,EIF3D,TRA2A,MMUT,SAV1,MRPS35,RAB3D,PRPF19,CLPX,CNTROB,ERLIN1,CACYBP,SPTAN1,RPL7,SNX2,KCTD10,NOP58,RPLP1,HP1BP3,PCBP4,PHB1,CCDC127,FOLR1,WDR6,MYL6,ADNP,ATP5PO,RND2,PPP1CB,MTX2,H1-5,G3BP2,UNC45A,TNFSF12,SKP1,COIL,NPTN,NUP50,CCDC86,HADHA,ATP5MK,MCRIP2,RIT1,LMNB1,MYO6,ATP1A3,MCM4,MCM3,RFC5,CUL3,CFAP20,NOP16,RPL19,SNRPB2,GNB1,CHCHD3,DYNLL1,RBBP4,RPL7L1,RPL35,AP2M1,VRTN,RPL37A,RMDN3,CYB5R3,PELO,RAN,CPSF1,MSRB3,SRP72,ILF2,UAP1,DMAP1,RPL15,YTHDF2,MTA3,PRDX4,MDC1,SNRPG,EIF3E,CTNND1,ARF4,RPS13,THRAP3,HSD17B10,PC,HAPSTR1,ZC3H11A,DLG1,SDHAF1,FGR,SSX2IP,MPHOSPH10,MFN1,MPG,HDAC6,KLHL9,ZBTB2,G6PD,CAV1,TOP1,MAPRE2,PPP1R18,PWP2,CTDSPL2,AIFM1,H2AZ1,SRP14,MACROH2A2,RPLP0,ZNF574,TMOD1,HSP90B1,MRPS34,LMNA,JUP,P3H1,CDK1,CNP,FAXC,MYL12B,SAP30BP,ATG16L1,RPS14,CRYZ,POLDIP2,RPL4,GTF2I,EIF5B,EGFL7,SQSTM1,H2BC12,ARPC2,PRPF4,SIRT7,MME,NCKIPSD,NAPA,PPP1CC,TUFM,NONO,ATP5F1A,RPL22,SH3BP4,TECR,RPL13A,YES1,ARMC6,MAGOHB,RAB14,RPS20,CHCHD6,ACAT1,GANAB,RTRAF,TMEM74,TNFRSF1B,EIF4A3,HYCC1,INPP5K |
| 3.351e-19 | -42.54 | regulation of programmed cell death | biological process | GO:0043067 | 1569 | 620 | 18204 | 5365 |
AIFM1,AKT1,NOP53,NDNF,SIAH2,TGFB3,IL1B,CALHM2,ZMYND11,LMNA,MIR182,WNT7A,RPL26,SLC25A31,SELENOS,SMAD4,TLR6,PIK3R3,NAA16,MIR675,CALR,BOK,IGF1,CERS6,PTRH2,PDCD10,VDAC2,SGMS1,UCP2,MT3,GPX1,PNMA5,CTNNB1,TNFAIP3,SLC1A1,VDR,BAK1,CTSK,HYAL2,GSTP1,FAS,EIF2AK2,MLLT11,KIT,ANP32B,MTRNR2L3,GNAI2,AATF,XBP1,MIR320A,MET,HTRA1,SOD1,RRN3,AR,TRIM24,CNR1,CAAP1,UBE2M,PSMG2,CCND1,TSC22D3,PAK2,MIR221,MIRLET7B,STK26,IL2,MIR125A,B4GALT1,STAT1,NRP1,PCSK9,LRP6,BCL2L1,MORF4L1,LIMS2,JAK2,STXBP1,G0S2,BAD,DEDD,PARL,AKR1A1,TEX261,SYVN1,TMEM215,EGLN2,ACER3,HSPD1,ENO1,CD274,VDAC1,DMAP1,MIR186,ACTL6A,RNF122,JUN,PPARA,PELI1,TMBIM1,TRAF7,DAPK3,PAK5,TMEM196,HAX1,PRNP,CLIP3,MIR449A,IL12B,KPNA1,FOXP1,NKX3-2,PEA15,ACVR1C,MIR223,ACAA2,RTKN,MIR107,MMP9,BTG1,UBB,GADD45G,ERP29,TP53INP1,BAX,STAMBP,IL6,ZBTB16,GPRASP3,MAEA,MYBL2,RGCC,UBE2B,RPL10,MCL1,TIA1,ATG7,DNM2,TNFRSF1B,HDAC3,RTN4,MIR21,MIR30B,CDC73,PPP1R10,DNAJC3,MIR375,NACC2,MSX2,SFN,DNAJB6,BCL2A1,SERPINB9,MIR204,TXNIP,DSTYK,WNT10B,SIN3A,HYPK,CASP12,HHIP,NDUFS3,MIR210,UCN,PMAIP1,ANXA4,TPT1,SAV1,TXNDC12,TMEM164,TMBIM6,CD40,SYK,CLU,NLRP1,BFAR,TMIGD1,CREB3,CCAR2,FBXW7,NKX3-1,ATF3,RGL2,AKR1B1,NME2,S100A8,FCGR2B,NOG,RPS7,ZDHHC17,MIR24-1,MIR101-1,SMAD3,IFIT2,SLC7A11,SARM1,LAMP3,PTCRA,BIRC2,TFRC,LACRT,EGLN3,TRIM32,TAF9,GPAM,PDCD1,MAGEA4,G6PD,GADD45A,TRAF6,POU3F4,MIR222,NAE1,CYP1B1,CD2AP,CD38,PPIF,SYCE3,CTLA4,CCL19,VPS54,PIAS1,NUP62,PML,BMPR1B,NPPC,MAP2K6,NHERF1,DUSP6,HCLS1,CCL2,PSMC5,ARG2,EIF2S1,DCUN1D3,SPATA2,MIR16-1,NFKB1,PIH1D1,CRADD,TERT,SRC,PPID,ANGPT1,TRIM35,XPNPEP1,FAIM,TNFSF12,PNMA1,NME1,RB1CC1,FAM162A,KRIT1,MIR140,PIK3CG,ATF4,LEP,HNRNPK,FASLG,TNFAIP8L1,CD40LG,SQSTM1,PHB2,BACE1,SERINC3,ICAM1,APEX1,TCIM,NTF4,IFNG,BIRC5,PIK3CA,CDSN,MIR15A,ROCK1,PDCD4,PRKRA,DNAJC5,CTNNBL1,BRMS1,MIR30E,YWHAZ,PIK3R1,NR2E1,RXFP2,EIF2B5,NDUFAF4,NTRK2,NIBAN2,AREL1,CAPN2,DDAH2,PRELID1,MIR181C,BMPR1A,VSTM2L,SIGMAR1,MECP2,IVNS1ABP,HSPB6,HIGD2A,MIR137,NFE2L2,FBXO7,TIMP1,NF2,BNIP3L,MIR29A,CCAR1,CD248,VEGFA,DKK1,SDF2L1,FEM1B,GCLC,SOX2,CEACAM5,HAND2,MTDH,TNFSF18,GREM1,SEMA5A,CCR7,IL1A,TGFB2,CRYBA1,SRPK2,DPEP1,NOTCH2,KRAS,PLSCR3,PDE1A,TLE1,NCK1,FGF10,LTB,CTNNA1,BAG3,FZD3,CCR5,SOX9,CBL,GPX4,MIR20A,GHRL,RGN,CCL21,CSNK2A1,SLC35F6,IGBP1,ADAMTS20,CHST11,BECN1,SNAI2,LTBR,FIS1,ACTN4,CTSB,KDM1A,ING5,MIR29C,IRF7,MAD2L1,COPS5,TWIST2,LTA,IRF8,PRMT2,SHC1,MIR132,BCL10,HTR2A,IL12A,SCG2,PELI3,CDK1,TPD52L1,LILRB1,CNTFR,FRZB,PDCD5,MIF,HNF1B,CCL3,RNF34,CDK5R1,MTCH2,CFL1,STK3,DAD1,CSF2,SMAD5,IL6ST,HEY2,IRF3,MAP3K12,USP15,HSP90AA1,TLR3,MIR200A,DDX42,AKAP12,IL2RB,GLO1,GBE1,DLX1,MIR106B,KCNB1,CCL5,CDC42,HSPB2,DAPK1,PPIA,HSPB1,CRYAB,PRDX3,NUPR1,MIR142,SOCS2,ZFAND6,FBXO11,MYC,SNCB,IER3,SFRP1,FLCN,IGF1R,CREB1,MIR126,IFT57,BRCA1,IL4,GADD45B,HTRA2,HSPA5,PSEN1,MIR146A,ARL6IP5,FXN,IGFBP3,MEAF6,EEF1E1,SOCS3,IFNB1,CAV1,ST3GAL1,MEF2C,ING2,TNFAIP8,RUVBL2,CDKN2D,PIM2,AGAP2,HSP90AB1,PTPRZ1,TAX1BP1,CD28,PLAC8,BCL6,PNMA3,CXCL12,PNMA2,KCNMA1,CDK5,MIR495,ORMDL3,HMGB1,DFFA,STUB1,PYCARD,HRAS,MIR23A,ZNF304,MIR361,RHOB,PLEKHF1,MIR98,EMILIN1,CXCR4,CX3CL1,RAF1,SLC39A10,IL10,PPT1,PTGFR,ACTB,MAP3K11,DDRGK1,TNF,ADIPOQ,NAA15,RUVBL1,PDIA3,PHB1,ING1,RPS3,SLC25A4,ANP32A,TRAF1,MSX1,CX3CR1,TRAF2,MIR145,DBH,AIPL1,ACVR1,NEFL,PRKCA,RNF144B,MIR214,MIR17,CTSD,UFM1,MIEN1,ALDH1A3,SLC25A27,FOXC2,SPHK2,RBM5,HSP90B1,CDKN1A,ZNF622,CIDEB,PSMD10,CXCL10,CFDP1,PTPMT1,RB1,CTTN,CITED1,ADNP,OGG1,SLC25A5,NPY5R,STRADB,CASP4,ASIC2,RAG1,PTPN1,ADORA1,CSRNP3,HSPA8,FGFR1,ITGAV,ACKR3,PCGF2,PRDX2,MGMT,MIR26B,SAP18,ARF4,TFPT,NONO,GHITM,EYA3,IFI6,TLR4,DDIT3,KLF4,TOMM70,SMG9,TMEM14A,MIR590,STK4,IDO1,LCMT1,ERCC3,TP53,ST6GAL1,FKBP8,MAEL,CTSC,API5,TNFSF10,LPAR1,MDM2,DIPK2A,SOD2,SLC39A7,MIR34A,IL13,VPS72,MITF,ITGA6,MIR1-1,CLEC7A,PRKCQ,TNFAIP8L2,PPP2R1A,NAA35,TNFAIP8L3,HELLS,NQO1,TSPO,BTG2,CDKN1B,CD3G,FATE1,SFRP4,FCMR,UFL1,PPARG,RETREG1,EGR1,RBCK1,SIAH1,MIR28,CLN8,NR4A2,LGALS3,RAD21,MNAT1,EPO,FSTL1,IL7,MTRNR2L7,MIR198,MIR195,FAF1,PYCR1 |
| 3.374e-19 | -42.53 | ORF3a (ORF3a protein) | protein interactions | 43740569 | 789 | 336 | 19454 | 5460 |
AP2M1,CYB5R3,SLC23A2,NDUFAF4,DYNLL1,REEP4,UMPS,LGALS3,LRRC8A,RHEB,TOMM40,PYCR1,RAB11A,HSP90AA1,PFDN2,SCFD1,WDR20,LMNB1,RHOB,MYO6,BLVRA,TTC1,VLDLR,NMRAL1,STX7,SRM,PGRMC1,NOTCH2,CA12,GINM1,FAM234A,NDUFA5,SLC25A3,FKBP1A,PSRC1,FKBP10,ARMCX3,VPS18,H2AC1,VAPB,USP39,SNX17,CYB5A,MCOLN1,NEO1,MRTO4,THOC2,TMEM237,RAB11B,TMEM248,SNX1,SPTAN1,SNX2,VPS26A,STOML2,RAB3D,RAB32,PDIA3,SLC20A1,COTL1,GAL3ST1,SCD5,NDUFA4,GOLGA7,SACM1L,AHCYL1,TMED7,SEMA4C,ATP5F1D,ACVR1B,KIT,IFNGR1,ACTN4,PPP2R1A,ACO1,MARCKSL1,MFAP3L,MACO1,CSNK1E,TPBG,PLD3,STX12,STIM1,VAMP2,VPS33A,RPN1,ODR4,MSN,ACAT1,GSK3A,GANAB,DTYMK,SCAMP2,CYRIB,VAMP3,SULT1A3,STUB1,DDAH2,TECR,YES1,SNX3,SLC25A4,PNP,MGAT1,ABHD17A,RAB14,NRSN2,HMOX2,FLRT3,CYRIA,CREB3,MAPRE1,AP2A1,EPHA2,BMERB1,NAPA,SPCS2,MTDH,LRRC8D,TMUB1,USP8,CERS2,YKT6,B2M,GABARAPL2,CNP,SIPA1L1,EEF1E1,UBA52,SEC22B,DDAH1,ADIPOR1,ARHGAP1,RABL3,MET,SH3GLB2,HSP90B1,PICALM,GOLGA5,GHITM,JUP,CDCA3,LDLR,DLGAP4,PTPN1,HACD3,SRPRA,NKIRAS2,NCBP2,TOMM70,TOP1,GLO1,HM13,PMM2,BMPR1B,GRSF1,RELL1,MICB,CALR,OSBPL8,TRAPPC4,PPIC,POR,SNAP23,CLTRN,HINT1,DLG1,LTBR,RAB1A,SLC25A10,VPS16,GALNT2,CTNND1,ARF4,HUWE1,PGM1,SELENOK,NDUFA2,YTHDF2,CCDC47,TMEM156,HSPA13,LRP12,EFHD2,SRXN1,VDAC2,MYRF,ALG5,TOM1L1,IREB2,GPNMB,TAX1BP1,NDFIP1,MLF2,TBCE,SERPINH1,MDH1,ZMPSTE24,SLC38A1,CKB,LAMTOR1,RAB5A,DDX39B,BMPR1A,SAP18,UFL1,EDEM3,BORCS6,DHRS4,IL6ST,UBL3,USP6NL,PIP4P2,CSNK1A1,CNDP2,AKR1A1,ACAA2,TRAPPC10,SPINT2,STX5,PCDH9,RAB31,RAB35,HSP90AB1,TOR1B,VAMP7,DYNC1I2,EIF2S1,RAB1B,DDRGK1,PPIB,YWHAG,XPO1,WWP2,PFDN5,RAB5C,DDT,NCK1,IKBKB,PDIA6,MYO1B,LSM14A,VAMP8,CCAR1,VDAC1,KRAS,EEF2,HPCAL1,PCDH19,GCLC,NETO2,GNAQ,HGS,CLDN12,PTRH2,NUDT19,EPCAM,STX10,SEC61A1,NECTIN2,DUSP3,TXNDC12,RALA,GORASP2,PCBD1,SLC6A6,ARL6IP6,MTPN,PTPN11,RAB2A,VPS39,SORD,ATP1A1,GLOD4,HFE,DLAT,RAB9A,ITM2B,NBN,LRP10,APMAP,CLU,GRPEL1,GCNT3,NAPG,PLP2,SLC4A10,CDC42,AKR7A2,SPTBN1,CSNK1G3,CHPF2,SSR1,WWP1,FGFR1,TRAPPC3,AKR1B1,CAMLG,STT3A,ITGA6,GLT8D1,CD99L2,RBM42,STX6,ST3GAL5,SNAP25,RPS16,DNAJC1,VTI1B,ARL6IP5,COX5A,KARS1,RPL10A,H2AC4,SHC1,SLITRK5,IDH1,RAB13,ERO1A,ATP2B4,DDR1,FKBP8,CSE1L,TGFBR2,TMEM33,SRPRB,NDST1,CD38,SYNGR3,FURIN,GNAI3,UGCG,BMPR2,ACVR1,TFRC,GOLGA7B |
| 3.384e-19 | -42.53 | TNIP2 (TNFAIP3 interacting protein 2) | protein interactions | 79155 | 949 | 391 | 19454 | 5460 |
MOV10,DAG1,CNN3,TIMM8B,RPL12,WDCP,PSMB1,MRPL50,RPL35A,CWC15,NCBP2,SELENOK,CCT5,TIMM8A,NDUFS3,CIBAR1,NKRF,GARRE1,PPP1R12A,CPNE2,PTGES3,RIGI,TAF5L,CTTN,RPS12,TRIM27,ZBTB18,PNP,COPE,VIRMA,JUNB,MED30,PIGW,WTAP,HNRNPH3,UBAP1,RPA3,SOD1,KIN,CLK1,NF2,PDHB,LSM8,VPS28,CHMP2B,ATG9A,HNRNPA1,SKIC8,MRPL18,STX1A,PSMB4,KRT8,RPLP2,NDNF,DHX15,PPIA,ANP32A,B3GNT2,JUN,ACTN4,BZW2,RPN1,SART3,POLR2C,RPS11,POLR2D,HNRNPA2B1,SLC25A5,BAG2,SKA1,SRSF7,SLC17A5,PCNA,TNF,GOLGA7,FLOT1,PYCR1,PKP4,MAP3K21,ZCRB1,MED10,HTRA2,PFDN2,HSP90AA1,CNIH4,PFDN4,POLR2F,TUBB,ACTB,PRRC2A,ERH,CDKN1A,BIRC2,YTHDF1,MED11,ENY2,EDC3,GAPDH,SMCHD1,ALYREF,EXT1,MIF,SPPL3,SLC38A2,RPSA,CAPZA2,CBX3,BHLHE40,DHX9,PSMA5,CCNB1,PSMB2,MLF1,ARHGAP21,CFL1,IGF2BP1,OAT,TMA7,SF3B6,PSPC1,CSNK2B,CYTH1,CALML5,TXNDC12,DAPK1,EIF4H,CDC20,WWP1,SSR1,LUC7L3,TFIP11,TXNDC17,TMEM263,PPP1R26,ZBED3,PSMG4,RPS15,WWP2,TENM3,NGDN,YWHAG,XPO1,CRTAP,RIMKLB,MAGOH,DDX1,FUBP3,WDR82,HNRNPL,HSP90AB1,CCT7,NUP37,TAF10,RPL31,EWSR1,RUVBL1,KGD4,HNRNPF,CBLL1,TFG,HS3ST3A1,HNRNPAB,HNRNPC,PSMA4,COX6B1,MYC,CPSF2,CUTA,S100A11,CKB,CCT2,RPS26,DLST,DKK3,SMU1,HDDC2,MATR3,TAGLN2,POLR2B,ZC3H14,GLRB,MRPL12,QTRT2,ACAA2,EIF4B,DDX39B,NGRN,DDX5,EEF1G,PHB2,FXR2,TRA2B,SRSF2,TLE1,NFKB1,GLO1,MPHOSPH10,RCHY1,AIFM1,SEC23A,ATP5PD,TBK1,CCDC47,AGPAT5,EEF1A1,SAP30L,ZFAND2A,ILF2,HINT1,HSPE1,TOM1,THRAP3,PAK1IP1,PRDX4,FBXO25,CTNND1,PYCR2,SEC13,EMILIN1,PPP1CC,TUFM,NONO,TADA3,ZNHIT3,CASC3,STK11,GUCY1B1,LURAP1,EIF4A3,STUB1,ACAT1,RTRAF,RPL13A,MMD,LDHA,TECR,CPSF4,MYLIP,PSMC4,RPS14,SIPA1L1,HSP90B1,CDK1,CSTB,CCSAP,ARPC2,HMGB1,NUCKS1,TMEM209,ZBED4,PRPF19,TRA2A,CSTA,RPL23,BCL2L1,LYZ,PHB1,WDR6,RPLP1,TSG101,SPTAN1,KCTD10,NDUFS8,MARCKSL1,SAP30,GFI1,RBM38,EZH2,MOXD1,SSBP3,CDK5R1,EIF1AX,MRFAP1L1,RPS24,ZC3H7A,ETFA,LASP1,RBBP7,EMC8,EIF2D,ANP32B,SRSF4,CUL3,NDUFB6,MCM3,OTUD7B,SAMHD1,LMNB1,FAM221A,EIF3K,PARP2,CPSF1,DYNLL1,RPL19,GNB1,WDR77,PPP1CB,TIMM13,PRDX3,PPARG,NDUFA5,WBP2,HADHA,ATP5IF1,NAP1L3,WASF3,SKP1,PSMC1,PGAM1,KARS1,SNRNP70,RPL10A,SYNCRIP,EEF1B2,SDHB,PRELID1,SNAP29,ACTR1A,RPAP2,WBP11,NEFL,PSMC3,SELENOF,ATP5PF,STX18,RBCK1,CAPZA1,GSKIP,SUB1,CEP85,TNFAIP3,PCBD1,ATP1A1,PSMA6,MRPS28,EIF2S2,PSMC5,ADRM1,GPX1,SRPK2,CSTF3,SMURF1,CAPN1,SPTBN1,NTPCR,SDCBP,VPS4B,RNF113A,HNRNPH2,RBM22,PPIB,IKBKB,SRSF1,TCP1,DYNC1I2,EIF2S1,FAM98A,SUPT5H,CSTF2T,TRAF2,SMNDC1,TLNRD1,ALKAL1,CCT8,PABPC1,RTCB,RUVBL2,HNRNPDL,COX11,LDB1,NFKBIA,SF3B4,PSMD6,PSMD4,ATP5F1B,PPP5C,TANK,NUP62,PABPC5,SMIM13,SDC2,TPD52L1,XRCC5,SNRPA,EP300,MRPL34,SPATA2L,EIF1B,HNRNPA0,SAP18,MT2A |
| 4.887e-19 | -42.16 | RNF4 (ring finger protein 4) | protein interactions | 6047 | 1410 | 544 | 19454 | 5460 |
NAA35,PREB,MTCH2,IPO8,UBIAD1,TMEM205,ZMYM4,ZMYM3,GDE1,TFRC,CHAMP1,NFE2L2,ACVR1,TMEM165,TAB2,TBC1D4,PHC1,TAF2,SNIP1,RUSF1,STX18,RAB27A,RPL3,SLC16A1,MAN1A2,SRPRB,L1CAM,KPNA2,TMEM33,DNAJB2,ZNF24,SELENOS,CDK12,RPL10A,STT3A,CAMLG,COMT,COX4I1,DNAJC1,ARL6IP5,TWSG1,TMPO,ILVBL,SPTBN1,SUMO1,PPP1R8,UBE2W,GTF3C4,PLP2,CD46,ZNF326,USE1,TMX2,APMAP,ZBTB6,UBE2K,HSPA5,ZNF322,MARS1,MORF4L1,DNAJC10,ANAPC4,ATP1A1,CREB1,RPS3,ATL1,PAFAH1B3,ZBTB33,PSMC5,CYBC1,ZNF655,TRIM54,GPX1,PPP1R10,SRPK2,TRAF2,GLE1,CRELD1,RPL18,KLHL12,NDUFB5,RINT1,TOP2B,FBXO11,EFNB1,RABGGTB,SEC11A,PDIA6,ZNF609,SSNA1,RERE,UBE2E2,TBC1D5,IQSEC1,FAM20B,HSPB1,NDUFB8,PTK7,FABP5,MPDU1,NKX3-1,PGR,VAMP7,TMEM97,RMND1,LANCL1,RPL27A,GOSR2,EHHADH,PAFAH1B1,SEC22A,ZNF362,CD59,SIGMAR1,UBAC2,GAMT,FDFT1,PTRHD1,XRCC5,P4HA2,HSPA8,UBE2D3,HNRNPA0,RER1,SSR3,TMEM38B,SPCS3,RBBP8,H1-10,RBM27,MCAT,ZNF189,SF3B4,PSMD4,ATP5F1B,PSMD6,TIMM21,ATP6AP2,DES,SLC29A1,LBR,DDX39A,AGPAT5,THAP1,RPL15,UBE2B,ILF2,NSDHL,STX8,HINT1,TMX3,CAMK2G,THRAP3,CCL2,GALNT2,EIF3E,MDC1,CALR,ORC5,EI24,EMC4,BAK1,MFN1,ZMYND11,SLC2A1,ESYT1,CD9,H2AZ1,HACD3,HSD17B11,ALCAM,CD151,TOP1,PRNP,AKAP17A,CAV1,NOP9,PLGRKT,FUT8,VGLL2,EIF3J,JUP,CDK1,LMNA,TMX4,GHITM,HSP90B1,ZNF574,EPHX1,FADS2,SYVN1,ITGA2,SQSTM1,MTDH,CERS2,DESI1,RPL4,HMGB1,TMEM209,SLC5A6,NTAQ1,AR,NONO,TUFM,XPOT,CA2,REEP6,PELP1,VAMP3,CYRIB,SCAMP2,GANAB,UBE2I,RAB14,MGAT1,CD47,TECR,SEC63,TPBG,TMT1B,YIPF3,STIM1,AP2S1,CYB5B,PLSCR1,TMT1A,SLC39A7,RPS24,EMC8,LAMB2,RBBP7,PSMD3,MARCHF5,EMC6,TRA2A,RHOG,UBE2D1,LYZ,CDKN1B,BCL2L1,THOC2,PHB1,XPO5,CYB5A,HP1BP3,NOP58,ERLIN1,RAB11B,FAM234A,TMUB2,MED23,PCLAF,FAM3C,TSR3,NPTN,NSFL1C,GPC1,USP13,RRN3,CUL3,ZNF668,RBM15B,SLPI,LMNB1,EXOC8,SP1,ZNF22,RAN,CYB5R3,PIGK,SLC30A7,RPL35,TSN,MAD2L1,TNPO3,RPL19,PARL,SNAPC5,ZNF581,CBX3,SURF4,DDX42,GNAI3,MYD88,ZNF451,BCAP29,DHX9,YIF1A,PSMA5,NUP107,NEDD8,H3C1,HNRNPK,CSE1L,MEPCE,CTSC,RDH11,RPL17,TSPO,USP3,DHRS7,CD81,GAPDH,ZNF473,NUS1,ITGA6,ACSL4,UBE2N,RPL32,MGME1,SLC39A10,GNPAT,TMED9,VTI1B,UBTD2,LMAN1,GTF2H4,CDC42,TFIP11,CYC1,LEMD3,RPL27,TEX264,MAIP1,PML,DERL1,WDR3,SMARCA5,RAB2A,ATF4,RPL7A,ARL6IP6,CFL2,ATP1B3,MECP2,UBE2E3,ENDOD1,RBM7,UBE2H,CDIPT,CCSER2,TRAF7,B4GALT1,CALML5,SEC61A1,PPP2R5E,MACROH2A1,TXNDC12,CDC20,DYRK1A,ABHD6,NCSTN,RPS7,EEF2,PTRH2,HGS,RPS23,RPL31,PSMA2,HNRNPF,RAB18,TFG,CBLL1,RAB8B,IFI16,BAZ1B,LAMP2,PTDSS1,RAB5C,XPO1,DDRGK1,QPCTL,CTNNB1,FAM241A,ARL14EP,FAM241B,DEGS1,CBL,DDX1,RAB35,SIN3A,ZNF436,GYS1,STX5,RPS10,HNRNPL,PEX13,ZNF740,SUMO3,SNRPD3,SUMO2,HSP90AB1,USP6NL,BET1,SEC62,LXN,NUFIP2,JAGN1,CD40,DDX39B,TMEM106B,SF3B1,MIA2,DDX5,PHB2,EEF1G,ITGAV,MYC,APOBEC3B,HNRNPC,HNRNPAB,PSMD1,STX16,H1-1,ZMPSTE24,SERPINH1,VDAC2,ZMYM2,RETREG3,PRMT5,STAT1,MATR3,ZCCHC7,CBX5,APEX1,NCKAP1,ALG5,RPL10,NRM,TOPORS,ZBTB26,SOD2,RAB1A,TCOF1,NKRF,RPL23A,CCNY,IGF1R,NOC4L,FASTKD5,TUSC3,RIGI,HM13,DAG1,ATP1B1,POR,OSBPL8,ZNF652,LDLR,TNKS,RB1,MSMO1,SEC22B,SLC35E1,SLC12A2,ZCCHC17,GOLGA5,STOM,RARS1,HNRNPH3,SOD1,ZNF319,ZKSCAN1,GLIPR1,CLK1,RTN4,SPCS2,SLC7A1,PIAS1,DAD1,PEX26,TMUB1,CNTNAP1,ZNF687,HMOX2,SDF2L1,AP2A1,HERC4,GGCX,CTTN,ENO1,GTF2A1,MGST3,SCML2,VIRMA,ZNF263,RPL29,ACTN4,FAF2,RPN1,NDUFS6,ITGB5,STX12,SLC25A5,HSPD1,GPAA1,HNRNPA2B1,FAM76B,HINT2,SCD5,GTF3C3,UBE2A,SACM1L,GOLGA7,FLOT1,PDIA3,HMGA1,NDC80,HNRNPA1,PEDS1,STX1A,TMEM30A,HNRNPD,RPL8,ZNF664,RPLP2,PPIA,DHX15,TMEM237,CA12,PGRMC1,NOTCH2,AGTRAP,CDKN1A,VAPB,ELOVL1,SLC25A3,ATP2C1,HSDL1,TBC1D24,CYFIP2,STX7,PXMP2,ZNF250,TM9SF4,ELMOD2,BAX,SLC7A11,VMP1,SEC61B,SPCS1,ACTB,LGALS3,REEP4 |
| 5.389e-19 | -42.06 | LGALS9 (galectin 9) | protein interactions | 3965 | 584 | 263 | 19454 | 5460 |
RUVBL1,TFG,RPL28,RPS4X,TOP2B,PABPC1,CCT8,GNA11,SEC11A,PDIA6,RTCB,KDELR1,PTRH2,PLS3,HGS,RPL18,RPS23,RPS7,EEF2,NCSTN,FAM98A,EIF2S1,CCT7,HSP90AB1,VAMP7,FUBP3,HDHD5,CD63,MPDU1,PCDH9,FKBP4,YWHAB,DDX1,RPL6,LAMP2,BAZ1B,CTNNB1,XPO1,SLC38A9,PHB2,EEF1G,ABCC5,RPS28,DDX5,HSPA8,PALS2,ZER1,TOMM22,YIPF5,TAGLN2,ATP5F1B,RRAS2,PRMT5,H2AZ2,LAMTOR1,CKB,SERPINH1,SLC38A1,LDHB,HNRNPAB,SLC1A3,PCCB,HNRNPK,KPNA2,TMEM33,NUP107,RPL17,ATP2B4,SLC25A11,DHX9,RPL3,SLC16A1,SURF4,TFRC,TFCP2,GNAI3,SLC25A24,TSPAN3,RAP1A,MTCH2,RPSA,RPS16,CAND1,SLC38A2,SYNCRIP,EEF1B2,SNRNP70,SMCHD1,RPS2,GAPDH,HSPA5,MARS1,ABCC2,TEX264,DERL1,RAB9A,PRDX6,GFM1,DLAT,RSAD2,SDCBP,RPA2,ACACA,SPTBN1,CFTR,RALA,ACP2,RPS3,UQCRC2,CDIPT,SLC1A1,MACROH2A1,ATP1B3,ATP1A1,OAT,IGF2BP1,PTPN11,RPL7A,RAB2A,SLC25A1,RPF2,ST13,SLC6A6,CNNM4,TIA1,G3BP1,RRAGB,FLOT1,SSRP1,HNRNPA2B1,SLC25A5,OSTM1,HSPD1,SLC17A5,PCNA,NME1,GDI2,ENPP4,RPS11,STX12,RPL29,ACTN4,PPP2R1A,SPTAN1,RPL7,NOP58,CACYBP,PPIA,PHB1,RPL9,WDR6,RPL8,ATP6V1A,TSG101,NCR3LG1,CD58,RPL23,HNRNPD,STOML2,PDIA3,PRPF19,PRDX1,ATG9A,RAP2B,HNRNPA1,SRI,NPTN,LUM,ATP5PO,USP39,ABCB1,ANXA7,SLC25A3,MYL6,PRDX3,IDH3B,ACTB,LGALS3,LAMTOR3,LRRC8A,PRDX2,RAN,CYB5R3,SLC23A2,RPS9,SEC61B,YWHAZ,LMNB1,HSP90AA1,SCFD1,SLC7A11,TOMM40,MRPL16,FARSA,EIF3E,PRDX4,CTNND1,SFXN1,SLC25A10,HSD17B10,PC,SNAP23,LPAR2,CASK,RPL15,SLC29A1,LBR,EEF1A1,CGAS,TOP1,ALCAM,RPL35A,CAV1,HACD3,HDHD3,SEC23A,ESYT1,SLC2A1,H2AC14,ATP1B1,DAG1,HM13,SMC4,RPL4,PDHB,SLC7A1,TMEM209,BRIX1,SLC5A6,PNO1,CSTB,SQSTM1,SPCS2,SLC12A2,HSP90B1,JUP,RARS1,HNRNPH3,MET,ATG16L1,RPS14,UQCRC1,SLC25A4,CD47,RPL13A,TXN,MGST3,LDHA,DEK,RPL22,TECR,EIF4A3,OPTN,ACAT1,GANAB,RTRAF,LGALS8,CHORDC1,NONO,HMOX2,TUFM,PPP1CC,ATP5F1A |
| 5.696e-19 | -42.01 | LRRC59 (leucine rich repeat containing 59) | protein interactions | 55379 | 797 | 338 | 19454 | 5460 |
CAMLG,CD274,STT3A,COQ8A,RAC2,XXYLT1,RPS16,DNAJC1,ARL6IP5,CAND1,FZR1,LMAN1,CNIH1,TMPO,STX6,SELENOS,DHRS7,KARS1,DPP4,CSNK2A1,RPL24,SNRNP70,RPL10A,RPS2,PCYOX1L,DHX9,BCAP29,RPL3,STX18,ERO1A,RAB3B,HNRNPK,SRPRB,NUP107,RPL17,FKBP8,RPSA,SNAP29,UBL4A,PREB,TFCP2,TFRC,RNF8,SLC25A24,ZBTB33,ATL1,UQCRC2,RPS3,PSPC1,CSNK2B,SRP54,DHRS13,SRC,RPL7A,CARS1,GORASP2,RPS17,RC3H2,DNAJC10,UBE2H,CALU,IGF2BP1,ATP1A1,RAB29,APMAP,BAP1,TEX264,RPL27,RNF113A,DERL1,RAB9A,EXOSC4,RPS15,HSPA5,ZC3H15,TRAM1L1,CFTR,CDC42,SSR1,USE1,EIF2B3,RPA2,LEMD3,CYC1,RAB35,PTK7,STX5,CORO1C,RPS10,TMEM97,TSPO2,UQCRH,RPL6,WWP2,RAB5C,PTDSS1,PLPP4,LAMP2,DDRGK1,PPIB,NDUFV2,AGR2,H2BC17,PABPC1,RINT1,ABCF1,RPL31,CYP2C9,PDIA6,SEC11A,EWSR1,SETD4,RUVBL1,TMEM60,KRAS,TOMM6,FKBP2,RPS4X,STBD1,EEF2,RPS7,MSX2,DNAJC25,ISG15,NCSTN,CCDC134,RAB4A,PDHA1,RPL18,TAPT1,VDAC2,LMBR1L,ANAPC2,GGT7,ATP5F1B,USP16,RPL10,ESR2,ATP6AP2,SFN,TMEM38B,MYC,COX6B1,BTF3,SPCS3,SERPINH1,ZMPSTE24,PYM1,RAB5A,HSPA8,SF3B1,P4HA2,STAU1,PHB2,UFL1,EMC1,ARMCX2,BET1,TOMM22,CNPY3,SEC62,FKBP14,UBAC2,PIH1D1,NUFIP2,EHBP1,PTPN1,RPL12,HACD3,SRPRA,CDCA3,CHID1,HSD17B11,EIF2B5,ARF6,ZBTB2,CDK9,LAMTOR2,SPATS2L,EMC4,SLC25A46,EI24,MOV10,CALR,TMEM199,TMBIM6,MPG,LAMP3,HM13,HDAC6,ESYT1,POR,PPIC,OSBPL8,SRRM5,SFXN1,STX8,NSDHL,TMX3,IGF1R,EMC2,CCNY,RPL23A,HAPSTR1,PRDX4,MSH6,RIGI,NDUFA2,CCDC47,LBR,NDUFS3,HSPA13,FAM169A,SRP72,SELENOT,GXYLT1,CCNF,GANAB,ZNF622,VIRMA,SEC63,VKORC1L1,CIAO1,NDUFB10,CSK,TUFM,HMOX2,ATP5F1A,RPL26,RPA3,SPCS2,MTDH,SQSTM1,RTN4,RPL4,YKT6,PDHB,TMEM209,EDDM3B,SEC22B,ARHGAP1,RABL3,ST7,UQCRC1,GRM2,HSP90B1,METTL14,TMX4,SLC12A2,LMNA,P3H1,SLC35E3,PDCL,RPL26L1,RPLP0,PHB1,RPL8,RPL9,ATP6V1A,CYB5A,RPLP2,GJA1,WDR44,TMEM237,OS9,DIRAS3,NDUFS8,ERLIN1,EGLN3,PDIA3,CDK5RAP3,RHOG,RPL23,PDAP1,C2CD2L,RB1CC1,TMT1A,SCD5,ERP29,MKLN1,TRIM37,TRIM26,G3BP1,TNF,EMC8,RETREG1,UBE2A,RAF1,MACO1,ERLIN2,FAF2,CYB5R1,CHMP4C,CTSA,EZH2,MOXD1,STIM1,RPN1,CYB5R3,PIGK,ARF1,SEC61B,RPL37A,RMDN3,RPL35,REEP4,RPL19,PRRC2A,B4GAT1,CHCHD3,ABHD12,CUL3,TMED4,RAB11A,VEZT,LMNB1,BRCA1,FAS,VMP1,SCFD1,RPS5,DNAJC3,PMAIP1,NMRAL1,G3BP2,PXMP2,STX7,RNF11,NOTCH2,PGRMC1,AGTRAP,TOR1AIP2,RND2,PRDX3,ARMCX3,LARP4B,VAPB,FKBP10 |
| 6.801e-19 | -41.83 | SPOP (speckle type BTB/POZ protein) | protein interactions | 8405 | 483 | 226 | 19454 | 5460 |
UBE2D1,TRAF6,LYZ,AHSA1,HNRNPD,SLC35D1,RPL23,PSMD3,PRDX1,DPPA2,AGK,RPL7,DHX15,CBFB,PSMB5,KRT8,RPLP2,RBPJ,DCAKD,TPD52,RPL29,NUP153,ACTN4,FAF2,G3BP1,ZBTB16,ETFA,GSTT1,SLC25A5,HSPD1,PCNA,YWHAZ,LMNB1,RPS5,SLC7A11,HSP90AA1,NLRP3,CUL3,RNF40,IRF1,MRPL16,RPS29,EIF4A2,TUBB,RBBP4,SNRPB2,RPL19,SNRPD1,SLC30A7,SOST,MFAP1,H1-5,PRDX3,PPP1CB,CSRP1,G3BP2,ATP2C1,SPOPL,DCTN3,HADHA,CCDC86,NUP50,POR,BRD3,RAB3A,H2AC14,HDAC6,ZMYND11,MAPRE2,MRPS23,SRP14,HRAS,CTDSPL2,LDLR,TOPORS,ILF2,MSRB3,SRP72,CCDC47,AGPAT5,PAK1IP1,CTNNBL1,RPS13,CTNND1,PPP1R12A,RAB1A,FAF1,TCOF1,CACUL1,CHORDC1,HSPA14,ZCCHC12,AR,NONO,KPNA6,TUFM,GMNN,LDHA,TECR,DEK,TUBA1B,ENO1,EIF2AK2,CTNNA1,RTRAF,ACAT1,PTEN,ODR4,TRIM24,UBE2I,CDK1,JUP,HNRNPH3,RBFOX2,RPS14,PCK2,TIMMDC1,UBA52,KDELR2,HACD2,SLC7A1,EIF5B,RPL4,PIAS1,PRPF4,RTN4,SQSTM1,TMEM126B,DDX1,DRG1,IFT25,DIRAS2,YWHAG,YWHAH,RPS10,HNRNPL,FAM98A,MEAF6,PGR,MPDU1,ANXA4,TUBB4B,NDUFA12,RPS23,NUDCD3,RPS7,EEF2,RUVBL1,RPS4X,PRPS1,PABPC1,EWSR1,TRIM21,MYO1B,RTCB,SPCS3,CCT2,GCC1,CHTOP,COP1,RPS26,MYC,HNRNPC,LDHB,EPS8,HMGCS1,BRMS1,ATP5F1B,TIMM21,SMU1,CTBP1,ACAA2,NUFIP2,RPL27A,LAP3,SHMT1,PAFAH1B1,PSMB3,DHRS4,PHB2,EEF1G,DDX39B,TMEM160,XRCC5,HSPA8,SF3B1,DDIT3,DDX5,RPS2,KPNA1,CDK12,RPL10A,GAPDH,FZR1,RPS16,CD274,SSBP1,RPL32,DDX42,ACADSB,CDK4,RPSA,PDE12,NEDD8,HNRNPK,MYD88,DHX9,SPOP,UBE2E3,IGF2BP1,SLC25A1,EGLN2,CDC20,TRAF1,UQCRC2,RPS3,PSMA6,MACROH2A1,GIT2,SUMO1,HCST,RBM22,HSPA5,TMX2,MAIP1,PGK1 |
| 9.785e-19 | -41.47 | regulation of signaling | biological process | GO:0023051 | 3534 | 1258 | 18204 | 5365 |
CSH1,PBLD,IL18,RB1CC1,GTF2H2,PRDX1,LAMTOR3,UQCC2,SCHIP1,BACE1,FASLG,TNFAIP8L1,INSIG2,RNF41,THY1,PIK3CG,NECTIN2,PDE4B,MIR140,F7,PIK3CA,CD47,TIAM1,IL17F,NLE1,PAFAH1B1,NTF4,NLGN1,TCIM,RGS7BP,ICAM1,STAU1,NEO1,P2RY12,LYPD6,ROCK1,PDCD4,MIR15A,ZFAND2B,PIK3R2,CUL3,NR0B1,PIK3R1,SLC6A6,NR2E1,ZNRF1,YWHAZ,OSM,MIR30E,PRKACB,CPLX1,FZD4,NIBAN2,OPRK1,MIR218-1,RXFP2,CCNB1,RPS12,TLR1,BCL9,CARD19,FABP5,PPM1B,FGF23,PRELID1,VEGFA,RGS6,SLC38A2,RALGAPA2,IL23A,PRRT1,MIR874,NF2,LAMTOR2,TIMP1,RNF115,SAMHD1,BFAR,FGF16,SYK,CD40,ARFGEF1,TMBIM6,ACVR1B,TXNDC12,SCG5,HDAC6,ZDHHC17,S100A8,NOG,PRR5L,RGL2,FBXW7,CCAR2,SELENOT,TRIM5,STK11,CREB3,SPTBN1,SCYL2,KCTD10,MIR101-1,ASIC1,TRIM32,LACRT,BIRC2,DUSP1,KBTBD6,EGFL7,CLEC12B,DUSP9,CTNND1,DMPK,CYP1B1,SLC12A2,MIR373,RAB5A,MIR183,TLR2,CSNK1A1L,DIRAS1,VAMP3,PICK1,PPIF,CYRIB,TBK1,SYP,CCL2,DUSP6,NHERF1,NPSR1,MAP2K6,NPPC,WBP2,PDE2A,NUP62,JMJD8,MAPKAPK5,DRD1,PIH1D1,MIR16-1,CHRM3,CACNB4,PSD2,OPRL1,PPP2CB,MIR1224,ERRFI1,FAM89B,AKT3,CA2,IQSEC1,GRAP2,BVES,PRNP,SPRY1,HAX1,DAPK3,OR2AT4,GPR137,TMBIM1,CDC42SE1,ACSL4,ACVR1C,MIR223,DNAJC27,TMEM100,LRRTM1,DDX1,KPNA1,MOSMO,MMP14,ELF1,UBE2K,NDST1,AGPAT1,IL6,MOB3B,EFCAB7,BAX,TRAF3IP2,EIF4E,GNAO1,GADD45G,PADI2,ASPM,PTP4A3,GNAQ,PYDC2,CD86,ACAA2,MMP9,HDAC3,LEPROTL1,PLCB1,TLR9,OCIAD2,SH2D1A,MCL1,SYT4,SEMA4C,NACC2,GRIA2,PPP1R10,CDC73,TNIK,MIR96,TMEM204,MAD2L2,GPR65,NMI,EDNRA,DSTYK,WNT10B,MIR204,CLEC6A,PEX5L,SIPA1L1,SAR1B,CNRIP1,CHMP2B,CD80,LPAR2,UCN,VPS18,OPTN,HHIP,SLC35C1,FAM107A,PPP3CA,HERC4,WNT7A,ARFGAP1,SLC6A1,MIR182,TGFB3,SIAH2,IL1B,AKT1,AGR2,TLR6,TMED4,DUSP26,PFKFB2,GPC1,SLC25A31,RPL26,SGMS1,SPRED1,UCP2,CNOT2,UBE2W,ENY2,LPAR6,NFKBIA,CIBAR1,SAP30,IGF1,SIRT7,CALR,NSG1,TAX1BP3,FBXO9,MIR675,GSTP1,GID8,VDR,MAP1B,BAK1,TXN,RGS5,RBBP4,GH1,TNFAIP3,RETN,OXTR,NPVF,KICS2,INPP5E,MT3,MET,DLK2,MIR320A,XBP1,TSPAN5,PID1,KIT,FAS,PATE4,MIRLET7B,TGFBR2,MIR130A,PAK2,PAIP2,CAAP1,CNR1,AR,UBE2D1,SOD1,TSG101,PPP5C,PIP5K1A,TFG,PPP3R2,PLA2G5,RPGRIP1L,NRP1,PCSK9,FGF1,NR1H2,MIR125A,USP46,GLCE,CPLX2,TMEM88,PRKCE,SYVN1,CDK5RAP3,PARL,MIR10B,RGMA,MIR26B,PCGF2,ARHGAP1,GABBR1,ITGAV,ACKR3,TMEM33,HSPA8,GHR,LARGE1,PTPN1,LAMB2,CRBN,PIP4P1,HOMER1,TMEM14A,ZBED3,DLG4,CER1,RPS15,IFI6,TLR4,APLNR,SEC14L1,JADE1,TNFSF10,MDM2,KCTD12,PPFIA3,SDCBP,TP53,STK4,MIR1-1,AVPI1,SOST,SYNJ2BP,MAP3K3,TNFAIP6,DDX5,NEK7,SOD2,TRIM52,KLHL22,HELLS,CHMP5,HOMER3,SUFU,IRAK4,CAMKV,TNFAIP8L3,PPP2R1A,NREP,MLF1,SLC15A2,MIR212,MIR503,SV2B,SLC16A1,UFL1,FCMR,F10,HINT1,C1QTNF1,S100B,LGALS3,TRIM44,TRIM15,SIAH1,RBCK1,CYP27B1,FAF1,MIR195,MIR198,ATAT1,STUB1,FGF7,CDK5,CTDSPL2,PFDN5,HFE,BCL6,CXCL12,RHOU,HECW1,FBP1,MIR98,TBC1D24,EMILIN1,ARHGAP12,MZB1,CHRDL1,DUSP10,PLG,LURAP1,TNF,TWSG1,FGF3,RBPJ,NDUFAF2,MUL1,GRM8,CX3CL1,BRMS1L,SLC25A4,AVPR1B,TESPA1,SEC13,EDA2R,ING1,PHB1,RPA2,LRRTM2,PDIA3,RUVBL1,MIR214,MIR17,YWHAB,GJA1,CASTOR2,NLRP3,TIFA,IRF4,ARF6,LYNX1,CSNK2B,TBC1D16,CTSD,LSM14A,FOLR1,MDFI,TMSB4X,RNF152,ILK,CASP4,EID2,SLC25A5,NLRP2,NPY5R,GREM2,PTPMT1,RB1,CITED1,GNG7,TBC1D10C,TNFAIP1,GPR89A,CCL3,HNF1B,MIF,YWHAH,RASL10B,FRZB,TPD52L1,RWDD3,SCG2,IL12A,REN,MIR132,BCL10,TEDC2,IRF3,HEY2,MAP3K12,IL6ST,CSF2,BTN2A2,FBXO8,STK3,OPRM1,RNF34,KCNB1,RGS19,CCL5,SPEF1,UBAC2,AKAP12,DYRK2,TLR3,TRIM68,EPHA4,MIR302B,SFRP1,FLCN,IGF1R,CSNK1E,FERMT2,IFT172,DUSP19,SOCS2,NUPR1,CDC42,PPIA,HSPA5,SOCS5,LDLRAD4,HTRA2,OPHN1,TMEM127,CYTH1,BEND6,GADD45B,NPTN,IL4,MYD88,TACR1,IGFBP3,CBLN2,MIR149,FXN,CD46,CD81,MIR146A,TULP3,ATP2C1,CPTP,TYROBP,DOK4,EEF1E1,CSNK1G3,TMEM101,FURIN,MAVS,DEPDC1B,MYORG,MAD2L1BP,SWAP70,CDKN2AIP,RUVBL2,DKK3,ING2,EFNA5,STAMBPL1,LANCL2,ANAPC15,GPR35,COL3A1,GAS8,CA8,FAM20C,GLRX2,SPP1,RABL3,FEM1B,DKK1,VAMP8,CCR7,SETD9,ISG15,SEMA5A,ADRB2,HCFC2,C9orf72,RNF167,HAND2,MIR346,FRRS1L,OSBP,PPFIA2,MAP2K3,DUSP3,RAB29,LTB,SESN3,TRIM8,MIR9-1,JAGN1,OTUD7B,TLE1,SHISA2,PROK1,CSNK2A1,RGN,GHRL,HCST,IL1R2,NDFIP1,CBL,SOX9,STAT2,ANKRD6,RHEB,CBLN1,LTBR,DICER1,FIS1,SNAI2,BECN1,DLG1,CHST11,RAB3A,IGBP1,BANF1,DNAJB9,GRAP,EIF4EBP2,MIR29C,FKBP1A,TLR7,IL5,SLC38A9,PELO,ING5,DHX15,KDM1A,CYTH2,HGS,PRMT2,CCR1,MAP2K1,SYNGR1,SAP30L,IGFBP4,WDR11,NUCKS1,MTMR2,FAIM,KCNJ11,TNFSF12,EXT1,ANGPT1,ADRA1A,SRC,SH3BP4,MIR34C,CDK20,DAG1,PHB2,HEXIM1,LEP,HNRNPK,SQSTM1,ATF4,WIF1,EPS8,TRIM21,DYNLL1,GPR37,RNF146,BIRC5,ARHGAP5,MIR34B,PLCL1,IFNG,TAB2,DOK5,SERINC3,PRKRA,RAB8B,PDCL,LGR4,MIR100,SNCG,AFAP1L2,IRF1,TRIM3,BRMS1,CCDC3,LMO3,NTRK2,MIR296,NTRK3,SHOC2,BPIFB1,CTNNBIP1,NFE2L2,TICAM1,FBXO7,PRMT6,AKR1C2,NCDN,SMARCB1,MECP2,NDC80,IVNS1ABP,BMPR1A,SEMA7A,SLC38A1,ADGRG1,BMPR2,LPXN,UBASH3B,MIR29A,CLU,MIR205,MINAR1,OTULIN,WDR83,CISH,RALB,RPS7,FCGR2B,ATF3,NFKBIL1,NKX3-1,STK38,ADIPOR1,STAP1,SLC7A11,SARM1,LMBR1L,ALKAL1,CD63,DUSP22,KCNJ10,SMAD3,MIR24-1,RAP1A,EIF4A3,PIK3AP1,TMEM108,CRHBP,TAF9,CCN3,SELENOK,DDIT4L,TFRC,GIT2,TRIM62,GSKIP,MIR181D,LAMTOR1,CD2AP,CD38,FKTN,NDP,MIR222,TICAM2,TRAF6,NLGN2,GADD45A,FXR2,CCL19,GRM2,C2CD2L,JPT2,NINJ1,TRIB1,CHI3L1,DISC1,HCLS1,TAFA1,TASL,BMPR1B,SOSTDC1,PML,SYBU,CHN2,CRADD,TERT,SPATA2,NFKB1,GNA11,SRI,KCTD16,IGSF11,TRIM34,PRL,OTX2,MIR186,GRIK1,MIR885,CPLX3,ENO1,LDLR,ADRB1,NEUROD2,MIR449A,MIR10A,GRM1,TMEM196,GPR37L1,GPC4,SLC1A3,PAK5,TRAF7,VEGFC,FLOT1,PPARA,PELI1,PEA15,YWHAG,FOXP1,UBE3A,IL12B,RNF14,LRRC4,FGR,BRAP,MIR185,ABHD6,RSAD2,CSK,STAMBP,USP2,ERP29,UBB,DLGAP4,MIR107,BGLAP,PCDH17,GNAZ,ILDR1,SMURF1,RTN4,EMP2,RGS10,PCK2,HACD3,GLIPR2,UBE2B,PEBP1,NGDN,ELAPOR2,ANAPC2,MSX2,CPNE1,LILRA2,MIR375,HADH,VWF,MIR519D,INHA,CACNG3,MIR30B,MIR21,FGFBP1,SIN3A,RRAGB,VAV2,TTC23,CD36,TPT1,PMAIP1,SNAPIN,MIR210,TCF21,NDUFS3,SYN3,ZNF592,FAM53B,MIR1271,ZMYND11,LMNA,P2RY4,UBE2V1,STARD13,MIOS,NOP53,MIR92B,MIR99A,GABARAP,PRMT5,SELENOS,TANK,GRB10,SMAD4,ARHGAP15,SDHAF2,DRD3,VDAC2,PDCD10,EP300,SNX5,BOK,CTSK,HYAL2,MIR95,SLC1A1,CTNNB1,RALA,GPX1,CYFIP2,TMEM106A,KLK5,HTRA1,GRIA1,AATF,ADRB3,GNAI2,MIR206,CD14,EIF2AK2,MIR221,ARRDC3,CRKL,NCOA5,RRN3,MIR497,TRIM24,UBE2N,DIRAS2,CARTPT,LIMS2,JAK2,PTEN,STXBP1,P2RY10,BCL2L1,TSPAN15,TIRAP,IRAK1BP1,STAT1,TTI2,BST2,MIR573,MIR545,GSK3A,CRY1,DVL2,RAMP3,SSX2IP,FGD2,BAD,UGCG,GRID1,SLC4A8,DEFB114,G0S2,PRDX2,FGFR1,P2RY1,MIR340,ADORA3,ADORA1,FGF22,NKIRAS1,PTPN11,NETO1,DDIT3,LRRC8A,FAM13B,SLC4A10,EYA3,DHRS3,GHITM,NONO,RGS1,DIPK2A,RRAGA,LPAR1,CXCL8,MIR133B,CCNY,FKBP8,SPPL3,CTSC,ARF1,LCMT1,AZI2,CLEC7A,ITGA6,ZNF451,UBE2D3,MIR34A,ARHGAP21,F11R,PDE9A,TSPO,UFD1,RAP2A,TMEM237,ZNHIT1,MIR106A,SESN2,PRKCQ,SLA2,RELL2,GPNMB,JUP,PPARG,CLSTN3,RACGAP1,LIPA,SRARP,RPL23,SFRP4,PAQR3,CCDC22,CSNK1A1,FSTL1,TPBG,EPO,SLC6A4,NR4A2,AP1AR,CNOT7,IKBKB,IL34,TGFB1I1,EGR1,GAPDH,MIRLET7G,PYCR1,NCSTN,RPS20,FZD6,YTHDF2,LEMD3,CHRNB2,EZH2,CHRNA7,OSBPL8,IL7,ABHD17A,MME,CXXC5,YTHDF1,MAPRE2,HMGB1,RGS2,MPIG6B,NTNG2,PTK7,STX1A,CDC42SE2,KLK6,EPHA2,CXCR4,TMEM198,PLEKHF1,CD226,HRAS,MIR23A,PYCARD,MIR361,AGER,RBBP7,FGF17,LBH,CRLF3,ADIPOQ,MAP3K11,DDRGK1,IL10,ROCK2,RAF1,SLC39A10,MIR145,TRAF2,CX3CR1,DBH,MSX1,TRAF1,SNX14,TRIM6,LY96,RPS3,VAMP7,DDR1,CFTR,NEFL,PRKCA,ACVR1,EIF4E2,AIPL1,CCR2,F2,MIRLET7C,GAS2,INA,PIP4K2C,CDH11,CAPN1,RHOH,UFM1,PLSCR1,ATAD1,RPF2,VAMP2,RELL1,PSMD10,INPPL1,ZNF622,HAPSTR1,SPHK2,JPH4,GUCY1B1,FBXW11,NKIRAS2,STRADB,CTTN,ADNP,CGAS,MIR424,LGI1,CYP26A1,PELI3,SNIP1,APLN,ATP6AP2,INPP5K,DDT,HTR2A,USP15,SMAD5,SOCS4,SNAP25,AKIP1,PEG10,G3BP1,CASK,DOK6,PREPL,LRRC14,WWP2,HCRT,DLX1,RIMS3,SOS2,CREB1,MIR126,FRMD8,IER3,MYC,MIR142,ZFAND6,HSPB1,MIR490,CDC20,GPR17,IFNAR1,DAPK1,GFI1,CNKSR3,ZMPSTE24,MIR208A,ARHGAP19,BUD31,BRCA1,SMAD2,MIR421,MIR342,SNX3,FAM83B,MIR324,LILRB4,TNKS2,PSEN1,PPP1R2,EGR2,ARL6IP5,MTM1,TRIM26,PTN,HBEGF,CD4,RNF113A,IFNB1,TRIM11,CAV1,SOCS3,SLC20A1,ACHE,RC3H2,USP8,GPBAR1,HTR1A,TAB1,TNKS,TAX1BP1,CD28,HSP90AB1,FKBP1B,CDKN2D,VGLL4,PIM2,CAV3,MSTN,LYPLAL1,MEF2C,NFKBIB,PDE8A,PTPN22,SOX2,GCLC,DYRK1A,MIR152,CDH13,DDIT4,GREM1,CREBBP,PROX1,CYTH4,ENHO,MTDH,RIMS4,ACTA2,PAK1IP1,MBD5,KRAS,NOTCH2,PAK6,CRYBA1,IL1A,CHP1,TGFB2,GKAP1,FGF10,NCK1,SPRED2,PRCP,MIR20A,CCL21,ARHGAP25,TRIM22,AIP,TNR,CTNNA1,IFI35,ADAMTS20,SLC35F6,LITAF,PICALM,ATP1A2,MAD2L1,H2BC11,NLRP6,IRF7,CHRM1,ATP2B4,MIR200C,MIR708,CAV2,TMEM170B,TMOD2,RIT2,ACTN4,MIR1260B,CHGA,SHC1,PRKCB,PAGR1,CRHR1,RAP1B,OAS1,RNF126,COPS5 |
| 1.011e-18 | -41.44 | RPL7 (ribosomal protein L7) | protein interactions | 6129 | 441 | 210 | 19454 | 5460 |
EMC9,NOP53,G3BP2,BRCA1,RPS5,HSP90AA1,RIT1,HNF1B,CUL2,CUL3,ZNF668,RPS29,RPL35,RPL19,MAD2L2,ZNF22,ARF1,RAN,RPL37A,SEC61B,RPS9,EZH2,NGB,CHMP4C,RPS11,POLR2C,B3GNT2,RAF1,RPL29,OTUD6B,LGR4,TNF,TRIM26,TRIM37,GNL1,TRIP4,SLC25A5,UBE3A,RPS24,WDR12,RPL23,MAP3K14,NOP58,RPL7,HYPK,FOLR1,RPL9,RPL8,PHB1,RPLP2,RPLP1,METTL14,GRM2,H2AC7,RPLP0,RPL26L1,ATG16L1,RPS14,CDK7,RPL4,FBXW7,HMGB1,BRIX1,UTP23,RPA3,SIRT7,MTDH,CDC73,MAPRE1,DNAJC19,RPL26,PPP1CC,DNAJC8,TUFM,NDN,RPL13A,SH3BGRL,RPL22,CCNF,METAP2,EIF4A3,PRKRA,RPS12,PTEN,UBE2I,RPS20,ILF2,SRP72,FBP1,MAP2K3,MAP1LC3B,EEF1A1,RPL15,NOC4L,VRK1,RPS13,SMN1,NKRF,RPL23A,GRSF1,EMC4,HDAC6,RPL35A,CDK9,ZNF7,EFNA3,RPL12,KRR1,ARL10,RCHY1,PPT1,MAP2K1,PIH1D1,RPL27A,MTF1,FBXO42,UFL1,STAU1,MRPS7,NGRN,RPS28,HDAC5,HSPA8,RPS26,NSA2,MYC,THAP7,BTF3,MATR3,USP38,RPL10,MRPL13,TUBB4B,RPL18,RPS23,MAGEB10,DNAJC25,RPS7,MSX2,EEF2,KRAS,RPL28,RPS4X,RPL31,PABPC1,AGR2,DRG1,MAGOH,IFI16,WWP2,RPL6,DDRGK1,RPS10,HSP90AB1,EED,RPA2,DYRK2,HEXIM1,ZNF770,CFTR,RPS15,HSPA5,BAP1,RPL27,PML,RNF113A,SPOP,TRIM23,RC3H2,UBE2H,RPL7A,RPL10L,PSPC1,RPS3,TFCP2,DNAJC2,RNF8,KBTBD4,UBL4A,MTCH2,RPSA,TP53,SRSF12,MEPCE,PSMB10,RPL17,SNIP1,ABCE1,RPL3,TUBG1,SNRNP70,RPL24,RPS2,RPL10A,ENY2,COPS5,CSNK2A1,API5,FZR1,SPPL3,CAND1,RPS16,DNAJC1,RPS27L,RBM42,TMPO,DKC1,SURF6,RPL32,CD4 |
| 1.221e-18 | -41.25 | SF3B1 (splicing factor 3b subunit 1) | protein interactions | 23451 | 537 | 245 | 19454 | 5460 |
SUGP1,SMARCA5,RSPH1,RBM7,UBE2H,ATP1A1,RC3H2,SPOP,MOB4,FGFBP1,ZBTB33,SF3B6,DYRK1A,SMURF1,CFTR,PPP1R8,MIR34B,MIR7-1,TFIP11,MIR21,HEXIM1,ZNF326,RPA2,RNF113A,MIR10B,DDX46,BAP1,MIR107,MIR29A,RBM22,HDAC3,E4F1,COPS5,CSNK2A1,RBM17,USP2,RPS2,NOL12,KPNA1,ARL4D,ALYREF,SSBP1,SURF6,CDC5L,TMPO,MIR429,MIRLET7G,FZR1,CAND1,TMED9,TP53,RPSA,RNF8,NUPR1,SURF4,DDX42,MIR9-3,RPL3,MIR200A,SNIP1,CAPZA1,MIR16-2,MIRLET7C,MEPCE,HNRNPK,KPNA2,SNRNP48,CDC40,H3C1,SNRPB,TTC33,BTF3,HNRNPC,MYC,H1-1,FBXW11,MIRLET7B,SMU1,SF3B4,CMTR1,SCNM1,RPL10,SNRNP40,MATR3,MTF1,TRMT112,PIH1D1,CSNK1A1,DDX5,EP300,HDAC5,HSPA8,SF3B1,SNRPA,DDX39B,SAP18,STAU1,SSR3,TRA2B,SRSF2,HNRNPA0,UFL1,EMC1,DDRGK1,MIR29C,MIR143,WWP2,IFI16,BAZ1B,MAGOH,MIR140,MIR221,SMAD9,MIR31,MIR214,EED,WDR82,SRSF1,SNRPA1,SNRPD3,SUMO2,COMMD6,TRIR,MIR9-1,RPS10,TNPO2,MIR222,H1-3,SMNDC1,EWSR1,MIR206,MIR9-2,RPL31,CCAR1,MIR155,TFPI,KRAS,AR,DNAJC8,RPL26,AP2A1,MIR145,TRIM24,EIF4A3,TUBA1B,MIR16-1,CCNF,DEK,SMAD5,VIRMA,YES1,MIR1-2,SNRPN,TXNL4A,SF3A1,RPLP0,TOX4,LMNA,MIR34C,MIRLET7I,CLK1,FLCN,PRPF4,SIRT7,MIR205,RPA3,UTP23,MIR7-3,FBXW7,HMGB1,MIR34A,MIR25,KRR1,RCHY1,MIR106B,ZBTB2,CWC15,CDK9,MDM2,TOP1,THOC1,SMAD1,MIR200C,MIR15A,CD2BP2,APOBEC3D,MAP1LC3B,PHF23,TOPORS,ILF2,PPP4C,MIR20A,MIR17,EMC2,ZC3H11A,RPL23A,RIGI,SNRPG,THRAP3,LSM4,MCM4,PRPF31,MIR98,CUL3,RIT1,MIR363,YWHAZ,BRCA1,ZCRB1,SNRPD1,SNRPD2,RSRC1,ERH,SNRPB2,RPL19,MIRLET7D,RPL35,TIMM13,H1-5,ARCN1,MFAP1,USP39,MIR106A,PRPF19,MIR1-1,DDX23,SKIC8,MIR141,PHB1,MIR7-2,FOLR1,DHX15,LGR4,E2F4,RAF1,SNRPE,SART3,SF3B5,CHMP4C,EZH2,PPAN,TRIP4,HSPD1,SSRP1,MCM6 |
| 1.298e-18 | -41.19 | regulation of apoptotic process | biological process | GO:0042981 | 1518 | 600 | 18204 | 5365 |
CD2AP,CD38,NAE1,CYP1B1,MIR222,GADD45A,TRAF6,POU3F4,G6PD,VPS54,PIAS1,CCL19,PPIF,SYCE3,CTLA4,CCL2,HCLS1,DUSP6,NHERF1,BMPR1B,MAP2K6,NPPC,NUP62,PML,CRADD,PIH1D1,TERT,MIR16-1,NFKB1,EIF2S1,ARG2,DCUN1D3,BFAR,TMIGD1,NLRP1,CLU,CD40,TMBIM6,SAV1,TXNDC12,RPS7,FCGR2B,S100A8,NOG,ATF3,AKR1B1,NME2,RGL2,FBXW7,NKX3-1,CCAR2,CREB3,SLC7A11,SARM1,IFIT2,SMAD3,MIR101-1,MIR24-1,PDCD1,MAGEA4,GPAM,TAF9,TRIM32,EGLN3,LACRT,BIRC2,TFRC,LAMP3,PTCRA,PIK3R1,NR2E1,YWHAZ,MIR30E,CTNNBL1,BRMS1,DNAJC5,CAPN2,DDAH2,NTRK2,AREL1,NIBAN2,NDUFAF4,RXFP2,EIF2B5,NFE2L2,MIR137,FBXO7,HIGD2A,HSPB6,MECP2,IVNS1ABP,SIGMAR1,VSTM2L,MIR181C,PRELID1,BMPR1A,VEGFA,CD248,CCAR1,NF2,BNIP3L,MIR29A,TIMP1,FAM162A,NME1,RB1CC1,FAIM,TNFSF12,PNMA1,ANGPT1,TRIM35,PPID,SRC,BACE1,PHB2,HNRNPK,FASLG,LEP,TNFAIP8L1,SQSTM1,CD40LG,PIK3CG,ATF4,KRIT1,MIR140,PIK3CA,BIRC5,NTF4,IFNG,APEX1,TCIM,ICAM1,SERINC3,PRKRA,PDCD4,ROCK1,MIR15A,HTRA1,MIR320A,XBP1,AATF,ANP32B,GNAI2,MTRNR2L3,MLLT11,FAS,EIF2AK2,STK26,MIRLET7B,IL2,MIR221,PAK2,UBE2M,PSMG2,TSC22D3,CCND1,CAAP1,CNR1,RRN3,AR,TRIM24,SOD1,JAK2,LIMS2,STXBP1,MORF4L1,BCL2L1,LRP6,NRP1,PCSK9,STAT1,MIR125A,B4GALT1,EGLN2,TEX261,SYVN1,AKR1A1,PARL,DEDD,BAD,G0S2,WNT7A,MIR182,ZMYND11,CALHM2,LMNA,TGFB3,SIAH2,IL1B,NDNF,NOP53,AIFM1,AKT1,TLR6,SELENOS,SMAD4,SLC25A31,RPL26,SGMS1,UCP2,PDCD10,VDAC2,CERS6,PTRH2,IGF1,CALR,BOK,NAA16,MIR675,PIK3R3,CTSK,HYAL2,GSTP1,VDR,BAK1,SLC1A1,CTNNB1,TNFAIP3,PNMA5,GPX1,MT3,HDAC3,RTN4,TNFRSF1B,DNM2,ATG7,RPL10,MCL1,TIA1,UBE2B,RGCC,GPRASP3,ZBTB16,MYBL2,MAEA,DNAJB6,SFN,MSX2,NACC2,MIR375,PPP1R10,DNAJC3,CDC73,MIR21,MIR30B,SIN3A,TXNIP,DSTYK,WNT10B,MIR204,BCL2A1,SERPINB9,TPT1,ANXA4,UCN,PMAIP1,MIR210,CASP12,HHIP,NDUFS3,HYPK,JUN,ACTL6A,RNF122,MIR186,DMAP1,VDAC1,CD274,ENO1,HSPD1,MIR449A,CLIP3,PRNP,TMEM196,HAX1,DAPK3,PAK5,TRAF7,TMBIM1,PPARA,ACVR1C,PEA15,NKX3-2,FOXP1,KPNA1,IL12B,IL6,BAX,STAMBP,ERP29,TP53INP1,GADD45G,UBB,RTKN,ACAA2,BTG1,MMP9,MIR17,RNF144B,NEFL,PRKCA,ACVR1,AIPL1,FOXC2,SLC25A27,ALDH1A3,UFM1,MIEN1,CTSD,CFDP1,CXCL10,PSMD10,ZNF622,CIDEB,CDKN1A,RBM5,HSP90B1,SPHK2,RAG1,CASP4,ASIC2,NPY5R,OGG1,SLC25A5,STRADB,PTPMT1,CTTN,RB1,ADNP,CITED1,DFFA,STUB1,HMGB1,MIR495,ORMDL3,CDK5,KCNMA1,PNMA2,PLAC8,BCL6,PNMA3,CXCL12,MIR98,EMILIN1,PLEKHF1,RHOB,PYCARD,HRAS,MIR23A,ZNF304,MIR361,NAA15,ADIPOQ,TNF,ACTB,MAP3K11,DDRGK1,PTGFR,IL10,PPT1,RAF1,SLC39A10,CX3CL1,TRAF2,MIR145,CX3CR1,DBH,MSX1,SLC25A4,ANP32A,TRAF1,RPS3,PHB1,PDIA3,RUVBL1,CD3G,CDKN1B,BTG2,TSPO,HELLS,NQO1,TNFAIP8L3,PPP2R1A,TNFAIP8L2,NAA35,PRKCQ,RETREG1,PPARG,UFL1,FCMR,SFRP4,FATE1,FSTL1,EPO,MNAT1,RAD21,MIR28,NR4A2,LGALS3,CLN8,SIAH1,RBCK1,EGR1,PYCR1,FAF1,MIR195,MIR198,MTRNR2L7,IL7,MIR26B,SAP18,PCGF2,MGMT,PRDX2,FGFR1,ITGAV,ACKR3,HSPA8,CSRNP3,ADORA1,PTPN1,MIR590,TOMM70,TMEM14A,SMG9,KLF4,DDIT3,EYA3,IFI6,TLR4,GHITM,TFPT,ARF4,NONO,DIPK2A,LPAR1,TNFSF10,MDM2,API5,FKBP8,MAEL,CTSC,TP53,ST6GAL1,ERCC3,STK4,LCMT1,IDO1,MIR1-1,MITF,VPS72,ITGA6,IL13,MIR34A,SOD2,CSNK2A1,MIR20A,RGN,GHRL,CCL21,CBL,SOX9,CCR5,FZD3,CTNNA1,BAG3,LTBR,FIS1,SNAI2,BECN1,ADAMTS20,CHST11,IGBP1,SLC35F6,MAD2L1,MIR29C,IRF7,ING5,CTSB,KDM1A,ACTN4,PRMT2,SHC1,IRF8,LTA,TWIST2,COPS5,SOX2,CEACAM5,GCLC,FEM1B,SDF2L1,DKK1,CCR7,SEMA5A,GREM1,TNFSF18,MTDH,HAND2,PDE1A,PLSCR3,DPEP1,SRPK2,KRAS,NOTCH2,CRYBA1,IL1A,TGFB2,LTB,FGF10,NCK1,TLE1,HSPA5,HTRA2,GADD45B,BRCA1,IL4,IFT57,IGFBP3,FXN,MIR146A,PSEN1,ARL6IP5,IFNB1,CAV1,SOCS3,EEF1E1,MEAF6,PTPRZ1,TAX1BP1,CD28,HSP90AB1,AGAP2,PIM2,CDKN2D,RUVBL2,TNFAIP8,ING2,MEF2C,ST3GAL1,CCL3,HNF1B,MIF,PDCD5,FRZB,LILRB1,TPD52L1,CNTFR,PELI3,CDK1,SCG2,IL12A,BCL10,MIR132,HTR2A,HSP90AA1,HEY2,MAP3K12,IRF3,USP15,IL6ST,CSF2,SMAD5,CFL1,STK3,DAD1,MTCH2,RNF34,CDK5R1,KCNB1,CCL5,MIR106B,DLX1,AKAP12,GBE1,IL2RB,GLO1,DDX42,TLR3,MIR200A,SFRP1,FLCN,CREB1,MIR126,IGF1R,IER3,SNCB,FBXO11,MYC,MIR142,SOCS2,ZFAND6,CRYAB,HSPB1,NUPR1,PRDX3,CDC42,DAPK1,PPIA,HSPB2 |
| 1.331e-18 | -41.16 | FANCD2 (FA complementation group D2) | protein interactions | 2177 | 792 | 335 | 19454 | 5460 |
RFC5,MCM3,MCM4,OPRM1,GPR17,RAB11A,CUL3,RPS5,HSP90AA1,RMI1,YWHAZ,BRCA1,LMNB1,SNRPD1,SNRPD2,RPS9,CPSF1,PARP2,RAN,CHCHD3,SNRPB2,ERH,RPL19,ACTB,RBBP4,RPL35,ACTL6A,H1-5,IRF2BPL,MYL6,USP39,VAPB,ADNP,H2AC1,CCDC86,PSMC1,CDSN,AZGP1,NPTN,HNRNPA1,P2RY10,PDIA3,PRPF19,HMGA1,PRDX1,STOML2,FAM174A,LYZ,HNRNPD,RPL23,DDX23,CSTA,HBA1,RPLP2,HP1BP3,RPL9,FOLR1,RPL8,THOC2,PHB1,ERLIN1,CNTROB,PPIA,DHX15,NOP58,SPTAN1,CCAR2,RPL7,ACTN4,RPL29,ERLIN2,RAF1,RPS11,POLR2C,RPN1,NME1,AQP3,PCNA,JRKL,RPS24,BAG2,SLC25A5,HSPD1,HNRNPA2B1,MCM6,RAD21,RFC2,FANCG,FLOT1,RFC3,G3BP1,LAMB2,RBBP7,CDK20,RPL26,ATP5F1A,RUNX1,NONO,TUFM,CTSD,EPHA2,GANAB,RPS12,RPS20,PELP1,CCNF,EIF4A3,TNFRSF1B,ENO1,UBB,SH3BGRL,RPL22,GNAI2,JUNB,MAGOHB,RAB14,TXN,LDHA,RPL13A,UQCRC1,RPS14,SF3A1,TPT1,CCND1,RPLP0,HNRNPH3,JUP,LMNA,STOM,HSP90B1,H2AC7,VIPR1,H2BC12,ARPC2,RPA3,PIAS1,BRIX1,PDHB,NF2,IRF7,GTF2I,SMC4,FBXW7,RPL4,H2AC14,STYK1,TOPBP1,TNKS,SRP14,HACD3,RPL12,KRR1,CAV1,RPL35A,TOP1,DDX39A,GGCT,RPL15,COMTD1,ILF2,SERPINA1,ACTR2,RPL23A,ZC3H11A,EMC2,IGF1R,SEMG2,RAB1A,GLUL,TCOF1,RPS13,H2AC6,MDC1,THRAP3,TF,NSMCE3,RMI2,PSMD1,SNRPB,MYC,LDHB,HNRNPC,SFN,HNRNPAB,RPS26,SERPINH1,RBBP8,CHTOP,PSMD14,H1-10,H2AZ2,SMU1,LMBR1L,S1PR4,VDAC2,DLST,APLNR,LRIF1,POLR2B,ATP5F1B,TAGLN2,MATR3,TRIM29,NCOA5,CTBP1,HSPA8,SF3B1,DDX5,LCN1,SNRPA,RFC4,CD40,DDX39B,XRCC5,GNB4,SAP18,HNRNPA0,NDUFS2,PHB2,STAU1,EEF1G,SSR3,YWHAG,PPIB,DDX50,BAZ1B,RPL6,POU5F1,MAGOH,YWHAB,HSPB1,S100A8,CORO1C,FAAP100,SERPINC1,FABP5,FUBP3,ELK1,HMG20A,HSP90AB1,RAB1B,RPS10,HNRNPL,SNRPD3,LYAR,SUMO2,SERPINA3,RPS7,EEF2,MTA2,RPL18,RPS23,PLS3,TUBB4B,CA14,EFNB1,RUVBL2,PDIA6,RPL31,TOP2B,RBM3,PABPC1,CCAR1,RPL28,RPS4X,HNRNPDL,HNRNPF,DCP2,VDAC1,RUVBL1,HMGN4,CFL1,RPS17,SMARCA5,AKT1,RPF2,RPL7A,PSMC5,CALML5,MACROH2A1,PTPMT1,UQCRC2,RPS3,SF3B6,PYGM,CDC42,SPTBN1,SUMO1,H2BC11,RPA2,HBB,ZNF326,SSR1,PGK1,RPL27,NBN,PML,CLU,HSPA5,KDM1A,HP,GAPDH,API5,USP2,RPS2,KPNA1,RPL10A,H2AC4,RPL24,SMCHD1,RAP1B,RAC2,SYNCRIP,ALYREF,COX4I1,RPL32,TMPO,DKC1,ILVBL,CDC5L,FZR1,RPS16,MGARP,H2AX,APOO,MTCH2,RPSA,CBX3,CAPZA2,RPL3,DHX9,RPL17,H3C1,RPIA,HNRNPK |
| 1.446e-18 | -41.08 | USP14 (ubiquitin specific peptidase 14) | protein interactions | 9097 | 461 | 217 | 19454 | 5460 |
MYO6,TAFAZZIN,NLRP3,PFDN2,CDC123,RPL35,ACTB,CHP1,GNB1,PELO,RAN,GNG12,RPS9,PSMB7,ARCN1,RADX,CNTN1,UNC45A,G3BP2,RNF11,PSMC1,ATP5MK,CXCR4,PSMA3,CCDC86,TXNL1,TRAF6,PSMD10,WDR12,RPL23,BCL2L1,HNRNPD,PSMD3,SPTAN1,DHX15,PSMB4,PSMB5,HP1BP3,RPLP1,RPLP2,NME1,E2F4,ACTN4,G3BP1,SSRP1,SAR1B,PSMD12,RPS27A,SRSF4,HSPD1,UBE3A,RPS24,SRSF7,CCDC22,HSPA14,PPP1CC,USP14,GMPS,AR,RPL13A,TMOD3,LDHA,TXN,DEK,RPL22,UBB,CCNF,RPS20,CMBL,CDK1,LMNA,RARS1,TMOD1,TPT1,PSMC4,RPS14,RPL4,NUCKS1,GTF2I,EIF5B,PDHB,GABARAP,RPA3,MTDH,ARPC2,SQSTM1,PSMD7,DNAJC7,ATP5MG,TOP1,MDM2,RPL12,HACD3,H2AZ1,PSMB1,LDLR,SRP72,RAD23B,YTHDF2,CCT5,DDX39A,MAP1LC3B,FARSA,TOM1,VRK1,SEM1,MDC1,RIGI,IL6,SNAP23,PSMD14,CCT2,MCAT,LDHB,PSMA4,MYC,CREBBP,PSMD1,PSMD6,SNRNP40,PSMD4,PSMB6,CBX5,EFHD2,NFKBIA,LMBR1L,CNDP2,PSMB3,EFHD1,RPL27A,GABBR1,HNRNPA0,GNB4,XRCC5,SPECC1L,DDX5,HSPA8,AGR2,H2BC17,HSPB1,RPL6,XPO1,EIF2S1,HNRNPL,RPS10,WDR82,PLS3,TUBB4B,RPS23,RPL18,H1-3,ISG15,HMGN4,PSMA2,PSMA1,RPS4X,CCT8,RBM3,GNA11,TRIM11,MYO1B,IGF2BP1,CCNB1,PSMB2,CFL2,CFL1,ADRM1,RALA,PSMA6,RPS3,SGTA,MACROH2A1,MRPS28,PSMC5,EIF2S2,IDH2,RPA2,UBE2M,SPTBN1,PAAF1,BCL6,MARS1,BANF1,ARFIP1,GFM1,DERL1,SMCHD1,RPL24,BECN1,CCDC92,USP15,MAP4,GAPDH,COPS5,TMPO,UBE2N,SYNCRIP,CAPZA2,ARPC3,CBX3,PSMC3,TAB2,SH3GLB1,MTCH2,ZMYM3,H2AX,TMEM33,KPNA2,TOLLIP,HNRNPK,SRPRB,PSMA5,RPL17,CAPZA1,SLC25A11,MAP1B,DHX9 |
| 1.473e-18 | -41.06 | C1QBP (complement C1q binding protein) | protein interactions | 708 | 778 | 330 | 19454 | 5460 |
DNAJB6,H1-1,MRPS25,CHTOP,BTF3,OSM,COX6B1,MYC,HNRNPAB,RPL10,ESR2,ATP5F1B,TRIM29,PRMT5,MIRLET7B,MRPL13,TACO1,DLST,PIH1D1,MRPS18A,MMP14,NDUFAF3,MRPL12,RPL27A,MRPS7,UFL1,NDUFS2,FXR2,OXCT1,PHB2,ADRB2,HSPA8,HDAC5,EP300,NGRN,BOLA3,ARG2,XRCC5,MIR221,YWHAB,ARMC8,MIR140,MIR31,MRPL9,NDUFV2,MIR29C,YWHAH,YWHAG,ETFRF1,CTNNB1,ACP6,DDRGK1,IFI16,DDX50,WWP2,MIR143,ADCK1,HNRNPL,LYRM2,MIR9-1,MAGED2,MIR214,SRSF1,NDUFA12,FAM136A,RPS23,RPL18,NUDT19,PDHA1,MIR222,SOX2,DNAJC25,ISG15,TUBA1A,TOP3B,HEXA,PRSS35,ETFB,MAGEB10,RPL28,HNRNPDL,HNRNPF,CHCHD2,PSMA1,KGD4,MIR155,MIR206,PDIA6,LSM14A,MIR9-2,PDCD4,OAT,UBE2H,MRPS16,RC3H2,CHCHD4,NDUFAF2,RNASEH1,MRPS28,PTPMT1,UQCRC2,HEXIM1,PRKCA,MIR21,GSTP1,MIR7-1,LUC7L3,QRSL1,MRPL10,H2AB1,GABRA1,CDC42,NDUFAB1,CFTR,MIR34B,GRPEL1,MIR29A,MIR107,NME4,MRPL41,MRPL40,TWNK,RNF113A,DLAT,GFM1,MIR10B,MAIP1,BAP1,RPS2,TRMT5,SNRNP70,SAT2,COPS5,E4F1,LYPLAL1,COX5A,MIR429,CAND1,FZR1,MIRLET7G,RAC2,MRPS9,CD274,SDHB,RPL32,MGME1,COQ10B,COX4I1,ALYREF,SLC25A24,NUPR1,ACADSB,HADH,METTL15,UBL4A,ATP5PB,MRPL47,MEPCE,MIRLET7C,RPL17,MIR16-2,NEDD8,H3C1,PDE12,MRPS33,NUP107,LRP3,HNRNPK,MRPS18B,SNIP1,MIR200A,MRPL52,ATP5PF,MIR363,RPS5,LSM14B,HTRA2,FYTTD1,FAS,LMNB1,NOA1,MRPL16,MIR98,TOMM40,MCM4,FMC1,PYCR1,CUL3,CUL2,MIRLET7D,PRRC2A,NDUFAF4,ERH,MRPL23,ACTB,SNRPD1,RPS9,FAU,NDUFA5,ATP5PO,ARMCX3,PRDX3,SOX21,COIL,TNFSF12,MIR106A,CMAS,HSCB,NOP53,ATP5IF1,CRY1,HADHA,HNRNPD,MIR1-1,MRPS26,PPM1K,MRPL18,HMGA1,CLPX,STOML2,MRPS35,NDUFS8,GATD3,CYB5A,MIR141,RPL8,CBFB,MIR7-2,PHB1,CHMP4C,NDUFS6,NUP153,PPP2R1A,ANP32A,HSDL2,MCM6,MRPS17,IMMP2L,RAD21,AHCYL1,ARL5B,ETFA,GNL1,ATP5F1D,OPA3,HINT2,RPS24,MRPS11,COX8A,HSPD1,PREPL,NDUFA4,DNAJC19,MIR145,PPTC7,ATP5F1A,TUFM,DNAJC8,CDC16,PYCR2,VIRMA,ACAT1,GAB1,CCNF,MRPL53,MIR16-1,MTRES1,LMNA,MRPS34,JUP,PAK5,GRM2,METTL14,MIR1-2,CDK7,ST7,COQ8B,RPS14,NFYB,POLDIP2,MRPL20,MRPL17,MIR7-3,FBXW7,HMGB1,MIRLET7I,MIR34C,DVL2,IDH3A,MIR205,MIR34A,GRSF1,ATP5MG,AKAP17A,ATP5PD,MRPS23,MRPL24,KLF1,DCUN1D1,MRPL50,MIR25,MIR106B,PTPN1,MRPL49,MRPL51,MIR17,MIR20A,NDUFS3,LBR,DDX39A,AURKAIP1,PPIF,MIR200C,MIR15A,RPL15,BCS1L,FBP1,NDUFA2,JPH4,MRPS18C,FASTKD5,MRPL22,ABHD10,HUWE1,HSPE1,DNAJC30,THRAP3,RPL23A,HSD17B10,TFPT |
| 1.748e-18 | -40.89 | RAB7A (RAB7A, member RAS oncogene family) | protein interactions | 7879 | 860 | 358 | 19454 | 5460 |
DIRAS3,NUP35,MAP1LC3A,SNX17,ATP6V1A,CDK5RAP3,PIK3R1,VPS26A,SAR1B,FLOT1,SEMA4C,SCD5,STX12,RPN1,RIMOC1,GDI2,NDUFS6,PPP2R1A,FAF2,ERLIN2,MACO1,RAF1,ACTB,LGALS3,REEP4,LAMTOR3,TUBB,SEC61B,GPR89A,SCFD1,VMP1,RHOB,RAB11A,STX7,PXMP2,ATP6V1G1,UCHL3,RABAC1,PRKD3,EXD2,SLC25A3,KCTD12,VAPB,VPS18,ARMCX3,RRAGA,TOR1AIP2,NOTCH2,ANKRD46,CGAS,HRAS,PTPN1,OSBPL8,POR,RAB22A,LAMP3,KXD1,ATP5MG,LAMTOR2,RIGI,VPS16,RNF115,GNG5,RAB1A,SFXN1,RNF167,VAC14,RNF121,DHRS7B,UBE2V1,UQCRQ,VIRMA,TMOD3,NREP,RHOJ,CCNF,NRP1,SMAD2,GGCX,HMOX2,CHMP2B,TMUB1,YKT6,PIK3R2,RTN4,RHOU,RPA3,DCTN4,CHMP1A,SLC12A2,GOLGA5,STOM,SLC35E1,UQCRC1,ST7,RABL3,SYNGR2,PDE8A,SEC22B,CHMP2A,HNRNPL,PEX13,RAB1B,STX5,RAB35,NDUFV2,DDRGK1,LAMP2,RAB5C,SLC35A2,VAMP8,RAB8B,PDHA1,SNAPIN,DNAJC25,SPG21,TAX1BP1,VDAC2,DLST,FIS1,OAZ1,ATG3,FBXW11,BAG3,SLC30A5,MYC,ITGAV,GOSR1,PHB2,GPHN,TMEM106B,MAP2K1,SEC62,BORCS6,LAP3,TOMM22,BET1,STX6,SLC38A2,LMAN1,VTI1B,RAP1B,SLC39A10,RAC2,ITGA6,ACSL4,DHRS7,LPCAT3,AKAP12,RHBDD3,HNRNPK,RAB3B,CYBRD1,FURIN,CBX3,TP53,TXNDC12,CHMP5,UQCRC2,NECTIN2,ABCG2,SNX14,CISD1,CFL1,GORASP2,DNAJC5,RAB2A,ARFIP1,DERL1,BAP1,TEX264,RAB29,LEMD3,FGFR1,CDC42,ERLIN1,RAB11B,SNX2,SNX1,NEO1,TSG101,WDR6,OCIAD2,PHB1,RHOG,ATG7,FIG4,STOML2,RETREG1,EMC8,BLOC1S2,VPS26B,TMT1A,STIM1,VPS33A,EZH2,VAMP2,CYB5R1,YIPF3,TPD52,MAD2L1,CHCHD3,CHP1,RMDN3,SLC30A7,AP2M1,CYB5R3,PIGK,TOMM40,RHEB,AK3,NDUFB7,VEZT,GPC1,HADHA,BET1L,PMAIP1,NUP50,ATP5MK,ATP5PO,PRDX3,RND2,OTULINL,RAB6A,CAV1,ARF6,HSD17B11,CDCA3,SEC23A,SRPRA,ESYT1,RAB23,EMC4,CTNND1,TOM1,EMC2,PC,SNAP23,STX8,SLC25A20,CTDSP2,SLC29A1,EEF1A1,LBR,MAP1LC3B,CCDC47,VKORC1L1,SH3BP4,SEC63,RAB14,SNX3,WDR45,CHCHD6,ACAT1,PTEN,OPTN,VAMP3,EPHA2,TMEM106C,LGALS8,ATP5F1A,CTSD,RETSAT,TMEM209,FLCN,MAVS,SQSTM1,MTDH,FADS2,LMNA,JUP,HSP90B1,VAMP7,RHOH,EED,CORO1C,ANKRD50,NDUFB8,AGR2,PPFIBP1,TBC1D5,KRAS,NUP42,VDAC1,EFNB1,COA4,RABGGTB,TMEM87A,RINT1,TAPT1,RND3,GLE1,KDELR1,RAB4A,SOX2,NETO2,STBD1,ARFGEF1,ATP6AP2,ATP5F1B,FAM83B,ICAM1,LAMTOR1,GCC1,OST4,TMEM38B,EIF1B,EMC1,HSPA8,COX17,RAB5A,AKAP1,UBAC2,YIPF5,CLDN4,GOSR2,TMPO,MIOS,DNAJC1,ARL6IP5,VPS26C,RGP1,SDHB,COQ8A,CD274,CAMLG,NDUFB4,B9D1,COPS5,ADIPOR2,EDEM1,FKBP8,SRPRB,STX18,RAB13,TFRC,GPD2,MECR,PREB,UBL4A,RAP1A,MTCH2,SLC1A1,STX10,TSSK1B,ATL1,SNX5,C9orf72,VPS39,TOMM20,HSPA5,RAB9A,SNX11,RPA2,VIPAS39,BORCS5,USE1,SAMM50 |
| 1.860e-18 | -40.83 | mRNA binding | molecular function | GO:0003729 | 639 | 294 | 18094 | 5411 |
MIR330,FXR2,GRSF1,DDX4,MIR198,MIR100,RPS5,RC3H2,SHMT1,MIR424,MIR345,RPS26,LSM14B,RBMS2,NKAP,MIR125A,RPS2,MIR339,MIR223,MIR105-1,TSN,MIR573,MIR30A,MYEF2,MIR551A,MIR1260B,MIR148B,MIR214,MIR10A,MIR505,MRPS7,LUC7L3,MIR34A,THOC2,MIR96,MIR30D,HNRNPA0,MECP2,MIR1277,MIR145,RBM38,MIR181C,SF3B6,MIR185,AUH,MIR34B,EIF4E,PPP1R8,MIR497,CELF6,TP53,RPL24,NUDT16,MIR98,MIR1298,SF3B1,MIR30E,MIR548C,MIR298,CDC40,MIR99A,MIR31,RPS13,MIR17,MIR140,METTL14,CHTOP,MIR885,CIRBP,BOLL,MIR136,G3BP2,MIR454,MIR346,MIR874,MIR490,MIR302B,EIF4E2,SNRNP70,MIR1-1,PEG10,MIR23A,SRSF1,MIR9-1,MIR148A,MRPL12,RBM15B,MIR208A,PABPC1,MIR191,ETF1,MIR101-1,EIF3D,HNRNPA2B1,MIR491,MIR661,EXOSC8,MIR10B,RPL13A,MIR183,MIR147A,HSP90AA1,RPL26,MIR222,MIR340,SUPT5H,MIR335,CRYZ,ACO1,MIR572,MIR208B,MIR552,MIR511,MIR142,MIR182,MIR146A,MIRLET7C,YTHDF1,NOVA1,MIR492,PCBP4,HNRNPK,MIRLET7B,MIR301A,MIR106A,MRPL13,MIR342,MIR143,MIR590,TACO1,MIR141,MIR363,MIR137,FUBP3,SECISBP2L,G3BP1,HNRNPC,RPL7,MIR493,MIR149,MIR296,MIR455,RNF20,MIR429,MIR21,NCBP2,CSTF2T,MIR320A,TRA2B,MIR215,DXO,MIR383,MIR155,MIR33B,MIR126,MIR378A,MIR338,PIWIL2,IGF2BP1,MIR373,MIR26B,PAIP2,XPO5,ELAVL4,HNRNPAB,RBFOX3,MIR187,MIR425,EIF2S2,MIR210,SYNCRIP,MIR939,POLDIP3,MIR218-1,RPL35,MIR150,RPS14,MIR29A,CPEB1,MIR24-1,DDX5,CALR,MIR877,UPF3B,MIR193A,LARP4B,MIR188,EDC3,SNIP1,MIR448,MIR130A,MIR769,MIR20A,MIR28,SRSF4,MIR194-1,CCT5,MIR301B,MIR30B,MIR144,MIR181D,MIR204,MIR876,TYMS,DHX9,HNRNPA1,MIR657,MIR625,ALYREF,MIR195,EIF4A3,LSM14A,RPS7,MIR374A,EXOSC4,RPS3,MIR34C,MIR25,MIR132,MIR221,RNF40,MIR106B,TDRD7,MIR133B,MIR190B,MIR92B,CPSF1,MIR186,MIR206,STAU1,DDX39B,RBFOX2,MIR384,MIR212,DDX39A,MIR503,MIR379,FYTTD1,MIR15A,CSTF3,MIR153-1,MIR638,RBM42,MIR640,MIR192,MIR423,MIR139,MIRLET7G,MIR211,MIR708,MIR361,MIR129-1,MIR152,MIR639,RBM5,MIR920,SLPI,MIR32,MIR99B,HNRNPD,MIR16-1,CASC3,HNRNPL,MIR488,MIR3173,MIR519D,MIR449A,SRSF7,MIRLET7I,TIA1,PABPC5,MIR200A,LSM8,MIR495,DDX23,MIR107,IREB2,MIR200C,MIR29C,MIR130B,MIR193B,MIR675,PIWIL1,PABPC1L,YTHDF2,UTP23,MIR135B,DDX50,MIR1224,ELAVL2,CARHSP1,MIR205,MIR1271,MIR873 |
| 1.903e-18 | -40.80 | PMAIP1 (phorbol-12-myristate-13-acetate-induced protein 1) | protein interactions | 5366 | 181 | 107 | 19454 | 5460 |
SEC22B,CNP,SNRNP27,CDC42,UBE2F,SLC12A2,JUP,RAB9A,SQSTM1,PRDX6,EIF5B,SLC7A1,BCL2A1,BNIP3L,RAB2A,DNAJC8,DNAJC5,MTPN,RAP2C,ATP1B3,UBE2H,ATP1A1,VAMP3,STUB1,PITPNB,PSMC5,RALA,ZBTB17,RAB14,GNAI2,RAP1A,TFRC,GNAI3,ATP2B4,SFXN1,SNAP23,SLC16A1,ERO1A,KPNA2,CSE1L,SRPRB,NEDD8,HUWE1,PRDX4,ARF4,COX5A,ATP1B1,ESYT1,DNAJC7,COX4I1,UBE2N,STT3A,HACD3,MCL1,TMED9,LMAN1,PGRMC1,AGTRAP,RAB6A,RNF7,FKBP1A,PEBP1,RAB5A,GNA14,COX17,RP2,ATP6V1G1,STX7,RAB11A,MYC,SLC1A3,BTF3,MDH1,ZMPSTE24,BAX,BAD,GNG12,RRAS2,APEX1,GNB1,ERLIN2,GDI2,STMN2,STX12,ZRANB2,PDIA6,ETFA,HMGN4,ZBTB16,KRAS,ANP32B,RAB5C,STOML2,BTF3L4,UBE2D1,AK2,BCL2L1,TMEM30A,MED4,DDT,PHB1,RAB35,HYPK,SNX2,RAB1B,VAMP7,ZNF593 |
| 1.918e-18 | -40.80 | CHMP4C (charged multivesicular body protein 4C) | protein interactions | 92421 | 676 | 294 | 19454 | 5460 |
SERPINH1,THOC6,FTSJ3,H2AZ2,CIRBP,SNRPB,BAG3,HNRNPC,LDHB,PSMA4,HNRNPAB,SFN,RPL10,CBX5,TAGLN2,MATR3,EFHD2,VDAC2,EIF4B,SHMT1,RPL27A,SAP18,SSR3,EIF1B,TRA2B,DDX5,SF3B1,XRCC5,SPECC1L,RPS28,SNRPA,SLU7,MAGOH,YWHAB,FKBP4,YWHAG,XPO1,RPL6,RAB5C,DDX50,IFI16,BAZ1B,CHMP2A,HSP90AB1,LYAR,SNRPA1,SNRPD3,RPS10,HNRNPL,EIF2S1,MAGED2,CORO1C,RPL18,LIMD2,RPS23,PDHA1,EEF2,H1-3,PRPS1,HNRNPDL,RPL28,RPS4X,VDAC1,HNRNPF,ACTR1B,TRIM11,PDIA6,RTCB,RUVBL2,ABCF1,TOP2B,PABPC1,RPL31,CALU,ABCG2,IGF2BP1,CFL1,RPS17,GSTK1,RPL7A,SMARCA5,MAT2A,PSMB2,RPF2,BUB3,MRPS21,MACROH2A1,CALML5,PSMA6,HS3ST5,SF3B6,DDX4,CSNK1A1L,SNRNP27,SPTBN1,CLU,MARS1,RPS15,WDR3,PRDX6,PGK1,HNRNPH2,BANF1,RPL27,AGPAT1,RPL10A,RPL24,SNRNP70,GAPDH,PGAM1,RIT2,KARS1,CDC5L,TMPO,LMAN1,DKC1,RPS27L,NKAP,ABHD8,RPS16,AKR1B1,UBE2N,RPL32,COMT,EEF1B2,SYNCRIP,SSBP1,BIRC5,ARPC3,CBX3,TFRC,H2AX,RAP1A,IMP3,STRBP,CAPZA1,RPL17,HNRNPK,CSE1L,KPNA2,CHMP1B,RPL3,PALM2AKAP2,RPS5,CCDC25,HSP90AA1,YWHAZ,LMNB1,MCM3,SAMHD1,CFAP20,RPL19,CHCHD3,LGALS3,RPL35,RPL7L1,PRDX2,EIF4A2,RPS9,SNRPD1,RPL37A,RAN,EIF3K,CYB5R3,FAU,ARF1,S100A6,SLC25A3,MYL6,PRDX3,MTX2,H1-5,ACTL6A,SKP1,CSRP1,CCDC86,RPL23,STX1A,VPS4A,DDX23,WDR12,ACTL6B,TRA2A,STOML2,PRPF19,PDIA3,PSMD3,PRDX1,DHX15,CACYBP,NTMT1,SRSF10,RPL7,SPTAN1,LCA5L,NOP58,RPLP1,MRTO4,RPL9,RPL8,SNRPE,RPS11,POLR2C,CHMP4C,GDI2,NME1,RPN1,RPL29,PPP2R1A,ACTN4,FEN1,RAD21,SSRP1,RPS27A,SRSF4,S100A10,EMC8,G3BP1,RPS24,BAG2,ERP29,SCYL2,PPIG,CHORDC1,GMPS,RACGAP1,TUFM,RPL26,CSK,TECR,SLITRK1,RPL13A,COPE,PNP,TMOD3,LDHA,RPS12,RPS20,MSN,TRIM27,GANAB,RTRAF,EIF4A3,CTTN,CYRIB,ENO1,PELP1,MACROH2A2,STAMBP,RARS1,HNRNPH3,RPLP0,RPL26L1,H2AC7,HSP90B1,MRPS34,JUP,LMNA,EDF1,MYL12B,SAP30BP,RPS14,SF3A1,BRIX1,CHMP2B,NHP2,USP8,NUCKS1,HMGB1,RPL4,GTF2I,POR,CALR,MOV10,CGAS,TOP1,RPL35A,PSMB1,SEC23A,PWP2,MSRB3,SRP72,ILF2,ACTR2,PGM1,RPL15,EIF3E,SMN1,PRDX4,MDC1,RPS13,HSD17B10,SNAP23,PPP1R12A |
| 2.823e-18 | -40.41 | PAN2 (poly(A) specific ribonuclease subunit PAN2) | protein interactions | 9924 | 388 | 189 | 19454 | 5460 |
RPA2,HBB,SPTBN1,HSPA5,RPL27,IGF2BP1,EIF3G,CFL1,CFL2,RPS17,RPL7A,PSMC5,RPS3,SF3B6,GNAI3,CAPZA2,TNRC6C,TP53,CAPZA1,RPL17,RBCK1,RPL3,TRAFD1,DHX9,MAP1B,RPS2,RPL10A,TMOD2,SNRNP70,RPL24,TPM3,ELOC,RPS16,SSBP1,ALYREF,RPL32,EIF4B,CTBP1,CD59,RPL27A,EFHD1,GNB4,PACSIN3,EEF1G,HSPA8,SPECC1L,RPS26,RBBP8,CCT2,SNRPB,CREBBP,HNRNPC,HNRNPAB,RPL10,MATR3,PRMT5,RRAS2,EFHD2,RPL18,RPS23,TUBB4B,TUBA1A,RPS7,RPL28,RPS4X,POLDIP3,RUVBL1,TRIM21,RUVBL2,MYO1B,RPL31,PABPC1,CCT8,CTNNB1,ACTR3B,RPL6,CCT7,HSP90AB1,RPS10,RNF144B,SNRPD3,TCP1,CORO1C,MT1M,SRSF1,TMOD1,RPLP0,RPL26L1,JUP,RPS14,ATG16L1,MYL12B,BRIX1,RPL4,SQSTM1,PAIP2,COL1A2,IVNS1ABP,LGALS8,RPL26,ATP5F1A,NONO,TUFM,CSK,STK38L,RPL22,GNAI2,TXN,TMOD3,YES1,RPL13A,CMBL,RPS12,ALB,CTTN,TUBA1B,RPL15,YTHDF2,CCT5,SMN1,THRAP3,FARSA,HAPSTR1,RPL23A,PPP1R12A,GARRE1,TCOF1,CNN3,RPL35A,PRNP,H2AZ1,SRP14,AIFM1,RPL12,ARCN1,MYL6,PPP1CB,WDR77,YTHDF1,HADHA,NUP50,RPS5,HSP90AA1,PFDN2,MYO6,UBTD1,CHCHD3,GNB1,RPL19,PRRC2A,ACTB,RPL35,DYNLL1,TUBB,RBBP4,SNRPD1,RPL37A,SNRPD2,RPS9,GNG12,RAN,RPS11,CTNNA2,RPL29,MARCKSL1,RPS27A,TOB2,PCGF3,ASF1A,SRSF8,SRSF7,RPS24,BAG2,HSPD1,HNRNPA2B1,HNRNPD,RPL23,HBA1,PPM1B,HNRNPA1,HMGA1,TRIM35,INA,SPTAN1,RPL7,RPLP2,KRT8,RPL9,RPL8 |
| 2.924e-18 | -40.37 | XPO1 (exportin 1) | protein interactions | 7514 | 1479 | 563 | 19454 | 5460 |
MAP1B,PSME1,CLPB,NUP107,CSE1L,HNRNPK,MEPCE,SEPHS1,RPSA,TP53,ESS2,CBX3,CAPN2,BIRC5,GNAI3,PHETA2,ALYREF,ADD1,GNPAT,KCTD3,FZR1,PPIL4,ROGDI,EDC3,BCL10,RPL24,SHC1,AKAP8L,SEPTIN6,LIN7C,BAP1,IRF3,ZBED3,TNFAIP1,HDAC3,METTL22,WDR55,CLU,CDC42,HPS6,RNF146,PHAX,CSNK2B,SRP54,MAP3K3,CDC20,UBA3,DYRK1A,SUGP1,CCNB1,RPL7A,VAMP5,ARHGAP21,PRKACB,GORASP2,BICD2,STN1,PDCD4,IGF2BP1,CDKN2AIP,UBE2H,AP3S2,LSM14A,ABCF1,SCPEP1,RUVBL1,RPS4X,SECISBP2L,ETFB,EEF2,RPS7,TUBB4B,SMARCB1,RPS23,MOB3C,KCTD20,PRCC,GYS1,WDR82,NXT1,PABPC1L,NOB1,CDK17,DBR1,RPS10,SUMO2,MITF,SUMO3,SNRPA1,SNRPD3,HSP90AB1,CHMP2A,PRKX,CNOT2,RPL6,YWHAH,XPO1,YWHAG,DNTTIP1,CTNNB1,ACTR3B,DDRGK1,SPATA2,RIMKLB,ARL14EP,DRG2,CBL,DDX1,CDC23,PEX3,MACIR,DR1,DDX5,UFL1,SRSF2,PACSIN3,TOM1L2,EIF4B,CNDP2,CSNK1A1,LMBR1L,GPN2,SMU1,STAT2,STAT1,POLR2B,ESR2,MYC,HNRNPC,PSMD1,KIAA1191,ATG3,YAE1,RCL1,TCOF1,SFXN1,RPL23A,SNAPC3,IGF1R,CNOT7,HUWE1,DNAAF10,PAGR1,SMN1,RIGI,FBP1,GBE1,CCT5,BLOC1S3,ACTR2,POLR2G,AP1S2,VAC14,WDCP,TFE3,EIF4E2,TRAK2,TNKS,MDM2,NCBP2,EID1,POR,ECD,FAM53B,INPPL1,RPA3,DVL2,MIS12,NF2,FBXW7,MEF2A,CHMP2B,VPS28,ARHGAP1,SYNRG,CTDSP1,PICALM,STOM,OSER1,UBAP1,HNRNPH3,AGAP1,HAUS2,CINP,CCNF,TUBA1B,METAP2,CHRM4,HEXIM2,MSN,TMOD3,COPE,FERMT2,VIRMA,DEK,CEP97,RALB,FBXO7,ASCC1,ARFGAP3,AP2A1,CDC73,PAIP2,MAPRE1,SCYL2,ZYX,NEK9,PRPSAP1,SRSF7,DHX16,GTF3C3,SSRP1,ENKD1,FANCG,TOB2,AHCYL1,ARFGAP1,ANP32A,RAF1,B3GNT2,CSNK1E,GABARAPL1,SCHIP1,CHMP4C,AQP3,POLR2C,RPS11,RPL8,NABP1,MRTO4,SNX17,USP46,SNX18,AGK,EGLN3,STK3,HSPB8,HNRNPA1,SKIC8,WDR12,PPM1B,DROSHA,HAX1,PDAP1,SNRK,SERTAD2,TRIM5,TERT,SNX24,YTHDF1,NDE1,ASB8,TOR1AIP2,LARP4B,MFAP1,ARCN1,AVPI1,FAM91A1,RSRC1,AP1G2,SEC61B,RPS9,TUBB,TAB1,MAT2B,USP5,CDC123,SMARCE1,PRPF31,FAM83A,BRCA1,RHOB,YWHAZ,HSP90AA1,RPS5,LSM14B,ILK,NOSIP,RUSF1,NAE1,ABCE1,TRAFD1,TOLLIP,KPNA2,SNAP29,RRM1,TNRC6C,RPAP2,ARHGAP12,WBP11,URM1,TFCP2,IK,ARPC3,TAB2,SNAPC2,TAF2,CD274,COQ8A,PREP,RWDD1,RPS16,FCHO2,DKC1,SLAIN2,RBM17,TMA16,CSNK2A1,SMAD4,TUBG1,SNRNP70,BECN1,NOS1AP,RPS2,RPL10A,POLD2,FAM53C,KDM1A,ZC3H15,MARS1,HSPA5,SUMO1,GABRA1,SETD3,CFTR,RPA2,EIF2B3,UTP15,ACACA,RPS3,FKBPL,ZNF330,EIF2S2,KCTD9,BUB3,CEP41,CSTF3,SMURF1,TFEB,ADPRM,MAT2A,CEP85,SUB1,RPS17,PTTG1,CCDC174,SERPINB1,ANAPC4,PABPC1,RBM3,TOP2B,RUVBL2,RPAP3,EFNB1,RTCB,KRAS,NUP42,RPL28,RWDD4,MAX,ERRFI1,RANBP1,SOX2,CRTC2,HPCAL1,CSTF2T,TNPO2,RPL18,AAMP,TNIK,SRSF1,MAGED2,AFTPH,EIF2S1,GSTCD,STK4,UTP6,DIS3L,TBC1D5,IQSEC1,FKBP4,HSPB1,ANKRD50,DRG1,PYM1,SLU7,SNRPA,XRCC5,HSPA8,HDAC5,SPATA2L,EP300,AKAP1,EMC1,STAU1,GNB4,NUP62,PIH1D1,LORICRIN,NFKBIA,NFKBIB,GTF2F1,GTF2F2,USP16,TRIM29,FBXO22,SNRNP40,APLNR,PPP5C,RUSC2,GFUS,MLF2,DNAJB6,TFPT,SEPTIN7,RING1,HAPSTR1,LSM4,TOM1,THRAP3,BACH1,FBXO25,TICAM1,CTNND1,RPS13,EIF3E,COMTD1,TBK1,YTHDF2,SMAD1,PPP4C,SRP72,SSU72,UBP1,EHBP1,PWP2,SEC23A,EIF2B5,POLR2I,PRNP,EIF2B2,ZBTB2,G6PD,NFKB1,PKIA,CDC37L1,HDAC6,SLC2A1,SSX2IP,STYK1,NCDN,SIRT7,PRPF4,PNO1,SYVN1,VIPR1,SQSTM1,ARPC2,EIF5B,HMGB1,RPL4,DESI1,NHP2,FBXO9,AATF,CPSF4,RPS14,ATG16L1,CCND1,EEF1E1,RBMS2,EID2,CDK1,GRM2,PDCL,SMAP2,WDR45,TRIM24,UBE2I,ARMC6,EAF2,SMAD5,SEC13,DEPDC1B,TUFM,USP14,AR,NONO,CHORDC1,ZNHIT3,TXNIP,STK24,NCKIPSD,CASC3,TRIP4,ZC3H7A,TRIM26,G3BP1,TRIM37,AP1M1,ANP32B,E2F4,NUP153,GFPT1,EZH2,GPBP1L1,RBPJ,PHB1,TSG101,ARHGAP25,HP1BP3,NOP58,OCRL,CCAR2,CNTROB,FRA10AC1,P2RY10,ATG7,EIF3D,CDKN1B,CAMSAP2,LRRC57,UPF3B,RTKN,TRUB1,HACD1,CRY1,NUP50,RNF10,TTC1,NPTN,COIL,POLA2,FBXL4,TGFB1I1,FAM234A,NPY2R,ETF1,PPARG,TBC1D17,PSRC1,PELO,RAN,AP2M1,CDC7,RPL35,CHP1,SNRPB2,GNB1,CUL3,GRB10,CFAP20,GPR17,PDE4B,OTUD7B,RIOK2,BLOC1S5,MCM8,WDR20,LMNB1,PLEKHJ1,NTRK3,RIT1 |
| 2.944e-18 | -40.37 | establishment of protein localization | biological process | GO:0045184 | 1291 | 521 | 18204 | 5365 |
CEP41,IPO8,RAB32,KPNA2,SRP54,SAMM50,CNTN2,AP1AR,TRAK2,SNX2,AGAP1,RAB3C,CHCHD4,SLC15A2,ARCN1,CHMP4C,PPARG,SCFD1,LIN7C,DESI1,ANKRD50,YIF1A,SGTA,RAB39B,RPL23,BET1,CCDC22,RABIF,CD3G,SPCS2,GLE1,GABARAPL2,MLC1,TMED5,UFD1,TSPO,RAP2A,HOMER3,GOLGA7B,CHMP5,STX12,CETN3,SYNJ2BP,KIF3B,EHD1,SSR1,SSR2,VPS4A,MDM2,GNPTG,SDCBP,SRPRB,SPCS3,TP53,ARF1,BCS1L,SVBP,STK4,TMED7,TMEM147,RPAIN,TOMM70,NETO1,DLG4,DDIT3,AZGP1,ARF4,NUP42,COMT,TRAM1,ARHGAP1,SLC15A1,HSPA8,SCAMP5,ADORA1,SNX20,LARGE1,CHMP1B,RAB31,SPCS1,STRADB,NUP35,TRIM23,CTTN,GPR89A,SPRN,TBC1D13,ATAD1,PEX3,TOMM20,VAMP2,TIMM23,RAB37,PLEKHA8,ATG3,CDKN1A,HSP90B1,H1-5,EXOC8,EXOC5,ARF6,TBC1D17,RAB9B,WDR83OS,YWHAB,LMAN1,RP2,SEC61A1,TBC1D5,EXOC3,RAB2A,SEC13,SNX14,ING1,RAB11A,ERLEC1,VAMP7,RAB6B,GRPEL2,APPBP2,PPT1,RANBP6,RAF1,HINFP,SSR3,RHOB,SNX22,RANGRF,SEC22A,CORO1C,GOLPH3L,CDK5,STX1A,RAB6A,CTDSPL2,VPS28,EMC6,RAB11B,ARL4D,RAB1A,AGAP2,FKBP1B,BLOC1S3,RUVBL2,AP2M1,PLEKHF2,COG1,VTI1B,CAV1,MCOLN1,NECAP2,TNKS,VAMP5,CCDC186,ARL6IP5,EGR2,MTM1,PSEN1,AP2A1,TNPO3,HSPA5,IFT22,SMAD2,SNX3,TRAM2,ARFIP1,GOSR2,TOMM40,ZFAND6,GOSR1,HSPB1,FAF2,SLU7,FCHSD2,DNAJC19,ZDHHC15,ABCB9,PREPL,PMPCA,RAB4A,SEC61G,HSP90AA1,STX8,BTF3,SYNDIG1,UNC119B,STK3,SNAP25,CNIH4,MTCH2,GDI2,HNF1B,NXT1,REP15,RAB18,RAB9A,YWHAH,SCG2,HGS,RAB28,AFTPH,PRKCB,JAKMIP1,SYNGR1,RABL2B,VIPAS39,WDR11,CSE1L,EDEM1,HPS6,TTC8,COPZ2,OS9,MACROH2A1,XPO5,ACTN4,CBLN1,POLA2,NAPA,ATP1B1,FIS1,BECN1,RAB3A,RAB13,EMC1,VTA1,CBL,AIP,AP5M1,ARL5B,BAG3,SEC22B,RAB29,EMC4,JAGN1,EMC2,LCA5,ZFAND2A,LRWD1,CHP1,TIMM10,SNX33,VPS4B,AP5S1,ZDHHC24,TOM1L2,TVP23B,PPY,RAB3B,TMEM115,TOMM22,CMTM6,TRIM37,NAPG,PEX13,RABL3,EIF2D,RAB1B,VAMP8,TOMM6,SEC61A2,KDELR1,CTSA,SNX24,SYS1,SNX17,FBXO7,SEC62,MAIP1,EMC8,EMC9,GOLGA7,AP2S1,STX17,TOMM7,AP3S2,TIMM21,BET1L,TMED3,BICD2,SNX11,GORASP2,PIK3R2,SNX1,SRP72,AGK,EHBP1,PIK3R1,RAN,CCDC47,SNCG,MTX2,YWHAZ,MIR301B,TRIM3,CPLX1,NEO1,GPIHBP1,SURF4,ARL4A,STX10,RAB8B,TOM1,PHAX,ZFAND2B,ARFGAP3,STX5,SEC23A,PAFAH1B1,SNX10,RAB22A,NUP107,NLGN1,ZMAT3,PHB2,HIKESHI,SQSTM1,PARP11,LEP,RAB40AL,STX18,MGARP,OLFM2,PPID,DAG1,KCNJ8,TERT,DRD1,LAMP5,TIMM8B,TRAM1L1,WBP2,SRPRA,CBLN4,PML,NUP62,NECAP1,EXOC2,EHD3,ARL6,TRMT10B,VPS54,PICK1,VAMP3,YIPF5,RAB35,VIP,RAB19,STX6,SNAP23,CD2AP,NDP,USE1,DNLZ,VPS16,RAB5A,NUP37,VMP1,RILPL2,SRP14,TIMM13,TFRC,RAB33B,NXT2,CLTRN,YKT6,LAMP3,SEC63,ATG16L1,UBAP1,SPTBN1,ATG4A,CD63,XPO1,ZDHHC17,SGF29,HDAC6,TESC,LIN7B,SELENOT,STX16,TMED9,STX11,GRPEL1,ZDHHC4,CLU,RINT1,SYK,ARFGEF1,RAB14,UBL4A,DERL2,SCG5,MACROH2A2,CD36,CHMP2B,VPS18,SNAPIN,OPTN,SCAMP2,XPOT,SMYD3,CHMP2A,EDNRA,TIMM29,TXNIP,SAR1B,PEX5L,SFN,AQP11,HM13,PPP1R10,CACNG3,TIMM17A,SFT2D2,SMURF1,FAM53C,DNM2,ATG7,MCL1,TSPAN17,GUK1,EXOC1,LAMP2,AHCYL1,TOM1L1,TRAF3IP2,SEC22C,BAX,RTP4,ERP29,CHMP1A,CAMLG,CETN2,DNAJC27,ACVR1C,BBS5,YWHAG,GPM6B,IMMP2L,RAB23,MYO6,MACIR,MX2,KPNA1,ZDHHC14,ARL11,COPE,DUOXA2,SNAP29,CLIP3,MIR130B,MIA2,EMC10,SNAP91,VPS33A,VPS26B,TNPO2,AP1G2,TMED1,AP1S2,HSPD1,CPLX3,PRKCE,SYVN1,KPNA6,FAM91A1,TOMM40L,RAMP3,TUBA1A,RAB27A,DERL1,BCAP29,SLC4A8,TSG101,STXBP1,VLDLR,STX7,ARRDC3,NUP50,NUP153,ATG4C,SYNRG,SNX12,CCHCR1,CYB5R4,XBP1,FHIP1B,SEC61B,TIMM8A,KDELR2,RAB3D,SLC1A1,TNFAIP3,VPS26C,RALA,IFT25,AP1M1,RAB5C,ENY2,ROMO1,SNX5,NFKBIA,CAMK2G,NSG1,CALR,SNX18,VPS26A,TMED4,GABARAP,FKRP,SELENOS,TSPAN10,VPS39,PPP3CA,FAM53B,ARFGAP1,PEX26,LMNA,AKT1,AIFM1 |
| 2.974e-18 | -40.36 | CUL4B (cullin 4B) | protein interactions | 8450 | 692 | 299 | 19454 | 5460 |
STAT1,MATR3,SNRNP40,CBX5,SMU1,PRMT5,PHF21A,CIRBP,FBXW11,H2AZ2,COP1,RPS26,COPS7A,HNRNPC,RUSC2,LDHB,HNRNPAB,PSMD1,SNRPB,CPSF2,BAG3,MLF2,HNRNPA0,TRA2B,UBE2D3,PHB2,SAP18,SNRPA,HSPA8,DDX5,RAMAC,EP300,CTBP1,EIF4B,CNDP2,PACRG,RPL27A,SNRPD3,TRMT61A,HSP90AB1,SIN3A,SRSF1,WDR82,DCAF5,DDX1,DDX50,DCAF4L2,RPL6,PSMA1,HNRNPF,HMGN4,RPS4X,RWDD4,IMPA2,TFG,HNRNPDL,RPL31,PABPC1,RBM3,EWSR1,RTCB,DCAF8L2,TUBB4B,MTA2,RPL18,DCUN1D5,SOX2,RPS7,EEF2,CSTF2T,BUB3,PSPC1,RPS3,DNAJC10,DTL,ATP1A1,IGF2BP1,NUDT1,MORF4L1,RPL7A,FBXO44,PCBD1,GCNT3,HDAC3,RBM22,H2AC13,OIP5,TOMM20,HSPA5,RGS2,MARS1,BAP1,RPL27,HNRNPH2,RPA2,UBE2M,CAND1,RPS16,TMPO,TWIST2,SYNCRIP,ALYREF,TUBG1,SNRNP70,RPL24,H2AC4,RPS2,KPNA1,USP15,KARS1,MTMR12,COPS5,GAPDH,NEDD8,H3C1,CRYBA4,HNRNPK,KPNA2,TMEM33,PHF1,FKBP8,POC1B,RPL3,DHX9,CBX3,DCAF12L2,HBP1,BIRC5,RRM1,STRBP,CDK4,TP53,STARD7,ACTB,TUBB,RBBP4,RPL35,ERH,JAK2,ENO2,SNRPD1,SNRPD2,FAS,BRCA1,DCAF4,TNFAIP8,HSP90AA1,SCFD1,RIT1,NLRP3,CUL2,CUL3,MCM3,SRM,POLA2,ZFP64,TTC1,RNF7,ANXA7,SLC25A3,WDR77,TOR1AIP2,ASB8,PRDX3,DET1,COPS7B,NOP58,RPL7,SRSF10,PPIA,DHX15,RPL9,RPL8,FBXO32,IGBP1,RPLP2,COPS2,RPLP1,HP1BP3,SKIC8,CSTA,DCAF11,LYZ,HNRNPD,CLPX,PRDX1,HNRNPA1,TRA2A,ZNF207,SIAH2,RBBP7,RPS27A,SRSF4,AP1M1,UBE2A,IMMP2L,COPS4,SLC25A5,ZYX,HSPD1,PPAN,NDUFA4,HNRNPA2B1,PCNA,MRPS11,FHL3,SRSF7,RPS24,EZH2,SNRPE,SART3,RPL29,NUP153,CCS,SAP30,DCUN1D3,TXN,UBB,STUB1,GAB1,TUBA1B,POP7,ENO1,TRIM27,SYT2,GSK3A,GANAB,RTRAF,RPS20,PTEN,DCAF16,TXNIP,PIP4K2C,STK11,SMAD2,AP2A1,NONO,AR,TUFM,NF2,NUCKS1,RPL4,FBXW7,MBD3,CDC42EP4,HELLS,RPA3,SIRT7,MTDH,JUP,SNAI2,HSP90B1,OXSR1,HNRNPH3,RPL26L1,RPLP0,RPS14,WDR5B,SNRPN,ST7,DCUN1D1,RPL35A,PRNP,MDM2,AIFM1,RPL12,KRR1,ACTA2,NLRP1,TES,CRBN,EIF5A2,TIAM1,FOXP1,OSBPL8,H2AC14,NFKB1,TLE1,HDAC6,SUV39H1,HUWE1,SEM1,NOC4L,FN3KRP,SNRPG,VPS16,SFXN1,RPL23A,HAPSTR1,MRFAP1,SEPTIN7,HSD17B10,ILF2,FBP1,MTA3,SOCS3,EEF1A1,SOX9,RPL15 |
| 3.047e-18 | -40.33 | regulation of cell communication | biological process | GO:0010646 | 3541 | 1257 | 18204 | 5365 |
CPLX1,MIR30E,PRKACB,YWHAZ,OSM,ZNRF1,PIK3R1,SLC6A6,NR2E1,NR0B1,CUL3,PIK3R2,CCNB1,RXFP2,MIR218-1,OPRK1,NIBAN2,FZD4,PRELID1,FGF23,PPM1B,FABP5,BCL9,CARD19,RPS12,TLR1,RNF115,TIMP1,SAMHD1,NF2,LAMTOR2,MIR874,PRRT1,RALGAPA2,IL23A,SLC38A2,VEGFA,RGS6,UQCC2,GTF2H2,PRDX1,LAMTOR3,CSH1,PBLD,RB1CC1,IL18,NECTIN2,PDE4B,MIR140,PIK3CG,THY1,INSIG2,RNF41,FASLG,TNFAIP8L1,SCHIP1,BACE1,ICAM1,TCIM,NLGN1,RGS7BP,NTF4,NLE1,PAFAH1B1,PIK3CA,TIAM1,CD47,IL17F,F7,ZFAND2B,MIR15A,ROCK1,PDCD4,P2RY12,LYPD6,NEO1,STAU1,MIR183,TLR2,MIR373,RAB5A,SLC12A2,CYP1B1,DMPK,CLEC12B,DUSP9,CTNND1,CYRIB,TBK1,PPIF,VAMP3,PICK1,CSNK1A1L,DIRAS1,JMJD8,MAPKAPK5,NUP62,PDE2A,WBP2,MAP2K6,NPPC,NHERF1,NPSR1,DUSP6,CCL2,SYP,PSD2,OPRL1,MIR16-1,CHRM3,CACNB4,DRD1,PIH1D1,SCG5,TXNDC12,ACVR1B,TMBIM6,CD40,ARFGEF1,FGF16,SYK,BFAR,STK11,CREB3,TRIM5,CCAR2,SELENOT,FBXW7,RGL2,NOG,S100A8,PRR5L,HDAC6,ZDHHC17,MIR101-1,KCTD10,SCYL2,SPTBN1,EGFL7,KBTBD6,DUSP1,BIRC2,LACRT,TRIM32,ASIC1,OCIAD2,SH2D1A,MCL1,TLR9,PLCB1,LEPROTL1,HDAC3,TMEM204,MIR96,CDC73,TNIK,PPP1R10,NACC2,GRIA2,SEMA4C,SYT4,PEX5L,SIPA1L1,SAR1B,CLEC6A,MIR204,DSTYK,WNT10B,EDNRA,NMI,MAD2L2,GPR65,SLC35C1,HHIP,OPTN,LPAR2,UCN,VPS18,CD80,CHMP2B,CNRIP1,AKT3,CA2,FAM89B,MIR1224,ERRFI1,PPP2CB,CDC42SE1,GPR137,TMBIM1,OR2AT4,DAPK3,SPRY1,HAX1,PRNP,IQSEC1,GRAP2,UBE2K,ELF1,MMP14,DDX1,KPNA1,MOSMO,LRRTM1,ACSL4,ACVR1C,TMEM100,MIR223,DNAJC27,PYDC2,CD86,ACAA2,MMP9,PTP4A3,ASPM,GNAQ,GADD45G,GNAO1,PADI2,BAX,EIF4E,TRAF3IP2,EFCAB7,MOB3B,IL6,NDST1,AGPAT1,PATE4,FAS,KIT,PID1,XBP1,TSPAN5,MIR320A,MET,DLK2,SOD1,AR,UBE2D1,CNR1,CAAP1,PAIP2,MIR130A,PAK2,TGFBR2,MIRLET7B,MIR125A,USP46,FGF1,NR1H2,RPGRIP1L,NRP1,PCSK9,PLA2G5,PPP3R2,TFG,PIP5K1A,PPP5C,TSG101,RGMA,MIR10B,PARL,CDK5RAP3,SYVN1,CPLX2,PRKCE,TMEM88,GLCE,AKT1,SIAH2,TGFB3,IL1B,MIR182,ARFGAP1,SLC6A1,FAM107A,PPP3CA,HERC4,WNT7A,RPL26,ITGA2,SLC25A31,GPC1,PFKFB2,DUSP26,TMED4,AGR2,TLR6,MIR675,FBXO9,CALR,NSG1,TAX1BP3,SIRT7,NFKBIA,SAP30,CIBAR1,IGF1,LPAR6,CNOT2,UBE2W,ENY2,SPRED1,SGMS1,UCP2,MT3,KICS2,NPVF,INPP5E,OXTR,RETN,RBBP4,GH1,TNFAIP3,RGS5,MAP1B,VDR,TXN,BAK1,GSTP1,GID8,NREP,PPP2R1A,IRAK4,TNFAIP8L3,CAMKV,SUFU,HOMER3,HELLS,KLHL22,TRIM52,F10,FCMR,UFL1,SV2B,SLC16A1,MIR503,MIR212,SLC15A2,MLF1,CYP27B1,RBCK1,TRIM44,TRIM15,SIAH1,LGALS3,S100B,HINT1,C1QTNF1,ATAT1,MIR198,MIR195,FAF1,LARGE1,LAMB2,PTPN1,GHR,HSPA8,ITGAV,ACKR3,GABBR1,TMEM33,ARHGAP1,PCGF2,MIR26B,SEC14L1,JADE1,RPS15,IFI6,TLR4,APLNR,DLG4,CER1,HOMER1,TMEM14A,ZBED3,CRBN,PIP4P1,STK4,TP53,SDCBP,PPFIA3,TNFSF10,KCTD12,MDM2,NEK7,SOD2,DDX5,TNFAIP6,AVPI1,SOST,MAP3K3,SYNJ2BP,MIR1-1,CASTOR2,NLRP3,GJA1,YWHAB,MIR214,MIR17,CTSD,CSNK2B,LYNX1,ARF6,IRF4,TIFA,TMSB4X,MDFI,FOLR1,LSM14A,TNFAIP1,GPR89A,GNG7,TBC1D10C,RB1,PTPMT1,CITED1,SLC25A5,NLRP2,NPY5R,GREM2,CASP4,EID2,ILK,RNF152,CXCL12,BCL6,RHOU,CTDSPL2,PFDN5,HFE,CDK5,FGF7,STUB1,LURAP1,PLG,MZB1,CHRDL1,DUSP10,ARHGAP12,MIR98,TBC1D24,EMILIN1,HECW1,FBP1,CX3CL1,BRMS1L,NDUFAF2,MUL1,GRM8,RBPJ,TWSG1,FGF3,TNF,RUVBL1,PDIA3,LRRTM2,PHB1,RPA2,EDA2R,ING1,SEC13,AVPR1B,SLC25A4,TESPA1,TACR1,MYD88,NPTN,IL4,GADD45B,BEND6,OPHN1,HTRA2,TMEM127,CYTH1,LDLRAD4,HSPA5,SOCS5,ATP2C1,MIR146A,TULP3,CD81,CD46,CBLN2,MIR149,FXN,IGFBP3,DEPDC1B,MAVS,TMEM101,FURIN,CSNK1G3,EEF1E1,DOK4,TYROBP,CPTP,GPR35,ANAPC15,LANCL2,EFNA5,ING2,STAMBPL1,RUVBL2,CDKN2AIP,DKK3,SWAP70,MAD2L1BP,MYORG,REN,BCL10,MIR132,TEDC2,SCG2,IL12A,RWDD3,TPD52L1,FRZB,RASL10B,YWHAH,MIF,CCL3,HNF1B,RNF34,OPRM1,STK3,FBXO8,CSF2,BTN2A2,IL6ST,HEY2,IRF3,MAP3K12,EPHA4,TRIM68,TLR3,DYRK2,AKAP12,UBAC2,SPEF1,RGS19,KCNB1,CCL5,CDC42,PPIA,NUPR1,DUSP19,SOCS2,CSNK1E,IFT172,FERMT2,FLCN,MIR302B,SFRP1,IGF1R,ANKRD6,SOX9,STAT2,RHEB,NDFIP1,CBL,IL1R2,HCST,GHRL,RGN,PROK1,CSNK2A1,BANF1,DNAJB9,IGBP1,DLG1,CHST11,RAB3A,BECN1,SNAI2,LTBR,FIS1,DICER1,CBLN1,CYTH2,DHX15,KDM1A,PELO,ING5,IL5,SLC38A9,FKBP1A,MIR29C,TLR7,GRAP,EIF4EBP2,NUCKS1,WDR11,IGFBP4,SYNGR1,SAP30L,CCR1,MAP2K1,PRMT2,HGS,VAMP8,DKK1,RABL3,FEM1B,FAM20C,GLRX2,SPP1,GAS8,CA8,COL3A1,RNF167,HAND2,C9orf72,ADRB2,HCFC2,SEMA5A,SETD9,ISG15,CCR7,MAP2K3,DUSP3,PPFIA2,OSBP,MIR346,FRRS1L,SHISA2,TLE1,JAGN1,OTUD7B,MIR9-1,TRIM8,SESN3,LTB,RAB29,IRF1,TRIM3,BRMS1,AFAP1L2,SNCG,MIR100,CTNNBIP1,SHOC2,BPIFB1,NTRK3,MIR296,NTRK2,LMO3,CCDC3,BMPR1A,MECP2,SMARCB1,NDC80,IVNS1ABP,PRMT6,AKR1C2,NCDN,NFE2L2,TICAM1,FBXO7,MIR29A,LPXN,UBASH3B,BMPR2,SLC38A1,ADGRG1,SEMA7A,CDK20,MIR34C,DAG1,ADRA1A,SRC,SH3BP4,ANGPT1,EXT1,KCNJ11,FAIM,TNFSF12,MTMR2,EPS8,TRIM21,WIF1,ATF4,HNRNPK,LEP,SQSTM1,HEXIM1,PHB2,SERINC3,TAB2,DOK5,PLCL1,IFNG,MIR34B,ARHGAP5,BIRC5,RNF146,DYNLL1,GPR37,LGR4,RAB8B,PDCL,PRKRA,NLGN2,GADD45A,TRAF6,FXR2,FKTN,TICAM2,MIR222,NDP,LAMTOR1,CD38,CD2AP,MIR181D,GSKIP,TRIB1,JPT2,NINJ1,C2CD2L,GRM2,CCL19,SYBU,SOSTDC1,PML,BMPR1B,TASL,HCLS1,TAFA1,CHI3L1,DISC1,KCTD16,IGSF11,GNA11,SRI,SPATA2,NFKB1,CHN2,CRADD,TERT,CISH,WDR83,RALB,OTULIN,MINAR1,CLU,MIR205,STAP1,ADIPOR1,STK38,NKX3-1,ATF3,NFKBIL1,RPS7,FCGR2B,MIR24-1,SMAD3,KCNJ10,DUSP22,CD63,ALKAL1,LMBR1L,SLC7A11,SARM1,GIT2,TRIM62,TFRC,SELENOK,DDIT4L,CCN3,TAF9,CRHBP,TMEM108,RAP1A,EIF4A3,PIK3AP1,NGDN,ELAPOR2,PEBP1,UBE2B,HACD3,GLIPR2,PCK2,RTN4,EMP2,RGS10,GNAZ,ILDR1,SMURF1,MIR30B,FGFBP1,MIR21,CACNG3,INHA,MIR519D,HADH,VWF,MIR375,CPNE1,LILRA2,MSX2,ANAPC2,TTC23,RRAGB,VAV2,SIN3A,SYN3,ZNF592,TCF21,NDUFS3,MIR210,SNAPIN,PMAIP1,CD36,TPT1,CPLX3,ENO1,GRIK1,MIR885,OTX2,MIR186,TRIM34,PRL,PPARA,PELI1,FLOT1,TRAF7,VEGFC,GPR37L1,GPC4,SLC1A3,PAK5,GRM1,MIR10A,TMEM196,MIR449A,ADRB1,NEUROD2,BRAP,MIR185,FGR,UBE3A,IL12B,RNF14,LRRC4,FOXP1,YWHAG,PEA15,MIR107,BGLAP,PCDH17,UBB,DLGAP4,ERP29,USP2,STAMBP,ABHD6,RSAD2,CSK,EIF2AK2,CD14,MIR206,GNAI2,ADRB3,AATF,GRIA1,HTRA1,CARTPT,SLC8A1,DIRAS2,UBE2N,RRN3,MIR497,TRIM24,NCOA5,CRKL,ARRDC3,MIR221,MIR573,BST2,IRAK1BP1,TTI2,STAT1,TSPAN15,TIRAP,BCL2L1,JAK2,LIMS2,PTEN,P2RY10,STXBP1,SLC4A8,DEFB114,G0S2,FGD2,BAD,UGCG,GRID1,SSX2IP,DVL2,RAMP3,CRY1,MIR545,GSK3A,NOP53,MIOS,STARD13,ZMYND11,UBE2V1,LMNA,P2RY4,MIR1271,FAM53B,SDHAF2,ARHGAP15,DRD3,SELENOS,TANK,SMAD4,GRB10,MIR99A,GABARAP,PRMT5,MIR92B,BOK,EP300,SNX5,PDCD10,VDAC2,KLK5,TMEM106A,CYFIP2,GPX1,RALA,CTNNB1,SLC1A1,MIR95,CTSK,HYAL2,PRKCQ,RELL2,GPNMB,JUP,SLA2,MIR106A,SESN2,ZNHIT1,TMEM237,RAP2A,TSPO,UFD1,PDE9A,F11R,CSNK1A1,CCDC22,RPL23,SFRP4,PAQR3,SRARP,RACGAP1,LIPA,PPARG,CLSTN3,EGR1,GAPDH,IKBKB,IL34,TGFB1I1,CNOT7,NR4A2,EPO,TPBG,SLC6A4,FSTL1,IL7,OSBPL8,CHRNA7,CHRNB2,EZH2,FZD6,YTHDF2,LEMD3,RPS20,NCSTN,MIRLET7G,PYCR1,FGF22,NKIRAS1,ADORA3,ADORA1,FGFR1,P2RY1,MIR340,PRDX2,NONO,GHITM,DHRS3,EYA3,SLC4A10,DDIT3,LRRC8A,FAM13B,NETO1,PTPN11,LCMT1,ARF1,SPPL3,FKBP8,CTSC,MIR133B,CCNY,LPAR1,CXCL8,DIPK2A,RRAGA,RGS1,MIR34A,ARHGAP21,UBE2D3,ZNF451,ITGA6,AZI2,CLEC7A,EIF4E2,AIPL1,ACVR1,CFTR,NEFL,PRKCA,DDR1,PLSCR1,UFM1,CAPN1,RHOH,CDH11,PIP4K2C,INA,MIRLET7C,GAS2,CCR2,F2,HAPSTR1,SPHK2,JPH4,ZNF622,RELL1,INPPL1,PSMD10,VAMP2,ATAD1,RPF2,CGAS,MIR424,LGI1,CTTN,ADNP,STRADB,NKIRAS2,GUCY1B1,FBXW11,KLK6,EPHA2,PTK7,STX1A,CDC42SE2,RGS2,NTNG2,MPIG6B,YTHDF1,MAPRE2,HMGB1,MME,CXXC5,ABHD17A,AGER,HRAS,MIR23A,PYCARD,MIR361,CD226,PLEKHF1,TMEM198,CXCR4,SLC39A10,RAF1,ROCK2,IL10,MAP3K11,DDRGK1,ADIPOQ,CRLF3,RBBP7,FGF17,LBH,VAMP7,TRIM6,SNX14,LY96,RPS3,TRAF1,MSX1,MIR145,TRAF2,CX3CR1,DBH,SNX3,SMAD2,MIR421,MIR342,BRCA1,BUD31,ARHGAP19,MIR208A,CNKSR3,ZMPSTE24,GFI1,CD4,RNF113A,TRIM26,PTN,HBEGF,TNKS2,PSEN1,MTM1,ARL6IP5,PPP1R2,EGR2,LILRB4,FAM83B,MIR324,TAB1,GPBAR1,HTR1A,TNKS,USP8,RC3H2,ACHE,SLC20A1,SOCS3,IFNB1,TRIM11,CAV1,MEF2C,LYPLAL1,MSTN,CAV3,CDKN2D,PIM2,VGLL4,FKBP1B,HSP90AB1,TAX1BP1,CD28,INPP5K,HTR2A,DDT,PELI3,SNIP1,APLN,ATP6AP2,CYP26A1,SNAP25,AKIP1,FGF12,SMAD5,SOCS4,USP15,SOS2,GLRA1,RIMS3,PREPL,DLX1,LRRC14,WWP2,HCRT,DOK6,CASK,G3BP1,PEG10,DAPK1,CDC20,IFNAR1,GPR17,MIR490,HSPB1,MIR142,ZFAND6,MYC,IER3,CREB1,MIR126,FRMD8,TNR,CTNNA1,AIP,ARHGAP25,TRIM22,MIR20A,CCL21,PRCP,ATP1A2,PICALM,LITAF,SLC35F6,ADAMTS20,IFI35,MIR1260B,ACTN4,MIR708,CAV2,TMEM170B,TMOD2,RIT2,ATP2B4,MIR200C,CHRM1,NLRP6,H2BC11,IRF7,MAD2L1,COPS5,RNF126,CRHR1,OAS1,RAP1B,PAGR1,PRKCB,CHGA,SHC1,DYRK1A,GCLC,SOX2,PTPN22,PDE8A,NFKBIB,ENHO,MTDH,CREBBP,PROX1,CYTH4,GREM1,DDIT4,MIR152,CDH13,IL1A,TGFB2,CHP1,CRYBA1,PAK6,MBD5,KRAS,NOTCH2,PAK1IP1,RIMS4,ACTA2,SPRED2,NCK1,FGF10,GKAP1 |
| 3.327e-18 | -40.24 | RBM8A (RNA binding motif protein 8A) | protein interactions | 9939 | 442 | 209 | 19454 | 5460 |
RPL10,ESR2,DLST,RPS26,H1-10,CHTOP,FTSJ3,H2AZ2,SNRPB,MYC,SAP18,HNRNPA0,UFL1,STAU1,SSR3,SF3B1,DDX5,SNRPA,PEBP1,SLU7,PYM1,DDX39B,RPS28,NUFIP2,EIF4B,RPL27A,ZC3H14,RPS10,EIF2S1,NOB1,LYAR,SUMO2,SRSF1,DRG1,MAGOH,AGR2,PPIB,DDRGK1,IFI16,RPL6,RPL28,RPS4X,KRAS,PSMA1,RUVBL1,EWSR1,RUVBL2,RPL31,PABPC1,RBM3,APTX,RPL18,RPS23,PDHA1,SEC61G,SOX2,RPS7,EEF2,TRMT1L,TOP3B,SUPT5H,DHX38,SRPK2,EIF2S2,SRP54,SEC61A1,RPS3,PDCD4,IGF2BP1,ALKBH5,UBE2H,EIF3G,RPS17,RPL7A,ZC3H15,EIF4E,MARS1,RPS15,SMG5,RNF113A,RPL27,UGDH,BAP1,TMEM263,UBE2M,SEPHS2,HBB,CDC42,SPTBN1,RBM42,RPS16,RPS27L,ALYREF,RPL32,RPS2,SMG8,LSM3,RPL10A,RPL24,CHCHD1,SNRNP70,COPS5,TPM3,PGAM1,CTSC,RPL17,SRPRB,ABCE1,RPL3,DHX9,SNIP1,CAPN2,NUPR1,RPSA,SNRPB2,ERH,RPL19,PRRC2A,EIF4A2,RPL35,RPL37A,SEC61B,RPS9,EIF3K,RPS5,FYTTD1,LMNB1,RNF40,RPS29,NOP16,G3BP2,UPF3B,MFAP1,LARP4B,MTX2,RPL7,RPLP2,RPLP1,RPL9,RPL8,PHB1,HNRNPD,PPP3CA,PDAP1,RPL23,HNRNPA1,EIF3D,HMGA1,UNC119B,SSRP1,PCNA,RPS24,TRIP4,HNRNPA2B1,RPS11,RPN1,CHMP4C,RPL29,RAF1,ANP32A,DEK,RPL22,MAGOHB,ZNF622,RPL13A,GSK3A,RPS12,RPS20,EIF4A3,POP7,MAPRE1,CASC3,BRIX1,RPL4,MTDH,SOD1,PNO1,RPLP0,RPL26L1,P3H1,LSM2,EDF1,EIF3J,RPS14,SF3A1,CDK9,NCBP2,ZBTB2,NOP9,RPL35A,THOC1,TOP1,PSMB1,SRPRA,RPL12,SMG9,RPS13,FBXO25,EIF3E,CAMK2G,THRAP3,ZC3H11A,RPL23A,NKRF,ILF2,SRP72,RAD23B,DAP,RPL15 |
| 3.402e-18 | -40.22 | G3BP1 (G3BP stress granule assembly factor 1) | protein interactions | 10146 | 799 | 336 | 19454 | 5460 |
SOX2,ISG15,TNPO2,KIF2A,RPS7,TOP3B,HEXA,RANBP1,ZRANB2,MTA2,RPS23,RPL18,MOB3C,PDHA1,TRIM21,RTCB,ACTR1B,RPL31,LSM14A,PABPC1,RPS4X,RAB18,YWHAH,XPO1,CTNNB1,DDRGK1,IFI16,DDX50,CNOT2,WWP2,RPL6,DDX1,HSPB1,YWHAB,MAGED2,RPRD1A,FUBP3,DUSP6,CCT7,FAM98A,RPS10,TCP1,AASDHPPT,RPL27A,NUP62,ZC3H14,EIF4B,NUFIP2,FDFT1,PIH1D1,EP300,DDX5,CCDC9B,RFC4,RPS28,SPECC1L,UFL1,TRA2B,FXR2,STAU1,HMGCS1,BTF3,BAG3,MYC,APOBEC3B,SFN,HNRNPAB,LDHB,RPS26,FTSJ3,H2AZ2,H1-10,PRMT5,SMU1,VDAC2,IRF2,CMTR1,POLR2B,RPL10,APEX1,MATR3,STAT1,RPAP2,ACTR1A,RRM1,ATP5PB,TP53,RPSA,RNF8,GNAI3,TFRC,IK,CAPZA2,RPL3,SLC16A1,NOSIP,SLC25A11,MEPCE,RPL17,CTSC,NEDD8,CSE1L,KPNA2,TOLLIP,HNRNPK,SRPRB,PPM1D,TMA16,COPS5,GAPDH,COX5A,LSM3,KPNA1,RPS2,RPL10A,MAP4,SNRNP70,DSTN,METAP1,COQ8A,SYNCRIP,COX4I1,RPL32,DKC1,CDC5L,CAND1,IFRD2,FZR1,RPS27L,AGO1,HEXIM1,UBE2M,LEMD3,RPA2,EIF2B3,HNRNPH2,LSM12,RNF113A,GFM1,PRDX6,BAP1,RPL27,BANF1,EIF4E,MARS1,HSPA5,RPS15,WDR3,RBM22,RPS17,TIA1,CFL1,SLC25A1,SMARCA5,TNFAIP3,RPL7A,IGF2BP1,OAT,ELAVL2,ATP1A1,UBE2H,SPOP,EIF3G,ATP1B3,RC3H2,CALML5,SRP54,EIF2S2,INTS12,MACROH2A1,RPS3,PPP1R10,BCCIP,EIF4H,FAF2,GFPT1,PPP2R1A,RPL29,RAF1,B3GNT2,RPS11,CTNNA2,EZH2,RPN1,CHMP4C,PCNA,ZC3H7A,RPS24,HSPD1,SRSF4,RFC3,RAD21,G3BP1,BCL7C,HNRNPA1,EIF3D,HMGA1,PRDX1,CLPX,IFIH1,HNRNPD,RPL23,RPLP1,RPLP2,RPL8,CBFB,PHB1,NTMT1,PPIA,NOP58,MPP1,ETF1,WDR77,KCND3,MFAP1,SLC25A3,ANXA7,VAPB,CRYAB,ATP5PO,LARP4B,JADE1,MCRIP2,COIL,G3BP2,MCMBP,GPC1,SRI,YTHDF1,RIOK2,MCM4,USP13,PYCR1,CUL3,HSP90AA1,RPS5,PFDN4,LSM14B,LMNB1,MYO6,SNRPD1,RPS9,FAU,EIF3K,PELO,CHCHD3,PRRC2A,USP5,CLIC4,TENT5C,RPL35,RBBP4,ACTB,LBR,RPL15,FBP1,YTHDF2,PPME1,PDLIM4,MAGEA4,RAB1A,FAF1,SFXN1,FBXO25,CTNND1,RPS13,RIGI,PTGES3,MSH6,EIF3E,CTNNBL1,HDAC6,ZMYND11,MOV10,SPATS2L,ATP5MG,CNN3,ESYT1,RPL12,SRPRA,ATP5PD,PPP1R18,SIPA1L1,COMMD3,RBMS2,EIF3J,RARS1,RPLP0,RPL26L1,CARHSP1,LMNA,JUP,CDK1,GRM2,METTL14,LSM2,GPX4,SQSTM1,TCEA1,RPA3,SIRT7,POLDIP2,FBXW7,RPL4,SMC4,ATP5F1A,USP14,DNAJC8,TUFM,RACGAP1,KPNA6,AR,CTSD,CSK,PYCR2,CDC73,MAPRE1,CHORDC1,RTRAF,PRKRA,GSK3A,RPS20,RPS12,CCNF,PELP1,EIF2AK2,SMAP2,CTTNBP2NL,VIRMA,RPL22,SEC63,NDN,TMOD3,MAGOHB,TXN,YES1 |
| 3.442e-18 | -40.21 | RPL5 (ribosomal protein L5) | protein interactions | 6125 | 574 | 257 | 19454 | 5460 |
EIF3D,MAP3K14,RPL23,RSBN1L,RPLP2,HP1BP3,RPLP1,MRTO4,PHB1,RPL9,RPL8,RPL7,NOP58,LGR4,RPL29,MAK16,OTUD6B,B3GNT2,RPS11,NGB,CHMP4C,EZH2,RPS24,ARGLU1,SLC25A5,RAD21,SSRP1,RPS27A,TRIM37,GNL1,G3BP1,TNF,RBBP7,UFM1,PDE4B,NOP16,CUL2,GRB10,CUL3,ACO2,RIT1,RPS5,HSP90AA1,BRCA1,DCAF4,SEC61B,RPS9,RPL37A,RSRC1,EIF3K,FAU,PRRC2A,RPL19,RPF1,RPL35,LARP4B,EMC9,NMRAL1,G3BP2,COIL,YTHDF1,NOP53,HDAC6,CD9,SPP1,PSMB1,RCHY1,SRPRA,SRP14,RPL12,MDM2,RPL35A,EXOSC8,RPL15,EEF1A1,SRP72,RNF181,ILF2,LLPH,RPL23A,TCOF1,NKRF,FAF1,EIF3E,RIGI,MRPL22,RPS13,VRK1,HUWE1,USP14,PPP1CC,RPL26,SAYSD1,RPS12,RPS20,PTEN,GSK3A,PRKRA,METAP2,POP7,TUBA1B,PELP1,CCNF,RPL22,RPL13A,ZNF622,NDN,CDK7,EIF3J,EDF1,ATG16L1,RPS14,HAUS2,RPL26L1,RPLP0,LMNA,MTDH,CLK1,SIRT7,RPA3,BRIX1,RPL4,FBXW7,HMGB1,NPM3,DDRGK1,XPO1,RPL6,WWP2,DRG1,AGR2,SRSF1,HSP90AB1,LYAR,FAM98A,RPS10,RPS7,EEF2,TUBA1A,DNAJC25,SOX2,MAGEB10,TRMT1L,RPL18,RPS23,SLC1A2,ZRANB2,SEC61G,PABPC1,TOP2B,RPL31,RPL28,RPS4X,KRAS,RPL39,BTF3,MYC,NSA2,RPS26,ICAM1,H1-10,FBXW11,FTSJ3,PRMT5,SURF2,CMTR1,RPL10,CBX5,RPL27A,MTF1,PIH1D1,NUFIP2,EIF4B,YAF2,HDAC5,HSPA8,RPS28,FAM50B,RFC4,SSR3,STAU1,EEF1G,TRA2B,UFL1,CSNK2A1,CD81,COPS5,PPM1D,PLEKHO1,ENY2,RPL10A,RPS2,RPL24,SNRNP70,TUBG1,RPL32,TMPO,DKC1,RPS27L,CAND1,RPS16,DNAJC1,ARL6IP5,RPSA,TP53,UBL4A,NUPR1,TAF2,HBP1,DNAJC2,RBM34,DHX9,ABCE1,RPL3,SNIP1,RPL17,MEPCE,SRPRB,MRPS33,H3C1,NEDD8,RPS17,SUB1,RPL7A,UBE2H,IGF2BP1,PDCD4,RC3H2,EIF3G,SPOP,MECP2,EIF2S2,RBMX2,SRP54,SEC61A1,CSNK2B,FGFBP1,ZNF330,PSPC1,RPS3,RPL10L,FGF13,CFTR,UBE2M,HEXIM1,SSR1,RPA2,RNF113A,PML,NLE1,BAP1,SNAPC1,RPL27,HSPA5,MARS1,EIF4E,RPS15 |
| 3.468e-18 | -40.20 | HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1) | protein interactions | 3181 | 633 | 278 | 19454 | 5460 |
MCPH1,SF3B4,ZMYM2,MIRLET7B,CMTR1,PAPSS2,ESR2,SNRNP40,ATP5F1B,MATR3,SNRPB,RPL39,BTF3,ZMAT3,HNRNPAB,PSMA4,HNRNPC,LDHB,MYC,YAE1,SERPINH1,ICAM1,FBXW11,CKB,EP300,DDX5,HSPA8,HDAC5,RPS28,SLU7,DDX39B,SNRPA,MRPS7,STAU1,ADRB2,UFL1,HNRNPA0,SRSF2,TRA2B,DUSP14,RPL27A,MTF1,PIH1D1,EIF4B,ACAA2,PPT1,MIR214,EED,HOMER3,FUBP3,SUMO2,MIR9-1,SNRPA1,HNRNPL,CTNNB1,DDRGK1,MIR29C,WWP2,MIR143,DCAF4L2,HSPB1,MIR140,DDX1,MGMT,MIR221,MIR31,AGR2,MIR206,EWSR1,PABPC1,RBM3,ABCF1,MIR9-2,HNRNPDL,MIR155,HNRNPF,DCP2,KRAS,EEF2,RPS7,SOX2,MIR222,ISG15,RHOBTB1,CSNK2B,PSMA6,PSPC1,RPS3,SMURF1,CHMP5,KCTD9,UBE2H,IGF2BP1,RC3H2,RNF113A,HNRNPH2,PGK1,BAP1,MIR10B,MIR29A,HSPA5,MIR107,MAEL,CFTR,CD2AP,NEK2,IGFBP3,MIR34B,MIR7-1,ACACA,HEXIM1,TFIP11,MIR21,UBE2M,ZNF326,RPA2,CD4,ARL4D,SSBP1,CD274,SYNCRIP,CDC5L,MIR429,RBM42,MIRLET7G,CAND1,FZR1,EDC3,API5,GAPDH,CD81,COPS5,CSNK2A1,DPP4,ENY2,H2AC4,SHC1,SNRNP70,MIR9-3,DHX9,ERO1A,MIR200A,MIR16-2,MEPCE,MIRLET7C,HNRNPK,NEDD8,PSMA5,H2AX,MTCH2,INSIG2,TP53,UBL4A,NUPR1,AP2M1,SNRPD1,RAN,SNRPB2,MIRLET7D,TENT5C,ACTB,SIAH1,MIR98,CUL3,CUL2,MIR363,BRCA1,PSMA3,NMRAL1,UNC45A,MIR106A,PYGB,PAFAH1B2,CDKN1A,PPP1CB,TIMM13,CCL21,MIR141,MIR7-2,PSMB4,PHB1,IFIT2,FOLR1,CSF2,PPIA,SRSF10,TRIM35,HNRNPA1,DPY30,MAP1S,PDIA3,HNRNPD,AHSA1,MRPS26,MIR1-1,BAG2,HSPD1,SSRP1,AP1M1,UBE2A,RPS27A,TRIM37,TNF,ACTN4,RAF1,B3GNT2,AP2S1,NME1,CTSA,GDI2,EZH2,MSN,UBASH3B,CCNF,MIR16-1,VIRMA,NDN,PPP1CC,DNAJC8,SEC13,AP2A1,MIR145,MIR34C,MTDH,SQSTM1,MIRLET7I,MIR205,PNO1,RPA3,AATF,FBXW7,MIR7-3,MIR1-2,EEF1E1,UBA52,SF3A1,ATG16L1,RPLP0,HNRNPH3,PICALM,GRM2,LSM2,METTL14,CHMP1A,LMNA,MIR25,PSMB1,AIFM1,MIR106B,CWC15,CDK9,TOP1,PRNP,EIF2B2,DCUN1D1,ATP1B1,HDAC6,GRSF1,FGR,MIR34A,CRBN,EMC2,HSD17B10,FAF1,SMN1,PTGES3,VRK1,CTNNBL1,EIF4EBP2,HUWE1,GGCT,MIR200C,MIR15A,MTA3,FBP1,ILF2,MIR17,MIR20A |
| 3.586e-18 | -40.17 | SQSTM1 (sequestosome 1) | protein interactions | 8878 | 984 | 399 | 19454 | 5460 |
SSBP1,MRPS9,SLC38A2,ELOC,SMG8,IL17F,BCL10,DHX9,MYD88,MAP1B,TGFBR2,NEDD8,EMILIN3,TP53,STRBP,KBTBD4,NUPR1,CAPZA2,PIK3CA,DYRK1A,MAP3K3,STAT5A,CCNB1,RAB2A,PSMB2,SLC25A1,TRIM32,ALKBH5,PDCD4,IGF2BP1,NIF3L1,PML,IRF3,BAP1,BNIP3L,RPS15,WDR82,HSP90AB1,CCT7,MITF,C1QTNF1,CTNNB1,YWHAH,XPO1,YWHAG,RAB5C,WWP2,ZCCHC10,IFI16,LAMP2,CNOT2,CBL,MYO1B,TRIM21,FBXO3,RAB18,DCP2,PELI1,EEF2,RPS7,TMEM59,TUBA1A,HGS,SMARCB1,PTRH2,TUBB4B,SMU1,DLST,LMBR1L,ESR2,POLR2B,TAX1BP1,TAGLN2,STAT1,BAG3,BTF3,SFN,HNRNPAB,MYC,RPS26,FIS1,PSMD14,CKB,CCT2,DDX5,TMEM160,PEBP1,PHB2,NDUFS2,GPC4,CSNK1A1,EIF4B,NLRP6,TES,SMAD3,RPL12,MRPS23,CDK9,CGAS,SEMA3C,TNFSF18,TP53INP1,SPATS2L,MOV10,OSBPL8,ID1,RAB1A,SMN1,RIGI,ABHD10,FARSA,TRIM63,CCT5,SERPINA1,NDUFS3,TRIM27,METAP2,TUBA1B,CCNF,GNAI2,VIRMA,SH3BGRL,UBB,TENT4A,RHOJ,RACGAP1,SMAD2,RTN4,GRIA2,RPA3,DVL2,UTP23,CHMP2B,FBXW7,PIK3R2,FTH1,GABARAPL2,UBA52,SYNGR2,AGAP1,KRT8,MAP1LC3A,PSMB4,PSMB5,SPRED2,PPIA,EGLN3,INA,IFIH1,ATG9A,PIK3R1,RB1CC1,MED4,MRPS26,MRPS11,BCKDK,HNRNPA2B1,SCYL2,SAR1B,PSMD12,GTF3C3,RPS27A,TNF,JUN,GABARAPL1,PPP2R1A,VDR,RAF1,BUD23,B3GNT2,SNRPE,IFT172,S100A6,GRIA1,PRRC2A,TENT5C,TUBB,ACTB,LGALS3,STARD7,PDLIM3,PRPF31,NLRP3,HSP90AA1,RPS5,BRCA1,YWHAZ,TRIM5,BIRC2,TXNL1,PXMP2,STXBP1,SLC25A3,HEXB,VAPB,CRYAB,MCL1,SYNCRIP,FIBIN,SLAIN2,TMPO,RPS16,CSNK2A1,EDEM1,FAM20C,BECN1,SMAD4,TUBG1,SOD3,MRPS18B,SLC25A11,NAE1,KPNA2,TOLLIP,CHDH,CAMKV,RPAP2,ACTR1A,RRM1,PSMC3,SESN2,TAB2,GFM2,CARD19,IK,NFE2L2,TFRC,TLR3,MRPS28,PSMC5,PSMA6,TRAF1,SRPK2,CSTF3,SMURF1,ADRM1,BUB3,MRPS21,RPS17,CEP85,MAT2A,TNFAIP3,ATP1A1,TRIM23,DNAJC10,SPOP,HFE,RNF113A,TWNK,HSPA5,ZC3H15,GREM2,KDM1A,CFTR,GABRA1,RETN,HECTD1,GSTP1,SAMM50,RPA2,SDCBP,SDC4,UQCRH,TCP1,PAIP1,NT5C2,IQSEC1,HSPB1,YWHAB,DRG1,FKBP4,AGR2,IKBKB,TRIM11,PABPC1,VDAC1,KRAS,CSTF2T,SOX2,TRAF2,ISG15,NUDT19,IRF8,PHF21A,TRIM44,ATP5F1B,PSMD4,HSPA8,RFC4,STAU1,SSR3,UBE2D3,HNRNPA0,CD59,FUNDC1,FHOD3,PAFAH1B1,KLHL3,SDC2,AIFM1,SRP14,SRPRA,CAV1,ATP5PD,HDAC6,BMPR1B,CALR,CRHBP,CRBN,SNAP23,NTRK2,SEPTIN7,SLC25A10,ARF4,CTNND1,SOCS2,SMAD1,MAP1LC3B,TBK1,SRP72,ILF2,JOSD1,ENC1,GSK3A,OPTN,STUB1,SLC25A4,LDHA,USP14,AR,ATP5F1A,GPX4,MTDH,MAVS,SQSTM1,CST11,GABARAP,HMGB1,USP8,SMC4,EIF5B,CNP,CCND1,EDDM3B,ATG16L1,PSMC4,OXSR1,CDK1,MRPS34,GJA1,PHB1,CETN2,CACYBP,ERLIN1,CCAR2,OCRL,ATG7,MARCHF5,PSMD3,LY6G5C,TRAF6,PSMD10,RPS24,TRIP4,RNF26,HS2ST1,TRIM37,TRIM26,RRAGB,G3BP1,RPL37A,GNB1,TNPO3,CHCHD3,OTUD7B,RHEB,TOMM40,CUL3,PYCARD,CUL2,NTRK3,PLN,MYO6,BLOC1S5,FAS,PMAIP1,HADHA,UPF3B,G3BP2,FTL,NRBF2,PSMC1,GPC1,IL1B,RAB6A,MTX2,WDR77,NDUFA5,PCLAF |
| 3.938e-18 | -40.08 | SNCA (synuclein alpha) | protein interactions | 6622 | 696 | 300 | 19454 | 5460 |
SRSF4,NRGN,GNL1,G3BP1,LASP1,PLCB1,HNRNPA2B1,ZYX,AP2S1,SART3,GTPBP1,VPS33A,VAMP2,WDR37,GFPT1,PPP2R1A,GABARAPL1,FAF2,SNCB,FEN1,CACYBP,PPIA,NDUFS8,RPL7,INA,HP1BP3,XPO5,SLC6A2,MAP1LC3A,TSG101,MYEF2,PPP3CA,BCL2L1,RPL23,HAX1,HNRNPD,TRAF6,SIAH2,EIF3D,HNRNPA1,HSPB8,PSMD3,TAF7,PRPF19,PRDX1,SKP1,SRI,GPM6A,ATAD1,RNF10,CDC42EP2,RABAC1,CRYAB,VAPB,PRDX3,IDH3B,FABP7,CLIC4,TNPO3,ABHD12,ACTB,SIAH1,LGALS3,TUBB,DYNLL1,AKR1C2,PRDX2,ARPP19,AP2M1,RAN,BAD,ARMT1,ILK,BAX,PFDN2,HSP90AA1,CGRRF1,YWHAZ,JPT1,CUL2,NDUFB6,MSH6,OLA1,CTNND1,CDC42SE1,VRK1,LSM4,CAMK2G,CTNNBL1,TAGLN3,HINT1,SLC6A3,NTRK2,ZC3H11A,SEPTIN7,ENC1,CD2BP2,EEF1A1,MAP1LC3B,CMPK1,CAV1,NCBP2,AKAP17A,TOP1,SRPRA,HACD3,FGR,OSBPL8,RAB3A,CNN3,ESYT1,GLO1,HDAC6,USP8,FBXW7,EIF5B,SQSTM1,RTN4,DVL2,SOD1,MACROH2A2,STAMBP,MEST,RARS1,PDIA2,P3H1,JUP,CNP,ARHGAP1,UBA52,SAP30BP,VIRMA,FERMT2,UBB,YES1,RPS12,MSN,UBE2I,GNPDA1,GTF2A1,CMBL,PRKRA,CTTN,TUBA1B,EIF2AK2,CTNNA1,CHRM5,PELP1,STUB1,MAPRE1,CDC73,NAPA,PEA15,NONO,GMPS,CSK,CTSD,PRPS1,RPS4X,RUVBL1,VDAC1,HNRNPF,DCP2,ARHGAP15,RUVBL2,MYO1B,ABCF1,SMARCB1,TPPP,MSX2,KIF2A,TUBA1A,RANBP1,PPIL3,ELK1,SNRPD3,RAB1B,EIF2S1,MAGED2,CORO1C,POLR2L,TNIK,SIN3A,DRG1,YWHAB,HSPB1,FKBP4,DRG2,CTNNB1,XPO1,YWHAH,RPL6,GSTM3,LAMP2,ADRB2,HNRNPA0,FXR2,RAB5A,HSPA8,PEBP1,CSNK1A1,KLC2,EIF4B,GSTM2,GPC4,SYK,APEX1,RPL10,SNRNP40,NDFIP1,STAT1,TAGLN2,SMU1,RRAS2,VDAC2,CDC42EP3,PRSS1,H1-1,ADK,CKB,KIAA1191,SNRPB,HNRNPC,HNRNPK,KPNA2,RAB3B,MRPS33,NUP107,H3C1,DHX9,MAP1B,NOSIP,PSMC3,CBX3,CHAMP1,DDX42,H2AX,CDK4,TMPO,ILVBL,MIF,RPS16,CDK6,PREP,UBE2N,STT3A,HCLS1,MAP4,RPL10A,TMOD2,RPS2,CDK12,NOS1AP,SMCHD1,TUBG1,POLB,GAPDH,EDC3,CSNK2A1,USP2,HSPA5,CLU,TOMM20,STK38,HSPB2,HNRNPH2,UGDH,SNCG,IDH2,RPA2,CDC42,HSPB6,UBE2W,SPTBN1,SRC,DYRK1A,PRKCE,CHMP5,EIF4H,MACROH2A1,PLCB2,GNAO1,KLK6,ATL1,RPS3,PSPC1,UQCRC2,CALU,IGF2BP1,BICD2,EIF3G,GLOD4,SLC6A4,DNAJC5,EXOC5,ARHGAP21,SUB1,SMARCA5,SLC25A1,AKT1 |
| 4.018e-18 | -40.06 | NFX1 (nuclear transcription factor, X-box binding 1) | protein interactions | 4799 | 448 | 211 | 19454 | 5460 |
DDX1,DRG1,RIOX2,RPL6,XPO1,RPS10,FAM98A,NOB1,EIF2S1,LYAR,SIN3A,SRSF1,RBM5,S100A8,PDHA1,MTA2,ZRANB2,RPL18,RPS23,TOP3B,PTS,RPS7,EEF2,PSMA1,HNRNPF,RUVBL1,RPL28,RPS4X,HNRNPDL,POLDIP3,RPL31,ABCF1,PABPC1,TRIM21,RUVBL2,CIRBP,CKB,PSMD14,H1-10,FTSJ3,ELAVL4,PSMA4,HNRNPAB,PSMD1,MATR3,PSMD4,PSMB6,ESR2,SMU1,MRPL13,MRPS18A,RPL27A,MRPL12,HNRNPA0,FXR2,STAU1,RANBP10,MRPS7,RFC4,XRCC5,RPS28,HSPA8,LCN1,DDX5,SNRNP70,RPL24,RPS2,USP15,RPL10A,KARS1,RPS16,SYNCRIP,ALYREF,UBE2N,IK,MRPL33,PSMC3,MRPL47,ACTR1A,PSMA5,KPNA2,RPL17,MAP1B,SLC25A11,RPL3,DHX9,EIF3G,BICD2,IGF2BP1,PSMB2,SUB1,RPL7A,CFL1,RPS17,CEP70,RPS3,PSPC1,SF3B6,PSMA6,EIF2S2,CSNK2B,RPA2,TRIM36,RPS15,MRPL41,ZC3H15,EIF4E,HSPA5,MARS1,RPL27,EXOSC4,MRPL18,CSTA,RB1CC1,HNRNPD,RPL23,PRPF19,HNRNPA1,EIF3D,RPL7,RPL9,RPL8,PSMB5,PHB1,RPN1,RPS11,SF3B5,SNRPE,GTPBP1,ZNF263,CSNK1E,RAF1,RPL29,G3BP1,GTF3C3,SRSF4,PSMD12,RFC2,SLC25A5,HSPD1,HNRNPA2B1,RPS24,YWHAZ,RPS5,CUL3,MRPL16,MCM3,RPS29,MRPL23,TAB1,RPL35,RBBP4,ERH,PRRC2A,EIF3K,SNRPD1,RMDN3,RPL37A,RPS9,USP39,LARP4B,ARCN1,SLC25A3,SKP1,PSMA3,EMG1,EIF5A2,PSMD7,MOV10,RPL35A,CDK9,SRP14,AIFM1,RPL12,ILF2,MRPL11,YTHDF2,CCT5,CD2BP2,DDX39A,EXOSC8,RPL15,RPS13,SNRPG,NKRF,RPL23A,ASCC1,IVNS1ABP,RPL26,PPP1CC,TXN,LDHA,RPL13A,RPL22,TUBA1B,TNFRSF1B,RTRAF,RPS12,RPS20,RPLP0,RARS1,PSMC4,RPS14,EEF1E1,PDHB,EIF5B,RPL4,FBXW7,MRPL20,PNO1,MTDH |
| 4.438e-18 | -39.96 | BTF3 (basic transcription factor 3) | protein interactions | 689 | 777 | 328 | 19454 | 5460 |
RPL23A,TCOF1,EHD4,PPP1R12A,SNRPG,RIGI,PTGES3,ARF4,RPS13,THRAP3,RPL15,GNG10,EEF1A1,MAP2K3,NDUFA2,MRPL11,MTA3,RNF181,ILF2,ACTR2,NAA30,RPL12,H2AZ1,TFE3,SRP14,TOMM70,PRNP,TOP1,RPL35A,GTF2E1,LAMTOR2,MED21,SLC2A1,ARPC2,SQSTM1,H2BC12,MYH2,PRIM2,RPA3,VPS28,NHP2,CHMP2B,RPL4,GTF2I,FTH1,SIPA1L1,MYL12B,SEC22B,ATG16L1,RPS14,RPLP0,STAMBP,HSP90B1,CHMP1A,LMNA,DCTN4,RPS20,RPS12,RTRAF,PRKRA,GSK3A,ENO1,EIF2AK2,GNAI2,RPL22,TECR,RPL13A,YES1,TMOD3,TXN,TUFM,NONO,ATP5F1A,RUNX1,RPL26,AP2A1,CDC73,LGALS8,RPS24,BAG2,SRSF7,HNRNPA2B1,MORC2,HSPD1,SLC25A5,RFC3,SSRP1,SAR1B,PSMD12,RPS27A,RBBP7,LASP1,G3BP1,PPP2R1A,RPL29,ACTN4,TMT1B,NAA15,RPS11,PRKAG1,RPLP1,RPLP2,KRT8,TSG101,RPL8,LILRB4,RPL9,CBFB,DHX15,CETN2,PPIA,CNTROB,RPL7,SPTAN1,KCTD10,NOP58,TRA2A,EIF3D,ZNF207,HNRNPA1,PRDX1,ATG9A,HMGA1,PDIA3,RPL23,VPS4A,MRPS26,PMAIP1,NUBP2,HADHA,ATP5MK,G3BP2,SKP1,CMAS,ZDHHC17,POLA2,PSMC1,HSCB,PPP1CB,H1-5,SLC25A3,MYL6,IFTAP,RPS9,SNRPD2,RPL37A,RAN,GNG12,RPL19,ERH,MAD2L1,RBBP4,DYNLL1,TUBB,RPL35,ACTB,PRDX2,MCM3,PROX1,RFC5,CUL3,GRB10,ILK,RIT1,HSP90AA1,RPS5,LMNB1,MYO6,YWHAZ,DHX9,RPL3,RAB13,SNIP1,MAP1B,RPL17,H2BC14,CAPZA1,PDRG1,TMEM33,HNRNPK,CHMP1B,H3C1,DYNC1I1,ACTR1A,H2AX,TP53,RPSA,KBTBD4,NAA35,CAPZA2,ARPC3,TFCP2,DSTN,RPL32,SSBP1,METAP1,SYNCRIP,DKC1,TMPO,RPS16,GAPDH,TPM3,LYPLAL1,RPL10A,RPS2,RPL24,SNRNP70,EXOSC4,LSM12,TWNK,BANF1,TMEM263,BAP1,CORO6,RPL27,HSPA5,TOMM20,OIP5,RBM22,RPS15,CDC42,SPTBN1,USE1,RPA2,VPS4B,H2BC11,SGTA,CSNK2B,LIG3,RPS3,SRPK2,CHMP5,BUB3,EIF4H,H2BC9,RPS17,CFL1,VAMP5,RPL7A,CARS1,UBE2H,CALU,PDCD4,IGF2BP1,MECP2,RTCB,MYO1B,RUVBL2,RINT1,PABPC1,RPL31,RWDD4,RPS4X,RPL28,RUVBL1,HNRNPF,KIF2A,EEF2,RPS7,TUBA1A,RANBP1,RPS23,MOB3C,RPL18,MTA2,TUBB4B,CORO1C,SRSF1,CHMP2A,HSP90AB1,SNRPD3,LYAR,EIF2S1,FAM98A,HNRNPL,RPS10,CTNNB1,DDRGK1,BTF3L4,YWHAH,PPFIBP1,YWHAG,RPL6,WWP2,IFI16,DDX50,HSPB1,YWHAB,DDX1,H2BC17,DR1,DDX5,HSPA8,SF3B1,XRCC5,SPECC1L,HIRA,EEF1G,STAU1,SRSF2,FXR2,TRA2B,CD59,SYK,RPL27A,ACAA2,MRPL13,EFHD2,DLST,ESR2,RPL10,POLR2B,TAX1BP1,TRIM29,MATR3,DRAP1,SNRPB,BTF3,HNRNPC,MYC,SERPINH1,PRSS1,RPS26,PDF,COP1,MRPS25,H2AZ2,CHTOP |
| 4.908e-18 | -39.86 | ABCE1 (ATP binding cassette subfamily E member 1) | protein interactions | 6059 | 379 | 185 | 19454 | 5460 |
EIF3G,CISD1,UBE2H,SMARCA5,RALA,CTSB,GMDS,SUCLG2,DYRK1A,SRC,PSPC1,RPRD1B,RPA2,CDC42,AIF1L,TOMM20,BCL6,MAIP1,DDX46,EXOSC4,MAP4,KARS1,DPP4,CSNK2A1,ELOC,RPS16,RBM42,TMPO,DKC1,SDHB,CD274,RPL32,RAC2,CBX3,SURF4,FURIN,TP53,PSMA5,MAP1B,ABCE1,PSMD14,YAE1,POLR1B,MYC,PSMD1,PSMD4,TIMM21,CBX5,APEX1,RABIF,VDAC2,ANAPC2,PSMB3,CD59,UFL1,PRCP,STAU1,GNB4,PEBP1,RFC4,XRCC5,HSPA8,EP300,AKAP1,AK2,AGR2,DDX1,XPO1,YWHAH,CTNNB1,RHOH,PEG10,RAB35,FUBP3,CORO1C,PLS3,PDHA1,GNAZ,GNAQ,SOX2,KRAS,PSMA2,DCP2,RPS4X,GNA11,ABCF1,LTO1,EWSR1,RTCB,MAPRE1,CIAO1,PPP1CC,PNP,RHOJ,SLC25A4,TECR,RPL22,VIRMA,CCNF,METAP2,EIF4A3,RTRAF,RPS12,ACAT1,RPS20,MSN,JUP,TIMM23,LMNA,METTL14,ATG16L1,SF3A1,CCND1,EIF3J,SMC4,RPL4,RHOU,RPA3,PPM1G,SIRT7,CSTB,DNAJC7,ISYNA1,HM13,RPL35A,CGAS,HRAS,AIFM1,SRP72,MAP1LC3B,HSPE1,PTGES3,RNASEL,EIF3E,GNG5,CCNY,SNAP23,MYO6,LMNB1,CNIH4,PFDN2,CBR3,RIT1,ILK,CUL3,RPS29,TSN,DYNLL1,NDUFAF4,GNB1,RPL19,MED23,VAPB,HEXB,NDUFA5,WDR77,RND2,PPP1CB,ETF1,DUSP22,HSCB,RP2,SRM,PYGB,G3BP2,RHOG,HAX1,PDIA3,ATG9A,EIF3D,ZNF207,RAP2B,ATXN10,KCTD10,RPL7,EGLN3,ATP6V1A,EZH2,CTSA,RPS11,POLR2C,RBBP7,S100A10,FLOT1,NDUFA4 |
| 4.931e-18 | -39.85 | INS (insulin) | protein interactions | 3630 | 517 | 236 | 19454 | 5460 |
SKP1,DNAJC3,ATP5MK,TXNL1,CRYAB,ATP5PO,LARP4B,MYL6,NDUFA5,SLC25A3,RRAGA,PPP1CB,IDH3B,TIMM29,PRDX2,ABHD12,CHP1,PRRC2A,RAN,RPL37A,RPS9,SEC61B,MYO6,YWHAZ,DHRS1,RPS5,GRB10,SAMHD1,MRPL16,GNL1,FOXP4,CHST10,ZYX,NDUFA4,HINT2,MRPS11,NDUFS6,RPS11,CPE,FAF2,GFPT1,PPP2R1A,RPL29,MMAA,WDR37,RPL7,AGK,PXYLP1,PPIA,RPL8,RPL9,RPLP1,RPLP2,DDX23,RHOG,HNRNPD,TMEM30A,VPS4A,RPL23,PRDX1,GTF2I,TTR,HMGB1,RPL4,CSTB,PNO1,FADS2,MRPS34,DCTN4,HSP90B1,CARHSP1,RPS14,RABL3,UBA52,CCN3,CNP,TXN,SLC25A4,TECR,UQCRQ,DEK,RPL22,EIF2AK2,GANAB,GAS2,RPS20,PTEN,RPS12,SDF2L1,ARFGAP3,GGCX,DNAJC19,CTSD,TUFM,NONO,HUWE1,FARSA,TUSC3,VTA1,RPS13,PRDX4,NSDHL,SFXN1,RPL23A,HINT1,IGF1R,SLC25A20,DHRS7B,TMEM126A,COMTD1,CCDC47,NDUFA2,MRPL11,EEF1A1,RPL15,MAPRE2,TOP1,SEMA3C,G6PD,RPL12,SRP14,SCG5,RB1,GMPPA,TMEM177,HNRNPA0,RPS28,NUDT2,HSPA8,RAB5A,DDX5,PALS2,EIF4B,NUFIP2,CSNK1A1,SYK,RPL27A,EHHADH,CYP27A1,TAGLN2,PSMD4,TAMM41,POLR2B,PAPSS2,TACO1,CIRBP,OSGEP,RPS26,CMC1,CRMP1,HNRNPC,USP30,RPS4X,RPL28,RPL31,ABCF1,MYO1B,EWSR1,CDK5,TPPP,PTRH2,PDHA1,NDUFA12,RPS23,TRMT1L,ETFB,CRTC2,KIF2A,RPS7,HNRNPL,UQCRH,GLRX,MAGED2,HSPB1,INPP4A,RPL6,NDUFV2,RPS15,MRPL41,ZC3H15,HSPA5,CLU,RPL27,TRIM3,TXNDC17,PRDX6,IDH2,CYC1,PPP1R8,CDC42,NTPCR,CTSB,ADRM1,CHMP5,IDE,ROMO1,SRC,PSPC1,RPS3,LIG3,EIF2S2,DNAJC10,ATP1A1,CDKN2AIP,SORD,ALKBH5,SLC25A1,MAT2A,RPL7A,RPS17,TMEM33,RPL17,CTSC,MYD88,NOSIP,PALM2AKAP2,RPL3,RAB13,CAPZA2,MRPL33,SLC25A24,PREB,RPSA,RPS16,CPNE1,MIF,RPS27L,MRPS9,RPL32,NDUFB4,TDRD7,RPL24,RPS2,ATP6V1D,ACOT8,PRSS12 |
| 5.359e-18 | -39.77 | ACE2 (angiotensin converting enzyme 2) | protein interactions | 59272 | 986 | 399 | 19454 | 5460 |
STUB1,EIF4A3,GANAB,ACAT1,RPS20,MAGOHB,SLC25A4,SNX3,RPL13A,TECR,RPL22,CSK,ATP5F1A,GMPS,TUFM,XPOT,PNO1,MTDH,NPM3,GTF2I,RPL4,RPS14,SNRPN,CNP,CDK1,LMNA,JUP,HSP90B1,RPLP0,NOL7,H2AZ1,HACD3,CDCA3,SEC23A,ALCAM,CD151,PRNP,TOP1,G6PD,ISYNA1,MPG,SLC2A1,EXOC2,PSMD7,NSDHL,PC,HSD17B10,THRAP3,RPS13,GALNT2,MSH6,MDC1,YTHDF2,EEF1A1,HINT3,GGCT,RPL15,ILF2,SRP72,FAU,RAN,CYB5R3,AP2M1,RPL37A,MB21D2,RBBP4,RPL35,TSN,CHCHD3,RPL19,SAMHD1,MCM8,MYO6,LMNB1,THOC3,ATP5MK,CRY1,HADHA,GPC1,G3BP2,PPP1CB,RAB6A,ATP5PO,MYL6,PHB1,XPO5,RPLP1,OCRL,NOP58,RPL7,SPTAN1,RAB11B,PSMD3,PRPF19,PRDX1,STOML2,TRA2A,EIF3D,LYZ,RPL23,NDUFA4,ERP29,RPS24,G3BP1,ETFA,MCM6,AP1M1,ANP32B,FEN1,NUP153,TULP3,MOXD1,RPS3,LIG3,EIF2S2,PSMC5,MAT2A,NAA50,RPF2,SUB1,RPS17,EIF3G,ATP1A1,UGDH,BANF1,PRDX6,GHRL,KDM1A,ZC3H15,HSPA5,MARS1,SPTBN1,SUMO1,H2BC11,RPA2,ZNF326,IDH2,UBE2M,AVPR1B,EEF1B2,STT3A,RPS16,RBM42,TMPO,DKC1,KARS1,CAMP,RPS2,RPL10A,SLC25A11,RPL3,SLC16A1,CDC40,SRPRB,KPNA2,TOLLIP,TMEM33,H2BC14,SNAP29,IPO8,H2AX,TFRC,NHERF1,DNAJC2,RBM34,ARPC3,ZNHIT6,ATP5F1B,H1-10,CHTOP,PRSS1,GTPBP2,SNRPA,XRCC5,HSPA8,HNRNPA0,STAU1,RPL27A,CD59,CTBP1,PLAA,PTK7,FABP5,SRSF1,S100A8,EIF2S1,TCP1,LANCL1,GSTM3,DIRAS2,YWHAB,DRG1,TOP2B,CCT8,PABPC1,RUVBL2,SEC11A,PDIA6,RTCB,VDAC1,RPL28,POLDIP3,KIF2A,NUDT19,ZRANB2,MTA2,RPL18,AAMP,CRKL,TUBA1B,ENO1,ALB,DEK,GNAI2,NRP1,AP2A1,TCEA1,YKT6,NF2,SEC22B,ARHGAP1,UBA52,PICALM,RARS1,HNRNPH3,RPL26L1,HRAS,RPL12,LDLR,RPL35A,NCBP2,MDM2,MRPS23,RAB1A,SFXN1,NKRF,TCOF1,RPL23A,NOC4L,PTGES3,CMPK1,TM4SF1,SNRPD1,RPS9,EIF4A2,STARD7,ACTB,TUBB,RAB11A,F2,MRPL16,YWHAZ,RPS5,HSP90AA1,CYFIP2,YTHDF1,SRM,CDSN,AZGP1,NOTCH2,PGRMC1,ARCN1,SLC25A3,RPL9,RPL8,MRTO4,RPLP2,SNX17,AGK,PPIA,WDR44,PDIA3,HMGA1,HNRNPA1,HNRNPD,COTL1,SLC25A5,HNRNPA2B1,MKLN1,SRSF7,DHX16,RPS27A,SSRP1,ENKD1,ANP32A,ACTN4,RPL29,PPP2R1A,FAF2,ERLIN2,RPN1,RPS11,STX12,SART3,UQCRC2,CCSER2,SRP54,CALML5,SEC61A1,CSNK2B,MACROH2A1,SLC25A1,RPL7A,CFL1,GORASP2,ATP1B3,DTL,IGF2BP1,SORD,RPL27,DDX46,TXNDC17,PGK1,ZBED3,DLAT,WDR3,SSR1,LUC7L3,RPL32,RAP1B,SLC39A10,DSTN,CDK6,KCTD3,MYL12A,ESD,TSPO,PPIL4,GAPDH,RPL24,H2AC4,DHX9,PSMA5,H3C1,HNRNPK,CSE1L,RDH11,RPL17,TP53,RPSA,GNAI3,VDAC2,SMU1,PRMT5,RRAS2,TAGLN2,MATR3,CBX5,RPL10,CREBBP,HNRNPC,LDHB,PSMD1,CCT2,CKB,RPS26,SERPINH1,DDX39B,RPS28,SF3B1,DDX5,PHB2,EEF1G,EFHD1,ZC3H14,MMP14,GTF2IRD1,NUFIP2,RAB35,FUBP3,RAB1B,HNRNPL,RPS10,SNRPD3,SUMO2,CCT7,HSP90AB1,BAZ1B,RPL6,RAB5C,XPO1,NGDN,DDX1,RPL31,TRIM21,EWSR1,MYO1B,HNRNPF,RUVBL1,RPS4X,PRPS1,TRMT1L,ETFB,TUBA1A,RPS7,EEF2,TUBB4B,PDHA1,RPS23 |
| 5.366e-18 | -39.77 | H4C1 (H4 clustered histone 1) | protein interactions | 8359 | 1678 | 626 | 19454 | 5460 |
STAU1,SSR3,HNRNPA0,SAP18,XRCC5,FOS,RFC4,SNRPA,HIRA,YAF2,EP300,HSPA8,FKBP14,PIH1D1,NCOA5,SHMT1,RPL27A,NUP62,YIPF5,SNRNP40,TRIM29,ATP5F1B,PHF12,PHF21A,ANAPC2,SF3B4,CHTOP,H1-10,FTSJ3,RBM27,THOC6,BRMS1,THAP7,HMGN4,H1-6,ZNF609,POLDIP3,PAX6,HNRNPDL,CDCA7L,RPL28,PABPC1,RBM3,TOP2B,RTCB,FBXO11,RUVBL2,SMNDC1,NFKBIL1,RPL18,MTA2,SUPT5H,MED9,MAX,TNPO2,DYNC1I2,LYAR,LSM5,MEAF6,HMG20A,UQCRH,POLR2L,SRSF1,EED,RFX5,FOSL2,YWHAB,HSPB1,RBM22,KDM1A,HSPA5,HCFC2,BANF1,HNRNPH2,EXOSC4,ZNF326,RPRD1B,H2BC11,RPA2,SDCBP,UTP15,HEXIM1,E2F6,SUMO1,ING5,SPTBN1,NEK2,GTF3C4,SNRNP27,TRAM1,BUB3,TFEB,PPP1R10,LIG3,UBN1,CREB1,QSER1,ING2,TRIM23,LSM6,SPOP,RRP7A,ATP1A1,SUB1,MORF4L1,ANAPC15,RPS17,H2BC9,SRPRB,KPNA2,TMEM33,CDC40,H2BC14,ATP5PF,SNIP1,RPL3,NFE2L2,NECAP1,IK,TFCP2,CHAMP1,RNF8,PREB,SRFBP1,ZNHIT1,ZMYM4,ZMYM3,H2AX,SHPRH,DNAJC1,SURF6,CDC5L,TMPO,RBM42,DKC1,ILVBL,SYNCRIP,FA2H,CEBPG,SNRNP70,POLB,TUBG1,NAIF1,SMAD4,RPL10A,USP15,RPS2,RBM17,KARS1,TMA16,COPS5,NFIL3,SKP1,COIL,ZBTB39,WBP2,THOC3,HADHA,CCDC86,TTC1,NUP50,ADNP,ATP5PO,APOBEC3C,MYL6,NDUFA5,H1-5,TIMM13,PRDX3,SUPT3H,PPP1CB,DYNLL1,RPL7L1,RFXAP,RPL35,RBBP4,SNRPB2,RPL19,PARP2,RAN,RNF208,FAU,CPSF1,LMNB1,SP1,CUL2,NOP16,CUL3,MCM3,RBM15B,MCM4,RNF40,RFC5,ZNF668,TRIM37,ZBTB14,CBX7,RBBP7,PCGF6,RFC2,ANP32B,RFC3,MCM6,SRSF4,ATF3,ARGLU1,TRIP4,SRSF8,JRKL,INO80C,EZH2,RBPJ,SF3B5,SAP30,NUP153,GFPT1,BUD31,SPTAN1,RPL7,NOP58,CETN2,LRWD1,NDUFS8,PHB1,DNM2,SP2,THOC2,COPS2,RPLP1,HP1BP3,KDM2A,DDX23,RPL23,DPY30,PRPF19,TAF7,ZBED4,TRA2A,NUCKS1,SMC4,HMGB1,RPL4,NPM3,GTF2I,CERS2,SGF29,TMEM209,AATF,MBD3,NHP2,PRPF4,SIRT7,H2BC12,MTDH,LSM2,H2AC7,HSP90B1,TOX4,LMNA,CDK1,MACROH2A2,NOL7,SNRPN,EEF1E1,SAP30BP,RBFOX2,RPS14,CPSF4,ELP3,SLC25A4,RPL13A,MAGOHB,RPL22,TECR,EIF4A3,PELP1,TRIM24,UBE2I,RPS20,GSK3A,RTRAF,TADA3,PPTC7,CDC16,NDUFB10,AR,NONO,PPP1CC,USP14,RUNX1,ATP5F1A,BACH1,THRAP3,LSM4,EIF3E,SNRPG,MDC1,VWF,RNF20,RPS13,H2AC25,TFPT,PC,ZC3H11A,RING1,SEPTIN7,DMAP1,SAP30L,SRP72,RAD23B,ILF2,TBK1,UBR7,RPL15,THAP1,ING1,LBR,TOP1,POLR2I,NOP9,ATP5PD,POLE3,UBP1,RCHY1,H2AZ1,SRP14,SRPRA,CTDSPL2,SEC23A,EXOC2,EPOP,TOPBP1,CALR,ORC5,EI24,MPG,ZMYND11,TRA2B,SRSF2,GOSR1,UFL1,RPS28,DDX39B,DDX5,DR1,TAPBP,SF3B1,GTF2IRD1,TRMT112,EIF4B,ZC3H14,MTF1,ZCCHC7,MATR3,ESR2,RPL10,CBX5,LRIF1,POLR2B,CMTR1,MIDEAS,MCPH1,ZMYM2,SMU1,PRMT5,INTS10,H2AZ2,CCT2,H1-1,CXXC5,HNRNPC,HNRNPAB,CREBBP,MYC,CPSF2,KANSL3,RMI2,BTF3,RUVBL1,HNRNPF,CBLL1,CCAR1,RPS4X,RPL31,EWSR1,PTRH2,TUBB4B,APTX,RPS23,TAF10,SMARCB1,DHX38,RPS7,TUBA1A,SNRPA1,SUMO3,SNRPD3,OSBP,MITF,HNRNPL,RPS10,ISG20L2,ZNF740,FUBP3,RBM5,SIN3A,WDR82,NCK1,H2BC17,MAGOH,CDC23,MGMT,CBL,DDX1,RPL6,WWP2,CDC26,DDX50,BAZ1B,IFI16,DDRGK1,NGDN,CTNNB1,DNTTIP1,XPO1,WDR3,HDAC3,PML,NBN,DDX46,RPL27,BAP1,ARFIP1,DERL1,KLF4,LUC7L3,LEMD3,TFIP11,SUPT7L,MAFG,IGFBP3,DYRK1A,RSL24D1,MACROH2A1,INTS12,RBMX2,CHRAC1,MECP2,RBM7,EXOSC1,RPL7A,VAMP5,SMARCA5,CARS1,ARL6IP6,HNRNPK,CSE1L,ATP1A2,NUP107,H3C1,RPL17,PHF1,MEPCE,BHLHE40,MAP1B,DHX9,CBX3,EXOC3,DDX42,NUPR1,TP53,MIF,BRMS1L,CAND1,MXI1,MBD5,KMT5B,ALYREF,RPL32,SSBP1,GATAD1,H2AC4,RPL24,SMCHD1,MED29,LSM3,TAF9,COX5A,USP3,ENY2,ELOC,E4F1,CMAS,ZFP64,JADE1,USP39,VAPB,SLC25A3,MFAP1,ELOVL1,ACTL6A,RFXANK,ACTB,TUBB,MED17,REEP4,ERH,RSRC1,VPS72,SEC61B,POLR2F,SNRPD1,SNRPD2,YWHAZ,BRCA1,MED10,FYTTD1,RMI1,SETD7,RPS5,ATF1,PRPF31,SMARCE1,ASF1A,ATP5F1D,AHCYL1,MSL2,RAD21,SSRP1,RPS27A,GTF3C3,HNRNPA2B1,SLC25A5,ZYX,HSPD1,SRSF7,BAG2,PCNA,EXOSC3,NDUFS6,RPN1,SNRPE,RPS11,POLR2D,POLR2C,MACO1,ANP32A,RPL29,PPP2R1A,JUN,TMEM237,DHX15,G2E3,SRSF10,RPL8,KRT8,RPLP2,VCPIP1,MED4,HNRNPD,INO80E,BABAM1,HMGA1,HNRNPA1,FBXW7,BRIX1,CXXC1,ZNF319,HELLS,RPA3,PPM1G,PPIH,SPCS2,ANAPC16,STOM,WTAP,HNRNPH3,SEC22B,UBA52,RABL3,SF3A1,COPE,ZBTB17,NDN,DEK,JUNB,VIRMA,SCML2,CCNF,RPS12,TRIM27,PPIG,DNAJC19,CDC73,AP2A1,ZNF687,TAF5L,RACGAP1,RPL26,VRK1,ZSCAN5A,SMN1,PAGR1,PQBP1,NKRF,TCOF1,FAF1,RPL23A,LLPH,FBP1,TIMM8A,CD2BP2,THOC1,RPL35A,CWC15,NCBP2,CDK9,TFE3,RPL12,TIMM8B,LDLR,MYBL2,EID1,EMX2,BRD3,H2AC14 |
| 5.462e-18 | -39.75 | MATR3 (matrin 3) | protein interactions | 9782 | 615 | 271 | 19454 | 5460 |
TRAF1,SRPK2,KCTD9,MACROH2A1,FKBPL,ELAVL2,ATP1A1,IGF2BP1,RBM7,RRP7A,UBE2H,CDKN2AIP,RC3H2,PRKACB,GSTK1,SUB1,RPL7A,HSPA5,MIR107,MIR29A,RASD1,HNRNPH2,RNF113A,MIR10B,BAP1,RPL27,MIR21,HEXIM1,MIR7-1,ACACA,RPA2,ZNF326,WWP1,AGO1,CDC42,MIR34B,TMPO,MIR429,CDC5L,FZR1,CAND1,MIRLET7G,SYNCRIP,ALYREF,RPS2,AKAP8L,USP15,RPL10A,SNRNP70,SMCHD1,COPS5,MIRLET7C,MEPCE,MIR16-2,NEDD8,HNRNPK,KPNA2,RPL3,MIR9-3,DHX9,MIR200A,SNIP1,NUPR1,SGIP1,DISC1,H2AX,ACTR1A,ZMYM4,KBTBD4,TP53,INSIG2,APEX1,RPL10,MATR3,PCMTD1,SMU1,MIRLET7B,PRMT5,CMTR1,DNAJB6,FBXW11,H2AZ2,BTF3,MYC,APOBEC3B,HNRNPC,SFN,SAP18,HNRNPA0,B9D2,UFL1,EEF1G,STAU1,HSPA8,SF3B1,DDX5,EP300,STK26,SNRPA,DDX39B,XRCC5,PIH1D1,NCOA5,MTF1,PABPC5,DUSP14,HNRNPL,MIR9-1,EED,MIR214,SRSF1,FUBP3,MIR221,DDX1,YWHAB,MAGOH,MIR140,HSPB1,AGR2,MIR31,YWHAG,YWHAH,CPEB1,MIR29C,DDRGK1,CTNNB1,IFI16,MIR143,WWP2,RPL6,RPL28,RPS4X,HNRNPDL,KRAS,HNRNPF,MIR155,RUVBL1,EWSR1,MIR206,RUVBL2,ACTR1B,RTCB,MIR9-2,ABCF1,RBM3,PABPC1,RPL18,ISG15,SOX2,MIR222,VIRMA,COPE,NDN,RPL13A,GANAB,RTRAF,UBE2I,PTEN,TRIM24,MIR16-1,CCNF,EIF4A3,CTTN,STK24,MIR145,FBXO7,ATP5F1A,NONO,AR,PIAS1,AATF,GTF2I,SMC4,RPL4,MIR7-3,FBXW7,MIRLET7I,MIR34C,RPA3,MIR205,ZKSCAN1,RPL26L1,HNRNPH3,LMNA,CDK1,METTL14,GRM2,MIR1-2,FTH1,RBFOX2,ATG16L1,CDK9,PRNP,TOP1,PRR3,MIR25,MIR106B,RCHY1,MIR34A,CRBN,HDAC6,CALR,MOV10,RPS13,CTNND1,MSH6,RIGI,THRAP3,VRK1,SNAP23,ILF2,MIR20A,MIR17,MIR200C,MIR15A,EEF1A1,MAP1LC3B,RPL15,FBP1,MIRLET7D,TUBB,POLR3B,SNRPD2,RPS9,MIR363,BRCA1,ZNF668,MIR98,RBM15B,MCM4,CUL2,PKP4,CUL3,MIR106A,CRY1,ARCN1,EMC9,TIMM13,PPP1CB,ALKBH3,NUP35,DHX15,RPL7,CCAR2,MAP1LC3A,MIR141,RPL8,MYEF2,IFIT2,MIR7-2,PHB1,MIR1-1,HNRNPD,DDX23,TRAF6,HNRNPA1,EIF3D,STOML2,DPY30,MCM6,SSRP1,EMC8,G3BP1,SRSF7,HNRNPA2B1,RPS11,EZH2,CHMP4C,LGR4,NAA15,RAF1 |
| 5.558e-18 | -39.73 | STAU1 (staufen double-stranded RNA binding protein 1) | protein interactions | 6780 | 1520 | 575 | 19454 | 5460 |
WDR3,SMG5,BAP1,RPL27,NLE1,PML,NBN,KLF4,HBB,CDC42,POLR1D,AGO1,CD2AP,GTF2H4,CDC20,EIF4H,CHMP5,SRP54,FGFBP1,CSNK2B,SEC61A1,MACROH2A1,PSPC1,UQCRC2,CCSER2,CDIPT,OAT,IGF2BP1,EXOSC1,UBE2H,AP3S2,BICD2,PHKA1,SMARCA5,CARS1,RPL7A,CCNB1,MEPCE,RPL17,PDE12,AKAP12,H3C1,HNRNPK,RAB3B,CSE1L,CLPB,DHX9,MAP1B,BIRC5,SURF4,STRBP,IMP3,KIF1C,RPSA,FZR1,CAND1,RPS27L,ADD1,MRPS9,ALYREF,RPL32,NOL12,MAP4,RPL24,SMCHD1,PPIL4,GAPDH,EDC3,API5,PLEKHO1,LYPLA2,FXR2,UFL1,PHB2,EEF1G,SF3B1,DDX5,DDX39B,CCDC9B,SPECC1L,NUFIP2,EIF4B,BET1,ZC3H14,POLR2B,NCKAP1,RPL10,ESR2,STAT1,MATR3,TAGLN2,CMTR1,H1-1,RCL1,SERPINH1,CCT2,ZMAT3,PSMD1,BTF3,SNRPB,MYC,HNRNPC,LDHB,HNRNPAB,CCAR1,RPS4X,HNRNPF,ROCK2,RUVBL1,RPL31,RPS23,PLS3,TUBA1A,H1-3,MAGEB10,ETFB,DHX38,GCLC,RPS10,NOB1,NXT1,WDR82,FUBP3,SWAP70,POU5F1,DDX1,ARMC8,XPO1,CPEB1,DDRGK1,BTF3L4,EXOC1,NGDN,CTNNB1,DDX50,IFI16,BAZ1B,PTDSS1,RPL6,RAB5C,WWP2,CHMP2B,BRIX1,UTP23,PDHB,NF2,KIN,TCEA1,RTN4,HELLS,RPA3,IDH3A,HNRNPH3,RARS1,RPL26L1,HAUS2,UQCRC1,KLF12,SYNRG,PIP5K1A,ARHGAP1,SCML2,FERMT2,DEK,PDCD5,TRIM27,RPS12,CCNF,METAP2,CTTN,EIF2AK2,ENO1,MAPRE1,ASCC1,RPL26,RACGAP1,TAF5L,FASTKD5,HUWE1,NOC4L,NSMCE3,FARSA,RPL23A,PPP1R12A,PQBP1,SFXN1,NKRF,ACTR2,CD2BP2,TAF1D,MAP2K3,AURKAIP1,EXOSC8,CCT5,TOMM70,CDK9,RPL35A,THOC1,NAA30,RPL12,EIF4E2,KRR1,ACTA2,CNN3,SMG9,TRPC1,SPP1,ERCC3,GRSF1,MOV10,SPATS2L,ATP5MG,CYFIP2,YTHDF1,EMG1,ARCN1,SLC25A3,USP39,LARP4B,EMC9,MYH1,GKAP1,RRAGA,PRRC2A,ACTB,TUBB,RPF1,SNRPD1,SNRPD2,ZMAT2,POLR2F,RPS9,TRMT6,PFDN2,SCFD1,LSM14B,YWHAZ,BRCA1,DCAF4,PRPF31,JPT1,NIBAN2,RAB11A,RPS27A,SACM1L,SRSF7,SLC25A5,ZYX,HSPD1,NUDT5,HNRNPA2B1,FGF3,RPS11,JPT2,RPN1,EXOSC3,RPL29,PPP2R1A,OTUD6B,ERLIN2,B3GNT2,RAF1,SRSF10,DHX15,STK3,INA,SNX18,RPLP2,BRD9,ATP6V1A,RPL9,RPL8,KLHL7,MRTO4,HNRNPD,COTL1,LHX2,PDAP1,DICER1,WDR12,HNRNPA1,ZNF207,HMGA1,INO80E,ZC3H15,EIF4E,HSPA5,MARS1,RBM22,EXOSC4,HNRNPH2,PRDX6,RAB9A,RNF113A,UGDH,SCLT1,GIT2,UTP15,HEXIM1,ACACA,RPA2,CFTR,FGF13,CAPN1,PPP1R10,CSTF3,SRPK2,BUB3,PPAT,EIF2S2,RPS3,ZNF330,ZBTB38,ATP1A1,RC3H2,RPS17,RPF2,CEP85,PTPN11,CAPZA1,DYNC1I1,CDC40,SRPRB,IMP4,KPNA2,TMEM33,ABCE1,SLC16A1,RPL3,NOSIP,SLC25A11,TAF2,TFRC,TFCP2,GPD2,NECAP1,DNAJC2,RBM34,IK,H2AX,DUSP1,RBM42,DKC1,SURF6,CDC5L,RPS16,GRM1,SYNCRIP,RPS2,RPL10A,SNRNP70,NOS1AP,COPS5,KARS1,CENPP,ZNF24,PGAM1,RBM17,UBE2D3,HNRNPA0,STAU1,HSPA8,EP300,HIRA,SNRPA,PYM1,XRCC5,PAK2,RPL27A,PABPC5,USP16,ATP5F1B,PSMD6,SF3B4,EFHD2,SLC38A1,ELAVL4,THOC6,POLR1B,RBM27,FTSJ3,PCCB,RPL28,HNRNPDL,ZNF609,HMGN4,FBXO11,RPAP3,RUVBL2,RTCB,KLHL23,PABPC1,CCT8,TOP2B,MTA2,RPL18,CRKL,NUDT19,CAAP1,ISG15,TRAF2,SOX2,KIF2A,TOP3B,FAM98A,EIF2S1,DYNC1I2,LYAR,TRIR,TCP1,MAGED2,SRSF1,POLR2L,DRG1,AGR2,CNOT8,PPIB,DIS3L,UTP6,TAX1BP3,RIOX2,MBD3,AATF,DGCR8,EIF5B,NPM3,GTF2I,SMC4,RPL4,SQSTM1,ARPC2,MTDH,SIRT7,ZNF574,OXSR1,RPLP0,NOL7,LMNA,CDK1,HSP90B1,EDF1,CNP,RBMS2,RPS14,WDR83,MYL12B,TECR,RPL22,ZNF622,LDHA,RPL13A,PRKRA,GANAB,ACAT1,TRIM24,EIF4A3,SMAP2,XPOT,EPHA2,PEA15,CASC3,TADA3,IVNS1ABP,ATP5F1A,NONO,PPP1CC,CDC16,RPS13,RNF20,ARF4,CTNND1,OLA1,EIF3E,MDC1,CAMK2G,CTNNBL1,THRAP3,WASL,HSD17B10,ILF2,SRP72,NECAP2,EEF1A1,RPL15,CCDC47,TBK1,YTHDF2,ZBTB2,G6PD,NOP9,ARF6,EIF2B5,TOP1,SEC23A,PWP2,SRPRA,HACD3,SRP14,AIFM1,DNAJC7,SLC2A1,MPHOSPH10,ESYT1,LRRC40,PSMC1,SKP1,UNC45A,G3BP2,NSFL1C,MCMBP,CCDC86,HADHA,MCRIP2,UPF3B,GTF2H5,ATP5PO,MED23,APOBEC3C,ADNP,NRDE2,WDR77,H1-5,RPL19,RPL35,RPL7L1,AP2M1,RPL37A,ARF1,CPSF1,RAN,BLVRA,MYO6,PLEKHJ1,LMNB1,ZNF668,MCM3,MCM4,NOP16,RRN3,CUL3,SRSF4,MCM6,PCGF6,G3BP1,LASP1,TRIM37,ZC3H7A,TRIP4,MORC2,PPAN,RBPJ,GTPBP1,STIM1,MAK16,CACYBP,NTMT1,CETN2,LRWD1,OCRL,NOP58,MPP1,RPL7,SPTAN1,WDR6,DNM2,THOC2,PHB1,LYZ,DDX23,KDM2A,EIF3D,TRA2A,TAF7,PRPF19,PSMD3 |
| 6.231e-18 | -39.62 | metabolic process | biological process | GO:0008152 | 8139 | 2661 | 18204 | 5365 |
LDB1,AIPL1,RPS16,STK38L,SCN2B,DDR1,KTI12,CFTR,MTRES1,DIS3L,ACOT8,FBXO3,RPS28,PSMD14,UFM1,TRIR,BOLA2B,SLC29A1,ATG3,SPHK2,PPAN,RPF2,TRIM23,OGG1,ANKH,QRSL1,PLEKHJ1,H2AX,RAG1,FBXW11,SPCS1,STX1A,RDH11,MTMR12,INO80C,EPHA2,MINDY3,PIR,KLK9,MME,HMBS,RPS29,PSMD4,BATF,DPAGT1,PRPF4,MAPK10,BRIX1,CAB39,RNF182,S100A10,ROCK2,APPBP2,ADIPOQ,PLAAT3,GALNT2,CINP,RPS3,EEF2,TMEM106B,SNX14,SENP8,TRIM6,ETF1,FBXO31,TRAF2,RNF187,STX12,PDE9A,DCP2,STK24,GLE1,RNF20,GNPDA1,KDSR,TSPO,BTG2,RAB39B,TAMM41,RPL23,CCNA2,FUNDC2,CSNK1A1,NUDT7,CYP7A1,NSDHL,ACOX1,LIPA,CNOT7,COX5A,GAPDH,PLPPR1,MYRF,GNPDA2,UBE2H,CLN8,RAD21,LSM6,POLR2L,OSBPL8,PLAAT5,MRPL47,PCYOX1L,AK3,ITK,ATP5F1E,AASDHPPT,EZH1,CEP41,SLC25A11,PYCR1,FBXO22,RPS5,EDEM3,TPRA1,GGTA1,PIWIL4,ACSS2,TTLL10,PTPRQ,HELT,NDUFAB1,MTHFD2L,ATXN1L,FGFR1,VASH1,CYB561,EVA1A,SEC11A,CTRB2,DHRS3,TRIM27,FKBP10,MRPS18A,TSEN54,NONO,CDK6,TFPT,FBXL7,UGDH,HUWE1,PTPN11,SELENOP,ENC1,CCL11,POLR1B,HADHA,SPPL3,IDO1,ORC6,TAF7,PFDN1,GNPTG,VPS4A,FHIT,PEDS1,ZMAT5,IL21,APEX2,ACBD7,ZNF451,EEF1AKMT3,VPS72,MTARC2,BAZ1B,CWF19L1,TECR,PRCP,GPX4,CD52,CISD1,MRPL36,NDUFA2,CDK7,ETNK2,P4HA2,ATP1B1,HYCC2,MACROH2A1,ERG28,EDEM1,USP14,PFDN2,HPS6,NABP1,SNRPE,SNRPA1,CTBP1,PRKCB,WDR3,AHSA1,MCHR1,PAGR1,PEX13,TTC4,NPM3,QNG1,ABHD14B,FMO1,EIF3J,PXYLP1,PTPN22,NFKBIB,PDE8A,GAL3ST1,NDUFA1,TRIM37,USP13,UBE2F,ADTRP,FUNDC1,RP9,PIWIL2,FARSA,AP5S1,PDHB,VPS4B,RTCB,PAK6,METAP1,QPCTL,TGFB2,DTWD1,FCN2,SLC6A3,KLHL12,RNF39,POLB,SNRPD3,SRPK2,RBM7,PLSCR3,CPT1B,TCEANC2,SHOC1,ATP5F1B,SNAPC1,PCNA,RING1,NAT2,ABHD12,COPS4,TAF2,WWP1,ZMPSTE24,NUDT5,ZCRB1,IFIH1,ARL6IP5,PPP1R2,EGR2,ATG9A,RPS27L,ARB2A,PLPP6,TRIM26,POLR2I,YBEY,WBP11,SNRPA,USP8,LDAH,CRAT,RC3H2,VCPKMT,SELENOO,MRPS33,SMG5,DCTPP1,FCF1,HTR1A,ATP6V1A,PFDN6,TRIM11,ACHE,SLC20A1,LYPLAL1,CAV3,SMPD2,OXCT1,KCTD17,MSRB1,HSP90AB1,CBFB,CD28,TAX1BP1,PTPRZ1,LDHB,FKBP1B,ERLIN1,CMAS,MBLAC2,PELI3,MARCHF5,HTR2A,INPP5K,OST4,REP15,DAD1,CDK5R1,WDR45,CYP2F1,USP15,HSP90AA1,SOCS4,POLR3GL,NDUFA12,EIF2S2,WWP2,HNRNPA1,NUDT18,MRPL16,THOC2,GLO1,PMPCA,SPON1,KLHL7,DNAJC30,DNAJC19,FMO2,TDRD7,PTGES,PRDX3,G6PC3,SCNM1,APOBEC3G,HSPB2,SLU7,IER3,ANAPC4,CREB1,SELENOF,SNCB,NAE1,SELENOI,CCNF,CHKB,TRAF6,NLGN2,TTC1,GSTM4,NUDT12,THBD,SYCE3,TMEM59,RNF40,ACAT1,TRIB1,RAB19,URAD,TXNL4A,MRPL18,HINT2,HNRNPF,SLC25A44,CYP2C9,RPAP2,FOS,CHI3L1,PRSS12,PRSS37,PHKA1,CLPX,FBXW4,IRF2BPL,MGAT4A,SUPT3H,PLP1,P3H1,LIPT2,NFKB1,THTPA,KCNJ8,GLYATL3,RNASET2,ARG2,TESK1,B3GNT2,UBL4A,WDR83,SETD5,PPAT,UQCR11,ZDHHC4,TYW3,FNTB,GFUS,NDUFA5,ELP3,DNAJC4,SNRNP27,AKR1B1,ATF3,DUSP22,GPAA1,TRMT1L,SMAD3,CMTR1,SLC7A11,ATG16L1,NXT2,SELENOK,IRF2BP1,TRIM62,KMT5B,TEX19,EIF4A3,HNRNPD,TAF9,COL1A2,SNRPN,C1GALT1C1,FAH,UTP15,PIGK,MAN1A2,TMEM208,COX7B2,STYK1,DNAJC5,PQBP1,SLC25A32,SLC30A5,IRF1,KRR1,CA12,FBXO44,NBN,METTL14,HS3ST3A1,GSTK1,TFIP11,NTRK2,ASNSD1,DDAH2,CCT5,TLCD3B,PGK1,RPS24,IFI16,B4GALT4,ETFB,AKR7A2,MECP2,UBL5,TICAM1,AKR1C1,SNX17,COX6B2,EXOSC3,CELF6,LYPLA1,MRPL50,EDC3,BNIP3L,BMPR2,ADGRG1,PPID,SUMO2,PSMB4,ANGPT1,MSRB3,CDK20,SRC,PPIL3,SRGN,MTMR2,NRDE2,GXYLT2,EXT1,PTGES3,XPNPEP1,SF3B6,IDH2,HNRNPK,TRIM21,POLR2F,NOVA1,ATF4,MGAT4B,ATP5MC3,CHPF2,AIG1,CHDH,PSEN2,PLCB2,METTL6,ISCA2,RNF121,RBM27,FAU,MEIOB,RPL8,DTL,GPR37,NUDT4,PGRMC1,ZRANB2,TENT2,BIRC5,MACROD1,USP30,DHX38,TOM1,DLST,OAZ3,PRKRA,MEF2A,MRPL53,ARMT1,PGM1,HBA1,PSMB3,MMACHC,NRBF2,HTRA1,ADRB3,SIAE,ATG4C,WDSUB1,CRKL,GYS1,TRIM24,MARCHF4,RIC3,SKP1,PLAA,CTDSP1,GAMT,CDK12,TSPAN15,CDKL2,CHPF,B4GALT7,BAD,DERL1,ADCY2,EIF3G,PPP1R8,GSK3A,SPTSSA,PSMD7,AKR1A1,KPNA6,GON7,AKAP17A,MRPS35,CDC7,GMNN,UBE2V2,RNASEH2C,LMNA,DPH3,UBXN6,DRD3,ISG20,SDHAF2,GRB10,SELENOS,DDI1,MRPS34,PRMT5,GABARAP,HSD17B10,NPC1L1,PIK3R3,CSTF3,WDR77,RPN1,CRYL1,UQCC3,RFC3,GEMIN8,RNF103,EP300,GPX1,RNF208,TMEM106A,ANXA7,NPR2,SLC1A2,BACH1,CTSK,INMT,RPF1,CRTAP,MFN1,TIA1,RWDD1,ABCC2,ESS2,RBFOX3,HADH,METTL2A,COX6C,MRPL22,INHA,ECRG4,GPX5,SLC35A2,PAFAH1B3,ENPEP,DPH5,APTX,PHYH,SLC25A42,EIF4E3,SIN3A,CHMP2A,ELK1,LYAR,SNAPC3,RMI2,RMND1,H3C1,GANAB,RPLP0,MPHOSPH10,RPL26L1,SNAPIN,POLR3F,VDAC1,HSPD1,MRPS7,PNP,OVGP1,MAT2B,MORC2,VPS33A,RNF122,OSGEPL1,SLC1A3,UPRT,LUC7L3,GNMT,MRPL11,ADGB,IMPA2,SULT1B1,WSB1,THUMPD1,PRELP,RNF14,UBE3A,SNRPB2,DPP10,DUOXA2,RNASE6,POLR3B,UBE2E2,ASMT,STOML2,CAMLG,UBB,TMT1B,BGLAP,COPS7A,USP2,BOLA3,KCTD9,NLRP3,PDHA1,H2AB1,RP2,PPM1D,RNF133,GGCX,CHST7,CSNK2B,ABCF1,NHEJ1,FUT8,CASC3,CDKN1A,LCN1,LRAT,MPST,LSM3,TOP1,MED4,SUPT5H,FDFT1,ZNF365,SLC22A12,TNFAIP1,CD2BP2,GGT7,TAFAZZIN,RPL6,CASP4,ILK,RNF152,RPL28,CERK,CDK5,KLHL9,PLAC8,RSL24D1,DNAJC10,STUB1,CYP3A5,CYP4F12,GTF2A2,DUSP10,CCT8,PITPNA,PCLAF,HECW1,RNF5,KDM2A,MUL1,PPT1,GINS4,DUSP18,CYP17A1,EXD2,RPA2,PHB1,ERLEC1,MID1IP1,RDH12,NEK9,TEX12,CAMKV,SLC25A12,FYTTD1,ASB7,NAA35,B4GALT3,DDX46,CDKN1B,TRIM52,TRA2A,PPP2R3A,LYG2,CHMP4C,RBM3,RETREG1,TRMT61A,RBM15B,UFL1,SDHAF4,TRIM15,CYP27B1,WDR6,KPNA2,METAP2,LGALS3,DET1,CDC123,DROSHA,FAR2,HEXB,CYP2C18,ZNF326,FAF1,PIWIL1,PPIB,HSPA8,SCD5,PTPN1,INTS10,BAG2,ZNF473,ZNHIT3,RPL9,RARS1,IFI6,CYB5B,MRPS11,USP39,ALKBH3,SORD,CRBN,RBMX2,FBXO30,CLCA1,ST3GAL4,TP53,SPCS3,MAP1S,PSMB5,UQCRH,PYGM,SUMO3,MDM2,TRMT13,FADS2,UBIAD1,MPG,AGA,HENMT1,POR,RPL35,DDX5,SLC25A39,NCBP2,PCMTD1,SOX9,NDFIP1,CBL,SART3,BAG3,PPIG,ERO1A,GHRL,CPEB1,CSNK2A1,HNRNPA0,VTA1,DHRS7B,PTPN5,CPSF4,AZIN1,DCAF5,DNAJC25,MVD,RBM23,GLRX,CYP1A1,LSM8,QTRT2,MTRF1,CWC15,IMP4,NR1I2,CTSB,PPTC7,DHX15,ANAPC11,DNPH1,PRPF19,PELO,ING5,CDC5L,OTULINL,CTTNBP2NL,FKBP1A,EIF4EBP2,XXYLT1,VIPAS39,SNRK,NUCKS1,IRF8,DRG1,HSPA14,RPP25L,OLA1,GLRX2,VAMP8,RAB1B,CHRAC1,FKBP2,RFC2,DBR1,LDHA,ZNHIT6,SRSF7,DDX4,ADRB2,PRDM4,CFAP20,HAND2,MCM8,PRSS1,C9orf72,RNF8,SETD9,STAT6,MAT2A,FAM8A1,THOC3,SF3A1,ABHD13,KLHL15,ST6GALNAC3,FPGT,MAP2K3,DUSP3,ZFAND2A,LRWD1,CHST9,GFM1,PLD3,TMUB2,DPEP1,OTUD7B,RPRD1B,LORICRIN,LSM2,LTO1,GZMK,SMNDC1,SUGP1,AANAT,SLC2A3,PAOX,IL4,NDUFC2,GTF2H4,PSMB10,PAAF1,NTMT1,CDC37L1,THAP1,MDC1,DGCR8,RPL37A,FAM98A,PDP2,ATP5PO,FXN,CSNK1G3,RPL17,F9,GPBP1L1,TRMO,CHID1,MOXD1,CYP3A43,NEU1,GSTA2,RUVBL2,USP5,SLC25A17,YAE1,COG1,LANCL2,CMA1,SWAP70,RNF7,EIF5A2,SOD3,PCSK2,REN,SHPRH,MIF,NXT1,NDUFS8,STK3,FBXO8,RNF34,SLC48A1,SETD7,GDE1,MAP3K12,UST,ACADSB,PDE7A,ABCB9,RPS14,TLR3,DDX42,TRIM68,CDC16,HACD2,DYRK2,RGS19,SREK1IP1,SECISBP2L,CRYAB,AGO1,SOCS2,DUSP19,FZR1,ALDH1L1,MTMR6,PPP2R5E,USE1,TBCEL,PRPF31,RARRES2,G6PD,MRPS25,MYLIP,DMPK,C1D,APOBEC3A,CDK4,ACOT13,TBK1,CYP21A2,XRCC5,RPL7L1,PIAS1,VPS54,TRMT10B,DPP4,PDE2A,RMND5B,KIN,EIF5B,RBM42,DNAJC1,GCFC2,DUSP6,PHF23,PSMC5,CCL2,GLRX5,NPPC,RPL10A,SLC16A10,PCYT1B,HNRNPL,NLRP1,MAK16,SYK,NPY1R,TRIM5,SELENOT,ZC3H11A,APOBEC3C,PPIC,EAF2,S100A8,TESC,ZDHHC17,PRDX6,FBXW7,RBM17,CERS2,UBAP1,APEH,VSIR,LGALS8,DCUN1D5,RAB33B,CNOT6L,PSMC4,FA2H,MED23,KBTBD6,RAB33A,MED9,ABHD16B,TRIM32,TRMT112,UBE2L3,GPAM,PRKACB,RNF148,YWHAZ,CTNNBL1,TERB2,BSCL2,KLF1,AGK,PIK3R2,VKORC1L1,ST3GAL5,CDCA3,CAMK1,CDC40,PTDSS1,STT3A,NDUFB8,AREL1,CAPN2,ELOVL4,HS2ST1,DEK,RRM1,PPM1B,ALPL,MTPN,NUDT16,EIF3E,FGF23,CYP4V2,RPS11,UNC45A,PDE1B,NSMCE3,GTF3C4,MGST3,METTL21A,SAMHD1,PPM1K,CLK1,ALKBH2,VRK1,CTSA,ADPRH,MMADHC,ASB11,CHTOP,RB1CC1,NDUFAF6,LRP10,PRDX1,RNF41,UGT2A3,HSD17B8,CD40LG,PARP11,TFEB,FAHD1,PDE4B,RBM41,ACO2,RPL35A,BACE1,UTP25,APEX1,MAP3K21,ZC4H2,DPH6,CHST13,ATP5PB,TAF10,PIK3CA,F7,ELOVL3,FBXL3,NMRK1,RPS10,ZFAND2B,CYP39A1,CDSN,GPIHBP1,SUPT4H1,GFM2,ROCK1,THOC1,RHBDL3,SPSB1,PID1,SLCO1B3,DOLK,MND1,TERC,PFDN4,EHHADH,RPL13A,RPL27,PNPO,XBP1,SNAPC5,SOD1,MRPL52,AR,CYTL1,PAK2,TRIM63,IL2,GDPGP1,HIRA,PAIP2,PCSK9,B4GALT1,USP46,ACP5,RPL4,TAF11,PPP3R2,CKB,PIP5K1A,SMU1,DIO2,PARL,DCK,RGMA,PRKCE,PSMA3,GLCE,SRFBP1,B3GALT2,ATP5MC1,SIAH2,BMP1,CA10,CEBPE,GPC1,LBR,FKRP,RPL26,PDRG1,CCT7,FUBP3,DUSP26,ACO1,HACD4,RPS4X,PIP4P2,PSMA4,PSMD6,SIRT7,ASPA,COX6A2,FBXO9,DIO3,PPP1R11,FEM1C,CYB5R3,CLK4,PRPS1,B4GAT1,BAK1,VDR,DUSP14,MTAP,TKTL1,ZBTB16,HDAC3,UBA3,ATG7,MMP20,RAMAC,JKAMP,PSMB2,TNIK,UBE2S,B3GALNT1,AQP11,MDH1,DNAJB6,HM13,PREP,RIMKLB,WNT10B,CRYZ,RIGI,PAX6,UQCRC2,URM1,SMYD3,GFPT1,PRKAG1,TUFM,CASP12,SLC35C1,TP53INP2,NUS1,CHMP2B,OTUD6B,PNPLA8,BABAM1,OPTN,RPL7A,DRAM1,CA2,AKT3,RCL1,FOXP3,AGPAT5,PPP1R12A,PPP2CB,ACTL6A,DUS4L,KLHL25,GPD2,TENT4A,PAFAH1B2,CLIP3,RNF181,SNAP29,GNPNAT1,RPL12,MMP14,MCM6,ABHD4,UBE2K,THOC6,POP5,IMMP2L,POLD4,MAGEC2,UQCRC1,PADI2,CHMP1A,DDX39B,CETN2,PTP4A3,CDIPT,UTP6,NDST1,AHCYL1,TP53INP1,EIF4E,ACVR1,TBC1D5,RAD23B,AZIN2,EIF4E2,CA14,MTHFS,RNF144B,WDR83OS,GANC,MCMBP,TBC1D17,PRKCA,LMAN1,HSD17B1,CAPN1,PLSCR1,F2,EDEM2,AMT,PIP4K2C,POMT2,RIMOC1,PPIH,USP16,RABGGTB,APOBEC3B,SH3GLB1,CYC1,HSP90B1,ELOVL6,RFC4,DCUN1D1,PGGT1B,UBE2E3,TSEN34,FRA10AC1,EEF1B2,INPPL1,GSTT2B,STRADB,NUDT3,ECHDC1,CGAS,TFB1M,DAP,GPX3,GUCY1B1,TRA2B,NFE2L1,RAB6A,H2BC1,EMC6,VPS28,KLK6,FEM1A,KCTD11,DFFA,ABHD17A,ZDHHC8,PITPNB,MBL2,HMGB1,CARS1,CD226,HRAS,PYCARD,GTPBP1,HNRNPH3,BCCIP,SRSF8,STN1,SRSF2,GID4,RAF1,POLDIP3,MMP21,NAA15,ZC3H15,RBBP7,MAP3K11,DDRGK1,PPP1R1B,VAMP7,PRKX,MSX1,RAB2A,DBH,TRAF1,RFC5,FAXDC2,GOLGA7B,HDHD5,SLA2,PRKCQ,SESN2,ADH1A,COP1,SDHC,SPCS2,GSTO2,GABARAPL2,UBR7,HECTD1,UFD1,JOSD1,B4GALT6,PPARG,POLE4,DESI1,ST8SIA4,MKKS,FANCG,EGR1,PNPLA4,CHCHD4,IKBKB,PTGDS,EPO,NR4A2,CUL2,MNAT1,ADCK1,EZH2,UPF3B,EIF4H,NCSTN,YTHDF2,RPS20,CHMP1B,RRP7A,ADORA1,PRDX2,RAC2,TBCE,COMT,PSENEN,CMTR2,SRSF1,PLPP4,EYA3,DDIT3,DNAJC2,POLE3,ENO2,DCLRE1C,SMG9,NOP9,FKBP8,CTSC,LCMT1,SVBP,ERCC3,ABCC5,CHST10,HSD17B11,ATG101,PGAP4,UBE2D3,COX10,CYGB,AIP,ATP5PF,MTF1,PLA2G12A,MRPL9,FEN1,TRIM22,PTTG1,HSPE1,ADAMTS20,ATP1A2,PYM1,TST,CSTA,ILVBL,KGD4,XPO5,LDHAL6B,COIL,RETREG3,PGPEP1,CCT2,SMAD1,RNF126,HNRNPC,METTL25B,OAS1,SETD3,IDH1,EEF2KMT,COPS5,SUMO1,COX8A,MAP1LC3A,FOSL2,ORC5,DYRK1A,GSTM2,PGAM1,EIF2D,PRSS23,GCLC,SELENOM,SLC5A6,ZDHHC24,RPL22,PROX1,CREBBP,MARCHF3,KLK3,DDIT4,MPDU1,RBP2,MRPL40,ADAMTS10,GTF2H5,PPP1R3C,SAT2,DCAF11,DPY30,STBD1,KRAS,DRG2,IL2RG,RPP21,ACADS,ADAMTS1,FBXL4,CPT2,NUDT2,ETFRF1,TWNK,BRCA1,ALKBH5,BUD31,TRAM2,SMAD2,LIX1,CYP2D6,IRF9,MPHOSPH6,RBM22,MTM1,PSEN1,TNKS2,MRPS21,DTYMK,RNF113A,SLC19A2,SNRNP70,IDE,APOBEC3F,MRPS23,SNRPG,UBE2I,MTG1,NDST3,RBFOX2,TNKS,TAB1,PRDX4,MCOLN1,RBBP8,SOCS3,CAV1,CELA3B,PPP1CB,COQ8B,MEPCE,RPP14,POLR3H,ACOT6,IDH3B,ST3GAL1,NDUFA4,RAB1A,NME4,ODC1,PIM2,CDKN2D,NAA60,ATP6AP2,SSBP1,POLR2D,CDK1,SNIP1,RPS6KA4,DDT,SRM,OAT,APOBEC3D,ISYNA1,CYP26A1,UBE2A,PWP2,GLYAT,NAA50,CTDSP2,MED21,NFIL3,PREPL,MRPS26,FITM2,FAAP100,COX7B,GSTM3,TPH2,CASK,MRPS28,CYP4F8,SLC35A1,HSPB1,SLC25A1,TDP1,MARS1,FAF2,DAPK1,ZSWIM7,CDC20,ACTMAP,RPL23A,TYW5,FBXO11,ZER1,NDP,FKTN,DNLZ,CSGALNACT2,NAA11,UBLCP1,VPS16,GADD45A,DNAJC7,FAM20B,TPST1,ZDHHC16,MRPL24,TSR3,NEK2,FMO3,CD2AP,CD38,UMPS,MMAA,SFTPD,TMEM74,UTP23,GRM2,NUDT9,CBR4,PML,SNRPD2,DISC1,SLC11A2,RPL32,UGP2,BMPR1B,TFCP2,GSTT1,MRPL20,ALOX5AP,PABPC1,MRPL33,UBXN2B,SPATA2,HS3ST1,TERT,GTF2E2,NDUFB5,EIF2S1,RPL24,FUT9,OTULIN,ANAPC13,RPL3,SDS,MED30,RPL19,CISH,CLU,ADIPOR1,PSMA1,STK38,GRPEL1,PKNOX1,RPS7,RNASEH1,HSD17B6,CRTC2,EIF1AX,SARM1,PCBD1,NT5C2,ATG4A,TEX264,ELOC,PNRC1,POLD2,PHKB,GSTO1,DTWD2,TRIM3,ALYREF,GTF2IRD1,RPP25,PGS1,EIF2B5,EIF1AD,MGAT1,EIF3K,SNAPC2,CCDC3,NTRK3,HACD1,NOB1,IVNS1ABP,SMARCB1,BMPR1A,SACM1L,GOLGA7,SFXN1,FBXO7,HNMT,GCNT3,NFE2L2,DNAJB4,AMY2B,COX17,PTS,AKR1C2,PRMT6,UBASH3B,SPSB3,SMUG1,SRSF4,RTL4,PDIA6,EI24,TRAPPC4,DRAP1,TMEM199,SLC38A1,EIF1B,SMARCA5,PIWIL3,SERPINH1,SDR42E1,DAG1,SLC25A21,NME1,CMBL,CSTF2T,PDSS2,KCNJ11,MMP28,POLR2G,SQSTM1,RAB40AL,LEP,SNRPB,MCM3,MRPL51,CBLL1,TCOF1,PHB2,MED17,GALNT1,PLCL1,SERINC3,RNF146,SENP5,METTL22,CPSF1,COMTD1,ELOF1,STK16,TRIM45,TESK2,SEC61B,MRPS18B,EIF2AK2,POLL,HPF1,RIOK2,DESI2,CYP2C8,UBE2N,RRN3,ATP5IF1,PSMC3,STK26,TM9SF1,NUP153,UBE2M,INTS6L,USP3,TSR2,CAND1,VLDLR,GALNT17,PTEN,JAK2,APOC4,LYZL6,DTD2,DDX39A,MORF4L1,MED31,FBXL19,SMCHD1,ABCE1,ACACA,TUBA1A,UGCG,GSTM5,ASF1A,CRY1,POLR1D,HBM,DCAF16,PYCR2,NOP53,PHETA2,UBE2G2,BRS3,UBE2V1,INO80E,SMAD4,GMPPA,ASB3,RPS27A,MAPK4,PDIA2,LSM4,DNASE1L1,RNF128,ARMC8,POP7,COQ10B,GK5,CAMK2G,KARS1,EIF3D,PSMD12,NAA16,PRKD3,MAGOH,TTL,RPSA,SNX5,DR1,CERS6,NTAQ1,CYFIP2,COPS7B,KLK5,GPT,TSNAX,IAH1,SHLD1,HYAL2,CTNNB1,CYP2R1,SLC1A1,OGDHL,JAK1,HACD3,UBE2B,GUK1,RHOBTB3,CREBL2,PRPSAP1,MAEA,SYNCRIP,NGDN,SMURF1,PCK2,SLCO1A2,DNM2,NOS1AP,PSKH1,COX7A1,ECD,RPS2,EEF1G,ETFA,MIR21,ELP6,WDR82,ANAPC2,PHKG1,KLHL24,UQCRQ,DHRS4,CPNE1,ELOVL7,DCAKD,MLH3,NEURL2,ENTPD3,ADCY3,MED29,KHDC4,IFI27,RPS23,HSPA13,PC,IREB2,NDUFS3,RPLP1,DXO,LIG3,HYPK,SRSF10,CD36,BAP1,PMAIP1,TRPC1,DMAP1,LDLR,AURKAIP1,ENO1,HAS3,TOP3B,TRIM34,TRAF7,UCK2,RPL39,PAK5,PELI1,PPARA,ST13,EEF1A1,NEUROD2,ADRB1,LANCL1,GAL3ST4,PPP4C,BRAP,RNASEL,RPS17,FGR,IDH3A,NIM1K,THRAP3,CRMP1,COX6B1,VIRMA,GTF2F1,CSK,ABHD6,ERP29,STAMBP,NDUFB6,NANP,PI3,KBTBD13,RBM38,CNTN1,SNRPD1,CEBPG,GTF3C3,CNDP2,GALNT12,CHST2,MAPKAPK3,OTUD6A,PYGB,CTSD,MFAP1,ALDH1A3,SDHB,RETREG2,DCTD,SDR16C5,TMEM39A,CDK9,RBM5,FOLR1,NFYA,CITED1,IK,PTPMT1,RB1,ELOVL1,RNF141,SLC25A5,RSRC1,TYMS,CYP11B1,PRPF18,NSFL1C,TOPBP1,BCKDK,RAB11B,BCL6,SH3BGRL,HFE,PFDN5,DDAH1,SSU72,ORMDL3,TOP2B,CSKMT,PSMD3,PLG,ABHD5,ITGB8,HINFP,MRPL34,OAZ2,FBP1,FITM1,ATP5MK,EPHB6,MED11,SF3B1,TMUB1,COX4I2,TNF,SHMT1,GALC,GRPEL2,CYP11B2,HMGA1,RUVBL1,PDE12,PDIA3,PSMA2,CDK8,DIO1,SLC25A4,TNFAIP8L3,IRAK4,MRPL10,CHMP5,PCMTD2,SUV39H1,GSTA1,PPP2R1A,CDO1,SNRNP40,NQO1,BPNT2,ALG2,PPWD1,KLHL22,APOBEC3H,SGTA,SC5D,GMPPB,F10,AOX1,PAPSS2,RPL15,MLF1,SLC16A1,APOC2,GAPT,SIAH1,PTPN4,TRIM44,RBCK1,ZNF668,S100B,HMCES,HINT1,CBR3,RNF139,TCEA2,GTF2I,ATAT1,EIF2B2,PRIM2,B2M,PSMB9,RPS26,GPHN,CYB5R1,GABARAPL1,LARGE1,GHR,UGT1A1,EMG1,MGMT,TMEM38B,TRIP4,CRABP2,SAP18,RAD1,ITGAV,CHORDC1,GEMIN7,CNOT8,MPP1,TLR4,RPS15,IMP3,TMEM165,HMOX2,POLR1H,TSSK1B,INPP4A,PIP4P1,TOR1B,IP6K1,KLF4,B3GALT1,SPTSSB,ST6GAL1,MAEL,VCPIP1,STK4,GNAI3,CIAO1,ACCS,CDC26,PIGC,DDX23,MCM4,CSGALNACT1,ANAPC16,OAZ1,ZC3H7A,ASCC1,FTSJ1,CNP,PTAR1,LEPR,SOD2,NEK7,NDUFV2,MAP3K3,PPP1R1A,FBXL14,TNFAIP6,EPOP,MRPS17,ALG11,PDF,OLR1,CYBC1,SUB1,RGN,RPL7,TMT1A,EXOSC4,IL1R2,NSA2,HCST,UBXN10,SF3B5,CNOT6,SLC25A14,CHST11,DLG1,DNAJB9,BANF1,DICER1,FIS1,PSMB1,HBB,COX4I1,POLA2,TNNI3K,BECN1,TOPORS,ZCCHC7,GXYLT1,KDM1A,GAD2,OS9,TLR7,ZBED1,BUD23,RIMKLA,TSN,NHP2,CTU1,MAP2K1,PPP1CC,SLC19A3,PRMT2,HGS,CCS,MAP3K14,STPG4,FEM1B,PLA2G15,SPP1,FAM20C,HSD11B1,AMACR,SEPHS1,RPA3,SDF2L1,DHX9,GDPD3,COL3A1,CA8,PGM2L1,MSL2,RMI1,ZNF345,MARCHF9,RNF167,SULT1A3,ISG15,GINS3,GALNT4,UAP1,CCR6,OSBP,ATP5MG,GTF2B,NEDD8,RLIM,DHRS7,RPIA,PDE1A,UCHL3,TPSG1,PGAP2,TRIM8,LIAS,HYCC1,RPL29,EIF2B3,RNF11,ZMAT2,TRMT5,LTB,TRIM54,TAF5L,MYD88,SPOP,SOCS5,HSPA5,KLHL3,HTRA2,NUDT1,SLC25A51,CYP4F22,IGFBP3,MRPL57,RPL10L,SLC6A8,LSM10,EPHX1,SNRNP48,FURIN,RPL18,AK2,SSH3,GALE,ALG5,FASTKD5,THG1L,EEF1E1,GSTA4,STAMBPL1,FBXO25,VTI1B,ANAPC15,MYORG,MRPS16,BLVRA,RPS9,PLCXD3,HERC3,MAP1LC3B,SLC6A7,PMM2,ATP5F1A,YWHAH,SRSF12,OSGEP,NDUFB7,BARX2,TSSC4,ETFBKMT,GTF2F2,IL6ST,PELP1,MMUT,EPHA4,GBE1,TUSC3,SPR,PTP4A2,ZDHHC15,METTL24,PGAP3,AUH,PPIA,ABHD10,GGH,PLA2G4B,ARMC7,RTRAF,IGF1R,RCHY1,SAT1,IFT172,CSNK1E,FBXO32,DPEP3,ST8SIA5,CYP1B1,FKBP4,TLR2,ENTPD4,RPS13,HBE1,GTDC1,MRPL13,DUSP9,CCNH,PPM1M,MRPS9,SGMS2,MRPL12,STAT5A,PPIF,BPGM,RNF26,TRMT6,MECR,AKAP8L,PICK1,RNF10,CSNK1A1L,YIPF5,PTHLH,WBP2,HPGDS,UCK1,EHD3,MAPKAPK5,POLR2B,NUP62,H2AC25,MRTO4,MGAT5B,DHRS11,MAP2K6,HSD17B3,RDH10,CACNB4,CHRM3,PIGA,DRD1,PIH1D1,EXTL2,DCUN1D3,ATP5F1D,NOC4L,TMBIM6,ARFGEF1,SCG5,MSMO1,MED10,ACVR1B,DERL2,PPME1,GK2,BFAR,CH25H,PSMC1,LAP3,MED22,CCAR2,STK11,TMCC2,ALKBH4,NOL7,INTS12,DPM2,SGF29,MRPL17,HDAC6,FOXA3,POLDIP2,NME2,WEE2,PRSS8,PARP2,XPO1,UCKL1,KCTD10,TCEA1,LHB,SLC2A1,MCAT,ERH,YES1,BIRC2,DUSP1,SLC23A2,LACRT,STAR,EGLN3,MRM2,NPC2,PRKAB1,ASB1,RLIG1,VMP1,GLUL,MRPS18C,PGA4,CPSF2,NDUFS6,PSMD1,SETD4,CUL3,SBK2,SSRP1,CDK17,CCDC47,ZNRF1,RAN,PIK3R1,TRIM10,TRUB1,MRPL49,CRYM,PIGY,NIBAN2,STX17,AK5,SLC52A3,TCP1,ASB8,GTPBP2,FABP5,BCL9,RCE1,MRPL41,PPM1G,IL15,NDUFB4,GTF2E1,ABHD2,HSPB6,RPS12,CCAR1,PRRT1,CMPK1,RNF115,LYZ,HMGCS1,RPL31,G2E3,WRAP53,TOR2A,TRIM35,NT5C3A,NDUFB10,PBLD,CHST1,GTF2H2,INSIG2,VAC14,HNRNPA2B1,PIK3CG,GIN1,ANKIB1,TRMT11,ADH1B,COX11,RETSAT,ABCG2,NUP107,RBMS2,FIG4,CDC23,APMAP,GMPS,ADK,NDUFS2,WDR12,SPOPL,PAFAH1B1,WDR55,DBT,GNPAT,MAGOHB,ADRM1,DECR2,CAMP,SERINC1,OARD1,LYPLA2,CACUL1,KIT,SLCO2B1,COQ8A,CPE,EIF4A2,MET,TOLLIP,CYB5R4,TSPAN5,RPE,UBE2D1,HNRNPAB,MSH6,TP53I3,TGFBR2,MATCAP1,FTSJ3,PLA2G5,SLC25A26,NR1H2,PPP5C,TSG101,E4F1,RPRD1A,FN3KRP,EGLN2,SCPEP1,ACER3,PAXX,DOHH,CDK5RAP3,SLC25A10,SPRR1B,SYVN1,IL1B,ESD,AKT1,DYRK1B,ACP2,PPP3CA,HERC4,CLP1,KBTBD2,ELAVL4,ADAM21,SLAMF9,EIF4B,PFKFB2,DNAJC24,VPS39,EXOSC8,TLR6,UBA52,PCCB,MTERF2,METTL15,RTF2,NSG1,CALR,SKIC8,PSMA5,ABCB1,CHCHD1,TTR,GRSF1,ENY2,UBE2W,WTAP,CNOT2,MRPL23,UCP2,SGMS1,IGF1,APH1A,ROMO1,DKC1,ATP5PD,MT3,INPP5E,TXN,GID8,GSTP1,TNFAIP3,RBBP4,NUDCD3,METTL18,RPL10,MGST2,PSMB11,SMG8,PPP2R5A,ADM2,PLCB1,ORMDL1,DTD1,DNAJC3,ST3GAL2,B3GALT4,LPCAT3,RBM34,DNAJB2,SRD5A3,CDC73,CDKN3,OCRL,DHX16,RPL27A,DSTYK,EDNRA,NMI,MGME1,PSMB6,PAPOLA,REXO2,DHRS4L1,MAD2L2,GMDS,ADSS2,NCAPG2,GTF2A1,MED27,PIGW,EXOSC1,TAPBP,NUDT19,ASRGL1,DUSP21,VPS18,UCN,ACP6,DHPS,ERRFI1,FUT1,UHMK1,SLC37A4,DLAT,COPS2,PSMA6,HS3ST5,AKT2,GGPS1,RPLP2,HECTD3,SMN1,DAPK3,GPR137,SLX1A,SF3B4,OXSR1,ZDHHC14,TBC1D25,ERLIN2,DDX1,POLR2C,SUCLG2,CHAC2,CYP27A1,NKX3-2,ACSL4,FBP2,DCAF4,ACVR1C,SLC2A8,DNTT,RAB23,PSMB7,SEPHS2,ADAT1,ADIPOR2,DEGS1,NOP58,MMP9,ACAA2,LSM5,PAIP1,IL6,LAMP2,AGPAT1,TOM1L1,ENPP4,GP9,USP38,HEXA,BAX,TRAF3IP2 |
| 8.590e-18 | -39.30 | RPS4X (ribosomal protein S4 X-linked) | protein interactions | 6191 | 445 | 209 | 19454 | 5460 |
RPL17,MEPCE,NEDD8,RPL3,ABCE1,RNF8,ARPC3,DNAJC2,TFCP2,RPSA,TP53,UBL4A,KBTBD4,CDC5L,DKC1,TMPO,RBM42,RPS27L,CAND1,RPS16,FZR1,RPL32,USP15,RPL10A,RPS2,SNRNP70,RPL24,TUBG1,API5,CD81,COPS5,CSNK2A1,ENY2,HSPA5,RPS15,RNF113A,EXOSC4,NLE1,BAP1,RPL27,HEXIM1,UBE2M,RPA2,CFTR,SMURF1,RPL10L,FGFBP1,RPS3,PSPC1,UBE2H,EXOSC1,IGF2BP1,RC3H2,SPOP,EIF3G,RPS17,RPL7A,SLC25A1,KRAS,RTCB,RUVBL2,PABPC1,RPL31,RPS23,RPL18,EEF2,RPS7,SOX2,HSP90AB1,SUMO2,RPS10,EED,DRG1,PEX3,AGR2,CTNNB1,DDRGK1,XPO1,WWP2,RPL6,IFI16,STAU1,UFL1,HSPA8,HDAC5,RPS28,PYM1,DDX39B,PIH1D1,EIF4B,RPL27A,MTF1,ESR2,RPL10,TRIM29,MATR3,SMU1,CMTR1,RPS26,ICAM1,COP1,ATG3,RPL39,BTF3,MYC,RPS13,VRK1,TRIM63,HUWE1,IGF1R,RPL23A,FAF1,SRP72,ILF2,RPL15,EEF1A1,FBP1,CDK9,RPL35A,RCHY1,KRR1,ACTA2,RPL12,SRP14,HDAC6,BRIX1,PIAS1,RPL4,HMGB1,FBXW7,NF2,SIRT7,RPA3,HNRNPH3,RPLP0,H2AC7,GRM2,METTL14,CCL3,UBA52,TPT1,RPS14,VIRMA,RPL22,SH3BGRL,RPL13A,NDN,RPS20,TRIM24,PTEN,RPS12,METAP2,CCNF,PPP1CC,USP14,AR,RPL26,SSRP1,RAD21,RPS27A,RBBP7,TNF,G3BP1,RPS24,HECTD3,SLC25A5,TRIP4,RPS11,NGB,CHMP4C,EZH2,RPL29,B3GNT2,RPL7,NOP58,RPLP1,RPLP2,PHB1,RPL8,FOLR1,RPL9,RPL23,AHSA1,RB1CC1,EIF3D,G3BP2,COIL,H2AC1,EMC9,PPARG,KCTD12,CDKN1A,NOTCH2,WDR77,RPL19,GGPS1,RPL35,SEC61B,RPS9,RPL37A,FAU,RIT1,HSP90AA1,RPS5,RPS29,PDE4B,CUL3,CUL2,ACO2 |
| 8.725e-18 | -39.28 | M (membrane glycoprotein) | protein interactions | 43740571 | 1057 | 422 | 19454 | 5460 |
TMEM209,USP8,CERS2,MTDH,MAVS,ARPC2,SQSTM1,FADS2,HSP90B1,JUP,CDK1,LMNA,CNP,SIPA1L1,RBFOX2,TECR,YES1,SNX3,ACAT1,GANAB,SMAP2,EIF4A3,VAMP3,STUB1,REEP6,EPHA2,XPOT,NAPA,KPNA6,PYCR2,FLRT3,PRDX4,CTNND1,ARF4,HSPE1,WASL,SNAP23,EMC2,PC,HSD17B10,UNC50,DLG1,STX8,EHD4,CASK,ILF2,TMEM94,DDX39A,NECAP2,TBK1,CCDC47,CAV1,ATP5PD,ALCAM,SEC23A,CDCA3,C2CD2,EHBP1,AIFM1,HACD3,SRPRA,DNAJC7,ESYT1,RAB23,ZDHHC17,PSMC1,NUBP2,HADHA,ATP5PO,RAB6A,EHD1,FAM234A,CHP1,DYNLL1,MB21D2,SARM1,SLC30A7,AP2M1,PELO,CYB5R3,LMNB1,MCM3,GGH,TOMM40,RHEB,VEZT,ETFA,SLC39A7,NDUFA4,AKT2,PLD3,AP2S1,STIM1,TMT1B,TPD52,MARCKSL1,RAB11B,OS9,NDUFS8,ERLIN1,SPTAN1,SNX1,SNX2,OCRL,GJA1,NEO1,XPO5,PHB1,WDR6,SLC25A21,WDR11,STOML2,UBXN6,CLPX,ABCC2,ZC3H15,RAB9A,BANF1,GIT2,VPS54,VIPAS39,TRAM1,MRPL10,SPTBN1,ROCK1,CEP41,STX10,MRPS28,EIF2S2,PSMC5,LIG3,SNX5,CALU,ATP1A1,HFE,SLC6A6,EXOC5,C9orf72,FKBP8,TMEM33,KPNA2,SRPRB,TRAFD1,RAB13,SLC16A1,ABCE1,RAB27A,SLC25A11,ATP2B4,SPRY1,TAB2,TMEM165,NECAP1,NFE2L2,ACADSB,TFRC,TFCP2,UBIAD1,SNAP29,PREB,CD99L2,ILVBL,TMPO,DNAJC1,ARL6IP5,RPS16,COMT,CAMLG,STT3A,NOS1AP,SELENOS,RBFOX3,DNAJB2,KARS1,SLC18B1,EMC1,RNF5,SNRPA,KLC2,FAM8A1,SIGMAR1,TMEM115,PAK2,CTBP1,PALS2,YIPF5,TIMM21,ATP5F1B,CAVIN2,SLC38A1,GCC1,LAMTOR1,SPCS3,PCCB,EPS8,TMEM38B,RPL28,VDAC1,DNAJB4,EFNB1,TMEM87A,NUDT19,PCDH19,CCDC134,ARFGEF1,STBD1,VAMP7,EIF2S1,PTK7,TBC1D5,PPFIBP1,CDC42EP4,YKT6,SLC7A1,PDHB,SPCS2,RTN4,DVL2,STAMBP,STOM,PICALM,GOLGA5,SLC12A2,GABARAPL2,KDELR2,SLC35E1,UBA52,PIP5K1A,ARHGAP1,SEC22B,COQ8B,PDE8A,RABL3,FERMT2,ODR4,ENO1,GGCX,AP2A1,ARFGAP3,HMOX2,DHPS,ADD2,RIGI,FASTKD5,ERLEC1,GARRE1,RAB1A,CIBAR1,EXTL2,NCBP2,TOMM70,RPL35A,BOK,STARD3NL,PTPN1,OSBPL8,DAG1,ATP1B1,HM13,STX7,CMTM6,SRM,YTHDF1,CYFIP2,CDC42EP2,PRKD3,ATP2C1,SLC25A3,ARCN1,H2AC1,VAPB,USP39,NOTCH2,PGRMC1,PLSCR4,TOR1AIP2,JAK2,NDUFAF4,BORCS7,GPR37,REEP4,THBD,GPR89A,FAM91A1,FAM177A1,SLC23A2,HSP90AA1,SCFD1,RPS5,CNIH4,PPP1R16A,SLC16A4,MRPL16,MAP3K21,PMPCA,PYCR1,PKP4,NIBAN2,FANCG,AHCYL1,RPS27A,ACADS,BAG2,MRPS11,PCNA,HSPD1,SCYL2,SLC25A5,STX12,RAB6B,BZW2,RPN1,ERLIN2,IFNGR1,FAF2,PPP2R1A,ARFGAP1,MACO1,CSNK1E,NUP35,PPIA,AFAP1L2,ATP6V1A,SNX17,PLEKHO2,SLC20A1,HAX1,CDK5RAP3,IFIH1,RAB32,ATG9A,PIK3R1,PDIA3,GRPEL1,FTSJ1,SNX33,ARFIP1,ITM2B,PSEN2,MAIP1,TEX264,LEMD3,SSR1,CDC42,CTSB,DAPK1,INTS12,SEC61A1,NECTIN2,ALG2,CDIPT,SORD,ENDOD1,ATP1B3,CNNM4,GORASP2,ARHGAP21,SLC25A1,NDUFAF2,CSE1L,AKAP12,ATP1A2,YIF1A,SYNGR3,GNAI3,SURF4,LMAN1,STX6,SLC38A2,SNAP25,RPS27L,VTI1B,CAND1,UBE2G2,SSBP1,AKAP8L,KPNA1,PYROXD2,SLITRK5,GAPDH,DHRS7,SLC37A4,ABCC5,PHB2,NDUFS2,GOSR1,TRA2B,CNKSR3,CAV2,CSNK1A1,LMBRD2,EDEM3,MRPL12,BET1,USP6NL,DLST,VDAC2,CDC42EP3,SERPINH1,CKB,SLC30A5,RALGAPA2,STX16,SNRPB,LDHB,HNRNPC,RAB18,VAMP8,MYO1B,GNA11,HGS,SPG21,TMBIM1,HSP90AB1,OSBP,RAB1B,STX5,DDX1,DDRGK1,XPO1,PTDSS1,SEC61A2 |
| 9.006e-18 | -39.25 | nucleoplasm | cellular component | GO:0005654 | 4159 | 1432 | 19108 | 5553 |
SGF29,APOBEC3B,RPA2,RNF14,MED23,PSPC1,ZBTB26,SUFU,FAM76B,RING1,SPMIP6,TCOF1,RPS14,ZBTB18,SNRPD2,UBE2D3,MED27,MCMBP,WBP2,API5,FBXO11,TBK1,ODAM,TAF2,CMKLR2,BECN1,MSH6,MED30,MXI1,MAGEC2,MED4,SNRPN,TNFSF13,KRT8,RPS9,FAAP100,CACYBP,MED29,GLO1,RBMX2,NICN1,ZMYND11,RNF8,FOXC2,STK16,SOD1,INPP4A,FOXP3,IMP4,PRPF4,NUP62,IRF1,PPIG,STAC3,XPO5,CDCA7L,AP5S1,RIMOC1,LSM8,DRG2,POLR3H,ANAPC15,RALYL,TCEA1,THOC3,CD63,CGRRF1,MPIG6B,ATPAF2,PPM1D,DPPA2,SMARCE1,SAP30,KLC2,RNF126,RPS29,GIT2,IFI35,RFXANK,CDK1,TRIM24,PSMD6,FZR1,MTAP,SNAPC3,EGR2,ABHD16B,TFDP2,STAT5A,MACROD1,CCND3,EIF3E,DKC1,DCP2,CXXC5,CREB3L4,GJC1,SIRT7,EIF4A3,PSMD10,THOC1,CTSK,KLF3,ZNF609,YIPF5,AKR1B1,MNAT1,BARX2,EIF4E,TAF7,PRMT5,CLP1,KLF4,CDK5R1,RPS15,HMGB1,APBB3,ZC3H14,CTBP1,NDUFS3,CCDC106,TRIM6,TENT5C,NR1I3,ZNF692,RPA3,SKIC8,ANP32A,MAD2L1BP,OSGEP,MBD5,DHX9,PIP5K1A,PYDC2,PPIH,UBE2I,PHC1,ZBTB38,BTBD10,TCF21,RBBP7,NUP50,E2F6,SUMO2,SLA2,KLHL7,MED13L,TP53,HLF,CTSC,HMGA1,COPS7A,TRIM8,PTPN5,RPS20,GEMIN8,H3C1,CTDSPL2,MORC4,NR4A2,CENPM,ASCC1,TXNRD1,CTNNB1,DUSP10,RNF187,SNAP23,CXXC1,CCNH,NCBP2,IRF7,LDB2,UTP25,MCL1,SRSF4,FBXO7,DENND2D,TRIP4,SRPK2,POLR2F,E2F4,PDE9A,LSM2,APEX2,CPSF4,CTDSP2,LIMD2,EGR1,SPC24,DBR1,SNAPC2,CDC7,RETREG1,HNF1B,JUNB,PPP1CC,NAA15,CACNB4,DLX1,MRPL36,SUPT7L,MIF,RBM42,CCAR2,JADE1,LIPA,UQCRC2,NEK2,JAML,NAA35,MBD3,EGLN3,APOBEC3H,RPSA,PSMB1,DHX38,MYBL2,AIPL1,LSM4,BAG3,PPARA,PPWD1,NOVA1,PSMC3,HIRA,TERC,KANSL3,SMAD2,SCNM1,UBE2L3,DYRK1B,NGRN,NEK7,MPHOSPH6,RAB5A,TIMM17A,ELOF1,TNFAIP8,TRIM27,EIF2AK2,DXO,PQBP1,RAPGEF5,CCNB1,NUFIP2,FBXO3,FOXP1,KIN,SKAP2,PYCARD,TRA2A,MEF2C,BOLA3,FAM222B,BNIP3L,ARHGAP15,POLR1H,SMUG1,RPS26,MED11,RIOK2,ZC3H11A,THAP1,FAM193B,SRSF8,MRPS18B,FGF1,PSME2,RPL27,SRSF7,ILF2,TAPT1,RRP7A,IRF2BP1,TAF5L,ADRM1,CREB1,USP39,EIF1AD,DTL,IK,CDKL2,TMEM179B,RBM3,CDKN2D,NFE2L2,ZNF451,RUVBL1,CHTOP,NEDD8,CEBPG,PHF13,EXOSC3,GTF2F1,MDC1,HOXB8,ZNF22,FRMD8,CUL2,TRIM22,EDF1,RFC2,INO80C,NXT1,RADX,CDC23,PRDX3,DRG1,TNRC6C,NONO,DUSP26,PSMA2,SNRPA1,GIMAP2,POLR3B,IPO8,MAD2L2,PSMD1,PSMD4,CPSF2,TRMT61A,RPS4X,HYPK,RXRG,CBR3,SP2,NFKBIL1,FTSJ3,H2BC17,HADH,TMA16,SETD5,PHF23,NCAPG2,POLR2B,GTF3C3,SAP30BP,IRF3,ARPC2,AATF,AMT,PWP2,HNRNPAB,MAPK10,KRR1,TOPBP1,FOS,HEXIM1,RFX5,THOC6,ZNF687,SMAD9,FERMT2,CBX3,POLD4,PML,PSMB4,LRIF1,ISG20,TSNAX,GTF3C4,EID2,DNAJB4,NDUFB5,METTL14,HDAC5,RERG,VTA1,ZNF622,ZMYM2,TOP1,RAD23B,AFTPH,SHOC2,HNRNPD,GTF2H2,RPS2,PPME1,ZNF473,CLPX,PTEN,TAB2,PPP1R12A,PGR,ATF1,NFYA,LSM5,BTG1,ABHD17A,PAPOLA,RPS27A,TAF10,CCT8,DPY30,PHF1,SMAD1,PYM1,MIOS,ANAPC11,CWC15,PTPN11,LDOC1,CHAMP1,PSMB6,USP15,SPOP,UBB,SYVN1,PROX1,RUVBL2,SIAH2,H2BC11,OLR1,ISG15,CHMP1B,ZBTB16,RLIM,ELOC,MAP2K3,MED17,BAP1,SLC39A7,SNRPE,HFE,EHBP1,TWIST2,MRPS26,PRPF19,BRD9,ID4,HSP90AA1,CTNNBL1,RPS11,FOXN2,MSX2,RFC4,PTPN4,GON7,AKAP8L,CDKN2AIP,MYO6,EYA3,CCAR1,CDC26,POLE4,ING2,MXD1,POLR2I,APOBEC3A,C1D,CCND1,CCDC22,SETD3,MITF,SF3B4,XPOT,PMM2,DNAJB6,CAPG,H2AC6,COP1,PRPF31,RNF7,DNTTIP1,MYCT1,ATP6V1D,ELK4,SNRPA,UBE2V2,KMT5B,MCM3,HSPB8,LMNB1,TXNL4A,CNOT7,HNRNPA0,SUPT5H,BANF1,BCCIP,TRA2B,LDB1,RCHY1,ENY2,RAN,CBX5,POLR2D,KLF9,CREB3,INTS10,NXT2,PSKH1,PEG10,RBM18,NUDT9,RPS17,RPS5,PDHB,HBP1,HRAS,PRDM4,EMG1,HOXB1,HILPDA,NUP153,EXTL2,RBM22,ZBTB39,NDUFS2,CNOT2,PSMC4,STAP1,BUD23,HNRNPL,RPS6KA4,ABITRAM,UBE2N,SGMS2,SERPINB10,SUMO1,POMT2,SF3B1,ZNF326,CHST2,EP300,MCOLN1,MAF1,MGMT,PLAGL1,CDK9,NAB2,TESK2,UHMK1,ADK,FCF1,NR2F6,ZBTB33,RBM7,ATXN1L,PPP4C,CASC3,ADD1,CPEB1,CNDP2,SLU7,CD2BP2,RNF113A,CD2,ADH1A,DDX39B,FBXW7,CIART,CAMK2G,GCHFR,TSEN34,SERTAD2,PHB1,DNAJC2,GPC1,HNRNPDL,CCDC174,HCFC2,RMI1,MEF2A,UBE2S,GTF2IRD1,SUB1,FOXD3,GOSR2,NAA11,DNAJC7,RMI2,IFI16,TFPT,TP53INP2,RPRD1B,GTF2A1,PAX9,RERE,ZBTB45,HNMT,H1-1,FEM1C,GATAD1,FYTTD1,HDAC11,ZNF436,RPRD1A,SMURF1,SMAP2,CD274,PPIL4,PRCC,DLST,PSMD14,RBM5,DYRK1A,UBL4A,OARD1,TADA3,PAGR1,AIP,MYRF,FBXL4,KPNA6,RPS7,PLA2G15,PRKD3,UBE2D1,GFI1,CMTR1,MED10,RPP25,H1-5,RBBP9,BHLHE40,PPARG,PSMC1,RPAIN,ABCF1,GGPS1,FAHD1,TESC,PCBD1,POLR1B,UQCC3,TULP3,RPGRIP1L,MDM2,RPL23,NR0B1,GCFC2,UBE2W,AURKAIP1,WDR82,CBX7,LMO2,CDC20,PRIM2,CCNA2,EID2B,NABP1,GTF2H5,HSP90AB1,ARL14EP,FUBP3,TLE1,CAND1,TREML1,SDCBP,XRCC5,DCAF16,SRSF10,E4F1,FOSL2,EZH2,PSMB2,HR,SMU1,DEK,SLC25A10,MED22,RTCB,RGCC,ALKBH5,H2BC9,EIF2D,HSCB,RBPJ,TFE3,OSBP,PHF12,MORC2,PRPF18,P4HA2,PIR,CDK6,ACTB,ASF1A,ZNF24,WDR20,IRF9,AQP3,PPP1R8,ZNF207,GTF2E1,DNAJC8,NRBF2,TAF1D,CRTC2,STAT1,SIX5,RGS10,DCLRE1C,POP5,DCUN1D1,NKRF,SMC4,RACGAP1,MED31,UPF3B,TRIM34,THAP7,MYC,SKP1,COMMD5,ZBED1,MACROH2A1,CGAS,PRMT6,UQCC2,SOX3,MAEA,KPNA1,STXBP1,ZHX1,PSMA4,OIP5,LITAF,CDC16,POLR2G,GTF2I,NOP58,HPGDS,SART3,PTGES3,ABCG2,MAPKAPK3,VEZT,TXN,MAPKAPK5,MAP1S,ST6GALNAC3,ZRANB2,ZBTB17,CSNK2A1,PSMA6,UBL5,OAZ3,SNRPB,PPIB,HUWE1,CDC40,NOP16,MED9,POU5F1,THUMPD1,SMAD4,UCHL3,CFAP68,PRKACB,CIPC,RNF146,UNC45A,MRPL52,NHEJ1,STK11,SRP54,COIL,RBM15B,PAXX,DGCR8,PEX3,PAX6,HNRNPH3,PEA15,OAS1,POLR2L,NDUFB6,SURF2,TSN,ZGLP1,SP1,LPXN,SPIN3,RANGRF,RIOX2,BACH1,KDM2A,MAFG,DDX46,FAM50B,MLH3,ZMAT3,UAP1,EED,TSEN54,RUNX1,NGDN,UBE2A,PSMB10,IRF2BPL,TAF11,SH3GLB2,RAG1,PSMA1,CSNK1A1,NOP53,UBE2M,MAX,SPRED1,NOTCH2,ING5,LYAR,SMARCB1,RFC3,TSPAN15,ACADS,BABAM1,MKLN1,ATF4,CUL3,APPBP2,CSE1L,FAS,NR1H2,ELF1,PIP4P1,GTF2H4,SLC30A5,GTF2F2,TADA1,NLRP1,MLLT11,PCSK2,UBP1,FAM20B,SMN1,POMP,APEX1,PSMD3,TAB1,RIT2,SMAD3,BUD31,MTF1,SNRPB2,RTRAF,SPATA2,PCGF2,POLDIP3,CDK4,OAT,NHP2,ARPP19,DDX42,NEO1,CAVIN2,PSMB5,ZMYM3,PRKRA,H2BC14,ZNHIT1,SOX9,MAP2K6,HNRNPH2,BATF,NUP37,SLC13A5,ALKBH3,USP16,TDP1,UTP6,RPS28,BRMS1,FBXO32,KLF12,H2BC1,RDM1,FAF1,OPTN,SMARCD3,PELP1,WDR5B,WDR3,CPT2,ARL2BP,MAPK4,CLIC2,HNRNPC,NFKB1,USP2,TGIF2,KLF1,HSPA8,FEM1B,CSNK2B,SPHK2,PSMB9,CSTF3,NPM3,POLD2,SNRNP27,DUSP18,PRMT2,MAP3K14,ZBED4,PARP2,DCAF4,BAZ1B,SHMT1,UPRT,PPP1CB,RRN3,PRRC2A,SHPRH,CHCHD1,GEMIN7,CDKN1B,NDUFAB1,MEF2B,EEF1E1,HINT1,CIRBP,UBLCP1,SYNCRIP,ORC5,CBLL1,PRELID1,COMMD9,RNF208,GABPB1,PPIL3,SNRPD1,TRMT10B,ZNF330,MAGOHB,BAHD1,SF3B6,SNX20,FKBP4,GINS4,TOPORS,KLK6,LYPLA2,PRKAG1,SRSF12,PHF7,FAM107A,MZT2B,MED21,DPEP1,TRIM21,NR1I2,MTG1,ADH1B,HDAC6,TCEA2,TP53INP1,DPH3,DVL2,MINDY3,RNF40,IP6K1,ANKRD10,MSL2,SP4,CDK12,IMP3,HSBP1,LSM3,PTHLH,MRFAP1,PSME1,SNRNP48,SUPT3H,NAIF1,STAMBP,VDR,SNAPC1,ZHX3,COPS4,MTA3,TRMT112,IER2,CPSF1,NUP35,GINS3,KPNA2,SLC35A2,PHAX,GRPEL1,EPOP,RPS13,DUSP6,LGALS3,INO80E,SLX1A,BCL6,RB1,BRMS1L,SAP30L,TRIM11,CDK7,TCEAL7,DHX15,TMEM70,STUB1,OPRK1,PARM1,THRAP3,WTAP,SRI,LUC7L3,SLC7A14,PIAS1,DCAF11,UTP15,TCIM,BUB3,NKX3-1,ALKBH2,OGG1,TSPAN5,DMAP1,GLRX2,LSM10,HIKESHI,NLE1,TTC4,HNRNPA1,PCNA,SLC8A1,RSL24D1,SNRPG,THOC2,AKAP17A,DYRK2,COMMD8,IRF8,SEC14L1,ZBTB42,SSRP1,RPL26,TNKS,CRYAB,COX4I1,CENPP,TFIP11,MFAP1,ELK1,PLCB1,NOC4L,ZBTB2,FABP5,PCLAF,GNAI2,CFAP20,RPL8,MCM6,RBIS,IRF2,DDX1,SRSF2,APTX,MCM8,EID1,RPP14,COPS5,ESR2,INPPL1,PSRC1,SUMO3,SSU72,JUN,TENT4A,LORICRIN,ATF3,RBM27,RAD21,CETN2,POP7,NDUFB4,CDKN1A,FKRP,RRAGA,CRABP2,MAGED2,MPHOSPH10,NBN,HOXC4,MEAF6,RORB,AGO1,CSTA,CENPW,MORF4L1,MTDH,ELK3,TOLLIP,RPS23,GADD45A,CREBZF,BPNT2,LANCL2,SAMHD1,PPM1G,TRIM68,PHF21A,SURF6,AKIP1,ZBTB14,SQSTM1,MYG1,YWHAZ,NFYB,BMPR2,DCK,SMARCA5,IL15,GRAP,EEF1AKMT3,PAK6,BCL9,POGK,GTF2B,PRKX,TAF9,PLPPR1,TFCP2,STX6,VPS72,PLEKHA8,COPS2,TNIK,NDN,SIVA1,STK24,DCAF5,XAF1,ATP6V1A,LIG3,H1-10,AKT1,CDK8,NAB1,SNRNP70,UBE2V1,GABPA,PPP1R10,POLE3,NCOA5,PSMC5,CMPK1,COPE,CDC73,TERT,FAM20C,CTDSP1,ZNF593,NUDT16,DROSHA,SOX2,CMAS,DCUN1D3,NIBAN2,PCGF6,PIWIL4,PRKCA,NSMCE3,BRCA1,ZCRB1,ABHD5,SETD7,SPRY1,ZCCHC9,DAG1,RPAP2,HP1BP3,RPS24,ANP32B,TRIM5,PSMB7,CDK2AP2,SLC35F6,CSTF2T,SMAD5,ORC6,WDR77,RPL27A,ALYREF,PPID,EXOSC4,TRIM45,RPS12,TCEAL1,ARL4A,ID1,FBXL3,CREBBP,CENPL,MRPL10,TRIM37,PRM1,GTF2A2,HNRNPF,ANAPC2,METTL21A,ZNF322,ANAPC4,SIN3A,GNAI3,LMNA,COPS7B,KDM1A,DMTF1,TNFAIP8L3,POLB,FAM118B,RARS1,NTMT1,DFFA,SATB1,MTA2,SUV39H1,HECTD1,NFKBIA,PSMD7,PRR13,MAD2L1,KDM4B,ARGLU1,XBP1,PPP5C,ABHD14B,JAK2,WDR12,LCMT1,SRC,NDC80,EXOSC8,DDX23,STAT2,SEC13,METTL22,RPS10,HDAC3,PAAF1,GMNN,RCL1,RFC5,SNRPD3,BRAP,ARFGEF1,DAPK3,POLL,VIRMA,PRKCB,CRKL,PFKFB2,HNRNPK,STAT6,STN1,STX12,INTS12,SRSF1,RBBP8,LRWD1,XPO1,LYPLA1,NKAP,PSMD12,FOXA3,PSEN1,KCTD10,SF3A1,PPP3CA,PSMA5,CCNY,SNRNP40,ENC1,SMDT1,SDHB,LSM6,STK4,ZNF174,RFXAP,FAU,RPF2,TOP2B,RBM12,CDK20,IGF2BP1,CKS1B,S100PBP,TXNRD3,NRDE2,EAF2,WDR55,NUP42,AKT2,KIF2A,RNF34,ANAPC16,NFE2L1,SETD9,CDC5L,NOB1,PNO1,S100B,MACROH2A2,HEXIM2,SNAPC5,DDX39A,NT5C3A,USP3,PSMA3,MFAP3L,CSNK1E,SUGP1,CITED1,IL2RG,RAD1,NOSIP,SAP18,ZBTB25,H2BC12,CCDC92,IVNS1ABP,RPS16,NUPR1,DHX16,PCGF3,EZH1,TRAF2,HINFP,RNF20,CEBPE,UBN1,ACTL6A,BAALC,PRKAB1,ARMC8,UBE2B,CBFB,FANCG,ECD,MIDEAS,CGGBP1,USP13,POLR3F,PIP4K2C,DNLZ,BIRC5,SF3B5,POLR2C,RPS3,DCTPP1,DSN1,SNIP1,MCM4,IRF4,DR1,VRK1,HEY2,GRAP2,RBFOX2,MECP2,POU1F1,HCFC1R1,DNTT,TIMMDC1,SPR,WRAP53,HNRNPA2B1,CEP19,ADRA1A,ERCC3,ZBTB6,MPG,CCDC86,ZMAT2,NMRAL1,NMI,RSRC1,DDX5,NFE2,NUF2,OLFM2,CFDP1,PSMB3,SUPT4H1,TRMT6,SDHAF1,VPS54,UBA52,TASL,SMNDC1,HSPB6,PLSCR1,MAGOH,CDK5,RBM34,NR2E1,MCPH1,TIA1,UFD1,GTF2E2,ZMAT5,WBP11,YAF2,WEE2,RP2,UBE2E3,RPP21,CTNNBIP1,SNAI2,SERPINB9,EXOSC1,POLA2,GJA1,RBM17,H2AX,AR,EWSR1,SPATS2L,UGDH,SENP5,EGLN2,GID8,PARP11,DUSP3,MSX1,CPNE1,RBBP4,FEN1,POLR3GL,NUCKS1,AGAP2,KHDC4,SMYD3,PAK5,GRSF1 |
| 1.034e-17 | -39.11 | response to stress | biological process | GO:0006950 | 3388 | 1205 | 18204 | 5365 |
SRPK2,NOTCH2,CRIP1,POLB,IL1A,TGFB2,FCN2,CLPB,METAP1,GTF2H5,FGF10,DEFB116,PCNA,ZBTB38,NUDT2,TF,NCK1,GCLC,RAP2B,IRF2,SOX2,NFKBIB,GSTM2,TTC4,PEX13,C1QC,HSBP1,AP5S1,VPS4B,DDIT4,FOLR2,JCHAIN,CCL20,WFDC13,CREBBP,FUNDC1,ATP2B4,MIR200C,NABP1,HPS6,SMAD1,NLRP6,H2BC11,EDEM1,CD151,IRF7,USP14,CRYGD,MACROH2A1,FOSL2,LTA,SLC25A24,PAGR1,CHGA,MAP1LC3A,SHC1,SUMO1,RNF126,CRHR1,IDH1,OAS1,GPX4,TRIM22,MIR20A,CCL21,PRCP,CIRBP,NFE2,TNR,MTF1,FAM3A,CTNNA1,FEN1,MTARC2,BAZ1B,IFI35,ATP1B1,ATP1A2,CDK7,PTTG1,HSPE1,GSTM3,FAAP100,MIR106B,G3BP1,HNRNPA1,HCRT,MYC,IER3,MIR126,SLU7,HSPB2,FAF2,DAPK1,ZSWIM7,IFNAR1,HSPB1,PRDX3,TDP1,APOBEC3G,APOBEC3D,BPIFB3,CD83,PELI3,MOV10,CDK1,RPS6KA4,NDUFA12,HSP90AA1,TNFSF8,WDR45,UBE2A,RBBP8,PRDX4,IFNB1,TRIM11,CAV1,DCTPP1,CDIP1,HTR1A,CDKN2D,ZYX,BLOC1S3,ERLIN1,FKBP1B,HSP90AB1,RAB1A,TAX1BP1,MEF2C,MSRB1,MSTN,CAV3,POLR3H,IFIH1,SLPI,ZMPSTE24,IRF9,GFI1,ALKBH5,SLC38A3,BRCA1,SERPINB6,RNASE1,APOBEC3F,POLR2I,CLDN1,CD4,RNF113A,TRIM26,PTN,HBEGF,PLPP6,PSEN1,ARL6IP5,RPS27L,CCR3,DDRGK1,ADIPOQ,RBBP7,RAF1,ROCK2,IL10,PTGFR,NMBR,RFC5,CBX5,CCM2,TRAF2,CX3CR1,DBH,FBXO31,VAMP7,LY96,TRIM6,CINP,RPS3,CD1D,HMGB1,GPX6,MBL2,INO80C,KLK6,EPHA2,PTK7,MPIG6B,H2BC1,BCCIP,OR2H2,CAB39,CXCR4,AGER,PYCARD,HRAS,BATF,RHOB,MAPK10,CXCL10,TNFRSF14,VAMP2,SH3GLB1,RFC4,HSP90B1,USP16,APOBEC3B,CIDEB,NKIRAS2,SPINDOC,ADO,H2AX,GPX3,CGAS,DAP,TRIM23,OGG1,CFTR,NEFL,LMAN1,DDR1,SCN2B,ACVR1,RAD23B,TBC1D5,SLC29A1,POMT2,F2,CCR2,EDEM2,PLSCR1,HSPB8,PSMD14,UFM1,CXCL8,RRAGA,IDO1,ERCC3,SPAG11B,CYGB,AZI2,APEX2,IL21,CLEC7A,VPS4A,MIR34A,IL13,UBE2D3,H2BC12,P2RY1,VASH1,PRDX2,COMT,CHMP1B,ADORA3,ADORA1,SCAMP5,BPIFA2,LXN,SELENOP,CCL11,MICB,HUWE1,DCLRE1C,CCL8,PTPN11,TFPT,POLE3,NONO,EYA3,DDIT3,TRIM27,FKBP10,LRRC8A,SERPINA3,NR4A2,RAD21,MNAT1,EPO,SLC6A4,EGR1,CHCHD4,GAPDH,IKBKB,MYRF,IL34,FANCG,CNOT7,EDEM3,FZD6,YTHDF2,FBXO22,PYCR1,ITK,AK3,CHRNA7,TLDC2,CHRNB2,EZH2,TSPO,BTG2,UFD1,GABARAPL2,MIR193A,STK24,F11R,PRKCQ,SESN2,JAML,SP1,LIPA,PPARG,CCNA2,PTGER4,EP300,CERS6,RNF103,PDCD10,RFC3,BOK,NPC1L1,SLC1A1,NPR2,CTSK,SHLD1,HYAL2,BACH1,SLC1A2,CCL24,TMEM106A,GPT,GPX1,ZMYND11,LMNA,UBE2V1,UBE2V2,CDC7,UBE2G2,RNASEH2C,PYCR2,SERPIND1,MIOS,NOP53,NDNF,PDIA2,GABARAP,ISG20,MT1E,UBXN6,SELENOS,INO80E,SMAD4,TANK,BCL2L1,MORF4L1,PTEN,JAK2,STXBP1,LYZL6,BST2,USP3,STAT1,TIRAP,LACC1,CRY1,ASF1A,DEFB114,DERL1,BAD,RAB27A,SMCHD1,CD34,CREBZF,HPF1,ADRB3,AATF,CDC42EP2,ODAM,NRBF2,EIF2AK2,CD14,POLL,IL22,SEC61B,ATP5IF1,MIR221,STK26,PLAA,CARTPT,UBE2N,MYO6,FOXP1,CXCL9,YWHAG,STOML2,RNASE6,FGR,UBE2E2,POLR3B,RNASEL,IL12B,UBE3A,MX2,PI3,RSAD2,SERPINA1,MIR107,BGLAP,CAMLG,JUNB,TRIM34,TOP3B,JUN,CHCHD6,MORC2,LDLR,HSPD1,VDAC1,CBX3,DMAP1,PPP4C,MT1X,PRELP,GPX2,ADRB1,NEUROD2,PPARA,IFNGR1,FLOT1,RPL39,VEGFC,GPR37L1,SLC1A3,LYAR,CHMP2A,SIN3A,TSPAN18,IFI27,BCL2A1,AQP2,MLH3,APTX,RRAGB,VAV2,MIR210,PMAIP1,POLR3F,CD36,LIG3,RMI2,POU5F1,PCK2,RWDD1,EXOC1,SYNCRIP,LEAP2,RGCC,UBE2B,JAK1,PROS1,AQP4,LILRA2,GPX5,MSX2,CD9,ECRG4,CXCL3,VWF,IFIT2,STC1,CDH8,SLC7A11,ATG16L1,SARM1,SMAD3,CRHBP,POLD2,TAF9,TUSC2,DEFB115,KLRC2,KMT5B,TMIGD3,TEX264,TRIM62,TFRC,SELENOK,CLU,RINT1,TMIGD1,WDR83,RALB,CCL23,OTULIN,KLF10,NKX3-1,ATF3,AKR1B1,FCGR2B,DNAJC4,BMPR1B,TASL,FOS,PSPC1,CHI3L1,RPAP2,PML,MT1M,RNASET2,MYL12A,ARG2,EIF2S1,NFKB1,CRADD,KCNJ8,TERT,CCL4L1,PLP1,ALOX5AP,CD38,CD2AP,THBD,ZDHHC16,TRAF6,GADD45A,TICAM2,NDP,HP1BP3,TLR10,NAE1,MT2A,PACRG,CCL19,TMEM74,TLR5,SFTPD,ACAT1,NINJ1,CTLA4,ADGRE2,GNB1L,MACROD1,TMEM117,DTL,MEIOB,GPR37,FAU,SERINC3,TAB2,RNF121,IFNG,ARMT1,HBA1,PRKRA,TMEM45B,LGR4,EXT1,KCNJ11,PNMA1,MGARP,SST,FAM162A,NRDE2,DAG1,MSRB3,SRC,SMARCA5,SERPINH1,TFPI,PSEN2,HEXIM1,COTL1,PHB2,ZNF175,ZMAT3,TRIM21,MCM3,ATF4,TM9SF4,RNASE4,LEP,SQSTM1,MT1A,PRMT6,DNAJB4,NFE2L2,TICAM1,MIR181C,MIRLET7I,MECP2,LILRA1,BMPR2,SEMA7A,PDIA6,BNIP3L,SMUG1,UBASH3B,PQBP1,IRF1,AFAP1L2,C1GALT1C1,MAN1A2,PGK1,TLR8,IFI16,TFIP11,TOMM7,CTNNBIP1,BPIFB1,NBN,FBXO44,ACTR2,EIF2B5,DPEP1,TMUB2,ALB,CD209,PLD3,MAP2K3,KLHL15,SESN3,DEFB1,GJB2,LIAS,EIF2B3,KCNMB1,JAGN1,IL18BP,TRIM8,RFC2,RMI1,MSL2,COL3A1,CXCR6,VAMP8,RPA3,DHX9,SDF2L1,GLRX2,UAP1,CCR6,STAT6,RNF8,ISG15,FAM8A1,CCR7,MCM8,CXCL1,RNF167,CST11,ADRB2,OSER1,HCFC2,IL5,TLR7,CDC5L,DHX15,KDM1A,OS9,GAD2,TRIM29,PRPF19,MAP3K14,CCR1,MAP2K1,HDAC5,MRC1,CCS,IRF8,NUCKS1,FCGR1A,REG1A,CCDC92,DHRS7B,CYBC1,HNRNPA0,EXOSC4,CPEB1,CSNK2A1,BAG3,ERO1A,CCR5,OLR1,STAT2,CBL,BECN1,TOPORS,HBB,LRRC8C,BANF1,DNAJB9,CYP1A1,UBXN10,RAB3A,CST3,KCNB1,CCL5,CNPY3,TRIM68,TLR3,DYRK2,DEFB124,PTGER2,SLC6A2,CCL17,RCHY1,CSNK1E,FLCN,SFRP1,IGF1R,CDC42,PPIA,FZR1,PLA2G4B,CRYAB,NUPR1,NDUFS8,MIF,CCL3,REN,BCL10,SHPRH,IL12A,SCG2,SOD3,ELMOD2,MAP1LC3B,LILRB1,CSF2,IRF3,HEY2,STX8,RNF34,SETD7,AKAP1,CHID1,NCR3LG1,THG1L,TYROBP,MAVS,F9,ING2,CDKN2AIP,RUVBL2,MDC1,HTRA2,HSPA5,SOCS5,IL20RB,TACR1,MYD88,GTF2H4,IL4,CD46,AQP3,FXN,TXNRD2,NLRP9,MIR146A,NUDT1,DGCR8,ACTB,HMGA1,DEFB121,TNF,VAPB,EXD2,TMUB1,CX3CL1,GINS4,XCL1,MUL1,RBPJ,TEX12,FCGR2A,ATP1A1,PDE12,RUVBL1,PDIA3,CSRP1,ERLEC1,PHB1,RPA2,TOP2B,FGF7,DNAJC10,STUB1,PLAC8,BCL6,CXCL12,HFE,TOPBP1,KCNMA1,TBC1D24,KDM2A,HINFP,RNF5,FBP1,PCLAF,PLG,IL1RAP,DUSP10,FOLR1,LSM14A,CDK9,CDKN1A,CASP4,ILK,PTGER1,RNF152,CCL18,MRGPRX1,GNG7,CITED1,LRRC8D,NLRP2,PPM1D,CHST2,CXCR3,MIR214,MIR17,CCL25,NLRP3,CEBPG,CLDN3,NHEJ1,SLC25A27,AIF1,ABCF1,TIFA,IRF4,GGCX,BRINP1,MPG,TAC1,SDC4,MDM2,LYZL4,FADS2,PSMB5,VCPIP1,TP53,MAEL,TNFAIP6,SOD2,ENDOD1,MCM4,ASCC1,ITGAV,MSMP,TMEM33,TRAM1,PCGF2,MGMT,UGT1A1,MIR26B,RAD1,LARGE1,LAMB2,PTPN1,CIAO3,HSPA8,KLF4,CLCA1,PIP4P1,TOR1B,ALKBH3,SEC14L1,HMOX2,TLR4,IFI6,CYB5B,LGALS3,RNF139,ZNF668,HMCES,CYP27B1,RBCK1,TRIM15,SDHAF4,MIR195,FAF1,GABARAPL1,ATAT1,EIF2B2,DROSHA,NQO1,PLGRKT,CDKN1B,CDO1,IMPACT,TRIM52,SUV39H1,NREP,TNFAIP8L2,IRAK4,CHMP5,FCMR,CXCL13,UFL1,CHMP4C,SCFD1,SLC15A2,PAPSS2,LYG2,SGTA,APOBEC3H,F10,NFKBIA,IGF1,ROMO1,UBE2W,PPP1R11,DIO3,UCP2,FBXO9,CALR,SIRT7,TNFAIP3,MAP1B,AGTRAP,BAK1,TXN,GSTP1,MT3,CXCL11,CREB3L4,KICS2,OXTR,CEBPE,ELAVL4,DEFB129,ITGB5,WNT7A,PPP3CA,KCND2,AIFM1,AKT1,DYRK1B,DELE1,TGFB3,IL1B,NCR3,IFNA13,AGR2,TLR6,RPL26,ITGA2,FKRP,PPP5C,USP46,FGF1,B4GALT1,ACP5,NRP1,PCSK9,CDK5RAP3,SYVN1,EGLN2,PRKCE,PAXX,ACER3,MIR448,KRT8,LCP1,RPL13A,CD59,XBP1,TERC,TOLLIP,FAS,KIT,FLRT3,TUBB4B,PHF1,TSC22D3,CCND1,MSH6,MIRLET7B,KLRD1,SOD1,SUSD6,MACIR,DNTT,RAB23,IMMP2L,SLC2A8,POLD4,GLTP,G3BP2,MIR223,MCM6,MMP14,TREML1,ERLIN2,FCER1G,DDX1,GP9,TP53INP1,ENPP4,RTP4,TRAF3IP2,BAX,EIF4E,IL6,LAMP2,NDST1,PYDC2,ACAA2,MMP9,GNAQ,CETN2,IFNA10,MIEF1,CHMP1A,ADIPOR2,VPS26B,ACTL6A,PPP2CB,MX1,MPV17,FOXP3,MATR3,TMED1,OXSR1,MIR130B,BVES,PRNP,TENT4A,SLX1A,DAPK3,CXCL14,MAD2L2,PAX6,RIGI,SAR1B,MGME1,CLEC6A,TXNIP,EDNRA,NMI,OPTN,SRXN1,UCN,CHMP2B,CDC42EP4,BABAM1,HP,GNL1,TLR9,ATG7,IFNK,TNFRSF1B,HDAC3,WFDC5,FGFR1OP2,SH2D1A,MCL1,HM13,DHX16,SELENON,SFN,IFNA2,JKAMP,DNAJB2,DNAJC3,CD2,DCUN1D5,LGALS8,SLC2A1,CERS2,RNASE9,PARP2,TRIM32,GPAM,GLUL,ASIC1,RLIG1,KBTBD6,BIRC2,SLC23A2,YES1,EGLN3,LACRT,SYK,CH25H,HILPDA,NLRP1,CCR4,OMG,DERL2,TMBIM6,RAB14,CD40,FBXW7,PRDX6,POLDIP2,FOXA3,S100A8,NOG,PRR5L,HDAC6,SGF29,STK11,CREB3,APOBEC3C,TRIM5,CCAR2,MAP2K6,NPPC,NGB,IL2RA,IGF2BP1,DUSP6,H2AC25,CCL2,CHCHD2,SEMG2,KIN,MAPKAPK5,NUP62,TUBB,DRD1,SNAP23,APOBEC3A,TLR2,RARRES2,G6PD,SLC12A2,CYP1B1,DPP4,P2RY11,VAMP3,PICK1,VPS54,TBK1,BPGM,XRCC5,PPIF,STAT5A,TCAP,PIK3CA,CD47,IL17F,F7,NDUFS2,TCIM,APEX1,P2RY12,OARD1,STAU1,CAMP,GNPAT,CHST1,GPX7,GTF2H2,PRDX1,IL18,NT5C3A,ELK3,WRAP53,MORN4,TRIM35,HIKESHI,CD58,ACO2,TFEB,MIR140,REG1B,PIK3CG,INSIG2,FASLG,CD40LG,HSPB6,ABHD2,TLR1,NSMCE3,NDUFB4,RRM1,VRK1,IL23A,ALKBH2,SLC38A2,VEGFA,SAMHD1,TIMP1,LYZ,CCDC47,PIK3R1,TRIM10,NR2E1,SETD4,NR0B1,CUL3,PIK3R2,VKORC1L1,SSRP1,TERB2,IPCEF1,CCL1,YWHAZ,SLC52A3,NDUFAF4,OPRK1,SERPINC1,CAPN2,FZD4,GORASP2 |
| 1.138e-17 | -39.01 | FUS (FUS RNA binding protein) | protein interactions | 2521 | 732 | 311 | 19454 | 5460 |
SLC25A3,MFAP1,PSRC1,USP39,PSMB7,WDR77,MIR106A,RPS5,MIR363,HSP90AA1,YWHAZ,BRCA1,PDE4B,MIR98,CUL2,PYCR1,CUL3,SNRPB2,PRRC2A,MIRLET7D,ACTB,TUBB,RBBP4,RPS9,SNRPD1,SNRPD2,RAN,EIF3K,CPSF1,SNRPE,POLR2C,EZH2,NUP153,SMCO3,SRSF4,PSMD12,TNF,SRSF7,PCNA,HNRNPA2B1,TRIP4,SLC25A5,HSPD1,LYZ,MIR1-1,HNRNPD,TRAF6,DDX23,TRA2A,HNRNPA1,PRPF19,PDIA3,PRDX1,NUP35,DHX15,PPIA,SRSF10,CCAR2,MIR141,RPLP1,HP1BP3,MIR7-2,PHB1,FOLR1,RPL9,THOC2,TTI2,HNRNPH3,METTL14,HSP90B1,PICALM,TOX4,LMNA,MIR1-2,ATG16L1,SAP30BP,RPS14,SF3A1,SS18,MBD3,PIK3R2,RPL4,MIR7-3,DGCR8,SQSTM1,PPIH,MIR34C,MIRLET7I,MIR205,SIRT7,RPA3,CDC73,CA2,MIR145,NONO,DNAJC8,TUFM,PPP1CC,ATP5F1A,RUNX1,SEC13,VIRMA,ARMC6,LDHA,ACAT1,UBE2I,ALB,RPS20,RTRAF,EIF4A3,TUBA1B,ENO1,MIR16-1,CCNF,OPTN,ILF2,MIR20A,MIR17,BCS1L,PGM1,MIR200C,MIR15A,EEF1A1,CCT5,FBP1,MDC1,SMN1,THRAP3,LSM4,SPATA6,EMC2,ZC3H11A,NSDHL,MIR34A,DNAJC7,CRBN,SUV39H1,HDAC6,MOV10,CDK9,MDM2,THOC1,DCUN1D1,MIR25,RCHY1,MIR106B,CTDSPL2,RPL12,PIH1D1,NCOA5,PPT1,STAU1,EEF1G,TRA2B,HNRNPA0,SRSF2,UFL1,DDX5,DDIT3,EP300,SF3B1,HSPA8,SNRPA,DDX39B,MDH1,RPS26,FBXW11,CCT2,CKB,SNRPB,CPSF2,CCNQ,UFD1,BTF3,LDHB,HNRNPC,HNRNPAB,CREBBP,MYC,POLR2B,SNRNP40,ATP5F1B,MATR3,MIRLET7B,ZMYM2,SMU1,PRMT5,SF3B4,ATXN1L,CMTR1,RPL18,SMARCB1,EEF2,TUBA1A,ISG15,MIR222,SOX2,SUPT5H,MAX,HNRNPDL,CCAR1,MIR155,HNRNPF,RTCB,EWSR1,MIR206,MIR9-2,PABPC1,CCT8,TOX,MIR140,HSPB1,MIR221,DDX1,MIR31,AGR2,DDRGK1,F7,CTNNB1,MIR29C,MIR143,CCT7,HSP90AB1,SNRPA1,SNRPD3,TCP1,MIR9-1,FAM98A,HNRNPL,MIR214,WDR82,POLR2L,SRSF1,FUBP3,ACACA,MIR7-1,MIR21,GSTP1,HEXIM1,ZNF326,RPRD1B,RPA2,CFTR,MIR34B,HSPA5,MIR107,MIR29A,RBM22,RNF113A,PGK1,LSM12,BAP1,MIR10B,RBM7,UBE2H,OAT,IGF2BP1,DNAJC10,GEMIN8,RC3H2,SPOP,ST13,NCAPG2,CFL1,PRKACB,MAT2A,AKT1,NAA50,PPP1R10,MAP3K3,EIF4H,INTS12,MOB4,PSPC1,NUPR1,RNF8,DDX42,TP53,STRBP,UBL4A,MIR16-2,MIRLET7C,MEPCE,HNRNPK,KPNA2,CSE1L,NEDD8,DHX9,MIR9-3,MRPS18B,BHLHE40,MIR200A,USP15,SNRNP70,GAPDH,ELOC,COPS5,PPIL4,RBM17,CDC5L,MIR429,MIRLET7G,FZR1,CAND1,MTAP,ARMC1,ALYREF,SYNCRIP,ITK,SSBP1,CD274 |
| 1.224e-17 | -38.94 | protein localization | biological process | GO:0008104 | 1954 | 741 | 18204 | 5365 |
SNAP91,FLOT1,CPLX3,HSPD1,AP1S2,ROPN1B,AP1G2,TNPO2,VPS33A,CAMLG,ERP29,SEC22C,DUOXA2,DPP10,COPE,LRRC4,MX2,MYO6,YWHAG,SFT2D2,CACNG3,EXOC1,JAK1,TSPAN17,GUK1,TIA1,SEPTIN6,DNM2,RTN4,EMP2,ILDR1,SMURF1,SNAPIN,CD36,MLH3,TIMM29,RRAGB,CHMP2A,SIN3A,ASB3,SELENOS,PDIA2,UNC50,GABARAP,RNF128,VPS26A,NOP53,LMNA,PEX26,FAM53B,IFT25,RALA,VPS26C,CTNNB1,SLC1A1,KDELR2,CAMK2G,SNX5,RAB5C,AP1M1,RIC3,ATG4C,NUP153,TM9SF1,NUP50,ARRDC3,SKP1,TOR1AIP2,TIMM8A,H2AC4,SEC61B,CCHCR1,SNX12,SLC4A8,BCAP29,DERL1,RAB27A,TUBA1A,RAMP3,TOMM40L,DVL2,FAM91A1,KPNA6,SPTSSA,STX7,VLDLR,TSPAN15,LRP6,MCPH1,STXBP1,TM9SF4,RAB40AL,LEP,SQSTM1,PHB2,ZMAT3,CDK20,DAG1,SH3BP4,PPID,ANGPT1,C1QL3,MGARP,SRGN,TOM1,CHAMP1,RAB8B,ARL4A,SNX10,SEC23A,STX5,SNX11,NBN,TMED3,SCG3,AP3S2,TOMM7,TRIM3,SNCG,EHBP1,SNX1,SYS1,KDELR1,SEC61A2,TOMM6,GOLGA7,EMC9,MECP2,MAIP1,FBXO7,SNX17,GRPEL1,FCHO2,MACROH2A2,UBL4A,CLU,RINT1,ZDHHC4,TMIGD1,SEC63,CLTRN,NXT2,TFRC,ESAM,SRP14,RILPL2,RAP1A,PHYHIP,GPAA1,CD63,ATG4A,ATG16L1,SARM1,RAB19,RAB35,PACRG,CUTA,NLGN2,VPS16,DNLZ,NDP,CD2AP,LAMTOR1,IGSF11,FGF13,SSNA1,LAMP5,KCNJ8,TERT,NECAP1,PML,SRPRA,DISC1,GDI2,WDR45,MTCH2,CNIH4,SNAP25,SYNDIG1,BTF3,HSP90AA1,INPP5K,HTR2A,CDK1,MARCHF5,REP15,SLU7,FAF2,HSPB1,GOSR1,ZFAND6,TOMM40,ATP1B3,TMSB10,FRMD8,SEC61G,PMPCA,PREPL,CASK,DNAJC19,CD4,AP2A1,PTN,TNKS2,PSEN1,MTM1,EGR2,ARL6IP5,ATG9A,VAMP5,SNX3,TRAM2,SMAD2,CRB3,TNPO3,PLEKHF2,SUPT7L,CAV3,BLOC1S3,FKBP1B,AGAP2,RAB1A,TAX1BP1,NECAP2,TNKS,MCOLN1,CAV1,TOM1L2,ZDHHC24,AP5S1,VPS4B,SNX33,TIMM10,EIF2D,PEX13,TRIM37,TMEM115,EMC2,FGF10,SEC22B,CHP1,HYCC2,ATP1B1,CTNNA1,ARL5B,AP5M1,AIP,SUMO1,PRKCB,AFTPH,CHGA,ACTN4,XPO5,RIT2,MACROH2A1,TTC8,HPS6,EDEM1,H2BC11,RER1,AZGP1,DDIT3,NETO1,TOMM70,CHMP1B,RRP7A,ADORA1,SCAMP5,P2RY1,COMT,VPS4A,SVBP,BCS1L,ARF1,ERCC3,MADCAM1,TMEM30A,FKBP8,SRPRB,GNPTG,RRAGA,CCDC22,RPL23,RAB39B,PAQR3,YIF1A,ANKRD50,DESI1,LIN7C,PPARG,ARCN1,CETN3,JUP,STX12,PGR,GOLGA7B,RAP2A,TSPO,UFD1,TMED5,GABARAPL2,SPCS2,GLE1,RABIF,F11R,RAB32,OSBPL8,EZH2,CEP41,CHCHD4,IKBKB,AGAP1,AP1AR,TRAK2,CNTN2,RAD21,TPBG,SRP54,AGER,RHOB,PLEKHF1,S100A10,TRIM46,EMC6,VPS28,EPHA2,RAB6A,STX1A,CORO1C,MAPRE2,ABHD17A,CNTNAP1,RAB6B,VAMP7,SNX14,RAB11A,RAB2A,MSX1,CACNB3,RAF1,ARMCX3,ROCK2,IL10,DDRGK1,APPBP2,ADIPOQ,EXOC5,EXOC8,TBC1D5,BRD3,LMAN1,RAB9B,WDR83OS,TBC1D17,LGI1,CTTN,TRIM23,STRADB,ASIC2,SPCS1,SH3GLB1,NETO2,HSP90B1,ATG3,PLEKHA8,PSMD10,TIMM23,VAMP2,ATAD1,PEX3,RPF2,TBC1D13,SPRN,EMC10,FAM149B1,MIA2,MIR130B,CLIP3,SNAP29,LMNB1,ERRFI1,TMED1,AKT2,VPS26B,CETN2,CHMP1A,BAX,RTP4,TRAF3IP2,EFCAB7,TOM1L1,ID4,LAMP2,AHCYL1,ARL11,ZDHHC14,KPNA1,DDX1,MACIR,RAB23,IMMP2L,LRRTM1,GPM6B,BBS5,ACVR1C,G3BP2,DNAJC27,TIMM17A,TNIK,PPP1R10,HM13,EHD4,AQP11,DNAJB6,SFN,ZBTB16,MCL1,ATG7,KCNIP3,FAM53C,TP53INP2,SCAMP2,OPTN,VPS18,CHMP2B,PIGW,PEX5L,SAR1B,TXNIP,EDNRA,SMYD3,XPOT,PAX6,VPS39,TSPAN10,FKRP,TMED4,AKT1,AIFM1,ARFGAP1,PPP3CA,WNT7A,KICS2,TNFAIP3,RAB3D,NUDCD3,TXN,SNX18,CALR,NSG1,NFKBIA,ROMO1,ENY2,SYNRG,LHFPL4,LMBRD1,PAK2,FHIP1B,XBP1,CYB5R4,TSPAN5,BUB3,TOLLIP,CPE,SYVN1,PRKCE,TMEM88,NRP1,PIP5K1A,TSG101,STX18,THY1,INSIG2,PARP11,HIKESHI,UTP25,WRAP53,OLFM2,LAMTOR3,ZFAND2B,PHAX,ROCK1,STX10,SURF4,GPIHBP1,NEO1,STAU1,NLGN1,NUP107,RAB22A,PAFAH1B1,CACNB2,TIAM1,ARFGAP3,GORASP2,BICD2,BET1L,TIMM21,STX17,CPLX1,MIR301B,YWHAZ,MTX2,WDR19,CCDC47,PIK3R1,RAN,AGK,NR0B1,SRP72,PIK3R2,LAMTOR2,PRRT1,SNX24,CTSA,AP2S1,EMC8,SEC62,STK11,STX11,TMED9,STX16,SELENOT,LIN7B,TESC,HDAC6,ZDHHC17,SGF29,SCG5,DERL2,RAB14,ARFGEF1,SYK,LAMP3,YKT6,RAB33B,TIMM13,LACRT,VMP1,NUP37,XPO1,SCN3B,ODR4,SPTBN1,UBAP1,RNF26,XRCC5,VIP,NPTX1,YIPF5,VAMP3,PICK1,TRMT10B,VPS54,RAB5A,GLRB,USE1,SNAP23,STX6,TIMM8B,DRD1,ARL6,ARL2BP,EHD3,EXOC2,NUP62,CBLN4,WBP2,TRAM1L1,NHERF1,C1QL2,STK3,UNC119B,ATP6V1D,STX8,SCG2,YWHAH,ID1,RAB9A,RAB18,NXT1,HNF1B,CDC42,GOSR2,CSNK1E,FERMT2,ARFIP1,DDX42,RAB4A,ABCB9,UBAC2,ZDHHC15,KCNB1,FCHSD2,TULP3,CD81,CCDC186,MDC1,IFT22,HSPA5,SEPTIN7,COG1,VTI1B,AP2M1,RUVBL2,MAVS,PPY,TVP23B,MCM8,ISG15,RAB1B,VAMP8,DHX9,RABL3,NAPG,GAS8,CMTM6,TOMM22,RAB3B,HYCC1,JAGN1,EMC4,FBLN5,RAB29,LRWD1,NEDD8,ZFAND2A,LCA5,EMC1,RAB13,DLG3,DLG1,RAB3A,BECN1,TOPORS,FIS1,NAPA,CBLN1,POLA2,BAG3,SOX9,CBL,VTA1,WDR11,VIPAS39,RABL2B,SYNGR1,JAKMIP1,RAB28,HGS,SLMAP,PRPF19,OS9,COPZ2,CSE1L,NUP42,ARF4,DLG4,CER1,HOMER1,RPAIN,TMEM147,TMED7,TOR1B,LARGE1,SNX20,SLC15A1,HSPA8,ARHGAP1,TRAM1,SSR2,EHD1,SSR1,KIF3B,SYNJ2BP,STK4,TP53,SPCS3,SDCBP,MDM2,BET1,SGTA,SCFD1,CHMP4C,SLC15A2,MAPRE1,CHMP5,HOMER3,SUFU,MLC1,CD3G,IPO8,GPHN,FAF1,CDAN1,RAB3C,SNX2,SAMM50,KPNA2,SNX22,CHRDL1,SSR3,HINFP,RAB11B,BCL6,ARL4D,CTDSPL2,TOPBP1,CDK5,GOLPH3L,SEC22A,FGF7,RANGRF,ERLEC1,RPA2,ING1,SEC13,TESPA1,RANBP6,PPT1,ACTB,TNF,GRPEL2,ARF6,H1-5,EXOC3,RP2,SEC61A1,GJA1,YWHAB,GPR89A,RB1,NUP35,IK,TMEM107,RAB31,TMSB4X,MDFI,CDKN1A,RAB37,TOMM20 |
| 1.256e-17 | -38.92 | APP (amyloid beta precursor protein) | protein interactions | 351 | 2342 | 834 | 19454 | 5460 |
OARD1,DIRAS1,NCSTN,H2BC1,PLS3,MOB3C,SMARCB1,ABCF1,CDK5,RAB5C,IFI16,SPATA2,DDRGK1,SPON1,CTNNB1,YWHAG,GSTO1,DDX1,PSME2,MITF,RAB1B,ECHDC1,HNRNPL,CCT7,ANKRA2,BET1,FGF16,USP6NL,LAP3,SYK,TOM1L2,SRARP,PACRG,PDSS2,GOSR1,NDUFS2,CYB561D2,CREBBP,OSM,BTF3,PELI3,KIAA1191,H1-1,PHF7,RPS26,SURF2,MTG1,LMBR1L,PAPSS2,IRF2,CHAC2,TAGLN2,PPP1R3C,ZNF581,AGER,GUCD1,RP9,CERK,SGIP1,PSME1,YIF1A,NETO1,TGFBR2,ENY2,ZNF473,TNFRSF14,NOL12,KIAA0513,RAP1B,PHYH,GNRH2,SLC38A2,LCP2,LMAN1,MND1,FGFR1,PML,MAPKAPK3,MAIP1,SMG5,DERL1,RNF34,FTSJ1,BCL2A1,UGP2,ATF4,TMEM41A,GORASP2,CFL1,STN1,GEMIN8,CHRAC1,EXOSC1,TMA7,UQCRC2,INTS12,CDC20,CSNK1E,RAF1,IL7,NDUFS6,SLCO2B1,BCKDK,MAP3K11,HSPD1,GAL3ST1,DHX16,FLOT1,IFIH1,ACTL6B,PDAP1,TMEM30A,HYPK,AFAP1L2,DNAJB9,PPIA,SUPT4H1,CDKN1A,SLC48A1,ARMCX3,FOXS1,USP39,CRYAB,PRSS23,TCF19,ATPAF2,CFDP1,HSCB,ATP6V1G1,RNF11,CSRP1,ACO2,HBEGF,TMEM183A,OCEL1,PPP1R17,HSP90AA1,RAB28,POLR2F,SEC61B,ACTB,TRIM46,PRDX2,TP53TG5,ERH,USP5,MAT2B,NDUFA2,PGM1,APOBEC3H,NDUFS3,LLPH,OR4D6,DHRS7B,VAC14,DNAJC30,FRMD8,CDK2AP2,TRIM63,ZSCAN5A,TSSC4,ABHD10,ADD2,PAGR1,APBB3,VTA1,KLHL32,MOV10,PRICKLE2,PDE1A,MSMB,UBXN10,CLP1,SPMIP9,RPL12,SMAD3,TES,DECR2,TCEAL8,PLEKHF2,MRPL24,RABL3,PCK2,CDK7,GABARAPL2,UQCRC1,MED30,FITM1,MEST,LIMS2,RPL26L1,ZKSCAN1,DCTN6,RHOU,TCEA1,HMCES,PIK3R2,SLC7A1,CDC42EP4,TMUB1,CIAO1,SKAP2,DNAJC8,HMOX2,ARFGAP3,COL1A2,MAPRE1,POP7,METAP2,GXYLT1,RPS12,ALB,COA5,NDP,SERTM1,FERMT2,UBB,CBLN4,FBXL7,TPPP,GNAZ,CCT8,ACTR1B,ICAM3,KRAS,PAEP,PAX6,RIOX2,CIAO3,SIVA1,RIMS4,TGFB2,SRSF1,HOMER3,TRIR,TMEM97,TANK,GOSR2,GPR15,COX6A2,FOS,PYM1,MROH8,APPBP2,RER1,TNNT2,CATIP,BRMS1,CASP4,THAP7,ZNF343,NFKBIB,APEX2,TRIM44,SNRNP40,DTD2,PPP5C,IREB2,UBL4A,ZNHIT1,ZMYM3,GLRX5,NECAP1,IL20RB,UGCG,TCEA2,RAB13,FGF12,CAMKV,H2BC14,XAF1,PGAM1,TCEANC2,ORMDL3,COPS5,LANCL2,KCNJ10,ARMC1,COMT,EEF1B2,ARL4D,TRAPPC3,NUDT9,RGS1,RPS16,IFRD2,RBM42,PPP1R8,FGF13,SETD3,MRPL10,TRAM1,USE1,TCP11L1,RPA2,ZNF770,NAPG,TSPAN5,EIF4E,OLFM3,MORF4L1,C9orf72,PCBD1,LACRT,MARCHF3,ATRAID,LIG3,HS3ST1,FKBPL,ING2,GABPA,MKKS,CCR2,SRC,DTWD1,SRPK2,SMURF1,SNCB,FAM200A,GTF2E2,NLRP2,GTPBP1,RBPJ,ARGLU1,PPAN,PLSCR1,AKT2,SRSF8,BLOC1S2,EMC8,HS2ST1,SERPIND1,RAB3D,IDO1,FIG4,TRAF6,CD58,RPL23,SP2,IGBP1,BUD31,PRKAB1,ATP5PO,PPARG,RTKN,COMMD2,NUP50,GPC1,IL1B,COIL,GRB10,NOP16,TTC23,TOMM40,SOCS5,PLEKHJ1,NTRK3,UBE2S,ELK3,RGS5,LRRC1,CDC7,CLDN3,TMCC1,MRPL11,TBK1,SMAD1,CLEC2B,NECAP2,SOCS3,PLAAT5,MRPL49,TFPT,WASL,TOM1,TCP11L2,CACNG3,CALR,MPG,CRADD,GTF2E1,NOVA1,CRBN,PDYN,RCHY1,CDCA3,RGS10,EIF2B2,POLE3,ATP5PD,RPS14,MX1,TMEM106A,SNAI2,ZNF574,OXSR1,RPLP0,PRPF4,ORMDL1,NXPE3,TMEM126B,FLCN,SYVN1,DGCR8,POLDIP2,FLRT3,PYCR2,AAMDC,HYCC2,PPP1CC,ATOSB,PIP4K2C,PNPO,STK11,NAPA,EPHA2,GIMAP4,GUCY1B1,STUB1,VAMP3,OPTN,CHCHD6,CFAP298,UBE2I,RPS20,WDR45,SLC25A4,RAB14,ZNF622,KLK9,ETFB,ODAM,SPC24,TRMT1L,DNAJC25,COX4I2,NIM1K,HGS,RPL31,TFPI,PSMA1,PAK6,RAB8B,UTP25,DCTPP1,TBC1D10C,QPCTL,CPEB1,DENND6B,FUBP3,GSTA1,GYS1,RAB35,TERB2,ACHE,RPS10,CDK17,ZNF740,NOB1,UBL3,GLRB,TIRAP,SEC62,ACAA2,TIMP3,JAGN1,LYPLA2,CHRNA7,HIGD2A,MYC,DRAP1,ZMAT3,FBXW11,H2AZ2,CIRBP,CDKL2,YAE1,VDAC2,REG1A,GTDC1,GPN2,SSH3,APEX1,ESR2,GADD45G,GTPBP8,EXOC3,DDX42,SLC25A24,SH3GLB1,MRPL52,GALNT12,ZNF365,PSMA5,STX11,SMIM11,PCYT1B,MSTN,USP2,DPP4,GAPDH,TRAPPC2L,SHC1,TAF9,IER3,ITGA6,ACSL4,MRPS9,SNAP25,MXI1,RASGRP2,AGO1,HIKESHI,KLF4,RAG1,DYRK2,PSEN2,ITM2B,STOML3,CLU,AKT1,CARS1,GPRASP3,ARL6IP6,IL15,GLOD4,CCSER2,CDIPT,SF3B6,PPP2R5E,MACROH2A1,RCBTB1,IFI6,CTSB,DYRK1A,IDE,ARFGAP1,MAPK10,JUN,PPID,EXOSC3,SKA3,RPN1,RPS11,SLC17A5,OPA3,HINT2,ENKD1,RPS27A,CFC1,PDIA3,HMGA1,HNRNPA1,DLK2,BCL7C,PSMB4,SNX17,PLEKHO2,MAP1LC3A,BEND5,RASL12,ERVFRD-1,STXBP1,ATAT1,RGL1,KLF3,ARCN1,FKBP1A,EMG1,C1D,MED11,CMAS,CCND3,NFYA,SLC41A3,YWHAZ,FYTTD1,HTRA2,PAXX,AVPI1,RPS9,LGALS3,TUBB,TAF11,FCF1,GPAM,MAP2K3,MAGEA4,TNFAIP8L1,CAMK1,SOD2,PQBP1,IGF1R,FN3KRP,CNOT7,RNF115,PSEN1,FAM133B,KIAA1143,POR,NME2,RAB3A,BRD3,TRAPPC4,DNAJC4,EIF4E2,CXCL14,CHID1,NAT2,CWC15,TMCC2,MDM2,TIMMDC1,PIP5K1A,KLF12,KDELR2,ZCCHC17,DRAM1,SHOC2,AGAP1,MET,HELLS,GPR78,SLC22A6,PDHB,MRPL20,UTP23,DNAJC19,PAIP2,CCHCR1,CTNNA1,MRPL53,CINP,MGST3,VIRMA,MED9,TOP3B,KCTD16,SERPINA3,CAAP1,RPAP3,RUVBL2,VDAC1,GJB1,ARHGAP15,POGK,UBE2E2,SYNJ2BP,SHC3,AGR2,ANKRD50,YWHAB,SPINT2,FAAP100,RFX5,NRSN1,S100A8,ELK1,DIO3,SIGMAR1,PAK2,MRPS18A,MXD1,NMRK1,KLC2,STK26,AKAP1,MRPL34,HSPA8,STAU1,RNF41,TRIM52,CDKN2D,CHTOP,FGFBP2,GCC1,ARMC7,DNAJB6,EFHD2,TACO1,DYNLRB2,PSMD4,CDK4,HADH,NEFL,RBM34,IK,TAB2,BACE1,NAE1,RAB27A,IMP4,RBCK1,KPNA2,RASL10B,CCIN,HCFC1R1,EDEM1,RIT2,TMA16,CSNK2A1,NOS1AP,SNRNP70,NXT2,TUBG1,RPL10A,TMOD2,COX4I1,SYNCRIP,SLAIN2,ZSCAN1,SMYD3,PARD6A,KCNAB1,UBE2M,E2F6,ORC6,ZNF322,HSPA5,SUB1,RPF2,LSM6,PKNOX1,EIF3G,SLC1A1,EIF2S2,ADRM1,DUSP3,PPP1R10,ACO1,FEN1,SSBP3,CYB5B,EIF1AX,CDK5R1,TMT1A,NDUFA4,UBE3A,RASGRP3,G3BP1,RRAGB,ANP32B,RETREG1,STOML2,HMBS,UBXN6,NKIRAS1,ATG7,RASSF8,AHSA1,CIART,OCIAD2,FAM3A,DNM2,SASH3,GATD3,RPLP1,HP1BP3,SNX1,KIF3B,COPS7B,RAB11B,NTMT1,CPLX2,NDUFA5,PSRC1,BET1L,TRUB1,NSFL1C,SPATA4,PSMC1,POLA2,CUL3,DSN1,NDUFB6,GALE,SAMHD1,RIOK2,BLOC1S5,MOBP,MAGEH1,BOLA1,APOBEC3G,ZNF22,ARPP19,RPL37A,MAD2L1,YTHDF2,GGCT,THAP1,MLLT6,MAP1LC3B,HINT3,HSPA13,OTX2,HSD17B10,TMX3,RING1,POLL,CTNND1,DUSP21,CD36,BMPR1B,MAP2K6,TOP1,MAPRE2,EIF2B5,KCNMB2,ARF6,CAV1,TPT1,ACBD6,ATG16L1,TPRA1,MTRES1,NOL7,FADS2,SIRT7,LRRC8D,ITGA2,CCDC106,CTSD,RETSAT,TUFM,ZCCHC12,ATP5F1A,OR2W1,HOXC4,TMEM255A,DEDD,CDPF1,SULT1A3,PLP1,GAS2 |
| 1.276e-17 | -38.90 | RACK1 (receptor for activated C kinase 1) | protein interactions | 10399 | 658 | 285 | 19454 | 5460 |
MAP2K1,NUFIP2,PIH1D1,RPL27A,SYK,PAFAH1B1,FXR2,UFL1,ADRB2,SSR3,STAU1,RPS28,HSPA8,EP300,ARRDC3,H1-10,FTSJ3,COP1,CRMP1,RPS26,MYC,SFN,BTF3,USP16,STAT1,SNRNP40,PPP5C,RPL10,ADH1B,SMU1,LRP12,MCPH1,PIR,NIM1K,SEC61G,RPL18,RPS23,TRMT1L,ISG15,TRAF2,SOX2,RPS7,EEF2,KRAS,RPL28,RPS4X,PAK6,RPL31,PABPC1,AK2,AGR2,DRG1,CNOT2,IFI16,RPL6,WWP2,CPEB1,DDRGK1,CTNNB1,RPS10,EIF2S1,NOB1,ISG20L2,LYAR,EED,WDR82,RPA2,UBE2M,KCNAB1,PRKCA,DYRK2,HECTD1,CFTR,RPS15,ZC3H15,EIF4E,MARS1,BAP1,RPL27,NLE1,HNRNPH2,LSM12,DERL1,EIF3G,SPOP,TRIM23,RC3H2,PDCD4,UBE2H,GABRB3,PTPN11,RPL7A,PRKCE,SMURF1,SRC,SRPK2,RPS3,PSPC1,EIF2S2,SEC61A1,NHERF1,DNAJC2,IK,GRAP2,NUPR1,RNF8,UBL4A,INSIG2,TNRC6C,TP53,MRPL47,RPSA,ESS2,H3C1,MEPCE,RPL17,EIF1AD,POC1B,ABCE1,RPL3,DHX9,TUBG1,RPL24,SNRNP70,BECN1,RPS2,RPL10A,ENY2,CSNK2A1,CD81,COPS5,GNG2,ELOC,FZR1,CAND1,RPS16,RPS27L,RBM42,SYNCRIP,TRIM45,LARP4B,EMC9,AGTRAP,CDKN1A,DET1,PTN,GPC1,CMAS,G3BP2,SAT1,DCAF4,BRCA1,RPS5,RIT1,ACO2,NOP16,CUL2,CUL3,RFC5,PRPF31,DYNLL1,RPL35,TUBB,RBBP4,GNB1,PRRC2A,RPL19,FAU,EIF3K,CDC7,RPL37A,RPS9,SEC61B,RPN1,EZH2,PPID,EXOSC3,NGB,RPS11,ITGB5,B3GNT2,RAF1,E2F4,PPP2R1A,JUN,G3BP1,RBBP7,TRIM26,TRIM37,GNL1,SAR1B,EIF2D,TRIP4,PPAN,ZC3H7A,JAK1,RPS24,TRAF6,RSBN1L,DCAF11,AHSA1,HNRNPD,PIK3R1,ATG7,HNRNPA1,FEM1B,CISH,RPL7,RPL9,RPL8,PHB1,RPLP2,RPLP1,METTL14,HSP90B1,GRM2,TP53INP2,RPL26L1,RPLP0,NOL7,RPS14,ATG16L1,WDR83,TPT1,ST7,EIF3J,FBXW7,RPL4,BRIX1,RPA3,PNO1,SIRT7,PRKCB,SYVN1,MAVS,MTDH,ASCC1,TXNIP,PPTC7,IL2RB,FBXO7,IFNAR1,AR,PPP1CC,ZNF622,NDN,RPL13A,RPL22,PELP1,CCNF,METAP2,POP7,CAB39,RPS12,RPS20,DAP,ILF2,SRP72,APEH,RNF181,FBP1,MAP2K3,EEF1A1,RPL15,HUWE1,RPS13,OLA1,ARF4,RIGI,EIF3E,MDC1,NKRF,RPL23A,IGF1R,SLC6A3,STYK1,HDAC6,EIF2B2,CDK9,RPL12,EIF4E2,MAP2K6,ARL10,LDLR,RB1 |
| 1.514e-17 | -38.73 | CTNNB1 (catenin beta 1) | protein interactions | 1499 | 926 | 377 | 19454 | 5460 |
TRIM63,FARSA,HUWE1,PSEN1,EGR1,PPP1R12A,FAF1,IGF1R,RPL23A,MAP2K3,RPL35A,CDK9,CITED1,HRAS,PTPN1,SMAD3,RPL12,TES,TNKS,FOXP1,MOV10,SUV39H1,FBXW7,NF2,DAD1,GID8,DVL2,RHOU,RTN4,MET,RARS1,NFYB,CCNA2,UQCRC1,RHOJ,COPE,TMOD3,VIRMA,FERMT2,CTNNA1,CCNF,MSN,NEURL2,MAPRE1,CDC73,LRP6,SMAD2,CTNNBIP1,FLOT1,SSRP1,FANCG,RPS27A,MAEA,HNRNPA2B1,SLC25A5,NUDT5,HSPD1,PCNA,CTNNA2,PARP11,RPS11,NAA15,RAF1,ACTN4,PPP2R1A,EGLN3,PPIA,RPL9,RPL8,RPLP2,RB1CC1,VCPIP1,PPP2R5A,PDIA3,PIK3R1,HNRNPA1,UCHL3,JADE1,TXNL1,USP39,CRYAB,SLC25A3,IRF2BPL,ACTL6A,LGALS3,SIAH1,ACTB,TUBB,UBTD1,SNRPD1,SNRPD2,YWHAZ,RHOB,DCAF4,BRCA1,ILK,RPS5,HSP90AA1,RAB11A,PKP4,NFYA,AUH,ACO2,HNRNPK,TGFBR2,PSMA5,AKAP12,H3C1,DHX9,CAPZA2,PIK3CA,CBX3,RPSA,KBTBD4,FZR1,CAND1,KLK3,UBE2N,RAC2,CDK6,USP2,TPM3,GAPDH,API5,BCL6,PSEN2,PML,BAP1,PGK1,LSM12,FGFR1,CDC42,CSNK2B,IGF2BP1,RPL7A,SMARCA5,SLC25A1,AKT1,DNAJC5,CFL1,ARHGAP21,RUVBL1,USP30,RAB8B,COX7B,RPS4X,RPL31,BCL9,TRIM21,EWSR1,MYO1B,TUBB4B,MOB3C,EEF2,TUBA1A,MITF,RPS10,HSP90AB1,RAB35,ARHGAP5,ARMC8,POU5F1,DDX1,CBL,WWP2,CNOT2,XPO1,DKK1,PHB2,SPECC1L,RPS28,BMPR1A,DDX39B,DDX5,CSNK1A1,USP6NL,SEC62,TAX1BP1,STAT1,PTPRZ1,MATR3,ESR2,RPL10,CBX5,PSMB6,LMBR1L,VDAC2,FBXW11,CCT2,HNRNPC,LDHB,SFN,MYC,CREBBP,PSMD1,BTF3,THRAP3,HSPE1,EIF3E,SOCS2,CTNND1,DLG1,HINT1,SNAP23,ZC3H11A,UBE2B,JOSD1,MAP1LC3B,TOP1,ZBTB2,CAV1,PSMD7,CRBN,TLE1,NFKB1,RNF14,CDH11,HDAC6,HMGB1,RPL4,PNO1,SQSTM1,HSP90B1,LMNA,JUP,CDK1,IFRD1,RPLP0,MYL12B,CCND1,RPS14,EIF3J,SIPA1L1,CD47,MAGOHB,TXN,EIF4A3,STUB1,CFAP298,RPS20,PTEN,GSK3A,GANAB,TADA3,EPHA2,SEC13,NONO,AR,RUNX1,ATP5F1A,TRIM37,G3BP1,TRIM26,COX8A,RPS24,UBE3A,EZH2,CDK5R1,MARCKSL1,GFPT1,SPTAN1,CACYBP,ERLIN1,CBFB,GJA1,TRAF6,RHOG,UBE2D1,RPL23,BCL2L1,RASSF8,PRPF19,NSFL1C,GPC1,PTN,SKP1,WBP2,ADNP,PPARG,MYL6,RND2,PPP1CB,IDH3B,UBE2S,ARF1,AP2M1,LMNB1,FAS,SP1,FHIT,NTRK3,GRB10,CUL3,VEZT,HNF1B,USP13,OTUD7B,TOLLIP,CAPZA1,ZBTB25,SLC25A11,ABCE1,RPL3,NHERF1,CDH8,PSMC3,RNF8,SAPCD1,EGR2,RPS16,TMPO,COX4I1,SYNCRIP,RNF128,SMAD4,USP15,RPL10A,RPS2,RBM17,CSNK2A1,COPS5,CRYL1,HSPA5,EIF4E,ZNF326,RPA2,HECTD1,PRKCA,CFTR,NEK2,SRC,SMURF1,LIG3,ZBTB33,CREB1,RPS3,TSSK1B,PSMC5,ATP1A1,SUB1,PTPN11,TNFAIP3,RPS17,SATB1,KRAS,POLDIP3,RPL28,PABPC1,RUVBL2,PICK1,KCTD11,RPL18,MTA2,RND3,RANBP1,ARFGEF1,MED9,ISG15,SOX2,TCP1,EIF2S1,MTERF2,ELK1,FBXO31,FKBP4,IKBKB,HSPB1,TAX1BP3,STAU1,XRCC5,EP300,HSPA8,CTBP1,KLC2,PSMD4,ATP5F1B,CDH7 |
| 1.618e-17 | -38.66 | cellular macromolecule localization | biological process | GO:0070727 | 1962 | 743 | 18204 | 5365 |
NUP37,VMP1,LACRT,TIMM13,RAB33B,YKT6,LAMP3,UBAP1,SPTBN1,ODR4,SCN3B,XPO1,SGF29,ZDHHC17,HDAC6,TESC,LIN7B,SELENOT,STX16,STX11,TMED9,STK11,SYK,ARFGEF1,RAB14,DERL2,SCG5,DRD1,TIMM8B,NHERF1,TRAM1L1,WBP2,CBLN4,NUP62,EXOC2,EHD3,ARL6,ARL2BP,VPS54,TRMT10B,PICK1,VAMP3,YIPF5,NPTX1,VIP,XRCC5,RNF26,STX6,SNAP23,USE1,GLRB,RAB5A,STAU1,NEO1,GPIHBP1,SURF4,STX10,ROCK1,PHAX,ZFAND2B,ARFGAP3,TIAM1,CACNB2,PAFAH1B1,NUP107,RAB22A,NLGN1,UTP25,HIKESHI,PARP11,INSIG2,THY1,STX18,LAMTOR3,OLFM2,WRAP53,CTSA,PRRT1,SNX24,LAMTOR2,SEC62,EMC8,AP2S1,STX17,TIMM21,BET1L,BICD2,GORASP2,PIK3R2,SRP72,AGK,NR0B1,PIK3R1,RAN,WDR19,CCDC47,MTX2,YWHAZ,MIR301B,CPLX1,TXN,NUDCD3,RAB3D,TNFAIP3,KICS2,ENY2,ROMO1,NFKBIA,NSG1,CALR,SNX18,FUBP3,TMED4,FKRP,TSPAN10,VPS39,PPP3CA,WNT7A,ARFGAP1,AKT1,AIFM1,TMEM88,PRKCE,SYVN1,TSG101,PIP5K1A,NRP1,PAK2,LMBRD1,SYNRG,LHFPL4,CPE,TOLLIP,BUB3,TSPAN5,CYB5R4,XBP1,FHIP1B,AHCYL1,LAMP2,ID4,TOM1L1,EFCAB7,RTP4,TRAF3IP2,BAX,CHMP1A,CETN2,DNAJC27,ACVR1C,G3BP2,BBS5,GPM6B,LRRTM1,IMMP2L,RAB23,MACIR,DDX1,KPNA1,ARL11,ZDHHC14,LMNB1,SNAP29,CLIP3,MIR130B,MIA2,FAM149B1,EMC10,VPS26B,AKT2,TMED1,ERRFI1,PIGW,CHMP2B,VPS18,OPTN,SCAMP2,TP53INP2,PAX6,XPOT,SMYD3,EDNRA,TXNIP,PEX5L,SAR1B,DNAJB6,SFN,EHD4,AQP11,HM13,PPP1R10,TNIK,TIMM17A,FAM53C,KCNIP3,ATG7,MCL1,ZBTB16,TESPA1,SEC13,ING1,RPA2,ERLEC1,GRPEL2,TNF,ACTB,PPT1,RANBP6,HINFP,SSR3,CHRDL1,SNX22,RANGRF,SEC22A,FGF7,GOLPH3L,CDK5,TOPBP1,CTDSPL2,RAB11B,BCL6,ARL4D,RAB31,TMEM107,IK,NUP35,RB1,GPR89A,TOMM20,RAB37,CDKN1A,MDFI,TMSB4X,H1-5,ARF6,CASC3,YWHAB,SEC61A1,GJA1,RP2,EXOC3,SYNJ2BP,KIF3B,EHD1,SSR1,SSR2,MDM2,SDCBP,SPCS3,TP53,STK4,TMED7,TOR1B,TMEM147,RPAIN,HOMER1,DLG4,CER1,ARF4,NUP42,ARHGAP1,TRAM1,HSPA8,SLC15A1,SNX20,LARGE1,FAF1,GPHN,IPO8,KPNA2,SAMM50,SNX2,RAB3C,CDAN1,SLC15A2,CHMP4C,SCFD1,SGTA,BET1,CD3G,MLC1,HOMER3,SUFU,CHMP5,MAPRE1,RAB29,FBLN5,EMC4,JAGN1,HYCC1,LCA5,ZFAND2A,NEDD8,LRWD1,ISG15,MCM8,PPY,TVP23B,RAB3B,TOMM22,CMTM6,GAS8,NAPG,RABL3,DHX9,RAB1B,VAMP8,HGS,RAB28,JAKMIP1,SYNGR1,RABL2B,VIPAS39,WDR11,CSE1L,COPZ2,OS9,PRPF19,SLMAP,POLA2,CBLN1,NAPA,FIS1,BECN1,TOPORS,RAB3A,DLG1,DLG3,RAB13,EMC1,VTA1,CBL,SOX9,BAG3,ARFIP1,FERMT2,GOSR2,CSNK1E,CDC42,FCHSD2,KCNB1,ZDHHC15,UBAC2,ABCB9,RAB4A,DDX42,STX8,ATP6V1D,UNC119B,STK3,C1QL2,HNF1B,NXT1,RAB18,RAB9A,YWHAH,ID1,SCG2,RUVBL2,AP2M1,COG1,VTI1B,SEPTIN7,MAVS,CCDC186,CD81,TULP3,HSPA5,IFT22,MDC1,RAP1A,RILPL2,ESAM,SRP14,TFRC,NXT2,CLTRN,SEC63,SARM1,ATG16L1,ATG4A,CD63,GPAA1,PHYHIP,FCHO2,GRPEL1,TMIGD1,ZDHHC4,RINT1,CLU,UBL4A,MACROH2A2,TERT,KCNJ8,LAMP5,SSNA1,FGF13,IGSF11,DISC1,SRPRA,PML,NECAP1,CUTA,PACRG,RAB35,RAB19,LAMTOR1,CD2AP,NDP,DNLZ,VPS16,NLGN2,ARL4A,RAB8B,CHAMP1,TOM1,STX5,SEC23A,SNX10,ZMAT3,PHB2,SQSTM1,LEP,RAB40AL,TM9SF4,SRGN,MGARP,C1QL3,ANGPT1,PPID,SH3BP4,DAG1,CDK20,TOMM6,SEC61A2,KDELR1,SYS1,SNX17,FBXO7,MAIP1,MECP2,EMC9,GOLGA7,TOMM7,AP3S2,SCG3,TMED3,NBN,SNX11,SNX1,EHBP1,SNCG,TRIM3,KDELR2,SLC1A1,VPS26C,CTNNB1,RALA,IFT25,AP1M1,RAB5C,SNX5,CAMK2G,VPS26A,RNF128,UNC50,GABARAP,PDIA2,SELENOS,ASB3,FAM53B,PEX26,LMNA,NOP53,SPTSSA,KPNA6,FAM91A1,TOMM40L,DVL2,RAMP3,TUBA1A,RAB27A,DERL1,BCAP29,SLC4A8,STXBP1,MCPH1,LRP6,TSPAN15,VLDLR,STX7,TOR1AIP2,SKP1,ARRDC3,NUP50,TM9SF1,NUP153,ATG4C,RIC3,SNX12,CCHCR1,SEC61B,H2AC4,TIMM8A,SEC22C,ERP29,CAMLG,YWHAG,MYO6,MX2,LRRC4,COPE,DPP10,DUOXA2,FLOT1,SNAP91,VPS33A,TNPO2,AP1G2,ROPN1B,AP1S2,HSPD1,CPLX3,CD36,SNAPIN,SIN3A,CHMP2A,RRAGB,TIMM29,MLH3,CACNG3,SFT2D2,SMURF1,ILDR1,EMP2,RTN4,DNM2,SEPTIN6,TIA1,TSPAN17,GUK1,JAK1,EXOC1,MSX1,RAB2A,RAB11A,SNX14,VAMP7,RAB6B,CNTNAP1,APPBP2,ADIPOQ,DDRGK1,IL10,ROCK2,ARMCX3,RAF1,CACNB3,TRIM46,S100A10,PLEKHF1,RHOB,AGER,ABHD17A,MAPRE2,CORO1C,STX1A,RAB6A,EPHA2,VPS28,EMC6,SPCS1,ASIC2,STRADB,TRIM23,CTTN,LGI1,SPRN,TBC1D13,RPF2,ATAD1,PEX3,VAMP2,TIMM23,PLEKHA8,PSMD10,ATG3,HSP90B1,NETO2,SH3GLB1,EXOC8,EXOC5,TBC1D17,WDR83OS,RAB9B,LMAN1,BRD3,TBC1D5,VPS4A,RRAGA,GNPTG,SRPRB,FKBP8,TMEM30A,MADCAM1,ERCC3,ARF1,BCS1L,SVBP,TOMM70,NETO1,DDIT3,AZGP1,COMT,P2RY1,SCAMP5,ADORA1,RRP7A,CHMP1B,CEP41,EZH2,OSBPL8,RAB32,SRP54,TPBG,RAD21,CNTN2,TRAK2,AP1AR,AGAP1,IKBKB,CHCHD4,ARCN1,PPARG,LIN7C,DESI1,ANKRD50,YIF1A,PAQR3,RAB39B,RPL23,CCDC22,RABIF,F11R,SPCS2,GLE1,GABARAPL2,TMED5,UFD1,TSPO,RAP2A,GOLGA7B,PGR,STX12,JUP,CETN3,SEC22B,FGF10,EMC2,CHP1,TIMM10,SNX33,VPS4B,AP5S1,ZDHHC24,TOM1L2,TMEM115,TRIM37,PEX13,EIF2D,CHGA,AFTPH,PRKCB,SUMO1,RER1,H2BC11,EDEM1,TTC8,HPS6,MACROH2A1,RIT2,XPO5,ACTN4,ATP1B1,HYCC2,AIP,ARL5B,AP5M1,CTNNA1,FRMD8,TMSB10,ATP1B3,TOMM40,ZFAND6,GOSR1,HSPB1,FAF2,SLU7,DNAJC19,CASK,PREPL,PMPCA,SEC61G,HSP90AA1,BTF3,SYNDIG1,SNAP25,CNIH4,MTCH2,WDR45,GDI2,REP15,MARCHF5,CDK1,HTR2A,INPP5K,TAX1BP1,RAB1A,AGAP2,FKBP1B,BLOC1S3,CAV3,SUPT7L,PLEKHF2,CAV1,MCOLN1,NECAP2,TNKS,VAMP5,ATG9A,ARL6IP5,EGR2,MTM1,TNKS2,PSEN1,PTN,AP2A1,CD4,TNPO3,CRB3,SMAD2,TRAM2,SNX3 |
| 1.720e-17 | -38.60 | nitrogen compound transport | biological process | GO:0071705 | 1507 | 591 | 18204 | 5365 |
SEC22B,RAB29,GJB1,JAGN1,SLC6A3,LCA5,CD209,SLC7A14,OSBP,CHP1,TIMM10,FOLR2,SNX33,VPS4B,THOC3,AP5S1,SRSF7,TOM1L2,PPY,TVP23B,RAB3B,TMEM115,TOMM22,SLC7A8,SLC5A6,CMTM6,TRIM37,NAPG,PEX13,RABL3,EIF2D,DHX9,RAB1B,VAMP8,HGS,SLC19A3,RAB28,AFTPH,PRKCB,JAKMIP1,SLC25A24,RABL2B,VIPAS39,CRHR1,WDR11,CSE1L,TTC8,HPS6,COPZ2,SLC38A9,OS9,XPO5,ACTN4,SLC35A5,POLA2,CBLN1,LRRC8C,NAPA,ATP1B1,HBB,TST,BECN1,RAB3A,RAB13,GHRL,VTA1,CBL,AP5M1,ARL5B,BAG3,ARFIP1,RTRAF,GOSR2,TOMM40,SLC6A2,ZFAND6,GOSR1,SLC35A1,HSPB1,FAF2,SLU7,FCHSD2,PEG10,SLC43A2,DNAJC19,ABCB9,PREPL,HNRNPA1,RAB4A,SEC61G,THOC2,BTF3,STX8,HSP90AA1,SFXN2,UNC119B,SYNDIG1,CHRM5,CSF2,STK3,SNAP25,CNIH4,MTCH2,GDI2,SLC48A1,HNF1B,NXT1,REP15,RAB18,RAB9A,YWHAH,SLC6A7,SCG2,RAB1A,AGAP2,FKBP1B,BLOC1S3,AP2M1,PLEKHF2,COG1,SLC25A17,VTI1B,CAV1,CPTP,MCOLN1,NECAP2,TNKS,SMG5,SLC6A8,VAMP5,CCDC186,AQP3,MTM1,ARL6IP5,EGR2,PSEN1,AP2A1,SLC25A51,SLC19A2,TNPO3,HSPA5,IFT22,ALKBH5,SLC38A3,SMAD2,TRAM2,SNX3,RAB2A,SLC25A4,SEC13,SNX14,RAB11A,ING1,ERLEC1,VAMP7,RAB6B,GRPEL2,APPBP2,POLDIP3,PPT1,RANBP6,RAF1,RHOB,SNX22,RANGRF,SEC22A,GOLPH3L,CDK5,STX1A,RAB6A,CTDSPL2,VPS28,ARL4D,RAB11B,RAB31,STRADB,SLC25A5,TRIM23,NUP35,LRRC8D,CTTN,ANKH,GPR89A,SLC22A12,SPRN,TBC1D13,PEX3,TOMM20,VAMP2,TIMM23,RAB37,PLEKHA8,FOLR1,ATG3,CDKN1A,HSP90B1,EXOC8,ARF6,EXOC5,CASC3,SLC29A1,SLC35B4,TBC1D17,RAB9B,LMAN1,GJA1,RP2,SEC61A1,TBC1D5,EXOC3,RHCG,KIF3B,EHD1,NCBP2,SLC25A39,VPS4A,ABCC5,TAF7,GNPTG,SLC7A9,TMEM30A,TP53,ARF1,STK4,SVBP,TMED7,RPAIN,TOMM70,NETO1,LRRC8A,AZGP1,NUP42,SEC14L1,ARF4,COMT,TRAM1,ARHGAP1,SRSF1,SLC15A1,HSPA8,SCAMP5,SNX20,CHMP1B,LARGE1,CEP41,IPO8,UPF3B,RAB32,KPNA2,SRP54,SLC6A4,SAMM50,CLN8,AP1AR,SNX2,AGAP1,SLC35D1,RAB3C,CHCHD4,SLC15A2,ARCN1,SCFD1,CHMP4C,PPARG,RBM15B,LIN7C,DESI1,ANKRD50,YIF1A,RAB39B,BET1,RPL23,CCDC22,RABIF,CD3G,GLE1,TMED5,GABARAPL2,MLC1,UFD1,CHMP5,FYTTD1,SLC35E3,SLC25A12,STX12,CALHM3,CETN3,SLC1A2,RHAG,KDELR2,RAB3D,SLC1A1,RHCE,VPS26C,IFT25,AP1M1,MAGOH,UCP2,RAB5C,SLC18B1,RFTN2,ENY2,SNX5,ROMO1,NFKBIA,CAMK2G,NSG1,CALR,SNX18,ABCB1,VPS26A,TMED4,GABARAP,FKRP,SELENOS,SLC25A31,VPS39,PPP3CA,FAM53B,SLC6A1,ARFGAP1,PEX26,LMNA,AKT1,AIFM1,PRKCE,SYVN1,KPNA6,FAM91A1,TOMM40L,RAMP3,RAB27A,TUBA1A,DERL1,BCAP29,SLC4A8,TSG101,STXBP1,ATP8A1,DDX39A,VLDLR,STX7,SLC25A26,TGFBR2,ARRDC3,NUP50,NUP153,ATG4C,SYNRG,CARTPT,CPE,SNX12,CCHCR1,CYB5R4,XBP1,FHIP1B,SEC61B,TIMM8A,AHCYL1,LAMP2,TOM1L1,IL6,EIF4E,SEC22C,TRAF3IP2,ERP29,CHMP1A,DDX39B,CETN2,DNAJC27,BBS5,ACVR1C,G3BP2,THOC6,GPM6B,GLTP,RAB23,MYO6,MACIR,MX2,SLC6A12,KPNA1,ARL11,SLC7A1,COPE,DUOXA2,LRRC8B,SNAP29,CLIP3,MIR130B,MIA2,GRM1,SLC1A3,FLOT1,SNAP91,VPS33A,VPS26B,TNPO2,AP1G2,TMED1,AP1S2,HSPD1,CPLX3,CD36,CHMP2B,VPS18,SLC32A1,SNAPIN,OPTN,SCAMP2,SLC35C1,XPOT,CHMP2A,EDNRA,TXNIP,TIMM29,SLC25A42,SAR1B,PEX5L,RHBG,SLC35A2,SFN,AQP11,HM13,PPP1R10,CACNG3,SFT2D2,TIMM17A,SMURF1,FAM53C,ILDR1,SLC38A7,DNM2,ABCC2,ATG7,MCL1,GUK1,EXOC1,NUP37,VMP1,EIF4A3,RILPL2,TIMM13,RAB33B,TFRC,NXT2,YKT6,CLTRN,SEC63,SLC7A11,ATG16L1,UBAP1,ATG4A,SPTBN1,CD63,KCNJ10,XPO1,ZDHHC17,HDAC6,LIN7B,TESC,S100A8,SELENOT,ZC3H11A,STX16,STX11,TMED9,GRPEL1,SYK,RINT1,CLU,ARFGEF1,RAB14,DERL2,SCG5,KCNJ8,DRD1,CACNB4,SLC16A10,TIMM8B,IGF2BP1,NHERF1,TRAM1L1,SRPRA,MRPL18,CBLN4,PML,NUP62,SLC35B3,NECAP1,EXOC2,EHD3,ARL6,SLC25A44,TRMT10B,VPS54,PICK1,VAMP3,GRM2,YIPF5,RAB35,VIP,RAB19,SLC25A20,STX6,SNAP23,CD2AP,SLC12A2,USE1,NDP,DNLZ,VPS16,FXR2,RAB5A,TSPO2,GPIHBP1,NEO1,SURF4,ARL4A,THOC1,HBA1,STX10,RAB8B,TOM1,PHAX,MAGOHB,ZFAND2B,STX5,ARFGAP3,SEC23A,CD47,PAFAH1B1,SNX10,NUP107,RAB22A,SERINC3,ZMAT3,SLC25A23,PHB2,ABCG2,HIKESHI,SQSTM1,LEP,RAB40AL,PARP11,SLC6A11,STX18,HNRNPA2B1,CHTOP,OLFM2,PPID,DAG1,TOMM6,SLC38A2,SEC61A2,SLC38A1,KDELR1,CTSA,SNX24,SYS1,SNX17,SEC62,MECP2,GOLGA7,SFXN1,AP2S1,STX17,TOMM7,AP3S2,NTRK2,TIMM21,SLC52A3,BET1L,TMED3,BICD2,SNX11,SHOC2,PIK3R2,SNX1,AGK,EHBP1,RAN,PIK3R1,SLC6A6,SNCG,ALYREF,MTX2,SLC25A32,TRIM3,MIR301B,CPLX1 |
| 1.851e-17 | -38.53 | VDAC1 (voltage dependent anion channel 1) | protein interactions | 7416 | 494 | 226 | 19454 | 5460 |
ATP5F1B,ESR2,VDAC2,LMBR1L,BST2,CKB,H2AZ2,CHTOP,H1-10,ICAM1,SERPINH1,ZMPSTE24,MYC,BAG3,EMC1,NDUFS2,EEF1G,SSR3,PHB2,ADRB2,BOLA2B,SAP18,ITGAV,GNB4,XRCC5,HDAC5,RAB5A,AKAP1,ACAA2,PPT1,UBAC2,CAV2,PIH1D1,TOMM22,MRPL12,RAB1B,CORO1C,AGR2,RAB5C,NDUFV2,DDRGK1,RUVBL1,RPL28,HNRNPDL,PAK6,PABPC1,CCT8,EWSR1,RTCB,PDHA1,TOP3B,TUBA1A,EEF2,KCTD9,PRKCE,SF3B6,UQCRC2,CSNK2B,MACROH2A1,CISD1,ATP1B3,ATP1A1,FGFR1OP2,RAB2A,SUGP1,TOMM20,HSPA5,RPL27,BAP1,BANF1,RNF113A,PRDX6,RPA2,SAMM50,GPR35,FGFR1,ACACA,CYC1,DKC1,MYL12A,SURF6,COQ8A,SSBP1,NDUFB4,COX4I1,FLRT2,MCL1,CD4,H2AC4,TSPO,DPP4,COX5A,TPM3,ATP1A2,FKBP8,MAP1B,SLC25A11,ATP5PF,BCAP29,CBX3,RNF8,ATP5PB,MTCH2,FAM162A,RPL35,ACTB,CHCHD3,MAD2L2,GNB1,ERH,ARF1,CYB5R3,ATP1A3,LMNB1,DCAF4,YWHAZ,BAX,RAB11A,TOMM40,ATAD1,FBXL4,ATP5MK,NMRAL1,HADHA,PSMA3,ATP5PO,ELOVL1,SLC25A3,NDUFA5,PGRMC1,PRDX3,NOP58,SPTAN1,PPIA,NDUFS8,EGLN3,ERLIN1,PHB1,OCIAD2,HP1BP3,ATP6V1A,TRAF6,PPM1B,RNF139,BCL2L1,STOML2,UFM1,ETFA,ATP5F1D,TRIM37,SSRP1,SAR1B,HSPD1,SCYL2,SLC25A5,EZH2,RAB19,RPN1,CHMP4C,STX12,RAF1,ERLIN2,MGST3,NDN,LDHA,COPE,TXN,RAB14,SLC25A4,SH3BGRL,TECR,DYNLT3,VIRMA,CCNF,STUB1,TUBA1B,NRP1,MAPRE1,NDUFB10,ATP5F1A,AR,PDHB,DAD1,RPA3,SIRT7,MGAT4B,GPX4,SQSTM1,RTN4,CDK1,HSP90B1,STOM,GRM2,METTL14,NOL7,MEST,ATG16L1,UBA52,EEF1E1,UQCRC1,GABARAPL2,CDK7,ALCAM,TOP1,ATP5PD,CAV1,ZBTB2,AIFM1,RPL12,NME2,MOV10,BAK1,SLC25A46,ATP1B1,THRAP3,MDC1,GALNT2,FAF1,RAB1A,SFXN1,NDUFS3,SLC25A20,ILF2,EEF1A1,PPIF,AGPAT5 |
| 1.977e-17 | -38.46 | HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1) | protein interactions | 3178 | 886 | 363 | 19454 | 5460 |
SRSF1,EED,MIR214,MIR143,MIR29C,MRPL9,AGR2,MIR140,HSPB1,RBM3,PABPC1,RUVBL2,RTCB,MIR155,POLDIP3,HNRNPDL,MSX2,TNPO2,PAIP2B,NFKBIA,SF3B4,GTF2F1,ATP5F1B,SNRNP40,PPP5C,PAPOLA,H1-10,CHTOP,RBM27,ICAM1,MCAT,SNRPA,SLU7,XRCC5,HDAC5,HSPA8,YAF2,HNRNPA0,STAU1,MRPS7,PABPC5,RPL27A,SUFU,TSHR,MRPS18A,PIH1D1,NCOA5,SYNCRIP,ARL4D,CD4,TMPO,RBM42,DKC1,CDC5L,COPS5,SNRNP70,MIR200A,MRPS18B,MIR16-2,MRPL47,H2AX,GDE1,DNAJC2,RPS3,MRPS28,KCTD9,ROCK1,SMURF1,CSTF3,SRC,SRPK2,DNAJC10,RC3H2,MIR10B,HNRNPH2,EXOSC4,RNF113A,UBE2K,RBM22,RNASE1,MIR107,HSPA5,MIR29A,MRPL10,MAEL,RPA2,EIF2B3,ZNF326,MIR21,GSTP1,HEXIM1,MYEF2,PHB1,TSG101,MIR141,CCAR2,CSF2,PRPF19,PRDX1,CRIP1,HMBS,MRPS35,DDX23,TRAF6,MIR1-1,AHSA1,BCL2L1,G3BP1,TRIM37,SRSF4,FEN1,GTF2E2,EZH2,CYB5B,FOXP3,SNRPB2,CUL2,CUL3,RBM15B,MYO6,LMNB1,NMRAL1,G3BP2,MIR106A,WDR77,MIR106B,RCHY1,TOP1,CALR,RNF14,HDAC6,GLO1,HSPE1,MRPL22,TBK1,YTHDF2,MRPL11,MIR200C,EEF1A1,GGCT,MIR20A,MIR17,ILF2,SRP72,MIR16-1,STUB1,EIF4A3,RTRAF,UBE2I,PTEN,LDHA,CTSD,ATP5F1A,NONO,MIR145,IVNS1ABP,PNO1,PRPF4,MTDH,GTF2I,AATF,ATG16L1,RBFOX2,BRINP1,MX1,MIR1-2,PRMT2,JUP,LMNA,GRM2,RPLP0,PDCL,FUBP3,RBM5,WDR82,HNRNPL,SNRPA1,SNRPD3,AASDHPPT,MIR9-1,HSP90AB1,IFI16,WWP2,XPO1,DDRGK1,CTNNB1,MIR31,MIR221,DDX1,MIR9-2,LSM14A,EWSR1,MIR206,HNRNPF,CCAR1,MIR222,RPS7,EEF2,PDHA1,CMTR1,MIRLET7B,PRMT5,MRPL13,MATR3,APEX1,APOBEC3B,MYC,HNRNPC,HNRNPAB,PSMD1,BTF3,SNRPB,CPSF2,CIRBP,FBXW11,NGRN,DDX39B,DDX5,TRA2B,UFL1,PHB2,EEF1G,MTF1,PPT1,MAP2K1,ACAA2,EIF4B,MRPS9,SSBP1,ALYREF,CAND1,MIRLET7G,MALSU1,MYL12A,MIR429,DPP4,CD81,GAPDH,H2AC4,MRPL52,DHX9,MIR9-3,H3C1,NEDD8,HNRNPK,MIRLET7C,MEPCE,ATP5PB,STRBP,TP53,INSIG2,RPSA,CAPN2,NUPR1,PSPC1,SF3B6,CALML5,CARS1,CFL1,CFL2,IGF2BP1,PDCD4,RBM7,CDKN2AIP,UBE2H,BAP1,PGK1,PPP1R26,RPS15,MIR34B,CDC42,WWP1,TFIP11,MIR7-1,IFIT2,MIR7-2,PSMB4,RPLP2,SRSF10,PPIA,DHX15,HMGA1,HNRNPA1,MRPL18,DROSHA,HNRNPD,HSPD1,GADD45A,HNRNPA2B1,SRSF7,TNF,RPS27A,SSRP1,B3GNT2,RBM12,ACTN4,PPP2R1A,SNRPD1,SNRPD2,RPS9,EIF4A2,ACTB,MIRLET7D,CLIC4,USP5,PRRC2A,PRPF31,MIR98,MRPL16,YWHAZ,BRCA1,MIR363,RPS5,HSP90AA1,PSMA3,MRPL57,MIR25,DCUN1D1,MRPL50,CDK9,MDM2,MRPL24,MRPS23,CWC15,GRSF1,MOV10,MIR34A,FAF1,RAB1A,NKRF,VRK1,MRPS18C,RIGI,SMN1,FBP1,MIR15A,TOPORS,CCNF,TUBA1B,ENO1,GTF2A1,ALB,MSN,NDN,PNP,RPL26,DNAJC8,PAIP2,DNAJC19,RPA3,PHYHIP,MIR205,CLK1,MIRLET7I,MIR34C,MIR7-3,FBXW7,MEF2A,SF3A1,CDK7,METTL14,PICALM,HNRNPH3 |
| 2.035e-17 | -38.43 | TGOLN2 (trans-golgi network protein 2) | protein interactions | 10618 | 1581 | 592 | 19454 | 5460 |
EDEM1,KARS1,USP15,IGFBP4,SLC35A1,TRAPPC3,CAMLG,STT3A,AIP,GLT8D1,SDHB,EEF1B2,SURF6,ILVBL,SELENOI,TMPO,TWSG1,FCHO2,CNPY4,GNPTG,DNAJC1,GDE1,UBIAD1,MTCH2,SNAP29,RRM1,TBC1D4,SPRY1,TSPAN3,SELENOF,TMEM165,RBM34,BMPR2,TFRC,MAN1A2,SLC16A1,RAB13,ABCE1,ERO1A,RUSF1,PCYOX1L,NAE1,UST,SLC6A8,FKRP,L1CAM,SRPRB,NCAPG2,CHPF,SLC6A6,C9orf72,SNX5,CALU,ATP1A1,DNAJC10,HFE,STX10,BCCIP,SC5D,NTPCR,GALNT4,TRAM1,HECTD1,SERPINI1,VPS54,VIPAS39,GALNT1,RPA2,CD46,UGDH,TMX2,HSPA5,AIF1,TBC1D5,FAM20B,PPIB,CST3,GSTM3,YWHAB,DRG1,TGFB2,SLC39A13,TRAPPC10,DIPK2A,ADGRG1,PTK7,LANCL1,VAMP7,TOR1B,LYAR,PCSK9,KIF2A,CCDC134,ARFGEF1,RANBP1,NETO2,CRELD1,MTA2,KDELR1,NUDT19,PDIA6,SEC11A,DNAJB4,EFNB1,CCT8,RINT1,FKTN,FSTL1,TMEM87A,POLDIP3,TIMP1,TMEM38B,TMED5,SLC38A1,FTSJ3,GCC1,PLA2G15,LAMTOR1,SPCS3,BST2,OAF,FAM83B,ATP6AP2,FBXO22,ATP5F1B,CD59,CNPY3,FDFT1,OGFOD3,FAM8A1,SIGMAR1,UBAC2,FKBP14,AKAP1,P4HA2,RER1,PRCP,EMC1,MPG,EMC4,RELL1,EI24,CALR,ESYT1,SLC2A1,SEC23A,CDCA3,NELL2,EHBP1,SRPRA,HACD3,CAV1,G6PD,TRAPPC6B,ATP5PD,PRNP,CD151,ARF6,ALCAM,LBR,ALG11,SLC29A1,MRPL11,CCDC47,POMT2,CASK,MSRB3,HSPA13,DMAP1,TMX3,SNAP23,EMC2,SHISA2,BSCL2,ZC3H11A,DLG1,LTBR,SLC25A10,STX8,PRDX4,GALNT2,CTNND1,ARF4,DEPDC1B,SEC13,CTSD,EPHA2,XPOT,NAPA,CHORDC1,TMEM106C,GANAB,FBLN5,SMAP2,VAMP3,SELENOT,SEC63,TECR,VKORC1L1,CD47,SNX3,RAB14,HACD2,CNP,FUT8,CLSTN3,CPSF4,TM9SF1,EPHX1,HSP90B1,TMX4,P3H1,JUP,MTDH,ITGA2,SQSTM1,NXPE3,FLCN,MGAT4B,CSTB,FADS2,LRRC8D,SLC5A6,USP8,IL1RAP,TPST1,WDR11,EMC6,MRPS35,PRPF19,CD58,TMEM164,CDH13,HP1BP3,THY1,TSG101,GJA1,FAM3A,WDR6,FOLR1,SELENON,TMEM248,NPC2,ERLIN1,CACYBP,SNX1,SNX2,OCRL,LGR4,EMC10,TPD52,MARCKSL1,PLD3,CYB5B,CTSA,VPS33A,STIM1,VAMP2,ERP29,SLC39A7,PLSCR1,SIAE,HS2ST1,AP1M1,RRAGB,MYORG,LAMB2,EMC8,GGH,NOP16,KDSR,VEZT,WDR20,ATP1A3,SLPI,FZD6,SLC30A7,AP2M1,PIGK,CYB5R3,CPSF1,RPL19,CHP1,RBBP4,TSN,DYNLL1,MB21D2,RAB6A,PRDX3,FAM234A,TMEM231,FAM3C,ATP5PO,BET1L,HADHA,CXCR4,LUM,PSMC1,GPC1,NPTN,EDC3,TPM3,GAPDH,ATP6V1D,ADGRE2,MAP4,TRAPPC2L,SLITRK5,NT5DC1,XXYLT1,EXT1,SLC39A10,RPL32,ITGA6,LMAN1,STX6,SLC38A2,TMED9,VTI1B,NDST1,YIPF4,FURIN,GNAI3,CBX3,SURF4,BCAP29,GLCE,MAP1B,LPCAT3,CTSC,EDEM2,RAB3B,HNRNPK,AKAP12,RHBDD3,GORASP2,ARHGAP21,ARL6IP6,MTPN,NPTX1,NUDT4,CSGALNACT1,ENDOD1,SNX14,ATP1B3,INTS12,B4GALT1,SEC61A1,TRAF7,NECTIN2,ALG2,CDIPT,TXNDC12,LEMD3,CHPF2,SSR1,DLAT,ARFIP1,ITM2B,LRP10,RAB29,LIN7C,CLU,TENM3,QPCTL,CTNNB1,YWHAG,RAB5C,PTDSS1,LAMP2,PROS1,DDX1,BPNT2,CRTAP,DEGS1,AK2,SELENOM,STX5,PSME2,SSR2,COCH,EEF2,TMEM59,SNAPIN,NCSTN,HEXA,HGS,PLS3,SCPEP1,EWSR1,ABCF1,CYP1B1,RAB18,VAMP8,FKBP2,SLC35A2,RUVBL1,SLC20A2,ROCK2,PGAP4,EPHA4,TFPI,GXYLT2,SLC30A5,LRRC8C,CPSF2,STX16,CUTA,ST3GAL1,ST3GAL2,SERPINH1,ZMPSTE24,PDF,LRP12,RCE1,PRMT5,GGT7,VDAC2,APEX1,TAGLN2,EDEM3,MRPL12,BORCS6,IL6ST,SEC62,MTMR6,CAV2,PPT1,LMBRD2,THBS3,MIA2,TAPBP,TMEM106B,BMPR1A,JAGN1,SLC37A4,CERS6,ITGAV,GOSR1,ATP1B1,DAG1,HM13,RAB3A,C1GALT1C1,TRAPPC4,CHID1,LDLR,ST6GAL1,PTPN1,MSMO1,EXTL2,DERL2,HTRA1,SEMA3C,NRM,TOR3A,ITGB8,TRAPPC13,VAC14,PTGES,IGF1R,ERG28,TMED1,TRAPPC1,RAB1A,VPS16,RIGI,B4GALT7,ERLEC1,HMOX2,CSGALNACT2,CNTNAP1,GGCX,SMAD2,AP2A1,LRP6,NRP1,ARFGAP3,RPS12,DNASE1L1,NEGR1,EIF2AK2,CTNNA1,GXYLT1,GNAI2,FERMT2,B3GALNT1,MGST3,COPE,SYNRG,SLC35E1,ARHGAP1,CCN3,JMJD8,SEC22B,RABL3,MET,MEST,GOLGA5,STOM,PICALM,SLC12A2,AP1AR,SPCS2,RTN4,GLIPR1,RPA3,DAD1,NF2,YKT6,COL3A1,PIK3R1,PDIA3,ST3GAL4,TMEM30A,ITPRIPL2,ELP6,ATP6V1A,MFSD5,DHX15,NUP35,IFNGR1,DIPK1A,ERLIN2,NEU1,DCAKD,JPT2,STX12,ITGB5,NME1,BZW2,RIMOC1,RPN1,SCYL2,GPAA1,NEK9,COPS4,AHCYL1,SACM1L,TMED7,GTF3C3,SEMA4C,SMARCE1,TMED4,TM9SF4,NIBAN2,VMP1,FAM219A,SLC7A11,SCFD1,PFDN2,CNIH4,SEC61B,FAM91A1,ACKR3,USP5,B4GAT1,MAT2B,SUSD6,ABHD12,LAMTOR3,BMP1,B4GALT4,B4GALT3,SPCS1,RANBP6,PRDX2,LRRC8A,PGRMC1,NOTCH2,CA12,TOR1AIP2,GINM1,RRAGA,ARCN1,PRSS23,FKBP10,HEXB,EMC9,VPS18,ISOC1,VAPB,KCTD12,EMG1,TXNL1,SPOCK1,DNAJC3,ATP2C1,STX7,NOP53,TMED3,CYFIP2 |
| 2.089e-17 | -38.41 | RPS3 (ribosomal protein S3) | protein interactions | 6188 | 660 | 285 | 19454 | 5460 |
LYAR,TCP1,SUMO2,RPS10,HNRNPL,SRSF1,RBM5,EED,AGR2,DRG1,MAGOH,WWP2,RPL6,IFI16,NGDN,DDRGK1,CTNNB1,XPO1,KRAS,H1-6,RPL28,RPS4X,PABPC1,RPL31,RAB4A,GLE1,RPL18,RPS23,RPS7,MSX2,SOX2,TRAF2,H1-3,ESR2,RPL10,NFKBIA,DKK3,CCT2,H1-1,COP1,ICAM1,RPS26,SFN,HNRNPAB,MYC,BTF3,STAU1,HNRNPA0,UFL1,RPS28,PYM1,DDX39B,DDIT3,HDAC5,HSPA8,PPT1,LXN,ADSS2,CSNK1A1,PIH1D1,EIF4B,FGF17,PAFAH1B1,RPL27A,MTF1,RPS27L,FZR1,CAND1,RPS16,CDC5L,RBM42,RPL32,SYNCRIP,SNRNP70,RPL24,TUBG1,RPL10A,TSNAX,RPS2,CDK12,RBM17,ENY2,GAPDH,CSNK2A1,CD81,COPS5,IMP4,TOLLIP,NEDD8,RPL17,SRSF12,MEPCE,MAP1B,DHX9,RPL3,NHERF1,DNAJC2,PIK3CA,TFCP2,RNF8,RPSA,INSIG2,TP53,NAA35,STRBP,SRFBP1,UBL4A,H2AX,RPL10L,SMURF1,CDC20,PSMA6,PSPC1,FGFBP1,TRIM23,RC3H2,EIF3G,SPOP,RRP7A,UBE2H,ATP1A1,RPL7A,CCNB1,MAT2A,ZSCAN25,RPS17,RPS15,HSPA5,NLE1,RPL27,BAP1,RNF113A,EXOSC4,RPA2,HECTD1,UBE2M,HEXIM1,SUMO1,FGF13,CFTR,RPL7,PHB1,RPL9,FOLR1,RPL8,RPLP2,RPLP1,HP1BP3,GJA1,CDK5RAP3,BCL2L1,RPL23,RB1CC1,RSBN1L,HNRNPD,AHSA1,UBXN6,HNRNPA1,TRIM37,TNF,G3BP1,EMC8,TRIM26,RBBP7,AHCYL1,RAD21,SAR1B,RPS27A,HNRNPA2B1,SLC25A5,TRIP4,RPS24,PPID,EZH2,SART3,RPS11,B3GNT2,PPP2R1A,ACTN4,RPL29,ACTB,RPL35,DYNLL1,MRPL23,RPL19,FAU,SEC61B,RPS9,RPL37A,BRCA1,ZCRB1,DCAF4,RIT1,RPS5,HSP90AA1,CUL2,CUL3,ACO2,RPS29,ZNF668,YTHDF1,G3BP2,COIL,WBP2,NMRAL1,CRY1,EMC9,PPARG,WDR77,H1-5,RPL35A,CDK9,MDM2,KRR1,ARL10,EFNA3,SRP14,RPL12,PWP2,PRR3,MPHOSPH10,NME2,CALR,GRSF1,NFKB1,MOV10,HDAC6,VRK1,HUWE1,EIF3E,RNF20,RPS13,FAF1,IGF1R,RPL23A,HAPSTR1,TNFAIP8L1,LLPH,SRP72,ILF2,TRIM6,FBP1,RPL15,APOBEC3D,RPL13A,COPE,NDN,RPL22,VIRMA,DYNLT3,SH3BGRL,METAP2,CCNF,RPS12,PTEN,RPS20,TRIM24,CDC73,AR,USP14,TUFM,PPP1CC,RPL26,FBXO7,ATP5F1A,NUCKS1,RPL4,HMGB1,FBXW7,NF2,AATF,PIAS1,PNO1,RPA3,METTL14,ZCCHC17,H2AC7,CDK1,ZNF574,RPL26L1,RPLP0,UBA52,ATG16L1,RPS14,CDK7 |
| 2.426e-17 | -38.26 | RPS8 (ribosomal protein S8) | protein interactions | 6202 | 601 | 264 | 19454 | 5460 |
RPL35A,DCUN1D1,MRPL50,CDK9,MRPL24,NOP9,RPL12,SRP14,RCHY1,KRR1,CRBN,MPHOSPH10,GRSF1,SPATS2L,EMC4,HDAC6,PAK1IP1,HUWE1,VRK1,FBXO25,RPS13,MRPL22,EIF3E,RPL23A,LLPH,ILF2,MRPL49,MRPL51,SRP72,FBP1,MRPL11,EEF1A1,RPL15,NDN,RPL13A,VIRMA,RPL22,CCNF,EIF4A3,METAP2,GSK3A,PRKRA,RPS20,RPS12,ZMYND19,RPL26,TUFM,DNAJC8,PPP1CC,AR,NPM3,DGCR8,MRPL17,RPL4,HMGB1,FBXW7,AATF,UTP23,MRPL20,RPA3,SIRT7,MRPS34,GRM2,ZCCHC17,METTL14,RPLP0,RPL26L1,ZNF574,RPS14,UBA52,TPT1,FTH1,CDK7,NOP58,RPL7,RPL8,RPL9,FOLR1,PHB1,RPLP1,HP1BP3,RPLP2,MRPL18,MRPS26,RPL23,PSMD3,MRPS35,ATG7,HNRNPA1,TNF,EMC8,G3BP1,TRIM37,RPS27A,SLC25A5,TRIP4,RPS24,MRPS11,TMEM147,EZH2,CHMP4C,RPS11,SART3,B3GNT2,DLG3,OTUD6B,PPP2R1A,MRPL23,RPL7L1,RPL35,PRRC2A,RPL19,RPL37A,SEC61B,RPS9,BRCA1,ZCRB1,RPS5,RIT1,CUL3,NOP16,CUL2,ZNF668,MRPL16,PDE4B,RIOK2,RPS29,NOP53,MRPL57,PSMC1,G3BP2,NMRAL1,PPARG,EMC9,RPS16,CAND1,FZR1,RPS27L,DKC1,RBM42,TMPO,CDC5L,SURF6,MRPS9,RPL32,TUBG1,RPL24,SNRNP70,NOL12,CDK12,RPS2,RPL10A,ENY2,CSNK2A1,COPS5,CD81,E4F1,API5,NEDD8,MRPS33,MEPCE,RPL17,SNIP1,MRPL52,RPL3,TFCP2,RBM34,DNAJC2,IMP3,UBL4A,KBTBD4,MRPL47,TP53,RPSA,ADRM1,RPL10L,SMURF1,SRPK2,RSL24D1,RPS3,PSPC1,RBMX2,MECP2,SPOP,EIF3G,ATP1B3,RC3H2,UBE2H,RPF2,RPL7A,RPS17,ZSCAN25,RPS15,MRPL41,MRPL40,HSPA5,RPL27,BAP1,RNF113A,RPA2,HEXIM1,UBE2M,UTP15,TFB1M,KLF4,MRPL10,FGF13,CFTR,RPS10,RBM5,EED,AGR2,MAGOH,DRG1,IFI16,DDX50,WWP2,RPL6,MRPL9,XPO1,CTNNB1,DDRGK1,NGDN,KRAS,RPS4X,RPL28,RPL31,PABPC1,RPS23,RPL18,RPS7,MSX2,RPL10,CMTR1,MRPL13,MRPS25,FTSJ3,ATG3,RPS26,ICAM1,COP1,NSA2,MYC,SFN,BTF3,PSMD1,UFL1,STAU1,SSR3,MRPS7,PYM1,RPS28,SF3B1,HSPA8,MRPL34,HDAC5,ADSS2,MRPS18A,EIF4B,PIH1D1,MTF1,RPL27A,PAFAH1B1,MRPL12 |
| 2.494e-17 | -38.23 | HMGB1 (high mobility group box 1) | protein interactions | 3146 | 443 | 207 | 19454 | 5460 |
RBFOX3,ZNF24,CXCL12,RASSF4,GAPDH,CSNK2A1,NEUROD6,BECN1,RPL24,RPL10A,RPS2,RPL32,UBE2N,CD274,PLG,RPS16,RPSA,TP53,SIX5,AGER,CBX3,MAP1B,RPL3,MRPS18B,HNRNPK,H3C1,RPL17,MNAT1,FOXA3,RPL7A,SMARCA5,RPS17,UBE2E3,MECP2,KCNJ2,UBE2H,ZNF330,RPS3,MACROH2A1,MRPS21,HPF1,ZNF326,RPA2,RAG1,PRKCA,DYRK2,HEXIM1,NBN,BAP1,RPL27,DLAT,TLR2,TWNK,RPS15,HSPA5,ASB1,RPL6,DDRGK1,NGDN,CTNNB1,XPO1,YWHAH,AGR2,POU5F1,SRSF1,RPS10,PGR,MSX2,EEF2,RPL18,MOB3C,ZRANB2,TOP2B,RPL31,TRIM11,EWSR1,PSMA1,POLDIP3,CCAR1,RPS4X,HNRNPC,MYC,CREBBP,UFD1,CHTOP,CRMP1,IRF2,TAX1BP1,PTPRZ1,RPL10,POLR2B,LRIF1,ZC3H14,RPL27A,ZNF428,AKIP1,MAP2K1,CSNK1A1,RPS28,FOS,SMARCD3,YAF2,EP300,HSPA8,SF3B1,TRA2B,UFL1,MRPS7,MT2A,TLE1,NFKB1,DAG1,SRP14,H2AZ1,TFE3,RPL12,RB1,PRNP,MRPS23,PHF23,RPL15,RAD23B,SOD2,TLR4,FAF1,EMC2,RPL23A,ERG28,THRAP3,HUWE1,CTNNBL1,PSEN1,RPS13,KPNA6,AR,RPL26,PPTC7,LGALS8,CDC73,XPOT,EIF4A3,CTTN,STUB1,RPS12,RPS20,UBE2I,GTF2A1,RPL13A,RPL22,VIRMA,RPS14,SAP30BP,CDK1,MRPS34,LMNA,MACROH2A2,KRT7,RPLP0,SOD1,RPA3,SQSTM1,MIEN1,HMGB1,RPL4,MRPS35,HR,PDIA3,HMGA1,TRA2A,DDX23,LHX2,MRPS26,DNM2,RPL8,RPLP2,HP1BP3,BUD31,RPL7,OCRL,SRSF10,HOXB1,ACTN4,RPL29,CHMP4C,NGB,RBPJ,RPS11,SRSF7,RPS24,SSRP1,USP13,RPS29,SMARCE1,DCAF4,RPS5,HSP90AA1,RPS9,RPL35,RPL19,AGTRAP,MAPKAPK5,H1-5,CXCR4,TXNL1,ATP5IF1,PPP2R3A,COIL |
| 2.569e-17 | -38.20 | EMC4 (ER membrane protein complex subunit 4) | protein interactions | 51234 | 282 | 146 | 19454 | 5460 |
CRELD1,RPS23,PDHA1,DNAJC25,SERPINA3,CYB5R1,EEF2,RPS7,NAA15,EMC10,RPL28,PRPS1,HNRNPF,EMC8,GJB1,PRPSAP1,JAK1,PCNA,TRIM21,RTCB,RPL31,SCYL2,RHOG,PPIB,EMC6,NT5C2,PRDX1,CLPX,NDUFS8,PPIA,UQCRH,ERLIN1,HSP90AB1,DHX15,EIF2S1,TCP1,RPL7,MAGED2,ATP6V1A,RPLP1,CYB5A,RPLP2,RPL9,PLAC9,MED23,EMC9,OTULINL,PGRMC1,TOR1AIP2,DNAJC22,EMC1,SERPINB6,PHB2,SCFD1,ZMPSTE24,CHTOP,HSD17B3,PRPF31,RPL10,ESR2,APEX1,ATP5F1B,PSMD6,SPCS1,PRMT5,RMDN3,POLR3B,RPS9,LMBR1L,PSMC3,NDUFS3,RRM1,CCDC47,CCT5,RPS13,FKBP8,EIF3E,ADIPOQ,RPL23A,EMC2,HSD17B10,PSME1,RPS2,OSBPL8,NME2,POR,RPL24,ESYT1,SCGB1D1,GAPDH,MOV10,CALR,PGAM1,SLC25A46,EMC4,TMPO,G6PD,DNAJC1,RPS16,CPNE1,SEC23A,PTPN1,HACD3,COX4I1,RPL32,RPLP0,CYC1,RPA2,UQCRC1,CDC42,ST7,GTF2H4,SEC22B,PDHB,STK38,GNRH1,PGK1,DLAT,MTDH,ARPC2,PRDX6,RPA3,MME,RPL27,TRIM3,NAPA,IVNS1ABP,LACRT,CSGALNACT2,HMOX2,MAT2A,NDUFAF2,RPL7A,SEC13,RPL22,SEC63,TMOD3,RAB14,RPL13A,SLC25A4,CMBL,MSN,RPS12,UQCRC2,ENO1,EIF4A3 |
| 2.712e-17 | -38.15 | large_intestine | COSMIC cancer mutations | large_intestine | 16528 | 4808 | 16828 | 4835 |
LY6G6C,RHCE,TMEM106A,ANGPTL2,PHAX,BAALC,FKBP10,RIMKLA,EXOC1,GPX4,SEC62,FGF12,SNRPD3,LAMTOR3,ZNF175,TP53INP2,GPSM3,GOLPH3L,TNNT2,STK11,COMT,TESK2,RPS27L,SEC61A2,ELAVL4,MEF2C,DRAP1,LRRC4,LITAF,ARFGAP3,ARL4A,SYS1,IL1B,GPR26,PLAA,RPRM,BAP1,DOHH,FUT1,ALG2,MBLAC2,PHKA1,RPL10L,COG1,SCYL2,MCHR2,KLHL7,OR51A4,DET1,ZNF330,CSTB,GTF3C3,RNF14,SAT2,PRRG1,GPNMB,RAF1,IRF6,DNAJC10,RGMA,RAP2C,LAMTOR1,ADNP,DDX5,EIF4A3,CYTH1,PDE9A,SLC1A1,CCDC71,CCHCR1,RPS5,SNAPC2,SLC22A12,FOXP2,CYP17A1,UBE2F,UBN1,TPSG1,NDUFA12,NUDT5,DNAJC25,EGFL8,ARL15,ILVBL,AZI2,KATNAL1,TNFRSF14,TXNRD1,TMOD1,KCNMB2,GTPBP1,RPS11,GSTK1,NAE1,NLRP1,CNPPD1,GZMK,TMEM199,FBP1,CENPP,RP2,STX12,GCC1,LRRN1,CD1B,DNAJC27,KDSR,ZFAND2B,DNAJB6,AOX1,PSMA5,STARD13,B4GALT1,ATP1A1,CRKL,TGIF2LX,DEDD,BOLA3,PPM1G,CDC42EP2,FLRT2,TMEM209,GLYAT,GFI1,FCF1,MYD88,MRPL52,PLN,CD1D,E2F4,GLRA1,G2E3,QPCTL,TOPBP1,RBM18,RPL3,MTG1,PROM1,MRPS18A,C1QL3,TRIM11,VMO1,LCMT1,YIPF4,CSNK2B,TMUB2,RHOB,MAX,OR4K17,NRSN1,HOXB1,KCNMB1,TRMT1L,CD46,GABARAPL1,GNAI2,UCK1,CDC123,CBY3,PEX5L,SVOP,TM9SF1,COMMD2,MAGOHB,FAM118B,CBX5,MYCT1,ARL10,RERG,POLR3F,RPL35,FRS3,RRAS2,ATL1,TPT1,SNCB,ACTL9,GTF2A2,RNF20,GPR15,COPS7A,PPARA,STOML2,OTUD6A,MICB,TOR1AIP2,NUP153,RNF39,HDAC6,PBLD,TMEM176A,CNTNAP1,ANAPC13,EYA3,DUSP26,USP14,TSC22D3,NANP,TXNL4A,CISH,GNA14,CXCR6,AGPAT1,ZMYM4,EIF2S2,BTG1,CHMP5,ASB3,EDNRA,ST6GALNAC3,TBC1D24,SPOPL,SYT2,TMEM95,LEPROTL1,NR1H2,BMP1,PRPF31,PHB2,TTC1,MMADHC,SESN3,CDSN,ZNF692,SLC25A44,THY1,TESC,YWHAB,PSMD14,NFYB,SLC25A17,LRWD1,EEF1G,ARRDC3,ZCCHC12,STXBP6,DAPK1,PDE1A,LILRA1,TPBG,KCNQ5,CYB5R3,PLAC8,NDC80,SNAPC5,RPP21,RAB13,OR10G2,MAP1LC3A,SELENOF,RNF26,PATE2,CDK5,GNG3,MRPL51,NME4,FNTB,YIPF5,TOB2,SLC6A4,PDSS2,SFTPC,ZC3H15,SLC25A23,ODC1,DSN1,SHMT1,CYTL1,NDUFA4,SLC45A3,HEXB,SYNGR4,PPFIBP1,OAF,PKIG,MOBP,TSG101,MAMDC2,ADCY2,THBS3,TRUB1,CALR,SNAI2,DRG2,PRDX2,DPP4,HEXIM1,LMO3,UGP2,EIF2S1,MRPS33,LMBRD2,PAX6,STAT1,ZNF507,RPN1,CD151,KCTD9,TLR6,DLG1,P2RY11,IL3,CHRM1,MSX1,BVES,RAB14,GOLGA7,TMCC1,REP15,SDC4,WASL,CD79B,OR4N4,ZBED4,DYNLT3,SP4,TMEM31,PTN,SSBP1,KCNA3,F10,NDUFB7,NEK2,ZNF526,NDUFV2,RAB5A,PC,APOBEC3D,GNG5,TMEM14B,NIF3L1,RRN3,DHPS,UTS2,TLE1,ARL6IP6,HMG20A,BTF3L4,CYP27B1,PNOC,YBEY,NTPCR,IL15,MRPL10,MOG,LRRC57,PLSCR4,OSGEP,SCN3B,NMI,RIMS4,NDUFA2,IFNGR1,TPGS2,NUP50,NSFL1C,TMEM190,SCPEP1,OGN,PADI2,POLR2F,NDUFB10,POMT2,EIF4E3,MYOZ3,TCAP,RIC3,ARHGAP25,DES,PCDH9,ZRANB2,LIN7B,ZNF575,CCL20,MRPS7,ARHGAP5,VTI1B,FAM162B,GLT8D2,SPATA6,KLHL12,SERPINI1,IDO1,PPM1D,SLC25A28,SLC39A3,FLCN,MSL2,CXCL12,RSRC1,RPL35A,CD248,ZNF668,TNFSF13,FLRT3,STIM1,GRPEL2,LRIF1,TMC7,FTL,MTMR6,NEUROG2,LUM,CCDC85B,SEMA6C,ICAM3,UNC50,HMX2,CHST11,TUBA1A,YTHDF1,RPL7,CELF6,FCGR2A,NAA50,MED31,SH3BP5L,IFIT2,SECISBP2L,RAB33B,MCM3,CDC42EP3,RNF115,RASGRP3,ENTPD3,RCE1,MGAT1,RGS19,PSMD12,CKLF,CCT7,SLC25A11,PAFAH1B1,KCTD15,PDCD1,HNRNPD,MS4A7,CHRDL1,NLRP6,TOMM20,TRAF3IP2,PTGER4,BAHD1,DHRS7B,ZCCHC17,PSMB6,IZUMO1,PEG10,PIP5K1A,MORC4,CISD1,PIK3R3,LANCL1,MKKS,SLC35B4,TERT,METTL6,RASL10A,TUFM,GNG13,OR51M1,IFNA2,IDH1,KRTAP12-4,VPS28,MPZ,SRC,CD2AP,CD1A,LPAR1,HSP90AA1,HDDC2,FNDC9,PPIH,DCUN1D5,FOLR2,PDRG1,SOCS3,PTPN22,PGAM1,AP2S1,RNF121,UGDH,RPS13,CCSAP,EPO,ZNF280B,MMP21,EID1,CHCHD3,NFKBIB,CPNE1,GNB4,CNTN1,ZER1,ACTB,MATN4,DDAH2,LNX2,TYW3,SNX18,RFC2,DAD1,ZBTB2,MFN1,TAS1R2,CNR1,PLA2G12A,CAMLG,NPY,SLAIN2,NICN1,TMEM208,RAB30,RSAD2,GABRA2,COMMD5,SST,PFDN4,GSTM2,NAA35,UBFD1,PPP4C,PPIG,NRBF2,EFHD2,DNAJB2,PSMA2,GGT7,GRXCR1,TLR2,FGF10,HECTD1,DYNC1I1,LGR4,ARMC1,GABRB2,TFEB,SYVN1,HSCB,CES5A,CCDC122,PPP1R12A,IL6,GRID1,RERE,MORN4,GIMAP4,XXYLT1,RPAIN,UNC119B,TBC1D4,PSMC1,MED21,TTC32,PAIP1,SSRP1,OCIAD2,TWSG1,OR9K2,NDUFS3,HPGDS,RLN2,OSBP,GOLGA5,DNTT,SMC4,GTF2E1,TNNC2,OR8I2,AK5,RAB22A,CLVS1,FAU,CYP2F1,PSME1,KBTBD4,PNO1,AGAP1,SLC6A12,TRIM10,UBE2E3,UBE2M,PIR,MOSPD1,ELAVL2,OR5AP2,FCHSD2,ISCU,TM9SF4,TCEANC2,NUP37,LRRC1,USP5,MXI1,FERD3L,GPBAR1,ITGAV,LDHB,RPF1,FOXP4,TMEM182,RNF126,AKR7A2,AURKAIP1,FXR2,DRAM1,IL1RAP,VKORC1L1,SMARCA5,CNPY4,ELK4,FAIM,BAK1,ATP1B1,GPR85,PPP2R3A,SLC22A8,DRD1,SMAD4,SLC1A3,RILPL2,FZR1,GRAP,EPYC,SELENOT,PHC1,BLOC1S3,TAAR6,PLXNC1,UGT2A3,PHF12,ZBTB33,GEMIN7,BAG2,DCP2,MED17,NOB1,TMEM184C,IL13,EIF4E2,GRM8,UTP15,MCM8,HP1BP3,OSGEPL1,PACRG,TAS2R16,TLCD2,MT1A,CD38,PNMA2,ANKRD49,CAMK2N2,CUTA,RMI1,DLAT,RIMS3,KLRD1,FASLG,EIF3E,CTBP1,CDC42EP4,MSRB3,DDT,JUP,ALKBH3,EXT1,EXOSC4,BUB3,DNLZ,SNX5,SLMAP,CFL2,OR4N5,ZMYM2,CD52,CYP3A5,DCUN1D3,LMNA,PHF1,RNF41,ZNF7,PLP1,DCAKD,XPNPEP1,MGAT4B,TMEM74,IRAK1BP1,TIMM8B,TSHR,SLC25A20,AIG1,NEUROD6,INSM2,EIF2D,DYRK1A,DRP2,RAB31,STC1,OR8K1,KLHL32,SRGN,LIMD2,COPS2,TRIM27,EIF2AK2,C1GALT1C1,LGI3,GTPBP2,SFXN1,UBAC2,NME2,CD4,UBXN6,KCNF1,NR4A2,NOSIP,SLC25A45,TAS2R46,G0S2,OR5I1,SATB1,TRA2A,BEND6,PRMT5,GANC,ACO1,CACUL1,PPTC7,PCK2,RALGAPA2,DCAF4,PCSK2,ARHGEF6,SLC39A13,CYP4F12,CPE,CDC40,SCN1B,NDUFB5,TM2D2,OR52W1,SUB1,NELL2,DTD1,REXO2,GPHA2,POC1B,NTF4,LRTM2,CYB5R1,USP2,MYT1L,NOL7,SNX2,WFDC5,CAMK1,TACO1,NSA2,SSBP3,NXPH3,DEFB115,NOVA1,INPP5K,MCAT,NUDCD3,SEC63,IRF2,TM4SF1,BCCIP,PTTG1,ERP29,IKBKB,HELLS,MITF,LCA5L,HTRA1,KIF3B,HRAS,SYT4,WDR20,RPP14,TAGLN2,RPL13A,FAHD1,TRIM8,TFG,CYB5A,ELOVL3,MTX2,MAEL,CDK8,BSCL2,RNASEK,IQCF5,PHF23,COX10,CLVS2,VAMP3,WDR83,VLDLR,CRB3,DHRS7,TMOD3,SOX3,RPS4X,COX19,MAP3K12,RSPH1,ZDHHC15,FBP2,PPIA,LECT2,SLC16A4,POGK,ACOT8,TRIM52,HNRNPA1,NFE2,LRTOMT,NCKIPSD,DEFB121,CTSB,ALKBH2,SKA3,RPS29,GABRG2,TFIP11,PRKCQ,WASF3,MEF2B,MRFAP1,IKZF2,CLEC9A,RPL8,NAT9,PGM1,HADH,TMEM88,CLCA1,CNOT6L,GTF2IRD1,CD1E,TRMT11,MRPL40,SMCHD1,B4GALT7,ZSCAN5A,VSTM2A,GSTA4,RHBDD3,PPP5C,RBM42,LDLR,FOXP3,OR7E24,VPS4B,TMEM160,ANAPC11,LACRT,SEPHS1,TOMM7,PCMTD1,RASGEF1C,MAP2K6,CA10,MAD2L1,INPP5E,ASB8,ORMDL1,CDC16,GNB1,GLTP,PYCARD,CUL2,SLC6A8,GHR,MED30,CXCL11,SOCS4,MED9,TREML1,SYCE3,FAM50B,SFTPA1,STX10,TUBB,LSM14B,ZFP64,COIL,CHID1,DISC1,SSR1,AVPI1,NETO2,SMARCD3,RBFOX3,RING1,ZNF596,MCHR1,SFN,TRAPPC10,SF3A1,PSPC1,GNAI3,GPX2,HCLS1,DNAJC1,TRIM46,GLRB,EHHADH,LILRB1,EMP2,OVGP1,STBD1,FAM110B,PAQR9,TRIM63,THAP2,IL4,TIAM1,RUVBL2,IGF2BP1,GOSR1,NCOA5,MMAA,PPIC,ARMC6,CHCHD1,SIKE1,NDN,SNX3,TBC1D5,CLRN1,DBH,USP46,SMAD2,PITPNB,LPAR6,POLR2C,GNAQ,RAD1,DBNDD1,NGRN,GIPC3,NFE2L2,CCDC167,CNOT7,ADRM1,RABIF,CD80,EMX1,PKIB,HNRNPL,IREB2,UBTD2,NMRK1,TAF11,CDC5L,LGI1,SLC35A5,TMEM19,OR2F1,CH25H,HPS6,TCP1,KCNH8,CRMP1,PRR19,ANO3,UBE2N,NGDN,CTRB2,CCL1,PSKH1,FKBP4,STX16,EIF5A2,PI3,SMURF1,DPPA2,PMP2,P2RY10,NKX6-2,GPR22,SLC38A2,HS3ST5,PLAC9,PFDN1,SSR3,LIN7C,SGMS2,ANXA7,NCSTN,TAF2,COL3A1,CBX7,PAK1IP1,VAMP1,GLYATL3,ADRB2,TLR4,GPN2,SLC6A1,MYO1B,QSER1,SLC2A1,GPT,SRSF12,CTTNBP2NL,VDR,IL5,PTGDS,ADRA1A,PEBP1,TNNI1,FGF22,CX3CL1,PSMB2,ADH1A,EAF2,DCK,ITM2A,RPS24,MCM6,NUDT4,DCUN1D1,CYP7A1,DIRAS1,PRRT1,ABCE1,GINS4,SDS,SASH3,TPRA1,TIFA,B2M,SLC52A3,CASP4,SLC15A2,SPOP,DEFB129,TRIM22,CYB5R4,FITM2,MRPL36,NR0B1,AMACR,LYZL4,CST3,SCAMP5,PLEKHO2,ICA1,BCL2L1,YWHAG,ACVR1,VDAC2,DCTN6,MYH1,IFT57,PPP1CC,PAQR8,BAZ1B,PEX26,OR4E2,OR7D4,KCNB1,TNFRSF9,ZNF32,NOP16,DMAP1,LRRC8C,CXCL9,RBPJ,MRPL17,DUSP9,CFDP1,IFNK,SIGMAR1,ATP2B4,EGLN2,KLHL28,EDEM3,TPPP2,RNF152,UQCRC2,MRPL33,LRRTM1,HSP90B1,PSMB11,TCOF1,LRAT,ISOC1,EDDM3B,ZDHHC8,RETN,NKRF,MCPH1,GATAD1,PTGES3,RGS10,ACTN4,ASB1,RPS15,QRSL1,VIPR1,FBXL3,NXT1,SLC35C1,RLN3,ANKRD50,CHMP1A,NEO1,PCCB,HSD17B3,ESAM,MFSD6,POU3F4,MADCAM1,ASRGL1,MPST,PSMC4,RFC5,JRKL,IDH3A,PATE4,TMEM97,MED13L,NSDHL,PI15,HECTD3,FABP12,FGL2,HDAC5,RPL17,UBL4A,SERPINB11,GKAP1,GAPDH,CLIP3,VAC14,SLC25A42,CBLN3,CRYGA,RNF208,GRIA1,YES1,OR4N2,FAM3A,STAC3,MNAT1,FMO3,TNFSF10,CDK5RAP3,NEK9,CLDN6,CAPZA1,GUK1,AGAP2,STX1A,FBXO3,IRF2BP1,CSE1L,UBE2B,ACHE,BOLA1,GGCX,PAQR4,ELOF1,CCAR1,PICK1,NTRK3,TSSK1B,PDIA2,RNF146,SAP30L,FAM76B,SNAP23,ZNF574,EXOSC8,KDM2A,POLD2,KLHDC8A,SUMO1,DCLRE1C,OR10G3,OR2J3,G3BP2,IFT52,ACOX1,FADS2,F7,PIK3R1,TSPAN7,FGF7,MAPRE2,CAV3,EPHA2,PRPF18,IGSF21,CDK2AP2,SRSF1,SLC31A1,DIO3,COX6B1,ITGA2,UCK2,LMBRD1,MRPS35,ATP6V1G2,RAB6B,MMP14,DDI1,COX17,RAB28,ELK1,FAM168B,CYP1B1,MDH1,MRAS,RALYL,MRPL41,KLHL23,HSDL1,ACOT6,IL12B,WDR6,NCALD,ANGPT1,COPS4,KCNK17,ZGLP1,DEFB124,INSIG2,LHB,CBL,ARL6,RAB11B,STX5,CCND3,CSRP1,IRF4,LEMD3,CMTM7,SPATA4,TBC1D16,CA12,SLC7A1,ADRB3,FMOD,SMG5,NUP62,RNF139,PLP2,DUS4L,ABCF1,DYNLL1,LYPLAL1,HSDL2,OPRL1,CCL11,RXFP2,RAB9A,RPAP3,HINT1,TNPO2,THOC6,PYCR1,SLA2,IFNAR1,SDR16C5,MARCKSL1,UFSP1,PTPN5,RNF182,RELL1,SMAD9,TIMM17A,LIPA,CCL24,SNRPD1,JUNB,ALCAM,OAZ3,WBP1L,VCPIP1,SLC39A10,MCCD1,TCEA1,BCAS4,HM13,PGAP3,MB21D2,LCN15,RPL28,HCFC1R1,CACNB2,EDEM2,FIS1,SRP72,SLITRK1,DDIT3,PREP,CDC26,SHC3,PIGC,ARFGAP1,STK38L,MVD,CYP4F22,DYNLRB2,CKS1B,HBP1,SPAG11B,RPL4,SEC14L5,RGL1,SUV39H1,DCTN3,LSM5,IRF2BPL,PRKCB,PABPC5,HCFC2,SLC25A3,RWDD1,COPE,RBM41,IZUMO2,ZNF200,TPST1,AGGF1,LCP1,HNRNPH3,GJB1,GCHFR,CSF2,PCYT1B,KRT8,PRELP,CHCHD2,SKP1,TTLL10,HDAC11,SIGLEC5,ATG16L1,DIRAS3,TP53TG5,PSMB10,CHMP1B,CDK17,ART5,TMEM39A,CDKN2D,GPR37,ESD,ATP6V1D,VWF,CLP1,CLPX,OR5AN1,INA,ATG3,CFTR,VPS39,MYLIP,SUPT4H1,FAM174A,SART3,IFI16,PTPRZ1,PSMD1,BARX2,MPP1,MED27,RANBP10,SRM,ADH1B,SPDYE4,OR4M1,BMPR1B,HS3ST1,TULP3,PCBP4,MLH3,APOBEC3B,FAM193B,BLVRA,RAB32,PITPNA,CRYBA4,CRYZ,FOXC2,RGS1,SDHC,ASB11,FAM83A,NOL12,RHOG,COX7B,CDC42SE1,BGLAP,GAD2,METTL18,RSBN1L,SEC61A1,TTR,ZNF770,TPD52L1,DUSP18,RPS28,UBXN2B,SMUG1,SVIP,CDH7,ASCC1,SLC37A4,CXCL10,FOXD3,LYRM2,FBLN5,MAEA,EID2,ZNF345,KIAA1958,LPCAT3,GPR83,ZCCHC7,PHTF2,PPIL3,DPAGT1,CTSA,HNMT,FA2H,ERRFI1,KCNIP2,SERTAD1,ZHX1,ARF1,ZMYM6,EIF2B2,GNG11,PHF7,MRPS26,HMGB1,CKB,TUBA1B,THAP6,ZBTB26,LRRC14,EMILIN1,PDCD5,PRDX3,BTBD10,ZDHHC24,B3GALT2,PPT1,ARF6,MRPL12,FGR,RCHY1,FAM20C,SPHK2,CXXC1,RPL7A,FIG4,LSM12,DOK5,DCTN4,MAP2K3,SEC22A,RIT2,CACNG3,IFNA13,CBFB,ZC3H14,EFNA5,ASPM,ZC4H2,TADA1,CETN2,PITHD1,SMARCE1,SH3BP4,LEP,UBE3A,OR4B1,PDZK1IP1,OR5K1,PDE6D,S100B,TNIK,LRFN3,IL21,RPL19,HBM,FGF16,POU5F1,MSN,ZNF362,SLITRK5,SAP30,RNASE4,DDIT4L,DICER1,SLC6A7,MAGEB1,SNRNP70,SERINC1,PLEKHF2,GLIPR2,SPCS1,TDP1,MID1IP1,UBE2I,UCP2,TMEM106B,MFAP1,MXD1,LAMTOR2,SLC41A1,PNRC1,ARGLU1,EZH1,RNF7,TECR,MRPL16,KRTAP4-1,MAP3K3,ARL11,FHIT,TMEM176B,BHLHA9,CEBPE,RPL22,B3GALT4,DLG3,RHOU,ACSS2,IFRD1,DEFB1,MAP1LC3B,PDLIM3,PRSS37,ATF3,CTLA4,RBM5,RANBP1,POPDC3,RETSAT,SLC7A11,MET,FZD6,ADIPOR1,PRM1,GAL3ST4,GFM1,SSH3,HOXB8,SEC61G,EMX2,CENPM,PDE6A,IMP4,TRNP1,HELT,TIMMDC1,SERPINB9,UBE2V1,MT1X,RPLP1,SNX11,CYP26A1,GMNN,ISG20,NUDT1,TMEM87A,RALB,FKBP2,PRSS35,UNC45A,TBCEL,CCDC22,KDM1A,NDFIP1,DTL,PSMG2,CEP70,ANKRD46,ABHD2,ARL6IP5,CTDSPL2,SNN,SNRPA1,BIRC5,MFSD3,LDB1,TRAPPC3,CSRNP3,NRGN,GMDS,WNT2,SAP30BP,HAPLN2,EDC3,AANAT,ANKH,YKT6,VPS26B,CAMKV,F2,ARL5B,ESYT1,PSMB4,HERC3,DOK6,SEMA3C,LSM4,HSD17B8,IRF9,DDX39B,CGRRF1,NETO1,CDR2,PTGER2,C9orf72,NAA30,ZMAT3,BRS3,TRAF1,RSL24D1,CLK1,SKAP2,KCTD20,SERPINA3,RASSF4,UQCRC1,NOC4L,CRHR1,AKR1E2,OLA1,HAS3,PRPS1,TSPAN3,BAD,MGST3,ZSWIM7,RPL31,WTAP,SSBP2,PDCD10,GDAP1L1,LRRN4CL,OR6C4,RFX5,TRAPPC2L,TMEM198,NMRAL1,MAT2A,SCG5,PHOSPHO2,TAF9,MEA1,HMGN4,SCHIP1,COX7B2,CMBL,CDKN1B,ZNF655,TEX19,TRIM62,HNRNPAB,GPR78,AHSA1,ZBTB6,PLEKHF1,KCTD16,SLC15A1,SIAH1,STRADB,LRP3,NCK1,USE1,ST8SIA4,TMEM220,TMEM168,CD200,VSTM2L,FBXO31,MAP1B,ZDHHC17,CNOT8,PIGK,PELI1,NEU1,AMELX,VSTM4,PDCD1LG2,RAB1A,GLO1,WDR12,IAH1,MLN,KLF12,ADD2,SOD2,TCTA,PCP2,TMEM231,TEF,ANKRD10,SCN2B,ALG5,DEXI,SUGP1,FMO1,STARD5,ABCC2,ACTR1B,STAP1,HTR2A,SMARCB1,GTF3C4,MMP20,PLCXD3,C1QL2,REG1A,OR4K13,DNM2,TSPYL4,CLRN2,SRD5A3,DCAF16,HIGD1C,TLR5,LCN1,RFC4,HS3ST3A1,TICAM1,GPM6A,OR2D3,PNPO,COTL1,SOX9,KCNG3,CHST10,ITPRIPL2,GAB1,JMJD8,AKT2,APEX1,PRSS1,PSMC5,ECD,CD59,ETFA,APMAP,PRELID1,RIMKLB,AQP3,PSMG4,MRGPRX1,LIPT2,HPCAL1,OR9I1,TRMT5,BCKDK,ZCRB1,MED4,CYB5B,APOC2,NAP1L5,SEMA7A,NACC2,CHRM5,MTA3,DRD3,EMILIN3,NAP1L3,CEACAM5,DIS3L,CA14,CEP57L1,OSBPL8,TACR1,ARHGAP19,THG1L,PDLIM4,GABBR1,ERCC3,TIMM13,RPF2,XBP1,TBC1D1,GPR34,CHTOP,SYPL1,ZNF343,DIO2,EGR1,ZNF436,WBP11,STARD7,ACTL6A,ACP2,GNPAT,FOSL2,SETD3,GPR75,TMEM126A,ARHGAP15,RHOH,ERLIN2,HYAL2,UBE2S,NPBWR1,RPSA,PIK3CG,MAGEA4,STT3A,RRP7A,CCDC126,RBM3,CORO1C,RACGAP1,FXN,SUPT3H,UPRT,SGIP1,MRPS17,MECR,MRPL9,UBE2G2,FEM1B,TRIM26,NUCKS1,IER3,CENPL,KLRC2,TOX4,IFT172,CPNE2,TMBIM1,CYTH4,RAMP3,SLU7,VEZT,FAM3C,PTP4A2,MFAP3L,IRF7,TMEM165,OR8B4,KLHL25,RPE,SULT1B1,MACROD1,CYBRD1,ZNF518B,ADCK1,FAM151B,FAM136A,SLC35E4,PRR13,SLC25A5,OAZ1,WSB1,TOPORS,LYZ,SYNGR3,BRAP,TANK,MPG,MBD3,CDC23,DMPK,ELFN1,OR5M9,HAUS2,GALC,RP9,ELFN2,LRRC8A,CNPY1,SSPN,GNGT2,NKAP,LBX1,RDH11,PIH1D1,KCTD3,ANXA4,IL18BP,RASL12,GALNT2,RRAGB,SNRPE,GRIK1,CMA1,DLGAP4,IGF1,CCR7,SNAP25,RXRG,GORASP2,THUMPD1,TTC9C,PELO,GMPS,ATP8A1,CIAO1,KIF3C,GHRL,VPS18,ZNF581,SUCLG2,PDE7A,DUSP3,SCML1,ZFAND6,TAPT1,MED10,TYMS,NAA16,GJC1,SLC12A2,RUNX1,RPS20,YTHDF2,FAM161A,PDE12,ANKRD6,SRFBP1,ARHGAP12,EIF5B,PFKFB2,ACER3,MREG,DIRAS2,RASSF8,KCTD17,CLEC6A,SSBP4,RBP2,AQP11,TLCD1,FKBP1B,LMO2,EDA2R,LCORL,OR13A1,PSEN1,MAGEC2,TRAPPC6A,MDC1,MTCH2,ITM2B,SP1,CCSER2,MGMT,TADA3,TRAM1,TMEM196,AP1M1,FUNDC1,ECHDC1,UBA52,IMPA2,SPRY1,RPS10,CLDND1,CCDC106,ETNK2,GIN1,TKTL1,RPL18,TBCCD1,TRAF6,VPS72,KRIT1,ROCK2,FUBP3,KCND3,RNF10,FAM133B,GP9,OR51E2,POLE3,KRTAP8-1,APLNR,CYP4V2,SRI,NCAPG2,CNPY3,DTWD2,PSMD3,POLR1D,GPR160,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,OR4D5,TEX261,PTGFR,IL2RB,IP6K1,P2RY4,FBXW4,ST3GAL2,TAS2R7,CD209,STAR,RPL10,TRIP4,PDCL,SUPT5H,SLC25A24,SPINK9,GLCE,SSNA1,GK5,UNC79,THAP1,CD34,FBXL4,CPXM1,PRCP,EID2B,TMEM100,DCTPP1,OR4A47,PRSS8,YPEL4,LDB2,RNASE9,GADD45G,RPA2,TMEM107,PIWIL1,TRAF3IP3,CCDC90B,RGP1,TAB2,SRPK2,ARFGEF1,MED22,NOG,TLR8,PMPCA,TNFSF15,SLC6A2,CD40,AIP,CRY1,SIN3A,CDK7,PLAC1,SCAND1,PSMD7,RGN,FKBPL,CTTNBP2,RAB6A,PYCR2,PDE2A,ZNF428,CDIPT,TNFSF8,OR1M1,RUSC2,CD9,GRPR,GADD45A,IGFBP3,DPEP3,TMEM183A,BTG3,THOC3,PIGA,GLOD4,MX1,BOLL,TGFB2,RBMS2,VPS54,SLC25A27,ZNF622,ATG9A,S100A11,SLC22A6,SPG21,TIA1,DDR1,EXOC3,SAP18,TMEM81,CAP2,PNPLA4,PIAS1,TMEM115,NPC2,NUPR1,PARD6A,LRRC28,TCEA2,HSPD1,EIF1AX,RNASEH2C,HSPA5,GNA11,SERTAD2,HSPB6,MPV17L2,CRYBA1,THAP8,WDR45,NRM,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,NR1I3,PAIP2B,LRP10,TRIM44,TMEM229B,HINFP,CMC1,NUFIP2,GNB3,CCDC3,VAV2,BTG2,ITGB8,CPLX2,PRND,HUWE1,ABHD10,SREK1IP1,FTSJ1,CNTROB,AKR1C1,MRPS11,RAB39B,CSNK1G3,SPEM1,CYP3A43,PDE4B,TTPAL,PMAIP1,CCIN,UBE2L3,EIF3G,MEPCE,LXN,TCEAL8,YIPF3,RPS2,B4GALT4,CAV1,NINJ1,ICOS,BLCAP,RGL2,ITGB5,TRIM34,NDUFC2,TMEM205,TRIM29,CORO6,OIP5,RB1,DPH5,PNMA3,ZBED1,CTXN3,GPR35,DDAH1,HFE,NDUFA1,ALG11,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,NT5DC1,MRPS18C,TRIM36,PROK1,JAK2,PAQR3,CREBZF,PLSCR1,PTP4A3,DCAF12L2,COMMD9,CBLN1,STK3,HSPB2,LILRA2,TNKS2,LY6H,ZNHIT6,PLCB1,GPR17,GPC1,PRSS23,FRZB,FAM149B1,SPP1,TSR2,CHRM3,ARL2BP,ING2,PSMB7,TNFAIP6,FBXW7,DMTF1,PLG,DLK2,CDK12,TXNDC17,ARL4D,LIAS,CITED1,CPLX3,TNNI3K,NPY1R,PSMD10,GCLC,EPHA4,CTU1,KCNJ2,GXYLT2,SLC25A1,HNRNPF,STAMBP,CEND1,EHD4,ZNF511,FAM81A,GRM1,PCGF6,OR4K2,KCNJ10,SHPRH,ADORA1,SLCO3A1,SPATA2,TAF1D,HOMER3,CXCR3,MAGEB10,AASDHPPT,RNF222,REEP4,TM4SF20,CCNA2,GJA1,MAGED2,SURF2,SLC29A1,TM4SF18,OR6X1,TNR,BOK,LSM14A,CAPN2,OR8H3,SLC8A1,ICAM2,ABHD8,OST4,YWHAZ,STARD3NL,CBX3,DR1,GTPBP8,HS2ST1,TRPC1,LYPD6,ELMO2,BCL9,ASPA,GABRA1,PRNP,CAND1,HSD17B10,TMEM89,MIS12,SNX10,CA2,USP6NL,MTDH,SGTA,TPPP3,ZNF263,SSX2IP,SYNPR,BCL6,E4F1,TMED9,GSTCD,DLST,GTF2F1,TMEM185A,NDUFS2,PAIP2,IVNS1ABP,PIK3CA,SNRNP40,FAM83B,JAKMIP2,CDH11,PSMC3,CPT1B,ZBTB39,RBM27,CNN3,ANKMY2,LY96,AP1S2,TMEM47,MAD2L1BP,AKR1B1,ADORA3,APEX2,SF3B1,TAB1,COCH,FEM1C,PIK3AP1,LST1,COX6C,PICALM,XAF1,VTA1,RPIA,CRTC2,GSTM4,TSPAN15,TMEM38B,NPM3,NUDT2,BAX,GH1,PEBP4,ATP1A3,PSD2,TRAPPC13,UBE2E2,FSTL1,RHOBTB3,HGS,POLDIP3,POLR2L,LRRC40,CRISP1,DPH3,ELK3,CD81,MT1E,COX6B2,TMEM170A,RNF133,PRKRA,TSPAN17,ZNF451,PRKCE,WDSUB1,GNRH1,DBR1,TAS2R13,KLHL1,FOXA3,CARTPT,SESTD1,ABHD12,BANF1,PARP2,NF2,RPL26L1,PHF13,CGGBP1,SUMO2,TFB1M,LZTFL1,SNRPB2,KLF3,CCR4,CHRAC1,GGH,TNF,IL17F,PPAT,NUDT9,CYGB,SLC19A3,OLR1,NDST3,FBXO8,PRL,MPPED2,CDC7,MRPS34,IGSF11,CYP2C9,DUSP21,ATAD1,TRIM45,MGAT4A,RBBP8,SGMS1,TIMP4,ACCS,XRCC5,ADTRP,SNRPG,WDR5B,ZDHHC4,CDC20,SEC13,IL2,NBN,TNFAIP8L1,VMAC,TBC1D25,AIPL1,PEX13,NHEJ1,WDR11,FHOD3,SLC35B3,TYROBP,RAB9B,AMT,INPP4A,KCNIP3,ARCN1,EZH2,FGFBP2,STAT6,OR10G7,SNX24,ACADSB,ISG15,WIF1,FN3KRP,DYRK1B,PHYHIP,CTNNA1,RAB2A,WDR44,GPIHBP1,TRAPPC6B,CCNF,VAMP2,BEND5,SNRPA,CMPK1,B4GALT3,PDYN,ZFP1,CRBN,CD226,SACM1L,VPS33A,CAV2,PSRC1,FBXO25,IFI35,CSTF2T,C1QL1,SLC6A11,RAB37,FOLR1,SMN1,AP1AR,PCDH19,RAB5C,PNP,WEE2,STK38,TIMM10,SLC25A4,MRTO4,PTHLH,SMAD3,PPP2R1A,EIF4B,IL6ST,TMEM59,RPL23A,LYNX1,ELMOD1,PLEKHJ1,MLF2,TIMP1,TXNL1,DERL2,ABHD13,ZBTB45,HRH3,RAB1B,INHA,OR5L1,RPAP2,RGS5,ACTL6B,FAM168A,LY6G5C,UBE2D1,SNIP1,SLC4A8,LDHAL6B,CCDC65,SELENOV,HMBS,TDRD7,CD2BP2,RBMX2,NDE1,AMY2B,PPFIA3,OTUD7B,SDHAF2,MED11,CLIC2,ELSPBP1,STX18,ORAI3,SLITRK2,RBFOX2,FOXN2,CDKN1A,GK2,PGM2L1,ROGDI,SLC23A2,GYS1,AKIP1,SOS2,PIWIL2,UQCR11,NGB,GLT8D1,MOV10,TAF5L,PNPLA8,MYEF2,OR14J1,CDH8,CPSF2,PCGF3,GPX5,TRIQK,GDE1,TCEAL7,TMEM14A,LIX1,KLK5,CAB39,DDX4,MRGPRX2,LRRC24,GRIA2,FLYWCH2,TOP3B,TEX12,HIGD2A,B3GNT2,CASP12,TMEM91,ZCCHC9,SLC43A2,BNIP3L,CLDN8,CXCL14,ADAMTS1,TUSC3,RPL6,SPRR1B,GMPPA,CYB561D2,MT2A,PPP1R16A,PXMP2,ATP1A2,DDX42,SLC7A14,KCNH1,CCL17,KIAA1191,GTF2F2,DLG4,PAFAH1B2,OR2H2,CXCR4,HSPA14,CDH13,NPY5R,POLR3B,LCN9,BRD9,PGR,HAND2,RPP25,RBM12,RAN,GLIPR1,SQSTM1,TMEM177,FMO2,BICD2,CREB1,SERPINA5,KIAA0408,NAPG,RNF122,ACP6,SYNJ2BP,TMEM164,APLN,OR4F6,CRYBB3,TAS2R5,TMEM203,PTRH2,FOXS1,ACTR2,NUS1,SRP14,TMEM106C,KRT7,PLEKHA8,MANSC1,GJB2,WDR3,ZNF609,TMCC2,SELENOS,KCNK10,SLCO1A2,PPP1CB,TRAM2,MPV17,FCHO2,CHST1,EHD1,UPF3B,RABL3,ISCA2,ZNF576,GCA,KLHL15,RFXANK,TRAM1L1,PLAGL1,PAPOLB,SESN2,GNPNAT1,GIMAP2,FERMT2,TOMM40L,EIF3J,UTP23,CHI3L1,RNASEL,TNRC6C,SPTBN1,RAB33A,CRYGD,RNF167,FAM107A,PPDPF,TNFSF18,DNAJC8,RAB23,CMAS,SFT2D2,PTGER1,OPHN1,SUMO3,ZNF687,OGG1,CCR3,TMEM50B,JUN,IFNG,CD47,HIRA,S100A8,RHOJ,CBLN4,WWP1,OR2A25,STX6,FANCG,PLA2G15,MAPK1IP1L,TAPBP,HNRNPA2B1,RCBTB1,GGCT,ATP6V1C1,YPEL5,ABRACL,PPID,RFTN2,TPPP,SLC35E1,RB1CC1,CAPZA2,NAA60,CCL8,OAT,RIOK2,MRPS28,POMP,OS9,RPL26,EGLN3,CLDN22,FOS,DYRK2,LHFPL2,ACAP2,SCD5,MAFG,NFKB1,PRKAG1,PAFAH1B3,HNRNPK,TMEM123,DSTYK,AIF1L,CCR2,ZC3H7A,ZBTB5,IPO8,TMSB10,CIDEB,ARMC7,ATAT1,HSP90AB1,POLE4,GPHN,ISG20L2,RER1,FCN2,RGS7BP,CDKN2AIP,SFRP4,SYP,ATG4A,ZNF862,CSRNP1,MRPS23,FUNDC2,CHGA,GBE1,PAPSS2,TCF23,HTR5A,TMX3,DNAJC22,EIF2B3,TOM1,BCL7B,GPR65,SEC61B,TEX30,MYO6,NDUFS8,CYP2C18,ZNF740,F9,PGPEP1,NKX3-1,GCNT3,OPRK1,TOP1,TMEM144,SRRM5,NRSN2,GPR137,SNX17,BCS1L,APOO,CLDN4,LAMB2,SLC13A5,RAB3D,RUVBL1,SDF2L1,CXCL3,GTF2B,NKIRAS1,OAS1,GIT2,ACAT1,TMEM114,ZNF287,TMEM184B,KDM4B,ACBD7,FAM98A,CDC42SE2,RPLP2,TRIM54,OR4Q3,HTR1F,GPAM,LDOC1,PDCD4,PRPF19,CREBBP,RDH10,TGIF2,GREM2,POPDC2,GPX6,CTDSP1,CCNB1,FAM162A,NDUFAF4,AKAP14,CRYBB2,TFCP2,CLDN1,ABHD6,METTL2A,IK,CRTAP,LCP2,UHMK1,ERH,ALKBH5,ADIPOQ,ANKRA2,MAP3K11,GTF2H2,MBL2,TOR2A,PTS,JPH4,AMIGO1,GNG2,EDEM1,METTL14,VAMP5,CSGALNACT1,R3HCC1,SAT1,COL1A2,RMI2,SMU1,SLC35D1,CEP97,ZNF501,IFRD2,ST3GAL5,POR,SLC32A1,FAM163B,PARP11,LRP6,TAS2R40,MRPS21,PYROXD2,STK24,LCA5,NDUFB4,RAC2,PRKAB1,DPEP1,UQCRH,IRF3,CD36,MTHFD2L,ERV3-1,PAX9,STXBP1,KLC2,PCMTD2,STOX2,CSNK1A1L,SOX2,ST3GAL1,DERL1,IL18,DNAJC3,RNASEH1,TMED7,KLK6,FKTN,SLC41A3,SERINC3,TSN,STOML3,STAU1,BRCA1,ABHD4,PCDHB1,TRAF2,RBM7,KCNK13,NPR2,CDK4,CNNM4,NR1I2,DPY30,RGS2,STMN2,NME1,DUSP19,PDHA1,ADPRH,MBD5,NOS1AP,BCL10,KCNMA1,YAF2,ELP3,ACSL4,TRIM24,DTYMK,TGFB3,MRFAP1L1,CIB2,MTRF1,ZNF592,EED,MRPS16,ABHD14B,PROS1,GPX3,TMEM204,B9D2,EWSR1,VMP1,SLC19A2,CBR4,MSMP,HSPA8,EMP3,OSTM1,CHMP2A,CCDC25,FAM219B,TES,LMNB1,BECN1,GMPPB,ADO,CALHM2,RPLP0,UBE2V2,IL10,FUT9,PHYH,RTKN,NTN4,HOXD12,ADIG,ITGA6,CSNK1A1,PELP1,COMMD8,TFE3,IFNA10,MT1M,DEFB114,RNF113A,EFNB1,THTPA,SH3GLB1,PREPL,OLFML3,TSPO2,GOLGA7B,TMSB4X,EIF4E,TRIM5,CALHM3,LHFPL4,COX4I2,CDKN2C,SNAPC3,BLOC1S2,SNCG,IGBP1,AKAP12,SSU72,DDX39A,RAB40AL,BCAP29,ZBTB17,FABP7,CD274,CREB3L4,B3GALNT1,EIF3K,SPECC1L,NAT2,KHDC1,RINT1,BZW2,TSPAN5,OR10G9,RAB3B,CDCA3,SMAP2,KTI12,DNAL1,NDST1,TNFAIP8L2,DEFB116,DHRS3,NKX3-2,MAGOH,TBC1D10C,CCL19,MLF1,GTF2E2,LBH,JAK1,FGF1,INO80C,ABCB1,HBE1,AZGP1,PSME2,AZIN1,TSEN54,SERPINB10,FBXO42,TMEM215,ZNF24,LYG2,MFSD6L,GPBP1L1,MX2,TMEM213,ZCCHC10,SYN3,AAMP,FZD4,MEST,WDR77,MTPN,ATP6V1G1,TMIGD1,DNAJC5,SNAP91,MYH2,SLC7A9,PACSIN3,HEBP1,ALKBH4,PGK1,VRK1,ROPN1B,MMP9,BTF3,S100A6,DYNC1I2,CYP27A1,ZYX,UBAP1,CDC73,LHX2,RS1,KIT,LSM3,AFTPH,OR4D9,JOSD1,P4HA2,SUPT7L,KBTBD2,GSTO2,ATF4,CTNNBIP1,GNG7,GRSF1,RARRES2,KPNA1,CSNK2A1,PIWIL4,IMPACT,CD58,AGER,IDH2,FKBP14,RAB18,ZNF593,ARMCX5,PRPF4,AGK,ANAPC2,FBXO32,SMCP,CCT5,ENPP4,MCOLN1,PSMB5,SORD,SBK2,SLC39A7,CCDC127,RCVRN,PEX3,FAM89B,CRYGB,PPP3CA,KCNJ11,CD200R1,CAMK2N1,HCRT,FGFR1,SHC1,PYGM,OR4K1,CCDC47,TTC4,SCFD1,GHITM,CACNB4,RPL15,TUBG1,CIB3,TACR3,PRMT2,CAMK2G,TMX4,SRP54,BUD31,SLC35E3,SPTAN1,RNASET2,NPY2R,LRP12,FAM199X,PAEP,RABL2B,NIPA2,CLDN11,TRAPPC1,HEY2,PCDHB8,RBM17,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,SPR,ARFIP1,GALNT12,PPARG,ACTA2,SIX5,TRIM21,ARMCX2,RMND5B,RBBP7,SLC25A21,PGS1,NFIL3,ZBTB38,TRIM37,HECW1,PTPN1,HNRNPC,SETD5,FNDC8,COMTD1,APEH,FGD2,DLX1,AKT1,L1CAM,FIBIN,SNX20,WDR38,TLR9,CCNI,ASMT,PPIL4,RAB11A,CDO1,CRABP2,RPS23,DPP10,PRRC2A,SF3B4,IL20RB,DKK3,RND3,CNP,NUDT3,B9D1,LYAR,TOM1L2,PFDN5,EXOC8,UST,MRPL13,EHBP1,MDM2,MGP,SPRN,GSTO1,TMEM156,GALNT1,AK2,SOCS5,PSMA3,CCDC69,MRPL23,GDI2,GFM2,E2F6,ZMPSTE24,EXOSC1,EFCAB7,GPR89A,PDIA6,UBR7,SDR42E1,CD99L2,PRIM2,SNRNP27,TRIM32,KLHDC8B,RNF141,DOK4,ARHGAP1,PLA2G5,KLK9,UGCG,MEAF6,LYPLA1,RPS14,LIG3,SLC17A5,ZNF671,SLC25A31,POLR3H,C1QC,TRIM3,TMUB1,ATP6V0B,TMEM219,EDF1,ZNF207,ID4,ZNF319,SEC14L1,APOBEC3A,ZNF397,XAGE5,SLAMF9,ZMYND19,TAAR1,CCR6,ATPAF2,KIAA0232,CLU,LMO4,GLUL,CNIH4,CDK5R1,NRP1,NCKAP1,FGFR1OP2,GABARAP,PRPSAP1,GRPEL1,TCP11L2,ELMO1,LTBR,GAL3ST1,OR4D11,CASK,IRF1,OR8B8,ING1,STRBP,P2RY1,TRIM23,NAIF1,NHP2,CCT2,CHRM4,UBE2D3,ATP6V0E1,UBE2A,ARMCX1,RMND1,MIOS,PPP1R2,FAM78A,OSM,IL15RA,SLC38A9,MRPL50,MRPL24,ZNF304,SNAPIN,SLC30A5,KLK3,ENY2,RAG1,IMMP2L,MEF2A,HSBP1,DHRS4,SLC35A1,CHDH,GNRH2,CYP39A1,HSD11B1,MYL12A,LRRC69,SWAP70,FAM8A1,ITK,EIF4H,NCR3,TLR3,GPAA1,ADGB,JAKMIP1,SENP5,GALNT4,IDH3B,PYDC2,CYP11B1,CTNNBL1,GRM2,EMC4,SIVA1,GFOD1,SNTA1,SNAPC1,NDUFAF2,GPR37L1,SOST,TCP11L1,SV2B,HPCA,ZNF805,OR2A2,EIF4EBP2,TSSC4,MAK16,ALDH1L1,POLL,NONO,SPRED1,H19,TAPBPL,ETV6,RRAGA,SIRT7,FYTTD1,NOL4,IQSEC1,MMACHC,TRAF7,DUOXA2,MTMR12,RAP2B,ABHD16B,ZBTB42,TNFAIP3,RAB8B,CTNNB1,CYP2D6,SOCS2,INTS12,SFTPD,OAZ2,CLEC12B,SNRPD2,FAM13B,ADCY3,DCAF5,ESR2,CDK6,CWF19L1,ZNF174,USP38,SLPI,USP39,CERK,VPS4A,ENPEP,NAB1,SYNGR1,RTP4,ZMAT5,LSM6,PRKX,FGF13,PROX1,BMPR1A,FAF2,RHCG,SPINK13,ARHGAP21,SCG2,AP3S2,TMEM33,S100PBP,MRPL47,MPHOSPH10,KLF10,RPGRIP1L,OR2W1,CCND1,WFDC13,ACOT13,TMED3,FBXO9,COX7A1,LCN6,OTUD6B,SETD4,DCAF8L2,AP1G2,NDNF,ANP32B,CHST9,CPT2,NFYA,S100A10,FAM200A,STX8,TGFB1I1,DUSP1,TOLLIP,BATF,PWP2,RAB3C,MTAP,CTSK,CACYBP,CETN3,URM1,CTSD,COA4,PGAP2,MRGPRX4,FABP5,AKR1A1,NOP58,SPATS2L,NFE2L1,RBCK1,MRPS25,PPIB,BPGM,CDKN3,CD164,OR52M1,NUP107,SCAMP2,SPEF1,SLC5A6,PRKD3,CYP4F8,NLGN2,DEK,DEGS1,CRYBA2,CCDC42,NPTN,FCAR,POU1F1,CYC1,PTDSS1,ID1,ARMC8,ENTPD4,SLC35A2,KIF2A,BACH1,MIA2,INPPL1,ING5,ZMYND11,SLC7A4,ZNF513,GPR162,APOBEC3C,RNF187,XPO5,SURF4,INTS10,TF,CREB3,RNF103,KIAA0040,EEF2,THRAP3,GJA10,SLC25A32,EFHC1,XPO1,EXOC2,DNAL4,FATE1,ATP2C1,RC3H2,NUDT19,RANGRF,ABCC5,THOC1,GSK3A,PRCC,PFDN6,LDHA,NUBP2,UBXN10,PCDHA5,SLC20A2,IL23A,PSMD6,SLC39A9,FURIN,DHX9,ZSCAN1,OR51S1,EIF4EBP3,WDR37,GLE1,TXNIP,CREBL2,AQP4,CCL25,GNMT,FUT8,WBP2,GTF2A1,UTS2R,NEK7,PHKG1,LASP1,SPOCK1,MOB3C,OSR2,CXXC5,ENDOD1,CIRBP,ANKIB1,EIF2B5,SH3GLB2,GALE,NUDT16,OR6M1,GXYLT1,B4GALT6,KCNA2,HSPB1,LHFPL1,HADHA,LEAP2,DHX16,RAB4A,SOX21,TRA2B,SERPINH1,RPL37A,HSPE1,CLDN14,ZKSCAN1,SIPA1L1,STAMBPL1,PGBD2,SNAI3,PELI3,CDC37L1,KRR1,NLE1,RPRML,MSX2,WNT7A,LEPR,STX17,EIF1AD,NAA11,ISYNA1,NDUFB8,APH1A,CXCL1,FRA10AC1,PDIA3,XPOT,RAP1A,UCKL1,ACAA2,RABAC1,WWP2,FBXO30,TIGD7,CD2,POLR2I,ST13,RASGRP2,LPXN,IL34,DFFA,KCND2,CCL21,NDUFA5,TRMT6,PTCRA,CXCR1,NEDD8,HBB,FGF17,RBM23,TMED1,OCEL1,ADAT1,HEXA,BRI3,OXNAD1,NQO1,IPP,TBCE,SPATA2L,AKR1C2,IGFBP4,LMBR1L,NPVF,OPA3,TAC1,CHRNA7,GAS8,KIF1C,CDKL2,CD3G,BRMS1,PAOX,POLR2D,SNX12,CNTFR,KRT222,SMNDC1,PDP2,NEURL2,NDP,TMEM42,SNX33,MED23,USP13,SDCBP,FGF3,DRG1,ERLEC1,CEP85,SRPRB,MYL12B,GINS3,ENHO,ATP6V1E2,ZHX3,IL7,SRSF4,NECAP2,SH3BGRL,ATXN1L,EXOSC3,PID1,KCTD11,GPR146,OPTN,CLEC7A,APPBP2,ARPC2,FOXJ3,ORMDL3,RAD23B,USP30,UFM1,HAX1,LRRC20,EGR2,OR1F1,RPS3,CHN2,TMEM60,HBEGF,CALU,AIF1,YIF1A,KBTBD13,OR10Q1,CA8,NMBR,LGALS3,MAP4,HHIP,LUC7L3,RAB3A,DDIT4,SMYD3,KPNA2,LCN12,FAM91A1,CTNND1,AUH,TFRC,TTC8,ZNF267,IDE,ZNF177,ZNF652,HSD17B11,PPME1,C1QTNF1,HMGA1,SH2D5,OR1S1,FOXI3,UTP6,MND1,TSPAN11,GGPS1,IPCEF1,PABPC1L,LSM2,TMBIM6,CCT8,DNAJC7,CD83,RPL12,KCTD12,UQCRQ,SOD3,DUSP22,GFOD2,ADAMTS20,YWHAH,FAM187B,MRPL49,GABRB3,MTMR2,PLCL1,ICAM1,AP2A1,APTX,HRH2,SPINT2,ZNF688,RGMB,BCL2A1,TMEM45B,C1D,TFDP2,ZNF22,ACTR3B,MIF,RBM15B,ZNF189,EEF1B2,LRRC8D,ETFB,VIP,NTNG2,FBXO11,RBBP9,SPSB1,HMX1,WNT10B,DGCR6L,GSTM3,SYNDIG1,TSEN34,FTSJ3,SLC25A46,TBC1D17,TMED4,HEXIM2,HSD17B1,TOX,PTRHD1,IRF8,KPNA6,RWDD4,CYB561,BET1,FCER1G,TP53,PPM1M,NFKBIL1,CRELD1,INMT,PRDX6,TAX1BP1,AP2M1,KRTAP3-1,KIN,STX7,SENP8,MGST2,GADD45B,HBA1,OSGIN2,MZT2B,LIMS2,GPC4,NECAP1,PKIA,TRIM35,TRAFD1,PPM1B,PML,GABARAPL2,DNASE1L1,PSMA4,OR10A7,SERTAD3,ZNF250,MT3,EIF1B,GABPB1,SCGB1C1,ARF4,ZNF790,TAX1BP3,RDH12,CALY,TNFSF12,RPS12,CYB5D2,TXN,MAF1,DUSP6,MTHFS,PPIF,SETD7,ZBED3,DAG1,OMG,GPD2,CELA3B,FBXL7,LBR,CYP11B2,PHF21A,COX5A,THNSL1,SLC1A2,TRMT61A,RHBDL3,CAMP,DCAF4L2,RPRD1B,SNRPN,TSPO,LYPLA2,POP7,STYK1,RNF181,ELOVL6,ALOX5AP,TFPT,NUP35,ZNHIT1,MECP2,PRDX4,SLC25A14,RASL11A,TBC1D19,CLSTN3,RGS6,CSTA,OLFM2,ENO1,GNPTG,CHST7,SERPIND1,ORAI2,CRYL1,RPL24,PPP2R5A,VASH1,TLR7,GAPT,PTGES,ACADS,RNF128,EXOC5,SYBU,SERPINB6,NAA15,EBLN2,WDR55,RALA,FTHL17,F11R,G6PD,ADK,OR5B3,BRMS1L,HCST,FBXO34,PAPOLA,DHRS1,CHORDC1,ZBTB16,ANAPC16,TLR1,CAPG,OGDHL,SAR1B,CCR5,RHAG,IL12A,CYTH2,RNF11,SYNGR2,APOC4,TAF7,OR4S2,TLR10,WDR82,ZBTB25,CD28,NAB2,FXYD6,GNL1,ZNF473,SELL,KIAA1143,ATP1B3,DNAJC2,GNB1L,PPY,CRYAB,ROMO1,LAMP3,CHPF,REEP6,MATR3,CNOT6,PPP1R3C,CRADD,KCNAB1,AGTRAP,SEMA5A,MCMBP,APBB3,S1PR4,FAM169A,TNFAIP1,TMEM11,CFL1,KLHL3,BRIX1,IRGQ,RPS26,RNF40,DDX1,KDELR2,DAP,DPM2,RNASE6,TP53I3,SLCO1B3,GOSR2,FGF23,CYP2R1,SLC25A39,CD14,PRR5L,G6PC3,RANBP6,CCL27,ZC3H11A,TMX2,HTR1A,METAP1,SFRP1,ELF1,WSCD1,CD86,PNMA5,MANBAL,PSENEN,SLC2A8,OXCT1,ENO2,ZNF704,PTPMT1,KBTBD6,EXD2,FARSA,UBE2H,VPS26A,CMTM6,EEF1E1,SMG8,TMEM50A,MYC,TAS2R39,LILRB4,CD40LG,FEM1A,SHISA2,KCTD10,RAB35,MAB21L1,ASF1A,PPP1R8,MKLN1,CCL28,MYL6,GEMIN8,RPS9,TIRAP,SEC23A,TUSC2,OR5V1,PSMG3,GPR173,TOP2B,CALML5,VAPB,PNMA1,SP2,HEBP2,SLC6A3,CASC3,CNKSR3,TCF21,AKAP1,CLEC1A,DNAJC24,PARM1,PSMA6,PCSK9,KBTBD3,AGR2,CACNB3,PCBD1,TTC23,NLGN1,TMEM174,MORF4L1,CPSF4,LCN8,AGA,CD63,ACO2,VPS16,CLN8,SLC25A26,SYK,TNFAIP8L3,CDC42,SLC48A1,DUSP10,BACE1,SLC38A1,PIWIL3,IL2RG,FTH1,SNX1,PSEN2,SLC35F1,CCM2,ALB,KLHL26,BET1L,WRAP53,MAP3K21,MMD,GAS2,UCHL3,TRAPPC4,EEF1A1,PAAF1,TFPI,PRKCA,BRD3,SURF6,FAR2,TMEM108,DVL2,TESK1,TTC33,OR2AT4,C2CD4C,RPL39,ADM2,IZUMO4,ALDH1A3,AHCYL1,GINM1,NPTX1,CLIC4,MAGED4B,COX11,HNRNPH2,HMOX2,EXTL2,RCCD1,SLC20A1,ALPL,LAP3,ADIPOR2,C2CD2,EFHD1,SAMM50,KCNJ8,ENC1,PYGB,TRIM6,HOMER1,PSMB9,PDE8A,FOXP1,SLC4A10,PHACTR1,CRYM,SAMHD1,TPH2,SPRYD4,KCNS1,FKBP1A,SRXN1,P2RY12,DNAJC30,EHD3,ST3GAL4,MRPS18B,ZMAT2,NT5C2,DOLK,RPL9,TST,DGCR8,RNF5,API5,LRRTM2,ELOVL4,PAK6,CHMP2B,CSNK1E,SKA1,GRB10,PIGY,ERVFRD-1,AKT3,MAN1A2,POLD4,CCDC92,RBP5,EIF3D,DNAJC4,OR5A2,CPLX1,PLSCR3,ARMCX3,CUL3,COX16,FAS,ATF1,ABCB9,MAD2L2,UBTD1,TMPO,POLR3GL,COX6A2,RBBP4,TXNRD2,DNAJB4,C2CD2L,RAD21,RAP1B,AKAP17A,SNX14,AIFM1,POLR2G,COQ10B,ACTR1A,FITM1,LAT2,CARHSP1,TIMM8A,NPC1L1,KLHL9,SDC2,ACVR1B,FAH,CAMSAP2,CTDSP2,RPL10A,ANAPC4,GDPD3,ARPP19,LRRC4B,TOMM40,GREM1,COX4I1,FABP4,MPHOSPH6,MAP1S,BHLHE40,PI16,BPIFB4,MRPL53,NLRP2,HDAC3,RPL29,GLRA2,PEA15,RNF8,AKAP8L,CEP41,EP300,ADAMTS10,MRPL20,COPS5,STAT5A,EIF4A2,OTX2,MAGEH1,PRDM4,FEZ1,FPGT,LRRC3B,PLCB2,MAP2K1,APOBEC3F,HSD17B6,TMEM167B,PTPN4,CHRNB2,GPX7,RIT1,OR10P1,SOSTDC1,MORC2,SSR2,ELOVL1,TPM3,SNRPB,EFNA3,AR,IFI6,PPM1K,OR8B12,GSTP1,LLPH,CCL2,TMEM45A,CGB8,RNASE1,NLRP9,FAM43A,LAMP2,TMEM237,TNFRSF1B,CDNF,TGFBR2,CEBPG,USP3,CAPN1,CYP2C8,METTL22,ASZ1,SEMA4C,SLC2A3,FBXO7,RABGGTB,SPIN3,ANP32A,CLLU1,RPL23,CTTN,STOM,HP,VAMP7,CLEC18A,SMAD1,AQP2,SPC24,CHST13,ZNRF1,KLHL24,FKBP8,GABPA,PPP2CB,RCL1,SF3B5,PPAN,IL2RA,TMEM70,MPDU1,VAMP8,TTL,PMM2,PRMT6,PRSS12,PPP3R2,TIMP3,POLR1B,CER1,CHCHD6,SIAH2,UPK1A,HOXC4,EPS8,RFXAP,MTM1,BIRC2,FCGR2B,IFIH1,NUDT7,RAB19,UMPS,CD1C,SS18,MRPL22,CDCA7L,CEP19,CHMP4C,PDAP1,SOX14,SLCO2B1,CX3CR1,IGF1R,UBP1,MAVS,KLHL22,NR2E1,DROSHA,ORC6,FLOT1,THOC2,STARD4,FAM177A1,DCTD,SCNM1,MCM4,CLEC2B,SEPHS2,CBR3,JKAMP,ADD1,LANCL2,APOBEC3H,GLRX2,PRKACB,ASB7,VDAC1,CLPB,FEN1,KLF1,ODAM,CNOT2,OTOS,CRHBP,ZNF326,MYBL2,PLEKHO1,GSTM5,ERAS,FCGR1A,DNAJC19,VGLL4,SCML2,CLDN12,PKP4,GPR176,ELF5,CHKB,CCNY,TAF10,PRDX1,FAM53B,NFKBIA,NPW,TUSC1,PREB,ATG7,TRIM68,LRRC8B,ETF1,KLF4,COPS7B,DENND2D,OR10A6,OR4D2,RNF34,ACBD6,RFC3,SLC7A8,FBXO22,GPM6B,REG1B,HLF,ACP5,SERPINC1,EGFL7,TMEM59L,ATP6V1A,GTDC1,UBIAD1,LRRC61,TSNAX,POLR2B,UBE2W,PARL,DHRS13,TM4SF19,CRAT,NOTCH2,NAPA,PTPN11,SOBP,GNPDA2,TMOD2,CCR1,REN,SOD1,ATXN10,TBC1D13,ASTN1,NCBP2,SMPD2,DTWD1,AVL9,DECR2,TP53INP1,IQCK,FAF1,VEGFA,DDRGK1,RPL32,PSMA1,DRGX,SHOC2,HDHD3,HARBI1,TMED5,PFDN2,TCEAL1,LTB,USP16,CLCN6,AK3,HMGCS1,SLC25A12,CLDN9,SLC35F2,SYNCRIP,TRMT112,VGLL2,DIO1,SLC16A10,PTH2,MTF1,RNF148,PRICKLE2,MSTN,RPL27,PPP1R1A,SPSB3,TOR1B,KANSL3,FAM83C,UGT1A1,LTA,MRPS9,ABCG2,IFNB1,UBL5,BTN2A2,CSH1,POLB,MNS1,UBASH3B,POLA2,SEMG2,CCNH,KIAA0513,SERPINB1,UBLCP1,GSTA1,SRSF2,TRAK2,AVPR1B,ST7,TEX264,SNRK,NKIRAS2,FAM181B,ACVR1C,RBM38,IL1R2,TMEM41A,KLF9,PIP4K2C,STUB1,BST2,PPP2R2C,SPON1,STK4,SLC22A17,TNKS,ST8SIA5,CYP1A1,PLS3,ZNF821,HINT3,CTXN2,VRTN,SLC25A10,RPRD1A,GTF2H5,DDX50,TMEM147,USP8,COX8A,LGALS8,COX20,GPR171,DHX38,PTK7,PGRMC1,METTL15,NEUROD2,BABAM1,RPL27A,NUDT12,CBLN2,TYW5,SNAP29,JAGN1,NDUFAB1,HTRA2,THBD,OR4D6,BCL7C,IL1A,CINP,FBXW11,PPFIA2,CNDP2,FBXO44,ARPC3,DKC1,HR,LRRC3,DNTTIP1,AGPAT5,PLD3,CREG2,PCYOX1L,CTSC,NDUFS6,TMEM126B,PDE1B,UBE2K,PIK3R2,DDX23,PCNA,SPRED2,OPRM1,CDAN1,FZD3,CD247,RHOBTB1,IKZF5,CHST2,HNRNPA0,NXT2,GLRX5,RTN4,GNAZ,SIAE,GAMT,ISX,TOMM6,DNAJB9,ARG2,RNF144B,PABPC1,GNG12,NTRK2,TWIST2,APOBEC3G,CNRIP1,FKRP,LPAR2,USP15,ELMOD2,OR10A4,MME,METAP2,ZFAND2A,SEC22C,SMG9,MUL1,GNG10,TMA7,CTXN1,MAPRE1,NRN1,RORB,CKS2,ABHD5,CXCL13,EPHX1,MOXD1,CCDC160,RPA3,SIT1,FDFT1,NEGR1,GFPT1,SDHB,ATG4C,SNRNP48,FRRS1,CENPW,RWDD3,TXNDC12,UAP1,THAP7,PTAR1,MGAT5B,CRLF3,UCN,INO80E,DEPDC1B,PTEN,RLIM,ADAM21,CLDN3,SHISAL2B,SCGB1D1,NLRP3,ILDR1,CCS,RASD1,OLFM3,SCG3,BMPR2,COMMD3,RND2,PPP1R1B,IER2,CHPF2,NDUFAF3,CFC1,ZMYM3,CRIP1,PSMB1,HERC4,DKK1,NR2F6,CNTN2,ASNSD1,RRM1,RBM22,KRAS,RPS16,KDELR1,TOM1L1,BAG3,ZNF365,ORC5,ILF2,OXSR1,OXTR,KCNC1,SLC38A7,PGGT1B,CHIC2,CHCHD4,FBXL19,LAPTM4A,MRGPRX3,SUFU,MTA2,CCDC86,RAPGEF5,ELOVL7,DBT,TPD52,DSTN,DAPK3,RPS27A,PCDHB13,SLC16A1,NUF2,HINT2,TMEM101,OR13C8,MRPL18,FGFBP1,MFSD5,PSORS1C2,POP5,CHAC2,G3BP1,METTL21A,GANAB,RPS6KA4,TSPAN18,XCL1,BBS5,ZNF664,MAT2B,MLC1,OCRL,DDX46,PDHB,CCDC134,SLC30A7,TCF19,SLC6A6,GPX1,RELL2,TRIM15,GRAP2,RAB27A,RPS7,NPPC,PSMD4,DHX15,OVOL1,RHEB,FBXL14,SH2D1A,PPP2R5E,SLC11A2,UBB,NPSR1,LMAN1,HSPA13,ANKRD34B,LSM10,LRRTM3,DAAM1,SCLT1,MRPL11,PMP22,SERPINA1,OR2Y1,STX11,LARP4B,TMEM179B,BFAR,TOMM22,REEP3,ST6GAL1,CSGALNACT2,CSTF3,RPL7L1,HENMT1,PRR3,IL22,PCDH17,EPCAM,SAV1,STAT2,TAGLN3,SRSF7,UBA3,CBLL1,TOR3A,GLRX,TMEM170B,TMEM117,MRPL34,NDUFB6,CYP21A2,GNAO1,NCDN,FASTKD5,CST11,SNX22,SFXN2,GNPDA1,KCNJ3,COMMD6,B3GALT1,AFAP1L2,TMEM30A,UBL3,IMP3,IRAK4 |
| 2.918e-17 | -38.07 | protein transport | biological process | GO:0015031 | 1086 | 446 | 18204 | 5365 |
COMT,ARHGAP1,TRAM1,SCAMP5,HSPA8,SLC15A1,LARGE1,CHMP1B,SNX20,TMED7,NETO1,TOMM70,RPAIN,NUP42,ARF4,AZGP1,GNPTG,TP53,SVBP,STK4,ARF1,KIF3B,EHD1,VPS4A,GLE1,CD3G,RABIF,UFD1,TMED5,GABARAPL2,MLC1,CHMP5,CETN3,STX12,SCFD1,PPARG,CHMP4C,ARCN1,SLC15A2,DESI1,ANKRD50,LIN7C,BET1,RPL23,RAB39B,YIF1A,CCDC22,SAMM50,SRP54,KPNA2,SNX2,AP1AR,AGAP1,CHCHD4,RAB3C,CEP41,IPO8,RAB32,RANGRF,SEC22A,RAB6A,STX1A,CDK5,GOLPH3L,RAB11B,ARL4D,VPS28,CTDSPL2,SNX22,RHOB,APPBP2,GRPEL2,RANBP6,PPT1,RAF1,RAB2A,SEC13,ERLEC1,RAB11A,ING1,SNX14,RAB6B,VAMP7,RAB9B,TBC1D17,RP2,SEC61A1,LMAN1,TBC1D5,EXOC3,EXOC8,EXOC5,ARF6,PEX3,TBC1D13,SPRN,PLEKHA8,RAB37,VAMP2,TOMM20,TIMM23,CDKN1A,ATG3,HSP90B1,RAB31,CTTN,NUP35,TRIM23,STRADB,GPR89A,RAB18,REP15,HNF1B,NXT1,YWHAH,RAB9A,SCG2,UNC119B,SYNDIG1,STX8,BTF3,HSP90AA1,SNAP25,STK3,GDI2,MTCH2,CNIH4,FCHSD2,DNAJC19,PREPL,ABCB9,SEC61G,RAB4A,ARFIP1,TOMM40,GOSR2,HSPB1,GOSR1,ZFAND6,SLU7,FAF2,HSPA5,TNPO3,IFT22,TRAM2,SNX3,SMAD2,CCDC186,VAMP5,PSEN1,ARL6IP5,EGR2,MTM1,AP2A1,MCOLN1,CAV1,NECAP2,TNKS,AGAP2,RAB1A,BLOC1S3,FKBP1B,PLEKHF2,AP2M1,COG1,VTI1B,TOMM22,TMEM115,RAB3B,TRIM37,CMTM6,RABL3,PEX13,NAPG,RAB1B,VAMP8,EIF2D,SNX33,TIMM10,AP5S1,VPS4B,PPY,TVP23B,TOM1L2,LCA5,CHP1,RAB29,SEC22B,JAGN1,VTA1,CBL,BAG3,ARL5B,AP5M1,ATP1B1,NAPA,CBLN1,POLA2,BECN1,RAB3A,RAB13,CSE1L,COPZ2,HPS6,TTC8,XPO5,OS9,ACTN4,PRKCB,AFTPH,RAB28,HGS,JAKMIP1,WDR11,VIPAS39,RABL2B,PPID,OLFM2,DAG1,ZMAT3,HIKESHI,PHB2,PARP11,RAB40AL,LEP,SQSTM1,STX18,SEC23A,ARFGAP3,STX5,PAFAH1B1,RAB22A,SNX10,NUP107,SURF4,ARL4A,NEO1,GPIHBP1,RAB8B,STX10,ZFAND2B,PHAX,TOM1,AGK,SNX1,PIK3R2,MTX2,SNCG,PIK3R1,RAN,EHBP1,CPLX1,TRIM3,MIR301B,AP3S2,TOMM7,STX17,TIMM21,BICD2,TMED3,BET1L,SNX11,SEC62,SNX17,AP2S1,GOLGA7,TOMM6,CTSA,KDELR1,SEC61A2,SNX24,SYS1,SYK,RINT1,CLU,RAB14,ARFGEF1,SCG5,DERL2,LIN7B,TESC,HDAC6,ZDHHC17,STX16,SELENOT,GRPEL1,TMED9,STX11,UBAP1,ATG16L1,ATG4A,SPTBN1,CD63,XPO1,RILPL2,VMP1,NUP37,NXT2,RAB33B,TFRC,TIMM13,SEC63,CLTRN,YKT6,STX6,CD2AP,SNAP23,DNLZ,USE1,NDP,VPS16,RAB5A,VAMP3,PICK1,VPS54,TRMT10B,RAB35,YIPF5,VIP,RAB19,SRPRA,CBLN4,TRAM1L1,ARL6,NECAP1,EXOC2,EHD3,NUP62,PML,DRD1,KCNJ8,TIMM8B,VPS33A,TNPO2,VPS26B,TMED1,AP1G2,CPLX3,HSPD1,AP1S2,CLIP3,SNAP29,MIA2,MIR130B,SNAP91,GPM6B,BBS5,ACVR1C,DNAJC27,MACIR,MYO6,RAB23,COPE,ARL11,KPNA1,MX2,DUOXA2,TOM1L1,AHCYL1,LAMP2,ERP29,SEC22C,TRAF3IP2,CHMP1A,CETN2,FAM53C,SMURF1,ATG7,DNM2,GUK1,MCL1,EXOC1,SFN,HM13,PPP1R10,SFT2D2,TIMM17A,CACNG3,CHMP2A,XPOT,TXNIP,TIMM29,EDNRA,PEX5L,SAR1B,CHMP2B,CD36,SNAPIN,OPTN,VPS18,SCAMP2,ARFGAP1,PEX26,FAM53B,PPP3CA,LMNA,AKT1,AIFM1,TMED4,VPS26A,GABARAP,SELENOS,FKRP,VPS39,ENY2,RAB5C,AP1M1,NFKBIA,ROMO1,SNX5,CALR,NSG1,CAMK2G,SNX18,VPS26C,RAB3D,SLC1A1,KDELR2,IFT25,CCHCR1,SNX12,FHIP1B,XBP1,CYB5R4,TIMM8A,SEC61B,NUP153,NUP50,ARRDC3,ATG4C,SYNRG,STXBP1,TSG101,STX7,VLDLR,PRKCE,RAMP3,TOMM40L,FAM91A1,KPNA6,SYVN1,TUBA1A,RAB27A,SLC4A8,BCAP29,DERL1 |
| 2.950e-17 | -38.06 | RBX1 (ring-box 1) | protein interactions | 9978 | 540 | 242 | 19454 | 5460 |
CUL3,CUL2,GLT8D2,SAMHD1,LMNB1,RHOB,YWHAZ,RPS5,NLRP3,RIT1,DIO2,RAN,IP6K1,PRDX2,TUBB,ACTB,TAB1,RPL19,DET1,RNF7,MYL6,SLC25A3,PMAIP1,YTHDF1,ASB3,CCND3,SKP1,FBXO30,HMGA1,PSMD3,FEM1B,UBE2D1,HAX1,HNRNPD,DCAF11,CDKN1B,RPL8,KLHL7,CBFB,FBXO32,RPLP1,HP1BP3,RPLP2,COPS2,COPS7B,RPL7,SNX18,KCTD10,SRSF10,CGGBP1,DHX15,OS9,CSNK1E,RPL29,GFPT1,DCUN1D3,EZH2,RBPJ,SNRPE,RNF126,HSPD1,SLC25A5,HNRNPA2B1,ARB2A,BAG2,KCTD17,COPS4,FBXO7,TUFM,NONO,RHOBTB3,NEURL2,DEDD,CCNF,ENO1,TUBA1B,GANAB,TRIM27,RPL13A,ARMC6,UBE2L3,RPL22,CCND1,UBE2F,RARS1,HELLS,FBXW7,RPL4,FBXO9,MBD3,KLHL9,SUV39H1,CRBN,RPL12,AIFM1,SMAD3,LDLR,DCUN1D1,CGAS,MTA3,DDX39A,EEF1A1,RPL15,ENC1,ITGB8,ILF2,SLC25A10,RPL23A,HINT1,KLHL15,PC,SERTAD1,FBXO25,MDC1,H2AC6,RIGI,COPS7A,HNRNPC,CXCL1,MLF2,PCCB,CKB,CCT2,FTSJ3,H2AZ2,CHTOP,H1-10,FBXW11,OSGEP,COP1,H1-1,FBXL14,LMBR1L,STAT2,MATR3,FBXO22,PSMD6,POLR2B,FRZB,CBX5,KBTBD6,RPL10,KLHL3,RPL27A,FBXO42,HSPA8,DDX5,HNRNPA0,UBE2D3,GSTM3,RPL6,UBE2E2,CENPW,ASB7,HSPB1,FBXO31,SERPINC1,WDR82,HNRNPL,HSP90AB1,SOX2,H1-3,EEF2,RPS7,CSRNP3,TUBB4B,PLS3,CRELD1,MTA2,GHR,RPS23,MOB3C,DCUN1D5,RPL18,FBXO3,PABPC1,TOP2B,CCT8,RUVBL2,TRIM21,FBXO11,HNRNPF,PSMA2,KRAS,H1-6,RPL28,HNRNPDL,MAGEC2,MAT2A,RPL7A,RPS17,FBXO44,SPOP,UBE2E3,DTL,ATP1A1,CALU,UQCRC2,RPS3,PSMA6,MOB4,MACROH2A1,GMDS,UBE2W,UBE2M,ACACA,RAG1,PML,BANF1,ELOF1,RNF113A,TNFAIP1,HDAC3,EIF4E,HSPA5,COPS5,ELOC,RPL24,RPL10A,MAP4,SSBP1,RPL32,UBE2G2,ALYREF,KCTD3,CAND1,SHPRH,LRRC14,STX6,TP53,H2AX,CBX3,SESN2,KLHL24,RPL3,DHX9,NEDD8,KPNA2,CSE1L,HNRNPK,PHF1,RPL17 |
| 2.958e-17 | -38.06 | QARS1 (glutaminyl-tRNA synthetase 1) | protein interactions | 5859 | 403 | 192 | 19454 | 5460 |
SKIC8,NAB2,MIR1-1,SAV1,HNRNPA1,CCAR2,TRIM35,STK3,DHX15,PHB1,MIR7-2,SPRED2,DNM2,MIR141,EZH2,GTPBP1,RNF126,RAF1,EMC8,HNRNPA2B1,GADD45A,SRSF7,BRCA1,FAM83A,RIT1,MIR363,PIK3R3,CUL3,CUL2,MIR98,IRF1,TOMM40,LAMTOR3,DYNLL1,RPL19,PRRC2A,BTG3,MIRLET7D,RAN,TRMT6,ANXA7,SPDYE4,CDKN1A,PRDX3,G3BP2,MIR106A,RNF11,MIR34A,MOV10,HDAC6,EIF2B2,MRPS23,G6PD,FAM118B,MIR106B,MIR25,SHLD1,MIR17,SRP72,COMTD1,RPL15,MAP1LC3B,MIR200C,MIR15A,HUWE1,SMN1,RAB1A,RPL23A,MAPRE1,MCCD1,USP14,VIRMA,CCNF,OPTN,TRIM27,HSP90B1,GRM2,METTL14,RARS1,PDCL,RPLP0,RPL26L1,EEF1E1,FAM161A,RBFOX2,MIR1-2,FBXW7,MIR7-3,IRF7,TTR,MIR205,RPA3,MIR34C,MIRLET7I,MIR31,AGR2,DRG1,MIR140,DDX1,SMAD9,MIR221,WWP2,MIR143,SYNJ2BP,IFI16,GSTM3,DDRGK1,MIR29C,MIR9-1,EIF2S1,HMG20A,MIR214,MOB3C,TOP3B,SOX2,TRAF2,MIR222,ISG15,MIR155,KRAS,CCT8,PABPC1,MIR9-2,RTCB,MIR206,PICK1,ATG3,MYC,FBXO22,PSMD6,RPL10,APEX1,USP38,LMBR1L,SF3B4,MIRLET7B,PPT1,PIH1D1,RPL27A,STAU1,UFL1,B9D2,RFC4,RAB5A,EP300,HSPA8,HDAC5,H2AC4,MAP4,DPP4,KARS1,EDC3,GAPDH,MIRLET7G,RPS16,FZR1,TMPO,IK,DISC1,FURIN,CDK4,KBTBD4,ESS2,H2AX,MIR16-2,MIRLET7C,MIR200A,MAP1B,DHX9,MIR9-3,MRPS18B,ERO1A,ATP1B3,UBE2H,RPL7A,MAT2A,PSPC1,EIF2B3,RPA2,SDCBP,MIR7-1,MIR21,CAPN1,MIR34B,CFTR,MARS1,MIR107,HSPA5,BAP1,MIR10B,RPL27,RNF113A |
| 3.289e-17 | -37.95 | endomembrane system | cellular component | GO:0012505 | 4764 | 1614 | 19108 | 5553 |
TMEM165,NTF4,TMEM209,SEC13,MAN1A2,KCNH1,HDAC3,LMBR1L,RAB27A,GPAA1,TBC1D10C,TLR3,TRAK2,TRAF3IP3,CERS2,PDIA2,PSMD7,SDF2L1,XBP1,TICAM1,SLC1A1,MAD2L1,CYTH4,ATP6V1G1,SEC23A,SLC39A13,JAK2,CD1A,STX17,SSPN,DIO1,PLD3,SRC,TFG,MMD,CNIH1,STX12,TM4SF20,SRSF1,TLR9,NPTX1,TRAPPC3L,RND3,XPO1,HM13,DHRS4,LYPLA1,DES,AVL9,SLC35A5,PSMD12,IGFBP3,ARFGEF1,TMEM50A,TMEM170A,BRAP,RAB5C,ENO1,SYN3,RAB35,FIS1,CDIP1,TMEM117,NTRK2,RHOBTB3,SEC61A2,DYNC1I1,PEDS1,GGH,CMA1,WDR77,SLC35D1,RPL27A,SRGN,RPS12,CD1E,B3GALT4,YES1,TMX2,RPS24,TRIM5,CRTAP,PLAC8,PSMB7,OCIAD2,CAPN1,TFPI,AQP11,VPS28,VCPIP1,KIF1C,TOM1L1,PHETA2,SCYL2,CD47,CLIP3,NAA60,VWF,TNFRSF1B,EEF1G,LAMB2,ABCB9,SFTPC,FCAR,AGPAT5,PDE4B,STX11,GNAI3,ERLIN1,CXCR4,LMNA,CDC42EP3,AP2A1,RNASEK,FAM169A,ATG101,LPCAT3,KCNIP3,CD4,DNAJB9,ERLIN2,IFT22,CYB561,MEST,ITGAV,TMEM59,GPR15,SLC2A1,FAM20C,STMN2,COPE,CD1C,ATP6V1E2,PLEKHA8,PREPL,RIC3,TLR4,STK24,SLC37A4,FAM156A,CXCR1,ITM2A,TNIK,CHST1,TRAPPC14,ATP6V1A,CRHBP,PPFIA3,PDAP1,PLG,SLC38A9,CD14,ARF4,GLUL,PRKCA,CYP2R1,ALOX5AP,GSTM2,MGAT4B,SIGMAR1,SNAP25,WDR11,LRP3,FKBP1B,DLG4,DAG1,SPRY1,MATR3,TMBIM6,CAMLG,CHMP1A,FIG4,DLG1,PYGB,NAPG,RAB39B,CFAP119,INPP5K,FIBIN,RPL10,RPS23,TOLLIP,ACO1,MTDH,SRPRA,KCNA2,CHGA,SNAP29,SYNE4,BPNT2,RPL18,ATP2C1,DKK1,MAGED2,CRABP2,DNASE1L1,FMO3,FKRP,SLC35C1,IL1B,ZFAND2B,P3H1,RPL24,CDC42EP2,SLC11A2,NBN,BCL2L1,CHRDL1,SCG2,IL15,TEX261,BMPR2,BCL9,SPACDR,STX6,TRIM68,ATL1,SQSTM1,DEGS1,PDE2A,ATP6V0B,ST3GAL1,RAP2B,CCNI,TNPO3,PLAAT3,PLEKHF2,KIT,TRAPPC2L,CHIC2,RP2,MOB4,SERPINB9,C2CD2L,PRSS23,TMEM147,PLSCR1,SERPINC1,PHTF2,VPS18,UFD1,JAKMIP2,RAB1B,KLHL12,IL12B,ATP8A1,UBXN10,KCNJ11,MS4A7,RNF133,CPNE1,ATG16L1,PCSK9,TLCD3B,HEXA,PARP11,RAB3A,SNX11,AGAP2,PAK5,RABL2B,ATG7,MANSC1,ZDHHC15,CD2AP,GJA1,SLC35A1,NRSN1,ADIPOQ,PREB,TRAM1L1,TMX4,TMEM115,LDAH,SCFD1,GRAP2,ACAP2,VRK1,CTTN,RAP2C,TM9SF4,ENPP4,ACTN4,CLU,CD59,SYP,AP5M1,AGA,JUP,AHCYL1,ORMDL3,FOLR1,NSDHL,ELAVL4,SEPHS1,DSN1,MNS1,NDUFB8,RPS3,ADRB2,ERG28,NLGN1,PTP4A3,TSPO,SRXN1,FCGR2A,VPS54,SLC39A9,UBA52,AP1G2,CHST13,ABCC5,SMPD2,CYP26A1,DYNLL1,ARFGAP3,TASL,MARCHF4,ADRA1A,ACTR1B,ARL5B,EHD4,SLC35B4,RAB9B,EDEM2,HS3ST1,PTPN1,TPD52,FKBP8,SNX5,CYP21A2,SLC48A1,PGS1,TRAF2,EHD3,KDELR1,YIPF4,HCRT,NSFL1C,SDC4,RAB33A,ARL6IP6,SLC52A3,DISC1,PIGA,NT5C3A,SH3GLB1,NOSIP,SEC22B,IL2RG,PROS1,PRSS37,SERPINA1,ABHD4,RAP1A,ARFIP1,NPPC,NHERF1,BCAP29,CYRIB,SYNGR2,PIP4K2C,NUP107,SELENOK,CYP1B1,FCHO2,BLOC1S3,RAB18,NCDN,VTI1B,ACER3,ARMC8,SLC35E3,GABRA2,ITM2B,EPHA4,VDAC2,CYB5R3,LRAT,RNF121,CLEC18A,HSP90B1,IFIT2,TOR1AIP2,PSEN1,GABARAPL2,MMP14,PSMA5,ABHD6,STX7,GH1,GRIA2,B4GALT1,CYSTM1,CLSTN3,TRAPPC6A,HGS,CD164,NFE2L1,CD46,RNF34,SOST,FGD2,ERP29,RAB33B,TAFA1,OS9,HS2ST1,PGAP3,INSIG2,SSR1,TXNRD3,SLC30A7,TSPO2,CDC42EP4,NUP42,RNF5,RETN,LACRT,CST3,SLC35G2,AKT2,DPAGT1,ELOVL1,PTGES,NUP37,BGLAP,RPS28,B4GALT3,RPL6,ZFAND2A,TSG101,PGAP2,GAL3ST4,FLOT1,ALG5,CDK4,SYNPR,PLEKHJ1,COG1,TMEM176B,NEO1,FCHSD2,DOLK,ZMPSTE24,MOSMO,GOLPH3L,COPZ2,PLEKHO2,GOLGA7,FEZ1,HSPA8,NFKB1,GLT8D2,SYNGR4,PAQR8,SPHK2,CSNK2B,RANBP1,GPR37,CD38,SPPL3,TTR,BMP1,FAF1,OPTN,ATP6AP2,NF2,TPST1,B3GALT1,WDR3,NLRP2,SPG21,GLIPR2,SERPINH1,SELENOT,TSPAN15,CALR,CSE1L,CUL3,CD1B,PRICKLE2,CFTR,CYB5A,EDEM1,SLC30A5,IL6,RPLP0,PIP4P1,CYP7A1,FAM3C,EMC9,RRAS2,CDIPT,CAMP,DIO3,CAMSAP2,SLC32A1,NRP1,SPP1,APOO,SYNRG,NOTCH2,CD247,FGF7,PSMD3,APEX1,SMAD3,CYB5R1,NLRP6,RIT2,S100A8,TAB1,SACM1L,GNAZ,TAPBPL,SELENOI,DIPK2A,PPIA,PIK3R1,RTN4,MGAT1,PCSK2,RAB4A,TOM1L2,ARB2A,FAM20B,SNX18,CNIH4,SEC62,POMP,AP1M1,VLDLR,C9orf72,LARGE1,TSN,TYROBP,CBLN3,FKBP10,BICD2,AZIN2,FTH1,TRIQK,RANGRF,TXNDC12,TMEM95,PRKCE,PIP4P2,PITPNB,GGTA1,TIMP1,SLC17A5,TNF,SRP54,RBM15B,CLVS2,SST,RNF41,CALU,HBB,OAS1,PEX3,TMEM203,GAL3ST1,LMAN1,TGFB2,ATRAID,CYB5B,GALNT17,CYP2C18,TAF11,AHSA1,TRAPPC4,TMEM50B,PIGY,UFL1,RAB23,DENND6B,GKAP1,ZDHHC17,ST6GAL1,SCG5,IL23A,FGF23,ARRDC3,RAB22A,DNAJB2,RNASET2,ATP1A3,TMEM208,VEZT,CDC42,ATP6V0E1,SLC2A3,ST6GALNAC3,TMEM199,TRAPPC10,TMEM127,SERPINI1,CAV1,SCD5,LITAF,SERPINB1,DNAJC1,GALNT4,ACAT1,ADCY3,HACD3,EPHX1,TMED1,H2BW1,NCK1,TUBB4B,TNFAIP1,GPX7,BET1,CPLX3,DAD1,TLR6,RAF1,UNC45A,ABHD12,RAB2A,BLOC1S5,TSSK1B,RHOG,JMJD8,SNX3,LPAR1,TMED5,CORO1C,PPIB,HUWE1,VPS4B,HSD11B1,RAB30,MX2,TF,NME2,MBLAC2,PLPP6,NCALD,TOR1B,APEH,OR51E2,SEC63,CALML5,EMC4,FITM1,GNAI2,LRRC8B,FABP5,B4GALT6,DRD1,NOC4L,PCYOX1L,PLCB1,JAK1,FITM2,CRAT,MACO1,ABHD2,LMBRD1,PRRT1,B4GALT7,MRLN,VPS16,IZUMO1,SEC14L1,RAB37,LEMD3,TNKS,INPPL1,UNC50,TRIM32,TENT4A,RNF122,RAB29,CETN3,C1GALT1C1,FCER1G,GAD2,RPL10L,PDCD10,CETN2,TMEM38B,ELOVL4,ARFGAP1,MSMO1,GASK1B,CYP39A1,SYS1,LAMTOR2,TLR7,SNAP91,IGFBP4,ST3GAL4,COPS5,TOR2A,PARM1,STUB1,OPRK1,GORASP2,REP15,SRI,SNX2,WTAP,PXYLP1,RP9,MRC1,TRAPPC6B,SERPINB6,UTP15,SLC35B3,HSD17B11,MINAR2,KDSR,THY1,RB1CC1,SLC35A2,BPIFA2,LGALS3,PNPLA8,CPE,TMCC1,TMEM97,PLA2G5,BCL6,GABARAP,RAB6B,VMP1,STX10,ZDHHC4,TERB2,UBE2G2,CHRM3,STX5,RNF148,HSPD1,SEC22A,CD58,LAP3,LRRTM1,SNX17,RAB3D,TSPAN5,CYP4F22,LY96,SVOP,ZDHHC24,ACTR2,PRELP,MINDY3,HS3ST5,EDEM3,GLCE,IFT57,TICAM2,PTDSS1,LUM,GPR85,TMEM167B,STAMBPL1,PHF7,HDAC6,MX1,DNAJC3,SERPINA3,PACSIN3,COPS4,BSCL2,FA2H,GOLGA5,USP8,KPNA2,CAV2,NUP35,CD36,PTHLH,LHB,CHST9,SPCS1,ANXA4,STAMBP,VAMP2,AQP2,LGI1,SDC2,CDKN1B,G2E3,GALNT12,SEMA4C,LAMP2,GTPBP2,SYNCRIP,WDR83OS,ZDHHC16,SLMAP,UPK1A,TRAPPC3,RND2,LAMP5,SNX14,PICALM,STX18,PRDX6,ATP1A2,MGAT4A,TRAM1,NCSTN,SH3BP4,SOD3,ENTPD4,ATAT1,SNX20,NOS1AP,UBAC2,DEFB1,FAXDC2,TMED4,VAMP5,KLK6,CXCL1,OGN,LYPLA2,COMMD9,EHD1,CARD19,CYP4V2,ARCN1,XXYLT1,RNF11,B4GAT1,PLP2,EXOC3,CYP1A1,HRAS,CD40LG,CDAN1,CSH1,NUP153,EXTL2,HILPDA,ATP1A1,CNPY3,GANAB,NXT2,PSKH1,NUS1,LAMTOR1,TIMP3,IL12A,PADI2,NUDT9,KLK3,CHMP2B,STX8,AP1AR,GPR89A,GPC4,PLAGL1,FKBP14,RGMA,FUT1,GNPNAT1,LAPTM4A,LGI3,ARF1,APH1A,CCR5,ACSL4,SCAMP5,SERPINA5,PGRMC1,AGPAT1,SFT2D2,TVP23B,CSTB,HTRA2,SERPINB10,STX1A,YPEL5,SGMS2,RAB9A,TMEM87A,CHST2,MCOLN1,CHMP2A,POMT2,AVPR1B,SUMO1,CTSB,POR,OCRL,WNT7A,KCTD17,TBC1D5,LRP12,PDIA6,RABAC1,LYZ,PTP4A2,CD1D,CBL,CCND1,LYZL4,TPPP,CCDC22,HSPA13,XPOT,CYTH1,RASD1,STARD4,KRAS,BANF1,TRA2B,INPP5E,TMT1B,SFTPD,SLC4A8,ENY2,AP2S1,FKTN,CREB3,CBX5,RAN,SELENOF,ATP6V1D,SPRED2,LMNB1,TRIM3,LYNX1,BFAR,CYBC1,BAX,UGT1A1,STX16,EI24,JPH4,CX3CR1,CHID1,WDR83,CEP85,EHBP1,HFE,SLC39A7,GABBR1,TMEM14A,HMOX2,DPEP3,NEU1,CXCL14,RNF128,SYVN1,MREG,EIF5A2,SIAH2,LDLRAD4,LTBR,ACHE,CHMP1B,OLR1,SPTAN1,NKIRAS1,B2M,PIGC,NECAP2,PGA4,FKBP1A,CTTNBP2,AP3S2,CCAR1,TLR8,PSENEN,TMCC2,ANKRD50,RAB1A,CH25H,CYP4F8,VAC14,MBL2,MYO1B,DUOXA2,ZDHHC8,G6PC3,VIPAS39,B3GALNT1,IDH1,HSP90AA1,SYT2,ASB11,CLBA1,KCNG3,TRAPPC1,TBC1D17,UGCG,SELENOP,TPBG,CYB5D2,PDCD1LG2,PGM1,MYO6,ZNF622,RPL4,UBXN2B,RETSAT,LILRA3,AFTPH,MAP2K1,SERPIND1,PLEKHF1,RAB8B,RAB19,RNF167,OVGP1,TSNAX,TMED3,HDAC5,CTSD,ALB,COL1A2,CTNNA1,VTA1,GCC1,MARCHF3,ARHGAP21,MTMR2,SMAD1,DIPK1A,ZDHHC14,DPY30,ADRB1,TUSC3,CCT8,EMC8,IL15RA,EMP2,FADS2,CTSA,AGR2,TMEM59L,UBB,NECAP1,IFNAR1,TRAPPC13,TAB2,TMEM106B,VKORC1L1,OST4,OLFM3,RPS27A,SYBU,ABHD17A,LYSET,UBIAD1,BAK1,CLDN14,SLPI,ARF6,SSR2,DNM2,CYP2C9,CLCN6,BRI3,RAB31,ELOVL6,TOR4A,ADTRP,ARL6IP5,RDH12,RGS19,OSBP,SLC35F1,MRPS23,HPS6,SYNGR1,GZMK,TMEM30A,GOSR1,P4HA2,PLCB2,GDI2,MYD88,KLK9,ZBED1,SPCS2,DHRS1,PLA2G4B,CHST11,ST8SIA5,KPNA1,GGCX,STXBP1,F10,SERINC3,FSTL1,SELENOM,DCLRE1C,CCDC3,SIX5,MMP9,EXT1,RACGAP1,SEPTIN6,CCDC47,NDST1,THAP7,SCAMP2,RAB13,DHRS3,LHFPL2,FMO2,USE1,PRL,HACD2,SLC51A,YKT6,LYZL6,GHRL,VAMP1,TMEM108,LACC1,SRP72,WASL,FGR,MSRB3,SLC35E1,MARCHF9,SYNDIG1,HP,NIPA2,CYP3A43,SRPRB,MLC1,VAPB,FKBP2,HACD1,DHRS7B,GOLGA7B,PDLIM4,IFI27,HSPA5,SRD5A3,TAS2R16,DNAJC5,ALKBH5,RTCB,CPTP,RARRES2,SLC6A4,HSP90AB1,FURIN,CYP2F1,CAND1,TREML1,MTMR6,ERO1A,ATP6V1G2,SDCBP,XRCC5,RHOU,SHISA2,RER1,GALNT2,HSD17B3,EMC10,FATE1,MYRF,IFI6,CARTPT,TMPO,PRDX4,RGP1,RAB40AL,CCDC134,RPS7,B3GNT2,JKAMP,CYP2C8,IL2RB,EVA1A,RAB3B,CD274,TLR2,AP1S2,LDLR,WDR44,PSMD14,SELL,RDH11,CLN8,ABCF1,SYPL1,TUBA1A,ICA1,F9,TRAM2,CCDC32,CLRN1,BOK,FDFT1,ROGDI,CHP1,CHPF,ZNRF1,AGTRAP,FTL,EEF1B2,NRSN2,SLC35E4,FBXW7,OPRM1,NSG1,DDIT3,NDST3,UBXN6,CD2,PHB1,ST3GAL2,CAMK2G,GCHFR,TEX264,GPC1,RHOBTB1,DNAJC2,RAB14,CAPN2,CASC3,LAMTOR3,CD9,ESYT1,FUT9,CYP2D6,ALG11,BET1L,RNF103,GRIA1,RABL3,CYB5R4,MT3,CYP3A5,BEND5,TUBG1,SGIP1,NAA11,VEGFA,GOSR2,COTL1,SFTPA1,ANXA7,EEF2,SELENOS,TMEM45B,PTPN5,VPS26C,RRM1,TMEM106C,SIGLEC5,GJB1,CASP4,MPDU1,PGAM1,DPM2,CTSC,TOM1,TP53,DHRS7,SSR3,SLA2,RAC2,SGMS1,STAU1,PAQR3,OSBPL8,LAMP3,PATE4,PDE9A,PPFIA2,FCGR1A,AP2M1,MOSPD1,ESD,RETREG2,VPS4A,VPS39,ARHGAP1,GPX4,ATG9A,SNAP23,UST,CERS6,FAM241A,ASIC1,SC5D,RINT1,FCMR,VEGFC,IRF7,CDC37L1,SNAPIN,IQSEC1,TECR,TLCD4,YIPF3,TMEM174,SELENON,GLE1,HAX1,MAD2L1BP,PROM1,ANP32A,TMSB4X,RHOB,BARX2,DDRGK1,MGST2,FMO1,GNPTG,HMGB1,SYT4,LRRC8C,PRMT5,SDR16C5,OTULINL,UBE2I,NUDT1,ROCK1,PAK2,CRHR1,F2,NUP50,MIA2,TPT1,SNX1,MTMR12,SNX12,TMX3,SURF4,CHI3L1,UBAP1,MME,MAP1LC3A,STARD3NL,NDFIP1,TMED7,SEC61B,CASP12,CD63,CLCA1,SPTSSA,MPIG6B,CGRRF1,EXOC8,HACD4,VAMP3,TLR1,CMTM6,PRCP,DMPK,ACTL9,RNF26,LEPROTL1,AIG1,AP5S1,S100A11,CTLA4,CHMP5,SAR1B,MARCHF5,COMMD3,CLDN8,HS3ST3A1,PPT1,KDELR2,FZD6,CSGALNACT2,AKR7A2,CREB3L4,GJC1,CTSK,CHST7,SV2B,YIPF5,RPS29,PIGK,PSMD6,TBC1D16,FZR1,CDK1,RAP2A,SVIP,RAB3C,GNAQ,STOM,UBE2D3,VASH1,ORMDL1,MGST3,CSGALNACT1,PLN,JAGN1,VAMP8,TESPA1,APOC2,REEP3,CAV3,TMED9,YIF1A,PYURF,RBMX2,RHEB,RCE1,INPP4A,GPNMB,STK16,MAMDC2,VPS33A,SLC18B1,NUP62,MAP1LC3B,BECN1,EMC2,BORCS5,COL3A1,NME1,MSH6,PDYN,DNAJC10,ACKR3,TMBIM1,CACYBP,PAFAH1B1,GTF3C3,VAMP7,ARPC2,ERLEC1,GLT8D1,GCA,CYB561D2,FAM91A1,SPCS3,TNFAIP6,HEBP2,WSCD1,MAPRE1,PNP,ASTN1,STBD1,CHPF2,CBX3,SPON1,RAP1B,TOR3A,FLRT3,HAS3,PSEN2,PML,IRAK4,ILVBL,TNKS2,BACE1,TMEM39A,TMUB1,CCDC186,RDH10,GSTP1,CYP4F12,FOS,DNAJC25,USP6NL,B4GALT4,REEP6,CAB39,ELOVL3,PRNP,LRRC8D,CLVS1,LST1,NRM,CYTH2,TCP1,MOXD1,TMEM179B,PGAP4,IGF1,TRIM36,OLA1,RETREG3,SYNGR3,NPC2,EEF1A1,NFE2L2,GABARAPL1,FUT8,FBXW11,RNF115,TUBB,RAB11A,SERINC1,EMC6,IPO8,STT3A,REEP4,RAB28,RAB11B,PSMA2,DUSP26,GIMAP2,UFM1,EMC1,MGAT5B,NPY,PSMD1,S100A6,RAB32,TRIM22,RAB6A,CIDEB,NXT1,DERL2,MYORG,SEC11A,RSAD2,STK26,TMT1A,PIGW,LRP10,PRDX3,GAS8,PYCARD,TMEM100,BNIP3L,QPCTL,MZB1,HSD17B6,FAM8A1,RPS26,TMEM190,CHST10,NDUFC2,TGFB3,RPN1,PDIA3,FMOD,TRAF6,DBH,CYP17A1,GLIPR1,SRP14,PAFAH1B2,PICK1,CDNF,SEC22C,RPL27,PCYT1B,ARHGAP5,B3GALT2,TAPT1,ILF2,DERL1,FGL2,GAPDH,SEC61G,GDPD3,DTL,ELOVL7,ST3GAL5,ST8SIA4,TFRC,CCDC25,SNX10,CHMP4C,KLK5,PTGDS,SLC31A1,LBR,PSMB1,ATP6V1C1,SEC61A1,VPS26A,AQP4,FAF2,FLRT2,RETREG1,BST2,HEXB,MIF,TMEM168,SPTSSB,SCG3,GCNT3,CALY,F7,GALNT1,TMEM33,STIM1,GAPT,PTN,TAPBP,SLC66A2,NLRP3,HYAL2,RAB5A,MTM1,TRIM27,ALG2,PSMC3,AMELX,RNF139,CREG2,CCT2,LRP6,TRIM23,VPS26B |
| 3.493e-17 | -37.89 | NCL (nucleolin) | protein interactions | 4691 | 708 | 301 | 19454 | 5460 |
SPOP,EIF3G,RC3H2,IGF2BP1,UBE2H,RPF2,SLC25A1,SMARCA5,RPL7A,RPS17,KCTD9,SMURF1,SRPK2,UQCRC2,PSPC1,RPS3,ZNF330,FGFBP1,MACROH2A1,RPA2,RNF146,HEXIM1,UBE2M,AGO1,CFTR,RPS15,ZC3H15,HSPA5,BAP1,RPL27,NBN,PML,EXOSC4,RNF113A,CCDC65,SNRNP70,RPL24,RPS2,RPL10A,FAM20C,PPM1D,COPS5,CD81,CSNK2A1,API5,GAPDH,CAND1,RPS16,DNAJC1,FZR1,RBM42,TMPO,CDC5L,SURF6,SYNCRIP,ALYREF,CD4,ARL4D,TFCP2,DNAJC2,RNF8,UBL4A,TP53,H2AX,NEDD8,HNRNPK,MEPCE,RPL17,RPL3,DHX9,FTSJ3,S100A11,H1-10,PSMD14,RPS26,ICAM1,POLR1B,RCL1,H1-1,MYC,HNRNPAB,RUSC2,BTF3,BAG3,CPSF2,PTPRZ1,POLR2B,CBX5,ESR2,APEX1,VDAC2,IRF2,CMTR1,PRMT5,SF3B4,GTF2F1,EIF4B,PIH1D1,RPL27A,MTF1,NUP62,UFL1,STAU1,OXCT1,ITGAV,MRPS7,XRCC5,HSPA8,RAB5A,DDX5,AGR2,MGMT,POU5F1,DRG1,IFI16,DCAF4L2,DDX50,WWP2,RPL6,CTNNB1,DDRGK1,HNRNPL,RPS10,SUMO2,LYAR,PTK7,SWAP70,SRSF1,EED,MAGED2,SMNDC1,RPS23,RPL18,ARFGEF1,SUPT5H,H1-3,DNAJC25,SOX2,ISG15,EEF2,RPS7,KRAS,NUP42,RPS4X,RPL28,RPL31,TOP2B,PABPC1,RPAP3,NRP1,CDC73,DNAJC19,PPIG,FBXO7,DNAJC8,PPP1CC,NONO,NDN,COPE,RPL13A,DEK,RPL22,CCNF,OPTN,METAP2,PRKRA,RPS20,RPS12,CDK1,MRPS34,LMNA,METTL14,RPL26L1,RPLP0,ATG16L1,RPS14,UBA52,SNRPN,CDK7,EIF5B,NPM3,DGCR8,HMGB1,RPL4,FBXW7,PIAS1,UTP23,AATF,BRIX1,RPA3,SIRT7,PNO1,CLK1,MTDH,GRSF1,TLE1,HDAC6,ZMYND11,RPL35A,DCUN1D1,TOP1,MDM2,CDK9,NOP9,RPL12,AIFM1,RLIG1,SRP14,RCHY1,ILF2,SRP72,FBP1,MAP2K3,RPL15,HUWE1,VRK1,THRAP3,NOC4L,FBXO25,RPS13,MDC1,MSH6,FAF1,PPP1R12A,RPL23A,FYTTD1,BRCA1,HSP90AA1,RPS5,SP1,RIT1,CUL3,CUL2,ZNF668,SAMHD1,IRF1,TOMM40,RFXAP,RPL35,ACTB,CHCHD3,RPL19,ERH,RAN,UBE2S,RPL37A,SNRPD2,SNRPD1,SEC61B,RPS9,USP39,KCTD12,H1-5,WDR77,ACTL6A,PPP1CB,PRDX3,SUPT4H1,CDKN1A,GPC1,NOP53,G3BP2,TERT,PSMA3,DDX23,HNRNPD,MRPS26,RPL23,HMGA1,PRPF19,PIK3R1,HNRNPA1,EIF3D,RPL7,SPTAN1,KCTD10,DHX15,RPL8,FOLR1,RPL9,PHB1,MRTO4,RPLP1,EZH2,CHMP4C,RPS11,RAF1,B3GNT2,OTUD6B,ACTN4,LASP1,TNF,GNL1,TRIM37,UBE2A,RFC3,ANP32B,HSPD1,HNRNPA2B1,PPAN,RPS24 |
| 3.692e-17 | -37.84 | UPF1 (UPF1 RNA helicase and ATPase) | protein interactions | 5976 | 552 | 246 | 19454 | 5460 |
TLR9,RC3H2,SPOP,UBE2H,IGF2BP1,ELAVL2,RPL7A,TIA1,RPGRIP1L,ROCK1,RPS3,PSPC1,CSNK2B,EIF2S2,HBB,RPA2,HECTD1,MIR7-1,KLF4,DYRK2,SCLT1,MIR21,MIR34B,CFTR,AGO1,MIR29A,MIR107,PML,MIR10B,BAP1,RNF113A,SMG5,EXOSC4,LSM12,CHCHD1,SNRNP70,SMG8,E4F1,EDC3,COPS5,CSNK2A1,MIRLET7G,GNPTG,RPS16,CAND1,FZR1,SURF6,CDC5L,MIR429,ALYREF,SYNCRIP,DXO,NUPR1,HBP1,TP53,STRBP,H2AX,HNRNPK,RPL17,MIR16-2,MIRLET7C,SRSF12,BHLHE40,MIR200A,MIR9-3,DHX9,FBXW11,H1-1,NSA2,OAZ1,HNRNPAB,HNRNPC,MYC,SNRPB,BTF3,TAX1BP1,CMTR1,LMBR1L,MIRLET7B,CNDP2,NUFIP2,ACSS2,PABPC5,STAU1,UFL1,FXR2,HNRNPA0,SAP18,XRCC5,PYM1,HIRA,AKAP1,EP300,DDX5,HSPA8,HDAC5,AGR2,MIR31,AK2,MAGOH,MIR140,POU5F1,MIR221,WWP2,RPL6,MIR143,IFI16,CNOT2,DDRGK1,MIR29C,CPEB1,XPO1,SUMO2,MIR9-1,LYAR,PAIP1,EIF2S1,HNRNPL,HSP90AB1,PEG10,FUBP3,SRSF1,MIR214,TOP3B,EEF2,PAIP2B,MIR222,SOX2,RUVBL1,NUP42,MIR155,DCP2,KRAS,H1-6,HNRNPDL,PABPC1,RBM3,LSM14A,RPL31,MIR206,RUVBL2,EWSR1,IVNS1ABP,MIR145,CASC3,PAIP2,NDUFB10,PPP1CC,RPL26,MAGOHB,VIRMA,SMAP2,EIF4A3,METAP2,CCNF,MIR16-1,RPS20,PTEN,TPT1,SNRPN,RBFOX2,RBMS2,MIR1-2,MIR7-3,FBXW7,DGCR8,LSM8,AATF,MIR205,SIRT7,RPA3,MIR34C,MIRLET7I,MNS1,MIR34A,SMG9,GRSF1,MOV10,HDAC6,CGAS,NCBP2,MIR106B,HRAS,MIR25,PRR3,MIR17,MIR20A,ILF2,YTHDF2,MAP1LC3B,MIR15A,APOBEC3D,MIR200C,THRAP3,TTC4,RNF20,PPP1R12A,DCAF4,ZCRB1,BRCA1,MIR363,CUL3,MIR98,RNF40,RPF1,EIF4A2,PRRC2A,MIRLET7D,FAU,LARP4B,ETF1,CDKN1A,LZTFL1,NOP53,YTHDF1,MIR106A,G3BP2,UPF3B,EXD2,TERT,MIR1-1,RB1CC1,TRA2A,HNRNPA1,ZNF576,CEP19,PHB1,MIR7-2,MIR141,TSG101,STIM1,EZH2,E2F4,RAF1,UFM1,G3BP1,IMMP2L,HNRNPA2B1,ATF3,PPAN,GADD45A,NUDT5,TRIP4,COX8A,SRSF7,ZC3H7A |
| 4.809e-17 | -37.57 | ITGA4 (integrin subunit alpha 4) | protein interactions | 3676 | 539 | 241 | 19454 | 5460 |
SDHB,EEF1B2,SYNCRIP,ALYREF,RAP1B,RAC2,RPS16,MIF,MYL12A,FCGR2A,CD81,GAPDH,SNRNP70,H2AC4,SMCHD1,RPS2,LSM3,RPL10A,ABCE1,H3C1,HNRNPK,KPNA2,CSE1L,CAPZA1,H2BC14,RPL17,RPSA,TFRC,DDX42,ARPC3,RPS3,SF3B6,PSMA6,PAFAH1B3,CSNK2B,BUB3,PSMB2,RAB2A,GSTK1,RPL7A,TIA1,CFL1,H2BC9,RPS17,IGF2BP1,PRDX6,ST8SIA4,EIF4E,MARS1,AKR7A2,CAPN1,CD2AP,NTPCR,SDCBP,UBE2M,GSTP1,FUBP3,EED,RPS10,TTC9C,HNRNPL,EIF2S1,SNRPA1,SNRPD3,TCP1,CCT7,CHMP2A,HSP90AB1,RAB5C,YWHAG,XPO1,LCN6,DDX1,CBL,DRG1,YWHAB,HSPB1,PABPC1,CCT8,RBM3,EWSR1,PICK1,PSMA1,HNRNPF,RPL28,RPS4X,VAMP8,HNRNPDL,UBL5,H1-3,RPS7,EEF2,TUBB4B,PDHA1,RPL18,VDAC2,ATP5F1B,TAGLN2,MATR3,PSMB6,RPL10,LDHB,HNRNPC,HNRNPAB,CCT2,DDX39B,XRCC5,RPS28,HSPA8,DDX5,HNRNPA0,BOLA2B,PHB2,ITGAV,LYPLA2,RPL27A,SYK,HBE1,CSNK1A1,HRAS,RPL12,PSMB1,ARF6,TOP1,MRPS23,SLC2A1,ESYT1,DNAJC7,H2AC25,RPL23A,SEPTIN7,HSD17B10,HSPE1,RPS13,H2AC6,EIF3E,CCT5,NDUFA2,EEF1A1,NDUFS3,ILF2,EIF4A3,ENO1,ACAT1,RPS20,MSN,LDHA,PNP,SNX3,RPL13A,UBB,RPL22,RPL26,NONO,GMPS,LGALS8,NAPA,AP2A1,MAPRE1,INPPL1,PPIH,PIK3R2,HMGB1,RPL4,RPS14,MYL12B,EEF1E1,UBA52,LPXN,EDDM3B,LMNA,CDK1,PICALM,STOM,RPLP0,HNRNPH3,RPL9,DNM2,RPL8,PPP2CB,PHB1,TYMS,XPO5,KRT8,HP1BP3,CCAR2,CACYBP,PPIA,DHX15,PSMD3,PRDX1,HNRNPA1,RAP2B,HBA1,PDCD10,HNRNPD,NQO1,RPL23,SLC25A5,HSPD1,HNRNPA2B1,MADCAM1,RPS24,G3BP1,RPS27A,MCM6,ANP32B,SSRP1,NAA15,LYPLA1,PPP2R1A,ACTN4,RPS11,AP2S1,ARF1,RAN,EIF3K,SNRPD1,AP2M1,SNRPD2,SEC61B,RPS9,PRDX2,ACTB,RPL35,ACO2,PYCR1,MCM3,MCM4,YWHAZ,LMNB1,RPS5,PSMA3,SRI,SRM,TGFB1I1,H1-5,PRDX3,ATP5PO,ARCN1,MYL6 |
| 4.996e-17 | -37.54 | COX15 (cytochrome c oxidase assembly homolog COX15) | protein interactions | 1355 | 346 | 170 | 19454 | 5460 |
ATP1A1,OAT,MRPS16,RPL26,NDUFAF2,SMARCA5,PYCR2,TECR,TXN,MRPS21,LDHA,TMOD3,SLC25A4,CPT2,RTRAF,MRPS28,GANAB,CHCHD6,SLC1A1,PTPMT1,UQCRC2,SF3B6,CCNF,EIF4A3,EIF2AK2,HNRNPH3,RPL26L1,CYC1,MACROH2A2,RPA2,CDK1,MRPS34,METTL14,HSP90B1,SAMM50,CDK7,TIMMDC1,EEF1E1,NHP2,PDHB,SLC25A51,MRPL41,VIPR1,PRDX6,DLAT,RPL27,RPA3,BANF1,DNAJC4,RPL10A,SLC2A1,H2AC4,COX5A,DKC1,ATP5PD,MRPS23,SURF6,PLGRKT,SLC25A12,RPL35A,MRPL50,TOP1,LDLR,AIFM1,MRPS9,SSBP1,RPL12,ALYREF,COX4I1,RPL32,ILF2,MRPL49,TFRC,NEFL,NDUFS3,APOO,ATP5PB,FAM162A,NDUFA2,PDE2A,FKBP8,PRDX4,THRAP3,DNAJC30,CLPB,MRPS18B,SFXN1,SLC25A11,ATP5PF,HTRA2,SERPINH1,RIT1,CHTOP,H1-10,MYO6,LMNB1,H2AZ2,MRPS25,PSMA4,HNRNPAB,CHCHD3,NDUFAF4,GNB1,ERH,PARL,RPL35,DYNLL1,RBBP4,LAMTOR3,VDAC2,TACO1,ARF1,DLST,CCDC90B,NDUFA5,SLC25A3,TIMM13,PRDX3,MRPL12,TIMM29,NDUFAF3,MTX2,SAP18,MRPS7,NDUFS2,HSCB,PHB2,BOLA2B,AKAP1,TSPAN15,MRPS26,PPM1B,HNRNPA1,NDUFV2,DDRGK1,QPCTL,STOML2,MRPS35,ERLIN1,NDUFS8,PPIA,COX14,RMND1,NOP58,PHB1,NDUFA12,CRELD1,PLD3,CYB5B,RPN1,H2BC1,NDUFS6,AQP3,TOMM7,ERLIN2,MRPS17,RPL28,IMMP2L,HNRNPDL,FLOT1,KRAS,VDAC1,ETFA,KGD4,RTCB,SLC25A5,SCYL2,NDUFA4,PABPC1,TOP2B |
| 5.011e-17 | -37.53 | HSF1 (heat shock transcription factor 1) | protein interactions | 3297 | 601 | 263 | 19454 | 5460 |
TECR,LDHA,ALB,TRIM24,MSN,UBE2I,POLR3H,GSK3A,ENO1,EIF4A3,TMSB4X,TUBA1B,STUB1,PIM2,IVNS1ABP,DNAJC8,TUFM,GMPS,ATP5F1A,DHPS,ZNF687,SEC13,CDC16,RPL4,FBXW7,SMC4,GTF2I,EIF5B,MNS1,RPLP0,PDCL,HSP90B1,GOLGA5,JUP,MRPS34,PAK5,UBA52,TPT1,SEC22B,CWC15,G6PD,MAPRE2,TOP1,COG1,DECR2,EIF4E2,EEF1AKMT3,RPL12,HACD3,SSU72,NME2,GTF2A2,KXD1,MOV10,H2AC14,PTGES3,OLA1,RNF20,THRAP3,CTNNBL1,TSSC4,ZC3H11A,SFXN1,SLC25A10,DTD1,ALPL,ILF2,DMAP1,EEF1A1,AKR1C1,CCT5,H2AJ,USP5,MAD2L1,CHCHD3,TUBB,RPL35,ACTB,AKR1C2,RPS9,RPL37A,ENO2,RAN,RAB28,CPSF1,S100A6,HSP90AA1,YWHAZ,MCM4,MCM3,RNF40,TOMM40,CFAP20,G3BP2,PSMC1,ATP2C1,SLC25A3,PCLAF,MED23,TIMM29,DHX15,HSBP1,RPL7,HYPK,SNX1,ATP6V1A,TYMS,PPP2CB,RPL8,RPL9,HNRNPD,LYZ,PSMD10,TRA2A,HNRNPA1,VPS26A,TAF7,SSRP1,RFC3,PSMD12,MCM6,RPS27A,GTF3C3,BAG2,UBE3A,RPS24,SRSF7,PCNA,HECTD3,HNRNPA2B1,ARGLU1,CHST10,MORC2,SLC25A5,MTMR2,PPID,ACTN4,CDC20,ADRM1,IRF2BP1,BUB3,SEC61A1,LIG3,RPS3,UQCRC2,RBM7,CALU,ATP1A1,RC3H2,RPL7A,SUB1,SLC25A1,HSPA5,NME4,KDM1A,HSPB2,PML,UGDH,ACACA,ZNF326,LDHAL6B,GTF3C4,SUMO1,AKR7A2,RPS16,CAND1,CDK6,ALYREF,SYNCRIP,GTF2B,USP15,RPL10A,AGPAT1,KPNA1,TAF9,RPS2,SMCHD1,MED27,TPM3,GAPDH,CSNK2A1,ANKMY2,KARS1,CSE1L,KPNA2,H3C1,NUP107,DHX9,RPL3,SLC25A11,PSMC3,TP53,IPO8,RPSA,POLR2B,TRIM29,SNRNP40,MATR3,STAT1,EFHD2,SURF2,VDAC2,MDH1,CRMP1,CHTOP,BAG3,PSMD1,HNRNPAB,LDHB,CREBBP,SAP18,EEF1G,NDUFS2,GON7,SRSF2,TRA2B,DR1,PCGF2,EP300,DDX5,RTL9,HSPA8,SF3B1,XRCC5,CSNK1A1,NUFIP2,NEK7,DHRS4,SEC22A,ZC3H14,HSP90AB1,AASDHPPT,SUMO3,HNRNPL,STX5,S100A8,ANXA4,SRSF1,RPRD1A,HSPB1,DDX1,FKBP4,QPCTL,BTF3L4,RPL6,RAB5C,ZBTB45,RPS4X,RUVBL1,TRIM11,RUVBL2,DNAJB4,EWSR1,PABPC1,ABCF1,AAMP,RPL18,SMARCB1,MTA2,TUBB4B,CBLN4,EEF2,ETFB |
| 5.016e-17 | -37.53 | ribosome | cellular component | GO:0005840 | 234 | 129 | 19108 | 5553 |
RPS10,RPS28,RPL6,RPL8,MRPS26,MRPL16,RPS7,MRPS11,IMP3,RPS26,RPL15,RPS20,PELO,RPL3,RPL12,RPS16,RPL22,MRPL13,MRPS28,MRPL9,MTG2,RPL17,RPS5,RPL26,RPL7L1,MRPL34,MRPS25,NUFIP2,RPL35A,EIF2AK2,RPLP2,RPL23A,RPL7,MTG1,RPS17,MRPS23,MRPS33,MRPL23,RPL13A,RPL10L,RPL31,RPL27,RPL32,HSPA14,MRPL41,ZCCHC17,MRPS21,MRPL11,RPLP1,MRPS18B,MRPL22,RPL19,RPL9,MRPL51,RPL26L1,RPS29,MRPS9,MRPL24,RPS11,ABCE1,MRPL57,RPL29,RPL10,RPS23,MRPS35,RPL18,RPS2,RPLP0,MRPL10,PSMA6,FAU,RPL4,RPL27A,CALR,CHCHD1,RPSA,RPS14,RPL10A,RPS27L,RPL7A,RPS12,NCK1,RPS15,EEF1A1,RPL24,MRPL49,RPS3,RPL23,NR0B1,MRPL53,ELAVL4,AURKAIP1,MRPS34,RPL28,RPS24,RPS13,RBM3,MRPL17,RNF14,MRPL36,MRPL12,ETF1,RSL24D1,MRPL52,UBA52,RPS4X,MRPL33,MT3,MRPS7,RPL35,MPV17L2,MRPL47,RPL37A,MRPS17,APEX1,MRPS16,EIF2D,MRPL20,RNF10,MRPL40,RPL39,MRPL18,RPS9,MRPS18A,EEF2,RPS27A,MRPL50,FUBP3,MRPS18C |
| 5.404e-17 | -37.46 | EWSR1 (EWS RNA binding protein 1) | protein interactions | 2130 | 794 | 330 | 19454 | 5460 |
PCNA,SRSF7,NUDT5,PLSCR1,TRIP4,HNRNPA2B1,ARGLU1,ATF3,SRSF4,RPS27A,ANP32B,RAD21,TRIM37,JUN,RPL29,WDR37,ERLIN2,MARCKSL1,RAF1,KHDC4,STX12,GPBP1L1,ITGB5,SSBP3,SNRPE,EZH2,NGB,TSG101,IGBP1,RPLP2,RPL8,PHB1,PPIA,CACYBP,DHX15,NUP35,COPS7B,CCAR2,SPTAN1,SNX18,HNRNPA1,TRA2A,ZNF207,HMGA1,HMBS,TRIM8,STOML2,HAX1,AHSA1,HNRNPD,MED4,DDX23,TRIM5,CFDP1,RMND5B,ATPAF2,NRBF2,MRPL57,SUPT4H1,SOX21,ACTL6A,KCND3,RAB37,MFAP1,MYL6,NDUFA5,KCTD12,SNRPD2,SNRPD1,NTNG2,BAD,VPS72,PRRC2A,SNRPB2,PRDX2,SMARCE1,RIOK2,RNF40,HNF1B,CUL3,CUL2,PFDN2,ILK,CBR3,PFDN6,BRCA1,DCAF4,YWHAZ,CPNE2,HINT1,PQBP1,SFXN1,OLA1,SMN1,PRDX4,MDC1,PTGES3,RIGI,CTNNBL1,HSPE1,THRAP3,CD2BP2,SMAD1,TMEM126A,FBP1,POLR2G,ILF2,PDLIM4,RAD23B,MYBL2,SEC23A,RPL12,DFFA,EFNA3,TFE3,RCHY1,KRR1,CDK9,PTP4A3,CWC15,DCUN1D1,HDAC6,GTF2E1,GLO1,KXD1,CALR,EIF5A2,POR,PSMD7,KIAA1143,ECD,MNS1,PPM1G,RPA3,SOD1,SIRT7,MBD3,PPP1R2,GTF2I,DGCR8,NPM3,HMGB1,NUCKS1,EDF1,SAP30BP,ATG16L1,RPLP0,HNRNPH3,PAX9,PTP4A2,PICALM,METTL14,GSK3A,GTF2A1,GNPDA1,MSN,CFAP298,UBASH3B,ACAT1,OPTN,CCNF,PELP1,KCNMB1,CTTN,VIRMA,TXN,RUNX1,DNAJC8,GMNN,NONO,SEC13,CA2,CASC3,MAPRE1,SDF2L1,EWSR1,PDIA6,FAM168A,BCL9,RPL31,TFG,HNRNPDL,PRPS1,HNRNPF,KRAS,RUVBL1,VDAC1,HMGN4,MAPK1IP1L,H1-3,TRAF2,SOX2,NCSTN,KIF2A,CSTF2T,RANBP1,ZRANB2,PLS3,SMNDC1,RFX5,RPRD1A,PRCC,SRSF1,ELK1,EIF2S1,RPS10,HNRNPL,SUMO2,SNRPD3,SUMO3,PPIB,YWHAG,DNTTIP1,CTNNB1,DDRGK1,LAMP2,MDFI,WWP2,POU5F1,DDX1,UBFD1,FKBP4,AGR2,SF3B1,HSPA8,YAF2,EP300,DDX5,DDIT3,RFC4,SNRPA,XRCC5,UFL1,SRSF2,FXR2,TRA2B,EYA3,RALYL,SSBP2,TOMM22,PRR13,PIH1D1,CTBP1,ACAA2,PRMT5,SF3B4,GTF2F2,ZHX3,APEX1,MATR3,PCMTD1,SNRNP40,BAG3,SNRPB,MYC,CREBBP,HNRNPAB,LDHB,PSMA4,ELAVL4,MCAT,H2AZ2,MRPS18B,ABCE1,DHX9,MEPCE,NEDD8,KPNA2,CEACAM5,HNRNPK,ESS2,WBP11,SNAP29,MTCH2,TP53,RPSA,HBP1,TSPAN3,RNF8,DISC1,MRPS9,EEF1B2,SYNCRIP,ALYREF,SELENOI,CAND1,COPS5,CD81,API5,GAPDH,CDK12,SMAD4,TPGS2,SNRNP70,PGK1,RNF113A,BAP1,NLE1,IRF3,BNIP3L,HSPA5,HDAC3,STK38,CFTR,SPTBN1,SUMO1,HEXIM1,UBE2M,PRKCA,RPA2,SDCBP,RPRD1B,WWP1,ZNF326,PHAX,SLC1A1,NOPCHAP1,TRAF1,RSL24D1,EIF4H,CHMP5,TIA1,GORASP2,LILRA3,RPL7A,CEP85,UBE2H,SPOP,ATP1B3,RC3H2 |
| 6.677e-17 | -37.25 | NUPR1 (nuclear protein 1, transcriptional regulator) | protein interactions | 26471 | 682 | 291 | 19454 | 5460 |
PPM1B,KDM2A,DDX23,MPHOSPH6,PRPF19,RAP2B,TRA2A,ZNF207,EIF3D,HNRNPA1,SPTAN1,NOP58,DHX15,NUP35,LRWD1,SRSF10,MRTO4,THOC2,HP1BP3,ATP6V1A,KRT8,CTSA,AP2S1,SNRPE,EIF1AX,ERLIN2,MAK16,ACTN4,LASP1,RBBP7,GOLGA7,FLOT1,RFC2,PPWD1,SRSF4,RPS27A,HNRNPA2B1,SRSF7,PCNA,LMNB1,MYO6,F2,CFAP20,MCM3,RFC5,DYNLL1,RBBP4,ACTB,EIF4A2,GNB1,SNRPB2,UBTD1,RAN,CPSF1,GNG12,AP2M1,SNRPD1,APOBEC3C,USP39,MYL6,MFAP1,H1-5,GJC1,PPP1CB,GPC1,RP2,SKP1,THOC3,EMG1,CCDC86,HADHA,TXNL1,ORC5,ERCC3,THOC1,PRNP,TOP1,CGAS,PPP1R18,ARF6,CAV1,CDK9,UBP1,NHEJ1,AIFM1,CTDSPL2,SRP14,H2AZ1,PSMB1,ACTR2,CASK,DDX39A,VRK1,THRAP3,PAK1IP1,CTNNBL1,MDC1,H2AC6,EIF3E,CTNND1,DLG1,PPP1R12A,SEMG2,SEPTIN7,GNG5,CCNY,LGALS8,MAPRE1,PPIG,EPHA2,AP2A1,CDC73,SEC13,RACGAP1,PPP1CC,NONO,KPNA6,YES1,TMOD3,MAGOHB,GNAI2,DEK,EIF2AK2,CTTN,EIF4A3,UBE2I,MSN,LSM2,P3H1,LMNA,CDK1,MACROH2A2,HNRNPH3,PSMC4,CNP,NF2,EIF5B,LSM8,BRIX1,NHP2,PRPF4,RPA3,H2BC12,PPIH,SQSTM1,ARPC2,CRTAP,YWHAB,DDX1,BAZ1B,ACTR3B,UTP6,PPIB,SUMO2,LYAR,SNRPD3,EIF2S1,HNRNPL,SRSF1,SERPINC1,CORO1C,EED,PDHA1,PLS3,RPS23,RANBP1,SUPT5H,NPY5R,KIF2A,NUP37,H1-3,RUVBL1,HNRNPF,TFPI,HNRNPDL,UTP25,POLDIP3,PABPC1,TOP2B,ABCF1,GNA11,RTCB,SEC11A,RUVBL2,POLR1B,DNAJB6,NSA2,EPS8,HNRNPAB,HNRNPC,SNRPB,SNRNP40,MATR3,PSMD4,CAVIN2,CBX5,EFHD2,DLST,SF3B4,SMU1,CTBP1,CAV2,CSNK1A1,NUFIP2,USP6NL,NUP62,CD59,HNRNPA0,TRA2B,FXR2,PACSIN3,SAP18,SPECC1L,XRCC5,DDX39B,SNRPA,EP300,DDX5,EMP3,SF3B1,SMCHD1,NOS1AP,SNRNP70,POLB,KPNA1,API5,COPS5,CSNK2A1,CDC5L,DKC1,TMPO,MYL12A,ALYREF,SSBP1,METAP1,SYNCRIP,CDK6,IK,ARPC3,CAPZA2,DDX42,CBX3,TFCP2,TFRC,PSMC3,GNAI3,TP53,RPSA,WBP11,H2AX,KPNA2,H3C1,CDC40,NUP107,CAPZA1,NOSIP,DHX9,STX18,LSM6,MORF4L1,SMARCA5,RPS17,CFL2,BUB3,DAPK3,RNASEH1,CSTF3,LIG3,SF3B6,GTF2H2,MACROH2A1,CSNK2B,EIF2S2,PSMC5,ZNF326,RPA2,SDCBP,RPRD1B,H2BC11,CSNK1G3,UTP15,PPP1R8,SUMO1,SPTBN1,CDC42,WDR3,WDR55,PML,BANF1,DDX46,HNRNPH2 |
| 6.684e-17 | -37.24 | CANX (calnexin) | protein interactions | 821 | 1210 | 469 | 19454 | 5460 |
LMBR1L,VDAC2,DLST,ESR2,BTF3,LRRC8C,ST3GAL2,MYC,ST3GAL1,CHST9,ZMPSTE24,TMEM179B,SERPINH1,JAGN1,PEBP1,BMPR1A,TMEM106B,ITGAV,CERS6,NDUFS2,UFL1,PHB2,ADRB2,CCDC167,SEC62,GPC4,MRPL12,EDEM3,PPT1,STX5,DUSP6,CD63,SWAP70,RAB1B,NDUFV2,DDRGK1,LAMP2,RAB5C,PEX3,ARMC8,NCK1,EWSR1,SCPEP1,MYO1B,PAK6,NCSTN,DNAJC25,NUP37,EEF2,CSTPP1,SERPINA5,PDHA1,PTRH2,SEC61A1,AMIGO1,UQCRC2,NECTIN2,ACP2,GORASP2,NPTX1,RAB2A,UBE2H,ATP1B3,DERL1,DLAT,BAP1,ITM2B,CLU,CDC42,CYC1,LEMD3,TMEM95,FGFR1,GPR35,SSR1,SLC39A10,RAC2,XXYLT1,BRINP2,ITGA6,UBE2G2,RPL32,SLC38A2,MYL12A,LMAN1,CAND1,TMED9,DPP4,MEPCE,EDEM2,NUP107,ATP5PB,INSIG2,TP53,GNAI3,SLC25A24,SEC61B,S100A6,GRIA1,ABHD12,UBE2V2,B4GAT1,LRRC8A,IP6K1,SPCS1,B4GALT3,MRPL16,ACO2,RPS5,HSP90AA1,SCFD1,ILK,RHOB,CD1D,TRIM5,TXNL1,DUSP9,DNAJC3,PXMP2,CSRP1,NOP53,TOR1AIP2,PGRMC1,HEXB,ELOVL1,SLC25A3,VAPB,ARMCX3,ATP6V1A,CD1A,EGLN3,TMEM237,WDR44,DNAJB9,HNRNPA1,PDIA3,PMP22,RB1CC1,TMEM30A,COTL1,CDK5RAP3,TAS1R2,GAL3ST1,SYPL1,TMED7,AHCYL1,FLOT1,CDK20,SEMA4C,ACTN4,PPP2R1A,FAF2,ERLIN2,IFNGR1,MACO1,DCAKD,B3GNT2,RAF1,ITGB5,RPN1,NDUFS6,CHMP4C,SLC11A2,CCNF,GXYLT1,FERMT2,UQCRQ,VIRMA,COPE,MGST3,RHOJ,IFNAR1,GMNN,HMOX2,CNTNAP1,CDC73,GGCX,ZNF177,SDF2L1,RTN4,SPCS2,RHOU,RPA3,IDH3A,WNT7A,DAD1,TMUB1,LSM8,PDHB,YKT6,FBXW7,ARMCX5,UQCRC1,CDK7,RABL3,SEC22B,ARHGAP1,MET,COX6C,METTL14,SLC12A2,ADAM21,LDLR,TES,EFNA3,PTPN1,NCBP2,MDM2,MSMO1,ANKRD46,HM13,SLC35A5,LAMP3,ATP1B1,SLC25A46,SPATS2L,C1GALT1C1,OSBPL8,POR,GNG5,IGF1R,LIPA,RAB1A,HUWE1,DNAJC30,TOR3A,FAM169A,SERPINA1,TNFAIP8L1,CAMK1,NDUFS3,ATP6AP2,ATP5F1B,RPL39,OST4,TMED5,GABRG2,SLC38A1,ICAM1,SPCS3,POMP,CHTOP,FTSJ3,HDAC5,HSPA8,AKAP1,RAB5A,FOS,EMC1,STAU1,RER1,SSR3,SEC22A,TSHR,CNPY3,OGFOD3,PIH1D1,DIPK2A,CORO1C,PTK7,UQCRH,TOR1B,LANCL1,ADCK1,RHOH,ASIC1,PPIB,CLEC18A,AGR2,SEC11A,PDIA6,TMEM87A,CYP2C9,RINT1,KRAS,GJB1,CHCHD2,VDAC1,ISG15,FUT9,SOX2,KIF2A,NETO2,STBD1,TAPT1,RND3,NCR3,SEC61G,CD1E,PSMA6,TIA1,SLC6A4,C9orf72,MAT2A,ATP1A1,CALU,DNAJC10,ACP5,RNF113A,TMX2,APMAP,BANF1,TOMM20,HSPA5,ABCC2,GABRA1,CFTR,KLRD1,SUMO1,UBE2M,CHRNB2,CD46,RPA2,IDH2,RNF128,GLT8D1,STT3A,COQ8A,CAMLG,COMT,COX4I1,TMPO,SELENOI,DNAJC1,SVIP,CSNK2A1,EDEM1,FAM20C,FAM187B,STX18,SLC16A1,PCYOX1L,ATP2B4,PAQR9,CHST2,SLC6A8,UST,FKBP8,SRPRB,L1CAM,CD1B,TMEM33,KPNA2,PREB,SNAP29,UBL4A,SELENOF,TFRC,ACVR1,FZD6,CYB5R3,PIGK,GNB1,CHP1,DYNLL1,GGH,VEZT,KDSR,NOP16,CUL3,FAM107A,NTRK3,MYO6,LMNB1,VLDLR,HADHA,FBXL4,NPTN,GPC1,TMUB2,PRDX3,RND2,NDUFA5,FAM3C,ABCB1,ATP5PO,APOBEC3C,CYB5A,PHB1,ERLIN1,NDUFS8,OS9,TMEM248,OCRL,SPTAN1,UBXN6,MARCHF5,DPY30,RHOG,TRAF6,COX8A,ERP29,NDUFA4,TMT1A,HS2ST1,RNF26,RETREG1,EMC8,LAMB2,LASP1,TRIM37,ETFA,YIPF3,LGR4,ENPP4,CYB5B,PLD3,MOXD1,EZH2,STIM1,GANAB,PLP1,TECR,SEC63,ATP5F1A,TUFM,NDUFB10,CTSD,NAPA,TMEM255A,NCKIPSD,TMEM106C,LGALS8,DPEP3,MTDH,SIRT7,POLDIP2,TMEM209,SLC5A6,CERS2,SMC4,PDCL,MANBAL,GRM2,HSP90B1,HSD17B11,LMBRD1,SEC23A,CDCA3,SRPRA,HACD3,EHBP1,ATP5PD,ARF6,ALCAM,PRNP,HDAC6,TMEM199,CALR,EI24,EMC4,STYK1,SLC2A1,ESYT1,BSCL2,PC,EMC2,TMX3,NSDHL,SLC25A10,TF,CLEC2B,LBR,CCDC47,TMEM101,SRP72,POMT2,KLRC2,HSPA13 |
| 6.884e-17 | -37.21 | RPS9 (ribosomal protein S9) | protein interactions | 6203 | 482 | 220 | 19454 | 5460 |
BRCA1,RIT1,RPS5,EXOC8,CUL3,NOP16,CUL2,ACO2,RPS29,ZNF668,RPL35,RPL7L1,ACTB,RPL19,FAU,SEC61B,RPL37A,EMC9,FKBP1A,H1-5,CDKN1A,NOP53,G3BP2,PPM1B,RPL23,HNRNPD,MRPS26,RB1CC1,MRPS35,EIF3D,HNRNPA1,RPL7,PHB1,RPL8,FOLR1,RPL9,HP1BP3,RPLP2,CHMP4C,EZH2,POLR2C,RPS11,B3GNT2,DSTYK,ACTN4,EMC8,G3BP1,UBE2A,RPS24,PPP1CC,USP14,AR,RPL26,RPL13A,NDN,VIRMA,RPL22,METAP2,EIF4A3,CCNF,RPS20,PTEN,RPS12,PRKRA,GSK3A,METTL14,MRPS34,RPLP0,RPL26L1,RPS14,CDK7,RPL4,FBXW7,HMGB1,MRPL17,NPM3,AATF,BRIX1,PNO1,RPA3,MPHOSPH10,ECD,EMC4,HDAC6,RPL35A,MRPL24,MRPS23,CDK9,RCHY1,KRR1,RPL12,PRR3,MRPL49,MRPL51,SRP72,ILF2,FBP1,RPL15,VRK1,CTNNBL1,HUWE1,EIF3E,MRPS18C,RPS13,RPL23A,MRPS25,FTSJ3,ATG3,H1-1,RPS26,ICAM1,COP1,SFN,MYC,RPL39,BTF3,MATR3,RPL10,CMTR1,MRPL13,PIH1D1,EIF4B,FBXO42,PAFAH1B1,RPL27A,MTF1,STAU1,UFL1,EIF1B,MRPS7,RPS28,PYM1,HSPA8,AGR2,MAGOH,DRG1,PEX3,RPL6,WWP2,DDX50,DDRGK1,NGDN,XPO1,SNRPA1,LYAR,RPS10,HNRNPL,RPS23,RPL18,RPS7,KRAS,RPS4X,PABPC1,RPL31,ATP1B3,UBE2H,RPL7A,ZSCAN25,RPS17,MRPS21,SMURF1,PSPC1,RPS3,MRPS28,WWP1,RPA2,ZNF770,HECTD1,HEXIM1,UBE2M,CFTR,MRPL41,RPS15,HSPA5,PML,NLE1,RPL27,BAP1,RNF113A,SNRNP70,RPL24,TUBG1,RPL10A,USP15,RPS2,ENY2,CMSS1,GAPDH,COPS5,CSNK2A1,CD81,RPS16,CAND1,FZR1,DKC1,TMPO,RBM42,RPL32,MRPS9,SYNCRIP,CD4,DNAJC2,RBM34,TFCP2,RNF8,TP53,RPSA,UBL4A,KBTBD4,H2AX,H3C1,MRPS33,RPL17,MEPCE,SRSF12,SNIP1,MRPL52,DHX9,RPL3,MRPS18B |
| 7.020e-17 | -37.20 | RC3H2 (ring finger and CCCH-type domains 2) | protein interactions | 54542 | 665 | 285 | 19454 | 5460 |
ZC3H7A,BAG2,RPS24,SRSF7,MRPS11,SLC25A5,HNRNPA2B1,SRSF4,RPS27A,MRPS17,UFM1,G3BP1,PPP2R1A,RPL29,RAF1,RPS11,SNRPE,EZH2,VPS33A,RPLP1,RPLP2,RPL8,WDR6,SP2,MRTO4,MYEF2,SRSF10,ZNF593,DHX15,NOP58,RPL7,CCAR2,SPTAN1,HNRNPA1,PRPF19,TRIM8,MRPS35,STOML2,HNRNPD,HAX1,MRPS26,RPL23,ZCCHC9,CCDC86,MCRIP2,UPF3B,G3BP2,YTHDF1,TIMM13,WDR77,SLC25A3,LARP4B,SNRPD2,RPL37A,SNRPD1,FAU,UBE2V2,RPL19,PRRC2A,ERH,MRPL23,DYNLL1,TUBB,SPINDOC,RPL35,MRPL16,RFC5,NOP16,HSP90AA1,PFDN2,PFDN4,RPS5,PFDN6,DCAF4,RPL23A,NKRF,CNOT6L,CTNND1,MRPL22,RPS13,EIF3E,CNOT7,FARSA,NOC4L,THRAP3,EEF1A1,UBE2V1,RPL15,MRPL11,CCT5,YTHDF2,ILF2,SRP72,UBE2B,PSMB1,AIFM1,RPL12,SRP14,HACD3,H2AZ1,NCBP2,MRPS23,NOP9,MRPL50,GRSF1,MOV10,MTDH,PRPF4,NHP2,POLDIP2,BRIX1,EIF5B,RPL4,RPS14,RBFOX2,PSMC4,SNRPN,RPLP0,GSK3A,PRKRA,RTRAF,UBE2I,RPS20,RPS12,SMAP2,TUBA1B,EIF4A3,TECR,VIRMA,RPL22,TXN,RPL13A,ATP5F1A,PPP1CC,NONO,PYCR2,AP2A1,CDC73,PAIP2,IVNS1ABP,ZNHIT3,EWSR1,TRIM21,PDIA6,RTCB,FBXO3,RPL31,CCT8,PABPC1,RBM3,LSM14A,PFDN1,RPS4X,RPL28,POLDIP3,HNRNPDL,HNRNPF,CRTC2,TUBA1A,EEF2,RPS7,TOP3B,TRMT1L,RPS23,RPL18,TUBB4B,WDR82,CORO1C,TRAPPC10,SRSF1,FUBP3,HSP90AB1,CCT7,RPS10,HNRNPL,FAM98A,TCP1,LYAR,SNRPD3,SNRPA1,YWHAG,CNOT8,QPCTL,IQSEC1,DDX50,CNOT2,UBE2E2,PFDN5,DDX1,HSPB1,YWHAB,HSPA8,SF3B1,PYM1,SLU7,SNRPA,RPS28,XRCC5,HNRNPA0,TRA2B,FXR2,SRSF2,STAU1,PHB2,MRPL12,PABPC5,RPL27A,EIF4B,NUFIP2,PRMT5,RPL10,MATR3,ATP5F1B,SNRNP40,BAG3,HNRNPAB,HNRNPC,POLR1B,DNAJB6,RCL1,CCT2,CKB,RBM27,MRPS25,H1-10,RPL3,MRPS18B,DHX9,MRPL52,MAP1B,SLC25A11,RPL17,CAPZA1,KPNA2,WBP11,SRFBP1,RPSA,MRPL47,RBM34,CAPZA2,SSBP1,MRPS9,SYNCRIP,RPL32,UBE2N,UBE2G2,ALYREF,DKC1,CDC5L,RPS16,NKAP,RPS27L,CDK12,LSM3,RPS2,RPL10A,SNRNP70,RPL24,EXOSC4,HNRNPH2,RPL27,HSPA5,UBE2K,RPS15,WDR3,MRPL41,MRPL10,SPTBN1,ZNF326,SEC61A1,CALML5,QSER1,PSMC5,ZNF655,RPS3,RPS17,TIA1,RPF2,RPL7A,CEP85,IGF2BP1,EIF3G,UBE2E3,RC3H2,TRAPPC14 |
| 7.426e-17 | -37.14 | ribosomal subunit | cellular component | GO:0044391 | 185 | 108 | 19108 | 5553 |
RPS28,RPL6,RPL8,RPS10,MRPS11,IMP3,RPS26,MRPS26,MRPL16,RPS7,RPL15,RPS20,RPL3,RPL22,MRPL13,RPL12,RPS16,RPS5,RPL7L1,RPL26,MRPL34,MRPL9,MRPS28,RPL17,RPL35A,MRPS25,RPLP2,RPL23A,RPL7,MRPS23,MRPS33,RPL13A,MRPL23,RPS17,RPL10L,RPL31,RPL27,RPL32,MRPS21,MRPL11,MRPL41,ZCCHC17,MRPS18B,RPLP1,RPL9,MRPL22,RPL19,MRPL24,RPS11,RPL26L1,MRPL51,RPS29,MRPS9,MRPL57,RPL10,RPS23,MRPS35,RPL29,MRPL10,FAU,RPL18,RPS2,RPLP0,CHCHD1,RPS14,RPSA,RPL4,RPL27A,RPL10A,RPS12,RPS27L,RPL7A,RPS15,RPL24,MRPL49,MRPL53,AURKAIP1,MRPS34,RPS3,RPL23,RPS24,RPS13,RBM3,RPL28,MRPL36,MRPL12,MRPL17,MRPL52,RPS4X,UBA52,MPV17L2,RPL37A,MRPL47,MRPS17,MRPL33,MRPS7,RPL35,MRPS16,EIF2D,MRPL20,RPL39,MRPL40,MRPL18,MRPS18A,RPS27A,RPS9,MRPL50,MRPS18C |
| 7.902e-17 | -37.08 | large_intestine-colon-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma-adenocarcinoma | 16405 | 4784 | 16828 | 4835 |
CACYBP,CTSK,CETN3,URM1,PWP2,MTAP,RAB3C,STX8,TOLLIP,BATF,DUSP1,TGFB1I1,NFYA,FAM200A,S100A10,CHST9,CPT2,ANP32B,DCAF8L2,NDNF,AP1G2,SETD4,OTUD6B,LCN6,COX7A1,FBXO9,CCND1,RPGRIP1L,OR2W1,TMED3,ACOT13,WFDC13,KLF10,AP3S2,MPHOSPH10,MRPL47,TMEM33,S100PBP,SPINK13,RHCG,ARHGAP21,SCG2,BMPR1A,FAF2,INPPL1,ING5,MIA2,BACH1,KIF2A,ID1,PTDSS1,ENTPD4,SLC35A2,ARMC8,NPTN,FCAR,CCDC42,CYC1,POU1F1,CRYBA2,DEGS1,PRKD3,CYP4F8,SLC5A6,DEK,NLGN2,SCAMP2,NUP107,OR52M1,SPEF1,CD164,PPIB,CDKN3,BPGM,RBCK1,MRPS25,NOP58,SPATS2L,AKR1A1,NFE2L1,FABP5,MRGPRX4,PGAP2,COA4,CTSD,TNFAIP3,ZBTB42,RAP2B,ABHD16B,DUOXA2,MTMR12,TRAF7,MMACHC,FYTTD1,IQSEC1,NOL4,SIRT7,RRAGA,ETV6,TAPBPL,H19,SPRED1,POLL,NONO,MAK16,ALDH1L1,TSSC4,OR2A2,EIF4EBP2,SOST,TCP11L1,ZNF805,SV2B,HPCA,SNAPC1,SNTA1,NDUFAF2,GPR37L1,GFOD1,SIVA1,FGF13,PRKX,PROX1,SYNGR1,LSM6,RTP4,ZMAT5,ENPEP,NAB1,VPS4A,SLPI,CERK,USP39,USP38,ZNF174,CWF19L1,CDK6,ESR2,DCAF5,ADCY3,FAM13B,SNRPD2,OAZ2,CLEC12B,SFTPD,CYP2D6,INTS12,SOCS2,RAB8B,CTNNB1,CXCL1,XPOT,PDIA3,FRA10AC1,NAA11,EIF1AD,NDUFB8,APH1A,ISYNA1,STX17,LEPR,WNT7A,RPRML,MSX2,KRR1,NLE1,SNAI3,CDC37L1,PELI3,STAMBPL1,SIPA1L1,PGBD2,HSPE1,CLDN14,ZKSCAN1,RPL37A,SERPINH1,DHX16,TRA2B,RAB4A,SOX21,HADHA,LEAP2,HSPB1,KCNA2,B4GALT6,LHFPL1,NUDT16,OR6M1,GXYLT1,CD3G,PAOX,BRMS1,CDKL2,KIF1C,CHRNA7,GAS8,OPA3,TAC1,NPVF,LMBR1L,AKR1C2,IGFBP4,IPP,NQO1,SPATA2L,TBCE,OXNAD1,HEXA,OCEL1,ADAT1,BRI3,RBM23,TMED1,NEDD8,CXCR1,FGF17,HBB,TRMT6,PTCRA,CCL21,NDUFA5,KCND2,IL34,DFFA,ST13,LPXN,RASGRP2,TIGD7,FBXO30,POLR2I,CD2,UCKL1,ACAA2,RAP1A,WWP2,RABAC1,SLC20A2,PCDHA5,NUBP2,PFDN6,LDHA,UBXN10,PRCC,GSK3A,THOC1,ABCC5,RANGRF,NUDT19,RC3H2,DNAL4,ATP2C1,FATE1,EXOC2,XPO1,THRAP3,EEF2,KIAA0040,SLC25A32,EFHC1,GJA10,TF,RNF103,CREB3,XPO5,SURF4,INTS10,APOBEC3C,GPR162,RNF187,SLC7A4,ZNF513,ZMYND11,GALE,EIF2B5,SH3GLB2,ENDOD1,ANKIB1,CIRBP,CXXC5,OSR2,SPOCK1,LASP1,PHKG1,MOB3C,UTS2R,NEK7,WBP2,GTF2A1,FUT8,CCL25,GNMT,AQP4,TXNIP,CREBL2,GLE1,EIF4EBP3,WDR37,ZSCAN1,OR51S1,SLC39A9,DHX9,FURIN,IL23A,PSMD6,TMX4,BUD31,SRP54,CAMK2G,PRMT2,CIB3,TACR3,GHITM,TUBG1,RPL15,CACNB4,CCDC47,SCFD1,TTC4,PYGM,OR4K1,SHC1,CAMK2N1,HCRT,FGFR1,CD200R1,KCNJ11,CRYGB,PPP3CA,FAM89B,RCVRN,PEX3,CCDC127,SBK2,SORD,SLC39A7,CCT5,ENPP4,PSMB5,MCOLN1,SMCP,FBXO32,ANAPC2,AGK,PRPF4,ARMCX5,ZNF593,IDH2,FKBP14,RAB18,IMPACT,AGER,CD58,PTPN1,HNRNPC,SETD5,NFIL3,TRIM37,HECW1,ZBTB38,SLC25A21,RBBP7,PGS1,RMND5B,ARMCX2,SIX5,TRIM21,ACTA2,ARFIP1,GALNT12,PPARG,SPR,RFX4,FRMD8,ADRB1,PKNOX1,ZDHHC14,RBM17,PCDHB8,HEY2,TRAPPC1,FAM199X,CLDN11,NIPA2,RABL2B,PAEP,LRP12,NPY2R,SPTAN1,SLC35E3,RNASET2,ATP6V1G1,MEST,FZD4,MTPN,WDR77,ZCCHC10,SYN3,GPBP1L1,TMEM213,MX2,AAMP,LYG2,MFSD6L,ZNF24,FBXO42,TMEM215,SERPINB10,TSEN54,PSME2,AZIN1,FGF1,HBE1,AZGP1,INO80C,ABCB1,LBH,JAK1,TBC1D10C,CCL19,MAGOH,NKX3-2,GTF2E2,MLF1,DEFB116,TNFAIP8L2,DHRS3,DNAL1,NDST1,KTI12,CDCA3,RAB3B,SMAP2,PIWIL4,CSNK2A1,KPNA1,GRSF1,RARRES2,KBTBD2,GSTO2,CTNNBIP1,GNG7,ATF4,P4HA2,JOSD1,SUPT7L,LSM3,AFTPH,OR4D9,KIT,RS1,CDC73,ZYX,UBAP1,LHX2,DYNC1I2,S100A6,CYP27A1,BTF3,MMP9,PGK1,VRK1,ROPN1B,MYH2,SNAP91,PACSIN3,ALKBH4,HEBP1,SLC7A9,TMIGD1,DNAJC5,ATP6V0E1,UBE2D3,CCT2,CHRM4,UBE2A,ARMCX1,NAIF1,TRIM23,NHP2,STRBP,ING1,P2RY1,OR8B8,IRF1,OR4D11,GAL3ST1,CASK,LTBR,PRPSAP1,ELMO1,TCP11L2,GRPEL1,FGFR1OP2,GABARAP,NCKAP1,NRP1,CDK5R1,GLUL,CNIH4,LMO4,CLU,ATPAF2,KIAA0232,CCR6,ZMYND19,SLAMF9,TAAR1,XAGE5,SEC14L1,ZNF319,ID4,ZNF397,APOBEC3A,GALNT4,IDH3B,CTNNBL1,GRM2,CYP11B1,PYDC2,SENP5,ADGB,JAKMIP1,GPAA1,TLR3,FAM8A1,NCR3,ITK,EIF4H,MYL12A,HSD11B1,CYP39A1,LRRC69,SWAP70,GNRH2,CHDH,MEF2A,IMMP2L,SLC35A1,DHRS4,HSBP1,ENY2,RAG1,SNAPIN,KLK3,SLC30A5,MRPL24,MRPL50,ZNF304,SLC38A9,OSM,IL15RA,PPP1R2,FAM78A,MIOS,RMND1,SOCS5,AK2,GALNT1,CCDC69,PSMA3,SPRN,TMEM156,GSTO1,MRPL13,MDM2,MGP,EHBP1,TOM1L2,UST,EXOC8,PFDN5,LYAR,NUDT3,B9D1,RND3,CNP,IL20RB,DKK3,SF3B4,DPP10,PRRC2A,RPS23,CRABP2,CDO1,ASMT,CCNI,PPIL4,RAB11A,TLR9,FIBIN,WDR38,SNX20,L1CAM,FGD2,APEH,AKT1,DLX1,COMTD1,FNDC8,ZNF207,TMEM219,ATP6V0B,EDF1,TMUB1,C1QC,TRIM3,POLR3H,SLC17A5,SLC25A31,ZNF671,LYPLA1,LIG3,RPS14,UGCG,MEAF6,ARHGAP1,DOK4,KLK9,PLA2G5,KLHDC8B,RNF141,TRIM32,PDIA6,UBR7,SDR42E1,SNRNP27,PRIM2,CD99L2,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,E2F6,GFM2,MRPL23,GDI2,POPDC2,GPX6,TGIF2,GREM2,PRPF19,CREBBP,LDOC1,GPAM,PDCD4,RDH10,HTR1F,OR4Q3,TRIM54,RPLP2,FAM98A,ACBD7,CDC42SE2,TMEM184B,KDM4B,ZNF287,ACAT1,OAS1,NKIRAS1,GIT2,SDF2L1,RUVBL1,GTF2B,CXCL3,RAB3D,CLDN4,SLC13A5,LAMB2,SMU1,SLC35D1,COL1A2,RMI2,SAT1,R3HCC1,CSGALNACT1,EDEM1,GNG2,VAMP5,METTL14,PTS,TOR2A,AMIGO1,JPH4,MBL2,MAP3K11,GTF2H2,ANKRA2,ADIPOQ,ALKBH5,ERH,CRTAP,LCP2,UHMK1,IK,METTL2A,CLDN1,ABHD6,TFCP2,NDUFAF4,CRYBB2,AKAP14,CCNB1,CTDSP1,FAM162A,FUNDC2,MRPS23,ZNF862,SYP,ATG4A,CSRNP1,CDKN2AIP,RGS7BP,SFRP4,RER1,FCN2,ISG20L2,GPHN,POLE4,HSP90AB1,ARMC7,ATAT1,CIDEB,IPO8,TMSB10,CCR2,ZC3H7A,AIF1L,ZBTB5,DSTYK,TMEM123,BCS1L,SNX17,APOO,GPR137,NRSN2,TMEM144,TOP1,SRRM5,OPRK1,GCNT3,PGPEP1,F9,NKX3-1,CYP2C18,NDUFS8,ZNF740,MYO6,SEC61B,TEX30,GPR65,TOM1,BCL7B,EIF2B3,DNAJC22,HTR5A,TMX3,PAPSS2,TCF23,CHGA,GBE1,ADO,CALHM2,GMPPB,LMNB1,BECN1,TES,FAM219B,CCDC25,OSTM1,CHMP2A,EMP3,HSPA8,MSMP,SLC19A2,CBR4,VMP1,B9D2,EWSR1,TMEM204,GPX3,PROS1,ABHD14B,MRPS16,EED,ZNF592,MTRF1,ELP3,YAF2,CIB2,DTYMK,TGFB3,MRFAP1L1,TRIM24,ACSL4,RINT1,OR10G9,TSPAN5,BZW2,SPECC1L,NAT2,KHDC1,CD274,EIF3K,B3GALNT1,CREB3L4,ZBTB17,BCAP29,FABP7,SSU72,AKAP12,IGBP1,RAB40AL,DDX39A,SNAPC3,SNCG,BLOC1S2,LHFPL4,CALHM3,CDKN2C,COX4I2,TMSB4X,EIF4E,TRIM5,TSPO2,OLFML3,GOLGA7B,EFNB1,RNF113A,THTPA,PREPL,SH3GLB1,TFE3,DEFB114,MT1M,IFNA10,PELP1,ITGA6,CSNK1A1,COMMD8,NTN4,RTKN,HOXD12,PHYH,FUT9,UBE2V2,IL10,RPLP0,DERL1,IL18,ST3GAL1,SOX2,CSNK1A1L,ERV3-1,STOX2,PCMTD2,KLC2,STXBP1,PAX9,MTHFD2L,IRF3,CD36,DPEP1,UQCRH,PRKAB1,RAC2,NDUFB4,STK24,LCA5,PYROXD2,MRPS21,LRP6,TAS2R40,PARP11,FAM163B,SLC32A1,ST3GAL5,POR,CEP97,ZNF501,IFRD2,MBD5,KCNMA1,BCL10,NOS1AP,ADPRH,PDHA1,NME1,DUSP19,RGS2,STMN2,CNNM4,NR1I2,DPY30,NPR2,CDK4,KCNK13,TRAF2,RBM7,BRCA1,ABHD4,PCDHB1,STAU1,STOML3,TSN,SLC41A3,SERINC3,TMED7,RNASEH1,DNAJC3,FKTN,KLK6,PIWIL2,SOS2,AKIP1,GYS1,SLC23A2,ROGDI,PGM2L1,RBFOX2,FOXN2,GK2,CDKN1A,SLITRK2,STX18,ELSPBP1,ORAI3,SDHAF2,CLIC2,MED11,PPFIA3,OTUD7B,AMY2B,NDE1,RBMX2,HMBS,CD2BP2,TDRD7,CCDC65,LDHAL6B,SELENOV,UBE2D1,LY6G5C,SLC4A8,SNIP1,FAM168A,ACTL6B,RGS5,INHA,RPAP2,OR5L1,RAB1B,HRH3,ZBTB45,ABHD13,ZCCHC9,SLC43A2,TMEM91,B3GNT2,HIGD2A,TEX12,TOP3B,LRRC24,GRIA2,FLYWCH2,MRGPRX2,DDX4,KLK5,LIX1,CAB39,TMEM14A,TCEAL7,GDE1,PCGF3,GPX5,OR14J1,CDH8,CPSF2,MYEF2,PNPLA8,TAF5L,MOV10,UQCR11,GLT8D1,NGB,CD226,SACM1L,VPS33A,CRBN,PDYN,ZFP1,B4GALT3,BEND5,SNRPA,CMPK1,TRAPPC6B,VAMP2,CCNF,CTNNA1,RAB2A,WDR44,GPIHBP1,PHYHIP,FN3KRP,WIF1,DYRK1B,OR10G7,ISG15,SNX24,ACADSB,STAT6,EZH2,ARCN1,FGFBP2,INPP4A,KCNIP3,AMT,RAB9B,TIMP1,DERL2,TXNL1,ELMOD1,MLF2,PLEKHJ1,RPL23A,LYNX1,TMEM59,IL6ST,EIF4B,PPP2R1A,MRTO4,PTHLH,SLC25A4,SMAD3,TIMM10,STK38,RAB5C,PNP,PCDH19,WEE2,AP1AR,SMN1,FOLR1,SLC6A11,RAB37,CSTF2T,PSRC1,IFI35,FBXO25,C1QL1,CAV2,WWP1,RHOJ,CBLN4,S100A8,HIRA,CD47,TMEM50B,JUN,IFNG,CCR3,OGG1,ZNF687,OPHN1,SUMO3,PTGER1,SFT2D2,CMAS,RAB23,DNAJC8,PPDPF,TNFSF18,FAM107A,RNF167,RAB33A,CRYGD,TNRC6C,SPTBN1,CHI3L1,RNASEL,EIF3J,FERMT2,TOMM40L,GIMAP2,GNPNAT1,UTP23,HNRNPK,PAFAH1B3,PRKAG1,NFKB1,ACAP2,MAFG,SCD5,LHFPL2,CLDN22,EGLN3,FOS,DYRK2,POMP,RPL26,OS9,RIOK2,MRPS28,OAT,NAA60,CCL8,RFTN2,TPPP,CAPZA2,RB1CC1,SLC35E1,YPEL5,PPID,RCBTB1,GGCT,ATP6V1C1,TAPBP,HNRNPA2B1,MAPK1IP1L,FANCG,OR2A25,STX6,PLA2G15,NAPG,RNF122,KIAA0408,BICD2,SERPINA5,CREB1,FMO2,TMEM177,RBM12,RPP25,RAN,SQSTM1,GLIPR1,POLR3B,HAND2,PGR,BRD9,LCN9,CXCR4,HSPA14,NPY5R,CDH13,KIAA1191,CCL17,PAFAH1B2,OR2H2,DLG4,GTF2F2,KCNH1,SLC7A14,DDX42,PPP1R16A,MT2A,ATP1A2,PXMP2,CYB561D2,GMPPA,TUSC3,SPRR1B,RPL6,CLDN8,ADAMTS1,CXCL14,BNIP3L,TRAM1L1,SESN2,PLAGL1,PAPOLB,RFXANK,KLHL15,GCA,RABL3,UPF3B,ISCA2,ZNF576,FCHO2,CHST1,MPV17,EHD1,PPP1CB,TRAM2,KCNK10,SLCO1A2,TMCC2,SELENOS,ZNF609,KRT7,PLEKHA8,GJB2,WDR3,MANSC1,SRP14,NUS1,TMEM106C,ACTR2,CRYBB3,OR4F6,PTRH2,FOXS1,TAS2R5,TMEM203,APLN,SYNJ2BP,ACP6,TMEM164,MAPRE1,NRN1,CTXN1,MUL1,SMG9,GNG10,SEC22C,ZFAND2A,MME,METAP2,FKRP,LPAR2,USP15,ELMOD2,OR10A4,CNRIP1,APOBEC3G,GNG12,PABPC1,NTRK2,RNF144B,DNAJB9,ARG2,GNAZ,GLRX5,RTN4,GAMT,TOMM6,ISX,SIAE,CLDN3,ADAM21,INO80E,DEPDC1B,PTEN,RLIM,UCN,CRLF3,PTAR1,MGAT5B,UAP1,THAP7,TXNDC12,RWDD3,CENPW,SDHB,GFPT1,ATG4C,FRRS1,SNRNP48,SIT1,FDFT1,NEGR1,MOXD1,CCDC160,RPA3,EPHX1,CKS2,RORB,ABHD5,CXCL13,PPFIA2,CNDP2,FBXW11,CINP,IL1A,BCL7C,OR4D6,THBD,HTRA2,JAGN1,SNAP29,NDUFAB1,TYW5,RPL27A,NUDT12,CBLN2,METTL15,BABAM1,NEUROD2,PGRMC1,DHX38,GPR171,COX20,PTK7,USP8,TMEM147,LGALS8,COX8A,NXT2,HNRNPA0,CHST2,RHOBTB1,FZD3,CD247,IKZF5,SPRED2,OPRM1,CDAN1,PDE1B,PIK3R2,UBE2K,PCNA,DDX23,TMEM126B,NDUFS6,CTSC,PCYOX1L,CREG2,AGPAT5,PLD3,LRRC3,HR,DNTTIP1,FBXO44,DKC1,ARPC3,LARP4B,OR2Y1,STX11,PMP22,SERPINA1,MRPL11,SCLT1,LRRTM3,DAAM1,HSPA13,LSM10,ANKRD34B,UBB,PPP2R5E,SH2D1A,SLC11A2,LMAN1,NPSR1,RHEB,FBXL14,OVOL1,DHX15,RPS7,PSMD4,NPPC,RELL2,TRIM15,GPX1,RAB27A,GRAP2,SLC6A6,CCDC134,TCF19,SLC30A7,OCRL,MAT2B,ZNF664,MLC1,DDX46,PDHB,TSPAN18,RPS6KA4,GANAB,BBS5,XCL1,IMP3,IRAK4,UBL3,KCNJ3,COMMD6,B3GALT1,TMEM30A,AFAP1L2,GNPDA1,SNX22,SFXN2,CST11,FASTKD5,CYP21A2,GNAO1,NCDN,TMEM117,TMEM170B,NDUFB6,MRPL34,GLRX,TOR3A,UBA3,CBLL1,TAGLN3,STAT2,SAV1,PCDH17,EPCAM,SRSF7,PRR3,IL22,CSGALNACT2,CSTF3,HENMT1,RPL7L1,REEP3,ST6GAL1,TMEM179B,TOMM22,BFAR,ORC5,ILF2,OXSR1,ZNF365,BAG3,TOM1L1,KDELR1,KRAS,RPS16,RBM22,RRM1,CNTN2,ASNSD1,DKK1,HERC4,NR2F6,PSMB1,ZMYM3,CRIP1,CFC1,CHPF2,NDUFAF3,IER2,COMMD3,BMPR2,PPP1R1B,RND2,OLFM3,SCG3,CCS,RASD1,SCGB1D1,ILDR1,NLRP3,METTL21A,G3BP1,CHAC2,POP5,PSORS1C2,FGFBP1,MFSD5,MRPL18,HINT2,TMEM101,OR13C8,NUF2,SLC16A1,RPS27A,PCDHB13,TPD52,ELOVL7,DBT,RAPGEF5,DAPK3,DSTN,MRGPRX3,MTA2,CCDC86,SUFU,FBXL19,LAPTM4A,CHCHD4,CHIC2,PGGT1B,SLC38A7,KCNC1,OXTR,SCNM1,MCM4,FAM177A1,DCTD,THOC2,STARD4,NR2E1,DROSHA,FLOT1,ORC6,KLHL22,UBP1,MAVS,SLCO2B1,CX3CR1,IGF1R,CHMP4C,CEP19,SOX14,PDAP1,CDCA7L,SS18,MRPL22,CD1C,UMPS,RAB19,FCGR2B,NUDT7,IFIH1,BIRC2,MTM1,HOXC4,UPK1A,RFXAP,EPS8,CER1,POLR1B,CHCHD6,SIAH2,CCNY,CHKB,PKP4,GPR176,CLDN12,ELF5,VGLL4,DNAJC19,SCML2,FCGR1A,ERAS,GSTM5,ZNF326,PLEKHO1,MYBL2,OTOS,CNOT2,CRHBP,ODAM,KLF1,VDAC1,CLPB,FEN1,PRKACB,ASB7,APOBEC3H,LANCL2,GLRX2,ADD1,SEPHS2,CBR3,CLEC2B,JKAMP,TMEM237,LAMP2,FAM43A,NLRP9,TMEM45A,RNASE1,CGB8,PPM1K,OR8B12,CCL2,GSTP1,LLPH,IFI6,AR,SNRPB,TPM3,EFNA3,SOSTDC1,ELOVL1,MORC2,SSR2,GPX7,CHRNB2,RIT1,OR10P1,PTPN4,HSD17B6,TMEM167B,APOBEC3F,MAP2K1,PLCB2,FEZ1,PRDM4,OTX2,EIF4A2,MAGEH1,LRRC3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,TOX4,KLRC2,CENPL,TRIM26,NUCKS1,IER3,MRPL9,UBE2G2,FEM1B,MRPS17,SGIP1,MECR,UPRT,SUPT3H,FXN,PELO,GMPS,TTC9C,GORASP2,THUMPD1,SNAP25,RXRG,IGF1,CCR7,GRIK1,DLGAP4,CMA1,SNRPE,RRAGB,GALNT2,ANXA4,RASL12,IL18BP,PIH1D1,KCTD3,RDH11,NKAP,LBX1,ELFN2,RP9,GALC,HAUS2,OR5M9,GNGT2,CNPY1,SSPN,LRRC8A,MBD3,CDC23,ELFN1,DMPK,MPG,TANK,BRAP,SYNGR3,HSPD1,EIF1AX,RNASEH2C,PARD6A,TCEA2,LRRC28,PNPLA4,PIAS1,NUPR1,TMEM115,NPC2,CAP2,EXOC3,SAP18,TMEM81,DDR1,SLC22A6,TIA1,SPG21,S100A11,ZNF622,ATG9A,TGFB2,RBMS2,SLC25A27,VPS54,GLOD4,PIGA,BOLL,MX1,THOC3,BTG3,DPEP3,TMEM183A,GRPR,IGFBP3,GADD45A,OR1M1,CD9,RUSC2,BTG2,ITGB8,CCDC3,VAV2,NUFIP2,CMC1,HINFP,GNB3,TMEM229B,TRIM44,PAIP2B,LRP10,NR1I3,FHL3,FAM20B,TICAM2,GPRASP2,PQBP1,PPWD1,NRM,MPV17L2,CRYBA1,WDR45,THAP8,HSPB6,HSPA5,SERTAD2,GNA11,GK5,SSNA1,GLCE,SLC25A24,PDCL,SUPT5H,STAR,RPL10,TRIP4,CD209,ST3GAL2,TAS2R7,P2RY4,FBXW4,IL2RB,PTGFR,IP6K1,TEX261,OR4D5,ZDHHC16,RAP2A,MSH6,MDFI,PPP1R11,PSMD3,DTWD2,GPR160,POLR1D,CYP4V2,APLNR,CNPY3,SRI,NCAPG2,OR51E2,GP9,KRTAP8-1,POLE3,FAM133B,RNF10,PYCR2,CDIPT,TNFSF8,ZNF428,PDE2A,RAB6A,CTTNBP2,RGN,FKBPL,CDK7,SIN3A,SCAND1,PSMD7,PLAC1,CRY1,SLC6A2,TNFSF15,AIP,CD40,TLR8,PMPCA,NOG,MED22,ARFGEF1,TAB2,SRPK2,PIWIL1,TRAF3IP3,RGP1,CCDC90B,RPA2,TMEM107,PRSS8,LDB2,YPEL4,GADD45G,RNASE9,OR4A47,DCTPP1,TMEM100,EID2B,PRCP,CD34,FBXL4,UNC79,THAP1,CPXM1,LRRN4CL,SSBP2,PDCD10,GDAP1L1,RPL31,WTAP,ZSWIM7,BAD,TSPAN3,MGST3,OLA1,PRPS1,HAS3,CRHR1,AKR1E2,UQCRC1,NOC4L,SKAP2,CLK1,RASSF4,SERPINA3,KCTD20,RSL24D1,TRAF1,ZMAT3,BRS3,C9orf72,NAA30,NETO1,PTGER2,CDR2,IRF9,HSD17B8,LSM4,CGRRF1,DDX39B,HERC3,PSMB4,DOK6,SEMA3C,CD200,TMEM220,ST8SIA4,USE1,TMEM168,NCK1,SIAH1,LRP3,STRADB,SLC15A1,KCTD16,ZBTB6,PLEKHF1,AHSA1,HNRNPAB,GPR78,ZNF655,TRIM62,TEX19,CDKN1B,COX7B2,CMBL,HMGN4,SCHIP1,TAF9,MEA1,PHOSPHO2,SCG5,TRAPPC2L,TMEM198,RFX5,NMRAL1,MAT2A,OR6C4,SNX11,RPLP1,TIMMDC1,MT1X,UBE2V1,SERPINB9,PDE6A,HELT,TRNP1,IMP4,HOXB8,SSH3,SEC61G,EMX2,CENPM,GFM1,PRM1,GAL3ST4,ADIPOR1,SLC7A11,RETSAT,POPDC3,FZD6,MET,RANBP1,ATF3,RBM5,CTLA4,PDLIM3,PRSS37,MAP1LC3B,ACSS2,IFRD1,DEFB1,RHOU,B3GALT4,DLG3,RPL22,CEBPE,TMEM176B,ESYT1,F2,ARL5B,CAMKV,VPS26B,YKT6,ANKH,AANAT,SAP30BP,HAPLN2,EDC3,GMDS,WNT2,LDB1,CSRNP3,NRGN,TRAPPC3,MFSD3,BIRC5,CTDSPL2,ARL6IP5,CEP70,ABHD2,ANKRD46,SNRPA1,SNN,PSMG2,DTL,KDM1A,NDFIP1,CCDC22,TBCEL,PRSS35,FKBP2,UNC45A,NUDT1,RALB,ISG20,TMEM87A,CYP26A1,GMNN,GPR34,TBC1D1,TIMM13,RPF2,XBP1,PDLIM4,THG1L,ERCC3,GABBR1,OSBPL8,CEP57L1,ARHGAP19,TACR1,DIS3L,CA14,EMILIN3,MTA3,DRD3,CEACAM5,NAP1L3,NACC2,CHRM5,SEMA7A,NAP1L5,MED4,ZCRB1,APOC2,CYB5B,OR9I1,TRMT5,BCKDK,LIPT2,HPCAL1,MRGPRX1,RACGAP1,CORO1C,RRP7A,CCDC126,RBM3,STT3A,MAGEA4,RPSA,PIK3CG,NPBWR1,ERLIN2,UBE2S,HYAL2,RHOH,ARHGAP15,GPR75,SETD3,TMEM126A,FOSL2,GNPAT,ACP2,ACTL6A,ZNF436,WBP11,DIO2,EGR1,STARD7,ZNF343,CHTOP,SYPL1,SCN2B,ANKRD10,TEF,TMEM231,TCTA,PCP2,SOD2,ADD2,MLN,KLF12,IAH1,WDR12,PDCD1LG2,RAB1A,GLO1,AMELX,VSTM4,NEU1,CNOT8,PELI1,PIGK,FBXO31,VSTM2L,ZDHHC17,MAP1B,PSMG4,AQP3,RIMKLB,ETFA,APMAP,PRELID1,ECD,CD59,AKT2,ITPRIPL2,JMJD8,GAB1,PSMC5,PRSS1,APEX1,SOX9,CHST10,KCNG3,GPM6A,COTL1,PNPO,OR2D3,LCN1,RFC4,TLR5,HIGD1C,TICAM1,HS3ST3A1,DCAF16,SRD5A3,CLRN2,REG1A,PLCXD3,C1QL2,TSPYL4,DNM2,OR4K13,GTF3C4,MMP20,HTR2A,SMARCB1,STAP1,ACTR1B,SUGP1,ABCC2,STARD5,FMO1,DEXI,ALG5,TP53TG5,DIRAS3,SIGLEC5,HDAC11,ATG16L1,TTLL10,SKP1,CHCHD2,GCHFR,GJB1,KRT8,PRELP,CSF2,PCYT1B,LCP1,AGGF1,HNRNPH3,IZUMO2,TPST1,ZNF200,COPE,RBM41,RWDD1,SLC25A3,HCFC2,PABPC5,IRF2BPL,PRKCB,LSM5,DCTN3,SUV39H1,RGL1,RPL4,SEC14L5,HBP1,SPAG11B,DYNLRB2,CKS1B,CRYBA4,RAB32,PITPNA,FOXC2,CRYZ,BLVRA,APOBEC3B,FAM193B,PCBP4,MLH3,HS3ST1,TULP3,SPDYE4,OR4M1,BMPR1B,RANBP10,SRM,MED27,ADH1B,MPP1,BARX2,PSMD1,SART3,PTPRZ1,IFI16,VPS39,SUPT4H1,FAM174A,MYLIP,ATG3,CFTR,INA,OR5AN1,CLPX,CLP1,VWF,GPR37,ESD,CDKN2D,ATP6V1D,ART5,TMEM39A,CDK17,CHMP1B,PSMB10,MARCKSL1,SLA2,SDR16C5,IFNAR1,TNPO2,PYCR1,THOC6,HINT1,RXFP2,RAB9A,RPAP3,CCL11,OPRL1,HSDL2,LYPLAL1,DYNLL1,NUP62,RNF139,SMG5,ABCF1,DUS4L,PLP2,FMOD,ADRB3,SPATA4,CMTM7,SLC7A1,CA12,TBC1D16,IRF4,CSRP1,LEMD3,ARL6,RAB11B,STX5,CCND3,CYP4F22,ARFGAP1,PIGC,STK38L,MVD,CDC26,SHC3,PREP,SRP72,DDIT3,SLITRK1,EDEM2,FIS1,CACNB2,HCFC1R1,RPL28,PGAP3,LCN15,MB21D2,MCCD1,SLC39A10,HM13,BCAS4,TCEA1,VCPIP1,OAZ3,WBP1L,ALCAM,JUNB,CCL24,SNRPD1,LIPA,PTPN5,UFSP1,TIMM17A,RELL1,SMAD9,RNF182,TNIK,S100B,LRFN3,OR4B1,PDE6D,OR5K1,PDZK1IP1,UBE3A,SMARCE1,PITHD1,LEP,SH3BP4,ASPM,EFNA5,CBFB,ZC3H14,TADA1,CETN2,ZC4H2,IFNA13,CACNG3,RIT2,DOK5,SEC22A,MAP2K3,DCTN4,RPL7A,CXXC1,FIG4,LSM12,RCHY1,FAM20C,SPHK2,FGR,MRPL12,ARF6,B3GALT2,PPT1,ZDHHC24,FHIT,ARL11,KRTAP4-1,MAP3K3,RNF7,MRPL16,TECR,EZH1,ARGLU1,PNRC1,LAMTOR2,SLC41A1,MFAP1,MXD1,UCP2,TMEM106B,UBE2I,SPCS1,TDP1,MID1IP1,GLIPR2,SERINC1,SNRNP70,PLEKHF2,DICER1,MAGEB1,SLC6A7,ZNF362,POU5F1,MSN,HBM,FGF16,SAP30,RNASE4,DDIT4L,SLITRK5,IL21,RPL19,KIAA1958,ZNF345,EID2,MAEA,FOXD3,FBLN5,LYRM2,CXCL10,ASCC1,CDH7,SLC37A4,SMUG1,SVIP,DUSP18,UBXN2B,ZNF770,TPD52L1,TTR,SEC61A1,GAD2,RSBN1L,METTL18,BGLAP,COX7B,CDC42SE1,FAM83A,RHOG,NOL12,SDHC,RGS1,ASB11,BTBD10,EMILIN1,PRDX3,PDCD5,LRRC14,ZBTB26,TUBA1B,CKB,THAP6,MRPS26,PHF7,HMGB1,GNG11,ARF1,ZMYM6,EIF2B2,ZHX1,SERTAD1,KCNIP2,FA2H,ERRFI1,HNMT,DPAGT1,CTSA,PPIL3,ZCCHC7,PHTF2,LPCAT3,GPR83 |
| 7.945e-17 | -37.07 | regulation of localization | biological process | GO:0032879 | 2028 | 761 | 18204 | 5365 |
CSK,RSAD2,ERP29,PCDH17,BGLAP,MIR107,PEA15,CXCL9,MYO6,DPP10,IL12B,MX2,MIR185,RNASEL,FGR,VEGFC,GPC4,SNAP91,PPARA,FLOT1,MIR186,PRL,KCNA2,TRIM34,VDAC1,TRPC1,DMAP1,CPLX3,MIR129-1,CD36,BAP1,SNAPIN,MIR210,LGI3,MIR33B,FERRY3,SIN3A,IFI27,CHMP2A,LYAR,LILRA2,HADH,MIR21,CACNG3,INHA,RTN4,GNAZ,ILDR1,PCK2,NOS1AP,JAK1,RGCC,CREBL2,NGDN,SLC1A2,HYAL2,CTNNB1,SLC1A1,RALA,PDCD10,TTL,EP300,BOK,PACSIN3,CAMK2G,MIR92B,DRD3,LZTFL1,GRB10,SMAD4,SELENOS,UBE2G2,P2RY4,LMNA,DPH3,TBC1D4,CRY1,GSK3A,RAMP3,RAB27A,SLC4A8,BAD,STXBP1,JAK2,PTEN,APOC4,BCL2L1,ATP8A1,STX7,ATP5IF1,PLAA,NUP153,MSN,CRKL,CARTPT,SLC8A1,RIC3,SNX12,RIOK2,GNAI2,CD14,MIR206,OAZ3,MEF2A,RAB8B,MIR873,DYNLL1,PGRMC1,MIR34B,BIRC5,IFNG,SLC25A23,PSEN2,PLCB2,CBLL1,PHB2,SQSTM1,HNRNPK,LEP,TRIM21,CD200,ATF4,TM9SF4,MTMR2,NRDE2,KCNJ11,PPID,ANGPT1,DAG1,STAC3,SRC,CALY,SLC38A1,UBASH3B,LYPLA1,BNIP3L,NFE2L2,SNX17,COX17,MECP2,UBL5,BORCS5,TOMM7,CCT5,MIR153-1,SNCG,LYSET,GSTO1,MKLN1,DNAJC5,RAP1A,CCN3,RHBDD3,KLRC2,CRHBP,TFRC,SELENOK,CLTRN,SLC7A11,STC1,CD63,MIR24-1,ISCU,SMAD3,KCNJ10,FCGR2B,NKX3-1,CCDC32,STAP1,MIR205,RINT1,CLU,RALB,NFKB1,KCNJ8,TERT,IL15RA,TESK1,FGF13,GNA11,SRI,PLP1,P3H1,UBXN2B,HCLS1,SYBU,PML,SFTPD,CCL19,C2CD2L,GRM2,TMEM59,ADGRE2,PLN,CD2AP,CD38,LAMTOR1,KCNJ3,NLGN2,IER3,CREB1,ATP1B3,PTGES,DAPK1,FITM2,SLC43A2,CASK,HCRT,WWP2,PREPL,THOC2,RIMS3,BTF3,HSP90AA1,FGF12,SNAP25,GDI2,CDK5R1,KCNJ2,PDCD5,APLN,CDK1,HTR2A,INPP5K,HSP90AB1,NDUFA4,CNPY4,FKBP1B,CAV3,MEF2C,MCOLN1,CAV1,ACHE,MEPCE,USP8,HTR1A,ARL6IP5,PSEN1,LILRB4,CD4,AP2A1,CNKSR3,RBM22,MIR208A,PKIG,SLC38A3,SNX3,FGF10,IL2RG,TF,RIMS4,SVIP,MIR144,TGFB2,CHP1,IL1A,FCN2,SNX33,CDH13,VPS4B,GREM1,ADTRP,CREBBP,WASL,GCLC,GSTM2,PRKCB,CHGA,MCHR1,RAP1B,CRHR1,SUMO1,CD151,RER1,EDEM1,NLRP6,MMD,MIR200C,CCT2,ATP2B4,TTC8,CHRM1,RIT2,MACROH2A1,ACTN4,ATP1B1,SLC35F6,ATP1A2,PICALM,CCL21,MIR20A,TRIM22,CTNNA1,CLEC7A,SCN1B,IL13,UBE2D3,VPS4A,MIR34A,LPAR1,MIR133B,TMEM30A,ARF1,HUWE1,PTPN11,NETO1,TOMM70,LRRC8A,TRIM27,DDIT3,GHITM,RAC2,FGFR1,P2RY1,PLPP4,ICA1,SCAMP5,SGIP1,ADORA1,ADORA3,OSBPL8,CHRNB2,SLC6A4,EPO,CHCHD4,CLSTN3,PPARG,SFRP4,DCP2,TSPO,JUP,SESN2,MIR145,RAB11A,TRIM6,H1-1,VAMP7,ADIPOQ,DDRGK1,ROCK2,CACNB3,S100A10,CXCR4,CAB39,TRIM46,STXBP6,PYCARD,HRAS,ZDHHC8,ABHD17A,MBL2,MIR495,HMGB1,STX1A,RGS2,EPHA2,VPS28,ASIC2,MIR424,ATAD1,VAMP2,CXCL10,ATG3,JPH4,SPHK2,SH3GLB1,NETO2,EDEM2,CCR2,F2,CAPN1,PLSCR1,UFM1,SCN2B,CFTR,LMAN1,TBC1D5,AZIN2,EFCAB7,IL6,AHCYL1,GP9,BAX,MIEF1,GNAO1,MMP9,ACAA2,PTP4A3,GPM6B,LRRTM1,MIR223,ACVR1C,ACSL4,RAB23,MMP14,FCER1G,CLIP3,HAX1,OXSR1,PRNP,BVES,MIR130B,SNTA1,TMBIM1,AKT2,PPP1R12A,CA2,UHMK1,VPS18,UCN,TP53INP2,NUS1,EDNRA,SAR1B,SELENON,EHD4,DNAJB6,SYT4,SFN,LPCAT3,MLLT6,HDAC3,PLCB1,TLR9,KCNIP3,TNFRSF1B,MIR148A,PPP2R5A,BAK1,TXN,MAP1B,TCAF2,GH1,RAB3D,OXTR,RETN,CXCL11,INPP5E,NPVF,ENY2,UCP2,IGF1,NFKBIA,DKC1,TAX1BP3,CALR,PIP4P2,SIRT7,ABCB1,AGR2,SLC25A31,GPC1,ITGA2,PFKFB2,B9D1,CCT7,VSTM2A,SLC6A1,ARFGAP1,WNT7A,PPP3CA,IL1B,TGFB3,AKT1,PRKCE,CPLX2,CDK5RAP3,MIR10B,PARL,LCP1,MIR448,TSG101,KCNS1,PPP3R2,PCSK9,NRP1,PLA2G5,NR1H2,CNR1,SOD1,AR,XBP1,PID1,ANP32B,NEO1,SURF4,SESTD1,STX10,ROCK1,P2RY12,MIR143,PIK3CA,TIAM1,CD47,CACNB2,NLGN1,FASLG,VAC14,PDE4B,PIK3CG,THY1,STX18,WRAP53,UQCC2,SLC38A2,VEGFA,VRK1,PRRT1,FXYD6,NF2,IL15,FABP5,AP2S1,PRELID1,FGF23,STIM1,TCP1,OPRK1,CAMK1,BET1L,STOM,PIK3R2,RAN,PIK3R1,AMIGO1,OSM,YWHAZ,CPLX1,MIR301B,ASIC1,GLUL,VMP1,UBE2L3,YES1,RAB33B,LACRT,APBB3,SPTBN1,PRSS8,XPO1,SCN3B,PRR5L,MIR208B,S100A8,TESC,HDAC6,FBXW7,TRIM5,SELENOT,STK11,HILPDA,SYK,TMBIM6,RAB14,SCG5,DERL2,CACNB4,CHRM3,DRD1,TMEM231,SYNGR3,SYP,CCL2,MAP2K6,NPSR1,NHERF1,NUP62,DNAJC1,PICK1,AKAP8L,VAMP3,PIAS1,YIPF5,TMEM97,VIP,PPIF,FEZ1,STX6,DMPK,SLC12A2,G6PD,TLR2,MIR183,RAB5A,ARFIP1,SFRP1,FERMT2,CSNK1E,CRYAB,PPIA,CDC42,CCL5,KCNB1,KCNC1,UBAC2,TRIM68,IL2RB,RAB4A,STX8,PARD6A,OPRM1,MIF,CCL3,RAB9A,RASL10B,YWHAH,LILRB1,REN,IL12A,SWAP70,AP2M1,EFNA5,RUVBL2,GPR35,VTI1B,CLIC2,KCNAB1,TYROBP,FURIN,MAVS,MIR146A,CD81,ATP2C1,ARPP19,MRLN,OPHN1,HTRA2,IL4,NPTN,TACR1,RAB29,OTUD7B,JAGN1,MIR9-1,TRIM8,KCNMB1,FRRS1L,PPFIA2,OSBP,MIR192,CCR7,ADRB2,REEP6,C9orf72,RAB3B,MIR30D,GAS8,SPP1,VAMP8,DKK1,DHX9,MAP2K1,PPP1CC,CCR1,HGS,KCNIP2,FCGR1A,CTTNBP2NL,FKBP1A,OR51E2,NHP2,KDM1A,SLMAP,TRIM29,OS9,FIS1,BECN1,RAB3A,DLG1,GHRL,AZIN1,CBL,NDFIP1,BAG3,ERO1A,CCR5,SYNJ2BP,MIR1-1,TNFAIP6,HPCA,OAZ1,EHD1,LEPR,NCBP2,MDM2,SDC4,SDCBP,RCVRN,VCPIP1,SUMO3,CRBN,TMEM14A,HOMER1,APLNR,TLR4,DLG4,TMEM38B,GABBR1,ITGAV,ARHGAP1,HSPA8,PTPN1,B2M,C1QTNF1,LGALS3,RNF139,APOC2,SCFD1,MIR212,SV2B,SLC16A1,UFL1,CD247,MLC1,SUFU,HOMER3,RHOG,ATP1A1,FCGR2A,AVPR1B,SLC25A4,ERLEC1,RUVBL1,LRRTM2,TNF,ACTB,MUL1,PPT1,XCL1,NDUFAF2,CX3CL1,ABHD5,OAZ2,FITM1,HECW1,PKIA,CCT8,RANGRF,ORMDL3,NSFL1C,GOLPH3L,CDK5,RAB11B,CXCL12,RHOU,HFE,CTDSPL2,RAB31,WDR44,NPY5R,SLC25A5,TMSB4X,LRAT,CDK9,SLC25A27,ARF6,CLDN3,CTSD,MIR17,GJA1,CNTN1 |
| 8.352e-17 | -37.02 | Translation | REACTOME pathways | R-HSA-72766 | 162 | 102 | 10285 | 3229 |
SEC61A2,SEC61B,RPL19,RPL26L1,PABPC1,EIF2B3,SSR3,EIF3D,RPL31,RPL12,SPCS1,TRMT112,EIF3J,RPS9,SRPRB,RPS11,RPS2,RPS10,RPS27L,RPL23,RPS15,RPS14,SSR2,RPL7A,EIF3K,RPL24,EEF1A1,EIF4B,SRPRA,RPL3,FAU,RPL32,EIF5B,EIF4A2,RPSA,RPL27A,EIF4H,TRAM1,SRP54,RPLP0,RPS4X,RPS17,EIF2B2,EEF1G,RPS26,RPL8,RPLP2,EIF4E,RPL35,RPL10,RPL17,RPS3,EIF3G,EIF2S2,RPL22,EIF3E,RPL9,RPL18,EIF2B5,RPL7,UBA52,RPL37A,RPS23,RPS12,RPL27,RPL4,RPL39,SRP14,EEF1B2,RPS7,RPL26,RPL29,RPL10A,SSR1,RPL23A,SPCS2,RPL28,SRP72,RPL35A,EEF2,RPS24,SEC61A1,RPS16,SPCS3,RPS20,RPL6,APEH,RPS27A,RPS13,RPL10L,RPL13A,RPS29,EIF2S1,SEC11A,RPLP1,EIF1AX,RPS28,RPL15,SEC61G,RPS5,RPN1,ETF1 |
| 9.113e-17 | -36.93 | DRG1 (developmentally regulated GTP binding protein 1) | protein interactions | 4733 | 353 | 172 | 19454 | 5460 |
G3BP2,COIL,RNF11,CLDN1,PRRC2A,RPL35,EIF4A2,SEC61B,RPS9,RPL37A,EIF3K,FAM91A1,FAU,BRCA1,ELMO2,RFC5,CUL3,NOP16,RPS24,PPAN,STK16,POLR2C,RPS11,EXOSC3,EZH2,RPN1,ANP32A,RAF1,FEN1,NAA15,NTMT1,EGLN3,RPL7,RPLP1,SOSTDC1,RPLP2,PHB1,RPL8,RPL9,DCAF11,WDR11,BRIX1,FBXW7,RPL4,MTDH,SQSTM1,RPA3,RPL26L1,RPLP0,METTL14,EIF3J,RPS14,ATG16L1,RPL22,RPL13A,PTEN,UBE2I,RPS20,PRKRA,METAP2,CCNF,MAPRE1,CHORDC1,HSPA14,EIF3E,RPS13,SEPTIN7,RPL23A,HAPSTR1,NKRF,SRP72,ILF2,RPL15,CCDC47,RPL35A,ACTA2,RPL12,AIFM1,SSX2IP,CALR,STAU1,SSR3,UFL1,AKAP1,EP300,HSPA8,RPS28,NUFIP2,RPL27A,MTF1,RPL10,ESR2,ANAPC2,LMBR1L,RPS26,FTSJ3,H1-10,LAMTOR1,RPL39,SFN,MYC,RPS4X,RPL28,KRAS,CDK5,PABPC1,RPL31,RPS23,RPL18,SEC61G,RPS7,TRMT1L,LYAR,NOB1,EIF2S1,RPS10,PRCC,DDRGK1,XPO1,RPL6,IFI16,EIF4E,ZC3H15,RPS15,EXOSC4,RPL27,BAP1,HEXIM1,SSR1,RPA2,CFTR,SRPK2,EIF2S2,PSMA6,RPS3,PSPC1,UBE2H,PDCD4,IGF2BP1,SPOP,EIF3G,RPS17,RPL7A,SUB1,RPL17,MEPCE,DHX9,RPL3,MAP1B,SH3GLB1,ZFP1,ACADSB,DNAJC2,RBM34,RPSA,TP53,NAA35,CDC5L,RBM42,RPS27L,IFRD2,RPS16,CAND1,DNAJC1,FZR1,RWDD1,RPL32,RPL10A,RPS2,SNRNP70,RPL24,ELOC |
| 9.157e-17 | -36.93 | ILF3 (interleukin enhancer binding factor 3) | protein interactions | 3609 | 861 | 352 | 19454 | 5460 |
LGR4,VAMP2,EZH2,SF3B5,TRIP4,PLSCR1,RPS24,TRIM37,MRPS35,RPL23,OCIAD2,PHB1,HP1BP3,RPLP1,XPO5,RPL7,CSF2,CACYBP,WDR77,PRDX3,PPP1CB,APOBEC3C,PPARG,CCDC86,CRY1,GPC1,UNC45A,G3BP2,CUL2,CUL3,ZNF668,LMNB1,RIT1,ZNF22,RMDN3,SERINC1,RPL37A,RPL35,DYNLL1,RPL7L1,RPL19,MRPL11,RPL15,EEF1A1,DDX39A,ILF2,PC,RPS13,TIAM1,MPHOSPH10,RCHY1,HACD3,CTDSPL2,TOP1,ZBTB2,SLC25A17,TPT1,RPS14,LSM2,GRM2,LMNA,JUP,RPLP0,MTDH,NUCKS1,RPL4,DGCR8,AATF,KPNA6,USP14,PPP1CC,TUFM,IVNS1ABP,EIF4A3,TRIM24,PTEN,RPS20,PRKRA,RPL13A,RAB14,TXN,RPL22,TENT2,ISG15,SOX2,SEC61G,GLE1,RPL18,RHOBTB1,PABPC1,RBM3,HNRNPDL,RPL28,RIOX2,MDFI,MRPL9,AGR2,HSPB1,EED,CORO1C,EIF2S1,UQCRH,SHMT1,PABPC5,RPL27A,PIH1D1,XRCC5,SNRPA,EP300,HDAC5,HSPA8,STAU1,HNRNPA0,EMC1,RPL39,H1-10,FTSJ3,NSA2,ICAM1,SF3B4,PSMD6,SNRNP40,USP16,ATP5F1B,RAP1A,UBL4A,FGF23,DUSP1,DNAJC2,RBM34,SNIP1,RPL3,IMP4,KARS1,COPS5,CSNK2A1,TMEM107,SNRNP70,RPL10A,RPS2,SYNCRIP,DNAJC1,RPS16,CDC5L,SURF6,TMPO,RBM42,PLP2,MRPL10,ZNF326,RPA2,ZNF770,HEXIM1,SNCG,RNF113A,HNRNPH2,MRPL40,MRPL41,HSPA5,PTPN11,SUB1,MORF4L1,RPS17,RC3H2,SPOP,MARCHF3,ELAVL2,ATP1A1,ZNF330,RPS3,EIF2S2,RALA,SRPK2,NMI,ZNF263,B3GNT2,RAF1,RPL29,ACTN4,CHMP4C,NDUFS6,RPN1,RPS11,HNRNPA2B1,HSPD1,DHX16,SSRP1,HNRNPA1,DROSHA,DICER1,HNRNPD,IFIT2,RPL9,RPL8,RPLP2,NUP35,DHX15,PGRMC1,EMC9,PSMA3,BIRC2,UCHL3,RAB11A,BRCA1,ILK,RPS5,HSP90AA1,RSRC1,RPS9,SEC61B,SNRPD1,ACTB,MRPL23,NDUFA2,FBP1,MAP2K3,TAF1D,LLPH,SFXN1,NKRF,PPP1R12A,RAB1A,FAF1,RPL23A,NOC4L,TRIM63,PSMB11,HUWE1,ELOVL7,SPATS2L,LAMTOR2,IRF9,GRSF1,MOV10,KRR1,PTPN1,RPL12,PRR3,IL18,DCUN1D1,MRPS23,CDK9,MDM2,UQCRC1,METTL14,PICALM,STOM,RARS1,RPL26L1,RPA3,RTN4,SPCS2,MRPL17,BRIX1,MRPL20,METAP2,EIF2AK2,CCNF,NDN,VIRMA,TRMT1L,RPS7,H1-3,RPS23,LSM14A,RPL31,EWSR1,RPS4X,WWP2,RPL6,IFI16,DDRGK1,CTNNB1,YWHAH,MAGOH,DDX1,RBM5,RAB31,HNRNPL,CCT7,MTF1,TOMM22,MRPL12,CNDP2,RPS28,DDX39B,DDX5,SF3B1,PHB2,FXR2,TRA2B,UFL1,HNRNPC,PRMT6,HNRNPAB,MYC,SNRPB,BTF3,FBXW11,PSMD14,CKB,H1-1,RPS26,CMTR1,VEGFA,PRMT5,MATR3,RPL10,TP53,RPSA,STRBP,PIK3CA,NUPR1,PSME1,DHX9,HNRNPK,NEDD8,RPL17,MEPCE,ENY2,DPP4,GAPDH,API5,RPL24,MAP4,LSM3,KPNA1,RPL32,MRPS9,SSBP1,RPS27L,FZR1,CAND1,AGO1,SSR1,LEMD3,PML,IRF3,RPL27,BAP1,DLAT,WDR3,RPS15,RPL7A,RAB2A,CHCHD4,CDKN2AIP,UBE2H,IGF2BP1,PDCD4,PSPC1,SF3B6 |
| 9.823e-17 | -36.86 | colon | COSMIC cancer mutations | colon | 16406 | 4784 | 16828 | 4835 |
MMP20,GTF3C4,DNM2,OR4K13,TSPYL4,PLCXD3,C1QL2,REG1A,CLRN2,SRD5A3,DCAF16,ALG5,DEXI,STARD5,FMO1,ABCC2,SUGP1,ACTR1B,STAP1,SMARCB1,HTR2A,CD59,ECD,PRELID1,APMAP,ETFA,RIMKLB,AQP3,PSMG4,HS3ST3A1,TICAM1,HIGD1C,TLR5,LCN1,RFC4,PNPO,OR2D3,COTL1,GPM6A,CHST10,KCNG3,SOX9,APEX1,PRSS1,PSMC5,ITPRIPL2,GAB1,JMJD8,AKT2,WDR12,IAH1,KLF12,MLN,ZDHHC17,MAP1B,FBXO31,VSTM2L,PIGK,PELI1,CNOT8,NEU1,VSTM4,AMELX,GLO1,RAB1A,PDCD1LG2,TEF,ANKRD10,SCN2B,ADD2,SOD2,PCP2,TCTA,TMEM231,ACTL6A,ACP2,FOSL2,GNPAT,TMEM126A,SETD3,GPR75,SYPL1,CHTOP,ZNF343,STARD7,DIO2,EGR1,ZNF436,WBP11,MAGEA4,STT3A,RBM3,RRP7A,CCDC126,RACGAP1,CORO1C,ARHGAP15,RHOH,HYAL2,UBE2S,ERLIN2,NPBWR1,PIK3CG,RPSA,BCKDK,TRMT5,OR9I1,APOC2,CYB5B,ZCRB1,MED4,NAP1L5,SEMA7A,MRGPRX1,HPCAL1,LIPT2,GABBR1,ERCC3,THG1L,PDLIM4,RPF2,XBP1,TIMM13,TBC1D1,GPR34,CHRM5,NACC2,NAP1L3,CEACAM5,MTA3,DRD3,EMILIN3,CA14,DIS3L,TACR1,ARHGAP19,CEP57L1,OSBPL8,CCDC22,NDFIP1,KDM1A,PSMG2,DTL,SNN,SNRPA1,ABHD2,ARL6IP5,ANKRD46,CEP70,CTDSPL2,GMNN,CYP26A1,NUDT1,RALB,ISG20,TMEM87A,UNC45A,FKBP2,PRSS35,TBCEL,EDC3,SAP30BP,HAPLN2,AANAT,ANKH,YKT6,VPS26B,CAMKV,ESYT1,F2,ARL5B,BIRC5,MFSD3,TRAPPC3,CSRNP3,NRGN,LDB1,WNT2,GMDS,IFRD1,DEFB1,ACSS2,MAP1LC3B,PRSS37,PDLIM3,CTLA4,RBM5,ATF3,RANBP1,TMEM176B,CEBPE,RPL22,DLG3,B3GALT4,RHOU,IMP4,HELT,TRNP1,PDE6A,SERPINB9,MT1X,UBE2V1,TIMMDC1,SNX11,RPLP1,MET,FZD6,RETSAT,POPDC3,SLC7A11,ADIPOR1,PRM1,GAL3ST4,GFM1,EMX2,SEC61G,CENPM,SSH3,HOXB8,MEA1,TAF9,SCHIP1,HMGN4,CMBL,COX7B2,CDKN1B,OR6C4,NMRAL1,MAT2A,RFX5,TRAPPC2L,TMEM198,SCG5,PHOSPHO2,STRADB,LRP3,SIAH1,NCK1,TMEM168,USE1,ST8SIA4,TMEM220,CD200,TRIM62,TEX19,ZNF655,GPR78,HNRNPAB,AHSA1,PLEKHF1,ZBTB6,KCTD16,SLC15A1,BRS3,ZMAT3,TRAF1,RSL24D1,RASSF4,SERPINA3,KCTD20,CLK1,SKAP2,DOK6,SEMA3C,PSMB4,HERC3,DDX39B,CGRRF1,LSM4,HSD17B8,IRF9,CDR2,PTGER2,NETO1,NAA30,C9orf72,ZSWIM7,WTAP,RPL31,PDCD10,GDAP1L1,SSBP2,LRRN4CL,NOC4L,UQCRC1,AKR1E2,CRHR1,OLA1,PRPS1,HAS3,MGST3,TSPAN3,BAD,HNMT,ERRFI1,FA2H,SERTAD1,KCNIP2,ZHX1,GPR83,LPCAT3,ZCCHC7,PHTF2,PPIL3,DPAGT1,CTSA,LRRC14,ZBTB26,PDCD5,PRDX3,EMILIN1,BTBD10,EIF2B2,ZMYM6,ARF1,GNG11,HMGB1,PHF7,MRPS26,CKB,THAP6,TUBA1B,METTL18,RSBN1L,GAD2,SEC61A1,TTR,ASB11,RGS1,SDHC,RHOG,NOL12,FAM83A,CDC42SE1,COX7B,BGLAP,CXCL10,FBLN5,LYRM2,FOXD3,MAEA,EID2,KIAA1958,ZNF345,TPD52L1,ZNF770,UBXN2B,DUSP18,SVIP,SMUG1,SLC37A4,CDH7,ASCC1,PLEKHF2,SNRNP70,SERINC1,GLIPR2,MID1IP1,TDP1,SPCS1,RPL19,IL21,SLITRK5,DDIT4L,SAP30,RNASE4,FGF16,POU5F1,MSN,HBM,ZNF362,SLC6A7,MAGEB1,DICER1,EZH1,ARGLU1,TECR,MRPL16,RNF7,MAP3K3,KRTAP4-1,ARL11,FHIT,UBE2I,UCP2,TMEM106B,MFAP1,MXD1,SLC41A1,LAMTOR2,PNRC1,LSM12,FIG4,CXXC1,RPL7A,DCTN4,SEC22A,MAP2K3,DOK5,ZDHHC24,PPT1,B3GALT2,ARF6,MRPL12,FGR,SPHK2,FAM20C,RCHY1,UBE3A,PDZK1IP1,OR5K1,PDE6D,OR4B1,LRFN3,S100B,TNIK,RIT2,IFNA13,CACNG3,ZC4H2,CETN2,TADA1,ZC3H14,CBFB,EFNA5,ASPM,SH3BP4,LEP,SMARCE1,PITHD1,WBP1L,OAZ3,VCPIP1,TCEA1,HM13,BCAS4,SLC39A10,MCCD1,MB21D2,LCN15,PGAP3,RNF182,SMAD9,RELL1,TIMM17A,UFSP1,PTPN5,LIPA,SNRPD1,CCL24,JUNB,ALCAM,PREP,SHC3,CDC26,STK38L,MVD,PIGC,ARFGAP1,CYP4F22,RPL28,CACNB2,HCFC1R1,FIS1,EDEM2,SLITRK1,DDIT3,SRP72,PLP2,DUS4L,ABCF1,RNF139,NUP62,SMG5,DYNLL1,LYPLAL1,HSDL2,OPRL1,CCND3,ARL6,STX5,RAB11B,LEMD3,CSRP1,IRF4,TBC1D16,SLC7A1,CA12,SPATA4,CMTM7,ADRB3,FMOD,IFNAR1,SDR16C5,SLA2,MARCKSL1,CCL11,RPAP3,RXFP2,RAB9A,HINT1,THOC6,PYCR1,TNPO2,CLP1,CLPX,OR5AN1,ATG3,CFTR,INA,MYLIP,FAM174A,SUPT4H1,VPS39,IFI16,PTPRZ1,SART3,PSMB10,CHMP1B,CDK17,TMEM39A,ART5,ATP6V1D,CDKN2D,GPR37,ESD,VWF,MLH3,PCBP4,FAM193B,APOBEC3B,BLVRA,CRYZ,FOXC2,PITPNA,RAB32,CRYBA4,BARX2,PSMD1,MPP1,ADH1B,SRM,MED27,RANBP10,OR4M1,BMPR1B,SPDYE4,TULP3,HS3ST1,LSM5,DCTN3,PRKCB,IRF2BPL,PABPC5,HCFC2,RWDD1,SLC25A3,RBM41,COPE,CKS1B,DYNLRB2,SPAG11B,HBP1,SEC14L5,RPL4,RGL1,SUV39H1,TTLL10,ATG16L1,HDAC11,SIGLEC5,DIRAS3,TP53TG5,IZUMO2,ZNF200,TPST1,HNRNPH3,AGGF1,LCP1,PCYT1B,CSF2,PRELP,KRT8,GJB1,GCHFR,CHCHD2,SKP1,CNN3,CPT1B,RBM27,ZBTB39,ANKMY2,MAD2L1BP,TMEM47,LY96,AP1S2,APEX2,ADORA3,SF3B1,TAB1,AKR1B1,TMEM185A,NDUFS2,PAIP2,SNRNP40,FAM83B,PIK3CA,IVNS1ABP,CDH11,PSMC3,JAKMIP2,GSTM4,CRTC2,NPM3,TMEM38B,TSPAN15,NUDT2,PSD2,PEBP4,GH1,BAX,ATP1A3,FEM1C,COCH,COX6C,PICALM,LST1,XAF1,PIK3AP1,RPIA,VTA1,CAND1,PRNP,HSD17B10,GABRA1,TMEM89,MIS12,CBX3,DR1,HS2ST1,GTPBP8,LYPD6,ELMO2,TRPC1,ASPA,BCL9,SSX2IP,SYNPR,BCL6,GSTCD,E4F1,TMED9,GTF2F1,DLST,CA2,SNX10,SGTA,USP6NL,MTDH,ZNF263,TPPP3,IGSF11,CYP2C9,MRPS34,ATAD1,TRIM45,DUSP21,RBBP8,MGAT4A,SGMS1,OLR1,SLC19A3,FBXO8,NDST3,MPPED2,PRL,CDC7,IL2,SEC13,TNFAIP8L1,NBN,VMAC,AIPL1,PEX13,TBC1D25,TYROBP,WDR11,NHEJ1,FHOD3,SLC35B3,XRCC5,ACCS,TIMP4,SNRPG,ADTRP,WDR5B,ZDHHC4,CDC20,COX6B2,TMEM170A,RNF133,ZNF451,PRKCE,WDSUB1,GNRH1,TSPAN17,PRKRA,DBR1,TAS2R13,UBE2E2,TRAPPC13,HGS,RHOBTB3,POLDIP3,POLR2L,FSTL1,MT1E,CRISP1,DPH3,LRRC40,ELK3,CD81,SNRPB2,LZTFL1,TFB1M,SUMO2,CCR4,CHRAC1,KLF3,TNF,GGH,NUDT9,CYGB,PPAT,IL17F,SESTD1,CARTPT,KLHL1,FOXA3,PARP2,NF2,ABHD12,BANF1,PHF13,RPL26L1,CGGBP1,NDUFA1,GPR35,DDAH1,HFE,ALG11,MCL1,FAM53C,GSTA2,TMEM127,HCAR1,RB1,TRIM29,OIP5,CORO6,DPH5,PNMA3,ZBED1,CTXN3,DCAF12L2,PLSCR1,PTP4A3,HSPB2,COMMD9,STK3,CBLN1,TNKS2,LILRA2,LY6H,NT5DC1,MRPS18C,TRIM36,JAK2,PROK1,PAQR3,CREBZF,CYP3A43,SPEM1,PDE4B,CCIN,UBE2L3,TTPAL,PMAIP1,EIF3G,MEPCE,HUWE1,ABHD10,CPLX2,PRND,SREK1IP1,CNTROB,FTSJ1,AKR1C1,CSNK1G3,RAB39B,MRPS11,ICOS,NINJ1,BLCAP,ITGB5,RGL2,NDUFC2,TMEM205,TRIM34,YIPF3,TCEAL8,LXN,RPS2,CAV1,B4GALT4,OR4K2,GRM1,PCGF6,TAF1D,SHPRH,KCNJ10,SLCO3A1,ADORA1,SPATA2,HOMER3,MAGEB10,CXCR3,SLC25A1,STAMBP,HNRNPF,CEND1,ZNF511,EHD4,FAM81A,TNR,OR6X1,TM4SF18,BOK,OR8H3,SLC8A1,LSM14A,CAPN2,OST4,YWHAZ,STARD3NL,ICAM2,ABHD8,RNF222,REEP4,AASDHPPT,CCNA2,TM4SF20,GJA1,MAGED2,SLC29A1,SURF2,SPP1,FAM149B1,FRZB,CHRM3,TSR2,ARL2BP,ING2,ZNHIT6,GPR17,GPC1,PLCB1,PRSS23,LIAS,CITED1,ARL4D,TXNDC17,NPY1R,PSMD10,GCLC,CPLX3,TNNI3K,CTU1,EPHA4,GXYLT2,KCNJ2,PSMB7,TNFAIP6,FBXW7,PLG,DMTF1,CDK12,DLK2,RNASE9,GADD45G,YPEL4,LDB2,PRSS8,TMEM107,RPA2,RGP1,CCDC90B,PIWIL1,TRAF3IP3,TAB2,SRPK2,CPXM1,THAP1,UNC79,FBXL4,CD34,PRCP,EID2B,DCTPP1,TMEM100,OR4A47,PLAC1,SCAND1,PSMD7,SIN3A,CDK7,RAB6A,FKBPL,RGN,CTTNBP2,PDE2A,ZNF428,CDIPT,TNFSF8,PYCR2,MED22,ARFGEF1,NOG,PMPCA,TLR8,CD40,AIP,TNFSF15,SLC6A2,CRY1,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,OR4D5,TEX261,RNF10,FAM133B,POLE3,KRTAP8-1,GP9,OR51E2,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,POLR1D,GPR160,DTWD2,PSMD3,TRIP4,RPL10,STAR,SUPT5H,PDCL,SLC25A24,GLCE,GK5,SSNA1,IP6K1,PTGFR,IL2RB,FBXW4,P2RY4,TAS2R7,ST3GAL2,CD209,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,GNA11,SERTAD2,HSPA5,HSPB6,THAP8,WDR45,MPV17L2,CRYBA1,NRM,TMEM229B,GNB3,HINFP,CMC1,NUFIP2,VAV2,CCDC3,ITGB8,BTG2,NR1I3,LRP10,PAIP2B,TRIM44,THOC3,BOLL,MX1,GLOD4,PIGA,VPS54,SLC25A27,TGFB2,RBMS2,ZNF622,ATG9A,S100A11,RUSC2,CD9,OR1M1,GADD45A,IGFBP3,GRPR,DPEP3,TMEM183A,BTG3,NPC2,TMEM115,NUPR1,PNPLA4,PIAS1,LRRC28,TCEA2,PARD6A,RNASEH2C,HSPD1,EIF1AX,SPG21,TIA1,SLC22A6,DDR1,TMEM81,SAP18,EXOC3,CAP2,LRRC8A,GNGT2,SSPN,CNPY1,OR5M9,HAUS2,ELFN2,RP9,GALC,LBX1,NKAP,RDH11,KCTD3,PIH1D1,BRAP,TANK,SYNGR3,MPG,DMPK,ELFN1,CDC23,MBD3,CCR7,IGF1,RXRG,SNAP25,THUMPD1,GORASP2,TTC9C,PELO,GMPS,IL18BP,RASL12,ANXA4,GALNT2,RRAGB,SNRPE,DLGAP4,CMA1,GRIK1,TRIM26,IER3,NUCKS1,CENPL,KLRC2,TOX4,IFT172,CYTH4,TMBIM1,CPNE2,RAMP3,FXN,SUPT3H,UPRT,MECR,SGIP1,MRPS17,FEM1B,UBE2G2,MRPL9,FAM151B,ZNF518B,ADCK1,CYBRD1,MACROD1,FAM136A,SLC35E4,SLC25A5,PRR13,WSB1,LYZ,TOPORS,OAZ1,PTP4A2,FAM3C,MFAP3L,SLU7,VEZT,IRF7,KLHL25,TMEM165,OR8B4,RPE,SULT1B1,TADA3,TRAM1,ECHDC1,FUNDC1,AP1M1,UBA52,TMEM196,IMPA2,MDC1,TRAPPC6A,SP1,CCSER2,ITM2B,MTCH2,MGMT,GIN1,TKTL1,RPL18,TBCCD1,TRAF6,ROCK2,KCND3,FUBP3,VPS72,KRIT1,RPS10,SPRY1,CCDC106,ETNK2,CLDND1,SCML1,TAPT1,MED10,TYMS,ZFAND6,NAA16,SLC12A2,RPS20,RUNX1,GJC1,ATP8A1,CIAO1,KIF3C,GHRL,VPS18,ZNF581,SUCLG2,PDE7A,DUSP3,SSBP4,RASSF8,KCTD17,CLEC6A,RBP2,AQP11,LCORL,EDA2R,LMO2,FKBP1B,PSEN1,MAGEC2,OR13A1,YTHDF2,FAM161A,ANKRD6,PDE12,PFKFB2,ARHGAP12,EIF5B,SRFBP1,DIRAS2,ACER3,MREG,CNR1,CAMLG,PLA2G12A,NPY,SLAIN2,ZBTB2,MFN1,DAD1,TAS1R2,UBFD1,GSTM2,NAA35,PPP4C,PPIG,NRBF2,EFHD2,GRXCR1,GGT7,DNAJB2,PSMA2,NICN1,TMEM208,RAB30,RSAD2,GABRA2,SST,COMMD5,PFDN4,UGDH,AP2S1,PGAM1,RNF121,CCSAP,RPS13,EPO,CHCHD3,NFKBIB,MMP21,ZNF280B,EID1,HDDC2,CD1A,LPAR1,HSP90AA1,DCUN1D5,PPIH,FNDC9,FOLR2,PDRG1,PTPN22,SOCS3,LNX2,SNX18,TYW3,RFC2,GNB4,CPNE1,ZER1,CNTN1,ACTB,DDAH2,MATN4,AGAP1,UBE2M,PIR,TRIM10,SLC6A12,UBE2E3,OR5AP2,ELAVL2,MOSPD1,FCHSD2,ISCU,TNNC2,GTF2E1,OR8I2,SMC4,RAB22A,AK5,CLVS1,FAU,KBTBD4,PNO1,CYP2F1,PSME1,SMARCA5,CNPY4,IL1RAP,DRAM1,VKORC1L1,BAK1,ATP1B1,ELK4,FAIM,GPR85,PPP2R3A,FZR1,RILPL2,DRD1,SLC22A8,SMAD4,SLC1A3,LRRC1,NUP37,TM9SF4,TCEANC2,GPBAR1,ITGAV,MXI1,USP5,FERD3L,FOXP4,TMEM182,RNF126,LDHB,RPF1,FXR2,AURKAIP1,AKR7A2,ARMC1,GABRB2,HSCB,SYVN1,CES5A,TFEB,GRID1,CCDC122,PPP1R12A,IL6,RERE,TLR2,FGF10,HECTD1,DYNC1I1,LGR4,PSMC1,TTC32,PAIP1,SSRP1,TWSG1,OCIAD2,MED21,RLN2,OR9K2,NDUFS3,HPGDS,DNTT,OSBP,GOLGA5,MORN4,GIMAP4,RPAIN,XXYLT1,TBC1D4,UNC119B,MRPS7,CCL20,ZNF575,ARHGAP5,VTI1B,SPATA6,FAM162B,GLT8D2,EIF4E3,MYOZ3,TCAP,ARHGAP25,DES,RIC3,LIN7B,PCDH9,ZRANB2,TNFSF13,FLRT3,STIM1,GRPEL2,FTL,LRIF1,TMC7,SERPINI1,IDO1,PPM1D,KLHL12,CXCL12,FLCN,MSL2,SLC25A28,SLC39A3,RSRC1,RPL35A,ZNF668,CD248,HMG20A,BTF3L4,TLE1,ARL6IP6,PNOC,CYP27B1,IL15,MRPL10,YBEY,NTPCR,TMEM14B,GNG5,NIF3L1,UTS2,RRN3,DHPS,SCPEP1,OGN,TMEM190,NSFL1C,POLR2F,PADI2,NDUFB10,POMT2,LRRC57,PLSCR4,MOG,NMI,SCN3B,OSGEP,NDUFA2,RIMS4,NUP50,IFNGR1,TPGS2,PTGER4,TOMM20,TRAF3IP2,BAHD1,DHRS7B,IZUMO1,PEG10,PSMB6,ZCCHC17,PIP5K1A,CHRDL1,RASL10A,METTL6,IFNA2,IDH1,TUFM,OR51M1,GNG13,VPS28,MPZ,KRTAP12-4,CD2AP,SRC,PIK3R3,LANCL1,CISD1,MORC4,SLC35B4,MKKS,TERT,YTHDF1,TUBA1A,RPL7,FCGR2A,NAA50,CELF6,SH3BP5L,MED31,LUM,SEMA6C,CCDC85B,MTMR6,NEUROG2,UNC50,ICAM3,HMX2,CHST11,CKLF,CCT7,PSMD12,KCTD15,SLC25A11,PAFAH1B1,HNRNPD,PDCD1,MS4A7,RAB33B,SECISBP2L,IFIT2,CDC42EP3,RNF115,MCM3,RCE1,MGAT1,RASGRP3,ENTPD3,RGS19,SESN3,CDSN,ZNF692,SLC25A44,PSMD14,TESC,YWHAB,THY1,EDNRA,TBC1D24,ST6GALNAC3,LEPROTL1,TMEM95,SPOPL,SYT2,PHB2,TTC1,MMADHC,BMP1,NR1H2,PRPF31,STXBP6,TPBG,KCNQ5,DAPK1,PDE1A,LILRA1,NFYB,SLC25A17,EEF1G,LRWD1,ZCCHC12,ARRDC3,ACTL9,GTF2A2,GPR15,PPARA,COPS7A,RNF20,MICB,TOR1AIP2,NUP153,STOML2,OTUD6A,RERG,POLR3F,RPL35,FRS3,RRAS2,TPT1,SNCB,ATL1,TXNL4A,USP14,NANP,TSC22D3,GNA14,CXCR6,CISH,ZMYM4,EIF2S2,BTG1,AGPAT1,ASB3,CHMP5,HDAC6,PBLD,RNF39,ANAPC13,CNTNAP1,TMEM176A,DUSP26,EYA3,TLR6,RPN1,CD151,KCTD9,DLG1,P2RY11,IL3,MSX1,CHRM1,HEXIM1,PRDX2,DPP4,LMBRD2,MRPS33,LMO3,UGP2,EIF2S1,PAX6,STAT1,ZNF507,PTN,TMEM31,KCNA3,F10,SSBP1,NEK2,NDUFV2,ZNF526,NDUFB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C1,NEUROD2,BABAM1,METTL15,CINP,FBXW11,PPFIA2,CNDP2,THBD,OR4D6,BCL7C,IL1A,FRRS1,SNRNP48,ATG4C,GFPT1,SDHB,CENPW,RWDD3,TXNDC12,ABHD5,CXCL13,CKS2,RORB,EPHX1,CCDC160,RPA3,MOXD1,NEGR1,SIT1,FDFT1,ADAM21,CLDN3,THAP7,UAP1,MGAT5B,PTAR1,CRLF3,UCN,PTEN,RLIM,DEPDC1B,INO80E,NTRK2,PABPC1,GNG12,APOBEC3G,CNRIP1,USP15,ELMOD2,OR10A4,FKRP,LPAR2,SIAE,GAMT,TOMM6,ISX,GLRX5,RTN4,GNAZ,DNAJB9,ARG2,RNF144B,GNG10,MUL1,SMG9,CTXN1,NRN1,MAPRE1,METAP2,MME,ZFAND2A,SEC22C,CCR1,REN,DTWD1,ASTN1,ATXN10,NCBP2,TBC1D13,SOD1,SMPD2,TP53INP1,IQCK,AVL9,DECR2,FAF1,VEGFA,CRAT,TM4SF19,PTPN11,SOBP,NOTCH2,NAPA,GNPDA2,TMOD2,TMED5,HARBI1,PFDN2,LTB,TCEAL1,USP16,CLCN6,AK3,SLC25A12,HMGCS1,DDRGK1,PSMA1,RPL32,SHOC2,HDHD3,DRGX,OR10A6,OR4D2,KLF4,COPS7B,DENND2D,RNF34,ACBD6,PRDX1,FAM53B,TAF10,ATG7,NPW,TUSC1,NFKBIA,PREB,LRRC8B,ETF1,TRIM68,LRRC61,UBIAD1,GTDC1,TSNAX,POLR2B,UBE2W,PARL,DHRS13,RFC3,SLC7A8,GPM6B,REG1B,FBXO22,EGFL7,TMEM59L,ACP5,HLF,SERPINC1,ATP6V1A,RBM38,NKIRAS2,FAM181B,ACVR1C,IL1R2,TMEM41A,KLF9,PIP4K2C,STUB1,TRAK2,SERPINB1,SRSF2,GSTA1,UBLCP1,AVPR1B,ST7,SNRK,TEX264,ZNF821,GTF2H5,RPRD1A,SLC25A10,VRTN,CTXN2,HINT3,DDX50,PPP2R2C,BST2,STK4,SPON1,TNKS,SLC22A17,PLS3,CYP1A1,ST8SIA5,PTH2,MTF1,RNF148,PRICKLE2,RPL27,PPP1R1A,MSTN,CLDN9,SYNCRIP,TRMT112,SLC35F2,VGLL2,SLC16A10,DIO1,IFNB1,CSH1,UBL5,BTN2A2,UBASH3B,POLA2,POLB,MNS1,KIAA0513,SEMG2,CCNH,SPSB3,KANSL3,TOR1B,UGT1A1,FAM83C,MRPS9,LTA,ABCG2,SEMA4C,FBXO7,RABGGTB,SLC2A3,CLLU1,RPL23,ANP32A,SPIN3,HP,VAMP7,CTTN,STOM,CDNF,TNFRSF1B,TGFBR2,CEBPG,CAPN1,USP3,METTL22,CYP2C8,ASZ1,TTL,TMEM70,MPDU1,VAMP8,PRMT6,PMM2,PPP3R2,PRSS12,TIMP3,ZNRF1,CHST13,CLEC18A,SMAD1,SPC24,AQP2,FKBP8,GABPA,KLHL24,PPP2CB,SF3B5,RCL1,PPAN,IL2RA,STAT5A,COPS5,FPGT,LRRC3B,EIF4A2,MAGEH1,OTX2,PRDM4,FEZ1,PLCB2,MAP2K1,APOBEC3F,TMEM167B,HSD17B6,RNF8,PEA15,AKAP8L,EP300,ADAMTS10,MRPL20,AR,IFI6,LLPH,GSTP1,CCL2,OR8B12,PPM1K,RNASE1,TMEM45A,CGB8,NLRP9,FAM43A,LAMP2,TMEM237,PTPN4,OR10P1,RIT1,CHRNB2,GPX7,ELOVL1,MORC2,SSR2,SOSTDC1,EFNA3,TPM3,SNRPB,GLRX2,LANCL2,APOBEC3H,ASB7,PRKACB,VDAC1,FEN1,CLPB,KLF1,ODAM,JKAMP,CBR3,SEPHS2,CLEC2B,ADD1,FCGR1A,SCML2,DNAJC19,VGLL4,ELF5,CLDN12,GPR176,PKP4,CHKB,CCNY,CRHBP,CNOT2,OTOS,PLEKHO1,MYBL2,ZNF326,GSTM5,ERAS,RAB19,UMPS,CD1C,MRPL22,SS18,CDCA7L,SIAH2,CHCHD6,POLR1B,CER1,EPS8,RFXAP,UPK1A,HOXC4,BIRC2,MTM1,IFIH1,NUDT7,FCGR2B,ORC6,FLOT1,DROSHA,NR2E1,STARD4,THOC2,DCTD,FAM177A1,MCM4,SCNM1,PDAP1,SOX14,CEP19,CHMP4C,IGF1R,CX3CR1,SLCO2B1,MAVS,UBP1,KLHL22,TSN,STOML3,STAU1,KLK6,FKTN,DNAJC3,RNASEH1,TMED7,SERINC3,SLC41A3,STMN2,RGS2,DUSP19,NME1,PDHA1,ADPRH,BCL10,NOS1AP,KCNMA1,MBD5,ABHD4,PCDHB1,BRCA1,TRAF2,RBM7,KCNK13,CDK4,NPR2,DPY30,CNNM4,NR1I2,TAS2R40,LRP6,PYROXD2,MRPS21,LCA5,STK24,NDUFB4,RAC2,IFRD2,CEP97,ZNF501,POR,ST3GAL5,SLC32A1,FAM163B,PARP11,CSNK1A1L,SOX2,ST3GAL1,IL18,DERL1,PRKAB1,UQCRH,DPEP1,MTHFD2L,IRF3,CD36,STXBP1,KLC2,PAX9,PCMTD2,STOX2,ERV3-1,COMMD8,ITGA6,CSNK1A1,PELP1,IFNA10,MT1M,DEFB114,TFE3,SH3GLB1,THTPA,PREPL,RNF113A,EFNB1,GOLGA7B,TSPO2,OLFML3,RPLP0,IL10,UBE2V2,FUT9,PHYH,HOXD12,RTKN,NTN4,FABP7,ZBTB17,BCAP29,CREB3L4,B3GALNT1,EIF3K,CD274,KHDC1,NAT2,SPECC1L,BZW2,OR10G9,TSPAN5,RINT1,EIF4E,TRIM5,TMSB4X,COX4I2,CDKN2C,LHFPL4,CALHM3,BLOC1S2,SNCG,SNAPC3,DDX39A,RAB40AL,AKAP12,IGBP1,SSU72,GPX3,PROS1,TMEM204,EWSR1,B9D2,TGFB3,ACSL4,TRIM24,MRFAP1L1,DTYMK,CIB2,YAF2,ELP3,MTRF1,ZNF592,EED,MRPS16,ABHD14B,CCDC25,FAM219B,TES,BECN1,LMNB1,GMPPB,CALHM2,ADO,VMP1,CBR4,SLC19A2,MSMP,HSPA8,EMP3,OSTM1,CHMP2A,BCL7B,TOM1,GPR65,TEX30,SEC61B,GBE1,CHGA,TCF23,PAPSS2,TMX3,HTR5A,DNAJC22,EIF2B3,SRRM5,TMEM144,TOP1,NRSN2,GPR137,APOO,SNX17,BCS1L,MYO6,ZNF740,NDUFS8,CYP2C18,NKX3-1,F9,PGPEP1,GCNT3,OPRK1,IPO8,TMSB10,CIDEB,ATAT1,ARMC7,TMEM123,DSTYK,ZBTB5,CCR2,ZC3H7A,AIF1L,FCN2,RER1,SFRP4,RGS7BP,CDKN2AIP,CSRNP1,SYP,ATG4A,ZNF862,MRPS23,FUNDC2,HSP90AB1,POLE4,GPHN,ISG20L2,IK,UHMK1,LCP2,CRTAP,ERH,ALKBH5,ADIPOQ,ANKRA2,FAM162A,CTDSP1,CCNB1,NDUFAF4,AKAP14,CRYBB2,TFCP2,CLDN1,ABHD6,METTL2A,CSGALNACT1,R3HCC1,SAT1,RMI2,COL1A2,SLC35D1,SMU1,MBL2,GTF2H2,MAP3K11,JPH4,AMIGO1,PTS,TOR2A,METTL14,VAMP5,EDEM1,GNG2,ACAT1,ZNF287,KDM4B,TMEM184B,LAMB2,SLC13A5,CLDN4,RAB3D,CXCL3,GTF2B,SDF2L1,RUVBL1,GIT2,OAS1,NKIRAS1,HTR1F,OR4Q3,RDH10,LDOC1,GPAM,PDCD4,CREBBP,PRPF19,GREM2,TGIF2,GPX6,POPDC2,CDC42SE2,ACBD7,FAM98A,RPLP2,TRIM54,TMEM106C,NUS1,SRP14,MANSC1,GJB2,WDR3,KRT7,PLEKHA8,ZNF609,SELENOS,TMCC2,KCNK10,SLCO1A2,TMEM164,ACP6,SYNJ2BP,APLN,TAS2R5,TMEM203,FOXS1,PTRH2,CRYBB3,OR4F6,ACTR2,KLHL15,RFXANK,PAPOLB,PLAGL1,SESN2,TRAM1L1,TRAM2,PPP1CB,EHD1,MPV17,CHST1,FCHO2,ZNF576,ISCA2,UPF3B,RABL3,GCA,GMPPA,CYB561D2,PXMP2,ATP1A2,PPP1R16A,MT2A,DDX42,SLC7A14,BNIP3L,CXCL14,ADAMTS1,CLDN8,RPL6,SPRR1B,TUSC3,GLIPR1,SQSTM1,RBM12,RPP25,RAN,TMEM177,FMO2,CREB1,SERPINA5,BICD2,KIAA0408,NAPG,RNF122,KCNH1,DLG4,GTF2F2,OR2H2,PAFAH1B2,CCL17,KIAA1191,NPY5R,CDH13,CXCR4,HSPA14,BRD9,LCN9,HAND2,PGR,POLR3B,PPID,YPEL5,SLC35E1,CAPZA2,RB1CC1,RFTN2,TPPP,CCL8,NAA60,PLA2G15,STX6,OR2A25,FANCG,MAPK1IP1L,HNRNPA2B1,TAPBP,ATP6V1C1,GGCT,RCBTB1,LHFPL2,SCD5,MAFG,ACAP2,NFKB1,PRKAG1,PAFAH1B3,HNRNPK,OAT,MRPS28,RIOK2,OS9,RPL26,POMP,FOS,DYRK2,EGLN3,CLDN22,CRYGD,RAB33A,FAM107A,RNF167,PPDPF,TNFSF18,DNAJC8,UTP23,GNPNAT1,GIMAP2,TOMM40L,EIF3J,FERMT2,RNASEL,CHI3L1,SPTBN1,TNRC6C,IFNG,JUN,TMEM50B,CD47,HIRA,S100A8,RHOJ,CBLN4,WWP1,RAB23,CMAS,SFT2D2,PTGER1,SUMO3,OPHN1,ZNF687,OGG1,CCR3,AP1AR,SMN1,WEE2,PCDH19,RAB5C,PNP,STK38,TIMM10,CAV2,C1QL1,FBXO25,PSRC1,IFI35,CSTF2T,SLC6A11,RAB37,FOLR1,IL6ST,TMEM59,LYNX1,RPL23A,PLEKHJ1,MLF2,ELMOD1,DERL2,TXNL1,TIMP1,SMAD3,SLC25A4,MRTO4,PTHLH,PPP2R1A,EIF4B,STAT6,SNX24,ACADSB,ISG15,OR10G7,DYRK1B,WIF1,FN3KRP,PHYHIP,RAB9B,AMT,KCNIP3,INPP4A,FGFBP2,ARCN1,EZH2,B4GALT3,ZFP1,PDYN,CRBN,VPS33A,SACM1L,CD226,GPIHBP1,WDR44,RAB2A,CTNNA1,CCNF,VAMP2,TRAPPC6B,SNRPA,CMPK1,BEND5,CDH8,CPSF2,OR14J1,GPX5,PCGF3,GDE1,TCEAL7,TMEM14A,UQCR11,NGB,GLT8D1,MOV10,TAF5L,MYEF2,PNPLA8,TOP3B,TEX12,B3GNT2,HIGD2A,TMEM91,SLC43A2,ZCCHC9,CAB39,LIX1,KLK5,DDX4,MRGPRX2,FLYWCH2,GRIA2,LRRC24,SELENOV,LDHAL6B,CCDC65,TDRD7,CD2BP2,HMBS,RBMX2,NDE1,AMY2B,ABHD13,ZBTB45,HRH3,RAB1B,OR5L1,INHA,RPAP2,RGS5,ACTL6B,FAM168A,SNIP1,SLC4A8,LY6G5C,UBE2D1,PGM2L1,ROGDI,SLC23A2,GYS1,AKIP1,SOS2,PIWIL2,OTUD7B,PPFIA3,MED11,CLIC2,SDHAF2,ORAI3,STX18,ELSPBP1,SLITRK2,CDKN1A,GK2,RBFOX2,FOXN2,GLE1,CREBL2,TXNIP,AQP4,GNMT,CCL25,PSMD6,IL23A,SLC39A9,DHX9,FURIN,OR51S1,ZSCAN1,WDR37,EIF4EBP3,CXXC5,OSR2,CIRBP,ANKIB1,ENDOD1,SH3GLB2,EIF2B5,GALE,FUT8,GTF2A1,WBP2,NEK7,UTS2R,MOB3C,LASP1,PHKG1,SPOCK1,SURF4,INTS10,XPO5,RNF103,CREB3,TF,GJA10,SLC25A32,EFHC1,KIAA0040,THRAP3,EEF2,XPO1,EXOC2,ZMYND11,ZNF513,SLC7A4,RNF187,GPR162,APOBEC3C,GSK3A,PRCC,UBXN10,PFDN6,LDHA,NUBP2,SLC20A2,PCDHA5,FATE1,ATP2C1,DNAL4,RC3H2,NUDT19,RANGRF,ABCC5,THOC1,KCND2,NDUFA5,CCL21,PTCRA,TRMT6,HBB,FGF17,CXCR1,NEDD8,RABAC1,WWP2,ACAA2,RAP1A,UCKL1,CD2,POLR2I,TIGD7,FBXO30,RASGRP2,LPXN,ST13,DFFA,IL34,TBCE,SPATA2L,NQO1,IPP,IGFBP4,NPVF,LMBR1L,AKR1C2,TAC1,OPA3,KIF1C,GAS8,CHRNA7,CDKL2,BRMS1,PAOX,CD3G,TMED1,RBM23,BRI3,OCEL1,ADAT1,HEXA,OXNAD1,SERPINH1,RPL37A,ZKSCAN1,CLDN14,HSPE1,PGBD2,SIPA1L1,STAMBPL1,GXYLT1,NUDT16,OR6M1,LHFPL1,B4GALT6,HSPB1,KCNA2,LEAP2,HADHA,SOX21,RAB4A,TRA2B,DHX16,WNT7A,LEPR,STX17,ISYNA1,APH1A,NDUFB8,EIF1AD,NAA11,FRA10AC1,PDIA3,XPOT,CXCL1,SNAI3,PELI3,CDC37L1,NLE1,KRR1,MSX2,RPRML,SNRPD2,FAM13B,ADCY3,DCAF5,ESR2,CDK6,CWF19L1,CTNNB1,RAB8B,SOCS2,INTS12,CYP2D6,SFTPD,CLEC12B,OAZ2,VPS4A,NAB1,ENPEP,RTP4,ZMAT5,LSM6,SYNGR1,PROX1,PRKX,FGF13,ZNF174,USP38,USP39,CERK,SLPI,TSSC4,MAK16,ALDH1L1,NONO,POLL,SPRED1,H19,SIVA1,GFOD1,NDUFAF2,GPR37L1,SNTA1,SNAPC1,HPCA,SV2B,ZNF805,SOST,TCP11L1,EIF4EBP2,OR2A2,MMACHC,TRAF7,MTMR12,DUOXA2,ABHD16B,RAP2B,ZBTB42,TNFAIP3,TAPBPL,ETV6,RRAGA,SIRT7,IQSEC1,NOL4,FYTTD1,BPGM,CDKN3,PPIB,CD164,SPEF1,NUP107,OR52M1,SCAMP2,NLGN2,DEK,SLC5A6,CYP4F8,PRKD3,CTSD,COA4,PGAP2,MRGPRX4,FABP5,NFE2L1,AKR1A1,NOP58,SPATS2L,MRPS25,RBCK1,KIF2A,MIA2,BACH1,INPPL1,ING5,DEGS1,CRYBA2,POU1F1,CYC1,CCDC42,FCAR,NPTN,ARMC8,SLC35A2,ENTPD4,PTDSS1,ID1,WFDC13,ACOT13,TMED3,OR2W1,RPGRIP1L,CCND1,FBXO9,COX7A1,LCN6,OTUD6B,SETD4,FAF2,BMPR1A,ARHGAP21,SCG2,SPINK13,RHCG,MRPL47,TMEM33,S100PBP,MPHOSPH10,AP3S2,KLF10,S100A10,FAM200A,NFYA,DUSP1,TGFB1I1,TOLLIP,BATF,STX8,RAB3C,MTAP,PWP2,CETN3,URM1,CTSK,CACYBP,AP1G2,NDNF,DCAF8L2,ANP32B,CPT2,CHST9,CD99L2,PRIM2,SNRNP27,PDIA6,SDR42E1,UBR7,TRIM32,RNF141,KLHDC8B,PLA2G5,KLK9,DOK4,ARHGAP1,GDI2,MRPL23,GFM2,E2F6,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,POLR3H,TRIM3,C1QC,TMUB1,EDF1,ATP6V0B,TMEM219,ZNF207,MEAF6,UGCG,RPS14,LIG3,LYPLA1,ZNF671,SLC25A31,SLC17A5,PPIL4,RAB11A,CCNI,ASMT,CDO1,CRABP2,DPP10,RPS23,PRRC2A,SF3B4,IL20RB,DKK3,FNDC8,COMTD1,DLX1,AKT1,APEH,FGD2,L1CAM,SNX20,WDR38,FIBIN,TLR9,EHBP1,MDM2,MGP,MRPL13,TMEM156,GSTO1,SPRN,PSMA3,CCDC69,GALNT1,SOCS5,AK2,CNP,RND3,B9D1,NUDT3,LYAR,EXOC8,PFDN5,UST,TOM1L2,ZNF304,MRPL24,MRPL50,SLC30A5,KLK3,SNAPIN,RAG1,ENY2,HSBP1,DHRS4,SLC35A1,IMMP2L,MEF2A,RMND1,MIOS,FAM78A,PPP1R2,IL15RA,OSM,SLC38A9,TLR3,GPAA1,JAKMIP1,ADGB,SENP5,CYP11B1,PYDC2,GRM2,CTNNBL1,GALNT4,IDH3B,CHDH,GNRH2,LRRC69,SWAP70,CYP39A1,HSD11B1,MYL12A,ITK,EIF4H,NCR3,FAM8A1,ATPAF2,KIAA0232,CLU,LMO4,CNIH4,GLUL,CDK5R1,NRP1,NCKAP1,APOBEC3A,ZNF397,ID4,ZNF319,SEC14L1,XAGE5,TAAR1,SLAMF9,ZMYND19,CCR6,IRF1,OR8B8,STRBP,P2RY1,ING1,NHP2,TRIM23,NAIF1,ARMCX1,UBE2A,CHRM4,CCT2,ATP6V0E1,UBE2D3,GABARAP,FGFR1OP2,TCP11L2,GRPEL1,ELMO1,PRPSAP1,LTBR,CASK,GAL3ST1,OR4D11,MMP9,BTF3,CYP27A1,S100A6,DYNC1I2,LHX2,ZYX,UBAP1,CDC73,DNAJC5,TMIGD1,PACSIN3,SLC7A9,ALKBH4,HEBP1,SNAP91,MYH2,VRK1,ROPN1B,PGK1,ATF4,CTNNBIP1,GNG7,GSTO2,KBTBD2,GRSF1,RARRES2,KPNA1,PIWIL4,CSNK2A1,KIT,RS1,OR4D9,AFTPH,LSM3,SUPT7L,JOSD1,P4HA2,GTF2E2,MLF1,NKX3-2,CCL19,MAGOH,TBC1D10C,JAK1,LBH,INO80C,HBE1,AZGP1,ABCB1,FGF1,AZIN1,PSME2,SMAP2,RAB3B,CDCA3,KTI12,NDST1,DNAL1,DHRS3,TNFAIP8L2,DEFB116,MFSD6L,LYG2,AAMP,MX2,TMEM213,GPBP1L1,SYN3,ZCCHC10,MTPN,WDR77,FZD4,MEST,ATP6V1G1,TSEN54,SERPINB10,TMEM215,FBXO42,ZNF24,HEY2,PCDHB8,RBM17,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,RNASET2,SPTAN1,SLC35E3,NPY2R,LRP12,PAEP,RABL2B,NIPA2,CLDN11,FAM199X,TRAPPC1,RMND5B,PGS1,RBBP7,SLC25A21,ZBTB38,TRIM37,HECW1,NFIL3,HNRNPC,SETD5,PTPN1,SPR,PPARG,ARFIP1,GALNT12,ACTA2,SIX5,TRIM21,ARMCX2,AGK,FBXO32,ANAPC2,SMCP,MCOLN1,PSMB5,CCT5,ENPP4,SLC39A7,SORD,SBK2,CD58,AGER,IMPACT,RAB18,IDH2,FKBP14,ARMCX5,ZNF593,PRPF4,TTC4,SCFD1,CCDC47,CACNB4,RPL15,TUBG1,GHITM,TACR3,CIB3,PRMT2,CAMK2G,BUD31,SRP54,TMX4,CCDC127,RCVRN,FAM89B,PEX3,CRYGB,KCNJ11,PPP3CA,CD200R1,FGFR1,HCRT,CAMK2N1,SHC1,OR4K1,PYGM |
| 1.000e-16 | -36.84 | ACO2 (aconitase 2) | protein interactions | 50 | 215 | 118 | 19454 | 5460 |
SPR,SPTBN1,ATG16L1,RPS14,NDUFAB1,CDC42,IDH2,LMNA,RPA2,GSTP1,IDH3A,SOD1,RPA3,PRDX6,POLDIP2,HSPA5,BCL6,CFL1,ATP5F1A,GLOD4,UBE2H,OAT,EIF4A3,ENO1,RPS3,ACAT1,RPS12,RPS20,PITPNB,BUB3,VIRMA,TP53,KBTBD4,CMPK1,ATP5PB,PGM1,GLRX5,TCIM,NHERF1,GPD2,SOD2,ATP5PF,RPL23A,CSE1L,HUWE1,H3C1,MPST,RPS13,OLA1,PMM2,ATP1B1,API5,RPS2,HDHD3,RPL12,LDLR,TMPO,ESD,NEK7,PPP1CB,ACAA2,AKR1A1,ARCN1,SLC25A3,MYL6,DDX39B,YAF2,HSPA8,TXNL1,HSCB,MYC,GGH,HMGCS1,AK3,CKB,MDH1,RPS5,RPS26,ATXN1L,RPS9,PRMT5,TENT5C,TUBB,AKR1C2,PSMD4,PRDX2,GNB1,CLIC4,CHCHD3,ACTN4,PDHA1,PIR,EZH2,RPS11,PABPC1,RPL31,HSPD1,RPS24,BAG2,RUVBL2,HINT2,RUVBL1,RPS27A,RPS4X,PIK3R1,PRDX1,CTNNB1,AGR2,AK2,GSTO1,RPL23,SIN3A,GATD3,TCP1,SUMO2,NUP35,DHX15,CACYBP |
| 1.025e-16 | -36.82 | RPS13 (ribosomal protein S13) | protein interactions | 6207 | 434 | 202 | 19454 | 5460 |
RPL31,KRAS,RPS4X,TRMT1L,PPIL3,MAGEB10,H1-3,SOX2,RPS7,KIF2A,RPL18,RPS23,RPS10,NOB1,DYNC1I2,RPL6,WWP2,XPO1,CPEB1,DDRGK1,DRG1,PYM1,RPS28,P4HA2,UFL1,STAU1,RPL27A,MTF1,FGF17,FBXO42,PAFAH1B1,PPT1,EIF4B,PIH1D1,CMTR1,SURF2,MATR3,RPL10,MYC,SFN,BTF3,RPS26,ICAM1,H1-1,RPL3,MEPCE,RPL17,IMP3,TP53,RPSA,TFCP2,RBM34,DNAJC2,DISC1,RPL32,FZR1,CAND1,RPS16,RPS27L,RBM42,SURF6,CMSS1,ENY2,COPS5,CD81,E4F1,TUBG1,RPL24,SNRNP70,RPS2,RPL10A,RPL27,BAP1,RNF113A,RPS15,HSPA5,CFTR,FGF13,RPA2,HEXIM1,KLF4,PSPC1,RPS3,PSMC5,FGFBP1,RPL10L,SMURF1,RPL7A,RPS17,EIF3G,SPOP,RC3H2,PDCD4,UBE2H,TRIP4,PPAN,RPS24,TNF,G3BP1,EMC8,TRIM37,RPS27A,SRSF4,RAD21,B3GNT2,EZH2,NGB,CHMP4C,RPS11,RPL9,FOLR1,RPL8,PHB1,RPLP2,RPLP1,NOP58,RPL7,PSMD3,MAP3K14,RB1CC1,AHSA1,RPL23,PSMC1,G3BP2,H1-5,WDR77,APOBEC3C,EMC9,FAU,RPL37A,SEC61B,RPS9,RPL7L1,RPL35,MAD2L2,RPL19,ACO2,CUL2,CUL3,ZNF668,RIOK2,RPS29,BRCA1,RPS5,RIT1,RPL23A,HUWE1,VRK1,FBP1,EEF1A1,RPL15,LLPH,ILF2,SRP72,EFNA3,RPL12,KRR1,RCHY1,PRR3,RPL35A,CDK9,NOP9,MOV10,EMC4,HDAC6,SPP1,PSMD7,RPA3,PNO1,NOG,DGCR8,RPL4,HMGB1,FBXW7,BRIX1,UTP23,RBFOX2,RPS14,CDK7,JUP,METTL14,GRM2,H2AC7,RPL26L1,RPLP0,MACROH2A2,HAUS2,CCNF,METAP2,PRKRA,RPS12,PTEN,RPS20,NDN,RHOJ,NREP,RPL13A,RPL22,RPL26,AR,TUFM,PPP1CC |
| 1.057e-16 | -36.79 | ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2) | protein interactions | 10425 | 314 | 157 | 19454 | 5460 |
DISC1,PCMTD2,ILF2,TP53,TNRC6C,RPSA,UBE2V1,RPL15,EEF1A1,HNRNPK,NEDD8,SNRPG,RPL17,RPS13,GLUL,NKRF,DHX9,RPL23A,RPL3,RPL24,SNRNP70,RPL10A,RPS2,TCEANC2,ELOC,APOBEC3F,DCUN1D1,RPS16,RPL35A,CAND1,MDM2,ALYREF,EIF4E2,UBE2N,SYNCRIP,EEF1B2,RPL12,ACACA,UBE2M,TFIP11,RPLP0,RPS14,WSB1,RPL4,BRIX1,HSPA5,UGP2,PML,SLC39A9,RPL27,H2BC12,DNAJC10,UBE2E3,IGF2BP1,NUDT1,RPL7A,RPL26,TIA1,RPS17,RPL13A,RPL22,UBB,UBE2L3,TUBA1B,SCAMP2,RPS3,ALB,RPS20,TRIM27,B4GALT1,RTRAF,TUBB4B,EZH2,RPL18,SNRPE,RPS23,SART3,TULP3,EEF2,PPP2R1A,GFI1,HNRNPF,PAX6,TFG,HNRNPDL,RPS4X,HNRNPA2B1,PABPC1,RPS24,RTCB,EWSR1,TRIM21,SLC39A7,UBE2D1,RPL23,HNRNPD,UBE2E2,RPL6,PRDX1,HNRNPA1,DYNC1I2,SNRPD3,RPL7,RPS10,RAB1B,AFAP1L2,DHX15,SRSF1,CBFB,RPL9,RPL8,KRT8,RPLP2,RPLP1,RNF7,CTBP1,APOBEC3C,RPL27A,ACTL6A,CDKN1A,PRDX3,EHD1,EEF1G,STAU1,SRSF2,TRA2B,UBE2D3,PTN,ASB3,RPS28,SNRPA,DR1,HSPA8,H1-10,CIRBP,CKB,CBR3,NLRP3,PHF7,RPS26,PYCARD,HNRNPAB,CUL3,SNRPB,RHEB,RBBP4,TUBB,APEX1,RPL10,RPL19,DLST,APOBEC3G,ARF1,PAPSS2,SNRPD1,PRMT5,SNRPD2 |
| 1.157e-16 | -36.70 | KARS1 (lysyl-tRNA synthetase 1) | protein interactions | 3735 | 359 | 174 | 19454 | 5460 |
HSPA5,MIR107,MIR29A,MARS1,BCL6,RAB9A,RNF113A,DLAT,BAP1,MIR10B,MIR21,HEXIM1,MIR7-1,SDCBP,RPA2,FGFR1,POLR1D,CDC42,MIR34B,SRC,GPX1,CTSB,PSPC1,UBE2H,MAT2A,CARS1,MIRLET7C,RPL17,MIR16-2,ABCE1,RAB27A,MRPS18B,MIR9-3,MIR200A,MAP1B,PSME1,FURIN,TFRC,RPSA,MIR429,CAND1,RPS16,MIRLET7G,CD274,COX4I1,MAP4,COPS5,GAPDH,DPP4,ANKMY2,UFL1,EMC1,STAU1,EEF1G,HSPA8,RAB5A,XRCC5,PIH1D1,FRS3,TOMM22,PAFAH1B1,BET1,PSMB6,ESR2,STAT1,MIRLET7B,LMBR1L,HMGCS1,MYC,KRAS,XPNPEP1,MIR155,SCPEP1,MIR206,PABPC1,CCT8,MOB3C,PDHA1,SOX2,TOP3B,RANBP1,COX14,HNRNPL,MIR9-1,SUMO2,CORO1C,MIR214,MIR221,MIR140,MIR31,MIR29C,DDRGK1,IFI16,SYNJ2BP,MIR143,WWP2,FBXW7,MIR7-3,MIRLET7I,MIR34C,RPA3,SOD1,MIR205,SIRT7,RARS1,MIR1-2,EEF1E1,VIRMA,CCNF,CTNNA1,NRP1,CDC73,PIP4K2C,MIR145,AR,HSD17B10,EMC2,FAF1,SFXN1,PPME1,RNF181,APEH,MIR20A,MIR15A,MIR200C,EEF1A1,AURKAIP1,FBP1,COMTD1,MDM2,PLGRKT,PLEKHF2,PSMB1,MIR25,HACD3,MIR106B,AIFM1,MIR34A,HDAC6,MIR106A,PSMA3,MED23,EMC9,PRDX3,MIRLET7D,RPL19,RANBP6,UBE2S,MIR363,RIT1,BRCA1,CUL2,RAB11A,PIK3R3,CUL3,EMC8,GTPBP1,VPS33A,CHMP4C,RAF1,E2F4,DHX15,SPTAN1,MIR141,ATP6V1A,PSMB5,MIR7-2,PHB1,MIR1-1,MED4,SKIC8,PSMD10,PPM1B,PRPF19 |
| 1.359e-16 | -36.53 | TARDBP (TAR DNA binding protein) | protein interactions | 23435 | 501 | 226 | 19454 | 5460 |
DDX50,RPL6,DDRGK1,CTNNB1,QPCTL,AGR2,FKBP4,DDX1,HSPB1,FUBP3,EED,ZHX1,HNRNPL,FAM98A,SNRPA1,TRMT61A,CHMP2A,TRMT1L,RANBP1,SOX2,H1-3,RPS7,EEF2,PDHA1,RHOBTB1,RPS23,RPL31,PABPC1,EWSR1,RUVBL2,TRIM11,KRAS,XPNPEP1,VDAC1,RPL28,RPS4X,HNRNPDL,MYC,HNRNPC,HNRNPAB,SFN,PSMD1,BTF3,CKB,H1-10,MDH1,DNAJB6,MATR3,APEX1,RPL10,MRPL12,ADSS2,MAP2K1,NUFIP2,RFC4,PYM1,DDX39B,XRCC5,HSPA8,SF3B1,DDX5,HNRNPA0,UFL1,ADRB2,PHB2,EEF1G,STAU1,DNAJB2,RBFOX3,ZFAND2B,GAPDH,SNRNP70,RPS2,MAP4,RPL10A,SYNCRIP,RPL32,FZR1,CAND1,RPS16,TMPO,IAH1,CDC5L,KBTBD4,CDK4,RPSA,SNIP1,RPL3,DHX9,HNRNPK,SRPRB,KPNA2,PSMB10,RPL17,SLC25A1,RPL7A,PRKACB,RPS17,GORASP2,SPOP,LSM6,UBE2E3,RC3H2,ELAVL2,UBE2H,RPS3,UQCRC2,PSMA6,RPP25,DYRK1A,SETD3,CFTR,RPA2,BAP1,PML,PGK1,LSM12,HNRNPH2,RNF113A,HSPA5,PRPF19,PDIA3,HNRNPA1,EMC6,HNRNPD,PPP3CA,RPL23,RPL9,RPL8,PHB1,NOP58,RPL7,CCAR2,PPIA,DHX15,RAF1,EZH2,CHMP4C,RPS11,RNF126,SLC25A5,HNRNPA2B1,SRSF7,BAG2,UBE3A,RPS24,SLC25A23,G3BP1,AP1M1,AHCYL1,SSRP1,NOP16,CUL2,CUL3,YWHAZ,BRCA1,HSP90AA1,CPSF1,TRMT6,ENO2,RPS9,ACTB,TUBB,RPL35,RPL19,PRRC2A,PSMA3,RNF10,NUBP2,NSFL1C,GPM6A,G3BP2,MOV10,GRSF1,HDAC6,ATP1B1,TFE3,RPL12,CTDSPL2,RB1,PWP2,TOP1,CDK9,CAV1,YTHDF2,MAP2K3,EEF1A1,RPL15,ILF2,GLUL,NKRF,ZC3H11A,RPL23A,HSD17B10,MRPL22,FBXO7,RPL26,ATP5F1A,AR,EPHA2,PLP1,CCNF,OPTN,TUBA1B,ENO1,RPS20,LDHA,RPL13A,RPL22,VIRMA,RPS14,ATG16L1,ARHGAP1,UQCRC1,CNP,JUP,MRPS34,METTL14,GRM2,RPLP0,SOD1,RPA3,SQSTM1,MTDH,USP8,RPL4 |
| 1.362e-16 | -36.53 | EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) | protein interactions | 1915 | 642 | 276 | 19454 | 5460 |
MTF1,ADSS2,CKS2,BMPR1A,SNRPA,HSPA8,COX17,YAF2,EP300,RAP2A,EEF1G,STAU1,ADRB2,MRPS7,MYC,CREBBP,SFN,GFUS,PSMA4,BTF3,PSMD1,BRMS1,RBBP8,LAMTOR1,PSMD14,SF3B4,MATR3,ATP5F1B,TRIM29,PSMD6,POLR2B,GADD45G,ESR2,EEF2,STMN2,CCR1,RPS23,RPL18,RPL31,PABPC1,RBM3,RUVBL2,RTCB,HNRNPF,PSMA2,PTPN4,KRAS,RUVBL1,VDAC1,RPS4X,HNRNPDL,PAEP,RPL6,ZCCHC10,YWHAH,YWHAG,AGR2,MGMT,CBL,POU5F1,DDX1,HSPB1,MAGOH,MAGED2,HNRNPL,SUMO2,UQCRH,GABRA1,NEK2,RPA2,SSR1,HEXIM1,UBE2M,STAT6,BAP1,EXOSC4,HSPB2,PGK1,RNF113A,ABCC2,HSPA5,RAB2A,CARS1,RPL7A,CFL1,GORASP2,RC3H2,UBE2H,PAFAH1B3,PSMA6,PHAX,ADRM1,RPL10L,SMURF1,UBL4A,RPSA,TP53,INSIG2,H2AX,TFCP2,PIK3CA,MAD2L1BP,RNF8,MAP1B,RPL3,RAB27A,NEDD8,HNRNPK,MEPCE,RPL17,MNAT1,KARS1,ZNF24,CD81,COPS5,GAPDH,ORMDL3,SMAD4,TUBG1,RPL24,H2AC4,TAF9,LSM3,RPS2,USP15,RPL10A,AQP2,SSBP1,EEF1B2,CAND1,RPS16,CDC5L,H1-5,ALKBH3,PPP1CB,CDKN1A,ANXA7,HTR1A,TXNL1,NMRAL1,CRY1,PSMA3,RNF10,ZDHHC17,PYGB,CUL3,CUL2,SAMHD1,RFC5,FAS,YWHAZ,HSP90AA1,RPS5,RIT1,HTRA2,RNF208,RSRC1,RAN,ENO2,AP2M1,POLR3B,SNRPD1,DYNLL1,TUBB,ACTB,MAD2L2,RAF1,B3GNT2,NEU1,PPP2R1A,LGR4,EZH2,POLR2C,RPS11,HSPD1,TRIP4,GADD45A,PCNA,RPS24,TRIM26,ZBTB16,TNF,TRIM37,HNRNPA1,MAP3K14,DDX23,TRAF6,AHSA1,BCL2L1,FOLR1,RPL9,PHB1,PSMB4,GJA1,PBDC1,XPO5,SDHAF2,RPLP1,HYPK,RPL7,CCAR2,KCTD10,CACYBP,RPS14,CCND1,TPT1,ARHGAP1,CDK7,JUP,H2AC7,PICALM,METTL14,RPLP0,SH3GLB2,CCL18,WTAP,MME,INPPL1,RPA3,PHYHIP,GTF2I,PDHB,TTR,FBXW7,RPL4,NUCKS1,PIK3R2,CTSD,RUNX1,ATP5F1A,TXNIP,SMAD2,CDC73,CCNF,CTNNA1,CTTN,EIF4A3,ACAT1,NDN,NREP,VIRMA,TBK1,SERPINB9,FBP1,TRIM6,EEF1A1,MLLT6,RPL15,GPX7,ILF2,ALPL,PPP4C,TOPORS,RAD23B,RAB1A,FAF1,PQBP1,RPL23A,HSD17B10,IGF1R,SEM1,HSPE1,THRAP3,RPS13,SMN1,MOV10,GMPPB,SPATS2L,HDAC6,CRADD,SPP1,RPL12,EFNA3,DCUN1D1,MDM2,CDK9 |
| 1.530e-16 | -36.42 | negative regulation of cell communication | biological process | GO:0010648 | 1485 | 579 | 18204 | 5365 |
TMEM196,SPRY1,PRNP,MIR449A,PPARA,TMBIM1,PAK5,GPR37L1,PPP2CB,ENO1,FAM89B,MIR1224,ERRFI1,MIR885,STAMBP,BAX,IL6,CSK,ABHD6,MMP9,PCDH17,ACAA2,MIR107,PYDC2,PADI2,GNAO1,FOXP1,YWHAG,MIR223,PEA15,ACVR1C,MIR185,BRAP,ELF1,MMP14,IL12B,UBE3A,MOSMO,MIR375,CPNE1,LILRA2,SYT4,MIR21,INHA,MIR519D,HADH,PPP1R10,TLR9,LEPROTL1,RGS10,HDAC3,SMURF1,GNAZ,PEBP1,HACD3,UBE2B,MCL1,SH2D1A,OPTN,MIR210,VPS18,UCN,TPT1,SLC35C1,ZNF592,NDUFS3,HHIP,TCF21,MAD2L2,SIN3A,SAR1B,MIR204,NMI,DUSP26,MIR99A,MIR92B,TLR6,SLC25A31,GPC1,DRD3,SDHAF2,TANK,SMAD4,GRB10,SELENOS,LMNA,ZMYND11,MIR1271,SLC6A1,HERC4,PPP3CA,AKT1,NOP53,MIOS,IL1B,TGFB3,SIAH2,TNFAIP3,CTNNB1,RBBP4,RGS5,BAK1,HYAL2,GSTP1,INPP5E,NPVF,KICS2,GPX1,IGF1,SAP30,NFKBIA,SNX5,UBE2W,ENY2,CNOT2,VDAC2,UCP2,SPRED1,TAX1BP3,CALR,BOK,SIRT7,CAAP1,ARRDC3,MIR221,MIR130A,MIRLET7B,UBE2N,CARTPT,UBE2D1,AR,RRN3,MIR497,NCOA5,AATF,ADRB3,XBP1,GRIA1,DLK2,HTRA1,MET,MIR206,GNAI2,PID1,CDK5RAP3,SYVN1,TMEM88,CRY1,GSK3A,DEFB114,PARL,BCL2L1,STXBP1,PTEN,TSG101,NR1H2,MIR125A,MIR573,STAT1,NRP1,RPGRIP1L,TSPAN15,PHB2,MIR140,PDE4B,WIF1,ATF4,THY1,INSIG2,SQSTM1,TNFAIP8L1,LEP,FAIM,KCNJ11,GTF2H2,RB1CC1,PBLD,DAG1,MIR34C,CDK20,SRC,SH3BP4,PDCD4,LGR4,MIR15A,PAFAH1B1,MIR34B,ICAM1,RGS7BP,TCIM,MIR218-1,OPRK1,NIBAN2,LMO3,CCDC3,CTNNBIP1,BPIFB1,MIR100,CUL3,NR0B1,PIK3R2,BRMS1,PRKACB,OSM,YWHAZ,RGS6,RNF115,SAMHD1,MIR29A,NF2,UBASH3B,LPXN,MIR874,PRRT1,FBXO7,NFE2L2,PRELID1,FGF23,PPM1B,CARD19,IVNS1ABP,NKX3-1,FBXW7,NFKBIL1,ATF3,PRR5L,FCGR2B,NOG,CREB3,STK11,STAP1,ADIPOR1,STK38,CCAR2,MIR205,CLU,BFAR,TXNDC12,CISH,TMBIM6,MINAR1,CCN3,TRIM32,TAF9,CRHBP,EGFL7,KBTBD6,DUSP1,LACRT,DDIT4L,LMBR1L,SARM1,MIR24-1,MIR101-1,KCTD10,DUSP22,SCYL2,GRM2,PICK1,CSNK1A1L,CYRIB,TRIB1,TBK1,PPIF,CD2AP,CD38,CTNND1,CLEC12B,DUSP9,MIR373,MIR222,FKTN,MIR16-1,TERT,DRD1,PIH1D1,OPRL1,NHERF1,DUSP6,MAPKAPK5,SOSTDC1,NUP62,PDE2A,BTN2A2,SOCS4,SMAD5,CSF2,USP15,HEY2,RNF34,OPRM1,STK3,FRZB,CYP26A1,MIF,MIR132,HTR2A,INPP5K,SCG2,IL12A,APLN,SNIP1,PELI3,MYC,IFT172,CSNK1E,IER3,IGF1R,FRMD8,FLCN,SFRP1,MIR302B,PPIA,MIR490,HSPB1,SOCS2,DUSP19,MIR142,CCL5,G3BP1,RGS19,KCNB1,PEG10,GLRA1,EPHA4,DYRK2,HCRT,DLX1,LRRC14,WWP2,UBAC2,CD46,FXN,MIR149,IGFBP3,RNF113A,TULP3,MTM1,MIR146A,PSEN1,LILRB4,BEND6,TMEM127,HTRA2,LDLRAD4,CNKSR3,SOCS5,HSPA5,MIR342,BRCA1,MAD2L1BP,VGLL4,CDKN2D,FKBP1B,TAX1BP1,GPR35,LYPLAL1,ING2,MSTN,CAV3,RUVBL2,DKK3,ACHE,SOCS3,CAV1,CPTP,TRIM11,MAVS,ISG15,DDIT4,MIR152,RNF167,GREM1,ADRB2,GCLC,PTPN22,SOX2,DKK1,DYRK1A,FGF10,SESN3,TLE1,SHISA2,SPRED2,OTUD7B,JAGN1,NCK1,MIR9-1,PAK1IP1,CHP1,TGFB2,DUSP3,MAP2K3,IL1A,CRYBA1,SNAI2,IFI35,DICER1,DNAJB9,BANF1,LITAF,SLC35F6,IGBP1,CHST11,DLG1,IL1R2,ARHGAP25,GHRL,MIR20A,CSNK2A1,CTNNA1,TNR,ANKRD6,SOX9,STAT2,CBL,SAP30L,PRKCB,HGS,CHGA,RNF126,IGFBP4,OAS1,MIR200C,ATP2B4,NLRP6,H2BC11,MIR29C,FKBP1A,KDM1A,TMEM170B,MIR708,CAV2,TMEM14A,PTPN11,NONO,SEC14L1,JADE1,GHITM,IFI6,TLR4,APLNR,DHRS3,EYA3,CER1,DDIT3,GABBR1,ITGAV,MIR340,ACKR3,PRDX2,PCGF2,MIR26B,NKIRAS1,PTPN1,ADORA1,HSPA8,ZNF451,TNFAIP6,ITGA6,SYNJ2BP,SOST,MIR1-1,AZI2,SOD2,MIR34A,UBE2D3,MIR133B,CXCL8,MDM2,LPAR1,RGS1,STK4,ARF1,TP53,UFL1,MIR503,PPARG,CSNK1A1,CCDC22,PAQR3,SFRP4,HELLS,TSPO,UFD1,SLA2,PRKCQ,SESN2,PPP2R1A,MIR106A,SUFU,HOMER3,MIR195,YTHDF2,LEMD3,FZD6,PYCR1,MIRLET7G,IL7,EZH2,LGALS3,NR4A2,SLC6A4,TPBG,EPO,EGR1,TRIM15,CNOT7,ARHGAP12,EMILIN1,MIR98,FBP1,HECW1,MIR361,PYCARD,MIR23A,DUSP10,CHRDL1,STUB1,ABHD17A,CXCL12,BCL6,EPHA2,CTDSPL2,PFDN5,MPIG6B,RGS2,SEC13,SLC25A4,MIR145,CX3CR1,PHB1,ING1,TWSG1,DDRGK1,TNF,ADIPOQ,LBH,RBBP7,BRMS1L,CX3CL1,RAF1,MUL1,NDUFAF2,IL10,PIP4K2C,MIRLET7C,IRF4,RHOH,GJA1,YWHAB,MIR17,MIR214,NLRP3,CASTOR2,EIF4E2,ACVR1,EID2,NKIRAS2,RNF152,CGAS,MIR424,TNFAIP1,TBC1D10C,ADNP,CITED1,RB1,CTTN,STRADB,GREM2,NLRP2,NPY5R,SLC25A5,PSMD10,INPPL1,ATAD1,TMSB4X,HAPSTR1,MDFI |
| 1.530e-16 | -36.42 | negative regulation of signaling | biological process | GO:0023057 | 1485 | 579 | 18204 | 5365 |
EIF4E2,CASTOR2,NLRP3,ACVR1,GJA1,YWHAB,MIR17,MIR214,RHOH,PIP4K2C,MIRLET7C,IRF4,HAPSTR1,TMSB4X,MDFI,INPPL1,PSMD10,ATAD1,MIR424,CGAS,TNFAIP1,TBC1D10C,CTTN,RB1,ADNP,CITED1,NPY5R,SLC25A5,NLRP2,STRADB,GREM2,EID2,RNF152,NKIRAS2,BCL6,CXCL12,PFDN5,CTDSPL2,EPHA2,RGS2,MPIG6B,STUB1,ABHD17A,PYCARD,MIR23A,MIR361,DUSP10,CHRDL1,ARHGAP12,MIR98,EMILIN1,HECW1,FBP1,CX3CL1,BRMS1L,RAF1,NDUFAF2,IL10,MUL1,TWSG1,DDRGK1,ADIPOQ,TNF,RBBP7,LBH,PHB1,ING1,SEC13,SLC25A4,CX3CR1,MIR145,PRKCQ,SLA2,PPP2R1A,MIR106A,SESN2,SUFU,HOMER3,HELLS,TSPO,UFD1,CSNK1A1,CCDC22,PAQR3,SFRP4,UFL1,PPARG,MIR503,EGR1,TRIM15,CNOT7,NR4A2,AP1AR,LGALS3,TPBG,EPO,SLC6A4,IL7,EZH2,FZD6,YTHDF2,MIR195,LEMD3,MIRLET7G,PYCR1,NKIRAS1,PTPN1,ADORA1,HSPA8,GABBR1,ITGAV,ACKR3,MIR340,PCGF2,PRDX2,MIR26B,SEC14L1,JADE1,NONO,GHITM,DHRS3,EYA3,IFI6,APLNR,TLR4,DDIT3,CER1,TMEM14A,PTPN11,STK4,ARF1,TP53,MIR133B,LPAR1,CXCL8,MDM2,RGS1,SOD2,MIR34A,UBE2D3,TNFAIP6,ZNF451,ITGA6,SOST,SYNJ2BP,AZI2,MIR1-1,TNR,CTNNA1,ANKRD6,SOX9,STAT2,CBL,IL1R2,ARHGAP25,GHRL,MIR20A,CSNK2A1,BANF1,DNAJB9,LITAF,IGBP1,SLC35F6,DLG1,CHST11,IFI35,SNAI2,DICER1,KDM1A,MIR708,CAV2,TMEM170B,ATP2B4,MIR200C,H2BC11,FKBP1A,MIR29C,NLRP6,IGFBP4,RNF126,OAS1,SAP30L,PRKCB,CHGA,HGS,DKK1,DYRK1A,GCLC,PTPN22,SOX2,RNF167,ADRB2,GREM1,DDIT4,ISG15,MIR152,MAP2K3,IL1A,DUSP3,TGFB2,CHP1,CRYBA1,PAK1IP1,TLE1,SHISA2,SPRED2,JAGN1,OTUD7B,NCK1,MIR9-1,FGF10,SESN3,MIR342,BRCA1,BEND6,HTRA2,TMEM127,CNKSR3,LDLRAD4,HSPA5,SOCS5,RNF113A,MIR146A,PSEN1,MTM1,TULP3,LILRB4,CD46,MIR149,FXN,IGFBP3,MAVS,ACHE,SOCS3,TRIM11,CAV1,CPTP,ING2,LYPLAL1,DKK3,RUVBL2,CAV3,MSTN,MAD2L1BP,CDKN2D,VGLL4,FKBP1B,TAX1BP1,INPP5K,HTR2A,MIR132,IL12A,SCG2,PELI3,SNIP1,APLN,FRZB,CYP26A1,MIF,RNF34,OPRM1,STK3,CSF2,BTN2A2,SOCS4,SMAD5,HEY2,USP15,EPHA4,DYRK2,LRRC14,WWP2,DLX1,UBAC2,RGS19,KCNB1,G3BP1,CCL5,PEG10,PPIA,HSPB1,MIR490,DUSP19,MIR142,SOCS2,MYC,CSNK1E,IFT172,IER3,SFRP1,MIR302B,FLCN,IGF1R,FRMD8,MIR373,FKTN,MIR222,CD38,CD2AP,CLEC12B,DUSP9,CTNND1,TRIB1,CYRIB,TBK1,PPIF,GRM2,PICK1,CSNK1A1L,MAPKAPK5,NUP62,SOSTDC1,PDE2A,NHERF1,DUSP6,OPRL1,MIR16-1,DRD1,PIH1D1,TERT,TXNDC12,CISH,TMBIM6,MINAR1,CLU,MIR205,BFAR,CREB3,STK11,STAP1,CCAR2,STK38,ADIPOR1,FBXW7,NKX3-1,ATF3,NFKBIL1,FCGR2B,NOG,PRR5L,MIR101-1,MIR24-1,KCTD10,DUSP22,SCYL2,LMBR1L,SARM1,KBTBD6,EGFL7,DUSP1,DDIT4L,LACRT,TRIM32,CCN3,TAF9,CRHBP,BRMS1,PRKACB,YWHAZ,OSM,CUL3,NR0B1,MIR100,PIK3R2,CTNNBIP1,BPIFB1,MIR218-1,OPRK1,NIBAN2,CCDC3,LMO3,PRELID1,FGF23,PPM1B,CARD19,IVNS1ABP,NFE2L2,FBXO7,RNF115,SAMHD1,NF2,MIR29A,MIR874,LPXN,UBASH3B,PRRT1,RGS6,CDK20,MIR34C,DAG1,SRC,SH3BP4,FAIM,GTF2H2,KCNJ11,PBLD,RB1CC1,PDE4B,MIR140,THY1,ATF4,WIF1,INSIG2,LEP,SQSTM1,TNFAIP8L1,PHB2,ICAM1,TCIM,RGS7BP,MIR34B,PAFAH1B1,LGR4,MIR15A,PDCD4,MIR206,PID1,GNAI2,AATF,ADRB3,XBP1,GRIA1,HTRA1,MET,DLK2,CARTPT,UBE2N,MIR497,RRN3,AR,UBE2D1,NCOA5,CAAP1,ARRDC3,MIR130A,MIR221,MIRLET7B,NR1H2,MIR125A,MIR573,STAT1,RPGRIP1L,PCSK9,NRP1,TSPAN15,BCL2L1,PTEN,STXBP1,TSG101,DEFB114,PARL,CDK5RAP3,SYVN1,CRY1,TMEM88,GSK3A,AKT1,MIOS,NOP53,TGFB3,SIAH2,IL1B,ZMYND11,LMNA,MIR1271,SLC6A1,PPP3CA,HERC4,SDHAF2,SLC25A31,DRD3,GPC1,SELENOS,TANK,SMAD4,GRB10,MIR99A,DUSP26,MIR92B,TLR6,BOK,CALR,TAX1BP3,SIRT7,NFKBIA,IGF1,SAP30,SNX5,VDAC2,CNOT2,UBE2W,ENY2,SPRED1,UCP2,NPVF,KICS2,INPP5E,GPX1,CTNNB1,RBBP4,TNFAIP3,RGS5,BAK1,GSTP1,HYAL2,PEBP1,UBE2B,HACD3,SH2D1A,MCL1,TLR9,LEPROTL1,HDAC3,RGS10,GNAZ,SMURF1,MIR21,INHA,MIR519D,HADH,PPP1R10,MIR375,CPNE1,LILRA2,SYT4,SAR1B,MIR204,NMI,MAD2L2,SIN3A,SLC35C1,ZNF592,TCF21,HHIP,NDUFS3,MIR210,OPTN,UCN,VPS18,TPT1,LDLR,ENO1,FAM89B,MIR1224,ERRFI1,MIR885,PPP2CB,PPARA,TMBIM1,GPR37L1,PAK5,SPRY1,TMEM196,PRNP,MIR449A,BRAP,MIR185,ELF1,IL12B,UBE3A,MMP14,MOSMO,FOXP1,YWHAG,PEA15,ACVR1C,MIR223,PYDC2,ACAA2,MIR107,MMP9,PCDH17,GNAO1,PADI2,BAX,STAMBP,IL6,ABHD6,CSK |
| 1.649e-16 | -36.34 | TRIM5 (tripartite motif containing 5) | protein interactions | 574288 | 297 | 150 | 19454 | 5460 |
RPS9,RAN,ARF1,FAU,NDUFAF4,RPL7L1,RPF1,UMPS,TUBB,TAB1,TAMM41,EIF4A2,RHEB,PYCR1,CFAP20,NIBAN2,ILK,MDH1,HSP90AA1,RPS26,RPS5,YWHAZ,BLVRA,EMG1,HSPA8,ATPAF2,DUSP9,PHB2,SERPINB6,IDH3B,MTX2,LAP3,ADSS2,ATP6V1A,PHB1,HDHD5,RPL8,RPL9,HSP90AB1,CCT7,NDUFS8,RPL7,SNX2,COPS7B,TRIM34,PPIB,YWHAH,XPO1,LRRC57,HAX1,TST,PDIA6,PCNA,HNRNPA2B1,BCKDK,FLOT1,RFC3,SAR1B,ANP32B,ADO,VDAC1,EEF2,ERLIN2,TUBA1A,FEN1,RPL18,EXOSC3,PTRH2,UCK2,NME1,SEC61G,TUBB4B,GNPDA1,PTPMT1,MACROH2A1,GANAB,SRP54,EIF4A3,RPS3,CPT2,RPL13A,LDHA,HPF1,MAGOHB,TUFM,PYCR2,GSTK1,PSMB2,PSMG3,CALU,CA2,OAT,NAPA,PIP4K2C,DCAF16,MRPS16,SPCS2,SQSTM1,IDH3A,PNO1,MAIP1,PIAS1,UBE2K,YKT6,PDHB,PCK2,SF3A1,MACROH2A2,RPLP0,SAMM50,IDH2,HSP90B1,MRPS34,TIMM23,RAP1B,UBE2N,RPL12,MIF,NKAP,RPS27L,RPL35A,NR2F6,ISYNA1,PGAM1,GMPPA,EMC4,RPS2,PSMG2,TUBG1,RAB13,FKBP8,CNOT6L,FASTKD5,CSE1L,IMP4,FN3KRP,RPL15,PGM1,EEF1A1,ACTR1A,GTPBP8,TRIM6,TBK1,H2AJ,SLC25A24,RAD23B,NUDT16,ILF2,NDUFS3,PCMTD2 |
| 1.713e-16 | -36.30 | PPT1 (palmitoyl-protein thioesterase 1) | protein interactions | 5538 | 241 | 128 | 19454 | 5460 |
TIMM13,TANK,KLC2,MYL6,VAPB,ATP5PO,HSPA8,G3BP2,NDUFS2,HSCB,EEF1G,MYC,HNRNPAB,DBH,LDHB,HSP90AA1,ELAVL4,CRMP1,CCT2,YWHAZ,SARM1,VDAC2,ENO2,CHP1,ATP5F1B,PRDX2,RBBP4,DYNLL1,ACTB,SOX2,PPP2R1A,EEF2,GNAQ,PLD3,RPN1,NME1,GDI2,PDHA1,RTCB,HSPD1,SLC25A5,HNRNPA2B1,CCT8,PABPC1,TFG,HNRNPF,VDAC1,RUVBL1,YWHAG,HNRNPA1,PRDX1,PDIA3,RPL6,DDX1,HSPB1,YWHAB,ARMC8,RPLP2,RPL9,PHB1,PPIA,EGLN3,LANCL1,HSP90AB1,CCT7,RPL7,SPTAN1,CCAR2,TCP1,SNRPD3,FTH1,SPTBN1,RPLP0,HNRNPH3,GSTP1,RPA2,HSP90B1,HNRNPH2,PGK1,DLAT,SEPTIN6,BAP1,HSPA5,GTF2I,PDHB,ATP5F1A,CTSD,SLC25A1,RPL7A,ATP1A1,DNAJC10,RTRAF,RPS20,RPS12,CCNF,RPS3,ENO1,PSMA6,RPL22,LDHA,SLC25A4,ACTR1A,MTCH2,CCT5,NDUFS3,SEPTIN7,RPL23A,DHX9,MAP1B,TCOF1,CTNND1,RPS13,PRDX4,ERLEC1,HUWE1,HNRNPK,GAPDH,MICB,ISYNA1,RPS2,RPL10A,NME2,RPL12,UBE2N,ACTA2,DBT,CAND1,SCG2 |
| 1.955e-16 | -36.17 | CYLD (CYLD lysine 63 deubiquitinase) | protein interactions | 1540 | 847 | 346 | 19454 | 5460 |
CAPZA1,TMEM33,RPL3,TAB2,PSMC3,TFRC,CD209,NFE2L2,ACTR1A,MRPL47,IPO8,TNRC6C,CDC5L,SLAIN2,RPS16,SYNCRIP,EEF1B2,RPS2,USP15,RPL10A,TUBG1,BECN1,KLHL22,KARS1,DNAJB2,RBM17,EIF4E,TOMM20,HSPA5,MARS1,HNRNPH2,CLIP3,SPTBN1,ROCK1,EIF2S2,PSMC5,RPS3,PSMA6,ATP1A1,SNX5,EIF3G,RPS17,MAT2A,RPL28,HNRNPDL,ZNF609,RUVBL2,RPAP3,ACTR1B,PDIA6,RTCB,PABPC1,CCT8,RPL18,CRKL,PNMA2,TRAF2,LANCL1,EIF2S1,TCP1,MAGED2,S100A8,FABP5,SRSF1,SDC4,DRG1,YWHAB,HSPB1,PPIB,RNF41,STAU1,SPATA2L,HSPA8,LCN1,RFC4,XRCC5,MRPS18A,RPL27A,PSMD4,ATP5F1B,TIMM21,PSMD6,FBXO22,SF3B4,DNAJB6,H1-10,MRPL22,RPS13,EIF3E,MSH6,THRAP3,ILF2,MRPL49,RPL15,TBK1,YTHDF2,MRPL11,G6PD,PRNP,ETV6,SRP14,AIFM1,SLC2A1,CRBN,HDAC6,PFKFB2,RPL4,MAVS,SQSTM1,H2BC12,MTDH,LMNA,JUP,PSMC4,RPS14,SNRPN,RPL22,RPL13A,GSK3A,ACAT1,RPS20,STUB1,OPTN,IVNS1ABP,ATP5F1A,NONO,TUFM,CSK,SEC13,RFC3,G3BP1,KCTD17,JAK1,RPS24,CDKN2C,VPS33A,ACO1,CNTROB,CACYBP,SNX2,SPTAN1,RPL7,CCAR2,HP1BP3,RPLP1,MYEF2,PHB1,LYZ,RPL23,CSTA,TRAF6,EIF3D,PSMD3,PRPF19,PRDX1,RAB3D,PSMC1,G3BP2,UNC45A,NSFL1C,PDP2,WDR77,SNRPB2,RPL19,SPINDOC,RPL35,RBBP4,AP2M1,RPL37A,FAU,RAN,UBE2S,EIF3K,MYO6,RFC5,USP13,CUL2,CUL3,RPL17,HNRNPK,CSE1L,DHX9,MAP1B,MYD88,CAPZA2,FGL2,TP53,RPSA,MYL12A,FZR1,ALYREF,RPL32,MAP4,GAPDH,RPS15,STK38,PGK1,RPL27,HBB,AGO1,DYRK1A,TRAF7,CALML5,SEC61A1,SF3B6,MID1IP1,CFL1,PSMB2,AKT1,RPL7A,RPS4X,PSMA1,HNRNPF,ROCK2,TRIM21,MYO1B,RPL31,RPS23,TUBB4B,TUBA1A,RPS7,EEF2,DHX38,CCT7,HSP90AB1,HNRNPL,RPS10,SNRPD3,SNRPA1,PABPC1L,YWHAG,XPO1,YWHAH,SPATA2,CTNNB1,RPL6,TRA2B,PHB2,EEF1G,SF3B1,DDX5,DDX39B,EIF4B,MRPL12,PSMB6,ACAP2,RPL10,MATR3,TNFRSF9,PRMT5,MRPL13,DLG4,DLST,RPS26,SERPINH1,CCT2,PSMD14,PSMD1,PSMA4,HNRNPC,HNRNPAB,SFN,RIGI,HUWE1,FARSA,RPL23A,GARRE1,MLLT11,CCT5,RPL35A,PSMB1,RPL12,CNN3,GRSF1,SPATS2L,MRPL20,MRPL17,NF2,FBXW7,GRIA2,MEST,KRT7,RARS1,SF3A1,VIRMA,COPE,RPS12,SPIN3,ALB,ODR4,ENO1,COL1A2,MAPRE1,HERC4,STK38L,RPS27A,FOXP4,TNF,PCNA,BAG2,SLC25A5,ZYX,HSPD1,RPS11,SKA3,RPL29,ERLIN2,EGLN3,DHX15,RPLP2,KRT8,RPL9,RPL8,PSMB5,MED4,HNRNPD,MRPL18,PPM1B,HNRNPA1,CDSN,AZGP1,HSCB,BIRC2,PSMA3,ARCN1,SLC25A3,ATAT1,ERH,PRRC2A,PRDX2,EIF4A2,ACTB,TAB1,LGALS3,TUBB,SNRPD1,SNRPD2,RPS9,GRIA1,RPS5,HSP90AA1,ILK,YWHAZ,PRPF31,MRPL16,RPS29 |
| 1.989e-16 | -36.15 | SRRM2 (serine/arginine repetitive matrix 2) | protein interactions | 23524 | 428 | 199 | 19454 | 5460 |
FOLR1,BRD9,DHX15,PRPF19,HNRNPA1,TRA2A,DDX23,RSBN1L,HSPD1,TRIP4,HNRNPA2B1,BAG2,SRSF7,DHX16,TRIM26,SRSF4,MCM6,SSRP1,SF3B5,POLR2C,SNRPD2,SNRPD1,RBBP4,SNRPB2,ACO2,DSN1,CUL3,CFAP20,DCAF4,LMNB1,MYO6,RPS5,ILK,NKAPD1,NUP50,PSMC1,MTX2,DET1,LARP4B,MYL6,SRP14,PRNP,TOP1,DBT,AKAP17A,CDK9,MRPS23,BAK1,HDAC6,ZMYND11,BRD3,SEPTIN7,HAPSTR1,RPS13,RIGI,HINFP,CCT5,EEF1A1,CD2BP2,PPP4C,ILF2,CCNF,EIF4A3,GSK3A,NDN,VIRMA,RPL22,DHPS,CIAO1,DNAJC8,PPP1CC,NONO,CDC73,MAPRE1,RPA3,PPM1G,SIRT7,NOG,CLK1,SQSTM1,GTF2I,NF2,PDHB,PFKFB2,HMGB1,MBD3,PIAS1,AATF,SF3A1,PSMC4,DENND2D,LMNA,ZCCHC17,HNRNPH3,CLK4,SRSF1,EED,PAIP1,HNRNPL,SUMO2,DYNC1I2,SNRPA1,LYAR,SNRPD3,IFI16,BAZ1B,DDX50,WWP2,RPL6,ZCCHC10,YWHAH,YWHAG,CTNNB1,DDRGK1,DDX1,HSPB1,YWHAB,MAGOH,PABPC1,RUVBL2,SREK1IP1,HNRNPF,PTPN4,KRAS,DNAJC25,RPS7,NFKBIL1,HDAC11,MTA2,ZRANB2,CMTR1,SF3B4,SNRNP40,RPL10,ESR2,MYC,SFN,HNRNPC,BTF3,SNRPB,COP1,THOC6,PYM1,SLU7,DDX39B,SNRPA,HSPA8,SF3B1,EP300,DDX5,UFL1,TRA2B,SAP18,PABPC5,PAFAH1B1,MRPL12,CTBP1,PIH1D1,EEF1B2,SYNCRIP,ITK,ALYREF,CAND1,DNAJC1,FZR1,NKAP,TMPO,CDC5L,COPS5,CSNK2A1,API5,CHCHD1,SNRNP70,CDK12,RPS2,SNIP1,MAP1B,ABCE1,DHX9,CAMKV,HNRNPK,WBP11,CBX3,NUPR1,PSMC5,SRPK2,RPL7A,SUB1,ELAVL2,ATP1A1,UBE2H,RBM7,BAP1,NLE1,RNF113A,HSPA5,SPTBN1,RPA2,DYRK2 |
| 2.003e-16 | -36.15 | TNIP1 (TNFAIP3 interacting protein 1) | protein interactions | 10318 | 1189 | 460 | 19454 | 5460 |
SDC2,CD59,EHHADH,TANK,RPL27A,HNRNPA0,HSPA8,XRCC5,SNRPA,NSA2,POLR1B,H1-10,FTSJ3,RPL39,PHF21A,ZNHIT6,NFKBIA,EFHD2,RPL18,MTA2,CAAP1,SMNDC1,KIF2A,TRAF2,POLDIP3,RPL28,SREK1IP1,RTCB,CCT8,PABPC1,HSPB1,IKBKB,PPIB,SHC3,MRPL9,RIOX2,MDFI,LANCL1,LRRC61,LYAR,TCP1,TRIR,EIF2S1,MAGED2,NRSN1,S100A8,CORO1C,SRSF1,FBXO31,FABP5,GIT2,UTP15,ZNF326,H2BC11,SDCBP,SPTBN1,HSPA5,MARS1,KDM1A,BANF1,CORO6,RRP7A,ATP1A1,RPS17,MORF4L1,TNFAIP3,MAT2A,TRAF1,BUB3,EIF2S2,ING2,LIG3,RPS3,TAF2,RNF8,GRAP2,IK,MRPL36,TFCP2,ACTR1A,TNRC6C,ZNHIT1,CAPZA1,RBCK1,IMP4,KPNA2,MRPS18B,RPL3,RAB13,SLC16A1,TCEA2,ZBTB25,SLC25A11,SNIP1,RPL10A,RPS2,TMA16,RBM17,TCEANC2,CMSS1,KARS1,CDC5L,DKC1,RPS16,GTF2B,SYNCRIP,MYL6,PCLAF,ATP5PO,KRTAP8-1,PPP1CB,H1-5,G3BP2,UNC45A,GPC1,TSR3,CCDC86,HADHA,UPF3B,MAGEH1,MYO6,LMNB1,MCM3,MCM4,RIOK2,NOP16,GNB1,SNRPB2,RPL19,RPL7L1,RPL35,AP2M1,RPL37A,RAN,PARP2,CPSF1,MOXD1,GFPT1,FEN1,MCM6,UNC119B,AP1M1,LAMB2,G3BP1,RBBP7,RPS24,ARGLU1,RPL23,LYZ,TRAF6,DDX23,CSTA,CDIP1,PRPF19,PRDX1,ZNF593,KCTD10,SPTAN1,RPL7,NOP58,RPLP1,HP1BP3,TSG101,THOC2,RPLP0,NOL7,HSP90B1,H2AC7,LMNA,JUP,SNRPN,MYL12B,FAM161A,RPS14,GABARAP,AATF,NUCKS1,SMC4,RPL4,EIF5B,GTF2I,SQSTM1,H2BC12,ARPC2,CA2,PIP4K2C,NONO,TUFM,ATP5F1A,CTSD,RPL22,TXN,ABHD17A,LDHA,RPS20,GANAB,LURAP1,EIF4A3,OPTN,SRP72,APEH,ILF2,GGCT,RPL15,MAP1LC3B,DDX39A,EEF1A1,TBK1,MDC1,RPS13,MRPL22,ARF4,THRAP3,PAK1IP1,PC,ZNF787,SSX2IP,MPHOSPH10,MPG,CRHBP,CALR,NFKB1,SLC25A12,AKAP17A,TOP1,PPP1R18,UBP1,H2AZ1,SRP14,CSNK1A1,TRMT112,NUFIP2,EIF4B,GPC4,ZC3H14,USP6NL,PHB2,EEF1G,FXR2,TRA2B,DDX5,SF3B1,SPECC1L,RPS28,DDX39B,SERPINH1,RPS26,PSMD14,RPS6KA4,H2AZ2,CCT2,SNRPB,BTF3,ATG101,LDHB,HNRNPC,HNRNPAB,RPL10,POLR2B,TAX1BP1,MATR3,PRMT5,VDAC2,MOB3C,RPS23,TUBB4B,RPS7,EEF2,H1-3,RAB18,RAB8B,PRPS1,RPS4X,HNRNPF,FAM168A,TRIM21,EWSR1,MYO1B,ABCF1,S100B,RPL31,AVL9,CDC23,TNNC2,DDX1,ARHGAP5,SPATA2,EXOC1,NGDN,TENM3,XPO1,PTDSS1,SEC61A2,RPL6,DDX50,IFI16,CCT7,HSP90AB1,SNRPD3,SUMO2,HNRNPL,RAB1B,COCH,NOB1,KLF4,LUC7L3,TFB1M,HBB,SSR1,WDR3,RPS15,LITAF,RPL27,DDX46,IGF2BP1,PDCD4,CFL1,RPL7A,SMARCA5,MLF1,SLC25A1,CDC20,MACROH2A1,RBMX2,CALML5,SEC61A1,UQCRC2,GNAI3,CAPZA2,RP9,RPSA,RPL17,MEPCE,HNRNPK,CSE1L,H3C1,DHX9,MYD88,MAP4,NOL12,RPL24,BCL10,GAPDH,TPM3,RPS27L,ALYREF,RPL32,SSBP1,SLC25A3,CDKN1A,AZGP1,CMAS,RNF11,CDSN,CSRP1,NOP53,MRPL57,EMG1,RABAC1,BIRC2,RPS5,SCFD1,HSP90AA1,YWHAZ,RPS29,OPRM1,ACO2,ERH,ACTB,TUBB,PRDX2,ZMAT2,RPS9,SEC61B,SNRPD1,SNRPD2,GNG12,AVPI1,RPS11,STX12,RPN1,RPL29,MAPK10,ACTN4,GABARAPL1,BUD23,SSRP1,FLOT1,RPS27A,ASF1A,TNF,BAG2,HNRNPA2B1,SLC25A5,HSPD1,RB1CC1,NAB2,HNRNPD,ZNF207,HNRNPA1,NDC80,PIK3R1,HMGA1,DHX15,PPIA,AGK,NDNF,KRT8,RPLP2,BRD9,MAP1LC3A,RPL9,RPL8,WTAP,RARS1,RPL26L1,ZCCHC17,GABARAPL2,UQCRC1,UBA52,SF3A1,BRIX1,VPS28,UTP23,NF2,NRP1,AP2A1,RACGAP1,RPL26,CEP97,DEK,PNP,TMOD3,RPS12,MSN,TUBA1B,CTTN,CTNNA1,ENO1,EIF2AK2,ACTR2,LLPH,FCF1,MAP2K3,CCT5,H2AJ,RNF115,RPL23A,TCOF1,NKRF,PPP1R12A,FAF1,RAB1A,FAM133B,H2AC14,ERCC3,MOV10,RPL35A,ACTA2,RPL12 |
| 2.042e-16 | -36.13 | Infectious disease | REACTOME pathways | R-HSA-5663205 | 388 | 198 | 10285 | 3229 |
SSRP1,VAMP1,RPS16,ERCC3,TAF11,EEF2,RPL6,RPS20,PSMA6,GTF2H4,VPS4A,RPL35A,VTA1,NCBP2,SEM1,PSMB4,RPS13,RPL10L,RPS27A,RPS29,PSMC3,RPL18,RPL9,STX1A,SNAP25,ARF1,PSMB3,CD247,RPL35,AP2A1,CCNH,PSMA5,RPL17,TAF2,PPIA,SRC,KPNA1,RPL29,RPL10A,UBA52,RPL27,RPS12,GTF2A2,POLR2G,RPL4,SUPT4H1,TAF7,TAF10,RPS23,KPNA2,RPL32,FAU,CD4,NUP107,AP2M1,POLR2I,RPS14,SYT2,RPL24,AP2S1,CHMP2B,RPS26,RPS17,GTF2E1,PSMD6,RPLP2,HBEGF,RPL8,PSME2,CHMP2A,NUP35,RPLP0,PSMB5,PSMA3,CTNND1,APOBEC3G,PSMD3,DNAJC3,PSMB7,CPSF4,CD28,RPL19,PSMC5,PSMB10,B2M,BANF1,GTF2A1,PSMD7,RPS27L,RPS10,SKP1,RPL23,AP1M1,CBL,GTF2H2,ELOC,RPS24,PSMC1,GTF2B,CCR5,MAP2K6,FURIN,CDK9,RPL23A,VAMP2,RPL28,HSP90AA1,NUP42,PSMB2,PSMD1,POLR2C,TSG101,HMGA1,SV2B,VPS4B,RPL15,NUP62,RPS28,PAK2,RPS5,PSMD4,GTF2H5,CD9,TAF9,PSMA1,RPLP1,AP1S2,RPL13A,CTNNB1,ISG15,HSP90AB1,CHMP5,RPL10,RPL22,TXNRD1,MET,SLC25A4,RPS3,POLR2B,RPL26,RPS7,MNAT1,RPL39,PSMD10,TCEA1,RPL37A,RPL7,MAP2K1,GTF2F2,PSMD12,RPL3,CALR,SLC25A5,XRCC5,RPSA,EIF2AK2,VPS28,RAN,NUP37,GRSF1,XPO1,RPL7A,GTF2F1,FEN1,HGS,CHMP4C,SUPT5H,PSMB9,NUP153,RPL27A,RPS4X,RPL31,PSMC4,CXCR4,PSMB1,NUP50,RPL12,RPL26L1,PSMA2,PSMB6,PSMB11,PSMA4,MAP2K3,CBLL1,ELMO1,RPS15,CDK7,PSME1,GTF2E2,UBB,RANBP1,POLR2D,POLR2L,RPS9,RPS2,RPS11,PSMD14,POLR2F |
| 2.178e-16 | -36.06 | BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase) | protein interactions | 8945 | 745 | 311 | 19454 | 5460 |
XRCC5,HERC3,HSPA8,RAB5A,EP300,DDX5,RTL9,HNRNPA0,UBE2D3,TRA2B,EEF1G,SAP18,RPL27A,SUFU,MRPL12,MRPS18A,HBE1,MAP2K1,NUFIP2,CSNK1A1,DDIT4,NFKBIA,NFKBIB,BST2,MATR3,ATP5F1B,PSMD4,TRIM29,POLR2B,RPL10,APEX1,COPS7A,MYC,HNRNPAB,LDHB,HNRNPC,UFD1,PCCB,CCT2,FTSJ3,FBXW11,RPS26,RPL31,CCT8,PABPC1,TOP2B,TRIM21,EWSR1,RTCB,PDIA6,FAM168A,HNRNPF,KRAS,ZNF609,FOXN2,RPS4X,PFDN1,HNRNPDL,NFE2,POLDIP3,NAA16,DHX38,TUBA1A,RPS7,TUBB4B,ZRANB2,GHR,BTG1,RPS23,CSTPP1,FABP5,RBM5,SRSF1,S100A8,EED,FAM98A,HNRNPL,RPS10,MITF,HSP90AB1,CCT7,CNOT2,DIRAS2,PFDN5,RPL6,YWHAG,STK4,CTNNB1,CENPW,TBC1D10C,IKBKB,DDX1,HSPB1,YWHAB,LSM12,SMG5,OIP5,MRPL41,MRPL40,HSPA5,CLU,PAQR3,WSB1,RPRD1B,BTG2,ACACA,TRIM36,RPS3,UQCRC2,CSNK2B,EIF2S2,HEY2,TXNDC12,CDC20,SMURF1,DYRK1A,TRIM32,AKT1,CCNB1,ATF4,RPL7A,RPS17,CHPF,PDCD4,PTTG1,IGF2BP1,CALU,PALM2AKAP2,BHLHE40,CELF6,RPL3,DHX9,NEDD8,TGFBR2,HNRNPK,RPL17,MRPL47,TP53,NFE2L2,TBC1D4,CD274,SYNCRIP,ALYREF,RNF128,MCL1,CAND1,RPS16,FZR1,DKC1,MXI1,GPRASP2,ELOC,SMAD4,BCL10,SNRNP70,RPL24,NOS1AP,KPNA1,RPS2,USP15,TSPAN15,ATP5MK,TXNL1,CRY1,EMG1,PSMA3,NSFL1C,YTHDF1,G3BP2,SKP1,ATP5PO,RNF7,S100A6,RAN,RPL37A,RPS9,PRDX2,TUBB,ACTB,UBTD1,PRRC2A,RPL19,ERH,BTG3,TAFAZZIN,ELMO2,YWHAZ,HSP90AA1,PFDN2,SP1,PFDN4,RPS5,NLRP3,PFDN6,FAM219A,HSPD1,SLC25A5,HNRNPA2B1,ARGLU1,GADD45A,SLC39A7,RPS24,BAG2,SRSF8,SRSF7,TNF,G3BP1,ASF1A,COPS4,HSDL2,E2F4,ZNF704,NUP153,NFE2L1,EZH2,POLR2C,RPS11,RPL8,RPLP1,RPLP2,TNFAIP8L2,COPS7B,RPL7,SRSF10,STK3,DHX15,PRDX1,CLPX,PDIA3,MAP1S,MRPS35,HNRNPA1,TRA2A,UBE2D1,WDR12,HNRNPD,VCPIP1,LYZ,RPL23,PPM1G,FLCN,MTDH,RPL4,MBD3,AATF,RBFOX2,CCND1,MYL12B,UQCRC1,CDK1,MRPS34,JUP,HNRNPH3,RPLP0,WTAP,CCNF,STUB1,ENO1,CTNNA1,TUBA1B,EIF4A3,CTTN,RTRAF,GANAB,PRKRA,ALB,RPS20,TXN,RPL13A,PHTF2,SFRP4,CEP97,ATP5F1A,RPL26,NONO,IFNAR1,SH3BP5L,CCDC22,FAF1,TCOF1,DLG1,RPL23A,PC,HINT1,LSM4,TCP11L2,FARSA,THRAP3,FN3KRP,CTNND1,RPS13,TBK1,YTHDF2,CCT5,EEF1A1,RPL15,SOX9,ILF2,MRPL49,MSRB3,SMAD3,HRAS,TFE3,RPL35A,MDM2,PLGRKT,MRPL24,MOV10,NFKB1,TIAM1,SSX2IP |
| 2.385e-16 | -35.97 | RPL7A (ribosomal protein L7a) | protein interactions | 6130 | 593 | 258 | 19454 | 5460 |
ENY2,RPL24,SNRNP70,RPL10A,RPS2,NOL12,RPL32,EEF1B2,RPS27L,SPPL3,FZR1,RPS16,DNAJC1,SURF6,CDC5L,TMPO,RBM42,DKC1,LMAN1,RPSA,TP53,KBTBD4,IMP3,UBL4A,H2AX,DNAJC2,RBM34,TFCP2,MRPL52,SNIP1,RPL3,IMP4,RPL17,MEPCE,RPF2,ZSCAN25,H2BC9,TRIM23,RC3H2,MRPS16,MECP2,UBE2H,ZNF330,RPS3,PSPC1,RBMX2,PHAX,RPL10L,RSL24D1,SRPK2,SMYD3,CFTR,SSR1,RPA2,ZNF770,UBE2M,HEXIM1,DYRK2,PML,NLE1,BAP1,RPL27,RNF113A,H2AC13,RPS15,HSPA5,RPL6,WWP2,DDX50,IFI16,NGDN,DDRGK1,CTNNB1,XPO1,AGR2,H2BC17,MAGOH,DRG1,PEX3,SRSF1,RAB35,EED,RPS10,EIF2S1,FHIP1B,HSP90AB1,RPS7,MSX2,EEF2,DNAJC25,GLE1,RPL18,RPS23,PABPC1,RPL31,EWSR1,H1-6,RPL28,RPS4X,SFN,MYC,BTF3,H1-10,ATG3,FTSJ3,MRPS25,H1-1,NSA2,COP1,ICAM1,RPS26,CMTR1,ZNF189,ZHX3,SNRNP40,ZCCHC7,TAX1BP1,MATR3,APEX1,RPL10,FBXO42,PAFAH1B1,MTF1,RPL27A,MRPL12,PPT1,MAP2K1,PIH1D1,RPS28,HDAC5,HSPA8,STAU1,UFL1,EMC4,SPATS2L,MOV10,APOBEC3F,HDAC6,MPHOSPH10,ACTA2,KRR1,RCHY1,RPL12,PSMB1,RPL35A,CDK9,FBP1,CCDC47,RPL15,FCF1,TAF1D,EEF1A1,SOCS3,LLPH,SRP72,RNF181,ILF2,NKRF,FAF1,RPL23A,VRK1,HUWE1,PAK1IP1,RPS13,PPP1CC,DNAJC8,RPL26,DNAJC19,METAP2,EIF4A3,CCNF,RPS12,RPS20,GSK3A,PRKRA,RPL13A,NDN,RPL22,EEF1E1,RPS14,ATG16L1,CDK7,METTL14,MACROH2A2,ZNF574,RPLP0,RPL26L1,SIRT7,RPA3,MTDH,KIN,HMGB1,FBXW7,RPL4,DGCR8,BRIX1,AATF,PIAS1,MAP3K14,KDM2A,DICER1,RPL23,RSBN1L,PHB1,RPL9,FOLR1,RPL8,RPLP2,RPLP1,RPL7,CACYBP,B3GNT2,RPL29,MAK16,OTUD6B,CHMP4C,EZH2,SART3,MTMR2,RPS11,TRIP4,SLC25A5,RPS24,TRIM37,G3BP1,TNF,TRIM26,RBBP7,RPS27A,NOP16,CUL3,ZNF668,DCAF4,ZCRB1,BRCA1,RHOB,FYTTD1,RIT1,RPS5,ZNF22,SEC61B,RPS9,RPL37A,LGALS3,RPL35,RPL7L1,RPF1,RPL19,WDR77,EMC9,PPARG,APOBEC3C,NMRAL1,NOP53,MRPL57,GPC1,G3BP2,COIL |
| 2.477e-16 | -35.93 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 15798 | 4649 | 16828 | 4835 |
BOLA1,GGCX,PAQR4,ELOF1,CCAR1,NTRK3,PICK1,TSSK1B,PDIA2,RNF146,SAP30L,FAM76B,SNAP23,OR4N2,STAC3,FAM3A,MNAT1,TNFSF10,FMO3,CDK5RAP3,NEK9,CLDN6,CAPZA1,STX1A,AGAP2,GUK1,FBXO3,IRF2BP1,CSE1L,UBE2B,ACHE,PI15,HECTD3,FABP12,FGL2,HDAC5,RPL17,UBL4A,SERPINB11,GKAP1,GAPDH,SLC25A42,VAC14,CLIP3,CBLN3,CRYGA,GRIA1,YES1,NXT1,SLC35C1,RLN3,ANKRD50,NEO1,HSD17B3,PCCB,ESAM,MFSD6,POU3F4,MADCAM1,ASRGL1,MPST,PSMC4,RFC5,JRKL,IDH3A,TMEM97,NSDHL,MED13L,KLHL23,HSDL1,ACOT6,IL12B,WDR6,NCALD,ANGPT1,COPS4,KCNK17,ZGLP1,DEFB124,INSIG2,LHB,CBL,MRPS35,ATP6V1G2,RAB6B,MMP14,DDI1,RAB28,COX17,ELK1,FAM168B,CYP1B1,MDH1,MRAS,RALYL,MRPL41,FGF7,MAPRE2,CAV3,EPHA2,PRPF18,IGSF21,CDK2AP2,SRSF1,SLC31A1,DIO3,COX6B1,ITGA2,UCK2,LMBRD1,EXOSC8,ZNF574,KLHDC8A,KDM2A,POLD2,SUMO1,DCLRE1C,OR10G3,OR2J3,G3BP2,IFT52,ACOX1,F7,FADS2,PIK3R1,TSPAN7,CBX7,COL3A1,PAK1IP1,VAMP1,ADRB2,GPN2,TLR4,SLC6A1,QSER1,SLC2A1,MYO1B,GPT,SRSF12,CTTNBP2NL,VDR,IL5,PTGDS,PEBP1,ADRA1A,TNNI1,CX3CL1,FGF22,PSMB2,PRR19,ANO3,UBE2N,NGDN,CTRB2,CCL1,PSKH1,STX16,FKBP4,EIF5A2,PI3,SMURF1,DPPA2,PMP2,P2RY10,NKX6-2,GPR22,PLAC9,SLC38A2,HS3ST5,PFDN1,SSR3,LIN7C,SGMS2,ANXA7,NCSTN,TAF2,CNOT7,ADRM1,RABIF,CD80,EMX1,PKIB,UBTD2,IREB2,TAF11,CDC5L,LGI1,SLC35A5,TMEM19,OR2F1,CH25H,HPS6,TCP1,KCNH8,CRMP1,RUVBL2,GOSR1,IGF2BP1,NCOA5,MMAA,PPIC,ARMC6,CHCHD1,SIKE1,NDN,SNX3,DBH,CLRN1,TBC1D5,USP46,SMAD2,PITPNB,LPAR6,POLR2C,GNAQ,RAD1,GIPC3,NGRN,DBNDD1,NFE2L2,CCDC167,HSP90B1,PSMB11,TCOF1,LRAT,EDDM3B,ZDHHC8,ISOC1,RETN,MCPH1,NKRF,GATAD1,RGS10,PTGES3,ACTN4,RPS15,ASB1,QRSL1,VIPR1,FBXL3,CXCL9,RBPJ,MRPL17,DUSP9,CFDP1,SIGMAR1,IFNK,ATP2B4,EGLN2,KLHL28,EDEM3,TPPP2,RNF152,UQCRC2,MRPL33,LRRTM1,LYZL4,CST3,PLEKHO2,ICA1,BCL2L1,YWHAG,ACVR1,VDAC2,DCTN6,MYH1,IFT57,PPP1CC,PAQR8,PEX26,BAZ1B,OR4E2,OR7D4,KCNB1,TNFRSF9,ZNF32,NOP16,DMAP1,LRRC8C,EAF2,ADH1A,DCK,ITM2A,MCM6,RPS24,NUDT4,DCUN1D1,CYP7A1,DIRAS1,PRRT1,ABCE1,GINS4,SDS,SASH3,TIFA,TPRA1,B2M,SLC52A3,CASP4,SLC15A2,SPOP,DEFB129,TRIM22,CYB5R4,MRPL36,AMACR,NR0B1,GABRG2,TFIP11,PRKCQ,WASF3,IKZF2,CLEC9A,RPL8,PGM1,HADH,NAT9,CLCA1,TMEM88,CNOT6L,CD1E,GTF2IRD1,TRMT11,MRPL40,SMCHD1,B4GALT7,ZSCAN5A,SOX3,RPS4X,TMOD3,COX19,MAP3K12,ZDHHC15,RSPH1,FBP2,PPIA,LECT2,POGK,SLC16A4,TRIM52,HNRNPA1,ACOT8,NFE2,LRTOMT,NCKIPSD,CTSB,DEFB121,RPS29,ALKBH2,SKA3,CYB5A,TFG,ELOVL3,MTX2,MAEL,CDK8,BSCL2,RNASEK,IQCF5,PHF23,COX10,VAMP3,WDR83,VLDLR,CRB3,DHRS7,IKBKB,HELLS,MITF,LCA5L,HTRA1,KIF3B,HRAS,WDR20,SYT4,RPP14,TAGLN2,RPL13A,FAHD1,TRIM8,GPX2,HCLS1,DNAJC1,TRIM46,EHHADH,GLRB,EMP2,LILRB1,OVGP1,STBD1,FAM110B,TRIM63,PAQR9,THAP2,IL4,TIAM1,FAM50B,STX10,TUBB,LSM14B,ZFP64,COIL,CHID1,DISC1,SSR1,AVPI1,NETO2,SMARCD3,RBFOX3,ZNF596,RING1,MCHR1,SFN,TRAPPC10,SF3A1,GNAI3,PSPC1,INPP5E,ORMDL1,ASB8,CDC16,GNB1,GLTP,PYCARD,CUL2,SLC6A8,MED30,GHR,CXCL11,MED9,SOCS4,TREML1,GSTA4,RHBDD3,PPP5C,RBM42,LDLR,FOXP3,OR7E24,VPS4B,TMEM160,ANAPC11,LACRT,SEPHS1,TOMM7,PCMTD1,RASGEF1C,MAP2K6,MAD2L1,CA10,CD52,CYP3A5,DCUN1D3,LMNA,PHF1,RNF41,ZNF7,DCAKD,PLP1,XPNPEP1,MGAT4B,TMEM74,IRAK1BP1,TIMM8B,KLRD1,FASLG,CTBP1,EIF3E,CDC42EP4,MSRB3,DDT,JUP,ALKBH3,EXT1,EXOSC4,BUB3,SNX5,CFL2,SLMAP,ZMYM2,OR4N5,EIF4E2,IL13,GRM8,UTP15,MCM8,HP1BP3,PACRG,TAS2R16,TLCD2,MT1A,CD38,PNMA2,ANKRD49,CAMK2N2,CUTA,DLAT,RMI1,RIMS3,GRAP,EPYC,SELENOT,PHC1,BLOC1S3,TAAR6,PLXNC1,UGT2A3,PHF12,GEMIN7,ZBTB33,BAG2,DCP2,MED17,NOB1,TMEM184C,SNX2,NOL7,CAMK1,WFDC5,TACO1,NSA2,SSBP3,NXPH3,DEFB115,NOVA1,INPP5K,MCAT,NUDCD3,SEC63,IRF2,TM4SF1,BCCIP,ERP29,PTTG1,DCAF4,ARHGEF6,PCSK2,CYP4F12,CPE,SLC39A13,CDC40,SCN1B,TM2D2,NDUFB5,OR52W1,SUB1,NELL2,REXO2,GPHA2,NTF4,POC1B,LRTM2,CYB5R1,USP2,MYT1L,SFXN1,UBAC2,NME2,CD4,UBXN6,KCNF1,NR4A2,NOSIP,SLC25A45,G0S2,OR5I1,TRA2A,SATB1,BEND6,PRMT5,GANC,ACO1,CACUL1,PPTC7,PCK2,TSHR,SLC25A20,NEUROD6,AIG1,INSM2,EIF2D,DYRK1A,DRP2,RAB31,OR8K1,STC1,KLHL32,SRGN,LIMD2,COPS2,TRIM27,EIF2AK2,C1GALT1C1,LGI3,GTPBP2,NICN1,RAB30,RSAD2,GABRA2,SST,COMMD5,PFDN4,NAA35,GSTM2,UBFD1,PPP4C,NRBF2,PPIG,EFHD2,DNAJB2,PSMA2,GGT7,GRXCR1,DAD1,MFN1,ZBTB2,TAS1R2,CNR1,PLA2G12A,CAMLG,NPY,CPNE1,GNB4,CNTN1,ZER1,ACTB,DDAH2,MATN4,LNX2,TYW3,SNX18,RFC2,CD1A,LPAR1,HSP90AA1,HDDC2,PPIH,FNDC9,DCUN1D5,FOLR2,PDRG1,SOCS3,PTPN22,AP2S1,PGAM1,RNF121,UGDH,RPS13,CCSAP,EPO,ZNF280B,MMP21,EID1,CHCHD3,NFKBIB,TM9SF4,TCEANC2,LRRC1,NUP37,MXI1,USP5,FERD3L,ITGAV,LDHB,RPF1,FOXP4,RNF126,TMEM182,AURKAIP1,AKR7A2,FXR2,DRAM1,IL1RAP,VKORC1L1,SMARCA5,ELK4,FAIM,BAK1,ATP1B1,GPR85,PPP2R3A,SMAD4,SLC22A8,DRD1,SLC1A3,RILPL2,FZR1,SMC4,GTF2E1,TNNC2,OR8I2,AK5,RAB22A,CLVS1,FAU,CYP2F1,PSME1,KBTBD4,PNO1,AGAP1,SLC6A12,TRIM10,UBE2E3,UBE2M,PIR,OR5AP2,ELAVL2,MOSPD1,FCHSD2,ISCU,MORN4,GIMAP4,RPAIN,UNC119B,TBC1D4,PSMC1,MED21,SSRP1,PAIP1,OCIAD2,TWSG1,OR9K2,HPGDS,NDUFS3,RLN2,OSBP,GOLGA5,DNTT,FGF10,TLR2,HECTD1,DYNC1I1,LGR4,ARMC1,GABRB2,TFEB,SYVN1,HSCB,CES5A,CCDC122,PPP1R12A,IL6,GRID1,RERE,KLHL12,SERPINI1,PPM1D,IDO1,SLC25A28,SLC39A3,CXCL12,MSL2,FLCN,RSRC1,RPL35A,ZNF668,CD248,TNFSF13,FLRT3,GRPEL2,STIM1,TMC7,LRIF1,FTL,MYOZ3,EIF4E3,TCAP,RIC3,ARHGAP25,DES,PCDH9,ZRANB2,LIN7B,ZNF575,CCL20,MRPS7,ARHGAP5,VTI1B,GLT8D2,SPATA6,MOG,LRRC57,PLSCR4,SCN3B,OSGEP,NMI,RIMS4,NDUFA2,IFNGR1,NUP50,NSFL1C,TMEM190,OGN,SCPEP1,PADI2,POLR2F,NDUFB10,POMT2,GNG5,TMEM14B,NIF3L1,RRN3,DHPS,UTS2,TLE1,ARL6IP6,HMG20A,BTF3L4,CYP27B1,PNOC,YBEY,NTPCR,IL15,MRPL10,CISD1,MORC4,LANCL1,PIK3R3,MKKS,SLC35B4,TERT,METTL6,RASL10A,TUFM,GNG13,OR51M1,IFNA2,IDH1,KRTAP12-4,VPS28,MPZ,SRC,CD2AP,CHRDL1,NLRP6,TOMM20,TRAF3IP2,PTGER4,BAHD1,DHRS7B,PSMB6,ZCCHC17,IZUMO1,PIP5K1A,IFIT2,RAB33B,SECISBP2L,MCM3,CDC42EP3,RNF115,RASGRP3,ENTPD3,RCE1,MGAT1,RGS19,PSMD12,CKLF,CCT7,SLC25A11,PAFAH1B1,KCTD15,PDCD1,MS4A7,NEUROG2,MTMR6,LUM,SEMA6C,CCDC85B,ICAM3,UNC50,HMX2,CHST11,RPL7,YTHDF1,TUBA1A,CELF6,FCGR2A,NAA50,MED31,SH3BP5L,NFYB,SLC25A17,LRWD1,EEF1G,ARRDC3,ZCCHC12,STXBP6,PDE1A,DAPK1,LILRA1,TPBG,KCNQ5,EDNRA,ST6GALNAC3,TBC1D24,SYT2,SPOPL,LEPROTL1,TMEM95,NR1H2,BMP1,PRPF31,PHB2,TTC1,MMADHC,SESN3,CDSN,ZNF692,SLC25A44,YWHAB,THY1,PSMD14,RNF39,HDAC6,PBLD,TMEM176A,CNTNAP1,ANAPC13,EYA3,DUSP26,TSC22D3,NANP,USP14,TXNL4A,CISH,CXCR6,GNA14,AGPAT1,ZMYM4,EIF2S2,BTG1,CHMP5,ASB3,RERG,POLR3F,RPL35,FRS3,RRAS2,ATL1,TPT1,SNCB,ACTL9,GTF2A2,RNF20,GPR15,PPARA,COPS7A,STOML2,OTUD6A,MICB,TOR1AIP2,NUP153,BVES,RAB14,GOLGA7,TMCC1,REP15,SDC4,WASL,CD79B,ZBED4,OR4N4,DYNLT3,SP4,TMEM31,PTN,SSBP1,F10,KCNA3,NDUFB7,NEK2,NDUFV2,ZNF526,PC,RAB5A,APOBEC3D,DPP4,PRDX2,LMO3,EIF2S1,UGP2,LMBRD2,MRPS33,PAX6,STAT1,ZNF507,CD151,RPN1,KCTD9,TLR6,DLG1,P2RY11,IL3,MSX1,CHRM1,SHMT1,CYTL1,NDUFA4,SLC45A3,HEXB,PPFIBP1,SYNGR4,OAF,MOBP,PKIG,TSG101,MAMDC2,ADCY2,THBS3,CALR,TRUB1,SNAI2,DRG2,CYB5R3,PLAC8,NDC80,SNAPC5,RPP21,RAB13,OR10G2,MAP1LC3A,RNF26,PATE2,CDK5,GNG3,MRPL51,NME4,FNTB,YIPF5,TOB2,SLC6A4,PDSS2,SFTPC,ZC3H15,ODC1,SLC25A23,DSN1,RAP2C,LAMTOR1,ADNP,DDX5,EIF4A3,CYTH1,SLC1A1,PDE9A,CCDC71,CCHCR1,RPS5,SNAPC2,SLC22A12,FOXP2,CYP17A1,UBE2F,UBN1,TPSG1,ALG2,MBLAC2,PHKA1,COG1,RPL10L,SCYL2,MCHR2,KLHL7,ZNF330,OR51A4,DET1,CSTB,GTF3C3,RNF14,PRRG1,SAT2,GPNMB,IRF6,RAF1,RGMA,DNAJC10,MEF2C,DRAP1,LRRC4,LITAF,ARFGAP3,ARL4A,IL1B,GPR26,PLAA,RPRM,BAP1,DOHH,FUT1,LY6G6C,RHCE,ANGPTL2,FKBP10,BAALC,PHAX,RIMKLA,GPX4,EXOC1,FGF12,SEC62,SNRPD3,LAMTOR3,ZNF175,GPSM3,TP53INP2,GOLPH3L,TNNT2,STK11,COMT,TESK2,RPS27L,SEC61A2,ELAVL4,TRMT1L,KCNMB1,GABARAPL1,CD46,GNAI2,CDC123,UCK1,PEX5L,TM9SF1,COMMD2,MAGOHB,FAM118B,CBX5,ARL10,MYCT1,DEDD,BOLA3,CDC42EP2,PPM1G,FLRT2,TMEM209,GFI1,GLYAT,MRPL52,MYD88,FCF1,CD1D,PLN,E2F4,GLRA1,G2E3,RBM18,QPCTL,TOPBP1,MTG1,RPL3,PROM1,VMO1,TRIM11,C1QL3,MRPS18A,LCMT1,YIPF4,CSNK2B,TMUB2,MAX,OR4K17,RHOB,NRSN1,HOXB1,NLRP1,CNPPD1,GZMK,TMEM199,FBP1,RP2,CENPP,STX12,CD1B,GCC1,LRRN1,DNAJC27,KDSR,ZFAND2B,DNAJB6,AOX1,PSMA5,B4GALT1,STARD13,CRKL,ATP1A1,TGIF2LX,NDUFA12,NUDT5,EGFL8,ARL15,ILVBL,AZI2,KATNAL1,TNFRSF14,TXNRD1,TMOD1,GTPBP1,KCNMB2,RPS11,GSTK1,NAE1,COCH,FEM1C,PIK3AP1,LST1,PICALM,COX6C,XAF1,VTA1,RPIA,CRTC2,GSTM4,TMEM38B,TSPAN15,NPM3,NUDT2,GH1,PEBP4,BAX,ATP1A3,PSD2,TMEM185A,NDUFS2,PAIP2,PIK3CA,IVNS1ABP,SNRNP40,FAM83B,JAKMIP2,CDH11,PSMC3,CPT1B,ZBTB39,RBM27,CNN3,ANKMY2,LY96,AP1S2,MAD2L1BP,TMEM47,AKR1B1,APEX2,ADORA3,SF3B1,TAB1,CA2,SNX10,USP6NL,MTDH,SGTA,TPPP3,ZNF263,SSX2IP,BCL6,E4F1,TMED9,GSTCD,GTF2F1,DLST,CBX3,DR1,GTPBP8,HS2ST1,TRPC1,LYPD6,ELMO2,BCL9,ASPA,GABRA1,PRNP,CAND1,HSD17B10,TMEM89,MIS12,XRCC5,ACCS,TIMP4,SNRPG,ZDHHC4,WDR5B,CDC20,SEC13,IL2,NBN,VMAC,TNFAIP8L1,TBC1D25,AIPL1,PEX13,WDR11,NHEJ1,SLC35B3,FHOD3,TYROBP,OLR1,SLC19A3,NDST3,FBXO8,PRL,MPPED2,CDC7,MRPS34,IGSF11,CYP2C9,DUSP21,ATAD1,TRIM45,MGAT4A,RBBP8,SGMS1,KLHL1,FOXA3,SESTD1,CARTPT,ABHD12,BANF1,PARP2,NF2,RPL26L1,PHF13,CGGBP1,TFB1M,SUMO2,LZTFL1,SNRPB2,KLF3,CCR4,CHRAC1,GGH,TNF,IL17F,PPAT,NUDT9,CYGB,UBE2E2,FSTL1,HGS,RHOBTB3,POLR2L,POLDIP3,LRRC40,CRISP1,ELK3,DPH3,CD81,MT1E,COX6B2,TMEM170A,RNF133,TSPAN17,PRKRA,PRKCE,ZNF451,WDSUB1,GNRH1,DBR1,TAS2R13,NT5DC1,MRPS18C,TRIM36,PROK1,JAK2,PAQR3,CREBZF,PLSCR1,PTP4A3,DCAF12L2,COMMD9,CBLN1,STK3,HSPB2,LILRA2,TNKS2,LY6H,TRIM29,OIP5,CORO6,RB1,DPH5,PNMA3,ZBED1,GPR35,DDAH1,HFE,NDUFA1,ALG11,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,LXN,TCEAL8,YIPF3,RPS2,B4GALT4,CAV1,NINJ1,ICOS,BLCAP,ITGB5,RGL2,TRIM34,NDUFC2,CPLX2,PRND,HUWE1,ABHD10,FTSJ1,CNTROB,AKR1C1,MRPS11,CSNK1G3,RAB39B,CYP3A43,SPEM1,PDE4B,TTPAL,PMAIP1,CCIN,UBE2L3,EIF3G,MEPCE,AASDHPPT,RNF222,REEP4,TM4SF20,CCNA2,GJA1,MAGED2,SURF2,SLC29A1,TM4SF18,OR6X1,TNR,BOK,LSM14A,CAPN2,OR8H3,SLC8A1,ICAM2,ABHD8,YWHAZ,STARD3NL,SLC25A1,HNRNPF,STAMBP,CEND1,EHD4,ZNF511,FAM81A,GRM1,PCGF6,OR4K2,KCNJ10,SHPRH,SPATA2,SLCO3A1,ADORA1,TAF1D,HOMER3,CXCR3,MAGEB10,PSMB7,TNFAIP6,FBXW7,DMTF1,PLG,DLK2,CDK12,ARL4D,LIAS,CITED1,TXNDC17,TNNI3K,CPLX3,NPY1R,PSMD10,GCLC,EPHA4,CTU1,KCNJ2,ZNHIT6,PLCB1,GPR17,GPC1,PRSS23,FRZB,SPP1,TSR2,CHRM3,ARL2BP,ING2,ARFGEF1,NOG,TLR8,PMPCA,SLC6A2,TNFSF15,CD40,AIP,CRY1,SIN3A,CDK7,PLAC1,SCAND1,PSMD7,RAB6A,CTTNBP2,FKBPL,RGN,PYCR2,PDE2A,ZNF428,CDIPT,TNFSF8,THAP1,UNC79,CD34,FBXL4,CPXM1,PRCP,EID2B,DCTPP1,TMEM100,OR4A47,YPEL4,LDB2,RNASE9,GADD45G,RPA2,TMEM107,PIWIL1,TRAF3IP3,CCDC90B,TAB2,SRPK2,IL2RB,PTGFR,IP6K1,P2RY4,FBXW4,TAS2R7,ST3GAL2,CD209,STAR,RPL10,TRIP4,PDCL,SUPT5H,SLC25A24,GLCE,GK5,SSNA1,RNF10,GP9,OR51E2,POLE3,KRTAP8-1,APLNR,CYP4V2,NCAPG2,SRI,CNPY3,DTWD2,PSMD3,POLR1D,GPR160,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,OR4D5,TEX261,NR1I3,PAIP2B,LRP10,TRIM44,TMEM229B,HINFP,NUFIP2,GNB3,CCDC3,VAV2,BTG2,ITGB8,HSPA5,GNA11,SERTAD2,HSPB6,MPV17L2,CRYBA1,THAP8,WDR45,NRM,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,SLC22A6,SPG21,TIA1,DDR1,SAP18,EXOC3,TMEM81,CAP2,PIAS1,PNPLA4,NPC2,TMEM115,PARD6A,LRRC28,TCEA2,EIF1AX,HSPD1,RNASEH2C,OR1M1,RUSC2,CD9,GRPR,IGFBP3,GADD45A,DPEP3,TMEM183A,BTG3,THOC3,PIGA,GLOD4,MX1,BOLL,RBMS2,TGFB2,VPS54,SLC25A27,ATG9A,ZNF622,S100A11,ANXA4,IL18BP,RASL12,GALNT2,RRAGB,SNRPE,GRIK1,DLGAP4,CMA1,IGF1,CCR7,SNAP25,RXRG,GORASP2,THUMPD1,TTC9C,GMPS,PELO,BRAP,TANK,SYNGR3,MPG,CDC23,MBD3,DMPK,OR5M9,HAUS2,GALC,ELFN2,RP9,LRRC8A,GNGT2,CNPY1,SSPN,LBX1,NKAP,RDH11,PIH1D1,KCTD3,SLU7,VEZT,FAM3C,PTP4A2,MFAP3L,IRF7,TMEM165,OR8B4,KLHL25,RPE,SULT1B1,CYBRD1,ZNF518B,ADCK1,MACROD1,FAM151B,FAM136A,SLC35E4,PRR13,SLC25A5,OAZ1,WSB1,LYZ,TOPORS,FXN,SUPT3H,UPRT,SGIP1,MRPS17,MECR,MRPL9,UBE2G2,FEM1B,NUCKS1,TRIM26,IER3,CENPL,KLRC2,TOX4,IFT172,TMBIM1,CYTH4,CPNE2,RAMP3,SPRY1,RPS10,CLDND1,CCDC106,ETNK2,GIN1,TKTL1,RPL18,TBCCD1,TRAF6,VPS72,KRIT1,ROCK2,KCND3,FUBP3,TRAPPC6A,MDC1,MTCH2,ITM2B,CCSER2,SP1,MGMT,TRAM1,TADA3,FUNDC1,AP1M1,ECHDC1,UBA52,IMPA2,YTHDF2,FAM161A,ANKRD6,SRFBP1,ARHGAP12,EIF5B,PFKFB2,MREG,ACER3,DIRAS2,RASSF8,KCTD17,CLEC6A,SSBP4,RBP2,TLCD1,AQP11,LMO2,FKBP1B,EDA2R,LCORL,OR13A1,PSEN1,MAGEC2,CIAO1,ATP8A1,KIF3C,GHRL,VPS18,ZNF581,DUSP3,PDE7A,SUCLG2,SCML1,ZFAND6,TAPT1,MED10,TYMS,NAA16,GJC1,SLC12A2,RPS20,RUNX1,TLR5,LCN1,RFC4,HS3ST3A1,TICAM1,GPM6A,PNPO,OR2D3,COTL1,SOX9,KCNG3,CHST10,JMJD8,GAB1,ITPRIPL2,AKT2,PRSS1,APEX1,PSMC5,ECD,CD59,ETFA,PRELID1,AQP3,ALG5,DEXI,SUGP1,STARD5,FMO1,ABCC2,ACTR1B,STAP1,HTR2A,SMARCB1,GTF3C4,MMP20,C1QL2,PLCXD3,REG1A,DNM2,OR4K13,TSPYL4,CLRN2,SRD5A3,DCAF16,ADD2,SOD2,TCTA,PCP2,TEF,ANKRD10,SCN2B,VSTM2L,FBXO31,MAP1B,CNOT8,PIGK,PELI1,NEU1,AMELX,VSTM4,PDCD1LG2,GLO1,RAB1A,WDR12,MLN,KLF12,ARHGAP15,RHOH,ERLIN2,UBE2S,HYAL2,NPBWR1,RPSA,PIK3CG,MAGEA4,STT3A,CCDC126,RRP7A,RBM3,RACGAP1,CORO1C,CHTOP,SYPL1,ZNF343,EGR1,ZNF436,WBP11,STARD7,ACTL6A,ACP2,FOSL2,GNPAT,SETD3,GPR75,TMEM126A,NACC2,CHRM5,DRD3,EMILIN3,NAP1L3,CEACAM5,DIS3L,CA14,CEP57L1,OSBPL8,TACR1,ARHGAP19,THG1L,PDLIM4,GABBR1,ERCC3,TIMM13,RPF2,XBP1,TBC1D1,GPR34,MRGPRX1,LIPT2,HPCAL1,TRMT5,OR9I1,BCKDK,ZCRB1,MED4,APOC2,CYB5B,NAP1L5,SEMA7A,BIRC5,MFSD3,LDB1,TRAPPC3,NRGN,CSRNP3,GMDS,WNT2,SAP30BP,HAPLN2,EDC3,AANAT,ANKH,YKT6,VPS26B,CAMKV,ESYT1,F2,ARL5B,CYP26A1,GMNN,RALB,TMEM87A,NUDT1,ISG20,FKBP2,PRSS35,UNC45A,TBCEL,CCDC22,KDM1A,NDFIP1,DTL,PSMG2,ARL6IP5,CEP70,ABHD2,CTDSPL2,SNN,SNRPA1,POPDC3,RETSAT,SLC7A11,MET,FZD6,ADIPOR1,GAL3ST4,PRM1,GFM1,SSH3,HOXB8,EMX2,SEC61G,CENPM,PDE6A,IMP4,HELT,TRNP1,TIMMDC1,SERPINB9,UBE2V1,MT1X,RPLP1,SNX11,TMEM176B,CEBPE,RPL22,DLG3,B3GALT4,RHOU,ACSS2,DEFB1,IFRD1,MAP1LC3B,PDLIM3,PRSS37,ATF3,CTLA4,RBM5,RANBP1,TEX19,TRIM62,ZNF655,HNRNPAB,GPR78,PLEKHF1,ZBTB6,AHSA1,SLC15A1,KCTD16,SIAH1,STRADB,LRP3,NCK1,ST8SIA4,TMEM220,TMEM168,CD200,OR6C4,RFX5,TRAPPC2L,NMRAL1,MAT2A,SCG5,PHOSPHO2,TAF9,MEA1,HMGN4,SCHIP1,COX7B2,CMBL,CDKN1B,UQCRC1,NOC4L,CRHR1,AKR1E2,HAS3,PRPS1,OLA1,TSPAN3,BAD,MGST3,RPL31,WTAP,GDAP1L1,SSBP2,PDCD10,LRRN4CL,PSMB4,HERC3,DOK6,SEMA3C,LSM4,IRF9,HSD17B8,DDX39B,CGRRF1,NETO1,CDR2,PTGER2,C9orf72,NAA30,ZMAT3,BRS3,TRAF1,RSL24D1,CLK1,SKAP2,SERPINA3,KCTD20,RASSF4,ARF1,ZMYM6,EIF2B2,GNG11,PHF7,MRPS26,HMGB1,CKB,TUBA1B,THAP6,LRRC14,ZBTB26,EMILIN1,PDCD5,PRDX3,BTBD10,LPCAT3,GPR83,ZCCHC7,PHTF2,PPIL3,CTSA,DPAGT1,HNMT,FA2H,ERRFI1,KCNIP2,SERTAD1,ZHX1,ZNF770,TPD52L1,DUSP18,RPS28,SMUG1,SVIP,CDH7,ASCC1,SLC37A4,CXCL10,FBLN5,LYRM2,FOXD3,MAEA,KIAA1958,EID2,ZNF345,RGS1,SDHC,ASB11,FAM83A,RHOG,NOL12,COX7B,CDC42SE1,BGLAP,GAD2,METTL18,RSBN1L,SEC61A1,TTR,UBE2I,TMEM106B,UCP2,MED29,MXD1,MFAP1,LAMTOR2,SLC41A1,PNRC1,EZH1,ARGLU1,RNF7,TECR,MRPL16,KRTAP4-1,MAP3K3,ARL11,FHIT,IL21,RPL19,HBM,POU5F1,MSN,FGF16,ZNF362,SLITRK5,SAP30,DDIT4L,RNASE4,DICER1,SLC6A7,MAGEB1,SNRNP70,SERINC1,PLEKHF2,GLIPR2,TDP1,SPCS1,MID1IP1,RIT2,IFNA13,CACNG3,ZC3H14,CBFB,ASPM,EFNA5,ZC4H2,CETN2,TADA1,PITHD1,SMARCE1,SH3BP4,LEP,UBE3A,OR4B1,OR5K1,PDZK1IP1,PDE6D,TNIK,S100B,LRFN3,ZDHHC24,B3GALT2,PPT1,ARF6,MRPL12,FGR,RCHY1,SPHK2,CXXC1,RPL7A,FIG4,LSM12,DOK5,DCTN4,MAP2K3,SEC22A,RPL28,CACNB2,HCFC1R1,EDEM2,FIS1,SRP72,SLITRK1,DDIT3,PREP,CDC26,SHC3,PIGC,ARFGAP1,MVD,STK38L,CYP4F22,PTPN5,RNF182,TIMM17A,RELL1,SMAD9,LIPA,CCL24,SNRPD1,JUNB,ALCAM,WBP1L,VCPIP1,SLC39A10,MCCD1,TCEA1,HM13,BCAS4,PGAP3,MB21D2,LCN15,CCL11,RAB9A,RXFP2,RPAP3,HINT1,TNPO2,PYCR1,THOC6,SLA2,IFNAR1,SDR16C5,MARCKSL1,RAB11B,ARL6,STX5,CCND3,CSRP1,IRF4,LEMD3,SPATA4,CMTM7,TBC1D16,SLC7A1,CA12,ADRB3,FMOD,NUP62,SMG5,RNF139,PLP2,ABCF1,DUS4L,DYNLL1,LYPLAL1,HSDL2,OPRL1,PSMD1,BARX2,MPP1,MED27,SRM,RANBP10,ADH1B,BMPR1B,OR4M1,HS3ST1,TULP3,PCBP4,MLH3,APOBEC3B,BLVRA,RAB32,PITPNA,CRYBA4,CRYZ,FOXC2,PSMB10,CDK17,ART5,TMEM39A,CDKN2D,GPR37,ESD,ATP6V1D,VWF,CLP1,CLPX,OR5AN1,CFTR,ATG3,INA,VPS39,MYLIP,FAM174A,SUPT4H1,SART3,PTPRZ1,IFI16,ZNF200,IZUMO2,TPST1,LCP1,AGGF1,HNRNPH3,GJB1,GCHFR,PCYT1B,CSF2,KRT8,PRELP,CHCHD2,SKP1,TTLL10,SIGLEC5,HDAC11,ATG16L1,DIRAS3,TP53TG5,DYNLRB2,CKS1B,SPAG11B,HBP1,RPL4,RGL1,SUV39H1,DCTN3,LSM5,IRF2BPL,PRKCB,PABPC5,HCFC2,SLC25A3,RWDD1,COPE,RBM41,FUT8,WBP2,GTF2A1,UTS2R,NEK7,LASP1,PHKG1,SPOCK1,MOB3C,CXXC5,ENDOD1,CIRBP,ANKIB1,EIF2B5,SH3GLB2,GALE,IL23A,PSMD6,FURIN,SLC39A9,DHX9,ZSCAN1,OR51S1,EIF4EBP3,WDR37,CREBL2,TXNIP,AQP4,CCL25,GNMT,DNAL4,FATE1,ATP2C1,RC3H2,NUDT19,RANGRF,ABCC5,THOC1,GSK3A,PRCC,LDHA,PFDN6,NUBP2,UBXN10,PCDHA5,SLC20A2,ZMYND11,SLC7A4,ZNF513,GPR162,APOBEC3C,RNF187,XPO5,INTS10,SURF4,TF,RNF103,CREB3,EEF2,THRAP3,GJA10,SLC25A32,EFHC1,XPO1,EXOC2,RBM23,TMED1,OCEL1,ADAT1,HEXA,BRI3,OXNAD1,IPP,NQO1,TBCE,SPATA2L,NPVF,LMBR1L,AKR1C2,IGFBP4,OPA3,TAC1,KIF1C,CHRNA7,GAS8,CDKL2,CD3G,PAOX,BRMS1,ACAA2,UCKL1,RAP1A,RABAC1,WWP2,TIGD7,FBXO30,CD2,POLR2I,ST13,LPXN,RASGRP2,IL34,DFFA,KCND2,CCL21,NDUFA5,TRMT6,PTCRA,NEDD8,CXCR1,HBB,FGF17,SNAI3,PELI3,CDC37L1,KRR1,NLE1,RPRML,MSX2,WNT7A,LEPR,STX17,EIF1AD,NAA11,ISYNA1,NDUFB8,APH1A,CXCL1,PDIA3,FRA10AC1,XPOT,OR6M1,NUDT16,GXYLT1,B4GALT6,KCNA2,HSPB1,LHFPL1,HADHA,LEAP2,DHX16,RAB4A,SOX21,TRA2B,SERPINH1,RPL37A,HSPE1,CLDN14,ZKSCAN1,STAMBPL1,SIPA1L1,PGBD2,ZNF174,USP38,SLPI,USP39,CERK,ENPEP,NAB1,SYNGR1,RTP4,LSM6,PRKX,FGF13,PROX1,RAB8B,CTNNB1,CYP2D6,SOCS2,INTS12,SFTPD,CLEC12B,SNRPD2,ADCY3,DCAF5,ESR2,CWF19L1,CDK6,TAPBPL,ETV6,RRAGA,SIRT7,FYTTD1,IQSEC1,NOL4,MMACHC,TRAF7,MTMR12,DUOXA2,RAP2B,ABHD16B,TNFAIP3,GFOD1,SIVA1,SNTA1,SNAPC1,NDUFAF2,GPR37L1,TCP11L1,SOST,SV2B,HPCA,ZNF805,OR2A2,EIF4EBP2,TSSC4,MAK16,ALDH1L1,POLL,NONO,SPRED1,H19,DEGS1,CRYBA2,CCDC42,FCAR,NPTN,POU1F1,CYC1,PTDSS1,ID1,ENTPD4,SLC35A2,ARMC8,KIF2A,BACH1,MIA2,INPPL1,CTSD,PGAP2,MRGPRX4,FABP5,AKR1A1,NOP58,SPATS2L,NFE2L1,RBCK1,MRPS25,PPIB,BPGM,CDKN3,CD164,NUP107,OR52M1,SCAMP2,SPEF1,SLC5A6,CYP4F8,PRKD3,NLGN2,DEK,DCAF8L2,AP1G2,NDNF,ANP32B,CHST9,CPT2,NFYA,S100A10,FAM200A,STX8,DUSP1,TGFB1I1,TOLLIP,BATF,PWP2,RAB3C,MTAP,CTSK,CACYBP,CETN3,URM1,FAF2,BMPR1A,SPINK13,RHCG,SCG2,ARHGAP21,AP3S2,MRPL47,TMEM33,S100PBP,MPHOSPH10,KLF10,RPGRIP1L,OR2W1,CCND1,WFDC13,ACOT13,TMED3,FBXO9,COX7A1,LCN6,SETD4,UGCG,MEAF6,LYPLA1,RPS14,LIG3,SLC17A5,ZNF671,SLC25A31,POLR3H,TRIM3,C1QC,TMUB1,ATP6V0B,TMEM219,EDF1,ZNF207,MRPL23,GDI2,GFM2,E2F6,ZMPSTE24,EXOSC1,EFCAB7,GPR89A,UBR7,PDIA6,SDR42E1,CD99L2,PRIM2,SNRNP27,TRIM32,KLHDC8B,RNF141,DOK4,ARHGAP1,PLA2G5,KLK9,RND3,CNP,NUDT3,B9D1,LYAR,GNRHR2,TOM1L2,PFDN5,EXOC8,UST,MRPL13,EHBP1,MDM2,MGP,SPRN,TMEM156,GSTO1,GALNT1,AK2,SOCS5,PSMA3,CCDC69,FNDC8,COMTD1,APEH,FGD2,DLX1,AKT1,L1CAM,FIBIN,SNX20,TLR9,CCNI,ASMT,RAB11A,PPIL4,CDO1,CRABP2,PRRC2A,DPP10,RPS23,SF3B4,DKK3,IL20RB,CHDH,GNRH2,CYP39A1,HSD11B1,MYL12A,LRRC69,SWAP70,FAM8A1,EIF4H,ITK,NCR3,TLR3,GPAA1,JAKMIP1,ADGB,SENP5,IDH3B,CYP11B1,PYDC2,CTNNBL1,GRM2,RMND1,MIOS,FAM78A,PPP1R2,IL15RA,OSM,SLC38A9,MRPL50,MRPL24,ZNF304,SNAPIN,SLC30A5,KLK3,ENY2,RAG1,IMMP2L,DHRS4,SLC35A1,FGFR1OP2,GABARAP,PRPSAP1,ELMO1,GRPEL1,TCP11L2,LTBR,OR4D11,GAL3ST1,CASK,IRF1,OR8B8,STRBP,P2RY1,ING1,NAIF1,TRIM23,NHP2,CCT2,ATP6V0E1,UBE2D3,UBE2A,ARMCX1,ID4,ZNF319,SEC14L1,APOBEC3A,ZNF397,XAGE5,SLAMF9,ZMYND19,TAAR1,CCR6,ATPAF2,KIAA0232,CLU,LMO4,GLUL,CNIH4,CDK5R1,NCKAP1,NRP1,RS1,KIT,LSM3,OR4D9,AFTPH,JOSD1,P4HA2,SUPT7L,KBTBD2,GSTO2,ATF4,GNG7,CTNNBIP1,RARRES2,GRSF1,KPNA1,PIWIL4,CSNK2A1,TMIGD1,DNAJC5,SNAP91,MYH2,ALKBH4,HEBP1,SLC7A9,PACSIN3,PGK1,VRK1,ROPN1B,MMP9,BTF3,S100A6,DYNC1I2,CYP27A1,ZYX,UBAP1,CDC73,LHX2,TSEN54,SERPINB10,FBXO42,TMEM215,ZNF24,LYG2,MFSD6L,GPBP1L1,MX2,SYN3,ZCCHC10,AAMP,FZD4,MEST,MTPN,WDR77,ATP6V1G1,RAB3B,CDCA3,SMAP2,KTI12,NDST1,TNFAIP8L2,DEFB116,DHRS3,NKX3-2,TBC1D10C,CCL19,MAGOH,MLF1,GTF2E2,LBH,JAK1,FGF1,ABCB1,HBE1,INO80C,AZGP1,PSME2,AZIN1,SPR,GALNT12,ARFIP1,PPARG,ACTA2,SIX5,TRIM21,ARMCX2,RMND5B,RBBP7,SLC25A21,PGS1,NFIL3,ZBTB38,TRIM37,HECW1,PTPN1,HNRNPC,SETD5,SLC35E3,SPTAN1,RNASET2,NPY2R,LRP12,FAM199X,PAEP,NIPA2,RABL2B,CLDN11,TRAPPC1,HEY2,PCDHB8,RBM17,ZDHHC14,ADRB1,PKNOX1,FRMD8,RFX4,CCDC127,RCVRN,PEX3,FAM89B,PPP3CA,KCNJ11,CRYGB,CD200R1,CAMK2N1,HCRT,FGFR1,SHC1,PYGM,OR4K1,CCDC47,TTC4,SCFD1,GHITM,TUBG1,RPL15,CIB3,TACR3,PRMT2,CAMK2G,BUD31,SRP54,TMX4,IMPACT,CD58,AGER,FKBP14,IDH2,RAB18,ARMCX5,ZNF593,PRPF4,AGK,ANAPC2,FBXO32,ENPP4,CCT5,MCOLN1,PSMB5,SORD,SBK2,SLC39A7,BRCA1,ABHD4,PCDHB1,RBM7,TRAF2,KCNK13,CDK4,NPR2,CNNM4,NR1I2,DPY30,RGS2,STMN2,NME1,DUSP19,PDHA1,ADPRH,MBD5,NOS1AP,BCL10,KCNMA1,DNAJC3,RNASEH1,TMED7,KLK6,FKTN,SERINC3,SLC41A3,TSN,STOML3,STAU1,PRKAB1,UQCRH,DPEP1,CD36,IRF3,MTHFD2L,KLC2,PAX9,STXBP1,PCMTD2,STOX2,CSNK1A1L,SOX2,ST3GAL1,DERL1,IL18,ZNF501,CEP97,IFRD2,ST3GAL5,POR,SLC32A1,PARP11,LRP6,MRPS21,PYROXD2,STK24,LCA5,RAC2,TMSB4X,EIF4E,TRIM5,CALHM3,LHFPL4,COX4I2,CDKN2C,SNAPC3,BLOC1S2,SNCG,IGBP1,AKAP12,SSU72,DDX39A,RAB40AL,ZBTB17,BCAP29,FABP7,CD274,B3GALNT1,CREB3L4,EIF3K,SPECC1L,KHDC1,NAT2,RINT1,BZW2,OR10G9,TSPAN5,RPLP0,UBE2V2,IL10,FUT9,PHYH,NTN4,RTKN,ITGA6,CSNK1A1,COMMD8,TFE3,IFNA10,DEFB114,MT1M,RNF113A,EFNB1,SH3GLB1,PREPL,THTPA,OLFML3,TSPO2,GOLGA7B,VMP1,SLC19A2,CBR4,HSPA8,EMP3,OSTM1,CHMP2A,CCDC25,TES,LMNB1,BECN1,GMPPB,ADO,CALHM2,YAF2,ELP3,TRIM24,MRFAP1L1,TGFB3,ACSL4,CIB2,MTRF1,ZNF592,EED,MRPS16,ABHD14B,PROS1,GPX3,TMEM204,B9D2,EWSR1,MYO6,NDUFS8,CYP2C18,ZNF740,F9,PGPEP1,NKX3-1,GCNT3,OPRK1,TMEM144,TOP1,SRRM5,NRSN2,GPR137,SNX17,BCS1L,APOO,CHGA,GBE1,PAPSS2,TCF23,HTR5A,TMX3,DNAJC22,EIF2B3,TOM1,BCL7B,GPR65,SEC61B,HSP90AB1,POLE4,GPHN,ISG20L2,RER1,FCN2,RGS7BP,CDKN2AIP,SFRP4,ATG4A,SYP,ZNF862,CSRNP1,MRPS23,FUNDC2,TMEM123,DSTYK,ZC3H7A,AIF1L,CCR2,ZBTB5,IPO8,TMSB10,CIDEB,ARMC7,ATAT1,MBL2,MAP3K11,GTF2H2,PTS,TOR2A,JPH4,AMIGO1,GNG2,EDEM1,METTL14,VAMP5,CSGALNACT1,R3HCC1,SAT1,COL1A2,RMI2,SMU1,SLC35D1,CTDSP1,CCNB1,FAM162A,CRYBB2,AKAP14,NDUFAF4,TFCP2,CLDN1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1K,LLPH,GSTP1,CCL2,TMEM45A,RNASE1,CGB8,NLRP9,FAM43A,LAMP2,TMEM237,PEA15,RNF8,EP300,ADAMTS10,MRPL20,STAT5A,COPS5,OTX2,EIF4A2,MAGEH1,PRDM4,FEZ1,FPGT,LRRC3B,PLCB2,MAP2K1,APOBEC3F,HSD17B6,TMEM167B,CNOT2,OTOS,CRHBP,ZNF326,PLEKHO1,MYBL2,GSTM5,ERAS,FCGR1A,DNAJC19,VGLL4,SCML2,CLDN12,GPR176,PKP4,ELF5,CHKB,CCNY,CLEC2B,CBR3,SEPHS2,JKAMP,ADD1,LANCL2,APOBEC3H,GLRX2,ASB7,PRKACB,VDAC1,FEN1,CLPB,KLF1,ODAM,CEP19,CHMP4C,PDAP1,SOX14,SLCO2B1,CX3CR1,IGF1R,UBP1,MAVS,KLHL22,DROSHA,NR2E1,ORC6,FLOT1,THOC2,STARD4,FAM177A1,DCTD,SCNM1,MCM4,POLR1B,CER1,SIAH2,CHCHD6,UPK1A,HOXC4,RFXAP,EPS8,MTM1,BIRC2,FCGR2B,NUDT7,IFIH1,UMPS,CD1C,SS18,MRPL22,CDCA7L,PHACTR1,SAMHD1,CRYM,TPH2,SPRYD4,KCNS1,FKBP1A,SRXN1,P2RY12,DNAJC30,EHD3,ST3GAL4,MRPS18B,ZMAT2,NT5C2,DOLK,RPL9,TST,RNF5,DGCR8,API5,EXTL2,RCCD1,SLC20A1,ALPL,ADIPOR2,LAP3,C2CD2,EFHD1,SAMM50,KCNJ8,ENC1,PYGB,TRIM6,HOMER1,PSMB9,PDE8A,SLC4A10,FOXP1,ADM2,IZUMO4,ALDH1A3,AHCYL1,NPTX1,CLIC4,COX11,HNRNPH2,HMOX2,KLHL26,BET1L,WRAP53,MAP3K21,MMD,GAS2,UCHL3,TRAPPC4,EEF1A1,PAAF1,TFPI,PRKCA,BRD3,SURF6,FAR2,TMEM108,DVL2,TESK1,TTC33,C2CD4C,OR2AT4,RPL39,ANAPC4,ARPP19,GDPD3,LRRC4B,TOMM40,GREM1,FABP4,COX4I1,MPHOSPH6,MAP1S,BHLHE40,PI16,MRPL53,HDAC3,RPL29,GLRA2,TXNRD2,DNAJB4,C2CD2L,RAP1B,AKAP17A,RAD21,AIFM1,SNX14,POLR2G,COQ10B,ACTR1A,LAT2,FITM1,CARHSP1,KLHL9,NPC1L1,TIMM8A,SDC2,ACVR1B,FAH,CAMSAP2,CTDSP2,RPL10A,OR5A2,PLSCR3,ARMCX3,CUL3,COX16,FAS,ATF1,ABCB9,MAD2L2,UBTD1,TMPO,POLR3GL,COX6A2,RBBP4,ELOVL4,PAK6,CHMP2B,CSNK1E,SKA1,GRB10,ERVFRD-1,AKT3,POLD4,MAN1A2,CCDC92,RBP5,EIF3D,DNAJC4,GOSR2,SLCO1B3,FGF23,CYP2R1,SLC25A39,CD14,PRR5L,RANBP6,G6PC3,ZC3H11A,CCL27,TMX2,HTR1A,SFRP1,WSCD1,ELF1,CD86,PNMA5,MANBAL,SLC2A8,PSENEN,OXCT1,ENO2,ZNF704,KBTBD6,FARSA,UBE2H,KLHL3,CFL1,BRIX1,IRGQ,RPS26,RNF40,DDX1,KDELR2,DAP,DPM2,RNASE6,TP53I3,LAMP3,CHPF,MATR3,REEP6,CNOT6,CRADD,PPP1R3C,KCNAB1,AGTRAP,SEMA5A,MCMBP,APBB3,S1PR4,TNFAIP1,TMEM11,RNF11,CYTH2,SYNGR2,APOC4,TAF7,OR4S2,WDR82,TLR10,ZBTB25,CD28,NAB2,FXYD6,GNL1,ZNF473,KIAA1143,SELL,ATP1B3,DNAJC2,GNB1L,PPY,CRYAB,ROMO1,ACO2,VPS16,CLN8,SYK,SLC25A26,TNFAIP8L3,CDC42,SLC48A1,BACE1,DUSP10,SLC38A1,PIWIL3,IL2RG,FTH1,SNX1,PSEN2,SLC35F1,ALB,CCM2,AKAP1,CLEC1A,DNAJC24,PARM1,PSMA6,PCSK9,KBTBD3,AGR2,CACNB3,PCBD1,TTC23,NLGN1,TMEM174,MORF4L1,CPSF4,LCN8,AGA,CD63,GEMIN8,RPS9,MYL6,TIRAP,SEC23A,TUSC2,OR5V1,PSMG3,GPR173,TOP2B,CALML5,VAPB,PNMA1,SP2,HEBP2,SLC6A3,CASC3,CNKSR3,TCF21,VPS26A,CMTM6,EEF1E1,TMEM50A,SMG8,LILRB4,MYC,CD40LG,FEM1A,SHISA2,KCTD10,RAB35,MAB21L1,PPP1R8,CCL28,MKLN1,RPS12,CYB5D2,TXN,MAF1,DUSP6,MTHFS,PPIF,SETD7,ZBED3,DAG1,GABARAPL2,PML,DNASE1L1,PSMA4,OR10A7,SERTAD3,MT3,EIF1B,GABPB1,ARF4,TAX1BP3,ZNF790,RDH12,CALY,TNFSF12,TP53,NFKBIL1,CRELD1,INMT,PRDX6,TAX1BP1,AP2M1,KIN,SENP8,STX7,MGST2,GADD45B,HBA1,OSGIN2,LIMS2,MZT2B,NECAP1,GPC4,PKIA,TRAFD1,TRIM35,PPM1B,GSTM3,SYNDIG1,TSEN34,FTSJ3,SLC25A46,HEXIM2,TBC1D17,TMED4,HSD17B1,TOX,PTRHD1,IRF8,KPNA6,RWDD4,CYB561,BET1,FCER1G,OR5B3,BRMS1L,HCST,FBXO34,PAPOLA,DHRS1,CHORDC1,ZBTB16,ANAPC16,TLR1,CAPG,OGDHL,CCR5,SAR1B,IL12A,RHAG,PPP2R5A,VASH1,TLR7,GAPT,PTGES,ACADS,RNF128,SYBU,EXOC5,SERPINB6,NAA15,EBLN2,WDR55,RALA,FTHL17,F11R,G6PD,ADK,ALOX5AP,ELOVL6,TFPT,NUP35,ZNHIT1,MECP2,PRDX4,SLC25A14,RASL11A,CLSTN3,TBC1D19,RGS6,CSTA,OLFM2,ENO1,GNPTG,CHST7,SERPIND1,ORAI2,CRYL1,RPL24,OMG,GPD2,CELA3B,FBXL7,LBR,CYP11B2,PHF21A,COX5A,THNSL1,SLC1A2,TRMT61A,RHBDL3,CAMP,DCAF4L2,RPRD1B,SNRPN,TSPO,LYPLA2,POP7,STYK1,RNF181,YIF1A,OR10Q1,CA8,NMBR,LGALS3,MAP4,LUC7L3,HHIP,RAB3A,DDIT4,SMYD3,KPNA2,FAM91A1,LCN12,CTNND1,FOXJ3,ORMDL3,RAD23B,USP30,UFM1,HAX1,LRRC20,EGR2,OR1F1,RPS3,CHN2,TMEM60,HBEGF,CALU,AIF1,MYL12B,GINS3,ENHO,ATP6V1E2,ZHX3,IL7,SRSF4,NECAP2,SH3BGRL,EXOSC3,PID1,KCTD11,OPTN,GPR146,CLEC7A,APPBP2,ARPC2,POLR2D,SNX12,CNTFR,KRT222,PDP2,SMNDC1,NEURL2,NDP,TMEM42,SNX33,MED23,USP13,SDCBP,FGF3,DRG1,ERLEC1,CEP85,SRPRB,LRRC8D,VIP,ETFB,NTNG2,FBXO11,RBBP9,SPSB1,WNT10B,DGCR6L,AP2A1,APTX,HRH2,SPINT2,ZNF688,BCL2A1,TMEM45B,ZNF22,TFDP2,C1D,ACTR3B,MIF,RBM15B,ZNF189,EEF1B2,PABPC1L,LSM2,TMBIM6,CCT8,DNAJC7,CD83,RPL12,KCTD12,UQCRQ,SOD3,DUSP22,GFOD2,ADAMTS20,YWHAH,FAM187B,GABRB3,MRPL49,PLCL1,MTMR2,ICAM1,AUH,TFRC,TTC8,ZNF267,IDE,ZNF177,ZNF652,HSD17B11,PPME1,C1QTNF1,HMGA1,OR1S1,SH2D5,FOXI3,UTP6,MND1,TSPAN11,GGPS1,IPCEF1 |
| 2.713e-16 | -35.84 | cellular response to organic substance | biological process | GO:0071310 | 1716 | 655 | 18204 | 5365 |
EDNRA,WNT10B,SERPINB9,IFI27,SIN3A,PAX6,ADCY3,RIGI,ELK1,SMYD3,LDOC1,CIB2,CD36,CDC42EP4,CD80,OPTN,JAK1,MYBL2,SYNCRIP,ILDR1,GNRHR2,RWDD1,TNFRSF1B,TLR9,PCK2,IFNK,PLCB1,CXCL3,FABP4,CDC73,MIR96,IFNA2,MIR21,MSX2,SELENON,LILRA2,AQP4,FCER1G,UBE3A,IL12B,RNF14,UBE2K,MIR185,MIR223,YWHAG,CXCL9,SLC2A8,FOXP1,ADIPOR2,PADI2,GNAO1,GNAQ,IFNA10,PTP4A3,MMP9,BGLAP,CD86,MIR107,AHCYL1,CSK,IL6,TRAF3IP2,BAX,EIF4E,TP53INP1,ERRFI1,CD274,CA2,LDLR,HSPD1,MX1,PRL,VPS26B,AKT2,SLC1A3,DAPK3,VEGFC,FLOT1,RXRG,IFNGR1,PPARA,HAX1,MT1X,OXSR1,LRP6,PCSK9,MIR187,STAT1,NR1H2,PHC1,STXBP1,JAK2,BCL2L1,ACACA,UGCG,BAD,DERL1,KRT8,GSK3A,ADCY2,PRKCE,EGLN2,CDK5RAP3,RAMP3,PID1,KIT,CD14,FAS,EIF2AK2,EIF4A2,TOLLIP,GRIA1,MIR320A,CDC42EP2,XBP1,RPL13A,CREBZF,CRKL,MSN,NCOA5,TRIM24,AR,SLC8A1,IL2,PLAA,PAK2,CCND1,NSG1,CALR,PIK3R3,UCP2,UBE2W,PDCD10,EP300,IGF1,NFKBIA,GPX1,OXTR,GPT,CCL24,MT3,CXCL11,GSTP1,SLC1A2,HYAL2,CTSK,BAK1,AGTRAP,VDR,NPR2,MAP1B,SLC1A1,TNFAIP3,GH1,CTNNB1,IL1B,TBC1D4,AKT1,AIFM1,PPP3CA,UBE2G2,FAM107A,MIR182,P2RY4,CEBPE,SMAD4,GRB10,TANK,SELENOS,DRD3,ITGA2,TLR6,IFNA13,ALPL,MECP2,FGF23,MIR455,AKR1C1,IL15,NFE2L2,TICAM1,PDE1B,AKR1C2,ABHD2,LILRA1,OSM,CCL1,AMIGO1,IRF1,PQBP1,PIK3R2,CUL3,NR2E1,PIK3R1,RAN,MIR493,RXFP2,ACTR2,SHOC2,FZD4,CAPN2,OPRK1,IFI16,SNX10,IFNG,ICAM1,IL17F,CD47,PIK3CA,MIR15A,MIR143,CAMP,P2RY12,PDCD4,GNG2,SMARCA5,SRC,CALY,DAG1,IL18,SST,CSH1,MGARP,KCNJ11,PTGES3,FASLG,LEP,INSIG2,ATF4,PIK3CG,MIR140,EPS8,PDE4B,BACE1,CD58,PHB2,TFPI,WBP2,PDE2A,PML,RPAP2,CHI3L1,CCL2,SYP,FOS,HCLS1,IL2RA,NHERF1,NPPC,MAP2K6,GNA11,GPR75,MRAS,CCL4L1,PIGA,DRD1,WBP1L,CACNB4,NFKB1,MIR16-1,EIF2S1,B3GNT2,IL15RA,CYP1B1,FKBP4,TICAM2,SLC12A2,TRAF6,RARRES2,TLR2,NPTX1,STAT5A,CDK4,XRCC5,TBK1,VPS54,P2RY11,VAMP3,CCL19,PACRG,MT2A,SMAD3,LHB,PLP2,STC1,TFRC,YES1,BIRC2,DUSP1,SLC23A2,CLTRN,PLSCR4,RAP1A,UBE2L3,CRHBP,HNRNPD,WNT2,CD40,RPL3,TMBIM6,CCL23,RALB,DERL2,CCR4,GNB1,SYK,ADIPOR1,SELENOT,STAP1,CREB3,HDAC6,FCGR2B,TESC,NFKBIL1,ATF3,NKX3-1,USP8,GPBAR1,MAVS,HTR1A,RBFOX2,CAV1,IFNB1,SOCS3,EEF1E1,CAV3,MSTN,RUVBL2,STAMBPL1,EFNA5,MEF2C,GPR35,CMA1,HSP90AB1,FKBP1B,ZYX,MIR31,IL4,BRCA1,MIR342,SMAD2,MYD88,GFI1,SOCS5,IL20RB,HSPA5,IFIH1,HTRA2,GABRB2,LILRB4,EGR2,ARL6IP5,GPR22,PSEN1,MIR146A,CD4,CLDN1,IDE,MIR324,CCDC186,MIR149,ATP1A3,PELP1,DEFB124,IL2RB,AKAP12,GLRA1,SOS2,MIR200A,EPHA4,TLR3,CCL5,KCNB1,MIR106B,RORB,SOCS2,ZFAND6,GPR17,IFNAR1,DAPK1,CDC42,IGF1R,CREB1,SFRP1,TUBA1B,TXNDC17,FBXO32,CCL17,PTGER2,TIMP3,LILRB1,CNTFR,RPS6KA4,KLF9,CDK1,SRM,IL12A,HTR2A,BCL10,REN,INPP5K,CCL3,ATP5F1A,YWHAH,OPRM1,NFIL3,STX8,IRF3,IL6ST,SMAD5,CSF2,OS9,CAV2,KDM1A,CTSB,ACTN4,EIF4EBP2,IRF7,SMAD1,OR51E2,IL5,RAP1B,OAS1,CRHR1,RNF126,SHC1,IRF8,GNA14,HDAC5,MRC1,PRKCB,CCR1,SYNGR1,CBL,STAT2,SOX9,CCR5,ERO1A,BAG3,CTNNA1,TADA3,CPEB1,CCL21,MIR20A,GHRL,IL1R2,CYP1A1,LITAF,BRINP3,RAB13,ATP1A2,KLHL15,MIR370,MAP2K3,IL1A,PLSCR3,IL18BP,JAGN1,IL2RG,KCNMB1,AANAT,ATP5F1B,GABRG2,GJB2,SESN3,TWNK,SPP1,SDF2L1,DHX9,GSTM2,NFKBIB,CXCR6,PTPN22,GCLC,SRSF7,ADRB2,SULT1A3,TNFSF18,MTDH,HAND2,CST11,ADTRP,CCL20,CXCL1,CCR7,MAT2A,FOLR2,STAT6,DDIT4,CCR6,MKKS,IKBKB,IL34,GAPDH,EGR1,CHCHD4,SLC6A4,EPO,NR4A2,EZH2,IL3,IL7,NFYB,MIRLET7G,NCSTN,ESR2,CHMP5,PGR,IRAK4,SESN2,JUP,CDKN1B,MLC1,GAB1,KLHL22,UFD1,TSPO,HELLS,RPL23,PTGER4,CCNA2,PPARG,SP1,SLC16A1,CYP7A1,CXCL13,TP53,GNAI3,RRAGA,MDM2,CXCL8,LPAR1,TAF7,BRINP1,IL13,MIR34A,DDX5,LEPR,SOD2,CLEC7A,GPR173,AZI2,SOST,HPCA,ITGA6,HSPA8,GHR,LILRA3,PTPN1,BRINP2,COMT,UGT1A1,TMEM38B,TRIP4,TSHR,ACKR3,P2RY1,DDIT3,TLR4,PTPN11,CCL8,CCL11,KLF4,HSP90B1,GLRA2,SPHK2,TMSB4X,LRAT,CDK9,TNFRSF14,VAMP2,CXCL10,FOLR1,GREM2,SLC25A5,NUP35,RB1,CGAS,SLC22A12,CYP11B1,RAB31,TRA2B,CCL18,PTGER1,ILK,CASP4,RAD23B,CCL25,RPS16,NLRP3,CASTOR2,MIR17,CXCR3,GJA1,CFTR,PDCD1LG2,CSNK2B,HSPB8,CCR2,FOXC2,TIFA,AIF1,INA,CACYBP,SLC29A1,PTGFR,MUL1,XCL1,H2AZ1,IL10,ROCK2,RAF1,CX3CL1,ZC3H15,ADIPOQ,TNF,VAPB,SHMT1,ACTB,CCR3,CYP11B2,PPP1R1B,RPS3,EDA2R,LY96,TRIM6,PHB1,ERLEC1,PDE12,PDIA3,PAQR8,CX3CR1,MIR145,TRAF2,ATP1A1,TRAF1,AVPR1B,CDK5,CXCR1,PTK7,CXCL12,RAB11B,STUB1,DNAJC10,MME,HMGB1,GABRB3,TOP2B,IL1RAP,PYCARD,HRAS,AGER,FBP1,CXCR4,MIR98 |
| 2.736e-16 | -35.84 | Metabolism of proteins | REACTOME pathways | R-HSA-392499 | 1619 | 650 | 10285 | 3229 |
STX5,ETFB,SERPINA1,PMM2,RING1,NSMCE3,SIAH2,RNF5,RAB27A,PSMD14,MAN1A2,RAB29,UBE2B,SPTBN1,CMA1,SLC17A5,PABPC1,UBE2E3,PSMB6,ATP5F1A,PSMA2,SSR3,NRN1,GMPPB,RWDD3,PSMA4,PSMC4,SUMO2,STX17,CCL2,CDC20,PSMB1,EEF2KMT,TRMT112,EIF3J,TFPT,RAB2A,ETFBKMT,H2BC9,DPM2,POMT2,RPS4X,H2AC14,HGS,TFG,CHCHD2,ODAM,RAB3C,NUP153,BET1L,BIRC2,PIGW,EDEM2,FXN,EIF3K,ADAMTS20,CCT8,IZUMO1R,XBP1,VDAC1,UCN,ADD1,H2AX,USP16,RPL3,CALR,TIMM8A,RUVBL1,TIMM17A,SPRN,GNB3,GNGT2,DHPS,CTDSP2,RNF181,HNRNPK,NUP37,MAVS,DPP4,CMAS,LMNA,SENP5,RPL7,MDC1,COPE,EXOC8,F9,RNF20,PCSK2,PFDN5,INO80E,IDE,CLTRN,RPS7,CNIH1,NEGR1,GGCX,SLC25A12,H2BC14,H2AC25,RPL10,RAB3B,EIF2S2,RPL22,UBE2H,TOMM70,FBXW4,SLC25A4,RPS3,GNG5,GH1,PIGC,FUT8,PTP4A2,DNAJB9,SEMA5A,BCS1L,TRAPPC6B,TUSC3,RAB39B,SEC11A,COA4,PSMA1,RPL13A,TRAPPC6A,GRPEL1,TUBB4B,SEC22B,UFD1,GOSR2,PREB,MIR197,SUMO3,VAMP2,RPL28,PSMD1,RAB13,MUL1,CD59,CYC1,RAB11B,ST3GAL4,SPCS3,PDCL,CTSD,DYNC1I1,SMAD4,FURIN,ARFGAP1,USP30,SFTPA1,BCL10,ST8SIA4,PGA4,SRPRB,HSPA8,PFDN1,BET1,B4GALT3,DERL2,GFUS,UBE2A,SEC62,RPS27L,PRND,RPS10,ST6GALNAC3,LEP,ADAMTS10,GALNT4,GOSR1,IGFBP3,CTSC,RPL19,B2M,MIR711,EIF2B3,NAPG,ZBTB17,HSPD1,CHCHD3,H2BC17,DPH6,KDELR2,PCGF2,REN,NOP58,H3C1,RNF139,ACTL6A,OTULIN,SPCS1,RAB23,SPON1,RAB31,EIF4H,RAD23B,MGAT4B,H2BC1,ACHE,TOMM7,TOMM20,THY1,MGAT4A,EEF1G,DPH3,HSP90B1,RNF128,WDR20,NFYB,DCTN6,PSME2,NUP107,PTRH2,MME,SMAD1,RAB5C,RPL24,NUS1,EEF1A1,KLF4,RGS6,NEDD8,EIF4A2,PIGK,CGB8,MYC,FAU,RPL32,TADA3,CTSA,EIF5A2,RABGGTB,EXOC1,SRD5A3,UBE2S,SEC13,SMAD3,ERO1A,RPL27,TAF10,CETN2,NFKBIA,SRP14,TUBA1B,RPL29,SFTPD,FBXL3,RPL10A,DCTN4,PSMB3,SCFD1,EIF4E,GNG10,GMDS,SAR1B,RAB35,PSMA5,SEC63,USP14,CHCHD4,EIF3G,DOLK,ATP5F1B,STX1A,H2AC1,GRIA1,TMEM115,RAB6B,RPS13,RAB33A,HSPA5,APEH,BGLAP,RPS27A,RNF146,CMC4,PAX6,UBE2D3,STT3A,H2AC6,TP53,RAB5A,RPS29,USP3,RAB8B,B4GALT1,UBE2I,RIGI,EIF1AX,METTL21A,BRCA1,ATF3,USP5,ENPEP,GALNT2,RAB6A,NLRP3,TOMM40,GPIHBP1,CST3,CCT7,SAMM50,UBE2K,TAFAZZIN,GNAI3,RAB9B,B4GALT4,F7,BECN1,GNAO1,SLC30A5,PLA2G4B,ADRM1,H2AC13,SEC61A1,UBE2N,F10,RPS16,TUBA1A,BABAM1,RPL6,DERL1,H2AB1,GNAZ,ATP5MC1,RPS20,TOP2B,HSCB,UBB,PDIA6,RAB9A,IGF1,RPS9,GALNT12,RPS2,GNG7,TRAPPC2L,UBE2L3,UBE2G2,RPS11,NTNG2,H2BC12,EXOC3,WRAP53,GNG12,RPS15,FKBP8,PSME1,DNAJC19,NFYA,USP8,VDAC2,H2BC11,DAD1,RPL26L1,KIN,SEC61B,PSMB11,DAG1,LY6H,CEACAM5,DCTN3,ST6GAL1,MGAT1,RPL31,FN3KRP,NAPA,BAP1,RAB1A,ADRB2,RAB1B,NUP50,TOMM6,RPL12,CSNK2B,EXOSC4,TIMM10,EDEM3,GHRL,ALG2,RPL27A,CSNK2A1,DYNLL1,GSK3A,SRP54,FBXW7,PSMB9,NANP,B4GAT1,SEC22A,TRAF6,EDEM1,COX19,CDC73,SSR2,RPL7A,RRAGA,ARFGAP3,TIMM8B,SKIC8,SRPRA,EIF4B,PRL,COPZ2,TMED9,PSMD12,CFTR,TNFAIP3,USP2,FPGT,RAB30,RPSA,RNF152,TRAPPC1,RPL37A,GANAB,TMED7,RAD21,RAB14,F2,MSRB3,PML,RPL26,MTX2,RPL39,CHST10,EEF1B2,ST3GAL5,MIA2,PSMD10,GNG13,SPTAN1,ARCN1,PTEN,BACE1,SIAH1,EXOSC8,SENP8,EXOC5,CXXC1,ACTB,TAB1,BIRC5,PROS1,HNRNPC,PSMD4,RAB32,LARGE1,MVD,RPLP1,GPAA1,EIF2S1,CTNNB1,H2AC4,SLC35A1,RPL15,KDELR1,HDAC3,NUP62,B3GNT2,RPS28,RAB33B,SFTPC,GMPPA,LYZ,TIMM23,SHC1,SEC61G,RPN1,RPS5,RPL23A,SUMO1,PSMB2,NUP42,FOLR2,ALG11,GNG11,FOLR1,RPS24,PSMC1,SNX3,DOHH,CXCL8,COG1,SYVN1,TRAPPC4,GALNT1,B4GALT6,MBD5,ST3GAL1,EXOSC1,TMED3,PSMD7,ATP6AP2,GNG2,YIF1A,RAB11A,YKT6,IFIH1,RPL23,CPE,ALPL,USP15,TNKS,SEC61A2,TXN,PSMC5,SLC30A7,MSRB1,TIMM21,PSMB10,POLB,ACO2,SMAD2,UBE2W,EIF3D,MIR7-1,PSMA3,PSMB5,TTR,OS9,PSMD3,UAP1,PSMB7,DNAJC3,FKBP14,TRAM1,NEU1,CCNA2,NUP35,TOMM22,MIR24-1,GNB4,CCT5,CD52,PCNA,RPLP0,RPS26,TNKS2,EXOSC3,ATF4,RPS17,MPDU1,EIF2B2,DPAGT1,IGFBP4,TCP1,PSMD6,GFPT1,RAB37,RPLP2,RPL8,UBE2D1,MITF,INO80C,GNG3,RPS14,KLK3,RNF103,RAB4A,DDIT3,DCP2,PIGA,RAB3D,PFDN2,GNAI2,H2AZ1,EIF5B,JOSD1,H2AC7,TBCE,SEC22C,TGFBR2,UBA52,LY6G6C,GNB1,RAB19,RPS12,VCPKMT,RPL4,EXOC2,RPS23,EP300,PMPCA,OTUD7B,INHA,PIAS1,PFDN6,PFDN4,GCNT3,RPL35,TIMM13,CCT2,EIF3E,RPL17,MAT2B,UCHL3,RPL9,DYNC1I2,STAMBP,RPL18,MDM2,PLG,EIF2B5,DNAJC24,GRPEL2,RAB3A,TRAPPC3,RCE1,RNF40,ARF1,RPL10L,AR,TRAF2,RAB22A,C1GALT1C1,LMAN1,PSMC3,RAB18,ADAMTS1,SEM1,TOP1,ETF1,PSMB4,SEC23A,LHB,ST3GAL2,SPCS2,PSMA6,SSR1,TRAPPC10,ST8SIA5,GNPNAT1,RPL35A,ALG5,SRP72,SLC35C1,GALNT17,STAMBPL1,PDIA3,PHC1,ARF4,EEF2,METTL22,SULT1A3,DPH5,USP13,ITM2B,COX17 |
| 2.767e-16 | -35.82 | CHD3 (chromodomain helicase DNA binding protein 3) | protein interactions | 1107 | 749 | 312 | 19454 | 5460 |
RPL17,PHF1,HNRNPK,CSE1L,KPNA2,H3C1,DHX9,RPL3,PSME1,BHLHE40,NEFL,RBM34,IK,CBX3,DDX42,ZMYM3,TP53,RPSA,ATP5PB,STRBP,CDC5L,TMPO,DKC1,RPS27L,SHPRH,BRMS1L,RPS16,GATAD1,ALYREF,SYNCRIP,RPL10A,RPS2,TNFRSF14,AKAP8L,KPNA1,RPL24,H2AC4,SNRNP70,GAPDH,API5,CSNK2A1,RBM17,HSPA5,BCL6,RGS2,KDM1A,WDR3,RPS15,HDAC3,RNF113A,NLE1,RPL27,DDX46,LUC7L3,TFIP11,HEXIM1,ZNF326,MAFG,FGF13,SUMO1,SPTBN1,UBA3,TRIM54,LIG3,ZNF330,CREB1,RPS3,UQCRC2,SF3B6,RRP7A,IGF2BP1,EIF3G,SPOP,RPS17,H2BC9,RPL7A,SMARCA5,POLDIP3,PAX6,HNRNPDL,CCAR1,RPL28,RPS4X,RUVBL1,SATB1,VDAC1,ZBED1,HNRNPF,ACTR1B,RTCB,EWSR1,MYO1B,PABPC1,TOP2B,RPL31,RPL18,RPS23,SMARCB1,MTA2,TUBB4B,RPS7,TUBA1A,SOX2,SUPT5H,DHX38,HSP90AB1,LYAR,SNRPA1,SUMO2,RAB1B,FAM98A,RPS10,HNRNPL,EIF2S1,EED,S100A8,ZHX1,SRSF1,RBM5,FABP5,SIN3A,DDX1,NGDN,RPL6,DDX50,BAZ1B,ZBTB5,SAP18,PHB2,STAU1,HNRNPA0,TRA2B,FXR2,DDX5,LCN1,EP300,SF3B1,HSPA8,XRCC5,RPS28,DDX39B,NCOA5,CTBP1,RPL27A,ESR2,RPL10,LRIF1,SNRNP40,MATR3,ATP5F1B,ZMYM2,VDAC2,PHF12,PRSS1,NSA2,YAE1,PSMD14,H1-10,CHTOP,FTSJ3,SNRPB,CPSF2,HNRNPC,HNRNPAB,CREBBP,MSH6,RPS13,MRPL22,NOC4L,THRAP3,CDK2AP2,HSD17B10,RPL23A,NKRF,SRP72,ILF2,RPL15,CD2BP2,AURKAIP1,EEF1A1,DDX39A,MTA3,ZBTB2,TOP1,PWP2,MYBL2,KRR1,RPL12,EPOP,MOV10,BRIX1,FABP4,AATF,MBD3,PIAS1,RPL4,TTR,GTF2I,H2BC12,MTDH,RETREG2,PNO1,ZKSCAN1,PRPF4,RPLP0,HNRNPH3,FBP2,LMNA,JUP,KLF12,MX1,RPS14,SF3A1,RPL22,VIRMA,NR1H2,RPL13A,ZNF622,RPS12,RPS20,UBE2I,ALB,RTRAF,TUBA1B,METAP2,EIF4A3,CTTN,ENO1,PELP1,IVNS1ABP,NONO,AR,PPP1CC,RPL26,ATP5F1A,PYCR2,ZNF687,RAD21,RFC3,SSRP1,RPS27A,G3BP1,RBBP7,ZNF592,SRSF7,RPS24,GADD45A,HNRNPA2B1,SLC25A5,TRIP4,HSPD1,CPE,RBPJ,RPS11,RPN1,EZH2,LGR4,SAP30,RPL29,OTUD6B,JUN,RAF1,DHX15,CCAR2,RPL7,HYPK,NOP58,KRT8,RPLP2,HP1BP3,RPLP1,PHB1,MRTO4,RPL9,RPL8,RPL23,LYZ,NAB2,HNRNPD,DDX23,HNRNPA1,DPY30,PRPF19,COIL,PTN,SAT1,ATP5IF1,MYL6,SLC25A3,ADNP,USP39,ATP5PO,APOBEC3C,KLF3,PPP1CB,ERH,RPL19,ACTB,RPL35,RBBP4,TUBB,RPS9,SNRPD1,SNRPD2,RAN,CPSF1,RPS5,HSP90AA1,LMNB1,MCM3,PRPF31,SMARCE1 |
| 2.798e-16 | -35.81 | FBP1 (fructose-bisphosphatase 1) | protein interactions | 2203 | 343 | 167 | 19454 | 5460 |
TPM3,HDAC6,NFKB1,KARS1,RPL10A,RPS2,RPL24,SMCHD1,BCL10,EIF5A2,RB1,RPL32,SYNCRIP,SSBP1,RPL12,CDC5L,TMPO,MYL12A,TOP1,PLG,RPS16,RPL35A,ACTR1A,EEF1A1,FBP1,SLC25A24,ILF2,CAPZA2,KLRC2,DHX9,RPL23A,RPL3,ILDR1,PPP1R12A,RPL17,RPS13,ARF4,HNRNPK,THRAP3,GIMAP2,DYNC1I1,LSM4,TUFM,RPL26,ATP5F1A,SUB1,RPL7A,SLC25A1,CSGALNACT1,ATP1A1,STK11,PIM2,RPS12,ALB,RPS20,ENO1,CTNNA1,UQCRC2,RPS3,RPL22,UQCRQ,TXNDC12,TXN,RPS14,LUC7L3,CYC1,RPLP0,STOM,LMNA,RPA2,FBP2,H2BC12,PRDX6,TLR2,FLCN,RPL27,RPA3,HSPA5,FBXW7,RPL4,EIF5B,NME4,RPS15,GTF2I,QPCTL,HNRNPA1,XPO1,RPL6,IFI16,HMGA1,RPL23,BCL2L1,DDX1,HNRNPD,AGR2,RPLP2,RPLP1,MAGED2,SRSF1,RPL8,HSP90AB1,DHX15,PPIA,SNRPD3,RPL7,RPS10,HNRNPL,EEF2,ISG15,RPL29,CSNK1E,RAF1,RPS23,RPS11,NME1,RPN1,EZH2,SRSF7,EWSR1,TRIM21,MYO1B,ABCF1,PABPC1,HNRNPA2B1,LSM14A,SLC25A5,RPL31,HSPD1,RPL28,RPS4X,KCTD17,H1-6,G3BP1,HNRNPF,MCM3,RPS5,RPS26,MYO6,CIRBP,RPS9,PRMT5,RPL37A,NFKBIA,SNRPB2,ERH,RPL19,ACTB,TUBB,RPL35,ATP5F1B,MATR3,DHRS4,RPL27A,WDR77,MYL6,EIF4B,DDX5,HADHA,HSPA8,XRCC5,SPECC1L,BMPR1A,TIGD7,PHB2,HNRNPA0,FXR2,MLH3 |
| 2.845e-16 | -35.80 | CTCF (CCCTC-binding factor) | protein interactions | 10664 | 421 | 196 | 19454 | 5460 |
RPS28,HIRA,DDX5,EP300,HSPA8,PHB2,STAU1,FXR2,MRPS7,SAP18,RPL27A,SYK,NEK7,VDAC2,ZMYM2,SNRNP40,CAVIN2,ATP5F1B,RPL10,ESR2,MYC,RPL39,H1-10,H1-1,SERPINH1,RPS26,PABPC1,TOP2B,RPL31,RUVBL1,KRAS,PAX6,RPL28,RPS4X,RPS7,EEF2,H1-3,SOX2,TRAF2,RPL18,RPS23,ZRANB2,SRSF1,SIN3A,MAGED2,EED,LYAR,RPS10,HSP90AB1,RPL6,RAB5C,IFI16,DDRGK1,RPL27,RNF113A,RPS15,HSPA5,ZNF326,SSR1,LUC7L3,ZBTB33,RPS3,MACROH2A1,EIF2S2,SRP54,SEC61A1,PHAX,FGFBP1,CSNK2B,MRPS28,RALA,SRPK2,CDC20,RPL7A,RPS17,EIF3G,MAP1B,DHX9,ABCE1,RPL3,TMEM33,KPNA2,H3C1,RPL17,RPSA,ZMYM4,H2AX,SURF4,RPL32,SYNCRIP,MRPS9,RPS27L,RPS16,CAND1,SURF6,KLF9,RPL24,H2AC4,SMAD4,USP15,RPL10A,RPS2,KPNA1,NOP53,SLC25A3,MYL6,RAN,EIF3K,RPS9,RPL37A,RBBP4,RPL35,ERH,RPL19,CUL3,RPS29,ZNF668,ZCRB1,RPS5,SLC25A5,HSPD1,SRSF7,RPS24,RBBP7,RAD21,SRSF4,RAF1,FAF2,RPN1,EZH2,RPS11,RPL9,RPL8,RPLP2,HP1BP3,RPLP1,RPL7,MRPS35,RPL23,LHX2,FADS2,SIRT7,RHOU,MTDH,SMC4,FBXW7,RPL4,HMGB1,NPM3,DGCR8,UTP23,RPS14,KLF12,ZMYM6,MRPS34,LMNA,RPL26L1,RPLP0,RPS12,RPS20,CMBL,PRKRA,RPL13A,RPL22,VIRMA,TECR,NONO,TUFM,RPL26,ATP5F1A,SFXN1,NKRF,RPL23A,RING1,THRAP3,EIF3E,MDC1,RPS13,ARF4,MRPL11,RPL15,APOBEC3D,AURKAIP1,LBR,LLPH,SRP72,KRR1,H2AZ1,SMAD3,RPL12,CGAS,MAPRE2,RPL35A,ZBTB2,CD9,BRD3 |
| 2.849e-16 | -35.79 | PUF60 (poly(U) binding splicing factor 60) | protein interactions | 22827 | 359 | 173 | 19454 | 5460 |
MIR145,CASC3,FBXO7,AR,DNAJC8,MIR16-1,STUB1,CCNF,GSK3A,UBE2I,METTL14,STOM,HNRNPH3,RPS14,SAP30BP,SF3A1,MREG,MIR1-2,CDK7,NUCKS1,FBXW7,RPA3,PPM1G,SIRT7,MIR205,MIRLET7I,MIR34C,CRBN,MIR34A,MOV10,HDAC6,MIR106B,MIR25,MIR20A,ILF2,PPME1,RAD23B,CD2BP2,MIR15A,MIR200C,EEF1A1,THRAP3,OLA1,FAF1,EMC2,PPP1R16A,YWHAZ,MIR363,ILK,NIBAN2,CUL3,SIAH1,LAMTOR3,MIRLET7D,SNRPB2,SNRPD1,SNRPD2,ARCN1,CDKN1A,MIR106A,PSMA3,DDX23,MIR1-1,HNRNPA1,TRA2A,ZNF207,SRSF10,DHX15,FOLR1,MIR7-2,MIR141,FTHL17,SF3B5,SNRPE,B3GNT2,RAF1,KHDC4,E2F4,GUK1,G3BP1,UBE2A,ZYX,HSPD1,ARGLU1,SRSF8,ERP29,RC3H2,IGF2BP1,UBE2H,SUGP1,RAB2A,EIF4H,SRPK2,SF3B6,SDCBP,RPA2,BORCS5,UBE2M,MIR21,HEXIM1,MIR7-1,DDIT4L,MIR34B,MPV17,CFTR,UGP2,MIR107,MIR29A,BAP1,DDX46,MIR10B,RNF113A,SNRNP70,RBM17,COPS5,GAPDH,CAND1,MIRLET7G,TMPO,MIR429,SYNCRIP,IK,TAF2,MIRLET7C,MEPCE,MIR16-2,MAP1B,MIR200A,MIR9-3,MYC,HNRNPC,PAPOLA,SNRPB,MATR3,APEX1,MIRLET7B,SF3B4,ZC3H14,UFL1,STAU1,SNRPA,SF3B1,HSPA8,EP300,AGR2,MIR31,MIR221,MIR140,DDX50,IFI16,MIR143,RPL6,YWHAG,MIR29C,DDRGK1,HNRNPL,SNRPA1,SNRPD3,MIR9-1,SRSF1,EED,MIR214,PIR,SMNDC1,TOP3B,SOX2,MIR222,KRAS,HNRNPF,XPNPEP1,MIR155,PABPC1,EWSR1 |
| 3.061e-16 | -35.72 | RPS16 (ribosomal protein S16) | protein interactions | 6217 | 677 | 287 | 19454 | 5460 |
MPHOSPH10,ESYT1,SPATS2L,EMC4,HDAC6,APOBEC3F,RPL35A,EIF2B5,CDK9,NOP9,RPL12,SRPRA,RCHY1,ACTA2,KRR1,PRR3,LLPH,ILF2,SRP72,CCDC47,FBP1,MAP1LC3B,EEF1A1,RPL15,HUWE1,VRK1,NOC4L,RPS13,RIGI,EIF3E,NKRF,HAPSTR1,RPL23A,IGF1R,ASCC1,CASC3,FBXO7,RPL26,TUFM,AR,ZNF622,RPL13A,DYNLT3,VIRMA,RPL22,CCNF,EIF2AK2,POP7,METAP2,EIF4A3,RTRAF,TRIM24,RPS20,RPS12,METTL14,RPL26L1,RPLP0,RARS1,ZNF574,RPS14,PIP5K1A,EDF1,CDK7,EIF3J,FBXW7,RPL4,HMGB1,PIAS1,AATF,BRIX1,RPA3,PRPF4,SIRT7,NOG,PNO1,MTDH,SQSTM1,DDX23,ZCCHC9,AHSA1,RSBN1L,RPL23,EIF3D,RPL7,RPL8,WDR6,FOLR1,RPL9,PHB1,HP1BP3,RPLP1,RPLP2,EZH2,CHMP4C,BZW2,RPS11,B3GNT2,E2F4,RPL29,UFM1,EMC8,TRIM37,SRSF4,GTF3C3,RPS27A,EIF2D,RAD21,RFC2,TRIP4,PPAN,RPS24,BRCA1,ZCRB1,HSP90AA1,RPS5,RIT1,CUL3,CUL2,ZNF668,RIOK2,RPS29,EIF4A2,RPF1,RPL35,RPL19,PRRC2A,ARF1,ZNF22,FAU,EIF3K,RPL37A,SEC61B,RPS9,EMC9,LARP4B,TBC1D17,H1-5,CDKN1A,YTHDF1,G3BP2,CCDC86,TUBG1,SNRNP70,RPL24,NOL12,RPS2,RPL10A,KARS1,ENY2,CMSS1,CSNK2A1,COPS5,CD81,E4F1,API5,CAND1,FZR1,RPS27L,DKC1,RBM42,CDC5L,SURF6,RPL32,ALYREF,TFCP2,UBL4A,STRBP,SRFBP1,KBTBD4,TP53,RPSA,H2AX,NEDD8,SRPRB,MEPCE,RPL17,EIF1AD,RPL3,ABCE1,POC1B,DHX9,SPOP,EIF3G,RC3H2,PDCD4,IGF2BP1,EXOSC1,UBE2H,RPL7A,RPS17,RPL10L,SMURF1,SRPK2,PSPC1,RPS3,SEC61A1,SRP54,EIF2S2,RPA2,WWP1,HEXIM1,DYRK2,TFB1M,GTF3C4,CFTR,FGF13,RPS15,WDR3,EIF4E,ZC3H15,MARS1,HSPA5,RPL27,BAP1,EXOSC4,LSM12,RNF113A,AGR2,DDX1,DRG1,CNOT2,DDX50,RPL6,WWP2,RIOX2,XPO1,CTNNB1,DDRGK1,BTF3L4,EIF2S1,NOB1,FAM98A,RPS10,LYAR,HSP90AB1,EED,SEC61G,RPS23,RPL18,TRMT1L,TOP3B,H1-3,SOX2,EEF2,RPS7,KRAS,RPS4X,RPL28,RPL31,PABPC1,TOP2B,RTCB,FTSJ3,H1-10,RPS26,ICAM1,H1-1,NSA2,MYC,SFN,RPL39,BTF3,USP16,TAX1BP1,RPL10,CMTR1,ADSS2,EIF4B,NUFIP2,PIH1D1,RPL27A,MTF1,PAFAH1B1,FGF17,UFL1,HNRNPA0,EIF1B,FXR2,TRA2B,STAU1,EEF1G,SSR3,PYM1,RFC4,RPS28,HSPA8,DDX5 |
| 3.259e-16 | -35.66 | HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10) | protein interactions | 3028 | 416 | 194 | 19454 | 5460 |
TOMM40,MCM3,MCM4,MTG2,AUH,RAB11A,CUL3,PMPCA,BAX,HTRA2,MYO6,RHOB,DCAF4,ENO2,GNB1,PRDX2,TENT5C,PRDX3,DET1,PGRMC1,FKBP1A,MYL6,HADHA,PSMC1,COIL,G3BP2,UCHL3,HSCB,DUSP26,EIF3D,PRPF19,PSMD3,MRPS26,RHOG,UBE2D1,HBA1,TRAF6,GATD3,ARL11,PHB1,CACYBP,EGLN3,PPIA,NOP58,CCAR2,PPP2R1A,FEN1,CHMP4C,BZW2,HINT2,COX8A,HSPD1,SCYL2,HNRNPA2B1,PSMD12,GUK1,RBBP7,TRAF3IP2,ATP5F1A,TUFM,FKBP1B,PIP4K2C,ARFGAP3,GLTP,ACAT1,MSN,PTEN,CCNF,EIF4A3,ENO1,CTNNA1,COPE,RHOJ,ATG16L1,PSMC4,EEF1E1,HNRNPH3,WTAP,MTRES1,CDK1,JUP,H2AC7,HSP90B1,RTN4,GPX4,RPA3,PIAS1,PDHB,HDAC6,ATP1B1,GRSF1,EMC4,ISYNA1,PSMD7,PSMB1,AIFM1,RCHY1,DBT,CD2BP2,EEF1A1,AURKAIP1,UBE2V1,ILF2,ACTR2,TAGLN3,FAF1,SFXN1,GLUL,HUWE1,HSPE1,PSMD1,MYC,HNRNPAB,MDH1,SERPINH1,CCT2,CHTOP,PSMD14,SMU1,TACO1,DLST,ESR2,TAGLN2,PSMD6,SYK,TOMM22,PIH1D1,ADSS2,ACAA2,HDAC5,XRCC5,UFL1,STAU1,EEF1G,PPIB,DDRGK1,WWP2,ASB1,AGR2,FABP5,PSME2,CCT7,RHOH,SUMO2,SOX2,EEF2,PDHA1,RUVBL2,PDIA6,RTCB,PABPC1,CCT8,FKBP2,HNRNPDL,RAB8B,KRAS,RUVBL1,MAT2A,NAA50,CALU,UBE2H,ATP1B3,PSMC5,PITPNB,CSNK2B,SF3B6,BUB3,PLP2,CDC42,UBE2M,HEXIM1,HBB,FGFR1,GFM1,PRDX6,BAP1,TOMM20,COPS5,KARS1,RPL10A,H2AC4,TMEM70,AKR1B1,EEF1B2,SSBP1,ALYREF,COX4I1,MYL12A,DKC1,FZR1,CAND1,H2AX,ARPC3,MEPCE |
| 3.313e-16 | -35.64 | U2SURP (U2 snRNP associated SURP domain containing) | protein interactions | 23350 | 325 | 160 | 19454 | 5460 |
SKA3,SMNDC1,SF3B5,SNRPE,E2F4,SUPT5H,H1-3,MIR222,CSTF2T,KRAS,H1-6,TRIM37,MIR155,SRSF4,RPL31,HSPD1,MIR206,TRIM21,TRIM11,SRSF7,DDX23,MIR31,DROSHA,MIR221,MIR1-1,IFI16,WWP2,MIR143,MIR29C,DDRGK1,TRA2A,HNRNPL,RPS10,TRIR,COMMD6,MIR9-1,SNRPD3,SNRPA1,DHX15,WIF1,FOLR1,RBM5,MIR7-2,SRSF1,FBXO32,RFX5,MIR214,PPARG,LARP4B,MFAP1,H1-5,PABPC5,FGF17,ETF1,UFL1,MIR106A,SF3B1,COMMD2,EP300,HADHA,TERT,ZCRB1,MIR363,RIT1,H1-1,MYC,CUL3,MIR98,SNRPB,RPL35,FBXO22,MIRLET7D,SNRPB2,SNRPD2,SF3B4,SNRPD1,MIRLET7B,GTF2F1,DDX42,NUPR1,TBC1D4,TBK1,FBP1,TP53,RPSA,MAP1LC3B,CD2BP2,APOBEC3D,MIR200C,RPL15,CTNNBL1,TGFBR2,PSMB10,MIRLET7C,MDC1,SNRPG,RIGI,HAPSTR1,DHX9,SMCHD1,SNRNP70,RPS2,MIR34A,H2AC14,RBM17,COPS5,CAND1,RPS16,SPPL3,MIRLET7G,MIR429,DKC1,CDC5L,MIR106B,KRR1,MIR25,RPA2,LMNA,GRM2,METTL14,RPLP0,MIR21,MIR7-1,HECTD1,SF3A1,MIR34B,FGF13,RPL4,MIR7-3,MIR107,RPA3,PPM1G,BAP1,MIR10B,DDX46,SIRT7,MIR205,MIRLET7I,RNF113A,MIR34C,SPOP,RC3H2,MIR145,UBE2H,SUGP1,RUNX1,ANAPC15,DNAJC8,USP14,AR,YES1,SRPK2,VIRMA,SF3B6,CCNF,RPS3,CSNK2B,GSK3A,SGTA,MACROH2A1 |
| 3.665e-16 | -35.54 | PDHA1 (pyruvate dehydrogenase E1 subunit alpha 1) | protein interactions | 5160 | 727 | 304 | 19454 | 5460 |
SLC16A1,RPL3,MRPS18B,ABCE1,PALM2AKAP2,MAP1B,SLC25A11,ATP5PF,PDE12,H3C1,NUP107,HADH,METTL15,ATP5PB,TP53,MTCH2,GFM2,SLC25A24,NUPR1,FURIN,TFRC,IK,ACADSB,CAPZA2,ADD1,COQ8A,MRPS9,SSBP1,SDHB,COX4I1,MGME1,RPL32,ALYREF,MYL12A,TMPO,SURF6,MIF,TPM3,LYPLAL1,KARS1,ACOT8,COX5A,RPL10A,TRMT5,H2AC4,LSM12,TWNK,DLAT,GFM1,RBM23,TRIM3,PML,GRPEL1,MARS1,NME4,MRPL41,MRPL10,CFTR,UBE2M,HECTD1,CYC1,SPRYD4,H2BC11,QRSL1,IDH2,MRPS28,PTPMT1,MACROH2A1,UQCRC2,PSPC1,SUCLG2,STAT5A,NDUFAF2,SMARCA5,GSTK1,ATP1A1,OAT,MRPS16,MYO1B,RUVBL2,CCT8,PABPC1,RPL28,TFG,POLDIP3,HNRNPDL,CHCHD2,KGD4,VDAC1,EEF2,TOP3B,ETFB,MTA2,NDUFA12,NUDT19,H2BC1,PDHA1,CORO1C,STX5,HDHD5,FUBP3,UQCRH,PNPLA8,EIF2S1,RAB1B,HNRNPL,ETFRF1,IFI16,RAB5C,CBL,HSPB1,AK2,NGRN,MRPS7,UFL1,NDUFS2,PRCP,EEF1G,PHB2,ADRB2,DHRS4,ISCU,MRPL12,TOMM22,NUP62,ZC3H14,PPT1,UBAC2,MRPL13,VDAC2,TACO1,CCDC90B,DLST,MTG1,DES,ESR2,ATP5F1B,ATG101,MYC,HNRNPAB,LDHB,SERPINH1,CCT2,MRPS25,RBM27,H1-10,CHTOP,HSD17B10,EMC2,RAB1A,SLC25A10,SFXN1,PQBP1,FASTKD5,SMN1,RIGI,ABHD10,HUWE1,HSPE1,DNAJC30,THRAP3,LBR,PPIF,UBR7,BCS1L,CMPK1,MRPL11,ILF2,GINS4,NDUFS3,LDLR,TES,RPL12,AIFM1,ATP5PD,DBT,CDK9,CWC15,MRPS23,MRPL24,DERL2,THOC1,TOP1,HDAC6,ATP1B1,GRSF1,CALR,LAMTOR2,EMC4,POR,RPA3,NCDN,SIRT7,CRYZ,MRPL20,POLDIP2,GTF2I,PPP1R2,PDHB,UQCRC1,LIAS,PCK2,EEF1E1,SEC22B,RARS1,HNRNPH3,WTAP,MTRES1,MRPS34,LMNA,COX6C,HSP90B1,PTEN,MSN,ACAT1,CTNNA1,CTTN,TECR,UQCRQ,MGST3,LDHA,RPL13A,ATP5F1A,TUFM,HMOX2,PYCR2,NRP1,HINT2,COX8A,MRPS11,HSPD1,SLC25A5,PREPL,BCKDK,NDUFA4,THNSL1,MRPS17,FLOT1,EMC8,G3BP1,ETFA,ACTN4,CYB5R1,RAF1,HSDL2,NAA15,RPN1,CHMP4C,NDUFS6,HP1BP3,ATP6V1A,GATD3,PHB1,NDUFS8,EGLN3,NUP35,NOP58,INA,MMUT,HNRNPA1,PDIA3,PRPF19,MTRF1,CLPX,BABAM1,STOML2,MRPS35,HAX1,MRPS26,RHOG,ATP5IF1,HADHA,EXD2,HSCB,CYFIP2,IDH3B,PRDX3,TIMM29,AGTRAP,SLC25A3,ATP5PO,CYB5R3,CHCHD3,NDUFAF4,MRPL23,RPL35,TUBB,ACTB,AK3,TOMM40,MCM3,ACO2,AUH,MTG2,PMPCA,TMED4,PYCR1,CUL3,RAB11A,CNIH4,LMNB1,WDR20,MYO6,NOA1 |
| 3.772e-16 | -35.51 | PARK7 (Parkinsonism associated deglycase) | protein interactions | 11315 | 328 | 161 | 19454 | 5460 |
ACAA2,PIH1D1,ARCN1,ANXA7,MAPKAPK5,PRDX3,NEK7,PPP2R2C,BOLA2B,EEF1G,SAP18,PEBP1,DUSP9,DNAJC3,DDX39B,ATP5IF1,HADHA,YWHAZ,CHTOP,BRCA1,BAX,MYC,ACO2,LDHB,CUL3,AK3,OTUD7B,PRDX2,LGALS3,TAB1,SPINDOC,TENT5C,RBBP4,APEX1,CLIC4,ARF1,PIR,EZH2,PDHA1,NGB,MTA2,ANP32A,LYPLA1,PPP2R1A,ISG15,SOX2,EEF2,RBBP7,VDAC1,SAR1B,ANP32B,IMPA2,HNRNPDL,NDUFA4,PABPC1,CCT8,HINT2,PDIA6,RHOG,AGR2,TRAF6,PPM1B,YWHAB,NQO1,BCL2L1,MTRF1,HMGA1,BABAM1,SELENOW,WWP2,PPIB,DDRGK1,CTNNB1,SUMO2,EGLN3,PPIA,DUSP6,GATD3,RPA2,IDH2,UBE2M,GSTP1,SEPHS2,SUMO1,DDAH1,SPR,NDUFAB1,CFTR,PDHB,MBD3,POLDIP2,HSPA5,CRYZ,BAP1,SOD1,PRPF4,PML,PGK1,PRDX6,SQSTM1,RNF113A,GPX4,PPTC7,NRP1,OAT,UBE2H,CFL1,CFL2,NONO,AR,TXN,COPE,LDHA,TMOD3,DDAH2,STUB1,OPTN,CCNF,ENO1,PTEN,TRIM24,UBE2I,NDUFS3,ILF2,SOD2,MSRB1,CMPK1,TP53,GLRX5,WBP11,DUSP1,PGM1,THRAP3,DUSP19,RIGI,MPST,MAP1B,RAB1A,ATP5PF,MRPS18B,HINT1,HSD17B10,H2AC4,TMOD2,CALR,SELENOS,PGAM1,PPM1D,TPM3,FZR1,MIF,MYL12A,DKC1,ZBTB2,MRPS9,HDHD3,SSBP1,CD274,ALYREF,DSTN,RAC2 |
| 3.982e-16 | -35.46 | RAD18 (RAD18 E3 ubiquitin protein ligase) | protein interactions | 56852 | 455 | 208 | 19454 | 5460 |
SPTBN1,RPA2,ZNF501,LUC7L3,TFIP11,UBE2M,NBN,LIN7C,MARS1,SUB1,SMARCA5,SUGP1,TRIM23,CALU,ATP1A1,DTL,ZNF330,MACROH2A1,EIF2S2,RBMX2,CSNK2B,BUB3,DYRK1A,SRPK2,PPP1R10,STRBP,ZMYM3,CAPZA2,SIX5,IK,CHAMP1,CDK8,CBX3,CERK,TAF2,SNIP1,CSE1L,KPNA2,SNRNP48,H3C1,CAPZA1,SRSF12,USP2,RBM17,TCEANC2,KARS1,TPM3,CSNK2A1,TMA16,H2AC4,RPL10A,RPS2,CDK12,ALYREF,MRPS9,NKAP,SHPRH,CDC5L,MYL12A,SLC38A2,RBM42,CD59,NCOA5,SNRPA,ARRDC3,ZNF692,TRA2B,MRPS7,SAP18,CPSF2,H1-10,H2AZ2,ZMYM2,SMU1,SNRNP40,TAX1BP1,ATP5F1B,APEX1,H1-3,ZRANB2,MTA2,TOP2B,RPL31,RTCB,MYO1B,RUVBL2,RUVBL1,CCAR1,SIVA1,BAZ1B,CTNNB1,XPO1,CRTAP,DDX1,RBM5,MAGED2,CORO1C,WDR82,SNRPA1,TCP1,MYL12B,SAP30BP,CPSF4,H2AC7,TOX4,MACROH2A2,RARS1,PRPF4,RPA3,PPIH,SQSTM1,BRIX1,DNAJC8,PPP1CC,RUNX1,TXNIP,PPIG,CDC73,EPHA2,CTTN,TUBA1B,CTNNA1,TRIM24,UBE2I,SYT2,RTRAF,YES1,MAGOHB,TMOD3,PDCD5,JUNB,GNAI2,UBB,JPH4,CD2BP2,EEF1A1,MAGEA4,UBE2B,ACTR2,H2AC25,THRAP3,CTNNBL1,CTNND1,FAM133B,IRF9,SLC2A1,BRD3,RCHY1,H2AZ1,SRP14,TOP1,MRPS23,CAV1,AKAP17A,PPP1CB,H2AC1,USP39,APOBEC3C,MFAP1,HADHA,PSMA3,COIL,CFAP20,RBM15B,MCM3,PRPF31,BRCA1,PARP2,GNG12,CPSF1,SEC61B,CDC7,ACTB,RPL35,RBBP4,GNB1,TNPO3,USP5,ZNF263,TULP3,ACTN4,RPN1,SART3,SF3B5,EIF1AX,ARGLU1,HSPD1,SRSF8,BAG2,PCNA,RBBP7,ANP32B,PCGF6,RFC2,SSRP1,FLOT1,SRSF4,UBE2A,TRIM8,ZNF207,TRA2A,DDX23,SKIC8,HP1BP3,XPO5,TSG101,SPTAN1,NOP58 |
| 4.075e-16 | -35.44 | UBQLN2 (ubiquilin 2) | protein interactions | 29978 | 780 | 322 | 19454 | 5460 |
TOM1L1,PSMB6,MATR3,TAGLN2,PSMD4,ATP5F1B,TAX1BP1,MBL2,PSMD6,TIMM21,SF3B4,LMBR1L,ICAM1,CCT2,H2AZ2,PSMD14,PSMD1,UFD1,SNRPB,HNRNPC,LDHB,PSMA4,GNB4,NDUFS2,EYA3,DGCR6L,EEF1G,HSPA8,SF3B1,ARRDC3,LCN1,RFC4,HERC3,XRCC5,PLAA,SEC62,TOM1L2,MTMR6,RPL27A,PSMB3,FGF17,PEG10,HSP90AB1,CCT7,TCP1,CD63,DDX1,AGR2,PPIB,TAX1BP3,FKBP2,TFG,PSMA2,PSMA1,RUVBL1,RUVBL2,EWSR1,FAM168A,PABPC1,LSM14A,CCT8,ZRANB2,GNAQ,CRKL,HGS,RPL18,TUBB4B,PSORS1C2,PDHA1,TRAF2,TUBA1A,EEF2,CSTF2T,MIEF1,OR4N2,SMURF1,MYG1,DUSP3,BUB3,ADRM1,TXNDC12,EIF2S2,PSMC5,SRP54,SGTA,RPS3,PSMA6,IGF2BP1,ATP1A1,OAT,CALU,EIF3G,ATP1B3,TIA1,ST13,TRIM32,PSMB2,MARS1,HSPA5,LITAF,HNRNPH2,GHRL,ARFIP1,SMG5,APMAP,RPA2,IDH2,ILVBL,TMPO,CD99L2,FZR1,FCHO2,PNMA3,RNF128,EEF1B2,TMEM123,AMY2B,DEFB115,ZFAND2B,PIANP,GAPDH,PCYT1B,DHRS7,EDEM1,SMIM11,MPST,NEDD8,PDE12,PSMA5,KPNA2,CSE1L,TOLLIP,HNRNPK,RAB13,SOD3,RPL3,DHX9,IDH1,TRAFD1,DDR1,SLC25A11,PAQR9,PSMC3,PLAAT3,TFRC,TMEM31,MINDY3,GPR162,ZMYM3,SNAP29,NPVF,PREB,MTCH2,INSIG2,TP53,CDK4,FAM162A,PRDX2,DYNLL1,TUBB,LGALS3,TAB1,AP2M1,RPS9,PELO,RNF208,PFDN2,HSP90AA1,SLPI,SRGN,MCM4,MCM3,ALDH1L1,USP13,CSRP1,NT5C3A,TGFB1I1,CDSN,RNF11,PSMC1,ATP6V1G1,AZGP1,HSCB,NSFL1C,SRI,BIRC2,TRIM5,TTC1,PSMA3,THOC3,WBP2,APOC2,ANXA7,PSMB7,TMUB2,LMO4,MTX2,NPY,NUF2,ATXN10,MAP1LC3A,IGBP1,TSG101,PTGDS,PSMB4,PSMB5,PPM1B,HNRNPA1,PSMD3,CDIP1,UBE2A,PSMD12,GCA,RPS27A,MCM6,TRIM26,LASP1,G3BP1,EMC8,KCTD17,OR7D4,ERP29,UBE3A,SCYL2,HSPD1,SLC25A5,HNRNPA2B1,SMIM19,CDKN2C,STX12,RNF126,AP2S1,SNRPE,RPN1,FAF2,RBM38,PARM1,MARCKSL1,B3GNT2,UBB,TXN,SLITRK1,SNX3,ARMC6,UBE2I,CCNF,UFSP1,APOC4,ENO1,F10,SMAP2,TUBA1B,AP2A1,COL1A2,ECRG4,ATP5F1A,TUFM,CTSD,TMUB1,VPS28,SS18,GTF2I,CERS2,PDHB,DESI1,VIP,PPIH,MAVS,RTN4,SQSTM1,RPA3,SPAG11B,IDH3A,FAM222B,RPLP0,UBAP1,HNRNPH3,SH3GLB2,LMNA,CDK1,TMX4,CCL3,CCNA2,RBFOX2,TXNL4A,PSMC4,UBA52,TPT1,PSMB1,SEC23A,SRPRA,SCG5,POR,PPIC,ESYT1,PSMD7,FNDC11,FBXO25,DUSP21,MDC1,EIF3E,SEM1,NOC4L,FN3KRP,SNAP23,IFNA13,FAF1,NSDHL,GLUL,C1QC,NPBWR1,RAD23B,ZFAND2A,HSPA13,GPX7,DDX39A,NECAP2,UBE2V1,TBK1,CMPK1,JPH4,CCT5 |
| 4.093e-16 | -35.43 | ATP5F1A (ATP synthase F1 subunit alpha) | protein interactions | 498 | 505 | 226 | 19454 | 5460 |
ICAM1,COP1,PSMD14,BTF3,PSMD1,COPS7A,MYC,APEX1,PSMD4,MATR3,ATP5F1B,SMU1,PAPSS2,VDAC2,EIF4B,CAV2,CNDP2,CSNK1A1,PIH1D1,MAP2K1,PPT1,YIPF5,PAFAH1B1,FBXO42,TANK,EMC1,UFL1,HNRNPA0,STAU1,RER1,ADRB2,PHB2,HSPA8,HDAC5,DDX39B,BMPR1A,POU5F1,HSPB1,YWHAB,AGR2,YWHAG,CTNNB1,DDRGK1,IFI16,WWP2,HSP90AB1,SMARCB1,RPL18,PDHA1,SOX2,ISG15,NCSTN,CHCHD2,KRAS,VDAC1,PABPC1,ATP1A1,UBE2H,RC3H2,TRIM23,PTPN11,ROMO1,IDE,KCTD9,CTSB,MRPS21,UQCRC2,RPS3,HEXIM1,UBE2M,ACACA,CYC1,RPA2,RNF146,GPR35,NDUFAB1,CFTR,HSPA5,HSPB2,PGK1,RNF113A,BAP1,USP15,NPSR1,CSNK2A1,CD81,COPS5,TSPO,USP2,COX5A,LMAN1,CAND1,CD4,SSBP1,MRPS9,SLC25A24,RNF8,TFCP2,MRPL36,NHERF1,GLRX5,UBL4A,ATP5PB,MTCH2,TP53,INSIG2,MEPCE,PSMB10,PALM2AKAP2,ATP5PF,HSP90AA1,ILK,RIT1,DCAF4,YWHAZ,MRPL16,ACO2,PMPCA,CUL3,RAB11A,MAD2L2,GNB1,DYNLL1,ACTB,B4GALT3,ACKR3,CYB5R3,SLC25A3,ATP5PO,PRDX3,COIL,ATP5IF1,ATP5F1E,CRY1,TACR1,HADHA,PSMA3,ATPAF2,ATP5MK,ATG7,HNRNPA1,CLPX,STOML2,EGLN3,OPRL1,COPS7B,GJA1,ATP6V1A,GATD3,CETN3,COPS2,WDR6,PHB1,EZH2,RPN1,NGB,JUN,CYB5R1,RAF1,FLOT1,COPS4,G3BP1,ATP5F1D,ETFA,TRIM37,OPA3,COX8A,HSPD1,TRIP4,NCKIPSD,CDC73,ATP5F1A,FBXO7,AR,NDUFB10,VIRMA,NDN,SLC25A4,PTEN,OPTN,CCNF,RARS1,COX6C,METTL14,UQCRC1,CDK7,ATG16L1,UBA52,DDAH1,POLDIP2,CERS2,PDHB,FBXW7,SYVN1,VIPR1,GPX4,SQSTM1,RPA3,NCDN,DVL2,RETREG2,CRBN,P2RY1,HDAC6,MOV10,ATP5MG,ATP5PD,CDK9,PRNP,AIFM1,EFNA3,ARL10,EEF1A1,CMPK1,FBP1,TRIM6,FBXO25,CTNNBL1,HUWE1,HAPSTR1,EMC2,HSD17B10,IGF1R,RAB1A,FAF1,SFXN1 |
| 4.130e-16 | -35.42 | RPL18 (ribosomal protein L18) | protein interactions | 6141 | 480 | 217 | 19454 | 5460 |
MRPL12,PAFAH1B1,RPL27A,PIH1D1,EIF4B,RAB5A,HSPA8,RPS28,DDX39B,STAU1,UFL1,BTF3,SFN,MYC,NSA2,COP1,RPS26,ICAM1,FTSJ3,MRPL13,RPL10,MATR3,ATP5F1B,RPS7,EEF2,DNAJC25,SOX2,RPS23,PABPC1,RPL31,CBLL1,RPL28,RPS4X,KRAS,DDRGK1,CTNNB1,XPO1,MRPL9,RIOX2,RPL6,WWP2,DRG1,MAGOH,AGR2,EED,LYAR,RPS10,FGF13,CFTR,ACACA,ZNF770,DYRK2,RPA2,RNF113A,NLE1,PML,RPL27,BAP1,HSPA5,RPS15,RPS17,RPL7A,RPF2,RRP7A,UBE2H,TRIM23,RC3H2,MECP2,PSPC1,RPS3,RPL10L,TP53,MRPL47,RPSA,UBL4A,HBP1,DNAJC2,RBM34,TFCP2,RPL3,MAP1B,SNIP1,RPL17,MEPCE,MRPS33,API5,COPS5,ENY2,USP15,RPL10A,RPS2,SNRNP70,RPL24,CD4,RPL32,MRPS9,SURF6,MYL12A,RBM42,DKC1,RPS27L,SPPL3,FZR1,DNAJC1,RPS16,CAND1,CDKN1A,H1-5,EMC9,G3BP2,ZNF668,MRPL16,CUL2,CUL3,HNF1B,RIT1,RPS5,DCAF4,BRCA1,RPS9,SEC61B,RPL37A,ZNF22,FAU,ARF1,RPL19,RPL35,RPF1,OTUD6B,B3GNT2,SART3,RPS11,CHMP4C,EZH2,RPS24,TRIP4,SLC25A5,RPS27A,TRIM37,G3BP1,MAP3K14,ATG7,MRPS35,RPL23,RPLP2,HP1BP3,RPLP1,PHB1,RPL9,FOLR1,RPL8,RPL7,CDK7,EEF1E1,RPS14,RPL26L1,RPLP0,METTL14,H2AC7,MTDH,KIN,RPA3,BRIX1,MRPL20,UTP23,RPL4,FBXW7,HMGB1,MRPL17,NPM3,NF2,PPP1CC,USP14,RPL26,ATP5F1A,DNAJC19,RPS12,RPS20,GSK3A,PRKRA,METAP2,TUBA1B,EIF4A3,EIF2AK2,CCNF,RPL22,SEC63,RPL13A,NDN,FNTB,RPL15,FCF1,MAP1LC3B,EEF1A1,SRP72,MRPL51,ILF2,TNFAIP8L1,HAPSTR1,RPL23A,PTGES3,RIGI,RPS13,MRPS18C,VRK1,HUWE1,PAK1IP1,HDAC6,GRSF1,ACTA2,RCHY1,RPL12,MRPL24,CDK9,MDM2,DCUN1D1,RPL35A |
| 4.416e-16 | -35.36 | ACTB (actin beta) | protein interactions | 60 | 958 | 382 | 19454 | 5460 |
H1-1,ATG3,PSMD14,S100A11,CCT2,CKB,BAG3,BTF3,HNRNPC,HNRNPAB,MYC,CREBBP,NCKAP1,APEX1,ESR2,CBX5,SSH3,TAGLN2,VDAC2,CSNK1A1,PPT1,MTMR6,EFHD1,TOMM22,LYG2,PHB2,DGCR6L,UFL1,DR1,MAGOH,CBL,MGMT,GSTO1,CTNNB1,IFI16,CCT7,HSP90AB1,PEG10,SUMO2,HNRNPL,SWAP70,SMARCB1,PDHA1,PTRH2,PLS3,RAB8B,PFDN1,ROCK2,RUVBL1,PSMA1,HNRNPF,TRIM21,MYO1B,UBE2H,PDCD4,RIC3,CFL1,ARHGAP21,CFL2,RAB2A,AKT1,IFI6,CSNK2B,GNAO1,UQCRC2,CYC1,LEMD3,FGFR1,IGFBP3,CD2AP,AIF1L,ARFIP1,PGK1,BAP1,MAP4,NUS1,SHC1,TPM3,GAPDH,API5,CD81,PCYT1B,COX5A,DPP4,MYL12A,PLG,CAND1,CPNE1,RAC2,ADD1,DSTN,NUPR1,CAPZA2,TMSB10,TP53,PSMB10,MEPCE,HNRNPK,NEDD8,DHX9,PSME1,MAP1B,CCDC25,PFDN4,SMARCE1,HSD17B3,RAB11A,CLIC4,TAF11,UBE2V2,ACTB,RPS9,SNRPD1,VPS72,PNMA1,ANXA7,SLC25A3,PRSS23,CDKN1A,DAAM1,RRAGA,ACTL6A,FBXO30,PSMA3,COTL1,VCPIP1,HNRNPD,HNRNPA1,BCL7C,OPRL1,WDR44,PPIA,USP46,ATP6V1A,KLHL7,GDI2,ACTN4,ANP32A,TNF,HNRNPA2B1,ZYX,VIRMA,CTTNBP2NL,SH3BGRL,NREP,NDN,TMOD3,MSN,CTTN,CTNNA1,CCNF,WTAP,METTL14,DCTN4,UQCRC1,CHMP2B,PIK3R2,TTR,PDHB,SOD1,RPA3,CNN3,UPK1A,PROM1,ATP5MG,H2AC14,CDK9,TMCC2,MDM2,RPL35A,TES,ACTA2,EFNA3,SMAD3,PTPN1,ACTR2,NDUFS3,CCT5,FBP1,RIGI,ADD2,SMN1,CPNE2,MRFAP1,SFXN1,PPP1R12A,RAB1A,LTA,FAF1,POLR1B,ICAM1,LRRC20,EPS8,TBCE,PPP5C,PSMD6,ATP5F1B,PIH1D1,ELK4,TSHR,EHHADH,PAFAH1B1,SAP18,STAU1,EP300,HSPA8,YWHAB,SMAD9,AGR2,SYNJ2BP,TCP1,CORO1C,ZRANB2,MTA2,RAB4A,ISG15,ERRFI1,IFNG,VDAC1,KRAS,ICAM3,RUVBL2,TOP2B,CCT8,PABPC1,CTTNBP2,MORF4L1,NAA50,BCCIP,SRPK2,NMI,SMURF1,SGTA,RPS3,STAT6,PRKCA,UBE2M,HEXIM1,RPA2,CFTR,NDUFAB1,SPTBN1,HSPA5,LCP1,HSPB2,TMOD2,RPL10A,AQP2,USP15,FAM187B,TPGS2,TUBG1,COPS5,DNAJB2,CDC5L,TMPO,COX4I1,SYNCRIP,RNF8,NFE2L2,ARPC3,TFCP2,ARHGAP12,H2AX,RPAP2,ACTR1A,MTCH2,UBL4A,DUSP19,CAPZA1,SLC25A11,PALM2AKAP2,PFDN6,RIT1,FAM107A,LMNB1,SAMHD1,CUL2,CUL3,RRN3,VEZT,DYNLL1,RBBP4,MB21D2,AP2M1,CYB5R3,RNF7,ATP5PO,PRDX3,PPP1CB,MTX2,TASL,NCALD,SKP1,WASF3,FBXL4,PTN,NPB,HADHA,NMRAL1,BCL2L1,RASSF8,PSMD10,STOML2,PSMD3,PRDX1,NDUFS8,KCTD10,TRIM15,SPTAN1,SLC6A2,OCIAD2,PHB1,FOLR1,EZH2,LGR4,CYB5R1,CCS,MARCKSL1,TRIM37,G3BP1,LASP1,TRIM26,FHL3,UBE3A,INO80C,BLOC1S2,ATF3,MT3,NAPA,TADA3,CCDC22,IVNS1ABP,NONO,AR,PPP1CC,USP14,NTAQ1,ATP5F1A,RUNX1,NDUFB10,CAP2,DUSP10,HOMER1,TECR,SLC25A4,UBASH3B,UBE2I,EIF4A3,TMSB4X,STUB1,TMOD1,RPLP0,PDIA2,LSM2,ZMYM6,LMNA,MX1,SIPA1L1,FABP4,MBD3,TPST1,SGF29,SQSTM1,ARPC2,FGR,HDAC6,TLE1,CAV1,ATP5PD,PPP1R18,AIFM1,ILF2,SLC25A20,DMAP1,RPL15,EEF1A1,DDX39A,FBXO25,CTNND1,WASL,TFPT |
| 4.467e-16 | -35.34 | KIF23 (kinesin family member 23) | protein interactions | 9493 | 1003 | 397 | 19454 | 5460 |
PTGES3,SMN1,ADD2,HUWE1,FN3KRP,FARSA,RPL23A,PPP1R12A,RAB1A,NKRF,NDUFS3,APOBEC3D,ACCS,TOMM70,CDK9,RPL35A,RPL12,KRR1,LRRC8B,TRPC1,POR,ZNF200,MOV10,BRIX1,PDHB,FBXW7,CLK1,TCEA1,RPA3,RPL26L1,HNRNPH3,GNAI2,VIRMA,COPE,TMOD3,TRIM27,NEGR1,RPS12,ALB,CCNF,ENO1,AP2A1,MAPRE1,PPIG,RPL26,RACGAP1,UBE2A,PSMD12,FLOT1,SSRP1,DHX16,ASF1A,SRSF7,BAG2,HSPD1,HNRNPA2B1,RPS11,SNRPE,RPN1,CHMP4C,RPL29,FAF2,SRSF10,PPIA,DHX15,NDNF,RPLP2,RPL9,RPL8,MRTO4,WDR12,DROSHA,HNRNPA1,PDIA3,PIK3R1,SLC32A1,ERH,USP5,MRPL23,EIF4A2,SNRPD2,RPS9,GNG12,RPS5,VMP1,ILK,YWHAZ,BRCA1,RPS29,PYCR1,MEPCE,RPL17,H3C1,HNRNPK,DHX9,ZNF451,BIRC5,GNAI3,NUPR1,SURF4,CBX3,CAPZA2,IMP3,STRBP,RPS27L,PHETA2,ACSL4,ALYREF,RPL32,AKAP8L,RPL24,GAPDH,BNIP3L,RPS15,WDR3,DLAT,RPL27,LUC7L3,CD2AP,DYRK1A,RPGRIP1L,TXNDC12,MACROH2A1,SF3B6,ABCG2,IGF2BP1,CFL1,ARHGAP21,CFL2,SMARCA5,TRIM32,RPL7A,CCAR1,RPS4X,PSMA1,HNRNPF,RUVBL1,MYO1B,GNA11,RPL31,ABCF1,RPS23,H2BC1,RPS7,EEF2,ETFB,DHX38,HSP90AB1,RPS10,HNRNPL,SNRPD3,SUMO2,PABPC1L,TNNC2,DDX1,YWHAG,XPO1,YWHAH,NGDN,CTNNB1,QPCTL,DDX50,IFI16,RPL6,PACSIN3,FXR2,SRSF2,TRA2B,PHB2,EEF1G,SF3B1,DDX5,NANP,RPS28,NUFIP2,CSNK1A1,APEX1,ESR2,RPL10,TAMM41,MATR3,TAX1BP1,RRAS2,VDAC2,RPS26,CDKL2,PSMD1,SNRPB,RALGAPA2,BAG3,MYC,HNRNPC,SFN,HNRNPAB,RPS13,ARF4,EIF3E,MSH6,CAMK2G,THRAP3,RING1,HSD17B10,ILF2,SRP72,RPL15,AKAP17A,ARF6,TOP1,FAM149B1,SEC23A,PWP2,H2AZ1,ESYT1,MPHOSPH10,HDAC6,POLDIP2,AATF,EIF5B,USP8,RPL4,SQSTM1,GPX4,MME,CSTB,SIRT7,OXSR1,RPLP0,MACROH2A2,LMNA,JUP,HSP90B1,RPS14,MYL12B,RPL22,MAGOHB,YES1,RPL13A,RTRAF,CHCHD6,RPS20,PELP1,OPTN,EIF4A3,STK11,STK24,ATP5F1A,NONO,PPP1CC,TUFM,PYCR2,G3BP1,TRIM37,ETFA,SLC39A7,SRSF8,RPS24,ARGLU1,NDUFA4,OXNAD1,ASPM,GFPT1,NOP58,KCTD10,RPL7,SPTAN1,RPLP1,FOLR1,THOC2,RPL23,DDX23,FIG4,ATG7,WDR11,TRA2A,CLPX,PRDX1,MRPS35,STOML2,RAB3D,PSMC1,COIL,SKP1,G3BP2,VLDLR,HADHA,NUBP2,MYL6,APOBEC3C,PPP1CB,RAB6A,H1-5,CHCHD3,GNB1,RPL19,RPL35,DYNLL1,LRRC1,CPSF1,RAN,RIT1,RFC5,MCM3,CLBA1,NOP16,SRSF12,SRPRB,TOLLIP,KPNA2,RPL3,PSMC3,RBM34,H2AX,TMPO,DKC1,RPS16,SYNCRIP,COMT,RPS2,RPL10A,SNRNP70,CSNK2A1,RBM17,HSPA5,MARS1,HNRNPH2,RAB9A,PRDX6,BANF1,ARHGEF6,UTP15,SCLT1,H2BC11,RPA2,CSNK1A1L,ZNF326,IDH2,SAMM50,NDUFAB1,SPTBN1,MRPS21,BUB3,RPL10L,EIF2S2,RPS3,LIG3,ELAVL2,CALU,RAP2C,DNAJC10,RPS17,UTS2,RNASET2,RPF2,GSTK1,RPL28,HNRNPDL,KRAS,H1-6,PDIA6,RTCB,PABPC1,TOP2B,ZRANB2,RPL18,CRKL,SMNDC1,SOX2,TNPO2,TOP3B,MEAF6,LYAR,MAGED2,RFX5,CORO1C,SRSF1,SMAD9,YWHAB,DRG1,HSPB1,PPIB,GSTM3,SAP18,STAU1,HSPA8,STK26,RAB5A,RFC4,XRCC5,CD59,RALYL,RPL27A,DES,ATP5F1B,FAM83B,SF3B4,BST2,FTSJ3 |
| 4.595e-16 | -35.32 | protein metabolic process | biological process | GO:0019538 | 3496 | 1228 | 18204 | 5365 |
SIAH2,DYRK1B,AKT1,BMP1,HERC4,PPP3CA,KBTBD2,EIF4B,FKRP,ADAM21,GPC1,CCT7,PDRG1,DNAJC24,RPL26,UBA52,RPS4X,DUSP26,SIRT7,PSMD6,SKIC8,PSMA4,CALR,NSG1,FBXO9,CHCHD1,PSMA5,FEM1C,PPP1R11,MRPL23,UBE2W,CLK4,APH1A,IGF1,B4GAT1,GID8,BAK1,NUDCD3,TNFAIP3,KIT,SPSB1,TOLLIP,PFDN4,CPE,EIF4A2,DOLK,COQ8A,XBP1,TSPAN5,RPL13A,RPL27,UBE2D1,MRPL52,TGFBR2,TRIM63,PAK2,CYTL1,PAIP2,PCSK9,MATCAP1,USP46,B4GALT1,TSG101,PPP5C,RPL4,E4F1,PPP3R2,PARL,DIO2,RGMA,DOHH,GLCE,SCPEP1,PSMA3,FN3KRP,EGLN2,PRKCE,SYVN1,SPRR1B,B3GALT2,CDK5RAP3,FUT1,DHPS,AKT3,UHMK1,COPS2,HECTD3,RPLP2,PPP1R12A,PPP2CB,AKT2,PSMA6,HS3ST5,DAPK3,KLHL25,CLIP3,RNF181,RPL12,OXSR1,ERLIN2,ZDHHC14,MMP14,UBE2K,ACVR1C,DCAF4,MAGEC2,IMMP2L,CHMP1A,PSMB7,PAIP1,MMP9,TOM1L1,LAMP2,NDST1,EIF4E,HEXA,TRAF3IP2,USP38,GP9,RPL10,METTL18,PPP2R5A,ZBTB16,PSMB11,UBA3,HDAC3,ADM2,ATG7,B3GALT4,DNAJC3,ST3GAL2,MMP20,SRD5A3,UBE2S,B3GALNT1,TNIK,PSMB2,JKAMP,DNAJB2,DNAJB6,AQP11,RIMKLB,PREP,HM13,NMI,RPL27A,PAX6,UQCRC2,PSMB6,GFPT1,URM1,CASP12,TUFM,PRKAG1,NUS1,TP53INP2,MED27,SLC35C1,TAPBP,CHMP2B,OTUD6B,PIGW,VPS18,ASRGL1,RPL7A,DUSP21,ARFGEF1,DERL2,ACVR1B,MED10,SCG5,BFAR,PPME1,NLRP1,SYK,PSMC1,SELENOT,LAP3,TRIM5,PPIC,ALKBH4,STK11,TMCC2,HDAC6,ZDHHC17,MRPL17,S100A8,DPM2,TESC,NME2,FBXW7,PARP2,WEE2,PRSS8,KCTD10,VSIR,APEH,UBAP1,DCUN1D5,EGLN3,LACRT,PSMC4,DUSP1,BIRC2,YES1,KBTBD6,ASB1,PRKAB1,GLUL,MRPS18C,RLIG1,UBE2L3,TRMT112,TRIM32,FKBP4,TBCEL,ST8SIA5,DPEP3,USE1,MRPS25,RPS13,MYLIP,TLR2,DUSP9,MRPL13,DMPK,MRPL12,PPM1M,MRPS9,PPIF,CDK4,RNF26,TBK1,PIAS1,CSNK1A1L,RNF10,PICK1,DPP4,YIPF5,RMND5B,DNAJC1,EIF5B,MAPKAPK5,CCL2,GLRX5,PSMC5,DUSP6,MGAT5B,RPL10A,NPPC,PIGA,CHRM3,DCUN1D3,EXTL2,TRIM35,G2E3,TOR2A,ASB11,ADPRH,PARP11,RNF41,UTP25,ANKIB1,BACE1,RPL35A,CHST13,DPH6,ZC4H2,MAP3K21,CDC23,SPOPL,F7,FBXL3,ZFAND2B,RPS10,CDSN,CAMP,ADRM1,LYPLA2,OARD1,RHBDL3,ROCK1,GFM2,CACUL1,YWHAZ,PGA4,RNF148,PRKACB,PSMD1,CDK17,VKORC1L1,ST3GAL5,CUL3,SETD4,KLF1,TRIM10,CDCA3,ZNRF1,CCDC47,STT3A,CAMK1,MRPL49,CAPN2,PIGY,AREL1,ASB8,HS2ST1,TCP1,RCE1,PPM1B,GTPBP2,EIF3E,PPM1G,MRPL41,IL15,RPS11,NSMCE3,RPS12,UNC45A,HSPB6,PRRT1,METTL21A,CCAR1,PPM1K,RNF115,CTSA,VRK1,CLK1,RPL31,FAM20C,FEM1B,SDF2L1,SEPHS1,COL3A1,FKBP2,MSL2,MARCHF9,PRSS1,RNF167,CFAP20,FAM8A1,ISG15,RNF8,GALNT4,ST6GALNAC3,KLHL15,RLIM,ZFAND2A,NEDD8,DUSP3,GTF2B,UCHL3,TPSG1,GFM1,CHST9,DPEP1,TMUB2,TRIM8,LORICRIN,OTUD7B,PGAP2,EIF2B3,GZMK,LTO1,RPL29,RNF11,AANAT,ALG11,NDFIP1,CBL,MRPS17,PCMTD1,ERO1A,OLR1,PPIG,BAG3,PDF,CPEB1,CSNK2A1,RPL7,HCST,PTPN5,IL1R2,DLG1,CHST11,DNAJC25,UBXN10,DCAF5,MTRF1,DNAJB9,PSMB1,GXYLT1,TOPORS,TNNI3K,PELO,ING5,PRPF19,OS9,ANAPC11,KDM1A,PPTC7,CTSB,OTULINL,EIF4EBP2,RIMKLA,ZBED1,FKBP1A,CTTNBP2NL,TLR7,XXYLT1,VIPAS39,CTU1,SNRK,CCS,HGS,PRMT2,PPP1CC,MAP2K1,HSPA14,DRG1,SLC6A7,PMM2,PCSK2,HERC3,EIF5A2,SHPRH,REN,FBXO8,STK3,RNF34,SETD7,UST,MAP3K12,ETFBKMT,DYRK2,CDC16,EPHA4,TLR3,TRIM68,RPS14,TUSC3,ZDHHC15,SOCS2,CRYAB,PGAP3,SECISBP2L,PPIA,ABHD10,FZR1,IGF1R,CSNK1E,FBXO32,PPP2R5E,IFT172,MTMR6,RCHY1,TRIM54,IL4,CDC37L1,NTMT1,HSPA5,SOCS5,SPOP,PSMB10,HTRA2,KLHL3,RPL37A,RPL10L,PDP2,MRPL57,IGFBP3,FAM98A,FXN,CSNK1G3,RPL17,RPL18,FURIN,F9,ALG5,CYP3A43,EEF1E1,USP5,RUVBL2,FBXO25,STAMBPL1,ANAPC15,YAE1,MRPS16,CMA1,RNF7,RPS9,CDK5,BCKDK,RPL28,NSFL1C,PFDN5,RSL24D1,SH3BGRL,KLHL9,STUB1,DNAJC10,PSMD3,DUSP10,CSKMT,PLG,CCT8,RNF5,HECW1,MRPL34,MED11,KDM2A,EPHB6,PPT1,MUL1,DUSP18,TMUB1,GRPEL2,ERLEC1,PSMA2,PDIA3,CDK8,KCTD9,BOLA3,NLRP3,CNDP2,GALNT12,PPM1D,RP2,RNF133,OTUD6A,MAPKAPK3,CSNK2B,CHST7,CTSD,GGCX,FUT8,ABCF1,LCN1,CDK9,TOP1,RNF141,TNFAIP1,RNF152,ILK,CASP4,RPL6,HSPA8,PPIB,BAG2,LARGE1,PTPN1,TRIP4,RPL9,CHORDC1,MRPS11,RPS15,TLR4,RARS1,TSSK1B,TMEM165,FBXO30,TOR1B,CRBN,B3GALT1,ST3GAL4,CLCA1,SPCS3,ST6GAL1,SUMO3,CIAO1,STK4,VCPIP1,PSMB5,MDM2,PIGC,AGA,CDC26,FTSJ1,RPL35,CSGALNACT1,ANAPC16,NCBP2,NEK7,PTAR1,FBXL14,MAP3K3,CHMP5,MRPL10,CAMKV,PPP2R1A,B4GALT3,NAA35,PCMTD2,ASB7,TRIM52,KLHL22,PPWD1,ALG2,BPNT2,NQO1,PPP2R3A,F10,GMPPB,SGTA,RPL15,CHMP4C,UFL1,TRIM44,SIAH1,TRIM15,PTPN4,RBCK1,HINT1,METAP2,HMCES,RNF139,CDC123,DET1,HEXB,EIF2B2,ATAT1,B2M,FAF1,RPS26,GPHN,PSMB9,MRPS35,DCAF16,UBE2G2,UBE2V2,CDC7,DPH3,UBE2V1,SELENOS,SDHAF2,UBXN6,MRPS34,ASB3,DDI1,RPS27A,RNF128,MAPK4,PDIA2,PRMT5,KARS1,NPC1L1,ARMC8,PRKD3,RPN1,WDR77,PSMD12,NAA16,EIF3D,TTL,EP300,RNF103,SNX5,RPSA,CYFIP2,NTAQ1,TMEM106A,RNF208,COPS7B,KLK5,CTSK,CRTAP,CTNNB1,MRPS18B,SEC61B,PSMB3,EIF2AK2,HTRA1,RIOK2,DESI2,WDSUB1,ATG4C,MARCHF4,RIC3,TRIM24,UBE2N,STK26,PLAA,PSMC3,SKP1,UBE2M,CDK12,NUP153,CTDSP1,TSPAN15,GALNT17,CAND1,USP3,PTEN,JAK2,FBXL19,CDKL2,CHPF,MED31,ACACA,ABCE1,B4GALT7,DERL1,UGCG,BAD,GSK3A,EIF3G,PSMD7,MRPS7,AURKAIP1,LDLR,HSPD1,TRIM34,RNF122,PAK5,RPL39,TRAF7,ST13,PPARA,PELI1,NEUROD2,EEF1A1,MRPL11,ADGB,GNMT,WSB1,GAL3ST4,UBE3A,DPP10,RNF14,FGR,UBE2E2,RPS17,RNASEL,BRAP,DUOXA2,STOML2,NIM1K,ASMT,UBB,CSK,PI3,KBTBD13,STAMBP,USP2,COPS7A,ERP29,RHOBTB3,JAK1,UBE2B,MAEA,SMURF1,RWDD1,EEF1G,RPS2,MRPL22,ECRG4,INHA,ANAPC2,CPNE1,KLHL24,DPH5,ENPEP,NEURL2,EIF4E3,RPS23,IFI27,HSPA13,CHMP2A,RPLP1,RMND1,RPLP0,HYPK,GANAB,CD36,RPL26L1,PMAIP1,SNAPIN,BAP1,RPL3,MED30,OTULIN,ANAPC13,CISH,UBL4A,RPL19,ZDHHC4,CLU,FNTB,PSMA1,STK38,GRPEL1,DNAJC4,RPS7,GPAA1,DUSP22,EIF1AX,ATG16L1,ATG4A,NT5C2,SELENOK,ELOC,IRF2BP1,TRIM62,NAE1,DNLZ,FKTN,NDP,NLGN2,TRAF6,UBLCP1,NAA11,CSGALNACT2,CCNF,ZDHHC16,MRPL24,TPST1,FAM20B,DNAJC7,THBD,TTC1,CD2AP,NEK2,RNF40,TMEM59,TRIB1,MRPL18,PML,RPL32,PRSS12,DISC1,FBXW4,IRF2BPL,BMPR1B,CLPX,PRSS37,MGAT4A,MRPL20,P3H1,LIPT2,UBXN2B,MRPL33,SPATA2,HS3ST1,FUT9,RPL24,B3GNT2,EIF2S1,PSMB4,SERPINH1,PPID,SUMO2,EIF1B,SRC,PPIL3,CDK20,MSRB3,DAG1,MTMR2,SRGN,MMP28,XPNPEP1,PTGES3,GXYLT2,EXT1,LEP,RAB40AL,SQSTM1,MGAT4B,SNRPB,TRIM21,CHPF2,MRPL51,ISCA2,PSEN2,CBLL1,RNF121,GALNT1,MED17,FAU,DTL,RNF146,RPL8,MACROD1,BIRC5,METTL22,SENP5,USP30,MRPL53,TESK2,TRIM45,STK16,TMEM208,MAN1A2,PIGK,C1GALT1C1,SLC30A5,TRIM3,DNAJC5,STYK1,EIF2B5,NBN,FBXO44,EIF3K,MGAT1,HS3ST3A1,EIF1AD,CCT5,NTRK2,RPS24,IFI16,PGK1,B4GALT4,GOLGA7,UBL5,BMPR1A,NFE2L2,DNAJB4,FBXO7,GCNT3,PRMT6,LYPLA1,SPSB3,UBASH3B,BNIP3L,PDIA6,MRPL50,TMEM199,BMPR2,TTC4,DYRK1A,EIF2D,PXYLP1,EIF3J,GAL3ST1,PTPN22,PRSS23,USP13,TRIM37,ZDHHC24,CREBBP,UBE2F,RPL22,MPDU1,MARCHF3,KLK3,VPS4B,FARSA,QPCTL,ADAMTS10,MRPL40,METAP1,PAK6,FCN2,KLHL12,SNRPD3,RNF39,DCAF11,SRPK2,DRG2,ADAMTS1,FBXL4,RING1,BAZ1B,AIP,MRPL9,PRCP,TRIM22,HSPE1,ADAMTS20,MRPL36,CISD1,P4HA2,CDK7,CSTA,USP14,EDEM1,PGPEP1,CCT2,PFDN2,SETD3,RNF126,SUMO1,COPS5,EEF2KMT,PRKCB,CTBP1,FOSL2,AHSA1,RPS6KA4,MARCHF5,CDK1,PELI3,ATP6AP2,OST4,UBE2A,DAD1,WDR45,CTDSP2,NAA50,CDK5R1,HSP90AA1,MED21,USP15,EIF2S2,SOCS4,PREPL,WWP2,PMPCA,MRPS26,MRPL16,KLHL7,SPON1,MRPS28,DNAJC19,MARS1,HSPB1,PRDX3,SLC35A1,CDC20,FAF2,DAPK1,HSPB2,ACTMAP,CREB1,ANAPC4,ZER1,SELENOF,FBXO11,RPL23A,COPS4,BRCA1,WWP1,ZMPSTE24,IFIH1,RPS27L,MRPS21,PSEN1,TNKS2,EGR2,MTM1,TRIM26,PLPP6,RNF113A,IDE,UBE2I,MRPS23,VCPKMT,SELENOO,RC3H2,MTG1,USP8,TAB1,TNKS,MRPS33,NDST3,PFDN6,TRIM11,SOCS3,PRDX4,COQ8B,PPP1CB,ACHE,CELA3B,LYPLAL1,MSRB1,KCTD17,ST3GAL1,PTPRZ1,CBFB,HSP90AB1,NAA60,ERLIN1,FKBP1B,PIM2,H2BC1,RAB6A,STX1A,VPS28,KLK6,MINDY3,MBL2,ABHD17A,ZDHHC8,DFFA,KLK9,MME,KCTD11,FEM1A,PSMD4,RPS29,MAPK10,DPAGT1,CARS1,GTPBP1,CAB39,RNF182,ROCK2,RAF1,GID4,ZC3H15,MMP21,NAA15,APPBP2,GALNT2,DDRGK1,MAP3K11,SENP8,TRIM6,TMEM106B,RPS3,EEF2,PRKX,ETF1,TRAF2,FBXO31,TRAF1,RAD23B,ACVR1,STK38L,EIF4E2,RPS16,AIPL1,DDR1,GANC,RNF144B,WDR83OS,LMAN1,MTRES1,PRKCA,FBXO3,CAPN1,UFM1,PSMD14,RPS28,F2,EDEM2,BOLA2B,PPIH,POMT2,RABGGTB,ATG3,USP16,HSP90B1,EEF1B2,PGGT1B,UBE2E3,DCUN1D1,STRADB,TRIM23,QRSL1,SPCS1,FBXW11,RAG1,CHMP1B,PSENEN,NDUFAB1,PTPRQ,TBCE,TTLL10,VASH1,FGFR1,MRPS18A,DDIT3,FKBP10,TRIM27,CTRB2,SEC11A,FBXL7,UGDH,CDK6,DNAJC2,PTPN11,HUWE1,CCL11,ENC1,SPPL3,CTSC,FKBP8,SVBP,LCMT1,GNPTG,PFDN1,CHST10,UBE2D3,PGAP4,VPS4A,IL21,EEF1AKMT3,ZNF451,GOLGA7B,RNF187,PRKCQ,SPCS2,STK24,COP1,UFD1,HECTD1,UBR7,RNF20,B4GALT6,JOSD1,RPL23,CCNA2,CSNK1A1,LIPA,ST8SIA4,DESI1,MKKS,IKBKB,MYRF,CHCHD4,GAPDH,UBE2H,EPO,CUL2,CLN8,PCYOX1L,MRPL47,EZH2,AASDHPPT,ITK,RPS5,FBXO22,CEP41,EIF4H,NCSTN,RPS20,EDEM3 |
| 4.956e-16 | -35.24 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 15350 | 4540 | 16828 | 4835 |
E2F6,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,MRPL23,GDI2,GFM2,KLHDC8B,RNF141,ARHGAP1,DOK4,KLK9,PLA2G5,PDIA6,UBR7,SDR42E1,PRIM2,SNRNP27,CD99L2,TRIM32,SLC17A5,SLC25A31,ZNF671,UGCG,MEAF6,LYPLA1,LIG3,RPS14,TMEM219,ATP6V0B,EDF1,ZNF207,POLR3H,TMUB1,C1QC,TRIM3,FIBIN,WDR38,SNX20,L1CAM,TLR9,COMTD1,FNDC8,FGD2,APEH,AKT1,DLX1,DPP10,PRRC2A,CRABP2,DKK3,IL20RB,SF3B4,ASMT,CCNI,RAB11A,PPIL4,CDO1,LYAR,TOM1L2,GNRHR2,UST,EXOC8,PFDN5,RND3,CNP,NUDT3,B9D1,GSTO1,TMEM156,SOCS5,AK2,GALNT1,CCDC69,PSMA3,MRPL13,MDM2,MGP,EHBP1,SLC38A9,IL15RA,RMND1,PPP1R2,FAM78A,MIOS,ENY2,RAG1,MEF2A,IMMP2L,SLC35A1,DHRS4,MRPL24,MRPL50,ZNF304,SNAPIN,KLK3,SLC30A5,MYL12A,CYP39A1,HSD11B1,SWAP70,LRRC69,FAM8A1,NCR3,EIF4H,ITK,CHDH,GNRH2,SENP5,IDH3B,GRM2,CTNNBL1,CYP11B1,TLR3,ADGB,JAKMIP1,GPAA1,ZMYND19,SLAMF9,TAAR1,CCR6,ZNF319,SEC14L1,ID4,ZNF397,APOBEC3A,XAGE5,GLUL,CNIH4,NRP1,NCKAP1,CDK5R1,CLU,ATPAF2,KIAA0232,LMO4,LTBR,GAL3ST1,CASK,FGFR1OP2,GABARAP,PRPSAP1,ELMO1,GRPEL1,TCP11L2,UBE2D3,ATP6V0E1,CCT2,UBE2A,ARMCX1,ING1,STRBP,IRF1,NAIF1,TRIM23,NHP2,MYH2,SNAP91,SLC7A9,PACSIN3,ALKBH4,HEBP1,PGK1,ROPN1B,VRK1,TMIGD1,DNAJC5,DYNC1I2,S100A6,CYP27A1,CDC73,ZYX,UBAP1,LHX2,MMP9,BTF3,P4HA2,JOSD1,SUPT7L,RS1,KIT,LSM3,AFTPH,RARRES2,CSNK2A1,PIWIL4,KPNA1,KBTBD2,GSTO2,GNG7,CTNNBIP1,ATF4,NDST1,DEFB116,TNFAIP8L2,DHRS3,CDCA3,RAB3B,SMAP2,KTI12,FGF1,INO80C,AZGP1,ABCB1,HBE1,PSME2,AZIN1,TBC1D10C,MAGOH,NKX3-2,CCL19,MLF1,GTF2E2,LBH,JAK1,FBXO42,TMEM215,ZNF24,SERPINB10,TSEN54,MEST,FZD4,WDR77,MTPN,ATP6V1G1,LYG2,MFSD6L,ZCCHC10,SYN3,GPBP1L1,MX2,AAMP,FAM199X,CLDN11,NIPA2,RABL2B,TRAPPC1,SPTAN1,SLC35E3,RNASET2,LRP12,NPY2R,ADRB1,PKNOX1,ZDHHC14,RFX4,FRMD8,HEY2,RBM17,PCDHB8,TRIM21,SIX5,ACTA2,ARMCX2,SPR,GALNT12,ARFIP1,PPARG,NFIL3,HECW1,TRIM37,ZBTB38,PTPN1,HNRNPC,SETD5,RMND5B,SLC25A21,RBBP7,PGS1,ZNF593,ARMCX5,PRPF4,IMPACT,AGER,CD58,IDH2,FKBP14,RAB18,ENPP4,CCT5,PSMB5,MCOLN1,SBK2,SORD,ANAPC2,FBXO32,AGK,HCRT,CAMK2N1,FGFR1,PYGM,SHC1,FAM89B,PEX3,RCVRN,CCDC127,CD200R1,PPP3CA,CRYGB,KCNJ11,PRMT2,CIB3,TACR3,BUD31,TMX4,SRP54,CAMK2G,CCDC47,SCFD1,TTC4,GHITM,TUBG1,RPL15,CACNB4,ZSCAN1,EIF4EBP3,WDR37,IL23A,PSMD6,FURIN,DHX9,SLC39A9,AQP4,CREBL2,TXNIP,CCL25,GNMT,GLE1,UTS2R,NEK7,SPOCK1,PHKG1,LASP1,FUT8,WBP2,GTF2A1,EIF2B5,SH3GLB2,GALE,CXXC5,ENDOD1,ANKIB1,CIRBP,APOBEC3C,GPR162,RNF187,TXNRD3,ZMYND11,SLC7A4,ZNF513,EEF2,THRAP3,SLC25A32,EFHC1,GJA10,EXOC2,XPO1,XPO5,SURF4,INTS10,TF,CREB3,RNF103,RANGRF,NUDT19,THOC1,ABCC5,DNAL4,ATP2C1,FATE1,RC3H2,NUBP2,PFDN6,LDHA,UBXN10,SLC20A2,PCDHA5,GSK3A,PRCC,ST13,RASGRP2,LPXN,IL34,DFFA,RAP1A,UCKL1,ACAA2,RABAC1,WWP2,TIGD7,FBXO30,POLR2I,CD2,TRMT6,PTCRA,CXCR1,NEDD8,FGF17,HBB,KCND2,CCL21,NDUFA5,RBM23,TMED1,HEXA,ADAT1,OCEL1,BRI3,CDKL2,CHRNA7,GAS8,KIF1C,CD3G,BRMS1,NQO1,IPP,SPATA2L,TBCE,TAC1,OPA3,AKR1C2,LMBR1L,NPVF,IGFBP4,HADHA,LEAP2,DHX16,TRA2B,SOX21,RAB4A,NUDT16,OR6M1,GXYLT1,KCNA2,HSPB1,B4GALT6,LHFPL1,HSPE1,CLDN14,ZKSCAN1,STAMBPL1,SIPA1L1,PGBD2,SERPINH1,RPL37A,RPRML,MSX2,SNAI3,PELI3,CDC37L1,KRR1,NLE1,NAA11,EIF1AD,APH1A,NDUFB8,ISYNA1,XPOT,PDIA3,FRA10AC1,WNT7A,STX17,LEPR,SFTPD,CLEC12B,RAB8B,CTNNB1,CYP2D6,INTS12,SOCS2,ESR2,DCAF5,CWF19L1,CDK6,ADCY3,SNRPD2,FAM13B,SLPI,CERK,USP39,ZNF174,USP38,SYNGR1,LSM6,RTP4,ZMAT5,FGF13,PRKX,PROX1,VPS4A,ENPEP,NAB1,TCP11L1,SOST,HPCA,SV2B,OR2A2,EIF4EBP2,EMC4,SIVA1,GFOD1,SNAPC1,SNTA1,GPR37L1,NDUFAF2,SPRED1,H19,MAK16,ALDH1L1,TSSC4,POLL,NONO,SIRT7,FYTTD1,IQSEC1,NOL4,TAPBPL,RRAGA,ETV6,RAP2B,ABHD16B,TNFAIP3,TRAF7,MMACHC,DUOXA2,MTMR12,NOP58,SPATS2L,AKR1A1,NFE2L1,RBCK1,MRPS25,PGAP2,CTSD,FABP5,MRGPRX4,SCAMP2,NUP107,SPEF1,CYP4F8,PRKD3,SLC5A6,DEK,NLGN2,PPIB,CDKN3,BPGM,CD164,NPTN,FCAR,CCDC42,CYC1,POU1F1,ID1,PTDSS1,ENTPD4,ARMC8,SLC35A2,DEGS1,CRYBA2,INPPL1,KIF2A,MIA2,BACH1,AP3S2,MPHOSPH10,MRPL47,TMEM33,S100PBP,KLF10,FAF2,BMPR1A,SPINK13,RHCG,ARHGAP21,SCG2,LCN6,SETD4,CCND1,RPGRIP1L,OR2W1,TMED3,ACOT13,WFDC13,COX7A1,FBXO9,ANP32B,CHST9,CPT2,AP1G2,NDNF,PWP2,MTAP,RAB3C,CACYBP,CTSK,CETN3,URM1,NFYA,FAM200A,S100A10,STX8,BATF,TOLLIP,DUSP1,TGFB1I1,CRYBB3,FOXS1,PTRH2,TAS2R5,TMEM203,ACTR2,ACP6,SYNJ2BP,TMEM164,TMCC2,SELENOS,ZNF609,SLCO1A2,KCNK10,SRP14,NUS1,TMEM106C,KRT7,PLEKHA8,WDR3,GJB2,MANSC1,ISCA2,UPF3B,RABL3,ZNF576,GCA,PPP1CB,TRAM2,CHST1,FCHO2,MPV17,EHD1,RFXANK,TRAM1L1,SESN2,PLAGL1,KLHL15,CLDN8,ADAMTS1,CXCL14,TUSC3,RPL6,BNIP3L,DDX42,SLC7A14,GMPPA,CYB561D2,MT2A,PPP1R16A,ATP1A2,PXMP2,HSPA14,CXCR4,NPY5R,POLR3B,PGR,HAND2,BRD9,KCNH1,KIAA1191,CCL17,OR2H2,DLG4,GTF2F2,BICD2,SERPINA5,CREB1,RNF122,KIAA0408,RBM12,RPP25,RAN,SQSTM1,GLIPR1,FMO2,TMEM177,HNRNPA2B1,RCBTB1,GGCT,ATP6V1C1,STX6,OR2A25,FANCG,PLA2G15,MAPK1IP1L,RFTN2,TPPP,SLC35E1,RB1CC1,CAPZA2,CCL8,YPEL5,PPID,CLDN22,EGLN3,DYRK2,FOS,RIOK2,MRPS28,POMP,RPL26,NFKB1,PAFAH1B3,HNRNPK,PRKAG1,LHFPL2,ACAP2,MAFG,SCD5,TNRC6C,SPTBN1,TOMM40L,EIF3J,FERMT2,GNPNAT1,GIMAP2,UTP23,CHI3L1,RNASEL,TNFSF18,PPDPF,DNAJC8,RAB33A,CRYGD,RNF167,FAM107A,OPHN1,SUMO3,CCR3,ZNF687,SFT2D2,CMAS,RAB23,PTGER1,RHOJ,CBLN4,WWP1,TMEM50B,JUN,IFNG,HIRA,S100A8,CD47,SLC6A11,RAB37,FOLR1,CAV2,CSTF2T,PSRC1,FBXO25,IFI35,C1QL1,TIMM10,STK38,AP1AR,RAB5C,PNP,PCDH19,WEE2,EIF4B,PTHLH,MRTO4,SLC25A4,SMAD3,PPP2R1A,ELMOD1,MLF2,PLEKHJ1,TIMP1,TXNL1,DERL2,TMEM59,IL6ST,LYNX1,RPL23A,KCNIP3,INPP4A,EZH2,ARCN1,FGFBP2,RAB9B,AMT,WIF1,FN3KRP,DYRK1B,PHYHIP,STAT6,OR10G7,ISG15,SNX24,ACADSB,BEND5,CMPK1,SNRPA,RAB2A,CTNNA1,GPIHBP1,WDR44,TRAPPC6B,VAMP2,CCNF,CRBN,CD226,SACM1L,VPS33A,B4GALT3,PDYN,ZFP1,TAF5L,MYEF2,PNPLA8,NGB,UQCR11,GLT8D1,MOV10,PCGF3,GPX5,TMEM14A,GDE1,CPSF2,CDH8,MRGPRX2,GRIA2,LRRC24,FLYWCH2,KLK5,LIX1,CAB39,DDX4,TMEM91,SLC43A2,ZCCHC9,TOP3B,HIGD2A,B3GNT2,TEX12,FAM168A,ACTL6B,UBE2D1,LY6G5C,SLC4A8,SNIP1,HRH3,ABHD13,ZBTB45,INHA,RPAP2,OR5L1,RGS5,RAB1B,NDE1,RBMX2,AMY2B,CCDC65,LDHAL6B,HMBS,CD2BP2,TDRD7,SLITRK2,ELSPBP1,STX18,RBFOX2,FOXN2,GK2,CDKN1A,OTUD7B,PPFIA3,SDHAF2,CLIC2,MED11,AKIP1,PIWIL2,SOS2,ROGDI,PGM2L1,GYS1,SLC23A2,TMED7,DNAJC3,RNASEH1,FKTN,KLK6,SLC41A3,SERINC3,STAU1,TSN,STOML3,CDK4,NPR2,NR1I2,CNNM4,DPY30,BRCA1,ABHD4,PCDHB1,KCNK13,RBM7,TRAF2,PDHA1,ADPRH,MBD5,KCNMA1,BCL10,NOS1AP,RGS2,STMN2,NME1,DUSP19,SLC32A1,PARP11,CEP97,ZNF501,IFRD2,ST3GAL5,POR,STK24,LCA5,RAC2,LRP6,TAS2R40,PYROXD2,MRPS21,IRF3,MTHFD2L,CD36,PCMTD2,KLC2,STXBP1,PAX9,PRKAB1,UQCRH,DPEP1,DERL1,IL18,SOX2,CSNK1A1L,ST3GAL1,PHYH,FUT9,RTKN,NTN4,HOXD12,RPLP0,UBE2V2,IL10,EFNB1,RNF113A,THTPA,SH3GLB1,PREPL,TSPO2,GOLGA7B,PELP1,ITGA6,CSNK1A1,COMMD8,TFE3,DEFB114,MT1M,IFNA10,SNAPC3,SNCG,BLOC1S2,SSU72,IGBP1,AKAP12,RAB40AL,DDX39A,TMSB4X,TRIM5,EIF4E,LHFPL4,CDKN2C,COX4I2,SPECC1L,KHDC1,NAT2,RINT1,TSPAN5,OR10G9,BZW2,ZBTB17,BCAP29,FABP7,CD274,EIF3K,B3GALNT1,CREB3L4,EED,ABHD14B,MRPS16,YAF2,ELP3,CIB2,MRFAP1L1,ACSL4,TGFB3,TRIM24,ZNF592,MTRF1,B9D2,EWSR1,GPX3,PROS1,TMEM204,EMP3,OSTM1,CHMP2A,CBR4,SLC19A2,VMP1,HSPA8,MSMP,GMPPB,ADO,CALHM2,TES,CCDC25,BECN1,LMNB1,HTR5A,TMX3,EIF2B3,DNAJC22,CHGA,GBE1,PAPSS2,TCF23,GPR65,SEC61B,TOM1,BCL7B,F9,NKX3-1,GCNT3,MYO6,CYP2C18,NDUFS8,GPR137,SNX17,BCS1L,APOO,TOP1,TMEM144,NRSN2,DSTYK,ZC3H7A,AIF1L,ZBTB5,TMEM123,CIDEB,ARMC7,ATAT1,TMSB10,IPO8,GPHN,ISG20L2,HSP90AB1,POLE4,ZNF862,ATG4A,SYP,CSRNP1,FUNDC2,MRPS23,RER1,FCN2,CDKN2AIP,RGS7BP,SFRP4,TFCP2,METTL2A,ABHD6,CLDN1,CCNB1,CTDSP1,FAM162A,NDUFAF4,CRYBB2,AKAP14,ALKBH5,ERH,ANKRA2,ADIPOQ,LCP2,CRTAP,UHMK1,EDEM1,GNG2,VAMP5,METTL14,MAP3K11,GTF2H2,MBL2,PTS,TOR2A,AMIGO1,JPH4,COL1A2,RMI2,SMU1,SLC35D1,R3HCC1,CSGALNACT1,SAT1,SDF2L1,RUVBL1,GTF2B,CXCL3,NKIRAS1,GIT2,CLDN4,SLC13A5,LAMB2,RAB3D,ZNF287,TMEM184B,KDM4B,ACAT1,TRIM54,FAM98A,ACBD7,CDC42SE2,RPLP2,TGIF2,GREM2,POPDC2,GPX6,OR4Q3,HTR1F,CREBBP,PRPF19,PDCD4,LDOC1,GPAM,RDH10,TMOD2,GNPDA2,TM4SF19,CRAT,NAPA,NOTCH2,SOBP,PTPN11,DECR2,AVL9,IQCK,TP53INP1,VEGFA,FAF1,REN,CCR1,SMPD2,SOD1,TBC1D13,NCBP2,ATXN10,ASTN1,DTWD1,DRGX,SHOC2,HDHD3,DDRGK1,RPL32,PSMA1,AK3,CLCN6,HMGCS1,SLC25A12,HARBI1,TMED5,USP16,PFDN2,TCEAL1,LTB,TRIM68,ETF1,LRRC8B,TAF10,PRDX1,FAM53B,PREB,NPW,NFKBIA,TUSC1,ATG7,RNF34,ACBD6,DENND2D,COPS7B,KLF4,SERPINC1,HLF,ACP5,EGFL7,TMEM59L,ATP6V1A,SLC7A8,RFC3,FBXO22,REG1B,GPM6B,UBE2W,DHRS13,PARL,GTDC1,UBIAD1,LRRC61,POLR2B,TSNAX,TEX264,SNRK,UBLCP1,GSTA1,SRSF2,SERPINB1,TRAK2,ST7,AVPR1B,KLF9,STUB1,PIP4K2C,ACVR1C,FAM181B,NKIRAS2,TMEM41A,IL1R2,SLC22A17,TNKS,CYP1A1,ST8SIA5,PLS3,BST2,PPP2R2C,SPON1,STK4,HINT3,VRTN,SLC25A10,GTF2H5,RPRD1A,DDX50,ZNF821,TRMT112,SLC35F2,SYNCRIP,DIO1,VGLL2,SLC16A10,CLDN9,PRICKLE2,MSTN,RPL27,PPP1R1A,PTH2,MTF1,FAM83C,ABCG2,MRPS9,LTA,SPSB3,TOR1B,MNS1,POLB,POLA2,UBASH3B,CCNH,SEMG2,KIAA0513,IFNB1,BTN2A2,UBL5,CSH1,USP3,CAPN1,ASZ1,METTL22,CYP2C8,TNFRSF1B,CDNF,TGFBR2,SPIN3,ANP32A,RPL23,CLLU1,STOM,CTTN,HP,SEMA4C,SLC2A3,RABGGTB,FBXO7,RCL1,IL2RA,PPAN,AQP2,SMAD1,CLEC18A,CHST13,ZNRF1,PPP2CB,KLHL24,FKBP8,GABPA,PRSS12,PPP3R2,TIMP3,MPDU1,VAMP8,TMEM70,TTL,PMM2,PRMT6,EP300,ADAMTS10,PEA15,RNF8,AKAP8L,APOBEC3F,PLCB2,MAP2K1,HSD17B6,COPS5,STAT5A,PRDM4,FEZ1,EIF4A2,MAGEH1,OTX2,LRRC3B,FPGT,SOSTDC1,MORC2,ELOVL1,SSR2,SNRPB,TPM3,EFNA3,PTPN4,GPX7,CHRNB2,RIT1,OR10P1,FAM43A,NLRP9,RNASE1,TMEM45A,TMEM237,LAMP2,IFI6,AR,OR8B12,PPM1K,CCL2,LLPH,GSTP1,CLEC2B,CBR3,ADD1,KLF1,VDAC1,CLPB,FEN1,ODAM,APOBEC3H,LANCL2,GLRX2,ASB7,PRKACB,ZNF326,MYBL2,PLEKHO1,ERAS,GSTM5,CNOT2,CRHBP,PKP4,GPR176,CLDN12,ELF5,CCNY,CHKB,FCGR1A,VGLL4,DNAJC19,SCML2,MTM1,BIRC2,FCGR2B,NUDT7,IFIH1,CER1,POLR1B,SIAH2,CHCHD6,HOXC4,UPK1A,RFXAP,EPS8,SS18,MRPL22,CDCA7L,UMPS,RAB19,CD1C,UBP1,MAVS,KLHL22,CHMP4C,SOX14,PDAP1,SLCO2B1,CX3CR1,IGF1R,FAM177A1,DCTD,SCNM1,MCM4,NR2E1,DROSHA,FLOT1,THOC2,STARD4,PGGT1B,SLC38A7,KCNC1,FBXL19,LAPTM4A,MRGPRX3,MTA2,CCDC86,SUFU,CHCHD4,CHIC2,SLC16A1,HINT2,NUF2,TMEM101,TPD52,DBT,RAPGEF5,ELOVL7,DAPK3,DSTN,RPS27A,PCDHB13,G3BP1,CHAC2,POP5,PSORS1C2,METTL21A,MRPL18,FGFBP1,MFSD5,OLFM3,SCG3,BMPR2,COMMD3,RND2,PPP1R1B,SCGB1D1,SHISAL2B,NLRP3,ILDR1,CCS,RASD1,IER2,CHPF2,NDUFAF3,DKK1,HERC4,NR2F6,CNTN2,ASNSD1,ZMYM3,CRIP1,PSMB1,ZNF365,BAG3,ORC5,ILF2,RPS16,KRAS,RRM1,RBM22,TOM1L1,KDELR1,REEP3,ST6GAL1,CSGALNACT2,RPL7L1,CSTF3,HENMT1,TMEM179B,TOMM22,BFAR,UBA3,CBLL1,TOR3A,GLRX,PRR3,IL22,TAGLN3,SAV1,STAT2,PCDH17,EPCAM,SRSF7,CST11,FASTKD5,SFXN2,SNX22,TMEM170B,TMEM117,MRPL34,NDUFB6,GNAO1,NCDN,UBL3,IMP3,GNPDA1,KCNJ3,B3GALT1,COMMD6,TMEM30A,AFAP1L2,CCDC134,TCF19,SLC30A7,SLC6A6,TSPAN18,RPS6KA4,GANAB,BBS5,XCL1,OCRL,MAT2B,MLC1,ZNF664,PDHB,DDX46,DHX15,RHEB,FBXL14,TRIM15,RELL2,RAB27A,GRAP2,RPS7,PSMD4,NPPC,LRRTM3,DAAM1,MRPL11,SCLT1,PPP2R5E,SH2D1A,UBB,SLC11A2,LMAN1,NPSR1,HSPA13,ANKRD34B,LARP4B,PMP22,SERPINA1,OR2Y1,STX11,FBXO44,DKC1,ARPC3,LRRC3,HR,DNTTIP1,AGPAT5,PL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URKAIP1,FXR2,TM9SF4,TCEANC2,LRRC1,NUP37,FERD3L,USP5,MXI1,ITGAV,GPBAR1,PPP2R3A,GPR85,SLC1A3,SLC22A8,SMAD4,DRD1,FZR1,RILPL2,DRAM1,VKORC1L1,IL1RAP,CNPY4,SMARCA5,FAIM,ELK4,ATP1B1,BAK1,DYNC1I1,HECTD1,LGR4,FGF10,TLR2,IL6,PPP1R12A,CCDC122,GRID1,RERE,GABRB2,ARMC1,TFEB,CES5A,SYVN1,HSCB,RPAIN,UNC119B,TBC1D4,MORN4,GIMAP4,NDUFS3,HPGDS,RLN2,GOLGA5,OSBP,DNTT,PSMC1,MED21,TWSG1,TTC32,SSRP1,RIC3,DES,ARHGAP25,ZRANB2,PCDH9,LIN7B,MYOZ3,EIF4E3,TCAP,VTI1B,GLT8D2,FAM162B,SPATA6,ZNF575,CCL20,MRPS7,ARHGAP5,RPL35A,RSRC1,CD248,ZNF668,KLHL12,IDO1,PPM1D,SERPINI1,SLC39A3,SLC25A28,FLCN,MSL2,CXCL12,STIM1,GRPEL2,LRIF1,TMC7,FTL,TNFSF13,FLRT3,DHPS,RRN3,UTS2,GNG5,TMEM14B,NIF3L1,CYP27B1,PNOC,NTPCR,YBEY,MRPL10,IL15,ARL6IP6,TLE1,BTF3L4,HMG20A,RIMS4,NDUFA2,IFNGR1,MOG,PLSCR4,LRRC57,NMI,SCN3B,PADI2,POLR2F,POMT2,NDUFB10,TMEM190,NSFL1C,OGN,SCPEP1,NLRP6,CHRDL1,PSMB6,ZCCHC17,PEG10,IZUMO1,PIP5K1A,TRAF3IP2,TOMM20,PTGER4,DHRS7B,BAHD1,TERT,MORC4,CISD1,PIK3R3,LANCL1,MKKS,SLC35B4,MPZ,VPS28,SRC,CD2AP,RASL10A,METTL6,OR51M1,GNG13,TUFM,IDH1,IFNA2,HMX2,CHST11,NEUROG2,MTMR6,SEMA6C,CCDC85B,LUM,ICAM3,UNC50,MED31,SH3BP5L,RPL7,TUBA1A,YTHDF1,CELF6,NAA50,FCGR2A,ENTPD3,RASGRP3,MGAT1,RCE1,RGS19,IFIT2,RAB33B,SECISBP2L,MCM3,RNF115,CDC42EP3,PAFAH1B1,SLC25A11,KCTD15,MS4A7,HNRNPD,PDCD1,PSMD12,CCT7,CKLF,OR4A47,DCTPP1,CD34,FBXL4,THAP1,UNC79,CPXM1,EID2B,PRCP,TRAF3IP3,PIWIL1,CCDC90B,RGP1,TAB2,SRPK2,YPEL4,LDB2,PRSS8,GADD45G,RPA2,TMEM107,SLC6A2,TNFSF15,AIP,CD40,CRY1,NOG,ARFGEF1,MED22,TLR8,PMPCA,PYCR2,TNFSF8,CDIPT,ZNF428,PDE2A,CDK7,SIN3A,SCAND1,PSMD7,PLAC1,RGN,CTTNBP2,RAB6A,CYP4V2,APLNR,CNPY3,SRI,NCAPG2,PSMD3,DTWD2,GPR160,POLR1D,RNF10,OR51E2,GP9,KRTAP8-1,POLE3,TEX261,ZDHHC16,MDFI,PPP1R11,RAP2A,MSH6,FBXW4,CD209,ST3GAL2,TAS2R7,PTGFR,IL2RB,IP6K1,SPINK9,SLC25A24,SSNA1,GK5,GLCE,STAR,TRIP4,RPL10,PDCL,SUPT5H,MPV17L2,CRYBA1,WDR45,THAP8,NRM,HSPA5,SERTAD2,GNA11,HSPB6,FAM20B,TICAM2,FHL3,PPWD1,GPRASP2,PQBP1,TRIM44,NR1I3,PAIP2B,LRP10,CCDC3,VAV2,BTG2,ITGB8,TMEM229B,NUFIP2,CMC1,HINFP,GNB3,DPEP3,TMEM183A,BTG3,CD9,RUSC2,GRPR,IGFBP3,GADD45A,RBMS2,TGFB2,SLC25A27,VPS54,S100A11,ATG9A,ZNF622,THOC3,PIGA,GLOD4,BOLL,MX1,SAP18,EXOC3,TMEM81,CAP2,SLC22A6,TIA1,SPG21,DDR1,EIF1AX,HSPD1,RNASEH2C,PNPLA4,PIAS1,NPC2,TMEM115,PARD6A,TCEA2,LRRC28,MBD3,CDC23,DMPK,SYNGR3,TANK,BRAP,MPG,RDH11,PIH1D1,KCTD3,ELFN2,RP9,GALC,HAUS2,CNPY1,GNGT2,SSPN,LRRC8A,LBX1,NKAP,SNRPE,RRAGB,GRIK1,CMA1,DLGAP4,ANXA4,RASL12,IL18BP,GALNT2,GORASP2,THUMPD1,PELO,GMPS,TTC9C,IGF1,CCR7,SNAP25,RXRG,MRPS17,SGIP1,MECR,MRPL9,UBE2G2,FEM1B,UPRT,SUPT3H,FXN,TOX4,KLRC2,RAMP3,CPNE2,IFT172,CYTH4,TMBIM1,IER3,NUCKS1,CENPL,TMEM165,KLHL25,SULT1B1,RPE,VEZT,SLU7,MFAP3L,FAM3C,PTP4A2,IRF7,PRR13,SLC25A5,TOPORS,LYZ,WSB1,ADCK1,MACROD1,ZNF518B,CYBRD1,FAM151B,SLC35E4,FAM136A,MGMT,TRAPPC6A,MDC1,MTCH2,ITM2B,SP1,IMPA2,TADA3,TRAM1,TMEM196,UBA52,AP1M1,FUNDC1,ECHDC1,SPRY1,RPS10,CLDND1,ETNK2,CCDC106,TRAF6,TBCCD1,KRIT1,VPS72,KCND3,FUBP3,ROCK2,TKTL1,GIN1,RPL18,ZNF581,DUSP3,SUCLG2,PDE7A,KIF3C,ATP8A1,CIAO1,VPS18,GHRL,NAA16,GJC1,SLC12A2,RUNX1,RPS20,SCML1,ZFAND6,MED10,TYMS,TAPT1,SRFBP1,EIF5B,PFKFB2,ARHGAP12,MREG,ACER3,DIRAS2,YTHDF2,ANKRD6,PDE12,FAM161A,LMO2,FKBP1B,LCORL,EDA2R,MAGEC2,PSEN1,KCTD17,CLEC6A,RASSF8,SSBP4,TLCD1,AQP11,RBP2,PIK3CA,IVNS1ABP,FAM83B,SNRNP40,JAKMIP2,PSMC3,CDH11,TMEM185A,NDUFS2,AP1S2,LY96,TMEM47,MAD2L1BP,AKR1B1,TAB1,SF3B1,APEX2,ADORA3,ZBTB39,RBM27,CPT1B,CNN3,ANKMY2,PIK3AP1,XAF1,COX6C,PICALM,LST1,VTA1,RPIA,COCH,FEM1C,NUDT2,ATP1A3,BAX,GH1,PEBP4,PSD2,CRTC2,GSTM4,TSPAN15,TMEM38B,NPM3,TRPC1,ELMO2,LYPD6,BCL9,ASPA,DR1,CBX3,GTPBP8,HS2ST1,MIS12,GABRA1,PRNP,HSD17B10,CAND1,TMEM89,TPPP3,ZNF263,SNX10,CA2,MTDH,USP6NL,SGTA,TMED9,E4F1,GSTCD,DLST,GTF2F1,SSX2IP,BCL6,SYNPR,PRL,MPPED2,CDC7,SLC19A3,OLR1,NDST3,FBXO8,MGAT4A,RBBP8,SGMS1,MRPS34,CYP2C9,IGSF11,DUSP21,ATAD1,TRIM45,CDC20,WDR5B,ZDHHC4,TIMP4,ACCS,XRCC5,SNRPG,TBC1D25,PEX13,AIPL1,SLC35B3,FHOD3,WDR11,NHEJ1,TYROBP,SEC13,IL2,VMAC,TNFAIP8L1,NBN,CD81,LRRC40,DPH3,ELK3,CRISP1,MT1E,UBE2E2,FSTL1,POLR2L,POLDIP3,RHOBTB3,HGS,DBR1,TAS2R13,RNF133,TMEM170A,COX6B2,TSPAN17,PRKRA,GNRH1,WDSUB1,PRKCE,ZNF451,RPL26L1,PHF13,CGGBP1,FOXA3,KLHL1,SESTD1,CARTPT,BANF1,ABHD12,NF2,PARP2,GGH,TNF,PPAT,IL17F,CYGB,NUDT9,TFB1M,SNRPB2,LZTFL1,KLF3,CHRAC1,CCR4,CORO6,TRIM29,RB1,PNMA3,DPH5,FAM53C,MCL1,HCAR1,TMEM127,GSTA2,HFE,DDAH1,GPR35,NDUFA1,ALG11,PAQR3,CREBZF,TRIM36,MRPS18C,NT5DC1,PROK1,JAK2,CBLN1,STK3,COMMD9,HSPB2,LY6H,LILRA2,TNKS2,PTP4A3,PLSCR1,DCAF12L2,AKR1C1,MRPS11,CSNK1G3,RAB39B,PRND,CPLX2,HUWE1,ABHD10,CNTROB,FTSJ1,SREK1IP1,PMAIP1,TTPAL,UBE2L3,CCIN,MEPCE,EIF3G,CYP3A43,SPEM1,PDE4B,B4GALT4,CAV1,TCEAL8,LXN,YIPF3,RPS2,ITGB5,RGL2,TRIM34,TMEM205,NDUFC2,NINJ1,ICOS,EHD4,ZNF511,CEND1,FAM81A,SLC25A1,HNRNPF,STAMBP,HOMER3,CXCR3,MAGEB10,PCGF6,GRM1,SLCO3A1,ADORA1,SPATA2,KCNJ10,SHPRH,TAF1D,MAGED2,GJA1,SURF2,SLC29A1,AASDHPPT,REEP4,RNF222,TM4SF20,CCNA2,CAPN2,LSM14A,SLC8A1,ABHD8,ICAM2,YWHAZ,STARD3NL,TM4SF18,TNR,BOK,PLCB1,GPC1,GPR17,PRSS23,ZNHIT6,ARL2BP,ING2,FRZB,SPP1,TSR2,CHRM3,DMTF1,PLG,DLK2,CDK12,PSMB7,FBXW7,TNFAIP6,EPHA4,CTU1,KCNJ2,GXYLT2,TXNDC17,CITED1,ARL4D,LIAS,CPLX3,TNNI3K,GCLC,PSMD10,NPY1R,PPIL3,PHTF2,ZCCHC7,CTSA,DPAGT1,LPCAT3,GPR83,KCNIP2,SERTAD1,ZHX1,HNMT,FA2H,ERRFI1,MRPS26,PHF7,HMGB1,TUBA1B,CKB,THAP6,ARF1,EIF2B2,ZMYM6,GNG11,BTBD10,ZBTB26,LRRC14,EMILIN1,PRDX3,PDCD5,COX7B,CDC42SE1,BGLAP,SDHC,RGS1,ASB11,FAM83A,RHOG,NOL12,TTR,SEC61A1,GAD2,RSBN1L,METTL18,SMUG1,SVIP,ASCC1,CDH7,ZNF770,TPD52L1,DUSP18,UBXN2B,MAEA,FOXD3,LYRM2,FBLN5,ZNF345,EID2,KIAA1958,CXCL10,DICER1,MAGEB1,SLC6A7,IL21,RPL19,ZNF362,FGF16,HBM,POU5F1,MSN,DDIT4L,RNASE4,SAP30,SLITRK5,GLIPR2,SPCS1,TDP1,MID1IP1,SERINC1,SNRNP70,PLEKHF2,LAMTOR2,SLC41A1,PNRC1,TMEM106B,UCP2,UBE2I,MED29,MXD1,MFAP1,MAP3K3,FHIT,ARL11,EZH1,ARGLU1,RNF7,MRPL16,TECR,FGR,MRPL12,RCHY1,SPHK2,FAM20C,ZDHHC24,ARF6,B3GALT2,PPT1,DOK5,MAP2K3,SEC22A,DCTN4,RPL7A,CXXC1,FIG4,LSM12,ASPM,EFNA5,ZC3H14,CBFB,CETN2,TADA1,ZC4H2,PITHD1,SMARCE1,LEP,SH3BP4,RIT2,CACNG3,PDE6D,OR5K1,PDZK1IP1,TNIK,S100B,LRFN3,UBE3A,CCL24,SNRPD1,ALCAM,JUNB,PTPN5,UFSP1,SMAD9,RELL1,TIMM17A,RNF182,LIPA,MCCD1,SLC39A10,BCAS4,HM13,PGAP3,MB21D2,LCN15,VCPIP1,SRP72,DDIT3,SLITRK1,CACNB2,HCFC1R1,RPL28,EDEM2,FIS1,ARFGAP1,PIGC,MVD,STK38L,CYP4F22,PREP,CDC26,SHC3,SPATA4,CMTM7,CA12,SLC7A1,TBC1D16,FMOD,ADRB3,RAB11B,ARL6,STX5,CCND3,CSRP1,IRF4,LEMD3,HSDL2,LYPLAL1,OPRL1,RNF139,SMG5,ABCF1,DUS4L,PLP2,DYNLL1,HINT1,TNPO2,PYCR1,THOC6,CCL11,RAB9A,RXFP2,RPAP3,MARCKSL1,SLA2,SDR16C5,IFNAR1,GPR37,ESD,CDKN2D,ATP6V1D,VWF,CDK17,PSMB10,ART5,TMEM39A,VPS39,SUPT4H1,FAM174A,MYLIP,SART3,IFI16,PTPRZ1,CLP1,CLPX,ATG3,INA,CFTR,BMPR1B,HS3ST1,TULP3,MPP1,BARX2,PSMD1,RANBP10,MED27,SRM,ADH1B,BLVRA,CRYBA4,RAB32,PITPNA,FOXC2,CRYZ,PCBP4,MLH3,APOBEC3B,SEC14L5,RPL4,SUV39H1,RGL1,DYNLRB2,CKS1B,HBP1,SLC25A3,RWDD1,COPE,RBM41,PRKCB,IRF2BPL,LSM5,DCTN3,HCFC2,PABPC5,GCHFR,GJB1,KRT8,PRELP,CSF2,PCYT1B,SKP1,CHCHD2,IZUMO2,ZNF200,TPST1,AGGF1,LCP1,HNRNPH3,SIGLEC5,HDAC11,ATG16L1,TP53TG5,DIRAS3,TTLL10,STAP1,ACTR1B,HTR2A,SMARCB1,SDHAF1,ALG5,SUGP1,ABCC2,STARD5,FMO1,SRD5A3,CLRN2,DCAF16,GTF3C4,MMP20,REG1A,C1QL2,PLCXD3,DNM2,SOX9,KCNG3,CHST10,AKT2,GAB1,ITPRIPL2,PSMC5,APEX1,PRSS1,RFC4,LCN1,TLR5,TICAM1,HS3ST3A1,GPM6A,COTL1,PNPO,ETFA,PRELID1,RIMKLB,AQP3,ECD,CD59,AMELX,VSTM4,NEU1,PDCD1LG2,RAB1A,GLO1,FBXO31,VSTM2L,ZDHHC17,MAP1B,CNOT8,PELI1,PIGK,MLN,KLF12,WDR12,IAH1,TCTA,PCP2,ADD2,SOD2,SCN2B,TEF,ANKRD10,ZNF343,WBP11,ZNF436,EGR1,DIO2,STARD7,CHTOP,SYPL1,GPR75,SETD3,TMEM126A,ACTL6A,FOSL2,GNPAT,ACP2,NPBWR1,RPSA,PIK3CG,RHOH,ARHGAP15,ERLIN2,HYAL2,UBE2S,RRP7A,CCDC126,RBM3,RACGAP1,CORO1C,MAGEA4,STT3A,MRGPRX1,LIPT2,HPCAL1,NAP1L5,SEMA7A,TRMT5,OR9I1,BCKDK,MED4,ZCRB1,APOC2,CYB5B,DIS3L,CA14,OSBPL8,CEP57L1,ARHGAP19,TACR1,NACC2,CHRM5,EMILIN3,MTA3,DRD3,NAP1L3,CEACAM5,TIMM13,RPF2,XBP1,GPR34,TBC1D1,PDLIM4,THG1L,ERCC3,GABBR1,PRSS35,FKBP2,UNC45A,TBCEL,CYP26A1,GMNN,ISG20,RALB,TMEM87A,NUDT1,PSMG2,DTL,TNFAIP8,CTDSPL2,ANKRD46,CEP70,ABHD2,ARL6IP5,SNRPA1,CCDC22,KDM1A,NDFIP1,LDB1,NRGN,CSRNP3,TRAPPC3,GMDS,WNT2,BIRC5,MFSD3,VPS26B,YKT6,ANKH,ARL5B,ESYT1,F2,SAP30BP,HAPLN2,EDC3,AANAT,DLG3,RHOU,TMEM176B,RPL22,CEBPE,ATF3,RBM5,CTLA4,RANBP1,ACSS2,DEFB1,IFRD1,PDLIM3,PRSS37,MAP1LC3B,GFM1,HOXB8,SSH3,SEC61G,EMX2,CENPM,SLC7A11,POPDC3,RETSAT,FZD6,MET,PRM1,GAL3ST4,ADIPOR1,TIMMDC1,MT1X,UBE2V1,SERPINB9,RPLP1,SNX11,PDE6A,HELT,TRNP1,IMP4,PHOSPHO2,SCG5,TMEM198,TRAPPC2L,RFX5,MAT2A,NMRAL1,CMBL,CDKN1B,TAF9,MEA1,SCHIP1,KCTD16,SLC15A1,PLEKHF1,AHSA1,ZBTB6,TEX19,ZNF655,TRIM62,HNRNPAB,GPR78,TMEM220,ST8SIA4,TMEM168,CD200,SIAH1,LRP3,STRADB,NCK1,NETO1,PTGER2,CDR2,C9orf72,NAA30,HERC3,PSMB4,DOK6,SEMA3C,IRF9,HSD17B8,LSM4,CGRRF1,DDX39B,RSL24D1,TRAF1,SKAP2,CLK1,SERPINA3,KCTD20,RASSF4,ZMAT3,BRS3,HAS3,OLA1,PRPS1,BAD,TSPAN3,MGST3,UQCRC1,NOC4L,CRHR1,AKR1E2,SSBP2,PDCD10,GDAP1L1,LRRN4CL,ZSWIM7,RPL31,WTAP |
| 5.341e-16 | -35.17 | RPL6 (ribosomal protein L6) | protein interactions | 6128 | 534 | 236 | 19454 | 5460 |
RPS3,PSPC1,RPL10L,MRPS21,RPS17,RPL7A,UBE2H,TRIM23,CISD1,MECP2,RNF113A,RAB9A,TRIM3,RPL27,BAP1,HSPA5,RPS15,CFTR,MRPL10,RPA2,RPL32,MRPS9,SURF6,TMPO,RBM42,RPS27L,CAND1,DNAJC1,RPS16,FZR1,API5,COPS5,CSNK2A1,CD81,ENY2,RPL10A,RPS2,SNRNP70,RPL24,H2AC4,TUBG1,DHX9,RPL3,SNIP1,RPL17,MEPCE,NEDD8,H3C1,MRPS33,H2AX,MTCH2,RPSA,MRPL47,TP53,UBL4A,KBTBD4,DNAJC2,RBM34,TFCP2,MRPL13,NFKBIA,NFKBIB,RPL10,MATR3,BTF3,HNRNPC,MYC,DNAJB6,H1-1,RPS26,ICAM1,FTSJ3,RAB5A,HSPA8,MRPL34,RPS28,NGRN,MRPS7,STAU1,UFL1,FBXO42,RPL27A,PIH1D1,PPT1,MRPS18A,HSP90AB1,LYAR,RPS10,DDRGK1,MRPL9,XPO1,WWP2,IFI16,MAGOH,DRG1,NCK1,AGR2,IKBKB,PABPC1,RPL31,CBLL1,RPS4X,RPL28,KRAS,H1-6,EEF2,RPS7,DNAJC25,SOX2,H1-3,MAGEB10,RPS23,RPL18,PTEN,RPS20,RPS12,PRKRA,GSK3A,EIF2AK2,EIF4A3,METAP2,CCNF,RPL22,RPL13A,NDN,TUFM,USP14,DNAJC8,PPP1CC,RPL26,FBXO7,DNAJC19,IVNS1ABP,MTDH,KIN,SIRT7,RPA3,UTP23,AATF,BRIX1,PIAS1,HMGB1,FBXW7,RPL4,GTF2I,NPM3,CDK7,RPS14,RPLP0,RPL26L1,METTL14,LMNA,MRPS34,RCHY1,KRR1,RPL12,CTDSPL2,SRP14,NAP1L5,MRPL24,MRPS23,ZBTB2,MDM2,CDK9,RPL35A,DCUN1D1,HDAC6,NFKB1,MOV10,ESYT1,RPL23A,SMN1,RIGI,MRPS18C,RPS13,VRK1,NOC4L,HUWE1,RPL15,EEF1A1,MRPL11,FBP1,MRPL49,SRP72,MRPL51,ILF2,RPS9,SEC61B,RPL37A,RPL19,RPL35,ZNF668,CUL3,CUL2,RIT1,HSP90AA1,RPS5,BRCA1,FYTTD1,NMRAL1,G3BP2,COIL,GPC1,EMC9,RPLP1,RPLP2,PHB1,RPL8,RPL9,FOLR1,SRSF10,RPL7,KCTD10,NOP58,MAP3K14,TRA2A,MRPS35,RPL23,AHSA1,MRPS26,RPS24,MRPS11,SLC25A5,TRIP4,RAD21,RPS27A,TRIM37,TNF,G3BP1,OTUD6B,RPL29,B3GNT2,SART3,RPS11,CHMP4C,EZH2 |
| 5.739e-16 | -35.09 | RPS2 (ribosomal protein S2) | protein interactions | 6187 | 588 | 255 | 19454 | 5460 |
PHB1,RPL8,FOLR1,RPL9,DNM2,RPLP1,RPLP2,RPL7,FGF1,TRAF6,RPL23,DICER1,AHSA1,RSBN1L,RB1CC1,FGF3,GADD45A,TRIP4,SLC25A5,RPS24,MRPS11,TRIM26,G3BP1,EIF2D,RAD21,RPS27A,B3GNT2,RPL29,EZH2,SF3B5,POLR2C,RPS11,ZNF22,FAU,RPS9,SEC61B,RPL37A,RPL35,RPL7L1,RPF1,DYNLL1,MRPL23,RPL19,CUL3,CUL2,ACO2,RPS29,ZNF668,BRCA1,ZCRB1,RIT1,RPS5,NMRAL1,NOP53,GPC1,YTHDF1,G3BP2,COIL,NOTCH2,TOR1AIP2,H1-5,WDR77,CDKN1A,EMC9,ANXA7,RCHY1,KRR1,RPL12,NAP1L5,SRP14,PRR3,RPL35A,DCUN1D1,MDM2,CDK9,EMC4,SPATS2L,MOV10,HDAC6,MPHOSPH10,NKRF,RPL23A,VRK1,PAK1IP1,SMN1,EIF3E,RPS13,MRPL22,FBP1,RPL15,FCF1,EEF1A1,LLPH,SRP72,ILF2,EIF2AK2,EIF4A3,METAP2,CCNF,PELP1,PTEN,RPS20,RPS12,PRKRA,GSK3A,RPL13A,SLC25A4,NDN,VIRMA,RPL22,TUFM,PPP1CC,RPL26,FBXO7,SAYSD1,SIRT7,RPA3,FBXW7,HMGB1,RPL4,NF2,UTP23,AATF,PIAS1,UBA52,TPT1,RPS14,GABARAPL2,CDK7,METTL14,LMNA,JUP,RPLP0,RPL26L1,ZNF574,YBEY,NOB1,RPS10,HSP90AB1,WWP2,RPL6,IFI16,CTNNB1,NGDN,DDRGK1,YWHAG,XPO1,AGR2,DRG1,MAGOH,RPL31,RTCB,RUVBL2,KRAS,H1-6,RPS4X,RPL28,EEF2,RPS7,H1-3,PTRH2,RPS23,RPL18,CMTR1,SF3B4,MATR3,ATP5F1B,RPL10,SFN,APOBEC3B,MYC,BAG3,BTF3,H1-1,NSA2,ICAM1,RPS26,RPS28,PYM1,DDX39B,SF3B1,HSPA8,STAU1,UFL1,FXR2,TIMM10,RPL27A,MRPL12,PPT1,PIH1D1,RPL32,EEF1B2,RPS27L,RPS16,CAND1,SURF6,DKC1,TMPO,RBM42,RBM17,ENY2,API5,GPRASP2,CD81,COPS5,CSNK2A1,RPL24,SNRNP70,TUBG1,USP15,RPL10A,MAP4,NOL12,SNIP1,PALM2AKAP2,MRPL52,MAP1B,RPL3,RPL17,MEPCE,RPSA,TP53,IMP3,UBL4A,ATP5PB,H2AX,DNAJC2,RBM34,TFCP2,RPS3,PSPC1,FGFBP1,RPL10L,RPL7A,ZSCAN25,RPS17,RC3H2,TRIM23,SPOP,EIF3G,UBE2H,IGF2BP1,BAP1,RPL27,RNF113A,RPS15,HSPA5,SPTBN1,CFTR,FGF13,RPA2,ZNF770,HEXIM1,DYRK2,UBE2M |
| 6.147e-16 | -35.03 | pancreas-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-ductal_carcinoma | 15565 | 4592 | 16828 | 4835 |
SNX18,TYW3,LNX2,RFC2,ZER1,CNTN1,GNB4,CPNE1,MATN4,DDAH2,ACTB,CCSAP,RPS13,UGDH,PGAM1,AP2S1,RNF121,CHCHD3,NFKBIB,ZNF280B,MMP21,EID1,EPO,DCUN1D5,FNDC9,PPIH,HDDC2,CD1A,HSP90AA1,PTPN22,SOCS3,FOLR2,PDRG1,PPP4C,NRBF2,PPIG,UBFD1,GSTM2,NAA35,GGT7,GRXCR1,DNAJB2,PSMA2,EFHD2,RAB30,RSAD2,NICN1,SST,COMMD5,PFDN4,GABRA2,CNR1,NPY,CAMLG,PLA2G12A,ZBTB2,MFN1,DAD1,TAS1R2,PAIP1,SSRP1,OCIAD2,TWSG1,MED21,PSMC1,DNTT,OSBP,GOLGA5,RLN2,OR9K2,NDUFS3,HPGDS,GIMAP4,MORN4,TBC1D4,UNC119B,HSCB,SYVN1,CES5A,TFEB,ARMC1,GABRB2,RERE,GRID1,CCDC122,PPP1R12A,IL6,TLR2,FGF10,LGR4,HECTD1,DYNC1I1,BAK1,ATP1B1,ELK4,FAIM,SMARCA5,IL1RAP,DRAM1,VKORC1L1,FZR1,RILPL2,SMAD4,DRD1,SLC22A8,SLC1A3,GPR85,PPP2R3A,ITGAV,MXI1,USP5,FERD3L,LRRC1,NUP37,TCEANC2,TM9SF4,AURKAIP1,AKR7A2,FOXP4,RNF126,TMEM182,LDHB,RPF1,UBE2M,PIR,TRIM10,SLC6A12,UBE2E3,AGAP1,FCHSD2,ISCU,ELAVL2,OR5AP2,MOSPD1,RAB22A,AK5,TNNC2,GTF2E1,OR8I2,SMC4,KBTBD4,PNO1,CYP2F1,PSME1,CLVS1,FAU,SCPEP1,OGN,NSFL1C,TMEM190,NDUFB10,POMT2,POLR2F,PADI2,SCN3B,NMI,OSGEP,LRRC57,PLSCR4,MOG,NUP50,IFNGR1,NDUFA2,RIMS4,HMG20A,BTF3L4,TLE1,ARL6IP6,IL15,MRPL10,YBEY,NTPCR,PNOC,CYP27B1,NIF3L1,TMEM14B,GNG5,UTS2,RRN3,DHPS,FLRT3,TNFSF13,FTL,LRIF1,TMC7,STIM1,GRPEL2,CXCL12,MSL2,FLCN,SLC25A28,SLC39A3,SERPINI1,PPM1D,IDO1,KLHL12,CD248,ZNF668,RSRC1,RPL35A,ARHGAP5,MRPS7,CCL20,ZNF575,SPATA6,GLT8D2,VTI1B,TCAP,EIF4E3,MYOZ3,LIN7B,PCDH9,ZRANB2,ARHGAP25,DES,RIC3,CKLF,CCT7,PSMD12,PDCD1,MS4A7,KCTD15,SLC25A11,PAFAH1B1,CDC42EP3,RNF115,MCM3,RAB33B,SECISBP2L,IFIT2,RGS19,RCE1,MGAT1,RASGRP3,ENTPD3,FCGR2A,NAA50,CELF6,RPL7,YTHDF1,TUBA1A,SH3BP5L,MED31,UNC50,ICAM3,LUM,CCDC85B,SEMA6C,NEUROG2,MTMR6,CHST11,HMX2,IFNA2,IDH1,TUFM,OR51M1,GNG13,METTL6,RASL10A,CD2AP,SRC,VPS28,MPZ,KRTAP12-4,SLC35B4,MKKS,PIK3R3,LANCL1,MORC4,CISD1,TERT,BAHD1,DHRS7B,PTGER4,TOMM20,TRAF3IP2,PIP5K1A,IZUMO1,PSMB6,ZCCHC17,CHRDL1,NLRP6,CXCR6,GNA14,CISH,TXNL4A,TSC22D3,USP14,NANP,ASB3,CHMP5,ZMYM4,EIF2S2,BTG1,AGPAT1,ANAPC13,CNTNAP1,TMEM176A,HDAC6,PBLD,RNF39,DUSP26,EYA3,ACTL9,GTF2A2,MICB,NUP153,TOR1AIP2,STOML2,OTUD6A,GPR15,PPARA,COPS7A,RNF20,POLR3F,RPL35,FRS3,RERG,TPT1,SNCB,ATL1,RRAS2,STXBP6,TPBG,KCNQ5,PDE1A,DAPK1,LILRA1,SLC25A17,NFYB,ZCCHC12,ARRDC3,LRWD1,CDSN,SESN3,PSMD14,YWHAB,THY1,ZNF692,SLC25A44,TBC1D24,ST6GALNAC3,EDNRA,PHB2,MMADHC,TTC1,NR1H2,BMP1,PRPF31,LEPROTL1,TMEM95,SYT2,SPOPL,TSG101,MAMDC2,ADCY2,MOBP,PKIG,DRG2,THBS3,SNAI2,CALR,TRUB1,HEXB,SYNGR4,PPFIBP1,NDUFA4,CYTL1,SLC45A3,SHMT1,OAF,SLC6A4,PDSS2,YIPF5,TOB2,FNTB,NME4,ODC1,SLC25A23,DSN1,ZC3H15,SFTPC,SNAPC5,RPP21,NDC80,CYB5R3,PLAC8,CDK5,GNG3,MRPL51,PATE2,RNF26,RAB13,OR10G2,MAP1LC3A,F10,KCNA3,SSBP1,PTN,TMEM31,RAB5A,PC,APOBEC3D,NEK2,ZNF526,NDUFV2,NDUFB7,GOLGA7,REP15,TMCC1,RAB14,BVES,SP4,OR4N4,ZBED4,DYNLT3,CD79B,WASL,SDC4,DLG1,P2RY11,TLR6,CD151,RPN1,KCTD9,MSX1,CHRM1,IL3,LMBRD2,MRPS33,LMO3,UGP2,EIF2S1,PRDX2,DPP4,STAT1,ZNF507,PAX6,GPR26,IL1B,FUT1,DOHH,BAP1,PLAA,RPRM,LRRC4,DRAP1,MEF2C,ARL4A,ARFGAP3,LITAF,TP53INP2,GPSM3,LAMTOR3,ZNF175,SNRPD3,ELAVL4,RPS27L,SEC61A2,STK11,COMT,TESK2,GOLPH3L,TNNT2,ANGPTL2,LY6G6C,RHCE,SEC62,FGF12,RIMKLA,EXOC1,GPX4,FKBP10,PHAX,BAALC,SLC22A12,SNAPC2,CCHCR1,RPS5,PDE9A,SLC1A1,CCDC71,CYTH1,UBN1,TPSG1,UBE2F,FOXP2,CYP17A1,ADNP,LAMTOR1,RAP2C,DDX5,EIF4A3,RNF14,GTF3C3,CSTB,MCHR2,KLHL7,DET1,OR51A4,ZNF330,RGMA,DNAJC10,RAF1,IRF6,GPNMB,SAT2,PRRG1,PHKA1,ALG2,MBLAC2,SCYL2,COG1,RPL10L,DNAJB6,ZFAND2B,KDSR,GCC1,LRRN1,CD1B,DNAJC27,ATP1A1,CRKL,TGIF2LX,STARD13,B4GALT1,AOX1,PSMA5,CNPPD1,NLRP1,RP2,STX12,FBP1,TMEM199,GZMK,TMOD1,TNFRSF14,TXNRD1,KATNAL1,GSTK1,NAE1,RPS11,GTPBP1,KCNMB2,NDUFA12,NUDT5,AZI2,ARL15,ILVBL,EGFL8,MAGOHB,COMMD2,TM9SF1,PEX5L,CBX5,MYCT1,ARL10,FAM118B,GABARAPL1,KCNMB1,TRMT1L,UCK1,CDC123,GNAI2,TRIM11,VMO1,C1QL3,MRPS18A,PROM1,QPCTL,TOPBP1,RBM18,RPL3,MTG1,G2E3,GLRA1,NRSN1,HOXB1,OR4K17,MAX,TMUB2,RHOB,YIPF4,CSNK2B,FLRT2,BOLA3,DEDD,PPM1G,CDC42EP2,E2F4,MRPL52,FCF1,PLN,CD1D,GFI1,GLYAT,TMEM209,GAPDH,YES1,GRIA1,CRYGA,CBLN3,CLIP3,SLC25A42,VAC14,HDAC5,FABP12,FGL2,PI15,HECTD3,GKAP1,UBL4A,SERPINB11,RPL17,MPST,PSMC4,ASRGL1,MFSD6,POU3F4,MADCAM1,TMEM97,MED13L,NSDHL,IDH3A,RFC5,JRKL,RLN3,ANKRD50,SLC35C1,NXT1,ESAM,HSD17B3,PCCB,NEO1,PDIA2,SNAP23,FAM76B,RNF146,SAP30L,ELOF1,GGCX,PAQR4,BOLA1,PICK1,NTRK3,TSSK1B,CCAR1,FBXO3,STX1A,AGAP2,GUK1,ACHE,UBE2B,CSE1L,IRF2BP1,NEK9,TNFSF10,FMO3,CDK5RAP3,OR4N2,MNAT1,STAC3,FAM3A,CAPZA1,CLDN6,ITGA2,SLC31A1,DIO3,COX6B1,SRSF1,LMBRD1,UCK2,CAV3,EPHA2,FGF7,MAPRE2,CDK2AP2,IGSF21,PRPF18,PIK3R1,ACOX1,FADS2,F7,IFT52,TSPAN7,SUMO1,KLHDC8A,POLD2,KDM2A,ZNF574,EXOSC8,G3BP2,OR10G3,OR2J3,DCLRE1C,CBL,LHB,INSIG2,DEFB124,WDR6,ACOT6,IL12B,HSDL1,KLHL23,COPS4,KCNK17,ZGLP1,ANGPT1,NCALD,CYP1B1,MDH1,ELK1,FAM168B,COX17,RAB28,DDI1,MRPL41,RALYL,MRAS,MRPS35,MMP14,RAB6B,ATP6V1G2,TMEM19,SLC35A5,LGI1,CDC5L,CRMP1,TCP1,KCNH8,HPS6,OR2F1,CH25H,RABIF,ADRM1,CNOT7,TAF11,PKIB,EMX1,UBTD2,IREB2,CD80,PITPNB,USP46,SMAD2,CCDC167,NGRN,DBNDD1,GIPC3,RAD1,NFE2L2,POLR2C,GNAQ,LPAR6,PPIC,MMAA,NCOA5,RUVBL2,IGF2BP1,GOSR1,SNX3,DBH,CLRN1,TBC1D5,NDN,SIKE1,ARMC6,CHCHD1,PTGDS,IL5,VDR,CTTNBP2NL,PSMB2,FGF22,CX3CL1,TNNI1,PEBP1,ADRA1A,VAMP1,COL3A1,CBX7,PAK1IP1,QSER1,SLC2A1,MYO1B,GPT,SRSF12,GPN2,TLR4,SLC6A1,ADRB2,SLC38A2,HS3ST5,PLAC9,GPR22,P2RY10,NKX6-2,TAF2,SGMS2,ANXA7,NCSTN,SSR3,LIN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PROS1,GPX3,EWSR1,B9D2,MTRF1,ZNF592,TGFB3,ACSL4,TRIM24,MRFAP1L1,CIB2,YAF2,ELP3,MRPS16,ABHD14B,EED,CREB3L4,B3GALNT1,EIF3K,CD274,FABP7,BCAP29,ZBTB17,BZW2,TSPAN5,OR10G9,RINT1,NAT2,KHDC1,SPECC1L,COX4I2,CDKN2C,LHFPL4,TRIM5,EIF4E,TMSB4X,DDX39A,RAB40AL,IGBP1,AKAP12,SSU72,BLOC1S2,SNCG,SNAPC3,IFNA10,DEFB114,MT1M,TFE3,COMMD8,ITGA6,CSNK1A1,GOLGA7B,OLFML3,TSPO2,PREPL,THTPA,SH3GLB1,RNF113A,EFNB1,IL10,UBE2V2,RPLP0,RTKN,NTN4,FUT9,PHYH,SFRP4,RGS7BP,CDKN2AIP,FCN2,RER1,MRPS23,FUNDC2,CSRNP1,ATG4A,SYP,ZNF862,POLE4,HSP90AB1,ISG20L2,GPHN,TMSB10,IPO8,ATAT1,ARMC7,CIDEB,TMEM123,ZBTB5,ZC3H7A,CCR2,AIF1L,DSTYK,NRSN2,SRRM5,TOP1,TMEM144,APOO,SNX17,BCS1L,GPR137,ZNF740,NDUFS8,CYP2C18,MYO6,GCNT3,OPRK1,NKX3-1,F9,PGPEP1,BCL7B,TOM1,SEC61B,GPR65,TCF23,PAPSS2,GBE1,CHGA,DNAJC22,EIF2B3,TMX3,HTR5A,RDH10,PDCD4,GPAM,LDOC1,CREBBP,PRPF19,HTR1F,OR4Q3,GPX6,POPDC2,GREM2,TGIF2,RPLP2,CDC42SE2,ACBD7,FAM98A,TRIM54,ACAT1,KDM4B,TMEM184B,ZNF287,RAB3D,LAMB2,SLC13A5,CLDN4,GIT2,NKIRAS1,OAS1,CXCL3,GTF2B,SDF2L1,RUVBL1,SAT1,CSGALNACT1,R3HCC1,SLC35D1,SMU1,RMI2,COL1A2,JPH4,AMIGO1,PTS,TOR2A,GTF2H2,MBL2,MAP3K11,METTL14,VAMP5,EDEM1,GNG2,UHMK1,CRTAP,LCP2,ADIPOQ,ANKRA2,ERH,ALKBH5,AKAP14,NDUFAF4,CRYBB2,FAM162A,CTDSP1,CCNB1,CLDN1,ABHD6,METTL2A,TFCP2,FMO2,TMEM177,GLIPR1,SQSTM1,RPP25,RBM12,RAN,KIAA0408,NAPG,RNF122,CREB1,SERPINA5,BICD2,GTF2F2,OR2H2,PAFAH1B2,CCL17,KIAA1191,KCNH1,BRD9,HAND2,PGR,POLR3B,CDH13,NPY5R,HSPA14,CXCR4,PXMP2,ATP1A2,MT2A,PPP1R16A,GMPPA,CYB561D2,SLC7A14,DDX42,BNIP3L,RPL6,SPRR1B,TUSC3,CXCL14,ADAMTS1,CLDN8,KLHL15,PAPOLB,PLAGL1,SESN2,TRAM1L1,RFXANK,EHD1,MPV17,CHST1,TRAM2,PPP1CB,GCA,ZNF576,RABL3,ISCA2,UPF3B,MANSC1,GJB2,WDR3,PLEKHA8,KRT7,TMEM106C,SRP14,NUS1,KCNK10,SLCO1A2,ZNF609,TMCC2,APLN,TMEM164,ACP6,SYNJ2BP,ACTR2,TAS2R5,FOXS1,PTRH2,OR4F6,CRYBB3,CD47,HIRA,S100A8,IFNG,JUN,TMEM50B,WWP1,RHOJ,CBLN4,PTGER1,RAB23,CMAS,SFT2D2,ZNF687,OGG1,CCR3,SUMO3,OPHN1,FAM107A,RNF167,CRYGD,RAB33A,DNAJC8,PPDPF,TNFSF18,RNASEL,CHI3L1,UTP23,GNPNAT1,GIMAP2,TOMM40L,EIF3J,FERMT2,SPTBN1,TNRC6C,SCD5,MAFG,ACAP2,LHFPL2,PRKAG1,PAFAH1B3,HNRNPK,NFKB1,OS9,RPL26,POMP,OAT,RIOK2,MRPS28,FOS,DYRK2,EGLN3,CLDN22,PPID,YPEL5,CCL8,SLC35E1,CAPZA2,RB1CC1,TPPP,RFTN2,PLA2G15,OR2A25,STX6,FANCG,ATP6V1C1,GGCT,RCBTB1,HNRNPA2B1,TAPBP,ZFP1,PDYN,B4GALT3,VPS33A,SACM1L,CD226,CRBN,CCNF,VAMP2,TRAPPC6B,GPIHBP1,WDR44,RAB2A,CTNNA1,CMPK1,SNRPA,BEND5,ACADSB,SNX24,ISG15,OR10G7,STAT6,PHYHIP,DYRK1B,WIF1,FN3KRP,AMT,RAB9B,ARCN1,EZH2,INPP4A,KCNIP3,LYNX1,RPL23A,IL6ST,TMEM59,DERL2,TXNL1,TIMP1,PLEKHJ1,MLF2,ELMOD1,PPP2R1A,SMAD3,SLC25A4,PTHLH,MRTO4,EIF4B,WEE2,PCDH19,RAB5C,PNP,AP1AR,STK38,TIMM10,C1QL1,FBXO25,PSRC1,IFI35,CSTF2T,CAV2,FOLR1,RAB37,SLC6A11,SLC23A2,GYS1,PGM2L1,ROGDI,SOS2,PIWIL2,AKIP1,MED11,CLIC2,SDHAF2,PPFIA3,OTUD7B,CDKN1A,GK2,RBFOX2,FOXN2,STX18,ORAI3,ELSPBP1,SLITRK2,CD2BP2,TDRD7,HMBS,LDHAL6B,CCDC65,AMY2B,RBMX2,NDE1,RAB1B,OR5L1,RGS5,RPAP2,INHA,ZBTB45,ABHD13,HRH3,SNIP1,SLC4A8,LY6G5C,UBE2D1,ACTL6B,FAM168A,TEX12,HIGD2A,B3GNT2,TOP3B,ZCCHC9,SLC43A2,TMEM91,DDX4,CAB39,LIX1,KLK5,GRIA2,LRRC24,MRGPRX2,CDH8,CPSF2,GDE1,TCEAL7,TMEM14A,GPX5,PCGF3,MOV10,GLT8D1,UQCR11,NGB,PNPLA8,MYEF2,TAF5L,PRCC,GSK3A,SLC20A2,PCDHA5,UBXN10,LDHA,PFDN6,NUBP2,RC3H2,FATE1,ATP2C1,DNAL4,ABCC5,THOC1,NUDT19,RANGRF,CREB3,RNF103,TF,SURF4,INTS10,XPO5,XPO1,EXOC2,GJA10,EFHC1,SLC25A32,THRAP3,EEF2,ZNF513,SLC7A4,ZMYND11,RNF187,GPR162,APOBEC3C,CIRBP,ANKIB1,ENDOD1,CXXC5,GALE,SH3GLB2,EIF2B5,GTF2A1,WBP2,FUT8,MOB3C,LASP1,PHKG1,SPOCK1,NEK7,UTS2R,GNMT,CCL25,CREBL2,TXNIP,AQP4,SLC39A9,DHX9,FURIN,PSMD6,IL23A,WDR37,EIF4EBP3,OR51S1,ZSCAN1,LEPR,STX17,WNT7A,PDIA3,FRA10AC1,XPOT,CXCL1,ISYNA1,NDUFB8,APH1A,EIF1AD,NAA11,NLE1,KRR1,PELI3,CDC37L1,SNAI3,MSX2,RPRML,RPL37A,SERPINH1,PGBD2,SIPA1L1,STAMBPL1,CLDN14,ZKSCAN1,HSPE1,LHFPL1,B4GALT6,KCNA2,HSPB1,GXYLT1,OR6M1,NUDT16,RAB4A,SOX21,TRA2B,DHX16,LEAP2,HADHA,IGFBP4,LMBR1L,AKR1C2,NPVF,OPA3,TAC1,TBCE,SPATA2L,IPP,NQO1,PAOX,BRMS1,CD3G,CHRNA7,GAS8,KIF1C,CDKL2,BRI3,OCEL1,ADAT1,HEXA,TMED1,RBM23,OXNAD1,NDUFA5,CCL21,KCND2,HBB,FGF17,CXCR1,NEDD8,PTCRA,TRMT6,CD2,POLR2I,TIGD7,FBXO30,RABAC1,WWP2,ACAA2,RAP1A,UCKL1,IL34,DFFA,RASGRP2,LPXN,ST13,DUOXA2,MTMR12,MMACHC,TRAF7,TNFAIP3,ABHD16B,RAP2B,ETV6,RRAGA,TAPBPL,IQSEC1,NOL4,FYTTD1,SIRT7,NONO,POLL,TSSC4,MAK16,ALDH1L1,H19,SPRED1,NDUFAF2,GPR37L1,SNTA1,SNAPC1,GFOD1,SIVA1,EIF4EBP2,OR2A2,HPCA,SV2B,ZNF805,TCP11L1,SOST,NAB1,ENPEP,PROX1,PRKX,FGF13,RTP4,LSM6,SYNGR1,USP38,ZNF174,USP39,CERK,SLPI,SNRPD2,ADCY3,CDK6,CWF19L1,DCAF5,ESR2,SOCS2,INTS12,CYP2D6,CTNNB1,RAB8B,CLEC12B,SFTPD,TGFB1I1,DUSP1,BATF,TOLLIP,STX8,S100A10,FAM200A,NFYA,URM1,CETN3,CTSK,CACYBP,RAB3C,MTAP,PWP2,NDNF,DCAF8L2,CPT2,CHST9,ANP32B,FBXO9,COX7A1,WFDC13,ACOT13,TMED3,OR2W1,RPGRIP1L,CCND1,SETD4,LCN6,ARHGAP21,SCG2,RHCG,BMPR1A,FAF2,KLF10,S100PBP,MRPL47,TMEM33,MPHOSPH10,AP3S2,MIA2,BACH1,KIF2A,INPPL1,CRYBA2,DEGS1,ARMC8,ENTPD4,SLC35A2,PTDSS1,ID1,POU1F1,CYC1,CCDC42,FCAR,NPTN,CD164,BPGM,CDKN3,PPIB,NLGN2,DEK,SLC5A6,PRKD3,CYP4F8,SPEF1,OR52M1,NUP107,SCAMP2,MRGPRX4,FABP5,CTSD,PGAP2,MRPS25,RBCK1,NFE2L1,AKR1A1,NOP58,SPATS2L,EHBP1,MDM2,MGP,MRPL13,PSMA3,CCDC69,GALNT1,SOCS5,AK2,TMEM156,GSTO1,B9D1,NUDT3,CNP,RND3,EXOC8,PFDN5,UST,GNRHR2,TOM1L2,LYAR,CDO1,PPIL4,RAB11A,CCNI,ASMT,SF3B4,IL20RB,DKK3,CRABP2,DPP10,PRRC2A,DLX1,AKT1,APEH,FGD2,FNDC8,COMTD1,TLR9,L1CAM,SNX20,FIBIN,C1QC,TRIM3,TMUB1,POLR3H,ZNF207,EDF1,ATP6V0B,TMEM219,RPS14,LIG3,LYPLA1,MEAF6,UGCG,ZNF671,SLC25A31,SLC17A5,TRIM32,CD99L2,PRIM2,SNRNP27,PDIA6,SDR42E1,UBR7,PLA2G5,KLK9,DOK4,ARHGAP1,RNF141,KLHDC8B,GFM2,GDI2,MRPL23,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,E2F6,NHP2,NAIF1,TRIM23,OR8B8,IRF1,ING1,STRBP,P2RY1,ARMCX1,UBE2A,CCT2,UBE2D3,ATP6V0E1,ELMO1,TCP11L2,GRPEL1,PRPSAP1,GABARAP,FGFR1OP2,CASK,OR4D11,GAL3ST1,LTBR,LMO4,KIAA0232,ATPAF2,CLU,CDK5R1,NCKAP1,NRP1,CNIH4,GLUL,XAGE5,APOBEC3A,ZNF397,ID4,ZNF319,SEC14L1,CCR6,TAAR1,SLAMF9,ZMYND19,GPAA1,JAKMIP1,ADGB,TLR3,CYP11B1,CTNNBL1,GRM2,IDH3B,SENP5,GNRH2,CHDH,EIF4H,ITK,NCR3,FAM8A1,SWAP70,CYP39A1,HSD11B1,MYL12A,SLC30A5,KLK3,SNAPIN,ZNF304,MRPL50,MRPL24,DHRS4,SLC35A1,IMMP2L,RAG1,ENY2,MIOS,PPP1R2,FAM78A,RMND1,OSM,IL15RA,SLC38A9,AAMP,MX2,GPBP1L1,SYN3,ZCCHC10,MFSD6L,LYG2,ATP6V1G1,MTPN,WDR77,FZD4,MEST,TSEN54,SERPINB10,ZNF24,TMEM215,FBXO42,JAK1,LBH,MLF1,GTF2E2,MAGOH,CCL19,TBC1D10C,NKX3-2,AZIN1,PSME2,AZGP1,HBE1,ABCB1,INO80C,FGF1,KTI12,SMAP2,RAB3B,CDCA3,DHRS3,TNFAIP8L2,DEFB116,NDST1,ATF4,CTNNBIP1,GNG7,KBTBD2,GSTO2,KPNA1,PIWIL4,CSNK2A1,RARRES2,OR4D9,AFTPH,LSM3,RS1,KIT,SUPT7L,JOSD1,P4HA2,BTF3,MMP9,LHX2,ZYX,UBAP1,CDC73,CYP27A1,S100A6,DYNC1I2,DNAJC5,TMIGD1,VRK1,ROPN1B,PGK1,HEBP1,PACSIN3,SLC7A9,ALKBH4,SNAP91,MYH2,RPL15,TUBG1,GHITM,TTC4,SCFD1,CCDC47,CAMK2G,SRP54,BUD31,TMX4,TACR3,CIB3,PRMT2,PPP3CA,CRYGB,KCNJ11,CD200R1,CCDC127,RCVRN,FAM89B,PEX3,SHC1,OR4K1,PYGM,FGFR1,CAMK2N1,HCRT,AGK,ANAPC2,FBXO32,SORD,SBK2,MCOLN1,PSMB5,ENPP4,CCT5,RAB18,IDH2,FKBP14,CD58,AGER,IMPACT,PRPF4,ARMCX5,ZNF593,PGS1,RBBP7,SLC25A21,RMND5B,SETD5,HNRNPC,PTPN1,ZBTB38,HECW1,TRIM37,NFIL3,PPARG,GALNT12,ARFIP1,SPR,ARMCX2,ACTA2,SIX5,TRIM21,PCDHB8,RBM17,HEY2,FRMD8,RFX4,ZDHHC14,PKNOX1,ADRB1,NPY2R,LRP12,RNASET2,SLC35E3,SPTAN1,TRAPPC1,NIPA2,PAEP,RABL2B,CLDN11,FAM199X,COX11,CLIC4,NPTX1,HMOX2,HNRNPH2,ADM2,ALDH1A3,AHCYL1,IZUMO4,TESK1,DVL2,TMEM108,BRD3,SURF6,FAR2,TTC33,C2CD4C,OR2AT4,RPL39,UCHL3,EEF1A1,TRAPPC4,GAS2,WRAP53,MAP3K21,MMD,KLHL26,BET1L,PRKCA,TFPI,PAAF1,TST,RNF5,DGCR8,RPL9,API5,SPRYD4,KCNS1,TPH2,SAMHD1,CRYM,ZMAT2,DOLK,NT5C2,EHD3,MRPS18B,ST3GAL4,P2RY12,DNAJC30,FKBP1A,SRXN1,ENC1,KCNJ8,SAMM50,FOXP1,SLC4A10,HOMER1,PSMB9,PDE8A,TRIM6,PYGB,ALPL,SLC20A1,RCCD1,EXTL2,EFHD1,C2CD2,ADIPOR2,LAP3,ABCB9,FAS,ATF1,RBBP4,COX6A2,POLR3GL,UBTD1,MAD2L2,TMPO,ARMCX3,OR5A2,COX16,CUL3,CCDC92,AKT3,POLD4,MAN1A2,ERVFRD-1,EIF3D,DNAJC4,RBP5,CHMP2B,ELOVL4,PAK6,GRB10,CSNK1E,SKA1,PI16,BHLHE40,MAP1S,GLRA2,RPL29,MRPL53,HDAC3,ARPP19,GDPD3,ANAPC4,FABP4,COX4I1,MPHOSPH6,TOMM40,GREM1,LRRC4B,SDC2,CTDSP2,RPL10A,FAH,CAMSAP2,ACVR1B,ACTR1A,LAT2,FITM1,SNX14,AIFM1,POLR2G,COQ10B,RAD21,RAP1B,AKAP17A,DNAJB4,TXNRD2,C2CD2L,TIMM8A,NPC1L1,KLHL9,CARHSP1,MCMBP,APBB3,SEMA5A,AGTRAP,CRADD,PPP1R3C,KCNAB1,TMEM11,TNFAIP1,S1PR4,CNOT6,CHPF,REEP6,MATR3,LAMP3,DNAJC2,GNB1L,ATP1B3,ZNF473,SELL,KIAA1143,GNL1,ROMO1,CRYAB,PPY,TAF7,APOC4,CYTH2,RNF11,SYNGR2,NAB2,FXYD6,ZBTB25,CD28,WDR82,TLR10,OR4S2,OXCT1,ENO2,PSENEN,SLC2A8,CD86,PNMA5,MANBAL,FARSA,UBE2H,KBTBD6,ZNF704,G6PC3,RANBP6,SLC25A39,CD14,PRR5L,CYP2R1,GOSR2,SLCO1B3,FGF23,SFRP1,WSCD1,ELF1,TMX2,HTR1A,ZC3H11A,CCL27,KDELR2,DAP,DDX1,RNF40,RPS26,TP53I3,RNASE6,DPM2,BRIX1,IRGQ,CFL1,KLHL3,HEBP2,SP2,VAPB,PNMA1,CALML5,TCF21,CASC3,SLC6A3,TUSC2,SEC23A,MYL6,TIRAP,GEMIN8,RPS9,TOP2B,PSMG3,GPR173,OR5V1,PPP1R8,SHISA2,MAB21L1,RAB35,KCTD10,MKLN1,CCL28,CMTM6,VPS26A,EEF1E1,FEM1A,CD40LG,TMEM50A,SMG8,LILRB4,MYC,IL2RG,PIWIL3,ALB,CCM2,PSEN2,SLC35F1,SNX1,FTH1,SLC25A26,SYK,VPS16,ACO2,CLN8,BACE1,DUSP10,SLC38A1,SLC48A1,CDC42,TNFAIP8L3,MORF4L1,TMEM174,NLGN1,PCBD1,TTC23,AGR2,CACNB3,AGA,CD63,LCN8,CPSF4,PARM1,DNAJC24,AKAP1,CLEC1A,KBTBD3,PCSK9,PSMA6,OSGIN2,NECAP1,GPC4,MZT2B,LIMS2,HBA1,GADD45B,STX7,SENP8,MGST2,PPM1B,PKIA,TRIM35,TRAFD1,INMT,NFKBIL1,CRELD1,TP53,KIN,AP2M1,TAX1BP1,PRDX6,HSD17B1,HEXIM2,TMED4,TBC1D17,SLC25A46,FCER1G,BET1,CYB561,IRF8,RWDD4,KPNA6,TOX,PTRHD1,SYNDIG1,GSTM3,FTSJ3,TSEN34,SETD7,PPIF,DUSP6,MTHFS,DAG1,ZBED3,CYB5D2,RPS12,MAF1,TXN,ARF4,GABPB1,CALY,RDH12,TAX1BP3,ZNF790,PSMA4,DNASE1L1,GABARAPL2,PML,EIF1B,MT3,SERTAD3,OR10A7,GNPTG,ENO1,OLFM2,RPL24,CRYL1,SERPIND1,CHST7,ORAI2,SLC25A14,PRDX4,NUP35,MECP2,ZNHIT1,TFPT,ELOVL6,ALOX5AP,RGS6,CSTA,CLSTN3,TBC1D19,RASL11A,LYPLA2,TSPO,DCAF4L2,RPRD1B,RNF181,POP7,STYK1,CYP11B2,FBXL7,LBR,CELA3B,OMG,GPD2,RHBDL3,TRMT61A,CAMP,COX5A,THNSL1,SLC1A2,PHF21A,SAR1B,CCR5,CAPG,OGDHL,TLR1,IL12A,RHAG,PAPOLA,DHRS1,HCST,FBXO34,BRMS1L,OR5B3,ZBTB16,ANAPC16,CHORDC1,EBLN2,NAA15,SYBU,EXOC5,SERPINB6,ADK,G6PD,F11R,FTHL17,WDR55,RALA,TLR7,GAPT,VASH1,PPP2R5A,RNF128,PTGES,ACADS,ARPC2,CLEC7A,APPBP2,GPR146,OPTN,KCTD11,ENHO,GINS3,MYL12B,PID1,NECAP2,SRSF4,EXOSC3,SH3BGRL,IL7,ATP6V1E2,ZHX3,SDCBP,USP13,TMEM42,SNX33,NDP,CEP85,ERLEC1,SRPRB,FGF3,DRG1,SNX12,POLR2D,PDP2,SMNDC1,NEURL2,CNTFR,KRT222,HHIP,LUC7L3,MAP4,LGALS3,NMBR,CTNND1,KPNA2,FAM91A1,LCN12,SMYD3,DDIT4,RAB3A,CA8,OR10Q1,YIF1A,OR1F1,RPS3,LRRC20,EGR2,HAX1,CALU,AIF1,HBEGF,CHN2,TMEM60,USP30,UFM1,RAD23B,FOXJ3,ORMDL3,KCTD12,UQCRQ,RPL12,CD83,DNAJC7,ICAM1,PLCL1,MTMR2,YWHAH,MRPL49,FAM187B,GABRB3,GFOD2,ADAMTS20,DUSP22,SOD3,LSM2,PABPC1L,CCT8,TMBIM6,FOXI3,UTP6,OR1S1,SH2D5,HMGA1,GGPS1,MND1,TSPAN11,IPCEF1,ZNF267,IDE,TFRC,TTC8,AUH,C1QTNF1,HSD17B11,ZNF177,ZNF652,SPSB1,RBBP9,FBXO11,DGCR6L,WNT10B,ETFB,VIP,LRRC8D,NTNG2,ACTR3B,ZNF22,TFDP2,C1D,ZNF189,EEF1B2,RBM15B,MIF,HRH2,AP2A1,APTX,TMEM45B,BCL2A1,ZNF688,SPINT2,KDELR1,TOM1L1,RRM1,RBM22,RPS16,KRAS,OXSR1,ORC5,ILF2,BAG3,ZNF365,PSMB1,CRIP1,ZMYM3,ASNSD1,CNTN2,NR2F6,DKK1,HERC4,NDUFAF3,CHPF2,IER2,RASD1,CCS,NLRP3,ILDR1,SHISAL2B,SCGB1D1,RND2,PPP1R1B,BMPR2,COMMD3,SCG3,OLFM3,MFSD5,FGFBP1,MRPL18,METTL21A,POP5,PSORS1C2,G3BP1,CHAC2,PCDHB13,RPS27A,DSTN,DAPK3,DBT,ELOVL7,RAPGEF5,TPD52,TMEM101,NUF2,OR13C8,HINT2,SLC16A1,CHIC2,CHCHD4,SUFU,MTA2,CCDC86,MRGPRX3,LAPTM4A,FBXL19,KCNC1,OXTR,SLC38A7,PGGT1B,OR2Y1,STX11,SERPINA1,PMP22,LARP4B,ANKRD34B,LSM10,HSPA13,NPSR1,LMAN1,PPP2R5E,SLC11A2,SH2D1A,SCLT1,MRPL11,DAAM1,LRRTM3,NPPC,PSMD4,RPS7,GRAP2,RAB27A,GPX1,RELL2,TRIM15,FBXL14,RHEB,DHX15,OVOL1,DDX46,PDHB,ZNF664,MLC1,MAT2B,OCRL,XCL1,BBS5,GANAB,RPS6KA4,TSPAN18,SLC6A6,SLC30A7,TCF19,CCDC134,AFAP1L2,TMEM30A,B3GALT1,KCNJ3,COMMD6,GNPDA1,IRAK4,IMP3,UBL3,NCDN,CYP21A2,GNAO1,MRPL34,NDUFB6,TMEM117,SNX22,SFXN2,FASTKD5,CST11,SRSF7,EPCAM,PCDH17,SAV1,TAGLN3,STAT2,IL22,PRR3,GLRX,TOR3A,CBLL1,UBA3,BFAR,TOMM22,TMEM179B,HENMT1,CSTF3,RPL7L1,CSGALNACT2,ST6GAL1,FBXW11,CINP,CNDP2,PPFIA2,OR4D6,THBD,BCL7C,IL1A,TYW5,NUDT12,CBLN2,RPL27A,HTRA2,NDUFAB1,JAGN1,SNAP29,PTK7,DHX38,GPR171,COX8A,LGALS8,TMEM147,USP8,NEUROD2,METTL15,PGRMC1,CHST2,HNRNPA0,IKZF5,CD247,FZD3,RHOBTB1,NXT2,NDUFS6,TMEM126B,CTSC,CDAN1,OPRM1,SPRED2,DDX23,PCNA,PDE1B,PIK3R2,CREG2,PCYOX1L,PLD3,AGPAT5,DNTTIP1,HR,LRRC3,ARPC3,DKC1,FBXO44,GNG10,SMG9,MUL1,NRN1,MAPRE1,CTXN1,SEC22C,METAP2,MME,ZFAND2A,APOBEC3G,NTRK2,PABPC1,GNG12,OR10A4,ELMOD2,USP15,LPAR2,FKRP,CNRIP1,SIAE,ISX,GAMT,GLRX5,RTN4,GNAZ,ARG2,DNAJB9,RNF144B,ADAM21,CLDN3,MGAT5B,PTAR1,THAP7,UAP1,RLIM,PTEN,INO80E,DEPDC1B,CRLF3,UCN,CENPW,FRRS1,SNRNP48,ATG4C,GFPT1,SDHB,TXNDC12,RWDD3,EPHX1,CXCL13,ABHD5,CKS2,RORB,NEGR1,FDFT1,SIT1,CCDC160,RPA3,MOXD1,TSNAX,POLR2B,LRRC61,UBIAD1,GTDC1,PARL,DHRS13,UBE2W,GPM6B,REG1B,FBXO22,RFC3,SLC7A8,ATP6V1A,EGFL7,TMEM59L,HLF,ACP5,SERPINC1,OR10A6,OR4D2,KLF4,COPS7B,DENND2D,ACBD6,RNF34,ATG7,TUSC1,NFKBIA,NPW,PREB,PRDX1,FAM53B,TAF10,LRRC8B,ETF1,TRIM68,PFDN2,TCEAL1,LTB,USP16,TMED5,HARBI1,SLC25A12,HMGCS1,CLCN6,AK3,PSMA1,RPL32,DDRGK1,HDHD3,SHOC2,DRGX,DTWD1,NCBP2,ASTN1,SOD1,ATXN10,TBC1D13,SMPD2,CCR1,REN,FAF1,VEGFA,TP53INP1,IQCK,AVL9,DECR2,PTPN11,SOBP,NOTCH2,NAPA,CRAT,TM4SF19,GNPDA2,TMOD2,CSH1,BTN2A2,UBL5,IFNB1,KIAA0513,SEMG2,CCNH,UBASH3B,POLA2,POLB,MNS1,KANSL3,TOR1B,SPSB3,MRPS9,LTA,ABCG2,FAM83C,MTF1,RPL27,PPP1R1A,MSTN,RNF148,PRICKLE2,CLDN9,DIO1,SLC16A10,VGLL2,SLC35F2,SYNCRIP,TRMT112,DDX50,RPRD1A,GTF2H5,CTXN2,HINT3,SLC25A10,VRTN,STK4,PPP2R2C,BST2,PLS3,CYP1A1,ST8SIA5,TNKS,SLC22A17,IL1R2,TMEM41A,FAM181B,NKIRAS2,ACVR1C,PIP4K2C,STUB1,KLF9,AVPR1B,ST7,TRAK2,SERPINB1,SRSF2,GSTA1,UBLCP1,SNRK,TEX264,GSTP1,LLPH,CCL2,OR8B12,PPM1K,AR,IFI6,LAMP2,RNASE1,TMEM45A,NLRP9,FAM43A,OR10P1,RIT1,GPX7,CHRNB2,PTPN4,EFNA3,TPM3,SNRPB,SSR2,ELOVL1,MORC2,SOSTDC1,FPGT,LRRC3B,OTX2,MAGEH1,EIF4A2,FEZ1,PRDM4,COPS5,STAT5A,TMEM167B,HSD17B6,MAP2K1,PLCB2,APOBEC3F,RNF8,PEA15,ADAMTS10,MRPL20,EP300,PRMT6,PMM2,TTL,TMEM70,VAMP8,MPDU1,TIMP3,PPP3R2,PRSS12,KLHL24,GABPA,FKBP8,PPP2CB,ZNRF1,CHST13,CLEC18A,AQP2,SMAD1,PPAN,IL2RA,SF3B5,RCL1,FBXO7,RABGGTB,SLC2A3,SEMA4C,VAMP7,CTTN,STOM,RPL23,CLLU1,SPIN3,TGFBR2,CEBPG,CDNF,TNFRSF1B,CYP2C8,METTL22,ASZ1,CAPN1,USP3,STARD4,THOC2,ORC6,FLOT1,DROSHA,NR2E1,MCM4,SCNM1,DCTD,FAM177A1,IGF1R,SLCO2B1,CX3CR1,PDAP1,SOX14,CEP19,CHMP4C,KLHL22,MAVS,UBP1,CD1C,UMPS,CDCA7L,MRPL22,SS18,EPS8,RFXAP,UPK1A,HOXC4,CHCHD6,SIAH2,POLR1B,CER1,NUDT7,IFIH1,FCGR2B,BIRC2,MTM1,SCML2,DNAJC19,VGLL4,CHKB,CCNY,ELF5,CLDN12,GPR176,PKP4,CRHBP,CNOT2,OTOS,GSTM5,ERAS,PLEKHO1,MYBL2,ZNF326,PRKACB,ASB7,GLRX2,LANCL2,APOBEC3H,ODAM,FEN1,CLPB,VDAC1,KLF1,ADD1,CBR3,SEPHS2,CLEC2B |
| 6.246e-16 | -35.01 | RPL11 (ribosomal protein L11) | protein interactions | 6135 | 614 | 264 | 19454 | 5460 |
AHSA1,LYZ,RSBN1L,RPL23,DICER1,HSPB8,ATG7,NOP58,RPL7,PPIA,RPL8,RPL9,FOLR1,PHB1,HP1BP3,RPLP1,COPS2,RPLP2,EZH2,CHMP4C,RPS11,ARFGAP1,B3GNT2,MAK16,RPL29,UFM1,RBBP7,TNF,G3BP1,EMC8,TRIM37,RPS27A,SSRP1,RAD21,SLC25A5,RPS24,SRSF7,BRCA1,DCAF4,RPS5,RIT1,ACO2,CUL3,RAB11A,NOP16,CUL2,ZNF668,IP6K1,RPF1,RPL35,RPL7L1,MAD2L2,RPL19,FAU,EIF3K,RSRC1,RPL37A,RPS9,SEC61B,EMC9,PRDX3,DET1,GPC1,NOP53,CSRP1,G3BP2,CCDC86,MPHOSPH10,MOV10,EMC4,HDAC6,RPL35A,PRNP,MDM2,ZBTB2,MRPL24,RPL12,EFNA3,RCHY1,KRR1,LLPH,ILF2,SRP72,FBP1,EEF1A1,MAP1LC3B,TAF1D,RPL15,FCF1,PAK1IP1,VRK1,THRAP3,RPS13,EIF3E,NKRF,TCOF1,RPL23A,IGF1R,CDC73,PAIP2,RPL26,FBXO7,PPP1CC,TUFM,USP14,KPNA6,NDN,ZNF622,RPL13A,RPL22,CCNF,PELP1,METAP2,GSK3A,PRKRA,UBE2I,RPS20,RPS12,LMNA,DCTN4,ZCCHC17,METTL14,RPL26L1,RPLP0,ZNF574,ATG16L1,RPS14,CDK7,NPM3,HMGB1,RPL4,FBXW7,UTP23,AATF,BRIX1,RPA3,MTDH,AGR2,DDX50,RPL6,WWP2,CTNNB1,NGDN,DDRGK1,NT5C2,RPS10,LYAR,SIN3A,EED,TUBB4B,GLE1,RAB4A,RPS23,RPL18,TRMT1L,SOX2,TUBA1A,TNPO2,EEF2,MSX2,RPS7,KRAS,H1-6,RPS4X,RPL28,RPL31,PABPC1,FTSJ3,H1-10,ATG3,RPS26,ICAM1,POLR1B,NSA2,MYC,RPL39,BTF3,PSMD4,CAVIN2,ZCCHC7,RPL10,KBTBD6,ZNHIT6,SURF2,CMTR1,SMU1,NUFIP2,PIH1D1,TRMT112,TOMM22,MTF1,RPL27A,PAFAH1B1,MRPL12,UFL1,STAU1,MRPS7,RPS28,YAF2,RPL24,SNRNP70,NOL12,RPS2,RPL10A,ENY2,HP,CD81,COPS5,API5,RPS16,CAND1,FZR1,SPPL3,RPS27L,DKC1,SURF6,CDC5L,SSBP1,RPL32,TFCP2,RBM34,DNAJC2,UBL4A,IMP3,RPSA,TP53,NEDD8,IMP4,MEPCE,RPL17,SNIP1,MAP1B,RPL3,DHX9,SPOP,RC3H2,PDCD4,UBE2H,RPF2,RPL7A,SUB1,RPL10L,SRPK2,RSL24D1,PSPC1,RPS3,RBMX2,MACROH2A1,RPA2,SSR1,WWP1,HEXIM1,ZNF770,PLP2,CFTR,RPS15,HSPA5,RPL27,BAP1,SNAPC1,NLE1,PML,HSPB2,RNF113A |
| 6.246e-16 | -35.01 | cellular localization | biological process | GO:0051641 | 2660 | 961 | 18204 | 5365 |
ZFAND2A,NEDD8,LRWD1,PPFIA2,OSBP,LCA5,HYCC1,FBLN5,EMC4,JAGN1,RAB29,KXD1,VAMP8,RAB1B,DHX9,RABL3,NAPG,CMTM6,GAS8,ATP6V1C1,TOMM22,RAB3B,TVP23B,PPY,SLC31A1,MCM8,C9orf72,ADRB2,THOC3,ISG15,SLMAP,PRPF19,OS9,COPZ2,CSE1L,WDR11,SLC66A2,RABL2B,VIPAS39,SKA3,JAKMIP1,SYNGR1,HGS,RAB28,BAG3,SOX9,NDFIP1,CBL,VTA1,RAB13,EMC1,DLG3,RAB3A,KIF1C,DLG1,TRAPPC3,BECN1,TOPORS,FIS1,POLA2,CBLN1,NAPA,DDX42,RAB4A,ABCB9,UBAC2,ZDHHC15,KCNB1,FCHSD2,CDC42,FTH1,SLC6A2,FERMT2,IFT172,CSNK1E,GOSR2,ARFIP1,SCG2,RAB9A,YWHAH,ID1,RAB18,CCL3,HNF1B,NXT1,SLC48A1,C1QL2,STK3,CFL1,ATP6V1D,UNC119B,STX8,MAVS,COG1,VTI1B,SEPTIN7,AP2M1,RUVBL2,IFT22,MDC1,OPHN1,HSPA5,TULP3,CD81,AQP3,CCDC186,TBCCD1,PPT1,RANBP6,ACTB,VAPB,TNF,GRPEL2,RPA2,ERLEC1,ING1,SEC13,ANP32A,TESPA1,BCL6,ARL4D,RAB11B,CTDSPL2,NSFL1C,TOPBP1,GOLPH3L,CDK5,FGF7,SEC22A,RANGRF,SNX22,CHRDL1,SSR3,TBC1D24,HINFP,TMSB4X,CDKN1A,MDFI,TOMM20,RAB37,GPR89A,RSRC1,TBC1D10C,IK,CITED1,NUP35,RB1,TMEM107,TRAPPC6A,RAB31,EXOC3,GJA1,RP2,SEC61A1,YWHAB,CASC3,ARF6,H1-5,STK4,TP53,MAP1S,SPCS3,SDCBP,PPFIA3,MDM2,SSR2,NCBP2,SSR1,EHD1,KIF3B,SYNJ2BP,SKA1,SNX20,LARGE1,HSPA8,SLC15A1,ANO3,ARHGAP1,TRAM1,TMEM38B,ARF4,NUP42,RPS15,CER1,DLG4,RPAIN,ZBED3,HOMER1,TMEM147,TMED7,TOR1B,CDAN1,RAB3C,SNX2,SAMM50,KPNA2,IPO8,HEXB,GPHN,FAF1,MAPRE1,HOMER3,SUFU,CHMP5,FYTTD1,MLC1,CDKN1B,CD3G,SGTA,BET1,RBM15B,CHMP4C,SCFD1,SLC15A2,SNX18,NSG1,CALR,ATP6V1G2,NFKBIA,ROMO1,SLC18B1,ENY2,KICS2,TNFAIP3,DYNC1I2,NUDCD3,RAB3D,TXN,BAK1,MAP1B,AIFM1,AKT1,ARFGAP1,SLC6A1,PPP3CA,WNT7A,VPS39,FKRP,TSPAN10,TMED4,FUBP3,NRP1,PCSK9,TFG,PIP5K1A,TSG101,SYVN1,PRKCE,TMEM88,CPLX2,KIT,FHIP1B,TSPAN5,CYB5R4,XBP1,BUB3,CPE,TOLLIP,SOD1,SYNRG,LHFPL4,LMBRD1,LAT2,PAK2,ZDHHC14,ARL11,SLC6A12,KPNA1,DDX1,MACIR,IMMP2L,RAB23,THOC6,GPM6B,LRRTM1,DNAJC27,BORCS6,BBS5,G3BP2,ACVR1C,CEP19,CETN2,ASPM,CHMP1A,DDX39B,HEXA,RTP4,BAX,TRAF3IP2,EIF4E,EFCAB7,LAMP2,AHCYL1,ID4,TOM1L1,TMED1,ERRFI1,AKT2,VPS26B,EMC10,FAM149B1,MIA2,SPRY1,MIR130B,CLIP3,SNAP29,LMNB1,SAR1B,PEX5L,TXNIP,EDNRA,SMYD3,XPOT,PAX6,TP53INP2,SCAMP2,PRKAG1,TRAPPC3L,OPTN,VPS18,PIGW,CHMP2B,ZBTB16,MCL1,ATG7,KCNIP3,LEPROTL1,HDAC3,FAM53C,TIMM17A,TNIK,PPP1R10,HM13,DSN1,EHD4,AQP11,SYT4,SFN,DNAJB6,XPO1,SCN3B,ODR4,SCYL2,CD2,SPTBN1,UBAP1,NPC2,LAMP3,YKT6,RAB33B,TIMM13,STAR,LACRT,NUP37,ASIC1,VMP1,SCG5,NUF2,DERL2,ARFGEF1,RAB14,SYK,TMED9,STX11,STK11,STX16,SELENOT,ZC3H11A,LIN7B,TESC,S100A8,SGF29,ZDHHC17,HDAC6,EHD3,EXOC2,ARL2BP,ARL6,NUP62,WBP2,CBLN4,TUBB,TRAM1L1,NHERF1,SYP,TIMM8B,DRD1,RAB5A,USE1,GLRB,PRPF31,SNAP23,STX6,RNF26,XRCC5,VIP,NPTX1,YIPF5,PICK1,VAMP3,TRMT10B,VPS54,CDC23,NLGN1,RAB22A,NUP107,IFT52,PAFAH1B1,CACNB2,TIAM1,ARFGAP3,SYT2,ZFAND2B,PHAX,MAGOHB,STX10,ROCK1,THOC1,P2RY12,GPIHBP1,NEO1,SURF4,STAU1,WRAP53,OLFM2,LAMTOR3,CHTOP,NDE1,TRAPPC2L,HNRNPA2B1,NECTIN2,STX18,THY1,SLC6A11,PIK3CG,INSIG2,PARP11,HIKESHI,UTP25,AP2S1,EMC8,SEC62,LAMTOR2,SNX24,PRRT1,CTSA,BORCS7,CPLX1,MIR301B,TERB2,YWHAZ,CCDC47,WDR19,MTX2,ACAP2,PIK3R1,RAN,SRP72,AGK,CUL3,NR0B1,PIK3R2,GORASP2,CCNB1,CAMK1,BICD2,BET1L,TIMM21,STX17,CHP1,RIMS4,SLC6A3,KLHL12,DPY30,STBD1,CPT2,EMC2,CPT1B,FGF10,SPC24,SEC22B,ATP6V1G1,EIF2D,PEX13,HSBP1,TRIM37,TMEM115,WASL,TOM1L2,ZDHHC24,AP5S1,VPS4B,SNX33,TIMM10,CDH13,ACTN4,XPO5,RIT2,MACROH2A1,TTC8,HPS6,RER1,H2BC11,EDEM1,MAD2L1,COPS5,SUMO1,RNF126,RAP1B,AFTPH,CTBP1,PRKCB,CHGA,CTNNA1,ARL5B,AP5M1,AIP,PICALM,HYCC2,ATP1B1,TMEM50B,SEC61G,THOC2,CLBA1,RIMS3,PMPCA,PREPL,HNRNPA1,DNAJC19,CASK,ZNF207,FAF2,SLU7,HSPB1,ZFAND6,GOSR1,TOMM40,ATP1B3,SNCB,TMSB10,FRMD8,TUBA1B,HTR2A,INPP5K,ATP6AP2,CDK1,MARCHF5,REP15,TRAPPC13,PSRC1,GDI2,CNIH4,MTCH2,WDR45,SNAP25,SYNDIG1,HSP90AA1,BTF3,SMG5,TNKS,NECAP2,ATP6V1A,MCOLN1,FTL,CAV1,CDR2L,STARD3NL,LCA5L,SUPT7L,PLEKHF2,CAV3,FKBP1B,BLOC1S3,AGAP2,TAX1BP1,RAB1A,SNX3,TRAM2,IFT57,SMAD2,ALKBH5,ZMPSTE24,TNPO3,CRB3,CD4,AP2A1,PTN,MTM1,EGR2,ARL6IP5,PSEN1,TNKS2,ATG9A,UBE2I,VAMP5,CACNB3,ARMCX3,RAF1,IL10,ROCK2,DDRGK1,TMEM50A,APPBP2,ADIPOQ,POLDIP3,CNTNAP1,VAMP7,RAB6B,RAB11A,TMEM106B,SNX14,HRH3,MSX1,RAB2A,MRGPRX2,EMC6,EPHA2,VPS28,STX1A,RAB6A,CORO1C,MAPRE2,ABHD17A,AGER,RHOB,PLEKHF1,S100A10,PREB,TRIM46,SH3GLB1,HSP90B1,NETO2,BORCS8,CIDEB,ATG3,PSMD10,PLEKHA8,TIMM23,VAMP2,TBC1D13,PEX3,RPF2,ATAD1,SPRN,LGI1,TRIM23,CTTN,STRADB,ASIC2,PLEKHJ1,FBXW11,SPCS1,TRAPPC10,TBC1D5,BRD3,NEFL,CFTR,LMAN1,WDR83OS,RAB9B,TBC1D17,EXOC5,EXOC8,BCS1L,SVBP,ERCC3,ARF1,MADCAM1,FKBP8,NOP9,TMEM30A,SRPRB,GNPTG,SKA2,BLOC1S2,RRAGA,VPS4A,ARHGAP21,CHMP1B,RRP7A,ADORA1,SCAMP5,TMEM87A,P2RY1,COMT,AZGP1,TRIM27,DDIT3,NETO1,TOMM70,CHCHD4,IKBKB,AGAP1,MKKS,AP1AR,TRAK2,CLN8,RAD21,CNTN2,PTGDS,SLC6A4,TPBG,SRP54,RAB32,OSBPL8,EZH2,MREG,CEP41,FBXO22,JUP,CETN3,STX12,PGR,GOLGA7B,RAP2A,TMED5,GABARAPL2,UFD1,TSPO,RABIF,F11R,GLE1,SPCS2,CCDC22,RAB39B,PAQR3,RPL23,YIF1A,YIPF4,DESI1,ANKRD50,LIPA,LIN7C,PPARG,ARCN1,CAMK2G,SNX5,PDCD10,MAGOH,AP1M1,RAB5C,IFT25,RALA,CTNNB1,VPS26C,KDELR2,SLC1A1,SLC1A2,NOP53,PHETA2,LMNA,FAM53B,PEX26,ASB3,UBXN6,SELENOS,GABARAP,UNC50,PDIA2,FTHL17,RNF128,VPS26A,VLDLR,STX7,LRP6,TSPAN15,DDX39A,MIS12,STXBP1,MCPH1,BCAP29,SLC4A8,DERL1,SSX2IP,RAB27A,TUBA1A,ABCE1,FAM91A1,DVL2,TOMM40L,RAMP3,TEX261,KPNA6,SPTSSA,TIMM8A,H2AC4,SEC61B,ENKD1,SNX12,CCHCR1,RIC3,ATG4C,NUP153,TM9SF1,ARRDC3,NUP50,TOR1AIP2,SKP1,DUOXA2,LRRC4,COPE,DPP10,MX2,MYO6,YWHAG,DYNC1I1,CAMLG,UBB,ERP29,SEC22C,HSPD1,LDLR,CPLX3,AP1S2,ROPN1B,AP1G2,TNPO2,VPS33A,SNAP91,FLOT1,MAP4,TRAPPC6B,MLH3,TIMM29,RRAGB,CHMP2A,TSPAN18,SIN3A,SRSF10,SYN3,IREB2,SLC32A1,SNAPIN,CD36,EXOC1,UBE2B,JAK1,TIA1,RHOBTB3,TSPAN17,GUK1,SEPTIN6,DNM2,EMP2,RTN4,SMURF1,ILDR1,SFT2D2,CACNG3,TRAPPC1,PHYHIP,KCNJ10,CD63,GPAA1,ATG4A,SARM1,ATG16L1,GIT2,SEC63,CLTRN,TFRC,NXT2,SELENOK,CYBRD1,ESAM,SRP14,TMEM108,RILPL2,EIF4A3,RAP1A,MACROH2A2,UBL4A,RINT1,CLU,TMIGD1,ZDHHC4,GRPEL1,FCHO2,SYBU,NECAP1,PML,SRPRA,HCLS1,DISC1,SLC11A2,IGSF11,UBXN2B,FGF13,SRI,TESK1,LAMP5,SSNA1,KCNJ8,TERT,TSPO2,VPS16,NLGN2,NDP,DNLZ,CD2AP,LAMTOR1,SLC25A20,RAB19,RAB35,PACRG,CUTA,SNX10,DYNLL1,STX5,SEC23A,TOM1,CHAMP1,TMCC1,RAB8B,ARL4A,DAG1,CDK20,SLC25A46,SH3BP4,CALY,PPID,C1QL3,ANGPT1,MGARP,SRGN,TM9SF4,SQSTM1,RAB40AL,LEP,PHB2,ZMAT3,GOLGA7,EMC9,NDC80,MAIP1,MECP2,FBXO7,SNX17,SYS1,TRAPPC4,KDELR1,SEC61A2,TOMM6,DNAJC5,TRIM3,LYSET,SNCG,ALYREF,EHBP1,SNX1,RGP1,SNX11,BLOC1S5,NBN,SCG3,TMED3,ACTR2,STARD4,AP3S2,BORCS5,TOMM7 |
| 7.601e-16 | -34.81 | response to oxygen-containing compound | biological process | GO:1901700 | 1546 | 596 | 18204 | 5365 |
USP8,GPBAR1,HTR1A,CAV1,ACHE,STAMBPL1,EFNA5,MSTN,RUVBL2,MEF2C,CMA1,CDKN2D,FKBP1B,BRCA1,TACR1,MIR342,SMAD2,MYD88,SLPI,GFI1,HTRA2,EGR2,PSEN1,MIR146A,TXNRD2,CCDC186,CLDN1,IDE,ATP1A3,FXN,AQP3,GLRA1,SOS2,EPHA4,MIR200A,DEFB124,AKAP12,KCNB1,RGS19,RORB,MIR106B,PRDX3,CRYAB,SOCS2,MIR142,DAPK1,IFNAR1,CREB1,IGF1R,SFRP1,LY6H,PTGER2,FBXO32,SOD3,CDK1,LILRB1,KLF9,HTR2A,BCL10,INPP5K,REN,IL12A,ATP5F1A,HNF1B,CCL3,CYP26A1,CDK5R1,SETD7,OPRM1,IRF3,HSP90AA1,CHRM5,CSF2,KDM1A,GAD2,CAV2,TLR7,EDEM1,CRYGD,EIF4EBP2,MIR200C,OR51E2,ATP2B4,CHRM1,RAP1B,TWIST2,CRHR1,REG1A,HDAC5,MRC1,PRKCB,SHC1,MAP1LC3A,IRF8,GNA14,CCS,FOSL2,LTA,SOX9,STAT2,CBL,CTNNA1,CCR5,CCL21,MIR20A,CPEB1,HNRNPA0,GPX4,RAB13,ATP1A2,CYP1A1,LITAF,BRINP3,HBB,BECN1,TGFB2,MAP2K3,IL1A,SLC6A3,POLB,DPEP1,PLSCR3,IL18BP,LIAS,KCNMB1,EIF2B3,PCNA,AANAT,TWNK,FGF10,SESN3,GJB2,PEX13,SPP1,GLRX2,FMO1,DKK1,PTPN22,NFKBIB,COL3A1,GCLC,RMI1,OSER1,ADRB2,HAND2,MTDH,MBD3,CXCL1,SULT1A3,DDIT4,STAT6,CCR7,FOLR2,TRIM44,CYP27B1,EGR1,MYRF,SLC6A4,EPO,NR4A2,CHRNA7,EZH2,CHRNB2,EIF2B2,NCSTN,MIRLET7G,EDEM3,ESR2,IRAK4,CHMP5,JUP,SESN2,CDKN1B,CDO1,NQO1,MLC1,GAB1,BTG2,KLHL22,TSPO,RPL23,CCNA2,PTGER4,RPL15,PPARG,CYP7A1,CXCL13,LIPA,SP1,UFL1,ST6GAL1,TP53,HADHA,IDO1,HTR5A,GNAI3,MDM2,CXCL8,TNFSF10,LPAR1,BRINP1,IL13,CNP,SOD2,MIR34A,GPR173,CLEC7A,CYGB,HPCA,HSPA8,PTPN1,LARGE1,BRINP2,GHR,UGT1A1,PRDX2,PCGF2,COMT,GABBR1,P2RY1,TSHR,TLR4,KLF4,ZBED3,MICB,HOMER1,TOMM70,CDKN1A,LRAT,SPHK2,CYC1,HSP90B1,GLRA2,INPPL1,FOLR1,VAMP2,CXCL10,CITED1,ADNP,RB1,OGG1,TYMS,CYP11B1,SLC22A12,GPX3,RAB31,GUCY1B1,TRA2B,CASP4,PTGER1,NLRP3,CASTOR2,MIR17,GJA1,CFTR,NEFL,MAPKAPK3,FBXO3,PSMD14,PDCD1LG2,EDEM2,FOXC2,SLC29A1,CLDN3,H2AZ1,ROCK2,IL10,PTGFR,SRSF2,RAF1,ADIPOQ,TNF,SHMT1,CYP11B2,ACTB,PPP1R1B,RPS3,LY96,TRIM6,ATP1A1,RDH12,DBH,MIR145,TRAF2,CX3CR1,HRH3,PTK7,CDK5,RGS2,KCNMA1,RAB11B,RDH11,CXCL12,CLDN4,TOP2B,HMGB1,RHOB,DUSP10,AGER,PYCARD,HRAS,CXCR4,FBP1,MIR98,WNT10B,TXNIP,EDNRA,AQP2,PAX6,ADCY3,SIN3A,SMYD3,ELK1,TUFM,LDOC1,CIB2,CD80,HP,CD36,GUCD1,UCN,JAK1,MTAP,MGST2,RGS10,GNRHR2,RWDD1,ILDR1,PCK2,TLR9,PLCB1,TNFRSF1B,CXCL3,HADH,MIR96,MIR21,CDC73,MSX2,IL12B,UBE3A,MIR185,YWHAG,MIR223,ACVR1C,GNRH1,CXCL9,SLC2A8,DNTT,FOXP1,GNAO1,MMP9,BGLAP,CD86,MIR107,GNAQ,IL6,AHCYL1,CSK,CHRM4,TP53INP1,MIR379,EIF4E,ERRFI1,DMAP1,LDLR,CA2,MPV17,FOXP3,CD274,JUN,AKT2,PPP2CB,SLC1A3,GPR37L1,PELI1,PPARA,UPRT,RXRG,PRNP,PCSK9,MIR187,LRP6,TIRAP,USP46,ACP5,STAT1,PHC1,STXBP1,JAK2,PPP5C,BCL2L1,DIO2,ACACA,TUBA1A,KRT8,PRKCE,ADCY2,CRY1,GSK3A,RAMP3,AKR1A1,GNAI2,PID1,CD14,GRIA1,MIR320A,RPL27,RPL13A,XBP1,MSN,NCOA5,CNR1,CRKL,SOD1,AR,TRIM24,MIR221,PLAA,IL2,TGFBR2,MIRLET7B,NSG1,CALR,PIK3R3,PDCD10,UCP2,IGF1,NFKBIA,ROMO1,EP300,OXTR,RETN,GPX1,MT3,CXCL11,GPT,AGTRAP,BAK1,TXN,MAP1B,VDR,NPR2,SLC1A2,GSTP1,HYAL2,CTSK,TNFAIP3,GH1,CTNNB1,SLC1A1,IL1B,ESD,TGFB3,TBC1D4,AIFM1,AKT1,SLC6A1,PPP3CA,WNT7A,KBTBD2,P2RY4,CEBPE,ELAVL4,MIR182,DRD3,ITGA2,FKRP,GRB10,SMAD4,PFKFB2,SELENOS,TLR6,ALPL,MECP2,FGF23,NFE2L2,TICAM1,AKR1C1,ABHD2,AKR1C2,SRSF4,TIMP1,SLC38A2,AMIGO1,MAN1A2,PIK3R2,PIK3R1,EIF2B5,SHOC2,FZD4,CAPN2,OPRK1,TAB2,ICAM1,PIK3CA,TIAM1,F7,GPR37,MIR143,MIR15A,GNPAT,CAMP,TACR3,GPIHBP1,PDCD4,ROCK1,HBA1,P2RY12,GNG2,DAG1,SRC,CALY,CSH1,EXT1,MGARP,PRDX1,KCNJ11,INSIG2,LEP,FASLG,MIR140,PDE4B,EPS8,REG1B,PIK3CG,BACE1,PHB2,FIBIN,WBP2,PDE2A,FOS,CCL2,NPPC,MAP2K6,RPL10A,NHERF1,GNA11,OPRL1,NFKB1,MIR16-1,CHRM3,KCNJ8,DRD1,EIF2S1,TICAM2,CYP1B1,RARRES2,TLR2,G6PD,TRAF6,CD2AP,CD38,THBD,CDK4,STAT5A,PPIF,NPTX1,TRIB1,XRCC5,P2RY11,CCL19,VPS54,GRM2,SMAD3,SLC2A1,SARM1,STC1,YES1,TFRC,BIRC2,SLC23A2,CLTRN,RLIG1,GLUL,RAP1A,PLSCR4,WNT2,HNRNPD,GPAM,CRHBP,TAF9,TMBIM6,CD40,WDR83,NLRP1,GNB1,TMIGD1,STAP1,SELENOT,STK11,FCGR2B,TESC,S100A8,HDAC6,NKX3-1,NFKBIL1 |
| 7.635e-16 | -34.81 | ATP5F1B (ATP synthase F1 subunit beta) | protein interactions | 506 | 541 | 238 | 19454 | 5460 |
TUBB,B4GALT3,ACTB,ACKR3,CYB5R3,YWHAZ,HSP90AA1,ILK,KDSR,MTG2,AUH,CUL3,PMPCA,TOMM40,HSCB,PXMP2,ATPAF2,EXD2,ATP5IF1,TACR1,ATP5F1E,PSMA3,HADHA,TERT,ATP5PO,ARMCX3,MYL6,NDUFA5,ANXA7,LNX2,PRDX3,CDKN1A,NDUFS8,DIRAS3,EGLN3,OPRL1,PHB1,GJA1,ATP6V1A,CETN3,KRT8,GATD3,FXYD6,RHOG,HAX1,MRPS26,MTRF1,PTPN5,TMEM208,HNRNPA1,ATG7,EMC8,ATP5F1D,TRIM37,GPAA1,HSPD1,HNRNPA2B1,HINT2,COX8A,EZH2,NGB,NDUFS6,RAF1,B3GNT2,FAF2,GFPT1,CYB5R1,NDN,UQCRQ,VIRMA,CCNF,SCAMP2,CHRM4,MSN,CDC73,NDUFB10,ATP5F1A,HMOX2,TUFM,PPP1CC,AR,CERS2,NPM3,PDHB,FBXW7,RPL4,RPA3,NCDN,VIPR1,SQSTM1,GRM2,METTL14,MTRES1,ATG16L1,UQCRC1,CDK7,ASB11,ATP5PD,CDK9,AIFM1,RCHY1,TES,CRBN,POR,P2RY1,RELL1,GRSF1,CALR,ATP5MG,EMC4,HDAC6,HUWE1,TRIM63,FBXO25,FASTKD5,SMN1,RIGI,RAB1A,FAF1,SFXN1,HAPSTR1,EMC2,SLC35F1,TNFAIP8L1,NDUFS3,FBP1,NDUFA2,TRIM6,MRPL11,AURKAIP1,EEF1A1,PSMD4,TAGLN2,SLC22A12,ESR2,TACO1,VDAC2,DLST,CCDC90B,MOG,RETREG3,ANAPC2,LAMTOR1,FBXW11,ATP5MC3,FIS1,MYC,PCCB,EMC1,NDUFS2,UFL1,STAU1,ADRB2,PHB2,RPP14,CERS6,HSPA8,HDAC5,AKAP1,PPT1,CAV2,PIH1D1,CSNK1A1,TOMM22,SLC19A2,TANK,YIPF5,UQCRH,HSP90AB1,COX14,CORO1C,AGR2,NDUFB8,IFI16,DIRAS2,YWHAG,CTNNB1,DDRGK1,KRAS,VDAC1,TMEM88,PDHA1,NDUFA12,CCR1,RPL18,SOX2,TUBA1A,ISG15,EEF2,MSX2,KCTD9,UQCRC2,PSMA6,SPOP,CHCHD4,RC3H2,ABCG2,UBE2H,EXOC5,HSPA5,BAP1,RAB9A,GFM1,P2RY12,GPR35,FGFR1,HEXIM1,UBE2M,CYC1,CFTR,CAND1,PLG,TMPO,MYL12A,SSBP1,SDHB,COX4I1,LHFPL4,TMEM70,RPS2,COX5A,RAB3B,SMIM11,MEPCE,MAP1B,ATP5PF,GLCE,DHX9,TFRC,TFCP2,GFM2,SLC25A24,RNF8,UBL4A,ATP5PB,MTCH2,CDK4,METTL15 |
| 8.031e-16 | -34.76 | SRP-dependent cotranslational protein targeting to membrane | REACTOME pathways | R-HSA-1799339 | 115 | 78 | 10285 | 3229 |
RPL35A,SRPRA,RPL24,SRP72,SPCS2,SSR2,RPL23A,RPL7A,RPL28,SSR1,RPS14,RPL6,RPSA,RPS20,RPS24,SEC61A1,SPCS3,RPS16,RPL3,FAU,RPL32,RPLP1,SEC11A,RPS4X,RPL13A,RPS29,SRP54,RPLP0,RPS13,TRAM1,RPL10L,RPL27A,RPS27A,RPLP2,RPL8,SEC61G,RPS5,RPN1,RPS26,RPL15,RPS17,RPS28,RPL22,SSR3,RPL17,RPS3,RPL26L1,RPL10,RPL35,SEC61B,SEC61A2,RPL19,RPL12,SPCS1,RPL9,RPL31,RPL18,RPS12,RPS2,RPL27,RPL4,RPS11,RPS23,RPL37A,RPL7,UBA52,RPS9,SRPRB,RPL23,RPS15,RPL29,RPL10A,RPS27L,RPL26,RPS7,SRP14,RPL39,RPS10 |
| 8.915e-16 | -34.65 | MCM2 (minichromosome maintenance complex component 2) | protein interactions | 4171 | 1055 | 413 | 19454 | 5460 |
WDR82,PSME2,FUBP3,GLRX,CCT7,HSP90AB1,RPS10,HNRNPL,SNRPA1,SNRPD3,XPO1,YWHAG,YWHAH,CTNNB1,ACTR3B,DDX1,MGMT,MAGOH,H2BC17,EWSR1,FAM168A,RPL31,FBXO3,ABCF1,RPS4X,TFG,HNRNPF,RUVBL1,TUBA1A,RPS7,EEF2,MOB3C,RPS23,TUBB4B,H2BC1,MCPH1,PSMB6,RPL10,ESR2,TAGLN2,MATR3,MYC,HNRNPC,LDHB,HNRNPAB,SFN,RPS26,H1-1,SERPINH1,CCT2,S100A11,CYP1A1,H2AZ2,SF3B1,DDX5,RPS28,GINS3,LYPLA2,PHB2,SERPINB6,EEF1G,PSMB3,FAM81A,DSTN,CDK6,MTAP,RPL32,MYL12A,CAND1,RPS27L,MIF,TPM3,GAPDH,KPNA1,H2AC4,RPL24,CLPB,DHX9,PSME1,RPL17,H3C1,HNRNPK,CSE1L,GNPNAT1,ATP5PB,RPSA,TP53,CBX3,CAPZA2,CALML5,CFL1,MTPN,PSMB2,TRIM32,SLC25A1,RPL7A,UBE2H,PGK1,DERL1,SNX33,RPL27,MAIP1,BAP1,PML,UGP2,CLU,AGO1,CDC42,HBB,RPLP2,BRD9,RPL9,PSMB5,SRSF10,PPIA,DHX15,HNRNPA1,SIAH2,PDIA3,HMGA1,INO80E,HNRNPD,COTL1,PCNA,BAG2,SLC25A5,HSPD1,HNRNPA2B1,RPS27A,RAD21,SSRP1,ASF1A,ACTN4,PPP2R1A,FAF2,ZNF263,DCAKD,RPS11,RPN1,CTNNA2,PRKAG1,GDI2,NME1,SNRPD2,RPS9,MAT2B,EIF4A2,PRDX2,SIAH1,TAB1,TUBB,RPS29,SLC22A17,PKP4,RPS5,SCFD1,HSP90AA1,PFDN2,YWHAZ,BRCA1,PYGB,AZGP1,YTHDF1,MYH1,ACTL6A,CFAP418,ARCN1,SLC25A3,FKBP1A,H2AC1,PSMB1,ALDH1A3,RPL12,ACTA2,TOMM70,RPL35A,THOC1,H2AC14,SPATS2L,NME2,CPNE2,RPL23A,VTA1,H2AC6,PTGES3,HUWE1,FN3KRP,FARSA,H2AJ,CCT5,GINS4,RPS12,MSN,CCNF,ENO1,CTNNA1,EIF2AK2,UBE2L3,UBB,VIRMA,PNP,MGST3,FBXO7,RPL26,AP2A1,SDF2L1,TCEA1,SPCS2,RPA3,SOD1,FBXW7,KDELR2,UQCRC1,SF3A1,SEC22B,UBA52,CARHSP1,RARS1,RPL26L1,CHMP1A,PICALM,MAGED2,S100A8,FABP5,LANCL1,FAM98A,TCP1,PPIB,YWHAB,HSPB1,FKBP4,SEC11A,PDIA6,RBM3,CCT8,PABPC1,RPL28,KRAS,H1-6,RPL18,CRKL,KDELR1,ATP5F1B,SPCS3,HDAC5,HSPA8,EP300,HIRA,XRCC5,UBE2D3,STAU1,NUP62,RPL27A,EEF1B2,SYNCRIP,GTF2B,IAH1,RPS16,CSNK2A1,KARS1,USP15,RPL10A,LANCL2,ABCE1,RPL3,NOSIP,TCEA2,SLC25A11,CAPZA1,H2BC14,IMP4,TMEM33,KPNA2,H2AX,CDK4,MTCH2,TAB2,ABHD14B,MOB4,RPS3,ACOX1,UBN1,BUB3,PYGM,RPL10L,H2BC9,RPS17,MAT2A,SUB1,SERPINB1,CALU,DNAJC10,HNRNPH2,ORC6,HSPA5,MARS1,H2AC13,GTF3C4,CFTR,XBP1,RGS7BP,CAPN1,ING5,GSTP1,UBE2M,HEXIM1,ACACA,TCP11L1,H2BC11,RPA2,OCIAD2,PHB1,RPL7,SNX1,EIF3D,CLPX,PSMD3,PRDX1,LYZ,AHSA1,RPL23,UBE2D1,CSTA,MCM6,G3BP1,GFPT1,E2F4,RNF126,EZH2,CDC7,RPL37A,CPSF1,RBBP4,DYNLL1,GGH,MCM3,MCM4,LMNB1,HADHA,SKP1,MCMBP,PRDX3,MYL6,ATP5PO,APOBEC3C,SEC23A,SRP14,H2AZ1,G6PD,TOP1,HDAC6,CALR,ORC5,DNAJC7,HSD17B10,EHD4,H2AC25,GLUL,RPS13,ARF4,CTNND1,CCL2,EEF1A1,RPL15,SERPINB9,TBK1,YTHDF2,PPP4C,ILF2,SRP72,MRPL49,RTRAF,GANAB,RPS20,PTEN,TRIM24,RPL22,MAGOHB,TXN,LDHA,SLC25A4,RPL13A,ATP5F1A,AR,KPNA6,TUFM,GMPS,CSK,IL2RB,SEC13,CHORDC1,IVNS1ABP,H2BC12,CSTB,MYH2,POLDIP2,NPM3,SMC4,ELP3,CNP,RPS14,MYL12B,EEF1E1,CCND1,CDAN1,RPLP0,MACROH2A2,JUP,LMNA,CDK1,TIMM23,HSP90B1,H2AC7 |
| 9.150e-16 | -34.63 | RC3H1 (ring finger and CCCH-type domains 1) | protein interactions | 149041 | 676 | 285 | 19454 | 5460 |
GARRE1,NKRF,RPL23A,HSD17B10,CNOT7,NOC4L,THRAP3,FARSA,RPS13,MRPL22,CNOT6L,SNRPG,IL6,RIGI,PRDX4,MRPL11,YTHDF2,CD2BP2,EEF1A1,UBE2V1,RPL15,UBE2B,ILF2,SRP72,H2AZ1,AIFM1,RPL12,KRR1,MRPL50,EIF2B2,TOP1,NCBP2,MRPL24,NOP9,MOV10,GRSF1,SPATS2L,MPHOSPH10,PNO1,SQSTM1,H2BC12,MTDH,EIF5B,RPL4,MRPL20,BRIX1,RPS14,PIP5K1A,SNRPN,EDF1,CNP,MRPS34,UBE2F,RPLP0,MRPL53,TUBA1B,SMAP2,PRKRA,RPS12,ALB,RPS20,RAB14,RPL13A,UBE2L3,RPL22,STK38L,PYCR2,ATP5F1A,NONO,PAIP2,AP2A1,SLC25A5,HSPD1,HNRNPA2B1,ZC3H7A,SRSF7,BAG2,RPS24,TNF,G3BP1,RBBP7,ZBTB14,MRPS17,SRSF4,RPS27A,UBE2A,RFC3,HSDL2,RPL29,RPN1,DTWD2,RPS11,SNRPE,SART3,RPL9,RPL8,MRTO4,RPLP2,RPLP1,NOP58,RPL7,CCAR2,PPIA,SRSF10,NUP35,DHX15,PRPF19,PRDX1,MRPS35,STOML2,HNRNPA1,ZCCHC9,MRPS26,HAX1,HNRNPD,RPL23,UPF3B,HADHA,CCDC86,RNF10,YTHDF1,CMAS,SKP1,G3BP2,WDR77,LARP4B,IRF2BPL,SLC25A3,FAU,RAN,SNRPD1,ARPP19,SNRPD2,RPL37A,MRPL23,TAB1,TUBB,RPL35,SPINDOC,RPF1,UBE2V2,ERH,SNRPB2,PRRC2A,RPL19,NOP16,PRPF31,RFC5,IRF1,ZNF668,RPS29,NOA1,DCAF4,RPS5,MRPL52,SLC25A11,RPL3,MRPS18B,DHX9,HNRNPK,IMP4,KPNA2,RPL17,SRFBP1,RPSA,TNRC6C,RBM34,PSMC3,SYNCRIP,SSBP1,MRPS9,ALYREF,UBE2N,RPL32,UBE2G2,RPS16,NKAP,RBM42,DKC1,CMSS1,TMA16,RPL24,SNRNP70,RPS2,CDK12,AKAP8L,USP15,RPL10A,DDX46,RPL27,HNRNPH2,RPS15,STK38,MRPL41,WDR55,HSPA5,SPTBN1,AGO1,ZNF326,LUC7L3,RPS3,PHAX,SRPK2,RPF2,SLC25A1,CEP85,RPL7A,RPS17,MRPS16,RC3H2,IGF2BP1,RPL31,PABPC1,RBM3,LSM14A,TRIM21,EWSR1,FAM168A,RTCB,PDIA6,HNRNPF,RPL28,RPS4X,HNRNPDL,TRMT1L,TUBA1A,RPS7,ZRANB2,RPL18,RPS23,SRSF1,FUBP3,CORO1C,FAM98A,HNRNPL,RPS10,LYAR,SNRPA1,SNRPD3,PEG10,DDX50,CNOT2,ICOS,WWP2,YWHAG,DKK1,CNOT8,PPIB,CPEB1,QPCTL,DDX1,YWHAB,HSPB1,SNRPA,PYM1,XRCC5,RPS28,SF3B1,HSPA8,FXR2,SRSF2,HNRNPA0,TRA2B,PHB2,STAU1,RPL27A,PABPC5,MRPL12,NUFIP2,EIF4B,PRMT5,MATR3,ATP5F1B,SNRNP40,RPL10,HNRNPC,HNRNPAB,CIRBP,CKB,H1-10,MRPS25,RBM27,RCL1,DNAJB6,POLR1B |
| 9.418e-16 | -34.60 | RPS11 (ribosomal protein S11) | protein interactions | 6205 | 458 | 208 | 19454 | 5460 |
MATR3,USP16,ESR2,RPL10,CMTR1,PRMT5,SMU1,PHF21A,ATG3,RPS26,COP1,MYC,SFN,BTF3,UFL1,EIF1B,STAU1,RPS28,HSPA8,HDAC5,ADSS2,EIF4B,PIH1D1,MTF1,RPL27A,PAFAH1B1,PRR13,RPS10,EED,AGR2,DRG1,MAGOH,WWP2,RPL6,RIOX2,CPEB1,XPO1,CTNNB1,DDRGK1,KRAS,RPS4X,RPL28,RPL31,RUVBL2,RAB4A,RPS23,RPL18,SOX2,NCSTN,RPS7,RPL10L,SMURF1,SF3B6,RPS3,PSPC1,SEC61A1,SRP54,EIF2S2,EIF3G,RC3H2,TRIM23,PDCD4,CDKN2AIP,UBE2H,PSMG3,RRP7A,RPL7A,RPS17,RPS15,HSPA5,RPL27,BAP1,NLE1,HSPB2,RNF113A,RPA2,WWP1,HEXIM1,UBE2M,KLF4,FBXL19,CFTR,RPS16,CAND1,RPS27L,TMPO,RBM42,CDC5L,RPL32,TUBG1,SNRNP70,RPL24,RPS2,USP15,RPL10A,ENY2,COPS5,CSNK2A1,MEPCE,RPL17,EIF1AD,SNIP1,RPL3,ABCE1,DHX9,DNAJC2,UBL4A,RPSA,EIF4A2,RPL35,PRRC2A,RPL19,ARF1,FAU,RPL37A,CDC7,SEC61B,RPS9,RHOB,BRCA1,RPS5,ACO2,CUL3,RAB11A,RIOK2,RPS29,G3BP2,LARP4B,WDR77,NOP58,RPL7,RPL8,RPL9,FOLR1,PHB1,RPLP1,RPLP2,MRPL18,AHSA1,RPL23,PDAP1,MAP3K14,EIF3D,G3BP1,TRIM37,RPS27A,EIF2D,RAD21,TRIP4,RPS24,EZH2,BZW2,CHMP4C,B3GNT2,OTUD6B,NDN,RPL13A,DUSP10,RPL22,CCNF,EIF4A3,METAP2,PRKRA,PTEN,RPS20,RPS12,ASCC1,PPIG,FBXO7,RPL26,PPP1CC,TUFM,AR,HMGB1,FBXW7,RPL4,PIAS1,RPA3,PNO1,METTL14,RPL26L1,RPLP0,RPS14,EIF3J,CDK7,RPL35A,TOP1,MDM2,CDK9,MRPL24,RPL12,RCHY1,KRR1,MOV10,HDAC6,VRK1,NOC4L,RPS13,SOCS2,VPS16,EIF3E,RIGI,RPL23A,SRP72,FBP1,EEF1A1,RPL15,PGM1 |
| 1.142e-15 | -34.41 | FBXW7 (F-box and WD repeat domain containing 7) | protein interactions | 55294 | 1181 | 454 | 19454 | 5460 |
TES,NHEJ1,EIF4E2,HRAS,RPL12,NCBP2,RPL35A,SPATS2L,ATP5MG,PMM2,MOV10,RPL23A,TGIF2,RIGI,VPS16,EGR1,PSEN1,RERG,HUWE1,SOX9,FBP1,POLR2G,ACTR2,GINS4,MSN,ALB,TUBA1B,EIF2AK2,ENO1,CINP,DEK,VIRMA,COPE,TMOD3,COL1A2,AP2A1,ASCC1,MIS12,ZKSCAN1,HELLS,FBXW7,MED30,TXNL4A,PCK2,SHOC2,RARS1,RPL26L1,FBP2,RPLP2,BRD9,MRTO4,RPL9,RPL8,STK3,SRSF10,HNRNPA1,MED4,HNRNPD,PDCD1,SRSF7,SKA1,PRPSAP1,BCKDK,HNRNPA2B1,SLC25A5,HSPD1,RAD21,SSRP1,GTF3C3,DHX16,NFE2L1,PPP2R1A,RPL29,JUN,FAF2,SART3,RPS11,RIMOC1,PRKAG1,EXOSC3,SEC61B,RPS9,SNRPD1,FAM91A1,MED17,IRF1,MRPL16,PYCR1,ILK,LSM14B,RPS5,HSP90AA1,YWHAZ,MED10,PSMA3,MED11,NOTCH2,ACTL6A,ARCN1,SLC25A3,EXT1,ALYREF,UBE2N,SSBP1,MRPS9,MYL12A,FZR1,CAND1,ELOC,RPAIN,TPM3,PPIL4,USP2,TAF9,SHC1,RPL24,MED29,MED27,GALNT12,DHX9,EFHC1,RPL17,HNRNPK,CSE1L,PSMA5,NUP107,NEDD8,KIF1C,CENPM,TP53,ATP5PB,BIRC5,AGER,DISC1,CDK8,DDX42,EXOC3,PTPMT1,CSNK2B,PSPC1,UQCRC2,DYRK1A,EGLN2,STAT5A,CFL1,RPL7A,PSMB2,AKT1,SLC25A1,DTL,MRPS16,CCDC65,PML,MAIP1,RPL27,STK38,RPS15,IGFBP3,LUC7L3,RAG1,DYRK2,HDHD5,SIN3A,SNRPD3,HNRNPL,ECHDC1,RPS10,CTNNB1,YWHAG,LRRTM1,XPO1,RPL6,IFI16,BAZ1B,MAGOH,DDX1,TRIM21,MYO1B,ABCF1,RPL31,RPS4X,RUVBL1,PSMA2,HNRNPF,RPS7,EEF2,RPS23,BTG1,SMU1,MTG1,PAPSS2,RPL10,EIF4E3,POLR2B,STAT1,MATR3,STAT2,UFD1,HNRNPC,PSMA4,SFN,MYC,SERPINH1,RPS26,CCT2,MED13L,SF3B1,SPECC1L,ITGAV,EEF1G,TRA2B,SRSF2,UFL1,ZC3H14,CSNK1A1,MED31,MAP2K1,SRP14,HACD3,AIFM1,CAV1,BARX2,ATP5PD,TOP1,EIF2B5,GTF2E1,NFKB1,MED21,PC,KLF10,KATNAL1,MSH6,EIF3E,MRPL22,RPS13,CTNND1,THRAP3,GGCT,SMAD1,RPL15,DDX39A,LBR,EEF1A1,MRPL11,YTHDF2,OSGIN2,CCDC47,TBK1,SRP72,ILF2,ACAT1,PTEN,RPS20,PRKRA,GANAB,RTRAF,EIF4A3,RPL22,RPL13A,LDHA,NONO,TUFM,PPP1CC,ATP5F1A,PYCR2,FXN,XPOT,TXNIP,SQSTM1,MTDH,TMEM126B,PRPF4,SPAG11B,RPL4,EIF5B,ELP3,CNP,EEF1E1,RPS14,MACROH2A2,CDR2,TMOD1,RPLP0,LSM2,HSP90B1,H2AC7,LMNA,JUP,CDK1,HP1BP3,PTGDS,RPLP1,TSG101,DNM2,THOC2,CGGBP1,RPL7,NOP58,EIF3D,DPY30,PSMD3,PRPF19,RSBN1L,KDM2A,DDX23,RHOG,RPS24,ZC3H7A,JAK1,NDUFA4,ANP32B,SRSF4,MCM6,AP1M1,KCTD17,G3BP1,TRIM26,RBBP7,WDR37,GTF2E2,MMAA,GFPT1,GFI1,FEN1,SF3B5,EZH2,CDC7,RPL37A,UBE2S,RAN,CPSF1,SNRPB2,RPL19,RPL35,RBBP4,MCM3,RFC5,TOMM40,SAMHD1,NOP16,VEZT,PFDN6,CCDC86,HADHA,FOXP2,SKP1,UNC45A,RPE,PRDX3,PPP1CB,IDH3B,H1-5,MYL6,MED23,ATP5PO,MCL1,EEF1B2,SYNCRIP,TMPO,DKC1,SHPRH,RPS16,TSEN34,TMA16,KARS1,RPL10A,RPS2,RFLNA,BECN1,SNRNP70,SLC35A1,TUBG1,THG1L,RPL3,SLC25A11,PALM2AKAP2,FKBP8,PPP3R2,H2AX,RPAP2,MTCH2,TFRC,EIF2S2,PSMC5,PSMA6,DCLRE1C,RPS3,SRPK2,RPL10L,GMDS,ANAPC15,RPS17,PTPN11,SUB1,MED22,SPRED1,RPF2,CALU,SNX5,ANAPC4,TWNK,CWF19L1,HNRNPH2,EXOSC4,MARS1,NAPG,KDM1A,XBP1,NEK2,SPTBN1,HECTD1,GIT2,CSNK1A1L,MAGED2,S100A8,POLR2L,SRSF1,HMG20A,LYAR,TCP1,EIF2S1,CIAO3,DRG1,YWHAB,FKBP4,RTCB,RUVBL2,TOP2B,RERE,MAGEC2,POLDIP3,RPL28,KRAS,TRAF2,RANBP1,MED9,MAX,RPL18,RND3,GTF2F2,GTF2F1,EFHD2,USP38,ATP5F1B,DNAJB6,H1-10,CHTOP,HSPA8,MRPS7,SSR3,HNRNPA0,RALYL,RPL27A,ADSS2 |
| 1.200e-15 | -34.36 | organic substance metabolic process | biological process | GO:0071704 | 7613 | 2485 | 18204 | 5365 |
PIWIL1,FAF1,CYP2C18,ZNF326,DROSHA,HEXB,FAR2,DET1,LGALS3,CDC123,WDR6,KPNA2,METAP2,CYP27B1,TRIM15,TRMT61A,RBM15B,UFL1,CHMP4C,RBM3,LYG2,PPP2R3A,TRA2A,TRIM52,ASB7,NAA35,B4GALT3,DDX46,CAMKV,SLC25A12,FYTTD1,NCBP2,DDX5,SLC25A39,RPL35,UBIAD1,MPG,AGA,HENMT1,MDM2,TRMT13,FADS2,PSMB5,PYGM,SUMO3,TP53,SPCS3,MAP1S,CLCA1,ST3GAL4,CRBN,RBMX2,FBXO30,ALKBH3,SORD,RARS1,MRPS11,USP39,ZNHIT3,RPL9,ZNF473,PTPN1,SCD5,INTS10,BAG2,PPIB,HSPA8,RPL6,CASP4,RNF152,ILK,TAFAZZIN,ZNF365,TNFAIP1,GGT7,CD2BP2,SLC22A12,FDFT1,SUPT5H,LSM3,TOP1,MED4,LRAT,MPST,LCN1,CASC3,ABCF1,NHEJ1,FUT8,GGCX,CHST7,CSNK2B,RNF133,RP2,PPM1D,PDHA1,H2AB1,NLRP3,BOLA3,KCTD9,TEX12,RDH12,MID1IP1,RPA2,ERLEC1,PHB1,CYP17A1,EXD2,GINS4,DUSP18,PPT1,MUL1,KDM2A,PITPNA,PCLAF,HECW1,RNF5,CCT8,GTF2A2,DUSP10,STUB1,DNAJC10,CYP4F12,CYP3A5,KLHL9,PLAC8,RSL24D1,RPL28,CERK,CDK5,SWAP70,RNF7,CMA1,SLC25A17,YAE1,LANCL2,NEU1,GSTA2,RUVBL2,USP5,GPBP1L1,TRMO,MOXD1,CHID1,CYP3A43,F9,RPL17,CSNK1G3,ATP5PO,FXN,FAM98A,PDP2,RPL37A,DGCR8,THAP1,MDC1,PSMB10,CDC37L1,NTMT1,PAAF1,GTF2H4,IL4,NDUFC2,MTMR6,PPP2R5E,ALDH1L1,FZR1,SECISBP2L,AGO1,CRYAB,SOCS2,SREK1IP1,RPS14,DDX42,TRIM68,TLR3,CDC16,HACD2,DYRK2,ABCB9,PDE7A,MAP3K12,UST,ACADSB,SLC48A1,SETD7,RNF34,GDE1,STK3,FBXO8,NDUFS8,MIF,NXT1,REN,SHPRH,EIF5A2,PCSK2,DRG1,HSPA14,SNRK,NUCKS1,VIPAS39,XXYLT1,FKBP1A,CTTNBP2NL,EIF4EBP2,CDC5L,OTULINL,PPTC7,CTSB,NR1I2,DHX15,ANAPC11,PRPF19,DNPH1,ING5,PELO,CWC15,IMP4,GLRX,LSM8,CYP1A1,QTRT2,MTRF1,DCAF5,DNAJC25,MVD,RBM23,PTPN5,DHRS7B,AZIN1,CPSF4,GHRL,CPEB1,CSNK2A1,HNRNPA0,BAG3,PPIG,ERO1A,PCMTD1,SOX9,CBL,NDFIP1,SART3,SLC2A3,PAOX,SUGP1,AANAT,LTO1,GZMK,SMNDC1,OTUD7B,LORICRIN,RPRD1B,LSM2,TMUB2,DPEP1,CHST9,GFM1,PLD3,FPGT,DUSP3,ZFAND2A,LRWD1,KLHL15,ST6GALNAC3,THOC3,SF3A1,ABHD13,RNF8,STAT6,MAT2A,FAM8A1,CFAP20,HAND2,PRDM4,MCM8,PRSS1,SRSF7,ZNHIT6,ADRB2,DDX4,RFC2,LDHA,DBR1,CHRAC1,FKBP2,RPP25L,OLA1,GLRX2,CLK1,ALKBH2,CTSA,VRK1,SAMHD1,PPM1K,GTF3C4,MGST3,METTL21A,UNC45A,NSMCE3,PDE1B,RPS11,MTPN,NUDT16,EIF3E,FGF23,CYP4V2,PPM1B,RRM1,ALPL,ELOVL4,HS2ST1,DEK,AREL1,CAPN2,NDUFB8,CAMK1,CDC40,PTDSS1,STT3A,CDCA3,KLF1,AGK,ST3GAL5,VKORC1L1,PIK3R2,TERB2,CTNNBL1,BSCL2,RNF148,PRKACB,YWHAZ,GFM2,ROCK1,THOC1,RHBDL3,GPIHBP1,SUPT4H1,CDSN,RPS10,ZFAND2B,CYP39A1,ELOVL3,NMRK1,FBXL3,TAF10,ATP5PB,PIK3CA,F7,MAP3K21,ZC4H2,DPH6,CHST13,APEX1,ACO2,BACE1,RPL35A,UTP25,FAHD1,RBM41,PDE4B,RNF41,UGT2A3,CD40LG,HSD17B8,PARP11,CHTOP,RB1CC1,LRP10,ADPRH,MMADHC,ASB11,SLC16A10,NPPC,RPL10A,GCFC2,DUSP6,PSMC5,CCL2,GLRX5,KIN,RBM42,EIF5B,DNAJC1,PDE2A,RMND5B,DPP4,RPL7L1,PIAS1,VPS54,TRMT10B,TBK1,CYP21A2,XRCC5,CDK4,ACOT13,DMPK,C1D,APOBEC3A,G6PD,RARRES2,MYLIP,MRPS25,USE1,TBCEL,PRPF31,TRIM32,TRMT112,UBE2L3,GPAM,MED9,ABHD16B,MED23,KBTBD6,PSMC4,CNOT6L,FA2H,DCUN1D5,UBAP1,APEH,VSIR,CERS2,RBM17,PRDX6,FBXW7,EAF2,S100A8,TESC,ZDHHC17,APOBEC3C,PPIC,TRIM5,SELENOT,ZC3H11A,SYK,NPY1R,NLRP1,MAK16,HNRNPL,PCYT1B,RPL7A,CHMP2B,OTUD6B,PNPLA8,BABAM1,SLC35C1,TP53INP2,NUS1,PRKAG1,TUFM,CASP12,URM1,GFPT1,RIGI,UQCRC2,PAX6,WNT10B,HM13,PREP,RIMKLB,AQP11,MDH1,DNAJB6,JKAMP,TNIK,UBE2S,B3GALNT1,PSMB2,MMP20,RAMAC,ATG7,HDAC3,UBA3,ZBTB16,MTAP,TKTL1,EIF4E,UTP6,AHCYL1,NDST1,CETN2,CDIPT,CHMP1A,PADI2,DDX39B,POLD4,IMMP2L,MAGEC2,THOC6,POP5,MCM6,UBE2K,ABHD4,MMP14,GNPNAT1,RPL12,RNF181,CLIP3,PAFAH1B2,GPD2,TENT4A,KLHL25,DUS4L,PPP1R12A,PPP2CB,ACTL6A,AKT3,FOXP3,RCL1,AGPAT5,SRFBP1,B3GALT2,ATP5MC1,PRKCE,PSMA3,GLCE,DCK,RGMA,SMU1,PARL,DIO2,CKB,PPP3R2,PIP5K1A,RPL4,TAF11,B4GALT1,USP46,PCSK9,HIRA,PAIP2,PAK2,CYTL1,TRIM63,IL2,GDPGP1,SOD1,MRPL52,AR,SNAPC5,RPL13A,RPL27,EHHADH,PNPO,XBP1,TERC,MND1,DOLK,PFDN4,SLCO1B3,SPSB1,BAK1,VDR,PRPS1,B4GAT1,CYB5R3,CLK4,FEM1C,PPP1R11,DIO3,FBXO9,PIP4P2,PSMA4,PSMD6,ASPA,SIRT7,DUSP26,ACO1,HACD4,RPS4X,FUBP3,RPL26,PDRG1,CCT7,GPC1,LBR,FKRP,CEBPE,BMP1,SIAH2,EDEM3,TPRA1,PYCR1,CEP41,SLC25A11,RPS5,FBXO22,ITK,AK3,ATP5F1E,AASDHPPT,OSBPL8,PCYOX1L,PLAAT5,MRPL47,CLN8,RAD21,POLR2L,LSM6,GNPDA2,UBE2H,GAPDH,PLPPR1,MYRF,CNOT7,CYP7A1,NSDHL,LIPA,ACOX1,CCNA2,CSNK1A1,NUDT7,TAMM41,RPL23,RNF20,GNPDA1,KDSR,TSPO,BTG2,PDE9A,STK24,DCP2,GLE1,RNF187,ACBD7,ZNF451,EEF1AKMT3,VPS72,PEDS1,IL21,APEX2,ZMAT5,VPS4A,FHIT,PFDN1,GNPTG,TAF7,IDO1,ORC6,HADHA,SPPL3,ENC1,CCL11,POLR1B,HUWE1,PTPN11,CDK6,NONO,TFPT,UGDH,FBXL7,SEC11A,CTRB2,DHRS3,TRIM27,FKBP10,TSEN54,MRPS18A,MTHFD2L,ATXN1L,FGFR1,VASH1,TTLL10,HELT,NDUFAB1,PTPRQ,PIWIL4,ACSS2,GGTA1,PLEKHJ1,H2AX,RAG1,FBXW11,SPCS1,ANKH,QRSL1,TRIM23,OGG1,RPF2,SPHK2,PPAN,ATG3,SLC29A1,BOLA2B,PSMD14,RPS28,UFM1,TRIR,ACOT8,FBXO3,CFTR,DIS3L,MTRES1,SCN2B,DDR1,KTI12,RPS16,AIPL1,STK38L,LDB1,FBXO31,TRAF2,ETF1,RPS3,EEF2,CINP,SENP8,TMEM106B,TRIM6,GALNT2,APPBP2,ADIPOQ,PLAAT3,ROCK2,CAB39,S100A10,RNF182,BRIX1,BATF,PRPF4,DPAGT1,MAPK10,RPS29,PSMD4,MME,KLK9,HMBS,RDH11,MTMR12,INO80C,EPHA2,MINDY3,PIR,STX1A,LDHB,FKBP1B,CMAS,ERLIN1,HSP90AB1,CBFB,CD28,PTPRZ1,OXCT1,KCTD17,MSRB1,LYPLAL1,CAV3,SMPD2,ACHE,ATP6V1A,TRIM11,PFDN6,DCTPP1,SMG5,MRPS33,FCF1,HTR1A,USP8,LDAH,CRAT,VCPKMT,SELENOO,RC3H2,SNRPA,POLR2I,YBEY,WBP11,PLPP6,TRIM26,ARL6IP5,PPP1R2,EGR2,ARB2A,RPS27L,IFIH1,NUDT5,ZMPSTE24,ZCRB1,TAF2,WWP1,ABHD12,COPS4,SELENOF,SNCB,IER3,ANAPC4,CREB1,HSPB2,SLU7,TDRD7,PRDX3,PTGES,G6PC3,SCNM1,APOBEC3G,FMO2,DNAJC19,SPON1,KLHL7,DNAJC30,NUDT18,MRPL16,THOC2,GLO1,PMPCA,WWP2,HNRNPA1,SOCS4,POLR3GL,NDUFA12,EIF2S2,USP15,HSP90AA1,CDK5R1,WDR45,CYP2F1,DAD1,REP15,HTR2A,INPP5K,OST4,MBLAC2,PELI3,MARCHF5,AHSA1,PAGR1,CTBP1,PRKCB,WDR3,SNRPA1,SNRPE,PFDN2,HPS6,NABP1,ERG28,EDEM1,USP14,MACROH2A1,HYCC2,ATP1B1,NDUFA2,CDK7,ETNK2,P4HA2,CISD1,MRPL36,GPX4,PRCP,TECR,MTARC2,BAZ1B,CWF19L1,ATP5F1B,SNAPC1,RING1,PCNA,TCEANC2,SHOC1,CPT1B,SRPK2,RBM7,PLSCR3,SLC6A3,KLHL12,SNRPD3,RNF39,POLB,TGFB2,DTWD1,FCN2,METAP1,PAK6,QPCTL,AP5S1,FARSA,PDHB,VPS4B,RTCB,RP9,PIWIL2,UBE2F,ADTRP,NDUFA1,TRIM37,USP13,PTPN22,NFKBIB,GAL3ST1,PDE8A,FMO1,ABHD14B,EIF3J,PXYLP1,PEX13,TTC4,NPM3,QNG1,BMPR2,ADGRG1,EDC3,MRPL50,BNIP3L,EXOSC3,CELF6,LYPLA1,AKR1C1,SNX17,UBL5,ETFB,B4GALT4,AKR7A2,MECP2,PGK1,TLCD3B,RPS24,IFI16,ASNSD1,TFIP11,NTRK2,GSTK1,CCT5,DDAH2,HS3ST3A1,FBXO44,NBN,METTL14,KRR1,DNAJC5,PQBP1,STYK1,SLC25A32,IRF1,SLC30A5,UTP15,C1GALT1C1,FAH,PIGK,MAN1A2,TMEM208,PGM1,PRKRA,OAZ3,MRPL53,MEF2A,DLST,USP30,DHX38,ZRANB2,TENT2,BIRC5,MACROD1,MEIOB,RPL8,DTL,NUDT4,GPR37,PGRMC1,FAU,RBM27,RNF121,AIG1,PSEN2,CHDH,PLCB2,METTL6,ISCA2,ATP5MC3,CHPF2,TRIM21,POLR2F,NOVA1,ATF4,MGAT4B,SF3B6,IDH2,HNRNPK,EXT1,GXYLT2,PTGES3,XPNPEP1,SRGN,MTMR2,NRDE2,MSRB3,CDK20,SRC,PPIL3,PPID,SUMO2,PSMB4,ANGPT1,RNASET2,ARG2,B3GNT2,NFKB1,KCNJ8,GLYATL3,THTPA,SUPT3H,PLP1,LIPT2,P3H1,MGAT4A,PRSS37,PHKA1,CLPX,FBXW4,IRF2BPL,FOS,PRSS12,CHI3L1,HNRNPF,SLC25A44,CYP2C9,RPAP2,MRPL18,HINT2,TXNL4A,URAD,ACAT1,TRIB1,SYCE3,TMEM59,RNF40,TTC1,GSTM4,THBD,NUDT12,CCNF,SELENOI,CHKB,NLGN2,TRAF6,NAE1,HNRNPD,TAF9,SNRPN,KMT5B,TEX19,EIF4A3,TRIM62,IRF2BP1,NXT2,SELENOK,CMTR1,SLC7A11,ATG16L1,TRMT1L,SMAD3,DUSP22,GPAA1,SNRNP27,AKR1B1,ATF3,NDUFA5,ELP3,DNAJC4,GFUS,TYW3,FNTB,PPAT,ZDHHC4,UBL4A,WDR83,SNAPIN,POLR3F,MPHOSPH10,RPL26L1,GANAB,RPLP0,RMI2,RMND1,H3C1,ELK1,CHMP2A,SNAPC3,LYAR,SIN3A,SLC25A42,EIF4E3,APTX,PHYH,ENPEP,DPH5,GPX5,PAFAH1B3,SLC35A2,METTL2A,INHA,ECRG4,MRPL22,RBFOX3,HADH,ABCC2,ESS2,RWDD1,MFN1,TIA1,USP2,COPS7A,CAMLG,UBB,ASMT,STOML2,DUOXA2,RNASE6,POLR3B,UBE2E2,RNF14,DPP10,SNRPB2,UBE3A,THUMPD1,WSB1,GNMT,LUC7L3,MRPL11,ADGB,IMPA2,SULT1B1,UPRT,OSGEPL1,SLC1A3,RNF122,OVGP1,PNP,MAT2B,MORC2,HSPD1,MRPS7,VDAC1,AKR1A1,PSMD7,KPNA6,ADCY2,EIF3G,PPP1R8,GSK3A,SPTSSA,BAD,DERL1,B4GALT7,CDKL2,CHPF,TSPAN15,CTDSP1,GAMT,CDK12,SKP1,PLAA,TRIM24,RIC3,MARCHF4,ATG4C,WDSUB1,GYS1,CRKL,SIAE,ADRB3,HTRA1,MMACHC,PSMB3,INMT,RPF1,CRTAP,NPR2,SLC1A2,BACH1,CTSK,RNF208,TMEM106A,GPX1,GEMIN8,RNF103,EP300,UQCC3,RFC3,CSTF3,PIK3R3,RPN1,WDR77,CRYL1,HSD17B10,NPC1L1,PRMT5,DDI1,MRPS34,UBXN6,DRD3,ISG20,SDHAF2,GRB10,SELENOS,DPH3,CDC7,GMNN,UBE2V2,RNASEH2C,AKAP17A,MRPS35,GON7,PSMB9,RPS26,GPHN,CYB5R1,GABARAPL1,B2M,EIF2B2,ATAT1,PRIM2,TCEA2,GTF2I,CBR3,RNF139,ZNF668,HMCES,HINT1,RBCK1,APOC2,GAPT,PTPN4,SIAH1,TRIM44,SLC16A1,MLF1,PAPSS2,RPL15,SGTA,APOBEC3H,SC5D,GMPPB,AOX1,F10,SNRNP40,NQO1,ALG2,PPWD1,BPNT2,KLHL22,CDO1,SUV39H1,PCMTD2,PPP2R1A,GSTA1,TNFAIP8L3,MRPL10,CHMP5,TNFAIP6,EPOP,NDUFV2,MAP3K3,FBXL14,PPP1R1A,LEPR,PTAR1,SOD2,NEK7,CSGALNACT1,MCM4,ANAPC16,OAZ1,ZC3H7A,CNP,ASCC1,FTSJ1,CDC26,PIGC,DDX23,ACCS,VCPIP1,STK4,CIAO1,GNAI3,ST6GAL1,MAEL,KLF4,SPTSSB,B3GALT1,INPP4A,PIP4P1,TOR1B,IP6K1,TMEM165,HMOX2,POLR1H,TSSK1B,MPP1,TLR4,RPS15,IMP3,CHORDC1,ITGAV,GEMIN7,CNOT8,MGMT,UGT1A1,EMG1,TMEM38B,TRIP4,CRABP2,SAP18,RAD1,LARGE1,GHR,PRPF18,RSRC1,TYMS,CYP11B1,CITED1,IK,ELOVL1,RB1,PTPMT1,RNF141,FOLR1,NFYA,CDK9,RBM5,DCTD,SDR16C5,ALDH1A3,SDHB,MFAP1,CTSD,MAPKAPK3,OTUD6A,PYGB,CHST2,GALNT12,GTF3C3,CNDP2,SNRPD1,CNTN1,RBM38,CEBPG,CDK8,DIO1,PDE12,PDIA3,RUVBL1,PSMA2,CYP11B2,HMGA1,TNF,GALC,SHMT1,GRPEL2,TMUB1,SF3B1,ATP5MK,EPHB6,MED11,HINFP,ABHD5,ITGB8,MRPL34,OAZ2,FITM1,FBP1,PLG,CSKMT,PSMD3,ORMDL3,TOP2B,SSU72,DDAH1,BCL6,RAB11B,SH3BGRL,PFDN5,NSFL1C,TOPBP1,BCKDK,RPS9,PLCXD3,MRPS16,MYORG,BLVRA,ANAPC15,STAMBPL1,GSTA4,FBXO25,FASTKD5,THG1L,EEF1E1,ALG5,GALE,SNRNP48,RPL18,FURIN,AK2,LSM10,EPHX1,MRPL57,IGFBP3,RPL10L,SLC6A8,CYP4F22,NUDT1,HTRA2,KLHL3,SPOP,SOCS5,HSPA5,MYD88,TRIM54,TAF5L,RCHY1,SAT1,IFT172,FBXO32,CSNK1E,ARMC7,RTRAF,IGF1R,PPIA,ABHD10,PLA2G4B,GGH,PGAP3,AUH,ZDHHC15,TUSC3,SPR,MMUT,EPHA4,GBE1,PELP1,ETFBKMT,IL6ST,GTF2F2,BARX2,NDUFB7,TSSC4,SRSF12,OSGEP,YWHAH,ATP5F1A,HERC3,PMM2,SLC6A7,STPG4,MAP2K1,PPP1CC,HGS,PRMT2,SLC19A3,CCS,CTU1,NHP2,TLR7,ZBED1,BUD23,RIMKLA,TSN,KDM1A,OS9,GAD2,TNNI3K,BECN1,TOPORS,ZCCHC7,GXYLT1,DICER1,PSMB1,POLA2,DNAJB9,BANF1,UBXN10,SF3B5,CNOT6,CHST11,DLG1,IL1R2,NSA2,HCST,RGN,SUB1,RPL7,TMT1A,EXOSC4,PDF,OLR1,MRPS17,ALG11,ZMAT2,TRMT5,LTB,RNF11,LIAS,HYCC1,RPL29,EIF2B3,PGAP2,TRIM8,PDE1A,RPIA,TPSG1,UCHL3,GTF2B,NEDD8,DHRS7,RLIM,OSBP,ATP5MG,GALNT4,GINS3,CCR6,UAP1,ISG15,RNF167,SULT1A3,ZNF345,MARCHF9,PGM2L1,MSL2,RMI1,GDPD3,COL3A1,AMACR,HSD11B1,SEPHS1,RPA3,SDF2L1,DHX9,FEM1B,SPP1,PLA2G15,FAM20C,RPL31,HMGCS1,RNF115,CCAR1,CMPK1,PRRT1,GTF2E1,ABHD2,RPS12,HSPB6,IL15,NDUFB4,MRPL41,PPM1G,GTPBP2,FABP5,BCL9,RCE1,TCP1,SLC52A3,ASB8,NIBAN2,PIGY,AK5,MRPL49,CRYM,TRUB1,CCDC47,ZNRF1,TRIM10,RAN,PIK3R1,SETD4,CUL3,SSRP1,CDK17,NDUFS6,PSMD1,PGA4,CPSF2,CACUL1,OARD1,LYPLA2,DECR2,ADRM1,CAMP,SERINC1,WDR55,DBT,GNPAT,MAGOHB,PAFAH1B1,WDR12,SPOPL,CDC23,GMPS,NDUFS2,ADK,NUP107,FIG4,RBMS2,COX11,RETSAT,ABCG2,GIN1,ANKIB1,TRMT11,ADH1B,VAC14,HNRNPA2B1,PIK3CG,INSIG2,CHST1,GTF2H2,NDUFB10,NT5C3A,TOR2A,G2E3,WRAP53,TRIM35,EXTL2,DCUN1D3,ATP5F1D,RDH10,CACNB4,CHRM3,PIGA,PIH1D1,DRD1,HSD17B3,MRTO4,H2AC25,DHRS11,MGAT5B,UCK1,EHD3,MAPKAPK5,POLR2B,WBP2,HPGDS,YIPF5,PTHLH,PICK1,AKAP8L,RNF10,CSNK1A1L,BPGM,RNF26,MECR,TRMT6,STAT5A,PPIF,PPM1M,MRPS9,SGMS2,MRPL12,GTDC1,MRPL13,DUSP9,CCNH,ENTPD4,TLR2,RPS13,ST8SIA5,DPEP3,CYP1B1,FKBP4,RLIG1,GLUL,MRPS18C,NPC2,PRKAB1,ASB1,YES1,BIRC2,SLC23A2,DUSP1,LACRT,MRM2,EGLN3,STAR,ERH,MCAT,SLC2A1,LHB,XPO1,UCKL1,KCTD10,TCEA1,WEE2,PRSS8,PARP2,POLDIP2,FOXA3,NME2,INTS12,NOL7,DPM2,SGF29,MRPL17,HDAC6,TMCC2,STK11,ALKBH4,LAP3,MED22,CCAR2,PSMC1,CH25H,PPME1,GK2,BFAR,SCG5,MSMO1,MED10,ACVR1B,DERL2,NOC4L,ARFGEF1,ASRGL1,DUSP21,NUDT19,VPS18,ACP6,PIGW,EXOSC1,TAPBP,MED27,NCAPG2,GTF2A1,MAD2L2,GMDS,ADSS2,PSMB6,PAPOLA,REXO2,DHRS4L1,MGME1,RPL27A,EDNRA,NMI,DHX16,OCRL,LPCAT3,DNAJB2,RBM34,SRD5A3,CDC73,DTD1,ST3GAL2,DNAJC3,B3GALT4,PLCB1,ORMDL1,ADM2,MGST2,SMG8,PSMB11,PPP2R5A,METTL18,RPL10,ENPP4,USP38,GP9,BAX,HEXA,TRAF3IP2,IL6,LAMP2,AGPAT1,TOM1L1,MMP9,ACAA2,LSM5,PAIP1,SEPHS2,PSMB7,ADAT1,ADIPOR2,DEGS1,NOP58,SLC2A8,RAB23,DNTT,CYP27A1,CHAC2,NKX3-2,ACVR1C,DCAF4,ACSL4,FBP2,POLR2C,SUCLG2,ZDHHC14,ERLIN2,DDX1,OXSR1,SF3B4,SLX1A,SMN1,DAPK3,PSMA6,HS3ST5,AKT2,GGPS1,HECTD3,RPLP2,COPS2,UHMK1,SLC37A4,DLAT,ERRFI1,DHPS,FUT1,CDK5RAP3,SLC25A10,SPRR1B,SYVN1,EGLN2,FN3KRP,ACER3,SCPEP1,PAXX,DOHH,RPRD1A,E4F1,PPP5C,TSG101,SLC25A26,NR1H2,MATCAP1,FTSJ3,PLA2G5,TP53I3,MSH6,TGFBR2,UBE2D1,RPE,HNRNPAB,TSPAN5,COQ8A,CPE,EIF4A2,TOLLIP,SLCO2B1,KIT,TNFAIP3,RBBP4,NUDCD3,GID8,GSTP1,INPP5E,ATP5PD,IGF1,APH1A,DKC1,UBE2W,ENY2,WTAP,CNOT2,UCP2,MRPL23,SGMS1,PSMA5,CHCHD1,TTR,GRSF1,NSG1,CALR,SKIC8,METTL15,MTERF2,RTF2,EXOSC8,UBA52,PCCB,DNAJC24,ADAM21,EIF4B,SLAMF9,PFKFB2,KBTBD2,ELAVL4,PPP3CA,CLP1,HERC4,AKT1,DYRK1B,IL1B,ESD,YTHDF2,RPS20,EIF4H,NCSTN,EZH2,UPF3B,NR4A2,CUL2,MNAT1,PTGDS,EPO,CHCHD4,PNPLA4,EGR1,IKBKB,FANCG,MKKS,ST8SIA4,DESI1,PPARG,POLE4,JOSD1,B4GALT6,UBR7,HECTD1,UFD1,COP1,SDHC,GSTO2,SPCS2,HDHD5,SLA2,PRKCQ,ADH1A,SESN2,FAXDC2,GOLGA7B,CYGB,COX10,PGAP4,UBE2D3,CHST10,HSD17B11,ABCC5,LCMT1,SVBP,ERCC3,CTSC,FKBP8,NOP9,SMG9,DCLRE1C,DNAJC2,POLE3,ENO2,EYA3,DDIT3,CMTR2,PLPP4,SRSF1,TBCE,COMT,PSENEN,CHMP1B,RRP7A,ADORA1,NFE2L1,GUCY1B1,TRA2B,NUDT3,ECHDC1,TFB1M,CGAS,STRADB,INPPL1,GSTT2B,DCUN1D1,PGGT1B,FRA10AC1,TSEN34,UBE2E3,EEF1B2,SH3GLB1,HSP90B1,ELOVL6,RFC4,USP16,RABGGTB,APOBEC3B,PIP4K2C,POMT2,PPIH,F2,EDEM2,AMT,PLSCR1,HSD17B1,CAPN1,PRKCA,LMAN1,WDR83OS,RNF144B,MTHFS,MCMBP,GANC,AZIN2,EIF4E2,ACVR1,RAD23B,TRAF1,RFC5,MSX1,DBH,PRKX,PPP1R1B,MAP3K11,DDRGK1,POLDIP3,NAA15,ZC3H15,MMP21,RBBP7,GID4,SRSF2,RAF1,SRSF8,STN1,BCCIP,HNRNPH3,GTPBP1,PYCARD,CARS1,CD226,HMGB1,KCTD11,FEM1A,DFFA,PITPNB,ZDHHC8,ABHD17A,MBL2,VPS28,KLK6,RAB6A,H2BC1,CDKN2D,ODC1,PIM2,NAA60,NME4,IDH3B,ST3GAL1,RPP14,ACOT6,POLR3H,CELA3B,PPP1CB,COQ8B,MEPCE,PRDX4,SOCS3,RBBP8,CAV1,NDST3,RBFOX2,TNKS,TAB1,MTG1,APOBEC3F,MRPS23,SNRPG,UBE2I,SNRNP70,IDE,RNF113A,DTYMK,SLC19A2,MTM1,PSEN1,TNKS2,MRPS21,RBM22,CYP2D6,MPHOSPH6,IRF9,SMAD2,BRCA1,ALKBH5,BUD31,TYW5,RPL23A,FBXO11,ZER1,ACTMAP,FAF2,DAPK1,ZSWIM7,CDC20,SLC35A1,HSPB1,SLC25A1,TDP1,MARS1,TPH2,FAAP100,GSTM3,CASK,MRPS28,CYP4F8,FITM2,MRPS26,PREPL,MED21,NFIL3,NAA50,GLYAT,CTDSP2,UBE2A,PWP2,CYP26A1,APOBEC3D,ISYNA1,DDT,SRM,OAT,POLR2D,SSBP1,ATP6AP2,CDK1,SNIP1,RPS6KA4,FOSL2,ORC5,EEF2KMT,COPS5,SUMO1,HNRNPC,RNF126,METTL25B,OAS1,SETD3,IDH1,CCT2,PGPEP1,SMAD1,LDHAL6B,COIL,KGD4,ILVBL,XPO5,CSTA,TST,ATP1A2,PYM1,PTTG1,HSPE1,ADAMTS20,TRIM22,MTF1,PLA2G12A,FEN1,MRPL9,AIP,ATP5PF,TWNK,FBXL4,ADAMTS1,CPT2,NUDT2,DRG2,RPP21,IL2RG,ACADS,KRAS,DCAF11,SAT2,DPY30,STBD1,PPP1R3C,MRPL40,GTF2H5,ADAMTS10,RBP2,MARCHF3,KLK3,MPDU1,RPL22,PROX1,CREBBP,ZDHHC24,GCLC,SLC5A6,PRSS23,PGAM1,GSTM2,EIF2D,DYRK1A,DRAP1,TMEM199,SLC38A1,PDIA6,UBASH3B,SPSB3,SMUG1,SRSF4,RTL4,AMY2B,AKR1C2,PTS,PRMT6,HNMT,GCNT3,FBXO7,NFE2L2,DNAJB4,BMPR1A,SACM1L,GOLGA7,HACD1,IVNS1ABP,NOB1,SMARCB1,SNAPC2,CCDC3,EIF1AD,MGAT1,EIF3K,PGS1,RPP25,EIF2B5,ALYREF,GTF2IRD1,DTWD2,TRIM3,PHKB,GSTO1,STK16,TRIM45,TESK2,ELOF1,CPSF1,SENP5,METTL22,RNF146,SERINC3,GALNT1,MED17,PLCL1,CBLL1,TCOF1,MRPL51,SNRPB,MCM3,POLR2G,SQSTM1,LEP,RAB40AL,CSTF2T,KCNJ11,MMP28,PDSS2,SLC25A21,NME1,SDR42E1,DAG1,EIF1B,SMARCA5,PIWIL3,SERPINH1,NDUFB5,FUT9,EIF2S1,RPL24,HS3ST1,SPATA2,TERT,GTF2E2,PABPC1,MRPL33,UBXN2B,MRPL20,ALOX5AP,BMPR1B,TFCP2,GSTT1,DISC1,SLC11A2,RPL32,UGP2,CBR4,PML,SNRPD2,NUDT9,UTP23,GRM2,MMAA,UMPS,NEK2,FMO3,CD38,CD2AP,DNAJC7,FAM20B,TPST1,ZDHHC16,MRPL24,TSR3,CSGALNACT2,NAA11,UBLCP1,GADD45A,NDP,FKTN,DNLZ,POLD2,PNRC1,TEX264,ELOC,PCBD1,NT5C2,ATG4A,SARM1,CRTC2,EIF1AX,PKNOX1,RPS7,RNASEH1,HSD17B6,GRPEL1,STK38,ADIPOR1,PSMA1,CLU,RPL19,CISH,OTULIN,ANAPC13,SDS,MED30,RPL3,BAP1,PMAIP1,CD36,LIG3,SRSF10,HYPK,IREB2,NDUFS3,RPLP1,DXO,HSPA13,PC,ADCY3,KHDC4,MED29,IFI27,RPS23,DCAKD,MLH3,ENTPD3,NEURL2,ELOVL7,PHKG1,DHRS4,KLHL24,CPNE1,ELP6,WDR82,ANAPC2,ETFA,ECD,RPS2,EEF1G,PCK2,SMURF1,MAEA,PRPSAP1,NGDN,SYNCRIP,OGDHL,HACD3,JAK1,UBE2B,GUK1,RHOBTB3,CREBL2,ERP29,NDUFB6,STAMBP,NANP,KBTBD13,PI3,GTF2F1,ABHD6,CSK,VIRMA,CRMP1,THRAP3,NIM1K,BRAP,RNASEL,FGR,IDH3A,RPS17,LANCL1,GAL3ST4,PPP4C,EEF1A1,NEUROD2,PELI1,ST13,PPARA,TRAF7,UCK2,RPL39,PAK5,TRIM34,TOP3B,HAS3,AURKAIP1,LDLR,ENO1,TRPC1,DMAP1,POLR1D,ASF1A,GSTM5,CRY1,UGCG,SMCHD1,ABCE1,ACACA,TUBA1A,DDX39A,MORF4L1,MED31,FBXL19,JAK2,PTEN,APOC4,DTD2,USP3,CAND1,TSR2,VLDLR,GALNT17,INTS6L,NUP153,UBE2M,ATP5IF1,PSMC3,STK26,UBE2N,RRN3,DESI2,CYP2C8,HPF1,RIOK2,EIF2AK2,POLL,SEC61B,MRPS18B,CYP2R1,CTNNB1,SLC1A1,IAH1,SHLD1,HYAL2,COPS7B,KLK5,TSNAX,GPT,NTAQ1,CYFIP2,RPSA,SNX5,DR1,CERS6,MAGOH,TTL,EIF3D,NAA16,PSMD12,PRKD3,COQ10B,ARMC8,POP7,GK5,KARS1,MAPK4,PDIA2,LSM4,DNASE1L1,RNF128,RPS27A,ASB3,INO80E,SMAD4,UBE2V1,UBE2G2,BRS3,DCAF16,PYCR2,NOP53,PHETA2 |
| 1.201e-15 | -34.36 | SNAP29 (synaptosome associated protein 29) | protein interactions | 9342 | 238 | 125 | 19454 | 5460 |
BLOC1S5,LAMTOR1,RHOB,NTRK3,SCFD1,COP1,FMC1,SYCE3,COX6B1,RAB11A,RNF40,STX16,RMDN3,SEC61B,NDE1,BET1,EHD1,SEC62,VAMP1,BORCS6,GOSR1,PHB2,PXMP2,STX7,EXD2,RAB5A,AKAP1,DCTN3,ARL14EP,RHOG,TRAF6,STX1A,MED4,LAMP2,ATG9A,RAB5C,XPO1,PPFIBP1,EXOC1,HNRNPL,RHOH,VAMP7,COX14,RAB35,STX5,FAAP100,VAMP2,STIM1,RAB4A,STX12,TRIM26,KRAS,EPHA4,VAMP8,NDUFA4,TMT1A,EWSR1,SKA1,STXBP6,AP2A1,NAPA,CCHCR1,UBE2H,RAB2A,VAMP5,ATF4,NTAQ1,DNAJC5,THAP8,RHOJ,CCNF,VAMP3,LURAP1,MOB4,PTPMT1,STX10,RPA2,PTP4A2,SSR1,FGFR1,STX17,SEC22B,CDC42,EHD3,CDK7,SGF29,YKT6,NAPG,TOMM20,RPA3,RHOU,ELOF1,TRNP1,DERL1,RAB9A,ESYT1,SLC25A46,LAMP3,VTI1B,ARF6,TXNRD3,LMAN1,STX6,CAV1,PTPN1,AIFM1,CDR2L,ARL10,HSD17B11,RAC2,SNAP29,KBTBD4,MTCH2,APOO,TRIM62,RAB3B,RNF20,STX11,FKBP8,TFPT,STX8,SFXN1,STX18,SNAP23,IGF1R |
| 1.276e-15 | -34.29 | regulation of signal transduction | biological process | GO:0009966 | 3114 | 1104 | 18204 | 5365 |
IRF1,BRMS1,TRIM3,AFAP1L2,MIR100,SHOC2,BPIFB1,CTNNBIP1,MIR296,NTRK3,CCDC3,LMO3,NTRK2,BMPR1A,SMARCB1,IVNS1ABP,NDC80,AKR1C2,PRMT6,TICAM1,NFE2L2,FBXO7,MIR29A,LPXN,UBASH3B,ADGRG1,BMPR2,SEMA7A,ADRA1A,SH3BP4,SRC,CDK20,MIR34C,DAG1,ANGPT1,FAIM,TNFSF12,EXT1,MTMR2,ATF4,WIF1,EPS8,TRIM21,HNRNPK,LEP,SQSTM1,PHB2,HEXIM1,SERINC3,IFNG,TAB2,DOK5,BIRC5,ARHGAP5,MIR34B,GPR37,RNF146,LGR4,PDCL,PRKRA,NLGN2,GADD45A,TRAF6,FKTN,TICAM2,NDP,MIR222,MIR181D,CD2AP,LAMTOR1,GSKIP,TRIB1,JPT2,NINJ1,GRM2,CCL19,SOSTDC1,PML,TASL,BMPR1B,CHI3L1,DISC1,HCLS1,TAFA1,IGSF11,KCTD16,CHN2,CRADD,TERT,SPATA2,NFKB1,WDR83,CISH,RALB,MINAR1,OTULIN,CLU,MIR205,STK38,ADIPOR1,STAP1,ATF3,NFKBIL1,NKX3-1,RPS7,FCGR2B,SMAD3,MIR24-1,CD63,DUSP22,ALKAL1,SARM1,LMBR1L,GIT2,TRIM62,DDIT4L,SELENOK,TFRC,CRHBP,TAF9,CCN3,EIF4A3,RAP1A,PIK3AP1,TMEM108,PEBP1,ELAPOR2,HACD3,GLIPR2,UBE2B,SMURF1,RTN4,RGS10,EMP2,CACNG3,MIR30B,MIR21,FGFBP1,VWF,MIR519D,CPNE1,LILRA2,MIR375,MSX2,TTC23,RRAGB,VAV2,SIN3A,TCF21,NDUFS3,ZNF592,PMAIP1,MIR210,TPT1,CD36,ENO1,MIR885,TRIM34,PRL,OTX2,MIR186,FLOT1,PPARA,PELI1,GPC4,GPR37L1,PAK5,VEGFC,TRAF7,MIR10A,GRM1,TMEM196,ADRB1,NEUROD2,MIR449A,FGR,BRAP,MIR185,IL12B,UBE3A,RNF14,FOXP1,PEA15,YWHAG,MIR107,UBB,DLGAP4,USP2,STAMBP,ERP29,ABHD6,RSAD2,CSK,MIR206,EIF2AK2,CD14,GNAI2,AATF,ADRB3,HTRA1,RRN3,MIR497,TRIM24,CARTPT,DIRAS2,UBE2N,CRKL,NCOA5,ARRDC3,MIR221,IRAK1BP1,STAT1,TTI2,MIR573,BST2,TIRAP,TSPAN15,BCL2L1,PTEN,JAK2,LIMS2,P2RY10,FGD2,UGCG,BAD,DEFB114,G0S2,SSX2IP,RAMP3,DVL2,GSK3A,CRY1,NOP53,MIOS,STARD13,MIR1271,ZMYND11,UBE2V1,LMNA,FAM53B,SELENOS,SMAD4,GRB10,TANK,ARHGAP15,SDHAF2,DRD3,MIR99A,GABARAP,PRMT5,MIR92B,BOK,EP300,SNX5,PDCD10,VDAC2,TMEM106A,KLK5,RALA,GPX1,CYFIP2,CTNNB1,CTSK,HYAL2,MIR106A,SESN2,PRKCQ,RELL2,JUP,GPNMB,SLA2,TMEM237,ZNHIT1,UFD1,RAP2A,F11R,CCDC22,CSNK1A1,SRARP,RPL23,SFRP4,PAQR3,RACGAP1,LIPA,PPARG,IL34,IKBKB,TGFB1I1,EGR1,GAPDH,CNOT7,NR4A2,FSTL1,TPBG,EPO,IL7,EZH2,OSBPL8,CHRNA7,RPS20,FZD6,YTHDF2,LEMD3,MIRLET7G,PYCR1,ADORA1,FGF22,NKIRAS1,P2RY1,FGFR1,MIR340,PRDX2,GHITM,NONO,DDIT3,FAM13B,EYA3,DHRS3,NETO1,PTPN11,LCMT1,SPPL3,FKBP8,CTSC,MIR133B,CCNY,RGS1,DIPK2A,RRAGA,LPAR1,CXCL8,MIR34A,ARHGAP21,UBE2D3,ITGA6,ZNF451,AZI2,CLEC7A,EIF4E2,AIPL1,ACVR1,PRKCA,DDR1,UFM1,PLSCR1,CAPN1,RHOH,PIP4K2C,CCR2,F2,MIRLET7C,GAS2,HAPSTR1,SPHK2,ZNF622,RELL1,INPPL1,PSMD10,RPF2,MIR424,CGAS,STRADB,CTTN,ADNP,NKIRAS2,FBXW11,KLK6,EPHA2,RGS2,MPIG6B,PTK7,CDC42SE2,STX1A,MAPRE2,HMGB1,ABHD17A,CXXC5,MIR23A,HRAS,PYCARD,MIR361,AGER,PLEKHF1,CD226,TMEM198,CXCR4,SLC39A10,RAF1,IL10,ROCK2,MAP3K11,DDRGK1,RBBP7,LBH,FGF17,CRLF3,ADIPOQ,LY96,TRIM6,RPS3,TRAF1,CX3CR1,TRAF2,MIR145,DBH,MSX1,SMAD2,MIR342,SNX3,BUD31,BRCA1,MIR208A,ARHGAP19,GFI1,CNKSR3,ZMPSTE24,TRIM26,HBEGF,CD4,RNF113A,LILRB4,PSEN1,TNKS2,ARL6IP5,PPP1R2,MTM1,FAM83B,GPBAR1,TAB1,TNKS,RC3H2,USP8,SLC20A1,TRIM11,IFNB1,CAV1,SOCS3,MEF2C,MSTN,CAV3,LYPLAL1,CDKN2D,PIM2,VGLL4,CD28,TAX1BP1,HSP90AB1,INPP5K,HTR2A,DDT,SNIP1,PELI3,APLN,ATP6AP2,CYP26A1,AKIP1,SOCS4,SMAD5,USP15,SOS2,DOK6,LRRC14,WWP2,DLX1,PEG10,G3BP1,GPR17,IFNAR1,DAPK1,MIR142,ZFAND6,HSPB1,MIR490,MYC,MIR126,FRMD8,IER3,CTNNA1,AIP,ARHGAP25,TRIM22,PRCP,MIR20A,CCL21,PICALM,LITAF,ADAMTS20,SLC35F6,IFI35,ACTN4,MIR1260B,MIR708,CAV2,TMEM170B,RIT2,TMOD2,ATP2B4,MIR200C,MAD2L1,H2BC11,NLRP6,IRF7,COPS5,RAP1B,OAS1,RNF126,PAGR1,CHGA,SHC1,PRKCB,DYRK1A,GCLC,PDE8A,NFKBIB,PTPN22,SOX2,CREBBP,CYTH4,PROX1,ENHO,MTDH,GREM1,MIR152,CDH13,DDIT4,CRYBA1,IL1A,TGFB2,CHP1,PAK6,PAK1IP1,MBD5,KRAS,NOTCH2,ACTA2,SPRED2,NCK1,GKAP1,FGF10,YWHAZ,OSM,MIR30E,PRKACB,PIK3R1,ZNRF1,PIK3R2,NR0B1,CUL3,CCNB1,RXFP2,OPRK1,MIR218-1,FZD4,NIBAN2,FGF23,PRELID1,BCL9,CARD19,FABP5,PPM1B,RPS12,TLR1,NF2,LAMTOR2,SAMHD1,TIMP1,RNF115,PRRT1,MIR874,RALGAPA2,IL23A,VEGFA,RGS6,GTF2H2,PRDX1,LAMTOR3,PBLD,CSH1,IL18,RB1CC1,PIK3CG,THY1,NECTIN2,PDE4B,MIR140,FASLG,TNFAIP8L1,INSIG2,RNF41,SCHIP1,ICAM1,TCIM,NLGN1,RGS7BP,NLE1,PAFAH1B1,F7,TIAM1,CD47,PIK3CA,IL17F,MIR15A,ZFAND2B,LYPD6,P2RY12,ROCK1,PDCD4,NEO1,MIR373,MIR183,TLR2,CYP1B1,DMPK,DUSP9,CLEC12B,CTNND1,CYRIB,TBK1,PPIF,CSNK1A1L,DIRAS1,NUP62,JMJD8,MAPKAPK5,WBP2,PDE2A,NHERF1,NPSR1,MAP2K6,NPPC,SYP,CCL2,DUSP6,PSD2,OPRL1,PIH1D1,DRD1,MIR16-1,ACVR1B,TXNDC12,CD40,ARFGEF1,TMBIM6,SYK,FGF16,BFAR,CREB3,STK11,CCAR2,TRIM5,RGL2,FBXW7,HDAC6,ZDHHC17,S100A8,NOG,PRR5L,KCTD10,MIR101-1,SCYL2,SPTBN1,KBTBD6,EGFL7,LACRT,DUSP1,BIRC2,TRIM32,SH2D1A,OCIAD2,MCL1,LEPROTL1,PLCB1,TLR9,HDAC3,CDC73,TNIK,TMEM204,MIR96,PPP1R10,NACC2,SEMA4C,MIR204,CLEC6A,SAR1B,SIPA1L1,PEX5L,NMI,EDNRA,DSTYK,WNT10B,MAD2L2,GPR65,SLC35C1,HHIP,UCN,LPAR2,VPS18,OPTN,CNRIP1,CD80,FAM89B,AKT3,ERRFI1,MIR1224,PPP2CB,GPR137,TMBIM1,CDC42SE1,OR2AT4,DAPK3,PRNP,SPRY1,HAX1,IQSEC1,GRAP2,ELF1,UBE2K,DDX1,KPNA1,MOSMO,MMP14,MIR223,TMEM100,DNAJC27,PTP4A3,ASPM,GNAQ,PYDC2,ACAA2,CD86,MMP9,GADD45G,PADI2,TRAF3IP2,BAX,AGPAT1,NDST1,EFCAB7,MOB3B,IL6,PATE4,FAS,PID1,KIT,XBP1,TSPAN5,MET,DLK2,AR,UBE2D1,SOD1,CAAP1,TGFBR2,MIRLET7B,MIR130A,PAK2,NR1H2,MIR125A,FGF1,PLA2G5,RPGRIP1L,PCSK9,NRP1,PIP5K1A,TFG,PPP3R2,TSG101,PPP5C,RGMA,PARL,MIR10B,SYVN1,CDK5RAP3,GLCE,PRKCE,TMEM88,AKT1,SIAH2,TGFB3,IL1B,MIR182,WNT7A,HERC4,PPP3CA,ARFGAP1,RPL26,SLC25A31,GPC1,DUSP26,AGR2,TLR6,TMED4,FBXO9,MIR675,SIRT7,CALR,TAX1BP3,LPAR6,NFKBIA,IGF1,CIBAR1,SAP30,SGMS1,SPRED1,CNOT2,UBE2W,KICS2,INPP5E,MT3,RGS5,RBBP4,GH1,TNFAIP3,GID8,GSTP1,VDR,BAK1,TXN,PPP2R1A,NREP,SUFU,HOMER3,IRAK4,TNFAIP8L3,KLHL22,HELLS,TRIM52,F10,UFL1,FCMR,MIR212,SLC15A2,MLF1,MIR503,RBCK1,CYP27B1,TRIM44,TRIM15,SIAH1,LGALS3,HINT1,C1QTNF1,S100B,ATAT1,MIR198,FAF1,MIR195,GHR,PTPN1,LAMB2,HSPA8,ARHGAP1,TMEM33,ACKR3,ITGAV,MIR26B,PCGF2,JADE1,SEC14L1,DLG4,CER1,RPS15,IFI6,TLR4,APLNR,HOMER1,TMEM14A,ZBED3,PIP4P1,CRBN,STK4,TP53,SDCBP,TNFSF10,KCTD12,MDM2,DDX5,SOD2,NEK7,TNFAIP6,MIR1-1,AVPI1,SOST,SYNJ2BP,MAP3K3,CASTOR2,NLRP3,GJA1,MIR17,MIR214,YWHAB,CSNK2B,CTSD,LYNX1,ARF6,IRF4,TIFA,TMSB4X,MDFI,FOLR1,LSM14A,TBC1D10C,GNG7,TNFAIP1,GPR89A,SLC25A5,NPY5R,NLRP2,GREM2,PTPMT1,RB1,CITED1,ILK,RNF152,CASP4,EID2,PFDN5,CTDSPL2,HFE,BCL6,RHOU,CXCL12,FGF7,STUB1,LURAP1,MZB1,CHRDL1,DUSP10,TBC1D24,MIR98,EMILIN1,ARHGAP12,HECW1,FBP1,CX3CL1,BRMS1L,RBPJ,MUL1,FGF3,TWSG1,TNF,PDIA3,RUVBL1,ING1,EDA2R,PHB1,RPA2,AVPR1B,SLC25A4,TESPA1,SEC13,MYD88,GADD45B,NPTN,IL4,OPHN1,HTRA2,CYTH1,TMEM127,BEND6,HSPA5,SOCS5,LDLRAD4,ATP2C1,CD81,MIR146A,TULP3,MIR149,FXN,CD46,IGFBP3,MAVS,DEPDC1B,CSNK1G3,TMEM101,FURIN,DOK4,EEF1E1,CPTP,LANCL2,ANAPC15,GPR35,DKK3,CDKN2AIP,RUVBL2,ING2,STAMBPL1,MAD2L1BP,SWAP70,MYORG,IL12A,SCG2,REN,MIR132,BCL10,TEDC2,TPD52L1,RWDD3,FRZB,HNF1B,CCL3,MIF,OPRM1,RNF34,FBXO8,STK3,IL6ST,CSF2,BTN2A2,HEY2,MAP3K12,IRF3,AKAP12,DYRK2,EPHA4,TRIM68,TLR3,UBAC2,SPEF1,RGS19,CCL5,CDC42,PPIA,DUSP19,SOCS2,NUPR1,CSNK1E,IFT172,FERMT2,MIR302B,FLCN,SFRP1,IGF1R,CBL,NDFIP1,SOX9,STAT2,ANKRD6,RHEB,HCST,IL1R2,PROK1,CSNK2A1,GHRL,RGN,BANF1,DNAJB9,DLG1,CHST11,IGBP1,SNAI2,BECN1,CBLN1,LTBR,FIS1,DICER1,CYTH2,ING5,PELO,DHX15,KDM1A,IL5,SLC38A9,GRAP,FKBP1A,MIR29C,TLR7,NUCKS1,WDR11,IGFBP4,SAP30L,HGS,PRMT2,CCR1,MAP2K1,DKK1,GLRX2,FAM20C,RABL3,FEM1B,GAS8,CA8,COL3A1,C9orf72,RNF167,HAND2,ADRB2,HCFC2,SEMA5A,CCR7,ISG15,SETD9,MAP2K3,DUSP3,MIR346,FRRS1L,SHISA2,TLE1,MIR9-1,TRIM8,OTUD7B,LTB,SESN3,RAB29 |
| 1.326e-15 | -34.26 | CDK7 (cyclin dependent kinase 7) | protein interactions | 1022 | 487 | 218 | 19454 | 5460 |
RPL6,QPCTL,YWHAH,YWHAG,YWHAB,DYNC1I2,SNRPA1,SNRPD3,LYAR,ECHDC1,HSP90AB1,DHX38,RANBP1,SUPT5H,PI15,EEF2,H1-3,TUBB4B,RPL18,LSM14A,RTCB,RUVBL2,CDK5,TRIM21,VDAC1,HNRNPF,KRAS,ZBED1,RPL28,PSMA4,HNRNPC,CREBBP,RPL39,FTSJ3,H1-10,CCT2,POLR1B,H1-1,DLST,MCPH1,PRMT5,ATP5F1B,PSMD4,SSH3,RPL10,POLR2B,MED31,EIF4B,XRCC5,SNRPA,EP300,HSPA8,EEF1G,PHB2,SLC31A1,GOSR1,TMEM177,LYPLAL1,TPM3,GAPDH,RPL10A,RPS2,ALYREF,SDHB,EEF1B2,CDK6,VTI1B,RPS16,SURF6,LMAN1,TMPO,MYL12A,TP53,RPSA,SNAP29,BMPR2,CAPZA2,TAF2,GFM2,SLC25A11,ATP2B4,MAP1B,SLC16A1,TMEM33,HNRNPK,PSMA5,MNAT1,RPL17,RDH11,RPL7A,CCNB1,SUB1,SLC25A1,RPS3,GTF2H2,SEC61A1,SRPK2,GTF2H4,SPTBN1,CCNH,SDCBP,RPA2,CYC1,PML,RPL27,PRDX6,EXOSC4,STK38,HSPA5,PRDX1,PRPF19,TAF7,HNRNPA1,UBE2D1,RPL23,SLC25A21,CDKN1B,PHB1,RPL8,RPLP2,RPL7,CCAR2,DHX15,CETN2,PPIA,VDR,GTF2E2,HOXB1,RPL29,RPS11,RBPJ,HSPD1,SLC25A5,PCNA,KCTD17,ETFA,CDK20,LASP1,SSRP1,PCGF6,GTF3C3,TMED7,MCM3,PRPF31,LMNB1,BRCA1,YWHAZ,RIT1,HSP90AA1,RPS5,CYB5R3,RPS9,CDC7,SPINDOC,TUBB,MED17,RPL35,TAB1,RPL19,ERH,SNRPB2,WDR77,MYL6,SLC25A3,GTF2H5,HADHA,COIL,STX7,FNDC11,ERCC3,GTF2E1,MED21,BRD3,RPL12,H2AZ1,TRAK2,RPL35A,CDK9,TOMM70,MTA3,RPL15,SMAD1,DDX39A,EEF1A1,NDUFS3,TMEM94,RAD23B,SFXN1,SLC25A10,EMC2,PC,RPL23A,THRAP3,PRDX4,RPS13,AR,NONO,ATP5F1A,NAPA,OPTN,RPS20,GANAB,CAB39,PPM1M,RPL13A,SLC25A4,RPL22,EEF1E1,UBA52,RPS14,CDK7,CCNA2,CDK1,RPLP0,RPA3,MTDH,TCEA1,RPL4 |
| 1.336e-15 | -34.25 | SRSF1 (serine and arginine rich splicing factor 1) | protein interactions | 6426 | 546 | 239 | 19454 | 5460 |
XBP1,CDC42,ZNF326,SSR1,WWP1,WRAP53,LUC7L3,ACACA,DDX46,RNF113A,RPS15,TOMM20,SUB1,RPL7A,SMARCA5,RPF2,RC3H2,UBE2H,ELAVL2,DTL,RPS3,SF3B6,RBMX2,PHAX,MRPS21,DYRK1A,RSL24D1,SRPK2,SMURF1,TP53,IMP3,NHERF1,RBM34,IK,SURF4,NUPR1,SNIP1,DHX9,RPL3,IMP4,HNRNPK,RPL17,SRSF12,MEPCE,RBM17,COPS5,SNRNP70,CHCHD1,BCL10,USP15,NOL12,CDK12,ALYREF,RPL32,SYNCRIP,MRPS9,CDK6,FZR1,CAND1,CDC5L,SURF6,TMPO,MBD5,ILVBL,DKC1,MTF1,PABPC5,TRMT112,SNRPA,DDX5,EP300,HDAC5,SF3B1,HSPA8,STAU1,TRA2B,HNRNPA0,SRSF2,UFL1,MRPS7,SAP18,HNRNPC,SFN,MYC,SNRPB,SLC30A5,BTF3,CXCL1,FTSJ3,H2AZ2,NSA2,H1-1,CMTR1,SMU1,SF3B4,MATR3,PAIP2B,NCSTN,ISG15,TRAF2,SMNDC1,PABPC1,TOP2B,EWSR1,SATB1,NUP42,KRAS,H1-6,HNRNPF,HNRNPDL,CBLL1,WWP2,DDX50,IFI16,DDRGK1,NGDN,XPO1,YWHAG,YWHAH,MAGOH,SRSF1,FABP5,CLK4,EED,LYAR,SNRPD3,SNRPA1,RPS10,SF3A1,SLC12A2,METTL14,LMNA,ZNF574,RPL26L1,RPLP0,HNRNPH3,PRPF4,CLK1,NUCKS1,RPL4,HMGB1,FBXW7,AATF,PIAS1,AR,PPP1CC,TRAF3IP2,PPIG,CASC3,EIF4A3,CCNF,UBE2I,CMBL,PRKRA,GSK3A,MAGOHB,NDN,GNAI2,UBB,FBP1,RPL15,FCF1,CD2BP2,UBE2B,APEH,ILF2,NKRF,FAF1,EMC2,SNAP23,THRAP3,HUWE1,PAK1IP1,MSH6,MDC1,MRPS18C,SPATS2L,MOV10,MPG,ZMYND11,HDAC6,MPHOSPH10,BRD3,KRR1,RCHY1,TOP1,THOC1,CWC15,AKAP17A,H1-5,LARP4B,USP39,PPARG,NKAPD1,UPF3B,CCDC86,NOP53,NOP16,CUL2,CUL3,NFYA,ZNF668,NOA1,BRCA1,RIT1,ZNF22,SNRPD1,SNRPD2,RPF1,RPL7L1,SNRPB2,TNPO3,RPL19,B3GNT2,RAF1,MAK16,EZH2,SNRPE,SF3B5,ARGLU1,HSPD1,SRSF7,MRPS11,RPS24,AHCYL1,SRSF4,RPS27A,MRPS35,PIK3R1,PRPF19,TRA2A,HNRNPA1,PHB1,FOLR1,RPL8,RPLP2,IGBP1,DHX15,SRSF10 |
| 1.464e-15 | -34.16 | regulation of response to stress | biological process | GO:0080134 | 1431 | 556 | 18204 | 5365 |
CLDN4,INO80C,CXCL12,BCL6,MBL2,ABHD17A,FEM1A,DDAH1,STUB1,HMGB1,BCL7B,CD1D,TOP2B,DUSP10,CD226,HRAS,PLG,PYCARD,MIR361,AGER,CXCR4,TBC1D24,EMILIN1,IL10,ROCK2,MUL1,XCL1,CX3CL1,MIR1298,ADIPOQ,TNF,CAMK2N1,ACTB,DDRGK1,TRIM6,LY96,RPS3,PHB1,RPA2,VAMP7,RUVBL1,MIR145,MSX1,CEBPG,EIF4E2,NLRP3,MIR214,MIR17,TMEM126A,MAPKAPK3,BCL7C,MIR657,PLSCR1,IRF4,FUT8,TIFA,CCR2,F2,FOXC2,CLDN3,MIR105-1,CDK9,HAPSTR1,TMSB4X,LSM14A,VAMP2,PSMD10,OGG1,NLRP2,NPY5R,RB1,GGT7,CGAS,ZNF365,RAG1,H2AX,CASP4,HSPA8,ADORA1,PTPN1,MIR26B,PRDX2,MGMT,TMEM33,ACKR3,CHORDC1,EYA3,TLR4,TFPT,SEC14L1,DNAJC2,NONO,MIR590,PTPN11,TOMM70,ST3GAL4,MICB,KLF4,CTSC,TP53,IDO1,FADS2,TAF7,MDM2,ACTL6B,IL13,DDX5,MIR34A,NEK7,IL21,CLEC7A,VPS72,TNFAIP6,IRAK4,ZNHIT1,TNFAIP8L2,SESN2,STK24,UFD1,MLC1,SGTA,PTGER4,CSNK1A1,SLC15A2,PPARG,UFL1,TRIM44,CNOT7,TRIM15,IKBKB,C1QTNF1,EPO,DROSHA,ATAT1,MIRLET7G,YTHDF2,MIR195,MIR25,SPP1,DYRK1A,FEM1B,DHX9,VAMP8,TRAFD1,PTPN22,USP13,HCFC2,GREM1,CREBBP,ADTRP,CCR7,KLK3,ISG15,RNF8,MIR144,KLHL15,FCN2,CLPB,IL1A,TGFB2,SVIP,NCK1,FBLN5,SPRED2,PCNA,SESN3,FGF10,NDFIP1,STAT2,TNR,FAM3A,CSNK2A1,TADA3,MIR20A,GHRL,TRIM22,SLC25A14,SF3B5,IGBP1,BANF1,DNAJB9,IFI35,SNAI2,BECN1,MIR708,MACROH2A1,KDM1A,USP14,NLRP6,TLR7,IRF7,CD200R1,ATP2B4,MIR200C,TRAF3IP3,OAS1,CCDC92,RNF126,FCGR1A,COPS5,MIR488,MAP2K1,LTA,ELMOD2,LILRB1,IL12A,HTR2A,MIR132,DDT,BCL10,CCL3,MIF,OPRM1,RNF34,HSP90AA1,IRF3,USP15,IL6ST,LRRC14,PHF13,TLR3,EPHA4,GPSM3,CCL5,CASK,MIR142,APOBEC3G,PTGES,NUPR1,GPR17,PPIA,IGF1R,MIR126,IER3,FERMT2,MYC,MIR31,TAF5L,ABHD12,BRCA1,IL4,MYD88,TAF2,HSPA5,IL20RB,SOCS5,GFI1,ZMPSTE24,MIR208A,IFIH1,CD81,MIR146A,ARL6IP5,PTN,HBEGF,NLRP9,CLDN1,MIR149,APOBEC3F,MEAF6,FURIN,MAVS,TAB1,IFNB1,TRIM11,CPTP,CAV1,SOCS3,TYROBP,EEF1E1,RUVBL2,ING2,LYPLAL1,SUPT7L,MEF2C,TAX1BP1,CD28,TADA1,CMA1,FKBP1B,CDKN2D,ARFGEF1,OTULIN,TMBIM6,TXNDC12,BFAR,NLRP1,SYK,CLU,MIR205,CCAR2,PSMA1,TRIM5,STAP1,CREB3,HDAC6,SGF29,S100A8,FCGR2B,NFKBIL1,FBXW7,CERS2,SMAD3,SLC7A11,SARM1,NT5C2,SELENOK,BIRC2,YES1,TRIM62,MIR920,PIK3AP1,KMT5B,TAF9,CRHBP,KLRC2,RHBDD3,CCN3,TRIM32,TICAM2,MIR222,SLC12A2,TLR10,TRAF6,TLR2,CLEC12B,DNAJC7,THBD,NINJ1,XRCC5,RNF26,TBK1,TLR5,VAMP3,TMEM97,PDE2A,PML,FAM168A,PSPC1,CHCHD2,IL2RA,TASL,MAP2K6,ALOX5AP,EFHD1,SUPT3H,KCNJ8,SPATA2,MIR16-1,NFKB1,MIR141,ARG2,PSMB4,WRAP53,SRC,MIR34C,IL18,PRDX1,LEP,HNRNPK,SQSTM1,INSIG2,THY1,PIK3CG,CD200,NECTIN2,MIR140,TRIM21,SLC25A23,FGL2,PHB2,HEXIM1,TFPI,IFNG,SERINC3,F7,CD47,TAF10,IL17F,MIR34B,MIR15A,LGR4,NEO1,TRIM45,PDCD4,YWHAZ,CCL1,OSM,IRF1,TRIM3,PQBP1,SETD4,PIK3R1,ZNRF1,ACTR2,NBN,BPIFB1,TFIP11,SERPINC1,AREL1,TLR8,IFI16,DEK,SMARCB1,PPM1B,MIR181C,IL15,TICAM1,NFE2L2,TLR1,UBASH3B,MIR29A,RNF115,SAMHD1,SEMA7A,SLC38A2,IL23A,IL1B,NOP53,AKT1,PPP3CA,UBE2V2,UBE2V1,LMNA,SELENOS,INO80E,RPL26,AGR2,TLR6,RADX,NCR3,SIRT7,KARS1,BOK,GRPR,ABCB1,SPRED1,PDCD10,ENY2,EP300,NFKBIA,IGF1,GPX1,KLK5,CCL24,HYAL2,SHLD1,GSTP1,BAK1,TNFAIP3,IL22,MIR206,CD14,FAS,EIF2AK2,XBP1,CNR1,KLRD1,SOD1,UBE2N,IL2,MIR221,PAK2,PLA2G5,TIRAP,MIR187,ACP5,TTI2,STAT1,NR1H2,JAK2,PTEN,MCPH1,MORF4L1,BCL2L1,SMCHD1,BAD,RGMA,DEFB114,CRY1,PRKCE,SYVN1,LACC1,DMAP1,VDAC1,MATR3,CD274,FOXP3,LDLR,ENO1,HSPD1,ACTL6A,PSMA6,SMARCE1,FLOT1,PPARA,PELI1,PPP4C,IL12B,UBE2K,FGR,POLR3B,DUOXA2,MIR223,FOXP1,MACIR,PYDC2,MMP9,RSAD2,IL6,TRAF3IP2,BAX,ERP29,USP38,ENPP4,SH2D1A,PROS1,MGST2,RTN4,TNFRSF1B,SMARCD3,TLR9,IFNK,PPP1R10,FABP4,MIR21,LPCAT3,MIR96,CD9,SFN,DNAJB6,AQP11,SELENON,SEMA4C,LILRA2,NACC2,NMI,CLEC6A,MIR204,SERPINB9,RIGI,SIN3A,LYAR,MAD2L2,CASP12,RMI2,CD36,BABAM1,TPT1,PNPLA8,UCN,PMAIP1,POLR3F,BAP1,MIR210,OPTN |
| 1.596e-15 | -34.07 | regulation of apoptotic signaling pathway | biological process | GO:2001233 | 396 | 191 | 18204 | 5365 |
PLEKHF1,CCAR2,CREB3,PYCARD,S100A8,FCGR2B,NOG,RPS7,NKX3-1,FBXW7,ATF3,TMBIM6,TXNDC12,CXCL12,CLU,RPS3,PDIA3,MSX1,DBH,TRAF2,CX3CR1,TRIM32,TRAF1,TAF9,SLC25A4,IL10,CX3CL1,RAF1,TNF,PPIF,MIR222,ACVR1,MIR17,RB1,CTTN,PTPMT1,STRADB,SLC25A5,MIR16-1,TERT,CRADD,PIH1D1,PML,PSMD10,BMPR1B,NHERF1,IFI6,TLR4,EYA3,DDIT3,HNRNPK,NONO,ATF4,GHITM,TMEM14A,PTPN1,SRC,PRDX2,RB1CC1,PCGF2,MIR26B,ITGAV,ACKR3,FGFR1,TNFSF12,FAIM,MIR15A,SOD2,PRKRA,ITGA6,TP53,CTSC,SERINC3,STK4,ICAM1,MDM2,TNFSF10,PPP2R1A,HELLS,MIR198,IL7,PYCR1,MIR195,FAF1,SIAH1,IVNS1ABP,PRELID1,RBCK1,FBXO7,EPO,NFE2L2,NR4A2,LGALS3,SLC25A31,SELENOS,RPL26,TLR6,FEM1B,IL1B,SIAH2,AKT1,LMNA,GCLC,ZMYND11,NCK1,GPX1,BAK1,GSTP1,HYAL2,CTSK,TNFAIP3,FGF10,CTNNB1,LTB,BOK,IL1A,VDAC2,SGMS1,IGF1,SLC35F6,SOD1,AR,RRN3,PAK2,FIS1,MIR221,LTBR,CAAP1,BECN1,SNAI2,GNAI2,CTNNA1,FAS,CSNK2A1,AATF,XBP1,PARL,G0S2,BAD,SYVN1,NRP1,KDM1A,ING5,JAK2,BCL2L1,STK3,TRAF7,PAK5,RNF34,TMBIM1,USP15,MIR449A,CSF2,PELI3,TPD52L1,BCL10,ENO1,MIR132,SCG2,MIF,MIR186,NUPR1,HSPB1,UBB,MIR142,PPIA,MMP9,ACAA2,IER3,FLCN,SFRP1,ERP29,MYC,BAX,PEA15,PSEN1,MIR21,FXN,NACC2,BRCA1,MCL1,HTRA2,ING2,NDUFS3,TPT1,CDKN2D,MIR210,PMAIP1,CAV1,IFNB1,EEF1E1 |
| 1.664e-15 | -34.03 | UBC (ubiquitin C) | protein interactions | 7316 | 1220 | 466 | 19454 | 5460 |
TOM1,SEM1,PRDX4,SOCS2,RNF20,GLUL,PC,UBE2B,JOSD1,RNF181,RAD23B,SMAD1,POP5,ING1,MAP1LC3B,MAPRE2,KLF1,CAV1,ATP5PD,RCHY1,EEF1AKMT3,H2AZ1,CLN8,HSD17B11,PSMD7,TIAM1,HDAC6,HMGB1,PFKFB2,USP8,DESI1,GTF2I,SLC5A6,PRPF4,NCDN,SQSTM1,RPLP0,B3GALT1,PSMC4,ATG16L1,HACD2,LDHA,RPL22,OPTN,STUB1,RPS20,PTEN,CHCHD6,UBASH3B,CAP2,TUFM,USP14,ATP5F1A,TRIM26,G3BP1,RFC3,RFC2,TRIP4,UBE3A,FHL3,CFAP36,EZH2,OTULIN,AP2S1,RNF126,TXNRD1,LGR4,GFPT1,CYB5R1,KCTD10,LRWD1,NDUFS8,CACYBP,ERLIN1,PHB1,TSG101,XPO5,PSMD10,TRAF6,UBE2D1,CDKN1B,DPY30,STOML2,MRPS35,CDIP1,UBXN6,PRDX1,PSMD3,PRPF19,MAP3K14,GPC1,NSFL1C,NPTN,G3BP2,SKP1,PSMC1,WBP2,CXCR4,RLIM,HADHA,HACD1,PPARG,ATP5PO,WDR77,PPP1CB,PRDX3,RBBP4,RPL7L1,CHP1,OTUD6A,CHCHD3,CYB5R3,UBE2S,ARF1,AP2M1,LMNB1,MYO6,BLVRA,FAS,CBR3,CUL3,CUL2,GRB10,USP13,SOCS5,OTUD7B,RFC5,TOLLIP,RBCK1,SRPRB,FKBP8,THG1L,TRAFD1,MRPS18B,NFE2L2,RNF8,PSMC3,TAB2,MTCH2,TNRC6C,UBL4A,ACTR1A,H2AX,FCHO2,ARMC1,EEF1B2,SYNCRIP,BECN1,TUBG1,USP15,DNAJB2,PPM1D,ZFAND2B,CSNK2A1,COPS5,UBE2K,MARS1,HSPA5,TOMM20,PRDX6,SDCBP,RPA2,HECTD1,ACACA,TRIM36,HEXIM1,GSTP1,SUMO1,TRAM1,ADRM1,TRAF1,SMURF1,PSMA6,FKBPL,RPS3,SGTA,PSMC5,RC3H2,TRIM23,ZFAND6,RAP2C,ATP1A1,RSPH1,TNFAIP3,VDAC1,FGD2,RPL28,PABPC1,CCT8,RBM3,RUVBL2,UCK2,KLHL12,TRAF2,CCDC134,TCP1,DYNC1I2,SDC4,SRSF1,ZHX1,AGR2,IKBKB,R3HDM4,DCAF5,HSPB1,DRG1,YWHAB,STAMBPL1,UBE2E2,TNFAIP6,TBC1D5,UBE2D3,HNRNPA0,RNF5,MRPS7,DDI1,XRCC5,SNRPA,EP300,YAF2,TIFA,APPBP2,HSPA8,UBAC2,PLAA,YIPF5,HECW1,SNRNP40,PSMD6,PSMD4,TCEAL1,USP16,USP38,TOM1L1,TRIM44,ANAPC2,RBBP8,DNAJB6,GFUS,MLF2,PCCB,FARSA,ANAPC11,RNF115,HUWE1,RIGI,PSEN1,TCOF1,FAF1,ACTR2,NDUFS3,TOPORS,CCT5,FBP1,UBE2V1,EXOSC8,TSC22D3,ASB11,DCUN1D1,MDM2,RPL12,PSMB1,DECR2,DLGAP4,MUL1,OSBPL8,MOV10,FBXW7,VPS28,PIAS1,INPPL1,RPA3,SOD1,PPIH,PRKCB,STOM,METTL14,WTAP,UBAP1,RARS1,STAMBP,UBA52,CDK7,UQCRC1,COPE,VIRMA,UBE2L3,UBB,CCNF,PTCRA,RPS12,TRIM27,HERC4,ANKIB1,AP2A1,CDC73,TRAF3IP2,FBXO7,BRAP,DHX16,TNF,FLOT1,COPS4,RAD21,UBE2A,PSMD12,RPS27A,HNRNPA2B1,MAEA,HSPD1,BAG2,OPA3,PCNA,RPN1,SART3,POLR2C,RPS11,RBM12,DCAKD,ERLIN2,JUN,FAF2,OTUD6B,PPP2R1A,DHX15,PSMB5,KLHL7,RPL9,USP46,RPLP2,MAP1LC3A,PEDS1,CDK5RAP3,HNRNPD,HAX1,RB1CC1,VCPIP1,ISX,PTPN5,VPS26A,BABAM1,PIK3R1,CISH,UCHL3,RNF11,PSMA3,BIRC2,TXNL1,TRIM5,PSMB7,VAPB,ARCN1,PLSCR4,TOR1AIP2,ACTL6A,DET1,MYH1,RNF182,TAB1,PRDX2,USP5,UBE2V2,RPS9,BRCA1,YWHAZ,OPRM1,HNRNPK,PDE12,RHBDD3,NEDD8,PSMA5,MEPCE,ZNF451,DHX9,ZNRF1,MINDY3,TP53,CAND1,VCPKMT,CD2,CHGA,UBTD2,UBE2N,UBE2G2,ALYREF,H2AC4,RPL24,CCDC92,MAP4,AREL1,USP2,USP3,ELOC,RGS2,CLU,UGP2,PML,BAP1,LSM12,WWP1,FGFR1,RAG1,CD2AP,CDC42,AGO1,MAP3K3,ACP2,CDC20,IDE,SEC61A1,UBE2E3,UBE2H,UNC79,TRIM32,PSMB2,AKT1,FBXO44,BFAR,RUVBL1,XPNPEP1,FOXN2,PSMA2,HNRNPF,PSMA1,USP30,PELI1,FAM168A,TRIM21,PDHA1,HGS,EEF2,NUP37,TUBA1A,SUMO2,SUMO3,RNF144B,CDK17,HNRNPL,HSP90AB1,CCT7,RIMKLB,UBFD1,CBL,WWP2,YWHAG,ADRB2,ITGAV,HERC3,SPECC1L,TMEM160,TAPBP,GTF2IRD1,TOM1L2,TAX1BP1,PCMTD1,MATR3,PSMB6,DLST,LMBR1L,PSMD14,CCT2,COP1,HNRNPC,LDHB,UFD1,PSMD1 |
| 1.781e-15 | -33.96 | structural constituent of ribosome | molecular function | GO:0003735 | 164 | 98 | 18094 | 5411 |
MRPS16,RPL27A,RPL7A,MRPL13,MRPL20,RPL6,RPS12,MRPL23,RPS17,MRPS35,RPL7,MRPL34,RPS29,MRPL24,RPL22,RPL4,RSL24D1,MRPS33,MRPS11,MRPS17,MRPS9,RPS16,RPL10A,MRPL33,MRPL12,RPL15,MRPL16,RPS11,MRPS18B,RPL9,RPL35A,MRPL11,MRPL9,MRPL49,RPL28,RPL26,RPL17,RPL39,MRPL10,RPL10,RPL29,RPL13A,MRPL22,RPS27A,RPL18,MRPL41,RPS4X,UBA52,RPLP0,RPL23A,FAU,MRPS23,RPS13,RPS28,RPL8,MRPL57,RPL31,MRPL51,MRPL18,RPS7,RPS3,RPL10L,RPL32,RPL24,RPL12,MRPS18A,RPS10,MRPL36,IMP3,RPSA,RPL23,RPL7L1,RPS26,MRPS34,RPS15,MRPL52,RPL19,RPS23,RPLP1,RPS5,RPL26L1,RPL3,RPS20,RPS9,RPL37A,MRPS7,MRPS18C,RPL27,MRPL17,RPS27L,MRPS21,RPS2,RPS24,RPL35,MRPL47,MRPS25,RPLP2,RPS14 |
| 1.798e-15 | -33.95 | METTL14 (methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit) | protein interactions | 57721 | 550 | 240 | 19454 | 5460 |
PPIB,RPL6,DRG1,DDX1,MAGED2,SRSF1,CCT7,HSP90AB1,SNRPD3,TCP1,RPS7,EEF2,ETFB,RPL18,TUBB4B,PDIA6,EWSR1,ABCF1,TOP2B,CCT8,RPL31,CBLL1,HNRNPDL,RPS4X,VDAC1,KRAS,HNRNPF,SNRPB,BRMS1,PSMD1,PSMA4,HNRNPC,LDHB,HNRNPAB,SERPINH1,COP1,RPS26,CKB,CCT2,PRMT5,SF3B4,VDAC2,APEX1,NCKAP1,RPL10,PSMD6,PSMD4,ATP5F1B,MATR3,PSMB3,EIF4B,DDX5,HSPA8,XRCC5,DDX39B,PHB2,EEF1G,SRSF2,UFL1,ELOC,GAPDH,TPM3,CSNK2A1,COX5A,EDEM1,RPS2,AKAP8L,SNRNP70,RPL24,H2AC4,ALYREF,SYNCRIP,STT3A,IAH1,TMPO,PLG,RPS16,H2AX,RPSA,GNAI3,CBX3,TFRC,DHX9,ABCE1,SLC16A1,RPL3,RPL17,HNRNPK,CHDH,CFL1,SUB1,PTPN11,RPL7A,PDCD4,SERPINB1,MACROH2A1,INTS12,EIF2S2,PSMC5,GNAO1,PSMA6,RPS3,BUB3,CFTR,SPTBN1,CYC1,ACACA,SSR1,HPS6,DLAT,BANF1,NLE1,DDX46,RPL27,CLU,HSPA5,HNRNPA1,STOML2,PDIA3,PSMD3,PRDX1,RPL23,PDCD10,HNRNPD,AHSA1,KRT8,RPLP2,PHB1,RPL9,RPL8,PPIA,SRSF10,CCAR2,SPTAN1,RPL7,NOP58,SNRPE,RPS11,RPN1,SRSF7,SRSF8,BAG2,SLC39A7,ARB2A,HNRNPA2B1,SLC25A5,HSPD1,MCM6,PSMD12,G3BP1,RBBP7,MCM3,MCM4,CUL2,PMPCA,RIT1,RPS5,HSP90AA1,LMNB1,RPS9,SNRPD1,SNRPD2,SNRPB2,RPL19,GGPS1,ACTB,RPL35,TUBB,RANBP6,PRDX2,ETF1,PRDX3,WDR77,MYL6,SLC25A3,H2AC1,PSMA3,ATP5MK,G3BP2,PSMC1,CALR,EIF5A2,HSD17B11,H2AZ1,SMAD3,RPL12,G6PD,SLC25A12,RPL35A,EXOSC8,RPL15,EEF1A1,CCT5,ILF2,SEPTIN7,H2AC25,RIGI,H2AC6,RPS13,THRAP3,HSPE1,LSM4,HUWE1,NONO,TUFM,RPL26,ATP5F1A,CTSD,AP2A1,SMAD2,MSN,ALB,TRIM24,RTRAF,GANAB,ENO1,STUB1,RPL22,DEK,GNAI2,VIRMA,TECR,TXN,LDHA,SEC22B,RPS14,WTAP,KRT7,RPLP0,METTL14,HSP90B1,COX6C,JUP,LMNA,H2BC12,RTN4,BRIX1,SMC4,RPL4,PDHB |
| 1.972e-15 | -33.86 | STIP1 (stress induced phosphoprotein 1) | protein interactions | 10963 | 960 | 380 | 19454 | 5460 |
RPL3,KPNA2,FKBP8,RRM1,MTCH2,IPO8,ACTR1A,TFRC,TFCP2,ACVR1,PSMC3,TBC1D4,AIP,SYNCRIP,CD274,COQ8A,AKR1B1,RPS16,TMPO,DKC1,CDC5L,KARS1,DNAJB2,FAM20C,CSNK2A1,TUBG1,RPS2,RPL10A,PRDX6,KDM1A,HSPA5,MARS1,SPTBN1,NTPCR,RPA2,ZNF326,SAMM50,UBE2M,ACACA,HECTD1,RPS3,TSSK1B,PSMC5,EIF2S2,SGTA,BUB3,CSTF3,RPF2,MAT2A,PTPN11,RPS17,H2BC9,SLC6A4,EIF3G,DNAJC10,ATP1A1,PABPC1,TOP2B,CCT8,DNAJB4,RPAP3,RUVBL2,PDIA6,VDAC1,HNRNPDL,SOX2,KIF2A,MTA2,FABP5,SRSF1,MAGED2,ADCK1,EIF2S1,DYNC1I2,TCP1,AGR2,FKBP4,HSPB1,SNRPA,XRCC5,HSPA8,EP300,STK26,AKAP1,HNRNPA0,STAU1,EYA3,RPL27A,NUP62,ADSS2,PIH1D1,SF3B4,ANAPC2,ATP5F1B,PSMD6,SNRNP40,PPP5C,LMO2,MLF2,LAMTOR1,DNAJB6,SEPTIN7,HSD17B10,TAGLN3,HINT1,HSPE1,RPS13,OLA1,EIF3E,TBK1,LBR,RPL15,ILF2,HACD3,AIFM1,EEF1AKMT3,SEC23A,PWP2,PRNP,EMC4,CDC37L1,HDAC6,LRRC40,GLO1,ESYT1,PSMD7,DNAJC7,PRPF4,FLCN,SQSTM1,GPX4,EIF5B,GTF2I,SMC4,RPL4,PSMC4,SNRPN,CNP,CDK1,LMNA,HSP90B1,PELP1,EIF4A3,RTRAF,PTEN,TXN,YES1,TECR,CSK,PYCR2,AR,KPNA6,NONO,PPP1CC,TUFM,GMPS,TXNIP,XPOT,RPS24,G3BP1,MCM6,AP1M1,TXNRD1,E2F4,NUP153,EZH2,DNM2,THOC2,PHB1,XPO5,IGBP1,NOP58,ATXN10,SNX2,KCTD10,SPTAN1,CCAR2,RPL7,CACYBP,PSMD3,PRPF19,EIF3D,TRA2A,RHOG,AHSA1,RPL23,HADHA,GPC1,PSMC1,FBXL4,UNC45A,WDR77,IDH3B,ETF1,RAN,MTM1,RBBP4,UMPS,CHCHD3,TNPO3,SAMHD1,MCM3,MCM4,LMNB1,DHX9,NUP107,HNRNPK,CSE1L,RPL17,ATP5PB,INSIG2,RPSA,TP53,UBE2N,ADD1,FZR1,CAND1,MYL12A,LMAN1,GAPDH,API5,RPL24,DDX46,BAP1,RPL27,PGK1,ARFIP1,DLAT,WDR3,GRPEL1,CSNK2B,SMARCA5,RPL7A,ST13,DNAJC5,IGF2BP1,UBE2H,RPL31,EWSR1,CDK5,HNRNPF,RUVBL1,CCAR1,RPS4X,TRMT1L,RPS7,EEF2,TUBB4B,PLS3,MOB3C,RPS23,RPRD1A,SIN3A,FUBP3,RPS10,HNRNPL,SUMO3,SNRPA1,SUMO2,CCT7,HSP90AB1,RAB5C,XPO1,YWHAG,CTNNB1,DDX1,PEBP1,DDX39B,SF3B1,DDX5,SRSF2,TRA2B,UFL1,PPT1,PACRG,SMU1,SSH3,TAGLN2,POLR2B,NCKAP1,RPL10,HNRNPAB,PSMD1,UFD1,CCT2,PSMD14,SERPINH1,FAF1,NKRF,RPL23A,HUWE1,NOC4L,PTGES3,CCT5,ACTR2,RPL12,LDLR,PSMB1,CDK9,H2AC14,NME2,HELLS,PRIM2,SOD1,RPA3,IDH3A,CLK1,PDHB,YKT6,BRIX1,METTL14,PICALM,SH3GLB2,RARS1,HNRNPH3,CCNF,PPM1M,MSN,VIRMA,HSPA14,FBXO7,CDC73,SLC25A5,NEK9,HSPD1,SCYL2,BCKDK,SRSF7,BAG2,CDK20,GTF3C3,PSMD12,AHCYL1,RAD21,SSRP1,COPS4,NAA15,ACTN4,PPP2R1A,FAF2,RPN1,PPID,GDI2,CHMP4C,RPS11,POLR2C,SART3,RPL9,RPL8,ATP6V1A,AGK,EGLN3,SRSF10,DHX15,MAP1S,HNRNPA1,WDR12,HNRNPD,HAX1,PSMA3,UCHL3,YTHDF1,DET1,USP39,ARCN1,SLC25A3,ENO2,IFT172,RPS9,ACTB,TUBB,USP5,RAB11A,PYCR1,YWHAZ,BRCA1,RPS5,SCFD1,HSP90AA1,ILK |
| 2.041e-15 | -33.83 | SNRPF (small nuclear ribonucleoprotein polypeptide F) | protein interactions | 6636 | 365 | 173 | 19454 | 5460 |
ZBTB2,NCBP2,POLR2I,THOC1,TOP1,LDLR,ECD,CRBN,SMN1,SNRPG,OLA1,THRAP3,CTNNBL1,TSSC4,LSM4,ZC3H11A,RAD23B,POLR2G,GEMIN7,ILF2,CD2BP2,SH3BGRL,FERMT2,TXN,ZMAT5,EIF4A3,MAPRE1,PPIG,DNAJC8,LSM8,FBXW7,PPIH,PRPF4,GID8,NCDN,LSM2,P3H1,TOX4,UQCRC1,SNRPN,WDR83,SF3A1,ATG16L1,TXNL4A,DHX15,OCRL,IGBP1,PHB1,IFIT2,RPL9,SKIC8,DDX23,TRA2A,ZNF207,HNRNPA1,PRPF19,SSRP1,PPWD1,G3BP1,SART3,SNRPE,GPBP1L1,POLR2C,SF3B5,NGB,CHMP4C,EZH2,RAF1,SNRPB2,ERH,SNRPD2,SNRPD1,RSRC1,RIT1,WDR20,ZCRB1,MYO6,YWHAZ,ARHGAP19,PRPF31,CUL3,CUL2,COIL,PSMA3,MFAP1,FKBP10,USP39,SUPT4H1,WDR77,CDC5L,RBM42,CAND1,ALYREF,SYNCRIP,LSM3,SNRNP70,COPS5,RBM17,MEPCE,CDC40,SNRNP48,DHX9,ABCE1,SNIP1,METTL18,NUPR1,IK,DDX42,BPIFA2,SRPK2,PPP1R10,SF3B6,UBE2H,GEMIN8,LSM6,OGG1,SUGP1,RBM22,BAP1,LUC7L3,UBE2M,TFIP11,ZNF326,RPRD1B,MND1,CDC42,PPP1R8,LSM5,SNRPA1,RHOH,SNRPD3,WDR82,EED,HOMER3,POLR2L,SRSF1,HSPB1,UBFD1,CRTAP,DDRGK1,POLDIP3,HNRNPDL,NUP42,KRAS,EWSR1,CMTR2,RND3,SMNDC1,LSM10,SUPT5H,ESR2,POLR2B,SNRNP40,TAGLN2,SF3B4,PRMT5,SMU1,CHTOP,TTC33,SNRPB,SFN,HNRNPC,MYC,SAP18,ARHGEF39,HNRNPA0,TRA2B,DDX5,SF3B1,DDX39B,SNRPA,PAFAH1B1,ZC3H14 |
| 2.210e-15 | -33.75 | macromolecule localization | biological process | GO:0033036 | 2376 | 866 | 18204 | 5365 |
ROCK2,IL10,CACNB3,ARMCX3,RAF1,ADIPOQ,APPBP2,POLDIP3,DDRGK1,SNX14,RBP5,RAB11A,CNTNAP1,VAMP7,RAB6B,MSX1,RAB2A,STX1A,RAB6A,EMC6,EPHA2,VPS28,PITPNB,ABHD17A,CORO1C,MAPRE2,RHOB,PLEKHF1,AGER,S100A10,TRIM46,CIDEB,ATG3,SH3GLB1,HSP90B1,NETO2,TBC1D13,ATAD1,PEX3,RPF2,SPRN,PSMD10,PLEKHA8,TIMM23,VAMP2,TRIM23,CTTN,STRADB,LGI1,SPCS1,ASIC2,TBC1D5,WDR83OS,RAB9B,TBC1D17,SLC22A8,BRD3,CFTR,LMAN1,PLSCR1,EXOC8,EXOC5,MADCAM1,FKBP8,TMEM30A,BCS1L,SVBP,ERCC3,ARF1,RRAGA,SRPRB,GNPTG,VPS4A,SCAMP5,CHMP1B,RRP7A,ADORA1,COMT,P2RY1,SRSF1,DDIT3,AZGP1,NETO1,TOMM70,AGAP1,CHCHD4,IKBKB,TPBG,SRP54,AP1AR,TRAK2,CLN8,RAD21,CNTN2,OSBPL8,EZH2,UPF3B,RAB32,SLC25A11,CEP41,PGR,GOLGA7B,JUP,CETN3,STX12,RABIF,F11R,GLE1,SPCS2,RAP2A,TMED5,GABARAPL2,UFD1,TSPO,PAQR3,RAB39B,RPL23,YIF1A,CCDC22,PPARG,ARCN1,CYP7A1,DESI1,ANKRD50,LIPA,LIN7C,CHP1,PLSCR3,EMC2,CPT1B,CPT2,SEC22B,FGF10,PEX13,FABP7,EIF2D,TMEM115,SELENOM,TRIM37,ZDHHC24,TOM1L2,SNX33,TIMM10,RBP2,AP5S1,VPS4B,XPO5,RIT2,MACROH2A1,ACTN4,RER1,EDEM1,H2BC11,CCT2,HPS6,TTC8,FABP12,SUMO1,AFTPH,PRKCB,CHGA,AIP,CTNNA1,ARL5B,PLA2G12A,AP5M1,TST,ATP1B1,HYCC2,PREPL,HNRNPA1,THOC2,SEC61G,PMPCA,FITM2,PEG10,DNAJC19,CASK,HSPB1,ZFAND6,GOSR1,FAF2,SLU7,TMSB10,FRMD8,TOMM40,ATP1B3,CDK1,MARCHF5,HTR2A,INPP5K,REP15,SNAP25,GDI2,CNIH4,WDR45,MTCH2,SYNDIG1,HSP90AA1,BTF3,LDAH,SMG5,NECAP2,TNKS,MCOLN1,CAV1,STARD3NL,SUPT7L,PLEKHF2,CAV3,AGAP2,TAX1BP1,RAB1A,NME4,FKBP1B,BLOC1S3,ALKBH5,SNX3,TRAM2,SMAD2,TNPO3,CRB3,MTM1,EGR2,ARL6IP5,TNKS2,PSEN1,ATG9A,CD4,PTN,AP2A1,VAMP5,CD63,GPAA1,PHYHIP,SARM1,ATG16L1,ATG4A,TFRC,NXT2,SEC63,CLTRN,RILPL2,PLSCR4,EIF4A3,RAP1A,ESAM,SRP14,MACROH2A2,UBL4A,TMIGD1,ZDHHC4,CLU,RINT1,GRPEL1,FCHO2,SRPRA,MRPL18,NECAP1,PML,DISC1,FGF13,IGSF11,LAMP5,SSNA1,TERT,KCNJ8,NDP,DNLZ,TSPO2,FXR2,VPS16,NLGN2,SLC25A20,CD2AP,LAMTOR1,ESYT1,RAB19,CUTA,RAB35,C2CD2L,PACRG,SNX10,STX5,SEC23A,CHAMP1,TOM1,ARL4A,RAB8B,SFTPA1,PPID,C1QL3,ANGPT1,DAG1,CDK20,SH3BP4,SLC25A21,SRGN,MGARP,SQSTM1,LEP,RAB40AL,TM9SF4,ZMAT3,PHB2,SIGMAR1,EMC9,MAIP1,MECP2,GOLGA7,FBXO7,AKR1C1,SNX17,LYPLA1,SYS1,TOMM6,KDELR1,SEC61A2,TRIM3,SNX1,ALYREF,SNCG,EHBP1,NBN,SCG3,TMED3,SNX11,AP3S2,STARD4,TOMM7,NPC1L1,CAMK2G,AP1M1,MAGOH,RAB5C,SNX5,RALA,IFT25,CTNNB1,VPS26C,KDELR2,SLC1A1,NOP53,FAM53B,PEX26,LMNA,DRD3,SELENOS,ASB3,VPS26A,GABARAP,UNC50,PDIA2,RNF128,LRP6,TSPAN15,VLDLR,STX7,STXBP1,MCPH1,APOC4,DDX39A,ATP8A1,TUBA1A,RAB27A,BCAP29,SLC4A8,DERL1,CRY1,SPTSSA,FAM91A1,DVL2,RAMP3,TOMM40L,KPNA6,TIMM8A,SEC61B,H2AC4,SNX12,CCHCR1,ATG4C,RIC3,TOR1AIP2,SKP1,TM9SF1,NUP153,ARRDC3,NUP50,LRRC4,COPE,DPP10,MX2,DUOXA2,YWHAG,STOML2,MYO6,CAMLG,ERP29,SEC22C,ROPN1B,AP1G2,HSPD1,LDLR,CPLX3,AP1S2,VPS33A,TNPO2,SERPINA5,SNAP91,FLOT1,TIMM29,RRAGB,MLH3,SIN3A,CHMP2A,CD36,SNAPIN,JAK1,TIA1,GUK1,TSPAN17,EXOC1,EMP2,RTN4,SMURF1,ILDR1,ABCC2,SEPTIN6,SLCO1A2,DNM2,SFT2D2,CACNG3,PPT1,RANBP6,TNF,VAPB,GRPEL2,ACTB,RPA2,ERLEC1,ING1,SEC13,TESPA1,TOPBP1,GOLPH3L,CDK5,BCL6,RAB11B,ARL4D,CTDSPL2,RANGRF,SEC22A,FGF7,SNX22,CHRDL1,HINFP,FITM1,PITPNA,SSR3,CDKN1A,MDFI,TMSB4X,TOMM20,RAB37,IK,NUP35,RB1,GPR89A,RAB31,TMEM107,EXOC3,YWHAB,RP2,GJA1,SEC61A1,H1-5,CASC3,ARF6,TP53,SPCS3,STARD5,STK4,MDM2,SDCBP,SSR1,EHD1,SSR2,NCBP2,SYNJ2BP,KIF3B,SLC15A1,HSPA8,SNX20,LARGE1,CRABP2,ZNHIT3,ANO3,TRAM1,ARHGAP1,CER1,DLG4,ARF4,NUP42,TMEM147,TMED7,TOR1B,RPAIN,HOMER1,APOC2,CDAN1,RAB3C,SAMM50,KPNA2,SLC51A,SNX2,SLC22A6,IPO8,HEXB,GPHN,FAF1,TNFAIP8L3,APOO,HOMER3,SUFU,CHMP5,FYTTD1,MAPRE1,CD3G,MLC1,SGTA,BET1,SCFD1,CHMP4C,SLC15A2,RBM15B,OSBP,NEDD8,ZFAND2A,LRWD1,LCA5,FBLN5,EMC4,JAGN1,HYCC1,RAB29,RABL3,NAPG,RAB1B,VAMP8,DHX9,TOMM22,RAB3B,CMTM6,GAS8,SRSF7,ZNHIT6,PPY,MCM8,TVP23B,ISG15,THOC3,SLMAP,PRPF19,OS9,CSE1L,COPZ2,SLC66A2,WDR11,RABL2B,VIPAS39,HGS,RAB28,JAKMIP1,SYNGR1,SOX9,CBL,BAG3,GHRL,VTA1,DLG3,RAB3A,CHST11,DLG1,RAB13,EMC1,FIS1,CBLN1,POLA2,NAPA,TOPORS,BECN1,ABCB9,UBAC2,DDX42,RAB4A,KCNB1,FCHSD2,ZDHHC15,CDC42,ARFIP1,RTRAF,FERMT2,GOSR2,CSNK1E,SCG2,RAB18,HNF1B,NXT1,RAB9A,ID1,YWHAH,STK3,C1QL2,ATP6V1D,UNC119B,STX8,MAVS,CPTP,AP2M1,RUVBL2,COG1,VTI1B,SLC25A17,SEPTIN7,HSPA5,IFT22,MDC1,TULP3,CD81,CCDC186,ODR4,XPO1,SCN3B,SLC2A1,UBAP1,SPTBN1,RAB33B,TIMM13,LACRT,STAR,NPC2,LAMP3,YKT6,NUP37,VMP1,ARFGEF1,RAB14,SCG5,DERL2,SYK,STX16,SELENOT,ZC3H11A,STX11,TMED9,STK11,TESC,LIN7B,SGF29,ZDHHC17,HDAC6,WBP2,CBLN4,TRAM1L1,EXOC2,EHD3,ARL6,ARL2BP,NUP62,IGF2BP1,NHERF1,TIMM8B,DRD1,PIH1D1,USE1,GLRB,PRPF31,RAB5A,STX6,SNAP23,VIP,NPTX1,RNF26,XRCC5,PICK1,VAMP3,VPS54,TRMT10B,YIPF5,NLGN1,NUP107,RAB22A,TIAM1,ARFGAP3,PAFAH1B1,CACNB2,ZFAND2B,PHAX,MAGOHB,GPIHBP1,NEO1,SURF4,STAU1,STX10,ROCK1,THOC1,WRAP53,OLFM2,CHTOP,LRP10,LAMTOR3,INSIG2,PARP11,HNRNPA2B1,PMP2,STX18,THY1,UTP25,ABCG2,HIKESHI,FABP5,EMC8,AP2S1,PRELID1,SEC62,PRRT1,SNX24,LAMTOR2,CTSA,YWHAZ,CPLX1,MIR301B,BSCL2,SRP72,NR0B1,AGK,PIK3R2,CCDC47,WDR19,MTX2,PIK3R1,RAN,BICD2,BET1L,GORASP2,FZD4,STX17,TCP1,TIMM21,NSG1,CALR,ABCB1,SNX18,ENY2,RFTN2,UCP2,NFKBIA,ROMO1,DKC1,KICS2,TXN,TNFAIP3,NUDCD3,RAB3D,IL1B,AKT1,AIFM1,ARFGAP1,PPP3CA,WNT7A,FKRP,TSPAN10,VPS39,TMED4,FUBP3,SLCO3A1,NRP1,PLA2G5,TSG101,PIP5K1A,TMEM88,PRKCE,SLC25A10,SYVN1,SLCO1B3,SLCO2B1,BUB3,CPE,TOLLIP,FHIP1B,TSPAN5,CYB5R4,XBP1,LMBRD1,SYNRG,LHFPL4,PAK2,TGFBR2,ZDHHC14,ARL11,DDX1,KPNA1,THOC6,GPM6B,GLTP,LRRTM1,DNAJC27,BBS5,ACVR1C,G3BP2,MACIR,IMMP2L,RAB23,CHMP1A,NOP58,DDX39B,CETN2,EFCAB7,AHCYL1,LAMP2,ID4,TOM1L1,HEXA,TRAF3IP2,BAX,RTP4,EIF4E,TMED1,ERRFI1,AKT2,VPS26B,FAM149B1,EMC10,CLIP3,SNAP29,LMNB1,MIA2,MIR130B,TXNIP,EDNRA,PEX5L,SAR1B,PAX6,SMYD3,XPOT,TP53INP2,SCAMP2,PIGW,CHMP2B,PNPLA8,OPTN,VPS18,MCL1,ZBTB16,FAM53C,ATG7,KCNIP3,FABP4,PPP1R10,TIMM17A,TNIK,EHD4,AQP11,DNAJB6,SFN,HM13 |
| 2.337e-15 | -33.69 | ATG13 (autophagy related 13) | protein interactions | 9776 | 207 | 112 | 19454 | 5460 |
NCOA5,NUFIP2,RPL27A,STAU1,PHB2,HNRNPA0,RPS28,XRCC5,DDX39B,DDX5,TRIM5,ATG3,YWHAZ,FAS,RPS26,RPS5,SFN,HNRNPC,RPL39,ATG101,RPL35,SNRNP40,MATR3,RPL19,RPL10,EIF3K,RPS9,RPL37A,SMNDC1,OTULIN,RPS23,RPL18,SNRPE,MTA2,RPS7,GABARAPL1,RPL29,EMC8,RPS4X,RPL28,PABPC1,HNRNPA2B1,RPL31,RPS24,RPL23,YWHAB,RB1CC1,RPL6,ATG9A,PSMD3,EIF3D,YWHAH,YWHAG,ATG7,RPL7,HNRNPL,RPL8,RPL9,HP1BP3,RPLP1,RPLP2,MAP1LC3A,RARS1,RPLP0,STAMBP,RPS14,ATG16L1,GABARAPL2,RPL4,RPS15,MARS1,GABARAP,EIF4E,RPL27,BICD2,EIF3G,RPL7A,C9orf72,ST13,RPL13A,NDN,OTOS,RPL22,RPS3,RPS20,RPS12,TRIM27,SESN2,TAB2,ILF2,RPSA,YTHDF2,RPL15,MAP1LC3B,HNRNPK,RPL17,RPS13,DHX9,RPL3,RPL23A,RPL24,BECN1,MUL1,RPL10A,RPS2,KARS1,RPS16,RPL35A,TMPO,RPL32,ALYREF,RPL12 |
| 2.451e-15 | -33.64 | RPL38 (ribosomal protein L38) | protein interactions | 6169 | 286 | 143 | 19454 | 5460 |
AGR2,DRG1,RPL23,AHSA1,POU5F1,CBL,RPL6,WWP2,DDRGK1,MAP3K14,HNRNPA1,RHOH,RPL7,RPS10,PHB1,FOLR1,RPL9,RPL8,RPLP2,RPLP1,NGB,RPL18,RPS23,SLC1A2,RPS11,RND3,B3GNT2,RPS7,RPL29,KRAS,EMC8,RPL28,RPS4X,RPL31,TMEM147,SRSF7,SLC2A8,RUVBL2,PSMD14,RPS5,RPS26,CUL2,GRB10,SFN,CUL3,MYC,BTF3,RPL35,RPL19,RPL10,MAD2L2,ESR2,PHF21A,RPS9,SEC61B,AP2M1,RPL37A,EMC9,PIH1D1,PAFAH1B1,RPL27A,EEF1G,STAU1,UFL1,G3BP2,ASB3,RPS28,MRPL34,RPL24,NME2,RPL10A,RPS2,ENY2,COPS5,HDAC6,PRNP,FZR1,RPS16,CAND1,RBM42,TFE3,RPL12,LDLR,DNAJC2,TFCP2,SRP72,HBP1,RPSA,NDUFA2,FBP1,UBL4A,RPL15,SRPRB,VRK1,RPL17,RPS13,PSEN1,MEPCE,EHD4,MAP1B,RPL23A,RPL3,RC3H2,SPOP,UBE2H,IGF2BP1,RPL7A,PPP1CC,RPL26,RPL10L,CHMP5,RPL13A,RPL22,VIRMA,BCCIP,SMURF1,METAP2,RPS3,MRPL53,PSPC1,CCNF,RPS12,RPS20,PTEN,ZCCHC17,RPA2,HAUS2,RPLP0,HEXIM1,RPS14,CDK7,CDC42,RPL4,FBXW7,KDM1A,HSPA5,PIAS1,SIRT7,BAP1,RPL27,RHOU,RPA3,RNF113A |
| 2.644e-15 | -33.57 | DHX36 (DEAH-box helicase 36) | protein interactions | 170506 | 281 | 141 | 19454 | 5460 |
MIR31,MIR221,MIR1-1,MIR143,IFI16,ACP6,CPEB1,MIR29C,HNRNPA1,MIR9-1,PAIP1,RPS10,DHX15,PHB1,MIR7-2,SRSF1,MIR141,HEBP1,MIR214,EZH2,MOB3C,E2F4,ZNF263,MIR222,NUP42,MIR155,KRAS,G3BP1,MRPS17,FGF3,RBM3,MIR9-2,RPL31,RPS24,SRSF7,MIR206,ZC3H7A,DCAF4,ATG3,ILK,RIT1,MIR363,HNRNPAB,CUL3,HNRNPC,MYC,ZNF668,MIR98,TAGLN2,ESR2,RPL19,APEX1,MIRLET7D,CMTR1,S100A6,MIRLET7B,LARP4B,PAK2,PRKAB1,RPL27A,PABPC5,STAU1,UFL1,MIR106A,NUP50,EP300,DDX5,SNRNP70,MIR34A,RPS2,MOV10,COPS5,MIRLET7G,CGAS,CAND1,RPS16,SURF6,TLR1,MIR429,KRR1,MIR106B,SYNCRIP,MIR25,PRR3,DISC1,MIR17,MIR20A,ILF2,RPSA,TP53,H2AJ,RPL15,APOBEC3D,MIR200C,MIR15A,RPL17,MIR16-2,PTGES3,RIGI,MEPCE,RPS13,MIRLET7C,MIR200A,DHX9,HINT1,SEPTIN7,RPL23A,IVNS1ABP,MIR145,RC3H2,UBE2H,MAPRE1,ZBTB38,CIAO1,RUNX1,CCNF,PSPC1,MIR16-1,RPS3,FGFBP1,METTL14,RPA2,MIR7-1,RPL26L1,HEXIM1,ZNF574,MIR21,MIR34B,RBMS2,MIR1-2,AGO1,MIR7-3,MIR29A,MIR107,SIRT7,MIR205,RPA3,MIR10B,RNF113A,MIR34C,MIRLET7I |
| 2.682e-15 | -33.55 | U2AF2 (U2 small nuclear RNA auxiliary factor 2) | protein interactions | 11338 | 623 | 265 | 19454 | 5460 |
CHTOP,FTSJ3,CCT2,THOC6,STAC3,HNRNPC,PSMA4,HNRNPAB,MYC,SNRPB,PSMD1,BTF3,PSMD6,SNRNP40,STAT1,TAGLN2,MATR3,PSMB6,CMTR1,VDAC2,SF3B4,PRMT5,NCOA5,LAP3,PHB2,STAU1,TRA2B,SRSF2,HNRNPA0,UFL1,SAP18,SNRPA,DDX39B,SLU7,DDX5,YAF2,EP300,SF3B1,HSPA8,AGR2,AK2,WWP2,RPL6,IFI16,DDRGK1,PPIB,SNRPA1,DYNC1I2,SNRPD3,SUMO2,HNRNPL,HSP90AB1,SRSF1,RBM5,FABP5,PSME2,EED,ZNF526,SMNDC1,TUBB4B,RPL18,ZRANB2,UBL5,EEF2,ISG15,TCF23,VDAC1,RUVBL1,PSMA1,KRAS,PSMA2,HNRNPF,POLDIP3,HNRNPDL,CCAR1,PABPC1,CCT8,PDIA6,EWSR1,RUVBL2,RC3H2,RRP7A,UBE2H,ATP1A1,SMARCA5,SUGP1,RPF2,ST13,CFL1,ADRM1,EIF4H,SRPK2,PSPC1,SF3B6,SGTA,RPA2,HECTD1,TFIP11,PPP1R8,CHIC2,CDC42,RBM22,HDAC3,HSPA5,TRIM3,BAP1,DDX46,LCP1,RNF113A,PGK1,H2AC4,CHCHD1,SNRNP70,MAP4,RPL10A,USP15,RBM17,TPM3,COPS5,FZR1,CAND1,CDC5L,TMPO,DKC1,ALYREF,SYNCRIP,MRPS9,HCLS1,RAC2,NHERF1,IK,DDX42,NUPR1,CERK,DUSP1,HNRNPK,PSMA5,SRSF12,PSME1,MAP1B,RUSF1,DHX9,YWHAZ,RIT1,HSP90AA1,CUL3,SAMHD1,ACTB,TUBB,PRDX2,SNRPB2,RAN,S100A6,SNRPD1,SNRPD2,RPL37A,PSMB7,MTX2,PSMC1,NKAPD1,PSMD10,DDX23,PDAP1,HNRNPD,PRPF19,PSMD3,PDIA3,PRDX1,TRA2A,HNRNPA1,SPTAN1,DPPA2,DHX15,PPIA,SRSF10,PSMB5,PSMB4,PHB1,FOLR1,ARL11,GDI2,RPN1,EZH2,SNRPE,JPT2,SF3B5,KHDC4,RAF1,ANP32A,PPP2R1A,TRIM37,DHX16,LASP1,RBBP7,FLOT1,SRSF4,PSMD12,UBE2A,HNRNPA2B1,SLC25A5,ZYX,HSPD1,SRSF7,SRSF8,RPS24,PCNA,MAPRE1,CASC3,SMAD2,NONO,AR,DNAJC8,USP14,TUFM,SMAD5,GNAI2,VIRMA,LURAP1,TUBA1B,EIF4A3,CCNF,MSN,GANAB,GSK3A,METTL14,HSP90B1,LMNA,ARHGAP1,RBFOX2,SAP30BP,SF3A1,HMGB1,FBXW7,DGCR8,SIRT7,PRPF4,DVL2,RPA3,ESYT1,CRBN,BRD3,DNAJC7,ERCC3,CALR,GRSF1,TOP1,PRNP,CWC15,MDM2,RCHY1,SMAD3,PSMB1,ILF2,H2AJ,THAP1,RPL15,MAP2K3,EEF1A1,THRAP3,HSPE1,HUWE1,CTNNBL1,HINT1,HAPSTR1,SEPTIN7 |
| 2.968e-15 | -33.45 | KAT6A (lysine acetyltransferase 6A) | protein interactions | 7994 | 504 | 223 | 19454 | 5460 |
LLPH,MRPL51,CCDC47,TIMM8A,RPL15,TRIM63,TTC4,RPS13,MRPL22,MRPS18C,NKRF,RPL23A,MPHOSPH10,SPATS2L,RPL35A,PRNP,TOP1,MRPS23,ZBTB2,H2AZ1,RPL12,SMAD3,EIF4E2,NUDT12,CDK1,ZNF574,NOL7,RPLP0,RPL26L1,HNRNPH3,RPS14,NPM3,NUCKS1,RPL4,DAD1,BRIX1,SQSTM1,ASCC1,PIP4K2C,STK38L,RPL26,RUNX1,RACGAP1,ZNF622,RPL13A,DEK,RPL22,VIRMA,PELP1,SCAMP2,EIF2AK2,PRKRA,RPS20,RPN1,EXOSC3,RPS11,SNRPE,NEU1,RPL29,MRPS17,PCGF6,SSRP1,MORC2,HSPD1,PPAN,HNRNPA2B1,JAK1,INO80C,MRPS11,RPS24,MRPL18,RSBN1L,RB1CC1,PRPF19,HMGA1,MRPS35,DPY30,RPL7,CGGBP1,ZNF593,RPL9,SP2,RPL8,MYEF2,MRTO4,RPLP2,HP1BP3,RPLP1,IDH3B,MRPL57,ZBTB39,CMAS,UPF3B,CCDC86,C1D,ZFP64,JADE1,YWHAZ,RPS5,LSM14B,NOP16,MRPL16,MRPL23,RPL7L1,MAD2L1,RPL19,FAU,CPSF1,RPS9,RBM34,ACOT13,MRPL33,TAB2,ZNHIT1,SNAP29,MRPL47,TP53,H3C1,HNRNPK,KPNA2,MNAT1,RPL17,RUSF1,RPL3,MRPS18B,DHX9,RPL24,RPS2,CDK12,NOL12,USP15,CENPP,RBM17,CSNK2A1,TMA16,PPIL4,RPS16,RPS27L,SHPRH,NKAP,SLAIN2,SYNCRIP,STT3A,ALYREF,RPL32,ZNF326,HEXIM1,LUC7L3,ING5,POLR1D,MRPL40,MRPL41,RPL27,PML,HNRNPH2,EXOSC4,MRPS16,EXOSC1,RBM7,AKT1,CCNB1,RPL7A,CEP70,MRPS21,RSL24D1,SRPK2,RPS3,UQCRC2,MRPS28,CSNK2B,SMARCB1,ZRANB2,RPL18,TAF10,TRMT1L,TOP3B,RPS7,KIF2A,CHCHD2,HMGN4,RPL28,RPS4X,RERE,RPL31,ABCF1,PABPC1,EWSR1,H2BC17,ARHGAP5,MGMT,YWHAB,DDX50,MRPL9,MEAF6,HNRNPL,AFTPH,NOB1,PNPLA8,MRPS18A,EIF4B,TRMT112,CSNK1A1,RPL27A,MRPL12,FXR2,STAU1,RPS28,MRPL34,DDX5,EP300,TFDP2,H1-10,FTSJ3,COP1,OST4,CREBBP,ZCCHC7,SNRNP40,CBX5,APEX1,RPL10,GTF2F1,MRPL13 |
| 2.979e-15 | -33.45 | MMGT1 (membrane magnesium transporter 1) | protein interactions | 93380 | 377 | 177 | 19454 | 5460 |
RALA,UQCRC2,LIG3,GNAO1,RC3H2,SLC25A1,SUB1,SLC35B4,LPAR1,PIP4P1,ABCC2,TMEM254,DLAT,DERL1,RAB9A,SSR1,CYC1,MPV17,CDC42,TMED9,DNAJC1,STX6,TMPO,COX4I1,RAP1B,POLB,ADGRE2,RBM17,PPIL4,GAPDH,SLC7A14,TMEM33,RAB3B,FKBP8,RUSF1,YIF1A,TFRC,SLC25A24,GNAI3,INSIG2,KIF1C,RAP1A,TAGLN2,ATP5F1B,ESR2,ATP6AP2,VDAC2,RRAS2,FIS1,MCAT,MDH1,ZMAT3,PSMD1,EMC1,PHB2,SAP18,SF3B1,LAP3,GOSR2,SEC62,TTC9C,TRIR,RBM5,GYS1,CORO1C,NDUFB8,SLC38A7,RAB5C,NDUFV2,FAM241A,CHCHD2,TMEM60,KRAS,VDAC1,CCAR1,TUBB4B,PDHA1,NDUFA12,SUPT5H,RANBP1,DNAJC25,TECR,GNAI2,SEC63,DEK,ENO1,GANAB,CHCHD6,RALB,TRAF3IP2,DNAJC8,MFSD3,MME,RTN4,LMNA,STOM,GRM2,SEC22B,UQCRC1,ST7,ANKRD46,EXTL2,CAV1,PTPN1,HSD17B11,TMEM42,KIAA1143,ESYT1,CALR,SLC25A46,EMC4,TMBIM6,GALNT2,STX8,TCOF1,SFXN1,EMC2,DMAP1,CCDC47,NDUFA2,LBR,THBD,TUBB,SPCS1,CHCHD3,CYB5R3,RMDN3,SEC61B,TMEM229B,SLC35E4,NDUFB7,TMED4,NOP53,PXMP2,PYGB,ATP2C1,EMC9,MFAP1,FKBP10,MYL6,MTX2,OTULINL,PRDX3,ERLIN1,EGLN3,TMEM237,DHX15,FOLR1,TMEM14A,PHB1,OCIAD2,MFSD5,XPO5,FXYD6,RHOG,VPS4A,STX1A,STOML2,EMC6,EMC8,S100A10,FLOT1,PLPP6,TMT1A,HNRNPA2B1,STIM1,RPN1,GDI2,NDUFS6,STX12,RPS11,CYB5B,ANP32A,EMC10,FAF2,GFPT1,ERLIN2 |
| 3.061e-15 | -33.42 | RPL27A (ribosomal protein L27a) | protein interactions | 6157 | 418 | 192 | 19454 | 5460 |
TRMT11,SMU1,GTF2F2,MRPL13,RPL10,BTF3,MYC,SFN,COP1,RPS26,ICAM1,FTSJ3,HSPA8,RAB5A,UFL1,STAU1,PAFAH1B1,PIH1D1,MRPS18A,EED,RPS10,EIF2S1,MRPL9,DDRGK1,RIOX2,RPL6,WWP2,DRG1,MAGOH,AGR2,RPL31,ABCF1,PABPC1,RPS4X,KRAS,ISG15,SOX2,RPS7,KIF2A,TOP3B,TRMT1L,RPL18,RPS23,ZNF526,PSPC1,RPS3,RPL10L,PRKACB,RPL7A,EXOSC1,IGF2BP1,UBE2H,SPOP,TRIM23,RC3H2,RNF113A,BAP1,RPL27,NLE1,MARS1,RPS15,WDR3,MRPL40,GABRA1,CFTR,DYRK2,HEXIM1,KLF4,ZNF770,ACACA,RPA2,MRPS9,RPL32,MALSU1,RBM42,FZR1,CAND1,RPS16,RPS27L,CD81,COPS5,CSNK2A1,ENY2,RPS2,RPL10A,SNRNP70,RPL24,RPL3,DHX9,MEPCE,RPL17,UBL4A,MRPL47,RPSA,TP53,TFCP2,DNAJC2,RPL37A,SEC61B,RPS9,FAU,RPL19,RANBP6,SIAH1,RPL35,RPF1,MRPL16,RIOK2,HNF1B,CUL2,CUL3,RPS5,RIT1,NOA1,BRCA1,G3BP2,GPC1,DUSP22,DET1,EMC9,RPLP2,RPLP1,RPL9,FOLR1,RPL8,PHB1,RPL7,CCAR2,HNRNPA1,MRPS35,RB1CC1,CDKN1B,RPL23,DICER1,MRPL18,TRIP4,HNRNPA2B1,G3BP1,RBBP7,B3GNT2,RPS11,EZH2,CHMP4C,PRKRA,RPS12,RPS20,PTEN,CCNF,EIF4A3,METAP2,RPL22,NDN,RPL13A,AR,PPP1CC,USP14,PRKCB,KIN,DVL2,RPA3,MRPL20,RPL4,HMGB1,FBXW7,RPS14,TPT1,UBA52,EEF1E1,RPLP0,RPL26L1,RPL12,RCHY1,CDK9,MRPL24,RPL35A,MRPL50,PRNP,HDAC6,TIAM1,RPL23A,MRPL22,RPS13,MRPS18C,HUWE1,VRK1,FNTB,RPL15,FBP1,MRPL11,MRPL51,SRP72,MRPL49 |
| 3.076e-15 | -33.42 | MOV10 (Mov10 RNA helicase) | protein interactions | 4343 | 1273 | 482 | 19454 | 5460 |
CREB3L4,MSRB3,MRPL49,APEH,ILF2,YTHDF2,MRPL11,EEF1A1,APH1A,BACH1,PRDX4,PDE2A,MRPL22,RPS13,ZNF787,NSDHL,SLC25A10,EXOC2,ARL2BP,EPOP,EMC4,ZBTB2,CAV1,POLE3,SLC25A17,DFFA,GRM2,LMNA,MRPS34,ZNF574,SAP30BP,ATG16L1,PSMC4,RBMS2,EDF1,COMMD3,DESI1,DGCR8,POLDIP2,SIRT7,SLC39A9,SQSTM1,ZNHIT3,TDP1,CDC16,CREB3,ATP5F1A,SLC25A4,RILPL2,VKORC1L1,STUB1,INPP5K,DTYMK,PRKRA,EZH2,GTPBP1,CYB5B,ACO1,KHDC4,EMC10,E2F4,FEN1,WDR37,GTF2E2,CBX7,G3BP1,EMC8,UNC119B,PPAN,VPS26B,RPS24,ATP6V0B,ZC3H7A,ADAT1,NQO1,TMEM164,PRPF19,PSMD3,HEBP2,UBXN6,TRA2A,MAP3K14,SNX1,KIF3B,RPLP1,XPO5,TSG101,AGGF1,MTX2,LMO4,IDH3B,MCMBP,G3BP2,MCRIP2,RNF10,MYO6,TAFAZZIN,TBC1D16,CUL2,CUL3,USP13,DSN1,MCM4,PDE4B,RPL35,UMPS,GNB1,CHP1,CYB5R3,APOBEC3G,CPSF1,PSMC3,GCHFR,MTCH2,MSRB1,UBL4A,ZMYM4,ZMYM3,WBP11,URM1,HADH,ACTR1A,MECR,TOMM40L,CDC40,BACE1,PCYOX1L,DDR1,EIF1AD,IDH1,MRPS18B,SNRNP70,TPGS2,LANCL2,TMEM11,AGPAT1,RPL10A,RPS2,COPS5,SSBP4,NR2F6,TWSG1,IFRD2,SURF6,FUNDC2,DKC1,EEF1B2,SYNCRIP,COQ8A,ZNF326,SAMM50,SPRYD4,GALNT1,RPA2,ACACA,PRKCA,GIT2,HEXIM1,ING5,CREBZF,FGF13,CFTR,HSPA5,TOMM20,APMAP,RNF113A,HNRNPH2,RC3H2,PKNOX1,ELAVL2,CEP85,RPL10L,MRPS21,SRPK2,LIG3,RPS3,SMNDC1,GLE1,CRKL,SUPT5H,STBD1,TOP3B,OAZ2,PAIP2B,TNPO2,CCDC134,VDAC1,NUP42,H1-6,POLDIP3,RBM3,PABPC1,DNAJB4,GIPC3,CIAO3,GSTM3,PPFIBP1,PPIB,PAIP1,ADCK1,HMG20A,LRRC61,SRSF1,MPDU1,CLK4,SPINT2,RFX5,SIGMAR1,NCOA5,FAM89B,PABPC5,STAU1,HNRNPA0,HIRA,PYM1,PTRHD1,AKAP1,RAP2A,EP300,RAB5A,CHTOP,COMMD9,TSEN54,ZNF343,PCCB,MLF2,SNRNP40,TRIM29,CAVIN2,VCF1,DES,PPP5C,MORC4,SPSB3,NDUFS3,HINFP,CMPK1,EXOSC8,APOBEC3D,CD2BP2,PTGES3,APBB3,CDC42SE1,MRPS18C,GARRE1,NKRF,TSPAN17,ERG28,ANKRD49,SLC35B3,NPR2,SMDT1,GRSF1,GOLPH3L,PLEKHF2,MRPS23,KRR1,HRAS,HDHD3,RPL12,TES,DLGAP4,PRR3,CHMP1A,UBAP1,HNRNPH3,PIP5K1A,DDAH1,JMJD8,ADIPOR1,SF3A1,UQCRC1,PIK3R2,MIEN1,FBXW7,NF2,GID8,RPA3,PRIM2,HERC4,PAIP2,RPL26,PNP,WDR83OS,EIF2AK2,CCNF,GNPDA1,NTN4,NDUFS6,CHMP4C,RPS11,STX12,B3GNT2,RAF1,DPH5,RBM12,IFNGR1,GABARAPL1,GUK1,AHCYL1,COPS4,CIPC,HSPD1,SRSF7,MRPL18,DICER1,RB1CC1,VCPIP1,MRPS26,HAX1,HNRNPD,BABAM1,MTRF1,RAB32,ZNF207,HNRNPA1,DHX15,PSMB5,RPL9,KLHL7,RPLP2,SNX17,LARP4B,ANXA7,SLC25A3,ELOVL1,ASB8,NDE1,ACTL6A,SUPT4H1,NUDT3,RFXANK,YTHDF1,TMED3,NOP53,SRM,FBXO30,EXD2,YWHAZ,DCAF4,BRCA1,PSKH1,FYTTD1,LSM14B,ILK,CCDC25,RPS5,SCFD1,PKP4,LIN7B,TMED4,NFYA,SMARCE1,TAB1,LAMTOR3,B4GALT4,PRRC2A,MAD2L2,USP5,ZNF174,POLR3B,SURF4,DDX42,KIF1C,TP53,RPIA,H3C1,MEPCE,MAP1B,DHX9,SHC1,CHCHD1,MED29,AKAP8L,USP2,ELOC,TPM3,EDC3,E4F1,FZR1,TMED9,CAND1,STX6,ITGA6,XXYLT1,GATAD1,RAP1B,LUC7L3,KLF4,CYC1,SEPHS2,TFIP11,DYRK2,MPV17,AGO1,STK38,NME4,WDR55,GRPEL1,RPL27,BAP1,GID4,SMG5,LSM12,ENDOD1,UBE2H,IGF2BP1,ATF4,RPL7A,CFL2,EIF4H,DYRK1A,CLCN6,CDC20,SLC25A39,TBCCD1,PITPNB,RNF187,SEC61A1,LSM10,HGS,DHX38,SPG21,TMBIM1,ANAPC13,XPNPEP1,SLC20A2,NAB1,LSM14A,RPL31,FAM168A,H2BC17,SELENOW,WWP2,RPL6,RAB5C,IFI16,DDRGK1,CTNNB1,CPEB1,SNRPA1,RNF144B,AASDHPPT,SUMO3,RPS10,ZNF740,CCT7,FUBP3,RBM5,RPRD1A,CNDP2,MED31,ATP6V1C1,SYK,SLC31A1,UFL1,NDUFS2,ABCC5,HERC3,PEBP1,TAPBP,S100A11,FBXW11,MRPS25,CIRBP,CKB,H1-1,RCL1,ATP5MC3,RPS26,HNRNPC,HNRNPAB,MYC,UFD1,PSMD1,TAGLN2,MATR3,ESR2,RPL10,CMTR1,MRPL13,RETREG3 |
| 3.145e-15 | -33.39 | G3BP2 (G3BP stress granule assembly factor 2) | protein interactions | 9908 | 493 | 219 | 19454 | 5460 |
MIR205,PNO1,MTDH,SQSTM1,MIRLET7I,RPL4,MIR7-3,NF2,ATG16L1,RPS14,EIF3J,EDF1,METTL14,RARS1,RPL26L1,RPLP0,CCNF,MIR16-1,PTEN,RPS20,RPS12,RTRAF,RPL13A,RPL22,TECR,USP14,IVNS1ABP,MIR145,STK24,PPP1R12A,HSD17B10,RPL23A,EIF3E,RPS13,YTHDF2,RPL15,PSMB9,MIR200C,MIR17,SRP72,MIR106B,RPL12,SRP14,MIR25,MDM2,CDK9,MOV10,GRSF1,NFKB1,HDAC6,MIR34A,YTHDF1,MIR106A,COIL,WDR77,LARP4B,ATP5PO,SLC25A3,EIF3K,FAU,SEC61B,RPS9,TENT5C,RPL35,RPL7L1,PRRC2A,MIRLET7D,CUL3,GRB10,MIR98,PDE4B,MIR363,RPS5,TRIP4,RPS24,FAM76B,ZC3H7A,LASP1,TNF,G3BP1,RAF1,RPL29,NUP153,EXOSC3,RPN1,RPS11,MIR7-2,PHB1,RPL8,RPL9,RPLP1,HP1BP3,RPLP2,MIR141,RPL7,PIK3R1,HNRNPA1,SKIC8,RPL23,HNRNPD,MIR1-1,RPL27,MIR10B,BAP1,RNF113A,LSM12,RPS15,MARS1,MIR107,ZC3H15,MIR34B,MIR7-1,DYRK2,MIR21,RPS3,PHAX,EIF2S2,SRP54,PPP1R10,RPL7A,RPF2,RPS17,MTPN,RC3H2,SPOP,EIF3G,RRP7A,PDCD4,IGF2BP1,ATP1A1,SLC25A11,SNIP1,MIR200A,DHX9,RPL3,ABCE1,RPL17,MIR16-2,MEPCE,MIRLET7C,TP53,RPSA,ATP5PB,RPL32,COQ8A,SYNCRIP,MIRLET7G,RPS27L,CAND1,RPS16,FZR1,MIR429,COPS5,RPL24,SNRNP70,RPL10A,RPS2,RPS28,RFC4,EP300,HSPA8,STAU1,UFL1,TRA2B,FXR2,RPL27A,NUP62,NEK7,PPT1,EIF4B,NUFIP2,NFKBIA,CMTR1,VDAC2,PRMT5,MIRLET7B,SNRNP40,RPL10,SFN,MYC,BTF3,H1-10,RPS26,LSM14A,TOP2B,PABPC1,RPL31,MIR206,MIR155,KRAS,RPS4X,RPL28,TRMT1L,TOP3B,RPS7,MIR222,SOX2,RPS23,MOB3C,HGS,RPL18,FUBP3,DUSP6,MIR214,LYAR,NOB1,EIF2S1,HNRNPL,RPS10,UQCRH,WWP2,RPL6,IFI16,DDRGK1,MIR29C,MIR31,MIR140,DRG1,MIR221 |
| 3.339e-15 | -33.33 | STX12 (syntaxin 12) | protein interactions | 23673 | 243 | 126 | 19454 | 5460 |
VAMP7,TLCD4,RAB11B,RAB1B,RHOH,GJA1,NRSN1,SLC66A2,STX5,ATP6V1A,RAB35,MYEF2,PDZK1IP1,STX1A,AHSA1,FKBP4,LAMP2,ATG9A,LRRC4,RAB5C,LEPROTL1,VAMP8,KRAS,VDAC1,EWSR1,RPAP3,CCR1,ENPP4,TMEM14B,HGS,VAMP2,BZW2,RAB4A,MFSD6,ATP6AP2,LMBR1L,VDAC2,LAMTOR1,RHOB,FCER1G,KDSR,TM9SF4,RAB11A,CUL3,STX7,GOSR1,HSCB,RER1,NMRAL1,HSPA8,PMAIP1,RAB5A,TMEM106B,TBC1D17,EHD1,FAM234A,BET1,GOSR2,STX6,CAV1,ARF6,VTI1B,EIF2B2,SNAP25,EIF2B5,PRNP,RAP1B,RAC2,LMBRD1,HRAS,LAMP3,DPP4,MOV10,ATP5MG,LAMTOR2,RIGI,PTGES3,NSG1,NOC4L,RAB3B,STX18,SNAP23,MAP1B,STX8,RAB1A,TFRC,TMEM31,MAP1LC3B,TBK1,SNAP29,HOMER1,ACP2,RAB14,RHOJ,STX10,OPTN,CCNF,VAMP3,SCAMP2,NAPA,STXBP6,CISD1,RIC3,DNAJC5,RAB2A,VAMP5,VPS28,SLC7A1,NAPG,YKT6,TMEM167B,RAB9A,RHOU,TMX2,RPA3,ZKSCAN1,PTP4A2,LMNA,RPA2,EIF2B3,FGFR1,USE1,CDC42,ATG16L1,TIMMDC1,SEC22B |
| 3.461e-15 | -33.30 | SNRPA (small nuclear ribonucleoprotein polypeptide A) | protein interactions | 6626 | 471 | 211 | 19454 | 5460 |
ACAA2,NCOA5,ZC3H14,NDUFAF3,UFL1,HNRNPA0,SRSF2,TRA2B,STAU1,SAP18,DDX39B,SLU7,SNRPA,SF3B1,HSPA8,EP300,DDX5,CIRBP,CHTOP,THOC6,MYC,HNRNPAB,SFN,PAPOLA,HNRNPC,SNRPB,CPSF2,MATR3,SNRNP40,POLR2B,ESR2,SF3B4,SMU1,GTF2F1,SMNDC1,CAAP1,TOP3B,SUPT5H,NUP42,CCAR1,POLDIP3,HNRNPDL,CMTR2,PABPC1,RBM3,EWSR1,CRTAP,MAGOH,XPO1,DDRGK1,HNRNPL,TRIR,LYAR,SNRPA1,SNRPD3,PEG10,SRSF1,POLR2L,WDR82,EED,RPA2,SDCBP,RPRD1B,ZNF326,HEXIM1,TFIP11,ACACA,LUC7L3,DDIT4L,PPP1R8,CFTR,RBM22,CISD1,GEMIN8,RC3H2,LSM6,IGF2BP1,UBE2H,RBM7,SUGP1,CFL1,DAPK1,SMURF1,PPP1R10,SRPK2,SF3B6,DDX42,IK,NUPR1,CDC40,H3C1,HNRNPK,SNIP1,MAP1B,DHX9,SNRNP70,H2AC4,COPS5,API5,CAND1,FZR1,NKAP,RBM42,CDC5L,MRPS9,SYNCRIP,EEF1B2,ALYREF,APOBEC3C,USP39,MFAP1,TIMM13,PRDX3,SUPT4H1,YTHDF1,FYTTD1,CUL3,CUL2,RIOK2,PRPF31,ERH,SNRPB2,CPSF1,RSRC1,SNRPD2,SNRPD1,ZMAT2,EZH2,CHMP4C,SCAND1,NGB,POLR2C,SF3B5,POLR2D,SART3,SNRPE,TPD52,E2F4,PPWD1,SRSF4,SSRP1,CPLX1,AHCYL1,HNRNPA2B1,SRSF8,SKIC8,DDX23,HNRNPD,TST,RPL23,PRPF19,HNRNPA1,TRA2A,ZNF207,BUD31,SRSF10,DHX15,FOLR1,PHB1,IFIT2,TOX4,GRM2,LSM2,HNRNPH3,SF3A1,RBFOX2,TXNL4A,SNRPN,CDK7,RPA3,PRPF4,KIN,MYT1L,CDC73,PPIG,FBXO7,PPP1CC,NONO,MAGOHB,VIRMA,SMAD5,CCNF,EIF4A3,TRIM27,TRIM24,PTEN,TNFAIP8L1,GABPB1,POLR2G,ILF2,OTX2,DDX39A,EEF1A1,CD2BP2,EXOSC8,CTNNBL1,LSM4,HUWE1,THRAP3,SMN1,SNRPG,PQBP1,ZC3H11A,TOP1,THOC1,POLR2I,PRNP,NCBP2,CWC15,MRPS23,PRR3 |
| 3.731e-15 | -33.22 | HSPB1 (heat shock protein family B (small) member 1) | protein interactions | 3315 | 691 | 288 | 19454 | 5460 |
EIF4A2,GARIN2,CHCHD3,BAD,PELO,YWHAZ,BRCA1,SP1,PFDN2,HSP90AA1,ARMT1,ILK,CDC123,GRB10,CUL3,TOMM40,JPT1,PSMC1,TGFB1I1,CSRP1,IGSF21,SAT1,TXNL1,HADHA,PSMA3,JADE1,CRYAB,MFAP1,SLC25A3,MAPKAPK5,EHD1,ATXN10,HYPK,ERLIN1,SRSF10,DHX15,FOLR1,PHB1,IGBP1,CETN3,CDK5RAP3,HNRNPD,HAX1,MPHOSPH6,BCL2L1,PRPF19,PDIA3,HNRNPA1,HSPB8,TNF,G3BP1,LASP1,TRIM37,MCM6,SLC25A5,ZYX,HSPD1,HNRNPA2B1,CCDC32,ERP29,BAG2,EZH2,GDI2,NGB,NME1,RBPJ,EIF1AX,JPT2,B3GNT2,RAF1,GFPT1,ACTN4,ERLIN2,ZBTB17,ARMC6,YES1,SH3BGRL,VIRMA,STUB1,INPP5K,CCNF,OPTN,POP7,TUBA1B,ACAT1,ALB,MSN,UBE2I,TRIM24,CCHCR1,XPOT,CDC73,NAPA,NCKIPSD,CSK,SEC13,ATP5F1A,AR,GMPS,USP14,MME,RPA3,PRKCB,SQSTM1,TOX4,JUP,CDK1,CARHSP1,HNRNPH3,RARS1,PITPNA,SHOC2,WDR83,ACBD6,TPT1,MYL12B,FTH1,SLC7A9,CGAS,PRNP,CDK9,TOMM70,G6PD,MRPS23,CAV1,SLC25A12,PTPN1,AIFM1,DFFA,EEF1AKMT3,TES,FGR,CALR,HDAC6,GLO1,HUWE1,SERTAD1,TRIM63,PSEN1,OLA1,MSH6,PTGES3,SMN1,PC,UAP1,DMAP1,CAMK1,SRP72,MAP2K3,MAP1LC3B,EEF1A1,LBR,MATR3,STAT2,TIMM21,LRIF1,USP38,ACAP2,DES,LMBR1L,PHF12,DLST,NFKBIA,PSMD14,MYC,CREBBP,PSMD1,BTF3,UFD1,BAG3,TBC1D1,MLF2,FXR2,OXCT1,PHB2,PEBP1,DDX39B,XRCC5,HSPA8,RAB5A,ADSS2,MAP2K1,PPT1,EIF4B,PIH1D1,MED31,CAV2,ELK4,EDEM3,PCSK9,ISG20L2,EIF2S1,SUMO2,ELK1,HSP90AB1,DUSP6,GSTO1,IKBKB,FKBP4,CBL,YWHAB,HSPB1,WWP2,XPO1,YWHAH,CTNNB1,KRAS,HNRNPF,RUVBL1,HNRNPDL,UQCC2,PABPC1,RUVBL2,RPAP3,PDHA1,SUPT5H,ISG15,SOX2,EEF2,TRIM54,RALA,PRKCE,MYG1,SUCLG2,UQCRC2,PSMA6,PITPNB,GLOD4,TRIM23,RC3H2,ABCG2,UBE2H,CRYBB2,SLC25A1,AKT1,PSMB2,KDM1A,MRPL40,BVES,GRPEL1,HSPA5,CLU,UGDH,MAPKAPK3,PML,HSPB2,HNRNPH2,PRDX6,RNF113A,RPA2,PTPN22,WWP1,PRKCA,E2F6,CYC1,HECTD1,SPTBN1,HSPB6,CDC42,CFTR,PLG,FZR1,KCTD3,MYL12A,CDC5L,EEF1B2,STT3A,UBE2N,GNPAT,SHC1,LSM3,AKAP8L,MAP4,COPS5,CSNK2A1,TPM3,GAPDH,SEPHS1,MAP1B,TFRC,RNF8,KBTBD4,UBL4A,RPSA,MTCH2,TP53,DUSP1,ZMYM4 |
| 4.003e-15 | -33.15 | SFXN1 (sideroflexin 1) | protein interactions | 94081 | 397 | 184 | 19454 | 5460 |
CYB5R3,STARD7,ACTB,CHCHD3,PARL,SCN3B,PYCR1,ARHGAP19,FCER1G,LMNB1,RHOB,EXD2,ATP5MK,CMC4,NMRAL1,PMAIP1,HADHA,COIL,MTX2,PGRMC1,RND2,TIMM13,PRDX3,TIMM29,ATP5PO,NDUFA5,SLC25A3,PHB1,OCIAD2,MYEF2,AGK,NDUFS8,TLCD4,WIF1,STOML2,HAX1,HSPD1,NDUFA4,ZC3H7A,G3BP1,ETFA,CYB5R1,TOMM7,EZH2,NDUFS6,TMEM14B,OPTN,CCNF,SFXN2,CHCHD6,ACAT1,TXN,MMD,RHOJ,SH3BGRL,UQCRQ,VIRMA,NDUFB10,PYCR2,ATP5F1A,FBXO7,DEPDC1B,RPA3,TMEM126B,MAVS,UQCC3,PIAS1,ATG16L1,TIMMDC1,UQCRC1,CDK7,TIMM23,COX6C,STOM,GHITM,TIMM8B,AIFM1,LDLR,CDCA3,ARF6,CDK9,TOMM70,SLC25A12,ZBTB2,CIDEB,ATP5MG,ESYT1,RAB1A,SFXN1,HSD17B10,EMC2,ARF4,TMEM126A,TIMM8A,NDUFS3,SLC25A20,ILF2,TACO1,LMBR1L,DLST,GLRX2,ATP5F1B,APLNR,ESR2,COX6B1,MYC,COX11,KIAA1191,COX16,LAMTOR1,ICAM1,HSPA8,COX17,HDAC5,EP300,AKAP1,NDUFS2,EMC1,STAU1,PHB2,HIGD2A,DDI1,TOMM22,CAV2,HNRNPL,RHOH,UQCRH,NDUFV2,XPO1,AK2,AGR2,UQCC6,NDUFB5,EWSR1,USP30,VDAC1,ETFB,NCSTN,PDHA1,FAM136A,ACOX1,UQCRC2,EIF2S2,PTPMT1,CABCOCO1,NAA50,SLC25A1,ATP1B3,CHCHD4,ATP1A1,UBE2H,CALU,TMX2,DLAT,TDRP,GRPEL1,TOMM20,BCL6,GTF2H4,CDC42,CFTR,RPA2,SAMM50,SSR1,CYC1,CD274,COX4I1,FZR1,KARS1,COX5A,SMIM12,ATP5PF,CLPB,AKAP12,PSMB10,FKBP8,SNAP29,ATP5PB,FAM162A,APOO,GPD2,SURF4,COX19,SLC25A24 |
| 4.157e-15 | -33.11 | RBM42 (RNA binding motif protein 42) | protein interactions | 79171 | 327 | 158 | 19454 | 5460 |
DHX9,ABCE1,ZC3H11A,RPL23A,RPL3,NKRF,SNIP1,RIGI,EIF3E,SNRPG,RPL17,RPS13,THRAP3,HNRNPK,MRPS33,LSM4,CAMK2G,CD2BP2,RPSA,ILF2,ALYREF,KRR1,SYNCRIP,SRPRA,METAP1,RPL12,MRPS9,MRPS23,CDC5L,NCBP2,MALSU1,RPS27L,FZR1,RPS16,CAND1,COPS5,RPL10A,RPS2,RPL24,SNRNP70,CENPL,SLC35B3,PPIH,MTDH,PRPF4,RPL27,BRIX1,ZC3H15,EIF4E,NUCKS1,RBM22,RPL4,RPS15,EIF3J,SNRNP27,SNRPN,TXNL4A,RBFOX2,RPS14,RPLP0,LSM2,ZNF326,RPS12,RPS20,EIF2S2,SEC61A1,RPS3,RPL22,RPL13A,MRPS21,ZNF622,RPS17,RPL7A,UBE2H,PDCD4,IGF2BP1,LSM6,EIF3G,FHL3,RPS24,CCDC32,PABPC1,HNRNPA2B1,RPL31,HNRNPDL,MRPS17,RPL28,RPS4X,RPS7,TRMT1L,RAF1,SNRPE,RPL18,RPS23,RPS11,SEC61G,SMNDC1,RPLP2,RPLP1,RPL9,RPL8,RAB11B,SNRPD3,LYAR,LSM5,RPL7,HNRNPL,RPS10,EIF2S1,NOB1,DDRGK1,HNRNPA1,MRPS35,RPL6,PRPF19,DRG1,MRPS26,DDX23,PSMA3,RAMAC,DDX5,RPS28,SNRPA,NGRN,MRPS7,TNFSF10,SAP18,SSR3,STAU1,FXR2,HNRNPA0,UFL1,RPL27A,NUFIP2,MFAP1,EIF4B,LARP4B,USP39,CHAC2,RPS9,SNRPD1,RPL37A,SNRPD2,EIF3K,ERH,RPL10,PRRC2A,ESR2,SNRNP40,RPL35,EIF4A2,SNRPB,RPS29,PRPF31,NOP16,MYC,RPS5,RPS26 |
| 4.311e-15 | -33.08 | RHOA (ras homolog family member A) | protein interactions | 387 | 1186 | 453 | 19454 | 5460 |
RAB9A,PRDX6,SDCBP,RPA2,USE1,IDH2,PRKCA,ELMOD1,SPTBN1,CFTR,RALA,SMURF1,ROCK1,MOB4,QSER1,STX10,RAP2C,DNAJC10,ATP1A1,C9orf72,PTPN11,CHPF,TMEM33,SRPRB,SLC6A8,FKBP8,PALM2AKAP2,SLC25A11,SLC16A1,STX18,ABCE1,TFRC,BMPR2,UGCG,SNAP29,PREB,MTCH2,UBIAD1,ARL6IP5,DNAJC1,TMPO,STT3A,COX4I1,CAMLG,AGPAT1,EMC1,RER1,SSR3,GNB4,HSPA8,AKAP1,PAK2,SDC2,UBAC2,RASL10A,TMEM184B,FDFT1,GOSR2,ATP6AP2,NFKBIA,FAM83B,SPCS3,LAMTOR1,OSGEP,SLC38A1,MLF2,KRAS,NUP42,TMEM87A,RINT1,TOP2B,EFNB1,SEC11A,AAMP,RPL18,TOP3B,STBD1,FASLG,SOX2,RHOH,VAMP7,UQCRH,HSPB1,PPFIBP1,TBC1D5,CERS2,B2M,TMEM209,LRRC8D,OPHN1,MTDH,ITGA2,MAVS,JUP,GHITM,ATG16L1,SNRPN,HACD2,CNP,RAB14,RPL13A,YES1,SLC25A4,TECR,SH3BP4,SEC63,VAMP3,OPTN,STUB1,SMAP2,EIF4A3,GANAB,PTEN,EPHA2,NAPA,DEPDC1B,PPP1CC,HSPE1,CTNND1,SNRPG,LTBR,SLC25A10,STX8,NSDHL,DLG1,TTPAL,HAPSTR1,SNAP23,EMC2,HSD17B10,ZDHHC8,KRIT1,CCDC47,LBR,MAP1LC3B,SLC29A1,AGPAT5,PRNP,SLC25A17,SLC25A12,CAV1,SRPRA,HACD3,EHBP1,C2CD2,CDCA3,SLC2A1,MPHOSPH10,ESYT1,TIAM1,RELL1,TMEM199,EMC4,RAB23,ATAD1,NSFL1C,CXCR4,LUM,RTKN,HTR1A,PPY,PMAIP1,NUBP2,VAV2,NDUFA5,PRKAB1,RND2,RPE,ETF1,CHCHD3,CHP1,PIGK,FZD6,BLVRA,FAS,LMNB1,MYO6,VEZT,CUL3,TOMM40,EMC8,ETFA,RETREG1,JAK1,SLC39A7,VAMP2,STIM1,CTSA,CYB5B,MARCKSL1,TPD52,EMC10,LGR4,SNX1,SPTAN1,NDUFS8,ERLIN1,RAB11B,DNM2,WDR6,PHB1,GJA1,SGMS1,CYB5A,RHOG,PSMD10,CDKN1B,TAF7,RAP2B,TRA2A,WDR11,FTSJ1,CLDND1,GRAMD2B,MAIP1,TEX264,BAP1,TMEM185B,LRP10,DERL1,TNFAIP1,ARFIP1,SSR1,HBB,TFB1M,LEMD3,CSNK1G3,CYC1,MPV17,CDC42,UQCRC2,NECTIN2,TRAF7,PTPMT1,MACROH2A1,CISD1,ATP1B3,SLC25A1,RAB2A,ARHGAP21,GORASP2,AKAP12,CSE1L,RDH11,CLPB,YIF1A,CCM2,STRBP,CENPM,VTI1B,LMAN1,SLC38A2,STX6,MBD5,ACSL4,ITGA6,UBE2G2,FLRT2,RAP1B,SLC39A10,RAC2,VASH1,SLITRK5,KPNA1,NUS1,COX5A,NDUFS2,GOSR1,UFL1,TRA2B,ITGAV,PACSIN3,ABCC5,BMPR1A,MIA2,MAP2K1,USP6NL,BET1,IL6ST,TAMM41,ALG5,NCKAP1,MTG1,DLST,RRAS2,SLCO3A1,CRMP1,PSMD1,SLC30A5,STX16,SLC20A2,XPNPEP1,ROCK2,MX2,RAB18,GNA11,CDK5,TUBB4B,PTRH2,PDHA1,CCR1,ETFB,RAB1B,KCNA2,RAB35,FUBP3,STX5,ARHGAP5,DDX1,DDX50,RAB5C,WWP2,PTDSS1,YWHAG,OLR1,TENM3,CTNNB1,DDRGK1,YKT6,PDHB,SLC7A1,PIK3R2,CDC42EP4,BRIX1,RPA3,SOD1,PPM1G,DVL2,RHOU,SPCS2,RTN4,CTDSP1,GOLGA5,STOM,SLC12A2,SH3GLB2,MEST,AGAP1,RABL3,SEC22B,ARHGAP1,ADIPOR1,ST7,RHOJ,FERMT2,GNAI2,VIRMA,GAB1,CTNNA1,TUBA1B,SLC11A2,MSN,RPS12,ARFGAP3,SMAD2,NRP1,CNTNAP1,CSGALNACT2,HMOX2,AGAP2,FASTKD5,RIGI,RAB1A,PPP1R12A,SFXN1,NDUFS3,ITGB8,PDE6D,DHRS7B,TMEM126A,CMPK1,MTARC2,DCUN1D1,DERL2,MRPL50,MDM2,PTPN1,ACTA2,POR,TRPC1,OSBPL8,GRSF1,LAMTOR2,ATP5MG,HM13,DAG1,CYFIP2,PAFAH1B2,STX7,ATP2C1,EXD2,RABAC1,BIRC2,VAPB,ARMCX3,SLC25A3,GJC1,NOTCH2,DAAM1,PGRMC1,TOR1AIP2,PRDX2,LRRC8A,TUBB,REEP4,LAMTOR3,SPCS1,UBE2V2,GPR89A,ARHGAP19,RHOB,SLC7A11,SCFD1,CNIH4,ILK,VMP1,TM4SF20,NIBAN2,PIK3R3,PKP4,MRPL16,RPS27A,FLOT1,AHCYL1,SCYL2,SLC25A5,SCD5,CTNNA2,RPN1,NDUFS6,PCDH17,POLR2C,STX12,IFT22,MACO1,HSDL2,DLG3,FAF2,ERLIN2,IFNGR1,DIRAS3,SLMAP,PPIA,EGLN3,TMEM237,NUP35,SPRED2,MRTO4,CDK5RAP3,DNAL1,RAB32,ATG9A,PIK3R1 |
| 4.465e-15 | -33.04 | regulation of transport | biological process | GO:0051049 | 1621 | 617 | 18204 | 5365 |
ACTB,TNF,ADIPOQ,CACNB3,CX3CL1,MUL1,XCL1,PPT1,NDUFAF2,FCGR2A,AVPR1B,SLC25A4,MIR145,ATP1A1,VAMP7,LRRTM2,H1-1,RAB11A,ERLEC1,HMGB1,MIR495,ZDHHC8,MBL2,RANGRF,HFE,CTDSPL2,VPS28,RAB11B,CXCL12,GOLPH3L,RGS2,CDK5,STX1A,TRIM46,HECW1,S100A10,CXCR4,CAB39,OAZ2,PYCARD,STXBP6,PKIA,VAMP2,CXCL10,ATAD1,JPH4,TMSB4X,SPHK2,LRAT,ATG3,ASIC2,RAB31,MIR424,WDR44,SLC25A5,NPY5R,GJA1,CFTR,MIR17,SCN2B,AZIN2,TBC1D5,CNTN1,CLDN3,ARF6,CCR2,EDEM2,F2,SLC25A27,UFM1,PLSCR1,CAPN1,MIR133B,SDCBP,MDM2,LPAR1,SDC4,ARF1,TMEM30A,RCVRN,HPCA,SCN1B,MIR1-1,CLEC7A,SYNJ2BP,MIR34A,NCBP2,LEPR,VPS4A,EHD1,IL13,OAZ1,ARHGAP1,ITGAV,GABBR1,P2RY1,PLPP4,FGFR1,RAC2,TMEM38B,ADORA1,ADORA3,SGIP1,PTPN1,HSPA8,SCAMP5,ICA1,TMEM14A,HOMER1,NETO1,PTPN11,CRBN,LRRC8A,TRIM27,DLG4,APLNR,TLR4,RNF139,LGALS3,C1QTNF1,SLC6A4,EPO,CHCHD4,APOC2,B2M,CHRNB2,OSBPL8,MLC1,TSPO,JUP,SUFU,HOMER3,SLC16A1,SV2B,MIR212,SCFD1,PPARG,SFRP4,SVIP,RIMS4,FCN2,TGFB2,CHP1,IL1A,MIR192,OSBP,MIR144,PPFIA2,FGF10,RAB29,TF,KCNMB1,MIR9-1,JAGN1,IL2RG,GCLC,RAB3B,MIR30D,WASL,DKK1,DHX9,GSTM2,VAMP8,SPP1,VPS4B,CDH13,SNX33,REEP6,ADTRP,GREM1,ADRB2,CHRM1,MIR200C,OR51E2,ATP2B4,CD151,FKBP1A,EDEM1,NLRP6,CTTNBP2NL,ACTN4,OS9,RIT2,SLMAP,MCHR1,KCNIP2,HGS,CHGA,MAP2K1,CCR1,PPP1CC,PRKCB,SUMO1,FCGR1A,RAP1B,CRHR1,AZIN1,CCL21,MIR20A,GHRL,BAG3,NDFIP1,CBL,ATP1B1,FIS1,PICALM,ATP1A2,RAB3A,DLG1,SLC35F6,KCNC1,CASK,SLC43A2,CCL5,KCNB1,IL2RB,RIMS3,RAB4A,THOC2,UBAC2,WWP2,HCRT,PREPL,ATP1B3,CREB1,SFRP1,ARFIP1,IER3,PPIA,DAPK1,CDC42,PTGES,CRYAB,PDCD5,RAB9A,YWHAH,RASL10B,KCNJ2,CCL3,MIF,IL12A,HTR2A,REN,INPP5K,LILRB1,APLN,CDK1,HSP90AA1,OPRM1,CDK5R1,FGF12,PARD6A,SNAP25,ACHE,CAV1,KCNAB1,CLIC2,HTR1A,MAVS,FURIN,FKBP1B,NDUFA4,MEF2C,GPR35,CAV3,AP2M1,EFNA5,MIR208A,PKIG,OPHN1,RBM22,MRLN,CNKSR3,SNX3,TACR1,IL4,SLC38A3,AP2A1,ARPP19,ATP2C1,CD4,CD81,ARL6IP5,MIR146A,PSEN1,STC1,SLC7A11,APBB3,SCN3B,SMAD3,KCNJ10,XPO1,MIR24-1,ISCU,CD63,PRSS8,RHBDD3,KLRC2,CRHBP,CCN3,ASIC1,RAP1A,VMP1,CLTRN,SELENOK,LACRT,YES1,RAB33B,MIR205,SYK,RINT1,CLU,DERL2,SCG5,TMBIM6,NKX3-1,PRR5L,MIR208B,FCGR2B,TESC,S100A8,STK11,SELENOT,STAP1,CCDC32,NPSR1,NHERF1,MAP2K6,CCL2,SYP,SYNGR3,HCLS1,PML,DNAJC1,SYBU,IL15RA,TERT,KCNJ8,DRD1,CACNB4,NFKB1,CHRM3,P3H1,PLP1,SRI,GNA11,FGF13,CD2AP,CD38,DMPK,LAMTOR1,PLN,RAB5A,NLGN2,TLR2,KCNJ3,G6PD,MIR183,SLC12A2,TMEM97,GRM2,YIPF5,C2CD2L,PICK1,AKAP8L,SFTPD,CCL19,VAMP3,ADGRE2,FEZ1,PPIF,CACNB2,MIR34B,DYNLL1,PGRMC1,MIR873,TIAM1,CD47,IFNG,NLGN1,P2RY12,ROCK1,RAB8B,SESTD1,MEF2A,NEO1,SURF4,OAZ3,MIR143,KCNJ11,NRDE2,MTMR2,SRC,CALY,STAC3,UQCC2,ANGPT1,PPID,PHB2,PSEN2,CBLL1,ATF4,TM9SF4,STX18,THY1,PIK3CG,VAC14,CD200,PDE4B,FASLG,HNRNPK,LEP,COX17,SNX17,IL15,NFE2L2,FGF23,AP2S1,PRELID1,MECP2,FABP5,SLC38A1,VEGFA,SLC38A2,NF2,FXYD6,LYPLA1,PRRT1,UBASH3B,PIK3R1,RAN,SNCG,PIK3R2,MIR301B,CPLX1,DNAJC5,OSM,GSTO1,MKLN1,LYSET,AMIGO1,OPRK1,BORCS5,STIM1,STOM,BET1L,CAMK1,MIR153-1,EP300,IGF1,NFKBIA,UCP2,ENY2,PDCD10,ABCB1,PACSIN3,CAMK2G,SIRT7,PIP4P2,BOK,CALR,RAB3D,GH1,CTNNB1,SLC1A2,HYAL2,BAK1,TXN,TCAF2,MAP1B,NPVF,CXCL11,RETN,RALA,OXTR,DPH3,P2RY4,PPP3CA,UBE2G2,WNT7A,ARFGAP1,SLC6A1,TBC1D4,AKT1,IL1B,TGFB3,MIR92B,GRB10,SMAD4,PFKFB2,SELENOS,DRD3,SLC25A31,ITGA2,ATP8A1,PPP3R2,TSG101,KCNS1,STXBP1,JAK2,PTEN,NR1H2,PLA2G5,PCSK9,NRP1,GSK3A,PRKCE,CPLX2,CRY1,BAD,SLC4A8,MIR448,LCP1,RAB27A,RIOK2,XBP1,SNX12,MIR206,CD14,GNAI2,ANP32B,PID1,NUP153,PLAA,ATP5IF1,CARTPT,SOD1,SLC8A1,CNR1,MSN,CXCL9,RAB23,MYO6,MIR223,ACVR1C,PEA15,ACSL4,GPM6B,LRRTM1,RNASEL,FGR,MIR185,MX2,FCER1G,DPP10,IL12B,BAX,ERP29,CSK,RSAD2,AHCYL1,EFCAB7,IL6,MMP9,BGLAP,ACAA2,MIR107,GNAO1,PPP1R12A,PRL,KCNA2,MIR186,AKT2,CA2,UHMK1,CPLX3,DMAP1,VDAC1,TRPC1,PRNP,BVES,MIR130B,SNTA1,OXSR1,CLIP3,FLOT1,PPARA,SNAP91,VEGFC,CHMP2A,LYAR,IFI27,SAR1B,EDNRA,VPS18,UCN,MIR210,SNAPIN,CD36,MIR129-1,FERRY3,NUS1,MIR33B,LGI3,KCNIP3,NOS1AP,TNFRSF1B,PCK2,PLCB1,TLR9,GNAZ,ILDR1,MLLT6,HDAC3,MIR148A,CREBL2,RGCC,LILRA2,SYT4,SFN,SELENON,EHD4,CACNG3,INHA,LPCAT3,MIR21,HADH |
| 4.531e-15 | -33.03 | FOLR1 (folate receptor alpha) | protein interactions | 2348 | 226 | 119 | 19454 | 5460 |
LUC7L3,RPLP0,ZCCHC17,LMNA,RPS14,SLC35F6,HSPA5,RPL4,PRDX6,RPL27,DDX46,TUFM,CFL1,RPL26,SUB1,RPL7A,PSMB2,RPL22,RPS12,RPS20,TUBA1B,RPS3,RP9,RPL15,EEF1A1,CCT5,RPSA,RPL17,RPS13,ARF4,HNRNPK,RPL23A,RPL3,TCOF1,MAP4,RPL10A,RPS2,SNRNP70,RPL24,EIF5A2,GAPDH,HDAC6,ATP5MG,TOP1,RPL35A,RPS16,ALYREF,RPL32,SRP14,RPL12,MYL6,RPL27A,H1-5,CSRP1,PHB2,EEF1G,GPC1,EMC1,DDX5,SF3B1,HSPA8,RPS28,SNRPA,SERPINH1,HSP90AA1,YWHAZ,H2AZ2,CCT2,RPS29,RPL39,HNRNPC,CUL3,ERH,RPL10,RPL19,ACTB,TUBB,RPL35,AKR1C2,PRDX2,TAGLN2,RPS9,RSRC1,RAN,S100A6,RPL18,RPS23,RPS11,TUBB4B,RPS7,EEF2,ISG15,ACTN4,RPL28,RPS4X,HNRNPF,SRSF7,SRSF8,ARGLU1,CCT8,HNRNPA2B1,SLC25A5,HSPD1,RPL31,HSPB1,RPL23,MT1X,HBA1,RPL6,PRDX1,HMGA1,HSP90AB1,SNRPD3,TCP1,RPL7,RPLP2,SRSF1,PHB1,RPL8 |
| 4.630e-15 | -33.01 | DNM1L (dynamin 1 like) | protein interactions | 10059 | 322 | 156 | 19454 | 5460 |
RMDN3,ARF1,APEX1,ERH,OTUD6A,RBBP4,TAGLN2,PRDX2,TMEM183A,PSMA4,RAB11A,LDHB,SCG3,SFN,HNRNPAB,NIBAN2,FIS1,PFDN2,YWHAZ,CKB,CCT2,AKAP1,RAB5A,XRCC5,EXD2,DDX39B,SKP1,PSMC1,SAP18,PXMP2,GPM6A,EEF1G,TIMM13,MTX2,ATP6V1C1,TOMM22,PPT1,KCTD12,DNM2,WIF1,COX14,CCT7,PPIA,AASDHPPT,SUMO2,EIF2S1,EIF3D,YWHAG,ATG7,YWHAH,VPS26A,MARCHF5,RAB32,YWHAB,PEX3,AHSA1,HAX1,PDIA6,RUVBL2,CCT8,PABPC1,SAR1B,HNRNPDL,RPL28,RUVBL1,KRAS,EEF2,ACTN4,TRAF2,SOX2,RANBP1,MIEF1,RAF1,OTULIN,CYB5B,NME1,PTRH2,RAB4A,CHMP4C,PLS3,CA14,PSMC5,RTRAF,GANAB,EIF4A3,SF3B6,CCNF,OPTN,UBE2L3,TXN,RAB14,BUB3,LDHA,MGST3,SUB1,CARS1,AKT1,MAT2A,CAP2,UBE2H,PSMG3,PRDX6,SQSTM1,ARFIP1,RAB9A,MAVS,SYVN1,RPL27,BAP1,SOD1,RPA3,TOMM20,FBXW7,PDHB,CCND1,PSMC4,SH3GLB2,RARS1,HNRNPH3,HSP90B1,SAMM50,CDK1,RPA2,TES,ARL10,EEF1B2,PTPN1,RPL12,AIFM1,CDC5L,PLGRKT,MYL12A,PRNP,FZR1,COPS5,EDEM1,SLC25A46,PGAM1,USP15,DNAJC7,H2AC4,MUL1,HSD17B10,CPNE2,ABCE1,SFXN1,FKBP8,RAB3B,ACTR1A,MAP1LC3B,CENPM,MTCH2,RRM1,PSMC3,APEH,ILF2 |
| 4.799e-15 | -32.97 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 12479 | 3857 | 19108 | 5553 |
MVD,RNF26,STAC3,AP5S1,RIMOC1,CHMP5,CTLA4,XPO5,POLR3H,ANAPC15,CNP,RALYL,MARCHF5,COMMD3,TCEA1,HS3ST3A1,PPT1,SEC61B,CLCA1,THOC3,CD63,SLC25A26,ATPAF2,MPIG6B,PPM1D,DPPA2,HACD4,SSBP1,CMTM6,ZNF200,KLC2,CLIC4,RPS29,PIGK,UQCRQ,GIT2,MTAP,SNAPC3,ZNF304,DHRS4L1,CDK1,TRIM24,PSMD6,FZR1,TBC1D16,SESN2,ABHD16B,TFDP2,SVIP,MACROD1,DKC1,DCP2,USP30,FZD6,CCND3,EIF3E,SOX14,HDHD3,CSGALNACT2,AKR7A2,PAOX,GJC1,ZNF267,THOC1,KLF3,SLC25A3,ZNF609,YIPF5,SGF29,TESPA1,SAYSD1,APOBEC3B,RPA2,TMED9,SUFU,RING1,ZBTB26,RPS14,GNAQ,TCOF1,MED27,MCMBP,NUDT19,VASH1,ORMDL1,THAP2,TBK1,FBXO11,WBP2,API5,MGST3,ODAM,PLN,CYGB,VAMP8,SLC25A14,PDCD4,BECN1,COL3A1,CYFIP2,MXI1,BORCS5,NME1,MED30,ACKR3,KRT8,PDYN,VSTM2A,MED4,LMO3,PNPLA4,RPS9,MYT1L,TIMM8A,RBMX2,GLO1,RNF8,ZMYND11,RCE1,FOXP3,DGCR6L,STK16,SOD1,MAMDC2,YBEY,MPV17L2,IRF1,PRPF4,NUP62,RPL35,SLC18B1,RPL23A,CTSC,DHRS7,SLA2,SSR3,SUMO2,TOM1,TP53,RGS6,KLHL15,HMGA1,ASRGL1,STAU1,H3C1,UBASH3B,ISCU,TMEM45B,WDR6,H2AC13,VPS26C,SIGLEC5,GJB1,CASP4,MORC4,ASCC1,PGAM1,MPDU1,TXNRD1,CTNNB1,MPV17,SNAP23,CERS6,CXXC1,ATG9A,MCL1,SRSF4,SC5D,ASIC1,VEGFC,IRF7,RINT1,UTP25,SNAPIN,CDC37L1,IQSEC1,FBXO7,PATE4,PCCB,POLR2F,CSRNP1,PPFIA2,E2F4,IFT172,MOSPD1,AP2M1,RETREG2,ESD,CCDC85B,SYNJ2BP,APEX2,SPC24,SNAPC2,ZNF32,GPX4,MT2A,JPT2,EIF4E,RANBP6,MGST2,BARX2,BAD,LURAP1,FMO1,SYT4,RPS15,HMGB1,CLP1,LRRC8C,COX17,ZC3H14,APBB3,SDR16C5,TECR,PSMB11,TLCD4,YIPF3,GLE1,SELENON,CCDC106,TRIM6,FBXL19,PLAA,TENT5C,SSNA1,GPRASP2,SKIC8,TMSB4X,MAD2L1BP,HBEGF,CNOT6L,SETD4,RPA3,POLR1D,TMX3,SNX1,MTMR12,ELP3,OSGEP,NIF3L1,IREB2,MBD5,MME,CD3G,PTS,TSSC4,STARD3NL,NDFIP1,PYDC2,PEX5L,PPIH,BTBD10,TCF21,ZNF507,MIA2,NUP50,E2F6,RBBP7,DXO,TGFB3,RPN1,CHST10,MTHFD2L,TRAF6,CCNB1,SRP14,COX7B,SKAP2,PICK1,FOXP1,KIN,HOXD12,NDUFAF4,PLSCR3,BOLA3,QPCTL,SUCLG2,FAM222B,HSD17B6,RPS26,TMEM190,SMUG1,SGTA,CNPPD1,TMEM160,RIOK2,COX20,THAP1,SRSF8,FAM193B,MRPS18B,FGF1,PTGDS,IER3,GADD45G,LGALS8,CRLF3,SEC22C,RPL27,PCYT1B,IRF2BP1,TAF5L,RRP7A,B3GALT2,IDE,TAPT1,GAPDH,MND1,DERL1,USP39,FGL2,ADRM1,GDPD3,CREB1,CINP,EIF1AD,DTL,IK,FAF2,NAA15,CDC7,HNF1B,SRARP,PPP1CC,JUNB,SUPT7L,TMEM168,MIF,SPTSSB,JADE1,STIM1,LIPA,ATP5F1E,CCAR2,RBM42,JAML,NKX6-2,RPSA,SLC31A1,EGLN3,APOBEC3H,UTP23,PPP1R26,VPS26A,SEC61A1,DHX38,MYBL2,FMC1,SNX24,LSM4,H2AC7,HIRA,TAGLN3,PSMC3,AMELX,SCNM1,TERC,UBE2L3,RUSC2,TRIM23,VPS26B,DYRK1B,MPHOSPH6,NEK7,HYAL2,TIMM17A,SSH3,PKIB,SSBP4,ELOF1,IKZF2,STK38,MTM1,RPL37A,NDUFA2,ZKSCAN1,PEBP1,CYB561D2,SPCS3,PMPCA,OSR2,NFKBIL1,H2BC17,FTSJ3,HEBP2,CBR3,CRBN,SP2,TMA16,MTG2,ARMC7,POLR2B,PHF23,SAP30BP,GTF3C3,VAMP7,RPL3,IRF3,HNRNPAB,MAPK10,AATF,AMT,SLC16A1,GLT8D1,ZNF787,PHB2,ABCE1,RDH10,TOPBP1,HEXIM1,FOS,USP6NL,THOC6,RFX5,B4GALT4,GRIK1,STARD13,CHPF2,RAP1B,TOR3A,SMAD9,FERMT2,IRAK4,BACE1,POLD4,TNKS2,TMEM39A,LRIF1,CCDC186,PSMB4,MGARP,PGAP4,CDKL2,RBM3,PDF,OLA1,TIGD7,CDKN2D,ZNF451,SYNGR3,COMT,C2CD2,GABARAPL1,FUT8,MTRF1,FBXW11,CHTOP,SERINC1,RUVBL1,NEDD8,PABPC1,REEP6,CAB39,ELOVL3,PHF13,LRRC8D,MDC1,NRM,LST1,MOXD1,TCP1,TRIM22,RAB6A,ACSS2,METTL15,MRPS18C,DERL2,LDHB,RSAD2,SEC11A,CDC23,PIGW,RADX,TMT1A,THBD,DRG1,TNRC6C,REEP4,UBE3A,POLR3B,SNRPA1,RAB11B,ATP5F1A,MGAT5B,EMC1,HSH2D,FGF13,PSMD1,CACNG3,MRPL33,RAB32,S100A6,NEU1,ATP5PF,RPP25L,FLCN,SYVN1,PROX1,CST11,KGD4,RUVBL2,SIAH2,EIF5A2,MREG,CCR2,ZBTB16,ACHE,LTBR,RLIM,ISG15,SPTAN1,CHMP1B,NKIRAS1,B2M,PIGC,JPH4,AMACR,EI24,CX3CR1,WDR83,UBE2E2,SNRPE,HFE,SAMM50,EHBP1,CEP85,FBXO22,GABBR1,FXN,TWIST2,MRPS26,DPEP3,ARG2,TFB1M,CTNNBL1,CLBA1,ID4,UGCG,HSP90AA1,SYT2,FOXN2,MSX2,RFC4,QRSL1,AGER,RHCG,FAM53B,EYA3,CDKN2AIP,MYO6,PGM1,CTTNBP2,AP3S2,ANKRD50,YTHDF2,PSENEN,GFM2,RAB1A,CYP4F8,VAC14,MBL2,MXD1,ZDHHC8,G6PC3,OVGP1,GNB4,TSNAX,DNAJB4,GTF3C4,TIMM10,EMX2,AUH,EID2,ALB,HDAC5,NDUFB5,COL1A2,IKZF5,ACADSB,MARCHF3,NEUROD6,RERG,CRYGB,RAD23B,CFAP91,ZNF263,AFTPH,GTF2H2,TIRAP,TRNP1,PPP1R12A,CDK17,CIMIP2C,ZNF473,PTEN,TM9SF1,PPP1R11,BTG3,GABRB3,ERRFI1,BTG1,LCORL,OLFM3,SYBU,PAPOLA,SMAD1,RNASE6,PYM1,TUSC3,DPY30,ADRB1,RMND1,CCN3,G0S2,MIOS,IL15RA,EMP2,CHAMP1,MLF1,ANAPC11,CWC15,PTPN11,AGR2,UBB,RNF152,PEG10,NUS1,LAMTOR1,ZNF652,PSKH1,IL12A,TIMP3,NUDT9,RPS17,RPS5,KLK3,SYCE3,SLC25A44,PDHB,HRAS,FUNDC1,HOXB1,CDAN1,TIMM23,CSH1,PRDM4,EMG1,TAX1BP1,NUP153,MGME1,GLRX5,NDUFS2,RBM22,GALC,STAP1,BUD23,TMEM123,CNOT2,URAD,HNRNPL,RPS6KA4,PGRMC1,SFT2D2,TVP23B,YPEL5,HTRA2,SERPINB10,STX1A,RAB9A,CHMP2A,VGLL2,CHST2,MCOLN1,AVPR1B,SUMO1,POMT2,GPC4,MAF1,AGK,ACACA,CDK9,NAB2,FUT1,UHMK1,LGI3,CCR5,WDR37,APH1A,ADK,ARF1,TEX19,GNB1,NQO1,PDSS2,MT1A,ACSL4,SCAMP5,THG1L,CBL,APOBEC3A,C1D,KXD1,LYZL4,SETD3,METTL6,PMM2,PRDX1,SF3B4,UGP2,CYTH1,CAPG,H2AC6,STARD4,POR,CRISP1,TBC1D5,WNT7A,OCRL,COP1,PPIC,TRIB1,PRPF31,DNTTIP1,MYCT1,CISD1,RABAC1,LYZ,CD1D,DBT,SELENOF,GTDC1,PTRH2,SPRED2,TRIM3,KMT5B,BFAR,CNOT7,CYBC1,UGT1A1,BANF1,BCCIP,TRA2B,CCR7,INPP5E,CNOT6,LDB1,SLC4A8,RCHY1,PDE7A,CREB3,B3GNT2,SOX21,JKAMP,CYP2C8,RAB3B,RPRD1A,EVA1A,PRCC,DLST,CD274,TMEM14B,TLR2,DYRK1A,WDR44,PSMD14,RBM5,TRIM35,OARD1,NOA1,MYRF,PRDX4,CARTPT,TES,RAB40AL,UBE2D1,CLRN1,BOK,MED10,IFRD1,BHLHE40,PPARG,TIMM29,CHP1,H1-5,FAHD1,RPAIN,SCML1,ABCF1,CLN8,SELL,RDH11,MRPL11,GFM1,ALKBH4,F9,ICA1,TRAM2,UQCRH,ATXN1L,NR2F6,RBM7,RAB14,CAPN2,LAMTOR3,CYP2D6,MRPL53,ALG11,RC3H2,RNF113A,SLU7,SLC35E4,CD2BP2,SLC25A32,AGTRAP,FTL,ADH1A,OPRM1,NSG1,CIART,CD2,UBXN6,NDST3,DDIT3,TSEN34,SERTAD2,ZNF790,GCHFR,FUNDC2,DNAJC2,NDUFS6,GPC1,FABP12,SARM1,TUBG1,HCFC2,RMI1,MEF2A,SGIP1,DNAJC7,GOSR2,TP53INP2,SFTPA1,RERE,ZBTB45,NEUROD2,GTF2A1,PAX9,HNMT,BET1L,CSNK1A1L,PSMG2,FYTTD1,HDAC11,ZNF436,EFNB1,CYB5R4,DCTN3,RGS19,MRPS23,MORC2,SLC35F1,PHF12,CDK6,GZMK,PRPF18,TMEM30A,PIR,ZNF596,SLC16A10,FERD3L,PLCB2,GDI2,MYD88,ZNF24,UBIAD1,PYROXD2,DAPK1,ACTB,ASF1A,PPP1R8,SLPI,PPTC7,SERTAD1,ARF6,GABRA1,DNM2,GTF2E1,CLCN6,CYP2C9,TOR4A,ELOVL6,SERINC3,F10,CRTC2,MRPL51,FSTL1,PFDN2,RGS10,ETV6,STAT1,SEMG2,RACGAP1,GK5,NDST1,TRIM34,THAP7,MEPCE,UBE2K,DHRS3,LDHAL6B,ETFBKMT,DHRS1,SKP1,PLA2G4B,CGAS,UQCC2,MAEA,KPNA1,COX16,PSMA4,UQCC3,POLR1B,BORCS6,TULP3,SLC35E1,TIMM13,SYNDIG1,PITHD1,MTPN,HP,RPGRIP1L,HSPB1,GCFC2,RPL23,SRPRB,NR0B1,SPINDOC,PRL,SLC22A17,SLC51A,HACD2,WDR82,YKT6,CDC20,LYZL6,PRIM2,SRP72,CCNA2,HSP90AB1,FURIN,GTF2H5,CAND1,TREML1,ERO1A,MTMR6,IFIH1,DCAF16,LBH,ATP6V1G2,AIF1,SDCBP,EZH2,FOXP4,PACRG,MED22,SLC25A10,VAPB,HR,SRD5A3,TAS2R16,GSKIP,RTCB,RGCC,CCNF,RBP5,HSCB,MTERF2,SLC6A4,RARRES2,TFE3,GGTA1,TIMP1,NOL4,FAM110B,SLC17A5,ZNF574,TAFAZZIN,DGCR8,RNF41,CALU,CLVS2,COIL,PAX6,PEA15,MAGEB1,SNRK,SNX33,POLR2L,NDUFB6,SURF2,UBE2F,LARGE1,TSN,NDUFAF2,LPXN,SPIN3,ZGLP1,TRIQK,OAZ2,TXNDC12,PRKCE,TMEM95,KDM2A,PCBP4,PIP4P2,PKIG,RAB23,PPP1R1B,DDX46,ZMAT3,UAP1,MLH3,IL23A,ARRDC3,RAB22A,EED,TSEN54,GABRB2,UBE2A,ACTL6B,LMAN1,AZGP1,ATRAID,NOPCHAP1,AHSA1,CYP2C18,HTR2A,SH3GLB2,UFL1,UQCR11,MAGED4B,GTF2I,DNAJC1,CDC16,ACAT1,NUBP2,ADCY3,SART3,EPHX1,NOP58,H2BW1,GPX7,BET1,VEZT,CDC42,MAPKAPK5,MAP1S,TMEM199,HMGN4,TXNRD2,TRAPPC10,ZRANB2,ZBTB17,ZNHIT3,SERPINI1,UBL5,PSMA6,OXCT1,CAV1,ANAPC13,SCD5,CSNK2A1,TSSK1B,RHOG,BLOC1S5,OAZ3,MED9,SNX3,SNAI3,HUWE1,NOP16,APOBEC3C,POU5F1,THUMPD1,RAB30,SMAD4,ZNF511,MBLAC2,TOMM6,CFAP68,UCHL3,CPLX3,PRKACB,PNMA1,CIPC,APOBEC3F,RNF146,GSTK1,UNC45A,MAGEB10,ABHD12,GCLC,MLLT6,RAB2A,SLC25A45,NHEJ1,STK11,CDK4,OAT,POLDIP3,PLEKHJ1,COG1,DDX42,FCHSD2,NEO1,NHP2,DOLK,MOSMO,ZMPSTE24,COPZ2,COX6A2,LYRM2,FEZ1,ZNHIT1,BRD3,ROCK2,ELOVL1,BATF,FAM98A,PTGES,GNA11,KCTD15,FABP4,NUP37,ALKBH3,DDX50,PREP,UTP6,TDP1,TSG101,PGAP2,PPP2R5E,GAL3ST4,KLF12,FLOT1,OPTN,SSBP2,SMARCD3,ATP6AP2,TPST1,SPG21,TMEM74,ETFRF1,CPT2,MTHFS,KLF1,HSPA8,PELI1,FEM1B,USP2,PAQR8,DNAJC27,SPHK2,GRPEL2,CSNK2B,ZSCAN1,POLD2,NPM3,SPPL3,GPR37,CD38,TOX4,DUSP18,KLHL22,FAM3C,CYP7A1,WWP2,EMX1,RRAS2,CDIPT,BHLHA9,ALPL,CSNK1A1,ITK,PSMA1,GLYAT,SLC32A1,NRP1,MAX,SPP1,SYNRG,APOO,ATP5F1D,LYAR,MRPS34,NOTCH2,ING5,SELENOT,TSPAN15,ACADS,SMARCB1,RFC3,RMND5B,APPBP2,OPA3,CUL3,CFTR,CYB5A,FAS,EDEM1,GTF2H4,RPLP0,LIPT2,GTF2F2,SHOC1,TADA1,PCSK2,SESN3,RAB4A,TENT2,ARB2A,UBP1,SEC62,PYCR2,VLDLR,C9orf72,SMN1,SMAD3,MSANTD4,HINT2,GNAZ,SACM1L,EXD2,HINT3,MTF1,RSPH1,UCP2,CHCHD2,PCGF2,TAPBPL,RTN4,PIK3R1,RTRAF,LUM,NR1I2,TRIM21,PHF7,TMEM167B,STAMBPL1,ADH1B,DNAJC3,MIR29A,SERPINA3,LPAR2,DVL2,ZDHHC24,IP6K1,ANKRD10,PRELP,EDEM3,GLCE,MSL2,SP4,IMP3,HSBP1,PTDSS1,CDK12,DEDD,GSTM3,CD36,PTHLH,LSM3,LHB,TSPYL4,PSME1,ELP6,MRFAP1,STAMBP,SUPT3H,HERC3,ZHX3,LGI1,LLPH,COPS4,GK2,USP8,AKAP1,BTG2,KPNA2,IER2,NUP35,ZDHHC16,DCAF4,BAZ1B,SHMT1,SLMAP,NDUFV2,UPK1A,RRN3,LAMP5,RND2,TRAPPC3,PICALM,SNX14,MGAT4A,ATP1A2,ACAA2,CHCHD1,SDC2,SHPRH,RBM23,MOB3C,CDKN1B,GALNT12,G2E3,MEF2B,GPD2,TCEAL9,CIRBP,SEMA4C,HINT1,RALGAPA2,FAM162A,GTPBP2,CRYGD,PRELID1,SMG5,UBLCP1,SYNCRIP,GABPB1,PPIL3,SNRPD1,CPNE2,CYP4V2,RNF11,ARCN1,MRPL18,CYP1A1,SF3B6,MECR,ATAT1,SNX20,NPR2,NPC1L1,GINS4,TMED4,FAXDC2,SRSF12,CXCL1,OGN,KLK6,LMO4,MACO1,ATP1B3,PRRT1,IZUMO1,MRLN,TNKS,CRYAB,FEM1A,NCALD,APEH,CENPP,SEC63,TUFM,CALML5,TRIM63,CCM2,MFAP1,TCF23,MIR29C,RPL8,PCYOX1L,DRD1,ZBTB2,RASL10A,ZNF668,FITM2,DDX1,MID1IP1,LARP4B,SNAP91,EID1,RPP14,MFN1,NCKIPSD,ACP2,INPPL1,RAD21,RBM27,ATF3,RNF122,SSU72,TENT4A,LORICRIN,CETN2,FCER1G,TMEM38B,POP7,GRPEL1,SLC35A2,PHAX,THY1,SOBP,DUSP6,MIEF1,TMCC1,SFXN1,INO80E,SLX1A,BCL6,RB1,TRIM11,SLC25A20,CDK7,TCEAL7,VMP1,SAP30L,STUB1,OPRK1,PARM1,TOR2A,REP15,RAMAC,TST,DHX15,PXYLP1,RPS27L,RP9,DRAP1,PIAS1,FOXS1,NDUFS8,TRAPPC6B,TCIM,DCAF11,SLC35B3,MAK16,NKX3-1,ALKBH2,OGG1,CYP4F22,ATP5MK,HIKESHI,TTC4,MRPS18A,PCNA,RAMP3,HNRNPA1,UQCRC1,ZDHHC4,MOBP,SNRPG,TERB2,UBE2G2,DUSP1,THOC2,RNF148,RSL24D1,HSPD1,DYRK2,CD58,CYP11B2,SEC22A,VPS72,ATP6V1E2,RIC3,PREPL,FAM156A,PARD6A,ITM2A,SCML2,NDN,CHST1,XAF1,ATP6V1A,ZNF397,LIG3,PDAP1,H1-10,PLG,FAM169A,ATG101,SNRNP70,UBE2V1,CCHCR1,G6PD,KCNIP3,CLDN9,CLPB,ERLIN2,CMPK1,CYB561,ITGAV,NCOA5,GPR15,PSMC5,TMEM59,TERT,CDC73,SLC2A1,COPE,GLYATL3,MATR3,H2AZ2,SLC25A24,SLC25A23,CTDSP1,TYMS,H1-6,SOX2,DCUN1D3,CMAS,ZNF593,DLG1,NSMCE3,FOXJ3,OSTM1,PRKCA,ALOX5AP,SIGMAR1,SS18,SETD7,WDR11,COX7B2,SNAP25,FKBP1B,GPR137,ABHD5,ZCCHC9,DAG1,CRABP2,ZNF688,MAGED2,SLC35C1,DNASE1L1,BCL7C,FMO3,RRAGA,FKRP,IL1B,CAMK1,CDC42EP2,RPL24,SLC11A2,ZNF592,BCL2L1,CHRDL1,CENPW,MORF4L1,CSTA,NAPG,PYGB,RAB39B,PIH1D1,INPP5K,ANKRA2,ACO1,ELK3,MTDH,SAMHD1,RPL18,ATP2C1,SYNE4,BPNT2,PHF21A,PPM1G,ATL1,SQSTM1,ZBTB14,ATP6V0B,PDE2A,ST3GAL1,NFYB,MYG1,CCNI,SCG2,EEF1AKMT3,BMPR2,DCK,MRPS16,POGK,BCL9,SLC25A21,TFCP2,TAF9,ZNF526,GSK3A,PDIA2,CERS2,KDM4B,ARGLU1,SEC23A,SLC39A13,ATP6V1G1,SPMIP9,JAK2,WDR12,PPP5C,ZC4H2,PLD3,CD1A,DIO1,DDX23,TFG,SRC,ZNF805,NTF4,TMEM209,SEC13,KCNH1,RPS10,LMBR1L,GPAA1,RAB27A,NDUFA4,GMNN,TMEM11,TRAF3IP3,ARFGEF1,BRAP,GPX1,VIRMA,RAB5C,CRADD,POLL,SYN3,GHITM,RAB35,CHCHD3,PRKCB,SLC25A28,RHOBTB3,PEDS1,CNIH1,STX12,MMD,COMMD6,SORD,ARMCX2,TM4SF20,CMTR2,SRSF1,TRAPPC3L,RND3,DHRS4,XPO1,LYPLA1,AVL9,SLC35A5,RBBP8,PHACTR1,DES,IGFBP3,CTNNA2,NKAP,TRIM5,CASK,RPAP2,PHYKPL,PLAC8,PSMB7,SLC35F6,CSTF2T,CAPN1,VPS28,SMAD5,VCPIP1,COQ8B,AQP11,MOV10,GGH,ZFP1,WDR77,COX6B1,SLC35D1,RPL27A,CMA1,CD1E,TCEAL1,RPS12,MSMB,B3GALT4,MIR9-1,TRMT5,GNB1L,ARL4A,FBXL3,ID1,CREBBP,YES1,TRIM37,CENPL,SSBP3,MTRES1,BOLA2B,HNRNPF,AGPAT5,CLK1,MRPL50,BTF3,STX11,UCKL1,METTL21A,ZNF322,GNAI3,RNF10,SIN3A,FABP7,CXCR4,TBC1D1,LMNA,RNASEK,KIF1C,DMTF1,MKKS,FAM118B,NTMT1,DFFA,SDS,SATB1,MT1X,SFRP4,CLIP3,EEF1G,VWF,NFKBIA,ABCB9,SFTPC,LAMB2,SNAPC5,ARL6IP6,MFAP3L,PABPC1L,DISC1,USP3,POLDIP2,SH3GLB1,IL2RG,SEC22B,CITED1,SAP18,ACOX1,COX7A1,IVNS1ABP,TPD52,PTPN1,FKBP8,PCGF3,MRPL13,CPLX2,FOXP2,PGS1,TRAF2,ATP5PB,HINFP,NSFL1C,HCRT,TCEAL8,NME4,RNF20,ACER3,UBN1,VTI1B,ACTL6A,IDH3A,ESS2,HSD17B8,CBFB,MRPL22,NUDT5,ITM2B,VDAC2,USP13,ECD,MRPS21,SERPINA1,HELT,RAP1A,ABHD4,URM1,DNLZ,SYNGR2,BCAP29,SELENOK,PIP4K2C,TRIM15,MMP14,SLC25A4,PPP3CA,KCTD10,SNRNP40,ENC1,SMDT1,SDHB,DTWD1,UMPS,RPL10A,HSP90B1,STK4,DELE1,IFRD2,ZNF174,FAU,RFXAP,ATP5F1B,ZNF740,HS2ST1,CDK20,MT1E,PGAP3,SSR1,RPF2,TOP2B,BCKDK,COQ8A,EAF2,NUP42,RNF5,NRDE2,CST3,SLC35G2,LACRT,RETN,RGS5,AKT2,CLSTN3,GRIA2,HGS,TRAPPC6A,NFE2L1,FASTKD5,CD46,MALSU1,ANAPC16,CCNQ,FGD2,ERP29,SASH3,NOB1,ETF1,PNO1,RAB33B,IGF1R,IZUMO4,OS9,TMEM147,CDKN2C,SERPINC1,HSPB6,PLSCR1,TNNI3K,MCPH1,CSF2,PLAAT3,TOB2,PLEKHF2,WBP11,KIT,RPP21,C2CD2L,ACOT6,CTNNBIP1,PRSS23,EXOSC1,MRPS9,RBM17,ZDHHC15,CD2AP,YAE1,POLA2,GJA1,AR,NRSN1,SELENOO,H2AX,EWSR1,ADIPOQ,SENP5,HMX2,KLHL12,MS4A7,KCNJ11,IDH2,ATP8A1,PCSK9,CPNE1,EGLN2,PARP11,GTPBP8,POLR3GL,NUCKS1,AGAP2,SMYD3,KHDC4,PAK5,SNX11,SYP,AGA,BIRC5,MRPL17,AHCYL1,MT1M,JUP,POLR2C,SF3B5,ORMDL3,NSDHL,FOLR1,PKP4,STK3,DSN1,ELAVL4,RPS3,GIMAP4,MNS1,MCM4,IRF4,TMX4,HEY2,ZBTB5,LDAH,RBFOX2,SCFD1,REXO2,VRK1,ACAP2,MAGEH1,RNF144B,SLC25A46,PNRC1,WRAP53,HNRNPA2B1,ACTN4,CLU,NUDT3,DNTT,MARCHF4,ERCC3,ACTR1B,ADRA1A,MPG,ZBTB6,ZMAT2,NDUFA12,HSPE1,CCDC86,SLC35B4,NFE2,EDEM2,HS3ST1,NMI,RSRC1,MPC1,ADRB2,NEK9,DCTN4,OLFM2,NLGN1,TCEANC2,SRXN1,FCGR2A,HAND2,COX11,SUPT4H1,ABCC5,PSMB3,SMPD2,TRMT6,CFL1,AP1G2,CMC4,CYP26A1,SMNDC1,LEPROTL1,S100A11,SAR1B,CDCA7L,HSDL2,DRG2,PIK3R2,LSM8,RPL17,CLDN8,TXNL1,CASP12,FBP1,CGRRF1,SPTSSA,EXOC8,SAP30,TLR1,VAMP3,SMARCE1,PRCP,MRPS11,DMPK,ACTL9,ISOC1,IFI35,RNF126,FAM241B,EGR2,RFXANK,RWDD3,STAT5A,DYNLT3,RAP2A,NAA50,RNASEH2C,RAB3C,SLC25A51,KDELR2,SIRT7,TRIM52,CXXC5,CREB3L4,HAPSTR1,CHST7,PSMD10,CTSK,SV2B,EIF4A3,AKR1B1,MNAT1,MTX2,APOC2,MED23,SMCP,SLC25A39,CAV3,RNF14,REEP3,TMEM177,PSPC1,YIF1A,FAM76B,PITPNA,HENMT1,PYURF,SPMIP6,SAV1,ISCA2,ZBTB18,ADSS2,SNRPD2,STOM,UBE2D3,CPT1B,CSGALNACT1,JAGN1,CMKLR2,MAP1LC3B,NUDT4,EMC2,PABPC5,TAF2,PFDN5,GLRA2,MAGEC2,MSH6,SNRPN,MRPL40,TMBIM1,DNAJC10,UBE2H,TNFSF13,PLEKHO1,CKB,MED29,IMMP2L,CACYBP,FAAP100,RHEB,NICN1,FOXC2,ADIG,ZNF319,MARVELD1,INPP4A,GPNMB,VPS33A,PPIG,IMP4,SPMIP5,HLF,DPM2,KLHL7,RAC2,MED13L,COPS7A,NUDT12,PMP2,TRIM8,SGMS1,PAQR3,OSBPL8,RPL15,RPS20,PTPN5,DNPH1,SELENOS,GEMIN8,PDP2,CTDSPL2,RRM1,LRRC8A,TMEM106C,DUSP21,NR4A2,CENPM,RNF187,DUSP10,CCNH,NCBP2,UST,FAM241A,LDB2,FCMR,RPL9,GDE1,DENND2D,TRIP4,SRPK2,PDE9A,LAMP3,LSM2,FCGR1A,CTDSP2,VPS4A,LIMD2,CPSF4,ISX,DBR1,EGR1,VPS39,RGN,ARHGAP1,RHOB,RSBN1L,PDHA1,DDRGK1,TAF7,DTWD2,GNPTG,PRMT5,KLF4,CDK5R1,CMC1,OTULINL,HELLS,DDIT4,DNAJC30,NDUFS3,HIGD1C,TMEM174,CTBP1,ZNF692,NR1I3,DDAH2,CIBAR1,HAX1,ARMCX3,PPP2R1A,ANP32A,PROM1,NDUFAF3,SNX12,MMADHC,MCCD1,SURF4,DHX9,UBAP1,CHI3L1,PIP5K1A,TRUB1,MAP1LC3A,TMED7,ADCK1,UBE2I,ROCK1,EIF2S1,NUDT1,PAK2,PHC1,ZBTB38,CRHR1,ANKRD49,F2,TPT1,EIF2AK2,PXMP2,RAPGEF5,NDUFC2,PQBP1,PDIA3,TRMT1L,FMOD,DBH,MRPL34,PAFAH1B2,STARD7,CYP17A1,GLIPR1,ZCCHC12,CDNF,FBXO3,NUFIP2,MEF2C,TRA2A,TMEM100,GAS8,PYCARD,BNIP3L,MAVS,PPM1M,MZB1,FAM8A1,CBR4,POLR1H,FHIT,ARHGAP15,GPBP1L1,YPEL4,ST3GAL5,ELOVL7,COA4,ST8SIA4,MED11,CSRNP3,MAEL,TFRC,CHMP4C,SNX10,ZC3H11A,HBA1,KLK5,TRAF7,PSME2,ITGB5,SRSF7,AZIN1,G3BP1,ILF2,ARHGAP5,EIF3G,NDUFB7,SEC61G,ZCCHC7,SRFBP1,ATOSB,AQP4,TUSC2,CACNB4,RETREG1,HEXB,BST2,FLRT2,MRPL36,CYP11B1,SCG3,GCNT3,DLX1,GALNT1,F7,TMEM33,CALY,PTN,NAA35,GAPT,ARMC1,UQCRC2,TAPBP,NEK2,TMEM126B,COQ10B,LBR,MBD3,OVOL1,PSMB1,NAA30,ATP6V1C1,AIPL1,TIMM21,PPARA,BAG3,LINC02914,NOVA1,FBP2,PPWD1,SLC1A3,SMAD2,ZNF343,RNF139,KANSL3,CREG2,CCT2,CYBRD1,NGRN,LRP6,DET1,SLC66A2,NLRP3,RAB5A,PKIA,TNFAIP8,NGB,MRPL47,TRIM27,ALG2,CSRP1,GCA,FAM91A1,RXRG,CRYBA1,TNFAIP6,ZNF177,TWNK,WSCD1,CEND1,ASPM,SFN,PNP,SETD5,MAPRE1,BEND6,BIRC2,HADH,ASTN1,NCAPG2,PAFAH1B1,ATP5MG,ARPC2,PWP2,ERLEC1,RBFOX3,ARPC3,SPRN,KRR1,COX6B2,CYP4F12,GPAM,ZSCAN25,GSTP1,MRPL57,ZNF687,DNAJC25,STBD1,CBX3,SPON1,PSEN2,FLRT3,HAS3,TBC1D25,ILVBL,TOP3B,PML,RTF2,USP14,KARS1,TMUB1,TMEM179B,IGF1,TRIM36,ZFP64,RETREG3,NPC2,EEF1A1,KLF10,NFE2L2,TUBB,RNF115,TLDC2,RGMB,RAB11A,PRNP,CEBPG,GTF2F1,EXOSC3,BCL10,FAM210A,HOXB8,FRMD8,ZNF22,CLVS1,TIMM8B,CYTH2,CUL2,EDF1,CIDEB,INO80C,NXT1,RFC2,GABRG2,MYORG,STAR,STK26,NONO,PRDX3,EMC6,IPO8,STT3A,PSMA2,DUSP26,GIMAP2,MAD2L2,UFM1,CPSF2,TRMT61A,RPS4X,PSMD4,NPY,HYPK,TNPO2,CXCL14,SEPTIN7,RNF128,H2BC11,LDLRAD4,FNDC8,MEIOB,OLR1,ELOC,STX16,NTAQ1,HIGD2A,BEX3,CHID1,MAP2K3,MED17,BAP1,SLC39A7,PIWIL2,TMEM14A,ACP6,PRPF19,HMOX2,CCIN,RPS11,TRAPPC1,ASB11,BRD9,KCNG3,TBC1D17,IDH1,B3GALNT1,PTPN4,SELENOP,GON7,VXN,BOLA1,TPBG,AKAP8L,ZNF770,PGA4,NECAP2,TLR8,FKBP1A,CCAR1,ING2,TMCC2,CDC26,POLE4,RANBP10,SERTAD3,CH25H,MYO1B,VIPAS39,DUOXA2,RNF167,ISG20,TMED3,METTL14,TRAFD1,CTSD,KBTBD6,CTNNA1,STRBP,VTA1,GCC1,EIF2B5,ZNF622,RPL4,ZC3H7A,TOP1,UBXN2B,RETSAT,ZMYM2,TBC1D24,LILRA3,SHOC2,MAP2K1,HNRNPD,SERPIND1,RAB8B,PLEKHF1,PPME1,RPS2,TMEM106B,TAB2,STOX2,VKORC1L1,ZNF821,CLPX,ANKRD6,NFYA,LSM5,ATF1,OST4,PGR,FAM53C,FAR2,RPS27A,ABHD17A,LYSET,DIPK1A,ZDHHC14,PHF1,ARHGAP21,MTMR2,TAF10,ETFB,CCT8,EMC8,TGFB1I1,DPP4,MLF2,FADS2,TMEM59L,LDOC1,CTSA,SPOP,IFNAR1,NECAP1,ZMYM6,ZSWIM7,PPP3R2,PSMB6,TRAPPC13,USP15,PEX26,RBM18,INTS10,NXT2,GANAB,CNPY3,PEX13,PADI2,STX8,AP1AR,GPR89A,CHMP2B,HBP1,DCAKD,CD40LG,SLC25A12,PPM1B,EXTL2,HILPDA,PKNOX1,ZBTB39,ZNF513,ATP1A1,FRA10AC1,PSMC4,SERPINA5,AGPAT1,ABITRAM,CSTB,UBE2N,SGMS2,TMEM87A,SF3B1,ZNF326,EP300,PLAGL1,MGMT,FKBP14,TESK2,RGMA,PET117,PDCD5,GNPNAT1,LAPTM4A,RALA,FCF1,CCND1,POLR2I,TPPP,MRPL12,CCDC22,HSPA13,XPOT,CYP27A1,MRPL49,TNFAIP3,MITF,ZNF175,COX10,RASD1,CFL2,HMG20A,DNAJB6,KRAS,CTSB,KCTD17,PDIA6,RBM38,PTP4A2,TOX,RNF7,USP5,ELK4,SWAP70,ATP6V1D,LYNX1,MCM3,HSPB8,LMNB1,SNRPA,UBE2V2,TESK1,HNRNPA0,ZC3H15,TXNL4A,ETFA,PCK2,BAX,TACO1,TMT1B,SUPT5H,CWF19L1,SFTPD,SYK,ENY2,BCL7B,AP2S1,FXR2,HCLS1,TAMM41,CBX5,RAN,FKTN,POLR2D,KLF9,ZNF250,IL2RB,MRPS33,SMURF1,SMAP2,PPM1K,MRTO4,TSC22D3,SPTBN1,PPIL4,NDUFA5,UBL4A,LDLR,AP1S2,RPF1,ANKRD34B,H2AZ1,PAGR1,AIP,HSD17B3,BLOC1S2,TADA3,EMC10,FATE1,PLA2G15,RGP1,EFHD1,IFI6,TMPO,FBXL4,SHC1,KPNA6,CCDC134,RPS7,PRKD3,GFI1,DLAT,RBMS2,FDFT1,CMTR1,ROGDI,RBBP9,PSMC1,RPP25,CHPF,TTI2,TRAF3IP2,GGPS1,SYPL1,TUBA1A,TESC,RBM41,JRKL,PCBD1,PPP4C,GLOD4,ZNF280B,ZBTB33,CASC3,CNOT8,MSN,CD9,ARL4D,ZNF7,FUT9,ADD1,CPEB1,CNDP2,ESYT1,HARBI1,ZNRF1,H2AJ,NRSN2,ISG20L2,EEF1B2,FBXW7,DDX39B,RGS7BP,ST3GAL2,MMUT,SDHC,PHB1,CAMK2G,BORCS7,TEX264,RHOBTB1,BEND5,HNRNPDL,CCDC174,SUB1,UBE2S,GTF2IRD1,NAA11,TOMM70,RMI2,FOXD3,COTL1,VEGFA,ANXA7,EEF2,TFPT,SFXN2,IFI16,COX14,IL1A,RPRD1B,PAPOLB,H1-1,FEM1C,NOL12,GRIA1,RNF103,CCDC90B,ZNF189,MRPS17,MT3,GATAD1,CYP3A5,MRPS7,H2AC1,RDH12,OSBP,HPS6,TCF19,RPL13A,PDE12,SYNGR1,FGF10,P4HA2,GOSR1,KLK9,TAX1BP3,PHYH,FOXI3,TFEB,WDR20,RPL22,BAK1,CLDN14,ZNF207,IRF9,AQP3,SSR2,ATP5MC3,MTARC2,SLC25A5,DNAJC8,BRI3,TAF1D,ARL6IP5,RAB31,NRBF2,PMAIP1,CCDC3,SIX5,SELENOM,DCLRE1C,MMP9,EXT1,MAT2B,SMC4,NKRF,MED31,SEPTIN6,POP5,DCUN1D1,CCDC47,SCAMP2,UPF3B,RAB13,COMMD5,MACROH2A1,ZBED1,MYC,SPCS2,ST8SIA5,CHST11,SOX3,ACP5,PRMT6,STXBP1,ZHX1,PTPMT1,NOP9,PTTG1,GGCX,MYEF2,WASL,MSRB3,SIAE,FGR,PIWIL1,NUDT7,MDM2,NFKBIB,MARCHF9,ZNF671,EIF4EBP3,ARHGAP19,UBE2W,AURKAIP1,MLC1,NIPA2,CYP3A43,LHFPL2,CREBL2,USE1,FMO2,PYCR1,MIR214,CBX7,GHRL,USP38,LMO2,TMEM108,LACC1,NABP1,VAMP1,ELF5,EID2B,CYP2F1,FUBP3,COX6C,TLE1,ARMCX1,ARL14EP,E4F1,FOSL2,SRSF10,SHISA2,XRCC5,RHOU,MAGEA4,LTO1,GALNT2,RER1,HACD1,FKBP2,GOLGA7B,DHRS7B,PSMB2,SMU1,DEK,HSPA5,DNAJC5,IFI27,H2BC9,EIF2D,PDLIM4,ALKBH5,JPT1,PIWIL3,CPTP,RBPJ,PITPNB,RPL7,SRP54,TNF,RGS2,PAXX,MRPL23,GNL1,SST,RBM15B,HBB,OAS1,PEX3,HNRNPH3,SLC25A31,TMEM203,CHDH,GAL3ST1,BCS1L,WWP1,CBLN3,IRF6,FKBP10,BICD2,TYROBP,AZIN2,DECR2,FTH1,SP1,RANGRF,TNFAIP8L2,BACH1,MAFG,RIOX2,ZDHHC17,ST6GAL1,DENND6B,GKAP1,FAM50B,RNASEL,INSM2,EEIG1,SCG5,RUNX1,DNAJB2,FGF23,IDH3B,RNASET2,ATP1A3,PSMB10,NGDN,TGFB2,IRF2BPL,GALNT17,CYB5B,YWHAB,ERH,TAF11,RAG1,TRAPPC4,TMEM50B,PIGY,VDAC1,CYP27B1,CD34,LITAF,SERPINB1,OIP5,GALNT4,POLR2G,TMED1,ZNF581,HACD3,PTGES3,TUBB4B,NCK1,HPGDS,TNFAIP1,ABCG2,MOB3B,MAPKAPK3,ATP5PO,TRIM26,TMEM208,ATP6V0E1,SLC2A3,ST6GALNAC3,TXN,TMEM127,INTS6L,COX4I2,SNRPB,JMJD8,LPAR1,PPIB,TMED5,CDC40,PPIF,CORO1C,SPOPL,FGF12,NACC2,VPS4B,FBXO25,MX2,TF,GJB2,HSD11B1,NME2,PLPP6,DAD1,ING1,SPATA4,TLR6,RAF1,MRPL52,S1PR4,ROMO1,FGFR1,SYNPR,STC1,TMEM176B,ARPP19,ZMYM3,COX8A,MRPL9,CAVIN2,GOLPH3L,PSMB5,PLEKHO2,SOX9,GOLGA7,H2BC14,PRKRA,DPAGT1,MAP2K6,HNRNPH2,USP16,GAMT,SLC13A5,B9D2,RPS28,RPL6,BRMS1,B4GALT3,BGLAP,ZFAND2A,H2BC1,RDM1,KRT7,FBXO32,ALG5,RFX4,FAF1,NF2,SPRYD4,HMX1,SLC2A8,PELP1,SH3BGRL,B3GALT1,NLRP2,HPF1,WDR3,WDR5B,TOMM22,HNRNPC,CLIC2,GLIPR2,ARL2BP,FTSJ1,MAPK4,NFKB1,GLT8D2,TGIF2,PSMB9,SYNGR4,MRPL41,TMEM91,RANBP1,DRAM1,TTR,EIF2S2,CSTF3,BMP1,SNRNP27,EMC9,DIO3,CAMSAP2,CAMP,OGDHL,TSR2,SPRED1,UBE2M,NOP53,RASL11A,SLC25A42,SLC25A27,SERPINH1,PPAN,CALR,ATF4,SDHAF4,CSE1L,BABAM1,CD1B,MKLN1,PRICKLE2,ELF1,MRPS35,NR1H2,IL6,SLC30A5,PRR19,PIP4P1,MGAT1,MLLT11,NLRP1,SDHAF2,TOM1L2,MCAT,FAM20B,POMP,SNX18,CNIH4,AP1M1,CD247,FGF7,CDKN3,APEX1,PSMD3,BUD31,MRPL20,S100A8,TAB1,METTL18,CYB5R1,NLRP6,RIT2,SNRPB2,MMAA,SPATA2,SELENOI,DIPK2A,PPIA,NEUROG2,DPEP1,MTG1,MZT2B,FAM107A,GPR85,MED21,TCEA2,FZD4,HDAC6,SLC25A11,MRPS28,TP53INP1,MX1,PACSIN3,MRPS25,DPH3,SVOP,ACTR2,RNF40,COX19,CLK4,MINDY3,HS3ST5,ADNP,ZNF576,IFT57,TICAM2,PRSS12,CHST9,ATP5MC1,SNRNP48,SPCS1,MCRIP2,SLC12A2,VAMP2,ANXA4,NAIF1,SNAPC1,TOMM40L,VDR,AQP2,RPL19,NAA16,LIAS,BSCL2,MPST,TRMT112,FA2H,IKBKB,ZNF518B,MTA3,UQCC6,OCEL1,GOLGA5,CPSF1,CAV2,GINS3,WDR83OS,PRMT2,PARP2,ZBED4,CYC1,MAP3K14,UPRT,PRRC2A,PPP1CB,STX18,TRAM1,PRDX6,GEMIN7,ZNF345,HDHD5,EEF1E1,VGLL4,NDUFAB1,LBX1,LAMP2,TMOD1,ORC5,ZNF501,CBLL1,COMMD9,RNF208,NAP1L3,CARD19,EHD1,MAGOHB,XXYLT1,TRMT10B,ZNF330,B4GAT1,SLC15A2,PLP2,ACO2,BAHD1,EXOC3,NCSTN,ENTPD4,SOD3,SH3BP4,FKBP4,UBAC2,NOS1AP,QTRT2,COX5A,TOPORS,DEFB1,PC,PRKAG1,LYPLA2,VAMP5,ABHD2,LMBRD1,COMMD8,OTUD7B,IRF8,CRAT,ABHD10,ADAMTS1,VPS16,B4GALT7,ZBTB42,SEC14L1,RAB37,LEMD3,RPL26,SSRP1,CRY1,DESI1,COX4I1,TOR1B,DDX4,OR51E2,TFIP11,EMC4,CTNND1,CNR1,FITM1,PCLAF,CFAP20,GNAI2,PLCB1,NOC4L,ELK1,FABP5,LRRC8B,B4GALT6,RBIS,JAK1,IRF2,MRPL16,MCM6,H2AC25,HERC4,MSMO1,APOBEC3G,SRSF2,GASK1B,TMEM89,SYS1,CYP39A1,APTX,MCM8,TLR7,LAMTOR2,IGFBP4,ESR2,COPS5,ST3GAL4,UNC50,ZNF287,AK2,PSRC1,TRIM32,SUMO3,CETN3,RAB29,C1GALT1C1,JUN,RPL10L,PDCD10,GAD2,ELOVL4,ARFGAP1,HSD17B10,EPOP,MINAR2,RPS13,RB1CC1,R3HDM4,KDSR,PNPLA8,LGALS3,BPIFA2,TMEM97,CPE,NDUFA1,EIF4EBP2,BRMS1L,PLA2G5,SLC41A3,GABARAP,PAK1IP1,CHCHD6,RAB6B,TMEM70,GORASP2,THRAP3,CELF6,SNX22,WTAP,SNX2,SRI,LUC7L3,SLC7A14,MRC1,UTP15,ZNHIT6,SERPINB6,HSD17B11,SNX17,LRRTM1,BUB3,ZNF704,RAB3D,TSPAN5,CFAP36,NLE1,LY96,DMAP1,SOD2,GLRX2,LSM10,MIR17,SLC8A1,STX10,DTD1,OSGEPL1,HSDL1,EIF5B,CHRM3,STX5,AKAP17A,MAIP1,LAP3,PLEKHA8,COPS2,CD1C,SIVA1,SLC37A4,TLR4,STK24,DCAF5,TNIK,CXCR1,TRAPPC14,CDK8,CRHBP,NAB1,GPRASP3,RMDN3,PPFIA3,AKT1,SLC38A9,PPP1R10,GABPA,CRYM,LPCAT3,PNMA3,POLE3,RPL12,CD4,DNAJB9,MEST,STMN2,FAM20C,ZNF862,TMBIM6,CAMLG,H1-3,GLRA1,CHMP1A,FIG4,DROSHA,CHCHD4,NUDT16,ATAD1,NIBAN2,PCGF6,CD14,ARF4,GLUL,PIWIL4,RBP2,NUDT2,ADD2,MGAT4B,GSTM2,CYP2R1,ZCCHC17,BRCA1,SNN,ZCRB1,DLG4,SPRY1,S100A10,DKK1,NDUFB4,CDKN1A,ZFAND2B,P3H1,MEAF6,RORB,MPHOSPH10,HOXC4,NBN,SLC25A1,COA5,TOMM20,AGO1,CFAP119,FIBIN,BRIX1,RPL10,TOLLIP,RPS23,SRPRA,CHGA,SNAP29,LANCL2,KCNA2,CREBZF,GADD45A,PPP2CB,SURF6,TRIM68,FHL3,PNMA2,AKIP1,CAMK2N2,PARL,DEGS1,YWHAZ,TNPO3,RAP2B,SMARCA5,TEX261,IL15,GRAP,PPP2R5A,PAK6,H2AC4,PLPPR1,PDE6D,SPACDR,PRKX,GTF2B,STX6,SDF2L1,PSMD7,PRR13,MAD2L1,SLC1A1,TICAM1,XBP1,CYTH4,DTYMK,NSA2,ABHD14B,SSPN,STX17,EXOSC8,LDHA,MDFI,LCMT1,NDC80,TMEM165,STAT2,METTL22,MAN1A2,UBA3,PFDN4,ENPEP,HDAC3,PAAF1,TBC1D10C,TLR3,RFC5,RCL1,TRAK2,DUSP9,TMEM50A,MRPL24,SNRPD3,TMEM170A,TGIF2LX,DAPK3,ENO1,STOML2,ATP5IF1,ATP2B4,PFKFB2,GRM1,CDIP1,FIS1,CRKL,NTRK2,SEC61A2,TMEM117,STAT6,HNRNPK,DYNC1I1,ACOT8,STN1,NFIL3,OTX2,TLR9,NPTX1,INTS12,HM13,TEF,LIMS2,LRWD1,PSMD12,TMEM126A,FOXA3,DCUN1D5,CRTAP,HP1BP3,ANP32B,TMX2,RPS24,ACOT13,OPRL1,CDK2AP2,OCIAD2,ORC6,TFPI,PPID,ALYREF,EXOSC4,TRIM45,SRGN,MIS12,CAMKV,TMIGD1,MRPL10,PRM1,USP46,FCAR,GTF2A2,NAP1L5,PDE4B,STPG4,CHRAC1,ANAPC4,FASLG,ANAPC2,SCAND1,ERLIN1,NKX3-2,DRGX,APOBEC3D,AP2A1,TNFAIP8L3,COPS7B,KDM1A,HADHA,RARS1,PDE8A,TOM1L1,STRADB,SCYL2,PHETA2,POLB,MTA2,SUV39H1,HECTD1,CD47,TNFRSF1B,GATD3,NAA60,RRAGB,DDX39A,CCDC69,HEXIM2,CSNK1E,RAB33A,SUGP1,PIGA,NT5C3A,PSMA3,SLC52A3,NOSIP,PROS1,RAD1,OAZ1,H2BC12,CCDC92,CATIP,ZBTB25,DHX16,NDUFAF6,CYP21A2,RPS16,SNX5,NUPR1,GLRX,SLC48A1,EHD3,EZH1,KDELR1,YIPF4,MARS1,SDC4,BLOC1S3,CYP1B1,FCHO2,CEBPE,BORCS8,GNPDA2,NCDN,RAB18,BAALC,TRIM29,CSKMT,ARMC8,SLC35E3,PRKAB1,BCL2A1,GABRA2,FANCG,LRAT,RNF121,CYB5R3,UBE2B,EPHA4,MIDEAS,CGGBP1,COA1,PRSS37,NAE1,ATP5PD,ARFIP1,AIFM1,NHERF1,NPPC,CYRIB,HSPB2,POLR3F,NUP107,PSEN1,GABARAPL2,NOL7,SF3A1,PTPN22,PSMA5,ABHD6,STX7,CSNK1G3,GH1,CCNY,ZNF655,CLEC18A,LSM6,IFIT2,TOR1AIP2,TOMM7,IGF2BP1,MRM2,RBM12,INSIG2,S100PBP,DNAJC19,TXNRD3,CKS1B,SLC30A7,TSPO2,WDR55,CDC42EP4,KICS2,KIF2A,SLC25A17,CYSTM1,B4GALT1,IRAK1BP1,CD164,SETD9,LHX2,RNF34,SOST,AKT3,GADD45B,CDC5L,TAFA1,VRTN,S100B,SSX2IP,MACROH2A2,NDUFB10,CDK5,MAGOH,TEX12,EHHADH,SLC38A7,RPL7L1,PHTF2,RBM34,RAB1B,CDK5RAP3,UFD1,VPS18,JAKMIP2,NR2E1,TMEM198,TIA1,GTF2E2,ZMAT5,YAF2,ZNF664,WEE2,POU3F4,SIAH1,MUL1,RP2,UBE2E3,CHIC2,TRAPPC2L,SNAI2,TTC1,SERPINB9,MOB4,TP53TG5,MSRB1,ZNF575,MANSC1,ATG7,SLC35A1,ZYX,CCS,SPATS2L,IL12B,GNPAT,UGDH,RNF133,UBXN10,DICER1,ATG16L1,GID8,TOMM40,DUSP3,TLCD3B,MSX1,HEXA,FEN1,AK3,MAB21L1,RBBP4,RAB3A,GRSF1,AP5M1,SERTM1,CD59,SMCHD1,MTCH2,SEPHS1,RCBTB1,DCTPP1,NDUFB8,TRAM1L1,PREB,SNIP1,TMEM115,GRAP2,RPL7A,DR1,H2AB1,CTTN,RAP2C,POU1F1,MECP2,ASPA,TM9SF4,TDRP,TIMMDC1,SPR,ENPP4,BRINP3,HCFC1R1,CEP19,ARL5B,NMRAL1,EHD4,DDX5,EIF3K,RAB9B,NUF2,CD40,ERG28,ZNF362,PTP4A3,TSPO,CFDP1,CFAP298,VPS54,SLC39A9,SDHAF1,UBA52,CHST13,DYNLL1,TASL,ARFGAP3 |
| 5.003e-15 | -32.93 | EPRS1 (glutamyl-prolyl-tRNA synthetase 1) | protein interactions | 2058 | 439 | 199 | 19454 | 5460 |
FAF1,EMC2,RPL23A,HUWE1,CCT5,COMTD1,FBP1,MIR200C,MIR15A,MIR17,TNFAIP8L1,MIR20A,ILF2,MIR106B,TFE3,HACD3,MIR25,TES,G6PD,EMC4,HDAC6,MIR34A,IDH3A,MIR205,RPA3,SOD1,MIR34C,SQSTM1,MIRLET7I,MIR7-3,FBXW7,EEF1E1,ARHGAP1,MIR1-2,STOM,RPLP0,RARS1,CTNNA1,CCNF,MIR16-1,PTEN,NDN,VIRMA,FBXO7,MIR145,CDC73,HNRNPA2B1,HSPD1,AP1M1,RAF1,B3GNT2,LGR4,ACTN4,CHMP4C,EZH2,RNF126,PHB1,MIR7-2,MIR141,MAP1LC3A,DHX15,SRSF10,PRPF19,HNRNPA1,PSMD10,AHSA1,HNRNPD,MIR1-1,CRY1,HSCB,MIR106A,G3BP2,PRDX3,EMC9,RNF7,RAN,TRMT6,RPS9,AP2M1,TUBB,TAB1,ACTB,BTG3,MAT2B,MIRLET7D,CUL3,CUL2,ACO2,KDSR,MIR98,BRCA1,MYO6,RIT1,HSP90AA1,MIR363,MIR200A,MAP1B,DHX9,MIR9-3,ERO1A,MIR16-2,MEPCE,MIRLET7C,TP53,DDX42,CD274,SYNCRIP,ARL4D,MIRLET7G,RPS16,FZR1,SPPL3,MIR429,TMPO,KARS1,ENY2,GAPDH,COPS5,H2AC4,MAP4,BAP1,MIR10B,RNF113A,DLAT,MIR29A,MARS1,HSPA5,MIR107,CAPN1,MIR34B,CFTR,CDC42,SDCBP,RPA2,HECTD1,MIR7-1,HEXIM1,MIR21,PSPC1,RPS3,KCTD9,MAT2A,UBE2H,ATP1A1,PABPC1,CCT8,MIR9-2,MIR206,SCPEP1,VDAC1,MIR155,KRAS,TOP3B,MIR222,TRAF2,SOX2,ISG15,PNMA2,PLS3,GLE1,MOB3C,MIR214,MIR9-1,TCP1,SUMO2,HNRNPL,CCT7,RPL6,WWP2,MIR143,LAMP2,GSTM3,DDRGK1,MIR29C,XPO1,AGR2,MIR31,MIR140,MIR221,RFC4,DDX5,HSPA8,SF3B1,HDAC5,EEF1G,STAU1,UFL1,BET1,PIH1D1,DLST,LMBR1L,MIRLET7B,MATR3,PTPRZ1,ESR2,HNRNPAB,MYC,HMGCS1,FBXW11 |
| 5.282e-15 | -32.87 | TRA2B (transformer 2 beta homolog) | protein interactions | 6434 | 368 | 173 | 19454 | 5460 |
SEPTIN7,MRPL49,ILF2,MIR20A,MIR17,MIR15A,MIR200C,MAP1LC3B,HINFP,ZBTB2,MRPL50,THOC1,TOP1,PRNP,MIR25,MIR106B,MIR34A,BRD3,GRSF1,NHP2,HMGB1,MIR7-3,FBXW7,MIR34C,CLK1,MIRLET7I,MIR205,PRIM2,RPA3,MTRES1,ZNF574,GRM2,LMNA,DCTN4,RBMS2,MIR1-2,SF3A1,MAGOHB,NDN,CMBL,EIF4A3,MIR16-1,CCNF,PAIP2,MIR145,IVNS1ABP,PPP1CC,SSRP1,SRSF4,G3BP1,SRSF8,SRSF7,HNRNPA2B1,CHMP4C,SKA3,EZH2,FAF2,SRSF10,MIR141,MIR7-2,RB1CC1,MIR1-1,VPS4A,MRPL18,TRA2A,HNRNPA1,MARCHF5,MIR106A,G3BP2,NKAPD1,LUM,MFAP1,MED23,RND2,MTX2,TNPO3,MIRLET7D,SNRPD2,RAN,CPSF1,MIR363,MYO6,YWHAZ,BRCA1,MIR98,CUL2,CUL3,MIR16-2,MIRLET7C,MEPCE,MIR9-3,MIR200A,SNIP1,NUPR1,GFM2,TFRC,CENPM,TP53,MIR429,MIRLET7G,FZR1,RPS16,CAND1,CDK6,CHCHD1,SNRNP70,COPS5,DPP4,MIR107,MIR29A,RNF113A,BANF1,MIR10B,BAP1,MIR7-1,TFIP11,MIR21,MIR34B,SRPK2,EIF4H,PSPC1,UBE2H,ELAVL2,PTTG1,PDCD4,RC3H2,MIR155,H1-6,EWSR1,MIR206,MIR9-2,PABPC1,RHOBTB1,ZRANB2,RAB4A,MIR222,SOX2,ANAPC13,MED9,MIR9-1,HNRNPL,MIR214,EED,SRSF1,MIR140,MAGOH,MIR221,POU5F1,MIR31,DDRGK1,YWHAG,MIR29C,MIR143,SAP18,TRA2B,SRSF2,UFL1,EP300,SF3B1,HSPA8,NGRN,SNRPA,DDX39B,ELK4,PABPC5,APEX1,ESR2,MIRLET7B,SF3B4,SNRPB,BTF3,HNRNPC,MYC |
| 5.361e-15 | -32.86 | transferase complex | cellular component | GO:1990234 | 848 | 350 | 19108 | 5553 |
ANAPC13,CSNK2A1,ORMDL1,TBK1,FBXO11,GTF2H2,MED27,FBXO8,SNRPD2,UBE2D3,MORF4L1,DCAF8L2,ZER1,RING1,TNFAIP1,METTL14,MEAF6,KBTBD6,PIK3CG,CDC16,POLR2G,RNF14,SGF29,CDKN1A,SPOP,SPSB1,STK11,ANAPC11,GTF2B,TAF9,RNF8,AZI2,DAD1,PHF1,PRKACB,TUSC3,TAF10,DPY30,FBXO25,CACYBP,CCNI,SPOPL,OST4,MED30,BECN1,TAF2,SNRPB,CDC73,TERT,ACTL9,SPSB3,MED17,KLHL3,SNRPE,SPTSSA,POLE3,ATG101,UBE2V1,CDK8,ELOC,TCEA1,POLR2L,WWP1,PIGC,POLR3H,ANAPC15,FBXO42,PIK3R2,PARD6A,DCAF5,RUVBL2,KLHL25,RBM15B,VPS72,SYVN1,PHKG1,VAC14,MNAT1,RANBP10,PGGT1B,ASB1,BRCA1,ATG3,PIGY,ERH,POLE4,CDC26,TAF11,NSMCE3,CCND3,PCGF6,UBE2A,ACTL6B,DCUN1D3,KLHL24,SESN2,EED,NAA50,SOCS2,CDK1,FZR1,RABGGTB,SKIC8,TRIM37,GTF2H4,RNF7,FBXL3,CREBBP,PRPF31,CUL3,APPBP2,FBXL19,COP1,MKLN1,WDR77,TBC1D5,RMND5B,KCTD17,ING5,FBXL14,MAX,PRMT5,CDK5R1,TAF7,GNPTG,FNTB,KLHL22,CCND1,WWP2,POLR2I,CBX5,POLR2D,PCGF2,E2F6,PIK3R1,PIK3R3,RBBP7,ENY2,RCHY1,STRADB,PHC1,UBE2I,BCCIP,C9orf72,TENT2,PHKB,ANAPC4,MCM3,ANAPC2,UBE2V2,POLR1D,PRPSAP1,GTF2A2,GTF2F2,CHRAC1,TADA1,FBXO32,PAAF1,MAT2A,PRDM4,GOLGA7,KLHL15,CDK4,ANKIB1,DPM2,NUS1,SLA2,KLHL7,PDSS2,DCUN1D5,THG1L,POLD2,GPR37,CDK9,CSNK2B,FEM1B,POLR2F,EP300,FBXO7,UBE2N,YPEL5,WDR5B,FBXO31,CCNH,VIRMA,PELP1,CXXC1,SNRPD3,BRAP,CBLL1,FBXW7,CDKN1B,NAA30,ENC1,NAA35,CCNY,JADE1,TMEM183A,KCTD10,SOCS3,SUPT7L,SPTSSB,DCAF4,NAA15,IGF1R,PRKAG1,OS9,CCNQ,QTRT2,TOPORS,FEM1C,ACVR1,ANAPC16,TANK,GTF2A1,DET1,NAA11,UBE2L3,UBE2S,CKS1B,RNF11,TERC,KANSL3,HCFC2,FBXO44,SNRPD1,FAM8A1,POLR1H,FBXL4,CDK12,MAVS,MSL2,EZH1,TRAF2,PAGR1,RNF40,PCGF3,TADA3,PYCARD,FBXO3,ACVR1B,CCNB1,PHKA1,RPN1,PIGA,TRIM21,MED21,DTL,POLR3F,TGFBR2,IKBKB,TAF5L,NAA16,OTULIN,TRAF7,SOCS5,UBE2B,FBXO9,ARMC8,MED10,AKAP14,SUPT3H,PRKAB1,UBE2D1,MED11,ACTL6A,CNPPD1,RNF20,DCAF11,PRIM2,PRPS1,CCNA2,CBX7,WDR82,RNF144B,CDC20,WTAP,FBXW4,DR1,GTF2F1,STUB1,CAB39,FBXL7,FBXW11,CDK7,RUVBL1,PIK3CA,POLR2C,ORMDL3,SF3B5,RB1,CDKN2D,EPOP,RB1CC1,POLR1B,PCMTD1,DYRK2,SNRPG,CCNF,TRMT61A,TRMT6,ACVR1C,MAD2L2,PCNA,STT3A,GOLGA7B,POLR3B,EZH2,DCAF16,KLHL9,CDC23,DMAP1,XRCC5,INO80C,CAND1,DCAF4L2,GID4,CUL2,ERCC3,GTF2H5,ELOVL6,NRBF2,GTF2E1,SOCS4,FEM1A,DAPK1,GTF2E2,CKS2,ACTB,POLR2B,CDK6,RBCK1,CRBN,CDK5,HSD17B10,POLR3GL,ILVBL,MAEA,POLD4,RBBP4,ATG16L1,GID8,KLHL12,SKP1,CISH,DCAF12L2,MED31,DCUN1D1,POLA2,MAT2B |
| 5.474e-15 | -32.84 | EMC1 (ER membrane protein complex subunit 1) | protein interactions | 23065 | 409 | 188 | 19454 | 5460 |
RND3,PTRH2,ISG15,DNAJC25,RANBP1,SUPT5H,OR4N2,VDAC1,KRAS,CHCHD2,SEC11A,NDUFB5,YWHAB,AK2,XPO1,YWHAH,CCT7,RHOH,GYS1,UBAC2,EDEM3,GOSR2,RER1,EMC1,NDUFS2,AKAP1,RAB5A,EP300,SF3B1,TMEM106B,ZMPSTE24,MDH1,FIS1,ICAM1,S100A11,PSMD1,TMED5,ATP6AP2,ESR2,NDFIP1,TAGLN2,ATP5F1B,LMBR1L,VDAC2,GNAI3,SLC25A24,DISC1,TFRC,FAM162A,TP53,FKBP8,CSE1L,L1CAM,ATP2B4,SLC25A11,SNIP1,GAPDH,KLHL22,SCGB1D1,COPS5,ADIPOR2,PGAM1,KARS1,DPP4,LMAN1,SPPL3,TMED9,DNAJC1,RAC2,COX4I1,RPL32,SDHB,CD274,STT3A,CYC1,RPA2,CDC42,GTF2H4,HSPA5,OGDHL,DERL1,PRDX6,CALU,ATP1A1,DNAJC10,ATP1B3,SUB1,RAB2A,RALA,PSMC5,UQCRC2,PLD3,CYB5B,BZW2,GDI2,RPN1,ERLIN2,CYB5R1,GFPT1,FAF2,EMC10,ANP32B,FLOT1,ETFA,EMC8,SLC25A5,RB1CC1,RHOG,EMC6,STOML2,NUP35,TMEM237,ERLIN1,DNAJB9,XPO5,PHB1,FOLR1,FKBP10,EMC9,ARMCX3,MED23,SCGB1C1,PRDX3,OTULINL,RND2,DNAJC22,PYGB,ATAD1,HSCB,ATP2C1,DNAJC3,SCFD1,TMED4,CUL3,SPCS1,MRPL23,SEC61B,RMDN3,PIGK,CYB5R3,ILF2,HSPA13,PGM1,MAP1LC3B,CCDC47,GALNT2,PSEN1,PDE2A,DNAJC30,HUWE1,EMC2,SNAP23,SFXN1,NSDHL,PPP1R12A,ESYT1,POR,HM13,SLC25A46,EMC4,CALR,CAV1,SLC25A12,TOMM70,EXTL2,DERL2,PTPN1,STOM,LMNA,ST7,UQCRC1,SF3A1,PCK2,RTN4,SPCS2,MME,RPA3,ATP5F1A,RALB,SEC63,VIRMA,SLC25A4,RHOJ,RAB14,COPE,LDHA,GANAB,ENO1 |
| 5.815e-15 | -32.78 | SOX2 (SRY-box transcription factor 2) | protein interactions | 6657 | 1342 | 503 | 19454 | 5460 |
BRMS1L,CAND1,FZR1,MTAP,ALYREF,MRPS9,SSBP1,AKAP8L,LSM3,SMCHD1,RPL24,SEPHS1,MEPCE,HNRNPK,PSMA5,DHX9,MAP1B,GNAI3,CAPN2,RPSA,IMP3,IDE,IRF2BP1,MACROH2A1,CYTH1,PHAX,SRP54,RBM7,IGF2BP1,ENDOD1,MECP2,GLOD4,MRPS16,ARHGAP21,CFL1,ATF4,SLC25A1,AKT1,SMARCA5,CLU,UGP2,HDAC3,RPS15,WDR3,LSM12,PGK1,RPL27,TFIP11,AGO1,HSP90AB1,CCT7,GLRX,TRMT61A,MITF,SUMO2,SNRPA1,HNRNPL,WDR82,ANXA4,RBM5,FUBP3,SIN3A,ARMC8,POU5F1,DDX1,CDC23,CTNNB1,TOR4A,XPO1,DNTTIP1,YWHAG,CDC26,RPL6,WWP2,BAZ1B,LAMP2,DDX50,IMPA2,RPS4X,RUVBL1,HNRNPF,PSMA1,BCL9,MYO1B,EWSR1,LSM14A,BCL7B,SMARCB1,PLS3,EEF2,TUBA1A,TRMT1L,TAGLN2,MATR3,ZMYM2,MIDEAS,DLST,ATXN1L,MDH1,COP1,CKB,CCT2,BAG3,SNRPB,SFN,HNRNPC,LDHB,PSMA4,EEF1G,TRA2B,MED13L,DDX5,SPECC1L,CCDC9B,PEBP1,CSNK1A1,AKR1A1,NUFIP2,PPT1,MRPL12,GPC4,PSMB3,DUSP14,MSMO1,MRPL24,MRPS23,NCBP2,SEMA3C,RPL35A,EFCAB7,PSMB1,MYBL2,KRR1,RPL12,TFE3,FOXP1,PRICKLE2,SPATS2L,GRSF1,FARSA,NOC4L,NKRF,RAB1A,PPP1R12A,SERPINA1,NDUFS3,UBE2V1,GBE1,CCT5,CMPK1,GNAI2,FERMT2,TMOD3,PNP,COPE,MSN,RPS12,ENO1,EIF2AK2,TUBA1B,CTTN,CDC73,YPEL5,RPL26,ZNF687,LSM8,BRIX1,MEF2A,PIAS1,NF2,TTR,PPIH,RTN4,GLIPR1,GID8,RPA3,RARS1,MEST,STOM,PICALM,ST7,ARHGAP1,DHX15,PPIA,SNX18,ATP6V1A,KRT8,MRTO4,PSMB4,RPL8,MRPS26,ZCCHC9,BCL7C,PDIA3,SSRP1,FLOT1,FOXP4,RAD21,AHCYL1,PSMD12,RPS27A,BAG2,SCD5,MKLN1,HNRNPA2B1,MAEA,HSPD1,SCYL2,SLC25A5,SART3,POLR2C,RPS11,GDI2,RPN1,JUN,ACTN4,ANP32A,MACO1,PRDX2,MRPL23,SNRPD2,ILK,LSM14B,SETD7,HSP90AA1,SCFD1,YWHAZ,CAPG,SMARCE1,PKP4,RAB11A,AZGP1,NOP53,YTHDF1,UCHL3,EMG1,EXD2,ANXA7,PRSS23,ELOVL1,MFAP1,CRYAB,VAPB,DET1,SOX21,ACTL6A,SLAIN2,TMPO,RPS16,PREP,EEF1B2,USP15,CDK12,TUBG1,KLHL22,PRSS12,ZNF24,KARS1,CMSS1,CAPZA1,TOLLIP,MSANTD4,IDH1,RPL3,MRPS18B,ABCE1,SLC25A11,SOX14,TAF2,PSMC3,RBM34,CRABP2,ACTR1A,CDK4,SRPK2,MRPS28,PSMC5,QSER1,LIG3,PSMA6,RPS3,SERPINB1,ANAPC4,LSM6,CHPF,RPS17,TIA1,MED22,ABCC2,MRPL41,KDM1A,LCP1,PRDX6,HNRNPH2,TWNK,BANF1,CHRNB2,UBE2M,GSTP1,UTP15,ZNF267,RPA2,SDCBP,PLP2,SUMO1,CAPN1,SPTBN1,HMG20A,TCP1,LYAR,FAM98A,MAGED2,FABP5,SERPINC1,HSPB1,FKBP4,DCAF5,UTP6,MRPL9,POLDIP3,PAX6,MAGEC2,SATB1,ZNF609,RTCB,GALC,RUVBL2,CCT8,GNAZ,RPL18,MTA2,KIF2A,SOX2,SUPT5H,KCNH8,TRIM29,ATP5F1B,ANAPC2,EFHD2,DNAJB6,FTSJ3,CHTOP,H1-10,CCDC85B,MLF2,RPL39,LDB1,EPS8,GFUS,COPS7A,MRPS7,RANBP10,ZBTB5,STAU1,OXCT1,SOX3,HNRNPA0,EP300,RAB5A,P4HA2,XRCC5,PYM1,RFC4,CTBP1,PAK2,CD59,ZNF362,RPL27A,SLC25A12,G6PD,TOP1,KCTD15,SEC23A,AIFM1,SRP14,ETV6,SSX2IP,PSMD7,SLC2A1,TLE1,CALR,ARF4,CTNND1,OLA1,RPS13,HSPE1,TOM1,TF,BACH1,THRAP3,LSM4,SEMG2,SNAP23,HSD17B10,SEPTIN7,ZNF787,SLC25A10,EHD4,MRPL49,RAD23B,SRP72,ILF2,JCHAIN,DMAP1,RPL15,ING1,DDX39A,YTHDF2,MRPL11,MTA3,DDAH2,TECR,TENT2,RPL13A,YES1,LDHA,TRIM24,RPS20,ACAT1,PRKRA,EIF4A3,PELP1,NAPA,ATP5F1A,RUNX1,POLDIP2,SS18,NHP2,MBD3,RPL4,GTF2I,EIF5B,DGCR8,ARPC2,SQSTM1,PRPF4,FADS2,PNO1,H2AC7,LSM2,CDK1,MRPS34,RBMS2,CNP,SIPA1L1,TPT1,CPSF4,RPS14,RBFOX2,CCAR2,NOP58,CYB5A,GJA1,XPO5,MYEF2,SP2,NQO1,CD58,HBA1,MRPS35,PRDX1,PSMD3,PRPF19,PGAP3,RFC2,ANP32B,SRSF4,TRIM26,RBBP7,G3BP1,PPAN,MEF2C,SSBP3,ENPP4,VPS33A,CCS,FEN1,RPL19,PARL,TNPO3,SNRPB2,RBBP4,RPL7L1,AP2M1,RAN,LMNB1,GALE,GGH,OTUD7B,RFC5,NOP16,HNF1B,G3BP2,NT5C3A,NUBP2,HADHA,RMND5B,UPF3B,ATP5MK,LUM,ADNP,RAB6A,MTX2 |
| 5.817e-15 | -32.78 | AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2) | protein interactions | 7965 | 434 | 197 | 19454 | 5460 |
STUB1,CCNF,ENO1,RTRAF,RPS20,RAB14,VIRMA,CSK,CIAO1,NTAQ1,ATP5F1A,TUFM,USP14,GMPS,RPA3,MIR205,MIRLET7I,MIR34C,MTDH,HMGB1,ATG16L1,ARHGAP1,EEF1E1,UQCRC1,CDK1,HSP90B1,RARS1,RPLP0,AIFM1,PSMB1,MIR25,PLEKHF2,DBT,HDAC6,DNAJC7,MIR34A,SFXN1,SEPTIN7,FARSA,CTNND1,CCT5,GBE1,MIR200C,MIR15A,MIR20A,ILF2,RAN,RPS9,PRDX2,SIAH1,ACTB,TSN,DSN1,CUL2,CUL3,MCM3,YWHAZ,BRCA1,EXOC8,HSP90AA1,PFDN6,NMRAL1,BIRC2,MIR106A,PRDX3,TIMM13,PPP1CB,PHB1,MIR7-2,CCAR2,PPIA,DHX15,PDIA3,PRDX1,TEX12,HNRNPA1,CSTA,TRAF6,NAB2,HSPD1,HNRNPA2B1,SRSF7,FHL3,UBE3A,AP1M1,NAA15,RAF1,NUP153,PPP2R1A,RPS3,UQCRC2,PSMC5,BUB3,MAT2A,CFL1,GORASP2,ATP1A1,UBE2H,BAP1,HNRNPH2,RNF113A,GRPEL1,HSPA5,MIR107,MIR29A,MARS1,MIR34B,CAPN1,CD2AP,SDCBP,RPA2,FGFR1,GSTP1,MIR21,TFIP11,MIR7-1,SDHB,ATP8A1,MTAP,FZR1,CAND1,MIR429,KARS1,GAPDH,H2AC4,RPS2,MAP4,ATP6V1D,MAP1B,PSME1,HNRNPK,KPNA2,CSE1L,MIRLET7C,CAPZA1,RPSA,TP53,ACTR1A,DISC1,VDAC2,MIRLET7B,MATR3,PSMD4,ATP5F1B,TAGLN2,MYC,LMO2,PSMA4,EPS8,PSMD1,BAG3,BEX3,CCT2,PRSS1,SLU7,HSPA8,DDX5,EP300,HNRNPA0,UFL1,EEF1G,RPL27A,PSMB3,TANK,LMO3,GSTM2,KLC2,PIH1D1,GYS1,WDR82,MIR214,HNRNPL,TCP1,CCT7,HSP90AB1,GSTM3,WWP2,XPO1,DDRGK1,AK2,MIR221,CCT8,RUVBL2,PDIA6,PSMA1,KRAS,HNRNPF,RUVBL1,RPS4X,NETO2,RANBP1,TUBA1A,TRAF2,MIR222,EEF2,PNMA2,RAB4A |
| 6.631e-15 | -32.65 | RAB1A (RAB1A, member RAS oncogene family) | protein interactions | 5861 | 440 | 199 | 19454 | 5460 |
TFCP2,CAPZA2,UBL4A,MTCH2,RAP1A,CAPZA1,ATP1A2,RAB3B,PSME1,MAP4,TRAPPC2L,USP2,ILVBL,CAND1,MIF,MTAP,RAC2,SYNCRIP,HEXIM1,VPS54,UBE2M,CYC1,RPA2,LDHAL6B,FGFR1,CDC42,EIF4E,TOMM20,HSPA5,UBE2K,RAB9A,BAP1,IGF2BP1,ATP1A1,SPOP,ATP1B3,RAP2C,TLR9,MTPN,GORASP2,RAB2A,PTPN11,TXNDC12,ADRM1,CREB1,UQCRC2,TUBB4B,RAB4A,PDHA1,SOX2,EEF2,RANBP1,RAB18,KRAS,VDAC1,RABGGTB,NDUFB8,AGR2,LAMP2,GSTM3,RAB5C,HSP90AB1,ADCK1,RAB1B,RHOH,EED,RAB31,RAB35,CTBP1,YIPF5,PTAR1,RER1,PHB2,COX17,HSPA8,RAB5A,EP300,AKAP1,CCT2,LAMTOR1,PSMD14,ATG3,BAG3,SLC30A5,MYC,RUSC2,LDHB,RABIF,ESR2,ATP5F1B,VDAC2,LMBR1L,DLST,SLC25A20,TRAPPC13,MAP1LC3B,EEF1A1,CCDC47,TRIM6,SOCS2,GALNT2,RNF115,GNG5,TLR4,SFXN1,SSX2IP,DNAJC7,PSMD7,LAMP3,ATP1B1,ATP5PD,TOMM70,G6PD,ARF6,AIFM1,HRAS,RARS1,LMNA,GOLGA5,SLC35E1,FUT8,FLCN,SQSTM1,RTN4,RPA3,RHOU,CDC73,ATP5F1A,GMPS,TUFM,TECR,UQCRQ,VIRMA,LDHA,PNP,RAB14,TXN,RHOJ,MSN,VAMP3,STX12,SART3,EZH2,RPN1,GDI2,RAB6B,PPP2R1A,CYB5R1,RAF1,B3GNT2,PSMD12,TMED7,SSRP1,ARL5B,G3BP1,ETFA,TRIM37,SLC39A7,HSPD1,AHSA1,HNRNPD,RB1CC1,BCL2L1,RHOG,ATG7,HNRNPA1,PDIA3,STOML2,NDUFS8,CACYBP,ZNF593,RAB11B,OCRL,ATP6V1A,PHB1,OCIAD2,TBC1D17,SLC25A3,PPP1CB,RND2,PRDX3,RAB6A,CDKN1A,PXMP2,STX7,RABAC1,HADHA,SCFD1,ATP1A3,RHOB,TOMM40,KDSR,TMED4,TM9SF4,RAB11A,ACTB,ARF1,CYB5R3,ENO2 |
| 6.722e-15 | -32.63 | HSP90AB1 (heat shock protein 90 alpha family class B member 1) | protein interactions | 3326 | 767 | 313 | 19454 | 5460 |
TRIM6,CCT5,TBK1,FBP1,MAP1LC3B,TAF1D,STARD13,RAD23B,TRAPPC13,RAB1A,FAF1,PPP1R12A,IGF1R,HSPE1,WASL,TTC4,HUWE1,PTGES3,CDC37L1,EMC4,NFKB1,CALR,HDAC6,CRBN,SLC2A1,STYK1,FGR,DNAJC7,EEF1AKMT3,TES,DERL2,DCUN1D1,MDM2,POLE3,CDK9,UBA52,ARHGAP1,ATG16L1,GABARAPL2,CDK7,GRM2,METTL14,JUP,PTP4A2,MET,RPLP0,CYP17A1,RPA3,SOD1,INPPL1,SQSTM1,SYVN1,RPL4,GTF2I,NPM3,CSK,TUFM,AR,ATP5F1A,IVNS1ABP,TXNIP,CHORDC1,MAPRE1,NCKIPSD,CDC73,STK11,ENO1,CCNF,STUB1,PTEN,UBASH3B,GSK3A,YES1,LDHA,NDN,COPE,TXN,GNAI2,VIRMA,TXNRD1,RAF1,B3GNT2,GTF2E2,GABARAPL1,ACTN4,NME1,EXOSC3,CHMP4C,PPID,EZH2,BCKDK,HSPD1,MAP3K11,TESK2,UBE3A,CDK20,TRIM37,COPS4,RAD21,PSMD12,MCM6,MARCHF5,TRIM8,STOML2,PDIA3,DYRK1B,MAP3K14,ATG7,HNRNPA1,PPM1B,DICER1,HNRNPD,AHSA1,HAX1,RB1CC1,PHB1,PSMB5,FOLR1,WDR6,COPS2,HYPK,CCAR2,RPL7,SPTAN1,COPS7B,SRSF10,CACYBP,DET1,MYL6,PSMA3,HADHA,UNC45A,FBXL4,CUL3,CUL2,GALE,MAP3K21,DCAF4,BRCA1,YWHAZ,PSKH1,ILK,HSP90AA1,PFDN2,ARF1,SNRPD1,TUBB,DYNLL1,B4GALT3,TAB1,LGALS3,ACTB,FCHSD2,JAK2,CLIC4,BTG3,MTCH2,INSIG2,RPSA,TP53,CDK4,UBL4A,ATP5PB,TFCP2,SBK2,PSMC3,TNNI3K,MAP1B,RPL3,ERO1A,KPNA2,NUP107,FKBP8,RPL17,MEPCE,ADIPOR2,GAPDH,TPM3,CSNK2A1,COPS5,TRAPPC2L,SHC1,TUBG1,USP15,RPL10A,IGFBP4,RPS2,RPL32,AIP,SYNCRIP,ITK,CD4,CDK6,CAND1,RPS16,FZR1,CDC5L,EPHB6,CFTR,SMYD3,GABRA1,NEK2,AGO1,POLR1D,FGFR1,RPA2,HECTD1,HEXIM1,UBE2M,PML,BAP1,DDX46,RNF113A,PGK1,CRYL1,HSPA5,METTL22,RPL7A,PTPN11,AKT1,SLC25A1,RAB2A,AKT3,SLC6A4,PRKACB,CHRAC1,RC3H2,UBE2H,TSSK1B,UQCRC2,FKBPL,SGTA,B4GALT1,PRKCE,ADRM1,KCTD9,MAP3K3,SRC,ACP2,MYG1,EEF2,MSX2,SOX2,TRAF2,TUBA1A,ISG15,TUBB4B,RPS23,TAF10,MOB3C,RUVBL2,RPAP3,TRIM21,CDK5,PSMA2,KRAS,RPS4X,CCAR1,DIRAS2,WWP2,RPL6,MAPK4,PRKX,CTNNB1,DDRGK1,YWHAH,YWHAG,XPO1,FKBP4,AGR2,IKBKB,HSPB1,YWHAB,MGMT,MAGED2,EED,TCP1,SUMO2,DYNC1I2,PGR,ADCK1,TTC9C,HSP90AB1,MAP2K1,PPT1,PIH1D1,CSNK1A1,DDX39B,BMPR1A,YAF2,HSPA8,HDAC5,UFL1,UBE2D3,COPS7A,MYC,BAG3,BTF3,PSMD1,RPS6KA4,PSMD14,RBBP8,CCT2,DNAJB6,MDH1,RPS26,NFKBIB,VDAC2,LMBR1L,PSMD4,ATP5F1B,STAT1,PPP5C |
| 6.867e-15 | -32.61 | RAS | smart domains | SM00173 | 134 | 78 | 9717 | 2575 |
RAB3B,RHOG,RAB9A,RAB5A,RAP1B,RAB35,RHOB,DNAJC27,NKIRAS1,RAB11B,RAB8B,ARL4A,HRAS,RASD1,RAB19,RAB32,RAB3C,RAB28,RHOBTB1,RHOH,RABL2B,NKIRAS2,DIRAS2,RAB5C,RAB33A,CDC42,RAB22A,RAP1A,RAB3D,RAP2C,RAB6A,RIT2,RAB29,RAB4A,RAB27A,RND3,RAC2,DIRAS3,RIT1,RAB3A,RRAS2,RAB6B,RAB14,RAB37,ARL4D,ERAS,AGAP1,RALB,RHOU,RAB13,RAN,RAP2B,RHOJ,RAB39B,RAB1A,RND2,MRAS,DIRAS1,RASL10B,RAB9B,RAB40AL,RAB31,RALA,RAB2A,RASL11A,RAB30,RHEB,RASL10A,RERG,RASL12,RAP2A,RAB33B,RAB18,KRAS,RAB11A,RAB23,AGAP2,RAB1B |
| 6.943e-15 | -32.60 | SF3B2 (splicing factor 3b subunit 2) | protein interactions | 10992 | 496 | 219 | 19454 | 5460 |
PABPC5,MTF1,CNDP2,SNRPA,DDX39B,SLU7,HDAC5,HSPA8,SF3B1,EP300,TRA2B,FXR2,SRSF2,UFL1,STAU1,MYC,HNRNPC,TTC33,SNRPB,BAG3,FBXW11,H1-1,MIRLET7B,SF3B4,MATR3,RANBP1,H1-3,MIR222,RPS7,PLS3,HDAC11,SMNDC1,MIR9-2,EWSR1,MIR206,ACTR1B,H1-6,KRAS,HNRNPF,MIR155,ZCCHC10,MIR143,WWP2,MIR29C,DDRGK1,MIR31,MIR221,MAGOH,SRSF1,MIR214,RPS10,SNRPA1,SNRPD3,MIR9-1,COMMD6,SUMO2,HSP90AB1,MIR34B,CFTR,FGF13,RPA2,TFIP11,MIR21,HEXIM1,MIR7-1,BAP1,DDX46,MIR10B,RNF113A,KDM1A,MIR107,HSPA5,MIR29A,SUGP1,PTPN11,RPL7A,RC3H2,RBM7,UBE2H,PSPC1,SF3B6,CSNK2B,SMURF1,IDE,RRM1,RPSA,TP53,H2AX,DDX42,MIR200A,SNIP1,RPL3,H3C1,KPNA2,MIRLET7C,MEPCE,MIR16-2,RBM17,COPS5,CSNK2A1,SNRNP70,H2AC4,RPS2,LSM3,NOL12,TMOD2,ITGA6,PREP,FZR1,TMED9,RPS16,CAND1,MIRLET7G,RBM42,MIR429,CDC5L,SURF6,ALKBH3,H1-5,TIMM13,PRDX3,MIR106A,CUL3,MIR98,MCM4,YWHAZ,ZCRB1,BRCA1,MIR363,RIT1,SNRPD1,SNRPD2,RPL35,MIRLET7D,SNRPB2,RPL19,RAF1,EZH2,SF3B5,SNRPE,HSPD1,HNRNPA2B1,DHX16,SRSF4,MCM6,PRPF19,FRA10AC1,HNRNPA1,SKIC8,MIR1-1,MIR7-2,PHB1,MIR141,DHX15,SF3A1,SNRPN,MIR1-2,TOX4,DCTN4,METTL14,LSM2,RPA3,SIRT7,MIR205,MIRLET7I,TCEA1,MIR34C,SMC4,FBXW7,MIR7-3,UTP23,RPL26,RUNX1,AR,DNAJC8,MIR145,MIR16-1,CCNF,CTTN,EIF4A3,TRIM24,COPE,TXN,TMOD3,NDN,YES1,VIRMA,FBP1,CD2BP2,MIR200C,MIR15A,EEF1A1,MIR20A,MIR17,PPP4C,ILF2,CASK,RAB1A,HAPSTR1,RPL23A,EMC2,CTNNBL1,THRAP3,VTA1,SNRPG,MSH6,RIGI,MIR34A,TOPBP1,SMAD3,MIR106B,KRR1,RCHY1,PRR3,MIR25,THOC1,CDK9,ZBTB2,CWC15 |
| 7.156e-15 | -32.57 | RPS23 (ribosomal protein S23) | protein interactions | 6228 | 342 | 163 | 19454 | 5460 |
RPS24,TMEM147,MRPS11,RPL31,SLC25A5,RPS4X,UBE2A,RPS27A,RPL28,TNF,EMC8,KRAS,G3BP1,RPL29,EEF2,RPS7,RAF1,B3GNT2,RPS11,RPL18,CHMP4C,EED,RPLP1,RPLP2,COPS2,RPL8,RPL9,FOLR1,PHB1,HSP90AB1,RPS10,RPL7,ATG7,XPO1,DDRGK1,WWP2,RPL6,POU5F1,AHSA1,RB1CC1,RPL23,DRG1,AGR2,ATP5IF1,PYM1,RPS28,G3BP2,UFL1,STAU1,FUNDC1,RPL27A,NOTCH2,EIF4B,PIH1D1,EMC9,MAP2K1,RPL37A,RPS9,SEC61B,FAU,RPL19,ESR2,RPL10,RPL35,BTF3,RPS29,MYC,CUL3,CUL2,RPS26,ICAM1,RPS5,RIT1,H1-1,BRCA1,ATG3,RPL3,RPL23A,MEPCE,RPS13,RPL17,RIGI,EIF3E,NEDD8,HUWE1,VRK1,EEF1A1,MAP1LC3B,RPL15,FBP1,RPSA,ILF2,NUPR1,SRP72,TFCP2,PSMB1,RPL12,SRP14,RCHY1,RPL32,ACTA2,MDM2,TMPO,RBM42,RPS16,CAND1,FZR1,SPPL3,PRNP,RPS27L,HDAC6,COPS5,CD81,ENY2,DPP4,EMC4,RPS2,RPL10A,TUBG1,RPL24,SNRNP70,RNF113A,RPA3,MME,RPL27,BAP1,SIRT7,PNO1,AATF,HSPA5,MRPL17,RPS15,FBXW7,RPL4,CFTR,RPS14,RPLP0,HEXIM1,RPA2,SAMM50,H2AC7,PRKRA,RPS20,PTEN,RPS12,CCNF,RPS3,METAP2,RPL22,NDN,RPL13A,RPL10L,RPS17,TUFM,DNAJC8,PPP1CC,USP14,AR,RPL7A,UBE2H,SPOP,EIF3G,RC3H2 |
| 7.546e-15 | -32.52 | CHMP4B (charged multivesicular body protein 4B) | protein interactions | 128866 | 703 | 291 | 19454 | 5460 |
RPL7A,SLC25A1,RAB2A,TRIM32,ARHGAP21,RPS17,CFL2,CFL1,DNAJC10,MECP2,ABCG2,OAT,TMA7,RPS3,MACROH2A1,GNAO1,CSNK2B,EIF2S2,RBMX2,CHMP5,RPL10L,SPTBN1,CFTR,CD2AP,CDC42,SAMM50,RPA2,CSNK1A1L,H2BC11,ACACA,LUC7L3,UTP15,TFIP11,NLE1,BANF1,RBM23,CORO6,RPL27,DDX46,HNRNPH2,WDR3,RPS15,MARS1,ELOC,ROGDI,RPL24,SHC1,RPL10A,RPS2,COMT,ALYREF,ACSL4,SYNCRIP,MIF,CAND1,RPS16,DKC1,TMPO,SLC38A2,TP53,RPSA,STRBP,ARPC3,NEFL,CAPZA2,TAF2,SLC25A24,GNAI3,UGCG,PALM2AKAP2,DHX9,RPL3,KPNA2,TMEM33,HNRNPK,CHMP1B,RPL17,CAPZA1,HNRNPC,MYC,SNRPB,H1-10,CCT2,DLST,IRF2,PAPSS2,BST2,FAM83B,ATP5F1B,MATR3,DES,RPL27A,CD59,TSHR,PALS2,SDC2,CSNK1A1,SPECC1L,RFC4,DDX5,HSPA8,SF3B1,STAU1,EEF1G,PHB2,FXR2,HNRNPA0,PACSIN3,SAP18,GNB4,RPL6,RAB5C,DDX50,CTNNB1,DDRGK1,PPIB,HSPB1,YWHAB,SRSF1,GNB3,CORO1C,LYAR,RPS10,HNRNPL,RAB1B,CHMP2A,HSP90AB1,RPS7,SOX2,H1-3,H2BC1,PLS3,CRKL,RPS23,RPL18,LIMD2,PABPC1,RPL31,MYO1B,RUVBL2,VDAC1,HNRNPF,KRAS,H1-6,TFG,RPS4X,DCTPP1,LRRC73,TUFM,PPP1CC,RACGAP1,KPNA6,NONO,ATP5F1A,RPL26,COL1A2,NAPA,CDC73,EIF2AK2,CTTN,UBE2I,RPS12,TRIM27,TMOD3,GNAI2,RPL22,MYL12B,RPS14,SAP30BP,CNP,STOM,CHMP1A,ZCCHC17,JUP,LMNA,MACROH2A2,RPLP0,TM9SF1,STAMBP,RPA3,SQSTM1,RPL4,GTF2I,NF2,PDHB,BRIX1,CHMP2B,ESYT1,OSBPL8,RPL12,H2AZ1,SRP14,SRPRA,PWP2,CGAS,TOP1,PPP1R18,CAV1,RPL15,MSRB3,ILF2,TCOF1,PPP1R12A,HSD17B10,RPL23A,FARSA,FN3KRP,THRAP3,PRDX4,SMN1,RIGI,EIF3E,VTA1,ARF4,RPS13,RPS29,MCM3,SMARCE1,LMNB1,ILK,RIT1,CYB5R3,ARF1,GNG12,RPS9,RPL35,DYNLL1,RBBP4,RPL19,GNB1,CHCHD3,MTX2,H1-5,MYL6,PRSS23,WBP2,NUBP2,HADHA,TXNL1,IL1B,G3BP2,SKP1,RAB3D,VPS26A,HMGA1,RAP2B,TRA2A,HNRNPA1,SKIC8,RPL23,PPP3CA,VPS4A,RPL8,FOLR1,RPLP1,ATP6V1A,BRD9,RPLP2,TSG101,RPL7,SPTAN1,INA,RAB11B,DHX15,SERINC3,SRSF10,RAF1,TPBG,RPL29,ACTN4,GFPT1,CHMP4C,CTSA,EZH2,SNRPE,RBPJ,RPS11,HNRNPA2B1,ARGLU1,MAEA,HSPD1,RPS24,BAG2,VPS26B,SRSF7,JAK1,ETFA,S100A10,G3BP1,RFC3,FLOT1 |
| 7.552e-15 | -32.52 | APOBEC3B (apolipoprotein B mRNA editing enzyme catalytic subunit 3B) | protein interactions | 9582 | 128 | 78 | 19454 | 5460 |
MIR222,APOBEC3D,CCT5,ILF2,MIR17,MIR20A,RTCB,MIR9-3,SRSF7,RPL3,CCT8,MIR9-2,MIR200A,HNRNPDL,MIR16-2,RPL17,MSL2,MIRLET7C,MIR155,G3BP1,MIR29C,HNRNPA1,WWP2,MIR143,IFI16,MIR140,MIR34A,MIR1-1,RPS2,MIR221,DNAJC7,AGR2,SNRNP70,MIR31,MIR25,MIR141,PRR3,EED,MIR7-2,CCT7,MIR429,MIRLET7G,TCP1,MIR9-1,HNRNPL,RBMS2,PPP1CB,MIR1-2,UBA52,TPT1,MIR34B,PABPC5,MIR7-1,MIR21,LARP4B,MIR34C,HNRNPH2,MIRLET7I,MIR205,MIR10B,MIR106A,MIR29A,PPP1CC,MIR98,HNRNPC,IGF2BP1,ELAVL2,MIR363,MIR145,DNAJC10,CCT2,PSMC5,MIRLET7B,MIR16-1,ESR2,POLR2B,MIRLET7D,MATR3 |
| 7.826e-15 | -32.48 | ATP6V1A (ATPase H+ transporting V1 subunit A) | protein interactions | 523 | 240 | 124 | 19454 | 5460 |
MTPN,ATP5F1A,AR,TUFM,HMOX2,RAB2A,ATP1A1,UBE2H,BICD2,UQCRC2,VAMP3,CCNF,EIF4A3,UQCRQ,SUCLG2,VIRMA,UQCRC1,CDC42,CAPN1,EEF1E1,CYC1,PTP4A2,RPA2,FGFR1,STOM,PRDX6,RAB9A,BAP1,RHOU,RPA3,SOD1,TXNDC17,PDHB,KARS1,EMC4,LAMTOR2,ATP6V1D,POR,MTAP,COMT,COX4I1,MYL12A,PRNP,URM1,IRGQ,MTCH2,NUPR1,TFRC,ACADSB,NDUFS3,ABCE1,SEPTIN7,RAB1A,FAF1,RIGI,SMN1,ATP1A2,PDE12,CSE1L,TGFBR2,HMGCS1,PCCB,CUL3,RIT1,LAMTOR1,ATP1A3,RMDN3,LMBR1L,VDAC2,UBE2S,ATP6AP2,ESR2,USP5,PRDX2,ATP5F1B,ACTB,LAMTOR3,RBBP4,CDKN1A,PRKAB1,ATP6V1C1,PIH1D1,CSNK1A1,ANXA7,ARMCX3,TXNL1,DNAJC3,ATP6V1G1,UNC45A,NDUFS2,PHB2,MCMBP,ATP6V1G2,STAU1,PDIA3,RAB5C,SLC38A7,PDCD10,CBL,AGR2,CORO1C,TLDC2,ATP6V1A,PHB1,ZNF593,EGLN3,NDUFS8,HNRNPL,KCTD10,SOX2,EEF2,RAF1,MARCKSL1,STX12,MOB3C,RPN1,EZH2,PDHA1,PRKAG1,NDUFB5,HSPD1,KRAS,XPNPEP1,VDAC1 |
| 8.118e-15 | -32.44 | RPL17 (ribosomal protein L17) | protein interactions | 6139 | 539 | 234 | 19454 | 5460 |
MEPCE,IMP4,MRPS33,RPL3,MRPS18B,MRPL52,SNIP1,GFM2,DNAJC2,TFCP2,MRPL47,TP53,RPSA,IMP3,SURF6,MALSU1,RBM42,DKC1,RPS27L,FZR1,CAND1,RPS16,RPL32,MRPS9,RPL10A,RPS2,RPL24,H2AC4,SNRNP70,TUBG1,E4F1,COPS5,CD81,ENY2,KARS1,HSPA5,MRPL40,RPS15,RNF113A,BAP1,RPL27,ZNF770,UBE2M,HEXIM1,RPA2,CFTR,SRPK2,SMURF1,RPL10L,RBMX2,SEC61A1,FGFBP1,PSPC1,RPS3,UBE2H,EXOSC1,TRIM23,RC3H2,ATP1B3,MECP2,RPL7A,RPL28,RPS4X,KRAS,PABPC1,RPL31,RPL18,RPS23,SLC1A2,MAGEB10,HSP90AB1,LYAR,RPS10,SRSF1,DRG1,MAGOH,AGR2,DDRGK1,NGDN,MRPL9,RIOX2,WWP2,RPL6,DDX50,MRPS7,STAU1,UFL1,HSPA8,RPS28,PIH1D1,MRPS18A,ADSS2,FGF17,RPL27A,DES,RPL10,MRPL13,ZNF189,NSA2,H1-1,COP1,ICAM1,RPS26,MRPS25,FTSJ3,BTF3,SFN,APOBEC3B,MYC,RPS13,MRPS18C,NOC4L,VRK1,PAK1IP1,RPL23A,MRPL51,SRP72,MRPL49,TOPORS,ILF2,LLPH,FNTB,RPL15,TAF1D,LBR,EEF1A1,FBP1,MRPS23,MRPL24,CDK9,MRPL50,RPL35A,PRR3,KRR1,ACTA2,RCHY1,ARL10,RPL12,MPHOSPH10,HDAC6,MRPL20,BRIX1,AATF,PIAS1,FBXW7,RPL4,HMGB1,MRPL17,NPM3,DGCR8,RPA3,OXSR1,ZNF574,RPLP0,RPL26L1,METTL14,ZCCHC17,CDK7,UBA52,RPS14,RPL22,RPL13A,NDN,RPS12,RPS20,PTEN,PRKRA,METAP2,EIF4A3,CCNF,DNAJC8,TUFM,USP14,PPP1CC,RPL26,FBXO7,SAR1B,RAD21,RPS27A,TNF,G3BP1,MRPS11,RPS24,SART3,RPS11,CHMP4C,EZH2,RPL29,MAK16,B3GNT2,RPL7,SPTAN1,RPLP2,RPLP1,HP1BP3,OCIAD2,PHB1,RPL9,FOLR1,RPL8,RPL23,RB1CC1,RSBN1L,MRPS26,AHSA1,ZCCHC9,MRPL18,MRPS35,G3BP2,MRPL57,NOP53,CCDC86,EMC9,NUDT3,NOTCH2,RPL19,RPL35,RPF1,RPL7L1,MRPL23,RPS9,SEC61B,RPL37A,ZNF22,RIT1,RPS5,HSP90AA1,BRCA1,ZCRB1,FYTTD1,ZNF668,MRPL16,NOP16,CUL3 |
| 8.395e-15 | -32.41 | ZNF598 (zinc finger protein 598, E3 ubiquitin ligase) | protein interactions | 90850 | 427 | 194 | 19454 | 5460 |
UBE2H,ATP1A1,BICD2,ATP1B3,EIF3G,SLC25A1,CALML5,PSMC5,PSMA6,UQCRC2,RPS3,PSPC1,SSR1,SAMM50,HBB,RPA2,CXCL8,SPTBN1,MARS1,HSPA5,STK38,KDM1A,PRDX6,RPS2,GAPDH,USP2,KARS1,LMAN1,TMPO,CAND1,RPS16,RPL32,STT3A,SYNCRIP,PSMC3,SURF4,ACTR1A,TP53,IPO8,INSIG2,MTCH2,ATP5PB,CSE1L,AKAP12,PSMA5,SLC16A1,POC1B,MAP1B,PSMD14,CCT2,RBBP8,PSMD1,PSMA4,RPL10,APEX1,PSMD6,ATP5F1B,PSMD4,PRMT5,VDAC2,LMBR1L,NUFIP2,TANK,EEF1G,STAU1,PHB2,SLC31A1,NDUFS2,FXR2,UBE2D3,LCN1,HSPA8,NT5C2,DIS3L,XPO1,LAMP2,HSP90AB1,CCT7,TCP1,RPS10,S100A8,FABP5,MTA2,TUBB4B,EEF2,TOP3B,CCAR1,RUVBL1,VDAC1,PSMA1,TRIM21,CCT8,SDHC,MAPRE1,XPOT,CDC73,TUFM,ATP5F1A,STK38L,UBE2L3,COPE,TXN,RPS20,GANAB,CMBL,ENO1,TUBA1B,CCNF,RARS1,JUP,PAK5,PSMC4,FBXW7,SMC4,CERS2,RPA3,DVL2,PSMD7,POR,MOV10,ATP5PD,EIF2B2,EIF4E2,AIFM1,SRPRA,HACD3,NDUFS3,GGCT,LBR,MAP2K3,YTHDF2,CCT5,FBP1,PRDX4,RIGI,GALNT2,EIF3E,FARSA,SEPTIN7,TCOF1,SFXN1,HSP90AA1,LMNB1,YWHAZ,RNF40,TOMM40,CUL3,TNPO3,RBBP4,TUBB,RPS9,RMDN3,CYB5R3,EIF3K,UBE2S,SLC25A3,ARCN1,VAPB,PSMB7,FOXS1,ATP5PO,NOTCH2,PGRMC1,WDR77,AZGP1,CDSN,PSMC1,ATAD1,LYZ,PPM1B,HBA1,CSTA,UBE2D1,EIF3D,PRDX1,PSMD3,PPIA,CCAR2,SPTAN1,AGK,XPO5,PHB1,PSMB4,RPL8,GDI2,RPN1,PSMD12,RBBP7,RPS24,BAG2,ZC3H7A,ZYX,HSPD1,SLC25A5 |
| 8.417e-15 | -32.41 | response to nitrogen compound | biological process | GO:1901698 | 1021 | 413 | 18204 | 5365 |
REG1A,RAP1B,CRHR1,TWIST2,FOSL2,HDAC5,PRKCB,SHC1,GNA14,KDM1A,DHX15,GAD2,OS9,CAV2,MIR200C,ATP2B4,CHRM1,TLR7,EDEM1,EIF4EBP2,RAB13,DNAJB9,UBXN10,CTNNA1,STAT2,MTARC2,SOX9,MIR20A,CPEB1,EIF2B3,SESN3,GJB2,GABRG2,AANAT,PCNA,IL1A,TMUB2,DPEP1,SLC6A3,ADTRP,SULT1A3,HCFC2,ADRB2,STAT6,CCR7,CDH13,FAM8A1,FOLR2,GSTM2,SDF2L1,DHX9,GCLC,PTPN22,COL3A1,MEF2C,STAMBPL1,CAV3,ERLIN1,MAVS,HTR1A,ACHE,CAV1,IFNB1,EGR2,MIR146A,PSEN1,CD81,ATP1A3,IDE,MYD88,BRCA1,GABRB2,IFIH1,SOCS5,HSPA5,FAF2,SOCS2,LY6H,CREB1,IGF1R,SFRP1,SOS2,EPHA4,TLR3,MIR200A,DEFB124,KCNC1,GSTM3,MIR106B,KCNB1,CDK5R1,OPRM1,CHRM5,IRF3,HSP90AA1,HTR2A,INPP5K,REN,CDK1,ATP5F1A,MRGPRX1,TYMS,CYP11B1,SLC22A12,CGAS,CITED1,RB1,OGG1,CASP4,PTGER1,RAB31,GUCY1B1,CYC1,HSP90B1,CDKN1A,FOLR1,INPPL1,VAMP2,EDEM2,FOXC2,CASTOR2,GJA1,CFTR,NEFL,PDE12,ERLEC1,PPP1R1B,HRH3,DBH,TRAF2,MIR145,TMUB1,RAF1,MUL1,ROCK2,IL10,CYP11B2,ACTB,ADIPOQ,TNF,SHMT1,AGER,HRAS,MIR98,CXCR4,FBP1,RNF5,CXCL12,CDK5,RGS2,TOP2B,GABRB3,DNAJC10,STUB1,EIF2B2,CHRNA7,EZH2,CHRNB2,EDEM3,FAF1,NCSTN,EGR1,MYRF,TRIM44,NR4A2,RNF139,SLC6A4,CCNA2,SGTA,RPL23,LIPA,SP1,UFL1,PPARG,JUP,SESN2,CHMP5,NQO1,GAB1,UFD1,TSPO,BTG2,KLHL22,CDKN1B,CDO1,HPCA,GPR173,GNAI3,HADHA,TP53,MDM2,TNFSF10,TLR4,KLF4,ZBED3,HOMER1,TOMM70,PTPN1,LARGE1,ADORA1,GHR,P2RY1,TSHR,TMEM38B,COMT,DERL1,ATF1,TUBA1A,RAMP3,SYVN1,PRKCE,CRY1,GSK3A,STAT1,PCSK9,LRP6,BCL2L1,JAK2,PPP5C,SLC8A1,TRIM24,NCOA5,CNR1,CRKL,IL2,GNAI2,SEC61B,XBP1,GRIA1,GPT,OXTR,RETN,GPX1,GH1,TNFAIP3,CTNNB1,SLC1A1,TXN,AGTRAP,MAP1B,NPR2,SLC1A2,CTSK,PIK3R3,NSG1,CALR,IGF1,NFKBIA,RNF103,EP300,RFTN2,UCP2,DDI1,DRD3,UBXN6,ITGA2,GRB10,SELENOS,RTF2,IFNA13,TLR6,AIFM1,TBC1D4,AKT1,IL1B,P2RY4,KBTBD2,ELAVL4,SLC6A1,UBE2G2,PPP3CA,CIB2,LDOC1,GUCD1,PMAIP1,CD36,WNT10B,TXNIP,EDNRA,ADSS2,PAX6,SIN3A,RIGI,CD9,DNAJB2,IFNA2,JKAMP,TNIK,PSMB2,HADH,HM13,SELENON,MGST2,JAK1,PCK2,TLR9,IFNK,PLCB1,RGS10,GNRHR2,MMP9,BGLAP,MIR107,IFNA10,GNAQ,UQCRC1,GNAO1,MIR379,IL6,CSK,AHCYL1,CHRM4,UBE3A,FCER1G,ERLIN2,DDX1,SLC2A8,DNTT,YWHAG,ACVR1C,PELI1,PPARA,FLOT1,UPRT,SLC1A3,PRNP,CA2,LDLR,FOXP3,ERRFI1,AKT2,GNA11,EIF2S1,NFKB1,CHRM3,KCNJ8,DRD1,PDE2A,NPPC,NHERF1,FOS,STAT5A,GRM2,P2RY11,CCL19,TLR2,RARRES2,CYP1B1,CD2AP,THBD,BIRC2,HNRNPD,CRHBP,TAF9,ASIC1,RAP1A,SMAD3,STC1,SLC2A1,STK11,FCGR2B,HDAC6,RALB,DERL2,TMBIM6,CD40,SYK,NLRP1,GNB1,TIMP1,SRSF4,ALPL,MECP2,PDE1B,NSMCE3,TICAM1,NFE2L2,SHOC2,FBXO44,EIF2B5,OPRK1,PQBP1,AMIGO1,MAN1A2,CCDC47,PIK3R1,PIK3R2,CAMP,TACR3,MIR143,ROCK1,PDCD4,P2RY12,GPIHBP1,ICAM1,RNF121,PIK3CA,TIAM1,F7,MIR140,PIK3CG,REG1B,INSIG2,LEP,BACE1,DAG1,SRC,CALY,GNG2,EXT1,MGARP,KCNJ11,CSH1 |
| 9.108e-15 | -32.33 | MARCKS (myristoylated alanine rich protein kinase C substrate) | protein interactions | 4082 | 588 | 251 | 19454 | 5460 |
ATP6AP2,ATP5F1B,TAX1BP1,TRIM29,FAM83B,SLC38A1,LAMTOR1,FBXW11,SLC1A3,TMEM38B,MYC,AKAP1,RAB5A,DDX39B,PEBP1,RPS28,PIH1D1,CLDN4,TOMM22,USP6NL,BET1,VAMP7,SUMO2,RHOH,STX5,RAB35,SWAP70,YWHAB,PPIB,PPFIBP1,CTNNB1,DDRGK1,LAMP2,PTDSS1,VAMP8,KRAS,RUVBL1,SLC20A2,MYO1B,EFNB1,EWSR1,TMEM87A,RND3,RPS23,SNAPIN,MSX2,CTSB,RPS3,NECTIN2,UHMK1,ATP1A1,UBE2H,CISD1,DNAJC5,GORASP2,AKT3,RAB2A,PTPN11,PGK1,ARFIP1,TEX264,BAP1,ARL15,PRKCA,LEMD3,RPA2,RPRD1B,USE1,SSR1,CDC42,CFTR,SPTBN1,LMAN1,STX6,SLC38A2,TMPO,DNAJC1,ARL6IP5,FZR1,MIF,SLC39A10,ADD1,RAC2,STT3A,ITGA6,COX4I1,CAMLG,AGPAT1,CSNK2A1,COPS5,TPM3,PGAM1,DHRS7,SLC6A8,FKBP8,KPNA2,SRPRB,RAB13,SLC16A1,STX18,PALM2AKAP2,ATP2B4,RNF8,GNAI3,EXOC3,TFRC,NHERF1,UBIAD1,SNAP29,PREB,CDK4,RAP1A,CHCHD3,MB21D2,RPS9,GPR89A,ARF1,FAM91A1,CYB5R3,SLC7A11,HSP90AA1,LMNB1,WDR20,RHOB,YWHAZ,RNF40,GGH,NIBAN2,VEZT,RAB11A,PKP4,STX7,ATP5IF1,PSMA3,VAPB,RND2,RAB6A,WDR77,NOTCH2,PGRMC1,TOR1AIP2,WDR44,OCRL,SPTAN1,MPP1,KCTD10,SNX2,WDR6,PHB1,RHOG,PPM1B,WDR11,PRDX1,PDIA3,SSRP1,RETREG1,ANP32B,AHCYL1,SCD5,SCYL2,ZYX,STX12,SNRPE,EZH2,VAMP2,STIM1,RPN1,FAF2,ANP32A,MARCKSL1,RAF1,MACO1,FERMT2,SNX3,SLC25A4,YES1,RHOJ,TRIM24,PTEN,RPS12,VAMP3,GAB1,CCNF,STUB1,CTNNA1,EPHA2,ARFGAP3,DEPDC1B,HMOX2,CDC42EP4,TMEM209,NF2,YKT6,SLC7A1,PIK3R2,PRKCB,MAVS,ITGA2,SOD1,RHOU,CDK1,JUP,HSP90B1,GOLGA5,PICALM,SLC12A2,CDK7,CNP,RABL3,EEF1E1,ARHGAP1,SEC22B,PIP5K1A,ZBTB2,CAV1,ARF6,CDCA3,PTPN1,HRAS,SRPRA,EHBP1,OSBPL8,SLC2A1,SPP1,ESYT1,HM13,LAMP3,RAB23,EI24,RELL1,TMEM199,CALR,CTNND1,RNF20,ADD2,HSPE1,SEPTIN7,HAPSTR1,SNAP23,HINT1,RAB1A,NSDHL,DLG1,SFXN1,MRPL49,EEF1A1,LBR,MTARC2,SLC29A1,RPL15,CCDC47 |
| 9.196e-15 | -32.32 | RPL35 (ribosomal protein L35) | protein interactions | 11224 | 514 | 225 | 19454 | 5460 |
H1-10,FTSJ3,MRPS25,COP1,ICAM1,RPS26,NSA2,MYC,CREBBP,SFN,BTF3,PSMB6,POLR2B,ESR2,RPL10,CMTR1,MRPL13,MRPS18A,RPL27A,TOMM22,UFL1,STAU1,MRPS7,RPS28,SF3B1,HSPA8,AGR2,DRG1,DDX50,RIOX2,WWP2,RPL6,XPO1,MRPL9,DDRGK1,RPS10,ZNF511,PDHA1,RPL18,RPS23,MAX,MSX2,RPS7,KRAS,VDAC1,RPL28,RPS4X,RPL31,CCT8,PABPC1,ATP1B3,RC3H2,UBE2H,MAT2A,RPF2,MED22,RPL7A,RPS17,MRPS21,RPL10L,SMURF1,RSL24D1,RPS3,PSPC1,SEC61A1,RPA2,SSR1,HEXIM1,KLF4,ACACA,ZNF770,GABRA1,CFTR,RPS15,H2AC13,MRPL40,MRPL41,HSPA5,MARS1,BAP1,RPL27,RNF113A,SNRNP70,RPL24,RPS2,RPL10A,ENY2,COX5A,RBM17,CD81,COPS5,API5,FZR1,CAND1,RPS16,RBM42,TMPO,DKC1,SURF6,MRPS9,RPL32,DNAJC2,RBM34,RRM1,MRPL47,RPSA,MRPS33,NEDD8,MEPCE,RPL17,MRPL52,SNIP1,RPL3,MRPS18B,BRCA1,ZCRB1,SP1,RPS5,RIT1,NOP16,CUL3,RFC5,PDE4B,MRPL16,RANBP6,LGALS3,RPF1,MED17,RPL35,RPL7L1,RPL19,RPL37A,SEC61B,RPS9,CDKN1A,NOP53,FTL,G3BP2,MRPL18,MRPS26,RPL23,MRPS35,EIF3D,RPL7,RPL9,FOLR1,RPL8,PHB1,RPLP2,HP1BP3,RPN1,EZH2,CHMP4C,RPS11,B3GNT2,MAK16,G3BP1,TRIM26,TRIM37,RPS27A,PSMD12,UBE2A,TRIP4,PRPSAP1,MRPS11,SRSF7,RPS24,MAPRE1,RPL26,PPP1CC,USP14,RPL13A,RPL22,CCNF,METAP2,PRKRA,RPS12,RPS20,MRPS34,METTL14,ZNF574,RPL26L1,RPLP0,RPS14,LIAS,UBA52,CDK7,MRPL17,FBXW7,RPL4,HMGB1,PIAS1,MRPL20,AATF,UTP23,PRIM2,RPA3,CRBN,MPHOSPH10,CLIC2,MOV10,HDAC6,APOBEC3F,RPL35A,MRPL50,AKAP17A,MRPL24,MRPS23,SRP14,RPL12,KRR1,RCHY1,SRP72,FBP1,MRPL11,FCF1,RPL15,PAK1IP1,NOC4L,VRK1,FARSA,RPS13,MRPS18C,NKRF,RPL23A |
| 9.945e-15 | -32.24 | REST (RE1 silencing transcription factor) | protein interactions | 5978 | 256 | 130 | 19454 | 5460 |
HNRNPD,MRPS26,RPL23,HMGA1,RPL6,EIF2S1,RPS10,HNRNPL,RPL7,SNRPD3,LYAR,SNRPA1,RPLP1,RPLP2,RPL8,SIN3A,RPL9,SRSF1,RPS11,RPS23,SNRPE,RPL18,EZH2,TUBB4B,STMN2,PPID,RPL29,RPS7,CSNK1E,RPS4X,RPL28,RERE,RBBP7,HNRNPF,RUVBL2,EWSR1,RPS24,SRSF7,RPL31,SLC25A5,RBM3,PABPC1,RPS26,SP1,LMNB1,FBXW11,H1-10,SMARCE1,RPS29,HNRNPAB,RPL19,RPL10,APEX1,MATR3,ATP5F1B,RPL35,TUBB,RPL37A,SNRPD1,RPS9,FAU,PPP1CB,LCN12,RPL27A,G3BP2,HNRNPA0,HSPA8,SF3B1,HDAC5,FBXW4,RPS2,RPL10A,RPL24,H2AC14,MDM2,MRPL24,RPS16,RPL35A,RPS27L,RPL12,SSBP1,GTF2B,SRP14,SYNCRIP,ALYREF,ILF2,CBX3,DMAP1,RPL15,TP53,RPSA,MRPL11,MEPCE,RPS13,RPL17,H2AC6,KPNA2,HSPE1,RPL3,RPL23A,DHX9,PSME1,IGF2BP1,H2BC9,RPS17,RPL26,TUFM,NONO,SMARCA5,RPL7A,SUB1,VIRMA,RPL22,RPL13A,RPS20,MACROH2A1,RPS3,EIF4A3,RPLP0,CTDSP1,H2BC11,GRM2,RPS14,SNRPN,HSPA5,FBXW7,RPL4,DVL2,RPL27,GRIA2 |
| 1.055e-14 | -32.18 | PAGE4 (PAGE family member 4) | protein interactions | 9506 | 251 | 128 | 19454 | 5460 |
JAK1,RUVBL2,TRIM21,RPS24,SCYL2,HSPD1,SLC25A5,CCT8,PPAN,RPS4X,RPL28,HNRNPF,KCTD17,RUVBL1,PPP2R1A,RPL29,EEF2,PTS,RPS11,RPS23,TUBB4B,RPN1,NME1,RPL8,PHB1,SRSF1,DHX15,HSP90AB1,HNRNPL,TCP1,SPTAN1,RPL7,CCAR2,SNRPD3,YWHAG,QPCTL,RPL6,RB1CC1,RPL23,PPM1B,SF3B1,HSPA8,DDX5,XRCC5,EEF1G,PHB2,WDR77,RPL27A,EIF4B,SLC25A3,PRMT5,RPS9,VDAC2,DLST,CHCHD3,RPL10,RPL19,ATP5F1B,MATR3,PSMD4,PRDX2,SPINDOC,TAB1,PRPF31,MCM3,PSMA4,HSP90AA1,RPS5,CCT2,RPL3,HSD17B10,MAP1B,NKRF,TCOF1,TNKS2,RPS13,HUWE1,CSE1L,HNRNPK,THRAP3,LBR,EEF1A1,RPL15,IPO8,CCT5,ILF2,TNKS,RPL12,EEF1B2,RPL32,TMPO,RPS16,RPL35A,RBM17,RPS2,RPL10A,USP15,SMCHD1,RPL24,DLAT,PRDX6,RPL27,HSPA5,PFKFB2,RPL4,STK38,SPTBN1,SNRPN,RPL26L1,LMNA,HSP90B1,CMBL,RPS20,RPS3,ENO1,TUBA1B,UBB,BUB3,RPL13A,GMDS,TUFM,MAT2A,STK38L,RPL7A,IGF2BP1,OAT,ATP1A1,IVNS1ABP |
| 1.169e-14 | -32.08 | RPS5 (ribosomal protein S5) | protein interactions | 6193 | 376 | 175 | 19454 | 5460 |
PIK3R2,HMGB1,RPL4,FBXW7,NF2,UTP23,PIAS1,PNO1,SIRT7,RPA3,SQSTM1,METTL14,GRM2,RPL26L1,RPLP0,UBA52,RPS14,CDK7,RPL13A,COPE,SEC63,RPL22,METAP2,CCNF,RPS12,RPS20,PTEN,CDC73,AR,PPP1CC,TUFM,RPL26,MRPL22,RPS13,RPL23A,LLPH,TNFAIP8L1,SRP72,MRPL11,FBP1,RPL15,MAP1LC3B,EEF1A1,PRNP,RPL35A,MRPL24,CDK9,MDM2,KRR1,RCHY1,ARL10,RPL12,PRR3,MOV10,HDAC6,GPC1,G3BP2,EMC9,WDR77,H1-5,DYNLL1,RPL35,RPL19,SEC61B,RPS9,RPL37A,BRCA1,ZCRB1,CUL3,ACO2,RPS29,ZNF668,TRIM37,G3BP1,RAD21,RPS27A,RPS24,CHMP4C,EZH2,RPS11,E2F4,B3GNT2,RPL7,PHB1,RPL9,RPL8,RPLP2,RPLP1,PPM1B,RPL23,HNRNPA1,ATG7,RPS15,BAP1,RPL27,RNF113A,RPA2,KLF4,HEXIM1,FGF13,CFTR,RPL10L,SMURF1,RPS3,PSPC1,SEC61A1,FGFBP1,TRIM23,RC3H2,EIF3G,SPOP,RRP7A,UBE2H,ZBTB38,RPL7A,SLC25A1,RPS17,HNRNPK,RPL17,MEPCE,DHX9,RPL3,DNAJC2,TFCP2,GFM2,RPSA,UBL4A,H2AX,FZR1,CAND1,RPS16,SURF6,RBM42,RPL24,SNRNP70,RPL10A,RPS2,NOL12,ENY2,CSNK2A1,ADRB2,UFL1,RPS28,PYM1,HSPA8,PIH1D1,EIF4B,FGF17,RPL27A,RPL10,POLR2B,H1-1,POLR1B,RPS26,MYC,BTF3,H1-6,KRAS,RPS4X,RPL31,RAB4A,RPL18,RPS23,RPS7,MSX2,EEF2,H1-3,SNRPA1,DYNC1I2,RPS10,RPL6,WWP2,DDRGK1,CTNNB1,XPO1 |
| 1.194e-14 | -32.06 | RPS20 (ribosomal protein S20) | protein interactions | 6224 | 470 | 209 | 19454 | 5460 |
EXOSC1,IGF2BP1,UBE2H,RRP7A,EIF3G,RC3H2,RPS17,TNFAIP3,RPL7A,SMURF1,EIF4H,ADRM1,PSPC1,RPS3,HEXIM1,UBE2M,RPA2,CDC42,CFTR,ZC3H15,HSPA5,RPS15,LSM12,RNF113A,RPL27,BAP1,RPS2,RPL10A,TSNAX,MAP4,RPL24,SNRNP70,CSNK2A1,COPS5,ENY2,PLEKHO1,RBM42,RPS16,CAND1,FZR1,RPS27L,SYNCRIP,RPL32,RAD1,PIK3CA,DNAJC2,CAPZA2,UBL4A,RPSA,MEPCE,RPL17,CAPZA1,NEDD8,HNRNPK,RPL3,ABCE1,RPS26,H1-1,BTF3,PSMD1,CREBBP,MYC,SFN,PSMB6,ESR2,RPL10,APEX1,PSMD4,USP16,EIF4B,NUFIP2,PIH1D1,PALS2,PPT1,RPL27A,UFL1,FXR2,HSPA8,YAF2,DDX5,PYM1,RPS28,DRG1,AGR2,CTNNB1,DDRGK1,CNOT2,RPL6,WWP2,RPS10,TCP1,FUBP3,RPS23,RPL18,SOX2,RPS7,TOP3B,DHX38,RPS4X,TFG,HNRNPF,KRAS,NUP42,RPL31,PABPC1,REEP6,TXNIP,FBXO7,USP14,PPP1CC,TUFM,RPL22,RPL13A,GSK3A,PTEN,RPS12,CCNF,METAP2,RPLP0,CDK7,RPS14,UBA52,TPT1,PIAS1,AATF,NPM3,FBXW7,RPL4,HMGB1,RPA3,PNO1,HDAC6,SPATS2L,MDM2,CDK9,RPL35A,PRNP,PTPN1,RPL12,EIF4E2,ILF2,SRP72,RPL15,FBP1,YTHDF2,RPS13,EIF3E,TOM1,VRK1,TTC4,RPL23A,HSP90AA1,RPS5,LSM14B,RIT1,PDE4B,RPS29,ACO2,CUL3,CUL2,PRRC2A,RPL19,MRPL23,TSN,RPL35,LGALS3,RPL37A,SEC61B,RPS9,FAU,EMC9,LARP4B,GKAP1,H1-5,PGRMC1,G3BP2,GPC1,MCMBP,YTHDF1,RABAC1,TXNL1,RNF10,AHSA1,RPL23,MPHOSPH6,PSMD10,TRAF6,EIF3D,RPL7,RPLP1,RPLP2,RPL8,FOLR1,RPL9,PHB1,GPBP1L1,RPS11,EZH2,CHMP4C,RPL29,B3GNT2,NAA15,RAD21,TNF,G3BP1,TRIM37,ZC3H7A,RPS24,TRIP4 |
| 1.231e-14 | -32.03 | SF3A1 (splicing factor 3a subunit 1) | protein interactions | 10291 | 445 | 200 | 19454 | 5460 |
EMC2,ZC3H11A,HAPSTR1,TCOF1,PQBP1,MDC1,SNRPG,MRPL22,THRAP3,CTNNBL1,LSM4,HUWE1,DDX39A,CD2BP2,MIR15A,MIR200C,MIR25,PSMB1,LDLR,RCHY1,SMAD3,MIR106B,CWC15,ZBTB2,CDK9,NCBP2,THOC1,RPL35A,HDAC6,MOV10,MIR34A,PSMD7,TCEA1,PPIH,MIRLET7I,PRPF4,SIRT7,RPA3,MIR7-3,SNRPN,TXNL4A,RBFOX2,LSM2,TOX4,GSK3A,ENO1,EIF4A3,CCNF,VIRMA,YES1,DNAJC8,MIR145,BAG2,SRSF7,HNRNPA2B1,HSPD1,PPWD1,MCM6,GTF2E2,RAF1,TPBG,SNRPE,SF3B5,CHMP4C,MIR141,DHX15,WIF1,OCRL,TRA2A,HNRNPA1,PRPF19,SKIC8,DDX23,NKAPD1,MIR106A,COIL,PSMC1,GPC1,ACTL6A,WDR77,MFAP1,USP39,ZMAT2,SNRPD2,SNRPD1,ERH,SNRPB2,MAD2L1,MIRLET7D,MCM4,PRPF31,CUL3,MIR363,SP1,BRCA1,ABCE1,SNIP1,MIRLET7C,HNRNPK,CDC40,PSMA5,ACTR1A,TP53,CENPM,DDX42,UBE2N,ALYREF,SSBP1,SYNCRIP,CDC5L,MIRLET7G,CAND1,FZR1,CSNK2A1,RBM17,SMCHD1,SNRNP70,MIR10B,DDX46,BAP1,MIR107,RBM22,SNRNP27,PPP1R8,MIR34B,MIR7-1,HEXIM1,TFIP11,IDH2,ZNF326,RPA2,SRP54,PSMA6,SF3B6,SMURF1,STAT5A,SUGP1,UBE2H,RBM7,LSM6,TRIM21,PABPC1,HNRNPDL,CCAR1,NUP42,MIR155,USP30,KRAS,MSX2,SMARCB1,HDAC11,SMNDC1,MIR214,WDR82,EED,SRSF1,SUMO2,SNRPD3,SNRPA1,HNRNPL,DDRGK1,MIR29C,IFI16,MAGOH,MIR221,MIR31,STK26,EP300,DDX5,SF3B1,HSPA8,HDAC5,SLU7,DDX39B,SNRPA,SAP18,EMC1,UFL1,TRA2B,HNRNPA0,RALYL,ZC3H14,PSMB3,TRMT112,PIH1D1,GTF2F1,SF3B4,MIRLET7B,SMU1,ESR2,SNRNP40,SNRPB,TTC33,ZMAT3,PSMD1,HNRNPC,MYC,THOC6,CHTOP,CYP1A1 |
| 1.239e-14 | -32.02 | NTRK1 (neurotrophic receptor tyrosine kinase 1) | protein interactions | 4914 | 2058 | 728 | 19454 | 5460 |
CAMSAP2,RSBN1L,LYZ,AHSA1,MMUT,ATG7,STOML2,MRPS35,PSMD3,PRDX1,LRWD1,RPL7,SPTAN1,CCAR2,SNX1,KIF3B,OCRL,NOP58,HP1BP3,XPO5,TSG101,PHB1,DNM2,PLD3,STIM1,ACO1,FEN1,MARCKSL1,ANP32B,RFC3,AP1M1,PPWD1,ETFA,GNL1,G3BP1,ERP29,UBE3A,SLC39A7,JAK1,NDUFA4,MYO6,MCM3,RFC5,SAMHD1,CUL3,DBH,RPL19,RBBP4,SARM1,CPSF1,ABCB1,VAV2,EHD1,G3BP2,UNC45A,PSMC1,DNAJC7,ESYT1,HDAC6,ISYNA1,CAV1,G6PD,TOP1,EIF2B5,SEC23A,HSD17B11,AIFM1,DFFA,RAD23B,CASK,SRP72,ILF2,PPME1,YTHDF2,CCDC47,EIF3E,RNF20,SOCS2,OLA1,CTNND1,EMC2,HSD17B10,TMX3,ZC3H11A,EHD4,SLC25A10,XPOT,NONO,USP14,TUFM,GMPS,ATP5F1A,SEC63,TECR,RPL13A,TXN,ACAT1,TRIM24,RTRAF,PELP1,HSP90B1,P3H1,CDK1,EIF3J,SNRPN,SAP30BP,USP8,EIF5B,SQSTM1,MTDH,FADS2,YWHAB,FKBP4,TBC1D5,SHC3,LANCL1,TCP1,FAM98A,EIF2S1,AFTPH,PTK7,MTA2,KIF2A,TNPO2,NAA16,HNRNPDL,VDAC1,ZNF609,PDIA6,RUVBL2,RPAP3,PABPC1,RINT1,DNAJB6,ELAVL4,TBCE,PAPOLA,PSMD6,PSMD4,GTF2F2,PHKB,KLC2,PAK2,STAU1,HNRNPA0,LCN1,AKAP1,HSPA8,XRCC5,RFC4,RPL10A,NOS1AP,SNRNP70,TUBG1,CSNK2A1,CDC5L,ILVBL,AKR1B1,PREP,AIP,SYNCRIP,PSMC3,NHERF1,DNAJC2,IK,GPD2,UBIAD1,HADH,ACTR1A,CDK4,IPO8,L1CAM,KPNA2,IDH1,ABCE1,RPL3,SLC16A1,NAE1,ATP1A1,EIF3G,NCAPG2,TIA1,PTPN11,MAT2A,ROCK1,PPP1R10,CSTF3,RALA,EIF2S2,PSMA6,PAFAH1B3,PRKCA,IDH2,NTPCR,GTF3C4,SPTBN1,HSPA5,ZC3H15,KDM1A,PRDX6,APMAP,VCPIP1,HNRNPD,HAX1,HNRNPA1,NDC80,MAP1S,PIK3R1,PDIA3,NUF2,AGK,INA,ATP6V1A,SNX17,RPL9,SART3,PPID,BZW2,RPN1,RPL29,ACTN4,RBM12,ANP32A,SSRP1,ACVR1B,SRSF7,BAG2,SLC25A5,NEK9,NUDT5,SCYL2,LSM14B,RPS5,SCFD1,YWHAZ,RAB11A,PYCR1,ABHD12,TUBB,RANBP6,RPS9,POLR3B,RSRC1,TRMT6,ARCN1,SLC25A3,IRF2BPL,VPS18,VAPB,STXBP1,RGS19,SRM,CYFIP2,TXNL1,ATP2C1,HSDL1,BRD3,POR,TOMM70,DCK,CD2BP2,CCT5,HUWE1,IGF1R,FAF1,AP2A1,RHOBTB3,VIRMA,CTTNBP2NL,CTTN,CTNNA1,ENO1,EIF2AK2,GAB1,SLC12A2,PDHB,HELLS,DVL2,PRIM2,PPM1G,INPPL1,AVL9,NCK1,EXOC1,XPO1,YWHAH,RPL6,INPP4A,AASDHPPT,FUBP3,GYS1,HGS,PDHA1,TUBB4B,EEF2,TUBA1A,NUDCD3,DHX38,ETFB,TRMT1L,UTP25,PRPS1,CCAR1,PSMA1,HNRNPF,EWSR1,MYO1B,SERPINH1,CCT2,CPSF2,PSMD1,HNRNPC,LDHB,MYC,NCKAP1,APEX1,RPL10,POLR2B,CMTR1,VDAC2,CSNK1A1,EIF4B,ACAA2,EDEM3,SERPINB6,EEF1G,UFL1,GPHN,SF3B1,MAP4,KPNA1,SHC1,GAPDH,TPM3,API5,PPIL4,ESD,CAND1,GNPAT,MRPS9,DDX42,EXOC3,RPSA,RDH11,CSE1L,PSMA5,NUP107,PDE12,DHX9,CLPB,SOS2,PDCD4,PRKACB,SMARCA5,SLC25A1,CARS1,AKT1,DYRK1A,IDE,IRF2BP1,ELMO1,CTSB,CSNK2B,CDIPT,LUC7L3,CYC1,LEMD3,TFIP11,DDX46,TRAF6,DDX23,TRA2A,EIF3D,WDR11,CLPX,PRPF19,CACYBP,ERLIN1,SNX2,MYEF2,WDR6,THOC2,GTPBP1,VPS33A,GFPT1,TXNRD1,MCM6,VPS26B,ZC3H7A,ARGLU1,AKT2,TRIP4,MORC2,EXOC8,NTRK3,LMNB1,BLVRA,ATP1A3,GGH,RBM15B,MCM4,RNF40,PDE4B,PROX1,CUL2,TNPO3,GNB1,CHCHD3,DYNLL1,LRRC1,RAN,ADNP,MED23,PPP1CB,IDH3B,H1-5,WDR77,MCMBP,HADHA,NUP50,PSMD7,EXOC2,MFN1,LRRC40,CALR,ALCAM,CDCA3,HACD3,SRPRA,APEH,RPL15,EEF1A1,LBR,DDX39A,TBK1,IRGQ,MSH6,PRDX4,RPS13,ARF4,THRAP3,WASL,TOM1,PC,DLG1,EPHA2,CHORDC1,KPNA6,DEPDC1B,PYCR2,LDHA,GANAB,EIF4A3,QNG1,STUB1,OXSR1,TMOD1,ZNF574,RPLP0,MRPS34,JUP,LMNA,CNP,ELP3,RBFOX2,PSMC4,SMC4,HMGB1,RPL4,GTF2I,ARPC2,PRPF4,DRG1,HSPB1,NT5C2,PPFIBP1,PPIB,DYNC1I2,MAGED2,SRSF1,RPL18,CRKL,ARFGEF1,SUPT5H,RANBP1,RTCB,CCT8,TOP2B,POLR1B,SLC38A1,H1-10,FTSJ3,PPP5C,ATP5F1B,GTF2F1,PALS2,CTBP1,PLAA,EHHADH,PAFAH1B1,MRPS7,OXCT1,EMC1,SNRPA,USP15,RPS2,CDK12,KLHL22,COPS5,PGAM1,KARS1,RBM42,TMPO,DKC1,MIOS,EEF1B2,STT3A,TBC1D4,TFRC,WBP11,RAP1A,MTCH2,NAA35,RRM1,CAPZA1,FKBP8,SRPRB,TMEM33,ERO1A,SLC25A11,CALU,DNAJC10,EXOC5,VPS39,SRC,BCCIP,SRPK2,PPAT,BUB3,PSMC5,LIG3,ATL1,RPS3,ACACA,GSTP1,CAPN1,MARS1,EIF4E,EXOSC4,UGDH,DICER1,SYT4,ZNF207,VPS26A,DHX15,PPIA,SRSF10,RPL8,CTNNA2,ERLIN2,PPP2R1A,NAA15,CSNK1E,RAD21,SACM1L,COPS4,GTF3C3,DHX16,HECTD3,PCNA,HNRNPA2B1,HSPD1,HSP90AA1,PRPF31,PIK3R3,NIBAN2,ACO2,CLIC4,PRRC2A,USP5,TRIM46,MED17,LRRC8A,ENO2,FAM91A1,MFAP1,LARP4B,ISOC1,USP39,PSMB7,ACTL6A,PYGB,PSMA3,EXD2,OSBPL8,CNN3,ATP1B1,MOV10,MRPL24,COG1,RB1,PTPN1,VAC14,NDUFS3,ACTR2,PGM1,VPS16,FASTKD5,EGR1,VTA1,FARSA,SFXN1,TCOF1,NKRF,PPP1R12A,MAPRE1,HERC4,CDC73,ARFGAP3,CEP97,FERMT2,UBB,COPE,METAP2,HNRNPH3,RARS1,PICALM,DCTN4,UQCRC1,PCK2,SF3A1,BRIX1,PIK3R2,RTN4,ZKSCAN1,CBL,DDX1,AK2,GSTO1,CTNNB1,YWHAG,RAB5C,WWP2,CCT7,HSP90AB1,OSBP,HNRNPL,DBR1,WDR82,PSME2,SIN3A,PLS3,NCSTN,TMEM59,TFG,RPS4X,ROCK2,XPNPEP1,RUVBL1,PSMA2,CDK5,ABCF1,LSM14A,MDH1,CRMP1,PSMD14,CKB,PSMA4,SFN,HNRNPAB,NDFIP1,TAX1BP1,STAT1,MATR3,PRMT5,ATXN1L,FRS3,USP6NL,LAP3,ITGAV,PHB2,FXR2,TRA2B,SRSF2,NDUFS2,DDX5,DDX39B,SMG8,AKAP8L,SMCHD1,EDC3,LMAN1,CHGA,CPNE1,CDK6,ADD1,ALYREF,GNAI3,CERK,CAPN2,PIK3CA,RP9,RPL17,MEPCE,HNRNPK,MAP1B,SORD,OAT,GORASP2,ST13,CFL1,RPL7A,EIF4H,HPF1,SRP54,SEC61A1,GNAO1,PITPNB,PSPC1,UQCRC2,SSR1,UGP2,GRPEL1,FTSJ1,GFM1,DLAT,PGK1,PML |
| 1.295e-14 | -31.98 | AIFM1 (apoptosis inducing factor mitochondria associated 1) | protein interactions | 9131 | 601 | 255 | 19454 | 5460 |
COPS5,COX5A,KARS1,AKAP8L,SMIM12,SNRNP70,SHC1,UBE2N,COX4I1,CD274,SSBP1,SYNCRIP,SURF6,CAND1,FZR1,APOO,HADH,H2AX,GLRX5,TP53,FAM162A,SNAP29,ATP5PB,KBTBD4,SLC25A24,NUPR1,COX19,GPD2,TFCP2,ABCE1,CLPB,ATP5PF,PSME1,SLC25A11,MAP1B,FKBP8,PSMB10,AKAP12,CARS1,NAA50,NDUFAF2,UBE2H,OAT,ATP1A1,CHCHD4,RC3H2,CISD1,EIF3G,MRPS28,UQCRC2,IDE,SUCLG2,ADRM1,NTPCR,CFTR,CDC42,HECTD1,ACACA,CYC1,SCLT1,SAMM50,IDH2,STX17,RPA2,RNF113A,GFM1,GRPEL1,SLC25A51,TDRP,DDRGK1,NDUFV2,HSPB1,DRG1,UQCC6,PEX3,CDC23,AGR2,AK2,HDHD5,FUBP3,LANCL1,RMND1,UQCRH,ADCK1,SOX2,SERPINA3,TUBA1A,ETFB,ARFGEF1,FAM136A,HDAC11,PDHA1,NUDT19,TUBB4B,RUVBL2,CCT8,NDUFB5,VDAC1,SLC20A2,RUVBL1,HNRNPF,USP30,BAG3,MLF2,PSMD1,MYC,COX6B1,SERPINH1,H1-1,ICAM1,H1-10,COX16,KIAA1191,CKB,DLST,TACO1,VDAC2,PSMD4,ATP5F1B,TOMM22,TIMM10,NCOA5,PIH1D1,AKAP1,EP300,COX17,HSPA8,HIGD2A,STAU1,ADRB2,PHB2,OXCT1,SLC31A1,NDUFS2,UFL1,FXR2,ATP5MG,GRSF1,CDCA3,TES,RCHY1,PTPN1,TIMM8B,AIFM1,SLC25A12,MRPS23,DBT,ATP5PD,CDK9,TOMM70,PTP4A3,TIMM8A,BCS1L,MTARC2,PPIF,DHRS7B,NDUFS3,HSD17B10,SFXN1,RAB1A,ARF4,HSPE1,TUFM,ATP5F1A,FBXO7,PYCR2,NDUFB10,PPTC7,CTU1,ACAT1,CHCHD6,CCNF,GXYLT1,VIRMA,ARMC6,TXN,UQCRC1,SLC35E1,UBA52,ARHGAP1,TIMMDC1,PCK2,OXSR1,GRM2,TIMM23,COX6C,TMEM126B,RTN4,SQSTM1,MAVS,RPA3,DVL2,POLDIP2,UQCC3,FBXW7,CLPX,TST,HAX1,MRPS26,DCAF11,PSMD10,MRPL18,PHB1,NDUFS8,EGLN3,KCTD10,HOXB1,FAF2,RAF1,LYPLA1,B3GNT2,CYB5B,NDUFS6,SLC25A23,OPA3,JAK1,SLC39A3,HNRNPA2B1,SLC25A5,IMMP2L,ETFA,TOMM40,PYCR1,CUL3,PMPCA,GRB10,CUL2,ILK,HTRA2,NOA1,BLVRA,MED10,PELO,FAM91A1,MAD2L2,PARL,NDUFAF4,CHCHD3,DYNLL1,TUBB,ACTB,TIMM29,TIMM13,MTX2,MYL6,NDUFA5,SLC25A3,ATP5PO,HADHA,CMC4,ATP5F1E,EXD2,FBXL4,ATAD1,UCHL3 |
| 1.296e-14 | -31.98 | RNF113A (ring finger protein 113A) | protein interactions | 7737 | 688 | 285 | 19454 | 5460 |
SYNCRIP,SDHB,RPL32,ALYREF,DSTN,RPS16,CAND1,NKAP,ILVBL,TMPO,SURF6,CDC5L,KARS1,CSNK2A1,ELOC,GAPDH,TUBG1,SNRNP70,H2AC4,RPL24,AKAP8L,RPS2,RPL10A,MAP4,MYD88,SNIP1,SLC25A11,RPL3,MRPS18B,DHX9,KPNA2,TMEM33,CSE1L,HNRNPK,MEPCE,RPL17,RP9,CBX3,IK,CAPZA2,RBM34,NHERF1,RPS3,PSPC1,UQCRC2,PSMA6,CALML5,SRPK2,RSL24D1,SLC25A1,RPF2,RPL7A,RPS17,CFL1,CNNM4,DNAJC10,ATP1A1,CDKN2AIP,RPL27,DDX46,BANF1,EXOSC4,RNF113A,DERL1,KDM1A,RPS15,EIF4E,MARS1,HSPA5,GTF3C4,NTPCR,SMYD3,ZNF770,ACACA,LUC7L3,SIN3A,FBXO31,SRSF1,MAGED2,RPS10,HNRNPL,SNRPD3,LYAR,HSP90AB1,DDX50,RPL6,DNTTIP1,DCAF5,MGMT,HSPB1,RPL31,LSM14A,PABPC1,ABCF1,RUVBL2,EWSR1,RTCB,HNRNPF,ZNF609,VDAC1,RUVBL1,RPS4X,RPL28,CCAR1,POLDIP3,RERE,TRMT1L,H1-3,EEF2,TUBB4B,MTA2,ZRANB2,RPS23,CRKL,RPL18,VDAC2,MIDEAS,PRMT5,FAM83B,MATR3,RPL10,APEX1,HNRNPC,BAG3,BRMS1,MRPS25,FTSJ3,CHTOP,H1-10,RPS26,DNAJB6,RPS28,XRCC5,APPBP2,SF3B1,HSPA8,DDX5,UBE2D3,TRA2B,FXR2,STAU1,EEF1G,SAP18,NUP62,RPL27A,EIF4B,NUFIP2,CSNK1A1,AIFM1,RPL12,TES,RPL35A,SEMA3C,G6PD,MOV10,GRSF1,SLC2A1,SLC25A10,NKRF,TCOF1,RPL23A,PC,FARSA,THRAP3,CTNND1,RPS13,PRDX4,MSH6,YTHDF2,AURKAIP1,EEF1A1,RPL15,LLPH,PPP4C,TUBA1B,CTTN,PRKRA,SENP5,RPS20,RPS12,TXN,RPL13A,TECR,RPL22,ATP5F1A,RPL26,TUFM,NONO,PPIG,PPM1G,RPA3,SQSTM1,EIF5B,NPM3,RPL4,MBD3,BRIX1,RPS14,UBA52,EEF1E1,SNRPN,EIF3J,LMNA,TIMM23,RPLP0,RARS1,IFRD1,RPL8,RPL9,MYEF2,XPO5,HP1BP3,RPLP1,RPLP2,RPL7,AGK,PPIA,EGLN3,DHX15,PRDX1,PRPF19,TRIM8,HSPB8,HNRNPA1,WDR12,DDX23,HAX1,HNRNPD,RPL23,DICER1,ZYX,HSPD1,SLC25A5,HNRNPA2B1,ARGLU1,PCNA,RPS24,SRSF7,RBBP7,G3BP1,CHN2,MRPS17,RPS27A,FOXP4,RFC3,NUP153,RPL29,PPP2R1A,GFPT1,RPS11,SART3,FAU,ZNF22,RPL37A,RPS9,RPL35,RBBP4,TUBB,CHCHD3,PRRC2A,RPL19,ERH,CUL3,NOP16,CUL2,CFAP20,SAMHD1,ZNF668,LMNB1,RPS5,RIT1,EEIG2,CXCR4,NUP50,HADHA,COIL,G3BP2,SKP1,H1-5,FEM1A,LARP4B,PCLAF,MFAP1,MYL6,SLC25A3 |
| 1.335e-14 | -31.95 | VAPA (VAMP associated protein A) | protein interactions | 9218 | 659 | 275 | 19454 | 5460 |
LEPROTL1,TOMM6,KRAS,VDAC1,PDIA6,SEC11A,CYP2C9,RND3,NDUFA12,PTRH2,DNAJC25,CCDC134,ISG15,COX14,AFTPH,RAB1B,OSBP,SIN3A,RAB35,NDUFB8,YWHAB,DEGS1,DCAF5,AGR2,YWHAH,NDUFV2,PPIB,YWHAG,STK4,LAMP2,RAB5C,EMC1,NDUFS2,GOSR1,PHB2,ADRB2,HSPA8,RAB5A,NANP,JAGN1,CAV2,UBAC2,YIPF5,SEC62,VAMP1,PTAR1,GOSR2,BET1,ESR2,RETREG3,SF3B4,VDAC2,LMBR1L,CMTR1,RPS26,SERPINH1,ZMPSTE24,SPCS3,FBXW11,BTF3,TMEM38B,OST4,COX6B1,MYC,TMED5,FKBP8,PSMA5,TMEM33,RAB3B,SRPRB,ERO1A,ABCE1,YIF1A,BCAP29,CYBRD1,SURF4,LMAN1,SELENOI,TMPO,RBM42,SURF6,DNAJC1,TMED9,RPS16,RAC2,XXYLT1,COQ8A,STT3A,COMT,NDUFB4,COX4I1,CAMLG,CD81,DPP4,MTMR12,HSPA5,DERL1,RAB9A,DDX46,APMAP,TMX2,PRKCA,LUC7L3,RPA2,SSR1,FGFR1,CDC42,CFTR,KLRD1,DYRK1A,MACROH2A1,UQCRC2,UBE2H,CALU,KCNB1,ENDOD1,DNAJC10,PRKACB,SLC25A1,RAB2A,VAMP5,MORF4L1,FLOT1,SACM1L,EMC8,SLC39A7,ERP29,UBE3A,TMT1A,VAMP2,STIM1,RPN1,NGB,NDUFS6,CTSA,ERLIN2,RAF1,NEU1,NDUFS8,EGLN3,ERLIN1,STK3,WDR44,SNX2,GJA1,ATP6V1A,CCDC127,MRTO4,PHB1,C2CD2L,STX1A,RB1CC1,RHOG,ATG7,PDIA3,PTPN5,MARCHF5,STOML2,PXMP2,STX7,ATP6V1G1,ATAD1,SRI,OPRK1,PMAIP1,TTC1,DNAJC3,DUSP9,FKBP10,NDUFA5,ARCN1,VAPB,OTULINL,RND2,PGRMC1,CHCHD3,ABHD12,GNB1,TENT5C,SPCS1,RMDN3,SEC61B,GPR89A,TMEM229B,PIGK,EIF3K,CYB5R3,NTRK3,SCFD1,VMP1,LMNB1,CYB561,YWHAZ,TOMM40,ACO2,SCN3B,RAB11A,OPRM1,ARF4,PDE2A,PRDX4,RIGI,DNAJC30,GNG5,TMX3,IGF1R,EMC2,HSD17B10,RAB1A,LTBR,FAF1,TMED1,SOD2,SRP72,HSPA13,LBR,BCS1L,SERPINB9,CCDC47,GBE1,NDUFA2,CDK9,SLC25A12,CAV1,ARF6,PRNP,HSD17B11,CLN8,CHID1,PTPN1,HACD3,H2AZ1,POR,ESYT1,LAMP3,HDAC6,TMEM199,H2AC14,CALR,SLC25A46,TMUB1,SPCS2,SQSTM1,RTN4,RPA3,HELLS,RPLP0,PITPNA,LMNA,P3H1,COX6C,STOM,HSP90B1,METTL14,FAXC,UQCRC1,GABARAPL2,ST7,SYNRG,ATG16L1,PHTF2,TECR,VIRMA,SEC63,MGST3,PNP,COPE,RHOJ,GANAB,CHCHD6,CCNF,GXYLT1,SELENOT,METAP2,SYP |
| 1.350e-14 | -31.94 | RPL30 (ribosomal protein L30) | protein interactions | 6156 | 437 | 197 | 19454 | 5460 |
RPL32,DNAJC1,CAND1,RPS16,FZR1,DKC1,RBM42,TMPO,SURF6,ENY2,COPS5,RPL24,SNRNP70,RPS2,RPL10A,RPL3,IMP4,MEPCE,RPL17,UBL4A,TP53,RPSA,DNAJC2,RBM34,PSPC1,RPS3,RPL10L,RSL24D1,RPF2,SMARCA5,RPL7A,VAMP5,ZSCAN25,SPOP,EIF3G,RC3H2,UBE2H,BAP1,RPL27,SNAPC1,NLE1,RNF113A,RPS15,CFTR,RPA2,WWP1,HEXIM1,ZNF770,EED,RPS10,LYAR,HSP90AB1,DDX50,WWP2,RPL6,CTNNB1,DDRGK1,IKBKB,FOSL2,NCK1,POU5F1,DRG1,RPL31,OAS1,H1-6,KRAS,VDAC1,RPS4X,RPL28,SOX2,RPS7,MSX2,RAB4A,PDHA1,RPS23,RPL18,DLST,ZNF189,CMTR1,NFKBIB,RPL10,MYC,BTF3,PSMD1,FTSJ3,RPS26,ICAM1,POLR1B,ARMC7,NSA2,MAF1,YAF2,UFL1,STAU1,RPL27A,PIH1D1,RPL12,EFNA3,RCHY1,CDK9,NFKB1,MOV10,GRSF1,EMC4,HDAC6,NKRF,RPL23A,HAPSTR1,HSD17B10,PAK1IP1,HUWE1,VRK1,RPS13,RIGI,FBP1,EEF1A1,MAP1LC3B,MAP2K3,RPL15,FCF1,LLPH,ZFAND2A,SRP72,CCNF,METAP2,PRKRA,RPS20,PTEN,RPS12,RPL13A,RPL22,RPL26,DNAJC8,USP14,PPP1CC,SOD1,RPA3,MME,SIRT7,GTF2I,HMGB1,RPL4,FBXW7,PIK3R2,BRIX1,RPS14,RPL26L1,RPLP0,ZNF574,RPL8,FOLR1,RPL9,PHB1,RPLP1,HP1BP3,RPLP2,NOP58,G0S2,RPL7,MAP3K14,DICER1,RPL23,RPS24,G3BP1,EMC8,TRIM37,PSMD12,RAD21,RAF1,B3GNT2,MAK16,RPL29,EZH2,NGB,RPS11,JPT2,ZNF22,RPL37A,POLR3B,SEC61B,RPS9,RPF1,RPL35,TUBB,RPL7L1,RPL19,ACO2,CUL3,ZNF668,RPS29,BRCA1,HSP90AA1,RPS5,RIT1,NOP53,G3BP2,EMC9 |
| 1.392e-14 | -31.91 | negative regulation of cell population proliferation | biological process | GO:0008285 | 791 | 332 | 18204 | 5365 |
CDKN2C,TRIM32,CCN3,MIR145,MSX1,TMIGD3,ING1,DUSP1,PHB1,HMGA1,TWSG1,VSIR,ADIPOQ,TNF,SMAD3,RAF1,CERS2,MIR1298,MIR24-1,RBPJ,ATRAID,IL10,XCL1,MIR98,FBXW7,NKX3-1,TESC,FCGR2B,NOG,EAF2,MIR23A,HRAS,PLG,MIR361,STK11,DUSP10,MIR495,MIR205,TMIGD1,DDAH1,SAV1,BCL6,MINAR1,LBX1,CCL23,KLF10,ILK,ARG2,MIR16-1,CACNB4,P3H1,MIR424,RB1,IL2RA,NHERF1,TNFRSF14,BMPR1B,INPPL1,NPPC,CCL2,POU1F1,NUP62,RBM5,PML,HPGDS,CDKN1A,CLDN3,PTHLH,AIF1,RNF10,SFTPD,CSNK2B,PDCD1LG2,MIR378A,TRIB1,CTLA4,PPM1D,DDR1,MIR214,TLR2,CYP1B1,FKTN,MIR222,TES,PDCD4,MIR1-1,PRKRA,SYNJ2BP,MIR34A,SOD2,MIR15A,MIR143,ATG101,MIR133B,MIR34B,IFT52,MIR188,SDC4,CXCL8,MIR873,STK4,IDO1,IFNG,TP53,PHB2,KLF4,CCL8,AZGP1,KRIT1,CD200,MIR140,CDK6,CER1,PMP22,RNF41,VASH1,GABBR1,ACKR3,NME1,RB1CC1,SST,ADORA3,ADRA1A,SH3BP4,ADORA1,MIR34C,SIX5,ADGRG1,MIR195,BMPR2,B2M,NF2,MIR29A,RNF139,MIR335,WDR6,TPBG,MIR137,MIR638,SLC6A4,PTGDS,TGFB1I1,MIR181C,CYP27B1,SMARCB1,CNOT7,MIR218-1,PPARG,NIBAN2,MIR503,CGRRF1,SHOC2,TNFRSF9,CTNNBIP1,RXFP2,SFRP4,BTG2,TSPO,NR2E1,MIR193A,PDE9A,CDKN1B,IRF1,MIR711,GPNMB,OSM,MIR30E,RBBP4,CTNNB1,FGF10,TNFAIP3,GSTP1,VDR,BAK1,ADAMTS1,MIR9-1,IRF6,PDCD10,WDR77,MIR675,IL1A,TGFB2,OVOL1,TAX1BP3,MIR152,H2AC6,CDH13,PROX1,CXCL1,CEND1,SMAD4,GREM1,MIR182,SPINT2,GAS8,LMNA,SOX2,TMEM115,FABP7,TGFB3,IL1B,TOB2,LTA,HGS,CTBP1,MAP2K1,BTG3,B4GALT7,MED31,SMAD1,TSG101,PTEN,MIR29C,JAK2,LIMS2,STAT1,MIR339,MIR125A,B4GALT1,CAV2,SKAP2,ING5,PLA2G5,IFI35,SNAI2,BECN1,IL2,ATP5IF1,DICER1,MIR221,MIR497,TRIM24,AR,DLG1,MIR492,DLG3,MIR320A,MIR20A,GHRL,RGN,OGN,EIF2AK2,CTNNA1,NDFIP1,H2AC4,SOX9,BAX,IFT172,MYC,TP53INP1,FLCN,SFRP1,MIR126,CSK,IL6,CD86,BTG1,FTH1,NUPR1,PTGES,CASK,ACVR1C,MIR223,MIR185,IL12B,PRNP,MIR10A,SPRY1,BTN2A2,TMEM196,MIR449A,OPRM1,PELI1,STK3,PRL,PDCD5,FRZB,ATP5F1A,CD274,FOXP3,SCG2,IL12A,MIR132,KLF9,LILRB1,APLN,CDKN2D,BAP1,PIM2,VGLL4,MIR129-1,CD80,MEF2C,RERG,MSTN,LDOC1,EEF1E1,CAV1,PAX6,PRDX4,TYROBP,MIR204,ZBTB17,NMI,WNT10B,NACC2,MIR149,SFN,S100A11,CDKN3,AQP11,IGFBP3,MSX2,PTN,CDC73,MIR21,FGFBP1,MIR30B,DNAJB2,CD9,MIR96,LILRB4,MIR146A,TMEM127,IFNK,IL20RB,SMAD2,MIR342,IFT57,ZBTB16,RGCC,LST1 |
| 1.404e-14 | -31.90 | RPS27A (ribosomal protein S27a) | protein interactions | 6233 | 393 | 181 | 19454 | 5460 |
STAU1,UFL1,PEBP1,PIH1D1,CNPY3,PSMB3,RPL10,USP38,PSMB6,TAX1BP1,PSMD6,PSMD4,H1-1,RPS26,PSMD14,BTF3,KANSL3,PSMD1,THAP7,PSMA4,MYC,RPS4X,KRAS,PSMA1,FAM168A,RUVBL2,EWSR1,RPL31,RPS23,TAF10,RPL18,H1-3,SOX2,ISG15,MED9,ERRFI1,RPS10,EED,SRSF1,CBL,NCK1,ARL14EP,CTNNB1,DDRGK1,WWP2,RPL6,LITAF,RNF113A,PML,SNAPC1,BAP1,HEXIM1,UBE2M,WWP1,SMURF1,PRKCE,ADRM1,RPL10L,MAP3K3,FGFBP1,PSMC5,PSMA6,RPS3,UBE2H,ATP1A1,RC3H2,TRIM23,RPL7A,AKT1,PSMB2,RPL17,MEPCE,NEDD8,NUPR1,PSMC3,NECAP1,ACVR1,H2AX,TP53,RPSA,UBL4A,KBTBD4,RPS16,SPPL3,TRMT10B,SYNCRIP,RPL10A,RPS2,H2AC4,RPL24,SMAD4,E4F1,DNAJB2,RNF11,NOP53,PSMA3,NMRAL1,CRY1,WBP2,PSMB7,NOTCH2,PLSCR4,WDR77,RPL19,RPL35,AP2M1,RPL37A,RNF208,RIT1,RPS5,ZCRB1,MYO6,CUL3,ACO2,RAD21,PSMD12,RPS27A,TRIM37,RPS24,ZC3H7A,HNRNPA2B1,RPS11,CHMP4C,MAK16,B3GNT2,ZNF263,RPLP1,RPL9,RPL23,TRAF6,HNRNPA1,PTPN5,MTRF1,PSMD3,AATF,RPL4,DESI1,SQSTM1,MTRES1,RPLP0,GRM2,UBA52,VIRMA,RPL22,SH3BGRL,RPL13A,COPE,PTEN,TRIM24,RPS12,UBASH3B,PRKRA,CTTN,GAB1,OPTN,SMAD2,CDC73,PPP1CC,USP14,RPL26,LRRC73,PTGES3,FBXO25,RPS13,VRK1,BACH1,SEM1,RPL23A,HAPSTR1,RNF181,RPL15,SMAD1,MAP1LC3B,MRPL11,MDM2,PSMB1,ARL10,KRR1,HRAS,HDAC6,BMPR1B |
| 1.407e-14 | -31.89 | mitochondrial inner membrane | cellular component | GO:0005743 | 489 | 221 | 19108 | 5553 |
AGK,TOMM40,MRPL41,PLA2G4B,SPHK2,GRPEL2,UQCC2,PTPMT1,PDSS2,MGARP,COX16,TMEM126A,DUSP18,MRPL51,COX6B2,MPV17,MRPS9,MRPL24,STOML2,MRPL57,GHITM,SLC25A28,CHCHD3,CPT2,TIMM23,ATP5MC3,ATP5MG,SLC25A12,SLC25A5,DUSP21,PHB2,MRPL16,TMEM11,NDUFA4,NDUFS2,PMPCA,NDUFB10,CRAT,TWNK,MRPS23,MRPL9,MTG2,COX8A,COX6A2,SRC,COX4I1,HADHA,ADCK1,MPC1,SLC25A10,UQCRC1,ATP5F1A,MRPL20,COX11,MAIP1,MRPL33,CYP11B2,UCP2,TAMM41,HSPD1,LDHB,MRPS18C,COX6C,MRPL50,ATP5MK,NDUFA12,RSAD2,MRPS18A,COX6B1,DNAJC30,TMEM70,NDUFS3,CIBAR1,NDUFS8,MRPS35,TIMM8B,NDUFAF3,TIMMDC1,MRPL10,CLU,GRPEL1,UQCC3,MRPL17,FGR,NDUFA1,MRPL12,LGALS3,APOO,ATP5F1D,SLC41A3,SFXN1,TIMM13,CYP27A1,MRPL49,SLC25A42,CHCHD6,RPS3,SLC25A27,NDUFB8,COX10,AURKAIP1,MRPS34,SLC25A20,COA1,SLC25A51,UQCC6,MRPS21,MRPL11,AIFM1,NDUFB7,COX7B2,ATP5PD,UQCRH,SLC25A3,SLC25A24,SLC25A23,UQCRQ,TYMS,BOK,TMEM160,ATP5MC1,COX20,MRPS18B,MRPL22,TIMM29,NDUFAF4,NOA1,HIGD2A,PTPN1,PLSCR3,SLC25A26,NDUFAF2,COX7A1,NDUFAF6,MRPL13,ATP5PB,PGS1,SAMM50,MRPS26,NME4,MRPS11,EFHD1,IFI6,ATP5PF,MTG1,SLC25A11,MRPS33,KGD4,MTHFD2L,MRPL23,TAFAZZIN,NDUFC2,MRPS28,SLC25A31,CNP,MRPL34,MRPS25,NDUFB6,CHDH,BCS1L,COX7B,NDUFA5,TIMM8A,MRPS16,TIMM17A,ROMO1,COX5A,MRPL52,SLC25A21,SLC25A45,MRPS7,MPV17L2,MRPL47,NDUFA2,MRPS17,COX4I2,CLPX,TRMT10B,PPIF,DNAJC19,PARL,PDE2A,MRPL40,MRPL18,IMMP2L,CYP1A1,SFXN2,COQ10B,SLC25A32,CHCHD1,TMEM126B,SMDT1,SDHB,NDUFAB1,GPD2,TIMM21,DELE1,SDHC,PHB1,NDUFS6,ATP5F1B,SLC25A14,NDUFB4,CYC1,NDUFV2,UQCR11,PSEN1,TIMM10,SLC25A4,MTX2,MRPL36,SLC25A39,CYP11B1,NDUFB5,TMEM177,ATP5F1E,UQCRC2,SLC25A1,ATP5PO,MRPL53,BCL2L1 |
| 1.436e-14 | -31.87 | CUL4A (cullin 4A) | protein interactions | 8451 | 836 | 335 | 19454 | 5460 |
CTBP1,CYP3A5,FDFT1,ZER1,KLHL3,PAFAH1B1,PSMB3,SHMT1,ELK4,UBE2D3,STAU1,RANBP10,GNB4,DDX39B,SNRPA,HSPA8,YAF2,EP300,LCN1,DDX5,LAMTOR1,H2AZ2,FBXW11,COP1,H1-1,COPS7A,MYC,HNRNPAB,PBLD,NXPH3,HMGCS1,BAG3,SNRPB,ATP5F1B,STAT1,SNRNP40,POLR2B,RPL10,DES,NCKAP1,DDIT4,ATXN1L,PRMT5,ANAPC2,DCAF8L2,TUBB4B,MOB3C,DCUN1D5,GCLC,DHX38,GPT,RANBP1,SOX2,HNRNPF,PSMA2,RUVBL1,XPNPEP1,HNRNPDL,TFG,IMPA2,PABPC1,RUVBL2,EWSR1,IKBKB,DCAF5,FKBP4,POU5F1,DDX1,CDC23,DRG1,DCAF4L2,IFI16,RAB5C,XPO1,YWHAG,CTNNB1,TBC1D10C,HNRNPL,RAB1B,SNRPD3,HSP90AB1,MACROD1,FABP5,GNB3,GSTA1,ANXA4,WDR82,CORO1C,EED,RPA2,UBE2M,RAG1,CDC42,WSB1,HDAC3,H2AC13,GRPEL1,MARS1,HSPA5,UGDH,RPL27,BANF1,LSM12,LCP1,PRDX6,RAB9A,SPOP,UBE2E3,DNAJC10,PDCD4,IGF2BP1,DTL,OAT,ATP1A1,SMARCA5,RPL7A,CFL2,FBXO44,TIA1,PHKA1,PCBD1,ST13,CTSB,BUB3,RPL10L,IDE,ROCK1,RPS3,CBX3,DCAF12L2,ACVR1,HBP1,CARD19,SESN2,BIRC5,TP53,CDK4,RAP1A,HADH,NEDD8,H3C1,HNRNPK,CRYBA4,FKBP8,MAP1B,PSME1,POC1B,ABCE1,DHX9,TUBG1,SNRNP70,H2AC4,KPNA1,RPS2,RPL10A,MAP4,KARS1,SCGB1D1,COPS5,GAPDH,CAND1,FZR1,LMAN1,SSBP1,COQ8A,PREP,RAP1B,ADD1,XXYLT1,VAV2,RNF7,SLC25A3,ANXA7,TOR1AIP2,DET1,CDKN1A,CDSN,POLA2,ASB3,SKP1,FBXW4,CRY1,SENP8,DCAF4,SCFD1,TNFAIP8,HSP90AA1,NLRP3,CUL3,CUL2,SAMHD1,RNF40,IP6K1,MTM1,RBBP4,TUBB,RPL19,JAK2,GNB1,ENO2,SNRPD1,SEC61B,STIM1,CHMP4C,RPS11,OTULIN,SNRPE,RAF1,CSNK1E,GIN1,GFPT1,PPP2R1A,DCUN1D3,RBBP7,G3BP1,AP1M1,PSMD12,RPS27A,PDE6A,COPS4,SSRP1,RAD21,HSPD1,SLC25A5,NEK9,HNRNPA2B1,SLC39A7,PCNA,SLC39A3,UBE3A,MRPS11,UBE2D1,SKIC8,HNRNPD,HAX1,LYZ,DCAF11,LST1,CDKN1B,DICER1,PRDX1,STOML2,BCL7C,FIG4,WDR11,FEM1B,COPS7B,DHX15,LRWD1,FBXO32,PPP2CB,TSG101,RPLP1,RPLP2,CYB5A,COPS2,FBP2,LMNA,HSP90B1,HNRNPH3,OXSR1,WDR5B,PCK2,RPS14,UBA52,DDAH1,SEC22B,ARHGAP1,ST7,NF2,RPL4,NUCKS1,VPS28,INPPL1,RPA3,SLC39A9,HELLS,SIRT7,DCAF16,SMAD2,CA2,PNPO,CTSD,SEC13,RPL26,B3GALNT1,FERMT2,VIRMA,RPL22,SMAD5,ENO1,TUBA1B,SYT2,ZBTB18,RPS20,PTEN,VAC14,ILF2,SRP72,GBE1,CCT5,EEF1A1,ING1,DDX39A,MAP2K3,UBE2V1,RPL15,SOX9,GGCT,CAMK2G,TTC4,VTA1,SOCS2,RIGI,RAB1A,TLR4,SFXN1,RING1,MRFAP1,RPL23A,HSD17B10,CRBN,FOXP1,NFKB1,H2AC14,KLHL9,ISYNA1,TLE1,DCUN1D1,POLE3,MDM2,HRAS,DECR2,NLRP1,TES |
| 1.442e-14 | -31.87 | IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3) | protein interactions | 10643 | 496 | 218 | 19454 | 5460 |
HNRNPK,KPNA2,MIRLET7C,MEPCE,MIR16-2,MAP1B,MIR200A,SLC25A11,RAB27A,MRPS18B,MIR9-3,IDH1,DHX9,NEFL,CDK4,RPSA,TP53,DUSP1,FZR1,RPS16,CAND1,MIRLET7G,TMPO,RBM42,MIR429,SYNCRIP,MRPS9,ALYREF,SNRNP70,RPS2,RPL10A,COPS5,RPS15,EIF4E,MIR107,MIR29A,BAP1,MIR10B,BANF1,RPA2,EIF2B3,GSTP1,MIR21,HEXIM1,KLF4,HECTD1,MIR7-1,MIR34B,CFTR,DYRK1A,RPS3,PSPC1,SPOP,RC3H2,ELAVL2,IGF2BP1,UBE2H,RAB2A,RPL7A,RPS17,MIR155,RPS4X,RPL31,ABCF1,MIR9-2,PABPC1,LSM14A,CCT8,RBM3,TRIM21,MIR206,RTCB,HDAC11,RPL18,RPS23,MIR222,RPS7,HNRNPL,RPS10,PAIP1,EIF2S1,MIR9-1,LAPTM4A,MIR214,MIR31,MIR221,DDX1,MIR140,DRG1,MIR143,RPL6,MIR29C,MRPL9,CPEB1,DDRGK1,UFL1,STAU1,SNRPA,RFC4,NGRN,DDX5,AKAP1,NUFIP2,PABPC5,USP16,MATR3,CMTR1,MIRLET7B,MRPL13,MRPS25,APOBEC3B,MYC,BTF3,SNRPB,RPS13,RPL23A,HAPSTR1,MIR20A,MIR17,ILF2,MIR200C,APOBEC3D,MIR15A,EIF2B2,MDM2,DBT,MRPS23,SRP14,MIR106B,ARL10,PRR3,MIR25,MIR34A,GRSF1,MOV10,FBXW7,RPL4,MIR7-3,AATF,CRYZ,RPA3,SIRT7,MIR205,MIRLET7I,SQSTM1,MIR34C,CDK1,MRPS34,RPL26L1,MYL12B,CCND1,MIR1-2,KLF12,RBMS2,TMOD3,RPL22,VIRMA,MIR16-1,CCNF,METAP2,TUBA1B,EIF2AK2,GSK3A,RTRAF,TRIM24,RPS20,MIR145,AP2A1,CNTNAP1,NONO,USP14,PPP1CC,G3BP1,SSRP1,SLC25A5,PPAN,HNRNPA2B1,ZC3H7A,MRPS11,SRSF7,SKA3,CHMP4C,NME1,RPS11,SNRPE,RAF1,KCTD10,RPL8,PHB1,MIR7-2,MIR141,RPLP2,MIR1-1,RB1CC1,BCL2L1,RPL23,HMGA1,MRPS35,HNRNPA1,MIR106A,G3BP2,LARP4B,MYL6,ACTB,TUBB,MIRLET7D,NDUFAF4,ERH,MAD2L2,RPL19,RPL37A,RPS9,BRCA1,MIR363,HSP90AA1,CUL3,MIR98,RPS29 |
| 1.456e-14 | -31.86 | YBX3 (Y-box binding protein 3) | protein interactions | 8531 | 374 | 174 | 19454 | 5460 |
CUL2,CUL3,MIR98,DCAF4,MIR363,NLRP3,PELO,RPL35,RBBP4,MIRLET7D,RPL19,PRRC2A,H1-5,CSRP1,MIR106A,HNRNPA1,MIR1-1,IFIT2,PHB1,MIR7-2,MIR141,B3GNT2,RAF1,E2F4,ACTN4,EZH2,SART3,PPAN,SRSF7,G3BP1,RBBP7,MRPS17,NDUFB10,RPL26,USP14,MIR145,MIR16-1,CCNF,EIF4A3,PRKRA,RTRAF,RPS20,VIRMA,NFYB,MIR1-2,RBMS2,GRM2,RPLP0,MIR205,MIRLET7I,MIR34C,MTDH,NPM3,EIF5B,MIR7-3,UTP23,CALR,GRSF1,CD9,MIR34A,HRAS,MIR106B,KRR1,PRR3,MIR25,DCUN1D1,EIF2B2,CDK9,ZBTB2,MRPS23,YTHDF2,MIR15A,APOBEC3D,MIR200C,MIR20A,MIR17,ILF2,RPL23A,THRAP3,MYC,MRPS25,ICAM1,H1-1,VEGFA,CMTR1,MIRLET7B,TRIM29,RPL10,ESR2,PABPC5,MRPL12,ELK4,PIH1D1,RFC4,RAB5A,UFL1,STAU1,IFI16,MIR143,WWP2,RPL6,MIR29C,CPEB1,DDRGK1,MIR31,MIR221,DDX1,MIR140,MAGOH,SRSF1,MIR214,RPS10,MIR9-1,MIR222,HDAC11,RPL31,MIR9-2,ABCF1,PABPC1,CDK5,MIR206,RTCB,CHCHD2,MIR155,RPL7A,RC3H2,UBE2H,RPS3,PSPC1,FGFBP1,RALA,DYRK1A,SRPK2,MIR34B,AGO1,EIF2B3,MIR21,UBE2M,HEXIM1,LUC7L3,MIR7-1,BAP1,MIR10B,RNF113A,MIR107,HSPA5,MIR29A,COX5A,COPS5,E4F1,SNRNP70,RPS2,FZR1,SPPL3,RPS16,CAND1,MIRLET7G,TMPO,MIR429,SURF6,SLAIN2,CDK4,TP53,H2AX,NUPR1,MIR200A,MIR9-3,DHX9,NEDD8,MIRLET7C,MEPCE,H2BC14,RPL17,MIR16-2 |
| 1.504e-14 | -31.83 | RHOG (ras homolog family member G) | protein interactions | 391 | 902 | 357 | 19454 | 5460 |
RPN1,PCDH17,NDUFS6,FAF2,RPL29,IFNGR1,HSDL2,MACO1,DLG3,GOLGA7,FLOT1,AHCYL1,HINT2,HSPD1,SCYL2,PREPL,MAP3K11,HAX1,MRPS26,SLC20A1,MRPL18,RAB32,PIK3R1,PPIA,TMEM237,VAPB,ARMCX3,ELFN2,DAAM1,NOTCH2,TOR1AIP2,STX7,HSCB,CYFIP2,MRPL57,TXNL1,EXD2,SLC7A11,SCFD1,CNIH4,ELMOD2,MRPL16,NIBAN2,PYCR1,PMPCA,PKP4,NDUFAF4,MRPL23,LRRC8A,LAMTOR3,SPCS1,GPR89A,FAM91A1,FAM169A,NDUFS3,MTARC2,TIMM8A,NDUFA2,FASTKD5,ADD2,RAB1A,GARRE1,OSBPL8,POR,HM13,DAG1,GRSF1,LAMTOR2,ATP5MG,MRPL24,MRPS23,MRPL50,PTPN1,HRAS,ACTA2,CTDSP1,STOM,GOLGA5,PICALM,SLC12A2,ST7,COQ8B,RABL3,ARHGAP1,PIP5K1A,SEC22B,CDC42EP4,MRPL20,NF2,YKT6,PDHB,SLC7A1,MRPL17,FBXW7,PIK3R2,SPCS2,RTN4,RPA3,DNAJC19,ARFGAP3,HMOX2,FERMT2,SLC11A2,GAB1,CTNNA1,TUBA1B,NDUFA12,CCR1,PDHA1,TMEM59,NUDCD3,TUBA1A,ETFB,VAMP8,RAB18,KGD4,SLC20A2,ROCK2,CDK5,ARHGAP5,NDUFV2,OLR1,CTNNB1,DDRGK1,DDX50,WWP2,PTDSS1,STX5,CAV2,IL6ST,MRPL12,USP6NL,BET1,ITGAV,ABCC5,LYPLA2,NDUFS2,PHB2,SLCO3A1,H2AZ2,MRPS25,RALGAPA2,STX16,MYC,HNRNPAB,RRAS2,TRMT11,MRPL13,DLST,EXOC3,ATP5PB,PDE12,AKAP12,NEDD8,CLPB,MRPL52,TRMT5,SLITRK5,DHRS7,COX5A,LMAN1,STX6,SLC38A2,VTI1B,SPPL3,FLRT2,ADD1,SLC39A10,SSBP1,MRPS9,ITGA6,LEMD3,CSNK1G3,CYC1,SSR1,CDC42,CLDND1,GRPEL1,NME4,DLAT,GFM1,LRP10,CISD1,MRPS16,ATP1B3,ARHGAP21,GORASP2,SLC25A1,RAB2A,NDUFAF2,ELMO1,PTPMT1,MACROH2A1,NECTIN2,CYB5B,VAMP2,STIM1,MARCKSL1,EMC10,MRPS17,RETREG1,EMC8,ETFA,JAK1,ATG7,WDR11,CLPX,TAF7,MRPS35,STOML2,NDUFS8,CACYBP,RAB11B,SPTAN1,SNX2,GJA1,WDR6,PHB1,NDUFA5,VAV2,ATP5PO,IDH3B,PRDX3,TIMM13,NSFL1C,HADHA,CXCR4,ELMO2,LMNB1,NOA1,TOMM40,CHCHD3,MRPL49,MRPL51,CASK,ZDHHC8,PPIF,MAP1LC3B,LBR,SLC29A1,SMAD1,BCS1L,CCDC47,CTNND1,MRPL22,HSPE1,SNAP23,EMC2,HSD17B10,STX8,NSDHL,DLG1,SLC2A1,ESYT1,TIAM1,RAB23,RELL1,TMEM199,EMC4,DBT,CAV1,ARF6,CDCA3,SRPRA,H2AZ1,EHBP1,JUP,MRPS34,ATG16L1,SNRPN,TMEM209,POLDIP2,B2M,MTDH,ITGA2,MAVS,EPHA2,XPOT,DEPDC1B,PPP1CC,FLRT3,PYCR2,SH3BP4,YES1,SLC25A4,ACAT1,VAMP3,STBD1,CHCHD2,EFNB1,SEC11A,TMEM87A,RINT1,MRPL9,PPFIBP1,TBC1D5,VAMP7,PNPLA8,MRPS18A,PAK2,UBAC2,YIPF5,NDUFAF3,GOSR2,GNB4,MRPS7,EMC1,RER1,OXCT1,MRPL34,AKAP1,SLC38A1,SPCS3,LAMTOR1,ATP6AP2,ATP5F1B,FAM83B,TACO1,TFRC,BMPR2,HADH,UBIAD1,SNAP29,PREB,MRPL47,SLC6A8,FKBP8,SRPRB,MRPS18B,ABCE1,STX18,PALM2AKAP2,SLC25A11,SMAD4,TMPO,FCHO2,CAMLG,GIT2,ACACA,RPA2,CD46,QRSL1,IDH2,SPTBN1,TOMM20,MRPL41,MRPL40,TWNK,RAB9A,ATP1A1,SLC6A6,RSPH1,C9orf72,ROCK1,CCR2,MRPS28,STX10 |
| 1.517e-14 | -31.82 | ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1) | protein interactions | 476 | 533 | 231 | 19454 | 5460 |
ATP5MG,ATP1B1,LAMP3,HDAC6,MUL1,STYK1,RCHY1,HRAS,AIFM1,PTPN1,HSD17B11,PRNP,ARF6,ZBTB2,CAV1,G6PD,CDK9,FBP1,CCDC47,SFXN1,TCOF1,RAB1A,EMC2,PC,HUWE1,RIGI,FBXO25,CSK,FBXO7,ATP5F1A,TXNIP,CCNF,VAMP3,RHOJ,COPE,VIRMA,UQCRQ,TECR,TPT1,PSMC4,UQCRC1,GRM2,HSP90B1,ZNF574,HNRNPH3,SIRT7,NCDN,RHOU,RPA3,SOD1,SQSTM1,RTN4,BRIX1,MARCHF5,PSMD3,SLC25A28,RHOG,RPL23,AHSA1,PSMB5,PHB1,ATP6V1A,GJA1,NOP58,DHX15,EGLN3,DIRAS3,E2F4,B3GNT2,RAF1,LGR4,PPP2R1A,FAF2,GDI2,RPN1,EZH2,SART3,CYB5B,TMT1A,SLC25A5,HSPD1,ZYX,COX8A,MRPS11,UBE3A,CDK20,G3BP1,LASP1,AHCYL1,RPS27A,PSMD12,RAB11A,CUL3,TOMM40,YWHAZ,RHOB,ATP1A3,RIT1,ILK,HSP90AA1,SEC61B,LGALS3,TUBB,RND2,ARMCX3,KLF3,SLC25A3,EXD2,CCDC86,HADHA,PMAIP1,G3BP2,PSMC1,STX7,COIL,FAM20C,DPP4,TPM3,CD81,H2AC4,CD274,COQ8A,RAC2,ADD1,TMPO,LMAN1,MTCH2,TP53,ZNRF1,PSMC3,FURIN,ATP2B4,DHX9,RAB3B,TOLLIP,NUP107,SMARCA5,RAB2A,AKT1,SLC25A1,CFL1,ATP1B3,UBE2H,ATP1A1,PSMA6,RPS3,UQCRC2,MACROH2A1,PSMC5,KCTD9,SRC,CFTR,CDC42,GABRA1,GPR35,RPA2,CYC1,UBE2M,PRKCA,HEXIM1,UGDH,BAP1,DERL1,PRDX6,RAB9A,RNF113A,MRPL40,HSPA5,RAB5C,MAPK4,LAMP2,DDRGK1,FAM241A,CTNNB1,AGR2,NDUFB8,RAB35,SSR2,RHOH,TCP1,RAB1B,CCT7,MSX2,RPS7,EEF2,NCSTN,ISG15,SNAPIN,PDHA1,HGS,RND3,PABPC1,CCT8,MYO1B,RUVBL1,VDAC1,PSMA1,KRAS,PSMA4,MYC,LAMTOR1,CCT2,LMBR1L,VDAC2,GPNMB,FBXO22,STAT1,MATR3,ESR2,FBXO42,CLDN4,TOMM22,SEC62,YIPF5,PPT1,ADSS2,CSNK1A1,PIH1D1,XRCC5,PEBP1,RAB5A,AKAP1,HDAC5,SF3B1,PDSS2,HSPA8,ADRB2,STAU1,EMC1,UFL1,NDUFS2 |
| 1.564e-14 | -31.79 | negative regulation of response to stimulus | biological process | GO:0048585 | 1760 | 660 | 18204 | 5365 |
OPRL1,DRD1,PIH1D1,TERT,MIR16-1,NFKB1,MIR141,ARG2,PDE2A,NUP62,SOSTDC1,MAPKAPK5,CCL2,DUSP6,NHERF1,IL2RA,PPIF,RNF26,TRIB1,TBK1,CYRIB,CSNK1A1L,DPP4,FKTN,SLC12A2,MIR222,MIR373,CLEC12B,DUSP9,CTNND1,THBD,CD2AP,DDIT4L,LACRT,DUSP1,YES1,KBTBD6,EGFL7,MIR920,PDCD1,TAF9,CRHBP,TRIM32,CCN3,SCYL2,DUSP22,SMAD3,CERS2,KCTD10,MIR24-1,MIR101-1,SARM1,LMBR1L,NT5C2,CCAR2,ADIPOR1,PSMA1,STK38,STAP1,STK11,CREB3,HDAC6,NOG,FCGR2B,PRR5L,ATF3,NFKBIL1,FBXW7,NKX3-1,MINAR1,TMBIM6,OTULIN,CISH,TXNDC12,BFAR,SYK,CLU,MIR205,LPXN,MIR874,UBASH3B,NF2,MIR29A,RNF115,SAMHD1,RGS6,IVNS1ABP,CARD19,PPM1B,MIR181C,PRELID1,NFE2L2,FBXO7,BPIFB1,CTNNBIP1,CCDC3,LMO3,TFIP11,NIBAN2,IFI16,MIR218-1,YWHAZ,PRKACB,BRMS1,PIK3R2,CUL3,NR0B1,MIR100,MIR15A,LGR4,NEO1,TRIM45,PDCD4,TCIM,RGS7BP,ICAM1,MIR873,MIR34B,PAFAH1B1,LEP,SQSTM1,TNFAIP8L1,INSIG2,THY1,WIF1,ATF4,PDE4B,CD200,TRIM21,MIR140,BACE1,FGL2,PHB2,TFPI,PSMB4,SRC,SH3BP4,MIR34C,CDK20,DAG1,PBLD,RB1CC1,MMP28,FAIM,GTF2H2,SMCHD1,PARL,RGMA,DEFB114,GSK3A,CRY1,TMEM88,SYVN1,CDK5RAP3,TSPAN15,RPGRIP1L,MIR187,NRP1,STAT1,ACP5,NR1H2,MIR573,MIR125A,TSG101,PTEN,BCL2L1,NCOA5,RRN3,MIR497,AR,UBE2D1,KLRD1,SOD1,UBE2N,CARTPT,MIRLET7B,IL2,MIR130A,MIR221,ARRDC3,CAAP1,PID1,IL22,GNAI2,MIR206,HTRA1,MET,DLK2,CD59,XBP1,AATF,ADRB3,GPX1,KICS2,INPP5E,GSTP1,HYAL2,SHLD1,BAK1,RGS5,CTNNB1,RBBP4,TNFAIP3,SIRT7,BOK,CALR,TAX1BP3,SPRED1,UCP2,CNOT2,VDAC2,UBE2W,ENY2,SNX5,NFKBIA,SAP30,IGF1,SELENOS,GRB10,SMAD4,TANK,SDHAF2,DRD3,GPC1,SLC25A31,TLR6,MIR92B,MIR99A,DUSP26,RADX,SIAH2,TGFB3,IL1B,NOP53,MIOS,AKT1,HERC4,PPP3CA,MIR1271,ZMYND11,LMNA,TCF21,HHIP,NDUFS3,ZNF592,RMI2,SLC35C1,TPT1,CD80,MIR129-1,UCN,VPS18,OPTN,MIR210,NMI,MIR204,SAR1B,SERPINB9,SIN3A,LYAR,MAD2L2,PPP1R10,MIR519D,MIR21,IFNA2,LPCAT3,CD9,SFN,AQP11,CPNE1,LILRA2,MIR375,SH2D1A,MCL1,PROS1,UBE2B,HACD3,PEBP1,SMURF1,HDAC3,RGS10,TNFRSF1B,LEPROTL1,TLR9,PADI2,ACAA2,PYDC2,MIR107,MMP9,CSK,IL6,BAX,STAMBP,USP38,MOSMO,UBE3A,IL12B,MMP14,FGR,ELF1,BRAP,MIR185,PEA15,MIR223,YWHAG,FOXP1,MACIR,GPR37L1,PAK5,TMBIM1,PPARA,MIR449A,PRNP,SPRY1,TMEM196,MIR885,ERRFI1,MIR1224,FAM89B,FOXP3,LDLR,ENO1,PPP2CB,MIR186,OGG1,SLC25A5,NLRP2,NPY5R,STRADB,GREM2,RB1,CTTN,CITED1,TBC1D10C,CGAS,TNFAIP1,MIR424,GGT7,RNF152,NKIRAS2,EID2,MDFI,MIR105-1,HAPSTR1,TMSB4X,TNFRSF14,INPPL1,PSMD10,RHOH,IRF4,F2,CCR2,AIF1,MIRLET7C,CLDN3,PIP4K2C,ACVR1,EIF4E2,CASTOR2,NLRP3,MIR214,MIR17,YWHAB,ING1,RPS3,PHB1,MIR145,CX3CR1,SLC25A4,SEC13,IL10,NDUFAF2,XCL1,MUL1,RAF1,MIR1298,CX3CL1,BRMS1L,RBBP7,LBH,TNF,ADIPOQ,DDRGK1,TWSG1,DUSP10,CHRDL1,MIR23A,PYCARD,PLG,MIR361,HECW1,FBP1,TBC1D24,MIR98,EMILIN1,ARHGAP12,RGS2,MPIG6B,PFDN5,CTDSPL2,HFE,EPHA2,CXCL12,BCL6,ABHD17A,STUB1,FEM1A,DDAH1,MIR495,EZH2,IL7,MIRLET7G,PYCR1,FZD6,MIR195,LEMD3,YTHDF2,CNOT7,TRIM15,MKKS,EGR1,C1QTNF1,TPBG,EPO,NR4A2,LGALS3,SGTA,SFRP4,PAQR3,PTGER4,CCDC22,CSNK1A1,PPARG,MIR503,UFL1,CXCL13,SUFU,HOMER3,PPP2R1A,MIR106A,TNFAIP8L2,SESN2,PRKCQ,SLA2,UFD1,HELLS,UBE2D3,IL13,MIR34A,SOD2,AZI2,MIR1-1,SOST,SYNJ2BP,ITGA6,TNFAIP6,ZNF451,TP53,ST6GAL1,STK4,RGS1,LPAR1,CXCL8,MDM2,MIR133B,CER1,DDIT3,TRIM27,EYA3,DHRS3,IFI6,TLR4,APLNR,GHITM,SEC14L1,JADE1,NONO,MIR590,MICB,TMEM14A,KLF4,HSPA8,ADORA1,NKIRAS1,PTPN1,MIR26B,PCGF2,PRDX2,ACKR3,ITGAV,MIR340,OAS1,IGFBP4,RNF126,MIR488,HGS,PRKCB,SAP30L,MIR708,TMEM170B,CAV2,KDM1A,USP14,H2BC11,MIR29C,NLRP6,FKBP1A,CD200R1,ATP2B4,MIR200C,DLG1,CHST11,IGBP1,SLC35F6,LITAF,BANF1,DNAJB9,DICER1,IFI35,SNAI2,NDFIP1,CBL,STAT2,SOX9,CTNNA2,ANKRD6,TNR,FAM3A,CTNNA1,CSNK2A1,GHRL,MIR20A,ARHGAP25,IL1R2,MIR9-1,NCK1,JAGN1,OTUD7B,SPRED2,SHISA2,TLE1,SESN3,FGF10,KLHL15,CRYBA1,MAP2K3,DUSP3,IL1A,TGFB2,CHP1,SLC6A3,PAK1IP1,SVIP,ADRB2,GREM1,RNF167,ADTRP,MIR152,DDIT4,STAT6,ISG15,SEMA5A,MIR25,SPP1,DYRK1A,DKK1,TRAFD1,COL3A1,PTPN22,SOX2,GCLC,DKK3,RUVBL2,MSTN,CAV3,ING2,LYPLAL1,TAX1BP1,FKBP1B,MAD2L1BP,CDKN2D,VGLL4,RC3H2,FURIN,MAVS,TRIM11,IFNB1,CAV1,CPTP,SOCS3,LILRB4,MIR146A,PSEN1,MTM1,TULP3,RNF113A,IGFBP3,MIR149,FXN,CD46,MIR31,BRCA1,IL4,MIR342,HSPA5,IL20RB,SOCS5,CNKSR3,LDLRAD4,HTRA2,TMEM127,BEND6,MIR142,DUSP19,SOCS2,HSPB1,MIR490,GPR17,PPIA,SFRP1,MIR302B,FLCN,IGF1R,FRMD8,MIR126,IER3,CSNK1E,IFT172,MYC,UBAC2,LRRC14,DLX1,WWP2,DYRK2,EPHA4,PEG10,G3BP1,RGS19,CCL5,CASK,STK3,RNF34,HEY2,USP15,CSF2,SOCS4,SMAD5,BTN2A2,LILRB1,SNIP1,PELI3,APLN,SCG2,IL12A,INPP5K,DDT,MIR132,MIF,CYP26A1,FRZB |
| 1.574e-14 | -31.78 | RPS27 (ribosomal protein S27) | protein interactions | 6232 | 307 | 149 | 19454 | 5460 |
EEF1A1,RPL15,UBL4A,RPSA,TP53,MTCH2,SRP72,PIK3CA,DNAJC2,ABCE1,RPL23A,RPL3,IGF1R,MAP1B,RPS13,POLE4,MEPCE,MRPS18C,RBCK1,VRK1,TOLLIP,TOM1,COPS5,HDAC6,RPS2,RPL10A,SNRNP70,RPL24,WDCP,RPL12,RBM42,CDK9,MDM2,ZBTB2,FZR1,CAND1,RPS16,RPL35A,RPS27L,CDC42,ATG16L1,RPS14,UBE2M,HEXIM1,RPLP0,RPA2,METTL14,GRM2,RTN4,RNF113A,BAP1,RPL27,RPA3,PNO1,HSPA5,MARS1,RPS15,RPL4,FBXW7,FBXO7,RPS17,RPL7A,ZBTB38,UBE2H,RC3H2,PRSS8,GSK3A,RPS12,PPP2R5E,RPS20,PTEN,RPS3,CCNF,METAP2,RPL22,SRC,RPL13A,TUBA1A,ACTN4,RPS7,B3GNT2,RPS11,POLR2C,RPL18,RPS23,EZH2,PDHA1,CHMP4C,RUVBL2,RPS24,RPL31,RPS4X,IMMP2L,TNF,KRAS,YWHAG,YWHAH,DDRGK1,EIF3D,MAP3K14,CTNNB1,ATG9A,RPL6,WWP2,PEX3,DRG1,RPL23,AGR2,RPLP2,RPL9,RPL8,DUSP6,PHB1,RPS10,RPL7,RPL27A,PIH1D1,HSPA8,RAB5A,PYM1,RPS28,COIL,ASB3,G3BP2,HNRNPA0,UFL1,STAU1,BTF3,MYC,ENTPD4,RAB11A,CUL2,CUL3,RPS5,RPS26,RIT1,ATG3,DCAF4,BRCA1,RPS9,SEC61B,FAU,NFKBIA,MAD2L2,RPL19,RPL10,ACTB,TUBB,RPL35 |
| 1.704e-14 | -31.70 | positive regulation of biological process | biological process | GO:0048518 | 6326 | 2088 | 18204 | 5365 |
SEMA7A,TFE3,SLC38A1,SOX3,FBXO7,NFE2L2,AKR1C2,COX17,MPV17L2,SMARCB1,SLITRK1,BMPR1A,CCDC3,TOMM7,BORCS5,MIR296,TLR8,NTRK3,ZNF319,EIF2B5,RFXANK,MIR100,MIR625,GSTO1,BRMS1,TRIM3,STK16,RAB8B,DYNLL1,RNF146,ARHGAP5,MIR34B,DOK5,MED17,SERINC3,PHB2,ZNF175,CBLL1,SQSTM1,LEP,POLR2G,WIF1,TM9SF4,EPS8,CD200,FAM162A,NME1,TNFSF12,KCNJ11,SMARCA5,SH3BP4,CALY,DAG1,STAC3,TERT,MIR491,CRADD,MIR141,EIF2S1,FUT9,IL15RA,SRI,GNA11,FGF13,ALOX5AP,UBXN2B,PABPC1,DISC1,HCLS1,TFCP2,TASL,BMPR1B,PML,SFTPD,TLR5,GRM2,C2CD2L,CTLA4,NINJ1,GSKIP,NEK2,CD2AP,CD38,LAMTOR1,NDP,TLR10,FXR2,MARCKSL1,GADD45A,SLITRK2,PIK3AP1,RAP1A,TUSC2,TFRC,CLTRN,ALKAL1,PCBD1,STC1,CRTC2,RPS7,PKNOX1,NKX3-1,ADIPOR1,CLU,MED30,OTULIN,CCL23,TMEM164,MACROH2A2,CD36,RBBP9,PMAIP1,BAP1,IREB2,DXO,TCF21,FOXD3,MED29,TTC23,ANAPC2,ELP6,DHRS4,CPNE1,RPS2,ECD,CACNG3,FGFBP1,MIR21,SMURF1,EMP2,MOB3C,DNM2,NOS1AP,PCK2,CD99L2,CREBL2,UBE2B,GLIPR2,HACD3,JAK1,ELAPOR2,GPRASP3,SYNCRIP,CSK,ABHD6,RFX5,SLITRK5,GTF2F1,STAMBP,SPG21,ERP29,BTG1,ZNF267,THRAP3,LDB2,RNASEL,FGR,NEUROD2,ZNF263,ADRB1,GRM1,MIR10A,TRAF7,VEGFC,RXRG,IFNGR1,PELI1,PPARA,NCKIPSD,HAS3,PRL,CD79B,TRIM34,MIR186,JUNB,OTX2,DMAP1,TRPC1,ENO1,AURKAIP1,LDLR,CRY1,LACC1,L1CAM,TEX261,DVL2,CD34,SMCHD1,RAB27A,DEFB114,SLC4A8,LMO2,APOC4,PTEN,JAK2,MORF4L1,MED31,LRP6,STAT1,VLDLR,TTI2,STX7,IRAK1BP1,CAND1,ATP5IF1,MIR221,PSMC3,SS18,UBE2M,RRN3,MIR497,UBE2N,CARTPT,SLC8A1,LMO4,GRIA1,RIOK2,CDC42EP2,TNFSF13,CREBZF,GNAI2,RLN2,CD14,EIF2AK2,HYAL2,SHLD1,MIR95,SLC1A1,CTNNB1,RALA,CYFIP2,GPT,KLK5,TTL,PDCD10,SNX5,CERS6,PACSIN3,KARS1,EIF3D,NAA16,RNF128,SMAD4,INO80E,SEMA3C,UBE2V1,CALHM2,NDNF,NOP53,TNFSF15,NFYB,MIRLET7G,NCSTN,RPS20,YTHDF2,EZH2,IL3,UPF3B,CHRNA7,ADCK1,EPO,MNAT1,NR4A2,MIR28,MKKS,IL34,IKBKB,CHCHD4,EGR1,CLSTN3,PPARG,SRARP,MIR30A,CCDC22,F11R,COP1,MIR193A,GAB1,HECTD1,PGR,FAXDC2,ZNHIT1,SESN2,MIR106A,SLA2,PRKCQ,ITGA6,SCN1B,UBE2D3,ATG101,UBP1,RRAGA,CXCL8,LPAR1,CCNY,MIR133B,CTSC,FKBP8,TMEM30A,RRAS2,ERCC3,CCL8,MIR590,TOMM70,DDIT3,EYA3,DNAJC2,PSENEN,RAC2,PRDX2,TSHR,NKAP,MIR340,SRSF1,PLPP4,P2RY1,AAMDC,ADORA1,SIX5,FGF22,TRA2B,ASIC2,STRADB,ADNP,CTTN,DAP,VIPR1,CGAS,DCUN1D1,ZNF593,VAMP2,RELL1,USP16,ELOVL6,RFC4,SH3GLB1,F2,CCR2,EDEM2,PPIH,POMT2,PIP4K2C,TMEM126A,CAPN1,BCL7C,PLSCR1,LMAN1,PRKCA,BRD3,NEFL,TBC1D5,ACVR1,CD1C,AZIN2,DBH,MIR145,CX3CR1,MSX1,RFC5,NKX6-2,LY96,RAB11A,VAMP7,NAA15,RBBP7,CRLF3,POLDIP3,DDRGK1,MAP3K11,STN1,PTGFR,MIR640,IL10,ARMCX3,SLC39A10,RAF1,CACNB3,TRIM46,GABPA,CXCR4,GTPBP1,TMEM198,CD226,PYCARD,HRAS,LRRC24,ABHD17A,ZDHHC8,MBL2,FEM1A,KCTD11,DFFA,HMGB1,MAPRE2,BCL7B,CD1D,RGS2,SSBP4,PTK7,KLK6,VPS28,PNMA3,RAB1A,AGAP2,NDUFA4,CNPY4,BLOC1S3,PIM2,ODC1,SUPT7L,CAV1,IFNB1,MCOLN1,SOCS3,MEPCE,MEAF6,TNKS,TAB1,CLDN1,IDE,SNRNP70,MIR324,FAM83B,UBE2I,APOBEC3F,MTM1,PSEN1,TNKS2,PTN,CD4,IRF9,RBM22,MIR31,BUD31,SLC38A3,BRCA1,ALKBH5,SMAD2,MIR342,MIR126,ZER1,ATP1B3,MYC,MIR142,MARS1,HSPB1,SEMA6C,CDC20,DAPK1,FITM2,GPSM3,MIR106B,CASK,DLX1,HCRT,SSBP2,RIMS3,SOS2,GLRA1,NFIL3,MED21,MTCH2,TNFSF8,PDCD5,KCNJ2,OSR2,RPS6KA4,SSBP1,ATP6AP2,CDK1,DDT,FOSL2,LTA,OAS1,SETD3,TWIST2,RNF126,HNRNPC,COPS5,CLRN1,SUMO1,CDCA7L,IRF7,CD151,RER1,NLRP6,SMAD1,CHRM1,MIR200C,CCT2,CAV2,RETREG3,ACTN4,MIR1260B,ADAMTS20,HSPE1,SLC35F6,LITAF,PICALM,ATP1A2,PYM1,TRIM22,AIP,FEN1,MTF1,FGF10,NCK1,IRF6,IL2RG,CPT2,TF,ADAMTS1,DPY30,KRAS,MBD5,IL1A,KLK3,WASF3,ZBTB18,PROX1,CREBBP,TNFSF18,JCHAIN,CCL20,WASL,GCLC,DYRK1A,GSTM2,SLC38A2,PRRT1,CCAR1,LAMTOR2,NF2,MIR769,IL15,MIR137,TLR1,RPS12,HSPB6,BCL9,LLPH,FABP5,ADIG,NIBAN2,STIM1,OPRK1,ELK4,TCP1,TRUB1,STOM,CCNB1,SETD4,CUL3,NR2E1,PIK3R1,RAN,ZNRF1,STAU1,NEO1,SURF4,CACUL1,PDCD4,ETV6,MIR143,CAMP,TIAM1,PAFAH1B1,NLE1,CDC23,SCHIP1,FASLG,REG1B,PIK3CG,HNRNPA2B1,NECTIN2,IL18,NEGR1,TRIM35,UQCC2,TAS1R2,WRAP53,ELK3,PIH1D1,DRD1,RDH10,CACNB4,MIR16-1,CHRM3,DCUN1D3,SYNGR3,IL2RA,NHERF1,MAP2K6,WBP2,NUP62,MAPKAPK5,FAM161A,AKAP8L,PICK1,RNF10,EEIG1,PTHLH,STAT5A,VIP,CDC42EP3,MRPL12,CYP1B1,TLR2,MIR183,VMP1,PDCD1,TNRC6C,STAR,EGLN3,LACRT,YES1,BIRC2,SLC23A2,EGFL7,PRKAB1,SPTBN1,NIF3L1,CD2,ATRAID,PARP2,WEE2,PRSS8,SCN3B,TCEA1,SGF29,HDAC6,RGL2,NME2,FOXA3,POLDIP2,CCAR2,MED22,ALKBH4,TMED9,STK11,CREB3,NR1I3,PSMC1,ARFGEF1,CD40,MED10,ACVR1B,DERL2,SAV1,CD80,GABPB1,UCN,LPAR2,NCAPG2,GTF2A1,MNS1,MED27,SSBP3,GPR65,MAD2L2,EDNRA,FOXS1,NMI,DSTYK,CLEC6A,MIR204,MIR423,SELENON,DNAJC3,PPP1R10,FABP4,MEF2B,CDC73,DNAJB2,LPCAT3,IFNA2,MLLT6,ADM2,TNFRSF1B,PLCB1,TLR9,MCL1,PPP2R5A,MGST2,AGPAT1,TOM1L1,IL6,EFCAB7,MOB3B,MIR379,BAX,TRAF3IP2,ENPP4,GP9,SOX21,ADIPOR2,IFNA10,PAIP1,MMP9,CD86,DNAJC27,MIR223,G3BP2,ACVR1C,ACSL4,GPM6B,FCER1G,DDX1,SLC7A1,ELF1,IQSEC1,SF3B4,BVES,PRNP,MIR130B,OXSR1,DAPK3,OR2AT4,EMC10,TMBIM1,GPR137,SLX1A,GNG5,PLXNC1,AKT2,FUT1,MATR3,DHPS,FAM89B,UHMK1,ACER3,EGLN2,CDK5RAP3,ROGDI,MIR448,TSG101,PPP5C,E4F1,TFG,PLA2G5,NR1H2,TGFBR2,UBE2D1,RND2,HNRNPAB,KLRD1,MET,TOLLIP,MIR320A,TSPAN5,ANP32B,FLRT3,KIT,FAS,GID8,GSTP1,MAX,TXN,GH1,TNFAIP3,RBBP4,RETN,TOX,CCND3,NEUROD6,MT3,CREB3L4,UCP2,ENY2,CNOT2,ROMO1,DKC1,PTRH2,IGF1,HMX2,APH1A,NSG1,CALR,GRSF1,MIR675,ABCB1,TLR6,AGR2,EXOSC8,IFNA13,SLCO3A1,PFKFB2,MIR211,PPP3CA,FAM107A,SLC6A1,MIR182,ELAVL4,SLC45A3,RANBP1,IL1B,DYRK1B,AKT1,B2M,GTF2I,PRIM2,EIF2B2,LHX2,ATAT1,C1QTNF1,HMCES,HINT1,ZNF668,LUM,S100B,RNF139,SIA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4H1,GPIHBP1,LYPD6,P2RY12,ROCK1,MIR15A,SYT2,F7,IL17F,TAF10,CD47,PIK3CA,CACNB2,ELOVL3,NTF4,NLGN1,APEX1,TCIM,ZC4H2,ICAM1,BACE1,UTP25,CD58,CD40LG,RNF41,STX18,MIR939,THY1,MIR140,TFEB,PDE4B,RB1CC1,CSH1,LAMTOR3,SERPINI1,OLFM2,ASB11,SERTAD3,SEMG2,PHF23,PSMC5,CLEC9A,CHCHD2,CCL2,DUSP6,NPSR1,IGF2BP1,NPPC,PDE2A,POU1F1,JMJD8,ARL2BP,PIAS1,DIRAS1,VAMP3,DPP4,TMEM97,CDK4,FEZ1,XRCC5,TBK1,CYRIB,APOBEC3A,ZNF287,CD1B,SLC12A2,RAB5A,MIR373,RARRES2,G6PD,MYLIP,TMOD3,MAGEA4,MED9,CYB5D2,TRMT112,GPAM,UBE2L3,TRIM32,CNOT6L,PSMC4,SERTAD1,MED23,LAMP3,VSIR,APBB3,DCUN1D5,MIR101-1,ZDHHC17,EAF2,PRR5L,TESC,NOG,S100A8,PRDX6,FBXW7,SELENOT,TRIM5,APOBEC3C,PROM1,CCR4,NLRP1,HILPDA,SYK,FGF16,PITHD1,BOLL,BABAM1,CDC42EP4,OPTN,CASP12,PRKAG1,NUS1,TP53INP2,RIGI,PAX6,TPPP2,SMYD3,WNT10B,TXNIP,SAR1B,LCP2,SYT4,SFN,SEMA4C,EHD4,AQP11,NACC2,UBE2S,TNIK,ZNF507,MIR96,HDAC3,SMARCD3,ATG7,IFNK,OCIAD2,SH2D1A,ZNF24,ZBTB16,NDST1,AHCYL1,ID4,HAPLN2,EIF4E,TP53INP1,PADI2,GADD45G,MIEF1,ASPM,PTP4A3,TMEM100,ZNF513,LRRTM1,POLD4,MAGEC2,MMP14,UBE2K,E2F4,CLIP3,PAFAH1B2,HAX1,SPRY1,KLHL25,TENT4A,SMARCE1,PPP1R12A,ACTL6A,MIR1224,FOXP3,CD274,CA2,AKT3,GLCE,PRKCE,DIO2,ATF1,LCP1,MIR10B,RGMA,TAF11,PPP3R2,CCL28,PCSK9,NRP1,B4GALT1,MIR125A,FGF1,IL2,MIRLET7B,CYTL1,PAK2,MIR130A,CCND1,CNR1,LAT2,AR,SOD1,XBP1,PID1,BAK1,MAP1B,VDR,TCAF2,RAB3D,OXTR,CXCL11,TEF,BRD9,DIO3,SPRED1,LPAR6,CIBAR1,SAP30,NFKBIA,SIRT7,ASPA,GRPR,SNX18,TCF23,FUBP3,TMED4,RPS4X,DUSP26,NCR3,SERTAD2,GPC1,ITGA2,CCT7,RPL26,WNT7A,NPY,VSTM2A,CEBPE,TGFB3,BMP1,AIFM1,FAF1,MIR195,DROSHA,HEXB,MIR198,KPNA2,LGALS3,DET1,TRIM15,CYP27B1,GPM6A,RBM3,UFL1,CXCL13,CD247,PSME2,TRIM52,CDKN1B,MLC1,TRA2A,S100A6,FOXJ3,MIR1-1,HPCA,KIF3B,SSR1,DDX5,NCBP2,FADS2,MIR188,MDM2,SDCBP,TP53,PAX9,CRBN,ST3GAL4,ARHGEF39,DLG4,JADE1,ZNF473,ACKR3,TMEM33,HSPA8,CSRNP3,PPIB,BAG2,PTPN1,TAFAZZIN,CCL18,RNF152,ILK,CASP4,NPY5R,NLRP2,MIR301A,ZNF365,GPR89A,TNFAIP1,LSM14A,MED4,SUPT5H,TENT5C,CDKN1A,LRAT,IRF4,ARF6,CLDN3,TENM3,PDCD1LG2,CSNK2B,MIR214,ZBED4,ZHX3,TPPP3,CCL25,NLRP3,FCGR2A,TESPA1,ING1,PHB1,MID1IP1,VAPB,CAMK2N1,PPT1,MUL1,NGRN,CX3CL1,MIR98,DUSP10,GTF2A2,CCT8,RANGRF,STUB1,FGF7,GOLPH3L,PNMA2,KCNMA1,CDK5,CLDN4,CXCL12,PLAC8,CMA1,TADA1,SWAP70,USP5,RUVBL2,AP2M1,ING2,EFNA5,MIR150,LANCL2,GPR35,GPBP1L1,CSNK1G3,FAM98A,FXN,CBLN2,DGCR8,NKRF,MIR146A,MDC1,GADD45B,IL4,ILF2,TACR1,FLCN,CCL17,SOCS2,DUSP19,NUPR1,AGO1,FZR1,FCHSD2,CCL5,KCNB1,RORB,CDC16,AKAP12,DYRK2,TRIM68,TLR3,IRF3,MAP3K12,HEY2,KLF12,STK3,CFL1,PARD6A,OPRM1,SETD7,RNF34,HNF1B,MIF,RAB9A,RWDD3,EIF5A2,IL12A,MIR132,BCL10,IRF8,CCR1,SAP30L,DRG1,REG1A,NUCKS1,FKBP1A,PRPF19,DNPH1,PELO,ING5,NR1I2,ANAPC11,DHX15,CDC5L,LTBR,EFNB1,SNAI2,RAB3A,RBM23,MVD,DLG3,CYP1A1,BRINP3,CSNK2A1,PROK1,HNRNPA0,GHRL,AZIN1,HOXC4,PAEP,NDFIP1,CBL,RHEB,SOX9,BAG3,RERE,ADD1,PAOX,SESN3,MIR9-1,SCAND1,RPRD1B,CD209,PARM1,LRP3,MIR192,ZFAND2A,MAP2K3,DUSP3,CCR7,RNF8,STAT6,SEMA5A,ADRB2,C9orf72,PRDM4,HAND2,CFAP20,MBD3,RAB3B,RFC2,GAS8,PKP4,HOXB1,DKK1,RAB1B,VAMP8 |
| 1.893e-14 | -31.60 | binding | molecular function | GO:0005488 | 16422 | 5043 | 18094 | 5411 |
LTB,ARMC1,SLC25A20,RHOH,TACO1,REEP6,ZBED3,SLC6A4,MFAP1,STAMBPL1,POLB,EGLN3,PPP2CB,CCL2,CFAP298,CCDC32,HSP90B1,CTNNBL1,KRT7,ACSS2,AKAP1,TGFB3,CRABP2,SAP30BP,CA8,SUPT4H1,NOA1,JAK1,SLC16A10,WDR45,GNG11,LIX1,TMEM31,SS18,GNMT,ZNF688,ACTB,RPL7A,GJB1,USP30,MRPL13,SNAPC3,RUNX1,HINT1,ETNK2,MIR183,CDK4,GREM2,APH1A,LACRT,ANAPC15,MIR491,MRPS28,JAKMIP2,RAB35,PPIL4,ATRAID,RGS5,FAM221A,CCL8,KMT5B,LHB,UBE2D1,CAVIN2,CCR5,THAP1,TPD52,MOSPD1,PLA2G4B,UTP6,HSPB6,CHCHD6,TM9SF4,IMPA2,CDC40,NKRF,PRDX2,DKK1,ZNF451,ZBTB14,BOLL,PDIA6,STBD1,SDC4,HDDC2,GOLPH3L,TSPAN17,LSM10,BAG2,MORC2,RPL8,POLE4,SLC13A5,TOX,RHBDL3,MIR96,EIF2B3,PELI3,SPATA25,FOLR2,SESN3,HELLS,ZNF397,SLC6A2,ACVR1,HNRNPF,TRIM24,APEX1,POU3F4,PSMB10,H1-3,ARL11,SLA2,EXOC2,CLEC12B,RGP1,RPAIN,CFAP68,PARL,MPHOSPH10,OCRL,TSN,RNF115,NCKIPSD,MIR125A,CD2BP2,MTMR12,TAS2R16,TIMP3,SNRNP27,CCDC92,TRIM36,FIG4,GRAP,TLR10,TFDP2,PEBP1,HMCES,APEX2,DNTT,RPS15,HIKESHI,CAMP,HPCAL1,RASL10A,CXCL1,HEY2,CACNB4,FLYWCH2,PLEKHJ1,POU1F1,LHX2,SNX20,DNAJC30,GALNT12,EXTL2,MCM6,DCTN3,CDKN2D,UTP23,GPN2,TMEM182,ATP5PF,VPS33A,POLD4,LANCL2,FLRT3,XCL1,DROSHA,RALB,LEP,PROM1,SELENON,FTSJ3,REP15,NAP1L3,SUB1,FZD4,BRMS1,PAQR9,MIR99B,WDR11,APEH,EMG1,SEMA3C,AANAT,CERS2,CCDC106,YPEL5,GSTO1,CDCA7L,RNF128,DIRAS2,RANBP6,LIG3,NDUFA5,ADM2,LEMD3,RBCK1,TMEM115,SEC61A1,ANAPC4,RASD1,ITGAV,IKZF2,SSBP4,MAK16,ATXN1L,HSD17B1,GNA14,RETREG3,MINAR1,GNPNAT1,TMEM50B,RNF148,TLE1,TXNL4A,PNO1,G2E3,CCL27,DLG4,VPS54,MMAA,SPCS1,RSAD2,H2AB1,MIR15A,HTRA2,RERG,UTS2,TNFAIP8L1,SMC4,HUWE1,SNRPD1,ARHGEF6,TMEM123,PTPN4,TMEM19,OS9,BRD9,GLRA2,FKBP2,NPB,PGS1,FAM98A,SNRPA1,UNC50,HILPDA,ZSCAN25,APOC4,PPP2R5A,SETD3,SLC35A5,CCIN,CRHR1,CCNQ,TYMS,HSCB,LYAR,GEMIN7,NUDCD3,ACTL6B,JUN,ARL6IP5,TMEM220,LECT2,CALHM3,RNASE1,HMG20A,MTX2,ITGA6,SMCHD1,TNKS2,TRNP1,TBC1D1,PIGY,CAMK2N1,MIR150,RNF167,FOXS1,CCM2,DCTD,PSMD7,MMP20,PCDHB13,STX6,NLRP2,EPCAM,MAEA,CALR,RPA3,KDM1A,SOX14,SSR1,HSD11B1,DOLK,TSPAN10,SPP1,CCDC65,STAC3,ELAVL4,TPPP2,CDKN1B,KDELR1,NDUFB10,MTA3,FEZ1,CLDN1,BOLA1,KCNJ10,NLRP6,RWDD3,SDHB,FUBP3,FOXJ3,EPHA2,IL12A,RBM12,CDC23,NKIRAS2,NCK1,TMEM248,FHOD3,MIR429,PIH1D1,CHMP4C,CLEC6A,VASH1,SCML2,LSM12,H1-10,KLHL24,COPS5,KLHL7,CYP17A1,MBD5,SIVA1,USP6NL,BCKDK,CYP3A43,UQCC2,EMILIN1,OR5I1,IL7,POLDIP2,HNRNPK,GUCD1,DVL2,RIOK2,PPWD1,PSMB11,RAB18,CXCL3,GLIPR1,EIF3D,BANF1,KPNA1,CIMIP1,MAGEA4,NCSTN,TOMM40,CHMP5,NR4A2,GPM6A,EIF3K,ATG101,ZNF704,GSTA1,RASGRP3,MGMT,TRMT13,BSCL2,KLRF1,LCA5L,CARD19,MRPL49,STC1,AURKAIP1,TIMM29,PCK2,COX6B2,NLGN1,TES,CLEC2B,BICD2,LMNB1,CETN2,PABPC1,SERPINA3,LAP3,MED31,TMEM179B,FNDC9,SERINC3,GAB1,ARCN1,TPSG1,SLX1A,SLC25A12,EIF5B,TTC9C,THUMPD1,GARRE1,CELF6,EEF2,ZNF575,SNRPN,GNAI3,DRG1,ACBD6,TIGD7,FCHO2,MTA2,ALKBH3,PLSCR3,PELI1,CDH11,KCNIP3,NDN,TMED9,ATP6V1G2,TBC1D25,CD79B,ARHGAP21,MTERF2,NONO,NPTX1,OR8K1,NDE1,SERTAD3,MFN1,FXN,TMEM106A,EDNRA,CCNI,ATF3,PRELID1,MIR223,RAB14,HIRA,MRPS18C,CCNY,CDC42EP2,CASK,MAEL,MIR148B,MIR214,ST7,UBE2A,SH3GLB1,GTF2I,OPTN,LRTM2,POLR2F,PAK1IP1,TMEM243,DFFA,YPEL4,DYNLRB2,NXT2,FKBP10,COMMD9,PNPLA8,SMCP,MARS1,TAMM41,CDK6,PRMT2,CFAP418,LGALS3,RGMB,HSPA5,TEDC2,SLC25A46,RSL24D1,TOPBP1,MIR193B,CPXM1,MRGPRX3,BPIFB1,DCAF4,CARHSP1,GDE1,FAS,NDUFAB1,AR,HBB,RNASEH1,HNRNPD,LRAT,ALB,STN1,ZNF518B,NKX6-2,CYB561,SURF6,RND2,TNRC6C,AIP,AIG1,RHOB,TIA1,CYP4F12,GNRH2,IPO8,AHSA1,TLR7,UBE2E3,MIR640,HMOX2,ATF4,E2F6,DNAJC4,SRSF10,SLC7A9,TASL,KLC2,MIR211,RFTN2,NOL7,EEF1E1,ZNF622,TOP2B,FAM20C,JPT1,UBE2G2,ACP5,ADRB1,FEM1B,DTD1,RAPGEF5,CCL19,NXPH3,PML,RPL15,EI24,NUDT2,SREK1IP1,SPATS2L,PTK7,FUNDC1,SFRP1,RAB11B,GLCE,MRFAP1L1,MAP2K3,PRPF31,NAE1,ZDHHC4,PITPNB,CDC42EP3,OSGEPL1,VAMP3,SRXN1,HMGN4,TRAPPC1,TRAF1,CNIH1,CTNNB1,GPX1,CYB561D2,MIR657,THY1,RRN3,UBE2L3,MCMBP,IFNA2,RIC3,VAMP8,EHD4,WDR3,SCLT1,PKIG,FAM107A,RBBP4,PGAP3,TST,BHLHE40,CHIC2,SLC38A7,TENT5C,SNX33,FAXDC2,TACR1,RB1CC1,RBBP7,CPSF4,DEFB124,TSSK1B,TSR2,MIR194-1,BOLA2B,CIMAP1B,SAT1,SMAD3,GGT7,P2RY1,LACC1,TCOF1,DNAAF9,PGRMC1,GRAMD2B,TMEM144,SPINDOC,TUFM,SLC38A1,CSTPP1,CH25H,RRAS2,NSG1,UBE2W,BAK1,SNAI3,MAGEH1,OPRM1,PTTG1,MYLIP,PYCR2,RGL1,DDIT3,RAB33A,TAPBPL,SLC6A11,RLIM,INPPL1,DXO,DNAAF10,PCLAF,PDCD1,PIK3AP1,MDH1,MIR383,CACUL1,PNOC,MIR215,GTF2IRD1,ZSWIM7,OR8I2,SLC31A1,PEX3,RAMAC,AGO1,TBCCD1,CCR6,NPM3,BRI3,CCR1,POLR3H,PDIA3,ETFB,MOXD1,ARL10,GPR15,DLG1,PGAP2,GREM1,MIR320A,RPS29,VGLL4,BHLHA9,TMOD1,HNRNPH2,LCP1,PRCC,BCL10,LCORL,NCR3LG1,KCNC1,IL15RA,SGIP1,FAF2,SOD3,BTG3,GOLGA7,PTP4A2,TLR3,TANK,MIR147A,CTSD,KRTAP4-1,PRPS1,NTNG2,DEK,RPL10,TM2D2,MGARP,BEX3,GNG12,PAQR8,MRPL40,ZMAT3,ARPC3,NFYB,KLHL32,SELENOK,OR9K2,CSF2,KCNJ2,NUBP2,ENO1,SVIP,HECTD1,RASSF4,ATP5PD,SMG9,SMARCA5,CHP1,YKT6,KIAA1191,RAP1A,MANSC1,CCDC174,CRB3,CXCR4,IL2,RBM17,PYM1,RNF39,MXD1,SERTAD1,B4GAT1,API5,CD1E,XPNPEP1,FOXC2,MT1X,ANXA4,FBXL14,TPRA1,MPPED2,EDF1,MB21D2,SVOP,HAPSTR1,LRRC40,RRP7A,PREB,CRADD,AAMDC,DEXI,TMEM147,CCT8,KLHL23,TLCD4,TOP1,CEP41,CPE,CLPX,TAGLN2,PBDC1,RBM23,MIR30D,CCR3,VAV2,OTUD6A,FTSJ1,GADD45G,PCDH17,DERL1,MSMB,ZNF790,CAMK2N2,RIMS3,ATP5F1A,MSH6,GJC1,UBE2V1,MMP14,ACTR1A,CDK1,NFE2L1,GLO1,MSMP,DRP2,SNCG,CDC37L1,CLIC4,NDUFS8,MPIG6B,GLOD4,TOMM7,SSU72,TKTL1,SCAMP5,HEXB,H2AC1,GNAI2,EPO,NAT9,LYSET,IDH2,IL1R2,IGFBP4,RPLP1,PLPPR1,MDC1,TMT1A,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1S,UTP25,TIRAP,BMERB1,ACTR3B,MIR143,UCP2,YIPF5,RAP2A,GPHN,PIP5K1A,TMEM107,ZBTB33,RALA,KCNQ5,RPL27A,CIBAR1,SLC30A5,PSMA4,NUDT3,NETO1,TSSC4,BPIFA2,RAB3D,WDR12,INSYN2A,MAGOH,TRMT112,NEFL,DHX15,INA,DRD3,SMIM11,RNASET2,MGAT5B,BPIFB4,ZNRF1,ORAI2,ERAS,CMA1,ALKBH5,MRC1,SERPINH1,PRDX1,SMAP2,MIR148A,MIR298,NTAQ1,CYP4V2,THBS3,EYA3,B3GNT2,TAL2,RTP4,PDCL,MIR136,RDM1,METTL14,TAX1BP3,OSGIN2,TMEM95,VAC14,BPNT2,FN3KRP,UBXN10,KCNG3,TRIP4,H2AJ,MTARC2,CDK5RAP3,DAG1,LHFPL4,BLOC1S2,GDI2,ELK1,TBCE,EIF4E,SULT1A3,BLOC1S5,TNF,ADRA1A,IQCF5,GTF2E1,SLC37A4,LY96,MIR30A,KCTD10,EHHADH,GPR17,IGBP1,CLEC18A,NKAP,MAD2L1BP,RPS2,MRPS21,RHAG,ACCS,COX17,HP1BP3,ZCCHC12,PGM1,CLTRN,SOX9,EXOC3,SYNGR1,TRAPPC2L,IFRD2,PAFAH1B3,BVES,PRR5L,RPS5,LILRA1,DDX4,PIK3CA,MET,MIR198,MTPN,RNF126,POMP,RFC2,NDUFAF4,RPA2,PTGES3,TNFSF12,DRAM1,CTDSP1,TOR3A,GPBP1L1,PIWIL1,DRGX,TRIM29,CTDSPL2,ABHD17A,PLCB2,NDUFB7,GTF2A1,CDC20,CYP2D6,REG1A,CCDC181,ELAVL2,MMP9,MX1,SLC25A23,PCGF2,RBPJ,KATNAL1,PSD2,PSMD10,DEFB121,TIMM23,ARMCX5,PDE6D,KRTAP12-4,ABCG2,MAD2L2,PHYHIP,BORCS5,FBXO7,ARMCX3,ZCRB1,UCK2,CFAP161,RHBG,PTPN22,CLU,OLFM2,ZFP1,STK38L,UBR7,IGFBP3,YWHAH,UBE2M,RFXAP,CYBRD1,RP9,TIMMDC1,TLR6,PFDN4,STOML2,NAIF1,PHOSPHO2,DNAJB2,LYPLA2,REN,SEPHS2,TRAM1,COP1,DNAJC1,UBIAD1,CNPPD1,DIRAS1,CYP4F8,TP53INP1,MIR212,DDX39A,MIR206,POLR3GL,LSM3,MIR30B,CAPN1,PRKX,ALYREF,RPL31,DLGAP4,ALDH1A3,PSMB9,POC1B,ZC3H11A,ATP6V1C1,CD200,TMEM190,BPIFB3,ARL6,WWP1,SEPTIN6,RPAP3,COA5,SIAH2,LCP2,PRCP,AVPI1,SRSF4,RIT2,FRRS1,GADD45B,EMX2,IFNB1,OSBP,TNFAIP8L2,HINFP,SPSB1,RPS14,PAPOLA,TRA2A,FCAR,SRP14,VMAC,SKP1,SACM1L,SOCS2,TOR2A,MPST,GRIA2,LARP4B,H3C1,SAP30L,SESTD1,XAF1,SYT4,SOX2,TNFRSF1B,ACTL6A,GUK1,BRD3,MFSD5,DGCR6L,ATL1,RAD21,PDSS2,VGLL2,LAMP2,ASPA,TXNRD3,TIMP4,RP2,PGR,SPMIP10 |
| 1.981e-14 | -31.55 | RPLP0P6 (ribosomal protein lateral stalk subunit P0 pseudogene 6) | protein interactions | 220717 | 125 | 76 | 19454 | 5460 |
MOV10,RPL6,RPS2,RPL23,RPL10A,RPL24,NCK1,RPLP2,RPLP1,RPL9,EEF1B2,EFNA3,RPL12,RPL8,RPL32,DKC1,HSP90AB1,RPS10,RPS16,NOP58,RPS27L,RPL7,RPL29,TUBA1A,EEF1A1,RPS7,RPL15,EEF2,RPSA,RPS11,ILF2,RPL18,RPS23,TFCP2,CHMP4C,RPL23A,EWSR1,RPL3,RPS24,RPL31,RPS27A,RPS13,RPS4X,MEPCE,RPL17,VDAC1,TOMM40,RPS17,AR,MAT2A,RPL7A,RPS5,RPS26,RPL37A,RPS12,RPS20,RPS3,TUBA1B,RPL22,RPL19,RPL10,RPL10L,SLC25A4,CDC42,MTF1,RPS14,TOMM22,HEXIM1,RPLP0,HECTD1,PPT1,H2AC7,RAB5A,RPL27,RPS28,RPL4 |
| 1.989e-14 | -31.55 | TUFM (Tu translation elongation factor, mitochondrial) | protein interactions | 7284 | 655 | 273 | 19454 | 5460 |
TUBA1A,EEF2,TOP3B,ETFB,MTA2,NDUFA12,RPS23,NUDT19,PLS3,PDHA1,SCPEP1,RPL31,PABPC1,HNRNPDL,KRAS,KGD4,MRPL9,NDUFV2,XPO1,DDRGK1,GSTM3,RPL6,ARMC8,AK2,AGR2,CORO1C,RAB33A,PNPLA8,CHMP2A,HSP90AB1,HNRNPL,FUNDC1,NDUFAF3,MRPL12,FBXO42,PAFAH1B1,PLAA,MRPS18A,HSPA8,HDAC5,EP300,DDX39B,BMPR1A,MRPS7,UFL1,NDUFS2,PHB2,ADRB2,BTF3,MYC,HNRNPAB,RPS26,COP1,MRPS25,SMU1,MRPL13,TACO1,IRF2,LMBR1L,DLST,PPP5C,ATP5F1B,HADH,METTL15,UBL4A,ATP5PB,MRPL47,CAPN2,GFM2,SLC25A24,TFCP2,RPL3,MRPS18B,ERO1A,SNIP1,NAE1,MRPL52,MAP1B,ATP5PF,MEPCE,RPL17,SEPHS1,PDE12,MRPS33,CD81,COPS5,GAPDH,COX5A,ZDHHC15,RPS2,TRMT5,VASH1,BECN1,MRPS9,SSBP1,SDHB,SYNCRIP,MGME1,RPL32,COX4I1,LMAN1,RPS16,FZR1,MRPL10,GTF3C4,CFTR,CAPN1,CYC1,RPA2,QRSL1,TWNK,DLAT,RNF113A,GFM1,SNCG,BAP1,BANF1,GRPEL1,CLU,NME4,MRPL41,ST8SIA4,MRPL40,MAT2A,NDUFAF2,UBE2H,SPOP,MRPS16,TRIM23,MRPS28,TSSK1B,UQCRC2,RPS3,SMURF1,DUSP3,RAF1,HSDL2,B3GNT2,RPS11,EZH2,RPN1,NDUFS6,CHMP4C,HINT2,RPS24,MRPS11,HSPD1,PREPL,THNSL1,MRPS17,TNF,G3BP1,ETFA,ATP5F1D,TRIM37,ATG7,CLPX,MRPS35,STOML2,MRPS26,RPL23,MRPL18,WDR12,BRD9,ATP6V1A,RPL8,FOLR1,RPL9,PHB1,NDUFS8,EGLN3,DHX15,NUP35,RPL7,PRDX3,HEXB,SLC25A3,NDUFA5,PPARG,ATP5PO,ATP5IF1,NUBP2,HADHA,NT5C3A,PPP2R2C,PAFAH1B2,NSFL1C,MRPL16,MTG2,PMPCA,CUL3,CUL2,HSP90AA1,KLK5,RPS5,RIT1,MYO6,RPL37A,ARF1,RAN,RPL19,USP5,NDUFAF4,MRPL23,PPIF,RPL15,BCS1L,FBP1,NDUFA2,TRIM6,MRPL11,MRPL49,MRPL51,NDUFS3,RPL23A,HSD17B10,EMC2,PC,RAB1A,FAF1,MRPS18C,RPS13,FASTKD5,MRPL22,HUWE1,HSPE1,HDAC6,GRSF1,POR,TES,AIFM1,RPL12,ATP5PD,DBT,RABL2B,MRPS23,MRPL24,MRPL50,ATG16L1,TIMMDC1,SHOC2,WTAP,MRPS34,ZMYM6,HSP90B1,METTL14,MTDH,RPA3,DVL2,SIRT7,CRYZ,MRPL20,POLDIP2,PPP1R2,GTF2I,PDHB,MRPL17,FBXW7,HMOX2,NDUFB10,PYCR2,SYP,ZSWIM7,GSK3A,RPS20,PTEN,ACAT1,GAB1,CCNF,MRPL53,VIRMA,NDN,COPE |
| 2.023e-14 | -31.53 | HSCB (HscB mitochondrial iron-sulfur cluster cochaperone) | protein interactions | 150274 | 811 | 326 | 19454 | 5460 |
COX5A,ACOT8,DOLK,NUS1,AKAP8L,COX4I1,UBE2G2,NDUFB4,SDHB,SSBP1,STT3A,MRPS9,GNPAT,TRAPPC3,TMED9,ILVBL,MTCH2,MRPL47,PREB,RRM1,GLRX5,HADH,ACADSB,SH3GLB1,ATP5PF,NOSIP,TRAFD1,ABCE1,STX18,MRPS18B,RPIA,MRPS33,PDE12,MPST,RDH11,GSTK1,NDUFAF2,RPF2,PHKA1,CNNM4,TIA1,ARHGAP21,CHCHD4,MRPS16,CISD1,ALKBH5,OAT,CDIPT,ACOX1,MRPS28,GRPEL2,MRPS21,GPX1,MKKS,RALA,DUSP3,SUCLG2,MPV17,AKR7A2,MRPL10,STX17,IDH2,QRSL1,CSNK1A1L,SDCBP,CYC1,ITM2B,POLD2,DLAT,TWNK,MRPL40,FTSJ1,MRPL41,NME4,OGDHL,GRPEL1,PTDSS1,RIOX2,CNOT2,LAMP2,DDRGK1,CBR4,NDUFV2,MRPL9,CRTAP,DRG2,NDUFB8,PEX3,MPDU1,PTK7,STX5,FAHD1,AASDHPPT,ECHDC1,NOB1,RMND1,LANCL1,TOR1B,ETFB,PDHA1,PTRH2,KDELR1,DCUN1D5,NDUFA12,FBXO3,NDUFB5,SCPEP1,CDK5,KGD4,KRAS,USP30,COX7B,DCTPP1,CPSF2,COX11,BTF3,MRPS25,SPCS3,PDF,FIS1,DLST,TACO1,MRPL13,TRMT11,RCE1,STAT1,ATP5F1B,TAMM41,SHMT1,MRPL12,NDUFAF3,ISCU,QTRT2,YIPF5,MAP2K1,UBAC2,PPT1,SIGMAR1,ACAA2,TRMT112,OGFOD3,ARG2,DDX39B,MIA2,DDX5,P4HA2,RER1,SSR3,EMC1,UFL1,NDUFS2,MRPS7,RPP14,EI24,GRSF1,LRRC40,HM13,ECD,MUL1,ARL10,SRPRA,PTPN1,HDHD3,PWP2,HSD17B11,MRPL50,DERL2,RPL35A,MRPL24,MRPS23,G6PD,MSMO1,ATP5PD,NDUFA2,CMPK1,TOR3A,BCS1L,AGPAT5,MAP2K3,DDX39A,NDUFS3,DHRS7B,RAD23B,MRPL51,MRPL49,VAC14,TMED1,NSDHL,SDHAF1,HSD17B10,EMC2,SNAP23,TMX3,FN3KRP,TTC4,ABHD10,MRPL22,FASTKD5,CTNND1,PYCR2,CSK,RETSAT,HSPA14,NDUFB10,HMOX2,STK24,GGCX,AP2A1,INPP5K,MRPL53,SFXN2,ODR4,CPT2,ZNF622,VKORC1L1,UBE2L3,PCK2,LIAS,COQ8B,HACD2,MRPS34,P3H1,AGAP1,OXSR1,IDH3A,PRIM2,MAVS,GPX4,NDUFC2,SPCS2,PDHB,YKT6,MRPL20,POLDIP2,DAD1,STOML2,MRPS35,CLPX,PIK3R1,ATG9A,MMUT,RHOG,MRPL18,CDK5RAP3,DICER1,MRPS26,MPP1,ATXN10,OS9,STK3,SRSF10,NDUFS8,DLG3,HSDL2,DCAKD,LYPLA1,GFPT1,CYB5R1,FAF2,NDUFS6,BZW2,STIM1,CYB5B,POLR2C,STX12,THNSL1,SYPL1,NDUFA4,NEK9,PREPL,HSPD1,MRPS11,HSD17B8,PCNA,HINT2,ETFA,EMC8,RFC2,SACM1L,HS2ST1,RFC3,GTF3C3,MRPS17,TXNRD2,PYCR1,CDC123,VEZT,ALDH1L1,NDUFB6,ACO2,GGH,RFC5,SAMHD1,MRPL16,NOA1,BLVRA,VMP1,RIT1,BAX,PELO,CYB5R3,GNG12,CPSF1,LRRC1,RMDN3,UMPS,MRPL23,TNPO3,NDUFAF4,PARL,USP5,ABHD12,MAT2B,TOR1AIP2,NOTCH2,AGTRAP,NDE1,GK2,IDH3B,ARMCX3,NDUFA5,DUSP9,HADHA,RBP5,NUBP2,HSCB |
| 2.046e-14 | -31.52 | PCBP1 (poly(rC) binding protein 1) | protein interactions | 5093 | 629 | 264 | 19454 | 5460 |
MACROH2A1,EIF2S2,PITPNB,SRPK2,SMURF1,CFL1,TIA1,RPL7A,TNFAIP3,SLC25A1,UBE2H,IGF2BP1,BICD2,RC3H2,EIF3G,GLOD4,RNF113A,LSM12,PML,RPL27,BAP1,SNCG,HSPA5,UGP2,CFTR,CD2AP,UBE2M,HEXIM1,WWP1,WRAP53,RPA2,DSTN,SYNCRIP,CDC5L,TMPO,RBM42,MBD5,MIF,RPS16,CAND1,ELOC,API5,CD81,COPS5,RBM17,MAP4,RPS2,RPL24,SNRNP70,DHX9,IDH1,RPL3,CAPZA1,MEPCE,HNRNPK,KPNA2,MTCH2,TP53,UBL4A,RNF8,PIK3CA,RPL10,DES,MATR3,ATP5F1B,TAGLN2,BTF3,HNRNPC,MYC,SERPINH1,RPS26,ADK,DDX5,EP300,YAF2,PCGF2,HSPA8,XRCC5,SNRPA,BMPR1A,DDX39B,ADRB2,STAU1,FXR2,HNRNPA0,UFL1,ATP6V1C1,RPL27A,PIH1D1,CNDP2,AKR1A1,NUFIP2,PPT1,MRPS18A,ADSS2,FAHD1,HEBP1,EED,FUBP3,HSP90AB1,TCP1,HNRNPL,DDRGK1,CTNNB1,ZCCHC10,WWP2,RPL6,PEX3,DDX1,FBXO11,EWSR1,RUVBL2,RBM3,PABPC1,CCT8,RPL31,RPL28,RPS4X,FOXN2,RUVBL1,KRAS,HNRNPF,EEF2,ISG15,H1-3,PPIL3,UBL5,TRMT1L,RPL18,TAF10,RPS23,MTA2,TUBB4B,RPS20,PRKRA,CYRIB,CTTN,EIF2AK2,STUB1,CCNF,VIRMA,RPL13A,TXN,COPE,ZNF622,NDN,AR,NONO,PPP1CC,TUFM,RACGAP1,FBXO7,RPL26,CTSD,PPIG,CDC73,SMAD2,MAVS,PRPF4,DVL2,RPA3,SOD1,PIAS1,RPL4,FBXW7,CDK7,FTH1,CCND1,RBFOX2,RPS14,CARHSP1,RPLP0,HNRNPH3,MET,METTL14,CDK1,LMNA,MRPS34,RPL12,ZBTB2,CDK9,RPL35A,KLF1,HDAC6,EMC4,ERCC3,EPOP,NOVA1,RAB1A,EIF3E,ARF4,THRAP3,HUWE1,RPL15,MAP2K3,EEF1A1,SRP72,ILF2,HSPA13,RPS9,AP2M1,SNRPD2,RAN,PELO,ERH,RPL19,DYNLL1,TUBB,EIF4A2,PRDX2,RFC5,CAV3,CUL2,NOP16,CUL3,HNF1B,ACO2,RIT1,BAX,BOLA1,HSP90AA1,MYO6,BRCA1,PSMA3,CRY1,NMRAL1,UPF3B,SKP1,ANXA7,RPLP2,PCBP4,IGBP1,PHB1,RPL9,RPL8,DHX15,EGLN3,HYPK,CCAR2,RPL7,HNRNPA1,PIK3R1,CRIP1,HMGA1,COTL1,CAMSAP2,RPL23,BCL2L1,HNRNPD,ZC3H7A,PPAN,ARGLU1,HNRNPA2B1,TRIP4,SLC25A5,RFC3,EIF2D,B3GNT2,RAF1,RBM12,ANP32A,NGB,VPS33A,EZH2 |
| 2.180e-14 | -31.46 | regulation of response to stimulus | biological process | GO:0048583 | 4104 | 1406 | 18204 | 5365 |
SLC7A11,MIR24-1,SMAD3,DUSP22,CD63,CCN3,CRHBP,TAF9,RHBDD3,KLRC2,TMEM108,KMT5B,EIF4A3,TRIM62,SELENOK,MIR205,WDR83,RALB,ATF3,FCGR2B,STAP1,TAFA1,PSPC1,CHI3L1,FAM168A,SOSTDC1,ARG2,NFKB1,KCNJ8,EFHD1,SUPT3H,KCTD16,IGSF11,MIR181D,THBD,TRAF6,NLGN2,MIR222,TICAM2,CCL19,TRIB1,BIRC5,GPR37,TAB2,IFNG,PDCL,PRKRA,MEF2A,LGR4,EXT1,FAIM,MTMR2,MIR34C,CDK20,ADRA1A,SRC,PSMB4,ANGPT1,TFPI,HEXIM1,CD1A,TRIM21,ATF4,HNRNPK,TICAM1,MIR181C,NDC80,BMPR2,ADGRG1,MIR29A,EXOSC3,MOG,PQBP1,IRF1,AFAP1L2,IFI16,NTRK2,TFIP11,LMO3,CTNNBIP1,SHOC2,BPIFB1,NBN,ACTR2,EP300,VDAC2,BOK,CTSK,CCL24,TMEM106A,GPX1,ZMYND11,LMNA,UBE2V2,FAM53B,MIOS,STARD13,MIR136,MIR99A,PRMT5,GABARAP,MIR92B,SDHAF2,DRD3,SELENOS,GRB10,TANK,BCL2L1,LIMS2,P2RY10,MIR573,BST2,TIRAP,TSPAN15,RAMP3,GSK3A,G0S2,BAD,SSX2IP,AATF,ADRB3,HTRA1,MIR206,ARRDC3,DIRAS2,TRIM24,CRKL,FOXP1,PEA15,STOML2,DUOXA2,MIR185,POLR3B,UBE3A,IL12B,RNF14,USP2,RSAD2,MIR107,BGLAP,UBB,DLGAP4,HSPD1,VDAC1,MIR885,TMEM196,MIR449A,FLOT1,GPR37L1,LYAR,SIN3A,RRAGB,VAV2,MIR210,POLR3F,ZNF592,RMI2,RTN4,RGS10,RGCC,MIR375,LILRA2,MSX2,MIR30B,CD9,MIR519D,VWF,ADIPOQ,FGF17,LBH,ROCK2,TRAF2,TRIM6,RPS3,MIR495,YTHDF1,CXXC5,INO80C,EPHA2,STX1A,AGER,MIR23A,MIR361,BATF,MAPK10,PLEKHF1,PSMD10,CXCL10,TNFRSF14,RPF2,SPHK2,ZNF622,NKIRAS2,H2AX,RAG1,FBXW11,MIR424,OGG1,DDR1,AIPL1,MIRLET7C,GAS2,MIR657,UFM1,RHOH,TAF7,DIPK2A,IDO1,CD1E,SPPL3,ZNF451,VPS72,IL21,CLEC7A,MIR34A,IL13,FGFR1,NETO1,MICB,PTPN11,TFPT,NONO,GHITM,DHRS3,FAM13B,TRIM27,TPBG,GAPDH,TGFB1I1,CNOT7,FZD6,PYCR1,IL7,ITK,OSBPL8,RAP2A,PDE9A,STK24,GPNMB,RELL2,JUP,RACGAP1,LIPA,CSNK1A1,PTGER4,RPL23,SFRP4,SVIP,NOTCH2,ACTA2,SLC6A3,TGFB2,CHP1,FCN2,CLPB,CRYBA1,PAK6,MIR144,GKAP1,PCNA,SPRED2,USP13,SOX2,PTPN22,PDE8A,NFKBIB,C1QC,CDH13,ENHO,ADTRP,MTDH,GREM1,ATP2B4,MAD2L1,USP14,MIR708,TMEM170B,RIT2,MACROH2A1,TMOD2,PAGR1,PRKCB,CHGA,SHC1,TRAF3IP3,RAP1B,MIR20A,CCL21,PRCP,TADA3,TNR,CTNNA1,IFI35,G3BP1,PEG10,WWP2,DOK6,IER3,FRMD8,IFNAR1,GPR17,PTGES,ZFAND6,APOBEC3G,SASH3,INPP5K,HTR2A,PELI3,APLN,SMAD5,SOCS4,USP15,HSP90AA1,AKIP1,SLC20A1,TRIM11,GPBAR1,USP8,RC3H2,VGLL4,FKBP1B,HSP90AB1,CD28,TAX1BP1,MEF2C,LYPLAL1,MSTN,CAV3,ARHGAP19,IFIH1,MIR208A,ZMPSTE24,CNKSR3,GFI1,TAF2,SNX3,ABHD12,TRIM26,HBEGF,PPP1R2,ARL6IP5,LILRB4,VSIR,MIR101-1,CERS2,TRIM32,KBTBD6,SYK,FGF16,NLRP1,CCR4,TXNDC12,FBXW7,S100A8,NOG,PRR5L,ZDHHC17,TRIM5,NPPC,NPSR1,DUSP6,CHCHD2,CCL2,JMJD8,PDE2A,PSD2,DMPK,G6PD,RARRES2,MIR373,SLC12A2,CD1B,DPP4,TMEM97,VAMP3,DIRAS1,TBK1,CYRIB,XRCC5,CD47,PIK3CA,IL17F,TAF10,F7,ICAM1,RGS7BP,TCIM,NLGN1,ROCK1,P2RY12,LYPD6,ZFAND2B,MIR15A,LAMTOR3,PRDX1,CSH1,RB1CC1,BACE1,PDE4B,MIR140,THY1,RNF41,TNFAIP8L1,MTPN,PRELID1,FGF23,PPM1B,CARD19,RALGAPA2,IL23A,VEGFA,TIMP1,SAMHD1,PIK3R2,PRKACB,CCL1,YWHAZ,OSM,DEK,AREL1,SERPINC1,FZD4,RXFP2,NFKBIA,SAP30,CIBAR1,LPAR6,SPRED1,FBXO9,TAX1BP3,GRPR,SIRT7,RGS5,VDR,BAK1,KICS2,ARFGAP1,NPY,WNT7A,SIAH2,TGFB3,DUSP26,NCR3,TMED4,RPL26,ITGA2,GPC1,SLC25A31,PPP3R2,PIP5K1A,MIR125A,FGF1,ACP5,RPGRIP1L,NRP1,PCSK9,MIR187,PRKCE,GLCE,RGMA,MIR10B,PARL,XBP1,CD59,PATE4,PID1,CAAP1,TRIM63,MIR130A,PAK2,MIRLET7B,IL2,SOD1,AR,FCAR,LAT2,CNR1,MACIR,TMEM100,UBE2K,MMP14,MOSMO,NDST1,PTP4A3,ASPM,GADD45G,PADI2,ACTL6A,PPP2CB,AKT3,CD274,FOXP3,MIR1224,SPRY1,HAX1,GRAP2,SMARCE1,RIGI,PEX5L,SAR1B,SIPA1L1,WNT10B,OPTN,BABAM1,PNPLA8,SLC35C1,HHIP,CASP12,IFNK,SMARCD3,HDAC3,SH2D1A,OCIAD2,NACC2,AQP11,SEMA4C,DNAJB6,SFN,LCP2,MIR96,TMEM204,TNIK,CAMK2N1,CX3CL1,MIR1298,NDUFAF2,MUL1,FCGR2A,TESPA1,PHB1,RPA2,ING1,FGF7,STUB1,CXCL12,CLDN4,MIR98,HECW1,CHRDL1,DUSP10,LSM14A,MIR105-1,MDFI,CASP4,EID2,RNF152,ILK,TNFAIP1,GGT7,ZNF365,GPR89A,GNG7,NLRP2,NPY5R,YWHAB,MIR214,CASTOR2,NLRP3,ARF6,CLDN3,FUT8,IRF4,CSNK2B,SDCBP,MDM2,FADS2,TP53,MIR1-1,DDX5,TMEM33,ACKR3,PTPN1,LILRA3,HSPA8,ST3GAL4,CRBN,JADE1,IFI6,DLG4,CER1,LGALS3,CYP27B1,TRIM15,MIR195,FAF1,MIR198,DROSHA,MLC1,TRIM52,HOMER3,CXCL13,UFL1,TNNI1,SLC15A2,CD247,DUSP3,MAP2K3,KLHL15,SESN3,SHISA2,JAGN1,OTUD7B,MIR9-1,GAS8,VAMP8,TRAFD1,DKK1,GLRX2,SEMA5A,STAT6,RNF8,SETD9,CCR7,HAND2,C9orf72,ADRB2,CD200R1,FKBP1A,GRAP,CYTH2,DHX15,PELO,ING5,SAP30L,CCR1,NUCKS1,CCDC92,GHRL,PROK1,CSNK2A1,SOX9,RHEB,CBL,NDFIP1,SNAI2,LTBR,SPEF1,RGS19,CCL5,TRIM68,TLR3,AKAP12,DYRK2,UBAC2,FLCN,MIR302B,NUPR1,DUSP19,SOCS2,MIF,HNF1B,REN,MIR132,BCL10,IL12A,RWDD3,ELMOD2,MAP3K12,HEY2,IRF3,RNF34,OPRM1,STK3,FBXO8,CPTP,CSNK1G3,SWAP70,CMA1,TADA1,GPR35,LANCL2,ING2,DKK3,RUVBL2,CYTH1,IL4,GADD45B,FXN,MIR146A,NT5C2,ALKAL1,LMBR1L,SARM1,RAP1A,MIR920,PIK3AP1,GIT2,TFRC,DDIT4L,CLU,CISH,OTULIN,MINAR1,NKX3-1,NFKBIL1,RPS7,PSMA1,STK38,ADIPOR1,BMPR1B,TASL,HCLS1,DISC1,PML,SPATA2,MIR141,CHN2,CRADD,TERT,ALOX5AP,CD2AP,CD38,LAMTOR1,DNAJC7,GSKIP,GADD45A,FKTN,NDP,TLR10,GRM2,TLR5,JPT2,NINJ1,CTLA4,MIR34B,ARHGAP5,MIR873,RNF146,SERINC3,DOK5,TRIM45,MMP28,TNFSF12,DAG1,SH3BP4,PHB2,FGL2,SLC25A23,CD200,EPS8,WIF1,LEP,SQSTM1,PRMT6,AKR1C2,NFE2L2,FBXO7,BMPR1A,SMARCB1,IVNS1ABP,LILRA1,SEMA7A,LPXN,UBASH3B,GTF2IRD1,MIR100,TRIM3,BRMS1,NTRK3,TLR8,MIR296,CCDC3,EIF2B5,SNX5,PDCD10,CAMK2G,KARS1,CTNNB1,HYAL2,SHLD1,KLK5,CYFIP2,RALA,UBE2V1,MIR1271,NOP53,ARHGAP15,INO80E,SMAD4,MORF4L1,PTEN,JAK2,MCPH1,IRAK1BP1,STX7,TTI2,STAT1,DVL2,LACC1,CRY1,DEFB114,FGD2,UGCG,SMCHD1,TNFSF13,CD14,EIF2AK2,IL22,GNAI2,MIR221,UBE2N,CARTPT,MIR497,RRN3,NCOA5,YWHAG,BRAP,FGR,ERP29,SPG21,STAMBP,CSK,ABHD6,JUNB,OTX2,MIR186,TRIM34,PRL,CD79B,LDLR,ENO1,DMAP1,PPP4C,GRM1,MIR10A,ADRB1,NEUROD2,PPARA,PELI1,VEGFC,TRAF7,GPC4,PAK5,TTC23,SERPINB9,BAP1,PMAIP1,MIR129-1,TPT1,CD36,TCF21,NDUFS3,EMP2,SMURF1,ELAPOR2,PEBP1,UBE2B,HACD3,GLIPR2,PROS1,CPNE1,FGFBP1,MIR21,CACNG3,MAP3K11,DDRGK1,CRLF3,RBBP7,CACNB3,RAF1,SLC39A10,IL10,TRAF1,MSX1,CX3CR1,MIR145,DBH,VAMP7,LY96,CD1D,HMGB1,MAPRE2,BCL7B,FEM1A,MBL2,ABHD17A,KLK6,PTK7,CDC42SE2,RGS2,MPIG6B,TMEM198,CXCR4,HRAS,PYCARD,CD226,RELL1,INPPL1,VAMP2,HAPSTR1,CGAS,CTTN,ADNP,STRADB,PRKCA,EIF4E2,CD1C,ACVR1,PIP4K2C,CCR2,F2,PLSCR1,BCL7C,CAPN1,TMEM126A,MIR133B,CCNY,LPAR1,CXCL8,RRAGA,RGS1,LCMT1,FKBP8,CTSC,ITGA6,AZI2,ARHGAP21,UBE2D3,P2RY1,PLPP4,MIR340,PRDX2,RAC2,FGF22,NKIRAS1,ADORA1,TOMM70,MIR590,DNAJC2,EYA3,DDIT3,NR4A2,EPO,FSTL1,EGR1,IKBKB,IL34,MKKS,LEMD3,YTHDF2,RPS20,MIRLET7G,CHRNA7,EZH2,UFD1,F11R,PRKCQ,SLA2,MIR106A,SESN2,ZNHIT1,TMEM237,PPARG,CCDC22,PAQR3,SRARP,MBD5,KRAS,PAK1IP1,IL1A,FGF10,NCK1,GCLC,DYRK1A,DDIT4,KLK3,MIR152,CREBBP,PROX1,CYTH4,MIR200C,NLRP6,H2BC11,IRF7,MIR1260B,ACTN4,CAV2,LTA,FOSL2,COPS5,RNF126,OAS1,ARHGAP25,TRIM22,FAM3A,CTNNA2,AIP,PICALM,LITAF,SLC35F6,ADAMTS20,CASK,GPSM3,SOS2,LRRC14,PHF13,DLX1,MYC,MIR126,DAPK1,HSPB1,MIR490,MIR142,CYP26A1,DDT,SNIP1,ATP6AP2,SOCS3,IFNB1,CAV1,TAB1,TNKS,MEAF6,PIM2,CDKN2D,SUPT7L,MIR342,SMAD2,BRCA1,MIR31,BUD31,APOBEC3F,FAM83B,CLDN1,CD4,RNF113A,PTN,PSEN1,TNKS2,MTM1,SPTBN1,KCTD10,SCYL2,PARP2,PDCD1,EGFL7,BIRC2,DUSP1,YES1,LACRT,BFAR,ACVR1B,TMBIM6,CD40,ARFGEF1,RGL2,MIR208B,HDAC6,SGF29,CREB3,STK11,CCAR2,MAP2K6,IL2RA,NHERF1,SYP,MAPKAPK5,NUP62,WBP2,MIR16-1,CACNB4,PIH1D1,DRD1,OPRL1,DUSP9,CLEC12B,CTNND1,MIR183,TLR2,CYP1B1,CSNK1A1L,RNF26,PPIF,NLE1,PAFAH1B1,TIAM1,PDCD4,NEO1,GTF2H2,PBLD,IL18,WRAP53,SCHIP1,NECTIN2,PIK3CG,INSIG2,FASLG,RPS12,TLR1,IL15,FABP5,BCL9,SLC38A2,RGS6,RNF115,NF2,LAMTOR2,MIR874,PRRT1,ZNRF1,PIK3R1,SETD4,NR0B1,CUL3,MIR30E,MIR218-1,OPRK1,NIBAN2,CCNB1,IGF1,CNOT2,UBE2W,ENY2,SGMS1,UCP2,ABCB1,MIR675,CALR,RBBP4,GH1,TNFAIP3,TXN,GID8,GSTP1,MT3,INPP5E,MIR182,PPP3CA,HERC4,AKT1,IL1B,RADX,AGR2,TLR6,TFG,PPP5C,TSG101,NR1H2,PLA2G5,CDK5RAP3,SYVN1,TMEM88,TSPAN5,MET,DLK2,FAS,KIT,TGFBR2,KLRD1,UBE2D1,DNAJC27,MIR223,ELF1,FCER1G,DDX1,KPNA1,USP38,ENPP4,BAX,TRAF3IP2,MOB3B,IL6,EFCAB7,AGPAT1,CD86,ACAA2,PYDC2,MMP9,GNAQ,PSMA6,FAM89B,ERRFI1,MATR3,OXSR1,PRNP,IQSEC1,CDC42SE1,GPR137,TMBIM1,DAPK3,OR2AT4,MAD2L2,GPR65,MIR204,CLEC6A,DSTYK,EDNRA,NMI,LPAR2,UCN,VPS18,CD80,CNRIP1,TLR9,PLCB1,TNFRSF1B,LEPROTL1,MGST2,MCL1,SELENON,SLC39A9,IFNA2,LPCAT3,CDC73,FABP4,PPP1R10,TWSG1,FGF3,ACTB,TNF,BRMS1L,XCL1,RBPJ,SEC13,AVPR1B,SLC25A4,RUVBL1,PDIA3,EDA2R,TOP2B,DDAH1,BCL6,RHOU,CTDSPL2,PFDN5,HFE,ARHGAP12,TBC1D24,EMILIN1,FBP1,LURAP1,PLG,MZB1,FOLR1,CDK9,TMSB4X,TBC1D10C,PTPMT1,RB1,CITED1,SLC25A5,GREM2,GJA1,MIR17,CEBPG,AIF1,TIFA,FOXC2,CTSD,MAPKAPK3,LYNX1,ACTL6B,TNFSF10,KCTD12,STK4,ST6GAL1,TNFAIP6,AVPI1,SYNJ2BP,MAP3K3,SOST,NEK7,SOD2,CHORDC1,ITGAV,ARHGAP1,PCGF2,MGMT,MIR26B,LAMB2,GHR,KLF4,HOMER1,TMEM14A,ZBED3,PIP4P1,SEC14L1,RPS15,TLR4,APLNR,MPP1,S100B,HINT1,C1QTNF1,HMCES,RBCK1,TRIM44,SIAH1,B2M,ATAT1,EIF2B2,HELLS,KLHL22,CD3G,NREP,TNFAIP8L2,PPP2R1A,IRAK4,TNFAIP8L3,PI16,SUFU,FCMR,MIR503,MIR212,MLF1,SGTA,F10,MIR346,FRRS1L,PIANP,LTB,RAB29,TLE1,EIF2B3,FBLN5,TRIM8,CA8,COL3A1,DHX9,RABL3,FEM1B,FAM20C,MIR25,SPP1,CCR6,ISG15,RNF167,HCFC2,IL5,SLC38A9,MIR29C,TLR7,KDM1A,MAP2K1,PRMT2,HGS,MIR488,FCGR1A,WDR11,IGFBP4,IL1R2,HCST,RGN,STAT2,ANKRD6,BECN1,FIS1,DICER1,CBLN1,BANF1,DNAJB9,SLC25A14,IGBP1,SF3B5,DLG1,CHST11,EPHA4,DEFB124,FBXO32,CSNK1E,FERMT2,IFT172,SFRP1,IGF1R,CDC42,PPIA,FRZB,CCL3,TEDC2,SCG2,LILRB1,TPD52L1,CSF2,BTN2A2,IL6ST,DOK4,EEF1E1,NCR3LG1,TYROBP,DEPDC1B,MAVS,TMEM101,FURIN,MAD2L1BP,MYORG,ANAPC15,STAMBPL1,CDKN2AIP,BEND6,HTRA2,OPHN1,TMEM127,LDLRAD4,HSPA5,IL20RB,SOCS5,MYD88,NPTN,TAF5L,CD46,MIR149,IGFBP3,NLRP9,ATP2C1,TULP3,CD81 |
| 2.320e-14 | -31.39 | BCAP31 (B cell receptor associated protein 31) | protein interactions | 10134 | 512 | 223 | 19454 | 5460 |
VDAC2,LMBR1L,GGT7,PSMD4,CAVIN2,ATP6AP2,TMEM38B,PSMD1,FTSJ3,POLR1B,ZMPSTE24,FIS1,RAB5A,AKAP1,HSPA8,RER1,PHB2,EMC1,UFL1,RNF5,VAMP1,YIPF5,SEC62,FDFT1,RAB35,STX5,OSBP,RPS10,HSP90AB1,RAB5C,LAMP2,DDRGK1,AGR2,ARMC8,RINT1,NDUFB5,RUVBL2,VDAC1,ARHGAP15,KRAS,COX7B,STBD1,DNAJC25,ISG15,RAB4A,SERPINA5,ATL1,SF3B6,EPCAM,SEC61A1,DYRK1A,RAB2A,GORASP2,BFAR,DNAJC10,CISD1,UBE2H,CALU,TEX264,DERL1,RAB9A,HSPA5,CFTR,TRAM1,PLP2,CDC42,SSR1,USE1,STX17,RPA2,LEMD3,COX4I1,CAMLG,COQ8A,RAC2,ARL6IP5,DNAJC1,LMAN1,STX6,TMPO,DHRS7,COX5A,ADIPOR2,SMIM12,AQP2,AGPAT1,AKAP8L,NUS1,BCAP29,STX18,RAB3B,FKBP8,SLC6A8,TP53,MTCH2,UBL4A,PREB,UBIAD1,TMEM31,SLC25A24,SEC61B,RMDN3,ACTB,SCN3B,RAB11A,VEZT,TOMM40,LMNB1,SETD7,VMP1,HSP90AA1,DNAJC3,PMAIP1,TXNL1,NSFL1C,PXMP2,STX7,PGRMC1,TOR1AIP2,RAB6A,OTULINL,RND2,VAPB,KLF3,ATP5PO,PHB1,CYB5A,GJA1,SNX1,DNAJB9,TMEM237,RAB11B,SLMAP,PDIA3,CDK5RAP3,RHOG,BCL2L1,C2CD2L,CDKN1B,TMT1A,SCD5,SLC39A7,TRIM37,RBBP7,EMC8,RETREG1,SACM1L,MACO1,FAF2,GDI2,RAB6B,VAMP2,STIM1,RPN1,PLD3,CYB5B,SCAMP2,ENO1,CCNF,VAMP3,MSN,COPE,RAB14,SEC63,UBB,VKORC1L1,CIAO1,NDUFB10,CSK,HMOX2,ATP5F1A,RPA3,MTDH,SPCS2,RTN4,SYVN1,YKT6,CERS2,SLC7A1,TMEM209,TIMMDC1,ARHGAP1,SEC22B,SPR,RABL3,ST7,HACD2,HSP90B1,STOM,METTL14,TMX4,SLC12A2,COX6C,PTPN1,SRPRA,HACD3,HSD17B11,CAV1,ATP5PD,SLC25A46,MOV10,EI24,TMEM199,CALR,HM13,ESYT1,POR,OSBPL8,TCOF1,RAB1A,NSDHL,TMX3,LIPA,ERG28,DNAJC30,RIGI,OLA1,ARF4,PSEN1,CCDC47,LBR,MAP2K3,HSPA13 |
| 2.321e-14 | -31.39 | LIN28A (lin-28 homolog A) | protein interactions | 79727 | 414 | 188 | 19454 | 5460 |
HP1BP3,MIR141,RPLP2,RPL8,RPL9,MIR7-2,SRSF10,PRPF19,MRPS35,MRPS26,MIR1-1,RSBN1L,DICER1,UBE3A,RPS24,PPAN,RPS27A,MAK16,RPL29,EZH2,RPL37A,ZNF22,MIRLET7D,SNRPB2,RPL35,RPF1,RPL7L1,MRPL16,ZNF668,MIR98,RPS5,MIR363,ZCRB1,NOA1,CCDC86,ZDHHC17,MIR106A,NOP53,MRPL57,YTHDF1,APOBEC3C,LARP4B,ADNP,PRR3,MIR25,MIR106B,SRP14,KRR1,NCBP2,NOP9,MRPL24,RPL35A,MRPL50,APOBEC3F,MOV10,SPATS2L,MIR34A,MPHOSPH10,UNC50,RPL23A,ZC3H11A,TCOF1,NKRF,MRPS18C,RPS13,MRPL22,SNRPG,PAK1IP1,NOC4L,MIR15A,MIR200C,RPL15,MRPL11,SRP72,MIR17,MIR20A,PRKRA,RPS20,MIR16-1,TUBA1B,RPL26,CASC3,MIR145,MIRLET7I,MIR34C,MIR205,NHP2,AATF,BRIX1,MRPL20,MRPL17,RPL4,MIR7-3,MIR1-2,RPS14,RPLP0,RPL26L1,ZNF574,MRPS34,MIR214,SRSF1,NOB1,RPS10,MIR9-1,MIR29C,MRPL9,NGDN,DDX50,RPL6,MIR143,MIR221,MIR140,MIR31,MIR206,RPL31,PABPC1,MIR9-2,H1-6,MIR155,MIR222,RPL18,TPPP,GLE1,MIRLET7B,MRPL13,IREB2,SNRPB,APOBEC3B,HNRNPAB,HNRNPC,RPS26,NSA2,MRPS25,FTSJ3,SF3B1,NGRN,SNRPA,MRPS7,STAU1,MRPS18A,MRPS9,MIR429,DKC1,CDC5L,SURF6,MIRLET7G,CMSS1,RBM17,CDK12,RPS2,RPL10A,SNRNP70,RPL3,MRPS18B,MIR200A,MEPCE,SRSF12,MIRLET7C,MIR16-2,RPL17,H2AX,STRBP,IMP3,RPSA,MRPL47,RBM34,PHAX,RPS3,RSL24D1,RPS17,RPF2,IGF2BP1,CDKN2AIP,MRPS16,MIR10B,RPL27,THUMPD1,MIR29A,MIR107,RPS15,STK38,MRPL40,H2AC13,MRPL10,MIR34B,MIR21,MIR7-1,ZNF770 |
| 2.337e-14 | -31.39 | organelle inner membrane | cellular component | GO:0019866 | 546 | 241 | 19108 | 5553 |
UQCRH,SLC25A3,NDUFB7,AIFM1,COX7B2,ATP5PD,UQCC6,SIGMAR1,MRPL11,MRPS21,SLC25A51,COA1,TIMM29,MRPL22,MRPS18B,BOK,TYMS,COX20,TMEM160,ATP5MC1,SLC25A23,UQCRQ,SLC25A24,MATR3,NME4,MRPS26,IFI6,EFHD1,MRPS11,ATP5PB,SAMM50,PGS1,NDUFAF6,MRPL13,SLC25A26,PLSCR3,NDUFAF2,NOA1,HIGD2A,PTPN1,NDUFAF4,FAM169A,COX7A1,BCS1L,NDUFB6,MRPS25,CHDH,NDUFA5,COX7B,SLC25A31,MRPS28,MRPL34,CNP,SLC25A11,NDUFC2,MTHFD2L,MRPL23,TAFAZZIN,MRPS33,KGD4,ARL6IP6,MTG1,ATP5PF,MRPS7,SLC25A45,MRPS17,NDUFA2,MRPL47,MPV17L2,ROMO1,MRPL52,SLC25A21,COX5A,TIMM17A,MRPS16,TIMM8A,SMAD1,PLPP6,CYP1A1,IMMP2L,SFXN2,PDE2A,PARL,MRPL18,MRPL40,PPIF,TRMT10B,DNAJC19,CLPX,COX4I2,SLC25A14,ATP5F1B,NDUFS6,PHB1,SDHC,DELE1,TIMM21,GPD2,NDUFAB1,LBR,SLC25A32,COQ10B,SDHB,SMDT1,TMEM126B,CHCHD1,ATP5PO,UQCRC2,SLC25A1,MRPL53,BCL2L1,NDUFB5,ATP5F1E,TMEM177,SLC25A4,TIMM10,CYP11B1,SLC25A39,MRPL36,MTX2,NDUFV2,CYC1,NDUFB4,PSEN1,UQCR11,MGARP,PDSS2,PTPMT1,DUSP18,COX16,TMEM126A,UQCC2,MRPL41,TOMM40,GRPEL2,SPHK2,PSEN2,PLA2G4B,AGK,CBX3,UNC50,CPT2,SLC25A28,CHCHD3,GHITM,MRPL57,STOML2,MPV17,MRPS9,COX6B2,MRPL51,MRPL24,MRPL16,TMEM11,PHB2,NDUFS2,NDUFA4,DUSP21,KCNH1,SLC25A5,ATP5MC3,TIMM23,SLC25A12,ATP5MG,SRC,COX6A2,COX4I1,MTG2,MRPL9,COX8A,LEMD3,ZMPSTE24,TWNK,MRPS23,PMPCA,CRAT,NDUFB10,CYP11B2,MRPL33,MAIP1,HSPD1,TAMM41,UCP2,COX11,TERB2,IFI27,MRPL20,UQCRC1,ATP5F1A,SMAD3,HADHA,TRA2B,SLC25A10,ADCK1,MPC1,MRPS18A,ATP5MK,NDUFA12,RSAD2,LDHB,MRPL50,MRPS18C,COX6C,LMNB1,NDUFAF3,TIMM8B,CLU,NRM,MRPL10,TIMMDC1,NDUFS8,MRPS35,CIBAR1,COX6B1,TMX4,NDUFS3,DNAJC30,TMEM70,NDUFB8,SLC25A27,RPS3,SLC25A42,CHCHD6,SLC25A20,MRPS34,AURKAIP1,COX10,SLC41A3,ATP5F1D,APOO,TIMM13,CYP27A1,MRPL49,SFXN1,NDUFA1,FGR,MRPL17,LGALS3,MRPL12,UQCC3,GRPEL1 |
| 2.342e-14 | -31.39 | RPL4 (ribosomal protein L4) | protein interactions | 6124 | 682 | 282 | 19454 | 5460 |
H2AX,UBL4A,KBTBD4,RPSA,TP53,HBP1,TFCP2,DNAJC2,RBM34,RPL3,ABCE1,DHX9,PALM2AKAP2,SNIP1,MRPL52,MEPCE,RPL17,NEDD8,MRPS33,CD81,COPS5,CSNK2A1,API5,ENY2,CDK12,NOL12,RPS2,RPL10A,SNRNP70,RPL24,ARL4D,MRPS9,RPL32,DKC1,TMPO,RBM42,SURF6,DNAJC1,RPS16,CAND1,RPS27L,CFTR,DYRK2,UBE2M,ZNF770,RPA2,SSR1,ZNF326,TWNK,RNF113A,RPL27,BAP1,PML,HSPA5,RPS15,WDR3,RPS17,RPF2,RPL7A,UBE2H,RRP7A,SPOP,EIF3G,RC3H2,TRIM23,FGFBP1,SEC61A1,SRP54,SF3B6,PSPC1,RPS3,SRPK2,BCCIP,RSL24D1,RPL10L,DNAJC25,SOX2,EEF2,TNPO2,RPS7,TRMT1L,MAGEB10,RPS23,RPL18,RPL31,PABPC1,RPS4X,RPL28,TFG,KRAS,XPO1,CTNNB1,DDRGK1,NGDN,IFI16,DDX50,WWP2,RPL6,RIOX2,DRG1,MAGOH,IKBKB,AGR2,SRSF1,UQCRH,HSP90AB1,EIF2S1,RPS10,SUMO2,LYAR,RPL27A,MTF1,PAFAH1B1,FBXO42,NUFIP2,PIH1D1,CSNK1A1,HDAC5,RPS28,MRPS7,UFL1,STAU1,BTF3,MYC,SFN,ICAM1,RPS26,DNAJB6,GTPBP2,H1-1,NSA2,MRPS25,FTSJ3,PSMD14,H1-10,MRPL13,ZNF189,RPL10,APEX1,ATP5F1B,MATR3,TAX1BP1,ZCCHC7,EEF1A1,MAP2K3,TAF1D,FCF1,RPL15,FBP1,ILF2,SRP72,TNFAIP8L1,LLPH,RPL23A,FAF1,NKRF,RPS13,PTGES3,PAK1IP1,HUWE1,VRK1,HDAC6,GRSF1,SPATS2L,BRD3,MPHOSPH10,PWP2,RPL12,SMAD3,SRPRA,RCHY1,KRR1,MDM2,CDK9,RPL35A,DCUN1D1,CDK7,RBFOX2,RPS14,UBA52,RPL26L1,RPLP0,ZNF574,MACROH2A2,MRPS34,GRM2,METTL14,SYVN1,KIN,MTDH,RPA3,SIRT7,CRYZ,UTP23,AATF,BRIX1,NF2,DGCR8,NPM3,HMGB1,FBXW7,RPL26,DNAJC8,PPP1CC,USP14,DNAJC19,GSK3A,PRKRA,RPS20,RPS12,CCNF,EIF4A3,METAP2,RPL22,SEC63,NDN,COPE,RPL13A,MAK16,OTUD6B,RPL29,ZNF397,B3GNT2,TENT5D,RPS11,SART3,EZH2,CHMP4C,RPS24,MRPS11,SLC25A5,TRIP4,RPS27A,SAR1B,G3BP1,TNF,GNL1,TRIM37,MAP3K14,VPS26A,MRPS35,MRPS26,RB1CC1,RPL23,WDR12,GJA1,MAP1LC3A,HP1BP3,RPLP1,RPLP2,RPL8,RPL9,FOLR1,PHB1,NOP58,RPL7,H1-5,EMC9,G3BP2,CMAS,ARL6,NOP53,ZNF668,CUL3,CUL2,NOP16,HSP90AA1,RPS5,RIT1,BRCA1,RPL37A,SEC61B,RPS9,ARF1,ZNF22,EIF3K,RPL19,PRRC2A,PRDX2,RPF1,RPL35,RPL7L1 |
| 2.491e-14 | -31.32 | HDLBP (high density lipoprotein binding protein) | protein interactions | 3069 | 821 | 329 | 19454 | 5460 |
GGCX,XPOT,RACGAP1,USP14,PPP1CC,DNAJC8,NONO,FBXO7,FLRT3,VIRMA,RPP25L,NDN,LDHA,RAB14,MAGOHB,COPE,PTCRA,RPS20,RTRAF,TNFRSF1B,ENO1,POP7,CCNF,RPL26L1,TMOD1,STOM,METTL14,CHMP1A,TOX4,SPMIP6,SF3A1,CPSF4,PSMC4,ATG16L1,AATF,NHP2,FBXW7,HMGB1,GTF2I,CCDC106,SQSTM1,SIRT7,FADS2,RPA3,TOPBP1,CRBN,SUV39H1,LRRC40,ATP1B1,SPATS2L,GRSF1,ERCC3,CWC15,AKAP17A,THOC1,TOP1,RPL35A,SEC23A,EEF1AKMT3,KRR1,HRAS,SRP14,SRP72,ILF2,LLPH,LBR,EEF1A1,CD2BP2,CHKB,CCT5,YTHDF2,CCDC47,SMN1,RIGI,ARF4,THRAP3,TTC4,PAK1IP1,SNAP23,PC,RING1,NKRF,TMED1,TCOF1,BRCA1,LMNB1,FYTTD1,GGH,RBM15B,RIOK2,SMARCE1,TMED4,PYCR1,PRRC2A,RPL19,GNB1,UMPS,TENT5C,DYNLL1,AKR1C2,SNRPD2,SNRPD1,RAN,ARF1,CPSF1,FAU,EMC9,LARP4B,PPP1CB,EHD1,RFXANK,ACTL6A,UNC45A,G3BP2,FTL,FBXO30,SKP1,COIL,CDSN,YTHDF1,HADHA,C1D,CCDC86,UPF3B,THOC3,HAX1,LYZ,RSBN1L,DROSHA,CSTA,DDX23,TRA2A,VPS26A,UBXN6,CLPX,PRPF19,DHX15,TMEM237,WIF1,SRSF10,SPTAN1,MRTO4,THOC2,GTPBP1,SART3,SNRPE,RPS11,EZH2,GTF2E2,DCUN1D3,LGR4,GFPT1,NEU1,RAF1,MARCKSL1,FEN1,SSRP1,RFC2,UBE2A,PSMD12,GTF3C3,S100A10,BPGM,UFM1,DHX16,G3BP1,BAG2,SRSF7,SRSF8,PCNA,ZC3H7A,ZYX,MORC2,TRIP4,UBE2H,ALKBH5,ATP1A1,CFL1,CEP85,RAB2A,SMARCA5,SRPK2,SRC,PPP1R10,BUB3,GTF2H2,RBMX2,SF3B6,RPS3,PSPC1,UQCRC2,LUC7L3,TFIP11,ZNF326,RPA2,CFTR,SNRNP27,CDC42,GTF3C4,SPTBN1,SNX33,OR51M1,TRIM3,PML,TMEM263,SEPTIN6,BAP1,UGDH,CDK12,SMCHD1,SNRNP70,NXT2,SMAD4,GAPDH,TPM3,TMA16,COPS5,CSNK2A1,RBM17,KARS1,DPP4,ACOT8,CMSS1,CDC5L,DKC1,RBM42,TMPO,CPNE1,TMED9,RPS16,FZR1,RAP1B,ALYREF,ACSL4,SYNCRIP,GNAI3,RBM34,CBX3,TFCP2,WBP11,TP53,STRBP,KBTBD4,TMEM33,CDC40,MRPS33,DHX9,MRPS18B,ZNF451,RCL1,THOC6,DNAJB6,MCAT,OSGEP,RBM27,FTSJ3,CHTOP,S100A11,CYP1A1,CKB,CIRBP,SNRPB,CPSF2,MYC,PSMB6,CBX5,TAX1BP1,ZCCHC7,SNRNP40,MATR3,STAT1,USP16,ADH1B,VDAC2,LMBR1L,PIH1D1,GLRB,FBXO42,PABPC5,STAU1,SSR3,PHB2,FXR2,SRSF2,RAB5A,HSPA8,SF3B1,SPECC1L,XRCC5,DDX39B,PYM1,RFC4,HSPB1,DRG1,SMAD9,DRG2,AGR2,CTNNB1,QPCTL,NGDN,SHC3,DKK1,WWP2,DIRAS2,LAMP2,GSTM3,TMEM97,PEG10,TCP1,SUMO2,SNRPD3,LYAR,RAB1B,RBM5,SRSF1,FUBP3,TNIK,SMARCB1,SMNDC1,PDHA1,TOP3B,RUVBL1,VDAC1,DCP2,RUVBL2,EWSR1,CCT8,RBM3,PABPC1 |
| 2.590e-14 | -31.28 | RPL12 (ribosomal protein L12) | protein interactions | 6136 | 365 | 170 | 19454 | 5460 |
RPS14,CDC42,CFTR,CDK7,JUP,RPA2,GRM2,METTL14,HEXIM1,RPL26L1,RPLP0,RPA3,RPL27,BAP1,KIN,RNF113A,SQSTM1,NPM3,FBXW7,HMGB1,RPL4,HSPA5,RPL7A,RPS17,TUFM,PPP1CC,USP14,MECP2,RC3H2,STK24,UBE2H,CCNF,OPTN,RPS3,METAP2,PRKRA,RPS20,PTEN,RPS12,COPE,RPL13A,RPL10L,VIRMA,RPL22,UBL4A,FBP1,TP53,RPSA,EEF1A1,RPL15,TFCP2,TNFAIP8L1,LLPH,DNAJC2,SRP72,RPL3,RPL23A,HUWE1,VRK1,MEPCE,FBXO25,MRPL22,RPS13,RPL17,GRSF1,MOV10,HDAC6,COPS5,CD81,API5,RPL24,SNRNP70,RPS2,RPL10A,EFNA3,RCHY1,RPL32,CAND1,RPS16,RPL35A,DNAJC1,FZR1,RPS27L,RBM42,TMPO,CDC5L,RPL27A,PAFAH1B1,MRPL12,EMC9,PPT1,PIH1D1,DDX39B,RPS28,HSPA8,AKAP1,RAB5A,STK26,C1D,UFL1,STAU1,GPC1,G3BP2,ACO2,MYC,CUL3,CUL2,ZNF668,BTF3,BRCA1,ICAM1,RPS26,RPS5,RIT1,H1-1,FAU,CMTR1,RPL37A,RPS9,SEC61B,PRDX2,RPL35,LGALS3,RPL10,RPL19,B3GNT2,MAGEB10,SOX2,RPL29,EEF2,MSX2,RPS7,EZH2,RAB4A,PDHA1,RPS11,RPS23,RPL18,RPL31,EWSR1,RPS24,KRAS,G3BP1,TNF,VDAC1,S100A10,TRIM37,UBE2A,RPS4X,CNOT2,WWP2,RPL6,CTNNB1,DDRGK1,NCK1,AGR2,DICER1,RPL23,BCL2L1,DRG1,RPL8,RPL9,FOLR1,PHB1,EED,RPLP1,RPLP2,RPS10,RPL7,DHX15 |
| 2.666e-14 | -31.26 | VRK1 (VRK serine/threonine kinase 1) | protein interactions | 7443 | 269 | 134 | 19454 | 5460 |
RPA3,RPL27,NBN,BANF1,RPS15,RPL4,ATG16L1,RPS14,MND1,SNRNP27,RPA2,BORCS5,RPLP0,MACROH2A2,RPS3,ZNF330,RPS20,MACROH2A1,RPL13A,SRPK2,RPL22,TNFAIP3,RPL7A,RPS17,RPL26,USP14,RACGAP1,NCAPG2,IGF2BP1,RPL3,RPL23A,DHX9,H3C1,VRK1,RPS13,RPL17,H2BC14,MDC1,H2AC6,ATP5PB,TP53,RPL15,IZUMO1,CBX3,NUPR1,RNF8,RPL12,CD274,SYNCRIP,SRP14,RPL32,ALYREF,RPS16,RPL35A,PRELID1,SLAIN2,H2AC14,LAMTOR2,SETD5,SMIM12,RPL24,RPS2,RPL10A,BRD3,PYM1,XRCC5,HSPA8,DDX5,HADHA,COIL,RPL27A,ZBTB42,FAU,RPL37A,RPS9,MATR3,LAMTOR3,RPL35,MED17,TUBB,RPL10,RPL19,BORCS7,HNRNPC,RPS29,LAMTOR1,H2AZ2,LMNB1,H1-10,CHTOP,CYP1A1,OSGEP,RPS26,RPL31,HSPD1,TOP2B,HNRNPA2B1,TRIM21,RPS24,SRSF7,HNRNPF,KRAS,RPS4X,RPL28,RPS27A,SSRP1,GOLGA7,AHCYL1,TRMT1L,FEN1,TRAF2,JUN,RPL29,GTF2E2,RPS7,SF3B5,RPS11,RPS23,SNRPE,RPL18,RPL8,RPL9,EED,HP1BP3,RPLP2,RPL7,HMGA1,PRPF19,RPL6,SLC38A7,HNRNPA1,HNRNPD,PEX3,RPL23 |
| 2.673e-14 | -31.25 | CMTR1 (cap methyltransferase 1) | protein interactions | 23070 | 205 | 109 | 19454 | 5460 |
H1-5,EIF4B,USP39,DDX5,EP300,SF3B1,XRCC5,G3BP2,WASF3,STAU1,EEF1G,FXR2,RNF40,SAMHD1,HNRNPC,CUL3,HNRNPAB,RIT1,RPS26,LMNB1,CIRBP,RPS9,PRMT5,CMTR1,APEX1,RPL19,RPL10,MED17,RPL35,MATR3,RPS7,GTF2E2,SUPT5H,RPS11,RPS24,LDLRAD4,ABCF1,PABPC1,HNRNPA2B1,SRSF4,RPL28,RPS4X,ASF1A,KRAS,G3BP1,NT5C2,HNRNPA1,PRPF19,PRDX1,HMGA1,RPL23,PPM1B,DDX23,RPLP2,SRSF1,RPL9,CCDC71,DHX15,CCAR2,HNRNPL,RPS10,EIF2S1,SETD3,SPTBN1,LMNA,RPA2,PML,RPL27,RPA3,EIF5B,RPL26,RPS17,RPL7A,UBE2H,EIF3G,EIF2S2,RTRAF,EIF4A3,LIG3,CCNF,RPL13A,RPL15,TP53,ILF2,DHX9,RPL23A,RPL3,MAP1B,PTGES3,EIF3E,RNF20,RPS13,HNRNPK,KPNA2,MOV10,RPL10A,RPS2,SMCHD1,ALYREF,RPL32,SYNCRIP,RPL12,CDC5L,TMCC2,TSC22D3,THOC1,TOP1,RPL35A,RPS16 |
| 2.750e-14 | -31.22 | RIGI (RNA sensor RIG-I) | protein interactions | 23586 | 1739 | 626 | 19454 | 5460 |
ZDHHC16,UQCRC1,SLC35E1,TIMMDC1,RIMKLA,PDE8A,DRAM1,STAMBP,HNRNPH3,METTL14,CZIB,OSER1,GP9,AP1AR,DCTN4,RTN4,TCEA1,PRKCB,GID8,FAM222B,IDH3A,HELLS,INPPL1,FBXW7,IRF7,YKT6,NAA60,ZNF687,STK38L,SMAD2,SDF2L1,RPS12,DNASE1L1,RNF122,EIF2AK2,KCNMB1,VIRMA,GNAI2,NREP,COPE,NDP,PNP,CD2BP2,TAF1D,FAM13B,CCT5,TRIM6,ITGB8,MRFAP1,TCOF1,RIGI,H2AC6,PAGR1,CDC42SE1,FRMD8,ERLEC1,SETD5,FAM133B,IRF9,BRD3,SMG9,ECD,POR,MUL1,BOK,ST6GAL1,TREML1,TFE3,SMAD3,CWC15,MDM2,SCG2,TSC22D3,RPL35A,AGTRAP,ELOVL1,FERRY3,VPS18,VAPB,PSMB7,EMG1,RABAC1,TXNL1,EXD2,FAM168B,MIR24-1,ATP6V1G1,CCND3,NOP53,CYFIP2,CAPG,ELMOD2,ZNF250,NIBAN2,TM2D2,PFDN2,PPP1R16A,SNRPD1,SNRPD2,ENO2,CNOT6,CD86,S100A6,FCHSD2,MAD2L2,SELL,PGPEP1,CD40LG,SIAH1,ACTB,B4GALT4,REEP4,MED17,NFE2L1,PPP2R1A,JUN,FAF2,GABARAPL1,NEU1,CSNK1E,RBM12,WBP1L,RPS11,STX12,NDUFS6,GDAP1L1,PRPSAP1,MAEA,MAP3K11,ZYX,GPAA1,OVOL1,FLOT1,SEMA4C,CDK20,DHX16,WDR19,ZNF207,HNRNPA1,PCNX1,ISX,SIGLEC5,RAB32,COTL1,DICER1,RB1CC1,TERC,HAX1,PEDS1,DROSHA,ATP6V1A,SNX17,PLEKHO2,IFIT2,MRTO4,PSMB4,SPRED2,DHX15,PPIA,MAFG,SNX22,HCST,FBXL19,CHST7,LUC7L3,CSNK1G3,GPR35,HBB,FGFR1,SSR1,DERL1,GFM1,SMG5,MIR132,PGK1,RNF34,LRP10,IRF3,PML,NLE1,TUSC2,CLDND1,ST8SIA4,ST13,OGG1,MTPN,CFL1,SUGP1,RGL2,SMARCA5,TRIM32,AKT1,RIC3,TRAF7,B4GALT1,SLC25A39,ACP2,CLCN6,EGLN2,TXNDC12,GTPBP8,KIF1C,IMP3,SLC25A24,SURF4,MIR26B,BHLHE40,ADRA1A,PIK3AP1,MEPCE,EDEM2,HNRNPK,TPM3,POLR3GL,USP3,TSNAX,TNFRSF14,TAF9,MIR484,ADD1,ITGA6,PDE1B,RASGRP2,ESD,KMT5B,CNIH1,LMO3,TOM1L2,IL6ST,FGF17,ACSS2,CSNK1A1,LACC1,GSTM2,DDX5,DR1,MIR30A,CCNI,TAPBP,SF3B1,PEBP1,CCDC9B,MIR30B,PHB2,FXR2,SLC31A1,NDUFS2,SNRPB,BAG3,CUTA,BTF3,HNRNPC,HNRNPAB,MYC,COX6B1,ATP5MC3,OAZ1,FBXW11,RPS6KA4,CIRBP,PELI3,CCT2,MIRLET7B,ATXN1L,MIDEAS,LMBR1L,FAIM,VEGFA,DDIT4,TVP23B,STAT2,MATR3,FOXJ3,EEF2,NCSTN,H1-3,TMBIM1,ANAPC13,DHX38,OARD1,TAF10,RPS23,ISG20,PDHA1,EWSR1,MIR183,OAS1,ABCF1,LSM14A,BCL7B,CYP1B1,CBLL1,PFDN1,TBC1D10C,TENM3,XPO1,PTDSS1,RPL6,PFDN5,WWP2,BAZ1B,CD52,SPHK2,ASB7,CBL,DENND6B,AK2,WDR82,DUSP6,GYS1,KCTD20,FHIP1B,CHI3L1,GLRX,CYP4F8,ELP3,MX1,MYL12B,RBFOX2,PSMC4,PITPNA,IFRD1,LEP,TM9SF1,HSP90B1,PTP4A2,SQSTM1,ARPC2,MAVS,NXPE3,MTDH,GPX4,MGAT4B,SS18,GABARAP,SLC5A6,DGCR8,GTF2I,PPP1CC,USP14,GMPS,CSK,NDUFB10,STK11,ECRG4,UBE2I,WDR45,PRKRA,CYRIB,FBLN5,SMAP2,EZH1,MIR16-1,STUB1,SMAD5,DDAH2,RPL13A,CD47,CEBPE,ABHD17A,LDHA,ZNF622,MGAT1,PCED1B,MLLT6,CTDSP2,MAP1LC3B,TBK1,POMT2,CASK,SEMA7A,GABPB1,SEPTIN7,KATNAL1,MSH6,PRDX4,MDC1,SOCS2,TICAM1,OLA1,APH1A,CCL2,LSM4,SEM1,METTL24,ABRACL,HDAC6,AMT,CIDEB,FGR,MPHOSPH10,SEC23A,UBP1,SRPRA,H2AZ1,NOP9,TRAPPC6B,DBT,PPP1R18,EHD1,IDH3B,RAB37,PRKAB1,PSRC1,PPARG,TEX261,HADHA,NUP50,NUBP2,HRH3,SAT1,WBP2,FBXW4,CXCR4,FTL,MIR877,ATAD1,LZTFL1,MIR454,ZDHHC24,MCM3,MCM4,RNF40,GRB10,CUL3,MRM2,SLC35C1,SLC35E4,NTRK3,FCER1G,TBC1D16,SERINC1,AP2M1,FAM43A,ELK3,PELO,TNPO3,TMCC1,CHP1,RPL7L1,TULP3,MAK16,KHDC4,E2F4,GTPBP1,SF3B5,CTSA,FHL3,GPSM3,COX8A,ERP29,ATP6V0B,OSTM1,RNASEH2C,MORC2,MEF2C,ANP32B,SRSF4,GCA,ADO,G3BP1,LAMB2,LAT2,MMUT,STOML2,MARCHF5,TAF7,CLPX,PPP3CA,LST1,TMEM164,C2CD2L,UBE2D1,RPLP1,IGBP1,CBFB,SLC43A2,THOC2,OS9,RAB11B,TMEM170A,SERINC3,SNX1,COPS7B,POLR3F,CREBZF,XBP1,MIR152,CCNH,RETN,BLCAP,TRIM36,STAT6,ACACA,GSTP1,PRKCA,VPS54,GIT2,BTG2,VPS4B,MIR10B,APMAP,UGDH,MARS1,TOMM20,KDM1A,UBE2K,SLC6A6,SLC6A4,TIA1,MIR375,GABRB3,PTPN11,SUB1,CALU,SNX5,UHMK1,ATP1A1,CCDC174,TRIM23,LSM6,EIF3G,ZNF655,PLCB2,UBN1,SRC,MYG1,PRKCE,ADRM1,ARHGAP12,CDK4,GCHFR,MTCH2,CD14,MSRB1,SESN2,TAF2,NHERF1,ARPC3,TMEM165,TFCP2,IDH1,ERO1A,PCYOX1L,NOSIP,CYTH2,FKBP8,PHYKPL,RBCK1,TSEN34,FAM20C,PGAM1,USP15,CDK12,DELE1,RGP1,NUDT9,MCL1,COX4I1,COMT,HCLS1,SURF6,CD99L2,TMPO,RBM42,PRELID1,SELENOI,ILVBL,PLSCR3,FCHO2,RPS16,IFRD2,PIH1D1,SIGMAR1,MXD1,DDIT3,FOS,MRPS7,UBE2D3,CCDC85B,CDKN2D,CCL24,PAPOLA,EPS8,GTPBP2,DNAJB6,H1-10,NFKBIB,EFHD2,NIPA2,ATP5F1B,MIR190B,ISG15,ARFGEF1,UBL5,STBD1,RPL18,ADCY3,MTA2,SEC61G,NFKBIL1,TRIM11,ICAM3,GALC,RTCB,FBXO11,CCT8,RBM3,CD83,NUP42,TBC1D5,CBR4,YWHAB,SLC39A13,DUS4L,FOSL2,FAAP100,MAGED2,S100A8,TNIK,MIR331,MACROD1,CYTH4,TRIR,ASIC1,LSM5 |
| 2.808e-14 | -31.20 | regulation of cytokine production | biological process | GO:0001817 | 863 | 356 | 18204 | 5365 |
MIR15A,LGR4,PDCD4,IFNG,CD47,IL17F,PIK3CG,ATF4,PDE4B,CD200,TRIM21,MIR140,LEP,CD40LG,CD58,SRC,ANGPT1,IL18,SRGN,MOG,MIR874,IL23A,SEMA7A,MIR181C,BMPR1A,PPM1B,TLR1,IL15,TICAM1,TLR8,IFI16,CAPN2,IRF1,PQBP1,CCL1,OSM,AFAP1L2,PIK3R1,CUL3,SETD4,MIR100,ASB1,SELENOK,TUSC2,GPAM,TRIM32,MIR920,SERPINB1,SMAD3,MIR24-1,MIR101-1,SPTBN1,CD2,VSIR,NFKBIL1,FCGR2B,CD40,SYK,CLU,HILPDA,MIR205,NLRP1,ARG2,MIR16-1,NFKB1,PML,IGF2BP1,CLEC9A,CHI3L1,MIR378A,CYRIB,TBK1,RNF26,ZBTB39,TLR5,CCL19,SFTPD,TRAF6,MIR373,TLR2,ZBTB25,ZNF287,CYP1B1,TICAM2,MIR222,MIR181D,CD2AP,CD86,PYDC2,MIR107,ZBTB2,AGPAT1,RSAD2,CSK,IL6,ELF1,FGR,POLR3B,MIR185,DDX1,FCER1G,IL12B,FOXP1,MACIR,STOML2,IFNGR1,FLOT1,PPARA,PELI1,PRNP,CD274,FOXP3,HSPD1,PNP,MIR197,UCN,POLR3F,MIR210,BAP1,CD36,MIR129-1,CD80,ANXA4,CLEC6A,MIR204,ZBTB33,NMI,RIGI,INHA,IFNA2,MIR21,LILRA2,TIA1,MIR383,RGCC,TNFRSF1B,PLCB1,TLR9,TMEM106A,MIR877,TNFAIP3,HYAL2,GSTP1,MIR675,IGF1,PPP1R11,SELENOS,TANK,SMAD4,RNF128,TLR6,TGFB3,MIR136,IL1B,MIR182,DEFB114,CD34,KPNA6,LACC1,ACP5,STAT1,MIR125A,BST2,TIRAP,JAK2,SOD1,IL2,MIR130A,MIR221,MIR155,MIR206,EIF2AK2,CD14,KIT,XBP1,MIR320A,MIR34A,IL13,IL21,CLEC7A,IDO1,DDIT3,TRIM27,TLR4,TOMM70,KLF4,MIR147A,MIR590,PTPN11,SCAMP5,FGFR1,MIR26B,IL7,ITK,EZH2,CHRNA7,MIR195,B2M,EGR1,GAPDH,TRIM15,RAD21,MIR28,KPNA2,LUM,PTGER4,MIR106A,PRKCQ,GPNMB,HOMER3,UFD1,TSPO,ZBTB6,KLHL22,F11R,LY96,TRIM6,RPS3,PHB1,FCGR2A,NMBR,CX3CR1,TRAF2,MIR145,CX3CL1,ROCK2,IL10,MUL1,XCL1,TWSG1,ADIPOQ,TNF,PYCARD,HRAS,MIR361,AGER,LURAP1,IL1RAP,BATF,MIR98,EPHA2,HFE,BCL6,HMGB1,CGAS,NLRP2,MIR338,ZBTB45,MIR105-1,JPH4,SPHK2,TNFRSF14,PDCD1LG2,MIR657,IRF4,F2,CCR2,MIRLET7C,AIF1,NLRP3,XAF1,CEBPG,MIR17,MIR214,MIR142,HSPB1,FRMD8,AKAP12,DEFB124,TLR3,MIR106B,G3BP1,GPSM3,IL6ST,CSF2,BTN2A2,HSP90AA1,IRF3,IL12A,HTR2A,MIR132,DDT,BCL10,RPS6KA4,MIR194-1,LILRB1,ATP6AP2,SASH3,CCL3,CD83,MIF,RAB1A,CD28,MAVS,ZBTB17,FURIN,CHID1,IFNB1,CPTP,TYROBP,CD4,NLRP9,CD81,LILRB4,MIR146A,PSEN1,MIR149,CD46,MIR324,MYD88,MIR31,BRCA1,NPTN,IL4,MIR504,IFIH1,IL20RB,SOCS5,RUNX1,OTUD7B,LTB,CRYBA1,MAP2K3,IL1A,TGFB2,MIR144,MIR192,PLD3,UAP1,MIR152,CCR7,ISG15,DHX9,PTPN22,MIR488,TRAF3IP3,OAS1,LTA,IRF8,MIR708,ZBTB26,CD200R1,MIR200C,NLRP6,TLR7,IRF7,LITAF,BANF1,MIR215,SNAI2,DICER1,NDFIP1,PAEP,IL1R2,MIR20A,GHRL |
| 2.827e-14 | -31.20 | RPL24 (ribosomal protein L24) | protein interactions | 6152 | 349 | 164 | 19454 | 5460 |
UFL1,STAU1,G3BP2,RPS28,XRCC5,KCTD12,EMC9,EIF4B,PIH1D1,RPL27A,NOTCH2,TIMM13,RPL35,PSMD6,RPL10,RPL19,RPL37A,SEC61B,RPS9,BRCA1,ICAM1,RPS26,RPS5,RIT1,MYC,SFN,CUL3,CUL2,SAMHD1,PDE4B,BTF3,PSMD1,CHCHD2,EMC8,KRAS,TRIM37,RPS4X,RPS27A,SAR1B,RPL31,RPS24,EZH2,CHMP4C,RPS11,RPS23,CYB5B,RPL18,B3GNT2,SOX2,ISG15,RPL29,RPS7,RPS10,RPL7,RPL8,FOLR1,RPL9,PHB1,EED,RPLP1,RPLP2,SKIC8,AGR2,POU5F1,RB1CC1,RPL23,DRG1,MAGOH,WWP2,RPL6,XPO1,MAP3K14,DDRGK1,RPS15,KDM1A,HMGB1,FBXW7,RPL4,LSM8,HSPA5,RPA3,RPL27,BAP1,SNAPC1,PML,RNF113A,RPA2,WWP1,METTL14,HEXIM1,RPLP0,UBE2M,KLF4,GTF2H4,RPS14,EEF1E1,UBA52,CFTR,NDN,RPL13A,RPL10L,SMURF1,VIRMA,RPL22,CCNF,RPS3,METAP2,EIF4A3,PRKRA,RPS20,RPS12,RC3H2,TRIM23,PTTG1,UBE2H,RRP7A,RPL7A,RPS17,RPL26,USP14,PPP1CC,AR,VRK1,MEPCE,RPS13,RPL17,FAF1,RPL3,RPL23A,TFCP2,SRP72,UBL4A,FBP1,RPSA,TP53,EEF1A1,MAP2K3,RPL15,RPL35A,CAND1,RPS16,FZR1,RPS27L,CDK9,RBM42,TMPO,RPL12,SYNCRIP,ARL10,RPL32,RCHY1,ARL4D,PSMB1,TUBG1,RPL24,SNRNP70,RPS2,RPL10A,ENY2,EMC4,HDAC6,COPS5,CD81,API5 |
| 2.995e-14 | -31.14 | RAB | smart domains | SM00175 | 149 | 83 | 9717 | 2575 |
RAB39B,RAB1A,RAN,RHOU,RAB13,RAP2B,RABL3,RHOJ,RAB9B,ARF6,RND2,MRAS,RASL10B,DIRAS1,RASL10A,RAB30,RHEB,RAP2A,RASL12,RERG,ARF1,RAB40AL,RAB2A,RALA,RASL11A,RAB31,RAB11A,KRAS,RAB1B,AGAP2,RAB23,RAB33B,RAB18,ARF4,TRIM23,RAP1B,RAB35,RAB8B,ARL4A,NKIRAS1,RHOB,DNAJC27,RAB11B,RHOG,RAB3B,RAB9A,RAB5A,RAB19,RAB32,RAB28,RHOBTB1,RAB3C,HRAS,RASD1,RAB29,RAB4A,RIT2,RND3,RAC2,DIRAS3,RAB27A,RAB5C,RHOH,RABL2B,NKIRAS2,DIRAS2,RAP2C,RAB3D,RAB6A,RAB22A,RAP1A,RAB33A,CDC42,RAB37,ARL4D,RALB,AGAP1,ERAS,RIT1,RAB3A,RAB14,RRAS2,RAB6B |
| 3.096e-14 | -31.11 | RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase) | protein interactions | 51493 | 352 | 165 | 19454 | 5460 |
RFC4,DDX39B,EP300,HSPA8,STAU1,PAFAH1B2,FXR2,UFL1,MIR106A,SAP18,PPT1,LARP4B,NUFIP2,EIF4B,MIRLET7B,TENT5C,MATR3,ERH,RPL10,MIRLET7D,CUL2,CUL3,APOBEC3B,MYC,UFD1,MIR98,BTF3,PSMD14,FBXW11,LAMTOR1,FYTTD1,NSA2,RIT1,MIR363,MIR9-2,ABCF1,PABPC1,MIR206,MIR155,VDAC1,KRAS,G3BP1,RFC2,POLDIP3,RPS4X,RAF1,RPS7,MIR222,SOX2,CAAP1,CHMP4C,PLS3,MOB3C,MTA2,MIR7-2,PHB1,DNM2,MIR141,MIR214,RPLP1,MIR9-1,FAM98A,MIR143,WWP2,DDRGK1,XPO1,HNRNPA1,ATG7,YWHAG,YWHAH,MIR29C,AGR2,MIR31,WDR12,MAGOH,MIR140,MIR1-1,DCAF11,MIR221,DDX1,POU5F1,MIR205,SIRT7,RPL27,BAP1,MIR10B,RPA3,MIR34C,RNF113A,MIRLET7I,LSM12,FBXW7,MIR7-3,MIR107,MIR29A,PPP1R8,MIR34B,CDK7,MIR1-2,EIF2B3,ZNF326,RPA2,KLF4,MIR7-1,UBE2M,MIR21,HEXIM1,RPL26L1,PSPC1,MIR16-1,CCNF,RTRAF,CIAO1,AR,CCDC22,RC3H2,MIR145,SPOP,UBE2H,MIR200A,HSD17B10,DHX9,MIR9-3,ABCE1,ZC3H11A,CDC40,RIGI,SEPHS1,MIR16-2,MIRLET7C,YTHDF2,MIR15A,MIR200C,EEF1A1,MAP1LC3B,ACTR2,MIR20A,MIR17,NUPR1,RNF181,ILF2,RCHY1,MIR106B,MIR25,DLGAP4,EIF2B2,THOC1,MIRLET7G,FZR1,RPS16,CAND1,CDC5L,TMPO,CDK9,MIR429,EMC4,MTMR12,API5,COPS5,SNRNP70,H2AC4,CRBN,MIR34A,USP15,RPS2 |
| 3.227e-14 | -31.06 | RPL35A (ribosomal protein L35a) | protein interactions | 6165 | 363 | 169 | 19454 | 5460 |
RAP1B,RPL12,PTPN1,RPL32,RCHY1,UBP1,CAND1,RPS16,SPPL3,FZR1,RPS27L,API5,LRRC40,DPP4,ENY2,RPS2,USP15,RPL10A,BRD3,SMCHD1,RPL24,SNRNP70,RPL3,ZC3H11A,RPL23A,ABCE1,NSDHL,PPP1R12A,MEPCE,RNF20,RPS13,RPL17,MDC1,RIGI,CTNNBL1,VRK1,RPL15,KBTBD4,FBP1,RPSA,RAP1A,HBP1,RNF181,SRP72,CBX3,RBM34,DNAJC2,PRKRA,RPS20,RPS12,VAMP3,CCNF,RPS3,EIF2AK2,METAP2,CYRIB,SCML2,RPL22,DUSP3,RPL13A,DNAJC8,NAA50,RPL7A,UBE2H,PSMG3,CHORDC1,RNF113A,MAVS,RPA3,DDX46,RPL27,BAP1,NLE1,AATF,HSPA5,RPS15,WDR3,RPL4,FBXW7,H2AC13,FBXL19,CFTR,UBLCP1,KLF12,CDK7,SF3A1,RPS14,UBA52,PPP1R8,RPL26L1,RPLP0,TMOD1,OXSR1,RPA2,RPRD1B,METTL14,S100A8,RPLP2,RPL8,FOLR1,RPL9,PHB1,RPS10,RPL7,CTNNB1,MAP3K14,DDRGK1,WWP2,RPL6,NDUFB8,RPL23,DRG1,NCK1,AGR2,RPL31,TRIP4,RPS4X,RAD21,IMMP2L,SAR1B,LASP1,KRAS,XPNPEP1,TRIM37,OTUD6B,SOX2,KIF2A,RBM12,FEN1,B3GNT2,NAA15,RPS11,RPL18,EZH2,RAB4A,PTRH2,CHMP4C,GTF2F1,RPS9,CYB5R3,CMTR1,RPL19,RPL10,RPL35,ACTB,RPL39,BTF3,MYC,HNF1B,TBCE,CUL3,ICAM1,RPS5,HTRA2,ZMPSTE24,ATG3,RAB5A,PYM1,FOS,HSCB,UFL1,STAU1,ETF1,EFHD1,RPL27A,MTF1,PIH1D1,EMC9,MAP2K1 |
| 3.303e-14 | -31.04 | EBNA-LP (nuclear antigen EBNA-LP) | protein interactions | 3783746 | 154 | 88 | 19454 | 5460 |
RBBP4,TUBB,EGLN2,ACTB,PSMB6,RPL10,SNRPB2,RPL22,STUB1,TUBA1B,SNRPD2,RPS9,H1-10,HSP90AA1,XPOT,DNAJB6,PYCR2,RPL7A,HNRNPAB,LDHB,SEC13,RPS17,ATP5F1A,RPL26,BAG3,MLF2,PCCB,NONO,HNRNPA0,RPS15,PHB2,GRPEL1,HSPA5,SNRPA,IDH3A,XRCC5,HSPA8,SF3B1,P4HA2,DDX5,CDK1,FKBP14,WDR77,RPS14,RPL27A,IDH3B,EIF2S1,RPS16,TMED9,RPL7,RPS27L,RPL12,RPL8,SSBP1,SYNCRIP,RPL9,SRSF1,RPL24,AKAP8L,HAX1,HNRNPD,RPS2,RPL23,HSPB1,CLPX,HNRNPA1,RBBP7,CSE1L,RUVBL1,HNRNPK,RPS4X,RPS13,RFC3,RPL17,CAPZA1,RPL31,HSPD1,SLC25A5,HNRNPA2B1,RUVBL2,DHX9,BAG2,NME1,RPS11,RPS23,RPL18,GCHFR,H1-3 |
| 3.377e-14 | -31.02 | RPN1 (ribophorin I) | protein interactions | 6184 | 778 | 314 | 19454 | 5460 |
LRRC8D,RPA3,NCDN,RHOU,IDH3A,FADS2,SYVN1,SPCS2,MTDH,RTN4,YKT6,CERS2,SLC7A1,DAD1,TMEM209,ATG16L1,RABL3,PSMC4,RBFOX2,ARHGAP1,TPT1,SEC22B,ST7,LMNA,TOX4,HSP90B1,PICALM,GRM2,TMX4,METTL14,SLC12A2,PDCL,PIGW,CCNF,SCAMP2,METAP2,RHOJ,UBB,TECR,VKORC1L1,VIRMA,SEC63,ATP5F1A,FBXO7,TUFM,HMOX2,TMEM106C,TXNIP,CDC73,DNAJC19,RAB1A,NSDHL,PPP1R12A,RPL23A,EMC2,PC,IGF1R,NSG1,DNAJC30,FBXO25,CCDC47,FBP1,FAM13B,URAD,LBR,DDX39A,SLC29A1,PTPN1,HACD3,SRPRA,RCHY1,MYBL2,HSD17B11,LMBRD1,ASB11,ARF6,CDK9,ZBTB2,EI24,TMEM199,ATP5MG,SLC25A46,HDAC6,LAMP3,HM13,POR,TIAM1,ESYT1,OSBPL8,RAB3A,DNAJC3,HACD1,NUBP2,UCHL3,ATAD1,PXMP2,COIL,PSMC1,G3BP2,DNAJC22,PGRMC1,NOTCH2,TOR1AIP2,RND2,OTULINL,VAPB,KLF3,SLC25A3,ARF1,PIGK,CYB5R3,FZD6,RMDN3,GPR89A,SEC61B,RBBP4,RPL35,REEP4,ABHD12,VEZT,KDSR,CUL3,SLC41A3,TOMM40,RHOB,LMNB1,NTRK3,DHRS1,RIT1,ILK,VMP1,SLC25A5,TMT1A,SLC39A7,SCD5,G3BP1,EMC8,TRIM37,RETREG1,RAF1,B3GNT2,MACO1,FAF2,PPP2R1A,LGR4,STIM1,EZH2,RPN1,CHMP4C,CYB5B,PLD3,PHB1,GJA1,ATP6V1A,CYB5A,KCTD10,EGLN3,OS9,PRPF19,PTPN5,ICAM2,CDK5RAP3,RHOG,C2CD2L,RB1CC1,TEX264,DERL1,RAB9A,BCL6,HSPA5,GABRA1,CDC42,CFTR,RPA2,USE1,SSR1,FGFR1,HEXIM1,UBE2M,LEMD3,CYC1,UQCRC2,ATL1,PSMC5,SGTA,CTSB,TLCD2,ADRM1,PLAGL1,SUCLG2,SLC25A1,RAB2A,GSTK1,TIA1,GORASP2,SLC6A6,DNAJC10,ATP1A1,UBE2H,CALU,RUSF1,MAP1B,STX18,YIF1A,BCAP29,NUP107,TMEM33,SRPRB,SLC6A8,MEPCE,FKBP8,UBL4A,PREB,RPSA,INSIG2,TP53,MTCH2,UBIAD1,SURF4,TFRC,TFCP2,FURIN,PSMC3,COQ8A,CD274,STT3A,SYNCRIP,CAMLG,SLC39A10,RAC2,ARL6IP5,DNAJC1,LMAN1,TMPO,SLC38A2,CDC5L,DPP4,DHRS7,EDEM1,FAM20C,COPS5,TUBG1,AGPAT1,DDX39B,JAGN1,TMEM106B,HSPA8,HDAC5,EP300,RAB5A,AKAP1,EMC1,UFL1,SSR3,STAU1,ADRB2,CERS6,TOMM22,BET1,SEC62,EDEM3,UBAC2,PPT1,CAV2,FDFT1,CSNK1A1,VDAC2,LMBR1L,DLST,GGT7,ATP6AP2,TMEM38B,OST4,MYC,PSMD14,ZMPSTE24,CYP2C9,TMEM87A,CCT8,PDIA6,TRIM11,KRAS,VDAC1,STBD1,NETO2,DNAJC25,SOX2,PDHA1,SMARCB1,RND3,NDUFA12,TAPT1,RHOBTB1,TMEM39A,SSR2,RAB35,EED,STX5,EIF2S1,RAB1B,TCP1,RHOH,TMEM97,CCT7,LAMP2,RAB5C,PTDSS1,PPIB,FAM241A,DDRGK1,AGR2,PEX3,NDUFB8,DRG1 |
| 3.389e-14 | -31.02 | YAP1 (Yes1 associated transcriptional regulator) | protein interactions | 10413 | 1064 | 409 | 19454 | 5460 |
DNAJC10,SUB1,RPS17,BUB3,PPP1R10,NR1I2,ZBTB33,RPS3,CREB1,PSMC5,SDCBP,VPS4B,RPA2,ACACA,SUMO1,CAPN1,SPTBN1,GTF3C4,KDM1A,HSPA5,MARS1,THUMPD1,PRDX6,SNRNP70,AGPAT1,USP15,RPL10A,RPS2,CDK12,PGAM1,RPS16,TMPO,SYNCRIP,EEF1B2,NHERF1,IK,CHAMP1,TFCP2,PSMC3,TAF2,ZMYM4,RPAP2,RBCK1,KPNA2,TOLLIP,CAPZA1,SLC25A11,IDH1,SLC16A1,H1-10,LAMTOR1,PAPOLA,PSMD6,ATP5F1B,EFHD2,GTF2F2,PAK2,ADSS2,PIP4P2,RPL27A,GNB4,MT2A,XRCC5,EP300,ARRDC3,HSPA8,YWHAB,HSPB1,TCP1,TRAPPC10,CORO1C,SV2B,GNAZ,RPL18,CRKL,MTA2,CSTF2T,TRAF2,SOX2,KRAS,NFE2,CCT8,PABPC1,TRIM11,RUVBL2,RPAP3,CCDC22,AR,NONO,USP14,PPP1CC,TUFM,ATP5F1A,RUNX1,YES1,SLC25A4,RPL13A,TXN,LDHA,SMAD5,HOMER1,LURAP1,STUB1,PTEN,HSP90B1,TOX4,LMNA,JUP,RPLP0,RPS14,SAP30BP,SMC4,RPL4,PRRG1,GTF2I,CERS2,DNAJC7,GLO1,AIFM1,DMAP1,MRPL49,ILF2,TBK1,RPL15,SMAD1,EEF1A1,WASL,THRAP3,TOM1,MSH6,EIF3E,MDC1,RPS13,CTNND1,DLG1,PC,ZC3H11A,MYO6,LMNB1,TAFAZZIN,HNF1B,MCM3,OTUD7B,SPINDOC,RBBP4,DYNLL1,GNB1,RPL19,RAN,ADNP,MED23,MYL6,H1-5,PRDX3,PPP1CB,MCMBP,SKP1,UNC45A,TGFB1I1,COIL,WBP2,GNA14,HADHA,NUBP2,ATP5IF1,KDM2A,TRAF6,PSMD10,UBE2D1,RPL23,RSBN1L,RASSF8,CDIP1,SAV1,TAF7,PRDX1,EIF3D,SNX2,SNX1,SPTAN1,RPL7,WIF1,CACYBP,PHB1,WDR6,THOC2,IGBP1,TMEM59L,GTF2E2,TRIM37,H19,RBBP7,RPS24,CHRAC1,OAT,RPL7A,SMARCA5,AKT1,CFL1,MAP3K3,CDC20,UQCRC2,MACROH2A1,RNF187,GNAO1,PHAX,WWP1,TFIP11,MYCT1,CD2AP,PIP4P1,IRF3,PML,LIN7C,RPL27,DDX46,ARFIP1,DLAT,PGK1,RPL24,H2AC4,SMCHD1,MED27,MAP4,TSNAX,GAPDH,MIF,CAND1,MYL12A,ADD1,GNAI3,RPSA,TP53,MVD,TMEM252,ESS2,HNRNPK,PSMA5,NEDD8,CTSC,RPL17,DHX9,FBXW11,CCT2,CKB,RPS26,PSMA4,HNRNPC,LDHB,SFN,MYC,CREBBP,SNRPB,BAG3,BTF3,STAT1,TAGLN2,MATR3,APEX1,ESR2,POLR2B,MIDEAS,VDAC2,SMU1,PRMT5,MAP2K1,NUFIP2,EIF4B,ZC3H14,GPC4,PHB2,EEF1G,SRSF2,RPS28,DDX39B,DDX5,GPHN,NCK1,CDC23,DDX1,RPL6,BAZ1B,LAMP2,CTNNB1,XPO1,YWHAG,YWHAH,SUMO3,RPS10,TTC9C,HSP90AB1,SWAP70,SIN3A,PLS3,TUBB4B,RPS23,SMARCB1,RPS7,EEF2,FOXJ3,TUBA1A,RUVBL1,PSMA2,HNRNPF,RPS4X,GNA11,RPL31,LDLRAD4,MYO1B,SMAD2,DNAJC8,TMOD3,PDCD5,GNAI2,SCML2,SLC25A31,UBE2L3,CTTN,TUBA1B,ENO1,CTNNA1,GAB1,ALB,HNRNPH3,RARS1,UBA52,SF3A1,FBXW7,PDHB,NF2,RTN4,CNN3,FAM133B,MOV10,ACTA2,SMAD3,RPL12,TES,NAA30,DHRS7B,CCT5,HUWE1,SFXN1,TCOF1,NKRF,PPP1R12A,RAB1A,IGF1R,RPL23A,CPNE2,YWHAZ,CCDC25,RPS5,HSP90AA1,SMARCE1,TAB1,SIAH1,ACTB,TUBB,MED17,LAMTOR3,PRDX2,PRRC2A,UBTD1,ENO2,VPS72,GNG12,RPS9,H2AC1,SLC25A3,MAPKAPK5,ACTL6A,RP2,UCHL3,RNF11,PDAP1,VCPIP1,HNRNPD,PDIA3,HNRNPA1,INA,DHX15,EGLN3,PPIA,PSMB5,PSMB4,RPL9,PPID,SKA3,RPN1,JPT2,CSNK1E,ARFGAP1,PPP2R1A,JUN,UFM1,AHCYL1,SSRP1,FLOT1,GTF3C3,HNRNPA2B1,SLC25A5,NEK9,HSPD1,ZYX,NUDT5,SRSF7,BAG2,PCNA |
| 3.626e-14 | -30.95 | primary metabolic process | biological process | GO:0044238 | 7206 | 2350 | 18204 | 5365 |
DDR1,KTI12,CFTR,DIS3L,MTRES1,LDB1,RPS16,AIPL1,STK38L,BOLA2B,SLC29A1,ACOT8,FBXO3,PSMD14,RPS28,TRIR,UFM1,RPF2,ATG3,SPHK2,PPAN,H2AX,RAG1,FBXW11,SPCS1,TRIM23,OGG1,QRSL1,KLK9,MME,RPS29,PSMD4,STX1A,RDH11,INO80C,MTMR12,MINDY3,EPHA2,PIR,S100A10,CAB39,RNF182,BATF,DPAGT1,PRPF4,MAPK10,BRIX1,ADIPOQ,APPBP2,PLAAT3,GALNT2,ROCK2,FBXO31,TRAF2,CINP,RPS3,EEF2,TMEM106B,SENP8,TRIM6,ETF1,PDE9A,DCP2,STK24,GNPDA1,KDSR,RNF20,BTG2,TSPO,RNF187,CYP7A1,NSDHL,LIPA,ACOX1,RPL23,TAMM41,CCNA2,CSNK1A1,NUDT7,GNPDA2,UBE2H,CLN8,RAD21,LSM6,POLR2L,CNOT7,GAPDH,PLPPR1,MYRF,PYCR1,CEP41,SLC25A11,FBXO22,RPS5,EDEM3,TPRA1,OSBPL8,MRPL47,PLAAT5,PCYOX1L,AK3,ITK,ATP5F1E,AASDHPPT,TTLL10,NDUFAB1,HELT,PTPRQ,ATXN1L,MTHFD2L,FGFR1,VASH1,GGTA1,PIWIL4,ACSS2,HUWE1,PTPN11,ENC1,CCL11,POLR1B,CTRB2,SEC11A,DHRS3,FKBP10,TRIM27,MRPS18A,TSEN54,NONO,CDK6,TFPT,FBXL7,UGDH,TAF7,PFDN1,GNPTG,HADHA,SPPL3,IDO1,ORC6,PEDS1,IL21,APEX2,ZMAT5,ACBD7,ZNF451,EEF1AKMT3,VPS72,VPS4A,FHIT,PRCP,GPX4,CWF19L1,BAZ1B,TECR,ATP1B1,HYCC2,CISD1,MRPL36,NDUFA2,CDK7,ETNK2,P4HA2,ERG28,EDEM1,USP14,PFDN2,HPS6,NABP1,MACROH2A1,CTBP1,PRKCB,WDR3,AHSA1,PAGR1,SNRPE,SNRPA1,PTPN22,NFKBIB,GAL3ST1,PDE8A,NDUFA1,TRIM37,USP13,PEX13,TTC4,NPM3,QNG1,FMO1,ABHD14B,EIF3J,PXYLP1,RP9,PIWIL2,AP5S1,FARSA,VPS4B,PDHB,RTCB,UBE2F,ADTRP,SNRPD3,KLHL12,RNF39,POLB,RBM7,SRPK2,PLSCR3,PAK6,METAP1,QPCTL,DTWD1,FCN2,ATP5F1B,SNAPC1,RING1,PCNA,CPT1B,TCEANC2,SHOC1,NUDT5,ZMPSTE24,ZCRB1,IFIH1,ABHD12,COPS4,TAF2,WWP1,POLR2I,YBEY,WBP11,SNRPA,EGR2,PPP1R2,RPS27L,ARB2A,PLPP6,TRIM26,ATP6V1A,PFDN6,TRIM11,ACHE,USP8,LDAH,CRAT,RC3H2,VCPKMT,SELENOO,DCTPP1,MRPS33,SMG5,FCF1,HSP90AB1,CBFB,CD28,PTPRZ1,LDHB,ERLIN1,FKBP1B,LYPLAL1,CAV3,SMPD2,OXCT1,KCTD17,MSRB1,MBLAC2,PELI3,MARCHF5,HTR2A,INPP5K,OST4,USP15,HSP90AA1,SOCS4,NDUFA12,POLR3GL,EIF2S2,DAD1,CDK5R1,WDR45,CYP2F1,SPON1,DNAJC30,KLHL7,FMO2,DNAJC19,WWP2,HNRNPA1,NUDT18,MRPL16,THOC2,GLO1,PMPCA,IER3,ANAPC4,CREB1,SELENOF,PTGES,TDRD7,PRDX3,SCNM1,G6PC3,APOBEC3G,HSPB2,SLU7,TTC1,GSTM4,THBD,NUDT12,NAE1,SELENOI,CCNF,CHKB,TRAF6,NLGN2,URAD,TXNL4A,SYCE3,TMEM59,RNF40,TRIB1,ACAT1,FOS,PRSS12,CHI3L1,PHKA1,PRSS37,CLPX,IRF2BPL,FBXW4,MRPL18,HINT2,HNRNPF,SLC25A44,CYP2C9,RPAP2,NFKB1,GLYATL3,RNASET2,ARG2,B3GNT2,MGAT4A,SUPT3H,PLP1,P3H1,LIPT2,PPAT,ZDHHC4,UBL4A,WDR83,NDUFA5,ELP3,DNAJC4,SNRNP27,AKR1B1,ATF3,TYW3,FNTB,GFUS,CMTR1,ATG16L1,DUSP22,GPAA1,TRMT1L,SMAD3,KMT5B,TEX19,EIF4A3,HNRNPD,SNRPN,TAF9,SELENOK,TRIM62,IRF2BP1,KRR1,UTP15,FAH,C1GALT1C1,PIGK,MAN1A2,TMEM208,PQBP1,STYK1,DNAJC5,IRF1,SLC30A5,ASNSD1,NTRK2,TFIP11,DDAH2,CCT5,PGK1,TLCD3B,RPS24,IFI16,FBXO44,NBN,METTL14,HS3ST3A1,AKR1C1,SNX17,ETFB,B4GALT4,AKR7A2,MECP2,UBL5,BMPR2,EXOSC3,CELF6,LYPLA1,EDC3,MRPL50,BNIP3L,SRGN,MTMR2,NRDE2,GXYLT2,EXT1,PTGES3,XPNPEP1,SUMO2,PPID,PSMB4,MSRB3,CDK20,SRC,PPIL3,ATP5MC3,CHPF2,AIG1,PLCB2,PSEN2,METTL6,ISCA2,SF3B6,IDH2,HNRNPK,TRIM21,POLR2F,NOVA1,ATF4,MGAT4B,MEIOB,RPL8,DTL,NUDT4,ZRANB2,TENT2,BIRC5,MACROD1,RBM27,RNF121,FAU,PRKRA,MRPL53,MEF2A,PGM1,USP30,DHX38,DLST,HTRA1,SIAE,ADRB3,PSMB3,SKP1,PLAA,CTDSP1,CDK12,WDSUB1,ATG4C,GYS1,CRKL,TRIM24,RIC3,MARCHF4,CDKL2,CHPF,TSPAN15,ADCY2,EIF3G,GSK3A,PPP1R8,SPTSSA,AKR1A1,PSMD7,KPNA6,B4GALT7,BAD,DERL1,CDC7,GMNN,UBE2V2,RNASEH2C,DPH3,GON7,AKAP17A,MRPS35,PRMT5,UBXN6,ISG20,SDHAF2,SELENOS,DDI1,MRPS34,UQCC3,RFC3,GEMIN8,RNF103,EP300,HSD17B10,NPC1L1,CSTF3,PIK3R3,RPN1,WDR77,CRYL1,NPR2,BACH1,CTSK,RPF1,CRTAP,GPX1,RNF208,TMEM106A,RWDD1,ESS2,MFN1,TIA1,GPX5,SLC35A2,PAFAH1B3,ENPEP,DPH5,RBFOX3,HADH,METTL2A,INHA,ECRG4,MRPL22,SIN3A,CHMP2A,SNAPC3,LYAR,APTX,PHYH,EIF4E3,MPHOSPH10,RPL26L1,SNAPIN,POLR3F,RMI2,RMND1,GANAB,RPLP0,OVGP1,PNP,MORC2,RNF122,HSPD1,MRPS7,LUC7L3,GNMT,ADGB,MRPL11,IMPA2,SULT1B1,WSB1,THUMPD1,OSGEPL1,SLC1A3,UPRT,ASMT,STOML2,UBE3A,DPP10,SNRPB2,RNF14,RNASE6,DUOXA2,POLR3B,UBE2E2,USP2,COPS7A,UBB,PDHA1,H2AB1,RP2,PPM1D,BOLA3,KCTD9,NLRP3,ABCF1,NHEJ1,FUT8,CASC3,RNF133,GGCX,CHST7,CSNK2B,LSM3,TOP1,MED4,SUPT5H,LCN1,LRAT,MPST,TAFAZZIN,RPL6,CASP4,RNF152,ILK,FDFT1,ZNF365,TNFAIP1,CD2BP2,GGT7,DNAJC10,STUB1,CYP4F12,CYP3A5,RPL28,CERK,CDK5,KLHL9,PLAC8,RSL24D1,PITPNA,PCLAF,RNF5,HECW1,KDM2A,GTF2A2,DUSP10,CCT8,CYP17A1,EXD2,MUL1,PPT1,GINS4,DUSP18,RDH12,TEX12,RPA2,ERLEC1,PHB1,MID1IP1,TRIM52,TRA2A,CAMKV,SLC25A12,ASB7,NAA35,DDX46,B4GALT3,CHMP4C,RBM3,TRMT61A,RBM15B,UFL1,PPP2R3A,WDR6,KPNA2,METAP2,LGALS3,DET1,CDC123,TRIM15,CYP27B1,CYP2C18,ZNF326,FAF1,PIWIL1,DROSHA,HEXB,FAR2,ZNF473,ZNHIT3,RPL9,PPIB,HSPA8,SCD5,PTPN1,INTS10,BAG2,CRBN,RBMX2,FBXO30,CLCA1,ST3GAL4,RARS1,MRPS11,USP39,ALKBH3,SORD,MDM2,FADS2,TRMT13,MPG,AGA,HENMT1,TP53,MAP1S,SPCS3,PSMB5,PYGM,SUMO3,RPL35,NCBP2,DDX5,GHRL,CSNK2A1,CPEB1,HNRNPA0,DHRS7B,PTPN5,AZIN1,CPSF4,PCMTD1,SOX9,NDFIP1,CBL,SART3,BAG3,PPIG,ERO1A,CWC15,IMP4,DCAF5,DNAJC25,MVD,RBM23,GLRX,LSM8,CYP1A1,MTRF1,QTRT2,CTTNBP2NL,FKBP1A,EIF4EBP2,XXYLT1,CTSB,PPTC7,NR1I2,DHX15,ANAPC11,PRPF19,DNPH1,ING5,PELO,CDC5L,OTULINL,DRG1,HSPA14,VIPAS39,SNRK,NUCKS1,CHRAC1,FKBP2,RFC2,DBR1,LDHA,RPP25L,OLA1,GLRX2,RNF8,STAT6,FAM8A1,THOC3,SF3A1,SRSF7,ZNHIT6,ADRB2,DDX4,CFAP20,PRDM4,MCM8,PRSS1,CHST9,GFM1,PLD3,TMUB2,DPEP1,KLHL15,ST6GALNAC3,DUSP3,FPGT,ZFAND2A,LRWD1,SUGP1,AANAT,SLC2A3,OTUD7B,RPRD1B,LORICRIN,LSM2,LTO1,GZMK,SMNDC1,PSMB10,NTMT1,CDC37L1,PAAF1,THAP1,MDC1,IL4,NDUFC2,GTF2H4,FAM98A,PDP2,ATP5PO,FXN,DGCR8,RPL37A,GPBP1L1,TRMO,CHID1,CYP3A43,CSNK1G3,RPL17,F9,CMA1,SWAP70,RNF7,NEU1,USP5,RUVBL2,YAE1,SLC25A17,LANCL2,MIF,NDUFS8,EIF5A2,PCSK2,REN,SHPRH,MAP3K12,UST,ACADSB,PDE7A,STK3,FBXO8,SETD7,RNF34,GDE1,SREK1IP1,RPS14,TRIM68,TLR3,DDX42,CDC16,HACD2,DYRK2,ALDH1L1,MTMR6,PPP2R5E,SECISBP2L,AGO1,CRYAB,SOCS2,FZR1,DMPK,C1D,APOBEC3A,USE1,TBCEL,PRPF31,RARRES2,G6PD,MRPS25,MYLIP,RPL7L1,PIAS1,TRMT10B,VPS54,DPP4,CDK4,ACOT13,TBK1,CYP21A2,XRCC5,GCFC2,DUSP6,PSMC5,GLRX5,CCL2,NPPC,RPL10A,PDE2A,RMND5B,KIN,RBM42,EIF5B,DNAJC1,NLRP1,MAK16,SYK,NPY1R,PCYT1B,HNRNPL,EAF2,S100A8,TESC,ZDHHC17,PRDX6,FBXW7,TRIM5,SELENOT,APOBEC3C,PPIC,UBAP1,APEH,VSIR,DCUN1D5,RBM17,CERS2,MED9,ABHD16B,TRIM32,TRMT112,GPAM,UBE2L3,PSMC4,CNOT6L,FA2H,MED23,KBTBD6,KLF1,AGK,VKORC1L1,ST3GAL5,PIK3R2,CDCA3,PRKACB,RNF148,YWHAZ,TERB2,CTNNBL1,BSCL2,AREL1,CAPN2,ELOVL4,HS2ST1,DEK,CAMK1,CDC40,PTDSS1,STT3A,NDUFB8,RPS11,UNC45A,NSMCE3,PPM1B,RRM1,NUDT16,EIF3E,CYP4V2,FGF23,CLK1,ALKBH2,VRK1,CTSA,GTF3C4,MGST3,METTL21A,SAMHD1,PPM1K,RB1CC1,LRP10,ADPRH,ASB11,ACO2,BACE1,RPL35A,UTP25,RNF41,UGT2A3,CD40LG,HSD17B8,PARP11,RBM41,PDE4B,ATP5PB,TAF10,PIK3CA,F7,ELOVL3,FBXL3,NMRK1,APEX1,MAP3K21,ZC4H2,CHST13,DPH6,GPIHBP1,SUPT4H1,GFM2,ROCK1,THOC1,RHBDL3,RPS10,ZFAND2B,CYP39A1,CDSN,DOLK,MND1,TERC,PFDN4,RPL13A,RPL27,EHHADH,XBP1,SPSB1,PAK2,CYTL1,TRIM63,IL2,GDPGP1,HIRA,PAIP2,SNAPC5,MRPL52,AR,RPL4,TAF11,PPP3R2,PIP5K1A,PCSK9,B4GALT1,USP46,PRKCE,PSMA3,GLCE,SRFBP1,B3GALT2,ATP5MC1,SMU1,PARL,DIO2,DCK,RGMA,CEBPE,SIAH2,BMP1,FUBP3,DUSP26,ACO1,HACD4,RPS4X,GPC1,LBR,FKRP,RPL26,PDRG1,CCT7,PPP1R11,FEM1C,CYB5R3,CLK4,PSMA4,PIP4P2,PSMD6,ASPA,SIRT7,FBXO9,BAK1,VDR,PRPS1,B4GAT1,HDAC3,UBA3,ATG7,MTAP,TKTL1,ZBTB16,AQP11,MDH1,DNAJB6,HM13,PREP,RIMKLB,MMP20,RAMAC,JKAMP,TNIK,PSMB2,B3GALNT1,UBE2S,PAX6,UQCRC2,URM1,GFPT1,WNT10B,CHMP2B,OTUD6B,PNPLA8,BABAM1,RPL7A,TUFM,PRKAG1,CASP12,TP53INP2,SLC35C1,NUS1,PPP2CB,PPP1R12A,ACTL6A,AKT3,FOXP3,RCL1,AGPAT5,RNF181,CLIP3,PAFAH1B2,GNPNAT1,RPL12,KLHL25,DUS4L,GPD2,TENT4A,THOC6,POP5,POLD4,IMMP2L,MAGEC2,MMP14,MCM6,ABHD4,UBE2K,UTP6,NDST1,EIF4E,PADI2,CHMP1A,DDX39B,CETN2,CDIPT,WDR83OS,RNF144B,MTHFS,MCMBP,GANC,PRKCA,LMAN1,ACVR1,RAD23B,AZIN2,EIF4E2,EDEM2,F2,AMT,PIP4K2C,POMT2,PPIH,HSD17B1,CAPN1,PLSCR1,DCUN1D1,TSEN34,FRA10AC1,UBE2E3,PGGT1B,EEF1B2,INPPL1,USP16,RABGGTB,APOBEC3B,HSP90B1,ELOVL6,RFC4,GUCY1B1,TRA2B,NFE2L1,STRADB,NUDT3,ECHDC1,TFB1M,CGAS,KCTD11,FEM1A,DFFA,PITPNB,ABHD17A,ZDHHC8,MBL2,HMGB1,RAB6A,H2BC1,KLK6,VPS28,GTPBP1,BCCIP,HNRNPH3,CARS1,ZC3H15,NAA15,MMP21,RBBP7,MAP3K11,DDRGK1,SRSF8,STN1,SRSF2,GID4,RAF1,MSX1,TRAF1,RFC5,PPP1R1B,PRKX,COP1,SDHC,SPCS2,GSTO2,UBR7,HECTD1,UFD1,FAXDC2,GOLGA7B,SLA2,HDHD5,PRKCQ,ADH1A,SESN2,PPARG,POLE4,ST8SIA4,DESI1,JOSD1,B4GALT6,PTGDS,EPO,NR4A2,MNAT1,CUL2,FANCG,MKKS,CHCHD4,PNPLA4,EGR1,IKBKB,NCSTN,EIF4H,YTHDF2,RPS20,EZH2,UPF3B,TBCE,COMT,PSENEN,CMTR2,PLPP4,SRSF1,CHMP1B,RRP7A,ADORA1,DCLRE1C,SMG9,EYA3,DDIT3,DNAJC2,POLE3,ENO2,CHST10,HSD17B11,CTSC,FKBP8,NOP9,LCMT1,SVBP,ERCC3,COX10,CYGB,UBE2D3,PGAP4,TRIM22,AIP,ATP5PF,MTF1,PLA2G12A,FEN1,MRPL9,CSTA,PTTG1,HSPE1,ADAMTS20,PYM1,ATP1A2,CCT2,PGPEP1,SMAD1,KGD4,ILVBL,XPO5,COIL,FOSL2,ORC5,RNF126,HNRNPC,METTL25B,OAS1,SETD3,IDH1,EEF2KMT,COPS5,SUMO1,PRSS23,GCLC,DYRK1A,GSTM2,PGAM1,EIF2D,KLK3,MARCHF3,MPDU1,RBP2,ZDHHC24,RPL22,PROX1,CREBBP,DCAF11,DPY30,STBD1,MRPL40,GTF2H5,ADAMTS10,PPP1R3C,TWNK,RPP21,DRG2,ACADS,ADAMTS1,FBXL4,CPT2,NUDT2,CYP2D6,IRF9,MPHOSPH6,RBM22,ALKBH5,BRCA1,BUD31,SMAD2,SNRNP70,IDE,APOBEC3F,MRPS23,SNRPG,UBE2I,MTM1,TNKS2,PSEN1,MRPS21,DTYMK,RNF113A,PRDX4,RBBP8,SOCS3,CAV1,CELA3B,COQ8B,PPP1CB,MEPCE,MTG1,NDST3,RBFOX2,TNKS,TAB1,NME4,CDKN2D,PIM2,ODC1,NAA60,RPP14,POLR3H,ACOT6,IDH3B,ST3GAL1,APOBEC3D,ISYNA1,CYP26A1,ATP6AP2,POLR2D,SSBP1,SNIP1,CDK1,RPS6KA4,OAT,MED21,NFIL3,UBE2A,PWP2,GLYAT,NAA50,CTDSP2,FITM2,TPH2,FAAP100,CASK,MRPS28,CYP4F8,PREPL,MRPS26,ACTMAP,TYW5,RPL23A,FBXO11,ZER1,SLC35A1,HSPB1,SLC25A1,TDP1,MARS1,DAPK1,FAF2,ZSWIM7,CDC20,DNAJC7,FAM20B,ZDHHC16,MRPL24,TPST1,TSR3,NEK2,CD2AP,CD38,NDP,FKTN,DNLZ,CSGALNACT2,NAA11,UBLCP1,GADD45A,UTP23,UMPS,DISC1,RPL32,UGP2,BMPR1B,TFCP2,NUDT9,CBR4,PML,SNRPD2,SPATA2,HS3ST1,TERT,GTF2E2,NDUFB5,FUT9,EIF2S1,RPL24,MRPL20,ALOX5AP,PABPC1,MRPL33,UBXN2B,CLU,ANAPC13,OTULIN,SDS,MED30,RPL3,RPL19,CISH,PKNOX1,RPS7,RNASEH1,HSD17B6,ADIPOR1,PSMA1,STK38,GRPEL1,SARM1,PCBD1,NT5C2,ATG4A,CRTC2,EIF1AX,PNRC1,POLD2,TEX264,ELOC,ALYREF,GTF2IRD1,PHKB,GSTO1,DTWD2,TRIM3,SNAPC2,CCDC3,RPP25,PGS1,EIF2B5,EIF1AD,MGAT1,EIF3K,FBXO7,GCNT3,NFE2L2,DNAJB4,AMY2B,AKR1C2,PRMT6,PTS,HACD1,NOB1,IVNS1ABP,SMARCB1,BMPR1A,SACM1L,GOLGA7,DRAP1,TMEM199,SLC38A1,SPSB3,UBASH3B,SMUG1,SRSF4,PDIA6,SLC25A21,NME1,CSTF2T,MMP28,KCNJ11,PDSS2,EIF1B,SMARCA5,PIWIL3,SERPINH1,DAG1,SDR42E1,MRPL51,CBLL1,TCOF1,POLR2G,SQSTM1,LEP,RAB40AL,SNRPB,MCM3,RNF146,GALNT1,MED17,PLCL1,SERINC3,ELOF1,STK16,TRIM45,TESK2,SENP5,METTL22,CPSF1,HPF1,RIOK2,SEC61B,MRPS18B,EIF2AK2,POLL,PSMC3,STK26,NUP153,UBE2M,DESI2,CYP2C8,UBE2N,RRN3,PTEN,JAK2,DTD2,APOC4,DDX39A,MED31,MORF4L1,FBXL19,INTS6L,USP3,CAND1,TSR2,GALNT17,VLDLR,ASF1A,CRY1,POLR1D,SMCHD1,ACACA,ABCE1,UGCG,UBE2G2,BRS3,UBE2V1,DCAF16,PYCR2,NOP53,RPS27A,PDIA2,MAPK4,LSM4,DNASE1L1,RNF128,INO80E,SMAD4,ASB3,MAGOH,TTL,RPSA,SNX5,DR1,CERS6,POP7,ARMC8,KARS1,GK5,EIF3D,PSMD12,NAA16,PRKD3,IAH1,SHLD1,HYAL2,CYP2R1,CTNNB1,CYFIP2,NTAQ1,KLK5,COPS7B,TSNAX,GPT,SMURF1,PCK2,OGDHL,HACD3,UBE2B,JAK1,GUK1,RHOBTB3,CREBL2,PRPSAP1,MAEA,NGDN,SYNCRIP,ELP6,WDR82,ANAPC2,PHKG1,KLHL24,DHRS4,CPNE1,ECD,EEF1G,RPS2,ETFA,ADCY3,MED29,KHDC4,RPS23,IFI27,HSPA13,PC,ELOVL7,DCAKD,MLH3,ENTPD3,NEURL2,CD36,BAP1,PMAIP1,RPLP1,NDUFS3,IREB2,DXO,LIG3,SRSF10,HYPK,HAS3,TRIM34,TOP3B,DMAP1,AURKAIP1,ENO1,LDLR,EEF1A1,NEUROD2,LANCL1,GAL3ST4,PPP4C,TRAF7,RPL39,UCK2,PAK5,PELI1,ST13,PPARA,NIM1K,THRAP3,BRAP,RNASEL,IDH3A,FGR,RPS17,GTF2F1,ABHD6,CSK,ERP29,STAMBP,NDUFB6,KBTBD13,PI3,CRMP1,VIRMA,GALNT12,CHST2,RBM38,SNRPD1,CEBPG,GTF3C3,CNDP2,MFAP1,ALDH1A3,SDHB,MAPKAPK3,OTUD6A,PYGB,CTSD,NFYA,DCTD,SDR16C5,CDK9,RBM5,PRPF18,IK,ELOVL1,PTPMT1,RB1,RNF141,RSRC1,TYMS,CYP11B1,SSU72,DDAH1,ORMDL3,TOP2B,NSFL1C,TOPBP1,BCKDK,BCL6,SH3BGRL,PFDN5,ITGB8,HINFP,ABHD5,MRPL34,FBP1,FITM1,ATP5MK,EPHB6,MED11,CSKMT,PSMD3,PLG,TNF,GALC,SHMT1,GRPEL2,CYP11B2,HMGA1,SF3B1,TMUB1,CDK8,DIO1,PDIA3,RUVBL1,PDE12,PSMA2,CDO1,SNRNP40,NQO1,PPWD1,BPNT2,ALG2,KLHL22,TNFAIP8L3,MRPL10,CHMP5,PCMTD2,SUV39H1,GSTA1,PPP2R1A,MLF1,SLC16A1,SGTA,APOBEC3H,SC5D,GMPPB,AOX1,F10,PAPSS2,RPL15,ZNF668,HMCES,HINT1,RNF139,APOC2,SIAH1,PTPN4,TRIM44,RBCK1,B2M,PSMB9,RPS26,GPHN,CYB5R1,GABARAPL1,TCEA2,GTF2I,EIF2B2,ATAT1,PRIM2,EMG1,UGT1A1,MGMT,CRABP2,TMEM38B,TRIP4,RAD1,SAP18,CHORDC1,GEMIN7,CNOT8,LARGE1,INPP4A,PIP4P1,TOR1B,IP6K1,KLF4,B3GALT1,SPTSSB,TLR4,MPP1,RPS15,IMP3,TMEM165,POLR1H,TSSK1B,ACCS,CDC26,PIGC,DDX23,ST6GAL1,MAEL,VCPIP1,STK4,GNAI3,CIAO1,MAP3K3,NDUFV2,PPP1R1A,FBXL14,EPOP,CSGALNACT1,ANAPC16,MCM4,ZC3H7A,FTSJ1,CNP,ASCC1,PTAR1,LEPR,NEK7,SUB1,TMT1A,RPL7,RGN,EXOSC4,IL1R2,NSA2,HCST,MRPS17,ALG11,PDF,OLR1,DICER1,PSMB1,POLA2,TNNI3K,BECN1,TOPORS,ZCCHC7,GXYLT1,UBXN10,SF3B5,CNOT6,CHST11,DLG1,DNAJB9,BANF1,TLR7,ZBED1,RIMKLA,BUD23,TSN,NHP2,KDM1A,OS9,GAD2,MAP2K1,PPP1CC,PRMT2,HGS,CCS,CTU1,GDPD3,COL3A1,PGM2L1,MSL2,RMI1,FEM1B,PLA2G15,SPP1,FAM20C,HSD11B1,AMACR,SEPHS1,RPA3,SDF2L1,DHX9,ISG15,GINS3,GALNT4,UAP1,CCR6,ZNF345,MARCHF9,RNF167,SULT1A3,RPIA,PDE1A,TPSG1,UCHL3,ATP5MG,OSBP,GTF2B,NEDD8,RLIM,DHRS7,RNF11,TRMT5,ZMAT2,PGAP2,TRIM8,HYCC1,LIAS,RPL29,EIF2B3,SPOP,SOCS5,HSPA5,HTRA2,KLHL3,TRIM54,TAF5L,MRPL57,IGFBP3,RPL10L,LSM10,EPHX1,NUDT1,CYP4F22,GALE,ALG5,FASTKD5,THG1L,EEF1E1,RPL18,SNRNP48,FURIN,AK2,MYORG,MRPS16,RPS9,PLCXD3,STAMBPL1,FBXO25,ANAPC15,ATP5F1A,YWHAH,HERC3,SLC6A7,PMM2,BARX2,NDUFB7,TSSC4,ETFBKMT,GTF2F2,IL6ST,SRSF12,OSGEP,TUSC3,ZDHHC15,PELP1,MMUT,EPHA4,GBE1,ARMC7,RTRAF,IGF1R,RCHY1,IFT172,CSNK1E,FBXO32,PGAP3,AUH,PPIA,ABHD10,PLA2G4B,GTDC1,MRPL13,CCNH,DUSP9,MRPS9,PPM1M,MRPL12,SGMS2,DPEP3,ST8SIA5,CYP1B1,FKBP4,ENTPD4,TLR2,RPS13,AKAP8L,PICK1,RNF10,CSNK1A1L,PTHLH,YIPF5,PPIF,RNF26,BPGM,TRMT6,MECR,H2AC25,MRTO4,MGAT5B,DHRS11,WBP2,HPGDS,MAPKAPK5,UCK1,POLR2B,CACNB4,RDH10,CHRM3,PIGA,PIH1D1,EXTL2,DCUN1D3,ATP5F1D,HSD17B3,PPME1,GK2,BFAR,PSMC1,CH25H,NOC4L,ARFGEF1,SCG5,MSMO1,MED10,ACVR1B,DERL2,INTS12,NOL7,DPM2,SGF29,MRPL17,HDAC6,FOXA3,POLDIP2,NME2,LAP3,MED22,CCAR2,STK11,TMCC2,ALKBH4,LHB,SLC2A1,MCAT,ERH,PRSS8,WEE2,PARP2,UCKL1,KCTD10,TCEA1,RLIG1,GLUL,MRPS18C,YES1,DUSP1,SLC23A2,BIRC2,LACRT,MRM2,STAR,EGLN3,NPC2,PRKAB1,ASB1,SETD4,CUL3,SSRP1,CDK17,CCDC47,ZNRF1,PIK3R1,TRIM10,RAN,CPSF2,PGA4,NDUFS6,PSMD1,NIBAN2,PIGY,AK5,SLC52A3,TCP1,ASB8,TRUB1,MRPL49,CRYM,NDUFB4,IL15,GTF2E1,ABHD2,RPS12,HSPB6,FABP5,GTPBP2,BCL9,RCE1,MRPL41,PPM1G,HMGCS1,RPL31,CCAR1,CMPK1,PRRT1,RNF115,NDUFB10,CHST1,GTF2H2,TOR2A,WRAP53,G2E3,TRIM35,NT5C3A,GIN1,ANKIB1,TRMT11,ADH1B,COX11,RETSAT,ABCG2,INSIG2,VAC14,HNRNPA2B1,PIK3CG,WDR12,SPOPL,PAFAH1B1,FIG4,RBMS2,CDC23,GMPS,NDUFS2,ADK,OARD1,LYPLA2,CACUL1,WDR55,DBT,GNPAT,MAGOHB,DECR2,ADRM1,CAMP,SERINC1,COQ8A,EIF4A2,CPE,TOLLIP,TSPAN5,KIT,TP53I3,MSH6,TGFBR2,UBE2D1,RPE,HNRNPAB,PPP5C,TSG101,E4F1,MATCAP1,FTSJ3,PLA2G5,NR1H2,FN3KRP,EGLN2,ACER3,SCPEP1,DOHH,PAXX,CDK5RAP3,SLC25A10,SPRR1B,SYVN1,RPRD1A,CLP1,HERC4,PPP3CA,KBTBD2,ELAVL4,AKT1,DYRK1B,EXOSC8,UBA52,PCCB,MTERF2,METTL15,RTF2,ADAM21,EIF4B,PFKFB2,DNAJC24,ENY2,UBE2W,CNOT2,WTAP,MRPL23,UCP2,SGMS1,IGF1,APH1A,DKC1,NSG1,CALR,SKIC8,PSMA5,TTR,CHCHD1,GRSF1,GID8,GSTP1,TNFAIP3,RBBP4,NUDCD3,ATP5PD,INPP5E,ADM2,PLCB1,ORMDL1,METTL18,RPL10,MGST2,SMG8,PSMB11,PPP2R5A,OCRL,DHX16,DTD1,ST3GAL2,DNAJC3,B3GALT4,LPCAT3,DNAJB2,RBM34,SRD5A3,CDC73,REXO2,PSMB6,PAPOLA,DHRS4L1,MAD2L2,GMDS,ADSS2,RPL27A,NMI,MGME1,PIGW,EXOSC1,TAPBP,DUSP21,NUDT19,ASRGL1,VPS18,ACP6,NCAPG2,GTF2A1,MED27,COPS2,PSMA6,HS3ST5,AKT2,GGPS1,RPLP2,HECTD3,ERRFI1,DHPS,FUT1,SLC37A4,UHMK1,DLAT,SF3B4,OXSR1,SMN1,DAPK3,SLX1A,CYP27A1,NKX3-2,ACVR1C,DCAF4,ACSL4,FBP2,SLC2A8,RAB23,DNTT,ZDHHC14,DDX1,ERLIN2,POLR2C,SUCLG2,AGPAT1,LAMP2,TOM1L1,ENPP4,USP38,GP9,HEXA,BAX,TRAF3IP2,PSMB7,SEPHS2,ADAT1,ADIPOR2,DEGS1,NOP58,MMP9,ACAA2,LSM5,PAIP1 |
| 3.728e-14 | -30.92 | PSMA3 (proteasome 20S subunit alpha 3) | protein interactions | 5684 | 424 | 191 | 19454 | 5460 |
PSMC5,PSMA6,SRPK2,ADRM1,GORASP2,PSMB2,PTTG1,UBE2H,PGK1,HNRNPH2,EXOSC4,DLAT,BAP1,PML,HSPA5,PAAF1,CFTR,UBE2M,HEXIM1,ACACA,RPA2,CDK6,EEF1B2,GTF2B,CD274,STX6,RBM42,FZR1,CSNK2A1,GAPDH,KARS1,PGAM1,PSMG2,MAP1B,PSME1,STX11,PSMB10,MEPCE,FKBP8,PSMA5,NEDD8,HNRNPK,TGFBR2,RPSA,TP53,PSMC3,CCDC69,LMBR1L,IREB2,PSMB6,ESR2,PSMD4,ATP5F1B,PSMD6,MBL2,PSMD1,SNRPB,CPSF2,BAG3,MYC,HNRNPC,PSMA4,POMP,CKB,CCT2,PSMD14,HSPA8,DDX5,RAMAC,MIA2,XRCC5,FOS,DDI1,UFL1,PHB2,EEF1G,PRR13,PSMB3,OSR2,PSME2,CCT7,HSP90AB1,HNRNPL,DDX1,HSPB1,AGR2,PDIA6,CCT8,RERE,KRAS,PSMA1,PSMA2,HNRNPF,RUVBL1,VDAC1,ISG15,SERPINA3,EEF2,DHX38,MOB3C,TUBB4B,GANAB,ALB,STUB1,CCNF,TUBA1B,ENO1,VIRMA,LDHA,FBXO7,ATP5F1A,TUSC1,NONO,CCL28,USP14,XPOT,SYVN1,RPA3,FBXW7,ATG16L1,RBFOX2,PSMC4,SH3GLB2,HNRNPH3,METTL14,SNAI2,HSP90B1,GRM2,PRR3,PSMB1,MDM2,CRB3,PRNP,CALR,ZNF688,BTN2A2,PSMD7,EGR1,VTA1,HUWE1,TF,PSMB9,EEF1A1,CCT5,RAD23B,CLIC4,USP5,PRRC2A,ACTB,TENT5C,MCM3,HSP90AA1,RIT1,TBC1D16,FAM83A,PSMA3,PSMC1,SKP1,CYFIP2,KRTAP8-1,CDKN1A,PSMB7,CRYAB,PSMB5,PHB1,PSMB4,NUP35,HNRNPA1,PRPF19,PSMD3,STOML2,STX1A,ELP6,HBA1,PSMD10,APLN,UBE3A,HSPD1,HNRNPA2B1,RPS27A,MCM6,PSMD12,ANP32B,LASP1,RBBP7,ACTN4,ASPM,B3GNT2,ANP32A,RAF1,SART3 |
| 3.771e-14 | -30.91 | ECT2 (epithelial cell transforming 2) | protein interactions | 1894 | 871 | 345 | 19454 | 5460 |
USP6NL,NUFIP2,CSNK1A1,RPS28,SPECC1L,SF3B1,DDX5,SRSF2,FXR2,TRA2B,EEF1G,PHB2,PACSIN3,APOBEC3B,MYC,LDHB,HNRNPC,PSMD1,RALGAPA2,CPSF2,OR4N4,H1-1,PAPSS2,VDAC2,MATR3,RPL10,H1-3,TUBA1A,NUP37,RPS7,PLS3,H2BC1,RPS23,LIMD2,GNA11,RPL31,ABCF1,MYO1B,CDK5,HNRNPF,RUVBL1,RPS4X,DDX50,RPL6,RAB5C,TSPAN10,YWHAH,CTNNB1,PABPC1L,RPS10,HNRNPL,SNRPD3,HSP90AB1,CDC42,CYC1,LUC7L3,RBM23,RPL27,DDX46,PML,GAL3ST4,GFM1,RPS15,TRIM32,SMARCA5,RPL7A,ARHGAP21,CFL2,CFL1,IGF2BP1,ABCG2,OAT,TMA7,GNAO1,MACROH2A1,RPGRIP1L,TP53,RPSA,CAPZA2,CAPN2,GNAI3,DHX9,HNRNPK,RPL17,ROGDI,ELOC,TPM3,RPL24,AKAP8L,RPL32,ALYREF,CAND1,RPS27L,MYL12A,GKAP1,LARP4B,MFAP1,EMG1,RPS29,RHOB,YWHAZ,CNIH4,RPS5,ILK,GNG12,RPS9,EIF4A2,ERH,RPL29,ACTN4,ERLIN2,RPN1,SKA3,RPS11,HSPD1,HNRNPA2B1,MAEA,BAG2,SRSF7,S100A10,FLOT1,SSRP1,AHCYL1,HMGA1,HNRNPA1,HNRNPD,PDAP1,RPL8,RPL9,MRTO4,BRD9,RPLP2,INA,EGLN3,DHX15,PICALM,RPL26L1,PPM1G,PDHB,BRIX1,RPL26,RACGAP1,CTTN,TRIM27,NEGR1,RPS12,TMOD3,COPE,UBB,GNAI2,ACCS,LLPH,ACTR2,PPP1R12A,TCOF1,RPL23A,NOC4L,SMN1,MOV10,POR,RPL12,PTPN1,RPL35A,PABPC5,DIO3,CD59,CTBP1,RFC4,XRCC5,HNRNPA0,MT2A,GNB4,POMP,TFDP2,H1-10,FAM83B,BST2,PSMD4,SNRNP40,DES,PPIL3,PNMA2,RPL18,PABPC1,TOP2B,ACTR1B,H1-6,VDAC1,RPL28,PPIB,HSPB1,YWHAB,GNB3,SRSF1,CORO1C,RFX5,LYAR,DYNC1I2,SPTBN1,CAPN1,CSNK1A1L,H2BC11,SAMM50,UTP15,PARD6A,CORO6,BANF1,HNRNPH2,KDM1A,RPF2,GSTK1,RPS17,DNAJC10,RPS3,PSMA6,RPL10L,SUCLG2,SRPK2,MTCH2,RPAP2,ARPC3,NEFL,TNNI3K,TAF2,EIF1AD,PALM2AKAP2,SLC25A11,RPL3,KPNA2,CAPZA1,RBM17,TMA16,KCNJ10,SNRNP70,RPS2,RPL10A,TMOD2,SYNCRIP,RPS16,DKC1,ILVBL,TMPO,CDC5L,H1-5,MTX2,PPP1CB,AGGF1,MYL6,HADHA,COIL,G3BP2,FTL,SKP1,CFAP20,RFC5,PELO,AP2M1,RPL35,DYNLL1,RBBP4,CHCHD3,RPL19,GNB1,ASPM,CTSA,CHST10,ARGLU1,RPS24,SRSF8,FHL3,G3BP1,ETFA,MCM6,RFC3,RFC2,PRDX1,PRPF19,STOML2,RHOG,DDX23,AHSA1,RPL23,PPP3CA,WDR6,FOLR1,PHB1,RPLP1,LCA5L,NOP58,RPL7,SPTAN1,KCTD10,CACYBP,SERINC3,NPC2,CPSF4,RPS14,MYL12B,FAXC,JUP,CDK1,LMNA,HSP90B1,RPLP0,MACROH2A2,MME,CSTB,SQSTM1,ARPC2,GTF2I,EIF5B,RPL4,AATF,SEC13,ATP5F1A,PPP1CC,TUFM,DCAF16,XPOT,PELP1,RPS20,LDHA,RPL13A,TECR,RPL22,CCDC47,RPL15,ILF2,SLC25A10,HSD17B10,LSM4,THRAP3,ARF4,RPS13,PRDX4,MDC1,GALNT2,RNF14,AIFM1,H2AZ1,PWP2,PPP1R18,ARF6,TOP1,CAV1 |
| 4.031e-14 | -30.84 | RAB5C (RAB5C, member RAS oncogene family) | protein interactions | 5878 | 580 | 246 | 19454 | 5460 |
RAP1A,SNAP29,PREB,UBIAD1,TMEM165,TFRC,SURF4,SPRY1,FURIN,YIF1A,SLC16A1,TOLLIP,RAB3B,FKBP8,SLC6A8,ADIPOR2,DHRS7,SMIM12,NOS1AP,AGPAT1,CAMLG,COQ8A,ITGA6,RAC2,RAP1B,SLC39A10,VTI1B,ARL6IP5,DNAJC1,CAND1,SPPL3,LMAN1,STX6,SLC38A2,TMPO,SPTBN1,CFTR,CDC42,SSR1,RPA2,LDHAL6B,LEMD3,CSNK1G3,TEX264,BAP1,ARFIP1,RAB2A,SUGP1,GORASP2,SLC6A6,ARL6IP6,UBE2H,IGF2BP1,ATP1A1,NECTIN2,CDIPT,UQCRC2,STX10,B4GALT1,STBD1,PDHA1,TMEM87A,EFNB1,SLC20A2,VDAC1,USP30,RAB8B,VAMP8,DDRGK1,SLC38A9,PPFIBP1,AGR2,CBL,DUSP6,STX5,RHOH,RAB1B,CHMP2A,VAMP7,BET1,TOMM22,YIPF5,MAP2K1,CTBP1,JAGN1,RAB5A,AKAP1,EP300,STAU1,RER1,PHB2,GOSR1,LDHB,OST4,COX6B1,MYC,SLC30A5,LAMTOR1,ZMPSTE24,SLC38A1,OSGEP,DLST,VDAC2,FAM83B,TAX1BP1,ESR2,ATP6AP2,CCDC47,MAP1LC3B,LBR,SLC29A1,TRAPPC13,DLG1,STX8,RAB1A,NSDHL,SNAP23,SHISA2,SEPTIN7,HAPSTR1,CTNND1,SFT2D2,MOV10,EI24,RELL1,TMEM199,RAB23,HM13,RAB22A,ESYT1,SLC2A1,OSBPL8,PTPN1,HRAS,SRPRA,CDCA3,CGAS,ARF6,ALCAM,CAV1,UBA52,FUT8,ARHGAP1,SEC22B,RABL3,SLC35E1,GOLGA5,SLC12A2,CHMP1A,FADS2,RPA3,SPCS2,SQSTM1,MAVS,FLCN,YKT6,SLC7A1,TMEM209,SS18,CHMP2B,HMOX2,DEPDC1B,EPHA2,CDC73,NRP1,SCAMP2,VAMP3,CCNF,PTEN,YES1,SNX3,RHOJ,LDHA,RAB14,VKORC1L1,FERMT2,MARCKSL1,RAF1,TPD52,MACO1,TULP3,DSTYK,FAF2,YIPF3,GDI2,CHMP4C,STIM1,EZH2,VAMP2,RPN1,CYB5B,POLR2C,STX12,SCD5,SLC39A7,ETFA,SEMA4C,ARL5B,FLOT1,RETREG1,GCA,STOML2,WDR11,KDM2A,RASSF8,PHB1,WDR6,ATP6V1A,COPS2,GJA1,SNX2,OCRL,RAB11B,PPIA,PGRMC1,NOTCH2,TOR1AIP2,GINM1,DUSP22,RAB6A,VAPB,TBC1D17,EXD2,IMPACT,DUSP9,ATP2C1,PMAIP1,RABAC1,STX7,RAB11A,VEZT,NDUFB7,LMNB1,RHOB,BRCA1,ZCRB1,VMP1,SCFD1,CYB5R3,ARF1,FAM91A1,GPR89A,SEC61B,RMDN3,LAMTOR3,CHCHD3 |
| 4.078e-14 | -30.83 | SRP9 (signal recognition particle 9) | protein interactions | 6726 | 416 | 188 | 19454 | 5460 |
RPL10,IRF2,H1-10,FTSJ3,RPS26,CDKL2,MYC,COPS7A,RPL39,BTF3,SSR3,STAU1,EEF1G,RFC4,RPS28,P4HA2,SF3B1,PALS2,NUFIP2,EIF4B,RPL27A,GPC4,RPS10,FAM98A,NOB1,EIF2S1,SNRPA1,LYAR,RHOH,TRMT61A,RPRD1A,POU5F1,MGMT,RPL6,DDRGK1,CTNNB1,KRAS,RPL28,RPS4X,RPL31,TOP2B,PABPC1,SEC61G,RND3,MOB3C,AAMP,RPL18,RHOBTB1,TOP3B,RPS7,SMURF1,RPS3,SF3B6,EIF2S2,SRP54,SEC61A1,EIF3G,ANAPC4,MARCHF3,PDCD4,EXOSC1,IGF2BP1,UBE2H,RPL7A,RPS15,MARS1,BAP1,RPL27,LIN7C,EXOSC4,RPA2,SCLT1,UTP15,HEXIM1,CDC42,FZR1,RPS16,RPS27L,DKC1,CD274,RAC2,SNRNP70,RPL24,RPS2,RPL10A,DPP4,SRPRB,MEPCE,RPL17,METTL18,ABCE1,RPL3,DHX9,DDX42,RBM34,NUPR1,TP53,RPSA,EIF4A2,RPL35,PRRC2A,RPL19,FAU,TRMT6,EIF3K,SNRPD1,SNRPD2,RPL37A,RPS9,RHOB,RPS5,VMP1,RIT1,TOMM40,GPC1,MTHFD2L,HADHA,LARP4B,RND2,MPP1,RPL7,CEP19,TMEM237,RPL9,RPL8,RPLP2,HP1BP3,RPLP1,RHOG,RSBN1L,DICER1,EIF3D,TRIM26,UFM1,S100A10,ANP32B,PPAN,RPS24,EZH2,POLR2D,RPS11,POLR2C,SART3,RAF1,TXN,ZNF622,RHOJ,RPL13A,RPL22,PELP1,OPTN,EIF4A3,RPS20,ASCC1,CDC73,CASC3,CDC16,DHPS,RPL4,BRIX1,RHOU,PPM1G,PNO1,MTDH,TOX4,P3H1,GRM2,NOL7,RPL26L1,RPLP0,ATG16L1,EIF3J,SRPRA,SRP14,OSBPL8,RPS13,PTGES3,EIF3E,RIGI,SMN1,NKRF,DLG1,RPL23A,LLPH,ACTR2,ILF2,SRP72,RPL15 |
| 4.445e-14 | -30.74 | response to chemical | biological process | GO:0042221 | 3743 | 1291 | 18204 | 5365 |
AVPR1B,ATP1A1,RDH12,PDIA3,PDE12,EDA2R,ERLEC1,PHB1,ACTB,CYP11B2,VAPB,TNF,SHMT1,CX3CL1,TMUB1,XCL1,MUL1,TBC1D24,MIR98,FBP1,OR8G5,RNF5,DUSP10,IL1RAP,FGF7,TOP2B,STUB1,DNAJC10,CYP3A5,CYP4F12,HFE,CLDN4,CXCL12,RAB11B,CDK5,KCNMA1,CCL18,ILK,PTGER1,CASP4,GPR83,RAB31,MRGPRX1,RSRC1,TYMS,CYP11B1,SLC22A12,GREM2,OR52M1,SLC25A5,NUP35,LRRC8D,CITED1,RB1,FOLR1,TOP1,MIR105-1,DRGX,TMSB4X,LRAT,MPST,CDK9,CDKN1A,CLDN3,FOXC2,TAS2R16,TIFA,AIF1,PDCD1LG2,CSNK2B,MAPKAPK3,CXCR3,GJA1,CKLF,MIR214,MIR17,CCL25,NLRP3,CASTOR2,HPCA,SOST,DDX5,LEPR,NEK7,SOD2,CNP,POR,OR10A7,UBIAD1,BRINP1,MDM2,TNFSF10,HTR5A,OR8B8,GNAI3,ST6GAL1,TP53,ZBED3,HOMER1,OR5L1,KLF4,CLCA1,TOR1B,CYB5B,CER1,DLG4,TLR4,TRAM1,MSMP,ITGAV,GABBR1,ACKR3,UGT1A1,TIMP4,TRIP4,TMEM38B,PCGF2,GHR,LILRA3,TAS2R5,PTPN1,LARGE1,BRINP2,HSPA8,OR4M1,PPIB,FAF1,GPHN,CYP2C18,B2M,EIF2B2,SLC22A6,CBR3,RNF139,LGALS3,CYP27B1,TRIM44,SLC16A1,UFL1,CXCL13,SLC15A2,SCFD1,RPL15,AOX1,SGTA,ALG2,MLC1,KLHL22,PLGRKT,NQO1,HELLS,CDO1,CDKN1B,GSTA1,SUV39H1,CHMP5,RHOG,IRAK4,SLC25A12,GJB2,ADD1,DEFB1,SESN3,AANAT,RAB29,GABRG2,KCNMB1,EIF2B3,LIAS,IL18BP,JAGN1,ALB,TMUB2,DPEP1,ZFAND2A,MIR370,MAP2K3,KLHL15,SEMA5A,CCR6,CCR7,MAT2A,FAM8A1,ISG15,STAT6,SULT1A3,CST11,HAND2,MBD3,CXCL1,OSER1,SRSF7,HCFC2,ADRB2,ELMO2,RMI1,CXCR6,COL3A1,OR14J1,SDF2L1,DKK1,DHX9,SPP1,GLRX2,SYNGR1,KCNIP2,IRF8,CCS,GNA14,MAP2K1,MRC1,HDAC5,CCR1,REG1A,TAS2R40,OR4N4,IGFBP4,RASGRP2,SLC38A9,OR51E2,IL5,EIF4EBP2,TLR7,CPNE2,OS9,GAD2,KDM1A,NR1I2,CTSB,DHX15,BECN1,LRRC8C,HBB,CYP1A1,BRINP3,RAB13,DNAJB9,UBXN10,IGBP1,IL1R2,CPEB1,HNRNPA0,GHRL,ERO1A,CCR5,BAG3,OR4K13,CBL,STAT2,SOX9,FBXO32,CCL17,TIMP3,SLC6A2,PTGER2,IGF1R,SFRP1,PPIA,CDC42,SOCS2,NUPR1,CRYAB,RORB,KCNC1,CCL5,RGS19,KCNB1,IL2RB,DEFB124,AKAP12,EPHA4,TLR3,MIR200A,PELP1,IL6ST,CSF2,STX8,IRF3,OPRM1,SETD7,YWHAH,CCL3,HNF1B,ATP5F1A,MIF,IL12A,SCG2,BCL10,REN,LILRB1,CNTFR,SOD3,CMA1,GPR35,GSTA2,RUVBL2,STAMBPL1,GSTA4,EFNA5,EEF1E1,OR9I1,CLIC2,MAVS,CCL27,FXN,AQP3,MIR149,EPHX1,CCDC186,TXNRD2,NUDT1,CD81,MIR146A,HTRA2,IL20RB,SOCS5,HSPA5,OR5I1,MYD88,TACR1,IL4,UBE2L3,GPAM,TRIM32,RLIG1,ASIC1,GLUL,KBTBD6,LAMP3,EGLN3,YES1,CMTM7,DUSP1,SLC23A2,BIRC2,SLC2A1,LHB,OR5K1,OR1M1,MIR101-1,OR4K17,PRDX6,HDAC6,TAS2R7,PRR5L,S100A8,TESC,CREB3,STK11,SELENOT,HILPDA,CH25H,SYK,CCR4,NLRP1,DERL2,CD40,TMBIM6,OR4K1,ATP5F1D,PIGA,DRD1,CACNB4,CHRM3,MIR16-1,GPR75,OPRL1,NHERF1,IL2RA,RPL10A,NPPC,NGB,MAP2K6,CCL2,SYP,CHCHD2,DUSP6,PDE2A,WBP2,DPP4,VPS54,PICK1,VAMP3,P2RY11,XRCC5,CYRIB,TBK1,NPTX1,STAT5A,CDK4,PPIF,HBE1,OR7D4,RARRES2,G6PD,TLR2,CYP1B1,FKBP4,SLC12A2,P2RY12,PDCD4,ROCK1,STAU1,GPIHBP1,CAMP,MIR15A,SNN,GNPAT,MIR143,F7,IL17F,TIAM1,SLC13A5,PIK3CA,CD47,NDUFS2,ICAM1,TNNT2,NLGN1,ABCG2,MACO1,BACE1,CD58,PIK3CG,REG1B,SLC6A11,MIR140,PDE4B,FASLG,INSIG2,LAMTOR3,PRDX1,GPX7,IL18,CSH1,KLF3,TAS1R2,OR9K2,VEGFA,SLC38A2,LAMTOR2,TIMP1,MGST3,PDE1B,NSMCE3,TLR1,ABHD2,OR4A47,IL15,FGF23,MIR455,ALPL,OPRK1,FZD4,CAPN2,STIM1,RXFP2,MIR493,OR8B4,OR7E24,NR2E1,RAN,PIK3R1,CCDC47,PIK3R2,VKORC1L1,KLF1,CUL3,IPCEF1,OSM,CCL1,AMIGO1,TNFAIP3,GH1,TXNRD1,GSTP1,TXN,AGTRAP,BAK1,OR10Q1,VDR,MAP1B,CREB3L4,CXCL11,MT3,RETN,OXTR,ROMO1,IGF1,NFKBIA,UCP2,UBE2W,RFTN2,ABCB1,NSG1,CALR,IFNA13,ACO1,RTF2,TLR6,FKRP,PFKFB2,ITGA2,MIR182,ELAVL4,KBTBD2,CEBPE,WNT7A,PPP3CA,FAM107A,SLC6A1,OR4N5,AIFM1,AKT1,KCND2,IL1B,ESD,TGFB3,OR4E2,SYVN1,CDK5RAP3,PRKCE,EGLN2,KRT8,MIR448,ATF1,DIO2,PIP5K1A,PHC1,PPP5C,ACP5,USP46,NR1H2,CCL28,PCSK9,MIR187,NRP1,CCND1,IL2,MIRLET7B,TGFBR2,PAK2,TRIM63,AR,SOD1,CNR1,CYB5R4,SELENOV,XBP1,RPL13A,RPL27,EIF4A2,TOLLIP,MET,MIR320A,TERC,SLCO1B3,SLCO2B1,FAS,FLRT3,PID1,KIT,RTP4,TRAF3IP2,BAX,EIF4E,MIR379,TP53INP1,AHCYL1,CHRM4,IL6,GNAQ,IFNA10,PTP4A3,MMP9,CD86,ACAA2,PADI2,ADIPOR2,GNAO1,UQCRC1,OR5AP2,MIEF1,SLC2A8,GNRH1,DNTT,MIR223,ACVR1C,UBE2K,ERLIN2,DDX1,FCER1G,MMP14,OR51A4,PRNP,HAX1,OXSR1,OR13C8,TENT4A,CXCL14,DAPK3,OR2AT4,PPP1R12A,PPP2CB,VPS26B,AKT2,FOXP3,CD274,MPV17,CA2,MX1,ERRFI1,UCN,SRXN1,OPTN,GUCD1,HP,CDC42EP4,CD80,CIB2,TUFM,ADSS2,SMYD3,PAX6,RIGI,MIR204,OR5A2,CRYZ,EDNRA,WNT10B,TXNIP,OR8H3,HM13,SEMA4C,SELENON,TNIK,PSMB2,CDC73,DNAJB2,MIR96,JKAMP,IFNA2,DNAJC3,FABP4,TNFRSF1B,IFNK,PLCB1,OR2F1,TLR9,ATG7,LECT2,MGST2,KCNMB2,MCL1,MTAP,TRAF1,HRH3,DBH,PAQR8,TRAF2,CX3CR1,MIR145,PPP1R1B,RPS3,TRIM6,LY96,CCR3,ZC3H15,RBBP7,ADIPOQ,RAF1,SRSF2,OR2J3,PTGFR,H2AZ1,IL10,ROCK2,OR2H2,CXCR4,CAB39,OR5M9,HRAS,PYCARD,AGER,OR2W1,OR10A6,RHOB,HMGB1,GABRB3,OR2A25,GPX6,MME,EPHA2,RDH11,RGS2,CXCR1,PTK7,ASIC2,GUCY1B1,GPX3,TRA2B,ADO,OR4D11,ANKH,CGAS,OGG1,ADNP,TAS2R46,TNFRSF14,VAMP2,CXCL10,INPPL1,GLRA2,HSP90B1,SPHK2,CYC1,INA,CACYBP,SLC29A1,EDEM2,CCR2,PSMD14,PLSCR1,HSPB8,FBXO3,HSD17B1,PRKCA,OR5AN1,NEFL,CFTR,SCN2B,SLC22A8,RPS16,XAF1,RAD23B,ITGA6,CYGB,OR8B12,CLEC7A,GPR173,AZI2,MIR34A,OR4D2,IL13,ABCC5,RRAGA,CXCL8,LPAR1,TAF7,IDO1,CLIC4,CTSC,HADHA,CCL11,OR4N2,MICB,TOMM70,SELENOP,PTPN11,CCL8,AZGP1,CDK6,DDIT3,TSHR,P2RY1,FGFR1,COMT,RAC2,PRDX2,ADORA1,ESR2,EDEM3,PYCR1,NFYB,MIRLET7G,NCSTN,IL7,OR10G2,EZH2,IL3,CHRNB2,CHRNA7,MNAT1,NR4A2,SRP54,PTGDS,SLC6A4,TPBG,EPO,IKBKB,MYRF,IL34,GAPDH,EGR1,CHCHD4,OR2Y1,MKKS,LIPA,SP1,CYP7A1,JAML,EMX1,PPARG,PTGER4,CCNA2,CSNK1A1,SFRP4,RPL23,GAB1,UFD1,TSPO,BTG2,RAP2A,STK24,GSTO2,SESN2,JUP,SELENOW,GPNMB,PRKCQ,OR1S1,PGR,NAT2,TWNK,FGF10,PCNA,ATP5F1B,TF,NUDT2,RPP21,IL2RG,CRIP1,PLSCR3,SLC6A3,POLB,TGFB2,IL1A,VPS4B,CDH13,FOLR2,DDIT4,TNFSF18,MTDH,CCL20,ADTRP,GCLC,SELENOM,NFKBIB,PTPN22,FMO1,ATP6V1G1,GSTM2,PEX13,SLC25A24,LTA,FOSL2,MAP1LC3A,SHC1,CHGA,PRKCB,SUMO1,OAS1,RAP1B,IDH1,CRHR1,TWIST2,RNF126,OR8K1,SMAD1,CHRM1,MIR200C,ATP2B4,CRYGD,LCN8,IRF7,EDEM1,ACTN4,CAV2,OR6C4,LITAF,OR10G9,ATP1A2,HSPE1,OR2D3,GPX4,TADA3,CCL21,MIR20A,OR51M1,FZD3,CTNNA1,MTF1,AIP,MTARC2,LY6H,SELENOF,MYC,CREB1,MIR126,TUBA1B,TXNDC17,IFNAR1,GPR17,SEMA6C,DAPK1,HSPB2,FAF2,ZFAND6,MIR142,PRDX3,PTGES,HSPB1,MIR106B,FMO2,GSTM3,GLRA1,SOS2,HNRNPA1,CHRM5,SMAD5,HSP90AA1,NFIL3,CYP2F1,CDK5R1,GLYAT,CYP26A1,CD83,SRM,HTR2A,INPP5K,RPS6KA4,KLF9,CDK1,OR4K2,FKBP1B,ERLIN1,OR10G7,BLOC1S3,ZYX,CDKN2D,HSP90AB1,MEF2C,CAV3,OR6M1,MSTN,ACHE,CAV1,IFNB1,ATP6V1A,MCOLN1,PRDX4,SOCS3,GPBAR1,HTR1A,RBFOX2,USP8,ATP1A3,CLDN1,IDE,MIR324,HBEGF,PTN,DTYMK,CD4,LILRB4,OR4F6,GPR22,ARL6IP5,EGR2,PSEN1,IFIH1,RBM22,OR10A4,GABRB2,GFI1,SLPI,CYP2D6,SMAD2,MIR342,MIR421,TAF2,MIR31,SERPINB6,BRCA1,RHBDD3,TAF9,CRHBP,COL1A2,HNRNPD,WNT2,CCN3,CYBRD1,PLSCR4,RAP1A,EIF4A3,OR13A1,CLTRN,OR5V1,TFRC,PLP2,STC1,SARM1,SLC7A11,KCNJ10,SMAD3,NFKBIL1,AKR1B1,ATF3,NKX3-1,DNAJC4,OR4S2,FCGR2B,ADIPOR1,STAP1,CLU,TMIGD1,GNB1,RALB,WDR83,RPL3,CCL23,EIF2S1,B3GNT2,IL15RA,MT1M,KCNJ8,TERT,WBP1L,NFKB1,MRAS,CCL4L1,GNA11,ALOX5AP,GSTT1,CHI3L1,SLC11A2,FOS,HCLS1,OR4D9,PML,CYP2C9,RPAP2,PACRG,MT2A,GRM2,LRTM2,CUTA,SFTPD,CCL19,ACAT1,TRIB1,ADGRE2,UMPS,NINJ1,THBD,GSTM4,LAMTOR1,CD2AP,CD38,OR52W1,TRAF6,TLR10,NDP,TICAM2,HP1BP3,HBA1,OR5B3,MEF2A,PRKRA,TACR3,GPR37,IFNG,SNX10,RNF121,TAB2,PHB2,FIBIN,OR2A2,PLCB2,TFPI,SLC25A23,ATF4,TRIM21,EPS8,LEP,MGARP,KCNJ11,PTGES3,EXT1,CMBL,FAM162A,SST,ADRA1A,SH3BP4,SRC,CALY,DAG1,GNG2,ANGPT1,SERPINH1,SMARCA5,TMEM199,LILRA1,SEMA7A,BNIP3L,SLC41A1,SRSF4,AKR1C2,MT1A,AKR1C1,NFE2L2,TICAM1,DNAJB4,MECP2,TAS2R39,IFI16,FLRT2,PGK1,GSTK1,NTRK2,SHOC2,EIF2B5,ACTR2,FBXO44,IRF1,PQBP1,MAN1A2,GSTO1,SLC1A1,INMT,CYP2R1,CTNNB1,SLC1A2,HYAL2,CTSK,MIR95,NPR2,GPT,CCL24,GPX1,RALA,RNF103,EP300,RFC3,PDCD10,PIK3R3,OR4D6,DDI1,SMAD4,TANK,GRB10,SELENOS,MT1E,UBXN6,SEMA3C,DRD3,AMELX,OR4B1,LMNA,P2RY4,UBE2G2,NOP53,SERPIND1,TBC1D4,PYCR2,NDNF,HBM,L1CAM,AKR1A1,RAMP3,GSK3A,MIR545,ADCY2,CRY1,OR1F1,BAD,UGCG,DERL1,DEFB114,TUBA1A,ACACA,BCL2L1,STXBP1,JAK2,STAT1,BST2,LRP6,TIRAP,SS18,PLAA,STK26,OR10P1,MIR221,TRIM24,SLC8A1,CRKL,TXNRD3,CYP2C8,MSN,NCOA5,CDC42EP2,TMEM126B,CREBZF,GRIA1,CD14,EIF2AK2,SEC61B,GNAI2,OR4D5,IL22,CSK,SLITRK5,BGLAP,MIR107,CXCL9,MYO6,FOXP1,YWHAG,MIR185,MX2,UBE3A,IL12B,RNF14,LANCL1,MT1X,NEUROD2,IMPA2,GPX2,SULT1B1,OR10G3,FLOT1,RXRG,UPRT,IFNGR1,PELI1,PPARA,SLC1A3,GPR37L1,EMX2,VEGFC,PRL,JUNB,PNP,JUN,TAS2R13,LDLR,HSPD1,DMAP1,TRPC1,PMAIP1,MIR210,BAP1,CD36,RERG,SELL,OR51S1,OR8I2,KCNH1,LDOC1,ELK1,IFI27,ADCY3,OR6X1,SIN3A,AQP2,OR4Q3,SERPINB9,VAV2,RRAGB,LILRA2,CPNE1,AQP4,MSX2,GPX5,CD9,MIR21,HADH,CXCL3,SLCO1A2,PCK2,ABCC2,ILDR1,RGS10,GNRHR2,RWDD1,MYBL2,SYNCRIP,GUK1,RGCC,JAK1,UBE2B |
| 4.467e-14 | -30.74 | CUL7 (cullin 7) | protein interactions | 9820 | 836 | 333 | 19454 | 5460 |
RPS26,SERPINH1,GTPBP2,H1-1,CKB,CCT2,H2AZ2,H1-10,CHTOP,SNRPB,HNRNPAB,HNRNPC,CBX5,RPL10,ATP5F1B,PSMD4,MATR3,TAGLN2,SNRNP40,PSMD6,PRMT5,SF3B4,SMU1,MRPL13,APEX2,NCOA5,RALYL,RPL27A,ZC3H14,EMC1,HNRNPA0,EEF1G,STAU1,SF3B1,HDAC5,DDX5,DDX39B,SNRPA,XRCC5,DDX1,YWHAB,MAGOH,DRG1,FKBP4,PPIB,YWHAG,STK4,BAZ1B,DDX50,RPL6,RAB5C,HSP90AB1,ANKRA2,CCT7,TTC9C,RPS10,HNRNPL,TCP1,SNRPA1,SNRPD3,CORO1C,SPINT2,FUBP3,SRSF1,ZRANB2,CRKL,RPL18,TUBB4B,PNMA2,SOX2,TMEM59,KIF2A,ETFB,SUPT5H,RPS4X,TFG,POLDIP3,HNRNPDL,HNRNPF,RUVBL1,RUVBL2,MYO1B,EWSR1,PDIA6,RTCB,CCT8,TOP2B,PABPC1,IGF2BP1,ATP1A1,CFL1,RPF2,SMARCA5,RPL7A,CSTF3,RALA,MAP3K3,EIF4H,CSNK2B,SEC61A1,PSMC5,EIF2S2,MACROH2A1,SF3B6,RPS3,PSPC1,PAFAH1B3,GSTP1,UBE2M,TFB1M,HECTD1,LUC7L3,ZNF326,SUMO1,MARS1,HSPA5,WDR3,HNRNPH2,PGK1,SNX33,PRDX6,RAB9A,SEPTIN6,DDX46,APMAP,RPS2,RPL10A,SMCHD1,CHCHD1,SNRNP70,CSNK2A1,TPM3,GAPDH,COX5A,DKC1,TMPO,CDC5L,TMED9,MIF,MRPS9,SYNCRIP,EEF1B2,ALYREF,GPD2,DDX42,SURF4,CBX3,TFRC,IK,CAPZA2,ARPC3,ATP5PB,TP53,RPSA,KIF1C,CAPZA1,NEDD8,NUP107,PSMA5,KPNA2,HNRNPK,RPL3,MRPS18B,ERO1A,DHX9,MAP1B,MRPL52,RPS5,LMNB1,YWHAZ,CAV3,RBM15B,CUL3,GRB10,CHCHD3,RPL19,PRRC2A,USP5,RBBP4,RPL35,RPL7L1,SNRPD2,RPS9,ARF1,CPSF1,RAN,APOBEC3C,ATP5PO,USP39,ABCB1,IDH3B,PRDX3,PGRMC1,SKP1,AZGP1,HADHA,HNRNPD,RPL23,SLC20A1,DDX23,HBA1,HNRNPA1,PRDX1,HMGA1,UBXN6,PSMD3,PDIA3,PRPF19,STOML2,SRSF10,PPIA,ERLIN1,RAB11B,DHX15,LRWD1,NUP35,INA,NOP58,RPL7,HP1BP3,ATP6V1A,RPLP2,THOC2,RPL8,RPL9,PSMB4,PHB1,MYEF2,PLD3,SNRPE,ACTN4,GFPT1,PPP2R1A,RPL29,TULP3,ZNF263,SSRP1,FLOT1,DHX16,ETFA,HINT2,MKLN1,PCNA,BAG2,SRSF7,HSPD1,SLC25A5,HNRNPA2B1,ARGLU1,PPAN,STK11,ATP5F1A,TUFM,PPP1CC,RACGAP1,NONO,SEC13,TECR,DEK,LDHA,TMOD3,RAB14,RHOJ,YES1,GANAB,SYT2,ODR4,ACAT1,PELP1,CTNNA1,FBLN5,ENO1,EIF4A3,TUBA1B,RPL26L1,RPLP0,NOL7,HNRNPH3,MACROH2A2,CDK1,JUP,LMNA,HSP90B1,SLC12A2,RASGEF1C,SF3A1,RPS14,KCNH1,CCND1,SEC22B,MBD3,UTP23,BRIX1,NF2,EIF5B,FBXW7,PFKFB2,MTDH,SQSTM1,ARPC2,KLHL28,PRPF4,IDH3A,SIRT7,DNAJC7,EIF5A2,GLO1,CALR,TOP1,PWP2,SEC23A,PSMB1,RPL12,HACD3,RCHY1,EEF1AKMT3,ILF2,NDUFS3,ACTR2,LBR,EEF1A1,RPL15,CCT5,OLA1,RPS13,MDC1,MSH6,THRAP3,ZC3H11A,RPL23A,HSD17B10,RAB1A,TCOF1 |
| 4.557e-14 | -30.72 | PABPC1 (poly(A) binding protein cytoplasmic 1) | protein interactions | 26986 | 621 | 260 | 19454 | 5460 |
CASC3,MAPRE1,NAPA,PAIP2,CTSD,TUFM,PPP1CC,AR,ATP5F1A,RUNX1,FBXO7,RPL13A,NDN,TMOD3,VIRMA,SMAP2,METAP2,CCNF,GAB1,RPS20,GNPDA1,GSK3A,RARS1,RPLP0,TPT1,SF3A1,ATG16L1,RBMS2,RPL4,BRIX1,SIRT7,RPA3,SQSTM1,KIN,MOV10,CALR,ZMYND11,HDAC6,PRNP,DCUN1D1,CDK9,RCHY1,SMAD3,EFNA3,PRR3,UAP1,SRP72,ILF2,YTHDF2,CCT5,FBP1,RPL15,DDX39A,EEF1A1,APOBEC3D,CNOT7,FAF1,HSD17B10,ZC3H11A,BRCA1,CUL3,CUL2,ACO2,USP13,DYNLL1,RPL35,ACTB,EIF4A2,PRRC2A,RPL19,USP5,CNOT6,RAN,RPS9,RPL37A,EMC9,RNF7,LARP4B,ETF1,PRDX3,YTHDF1,G3BP2,MCRIP2,TERT,CRY1,HNRNPD,RB1CC1,PSMD3,TRA2A,HNRNPA1,RPL7,DHX15,CSF2,SRSF10,PHB1,IFIT2,RPLP2,IGBP1,TSG101,TYMS,CHMP4C,EZH2,RAF1,B3GNT2,ACTN4,TNF,G3BP1,SSRP1,TOB2,HNRNPA2B1,HSPD1,RC3H2,SPOP,UBE2H,IGF2BP1,ATP1A1,ELAVL2,RPL7A,MAT2A,ADRM1,SRPK2,SRC,CSTF3,PSPC1,RPS3,SGTA,HBB,RPA2,KLF4,HEXIM1,SUMO1,CFTR,MAEL,AGO1,H2AC13,MARS1,HSPA5,EIF4E,RPL27,BAP1,RNF113A,LSM12,TDRD7,SNRNP70,RPL10A,MAP4,KARS1,ENY2,API5,EDC3,GAPDH,CSNK2A1,COPS5,CD81,MIF,RPS16,CAND1,FZR1,RBM42,TMPO,ALYREF,SYNCRIP,PREP,NHERF1,DNAJC2,TFCP2,NUPR1,RNF8,TNRC6C,TP53,RPSA,UBL4A,KBTBD4,DUSP1,H2AX,HNRNPK,NEDD8,RPL17,MEPCE,PSME1,DHX9,RPL3,FBXW11,H1-10,ICAM1,PAPOLA,SFN,HNRNPAB,HNRNPC,PRMT6,MYC,BAG3,BTF3,RPL39,PSMD6,MATR3,RPL10,APEX1,DLST,CMTR1,PRMT5,PPT1,CNDP2,PIH1D1,EIF4B,NUFIP2,RPL27A,PABPC5,EEF1G,STAU1,UFL1,TRA2B,RPS28,DDX39B,SNRPA,AKAP1,EP300,DDX5,HSPA8,HDAC5,AGR2,HSPB1,DRG1,RPL6,WWP2,DCAF4L2,IFI16,GSTM3,CTNNB1,DDRGK1,CPEB1,XPO1,YWHAG,TCP1,DYNC1I2,SNRPD3,PAIP1,HNRNPL,PAPOLB,SRSF1,FUBP3,PDHA1,GLE1,PLS3,RPL18,MTA2,TOP3B,PAIP2B,EEF2,MSX2,ISG15,VDAC1,RUVBL1,HNRNPF,KRAS,HNRNPDL,RPS4X,PABPC1,CCT8,RTCB |
| 4.796e-14 | -30.67 | RPN2 (ribophorin II) | protein interactions | 6185 | 762 | 308 | 19454 | 5460 |
CYB5A,TYMS,PBDC1,PPP2CB,RAB11B,ATXN10,SPTAN1,WDR11,EIF3D,PTPN5,PDIA3,RB1CC1,C2CD2L,CDK5RAP3,RETREG1,AHCYL1,SAR1B,TRIM37,GNL1,EMC8,CYB5R1,PPP2R1A,FAF2,ACO1,MACO1,PLD3,CYB5B,RPN1,EZH2,STIM1,SEC61B,GPR89A,CYB5R3,ARF1,MAD2L2,ABHD12,MAD2L1,TAB1,RBBP4,UMPS,GGH,TOMM40,PDE4B,TM9SF4,CUL2,CUL3,PYCR1,VEZT,NIBAN2,KDSR,CBR3,VMP1,RIT1,BAX,NTRK3,SCFD1,LMNB1,PMAIP1,HACD1,G3BP2,ATAD1,CYFIP2,TOR1AIP2,PGRMC1,FABP7,FAM3C,FKBP10,VAPB,SEC23A,CDCA3,MYBL2,RCHY1,ALDH1A3,HACD3,SRPRA,PTPN1,ZBTB2,SLC25A12,CDK9,TOP1,DERL2,ALCAM,HM13,GMPPB,EMC4,TMEM199,EI24,OSBPL8,RAB3A,ESYT1,PSMD7,POR,SLC2A1,IGF1R,EMC2,HINT1,LIPA,PC,TMX3,CPNE2,EHD4,PPP1R12A,NSDHL,RAB1A,FAF1,GALNT2,PSEN1,MRPL22,SFT2D2,FBXO25,TUSC3,DNAJC30,HUWE1,LBR,MRPL11,CCDC47,TBK1,PDLIM4,PTEN,GLTP,DTYMK,CTNNA1,VAMP3,SEC63,GNAI2,VIRMA,VKORC1L1,UBB,SLC25A4,MAGOHB,MGST3,HMOX2,DNAJC8,DEPDC1B,ATP5F1A,ZNF687,CDC73,AP2A1,PEA15,ARFGAP3,SMPD2,RTN4,SPCS2,MTDH,FADS2,SIRT7,LRRC8D,PPM1G,RPA3,TMEM209,MRPL20,DAD1,FBXW7,CERS2,YKT6,EHD3,CDK7,SEC22B,ARHGAP1,RABL3,PSMC4,CARHSP1,RPLP0,METTL14,LSM2,SLC12A2,TMX4,PICALM,GRM2,HSP90B1,LMNA,STX5,EED,MAGED2,RAB1B,DDRGK1,FAM241A,PPFIBP1,PTDSS1,PFDN5,WWP2,TAX1BP3,AGR2,CRTAP,BPNT2,MYO1B,S100B,TOMM6,RPS4X,VDAC1,KRAS,ISG15,ETFB,STBD1,MOB3C,TAPT1,PDHA1,PTRH2,GGT7,SMU1,DLST,LMBR1L,VDAC2,PAPSS2,NCKAP1,ATP6AP2,ESR2,PCMTD1,STAT1,HMGCS1,OST4,MYC,TMEM38B,ZMPSTE24,FIS1,RPS26,PSMD14,H2AZ2,AKAP1,EP300,HDAC5,HSPA8,TMEM106B,DDX39B,LYG2,SAP18,ADRB2,STAU1,SSR3,UFL1,EMC1,EDEM3,SEC62,YIPF5,BET1,TOMM22,FDFT1,TRMT112,CAV2,UBAC2,RAC2,SLC39A10,CAMLG,COQ8A,STT3A,ACSL4,TMPO,LMAN1,ARL6IP5,DNAJC1,DHRS7,FAM20C,DPP4,AGPAT1,SMIM12,TMEM70,STX18,RAB13,ATP2B4,RUSF1,FKBP8,MEPCE,SLC6A8,SRPRB,KPNA2,H2AX,UBIAD1,TP53,PREB,UBL4A,FURIN,SLC25A24,TFCP2,SURF4,GPD2,PPP2R5E,SGTA,PITPNB,ATL1,UQCRC2,BCCIP,SMURF1,PLAGL1,ADRM1,CTSB,GORASP2,TIA1,GSTK1,SUB1,SLC25A1,RAB2A,OAT,ATP1A1,ARFIP1,RNF113A,TEX264,HSPA5,PAAF1,CDC42,PLP2,GABRA1,SPTBN1,LEMD3,HEXIM1,SSR1,USE1,RSAD2,RPA2 |
| 4.811e-14 | -30.67 | RPLP1 (ribosomal protein lateral stalk subunit P1) | protein interactions | 6176 | 297 | 144 | 19454 | 5460 |
RPS3,PSPC1,CDIPT,METAP2,PRKRA,RPS20,RPL13A,VIRMA,RPL7A,RPS17,USP14,PPP1CC,RC3H2,PDCD4,IGF2BP1,MAPRE1,UBE2H,RPL27,BAP1,SIRT7,PML,RNF113A,RPS15,FBXW7,RPL4,HSPA5,RPS14,ATG16L1,TPT1,CDC42,CFTR,RPA2,HEXIM1,RPLP0,SRP14,RPL12,RCHY1,LDLR,CD4,FZR1,CAND1,RPS16,PTP4A3,CDK9,RBM42,SURF6,MOV10,ENY2,EMC4,CSNK2A1,COPS5,HDAC6,SNRNP70,RPL24,RPS2,RPL10A,RPL23A,RAB27A,RPL3,NEDD8,CDK2AP2,RPS13,MEPCE,RIGI,RPL17,FBP1,UBL4A,TP53,RPSA,MAP1LC3B,EEF1A1,RPL15,DNAJC2,TMEM165,GEMIN7,SRP72,LMBR1L,IRF2,PELO,RPL37A,SEC61B,TAB1,LRIF1,RPL10,RPL19,ESR2,MYC,CUL2,GRB10,CUL3,ZNF668,BTF3,BRCA1,RPS5,RPS26,H1-1,DDX39B,SAT1,UBE2D3,PTN,UFL1,ADRB2,G3BP2,RPL27A,NUDT3,EMC9,PIH1D1,RPL9,PPP2CB,IFIT2,PHB1,IGBP1,RPLP2,RPLP1,RPS10,RPL7,MRPS35,WWP2,RPL6,NT5C2,DDRGK1,MAP3K14,RB1CC1,MGMT,DRG1,RPL23,DICER1,RPL31,RTCB,RPS24,KRAS,TNF,G3BP1,RPS27A,RPL28,PFDN1,RPS4X,RAF1,RPL29,RPS7,CHMP4C,RPS11,RPL18,RPS23 |
| 4.859e-14 | -30.66 | HSPA4 (heat shock protein family A (Hsp70) member 4) | protein interactions | 3308 | 630 | 263 | 19454 | 5460 |
MDM2,CGAS,PRNP,SEC23A,SMAD3,DNAJC7,HDAC6,MOV10,NFKB1,TLE1,OLA1,PRDX4,RIGI,CTNNBL1,HUWE1,HSPE1,VRK1,TRIM63,HAPSTR1,PC,TAGLN3,EMC2,FAF1,TLR4,GABPB1,MAP2K3,UBE2L3,SH3BGRL,VIRMA,TXN,PTEN,CTU1,MSN,CCNF,OPTN,STUB1,PELP1,TUBA1B,SMAD2,CDC73,TXNIP,TRAF3IP2,PPP1CC,AR,ZMYND19,CSK,PYCR2,NF2,SYVN1,MIS12,PRKCB,SQSTM1,MME,RPA3,SOD1,PPM1G,DVL2,SIRT7,SLC2A3,MET,TTI2,CDK1,JUP,TOX4,METTL14,DENND2D,FTH1,ATG16L1,EGLN3,NUF2,HSBP1,POLR3F,PCBP4,CBFB,PHB1,HNRNPD,NQO1,CDK5RAP3,PSMD10,TRAF6,ATG9A,TAF7,NDC80,AP1M1,SAR1B,RBBP7,G3BP1,BAG2,UBE3A,HSPD1,MAP3K11,SNRPE,EZH2,CHMP4C,ASPM,SAP30,ERLIN2,TPD52,RAF1,GPR37,RANBP6,AIPL1,RBBP4,TUBB,ACTB,APOBEC3G,PFDN2,HSP90AA1,SP1,BAX,SENP8,BRCA1,LMNB1,YWHAZ,PRPF31,TOMM40,DSN1,USP13,CUL3,GRB10,GPC1,TERT,TTC1,HADHA,DNAJC3,PRSS23,CRYAB,USP39,PPP1CB,PRDX3,KCND3,AGTRAP,CAND1,FZR1,PREP,MCL1,CEBPG,KPNA1,AQP2,KCNJ10,TUBG1,SHC1,CSNK2A1,COPS5,KARS1,SELENOS,DNAJB2,MEPCE,PHF1,NEDD8,KDM4B,KPNA2,HNRNPK,YIF1A,MAP1B,METTL18,RNF8,TFCP2,DUSP1,UBL4A,TP53,RPSA,INSIG2,RAP1A,PPP1R10,SRC,MKKS,KCTD9,MAP3K3,PPAT,GRPEL2,SGTA,MACROH2A1,RPS3,CREB1,DTL,UBE2H,TLR9,RC3H2,DNAJC10,DNAJC5,ST13,CARS1,AKT1,MAT2A,TRIM32,MORF4L1,GRPEL1,ABCC2,HSPA5,TUSC2,HDAC3,RNF34,NR1I3,BAP1,NBN,RAB29,HEXIM1,UBE2M,SCLT1,HECTD1,CFTR,HSP90AB1,PGR,TCP1,WDR82,SIN3A,CBL,HSPB1,YWHAB,FKBP4,AGR2,YWHAH,CPEB1,YWHAG,OLR1,DDRGK1,IFI16,VDAC1,RUVBL1,RPAP3,DNAJB4,TOP2B,APTX,MOB3C,METTL21A,ISG15,SPG21,SPC24,SNX20,PPP5C,ESR2,PSMD4,TAGLN2,STAT2,TCAP,ZMYM2,DDIT4,VEGFA,LMBR1L,CCDC90B,APEX2,CRMP1,CCT2,RBBP8,KIAA1191,PSMD14,BTF3,BAG3,BRMS1,MYC,EMC1,APPBP2,HSPA8,HDAC5,AKAP1,CD40,XRCC5,KLC2,PACRG,CSNK1A1,PIH1D1,FUNDC1 |
| 4.878e-14 | -30.65 | MAP1B (microtubule associated protein 1B) | protein interactions | 4131 | 481 | 211 | 19454 | 5460 |
PSMB1,AIFM1,SLC25A12,PRNP,HM13,MOV10,H2AC14,SPP1,SLC25A10,TCOF1,GLUL,HUWE1,FARSA,THRAP3,EEF1A1,MAP1LC3B,GGCT,CCT5,APEH,CCNF,ENO1,TUBA1B,EIF4A3,TECR,VIRMA,RPL22,RPL13A,SLC25A4,TUFM,USP14,KPNA6,MAPRE1,SQSTM1,H2BC12,PPM1G,RPA3,SIRT7,IRF7,PDHB,HMGB1,SMC4,CNP,CDK7,PSMC4,RARS1,RPL26L1,LMNA,MAP1LC3A,GJA1,COPS2,PHB1,PSMB5,STK3,CCAR2,HSPB8,CLPX,PSMD3,MAP1S,MARCHF5,AHSA1,HNRNPD,MED4,RPL23,BAG2,HSPD1,SLC25A5,PSMD12,AHCYL1,RBBP7,TNF,FAF2,PPP2R1A,ANP32A,B3GNT2,STX12,OTULIN,EZH2,RPN1,GDI2,NME1,DYNLL1,ACTB,MCM4,MCM3,CUL3,HSP90AA1,PFDN2,ATP1A3,PSMA3,HADHA,CCDC86,ATP5MK,PSMC1,ALKBH3,SLC25A3,CRYAB,PSMB7,ATP5PO,ADNP,COQ8A,CAND1,ELOC,GAPDH,KARS1,RPS2,SNRNP70,SLC16A1,ABCE1,MAP1B,SLC25A11,H2BC14,FKBP8,PSMA5,ATP1A2,KPNA2,WBP11,UBL4A,HBP1,RNF8,PSMC3,SEC61A1,PHAX,PSMC5,MACROH2A1,UQCRC2,RPS3,PSMA6,SMURF1,DYRK1A,BUB3,RPL10L,H2BC9,CFL1,PSMB2,TRIM32,MAT2A,MLF1,UBE2H,RC3H2,EXOSC4,PGK1,RPL27,BAP1,PML,HSPA5,STK38,CFTR,NTPCR,HSPB6,UBE2M,RPA2,H2BC11,EED,SIN3A,PEG10,HSP90AB1,CCT7,EIF2S1,HNRNPL,ECHDC1,TCP1,XPO1,STK4,NT5C2,IFI16,DDX1,HSPB1,MAGOH,DRG1,H2BC17,RUVBL2,CCT8,PSMA2,PSMA1,VDAC1,RUVBL1,SOX2,TNPO2,EEF2,RPL18,TUBB4B,PDHA1,CMTR1,PSMB6,RPL10,PSMD4,ATP5F1B,CAVIN2,PSMD6,BTF3,MYC,CREBBP,SFN,PSMA4,DNAJB6,SERPINH1,CCT2,CKB,FBXW11,ATG3,HSPA8,HDAC5,ARRDC3,SNRPA,FOS,UFL1,STAU1,EEF1G,PAFAH1B1,PPT1,MAP2K1 |
| 4.925e-14 | -30.64 | DDX5 (DEAD-box helicase 5) | protein interactions | 1655 | 498 | 217 | 19454 | 5460 |
NKRF,FAF1,VRK1,THRAP3,SMN1,RIGI,CCT5,FBP1,CD2BP2,MAP2K3,ILF2,RCHY1,SMAD3,SRP14,TOP1,DCUN1D1,MDM2,CDK9,NFKB1,HDAC6,CRBN,INPPL1,RPA3,TCEA1,SQSTM1,KIN,GTF2I,DGCR8,MBD3,PIAS1,SF3A1,RBFOX2,METTL14,LMNA,WTAP,HNRNPH3,EIF4A3,CCNF,RPS20,UBE2I,RTRAF,GSK3A,NDN,VIRMA,CNTNAP1,PPP1CC,GMPS,USP14,AR,NONO,RUNX1,FBXO7,STK24,YPEL5,HNRNPA2B1,MAEA,NUDT5,TRIP4,PRPSAP1,CBX7,G3BP1,TNF,SSRP1,B3GNT2,MAPK10,CHMP4C,EZH2,PHB1,FOLR1,MAP1LC3A,KCTD10,DHX15,NUP35,PRPF19,HNRNPA1,PSMD10,DROSHA,DDX23,CAMSAP2,RB1CC1,FBXW4,PSMA3,HSCB,UCHL3,WDR77,CDKN1A,PPP1CB,PRDX3,EMC9,FKBP10,TRMT6,SNRPD2,SNRPD1,RPL19,CUL3,CUL2,MCM3,RNF40,DCAF4,BRCA1,ILK,SP1,PSME1,NAE1,DHX9,ERO1A,HNRNPK,NEDD8,CAPZA1,MEPCE,PHF1,TP53,MTCH2,WBP11,DNAJC2,PIK3CA,TFCP2,NUPR1,SYNCRIP,CD4,RPS16,CAND1,FZR1,CDC5L,RBM42,MBD5,TMPO,ELOC,CD81,COPS5,SHC1,SNRNP70,NBN,BAP1,RNF113A,DERL1,HNRNPH2,HDAC3,HSPA5,CFTR,AGO1,ZNF326,RPA2,ACACA,DYRK2,HEXIM1,PRKCA,PSPC1,DAPK1,KCTD9,SRPK2,SMURF1,AKT1,MAT2A,CARS1,PRKACB,NR2E1,SPOP,UBE2H,IGF2BP1,PABPC1,CCT8,RPL31,EWSR1,HNRNPF,KRAS,CBLL1,HNRNPDL,DHX38,SUPT5H,EEF2,SOX2,SRSF1,EED,SUMO2,TCP1,SNRPA1,HNRNPL,CCT7,WWP2,IFI16,GSTM3,CTNNB1,DDRGK1,XPO1,AGR2,ARMC8,MGMT,CBL,DDX1,SNRPA,EP300,DDX5,SF3B1,HSPA8,STAU1,UFL1,HNRNPA0,MTF1,FRS3,PIH1D1,EIF4B,CMTR1,SNRNP40,MATR3,RPL10,APEX1,SFN,HNRNPC,CREBBP,MYC,SNRPB,BTF3,PSMD14,CCT2,PRSS1,CDKL2 |
| 5.082e-14 | -30.61 | HNRNPR (heterogeneous nuclear ribonucleoprotein R) | protein interactions | 10236 | 518 | 224 | 19454 | 5460 |
MRPL40,RASD1,HSPA5,MIR107,MIR29A,PML,MIR10B,BAP1,RNF113A,WWP1,RPA2,MIR7-1,MIR21,HEXIM1,MPV17,CAPN1,MIR34B,CD2AP,MRPS21,PSPC1,RPS3,MRPS28,FGFBP1,RC3H2,MRPS16,SPOP,UBE2H,ELAVL2,IGF2BP1,MORF4L1,SMARCA5,GORASP2,HNRNPK,MRPS33,NEDD8,MIR16-2,MIRLET7C,MEPCE,MIR200A,DHX9,MIR9-3,BMPR2,NFE2L2,TFCP2,NUPR1,TP53,STRBP,UBL4A,METTL15,H2AX,MIRLET7G,FZR1,RPS16,CAND1,CDC5L,RBM42,MIR429,SYNCRIP,MRPS9,SNRNP70,MAP4,RPS2,FAM20C,GAPDH,COPS5,STAU1,FXR2,HNRNPA0,UFL1,SNRPA,NGRN,DDX39B,DDX5,EP300,RAB5A,HDAC5,HSPA8,SF3B1,PABPC5,TIMM10,TOMM22,MATR3,CMTR1,MIRLET7B,FBXW11,TMEM179B,HNRNPC,HNRNPAB,MYC,SNRPB,BTF3,MIR155,KRAS,HNRNPF,HNRNPDL,MIR9-2,TOP2B,RBM3,LSM14A,PABPC1,RPL31,RTCB,EWSR1,MIR206,RPS23,MTA2,NCSTN,SOX2,MIR222,SNRPD3,MIR9-1,SUMO2,HNRNPL,SRSF1,MIR214,EED,MIR31,MIR140,MIR221,PEX3,MIR143,WWP2,DDRGK1,MIR29C,CPEB1,MIR7-3,DGCR8,AATF,LSM8,PIAS1,MIR205,RPA3,MIR34C,MIRLET7I,METTL14,GRM2,LMNA,MTRES1,HNRNPH3,RPLP0,ARHGAP1,SF3A1,RBMS2,MIR1-2,EIF4A3,MIR16-1,CCNF,TRIM24,GSK3A,MIR145,IVNS1ABP,PAIP2,AR,TUFM,USP14,RPL26,RUNX1,FARSA,LSM4,SMN1,SEPTIN7,MIR20A,MIR17,ILF2,MIR15A,APOBEC3D,MIR200C,AURKAIP1,MAP1LC3B,LBR,TOP1,ZBTB2,CDK9,RCHY1,CTDSPL2,MIR106B,MIR25,PRR3,MIR34A,CALR,GRSF1,HDAC6,GPC1,MIR106A,FBXW4,DNAJC3,MTX2,WDR77,TAB1,ACTB,MRPL23,MIRLET7D,UBE2S,TRMT6,RPS9,BRCA1,MIR363,CUL2,CUL3,PMPCA,RNF40,MIR98,SSRP1,EIF2D,UBE2A,HNRNPA2B1,MRPS11,CHMP4C,EZH2,POLR2C,NAA15,ACTN4,KCTD10,RPL7,SPTAN1,DHX15,PHB1,MIR7-2,MIR141,DDX23,MIR1-1,MRPS26,HNRNPD,HNRNPA1 |
| 5.336e-14 | -30.56 | ISG15 (ISG15 ubiquitin like modifier) | protein interactions | 9636 | 487 | 213 | 19454 | 5460 |
USP14,ATP5F1A,BRAP,HERC4,AP2A1,MSN,GANAB,EIF2AK2,ENO1,TUBA1B,IFNA10,RPL13A,TMOD3,LDHA,MX1,MYL12B,PSMC4,RARS1,EPHX1,PICALM,LMNA,MTDH,SQSTM1,CLK1,BRIX1,HDAC6,SPATS2L,PSMD7,POR,PSMB1,ALDH1A3,HACD3,CAV1,DDX39A,FBP1,RAD23B,KLHL26,RPL23A,FAF1,PPP1R12A,GALNT2,RIGI,ARF4,TOM1,THRAP3,RNF115,RBM15B,RAB11A,HSP90AA1,MYO6,AP2M1,CYB5R3,RAN,USP5,RBBP4,TAB1,ACTB,AKR1C2,PPP1CB,MYL6,SLC25A3,PSMB7,PSMA3,TXNL1,PSMC1,NSFL1C,UBXN6,PRDX1,PSMD3,RPL23,PPM1B,DDX23,HP1BP3,MRTO4,PSMB4,IFIT2,PSMB5,FOLR1,DHX15,PPIA,CACYBP,ERLIN1,SPTAN1,ACTN4,TXNRD1,GDI2,EZH2,BAG2,JAK1,HNRNPA2B1,HSPD1,SSRP1,FLOT1,RPS27A,G3BP1,CFL1,PSMB2,MLF1,ATP1A1,PSMA6,DYRK1A,PPP1R10,CHMP5,ADRM1,CFTR,SUMO1,GSTP1,PRDX6,PGK1,UGDH,MARS1,GRPEL1,UGP2,ZC3H15,STK38,GAPDH,TPM3,CSNK2A1,DNAJB2,ACOT8,IFNA2,MAP4,RPL24,SMAD4,DSTN,UBE2N,CD99L2,LMAN1,TMPO,MYL12A,CAND1,TAF2,PSMC3,TAB2,DDX42,TFRC,MINDY3,DHX9,TRAFD1,RPL3,RDH11,MEPCE,KPNA2,CSE1L,HNRNPK,PSMA5,UFD1,MLF2,BAG3,PSMD1,SFN,PSMA4,LDHB,SERPINH1,DNAJB6,ZMPSTE24,RPS26,FTSJ3,PSMD14,CCT2,SF3B4,PSMB6,CBX5,PSMD6,MATR3,ATP5F1B,PSMD4,STAT1,QTRT2,PSMB3,PAFAH1B1,LAP3,RPL27A,GTF2IRD1,HSPA8,TAPBP,HERC3,SPECC1L,XRCC5,PYM1,DDX39B,PEBP1,STAU1,EEF1G,PHB2,EMC1,UBE2D3,CTNNB1,HSPB1,YWHAB,DDX1,FUBP3,SRSF1,SIN3A,HSP90AB1,TCP1,LYAR,FAM98A,HNRNPL,EEF2,TRAF2,ISG15,PLS3,DNAJB4,MYO1B,RUVBL2,TOP2B,PABPC1,CCT8,RUVBL1,HNRNPF,PSMA2,PSMA1 |
| 5.336e-14 | -30.56 | RPSA (ribosomal protein SA) | protein interactions | 3921 | 487 | 213 | 19454 | 5460 |
RPL24,SNRNP70,NOL12,RPS2,RPL10A,ENY2,KARS1,PPIL4,CSNK2A1,COPS5,CAND1,RPS16,FZR1,RPS27L,DKC1,RBM42,SURF6,ITGA6,SYNCRIP,CDR2L,RPL32,CD4,DDX42,TFCP2,DNAJC2,NUPR1,RNF8,IMP3,UBL4A,MEPCE,GNMT,RPL17,RPL3,DHX9,SPOP,RC3H2,UBE2H,RPL7A,RPS17,RPL10L,PPP1R10,RPS3,UQCRC2,PSPC1,RPA2,WWP1,HEXIM1,UBE2M,CFTR,RPS15,HSPA5,SNAPC1,RPL27,BAP1,HSPB1,DRG1,PROS1,IFI16,RPL6,WWP2,XPO1,CTNNB1,NGDN,DDRGK1,RPS10,TCP1,HSP90AB1,NKX3-1,RPS23,RPL18,TOP3B,SOX2,RPS7,KRAS,RPS4X,RPL31,PABPC1,EWSR1,PDIA6,FTSJ3,FBXW11,RPS26,RCL1,H1-1,MYC,SFN,BTF3,PSMD1,BAG3,TAX1BP1,CBX5,ESR2,RPL10,APEX1,VDAC2,NUFIP2,PIH1D1,RPL27A,PAFAH1B1,UFL1,HNRNPA0,STAU1,RPS28,SF3B1,HSPA8,HDAC5,YAF2,CRBN,MPHOSPH10,HDAC6,RPL35A,PRNP,TOP1,CDK9,RPL12,RCHY1,KRR1,SRP72,EEF1A1,MAP2K3,RPL15,PAK1IP1,RPS13,EIF3E,FAF1,NKRF,RPL23A,PEA15,CDC73,FBXO7,RPL26,PPP1CC,NDN,ANKH,RPL13A,SLC25A4,VIRMA,RPL22,CCNF,METAP2,CTTN,RPS20,RPS12,METTL14,RPLP0,RPL26L1,CDR2,ZNF574,ATG16L1,RPS14,CDK7,PDHB,HMGB1,RPL4,PIAS1,UTP23,AATF,RPA3,DCTN6,SIRT7,PNO1,HNRNPD,RPL23,HNRNPA1,RPL7,SRSF10,RPL8,FOLR1,RPL9,PHB1,RPLP1,RPLP2,EZH2,RPN1,NGB,SF3B5,RPS11,MAK16,PPP2R1A,RPL29,G3BP1,RPS27A,SLC25A5,PCNA,RPS24,PRND,BRCA1,ZCRB1,HSP90AA1,SP1,RPS5,RIT1,CUL3,NOP16,PDE4B,RPS29,EIF4A2,DYNLL1,RPL7L1,RPL35,RPL19,FAU,RPL37A,SEC61B,RPS9,H2AC1,EMC9,WDR77,GPC1,NOP53,YTHDF1,G3BP2,PSMA3 |
| 5.623e-14 | -30.51 | mRNA 3'-UTR binding | molecular function | GO:0003730 | 257 | 134 | 18094 | 5411 |
MIR495,MIR143,PABPC5,TIA1,MIR106A,MIRLET7I,NOVA1,MIR3173,MIR519D,PCBP4,MIR16-1,HNRNPD,MIR99B,MIR146A,MIR142,MIR873,MIR21,MIR429,MIR1271,RNF20,MIR205,CARHSP1,ELAVL2,MIR455,MIR296,MIR493,MIR135B,UTP23,HNRNPC,PABPC1L,MIR137,SECISBP2L,MIR141,MIR130B,MIR29C,MIR675,MIR193B,MIR200C,PABPC1,MIR153-1,MIR101-1,MIR15A,MIR379,MIR208A,MIR212,MIR384,MIR206,MIR9-1,CPSF1,MIR23A,MIR186,MIR133B,MIR92B,MIR1-1,RNF40,MIR106B,MIR34C,MIR152,MIR208B,MIR361,MIR129-1,CRYZ,MIR708,MIR335,MIR147A,MIR139,MIR183,MIR10B,MIR192,EXOSC8,MIR491,HNRNPA2B1,MIR497,MIR34B,CCT5,MIR185,AUH,MIR145,RBM38,MIR20A,MIR30D,MIR28,MIR769,MIR96,HNRNPA0,MIR130A,MIR448,MIR346,RPS7,MIR374A,BOLL,EXOSC4,MIR195,MIR885,CIRBP,MIR140,MIR17,HNRNPA1,MIR31,MIR298,MIR204,MIR1298,MIR98,MIR144,TP53,ELAVL4,MIR424,IGF2BP1,MIR338,MIR126,MIR100,MIR33B,MIR198,MIR155,FXR2,LARP4B,MIR193A,MIR34A,MIR10A,MIR214,MIR148B,MIR551A,CPEB1,MIR24-1,DDX5,MIR30A,MIR29A,MIR573,MIR105-1,MIR210,MIR339,MIR223,RBMS2,MIR125A |
| 5.744e-14 | -30.49 | TPT1 (tumor protein, translationally-controlled 1) | protein interactions | 7178 | 279 | 137 | 19454 | 5460 |
CAV1,MDM2,PRNP,TOP1,IL18,TMED9,MCL1,UBE2G2,UBE2N,STT3A,EEF1B2,RPL10A,RPS2,SPP1,API5,HM13,CALR,HUWE1,ATP1A2,MLC1,RPL23A,PPP1R12A,RNF181,SRP72,RAD23B,POLR2G,PPP4C,DNAJC2,UAP1,EEF1A1,H2AX,MAP2K3,TP53,BCCIP,RPL22,UBE2L3,RPS20,MACROH2A1,SRP54,EIF2AK2,LIG3,EIF4A3,CCNF,UBE2H,HERC4,MAPRE1,ATP1A1,USP14,DNAJC5,MORF4L1,UBE2K,NBN,PRIM2,RPA3,RPL27,SHOC2,RPLP0,UTP15,SSR1,RPA2,H2BC11,POLR1D,SUMO1,TIMMDC1,TPT1,G2E3,CCAR2,ATXN10,LYAR,RPLP1,RPLP2,MTHFS,MAGED2,NKX3-1,POLR2L,RPL9,NDUFB8,HSPB1,BCL2L1,BPNT2,AGR2,RFC3,UBE2A,RPS4X,MCM6,RBBP7,UFM1,KRAS,DNAJB4,TMT1A,PABPC1,RPL31,UQCC2,JPT2,SART3,POLR2D,RBPJ,EXOSC3,EZH2,RPN1,RPS7,SOX2,TPD52,USP5,PRRC2A,RPL10,APEX1,UBE2V2,GGPS1,MCPH1,POLR3B,FAIM,FAU,RIT1,RPS26,H2AZ2,H1-10,FAS,UFD1,BAG3,NDUFB6,APOBEC3B,UNC45A,TRIM52,MCMBP,PAFAH1B2,ATAD1,CCDC86,HSPA8,XRCC5,TMEM106B,LACC1,MAP2K1,PCLAF,UBAC2,ZC3H14,RPL27A |
| 5.791e-14 | -30.48 | GRSF1 (G-rich RNA sequence binding factor 1) | protein interactions | 2926 | 510 | 221 | 19454 | 5460 |
RAB3A,NEUROD2,HDAC6,SPATS2L,ISYNA1,MOV10,MRPS23,MRPL24,DBT,MRPL50,TOP1,PRNP,MIR25,PWP2,RPL12,AIFM1,MIR106B,SRP72,MRPL49,ILF2,NDUFS3,LLPH,BCS1L,MIR200C,PPIF,MRPL11,NDUFA2,FASTKD5,MRPL22,MRPS18C,HSD17B10,RPL23A,RING1,NKRF,CASC3,AR,TUFM,PYCR2,CSK,RPL13A,ACAT1,EIF2AK2,MRPL53,CCNF,MTRES1,HNRNPH3,RPLP0,MRPS34,MIR1-2,MRPL20,POLDIP2,BRIX1,RPL4,MRPL17,NF2,MIRLET7I,FADS2,MIR205,MRPS26,HNRNPD,PSMD10,RHOG,MRPL18,HNRNPA1,MRPS35,CLPX,MTRF1,HMGA1,NDUFS8,PPIA,RPL7,NOP58,GATD3,PHB1,MRTO4,NDUFS6,GTF2E2,NUP153,RAF1,IMMP2L,SSRP1,SRSF4,MRPS17,ETFA,ATP5F1D,MRPS11,COX8A,HINT2,HNRNPA2B1,HSPD1,DCAF4,MIR98,CUL2,PMPCA,PYCR1,CUL3,MTG2,AUH,NDUFAF4,PRRC2A,MIRLET7D,MRPL23,RAN,TRMT6,NDUFA5,H2AC1,ATP5PO,CMAS,G3BP2,YTHDF1,NOP53,HSCB,HADHA,EXD2,RPL10A,SNRNP70,CHCHD1,LYPLAL1,SURF6,MALSU1,DKC1,MIRLET7G,FZR1,CAND1,ALYREF,RPL32,MGME1,SYNCRIP,MRPS9,SSBP1,GFM2,RBM34,METTL15,MRPL47,ATP5PB,MIRLET7C,MEPCE,TOLLIP,MRPS33,DHX9,ERO1A,MRPS18B,RPL3,MRPL52,UBE2H,OAT,ELAVL2,IGF2BP1,IRF6,RC3H2,MRPS16,NDUFAF2,RPF2,SRPK2,MRPS21,MACROH2A1,MRPS28,RPS3,CYC1,UTP15,QRSL1,NDUFAB1,CDC42,MRPL10,GRPEL1,MRPL40,MRPL41,NME4,WDR3,GFM1,RNF113A,HCFC2,THUMPD1,MIR31,DDRGK1,NDUFV2,DDX50,IFI16,MIR9-1,HNRNPL,ISG20L2,FUBP3,RPL18,RHOBTB1,NDUFA12,PDHA1,NUDT19,SOX2,H1-3,ETFB,TOP3B,HNRNPDL,RPL28,KGD4,CHCHD2,MIR9-2,H1-10,FTSJ3,MRPS25,HNRNPAB,MYC,CNRIP1,ESR2,ATP5F1B,MRPL13,MIRLET7B,CCDC90B,MTG1,DLST,TACO1,MRPL12,SYK,MRPS7,STAU1,TRA2B,EIF1B,FXR2,UFL1,NDUFS2,EP300,NGRN |
| 5.807e-14 | -30.48 | NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase) | protein interactions | 4905 | 222 | 115 | 19454 | 5460 |
VTI1B,SNAP25,STX6,FUNDC2,CD28,CDC5L,HRAS,COQ8A,EIF3E,DUSP19,GNMT,MAP1B,RAB1A,STX8,STX18,ERG28,SNAP23,NUPR1,TBK1,SNAP29,RAB14,COPE,RHOJ,IDE,VIRMA,VAMP3,CCNF,SCAMP2,STX10,GNPDA1,NAPA,REEP6,AKT1,AKT3,FOXA3,VAMP5,EXOC5,GORASP2,NAPG,TOMM20,GABARAP,BAP1,RPA3,PML,GRIA2,RTN4,RAB9A,RPA2,VPS4B,FGFR1,UBE2M,SCLT1,HEXIM1,CSNK1G3,SEC22B,CDC42,GABARAPL2,CRYM,RAB1B,RHOH,RAMP3,EGLN3,COX14,PSME2,FBXO32,DUSP6,PHB1,STX5,RPLP1,RHOG,STX1A,POU5F1,BABAM1,MRPL9,KRAS,VAMP8,VAMP2,PTRH2,STX12,MOB3C,SOX2,STAT1,TSN,DES,ESR2,LMBR1L,SENP8,BRCA1,RHOB,NTRK3,SCFD1,RIT1,CUL3,HNRNPAB,STX16,GALE,GABBR1,GOSR1,ADRB2,STAU1,STX7,SAP18,HSPA8,BET1L,RAP2A,NUP50,EP300,IRF2BPL,PRKAB1,TOMM22,PGRMC1,BET1,GOSR2,YIPF5,DUSP22 |
| 6.079e-14 | -30.43 | biological process involved in interspecies interaction between organisms | biological process | GO:0044419 | 1540 | 584 | 18204 | 5365 |
IL23A,MOG,SAMHD1,LYZ,BNIP3L,TICAM1,TLR1,MIRLET7I,IVNS1ABP,ALPL,SMARCB1,MECP2,CCT5,CAPN2,IFI16,OPRK1,NDUFAF4,TLR8,ACTR2,BPIFB1,STOM,TRIM10,CCL1,PQBP1,IRF1,PRKRA,PDCD4,LGR4,TMEM45B,CAMP,IL17F,CD47,TAB2,IFNG,FAU,SERINC3,ICAM1,CD58,HEXIM1,COTL1,ZNF175,PHB2,RNASE4,FASLG,TFEB,TRIM21,MIR140,PDE4B,NECTIN2,REG1B,PIK3CG,IL18,EXT1,PRDX1,PPID,TRIM35,DAG1,NT5C3A,SRC,NFKB1,KCNJ8,RNASET2,ARG2,CCL4L1,FOS,SEMG2,CCL2,PSPC1,TASL,TUBB,PML,SFTPD,CCL19,VAMP3,TLR5,DPP4,NINJ1,CDK4,JPT2,TRIB1,CYRIB,TBK1,BPGM,XRCC5,CD2AP,APOBEC3A,THBD,TLR10,TICAM2,MIR222,RARRES2,TLR2,RAB5A,TRAF6,PLSCR4,TRIM32,KLRC2,DEFB115,TUSC2,GPAM,TFRC,YES1,LACRT,NPC2,TRIM62,LAMP3,SARM1,ATG16L1,CD2,IFIT2,LGALS8,RNASE9,SMAD3,S100A8,FCGR2B,NFKBIL1,TRIM5,STAP1,APOBEC3C,NLRP1,CCR4,CH25H,CLU,SYK,OTULIN,CCL23,RAB14,CD40,WDR83,CDC42EP4,RBBP9,CD80,CHMP2B,HP,CD36,TPT1,OPTN,POLR3F,VPS18,PMAIP1,LDOC1,RIGI,SIN3A,IFI27,CHMP2A,LYAR,PC,NMI,CLEC6A,AQP4,DHX16,LILRA2,CXCL3,FABP4,DNAJC3,EEF1G,IFNA2,MIR21,CDC73,IFNK,ATG7,PCK2,TLR9,TNFRSF1B,JAK1,SH2D1A,OCIAD2,MGST2,LEAP2,SYNCRIP,EXOC1,WFDC5,IL6,GTF2F1,RSAD2,PI3,RTP4,BAX,CHMP1A,MMP9,CD86,PYDC2,IFNA10,LSM5,PAIP1,MIR223,G3BP2,CXCL9,FOXP1,TREML1,SLC7A1,IL12B,MX2,FCER1G,DDX1,RNASE6,RNASEL,POLR3B,FGR,EEF1A1,RPL39,CXCL14,DAPK3,PELI1,ST13,IFNGR1,JUN,VPS26B,TRIM34,TMED1,MATR3,HSPD1,ENO1,LDLR,MX1,FOXP3,CD274,PRKCE,MIR545,LACC1,DIO2,RAB27A,DEFB114,KRT8,STXBP1,JAK2,TAF11,TSG101,LYZL6,BCL2L1,MIR187,NRP1,TIRAP,BST2,STAT1,ACP5,MIR221,MIR130A,PSMC3,PLAA,MIRLET7B,NUP153,CNR1,TMEM229B,UBE2N,KLRD1,TOLLIP,RPL13A,SIVA1,CREBZF,CDC42EP2,XBP1,TUBB4B,EIF2AK2,CD14,BAK1,MIR95,HYAL2,GSTP1,TNFAIP3,GPX1,CXCL11,CCL24,TMEM106A,UBE2W,PPP1R11,SAP30,RPSA,NFKBIA,ROMO1,EP300,CALR,MIR675,FBXO9,TLR6,IFNA13,ITGA2,ISG20,TANK,SELENOS,ITGB5,CEBPE,ZMYND11,DEFB129,IL1B,AKT1,B2M,YTHDF2,DROSHA,EPO,LGALS3,CNOT7,TRIM15,SDHAF4,CYP27B1,GAPDH,SLC17A5,GPM6A,RBCK1,IKBKB,IL34,CHMP4C,PPARG,SLC15A2,CXCL13,SP1,APOBEC3H,LYG2,PTGER4,TRIM52,F11R,NQO1,TSPO,IRAK4,CHMP5,TNFAIP8L2,CLEC7A,IL21,AZI2,IL13,H2BC12,CNP,VPS4A,SOD2,ENDOD1,CXCL8,LYZL4,RGS1,TP53,SPAG11B,IDO1,ARF1,CCL8,CCL11,MICB,TOMM70,TLR4,SEC11A,IFI6,TRIM27,NONO,CDK6,SEC14L1,PRDX2,UGT1A1,MIR26B,ITGAV,TMEM33,PPIB,BPIFA2,HSPA8,CHMP1B,CASP4,CCL18,PTGER1,CITED1,TRIM23,NLRP2,CGAS,LSM14A,TNFRSF14,VAMP2,CXCL10,APOBEC3B,LRAT,CDK9,MIR105-1,AIF1,F2,TIFA,IRF4,CLDN3,MAPKAPK3,FBXO3,PLSCR1,PDCD1LG2,CSNK2B,MIR17,PPM1D,CEBPG,CCL25,NLRP3,TRAF2,CX3CR1,NMBR,AVPR1B,PHB1,LY96,TRIM6,PDE12,PSMA2,VAMP7,TNF,ADIPOQ,PLAAT3,DEFB121,XCL1,IL10,ROCK2,PTGFR,RBPJ,CX3CL1,RAF1,CXCR4,ITGB8,RNF5,BATF,DUSP10,IL1RAP,GPR15,HRAS,PYCARD,PLG,ZDHHC8,MBL2,CD1D,HMGB1,CXCL12,PLAC8,EPHA2,HSP90AB1,TAX1BP1,RAB1A,ZYX,ODC1,PIM2,POLR3H,MEF2C,MSRB1,CAV1,IFNB1,TRIM11,NCR3LG1,CHID1,MAVS,CCDC186,CLDN1,IDE,APOBEC3F,CD46,RNASE1,MIR146A,CD81,NLRP9,CD4,PLPP6,TRIM26,SLPI,IRF9,GFI1,IFIH1,SNX3,WWP1,MIR342,MIR421,MYD88,IER3,CCL17,PTGER2,PRDX3,HSPB1,APOBEC3G,MIR142,PPIA,DAPK1,CDC42,IFNAR1,SLC20A2,CNPY3,CCL5,G3BP1,WWP2,TLR3,TRIM68,DEFB124,AKAP12,IRF3,STX8,HSP90AA1,CSF2,CFL1,AKAP1,RNASEK,TNFSF8,MIF,APOBEC3D,CCL3,BPIFB3,RAB9A,CDK1,PELI3,MOV10,LILRB1,SAP30BP,ELMOD2,HTR2A,BCL10,REN,INPP5K,IL12A,CLDN6,HDAC5,MRC1,IRF8,SHC1,CHGA,FOSL2,LTA,MAP3K14,CCDC92,OAS1,REG1A,NUCKS1,FCGR1A,TLR7,IRF7,H2BC11,NLRP6,ZBED1,USP14,CTSB,DHX15,TRIM29,CAV2,TMEM255A,ATP1B1,BECN1,IFI35,BANF1,CYP1A1,LITAF,CCL21,CYBC1,MIR20A,CSNK2A1,EXOSC4,HNRNPA0,TRIM22,STAT2,CBL,FAM3A,CCR5,DEFB116,RAB29,FGF10,GJB2,DEFB1,CLDN9,JAGN1,TRIM8,IL18BP,NCK1,LIAS,TF,ACTA2,CD209,NOTCH2,SRPK2,PLSCR3,MAP2K3,IL1A,CLPB,FCN2,ISG15,DDIT4,CCR7,VPS4B,UAP1,HCFC2,MTDH,CST11,WFDC13,CCL20,JCHAIN,CXCL1,PTPN22,NFKBIB,WASL,IRF2,TTC4,C1QC,FMO1,VAMP8,DHX9 |
| 6.185e-14 | -30.41 | DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2) | protein interactions | 27000 | 212 | 111 | 19454 | 5460 |
RPLP1,RPLP2,RPL8,RPL9,TNIK,HYPK,RPL7,EIF2S1,RPS10,HNRNPA1,RPL6,DICER1,RPL23,DRG1,AHSA1,DRG2,SFTPD,SKIC8,RPS24,SEC11A,PABPC1,RBM3,ABCF1,FKBP2,RPS4X,RPL28,GTF2E2,RPS7,NAA15,RPL18,RPS11,RPS9,RPL37A,EIF3K,RPL10,RPL35,USP16,RPS26,RPS5,MYO6,H1-10,DDX5,HSPA8,RPS28,PYM1,STAU1,UFL1,NEK7,GKAP1,MTF1,RPL27A,RWDD1,RPL32,RPL12,RPL35A,MZT2B,RPL10A,RPS2,ECD,SMAD4,DHX9,RPL3,SLC16A1,RPL23A,RPL17,PSEN1,RPS13,RPL15,IPO8,RPSA,H2AJ,NAA35,ILF2,RBM34,RPS20,PTEN,RPS12,SRP54,EIF2S2,CCNF,CCSER2,RPS3,SRPK2,RPL22,RPP25L,RPL13A,ZNF622,RPS17,MTPN,BRAP,RPL7A,HSPA14,UBE2H,MAPRE1,IGF2BP1,EIF3G,MTDH,BANF1,RPL27,HSPA5,ZC3H15,RPL4,EIF5B,RPS15,MND1,TPT1,ATG16L1,RPS14,RPLP0,RPL26L1,HSP90B1 |
| 6.317e-14 | -30.39 | PSMA2 (proteasome 20S subunit alpha 2) | protein interactions | 5683 | 207 | 109 | 19454 | 5460 |
PSMG2,CRBN,NME2,PSMD7,ZNF24,AMT,TPM3,FZR1,ASB11,CAND1,CDC5L,PSMB1,PSMC3,RAD23B,INSIG2,HADH,EEF1A1,PSMB9,PSMA5,HUWE1,NEDD8,SEM1,PSEN1,MEPCE,PSMB10,FKBP8,MAP1B,PSME1,ABCE1,CACUL1,TXNIP,PSMG3,PSMB2,FBXO7,AR,USP14,ADRM1,UBB,VIRMA,PSMA6,PSMC5,RPA2,GRM2,UBE2M,HEXIM1,PSMC4,PAAF1,CFTR,DESI1,FBXW7,HSPA5,BAP1,RPA3,SOD1,PSMG4,SYVN1,ELP6,AGR2,PSMD10,MED4,RB1CC1,PRPF19,PSMD3,WDR11,DDRGK1,DYNC1I2,SNRPA1,CCT7,NUP35,HSP90AB1,DHX15,PSME2,PSMB5,PSMB4,HOMER3,PNMA2,MOB3C,ISG15,KRAS,PSMA1,PSMA2,PSMD12,UBE3A,POMP,PSMD14,RIT1,SERPINH1,MYC,PSMA4,PSMD1,BAG3,PSMD4,MBL2,PSMD6,TENT5C,PSMB6,CLIC4,ESR2,NFKBIA,MED23,PSMB7,PSMB3,PSMC1,DDI1,RANBP10,SKP1,FBXW4,HSPA8,PSMA3 |
| 6.527e-14 | -30.36 | PGK1 (phosphoglycerate kinase 1) | protein interactions | 5230 | 282 | 138 | 19454 | 5460 |
PPTC7,SPOP,UBE2H,NAPA,PSMB2,AR,ATP5F1A,MRPS21,NDN,LDHA,VIRMA,PSMA6,ENO1,CCNF,PTEN,MSN,TRIM24,COX6C,RPA2,LMNA,SHOC2,UBE2M,SH3GLB2,HEXIM1,CFTR,MRPL10,PML,SIRT7,BAP1,RHOU,INPPL1,SOD1,RPA3,BECN1,FBXO34,EMC4,PGAM1,CALR,GAPDH,CSNK2A1,COPS5,HDAC6,MIF,CAV1,SSBP1,PSMB1,AKR1B1,ARPC3,DISC1,TFCP2,CBX3,MRPL33,H2AX,EEF1A1,HSPE1,CSE1L,TGFBR2,HUWE1,RIGI,MRPL22,MAP1B,FAF1,TAGLN3,EMC2,YWHAZ,BRCA1,COX16,HSP90AA1,LDHB,CUL3,SFN,MYC,BAG3,ATG101,ACTB,TENT5C,TUBB,TAGLN2,ESR2,ENO2,CDC7,PPT1,ACAA2,PIH1D1,AKR1A1,MFAP1,NEK7,OXCT1,BOLA2B,GPC1,MRPL57,UCHL3,ARL6,NRBF2,CSRP1,PEBP1,LCA5,DDX39B,PSMA3,RAB5A,YAF2,NUP50,HDAC5,ATP5IF1,AGR2,SKIC8,HNRNPD,UCK1,PDIA3,CRIP1,CTNNB1,HNRNPA1,PPIB,SUMO2,HSP90AB1,PRKAG1,NGB,CHMP4C,EZH2,SUPT5H,B3GNT2,RAF1,MSX2,EEF2,TUBA1A,ISG15,SOX2,GNL1,KRAS,LASP1,PCGF3,ANP32B,RAD21,HNRNPA2B1,MRPS11,UBE3A,PCNA,EWSR1 |
| 6.676e-14 | -30.34 | PSMA6 (proteasome 20S subunit alpha 6) | protein interactions | 5687 | 290 | 141 | 19454 | 5460 |
DESI1,FBXW7,BAP1,SOD1,SQSTM1,DERL1,RNF113A,PGK1,SYVN1,EXOSC4,METTL14,HSP90B1,GRM2,CDK1,UBE2M,HEXIM1,UBA52,CCND1,PSMC4,ATG16L1,SF3A1,CCNA2,PAAF1,CFTR,XBP1,ADRM1,VIRMA,PSMA6,RPS3,CCNF,PSMC5,SPOP,PSMG3,UBE2H,ATP1A1,NAPA,XPOT,PTPN11,CEP85,CCNB1,PSMB2,AR,USP14,RACGAP1,FBXO7,RBCK1,PSMA5,HUWE1,SEM1,NEDD8,CAPZA1,FKBP8,PSEN1,MEPCE,PSME1,MAP1B,RAD23B,PSMC3,RNF8,CCT5,CDK4,KBTBD4,NAA35,EEF1A1,MAP1LC3B,PSMB9,PRNP,FZR1,PSMB1,PSMD7,PSMG2,DNAJB2,CALR,TPM3,COPS5,UFL1,SKP1,PSMC1,DDI1,PSMA3,TXNL1,HSPA8,PPT1,PSMB7,PSMB3,MBL2,PSMD6,TENT5C,TSN,PSMD4,ATP5F1B,ERH,ESR2,PSMB6,PSMD14,BRCA1,POMP,RIT1,PSMA4,MYC,ZNF596,BAG3,PSMD1,PSMA1,KRAS,PSMA2,SMCO3,RPS27A,PSMD12,HNRNPA2B1,CCT8,ALKBH4,UBE3A,CHMP4C,EZH2,LIMD2,MOB3C,RANBP1,B3GNT2,RAF1,ISG15,ACTN4,SOX2,SNRPA1,CCAR2,PSMB5,POLR2L,PSMB4,PSME2,COPS2,AGR2,PSMD10,ELP6,PPP3CA,DRG1,HSPB1,RB1CC1,PSMD3,DDRGK1,WDR11,YWHAG |
| 6.762e-14 | -30.32 | regulation of intracellular signal transduction | biological process | GO:1902531 | 1832 | 680 | 18204 | 5365 |
TRAF6,GADD45A,TLR2,FKTN,TICAM2,NDP,MIR181D,CD2AP,LAMTOR1,DUSP9,TBK1,CYRIB,JPT2,PPIF,GRM2,DIRAS1,CCL19,NUP62,PML,JMJD8,MAPKAPK5,PDE2A,NHERF1,NPSR1,MAP2K6,NPPC,CHI3L1,HCLS1,DUSP6,PSD2,OPRL1,PIH1D1,DRD1,CHN2,MIR16-1,WDR83,TXNDC12,MINAR1,CD40,ARFGEF1,TMBIM6,FGF16,CLU,SYK,MIR205,CREB3,STK11,CCAR2,ADIPOR1,STK38,TRIM5,ATF3,RGL2,NFKBIL1,FBXW7,NKX3-1,ZDHHC17,FCGR2B,S100A8,RPS7,NOG,PRR5L,KCTD10,MIR101-1,MIR24-1,DUSP22,SPTBN1,ALKAL1,KBTBD6,GIT2,TRIM62,SELENOK,LACRT,DUSP1,BIRC2,TFRC,TAF9,CCN3,TRIM32,RAP1A,PIK3AP1,YWHAZ,OSM,PRKACB,PIK3R2,CUL3,CCNB1,SHOC2,RXFP2,OPRK1,NTRK3,MIR218-1,LMO3,NTRK2,FGF23,BMPR1A,NDC80,CARD19,IVNS1ABP,PPM1B,PRMT6,AKR1C2,NFE2L2,TICAM1,FBXO7,NF2,LAMTOR2,MIR29A,ADGRG1,RALGAPA2,BMPR2,IL23A,SEMA7A,VEGFA,SRC,SH3BP4,ADRA1A,MIR34C,DAG1,ANGPT1,LAMTOR3,PRDX1,RB1CC1,IL18,PIK3CG,ATF4,EPS8,MIR140,TRIM21,HNRNPK,LEP,FASLG,SQSTM1,TNFAIP8L1,RNF41,PHB2,HEXIM1,SCHIP1,ICAM1,SERINC3,TAB2,NLGN1,DOK5,TCIM,BIRC5,ARHGAP5,MIR34B,PAFAH1B1,GPR37,F7,TIAM1,PIK3CA,MIR15A,P2RY12,PDCD4,ROCK1,PRKRA,MIR206,EIF2AK2,FAS,GNAI2,KIT,XBP1,ADRB3,MET,RRN3,MIR497,TRIM24,AR,UBE2D1,DIRAS2,SOD1,CARTPT,UBE2N,CRKL,ARRDC3,TGFBR2,MIRLET7B,MIR130A,PAK2,MIR221,IRAK1BP1,TTI2,STAT1,FGF1,BST2,PLA2G5,TIRAP,NRP1,PIP5K1A,TFG,BCL2L1,PPP3R2,JAK2,PTEN,PPP5C,P2RY10,FGD2,BAD,DEFB114,PARL,SSX2IP,SYVN1,RAMP3,DVL2,CDK5RAP3,GLCE,GSK3A,CRY1,PRKCE,MIOS,NOP53,AKT1,TGFB3,IL1B,STARD13,MIR182,ZMYND11,UBE2V1,WNT7A,PPP3CA,ARFGAP1,RPL26,SELENOS,TANK,SMAD4,ARHGAP15,DRD3,GABARAP,DUSP26,PRMT5,AGR2,TLR6,MIR92B,TMED4,FBXO9,MIR675,SIRT7,CALR,BOK,EP300,LPAR6,NFKBIA,IGF1,SGMS1,SPRED1,VDAC2,PDCD10,UBE2W,KICS2,INPP5E,TMEM106A,MT3,GPX1,CTNNB1,GH1,TNFAIP3,GSTP1,HYAL2,TXN,PEBP1,MCL1,HACD3,GLIPR2,UBE2B,TLR9,PLCB1,HDAC3,RTN4,TNIK,MIR21,PPP1R10,VWF,MIR519D,CPNE1,NACC2,MIR375,SEMA4C,MIR204,CLEC6A,PEX5L,SIPA1L1,SAR1B,NMI,EDNRA,RRAGB,VAV2,DSTYK,GPR65,NDUFS3,UCN,PMAIP1,LPAR2,OPTN,CD36,TPT1,FAM89B,AKT3,ENO1,MIR885,TRIM34,PPP2CB,PRL,MIR186,FLOT1,GPR137,CDC42SE1,PPARA,PELI1,OR2AT4,GPR37L1,PAK5,TRAF7,PRNP,SPRY1,GRM1,HAX1,ADRB1,IQSEC1,NEUROD2,GRAP2,MIR449A,FGR,MIR185,DDX1,IL12B,UBE3A,DNAJC27,TMEM100,MIR223,YWHAG,PTP4A3,CD86,PYDC2,MMP9,GADD45G,UBB,BAX,TRAF3IP2,USP2,STAMBP,ERP29,NDST1,CSK,IL6,MOB3B,CASTOR2,NLRP3,ACVR1,PRKCA,GJA1,DDR1,MIR17,CSNK2B,RHOH,ARF6,TIFA,F2,HAPSTR1,TMSB4X,SPHK2,ZNF622,RELL1,PSMD10,RPF2,TBC1D10C,TNFAIP1,MIR424,GPR89A,NPY5R,NLRP2,PTPMT1,RNF152,ILK,NKIRAS2,EID2,FBXW11,HFE,EPHA2,CXCL12,RHOU,BCL6,RGS2,CDC42SE2,MAPRE2,FGF7,HMGB1,CXXC5,MIR23A,PYCARD,HRAS,AGER,LURAP1,PLEKHF1,DUSP10,EMILIN1,ARHGAP12,FBP1,RAF1,CX3CL1,ROCK2,IL10,MUL1,MAP3K11,FGF3,TWSG1,LBH,FGF17,ADIPOQ,TNF,EDA2R,TRIM6,RPS3,PHB1,RPA2,AVPR1B,TRAF1,SEC13,CX3CR1,MIR145,TRAF2,MSX1,PPP2R1A,SESN2,GPNMB,RELL2,SLA2,HOMER3,IRAK4,ZNHIT1,TNFAIP8L3,KLHL22,HELLS,RAP2A,F11R,TRIM52,CCDC22,CSNK1A1,F10,RPL23,PAQR3,UFL1,RACGAP1,MLF1,PPARG,MIR503,IKBKB,IL34,RBCK1,GAPDH,TRIM44,SIAH1,TRIM15,HINT1,C1QTNF1,S100B,TPBG,EPO,EZH2,CHRNA7,OSBPL8,RPS20,MIR195,MIRLET7G,PYCR1,GHR,ADORA1,FGF22,PTPN1,NKIRAS1,ARHGAP1,FGFR1,P2RY1,ACKR3,TMEM33,ITGAV,MIR26B,PRDX2,NONO,DDIT3,FAM13B,RPS15,TLR4,APLNR,PTPN11,PIP4P1,STK4,LCMT1,SPPL3,TP53,MIR133B,SDCBP,DIPK2A,RRAGA,LPAR1,TNFSF10,MDM2,DDX5,ARHGAP21,MIR34A,SOD2,AZI2,CLEC7A,AVPI1,SYNJ2BP,MAP3K3,NDFIP1,CBL,ANKRD6,SOX9,RHEB,AIP,HCST,ARHGAP25,TRIM22,PROK1,RGN,MIR20A,GHRL,CCL21,PICALM,LITAF,DLG1,IGBP1,IFI35,SNAI2,BECN1,LTBR,FIS1,ACTN4,CYTH2,CAV2,RIT2,DHX15,KDM1A,ATP2B4,SLC38A9,MIR200C,MAD2L1,GRAP,MIR29C,NLRP6,FKBP1A,TLR7,COPS5,RAP1B,IGFBP4,SHC1,CCR1,PRKCB,MAP2K1,DKK1,DYRK1A,RABL3,FEM1B,CA8,COL3A1,PDE8A,NFKBIB,PTPN22,SOX2,C9orf72,PROX1,CYTH4,RNF167,MTDH,HAND2,ADRB2,GREM1,SEMA5A,CCR7,CDH13,DDIT4,SETD9,CRYBA1,MAP2K3,DUSP3,IL1A,TGFB2,CHP1,PAK6,PAK1IP1,NOTCH2,KRAS,ACTA2,SPRED2,TLE1,MIR9-1,NCK1,TRIM8,OTUD7B,LTB,SESN3,FGF10,MYD88,GADD45B,BRCA1,HTRA2,OPHN1,CYTH1,TMEM127,ARHGAP19,HSPA5,CNKSR3,ZMPSTE24,LDLRAD4,ATP2C1,TRIM26,HBEGF,CD4,CD81,LILRB4,MIR146A,ARL6IP5,MTM1,MIR149,IGFBP3,GPBAR1,TAB1,MAVS,RC3H2,TMEM101,DOK4,SLC20A1,EEF1E1,CAV1,ANAPC15,MEF2C,GPR35,CAV3,MSTN,ING2,STAMBPL1,MAD2L1BP,VGLL4,PIM2,SWAP70,CDKN2D,CD28,MYORG,INPP5K,REN,MIR132,BCL10,DDT,HTR2A,TPD52L1,SNIP1,ATP6AP2,CCL3,MIF,OPRM1,RNF34,FBXO8,STK3,AKIP1,BTN2A2,MAP3K12,IRF3,USP15,DYRK2,AKAP12,TLR3,TRIM68,EPHA4,SOS2,DOK6,CCL5,GPR17,CDC42,PPIA,DUSP19,ZFAND6,HSPB1,NUPR1,FERMT2,MYC,FLCN,MIR126,IGF1R |
| 7.006e-14 | -30.29 | SSBP1 (single stranded DNA binding protein 1) | protein interactions | 6742 | 568 | 241 | 19454 | 5460 |
NDUFA12,TUBB4B,NUDT19,PDHA1,NUDCD3,SOX2,MAX,TOP3B,ETFB,HEXA,FKBP2,PAX6,HNRNPDL,KRAS,KGD4,VDAC1,YWHAB,YWHAG,MRPL9,NDUFV2,DDRGK1,ASB1,PNPLA8,HNRNPL,CKS2,PIH1D1,MRPS18A,ACAA2,MRPL12,MRPS7,UFL1,NDUFS2,HSPA8,SF3B1,NGRN,LCA5,XRCC5,FOS,MRPS25,LDB1,BTF3,MYC,LDHB,HNRNPAB,ATP5F1B,PSMD4,SF3B4,MRPL13,VDAC2,TACO1,IRF2,DLST,NUPR1,DISC1,H2AX,HADH,ATP5PB,UBL4A,MRPL47,TP53,MEPCE,MRPS33,PDE12,MRPS18B,MRPL52,ATP5PF,MAP4,H2AC4,SHC1,COPS5,LYPLAL1,GAPDH,COX5A,MALSU1,SPPL3,FZR1,CAND1,SDHB,MRPS9,SSBP1,CD274,COX4I1,MGME1,SCLT1,HEXIM1,CYC1,KLF4,HECTD1,QRSL1,RPA2,SAMM50,NDUFAB1,CFTR,OGDHL,GRPEL1,HSPA5,NME4,MRPL40,MRPL41,TWNK,PGK1,GFM1,DLAT,SNAPC1,BAP1,ARHGEF6,OAT,UBE2H,MRPS16,SPOP,RC3H2,NDUFAF2,PTPN11,ROMO1,MRPS28,MACROH2A1,SSBP3,EZH2,NDUFS6,CHMP4C,NGB,HSDL2,RAF1,CKS1B,MRPS17,UBE2A,RFC2,IMMP2L,SSRP1,TNF,TRIM37,ATP5F1D,ETFA,HINT2,MRPS11,COX8A,PREPL,HSPD1,THNSL1,BCKDK,HNRNPA2B1,RB1CC1,MRPS26,HNRNPD,LHX2,RHOG,MRPL18,HNRNPA1,MMUT,CLPX,MRPS35,STOML2,EGLN3,NDUFS8,GATD3,PHB1,ELF5,NDUFA5,ATP5PO,KLF3,OTULINL,PYGB,HSCB,ATP5F1E,HADHA,SP1,HSP90AA1,ILK,ARHGAP19,TAFAZZIN,YWHAZ,NOA1,HNF1B,CUL3,PYCR1,NDUFAF4,OTUD6A,MRPL23,TUBB,LAMTOR3,MRPL49,UBE2B,NDUFS3,PPIF,EEF1A1,AURKAIP1,BCS1L,FBP1,TMEM126A,MRPL11,NDUFA2,FASTKD5,MRPL22,MRPS18C,HSPE1,HSD17B10,HDAC6,GRSF1,IRF4,DBT,ATP5PD,MRPL24,MRPS23,DCUN1D1,MRPL50,PRNP,AIFM1,PAX9,HNRNPH3,NUDT12,LMNA,CDK1,MRPS34,KLF12,ATG16L1,SF3A1,PIAS1,NHP2,POLDIP2,MRPL20,PDHB,MRPL17,FBXW7,SQSTM1,RPA3,MAPRE1,DNAJC19,FBXO7,ATP5F1A,TUFM,PYCR2,UQCRQ,VIRMA,TXN,SNX3,SLC25A4,ACAT1,ALB,MRPL53,CCNF,TUBA1B |
| 7.483e-14 | -30.22 | RPS25 (ribosomal protein S25) | protein interactions | 6230 | 344 | 161 | 19454 | 5460 |
RPL7A,PPP1CC,USP14,FBXO7,RPL26,RPS17,RC3H2,SPOP,MAPRE1,UBE2H,EXOSC1,METAP2,TUBA1B,PSPC1,RPS3,OPTN,CCNF,RPS12,RPS20,PTEN,RPL10L,RPL13A,RPL22,SMURF1,TPT1,UBA52,RPS14,CFTR,METTL14,RPA2,VPS4B,LMNA,KLF4,RPLP0,HEXIM1,NLE1,RPL27,BAP1,RPA3,RPL4,FBXW7,HMGB1,RPS15,HSPA5,AATF,PIAS1,ENY2,CSNK2A1,CD81,COPS5,HDAC6,SNRNP70,RPL24,TUBG1,CRBN,RPL10A,RPS2,RCHY1,SRP14,PEX5L,RPL12,RPS27L,FZR1,CAND1,RPL35A,RPS16,CDC5L,CDK9,MBD5,RBM42,MDM2,RPSA,TP53,UBL4A,RPL15,THAP1,DISC1,TFCP2,SRP72,RPL23A,ABCE1,RPL3,VRK1,HUWE1,EIF3E,RPL17,RPS13,MEPCE,STAC3,CUL2,CUL3,SFN,MYC,RPS29,BTF3,BRCA1,RIT1,RPS5,RPS26,ICAM1,FAU,RPS9,SEC61B,RPL37A,RPL35,RPL19,RPL10,PAFAH1B1,RPL27A,WDR77,H1-5,CDKN1A,EMC9,PIH1D1,EIF4B,NKAPD1,RPS28,DDX39B,PYM1,HSPA8,STAU1,GPC1,UFL1,G3BP2,WWP2,RPL6,DDRGK1,XPO1,AGR2,DRG1,RPL23,POU5F1,AHSA1,PHB1,RPL9,FOLR1,RPL8,RPLP2,RPLP1,RPL7,RPS10,E2F4,RAF1,RPS7,RPL29,EZH2,RPL18,RPS23,RPS11,RPL31,RPS24,EWSR1,DNAJB4,TRIM37,ZBTB14,TNF,G3BP1,KRAS,RAD21,RPL28,RPS4X |
| 7.768e-14 | -30.19 | MDH2 (malate dehydrogenase 2) | protein interactions | 4191 | 480 | 210 | 19454 | 5460 |
TUFM,ATP5F1A,PYCR2,VIRMA,UBE2L3,LDHA,NDN,ACAT1,CCNF,MRPL53,MTRES1,MRPS34,POLDIP2,MRPL20,PIAS1,YKT6,PDHB,MRPL17,IDH3A,SOD1,RPA3,GRSF1,CALR,MRPS23,MRPL24,ATP5PD,DBT,MRPL50,EEF1AKMT3,AIFM1,MRPL49,MRPL51,PPME1,NDUFS3,BCS1L,PPIF,NDUFA2,MRPL11,MRPS18C,MRPL22,FASTKD5,HSPE1,HUWE1,PC,HSD17B10,EMC2,SFXN1,FAF1,BRCA1,NOA1,YWHAZ,AK3,MRPL16,PYCR1,PMPCA,AUH,MTG2,PARL,NDUFAF4,TENT5C,MRPL23,NDUFA5,CRYAB,ATP5PO,TIMM13,PRDX3,MRPL57,HSCB,UCHL3,HADHA,PSMA3,ATP5IF1,NMRAL1,EXD2,COTL1,MRPS26,MRPL18,RHOG,MMUT,MRPS35,STOML2,PRDX1,PDIA3,CLPX,MTRF1,NDUFS8,G2E3,GATD3,PHB1,NDUFS6,CHMP4C,RAF1,HSDL2,IMMP2L,MRPS17,ATP5F1D,ETFA,TRIM26,UFM1,COX8A,MRPS11,HINT2,PCNA,THNSL1,HSPD1,PREPL,UBE2H,OAT,MRPS16,H2BC9,CFL1,NDUFAF2,KCTD9,MRPS21,PTPMT1,MRPS28,HEXIM1,RPA2,QRSL1,CFTR,MRPL10,NDUFAB1,GRPEL1,OGDHL,MRPL41,MRPL40,NME4,DLAT,GFM1,DERL1,TWNK,BAP1,TRMT5,TMEM70,CHCHD1,LYPLAL1,GAPDH,COPS5,COX5A,MALSU1,MIF,COX4I1,MGME1,ALYREF,MRPS9,CD274,SSBP1,SYNCRIP,SDHB,RNF8,TFCP2,METTL15,HADH,MRPL47,ATP5PB,MEPCE,TOLLIP,HNRNPK,PDE12,MRPS33,IDH1,THG1L,MRPS18B,ATP5PF,MRPL52,SERPINH1,MRPS25,CKB,HNRNPAB,ATP5F1B,PSMD4,MRPL13,TRMT11,CCDC90B,DLST,GLRX2,TACO1,ACAA2,PPT1,MRPS18A,NDUFAF3,MRPL12,ISCU,TANK,MRPS7,PHB2,OXCT1,NDUFS2,UFL1,EMC1,HSPA8,HDAC5,PEBP1,HSPB1,AGR2,DDRGK1,MRPL9,NDUFV2,PNPLA8,HNRNPL,FAHD1,CORO1C,NDUFA12,PDHA1,SOX2,ETFB,HNRNPDL,KGD4,KRAS,PSMA1 |
| 8.446e-14 | -30.10 | NEDD8 (NEDD8 ubiquitin like modifier) | protein interactions | 4738 | 358 | 166 | 19454 | 5460 |
RND2,ASB8,SKP1,NSFL1C,EEF1G,SRSF2,UCHL3,UBE2D3,HNRNPA0,DDX5,PSMA3,YAF2,PMAIP1,HSPA8,RIT1,HSP90AA1,YWHAZ,FBXW11,SENP8,CIRBP,BAG3,UFD1,HMGCS1,PSMA4,HNRNPC,CUL2,HNRNPAB,CUL3,MYC,USP13,COPS7A,RPL19,KBTBD6,ACTB,RPL35,TUBB,MATR3,PSMD4,PHF21A,SNRPD1,HGS,RHOBTB1,KLHL12,RPS23,OTULIN,RND3,GHR,NDUFS6,TUBB4B,MSX2,TULP3,OTUD6B,IMMP2L,CPLX1,HNRNPDL,TFG,COPS4,RAB8B,DCTPP1,GTF3C3,RPS27A,RPS4X,G3BP1,PSMA1,KRAS,PSMA2,HNRNPF,SRSF7,PCNA,EWSR1,PABPC1,HNRNPA2B1,HSPD1,RPL31,ZYX,FBXO3,DCAF11,HNRNPD,DDX1,TST,RHOG,FEM1B,HNRNPA1,FGF1,RPL6,PRDX1,EGLN3,PPIA,RHOH,KCTD10,SPTAN1,HYPK,COPS7B,RPS10,COPS2,RPLP2,RPLP1,IGBP1,CBFB,RPL8,UBE2M,RPLP0,HNRNPH3,CDC42,UBA52,SPTBN1,OR4S2,HSPA5,H2AC13,RPL4,FBXW7,KDM1A,UBE2K,SQSTM1,HNRNPH2,RHOU,IGF2BP1,DNAJC10,SPOP,DNAJC8,BRAP,FBXO7,H2BC9,UBA3,SMURF1,UBB,RHOJ,PRKCE,RPS20,RNF187,PSMA6,RPS3,QNG1,ILF2,RPL15,EEF1A1,TP53,STRBP,HNRNPK,TOLLIP,KPNA2,PSMA5,NEDD8,SEM1,KLHL15,DHX9,RPL23A,NAE1,FAF1,H2AC4,ELOC,GAPDH,KLHL22,COPS5,HDAC6,DNAJB2,KLHL9,H2AC14,PRNP,DCUN1D1,RPS16,KCTD3,SEC23A,SYNCRIP,HRAS,TFE3 |
| 8.613e-14 | -30.08 | PDCD11 (programmed cell death 11) | protein interactions | 22984 | 369 | 170 | 19454 | 5460 |
GRSF1,NFKB1,PLEKHO1,SSBP4,CHCHD1,H2AC4,KPNA1,MIR34A,MIR106B,TRMT10B,GATAD1,MIR25,FZR1,CAND1,RPS16,MIRLET7G,CDK9,MIR429,ZBTB2,SURF6,NOP9,KLF9,TP53,MIR200C,MIR15A,AURKAIP1,RPL15,LLPH,MIR20A,MIR17,MRPL52,MIR200A,RPL23A,HAPSTR1,RPL3,MIR9-3,TOLLIP,MIRLET7C,PTGES3,RPL17,MIR16-2,RPF2,PPP1CC,MECP2,RC3H2,MIR145,ATP1A1,RRP7A,UBE2H,CDKN2AIP,RPS3,MIR16-1,OPTN,CCNF,POP7,EIF2AK2,ZNF330,FGFBP1,PRKRA,RPGRIP1L,RPP25L,RPL13A,RPP25,SRPK2,VIRMA,RPS14,MIR34B,MIR1-2,GTF3C4,KLF12,FGF13,RPA2,LMNA,GRM2,USE1,MIR21,RPLP0,NOL7,E2F6,RPL26L1,KLF4,MACROH2A2,MIR7-1,MIR10B,RPA3,NOG,NLE1,SIRT7,MIR205,MIRLET7I,EXOSC4,RAB9A,MTDH,MIR34C,MIR7-3,RPL4,MIR107,BRIX1,MIR29A,AATF,IFI16,MIR143,NDC80,HNRNPA1,MIR29C,DDRGK1,MAP3K14,DDX23,MIR31,MIR1-1,MIR221,MRPS26,MIR140,LHX2,RPL8,MIR7-2,EED,S100A8,MIR141,MIR214,ISG20L2,MIR9-1,WIF1,CEP19,TOP3B,RAF1,E2F4,MAK16,MIR222,SOX2,LGR4,PAIP2B,HDAC11,CHMP4C,RPL18,RPL31,MIR9-2,FGF3,AKAP14,MIR206,COX8A,RPS24,G3BP1,KRAS,MIR155,RPL28,AUH,MYC,RAB11A,CUL3,MIR98,PSKH1,FTSJ3,DCAF4,MIR363,CDKL2,DNAJB6,RIT1,MIRLET7B,SNRNP40,MIRLET7D,APEX1,ESR2,MTF1,SYK,BET1,APOBEC3C,STAU1,COIL,MIR106A |
| 8.752e-14 | -30.07 | SRP19 (signal recognition particle 19) | protein interactions | 6728 | 241 | 122 | 19454 | 5460 |
RPS7,EEF2,RPL29,TRMT1L,RAF1,RPL18,SART3,RPS23,RPS11,SEC61G,RPN1,RPS24,PABPC1,RPL31,MRPS17,RPL28,RPS4X,KRAS,XPO1,EMC6,RPL6,DRG1,RPLP2,RPLP1,RPL9,RPL8,LYAR,RPL7,RPS10,NOB1,RPL27A,NUFIP2,RPS28,CMAS,G3BP2,SSR3,STAU1,UFL1,RPS29,BAG3,BTF3,NOP16,RPS5,RPS26,H1-10,RPS9,SEC61B,RPL37A,VPS72,EIF3K,DOK4,RPL19,PRRC2A,RPL10,RPL35,MED17,RPL15,MAP1LC3B,IPO8,RPSA,CCDC47,SRP72,ILF2,DHX9,RPL23A,ZC3H11A,ABCE1,RPL3,NKRF,RIGI,EIF3E,RPL17,SMN1,RPS13,MRPL22,SRPRB,RPL10A,RPS2,KPNA1,RPL24,ANKRD49,CAMLG,RPL32,SRP14,SRPRA,RPL12,ZBTB2,RPS27L,RPS16,RPL35A,EIF3J,EDF1,RPS14,RPLP0,RPL26L1,HEXIM1,FGFR1,MTDH,RNF113A,RPL27,BAP1,SOD1,RPA3,BRIX1,ZC3H15,RPL4,RPS15,RPS17,RPL7A,PDCD4,EIF3G,SPOP,RPS12,RPS20,SRP54,EIF2S2,SEC61A1,EIF4A3,RPS3,PSPC1,RPL22,RPL13A |
| 8.936e-14 | -30.05 | EGLN3 (egl-9 family hypoxia inducible factor 3) | protein interactions | 112399 | 1292 | 481 | 19454 | 5460 |
NDUFA5,WDR77,IDH3B,PRDX3,TIMM13,ATAD1,MCMBP,UNC45A,SKP1,NT5C3A,PSMC1,ATP5MK,RTKN,THOC3,NUBP2,HADHA,RNF10,MYO6,PFDN6,DSN1,MCM4,MCM3,RIOK2,SAMHD1,RFC5,RNF40,DYNLL1,UMPS,PARL,GNB1,MAD2L1,CHCHD3,VGLL4,PELO,SLC30A7,RMDN3,LRRC1,CDC7,STIM1,OTULIN,RNF126,GPBP1L1,GNB1L,GFPT1,NUP153,ASPM,TRIM37,RBBP7,UNC119B,NDUFA4,SLC39A7,CAMSAP2,AHSA1,SLC25A21,SAV1,STOML2,PRDX1,PRPF19,PSMD3,CLPX,FEM1B,ATXN10,SNX2,OS9,NDUFS8,CACYBP,ZNF593,WDR6,DNM2,COPS2,TSG101,IGBP1,PBDC1,TIMM23,CDK1,P3H1,PDCL,EEF1E1,WDR83,RBFOX2,PSMC4,ELP3,CNP,SMC4,GTF2I,TMEM209,PNO1,SQSTM1,FLCN,DCAF16,XPOT,NDUFB10,GMPS,PPP1CC,TUFM,NTAQ1,ATP5F1A,ARMC6,TXN,ZNF507,TECR,INPP5K,STUB1,GANAB,RAD23B,TBK1,CCDC47,UBR7,LBR,TOM1,BACH1,SERTAD1,PRDX4,MSH6,CTNND1,TMX3,HSD17B10,RING1,PSMD7,SLC2A1,TOPBP1,SSX2IP,DNAJC7,ISYNA1,GMPPA,GMPPB,LRRC40,MAPRE2,SLC25A12,G6PD,POLE3,DFFA,AIFM1,ETV6,PLAA,PALS2,CTBP1,FDFT1,SUFU,SLC16A10,SHMT1,NDUFAF3,YIPF5,PITHD1,SSR3,EYA3,RNF5,RANBP10,ZBTB5,AKAP1,HSPA8,RBM27,POMP,DNAJB6,POLR1B,MLF2,TIMM21,PSMD6,PSMD4,ATP5F1B,LDB2,TCEAL1,PPP5C,NFKBIA,ZNHIT6,CRKL,ZRANB2,RANBP1,ERRFI1,KIF2A,CRTC2,VDAC1,MAPK1IP1L,CCT8,RPAP3,IKBKB,ANKRD50,DRG1,YWHAB,SYNJ2BP,SIVA1,STK4,IQSEC1,TCP1,DYNC1I2,UQCRH,POLR2L,MAGED2,SAMM50,EIF2B3,HECTD1,ACACA,HEXIM1,SUMO1,NTPCR,CFTR,GTF3C4,KDM1A,UGDH,RNF113A,FAM53C,CALU,ATP1A1,CEP85,NCAPG2,GMDS,PPAT,ADRM1,KCTD9,BUB3,BCCIP,SUCLG2,ZBTB33,ZNF655,PSMC5,IK,TMEM165,ACADSB,TBC1D4,PSMC3,TAB2,MTCH2,IPO8,CDK4,UBL4A,RRM1,PREB,RPAP2,TMEM33,SRPRB,MNAT1,FKBP8,CAPZA1,SLC25A11,NOSIP,NAE1,TRAFD1,SLC16A1,ABCE1,STX18,USP15,CDK12,ZNF24,GPRASP2,CSNK2A1,MIOS,TMPO,NDUFB4,STT3A,COQ8A,AIP,SDHB,MCL1,FEM1A,ISOC1,SLC25A3,ARCN1,NOTCH2,PGRMC1,NDE1,RADX,SRI,FBXO30,EXD2,FAM168B,DUSP9,BIRC2,BRCA1,YWHAZ,ILK,RMI1,PFDN2,SCFD1,PIK3R3,CDC123,TUBB,TAB1,PRDX2,NDUFAF4,ABHD12,CNOT6,IFT172,SEC61B,SKA3,RPN1,IFT22,POLR2C,DTWD2,RAF1,HSDL2,FAF2,JUN,PPP2R1A,ENKD1,TOB2,GTF3C3,MAEA,HSPD1,NEK9,SLC25A5,SKA1,MKLN1,PCNA,PPM1B,DROSHA,DICER1,VPS4A,HAX1,NDC80,ATG9A,SIAH2,AGK,NUF2,STK3,EGLN3,ATP6V1A,DCTN4,HAUS2,TIMMDC1,SEC22B,COQ8B,RABL3,UQCRC1,PIK3R2,PDHB,GID8,PPM1G,RPA3,DVL2,MIS12,ARFGAP3,SDF2L1,YPEL5,CIAO1,HMOX2,RACGAP1,BRAP,CEP97,UQCRQ,CTNNA1,TUBA1B,CTTN,GAB1,SFXN2,NDUFS3,ACTR2,DHRS7B,MLLT11,VAC14,SELENOK,CCT5,CD2BP2,FARSA,DNAAF10,TTC4,NOC4L,TSSC4,CNOT7,SMN1,ABHD10,FASTKD5,TMED1,MRFAP1,ECD,OSBPL8,CNN3,ERCC3,MDM2,NKIRAS2,TOMM70,CDK9,EIF4E2,TIMM8B,PTPN1,WDCP,PSMB1,MYBL2,PPT1,CSNK1A1,TRMT112,TOMM22,QTRT2,ADRB2,NDUFS2,LYPLA2,GPHN,PSMD14,CCT2,SERPINH1,PSMA4,CREBBP,STX16,PSMD1,MBL2,TAMM41,RPL10,POLR2B,VDAC2,PRMT5,GPN2,PTRH2,PDHA1,TUBB4B,SPC24,EEF2,SNAPIN,NAB1,DCP2,PFDN1,FBXO3,FAM168A,MYO1B,CDK5,ARMC8,CBL,CNOT2,CTNNB1,XPO1,SUMO2,SUMO3,AASDHPPT,NOB1,CDK17,CCT7,HDHD5,SSR1,HPS6,LEMD3,CYC1,PAAF1,CDC42,POLR1D,HDAC3,PML,TMEM263,MAIP1,SMG5,GFM1,CISD1,ATP1B3,ATF4,FAM193B,SLC25A1,PSMB2,ARHGAP21,CFL1,EGLN2,DYRK1A,CDC20,MID1IP1,CCSER2,UQCRC2,CSNK2B,SRP54,CAPZA2,SLC25A24,GNAI3,CAPN2,TP53,ATP5PB,ESS2,AZI2,CSE1L,PDE12,NEDD8,NUP107,PSMA5,CLPB,KPNA1,AKAP8L,TAF9,EDC3,ELOC,CAND1,KCTD3,KLK3,UBE2G2,SSBP1,XXYLT1,DSTN,SLC39A10 |
| 9.301e-14 | -30.01 | VDAC3 (voltage dependent anion channel 3) | protein interactions | 7419 | 315 | 150 | 19454 | 5460 |
DPP4,TSPO,CALR,COX5A,ATP5MG,USP15,POR,ESYT1,CD4,SDHB,ITGA6,HRAS,COX4I1,ILVBL,ATP5PD,MYL12A,ZBTB2,ARL6IP5,PPIF,TMEM205,ATP5PB,MTCH2,SLC25A20,NDUFS3,GNG5,ABCE1,FAF1,RAB1A,SLC25A11,PQBP1,FKBP8,GALNT2,TOLLIP,SRPRB,ZNF365,ATP5F1A,USP14,RAB2A,SUGP1,ATP1A1,NRP1,MAPRE1,CALU,SPOP,CISD1,ATP1B3,RIC3,DNAJC10,GANAB,CCNF,MRPL53,UQCRC2,TECR,UQCRQ,VIRMA,SRC,MGST3,NDN,SLC25A4,UQCRC1,CDC42,UBA52,RPLP0,CDR2,MEST,CYC1,RPA2,COX6C,HSP90B1,GRM2,SSR1,STOM,RPA3,PML,DAD1,PDHB,FBXW7,DDRGK1,RAB5C,HNRNPD,NDUFB8,AGR2,CORO1C,ATP6V1A,THY1,PHB1,OCIAD2,NDUFS8,EGLN3,FAF2,TUBA1A,ACTN4,CYB5R1,RAF1,TOP3B,STX12,ITGB5,RAB19,RPN1,PDHA1,COX8A,SLC25A5,NDUFA4,LSM14A,G3BP1,VDAC1,ATP5F1D,TOMM40,CASP4,PCCB,NDUFB7,MYC,RAB11A,HNRNPC,ICAM1,SERPINH1,SPCS3,RBM27,SF3B4,BST2,VDAC2,LMBR1L,CYB5R3,ESR2,GNB1,ATP5F1B,LAMTOR3,ACTB,CD59,TOMM22,FAM8A1,SLC25A3,VAPB,ATP5PO,TMEM256,RAP2A,HADHA,JAGN1,ATP5MK,COIL,FBXL4,ITGAV,GNB4,STX7,G3BP2,UFL1,NDUFS2,SSR3,RER1,PHB2 |
| 9.301e-14 | -30.01 | DARS1 (aspartyl-tRNA synthetase 1) | protein interactions | 1615 | 315 | 150 | 19454 | 5460 |
XPNPEP1,MIR155,TRIM37,VDAC1,EMC8,KRAS,GTF3C3,MIR9-2,AKT2,MIR206,CHMP4C,EZH2,MOB3C,TOP3B,RAF1,ISG15,GFPT1,SOX2,JUN,MIR222,MIR9-1,SUMO2,EIF2S1,HSP90AB1,CHMP2A,MIR7-2,PHB1,MIR214,MIR141,ATP6V1A,MIR31,AGR2,DRG1,MIR140,MIR221,MIR1-1,MIR143,PFDN5,WWP2,DDRGK1,CTNNB1,XPO1,MIR29C,STAU1,UCHL3,UFL1,MIR106A,CRY1,HDAC5,HSPA8,EMC9,BET1,RPL27A,IDH3B,OTUD6A,RPL19,MIRLET7D,MAT2B,DLST,PELO,MIRLET7B,PSMD14,ATG3,BRCA1,RIT1,MIR363,COP1,CUL3,PIK3R3,MYC,ACO2,HMGCS1,MIR98,CSE1L,PSMA5,MIR16-2,MIRLET7C,VTA1,FBXO25,TCOF1,MIR200A,MAP1B,HSD17B10,MIR9-3,RPL23A,RPL3,MIR20A,MIR17,SRP72,COMTD1,RPL15,MIR200C,MIR15A,EEF1A1,MIRLET7G,FZR1,RPS16,G6PD,TMPO,MIR429,SYNCRIP,MIR106B,MIR25,TIAM1,MIR34A,KARS1,MIR7-3,RPL4,FBXW7,NF2,MIR107,MIR29A,MARS1,MIR205,MIR10B,BAP1,SNAPC1,SOD1,RPA3,MIR34C,RNF113A,MIRLET7I,SDCBP,RPA2,MIR7-1,MIR21,UBE2M,RARS1,RPLP0,HEXIM1,CAPN1,EEF1E1,ATG16L1,MIR34B,CFTR,MIR1-2,KCTD9,NDN,VIRMA,MIR16-1,CCNF,MSN,MIR145,SPOP,UBE2H,SEC13,RPL7A,CDC16,USP14,RPL26 |
| 9.543e-14 | -29.98 | MICALL2 (MICAL like 2) | protein interactions | 79778 | 137 | 80 | 19454 | 5460 |
RPL4,PHB2,PDHB,LCN1,RPL27,SLC25A3,RPLP0,CDR2,PPP1CB,H1-5,ATG16L1,RPL27A,RPS14,VIRMA,GNAI2,RPL10,RPL19,RPL35,RPL13A,TUBB,ACTB,RPS9,MACROH2A1,CALML5,DLST,ENO1,TUBA1B,RPS3,RPS26,PSMD14,NONO,RPL26,RPL7A,PYCR1,CUL3,HNRNPC,MYC,RPL17,RAB8B,RPS4X,RPL28,RPS27A,RPS13,SRSF4,HNRNPK,H3C1,G3BP1,ERP29,RPL3,RAB13,TRIM21,RPL23A,LSM14A,HNRNPA2B1,SLC25A5,RPS23,RPL18,RPS11,ILF2,PDHA1,TUBB4B,RPL15,RPS7,EEF1A1,RPL29,ACTN4,ERLIN1,RPL7,RPS16,STX5,RPL12,RPL8,RPL10A,RPL23,RPS2,RPL24,H2AC4,GAPDH,RPL6,STOML2 |
| 9.660e-14 | -29.97 | vesicle | cellular component | GO:0031982 | 4141 | 1396 | 19108 | 5553 |
ACO1,SRPRA,TOLLIP,CHGA,SNAP29,PYGB,NAPG,RAB39B,MIR422A,CDH11,CFAP119,SLC11A2,RPL24,CDC42EP2,SLC25A1,BCL2L1,DNASE1L1,DKK1,MAGED2,CRABP2,S100A10,P3H1,MGP,IL1B,PDE6D,SPACDR,STX6,IL15,TEX261,SCG2,CD86,H2AC4,CLTRN,DEGS1,ATP6V0B,SQSTM1,EMILIN1,RAP2B,YWHAZ,ST3GAL1,SLC22A8,TMEM59,GPR15,PSMC5,CYB561,MEST,ITGAV,CMPK1,COPE,FAM20C,SLC2A1,STMN2,UBE2V1,GFPT1,CD4,DNAJB9,RPL12,CRYM,G6PD,ATP6V1A,TRAPPC14,PDAP1,PPFIA3,SLC38A9,PLG,AKT1,CRB3,CRHBP,ICAM1,GPRASP3,MIR342,CD1C,ATP6V1E2,CXCR1,TNIK,ACTR1A,STK24,TLR4,RPL31,SNAP25,WDR11,DAG1,DLG4,PRKCA,ADD2,CD14,ARF4,GLUL,SIGMAR1,F11R,GSTM2,NIBAN2,WASF3,DLG1,H2AZ2,CHMP1A,FIG4,CTDSP1,YES1,CAMKV,ALYREF,CMA1,GGH,MIR9-1,SLC22A12,SRGN,CD1E,AQP11,VPS28,PLAC8,ANP32B,CASK,MIR193A,OCIAD2,CAPN1,PSMB7,CUTA,OPRL1,SLC35F6,CLIP3,CD47,SUV39H1,MIR197,LAMB2,ABCB9,SFTPC,VWF,TNFRSF1B,EEF1G,SCYL2,PHETA2,TOM1L1,PDE8A,RARS1,CXCR4,GNAI3,AP2A1,RNASEK,PDE4B,FCAR,FASLG,STX11,TBC1D10C,RAB27A,CA2,KCNH1,ENPEP,TRAK2,IL6ST,TLR3,MIR23B,NTF4,SEC13,TMEM165,MIRLET7B,MAN1A2,STX17,SSPN,CD1A,PLD3,ABHD14B,JAK2,SRC,LAT2,CRYZ,LDHA,DDX23,PSMD7,SEC23A,SLC39A13,ATP6V1G1,TICAM1,SLC1A1,DES,AVL9,AMY2B,LYPLA1,PSMD12,SORD,ENDOD1,MMD,CNIH1,STX12,TLR9,NPTX1,PRKCB,CDIP1,CHCHD3,RAB35,DYNC1I1,RHOBTB3,NTRK2,HNRNPK,ENO1,GHITM,SYN3,RAB5C,ATP5F1B,CLEC18A,HSP90B1,RPL10A,STX7,ABHD6,PSMA5,GH1,PSEN1,CNTN1,MIR30A,MMP14,GABARAPL2,FGD2,ERP29,MIR107,MACROH2A2,RAB33B,HGS,GRIA2,B4GALT1,CYSTM1,CD46,CD164,CDC42EP4,AKT2,LACRT,RETN,SLC35G2,CST3,MIR193B,LRRC57,SLC30A7,TRAF2,EHD3,KDELR1,SLC48A1,GLRX,SDC4,MARS1,HCRT,UBL3,PTPN1,RPS16,SNX5,IL2RG,PROS1,SEC22B,SH3GLB1,PSMA3,DISC1,PABPC1L,RAB33A,MIR1304,NPPC,NHERF1,PIP4K2C,SYNGR2,CYRIB,PRSS37,RAP1A,SERPINA1,SAT2,ARMC8,NUDT5,EPHA4,ITM2B,MIR31,VDAC2,CYB5R3,LRAT,GABRA2,MIR143,FCHO2,BLOC1S3,VTI1B,RAB18,NCDN,TM9SF4,RAP2C,SPR,ENPP4,HNRNPA2B1,ACTN4,CLU,ACAP2,CTTN,GRAP2,SCFD1,FOLR1,ALCAM,ORMDL3,REG1A,RPS3,DSN1,CD59,AP5M1,SYP,JUP,AHCYL1,AGA,AP1G2,ABCC5,PSMB3,CFL1,VPS54,UBA52,TASL,DYNLL1,ADRB2,ERG28,TSPO,FCGR2A,PTP4A3,EHD4,HSPE1,DDAH1,MIR221,CD40,DDX5,RAB9B,ACTR1B,CHIC2,TRAPPC2L,RP2,KIT,PRSS23,SERPINB9,ITGB8,PLEKHF2,TMEM198,VPS18,RAB1B,SLC38A1,PLSCR1,SERPINC1,TPM3,SNX11,AGAP2,RAB3A,IDH2,ATP8A1,KCNJ11,RNF133,UGDH,KLHL12,IL12B,HEXA,GNG7,CPNE1,DICER1,ATG16L1,FBLN5,PCSK9,ZYX,H2AX,NRSN1,GJA1,ATG7,CD2AP,TMEM127,TRAPPC10,CAV1,PSMA6,SNCG,SERPINI1,ATP6V0E1,CDC42,SLC2A3,VEZT,TMEM199,TXN,MIR16-1,TUBB4B,NCK1,MIR423,TMED1,BET1,TNFAIP1,SERPINB1,ICAM3,LITAF,GALNT4,ACAT1,CD248,STK11,RAB2A,CPLX3,PRKACB,GSTK1,TLR6,VPS4B,MIR23A,NME2,MBLAC2,TF,BLOC1S5,TSSK1B,RHOG,TMED5,CORO1C,PPIB,HUWE1,MIR125A,SNX3,LPAR1,PIP4P2,TMEM95,AZIN2,OXSR1,TYROBP,IRF6,BICD2,AASDHPPT,FTH1,HBB,WWP1,GMDS,SNX33,SLC17A5,TNF,TIMP1,CLVS2,SST,CALU,MIR26B,VDAC1,HTR2A,TRAPPC4,AZGP1,LMAN1,TGFB2,AHSA1,YWHAB,ARRDC3,RAB22A,SCG5,GABRB2,ATP1A3,RNASET2,DENND6B,RAB23,ZDHHC17,MIR638,SIT1,FAS,RPLP0,PIP4P1,SLC30A5,MIR130A,CALR,CMBL,TSPAN15,CD1B,CFTR,CSE1L,MIR338,APPBP2,CUL3,SYNRG,SPP1,SPRED1,RRAS2,FAM3C,WWP2,MIR10B,SLC32A1,NRP1,PSMA1,CAMP,ALPL,DIO3,DIPK2A,PPIA,PSMD3,CYB5R1,TAB1,S100A8,TOM1L2,AP1M1,ST13,C9orf72,SNX18,CNIH4,CAPZA1,MGAT1,MIR198,RAB4A,PCSK2,BGLAP,RPS28,B4GALT3,GAL3ST4,FLOT1,KRT7,TSG101,TSPAN3,FABP4,GNA11,PSMB5,ZMPSTE24,MIRLET7C,H2BC14,PLEKHO2,COPZ2,GOLGA7,PLEKHJ1,SYNPR,RPLP2,FGFR1,NEO1,FCHSD2,CD38,TTR,SPPL3,MIR148A,MYL6,BMP1,NFKB1,HSPA8,MDH1,CSNK2B,MIR34A,SYNGR4,PSMB9,TMEM74,SPG21,GLIPR2,HNRNPC,NF2,ATP6AP2,RPL26L1,OPTN,SH3BGRL,SLC2A8,CAPZA2,GTPBP2,HINT1,SEMA4C,LAMP2,TXNDC17,CDKN1B,ATP1B1,SNX14,PPP1CB,PICALM,TRAPPC3,RND2,LAMP5,PRRC2A,PRDX6,ATP1A2,MGAT4A,SHMT1,UPK1A,CCT7,DEFB1,NPC1L1,VAMP5,CXCL1,KLK6,OGN,LYPLA2,TMED4,SOD3,SH3BP4,ENTPD4,FAM168B,NCSTN,SNX20,FKBP4,CCT5,B4GAT1,SLC15A2,EXOC3,COMMD9,ARCN1,RNF11,EHD1,CPNE2,GBE1,TICAM2,ACTR2,SVOP,DVL2,PRELP,DNAJC3,TP53INP1,PYGM,LPAR2,SERPINA3,PACSIN3,MIR29A,STAMBPL1,DPEP1,LUM,TRIM21,HDAC6,CD81,FZD4,BPIFB1,BTG2,SFRP1,GOLGA5,USP8,CAV2,MPST,COPS4,GSTA1,NAA16,GSTO2,MIR30E,OCEL1,GK2,STAMBP,ANXA4,VAMP2,AQP2,HERC3,CD36,PRSS12,GSTM3,MIR126,SLC12A2,PSME1,TRAPPC6B,MRC1,PDZK1IP1,SERPINB6,ZNHIT6,SNX22,REP15,THRAP3,PARM1,OPRK1,SNX2,SRI,PLA2G5,RAB6B,MIR24-1,GABARAP,THY1,RPS13,CPE,CCL28,LGALS3,BPIFA2,FAM234A,STX5,RNF148,MIR152,LAP3,CD58,HSPD1,HNRNPA1,STX10,PCNA,PRDX2,LY96,GNG2,SOD2,MIR17,CSK,RAB3D,MIR222,SNX17,FABP5,PCYOX1L,PLCB1,CFAP20,GNAI2,H2AC25,JAK1,TAGLN2,TOR1B,APEH,NCALD,CTNND1,MIR29C,CALML5,OR51E2,TUFM,RAB37,RPL26,CRYAB,ADAMTS1,MIR106B,PRRT1,ATP1B3,ABHD2,LMBRD1,VPS16,IZUMO1,GAD2,FCER1G,PDCD10,MIR92B,ACP2,AK2,OLFML3,C1GALT1C1,RAB29,GSTA2,LAMTOR2,TLR7,SNAP91,YWHAG,COPS5,MIR146A,TIRAP,SERPIND1,PLEKHF1,RAB8B,LILRA3,AFTPH,MAP2K1,REG1B,RPS2,RAB19,RPL4,GPT,TBC1D24,COL1A2,CTNNA1,CTSD,ALB,MARCHF3,VTA1,GNB4,RNF167,OVGP1,TMED3,CTSA,IL15RA,DPP4,EMP2,PSMB6,TRAPPC13,UBB,NECAP1,IFNAR1,ADRB1,CCT8,ARHGAP21,RNASE6,MTMR2,SLC1A2,GABRB3,ABHD17A,MIR185,SYBU,RPS27A,TAB2,TMEM106B,ABHD8,TM9SF1,GABBR1,SAMM50,EHBP1,HFE,HMOX2,DPEP3,CX3CR1,STX16,CHID1,WDR83,CHMP1B,SPTAN1,OLR1,B2M,RNF128,SEPTIN7,NEU1,MREG,SIAH2,RUVBL2,LDLRAD4,MIRLET7D,RAB1A,VIPAS39,VAC14,MBL2,MYO1B,AP3S2,CTTNBP2,TLR8,NECAP2,PGA4,PSENEN,ANKRD50,RHCG,GPM6A,PGM1,MYO6,IDH1,SYT2,HSP90AA1,CLBA1,TRAPPC1,TBC1D17,RPS11,GNG5,RALB,SELENOP,GSTT2B,PPIC,PTP4A2,LYZ,CD1D,RABAC1,WNT7A,OCRL,TBC1D5,CTSB,MARCKSL1,PDIA6,PRDX1,ACTA2,UGP2,TNFAIP3,CFL2,GNPDA1,H2AC6,STARD4,CAPG,LYZL4,CCDC22,HSPA13,AP2S1,SLC4A8,HCLS1,RAN,HEBP1,SYK,SFTPD,GRID1,MIR191,NAPA,MIR15A,TESK1,MYL12B,BAX,SPRED2,ATP6V1D,UBE2V2,TRIM3,HILPDA,TAX1BP1,ATP1A1,CSH1,ALDH1A3,CHMP2B,STX8,AP1AR,GPR89A,RPS5,KLK3,GANAB,AKR1A1,LAMTOR1,PEG10,NUDT9,PADI2,IL12A,TIMP3,GNPNAT1,SLC20A2,LAPTM4A,MIR30D,LGI3,PDCD5,ACSL4,SCAMP5,ARF1,GNB1,CCR5,APH1A,RALA,GPC4,RAB9A,SERPINB10,STX1A,YPEL5,UBE2N,AVPR1B,ARL15,MCOLN1,CHMP2A,TMEM123,SERPINA5,SFT2D2,CSTB,DYNC1I2,PGRMC1,HNRNPL,CAMK2G,GCHFR,PHB1,GPC1,RHOBTB1,TEX264,AGTRAP,FTL,NRSN2,H2AJ,ZNRF1,DDIT3,UBXN6,OPRM1,CD79B,NSG1,CNDP2,CD9,RAB14,MIR21,RPL28,DSTN,GLOD4,LAMTOR3,MSN,CAPN2,BET1L,GRIA1,MT3,EFNB1,HNMT,H1-1,VEGFA,GOSR2,COTL1,TOMM70,DNAJC7,MYL12A,ARL6,TP53INP2,SFTPA1,ANXA7,EEF2,SGIP1,TUBG1,SUB1,TNFSF10,BLVRA,RAB40AL,CARTPT,PLA2G15,PRDX4,H2AZ1,SPTBN1,CD274,AP1S2,WDR44,LDLR,PSMD14,RPL35A,TLR2,IL2RB,RAB3B,SMURF1,ICA1,F9,PCBD1,XPNPEP1,SELL,TRAF3IP2,TUBA1A,SYPL1,ROGDI,CHP1,CLRN1,BOK,GFUS,VMO1,GSTO1,YKT6,LYZL6,MIRLET7I,GHRL,MIR214,RPE,VAMP1,MIR223,TMEM108,USE1,LHFPL2,PRL,HSPB1,PITHD1,SYNDIG1,HP,GNA14,MDM2,NIPA2,RPL23,MLC1,FGR,SIAE,WASL,CPTP,RBP5,MIR30B,IL18BP,RARRES2,SLC6A4,PSMB2,PACRG,H2BC9,PDLIM4,HSPA5,DNAJC5,XRCC5,SDCBP,RHOU,GSTT1,ATP6V1G2,PGK1,FURIN,HSP90AB1,CAND1,TREML1,MIR145,CLCN6,BRI3,DNM2,NRBF2,SEMA5A,RAB31,TOR4A,ACTB,ARF6,MIR671,GABRA1,SLPI,RPL22,GOSR1,TMEM30A,HTRA1,GZMK,TAX1BP3,PLCB2,MYD88,GDI2,KLK9,RGS19,SLC22A6,H2AC1,SYNGR1,SLC35F1,HPS6,STXBP1,PSMA4,MACROH2A1,PLA2G4B,ALDH1L1,RACGAP1,SEPTIN6,SEMG2,RAB13,SCAMP2,FSTL1,CRTC2,CRYL1,MAT2B,MMP9,KIF3B,VAMP8,GNAQ,RPS14,SNRPD2,STOM,UBE2D3,ADSS2,PRSS8,TMED9,PITPNA,ACTR3B,YIF1A,GSTCD,CAV3,SAYSD1,APOC2,INPP4A,GPNMB,STK16,SOD1,SLC18B1,VPS33A,GLO1,RHEB,JCHAIN,PEBP4,PDYN,KRT8,TMBIM1,TNFSF13,ACKR3,CACYBP,RPS9,CKB,MIR101-1,MAP1LC3B,BECN1,NME1,BORCS5,CYFIP2,CMTM6,VAMP3,SSBP1,TLR1,CLIC4,PRCP,ACTL9,ENO2,CD63,CLCA1,EXOC8,LILRB4,FBP1,CNP,PPT1,COMMD3,LEPROTL1,TMEM256,SAR1B,AP5S1,S100A11,CHMP5,CTLA4,SV2B,CTSK,YIPF5,SLC25A3,AKR1B1,KDELR2,EIF3E,FZD6,AKR7A2,NAA50,RAP2A,SVIP,RAB3C,RPS29,MIR194-1,GPX3,TBC1D16,PSMD6,CDK1,MTAP,PPP2R1A,SEMA3C,HAX1,HBEGF,PROM1,TMSB4X,YIPF3,TBC1D4,PLAA,DDAH2,NECTIN2,HMGB1,SYT4,EIF4E,RHOB,GNPTG,MIR192,F2,CRHR1,CXCL12,TPT1,EIF2S1,NUDT1,ROCK1,PAK2,MAP1LC3A,CD3G,PI15,MME,TMED7,STARD3NL,BPGM,NDFIP1,SNX1,SNX12,TMX3,CHI3L1,UBAP1,MBD5,SURF4,SIGLEC5,YWHAH,RNASE1,PGAM1,EPCAM,DDR1,TMEM45B,RPS20,DNPH1,LCP1,H3C1,MIR99A,DDT,VPS26C,H2AC13,STAU1,TOM1,SLA2,RAC2,CTSC,AOX1,RPL23A,PMP2,MIR100,VPS4A,ARHGAP1,GPX4,VPS39,PPFIA2,IFT172,FCGR1A,LAMP3,PATE4,ESD,AP2M1,FCMR,IRF7,VEGFC,IQSEC1,GDE1,CDC37L1,SNAPIN,CTNNB1,TXNRD1,ATG9A,SNAP23,MIR1234,VPS26A,H2AC7,SNX24,SLC31A1,RPSA,ATP6V1C1,PSMB1,GNG12,CALY,F7,TMEM33,TAPBP,CEACAM5,FLRT2,HEXB,BST2,AQP4,FAF2,GCNT3,SCG3,MIF,TMEM168,RHOJ,FAH,MTM1,RPL37A,TRIM27,GNB3,HYAL2,ADGRG1,SLC66A2,RAB5A,CCT2,RUSC2,VPS26B,LRP6,CYBRD1,AMELX,HIRA,PSMC3,FBP2,FCN2,MIR20A,SLC1A3,HSD17B6,TMEM190,RPS26,PYCARD,CDH13,GGCT,ABCB1,GLIPR1,PAFAH1B2,SRP14,DBH,PICK1,PDIA3,TRAF6,NDUFC2,TGFB3,RPN1,GDPD3,DERL1,FGL2,GAPDH,ANGPT1,ANGPTL2,RPL27,LGALS8,SRSF7,IDE,ILF2,SNX10,CHMP4C,TFRC,ITGB5,PBLD,PTGDS,TRAF7,PSME2,KLK5,HBA1,EPS8,TCP1,MOXD1,CLVS1,CAB39,REEP6,PABPC1,NEDD8,MIR619,MIR215,PRNP,GABARAPL1,FUT8,EEF1A1,NPC2,SYNGR3,COMT,RAB11A,RUVBL1,TUBB,IGF1,TRIM36,TMEM179B,OLA1,CACNG3,NPY,PSMD1,GMPPA,RPS4X,S100A6,RAB32,SCPEP1,RAB11B,PSMA2,DUSP26,ATP5F1A,STK26,TMT1A,PRDX3,RAB6A,CIDEB,LDHB,GABRG2,DERL2,AIF1L,ARPC3,SLC16A1,RPL3,PAFAH1B1,VAMP7,MIR106A,ARPC2,ASTN1,PNP,SFN,CYB561D2,FAM91A1,PEBP1,GCA,CSRP1,CEND1,HEBP2,TNFAIP6,USP14,BACE1,PML,IRAK4,MIR208A,PSMB4,AKR1C1,TMUB1,RAP1B,TOR3A,STBD1,TBC1D25,HAS3,NCKAP1,PSEN2,USP6NL,SPRN,PALS2,GSTP1 |
| 9.708e-14 | -29.96 | TMPO (thymopoietin) | protein interactions | 7112 | 733 | 297 | 19454 | 5460 |
TOR1AIP2,PGRMC1,NOTCH2,OTULINL,RND2,VAPB,EMC9,SLC25A3,TXNL1,HADHA,JADE1,STX7,PXMP2,VEZT,HNF1B,ACO2,RAB11A,CUL3,MCM3,MYO6,LMNB1,SCFD1,HSP90AA1,ARF1,SNRPD2,SEC61B,RPS9,MB21D2,EIF4A2,ACTB,LGALS3,RPL35,MACO1,B3GNT2,RAF1,GFPT1,FAF2,ERLIN2,RPN1,STIM1,CHMP4C,RPS11,SSBP3,HSPD1,TMT1A,SRSF7,EMC8,ARL5B,SRSF4,RAD21,RETREG1,SAR1B,PRDX1,ATG9A,HNRNPA1,RHOG,CDK5RAP3,RB1CC1,AHSA1,C2CD2L,RPL9,RPL8,ARL11,PHB1,RPLP2,HP1BP3,CCAR2,RPL7,SPTAN1,EGLN3,ERLIN1,NUP35,DHX15,RABL3,ARHGAP1,SEC22B,CCND1,ST7,CDK7,CDK1,LMNA,TMX4,METTL14,STOM,GOLGA5,PDCL,RARS1,RPA3,FADS2,CLK1,ARPC2,SQSTM1,RTN4,MTDH,YKT6,NF2,RPL4,FBXW7,DAD1,TMEM209,CIAO1,USP14,PPP1CC,HMOX2,AP2A1,CCNF,EIF4A3,RTRAF,GANAB,TMOD3,ZNF622,RHOJ,SEC63,VIRMA,FBP1,CCDC47,CCT5,LBR,UBR7,EXOSC8,CAMK1,ACTR2,ILF2,FAM169A,NSDHL,SLC25A10,RPL23A,PC,HUWE1,FARSA,SGMS2,EIF3E,RIGI,SMN1,TMEM199,EMC4,SLC25A46,GMPPA,LAMP3,HDAC6,POR,ESYT1,OSBPL8,BRD3,SRPRA,PTPN1,RPL12,HSD17B11,CDCA3,RB1,ARF6,CDK9,ZBTB2,SLC25A12,SEC62,NEK7,SDC2,MAP2K1,CSNK1A1,XRCC5,FAM50B,SF3B1,HSPA8,DDX5,EP300,PCGF2,RAB5A,UFL1,PHB2,MYC,OST4,HNRNPC,PAPOLA,BTF3,CIRBP,CCT2,ICAM1,SERPINH1,LMBR1L,IRF2,DLST,BST2,ATP5F1B,MATR3,FBXO22,ATP6AP2,RPL10,KBTBD6,ESR2,STBD1,ISG15,SOX2,DNAJC25,PDHA1,RAB4A,HDAC11,RND3,MOB3C,RPS23,CCT8,PABPC1,RINT1,MYO1B,RUVBL2,RTCB,KRAS,HNRNPF,RUVBL1,NUP42,RPS4X,LAMP2,RPL6,RAB5C,PPIB,DDRGK1,CTNNB1,CBL,DDX1,SRSF1,EED,STX5,HNRNPL,RHOH,SUMO2,TCP1,PEG10,CDC42,H2BC11,RPA2,USE1,SSR1,SAMM50,LEMD3,RPL27,BAP1,DDX46,TEX264,UGDH,BANF1,PML,RAB9A,DERL1,RNF113A,RPS15,HDAC3,OIP5,CLU,HSPA5,MARS1,SLC25A1,SUB1,RPL7A,CFL1,RPS17,TLR9,ATP1A1,IGF2BP1,UBE2H,ATL1,LIG3,SRP54,CSNK2B,SGTA,SMURF1,SRC,SRPK2,PREB,NUPR1,SLC25A11,STX18,ABCE1,RPL3,IDH1,DHX9,NUP107,CHMP1B,H3C1,HNRNPK,FKBP8,ENY2,FAM20C,CD81,CSNK2A1,TPM3,TUBG1,RPL24,RPS2,AKAP8L,RPL10A,COQ8A,CAMLG,RAC2,FZR1,DNAJC1,CAND1,LMAN1,CDC5L |
| 1.001e-13 | -29.93 | TOP2A (DNA topoisomerase II alpha) | protein interactions | 7153 | 481 | 210 | 19454 | 5460 |
ELOC,COPS5,CSNK2A1,RPL24,H2AC4,CHCHD1,SNRNP70,MED27,USP15,RPL10A,KPNA1,RPS2,RPS27L,RPS16,CDC5L,MBD5,TP53,NECAP1,CBX3,NUPR1,CAPN2,HBP1,ZNF451,DHX9,RPL3,ABCE1,H3C1,FKBP8,RPL17,RPS17,H2BC9,UBE2H,IGF2BP1,ZBTB38,ZNF330,PSMA6,RPS3,MACROH2A1,CSNK2B,EIF2S2,PSMC5,SRP54,SRPK2,SMURF1,SUMO1,CFTR,RPA2,PRKCA,PML,NLE1,POLD2,BANF1,RPL27,RPL6,WWP2,IFI16,BAZ1B,CTNNB1,DDRGK1,XPO1,NCK1,DRG1,MAGOH,SRSF1,WDR82,EED,SUMO2,SNRPD3,RPS10,RPS7,ISG15,SEC61G,GLE1,RPL18,MTA2,TOP2B,RPL31,RUVBL2,VDAC1,PSMA2,KRAS,PRPS1,TFG,RPS4X,RPL28,HNRNPC,MYC,BTF3,PSMD14,DLST,SF3B4,SNRNP40,RPL10,PAFAH1B1,PSMB3,RPL27A,RPS28,XRCC5,SNRPA,EP300,THBS3,HSPA8,SF3B1,STAU1,SSR3,FXR2,SRSF2,TRIM52,H2AC14,ZMYND11,BRD3,FOXP1,RCHY1,H2AZ1,RB1,TOP1,CWC15,ZBTB2,POLE3,FBP1,RPL15,LLPH,SRP72,ILF2,VAC14,RING1,VRK1,H2AC6,PTGES3,CIAO1,CDC73,TNFRSF1B,CCNF,TRIM24,RPS20,UBE2I,RPS12,NDN,VIRMA,RPL22,UBA52,ATG16L1,PSMC4,RPS14,CDK7,GRM2,METTL14,LMNA,CDK1,PAK5,MACROH2A2,SIRT7,PRIM2,RPA3,MTDH,PRKCB,FBXW7,RPL4,HMGB1,NUCKS1,HMGA1,PRPF19,DDX23,RPL23,AHSA1,FBXO32,PSMB5,RPL8,RPL9,RPLP1,HP1BP3,RPLP2,RPL7,SRSF10,E2F4,FEN1,ZNF263,JUN,CHMP4C,EZH2,RPS11,NEK9,RPS24,PCNA,DHX16,G3BP1,SSRP1,CUL2,RPS29,DCAF4,BRCA1,MYO6,MED10,RIT1,RPS5,FAU,RPS9,SNRPD2,SNRPD1,RBBP4,RPL35,RPL19,UPF3B,FOXD3,G3BP2,ASB3,FTL,COIL,POLA2,PSMC1 |
| 1.113e-13 | -29.83 | CCDC47 (coiled-coil domain containing 47) | protein interactions | 57003 | 428 | 191 | 19454 | 5460 |
ATP6AP2,ESR2,APLNR,TOM1L1,LMBR1L,PSMD14,FIS1,OST4,MYC,TMEM38B,PHB2,STAU1,RER1,SSR3,RNF5,UFL1,EMC1,TMEM106B,JAGN1,MIA2,AKAP1,RAB5A,FDFT1,CCDC167,SEC62,TIRAP,RHOH,RAB1B,COX14,RAB35,FAM241B,DRG1,SEC61A2,RAB5C,LAMP2,DDRGK1,KRAS,RPL31,CYP2C9,SEC11A,SEC61G,RAB4A,PTRH2,RND3,MSX2,DNAJC25,PSPC1,SEC61A1,CYBC1,ATP1B3,SPOP,CALU,UBE2H,ATP1A1,RPL7A,RAB2A,TIA1,BVES,IRF3,TEX264,TMX2,DERL1,RAB9A,SSR1,RPA2,CDC42,TRAM1,DNAJC1,ARL6IP5,RPS16,TMED9,SLC38A2,STX6,TMPO,LMAN1,UBE2G2,COMT,STT3A,RAC2,NUS1,EDEM1,FAM20C,DPP4,COPS5,SRPRB,TGFBR2,RAB3B,TMEM33,RDH11,FKBP8,CYBRD1,STX18,TFRC,PREB,MGARP,SPCS1,PIGK,SARM1,SEC61B,RMDN3,LMNB1,ILK,CNIH4,NTRK3,RAB11A,PYCR1,CUL3,DNAJC22,STX7,PXMP2,EMC9,VAPB,PGRMC1,RND2,OTULINL,TMEM237,EGLN3,ERLIN1,PHB1,CYB5A,GJA1,RHOG,CDK5RAP3,RB1CC1,RNF139,FAM174A,MARCHF5,EMC6,EMC8,SACM1L,TMT1A,GPAA1,TMEM147,RPN1,STIM1,CYB5B,EMC10,MACO1,DCAKD,RAF1,ERLIN2,SEC63,WDR83OS,TECR,SELENOT,CCNF,PTEN,ODR4,DNAJC19,CIAO1,RETSAT,HMOX2,FBXW7,IRF7,TMUB1,DAD1,RPA3,SPCS2,SYVN1,TMX4,SLC12A2,MANBAL,TIMM23,LMNA,SEC22B,ATG16L1,ST7,DERL2,PRNP,ARF6,MSMO1,SRPRA,PTPN1,HSD17B11,ESYT1,SLC2A1,POR,SLC25A46,EMC4,TMEM199,EI24,LAMP3,DNAJC30,ELOVL7,TUSC3,RAB1A,IGF1R,EMC2,TMX3,MAP1LC3B,LBR |
| 1.175e-13 | -29.77 | PSMA4 (proteasome 20S subunit alpha 4) | protein interactions | 5685 | 289 | 140 | 19454 | 5460 |
E2F4,TXNRD1,ARFGEF1,RAF1,B3GNT2,SOX2,ISG15,CHMP4C,EZH2,MOB3C,HNRNPA2B1,CCT8,UBE3A,EWSR1,PSMA2,HNRNPF,PSMA1,KRAS,PSMD12,RPS27A,BABAM1,IFI16,PSMD3,GSTM3,WDR11,DDRGK1,PPIB,PSMD10,AGR2,ELP6,PHB1,PSMB4,PPP2CB,PSMB5,PSME2,CCAR2,TCP1,DHX15,CCT7,NUP35,CACYBP,EGLN3,PSMB3,PRDX3,PSMB7,PIH1D1,CNDP2,ARCN1,HERC3,PSMA3,HSPA8,UFL1,SELENOO,SKP1,PSMC1,DDI1,PSMA4,MYC,PSMD1,PSMD14,POMP,RIT1,NFKBIA,RAN,PSMD6,PSMD4,PSMB6,INSIG2,CCT5,EEF1A1,PSMB9,ACTR2,TFCP2,RAD23B,PSMC3,PSME1,MAP1B,PPP1R12A,TGFBR2,TOLLIP,SEM1,NEDD8,HUWE1,PSMA5,FKBP8,MEPCE,PSEN1,NFKB1,CSNK2A1,PSMD7,PSMG2,MAP4,CD274,MRPS9,PTPN1,PSMB1,FZR1,G6PD,PSMC4,ATG16L1,CFTR,PAAF1,CDK7,GRM2,METTL14,RPA2,HEXIM1,TFIP11,UBE2M,RPA3,RHOU,BAP1,EXOSC4,PSMG4,FBXW7,DESI1,GTF2I,MARS1,EIF4E,PTPN11,PSMB2,MAT2A,USP14,FBXO7,PSMG3,UBE2H,ATP1A1,XPOT,CTNNA1,PSMA6,CCNF,STUB1,MSN,GANAB,PSMC5,ADRM1,CHMP5,VIRMA,UBB,SMURF1 |
| 1.198e-13 | -29.75 | METTL17 (methyltransferase like 17) | protein interactions | 64745 | 406 | 183 | 19454 | 5460 |
GRSF1,KRR1,PRR3,MRPL50,TOP1,CDK9,ATP5PD,DBT,MRPL24,MRPS23,MRPL11,NDUFA2,PPIF,BCS1L,NDUFS3,MRPL51,MRPL49,PPP1R12A,RPL23A,EMC2,HSD17B10,HSPE1,RPS13,FASTKD5,MRPL22,MRPS18C,MDC1,AAMDC,PYCR2,NONO,MRPL53,CCNF,CTTN,FBLN5,ACAT1,TOX4,MRPS34,ZNF574,MRPL17,PDHB,NF2,MRPL20,POLDIP2,CRYZ,CLPX,STOML2,MRPS35,NDC80,MMUT,ATG7,MRPL18,MRPS26,HNRNPD,RPL8,PHB1,NDUFS8,NUF2,HSDL2,RAF1,RPL29,JUN,EZH2,NDUFS6,OSTM1,PREPL,HSPD1,ARGLU1,THNSL1,HINT2,FAM76B,MRPS11,ETFA,ATP5F1D,MRPS17,MRM2,PMPCA,PYCR1,MRPL16,NOA1,PNMA1,MRPL23,NDUFAF4,RPL19,PRDX3,PPP1CB,ATP5PO,MFAP1,NDUFA5,ATP5IF1,HADHA,HSCB,MRPL57,PSMC1,G3BP2,RBFOX3,COX5A,PPIL4,SNRNP70,TRMT5,SDHB,SYNCRIP,MRPS9,ALYREF,COX4I1,MGME1,MALSU1,ATP5PB,MRPL47,RPSA,HADH,DDX42,TAF2,MRPL52,ATP5PF,MRPS18B,MRPS33,PDE12,HNRNPK,PHYKPL,PHF1,MEPCE,NDUFAF2,CEP70,MRPS16,MECP2,OAT,IGF2BP1,PSPC1,MRPS28,MRPS21,PPP1R10,TRAF1,NDUFAB1,MRPL10,QRSL1,TFIP11,HEXIM1,TWNK,GFM1,DLAT,NME4,MRPL40,MRPL41,GRPEL1,CLU,MDFI,MRPL9,NDUFV2,FOSL2,WDR82,FAHD1,HNRNPL,RPS10,PNPLA8,SPC24,ETFB,H1-3,PDHA1,NDUFA12,RPL31,KGD4,HNRNPDL,HNRNPAB,MRPS25,H1-1,MCAT,TACO1,ATXN1L,DLST,SF3B4,MRPL13,ATP5F1B,FBXO22,APEX1,RPL10,MRPL12,NDUFAF3,MRPS18A,NUFIP2,NGRN,NDUFS2,PHB2,MRPS7 |
| 1.206e-13 | -29.75 | CUL5 (cullin 5) | protein interactions | 8065 | 533 | 228 | 19454 | 5460 |
PRDX3,TOR1AIP2,ASB8,H1-5,ANXA7,RNF7,FEM1A,APOBEC3C,PMAIP1,CCDC184,RAB40AL,UPF3B,SKP1,ASB3,SOCS5,SAMHD1,CUL2,CUL3,ILK,RPS5,SCFD1,HSP90AA1,LRRC28,RPS9,SNRPD1,SNRPD2,DIO2,APOBEC3G,SNRPB2,RPL19,MAT2B,ACTB,RPL35,TUBB,DCUN1D3,JUN,TPD52,SNRPE,POLR2D,POLR2C,EZH2,SRSF7,RPS24,PCNA,SLC39A7,HNRNPA2B1,SLC25A5,COPS4,FEM1B,TRA2A,CISH,HNRNPA1,PTPN5,PRDX1,DCAF11,HNRNPD,AHSA1,TRAF6,RPLP2,COPS2,RPLP1,HP1BP3,CBFB,RPL8,DHX15,RPL7,COPS7B,RPS14,RPLP0,RPL26L1,HNRNPH3,UBE2F,HSP90B1,RHOU,RPA3,MBD3,RPL4,DNAJC8,TUFM,ATP5F1A,SEC13,CSK,CTSD,XPOT,SMAD2,EPHA2,RPS20,TRIM27,RTRAF,METAP2,ENO1,CCNF,RPL22,UBE2L3,RPL13A,TXN,LDHA,SOX9,RPL15,SOCS3,EEF1A1,ILF2,SPSB3,HSD17B10,KLHL15,RPL23A,SPSB1,RIGI,SNRPG,SOCS2,RPS13,ANAPC11,H2AC14,MOV10,NFKB1,GRSF1,SOCS4,AIFM1,RPL12,G6PD,POLR2I,PRNP,DCUN1D1,ASB11,NUP62,RPL27A,PAK2,CTBP1,DDX5,EP300,HSPA8,RPS28,SNRPA,SRSF2,HNRNPA0,TRA2B,SNRPB,SLC30A5,HNRNPC,HNRNPAB,CREBBP,COPS7A,CIRBP,COMMD9,CKB,POLR2B,PCMTD1,RPS7,EEF2,TRAF2,ETFB,DCUN1D5,RPL18,RHOBTB1,GHR,TUBB4B,PLS3,PDIA6,RTCB,EWSR1,TOP2B,PABPC1,RBM3,RPL31,RWDD4,HNRNPDL,TFG,DCTPP1,RPS4X,FEM1C,HNRNPF,STK4,RPL6,ASB1,INPP4A,ASB7,DDX1,FKBP4,HSP90AB1,SNRPD3,HNRNPL,RAB1B,RPS10,FAM98A,WSB1,CAPN1,UBE2M,RPA2,HNRNPH2,RPL27,HSPA5,H2AC13,PCBD1,TIA1,NUDT1,SMARCA5,IGF2BP1,DNAJC10,RCBTB1,RNF187,RPS3,CREB1,UBA3,SMURF1,PCMTD2,DHX9,ERO1A,RPL3,NOSIP,TNKS2,HNRNPK,NEDD8,PDE12,ELOC,COPS5,RPL10A,RPS2,H2AC4,NXT2,SNRNP70,RPL24,PREP,SYNCRIP,EEF1B2,SSBP1,NKAP,CAND1,RPS16 |
| 1.233e-13 | -29.72 | YKT6 (YKT6 v-SNARE homolog) | protein interactions | 10652 | 229 | 117 | 19454 | 5460 |
PEBP1,EXD2,HSPA8,AKAP1,BET1L,RAB5A,GOSR1,HSCB,GPM6A,PHB2,PXMP2,STX7,PTAR1,CLDN4,MTX2,BET1,RND2,OTULINL,SEC62,FKBP1A,RMDN3,SEC61B,TAGLN2,RAB11A,BAG3,LAMTOR1,LMNB1,RHOB,SCFD1,NTRK3,FIS1,RIT1,CYP2C9,TMT1A,RABGGTB,COX8A,KRAS,ETFA,FLOT1,DNAJC25,STIM1,EZH2,RPN1,RAB4A,RND3,STX12,RAB35,GJA1,STX5,RHOH,DIRAS3,COX14,LAMP2,CRIP1,ATG9A,HMGA1,MARCHF5,RAB5C,RHOG,HAX1,CDKN1B,PEX3,RPA3,RHOU,MAVS,RAB9A,DERL1,NAPG,TOMM20,CRYZ,SPR,CDC42,ST7,LMNA,RPA2,USE1,SSR1,FGFR1,CTNNA1,RHOJ,SEC63,RAB2A,VAMP5,ARL6IP6,DNAJC5,NAPA,STX8,C1QL1,IGF1R,TAGLN3,RAB3B,STX11,FKBP8,MPST,RIGI,SNAP29,MTCH2,CENPM,UBE2V1,FNTB,TFRC,PTPN1,HRAS,ARL10,HSD17B11,RAC2,DNAJC1,ARF6,MIF,LMAN1,TMPO,STX6,CAV1,SLC25A46,LAMP3,ESYT1,CNN3 |
| 1.241e-13 | -29.72 | mitochondrial protein-containing complex | cellular component | GO:0098798 | 273 | 137 | 19108 | 5553 |
MPC1,TOMM6,TIMM8A,HADHA,TIMM17A,MRPS16,UQCRC1,ATP5F1A,MRPL20,COX5A,MRPL52,ROMO1,MPV17L2,MRPL47,MRPS17,NDUFA2,MRPL33,MRPS7,COX4I2,CLPX,DNAJC19,COX6C,MRPS18C,MRPL50,TRMT10B,PPIF,MRPL40,MRPL18,TOMM70,NDUFA12,ATP5MK,BAX,MRPS18A,IMMP2L,CHCHD1,SMDT1,SDHB,NDUFS3,COX6B1,NDUFAB1,TIMM21,SDHC,PHB1,MRPS35,NDUFS8,MRPL10,TIMM8B,ATP5F1B,NDUFS6,TOMM7,UQCR11,GRPEL1,UQCC3,NDUFB4,CYC1,NDUFV2,MRPL36,MTX2,MRPL12,MRPL17,TIMM10,NDUFA1,SLC25A4,MRPL49,TIMM13,ATP5F1E,APOO,ATP5F1D,NDUFB5,MRPL53,AURKAIP1,MRPS34,UQCRC2,CHCHD6,TOMM20,ATP5PO,NDUFB8,AGK,MRPS21,GRPEL2,MRPL11,TOMM40,MRPL41,ATP5PD,NDUFB7,VDAC1,UQCRH,PDSS2,HSD17B10,MRPL24,MRPL51,UQCRQ,MRPS9,ATP5MC1,MRPL57,MRPS18B,CHCHD3,TOMM22,TOMM40L,MRPL22,TIMM29,MFN1,ISCU,COX7A1,ATP5MG,MRPL13,TIMM23,ATP5MC3,SLC25A5,SAMM50,ATP5PB,MRPS11,FXN,NDUFA4,NDUFS2,PHB2,MRPS26,MRPL16,NDUFB10,ATP5PF,PMPCA,MRPS23,MRPS33,MRPL23,NDUFC2,COX8A,MRPL34,MRPS28,MRPL9,SLC25A31,COX7B,NDUFA5,COX4I1,MRPS25,NDUFB6,COX6A2,BCS1L |
| 1.242e-13 | -29.72 | FAU (FAU ubiquitin like and ribosomal protein S30 fusion) | protein interactions | 2197 | 191 | 102 | 19454 | 5460 |
RPSA,TP53,RPL23A,MRPL22,RPS13,MEPCE,VRK1,COPS5,CD81,HDAC6,ZMYND11,MICB,RPS2,BRD3,ESYT1,SNRNP70,H2AZ1,RPL12,MRPS9,ALYREF,RPL32,DKC1,ZBTB2,FZR1,CAND1,RPS16,RPS27L,KLF12,CFTR,ATG16L1,TPT1,KLF4,RPA2,WWP1,RNF113A,BAP1,RPA3,PNO1,PRPF4,HSPA5,RPS15,RPS17,PPP1CC,MAPRE1,UBE2H,RC3H2,EIF2S2,RPS12,RPS20,PSPC1,RPS3,CCNF,METAP2,NDN,OTUD6B,MSX2,RPS7,B3GNT2,E2F4,RPS11,RPL18,RPS23,EZH2,CHMP4C,RPS24,RPS4X,SSRP1,G3BP1,H1-6,KRAS,TRIM37,GNL1,ATG7,MRPL9,DDRGK1,TAF7,WWP2,AHSA1,DRG1,SPTAN1,RPL27A,PAFAH1B1,KLF3,PYM1,RPS28,MRPS7,G3BP2,RPS29,MYC,CUL3,ICAM1,RPS26,ELAVL4,H1-1,RIT1,ATG3,ZCRB1,BRCA1,SEC61B,RPS9,IRF2,DYNLL1 |
| 1.251e-13 | -29.71 | PRNP (prion protein (Kanno blood group)) | protein interactions | 5621 | 1118 | 424 | 19454 | 5460 |
DLAT,SNX33,ZBED3,PPP1R26,TXNDC17,NLE1,RPL27,CLU,NME4,AGO1,SLC4A10,CD2AP,KLF4,LEMD3,CALML5,CSNK2B,UBA3,TXNDC12,EIF4H,FBXO44,NPTX1,NIF3L1,MECP2,ZNF451,MAP1B,PHF1,ATP1A2,PSMA5,AKAP12,NEDD8,ESS2,RPSA,TP53,NUPR1,SGIP1,CAPZA2,PCMTD2,MTAP,CYTL1,ALYREF,IER3,ITGA6,SSBP1,MBD5,PLG,TPM3,ELOC,EDC3,COX5A,MAP4,SHC1,NR4A2,GPHN,PACSIN3,CHRNA7,SERPINB6,ADRB2,EEF1G,TRA2B,UFL1,TOM1L2,PSMB3,EIF4B,LXN,DLG4,SURF2,MOG,SCNM1,MTG1,DLST,RPL10,ESR2,LRIF1,HDDC2,STAT1,MATR3,PTPRZ1,SLC1A3,TBC1D1,PSMD1,BTF3,LDHB,PRMT6,HNRNPC,MYC,COX6B1,CIRBP,CCT2,KIAA1191,TFG,SLC35A2,XPNPEP1,EEF2,NCSTN,NUDCD3,HGS,TAF10,RPS23,CCR1,AASDHPPT,ECHDC1,ZNF740,NOB1,XPO1,AQP4,CBL,ZKSCAN1,IDH3A,INPPL1,CXXC1,TTR,RTL4,ST7,UQCRC1,PCK2,COQ8B,WTAP,CARHSP1,HNRNPH3,MMADHC,PICALM,CZIB,STOM,ASPA,RPS12,CTTN,ENO1,PDCD5,JUNB,TMOD3,COL1A2,AP2A1,SYP,IGF1R,NSMCE3,ZSCAN5A,ERLEC1,FNTB,MMACHC,LDLR,KRR1,HRAS,HDHD3,SMAD3,CWC15,TNR,ELAPOR2,CGAS,ATP1B1,DAG1,GRSF1,POR,PSMA3,TXNL1,TBC1D24,DNAJC3,PYGB,CCDC186,SRM,ASRGL1,ACTL6A,ANXA7,IRF2BPL,CRYAB,SNRPD1,SNRPD2,VPS72,TRMT6,CLIC4,ABHD12,MAT2B,EIF4A2,PRDX2,RPS29,JPT1,ILK,SETD7,RPS5,CCDC25,HSP90AA1,OMG,RHOB,ARHGAP19,PLCB1,HINT2,HNRNPA2B1,HSPD1,NUDT5,COPS4,FLOT1,PSMD12,ATP5F1D,PPP2R1A,ACTN4,GABARAPL1,DLG3,SNRPE,STX12,RAB6B,NDUFS6,BRD9,ATP6V1A,PSMB5,RPL9,TMEM237,AFAP1L2,ZNF207,PDAP1,HAX1,PPM1B,WDR12,CDK5RAP3,SKIC8,NR1I3,APMAP,HSPA5,RBM22,UBE2K,FGF13,XBP1,GTF3C4,SERPINI1,IDH2,SGTA,EIF2S2,PSMA6,GCFC2,UBN1,PAFAH1B3,DUSP3,PPP1R10,ROCK1,BUB3,GPX1,RALA,PCBD1,CHPF,RPS17,PTPN11,MAT2A,ATP1A1,EIF3G,SNTA1,ERO1A,NAE1,RUSF1,CAPZA1,TOLLIP,L1CAM,ARHGAP12,RPAP2,ACTR1A,IPO8,PSMC3,PHC1,TAF2,TAB2,NEFL,RBM34,TFCP2,COMT,CD99L2,IAH1,LRRC14,B9D1,CSNK2A1,DNAJB2,TMOD2,USP15,TUBG1,SMAD4,NAIF1,XRCC5,SNRPA,PYM1,PITHD1,ZNF362,RPL27A,NUP62,PALS2,ADSS2,ZNHIT6,EFHD2,FRZB,PSMD6,PSMD4,ISCA2,EPS8,NSA2,THTPA,ICA1,ICAM1,ACTR1B,CCT8,PABPC1,NDUFB5,POLDIP3,ARHGAP15,CRKL,METTL21A,STARD5,FABP5,PAIP1,PPFIBP1,PPIB,RIOX2,TAX1BP3,SYNJ2BP,HSPB1,FKBP4,DCAF5,MME,NHP2,NUCKS1,HMGB1,CNP,RBMS2,TPT1,LPXN,PSMC4,TMOD1,RPLP0,HSP90B1,LMNA,RPS20,TRIM24,GANAB,FBLN5,QNG1,DNPH1,DDAH2,HOMER1,LDHA,ATP5F1A,FXN,NCKIPSD,HINT1,TMX3,DLG1,ZNF787,RNF20,TOM1,CAMK2G,RPL15,MLLT6,NECAP2,LBR,CCDC47,SERPINB9,IRGQ,RAD23B,APEH,SRP14,CTDSPL2,DFFA,CAV1,MAPRE2,EIF2B5,PRNP,MPG,ZMYND11,HDAC6,ISYNA1,FOXC2,CALR,NFKB1,DNAJC7,FBXO34,SSX2IP,PSMD7,RLIM,TTC1,RNF10,NUP50,PSMC1,NSFL1C,GPM6A,NPTN,CNTN1,RPE,PRDX3,EHD1,FABP7,MYL6,CPLX2,AGGF1,RMDN3,PARP2,CYB5R3,ARF1,TSN,UMPS,OTUD7B,ZNF668,CUL3,CLBA1,ALDH1L1,BLVRA,ATP1A3,JAK1,MEF2C,CPLX1,GCA,LAMB2,LASP1,FEN1,TPD52,CPE,PLD3,STIM1,TSG101,GJA1,MYEF2,TRIM15,KIF3B,MRPS35,SAV1,HEBP2,PPP3CA,CDKN1B,RASSF8,AHSA1,TRAF6,CSTA |
| 1.263e-13 | -29.70 | TOP1 (DNA topoisomerase I) | protein interactions | 7150 | 649 | 268 | 19454 | 5460 |
INTS12,MACROH2A1,FGFBP1,ZNF330,LIG3,SF3B6,PSPC1,SRPK2,CSTF3,PPP1R10,PYGM,BUB3,PRKACB,CCNB1,SUB1,TRIM32,SMARCA5,UBE2H,IGF2BP1,CHRAC1,LSM6,MECP2,POLD2,BANF1,BAP1,RBM22,CFTR,GTF3C4,SUMO1,PPP1R8,HEXIM1,ZNF326,RPA2,RPRD1B,ALYREF,CD274,SYNCRIP,CDC5L,CAND1,FZR1,PPIL4,CSNK2A1,COPS5,SNRNP70,POLB,DHX9,MEPCE,HNRNPK,CDC40,H3C1,RPSA,TP53,CDK4,TAF2,NUPR1,IK,DISC1,DDX42,CHAMP1,CBX3,CDK8,DLST,CMTR1,POLR2B,TAX1BP1,SNRNP40,MATR3,CPSF2,BTF3,HNRNPAB,HNRNPC,MYC,RCL1,RPS26,PSMD14,H1-10,CHTOP,DDX5,SF3B1,HDAC5,XRCC5,DDX39B,SNRPA,RFC4,SAP18,STAU1,UFL1,TRA2B,HNRNPA0,ESAM,ZC3H14,NCOA5,NUFIP2,WDR82,EED,NKX3-1,SRSF1,HMG20A,SNRPA1,HNRNPL,CTNNB1,DDRGK1,WWP2,CDC26,BAZ1B,IFI16,MAGOH,POU5F1,MGMT,AGR2,DUS4L,TOP2B,RPL31,HNRNPDL,CCAR1,VDAC1,SOX2,NCSTN,SUPT5H,MAX,ZRANB2,SMARCB1,MTA2,PDHA1,IRF8,TRIM24,UBE2I,EIF2AK2,CTTN,EIF4A3,CCNF,STUB1,VIRMA,AANAT,NDN,MAGOHB,USP14,PPP1CC,NONO,CDC16,PIM2,CDC73,TDP1,MTDH,PPIH,PRPF4,SIRT7,PRIM2,RPA3,PIAS1,FBXW7,NF2,EIF3J,CCNA2,NFYB,TPT1,ATG16L1,RPS14,TXNL4A,MACROH2A2,WTAP,LSM2,CDK1,LMNA,JUP,TOX4,H2AZ1,CWC15,ZBTB2,MDM2,POLE3,CDK9,NCBP2,TOP1,THOC1,HDAC6,IRF4,GRSF1,H2AC14,IRF9,BRD3,TIAM1,ZC3H11A,RPL23A,TCOF1,PQBP1,MSH6,SNRPG,THRAP3,CTNNBL1,SEM1,LSM4,DDX39A,TBK1,FBP1,RNF181,POLR2G,ILF2,TOPORS,ZMAT2,SNRPD2,SNRPD1,ELK3,EIF3K,CPSF1,ERH,RBBP4,EIF4A2,MCM4,MCM3,RFC5,PRPF31,CUL3,GRB10,NFYA,NLRP3,BRCA1,CFDP1,COIL,POLA2,UCHL3,CDKN1A,SUPT4H1,PPP1CB,RND2,ACTL6A,SLC25A3,MFAP1,ADNP,USP39,HP1BP3,PHB1,PSMB5,FOLR1,BUD31,TRA2A,HNRNPA1,NDC80,DPY30,PRPF19,LHX2,BCL2L1,HNRNPD,SKIC8,DDX23,JAK1,FAM76B,PCNA,HNRNPA2B1,SSRP1,PPWD1,MCM6,GTF3C3,DHX16,TRIM26,RCVRN,GTF2E2,JUN,RAF1,ZNF263,FEN1,TMEM14B,POLR2C,POLR2D,RPS11,RBPJ,CHMP4C,EZH2 |
| 1.279e-13 | -29.69 | TEX101 (testis expressed 101) | protein interactions | 83639 | 255 | 127 | 19454 | 5460 |
TAGLN2,EIF4A2,STAT1,RPL35,TUBB,PSMD6,ACTB,PAPSS2,CYB5R3,DPEP1,SERPINH1,BRCA1,RBM27,SAMHD1,RPL39,PSMD1,CUL3,PMPCA,PYGB,SKP1,HNRNPA0,RABAC1,XRCC5,SLC25A3,HSD17B6,CD59,NCALD,CCT7,CCAR2,SNX1,THY1,CYB5A,LAMP2,PSMD3,GSTM3,RPL6,CST3,STOML2,PSMD12,PDE6A,VDAC1,RUVBL1,PICK1,SCPEP1,RTCB,PRND,HSPD1,TMT1A,CCT8,SYPL1,NDUFA4,CYB5B,HGS,RPN1,CTSA,GFPT1,CYB5R1,PPP2R1A,F11R,LDHA,RAB14,CD47,CPT2,SLC25A4,PSMC5,PRSS8,UQCRC2,CYRIB,REEP6,RPL26,NONO,RAB2A,HSPA5,CLU,DPEP3,AOX1,MME,APMAP,EPHX1,RARS1,CYC1,COX6C,HSP90B1,TMX4,PSMC4,SYNGR2,EDDM3B,SEC22B,ARHGAP1,LMAN1,KLK3,CAV1,ARL6IP5,CAND1,TMED9,MIF,IZUMO4,ITGA6,SDHB,COMT,COX4I1,RPS2,PPIC,CD9,CD81,ATP1B1,GAPDH,DPP4,H2AC14,ISYNA1,PGAM1,COX5A,ATP5MG,CAPZA1,HUWE1,PSMA5,CSE1L,ABCE1,PCYOX1L,PSME1,APEH,SURF4,ACTR2,ACTR1A,FBP1,SERPINB9,CD38 |
| 1.305e-13 | -29.67 | Dppa3 (developmental pluripotency-associated 3) | protein interactions | 73708 | 284 | 138 | 19454 | 5460 |
RPL4,ZC3H15,MARS1,RPL27,HELLS,IDH3A,MRPS34,P3H1,METTL14,EIF2B3,RPL26L1,RARS1,RBFOX2,MRPL10,CDC42,COPE,RPL13A,RPL22,EIF2AK2,ENO1,CTNNA1,EIF2S2,RPS12,IGF2BP1,ATP1A1,RALB,RPL7A,PPP1CC,NONO,CAMK2G,NUP107,ATP1A2,CSE1L,RPS13,SLC25A10,SLC16A1,MRPS18B,RPL23A,EXOC3,CHAMP1,TFRC,DMAP1,ACTR2,ACADSB,ILF2,HADH,RPL15,METTL15,CAND1,EIF2B5,FUNDC2,MRPS23,MRPS9,SDHB,ARL10,KRR1,COX20,TES,MUL1,TUBG1,RPL24,AKAP8L,KPNA1,DNAJC7,MRPS7,DDX39B,EXD2,HADHA,ACAA2,SIGMAR1,NDUFA5,FDFT1,LAP3,RPL27A,ZC3H14,MTX2,ZNF362,MATR3,STAT1,RBBP4,PSMD6,SIAH1,RPL19,CHP1,VDAC2,MTG1,RMDN3,RPS9,RPS26,HNRNPAB,PSMA4,MLF2,BAG3,VDAC1,MCM6,MRPS17,ZYX,RINT1,NDUFA4,CDK5,RTCB,RPS24,STIM1,NME1,UCK2,PRKAG1,POLR2C,RPL18,ETFB,TRAF2,CYB5R1,GFPT1,NCSTN,NUP153,NOP58,SNRPD3,RPRD1A,PHB1,SRSF1,MYEF2,PSMB5,WDR82,XPO5,MAGED2,HP1BP3,CSTA,RHOG,HNRNPD,HAX1,DDX1,PRDX1,RAB32,PSMD3,RPL6,MRPS35,YWHAH,YWHAG,EXOC1 |
| 1.324e-13 | -29.65 | HSPA9 (heat shock protein family A (Hsp70) member 9) | protein interactions | 3313 | 658 | 271 | 19454 | 5460 |
PHB1,FOLR1,SDHAF2,GJA1,HYPK,NUP35,DHX15,CACYBP,NDUFS8,STOML2,MRPS35,CLPX,PDIA3,ATG7,HNRNPA1,FGF1,PSMD10,RHOG,HAX1,HNRNPD,ARGLU1,HSPD1,COX8A,HINT2,ACVR1B,TRIM37,ETFA,G3BP1,IMMP2L,PSMD12,TXNRD1,RAF1,PPP2R1A,NGB,NME1,NDUFS6,BZW2,CHMP4C,EZH2,POLR2C,RAN,CYB5R3,AP2M1,ACTB,GNB1,CUL2,GRB10,CUL3,PYCR1,MTG2,ACO2,RHOB,BRCA1,RIT1,SP1,HSP90AA1,PAXX,TNFAIP8,DNAJC3,PSMA3,HADHA,GPC1,HSCB,PSMC1,FBXL4,ALKBH3,CDKN1A,PRDX3,PPP1CB,ATP5PO,PPARG,NDUFA5,HEXB,RCHY1,AIFM1,DCUN1D1,KCTD15,G6PD,CDK9,GRSF1,MOV10,NFKB1,HDAC6,PSMD7,DNAJC4,SFXN1,RAB1A,FAF1,HSD17B10,DNAJC30,HSPE1,VRK1,FBXO25,NDUFA2,TRIM6,FBP1,MAP2K3,MLLT6,MAP1LC3B,EEF1A1,NDUFS3,GPX7,EIF4A3,CTTN,ENO1,STUB1,CCNF,MSN,ZBTB18,COPZ2,GTF2A1,YES1,LDHA,VIRMA,ASTN1,FERMT2,PYCR2,CSK,AR,DNAJC8,FBXO7,RUNX1,ATP5F1A,ZSWIM7,DNAJC19,CDC73,SIRT7,DVL2,SOD1,RPA3,INPPL1,MAVS,HMGB1,FBXW7,NF2,YKT6,LSM8,CCND1,ATG16L1,CDK7,DENND2D,METTL14,HSP90B1,WTAP,HAUS2,RARS1,DUSP6,PRCC,EED,SUMO2,TRIR,RPS10,HNRNPL,ELK1,DIRAS2,GSTM3,IFI16,DDRGK1,CTNNB1,YWHAG,XPO1,NDUFV2,FKBP4,MAGOH,HSPB1,POU5F1,CBL,PABPC1,CCT8,SCPEP1,DNAJB4,VDAC1,KRAS,HNRNPF,MED9,ETFB,EEF2,SOX2,PDHA1,METTL21A,NDUFA12,DLST,PSMD6,ATP5F1B,LDHB,CDKN3,MYC,BTF3,ATG3,PSMD14,KIAA1191,DNAJB6,OSGEP,ICAM1,EP300,HDAC5,HSPA8,PHB2,ADRB2,STAU1,NDUFS2,UFL1,MRPS7,GINS3,MTF1,FUNDC1,PIH1D1,ALYREF,AIP,SSBP1,MRPS9,SHPRH,FZR1,CAND1,DNAJC1,VCPKMT,MYL12A,COX5A,DNAJB2,KARS1,TPM3,GAPDH,COPS5,SHC1,TUBG1,MAP4,USP15,NEDD8,MEPCE,TP53,INSIG2,KBTBD4,RRM1,MVD,UBL4A,H2AX,CBX3,TFCP2,RNF8,GRPEL2,ADRM1,SRC,SMURF1,CDC20,PTPN11,AKT1,MAT2A,CFL1,TRIM23,RC3H2,SPOP,KCNJ2,UBE2H,ATP1A1,BAP1,DLAT,RNF113A,CRYL1,NME4,DNLZ,HSPA5,MARS1,GRPEL1,EIF4E,CAPN1,CFTR,NEK2,RNF146,RPA2,UBE2M,HEXIM1 |
| 1.438e-13 | -29.57 | LAMP1 (lysosomal associated membrane protein 1) | protein interactions | 3916 | 635 | 263 | 19454 | 5460 |
ARF6,CAV1,PTPN1,HACD3,SRPRA,EHBP1,CDCA3,PROM1,TMEM184C,SLC2A1,ESYT1,TIAM1,OSBPL8,RELL1,TMEM199,LAMTOR2,EMC4,RAB23,DAG1,CTNND1,ADD2,STX8,RAB1A,EHD4,DLG1,RNF167,SNAP23,EMC2,HSD17B10,IGF1R,SHISA2,TRAPPC13,ILF2,CASK,CCDC47,LBR,MAP1LC3B,SLC29A1,RAB14,SNX3,YES1,TECR,FERMT2,VIRMA,ASTN1,SEC63,VAMP3,PLP1,CTNNA1,PRKRA,SDF2L1,LGALS8,AP2A1,EPHA2,RETSAT,CTSD,SEC13,DEPDC1B,HMOX2,DNAJC8,NF2,YKT6,PIK3R2,CHMP2B,CDC42EP4,TMEM209,RPA3,MTDH,SPCS2,ITGA2,JUP,PTP4A2,STOM,METTL14,SLC12A2,MET,RARS1,RABL3,UBA52,SEC22B,PIP5K1A,ARHGAP1,CNP,CDK7,SNX1,SPTAN1,TMEM237,WDR6,FBXO32,GJA1,MAP1LC3A,GPR137,NCR3LG1,CDK5RAP3,ELP6,HAX1,PIK3R1,HNRNPA1,WDR11,AP1M1,SAR1B,AKT2,SLC2A8,PLCB1,EZH2,STIM1,VAMP2,RPN1,STX12,ENPP4,PLD3,ARFGAP1,RAF1,MARCKSL1,TULP3,LRRC8A,LAMTOR3,LGALS3,CHP1,GNB1,FAM91A1,AP2M1,WDR20,SLC7A11,SCFD1,NTRK3,ILK,VEZT,NIBAN2,PIK3R3,TM9SF4,PKP4,RAB11A,MRPL16,CYFIP2,STX7,DNAJC3,BET1L,VAPB,CRYAB,HEXB,FKBP10,FAM3C,PGRMC1,NOTCH2,EHD1,SLC48A1,RAB6A,VTI1B,MIOS,SVIP,FCHO2,LMAN1,STX6,SLC38A2,TMPO,SURF6,STT3A,ITGA6,AIP,CAMLG,SLC39A10,ADD1,TRAPPC3,NOS1AP,DPP4,EDEM1,AKAP12,RAB3B,SRPRB,SLC6A8,PALM2AKAP2,SLC16A1,RAB13,STX18,TFRC,PIK3CA,CCM2,NHERF1,DISC1,SNAP29,UBL4A,TP53,MECR,UBIAD1,H2AX,ROCK1,ACP2,SRC,NECTIN2,ALG2,ATP1B3,ATP1A1,SNX5,RAB2A,TNFAIP3,ARHGAP21,GORASP2,FTSJ1,GRPEL1,PIP4P1,HSPA5,SEPTIN6,LIN7C,ITM2B,RPA2,VIPAS39,LEMD3,CSNK1G3,SLC35F6,SPTBN1,CDC42,CFTR,RAB1B,VAMP7,PTK7,TNIK,C2CD4C,STX5,LAMP2,SLC38A7,PTDSS1,YWHAH,PPFIBP1,CTNNB1,TENM3,DDRGK1,EPHA4,SLC20A2,ROCK2,VAMP8,TMEM87A,EFNB1,EWSR1,SEC11A,TRIM11,RAB4A,HGS,STBD1,ALG5,NCKAP1,ATP6AP2,FAM83B,LAMTOR1,SPCS3,OSGEP,SLC38A1,RPL39,RALGAPA2,SLC30A5,STX16,SLC1A3,EMC1,RER1,SLC18B1,ITGAV,ABCC5,TMEM106B,HSPA8,PLAA,CSNK1A1,USP6NL,SLC16A10 |
| 1.510e-13 | -29.52 | FAF1 (Fas associated factor 1) | protein interactions | 11124 | 330 | 155 | 19454 | 5460 |
PHB2,YTHDF1,NSFL1C,EEF1G,PSMC1,SKP1,CD40,HSPA8,DDX5,EP300,VAPB,ANXA7,CDKN1A,TCEAL1,ATP5F1B,ACTB,TUBB,LMBR1L,VDAC2,CYB5R3,FAS,FBXW11,H1-10,YWHAZ,HSP90AA1,NLRP3,ILK,CREBBP,CUL2,LDHB,CUL3,HNRNPAB,SAMHD1,MCM3,MLF2,UFD1,G3BP1,CHCHD2,HNRNPF,VDAC1,RUVBL1,RPS4X,RFC3,SLC25A5,HSPD1,HNRNPA2B1,PABPC1,CCT8,TRIM21,SLC2A8,PDIA6,TUBB4B,PLS3,RNF126,NLRP2,ISG15,FAF2,ERLIN2,EEF2,HNRNPL,KCTD10,TCP1,CACYBP,CCT7,HSP90AB1,WDR6,RPL8,SRSF1,PHB1,PRCC,SWAP70,KRT8,ATP6V1A,IKBKB,ARHGAP5,VCPIP1,UBXN6,STOML2,BABAM1,WWP2,YWHAG,HNRNPA1,YWHAH,CTNNB1,QPCTL,STK38,RPL4,HMGB1,ZC3H15,UGP2,HSPA5,BAP1,RPA3,PPM1G,PGK1,TNFAIP1,RPLP0,SUMO1,UBA52,BUB3,LDHA,NR1H2,CSTF3,UBB,VIRMA,STUB1,RPS3,OPTN,CTTN,ENO1,CSNK2B,UBE2I,SPOP,CDC73,OAT,IGF2BP1,AKT1,CARS1,SEC13,RPL7A,ATP5F1A,RUNX1,ST13,NONO,TUFM,NEDD8,HNRNPK,SRPRB,TGFBR2,MEPCE,SNIP1,FAF1,SLC25A11,HSD17B10,CBX3,UBL4A,YTHDF2,RAP1A,RPSA,TAF1D,EEF1A1,UBXN2B,MIOS,CDC5L,SYNCRIP,EEF1B2,CD274,RAP1B,SEC23A,RPL24,KARS1,EDEM1,CSNK2A1,GAPDH,KLHL22 |
| 1.522e-13 | -29.51 | cytoplasmic translation | biological process | GO:0002181 | 126 | 77 | 18204 | 5365 |
RPL9,RPLP2,RPS29,EIF2D,RPL19,EIF3J,RPL3,RPL28,RPS4X,EIF2S2,RPL12,RPL35A,UBA52,RPS27A,GTPBP1,RPS7,RPL22,RPL26,RPL39,RPS15,RPSA,ZC3H15,RPL8,RPS17,FAU,RPS14,EIF3D,RPL23A,EIF2B3,NCBP2,ETF1,RPL29,RPS3,FTSJ1,RPL35,RPS10,DRG2,RPL27,RPL13A,EIF4A2,RWDD1,RPL7,RPS16,RPS13,RPL10,RPS24,RPL37A,RPL15,RPS28,EIF3K,EIF2B5,RPS2,RPL23,RPL10A,RPS12,RPS23,RPL32,RPS11,RPL4,EIF3E,RPL17,RPL18,RPL27A,DRG1,RPL24,RPS20,RPS9,RPL6,RPL31,RPS26,RPL7A,RPL26L1,RPS5,EIF3G,RPLP0,EIF2B2,RPLP1 |
| 1.549e-13 | -29.50 | RPLP2 (ribosomal protein lateral stalk subunit P2) | protein interactions | 6181 | 371 | 170 | 19454 | 5460 |
SRP72,DNAJC2,RBM34,RPL15,MAP1LC3B,H2AX,TP53,RPSA,UBL4A,FBP1,RPL17,MEPCE,RPS13,VRK1,NEDD8,RPL3,RPL23A,RPL10A,RPS2,RPL24,SNRNP70,TUBG1,HDAC6,COPS5,CD81,EMC4,MOV10,ENY2,SURF6,RBM42,TMPO,RPS27L,CAND1,RPL35A,DNAJC1,RPS16,FZR1,DCUN1D1,LDLR,RPL12,SRP14,MACROH2A2,RPLP0,HEXIM1,RPL26L1,UBE2M,WWP1,USE1,METTL14,JUP,SMYD3,CFTR,CDK7,CDC42,UBA52,TPT1,GTF2H4,LIAS,ATG16L1,RPS14,UTP23,HSPA5,FBXW7,HMGB1,RPL4,H2AC13,DGCR8,RPS15,NPM3,RNF113A,SIRT7,RPL27,BAP1,DNAJC19,UBE2H,RC3H2,MECP2,SPOP,ATP1B3,USP14,PPP1CC,RPS17,RPL26,RPL7A,SRPK2,VIRMA,RPL22,SRC,RPL13A,MRPS21,PTEN,RPS20,PRKRA,METAP2,CCNF,PSPC1,RPS3,RPS23,SART3,RPL18,RPS11,NGB,EZH2,RPS7,DNAJC25,JUN,RPL29,MAGEB10,B3GNT2,RPS4X,RPL28,G3BP1,TNF,KRAS,RPS24,EWSR1,PABPC1,RPL31,DICER1,RPL23,DRG1,RB1CC1,KDM2A,CTNNB1,DDRGK1,HNRNPA1,YWHAG,WWP2,RPL6,RPL7,LYAR,RPS10,RPLP1,RPLP2,PHB1,SRSF1,RPL8,FOLR1,RPL9,PIH1D1,CNDP2,EMC9,PPT1,MRPL12,H1-5,RPL27A,G3BP2,SSR3,STAU1,UFL1,RPS28,RIT1,H1-1,ICAM1,RPS26,RPS5,BRCA1,ZNF668,BTF3,CUL3,CUL2,MYC,RPL19,ESR2,RPL10,RPL35,RPS9,SEC61B,RPL37A,CMTR1 |
| 1.600e-13 | -29.46 | STX5 (syntaxin 5) | protein interactions | 6811 | 253 | 126 | 19454 | 5460 |
VAMP5,RAB2A,GORASP2,CSGALNACT2,NAPA,TNFRSF1B,SGTA,TMEM74,SEC63,SEC22B,CHST7,ST7,CDC42,SSR1,USE1,STX17,FGFR1,RPA2,LMNA,PTP4A2,PML,RPA3,DVL2,RAB9A,DERL1,SYVN1,LPAR1,YKT6,NAPG,SLC25A46,KXD1,LAMP3,ESYT1,ARL10,PTPN1,RAC2,HSD17B11,SNAP25,VTI1B,DNAJC1,TMED9,ARF6,CRB3,CAV1,LMAN1,STX6,TMPO,TP53,SNAP29,PSMB9,CLEC2B,TMEM165,TMEM31,STX8,SNAP23,STX18,RAB3B,SRPRB,FKBP8,GALNT2,ARF4,PSEN1,CHST9,RAB11A,LMNB1,BRCA1,LAMTOR1,SCFD1,NTRK3,LMBR1L,SEC61B,RETREG3,RMDN3,DKK3,REEP4,MANSC1,TNPO3,LRIF1,BET1,PGRMC1,GOSR2,FAM234A,STXBP1,RND2,INSYN2A,OTULINL,SEC62,SEC22A,TMEM266,VAPB,JAGN1,BET1L,RAB5A,OR1M1,NSFL1C,HSCB,GOSR1,PXMP2,STX7,RAB5C,PLPP4,ATG9A,LAMP2,YWHAH,RHOG,STX1A,VCPIP1,PEX3,RAB35,FAAP100,GJA1,CX3CL1,NUP35,ARFGAP1,DNAJC25,RAB4A,PDHA1,STIM1,RPN1,STX12,TMT1A,CYP2C9,ACADS,KRAS,HS2ST1,SAR1B |
| 1.621e-13 | -29.45 | MRPS26 (mitochondrial ribosomal protein S26) | protein interactions | 64949 | 435 | 193 | 19454 | 5460 |
PRDX3,TIMM29,ATP5PO,NDUFA5,SLC25A3,EXD2,ATP5IF1,HADHA,HSCB,NOP53,AUH,MTG2,CUL3,PYCR1,PMPCA,NOA1,HTRA2,RPS9,MRPL23,RPL35,PARL,RPL19,NDUFAF4,HSDL2,DLG3,NDUFS6,HSPD1,PREPL,HNRNPA2B1,THNSL1,HINT2,HECTD3,RPS24,MRPS11,COX8A,SRSF7,ETFA,MRPS17,IMMP2L,CLPX,MTRF1,STOML2,MRPS35,INSYN1,TRA2A,MRPL18,RHOG,GATD3,MPP1,NDUFS8,RBMS2,KLF12,MRPS34,LMNA,GRM2,MMADHC,ZNF574,MTRES1,SQSTM1,PDHB,MRPL17,HMGB1,RPL4,CRYZ,POLDIP2,MRPL20,PYCR2,TUFM,DNAJC19,MRPL53,ACAT1,MGST3,RPL13A,VIRMA,NDUFA2,MRPL11,MAP1LC3B,PPIF,AURKAIP1,APOBEC3D,BCS1L,NDUFS3,ILF2,CIBAR1,MRPL49,RPL23A,HSD17B10,MRPS18C,MRPL22,FASTKD5,GRSF1,MOV10,SUV39H1,DNAJC4,AIFM1,SRP14,RCHY1,KRR1,PRR3,CGAS,MRPL50,DBT,ATP5PD,MRPL24,MRPS23,ZBTB2,SYK,NDUFAF3,MRPL12,NGRN,UFL1,NDUFS2,MRPS7,MYC,HNRNPAB,BTF3,MRPS25,MCAT,TACO1,CCDC90B,MTG1,DLST,MRPL13,ATP5F1B,RPL10,ETFB,H1-3,SOX2,PDHA1,NDUFA12,NDUFB5,KGD4,HNRNPDL,RPL6,NDUFV2,MRPL9,DDRGK1,HNRNPL,PNPLA8,RMND1,MRPL10,QRSL1,FGFR1,HEXIM1,KLF4,TWNK,DLAT,GFM1,NME4,MRPL41,MRPL40,GRPEL1,ABCC2,NDUFAF2,MRPS16,RC3H2,IGF2BP1,UBE2H,MRPS28,MRPS21,ATP5PB,MRPL47,HADH,METTL15,GFM2,MRPL52,ATP5PF,RPL3,MRPS18B,CLPB,THG1L,H3C1,PDE12,MRPS33,HNRNPK,MEPCE,RPL17,COX5A,TMEM70,CHCHD1,SNRNP70,NOL12,MRPS9,SSBP1,SYNCRIP,MGME1,COX4I1,ALYREF,TRMT10B,CAND1,FZR1,RBM42,SURF6 |
| 1.625e-13 | -29.45 | regulation of cell population proliferation | biological process | GO:0042127 | 1790 | 664 | 18204 | 5365 |
MIR223,ACVR1C,POLD4,CXCL9,FOXP1,SLC7A1,IL12B,MIR185,HAPLN2,IL6,CSK,ID4,TP53INP1,STAMBP,BAX,MMP9,BTG1,CD86,ASPM,PNP,JUN,JUNB,PRL,ACTL6A,DHPS,FUT1,AKT3,FOXP3,CD274,MIR449A,E2F4,TMEM196,MTA3,SPRY1,MIR10A,PRNP,VEGFC,GPR37L1,PELI1,EMC10,GNG5,PAX6,SSBP3,WNT10B,TXNIP,NMI,MIR204,CD80,MIR129-1,BAP1,LDOC1,KCNH1,RERG,EMP2,RTN4,MIR548C,FMC1,TLR9,IFNK,TNFRSF1B,SMARCD3,LST1,RGCC,ZBTB16,MSX2,SELENON,AQP11,CDKN3,SLC39A9,SFN,NACC2,MIR519D,MIR96,CD9,DNAJB2,FGFBP1,MIR30B,MIR21,INHA,ECRG4,CDC73,PDCD10,BRD9,IGF1,NFKBIA,HMX2,ROMO1,GRPR,OVOL1,TAX1BP3,CALR,BOK,MIR675,WDR77,BAK1,VDR,GID8,GSTP1,TNFAIP3,RBBP4,CTNNB1,TOX,CCND3,GPX1,CCL24,CXCL11,CDC7,VSTM2A,WNT7A,PPP3CA,LMNA,MIR182,IL1B,TGFB3,AKT1,H2AC6,RPS4X,ITGA2,AMELX,SMAD4,CEND1,PTEN,LIMS2,JAK2,TSG101,BCL2L1,MED31,NRP1,PLA2G5,TIRAP,B4GALT1,BST2,FGF1,MIR125A,STAT1,ACER3,GLCE,DVL2,B4GALT7,MIR10B,MIR448,ROGDI,BAD,MIR320A,ODAM,TNFSF13,XBP1,KIT,GNAI2,H2AC4,PID1,EIF2AK2,MIR221,ATP5IF1,MIR130A,IL2,TGFBR2,MIRLET7B,SS18,CCND1,MIR492,CRKL,TRIM24,AR,MIR497,MIR873,PIK3CA,CD47,TIAM1,IFT52,MIR34B,ARHGAP5,BIRC5,IFNG,PRKRA,CACUL1,PDCD4,TES,MIR143,MIR15A,MIR135B,CAMP,SST,RB1CC1,IL18,NME1,TNFSF12,ZNF609,ANGPT1,MIR34C,SRC,SH3BP4,ADRA1A,PHB2,RNF41,CD40LG,PMP22,LEP,FASLG,MIR140,CD200,KRIT1,REG1B,TICAM1,MIR137,IL15,COX17,AKR1C2,SMARCB1,MECP2,BMPR1A,MIR181C,FGF23,CD248,VEGFA,IL23A,BMPR2,ADGRG1,CCAR1,TIMP1,MIR29A,NF2,SETD4,CUL3,NR2E1,PIK3R1,MIR30E,OSM,IRF1,NIBAN2,NTRK2,NTRK3,MIR218-1,NDUFAF4,RXFP2,CTNNBIP1,TNFRSF9,TRNP1,SHOC2,CCNB1,CGRRF1,VSIR,SLC7A11,DUSP22,ATRAID,MIR101-1,MIR24-1,CERS2,SMAD3,WNT2,TRIM32,CCN3,GPAM,TFRC,RAB33B,BIRC2,DUSP1,CNOT6L,FA2H,EGLN3,LACRT,SELENOK,TMIGD3,SERTAD1,EGFL7,TMIGD1,HILPDA,MIR205,FGF16,CLU,KLF10,CCL23,CD40,MINAR1,SAV1,DERL2,EAF2,TESC,FCGR2B,NOG,HDAC6,NKX3-1,FBXW7,NME2,ATF3,STK11,TAFA1,HCLS1,DISC1,CCL2,NPPC,BMPR1B,NHERF1,IL2RA,HPGDS,PML,POU1F1,NUP62,MIR141,CACNB4,MIR16-1,TERT,ARG2,P3H1,CD38,MIR222,HP1BP3,FKTN,CYP1B1,AGGF1,TLR2,MARCKSL1,TRAF6,NLGN2,SFTPD,RNF10,CCL19,PIAS1,PTHLH,DPP4,CDK4,CTLA4,VIP,STAT5A,TRIB1,MIR378A,XRCC5,CCL5,CASK,SOS2,EPHA4,MIR126,IGF1R,FLCN,SFRP1,MYC,PTGER2,IFT172,FERMT2,PTGES,NUPR1,PRDX3,FTH1,FZR1,CDC42,ATP5F1A,MIF,FRZB,PDCD5,SASH3,APLN,CDK1,CNTFR,OSR2,LILRB1,KLF9,MIR132,HTR2A,IL12A,SCG2,HEY2,MAB21L1,BTN2A2,CSF2,IL6ST,STK3,TNFSF8,OPRM1,PRDX4,TYROBP,CAV1,EEF1E1,ZBTB17,RBFOX2,GPBAR1,HTR1A,CD28,PTPRZ1,RPS9,PIM2,VGLL4,CDKN2D,ODC1,CAV3,MSTN,MEF2C,MIR150,RUNX1,ZMPSTE24,IL20RB,MIR208A,TMEM127,IL4,TACR1,IFT57,MIR342,SMAD2,MYD88,FAM98A,IGFBP3,S100A11,CLDN1,CD46,FXN,MIR149,MIR146A,LILRB4,DGCR8,CD81,HBEGF,PTN,CD209,PDE1A,KRAS,NOTCH2,SRPK2,TGFB2,IL1A,FGF10,IRF6,RPRD1B,NCK1,MIR9-1,ADAMTS1,TMEM115,SOX2,PTPN22,GAS8,SPINT2,RPA3,FABP7,DHX9,STAT6,CDH13,FOLR2,MIR152,SEMA5A,GREM1,HAND2,CXCL1,PROX1,TNFSF18,MIR29C,MIR200C,IL5,SMAD1,CHRM1,KDM1A,CAV2,SKAP2,ING5,MIR339,CTBP1,MAP2K1,PPP1CC,SHC1,HGS,LTA,FOSL2,TOB2,RNF126,BTG3,REG1A,CDCA7L,MIR20A,RGN,GHRL,CSNK2A1,PROK1,SOX9,STAT2,NDFIP1,PDF,FZD3,CTNNA1,OGN,DICER1,EFNB1,TOPORS,BECN1,SNAI2,IFI35,SLC35F6,DLG3,MVD,CNOT6,CHST11,DLG1,MAFG,CXCL8,MDM2,SDC4,MIR188,SDCBP,MIR133B,ACTL6B,ST6GAL1,TP53,IDO1,STK4,CIAO1,MAP3K3,SYNJ2BP,MIR1-1,CLEC7A,IL21,MITF,IL13,ATG101,SSR1,SOD2,MIR34A,RAC2,GABBR1,ATXN1L,ACKR3,ITGAV,FGFR1,CNOT8,VASH1,TSHR,SIX5,FGF22,ADORA1,ADORA3,CCL8,MIR590,KLF4,CCL11,APLNR,TLR4,CER1,CDK6,AZGP1,PTGDS,SLC6A4,MIR638,EPO,TPBG,S100B,WDR6,LGALS3,MNAT1,MIR335,RNF139,CNOT7,CYP27B1,EGR1,TGFB1I1,IL34,B2M,MIR195,CHRNA7,EZH2,CHRNB2,IL3,LHX2,IL7,CDKN1B,PDE9A,MIR193A,S100A6,TSPO,BTG2,PGR,IRAK4,RHOG,GPNMB,JUP,MIR711,PRKCQ,RNF187,MIR503,EMX1,PPARG,JAML,UFL1,SP1,SFRP4,RPL23,EPCAM,CCNA2,ADIPOQ,TNF,LBH,FGF17,CCR3,TWSG1,FGF3,DDRGK1,HMGA1,ACTB,XCL1,IL10,PTGFR,RBPJ,MIR1298,CX3CL1,RAF1,SLC39A10,MSX1,DBH,TRAPPC14,CX3CR1,MIR145,NMBR,CDKN2C,AVPR1B,PHB1,RPS3,ING1,DDAH1,MIR495,CD1D,BCL7B,HMGB1,FGF7,LBX1,CXCL12,BCL6,PLAC8,EMILIN1,MIR98,DUSP10,MZB1,AGER,ZNF304,MIR361,MIR23A,PYCARD,PLG,HRAS,CFDP1,INPPL1,TNFRSF14,CXCL10,CDKN1A,SPHK2,RBM5,EID2,ILK,CITED1,MIR301A,RB1,NPY5R,SLC25A5,MIR424,VIPR1,MIR214,MIR17,DDR1,GJA1,PRKCA,PPM1D,SLC25A27,AIF1,CCR2,F2,CLDN3,CAPN1,MIR657,PDCD1LG2,BCL7C,CSNK2B |
| 1.653e-13 | -29.43 | TAX1BP1 (Tax1 binding protein 1) | protein interactions | 8887 | 333 | 156 | 19454 | 5460 |
DEK,DUSP3,UBB,RPL13A,RPS12,ACAT1,MRPL53,CCNF,OPTN,SERPINB1,LGALS8,AR,NTAQ1,LRRC73,RPL7A,EMILIN1,TNFAIP3,CXXC1,GABARAP,MRPL40,HMGB1,RPL4,LITAF,MAVS,SQSTM1,GPX4,RNF34,MAPKAPK3,NBN,HELLS,RARS1,CHMP1A,GABARAPL2,FTH1,CFTR,AGO1,SEC22B,FAM161A,ARHGAP1,UBA52,EEF1E1,ATP5PD,CGAS,TOP1,RPS16,TRIM45,DSTN,AIP,ESYT1,LYPLAL1,USP2,FOXC2,CMSS1,ORC5,KXD1,CAPZA1,MPST,MDC1,TOM1,TOLLIP,HSPE1,RNF115,TCEA2,NSDHL,RAD23B,APEH,TBC1D4,STARD13,SH3GLB1,TMEM31,RP9,CBX3,AZI2,MAP1LC3B,RAP1A,MRPL11,RPSA,TBK1,APEX1,PSMD6,REEP4,TAX1BP1,RMDN3,SCNM1,DLST,COP1,OSGEP,YWHAZ,MYO6,ATG3,CCNQ,OTUD7B,BTF3,HSD17B3,RIOK2,CUL2,CUL3,FTL,RNF11,POLA2,PHB2,GPC1,CCDC86,TAPBP,HSPA8,BIRC2,RPS28,NMRK1,TRAPPC6A,FKBP10,TBC1D17,PCLAF,SDC2,LMO3,MRPL12,SEC62,GOSR2,NOTCH2,TOMM22,LRWD1,PEG10,SNX1,NRSN1,TSG101,SWAP70,SDC4,RPL23,RB1CC1,MED4,HNRNPD,TRAF6,IKBKB,CTNNB1,ATG7,PLPP4,RAB5C,HMGA1,LAMP2,SACM1L,RAB18,RNF26,RPS27A,UBE2A,FAM168A,HSD17B8,TRIM21,LDLRAD4,DNAJB4,CCT8,RNF126,RIMOC1,KDELR1,ERLIN2,GABARAPL1,TRMT1L,RAF1 |
| 1.717e-13 | -29.39 | RPL21 (ribosomal protein L21) | protein interactions | 6144 | 325 | 153 | 19454 | 5460 |
RPS13,MEPCE,PTGES3,RPL17,VRK1,RPL23A,ABCE1,RPL3,ILF2,SRP72,TFCP2,DNAJC2,MAP2K3,EEF1A1,RPL15,FBP1,KBTBD4,UBL4A,TP53,RPSA,CDK9,RBM42,FZR1,RPL35A,DNAJC1,RPS16,CAND1,RPS27L,RPL12,RPL32,RPS2,RPL10A,TUBG1,EID1,RPL24,SNRNP70,CSNK2A1,COPS5,HDAC6,API5,ENY2,KARS1,PIAS1,HSPA5,RPS15,HMGB1,FBXW7,RPL4,RNF113A,BAP1,RPL27,RPA3,SIRT7,PML,RPLP0,RPL26L1,HEXIM1,RPA2,JUP,METTL14,GRM2,CDK7,CFTR,RPS14,TPT1,EEF1E1,RPL22,NDN,RPL10L,RPL13A,GSK3A,PRKRA,RPS12,RPS20,PTEN,PSPC1,RPS3,METAP2,EIF4A3,PIM2,CALU,UBE2H,SPOP,RC3H2,FBXO7,RPL26,RPS17,PPP1CC,RPL7A,RPS27A,RPL28,RPS4X,G3BP1,KRAS,UBE3A,RPS24,SLC25A5,RPL31,RPS11,MTMR2,RPL18,RPS23,CHMP4C,RPL29,RPS7,EEF2,B3GNT2,RAF1,E2F4,RPS10,LYAR,RPL7,RPLP2,RPLP1,RPL9,RPL8,PHB1,RB1CC1,MAGOH,DRG1,RPL23,FOSL2,XPO1,HNRNPA1,DDRGK1,MAP3K14,WWP2,RPL6,G3BP2,UFL1,STAU1,HSPA8,RAB5A,RPS28,PIH1D1,EMC9,RPL27A,PAFAH1B1,RPL10,RPL19,RPL35,RPL37A,RPS9,SEC61B,CMTR1,RPS5,RPS26,RIT1,BRCA1,BTF3,MYC,CUL2,CUL3 |
| 1.802e-13 | -29.34 | ORF8 (ORF8 protein) | protein interactions | 43740577 | 427 | 190 | 19454 | 5460 |
RPN1,PGGT1B,PLD3,NEU1,ACTN4,ERLIN2,TAPBPL,RETREG1,HSPD1,HNRNPA2B1,PCNA,SRSF7,ERP29,BAG2,TMEM30A,RPL23,PDIA3,HNRNPA1,SPTAN1,ERLIN1,OS9,NPC2,MRTO4,VAPB,FKBP10,HEXB,WDR77,PGRMC1,PRDX3,THOC3,DNAJC3,TTC1,MYO6,LMNB1,SP1,RAB11A,GGH,MCM3,ACTB,TUBB,ABHD12,B4GAT1,FAU,PIGK,HSPA13,ACTR2,ADAMTS1,CCDC47,YTHDF2,EEF1A1,DDX39A,HUWE1,ERLEC1,ARF4,GALNT2,PRDX4,VPS16,SFXN1,AGA,POR,OSBPL8,CALR,PLEKHF2,THOC1,TOP1,NCBP2,TOMM70,CHID1,LMNA,P3H1,HSP90B1,HNRNPH3,MET,SEC22B,MRPL20,MGAT4B,SQSTM1,PPIH,H2BC12,ARPC2,EGFL7,SDF2L1,LGALS8,TUFM,LDHA,MGST3,TMOD3,TECR,TUBA1B,EIF4A3,ENO1,TRIM27,RTRAF,GANAB,ACAT1,SFXN2,ALB,HEXA,ETFB,CCDC134,VDAC1,POLDIP3,SCPEP1,MYO1B,PDIA6,CRTAP,TGFB2,PROS1,XPO1,PPIB,RPS10,EIF2S1,TOR1B,SRSF1,CORO1C,HEBP1,FAM8A1,EIF4B,PABPC5,EFHD1,GPC4,SEC62,CNPY3,EDEM3,TRA2B,EMC1,PHB2,SNRPA,DDX39B,XRCC5,SPCS3,SERPINH1,SNRPB,MLF2,TBC1D1,ATP5F1B,CBX5,ACAP2,VDAC2,ZNF862,ARPC3,SELENOF,TP53,MRPL47,RPSA,UBIAD1,CSE1L,TMEM33,FKBP8,NAE1,H2AC4,IGFBP4,KARS1,GAPDH,TPM3,RPS16,TMED9,LMAN1,SYNCRIP,STT3A,H2BC11,GALNT1,CHPF2,SPTBN1,IGFBP3,AIF1L,STK38,ST8SIA4,WDR55,GRPEL1,CLU,HSPA5,APMAP,PRDX6,DLAT,ATP1B3,OAT,ATP1A1,IGF2BP1,CSGALNACT1,CALU,SORD,NPTX1,CFL1,RPS17,CFL2,CHPF,UTS2,TXNDC12,EIF2S2 |
| 1.959e-13 | -29.26 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3720 | 1248 | 16828 | 4835 |
PPFIBP1,NUP35,PTGER1,MECP2,TFPT,RAB23,ALOX5AP,RIT2,OGG1,RGS6,SMARCE1,CCR3,SUMO3,CBFB,ASPM,UBE3A,ENO1,PKIG,JUN,WWP1,CALR,SNAI2,TNIK,RHOJ,CBLN4,SERPIND1,ORAI2,RNASEL,ARF6,FBXL7,LBR,UTP23,GNG3,CDK5,SPHK2,RCHY1,RNF26,RAB13,FGR,TOB2,RNF167,RAB33A,MAP2K3,DOK5,STYK1,TNFSF18,MFAP1,MXD1,RPL26,HCST,FBXO34,RAB14,BRMS1L,RIOK2,UBE2I,FOS,DYRK2,EGLN3,PNRC1,ZBTB16,F10,MAFG,RNF7,CCR5,SAR1B,CAPG,EZH1,RAB5A,PC,PRKAG1,HNRNPK,APOBEC3D,MAP3K3,NEK2,NFKB1,SAP30,MSN,POU5F1,PPP2R5A,FANCG,STAT1,ZNF507,RNF128,DICER1,PAX6,PTGES,PPID,RPN1,SYBU,SERPINB6,ADK,RALA,ANAPC13,PAFAH1B2,DUSP18,HDAC6,RNF39,TP53,PGR,KIN,ASCC1,PRDX6,SMUG1,HSPA14,CXCR4,GPC4,CXCR6,GNA14,CXCL10,USP14,SENP8,RAN,ASB3,PPM1B,RNF122,ZMYM4,BTG1,SERPINA5,FOXD3,TRIM35,BICD2,RHOG,FAM83A,ASB11,BNIP3L,RERG,RGS1,SDHC,CXCL14,ADAMTS1,COX7B,RRAS2,PPP1R16A,NUP153,PPARA,COPS7A,KPNA6,DDX42,RNF20,TOX,GNG11,PPP1CB,NFYB,ARF1,HMGB1,RABL3,PDCD5,DUSP6,SESN2,DAPK1,PML,MMADHC,NR1H2,ARF4,PLEKHA8,YWHAB,SERTAD1,LCP1,NLRP1,PPFIA3,CDKN1A,FOXN2,SKP1,FBP1,KDSR,DNAJC7,DNAJC27,CRKL,PLCL1,YWHAH,SOS2,DIRAS3,ADAMTS20,HDAC11,DUSP22,RAB1B,RGS5,TFRC,CKS1B,AUH,SNIP1,RGL1,SUV39H1,UBE2D1,FOXI3,TNFRSF14,LDHAL6B,HMGA1,PRKCB,RANBP10,DDX4,CAB39,KLK5,TULP3,BMPR1B,GNAI2,SPSB1,RBBP9,APOBEC3B,MLH3,FBXO11,TOP3B,PCBP4,FOXC2,CBX5,RAB32,PITPNA,CDK17,PPM1G,E2F4,BCL2A1,ATP6V1D,CDKN2D,TRIM11,PROM1,TOPBP1,TFDP2,C1D,G2E3,ZNF189,EEF1B2,PTPRZ1,RHOB,MAX,SUPT4H1,PCGF3,VPS39,CCNF,RAB9A,MEF2C,CTNNA1,RAB2A,ARL4A,SRSF4,TNPO2,IL7,LITAF,APPBP2,FUT1,RPRM,SNX12,IRF4,RAB9B,CCND3,RAB11B,ARL6,NEURL2,EZH2,INPP4A,FKBP10,CMTM7,SNX24,TP53INP2,MED23,USP13,LAMTOR3,STAT6,SMG5,RNF139,NUP62,RPS27L,FGF3,STK11,TESK2,DYRK1B,WIF1,PPP2R1A,RAP2C,SMAD3,DDX5,EIF4A3,DDIT3,SHC3,CDC26,IL6ST,CYTH1,CTNND1,TIMP1,KPNA2,DDIT4,SMYD3,UBE2F,STK38L,FOXP2,PIGC,RAB3A,FBXO25,SMAD9,PTPN5,USP30,JUNB,RAD23B,SCYL2,FOXJ3,RAB37,WEE2,VCPIP1,RNF14,PNP,RAB5C,DET1,DNAJC10,RAF1,TCEA1,STK38,BCAS4,CHN2,HSPA8,VMP1,ARHGAP19,CUL3,SSRP1,LMNB1,ERCC3,BECN1,MED21,FAS,ATF1,DNTT,RBBP4,OSBP,GOLGA5,XBP1,COX6A2,MAD2L2,CHMP2B,PAK6,TRIM24,ACSL4,GRB10,EED,CSNK1E,HSCB,TFEB,MED4,AKT3,BCKDK,POLD4,DNAJC4,PPP1R12A,COX4I2,UBE2S,ITGAV,CDKN2C,MXI1,USP5,NUP37,TRIM5,EIF4E,ARHGAP15,ANAPC4,RHOH,PIK3CG,DDX39A,COX4I1,IGBP1,AKAP12,FOXP4,RNF126,LDHB,LRRC4B,SNAPC3,BAK1,ELK4,CD274,FAIM,SMARCA5,DRAM1,FZR1,CORO1C,RACGAP1,SMAD4,NLRP2,HDAC3,PPP2R3A,RAB22A,AIFM1,UBE2V2,SNX14,AK5,RAP1B,RAD21,DNAJB4,SMC4,EGR1,UBE2M,TRIM10,TFE3,UBE2E3,ITGA6,CSNK1A1,FCHSD2,ACVR1B,CNTN1,PRKAB1,GNB4,PAX9,ALDH1A3,ACTB,SNX18,ANKRD10,CSNK1A1L,SOX2,LNX2,CLIC4,DERL1,RFC2,PIGK,EEF1A1,GAS2,FBXO31,PRKCA,RAB1A,GLO1,PTPN22,PDCD1LG2,SOCS3,FOLR2,TESK1,DVL2,BRD3,PGAM1,LRP6,RNF121,NFKBIB,MMP21,RAC2,STK24,TRAF2,RAB30,COTL1,BRCA1,RFC4,APEX1,NR1I2,GAB1,AKT2,PFDN4,FKBP1A,NPR2,CDK4,DUSP19,PPP4C,NME1,RNF5,NRBF2,RGS2,BCL10,NOS1AP,DNAJB2,PDHA1,SMARCB1,SERINC3,KLK6,DNAJC3,ENC1,PLCXD3,MMP20,TSN,FOXP1,SLC4A10,TRIM6,STAU1,PLA2G12A,CDC42EP3,MCM3,RAB33B,TOP2B,RGS19,BAD,RCE1,TRIM54,PRPS1,OR5V1,RASGRP3,PDCD4,CREBBP,VAPB,PDCD10,RAB3D,HERC3,EEF1E1,GIT2,NKIRAS1,PTGER2,MYC,RUVBL1,PPP1R8,ZMAT3,RAB35,KDM4B,SERPINA3,RASSF4,CLK1,TRAF1,SYK,ACO2,PIK3R3,MAP3K11,TRIM62,AHSA1,PLEKHF1,GNG2,DUSP10,CDC42,TERT,IDH1,NCK1,IL2RG,GNG13,STRADB,RASL10A,SIAH1,PSEN2,SRC,SNX1,AKAP14,NMRAL1,FAM162A,AKAP1,CCNB1,METTL2A,NLRP6,PSMA6,UHMK1,HMGN4,NLGN1,PTGER4,TRAF3IP2,CDKN1B,PIP5K1A,ERH,COX7B2,POLE4,MET,FZD6,HSP90AB1,GPHN,SFRP4,HELT,CRADD,PPP1R3C,SNX11,SERPINB9,CSRNP1,UBE2V1,S1PR4,PADI2,RPL22,CYTH2,RNF11,GNG5,RHOU,CCR2,WDR82,DSTYK,HMG20A,DNAJC2,IPO8,GNB1L,IFRD1,ACSS2,RANBP1,ATF3,RANBP6,CXCL12,SERPINI1,IDO1,PPM1D,BIRC5,FGF23,SFRP1,ELF1,LDB1,F9,PGPEP1,ENO2,PSENEN,TNFSF13,TOP1,UBE2H,CAMKV,ARL5B,SNX17,RALB,GMNN,DNAJC22,ARHGAP25,FKBP2,BCL7B,KDM1A,DDX1,RNF40,SNRPA1,ABHD2,TP53I3,ASB8,DDR1,INPP5E,SPSB3,GNB1,CASK,CDC16,SAP18,LTBR,TRIM23,IRF1,CUL2,PIAS1,PYCARD,SOCS4,CCNH,HSPD1,UBE2A,POLA2,MED30,POLB,CCT2,GHR,UBE2D3,CXCL11,GADD45A,PPP5C,APOBEC3A,ID4,CCR6,BTG3,FOXP3,LMO4,PIGA,ANAPC11,MAD2L1,PPP1R1A,CDK5R1,MSTN,MAP2K6,RNF148,RASGEF1C,STK4,PPP2R2C,TRIM46,NR1I3,DNAJC1,ITK,TRIM44,TNKS,SWAP70,MYL12A,SLC22A17,GNB3,JAKMIP1,HINFP,ITGB8,CTNNBL1,BTG2,IDH3B,VAV2,TIAM1,TRIM63,SENP5,PPP1R2,HSPB6,GNA11,HSPA5,SERPINB1,SRSF2,SNRK,SLC30A5,KLK3,SMARCD3,NKIRAS2,ACVR1C,MRPL50,PIP4K2C,STUB1,GNAI3,SFN,RAG1,ENY2,RING1,IP6K1,FBXO22,RFC3,CNP,TFG,RND3,PFDN5,COX10,FBXW4,SERPINC1,HLF,CDK8,WDR83,TRIP4,MDM2,MRPL13,SOCS5,AK2,POLE3,AKT1,NFKBIA,FGD2,IKBKB,RNF10,NCAPG2,ETF1,MSH6,RAP2A,HRAS,PPP1R11,RAB11A,KLF4,COPS7B,DENND2D,TRIM8,DKK3,RNF34,LIG3,PRKCQ,ARFGEF1,PGM1,CD40,IKZF2,TNFSF15,TRIM3,RAB6A,USP16,FKBPL,SIN3A,CDK7,TNFSF8,PTPN11,NOTCH2,SOX3,FBXL4,ZMPSTE24,FBP2,RSPH1,MAP3K12,E2F6,DTWD1,TRIM32,ASTN1,RPA2,NFE2,CCR1,PRIM2,FAF1,KLK9,ALKBH2,DOK4,ARHGAP1,NCKIPSD,TAB2,SRPK2,RNF141,TP53INP1,TRAF3IP3,IGF1R,PPP3CA,NME2,CX3CR1,SHC1,DIRAS2,NR4A2,ARHGAP12,FGFR1,UBP1,STARD4,SATB1,ORC6,SCFD1,NR2E1,DROSHA,PSEN1,MCM4,PCK2,CAMK2G,SRP54,EDA2R,ACO1,FKBP1B,LMO2,FAM177A1,RAB18,FKBP14,INSM2,IDH2,SIAH2,AGER,CER1,SUCLG2,FCGR2B,DUSP3,RAB31,DYRK1A,BIRC2,MTM1,TRIM27,TYMS,COPS2,AGK,SCML1,FBXO32,UMPS,ANAPC2,RUNX1,GJC1,EIF2AK2,SS18,PPARG,CNOT2,CAMK1,SNX2,SPRY1,ERAS,PLEKHO1,MYBL2,TRIM21,SCML2,SEC63,DNAJC19,RBBP7,RMND5B,NOVA1,ROCK2,PTTG1,PTPN1,TRIM37,ELF5,HECW1,TRAF6,SP1,MDC1,ARHGEF6,MGMT,ASB7,PRKACB,GLRX2,TADA3,TRAM1,HEY2,FRMD8,IMPA2,USP2,ZDHHC14,FEN1,ADRB1,MCM8,RIT1,FAM3C,PTP4A2,PTPN4,SERPINB10,TPM3,SNRPB,FBXO42,AR,ADCK1,WSB1,TOPORS,LYZ,NLRP9,DLAT,FZD4,FXN,RNF8,PEA15,GRAP,RAB3B,ADAMTS10,UBE2G2,EP300,JAK1,BAG2,EIF4A2,OTX2,MLF1,COPS5,STAT5A,TRIM26,CYTH4,MED17,PLCB2,MAP2K1,APOBEC3F,FKBP8,GABPA,PPP2CB,LMNA,PHF1,KIT,RASL12,SMAD1,RNF41,RXRG,TTL,CCR7,TMEM74,CTNNBIP1,GNG7,KPNA1,TIMP3,CSNK2A1,GMPS,RARRES2,PPP3R2,MPG,DNAJC5,TGFBR2,FASLG,TANK,TNFRSF1B,JUP,EXT1,VRK1,PGK1,DMPK,EIF3E,USP3,CDC23,RABGGTB,FBXO7,MMP9,GNGT2,BUB3,CTTN,ZMYM2,CFL2,RPL23,SNX5,PARP2,EPHA2,NLE1,NF2,HSPA13,SESTD1,PPP2R5E,MAPRE2,FOXA3,DAAM1,CCR4,ITGA2,KLF3,COX6B1,SERPINA1,SRSF1,SUMO2,XPOT,CXCL1,TNF,RHOBTB3,DDX46,SUMO1,HSPB1,OCRL,UBE2E2,KDM2A,POLD2,RPS6KA4,RAB4A,ELK3,DPH3,DHX16,CD81,DCLRE1C,PRKCE,PIK3R1,TSPAN17,GRAP2,RAB27A,COX6B2,RNF133,SERPINH1,FBXL14,RHEB,HSPE1,GNAO1,XRCC5,TIMP4,COPS4,SNX22,KCNK17,CDC20,NBN,LMBR1L,CBL,IL2,IRAK4,WDR11,NHEJ1,GAS8,CDKL2,FBXO8,FBXO30,WWP2,RAP1A,MMP14,RAB6B,CDC7,ST6GAL1,RASGRP2,ST13,TRIM45,SRSF7,MDH1,DUSP21,ELK1,SAV1,STAT2,RAB28,SGMS1,CXCR1,NEDD8,CBLL1,RBBP8,MRAS,UBA3,HDAC5,USP6NL,SNX10,HECTD3,DNAL4,NR2F6,HERC4,DKK1,PRCC,BCL6,GAPDH,RBM22,RRM1,KRAS,GSK3A,YES1,OXSR1,ORC5,DLST,VAC14,BAG3,LDHA,E4F1,RASD1,NLRP3,CBX3,RND2,PPP1R1B,BCL9,BMPR2,APOBEC3C,RNF103,IER2,XPO5,MED13L,XPO1,EXOC2,IDH3A,RFC5,THRAP3,DAPK3,COCH,RAPGEF5,PICK1,NTRK3,PHKG1,TSSK1B,NUF2,COX6C,PICALM,NEK7,CIRBP,CRTC2,BAX,RNF146,SAP30L,NEK9,FMO3,TNFSF10,CDK5RAP3,FURIN,CDH11,PIK3CA,CHIC2,FBXO3,AGAP2,APEX2,SF3B1,UBE2B,CSE1L,FBXL19,BCL2L1,FBXW7,IFT57,CDK12,ANP32B,ACVR1,DUSP1,PSMD10,BATF,TNNI3K,PPP1CC,NFYA,ARL4D,DMAP1,RAB3C,MTAP,TNFRSF9,EPHA4,ARHGAP21,RHCG,MCM6,ADH1A,BMPR1A,GNAZ,KLF10,DIRAS1,DNAJB9,RNF144B,PLCB1,CASP4,APOBEC3G,FBXO9,COX7A1,NTRK2,GNG12,CCND1,NR0B1,USP15,SPOP,CCNA2,UAP1,ENTPD4,RLIM,MCPH1,PTEN,ID1,SURF2,POU1F1,CYC1,BOK,TNR,RGS10,KIF2A,FBXL3,YWHAZ,INPPL1,ASB1,RBPJ,CXCL13,CXCL9,CKS2,RORB,DUSP9,AKR1A1,SHPRH,EGLN2,BPGM,CDKN3,SDHB,PCGF6,DEK,CXCR3,PRKD3,NUP107,RNF152,ETV6,RABIF,BCL7C,SIRT7,FBXW11,DUOXA2,MTMR12,TRAF7,NINJ1,CDC5L,TNFAIP3,TRIM34,RGL2,ITGB5,PPFIA2,RAP2B,PTK7,DHX38,COX8A,NCOA5,HUWE1,CPLX2,USP8,RUVBL2,IGF2BP1,CSNK1G3,RAB39B,SNX3,SIKE1,NONO,PITPNB,POLL,USP46,SMAD2,RAD1,UBE2L3,GNAQ,PMAIP1,SPRED1,NDUFS6,JAK2,USP38,NT5DC1,TRIM36,CBX7,USP39,CERK,SPRED2,DDX23,PCNA,PIK3R2,NAB1,IL5,VDR,FZD3,PTP4A3,RHOBTB1,PROX1,PRKX,TNKS2,CX3CL1,HSPB2,LSM6,PEBP1,STK3,SOCS2,UBE2N,CTNNB1,TRIM29,RAB8B,SMURF1,FKBP4,DKC1,FBXO44,PSKH1,SLC38A2,PLD3,CDK6,TAF2,SGMS2,NCSTN,ESR2,MCL1,PFDN1 |
| 1.973e-13 | -29.25 | IFI16 (interferon gamma inducible protein 16) | protein interactions | 3428 | 707 | 287 | 19454 | 5460 |
SURF6,CDC5L,DKC1,ADD1,SYNCRIP,USP15,RPL10A,AGPAT1,RPS2,SMCHD1,SNRNP70,E4F1,ELOC,CSNK2A1,PGAM1,KARS1,KPNA2,IMP4,HNRNPK,CDC40,NUP107,DHX9,RPL3,MAP1B,PSMC3,RBM34,CBX3,RP9,H2AX,IPO8,TP53,RPSA,RSL24D1,MACROH2A1,CSNK2B,LIG3,PSPC1,RPS3,IGF2BP1,TLR9,DNAJC10,RPL7A,MAT2A,RPF2,SMARCA5,MARS1,HSPA5,ZC3H15,STK38,WDR3,DLAT,LSM12,EXOSC4,PML,NLE1,UTP15,SDCBP,SNRNP27,GTF3C4,CDC42,SUMO1,TRMT61A,PEG10,TCP1,LYAR,SNRPA1,ISG20L2,HNRNPL,S100A8,MAGED2,SRSF1,DRG1,DDX1,FKBP4,UTP6,NGDN,YWHAG,RPL6,RIOX2,IFI16,BAZ1B,DDX50,POLDIP3,PAEP,TFG,RPS4X,HNRNPF,PDIA6,RUVBL2,TRIM21,TOP2B,CCT8,PABPC1,ABCF1,PDHA1,GLE1,PLS3,EEF2,NUP37,H1-3,DHX38,SUPT5H,RANBP1,TRMT1L,RPL10,ACAP2,POLR2B,CBX5,MATR3,ATP5F1B,PRMT5,SMU1,RCL1,POLR1B,ZMPSTE24,NSA2,ICAM1,FTSJ3,H1-10,FBXW11,BTF3,HNRNPAB,PSMA4,APOBEC3B,MYC,SAP18,STAU1,FXR2,EP300,DDX5,SF3B1,HSPA8,XRCC5,EIF4B,NUFIP2,ZC3H14,NUP62,MDM2,TOP1,CGAS,PWP2,KRR1,HACD3,OSBPL8,ID1,MPHOSPH10,SPATS2L,MOV10,GRSF1,PRDX4,MDC1,MSH6,CTNND1,NOC4L,PAK1IP1,HUWE1,NKRF,SRP72,ILF2,LLPH,RPL15,FCF1,EXOSC8,DDX39A,CCT5,FBP1,VIRMA,PNP,TMOD3,RAB14,SPIN3,PRKRA,EIF2AK2,ENO1,TUBA1B,PELP1,IVNS1ABP,RACGAP1,AR,ATP5F1A,SEC13,CTSD,CSK,AATF,BRIX1,TMEM209,NHP2,FBXW7,RPL4,MTDH,SQSTM1,PNO1,PPM1G,MACROH2A2,WTAP,RPLP0,ZNF574,HSP90B1,CDK1,UBA52,SF3A1,PSMC4,STK3,DHX15,NUP35,CACYBP,SPTAN1,RPL7,CCAR2,ATXN10,NOP58,HP1BP3,PHB1,MRTO4,IFIT2,PPP2CB,RPL8,PDAP1,HNRNPD,RSBN1L,PPM1B,TRAF6,SKIC8,CSTA,DDX23,WDR12,HNRNPA1,PRPF19,PSMD3,RFC3,SSRP1,PCGF6,RFC2,PSMD12,SRSF4,MCM6,GTF3C3,TRIM26,DHX16,G3BP1,PRPSAP1,JAK1,PPAN,HSPD1,NUDT5,SLC25A5,SART3,EXOSC3,CHMP4C,JUN,MAK16,NUP153,ASPM,PPP2R1A,FEN1,B3GNT2,PRRC2A,RBBP4,TUBB,RPF1,DYNLL1,TAB1,ACTB,EIF3K,PELO,TRMT6,HSP90AA1,SP1,BRCA1,YWHAZ,MCM4,RNF40,PRPF31,PYCARD,NOP16,G3BP2,COIL,RADX,NOP53,NUP50,EMG1,CCDC86,UPF3B,LARP4B,APOBEC3C,USP39,WDR77 |
| 2.017e-13 | -29.23 | RHO | smart domains | SM00174 | 123 | 71 | 9717 | 2575 |
RALA,RASL11A,RAB2A,RAB31,RAB40AL,RAP2A,RASL12,RERG,RASL10A,RHEB,RAB30,RAB18,RAB33B,RAB1B,RAB23,RAB11A,KRAS,RHOJ,RAP2B,RAN,RAB13,RHOU,RAB1A,RAB39B,DIRAS1,MRAS,RND2,RAB9B,RAB6A,RAB3D,RAP2C,CDC42,RAP1A,RAB22A,RAB33A,RAB5C,DIRAS2,RHOH,RABL2B,DIRAS3,RAC2,RND3,RAB27A,RAB29,RAB4A,RIT2,RAB14,RRAS2,RAB6B,RAB3A,RIT1,RALB,ERAS,RAB37,RAB5A,RAB9A,RHOG,RAB3B,RAB8B,RAB11B,RHOB,DNAJC27,RAP1B,RAB35,RASD1,HRAS,RHOBTB1,RAB28,RAB3C,RAB32,RAB19 |
| 2.049e-13 | -29.22 | cellular metabolic process | biological process | GO:0044237 | 5975 | 1972 | 18204 | 5365 |
IRF8,HSPA14,DRG1,VIPAS39,SNRK,EIF4EBP2,FKBP1A,CTTNBP2NL,XXYLT1,PELO,DNPH1,PRPF19,DHX15,CTSB,NR1I2,PPTC7,CDC5L,IMP4,CWC15,RBM23,MVD,DNAJC25,QTRT2,MTRF1,CYP1A1,LSM8,HNRNPA0,CPEB1,CSNK2A1,AZIN1,CPSF4,PTPN5,DHRS7B,VTA1,SART3,SOX9,ERO1A,PPIG,BAG3,AANAT,SUGP1,SLC2A3,LSM2,RPRD1B,SMNDC1,LTO1,GFM1,CHST9,DPEP1,ST6GALNAC3,MAP2K3,DUSP3,MAT2A,STAT6,RNF8,SF3A1,THOC3,ADRB2,DDX4,ZNHIT6,SRSF7,C9orf72,PRDM4,FKBP2,CHRAC1,LDHA,DBR1,GLRX2,OLA1,RPP25L,VAMP8,RAB1B,CMA1,SWAP70,RUVBL2,GSTA2,NEU1,YAE1,SLC25A17,TRMO,GPBP1L1,CSNK1G3,RPL17,F9,PDP2,FAM98A,FXN,ATP5PO,DGCR8,RPL37A,CDC37L1,PAAF1,THAP1,NDUFC2,IL4,GTF2H4,ALDH1L1,PPP2R5E,MTMR6,DUSP19,SOCS2,AGO1,CRYAB,SECISBP2L,SREK1IP1,RGS19,DYRK2,HACD2,DDX42,TLR3,RPS14,ACADSB,UST,MAP3K12,PDE7A,STK3,GDE1,NXT1,MIF,NDUFS8,PCSK2,SOD3,EIF5A2,REN,TAFAZZIN,ILK,CASP4,RPL6,FDFT1,CD2BP2,GGT7,MED4,TOP1,LSM3,SUPT5H,CDKN1A,MPST,LRAT,FUT8,NHEJ1,ABCF1,CASC3,CSNK2B,CHST7,GGCX,H2AB1,PDHA1,PPM1D,RP2,BOLA3,NLRP3,NEK9,RDH12,TEX12,PHB1,CYP17A1,PPT1,DUSP18,PCLAF,DUSP10,GTF2A2,CCT8,CYP4F12,CYP3A5,DNAJC10,STUB1,CDK5,CERK,RPL28,RSL24D1,PLAC8,ZNF326,CYP2C18,PIWIL1,HEXB,FAR2,DROSHA,METAP2,WDR6,CDC123,LGALS3,SDHAF4,CYP27B1,RETREG1,RBM3,CHMP4C,UFL1,RBM15B,TRMT61A,PPP2R3A,CDKN1B,TRA2A,FYTTD1,SLC25A12,CAMKV,B4GALT3,DDX46,NAA35,POR,RPL35,DDX5,NCBP2,FADS2,TRMT13,HENMT1,UBIAD1,MAP1S,SPCS3,TP53,PYGM,UQCRH,RBMX2,ST3GAL4,USP39,CYB5B,MRPS11,IFI6,RARS1,SORD,ZNF473,RPL9,ZNHIT3,HSPA8,PPIB,BAG2,INTS10,SCD5,PTPN1,GLCE,PRKCE,ATP5MC1,B3GALT2,SRFBP1,DIO2,PARL,SMU1,DCK,TAF11,RPL4,PIP5K1A,CKB,PPP3R2,PCSK9,ACP5,B4GALT1,IL2,PAK2,CYTL1,PAIP2,HIRA,SNAPC5,AR,MRPL52,SOD1,PFDN4,DOLK,TERC,XBP1,PNPO,RPL27,RPL13A,EHHADH,PID1,SLCO1B3,VDR,DUSP14,BAK1,B4GAT1,PRPS1,DIO3,CLK4,SIRT7,ASPA,PIP4P2,COX6A2,FUBP3,RPS4X,HACD4,ACO1,DUSP26,FKRP,GPC1,CCT7,PDRG1,RPL26,CEBPE,CA10,BMP1,PNPLA8,CHMP2B,RPL7A,OPTN,PRKAG1,TUFM,NUS1,SLC35C1,TP53INP2,RIGI,UQCRC2,PAX6,GFPT1,URM1,CRYZ,WNT10B,DNAJB6,MDH1,AQP11,RIMKLB,HM13,RAMAC,TNIK,B3GALNT1,HDAC3,ATG7,TKTL1,MTAP,NDST1,AHCYL1,UTP6,EIF4E,TP53INP1,DDX39B,PADI2,CHMP1A,UQCRC1,CDIPT,PTP4A3,POP5,THOC6,IMMP2L,POLD4,MMP14,ABHD4,SNAP29,CLIP3,RPL12,GNPNAT1,DUS4L,GPD2,TENT4A,PPP1R12A,PPP2CB,DRAM1,AGPAT5,FOXP3,RCL1,AKT3,CA2,SLC16A10,CCL2,GLRX5,PHF23,DUSP6,GCFC2,RPL10A,NPPC,PDE2A,DNAJC1,KIN,EIF5B,RBM42,VPS54,TRMT10B,RPL7L1,DPP4,CDK4,TBK1,APOBEC3A,DMPK,C1D,PRPF31,TBCEL,MRPS25,G6PD,RARRES2,ABHD16B,MED9,GPAM,TRMT112,FA2H,CNOT6L,RAB33B,RAB33A,MED23,VSIR,APEH,LGALS8,RBM17,CERS2,ZDHHC17,TESC,S100A8,EAF2,PRDX6,ZC3H11A,SELENOT,TRIM5,PPIC,APOBEC3C,MAK16,SYK,PCYT1B,HNRNPL,VRK1,CLK1,MGST3,GTF3C4,PPM1K,SAMHD1,RPS11,UNC45A,ALPL,RRM1,PPM1B,FGF23,CYP4V2,EIF3E,NUDT16,CAPN2,DEK,HS2ST1,ELOVL4,STT3A,PTDSS1,CDC40,CAMK1,NDUFB8,ST3GAL5,PIK3R2,VKORC1L1,AGK,YWHAZ,PRKACB,CTNNBL1,SUPT4H1,GPIHBP1,THOC1,ROCK1,GFM2,CYP39A1,RPS10,F7,PIK3CA,TAF10,ATP5PB,NMRK1,ELOVL3,APEX1,CHST13,MAP3K21,UTP25,RPL35A,BACE1,ACO2,HSD17B8,CD40LG,UGT2A3,RNF41,PDE4B,FAHD1,RBM41,TFEB,RB1CC1,CHTOP,PRDX1,WDR3,PRKCB,CTBP1,AHSA1,MCHR1,SNRPE,SNRPA1,PFDN2,MACROH2A1,ATP1B1,HYCC2,MRPL36,CISD1,P4HA2,ETNK2,CDK7,NDUFA2,PRCP,GPX4,BAZ1B,CWF19L1,MTARC2,TECR,PCNA,SNAPC1,ATP5F1B,NAT2,CPT1B,TCEANC2,POLB,SNRPD3,PLSCR3,SRPK2,PAK6,METAP1,DTWD1,PIWIL2,RP9,RTCB,VPS4B,PDHB,FARSA,FUNDC1,ADTRP,NFKBIB,PDE8A,GAL3ST1,PTPN22,USP13,NDUFA1,QNG1,NPM3,TTC4,PEX13,PXYLP1,EIF3J,ABHD14B,FMO1,PTPRZ1,CD28,TAX1BP1,CBFB,HSP90AB1,FKBP1B,CMAS,LDHB,SMPD2,CAV3,OXCT1,PFDN6,ATP6V1A,SLC20A1,CRAT,FCF1,SMG5,DCTPP1,MRPS33,WBP11,YBEY,POLR2I,SNRPA,ARB2A,RPS27L,ATG9A,PPP1R2,EGR2,ARL6IP5,PLPP6,ZCRB1,NUDT5,ZMPSTE24,ABHD12,TAF2,CREB1,IER3,SELENOF,G6PC3,SCNM1,TDRD7,PTGES,PRDX3,SLU7,HSPB2,DNAJC30,SPON1,DNAJC19,FMO2,HNRNPA1,WWP2,PMPCA,GLO1,THOC2,NUDT18,MRPL16,HSP90AA1,USP15,EIF2S2,POLR3GL,NDUFA12,SOCS4,DAD1,WDR45,CYP2F1,CDK5R1,MBLAC2,OST4,INPP5K,HTR2A,SPCS1,FBXW11,H2AX,OGG1,QRSL1,ANKH,RPF2,ATG3,PPAN,SPHK2,BOLA2B,SLC29A1,ACOT8,UFM1,RPS28,DDR1,KTI12,SCN2B,MTRES1,DIS3L,LDB1,STK38L,AIPL1,RPS16,SNX14,RPS3,EEF2,ETF1,PLAAT3,ADIPOQ,GALNT2,ROCK2,CAB39,S100A10,MAPK10,DPAGT1,PRPF4,BATF,BRIX1,MME,RPS29,PIR,EPHA2,MTMR12,RDH11,RPS5,PYCR1,EDEM3,MRPL47,PLAAT5,PCYOX1L,OSBPL8,AASDHPPT,ATP5F1E,AK3,ITK,GNPDA2,LSM6,POLR2L,CLN8,COX5A,MYRF,PLPPR1,GAPDH,ACOX1,LIPA,CYP7A1,TAMM41,RPL23,RAB39B,NUDT7,CCNA2,FUNDC2,CSNK1A1,GLE1,STK24,PDE9A,TSPO,KDSR,GNPDA1,STX12,ZMAT5,IL21,PEDS1,VPS72,ACBD7,FHIT,VPS4A,TAF7,GNPTG,PFDN1,SPPL3,HADHA,IDO1,PTPN11,POLR1B,CCL11,SELENOP,TSEN54,MRPS18A,FKBP10,DHRS3,SEC11A,CYB561,EVA1A,UGDH,NONO,CDK6,NDUFAB1,HELT,PTPRQ,FGFR1,MTHFD2L,ATXN1L,GGTA1,ACSS2,PIWIL4,SPTSSA,GSK3A,EIF3G,ADCY2,KPNA6,AKR1A1,B4GALT7,BAD,CDKL2,CHPF,TSPAN15,PLAA,CDK12,GAMT,CTDSP1,GYS1,ATG4C,RIC3,TRIM24,NRBF2,ADRB3,MMACHC,CTSK,SLC1A2,NPR2,CRTAP,RPF1,GPX1,ANXA7,TMEM106A,RFC3,UQCC3,EP300,GEMIN8,HSD17B10,CRYL1,WDR77,RPN1,PIK3R3,CSTF3,GABARAP,PRMT5,GRB10,ISG20,SDHAF2,UBXN6,MRPS34,CDC7,DPH3,LMNA,GON7,MRPS35,AKAP17A,RPL26L1,MPHOSPH10,POLR3F,SNAPIN,H3C1,RMND1,RPLP0,LYAR,SNAPC3,ELK1,CHMP2A,PHYH,EIF4E3,SLC25A42,ENPEP,HADH,RBFOX3,INHA,MRPL22,ECRG4,COX6C,METTL2A,RWDD1,ESS2,ABCC2,TIA1,MFN1,BGLAP,STOML2,ASMT,SNRPB2,RNF14,POLR3B,DUOXA2,SULT1B1,IMPA2,MRPL11,GNMT,LUC7L3,PRELP,THUMPD1,SLC1A3,OSGEPL1,UPRT,VPS33A,MORC2,MAT2B,PNP,VDAC1,MRPS7,HSPD1,THTPA,KCNJ8,NFKB1,TESK1,ARG2,B3GNT2,MGAT4A,LIPT2,P3H1,SUPT3H,PLP1,PRSS12,FOS,CLPX,PRSS37,PHKA1,MRPL18,RPAP2,CYP2C9,SLC25A44,HNRNPF,TXNL4A,TMEM59,RAB19,ACAT1,TRIB1,THBD,NUDT12,GSTM4,TTC1,TRAF6,CHKB,SELENOI,EIF4A3,SNRPN,TAF9,HNRNPD,SELENOK,NXT2,ATG16L1,SLC7A11,CMTR1,GPAA1,DUSP22,TRMT1L,SMAD3,ELP3,DNAJC4,NDUFA5,AKR1B1,SNRNP27,FNTB,TYW3,GFUS,ZDHHC4,UQCR11,PPAT,WDR83,ADGRG1,BMPR2,LYPLA1,CELF6,EXOSC3,MRPL50,AKR1C1,COX6B2,MECP2,AKR7A2,ETFB,B4GALT4,UBL5,CCT5,DDAH2,NTRK2,ASNSD1,GSTK1,TFIP11,RPS24,IFI16,PGK1,TLCD3B,METTL14,NBN,HS3ST3A1,KRR1,CA12,COX7B2,TMEM208,MAN1A2,PIGK,UTP15,C1GALT1C1,FAH,SLC30A5,IRF1,SLC25A32,PQBP1,DNAJC5,STYK1,MRPL53,MEF2A,PRKRA,PGM1,HBA1,TOM1,DHX38,USP30,DLST,NUDT4,DTL,RPL8,BIRC5,TENT2,ZRANB2,RBM27,FAU,CHPF2,ATP5MC3,ISCA2,METTL6,PLCB2,PSEN2,CHDH,AIG1,HNRNPK,IDH2,SF3B6,MGAT4B,ATF4,NOVA1,POLR2F,NRDE2,MTMR2,SRGN,PTGES3,EXT1,GXYLT2,ANGPT1,PPID,PPIL3,SRC,CDK20,CCS,SLC19A3,HGS,PPP1CC,MAP2K1,MAP3K14,CTU1,TSN,BUD23,RIMKLA,TLR7,NHP2,GAD2,POLA2,HBB,COX4I1,FIS1,DICER1,GXYLT1,BECN1,TOPORS,TNNI3K,DLG1,CHST11,SLC25A14,SF3B5,EXOSC4,RGN,SUB1,RPL7,HCST,IL1R2,NSA2,ALG11,MRPS17,PDF,LTB,ZMAT2,TRMT5,PGAP2,EIF2B3,RPL29,LIAS,HYCC1,PDE1A,RPIA,ATP5MG,OSBP,DHRS7,GTF2B,CCR6,UAP1,GALNT4,ZNF345,SULT1A3,COL3A1,GDPD3,CA8,FAM20C,PLA2G15,DHX9,SDF2L1,SEPHS1,AMACR,MRPS16,RPS9,GSTA4,VTI1B,ALG5,EEF1E1,FASTKD5,THG1L,AK2,SNRNP48,FURIN,RPL18,SSH3,RPL10L,SLC6A8,MRPL57,IGFBP3,EPHX1,LSM10,CYP4F22,SLC25A51,HSPA5,SOCS5,KLHL3,HTRA2,TAF5L,MYD88,IGF1R,RTRAF,ARMC7,CSNK1E,IFT172,RCHY1,AUH,PGAP3,PLA2G4B,GGH,ABHD10,PPIA,PTP4A2,TUSC3,ZDHHC15,PELP1,GBE1,EPHA4,MMUT,TSSC4,NDUFB7,BARX2,IL6ST,GTF2F2,OSGEP,SRSF12,ATP5F1A,PMM2,MAP1LC3B,PRPF18,RB1,PTPMT1,ELOVL1,IK,CYP11B1,RSRC1,TYMS,NFYA,FOLR1,SDR16C5,DCTD,RBM5,CDK9,TMEM39A,MFAP1,RETREG2,SDHB,ALDH1A3,PYGB,MAPKAPK3,CTSD,GALNT12,CHST2,CEBPG,RBM38,CNTN1,SNRPD1,GTF3C3,SLC25A4,DIO1,CDK8,PDIA3,PDE12,GRPEL2,SHMT1,GALC,TNF,HMGA1,CYP11B2,SF3B1,COX4I2,FBP1,FITM1,MRPL34,HINFP,ABHD5,ITGB8,MED11,EPHB6,ATP5MK,SSU72,DDAH1,TOP2B,ORMDL3,BCKDK,NSFL1C,PFDN5,BCL6,B2M,GABARAPL1,GPHN,RPS26,TCEA2,GTF2I,PRIM2,EIF2B2,HINT1,HMCES,CBR3,PTPN4,GAPT,MLF1,SLC16A1,AOX1,GMPPB,RPL15,PAPSS2,CDO1,ALG2,BPNT2,PPWD1,NQO1,SNRNP40,CHMP5,MRPL10,IRAK4,TNFAIP8L3,PPP2R1A,GSTA1,SUV39H1,PPP1R1A,NDUFV2,MAP3K3,EPOP,FTSJ1,CNP,ZC3H7A,CSGALNACT1,NEK7,SOD2,PTAR1,LEPR,ACCS,DDX23,PIGC,MAEL,ST6GAL1,CIAO1,GNAI3,STK4,IP6K1,TOR1B,PIP4P1,INPP4A,SPTSSB,B3GALT1,KLF4,IMP3,RPS15,MPP1,TLR4,TSSK1B,POLR1H,TMEM165,SAP18,TMEM38B,CRABP2,TRIP4,EMG1,UGT1A1,GEMIN7,ITGAV,CHORDC1,GHR,LARGE1,DOHH,ACER3,SCPEP1,FN3KRP,EGLN2,SLC25A10,RPRD1A,TSG101,PPP5C,PLA2G5,FTSJ3,NR1H2,TGFBR2,TP53I3,MSH6,RPE,TOLLIP,MET,CPE,EIF4A2,COQ8A,CYB5R4,TSPAN5,KIT,SLCO2B1,GSTP1,TXN,NUDCD3,ATP5PD,INPP5E,MT3,SGMS1,UCP2,MRPL23,WTAP,ENY2,DKC1,ROMO1,APH1A,IGF1,SKIC8,CALR,ABCB1,CHCHD1,GRSF1,PCCB,UBA52,EXOSC8,METTL15,MTERF2,PFKFB2,EIF4B,SLAMF9,VPS39,DNAJC24,CLP1,PPP3CA,ACP2,ELAVL4,KBTBD2,ESD,IL1B,DYRK1B,AKT1,TAPBP,EXOSC1,PIGW,UCN,ACP6,VPS18,ASRGL1,NUDT19,DUSP21,GTF2A1,NCAPG2,MED27,DHRS4L1,REXO2,PAPOLA,ADSS2,GMDS,MAD2L2,EDNRA,DSTYK,RPL27A,OCRL,CDKN3,DHX16,B3GALT4,ST3GAL2,DNAJC3,CDC73,SRD5A3,RBM34,DNAJB2,LPCAT3,ADM2,ORMDL1,PLCB1,RPL10,PPP2R5A,MGST2,LAMP2,AGPAT1,IL6,HEXA,BAX,TRAF3IP2,GP9,NOP58,ADIPOR2,DEGS1,ADAT1,SEPHS2,PAIP1,LSM5,ACAA2,FBP2,ACSL4,ACVR1C,NKX3-2,CYP27A1,CHAC2,DNTT,RAB23,DDX1,TBC1D25,ZDHHC14,POLR2C,SUCLG2,SF3B4,OXSR1,DAPK3,SMN1,GPR137,COPS2,RPLP2,GGPS1,AKT2,HS3ST5,FUT1,DHPS,ERRFI1,DLAT,UHMK1,PIH1D1,PIGA,RDH10,CACNB4,ATP5F1D,EXTL2,HSD17B3,MGAT5B,MRTO4,MAP2K6,HPGDS,WBP2,NUP62,POLR2B,MAPKAPK5,UCK1,CSNK1A1L,AKAP8L,PICK1,YIPF5,PTHLH,PPIF,STAT5A,MECR,TRMT6,BPGM,DUSP9,CCNH,MRPL13,HBE1,GTDC1,MRPL12,SGMS2,PPM1M,MRPS9,FKBP4,CYP1B1,ST8SIA5,RPS13,TLR2,ENTPD4,VMP1,GLUL,MRPS18C,MRM2,STAR,EGLN3,SLC23A2,DUSP1,YES1,PRKAB1,NPC2,LHB,SLC2A1,MCAT,WEE2,TCEA1,UCKL1,XPO1,HDAC6,SGF29,MRPL17,DPM2,NOL7,INTS12,NME2,POLDIP2,FOXA3,CCAR2,MED22,STK11,GK2,ARFGEF1,TMBIM6,NOC4L,ACVR1B,MED10,MSMO1,SCG5,HMGCS1,RPL31,CMPK1,PRRT1,IL15,NDUFB4,HSPB6,RPS12,GTF2E1,ABHD2,RCE1,BCL9,FABP5,GTPBP2,PPM1G,MRPL41,AK5,STX17,NIBAN2,PIGY,SLC52A3,TCP1,TRUB1,CRYM,MRPL49,CDK17,SBK2,CUL3,RAN,PIK3R1,CCDC47,CPSF2,NDUFS6,LYPLA2,MAGOHB,GNPAT,DBT,WDR55,SERINC1,ADRM1,DECR2,WDR12,PAFAH1B1,FIG4,RBMS2,NUP107,NDUFS2,ADK,GMPS,ADH1B,TRMT11,ABCG2,RETSAT,COX11,INSIG2,PIK3CG,HNRNPA2B1,VAC14,NDUFB10,GTF2H2,CHST1,WRAP53,TOR2A,NT5C3A,MAP1LC3A,COX8A,FOSL2,IDH1,METTL25B,HNRNPC,COPS5,SMAD1,CCT2,ILVBL,KGD4,RETREG3,COIL,LDHAL6B,TST,HSPE1,ATP1A2,ATP5PF,AIP,MRPL9,PLA2G12A,MTF1,ETFRF1,TWNK,ACADS,DRG2,IL2RG,RPP21,NUDT2,CPT2,FBXL4,STBD1,DPY30,KRAS,GTF2H5,MRPL40,PPP1R3C,MPDU1,DDIT4,RBP2,ZDHHC24,CREBBP,PROX1,RPL22,SLC5A6,GCLC,DYRK1A,EIF2D,PGAM1,GSTM2,RAB1A,NME4,NDUFA4,NAA60,ODC1,PIM2,CDKN2D,ACOT6,POLR3H,RPP14,ST3GAL1,IDH3B,CAV1,SOCS3,PRDX4,MCOLN1,COQ8B,PPP1CB,MTG1,TAB1,TNKS,RBFOX2,NDST3,IDE,SNRNP70,SNRPG,APOBEC3F,MRPS23,MRPS21,PSEN1,MTM1,SLC19A2,RNF113A,DTYMK,MPHOSPH6,IRF9,CYP2D6,RBM22,BUD31,BRCA1,ALKBH5,LIX1,SMAD2,ACTMAP,TYW5,RPL23A,MARS1,SLC25A1,HSPB1,DAPK1,FITM2,CYP4F8,MRPS28,CASK,TPH2,GSTM3,COX7B,MRPS26,NFIL3,MED21,PWP2,CTDSP2,NAA50,GLYAT,ISYNA1,CYP26A1,RPS6KA4,SNIP1,CDK1,POLR2D,ATP6AP2,OAT,TRA2B,GPX3,GUCY1B1,STRADB,DAP,TFB1M,NUDT3,ECHDC1,EEF1B2,PGGT1B,TSEN34,FRA10AC1,GSTT2B,INPPL1,RABGGTB,ELOVL6,HSP90B1,CYC1,SH3GLB1,AMT,PPIH,RIMOC1,PIP4K2C,POMT2,CAPN1,HSD17B1,PLSCR1,TBC1D17,MTHFS,WDR83OS,LMAN1,PRKCA,TBC1D5,ACVR1,EIF4E2,CA14,AZIN2,RAB2A,MSX1,PPP1R1B,PRKX,VAMP7,ZC3H15,NAA15,POLDIP3,MAP3K11,DDRGK1,SRSF8,RAF1,SRSF2,GTPBP1,HNRNPH3,CD226,CARS1,PYCARD,HRAS,ZDHHC8,DFFA,HMGB1,H2BC1,VPS28,KLK6,EMC6,EIF4H,NCSTN,RPS20,ADCK1,EPO,PTGDS,MNAT1,NR4A2,MKKS,IKBKB,EGR1,PNPLA4,CHCHD4,POLE4,PPARG,ST8SIA4,B4GALT6,SPCS2,GSTO2,SDHC,GABARAPL2,GOLGA7B,SESN2,ADH1A,PRKCQ,HDHD5,SLA2,COX10,CYGB,PGAP4,ATG101,ABCC5,CHST10,NOP9,FKBP8,ERCC3,DDIT3,POLE3,ENO2,DNAJC2,COMT,PSENEN,TBCE,PRDX2,SRSF1,PLPP4,CMTR2,RRP7A,CHMP1B,GSTM5,HBM,POLR1D,TUBA1A,ACACA,ABCE1,UGCG,PTEN,JAK2,MED31,DDX39A,INTS6L,GALNT17,TSR2,STK26,ATP5IF1,TM9SF1,CYP2C8,RRN3,RIOK2,MRPS18B,POLL,EIF2AK2,SHLD1,SLC1A1,CTNNB1,CYP2R1,CYFIP2,TSNAX,GPT,MAGOH,CERS6,DR1,RPSA,GK5,KARS1,CAMK2G,POP7,COQ10B,PRKD3,NAA16,EIF3D,RPS27A,LSM4,PDIA2,MAPK4,SMAD4,NOP53,PYCR2,CD36,PMAIP1,BAP1,RPLP1,IREB2,NDUFS3,SRSF10,HYPK,LIG3,RPS23,MED29,KHDC4,ADCY3,HSPA13,PC,ELOVL7,ENTPD3,DCAKD,WDR82,ELP6,UQCRQ,DHRS4,PHKG1,EEF1G,RPS2,COX7A1,PSKH1,ECD,ETFA,SMURF1,DNM2,SLCO1A2,PCK2,CREBL2,GUK1,JAK1,HACD3,OGDHL,SYNCRIP,NGDN,PRPSAP1,CSK,ABHD6,GTF2F1,NANP,NDUFB6,ERP29,COX6B1,VIRMA,NIM1K,THRAP3,IDH3A,RPS17,FGR,RNASEL,EEF1A1,GAL3ST4,PAK5,RPL39,UCK2,ST13,PPARA,HAS3,AURKAIP1,ENO1,LDLR,GTF2E2,TERT,HS3ST1,RPL24,EIF2S1,FUT9,NDUFB5,ALOX5AP,MRPL20,UBXN2B,MRPL33,PABPC1,UGP2,RPL32,GSTT1,TFCP2,BMPR1B,NUDT9,SNRPD2,PML,CBR4,TMEM74,SFTPD,GRM2,UTP23,UMPS,TSR3,TPST1,ZDHHC16,MRPL24,FAM20B,DNAJC7,FMO3,CD38,CD2AP,NEK2,FKTN,DNLZ,NDP,VPS16,UBLCP1,NAA11,CSGALNACT2,POLD2,ELOC,TEX264,SARM1,ATG4A,NT5C2,PCBD1,EIF1AX,HSD17B6,PKNOX1,RPS7,STK38,ADIPOR1,GRPEL1,CLU,RPL3,MED30,SDS,CISH,RPL19,EI24,SLC38A1,TRAPPC4,DRAP1,SRSF4,SMUG1,UBASH3B,PDIA6,NFE2L2,DNAJB4,FBXO7,GCNT3,HNMT,COX17,PRMT6,AKR1C2,SMARCB1,NOB1,IVNS1ABP,HACD1,SFXN1,GOLGA7,SACM1L,BMPR1A,SNAPC2,NTRK3,EIF2B5,RPP25,PGS1,MGAT1,EIF3K,EIF1AD,GTF2IRD1,ALYREF,GSTO1,PHKB,DTWD2,ELOF1,TESK2,STK16,CPSF1,MED17,GALNT1,SERINC3,MRPL51,PHB2,TCOF1,LEP,SQSTM1,POLR2G,SNRPB,CMBL,NME1,SLC25A21,PDSS2,CSTF2T,SERPINH1,PIWIL3,SMARCA5,EIF1B |
| 2.070e-13 | -29.21 | ARAF (A-Raf proto-oncogene, serine/threonine kinase) | protein interactions | 369 | 372 | 170 | 19454 | 5460 |
HSP90B1,SSR1,CDK1,P3H1,RPA2,JUP,HECTD1,E2F6,HNRNPH3,RPLP0,UBA52,EEF1E1,ATG16L1,RPS14,NTPCR,KDM1A,IRF7,NF2,CLU,HSPA5,MARS1,MAIP1,DVL2,RPA3,H2BC12,CCDC22,CHCHD4,CALU,UBE2H,XPOT,STK11,EPHA2,IGF2BP1,TRIM32,AKT1,SLC25A1,NONO,TUFM,RPL22,UBB,TECR,ENO1,CTNNA1,STUB1,CCNF,CSNK2B,CALML5,NDUFS3,PIK3CA,CAMK1,ILF2,CDK4,IPO8,TP53,KBTBD4,MAP2K3,EEF1A1,THRAP3,PTGES3,FKBP8,RPL17,RPS13,TCOF1,TRAFD1,DHX9,RPL23A,BECN1,RPL24,NME2,CRBN,RPL10A,TESK1,ELOC,RPS27L,TOP1,SPPL3,CDK9,EEF1AKMT3,ACTA2,ALYREF,AIP,HRAS,HACD3,AIFM1,RPL12,TES,CDK6,MAP2K1,AGTRAP,PGRMC1,TIRAP,EEF1G,HNRNPA0,XRCC5,ATP5MK,DDX5,P4HA2,HSPA8,YWHAZ,CIRBP,LAMTOR1,CCT2,DNAJB6,HSP90AA1,RAB11A,CUL3,SFN,MYC,KDSR,RPL39,ACTB,PSMD6,DYNLL1,FBXO22,TUBB,ATP5F1B,RPL10,MAD2L1,RAN,BAD,PHF21A,RPS9,RRAS2,NME1,TUBB4B,KLHL12,RPS11,RAF1,RPS7,EEF2,TUBA1A,RPL29,PPP2R1A,FAF2,RUVBL1,KRAS,HNRNPF,RBBP7,RPL28,RPS27A,RPS4X,CCT8,PABPC1,SLC25A5,HSPD1,BAG2,EWSR1,TRIM21,RABGGTB,FKBP4,YWHAB,RPL23,HSPB1,HAX1,HNRNPD,RPL6,PSMD3,PIK3R1,PRDX1,UBXN6,YWHAG,XPO1,HNRNPA1,YWHAH,DYNC1I2,TCP1,RPL7,CCT7,HSP90AB1,EGLN3 |
| 2.077e-13 | -29.20 | negative regulation of programmed cell death | biological process | GO:0043069 | 946 | 381 | 18204 | 5365 |
PARL,SYVN1,TMEM215,AKR1A1,LRP6,NRP1,STXBP1,LIMS2,JAK2,BCL2L1,AR,RRN3,SOD1,IL2,MIRLET7B,PAK2,MIR221,CCND1,TSC22D3,PSMG2,CAAP1,MTRNR2L3,GNAI2,KIT,EIF2AK2,FAS,MET,XBP1,AATF,GPX1,MT3,GSTP1,BAK1,SLC1A1,TNFAIP3,CTNNB1,BOK,NAA16,PIK3R3,UCP2,PDCD10,VDAC2,PTRH2,IGF1,SELENOS,SLC25A31,IL1B,SIAH2,TGFB3,NDNF,AKT1,WNT7A,MIR182,LMNA,ZMYND11,NDUFS3,HHIP,HYPK,TPT1,ANXA4,UCN,MIR210,DSTYK,SERPINB9,BCL2A1,SIN3A,DNAJC3,PPP1R10,CDC73,MIR30B,MIR21,SFN,DNAJB6,MSX2,MCL1,RPL10,UBE2B,MAEA,GPRASP3,HDAC3,MMP9,ACAA2,IL6,STAMBP,BAX,MIR223,PEA15,NKX3-2,FOXP1,PAK5,TMBIM1,PELI1,PPARA,PRNP,HAX1,VDAC1,ENO1,HSPD1,TERT,PIH1D1,NFKB1,ARG2,NUP62,PSMC5,CCL2,HCLS1,NPPC,PPIF,PIAS1,VPS54,CCL19,MIR222,POU3F4,CD2AP,CD38,LACRT,TFRC,BIRC2,PTCRA,LAMP3,MAGEA4,PDCD1,GPAM,TAF9,TRIM32,SMAD3,MIR24-1,MIR101-1,SLC7A11,CCAR2,CREB3,NOG,RGL2,NME2,AKR1B1,TMBIM6,TXNDC12,TMIGD1,BFAR,CLU,BNIP3L,TIMP1,VEGFA,IVNS1ABP,MECP2,VSTM2L,PRELID1,MIR181C,FBXO7,NFE2L2,HIGD2A,HSPB6,RXFP2,DDAH2,NIBAN2,AREL1,NTRK2,NDUFAF4,YWHAZ,MIR30E,DNAJC5,NR2E1,PIK3R1,CDSN,ROCK1,PDCD4,NTF4,TCIM,ICAM1,PIK3CA,BIRC5,CD40LG,HNRNPK,LEP,ATF4,PIK3CG,KRIT1,PHB2,ANGPT1,SRC,RB1CC1,FAIM,XPNPEP1,TWIST2,COPS5,SHC1,KDM1A,MAD2L1,IRF7,CHST11,ADAMTS20,SLC35F6,IGBP1,SNAI2,BECN1,CBL,SOX9,CCR5,BAG3,CTNNA1,FZD3,CSNK2A1,CCL21,MIR20A,GHRL,RGN,GPX4,TLE1,FGF10,IL1A,KRAS,NOTCH2,DPEP1,GREM1,TNFSF18,HAND2,MTDH,CCR7,SEMA5A,DKK1,CEACAM5,GCLC,TNFAIP8,ING2,MEF2C,ST3GAL1,CD28,TAX1BP1,PTPRZ1,HSP90AB1,AGAP2,CDKN2D,PIM2,CAV1,SOCS3,PSEN1,FXN,IL4,BRCA1,HSPA5,HTRA2,ZFAND6,SOCS2,MIR142,NUPR1,PRDX3,CRYAB,HSPB1,DAPK1,HSPB2,PPIA,IGF1R,MIR126,CREB1,SFRP1,IER3,SNCB,MYC,DLX1,GBE1,GLO1,IL2RB,CCL5,MIR106B,DAD1,CFL1,RNF34,HEY2,MAP3K12,IL6ST,SMAD5,CSF2,CNTFR,LILRB1,PELI3,CDK1,SCG2,MIR132,BCL10,HNF1B,MIF,STRADB,SLC25A5,NPY5R,OGG1,ADNP,CITED1,CTTN,RB1,RAG1,ASIC2,CDKN1A,HSP90B1,CFDP1,PSMD10,MIEN1,UFM1,FOXC2,SLC25A27,ACVR1,AIPL1,MIR17,MIR214,RNF144B,PRKCA,NEFL,TRAF2,MIR145,CX3CR1,MSX1,SLC25A4,PTGFR,PPT1,IL10,RAF1,SLC39A10,CX3CL1,NAA15,TNF,DDRGK1,MIR361,ZNF304,HRAS,BCL6,CXCL12,PLAC8,STUB1,DFFA,MIR495,ORMDL3,MTRNR2L7,IL7,PYCR1,MIR195,RBCK1,FSTL1,EPO,RAD21,MNAT1,CLN8,NR4A2,LGALS3,FATE1,RETREG1,UFL1,FCMR,NAA35,PRKCQ,CDKN1B,BTG2,HELLS,NQO1,IL13,SOD2,ITGA6,MITF,FKBP8,MAEL,ST6GAL1,TP53,IDO1,DIPK2A,MDM2,API5,IFI6,EYA3,GHITM,NONO,ARF4,MIR590,SMG9,TMEM14A,KLF4,HSPA8,ADORA1,PTPN1,MGMT,PRDX2,PCGF2,ITGAV,ACKR3 |
| 2.082e-13 | -29.20 | HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3) | protein interactions | 220988 | 450 | 198 | 19454 | 5460 |
FERMT2,NDN,GAS2,PTEN,MIR16-1,CCNF,CTNNA1,PAIP2,STK24,MIR145,ATP5F1A,NONO,USP14,HMGB1,MIR7-3,FBXW7,CLK1,MIRLET7I,MTDH,MIR34C,RPA3,MIR205,SIRT7,HNRNPH3,MTRES1,LMNA,METTL14,GRM2,MIR1-2,SF3A1,CDK9,DCUN1D1,TOP1,PRNP,MIR25,MIR106B,MIR34A,FGR,ATP1B1,GRSF1,RPS13,VRK1,HSD17B10,PPP1R12A,RAB1A,FAF1,MIR20A,MIR17,MIR15A,MIR200C,MAP1LC3B,EEF1A1,GGCT,FBP1,MIRLET7D,CPSF1,MIR363,MYO6,BRCA1,LMNB1,MIR98,CUL2,CUL3,MIR106A,NMRAL1,CRY1,PSMA3,WDR77,DHX15,MIR141,RPLP2,PHB1,MIR7-2,MIR1-1,MRPS26,HNRNPD,HNRNPA1,PDIA3,CRIP1,RAD21,SSRP1,G3BP1,HNRNPA2B1,OTULIN,CYB5B,EZH2,NGB,CHMP4C,TXNRD1,SMURF1,SRPK2,PSPC1,UQCRC2,IGF2BP1,UBE2H,SPOP,ZFAND6,EIF4E,MIR107,HSPA5,MIR29A,PGK1,HNRNPH2,RNF113A,MIR10B,BAP1,MIR21,HEXIM1,MIR7-1,RPA2,MIR34B,TMPO,RBM42,MIR429,FZR1,RPS16,CAND1,MIRLET7G,SYNCRIP,SSBP1,CD274,UBE2N,CHCHD1,SNRNP70,CD81,COPS5,GAPDH,DPP4,MIRLET7C,MEPCE,MIR16-2,NEDD8,H3C1,HNRNPK,DHX9,MIR9-3,MIR200A,NUPR1,MATR3,ATP5F1B,SNRNP40,TAX1BP1,MIRLET7B,ICAM1,FBXW11,BTF3,SNRPB,MYC,HNRNPC,HNRNPAB,UFL1,PHB2,EEF1G,STAU1,HDAC5,HSPA8,DDX5,RAB5A,NGRN,SNRPA,RPS28,CNDP2,PIH1D1,CTBP1,PAK2,PABPC5,DUSP14,CHMP2A,HNRNPL,MIR9-1,TCP1,EED,MIR214,MIR221,MIR140,MIR31,AGR2,FKBP4,MIR29C,DDRGK1,MIR143,WWP2,HNRNPDL,HNRNPF,MIR155,EWSR1,MIR206,RTCB,MIR9-2,LSM14A,PABPC1,RHOBTB1,ISG15,MIR222,SOX2,EEF2,TOP3B,ARFGEF1 |
| 2.100e-13 | -29.19 | LMBR1L (limb development membrane protein 1 like) | protein interactions | 55716 | 944 | 366 | 19454 | 5460 |
EIF2S1,UQCRH,VAMP7,PTK7,LAPTM4A,MAGED2,DIPK2A,SPINT2,DRG1,HSPB1,FAM20B,UTP6,VDAC1,RINT1,RABGGTB,SEC11A,PDIA6,GLE1,CRELD1,ARFGEF1,TIMM21,ATP6AP2,ANAPC2,SPCS3,OSGEP,MLF2,RNF5,EMC1,SSR3,RER1,LCN1,STK26,PLAA,TMEM115,UBAC2,SIGMAR1,FAM8A1,FDFT1,SLC19A2,NDUFAF3,TMPO,ILVBL,GLT8D1,STT3A,TRAPPC3,TUBG1,CMSS1,KARS1,DNAJB2,GPRASP2,SRPRB,TOLLIP,KPNA2,TMEM33,FKRP,FKBP8,ATP2B4,STX18,SLC16A1,TRAFD1,TFRC,TMEM165,PSMC3,TSPAN3,NAA35,PREB,UBL4A,CDK4,MTCH2,UBIAD1,ZMYM3,KCTD9,SC5D,ADRM1,CSTF3,PSMC5,SGTA,ATP1A1,CHPF,NCAPG2,MARS1,CD46,GALNT1,EIF2B3,SAMM50,USE1,HECTD1,CFTR,OCRL,ATXN10,ERLIN1,NDUFS8,PHB1,XPO5,GJA1,RPLP1,EMC6,EMC8,MCM6,HS2ST1,RFC3,UBE3A,STIM1,RNF126,PLD3,FEN1,EMC10,YIPF3,GFPT1,NUP153,RPL7L1,UMPS,CHCHD3,GNB1,TNPO3,PELO,RMDN3,SERINC1,FZD6,SARM1,ATP1A3,MYO6,LMNB1,EXOC8,VEZT,FMC1,SAMHD1,NPTN,TMEM127,ATAD1,PSMC1,ZDHHC17,NT5C3A,UNC45A,ATP5MK,HADHA,ATP5PO,NDUFA5,FAM234A,MTX2,OTULINL,TIMM29,RAB6A,EIF2B2,MAPRE2,EIF2B5,SLC25A12,HACD3,SRPRA,SEC23A,ESYT1,DNAJC7,EMC4,LRRC40,APH1A,TOM1,ARF4,GALNT2,SEPTIN7,EMC2,TMX3,SRP72,CCDC47,TBK1,LBR,RAB14,MGAT1,VKORC1L1,TECR,SEC63,SCAMP2,GSK3A,GANAB,DCAF16,XPOT,EPHA2,NDUFB10,CREB3,KPNA6,TUFM,USP14,SMC4,TMEM209,NCDN,PNO1,SQSTM1,EGFL7,P3H1,TIMM23,TTI2,TM9SF1,IFRD1,PSMC4,CLSTN3,FUT8,HACD2,HSP90AB1,RPRD1A,FUBP3,STX5,CDC23,DDX1,XPO1,NDUFV2,YWHAH,DDRGK1,CTNNB1,QPCTL,PSMA1,PTRH2,NDUFA12,NCSTN,TMEM59,PSMB6,POLR2B,ALG5,NCKAP1,LMBR1L,VDAC2,GGT7,RETREG3,SERPINH1,PSMD1,BAG3,UFL1,NDUFS2,PHB2,CERS6,JAGN1,TAPBP,NUFIP2,TOMM22,CCDC167,GPC4,SEC62,TOM1L2,PLG,CAND1,VTI1B,TMED9,SLC38A2,LMAN1,XXYLT1,NUS1,DHRS7,NUP107,PDE12,RHBDD3,CSE1L,RDH11,GALNT12,YIF1A,SURF4,CAPN2,ATP5PB,CDIPT,NECTIN2,SEC61A1,PPP2R5E,PTPMT1,ATP1B3,ENDOD1,DTL,TRIM32,PSMB2,SLC25A1,CCNB1,ARL6IP6,GORASP2,CNNM4,PIP4P1,ITM2B,DERL1,SSR1,CHPF2,CYC1,LEMD3,PSMB4,ATP6V1A,VCPIP1,VPS4A,SEMA4C,GTF3C3,SACM1L,HECTD3,BAG2,RPN1,BZW2,STX12,NAA15,HSDL2,B3GNT2,DCAKD,PPP2R1A,RPL29,FAF2,ERLIN2,RANBP6,ABHD12,USP5,BAX,SCFD1,SRM,STX7,PXMP2,ATP2C1,DNAJC3,EXD2,PSMA3,VAPB,PSMB7,LARP4B,FKBP10,ARCN1,TOR1AIP2,PGRMC1,COG1,TOMM70,POR,MUL1,OSBPL8,HM13,DAG1,HUWE1,RNF115,ERLEC1,FARSA,FASTKD5,PTGES3,RIGI,RAB1A,FAF1,SFXN1,TCOF1,NDUFS3,ADAMTS1,VAC14,DHRS7B,NDUFA2,SELENOK,NRM,NRSN2,UQCRQ,CEP97,CTNNA1,SDF2L1,AP2A1,LRP6,HSPA14,HMOX2,SLC7A1,DAD1,TMUB1,HELLS,DVL2,PPM1G,RTN4,SPCS2,SLC12A2,STOM,RARS1,RABL3,PCK2,TIMMDC1,SEC22B,SLC35E1 |
| 2.198e-13 | -29.15 | SRP68 (signal recognition particle 68) | protein interactions | 6730 | 353 | 163 | 19454 | 5460 |
CCDC47,RPSA,AURKAIP1,RPL15,RBM34,DISC1,ILF2,SRP72,METTL18,NKRF,RPL3,RPL23A,HAPSTR1,ABCE1,DHX9,SRPRB,MEPCE,RPS13,SMN1,MDC1,RPL17,EIF3E,HDAC6,COPS5,RPL24,RPS2,RPL10A,RPL12,SRP14,SRPRA,ARL10,UBE2N,RPL32,TES,CAND1,RPL35A,RPS16,FZR1,CGAS,RPS27L,CDK9,RBM42,CDC5L,ZBTB2,SURF6,RBFOX2,RPS14,TPT1,CFTR,EIF3J,CDK7,RPA2,METTL14,RPL26L1,HEXIM1,RPLP0,RPA3,RPL27,BAP1,SIRT7,PNO1,MTDH,RNF113A,RPS15,RPL4,EIF4E,ZC3H15,BRIX1,RPL7A,RPS17,RUNX1,EIF3G,IGF2BP1,PDCD4,UBE2H,MAPRE1,CCNF,PELP1,PSPC1,RPS3,METAP2,FGFBP1,PRKRA,SRP54,EIF2S2,RPS20,RPS12,ZNF622,RPL13A,VIRMA,RPL22,TRMT1L,RAF1,SOX2,RPS7,RPN1,EXOSC3,CHMP4C,SEC61G,PDHA1,RPS11,RPS23,MOB3C,RPL18,RPL31,PABPC1,PPAN,RPS24,KRAS,RPS4X,RPL28,IFI16,RPL6,WWP2,XPO1,EIF3D,DDRGK1,MED4,RPL8,RPL9,SRSF1,RPLP1,RPLP2,EIF2S1,RPS10,SUMO2,RPL7,LYAR,RPL27A,NUFIP2,RFC4,RPS28,HSPA8,EP300,FXR2,STAU1,SSR3,G3BP2,MYC,CUL3,NOP16,RPL39,ZNF668,RFC5,RPS29,FTSJ3,BRCA1,H1-10,RPS26,H1-1,LMBR1L,FAU,EIF3K,DLST,UBE2S,RPL37A,SEC61B,TAX1BP1,RPL35,ESR2,PRRC2A,RPL10,RPL19 |
| 2.224e-13 | -29.13 | RPL9 (ribosomal protein L9) | protein interactions | 6133 | 364 | 167 | 19454 | 5460 |
RPL23,DRG1,AHSA1,AGR2,CTNNB1,MAP3K14,DDRGK1,RPL6,WWP2,RPL7,RPS10,RPLP1,RPLP2,EED,PHB1,RPL8,RPS23,RPL18,RPS11,CHMP4C,PNMA2,EZH2,RPS7,DNAJC25,RPL29,SUPT5H,B3GNT2,RPS4X,RPL28,RPS27A,ZBTB14,TRIM37,TNF,KRAS,RPS24,MRPS11,SREK1IP1,RUVBL2,RPL31,SLC25A5,POLR1B,ICAM1,RPS26,RPS5,COP1,FTSJ3,BRCA1,ATG3,RPS29,DRAP1,RPL39,MRPL16,BTF3,CUL3,CUL2,STAC3,MYC,RPL10,RPL19,RPL35,SNRNP40,SEC61B,RPS9,RPL37A,SMU1,CMTR1,ARF1,PIH1D1,EIF4B,EMC9,PPT1,PPARG,RPL27A,G3BP2,COIL,STAU1,UFL1,TIFA,CCDC184,HDAC5,RPS28,RPL10A,RPS2,RPL24,SNRNP70,HDAC6,COPS5,EMC4,ENY2,MOV10,KXD1,CDC5L,RBM42,TMPO,PRNP,RPS27L,CAND1,DNAJC1,RPL35A,RPS16,FZR1,DCUN1D1,RCHY1,RPL32,ARL10,RPL12,SRP72,ILF2,DNAJC2,RBM34,TNFAIP8L1,RPL15,EEF1A1,RPSA,UBL4A,RPL17,MEPCE,ARF4,MRPL22,RPS13,VRK1,PPP1R27,DHX9,RPL3,RPL23A,UBE2H,RRP7A,EXOSC1,TUFM,PPP1CC,RPS17,RPL7A,DHPS,CIAO1,SLC25A1,VIRMA,RPL22,RPL13A,RPL10L,NDN,RPS20,RPS12,PRKRA,CTTN,METAP2,CCNF,PSPC1,RPS3,RPLP0,RPL26L1,HEXIM1,GRM2,METTL14,RPA2,CFTR,TPT1,RPS14,FBXW7,RPL4,RPS15,NPM3,RNF113A,SIRT7,NLE1,RPA3,BAP1,RPL27 |
| 2.286e-13 | -29.11 | RIN3 (Ras and Rab interactor 3) | protein interactions | 79890 | 456 | 200 | 19454 | 5460 |
HECTD1,ANGPTL2,H2BC11,CD2AP,GRPEL1,RGS2,HSPA5,SNX33,PRDX6,TNFAIP1,RPL27,PML,ATP1A1,DNAJC10,TYW3,RAB2A,RPL7A,SUB1,BUB3,EIF4H,CSNK2B,ZNF655,RPS3,GRAP2,CAPZA2,H2AX,IPO8,RPSA,CDK4,SRPRB,HNRNPK,DHX9,RPS2,LANCL2,SHC1,RPL24,CSNK2A1,TPM3,GAPDH,RPS16,RPS27L,RAP1B,EEF1B2,SDHB,RPL32,ALYREF,RPL27A,MT2A,PACSIN3,EEF1G,PHB2,HSPA8,SF3B1,RAB5A,RPS28,DNAJB6,CKB,CCT2,S100A11,HMGCS1,TM4SF19,MYC,LDHB,RPL10,NCKAP1,ATP5F1B,PRMT5,CRKL,AAMP,RPL18,PLS3,PIR,TUBB4B,H1-3,EEF2,RPS7,TOP3B,RPS4X,DCTPP1,HNRNPF,VDAC1,RUVBL1,RUVBL2,PDIA6,RTCB,FBXO3,CCT8,DDX1,YWHAB,YWHAH,DDRGK1,RPL6,RAB5C,HSP90AB1,CCT7,FAM98A,HNRNPL,TCP1,DYNC1I2,RAB31,RPLP0,RARS1,P3H1,CCNA2,PSMC4,RPS14,RPL4,SMC4,IRAK1BP1,IVNS1ABP,ATP5F1A,GMPS,CSK,RPL22,LDHA,TXN,RPL13A,RTRAF,RPS12,STUB1,TUBA1B,ILF2,EEF1A1,YTHDF2,RPS13,PTGES3,MSH6,RIGI,RAB1A,TCOF1,GLUL,DNAJC7,SUV39H1,ATP5PD,TOMM70,RPL12,AIFM1,HACD3,SLC25A3,VAPB,WDR77,PGRMC1,ASB8,ASB3,SKP1,CYFIP2,RABAC1,HADHA,HSP90AA1,RPS5,LMNB1,YWHAZ,MCM3,CUL2,RPL19,MAD2L2,PRDX2,DYNLL1,RPL35,TUBB,ACTB,RPS9,CYB5R3,RAN,RPS11,STK16,EZH2,CYP2C8,RPN1,NME1,PPP2R1A,ACTN4,RPL29,RPS27A,COPS4,AHCYL1,LASP1,TRIM26,KCTD17,ATP5F1D,HSD17B8,VPS26B,SRSF7,HSPD1,SLC25A5,HNRNPA2B1,CDKN2C,HNRNPD,RPL23,PRDX1,PSMD3,POLR3F,RPL7,SNX18,PBDC1,BRD9,RPLP1,RPLP2,RPL9,PHB1 |
| 2.295e-13 | -29.10 | SOAT1 (sterol O-acyltransferase 1) | protein interactions | 6646 | 283 | 137 | 19454 | 5460 |
ETFA,VDAC1,KRAS,RPL28,TMT1A,GPAA1,SCYL2,SLC25A5,RTCB,MKLN1,NME1,STIM1,RPN1,CRELD1,RND3,RANBP1,MARCKSL1,EEF2,ERLIN2,DNAJC25,YIPF3,RHOH,PPIA,ERLIN1,RAB35,BPNT2,PPM1B,RHOG,YWHAB,RB1CC1,RAB5C,STOML2,LAMP2,PDIA3,EYA3,STAU1,EEF1G,BOLA2B,EMC1,HSCB,RNF5,RNF11,TMEM106B,VAPB,NDUFA5,SLC25A3,APOC2,TOMM22,MTMR6,DIO3,MRPL12,RND2,OTULINL,PRDX3,SEC62,POPDC2,MTM1,ACAP2,ARF1,VDAC2,SEC61B,LMNB1,CHTOP,H1-10,YWHAZ,CKB,FAS,VMP1,FIS1,PYCR1,RAB11A,LDHB,MYC,HSPE1,FKBP8,PSEN1,SFXN1,SLC25A10,LRRN4CL,SLC16A1,NDUFS3,SEMA7A,ILF2,TP53,CCDC47,UBIAD1,DNAJC1,LMAN1,DKC1,TMPO,COX4I1,EHBP1,ALYREF,PTPN1,AIFM1,RAC2,HSD17B11,FAM187B,ESYT1,UPK1A,SLC25A46,LAMP3,PDHB,TSPAN5,GID8,BANF1,RPA3,RPL27,DERL1,RAB9A,PRDX6,SYVN1,IDH2,SSR1,STOM,HSP90B1,JUP,ACACA,RARS1,EEF1E1,ST7,CDC42,UQCRC1,LYPD6,SLC25A4,LDHA,TXN,SEC63,DUSP3,TECR,STUM,UQCRC2,GANAB,SAYSD1,OAT,RAB2A,CSK |
| 2.317e-13 | -29.09 | SFXN3 (sideroflexin 3) | protein interactions | 81855 | 153 | 86 | 19454 | 5460 |
PDCD1,HSPB1,LAMP2,FAM174A,HNRNPL,SPTAN1,RHOH,RAMP3,TLCD4,VAMP2,AQP3,PDHA1,TMEM14B,RAF1,B3GNT2,VDAC1,LEPROTL1,OSTM1,NDUFA4,RHOB,FCER1G,THTPA,ILK,MYC,SCN3B,GPBAR1,REEP4,APLNR,PARL,MAD2L2,ESR2,VDAC2,DLST,RETREG3,ZMYM2,FAM3C,TOMM22,TOR1AIP2,TIMM17A,EMC1,UCHL3,NPTN,SLC15A1,STAU1,HSPA8,ESYT1,MOV10,LAMP3,HSD17B11,RAC2,NDUFS3,MGARP,CD80,TNFSF8,HUWE1,EDEM2,PDE2A,RUSF1,SFXN1,LRRN4CL,SYP,CREB3,TUFM,RHOJ,UQCRQ,VIRMA,DYRK1A,CCNF,TMEM108,ACAT1,SLC1A1,RPA2,STOM,GP9,MPV17,CDC42,PLP2,KLRD1,CFTR,CDK7,CLEC12B,TOMM20,RPA3,TMX2,RHOU,PML |
| 2.344e-13 | -29.08 | TAF15 (TATA-box binding protein associated factor 15) | protein interactions | 8148 | 389 | 176 | 19454 | 5460 |
COPS5,RBM17,USP15,SNRNP70,ARL4D,PREP,SYNCRIP,CDC5L,MIR429,MIRLET7G,CAND1,TMED9,IK,NFE2L2,DDX42,DHX9,MIR9-3,MIR200A,MIR16-2,MEPCE,MIRLET7C,HNRNPK,NEDD8,H3C1,UBE2H,RC3H2,CALML5,MIR34B,MIR7-1,HEXIM1,MIR21,TFIP11,ZNF326,RPA2,RNF113A,MIR10B,DDX46,MIR29A,MIR107,HSPA5,MIR29C,YWHAG,WWP2,MIR143,HSPB1,MIR140,DDX1,MIR221,MIR31,MIR214,EED,SRSF1,TRIR,MIR9-1,SNRPA1,SNRPD3,HNRNPL,SOX2,MIR222,SUPT5H,TOP3B,RHOBTB1,MIR206,EWSR1,TOP2B,PABPC1,LSM14A,MIR9-2,HNRNPDL,CCAR1,RUVBL1,MIR155,ZNF609,SNRPB,HNRNPAB,SFN,HNRNPC,MYC,THOC6,MIRLET7B,SMU1,SNRNP40,MATR3,ACAA2,EP300,DDX5,DDIT3,HSPA8,SF3B1,SNRPA,SAP18,PHB2,TRA2B,MOV10,MIR34A,MIR25,MIR106B,CDK9,THOC1,TOP1,DCUN1D1,MIR15A,MIR200C,RNF181,POLR2G,ILF2,MIR17,MIR20A,GLUL,PPP1R12A,SOCS2,THRAP3,USP14,NONO,AR,RUNX1,CNTNAP1,MIR145,ENO1,CCNF,MIR16-1,MIR1-2,SF3A1,SAP30BP,MIR34C,MIRLET7I,SIRT7,MIR205,RPA3,MIR7-3,FBXW7,GTF2I,NF2,HNRNPA1,PRPF19,TAF7,MIR1-1,DDX23,MIR141,PHB1,MIR7-2,THOC2,DHX15,CCAR2,OCRL,RAF1,B3GNT2,SNRPE,POLR2C,EZH2,SRSF7,HNRNPA2B1,SLC25A5,SSRP1,MIR98,CUL3,CUL2,MIR363,DCAF4,BRCA1,LMNB1,SNRPD2,SNRPD1,RSRC1,CPSF1,TAF11,SNRPB2,MIRLET7D,PRDX2,PPP1CB,WDR77,MFAP1,NUP50,THOC3,MIR106A,AZGP1 |
| 2.422e-13 | -29.05 | biosynthetic process | biological process | GO:0009058 | 4231 | 1437 | 18204 | 5365 |
ATG16L1,CMTR1,TRMT1L,SMAD3,GPAA1,SNRPN,TAF9,HNRNPD,EIF4A3,SELENOK,NXT2,ZDHHC4,PPAT,WDR83,ATF3,AKR1B1,SNRNP27,ELP3,DNAJC4,NDUFA5,GFUS,TYW3,CLPX,PRSS37,PRSS12,FOS,RPAP2,CYP2C9,HNRNPF,HINT2,MRPL18,B3GNT2,ARG2,THTPA,KCNJ8,NFKB1,LIPT2,P3H1,PLP1,SUPT3H,MGAT4A,NUDT12,THBD,TTC1,GSTM4,CHKB,SELENOI,TXNL4A,ACAT1,TMEM59,TENT2,ZRANB2,PGRMC1,GPR37,DTL,RPL8,FAU,RBM27,PGM1,MRPL53,MEF2A,PRKRA,OAZ3,DHX38,PTGES3,GXYLT2,EXT1,MTMR2,NRDE2,SRGN,PPIL3,SRC,ANGPT1,PPID,ISCA2,METTL6,PSEN2,CHDH,CHPF2,ATP5MC3,MGAT4B,ATF4,NOVA1,POLR2F,HNRNPK,SF3B6,TICAM1,UBL5,MECP2,B4GALT4,ADGRG1,BMPR2,MRPL50,CELF6,EXOSC3,KRR1,SLC30A5,IRF1,DNAJC5,PQBP1,TMEM208,MAN1A2,PIGK,C1GALT1C1,UTP15,IFI16,RPS24,PGK1,TLCD3B,CCT5,TFIP11,ASNSD1,HS3ST3A1,METTL14,NBN,EP300,GEMIN8,RFC3,UQCC3,CRYL1,WDR77,RPN1,PIK3R3,CSTF3,NPC1L1,HSD17B10,CRTAP,RPF1,SLC1A2,NPR2,TMEM106A,DPH3,MRPS35,AKAP17A,GON7,PRMT5,MRPS34,GRB10,ISG20,CHPF,TSPAN15,KPNA6,AKR1A1,SPTSSA,EIF3G,ADCY2,BAD,B4GALT7,CDK12,GAMT,RIC3,TRIM24,GYS1,ATG4C,STOML2,ASMT,POLR3B,DUOXA2,SNRPB2,RNF14,MAT2B,PNP,MRPS7,HSPD1,THUMPD1,IMPA2,MRPL11,LUC7L3,UPRT,SLC1A3,OSGEPL1,SNAPC3,LYAR,ELK1,EIF4E3,POLR3F,SNAPIN,RPL26L1,MPHOSPH10,RPLP0,H3C1,RMND1,ESS2,RWDD1,TIA1,ENPEP,MRPL22,INHA,METTL2A,RBFOX3,GALNT2,PLAAT3,ADIPOQ,ETF1,EEF2,RPS3,RPS29,HMBS,MME,PIR,S100A10,BRIX1,PRPF4,DPAGT1,BATF,RPF2,SPHK2,PPAN,SPCS1,QRSL1,ANKH,OGG1,MTRES1,DIS3L,CFTR,KTI12,SCN2B,RPS16,LDB1,BOLA2B,RPS28,ACOT8,PFDN1,TAF7,IDO1,SPPL3,VPS72,ZMAT5,PEDS1,FGFR1,MTHFD2L,ATXN1L,NDUFAB1,HELT,ACSS2,PIWIL4,GGTA1,POLR1B,UGDH,NONO,TSEN54,MRPS18A,FKBP10,SEC11A,LSM6,POLR2L,CLN8,GNPDA2,MYRF,EDEM3,RPS5,SLC25A11,PYCR1,AASDHPPT,ATP5F1E,AK3,MRPL47,TSPO,GNPDA1,KDSR,GLE1,LIPA,ACOX1,NSDHL,CYP7A1,CCNA2,RPL23,TAMM41,PLSCR3,SRPK2,POLB,SNRPD3,SLC6A3,DTWD1,TGFB2,METAP1,PCNA,SNAPC1,ATP5F1B,TCEANC2,NDUFA1,GAL3ST1,NFKBIB,PXYLP1,EIF3J,FMO1,QNG1,NPM3,TTC4,RTCB,PDHB,FARSA,PIWIL2,RP9,PFDN2,ERG28,MACROH2A1,AHSA1,WDR3,SNRPA1,SNRPE,GPX4,PRCP,TECR,CWF19L1,MTARC2,HYCC2,ETNK2,CDK7,NDUFA2,MRPL36,CISD1,DNAJC19,DNAJC30,SPON1,PMPCA,THOC2,MRPL16,HNRNPA1,WWP2,SELENOF,CREB1,SLU7,HSPB2,G6PC3,SCNM1,TDRD7,PTGES,OST4,INPP5K,EIF2S2,POLR3GL,NDUFA12,SOCS4,HSP90AA1,USP15,WDR45,DAD1,PFDN6,ATP6V1A,FCF1,SMG5,MRPS33,FKBP1B,CD28,CBFB,HSP90AB1,SMPD2,ZCRB1,ZMPSTE24,TAF2,SNRPA,WBP11,YBEY,POLR2I,PLPP6,ARB2A,RPS27L,EGR2,VSIR,APEH,CERS2,RBM17,GPAM,TRMT112,MED9,MED23,FA2H,CNOT6L,SYK,MAK16,HNRNPL,PCYT1B,ZDHHC17,TESC,EAF2,PPIC,APOBEC3C,ZC3H11A,SELENOT,RPL10A,NPPC,GLRX5,GCFC2,DNAJC1,RBM42,KIN,EIF5B,APOBEC3A,C1D,MRPS25,G6PD,PRPF31,TBCEL,DPP4,VPS54,TRMT10B,RPL7L1,CYP21A2,NMRK1,ELOVL3,F7,PIK3CA,TAF10,ATP5PB,CHST13,APEX1,THOC1,GFM2,SUPT4H1,CYP39A1,RPS10,NDUFAF6,CHTOP,UTP25,RPL35A,BACE1,RBM41,HSD17B8,CD40LG,UNC45A,RPS11,EIF3E,PPM1B,RRM1,SAMHD1,MGST3,GTF3C4,ST3GAL5,PIK3R2,AGK,CTNNBL1,DEK,HS2ST1,ELOVL4,CAPN2,NDUFB8,STT3A,PTDSS1,CDC40,CYB5R3,DIO3,SIRT7,VDR,BAK1,B4GAT1,PRPS1,CEBPE,BMP1,RPS4X,HACD4,FUBP3,PDRG1,CCT7,RPL26,FKRP,LBR,PIP5K1A,CKB,TAF11,RPL4,ACP5,B4GALT1,PCSK9,B3GALT2,ATP5MC1,SRFBP1,GLCE,DCK,PARL,DIO2,SMU1,XBP1,PNPO,RPL13A,RPL27,PFDN4,TERC,DOLK,PAIP2,HIRA,IL2,CYTL1,AR,MRPL52,SOD1,SNAPC5,POLD4,IMMP2L,POP5,THOC6,ABHD4,MMP14,EIF4E,NDST1,UTP6,CDIPT,DDX39B,PADI2,AGPAT5,RCL1,FOXP3,RPL12,GNPNAT1,CLIP3,TENT4A,DUS4L,GFPT1,URM1,PAX6,RIGI,WNT10B,RPL7A,PNPLA8,NUS1,SLC35C1,TUFM,PRKAG1,ATG7,HDAC3,MTAP,HM13,DNAJB6,MDH1,AQP11,B3GALNT1,RAMAC,CYP17A1,PPT1,TEX12,PHB1,DNAJC10,STUB1,RSL24D1,PLAC8,CERK,RPL28,PCLAF,CCT8,GTF2A2,SUPT5H,MED4,LSM3,MPST,CASP4,RPL6,TAFAZZIN,CD2BP2,GGT7,FDFT1,RP2,PDHA1,H2AB1,NLRP3,BOLA3,CASC3,FUT8,NHEJ1,ABCF1,CHST7,HENMT1,UBIAD1,FADS2,TRMT13,SPCS3,TP53,NCBP2,SLC25A39,DDX5,RPL35,RPL9,ZNHIT3,ZNF473,BAG2,INTS10,SCD5,HSPA8,PPIB,ST3GAL4,RBMX2,SORD,USP39,CYB5B,MRPS11,RARS1,CDC123,LGALS3,METAP2,WDR6,CYP27B1,PIWIL1,ZNF326,FAR2,HEXB,DROSHA,TRA2A,B4GALT3,DDX46,NAA35,FYTTD1,SLC25A12,RBM15B,TRMT61A,RBM3,GFM1,CHST9,ST6GALNAC3,PAOX,AANAT,SUGP1,SMNDC1,LTO1,LSM2,RPRD1B,DBR1,FKBP2,CHRAC1,RPP25L,SF3A1,THOC3,MAT2A,STAT6,RNF8,PRDM4,HAND2,DDX4,ADRB2,SRSF7,ZNHIT6,XXYLT1,EIF4EBP2,FKBP1A,CDC5L,PELO,PRPF19,DNPH1,DHX15,HSPA14,DRG1,CPSF4,AZIN1,DHRS7B,HNRNPA0,CPEB1,CSNK2A1,ERO1A,PPIG,BAG3,SART3,SOX9,IMP4,CWC15,QTRT2,MTRF1,CYP1A1,LSM8,RBM23,MVD,DNAJC25,SREK1IP1,HACD2,TLR3,DDX42,RPS14,MTMR6,ALDH1L1,SOCS2,AGO1,CRYAB,SECISBP2L,NDUFS8,NXT1,MIF,REN,PCSK2,EIF5A2,UST,MOXD1,TRMO,GPBP1L1,F9,RPL17,SWAP70,CMA1,YAE1,RUVBL2,THAP1,PAAF1,CDC37L1,GTF2H4,NDUFC2,FXN,ATP5PO,FAM98A,RPL37A,DGCR8,ATG4A,PCBD1,EIF1AX,CRTC2,POLD2,ELOC,CLU,CISH,RPL19,RPL3,MED30,SDS,HSD17B6,RPS7,PKNOX1,GRPEL1,TFCP2,BMPR1B,RPL32,UGP2,SLC11A2,SNRPD2,CBR4,EIF2S1,RPL24,FUT9,NDUFB5,GTF2E2,TERT,HS3ST1,MRPL33,PABPC1,ALOX5AP,MRPL20,CD2AP,FMO3,TSR3,MRPL24,ZDHHC16,FAM20B,DNAJC7,CSGALNACT2,NAA11,FKTN,DNLZ,NDP,GRM2,UTP23,UMPS,SERINC3,GALNT1,MED17,ELOF1,CPSF1,PDSS2,CSTF2T,NME1,SDR42E1,SERPINH1,PIWIL3,SMARCA5,EIF1B,TCOF1,MRPL51,SNRPB,LEP,SQSTM1,POLR2G,PTS,DNAJB4,GCNT3,GOLGA7,SACM1L,SMARCB1,NOB1,IVNS1ABP,HACD1,SLC38A1,DRAP1,PDIA6,SRSF4,GTF2IRD1,ALYREF,DTWD2,CCDC3,SNAPC2,MGAT1,EIF3K,EIF1AD,EIF2B5,PGS1,RPP25,CERS6,DR1,RPSA,MAGOH,PRKD3,NAA16,EIF3D,KARS1,GK5,COQ10B,POP7,SLC1A1,CYP2R1,CTNNB1,SHLD1,GPT,TSNAX,CYFIP2,NOP53,PYCR2,LSM4,PDIA2,RPS27A,GMPPA,SMAD4,MED31,DDX39A,PTEN,JAK2,GALNT17,TSR2,INTS6L,POLR1D,CRY1,UGCG,ABCE1,TUBA1A,ACACA,RIOK2,POLL,EIF2AK2,MRPS18B,ATP5IF1,RRN3,CYP2C8,THRAP3,RPS17,RNASEL,NANP,NDUFB6,ERP29,GTF2F1,VIRMA,HAS3,ENO1,AURKAIP1,TRPC1,GAL3ST4,EEF1A1,ST13,PPARA,UCK2,RPL39,PC,HSPA13,RPS23,KHDC4,MED29,ADCY3,DCAKD,ELOVL7,BAP1,SRSF10,HYPK,LIG3,IREB2,NDUFS3,RPLP1,NOS1AP,PCK2,NGDN,SYNCRIP,PRPSAP1,GUK1,CREBL2,HACD3,PHKG1,WDR82,ELP6,EEF1G,RPS2,ECD,NAA15,ZC3H15,POLDIP3,SRSF2,SRSF8,DBH,MSX1,PPP1R1B,ZDHHC8,DFFA,KLK6,H2BC1,HNRNPH3,GTPBP1,PYCARD,CD226,CARS1,INPPL1,EEF1B2,TSEN34,FRA10AC1,HSP90B1,ELOVL6,NFE2L1,TRA2B,GUCY1B1,TFB1M,LMAN1,MTHFS,WDR83OS,EIF4E2,AZIN2,PPIH,POMT2,PIP4K2C,PLSCR1,HSD17B1,HSD17B11,CHST10,ABCC5,ERCC3,FKBP8,NOP9,COX10,PGAP4,SRSF1,CMTR2,COMT,PSENEN,TBCE,RRP7A,POLE3,ENO2,DNAJC2,DDIT3,MNAT1,NR4A2,EPO,PTGDS,IKBKB,CHCHD4,EGR1,MKKS,RPS20,EIF4H,NCSTN,SPCS2,SDHC,SLA2,HDHD5,GOLGA7B,FAXDC2,ST8SIA4,POLE4,PPARG,B4GALT6,KRAS,DPY30,SAT2,PPP1R3C,GTF2H5,MRPL40,TWNK,NUDT2,RPP21,DRG2,IL2RG,GCLC,EIF2D,PGAM1,GSTM2,MPDU1,CREBBP,PROX1,RPL22,ZDHHC24,SMAD1,CCT2,COIL,ILVBL,FOSL2,COPS5,METTL25B,HNRNPC,MRPL9,MTF1,ATP5PF,AIP,HSPE1,MRPS28,TPH2,FITM2,MRPS26,TYW5,RPL23A,ACTMAP,MARS1,SLC25A1,HSPB1,ISYNA1,OAT,SRM,DDT,SNIP1,POLR2D,ATP6AP2,NFIL3,MED21,NAA50,PWP2,COQ8B,CAV1,SOCS3,PRDX4,RBFOX2,NDST3,MTG1,NAA60,CDKN2D,ODC1,NME4,ST3GAL1,POLR3H,RPP14,RBM22,IRF9,MPHOSPH6,CYP2D6,SMAD2,TRAM2,BUD31,BRCA1,ALKBH5,SNRPG,APOBEC3F,MRPS23,SNRNP70,SLC19A2,DTYMK,RNF113A,MRPS21,PSEN1,MTM1,MCAT,LHB,TCEA1,UCKL1,XPO1,GLUL,MRPS18C,PRKAB1,NPC2,MRM2,STAR,CH25H,GK2,MED10,MSMO1,SCG5,ARFGEF1,NOC4L,NME2,POLDIP2,FOXA3,MRPL17,SGF29,DPM2,INTS12,NOL7,CCAR2,MED22,MGAT5B,DHRS11,MRTO4,POLR2B,UCK1,HPGDS,WBP2,ATP5F1D,EXTL2,PIH1D1,PIGA,RDH10,HSD17B3,MRPL12,SGMS2,MRPS9,CCNH,MRPL13,GTDC1,RPS13,FKBP4,CYP1B1,ST8SIA5,YIPF5,AKAP8L,MECR,TRMT6,PPIF,WDR12,ADK,NDUFS2,GMPS,APMAP,RBMS2,FIG4,NUP107,SERINC1,DECR2,ADRM1,GNPAT,MAGOHB,WDR55,GTF2H2,CHST1,PBLD,NDUFB10,WRAP53,TOR2A,ABCG2,COX11,TRMT11,PIK3CG,HNRNPA2B1,VAC14,INSIG2,HSPB6,RPS12,ABHD2,GTF2E1,NDUFB4,MRPL41,RCE1,BCL9,GTPBP2,FABP5,RPL31,HMGCS1,CMPK1,PIK3R1,CCDC47,CUL3,NDUFS6,CPSF2,SLC52A3,TCP1,AK5,NIBAN2,PIGY,MRPL49,TRUB1,DKC1,APH1A,IGF1,SGMS1,MRPL23,WTAP,ENY2,CHCHD1,GRSF1,SKIC8,CALR,NUDCD3,GSTP1,INPP5E,ATP5PD,ELAVL4,KBTBD2,CLP1,AKT1,IL1B,MTERF2,METTL15,UBA52,EXOSC8,DNAJC24,EIF4B,SLAMF9,PPP5C,NR1H2,PLA2G5,FTSJ3,SLC25A10,DOHH,ACER3,RPRD1A,TSPAN5,CPE,EIF4A2,COQ8A,MSH6,DNTT,FBP2,ACSL4,NKX3-2,CYP27A1,CHAC2,POLR2C,DDX1,ZDHHC14,HEXA,TRAF3IP2,GP9,AGPAT1,IL6,PAIP1,LSM5,ACAA2,NOP58,DEGS1,ADAT1,SEPHS2,RPLP2,GGPS1,AKT2,HS3ST5,COPS2,DLAT,SLC37A4,FUT1,ERRFI1,DHPS,SF3B4,SMN1,ADSS2,MAD2L2,GMDS,PAPOLA,EDNRA,RPL27A,ACP6,TAPBP,EXOSC1,PIGW,MED27,GTF2A1,NCAPG2,ORMDL1,MGST2,RPL10,DHX16,OCRL,SRD5A3,CDC73,DNAJB2,RBM34,LPCAT3,B3GALT4,DNAJC3,ST3GAL2,CYP11B2,GRPEL2,SHMT1,TNF,SF3B1,DIO1,PDIA3,PDE12,ORMDL3,SSU72,PFDN5,HFE,BCL6,BCKDK,MED11,ATP5MK,FBP1,FITM1,MRPL34,OAZ2,ABHD5,HINFP,NFYA,RBM5,CDK9,DCTD,PRPF18,CYP11B1,TYMS,RSRC1,RB1,PTPMT1,ELOVL1,CITED1,IK,CHST2,GALNT12,GTF3C3,CEBPG,CNTN1,SNRPD1,RBM38,SDHB,ALDH1A3,MFAP1,DDX23,PIGC,ACCS,CIAO1,MAEL,ST6GAL1,EPOP,NDUFV2,SOD2,LEPR,FTSJ1,ZC3H7A,OAZ1,CSGALNACT1,GEMIN7,CHORDC1,ITGAV,SAP18,TMEM38B,TRIP4,EMG1,LARGE1,SPTSSB,B3GALT1,KLF4,IP6K1,TOR1B,INPP4A,POLR1H,TMEM165,IMP3,RPS15,TLR4,HMCES,GAPT,CYB5R1,GPHN,RPS26,B2M,PRIM2,EIF2B2,GTF2I,TCEA2,ALG2,BPNT2,PPWD1,NQO1,SNRNP40,CDO1,GSTA1,SUV39H1,MRPL10,MLF1,RPL15,PAPSS2,GMPPB,SC5D,GTF2B,OSBP,ATP5MG,LTB,ZMAT2,TRMT5,EIF2B3,RPL29,HYCC1,LIAS,PGAP2,COL3A1,DHX9,SDF2L1,SEPHS1,AMACR,PLA2G15,CCR6,UAP1,GALNT4,ZNF345,NHP2,TSN,BUD23,GAD2,CCS,SLC19A3,CTU1,IL1R2,NSA2,EXOSC4,RPL7,SUB1,RGN,PDF,ALG11,MRPS17,GXYLT1,BECN1,TOPORS,POLA2,DICER1,CHST11,SF3B5,ZDHHC15,SPR,TUSC3,GBE1,MMUT,PELP1,IFT172,SAT1,RCHY1,RTRAF,ARMC7,PPIA,PGAP3,ATP5F1A,PMM2,GTF2F2,TSSC4,NDUFB7,BARX2,OSGEP,SRSF12,EEF1E1,THG1L,FASTKD5,ALG5,AK2,SNRNP48,FURIN,RPL18,RPS9,MRPS16,KLHL3,HTRA2,HSPA5,SOCS5,MYD88,TAF5L,LSM10,RPL10L,MRPL57,CYP4F22 |
| 2.423e-13 | -29.05 | RPL19 (ribosomal protein L19) | protein interactions | 6143 | 559 | 236 | 19454 | 5460 |
RPL37A,SEC61B,RPS9,ZNF22,PRRC2A,MRPL23,RPL35,RPL7L1,ZNF668,MRPL16,RPS29,CUL3,NOP16,CUL2,RPS5,RIT1,ZCRB1,NOA1,CMAS,NOP53,MRPL57,YTHDF1,EMC9,RPLP1,RPLP2,RPL8,FOLR1,RPL9,PHB1,SRSF10,NOP58,RPL7,KCTD10,MAP3K14,MRPS35,MRPS26,RSBN1L,RPL23,MRPL18,RPS24,MRPS11,SLC25A5,RPS27A,MRPS17,UFM1,GNL1,TRIM37,OTUD6B,MAK16,B3GNT2,RPS11,SART3,CHMP4C,GSK3A,PRKRA,RPS20,RPS12,OPTN,CCNF,EIF2AK2,EIF4A3,METAP2,VIRMA,RPL22,NDN,RPL13A,RPL26,TUFM,PPP1CC,KIN,MTDH,RPA3,SIRT7,AATF,UTP23,MRPL20,NPM3,MRPL17,RPL4,FBXW7,HMGB1,CDK7,RPS14,RPLP0,RPL26L1,ZNF574,METTL14,PRR3,RPL12,SRP14,SRPRA,RCHY1,KRR1,MRPL24,RPL35A,MRPL50,HDAC6,APOBEC3F,MPHOSPH10,RPL23A,NKRF,MRPS18C,RPS13,MRPL22,PTGES3,PAK1IP1,VRK1,NOC4L,MAP2K3,RPL15,FBP1,MRPL11,ILF2,MRPL49,MRPL51,SRP72,MRPL13,CMTR1,RPL10,BTF3,RPL39,COX11,MYC,RPS26,ELAVL4,ICAM1,NSA2,MRPS25,FTSJ3,H1-10,ATG3,SF3B1,HSPA8,MRPL34,DDX5,RPS28,MRPS7,UFL1,STAU1,MRPL12,MTF1,RPL27A,NUFIP2,PIH1D1,RBM5,SRSF1,EIF2S1,ISG20L2,RPS10,MRPL9,NGDN,DDRGK1,DDX50,WWP2,RPL6,RIOX2,MAGOH,RPL31,PABPC1,FKBP2,RPS4X,RPL28,KRAS,SOX2,EEF2,RPS7,TRMT1L,RPS23,RPL18,GLE1,SEC61A1,SRP54,PSPC1,RPS3,BCCIP,RSL24D1,RPL10L,RPS17,ZSCAN25,RPL7A,UBE2H,SPOP,RC3H2,RNF113A,RPL27,BAP1,PML,WDR55,RPS15,MRPL41,MRPL40,MRPL10,GABRA1,CFTR,HEXIM1,ZNF770,KLF4,RPA2,SSR1,WWP1,MRPS9,RPL32,DKC1,MALSU1,SURF6,RPS16,CAND1,FZR1,SPPL3,RPS27L,COPS5,E4F1,KARS1,ENY2,NOL12,RPS2,RPL10A,USP15,SNRNP70,RPL24,RPL3,ABCE1,DHX9,MRPL52,MEPCE,RPL17,H3C1,NEDD8,H2AX,STRBP,UBL4A,MRPL47,TP53,RPSA,RNF8,RBM34 |
| 2.435e-13 | -29.04 | HSP90AA1 (heat shock protein 90 alpha family class A member 1) | protein interactions | 3320 | 1150 | 433 | 19454 | 5460 |
DCK,RB1,DCUN1D1,TOMM70,CDK9,MDM2,KLHL32,TESK1,FAF1,RPL23A,IGF1R,KLHL15,HUWE1,TTC4,PTGES3,MAP2K3,PPARA,SPSB3,KLHL26,SERPINA1,CCNF,EIF2AK2,ENO1,ZBTB17,NDN,CEP97,VIRMA,GNAI2,STK38L,FBXO7,TRAF3IP2,RHOBTB3,CDC73,PIM2,HERC4,RPA3,MIS12,PRKCB,TTR,PIK3R2,FBXW7,CXXC1,UBA52,CDK7,GABARAPL2,METTL14,MAP3K12,MET,WTAP,PSMB5,G2E3,SRSF10,PRKCQ,DYRK1B,HMGA1,ISX,HNRNPA1,RB1CC1,HAX1,UCK1,NEK9,MAP3K11,SLC25A5,BCKDK,HECTD3,TESK2,BAG2,ACVR1B,CDK20,AHCYL1,RAD21,RAF1,CKS1B,RPL29,PPP2R1A,GABARAPL1,JUN,PPID,CHMP4C,SNRPE,CNOT6,MARCHF9,TAB1,AIPL1,TUBB,MAD2L2,JAK2,MAP3K21,IRF1,PSKH1,YWHAZ,BRCA1,PFDN2,HSP90AA1,NLRP3,ILK,TERT,PSMA3,UCHL3,ASB3,CDKN1A,DET1,LARP4B,VPS18,FKBP1A,SSBP1,RPL32,UBE2N,CDK6,PLG,FZR1,CAND1,MIF,LMAN1,ANKMY2,GAPDH,TPM3,SHC1,AREL1,MAP1B,METTL18,NEDD8,HNRNPK,TGFBR2,MEPCE,RPL17,KBTBD4,ATP5PB,FAM162A,TP53,RPSA,BIRC5,SBK2,UQCRC2,ALG2,RCBTB1,CSNK2B,MAP3K3,DAPK3,DAPK1,ACVR1C,ACP2,NDUFAF2,AKT1,TRIM32,PRKACB,ST13,ABCG2,UBE2H,DDX46,BAP1,TRIM10,IRF3,NBN,PGK1,STK38,METTL22,CLU,BCL6,AGO1,MAFG,FGFR1,WWP1,DYRK2,RAG1,SIN3A,TTC9C,SUMO2,HSP90AB1,PRKX,IFI16,RPL6,WWP2,XPO1,YWHAG,YWHAH,DDRGK1,CTNNB1,MGMT,FBXO3,CDK5,EPHA4,CCAR1,RPS4X,PAK6,TUBA1A,NUDCD3,EEF2,TUBB4B,MOB3C,VEGFA,IRF2,VDAC2,FBXL14,PRMT5,STAT2,ESR2,MYC,HNRNPAB,PSMD1,BTF3,BAG3,CCT2,PSMD14,FBXW11,RPS6KA4,MDH1,CDKL2,BMPR1A,TMEM106B,RAMAC,UFL1,GINS3,MAP2K1,PPT1,CKS2,CSNK1A1,PACRG,EEF1AKMT3,ARL10,PRNP,CAV1,CDC37L1,HDAC6,CRBN,DNAJC7,FBXO34,FGR,STYK1,SPSB1,RGS6,NTRK2,CAMK2G,TF,WASL,HSPE1,FBXO25,TBK1,EEF1A1,MAP1LC3B,ENC1,STARD13,STUB1,GUCY1B1,GSK3A,UBASH3B,RPS20,PTEN,CEBPE,LDHA,YES1,CSK,ATP5F1A,AR,TUFM,CHORDC1,TXNIP,LGALS8,STK11,EPHA2,FLCN,SYVN1,SQSTM1,CERS2,HMGB1,RPL4,FBXO9,DNAAF9,ATG16L1,CCND1,PTP4A2,JUP,CDK1,HSP90B1,TTI2,RPLP0,FOLR1,PHB1,PTGDS,HP1BP3,SPTAN1,RPL7,CCAR2,CACYBP,PRPF19,ZBED4,MARCHF5,MAP3K14,PSMD10,CDKN1B,AHSA1,AKT2,ATF3,KLHL25,JAK1,G3BP1,PCGF3,RBBP7,TRIM37,DMPK,PCGF6,SAP30,EZH2,FBXL3,CDK5R1,NLRP2,RBBP4,BTG3,DSN1,ALDH1L1,CUL2,CUL3,RNF40,TOMM40,MCM3,GALE,WDR20,SP1,KLHL1,NTRK3,HADHA,TTC1,RNF10,IL1B,FBXL4,FOXP2,SKP1,UNC45A,KCND3,PPARG,ITK,AIP,MCL1,CD4,RPS16,TMPO,EPHB6,CDC5L,EDEM1,CSNK2A1,COPS5,HP,KLHL22,TUBG1,BECN1,DDR1,RPL3,DYNC1I1,CAMKV,CCIN,RBCK1,PDRG1,PIWIL2,FKBP8,PREB,UBL4A,CDK4,H2AX,TFCP2,NFE2L2,TNNI3K,TAB2,RNF8,RPS3,FKBPL,TSSK1B,SGTA,MKKS,KCTD9,PRKCE,ADRM1,MYG1,NR1I2,SRC,TNFAIP3,AKT3,SPOP,TRIM23,RC3H2,ATP1A1,NR1I3,HSPA5,SPTBN1,GABRA1,CFTR,SMYD3,RPA2,UBE2M,PRKCA,GSTP1,HEXIM1,TRIM36,SERPINC1,MAGED2,EIF2S1,PGR,ADCK1,TCP1,MAPK4,POGK,DIRAS2,IKBKB,AGR2,FKBP4,YWHAB,HSPB1,KLHL23,RPAP3,RUVBL2,KRAS,MAX,SUPT5H,ISG15,TRAF2,SERPINA3,SOX2,MTA2,RHOBTB1,NFKBIB,APEX2,ANAPC2,ATP5F1B,PSMD4,PPP5C,BRMS1,MLF2,DNAJB6,HDAC5,HSPA8,YAF2,SSR3,PAFAH1B1,PIH1D1 |
| 2.564e-13 | -28.99 | vpr (Vpr) | protein interactions | 155807 | 1003 | 385 | 19454 | 5460 |
ADD1,ACSL4,ITGA6,MIF,FZR1,GAPDH,KPNA1,DHX9,MYD88,CCR5,RDH11,MEPCE,SCML1,HNRNPK,TP53,IMP3,ATP5PB,BIRC5,DDX42,PIK3CA,CBX3,PPP2R5E,CALML5,RBMX2,CDIPT,IFI6,CTSB,PRKACB,CCNB1,IFI35,AKT1,SMARCA5,CDKN2AIP,GEMIN8,IRF3,HDAC3,CXCL8,LEMD3,CYC1,CYGB,HSP90AB1,PEG10,CHI3L1,SUMO2,SNRPA1,HNRNPL,SMUG1,YWHAH,YWHAG,XPO1,IFI16,BAZ1B,LAMP2,CDC23,AK2,IFNB1,OAS1,EWSR1,PIK3CG,S100B,CXCL10,MX2,HNRNPF,EEF2,DHX38,ETFB,CSTPP1,ISG20,PDHA1,DLST,MIDEAS,VDAC2,CBX5,MATR3,TAGLN2,STAT1,SNRPB,ZMAT3,HNRNPC,CREBBP,CIRBP,DDX5,CD40,TMEM160,GPX5,TRA2B,TOMM22,TRMT112,ACAA2,MAP2K1,MYBL2,ACTA2,SMAD3,WDCP,CDK9,CXCL11,SUV39H1,IRF4,MOV10,ECD,KIAA1143,IFNA13,RPL23A,TCOF1,GARRE1,TLR4,SMN1,RIGI,MAP2K3,POLR2G,CTLA4,MSN,TRIM27,CCL1,TNFSF15,JUNB,VIRMA,UBB,MGST3,RACGAP1,IL2,MAPRE1,RTN4,MIS12,PPM1G,IRF7,FTH1,CDK7,UBA52,PIP5K1A,SF3A1,IFIT2,PPIA,CD1A,HNRNPA1,VPS26A,PPP2R5A,IFIH1,PDIA3,DICER1,HAX1,HNRNPD,VCPIP1,DCAF11,DROSHA,HNRNPA2B1,GADD45A,HSPD1,SLC25A5,COPS4,RAD21,ATP5F1D,TNF,JUN,PPP2R1A,RPL29,ACTN4,CPT1B,POLR2C,POLR2D,EXOSC3,PRKAG1,POLR2F,ZMAT2,CD86,S100A6,PRRC2A,CCL23,LGALS3,ACTB,ATF1,CAPG,BAX,BRCA1,RHOB,YWHAZ,TERT,BIRC2,CD1D,NOP53,PPP2R3A,PPP2R2C,CDKN1A,MFAP1,IER2,VPS18,CD4,MCL1,COMT,COX4I1,GTF2B,SURF6,DKC1,CD28,TSEN34,CCL5,COPS5,XAF1,DNAJB2,KARS1,IFNA2,TMEM11,TUBG1,MNAT1,IL12B,CAPZA1,IL12A,KPNA2,TMEM33,DUSP1,HADH,H2AX,WBP11,MTCH2,CCL20,UBL4A,TFRC,QSER1,ZBTB33,RPS3,CREB1,TRAF1,PPP1R10,RALA,MORF4L1,GSTK1,AKT3,POLD2,CCL8,HSPA5,EIF4E,CCNH,SPTBN1,ACACA,PRKCA,GSTP1,IDH2,RPA2,VPS4B,RSAD2,SRSF1,POLR2L,TRIR,DYNC1I2,PAIP1,MRPL9,HSPB1,YWHAB,IKBKB,TRIM11,TOP2B,CD83,POLDIP3,IFNG,NUP42,VDAC1,TRAF2,ISG15,TOP3B,MTA2,NUDT19,BST2,GTF2F2,SF3B4,NFKBIA,NFKBIB,PSMD4,ATP5F1B,MLF2,TIMP1,PAPOLA,DNAJB6,POLR1B,FTSJ3,RBM27,EP300,STK26,HSPA8,FOS,ARG2,APOBEC3A,IL4,AIFM1,SLC25A12,G6PD,CAV1,POLR2I,LRRC40,CXCL13,NFKB1,CALR,SSX2IP,MPHOSPH10,PSMD7,HSD17B10,RING1,ZC3H11A,MDC1,IL6,CCL2,THRAP3,PAK1IP1,CD80,TBK1,CCDC47,RAD23B,GEMIN7,PPP4C,ACAT1,IFNA10,SLC25A4,YES1,NONO,ATP5F1A,PYCR2,CTSD,TXNIP,MTDH,H2BC12,SQSTM1,NUCKS1,CCL3,ELP3,EID2,MX1,SNRPN,WDR83,SAP30BP,RPLP0,CDK1,LMNA,COPS2,IL10,TSG101,PHB1,PPP2CB,CETN2,NDUFS8,CCAR2,SPTAN1,IFI27,NOP58,IDO1,LAT2,TRA2A,STOML2,BCL2L1,TRAF6,RHOG,MT3,AKT2,PCGF6,ANP32B,MCM6,ETFA,RBBP7,TULP3,NUP153,FEN1,CTSA,EZH2,SLC30A7,APOBEC3G,GNB1,MAD2L1,DYNLL1,MCM3,CUL2,RIT1,SP1,FCER1G,LMNB1,FAS,HADHA,G3BP2,FTL,TNFSF10,ATAD1,NSFL1C,IL1A,IL1B,IDH3B,PRKAB1,MYL6,APOBEC3C |
| 2.566e-13 | -28.99 | ATG16L1 (autophagy related 16 like 1) | protein interactions | 55054 | 1138 | 429 | 19454 | 5460 |
SIPA1L1,EDF1,WDR83,CPSF4,ATG16L1,SAP30BP,OXSR1,HSP90B1,JUP,SQSTM1,NHP2,SMC4,NPM3,PPP1CC,TUFM,NONO,ATP5F1A,DEPDC1B,SEC13,CSK,EPHA2,CCDC22,STK24,ACAT1,TMEM74,SNX12,OPTN,RPL22,HOMER1,TECR,YES1,SNX3,ZNF622,LDHA,MAP1LC3B,DDX39A,TBK1,CCDC47,MSRB3,ILF2,HSD17B10,ZC3H11A,STX8,EIF3E,CTNND1,ARF4,MRPL22,HSPE1,BACH1,TF,CTNNBL1,MED21,CDCA3,SRP14,HACD3,SLC25A12,CAV1,DBT,EIF2B5,TOP1,EIF2B2,PPP1R18,PPP1CB,NRDE2,WDR77,H1-5,MYL6,RTF2,PCLAF,EVA1A,THOC3,G3BP2,TGFB1I1,COIL,STAP1,RBM15B,MCM3,RFC5,CFAP20,USP13,TNFAIP8,SP1,LMNB1,AP2M1,FAU,CD79B,GNB1,RBBP4,DYNLL1,MB21D2,WDR37,GTPBP1,AP2S1,SF3B5,UBE3A,PPAN,TRIP4,RFC3,EIF2D,TRIM37,TRIM26,RBBP7,LASP1,LAT2,EIF3D,TRA2A,RAB3D,TAF7,RPL23,RHOG,RPLP1,GJA1,PHB1,MYEF2,TRAF3IP3,DNM2,CACYBP,ZNF593,RPL7,KCTD10,OCRL,ACACA,TRIM36,HEXIM1,GIT2,VPS54,RPA2,LCP1,EXOSC4,TLR2,CWF19L1,ARHGEF6,POLD2,BANF1,MARS1,TOMM20,KDM1A,EXOC5,GJB2,CEP85,MED22,MAT2A,RPF2,C9orf72,CALU,GTF2H2,STX10,MOB4,PSMA6,RPS3,SRPK2,TFEB,CSTF3,ADRM1,H2AX,IPO8,PSMC3,TAB2,IK,NHERF1,DNAJC2,TFRC,RPL3,ABCE1,NOSIP,CAPZA1,SRPRB,CSNK2A1,EDEM1,TCEANC2,CDK12,LANCL2,HCLS1,TANK,TMEM184B,XRCC5,RER1,HNRNPA0,EIF1B,PCCB,RUSC2,DNAJB6,THOC6,RBM27,FTSJ3,CHTOP,LAMTOR1,GTF2F2,EFHD2,NFKBIB,MYRF,PSMD4,ATP5F1B,CSTF2T,CBLN4,TNPO2,PPIL3,MTA2,ZRANB2,SMNDC1,CAAP1,PDIA6,RUVBL2,TOP2B,CCT8,RINT1,PABPC1,HNRNPDL,VDAC1,ARHGAP15,KRAS,GJB1,STK4,NT5C2,PPIB,ANKRD50,DRG1,YWHAB,UQCRH,TCP1,ABHD5,ST7,MED30,TXNL4A,WTAP,UBAP1,RARS1,PICALM,ZCCHC17,AP1AR,RAB33B,INPPL1,PRIM2,DVL2,PDHB,DHPS,CCHCR1,MSN,ALB,RPS12,TRIM27,CTNNA1,ENO1,TUBA1B,METAP2,CEP97,UQCRQ,CCT5,IFT57,SFXN1,PPP1R12A,ADD2,VRK1,FARSA,TSSC4,FAM133B,KXD1,MOV10,OSBPL8,ECD,SMAD3,CWC15,MRPS23,CDK9,NCBP2,THOC1,DET1,ELFN2,ACTL6A,NDE1,SLC25A3,EMG1,PSMA3,TXNL1,PPP2R3A,CYFIP2,PYCR1,RAB11A,ACO2,NLRP3,SETD7,HSP90AA1,YWHAZ,FYTTD1,MED10,SEC61B,RSRC1,PRRC2A,USP5,REEP4,MED17,RANBP6,PRDX2,PPP2R1A,RPL29,ACTN4,STX12,POLR2C,ITGB5,RPN1,BCKDK,HNRNPA2B1,SCYL2,HSPD1,SEMA4C,ASF1A,HNRNPA1,NDC80,HMGA1,ATG9A,PDIA3,HNRNPD,RB1CC1,MED4,CDK5RAP3,BRD9,RPLP2,PPIA,AGK,SNX18,ELFN1,LEMD3,CYC1,RPL27,OIP5,RPL7A,CARS1,SLC25A1,SUGP1,SMARCA5,CDKN2AIP,ALKBH5,EXOSC1,ENDOD1,BICD2,CSNK2B,TRAF7,RBMX2,NECTIN2,SF3B6,CCSER2,TXNDC12,RPGRIP1L,ELMO1,RPSA,GNAI3,CAPZA2,DDX42,EXOC3,CBX3,SURF4,RP9,DHX9,MEPCE,TNKS2,NUP107,GAPDH,ELOC,MAP4,MED29,MED27,ALYREF,METAP1,MRPS9,SSBP1,STX6,VTI1B,ZC3H14,SYK,CAV2,TRMT112,CSNK1A1,EIF4B,NUFIP2,NLRP6,TAPBP,RPS28,SPECC1L,DDX39B,EEF1G,KRT222,PHB2,TBC1D1,CPSF2,BTF3,ATG101,HNRNPAB,PRMT6,PSMA4,LDHB,ATG3,CCT2,PRMT5,VDAC2,ESR2,POLR2B,CBX5,TAGLN2,MATR3,STAT1,EEF2,RPS7,TMEM59,HEXA,TAF10,CSTPP1,LIMD2,EWSR1,LSM14A,PRPS1,CCAR1,RUVBL1,PSMA1,EXOC1,DDRGK1,YWHAH,XPO1,YWHAG,AVL9,DDX1,SWAP70,RAB35,HSP90AB1,CCT7,RAB33A,SUMO2,MITF,NOB1,RAB1B |
| 2.577e-13 | -28.99 | organonitrogen compound biosynthetic process | biological process | GO:1901566 | 1313 | 505 | 18204 | 5365 |
GALNT17,B4GALT1,CHPF,CKB,RPL4,UGCG,DCK,ABCE1,ACACA,DIO2,B4GALT7,ATP5MC1,B3GALT2,AKR1A1,GLCE,SPTSSA,ACER3,EIF3G,ADCY2,EIF2AK2,MRPS18B,PNPO,RPL27,RPL13A,EIF4A2,DOLK,MRPL52,ATG4C,PAIP2,GAMT,CYTL1,ATP5IF1,PRKD3,RPN1,CHCHD1,EIF3D,KARS1,SKIC8,CERS6,RPSA,IGF1,SGMS1,MRPL23,UQCC3,B4GAT1,TMEM106A,PRPS1,ATP5PD,SLC1A1,SLC1A2,GSTP1,NPR2,MRPS35,PYCR2,IL1B,MRPS34,RPL26,EIF4B,FKRP,RPS4X,HACD4,UBA52,RPS27A,EIF4E3,DCAKD,RPL27A,ELOVL7,ADSS2,GFPT1,RPS23,ADCY3,RPLP0,NUS1,SLC35C1,IREB2,NDUFS3,RPLP1,TUFM,RMND1,RPL7A,RPL26L1,PIGW,PRPSAP1,MGST2,GUK1,RPL10,HACD3,MTAP,ORMDL1,ATG7,RWDD1,SRD5A3,B3GALNT1,MRPL22,INHA,LPCAT3,RPS2,EEF1G,B3GALT4,ST3GAL2,AQP11,RPS17,RNF14,ZDHHC14,ACSL4,STOML2,ASMT,CHAC2,PAIP1,DEGS1,SEPHS2,NANP,EIF4E,HEXA,NDUFB6,NDST1,DLAT,MRPS7,AURKAIP1,FUT1,DHPS,RPLP2,HS3ST5,HAS3,PNP,UPRT,SLC1A3,RPL39,UCK2,RPL12,GAL3ST4,CLIP3,MRPL11,EEF1A1,EIF5B,UCK1,MRPL18,RPL10A,BMPR1B,NPPC,RPL32,SLC11A2,MGAT5B,MRPL33,MGAT4A,MRPL20,RPL24,ATP5F1D,B3GNT2,FUT9,EIF2S1,ARG2,EXTL2,NDUFB5,THTPA,PIGA,HS3ST1,CHKB,CSGALNACT2,MRPS25,RPS13,ST8SIA5,FKTN,NUDT12,MRPL12,SGMS2,FMO3,MRPS9,MRPL13,MRPL24,ZDHHC16,FAM20B,ACAT1,UMPS,TMEM59,EIF1AX,CERS2,UCKL1,GPAA1,ATG4A,PCBD1,ATG16L1,APEH,SELENOK,FA2H,MRPS18C,GLUL,RPL19,RPL3,SDS,ARFGEF1,PCYT1B,ZDHHC4,PPAT,SELENOT,TYW3,NME2,MRPL17,ZDHHC17,DPM2,RPS7,NDUFA5,EIF3E,GOLGA7,MRPL41,GTPBP2,HACD1,FABP5,PPM1B,B4GALT4,PTS,RPS12,NDUFB4,GCNT3,RPS11,MRPL50,CMPK1,SLC38A1,RPL31,BMPR2,SLC30A5,NDUFS6,MAN1A2,PIGK,C1GALT1C1,ST3GAL5,AGK,EIF3K,NDUFB8,MGAT1,EIF1AD,HS3ST3A1,MRPL49,STT3A,EIF2B5,PTDSS1,HS2ST1,RPS24,TLCD3B,SLC52A3,ELOVL4,AK5,ASNSD1,PIGY,ADK,NDUFS2,CHST13,GMPS,SERINC3,FAU,GALNT1,NMRK1,ELOVL3,PGRMC1,GPR37,ATP5PB,RPL8,RPS10,GFM2,MRPL53,OAZ3,ANGPT1,EIF1B,CHST1,EXT1,GXYLT2,NME1,NDUFB10,MGAT4B,ABCG2,CHDH,COX11,CHPF2,RPL35A,MRPL51,ATP5MC3,PELO,DNPH1,GAD2,ILVBL,XXYLT1,EIF4EBP2,COPS5,DRG1,SLC19A3,MRPL9,TECR,PDF,ATP5PF,ALG11,MRPS17,AZIN1,DHRS7B,CPEB1,RPL7,MTRF1,NDUFA2,MRPL36,CHST11,GXYLT1,TGFB2,ATP5MG,ST6GALNAC3,OSBP,MRPL40,GFM1,SLC6A3,CHST9,SAT2,NUDT2,EIF2B3,LTO1,RPL29,DRG2,PGAP2,PAOX,AANAT,ATP5F1B,EIF2D,PXYLP1,EIF3J,SEPHS1,FMO1,QNG1,GCLC,NDUFA1,GAL3ST1,HAND2,RPL22,ZDHHC24,PDHB,FARSA,GALNT4,MPDU1,MRPS33,NDST3,AK2,RPL17,MTG1,RPL18,MOXD1,EEF1E1,ALG5,ATP6V1A,ST3GAL1,SMPD2,ODC1,RPS9,NME4,MRPS16,NDUFC2,RPL37A,CYP4F22,SLC19A2,DTYMK,RPS27L,MRPS21,PSEN1,FXN,ATP5PO,MRPS23,RPL10L,MRPL57,HACD2,MRPS26,MRPL16,MMUT,RPS14,MRPS28,ZDHHC15,TPH2,DNAJC30,SPR,TUSC3,MARS1,SLC25A1,PGAP3,SECISBP2L,TYW5,RCHY1,SAT1,RPL23A,OAT,OST4,SRM,PMM2,EIF5A2,NDUFS8,ATP5F1A,WDR45,DAD1,EIF2S2,NDUFA12,UST,NDUFB7,ELOVL6,SPHK2,DCTD,EEF1B2,QRSL1,GGT7,TYMS,ELOVL1,NFE2L1,RPL6,GUCY1B1,EIF4E2,RPS16,AZIN2,MTRES1,CHST2,GALNT12,PDHA1,MTHFS,CHST7,PLSCR1,RPS28,SDHB,POMT2,FUT8,ABCF1,PPT1,GALNT2,ZC3H15,SHMT1,ETF1,RPS3,EEF2,DBH,RSL24D1,CERK,RPL28,ORMDL3,RPS29,HMBS,ZDHHC8,DPAGT1,CARS1,ATP5MK,GTPBP1,OAZ2,MRPL34,NR4A2,CLN8,EPO,AASDHPPT,ATP5F1E,EIF2B2,AK3,MRPL47,RPS20,GPHN,EDEM3,RPS26,RPS5,PYCR1,EIF4H,NCSTN,B4GALT3,GSTA1,MRPL10,GOLGA7B,TSPO,ALG2,KDSR,CDO1,SDHC,RPL15,PAPSS2,B4GALT6,GMPPB,RPL23,LIPA,ST8SIA4,IDO1,ST6GAL1,PIGC,CHST10,ABCC5,ACCS,SLC25A39,NCBP2,PGAP4,RPL35,FTSJ1,OAZ1,CSGALNACT1,COX10,NDUFV2,ACSS2,LARGE1,GGTA1,RPL9,MTHFD2L,NDUFAB1,TRIP4,UGDH,TMEM165,MRPS18A,MRPS11,RPS15,RARS1,B3GALT1,SPTSSB,ST3GAL4 |
| 2.709e-13 | -28.94 | TMED10 (transmembrane p24 trafficking protein 10) | protein interactions | 10972 | 244 | 122 | 19454 | 5460 |
EZH2,VAMP2,PDHA1,NCSTN,FAF2,SOX2,MACO1,TMED7,SAR1B,HS2ST1,EMC8,KRAS,PGAP4,TRIM37,TMT1A,FGF3,RB1CC1,CDK5RAP3,ATG7,DDRGK1,QPCTL,RAB5C,EGLN3,RAB11B,CYB5A,DUSP6,ARCN1,FAM3C,KCTD12,VAPB,SEC22A,GPC4,SEC62,ASB8,PGRMC1,LYSET,PSENEN,EMC1,UFL1,TMED3,DUSP26,HSPA8,PMAIP1,ATP2C1,JAGN1,TIMP3,TMEM106B,SCFD1,ARHGAP19,SLC30A5,TMED5,TMED4,B4GAT1,ESR2,SEC61B,LMBR1L,ARF1,CYB5R3,PIGK,SURF4,HSPA13,UBIAD1,LBR,APOO,PREB,UBL4A,PSEN1,GALNT2,SRPRB,APH1A,DNAJC30,GNG5,HSD17B10,EMC2,TMX3,MAN1A2,YIF1A,RAB1A,TMED1,MOSPD1,OSBPL8,RAB3A,POR,NPSR1,TMPO,SELENOI,LMAN1,FZR1,SPPL3,TMED9,MIF,XXYLT1,HACD3,GLT8D1,CD274,EPHX1,CYC1,LEMD3,RPA2,SLC12A2,SSR1,CDC42,RABL3,TPT1,SEC22B,HSPA5,PRDX6,BAP1,RPA3,RAB29,CALU,CDKN2AIP,FBXO7,GORASP2,RAB2A,VAMP5,TECR,VIRMA,RAB14,COPE,CTSB,MSN |
| 2.756e-13 | -28.92 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 15813 | 4641 | 16828 | 4835 |
FBXO11,SPSB1,RBBP9,WNT10B,DGCR6L,VIP,ETFB,LRRC8D,NTNG2,C1D,TFDP2,ZNF22,ACTR3B,MIF,ZNF189,EEF1B2,RBM15B,HRH2,AP2A1,APTX,RGMB,ZNF688,SPINT2,TMEM45B,BCL2A1,CD83,DNAJC7,KCTD12,UQCRQ,RPL12,GFOD2,ADAMTS20,SOD3,DUSP22,MTMR2,PLCL1,ICAM1,YWHAH,FAM187B,MRPL49,GABRB3,PABPC1L,LSM2,CCT8,TMBIM6,OR1S1,SH2D5,HMGA1,UTP6,MND1,GGPS1,TSPAN11,IPCEF1,AUH,ZNF267,IDE,TFRC,TTC8,HSD17B11,PPME1,ZNF177,ZNF652,C1QTNF1,LGALS3,NMBR,LUC7L3,HHIP,MAP4,SMYD3,DDIT4,RAB3A,CTNND1,KPNA2,FAM91A1,LCN12,OR10Q1,YIF1A,CA8,LRRC20,EGR2,HAX1,OR1F1,RPS3,TMEM60,CHN2,CALU,AIF1,HBEGF,FOXJ3,ORMDL3,USP30,UFM1,RAD23B,CLEC7A,APPBP2,GPR146,KCTD11,OPTN,ARPC2,GINS3,MYL12B,ENHO,IL7,ATP6V1E2,ZHX3,PID1,NECAP2,SRSF4,EXOSC3,SH3BGRL,TMEM42,SNX33,NDP,SDCBP,MED23,USP13,FGF3,DRG1,ERLEC1,CEP85,SRPRB,POLR2D,SNX12,CNTFR,KRT222,SMNDC1,PDP2,NEURL2,OGDHL,CAPG,TLR1,SAR1B,CCR5,IL12A,RHAG,BRMS1L,OR5B3,PAPOLA,DHRS1,HCST,FBXO34,ZBTB16,ANAPC16,CHORDC1,NAA15,SYBU,EXOC5,SERPINB6,FTHL17,WDR55,RALA,G6PD,ADK,F11R,PPP2R5A,TLR7,GAPT,VASH1,PTGES,ACADS,RNF128,ENO1,OLFM2,GNPTG,CRYL1,CHST7,SERPIND1,ORAI2,RPL24,TFPT,ALOX5AP,ELOVL6,SLC25A14,PRDX4,NUP35,ZNHIT1,MECP2,TBC1D19,CLSTN3,RASL11A,RGS6,CSTA,DCAF4L2,RPRD1B,LYPLA2,TSPO,POP7,STYK1,RNF181,CELA3B,OMG,GPD2,CYP11B2,FBXL7,LBR,PHF21A,RHBDL3,TRMT61A,CAMP,COX5A,SLC1A2,THNSL1,DUSP6,MTHFS,SETD7,PPIF,DAG1,ZBED3,CYB5D2,RPS12,TXN,MAF1,GABPB1,ARF4,SCGB1C1,RDH12,ZNF790,TAX1BP3,CALY,PML,GABARAPL2,PSMA4,DNASE1L1,SERTAD3,ZNF250,OR10A7,EIF1B,MT3,GADD45B,STX7,SENP8,MGST2,OSGIN2,NECAP1,MZT2B,LIMS2,GPC4,HBA1,PKIA,TRAFD1,TRIM35,PPM1B,TP53,INMT,NFKBIL1,CRELD1,AP2M1,TAX1BP1,PRDX6,KIN,SLC25A46,HSD17B1,TBC1D17,HEXIM2,TMED4,IRF8,RWDD4,KPNA6,PTRHD1,TOX,FCER1G,BET1,CYB561,SYNDIG1,GSTM3,TSEN34,FTSJ3,PIWIL3,IL2RG,SNX1,FTH1,ALB,CCM2,PSEN2,SLC35F1,SYK,ACO2,VPS16,CLN8,CDC42,SLC48A1,TNFAIP8L3,DUSP10,BACE1,SLC38A1,TTC23,PCBD1,AGR2,CACNB3,TMEM174,MORF4L1,NLGN1,LCN8,CPSF4,AGA,CD63,DNAJC24,AKAP1,CLEC1A,PARM1,PCSK9,PSMA6,KBTBD3,VAPB,PNMA1,CALML5,HEBP2,SP2,CASC3,SLC6A3,TCF21,CNKSR3,SEC23A,GEMIN8,MYL6,RPS9,TIRAP,TUSC2,PSMG3,GPR173,OR5V1,TOP2B,SHISA2,RAB35,KCTD10,MAB21L1,PPP1R8,CCL28,MKLN1,CMTM6,VPS26A,EEF1E1,TMEM50A,SMG8,TAS2R39,MYC,LILRB4,FEM1A,CD40LG,CD86,MANBAL,PNMA5,ENO2,OXCT1,PSENEN,SLC2A8,ZNF704,FARSA,UBE2H,KBTBD6,EXD2,CYP2R1,GOSR2,SLCO1B3,FGF23,G6PC3,RANBP6,SLC25A39,CD14,PRR5L,CCL27,ZC3H11A,SFRP1,WSCD1,ELF1,HTR1A,TMX2,RPS26,RNF40,KDELR2,DAP,DDX1,TP53I3,DPM2,RNASE6,BRIX1,IRGQ,KLHL3,CFL1,AGTRAP,PPP1R3C,CRADD,KCNAB1,APBB3,MCMBP,SEMA5A,S1PR4,TMEM11,TNFAIP1,LAMP3,CNOT6,MATR3,CHPF,REEP6,ZNF473,KIAA1143,SELL,GNL1,DNAJC2,GNB1L,ATP1B3,PPY,CRYAB,ROMO1,CYTH2,RNF11,SYNGR2,TAF7,APOC4,TLR10,WDR82,OR4S2,NAB2,FXYD6,ZBTB25,CD28,BHLHE40,MAP1S,PI16,MRPL53,HDAC3,GLRA2,RPL29,ANAPC4,ARPP19,GDPD3,TOMM40,GREM1,LRRC4B,COX4I1,FABP4,MPHOSPH6,SDC2,FAH,CAMSAP2,ACVR1B,CTDSP2,RPL10A,RAD21,RAP1B,AKAP17A,TXNRD2,DNAJB4,C2CD2L,ACTR1A,FITM1,LAT2,SNX14,AIFM1,POLR2G,COQ10B,CARHSP1,NPC1L1,TIMM8A,KLHL9,ABCB9,FAS,ATF1,POLR3GL,COX6A2,UBTD1,MAD2L2,TMPO,RBBP4,OR5A2,PLSCR3,ARMCX3,COX16,CUL3,AKT3,MAN1A2,POLD4,ERVFRD-1,CCDC92,DNAJC4,EIF3D,RBP5,CHMP2B,ELOVL4,PAK6,GRB10,CSNK1E,SKA1,RPL9,TST,DGCR8,RNF5,API5,TPH2,PHACTR1,CRYM,SAMHD1,SPRYD4,KCNS1,DNAJC30,P2RY12,FKBP1A,SRXN1,ZMAT2,NT5C2,DOLK,EHD3,ST3GAL4,MRPS18B,KCNJ8,SAMM50,ENC1,TRIM6,PYGB,SLC4A10,FOXP1,HOMER1,PDE8A,PSMB9,RCCD1,EXTL2,ALPL,SLC20A1,LAP3,ADIPOR2,EFHD1,C2CD2,CLIC4,NPTX1,COX11,MAGED4B,HNRNPH2,HMOX2,ADM2,ALDH1A3,AHCYL1,IZUMO4,TMEM108,BRD3,SURF6,FAR2,TESK1,DVL2,OR2AT4,TTC33,RPL39,MMD,WRAP53,KLHL26,BET1L,UCHL3,EEF1A1,TRAPPC4,GAS2,TFPI,PAAF1,PRKCA,SCML2,DNAJC19,VGLL4,ELF5,CLDN12,PKP4,GPR176,CHKB,CCNY,CRHBP,CNOT2,OTOS,PLEKHO1,MYBL2,ZNF326,GSTM5,ERAS,GLRX2,LANCL2,APOBEC3H,PRKACB,ASB7,FEN1,VDAC1,CLPB,KLF1,ODAM,SEPHS2,CLEC2B,CBR3,ADD1,ORC6,FLOT1,DROSHA,NR2E1,STARD4,THOC2,DCTD,FAM177A1,MCM4,SCNM1,PDAP1,SOX14,CEP19,CHMP4C,IGF1R,SLCO2B1,CX3CR1,MAVS,UBP1,KLHL22,RAB19,UMPS,CD1C,MRPL22,SS18,CDCA7L,SIAH2,CHCHD6,POLR1B,CER1,RFXAP,EPS8,UPK1A,HOXC4,BIRC2,MTM1,IFIH1,NUDT7,FCGR2B,TTL,TMEM70,MPDU1,VAMP8,PRMT6,PMM2,PPP3R2,PRSS12,TIMP3,ZNRF1,CHST13,CLEC18A,AQP2,SMAD1,KLHL24,FKBP8,GABPA,PPP2CB,SF3B5,RCL1,PPAN,IL2RA,SEMA4C,RABGGTB,FBXO7,SLC2A3,RPL23,CLLU1,SPIN3,HP,VAMP7,CTTN,STOM,CDNF,TNFRSF1B,TGFBR2,CEBPG,CAPN1,USP3,METTL22,CYP2C8,ASZ1,AR,IFI6,LLPH,GSTP1,CCL2,PPM1K,OR8B12,CGB8,TMEM45A,RNASE1,FAM43A,NLRP9,LAMP2,PTPN4,RIT1,OR10P1,GPX7,CHRNB2,MORC2,ELOVL1,SSR2,SOSTDC1,EFNA3,TPM3,SNRPB,STAT5A,COPS5,FPGT,LRRC3B,EIF4A2,OTX2,MAGEH1,FEZ1,PRDM4,MAP2K1,PLCB2,APOBEC3F,TMEM167B,HSD17B6,RNF8,PEA15,AKAP8L,EP300,ADAMTS10,GTF2H5,RPRD1A,SLC25A10,HINT3,VRTN,DDX50,PPP2R2C,BST2,STK4,SPON1,TNKS,SLC22A17,PLS3,CYP1A1,ST8SIA5,RBM38,FAM181B,NKIRAS2,ACVR1C,TMEM41A,IL1R2,KLF9,PIP4K2C,STUB1,TRAK2,SERPINB1,SRSF2,UBLCP1,GSTA1,AVPR1B,ST7,SNRK,TEX264,IFNB1,CSH1,UBL5,BTN2A2,UBASH3B,POLA2,POLB,MNS1,KIAA0513,SEMG2,CCNH,SPSB3,KANSL3,TOR1B,UGT1A1,FAM83C,MRPS9,LTA,ABCG2,MTF1,RNF148,PRICKLE2,PPP1R1A,RPL27,MSTN,CLDN9,SLC35F2,SYNCRIP,TRMT112,SLC16A10,DIO1,VGLL2,TMED5,HARBI1,PFDN2,LTB,TCEAL1,USP16,CLCN6,AK3,SLC25A12,HMGCS1,DDRGK1,PSMA1,RPL32,SHOC2,HDHD3,DRGX,CCR1,REN,DTWD1,TBC1D13,ATXN10,SOD1,NCBP2,ASTN1,SMPD2,TP53INP1,IQCK,AVL9,DECR2,FAF1,VEGFA,CRAT,TM4SF19,PTPN11,SOBP,NOTCH2,NAPA,GNPDA2,TMOD2,LRRC61,UBIAD1,GTDC1,TSNAX,POLR2B,PARL,DHRS13,RFC3,SLC7A8,GPM6B,REG1B,FBXO22,EGFL7,TMEM59L,SERPINC1,HLF,ACP5,ATP6V1A,OR10A6,OR4D2,KLF4,DENND2D,COPS7B,RNF34,ACBD6,FAM53B,PRDX1,TAF10,ATG7,NPW,NFKBIA,TUSC1,PREB,LRRC8B,ETF1,TRIM68,ADAM21,CLDN3,THAP7,UAP1,MGAT5B,PTAR1,CRLF3,UCN,PTEN,RLIM,INO80E,DEPDC1B,FRRS1,SNRNP48,ATG4C,GFPT1,SDHB,CENPW,RWDD3,TXNDC12,ABHD5,CXCL13,RORB,CKS2,EPHX1,RPA3,MOXD1,NEGR1,SIT1,FDFT1,GNG10,SMG9,MUL1,CTXN1,NRN1,MAPRE1,MME,METAP2,ZFAND2A,SEC22C,NTRK2,PABPC1,GNG12,APOBEC3G,CNRIP1,ELMOD2,OR10A4,USP15,LPAR2,FKRP,SIAE,GAMT,ISX,RTN4,GLRX5,GNAZ,DNAJB9,ARG2,RNF144B,IKZF5,FZD3,CD247,RHOBTB1,HNRNPA0,CHST2,NXT2,CTSC,NDUFS6,TMEM126B,DDX23,PCNA,PIK3R2,PDE1B,CDAN1,OPRM1,SPRED2,PLD3,AGPAT5,CREG2,PCYOX1L,ARPC3,DKC1,FBXO44,DNTTIP1,HR,LRRC3,CINP,FBXW11,CNDP2,PPFIA2,THBD,OR4D6,BCL7C,IL1A,CBLN2,NUDT12,RPL27A,TYW5,NDUFAB1,JAGN1,SNAP29,HTRA2,COX8A,LGALS8,USP8,TMEM147,PTK7,GPR171,DHX38,PGRMC1,NEUROD2,BABAM1,METTL15,GNPDA1,TMEM30A,AFAP1L2,B3GALT1,KCNJ3,COMMD6,UBL3,IRAK4,IMP3,MRPL34,NDUFB6,TMEM117,NCDN,GNAO1,CYP21A2,FASTKD5,CST11,SNX22,SFXN2,IL22,PRR3,SRSF7,EPCAM,PCDH17,STAT2,SAV1,TAGLN3,CBLL1,UBA3,GLRX,TOR3A,BFAR,TOMM22,TMEM179B,ST6GAL1,REEP3,HENMT1,RPL7L1,CSTF3,CSGALNACT2,SERPINA1,PMP22,STX11,OR2Y1,LARP4B,NPSR1,LMAN1,SH2D1A,PPP2R5E,UBB,SLC11A2,ANKRD34B,LSM10,HSPA13,DAAM1,LRRTM3,SCLT1,MRPL11,GRAP2,RAB27A,GPX1,TRIM15,RELL2,NPPC,PSMD4,RPS7,DHX15,OVOL1,FBXL14,RHEB,XCL1,BBS5,GANAB,RPS6KA4,TSPAN18,DDX46,PDHB,ZNF664,MAT2B,MLC1,OCRL,SLC30A7,TCF19,CCDC134,SLC6A6,MRPL18,MFSD5,FGFBP1,PSORS1C2,POP5,G3BP1,CHAC2,METTL21A,DSTN,DAPK3,RAPGEF5,ELOVL7,DBT,TPD52,PCDHB13,RPS27A,SLC16A1,HINT2,NUF2,OR13C8,TMEM101,CHIC2,CHCHD4,LAPTM4A,FBXL19,SUFU,MTA2,CCDC86,MRGPRX3,OXTR,KCNC1,SLC38A7,PGGT1B,RBM22,RRM1,KRAS,RPS16,KDELR1,TOM1L1,BAG3,ZNF365,OXSR1,ILF2,ORC5,CRIP1,ZMYM3,PSMB1,NR2F6,DKK1,HERC4,ASNSD1,CNTN2,IER2,NDUFAF3,CHPF2,CFC1,NLRP3,ILDR1,SHISAL2B,SCGB1D1,RASD1,CCS,SCG3,OLFM3,PPP1R1B,RND2,COMMD3,BMPR2,TOP3B,TEX12,B3GNT2,HIGD2A,TMEM91,SLC43A2,ZCCHC9,CAB39,KLK5,LIX1,DDX4,MRGPRX2,LRRC24,GRIA2,CDH8,CPSF2,OR14J1,GPX5,PCGF3,TCEAL7,GDE1,TMEM14A,UQCR11,NGB,GLT8D1,MOV10,TAF5L,MYEF2,PNPLA8,PGM2L1,ROGDI,SLC23A2,GYS1,AKIP1,SOS2,PIWIL2,OTUD7B,PPFIA3,MED11,CLIC2,SDHAF2,STX18,ELSPBP1,ORAI3,SLITRK2,CDKN1A,GK2,RBFOX2,FOXN2,LDHAL6B,CCDC65,TDRD7,CD2BP2,HMBS,RBMX2,NDE1,AMY2B,ZBTB45,ABHD13,HRH3,RAB1B,RGS5,INHA,RPAP2,OR5L1,ACTL6B,FAM168A,SNIP1,SLC4A8,LY6G5C,UBE2D1,IL6ST,TMEM59,LYNX1,RPL23A,PLEKHJ1,MLF2,ELMOD1,TXNL1,DERL2,TIMP1,SMAD3,SLC25A4,PTHLH,MRTO4,PPP2R1A,EIF4B,AP1AR,WEE2,PCDH19,RAB5C,PNP,STK38,TIMM10,CAV2,C1QL1,IFI35,PSRC1,FBXO25,CSTF2T,SLC6A11,RAB37,FOLR1,B4GALT3,ZFP1,PDYN,CRBN,SACM1L,VPS33A,CD226,GPIHBP1,WDR44,CTNNA1,RAB2A,CCNF,VAMP2,TRAPPC6B,SNRPA,CMPK1,BEND5,STAT6,SNX24,ACADSB,ISG15,OR10G7,DYRK1B,FN3KRP,WIF1,PHYHIP,RAB9B,AMT,KCNIP3,INPP4A,FGFBP2,ARCN1,EZH2,LHFPL2,SCD5,ACAP2,NFKB1,PRKAG1,HNRNPK,PAFAH1B3,OAT,MRPS28,RIOK2,OS9,RPL26,POMP,DYRK2,FOS,EGLN3,CLDN22,PPID,YPEL5,SLC35E1,CAPZA2,RB1CC1,RFTN2,TPPP,CCL8,PLA2G15,FANCG,STX6,OR2A25,MAPK1IP1L,HNRNPA2B1,ATP6V1C1,GGCT,RCBTB1,JUN,IFNG,TMEM50B,CD47,HIRA,S100A8,RHOJ,CBLN4,WWP1,CMAS,RAB23,SFT2D2,PTGER1,SUMO3,OPHN1,OGG1,ZNF687,CCR3,CRYGD,RAB33A,FAM107A,RNF167,PPDPF,TNFSF18,DNAJC8,UTP23,GNPNAT1,GIMAP2,TOMM40L,FERMT2,EIF3J,RNASEL,CHI3L1,SPTBN1,TNRC6C,KLHL15,RFXANK,PLAGL1,PAPOLB,SESN2,TRAM1L1,TRAM2,PPP1CB,EHD1,MPV17,CHST1,FCHO2,ZNF576,UPF3B,ISCA2,RABL3,GCA,TMEM106C,NUS1,SRP14,MANSC1,WDR3,GJB2,KRT7,PLEKHA8,ZNF609,TMCC2,KCNK10,SLCO1A2,TMEM164,SYNJ2BP,ACP6,APLN,TAS2R5,PTRH2,FOXS1,OR4F6,CRYBB3,ACTR2,GLIPR1,SQSTM1,RAN,RPP25,RBM12,FMO2,TMEM177,CREB1,SERPINA5,BICD2,KIAA0408,NAPG,RNF122,KCNH1,GTF2F2,DLG4,PAFAH1B2,CCL17,KIAA1191,NPY5R,CXCR4,HSPA14,BRD9,PGR,HAND2,POLR3B,CYB561D2,GMPPA,PXMP2,ATP1A2,PPP1R16A,MT2A,DDX42,SLC7A14,BNIP3L,CXCL14,ADAMTS1,CLDN8,RPL6,SPRR1B,TUSC3,CSGALNACT1,R3HCC1,SAT1,RMI2,COL1A2,SLC35D1,SMU1,MBL2,MAP3K11,JPH4,AMIGO1,TOR2A,PTS,METTL14,VAMP5,GNG2,EDEM1,UHMK1,CRTAP,ERH,ALKBH5,ADIPOQ,ANKRA2,CTDSP1,CCNB1,AKAP14,CRYBB2,NDUFAF4,TFCP2,ABHD6,CLDN1,METTL2A,OR4Q3,HTR1F,RDH10,PDCD4,LDOC1,GPAM,CREBBP,PRPF19,GREM2,TGIF2,GPX6,POPDC2,CDC42SE2,ACBD7,FAM98A,RPLP2,TRIM54,ACAT1,ZNF287,KDM4B,TMEM184B,LAMB2,SLC13A5,CLDN4,RAB3D,CXCL3,GTF2B,SDF2L1,RUVBL1,GIT2,OAS1,NKIRAS1,TOP1,TMEM144,NRSN2,GPR137,APOO,SNX17,BCS1L,MYO6,NDUFS8,CYP2C18,NKX3-1,F9,PGPEP1,GCNT3,OPRK1,BCL7B,TOM1,GPR65,TEX30,SEC61B,CHGA,TCF23,PAPSS2,TMX3,HTR5A,DNAJC22,EIF2B3,FCN2,RER1,SFRP4,RGS7BP,CDKN2AIP,CSRNP1,ATG4A,SYP,ZNF862,MRPS23,FUNDC2,HSP90AB1,POLE4,GPHN,ISG20L2,IPO8,TMSB10,CIDEB,ATAT1,ARMC7,TMEM123,DSTYK,ZBTB5,CCR2,AIF1L,ZC3H7A,FABP7,BCAP29,ZBTB17,CREB3L4,B3GALNT1,EIF3K,CD274,NAT2,KHDC1,SPECC1L,BZW2,TSPAN5,OR10G9,RINT1,TRIM5,EIF4E,TMSB4X,COX4I2,CDKN2C,CALHM3,LHFPL4,BLOC1S2,SNCG,SNAPC3,DDX39A,RAB40AL,AKAP12,IGBP1,SSU72,COMMD8,CSNK1A1,ITGA6,PELP1,IFNA10,DEFB114,MT1M,TFE3,PREPL,THTPA,SH3GLB1,RNF113A,EFNB1,GOLGA7B,TSPO2,OLFML3,RPLP0,IL10,UBE2V2,FUT9,PHYH,NTN4,RTKN,CCDC25,TES,BECN1,LMNB1,GMPPB,CALHM2,ADO,VMP1,SLC19A2,CBR4,HSPA8,EMP3,CHMP2A,OSTM1,PROS1,GPX3,TMEM204,EWSR1,B9D2,ACSL4,MRFAP1L1,TRIM24,TGFB3,CIB2,ELP3,YAF2,MTRF1,ZNF592,EED,MRPS16,ABHD14B,STMN2,RGS2,DUSP19,NME1,PDHA1,ADPRH,BCL10,NOS1AP,KCNMA1,MBD5,PCDHB1,ABHD4,BRCA1,TRAF2,RBM7,KCNK13,CDK4,NPR2,DPY30,CNNM4,NR1I2,TSN,STOML3,STAU1,KLK6,FKTN,RNASEH1,DNAJC3,TMED7,SERINC3,SLC41A3,CSNK1A1L,SOX2,ST3GAL1,IL18,DERL1,PRKAB1,DPEP1,UQCRH,CD36,IRF3,MTHFD2L,STXBP1,KLC2,PAX9,PCMTD2,STOX2,LRP6,PYROXD2,MRPS21,LCA5,STK24,RAC2,IFRD2,CEP97,ZNF501,POR,ST3GAL5,SLC32A1,PARP11,RMND5B,PGS1,RBBP7,SLC25A21,ZBTB38,TRIM37,HECW1,NFIL3,SETD5,HNRNPC,PTPN1,SPR,PPARG,GALNT12,ARFIP1,ACTA2,SIX5,TRIM21,ARMCX2,HEY2,PCDHB8,RBM17,ZDHHC14,ADRB1,PKNOX1,FRMD8,RFX4,RNASET2,SLC35E3,SPTAN1,NPY2R,LRP12,PAEP,NIPA2,RABL2B,CLDN11,FAM199X,TRAPPC1,TTC4,SCFD1,CCDC47,CACNB4,TUBG1,RPL15,GHITM,CIB3,TACR3,PRMT2,CAMK2G,TMX4,BUD31,SRP54,CCDC127,PEX3,FAM89B,RCVRN,PPP3CA,CRYGB,KCNJ11,CD200R1,FGFR1,CAMK2N1,HCRT,SHC1,PYGM,OR4K1,AGK,FBXO32,ANAPC2,SMCP,MCOLN1,PSMB5,CCT5,ENPP4,SLC39A7,SORD,SBK2,CD58,AGER,IMPACT,RAB18,FKBP14,IDH2,ZNF593,ARMCX5,PRPF4,ATF4,CTNNBIP1,GNG7,GSTO2,KBTBD2,RARRES2,GRSF1,KPNA1,PIWIL4,CSNK2A1,RS1,KIT,OR4D9,AFTPH,LSM3,SUPT7L,JOSD1,P4HA2,MMP9,BTF3,CYP27A1,S100A6,DYNC1I2,LHX2,UBAP1,ZYX,CDC73,DNAJC5,TMIGD1,PACSIN3,SLC7A9,HEBP1,ALKBH4,SNAP91,MYH2,ROPN1B,VRK1,PGK1,MFSD6L,LYG2,AAMP,GPBP1L1,MX2,SYN3,ZCCHC10,WDR77,MTPN,FZD4,MEST,ATP6V1G1,TSEN54,SERPINB10,TMEM215,FBXO42,ZNF24,MLF1,GTF2E2,CCL19,NKX3-2,MAGOH,TBC1D10C,JAK1,LBH,ABCB1,INO80C,AZGP1,HBE1,FGF1,AZIN1,PSME2,SMAP2,RAB3B,CDCA3,KTI12,NDST1,DHRS3,TNFAIP8L2,DEFB116,TLR3,GPAA1,JAKMIP1,ADGB,SENP5,CYP11B1,PYDC2,GRM2,CTNNBL1,GALNT4,IDH3B,CHDH,GNRH2,LRRC69,SWAP70,HSD11B1,CYP39A1,MYL12A,ITK,EIF4H,NCR3,FAM8A1,ZNF304,MRPL24,MRPL50,SLC30A5,KLK3,SNAPIN,RAG1,ENY2,DHRS4,SLC35A1,IMMP2L,MEF2A,RMND1,MIOS,PPP1R2,FAM78A,OSM,IL15RA,SLC38A9,IRF1,OR8B8,STRBP,ING1,P2RY1,NHP2,NAIF1,TRIM23,ARMCX1,UBE2A,CHRM4,CCT2,UBE2D3,ATP6V0E1,GABARAP,FGFR1OP2,GRPEL1,ELMO1,TCP11L2,PRPSAP1,LTBR,CASK,OR4D11,GAL3ST1,ATPAF2,KIAA0232,CLU,LMO4,CNIH4,GLUL,CDK5R1,NRP1,NCKAP1,APOBEC3A,ZNF397,ID4,ZNF319,SEC14L1,XAGE5,TAAR1,SLAMF9,ZMYND19,CCR6,POLR3H,C1QC,TRIM3,TMUB1,EDF1,ATP6V0B,TMEM219,ZNF207,MEAF6,UGCG,RPS14,LIG3,LYPLA1,ZNF671,SLC25A31,SLC17A5,CD99L2,SNRNP27,PRIM2,PDIA6,UBR7,SDR42E1,TRIM32,RNF141,KLHDC8B,PLA2G5,KLK9,ARHGAP1,DOK4,GDI2,MRPL23,GFM2,E2F6,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,EHBP1,MGP,MDM2,MRPL13,GSTO1,TMEM156,PSMA3,CCDC69,GALNT1,SOCS5,AK2,CNP,RND3,B9D1,NUDT3,LYAR,PFDN5,EXOC8,UST,GNRHR2,TOM1L2,RAB11A,PPIL4,CCNI,ASMT,CDO1,CRABP2,DPP10,PRRC2A,SF3B4,IL20RB,DKK3,FNDC8,COMTD1,DLX1,AKT1,APEH,FGD2,L1CAM,FIBIN,SNX20,TLR9,KIF2A,MIA2,BACH1,INPPL1,ING5,DEGS1,CRYBA2,POU1F1,CYC1,CCDC42,FCAR,NPTN,ARMC8,SLC35A2,ENTPD4,PTDSS1,ID1,BPGM,CDKN3,PPIB,CD164,SPEF1,OR52M1,NUP107,SCAMP2,NLGN2,DEK,SLC5A6,PRKD3,CYP4F8,CTSD,PGAP2,MRGPRX4,FABP5,NFE2L1,AKR1A1,SPATS2L,NOP58,MRPS25,RBCK1,S100A10,FAM200A,NFYA,DUSP1,TGFB1I1,BATF,TOLLIP,STX8,RAB3C,MTAP,PWP2,CETN3,URM1,CTSK,CACYBP,NDNF,DCAF8L2,ANP32B,CPT2,CHST9,WFDC13,ACOT13,TMED3,RPGRIP1L,OR2W1,CCND1,FBXO9,COX7A1,LCN6,SETD4,BMPR1A,FAF2,SCG2,ARHGAP21,RHCG,MRPL47,TMEM33,S100PBP,MPHOSPH10,AP3S2,KLF10,NAB1,ENPEP,ZMAT5,RTP4,LSM6,SYNGR1,PROX1,PRKX,FGF13,ZNF174,USP38,USP39,CERK,SLPI,FAM13B,SNRPD2,ADCY3,DCAF5,ESR2,CWF19L1,CDK6,CTNNB1,RAB8B,SOCS2,INTS12,CYP2D6,SFTPD,CLEC12B,MMACHC,TRAF7,MTMR12,DUOXA2,ABHD16B,RAP2B,TNFAIP3,TAPBPL,ETV6,RRAGA,SIRT7,IQSEC1,NOL4,FYTTD1,TSSC4,ALDH1L1,MAK16,NONO,POLL,SPRED1,H19,GFOD1,SIVA1,NDUFAF2,GPR37L1,SNTA1,SNAPC1,SV2B,HPCA,ZNF805,TCP11L1,SOST,EIF4EBP2,OR2A2,TBCE,SPATA2L,IPP,NQO1,IGFBP4,AKR1C2,NPVF,LMBR1L,OPA3,TAC1,KIF1C,GAS8,CHRNA7,CDKL2,PAOX,BRMS1,CD3G,TMED1,RBM23,BRI3,ADAT1,OCEL1,HEXA,OXNAD1,KCND2,NDUFA5,CCL21,PTCRA,TRMT6,HBB,FGF17,NEDD8,CXCR1,WWP2,RABAC1,RAP1A,ACAA2,UCKL1,CD2,POLR2I,FBXO30,TIGD7,RASGRP2,LPXN,ST13,DFFA,IL34,WNT7A,LEPR,STX17,ISYNA1,APH1A,NDUFB8,EIF1AD,NAA11,FRA10AC1,PDIA3,XPOT,CXCL1,CDC37L1,PELI3,SNAI3,NLE1,KRR1,MSX2,RPRML,SERPINH1,RPL37A,CLDN14,ZKSCAN1,HSPE1,PGBD2,STAMBPL1,SIPA1L1,OR6M1,NUDT16,LHFPL1,B4GALT6,KCNA2,HSPB1,LEAP2,HADHA,SOX21,TRA2B,DHX16,OSR2,CXXC5,CIRBP,ANKIB1,ENDOD1,SH3GLB2,EIF2B5,GALE,FUT8,GTF2A1,WBP2,NEK7,UTS2R,MOB3C,LASP1,PHKG1,SPOCK1,CREBL2,TXNIP,AQP4,GNMT,CCL25,PSMD6,IL23A,SLC39A9,FURIN,DHX9,OR51S1,ZSCAN1,WDR37,EIF4EBP3,GSK3A,PRCC,UBXN10,LDHA,PFDN6,NUBP2,PCDHA5,SLC20A2,FATE1,ATP2C1,DNAL4,RC3H2,RANGRF,ABCC5,THOC1,INTS10,SURF4,XPO5,CREB3,RNF103,TF,GJA10,SLC25A32,EFHC1,EEF2,THRAP3,XPO1,EXOC2,ZMYND11,ZNF513,SLC7A4,RNF187,GPR162,APOBEC3C,MLH3,PCBP4,APOBEC3B,BLVRA,CRYZ,FOXC2,RAB32,PITPNA,CRYBA4,PSMD1,BARX2,MPP1,ADH1B,RANBP10,MED27,SRM,BMPR1B,OR4M1,SPDYE4,TULP3,HS3ST1,CLPX,CLP1,OR5AN1,CFTR,INA,ATG3,MYLIP,FAM174A,VPS39,PTPRZ1,IFI16,SART3,PSMB10,CDK17,TMEM39A,ART5,ATP6V1D,CDKN2D,ESD,GPR37,VWF,TTLL10,ATG16L1,HDAC11,SIGLEC5,DIRAS3,TP53TG5,TPST1,ZNF200,IZUMO2,HNRNPH3,AGGF1,LCP1,PCYT1B,CSF2,PRELP,KRT8,GJB1,GCHFR,CHCHD2,SKP1,DCTN3,LSM5,PRKCB,IRF2BPL,PABPC5,HCFC2,SLC25A3,RWDD1,RBM41,COPE,CKS1B,DYNLRB2,HBP1,SEC14L5,RPL4,RGL1,SUV39H1,PREP,SHC3,CDC26,STK38L,MVD,PIGC,ARFGAP1,CYP4F22,RPL28,HCFC1R1,CACNB2,FIS1,EDEM2,SLITRK1,DDIT3,SRP72,VCPIP1,TCEA1,HM13,BCAS4,SLC39A10,MCCD1,MB21D2,LCN15,PGAP3,RNF182,RELL1,TIMM17A,SMAD9,PTPN5,LIPA,SNRPD1,CCL24,JUNB,ALCAM,IFNAR1,SDR16C5,SLA2,MARCKSL1,CCL11,RPAP3,RAB9A,RXFP2,HINT1,THOC6,PYCR1,TNPO2,PLP2,DUS4L,ABCF1,SMG5,NUP62,RNF139,DYNLL1,LYPLAL1,HSDL2,OPRL1,CCND3,STX5,RAB11B,ARL6,LEMD3,IRF4,CSRP1,TBC1D16,CA12,SLC7A1,SPATA4,CMTM7,ADRB3,FMOD,ARGLU1,EZH1,TECR,MRPL16,RNF7,MAP3K3,KRTAP4-1,ARL11,FHIT,MED29,UBE2I,UCP2,TMEM106B,MFAP1,MXD1,SLC41A1,LAMTOR2,PNRC1,PLEKHF2,SNRNP70,SERINC1,GLIPR2,MID1IP1,TDP1,SPCS1,RPL19,IL21,SLITRK5,RNASE4,DDIT4L,SAP30,FGF16,POU5F1,MSN,HBM,ZNF362,SLC6A7,MAGEB1,DICER1,UBE3A,OR5K1,PDE6D,PDZK1IP1,OR4B1,LRFN3,S100B,TNIK,RIT2,CACNG3,ZC4H2,TADA1,CETN2,CBFB,ZC3H14,EFNA5,ASPM,SH3BP4,LEP,PITHD1,SMARCE1,LSM12,FIG4,CXXC1,RPL7A,DCTN4,SEC22A,MAP2K3,DOK5,ZDHHC24,PPT1,B3GALT2,ARF6,MRPL12,FGR,SPHK2,RCHY1,LRRC14,ZBTB26,PDCD5,PRDX3,EMILIN1,BTBD10,EIF2B2,ZMYM6,ARF1,GNG11,HMGB1,PHF7,MRPS26,TUBA1B,CKB,THAP6,HNMT,ERRFI1,FA2H,KCNIP2,SERTAD1,ZHX1,GPR83,LPCAT3,ZCCHC7,PHTF2,PPIL3,CTSA,DPAGT1,CXCL10,LYRM2,FOXD3,FBLN5,MAEA,ZNF345,EID2,KIAA1958,TPD52L1,ZNF770,UBXN2B,DUSP18,SVIP,SMUG1,CDH7,ASCC1,METTL18,RSBN1L,GAD2,SEC61A1,TTR,ASB11,RGS1,SDHC,RHOG,NOL12,FAM83A,CDC42SE1,COX7B,BGLAP,STRADB,LRP3,SIAH1,NCK1,TMEM168,ST8SIA4,USE1,TMEM220,CD200,TRIM62,ZNF655,TEX19,GPR78,HNRNPAB,ZBTB6,AHSA1,PLEKHF1,SLC15A1,KCTD16,MEA1,TAF9,SCHIP1,HMGN4,CMBL,COX7B2,CDKN1B,OR6C4,NMRAL1,MAT2A,RFX5,TMEM198,TRAPPC2L,PHOSPHO2,WTAP,RPL31,SSBP2,GDAP1L1,PDCD10,LRRN4CL,NOC4L,UQCRC1,AKR1E2,CRHR1,OLA1,HAS3,PRPS1,MGST3,TSPAN3,BAD,BRS3,ZMAT3,RSL24D1,TRAF1,KCTD20,SERPINA3,RASSF4,CLK1,SKAP2,SEMA3C,DOK6,PSMB4,HERC3,DDX39B,CGRRF1,LSM4,IRF9,HSD17B8,CDR2,PTGER2,NETO1,NAA30,C9orf72,EDC3,HAPLN2,SAP30BP,AANAT,ANKH,VPS26B,YKT6,CAMKV,F2,ARL5B,ESYT1,BIRC5,MFSD3,TRAPPC3,CSRNP3,NRGN,LDB1,WNT2,GMDS,CCDC22,NDFIP1,KDM1A,PSMG2,SNN,SNRPA1,ARL6IP5,CEP70,ABHD2,CTDSPL2,GMNN,CYP26A1,ISG20,TMEM87A,RALB,NUDT1,UNC45A,FKBP2,PRSS35,TBCEL,IMP4,HELT,PDE6A,SERPINB9,MT1X,UBE2V1,TIMMDC1,RPLP1,SNX11,MET,FZD6,RETSAT,POPDC3,SLC7A11,ADIPOR1,PRM1,GAL3ST4,GFM1,EMX2,SEC61G,CENPM,SSH3,HOXB8,IFRD1,DEFB1,ACSS2,MAP1LC3B,PRSS37,PDLIM3,CTLA4,RBM5,ATF3,RANBP1,TMEM176B,CEBPE,RPL22,DLG3,RHOU,MAGEA4,STT3A,RBM3,CCDC126,RRP7A,RACGAP1,CORO1C,ARHGAP15,RHOH,HYAL2,UBE2S,ERLIN2,NPBWR1,PIK3CG,RPSA,ACTL6A,ACP2,FOSL2,GNPAT,TMEM126A,SETD3,GPR75,SYPL1,CHTOP,ZNF343,STARD7,EGR1,ZNF436,WBP11,GABBR1,ERCC3,THG1L,PDLIM4,RPF2,XBP1,TIMM13,TBC1D1,GPR34,CHRM5,NACC2,NAP1L3,CEACAM5,DRD3,MTA3,EMILIN3,CA14,DIS3L,TACR1,ARHGAP19,CEP57L1,OSBPL8,BCKDK,TRMT5,OR9I1,CYB5B,ZCRB1,MED4,NAP1L5,SEMA7A,MRGPRX1,HPCAL1,LIPT2,CD59,ECD,PRELID1,ETFA,AQP3,HS3ST3A1,TICAM1,TLR5,LCN1,RFC4,PNPO,OR2D3,COTL1,GPM6A,KCNG3,CHST10,SOX9,PRSS1,APEX1,PSMC5,GAB1,ITPRIPL2,AKT2,MMP20,GTF3C4,DNM2,OR4K13,C1QL2,PLCXD3,REG1A,CLRN2,SRD5A3,DCAF16,ALG5,DEXI,FMO1,STARD5,ABCC2,SUGP1,ACTR1B,STAP1,SMARCB1,HTR2A,TEF,ANKRD10,SCN2B,ADD2,SOD2,TCTA,PCP2,WDR12,KLF12,MLN,MAP1B,FBXO31,VSTM2L,PIGK,PELI1,CNOT8,NEU1,AMELX,VSTM4,GLO1,RAB1A,PDCD1LG2,GIN1,TKTL1,RPL18,TRAF6,ROCK2,FUBP3,KCND3,VPS72,KRIT1,RPS10,SPRY1,CCDC106,ETNK2,CLDND1,TADA3,TRAM1,ECHDC1,AP1M1,FUNDC1,UBA52,TMEM196,IMPA2,MDC1,TRAPPC6A,SP1,ITM2B,MTCH2,MGMT,SSBP4,RASSF8,CLEC6A,KCTD17,RBP2,TLCD1,AQP11,EDA2R,LCORL,LMO2,FKBP1B,PSEN1,MAGEC2,OR13A1,YTHDF2,FAM161A,ANKRD6,EIF5B,ARHGAP12,PFKFB2,SRFBP1,DIRAS2,MREG,ACER3,SCML1,TAPT1,MED10,TYMS,ZFAND6,NAA16,RPS20,RUNX1,SLC12A2,GJC1,ATP8A1,CIAO1,KIF3C,GHRL,VPS18,ZNF581,DUSP3,SUCLG2,PDE7A,CCR7,IGF1,RXRG,SNAP25,THUMPD1,GORASP2,TTC9C,GMPS,IL18BP,RASL12,ANXA4,GALNT2,RRAGB,SNRPE,DLGAP4,CMA1,GRIK1,LRRC8A,CNPY1,GNGT2,SSPN,HAUS2,OR5M9,GALC,RP9,ELFN2,LBX1,NKAP,RDH11,KCTD3,PIH1D1,BRAP,SYNGR3,TANK,MPG,DMPK,ELFN1,CDC23,MBD3,FAM151B,MACROD1,ZNF518B,CYBRD1,ADCK1,FAM136A,SLC35E4,SLC25A5,PRR13,WSB1,LYZ,TOPORS,OAZ1,FAM3C,PTP4A2,MFAP3L,SLU7,VEZT,IRF7,KLHL25,TMEM165,OR8B4,RPE,SULT1B1,TRIM26,NUCKS1,IER3,CENPL,KLRC2,TOX4,IFT172,CPNE2,CYTH4,TMBIM1,RAMP3,FXN,SUPT3H,UPRT,MECR,SGIP1,MRPS17,FEM1B,MRPL9,UBE2G2,TMEM229B,GNB3,HINFP,NUFIP2,CMC1,VAV2,CCDC3,ITGB8,BTG2,NR1I3,LRP10,PAIP2B,TRIM44,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,GNA11,SERTAD2,HSPA5,HSPB6,THAP8,WDR45,CRYBA1,MPV17L2,NRM,NPC2,TMEM115,PIAS1,PNPLA4,LRRC28,TCEA2,PARD6A,RNASEH2C,HSPD1,EIF1AX,SPG21,TIA1,SLC22A6,DDR1,TMEM81,EXOC3,SAP18,CAP2,THOC3,MX1,BOLL,PIGA,GLOD4,VPS54,SLC25A27,RBMS2,TGFB2,ATG9A,ZNF622,S100A11,RUSC2,CD9,OR1M1,IGFBP3,GADD45A,GRPR,TMEM183A,DPEP3,BTG3,PLAC1,SCAND1,PSMD7,SIN3A,CDK7,RGN,FKBPL,RAB6A,CTTNBP2,PDE2A,ZNF428,CDIPT,TNFSF8,PYCR2,ARFGEF1,MED22,NOG,PMPCA,TLR8,CD40,AIP,TNFSF15,SLC6A2,CRY1,RNASE9,GADD45G,LDB2,YPEL4,TMEM107,RPA2,RGP1,CCDC90B,PIWIL1,TRAF3IP3,SRPK2,TAB2,CPXM1,THAP1,UNC79,FBXL4,CD34,PRCP,EID2B,TMEM100,DCTPP1,OR4A47,TRIP4,RPL10,STAR,SUPT5H,PDCL,SPINK9,SLC25A24,GLCE,SSNA1,GK5,IP6K1,IL2RB,PTGFR,FBXW4,P2RY4,ST3GAL2,TAS2R7,CD209,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,TEX261,OR4D5,RNF10,POLE3,KRTAP8-1,GP9,OR51E2,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,POLR1D,GPR160,DTWD2,PSMD3,TNR,OR6X1,TM4SF18,BOK,OR8H3,SLC8A1,LSM14A,CAPN2,STARD3NL,YWHAZ,ICAM2,ABHD8,RNF222,REEP4,AASDHPPT,CCNA2,TM4SF20,GJA1,MAGED2,SLC29A1,SURF2,OR4K2,GRM1,PCGF6,TAF1D,KCNJ10,SHPRH,ADORA1,SLCO3A1,SPATA2,HOMER3,MAGEB10,CXCR3,SLC25A1,STAMBP,HNRNPF,ZNF511,EHD4,CEND1,FAM81A,CITED1,TXNDC17,ARL4D,LIAS,NPY1R,PSMD10,GCLC,TNNI3K,CPLX3,CTU1,EPHA4,KCNJ2,PSMB7,TNFAIP6,FBXW7,PLG,DMTF1,CDK12,DLK2,SPP1,FRZB,FAM149B1,CHRM3,TSR2,ARL2BP,ING2,ZNHIT6,GPR17,GPC1,PLCB1,PRSS23,DCAF12L2,PLSCR1,PTP4A3,HSPB2,COMMD9,CBLN1,STK3,LILRA2,TNKS2,LY6H,MRPS18C,NT5DC1,TRIM36,JAK2,PROK1,PAQR3,CREBZF,NDUFA1,DDAH1,GPR35,HFE,MCL1,FAM53C,GSTA2,TMEM127,HCAR1,RB1,TRIM29,CORO6,OIP5,DPH5,PNMA3,ZBED1,ICOS,NINJ1,BLCAP,ITGB5,RGL2,NDUFC2,TMEM205,TRIM34,YIPF3,LXN,TCEAL8,RPS2,CAV1,B4GALT4,CYP3A43,SPEM1,PDE4B,CCIN,UBE2L3,TTPAL,PMAIP1,EIF3G,MEPCE,HUWE1,ABHD10,CPLX2,PRND,CNTROB,FTSJ1,AKR1C1,CSNK1G3,RAB39B,MRPS11,IL2,SEC13,TNFAIP8L1,VMAC,NBN,AIPL1,PEX13,TBC1D25,TYROBP,WDR11,NHEJ1,SLC35B3,FHOD3,ACCS,TIMP4,XRCC5,SNRPG,WDR5B,ZDHHC4,CDC20,IGSF11,CYP2C9,MRPS34,ATAD1,TRIM45,DUSP21,RBBP8,MGAT4A,SGMS1,SLC19A3,OLR1,FBXO8,NDST3,MPPED2,PRL,CDC7,LZTFL1,SNRPB2,TFB1M,SUMO2,CCR4,CHRAC1,KLF3,TNF,GGH,NUDT9,CYGB,PPAT,IL17F,SESTD1,CARTPT,KLHL1,FOXA3,PARP2,NF2,ABHD12,BANF1,PHF13,RPL26L1,CGGBP1,COX6B2,TMEM170A,RNF133,ZNF451,PRKCE,GNRH1,WDSUB1,TSPAN17,PRKRA,DBR1,TAS2R13,UBE2E2,RHOBTB3,HGS,POLR2L,POLDIP3,FSTL1,MT1E,DPH3,LRRC40,CRISP1,ELK3,CD81,CRTC2,NPM3,TSPAN15,TMEM38B,NUDT2,PSD2,GH1,BAX,PEBP4,ATP1A3,FEM1C,COCH,COX6C,PICALM,LST1,XAF1,PIK3AP1,RPIA,VTA1,CNN3,CPT1B,RBM27,ZBTB39,ANKMY2,MAD2L1BP,TMEM47,LY96,AP1S2,APEX2,ADORA3,SF3B1,TAB1,AKR1B1,TMEM185A,NDUFS2,PAIP2,SNRNP40,FAM83B,PIK3CA,IVNS1ABP,CDH11,PSMC3,JAKMIP2,SSX2IP,SYNPR,BCL6,GSTCD,E4F1,TMED9,GTF2F1,DLST,SNX10,CA2,SGTA,USP6NL,MTDH,ZNF263,TPPP3,PRNP,HSD17B10,CAND1,GABRA1,TMEM89,MIS12,CBX3,DR1,HS2ST1,GTPBP8,LYPD6,ELMO2,TRPC1,ASPA,BCL9,PEX5L,MAGOHB,TM9SF1,COMMD2,FAM118B,CBX5,MYCT1,ARL10,KCNMB1,TRMT1L,GABARAPL1,CD46,GNAI2,CDC123,UCK1,RBM18,QPCTL,TOPBP1,MTG1,RPL3,G2E3,GLRA1,C1QL3,VMO1,MRPS18A,TRIM11,PROM1,YIPF4,CSNK2B,NRSN1,HOXB1,TMUB2,RHOB,OR4K17,MAX,BOLA3,DEDD,CDC42EP2,PPM1G,FLRT2,GLYAT,GFI1,TMEM209,E2F4,MRPL52,FCF1,MYD88,CD1D,PLN,KDSR,LRRN1,CD1B,GCC1,DNAJC27,DNAJB6,ZFAND2B,STARD13,B4GALT1,AOX1,PSMA5,CRKL,TGIF2LX,ATP1A1,CNPPD1,NLRP1,FBP1,GZMK,TMEM199,RP2,STX12,KATNAL1,TMOD1,TNFRSF14,TXNRD1,RPS11,KCNMB2,GTPBP1,GSTK1,NAE1,NDUFA12,NUDT5,ILVBL,ARL15,EGFL8,AZI2,PDE9A,SLC1A1,CCDC71,CYTH1,SNAPC2,SLC22A12,CCHCR1,RPS5,UBE2F,FOXP2,CYP17A1,UBN1,TPSG1,RAP2C,ADNP,LAMTOR1,DDX5,EIF4A3,CSTB,MCHR2,KLHL7,DET1,OR51A4,ZNF330,RNF14,GTF3C3,GPNMB,PRRG1,SAT2,RGMA,DNAJC10,RAF1,IRF6,ALG2,MBLAC2,PHKA1,SCYL2,RPL10L,COG1,SYS1,GPR26,IL1B,BAP1,PLAA,RPRM,FUT1,DOHH,DRAP1,MEF2C,LRRC4,LITAF,ARL4A,ARFGAP3,LAMTOR3,ZNF175,SNRPD3,GPSM3,TP53INP2,STK11,TESK2,COMT,GOLPH3L,TNNT2,ELAVL4,RPS27L,SEC61A2,TMEM106A,ANGPTL2,LY6G6C,RHCE,PHAX,BAALC,FKBP10,FGF12,SEC62,RIMKLA,EXOC1,GPX4,PTN,TMEM31,KCNA3,F10,SSBP1,NEK2,NDUFV2,ZNF526,NDUFB7,PC,RAB5A,RAB14,BVES,GOLGA7,TMCC1,REP15,WASL,CD79B,SDC4,SP4,ZBED4,OR4N4,DYNLT3,TLR6,CD151,RPN1,KCTD9,DLG1,P2RY11,IL3,CHRM1,MSX1,DPP4,PRDX2,MRPS33,LMBRD2,LMO3,EIF2S1,UGP2,PAX6,STAT1,ZNF507,MOBP,PKIG,MAMDC2,TSG101,ADCY2,DRG2,THBS3,TRUB1,SNAI2,CALR,SHMT1,HEXB,SYNGR4,PPFIBP1,CYTL1,NDUFA4,SLC45A3,OAF,FNTB,NME4,SLC6A4,PDSS2,YIPF5,TOB2,SFTPC,SLC25A23,ODC1,DSN1,ZC3H15,CYB5R3,PLAC8,RPP21,SNAPC5,NDC80,RNF26,RAB13,OR10G2,MAP1LC3A,CDK5,GNG3,MRPL51,PATE2,STXBP6,TPBG,KCNQ5,DAPK1,PDE1A,LILRA1,NFYB,SLC25A17,LRWD1,ZCCHC12,ARRDC3,SESN3,CDSN,ZNF692,SLC25A44,PSMD14,THY1,YWHAB,TESC,EDNRA,TBC1D24,ST6GALNAC3,LEPROTL1,TMEM95,SPOPL,SYT2,MMADHC,TTC1,NR1H2,BMP1,PRPF31,TXNL4A,USP14,TSC22D3,NANP,CXCR6,GNA14,CISH,EIF2S2,ZMYM4,BTG1,AGPAT1,ASB3,CHMP5,HDAC6,PBLD,RNF39,ANAPC13,CNTNAP1,TMEM176A,DUSP26,EYA3,ACTL9,GTF2A2,GPR15,COPS7A,PPARA,RNF20,MICB,TOR1AIP2,NUP153,STOML2,OTUD6A,RERG,POLR3F,RPL35,FRS3,RRAS2,TPT1,SNCB,ATL1,RASL10A,METTL6,IFNA2,IDH1,TUFM,OR51M1,GNG13,VPS28,MPZ,KRTAP12-4,CD2AP,SRC,PIK3R3,LANCL1,MORC4,CISD1,SLC35B4,MKKS,TERT,PTGER4,TOMM20,TRAF3IP2,BAHD1,DHRS7B,IZUMO1,PEG10,ZCCHC17,PSMB6,PIP5K1A,CHRDL1,CKLF,CCT7,PSMD12,KCTD15,PAFAH1B1,SLC25A11,PDCD1,MS4A7,SECISBP2L,RAB33B,IFIT2,CDC42EP3,RNF115,MCM3,RCE1,MGAT1,RASGRP3,ENTPD3,RGS19,RPL7,TUBA1A,YTHDF1,NAA50,FCGR2A,CELF6,SH3BP5L,MED31,LUM,CCDC85B,SEMA6C,NEUROG2,MTMR6,UNC50,ICAM3,HMX2,CHST11,TNFSF13,FLRT3,STIM1,GRPEL2,FTL,TMC7,LRIF1,SERPINI1,IDO1,PPM1D,KLHL12,FLCN,CXCL12,MSL2,SLC25A28,SLC39A3,RSRC1,RPL35A,CD248,ZNF668,CCL20,MRPS7,ZNF575,ARHGAP5,VTI1B,SPATA6,GLT8D2,EIF4E3,MYOZ3,TCAP,ARHGAP25,DES,RIC3,LIN7B,PCDH9,ZRANB2,SCPEP1,OGN,TMEM190,NSFL1C,POLR2F,PADI2,NDUFB10,POMT2,LRRC57,PLSCR4,MOG,SCN3B,NMI,OSGEP,NDUFA2,RIMS4,NUP50,IFNGR1,HMG20A,BTF3L4,TLE1,ARL6IP6,PNOC,CYP27B1,IL15,MRPL10,YBEY,NTPCR,TMEM14B,GNG5,NIF3L1,UTS2,RRN3,DHPS,SMARCA5,CNPY4,DRAM1,IL1RAP,VKORC1L1,BAK1,ATP1B1,ELK4,FAIM,GPR85,PPP2R3A,RILPL2,FZR1,DRD1,SMAD4,SLC22A8,SLC1A3,LRRC1,NUP37,TCEANC2,TM9SF4,GPBAR1,ITGAV,USP5,MXI1,FERD3L,FOXP4,RNF126,TMEM182,LDHB,RPF1,FXR2,AKR7A2,AURKAIP1,AGAP1,UBE2M,PIR,SLC6A12,TRIM10,UBE2E3,OR5AP2,MOSPD1,ELAVL2,ISCU,FCHSD2,GTF2E1,TNNC2,OR8I2,SMC4,RAB22A,AK5,CLVS1,FAU,KBTBD4,PNO1,CYP2F1,PSME1,PSMC1,PAIP1,SSRP1,TTC32,TWSG1,OCIAD2,MED21,RLN2,OR9K2,HPGDS,NDUFS3,DNTT,OSBP,GOLGA5,MORN4,GIMAP4,RPAIN,TBC1D4,UNC119B,GABRB2,ARMC1,SYVN1,HSCB,CES5A,TFEB,GRID1,PPP1R12A,CCDC122,IL6,RERE,TLR2,FGF10,HECTD1,DYNC1I1,LGR4,UBFD1,GSTM2,NAA35,PPP4C,PPIG,NRBF2,EFHD2,GGT7,GRXCR1,DNAJB2,PSMA2,NICN1,TMEM208,RAB30,RSAD2,GABRA2,COMMD5,SST,PFDN4,CNR1,CAMLG,PLA2G12A,NPY,MFN1,ZBTB2,DAD1,TAS1R2,LNX2,SNX18,TYW3,RFC2,GNB4,CPNE1,ZER1,CNTN1,ACTB,MATN4,DDAH2,UGDH,PGAM1,AP2S1,RNF121,RPS13,EPO,CHCHD3,NFKBIB,MMP21,ZNF280B,EID1,HDDC2,LPAR1,CD1A,HSP90AA1,DCUN1D5,FNDC9,PPIH,FOLR2,PDRG1,PTPN22,SOCS3,NOVA1,INPP5K,MCAT,SEC63,NUDCD3,TM4SF1,IRF2,ERP29,PTTG1,BCCIP,CAMK1,WFDC5,NOL7,SNX2,TACO1,NSA2,SSBP3,NXPH3,DEFB115,REXO2,DTD1,POC1B,NTF4,GPHA2,CYB5R1,LRTM2,MYT1L,USP2,SLC39A13,CPE,CYP4F12,DCAF4,ARHGEF6,PCSK2,SCN1B,CDC40,NELL2,TM2D2,NDUFB5,SUB1,OR52W1,G0S2,OR5I1,TRA2A,SATB1,PRMT5,BEND6,ACO1,GANC,RALGAPA2,PPTC7,PCK2,SFXN1,UBAC2,UBXN6,KCNF1,CD4,NR4A2,SLC25A45,NOSIP,LIMD2,TRIM27,COPS2,C1GALT1C1,LGI3,EIF2AK2,GTPBP2,TSHR,SLC25A20,EIF2D,AIG1,NEUROD6,INSM2,RAB31,OR8K1,STC1,DYRK1A,DRP2,SRGN,KLHL32,TMEM74,TIMM8B,IRAK1BP1,CYP3A5,CD52,PHF1,LMNA,DCUN1D3,DCAKD,PLP1,XPNPEP1,RNF41,ZNF7,MGAT4B,EXOSC4,BUB3,SLMAP,CFL2,SNX5,ZMYM2,OR4N5,KLRD1,FASLG,MSRB3,EIF3E,CTBP1,CDC42EP4,DDT,JUP,ALKBH3,EXT1,MT1A,CD38,PNMA2,ANKRD49,CUTA,DLAT,RMI1,CAMK2N2,RIMS3,GRM8,EIF4E2,IL13,MCM8,UTP15,OSGEPL1,HP1BP3,PACRG,TAS2R16,TLCD2,PHF12,GEMIN7,ZBTB33,BAG2,MED17,DCP2,TMEM184C,NOB1,GRAP,EPYC,SELENOT,TAAR6,BLOC1S3,PHC1,PLXNC1,UGT2A3,STBD1,FAM110B,THAP2,TIAM1,IL4,TRIM63,PAQR9,TRIM46,GPX2,HCLS1,DNAJC1,EHHADH,GLRB,OVGP1,EMP2,LILRB1,CHID1,DISC1,RBFOX3,SSR1,AVPI1,SMARCD3,NETO2,MCHR1,SFN,ZNF596,SF3A1,PSPC1,GNAI3,TRAPPC10,FAM50B,STX10,TUBB,LSM14B,COIL,ZFP64,CUL2,PYCARD,SLC6A8,GHR,MED30,CXCL11,TREML1,SOCS4,MED9,ASB8,ORMDL1,INPP5E,CDC16,GNB1,GLTP,SEPHS1,ANAPC11,LACRT,TOMM7,RASGEF1C,PCMTD1,MAD2L1,CA10,MAP2K6,GSTA4,RHBDD3,RBM42,PPP5C,FOXP3,LDLR,OR7E24,VPS4B,TMEM160,TMEM88,CLCA1,CNOT6L,MRPL40,CD1E,GTF2IRD1,TRMT11,SMCHD1,ZSCAN5A,VSTM2A,B4GALT7,GABRG2,TFIP11,MEF2B,WASF3,PRKCQ,RPL8,IKZF2,CLEC9A,PGM1,NAT9,HADH,POGK,SLC16A4,TRIM52,ACOT8,HNRNPA1,LECT2,NFE2,LRTOMT,SKA3,RPS29,ALKBH2,CTSB,DEFB121,NCKIPSD,COX19,SOX3,TMOD3,RPS4X,ZDHHC15,MAP3K12,RSPH1,PPIA,FBP2,CLVS2,VAMP3,WDR83,VLDLR,CRB3,DHRS7,CYB5A,TFG,ELOVL3,MTX2,MAEL,RNASEK,BSCL2,CDK8,IQCF5,PHF23,COX10,HRAS,WDR20,SYT4,TAGLN2,RPP14,RPL13A,TRIM8,FAHD1,IKBKB,HELLS,MITF,HTRA1,KIF3B,ACTN4,GATAD1,RGS10,PTGES3,ASB1,RPS15,FBXL3,QRSL1,VIPR1,PSMB11,HSP90B1,TCOF1,LRAT,RETN,MCPH1,NKRF,EDDM3B,ISOC1,ZDHHC8,KLHL28,TPPP2,EDEM3,EGLN2,LRRTM1,RNF152,UQCRC2,MRPL33,CXCL9,RBPJ,MRPL17,DUSP9,CFDP1,ATP2B4,IFNK,SIGMAR1,PAQR8,PPP1CC,OR7D4,BAZ1B,PEX26,OR4E2,NOP16,ZNF32,KCNB1,TNFRSF9,LRRC8C,DMAP1,SCAMP5,CST3,PLEKHO2,LYZL4,BCL2L1,YWHAG,ICA1,VDAC2,DCTN6,ACVR1,MYH1,IFT57,B2M,TIFA,SASH3,TPRA1,CASP4,SLC15A2,SLC52A3,TRIM22,CYB5R4,SPOP,DEFB129,MRPL36,NR0B1,AMACR,ITM2A,DCK,EAF2,ADH1A,DCUN1D1,MCM6,RPS24,NUDT4,CYP7A1,SDS,DIRAS1,GINS4,PRRT1,ABCE1,VDR,CTTNBP2NL,IL5,PTGDS,TNNI1,ADRA1A,PSMB2,FGF22,CX3CL1,CBX7,COL3A1,PAK1IP1,VAMP1,ADRB2,MYO1B,QSER1,SLC2A1,SRSF12,GPT,GPN2,SLC6A1,TLR4,P2RY10,NKX6-2,HS3ST5,PLAC9,SLC38A2,GPR22,LIN7C,SSR3,PFDN1,TAF2,SGMS2,NCSTN,ANXA7,PRR19,ANO3,UBE2N,CCL1,NGDN,CTRB2,STX16,FKBP4,PSKH1,DPPA2,PMP2,PI3,EIF5A2,SMURF1,LGI1,CDC5L,TMEM19,SLC35A5,HPS6,OR2F1,CH25H,CRMP1,TCP1,KCNH8,CNOT7,RABIF,ADRM1,CD80,TAF11,EMX1,PKIB,UBTD2,HNRNPL,IREB2,USP46,SMAD2,PITPNB,POLR2C,GNAQ,LPAR6,CCDC167,NGRN,DBNDD1,RAD1,GIPC3,NFE2L2,NCOA5,RUVBL2,IGF2BP1,GOSR1,PPIC,MMAA,SIKE1,NDN,ARMC6,CHCHD1,SNX3,TBC1D5,DBH,CLRN1,LHB,DEFB124,INSIG2,CBL,HSDL1,KLHL23,WDR6,ACOT6,IL12B,ANGPT1,NCALD,COPS4,KCNK17,RAB28,COX17,DDI1,CYP1B1,MDH1,ELK1,FAM168B,RALYL,MRAS,MRPL41,MRPS35,ATP6V1G2,MMP14,RAB6B,SRSF1,ITGA2,SLC31A1,DIO3,COX6B1,LMBRD1,UCK2,FGF7,MAPRE2,CAV3,EPHA2,PRPF18,CDK2AP2,IGSF21,IFT52,PIK3R1,ACOX1,F7,FADS2,KDM2A,POLD2,KLHDC8A,EXOSC8,ZNF574,SUMO1,DCLRE1C,G3BP2,OR10G3,OR2J3,PDIA2,SAP30L,RNF146,SNAP23,FAM76B,BOLA1,ELOF1,PAQR4,GGCX,CCAR1,PICK1,NTRK3,TSSK1B,GUK1,STX1A,AGAP2,FBXO3,IRF2BP1,ACHE,UBE2B,CSE1L,OR4N2,FAM3A,MNAT1,STAC3,NEK9,FMO3,TNFSF10,CDK5RAP3,CLDN6,CAPZA1,GAPDH,CBLN3,CRYGA,CLIP3,VAC14,SLC25A42,YES1,GRIA1,PI15,HECTD3,HDAC5,FABP12,FGL2,UBL4A,SERPINB11,RPL17,GKAP1,ASRGL1,POU3F4,MFSD6,MADCAM1,MPST,PSMC4,IDH3A,JRKL,RFC5,TMEM97,NSDHL,MED13L,SLC35C1,NXT1,RLN3,ANKRD50,NEO1,ESAM,PCCB,HSD17B3 |
| 2.880e-13 | -28.88 | MSN (moesin) | protein interactions | 4478 | 289 | 139 | 19454 | 5460 |
VIRMA,ROCK1,SMURF1,MSN,GANAB,ENO1,CTNNA1,CALU,CDC73,STK24,ARHGAP21,MAT2A,CTSD,AATF,MARS1,HSPA5,FBXW7,NUCKS1,PPP1R2,LCP1,MNS1,PGK1,SIRT7,RPA3,BAP1,METTL14,FGFR1,JUP,RPA2,CD46,CFTR,CD2AP,FAXC,GTF3C4,UBA52,ARHGAP1,CAPN1,ATG16L1,CAV1,CDK9,CD151,CAND1,SEC23A,AKR1B1,CD274,PTPN1,HRAS,GAPDH,HDAC6,CD81,ISYNA1,EMC4,CALR,CAPZA1,L1CAM,HSPE1,HNRNPK,HSD17B10,IGF1R,ERO1A,ABCE1,RAB1A,NAE1,NUPR1,PSMC3,CAPN2,NHERF1,H2AX,TP53,APEX1,SELL,DYNLL1,TUBB,ACTB,ATP5F1B,TAGLN2,STAT1,ENO2,ICAM1,BRCA1,RHOB,PSMD14,FAS,CUL2,PSMA4,LMO2,MYC,GINS3,RNF11,PAFAH1B2,NSFL1C,UCHL3,HADHA,HSPA8,ARCN1,PIH1D1,ACAA2,PPARG,MRPL12,YIPF5,PAFAH1B1,NOTCH2,SYK,DHX15,PRKCQ,SPTAN1,TRIM15,FABP5,HSPB1,PPM1B,CTNNB1,XPO1,HNRNPA1,ICAM2,PRDX1,LAMP2,IMPA2,PSMD12,FKBP2,PFDN1,RUVBL1,KRAS,ICAM3,EWSR1,HNRNPA2B1,CHMP4C,NME1,PDHA1,EZH2,PLS3,TRAF2,SOX2,MAPK10,ISG15,PPP2R1A,E2F4,ARFGEF1,FASLG,B3GNT2 |
| 3.033e-13 | -28.82 | MRPS5 (mitochondrial ribosomal protein S5) | protein interactions | 64969 | 316 | 149 | 19454 | 5460 |
EXD2,NGRN,LCN1,NOP53,MRPL57,UFL1,HSCB,MRPS7,PSMC1,SYK,TIMM29,MRPS18A,MTG1,CCDC90B,TACO1,RPS9,RPF1,RPL35,MED17,RPL10,DES,RPL19,CUL3,PMPCA,MYC,MTG2,AUH,PSMD1,MRPS25,RHOB,PSKH1,TAFAZZIN,ZMPSTE24,MCAT,RIT1,HSPD1,SRSF7,COX8A,MRPS11,HINT2,NUP42,KRAS,IMMP2L,FLOT1,SRSF4,MRPS17,PSMD12,ZNF263,TULP3,EEF2,PPP2R1A,SOX2,PDHA1,RPL18,SRSF1,FBXO32,GATD3,FAHD1,CORO1C,KCTD10,RMND1,CHMP2A,MRPS35,RPL6,MTRF1,TRA2A,EIF3D,DDRGK1,HNRNPA1,RHOG,MRPL18,SKIC8,RPL23,LHX2,MRPS26,BAP1,GFM1,PRKCB,FBXW7,RPL4,SLC25A51,CRYZ,KLF12,RBMS2,CDC42,MRPL10,MRPS34,MTRES1,KLF4,ZNF574,TMOD1,DYRK2,HEXIM1,SNX3,RHOJ,RPL13A,MRPS21,SMURF1,TUFM,RPL26,ATP5F1A,DNAJC19,UBE2H,ZBTB38,CLPB,MRPS18B,MRPS33,H3C1,SNRPG,GALNT2,RPL17,FASTKD5,MRPS18C,MEPCE,MRPL11,TP53,ATP5PB,METTL15,APOBEC3D,AURKAIP1,MRPL36,TAF2,GFM2,MRPL33,ACTA2,ALYREF,SRP14,SDHB,SSBP1,MRPS9,RAC2,PRR3,TRMT10B,CGAS,EIF2B5,FZR1,CAND1,MRPS23,MRPL24,ZBTB2,RBM42,MOV10,GRSF1,E4F1,SNRNP70,CHCHD1,TMEM70,DNAJC4,NOL12 |
| 3.118e-13 | -28.80 | RPL32 (ribosomal protein L32) | protein interactions | 6161 | 308 | 146 | 19454 | 5460 |
G3BP2,EMC1,UFL1,STAU1,RAB5A,PIH1D1,EMC9,RPL27A,RPL10,RPL19,RPL35,RPL37A,SEC61B,MRPL13,RPS9,FAU,CMTR1,HSP90AA1,RPS26,RIT1,NSA2,RBBP8,BRCA1,BTF3,RPL39,THAP7,MYC,CUL3,RPS4X,RPL28,EMC8,KRAS,G3BP1,TMEM147,RPS11,SLC1A2,SART3,RPS23,RPL18,CHMP4C,PDHA1,MAK16,OTUD6B,RPL29,B3GNT2,MAGEB10,HSP90AB1,RPL7,LYAR,RPL8,RPL9,FOLR1,PHB1,SRSF1,RPL23,DRG1,AGR2,ATG7,MAP3K14,DDRGK1,WWP2,RPL6,AATF,LSM8,NPM3,RPS15,RPL4,HMGB1,NUCKS1,RNF113A,PPIH,RPA3,BAP1,RPL27,SNAPC1,PRPF4,RPLP0,RPL26L1,RPA2,HBB,ZCCHC17,CFTR,RPS14,UBA52,SRPK2,RPL22,RPL13A,FGFBP1,PRKRA,GSK3A,RBMX2,RPS20,PTEN,CCNF,RPS3,METAP2,PTTG1,UBE2H,CALU,SPOP,MECP2,EIF3G,RC3H2,RPL26,TUFM,PPP1CC,RPL7A,MEPCE,RPS13,RPL17,CTNNBL1,H3C1,LSM4,VRK1,RPL3,RPL23A,ABCE1,SNIP1,HBP1,SRP72,RBM34,DNAJC2,AURKAIP1,RPL15,UBL4A,FBP1,RPSA,PTP4A3,MRPL24,CAND1,RPS16,RPL35A,FZR1,SPPL3,RPL12,RCHY1,ALYREF,RPS2,RPL10A,RPL24,SNRNP70,HDAC6,COPS5,ENY2,GRSF1,EMC4 |
| 3.165e-13 | -28.78 | TRIM14 (tripartite motif containing 14) | protein interactions | 9830 | 379 | 172 | 19454 | 5460 |
HEXIM2,RTRAF,ENO1,STUB1,CEP97,NONO,USP14,PYCR2,PIM2,IVNS1ABP,MAVS,GID8,RPA3,PRIM2,VPS28,SMC4,COMMD3,TIMMDC1,PSMC4,HNRNPH3,RPL26L1,DCTN4,JUP,EIF4E2,ACTA2,HACD3,SRP14,ZNF652,MRPL24,G6PD,CDK9,MAPRE2,CGAS,RPL35A,ATP1B1,ISYNA1,ERCC3,NFKB1,HSD17B10,RPL23A,SFXN1,SLC25A10,RIGI,MSH6,PRDX4,RPS13,RNF20,H2AJ,TBK1,DHRS7B,RAD23B,PPP4C,POLR2G,UBE2B,SNRPD2,RAN,RPL19,CHCHD3,ITM2A,TSN,DYNLL1,RBBP4,MCM4,PRPF31,SAMHD1,PYCR1,CUL3,HTRA2,BAX,EXOC8,HADHA,UNC45A,G3BP2,NSFL1C,SRI,IDH3B,PPP1CB,AGTRAP,KCTD12,PSMB7,PSMB5,RPL9,NPC2,AGK,PRPF19,PSMD3,HNRNPD,AHSA1,HAX1,PSMD10,MAEA,ZYX,PCGF6,SRSF4,MCM6,RBBP7,ERLIN2,RAF1,CKS1B,SF3B6,GMDS,MTPN,ETFBKMT,BICD2,EIF3G,ATP1B3,PRDX6,RAB9A,SEPTIN6,STK38,RPS15,CAPN1,ALYREF,UBE2N,CAND1,TSNAX,AKAP8L,SLC16A1,SLC25A11,MNAT1,AKAP12,ATP5PB,PSMC3,CBX3,PRMT5,SF3B4,PSMB6,TAX1BP1,PSMD4,UFD1,BAG3,MLF2,PSMD1,HNRNPC,SERPINH1,ATG3,LAMTOR1,RAB5A,HERC3,FAM50B,BOLA2B,STAU1,SSR3,HNRNPA0,SRSF2,PSMB3,RPL27A,KLC2,HDHD5,CIB3,SNRPA1,DYNC1I2,EIF2S1,DDX50,GSTM3,ARMC8,DRG1,HSPB1,NCK1,PDIA6,RPL31,PSMA1,PSMA2,HNRNPF,RPS7,SPG21,TRAF2,RANBP1,CRKL,SMARCB1,MTA2,ZC4H2 |
| 3.301e-13 | -28.74 | AURKA (aurora kinase A) | protein interactions | 6790 | 683 | 278 | 19454 | 5460 |
SEC61G,PNMA2,TUBB4B,UBL5,ERRFI1,EEF2,H1-3,PSMA2,HNRNPF,PSMA1,KRAS,HNRNPDL,RPS4X,DCTPP1,UQCC2,GSTO1,IKBKB,CDC23,IFI16,CNOT2,CTNNB1,UTP6,NGDN,CPEB1,XPO1,CNOT8,AASDHPPT,RPS10,HSP90AB1,FEZ1,FUBP3,KCTD20,MAP2K1,PSMB3,PITHD1,SLC31A1,EMC1,SOX3,PEBP1,SNRPA,DDX5,HSPA8,H2AZ2,RBM27,S100A11,MDH1,MYC,MATR3,STAT2,APEX1,ZNF189,NFKBIA,MRPL13,GTF2F2,DKK3,CBX3,CDK8,TFCP2,BIRC5,TP53,TNRC6C,SRFBP1,PPP3R2,ESS2,ACTR1A,MECR,TOLLIP,RPIA,MSANTD4,HNRNPK,H3C1,PSMA5,DHX9,SNRNP70,TUBG1,AKAP8L,TAF9,USP2,COX5A,ZNF24,ENY2,CSNK2A1,RPS16,FZR1,SURF6,NDUFB4,UBE2N,RAC2,PREP,STX17,HBB,ZNF326,RPA2,ACACA,HECTD1,KLF4,HEXIM1,GSTP1,AKR7A2,IGFBP3,GTF3C4,HSPA5,PML,PSEN2,RPL27,LSM12,HNRNPH2,ELOF1,RIC3,SPOP,CALU,RRP7A,PTTG1,IGF2BP1,AKT1,NAA50,TNFAIP3,SLC35B4,CHMP5,GPX1,EIF4H,SRPK2,CDC20,PSMA6,RPS3,NME1,SART3,EIF1AX,RPS11,ARFGAP1,GFI1,ASPM,TRMO,G3BP1,COPS4,SSRP1,ANP32B,HNRNPA2B1,GADD45A,HSPD1,NEK9,HECTD3,DICER1,BCL2L1,RPL23,HNRNPD,LYZ,CDH13,PTPN5,NDC80,MAP1S,MRPS35,HNRNPA1,ATXN10,SNX18,NOP58,NUF2,WIF1,NTMT1,SRSF10,EGLN3,CNTROB,MRTO4,PPP2CB,PSMB5,RPLP2,LARP4B,PSMB7,SLC25A3,PSRC1,PPP1CB,TIMM13,RFXANK,NOP53,UCHL3,FBXO30,SKP1,FTL,DCTN3,BRCA1,RHOB,RIT1,LSM14B,HSP90AA1,KLK5,RPS5,CUL3,USP13,MRPL16,OTUD7B,DYNLL1,TSN,RPL35,TUBB,USP5,OTUD6A,MAD2L1,EIF3K,SEC61B,SNRPD1,JOSD1,SOD2,ILF2,MTA3,AURKAIP1,EEF1A1,MAP2K3,TOM1,THRAP3,TTC4,CTNNBL1,CNOT7,MDC1,PRDX4,PTGES3,CTNND1,TCOF1,MPHOSPH10,CRBN,FOXP1,NFKB1,GLO1,GTF2E1,HDAC6,MAPRE2,NAT2,MRPL24,MDM2,CITED1,NCBP2,PTP4A3,EIF4E2,RPL12,ETV6,PSMB1,FBP2,PAK5,RPL26L1,RPLP0,SPR,TPT1,RPS14,FTH1,SYNRG,FAXC,FBXW7,PIK3R2,NF2,AATF,BRIX1,MBD3,SIRT7,PPM1G,RPA3,DVL2,EGFL7,SPCS2,ARPC2,MYT1L,SQSTM1,ASCC1,MAPRE1,EPHA2,STK11,CDC16,PPP1CC,GMNN,GMPS,SNX3,RHOJ,CEP97,RPL22,UBE2L3,UBB,SFRP4,TMSB4X,UBE2I,TRIM27 |
| 3.361e-13 | -28.72 | RUFY1 (RUN and FYVE domain containing 1) | protein interactions | 80230 | 466 | 203 | 19454 | 5460 |
RPL18,RND3,MTA2,RAB4A,TUBB4B,RPS7,EEF2,TUBA1A,UTP25,RPS4X,RUVBL1,HNRNPF,OAS1,MYO1B,CCT8,RPL31,HSPB1,FOSL2,XPO1,RAB5C,LAMP2,CCT7,HSP90AB1,DYNC1I2,RHOH,TCP1,RPS10,MAGED2,RAB35,GLRA2,RPL27A,PHB2,EEF1G,RAB5A,HSPA8,XRCC5,H1-1,SERPINH1,RPS26,H1-10,LAMTOR1,CCT2,PCCB,LDHB,RPL10,ESR2,FBXO22,ATP5F1B,MATR3,PHF21A,PRMT5,PSMC3,CAPN2,RPSA,KBTBD4,CAPZA1,FKBP8,HNRNPK,SRPRB,CSE1L,KPNA2,TMEM33,DHX9,RPL3,MRPS18B,SLC25A11,RPS2,RPL24,MYL12A,TMPO,RAB39B,CAND1,RPS16,RAC2,COMT,ACACA,GIT2,NTPCR,CDC42,HSPA5,MARS1,ST8SIA4,KDM1A,HDAC3,RAB9A,HNRNPH2,TXNDC17,ATP1A1,IGF2BP1,TRIM23,CFL1,H2BC9,RPS17,MORF4L1,RAB2A,SLC25A1,ROCK1,PSMC5,RPS3,PLD3,SART3,RPS11,NGB,RPN1,PPP2R1A,FAF2,AP1M1,RPS24,SLC25A5,HSPD1,RPL23,RHOG,VPS26A,STOML2,PSMD3,PRPF19,PRDX1,DHX15,NTMT1,NDUFS8,ATXN10,CCAR2,RPLP2,XPO5,PHB1,RPL9,MYL6,SLC25A3,RNF7,RND2,PGRMC1,WDR77,H1-5,SKP1,PSMC1,STX7,HADHA,EXD2,HSP90AA1,YWHAZ,BRCA1,FAS,MCM3,GGH,RNF40,RAB11A,CUL3,RBBP4,TUBB,PRDX2,RPS9,RAN,PELO,CD79B,SRP72,ILF2,NDUFS3,LBR,CCT5,MSH6,PRDX4,TTC4,FARSA,HUWE1,PC,RPL23A,SFXN1,DNAJC7,FAM53B,NME2,LRRC40,KXD1,CAV1,MRPS23,EEF1AKMT3,ACTA2,HACD3,RPL12,AIFM1,RARS1,RPL26L1,RPLP0,HSP90B1,TIMM23,CDK1,CNP,UBA52,ATG16L1,RPS14,RPL4,CSTB,XPOT,TUFM,ATP5F1A,VIRMA,COPE,TXN,RAB14,LDHA,ASPA,RPS20,STUB1,CCNF |
| 3.403e-13 | -28.71 | PRC1 (protein regulator of cytokinesis 1) | protein interactions | 9055 | 959 | 370 | 19454 | 5460 |
GNG12,RPS9,SNRPD1,PRDX2,EIF4A2,ERH,USP5,RPS29,PRPF31,BRCA1,CNIH4,RPS5,EMG1,NOTCH2,USP39,RPL9,RPL8,RPLP2,BRD9,NUP35,DHX15,PPIA,SRSF10,PDIA3,HMGA1,HNRNPA1,WDR12,HNRNPD,MAEA,HNRNPA2B1,HSPD1,SRSF7,BAG2,S100A10,SSRP1,FLOT1,TOMM7,ACTN4,RPL29,PPP2R1A,FAF2,RPN1,SNRPE,RPS11,POLR2D,CTTN,CINP,RPS12,TMOD3,DEK,GNAI2,VIRMA,RACGAP1,RPL26,AP2A1,FBXW7,PDHB,BRIX1,TXNL4A,SF3A1,CCNA2,COX6C,HNRNPH3,RPL26L1,KRR1,RPL12,EFCAB7,CGAS,THOC1,RPL35A,PID1,POR,SFXN1,PPP1R12A,RAB1A,RPL23A,NOC4L,DNAAF10,B4GALT7,CCT5,EXOSC8,NDUFS3,VDAC2,SMU1,MATR3,RPL10,ESR2,CBX5,HNRNPC,HNRNPAB,APOBEC3B,MYC,SNRPB,PSMD1,BTF3,CCT2,SERPINH1,RPS26,SPECC1L,RPS28,DDX5,SF3B1,PHB2,EEF1G,FXR2,TRA2B,SRSF2,TOMM22,MRPL12,PABPC1L,SNRPD3,SUMO2,RAB1B,RPS10,HNRNPL,HSP90AB1,RPL6,WWP2,DDX50,BAZ1B,DDRGK1,QPCTL,CTNNB1,YWHAG,CRTAP,DDX1,ABCF1,RPL31,RUVBL1,HNRNPF,RPS4X,RPS7,NUP37,EEF2,H1-3,H2BC1,PDHA1,PTRH2,TUBB4B,RPS23,UQCRC2,MACROH2A1,CCNB1,RPL7A,SMARCA5,CFL1,CFL2,BICD2,GLOD4,MECP2,IGF2BP1,DDX46,RPL27,WDR3,RPS15,LUC7L3,CYC1,TFIP11,ALYREF,RPL32,RPS27L,FZR1,COX5A,GAPDH,ROGDI,H2AC4,RPL24,DHX9,HNRNPK,NUP107,H3C1,RPL17,RPSA,ATP5PB,STRBP,IMP3,CAPZA2,CBX3,BIRC5,NUPR1,RAN,CDC7,RPL37A,RPL35,RPL7L1,RBBP4,SNRPB2,RPL19,CHCHD3,CUL2,NOP16,MCM4,TOMM40,RFC5,LMNB1,RIT1,HADHA,ATAD1,SKP1,UNC45A,G3BP2,MTX2,H1-5,PPP1CB,MYL6,PHB1,HP1BP3,RPLP1,XPO5,ATXN10,RPL7,SPTAN1,KIF3B,NOP58,ERLIN1,STOML2,DPY30,PRPF19,PSMD3,PRDX1,TRA2A,DDX23,RPL23,ARGLU1,PPAN,SRSF8,RPS24,TRIM37,G3BP1,RBBP7,MCM6,FAM200A,NUP153,GTPBP1,RWDD3,EIF4A3,CHCHD6,RPS20,RPL13A,MAGOHB,RPL22,TECR,NONO,TUFM,PPP1CC,ATP5F1A,SQSTM1,SMC4,RPL4,EIF5B,AATF,MYL12B,RPS14,ATG16L1,HSP90B1,JUP,LMNA,CDK1,MRPS34,MACROH2A2,RPLP0,H2AZ1,SRP14,CTDSPL2,PWP2,TOP1,SLC25A12,PKIA,PSMD7,LTBR,THRAP3,PRDX4,MDC1,RPS13,CNOT6L,RPL15,CASK,MSRB3,NUDT16,ILF2,FAM83B,SF3B4,SNRNP40,ATP5F1B,DES,MORC4,TMED5,CCDC85B,H1-10,FTSJ3,NSA2,XRCC5,SNRPA,STAU1,SSR3,HNRNPA0,GNB4,SAP18,RPL27A,RALYL,ZNF362,NCOA5,KLC2,SRSF1,CORO1C,LYAR,PNPLA8,UTP6,PPIB,HSPB1,NDUFB8,TOP2B,PABPC1,CCT8,RTCB,RUVBL2,VDAC1,HMGN4,KRAS,H1-6,POLDIP3,HNRNPDL,KIF2A,RPL18,LIG3,RPS3,RPL10L,MAT2A,RPF2,RPS17,KCNMA1,BANF1,TWNK,HNRNPH2,RBM22,MRPL40,MARS1,TOMM20,SPTBN1,ZNF326,H2BC11,RPA2,SPRYD4,TRIM36,UTP15,COX4I1,ITK,SYNCRIP,PLSCR3,RPS16,CDC5L,TMPO,DKC1,RBM17,CMSS1,SNRNP70,TMEM11,TMOD2,RPL10A,RPS2,ATP5PF,SLC25A11,RPL3,KPNA2,PIWIL2,MTCH2,H2AX,NEFL,IK,CHAMP1 |
| 3.650e-13 | -28.64 | DDX6 (DEAD-box helicase 6) | protein interactions | 1656 | 472 | 205 | 19454 | 5460 |
MOV10,TIMM8B,YTHDF2,SRP72,SAP30L,ILF2,SPATA6,RPL23A,CNOT7,LSM4,EIF3E,RPS13,CNOT6L,AAMDC,NONO,TUFM,USP14,CASC3,CTTN,METAP2,SMAP2,CCNF,RPS12,UBASH3B,TRIM24,RPS20,TRIM27,RPL13A,MAGOHB,NDN,RPL22,RPS14,RBMS2,PAK5,JUP,RPLP0,RPL26L1,DVL2,RPA3,INPPL1,RPL4,GTF2I,NDC80,EIF3D,HNRNPA1,WDR12,DICER1,RB1CC1,NAB2,PHB1,RPL8,RPLP2,RPLP1,PBDC1,TSG101,NUF2,PPIA,TXNRD1,PNMA5,E2F4,RAF1,RPL29,SKA3,GTPBP1,RPS11,TRIP4,RPS24,ZC3H7A,FAM76B,TRIM37,ETFA,ZBTB14,G3BP1,PPWD1,UBE2A,CUL3,YWHAZ,BRCA1,LSM14B,RPS5,EIF3K,RPL37A,AP2M1,ACTB,RPL35,EIF4A2,PRRC2A,RPL19,TIMM13,EMC9,MCRIP2,YTHDF1,G3BP2,PYGB,ZNF24,EDC3,COPS5,PPIL4,SNRNP70,RPL24,RPL10A,RPS2,RPL32,SYNCRIP,RPS27L,FZR1,CAND1,RPS16,ARL6IP5,CDC5L,RPSA,DISC1,IK,DDX42,NUPR1,TAF2,SNIP1,DHX9,ABCE1,RPL3,PSMA5,RPL17,MEPCE,RPL7A,MAT2A,CEP70,GPRASP3,EIF3G,SPOP,UBE2H,IGF2BP1,RPS3,PSPC1,EIF2S2,TRIM54,SRPK2,PPP1R10,IDE,AGO1,SSR1,RPA2,ACACA,HECTD1,SEPHS2,HEXIM1,RPL27,LSM12,STK38,BCL6,EIF4E,WWP2,CIAO3,RPL6,CNOT2,DDRGK1,XPO1,YWHAG,YWHAH,AGR2,YWHAB,FUBP3,EED,NXT1,FAM98A,TOP3B,RPS7,TRAF2,RPL18,RPS23,CRKL,PABPC1,LSM14A,RPL31,PICK1,DCP2,HNRNPDL,RPS4X,HNRNPAB,SFN,MYC,BTF3,RPL39,H1-10,PNRC1,H1-1,RPS26,STAT1,DES,ESR2,RPL10,SHMT1,RPL27A,CNDP2,NUFIP2,CNKSR3,RPS28,JAKMIP1,RCCD1,YAF2,EP300,AKAP1,STAU1,FXR2,HNRNPA0,UFL1 |
| 3.991e-13 | -28.55 | CYB5R3 (cytochrome b5 reductase 3) | protein interactions | 1727 | 325 | 152 | 19454 | 5460 |
TMEM147,MRPS11,ERP29,COA4,NDUFA4,TMT1A,RNF26,SAR1B,SACM1L,TOMM6,TSPAN11,VDAC1,TNF,TMEM60,RPS7,MFSD6,CYB5R1,ISG15,E2F4,RAF1,TMEM14B,OTULIN,CYB5B,ITGB5,FAM136A,PDHA1,CHMP4C,RPN1,EZH2,CYB5A,OCIAD2,PHB1,WIF1,STOML2,SLC38A7,RAB5C,BPNT2,HADHA,AKAP1,HSPA8,RABAC1,COX17,ATP5MK,PEBP1,GNB4,PHB2,HSCB,EMC1,VAMP1,RAB6A,PRDX3,YIPF5,BET1,AGTRAP,ACTL6A,TOMM22,SLC25A3,FAM3C,ATP5PO,TMEM115,BST2,SEC61B,CYB5R3,VDAC2,GNB1,SPCS1,ACTB,REEP4,TENT5C,ATP5F1B,TOMM40,AK3,RAB11A,CYB561D2,COX6B1,ZMPSTE24,VMP1,FAXDC2,ICAM1,CYP1A1,SPCS3,GNG5,UNC50,SFXN1,NSDHL,RAB1A,FAF1,GALNT2,NSG1,NRM,UBIAD1,YIPF4,CENPM,PREB,ATP5PB,SLC25A20,NDUFS3,TMEM31,RAC2,HSD17B11,COQ8A,CD274,CAV1,AIG1,FUNDC2,CNIH1,PRNP,RPL35A,ARL6IP5,TMED9,ATP5MG,ADIPOR2,MOV10,ZDHHC15,SPP1,POR,NXPE3,DERL1,RTN4,MME,RPA3,HSPA5,TOMM20,TSPAN5,NINJ1,CDK7,UQCRC1,SNRNP27,SEC22B,SCLT1,GRM2,STOM,RPA2,PTEN,ELOVL4,ENO1,PLP1,UQCRC2,CDIPT,VIRMA,GNAI2,TXNDC12,RALA,NDN,MGST3,CSGALNACT2,ATP5F1A,VAMP5,RAB2A,REEP6,UBE2H,TRIM23 |
| 4.188e-13 | -28.50 | MTCH2 (mitochondrial carrier 2) | protein interactions | 23788 | 405 | 181 | 19454 | 5460 |
SMU1,VDAC2,LMBR1L,ESR2,ATP5F1B,PCCB,SERPINH1,CKB,LAMTOR1,AKAP1,RAB5A,DDX5,HSPA8,DDX39B,PHB2,UFL1,NDUFS2,TOMM22,PIH1D1,PPT1,CORO1C,NRSN1,PSME2,FAM219B,HSP90AB1,ADCK1,DDRGK1,RPL6,TSPAN10,NDUFB8,HSPB1,FKBP4,AGR2,RUVBL2,EWSR1,SDHC,NDUFB5,RPL31,VDAC1,USP30,KRAS,NUDCD3,STBD1,MIEF1,NDUFA12,PDHA1,NUDT19,PTPMT1,UQCRC2,ST13,C9orf72,ATP1A1,RIC3,CISD1,ATP1B3,PML,RAB29,TEX264,HSPA5,BNIP3L,HCST,CYC1,SAMM50,RPA2,COX4I1,SDHB,LMAN1,FUNDC2,CAND1,COX5A,FKBP8,RAB3B,INSIG2,SNAP29,ATP5PB,KBTBD4,NEFL,GPD2,SARM1,RMDN3,CHCHD3,TUBB,ACTB,HSD17B3,TOMM40,YWHAZ,HADHA,TTC1,EXD2,HSDL1,FBXL4,NSFL1C,HSCB,DUSP22,MTX2,SLC25A3,NDUFA5,TBC1D17,ARMCX3,VAPB,ATP5PO,ATP6V1A,CYB5A,ARHGAP25,PHB1,DNM2,WDR6,WIF1,NDUFS8,EGLN3,RPL7,PTPN5,BCL2L1,HAX1,BAG2,OPA3,HNRNPA2B1,NDUFA4,ARGLU1,HSPD1,ETFA,FAF2,GFPT1,CYB5R1,E2F4,RAF1,B3GNT2,CYB5B,RPN1,CCNF,OPTN,STUB1,VIRMA,GNAI2,SH3BGRL,UBB,UQCRQ,USP14,ATP5F1A,NDUFB10,NDUFC2,MAVS,SYVN1,RPA3,INPPL1,FBXW7,YKT6,SLC7A1,PDHB,UQCRC1,UBA52,ARHGAP1,TIMMDC1,PDCL,STOM,COX6C,CDCA3,EHBP1,PTPN1,SLC25A12,ZBTB2,ATP5PD,TOMM70,ATP1B1,SLC25A46,ATP5MG,MOV10,DNAJC7,UPK1A,ESYT1,EMC2,SEPTIN7,RAB1A,RIGI,DUSP21,GPAM,MAP1LC3B,CLEC2B,NDUFA2,VAC14,NDUFS3 |
| 4.293e-13 | -28.48 | CPSF6 (cleavage and polyadenylation specific factor 6) | protein interactions | 11052 | 504 | 216 | 19454 | 5460 |
PSMB7,USP39,ATP5PO,FEM1A,MFAP1,BRCA1,PFDN2,RIT1,CUL3,PRPF31,MIRLET7D,TNPO3,SNRPB2,ERH,CPSF1,SNRPD2,SNRPD1,EZH2,CHMP4C,POLR2C,MTMR2,POLR2D,RAF1,GIN1,B3GNT2,DHX16,G3BP1,TRIM37,PPWD1,SCYL2,TRIP4,PLSCR1,HNRNPA2B1,BCKDK,SRSF7,DDX23,HNRNPD,PRPF19,VPS26A,HNRNPA1,TRA2A,KCTD10,SRSF10,NUP35,FOLR1,PHB1,LMNA,P3H1,TOX4,LSM2,METTL14,WTAP,CPSF4,TXNL4A,MYL12B,NF2,RPA3,MME,PRPF4,PPIH,CDC73,PPIG,ZMYND19,RUNX1,PPP1CC,NONO,AR,MAGOHB,YES1,VIRMA,CCNF,CTTN,EIF4A3,CAMK1,MIR17,ILF2,TBK1,DDX39A,LSM4,THRAP3,SMN1,MDC1,PQBP1,HAPSTR1,ZC3H11A,HSD17B10,CLP1,MIR34A,ERCC3,THOC1,TOP1,POLR2I,AKAP17A,NCBP2,CWC15,MRPS23,G6PD,SSU72,MIR25,NUFIP2,NCOA5,CSNK1A1,SYK,ZC3H14,NEK7,UFL1,FXR2,HNRNPA0,TRA2B,STAU1,SAP18,DDX39B,HSPA8,P4HA2,EP300,DDX5,CHTOP,THOC6,ARMC7,MYC,CREBBP,PAPOLA,HNRNPC,BAG3,SNRPB,CPSF2,FBXO22,SNRNP40,POLR2B,ESR2,APEX1,CMTR1,MIRLET7B,CAAP1,SMARCB1,KLHL12,MAX,SUPT5H,CSTF2T,HNRNPF,KRAS,MIR155,CCAR1,CBLL1,HNRNPDL,PABPC1,RPAP3,EWSR1,FAM168A,AGR2,CRTAP,MAGOH,YWHAB,DDX50,WWP2,ZCCHC10,XPO1,DDRGK1,RPS10,HNRNPL,DYNC1I2,SNRPD3,SRSF1,FUBP3,WDR82,EED,RPA2,RPRD1B,WWP1,ZNF326,PPP1R8,RBM22,MIR29A,MIR10B,BAP1,RC3H2,LSM6,IGF2BP1,OAT,UBE2H,ST13,CSTF3,PPP1R10,SMURF1,SRPK2,PSPC1,PSMC5,DDX42,WBP11,CDC40,PSMA5,NUP107,TOLLIP,HNRNPK,MEPCE,PSMB10,MIRLET7C,PALM2AKAP2,TCEA2,DHX9,SNRNP70,MAP4,PPIL4,CD81,CSNK2A1,API5,GAPDH,CAND1,FZR1,NKAP,RBM42,CDC5L,MRPS9,SYNCRIP,UBE2N,ALYREF |
| 4.397e-13 | -28.45 | FBXO6 (F-box protein 6) | protein interactions | 26270 | 714 | 288 | 19454 | 5460 |
ERLIN2,FAF2,NEU1,EMC10,B3GNT2,HSDL2,PLD3,ITGB5,NME1,CTSA,RPN1,PCNA,HNRNPA2B1,SLC25A5,SCYL2,CHST10,HSPD1,RFC3,SIAE,COPS4,SEMA4C,EMC8,LAMB2,MYORG,HNRNPA1,STOML2,PSMD3,CLPX,RPL23,SLC25A21,VPS4A,AHSA1,PPM1B,RHOG,KRT8,COPS2,RPLP2,ATP6V1A,PHB1,DNM2,RPL8,OS9,DHX15,ERLIN1,AGK,COPS7B,TOR1AIP2,FAM234A,TMEM231,ACTL6A,WDR77,SLC25A3,FKBP10,HEXB,CRYAB,PSMA3,SKP1,CMAS,PSMC1,NPTN,GGH,MCM3,RFC5,ILK,RPS5,NTRK3,HSP90AA1,YWHAZ,MYO6,LMNB1,RPS9,PIGK,ARF1,B4GAT1,MAD2L1,B4GALT3,LGALS3,RBBP4,TUBB,NRM,CLEC2B,DDX39A,EEF1A1,CCT5,YTHDF2,TMEM126A,POMT2,ILF2,ALPL,HSPA13,EMC2,LIPA,IGF1R,TMX3,AGA,SLC25A10,EIF3E,FASTKD5,ARF4,TUSC3,TTC4,FARSA,HUWE1,ERLEC1,LAMP3,MIR671,PSMD7,LDLR,HSD17B11,OLFM2,AIFM1,SLC25A12,JMJD8,UBA52,LEPR,RARS1,MET,STOM,HSP90B1,P3H1,TIMM23,CDK1,LMNA,SPCS2,SMC4,RPL4,PDHB,GTF2I,GMPS,PPP1CC,TUFM,ATP5F1A,CNTNAP1,STK38L,CTSD,GGCX,XPOT,IVNS1ABP,SDF2L1,ACAT1,ALB,RPS20,GANAB,EIF4A3,TUBA1B,ENO1,UBB,TECR,B3GALNT1,LDHA,RPS7,TUBA1A,NCSTN,H1-3,HEXA,RPL18,UCK2,SEC11A,FAM168A,PDIA6,TRIM21,RUVBL2,PABPC1,CCT8,FSTL1,HNRNPDL,PRPS1,RPL28,RPS4X,RUVBL1,PSMA1,HNRNPF,QPCTL,YWHAG,PPIB,RPL6,PROS1,LAMP2,TGFB2,CRTAP,ADGRG1,SRSF1,CCT7,HSP90AB1,TOR1B,AASDHPPT,TCP1,HNRNPL,RPS10,NOB1,COCH,EDEM3,FDFT1,EIF4B,PPT1,MMP14,DDX5,HSPA8,SF3B1,ITGAV,GNB4,EEF1G,NDUFS2,EMC1,PRCP,TIMP1,PSMA4,HNRNPC,COPS7A,SERPINH1,ICAM1,SPCS3,PLA2G15,CCT2,PRMT5,EFHD2,VDAC2,POLR2B,ATP5F1B,PSMD4,MTCH2,RRM1,PSMC3,SLC25A24,TFRC,DHX9,ERO1A,RAB27A,ABCE1,SLC25A11,PCYOX1L,CTSC,CAPZA1,SRPRB,HNRNPK,CSE1L,L1CAM,NEDD8,GAPDH,COPS5,EDEM1,KARS1,SMCHD1,TUBG1,RAC2,NUDT9,ALYREF,COMT,RPL32,ITGA6,SYNCRIP,EEF1B2,STT3A,TMPO,SPTBN1,CHST7,CHPF2,CYC1,MIR7-1,ACACA,EIF2B3,SSR1,HNRNPH2,LRP10,IRF3,APMAP,CLU,HSPA5,MARS1,STK38,CHPF,RPL7A,RNASET2,SLC25A1,RPF2,MAT2A,CALU,OAT,ATP1A1,SERPINB1,IGF2BP1,DNAJC10,PTPMT1,PSMC5,UQCRC2,RPS3,ACP2,CTSB |
| 4.550e-13 | -28.42 | response to virus | biological process | GO:0009615 | 383 | 179 | 18204 | 5365 |
UBE2W,ACTA2,CLPB,MIR675,CALR,HYAL2,NCK1,TRIM8,IRF2,ZMYND11,VAMP8,TTC4,IFNA13,UAP1,ISG15,DDIT4,TANK,HCFC2,ISG20,BCL2L1,IRF7,TLR7,JAK2,NLRP6,STAT1,BST2,DHX15,MAP3K14,OAS1,TRIM22,CREBZF,EXOSC4,EIF2AK2,STAT2,BECN1,MIR130A,UBE2N,BANF1,CXCL9,CCL5,G3BP1,POLR3B,RNASEL,FGR,RNASE6,TLR3,MX2,DDX1,IL12B,BAX,RTP4,RSAD2,IL6,GTF2F1,IFNA10,IFNAR1,APOBEC3G,HSPB1,TRIM34,APOBEC3D,FOXP3,IL12A,ENO1,MX1,LILRB1,ELMOD2,SAP30BP,MOV10,HSP90AA1,IRF3,IFNGR1,AKAP1,CFL1,TRIM11,IFI27,IFNB1,RIGI,MAVS,NMI,POLR3F,PMAIP1,PIM2,ODC1,TPT1,POLR3H,IFIH1,IFNK,TLR9,ATG7,IRF9,MYD88,EXOC1,JAK1,DHX16,APOBEC3F,RNASE1,TRIM26,MIR21,IFNA2,NLRP9,DNAJC3,EEF1G,MIR146A,LGALS8,IFIT2,ATG16L1,TNF,SMAD3,XCL1,GPAM,NMBR,TRIM32,PDE12,NPC2,PSMA2,TRIM6,PHB1,CLU,MBL2,NLRP1,CXCL12,CD40,CXCR4,ITGB8,APOBEC3C,PYCARD,TRIM5,CXCL10,LSM14A,PML,APOBEC3B,KCNJ8,NFKB1,CGAS,APOBEC3A,CD2AP,NLRP3,TRAF6,TLR2,CCL19,TBK1,PLSCR1,ARF1,SERINC3,IFNG,IL21,AZI2,PRKRA,EXT1,MIR26B,NT5C3A,TRIM35,PHB2,ZNF175,CCL11,TOMM70,CCL8,CDK6,TRIM21,TRIM27,IFI6,SEC11A,TICAM1,IKBKB,TRIM15,CNOT7,IVNS1ABP,IL23A,BNIP3L,SAMHD1,TRIM52,IRF1,PQBP1,IFI16,OPRK1,NDUFAF4,TLR8,CCT5,APOBEC3H |
| 4.670e-13 | -28.39 | positive regulation of cellular process | biological process | GO:0048522 | 5719 | 1891 | 18204 | 5365 |
ROCK1,LYPD6,P2RY12,SUPT4H1,SYT2,MIR15A,CACNB2,IL17F,TAF10,CD47,PIK3CA,F7,ZC4H2,ICAM1,APEX1,TCIM,NLGN1,NTF4,CD58,BACE1,TFEB,MIR140,PDE4B,STX18,MIR939,THY1,RNF41,CD40LG,LAMTOR3,SERPINI1,RB1CC1,CSH1,OLFM2,MTA2,IL23A,VRK1,CD248,VEGFA,TIMP1,PRELID1,NUDT16,MTPN,EIF3E,FGF23,PPM1B,RRM1,SOX14,DEK,STMN2,NDUFAF4,FZD4,CAPN2,CAMK1,RXFP2,SLC6A6,KLF1,PIK3R2,CTNNBL1,AMIGO1,OSM,CCL1,TRIM32,TRMT112,GPAM,UBE2L3,MAGEA4,MED9,CYB5D2,TMOD3,MED23,LAMP3,SERTAD1,CNOT6L,APBB3,VSIR,MIR101-1,PRDX6,FBXW7,PRR5L,EAF2,TESC,NOG,S100A8,ZDHHC17,APOBEC3C,TRIM5,SELENOT,HILPDA,PITHD1,FGF16,SYK,NLRP1,PROM1,BOLL,SERTAD3,NPPC,NPSR1,IGF2BP1,DUSP6,PSMC5,CHCHD2,CLEC9A,CCL2,ARL2BP,JMJD8,POU1F1,PDE2A,TMEM97,DPP4,VAMP3,DIRAS1,PIAS1,CYRIB,TBK1,XRCC5,CDK4,FEZ1,APOBEC3A,G6PD,RARRES2,RAB5A,SLC12A2,CD1B,ZNF287,TP53INP1,EIF4E,HAPLN2,NDST1,ID4,PTP4A3,ASPM,MIEF1,PADI2,GADD45G,POLD4,ZNF513,LRRTM1,TMEM100,UBE2K,MMP14,HAX1,CLIP3,PAFAH1B2,E2F4,SMARCE1,TENT4A,KLHL25,PPP1R12A,ACTL6A,CA2,AKT3,FOXP3,CD274,MIR1224,OPTN,CDC42EP4,BABAM1,TP53INP2,NUS1,PRKAG1,CASP12,SMYD3,TPPP2,RIGI,PAX6,SAR1B,WNT10B,TXNIP,NACC2,SEMA4C,AQP11,EHD4,LCP2,SFN,SYT4,MIR96,TNIK,ZNF507,IFNK,ATG7,SMARCD3,HDAC3,ZNF24,ZBTB16,OCIAD2,SH2D1A,RAB3D,BAK1,VDR,MAP1B,TCAF2,CXCL11,TEF,OXTR,CIBAR1,NFKBIA,LPAR6,BRD9,SPRED1,SNX18,TCF23,ASPA,SIRT7,NCR3,DUSP26,RPS4X,TMED4,FUBP3,RPL26,CCT7,SERTAD2,GPC1,ITGA2,CEBPE,VSTM2A,WNT7A,AIFM1,TGFB3,PRKCE,GLCE,RGMA,MIR10B,ATF1,LCP1,PPP3R2,TAF11,B4GALT1,FGF1,MIR125A,NRP1,PCSK9,CCL28,CCND1,PAK2,CYTL1,MIR130A,IL2,MIRLET7B,SOD1,AR,CNR1,XBP1,PID1,HPCA,KIF3B,MIR1-1,NCBP2,DDX5,SSR1,SDCBP,MDM2,FADS2,MIR188,TP53,ARHGEF39,ST3GAL4,CRBN,PAX9,JADE1,DLG4,TMEM33,ACKR3,ZNF473,PTPN1,BAG2,CSRNP3,HSPA8,MIR195,FAF1,MIR198,DROSHA,HEXB,LGALS3,KPNA2,CYP27B1,GPM6A,TRIM15,CXCL13,UFL1,RBM3,CD247,S100A6,MLC1,TRA2A,CDKN1B,TRIM52,FOXJ3,TESPA1,FCGR2A,MID1IP1,PHB1,ING1,CX3CL1,NGRN,PPT1,MUL1,MIR98,CCT8,GTF2A2,DUSP10,FGF7,STUB1,RANGRF,CXCL12,PLAC8,CLDN4,GOLPH3L,CDK5,KCNMA1,PNMA2,CASP4,CCL18,ILK,RNF152,TAFAZZIN,ZNF365,GPR89A,MIR301A,NPY5R,NLRP2,SUPT5H,TENT5C,LSM14A,MED4,CDKN1A,CLDN3,ARF6,IRF4,PDCD1LG2,CSNK2B,TENM3,ZHX3,ZBED4,MIR214,CCL25,NLRP3,TPPP3,CCL17,FLCN,FZR1,NUPR1,AGO1,SOCS2,DUSP19,RORB,CCL5,KCNB1,FCHSD2,TLR3,TRIM68,CDC16,AKAP12,DYRK2,MAP3K12,HEY2,IRF3,SETD7,OPRM1,STK3,PARD6A,KLF12,RAB9A,MIF,HNF1B,MIR132,BCL10,IL12A,RWDD3,EIF5A2,SWAP70,TADA1,GPR35,MIR150,LANCL2,AP2M1,EFNA5,ING2,RUVBL2,GPBP1L1,CSNK1G3,FXN,CBLN2,FAM98A,MIR146A,DGCR8,NKRF,MDC1,TACR1,IL4,ILF2,GADD45B,SESN3,ADD1,RERE,RPRD1B,SCAND1,CD209,PARM1,MAP2K3,DUSP3,LRP3,SEMA5A,RNF8,STAT6,CCR7,HAND2,PRDM4,CFAP20,MBD3,C9orf72,ADRB2,RFC2,GAS8,VAMP8,DKK1,HOXB1,PKP4,DRG1,CCR1,IRF8,REG1A,NUCKS1,FKBP1A,CDC5L,NR1I2,DHX15,ANAPC11,PRPF19,DNPH1,PELO,ING5,SNAI2,EFNB1,LTBR,CYP1A1,BRINP3,MVD,DLG3,RAB3A,RBM23,HOXC4,PAEP,AZIN1,GHRL,CSNK2A1,HNRNPA0,PROK1,BAG3,RHEB,SOX9,NDFIP1,CBL,PDCL,OAZ3,PRKRA,MEF2A,MIR135B,TACR3,LGR4,TOM1,BIRC5,DTL,GPR37,PGRMC1,TAB2,IFNG,HEXIM1,CD1A,TRIM21,ATF4,HNRNPK,PTGES3,PNMA1,NRDE2,MTMR2,SRC,ADRA1A,PPID,ZNF609,ANGPT1,BMPR2,ADGRG1,MIR29A,BNIP3L,EXOSC3,SMAD9,TICAM1,AKR1C1,UBL5,NDC80,MECP2,IFI16,FLRT2,STARD4,NTRK2,LMO3,CCT5,CTNNBIP1,SHOC2,BLOC1S5,NBN,ACTR2,METTL14,PQBP1,IRF1,UTP15,AFAP1L2,WNT2,HNRNPD,CCN3,KLRC2,TAF9,KMT5B,TMEM108,EIF4A3,TRIM62,SELENOK,IFIT2,ATG16L1,MIR24-1,ISCU,SMAD3,CSRNP1,DUSP22,CD63,ATF3,FCGR2B,ELP3,GFUS,STAP1,MIR205,RALB,KLF10,TESK1,DYNLT3,ARG2,NFKB1,PLP1,SUPT3H,CCL4L1,IGSF11,P3H1,LIPT2,HLF,IRF2BPL,FOS,CHI3L1,SYBU,FAM168A,LRTM2,CCL19,LRRN1,TRIB1,SYCE3,PLAGL1,TMEM59,RNF40,MIR181D,AGGF1,TRAF6,NLGN2,CCDC25,TICAM2,MIR222,USP2,RSAD2,BGLAP,MIR107,CFL2,ZFP64,UBB,CXCL9,FOXP1,PEA15,STOML2,MIR185,DUOXA2,POLR3B,UBE2E2,IL12B,DPP10,RNF14,UBE3A,MTA3,TMEM196,MIR449A,FLOT1,CXXC1,SLC1A3,GPR37L1,RNF122,PNP,JUN,MORC2,HSPD1,TAS2R13,VDAC1,SNAPIN,MIR210,POLR3F,MIR33B,RMND1,POU5F1,ELK1,CHMP2A,LYAR,SIN3A,VAV2,RRAGB,MIR375,LILRA2,MSX2,MIR30B,INHA,MIR519D,VWF,RTN4,MIR548C,ILDR1,MYBL2,RGCC,TIA1,NPR2,BACH1,SLC1A2,CTSK,CCL24,TMEM106A,GPX1,PNMA5,EP300,RFC3,PIK3R3,WDR77,OVOL1,BOK,PRMT5,DRD3,GRB10,TANK,LMNA,FAM53B,CDC7,UBE2V2,MIOS,RAMP3,KPNA6,GSK3A,MIR545,G0S2,BAD,BCL2L1,ATP8A1,P2RY10,STXBP1,LIMS2,BST2,PKIB,TIRAP,ARRDC3,CDK12,PLAA,DIRAS2,TRIM24,RIC3,MSN,CRKL,AATF,ADRB3,ODAM,HTRA1,MIR206,MLLT11,KCTD20,VPS72,MITF,CLEC7A,IL21,VPS4A,MIR34A,IL13,TAF7,DIPK2A,IDO1,CD1E,TENT5D,MADCAM1,SPPL3,ENC1,NETO1,CCL11,MICB,HUWE1,PTPN11,CDK6,TFPT,GHITM,LRRC8A,TRIM27,ATXN1L,FGFR1,HELT,SGIP1,ACSS2,VGLL2,SCAMP5,ESR2,CAPG,ITK,IL7,RFXAP,EZH1,OSBPL8,IER2,CHRNB2,RAD21,SLC6A4,TPBG,GAPDH,TGFB1I1,MYRF,CNOT7,JAML,LIPA,RACGAP1,SP1,CSNK1A1,CCNA2,PTGER4,SFRP4,RPL23,RAP2A,RNF20,TSPO,PDE9A,STK24,RELL2,JUP,GPNMB,MIR711,RNF187,RHOJ,AAMP,NMBR,MRGPRX2,TRAF2,H1-1,EEF2,RPS3,TMEM106B,TRIM6,CCR3,ADIPOQ,LBH,FGF17,YAF2,H2AZ1,ROCK2,LARP4B,S100A10,CAB39,AGER,ZNF304,MIR23A,RHOB,BATF,PLEKHF1,TAPT1,MIR495,CORO1C,YTHDF1,CXXC5,MME,INO80C,ZNF770,EPHA2,STX1A,H2AX,RAG1,FBXW11,LGI1,MIR424,TRIM23,OGG1,ICOS,PSMD10,TNFRSF14,CXCL10,ATAD1,SPHK2,CIDEB,ZNF622,HSPB8,MIR657,RHOH,CFTR,TFDP2,DDR1,LDB1,FRMD8,CREB1,GPR17,IFNAR1,PRDX3,PTGES,SPON1,G3BP1,WWP2,HNRNPA1,DOK6,SMAD5,USP15,SYNDIG1,TGIF2,HSP90AA1,CDK5R1,WDR45,SNAP25,SASH3,PSRC1,CD83,HTR2A,INPP5K,APLN,MARCHF5,FKBP1B,HSP90AB1,CBFB,CD28,PTPRZ1,KCTD17,MEF2C,TNFAIP8,MSTN,CAV3,ACHE,SLC20A1,ARPC2,HTR1A,GPBAR1,USP8,RC3H2,ZGLP1,S100A11,HBEGF,PLPP6,AP2A1,TRIM26,EGR2,ARL6IP5,LILRB4,RPS27L,IFIH1,MIR208A,RUNX1,ZMPSTE24,GFI1,CRB3,SNX3,TAF2,MIR421,GKAP1,ATP5F1B,PCNA,ZBTB38,SPRED2,NOTCH2,SVIP,SRPK2,RASL11A,RIMS4,ACTA2,SMC4,CHP1,TGFB2,CRYBA1,FCN2,MIR144,VPS4B,SNX33,TPPP,CDH13,FOLR2,PIWIL2,MTDH,ENHO,ADTRP,GREM1,TRIM37,IRF2,RAP2B,USP13,PTPN22,SOX2,NFKBIB,PDE8A,ABHD14B,PXYLP1,PAGR1,CTBP1,PRKCB,SHC1,CHGA,RAP1B,TRAF3IP3,PFDN2,ATP2B4,NCKAP1,EDEM1,MAD2L1,MMD,MACROH2A1,RIT2,TMOD2,IFI35,ATP1B1,CDK7,MAFG,CCL21,MIR20A,TADA3,NFE2,CIRBP,CTNNA1,FZD3,TNR,BAZ1B,CACUL1,PDCD4,NEO1,SURF4,STAU1,CAMP,ETV6,MIR143,PAFAH1B1,NLE1,TIAM1,CDC23,SCHIP1,HNRNPA2B1,NECTIN2,PIK3CG,REG1B,FASLG,NEGR1,IL18,ELK3,WRAP53,TAS1R2,UQCC2,TRIM35,SLC38A2,LAMTOR2,NF2,CCAR1,PRRT1,TLR1,RPS12,MIR137,MIR769,IL15,FABP5,BCL9,TCP1,OPRK1,ELK4,NIBAN2,STIM1,ADIG,CCNB1,STOM,TRUB1,ZNRF1,NR2E1,PIK3R1,RAN,SETD4,CUL3,PDCD1,VMP1,PRKAB1,EGFL7,YES1,SLC23A2,BIRC2,STAR,LACRT,CD2,NIF3L1,SPTBN1,TCEA1,WEE2,ATRAID,PARP2,POLDIP2,FOXA3,NME2,RGL2,SGF29,HDAC6,TMED9,STK11,CREB3,ALKBH4,MED22,CCAR2,NR1I3,SAV1,MED10,DERL2,ACVR1B,CD40,DCUN1D3,CACNB4,RDH10,CHRM3,MIR16-1,PIH1D1,DRD1,MAP2K6,IL2RA,NHERF1,MAPKAPK5,NUP62,WBP2,PTHLH,PICK1,AKAP8L,EEIG1,RNF10,VIP,STAT5A,CDC42EP3,MRPL12,TLR2,MIR183,CYP1B1,GP9,BAX,TRAF3IP2,EFCAB7,MOB3B,IL6,AGPAT1,TOM1L1,MMP9,CD86,IFNA10,PAIP1,SOX21,DNAJC27,MIR223,G3BP2,ACVR1C,ACSL4,ELF1,SLC7A1,FCER1G,DDX1,OXSR1,PRNP,SF3B4,IQSEC1,EMC10,GPR137,SLX1A,GNG5,DAPK3,OR2AT4,AKT2,PLXNC1,UHMK1,FAM89B,DHPS,FUT1,GABPB1,UCN,LPAR2,CD80,MED27,MNS1,NCAPG2,GTF2A1,GPR65,MAD2L2,SSBP3,MIR204,CLEC6A,DSTYK,EDNRA,NMI,SELENON,IFNA2,CDC73,MEF2B,DNAJC3,PPP1R10,PLCB1,TLR9,TNFRSF1B,MLLT6,ADM2,PPP2R5A,MCL1,GH1,TNFAIP3,RBBP4,TXN,GID8,GSTP1,MAX,MT3,CREB3L4,NEUROD6,TOX,CCND3,RETN,IGF1,HMX2,ROMO1,PTRH2,DKC1,ENY2,CNOT2,MIR675,ABCB1,CALR,SLCO3A1,IFNA13,TLR6,AGR2,PFKFB2,RANBP1,SLC45A3,ELAVL4,MIR182,PPP3CA,FAM107A,AKT1,DYRK1B,IL1B,CDK5RAP3,ACER3,MIR448,ROGDI,E4F1,TFG,PPP5C,TSG101,NR1H2,PLA2G5,TGFBR2,KLRD1,RND2,HNRNPAB,TSPAN5,MIR320A,MET,FAS,KIT,ANP32B,FLRT3,TNFAIP6,SOST,MAP3K3,AVPI1,LEPR,SOD2,NEK7,OAZ1,EHD1,BRINP1,ACTL6B,SDC4,TNFSF10,STK4,GNAI3,CIAO1,ST6GAL1,KLF4,ZBED3,HOMER1,PIP4P1,ARF4,APLNR,TLR4,RPS15,GABBR1,ITGAV,CNOT8,MIR99B,MGMT,TRIP4,CRABP2,ZNF574,SAP18,MIR26B,LAMB2,LARGE1,BRINP2,GHR,RAP2C,B2M,LHX2,ATAT1,PRIM2,GTF2I,ZNF668,S100B,LUM,HMCES,C1QTNF1,HINT1,RBCK1,APOC2,SIAH1,TRIM44,MIR503,MIR212,DSTN,SGTA,EPCAM,F10,PLGRKT,NQO1,KLHL22,IMPACT,MAPRE1,PPP2R1A,TNFAIP8L3,IRAK4,SUFU,RHOG,SEC13,SLC25A4,AVPR1B,RUVBL1,PDIA3,LRRTM2,SLAIN2,EDA2R,TWSG1,FGF3,ACTB,HMGA1,TNF,XCL1,SF3B1,RBPJ,EMILIN1,MED11,TBC1D24,ITGB8,HINFP,ABHD5,OAZ2,LURAP1,PLG,MZB1,IL1RAP,ORMDL3,TOP2B,RHOU,BCL6,SH3BGRL,HFE,CTDSPL2,NSFL1C,RAB31,LRRC4B,CITED1,RB1,SLC25A5,NFYA,TMSB4X,CDK9,RBM5,NDN,ALDH1A3,AIF1,SLC25A27,FOXC2,TIFA,CTSD,NEUROG2,MIEN1,GJA1,CHST2,MIR17,CNTN1,CEBPG,FERMT2,IFT172,CSNK1E,RTRAF,IGF1R,SFRP1,PPIA,CDC42,LRRTM3,ZDHHC15,KCNC1,MIR200A,EPHA4,MOSPD1,IL2RB,DEFB124,PELP1,BTN2A2,CSF2,RFX4,IL6ST,GTF2F2,BARX2,MAB21L1,FRZB,YWHAH,RASL10B,ATP5F1A,CCL3,TEDC2,SCG2,TPD52L1,CNTFR,LILRB1,RPS9,MAD2L1BP,MYORG,SEPTIN7,STAMBPL1,CDKN2AIP,DOK4,EEF1E1,TYROBP,CLIC2,ZBTB17,DEPDC1B,MAVS,FURIN,TMEM101,KANSL3,LSM10,CD46,MIR149,IGFBP3,NLRP9,ATP2C1,ARPP19,CD81,BEND6,HTRA2,IL20RB,SOCS5,HSPA5,MYD88,NPTN,TAF5L,DEFB1,LTB,RAB29,TLE1,KCNMB1,TRIM8,MIR346,OSBP,UAP1,CCR6,ISG15,RNF167,HCFC2,ZNF345,CA8,MSL2,COL3A1,DHX9,SPP1,FAM20C,BTBD10,MAP2K1,HDAC5,MIR511,PPP1CC,HGS,PRMT2,KCNIP2,FCGR1A,IGFBP4,ANKRD49,OR51E2,RGMB,SLC38A9,EDF1,IL5,TLR7,ZBED1,MIR29C,KDM1A,TOPORS,BECN1,DICER1,FIS1,CBLN1,DNAJB9,SF3B5,CNOT6,DLG1,HCST,RGN,SUB1,EXOSC4,PDF,ANKRD6,STAT2,STK16,RAB8B,ARHGAP5,RNF146,DYNLL1,SERINC3,DOK5,MED17,CBLL1,PHB2,ZNF175,EPS8,CD200,WIF1,TM9SF4,POLR2G,SQSTM1,LEP,TNFSF12,KCNJ11,NME1,FAM162A,DAG1,STAC3,SH3BP4,CALY,SMARCA5,SLC38A1,SEMA7A,TFE3,MPV17L2,AKR1C2,COX17,FBXO7,SOX3,NFE2L2,BMPR1A,SLITRK1,SMARCB1,NTRK3,ZNF319,MIR296,TLR8,BORCS5,CCDC3,TOMM7,RFXANK,EIF2B5,TRIM3,BRMS1,GSTO1,TUSC2,SLITRK2,PIK3AP1,RAP1A,CLTRN,TFRC,PCBD1,ALKAL1,CRTC2,NKX3-1,PKNOX1,RPS7,ADIPOR1,CLU,MACROH2A2,TMEM164,CCL23,MED30,IL15RA,EIF2S1,FUT9,MIR141,TERT,CRADD,PABPC1,UBXN2B,FGF13,SRI,GNA11,BMPR1B,TASL,TFCP2,HCLS1,DISC1,PML,C2CD2L,GRM2,SFTPD,TLR5,CTLA4,NINJ1,NEK2,CD2AP,LAMTOR1,CD38,GSKIP,FXR2,MARCKSL1,GADD45A,NDP,ERP29,STAMBP,SLITRK5,GTF2F1,CSK,RFX5,BTG1,ZNF267,THRAP3,LDB2,RNASEL,FGR,MIR10A,GRM1,ZNF263,NEUROD2,ADRB1,PELI1,PPARA,RXRG,IFNGR1,VEGFC,TRAF7,MIR186,JUNB,OTX2,PRL,TRIM34,NCKIPSD,HAS3,LDLR,ENO1,TRPC1,DMAP1,BAP1,PMAIP1,RBBP9,CD36,FOXD3,IREB2,TCF21,MED29,TTC23,DHRS4,CPNE1,ELP6,ANAPC2,MIR21,FGFBP1,CACNG3,ECD,PCK2,MOB3C,NOS1AP,DNM2,EMP2,SMURF1,ELAPOR2,GPRASP3,SYNCRIP,GLIPR2,JAK1,UBE2B,CD99L2,CREBL2,CTNNB1,SLC1A1,MIR95,SHLD1,HYAL2,KLK5,GPT,CYFIP2,RALA,SNX5,CERS6,PDCD10,TTL,EIF3D,NAA16,PACSIN3,KARS1,SEMA3C,INO80E,SMAD4,UBE2V1,CALHM2,TNFSF15,NDNF,DVL2,LACC1,TEX261,L1CAM,CRY1,SLC4A8,CD34,SMCHD1,RAB27A,MED31,MORF4L1,PTEN,JAK2,LMO2,CAND1,VLDLR,STAT1,TTI2,STX7,IRAK1BP1,LRP6,SS18,UBE2M,MIR221,ATP5IF1,PSMC3,CARTPT,UBE2N,RRN3,TNFSF13,CREBZF,CDC42EP2,RIOK2,GRIA1,LMO4,EIF2AK2,CD14,GNAI2,RLN2,ITGA6,SCN1B,UBP1,ATG101,UBE2D3,CCNY,MIR133B,CXCL8,LPAR1,RRAGA,ERCC3,RRAS2,CTSC,FKBP8,TMEM30A,TOMM70,MIR590,CCL8,DNAJC2,EYA3,DDIT3,SRSF1,P2RY1,TSHR,NKAP,PRDX2,RAC2,FGF22,SIX5,ADORA1,AAMDC,YTHDF2,RPS20,NCSTN,NFYB,CHRNA7,ADCK1,EZH2,IL3,UPF3B,NR4A2,MIR28,MNAT1,EPO,EGR1,CHCHD4,IKBKB,IL34,CLSTN3,PPARG,CCDC22,MIR30A,SRARP,GAB1,F11R,PRKCQ,SESN2,MIR106A,FAXDC2,PGR,ZNHIT1,RFC5,NKX6-2,MSX1,CX3CR1,MIR145,VAMP7,RAB11A,LY96,DDRGK1,MAP3K11,CRLF3,POLDIP3,NAA15,RBBP7,CACNB3,ARMCX3,SLC39A10,RAF1,MIR640,IL10,PTGFR,TMEM198,CXCR4,TRIM46,GABPA,LRRC24,PYCARD,HRAS,CD226,CD1D,HMGB1,MAPRE2,BCL7B,KCTD11,DFFA,ABHD17A,ZDHHC8,MBL2,PNMA3,VPS28,KLK6,SSBP4,PTK7,RGS2,ASIC2,TRA2B,CGAS,VIPR1,ADNP,CTTN,STRADB,RELL1,VAMP2,ZNF593,SH3GLB1,RFC4,USP16,POMT2,PIP4K2C,EDEM2,CCR2,F2,PLSCR1,BCL7C,CAPN1,PRKCA,NEFL,BRD3,LMAN1,AZIN2,CD1C,ACVR1,TBC1D5,ATP1B3,MYC,MIR126,DAPK1,SEMA6C,CDC20,HSPB1,MIR142,MARS1,CASK,GPSM3,SOS2,RIMS3,HCRT,DLX1,SSBP2,MED21,NFIL3,TNFSF8,MTCH2,KCNJ2,PDCD5,DDT,SSBP1,ATP6AP2,CDK1,OSR2,RPS6KA4,PIM2,ODC1,CNPY4,BLOC1S3,AGAP2,NDUFA4,RAB1A,SUPT7L,MEPCE,MCOLN1,SOCS3,CAV1,IFNB1,TNKS,TAB1,MEAF6,APOBEC3F,UBE2I,SNRNP70,MIR324,FAM83B,CLDN1,CD4,PTN,PSEN1,TNKS2,RBM22,IRF9,SMAD2,MIR342,BRCA1,SLC38A3,MIR31,BUD31,FGF10,ADAMTS1,TF,IRF6,IL2RG,NCK1,KRAS,MBD5,DPY30,IL1A,KLK3,CCL20,PROX1,CREBBP,TNFSF18,ZBTB18,WASF3,WASL,GSTM2,DYRK1A,FOSL2,LTA,CLRN1,COPS5,SUMO1,CDCA7L,HNRNPC,RNF126,OAS1,TWIST2,SETD3,MIR200C,CCT2,SMAD1,CHRM1,IRF7,CD151,RER1,NLRP6,MIR1260B,RETREG3,ACTN4,CAV2,PYM1,LITAF,PICALM,SLC35F6,ADAMTS20,TRIM22,MTF1,FEN1,AIP |
| 4.748e-13 | -28.38 | USP36 (ubiquitin specific peptidase 36) | protein interactions | 57602 | 591 | 246 | 19454 | 5460 |
RPS23,RPL18,MTA2,TUBB4B,EEF2,RPS7,TRMT1L,UTP25,RPS4X,RPL28,RUVBL1,HNRNPF,MMP9,FBXO11,CCT8,ABCF1,RPL31,CTNNB1,UTP6,NGDN,MIR29C,RPL6,IFI16,DDX50,TCP1,SUMO2,LYAR,EIF2S1,ISG20L2,RPS10,CORO1C,EED,PPT1,EHHADH,RPL27A,STAU1,EEF1G,PSENEN,DDX5,HSPA8,XRCC5,DNAJB6,POLR1B,RCL1,NSA2,RPS26,FTSJ3,RBM27,S100A11,H1-10,CCT2,RPL39,MYC,ESR2,RPL10,APEX1,SNRNP40,PSMD4,RBM34,TMEM31,RPSA,MRPL47,SRFBP1,IMP3,RPL17,KPNA2,IMP4,H3C1,DHX9,MRPS18B,RPL3,SNIP1,RPL10A,AKAP8L,NOL12,RPS2,RPL24,CAMP,HP,CMSS1,SURF6,DKC1,SHPRH,IFRD2,RPS16,ARL4D,RPL32,ALYREF,SSBP1,MIR7-1,E2F6,MIR21,UTP15,TFB1M,RPA2,H2BC11,GTF3C4,MIR34B,MIR29A,WDR55,AIF1,RPS15,WDR3,LCP1,DLAT,EXOSC4,NLE1,RPL27,ALKBH5,RRP7A,EXOSC1,ATP1A1,ARHGAP21,RPS17,ANAPC15,RPL7A,MAT2A,RPF2,SMARCA5,SRPK2,RSL24D1,RPL10L,MACROH2A1,FGFBP1,PSMC5,ZNF330,RPS3,EXOSC3,EZH2,BPIFB1,RPN1,MAK16,RPL29,SSRP1,GTF3C3,RPS27A,TRIM26,G3BP1,BAG2,RPS24,COX8A,PCNA,PPAN,SCYL2,RPL23,RSBN1L,LYZ,DDX23,WDR12,NDC80,PSMD3,KIAA0232,RPL7,ATXN10,NOP58,HP1BP3,RPLP1,RPLP2,MRTO4,MYEF2,RPL8,WDR6,RPL9,RND2,CMAS,COIL,NOP53,RADX,CCDC86,HADHA,EMG1,UPF3B,DCAF4,LMNB1,MYO6,TAFAZZIN,NOP16,PRRC2A,RPL19,RBBP4,RPL7L1,RPF1,MRPL23,RPS9,RPL37A,SRP72,SOD2,JCHAIN,MIR17,LLPH,RPL15,FCF1,EXOSC8,MRPL11,H2AJ,RIGI,PTGES3,TF,NOC4L,PAK1IP1,RPL23A,NKRF,MPHOSPH10,GRSF1,TOP1,RPL35A,PWP2,KRR1,AIFM1,RPL12,H2AZ1,SRP14,MACROH2A2,RPLP0,NOL7,RARS1,ZCCHC17,MRPS34,UTP23,AATF,BRIX1,NHP2,FBXW7,RPL4,GTF2I,TTR,DGCR8,EIF5B,NPM3,MTDH,H2BC12,PRPF4,PNO1,PPM1G,RPA3,AP2A1,PPP1CC,ATP5F1A,RPL26,VIRMA,RPL22,RPL13A,UBE2I,ODR4,PELP1,MIR16-1 |
| 4.878e-13 | -28.35 | regulation of blood vessel endothelial cell migration | biological process | GO:0043535 | 158 | 90 | 18204 | 5365 |
ATP5F1A,VASH1,FGFR1,MIR885,ANGPT1,MIR132,AKT3,MIR10A,KLF4,VEGFC,MIR939,MIR188,MIR133B,MIR200A,MIR126,MAP3K3,MIR15A,HSPB1,MIR143,MIR135B,MIR193A,NR2E1,GAB1,MIR31,RHOJ,RGCC,MIR342,JUP,MIR212,MIR503,PPARG,MIR296,SP1,MIR149,MIR146A,MIR30A,FGFBP1,MIR137,NFE2L2,MECP2,MIR204,VEGFA,MIR129-1,MIR210,NUS1,MIR150,MEF2C,HMGB1,MIR205,MIR495,CD40,STARD13,EPHA2,AKT1,MIR152,FBXW7,MIR361,MIR23A,PLG,MIR505,SPRED1,TNF,PDCD10,MIR640,MIR101-1,MIR24-1,MAP2K3,ATP5F1B,PRCP,MIR320A,MIR20A,PRKCA,MIR206,GADD45A,FOXC2,MIRLET7B,MIR221,MIR492,STAT5A,MIR497,CSNK2B,MIR29C,MIR200C,ATP2B4,NRP1,TMSB4X,HDAC5,MIR16-1,MIR10B,MIR424 |
| 4.896e-13 | -28.35 | IMMT (inner membrane mitochondrial protein) | protein interactions | 10989 | 400 | 179 | 19454 | 5460 |
SMN1,MDC1,FASTKD5,PDE2A,DNAJC30,SFXN1,NDUFS3,EEF1A1,TAF1D,CCT5,SLC25A12,MSMO1,PLGRKT,ZBTB2,CDK9,CGAS,TRAK2,AIFM1,PTPN1,DNAJC4,ESYT1,SLC2A1,HDAC6,SLC25A46,CALR,PDHB,SQSTM1,SIRT7,RHOU,HSP90B1,GRM2,CDK7,FAXC,UQCRC1,ATG16L1,VIRMA,UQCRQ,RHOJ,MGST3,TRIM24,ALB,CHCHD6,CCNF,OPTN,DNAJC19,HMOX2,ATP5F1A,IMMP2L,RNF26,TRIM37,SLC2A8,NDUFA4,RNF126,PPID,EZH2,LGR4,B3GNT2,NUP35,NDUFS8,EGLN3,SDHAF2,HP1BP3,GATD3,HNRNPD,RHOG,MARCHF5,G3BP2,FBXL4,SLC15A1,HADHA,CRY1,EXD2,DUSP9,ARMCX3,KLF3,TIMM29,RND2,MTX2,MAD2L2,PARL,PRRC2A,CHCHD3,MTM1,CDC7,RMDN3,HTRA2,FAM107A,RHOB,PDE4B,TOMM40,ACO2,AUH,KDSR,FKBP8,MEPCE,KPNA2,LRRN4CL,ABCE1,CLPB,MAP1B,FURIN,NUPR1,ZFP1,DISC1,APOO,MGARP,MTCH2,KBTBD4,TMPO,RAC2,COX4I1,MAP4,TMEM70,CD81,TOMM20,SLC25A51,KDM1A,RNF113A,RAB9A,CYC1,HEXIM1,SAMM50,FGFR1,CFTR,GABRA1,NEK2,CDC42,PTPMT1,UQCRC2,UBE2H,DNAJC5,SLC25A1,PFDN1,VDAC1,KRAS,NDUFA12,PTRH2,PDHA1,DNAJC25,ISG15,NCSTN,SNAPIN,TOP3B,RMND1,COX14,RHOH,ADCK1,STX5,FEZ1,HSPB1,AGR2,CTNNB1,DDRGK1,RAB5C,ARMCX2,RER1,ADRB2,PHB2,NDUFS2,UFL1,MED13L,AKAP1,EP300,HSPA8,DDX39B,PIH1D1,PAK2,BET1,TOMM22,ESR2,LRIF1,ATP5F1B,DLST,CCDC90B,VDAC2,LMBR1L,FIS1,PLA2G15,MYC |
| 4.933e-13 | -28.34 | ESYT2 (extended synaptotagmin 2) | protein interactions | 57488 | 353 | 162 | 19454 | 5460 |
RHOG,YWHAB,RPL23,PEX3,HAX1,C2CD2L,RAB5C,LAMP2,DDRGK1,YWHAG,YWHAH,RHOH,OSBP,HNRNPL,DIRAS3,PHB1,WDR6,RAB35,STX5,KRT8,GJA1,RAB4A,RPN1,STIM1,MOB3C,EMC10,STBD1,ERLIN2,TUBA1A,NCSTN,DNAJC25,FAF2,SOX2,EMC8,KRAS,RETREG1,FLOT1,PAEP,TMT1A,COX8A,SCD5,RHOB,LAMTOR1,FAS,VMP1,SCFD1,RAB11A,CUL3,VEZT,TMEM38B,RIOK2,REEP4,ATP6AP2,CHP1,MAD2L2,LMBR1L,SEC61B,GPR89A,RMDN3,RRAS2,EMC9,VAPB,TOR1AIP2,FBXO42,BET1,PGRMC1,NOTCH2,USP6NL,SEC62,OTULINL,CNPY3,RND2,HSCB,EMC1,STX7,EP300,RAB5A,HSPA8,ESYT1,POR,AGPAT1,OSBPL8,NUS1,RPS2,SLC25A46,DHRS7,EMC4,TMEM199,DPP4,HM13,DERL2,PRNP,ARF6,ARL6IP5,DNAJC1,CAV1,TMPO,STX6,SLC25A17,LMAN1,ILVBL,CAMLG,COX4I1,HACD3,SRPRA,COQ8A,PTPN1,RAC2,CDCA3,HSD17B11,DHRS7B,FURIN,TP53,CCDC47,PREB,LBR,SRPRB,RAB3B,RIGI,FKBP8,NSDHL,EHD4,EMC2,SNAP23,STX18,UBE2H,EPHA2,VAMP5,RAB2A,HMOX2,DNAJC5,ARL6IP6,RHOJ,COPE,ZNF622,SEC63,UBB,ATL1,CCNF,VAMP3,GSK3A,GP9,SSR1,RPA2,LEMD3,SEC22B,RABL3,ST7,CFTR,CDC42,RPS15,YKT6,TMEM209,FADS2,IRF3,RHOU,RPA3,DERL1,RTN4,RAB9A,RNF113A,SYVN1 |
| 5.058e-13 | -28.31 | negative regulation of multicellular organismal process | biological process | GO:0051241 | 1237 | 478 | 18204 | 5365 |
CHRNA7,GTF2I,EZH2,LHX2,B2M,MIR195,APOC2,PTGDS,SLC6A4,C1QTNF1,MIR28,LGALS3,RAD21,PTGER4,PPARG,MIR503,MIR212,CXCL13,PI16,HOMER3,GPNMB,JUP,MIR106A,TNFAIP8L2,MIR193A,CDKN1B,TSPO,KLHL22,BTG2,UFD1,IL13,MIR34A,SOST,SYNJ2BP,MIR1-1,TNFAIP6,CYGB,TP53,CTSC,STK4,SVBP,IDO1,SDC4,MIR188,BRINP1,MIR133B,TLR4,DDIT3,TRIM27,CDK6,MIR147A,IP6K1,MIR590,PTPN11,KLF4,TOMM70,CCL11,ADORA1,PRDX2,MIR26B,FGFR1,VASH1,RB1,MIR424,TBC1D10C,MIR338,MIR105-1,CXCL10,TNFRSF14,MIR657,CSNK2B,PDCD1LG2,MIRLET7C,CCR2,F2,FOXC2,XAF1,NLRP3,MIR214,MIR17,GJA1,ING1,ATP1A1,CX3CR1,MIR145,NMBR,NKX6-2,MIR640,ROCK2,IL10,MUL1,XCL1,RBPJ,MIR1298,CX3CL1,BRMS1L,ADIPOQ,TNF,RBBP7,MIR505,FGF3,TWSG1,DUSP10,AGER,PLG,PYCARD,MIR361,TRIM46,MIR98,EMILIN1,CDK5,RGS2,PLAC8,BCL6,HFE,EPHA2,CORO1C,MIR495,HMGB1,ING2,CAV3,MSTN,GPR35,MEF2C,CBFB,VGLL4,FKBP1B,FURIN,RC3H2,PRDX4,TYROBP,IFNB1,TRIM11,CPTP,CHID1,MIR146A,PSEN1,LILRB4,PTN,MIR149,FXN,NPTN,MIR504,IL4,MIR31,TCTA,RUNX1,LDLRAD4,IL20RB,SOCS5,MIR208A,AGO1,MIR142,SOCS2,FLCN,MIR302B,SFRP1,MYC,HCRT,DLX1,EPHA4,TLR3,GLRA1,CST3,EFNA3,MIR106B,STK3,HEY2,BTN2A2,MIR194-1,RPS6KA4,LILRB1,MIR132,IL12A,CCL3,HNF1B,CD83,FRZB,ID1,YWHAH,OAS1,MIR488,TMEM176A,CCR1,HDAC5,HGS,TOB2,SAP30L,MIR708,NLRP6,MIR29C,ATP2B4,MIR200C,CD200R1,DLG1,MIR215,ATP1A2,IFRD1,BANF1,DICER1,CBLN1,SNAI2,SOX9,RHEB,NDFIP1,TNR,CTNNA1,GHRL,RGN,MIR20A,IL1R2,PAEP,OTUD7B,ADAMTS1,SPRED2,MIR192,MIR144,DUSP3,TGFB2,CRYBA1,ADRB2,GREM1,ADTRP,PROX1,KLK3,MIR152,CCR7,SEMA5A,RFLNA,MIR25,SPP1,C1QC,DKK1,PTPN22,GCLC,MIR874,UBASH3B,TIMP1,NF2,MIR29A,VEGFA,TFE3,BMPR2,IL23A,PPM1B,MECP2,MIR181C,BMPR1A,FGF23,MIR137,FBXO7,IL15,MIR153-1,NIBAN2,PGK1,TLR8,OPRK1,MIR30E,IRF1,BRMS1,CUL3,MIR100,PIK3R1,NR2E1,LGR4,MIR143,MIR15A,ROCK1,PDCD4,FIG4,PLCL1,IFNG,IL17F,MIR873,MIR34B,LEP,FASLG,KRIT1,CD200,PDE4B,NOVA1,MIR140,THY1,MIR939,PIK3CG,ATF4,FGL2,TFPI,PHB2,ANGPT1,MIR34C,TMEM176B,ADRA1A,SRGN,MTMR2,FGF13,SRI,MIR16-1,NFKB1,ARG2,HPGDS,SOSTDC1,PML,MAP2K6,IL2RA,NPSR1,ACOT13,CTLA4,MIR378A,TRIB1,RNF10,SFTPD,PTHLH,SLC12A2,MIR222,MYLIP,TLR2,G6PD,GADD45A,MIR373,PLN,CD38,CD2AP,THBD,MIR181D,TRIM62,ASB1,SERPINB1,PDCD1,MIR920,CCN3,TUSC2,CRHBP,RHBDD3,DUSP22,MIR24-1,MIR101-1,SMAD3,CERS2,VSIR,STC1,ADIPOR1,STK11,FCGR2B,NOG,EAF2,HDAC6,FBXW7,NKX3-1,NFKBIL1,MINAR1,SAV1,MIR205,MIR197,CD80,MIR129-1,ANXA4,MIR210,UCN,WNT10B,NMI,MIR204,SIN3A,PAX6,MAD2L2,MIR30B,IFNA2,MIR21,MIR96,CD9,INHA,MSX2,SYT4,MIR375,LST1,RGCC,MIR383,PROS1,TIA1,MIR148A,ELAPOR2,RTN4,HDAC3,TNFRSF1B,PYDC2,CD86,MIR107,BGLAP,IL6,ID4,ABHD6,CSK,MIR379,IL12B,MIR185,FGR,NKX3-2,ACVR1C,MIR223,MACIR,FOXP1,GPR37L1,PPARA,PELI1,IFNGR1,GPR137,ADRB1,MIR10A,SPRY1,PRNP,MIR885,LDLR,CD274,FOXP3,HS3ST5,PRL,CD34,RGMA,DEFB114,CRY1,GSK3A,NRP1,PCSK9,PLA2G5,MIR573,NR1H2,MIR125A,BST2,STAT1,ACP5,PTEN,MIR492,CNR1,SOD1,CARTPT,MIR497,MIR130A,TRIM63,MIR155,MIR221,MIRLET7B,IL2,CTDSP1,ARRDC3,GNAI2,MIR206,MIR320A,MIR377,ADRB3,MIR877,RETN,MT3,NPVF,CTSK,GSTP1,CTNNB1,RBBP4,TNFAIP3,CALR,WDR77,PDCD10,SPRED1,PPP1R11,IGF1,SAP30,SDHAF2,DRD3,SELENOS,SMAD4,TLR6,RNF128,STARD13,MIR136,TGFB3,IL1B,WNT7A,PPP3CA,LMNA |
| 5.132e-13 | -28.30 | KIF20A (kinesin family member 20A) | protein interactions | 10112 | 1044 | 397 | 19454 | 5460 |
CSNK1A1,NUFIP2,BORCS6,PACSIN3,PHB2,EEF1G,FXR2,TRA2B,SRSF2,MIA2,DDX5,SF3B1,HERC3,SPECC1L,RPS28,MACIR,DDX39B,H1-1,RPS26,FBXW11,SNRPB,CPSF2,RALGAPA2,BAG3,LRRC8C,HNRNPC,HNRNPAB,MYC,RPL10,ESR2,CBX5,MATR3,SMU1,VDAC2,LIMD2,RPS23,GNAQ,SMARCB1,PDHA1,H2BC1,NUP37,EEF2,H1-3,RPS4X,RUVBL1,HNRNPF,PIK3CG,MYO1B,ABCF1,RPL31,GNA11,TNNC2,ASB7,DDX1,CTNNB1,QPCTL,XPO1,TSPAN10,RPL6,DDX50,BAZ1B,IFI16,HSP90AB1,SNRPD3,HNRNPL,RPS10,PABPC1L,HDHD5,LUC7L3,TFIP11,DDX4,AGO1,ELFN1,WDR3,RPS15,TMEM254,PML,RBM23,DDX46,ABCG2,IGF2BP1,CFL1,CFL2,SMARCA5,TRIM32,DYRK1A,MACROH2A1,GNAO1,ALG2,GNAI3,CAPZA2,CBX3,RPSA,TP53,RPL17,HNRNPK,PSMA5,CYBRD1,DHX9,AKAP8L,H2AC4,SHC1,RPL24,TPM3,ROGDI,RPS27L,ALYREF,RPL32,SSBP1,ACSL4,MFAP1,LARP4B,FEM1A,H2AC1,RASL12,EMG1,TRIM5,RPS5,CCDC25,RHOB,BRCA1,FAM83A,RPS29,PKP4,ERH,PRRC2A,EIF4A2,RPS9,SNRPD1,GNG12,SNRPE,RPS11,RAB6B,ACTN4,TOMM7,FAF2,HSDL2,RAF1,SSRP1,FLOT1,S100A10,ATP5F1D,DHX16,SRSF7,BAG2,MAEA,HNRNPA2B1,HSPD1,HAX1,HNRNPD,INSYN1,HNRNPA1,HSPB8,IFIH1,HMGA1,DHX15,SRSF10,PPIA,INA,RPLP2,MRTO4,RPL9,RPL8,RPL26L1,HNRNPH3,PICALM,STOM,BRIX1,NF2,RPA3,AP2A1,SH3BP5L,MGAT5B,RACGAP1,RPL26,DEK,VIRMA,GNAI2,COPE,MGST3,TMOD3,RPS12,ALB,TRIM27,CTTN,MRPL53,CCNF,NDUFS3,CAMK1,H2AC6,FN3KRP,RPL23A,PPP1R12A,MOV10,KXD1,MRPL50,CGAS,COG1,RPL35A,TNKS,KRR1,HRAS,RPL12,RALYL,CD59,RPL27A,PABPC5,GNB4,STAU1,SSR3,HNRNPA0,DDIT3,P4HA2,XRCC5,POLR1B,FTSJ3,DES,SNRNP40,TRIM29,GPNMB,ATP5F1B,BST2,FAM83B,SF3B4,RPL18,CRKL,ZRANB2,METTL21A,HNRNPDL,RPL28,VDAC1,H1-6,ACTR1B,RTCB,RUVBL2,PABPC1,TOP2B,HSPB1,PPFIBP1,PPIB,HMG20A,LYAR,FAM98A,EED,CORO1C,SRSF1,GNB3,STX17,SAMM50,H2BC11,SPRYD4,CSNK1A1L,SPTBN1,HNRNPH2,BANF1,ZBTB38,DNAJC10,RPS17,RPL10L,TRIM54,ZNF330,RPS3,CARD19,ARPC3,MAD2L1BP,NEFL,IK,H2AX,CAPZA1,PIWIL2,SRSF12,TMEM33,KPNA2,MRPS18B,RPL3,TMOD2,RPL10A,RPS2,SNRNP70,RBFOX3,RBM17,TLR6,TMPO,DKC1,ILVBL,P2RY11,TXNRD3,RPS16,SYNCRIP,MYL6,ATP5PO,RAB6A,PPP1CB,H1-5,G3BP2,COIL,HADHA,CCDC86,GNA14,MYO6,LMNB1,MCM3,MCM4,TOMM40,CUL3,SNRPB2,GNB1,RPL19,CHCHD3,MAD2L1,RBBP4,RPL35,RPL7L1,RPL37A,PIGK,CPSF1,RWDD3,CTSA,EZH2,FAM200A,SNCB,TRIM37,ETFA,G3BP1,RBBP7,SRSF8,RPS24,PPAN,ARGLU1,MORC2,RPL23,FIG4,STOML2,PRPF19,PRDX1,SPTAN1,RPL7,NOP58,LCA5L,RPLP1,PHB1,WDR6,THOC2,MACROH2A2,RPLP0,H2AC7,LMNA,MRPS34,JUP,MYL12B,RPS14,RBFOX2,NHP2,NUCKS1,RPL4,ARPC2,SQSTM1,EGFL7,PRPF4,ATOSB,NONO,PPP1CC,TUFM,ATP5F1A,SEC13,NDUFB10,RPL22,YES1,RPL13A,RAB14,UBASH3B,CHCHD6,RPS20,EIF4A3,PELP1,MSRB3,RNF181,ILF2,THAP1,RPL15,MDC1,PRDX4,RPS13,CTNND1,THRAP3,HAPSTR1,SDHAF1,APOBEC3F,CAV1,ATP5PD,PRNP,TOP1,EIF2B5,PPP1R18,PWP2,SRP14,H2AZ1 |
| 5.243e-13 | -28.28 | CALCOCO2 (calcium binding and coiled-coil domain 2) | protein interactions | 10241 | 482 | 208 | 19454 | 5460 |
ATOSB,LGALS8,BAHD1,PPP1CC,YES1,MAGOHB,RAB14,NDN,PDCD5,TENT2,UBB,OPTN,GSK3A,STOM,DCTN4,LIMS2,RPLP0,FAM161A,EEF1E1,UBA52,SYNGR2,ATG16L1,CDK7,GABARAPL2,UQCRC1,SMCP,GABARAP,RTN4,MAVS,SQSTM1,GPX4,SLC2A1,ZNF688,SETD5,CALR,ORC5,FNDC11,HM13,PRNP,KCTD15,PPP1R18,CAV1,ZBTB2,AKAP17A,ATP5PD,CCT5,TBK1,MAP1LC3B,TOM1,LSM4,MRPL22,ARF4,RAB1A,RPL23A,MYO6,FAM107A,HSP90AA1,CUL3,PRPF31,RIOK2,ACTB,TUBB,STARD7,PRRC2A,CHCHD3,VPS72,ARF1,CDC7,LMO4,PPP1CB,SRI,DUSP26,GPC1,FTL,NRBF2,RNF11,TRAF6,KDM2A,RHOG,DICER1,RB1CC1,PRPF19,ATG9A,HNRNPA1,SPTAN1,PRPF18,PPIA,RPL9,RPLP2,MAP1LC3A,PPID,SCAND1,RPN1,STK16,PLD3,RPS11,MARCKSL1,PPP2R1A,GABARAPL1,G3BP1,TNF,SAR1B,ENKD1,GCA,RPS27A,UBE2A,SRSF7,TNFAIP3,TRIM32,RAB2A,CFL1,CTSB,DUSP3,FKBPL,SRP54,PSMC5,CSNK2B,RPRD1B,RPA2,SDCBP,CYC1,UBE2M,GIT2,SPTBN1,DDIT4L,CDC42,CCNH,LITAF,MARS1,IRF3,LIN7C,RNF34,SHC1,RPS2,USP2,MXI1,SURF6,IAH1,CDK6,RBM34,CBX3,RAP1A,RPSA,MTCH2,NAA35,RRM1,ZNF581,AZI2,HNRNPK,RBCK1,KPNA2,NEDD8,RPL17,PHF1,ZNF451,BCAP29,EFHC1,RAB13,CKB,LMO2,SNRPB,BTF3,CHRDL1,NDFIP1,TAX1BP1,TAGLN2,TAMM41,RPL10,APEX2,SCNM1,TACO1,BST2,UBAC2,MAP2K1,SDC2,ARHGEF39,EEF1G,FXR2,RPS28,HSPA8,FKBP4,IKBKB,STAMBPL1,RAB5C,WWP2,PFDN5,RPL6,YWHAG,LANCL1,HSP90AB1,PEG10,FUBP3,SDC4,CEP57L1,RAB35,TNIK,CORO1C,HDAC11,HGS,SMARCB1,TOP3B,EEF2,TRAF2,PSMA1,RAB18,FAM168A,TRIM21,LDLRAD4 |
| 5.291e-13 | -28.27 | RPL10A (ribosomal protein L10a) | protein interactions | 4736 | 448 | 196 | 19454 | 5460 |
MYC,BTF3,FTSJ3,NSA2,H1-1,RPS26,CMTR1,PRMT5,ZCCHC7,MATR3,RPL10,FBXO42,MTF1,RPL27A,PPT1,PIH1D1,RPS28,HSPA8,HDAC5,STAU1,SSR3,UFL1,WWP2,RPL6,IFI16,DDX50,CTNNB1,DDRGK1,XPO1,NCK1,AGR2,DRG1,LYAR,RPS10,HSP90AB1,MAGEB10,EEF2,MSX2,RPS7,DNAJC25,PDHA1,TUBB4B,RPS23,RPL18,PABPC1,RPL31,H1-6,KRAS,TFG,RPS4X,RPL7A,RC3H2,SPOP,MECP2,UBE2H,PSPC1,RPS3,RPL10L,SRPK2,DYRK1A,CFTR,WWP1,RPA2,ZNF770,KLF4,HEXIM1,RPL27,BAP1,RNF113A,HSPA5,ENY2,COPS5,RPL24,SNRNP70,TUBG1,USP15,RPS2,RPL32,RPS27L,DNAJC1,RPS16,CAND1,FZR1,SURF6,TMPO,RBM42,RPSA,TP53,UBL4A,DNAJC2,RBM34,TFCP2,SNIP1,RPL3,H3C1,RPL17,MEPCE,CUL3,ZNF668,BRCA1,FYTTD1,RIT1,RPS5,SEC61B,RPS9,RPL37A,RPF1,RPL35,ACTB,RPL19,H1-5,EMC9,PPARG,NOP53,UCHL3,G3BP2,MAP3K14,CDK5RAP3,DICER1,RPL23,RB1CC1,MRTO4,PHB1,RPL8,FOLR1,RPL9,RPLP1,RPLP2,RPL7,B3GNT2,OTUD6B,RPL29,CHMP4C,EZH2,SART3,RPS11,TRIP4,SLC25A5,RPS24,TRIM37,S100A10,G3BP1,TNF,UBE2A,RPS27A,PPP1CC,MAPRE1,METAP2,CCNF,PTEN,RPS20,RPS12,PRKRA,RPL13A,RPL22,TPT1,RPS14,CDK7,GRM2,JUP,RPLP0,RPL26L1,ZNF574,SIRT7,RPA3,MTDH,FBXW7,HMGB1,RPL4,NPM3,DGCR8,BRIX1,SPATS2L,GRSF1,MOV10,HDAC6,RCHY1,ACTA2,RPL12,SRPRA,PSMB1,LDLR,RPL35A,MDM2,CDK9,FBP1,RPL15,EEF1A1,SRP72,ILF2,HSD17B10,RPL23A,VRK1,PAK1IP1,HUWE1,RPS13 |
| 5.407e-13 | -28.25 | negative regulation of signal transduction | biological process | GO:0009968 | 1393 | 530 | 18204 | 5365 |
MIR100,NR0B1,CUL3,PIK3R2,BRMS1,PRKACB,YWHAZ,MIR218-1,NIBAN2,LMO3,CCDC3,CTNNBIP1,BPIFB1,FBXO7,NFE2L2,PRELID1,PPM1B,IVNS1ABP,CARD19,RGS6,RNF115,SAMHD1,MIR29A,NF2,UBASH3B,LPXN,MIR874,FAIM,GTF2H2,RB1CC1,PBLD,DAG1,MIR34C,CDK20,SH3BP4,SRC,PHB2,MIR140,PDE4B,ATF4,WIF1,THY1,INSIG2,TNFAIP8L1,SQSTM1,PAFAH1B1,MIR34B,ICAM1,TCIM,RGS7BP,PDCD4,LGR4,MIR15A,CD2AP,CTNND1,CLEC12B,DUSP9,MIR373,MIR222,FKTN,CSNK1A1L,TRIB1,CYRIB,TBK1,PPIF,NHERF1,DUSP6,MAPKAPK5,SOSTDC1,NUP62,PDE2A,MIR16-1,TERT,PIH1D1,OPRL1,MIR205,CLU,BFAR,TXNDC12,CISH,TMBIM6,MINAR1,NKX3-1,FBXW7,NFKBIL1,ATF3,PRR5L,FCGR2B,NOG,CREB3,STK11,STAP1,ADIPOR1,STK38,CCAR2,LMBR1L,SARM1,MIR101-1,MIR24-1,KCTD10,DUSP22,SCYL2,CCN3,TRIM32,CRHBP,TAF9,EGFL7,KBTBD6,DUSP1,LACRT,DDIT4L,TLR9,LEPROTL1,RGS10,HDAC3,SMURF1,PEBP1,HACD3,UBE2B,MCL1,SH2D1A,MIR375,CPNE1,LILRA2,MIR21,MIR519D,PPP1R10,MAD2L2,SIN3A,SAR1B,MIR204,NMI,OPTN,MIR210,VPS18,TPT1,SLC35C1,ZNF592,NDUFS3,HHIP,TCF21,PPP2CB,ENO1,FAM89B,ERRFI1,MIR1224,MIR885,TMEM196,SPRY1,PRNP,MIR449A,PPARA,TMBIM1,PAK5,GPR37L1,FOXP1,YWHAG,MIR223,PEA15,MIR185,BRAP,ELF1,MMP14,UBE3A,IL12B,MOSMO,STAMBP,BAX,IL6,CSK,MMP9,MIR107,PYDC2,ACAA2,PADI2,ADRB3,AATF,XBP1,DLK2,MET,HTRA1,MIR206,GNAI2,PID1,CAAP1,ARRDC3,MIR221,MIR130A,MIRLET7B,UBE2N,AR,UBE2D1,MIR497,RRN3,NCOA5,BCL2L1,PTEN,TSG101,NR1H2,MIR125A,MIR573,STAT1,NRP1,RPGRIP1L,TSPAN15,CDK5RAP3,SYVN1,TMEM88,CRY1,GSK3A,DEFB114,PARL,LMNA,ZMYND11,MIR1271,PPP3CA,HERC4,AKT1,MIOS,NOP53,IL1B,TGFB3,SIAH2,DUSP26,MIR99A,MIR92B,TLR6,DRD3,GPC1,SLC25A31,SDHAF2,SMAD4,TANK,GRB10,SELENOS,SAP30,IGF1,NFKBIA,SNX5,UBE2W,VDAC2,CNOT2,SPRED1,TAX1BP3,BOK,CALR,SIRT7,TNFAIP3,RBBP4,CTNNB1,RGS5,BAK1,HYAL2,GSTP1,INPP5E,KICS2,GPX1,HELLS,UFD1,SLA2,PRKCQ,SESN2,PPP2R1A,MIR106A,HOMER3,SUFU,UFL1,MIR503,PPARG,CSNK1A1,CCDC22,SFRP4,PAQR3,LGALS3,NR4A2,TPBG,EPO,EGR1,TRIM15,CNOT7,YTHDF2,MIR195,LEMD3,FZD6,PYCR1,MIRLET7G,IL7,EZH2,ACKR3,ITGAV,MIR340,PRDX2,PCGF2,MIR26B,PTPN1,NKIRAS1,HSPA8,TMEM14A,NONO,SEC14L1,JADE1,GHITM,IFI6,APLNR,TLR4,EYA3,DHRS3,CER1,DDIT3,MIR133B,CXCL8,MDM2,LPAR1,RGS1,STK4,TP53,ZNF451,TNFAIP6,ITGA6,SOST,SYNJ2BP,MIR1-1,AZI2,SOD2,MIR34A,UBE2D3,YWHAB,MIR214,MIR17,NLRP3,EIF4E2,CASTOR2,ACVR1,PIP4K2C,MIRLET7C,IRF4,RHOH,INPPL1,PSMD10,TMSB4X,HAPSTR1,MDFI,EID2,NKIRAS2,RNF152,MIR424,CGAS,TNFAIP1,TBC1D10C,CITED1,RB1,CTTN,STRADB,GREM2,SLC25A5,NLRP2,STUB1,ABHD17A,BCL6,CXCL12,EPHA2,PFDN5,CTDSPL2,MPIG6B,RGS2,ARHGAP12,EMILIN1,MIR98,FBP1,HECW1,MIR361,MIR23A,PYCARD,DUSP10,CHRDL1,TWSG1,DDRGK1,TNF,ADIPOQ,LBH,RBBP7,BRMS1L,CX3CL1,RAF1,MUL1,IL10,SEC13,SLC25A4,CX3CR1,MIR145,PHB1,ING1,BEND6,TMEM127,HTRA2,LDLRAD4,CNKSR3,SOCS5,HSPA5,MIR342,BRCA1,CD46,FXN,MIR149,IGFBP3,RNF113A,TULP3,MTM1,MIR146A,PSEN1,LILRB4,SOCS3,CAV1,CPTP,TRIM11,MAVS,CDKN2D,MAD2L1BP,VGLL4,TAX1BP1,LYPLAL1,ING2,MSTN,CAV3,DKK3,RUVBL2,FRZB,CYP26A1,MIF,MIR132,INPP5K,SCG2,IL12A,APLN,PELI3,SNIP1,SOCS4,SMAD5,BTN2A2,CSF2,USP15,HEY2,RNF34,STK3,CCL5,G3BP1,RGS19,PEG10,EPHA4,DYRK2,LRRC14,WWP2,DLX1,UBAC2,MYC,IFT172,CSNK1E,IER3,IGF1R,FRMD8,SFRP1,MIR302B,FLCN,PPIA,MIR490,HSPB1,SOCS2,MIR142,DUSP19,IL1R2,ARHGAP25,MIR20A,CSNK2A1,CTNNA1,STAT2,SOX9,ANKRD6,CBL,SNAI2,IFI35,DICER1,DNAJB9,BANF1,LITAF,IGBP1,SLC35F6,CHST11,DLG1,MIR200C,ATP2B4,FKBP1A,MIR29C,NLRP6,H2BC11,KDM1A,TMEM170B,CAV2,MIR708,SAP30L,PRKCB,HGS,RNF126,IGFBP4,OAS1,GCLC,PTPN22,SOX2,DKK1,DYRK1A,ISG15,DDIT4,MIR152,RNF167,GREM1,ADRB2,PAK1IP1,TGFB2,CHP1,MAP2K3,IL1A,DUSP3,CRYBA1,FGF10,SESN3,SHISA2,TLE1,SPRED2,OTUD7B,MIR9-1,NCK1 |
| 5.487e-13 | -28.23 | RPS26 (ribosomal protein S26) | protein interactions | 6231 | 299 | 142 | 19454 | 5460 |
EIF3K,CMTR1,FAU,RPS9,SEC61B,RPL37A,RPL35,RPL10,RPL19,CUL3,ACO2,MYC,RPS29,BTF3,RIT1,H1-1,RPS5,RPS28,PYM1,EP300,HSPA8,G3BP2,NOTCH2,WDR77,RPL27A,PIH1D1,EIF4B,PHB1,RPL8,RPL9,RPLP1,RPLP2,EED,RPL7,DYNC1I2,RPS10,HSP90AB1,RPL6,MAP3K14,DDRGK1,RPL23,BCL2L1,DRG1,RPL31,RPS24,MRPS11,TRIM37,TNF,KRAS,G3BP1,RPS4X,RPS27A,B3GNT2,RPS7,RPL29,ISG15,EZH2,RPS23,RPL18,RPS11,METAP2,CCNF,PSPC1,RPS3,RPS20,PTEN,RPS12,PRKRA,GSK3A,RPL13A,RPL10L,NDN,SRPK2,RPL22,DYRK1A,RPL7A,SLC25A1,NDUFAF2,TUFM,PPP1CC,RPS17,RPL26,FBXO7,SPOP,EIF3G,UBE2H,SIRT7,PNO1,RPA3,RPL27,BAP1,RNF113A,SQSTM1,RPL4,FBXW7,RPS15,TPT1,RPS14,CFTR,METTL14,RPA2,SDCBP,HEXIM1,RPL26L1,RPLP0,RPL32,ACTA2,RPL12,TSR2,TOP1,RPS16,FZR1,MDM2,RBM42,CDK9,MOV10,HDAC6,RPL24,SNRNP70,RPL10A,BRD3,RPS2,DHX9,RPL3,RPL23A,VRK1,RPL17,MEPCE,RPS13,TP53,RPSA,UBL4A,FBP1,RPL15,DDX39A,MAP2K3,TMEM165,DNAJC2,TFCP2,SRP72,OTX2,ILF2 |
| 5.618e-13 | -28.21 | proteolysis involved in protein catabolic process | biological process | GO:0051603 | 597 | 257 | 18204 | 5365 |
ZFAND2A,FBXO9,NEDD8,WDR77,RLIM,PSMA5,PSMD12,PSMD6,ARMC8,KLHL15,PSMA4,CALR,RNF103,TMUB2,FEM1C,PPP1R11,UCHL3,UBE2W,DCAF11,FBXL4,OTUD7B,TNFAIP3,CTNNB1,GID8,CTSK,RNF11,SDF2L1,AKT1,SIAH2,FEM1B,UBE2G2,HERC4,RNF167,DDI1,SELENOS,UBXN6,VPS4B,RNF128,UBA52,FAM8A1,ISG15,RNF8,RPS27A,OS9,PRPF19,CTSB,ANAPC11,FBXL19,TSG101,USP14,EDEM1,DERL1,RNF126,SYVN1,PSMD7,GSK3A,HGS,PSMA3,CBL,SEC61B,NDFIP1,SPSB1,PSMB3,XBP1,TOLLIP,UBE2D1,UBE2N,DNAJB9,UBXN10,TOPORS,PLAA,PSMB1,PSMC3,SKP1,CDC16,UBE2K,ERLIN2,WWP2,UBE3A,RNF14,CDC20,FAF2,FZR1,CHMP1A,UBB,PSMB7,ZER1,RCHY1,FBXO11,USP38,TOM1L1,ANAPC4,HERC3,PPP2CB,RNF122,HECTD3,PSMA6,PELI1,RNF34,FBXO8,UBE2A,KLHL25,RC3H2,CHMP2A,IFI27,PSMB6,KCTD17,ANAPC15,TP53INP2,ERLIN1,RNF7,PMAIP1,BAP1,CHMP2B,MAEA,WWP1,PSMB11,RHOBTB3,UBE2B,KLHL3,SMURF1,HSPA5,ZMPSTE24,PSMB10,SPOP,ECRG4,UBE2S,PSMB2,TRIM26,DNAJB2,JKAMP,DNAJC3,MTM1,UBE2I,HM13,ANAPC2,IDE,KCTD10,GID4,TMUB1,APPBP2,UBAP1,KBTBD6,ELOC,PSMA2,PSMC4,BIRC2,ERLEC1,UBE2L3,TRIM32,FBXO31,UBL4A,DERL2,VPS28,SH3BGRL,ANAPC13,NSFL1C,PSMD4,PSMC1,BFAR,DNAJC10,STUB1,FEM1A,PSMA1,PSMD3,FBXW7,HDAC6,HECW1,RNF5,PML,HSP90B1,RMND5B,FBXW4,CLPX,DISC1,PSMC5,UBXN2B,TNFAIP1,FBXW11,CCNF,MYLIP,RAD23B,NAE1,RNF144B,PSMD14,RNF26,FBXO3,RNF133,RNF40,EDEM2,RNF10,CDC23,PSMB5,CTSC,RNF121,FBXL3,CDC26,SPOPL,MDM2,RNF146,DTL,VPS4A,ADRM1,UBE2D3,ANAPC16,ZFAND2B,CACUL1,TRIM45,FBXL14,CHMP1B,PSMB4,TRIP4,FBXL7,TRIM21,SQSTM1,DDIT3,RNF41,ENC1,ANKIB1,CRBN,HUWE1,RBCK1,SIAH1,CUL2,RNF139,UBE2H,FBXO7,NFE2L2,RNF115,PCYOX1L,SPSB3,CCAR1,FAF1,PSMB9,EDEM3,FBXO22,RNF187,TRIM3,PSMD1,MAN1A2,CHMP5,RNF148,HECTD1,UFD1,KLHL22,RNF20,CCDC47,ZNRF1,COP1,KLF1,CUL3,CSNK1A1,SGTA,FBXO44,CAPN2,AREL1,CHMP4C |
| 5.671e-13 | -28.20 | HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0) | protein interactions | 10949 | 318 | 149 | 19454 | 5460 |
RAB2A,AR,USP14,ATP5F1A,RC3H2,MIR145,UBE2H,DNAJC19,IGF2BP1,EIF4A3,RPS3,MIR16-1,PSPC1,CCNF,EIF4H,NDN,SRC,SMURF1,ATG16L1,SF3A1,MIR34B,MIR1-2,GRM2,LMNA,RPA2,MIR7-1,MIR21,HEXIM1,HNRNPH3,MIR205,MIR10B,RPA3,SQSTM1,GPX4,MIR34C,MTDH,CLK1,MIRLET7I,HNRNPH2,MRPL41,FBXW7,MIR7-3,MIR107,MIR29A,COX5A,DPP4,MOV10,GAPDH,COPS5,HDAC6,SNRNP70,H2AC4,MIR34A,RCHY1,SYNCRIP,MIR106B,LDLR,MIR25,PRR3,MIRLET7G,TOP1,FZR1,RPS16,CAND1,CDK9,RBM42,MIR429,RPSA,TP53,FBP1,MIR200C,MIR15A,MIR20A,MIR17,NUPR1,FURIN,MIR200A,MIR9-3,DHX9,HNRNPK,NEDD8,MIR16-2,MIRLET7C,MEPCE,CUL2,HNRNPC,HNRNPAB,CUL3,MYC,SNRPB,MIR98,FBXW11,BRCA1,CIRBP,THOC6,MIR363,MIRLET7B,MATR3,MIRLET7D,SNRPA,SLU7,DDX5,NMRAL1,SF3B1,STAU1,GPC1,UFL1,MIR106A,MIR143,WWP2,DDRGK1,HNRNPA1,MIR29C,MIR31,MIR140,MIR1-1,MIR221,HNRNPD,SRSF1,NKX3-1,MIR7-2,PHB1,MIR214,MIR141,EED,DYNC1I2,MIR9-1,SUMO2,HNRNPL,CSF2,CACYBP,TOP3B,EEF2,SOX2,MIR222,ABCF1,GADD45A,MIR9-2,HNRNPA2B1,RBM3,ZYX,TRIM11,MIR206,MIR155,KRAS,HNRNPF,SSRP1,HNRNPDL,PSMD12 |
| 5.771e-13 | -28.18 | negative regulation of apoptotic process | biological process | GO:0043066 | 914 | 368 | 18204 | 5365 |
PDCD4,ROCK1,ICAM1,TCIM,NTF4,BIRC5,PIK3CA,KRIT1,PIK3CG,ATF4,HNRNPK,LEP,CD40LG,PHB2,SRC,ANGPT1,FAIM,RB1CC1,TIMP1,BNIP3L,VEGFA,MIR181C,PRELID1,VSTM2L,MECP2,IVNS1ABP,HSPB6,HIGD2A,NFE2L2,FBXO7,RXFP2,NDUFAF4,NTRK2,AREL1,NIBAN2,DDAH2,DNAJC5,MIR30E,YWHAZ,PIK3R1,NR2E1,LAMP3,PTCRA,BIRC2,TFRC,LACRT,TRIM32,GPAM,TAF9,PDCD1,MAGEA4,MIR24-1,SMAD3,CREB3,CCAR2,RGL2,NME2,AKR1B1,NOG,TXNDC12,TMBIM6,CLU,BFAR,TMIGD1,ARG2,NFKB1,PIH1D1,TERT,NUP62,NPPC,HCLS1,CCL2,PPIF,CCL19,VPS54,PIAS1,POU3F4,MIR222,CD38,CD2AP,ACAA2,MMP9,BAX,STAMBP,IL6,FOXP1,NKX3-2,PEA15,PPARA,TMBIM1,PAK5,HAX1,PRNP,ENO1,HSPD1,VDAC1,HYPK,HHIP,NDUFS3,MIR210,UCN,ANXA4,TPT1,BCL2A1,SERPINB9,DSTYK,SIN3A,MIR30B,MIR21,CDC73,PPP1R10,DNAJC3,MSX2,DNAJB6,SFN,GPRASP3,MAEA,UBE2B,RPL10,MCL1,HDAC3,MT3,GPX1,CTNNB1,TNFAIP3,SLC1A1,BAK1,GSTP1,PIK3R3,NAA16,BOK,IGF1,PTRH2,PDCD10,VDAC2,UCP2,SLC25A31,SELENOS,AKT1,NDNF,TGFB3,SIAH2,IL1B,ZMYND11,LMNA,MIR182,WNT7A,PARL,AKR1A1,SYVN1,NRP1,LRP6,BCL2L1,JAK2,LIMS2,STXBP1,SOD1,RRN3,AR,CAAP1,PSMG2,CCND1,TSC22D3,MIR221,PAK2,MIRLET7B,IL2,FAS,EIF2AK2,GNAI2,MTRNR2L3,AATF,XBP1,SOD2,IL13,MITF,ITGA6,IDO1,TP53,ST6GAL1,MAEL,FKBP8,API5,MDM2,DIPK2A,ARF4,NONO,GHITM,EYA3,IFI6,KLF4,SMG9,TMEM14A,MIR590,PTPN1,ADORA1,HSPA8,ACKR3,ITGAV,PCGF2,PRDX2,MGMT,IL7,MTRNR2L7,MIR195,PYCR1,LGALS3,NR4A2,CLN8,MNAT1,RAD21,EPO,FSTL1,FATE1,FCMR,UFL1,RETREG1,PRKCQ,NAA35,NQO1,HELLS,BTG2,CDKN1B,SLC25A4,MSX1,TRAF2,MIR145,CX3CR1,CX3CL1,RAF1,SLC39A10,IL10,PPT1,PTGFR,DDRGK1,TNF,NAA15,HRAS,MIR361,ZNF304,PLAC8,CXCL12,BCL6,ORMDL3,MIR495,DFFA,STUB1,RB1,CTTN,ADNP,CITED1,NPY5R,OGG1,SLC25A5,STRADB,ASIC2,RAG1,HSP90B1,CDKN1A,PSMD10,CFDP1,UFM1,MIEN1,SLC25A27,FOXC2,AIPL1,ACVR1,NEFL,PRKCA,RNF144B,MIR17,PPIA,DAPK1,HSPB2,CRYAB,HSPB1,NUPR1,PRDX3,MIR142,ZFAND6,SOCS2,MYC,SNCB,IER3,SFRP1,IGF1R,CREB1,MIR126,IL2RB,GLO1,GBE1,DLX1,MIR106B,CCL5,RNF34,CFL1,DAD1,CSF2,SMAD5,IL6ST,MAP3K12,HEY2,BCL10,MIR132,SCG2,CDK1,PELI3,CNTFR,LILRB1,MIF,HNF1B,ST3GAL1,MEF2C,TNFAIP8,ING2,PIM2,CDKN2D,AGAP2,HSP90AB1,PTPRZ1,TAX1BP1,CD28,SOCS3,CAV1,PSEN1,FXN,BRCA1,IL4,HTRA2,HSPA5,TLE1,FGF10,IL1A,DPEP1,KRAS,NOTCH2,HAND2,MTDH,TNFSF18,GREM1,SEMA5A,CCR7,DKK1,GCLC,CEACAM5,COPS5,TWIST2,SHC1,KDM1A,IRF7,MAD2L1,IGBP1,SLC35F6,ADAMTS20,CHST11,BECN1,SNAI2,FZD3,CTNNA1,BAG3,CCR5,SOX9,CBL,MIR20A,RGN,GHRL,CCL21,CSNK2A1 |
| 5.909e-13 | -28.16 | bounding membrane of organelle | cellular component | GO:0098588 | 2198 | 784 | 19108 | 5553 |
GALNT12,ATP6V1C1,SLC31A1,VPS26A,LAMP2,SEMA4C,SEC61A1,GCNT3,SCG3,AQP4,BST2,PPP1CC,ARMC1,MGAT4A,TAPBP,STIM1,GALNT1,RND2,TRAPPC3,LAMP5,STX18,SNX14,SNX20,RAB5A,NOS1AP,NCSTN,HYAL2,ENTPD4,NLRP3,QTRT2,EHD1,ARCN1,CYBRD1,TRIM23,LRP6,EXOC3,SLC15A2,B4GAT1,GLCE,HS3ST5,SVOP,PYCARD,RPS26,TICAM2,TMEM190,QPCTL,MAVS,BNIP3L,HSD17B6,NDUFC2,CHST10,TRAF6,FZD4,PDIA3,PXMP2,TMEM167B,PICK1,DBH,STARD7,GLIPR1,GK2,B3GALT2,RPL27,KPNA2,CAV2,AKAP1,USP8,GOLGA5,SEC61G,ST8SIA4,CD36,ST3GAL5,CHST9,TOMM40L,AQP2,VAMP2,ANXA4,TFRC,CHMP4C,SNX10,PXYLP1,SRI,SNX2,RP9,GPR37L1,OPRK1,GORASP2,PARM1,REEP6,REP15,LST1,CLVS1,SERPINB6,MOXD1,SLC35B3,CYTH2,SLC7A14,MRC1,PNPLA8,LGALS3,TMEM97,MIEF1,CPE,PGAP4,TMEM179B,MINAR2,RB1CC1,SLC35A2,GABARAP,CHCHD6,VMP1,RAB6B,RAB11A,EEF1A1,SYNGR3,FUT8,GABARAPL1,MGAT5B,ZDHHC4,STX10,EMC6,RAB11B,RAB32,CD58,CACNG3,STX5,SNX17,CIDEB,RAB3D,RAB6A,THBD,RSAD2,LY96,SEC63,TUFM,OR51E2,NCALD,VAMP7,PHB2,PDE6A,CNR1,DRD1,B4GALT6,FABP5,IZUMO1,VPS16,B4GALT7,MRLN,WSCD1,LMBRD1,MACO1,PRRT1,TNKS,RAB37,PSEN2,HAS3,C1GALT1C1,CHPF2,STBD1,UNC50,ACP2,RAP1B,TMEM38B,ARFGAP1,MGARP,IRAK4,PML,BACE1,PDCD10,FCER1G,GAD2,TNKS2,SYS1,GPAM,GASK1B,B4GALT4,ST3GAL4,MFN1,LAMTOR2,TLR7,ST6GALNAC3,TMEM199,STOM,UBE2D3,SLC2A3,CDC42,ATP6V0E1,GNAQ,PLN,VAMP8,CAV1,CSGALNACT1,CPT1B,MGST3,MTX2,CAV3,GALNT4,LITAF,BBS5,YIF1A,BET1,TMEM231,TMED9,TMED1,ADCY3,TLR6,RAF1,TOMM6,CPLX3,RHEB,VPS33A,RAB2A,SLC18B1,GPNMB,INPP4A,SNX3,BORCS5,HUWE1,CORO1C,TMED5,RHOG,BECN1,MAP1LC3B,RAB30,TF,TMBIM1,VPS4B,TYROBP,SEC61B,LARGE1,CLCA1,DECR2,CD63,AZIN2,TMEM95,DMPK,PRCP,KLC2,PIP4P2,TLR1,VAMP3,CMTM6,CHMP5,AP5S1,TAFAZZIN,SAR1B,CLVS2,PITPNB,SLC17A5,GAL3ST1,HS3ST3A1,CNP,TMEM203,PEX3,MARCHF5,CSGALNACT2,GALNT17,CYB5B,YWHAB,CREB3L4,LMAN1,USP30,ATRAID,KDELR2,CYP27B1,UFL1,CHST7,TRAPPC4,SV2B,VDAC1,TMEM50B,ST6GAL1,ZDHHC17,RAB23,RPS29,RAB3C,SVIP,SESN2,RAP2A,RAB22A,CFTR,CD1B,TSPAN15,CALR,PROM1,SLC30A5,HBEGF,PIP4P1,HAX1,CYB5A,ARMCX3,DIO3,SLC32A1,GNPTG,RHOB,BAD,RRAS2,NOTCH2,SYT4,APOO,SYNRG,TAB1,HINT2,CYB5R1,ROCK1,PEX5L,TAPBPL,DIPK2A,EXD2,SACM1L,SURF4,UBAP1,RAB4A,TMX3,MGAT1,SNX12,SNX1,NDFIP1,STARD3NL,SNX18,TMED7,VLDLR,AP1M1,MME,CD3G,MAP1LC3A,FAM20B,GNA11,LRRC8A,TMEM45B,PGAP2,TSG101,FLOT1,B4GALT3,RPS28,SIGLEC5,CTSC,COG1,SLA2,RAC2,SYNPR,TOM1,GOLGA7,COPZ2,ZMPSTE24,MOSMO,SGMS1,PAQR3,GOLPH3L,SPHK2,MOSPD1,AP2M1,SYNGR4,SYNJ2BP,HSPA8,LAMP3,FCGR1A,VPS39,ARHGAP1,VPS4A,DRAM1,SPPL3,SLC2A8,UST,SNAP23,ATG9A,B3GALT1,TPST1,OPTN,MPV17,ATP6AP2,SNAPIN,GLIPR2,SPG21,MCL1,TMEM74,IRF7,FCMR,TOMM22,NSG1,UBXN6,NDST3,ZNRF1,AGTRAP,TEX264,FUNDC2,TOMM7,RHOBTB1,DELE1,ST3GAL2,BORCS7,CAMK2G,GABARAPL2,LAMTOR3,PSEN1,RAB14,CD9,STX7,ABHD6,FUT9,CD164,CD46,CYSTM1,CLSTN3,B4GALT1,GRIA2,HGS,RAB33B,MT3,GRIA1,BET1L,FGD2,SLC30A7,SARM1,PGAP3,TAS2R46,HS2ST1,SGIP1,SFXN2,SLC35G2,ANXA7,SLC25A17,COX14,TOMM70,GOSR2,KICS2,BLOC1S2,SNX5,ACOX1,RGP1,FATE1,SLC48A1,EHD3,KDELR1,RAB33A,RAB3B,EVA1A,B3GNT2,TLR2,WDR44,LDLR,AP1S2,NOSIP,SH3GLB1,CD274,SEC22B,PROS1,SYPL1,SERPINA1,RAP1A,CLN8,SELL,SYNGR2,ICA1,ARFIP1,NCDN,RAB18,ACER3,VTI1B,BOK,BORCS8,BCL2A1,GABRA2,CYB5R3,RNF121,CHPF,VDAC2,CHP1,EPHA4,ITM2B,SCFD1,SLC22A17,TMEM115,ACAP2,LHFPL2,TMEM108,ENPP4,VAMP1,RAP2C,SLC25A46,YKT6,WASL,BORCS6,MTCH2,SYP,AP5M1,CD59,SRPRB,MDM2,ORMDL3,SYNDIG1,FOLR1,MARCHF9,DNAJC5,PDLIM4,IFI27,FCGR2A,TSPO,ADRB2,GOLGA7B,DHRS7B,SLC6A4,DYNLL1,ARFGAP3,TASL,TFE3,UBA52,CPTP,ABCC5,CHST13,AP1G2,ARMCX1,MARCHF4,FURIN,RAB9B,SLC35B4,GALNT2,RER1,ATP6V1G2,RHOU,TTC8,EHD4,PLEKHF2,BAK1,ATP5MC3,ARF6,PLAAT3,TFEB,UBIAD1,TTC1,RAB31,DNM2,MUL1,MTARC2,BRI3,CLCN6,HPS6,SLC35F1,SYNGR1,OSBP,RAB1B,VPS18,MYD88,SLC38A7,GOSR1,TMEM30A,PLA2G4B,PCSK9,ATG16L1,CPNE1,TOMM40,ST8SIA5,CHST11,TLCD3B,KLHL12,GNPAT,ATP8A1,RAB3A,ZDHHC15,EXT1,SLC35A1,GJA1,SERINC3,PMAIP1,SCAMP2,DHRS3,RAB13,CCDC47,NDST1,RETSAT,NAPG,SNAP29,ATP2C1,SYNE4,AFTPH,LILRA3,RAB8B,SRPRA,PLEKHF1,TMED3,RNF167,DKK1,SLC35C1,GNB4,FKRP,RRAGA,VTA1,BCL2L1,MARCHF3,GCC1,TOMM20,CTSD,SLC11A2,MIOS,MTMR2,ARHGAP21,TEX261,UBB,NECAP1,STX6,RNF152,DPP4,EMP2,IL15RA,TMEM59L,CTSA,ATL1,TM9SF1,PGR,TAB2,TMEM106B,ST3GAL1,SYBU,RPS27A,LYSET,ABHD17A,RAP2B,HHIP,FAR2,ATP6V0B,DEGS1,PDE2A,WDR83,CD4,JPH4,STX16,CX3CR1,SLC2A1,FAM20C,COPE,HMOX2,ITGAV,SAMM50,CYB561,TMEM59,STK24,TLR4,LDLRAD4,MREG,CXCR1,NEU1,PLEKHA8,FLCN,CD1C,RIC3,B2M,RMDN3,SLC38A9,MCHR1,CHST1,OLR1,CHMP1B,ATP6V1A,MGAT4B,PSENEN,SIGMAR1,NECAP2,ARF4,CD14,TLR8,OSTM1,FKBP1A,MYO1B,DLG4,VAC14,ZDHHC8,WDR11,RAB1A,SNAP25,GPR137,FKBP1B,SNN,FIG4,CHMP1A,UGCG,CLBA1,SYT2,B3GALNT1,ATAD1,MYO6,CD1E,B3GALT4,TBC1D5,WNT7A,OCRL,TRIM37,CISD1,CD1D,SLC35F6,EFCAB7,CASK,KXD1,KRAS,MITF,VPS28,CYTH1,TOM1L1,SCYL2,INPP5E,TNFRSF1B,CREB3,FKTN,NAA60,RRAGB,ABCB9,SLC4A8,CLIP3,AP2S1,CD47,FCAR,AGPAT5,ATP6V1D,SPRED2,PTRH2,BAX,RNASEK,AP2A1,GNAI3,MAN1A2,HRAS,DCAKD,TMEM165,SEC13,FUNDC1,TLR3,TRAF3IP3,ENPEP,KCNH1,RAB27A,TBC1D10C,TICAM1,SLC1A1,PEX13,SLC39A13,SEC23A,ATP6V1G1,CYTH4,PEX26,LAMTOR1,GPR89A,PLD3,STX17,CHMP2B,CD1A,RND3,TLR9,TRAPPC3L,STX12,CNIH1,MMD,AGK,ARMCX2,APH1A,GNB1,ARF1,THG1L,SCAMP5,ACSL4,FUT1,DHRS4,SLC35A5,LAPTM4A,GNPNAT1,RAB5C,PGRMC1,SYN3,TVP23B,ENO1,ARFGEF1,SERPINA5,CHMP2A,CHST2,MCOLN1,NTRK2,SEC61A2,SGMS2,RAB35,CHCHD3,STX1A,SERPINB10,TMEM87A,RAB9A,CDIP1,FIS1 |
| 6.024e-13 | -28.14 | DLST (dihydrolipoamide S-succinyltransferase) | protein interactions | 1743 | 457 | 199 | 19454 | 5460 |
RIT1,MOBP,SCFD1,LMNB1,YWHAZ,MYO6,MCM3,PMPCA,AUH,USP13,MTG2,CHCHD3,UMPS,TENT5C,ATP5PO,TIMM29,PRDX3,ACTL6A,PSMC1,HSCB,CCDC86,EXD2,PPP3CA,MRPS26,HBA1,DDX23,RHOG,SIAH2,STOML2,MTRF1,PRPF19,PDIA3,PPIA,NOP58,INA,HP1BP3,GATD3,PHB1,NGB,EZH2,RPN1,PPP2R1A,E2F4,RAF1,NAA15,HSDL2,FLOT1,IMMP2L,MRPS17,ZBTB16,BAG2,MRPS11,HINT2,HSPD1,SLC25A5,DNAJC19,CHORDC1,TUFM,PYCR2,VIRMA,TECR,ACAT1,EIF2AK2,EIF4A3,MACROH2A2,MTRES1,HNRNPH3,HSP90B1,PICALM,H2AC7,LMNA,CDK1,CDK7,PSMC4,CRYZ,NHP2,PDHB,SQSTM1,RPA3,DNAJC4,DNAJC7,HDAC6,GRSF1,SLC25A12,CWC15,AKAP17A,DBT,TOP1,THOC1,PRNP,AIFM1,MRPL49,ILF2,AURKAIP1,LBR,MRPL11,MDC1,FASTKD5,THRAP3,DNAJC30,HSD17B10,SFXN1,RAB1A,SERPINH1,H2AZ2,CHTOP,H1-10,CCT2,CKB,BTF3,RUSC2,LDHB,MYC,DES,ESR2,TAX1BP1,TAGLN2,ATP5F1B,DLST,CCDC90B,MTG1,VDAC2,TACO1,NCOA5,GRIK1,RALYL,MRPL12,TOMM22,SAP18,EEF1G,BOLA2B,RAB5A,HSPA8,PEBP1,NGRN,HSPB1,YWHAG,RAB5C,CHMP2A,COX14,RMND1,CCT7,RAB1B,CORO1C,ZHX1,MAGED2,MTA2,SMARCB1,PDHA1,CAAP1,TUBB4B,EEF2,SOX2,ETFB,RANBP1,TOP3B,KGD4,GJB1,PDIA6,MYO1B,PABPC1,TOP2B,UBE2H,OAT,SMARCA5,MACROH2A1,SF3B6,UQCRC2,DYRK2,GSTP1,RPA2,CFTR,NTPCR,MARS1,HSPA5,OGDHL,SLC25A51,MRPL40,DLAT,GFM1,PML,TMEM70,H2AC4,CHCHD1,PGAM1,DKC1,TMPO,COX4I1,SSBP1,NUPR1,GFM2,CAPZA2,METTL15,TP53,TNRC6C,RAP1A,ATP5PB,CAPZA1,CLPB |
| 6.132e-13 | -28.12 | Ksr1 (kinase suppressor of ras 1) | protein interactions | 16706 | 228 | 115 | 19454 | 5460 |
RPL32,SSBP1,AIFM1,RPL12,PSMB1,RPS16,HDAC6,CSNK2A1,AKAP8L,DNAJC7,NOSIP,TMX3,MRPS18B,RPL23A,KPNA2,PSMA5,PRDX4,RPL17,MSH6,EIF3E,RPS13,YTHDF2,CCT5,CCDC47,EEF1A1,RPS3,STUB1,RPS20,PPP2R5E,CSNK2B,EIF2S2,PSMC5,RPL22,TECR,RPL7A,SEC13,PSMB2,ST13,NONO,RPL26,DNAJC10,EIF3G,PPM1G,RPL27,MTDH,RPL4,NF2,EIF5B,HSPA5,RPS14,PSMC4,CHMP1A,MRPS34,PSMB5,RPL8,RPL9,WDR6,MAGED2,TCP1,RPS10,HSP90AB1,CCT7,RAB5C,PSMD3,PRPF19,PPIB,YWHAH,HNRNPA1,YWHAG,FKBP4,RPL23,YWHAB,CCT8,RPL31,SLC25A5,BAG2,DNAJB4,RUVBL2,RPAP3,EWSR1,RUVBL1,RFC3,HNRNPDL,ANP32B,RPL28,RAF1,FEN1,PPP2R1A,TUBA1A,TUBB4B,RPS11,PELO,RPS9,TUBB,PSMD6,RPL19,HNRNPAB,HNRNPC,H1-10,YWHAZ,PSMD14,CCT2,DNAJB6,HSP90AA1,RPS5,PSMA3,DDX5,HADHA,HSPA8,HNRNPA0,PSMB3,RPL27A,MAP2K1,KCTD12,MYL6 |
| 6.243e-13 | -28.10 | astrocytoma_Grade_IV | COSMIC cancer mutations | astrocytoma_Grade_IV | 15869 | 4653 | 16828 | 4835 |
XPOT,PDIA3,FRA10AC1,CXCL1,APH1A,NDUFB8,ISYNA1,NAA11,EIF1AD,STX17,LEPR,WNT7A,MSX2,RPRML,NLE1,KRR1,SNAI3,CDC37L1,PELI3,PGBD2,SIPA1L1,STAMBPL1,ZKSCAN1,CLDN14,HSPE1,RPL37A,SERPINH1,TRA2B,RAB4A,SOX21,DHX16,LEAP2,HADHA,LHFPL1,KCNA2,HSPB1,B4GALT6,OR6M1,NUDT16,BRMS1,PAOX,CD3G,CDKL2,CHRNA7,KIF1C,GAS8,TAC1,OPA3,IGFBP4,AKR1C2,LMBR1L,NPVF,SPATA2L,TBCE,IPP,NQO1,OXNAD1,BRI3,HEXA,ADAT1,OCEL1,TMED1,RBM23,FGF17,HBB,NEDD8,CXCR1,PTCRA,TRMT6,NDUFA5,CCL21,KCND2,IL34,DFFA,LPXN,RASGRP2,ST13,POLR2I,CD2,FBXO30,TIGD7,RABAC1,WWP2,UCKL1,ACAA2,RAP1A,PCDHA5,SLC20A2,UBXN10,NUBP2,LDHA,PFDN6,PRCC,GSK3A,THOC1,ABCC5,RANGRF,RC3H2,ATP2C1,FATE1,DNAL4,EXOC2,XPO1,EFHC1,SLC25A32,GJA10,EEF2,THRAP3,RNF103,CREB3,TF,SURF4,INTS10,XPO5,RNF187,APOBEC3C,GPR162,ZNF513,SLC7A4,ZMYND11,GALE,SH3GLB2,EIF2B5,ANKIB1,CIRBP,ENDOD1,CXXC5,OSR2,MOB3C,SPOCK1,PHKG1,LASP1,NEK7,UTS2R,GTF2A1,WBP2,FUT8,GNMT,CCL25,AQP4,TXNIP,CREBL2,WDR37,EIF4EBP3,OR51S1,ZSCAN1,DHX9,SLC39A9,FURIN,PSMD6,IL23A,URM1,CETN3,CACYBP,CTSK,MTAP,RAB3C,PWP2,BATF,TOLLIP,TGFB1I1,DUSP1,STX8,FAM200A,S100A10,NFYA,CPT2,CHST9,ANP32B,NDNF,AP1G2,DCAF8L2,SETD4,LCN6,COX7A1,FBXO9,ACOT13,TMED3,WFDC13,CCND1,RPGRIP1L,OR2W1,KLF10,MPHOSPH10,TMEM33,MRPL47,S100PBP,AP3S2,SCG2,ARHGAP21,RHCG,FAF2,BMPR1A,INPPL1,ING5,MIA2,BACH1,KIF2A,SLC35A2,ARMC8,ENTPD4,ID1,PTDSS1,CYC1,POU1F1,FCAR,NPTN,CCDC42,CRYBA2,DEGS1,DEK,NLGN2,CYP4F8,PRKD3,SLC5A6,SPEF1,SCAMP2,OR52M1,NUP107,CD164,CDKN3,BPGM,PPIB,MRPS25,RBCK1,NFE2L1,NOP58,SPATS2L,AKR1A1,FABP5,MRGPRX4,PGAP2,CTSD,TNFAIP3,ABHD16B,RAP2B,DUOXA2,MTMR12,TRAF7,MMACHC,NOL4,IQSEC1,FYTTD1,SIRT7,RRAGA,ETV6,TAPBPL,H19,SPRED1,NONO,POLL,ALDH1L1,MAK16,TSSC4,EIF4EBP2,OR2A2,ZNF805,HPCA,SV2B,SOST,TCP11L1,NDUFAF2,GPR37L1,SNAPC1,SNTA1,SIVA1,GFOD1,PROX1,FGF13,PRKX,LSM6,ZMAT5,RTP4,SYNGR1,NAB1,ENPEP,CERK,USP39,SLPI,USP38,ZNF174,CDK6,CWF19L1,ESR2,DCAF5,ADCY3,SNRPD2,FAM13B,CLEC12B,SFTPD,INTS12,SOCS2,CYP2D6,CTNNB1,RAB8B,ARMCX1,UBE2A,UBE2D3,ATP6V0E1,CCT2,CHRM4,NHP2,NAIF1,TRIM23,ING1,STRBP,P2RY1,OR8B8,IRF1,CASK,GAL3ST1,OR4D11,LTBR,GRPEL1,TCP11L2,ELMO1,PRPSAP1,GABARAP,FGFR1OP2,NCKAP1,NRP1,CDK5R1,CNIH4,GLUL,LMO4,CLU,ATPAF2,KIAA0232,CCR6,TAAR1,ZMYND19,SLAMF9,XAGE5,ZNF397,APOBEC3A,SEC14L1,ZNF319,ID4,CTNNBL1,GRM2,CYP11B1,PYDC2,GALNT4,IDH3B,SENP5,JAKMIP1,ADGB,GPAA1,TLR3,NCR3,EIF4H,ITK,FAM8A1,LRRC69,SWAP70,MYL12A,CYP39A1,HSD11B1,GNRH2,CHDH,SLC35A1,DHRS4,MEF2A,IMMP2L,RAG1,ENY2,KLK3,SLC30A5,SNAPIN,ZNF304,MRPL50,MRPL24,SLC38A9,IL15RA,OSM,FAM78A,PPP1R2,MIOS,RMND1,CCDC69,PSMA3,AK2,SOCS5,GALNT1,TMEM156,GSTO1,MDM2,MGP,EHBP1,MRPL13,UST,PFDN5,EXOC8,TOM1L2,GNRHR2,LYAR,B9D1,NUDT3,CNP,RND3,DKK3,IL20RB,SF3B4,PRRC2A,DPP10,CRABP2,CDO1,PPIL4,RAB11A,ASMT,CCNI,TLR9,SNX20,FIBIN,L1CAM,AKT1,DLX1,FGD2,APEH,COMTD1,FNDC8,ZNF207,EDF1,TMEM219,ATP6V0B,TMUB1,TRIM3,C1QC,POLR3H,SLC25A31,ZNF671,SLC17A5,LIG3,RPS14,LYPLA1,MEAF6,UGCG,KLK9,PLA2G5,ARHGAP1,DOK4,RNF141,KLHDC8B,TRIM32,PRIM2,SNRNP27,CD99L2,SDR42E1,PDIA6,UBR7,GPR89A,EFCAB7,EXOSC1,ZMPSTE24,E2F6,GFM2,GDI2,MRPL23,BUD31,SRP54,TMX4,CAMK2G,PRMT2,CIB3,TACR3,RPL15,TUBG1,CACNB4,GHITM,SCFD1,TTC4,CCDC47,OR4K1,PYGM,SHC1,FGFR1,HCRT,CAMK2N1,CD200R1,KCNJ11,PPP3CA,CRYGB,FAM89B,PEX3,RCVRN,CCDC127,SLC39A7,SBK2,SORD,PSMB5,MCOLN1,CCT5,ENPP4,SMCP,ANAPC2,FBXO32,AGK,PRPF4,ARMCX5,ZNF593,RAB18,IDH2,FKBP14,AGER,CD58,IMPACT,HNRNPC,SETD5,PTPN1,HECW1,TRIM37,ZBTB38,NFIL3,PGS1,SLC25A21,RBBP7,RMND5B,ARMCX2,SIX5,TRIM21,ACTA2,PPARG,GALNT12,ARFIP1,SPR,RFX4,FRMD8,PKNOX1,ADRB1,ZDHHC14,RBM17,PCDHB8,HEY2,TRAPPC1,CLDN11,PAEP,NIPA2,RABL2B,FAM199X,LRP12,NPY2R,RNASET2,SPTAN1,SLC35E3,ATP6V1G1,MTPN,WDR77,MEST,FZD4,AAMP,ZCCHC10,SYN3,GPBP1L1,MX2,MFSD6L,LYG2,ZNF24,TMEM215,FBXO42,SERPINB10,TSEN54,AZIN1,PSME2,HBE1,ABCB1,AZGP1,INO80C,FGF1,JAK1,LBH,MLF1,GTF2E2,TBC1D10C,CCL19,MAGOH,NKX3-2,DHRS3,DEFB116,TNFAIP8L2,NDST1,KTI12,SMAP2,RAB3B,CDCA3,CSNK2A1,PIWIL4,KPNA1,GRSF1,RARRES2,GNG7,CTNNBIP1,ATF4,KBTBD2,GSTO2,SUPT7L,P4HA2,JOSD1,AFTPH,OR4D9,LSM3,KIT,RS1,LHX2,CDC73,UBAP1,ZYX,CYP27A1,DYNC1I2,S100A6,BTF3,MMP9,ROPN1B,VRK1,PGK1,PACSIN3,HEBP1,SLC7A9,ALKBH4,MYH2,SNAP91,DNAJC5,TMIGD1,ADO,CALHM2,GMPPB,BECN1,LMNB1,TES,CCDC25,CHMP2A,OSTM1,EMP3,HSPA8,CBR4,SLC19A2,VMP1,EWSR1,B9D2,TMEM204,PROS1,GPX3,ABHD14B,MRPS16,EED,ZNF592,MTRF1,CIB2,TRIM24,TGFB3,MRFAP1L1,ACSL4,YAF2,ELP3,OR10G9,TSPAN5,BZW2,RINT1,KHDC1,NAT2,SPECC1L,EIF3K,B3GALNT1,CREB3L4,CD274,FABP7,ZBTB17,BCAP29,RAB40AL,DDX39A,SSU72,IGBP1,AKAP12,SNCG,BLOC1S2,SNAPC3,CDKN2C,COX4I2,CALHM3,LHFPL4,EIF4E,TRIM5,TMSB4X,GOLGA7B,OLFML3,TSPO2,PREPL,THTPA,SH3GLB1,EFNB1,RNF113A,MT1M,DEFB114,IFNA10,TFE3,COMMD8,PELP1,CSNK1A1,ITGA6,RTKN,NTN4,PHYH,FUT9,IL10,UBE2V2,RPLP0,IL18,DERL1,ST3GAL1,SOX2,CSNK1A1L,PCMTD2,STOX2,KLC2,PAX9,STXBP1,MTHFD2L,IRF3,CD36,DPEP1,UQCRH,PRKAB1,RAC2,NDUFB4,LCA5,STK24,PYROXD2,MRPS21,LRP6,PARP11,SLC32A1,POR,ST3GAL5,IFRD2,CEP97,ZNF501,KCNMA1,BCL10,NOS1AP,MBD5,ADPRH,PDHA1,DUSP19,NME1,STMN2,RGS2,DPY30,NR1I2,CNNM4,CDK4,NPR2,KCNK13,TRAF2,RBM7,ABHD4,PCDHB1,BRCA1,STAU1,STOML3,TSN,SERINC3,SLC41A3,FKTN,KLK6,TMED7,DNAJC3,RNASEH1,GPX6,POPDC2,GREM2,TGIF2,RDH10,PRPF19,CREBBP,GPAM,PDCD4,LDOC1,OR4Q3,HTR1F,TRIM54,RPLP2,CDC42SE2,FAM98A,ACBD7,KDM4B,TMEM184B,ZNF287,ACAT1,GIT2,OAS1,NKIRAS1,GTF2B,CXCL3,RUVBL1,SDF2L1,RAB3D,SLC13A5,LAMB2,CLDN4,SLC35D1,SMU1,RMI2,COL1A2,SAT1,R3HCC1,CSGALNACT1,VAMP5,METTL14,EDEM1,GNG2,AMIGO1,JPH4,TOR2A,PTS,MAP3K11,MBL2,ANKRA2,ADIPOQ,ALKBH5,ERH,UHMK1,CRTAP,METTL2A,ABHD6,CLDN1,TFCP2,NDUFAF4,AKAP14,CRYBB2,CCNB1,CTDSP1,FUNDC2,MRPS23,CSRNP1,ZNF862,SYP,ATG4A,SFRP4,CDKN2AIP,RGS7BP,FCN2,RER1,ISG20L2,GPHN,POLE4,HSP90AB1,ATAT1,ARMC7,CIDEB,IPO8,TMSB10,ZBTB5,CCR2,AIF1L,ZC3H7A,DSTYK,TMEM123,APOO,BCS1L,SNX17,GPR137,NRSN2,TMEM144,TOP1,OPRK1,GCNT3,NKX3-1,PGPEP1,F9,CYP2C18,NDUFS8,MYO6,TEX30,SEC61B,GPR65,BCL7B,TOM1,EIF2B3,DNAJC22,TMX3,HTR5A,TCF23,PAPSS2,CHGA,WWP1,CBLN4,RHOJ,HIRA,S100A8,CD47,IFNG,JUN,TMEM50B,CCR3,OGG1,ZNF687,SUMO3,OPHN1,PTGER1,SFT2D2,CMAS,RAB23,DNAJC8,PPDPF,TNFSF18,FAM107A,RNF167,CRYGD,RAB33A,SPTBN1,TNRC6C,RNASEL,CHI3L1,UTP23,FERMT2,EIF3J,TOMM40L,GNPNAT1,GIMAP2,HNRNPK,PAFAH1B3,PRKAG1,NFKB1,SCD5,ACAP2,LHFPL2,FOS,DYRK2,CLDN22,EGLN3,RPL26,OS9,POMP,MRPS28,RIOK2,OAT,CCL8,SLC35E1,RB1CC1,CAPZA2,TPPP,RFTN2,PPID,YPEL5,ATP6V1C1,RCBTB1,GGCT,HNRNPA2B1,MAPK1IP1L,PLA2G15,FANCG,OR2A25,STX6,RNF122,NAPG,KIAA0408,SERPINA5,CREB1,BICD2,TMEM177,FMO2,SQSTM1,GLIPR1,RPP25,RBM12,RAN,PGR,HAND2,BRD9,POLR3B,NPY5R,CXCR4,HSPA14,PAFAH1B2,GTF2F2,DLG4,KIAA1191,CCL17,KCNH1,SLC7A14,DDX42,ATP1A2,PXMP2,PPP1R16A,MT2A,CYB561D2,GMPPA,SPRR1B,RPL6,TUSC3,ADAMTS1,CXCL14,CLDN8,BNIP3L,SESN2,PAPOLB,PLAGL1,TRAM1L1,RFXANK,KLHL15,GCA,ZNF576,ISCA2,UPF3B,RABL3,EHD1,FCHO2,CHST1,MPV17,TRAM2,PPP1CB,SLCO1A2,KCNK10,TMCC2,ZNF609,GJB2,WDR3,MANSC1,KRT7,PLEKHA8,TMEM106C,SRP14,NUS1,ACTR2,FOXS1,PTRH2,TAS2R5,CRYBB3,OR4F6,APLN,TMEM164,SYNJ2BP,ACP6,PIWIL2,SOS2,AKIP1,GYS1,SLC23A2,ROGDI,PGM2L1,GK2,CDKN1A,FOXN2,RBFOX2,SLITRK2,STX18,ORAI3,ELSPBP1,CLIC2,MED11,SDHAF2,PPFIA3,OTUD7B,AMY2B,NDE1,RBMX2,TDRD7,CD2BP2,HMBS,CCDC65,LDHAL6B,SLC4A8,SNIP1,UBE2D1,LY6G5C,FAM168A,ACTL6B,OR5L1,RGS5,INHA,RPAP2,RAB1B,HRH3,ABHD13,ZBTB45,ZCCHC9,SLC43A2,TMEM91,B3GNT2,HIGD2A,TEX12,TOP3B,GRIA2,LRRC24,MRGPRX2,DDX4,CAB39,LIX1,KLK5,TMEM14A,TCEAL7,GDE1,GPX5,PCGF3,CPSF2,CDH8,OR14J1,PNPLA8,MYEF2,TAF5L,MOV10,GLT8D1,UQCR11,NGB,VPS33A,SACM1L,CD226,CRBN,ZFP1,PDYN,B4GALT3,CMPK1,SNRPA,BEND5,VAMP2,CCNF,TRAPPC6B,WDR44,GPIHBP1,CTNNA1,RAB2A,PHYHIP,DYRK1B,WIF1,FN3KRP,ISG15,ACADSB,SNX24,OR10G7,STAT6,FGFBP2,EZH2,ARCN1,KCNIP3,INPP4A,AMT,RAB9B,TXNL1,DERL2,TIMP1,MLF2,PLEKHJ1,ELMOD1,LYNX1,RPL23A,TMEM59,IL6ST,EIF4B,PPP2R1A,SMAD3,PTHLH,MRTO4,SLC25A4,TIMM10,STK38,WEE2,PNP,RAB5C,PCDH19,AP1AR,FOLR1,SLC6A11,RAB37,C1QL1,CSTF2T,PSRC1,IFI35,FBXO25,CAV2,LARP4B,OR2Y1,STX11,SERPINA1,PMP22,MRPL11,SCLT1,DAAM1,LRRTM3,LSM10,ANKRD34B,HSPA13,LMAN1,NPSR1,SH2D1A,SLC11A2,PPP2R5E,UBB,FBXL14,RHEB,OVOL1,DHX15,PSMD4,NPPC,RPS7,RAB27A,GRAP2,RELL2,TRIM15,GPX1,SLC6A6,TCF19,SLC30A7,CCDC134,PDHB,DDX46,OCRL,MLC1,MAT2B,ZNF664,BBS5,XCL1,TSPAN18,RPS6KA4,GANAB,IRAK4,IMP3,UBL3,TMEM30A,AFAP1L2,B3GALT1,COMMD6,KCNJ3,GNPDA1,SNX22,SFXN2,FASTKD5,CST11,NCDN,CYP21A2,GNAO1,NDUFB6,MRPL34,TMEM117,GLRX,TOR3A,CBLL1,UBA3,SRSF7,TAGLN3,STAT2,SAV1,EPCAM,PCDH17,IL22,PRR3,RPL7L1,CSTF3,HENMT1,CSGALNACT2,ST6GAL1,REEP3,TOMM22,BFAR,TMEM179B,OXSR1,ILF2,ORC5,ZNF365,BAG3,TOM1L1,KDELR1,RPS16,KRAS,RRM1,RBM22,ASNSD1,CNTN2,NR2F6,HERC4,DKK1,PSMB1,CRIP1,ZMYM3,CFC1,NDUFAF3,CHPF2,IER2,RND2,PPP1R1B,COMMD3,BMPR2,SCG3,OLFM3,RASD1,CCS,NLRP3,ILDR1,SCGB1D1,SHISAL2B,METTL21A,G3BP1,CHAC2,PSORS1C2,POP5,MFSD5,FGFBP1,MRPL18,NUF2,OR13C8,HINT2,TMEM101,SLC16A1,PCDHB13,RPS27A,DAPK3,DSTN,TPD52,RAPGEF5,ELOVL7,DBT,CCDC86,MTA2,SUFU,MRGPRX3,FBXL19,LAPTM4A,CHCHD4,CHIC2,PGGT1B,SLC38A7,KCNC1,OXTR,NRN1,MAPRE1,CTXN1,GNG10,SMG9,MUL1,SEC22C,ZFAND2A,METAP2,MME,ELMOD2,OR10A4,USP15,FKRP,LPAR2,CNRIP1,APOBEC3G,NTRK2,GNG12,PABPC1,RNF144B,DNAJB9,ARG2,ISX,GAMT,SIAE,GNAZ,RTN4,GLRX5,CLDN3,ADAM21,PTEN,RLIM,INO80E,DEPDC1B,UCN,CRLF3,MGAT5B,PTAR1,THAP7,UAP1,TXNDC12,RWDD3,CENPW,FRRS1,SNRNP48,ATG4C,SDHB,GFPT1,NEGR1,SIT1,FDFT1,RPA3,MOXD1,EPHX1,ABHD5,CXCL13,CKS2,RORB,PPFIA2,CNDP2,FBXW11,CINP,IL1A,BCL7C,OR4D6,THBD,HTRA2,NDUFAB1,SNAP29,JAGN1,TYW5,CBLN2,NUDT12,RPL27A,BABAM1,NEUROD2,METTL15,PGRMC1,PTK7,GPR171,DHX38,LGALS8,COX8A,USP8,TMEM147,NXT2,HNRNPA0,CHST2,IKZF5,RHOBTB1,CD247,FZD3,CDAN1,OPRM1,SPRED2,PCNA,DDX23,PIK3R2,PDE1B,TMEM126B,NDUFS6,CTSC,PCYOX1L,CREG2,PLD3,AGPAT5,DNTTIP1,LRRC3,HR,ARPC3,DKC1,FBXO44,KIAA0513,CCNH,SEMG2,POLA2,UBASH3B,MNS1,POLB,CSH1,BTN2A2,UBL5,IFNB1,ABCG2,LTA,MRPS9,UGT1A1,FAM83C,KANSL3,TOR1B,SPSB3,RPL27,PPP1R1A,MSTN,PRICKLE2,RNF148,MTF1,VGLL2,SLC16A10,DIO1,TRMT112,SYNCRIP,SLC35F2,CLDN9,DDX50,RPRD1A,GTF2H5,VRTN,HINT3,SLC25A10,ZNF821,PLS3,CYP1A1,ST8SIA5,TNKS,SLC22A17,STK4,SPON1,PPP2R2C,BST2,STUB1,PIP4K2C,KLF9,TMEM41A,IL1R2,RBM38,ACVR1C,NKIRAS2,FAM181B,SNRK,TEX264,ST7,AVPR1B,TRAK2,UBLCP1,SRSF2,GSTA1,SERPINB1,DHRS13,PARL,POLR2B,TSNAX,UBIAD1,LRRC61,GTDC1,ATP6V1A,EGFL7,TMEM59L,ACP5,HLF,SERPINC1,REG1B,GPM6B,FBXO22,SLC7A8,RFC3,ACBD6,RNF34,OR4D2,OR10A6,DENND2D,COPS7B,KLF4,ETF1,LRRC8B,TRIM68,ATG7,PREB,TUSC1,NPW,NFKBIA,FAM53B,PRDX1,TAF10,SLC25A12,HMGCS1,AK3,CLCN6,USP16,LTB,PFDN2,TCEAL1,TMED5,HARBI1,SHOC2,HDHD3,DRGX,PSMA1,RPL32,DDRGK1,VEGFA,FAF1,IQCK,TP53INP1,DECR2,AVL9,DTWD1,SMPD2,SOD1,NCBP2,TBC1D13,ATXN10,ASTN1,REN,CCR1,GNPDA2,TMOD2,SOBP,PTPN11,NAPA,NOTCH2,CRAT,TM4SF19,MCM4,SCNM1,DCTD,FAM177A1,STARD4,THOC2,FLOT1,ORC6,DROSHA,NR2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SFTPC,PDSS2,SLC6A4,TOB2,YIPF5,FNTB,NME4,MRPL51,GNG3,CDK5,PATE2,RNF26,MAP1LC3A,RAB13,OR10G2,RPP21,SNAPC5,NDC80,PLAC8,CYB5R3,PC,RAB5A,ZNF526,NDUFV2,NEK2,NDUFB7,F10,KCNA3,SSBP1,PTN,TMEM31,SP4,DYNLT3,ZBED4,OR4N4,WASL,CD79B,SDC4,TMCC1,REP15,GOLGA7,RAB14,BVES,MSX1,CHRM1,IL3,P2RY11,DLG1,TLR6,KCTD9,CD151,RPN1,ZNF507,STAT1,PAX6,MRPS33,LMBRD2,EIF2S1,UGP2,LMO3,DPP4,PRDX2,ASB3,CHMP5,BTG1,ZMYM4,EIF2S2,AGPAT1,CXCR6,GNA14,CISH,TXNL4A,USP14,TSC22D3,NANP,DUSP26,EYA3,ANAPC13,CNTNAP1,TMEM176A,PBLD,HDAC6,RNF39,TOR1AIP2,NUP153,MICB,OTUD6A,STOML2,PPARA,COPS7A,GPR15,RNF20,ACTL9,GTF2A2,SNCB,TPT1,ATL1,RRAS2,FRS3,POLR3F,RPL35,RERG,KCNQ5,TPBG,LILRA1,PDE1A,DAPK1,STXBP6,ZCCHC12,ARRDC3,LRWD1,SLC25A17,NFYB,PSMD14,THY1,YWHAB,TESC,SLC25A44,ZNF692,CDSN,SESN3,MMADHC,TTC1,PRPF31,NR1H2,BMP1,LEPROTL1,TMEM95,SPOPL,SYT2,TBC1D24,ST6GALNAC3,EDNRA,CRKL,ATP1A1,TGIF2LX,STARD13,B4GALT1,PSMA5,AOX1,DNAJB6,ZFAND2B,KDSR,DNAJC27,GCC1,LRRN1,CD1B,STX12,CENPP,RP2,FBP1,TMEM199,GZMK,CNPPD1,NLRP1,NAE1,GSTK1,RPS11,GTPBP1,KCNMB2,TMOD1,TXNRD1,TNFRSF14,KATNAL1,AZI2,ILVBL,ARL15,EGFL8,NUDT5,NDUFA12,MYCT1,ARL10,CBX5,FAM118B,MAGOHB,TM9SF1,COMMD2,PEX5L,UCK1,CDC123,GNAI2,GABARAPL1,CD46,KCNMB1,TRMT1L,HOXB1,NRSN1,RHOB,MAX,OR4K17,TMUB2,CSNK2B,YIPF4,VMO1,TRIM11,MRPS18A,C1QL3,PROM1,MTG1,RPL3,QPCTL,TOPBP1,RBM18,G2E3,GLRA1,E2F4,PLN,CD1D,MYD88,MRPL52,FCF1,GFI1,GLYAT,TMEM209,FLRT2,PPM1G,CDC42EP2,DEDD,BOLA3,FUT1,DOHH,BAP1,RPRM,PLAA,GPR26,IL1B,SYS1,ARL4A,ARFGAP3,LITAF,LRRC4,DRAP1,MEF2C,ELAVL4,SEC61A2,RPS27L,COMT,TESK2,STK11,TNNT2,GOLPH3L,TP53INP2,GPSM3,ZNF175,LAMTOR3,SNRPD3,SEC62,FGF12,GPX4,EXOC1,RIMKLA,FKBP10,PHAX,BAALC,ANGPTL2,TMEM106A,RHCE,LY6G6C,TPSG1,UBN1,UBE2F,CYP17A1,FOXP2,SLC22A12,SNAPC2,RPS5,CCHCR1,CCDC71,PDE9A,SLC1A1,CYTH1,EIF4A3,DDX5,ADNP,LAMTOR1,RAP2C,RGMA,DNAJC10,IRF6,RAF1,GPNMB,PRRG1,SAT2,GTF3C3,RNF14,CSTB,DET1,OR51A4,ZNF330,KLHL7,MCHR2,SCYL2,RPL10L,COG1,PHKA1,MBLAC2,ALG2,CYGB,NUDT9,IL17F,PPAT,TNF,GGH,CHRAC1,CCR4,KLF3,SNRPB2,LZTFL1,TFB1M,SUMO2,CGGBP1,PHF13,RPL26L1,NF2,PARP2,BANF1,ABHD12,CARTPT,SESTD1,FOXA3,KLHL1,TAS2R13,DBR1,GNRH1,WDSUB1,PRKCE,ZNF451,TSPAN17,PRKRA,TMEM170A,RNF133,COX6B2,MT1E,CD81,DPH3,LRRC40,ELK3,CRISP1,POLDIP3,POLR2L,HGS,RHOBTB3,FSTL1,UBE2E2,TYROBP,FHOD3,SLC35B3,WDR11,NHEJ1,PEX13,AIPL1,TBC1D25,NBN,TNFAIP8L1,VMAC,IL2,SEC13,CDC20,WDR5B,ZDHHC4,SNRPG,TIMP4,XRCC5,ACCS,SGMS1,RBBP8,MGAT4A,ATAD1,TRIM45,DUSP21,CYP2C9,IGSF11,MRPS34,CDC7,MPPED2,PRL,FBXO8,NDST3,SLC19A3,OLR1,DLST,GTF2F1,GSTCD,TMED9,E4F1,BCL6,SYNPR,SSX2IP,ZNF263,TPPP3,SGTA,MTDH,USP6NL,SNX10,CA2,MIS12,TMEM89,PRNP,CAND1,HSD17B10,GABRA1,ASPA,BCL9,ELMO2,LYPD6,TRPC1,HS2ST1,GTPBP8,DR1,CBX3,PSD2,ATP1A3,BAX,PEBP4,GH1,NUDT2,NPM3,TMEM38B,TSPAN15,CRTC2,RPIA,VTA1,XAF1,PICALM,COX6C,LST1,PIK3AP1,FEM1C,COCH,SF3B1,TAB1,APEX2,ADORA3,AKR1B1,TMEM47,MAD2L1BP,AP1S2,LY96,ANKMY2,CNN3,ZBTB39,RBM27,CPT1B,PSMC3,CDH11,JAKMIP2,FAM83B,SNRNP40,PIK3CA,IVNS1ABP,NDUFS2,PAIP2,TMEM185A,GXYLT2,KCNJ2,CTU1,EPHA4,GCLC,PSMD10,NPY1R,CPLX3,TNNI3K,LIAS,ARL4D,CITED1,TXNDC17,CDK12,DLK2,PLG,DMTF1,FBXW7,TNFAIP6,PSMB7,ING2,ARL2BP,CHRM3,TSR2,SPP1,FAM149B1,FRZB,PRSS23,GPC1,GPR17,PLCB1,ZNHIT6,YWHAZ,STARD3NL,ABHD8,ICAM2,SLC8A1,OR8H3,CAPN2,LSM14A,BOK,OR6X1,TNR,TM4SF18,SLC29A1,SURF2,MAGED2,GJA1,CCNA2,TM4SF20,REEP4,RNF222,AASDHPPT,MAGEB10,CXCR3,HOMER3,TAF1D,SPATA2,SLCO3A1,ADORA1,SHPRH,KCNJ10,OR4K2,PCGF6,GRM1,FAM81A,EHD4,CEND1,ZNF511,STAMBP,HNRNPF,SLC25A1,TMEM205,NDUFC2,TRIM34,ITGB5,RGL2,BLCAP,ICOS,NINJ1,CAV1,B4GALT4,RPS2,YIPF3,TCEAL8,LXN,MEPCE,EIF3G,UBE2L3,CCIN,PMAIP1,TTPAL,PDE4B,SPEM1,CYP3A43,RAB39B,CSNK1G3,MRPS11,AKR1C1,CNTROB,FTSJ1,HUWE1,ABHD10,PRND,CPLX2,LY6H,TNKS2,LILRA2,HSPB2,STK3,CBLN1,COMMD9,DCAF12L2,PTP4A3,PLSCR1,CREBZF,PAQR3,JAK2,PROK1,TRIM36,MRPS18C,NT5DC1,TMEM127,GSTA2,HCAR1,MCL1,FAM53C,NDUFA1,HFE,DDAH1,GPR35,ZBED1,PNMA3,DPH5,RB1,OIP5,CORO6,TRIM29,RNASEH2C,HSPD1,EIF1AX,TCEA2,LRRC28,PARD6A,TMEM115,NPC2,PIAS1,PNPLA4,CAP2,TMEM81,SAP18,EXOC3,DDR1,TIA1,SPG21,SLC22A6,S100A11,ZNF622,ATG9A,SLC25A27,VPS54,RBMS2,TGFB2,MX1,BOLL,PIGA,GLOD4,THOC3,BTG3,DPEP3,TMEM183A,IGFBP3,GADD45A,GRPR,CD9,RUSC2,OR1M1,ITGB8,BTG2,VAV2,CCDC3,GNB3,NUFIP2,CMC1,HINFP,TMEM229B,TRIM44,LRP10,PAIP2B,NR1I3,FHL3,FAM20B,TICAM2,GPRASP2,PQBP1,PPWD1,NRM,WDR45,THAP8,MPV17L2,CRYBA1,HSPB6,SERTAD2,GNA11,HSPA5,GK5,SSNA1,GLCE,SLC25A24,SPINK9,SUPT5H,PDCL,TRIP4,RPL10,STAR,CD209,ST3GAL2,TAS2R7,FBXW4,P2RY4,IP6K1,IL2RB,PTGFR,OR4D5,TEX261,ZDHHC16,RAP2A,MSH6,MDFI,PPP1R11,GPR160,POLR1D,PSMD3,DTWD2,CNPY3,NCAPG2,SRI,CYP4V2,APLNR,KRTAP8-1,POLE3,OR51E2,GP9,RNF10,CDIPT,TNFSF8,ZNF428,PDE2A,PYCR2,RAB6A,FKBPL,RGN,CTTNBP2,SCAND1,PSMD7,PLAC1,CDK7,SIN3A,CRY1,AIP,CD40,TNFSF15,SLC6A2,PMPCA,TLR8,NOG,ARFGEF1,MED22,SRPK2,TAB2,RGP1,CCDC90B,PIWIL1,TRAF3IP3,TMEM107,RPA2,GADD45G,RNASE9,YPEL4,LDB2,OR4A47,TMEM100,DCTPP1,EID2B,PRCP,CPXM1,CD34,FBXL4,UNC79,THAP1,MAGEC2,PSEN1,OR13A1,LCORL,EDA2R,LMO2,FKBP1B,AQP11,TLCD1,RBP2,SSBP4,CLEC6A,KCTD17,RASSF8,DIRAS2,ACER3,MREG,PFKFB2,EIF5B,ARHGAP12,SRFBP1,ANKRD6,FAM161A,YTHDF2,SLC12A2,RPS20,RUNX1,GJC1,NAA16,MED10,TYMS,TAPT1,ZFAND6,SCML1,PDE7A,DUSP3,SUCLG2,ZNF581,VPS18,GHRL,KIF3C,CIAO1,ATP8A1,KCND3,FUBP3,ROCK2,KRIT1,VPS72,TRAF6,RPL18,TKTL1,GIN1,ETNK2,CCDC106,CLDND1,RPS10,SPRY1,IMPA2,UBA52,ECHDC1,FUNDC1,AP1M1,TMEM196,TADA3,TRAM1,MGMT,SP1,ITM2B,MTCH2,MDC1,TRAPPC6A,LYZ,TOPORS,WSB1,OAZ1,SLC25A5,PRR13,SLC35E4,FAM136A,FAM151B,ZNF518B,CYBRD1,ADCK1,MACROD1,SULT1B1,RPE,KLHL25,OR8B4,TMEM165,IRF7,MFAP3L,FAM3C,PTP4A2,VEZT,SLU7,RAMP3,CYTH4,IFT172,CPNE2,TMBIM1,TOX4,KLRC2,CENPL,NUCKS1,IER3,TRIM26,FEM1B,MRPL9,UBE2G2,MECR,MRPS17,SGIP1,UPRT,SUPT3H,FXN,GMPS,TTC9C,THUMPD1,GORASP2,RXRG,SNAP25,CCR7,IGF1,CMA1,DLGAP4,GRIK1,SNRPE,RRAGB,GALNT2,RASL12,IL18BP,ANXA4,KCTD3,PIH1D1,RDH11,LBX1,NKAP,SSPN,GNGT2,CNPY1,LRRC8A,ELFN2,GALC,RP9,OR5M9,HAUS2,ELFN1,DMPK,MBD3,CDC23,MPG,BRAP,SYNGR3,TANK,GPR34,TBC1D1,XBP1,RPF2,TIMM13,ERCC3,GABBR1,PDLIM4,THG1L,ARHGAP19,TACR1,OSBPL8,CEP57L1,CA14,DIS3L,CEACAM5,NAP1L3,EMILIN3,DRD3,MTA3,CHRM5,NACC2,SEMA7A,NAP1L5,CYB5B,MED4,ZCRB1,BCKDK,TRMT5,OR9I1,HPCAL1,LIPT2,MRGPRX1,CORO1C,RACGAP1,RBM3,RRP7A,CCDC126,STT3A,MAGEA4,PIK3CG,RPSA,NPBWR1,UBE2S,HYAL2,ERLIN2,RHOH,ARHGAP15,TMEM126A,GPR75,SETD3,FOSL2,GNPAT,NDUFAF6,ACP2,ACTL6A,STARD7,ZNF436,WBP11,EGR1,ZNF343,SYPL1,CHTOP,SCN2B,ANKRD10,TEF,TCTA,PCP2,SOD2,ADD2,KLF12,MLN,WDR12,RAB1A,GLO1,PDCD1LG2,VSTM4,AMELX,NEU1,PELI1,PIGK,CNOT8,MAP1B,FBXO31,VSTM2L,AQP3,RIMKLB,PRELID1,ETFA,CD59,ECD,PSMC5,APEX1,PRSS1,AKT2,GAB1,ITPRIPL2,CHST10,KCNG3,SOX9,COTL1,PNPO,OR2D3,GPM6A,TICAM1,HS3ST3A1,RFC4,LCN1,TLR5,DCAF16,SRD5A3,CLRN2,DNM2,OR4K13,REG1A,PLCXD3,C1QL2,MMP20,GTF3C4,SMARCB1,HTR2A,STAP1,ACTR1B,ABCC2,FMO1,STARD5,SUGP1,DEXI,ALG5,LRRN4CL,SSBP2,GDAP1L1,PDCD10,WTAP,RPL31,MGST3,BAD,TSPAN3,PRPS1,HAS3,OLA1,AKR1E2,CRHR1,NOC4L,UQCRC1,SERPINA3,RASSF4,KCTD20,SKAP2,CLK1,RSL24D1,TRAF1,BRS3,ZMAT3,NAA30,C9orf72,PTGER2,CDR2,NETO1,CGRRF1,DDX39B,HSD17B8,IRF9,LSM4,DOK6,SEMA3C,HERC3,PSMB4,CD200,TMEM168,TMEM220,ST8SIA4,USE1,NCK1,LRP3,STRADB,SIAH1,KCTD16,SLC15A1,PLEKHF1,ZBTB6,AHSA1,GPR78,HNRNPAB,TRIM62,ZNF655,TEX19,CDKN1B,CMBL,COX7B2,SCHIP1,HMGN4,MEA1,TAF9,PHOSPHO2,MAT2A,NMRAL1,TRAPPC2L,TMEM198,RFX5,OR6C4,SNX11,RPLP1,MT1X,UBE2V1,SERPINB9,TIMMDC1,HELT,IMP4,PDE6A,CENPM,EMX2,SEC61G,HOXB8,SSH3,GFM1,PRM1,GAL3ST4,ADIPOR1,FZD6,MET,SLC7A11,POPDC3,RETSAT,RANBP1,RBM5,CTLA4,ATF3,PDLIM3,PRSS37,MAP1LC3B,IFRD1,DEFB1,ACSS2,RHOU,DLG3,RPL22,CEBPE,TMEM176B,F2,ESYT1,ARL5B,CAMKV,YKT6,VPS26B,ANKH,AANAT,EDC3,SAP30BP,HAPLN2,WNT2,GMDS,CSRNP3,NRGN,TRAPPC3,LDB1,MFSD3,BIRC5,SNRPA1,SNN,CTDSPL2,CEP70,ABHD2,ARL6IP5,PSMG2,NDFIP1,KDM1A,CCDC22,TBCEL,UNC45A,PRSS35,FKBP2,NUDT1,ISG20,RALB,TMEM87A,GMNN,CYP26A1,LRFN3,TNIK,S100B,PDZK1IP1,OR5K1,PDE6D,OR4B1,UBE3A,LEP,SH3BP4,SMARCE1,PITHD1,TADA1,CETN2,ZC4H2,EFNA5,ASPM,ZC3H14,CBFB,CACNG3,RIT2,SEC22A,MAP2K3,DCTN4,DOK5,LSM12,FIG4,RPL7A,CXXC1,SPHK2,RCHY1,FGR,MRPL12,ARF6,PPT1,B3GALT2,ZDHHC24,FHIT,ARL11,MAP3K3,KRTAP4-1,MRPL16,TECR,RNF7,EZH1,ARGLU1,PNRC1,SLC41A1,LAMTOR2,MFAP1,MXD1,MED29,TMEM106B,UCP2,UBE2I,MID1IP1,TDP1,SPCS1,GLIPR2,PLEKHF2,SERINC1,SNRNP70,MAGEB1,SLC6A7,DICER1,DDIT4L,SAP30,RNASE4,SLITRK5,ZNF362,HBM,POU5F1,FGF16,MSN,RPL19,IL21,KIAA1958,ZNF345,EID2,MAEA,FBLN5,LYRM2,FOXD3,CXCL10,ASCC1,CDH7,SVIP,SMUG1,UBXN2B,DUSP18,TPD52L1,ZNF770,TTR,SEC61A1,RSBN1L,METTL18,GAD2,BGLAP,CDC42SE1,COX7B,NOL12,RHOG,FAM83A,ASB11,SDHC,RGS1,BTBD10,PRDX3,PDCD5,EMILIN1,ZBTB26,LRRC14,THAP6,CKB,TUBA1B,HMGB1,MRPS26,PHF7,GNG11,EIF2B2,ZMYM6,ARF1,ZHX1,KCNIP2,SERTAD1,ERRFI1,FA2H,HNMT,DPAGT1,CTSA,PPIL3,ZCCHC7,PHTF2,GPR83,LPCAT3,TP53TG5,DIRAS3,ATG16L1,SIGLEC5,HDAC11,TTLL10,SKP1,CHCHD2,PRELP,KRT8,PCYT1B,CSF2,GCHFR,GJB1,HNRNPH3,LCP1,AGGF1,IZUMO2,TPST1,ZNF200,RBM41,COPE,SLC25A3,RWDD1,HCFC2,PABPC5,PRKCB,IRF2BPL,LSM5,DCTN3,SUV39H1,RGL1,SEC14L5,RPL4,HBP1,CKS1B,DYNLRB2,FOXC2,CRYZ,CRYBA4,PITPNA,RAB32,BLVRA,APOBEC3B,MLH3,PCBP4,TULP3,HS3ST1,BMPR1B,OR4M1,SPDYE4,ADH1B,SRM,MED27,RANBP10,MPP1,PSMD1,BARX2,IFI16,PTPRZ1,SART3,FAM174A,MYLIP,VPS39,CFTR,INA,ATG3,OR5AN1,CLPX,CLP1,VWF,ATP6V1D,ESD,GPR37,CDKN2D,TMEM39A,ART5,CDK17,PSMB10,MARCKSL1,SDR16C5,IFNAR1,SLA2,PYCR1,THOC6,TNPO2,HINT1,RPAP3,RXFP2,RAB9A,CCL11,OPRL1,HSDL2,LYPLAL1,DYNLL1,ABCF1,DUS4L,PLP2,RNF139,SMG5,NUP62,FMOD,ADRB3,SLC7A1,CA12,TBC1D16,SPATA4,CMTM7,LEMD3,IRF4,CSRP1,CCND3,ARL6,STX5,RAB11B,CYP4F22,MVD,STK38L,ARFGAP1,PIGC,SHC3,CDC26,PREP,DDIT3,SLITRK1,SRP72,FIS1,EDEM2,HCFC1R1,CACNB2,RPL28,LCN15,MB21D2,PGAP3,HM13,BCAS4,TCEA1,MCCD1,SLC39A10,VCPIP1,ALCAM,JUNB,SNRPD1,CCL24,LIPA,RELL1,SMAD9,TIMM17A,RNF182,PTPN5 |
| 6.420e-13 | -28.07 | PTCD3 (pentatricopeptide repeat domain 3) | protein interactions | 55037 | 332 | 154 | 19454 | 5460 |
SRSF1,MIR214,GATD3,HNRNPL,COX14,RMND1,MTRF1,RPL6,MRPS35,HNRNPA1,MAP3K14,TRA2A,DDRGK1,RHOG,POU5F1,MRPS26,ARMC8,HSPD1,HINT2,UBE3A,SRSF7,COX8A,MRPS11,MRPS17,IMMP2L,RAF1,SOX2,RBM38,EZH2,PDHA1,OTULIN,HGS,TACO1,MTG1,CCDC90B,RPS9,RPL35,PARL,PRRC2A,RPL19,ESR2,RPL10,MTG2,AUH,MYC,CUL3,PMPCA,BTF3,SNRPB,PSKH1,MRPS25,FBXW11,MIR363,MCAT,RIT1,NSA2,LCA5,NGRN,SNRPA,EXD2,EP300,UFL1,HSCB,NOP53,STAU1,SYK,LNX2,RFXANK,TIMM29,MED23,FAM3C,COQ8A,MRPS9,SSBP1,AIFM1,SYNCRIP,SRP14,RCHY1,COX4I1,ALYREF,TRMT10B,PRR3,CAND1,FZR1,CGAS,MIRLET7G,RBM42,ZBTB2,MRPS23,GRSF1,CALR,E4F1,TMEM70,CHCHD1,SNRNP70,SSX2IP,DNAJC4,NOL12,TCOF1,MRPS18B,CLPB,H3C1,DNAJC30,MEPCE,MRPS18C,FASTKD5,RPL17,H2BC14,TP53,MRPL11,APOO,AURKAIP1,MIR200C,H2AX,APOBEC3D,METTL15,GFM2,MRPS28,SMURF1,SRPK2,VIRMA,ATF4,TUFM,IGF2BP1,ZBTB38,UBE2H,DNAJC19,PPIG,RPA3,BAP1,SIRT7,MIR205,MIR34C,GFM1,HMGB1,RPL4,SLC25A51,CRYZ,HSPA5,MIR34B,MPV17,PLP2,AGO1,CFTR,RBMS2,KLF12,MRPS34,RPA2,METTL14,HEXIM1,MIR21,ZNF574,KLF4,MTRES1 |
| 6.632e-13 | -28.04 | NMRAL1 (NmrA like redox sensor 1) | protein interactions | 57407 | 236 | 118 | 19454 | 5460 |
GNAI3,PDLIM4,CAPZA2,TMEM165,AGPAT5,EEF1A1,CAPZA1,SMN1,HNRNPK,IMP4,TMEM33,SLC25A32,SFXN1,SLC25A11,DNAJC7,RPS2,GAPDH,COPS5,ACOT8,AKR1B1,HACD3,AIP,HNRNPH3,RPLP0,STX17,SSR1,RPRD1B,LMNA,GALNT1,CFTR,SLC35E1,POLDIP2,MFSD3,PDHB,ATP1B3,HMOX2,PPP1CC,CIAO1,SEC13,RPL7A,PYCR2,RPF2,GNAI2,TMOD3,LDHA,MGST3,SGTA,ALB,SEC61A1,TUBA1B,RPS3,QNG1,STUB1,POLR2C,GNB1L,STX12,PRKAG1,KDELR1,ACTN4,TUBA1A,H1-3,CA8,HNRNPDL,PRPS1,RPS27A,VDAC1,SRSF7,SRSF8,PCNA,HNRNPA2B1,SLC25A5,HSPD1,MED4,TRA2A,NGDN,HNRNPA1,RPL6,PRDX1,NUP35,SRSF10,AASDHPPT,EIF2S1,CORO1C,PPP2CB,RPL8,CSNK1A1,CNDP2,FKBP1A,SLC25A3,SEC22A,PPP1CB,AZGP1,GNB4,NT5C3A,RP2,PHB2,ATAD1,HNRNPA0,NMRAL1,HSPA8,TRUB1,HSDL1,HTRA2,MDH1,PRSS1,THOC6,OSGEP,PSMD14,RFC5,TOMM40,LDHB,GNB1,APEX1,SNRNP40,ACTB,TUBB,EFHD2,VDAC2 |
| 6.710e-13 | -28.03 | PTEN (phosphatase and tensin homolog) | protein interactions | 5728 | 734 | 294 | 19454 | 5460 |
GTF3C3,RPS27A,RFC3,SSRP1,RAD21,ANP32B,AHCYL1,TRMO,TRIM37,PCNA,ZC3H7A,BAG2,SRSF7,HSPD1,SCYL2,SLC25A5,RPS11,OTULIN,RNF126,EZH2,NME1,NGB,FEN1,B3GNT2,CNTROB,DHX15,OPRL1,NOP58,SPTAN1,RPL7,MPP1,TYMS,RPLP2,THOC2,PHB1,DCAF11,RPL23,PPP3CA,UBE2D1,HBA1,HNRNPA1,PRDX1,PIK3R1,PRPF19,PSMD3,TRIM8,IFIH1,CDSN,G3BP2,SKP1,CMAS,GPC1,NOP53,HADHA,THOC3,SLC25A3,USP39,ARMCX3,PRDX3,ACTL6A,COX6B2,TNPO3,SNRPB2,THBD,TUBB,B4GALT3,SNRPD1,RPS9,PELO,CYB5R3,UBE2S,ENO2,HSP90AA1,RPS5,LMNB1,RFC5,HSD17B1,MCM3,USP13,ARF4,RPS13,EGR1,MDC1,MSH6,CAMK2G,FARSA,RING1,RPL23A,PC,HSD17B10,IGF1R,DLG1,ZNF787,TRAPPC13,ILF2,MAP2K3,CCDC47,METTL26,MRPL11,YTHDF2,DBT,MRPS23,CAV1,TNKS,RPL12,SRP14,MAP2K6,PSMD7,HDAC6,SUV39H1,CXXC1,POLDIP2,NPM3,FBXW7,PIK3R2,USP8,SMC4,PPM1G,MME,DVL2,MET,RPLP0,STAMBP,LMNA,JUP,HSP90B1,SLC12A2,TECR,UBE2L3,GNAI2,RPL22,CEP97,LDHA,TXN,RPL13A,YES1,TRIM27,UBE2I,PTEN,RPS20,TRIM24,ACAT1,STUB1,PELP1,EIF2AK2,TUBA1B,EPHA2,STK11,ATP5F1A,RPL26,TUFM,AR,RALB,CSK,RPS4X,RPL28,MYO1B,PICK1,RPL31,CCT8,SMARCB1,CRKL,RPS23,TUBB4B,KDELR1,PDHA1,TUBA1A,EEF2,HSP90AB1,RAB1B,HNRNPL,TCP1,SNRPA1,S100A8,EED,MAGED2,C2CD4C,SIN3A,PTK7,SDC4,FUBP3,CBL,DDX1,DRG1,CTNNB1,QPCTL,DDX50,WWP2,RAB5C,RPL6,PTDSS1,GNB4,MRPS7,PHB2,SERPINB6,HSPA8,YAF2,SNRPA,RFC4,XRCC5,ZER1,CSNK1A1,MXD1,CTBP1,GSTM2,UBAC2,GPC4,RPL27A,SUFU,POLR2B,PPP5C,RPL10,ACAP2,PSMD4,MATR3,FBXO22,NDFIP1,RPS26,THOC6,DNAJB6,CCT2,CIRBP,CHTOP,FBXW11,CXCL1,PCCB,MYC,HNRNPAB,LDHB,TNKS2,RPL17,AKAP12,RBCK1,DHX9,NHERF1,DNAJC2,H2AX,KBTBD4,TP53,CDK4,MYL12A,CAND1,FZR1,P2RY11,MRPS9,ITGA6,RPL32,ALYREF,RPS2,RPL10A,CENPL,SMCHD1,TRAPPC2L,H2AC4,CSNK2A1,EIF4E,ZC3H15,RPS15,KDM1A,EXOSC4,PGK1,BAP1,RPL27,ACACA,SDCBP,RPRD1B,WWP1,ZNF326,HBB,RNF146,SPTBN1,IDE,PPP1R10,SMURF1,ROCK1,BUB3,SEC61A1,MRPS28,CREB1,RPS3,EXOSC1,IGF2BP1,OAT,ANAPC4,SPOP,DNAJC10,RPS17,CFL1,EXOC5,SLC25A1,PSMB2,AKT1,RPF2,SMARCA5 |
| 6.848e-13 | -28.01 | RPS12 (ribosomal protein S12) | protein interactions | 6206 | 297 | 141 | 19454 | 5460 |
PPT1,EMC9,PIH1D1,EIF4B,PAFAH1B1,RPL27A,RND2,STAU1,UFL1,G3BP2,RPS28,PYM1,HSPA8,RHOB,BRCA1,RPS5,RPS26,CUL3,MYC,ACO2,RPS29,BAG3,PSMD1,BTF3,RPL35,TAX1BP1,PSMD4,USP38,RPL19,ESR2,RPL10,FAU,RPS9,SEC61B,SMU1,RPL37A,NDUFS6,CHMP4C,VAMP2,RPL18,RPS23,RPS11,B3GNT2,RPS7,RPL29,SOX2,TRIM37,EMC8,TNF,KRAS,G3BP1,EIF2D,RPS27A,RPS4X,RPL31,RPS24,PPM1B,RPL23,HNRNPD,WWP2,RPL6,DDRGK1,EIF3D,RHOH,RPL7,RPS10,FOLR1,RPL9,GRM2,RPA2,UBE2M,RPLP0,HEXIM1,NFYB,RPS14,ATG16L1,CFTR,FTH1,CDC42,HMGB1,RPL4,RPS15,HSPA5,PNO1,SIRT7,BAP1,RHOU,RPL27,RPA3,RNF113A,RC3H2,UBE2H,DNAJC19,RPL7A,PPP1CC,DNAJC8,FBXO7,RHOJ,RPL10L,RPL13A,RPL22,SMURF1,METAP2,RPS3,CCNF,RPS20,EIF2S2,DNAJC2,SRP72,RPSA,INSIG2,FBP1,UBL4A,RPL15,EIF3E,RIGI,RPL17,RPS13,MEPCE,NAE1,RPL23A,ABCE1,RPL3,SNRNP70,RPL24,RPL10A,BRD3,RPS2,EMC4,ENY2,CSNK2A1,HDAC6,RPS27L,PRNP,FZR1,RPS16,RPL35A,RBM42,RCHY1,RPL12,CD4 |
| 7.173e-13 | -27.96 | PSPC1 (paraspeckle component 1) | protein interactions | 55269 | 489 | 210 | 19454 | 5460 |
WDR3,RPS15,EIF4E,ZC3H15,MARS1,ORC6,RPL27,BAP1,EXOSC4,LSM12,RNF113A,RPA2,ZNF326,HEXIM1,EIF4H,PPP1R10,SRPK2,RPS3,SEC61A1,QSER1,EIF2S2,SRP54,MECP2,EIF3G,PDCD4,IGF2BP1,ELAVL2,UBE2H,RPL7A,ARHGAP21,SRPRB,MEPCE,RPL17,SNIP1,RPL3,MRPS18B,ABCE1,DHX9,DDX42,DISC1,TAF2,RPSA,TP53,COMMD8,RPS16,RPS27L,CD274,SYNCRIP,ALYREF,RPS2,RPL10A,KARS1,PPIL4,UFL1,HNRNPA0,FXR2,TRA2B,EIF1B,SSR3,STAU1,EEF1G,RFC4,HSPA8,P4HA2,EP300,DDX5,EIF4B,NUFIP2,RPL27A,NEK7,LRIF1,PPP5C,RPL10,ESR2,SF3B4,FTSJ3,H1-10,RPS26,RCL1,MYC,HNRNPC,RPL39,RPS4X,RPL28,HNRNPDL,RPL31,PABPC1,TOP2B,DNAJB4,RTCB,SEC61G,PDHA1,RPL18,TRMT1L,RPS7,EIF2S1,ISG20L2,HNRNPL,RPS10,FAM98A,COMMD6,LYAR,PEG10,FUBP3,WDR82,EED,DDX1,DRG1,IFI16,CNOT2,RPL6,BTF3L4,NF2,FBXW7,RPL4,BRIX1,RPA3,PNO1,MTDH,TOX4,LSM2,RPL26L1,RPLP0,RARS1,RPS14,EDF1,EIF3J,ZNF622,RPL13A,VIRMA,RPL22,CCNF,CTTN,EIF4A3,RTRAF,RPS20,ASCC1,CCDC22,SMAD2,CASC3,CDC16,RUNX1,GMPS,PPP1CC,KPNA6,AR,NONO,RPS13,SMN1,EIF3E,PPP1R12A,NKRF,DLG1,RPL23A,LLPH,ILF2,SRP72,CCDC47,CD2BP2,RPL15,TOP1,CDK9,MRPS23,SMAD3,SRPRA,OSBPL8,SPATS2L,HDAC6,LZTFL1,YTHDF1,COMMD2,NUP50,CCDC86,LARP4B,MFAP1,EIF4A2,RPL35,PRRC2A,RPL19,FAU,EIF3K,RPS9,RPS5,CUL3,UFM1,EIF2D,RAD21,IMMP2L,HNRNPA2B1,FAM76B,RPS24,BZW2,RPS11,RAF1,ZNF263,JUN,NUP153,RPL7,NUP35,RPL8,WDR6,RPL9,PHB1,RPLP1,RPLP2,WDR12,RSBN1L,NDC80,HNRNPA1,EIF3D |
| 7.183e-13 | -27.96 | LMNB1 (lamin B1) | protein interactions | 4001 | 590 | 245 | 19454 | 5460 |
KPNA2,RAB3B,CSE1L,HNRNPK,NUP107,ABCE1,NAE1,NUPR1,TFCP2,TFRC,ACTR1A,WBP11,TP53,FAM162A,PREB,DKC1,LMAN1,TMPO,DNAJC1,ARL6IP5,RAC2,CAMLG,CD274,KPNA1,API5,PPIL4,COX5A,DHRS7,DPP4,RNF113A,DERL1,RAB9A,ELOF1,PML,BANF1,TEX264,LEMD3,UBE2M,GIT2,PRKCA,SSR1,RPA2,CFTR,GABRA1,CDC42,GTF3C4,NMI,BCCIP,SRPK2,RSL24D1,KCTD9,MACROH2A1,ZNF330,SF3B6,UBE2H,PDCD4,SPOP,ARHGAP21,ATF4,NDUFAF2,VDAC1,KRAS,ACTR1B,TRIM21,ZRANB2,SMARCB1,FAM136A,RAB4A,PDHA1,DNAJC25,SOX2,SERPINA3,H1-3,SNAPIN,NCSTN,SUPT5H,RANBP1,CCDC181,RHOH,HNRNPL,STX5,EED,RAB35,MAGOH,YWHAB,AGR2,CTNNB1,DDRGK1,XPO1,RAB5C,LAMP2,DDX50,SAP18,STAU1,PHB2,ADRB2,UFL1,PCGF2,HSPA8,DDX39B,BMPR1A,KLC2,ZNF362,SEC62,ZC3H14,UBL3,MTF1,ESR2,KBTBD6,ATP6AP2,CBX5,SNRNP40,GGT7,DLST,CMTR1,LMBR1L,DNAJB6,RCL1,H1-1,NSA2,MDH1,CKB,BTF3,MYC,VRK1,THRAP3,DLG1,SFXN1,NSDHL,PDE6D,FAM169A,DMAP1,MAP1LC3B,LBR,DDX39A,CCDC47,ZBTB2,CDK9,POLR2I,RB1,HSD17B11,RCHY1,PTPN1,H2AZ1,SRPRA,HM13,LAMP3,SLC25A46,TMEM199,H2AC14,GABARAP,TMEM209,PIAS1,YKT6,SPCS2,PRKCB,RPA3,SOD1,HELLS,MACROH2A2,HNRNPH3,GRM2,LSM2,METTL14,JUP,LMNA,CDK1,CDK7,ST7,CCND1,SEC22B,RABL3,ATG16L1,GNAI2,VIRMA,SEC63,TECR,UBE2I,PTEN,TRIM24,CCNF,HMOX2,KPNA6,AR,RUNX1,MCM6,G3BP1,TMT1A,CHMP4C,STIM1,EZH2,RPN1,JUN,FAF2,NUP153,RAF1,MACO1,DIRAS3,SPTAN1,KCTD10,AGK,NOP58,HP1BP3,MAP1LC3A,GJA1,THOC2,PPP3CA,CDK5RAP3,DDX23,RHOG,HNRNPA1,MARCHF5,HMGA1,PXMP2,STX7,ATAD1,UCHL3,NUP50,DCTN3,APOBEC3C,VAPB,AGGF1,RND2,PGRMC1,TOR1AIP2,TNPO3,ERH,CHCHD3,RPF1,ACTB,SEC61B,GPR89A,SNRPD1,RAN,ILK,VMP1,SCFD1,BRCA1,LMNB1,MCM8,RPS29,MCM4,CUL3,RAB11A,MTG2 |
| 7.507e-13 | -27.92 | UBQLN1 (ubiquilin 1) | protein interactions | 29979 | 424 | 187 | 19454 | 5460 |
MYG1,SMURF1,RALA,TXNDC12,ADRM1,PSMC5,PSMA6,IGF2BP1,CALU,TRIM23,TNFAIP3,NAA50,PSMB2,TRIM32,GABRB3,ABCC2,RPS15,LITAF,GHRL,PSEN2,GIT2,CHRNB2,GPX3,VPS4B,GABRA1,SPTBN1,CD99L2,SYNCRIP,DOLK,SMAD4,SNRNP70,SMCHD1,FCGR2A,DEFB115,ZFAND2B,GAPDH,DNAJB2,FAM20C,EDEM1,ADIPOR2,PSMA5,NEDD8,SOD3,PAQR9,PSMC3,TMEM31,PLAAT3,GPR162,ZMYM4,ZMYM3,UBL4A,INSIG2,PSMB6,PSMD4,PSMD6,ZMYM2,LMBR1L,FGF7,ZNF343,PSMD14,PSMD1,OST4,PSMA4,EP300,PYM1,HERC3,IL6ST,NEK7,PSMB3,RPS10,DYNC1I2,RNF144B,SMAD9,AGR2,PPIB,SYNJ2BP,WWP2,DCTPP1,FKBP2,PSMA1,PSMA2,RPL31,ABCF1,ZRANB2,MOB3C,HGS,KDELR1,PSORS1C2,RPS7,CSTF2T,MIEF1,OR4N2,UBB,CD47,GNPDA1,UBE2I,APOC4,OPTN,GABRA2,TNFRSF1B,COL1A2,ATP5MC1,RPL26,CSK,FAM163B,DESI1,SOD1,LMNA,MANBAL,GRM2,CCL3,PSMC4,TPT1,EEF1E1,UBA52,SCG2,PSMB1,H2AZ1,SCG5,PPIC,PSMD7,GLO1,DEXI,PSEN1,FBXO25,TICAM1,SEM1,RPL23A,IGF1R,TLR4,SFXN1,GABRB2,RAD23B,HSPA13,UBE2B,MLLT6,MAP1LC3B,AGPAT5,ZDHHC4,UBE2V1,H2AJ,COMTD1,JPH4,GNB1,TENT5C,DYNLL1,PNMA1,RNF208,FAS,SLPI,LMNB1,SRGN,PSMC1,CDSN,NT5C3A,UCHL3,PTN,HSCB,PSMA3,WBP2,APOC2,PSMB7,TMUB2,GKAP1,NDE1,NPY,SPTAN1,HYPK,MAP1LC3A,RPLP2,PSMB5,PSMB4,UBE2D1,PSMD3,VPS26A,CDIP1,RPS27A,UBE2A,PSMD12,AHCYL1,SAR1B,COPS4,ERP29,UBE3A,SMIM19,RPN1,CYB5R1 |
| 7.522e-13 | -27.92 | rectum | COSMIC cancer mutations | rectum | 15837 | 4645 | 16828 | 4835 |
ZNF207,EDF1,ATP6V0B,TMEM219,TRIM3,C1QC,TMUB1,POLR3H,ZNF671,SLC25A31,SLC17A5,RPS14,LIG3,LYPLA1,MEAF6,UGCG,PLA2G5,KLK9,DOK4,ARHGAP1,RNF141,KLHDC8B,TRIM32,CD99L2,PRIM2,SNRNP27,SDR42E1,UBR7,PDIA6,GPR89A,ZMPSTE24,EXOSC1,E2F6,GFM2,GDI2,MRPL23,PSMA3,CCDC69,GALNT1,AK2,SOCS5,TMEM156,GSTO1,SPRN,EHBP1,MDM2,MGP,MRPL13,PFDN5,EXOC8,UST,TOM1L2,LYAR,NUDT3,CNP,RND3,SF3B4,IL20RB,DKK3,CRABP2,RPS23,DPP10,PRRC2A,CDO1,PPIL4,RAB11A,CCNI,TLR9,L1CAM,SNX20,DLX1,AKT1,APEH,FGD2,COMTD1,FNDC8,CYP11B1,PYDC2,GRM2,CTNNBL1,IDH3B,GALNT4,SENP5,GPAA1,JAKMIP1,ADGB,TLR3,ITK,EIF4H,NCR3,FAM8A1,LRRC69,SWAP70,HSD11B1,CYP39A1,MYL12A,GNRH2,CHDH,DHRS4,SLC35A1,IMMP2L,MEF2A,RAG1,ENY2,SLC30A5,KLK3,ZNF304,MRPL24,MRPL50,IL15RA,OSM,SLC38A9,MIOS,PPP1R2,FAM78A,RMND1,UBE2A,ARMCX1,CCT2,CHRM4,ATP6V0E1,UBE2D3,NHP2,NAIF1,TRIM23,OR8B8,IRF1,ING1,P2RY1,STRBP,CASK,OR4D11,GAL3ST1,LTBR,ELMO1,GRPEL1,TCP11L2,PRPSAP1,GABARAP,FGFR1OP2,CDK5R1,NRP1,NCKAP1,CNIH4,GLUL,LMO4,KIAA0232,ATPAF2,CLU,CCR6,TAAR1,SLAMF9,ZMYND19,XAGE5,APOBEC3A,ZNF397,ID4,SEC14L1,ZNF319,KPNA1,PIWIL4,CSNK2A1,RARRES2,GRSF1,ATF4,GNG7,CTNNBIP1,GSTO2,KBTBD2,SUPT7L,JOSD1,P4HA2,OR4D9,AFTPH,LSM3,RS1,KIT,LHX2,UBAP1,ZYX,CDC73,CYP27A1,S100A6,DYNC1I2,BTF3,MMP9,VRK1,ROPN1B,PGK1,SLC7A9,PACSIN3,ALKBH4,HEBP1,SNAP91,MYH2,DNAJC5,TMIGD1,ATP6V1G1,MTPN,WDR77,FZD4,MEST,AAMP,MX2,GPBP1L1,SYN3,ZCCHC10,MFSD6L,LYG2,ZNF24,FBXO42,TMEM215,TSEN54,SERPINB10,AZIN1,PSME2,HBE1,AZGP1,INO80C,ABCB1,FGF1,JAK1,LBH,GTF2E2,MLF1,NKX3-2,MAGOH,CCL19,TBC1D10C,DHRS3,TNFAIP8L2,DEFB116,NDST1,DNAL1,KTI12,SMAP2,RAB3B,CDCA3,SETD5,HNRNPC,PTPN1,ZBTB38,HECW1,TRIM37,NFIL3,PGS1,RBBP7,SLC25A21,RMND5B,ARMCX2,ACTA2,SIX5,TRIM21,PPARG,GALNT12,ARFIP1,SPR,FRMD8,RFX4,ZDHHC14,ADRB1,PKNOX1,PCDHB8,RBM17,HEY2,TRAPPC1,RABL2B,PAEP,NIPA2,CLDN11,FAM199X,NPY2R,LRP12,RNASET2,SPTAN1,SLC35E3,CAMK2G,TMX4,SRP54,BUD31,TACR3,CIB3,PRMT2,CACNB4,RPL15,TUBG1,GHITM,TTC4,SCFD1,CCDC47,SHC1,OR4K1,PYGM,FGFR1,HCRT,PPP3CA,CRYGB,KCNJ11,CD200R1,PEX3,FAM89B,RCVRN,SLC39A7,SORD,SBK2,MCOLN1,PSMB5,CCT5,ENPP4,AGK,ANAPC2,FBXO32,PRPF4,ZNF593,ARMCX5,RAB18,FKBP14,IDH2,CD58,AGER,IMPACT,GALE,SH3GLB2,EIF2B5,CIRBP,ANKIB1,ENDOD1,OSR2,CXXC5,MOB3C,LASP1,PHKG1,SPOCK1,NEK7,UTS2R,GTF2A1,WBP2,FUT8,GNMT,CCL25,CREBL2,TXNIP,AQP4,GLE1,WDR37,EIF4EBP3,OR51S1,ZSCAN1,FURIN,SLC39A9,DHX9,PSMD6,IL23A,PCDHA5,SLC20A2,UBXN10,PFDN6,LDHA,NUBP2,GSK3A,ABCC5,THOC1,RANGRF,RC3H2,FATE1,ATP2C1,DNAL4,XPO1,EXOC2,GJA10,EFHC1,SLC25A32,KIAA0040,THRAP3,EEF2,CREB3,RNF103,TF,INTS10,SURF4,XPO5,GPR162,APOBEC3C,ZNF513,SLC7A4,ZMYND11,BRMS1,PAOX,CD3G,CHRNA7,KIF1C,GAS8,CDKL2,LMBR1L,AKR1C2,NPVF,IGFBP4,TAC1,OPA3,TBCE,SPATA2L,NQO1,IPP,OXNAD1,BRI3,OCEL1,ADAT1,HEXA,TMED1,RBM23,HBB,FGF17,NEDD8,CXCR1,PTCRA,NDUFA5,CCL21,KCND2,IL34,DFFA,LPXN,RASGRP2,ST13,CD2,POLR2I,TIGD7,FBXO30,WWP2,RABAC1,ACAA2,RAP1A,UCKL1,PDIA3,FRA10AC1,XPOT,CXCL1,ISYNA1,NDUFB8,APH1A,NAA11,LEPR,STX17,WNT7A,MSX2,NLE1,KRR1,CDC37L1,SNAI3,PELI3,PGBD2,STAMBPL1,SIPA1L1,CLDN14,ZKSCAN1,HSPE1,RPL37A,SERPINH1,RAB4A,SOX21,TRA2B,DHX16,LEAP2,HADHA,LHFPL1,B4GALT6,HSPB1,KCNA2,GXYLT1,NUDT16,OR6M1,PROX1,PRKX,FGF13,ZMAT5,RTP4,LSM6,SYNGR1,NAB1,ENPEP,VPS4A,USP39,CERK,SLPI,USP38,ZNF174,CDK6,CWF19L1,DCAF5,ESR2,FAM13B,SNRPD2,ADCY3,CLEC12B,SFTPD,SOCS2,CYP2D6,CTNNB1,RAB8B,ZBTB42,TNFAIP3,ABHD16B,RAP2B,DUOXA2,MTMR12,MMACHC,TRAF7,IQSEC1,NOL4,FYTTD1,ETV6,RRAGA,TAPBPL,SPRED1,NONO,POLL,TSSC4,ALDH1L1,MAK16,EIF4EBP2,OR2A2,HPCA,SV2B,ZNF805,TCP11L1,SOST,GPR37L1,SNTA1,SNAPC1,GFOD1,SIVA1,EMC4,INPPL1,MIA2,BACH1,KIF2A,ARMC8,ENTPD4,SLC35A2,PTDSS1,ID1,POU1F1,CYC1,CCDC42,NPTN,FCAR,CRYBA2,DEGS1,NLGN2,DEK,SLC5A6,PRKD3,CYP4F8,SPEF1,OR52M1,NUP107,SCAMP2,CD164,BPGM,CDKN3,PPIB,MRPS25,RBCK1,NFE2L1,AKR1A1,NOP58,SPATS2L,MRGPRX4,FABP5,CTSD,PGAP2,CETN3,URM1,CTSK,CACYBP,RAB3C,MTAP,PWP2,TGFB1I1,DUSP1,TOLLIP,BATF,STX8,S100A10,FAM200A,NFYA,CPT2,CHST9,ANP32B,AP1G2,NDNF,DCAF8L2,OTUD6B,SETD4,LCN6,FBXO9,COX7A1,WFDC13,ACOT13,TMED3,RPGRIP1L,OR2W1,CCND1,KLF10,TMEM33,MRPL47,S100PBP,MPHOSPH10,AP3S2,ARHGAP21,SCG2,RHCG,BMPR1A,FAF2,PLAGL1,PAPOLB,SESN2,TRAM1L1,RFXANK,KLHL15,GCA,ZNF576,RABL3,UPF3B,ISCA2,EHD1,MPV17,FCHO2,CHST1,TRAM2,PPP1CB,SLCO1A2,KCNK10,ZNF609,TMCC2,MANSC1,WDR3,GJB2,KRT7,PLEKHA8,TMEM106C,NUS1,SRP14,ACTR2,TAS2R5,OR4F6,CRYBB3,APLN,TMEM164,ACP6,SYNJ2BP,KIAA0408,RNF122,CREB1,SERPINA5,BICD2,FMO2,TMEM177,GLIPR1,SQSTM1,RAN,RPP25,RBM12,LCN9,BRD9,HAND2,PGR,POLR3B,CDH13,NPY5R,HSPA14,CXCR4,GTF2F2,DLG4,OR2H2,PAFAH1B2,CCL17,KIAA1191,KCNH1,SLC7A14,DDX42,PXMP2,ATP1A2,MT2A,PPP1R16A,GMPPA,CYB561D2,RPL6,SPRR1B,TUSC3,CXCL14,ADAMTS1,CLDN8,BNIP3L,PRKAG1,HNRNPK,PAFAH1B3,NFKB1,SCD5,MAFG,ACAP2,LHFPL2,FOS,DYRK2,EGLN3,OS9,RPL26,POMP,OAT,MRPS28,RIOK2,CCL8,NAA60,RB1CC1,SLC35E1,CAPZA2,TPPP,RFTN2,PPID,YPEL5,ATP6V1C1,GGCT,RCBTB1,HNRNPA2B1,TAPBP,MAPK1IP1L,PLA2G15,FANCG,STX6,OR2A25,WWP1,RHOJ,CBLN4,CD47,HIRA,S100A8,JUN,IFNG,TMEM50B,OGG1,ZNF687,CCR3,SUMO3,OPHN1,PTGER1,RAB23,CMAS,DNAJC8,PPDPF,TNFSF18,FAM107A,RNF167,CRYGD,RAB33A,SPTBN1,TNRC6C,RNASEL,CHI3L1,UTP23,GIMAP2,GNPNAT1,FERMT2,EIF3J,TOMM40L,TXNL1,DERL2,TIMP1,PLEKHJ1,MLF2,ELMOD1,RPL23A,LYNX1,IL6ST,TMEM59,EIF4B,PPP2R1A,SMAD3,SLC25A4,MRTO4,PTHLH,STK38,TIMM10,WEE2,PCDH19,PNP,RAB5C,AP1AR,SMN1,FOLR1,RAB37,SLC6A11,C1QL1,FBXO25,PSRC1,IFI35,CSTF2T,CAV2,VPS33A,SACM1L,CD226,CRBN,ZFP1,PDYN,B4GALT3,SNRPA,CMPK1,BEND5,CCNF,VAMP2,TRAPPC6B,WDR44,CTNNA1,RAB2A,PHYHIP,DYRK1B,FN3KRP,WIF1,SNX24,ACADSB,ISG15,OR10G7,STAT6,ARCN1,EZH2,INPP4A,KCNIP3,AMT,RAB9B,ZCCHC9,SLC43A2,TMEM91,TEX12,HIGD2A,B3GNT2,TOP3B,FLYWCH2,LRRC24,GRIA2,MRGPRX2,DDX4,CAB39,LIX1,KLK5,GDE1,TCEAL7,TMEM14A,GPX5,PCGF3,CDH8,CPSF2,OR14J1,MYEF2,PNPLA8,TAF5L,MOV10,UQCR11,GLT8D1,NGB,SOS2,PIWIL2,AKIP1,SLC23A2,GYS1,PGM2L1,ROGDI,CDKN1A,GK2,RBFOX2,FOXN2,STX18,ORAI3,ELSPBP1,SLITRK2,MED11,CLIC2,SDHAF2,OTUD7B,PPFIA3,AMY2B,RBMX2,NDE1,TDRD7,CD2BP2,HMBS,LDHAL6B,CCDC65,SNIP1,SLC4A8,LY6G5C,UBE2D1,ACTL6B,FAM168A,RAB1B,RPAP2,OR5L1,INHA,RGS5,ZBTB45,ABHD13,HRH3,NOS1AP,BCL10,KCNMA1,MBD5,PDHA1,ADPRH,DUSP19,NME1,STMN2,RGS2,NR1I2,CNNM4,CDK4,NPR2,RBM7,TRAF2,KCNK13,PCDHB1,ABHD4,BRCA1,STAU1,STOML3,TSN,SLC41A3,SERINC3,KLK6,FKTN,RNASEH1,DNAJC3,TMED7,IL18,DERL1,ST3GAL1,CSNK1A1L,SOX2,KLC2,PAX9,STXBP1,STOX2,ERV3-1,IRF3,CD36,MTHFD2L,UQCRH,DPEP1,PRKAB1,RAC2,LCA5,STK24,PYROXD2,MRPS21,TAS2R40,LRP6,PARP11,SLC32A1,FAM163B,POR,ST3GAL5,IFRD2,CEP97,ZNF501,BZW2,TSPAN5,OR10G9,RINT1,NAT2,KHDC1,SPECC1L,CREB3L4,B3GALNT1,EIF3K,CD274,FABP7,BCAP29,ZBTB17,DDX39A,RAB40AL,IGBP1,AKAP12,SSU72,BLOC1S2,SNCG,SNAPC3,COX4I2,CDKN2C,LHFPL4,CALHM3,TRIM5,EIF4E,TMSB4X,GOLGA7B,TSPO2,OLFML3,THTPA,SH3GLB1,PREPL,RNF113A,EFNB1,IFNA10,MT1M,DEFB114,TFE3,COMMD8,CSNK1A1,ITGA6,PELP1,HOXD12,NTN4,RTKN,FUT9,PHYH,IL10,UBE2V2,RPLP0,CALHM2,GMPPB,LMNB1,BECN1,CCDC25,TES,CHMP2A,OSTM1,EMP3,HSPA8,VMP1,CBR4,SLC19A2,EWSR1,TMEM204,GPX3,PROS1,MRPS16,ABHD14B,EED,MTRF1,ZNF592,ACSL4,TGFB3,DTYMK,MRFAP1L1,TRIM24,CIB2,YAF2,ELP3,APOO,SNX17,BCS1L,GPR137,NRSN2,SRRM5,TMEM144,TOP1,GCNT3,OPRK1,NKX3-1,F9,PGPEP1,NDUFS8,CYP2C18,MYO6,SEC61B,GPR65,BCL7B,TOM1,EIF2B3,TMX3,HTR5A,TCF23,PAPSS2,GBE1,CHGA,MRPS23,FUNDC2,CSRNP1,SYP,ATG4A,ZNF862,SFRP4,RGS7BP,CDKN2AIP,FCN2,RER1,ISG20L2,GPHN,POLE4,HSP90AB1,ATAT1,ARMC7,CIDEB,TMSB10,IPO8,ZBTB5,AIF1L,ZC3H7A,CCR2,DSTYK,TMEM123,SLC35D1,SMU1,RMI2,COL1A2,SAT1,CSGALNACT1,METTL14,VAMP5,EDEM1,GNG2,JPH4,AMIGO1,TOR2A,PTS,MBL2,MAP3K11,ADIPOQ,ANKRA2,ERH,ALKBH5,UHMK1,CRTAP,LCP2,IK,CLDN1,ABHD6,METTL2A,TFCP2,CRYBB2,AKAP14,NDUFAF4,FAM162A,CTDSP1,CCNB1,GPX6,POPDC2,GREM2,TGIF2,RDH10,LDOC1,GPAM,PDCD4,PRPF19,CREBBP,OR4Q3,HTR1F,TRIM54,RPLP2,CDC42SE2,ACBD7,FAM98A,KDM4B,TMEM184B,ZNF287,ACAT1,GIT2,OAS1,NKIRAS1,CXCL3,GTF2B,RUVBL1,SDF2L1,RAB3D,LAMB2,SLC13A5,CLDN4,SLC25A12,HMGCS1,CLCN6,AK3,LTB,PFDN2,TCEAL1,USP16,TMED5,HARBI1,SHOC2,HDHD3,PSMA1,RPL32,DDRGK1,FAF1,VEGFA,TP53INP1,IQCK,AVL9,DECR2,DTWD1,TBC1D13,NCBP2,ATXN10,SOD1,ASTN1,SMPD2,CCR1,REN,TMOD2,GNPDA2,PTPN11,SOBP,NOTCH2,NAPA,CRAT,TM4SF19,PARL,DHRS13,UBE2W,TSNAX,POLR2B,LRRC61,UBIAD1,GTDC1,ATP6V1A,EGFL7,TMEM59L,HLF,SERPINC1,ACP5,GPM6B,REG1B,FBXO22,RFC3,SLC7A8,ACBD6,RNF34,OR10A6,OR4D2,KLF4,DENND2D,COPS7B,LRRC8B,ETF1,TRIM68,ATG7,TUSC1,NPW,NFKBIA,PREB,FAM53B,PRDX1,TAF10,DDX50,RPRD1A,GTF2H5,HINT3,SLC25A10,VRTN,ZNF821,PLS3,ST8SIA5,CYP1A1,TNKS,SLC22A17,STK4,SPON1,PPP2R2C,BST2,PIP4K2C,STUB1,KLF9,TMEM41A,IL1R2,RBM38,FAM181B,NKIRAS2,ACVR1C,SNRK,TEX264,AVPR1B,ST7,TRAK2,SERPINB1,GSTA1,UBLCP1,SRSF2,KIAA0513,SEMG2,CCNH,UBASH3B,POLA2,POLB,MNS1,CSH1,UBL5,BTN2A2,IFNB1,MRPS9,LTA,ABCG2,UGT1A1,FAM83C,KANSL3,TOR1B,SPSB3,PPP1R1A,RPL27,MSTN,RNF148,PRICKLE2,MTF1,SLC16A10,DIO1,VGLL2,SLC35F2,TRMT112,SYNCRIP,CLDN9,TIMP3,PPP3R2,PRSS12,PRMT6,PMM2,TTL,TMEM70,VAMP8,MPDU1,PPAN,IL2RA,SF3B5,RCL1,KLHL24,FKBP8,GABPA,PPP2CB,ZNRF1,CHST13,AQP2,SMAD1,HP,CTTN,STOM,RPL23,CLLU1,SPIN3,ANP32A,FBXO7,RABGGTB,SLC2A3,SEMA4C,METTL22,CYP2C8,ASZ1,CAPN1,USP3,TGFBR2,CEBPG,CDNF,TNFRSF1B,LAMP2,TMEM237,RNASE1,TMEM45A,CGB8,FAM43A,NLRP9,LLPH,GSTP1,CCL2,OR8B12,PPM1K,AR,IFI6,EFNA3,TPM3,SNRPB,ELOVL1,MORC2,SSR2,SOSTDC1,RIT1,OR10P1,CHRNB2,GPX7,PTPN4,HSD17B6,PLCB2,MAP2K1,APOBEC3F,FPGT,LRRC3B,OTX2,EIF4A2,MAGEH1,PRDM4,FEZ1,STAT5A,COPS5,ADAMTS10,MRPL20,EP300,RNF8,PEA15,CHKB,CCNY,ELF5,CLDN12,GPR176,PKP4,SCML2,DNAJC19,VGLL4,FCGR1A,GSTM5,ERAS,MYBL2,PLEKHO1,ZNF326,CRHBP,CNOT2,OTOS,ODAM,VDAC1,CLPB,FEN1,KLF1,PRKACB,ASB7,GLRX2,LANCL2,APOBEC3H,ADD1,JKAMP,CLEC2B,SEPHS2,CBR3,MCM4,SCNM1,DCTD,FAM177A1,STARD4,THOC2,ORC6,FLOT1,NR2E1,DROSHA,KLHL22,MAVS,UBP1,IGF1R,SLCO2B1,CX3CR1,PDAP1,SOX14,CEP19,CHMP4C,CDCA7L,MRPL22,SS18,CD1C,UMPS,NUDT7,IFIH1,FCGR2B,MTM1,BIRC2,RFXAP,EPS8,UPK1A,HOXC4,SIAH2,CHCHD6,POLR1B,CER1,METTL21A,PSORS1C2,POP5,CHAC2,G3BP1,MFSD5,FGFBP1,MRPL18,HINT2,OR13C8,NUF2,TMEM101,SLC16A1,PCDHB13,RPS27A,DSTN,DAPK3,ELOVL7,RAPGEF5,DBT,TPD52,SUFU,MTA2,CCDC86,MRGPRX3,LAPTM4A,FBXL19,CHIC2,CHCHD4,SLC38A7,PGGT1B,KCNC1,OXTR,OXSR1,ILF2,ORC5,BAG3,ZNF365,KDELR1,TOM1L1,RBM22,RRM1,RPS16,KRAS,CNTN2,ASNSD1,NR2F6,HERC4,DKK1,PSMB1,CRIP1,ZMYM3,NDUFAF3,CHPF2,IER2,RND2,PPP1R1B,BMPR2,COMMD3,SCG3,OLFM3,RASD1,CCS,ILDR1,NLRP3,SCGB1D1,IRAK4,IMP3,UBL3,TMEM30A,AFAP1L2,KCNJ3,COMMD6,B3GALT1,GNPDA1,SNX22,SFXN2,FASTKD5,CST11,NCDN,CYP21A2,GNAO1,NDUFB6,MRPL34,TMEM170B,TMEM117,GLRX,TOR3A,CBLL1,UBA3,SRSF7,PCDH17,EPCAM,STAT2,SAV1,TAGLN3,IL22,PRR3,RPL7L1,CSTF3,HENMT1,CSGALNACT2,ST6GAL1,REEP3,BFAR,TOMM22,LARP4B,STX11,OR2Y1,SERPINA1,PMP22,MRPL11,SCLT1,DAAM1,LRRTM3,ANKRD34B,LSM10,HSPA13,NPSR1,LMAN1,SH2D1A,SLC11A2,PPP2R5E,UBB,FBXL14,RHEB,DHX15,OVO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P4C,NRBF2,PPIG,UBFD1,GSTM2,NAA35,COMMD5,SST,PFDN4,GABRA2,RAB30,RSAD2,NICN1,NPY,SLAIN2,CAMLG,PLA2G12A,CNR1,TAS1R2,ZBTB2,MFN1,DAD1,RFC2,SNX18,TYW3,LNX2,MATN4,DDAH2,ACTB,ZER1,CNTN1,GNB4,CPNE1,CHCHD3,NFKBIB,ZNF280B,MMP21,EID1,EPO,RPS13,UGDH,PGAM1,AP2S1,RNF121,PTPN22,SOCS3,FOLR2,PDRG1,DCUN1D5,PPIH,HDDC2,HSP90AA1,CD1A,LPAR1,FZR1,DRD1,SLC22A8,SMAD4,SLC1A3,GPR85,PPP2R3A,ATP1B1,ELK4,FAIM,SMARCA5,CNPY4,IL1RAP,VKORC1L1,DRAM1,FXR2,AKR7A2,FOXP4,RNF126,TMEM182,LDHB,RPF1,GPBAR1,ITGAV,USP5,MXI1,FERD3L,LRRC1,NUP37,TCEANC2,TM9SF4,FCHSD2,ISCU,ELAVL2,OR5AP2,MOSPD1,UBE2M,PIR,SLC6A12,TRIM10,UBE2E3,AGAP1,KBTBD4,PNO1,CYP2F1,PSME1,CLVS1,FAU,RAB22A,AK5,TNNC2,GTF2E1,OR8I2,SMC4,DNTT,OSBP,GOLGA5,RLN2,OR9K2,NDUFS3,HPGDS,TTC32,PAIP1,SSRP1,OCIAD2,TWSG1,MED21,PSMC1,TBC1D4,RPAIN,GIMAP4,MORN4,RERE,GRID1,PPP1R12A,CCDC122,IL6,HSCB,SYVN1,CES5A,TFEB,ARMC1,GABRB2,LGR4,HECTD1,DYNC1I1,TLR2,FGF10,FTL,TMC7,LRIF1,STIM1,GRPEL2,FLRT3,TNFSF13,CD248,ZNF668,RSRC1,RPL35A,MSL2,CXCL12,FLCN,SLC25A28,SLC39A3,SERPINI1,PPM1D,IDO1,KLHL12,SPATA6,FAM162B,GLT8D2,VTI1B,ARHGAP5,MRPS7,CCL20,ZNF575,LIN7B,PCDH9,ZRANB2,ARHGAP25,DES,RIC3,TCAP,MYOZ3,EIF4E3,NDUFB10,POMT2,POLR2F,PADI2,SCPEP1,OGN,NSFL1C,NUP50,IFNGR1,NDUFA2,RIMS4,NMI,SCN3B,OSGEP,LRRC57,PLSCR4,MOG,IL15,MRPL10,YBEY,NTPCR,PNOC,CYP27B1,HMG20A,BTF3L4,TLE1,ARL6IP6,UTS2,RRN3,DHPS,NIF3L1,TMEM14B,GNG5,CD2AP,SRC,VPS28,MPZ,KRTAP12-4,IFNA2,IDH1,TUFM,OR51M1,GNG13,RASL10A,METTL6,TERT,SLC35B4,MKKS,LANCL1,PIK3R3,MORC4,CISD1,PIP5K1A,IZUMO1,PEG10,PSMB6,ZCCHC17,BAHD1,DHRS7B,PTGER4,TOMM20,TRAF3IP2,CHRDL1,HNRNPD,PDCD1,MS4A7,KCTD15,PAFAH1B1,SLC25A11,CKLF,CCT7,PSMD12,RGS19,RCE1,MGAT1,RASGRP3,ENTPD3,CDC42EP3,RNF115,MCM3,RAB33B,SECISBP2L,IFIT2,SH3BP5L,MED31,FCGR2A,NAA50,CELF6,RPL7,YTHDF1,TUBA1A,CHST11,HMX2,UNC50,ICAM3,LUM,CCDC85B,SEMA6C,NEUROG2,MTMR6,PDE2A,ZNF428,TNFSF8,CDIPT,PYCR2,CTTNBP2,RGN,FKBPL,RAB6A,PLAC1,SCAND1,PSMD7,SIN3A,CDK7,CRY1,CD40,AIP,SLC6A2,TNFSF15,PMPCA,TLR8,ARFGEF1,MED22,NOG,SRPK2,TAB2,RGP1,CCDC90B,TRAF3IP3,PIWIL1,TMEM107,RPA2,RNASE9,GADD45G,LDB2,YPEL4,DCTPP1,TMEM100,OR4A47,PRCP,EID2B,CPXM1,THAP1,UNC79,FBXL4,CD34,GLCE,SSNA1,GK5,SLC25A24,SUPT5H,PDCL,TRIP4,RPL10,STAR,ST3GAL2,TAS2R7,CD209,FBXW4,P2RY4,IP6K1,PTGFR,IL2RB,ZDHHC16,OR4D5,TEX261,MSH6,RAP2A,PPP1R11,MDFI,POLR1D,GPR160,DTWD2,PSMD3,SRI,NCAPG2,CNPY3,APLNR,CYP4V2,POLE3,KRTAP8-1,GP9,OR51E2,RNF10,FAM133B,ITGB8,BTG2,VAV2,CCDC3,GNB3,HINFP,NUFIP2,TMEM229B,TRIM44,LRP10,NR1I3,FHL3,TICAM2,FAM20B,PQBP1,GPRASP2,PPWD1,NRM,THAP8,WDR45,MPV17L2,CRYBA1,HSPB6,GNA11,SERTAD2,HSPA5,RNASEH2C,HSPD1,EIF1AX,LRRC28,TCEA2,PARD6A,NPC2,TMEM115,NUPR1,PIAS1,PNPLA4,CAP2,TMEM81,EXOC3,SAP18,DDR1,SPG21,TIA1,SLC22A6,ATG9A,ZNF622,S100A11,VPS54,SLC25A27,TGFB2,RBMS2,MX1,BOLL,PIGA,GLOD4,THOC3,BTG3,TMEM183A,DPEP3,GADD45A,IGFBP3,GRPR,RUSC2,CD9,OR1M1,TTC9C,PELO,GMPS,THUMPD1,GORASP2,RXRG,SNAP25,CCR7,IGF1,DLGAP4,CMA1,GRIK1,RRAGB,SNRPE,GALNT2,IL18BP,RASL12,ANXA4,KCTD3,PIH1D1,RDH11,LBX1,NKAP,LRRC8A,SSPN,CNPY1,GNGT2,HAUS2,OR5M9,GALC,ELFN2,RP9,DMPK,ELFN1,CDC23,MBD3,MPG,BRAP,TANK,SYNGR3,WSB1,TOPORS,LYZ,OAZ1,SLC25A5,PRR13,SLC35E4,FAM151B,CYBRD1,MACROD1,ZNF518B,ADCK1,RPE,SULT1B1,KLHL25,TMEM165,OR8B4,IRF7,PTP4A2,FAM3C,MFAP3L,SLU7,VEZT,CYTH4,CPNE2,TMBIM1,IFT172,RAMP3,KLRC2,TOX4,CENPL,TRIM26,NUCKS1,IER3,FEM1B,MRPL9,UBE2G2,MECR,SGIP1,MRPS17,FXN,UPRT,SUPT3H,ROCK2,KCND3,FUBP3,VPS72,KRIT1,TBCCD1,TRAF6,RPL18,GIN1,TKTL1,CCDC106,ETNK2,CLDND1,RPS10,SPRY1,IMPA2,FUNDC1,AP1M1,ECHDC1,UBA52,TRAM1,TADA3,MGMT,CCSER2,SP1,MTCH2,ITM2B,MDC1,TRAPPC6A,PSEN1,MAGEC2,OR13A1,LCORL,EDA2R,FKBP1B,LMO2,RBP2,AQP11,TLCD1,SSBP4,RASSF8,CLEC6A,DIRAS2,MREG,ACER3,ARHGAP12,EIF5B,PFKFB2,SRFBP1,FAM161A,ANKRD6,PDE12,YTHDF2,SLC12A2,RUNX1,RPS20,GJC1,NAA16,TAPT1,TYMS,MED10,ZFAND6,SCML1,PDE7A,DUSP3,SUCLG2,ZNF581,VPS18,GHRL,CIAO1,ATP8A1,KIF3C,PSD2,GH1,BAX,PEBP4,ATP1A3,NUDT2,NPM3,TMEM38B,TSPAN15,GSTM4,CRTC2,RPIA,VTA1,PICALM,LST1,COX6C,XAF1,PIK3AP1,FEM1C,COCH,APEX2,ADORA3,SF3B1,TAB1,AKR1B1,TMEM47,MAD2L1BP,LY96,AP1S2,ANKMY2,CNN3,CPT1B,ZBTB39,RBM27,CDH11,PSMC3,JAKMIP2,SNRNP40,FAM83B,PIK3CA,IVNS1ABP,NDUFS2,PAIP2,TMEM185A,GTF2F1,DLST,GSTCD,E4F1,TMED9,SYNPR,BCL6,SSX2IP,ZNF263,TPPP3,SGTA,USP6NL,MTDH,CA2,SNX10,MIS12,TMEM89,HSD17B10,PRNP,CAND1,GABRA1,ASPA,BCL9,LYPD6,ELMO2,TRPC1,HS2ST1,GTPBP8,DR1,CBX3,TYROBP,WDR11,NHEJ1,FHOD3,SLC35B3,AIPL1,PEX13,TBC1D25,NBN,VMAC,TNFAIP8L1,IL2,SEC13,WDR5B,ZDHHC4,CDC20,SNRPG,ACCS,TIMP4,XRCC5,SGMS1,RBBP8,MGAT4A,ATAD1,TRIM45,DUSP21,IGSF11,CYP2C9,MRPS34,CDC7,MPPED2,PRL,FBXO8,NDST3,OLR1,SLC19A3,NUDT9,CYGB,IL17F,PPAT,TNF,GGH,CCR4,CHRAC1,KLF3,LZTFL1,SNRPB2,TFB1M,SUMO2,CGGBP1,PHF13,RPL26L1,PARP2,NF2,ABHD12,BANF1,CARTPT,SESTD1,KLHL1,FOXA3,TAS2R13,DBR1,ZNF451,PRKCE,WDSUB1,GNRH1,TSPAN17,PRKRA,COX6B2,RNF133,MT1E,ELK3,CRISP1,LRRC40,DPH3,CD81,HGS,RHOBTB3,POLR2L,POLDIP3,FSTL1,UBE2E2,TRAPPC13,TNKS2,LILRA2,LY6H,HSPB2,COMMD9,CBLN1,STK3,DCAF12L2,PLSCR1,PTP4A3,CREBZF,PAQR3,JAK2,PROK1,NT5DC1,MRPS18C,TRIM36,GSTA2,TMEM127,HCAR1,MCL1,FAM53C,ALG11,NDUFA1,GPR35,DDAH1,HFE,CTXN3,ZBED1,DPH5,PNMA3,RB1,TRIM29,CORO6,OIP5,NDUFC2,TMEM205,TRIM34,ITGB5,RGL2,BLCAP,ICOS,NINJ1,CAV1,B4GALT4,RPS2,YIPF3,TCEAL8,LXN,MEPCE,CCIN,UBE2L3,TTPAL,PMAIP1,PDE4B,CYP3A43,SPEM1,RAB39B,CSNK1G3,MRPS11,AKR1C1,SREK1IP1,CNTROB,FTSJ1,HUWE1,ABHD10,CPLX2,PRND,YWHAZ,STARD3NL,ICAM2,ABHD8,OR8H3,SLC8A1,LSM14A,CAPN2,BOK,OR6X1,TNR,TM4SF18,SLC29A1,SURF2,GJA1,MAGED2,CCNA2,TM4SF20,RNF222,REEP4,AASDHPPT,MAGEB10,CXCR3,HOMER3,TAF1D,SHPRH,KCNJ10,SLCO3A1,SPATA2,ADORA1,OR4K2,GRM1,PCGF6,FAM81A,EHD4,CEND1,ZNF511,STAMBP,HNRNPF,SLC25A1,GXYLT2,KCNJ2,EPHA4,NPY1R,GCLC,PSMD10,CPLX3,TNNI3K,ARL4D,CITED1,LIAS,CDK12,DLK2,PLG,DMTF1,TNFAIP6,FBXW7,PSMB7,ING2,ARL2BP,CHRM3,TSR2,SPP1,FAM149B1,FRZB,PRSS23,GPR17,GPC1,PLCB1,ZNHIT6,BTBD10,PDCD5,PRDX3,EMILIN1,ZBTB26,LRRC14,CKB,TUBA1B,THAP6,HMGB1,PHF7,MRPS26,GNG11,EIF2B2,ZMYM6,ARF1,ZHX1,SERTAD1,KCNIP2,ERRFI1,FA2H,HNMT,CTSA,DPAGT1,PHTF2,ZCCHC7,PPIL3,GPR83,LPCAT3,EID2,ZNF345,KIAA1958,FBLN5,FOXD3,LYRM2,MAEA,CXCL10,SLC37A4,CDH7,ASCC1,SVIP,SMUG1,UBXN2B,DUSP18,TPD52L1,ZNF770,SEC61A1,TTR,METTL18,RSBN1L,GAD2,BGLAP,CDC42SE1,COX7B,RHOG,NOL12,FAM83A,ASB11,RGS1,SDHC,ARL11,FHIT,MAP3K3,KRTAP4-1,TECR,MRPL16,RNF7,EZH1,ARGLU1,PNRC1,SLC41A1,LAMTOR2,MXD1,MFAP1,UBE2I,UCP2,TMEM106B,MID1IP1,SPCS1,TDP1,GLIPR2,PLEKHF2,SNRNP70,SERINC1,SLC6A7,MAGEB1,DICER1,SLITRK5,RNASE4,SAP30,DDIT4L,HBM,FGF16,MSN,POU5F1,ZNF362,RPL19,IL21,LRFN3,TNIK,S100B,PDE6D,PDZK1IP1,OR5K1,OR4B1,UBE3A,SH3BP4,LEP,PITHD1,SMARCE1,ZC4H2,TADA1,CETN2,CBFB,ZC3H14,EFNA5,ASPM,CACNG3,IFNA13,RIT2,DCTN4,SEC22A,MAP2K3,DOK5,LSM12,FIG4,CXXC1,RPL7A,SPHK2,RCHY1,MRPL12,FGR,PPT1,B3GALT2,ARF6,ZDHHC24,CYP4F22,STK38L,MVD,PIGC,ARFGAP1,SHC3,CDC26,PREP,SLITRK1,DDIT3,SRP72,FIS1,EDEM2,RPL28,CACNB2,HCFC1R1,MB21D2,PGAP3,TCEA1,HM13,BCAS4,SLC39A10,MCCD1,VCPIP1,JUNB,ALCAM,SNRPD1,CCL24,LIPA,RNF182,TIMM17A,SMAD9,RELL1,PTPN5,MARCKSL1,IFNAR1,SDR16C5,SLA2,PYCR1,THOC6,TNPO2,HINT1,RPAP3,RXFP2,RAB9A,CCL11,OPRL1,LYPLAL1,HSDL2,DYNLL1,PLP2,ABCF1,DUS4L,RNF139,SMG5,NUP62,ADRB3,FMOD,TBC1D16,SLC7A1,CA12,CMTM7,SPATA4,LEMD3,IRF4,CSRP1,CCND3,STX5,RAB11B,ARL6,CRYZ,FOXC2,PITPNA,RAB32,CRYBA4,BLVRA,FAM193B,APOBEC3B,MLH3,PCBP4,TULP3,HS3ST1,BMPR1B,OR4M1,SPDYE4,ADH1B,RANBP10,SRM,MED27,PSMD1,BARX2,MPP1,PTPRZ1,IFI16,SART3,MYLIP,FAM174A,SUPT4H1,VPS39,INA,CFTR,ATG3,CLPX,CLP1,OR5AN1,VWF,ATP6V1D,CDKN2D,ESD,GPR37,TMEM39A,ART5,PSMB10,CDK17,DIRAS3,TP53TG5,ATG16L1,SIGLEC5,HDAC11,TTLL10,CHCHD2,SKP1,CSF2,PCYT1B,PRELP,KRT8,GJB1,GCHFR,HNRNPH3,LCP1,AGGF1,ZNF200,TPST1,IZUMO2,RBM41,COPE,SLC25A3,RWDD1,PABPC5,HCFC2,DCTN3,LSM5,IRF2BPL,PRKCB,RGL1,SUV39H1,RPL4,SEC14L5,SPAG11B,HBP1,CKS1B,DYNLRB2,AQP3,RIMKLB,PRELID1,ETFA,CD59,ECD,APEX1,PRSS1,PSMC5,ITPRIPL2,JMJD8,GAB1,AKT2,KCNG3,CHST10,SOX9,OR2D3,PNPO,COTL1,GPM6A,HS3ST3A1,TICAM1,TLR5,RFC4,LCN1,DCAF16,CLRN2,DNM2,OR4K13,C1QL2,PLCXD3,REG1A,MMP20,GTF3C4,SMARCB1,HTR2A,ACTR1B,STAP1,STARD5,FMO1,ABCC2,SUGP1,ALG5,DEXI,SCN2B,ANKRD10,TEF,TMEM231,PCP2,TCTA,SOD2,ADD2,KLF12,MLN,WDR12,RAB1A,GLO1,PDCD1LG2,NEU1,VSTM4,AMELX,PIGK,PELI1,CNOT8,MAP1B,ZDHHC17,FBXO31,RACGAP1,CORO1C,RBM3,CCDC126,RRP7A,STT3A,MAGEA4,PIK3CG,RPSA,NPBWR1,UBE2S,HYAL2,ERLIN2,ARHGAP15,RHOH,TMEM126A,SETD3,GPR75,ACP2,GNPAT,FOSL2,ACTL6A,STARD7,DIO2,EGR1,ZNF436,WBP11,ZNF343,SYPL1,CHTOP,TBC1D1,GPR34,XBP1,RPF2,TIMM13,GABBR1,ERCC3,THG1L,PDLIM4,TACR1,ARHGAP19,CEP57L1,OSBPL8,CA14,DIS3L,CEACAM5,NAP1L3,DRD3,MTA3,EMILIN3,CHRM5,NACC2,SEMA7A,NAP1L5,APOC2,CYB5B,ZCRB1,MED4,BCKDK,OR9I1,TRMT5,HPCAL1,MRGPRX1,CAMKV,ARL5B,F2,ESYT1,ANKH,VPS26B,YKT6,AANAT,EDC3,HAPLN2,SAP30BP,WNT2,GMDS,TRAPPC3,NRGN,CSRNP3,LDB1,BIRC5,SNN,SNRPA1,CEP70,ABHD2,ARL6IP5,CTDSPL2,DTL,NDFIP1,KDM1A,CCDC22,TBCEL,UNC45A,FKBP2,PRSS35,ISG20,TMEM87A,RALB,NUDT1,GMNN,CYP26A1,SNX11,RPLP1,SERPINB9,MT1X,UBE2V1,TIMMDC1,IMP4,TRNP1,HELT,PDE6A,EMX2,SEC61G,CENPM,SSH3,HOXB8,GFM1,ADIPOR1,PRM1,GAL3ST4,MET,FZD6,RETSAT,POPDC3,SLC7A11,RANBP1,CTLA4,RBM5,ATF3,MAP1LC3B,PRSS37,PDLIM3,IFRD1,DEFB1,ACSS2,RHOU,B3GALT4,DLG3,CEBPE,RPL22,TMEM176B,CD200,TMEM168,ST8SIA4,TMEM220,NCK1,STRADB,LRP3,SIAH1,AHSA1,ZBTB6,PLEKHF1,SLC15A1,KCTD16,GPR78,HNRNPAB,TRIM62,ZNF655,TEX19,CDKN1B,CMBL,COX7B2,SCHIP1,HMGN4,MEA1,TAF9,SCG5,PHOSPHO2,MAT2A,NMRAL1,RFX5,TMEM198,TRAPPC2L,OR6C4,LRRN4CL,GDAP1L1,PDCD10,SSBP2,WTAP,RPL31,MGST3,TSPAN3,BAD,OLA1,PRPS1,HAS3,AKR1E2,CRHR1,NOC4L,UQCRC1,SERPINA3,KCTD20,RASSF4,CLK1,SKAP2,RSL24D1,TRAF1,BRS3,ZMAT3,NAA30,C9orf72,CDR2,PTGER2,NETO1,DDX39B,CGRRF1,LSM4,IRF9,HSD17B8,DOK6,SEMA3C,PSMB4,HERC3 |
| 7.558e-13 | -27.91 | SFPQ (splicing factor proline and glutamine rich) | protein interactions | 6421 | 515 | 219 | 19454 | 5460 |
MIR155,KRAS,CBLL1,LSM14A,TOP2B,MIR9-2,MIR206,EWSR1,MIR222,MIR9-1,SNRPA1,FAM98A,HNRNPL,PEG10,SIN3A,MIR214,MTHFS,EED,AGR2,MIR31,MIR140,ANKRD50,MIR221,WWP2,MIR143,IFI16,CTNNB1,DDRGK1,MIR29C,EEF1G,STAU1,UFL1,FXR2,SNRPA,EP300,DDX5,SF3B1,HSPA8,HDAC5,CTBP1,NCOA5,PIH1D1,NUFIP2,TIMM10,MATR3,APEX1,SF3B4,PRMT5,MIRLET7B,ZMYM2,RBM27,SFN,HNRNPC,MYC,BTF3,MIR16-2,MEPCE,MIRLET7C,MIR200A,IDH1,MIR9-3,DHX9,RAB13,DDX42,NUPR1,RNF8,TP53,WBP11,MIRLET7G,RPS16,FZR1,CDC5L,MIR429,ALYREF,CD274,SYNCRIP,SNRNP70,NR4A2,COX5A,PPIL4,CSNK2A1,CD81,COPS5,MIR29A,HSPA5,MIR107,PML,ORC6,MIR10B,BAP1,RNF113A,PGK1,RPA2,TRIM68,MIR7-1,HECTD1,STAT6,HEXIM1,UBE2M,TFIP11,MIR21,MIR34B,CFTR,IGFBP3,DYRK1A,PPP1R10,PSPC1,UQCRC2,SPOP,UBE2H,RBM7,CARS1,SMARCA5,TRIM37,TNF,RAD21,UBE2A,SRSF4,HNRNPA2B1,SRSF7,FAM76B,CHMP4C,EZH2,TMEM14B,DPH5,ZNF263,NUP35,PPIA,MIR7-2,PHB1,MIR141,TSG101,DDX23,HNRNPD,AHSA1,MIR1-1,NDC80,PRPF19,PIK3R1,HNRNPA1,ASB3,MIR106A,PSMA3,CRY1,PPARG,PRRC2A,MIRLET7D,SNRPD2,AP2M1,BRCA1,RIT1,SP1,MIR363,CUL3,MIR98,JPT1,TOMM40,VRK1,THRAP3,HUWE1,MDC1,SMN1,RIGI,RPL23A,NDUFS3,MIR17,MIR20A,TOPORS,YTHDF2,FBP1,EXOSC8,EEF1A1,MIR200C,CD2BP2,MIR15A,TOP1,CWC15,MDM2,CDK9,PTP4A3,MIR106B,MIR25,MIR34A,NFKB1,MOV10,HDAC6,FBXW7,MIR7-3,PIAS1,MIR205,SIRT7,RPA3,MIR34C,MIRLET7I,CZIB,MMADHC,METTL14,SLC12A2,LMNA,SF3A1,CDK7,MIR1-2,NDN,TXN,VIRMA,SMAD5,UBB,CTTN,CCNF,MIR16-1,UBE2I,ACAT1,MIR145,DNAJC19,DHPS,USP14,AR,NONO,RUNX1 |
| 7.874e-13 | -27.87 | organic substance biosynthetic process | biological process | GO:1901576 | 4177 | 1416 | 18204 | 5365 |
SNAPC5,AR,SOD1,MRPL52,IL2,CYTL1,HIRA,PAIP2,PFDN4,TERC,DOLK,PNPO,XBP1,RPL27,RPL13A,DIO2,PARL,SMU1,DCK,GLCE,ATP5MC1,B3GALT2,SRFBP1,PCSK9,B4GALT1,TAF11,RPL4,PIP5K1A,CKB,FKRP,LBR,CCT7,PDRG1,RPL26,FUBP3,RPS4X,HACD4,BMP1,CEBPE,B4GAT1,PRPS1,BAK1,VDR,SIRT7,CYB5R3,RAMAC,B3GALNT1,MDH1,DNAJB6,AQP11,HM13,MTAP,HDAC3,ATG7,PRKAG1,TUFM,NUS1,SLC35C1,PNPLA8,RPL7A,WNT10B,PAX6,RIGI,URM1,GFPT1,DUS4L,TENT4A,CLIP3,RPL12,GNPNAT1,RCL1,FOXP3,AGPAT5,PADI2,DDX39B,CDIPT,NDST1,UTP6,EIF4E,MMP14,ABHD4,THOC6,POP5,IMMP2L,POLD4,CYP21A2,VPS54,TRMT10B,RPL7L1,DPP4,PRPF31,TBCEL,G6PD,MRPS25,APOBEC3A,C1D,DNAJC1,RBM42,KIN,EIF5B,GLRX5,GCFC2,RPL10A,NPPC,SELENOT,ZC3H11A,APOBEC3C,PPIC,ZDHHC17,EAF2,TESC,PCYT1B,HNRNPL,MAK16,SYK,FA2H,CNOT6L,MED23,MED9,TRMT112,GPAM,RBM17,CERS2,VSIR,APEH,PTDSS1,STT3A,CDC40,NDUFB8,CAPN2,DEK,HS2ST1,ELOVL4,CTNNBL1,ST3GAL5,PIK3R2,AGK,GTF3C4,MGST3,SAMHD1,PPM1B,RRM1,EIF3E,RPS11,UNC45A,HSD17B8,CD40LG,RBM41,RPL35A,BACE1,UTP25,CHTOP,CYP39A1,RPS10,SUPT4H1,THOC1,GFM2,APEX1,CHST13,F7,TAF10,ATP5PB,PIK3CA,NMRK1,ELOVL3,RBM23,DNAJC25,MVD,CYP1A1,LSM8,MTRF1,QTRT2,IMP4,CWC15,SART3,SOX9,ERO1A,BAG3,PPIG,CSNK2A1,CPEB1,HNRNPA0,AZIN1,CPSF4,DHRS7B,DRG1,HSPA14,DNPH1,PRPF19,PELO,DHX15,CDC5L,EIF4EBP2,FKBP1A,XXYLT1,ZNHIT6,SRSF7,DDX4,ADRB2,PRDM4,HAND2,MAT2A,RNF8,STAT6,SF3A1,THOC3,RPP25L,FKBP2,CHRAC1,DBR1,LSM2,RPRD1B,SMNDC1,LTO1,AANAT,SUGP1,PAOX,ST6GALNAC3,GFM1,CHST9,DGCR8,RPL37A,FAM98A,FXN,ATP5PO,NDUFC2,GTF2H4,CDC37L1,PAAF1,THAP1,RUVBL2,YAE1,CMA1,SWAP70,RPL17,F9,MOXD1,GPBP1L1,TRMO,UST,PCSK2,EIF5A2,REN,NXT1,MIF,NDUFS8,SOCS2,SECISBP2L,AGO1,CRYAB,MTMR6,HACD2,RPS14,DDX42,TLR3,SREK1IP1,CHST7,FUT8,ABCF1,NHEJ1,CASC3,BOLA3,NLRP3,PDHA1,H2AB1,RP2,FDFT1,CD2BP2,GGT7,TAFAZZIN,RPL6,CASP4,MED4,LSM3,SUPT5H,GTF2A2,CCT8,PCLAF,RPL28,CERK,RSL24D1,PLAC8,STUB1,DNAJC10,PHB1,TEX12,PPT1,CYP17A1,RBM3,RBM15B,TRMT61A,FYTTD1,SLC25A12,NAA35,DDX46,B4GALT3,TRA2A,DROSHA,HEXB,FAR2,ZNF326,PIWIL1,CYP27B1,WDR6,METAP2,LGALS3,CDC123,MRPS11,USP39,RARS1,SORD,RBMX2,ST3GAL4,HSPA8,PPIB,BAG2,SCD5,INTS10,ZNF473,RPL9,ZNHIT3,RPL35,DDX5,NCBP2,SLC25A39,SPCS3,TP53,FADS2,TRMT13,HENMT1,UBIAD1,GYS1,ATG4C,TRIM24,RIC3,CDK12,GAMT,B4GALT7,BAD,SPTSSA,ADCY2,EIF3G,KPNA6,AKR1A1,TSPAN15,CHPF,GRB10,ISG20,MRPS34,PRMT5,GON7,MRPS35,AKAP17A,DPH3,TMEM106A,SLC1A2,NPR2,RPF1,CRTAP,NPC1L1,HSD17B10,RPN1,WDR77,CRYL1,CSTF3,PIK3R3,RFC3,UQCC3,EP300,GEMIN8,RBFOX3,MRPL22,INHA,METTL2A,ENPEP,TIA1,RWDD1,ESS2,H3C1,RMND1,RPLP0,RPL26L1,MPHOSPH10,POLR3F,SNAPIN,EIF4E3,ELK1,SNAPC3,LYAR,SLC1A3,OSGEPL1,UPRT,IMPA2,LUC7L3,MRPL11,THUMPD1,MRPS7,HSPD1,PNP,MAT2B,RNF14,SNRPB2,POLR3B,DUOXA2,STOML2,ASMT,TMEM59,ACAT1,TXNL4A,SELENOI,CHKB,THBD,NUDT12,GSTM4,TTC1,MGAT4A,P3H1,LIPT2,SUPT3H,PLP1,KCNJ8,THTPA,NFKB1,ARG2,B3GNT2,HINT2,MRPL18,CYP2C9,RPAP2,HNRNPF,PRSS12,FOS,PRSS37,CLPX,TYW3,GFUS,ELP3,DNAJC4,NDUFA5,AKR1B1,ATF3,SNRNP27,WDR83,ZDHHC4,PPAT,SELENOK,NXT2,EIF4A3,TAF9,SNRPN,HNRNPD,GPAA1,TRMT1L,SMAD3,CMTR1,ATG16L1,METTL14,NBN,HS3ST3A1,CCT5,TFIP11,ASNSD1,RPS24,IFI16,TLCD3B,PGK1,MAN1A2,TMEM208,UTP15,C1GALT1C1,PIGK,SLC30A5,IRF1,PQBP1,DNAJC5,KRR1,EXOSC3,CELF6,MRPL50,ADGRG1,BMPR2,MECP2,B4GALT4,UBL5,HNRNPK,SF3B6,ATF4,MGAT4B,POLR2F,NOVA1,ATP5MC3,CHPF2,METTL6,ISCA2,PSEN2,CHDH,ANGPT1,PPID,SRC,PPIL3,MTMR2,NRDE2,SRGN,GXYLT2,EXT1,PTGES3,DHX38,MEF2A,MRPL53,OAZ3,PRKRA,PGM1,RBM27,FAU,GPR37,PGRMC1,RPL8,DTL,ZRANB2,TENT2,MRPL36,CISD1,CDK7,ETNK2,NDUFA2,HYCC2,CWF19L1,TECR,PRCP,GPX4,SNRPE,SNRPA1,WDR3,AHSA1,MACROH2A1,ERG28,PFDN2,PIWIL2,RP9,PDHB,RTCB,FARSA,NPM3,QNG1,TTC4,PXYLP1,FMO1,EIF3J,NFKBIB,GAL3ST1,NDUFA1,TCEANC2,PCNA,ATP5F1B,SNAPC1,METAP1,TGFB2,DTWD1,SLC6A3,SNRPD3,POLB,PLSCR3,SRPK2,RPS27L,ARB2A,EGR2,PLPP6,WBP11,POLR2I,YBEY,SNRPA,TAF2,ZCRB1,ZMPSTE24,SMPD2,CD28,HSP90AB1,CBFB,FKBP1B,MRPS33,SMG5,FCF1,PFDN6,ATP6V1A,DAD1,WDR45,HSP90AA1,USP15,EIF2S2,SOCS4,NDUFA12,POLR3GL,OST4,INPP5K,TDRD7,PTGES,SCNM1,G6PC3,HSPB2,SLU7,CREB1,SELENOF,WWP2,HNRNPA1,PMPCA,THOC2,MRPL16,DNAJC30,SPON1,DNAJC19,ACOT8,RPS28,BOLA2B,LDB1,RPS16,SCN2B,KTI12,DIS3L,MTRES1,CFTR,OGG1,ANKH,QRSL1,SPCS1,PPAN,SPHK2,RPF2,PRPF4,DPAGT1,BATF,BRIX1,S100A10,PIR,HMBS,MME,RPS29,RPS3,EEF2,ETF1,ADIPOQ,PLAAT3,GALNT2,TAMM41,RPL23,CCNA2,LIPA,CYP7A1,NSDHL,GLE1,TSPO,GNPDA1,KDSR,MRPL47,AASDHPPT,AK3,ATP5F1E,SLC25A11,PYCR1,RPS5,EDEM3,MYRF,GNPDA2,POLR2L,LSM6,CLN8,FKBP10,MRPS18A,TSEN54,SEC11A,UGDH,NONO,POLR1B,GGTA1,ACSS2,PIWIL4,NDUFAB1,HELT,ATXN1L,MTHFD2L,FGFR1,ZMAT5,PEDS1,VPS72,SPPL3,IDO1,TAF7,PFDN1,MSH6,EIF4A2,CPE,COQ8A,TSPAN5,RPRD1A,ACER3,DOHH,SLC25A10,PLA2G5,FTSJ3,NR1H2,PPP5C,EIF4B,SLAMF9,DNAJC24,UBA52,EXOSC8,METTL15,MTERF2,IL1B,AKT1,CLP1,ELAVL4,KBTBD2,ATP5PD,INPP5E,GSTP1,NUDCD3,SKIC8,CALR,CHCHD1,GRSF1,MRPL23,SGMS1,ENY2,WTAP,DKC1,IGF1,APH1A,ST3GAL2,DNAJC3,B3GALT4,SRD5A3,CDC73,DNAJB2,LPCAT3,RBM34,OCRL,DHX16,RPL10,MGST2,ORMDL1,NCAPG2,GTF2A1,MED27,TAPBP,PIGW,EXOSC1,ACP6,EDNRA,RPL27A,PAPOLA,ADSS2,MAD2L2,GMDS,SMN1,SF3B4,FUT1,ERRFI1,DHPS,DLAT,SLC37A4,COPS2,GGPS1,RPLP2,HS3ST5,AKT2,DEGS1,NOP58,SEPHS2,ADAT1,LSM5,PAIP1,ACAA2,AGPAT1,IL6,HEXA,TRAF3IP2,GP9,DDX1,ZDHHC14,POLR2C,ACSL4,FBP2,CHAC2,CYP27A1,NKX3-2,DNTT,PPIF,TRMT6,MECR,AKAP8L,YIPF5,FKBP4,ST8SIA5,RPS13,MRPL13,CCNH,GTDC1,MRPS9,MRPL12,SGMS2,HSD17B3,PIGA,PIH1D1,RDH10,ATP5F1D,EXTL2,WBP2,HPGDS,UCK1,POLR2B,MRTO4,DHRS11,MGAT5B,CCAR2,MED22,MRPL17,SGF29,NOL7,INTS12,DPM2,NME2,FOXA3,POLDIP2,ARFGEF1,NOC4L,MED10,SCG5,MSMO1,GK2,CH25H,STAR,MRM2,NPC2,PRKAB1,MRPS18C,GLUL,TCEA1,XPO1,UCKL1,LHB,MCAT,TRUB1,MRPL49,AK5,PIGY,NIBAN2,SLC52A3,TCP1,CPSF2,NDUFS6,CUL3,PIK3R1,CCDC47,CMPK1,HMGCS1,RPL31,BCL9,RCE1,FABP5,GTPBP2,MRPL41,NDUFB4,ABHD2,GTF2E1,HSPB6,RPS12,INSIG2,PIK3CG,VAC14,HNRNPA2B1,TRMT11,ABCG2,COX11,TOR2A,WRAP53,NDUFB10,GTF2H2,CHST1,MAGOHB,GNPAT,WDR55,SERINC1,DECR2,ADRM1,NUP107,RBMS2,FIG4,GMPS,ADK,NDUFS2,WDR12,CHST11,SF3B5,POLA2,DICER1,GXYLT1,TOPORS,BECN1,ALG11,MRPS17,PDF,EXOSC4,RGN,RPL7,SUB1,IL1R2,NSA2,CTU1,SLC19A3,CCS,GAD2,BUD23,TSN,NHP2,ZNF345,CCR6,UAP1,GALNT4,PLA2G15,SDF2L1,DHX9,AMACR,SEPHS1,COL3A1,PGAP2,EIF2B3,LIAS,HYCC1,RPL29,LTB,ZMAT2,TRMT5,ATP5MG,OSBP,GTF2B,CYP4F22,RPL10L,MRPL57,LSM10,TAF5L,MYD88,SOCS5,HSPA5,HTRA2,KLHL3,MRPS16,RPS9,AK2,RPL18,SNRNP48,FURIN,ALG5,FASTKD5,THG1L,EEF1E1,OSGEP,SRSF12,TSSC4,NDUFB7,BARX2,GTF2F2,PMM2,ATP5F1A,PGAP3,PPIA,ARMC7,RTRAF,IFT172,RCHY1,SAT1,PELP1,GBE1,MMUT,SPR,TUSC3,ZDHHC15,MFAP1,SDHB,ALDH1A3,RBM38,CNTN1,SNRPD1,CEBPG,GTF3C3,GALNT12,CHST2,IK,CITED1,ELOVL1,PTPMT1,RB1,RSRC1,TYMS,CYP11B1,PRPF18,DCTD,RBM5,CDK9,NFYA,FBP1,FITM1,ABHD5,HINFP,MRPL34,OAZ2,MED11,ATP5MK,BCKDK,PFDN5,BCL6,SSU72,ORMDL3,PDE12,PDIA3,SF3B1,GRPEL2,TNF,SHMT1,CYP11B2,GMPPB,SC5D,RPL15,PAPSS2,MLF1,MRPL10,GSTA1,SUV39H1,CDO1,BPNT2,PPWD1,ALG2,SNRNP40,TCEA2,GTF2I,PRIM2,EIF2B2,B2M,CYB5R1,GPHN,RPS26,GAPT,HMCES,IMP3,TLR4,RPS15,TMEM165,POLR1H,TOR1B,IP6K1,INPP4A,SPTSSB,B3GALT1,KLF4,LARGE1,SAP18,EMG1,TRIP4,TMEM38B,CHORDC1,ITGAV,GEMIN7,ZC3H7A,FTSJ1,CSGALNACT1,OAZ1,LEPR,NDUFV2,EPOP,MAEL,ST6GAL1,CIAO1,ACCS,PIGC,DDX23,CYP2C8,RRN3,ATP5IF1,MRPS18B,POLL,EIF2AK2,RIOK2,TUBA1A,ABCE1,ACACA,UGCG,CRY1,POLR1D,INTS6L,GALNT17,TSR2,PTEN,JAK2,MED31,DDX39A,SMAD4,RPS27A,LSM4,PDIA2,NOP53,PYCR2,CYFIP2,TSNAX,SHLD1,SLC1A1,CTNNB1,CYP2R1,KARS1,GK5,POP7,COQ10B,PRKD3,EIF3D,NAA16,MAGOH,DR1,CERS6,RPSA,EEF1G,RPS2,ECD,ELP6,WDR82,PHKG1,GUK1,CREBL2,HACD3,PRPSAP1,SYNCRIP,NGDN,PCK2,NDUFS3,IREB2,RPLP1,SRSF10,HYPK,LIG3,BAP1,ELOVL7,DCAKD,KHDC4,MED29,RPS23,ADCY3,PC,HSPA13,UCK2,RPL39,ST13,PPARA,EEF1A1,GAL3ST4,TRPC1,ENO1,AURKAIP1,HAS3,VIRMA,GTF2F1,NDUFB6,NANP,ERP29,RNASEL,RPS17,THRAP3,UMPS,GRM2,UTP23,NDP,DNLZ,FKTN,CSGALNACT2,NAA11,ZDHHC16,MRPL24,TSR3,DNAJC7,FAM20B,CD2AP,FMO3,MRPL20,ALOX5AP,MRPL33,PABPC1,TERT,GTF2E2,HS3ST1,EIF2S1,FUT9,RPL24,NDUFB5,SNRPD2,CBR4,SLC11A2,UGP2,RPL32,TFCP2,BMPR1B,GRPEL1,HSD17B6,PKNOX1,RPS7,RPL3,MED30,SDS,CISH,RPL19,CLU,ELOC,POLD2,CRTC2,EIF1AX,ATG4A,PCBD1,EIF2B5,PGS1,RPP25,EIF1AD,EIF3K,MGAT1,CCDC3,SNAPC2,DTWD2,ALYREF,GTF2IRD1,SRSF4,PDIA6,SLC38A1,DRAP1,NOB1,IVNS1ABP,SMARCB1,HACD1,GOLGA7,SACM1L,GCNT3,DNAJB4,PTS,SQSTM1,LEP,POLR2G,SNRPB,MRPL51,TCOF1,PIWIL3,SERPINH1,EIF1B,SMARCA5,SDR42E1,NME1,PDSS2,CSTF2T,CPSF1,ELOF1,MED17,GALNT1,SERINC3,HSPE1,ATP5PF,AIP,MRPL9,MTF1,HNRNPC,METTL25B,COPS5,FOSL2,ILVBL,COIL,SMAD1,CCT2,ZDHHC24,PROX1,CREBBP,RPL22,MPDU1,EIF2D,GSTM2,PGAM1,GCLC,IL2RG,DRG2,RPP21,NUDT2,TWNK,MRPL40,GTF2H5,PPP1R3C,DPY30,SAT2,KRAS,MRPS21,MTM1,PSEN1,RNF113A,DTYMK,SLC19A2,SNRNP70,SNRPG,MRPS23,APOBEC3F,BUD31,ALKBH5,BRCA1,SMAD2,MPHOSPH6,IRF9,CYP2D6,RBM22,POLR3H,RPP14,ST3GAL1,NME4,NAA60,ODC1,CDKN2D,MTG1,NDST3,RBFOX2,PRDX4,SOCS3,COQ8B,PWP2,NAA50,NFIL3,MED21,ATP6AP2,POLR2D,SNIP1,SRM,OAT,DDT,ISYNA1,SLC25A1,MARS1,HSPB1,ACTMAP,RPL23A,TYW5,MRPS26,FITM2,MRPS28,TPH2,HSD17B1,PLSCR1,PPIH,PIP4K2C,POMT2,EIF4E2,AZIN2,WDR83OS,MTHFS,LMAN1,TFB1M,GUCY1B1,TRA2B,NFE2L1,HSP90B1,ELOVL6,EEF1B2,FRA10AC1,TSEN34,INPPL1,CD226,CARS1,PYCARD,GTPBP1,HNRNPH3,H2BC1,KLK6,ZDHHC8,DFFA,PPP1R1B,DBH,MSX1,SRSF8,SRSF2,NAA15,ZC3H15,POLDIP3,B4GALT6,POLE4,PPARG,ST8SIA4,GOLGA7B,FAXDC2,HDHD5,SLA2,SPCS2,SDHC,NCSTN,EIF4H,RPS20,MKKS,IKBKB,CHCHD4,EGR1,PTGDS,EPO,MNAT1,NR4A2,DDIT3,DNAJC2,ENO2,POLE3,RRP7A,COMT,PSENEN,TBCE,CMTR2,SRSF1,PGAP4,COX10,NOP9,FKBP8,ERCC3,ABCC5,HSD17B11,CHST10 |
| 8.087e-13 | -27.84 | ORF10 (ORF10 protein) | protein interactions | 43740576 | 547 | 230 | 19454 | 5460 |
NCBP2,TOMM70,TOP1,THOC1,CHID1,TES,MYBL2,TIMM8B,PTPN1,NME2,POR,GLO1,MOV10,CALR,MDC1,PRDX4,EIF3E,PTGES3,ARF4,CTNND1,FASTKD5,HSPE1,FARSA,ERLEC1,HUWE1,EMC2,SFXN1,NDUFS3,ACTR2,HSPA13,MAP1LC3B,NDUFA2,YTHDF2,CMPK1,CCDC47,SEC63,TMOD3,PNP,LDHA,GANAB,RTRAF,EIF4A3,SELENOT,MAPRE1,NAPA,ARFGAP3,TUFM,CTSD,MBD3,YKT6,SQSTM1,TCEA1,MAVS,IDH3A,HNRNPH3,NOL7,HSP90B1,GOLGA5,CHMP1A,LMNA,P3H1,EEF1E1,SEC22B,OS9,ERLIN1,SPTAN1,MRTO4,AHSA1,HNRNPA1,SAV1,STOML2,PDIA3,TMED7,ETFA,BAG2,ERP29,SRSF7,PCNA,NUDT5,PPID,RPN1,ERLIN2,FAF2,ACTN4,YIPF3,MARCKSL1,ABHD12,ACTB,AP2M1,POLR3B,CYB5R3,PIGK,FAU,PFDN6,SCFD1,LMNB1,MYO6,MCM3,MRPL16,RNF40,CUL2,RAB11A,STX7,ATAD1,RADX,YTHDF1,TTC1,DNAJC3,NDUFA5,FAM3C,HEXB,FKBP10,VAPB,PRDX3,PGRMC1,CDC5L,LMAN1,ILVBL,FUNDC2,RPS27L,ARL6IP5,CAND1,DSTN,STT3A,SDHB,SYNCRIP,USP15,TPM3,GAPDH,ELOC,RIT2,KARS1,CSE1L,ERO1A,SLC25A11,ARPC3,TFRC,SURF4,RPSA,TP53,RAP1A,BCCIP,CDC20,TXNDC12,RALA,SEC61A1,EIF2S2,PSMC5,ZBTB33,UQCRC2,SORD,CALU,CCDC174,DTL,OAT,DNAJC5,GORASP2,CFL2,CFL1,RAB2A,NDUFAF2,BNIP3L,HSPA5,GRPEL1,AIF1L,DLAT,GFM1,PRDX6,RAB29,LEMD3,SAMM50,SSR1,GALNT1,SDCBP,H2BC11,SPTBN1,NOB1,EIF2S1,PEX13,RPS10,CORO1C,SRSF1,RAB35,DDX1,YWHAH,PPIB,RAB5C,POLDIP3,RAB18,VDAC1,RTCB,PDIA6,SCPEP1,DCUN1D5,PDHA1,PLS3,NCSTN,CCDC134,HEXA,ETFB,MIEF1,POLR2B,CBX5,DLST,VDAC2,SERPINH1,THTPA,ZMPSTE24,CHTOP,SPCS3,CPSF2,LDHB,STAU1,PHB2,EMC1,UFL1,FXR2,TRA2B,AKAP1,HSPA8,TAPBP,PYM1,NUFIP2,PPT1,CTBP1,EDEM3,MRPL12,CNPY3,GPC4,TOMM22 |
| 8.296e-13 | -27.82 | ERAL1 (Era like 12S mitochondrial rRNA chaperone 1) | protein interactions | 26284 | 234 | 117 | 19454 | 5460 |
MIR200A,MIR9-3,MRPS18B,TGFBR2,MIR16-2,FASTKD5,MIRLET7C,MEPCE,MRPS18C,MRPL11,EXOSC8,METTL15,APOBEC3D,MIR15A,AURKAIP1,MIR20A,MIR17,GFM2,ALYREF,COX4I1,SSBP1,MIR106B,AIFM1,MRPS9,PRR3,FZR1,CAND1,MRPS23,CDC5L,SLC25A46,GRSF1,SNRNP70,CHCHD1,SSX2IP,MAIP1,SQSTM1,GFM1,MIRLET7I,MIR7-3,FBXW7,COL3A1,MIR107,MIR34B,COQ8B,RBMS2,MRPS34,MTRES1,MIR21,ZNF574,HEXIM1,MIR16-1,CCNF,RHOJ,FOXA3,TUFM,MIR145,MRPS16,SPOP,COL1A2,MIR9-2,NDUFA4,HSPD1,COX8A,SRSF7,MRPS11,HINT2,MIR206,MIR155,KRAS,IMMP2L,HNRNPDL,MRPS17,SRSF4,RAF1,SOX2,PDHA1,FBXO32,PHB1,MIR7-2,FAHD1,GATD3,MIR214,MIR141,RHOH,MIR9-1,RMND1,COX14,MRPS35,MTRF1,RHOG,MRPS26,MIR221,MIR1-1,EXD2,FAM50B,HSCB,MRPS7,MIR106A,NT5C3A,DUSP14,TSHR,FOXS1,CCDC90B,TACO1,MIRLET7B,RPL10,PARL,ESR2,MIRLET7D,PMPCA,CUL3,MYC,MTG2,AUH,NOA1,MRPS25,MCAT |
| 8.524e-13 | -27.79 | positive regulation of signaling | biological process | GO:0023056 | 1794 | 661 | 18204 | 5365 |
FAF1,RPS20,OSBPL8,MIR198,CHRNA7,EZH2,IL7,ATAT1,TPBG,EPO,S100B,HINT1,C1QTNF1,TRIM44,SIAH1,TRIM15,CYP27B1,GAPDH,IL34,IKBKB,TGFB1I1,RBCK1,PPARG,CLSTN3,MIR212,LIPA,RPL23,SFRP4,F10,SRARP,CSNK1A1,CCDC22,PDE9A,F11R,TRIM52,KLHL22,ZNHIT1,IRAK4,TNFAIP8L3,JUP,RELL2,GPNMB,PPP2R1A,SESN2,AVPI1,MAP3K3,CLEC7A,MIR1-1,NEK7,DDX5,TNFSF10,LPAR1,RRAGA,SDCBP,TP53,SPPL3,CTSC,FKBP8,STK4,PIP4P1,CRBN,PTPN11,NETO1,HOMER1,ZBED3,RPS15,TLR4,DLG4,DDIT3,LRRC8A,PRDX2,MIR26B,P2RY1,FGFR1,TMEM33,GABBR1,ACKR3,ITGAV,LARGE1,FGF22,PTPN1,LAMB2,GHR,ADORA1,FBXW11,CASP4,ILK,ADNP,CITED1,NPY5R,GPR89A,LGI1,LSM14A,RELL1,VAMP2,ZNF622,SPHK2,TIFA,CCR2,F2,CTSD,CSNK2B,DDR1,CFTR,GJA1,PRKCA,ACVR1,NLRP3,MSX1,CX3CR1,TRAF2,MIR145,SEC13,AVPR1B,TESPA1,PHB1,EDA2R,LY96,TRIM6,RPS3,PDIA3,RUVBL1,LRRTM2,VAMP7,ADIPOQ,TNF,CRLF3,FGF17,TWSG1,FGF3,MAP3K11,ROCK2,IL10,MUL1,RBPJ,CX3CL1,SLC39A10,RAF1,CXCR4,TBC1D24,TMEM198,PLEKHF1,CD226,AGER,LURAP1,HRAS,PYCARD,MIR23A,MME,CXXC5,MAPRE2,FGF7,HMGB1,PTK7,STX1A,KLK6,HFE,MYORG,HSP90AB1,CD28,PIM2,ING2,STAMBPL1,CDKN2AIP,GPR35,LANCL2,MEF2C,IFNB1,CAV1,EEF1E1,DOK4,SLC20A1,TMEM101,USP8,RC3H2,CSNK1G3,DEPDC1B,MAVS,GPBAR1,TAB1,TNKS,IGFBP3,FAM83B,MIR324,PSEN1,MIR146A,TNKS2,ARL6IP5,CD81,CD4,TRIM26,ATP2C1,HBEGF,GFI1,HTRA2,NPTN,IL4,GADD45B,TACR1,MYD88,MIR421,MIR342,SMAD2,SFRP1,FLCN,MIR126,CREB1,IGF1R,MYC,CSNK1E,FERMT2,IFT172,NUPR1,DUSP19,CDC42,PPIA,GPR17,CCL5,DOK6,TRIM68,TLR3,SOS2,AKAP12,RIMS3,MAP3K12,IRF3,USP15,IL6ST,SNAP25,STK3,OPRM1,MIF,CCL3,RASL10B,RWDD3,ATP6AP2,TPD52L1,TEDC2,DDT,HTR2A,BCL10,PRKCB,CCR1,MAP2K1,CHGA,SHC1,PAGR1,IGFBP4,RAP1B,NUCKS1,FKBP1A,NLRP6,IRF7,TLR7,MAD2L1,IL5,SLC38A9,DHX15,ING5,PELO,CAV2,RIT2,TMOD2,MIR1260B,ACTN4,LTBR,FIS1,BECN1,IFI35,ADAMTS20,LITAF,PICALM,MIR20A,GHRL,CCL21,PROK1,CSNK2A1,HCST,TRIM22,ANKRD6,SOX9,RHEB,CBL,NDFIP1,TNR,CTNNA1,RAB29,FGF10,LTB,GKAP1,NCK1,TRIM8,SPRED2,ACTA2,RIMS4,MIR346,MBD5,KRAS,NOTCH2,OSBP,IL1A,MAP2K3,TGFB2,CCR7,CDH13,SEMA5A,ADRB2,GREM1,RNF167,ENHO,MTDH,HAND2,CREBBP,PROX1,SOX2,PTPN22,COL3A1,PDE8A,GAS8,CA8,SPP1,VAMP8,DKK1,SEMA7A,VEGFA,BMPR2,IL23A,ADGRG1,PRRT1,MIR29A,LAMTOR2,TICAM1,RPS12,TLR1,AKR1C2,PPM1B,FABP5,SMARCB1,MECP2,NDC80,BMPR1A,FGF23,NTRK2,LMO3,NTRK3,MIR296,OPRK1,RXFP2,SHOC2,CUL3,ZNRF1,PIK3R1,NR2E1,AFAP1L2,OSM,TRIM3,PRKRA,NEO1,STAU1,RAB8B,ROCK1,PDCD4,PDCL,LYPD6,P2RY12,LGR4,MIR15A,PIK3CA,RNF146,DYNLL1,GPR37,F7,NLE1,PAFAH1B1,BIRC5,TAB2,DOK5,TCIM,NLGN1,SERINC3,ICAM1,SCHIP1,HEXIM1,PHB2,FASLG,LEP,SQSTM1,NECTIN2,MIR140,TRIM21,PIK3CG,CSH1,IL18,RB1CC1,LAMTOR3,TNFSF12,ANGPT1,SRC,ADRA1A,MIR16-1,CHRM3,NFKB1,CRADD,DRD1,PIH1D1,TERT,SRI,GNA11,IGSF11,HCLS1,CCL2,DISC1,CHI3L1,BMPR1B,NPPC,MAP2K6,NHERF1,NPSR1,TASL,WBP2,JMJD8,SYBU,NUP62,PML,VAMP3,CCL19,DIRAS1,C2CD2L,GRM2,NINJ1,TBK1,GSKIP,LAMTOR1,CD38,MIR181D,TICAM2,NDP,CYP1B1,MIR183,TLR2,TRAF6,GADD45A,NLGN2,TMEM108,RAP1A,PIK3AP1,CCN3,TRIM32,BIRC2,TFRC,LACRT,TRIM62,ALKAL1,DUSP22,CD63,MIR24-1,SMAD3,FCGR2B,RPS7,NOG,S100A8,PRR5L,HDAC6,ZDHHC17,FBXW7,NKX3-1,ATF3,RGL2,TRIM5,STAP1,CCAR2,SELENOT,ADIPOR1,STK11,SYK,FGF16,CD40,ACVR1B,RALB,CD80,CD36,MIR210,LPAR2,UCN,PMAIP1,GPR65,DSTYK,WNT10B,NMI,EDNRA,RRAGB,VAV2,TTC23,CLEC6A,MSX2,SEMA4C,CPNE1,NACC2,MIR519D,VWF,MIR30B,MIR21,FGFBP1,MIR96,CDC73,CACNG3,TNIK,INHA,RTN4,HDAC3,EMP2,ILDR1,PCK2,PLCB1,TLR9,GLIPR2,UBE2B,OCIAD2,MCL1,ELAPOR2,IL6,AGPAT1,NDST1,RSAD2,ERP29,TRAF3IP2,BAX,GADD45G,UBB,CD86,MMP9,BGLAP,PTP4A3,ASPM,LRRTM1,PEA15,ACSL4,TMEM100,DNAJC27,FOXP1,IL12B,UBE3A,DDX1,FGR,UBE2K,MIR449A,ADRB1,NEUROD2,MIR10A,GRM1,HAX1,BVES,TRAF7,DAPK3,OR2AT4,GPR37L1,SLC1A3,PELI1,FLOT1,GPR137,MIR186,TRIM34,PRL,MIR1224,AKT3,CA2,PRKCE,MIR545,GLCE,GSK3A,DVL2,RAMP3,CDK5RAP3,MIR10B,SLC4A8,G0S2,BAD,LIMS2,PTEN,PPP5C,JAK2,P2RY10,STXBP1,PPP3R2,TFG,NRP1,TIRAP,PLA2G5,BST2,FGF1,IRAK1BP1,TTI2,MIR221,PAK2,TGFBR2,MIRLET7B,ARRDC3,CRKL,SOD1,DIRAS2,CARTPT,UBE2N,AR,MIR320A,GRIA1,ADRB3,XBP1,TSPAN5,KIT,GNAI2,CD14,FAS,EIF2AK2,VDR,TXN,MIR95,BAK1,CTSK,HYAL2,GID8,CTNNB1,GH1,TNFAIP3,SLC1A1,CYFIP2,OXTR,RALA,GPX1,RETN,KLK5,MT3,TMEM106A,PDCD10,SPRED1,IGF1,CIBAR1,EP300,LPAR6,SNX5,BOK,CALR,NSG1,MIR675,TMED4,AGR2,TLR6,PRMT5,DRD3,PFKFB2,SMAD4,GRB10,RPL26,FAM53B,PPP3CA,WNT7A,UBE2V1,MIR182,TGFB3,IL1B,AKT1,MIOS |
| 8.668e-13 | -27.77 | RNF8 (ring finger protein 8) | protein interactions | 9025 | 333 | 154 | 19454 | 5460 |
EEF2,TUBA1A,RPL29,RNF126,PNMA2,TUBB4B,RUVBL2,PICK1,PCNA,TRIM21,EWSR1,PABPC1,ABCF1,RFC3,PRPS1,RPS4X,PIWIL1,VDAC1,TNF,G3BP1,CTNNB1,QPCTL,UBE2E2,PRDX1,HSPB1,HNRNPD,MGMT,LYZ,CASP12,HBA1,IKBKB,UBE2D1,CSTA,WDR82,S100A8,PBDC1,ANXA4,PHB1,PSMB4,FABP5,DNM2,LANCL1,RPL7,SPTAN1,SUMO2,SUMO3,EIF2S1,LMO4,PPP1CB,ACTL6A,SLC25A3,LCN1,SF3B1,HSPA8,XRCC5,RFC4,AZGP1,EEF1G,PHB2,UBE2D3,CCDC85B,RFC5,SCN3B,SFN,LDHB,MYC,THOC6,RIT1,POLD4,HSP90AA1,YWHAZ,RPS9,UBE2S,RPL19,GNB1,UBE2V2,MAD2L1,TUBB,TRIM29,RBBP4,ACTB,PRDX2,ATP5F1B,EIF4A2,USP16,GGCT,EEF1A1,H2AX,RPSA,CCT5,RNF8,JCHAIN,NDUFS3,SEPTIN7,MAP1B,MDC1,CAPZA1,OLA1,STX11,VRK1,HNRNPK,WASL,PSMA5,GAPDH,GPRASP2,MAP4,H2AC4,BCL10,PSMB1,UBE2N,EEF1B2,MDM2,THOC1,UBE2W,RBFOX2,SPTBN1,RPLP0,DYRK2,GSTP1,HSP90B1,SSR1,SNAI2,HBB,CDK1,JUP,LMNA,WRAP53,MTDH,NBN,HSPA5,POLDIP2,EIF5B,DGCR8,AR,NONO,ATP5F1A,PYCR2,CEP85,AKT1,CTSD,AP2A1,UBE2E3,ALB,CALML5,EIF2S2,ENO1,TUBA1B,PSMA6,RPS3,RPL22,LDHA,CTSB,BUB3,TXN |
| 8.804e-13 | -27.76 | large_intestine-rectum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-rectum-carcinoma-adenocarcinoma | 15834 | 4644 | 16828 | 4835 |
TFCP2,ABHD6,CLDN1,METTL2A,CTDSP1,CCNB1,FAM162A,NDUFAF4,CRYBB2,AKAP14,ERH,ALKBH5,ADIPOQ,ANKRA2,IK,LCP2,CRTAP,UHMK1,GNG2,EDEM1,METTL14,VAMP5,MBL2,MAP3K11,TOR2A,PTS,JPH4,AMIGO1,COL1A2,RMI2,SMU1,SLC35D1,CSGALNACT1,SAT1,SDF2L1,RUVBL1,CXCL3,GTF2B,NKIRAS1,OAS1,GIT2,CLDN4,LAMB2,SLC13A5,RAB3D,ZNF287,TMEM184B,KDM4B,ACAT1,TRIM54,ACBD7,FAM98A,CDC42SE2,RPLP2,TGIF2,GREM2,POPDC2,GPX6,HTR1F,OR4Q3,PDCD4,LDOC1,GPAM,PRPF19,CREBBP,RDH10,HTR5A,TMX3,EIF2B3,CHGA,GBE1,PAPSS2,TCF23,GPR65,SEC61B,TOM1,BCL7B,F9,PGPEP1,NKX3-1,GCNT3,OPRK1,MYO6,NDUFS8,CYP2C18,GPR137,BCS1L,SNX17,APOO,TMEM144,TOP1,SRRM5,NRSN2,DSTYK,CCR2,ZC3H7A,AIF1L,ZBTB5,TMEM123,CIDEB,ARMC7,ATAT1,IPO8,TMSB10,GPHN,ISG20L2,HSP90AB1,POLE4,SYP,ATG4A,ZNF862,CSRNP1,MRPS23,FUNDC2,RER1,FCN2,RGS7BP,CDKN2AIP,SFRP4,FUT9,PHYH,RTKN,NTN4,HOXD12,RPLP0,UBE2V2,IL10,RNF113A,EFNB1,THTPA,PREPL,SH3GLB1,TSPO2,OLFML3,GOLGA7B,ITGA6,CSNK1A1,PELP1,COMMD8,TFE3,IFNA10,MT1M,DEFB114,SNAPC3,BLOC1S2,SNCG,IGBP1,AKAP12,SSU72,DDX39A,RAB40AL,TMSB4X,TRIM5,EIF4E,LHFPL4,CALHM3,COX4I2,CDKN2C,SPECC1L,NAT2,KHDC1,RINT1,BZW2,OR10G9,TSPAN5,BCAP29,ZBTB17,FABP7,CD274,B3GALNT1,CREB3L4,EIF3K,EED,MRPS16,ABHD14B,YAF2,ELP3,TGFB3,MRFAP1L1,DTYMK,ACSL4,TRIM24,CIB2,MTRF1,ZNF592,EWSR1,GPX3,PROS1,TMEM204,EMP3,OSTM1,CHMP2A,VMP1,SLC19A2,CBR4,HSPA8,GMPPB,CALHM2,CCDC25,TES,BECN1,LMNB1,DNAJC3,RNASEH1,TMED7,KLK6,FKTN,SERINC3,SLC41A3,STAU1,TSN,STOML3,CDK4,NPR2,NR1I2,CNNM4,BRCA1,PCDHB1,ABHD4,RBM7,TRAF2,KCNK13,PDHA1,ADPRH,MBD5,NOS1AP,BCL10,KCNMA1,RGS2,STMN2,NME1,DUSP19,SLC32A1,FAM163B,PARP11,ZNF501,CEP97,IFRD2,ST3GAL5,POR,STK24,LCA5,RAC2,LRP6,TAS2R40,PYROXD2,MRPS21,CD36,IRF3,MTHFD2L,ERV3-1,KLC2,STXBP1,PAX9,STOX2,PRKAB1,UQCRH,DPEP1,DERL1,IL18,CSNK1A1L,SOX2,ST3GAL1,TAF5L,PNPLA8,MYEF2,UQCR11,GLT8D1,NGB,MOV10,PCGF3,GPX5,TCEAL7,GDE1,TMEM14A,OR14J1,CPSF2,CDH8,MRGPRX2,LRRC24,GRIA2,FLYWCH2,KLK5,LIX1,CAB39,DDX4,TMEM91,ZCCHC9,SLC43A2,TOP3B,TEX12,B3GNT2,HIGD2A,ACTL6B,FAM168A,LY6G5C,UBE2D1,SNIP1,SLC4A8,ZBTB45,ABHD13,HRH3,RAB1B,INHA,RPAP2,RGS5,OR5L1,RBMX2,NDE1,AMY2B,LDHAL6B,CCDC65,HMBS,TDRD7,CD2BP2,ELSPBP1,ORAI3,STX18,SLITRK2,RBFOX2,FOXN2,CDKN1A,GK2,OTUD7B,PPFIA3,SDHAF2,MED11,CLIC2,AKIP1,SOS2,PIWIL2,PGM2L1,ROGDI,SLC23A2,GYS1,SLC6A11,RAB37,FOLR1,CAV2,PSRC1,IFI35,FBXO25,CSTF2T,C1QL1,STK38,TIMM10,AP1AR,SMN1,PCDH19,RAB5C,PNP,WEE2,EIF4B,SLC25A4,PTHLH,MRTO4,SMAD3,PPP2R1A,ELMOD1,PLEKHJ1,MLF2,TIMP1,DERL2,TXNL1,IL6ST,TMEM59,RPL23A,LYNX1,KCNIP3,INPP4A,ARCN1,EZH2,RAB9B,AMT,FN3KRP,WIF1,DYRK1B,PHYHIP,STAT6,OR10G7,SNX24,ACADSB,ISG15,BEND5,CMPK1,SNRPA,RAB2A,CTNNA1,WDR44,TRAPPC6B,CCNF,VAMP2,CRBN,CD226,VPS33A,SACM1L,B4GALT3,PDYN,ZFP1,TAPBP,HNRNPA2B1,RCBTB1,GGCT,ATP6V1C1,OR2A25,FANCG,STX6,PLA2G15,MAPK1IP1L,TPPP,RFTN2,RB1CC1,SLC35E1,CAPZA2,NAA60,CCL8,YPEL5,PPID,EGLN3,FOS,DYRK2,OAT,MRPS28,RIOK2,POMP,OS9,RPL26,NFKB1,PRKAG1,PAFAH1B3,HNRNPK,LHFPL2,ACAP2,SCD5,MAFG,TNRC6C,SPTBN1,GIMAP2,GNPNAT1,TOMM40L,FERMT2,EIF3J,UTP23,CHI3L1,RNASEL,PPDPF,TNFSF18,DNAJC8,RAB33A,CRYGD,FAM107A,RNF167,OPHN1,SUMO3,OGG1,ZNF687,CCR3,RAB23,CMAS,PTGER1,CBLN4,RHOJ,WWP1,TMEM50B,IFNG,JUN,CD47,HIRA,S100A8,OR4F6,CRYBB3,TAS2R5,ACTR2,SYNJ2BP,ACP6,TMEM164,APLN,ZNF609,TMCC2,SLCO1A2,KCNK10,NUS1,SRP14,TMEM106C,KRT7,PLEKHA8,MANSC1,WDR3,GJB2,RABL3,ISCA2,UPF3B,ZNF576,GCA,PPP1CB,TRAM2,MPV17,CHST1,FCHO2,EHD1,RFXANK,TRAM1L1,PLAGL1,PAPOLB,SESN2,KLHL15,CLDN8,CXCL14,ADAMTS1,TUSC3,RPL6,SPRR1B,BNIP3L,DDX42,SLC7A14,GMPPA,CYB561D2,MT2A,PPP1R16A,PXMP2,ATP1A2,CXCR4,HSPA14,CDH13,NPY5R,POLR3B,LCN9,BRD9,HAND2,PGR,KCNH1,CCL17,KIAA1191,GTF2F2,DLG4,OR2H2,PAFAH1B2,BICD2,CREB1,SERPINA5,KIAA0408,RNF122,RBM12,RAN,RPP25,GLIPR1,SQSTM1,TMEM177,FMO2,AKR1A1,SPATS2L,NOP58,NFE2L1,RBCK1,MRPS25,CTSD,PGAP2,MRGPRX4,FABP5,OR52M1,NUP107,SCAMP2,SPEF1,SLC5A6,CYP4F8,PRKD3,NLGN2,DEK,PPIB,BPGM,CDKN3,CD164,CCDC42,NPTN,FCAR,POU1F1,CYC1,PTDSS1,ID1,SLC35A2,ENTPD4,ARMC8,DEGS1,CRYBA2,INPPL1,KIF2A,MIA2,BACH1,AP3S2,TMEM33,MRPL47,S100PBP,MPHOSPH10,KLF10,FAF2,BMPR1A,RHCG,ARHGAP21,SCG2,LCN6,OTUD6B,SETD4,RPGRIP1L,OR2W1,CCND1,WFDC13,ACOT13,TMED3,FBXO9,COX7A1,ANP32B,CHST9,CPT2,DCAF8L2,AP1G2,NDNF,PWP2,RAB3C,MTAP,CTSK,CACYBP,URM1,CETN3,NFYA,S100A10,FAM200A,STX8,TGFB1I1,DUSP1,BATF,TOLLIP,SFTPD,CLEC12B,RAB8B,CTNNB1,CYP2D6,SOCS2,DCAF5,ESR2,CDK6,CWF19L1,FAM13B,SNRPD2,ADCY3,SLPI,USP39,CERK,ZNF174,USP38,SYNGR1,ZMAT5,RTP4,LSM6,PRKX,FGF13,PROX1,VPS4A,ENPEP,NAB1,TCP11L1,SOST,SV2B,HPCA,ZNF805,OR2A2,EIF4EBP2,EMC4,GFOD1,SIVA1,SNTA1,SNAPC1,GPR37L1,SPRED1,TSSC4,MAK16,ALDH1L1,POLL,NONO,FYTTD1,NOL4,IQSEC1,TAPBPL,ETV6,RRAGA,RAP2B,ABHD16B,ZBTB42,TNFAIP3,MMACHC,TRAF7,MTMR12,DUOXA2,ST13,RASGRP2,LPXN,DFFA,IL34,UCKL1,ACAA2,RAP1A,WWP2,RABAC1,FBXO30,TIGD7,CD2,POLR2I,PTCRA,CXCR1,NEDD8,HBB,FGF17,KCND2,CCL21,NDUFA5,OXNAD1,RBM23,TMED1,OCEL1,ADAT1,HEXA,BRI3,GAS8,CHRNA7,KIF1C,CDKL2,CD3G,PAOX,BRMS1,IPP,NQO1,TBCE,SPATA2L,NPVF,LMBR1L,AKR1C2,IGFBP4,TAC1,OPA3,HADHA,LEAP2,DHX16,RAB4A,SOX21,TRA2B,OR6M1,NUDT16,GXYLT1,B4GALT6,HSPB1,KCNA2,LHFPL1,HSPE1,CLDN14,ZKSCAN1,SIPA1L1,STAMBPL1,PGBD2,SERPINH1,RPL37A,MSX2,CDC37L1,SNAI3,PELI3,KRR1,NLE1,NAA11,ISYNA1,NDUFB8,APH1A,CXCL1,FRA10AC1,PDIA3,XPOT,WNT7A,LEPR,STX17,ZSCAN1,OR51S1,EIF4EBP3,WDR37,IL23A,PSMD6,SLC39A9,DHX9,FURIN,TXNIP,CREBL2,AQP4,CCL25,GNMT,GLE1,UTS2R,NEK7,PHKG1,LASP1,SPOCK1,MOB3C,FUT8,WBP2,GTF2A1,EIF2B5,SH3GLB2,GALE,OSR2,CXXC5,ENDOD1,CIRBP,ANKIB1,GPR162,APOBEC3C,ZMYND11,SLC7A4,ZNF513,KIAA0040,THRAP3,EEF2,GJA10,SLC25A32,EFHC1,XPO1,EXOC2,XPO5,INTS10,SURF4,TF,CREB3,RNF103,RANGRF,ABCC5,THOC1,DNAL4,FATE1,ATP2C1,RC3H2,PFDN6,LDHA,NUBP2,UBXN10,PCDHA5,SLC20A2,GSK3A,FAM199X,PAEP,NIPA2,RABL2B,CLDN11,TRAPPC1,SPTAN1,SLC35E3,RNASET2,NPY2R,LRP12,ZDHHC14,ADRB1,PKNOX1,FRMD8,RFX4,HEY2,PCDHB8,RBM17,ACTA2,TRIM21,SIX5,ARMCX2,SPR,ARFIP1,GALNT12,PPARG,NFIL3,ZBTB38,HECW1,TRIM37,PTPN1,SETD5,HNRNPC,RMND5B,RBBP7,SLC25A21,PGS1,ZNF593,ARMCX5,PRPF4,IMPACT,CD58,AGER,FKBP14,IDH2,RAB18,ENPP4,CCT5,MCOLN1,PSMB5,SORD,SBK2,SLC39A7,AGK,FBXO32,ANAPC2,HCRT,FGFR1,SHC1,PYGM,OR4K1,PEX3,RCVRN,FAM89B,PPP3CA,CRYGB,KCNJ11,CD200R1,TACR3,CIB3,PRMT2,CAMK2G,TMX4,BUD31,SRP54,CCDC47,TTC4,SCFD1,GHITM,CACNB4,RPL15,TUBG1,SNAP91,MYH2,ALKBH4,HEBP1,SLC7A9,PACSIN3,PGK1,ROPN1B,VRK1,TMIGD1,DNAJC5,S100A6,DYNC1I2,CYP27A1,ZYX,UBAP1,CDC73,LHX2,MMP9,BTF3,JOSD1,P4HA2,SUPT7L,RS1,KIT,LSM3,AFTPH,OR4D9,RARRES2,GRSF1,KPNA1,CSNK2A1,PIWIL4,GSTO2,KBTBD2,ATF4,CTNNBIP1,GNG7,DNAL1,NDST1,TNFAIP8L2,DEFB116,DHRS3,RAB3B,CDCA3,SMAP2,KTI12,FGF1,ABCB1,HBE1,AZGP1,INO80C,PSME2,AZIN1,TBC1D10C,NKX3-2,CCL19,MAGOH,GTF2E2,MLF1,LBH,JAK1,TMEM215,FBXO42,ZNF24,TSEN54,SERPINB10,FZD4,MEST,MTPN,WDR77,ATP6V1G1,LYG2,MFSD6L,MX2,GPBP1L1,ZCCHC10,SYN3,AAMP,OSM,IL15RA,SLC38A9,RMND1,MIOS,FAM78A,PPP1R2,ENY2,RAG1,IMMP2L,MEF2A,DHRS4,SLC35A1,MRPL50,MRPL24,ZNF304,SLC30A5,KLK3,HSD11B1,CYP39A1,MYL12A,SWAP70,LRRC69,FAM8A1,ITK,EIF4H,NCR3,CHDH,GNRH2,SENP5,IDH3B,GALNT4,PYDC2,CYP11B1,GRM2,CTNNBL1,TLR3,GPAA1,JAKMIP1,ADGB,SLAMF9,ZMYND19,TAAR1,CCR6,ID4,SEC14L1,ZNF319,APOBEC3A,ZNF397,XAGE5,GLUL,CNIH4,CDK5R1,NCKAP1,NRP1,KIAA0232,ATPAF2,CLU,LMO4,LTBR,OR4D11,GAL3ST1,CASK,FGFR1OP2,GABARAP,PRPSAP1,GRPEL1,ELMO1,TCP11L2,CHRM4,CCT2,ATP6V0E1,UBE2D3,ARMCX1,UBE2A,OR8B8,IRF1,P2RY1,STRBP,ING1,NAIF1,TRIM23,NHP2,E2F6,ZMPSTE24,EXOSC1,GPR89A,MRPL23,GDI2,GFM2,KLHDC8B,RNF141,DOK4,ARHGAP1,PLA2G5,KLK9,SDR42E1,PDIA6,UBR7,CD99L2,SNRNP27,PRIM2,TRIM32,SLC17A5,ZNF671,SLC25A31,UGCG,MEAF6,LYPLA1,RPS14,LIG3,ATP6V0B,TMEM219,EDF1,ZNF207,POLR3H,C1QC,TRIM3,TMUB1,L1CAM,SNX20,TLR9,FNDC8,COMTD1,APEH,FGD2,DLX1,AKT1,CRABP2,PRRC2A,DPP10,RPS23,SF3B4,IL20RB,DKK3,CCNI,RAB11A,PPIL4,CDO1,LYAR,TOM1L2,EXOC8,PFDN5,UST,RND3,CNP,NUDT3,SPRN,TMEM156,GSTO1,GALNT1,AK2,SOCS5,PSMA3,CCDC69,MRPL13,EHBP1,MDM2,MGP,PSMA6,PCSK9,KBTBD3,AKAP1,CLEC1A,DNAJC24,PARM1,CPSF4,LCN8,AGA,CD63,AGR2,CACNB3,TTC23,PCBD1,NLGN1,MORF4L1,TMEM174,TNFAIP8L3,SLC48A1,CDC42,BACE1,DUSP10,SLC38A1,ACO2,VPS16,CLN8,SYK,FTH1,SNX1,PSEN2,SLC35F1,CCM2,ALB,PIWIL3,IL2RG,TMEM50A,SMG8,LILRB4,MYC,TAS2R39,CD40LG,FEM1A,VPS26A,CMTM6,EEF1E1,CCL28,MKLN1,SHISA2,RAB35,KCTD10,MAB21L1,PPP1R8,OR5V1,PSMG3,GPR173,TOP2B,TIRAP,RPS9,MYL6,GEMIN8,SEC23A,TUSC2,SLC6A3,CASC3,CNKSR3,TCF21,CALML5,VAPB,PNMA1,SP2,HEBP2,CFL1,KLHL3,BRIX1,IRGQ,RNASE6,DPM2,TP53I3,RNF40,RPS26,DDX1,KDELR2,DAP,CCL27,ZC3H11A,HTR1A,TMX2,SFRP1,ELF1,WSCD1,GOSR2,SLCO1B3,FGF23,CYP2R1,SLC25A39,PRR5L,CD14,G6PC3,RANBP6,ZNF704,KBTBD6,PTPMT1,EXD2,UBE2H,FARSA,CD86,MANBAL,PNMA5,SLC2A8,PSENEN,OXCT1,ENO2,OR4S2,WDR82,TLR10,ZBTB25,CD28,NAB2,FXYD6,RNF11,CYTH2,SYNGR2,APOC4,TAF7,CRYAB,PPY,ROMO1,GNL1,ZNF473,SELL,KIAA1143,ATP1B3,DNAJC2,GNB1L,LAMP3,CHPF,REEP6,MATR3,CNOT6,S1PR4,TNFAIP1,FAM169A,TMEM11,CRADD,PPP1R3C,KCNAB1,AGTRAP,SEMA5A,APBB3,MCMBP,CARHSP1,TIMM8A,KLHL9,NPC1L1,TXNRD2,DNAJB4,C2CD2L,AKAP17A,RAP1B,RAD21,SNX14,AIFM1,POLR2G,COQ10B,ACTR1A,LAT2,ACVR1B,FAH,CAMSAP2,CTDSP2,RPL10A,SDC2,LRRC4B,TOMM40,GREM1,COX4I1,FABP4,MPHOSPH6,ANAPC4,GDPD3,ARPP19,NLRP2,MRPL53,HDAC3,RPL29,GLRA2,MAP1S,BHLHE40,PI16,CSNK1E,SKA1,GRB10,ELOVL4,PAK6,CHMP2B,RBP5,DNAJC4,ERVFRD-1,AKT3,POLD4,MAN1A2,CCDC92,CUL3,COX16,OR5A2,CPLX1,PLSCR3,ARMCX3,UBTD1,TMPO,MAD2L2,POLR3GL,COX6A2,RBBP4,FAS,ATF1,ABCB9,LAP3,ADIPOR2,C2CD2,EFHD1,EXTL2,RCCD1,SLC20A1,ALPL,PYGB,TRIM6,HOMER1,PSMB9,PDE8A,FOXP1,SLC4A10,SAMM50,KCNJ8,ENC1,FKBP1A,SRXN1,DNAJC30,P2RY12,EHD3,ST3GAL4,MRPS18B,ZMAT2,DOLK,NT5C2,PHACTR1,SAMHD1,CRYM,TPH2,SPRYD4,KCNS1,API5,LRRTM2,RPL9,TST,RNF5,DGCR8,PAAF1,TFPI,PRKCA,KLHL26,BET1L,MAP3K21,WRAP53,MMD,GAS2,UCHL3,EEF1A1,TRAPPC4,C2CD4C,OR2AT4,TTC33,RPL39,BRD3,SURF6,FAR2,TMEM108,DVL2,TESK1,IZUMO4,ALDH1A3,AHCYL1,ADM2,HNRNPH2,HMOX2,NPTX1,CLIC4,MAGED4B,COX11,SPINT2,RGMB,BCL2A1,TMEM45B,AP2A1,APTX,HRH2,MIF,RBM15B,ZNF189,EEF1B2,ZNF22,TFDP2,C1D,ACTR3B,NTNG2,LRRC8D,ETFB,VIP,HMX1,WNT10B,DGCR6L,FBXO11,RBBP9,SPSB1,ZNF177,ZNF652,HSD17B11,PPME1,C1QTNF1,AUH,TFRC,TTC8,ZNF267,IDE,GGPS1,TSPAN11,MND1,IPCEF1,HMGA1,OR1S1,SH2D5,UTP6,TMBIM6,CCT8,PABPC1L,LSM2,SOD3,DUSP22,GFOD2,ADAMTS20,YWHAH,MRPL49,GABRB3,FAM187B,PLCL1,ICAM1,MTMR2,DNAJC7,CD83,RPL12,KCTD12,UQCRQ,FOXJ3,ORMDL3,RAD23B,USP30,CHN2,TMEM60,HBEGF,CALU,AIF1,HAX1,LRRC20,EGR2,OR1F1,RPS3,YIF1A,OR10Q1,KBTBD13,CA8,RAB3A,DDIT4,SMYD3,KPNA2,LCN12,FAM91A1,CTNND1,NMBR,LGALS3,MAP4,HHIP,LUC7L3,CNTFR,KRT222,PDP2,NEURL2,SMNDC1,POLR2D,SNX12,FGF3,DRG1,CEP85,ERLEC1,SRPRB,NDP,TMEM42,SNX33,MED23,USP13,SDCBP,ATP6V1E2,ZHX3,IL7,SRSF4,NECAP2,SH3BGRL,EXOSC3,PID1,MYL12B,GINS3,ENHO,OPTN,GPR146,KCTD11,CLEC7A,APPBP2,ARPC2,PTGES,ACADS,RNF128,PPP2R5A,VASH1,TLR7,GAPT,RALA,WDR55,FTHL17,F11R,G6PD,ADK,SYBU,EXOC5,SERPINB6,NAA15,EBLN2,CHORDC1,ZBTB16,ANAPC16,OR5B3,BRMS1L,HCST,FBXO34,PAPOLA,DHRS1,IL12A,RHAG,TLR1,OGDHL,CAPG,CCR5,SAR1B,PHF21A,COX5A,SLC1A2,THNSL1,RHBDL3,TRMT61A,CAMP,OMG,GPD2,CELA3B,FBXL7,LBR,CYP11B2,POP7,STYK1,DCAF4L2,RPRD1B,SNRPN,TSPO,LYPLA2,RASL11A,CLSTN3,TBC1D19,RGS6,CSTA,ALOX5AP,ELOVL6,TFPT,NUP35,ZNHIT1,MECP2,SLC25A14,PRDX4,CHST7,SERPIND1,ORAI2,CRYL1,RPL24,OLFM2,ENO1,GNPTG,OR10A7,SERTAD3,MT3,EIF1B,PML,GABARAPL2,DNASE1L1,PSMA4,ZNF790,TAX1BP3,RDH12,TNFSF12,GABPB1,ARF4,TXN,MAF1,RPS12,CYB5D2,ZBED3,DAG1,DUSP6,MTHFS,PPIF,SETD7,TSEN34,FTSJ3,GSTM3,SYNDIG1,TOX,PTRHD1,IRF8,RWDD4,KPNA6,BET1,CYB561,FCER1G,SLC25A46,HEXIM2,TMED4,TBC1D17,HSD17B1,PRDX6,TAX1BP1,AP2M1,KIN,TP53,NFKBIL1,CRELD1,INMT,PKIA,TRAFD1,TRIM35,PPM1B,SENP8,STX7,MGST2,GADD45B,HBA1,OSGIN2,GPC4,MZT2B,LIMS2,NECAP1,MOXD1,RPA3,CCDC160,FDFT1,SIT1,NEGR1,RORB,CKS2,CXCL13,ABHD5,EPHX1,RWDD3,TXNDC12,GFPT1,SDHB,ATG4C,FRRS1,SNRNP48,CENPW,CRLF3,UCN,DEPDC1B,INO80E,PTEN,RLIM,UAP1,THAP7,MGAT5B,CLDN3,ADAM21,DNAJB9,ARG2,RNF144B,GLRX5,RTN4,GNAZ,SIAE,GAMT,ISX,CNRIP1,FKRP,LPAR2,USP15,ELMOD2,OR10A4,PABPC1,GNG12,NTRK2,APOBEC3G,MME,METAP2,SEC22C,CTXN1,MAPRE1,NRN1,MUL1,SMG9,GNG10,FBXO44,DKC1,ARPC3,HR,LRRC3,DNTTIP1,AGPAT5,PLD3,PCYOX1L,CREG2,PIK3R2,PDE1B,UBE2K,DDX23,PCNA,SPRED2,CDAN1,OPRM1,CTSC,NDUFS6,TMEM126B,NXT2,CD247,FZD3,RHOBTB1,IKZF5,HNRNPA0,CHST2,PGRMC1,METTL15,NEUROD2,USP8,TMEM147,COX8A,LGALS8,GPR171,DHX38,PTK7,JAGN1,SNAP29,NDUFAB1,HTRA2,RPL27A,NUDT12,CBLN2,TYW5,BCL7C,IL1A,THBD,OR4D6,CNDP2,PPFIA2,CINP,FBXW11,REEP3,ST6GAL1,CSGALNACT2,HENMT1,CSTF3,RPL7L1,BFAR,TOMM22,UBA3,CBLL1,GLRX,TOR3A,PRR3,IL22,PCDH17,EPCAM,TAGLN3,SAV1,STAT2,SRSF7,CST11,FASTKD5,SFXN2,SNX22,TMEM170B,TMEM117,MRPL34,NDUFB6,GNAO1,CYP21A2,NCDN,UBL3,IMP3,IRAK4,GNPDA1,B3GALT1,COMMD6,KCNJ3,TMEM30A,AFAP1L2,CCDC134,SLC30A7,TCF19,SLC6A6,RPS6KA4,GANAB,TSPAN18,XCL1,BBS5,ZNF664,MLC1,MAT2B,OCRL,DDX46,PDHB,DHX15,OVOL1,RHEB,FBXL14,GPX1,TRIM15,RELL2,GRAP2,RAB27A,RPS7,NPPC,PSMD4,LRRTM3,DAAM1,SCLT1,MRPL11,SLC11A2,PPP2R5E,UBB,SH2D1A,NPSR1,LMAN1,HSPA13,ANKRD34B,LSM10,LARP4B,PMP22,SERPINA1,STX11,OR2Y1,SLC38A7,PGGT1B,OXTR,KCNC1,FBXL19,LAPTM4A,MRGPRX3,SUFU,CCDC86,MTA2,CHIC2,CHCHD4,SLC16A1,TMEM101,HINT2,OR13C8,NUF2,DBT,RAPGEF5,ELOVL7,TPD52,DSTN,DAPK3,RPS27A,PCDHB13,PSORS1C2,POP5,CHAC2,G3BP1,METTL21A,MRPL18,FGFBP1,MFSD5,OLFM3,SCG3,COMMD3,BMPR2,RND2,PPP1R1B,SCGB1D1,ILDR1,NLRP3,CCS,RASD1,IER2,CHPF2,NDUFAF3,HERC4,DKK1,NR2F6,ASNSD1,CNTN2,ZMYM3,CRIP1,PSMB1,BAG3,ZNF365,ORC5,ILF2,OXSR1,RRM1,RBM22,RPS16,KRAS,KDELR1,TOM1L1,SEPHS2,CBR3,CLEC2B,JKAMP,ADD1,CLPB,VDAC1,FEN1,KLF1,ODAM,LANCL2,APOBEC3H,GLRX2,ASB7,PRKACB,ZNF326,PLEKHO1,MYBL2,GSTM5,ERAS,CNOT2,OTOS,CRHBP,CLDN12,GPR176,PKP4,ELF5,CHKB,CCNY,FCGR1A,DNAJC19,VGLL4,SCML2,BIRC2,MTM1,FCGR2B,NUDT7,IFIH1,POLR1B,CER1,CHCHD6,SIAH2,UPK1A,HOXC4,EPS8,RFXAP,SS18,MRPL22,CDCA7L,UMPS,CD1C,UBP1,MAVS,KLHL22,CEP19,CHMP4C,PDAP1,SOX14,CX3CR1,SLCO2B1,IGF1R,FAM177A1,DCTD,SCNM1,MCM4,NR2E1,DROSHA,ORC6,FLOT1,THOC2,STARD4,USP3,CAPN1,CYP2C8,METTL22,ASZ1,TNFRSF1B,CDNF,TGFBR2,CEBPG,ANP32A,SPIN3,RPL23,CLLU1,CTTN,STOM,HP,SEMA4C,SLC2A3,FBXO7,RABGGTB,RCL1,SF3B5,PPAN,IL2RA,AQP2,SMAD1,CHST13,ZNRF1,KLHL24,GABPA,FKBP8,PPP2CB,PRSS12,PPP3R2,TIMP3,TMEM70,MPDU1,VAMP8,TTL,PMM2,PRMT6,EP300,ADAMTS10,MRPL20,PEA15,RNF8,MAP2K1,PLCB2,APOBEC3F,HSD17B6,COPS5,STAT5A,OTX2,MAGEH1,EIF4A2,PRDM4,FEZ1,FPGT,LRRC3B,SOSTDC1,ELOVL1,SSR2,MORC2,TPM3,SNRPB,EFNA3,PTPN4,CHRNB2,GPX7,RIT1,OR10P1,TMEM45A,RNASE1,CGB8,NLRP9,FAM43A,LAMP2,TMEM237,AR,IFI6,OR8B12,PPM1K,GSTP1,LLPH,CCL2,TEX264,SNRK,SERPINB1,SRSF2,GSTA1,UBLCP1,TRAK2,AVPR1B,ST7,KLF9,PIP4K2C,STUB1,FAM181B,NKIRAS2,ACVR1C,RBM38,TMEM41A,IL1R2,SLC22A17,TNKS,CYP1A1,ST8SIA5,PLS3,BST2,PPP2R2C,SPON1,STK4,VRTN,SLC25A10,HINT3,GTF2H5,RPRD1A,DDX50,ZNF821,TRMT112,SLC35F2,SYNCRIP,SLC16A10,VGLL2,DIO1,CLDN9,RNF148,PRICKLE2,MSTN,PPP1R1A,RPL27,MTF1,FAM83C,UGT1A1,MRPS9,LTA,ABCG2,SPSB3,TOR1B,KANSL3,POLB,MNS1,UBASH3B,POLA2,SEMG2,CCNH,KIAA0513,IFNB1,UBL5,BTN2A2,CSH1,TMOD2,GNPDA2,TM4SF19,CRAT,NOTCH2,NAPA,PTPN11,SOBP,AVL9,DECR2,TP53INP1,IQCK,FAF1,VEGFA,CCR1,REN,NCBP2,ASTN1,SOD1,TBC1D13,ATXN10,SMPD2,DTWD1,HDHD3,SHOC2,DDRGK1,RPL32,PSMA1,CLCN6,AK3,HMGCS1,SLC25A12,HARBI1,TMED5,LTB,TCEAL1,PFDN2,USP16,TRIM68,LRRC8B,ETF1,TAF10,PRDX1,FAM53B,NFKBIA,TUSC1,NPW,PREB,ATG7,RNF34,ACBD6,KLF4,DENND2D,COPS7B,OR10A6,OR4D2,SERPINC1,ACP5,HLF,EGFL7,TMEM59L,ATP6V1A,RFC3,SLC7A8,FBXO22,GPM6B,REG1B,UBE2W,PARL,DHRS13,GTDC1,LRRC61,UBIAD1,TSNAX,POLR2B,CHRDL1,PSMB6,ZCCHC17,IZUMO1,PEG10,PIP5K1A,TOMM20,TRAF3IP2,PTGER4,BAHD1,DHRS7B,TERT,CISD1,MORC4,LANCL1,PIK3R3,MKKS,SLC35B4,KRTAP12-4,VPS28,MPZ,SRC,CD2AP,METTL6,RASL10A,TUFM,OR51M1,GNG13,IFNA2,IDH1,HMX2,CHST11,NEUROG2,MTMR6,LUM,SEMA6C,CCDC85B,ICAM3,UNC50,MED31,SH3BP5L,YTHDF1,RPL7,TUBA1A,CELF6,FCGR2A,NAA50,RASGRP3,ENTPD3,RCE1,MGAT1,RGS19,IFIT2,SECISBP2L,RAB33B,MCM3,CDC42EP3,RNF115,PAFAH1B1,SLC25A11,KCTD15,PDCD1,HNRNPD,MS4A7,PSMD12,CKLF,CCT7,RIC3,ARHGAP25,DES,PCDH9,ZRANB2,LIN7B,MYOZ3,EIF4E3,TCAP,VTI1B,FAM162B,GLT8D2,SPATA6,ZNF575,CCL20,MRPS7,ARHGAP5,RSRC1,RPL35A,ZNF668,CD248,KLHL12,SERPINI1,IDO1,PPM1D,SLC25A28,SLC39A3,MSL2,CXCL12,FLCN,STIM1,GRPEL2,LRIF1,TMC7,FTL,TNFSF13,FLRT3,RRN3,D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D2,SUB1,OR52W1,NELL2,DCAF4,ARHGEF6,PCSK2,CPE,CYP4F12,SLC39A13,LRTM2,CYB5R1,MYT1L,USP2,DTD1,REXO2,GPHA2,POC1B,SSBP3,NXPH3,DEFB115,NOL7,SNX2,CAMK1,WFDC5,NSA2,TM4SF1,IRF2,BCCIP,ERP29,PTTG1,INPP5K,NOVA1,MCAT,SEC63,NUDCD3,DYRK1A,DRP2,RAB31,STC1,OR8K1,KLHL32,SRGN,TSHR,SLC25A20,AIG1,NEUROD6,INSM2,EIF2D,EIF2AK2,C1GALT1C1,LGI3,GTPBP2,LIMD2,COPS2,TRIM27,NR4A2,NOSIP,SLC25A45,SFXN1,UBAC2,NME2,CD4,KCNF1,UBXN6,GANC,ACO1,PPTC7,PCK2,RALGAPA2,TAS2R46,G0S2,OR5I1,SATB1,TRA2A,BEND6,PRMT5,CTBP1,EIF3E,CDC42EP4,MSRB3,DDT,JUP,ALKBH3,EXT1,KLRD1,FASLG,SNX5,CFL2,SLMAP,ZMYM2,OR4N5,EXOSC4,BUB3,RNF41,ZNF7,PLP1,DCAKD,XPNPEP1,MGAT4B,CD52,CYP3A5,DCUN1D3,PHF1,LMNA,IRAK1BP1,TIMM8B,TMEM74,BLOC1S3,PHC1,TAAR6,PLXNC1,UGT2A3,GRAP,EPYC,SELENOT,DCP2,MED17,TMEM184C,NOB1,PHF12,ZBTB33,GEMIN7,BAG2,HP1BP3,PACRG,TAS2R16,EIF4E2,IL13,GRM8,UTP15,MCM8,CAMK2N2,CUTA,RMI1,DLAT,RIMS3,MT1A,CD38,PNMA2,ANKRD49,TUBB,LSM14B,ZFP64,COIL,FAM50B,STX10,RING1,ZNF596,MCHR1,SFN,TRAPPC10,SF3A1,GNAI3,PSPC1,DISC1,CHID1,AVPI1,SSR1,NETO2,SMARCD3,RBFOX3,EMP2,LILRB1,OVGP1,GPX2,DNAJC1,HCLS1,TRIM46,GLRB,EHHADH,TRIM63,PAQR9,IL4,TIAM1,THAP2,STBD1,FAM110B,LDLR,FOXP3,OR7E24,VPS4B,TMEM160,RHBDD3,GSTA4,PPP5C,RBM42,PCMTD1,RASGEF1C,MAP2K6,MAD2L1,CA10,ANAPC11,LACRT,SEPHS1,TOMM7,CDC16,GNB1,GLTP,INPP5E,ORMDL1,ASB8,MED30,GHR,CXCL11,MED9,SOCS4,TREML1,PYCARD,CUL2,SLC6A8,ZDHHC15,MAP3K12,RSPH1,FBP2,PPIA,RPS4X,TMOD3,SOX3,COX19,CTSB,DEFB121,NCKIPSD,SKA3,ALKBH2,RPS29,LECT2,POGK,SLC16A4,ACOT8,TRIM52,HNRNPA1,NFE2,IKZF2,CLEC9A,RPL8,PGM1,HADH,NAT9,GABRG2,TFIP11,PRKCQ,WASF3,MEF2B,SMCHD1,B4GALT7,ZSCAN5A,VSTM2A,CLCA1,CNOT6L,CD1E,GTF2IRD1,TRMT11,MRPL40,HTRA1,KIF3B,IKBKB,HELLS,MITF,LCA5L,RPL13A,FAHD1,TRIM8,HRAS,SYT4,WDR20,RPP14,TAGLN2,CDK8,RNASEK,BSCL2,PHF23,COX10,TFG,CYB5A,ELOVL3,MTX2,MAEL,VLDLR,CRB3,DHRS7,CLVS2,VAMP3,SCG5,PHOSPHO2,OR6C4,RFX5,TRAPPC2L,TMEM198,NMRAL1,MAT2A,COX7B2,CMBL,CDKN1B,TAF9,MEA1,HMGN4,SCHIP1,AHSA1,PLEKHF1,ZBTB6,SLC15A1,KCTD16,TRIM62,TEX19,ZNF655,HNRNPAB,GPR78,ST8SIA4,TMEM220,TMEM168,CD200,SIAH1,STRADB,LRP3,NCK1,NETO1,CDR2,PTGER2,C9orf72,NAA30,PSMB4,HERC3,SEMA3C,DOK6,LSM4,IRF9,HSD17B8,DDX39B,CGRRF1,RSL24D1,TRAF1,CLK1,SKAP2,RASSF4,SERPINA3,KCTD20,ZMAT3,BRS3,PRPS1,HAS3,OLA1,TSPAN3,BAD,MGST3,UQCRC1,NOC4L,CRHR1,AKR1E2,SSBP2,PDCD10,GDAP1L1,LRRN4CL,RPL31,WTAP,FKBP2,PRSS35,UNC45A,TBCEL,CYP26A1,GMNN,NUDT1,RALB,TMEM87A,ISG20,DTL,ARL6IP5,CEP70,ABHD2,CTDSPL2,SNN,SNRPA1,CCDC22,KDM1A,NDFIP1,LDB1,TRAPPC3,CSRNP3,NRGN,GMDS,WNT2,BIRC5,ANKH,VPS26B,YKT6,CAMKV,F2,ESYT1,ARL5B,HAPLN2,SAP30BP,EDC3,AANAT,DLG3,B3GALT4,RHOU,TMEM176B,CEBPE,RPL22,ATF3,CTLA4,RBM5,RANBP1,ACSS2,DEFB1,IFRD1,MAP1LC3B,PDLIM3,PRSS37,GFM1,SSH3,HOXB8,EMX2,SEC61G,CENPM,RETSAT,POPDC3,SLC7A11,MET,FZD6,ADIPOR1,PRM1,GAL3ST4,TIMMDC1,SERPINB9,UBE2V1,MT1X,RPLP1,SNX11,PDE6A,IMP4,HELT,TRNP1,ZNF343,DIO2,EGR1,ZNF436,WBP11,STARD7,CHTOP,SYPL1,SETD3,GPR75,TMEM126A,ACTL6A,ACP2,GNPAT,FOSL2,NPBWR1,RPSA,PIK3CG,ARHGAP15,RHOH,ERLIN2,UBE2S,HYAL2,CCDC126,RRP7A,RBM3,CORO1C,RACGAP1,MAGEA4,STT3A,MRGPRX1,HPCAL1,NAP1L5,SEMA7A,TRMT5,OR9I1,BCKDK,ZCRB1,MED4,CYB5B,APOC2,DIS3L,CA14,CEP57L1,OSBPL8,TACR1,ARHGAP19,NACC2,CHRM5,MTA3,DRD3,EMILIN3,CEACAM5,NAP1L3,TIMM13,RPF2,XBP1,TBC1D1,GPR34,THG1L,PDLIM4,GABBR1,ERCC3,ACTR1B,STAP1,HTR2A,SMARCB1,ALG5,DEXI,SUGP1,STARD5,FMO1,ABCC2,CLRN2,DCAF16,GTF3C4,MMP20,PLCXD3,C1QL2,REG1A,OR4K13,DNM2,SOX9,KCNG3,CHST10,JMJD8,ITPRIPL2,GAB1,AKT2,PRSS1,APEX1,PSMC5,TLR5,LCN1,RFC4,HS3ST3A1,TICAM1,GPM6A,OR2D3,PNPO,COTL1,ETFA,PRELID1,RIMKLB,AQP3,ECD,CD59,NEU1,VSTM4,AMELX,PDCD1LG2,GLO1,RAB1A,FBXO31,MAP1B,ZDHHC17,CNOT8,PIGK,PELI1,MLN,KLF12,WDR12,TCTA,PCP2,TMEM231,ADD2,SOD2,SCN2B,TEF,ANKRD10,CDKN2D,ESD,GPR37,ATP6V1D,VWF,PSMB10,CDK17,ART5,TMEM39A,VPS39,MYLIP,SUPT4H1,FAM174A,SART3,IFI16,PTPRZ1,CLP1,CLPX,OR5AN1,INA,CFTR,ATG3,SPDYE4,BMPR1B,OR4M1,HS3ST1,TULP3,PSMD1,BARX2,MPP1,SRM,MED27,RANBP10,ADH1B,BLVRA,RAB32,PITPNA,CRYBA4,CRYZ,FOXC2,PCBP4,MLH3,APOBEC3B,FAM193B,SEC14L5,RPL4,RGL1,SUV39H1,DYNLRB2,CKS1B,SPAG11B,HBP1,RWDD1,SLC25A3,COPE,RBM41,DCTN3,LSM5,PRKCB,IRF2BPL,PABPC5,HCFC2,GJB1,GCHFR,PCYT1B,CSF2,KRT8,PRELP,CHCHD2,SKP1,TPST1,IZUMO2,ZNF200,AGGF1,LCP1,HNRNPH3,HDAC11,SIGLEC5,ATG16L1,DIRAS3,TP53TG5,TTLL10,CCL24,SNRPD1,JUNB,ALCAM,PTPN5,RNF182,TIMM17A,RELL1,SMAD9,LIPA,SLC39A10,MCCD1,TCEA1,HM13,BCAS4,PGAP3,MB21D2,VCPIP1,SRP72,SLITRK1,DDIT3,RPL28,HCFC1R1,CACNB2,FIS1,EDEM2,PIGC,ARFGAP1,STK38L,MVD,CYP4F22,PREP,CDC26,SHC3,SPATA4,CMTM7,TBC1D16,SLC7A1,CA12,ADRB3,FMOD,RAB11B,ARL6,STX5,CCND3,CSRP1,IRF4,LEMD3,LYPLAL1,HSDL2,OPRL1,RNF139,NUP62,SMG5,PLP2,DUS4L,ABCF1,DYNLL1,HINT1,TNPO2,PYCR1,THOC6,CCL11,RAB9A,RXFP2,RPAP3,MARCKSL1,SLA2,IFNAR1,SDR16C5,DICER1,SLC6A7,MAGEB1,IL21,RPL19,HBM,MSN,FGF16,POU5F1,ZNF362,SLITRK5,SAP30,DDIT4L,RNASE4,GLIPR2,SPCS1,TDP1,MID1IP1,SNRNP70,SERINC1,PLEKHF2,LAMTOR2,SLC41A1,PNRC1,UBE2I,UCP2,TMEM106B,MFAP1,MXD1,KRTAP4-1,MAP3K3,ARL11,FHIT,ARGLU1,EZH1,RNF7,TECR,MRPL16,MRPL12,FGR,RCHY1,SPHK2,ZDHHC24,PPT1,B3GALT2,ARF6,DOK5,DCTN4,SEC22A,MAP2K3,CXXC1,RPL7A,LSM12,FIG4,ZC3H14,CBFB,ASPM,EFNA5,ZC4H2,CETN2,TADA1,PITHD1,SMARCE1,SH3BP4,LEP,RIT2,IFNA13,CACNG3,OR4B1,OR5K1,PDE6D,PDZK1IP1,S100B,TNIK,LRFN3,UBE3A,PHTF2,ZCCHC7,PPIL3,DPAGT1,CTSA,LPCAT3,GPR83,KCNIP2,SERTAD1,ZHX1,HNMT,FA2H,ERRFI1,PHF7,MRPS26,HMGB1,TUBA1B,CKB,THAP6,ARF1,EIF2B2,ZMYM6,GNG11,BTBD10,ZBTB26,LRRC14,EMILIN1,PDCD5,PRDX3,COX7B,CDC42SE1,BGLAP,RGS1,SDHC,ASB11,FAM83A,NOL12,RHOG,SEC61A1,TTR,GAD2,METTL18,RSBN1L,SMUG1,SVIP,CDH7,ASCC1,SLC37A4,ZNF770,TPD52L1,DUSP18,UBXN2B,FOXD3,FBLN5,LYRM2,MAEA,KIAA1958,ZNF345,EID2,CXCL10,CEND1,ZNF511,EHD4,FAM81A,SLC25A1,HNRNPF,STAMBP,HOMER3,CXCR3,MAGEB10,GRM1,PCGF6,OR4K2,KCNJ10,SHPRH,SLCO3A1,SPATA2,ADORA1,TAF1D,GJA1,MAGED2,SURF2,SLC29A1,AASDHPPT,RNF222,REEP4,TM4SF20,CCNA2,LSM14A,CAPN2,OR8H3,SLC8A1,ICAM2,ABHD8,YWHAZ,STARD3NL,TM4SF18,TNR,OR6X1,BOK,PLCB1,GPR17,GPC1,PRSS23,ZNHIT6,ARL2BP,ING2,FAM149B1,FRZB,SPP1,TSR2,CHRM3,DMTF1,PLG,DLK2,CDK12,PSMB7,TNFAIP6,FBXW7,EPHA4,KCNJ2,GXYLT2,CITED1,LIAS,ARL4D,TNNI3K,CPLX3,NPY1R,GCLC,PSMD10,ZBED1,CTXN3,TRIM29,CORO6,OIP5,RB1,DPH5,PNMA3,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,GPR35,DDAH1,HFE,NDUFA1,ALG11,PAQR3,CREBZF,NT5DC1,MRPS18C,TRIM36,PROK1,JAK2,COMMD9,STK3,CBLN1,HSPB2,LILRA2,TNKS2,LY6H,PLSCR1,PTP4A3,DCAF12L2,AKR1C1,MRPS11,CSNK1G3,RAB39B,CPLX2,PRND,HUWE1,ABHD10,SREK1IP1,FTSJ1,CNTROB,TTPAL,PMAIP1,CCIN,UBE2L3,MEPCE,CYP3A43,SPEM1,PDE4B,B4GALT4,CAV1,TCEAL8,LXN,YIPF3,RPS2,ITGB5,RGL2,TRIM34,NDUFC2,TMEM205,NINJ1,ICOS,BLCAP,PRL,MPPED2,CDC7,OLR1,SLC19A3,NDST3,FBXO8,MGAT4A,RBBP8,SGMS1,MRPS34,IGSF11,CYP2C9,DUSP21,ATAD1,TRIM45,ZDHHC4,WDR5B,CDC20,XRCC5,ACCS,TIMP4,SNRPG,TBC1D25,AIPL1,PEX13,WDR11,NHEJ1,FHOD3,SLC35B3,TYROBP,SEC13,IL2,NBN,VMAC,TNFAIP8L1,LRRC40,CRISP1,ELK3,DPH3,CD81,MT1E,TRAPPC13,UBE2E2,FSTL1,RHOBTB3,HGS,POLR2L,POLDIP3,DBR1,TAS2R13,COX6B2,RNF133,PRKRA,TSPAN17,PRKCE,ZNF451,GNRH1,WDSUB1,RPL26L1,PHF13,CGGBP1,KLHL1,FOXA3,CARTPT,SESTD1,ABHD12,BANF1,PARP2,NF2,GGH,TNF,PPAT,IL17F,NUDT9,CYGB,TFB1M,SUMO2,LZTFL1,SNRPB2,KLF3,CCR4,CHRAC1,IVNS1ABP,PIK3CA,SNRNP40,FAM83B,JAKMIP2,CDH11,PSMC3,TMEM185A,NDUFS2,PAIP2,LY96,AP1S2,MAD2L1BP,TMEM47,AKR1B1,APEX2,ADORA3,SF3B1,TAB1,CPT1B,ZBTB39,RBM27,CNN3,ANKMY2,PIK3AP1,COX6C,PICALM,LST1,XAF1,VTA1,RPIA,COCH,FEM1C,NUDT2,PEBP4,BAX,GH1,ATP1A3,PSD2,CRTC2,GSTM4,TSPAN15,TMEM38B,NPM3,TRPC1,LYPD6,ELMO2,BCL9,ASPA,CBX3,DR1,GTPBP8,HS2ST1,MIS12,GABRA1,HSD17B10,CAND1,PRNP,TMEM89,TPPP3,ZNF263,CA2,SNX10,USP6NL,MTDH,SGTA,E4F1,TMED9,GSTCD,GTF2F1,DLST,SSX2IP,SYNPR,BCL6,MGMT,TRAPPC6A,MDC1,MTCH2,ITM2B,CCSER2,SP1,IMPA2,TADA3,TRAM1,FUNDC1,AP1M1,ECHDC1,UBA52,SPRY1,RPS10,CLDND1,CCDC106,ETNK2,TBCCD1,TRAF6,VPS72,KRIT1,ROCK2,KCND3,FUBP3,GIN1,TKTL1,RPL18,ZNF581,DUSP3,PDE7A,SUCLG2,CIAO1,ATP8A1,KIF3C,VPS18,GHRL,NAA16,GJC1,SLC12A2,RPS20,RUNX1,SCML1,ZFAND6,TAPT1,MED10,TYMS,SRFBP1,PFKFB2,ARHGAP12,EIF5B,ACER3,MREG,DIRAS2,YTHDF2,FAM161A,PDE12,ANKRD6,FKBP1B,LMO2,LCORL,EDA2R,OR13A1,PSEN1,MAGEC2,RASSF8,CLEC6A,SSBP4,RBP2,TLCD1,AQP11,CDC23,MBD3,DMPK,ELFN1,SYNGR3,TANK,BRAP,MPG,RDH11,PIH1D1,KCTD3,HAUS2,OR5M9,GALC,ELFN2,RP9,LRRC8A,CNPY1,GNGT2,SSPN,LBX1,NKAP,RRAGB,SNRPE,GRIK1,CMA1,DLGAP4,ANXA4,IL18BP,RASL12,GALNT2,GORASP2,THUMPD1,TTC9C,GMPS,PELO,IGF1,CCR7,SNAP25,RXRG,SGIP1,MRPS17,MECR,UBE2G2,MRPL9,FEM1B,FXN,SUPT3H,UPRT,KLRC2,TOX4,CYTH4,TMBIM1,CPNE2,IFT172,RAMP3,IER3,TRIM26,NUCKS1,CENPL,TMEM165,OR8B4,KLHL25,RPE,SULT1B1,SLU7,VEZT,PTP4A2,FAM3C,MFAP3L,IRF7,PRR13,SLC25A5,OAZ1,WSB1,LYZ,TOPORS,ZNF518B,CYBRD1,ADCK1,MACROD1,FAM151B,SLC35E4,CRYBA1,MPV17L2,THAP8,WDR45,NRM,HSPA5,GNA11,SERTAD2,HSPB6,TICAM2,FAM20B,FHL3,PPWD1,PQBP1,GPRASP2,TRIM44,NR1I3,LRP10,CCDC3,VAV2,BTG2,ITGB8,TMEM229B,HINFP,NUFIP2,GNB3,DPEP3,TMEM183A,BTG3,OR1M1,RUSC2,CD9,GRPR,IGFBP3,GADD45A,TGFB2,RBMS2,VPS54,SLC25A27,ZNF622,ATG9A,S100A11,THOC3,GLOD4,PIGA,MX1,BOLL,SAP18,EXOC3,TMEM81,CAP2,SLC22A6,SPG21,TIA1,DDR1,HSPD1,EIF1AX,RNASEH2C,PNPLA4,PIAS1,TMEM115,NPC2,NUPR1,PARD6A,LRRC28,TCEA2,TMEM100,DCTPP1,OR4A47,THAP1,UNC79,CD34,FBXL4,CPXM1,PRCP,EID2B,TRAF3IP3,PIWIL1,RGP1,CCDC90B,TAB2,SRPK2,LDB2,YPEL4,RNASE9,GADD45G,RPA2,TMEM107,TNFSF15,SLC6A2,CD40,AIP,CRY1,ARFGEF1,MED22,NOG,TLR8,PMPCA,PYCR2,ZNF428,PDE2A,TNFSF8,CDIPT,SIN3A,CDK7,PLAC1,PSMD7,SCAND1,RAB6A,CTTNBP2,FKBPL,RGN,APLNR,CYP4V2,SRI,NCAPG2,CNPY3,DTWD2,PSMD3,POLR1D,GPR160,FAM133B,RNF10,GP9,OR51E2,POLE3,KRTAP8-1,ZDHHC16,OR4D5,TEX261,PPP1R11,MDFI,MSH6,RAP2A,P2RY4,FBXW4,TAS2R7,ST3GAL2,CD209,IL2RB,PTGFR,IP6K1,SLC25A24,GLCE,GK5,SSNA1,STAR,RPL10,TRIP4,PDCL,SUPT5H |
| 8.848e-13 | -27.75 | positive regulation of signal transduction | biological process | GO:0009967 | 1593 | 595 | 18204 | 5365 |
IKBKB,IL34,TGFB1I1,RBCK1,CYP27B1,GAPDH,TRIM44,TRIM15,SIAH1,HINT1,C1QTNF1,EPO,S100B,TPBG,IL7,ATAT1,EZH2,OSBPL8,MIR198,CHRNA7,RPS20,FAF1,PPP2R1A,SESN2,RELL2,JUP,GPNMB,IRAK4,ZNHIT1,TNFAIP8L3,KLHL22,TRIM52,F11R,CCDC22,CSNK1A1,F10,SRARP,RPL23,SFRP4,LIPA,MIR212,STK4,FKBP8,CTSC,SPPL3,TP53,SDCBP,RRAGA,TNFSF10,LPAR1,DDX5,NEK7,MIR1-1,CLEC7A,AVPI1,MAP3K3,GHR,ADORA1,FGF22,PTPN1,LAMB2,P2RY1,FGFR1,TMEM33,ACKR3,ITGAV,MIR26B,PRDX2,DDIT3,DLG4,RPS15,TLR4,HOMER1,ZBED3,NETO1,PTPN11,PIP4P1,CRBN,SPHK2,ZNF622,RELL1,LSM14A,GPR89A,NPY5R,ADNP,CITED1,ILK,CASP4,FBXW11,NLRP3,ACVR1,GJA1,PRKCA,DDR1,CSNK2B,CTSD,TIFA,F2,RAF1,SLC39A10,CX3CL1,RBPJ,ROCK2,IL10,MUL1,MAP3K11,FGF3,TWSG1,FGF17,CRLF3,ADIPOQ,TNF,PDIA3,RUVBL1,EDA2R,LY96,TRIM6,RPS3,PHB1,AVPR1B,TESPA1,SEC13,TRAF2,MIR145,CX3CR1,MSX1,KLK6,HFE,PTK7,STX1A,FGF7,HMGB1,MAPRE2,CXXC5,MIR23A,HRAS,PYCARD,AGER,LURAP1,PLEKHF1,CD226,TBC1D24,TMEM198,CXCR4,TAB1,MAVS,GPBAR1,TNKS,DEPDC1B,RC3H2,CSNK1G3,TMEM101,USP8,EEF1E1,DOK4,SLC20A1,IFNB1,CAV1,LANCL2,MEF2C,GPR35,CDKN2AIP,ING2,STAMBPL1,PIM2,CD28,MYORG,HSP90AB1,MYD88,SMAD2,GADD45B,NPTN,IL4,HTRA2,GFI1,ATP2C1,TRIM26,HBEGF,CD4,CD81,MIR146A,TNKS2,ARL6IP5,FAM83B,IGFBP3,AKAP12,TRIM68,TLR3,SOS2,DOK6,CCL5,GPR17,CDC42,PPIA,DUSP19,NUPR1,CSNK1E,FERMT2,IFT172,MYC,SFRP1,FLCN,IGF1R,MIR126,HTR2A,DDT,TEDC2,BCL10,TPD52L1,ATP6AP2,RWDD3,CCL3,MIF,OPRM1,STK3,IL6ST,IRF3,MAP3K12,USP15,ACTN4,MIR1260B,ING5,CAV2,PELO,RIT2,TMOD2,DHX15,IL5,SLC38A9,MAD2L1,NLRP6,FKBP1A,TLR7,IRF7,NUCKS1,RAP1B,IGFBP4,PAGR1,CHGA,SHC1,PRKCB,CCR1,MAP2K1,CTNNA1,CBL,NDFIP1,SOX9,ANKRD6,RHEB,HCST,TRIM22,PROK1,CSNK2A1,MIR20A,GHRL,CCL21,LITAF,PICALM,ADAMTS20,IFI35,BECN1,LTBR,FIS1,MAP2K3,IL1A,TGFB2,MBD5,NOTCH2,KRAS,MIR346,ACTA2,SPRED2,TRIM8,NCK1,GKAP1,LTB,FGF10,RAB29,DKK1,GAS8,CA8,COL3A1,PDE8A,PTPN22,SOX2,CREBBP,PROX1,ENHO,RNF167,MTDH,HAND2,ADRB2,GREM1,SEMA5A,CCR7,CDH13,FGF23,BMPR1A,SMARCB1,NDC80,FABP5,PPM1B,AKR1C2,RPS12,TLR1,TICAM1,LAMTOR2,MIR29A,ADGRG1,BMPR2,IL23A,VEGFA,SEMA7A,TRIM3,OSM,AFAP1L2,PIK3R1,ZNRF1,CUL3,SHOC2,RXFP2,MIR296,OPRK1,NTRK3,LMO3,NTRK2,ICAM1,SERINC3,TAB2,NLGN1,TCIM,DOK5,BIRC5,NLE1,PAFAH1B1,F7,GPR37,PIK3CA,RNF146,MIR15A,LGR4,P2RY12,LYPD6,ROCK1,PDCD4,PDCL,PRKRA,NEO1,SRC,ADRA1A,ANGPT1,TNFSF12,LAMTOR3,CSH1,IL18,RB1CC1,PIK3CG,NECTIN2,MIR140,TRIM21,FASLG,LEP,PHB2,HEXIM1,SCHIP1,NUP62,PML,JMJD8,WBP2,NHERF1,NPSR1,TASL,BMPR1B,NPPC,MAP2K6,DISC1,CHI3L1,HCLS1,IGSF11,DRD1,CRADD,PIH1D1,TERT,MIR16-1,NFKB1,TRAF6,GADD45A,NLGN2,MIR183,TLR2,CYP1B1,NDP,TICAM2,MIR181D,LAMTOR1,GSKIP,TBK1,NINJ1,GRM2,DIRAS1,CCL19,SMAD3,MIR24-1,CD63,DUSP22,ALKAL1,TRIM62,LACRT,BIRC2,TFRC,CCN3,TRIM32,RAP1A,PIK3AP1,TMEM108,ACVR1B,RALB,CD40,SYK,FGF16,STK11,CCAR2,ADIPOR1,TRIM5,STAP1,ATF3,RGL2,FBXW7,NKX3-1,ZDHHC17,RPS7,FCGR2B,S100A8,PRR5L,CLEC6A,TTC23,RRAGB,NMI,EDNRA,VAV2,DSTYK,WNT10B,GPR65,LPAR2,PMAIP1,UCN,MIR210,CD36,CD80,ELAPOR2,OCIAD2,MCL1,GLIPR2,UBE2B,TLR9,PLCB1,RTN4,HDAC3,EMP2,CDC73,TNIK,MIR30B,MIR21,FGFBP1,MIR96,VWF,MIR519D,NACC2,CPNE1,MSX2,SEMA4C,UBE2K,FGR,DDX1,UBE3A,IL12B,FOXP1,PEA15,TMEM100,DNAJC27,ASPM,PTP4A3,CD86,MMP9,UBB,GADD45G,BAX,TRAF3IP2,ERP29,RSAD2,NDST1,AGPAT1,IL6,AKT3,MIR1224,TRIM34,PRL,MIR186,FLOT1,GPR137,PELI1,GPR37L1,OR2AT4,DAPK3,TRAF7,GRM1,MIR10A,HAX1,ADRB1,NEUROD2,MIR449A,IRAK1BP1,TTI2,BST2,FGF1,TIRAP,PLA2G5,NRP1,TFG,PPP3R2,JAK2,LIMS2,PPP5C,PTEN,P2RY10,BAD,G0S2,MIR10B,RAMP3,DVL2,CDK5RAP3,GLCE,GSK3A,PRKCE,EIF2AK2,CD14,FAS,GNAI2,KIT,XBP1,TSPAN5,ADRB3,AR,UBE2N,CARTPT,SOD1,DIRAS2,CRKL,ARRDC3,TGFBR2,MIRLET7B,PAK2,MIR221,MIR675,CALR,BOK,EP300,LPAR6,SNX5,IGF1,CIBAR1,SPRED1,PDCD10,TMEM106A,MT3,KLK5,RALA,GPX1,CYFIP2,CTNNB1,TNFAIP3,GH1,CTSK,GID8,HYAL2,VDR,TXN,BAK1,MIOS,AKT1,TGFB3,IL1B,MIR182,UBE2V1,WNT7A,PPP3CA,FAM53B,RPL26,SMAD4,GRB10,DRD3,PRMT5,AGR2,TLR6,TMED4 |
| 8.907e-13 | -27.75 | ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1) | protein interactions | 56829 | 591 | 245 | 19454 | 5460 |
IGF2BP1,UBE2H,MRPS16,RC3H2,AKT1,RPL7A,CEP85,SRPK2,MRPS28,FGFBP1,HEXIM1,HECTD1,KLF4,RPA2,SSR1,AGO1,SPTBN1,TOMM20,RPS15,LSM12,RNF113A,RAB9A,DERL1,BAP1,PML,NOL12,RPS2,RPL10A,TDRD7,SNRNP70,COPS5,EDC3,FAM20C,DKC1,STX6,TMPO,SURF6,CAND1,DNAJC1,FZR1,RAC2,MRPS9,SYNCRIP,RPL32,ALYREF,NUPR1,RBM34,DNAJC2,H2AX,IMP3,KBTBD4,MTCH2,RPSA,TP53,MEPCE,RPL17,FKBP8,RAB3B,RPL3,MRPS18B,DHX9,MRPL52,FIS1,NSA2,H1-1,LAMTOR1,MRPS25,FTSJ3,BTF3,MYC,OST4,HNRNPAB,ESR2,APEX1,MATR3,NUFIP2,SEC62,TOMM22,BET1,MRPS7,UFL1,FXR2,STAU1,HSPA8,AKAP1,RAB5A,EP300,SNRPA,NGRN,DRG1,ARMC8,CPEB1,YWHAH,MRPL9,YWHAG,XPO1,DDRGK1,IFI16,LAMP2,MDFI,BAZ1B,RAB5C,WWP2,COX14,RPS10,HNRNPL,LYAR,RAB35,SRSF1,FUBP3,RPL18,GLE1,RAB4A,PTRH2,PDHA1,H1-3,DNAJC25,ISG15,TOP3B,RPL28,H1-6,KRAS,HMGN4,RPL31,CMTR2,LSM14A,PABPC1,IVNS1ABP,TXNIP,RPL26,USP14,PPP1CC,CSK,VIRMA,MGST3,NDN,RPL13A,RHOJ,PRKRA,RPS20,TRIM24,CCNF,RPL26L1,RPLP0,ZNF574,DCTN4,MRPS34,GRM2,RBMS2,ATG16L1,UTP23,BRIX1,DGCR8,NPM3,RPL4,MTDH,MAVS,SQSTM1,RPA3,SIRT7,MPHOSPH10,LAMP3,MOV10,GRSF1,SLC25A46,MRPS23,MRPL24,CAV1,ARF6,CGAS,MRPL50,PRR3,HSD17B11,TES,RPL12,PTPN1,SRP14,ARL10,KRR1,LLPH,APOBEC3D,RPL15,FBP1,YTHDF2,MRPS18C,RPS13,PAK1IP1,RPL23A,FAF1,NTRK3,LSM14B,ILK,ZCRB1,BRCA1,RHOB,ZNF668,CUL3,NOP16,RAB11A,PRRC2A,RPL19,RPL35,RPF1,RPL37A,RMDN3,SEC61B,PPARG,APOBEC3C,LARP4B,OTULINL,H1-5,PXMP2,STX7,G3BP2,NOP53,YTHDF1,MCRIP2,EXD2,HNRNPD,AHSA1,MRPS26,RHOG,MAP3K14,ATG9A,MRPS35,RPL7,GJA1,HP1BP3,RPL8,PHB1,STIM1,EZH2,RPN1,MAK16,RAF1,B3GNT2,E2F4,SRSF4,MRPS17,SAR1B,G3BP1,ZC3H7A,RPS24,TRIP4,TMT1A |
| 9.476e-13 | -27.68 | EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) | protein interactions | 5610 | 347 | 159 | 19454 | 5460 |
MACROD1,MIR9-1,SUMO2,LYAR,EIF2S1,TRIM35,MIR141,MIR214,MRTO4,MIR7-2,PHB1,FBXO32,DICER1,MIR140,MIR221,MIR1-1,TRAF6,NCK1,MIR31,IKBKB,DDRGK1,MIR29C,RPL6,PPP2R5A,MIR143,UBXN6,IFI16,MTRF1,KCTD17,MIR155,G3BP1,JAK1,MIR206,PPAN,MIR9-2,TRIP4,RPL18,EZH2,MIR222,TRAF2,SOX2,ISG15,RAF1,RPL19,RPL10,ESR2,MIRLET7D,STAT1,MIRLET7B,DLST,NFKBIA,MIDEAS,NSA2,HSP90AA1,MIR363,FTSJ3,CYP1A1,FAS,MIR98,BTF3,CUL3,HNRNPC,NOP16,MYC,MIR106A,COIL,NOP53,STAU1,UFL1,FXR2,DNAJC3,RFXANK,TIRAP,PRDX3,SURF6,CDC5L,DKC1,MIR429,TOP1,MIRLET7G,RPS16,COG1,RPL35A,CAND1,FZR1,MIR25,EEF1AKMT3,MAP2K6,MIR106B,MIR34A,RPS2,H2AC4,CHCHD1,SNRNP70,MOV10,GRSF1,MIR16-2,RIGI,PTGES3,MIRLET7C,TOLLIP,FARSA,MIR9-3,DHX9,ZC3H11A,NKRF,MIR200A,NUPR1,TAB2,ILF2,MIR17,GPX7,LLPH,MIR20A,EXOSC8,MIR15A,MIR200C,TP53,STRBP,CMPK1,UBE2I,PTEN,PRKRA,EIF2AK2,METAP2,PELP1,MIR16-1,UBE2H,MIR145,MECP2,SPOP,PPP1CC,CARS1,RPF2,MIR29A,MIR107,MIR7-3,FBXW7,MIR34C,MAVS,MIRLET7I,MIR205,MIR10B,BAP1,MIR7-1,IFRD1,RPLP0,SEPHS2,MIR21,GRM2,LMNA,RPA2,CCNA2,MIR1-2,CDC42,SUMO1,FNDC8,TPT1,MIR34B |
| 9.476e-13 | -27.68 | RB1CC1 (RB1 inducible coiled-coil 1) | protein interactions | 9821 | 347 | 159 | 19454 | 5460 |
TMEM33,ATG4A,HUWE1,PSMA5,RIGI,RPL17,FKBP8,RPS13,RNF20,GARRE1,GLCE,PPP1R12A,RAB1A,EMC2,DHX9,RPL3,SURF4,SESN2,PSMC3,TOPORS,HBP1,YTHDF2,TP53,CCDC47,TBK1,AZI2,MAP1LC3B,LBR,ACTR1A,RPS27L,TMPO,ILVBL,LMAN1,HACD3,SYNCRIP,STT3A,SSBP1,GNPAT,RPL24,BECN1,ESYT1,TUBG1,OSBPL8,RPL10A,RPS2,EDEM1,MOV10,SNAP91,HM13,RPL4,KDM1A,MARS1,GABARAP,DAD1,BANF1,RPL27,BAP1,RPA3,SQSTM1,TWNK,IDH2,HSP90B1,RPA2,LEMD3,STAMBP,DYRK2,SEC22B,ATG16L1,GABARAPL2,RPL13A,SEC63,TRAF1,TECR,PSMA6,EIF4A3,RPS3,OPTN,TRIM27,PSMC5,MOB4,SEC61A1,DNAJC10,UBE2H,C9orf72,PSMB2,PSMA2,HNRNPF,RPL28,RPS4X,PABPC1,MAP3K11,SEC11A,SRSF7,TRIM21,PTRH2,RPN1,EZH2,RPS23,AZIN2,SMARCB1,DLG3,ERRFI1,ERLIN2,FAF2,GABARAPL1,TRAF2,SNRPA1,INA,WIF1,HSBP1,HSP90AB1,SRSF10,RPL8,RPLP2,RPLP1,MAP1LC3A,YWHAB,RB1CC1,PSMD3,ATG9A,EIF3D,DDRGK1,TRA2A,EXOC1,CTNNB1,ATG7,YWHAG,YWHAH,SSR3,TRA2B,UFL1,EMC1,NRBF2,DDX5,TRIM5,LARP4B,VAPB,FDFT1,NUFIP2,PGRMC1,RPL27A,TAX1BP1,TUBB,UMPS,DYNLL1,RPL10,PHF21A,RPS9,RPL37A,YWHAZ,ATG3,ZMPSTE24,COP1,SCFD1,HSP90AA1,CUL3,CREBBP,SYCE3,ATG101 |
| 1.014e-12 | -27.62 | UQCRC2 (ubiquinol-cytochrome c reductase core protein 2) | protein interactions | 7385 | 339 | 156 | 19454 | 5460 |
RPA2,HSP90B1,STOM,GRM2,SSR1,ZNF326,CYC1,CDC42,UQCRC1,CFTR,PDHB,FBXW7,RPA3,SIRT7,IDH3A,RNF113A,RTN4,SPOP,ATP1A1,NDUFB10,CTSD,CIAO1,ATP5F1A,HMOX2,TUFM,MGST3,RHOJ,IDE,TECR,UQCRQ,VIRMA,OPTN,CCNF,GANAB,SEC61A1,PSMC5,PTPMT1,NDUFS3,SLC25A24,FBP1,RPSA,MTCH2,INSIG2,RAP1A,HUWE1,HNRNPK,PSMB10,DUSP21,FKBP8,RAB1A,MAP1B,EHD4,ATP5PF,SFXN1,PC,EMC2,POR,CALR,LAMTOR2,COX5A,EMC4,TPM3,ARF6,SPPL3,LMAN1,DKC1,MYL12A,AIFM1,SDHB,COX4I1,RAP1B,VAPB,ATP5PO,ARMCX3,FKBP10,NDUFA5,TOMM22,LAP3,KCND3,MAPKAPK5,RND2,PRDX3,UFL1,NDUFS2,EMC1,SSR3,STAU1,ADRB2,PHB2,COIL,PSMC1,DDX39B,HDAC5,EP300,RAB5A,HADHA,RHOB,YWHAZ,HSP90AA1,COP1,RIT1,COX6B1,NDUFB7,MYC,CUL3,PCCB,ATP5F1B,CYP27A1,ACTB,ESR2,MAD2L2,VDAC2,CYB5R3,DLST,SMU1,EZH2,RPN1,RAB6B,PDHA1,NDUFA12,RAF1,B3GNT2,FAF2,PPP2R1A,CYB5R1,EEF2,KRAS,EMC8,ETFA,VDAC1,UBE2A,TOMM6,HSPD1,NDUFB5,CCT8,NDUFA4,SCD5,SLC25A28,PEX3,NDUFB8,HSPB1,PIK3R1,RAB5C,DDRGK1,RAB1B,TCP1,NDUFS8,EGLN3,UQCRH,HSP90AB1,CCT7,SSR2,RAB35,PHB1,CORO1C,ATP6V1A |
| 1.014e-12 | -27.62 | OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) | protein interactions | 55611 | 339 | 156 | 19454 | 5460 |
TNFSF12,MCMBP,UBE2D3,DDX5,EP300,NMRAL1,HSPA8,BIRC2,ATP5MK,FLYWCH2,BMPR1A,ARCN1,ANXA7,SLC25A3,EIF4B,KCTD12,CDKN1A,IDH3B,PPP1CB,PGRMC1,TOMM22,IREB2,UBTD1,UBE2V2,ACTB,PSMD6,TSN,SSH3,PRDX2,SEC61B,UBE2S,NFKBIA,SETD7,SLC7A11,OSGEP,CYP1A1,FAS,RNF40,PSMA4,MYC,PSMD12,ACVR1B,PSMA1,HNRNPF,BAG2,ERP29,PCNA,EWSR1,ABCF1,NDUFA4,CCT8,SLC25A5,RNF126,CRKL,FAM136A,CHMP4C,OTUD6B,RANBP1,DHX15,UQCRH,EGLN3,AGK,CCAR2,TRIR,MAGED2,STAMBPL1,SMAD9,TRAF6,DDX23,UBE2D1,QPCTL,CTNNB1,FAM174A,UBE2E2,PRDX1,HSPA5,USP8,FBXW7,TTR,KDM1A,IRF7,TCEA1,MAVS,GPX4,BAP1,MAIP1,DVL2,RPA3,STAMBP,RPL26L1,SNRNP27,TPT1,UBE2W,UBE2L3,TXN,TRIM54,MSN,RPS20,EIF4A3,STUB1,UBE2H,ATP1A1,NAPA,SMAD2,UBE2E3,CHORDC1,AR,UTS2,MTPN,CCNB1,SLC25A1,CAPZA1,RIGI,RNF20,DUSP21,CTNND1,TRIM63,SRPRB,HNRNPK,CSE1L,NEDD8,HSD17B10,SLC16A1,MRFAP1,PSME1,SLC25A11,NOSIP,ACVR1,RP9,H2AX,MAP1LC3B,YTHDF2,TP53,RRM1,UBL4A,GATAD1,RNF128,DSTN,UBE2G2,UBE2N,SDHB,AIFM1,PTPN1,CD274,SMAD3,MAP4,TSNAX,USP15,DNAJC7,PSMD7,SMAD4,MPG,ELOC,CSNK2A1,BMPR1B,KARS1 |
| 1.014e-12 | -27.62 | RNF2 (ring finger protein 2) | protein interactions | 6045 | 802 | 316 | 19454 | 5460 |
MFAP1,ARCN1,KLF3,ABCB1,ATP5PO,ADNP,ZFP64,ATP2C1,ATP5MK,CSRP1,G3BP2,SKP1,YTHDF1,SAMHD1,SMARCE1,PYCR1,FYTTD1,SNRPD2,SNRPD1,SARM1,RAN,CHCHD3,ITM2A,MAD2L1,UBE2V2,OTUD6A,RPL19,ERH,SNRPB2,RBBP4,RPL7L1,SIAH1,FAF2,RPL29,RAF1,RPS11,SART3,RPN1,CHMP4C,UBE3A,RPS24,NDUFA4,PSMD12,MRPS17,SSRP1,RAD21,PCGF6,TRIM26,PCGF3,G3BP1,CBX7,HNRNPA1,TRA2A,EIF3D,HMGA1,TAF7,PRPF19,CLPX,MRPS26,UBE2D1,WDR12,RPLP1,HP1BP3,THOC2,RPL9,WDR6,MRTO4,PHB1,MYEF2,OCIAD2,SRSF10,NOP58,RPL7,AGK,KCTD10,KLF12,SF3A1,PSMC4,CCND1,TIMMDC1,SNRPN,SEC22B,NOL7,RPLP0,EPHX1,HNRNPH3,RARS1,WTAP,CDK1,GRM2,MTDH,PNO1,NHP2,CXXC1,GTF2I,PDHB,FBXW7,RPL4,SMC4,RPL26,GMNN,TUFM,AR,ZNF687,SEC13,NAPA,XPOT,TRIM27,TRIM24,SFXN2,RPS12,PELP1,TUBA1B,EIF4A3,TECR,UBE2L3,SCML2,GNAI2,VIRMA,RPL22,LDHA,RPL13A,RPL15,UBE2V1,YTHDF2,CCT5,MRPL11,POLR2G,SRP72,DMAP1,RING1,RPL23A,TMX3,H2AC25,SLC25A10,ZNF787,SFXN1,RPS13,SMN1,THRAP3,MOV10,CALR,MPHOSPH10,PWP2,AIFM1,H2AZ1,RCHY1,KRR1,MDM2,TOP1,THOC1,AKIP1,LAP3,RPL27A,ZC3H14,MXD1,PLAA,SF3B1,PCGF2,YAF2,DDX5,CCDC9B,DDX39B,SNRPA,RFC4,XRCC5,SAP18,MRPS7,UBE2D3,FXR2,HNRNPA0,RER1,STAU1,PHB2,MYC,HNRNPAB,HNRNPC,LDHB,RPS26,RCL1,THOC6,NSA2,CIRBP,TFDP2,FTSJ3,RPS6KA4,CHTOP,H1-10,SF3B4,POLR2B,RPL10,ATP5F1B,SOX2,TRAF2,H1-3,EEF2,RPS7,MAX,SUPT5H,MTA2,TUBB4B,GLE1,RUVBL2,EWSR1,SEC11A,BAALC,RPL31,ABCF1,SESN3,RPL28,HNRNPDL,PAX6,POLDIP3,CBLL1,RUVBL1,XPO1,QPCTL,UTP6,NGDN,DDRGK1,IQSEC1,BAZ1B,DDX50,RPL6,UBE2E2,WWP2,PTDSS1,POU5F1,MAGOH,EED,MAGED2,RBM5,FUBP3,SRSF1,PEG10,ZNF740,EIF2S1,NOB1,RPS10,HNRNPL,DYNC1I2,SNRPD3,LYAR,GTF3C4,UBE2W,E2F6,UTP15,ACACA,LUC7L3,ZNF326,RPL27,MAPKAPK3,ZC3H15,MARS1,UBE2K,RPS15,KDM1A,RPS17,RPF2,SMARCA5,RPL7A,UBE2H,RRP7A,CISD1,UBE2E3,CSNK2B,EIF2S2,MACROH2A1,ZNF330,PSMA6,MRPS21,H2AX,ZMYM3,IMP3,STRBP,ATP5PB,RRM1,TP53,MTCH2,RPSA,NUPR1,PHC1,PSMC3,TFRC,CBX3,TFCP2,IK,DNAJC2,RPL3,ABCE1,DHX9,SLC25A11,RPL17,H3C1,CSE1L,HNRNPK,SCML1,CSNK2A1,TPM3,ACOT8,AKAP8L,RPS2,RPL10A,SMCHD1,BECN1,H2AC4,RPL24,SNRNP70,SYNCRIP,RPL32,COMT,ALYREF,DKC1,CDC5L,RNF222,PLG |
| 1.054e-12 | -27.58 | regulation of cell migration | biological process | GO:0030334 | 1061 | 417 | 18204 | 5365 |
P2RY12,ROCK1,MIR135B,MIR15A,MIR143,ARHGAP5,F7,TIAM1,CD47,ICAM1,BMERB1,IFNG,CBLL1,PIK3CG,THY1,MIR939,KRIT1,CD200,MIR140,RNF41,MMP28,SST,SRC,DAG1,ANGPT1,ZNF609,ADGRG1,BMPR2,MTA2,IL23A,SEMA7A,VEGFA,NF2,MIR29A,TIMP1,CCAR1,ABHD2,NFE2L2,MIR137,FGF23,BMPR1A,MECP2,FLRT2,MIR296,SOX14,MIR218-1,NTRK3,MIR551A,FZD4,MIR493,PIK3R1,NR2E1,BRMS1,CCL1,TRIM32,CCN3,GLUL,TMIGD3,MED23,SELENOK,DUSP1,STC1,VSIR,CERS2,SMAD3,MIR101-1,MIR24-1,DUSP22,FBXW7,HDAC6,ELP3,NOG,PRR5L,GFUS,CREB3,ADIPOR1,STAP1,FGF16,MIR205,TMIGD1,ACVR1B,CD40,CCL23,FUT9,DRD1,MIR491,TERT,MIR16-1,CCL4L1,PLP1,NHERF1,CCL2,DPP4,CCL19,CYRIB,TRIB1,STAT5A,MIR181D,GADD45A,RARRES2,CYP1B1,MIR222,MIR379,TP53INP1,ABHD6,IL6,MMP9,PADI2,FOXP1,GNRH1,MACIR,ACVR1C,MIR223,FGR,LDB2,MIR185,MMP14,OXSR1,MIR10A,TMEM196,IQSEC1,MIR449A,EMC10,DAPK3,VEGFC,AKT2,PLXNC1,CD274,FAM89B,AKT3,FUT1,MIR885,MIR210,MIR129-1,NUS1,SIN3A,RIGI,PAX6,MIR204,ELP6,SEMA4C,FGFBP1,MIR21,CD9,MIR519D,PLCB1,RTN4,EMP2,CD99L2,GLIPR2,RGCC,RBBP4,HYAL2,TCAF2,CCL24,SAP30,IGF1,SPRED1,PDCD10,PIK3R3,CALR,MIR92B,ITGA2,SEMA3C,MIR182,LMNA,FAM107A,PPP3CA,WNT7A,AKT1,IL1B,STARD13,PRKCE,MIR448,MIR10B,ATP8A1,PTEN,JAK2,FGF1,BST2,CCL28,TIRAP,NRP1,MIRLET7B,TGFBR2,STK26,PLAA,MIR130A,MIR221,MIR497,KIF2A,MIR492,CRKL,MSN,XBP1,MET,LMO4,MIR320A,MIR206,GNAI2,KIT,MITF,ITGA6,TNFAIP6,CYGB,MIR1-1,CLEC7A,GPR173,MAP3K3,SYNJ2BP,MIR34A,SOD2,MIR133B,SDCBP,MIR188,SDC4,LPAR1,CXCL8,MDM2,SVBP,STK4,CLIC4,MADCAM1,RRAS2,ST3GAL4,CCL11,KLF4,ARHGEF39,CCL8,MIR590,TLR4,MPP1,VASH1,FGFR1,ITGAV,ACKR3,RAC2,ADORA3,ADORA1,FGF22,RAP2C,MIRLET7G,OSBPL8,MIR335,LGALS3,MIR638,IL34,SP1,CXCL13,MIR212,PPARG,MIR503,PTGER4,F10,MIR30A,GAB1,RNF20,RAP2A,STK24,MIR193A,CDKN1B,MIR711,GPNMB,JUP,AAMP,RHOJ,CX3CR1,MIR145,PRKX,ING1,RAB11A,DDRGK1,FGF3,RBBP7,MIR505,FGF17,TNF,ADIPOQ,MIR1298,CX3CL1,TBCCD1,BRMS1L,MIR640,ROCK2,XCL1,TBC1D24,EMILIN1,CXCR4,PLG,MIR23A,HRAS,PYCARD,ZNF304,MIR361,AGER,DUSP10,RHOB,MAPRE2,FGF7,HMGB1,CORO1C,MIR495,CLDN4,EPHA2,CXCL12,PHACTR1,CDK5,NTNG2,CCL18,MIR338,MIR424,CXCL10,TNFRSF14,TMSB4X,ARF6,CLDN3,CCR2,FOXC2,AIF1,CSNK2B,MIEN1,CDH11,CXCR3,CHST2,PRKCA,GJA1,MIR214,CCL25,LDB1,ACVR1,FERMT2,CCL17,SFRP1,MIR126,IGF1R,TMSB10,SEMA6C,CDC42,HSPB1,GPSM3,CCL5,AKAP12,DEFB124,EPHA4,MIR200A,MIR3173,CSF2,CCL3,MIF,ATP5F1A,IL12A,DDT,MIR132,SWAP70,MEF2C,MIR150,MSTN,ING2,CAV1,MIR149,UBE2I,S100A11,CLDN1,IGFBP3,PTN,HBEGF,CD81,MIR146A,MIR208A,HSPA5,LDLRAD4,MYD88,MIR342,TACR1,MIR31,IL4,FGF10,ATP5F1B,ADAMTS1,MIR9-1,NCK1,DPEP1,ACTA2,IL1A,DUSP3,MAP2K3,TGFB2,CCR6,SEMA5A,MIR152,CCR7,CDH13,TNFSF18,PROX1,ADTRP,CCL20,GREM1,RAP2B,COL3A1,WASL,SAP30L,CCR1,HDAC5,TWIST2,CD200R1,ATP2B4,MIR200C,MIR29C,CD151,ACTN4,SNAI2,PRCP,MIR20A,CCL21,TNR,SOX9,CTNNA2 |
| 1.077e-12 | -27.56 | Eukaryotic Translation Elongation | REACTOME pathways | R-HSA-156842 | 96 | 64 | 10285 | 3229 |
RPL12,RPL31,RPL9,RPL18,RPL22,RPL17,RPS3,RPL26L1,RPL35,RPL10,RPL19,RPL23,RPS15,RPL29,RPL10A,RPL26,RPS27L,RPS7,RPL39,RPS10,EEF1B2,RPS12,RPL27,RPS2,RPL4,RPS11,RPS23,RPL37A,UBA52,RPL7,RPS9,RPSA,RPL6,RPS20,RPS24,RPS16,RPL3,FAU,EEF2,RPL32,RPL35A,RPL24,EEF1A1,RPL23A,RPL7A,RPL28,RPS14,RPLP2,RPL8,RPS5,EEF1G,RPS26,RPL15,RPS17,RPS28,RPLP1,RPS4X,RPL13A,RPS29,RPLP0,RPS13,RPL10L,RPL27A,RPS27A |
| 1.094e-12 | -27.54 | WDR77 (WD repeat domain 77) | protein interactions | 79084 | 353 | 161 | 19454 | 5460 |
RAF1,SUPT5H,MTA2,POLR2C,RPS11,HGS,SNRPE,LSM10,BAG2,CCT8,PPAN,RPS4X,RPL28,RPS27A,HNRNPDL,COPS4,CHCHD2,HNRNPF,RBBP7,KRAS,G3BP1,HNRNPA1,DDRGK1,ZNF207,IFI16,RPL23,YWHAB,MAGOH,GJA1,CORO1C,USP46,RPL8,RBM5,NKX3-1,EGLN3,CCT7,PAIP1,RPS10,OSBP,TCP1,SPTAN1,SNRPD3,PPP1CB,ELK4,WDR77,MYL6,HSPA8,CRY1,RAB5A,DDX5,RPS28,HTR1A,G3BP2,UFL1,FXR2,STAU1,GPC1,SNRPB,COPS7A,CREBBP,MYC,CUL3,CUL2,RPS26,RPS5,RIT1,CCT2,CIRBP,CHTOP,PSMD14,PRMT5,SF3B4,SNRPD2,SNRPD1,GTF2F1,PELO,POLR2B,PRRC2A,RPL10,ESR2,APEX1,PRDX2,RBBP4,RPL15,SMAD1,UBL4A,ATP5PB,FBP1,RPSA,TP53,CCT5,CDK4,ILF2,RAD1,TBC1D4,TAF2,CDK8,RPL23A,ABCE1,DHX9,EMC2,PALM2AKAP2,PQBP1,PHF1,RPS13,SMN1,CAPZA1,CTNNBL1,LSM4,TPM3,FAM20C,CDK12,LSM3,RPS2,CRBN,HRAS,SYNCRIP,ALYREF,MYL12A,FZR1,THOC1,CDK7,SF3A1,ATG16L1,SPTBN1,SAP30BP,RPS14,CCND1,SNRPN,PPP1R8,MYL12B,RPL26L1,HNRNPH3,UBE2M,ZNF326,METTL14,HNRNPH2,FLCN,SQSTM1,BAP1,SIRT7,CXXC1,HSPA5,WDR3,RPL26,FBXO7,AR,ZMYND19,RPL7A,PDCD4,UBE2H,RC3H2,LSM6,PSMC5,MACROH2A1,CCNF,RPS3,EIF4A3,SMURF1,VIRMA,RPL13A |
| 1.126e-12 | -27.51 | RPL27 (ribosomal protein L27) | protein interactions | 6155 | 378 | 170 | 19454 | 5460 |
RPS3,PSPC1,OPTN,METAP2,PRKRA,RPS12,RPS20,PTEN,NDN,RPL10L,RPL13A,RPL22,RPL7A,RPL26,RPS17,PPP1CC,MECP2,RC3H2,NRP1,UBE2H,DNAJC19,RPL27,BAP1,RPA3,RNF113A,RPS15,NPM3,RPL4,HMGB1,FBXW7,PIAS1,HSPA5,BRIX1,ATG16L1,RPS14,TPT1,FUT8,CDK7,SMYD3,CFTR,RPA2,METTL14,HEXIM1,RPL26L1,RPLP0,RPL12,RCHY1,RPL32,FZR1,DNAJC1,RPS16,CAND1,RPL35A,PRNP,RBM42,TMPO,ENY2,MOV10,EMC4,COPS5,CD81,CSNK2A1,HDAC6,API5,CRBN,SNRNP70,RPL24,RPS2,RPL10A,MAP1B,SNIP1,TCOF1,RPL23A,RPL3,DHX9,MRPS33,HUWE1,VRK1,MRPL22,RPS13,PSMB10,MEPCE,RPL17,FBP1,KBTBD4,UBL4A,TP53,RPSA,YIPF4,RPL15,TFCP2,DNAJC2,IK,SRP72,CMTR1,PELO,RPL37A,SEC61B,RPS9,MATR3,RPL35,RPL19,RPL10,MYC,CUL2,CUL3,PSMD1,BTF3,RPS29,H2AZ2,BRCA1,RPS5,ICAM1,RPS26,NSA2,RIT1,EP300,RAB5A,UFL1,STAU1,G3BP2,RPL27A,MTF1,TMEM115,EMC9,PIH1D1,CSNK1A1,SLC25A3,RPL9,FOLR1,RPL8,MRTO4,PHB1,RPLP2,RPLP1,RPS10,RPL7,RPL6,WWP2,YWHAH,DDRGK1,MAP3K14,AGR2,RB1CC1,DDX1,DRG1,RPL23,DICER1,RPL31,PABPC1,RTCB,RPS24,G3BP1,KRAS,TNF,TRIM37,VDAC1,RPL28,RPS4X,RPL29,SOX2,DNAJC25,MSX2,RPS7,EZH2,CHMP4C,RPS11,RPL18,SART3,RPS23 |
| 1.168e-12 | -27.48 | Peptide chain elongation | REACTOME pathways | R-HSA-156902 | 92 | 62 | 10285 | 3229 |
RPL24,EEF1A1,RPL35A,RPS14,RPL23A,RPL7A,RPL28,RPS20,RPL6,RPSA,RPL3,EEF2,FAU,RPL32,RPS24,RPS16,RPL13A,RPS29,RPLP0,RPLP1,RPS4X,RPL27A,RPS27A,RPS13,RPL10L,RPL8,RPS5,RPLP2,RPS17,RPS28,RPS26,RPL15,RPL17,RPS3,RPL22,RPL19,RPL26L1,RPL35,RPL10,RPL12,RPL9,RPL31,RPL18,RPS11,RPS23,RPS12,RPS2,RPL27,RPL4,RPL7,UBA52,RPS9,RPL37A,RPL29,RPL10A,RPS15,RPL23,RPL39,RPS10,RPS27L,RPL26,RPS7 |
| 1.168e-12 | -27.48 | Viral mRNA Translation | REACTOME pathways | R-HSA-192823 | 92 | 62 | 10285 | 3229 |
RPL35,RPL10,RPL26L1,RPL19,RPL22,RPS3,RPL17,RPL31,RPL9,RPL18,DNAJC3,RPL12,RPL37A,RPS9,UBA52,RPL7,RPL4,RPS12,RPL27,RPS2,RPS23,RPS11,RPL26,RPS27L,RPS7,RPS10,RPL39,RPL23,RPS15,RPL10A,RPL29,RPL7A,RPL28,RPL23A,RPS14,RPL35A,RPL24,RPS16,RPS24,FAU,RPL32,RPL3,RPL6,RPSA,GRSF1,RPS20,RPL10L,RPS13,RPS27A,RPL27A,RPLP1,RPS4X,RPLP0,RPL13A,RPS29,RPS26,RPL15,RPS28,RPS17,RPLP2,RPS5,RPL8 |
| 1.173e-12 | -27.47 | TOMM22 (translocase of outer mitochondrial membrane 22) | protein interactions | 56993 | 356 | 162 | 19454 | 5460 |
PDHB,ABCC2,GRPEL1,TOMM20,RPA3,SPCS2,MAVS,STOM,HSP90B1,USE1,SAMM50,TMX4,CTDSP1,RPA2,CYC1,FAXC,FBXL19,UQCRC1,MGST3,GNAI2,TECR,UQCRQ,NECTIN2,SCAMP2,UQCRC2,SLC1A1,RCBTB1,EIF2S2,TRIM23,DNAJC10,NRP1,ATP1A1,C9orf72,TOMM40L,HUWE1,FKBP8,DUSP21,ARF4,PSEN1,ATP5PF,SFXN1,HSD17B10,SLC16A1,NDUFS3,TFRC,SLC25A24,ILF2,MTCH2,MRPL11,ATP5PB,MTARC2,MGARP,TMED9,PLGRKT,ATP5PD,RAB39B,FAM118B,MYL12A,TOMM70,ARL10,COX4I1,EHBP1,AIFM1,PTPN1,TRAK2,STARD3NL,CDCA3,PROM1,SLC2A1,SLC25A46,DPP4,KARS1,CALR,MFN1,SSR3,PHB2,NDUFS2,UFL1,ARMCX2,PXMP2,EXD2,HSDL1,AKAP1,TTC1,HADHA,ARMCX3,MAP2K1,VAPB,ATP5PO,KCTD12,SRARP,FAM3C,SLC25A3,MTX2,TOMM22,RAB6A,TIMM29,EHD1,TAX1BP1,RPL35,LAMTOR3,SPCS1,ACTB,ATP5F1B,ESR2,CHCHD3,CYB5R3,DLST,DIO2,LMBR1L,S1PR4,ANAPC2,RMDN3,ATP1A3,LAMTOR1,MED10,ILK,RIT1,BAX,HNRNPC,MTG2,PCCB,TOMM40,ATP5F1D,VDAC1,USP30,KRAS,TOMM6,SYPL1,SCYL2,EWSR1,AQP3,PDHA1,VPS33A,RPN1,HGS,POLR2C,NDUFA12,TOP3B,STBD1,FAF2,PPP2R1A,TOMM7,TUBA1A,SPTAN1,SNRPA1,RPS10,RAB1B,COX14,WIF1,NDUFS8,EGLN3,PHB1,THY1,CORO1C,MAGED2,HNRNPD,RAB5C,SYNJ2BP,CLPX,FEM1B,DDRGK1 |
| 1.217e-12 | -27.43 | ACAD9 (acyl-CoA dehydrogenase family member 9) | protein interactions | 28976 | 409 | 181 | 19454 | 5460 |
FAS,NTRK3,HTRA2,MTG2,AUH,KDSR,PMPCA,PYCR1,OTUD7B,MRPL23,NDUFAF4,PARL,ATP5PO,NDUFA5,OTULINL,TIMM29,HSCB,SRM,EXD2,TSPAN15,ATP5IF1,HADHA,RHOG,MRPL18,MRPS26,CLPX,MTRF1,MRPS35,STOML2,MMUT,NDUFS8,PHB1,GATD3,VAMP2,NDUFS6,HSDL2,FAF2,ATP5F1D,ETFA,MRPS17,IMMP2L,PREPL,HSPD1,THNSL1,NDUFA4,HINT2,MRPS11,COX8A,DNAJC19,PYCR2,TUFM,VIRMA,MRPL53,CCNF,ACAT1,MRPS34,RPL26L1,MTRES1,PCK2,TIMMDC1,CDK7,MRPL17,PDHB,FBXW7,POLDIP2,MRPL20,RPA3,TMEM126B,NDUFC2,SLC2A1,GRSF1,ATP5MG,EMC4,MRPL50,DBT,ATP5PD,MRPS23,MRPL24,SLC25A12,HRAS,AIFM1,NDUFS3,MRPL49,MRPL11,NDUFA2,PPIF,MAP1LC3B,BCS1L,DNAJC30,TTC4,HSPE1,FASTKD5,MRPL22,MRPS18C,EMC2,HSD17B10,MRPS25,HNRNPAB,ISCA2,ATP5F1B,FBXO22,ESR2,LMBR1L,TACO1,DLST,MTG1,CCDC90B,RETREG3,MRPL13,UBAC2,EIF4B,MRPL12,NDUFAF3,EMC1,NDUFS2,PHB2,OXCT1,MRPS7,PDSS2,EP300,NDUFV2,MRPL9,HNRNPL,PNPLA8,RMND1,NUDT19,PDHA1,NDUFA12,ETFB,COA1,KGD4,VDAC1,HNRNPDL,UQCC2,NDUFB5,MRPS16,OAT,NDUFAF2,SYNGR1,MRPS28,PTPMT1,QRSL1,P2RY12,RPA2,SSR1,CCNH,NDUFAB1,CDC42,MRPL10,NME4,MRPL40,LPAR1,SLC25A51,MRPL41,OGDHL,GRPEL1,TWNK,GFM1,DLAT,CHCHD1,TMEM70,COX5A,SDHB,SYNCRIP,SSBP1,MRPS9,ALYREF,COX4I1,MGME1,ATP5PB,BPIFA2,MTCH2,MRPL47,HADH,APOO,METTL15,MRPS33,MRPL52,ATP5PF,MRPS18B,THG1L |
| 1.218e-12 | -27.43 | RPS6 (ribosomal protein S6) | protein interactions | 6194 | 779 | 308 | 19454 | 5460 |
CDK9,MDM2,MRPS23,NOP9,MRPL24,ZNF7,DCUN1D1,RPL35A,PRNP,TOP1,OLFM2,PWP2,RPL12,KRR1,ARL10,RCHY1,BRD3,NME2,MPHOSPH10,HDAC6,APOBEC3F,H2AC14,MOV10,SPATS2L,RPS13,ARF4,RIGI,PAK1IP1,NOC4L,VRK1,RPL23A,NKRF,ILF2,SRP72,LLPH,MAP2K3,LBR,EEF1A1,RPL15,FBP1,MRPL11,DEK,RPL22,VIRMA,NDN,RPL13A,PRKRA,RPS12,RPS20,PTEN,PELP1,CCNF,EIF4A3,METAP2,MAPRE1,RPL26,AR,PPP1CC,DNAJC8,TUFM,ZMYND19,BRIX1,UTP23,AATF,EIF5B,NPM3,HMGB1,FBXW7,RPL4,RPA3,PNO1,SIRT7,ZNF574,RPL26L1,RPLP0,MRPS34,LMNA,METTL14,H2AC7,GRM2,CDK7,RPS14,NOP58,RPL7,RPLP2,HP1BP3,RPLP1,RPL9,FOLR1,RPL8,MYEF2,MRTO4,PHB1,MRPS26,RSBN1L,RPL23,ZCCHC9,WDR12,HNRNPA1,MRPS35,RPS27A,GTF3C3,SAR1B,RAD21,RFC3,G3BP1,TNF,TRIM26,SLC39A7,RPS24,SLC25A5,TRIP4,PPAN,RPS11,EZH2,CHMP4C,RPL29,MAK16,GTF2E2,B3GNT2,RPL19,MRPL23,RPL7L1,RPF1,RPL35,RPL37A,ZMAT2,SEC61B,RPS9,ZNF22,FAU,ARF1,RPS5,HSP90AA1,RIT1,NOA1,RHOB,BRCA1,ZCRB1,RIOK2,ZNF668,MRPL16,RPS29,NOP16,CUL2,CUL3,COIL,G3BP2,NOP53,MRPL57,TXNL1,CCDC86,HADHA,CFDP1,NKAPD1,UPF3B,MFAP1,EMC9,RBM42,DKC1,SURF6,CDC5L,FZR1,SPPL3,RPS16,CAND1,RPS27L,SYNCRIP,MRPS9,RPL32,RPS2,AKAP8L,CDK12,NOL12,RPL10A,TUBG1,RPL24,SNRNP70,CD81,COPS5,CSNK2A1,CMSS1,ENY2,SRSF12,MEPCE,RPL17,IMP4,MRPS18B,RPL3,DHX9,MRPL52,SNIP1,HBP1,GNAI3,DNAJC2,RBM34,H2AX,PLA2G12A,KBTBD4,IMP3,STRBP,UBL4A,SRFBP1,RPSA,MRPL47,TP53,SMURF1,RSL24D1,SRPK2,BCCIP,RPL10L,RBMX2,PSPC1,RPS3,LIG3,ELAVL2,UBE2H,MRPS16,MECP2,TRIM23,RC3H2,PRKACB,RPS17,ZSCAN25,SLC25A1,RPF2,SUB1,ATF4,RPL7A,GRPEL1,HSPA5,RPS15,WDR3,MRPL40,PGK1,RNF113A,BAP1,RPL27,PML,HEXIM1,ZNF770,RPA2,CFTR,HSP90AB1,RPS10,ISG20L2,LYAR,DRG1,MAGOH,AGR2,XPO1,MRPL9,NGDN,DDRGK1,CTNNB1,DDX50,RIOX2,WWP2,RPL6,RPL28,RPS4X,UTP25,KRAS,TRIM11,RPL31,TOP2B,PABPC1,RPL18,RPS23,GLE1,SMNDC1,SOX2,RPS7,EEF2,TRMT1L,RPL10,MATR3,PSMD4,MRPL13,ZNF189,COP1,ICAM1,RPS26,NSA2,H1-1,RCL1,H1-10,FTSJ3,MRPS25,BTF3,RPL39,MYC,SFN,MRPS7,HNRNPA0,UFL1,STAU1,HSPA8,RFC4,PYM1,RPS28,EIF4B,PIH1D1,PAK2,MAP2K1,RPL27A,MTF1,PAFAH1B1 |
| 1.221e-12 | -27.43 | SSB (small RNA binding exonuclease protection factor La) | protein interactions | 6741 | 440 | 192 | 19454 | 5460 |
ATP5F1A,AR,RPS20,MSN,PTEN,TRIM24,CCNF,EIF2AK2,POP7,CTTN,VIRMA,RPL22,RPL13A,RPP25L,ARMC6,KLF12,CCNA2,RPLP0,METTL14,LSM2,RPA3,SOD1,SIRT7,NHP2,RPL4,HDAC6,GRSF1,CALR,SPP1,PTPN1,KRR1,PRNP,EEF1A1,CCT5,SRP72,RPL23A,HAPSTR1,HSD17B10,TCOF1,GLUL,RPS13,HUWE1,VRK1,TOM1,PRPF31,CUL3,CUL2,RPS5,SP1,ZCRB1,BRCA1,LMNB1,SNRPD2,SNRPD1,SEC61B,TRMT6,FAU,EIF3K,RSRC1,RPL19,SNRPB2,RPL35,ACTB,PRDX3,TRUB1,NUP50,HNRNPA1,HMGA1,PRPF19,HNRNPD,RPLP1,RPLP2,WDR6,PHB1,FBXO32,ZNF593,NOP58,RPL7,CCS,NUP153,RAF1,ANP32A,RPS11,SART3,SNRPE,EZH2,RPS24,ARGLU1,RPS27A,SSRP1,G3BP1,MAT2A,AKT1,RPL7A,SUB1,IGF2BP1,PDCD4,UBE2H,CSNK2B,SRP54,RPS3,ZNF330,SMURF1,BCCIP,CDC42,HEXIM1,UBE2M,KLF4,RNF113A,BAP1,RPL27,BCL6,HSPA5,RPS15,CSNK2A1,COPS5,TSEN34,GAPDH,KARS1,ANKMY2,RPS2,USP15,RPL10A,TRMT5,SNRNP70,RPS16,CAND1,SPPL3,FZR1,RPS27L,ARHGAP12,H2AX,RPSA,TP53,CBX3,RBM34,RPL3,DHX9,MEPCE,RPL17,CAPZA1,H3C1,NEDD8,KPNA2,HNRNPK,RPL39,CASP4,SNRPB,MYC,HNRNPAB,RPS26,H1-1,CCT2,SURF2,ESR2,RPL27A,EIF4B,PPT1,HSPA8,EP300,DDX5,RPS28,RPP14,UFL1,STAU1,ARHGEF39,DDRGK1,IFI16,YWHAB,CCDC71,TRMT61A,HSP90AB1,CCT7,NOB1,RPS10,TCP1,SNRPA1,SNRPD3,SOX2,RPS7,ARFGEF1,ZRANB2,MOB3C,EWSR1,RPL31,CCT8,PABPC1,RPS4X,TFG,HNRNPDL,KRAS,VDAC1 |
| 1.255e-12 | -27.40 | SYNCRIP (synaptotagmin binding cytoplasmic RNA interacting protein) | protein interactions | 10492 | 669 | 271 | 19454 | 5460 |
THUMPD1,PML,BAP1,MIR10B,DLAT,RNF113A,HNRNPH2,MIR107,MIR29A,CAPN1,MIR34B,MAEL,PLP2,AGO1,RPA2,MIR7-1,MIR21,UBE2M,HEXIM1,GCFC2,RPS3,PSPC1,MRPS28,EIF4H,KCTD9,SMURF1,PTPN11,MORF4L1,RC3H2,UBE2H,ELAVL2,IGF2BP1,PTTG1,MIR200A,MIR9-3,DHX9,HNRNPK,NEDD8,MIR16-2,MIRLET7C,MEPCE,TP53,RPSA,IPO8,UBL4A,METTL15,H2AX,DUSP1,DISC1,TFCP2,DDX42,NUPR1,HBP1,MRPL33,CD274,RPS27L,NKAP,MIRLET7G,FZR1,CAND1,MYL12A,MALSU1,RBM42,DKC1,MIR429,COX5A,FAM20C,GAPDH,CD81,COPS5,RPL24,SNRNP70,H2AC4,TSNAX,SNRPA,DDX5,MED13L,HSPA8,STAU1,TMEM177,HNRNPA0,UFL1,DUSP14,KLHL3,GTF2IRD1,SDC2,PAK2,PIH1D1,TRMT112,CNDP2,CMTR1,MIRLET7B,MATR3,RPL10,HNRNPC,HNRNPAB,MYC,SNRPB,BTF3,FBXW11,ELAVL4,ICAM1,MIR9-2,LSM14A,PABPC1,NDUFB5,EWSR1,MIR206,MIR155,KRAS,HNRNPDL,PPIL3,HEXA,TOP3B,MIR222,APTX,ZRANB2,FUBP3,SRSF1,MIR214,EED,SNRPA1,MIR9-1,SUMO2,HNRNPL,PAIP1,HSP90AB1,PNPLA8,MIR143,WWP2,IFI16,DDRGK1,CTNNB1,MIR29C,NDUFV2,CPEB1,MIR31,AGR2,MIR140,MIR221,SIRT7,MIR205,RPA3,SQSTM1,MIR34C,MIRLET7I,FBXW7,MIR7-3,SS18,TXNL4A,SF3A1,RBMS2,MIR1-2,METTL14,MRPS34,MTRES1,RPLP0,PDCL,RPL26L1,METAP2,CTTN,MIR16-1,CCNF,RPS20,TRIM24,SYT2,RTRAF,PRKRA,TXN,NDN,VIRMA,TUFM,DNAJC8,USP14,RACGAP1,RUNX1,STK24,MIR145,IVNS1ABP,YPEL5,PAIP2,RAB1A,FAF1,SNAP23,RPL23A,TRIM63,VRK1,LSM4,SMN1,YTHDF2,FBP1,MIR200C,MIR15A,APOBEC3D,MIR20A,MIR17,ILF2,SLC25A20,HRAS,MIR106B,AIFM1,MIR25,PRR3,MRPL50,TOP1,DCUN1D1,ZBTB2,CDK9,NCBP2,GRSF1,MOV10,HDAC6,PSMD7,MIR34A,CRY1,YTHDF1,GPC1,MIR106A,G3BP2,WDR77,MYH1,LARP4B,UBE2S,BAD,GRIA1,RPS9,ACTB,PRRC2A,MIRLET7D,CUL2,CUL3,USP13,MIR98,DCAF4,BRCA1,MIR363,HNRNPA2B1,TRIP4,HSPD1,UBE3A,ZC3H7A,TRIM37,ZBTB14,G3BP1,TNF,RAD21,SSRP1,RPS27A,UBE2A,B3GNT2,ACTN4,CHMP4C,RPN1,EZH2,MIR7-2,PHB1,MIR141,KCTD10,CSF2,DHX15,STOML2,MAP1S,HMGA1,HNRNPA1,HBA1,SYT4,DICER1,MIR1-1,MRPS26,RB1CC1,HNRNPD |
| 1.265e-12 | -27.40 | PSMA7 (proteasome 20S subunit alpha 7) | protein interactions | 5688 | 243 | 120 | 19454 | 5460 |
PSMA1,KRAS,PSMA2,PSMD12,RBM3,PABPC1,UBE3A,MOB3C,B3GNT2,ERRFI1,ISG15,SOX2,MSX2,EEF2,SNRPA1,PSME2,PSMB5,PPP2CB,PHB1,PSMB4,AGR2,PSMD10,MAPK4,PSMD3,IFI16,DDRGK1,PSMC1,DDI1,SKP1,HSPA8,TXNL1,PSMA3,RMND5B,PSMB7,PIH1D1,PSMB3,PSMD4,PRDX2,PSMD6,PSMB6,ESR2,POMP,PSMD14,ATG3,BRCA1,OXTR,SERPINH1,RIT1,MYC,PSMA4,CUL3,PSMD1,BAG3,HUWE1,PSMA5,SEM1,NEDD8,PSEN1,MEPCE,FKBP8,MAP1B,PSME1,DNAJC2,PSMC3,RAD23B,RNF8,RNF181,INSIG2,MAP2K3,PSMB9,FZR1,PRNP,MDM2,CD274,PSMB1,RB1,PSMG2,NME2,TIAM1,PSMD7,DNAJC7,KARS1,COPS5,DESI1,HMGB1,DVL2,BAP1,RPA3,PRPF4,PSMG4,SYVN1,MAVS,RPA2,LMNA,METTL14,GRM2,UBE2M,HEXIM1,PSMC4,SPTBN1,CFTR,PAAF1,ADRM1,VIRMA,CCNF,PSMA6,PSMC5,GANAB,MRPS16,SPOP,ATP1A1,UBE2H,PSMG3,TNFAIP3,MAT2A,PSMB2,CEP85,FBXO7,AR,USP14 |
| 1.296e-12 | -27.37 | proteasomal protein catabolic process | biological process | GO:0010498 | 384 | 178 | 18204 | 5365 |
FBXW4,PSMC5,PML,HSP90B1,RMND5B,FBXW11,TNFAIP1,UBXN2B,CCNF,RAD23B,RNF10,EDEM2,PSMD14,FBXO3,APPBP2,GID4,TMUB1,KCTD10,FBXO31,PSMA2,KBTBD6,BIRC2,ERLEC1,PSMC4,PSMC1,PSMD4,STUB1,FEM1A,DNAJC10,BFAR,SH3BGRL,DERL2,NSFL1C,ANAPC13,FBXW7,RNF5,PSMD3,PSMA1,RNF139,CUL2,NFE2L2,FBXO7,UBE2H,RBCK1,SIAH1,EDEM3,PSMB9,FAF1,FBXO22,SPSB3,ZNRF1,CCDC47,UFD1,KLHL22,HECTD1,CUL3,COP1,PSMD1,RNF187,TRIM3,MAN1A2,CSNK1A1,SGTA,FBXO44,CDC26,FBXL3,DTL,MDM2,SPOPL,CDC23,PSMB5,RNF121,TRIM45,FBXL14,ADRM1,ZFAND2B,ANAPC16,UBE2D3,TRIP4,PSMB4,ENC1,CRBN,TRIM21,FBXL7,RNF41,DDIT3,FBXL19,EDEM1,USP14,ANAPC11,PRPF19,OS9,PSMD7,SYVN1,PSMA3,GSK3A,DERL1,RNF126,XBP1,SPSB1,PSMB3,SEC61B,TOPORS,PSMC3,SKP1,PSMB1,PLAA,UBE2N,DNAJB9,UBE2D1,UBXN10,TMUB2,RNF103,DCAF11,UBE2W,FEM1C,PSMD12,PSMA5,ZFAND2A,FBXO9,PSMA4,CALR,KLHL15,ARMC8,PSMD6,CTNNB1,GID8,FBXL4,UBE2G2,AKT1,SDF2L1,FEM1B,SIAH2,FAM8A1,DDI1,UBXN6,SELENOS,PSMB6,IFI27,PMAIP1,ERLIN1,ANAPC15,KCTD17,KLHL3,SPOP,PSMB10,HSPA5,SMURF1,PSMB11,WWP1,MAEA,UBE2B,RHOBTB3,HM13,ANAPC2,JKAMP,DNAJB2,TRIM26,PSMB2,ECRG4,UBE2S,MTM1,CDC16,UBE3A,WWP2,ERLIN2,ANAPC4,FAF2,FZR1,CDC20,PSMB7,PSMA6,HECTD3,PPP2CB,RNF122,RNF34,PELI1,UBE2A |
| 1.342e-12 | -27.34 | identical protein binding | molecular function | GO:0042802 | 2043 | 750 | 18094 | 5411 |
TRIM22,TXNRD2,DPY30,RALYL,SYP,ALDH1A3,ACHE,GMDS,ERG28,ESD,SEC13,RIT2,DISC1,VEGFA,HELT,GALE,TOR2A,MCPH1,MPST,LDHB,NAB2,ISCU,ATL1,C1QL2,KARS1,NOG,LZTFL1,ASPA,PLCB1,CRYAB,DEFB1,RRAGA,LTBR,PGR,EWSR1,NACC2,TRIM29,TYW5,MAD2L1,MMUT,CER1,RB1,MMP9,PLN,DESI1,KATNAL1,MX1,CASC3,LRRC8A,ABCG2,NCR3,USP2,GCA,IK,CTSC,CCL5,UAP1,ISCA2,UCK2,CREBZF,MATR3,ATG7,YWHAH,CYBRD1,CASTOR2,CRYBA2,WRAP53,TPD52L1,TAF1D,UBASH3B,TLR6,RNF8,TXNRD1,TNFAIP1,DDX39A,CREB1,NUP153,CRYM,CYP2R1,GSTM3,TRIM3,CGGBP1,DLK2,DCTPP1,BORCS6,VAC14,PRPSAP1,MECP2,GOLGA5,DPAGT1,SSBP1,KCTD11,FGFR1OP2,TNF,GRID1,KCTD10,ACOX1,PRDX3,HAND2,ACCS,DNAL4,CLTRN,TEF,FOXP1,PAFAH1B3,IL6ST,SMAD2,MET,SLC25A14,CEP70,MGST2,FXR2,GTPBP2,MTMR2,FBLN5,STARD3NL,IZUMO1,RAB9B,ACTN4,CST3,RBBP8,AGR2,MLC1,RNF20,S100A10,FKRP,ZNHIT6,CLDN22,NME1,COL1A2,MAP1S,GLIPR2,SPPL3,ST3GAL2,UCP2,TIRAP,GPHN,YWHAB,CLDN9,ATG16L1,CD28,HSP90AA1,LILRB1,SOD1,GGPS1,CRLF3,GNPTG,STAT1,KCTD17,NEFL,PC,DLAT,NPR2,TRIM37,TBK1,SMARCB1,MAP3K12,ADD2,PRKRA,RPE,DYNLL1,PRDX1,RIOX2,ADIPOQ,SLC2A1,GSTA4,TAF10,MAP3K11,NDC80,RCHY1,NOP53,GKAP1,KIT,RABL3,FUT9,PPP5C,DNPH1,GGCT,FCER1G,SP4,HTR2A,STAT2,CAV1,STAT6,KCTD9,PNPO,BRAP,CEBPG,LDHA,BIRC2,STK26,MDFI,PRMT5,ZNF24,CSNK2B,BST2,SDS,EXD2,HEXIM1,CD3G,BMPR1A,HM13,PYCR1,BNIP3L,USP15,RNF41,SERPINC1,CREB3,MIF,BRCA1,MYD88,TNPO3,TNFSF10,ZBTB26,CD2,CLDN12,CRMP1,FHIT,AQP3,JUP,ASMT,C1QTNF1,SAV1,GSTM2,MBL2,IL17F,TXN,HDAC5,CBX3,CEP85,CDSN,AGER,HTRA1,PRDX4,SYNDIG1,ADIPOR1,SMAD1,CCL3,STXBP1,MAVS,CUL3,DCK,CACYBP,RNF40,MVD,SCHIP1,GPX3,EMILIN3,ZCCHC17,FIBIN,CPNE1,NQO1,ST6GAL1,PHETA2,CDH13,LEPROTL1,GFUS,MYC,XPNPEP1,FOXC2,CTBP1,ANXA4,RNF5,TWNK,CCR2,SLC39A13,GNPDA2,UGP2,SMAD4,S100A6,CRYBA4,VSIR,HSPB8,DERL1,MAPRE1,WTAP,CAMK2G,MSH6,YWHAG,NFE2L1,PHB2,PNMA5,F11R,HEXB,EIF2AK2,IRF3,SLC51A,TFRC,CLDN8,TUBG1,NFKBIA,RUVBL2,LY6G6C,TPPP,PLPP4,S100B,KCTD15,RPIA,GSTM5,APOBEC3F,SHMT1,FBXW7,ATF1,PDIA3,HNRNPC,CSK,BRI3,PAFAH1B1,GAPDH,RPL22,B2M,GREM1,TNFSF18,SFTPC,BCL10,TIMM8A,CDC5L,ZBED1,THAP7,EED,SSNA1,CAV2,LNX2,AOX1,STK3,CITED1,AKT1,SDC2,TLR3,TRIM23,BMP1,PSME2,PRPS1,EXOSC8,CHMP1B,NFKB1,LDLR,BEX3,PIP4K2C,STUB1,SELENOK,OXSR1,KCNJ2,FATE1,ENO1,ZBED4,DNTTIP1,DHRS4,SMG9,APOBEC3G,SH3BP4,CSNK2A1,TRIM34,CGAS,OIP5,JAK2,PRPF31,TTR,MAFG,MAX,FOXP2,PRDX6,TRAF1,TRIM68,MAT2A,DPP4,TYROBP,DYNLT3,BHLHE40,SNX33,EPHA4,S100A11,CHRNA7,BECN1,ABCB9,CLDN4,GNPDA1,SMAD3,SAT1,PGRMC1,FAM161A,GRAMD2B,CLDN6,SLC4A8,RILPL2,GSTM4,TGFB2,BAK1,PHF1,DDIT3,UGT1A1,C1QL3,LYZ,NIF3L1,PCBD1,MAP3K21,DYRK1A,PIK3AP1,CARS1,GPRASP3,AHCYL1,NMRAL1,BCL6,NFE2,FOS,PDE2A,G6PD,GLE1,SLC31A1,NHERF1,GRPEL1,HSP90AB1,SNX2,SMN1,NLRP3,PRPF19,ALOX5AP,TOPBP1,SAT2,TLR4,TIMM10,DAPK1,SOD2,FAS,STK4,ADD1,PAFAH1B2,HNF1B,DES,ALB,ODC1,ZDHHC17,SERPINA1,ATF4,CLDN11,FBP2,LY6G5C,CEACAM5,TRIM62,GHR,UBE2G2,STX1A,PDCD10,PML,FGFR1,MCOLN1,CDH8,SFRP1,ZNF174,FABP5,DDX39B,MRFAP1L1,ADRB3,GLCE,SLC25A12,LDB1,NELL2,ZBTB38,TP53,SLC6A1,SRM,NR0B1,HAS3,DRG1,FCHO2,HADH,PIK3CG,EID2B,PSMD4,FOXP3,TENM3,DGCR8,ALCAM,CD79B,NONO,SLC22A6,FTL,NDE1,SLC16A1,UBA3,NAA60,FAM83A,GSTO2,STIM1,MFN1,SFN,MIEF1,TMEM14B,COIL,ATF3,TLR1,TLR9,GRIA1,JAML,SDCBP,TMCC1,OPTN,SH3GLB1,AMELX,ADRB2,GRPEL2,CEBPE,MAPRE2,IFIH1,ANGPT1,SIAH1,PCDHB8,IGF1R,RPRD1B,HPGDS,PRMT2,NPC1L1,MMACHC,PHYKPL,RGMB,DRAP1,CLDN1,PRNP,GID8,PYCARD,JCHAIN,PADI2,NTRK2,PTEN,TMEM38B,CBX5,IFI35,CHMP4C,MID1IP1,KLHL7,EXT1,SQSTM1,RPL7,SH3GLB2,SNRPA,KLHL12,IDE,IKBKB,EMILIN1,ESYT1,DVL2,CIB2,HNRNPK,GPX4,OLR1,TOR1B,BANF1,GTF2A2,TMIGD1,DAAM1,TSG101,CD38,EIF3J,ATG101,BOK,BCL2L1,STC1,CLEC2B,RRM1,NLGN1,CRYL1,CD2AP,BIRC5,ATP5IF1,TRIM8,CDC42,NFIL3,HSPB1,GJB2,TPST1,VPS4B,ACAT1,IDH1,TNFAIP3,TESC,PNP,TRIM21,CRKL,FIS1,TYMS,HSBP1,LRP6,HSCB,LYAR,JUN,GADD45A,LECT2,TP53I3,SAMHD1,HMG20A,HMGCS1,SMCHD1,RIGI,MGST3,ACACA,CISD1,PAK2,PSMD7,DCTD,DHPS,EDC3,ILDR1,TRAF2,ERP29,NT5C2,CD226,GIMAP2,KDM1A,HSD11B1,CBLL1,STAC3,EHD1,TRA2B,PICK1,PBLD,IL12B,PPARG,RAF1,SEPHS1,CD247,SFTPD,FLRT3,QTRT2,VDAC1,CIDEB,DROSHA,XCL1,NECTIN2,NUDT5,SUB1,FZD4,NKAPD1,PDLIM4,FRS3,PAXX,EMG1,NUP35,APEH,VSTM2A,MKLN1,CAP2,VWF,CDR2L,RTRAF,RBCK1,TMEM115,MME,SEPTIN7,MSTN,GNPNAT1,HSD17B1,TLE1,BAX,NDP,CHMP1A,MMAA,NLGN2,OAT,TLR2,HOMER3,SORD,TNFAIP8L1,HTRA2,HINT3,RABAC1,TERT,IMPA2,NUDT16,MGAT4A,BOLL,CEP57L1,SDC4,CLDN14,GABRB3,BAG2,MORC2,ACVR1,ADIPOR2,MDM2,TSN,GLTP,RAG1,XBP1,FTH1,TLR10,PSMC3,CCDC92,CNR1,FBP1,DAPK3,IAH1,VAPB,SNX1,HEY2,SLC25A27,TRIM5,MCM6,STOM,TUBA1A,CTNNA1,LITAF,CRYBB2,TRIM6,TRAF6,SLC6A4,TLNRD1,GLUL,NOL12,MUL1,MAPK4,PCNA,FKBP8,ACADSB,TGFB3,SLC1A1,IFI27,CLDN3,CD4,HEXIM2,CBLN1,GNMT,TMEM266,NMI,GJB1,ACTB,ZBTB16,GREM2,KCTD12,FAM118B,HPCA,ZBTB2,TFG,CRYZ,TRIM32,TRIM27,RHCG,SP1,PACSIN3,TMX2,UGDH,PTS,YWHAZ,ZHX3,SGTA,THG1L,TPD52,THAP1,CCR5,MNS1,HSPB6 |
| 1.375e-12 | -27.31 | PPP1CC (protein phosphatase 1 catalytic subunit gamma) | protein interactions | 5501 | 708 | 284 | 19454 | 5460 |
PSME1,ABCE1,RPL3,MRPS18B,KPNA2,PDRG1,CAPZA1,RPL17,RRM1,TP53,RPSA,WBP11,UBXN2B,RPAP2,RBM34,CAPZA2,BMPR2,NEFL,BIRC5,NUPR1,PHC1,SFRP1,RPL32,GATAD1,PNMA3,TMPO,ZNF24,RBM17,COPS5,TPM3,SNRNP70,RPL24,H2AC4,RPS2,CDK12,RPL10A,LIN7C,BTBD10,RPL27,BANF1,RPS15,HSPA5,SPTBN1,PPP1R8,NEK2,RPRD1B,RPA2,ZNF326,LUC7L3,RPS3,PSPC1,CSNK2B,RPGRIP1L,PPP1R10,DYRK1A,PPP1R1B,AKT1,RPL7A,CCNB1,RPS17,ARHGAP21,RC3H2,IGF2BP1,UBE2H,RPL31,PABPC1,RPAP3,MYO1B,RUVBL2,KRAS,RUVBL1,RPL28,SECISBP2L,RPS4X,CBLL1,MAX,RPS7,SMARCB1,RPL18,RPS23,KCTD20,SRSF1,GYS1,CORO1C,WDR82,CSRNP1,RPS10,HNRNPL,SUMO2,TAX1BP3,RPL6,VSTM4,DDRGK1,PPP1R11,YWHAB,SNRPA,SPECC1L,RPS28,HSPA8,DDX5,EP300,SRSF2,TRA2B,UFL1,STAU1,CHRNA7,SAP18,RPL27A,CD59,PIH1D1,CSNK1A1,NCOA5,PHF12,FAM83B,ATP5F1B,SNRNP40,POLR2B,PPP1R3C,ESR2,RPL10,APOBEC3B,MYC,CREBBP,HNRNPC,RUSC2,CCDC85B,KIAA1191,CCT2,CKB,FBXW11,CHTOP,FTSJ3,TEX36,RPS26,PPP1R12A,PQBP1,DLG1,NKRF,RPL23A,THRAP3,DNAAF10,RPS13,RIGI,CD2BP2,MAP1LC3B,LBR,RPL15,TBC1D19,CASK,RPL12,RB1,PPP1R18,TOP1,ASNSD1,HDAC6,LAMP3,TOPBP1,RPA3,SIRT7,PPP1R2,FBXW7,RPL4,PIAS1,NHP2,BRIX1,ATG16L1,RPS14,CCND1,TOX4,CDK1,LMNA,HNRNPH3,WTAP,SHOC2,CCNF,EIF4A3,EIF2AK2,TRIM27,GSK3A,RPS12,RPS20,TXN,TMOD3,RPL13A,RPL22,VIRMA,RPL26,NONO,KPNA6,PPP1CC,USP14,CDC73,AP2A1,COL1A2,HNRNPA2B1,PCNA,SRSF7,COX8A,RPS24,BAG2,RBBP7,TRIM37,RPS27A,SRSF4,ENKD1,GOLGA7,SSRP1,CSNK1E,RAF1,VDR,NUP153,RPL29,WDR37,EZH2,RPS11,SF3B5,POLR2C,RPL9,RPL8,RPLP2,HP1BP3,RPLP1,RPL7,EGLN3,SRSF10,DIRAS3,NUP35,DHX15,NUF2,BABAM1,DPY30,NDC80,INSYN1,TRA2A,SIAH2,FXYD6,RHOG,SKIC8,TRAF6,RASSF8,CAMSAP2,BCL2L1,RPL23,GRXCR1,HTR1A,NMRAL1,NUP50,NSFL1C,SKP1,FTL,CCND3,H1-5,PPP1CB,IFTAP,MYL6,FAU,ENO2,LRRC1,POLR3B,SNRPD2,RPL37A,RPS9,ACTB,RPL35,TUBB,ERH,B4GAT1,GNB1,RPL19,JAK2,DSN1,CUL3,GSTM5,HSD17B3,RIOK2,RPS29,PPP1R16A,YWHAZ,MYO6,BRCA1,RPS5,PFDN2,VMP1,PFDN6 |
| 1.417e-12 | -27.28 | positive regulation of cell communication | biological process | GO:0010647 | 1792 | 659 | 18204 | 5365 |
ILK,CASP4,FBXW11,LGI1,GPR89A,NPY5R,ADNP,CITED1,VAMP2,RELL1,LSM14A,SPHK2,ZNF622,TIFA,CCR2,F2,CSNK2B,CTSD,CFTR,PRKCA,GJA1,DDR1,NLRP3,ACVR1,AVPR1B,TESPA1,SEC13,MIR145,CX3CR1,TRAF2,MSX1,LRRTM2,VAMP7,RUVBL1,PDIA3,EDA2R,LY96,TRIM6,RPS3,PHB1,MAP3K11,TWSG1,FGF3,FGF17,ADIPOQ,TNF,CRLF3,SLC39A10,RAF1,CX3CL1,RBPJ,ROCK2,IL10,MUL1,TBC1D24,TMEM198,CXCR4,MIR23A,PYCARD,HRAS,AGER,LURAP1,CD226,PLEKHF1,MAPRE2,HMGB1,FGF7,MME,CXXC5,KLK6,HFE,PTK7,STX1A,FAF1,RPS20,IL7,ATAT1,EZH2,MIR198,CHRNA7,OSBPL8,HINT1,C1QTNF1,TPBG,EPO,S100B,IL34,IKBKB,RBCK1,TGFB1I1,GAPDH,CYP27B1,TRIM44,SIAH1,TRIM15,LIPA,MIR212,PPARG,CLSTN3,CCDC22,CSNK1A1,F10,SRARP,RPL23,SFRP4,KLHL22,F11R,TRIM52,PDE9A,PPP2R1A,SESN2,JUP,RELL2,GPNMB,IRAK4,ZNHIT1,TNFAIP8L3,MIR1-1,CLEC7A,AVPI1,MAP3K3,DDX5,NEK7,SDCBP,RRAGA,TNFSF10,LPAR1,STK4,FKBP8,CTSC,SPPL3,TP53,HOMER1,ZBED3,NETO1,PTPN11,PIP4P1,CRBN,DLG4,DDIT3,LRRC8A,RPS15,TLR4,P2RY1,FGFR1,TMEM33,ITGAV,GABBR1,ACKR3,MIR26B,PRDX2,GHR,ADORA1,LARGE1,FGF22,PTPN1,LAMB2,PAGR1,CHGA,SHC1,CCR1,PRKCB,MAP2K1,NUCKS1,RAP1B,IGFBP4,IL5,SLC38A9,MAD2L1,FKBP1A,NLRP6,IRF7,TLR7,ACTN4,MIR1260B,PELO,ING5,CAV2,TMOD2,RIT2,DHX15,IFI35,BECN1,LTBR,FIS1,LITAF,PICALM,ADAMTS20,HCST,TRIM22,PROK1,CSNK2A1,GHRL,MIR20A,CCL21,TNR,CTNNA1,NDFIP1,CBL,ANKRD6,SOX9,RHEB,LTB,GKAP1,FGF10,RAB29,SPRED2,NCK1,TRIM8,MBD5,KRAS,NOTCH2,MIR346,RIMS4,ACTA2,MAP2K3,IL1A,TGFB2,OSBP,SEMA5A,CDH13,CCR7,CREBBP,PROX1,RNF167,ENHO,HAND2,MTDH,ADRB2,GREM1,GAS8,CA8,COL3A1,PDE8A,SOX2,PTPN22,DKK1,VAMP8,SPP1,PIM2,CD28,MYORG,HSP90AB1,LANCL2,MEF2C,GPR35,CDKN2AIP,ING2,STAMBPL1,EEF1E1,DOK4,SLC20A1,IFNB1,CAV1,MAVS,GPBAR1,TAB1,TNKS,DEPDC1B,RC3H2,CSNK1G3,TMEM101,USP8,MIR324,FAM83B,IGFBP3,TRIM26,ATP2C1,HBEGF,CD4,CD81,MIR146A,TNKS2,ARL6IP5,HTRA2,GFI1,MYD88,MIR342,MIR421,SMAD2,TACR1,GADD45B,NPTN,IL4,CSNK1E,IFT172,FERMT2,MYC,SFRP1,FLCN,IGF1R,MIR126,CREB1,GPR17,CDC42,PPIA,DUSP19,NUPR1,CCL5,AKAP12,RIMS3,TLR3,TRIM68,SOS2,DOK6,HCRT,IL6ST,MAP3K12,IRF3,USP15,OPRM1,SNAP25,STK3,RASL10B,CCL3,MIF,DDT,HTR2A,BCL10,TEDC2,TPD52L1,ATP6AP2,RWDD3,CRADD,DRD1,PIH1D1,TERT,CHRM3,MIR16-1,NFKB1,IGSF11,SRI,GNA11,NHERF1,TASL,NPSR1,BMPR1B,NPPC,MAP2K6,CCL2,DISC1,CHI3L1,HCLS1,NUP62,PML,JMJD8,SYBU,WBP2,GRM2,C2CD2L,DIRAS1,CCL19,TBK1,NINJ1,MIR181D,CD38,LAMTOR1,GSKIP,NLGN2,GADD45A,TRAF6,MIR183,TLR2,CYP1B1,NDP,TICAM2,TRIM32,CCN3,RAP1A,PIK3AP1,TMEM108,TRIM62,LACRT,BIRC2,TFRC,ALKAL1,SMAD3,MIR24-1,CD63,DUSP22,ATF3,RGL2,FBXW7,NKX3-1,HDAC6,ZDHHC17,FCGR2B,RPS7,NOG,S100A8,PRR5L,STK11,CCAR2,SELENOT,ADIPOR1,STAP1,TRIM5,FGF16,SYK,ACVR1B,RALB,CD40,ADGRG1,BMPR2,IL23A,SEMA7A,VEGFA,MIR29A,LAMTOR2,PRRT1,AKR1C2,RPS12,TLR1,TICAM1,FGF23,BMPR1A,MECP2,SMARCB1,NDC80,PPM1B,FABP5,MIR296,OPRK1,NTRK3,LMO3,NTRK2,SHOC2,RXFP2,PIK3R1,NR2E1,ZNRF1,CUL3,TRIM3,OSM,AFAP1L2,LYPD6,P2RY12,ROCK1,RAB8B,PDCD4,PDCL,STAU1,PRKRA,NEO1,MIR15A,LGR4,BIRC5,NLE1,PAFAH1B1,DYNLL1,GPR37,F7,PIK3CA,RNF146,ICAM1,SERINC3,TAB2,DOK5,NLGN1,TCIM,PHB2,HEXIM1,SCHIP1,PIK3CG,NECTIN2,TRIM21,MIR140,LEP,FASLG,SQSTM1,TNFSF12,LAMTOR3,CSH1,IL18,RB1CC1,SRC,ADRA1A,ANGPT1,RAMP3,DVL2,CDK5RAP3,GLCE,MIR545,GSK3A,PRKCE,BAD,SLC4A8,G0S2,MIR10B,TFG,PPP3R2,LIMS2,PTEN,JAK2,PPP5C,P2RY10,STXBP1,IRAK1BP1,TTI2,FGF1,BST2,PLA2G5,TIRAP,NRP1,ARRDC3,MIRLET7B,TGFBR2,MIR221,PAK2,AR,SOD1,DIRAS2,CARTPT,UBE2N,CRKL,XBP1,TSPAN5,ADRB3,MIR320A,GRIA1,CD14,EIF2AK2,FAS,GNAI2,KIT,SLC1A1,CTNNB1,TNFAIP3,GH1,CTSK,GID8,HYAL2,VDR,TXN,BAK1,MIR95,TMEM106A,MT3,KLK5,GPX1,RALA,RETN,CYFIP2,OXTR,EP300,SNX5,LPAR6,IGF1,CIBAR1,SPRED1,PDCD10,MIR675,CALR,BOK,PRMT5,AGR2,TLR6,TMED4,RPL26,PFKFB2,GRB10,SMAD4,ITGA2,DRD3,MIR182,UBE2V1,WNT7A,PPP3CA,FAM53B,MIOS,AKT1,TGFB3,IL1B,LPAR2,PMAIP1,UCN,MIR210,CD36,CD80,GPR65,CLEC6A,TTC23,EDNRA,NMI,RRAGB,VAV2,DSTYK,WNT10B,CPNE1,NACC2,MSX2,SEMA4C,CDC73,TNIK,CACNG3,INHA,MIR30B,FGFBP1,MIR21,MIR96,VWF,MIR519D,TLR9,PLCB1,PCK2,ILDR1,RTN4,HDAC3,EMP2,ELAPOR2,OCIAD2,MCL1,GLIPR2,UBE2B,TRAF3IP2,BAX,ERP29,NDST1,RSAD2,AGPAT1,IL6,PTP4A3,ASPM,CD86,MMP9,BGLAP,GADD45G,UBB,FOXP1,ACSL4,PEA15,DNAJC27,TMEM100,LRRTM1,FGR,UBE2K,DDX1,UBE3A,IL12B,GRM1,MIR10A,HAX1,ADRB1,NEUROD2,MIR449A,FLOT1,GPR137,PELI1,DAPK3,GPR37L1,OR2AT4,SLC1A3,TRAF7,TRIM34,PRL,MIR186,AKT3,CA2,MIR1224 |
| 1.423e-12 | -27.28 | ATP5F1C (ATP synthase F1 subunit gamma) | protein interactions | 509 | 390 | 174 | 19454 | 5460 |
IGF1R,HAPSTR1,SFXN1,RIGI,HUWE1,AURKAIP1,SERPINA1,NDUFS3,AIFM1,MSMO1,CDK9,ATP5PD,ARF6,HDAC6,ATP5MG,LAMTOR2,CALR,EI24,P2RY1,RTN4,VIPR1,PNO1,RPA3,CHMP2B,PIAS1,FBXW7,PDHB,CERS2,CDK7,UQCRC1,ATG16L1,COQ8B,MET,GRM2,HSP90B1,GOLGA5,ADGRL3,PTEN,SCAMP2,CCNF,VIRMA,UQCRQ,TECR,RHOJ,MGST3,FBXO7,ATP5F1A,ATP5MC1,COX8A,ZC3H7A,OPA3,NDUFA4,TRIP4,HSPD1,ATP5F1D,ETFA,TNF,RAF1,RPN1,EZH2,GATD3,ATP6V1A,PHB1,OPRL1,EGLN3,NDUFS8,MPP1,PTPN5,SAV1,RB1CC1,MED4,AHSA1,RHOG,HADHA,SLC35F2,ATP5F1E,ATP5IF1,ASB3,CCND3,POLA2,COIL,PTN,CA12,ATP5PO,CYB5R3,ARF1,NDUFAF4,ACTB,LGALS3,TOMM40,RAB11A,CUL3,KDSR,MTG2,FMC1,RIT1,HSP90AA1,ARHGAP19,ATP5PF,MAP1B,LPCAT3,MTCH2,ATP5PB,PREB,RNF8,SURF4,COX4I1,SSBP1,MYL12A,LMAN1,EPHB6,COX5A,DPP4,TUBG1,RAB9A,RNF113A,ELOF1,MAIP1,TOMM20,CDC42,CYC1,HECTD1,HEXIM1,GPR35,SSR1,SPRYD4,RPA2,PTPMT1,EIF2S2,UQCRC2,SLC25A1,UBE2H,ATP1A1,TMEM87A,VDAC1,KRAS,CHCHD2,TUBA1A,SOX2,NDUFA12,PDHA1,PTRH2,CORO1C,COX14,CCT7,HSP90AB1,DDRGK1,CTNNB1,PEX3,AGR2,FAM241B,BMPR1A,CERS6,PHB2,ADRB2,STAU1,UFL1,NDUFS2,CD59,SEC62,SLC19A2,BET1,PAFAH1B1,TOMM22,CSNK1A1,RETREG3,DLST,VDAC2,ESR2,ATP5F1B,PCCB,BTF3,MYC,SLC38A1 |
| 1.433e-12 | -27.27 | NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3) | protein interactions | 4722 | 365 | 165 | 19454 | 5460 |
EMC2,SLC16A1,CLPB,ATP5PF,SFXN1,PSMB10,FASTKD5,MRPL22,RASL10B,DNAJC30,HUWE1,METTL15,AURKAIP1,APOO,GLRX5,NDUFA2,MTCH2,MRPL11,ATP5PB,RNF8,GFM2,NDUFS3,ACOT13,NDUFA1,COX4I1,NDUFB4,SSBP1,COQ8A,AIFM1,SLC25A12,ILVBL,ATP5PD,MYL12A,FZR1,ATP1B1,LAMTOR2,COX5A,EMC4,GRSF1,MOV10,CALR,TMEM70,CHCHD1,TMEM11,POR,TMEM126B,GFM1,SQSTM1,SYVN1,RPA3,MAIP1,CRYZ,POLDIP2,SLC25A51,PDHB,CDK7,NDUFAB1,CDC42,UQCRC1,TIMMDC1,MTRES1,CYC1,SAMM50,HSP90B1,RPA2,COX6C,PTPMT1,CCNF,MRPL53,UQCRC2,VIRMA,UQCRQ,CPT2,MGST3,TUFM,HMOX2,NONO,NDUFB10,DNAJC19,UBE2H,ATP1B3,COX8A,HINT2,NDUFA4,NDUFB5,HSPD1,IMMP2L,CDK20,VDAC1,ETFA,CHCHD2,EMC8,EEF2,SOX2,RAF1,MOB3C,NDUFA12,NDUFS6,PDHA1,GLE1,ATP6V1A,GATD3,CORO1C,MTHFS,PHB1,COX14,RMND1,NDUFS8,EGLN3,UQCRH,RHOH,HNRNPL,NDUFV2,STOML2,MTRF1,CLPX,NDUFB8,ARMC8,POU5F1,MRPS26,RHOG,HADHA,CRY1,EXD2,NGRN,ADRB2,OXCT1,PHB2,HSCB,NDUFS2,NDUFAF3,TIMM29,DHRS4,TOMM22,NDUFA5,CSNK1A1,ARMCX3,PPT1,ATP5PO,MRPL13,CCDC90B,MTG1,CYB5R3,VDAC2,TACO1,LMBR1L,PARL,ESR2,NDUFAF4,ACTB,DTD2,ATP5F1B,PCCB,MRPL16,TOMM40,PMPCA,CUL3,NDUFB6,NDUFB7,MTG2,MYC,AUH,ILK,CBR3,HTRA2 |
| 1.523e-12 | -27.21 | RECQL (RecQ like helicase) | protein interactions | 5965 | 278 | 133 | 19454 | 5460 |
MYO6,CYP1A1,CHTOP,RBM27,BRCA1,RPS5,PRSS1,NSA2,DNAJB6,THOC6,MYC,LDHB,TXNRD2,SNRPB,FBXO22,CBX5,RPL19,RABIF,PIH1D1,ACTL6A,PGRMC1,CD59,STAU1,XRCC5,HSPA8,SKIC8,PDIA3,UTP6,RPL7,TCP1,CCT7,WIF1,RPL9,CBFB,TRAF3IP3,FBXO32,PLS3,TUBB4B,SCHIP1,SMNDC1,RBPJ,FEN1,TRMT1L,MAX,E2F4,NUP153,KIF2A,DHX16,PRPS1,HNRNPDL,RUVBL2,RTCB,CDC73,EXOSC1,UBE2H,CSK,PSMB2,GSTK1,MTPN,RUNX1,ATP5F1A,AR,GRPEL2,RPL22,RSL24D1,VIRMA,PELP1,CREB1,OPTN,POP7,PSMC5,RBMX2,RPA2,HSP90B1,LUC7L3,WTAP,RPS14,WDR83,GTF2H4,SEC22B,TPT1,SNRNP27,PDHB,RBM22,RPL4,NHP2,DDX46,BAP1,RPL27,RPA3,BANF1,PML,SIRT7,HNRNPH2,PPIH,TCEA1,SPCS2,RPL24,RPS2,RPL10A,HP,API5,RPL35A,THOC1,TMPO,CDK9,MDM2,DKC1,SYNCRIP,KRR1,DDX42,NDUFS3,NUPR1,CENPM,MRPL11,TP53,DDX39A,EXOSC8,H3C1,PAK1IP1,CTNNBL1,SRPRB,KPNA2,MSH6,MDC1,PPP1R12A,NOSIP,SFXN1,SLC25A11,TCOF1,ZC3H11A,HSD17B10,SNAP23 |
| 1.571e-12 | -27.18 | SAMM50 (SAMM50 sorting and assembly machinery component) | protein interactions | 25813 | 197 | 102 | 19454 | 5460 |
SFXN1,CLPB,LRRN4CL,DNAAF10,DNAJC30,PDE2A,FKBP8,MTCH2,CCT5,MRPL11,MAP1LC3B,APOO,MGARP,NDUFS3,NEFL,SSBP1,AIFM1,COX4I1,TRAK2,SLC25A17,TMPO,DUOXA2,SLC25A12,PLGRKT,MOV10,EDEM1,SLC25A46,HM13,MFN1,SLC2A1,DNAJC7,RPA3,SQSTM1,MAVS,HDAC3,SLC25A51,GABARAP,TIMMDC1,FAXC,RPA2,WRAP53,SLC22A8,PDCL,CYC1,CHCHD6,CDC20,PDCD5,DTL,UBE2H,NDUFA4,SLC2A8,RPAP3,MRPS11,KRAS,VDAC1,PFDN1,IMMP2L,RNF26,B3GNT2,NUDCD3,AQP3,SMARCB1,RPS23,WDR6,MAP1LC3A,HNRNPL,TCP1,NDUFS8,CACYBP,EGLN3,RMND1,COX14,CCT7,PFDN5,FKBP4,AGR2,NDUFB8,TXNL1,HSPA8,AKAP1,UFL1,TOMM22,MTX2,DUSP22,TIMM29,LMBR1L,S1PR4,CCDC90B,RETREG3,SERINC1,MTM1,CHCHD3,PARL,ESR2,GNB1,MYC,TOMM40,CCT2,PFDN4,FIS1,HTRA2,VMP1 |
| 1.688e-12 | -27.11 | SEC22B (SEC22 homolog B, vesicle trafficking protein) | protein interactions | 9554 | 349 | 159 | 19454 | 5460 |
MYC,TM4SF19,RAB11A,BTF3,ATP1A3,LMNB1,RHOB,FCER1G,FIS1,SCFD1,SERPINH1,LMBR1L,TACO1,CYB5R3,RMDN3,TMEM229B,SEC61B,TAX1BP1,REEP4,ATP6AP2,ESR2,FAM234A,BET1,GOSR2,SEC62,OTULINL,RND2,DUSP22,VAPB,UBAC2,JAGN1,PMAIP1,BET1L,RAB5A,IL1B,GOSR1,ADRB2,RER1,STX7,PXMP2,DNAJC22,CERS6,LAMP2,FAM174A,RAB5C,DDRGK1,RHOG,SKIC8,PEDS1,RB1CC1,TST,VPS4A,STX1A,HAX1,DICER1,RAB35,SIN3A,ARL11,MFSD5,GJA1,STX5,CYB5A,LHFPL1,RHOH,EGLN3,TLCD4,PPP2R1A,DNAJC25,TULP3,RPN1,VAMP2,EZH2,STIM1,PDHA1,STX12,SERPINA5,CYP2C9,ZYX,RINT1,TMT1A,SLC39A3,KRAS,SAR1B,NDUFAF2,MGST2,RAB2A,CREB3,VAMP5,GORASP2,DNAJC5,NAPA,CREB1,CCNF,ELOVL4,CALML5,STX10,MGST3,RHOJ,SUCLG2,SEC63,VIRMA,CDC42,ST7,CFTR,PTP4A2,RPA2,LMNA,STX17,FGFR1,METTL14,SSR1,USE1,UBE2M,CLRN1,RPA3,PML,DERL1,RAB9A,RTN4,NAPG,TMEM167B,DPP4,ADIPOR2,EMC4,SLC25A46,COPS5,LAMP3,ESYT1,DNAJC7,HRAS,PTPN1,ARL10,HSD17B11,RAC2,ARF6,TMED9,VTI1B,DNAJC1,MIF,FNDC9,STX6,TMPO,LMAN1,AIG1,CCDC47,UBL4A,SNAP29,RELL2,TAF2,STX8,TCOF1,STX18,MRPS18B,EMC2,IGF1R,RAB3B,MRPL22,MPST,FKBP8 |
| 1.741e-12 | -27.08 | EIF4A3 (eukaryotic translation initiation factor 4A3) | protein interactions | 9775 | 467 | 201 | 19454 | 5460 |
RB1CC1,PPM1B,TRA2A,HNRNPA1,PRPF19,PRDX1,DHX15,SRSF10,PPIA,CCAR2,SPTAN1,RPL7,ATP6V1A,PHB1,THOC2,RPL8,RPS11,CHMP4C,EZH2,ANP32A,SSRP1,SRSF4,UBE2A,SRSF7,RPS24,JAK1,SLC25A5,SCYL2,RIT1,FYTTD1,CUL3,HNF1B,ACO2,SNRPB2,ERH,MAD2L2,RPL19,ACTB,TSN,EIF4A2,RPS9,SNRPD1,SNRPD2,VRTN,RPL37A,RAN,MFAP1,H2AC1,WDR77,UNC45A,UCHL3,NKAPD1,UPF3B,EMC4,CWC15,NCBP2,AKAP17A,IL18,THOC1,TOP1,SEC23A,MYBL2,SRP14,RAD23B,ILF2,POLR2G,RPL15,EEF1A1,LBR,MAP1LC3B,MDC1,CTNND1,THRAP3,HUWE1,HSD17B10,IGF1R,MAPRE1,CASC3,PPP1CC,RPL26,STK38L,SNX3,RPL13A,MAGOHB,NDN,TRIM24,TRIM27,SNX12,EIF4A3,CCNF,H2AC7,GRM2,TPT1,SF3A1,FBXW7,RPL4,HMGB1,SOD1,RPA3,MAGOH,AGR2,DRG2,DDRGK1,CTNNB1,RPL6,WWP2,SNRPD3,HNRNPL,EED,SRSF1,RPL18,SMARCB1,SOX2,SUPT5H,POLDIP3,RPL28,CDCA7L,PSMA1,KRAS,HNRNPF,PICK1,RPL31,CHTOP,SNRPB,HNRNPC,MYC,RPL10,ESR2,SNRNP40,MATR3,PRMT5,CMTR1,DLST,PIH1D1,EIF4B,ADSS2,ZC3H14,RPL27A,NUP62,SAP18,STAU1,TRA2B,SRSF2,HNRNPA0,UFL1,DDX5,HDAC5,SF3B1,HSPA8,CNKSR3,SNRPA,SLU7,PYM1,DDX39B,RPS2,SNRNP70,RPL24,SMAD4,API5,CDC5L,TMPO,FZR1,RPS16,CAND1,VTI1B,ALYREF,NUPR1,DISC1,IK,TFRC,CAPZA1,RPL17,HNRNPK,CDC40,ABCE1,RPL3,TCEA2,ZNF451,MAP1B,SNIP1,UBE2H,PDCD4,CCDC174,RC3H2,NIF3L1,RPL7A,SUGP1,SMARCA5,SRPK2,GCFC2,PSPC1,HEXIM1,HBB,WWP1,RPA2,AGO1,SPTBN1,DDIT4L,RBM22,STK38,HNRNPH2 |
| 1.744e-12 | -27.08 | PSMD1 (proteasome 26S subunit, non-ATPase 1) | protein interactions | 5707 | 416 | 183 | 19454 | 5460 |
RHOB,BRCA1,HSP90AA1,ALDH1L1,CUL3,MRPL16,MTM1,VPS72,PELO,PSMB7,MFAP1,RND2,MRPL57,PSMC1,RNF11,PXMP2,TXNL1,PSMA3,SKIC8,TRAF6,PSMD10,DCAF11,VPS4A,RPL23,PSMD3,MARCHF5,HNRNPA1,EGLN3,DIRAS3,PSMB5,PSMB4,EZH2,RBM12,PPP2R1A,RBBP7,CDK20,RPS27A,PPWD1,PSMD12,RPS24,UBE3A,FBXO7,ATP5F1A,AR,RACGAP1,USP14,RHOJ,VIRMA,STUB1,CCNF,TUBA1B,GSK3A,RPS12,RPS20,CDK1,METTL14,SNAI2,GRM2,PSMC4,SF3A1,UBLCP1,SMC4,MBD3,SIRT7,SYVN1,PSMD7,ECD,MOV10,HDAC6,PRNP,MDM2,AIFM1,PSMB1,ZFAND2A,RAD23B,EEF1A1,PSMB9,SMAD1,HUWE1,CTNNBL1,SEM1,MRPL22,VTA1,HAPSTR1,TGIF2,HSD17B10,EMC2,PSMD14,MRPS25,MYC,PSMA4,PSMD1,PSMD4,PSMD6,PSMB6,ESR2,LMBR1L,PRMT5,PHF21A,KLC2,PIH1D1,PSMB3,EDEM3,EMC1,UFL1,EYA3,STAU1,EEF1G,DDI1,SAP18,RPS28,HDAC5,HSPA8,EP300,AGR2,HSPB1,XPO1,YWHAG,CTNNB1,HNRNPL,DYNC1I2,RHOH,HSP90AB1,PSME2,RND3,MOB3C,RHOBTB1,TUBA1A,ISG15,H1-3,MSX2,KRAS,PSMA1,PSMA2,HNRNPF,RUVBL1,CYP2C9,RUVBL2,TRIM11,PDCD4,UBE2H,PSMG3,CARS1,PSMB2,ADRM1,ROMO1,PSMA6,PSMC5,UBE2M,HEXIM1,ACACA,CFTR,PAAF1,KDM1A,HSPA5,DDX46,BAP1,RPL27,DERL1,CCDC92,RPL24,CDK12,MAP4,USP15,ZNF24,TPM3,FZR1,LMAN1,CDC5L,CD274,RAC2,TMEM31,PSMC3,TP53,RPSA,ACTR1A,DUSP1,PSMA5,NUP107,MEPCE,FKBP8,PSME1,ABCE1 |
| 1.818e-12 | -27.03 | MDM2 (MDM2 proto-oncogene) | protein interactions | 4193 | 609 | 250 | 19454 | 5460 |
SIRT7,PRKCB,MTDH,GTF2I,NUCKS1,RPL4,PIAS1,AATF,RPS14,BRINP1,TPT1,UBA52,CCND1,HSP90B1,SNAI2,RARS1,TRIM27,UBE2I,RPS20,ALB,UBE2L3,UBB,RPL22,PDCD5,RPL26,AR,KPNA6,USP14,STK11,RPL23A,IGF1R,HUWE1,RNF115,PAK1IP1,EGR1,RIGI,MDC1,EEF1A1,RPL15,UBE2B,CCDC3,SRP14,H2AZ1,EHBP1,RCHY1,RB1,TOP1,TSC22D3,PTP4A3,CDK9,MDM2,ZNF200,SUV39H1,EID1,NME2,ESYT1,RLIM,RNF10,TERT,PSMA3,NOP53,DUSP26,PSMC1,G3BP2,H2BW1,CDKN1A,DET1,AGGF1,PPARG,IER2,FKBP1A,TRMT6,S100A6,UBE2S,FOXP3,RPL37A,ACTB,TAB1,TUBB,TRIM46,GNB1,SCN3B,IRF1,SMARCE1,ZNF668,YWHAZ,RPS5,SP1,FHIT,HSP90AA1,SETD7,NEK9,ATF3,GADD45A,PPAN,PCNA,JAK1,UBE3A,RPS27A,UBE2A,VDR,RBM38,MAK16,JUN,SAP30,GTF2E2,EZH2,RPS11,RNF126,MAP1LC3A,TSG101,NDNF,CCAR2,EGLN3,DIRAS3,PDIA3,HNRNPA1,CDK5RAP3,UBE2D1,DROSHA,PSMD10,VCPIP1,HNRNPD,RPL23,PML,NBN,DLAT,RPS15,HDAC3,UBE2K,OGDHL,CLU,SUMO1,PAQR3,H2AB1,XBP1,H2BC11,DRD3,UBE2M,TFIP11,DYRK2,HEXIM1,ACACA,RPS3,PSMC5,CSNK2B,DAPK3,STAT5A,DAPK1,SMURF1,PPP1R10,NR1I2,SRC,DYRK1A,TRIM32,AKT1,ATF4,TRIM23,UBE2E3,DTL,CDKN2AIP,UBE2H,MYD88,CLPB,DHX9,HNRNPK,RRM1,TP53,TFRC,DDX42,TP53I3,SESN2,PSMC3,RNF8,IER3,UBE2N,UBE2G2,RPS27L,CMSS1,DPP4,KARS1,PGAM1,USP2,COPS5,CSNK2A1,PPM1D,GAPDH,RPS2,KPNA1,RPL10A,USP15,FOS,HSPA8,SF3B1,DDX5,EP300,YAF2,UBE2D3,PHB2,ADRB2,CTBP1,CSNK1A1,IRF2,VEGFA,SURF2,DLG4,ANAPC2,TCAP,PSMD4,FBXO22,IREB2,PSMB6,APEX1,RPL10,ESR2,CREBBP,MYC,SFN,PSMD1,RBBP8,FBXW11,COP1,PHF7,RPS26,S100B,RPL31,SDHC,RUVBL2,DNAJB4,CCAR1,MAGEC2,PAK6,RANBP1,CRTC2,RPS7,EEF2,RPL18,RPS23,FBXO31,EED,MAGED2,HSP90AB1,SIVA1,LAMP2,IFI16,UBE2E2,RPL6,XPO1,PPIB,CBL |
| 1.835e-12 | -27.02 | ALYREF (Aly/REF export factor) | protein interactions | 10189 | 377 | 169 | 19454 | 5460 |
AGR2,MRPL18,DDX23,MAGOH,MRPS26,WWP2,DIRAS2,MRPS35,PIK3R1,DDRGK1,MRPL9,HNRNPA1,XPO1,HNRNPL,PHB1,SRSF1,THOC2,FOLR1,EED,NGB,PDHA1,EZH2,SART3,RAF1,CSNK1E,NAA16,PAIP2B,SOX2,GNL1,TRIM37,CHCHD2,KRAS,TNF,SSRP1,POLDIP3,RAD21,PABPC1,SCYL2,SRSF7,EWSR1,MRPS25,BRCA1,MCAT,THOC6,ILK,RIT1,ICAM1,CUL3,CUL2,MTG2,AUH,MYC,SNRPB,RBM15B,RNF40,MATR3,RPL10,ESR2,SNRPB2,ERH,IREB2,CMTR1,TACO1,FAU,SNRPD2,SF3B4,PRMT5,EMC9,WDR77,STAU1,UFL1,SRSF2,MRPS7,SAP18,UPF3B,EXD2,PYM1,THOC3,DDX39B,SNRPA,EP300,HSPA8,SF3B1,SNRNP70,SMAD4,RBM17,GRSF1,COPS5,CD81,PRNP,TOP1,THOC1,MRPL50,RPS16,CAND1,SPPL3,FZR1,ZBTB2,MRPS23,RBM42,CDK9,RPL32,MGME1,ALYREF,MRPS9,CD274,DLGAP4,DISC1,RBM34,NUPR1,MRPL49,MRPL51,ILF2,INSIG2,TP53,MRPL11,MAP1LC3B,DDX39A,H2AX,VRK1,THRAP3,LSM4,OLA1,MEPCE,MRPS18C,RNF20,MRPL52,DHX9,HSD17B10,MRPS18B,ZC3H11A,RC3H2,LSM6,MRPS16,UBE2H,HERC4,CASC3,FGFR1OP2,AKT1,MAGOHB,VIRMA,DEK,ZNF330,EIF4A3,CCNF,PSPC1,PTEN,UBE2I,MRPS28,METTL14,CDK1,MRPS34,RPA2,LMNA,MTRES1,HEXIM1,RPL26L1,SF3A1,ATG16L1,CDK7,FBXW7,LSM8,PRPF4,SIRT7,RPA3,BAP1,RNF113A,PPIH,KIN |
| 1.883e-12 | -27.00 | EIF5 (eukaryotic translation initiation factor 5) | protein interactions | 1983 | 200 | 103 | 19454 | 5460 |
HDAC6,COPS5,CSNK2A1,CALR,RPL10A,RPS2,RPL32,DFFA,EEF1B2,G6PD,NCBP2,PRNP,EIF2B2,RPS27L,RPS16,RPSA,SRP72,GNAI3,RPL23A,ABCE1,CLPB,RIGI,EIF3E,HNRNPK,HUWE1,UBE2H,TXNIP,STK24,EIF3G,RPS20,CSNK2B,EIF2S2,CCNF,RPS3,PSPC1,RPL22,FERMT2,RPL13A,NDN,EIF4H,EIF3J,CD2AP,CDC42,ATG16L1,RPS14,UBE2M,EIF2B3,ZNF326,RPA2,LMNA,PML,RPA3,BAP1,EIF4E,RPL4,PDHB,RPS15,EIF3D,YWHAH,YWHAG,ATG7,XPO1,RPL6,HSPB1,UBFD1,RPLP1,RPLP2,EIF2S1,RPS7,RPL29,RPS23,EIF1AX,RPS11,BZW2,RPS24,PABPC1,RPL31,IMMP2L,RPS4X,NRGN,KRAS,RPL39,CDC123,RIT1,RPS26,YWHAZ,SNRPD1,PELO,EIF3K,RPL10,PRRC2A,APEX1,MAT2B,RPL35,TUBB,PAFAH1B1,RPL27A,NUFIP2,ISOC1,HSPA8,RPS28,STAU1,SRSF2 |
| 1.918e-12 | -26.98 | NRAS (NRAS proto-oncogene, GTPase) | protein interactions | 4893 | 683 | 275 | 19454 | 5460 |
ATP2B4,STX18,RAB27A,ABCE1,SLC16A1,RAB13,YIF1A,AKAP12,SRPRB,SLC6A8,PREB,CENPM,UBIAD1,SURF4,TFRC,PIK3CA,EXOC3,ACVR1,BMPR2,TMEM165,TAF2,ITGA6,ACSL4,COMT,SLC39A10,ADD1,MCL1,DNAJC1,ARL6IP5,PLSCR3,STX6,SLC38A2,RASGRP2,LMAN1,DHRS7,PLEKHO1,SELENOS,SLITRK5,SMAD4,TDRD7,SEPTIN6,ITM2B,LCP1,GAL3ST4,FTSJ1,FMO3,PIP4P1,SPTBN1,CD2AP,SNRNP27,CD46,RPA2,STX17,USE1,SSR1,VPS54,CSNK1G3,LEMD3,ATL1,NECTIN2,TRAF7,STX10,RALA,SC5D,ROCK1,IDE,SRC,RGL2,NDUFAF2,AKT1,SLC6A6,GORASP2,RAP2C,CISD1,ATP1A1,SNX5,TMEM87A,PIK3CG,CDK5,EFNB1,RABGGTB,KRAS,ROCK2,SLC35A2,VAMP8,SPG21,PLS3,PTRH2,SLC4A8,PTK7,TNIK,PCDH9,CORO1C,TCP1,VAMP7,RAB33A,PPFIBP1,TBC1D5,EXOC1,DDRGK1,CTNNB1,AGR2,CBL,ANKRD50,HSPA8,GOSR1,RER1,ABCC5,USP6NL,PTAR1,GOSR2,IL6ST,TMEM115,PRMT5,RCE1,LRIF1,ATP6AP2,MYRF,ESR2,MYC,PAPOLA,SLC1A3,SLC30A5,LAMTOR1,SLC38A1,NSDHL,RAB1A,DLG1,CCNY,SEPTIN7,SHISA2,SNAP23,WASL,TTC4,PSEN1,ARF4,CTNND1,ADD2,CCDC47,SLC29A1,PPIF,LBR,EEF1A1,SMAD1,ZDHHC8,PDLIM4,SRPRA,HRAS,PTPN1,EHBP1,DLGAP4,CDCA3,ARF6,EI24,RELL1,SLITRK2,HM13,DAG1,RAB23,POR,ESYT1,TIAM1,CD9,OSBPL8,RPA3,SLC2A3,PPIH,SPCS2,SLC7A1,NF2,YKT6,MPZ,TMEM209,CDC42EP4,RABL3,ARHGAP1,SEC22B,SLC35E1,CNP,ABHD5,FBP2,CTDSP1,SLC12A2,STOM,GOLGA5,SHOC2,AGAP1,HYCC1,PLP1,GAB1,VAMP3,ODR4,RPS20,MSN,F11R,YES1,FERMT2,SFRP4,VKORC1L1,DEPDC1B,HYCC2,HMOX2,RACGAP1,EPHA2,LRP6,PLSCR1,PLCB1,TRMO,SEMA4C,ETFA,AHCYL1,GOLGA7,FOXP4,FLOT1,HSDL2,RAF1,MARCKSL1,ARFGAP1,E2F4,CYB5R1,FAF2,IFNGR1,DCUN1D3,TULP3,VAMP2,VPS33A,STIM1,BZW2,STX12,PLD3,CYB5B,WDR6,PPP2CB,NEO1,TYMS,GJA1,AFAP1L2,INA,MPP1,SPTAN1,PPIA,WDR44,RAB11B,TMEM237,TAF7,ATG9A,C2CD2L,LRRC57,SLC20A1,CDC42EP2,TMEM185A,RP2,SRI,STX7,GJC1,FAM234A,WDR77,TOR1AIP2,NOTCH2,RGL1,EHD1,RAB6A,SLC23A2,FAM91A1,ARF1,SLC30A7,SPCS1,ABHD12,CHCHD3,NIBAN2,VEZT,PKP4,WDR20,SLC7A11,TNFAIP8 |
| 2.015e-12 | -26.93 | HNRNPH3 (heterogeneous nuclear ribonucleoprotein H3) | protein interactions | 3189 | 295 | 139 | 19454 | 5460 |
MIR16-1,CCNF,ENO1,NDN,AR,PPP1CC,MAT2A,ATP1A1,PIM2,UBE2H,SPOP,STK24,MIR145,MIRLET7I,HNRNPH2,MIR34C,SPCS2,MIR10B,RPA3,MIR205,NLE1,PML,HSPA5,MIR107,MIR29A,TTR,MIR7-3,MIR1-2,MIR34B,MIR21,HEXIM1,HNRNPH3,MIR7-1,RPRD1B,RPA2,MIR25,MIR106B,SSBP1,MIR429,ZBTB2,FZR1,DCUN1D1,CAND1,MIRLET7G,PRNP,COPS5,DPP4,GRSF1,MOV10,MIR34A,SNRNP70,ERG28,HSD17B10,MIR9-3,DHX9,MIR200A,SNIP1,MIRLET7C,RIGI,SMN1,MIR16-2,NEDD8,MIR15A,MIR200C,H2AX,MAP1LC3B,NUPR1,MIR20A,MIR17,MIRLET7B,ZMYM2,DLST,MIRLET7D,MAT2B,ESR2,MATR3,SNRNP40,MIR98,MCM3,MYC,CUL2,CUL3,CRMP1,MIR363,FBXW11,DCAF4,BRCA1,LMNB1,NMRAL1,HSPA8,PSMA3,DDX5,RAB5A,SNRPA,DNAJC3,HTR1A,MIR106A,HNRNPA0,UFL1,STAU1,EEF1G,PPP1CB,WDR77,HEXB,PPT1,EED,MIR141,MIR214,SRSF1,PHB1,MIR7-2,DYNC1I2,MIR9-1,XPO1,HNRNPA1,MIR29C,MIR143,WWP2,MIR1-1,MIR221,HNRNPD,MIR140,HSPB1,MIR31,EWSR1,MIR206,MIR9-2,HNRNPA2B1,RPS4X,HNRNPDL,SSRP1,HNRNPF,MIR155,MIR222,HEXA,PLD3,EZH2,PDHA1,CHMP4C |
| 2.094e-12 | -26.89 | LMAN1 (lectin, mannose binding 1) | protein interactions | 3998 | 428 | 187 | 19454 | 5460 |
DLAT,DERL1,RAB9A,TEX264,HSPA5,KDM1A,CDC42,LEMD3,CYC1,RPA2,SSR1,UQCRC2,CTSB,DNAJC5,GORASP2,ST13,RAB2A,RPL7A,ATP1A1,CALU,DNAJC10,BCAP29,SLC25A11,SLC6A8,FKBP8,RAB3B,UBIAD1,SNAP29,ATP5PB,PREB,MTCH2,TFRC,RAC2,CD274,COX4I1,CAMLG,TMPO,STX6,SLC38A2,TMED9,DNAJC1,DPP4,EDEM1,DHRS7,HSPA8,AKAP1,RAB5A,TMEM106B,EMC1,UFL1,PHB2,CNPY3,SEC62,EDEM3,BET1,PIH1D1,FAM83B,PHF21A,VDAC2,LMBR1L,CCDC90B,PPP5C,ATP6AP2,PSMD1,SLC38A1,FIS1,RPAP3,EFNB1,CYP2C9,TMEM87A,KRAS,NUDCD3,DNAJC25,ISG15,STBD1,TUBB4B,RAB4A,STX5,RAB35,RHOH,PPFIBP1,DDRGK1,LAMP2,RAB5C,DDX1,NDUFB8,FKBP4,RPA3,TMEM209,YKT6,UQCRC1,ST7,CDK7,RABL3,ARHGAP1,SEC22B,LMNA,GRM2,SLC12A2,VAMP3,STUB1,UQCRQ,VIRMA,SEC63,COPE,RHOJ,YES1,ATP5F1A,DEPDC1B,TUFM,HMOX2,EPHA2,SNAP23,EMC2,NSDHL,CTNND1,DNAJC30,TTC4,LBR,CCDC47,SERPINA1,HSPA13,HSD17B11,PTPN1,HACD3,SRPRA,CAV1,ARF6,HM13,LAMP3,ATP1B1,TMEM199,SLC25A46,ATP5MG,DNAJC7,OSBPL8,POR,ESYT1,TXNL1,PMAIP1,TTC1,DNAJC3,EXD2,PXMP2,STX7,NSFL1C,OTULINL,RND2,GINM1,PGRMC1,NOTCH2,TOR1AIP2,VAPB,ARMCX3,RMDN3,SEC61B,FAM91A1,VEZT,TMED4,RAB11A,HSP90AA1,LMNB1,RHOB,BAG2,TMT1A,RETREG1,FAF2,YIPF3,RAF1,MACO1,PLD3,CYB5B,STIM1,RPN1,CHMP4C,GJA1,WDR6,PHB1,IFIT2,CACYBP,DNAJB9,UBXN6,STOML2,CFC1,HAX1,RB1CC1,RHOG |
| 2.141e-12 | -26.87 | RPS18 (ribosomal protein S18) | protein interactions | 6222 | 372 | 167 | 19454 | 5460 |
BAP1,RPL27,RPA3,RNF113A,HMGB1,FBXW7,RPL4,RPS15,HSPA5,AATF,PIAS1,RPS14,CDK7,FGF13,CFTR,METTL14,RPA2,UBE2M,RPL26L1,RPLP0,HEXIM1,METAP2,PSPC1,RPS3,CCNF,RPS12,RPS20,GSK3A,RPL13A,NDN,RPL22,VIRMA,SMURF1,CCNB1,RPL7A,USP14,PPP1CC,RPL26,FBXO7,RC3H2,EIF3G,SPOP,UBE2H,MRPL52,RPL23A,HAPSTR1,RPL3,VRK1,HUWE1,EIF3E,RIGI,RPL17,MRPL22,RPS13,MEPCE,TP53,RPSA,INSIG2,FBP1,KBTBD4,UBL4A,RPL15,H2AX,DNAJC2,TFCP2,TNFAIP8L1,MRPL51,SRP72,RNF181,KRR1,RCHY1,RPL32,RPL12,MRPS9,PRR3,FZR1,CAND1,RPS16,RPL35A,MRPL24,TMPO,CDK9,RBM42,ENY2,COPS5,CD81,CSNK2A1,HDAC6,RPL24,SNRNP70,TUBG1,ATP6V1D,RPL10A,RPS2,RPS28,PYM1,STAU1,UFL1,G3BP2,PAFAH1B1,MTF1,RPL27A,H1-5,WDR77,EMC9,PIH1D1,EIF4B,FAU,RPS9,SEC61B,RPL37A,RPL35,TRIM29,LAMTOR3,APEX1,ESR2,RPL10,RPL19,CUL2,SFN,CUL3,MYC,ACO2,RPS29,RPL39,BTF3,BRCA1,RIT1,RPS5,ICAM1,RPS26,TRIP4,RPL31,RPS24,TRIM37,G3BP1,TNF,KRAS,RAD21,RPL28,RPS4X,B3GNT2,MSX2,RPS7,OTUD6B,CHMP4C,EZH2,RPL18,RPS23,RPS11,PHB1,RPL9,FOLR1,RPL8,RPLP2,RPLP1,RPL7,RPS10,RPL6,WWP2,EIF3D,DDRGK1,MAP3K14,XPO1,DRG1,RPL23,AHSA1 |
| 2.228e-12 | -26.83 | BIK (BCL2 interacting killer) | protein interactions | 638 | 131 | 75 | 19454 | 5460 |
PMAIP1,TMEM243,TMEM254,ORMDL1,SLC37A4,BCL2A1,BNIP3L,CTXN3,SEC22A,PLP2,TANK,BET1,PGRMC1,GOSR2,SLC35E3,RHBDL3,FAM3C,CMTM7,GRM2,VAPB,TMEM229B,SYNGR1,ELOVL4,VAMP3,BAD,PLP1,REEP4,HMOX2,CYB561D2,VAMP5,CREB3,REEP6,PLN,BAX,CYB561,TMEM147,SLC39A7,STX8,RUSF1,FKBP8,ADIPOQ,TMEM60,NRM,TMBIM1,SOCS3,YIPF4,UBIAD1,INSIG2,SELENOK,PGAP2,CYB5B,CRKL,TMEM14B,MCL1,AIG1,CNIH1,TSPO2,TMEM97,ANKRD46,ASB11,VTI1B,FATE1,TMEM107,CSNK2A1,MARCHF5,PMP22,BAK1,PLPP4,TMEM199,ADGRE2,FCGR1A,BCL2L1,BTN2A2,FAM241B,TMEM11 |
| 2.283e-12 | -26.81 | HNRNPK (heterogeneous nuclear ribonucleoprotein K) | protein interactions | 3190 | 675 | 272 | 19454 | 5460 |
CDC5L,MIR429,TMPO,RBM42,MIRLET7G,ARL6IP5,CAND1,FZR1,ARL4D,ITK,SYNCRIP,TSNAX,SNRNP70,API5,ELOC,CD81,COPS5,MIR16-2,CAPZA1,MEPCE,MIRLET7C,HNRNPK,NEDD8,DHX9,MIR9-3,RBM41,PSME1,TCEA2,MIR200A,RNF8,GRAP2,TFCP2,DUSP1,TP53,INSIG2,UBL4A,BCCIP,NMI,SRPK2,SRC,PPP1R10,SMURF1,ROCK1,KCTD9,UQCRC2,CREB1,UBE2H,GZMK,RBM7,PDCD4,IGF2BP1,SPOP,MORF4L1,MAT2A,MIR29A,HSPA5,MIR107,RASD1,SNX33,RNF113A,HNRNPH2,PML,BAP1,MIR10B,LEMD3,MIR7-1,HEXIM1,UBE2M,GSTP1,MIR21,WWP1,RPA2,CFTR,NEK2,GTF3C4,SUMO1,MIR34B,MIR9-1,SUMO2,HNRNPL,MIR214,EED,SRSF1,MAGOH,MIR140,YWHAB,DDX1,POU5F1,UBFD1,MIR221,AGR2,MIR31,CTNNB1,DDRGK1,YWHAH,MRPL9,MIR29C,XPO1,WWP2,MIR143,DCAF4L2,IFI16,DRP2,CCAR1,MIR155,TCF23,HNRNPF,KRAS,MIR206,EWSR1,RBM3,PABPC1,MIR9-2,KLHL23,HGS,ZRANB2,ZNF526,MSX2,RPS7,SOX2,MIR222,ISG15,SUPT5H,TRMT1L,APEX1,MATR3,ETNK2,MIRLET7B,CMTR1,H1-1,ICAM1,PSMD14,CKB,CCT2,CIRBP,BAG3,BTF3,MYC,STAU1,ADRB2,UFL1,HNRNPA0,EP300,YAF2,RAMAC,DDX5,SF3B1,DDX39B,SNRPA,PIH1D1,EIF4B,PPT1,MAP2K1,DUSP14,MDM2,CDK9,TOP1,KLF1,DCUN1D1,MIR25,PSMB1,PRR3,RCHY1,MIR106B,PTPN1,SMAD3,ZNF688,ZNF575,MIR34A,CRBN,HDAC6,RIGI,RNF20,CTNNBL1,HUWE1,FAF1,MIR17,MIR20A,DDX39A,EEF1A1,MAP2K3,MIR200C,MIR15A,FBP1,VIRMA,FERMT2,NDN,MSN,RPS20,UBE2I,GSK3A,ENO1,EIF4A3,CCNF,MIR16-1,CDC73,IVNS1ABP,MIR145,USP14,IFNAR1,FBXO7,CSK,PIAS1,FBXW7,HMGB1,MIR7-3,DESI1,GTF2I,MIR34C,MIRLET7I,MIR205,RPA3,DVL2,WTAP,METTL14,LSM2,LMNA,CDK7,MIR1-2,SF3A1,RBFOX2,DHX15,PPIA,SPTAN1,MIR141,PHB1,MIR7-2,FOLR1,HNRNPD,UCK1,AHSA1,MRPS26,MIR1-1,HNRNPA1,PIK3R1,PDIA3,SSRP1,SAR1B,PCGF3,G3BP1,HNRNPA2B1,SART3,CHMP4C,EZH2,LGR4,MAPK10,B3GNT2,MIRLET7D,ACTB,MRPL23,SNRPD1,RIT1,HSP90AA1,MIR363,RPS5,BRCA1,LMNB1,YWHAZ,MIR98,PRPF31,CUL3,CUL2,MIR106A,GPC1,PSMA3,ATP5IF1,CRY1,NMRAL1,EMC9,APOBEC3C,PPARG,CDKN1A |
| 2.372e-12 | -26.77 | RPS6KB2 (ribosomal protein S6 kinase B2) | protein interactions | 6199 | 258 | 125 | 19454 | 5460 |
BUD23,PPP2R1A,KIF2A,RPS7,TUBB4B,RPN1,RPL18,SNRPE,HSPD1,SLC25A5,CCT8,HNRNPA2B1,PABPC1,RUVBL2,PCNA,EWSR1,BAG2,RPS24,RTCB,RBBP7,G3BP1,RUVBL1,RPS4X,POLDIP3,PRDX1,PSMD3,RPL6,YWHAH,HNRNPA1,PPM1B,DDX1,LYZ,RPL8,RPL9,SRSF1,MAGED2,RPLP2,RPL7,TCP1,HSP90AB1,CCT7,SYK,TIMM13,XRCC5,HSPA8,EP300,DDX5,SRSF2,EEF1G,PSMC1,SNRPB,MCM3,CCT2,RPS26,HSP90AA1,RPS5,SERPINH1,TUBB,RPL19,RPL10,ESR2,STRBP,CCDC47,CCT5,YTHDF2,EEF1A1,TIMM8A,PSMC3,RPL3,RPL23A,HAPSTR1,DHX9,HNRNPK,FBXO25,RPS13,RPL17,FKBP8,PTGES3,MSH6,CAPZA1,MOV10,ANKMY2,TMA16,RPL24,DNAJC7,RPS2,RPL10A,TIMM8B,RPL12,AIFM1,RPL32,RPS14,CFTR,SSR1,RPLP0,ACACA,PPM1G,RPL27,BAP1,GTF2I,RPL4,HSPA5,HSPA14,AKT1,AKT3,RPL7A,SUB1,ATP5F1A,RPS17,RPL26,CFL1,TUFM,NONO,PDCD4,IGF2BP1,ATP1A1,PSPC1,STUB1,RPS3,TUBA1B,CSNK2B,EIF2S2,ALB,PRKCE,SRC |
| 2.423e-12 | -26.75 | TCTN3 (tectonic family member 3) | protein interactions | 26123 | 331 | 152 | 19454 | 5460 |
GPAA1,SEC11A,PDIA6,ERP29,SCD5,SLC39A7,EMC8,EMC10,HSDL2,NCSTN,RPN1,STIM1,CYB5B,TAPT1,RAB31,ASIC1,NDUFS8,PTDSS1,PDIA3,SLC38A9,PPIB,NDUFV2,EMC6,CSTA,DEGS1,JAGN1,DNAJC3,RER1,SSR3,SRSF2,UFL1,NDUFS2,TLCD1,EMC1,B9D2,SLC37A4,TOR1AIP2,BET1,PGRMC1,GOSR2,IDH3B,SIGMAR1,VAPB,NDUFA5,ELOVL1,CYB5R3,PIGK,LMBR1L,SEC61B,GPR89A,SLC30A7,SPCS1,REEP4,ATP6AP2,ABHD12,VEZT,TMEM38B,SLC1A3,SLC30A5,KCNJ8,SPCS3,VMP1,ZMPSTE24,CNIH4,NSDHL,RAB1A,EMC2,YIF1A,TMX3,ERO1A,SRPRB,TMEM33,FKBP8,LPCAT3,SLC6A8,PREB,CCDC47,LBR,ACADSB,NDUFS3,SFTPC,TFRC,SURF4,DHRS7B,SELENOF,CAMLG,SRPRA,HACD3,PTPN1,FA2H,SLC39A10,DERL2,DNAJC1,ARL6IP5,TMED9,TMPO,SLC38A2,LMAN1,ILVBL,SLC25A17,SELENOI,EMC4,DHRS7,ADIPOR2,TMEM199,CALR,MOV10,EI24,ORMDL3,HM13,ESYT1,POR,TMEM184C,OSBPL8,NUS1,FADS2,PML,DERL1,SPCS2,CERS2,YKT6,HSPA5,TMEM209,DAD1,SEC22B,RABL3,HACD2,CFTR,TRAM1,TMEM106A,SLC12A2,SSR1,HSP90B1,TRIM68,LEMD3,SCAMP2,GANAB,SLC11A2,TLCD2,COPE,SEC63,VKORC1L1,GSTK1,CSK,TMEM41A,RACGAP1,SLC35B4,HMOX2,DEPDC1B,DNAJC10,CALU,ATP1A1 |
| 2.472e-12 | -26.73 | XRCC6 (X-ray repair cross complementing 6) | protein interactions | 2547 | 810 | 317 | 19454 | 5460 |
PAEP,POLDIP3,KRAS,RUVBL1,HMGN4,VDAC1,EWSR1,RPL31,TOP2B,RINT1,CCT8,SDHC,ZRANB2,MTA2,BTG1,CRKL,MOB3C,STMN2,CAAP1,SOX2,ISG15,EEF2,MSX2,TOP3B,TRMT1L,MAX,DHX38,SUPT5H,LANCL1,MACROD1,EIF2S1,PGR,RPS10,SUMO2,TRIR,SNRPA1,CORO1C,EED,SWAP70,MGMT,CBL,ARHGAP5,AGR2,CTNNB1,DDRGK1,IFI16,BAZ1B,DDX50,UFL1,PHB2,HSPA8,SF3B1,HDAC5,EP300,YAF2,DDX5,DDX39B,SLU7,CD40,XRCC5,CSNK1A1,PIH1D1,ZNF362,CBX5,APEX1,PSMD4,MATR3,PSMD6,RRAS2,GTF2F2,IRF2,DLST,CMTR1,ICAM1,RBBP8,RBM27,RPS6KA4,BTF3,CREBBP,MYC,EPS8,PAPOLA,PHF1,MEPCE,H3C1,HNRNPK,DHX9,NAE1,SELENOF,FURIN,NUPR1,BIRC5,DDX42,CHAMP1,CBX3,TFCP2,IK,DISC1,ACADSB,H2AX,STRBP,SRFBP1,RPSA,TP53,RAP1A,ILVBL,MBD5,TMPO,SURF6,CAND1,FZR1,RAP1B,MCL1,SSBP1,ALYREF,CDK12,MAP4,SMAD4,SMCHD1,H2AC4,PPIL4,COPS5,CSNK2A1,PGAM1,RGS2,HSPA5,CLU,GAL3ST4,RNF113A,DLAT,ORC6,DDX46,BAP1,NBN,HEXIM1,UBE2M,TFIP11,RPA2,QRSL1,RNF146,GTF3C4,PPP1R10,SMURF1,NMI,DYRK1A,KCTD9,TAC1,PHAX,EIF2S2,MACROH2A1,PSPC1,ZNF330,PAFAH1B3,ZBTB33,LIG3,PTTG1,ATP1A1,ZBTB38,UBE2H,ALKBH5,MECP2,SNTA1,RC3H2,PRKACB,ST13,SLC25A1,SUGP1,SMARCA5,CCNB1,SUB1,PSMD12,SSRP1,DHX16,TRIM37,PCNA,UBE3A,BAG2,SRSF7,DNTT,NUDT5,TRIP4,RBPJ,SART3,JPT2,RNF126,EZH2,NGB,CHMP4C,PPID,JUN,NUP153,KIAA0408,GTF2E2,RAF1,FEN1,NAA15,ZNF263,LRWD1,RPLP1,THOC2,DNM2,PHB1,AHSA1,HNRNPD,RSBN1L,PDAP1,ATG7,HNRNPA1,HMGA1,PDIA3,PSMD3,PRPF19,COIL,UCHL3,CMTM6,NOP53,NSFL1C,NUP50,CFDP1,PSMA3,TERT,MFAP1,PPARG,MED23,EMC9,ADNP,CDKN1A,KCND3,RBBP4,UBE2S,PARP2,PAXX,BAX,RIT1,BRCA1,YWHAZ,SAMHD1,ACO2,HNF1B,NFYA,CUL3,CUL2,MDC1,MSH6,VRK1,THRAP3,SEPTIN7,HAPSTR1,ZC3H11A,HSD17B10,FAF1,ILF2,LBR,SERPINB9,FBP1,MDM2,CDK9,PLGRKT,TOP1,PRNP,TNKS,SMAD3,HACD3,H2AZ1,RCHY1,NHEJ1,EMX2,POR,EID1,HDAC6,GTF2E1,MOV10,EMC4,GTF2I,NF2,DGCR8,MTDH,PPM1G,SOD1,RPA3,HELLS,SIRT7,RARS1,LMNA,JUP,CDK1,TOX4,METTL14,CDK7,SF3A1,ATG16L1,SAP30BP,NFYB,TPT1,SNRPN,SCML2,VIRMA,NDN,TMOD3,GANAB,GTF2A1,TRIM24,PTEN,CCNF,OPTN,CTNNA1,ENO1,SMAD2,CDC73,HOXC4,TADA3,RUNX1,PPP1CC,USP14,AR,NONO,CNTNAP1 |
| 2.497e-12 | -26.72 | SLC25A3 (solute carrier family 25 member 3) | protein interactions | 5250 | 367 | 165 | 19454 | 5460 |
TECR,SH3BGRL,UQCRQ,SMURF1,VIRMA,SRC,PRKCE,RHOJ,GSK3A,PTEN,PTPMT1,SFXN2,CCNF,SMAD2,ATP1A1,UBE2H,RC3H2,ATP5F1A,FBXO7,TUFM,NDUFB10,AKT1,RALB,CSK,TOMM20,MRPL20,HSPA5,NF2,MRPL17,FBXW7,RNF113A,SQSTM1,RPA3,RPL27,IDH3A,DYRK2,MET,HEXIM1,UBE2M,CYC1,RPA2,GRM2,HSP90B1,METTL14,GABRA1,MRPL10,MX1,CDC42,CFTR,CDK7,ATG16L1,ILVBL,MYL12A,TMPO,CDK9,ZBTB2,CAND1,FZR1,ARF6,TOP1,MRPL50,SLC39A10,PTPN1,AIFM1,SDHB,HDAC6,COPS5,MOV10,PSMB10,HUWE1,GNG5,PC,RAB1A,SNIP1,MAP1B,SFXN1,SLC25A20,FURIN,RNF8,MAP2K3,TMEM205,UBL4A,TMEM126A,ATP5PB,TP53,MTCH2,MAD2L2,ESR2,RPL10,ACTB,MRPL13,SEC61B,BAD,CYB5R3,ICAM1,SCFD1,NTRK3,ATP1A3,RHOB,BTF3,TOMM40,ACO2,MYC,TMED4,CUL3,CUL2,G3BP2,UFL1,PPP2R2C,TMEM177,STAU1,YTHDF1,ADRB2,PHB2,HSPA8,HDAC5,NMRAL1,AKAP1,HADHA,ATP5MK,TMEM106B,PIH1D1,DHRS4,PRDX3,TOMM22,FBXO42,MTX2,ELK1,NDUFS8,EGLN3,EED,PHB1,OCIAD2,MRPS26,HSPB1,NDUFB8,AK2,MRPL9,NDUFV2,YWHAG,CTNNB1,MAP3K14,DDRGK1,WWP2,STOML2,G3BP1,KRAS,VDAC1,TRIM37,NDUFB5,NDUFA4,NDUFA12,EZH2,RPN1,AQP3,CHMP4C,PDHA1,ISG15,PPP2R1A,CYB5R1,TUBA1A,LGR4,RAF1,B3GNT2,E2F4 |
| 2.498e-12 | -26.72 | regulation of biological quality | biological process | GO:0065008 | 2936 | 1024 | 18204 | 5365 |
ARHGAP15,DRD3,SMAD4,DDI1,PDIA2,RNF128,SERPIND1,NOP53,BRS3,P2RY4,LMNA,CYFIP2,GPX1,RALA,CCL24,NPR2,MIR95,CTSK,HYAL2,CTNNB1,SLC1A1,CRTAP,BOK,HSD17B10,CAMK2G,NAA16,PDCD10,VDAC2,TTL,EP300,SNX5,MSN,CYP2C8,SLC8A1,CARTPT,MIR497,RIC3,TRIM24,ATP5IF1,GNAI2,MLLT11,MIR206,GRIA1,ADRB3,CDC42EP2,TUBA1A,RAB27A,SLC4A8,FGD2,DERL1,GRID1,BAD,CRY1,MIR545,GSK3A,L1CAM,TIRAP,LRP6,NCALD,TTI2,STAT1,JAK2,PTEN,STXBP1,DTD2,BCL2L1,ATP8A1,VEGFC,GPC4,GPR37L1,PPARA,UPRT,FLOT1,ADRB1,SULT1B1,NEUROD2,GRM1,GRIK1,MIR885,CPLX3,HSPD1,VPS33A,KCNA2,PRL,RNF122,UBB,CAMLG,CFL2,SLITRK5,SERPINA1,ABHD6,USP2,UBE3A,MIR185,DUOXA2,FGR,PCBP4,RNASEL,ASMT,YWHAG,KCNF1,THRAP3,MIR519D,HADH,VWF,MIR30B,MIR21,CD9,CACNG3,INHA,ANAPC2,AQP4,ENPEP,DHRS4,HACD3,UBE2B,MFN1,LST1,CREBL2,PROS1,GPRASP3,SYNCRIP,RTN4,EMP2,GNAZ,ILDR1,SMURF1,PCK2,DNM2,NOS1AP,KCNH1,ARPC3,DXO,IREB2,HYPK,CD36,MIR210,SNAPIN,PMAIP1,APTX,VSTM4,VAV2,AQP2,TSPAN18,SIN3A,PYURF,FCGR2B,RPS7,HSD17B6,NKX3-1,AKR1B1,UBL4A,SETD5,TMIGD1,CLU,KCNG3,CLTRN,TMEM108,RAP1A,EIF4A3,PLSCR4,SLITRK2,CCN3,HNRNPD,COL1A2,TAF9,ESAM,CRHBP,TUSC2,MIR24-1,SMAD3,KCNJ10,SLC7A11,CDH8,UMPS,LRRN1,C2CD2L,LRTM2,GRM2,DNLZ,HP1BP3,NDP,KCNJ3,NLGN2,FXR2,PLN,CD38,CD2AP,MIR181D,THBD,FGF13,GNA11,SRI,PABPC1,P3H1,IGSF11,NFKB1,TERT,KCNJ8,MIR491,MYL12A,SYBU,PML,CYP2C9,HCLS1,DISC1,TASL,LEP,SQSTM1,EPS8,TRIM21,ATF4,TM9SF4,TFPI,COTL1,PHB2,ANGPT1,C1QL3,DAG1,CALY,ADRA1A,SRC,NME1,SST,MTMR2,NRDE2,EXT1,PTGES3,PDSS2,KCNJ11,MIR135B,TACR3,PRKRA,RAB8B,IFNG,DYNLL1,MIR34B,ARHGAP5,MIR153-1,METTL14,CTNNBIP1,NTRK2,BORCS5,TOMM7,CCT5,FLRT2,C1GALT1C1,MKLN1,SLC30A5,MIR100,MIR625,UBASH3B,EXOSC3,BNIP3L,MIR29A,SEMA7A,BMPR2,SLC38A1,TMEM199,SLITRK1,MECP2,NDC80,MIR181C,GOLGA7,NFE2L2,FBXO7,AKR1C1,AKR1C2,NCDN,WASF3,ADTRP,CREBBP,WASL,GCLC,TRIM37,SELENOM,USP13,RAP2B,NCK1,TF,ATP5F1B,FGF10,METAP1,CHP1,ACTA2,RIMS4,SLC6A3,KRAS,PLSCR3,CD52,SLC35F6,ATP1A2,PICALM,CDK7,ATP1B1,CTNNA2,TNR,MIR20A,CCL21,PRCP,CIRBP,NFE2,TADA3,HNRNPC,CRHR1,SUMO1,PRKCB,CHGA,MCHR1,FOSL2,ZC3H14,MIR708,TMOD2,NLRP6,ATP2B4,CCT2,PFDN2,MIR200C,CHRM1,NCKAP1,HPS6,SNAP25,FGF12,DAD1,CDK5R1,SYNDIG1,HSP90AA1,MOV10,ATP6AP2,APLN,INPP5K,HTR2A,MIR190B,KCNJ2,CYP26A1,HSPB1,PRDX3,MIR142,CDC20,ZSWIM7,IER3,TMSB10,CREB1,ATP1B3,WWP2,HCRT,GLRA1,RIMS3,ATP6V0B,ZNF207,MIR106B,PSEN1,ARL6IP5,EGR2,GJC1,ATG9A,AP2A1,PTN,INSYN2A,MIR324,IDE,ATP1A3,ALKBH5,SMAD2,MIR342,MIR421,ZMPSTE24,CYP2D6,GFI1,GABRB2,MIR208A,ZCCHC17,CAV3,MEF2C,HSP90AB1,RAB1A,PIM2,BLOC1S3,FKBP1B,USP8,RC3H2,HTR1A,ARPC2,ATP6V1A,PFDN6,CAV1,RHOB,AGER,LRRC24,MIR23A,PYCARD,HRAS,CXCR4,TRIM46,LARP4B,CXCR1,STX1A,CDC42SE2,RGS2,MPIG6B,NTNG2,RDH11,KLK6,MME,ABHD17A,MIR495,YTHDF1,GABRB3,HMGB1,TMEM106B,RAB11A,PPP1R1B,CNTNAP1,VAMP7,MSX1,MIR145,CX3CR1,TRAF2,DBH,IL10,ROCK2,PTGFR,CACNB3,RAF1,ADIPOQ,NAA15,CCR3,DDRGK1,HSD17B1,PLSCR1,MIRLET7C,GAS2,CCR2,F2,SLC29A1,DDR1,SCN2B,CFTR,NEFL,PRKCA,LMAN1,CTTN,ADNP,COCH,MIR424,LGI1,QRSL1,FBXW11,ASIC2,BORCS8,SH3GLB1,JPH4,GLRA2,NETO2,ATAD1,CFDP1,KCNA3,VAMP2,DHRS3,SLC4A10,LRRC8A,DNAAF10,DNAJC2,PTPN11,NETO1,C1QL1,CCL11,ADORA1,PRDX2,COMT,FGFR1,P2RY1,MIR340,SCN1B,TENT5D,TMEM30A,SPPL3,CLIC4,ARF1,LPAR1,TMEM183A,BLOC1S2,CHST10,HSD17B11,RPL23,PTGER4,KCNK10,PPARG,CLSTN3,LIPA,RHOJ,JUP,MIR106A,ADH1A,STX12,MIR193A,PDE9A,DCP2,F11R,TMOD1,RAP2A,TSPO,CHRNA7,CHRNB2,AK3,NCSTN,RPS5,PYCR1,CAPG,FZD6,YTHDF2,MKKS,CNOT7,EGR1,PNPLA4,GAPDH,TPBG,EPO,SLC6A4,CLN8,MIR211,ITGA2,SLC25A31,PFKFB2,CCT7,PDRG1,EXOSC8,AGR2,RTF2,IL1B,KCND2,AKT1,NPY,FAM107A,PPP3CA,WNT7A,ELAVL4,OXTR,RETN,MT3,NPVF,MAP1B,VDR,BAK1,AGTRAP,GNG3,CALR,NSG1,ABCB1,MYL12B,CNOT2,ENY2,UCP2,DIO3,IGF1,DKC1,CNR1,SOD1,AR,RND2,LHFPL4,MIR130A,MIRLET7B,IL2,PAIP2,CCND1,KIT,FLRT3,PID1,MIR320A,UTS2,CPE,KCNK17,XBP1,CD59,INSYN2B,CYB5R4,DIO2,RGMA,CPLX2,TMEM88,PRKCE,SCPEP1,SYVN1,NRP1,CCL28,GNB3,KCNH8,MIR125A,NR1H2,B4GALT1,KCNS1,KCNK13,DAPK3,CDC42SE1,TENT4A,CARHSP1,E2F4,OXSR1,HAX1,MIR130B,SNTA1,PRNP,BVES,AKT3,CA2,PLXNC1,GNAO1,ACAA2,PAIP1,PTP4A3,GNAQ,IL6,LAMP2,GP9,POPDC2,ENPP4,BAX,TRAF3IP2,TREML1,MOSMO,LRRTM1,ACSL4,ACVR1C,BORCS6,MIR223,DTD1,MIR96,SRD5A3,CDC73,AQP11,SYT4,GRIA2,KCNMB2,ADM2,HDAC3,MLLT6,PLCB1,TNFRSF1B,POPDC3,INSYN1,CIB2,UTS2R,CHMP2B,CDC42EP4,TAPBP,LPAR2,UCN,WNT10B,EDNRA,SIPA1L1,MIR423,PLEKHO1,MIR204,CCAR2,SELENOT,TESC,NOG,DPM2,HDAC6,FBXW7,TMBIM6,CD40,BOLL,ARFGEF1,SAV1,SCG5,CCR4,SYK,NPY1R,YES1,LACRT,CNOT6L,VMP1,TMOD3,ASIC1,TNRC6C,MIR101-1,SCN3B,LHB,NAIF1,SPTBN1,PPIF,CDC42EP3,STAT5A,VIP,NPTX1,CYP21A2,CYRIB,VAMP3,PICK1,YIPF5,DPP4,GLRB,SLC12A2,CYP1B1,MYLIP,TLR2,MIR373,RAB5A,CCNH,CTNND1,DMPK,SNAP23,HSD17B3,OPRL1,CHRM3,MIR16-1,SLC16A10,RDH10,CACNB4,DRD1,PIH1D1,PDE2A,TUBB,EHD3,DHRS11,CCL2,SYP,CLCN6,NPPC,NHERF1,IGF2BP1,UGT2A3,FASLG,HSD17B8,CD40LG,VAC14,MIR140,PIK3CG,UTP25,ADH1B,RETSAT,UQCC2,RB1CC1,NEGR1,PHAX,CTTNBP2,GPIHBP1,STAU1,ROCK1,P2RY12,RGS7BP,APEX1,NLGN1,RAB22A,SPTAN1,PIK3CA,TIAM1,F7,PAFAH1B1,RPAP3,CACNB2,FBXL3,CAMK1,CRYM,SERPINC1,NIBAN2,FZD4,TCP1,OPRK1,AMIGO1,PRKACB,CCL1,YWHAZ,OSM,CPLX1,KCND3,CUL3,KLF1,PIK3R2,PIK3R1,NR2E1,PRRT1,CAPZA2,PPM1K,NF2,BORCS7,VEGFA,CTSA,PRELID1,MTPN,AP2S1,FGF23,MIR137,ADRB2,MCM8,CFAP20,CCR7,CCR6,SEMA5A,RABL3,NAPG,SPP1,VAMP8,KXD1,DHX9,DKK1,COL3A1,RAB3B,CXCR6,MIR30D,CMTM6,SLC7A8,JAGN1,MIR9-1,KCNMB1,GABRG2,AANAT,ADD1,PPFIA2,OSBP,MIR192,HRH2,DHRS7,CHST9,FRRS1L,ALB,DLG3,CNOT6,DLG1,RAB3A,IFRD1,GLRX,CYP1A1,HBB,FIS1,CBLN1,TNNI3K,ABITRAM,S1PR4,BAG3,CCR5,GHRL,HNRNPA0,CSNK2A1,SLC66A2,CCR1,GNA14,KCNIP2,SYNGR1,SLMAP,KDM1A,CTSB,MIR29C,EIF4EBP2,OR51E2,CFL1,STK3,RNASEK,C1QL2,HEY2,ATP6V1D,TLCD1,SOD3,PCSK2,REN,CCL3,HNF1B,YWHAH,RASL10B,CRYAB,AGO1,SOCS2,LRRTM3,CDC42,PPIA,SFRP1,IGF1R,PTGER2,FERMT2,EPHA4,AKAP12,KCNB1,CCL5,FCHSD2,ZDHHC15,KCNC1,ADD2,MIR146A,CD81,CCDC186,MIR149,CBLN2,AQP3,NPTN,TACR1,MYD88,CDC37L1,OPHN1,EFNA5,AP2M1,RUVBL2,CDKN2AIP,DKK3,SEPTIN7,GPR35,CMA1,SWAP70,FURIN,SSH3,F9,TYROBP,FASTKD5,IL1RAP,CHRDL1,CCT8,PLG,RNF5,MIR98,TBC1D24,EMILIN1,KCNMA1,CDK5,RHOU,CXCL12,RAB11B,HFE,CYP3A5,CYP4F12,DDAH1,STUB1,RANGRF,CSRP1,PHB1,RUVBL1,PDIA3,PDE12,LRRTM2,RDH12,ATP1A1,MIR191,AVPR1B,SLC25A4,DIO1,NDUFAF2,PPT1,MUL1,CAPZA1,CX3CL1,TBCCD1,ATP6V0E1,CYP17A1,TNF,CYP11B2,ACTB,GGCX,SLC25A27,H1-5,FOXC2,ALDH1A3,CLDN3,ARF6,MIR214,MIR17,GJA1,CXCR3,SLC25A5,CYP11B1,LRRC4B,GPR89A,PTGER1,ILK,SDR16C5,TMSB4X,LRAT,CSTPP1,TENT5C,PALM2AKAP2,APLNR,IFI6,DLG4,ARF4,TMEM165,HOMER1,TMEM14A,ZBED3,ST3GAL4,PPIB,HSPA8,CYRIA,LARGE1,GHR,BAG2,CRABP2,UGT1A1,MIR26B,ITGAV,GABBR1,ACKR3,ANO3,CNOT8,CNP,GABRA1,SOD2,MIR1-1,HPCA,TP53,STK4,TAC1,MDM2,PPFIA3,F10,PAPSS2,DSTN,MIR212,CXCL13,SLC16A1,CAMKV,RHOG,CDO1,TLCD2,HEXB,LRFN3,CYP2C18,GPHN,MIR195,TRIM44,GPM6A,CYP27B1,S100B,C1QTNF1,GABRA2,RNF139 |
| 2.584e-12 | -26.68 | PSMC4 (proteasome 26S subunit, ATPase 4) | protein interactions | 5704 | 323 | 149 | 19454 | 5460 |
ALDH1L1,MYC,CUL3,CDKN3,PSMA4,JPT1,PSMD1,RFC5,LAMTOR1,FTSJ3,BRCA1,PSMD14,FBXW11,RIT1,LMBR1L,DLST,ANAPC2,PSMD4,TENT5C,RBBP4,FBXO22,PSMD6,PSMB6,RORB,APEX1,PSMB3,PAFAH1B1,PPP1CB,PSMB7,HERC3,TXNL1,HSPA8,TRIM5,HDAC5,CRY1,AKAP1,PSMA3,UFL1,DDI1,PSMC1,IFI16,PSMD3,PFDN5,DDRGK1,ELP6,PSMD10,AGR2,UBFD1,AHSA1,PSME2,PSMB4,PHB1,PSMB5,FBXO32,KRT8,SUMO2,EGLN3,RAF1,B3GNT2,ARFGEF1,PPP2R1A,ISG15,GFPT1,RPS7,RPN1,POLR2C,MOB3C,TMT1A,UBE3A,BAG2,COX8A,PSMA2,KRAS,PSMA1,PSMD12,PSMB2,USP14,AR,RC3H2,ATP1A1,UBE2H,PSMG3,CCNF,PSMA6,TUBA1B,PSMC5,TMOD3,ADRM1,UBB,SMURF1,VIRMA,PSMC4,GABRA1,NEK2,CFTR,PAAF1,UBLCP1,RPA2,SSR1,GRM2,HEXIM1,UBE2M,ACACA,RPA3,PPM1G,PRIM2,BAP1,DDX46,EXOSC4,NR1I3,SQSTM1,DESI1,ATG4C,MOV10,KXD1,ZNF24,ZFAND2B,CCDC92,PSMD7,CD274,CCDC3,PSMB1,FZR1,SPPL3,PRNP,CDC5L,TP53,ACTR1A,PSMB9,GPAM,TMEM31,MAGEA4,NUPR1,PSMC3,RAD23B,ZFAND2A,MAP1B,PSME1,HSD17B10,SEM1,HUWE1,PSMA5,TGFBR2,TOLLIP,DNAJC30,MEPCE,VTA1,FKBP8,RIGI |
| 2.651e-12 | -26.66 | Cap-dependent Translation Initiation | REACTOME pathways | R-HSA-72737 | 125 | 77 | 10285 | 3229 |
RPS10,RPL39,RPS7,RPS27L,RPL26,RPL10A,RPL29,RPS15,RPL23,RPS9,UBA52,RPL7,RPL37A,RPS23,RPS11,RPL4,RPS12,RPL27,RPS2,RPL9,RPL31,RPL18,EIF3D,EIF3J,RPL12,EIF2B5,EIF4E,RPL19,RPL35,RPL10,PABPC1,RPL26L1,RPS3,EIF3G,EIF2B3,RPL17,EIF3E,EIF2S2,RPL22,EIF1AX,EIF2B2,RPS28,RPS17,RPS26,RPL15,RPS5,RPL8,RPLP2,RPS27A,RPL27A,EIF4H,RPL10L,RPS13,RPLP0,RPL13A,EIF2S1,RPS29,RPLP1,RPS4X,FAU,RPL32,EIF5B,RPL3,RPS16,RPS24,EIF4A2,RPS20,RPSA,RPL6,RPS14,RPL7A,RPL28,EIF3K,RPL23A,RPL24,EIF4B,RPL35A |
| 2.651e-12 | -26.66 | Eukaryotic Translation Initiation | REACTOME pathways | R-HSA-72613 | 125 | 77 | 10285 | 3229 |
RPS20,RPSA,RPL6,RPL3,FAU,EIF5B,RPL32,RPS24,EIF4A2,RPS16,RPL24,RPL35A,EIF4B,RPS14,RPL23A,RPL7A,RPL28,EIF3K,RPL8,RPS5,RPLP2,RPS17,EIF1AX,RPS28,EIF2B2,RPS26,RPL15,RPL13A,EIF2S1,RPS29,RPLP0,RPLP1,RPS4X,RPL27A,EIF4H,RPS27A,RPS13,RPL10L,RPL12,EIF3J,EIF2B5,EIF3D,RPL31,RPL9,RPL18,RPL17,EIF2B3,RPS3,EIF3G,EIF2S2,RPL22,EIF3E,EIF4E,RPL19,RPL26L1,RPL10,RPL35,PABPC1,RPL29,RPL10A,RPS15,RPL23,RPL39,RPS10,RPS27L,RPS7,RPL26,RPS11,RPS23,RPS12,RPS2,RPL27,RPL4,UBA52,RPL7,RPS9,RPL37A |
| 2.675e-12 | -26.65 | HSPD1 (heat shock protein family D (Hsp60) member 1) | protein interactions | 3329 | 941 | 360 | 19454 | 5460 |
EEF2,ETFB,TRMT1L,CFAP68,NDUFA12,PDHA1,TUBB4B,TRIM21,KGD4,CTNNB1,DDRGK1,NDUFV2,YWHAG,DCAF4L2,IFI16,FAHD1,YBEY,RBM5,HDHD5,HSP90AB1,SUMO2,SNRPD3,SNRPA1,RAB1B,HNRNPL,EDEM3,MRPL12,MTMR6,CSNK1A1,CNDP2,EIF4B,ACAA2,PPT1,THBS3,SF3B1,DDX39B,PACSIN3,ADRB2,NDUFS2,UFL1,TMEM177,SNRPB,BTF3,HNRNPAB,MYC,COP1,MRPS25,PSMD14,MCPH1,MRPL13,TRMT11,DKK3,SMU1,MTG1,DLST,DLG4,ESR2,GTPBP8,INSIG2,ATP5PB,CBX3,MAP1B,PSMB10,MEPCE,PDE12,NEDD8,MRPS33,GAPDH,LYPLAL1,TRMT5,AKAP8L,TMEM70,TDRD7,MGME1,SSBP1,MRPS9,TLR1,CAND1,PLG,TFB1M,FGFR1,DLAT,GFM1,PML,BAP1,DDX46,CLU,OGDHL,NME4,CEP70,ETFBKMT,SPMIP8,SLC25A1,NDUFAF2,UBE2H,CDKN2AIP,OAT,BICD2,GLOD4,MRPS16,SF3B6,UQCRC2,SLC25A39,CDC20,PPP2R1A,RAF1,HSDL2,B3GNT2,SNRPE,NME1,NDUFS6,PCDH17,MRPS11,HINT2,HNRNPA2B1,BCKDK,THNSL1,HSPD1,PREPL,SAR1B,IMMP2L,HNRNPA1,PDIA3,MRPS26,ATP6V1A,DHX15,EGLN3,CDKN1A,MAPKAPK5,PSMA3,EXD2,ATPAF2,CMAS,HSCB,PPP2R2C,MRPL16,PIK3R3,PMPCA,PYCR1,ACO2,MTG2,AUH,NLRP3,BAX,DCAF4,BRCA1,LRRC28,SNRPD2,SNRPD1,BAD,MAD2L2,NDUFAF4,B4GALT3,AURKAIP1,MAP2K3,NDUFA2,FBP1,NDUFS3,SFXN1,FAF1,RAB1A,ABHD10,MRPS18C,FASTKD5,VRK1,TRIM63,HUWE1,PCED1A,GRSF1,MOV10,MRPS23,MRPL24,CDK9,TMCC2,MRPL50,CDK7,PCK2,SF3A1,RARS1,METTL14,GID8,RPA3,DVL2,MRPL20,FBXW7,DNAJC8,IFNAR1,FBXO7,CDC73,CCNF,MRPL53,VIRMA,NDN,SOX2,ISG15,SMNDC1,NUDT19,PABPC1,CCT8,CMTR2,VDAC1,KRAS,MRPL9,HSPB1,AGR2,DCAF5,EED,SRSF1,HMG20A,RHOH,NDUFAF3,PAFAH1B1,SETD9,PIH1D1,ADSS2,YAF2,HSPA8,HDAC5,MRPS7,STAU1,OXCT1,SF3B4,CCDC90B,TACO1,ATP5F1B,USP16,HADH,GLRX5,MTCH2,MRPL47,UBL4A,ACADSB,NHERF1,TFCP2,THG1L,MRPS18B,ATP5PF,DUSP19,RASL10B,REXO2,ABHD16B,CSNK2A1,COPS5,RBM17,FAM20C,NOS1AP,TUBG1,CD4,PREP,COX4I1,SYNCRIP,EEF1B2,SDHB,CDC5L,TMPO,CFTR,GABRA1,MRPL10,HECTD1,ACACA,HEXIM1,UBE2M,SPRYD4,RPA2,QRSL1,RNF113A,HSPA5,EIF4E,MRPL41,GSTK1,PTPN11,ATP1A1,SPOP,MRPS28,CYP21A2,SMURF1,MYG1,KCTD9,MRPS21,LGR4,TXNRD1,SF3B5,OXNAD1,EZH2,MRPS17,ETFA,TRIM37,G3BP1,NKIRAS1,MRPS35,CLPX,BCL2L1,AHSA1,SLC25A28,RHOG,GATD3,PHB1,FOLR1,NDUFS8,CCAR2,IDH3B,PRDX3,NDUFA5,ATP5PO,HADHA,NMRAL1,FTL,FBXL4,PDE4B,AK3,CUL3,MRM2,CUL2,RIT1,FAM107A,FHIT,TAFAZZIN,SNRPB2,GNB1,MTM1,BCS1L,EEF1A1,PPIF,TBK1,HSD17B10,CLEC7A,SLC25A10,HSPE1,MPG,HDAC6,BAK1,GMPPB,DNAJC7,RCHY1,EEF1AKMT3,ATP5PD,PRNP,CCND1,SAP30BP,ATG16L1,GRM2,MRPS34,LMNA,FLCN,AMACR,POLDIP2,USP14,TUFM,AR,ATP5F1A,PYCR2,PNPLA4,CA2,PIP4K2C,PTEN,ACAT1,OPTN,INPP5K,STUB1,TXN |
| 2.717e-12 | -26.63 | RPL3 (ribosomal protein L3) | protein interactions | 6122 | 667 | 269 | 19454 | 5460 |
H1-6,KRAS,NUP42,RPL28,RPS4X,RPL31,PABPC1,GLE1,PDHA1,SMNDC1,SLC1A2,DCUN1D5,RPL18,RPS23,TRMT1L,MAGEB10,ISG15,DNAJC25,SOX2,RPS7,RPS10,ISG20L2,LYAR,SUMO2,HSP90AB1,RAB35,SRSF1,RBM5,EED,AGR2,PEX3,MAGOH,DRG1,DDX50,IFI16,RIOX2,RPL6,WWP2,DDRGK1,NGDN,CTNNB1,UFL1,STAU1,MRPS7,HDAC5,HSPA8,SF3B1,RAB5A,MRPS18A,PIH1D1,CSNK1A1,RPL27A,MTF1,FBXO42,PAFAH1B1,MATR3,SNRNP40,ZCCHC7,APEX1,RPL10,SURF2,CMTR1,ZNF189,SMU1,MRPL13,FTSJ3,COP1,RPS26,NSA2,H1-1,APOBEC3B,MYC,CREBBP,BTF3,H3C1,MEPCE,RPL17,METTL18,MRPL52,SNIP1,RPL3,DNAJC2,RBM34,TBC1D4,KBTBD4,UBL4A,TP53,RPSA,SPPL3,RPS16,DNAJC1,CAND1,RBM42,TMPO,DKC1,CDC5L,SURF6,MRPS9,RPL32,ARL4D,TUBG1,RPL24,SNRNP70,RPS2,IGFBP4,RPL10A,ENY2,PLEKHO1,COPS5,E4F1,API5,RPS15,WDR55,HSPA5,RPL27,SNAPC1,BAP1,NLE1,PML,RNF113A,RPA2,WWP1,UBE2M,TFB1M,HEXIM1,ZNF770,FGF13,CFTR,RPL10L,RSL24D1,SRPK2,PSPC1,RPS3,SEC61A1,FGFBP1,MACROH2A1,MECP2,TRIM23,RC3H2,CDKN2AIP,UBE2H,RPF2,RPL7A,ZSCAN25,TNF,G3BP1,RBBP7,TRIM37,MRPS17,SAR1B,TRIP4,PPAN,HECTD3,RPS24,EZH2,CHMP4C,RPS11,SART3,B3GNT2,MAK16,RPL7,FOLR1,RPL9,RPL8,PHB1,RPLP2,HP1BP3,RPLP1,WDR12,MRPL18,TRAF6,MRPS26,RB1CC1,DICER1,RPL23,MRPS35,MAP3K14,YTHDF1,NOP53,COIL,G3BP2,EMC9,H1-5,RPF1,RPL7L1,RPL35,RPL19,ZNF22,ARF1,PELO,RPL37A,SEC61B,RPS9,RHOB,DCAF4,BRCA1,RPS5,HSP90AA1,RIT1,NOP16,CUL2,CUL3,MRPL16,ZNF668,HUWE1,PAK1IP1,VRK1,RPS13,MRPS18C,NKRF,RPL23A,LLPH,SRP72,MRPL51,FBP1,MAP2K3,TAF1D,AURKAIP1,EEF1A1,EXOSC8,RPL15,RPL35A,SRP14,SMAD3,RPL12,KRR1,RCHY1,ARL10,MPHOSPH10,GRSF1,SPATS2L,HDAC6,NPM3,DGCR8,NF2,RPL4,HMGB1,FBXW7,PIAS1,BRIX1,UTP23,AATF,RPA3,SIRT7,KIN,MTDH,METTL14,ZNF574,RPLP0,RPL26L1,MACROH2A2,RPS14,RBFOX2,ATG16L1,COPE,NDN,RPL13A,RPL22,PELP1,CCNF,EIF4A3,METAP2,PRKRA,RPS12,RPS20,RPL26,AR,TUFM,PPP1CC |
| 2.902e-12 | -26.57 | membrane organization | biological process | GO:0061024 | 761 | 312 | 18204 | 5365 |
VPS39,SLC25A31,VPS4B,SNX33,TIMM10,FOLR2,AKT1,VAMP8,NAPG,LMNA,GCLC,TOMM22,WASL,EMC4,EMC2,BAK1,SEC22B,HYAL2,CHP1,ABCB1,SNX18,SYNGR2,BOK,VAMP1,PACSIN3,OSBP,REEP3,CIBAR1,ROMO1,PLSCR3,CAVIN2,UQCC3,VDAC2,KLHL12,SOD1,BANF1,EMC1,LHFPL4,PICALM,SLC35F6,RAB3A,REEP4,DLG1,CHCHD3,TRAPPC3,BECN1,CRISP1,ATP5IF1,TOR1AIP2,NAPA,ATP1B1,TIMM8A,IZUMO1R,ARHGAP25,UGCG,BAD,FCGR1A,SLC66A2,VIPAS39,SYNGR1,PRKCB,GSK3A,KCNIP2,HGS,STX7,CAV2,PLA2G5,BCL2L1,TFG,ATP8A1,RER1,STXBP1,MIR29C,PTEN,TSG101,LYZL6,SNAP91,EMC10,FLOT1,MTCH2,SERPINA5,SNAP25,TLCD1,LMNB1,SNAP29,STX8,HSP90AA1,ROPN1B,CDK1,AKT2,TRAPPC13,SCLT1,VPS33A,CHCHD6,CDC42,ACAA2,CAMLG,CHMP1A,DEGS1,GOSR1,GCA,TOMM40,GOSR2,RTP4,BAX,IER3,LRRC4,GLTP,KCNB1,FCHSD2,CD9,LPCAT3,ATP2C1,ATG9A,TRAPPC1,UBE2I,OCRL,SYT4,SNX3,TRAM2,EXOC1,DNM2,EMP2,RTN4,ZMPSTE24,HDAC3,SMURF1,VTI1B,AP2M1,CAV3,SNAPIN,VPS18,PMAIP1,CHMP2B,RAB1A,CD36,TRAPPC6B,SAR1B,TIMM29,TMEM95,CHMP2A,CAV1,TMEM11,CPTP,STXBP6,TMED9,STX11,ALKBH4,STX16,CHRDL1,ARHGAP12,PREB,CXCR4,S100A10,FCGR2B,PITPNA,FCHO2,EMC6,UBL4A,VPS28,ELMO1,NSFL1C,STX1A,GOLPH3L,CORO1C,CLU,SEC22A,PITPNB,NPC2,ATL1,VAMP7,YKT6,CLTRN,FA2H,TIMM13,STAR,SEC13,SLC25A4,RILPL2,VMP1,PLSCR4,MUL1,PPT1,NAIF1,CD2,SPTBN1,UBAP1,VAPB,PLAAT3,DES,PLSCR1,ESYT1,PPIF,YIPF5,C2CD2L,EXOC5,DPP4,AKAP8L,PICK1,VAMP3,AIF1,EXOC8,TRMT10B,EXOC3,AZIN2,VPS16,TRAPPC10,NLGN2,USE1,GLRB,PRKCA,SEC61A1,CD2AP,DMPK,SNAP23,WDR83OS,MIR17,STX6,SH3GLB2,IZUMO1,UBXN2B,TIMM8B,SLC25A5,TAFAZZIN,TRAPPC6A,SH3GLB1,EXOC2,CIDEB,TRAM1L1,PLEKHA8,FOLR1,VAMP2,TOMM20,NHERF1,SYP,TRAPPC2L,NECTIN2,GHITM,STX18,PMP2,FASLG,DLG4,PARP11,TMEM14A,TOMM70,HUWE1,TMEM147,TOR1B,CHMP1B,LARGE1,SLC25A46,HSPA8,ANO3,TMEM33,TRAM1,VPS4A,TOM1,CNP,GNPAT,STX10,TMCC1,SURF4,BCS1L,STARD5,VCPIP1,ARF1,NLGN1,TP53,TMEM30A,PAFAH1B1,STX5,ARFGAP3,SEC23A,BLOC1S2,LYZL4,SGTA,BET1,BET1L,YIPF4,AP3S2,STARD4,CHMP4C,STX17,TOMM7,STX12,APOO,TNFAIP8L3,CHMP5,CCDC47,MTX2,TSPO,AGK,CUL3,RABIF,TLCD2,MIR29A,PPM1K,BNIP3L,OSBPL8,TRAPPC4,GPHN,VRK1,TOMM6,PRELID1,MYRF,EMC8,EMC9,MAIP1,CLN8,TMEM170A,CNTN2,SAMM50 |
| 3.093e-12 | -26.50 | HDAC5 (histone deacetylase 5) | protein interactions | 10014 | 365 | 164 | 19454 | 5460 |
YWHAG,HNRNPA1,XPO1,YWHAH,HR,PSMD3,PRPF19,DYRK1B,YWHAB,HNRNPD,DDX1,PSMB5,PPP2CB,SRSF1,MYEF2,PHB1,RPL9,SIN3A,CCT7,DHX15,ANKRA2,HSP90AB1,PPIA,RPL7,CCAR2,TCP1,HNRNPL,ACTN4,TUBA1A,PPP2R1A,NEU1,RPS11,MTA2,NME1,TUBB4B,RPN1,EZH2,VPS33A,PDIA6,BAG2,PCNA,RUVBL2,ATF3,HNRNPA2B1,PABPC1,CCT8,MEF2C,HSPD1,MCM6,RPS4X,VDAC1,ETFA,RUVBL1,ZBTB16,HNRNPF,RBBP7,BRMS1,MCM3,MCM4,PSMD1,IKZF2,SFN,MYC,LMO2,HSP90AA1,YWHAZ,CKB,CCT2,PHF21A,PRMT5,RAN,NFKBIA,VDAC2,GNB1,CBX5,PSMD6,TUBB,RBBP4,ATP5F1B,RFXANK,PRDX3,PRKAB1,SLC25A3,CTBP1,DDIT3,HADHA,HDAC5,SF3B1,XRCC5,PRKD3,DDX39B,TNFSF10,PHB2,EEF1G,SUV39H1,CSNK2A1,NFKB1,RPL10A,TFE3,SMAD3,CDC5L,TOP1,KCTD3,CAND1,SOX9,EGR2,CCT5,TP53,RPSA,ILF2,TAB2,TFRC,CAMK1,HSD17B10,DHX9,RPL3,SFXN1,SLC25A11,MAP1B,LTBR,PRDX4,CSE1L,PSMA5,H3C1,NONO,TUFM,ATP5F1A,RPL7A,SLC25A1,ATP1A1,OAT,XPOT,IGF2BP1,NR2E1,ACAT1,UBE2I,PSMC5,GANAB,EIF4A3,RPS3,UQCRC2,TFEB,UBB,LDHA,PSMC4,SF3A1,KLF4,HAUS2,RARS1,RPLP0,HSP90B1,CDK1,H2BC12,PRDX6,PGK1,HNRNPH2,HSPA5,BCL6,GABARAP,MARS1,MEF2A,RPL4,KDM1A,HDAC3 |
| 3.122e-12 | -26.49 | response to organonitrogen compound | biological process | GO:0010243 | 915 | 365 | 18204 | 5365 |
TIMP1,SRSF4,MECP2,ALPL,PDE1B,TICAM1,NFE2L2,SHOC2,EIF2B5,FBXO44,OPRK1,MAN1A2,AMIGO1,PIK3R1,CCDC47,PIK3R2,TACR3,CAMP,MIR143,P2RY12,PDCD4,ROCK1,GPIHBP1,ICAM1,RNF121,F7,TIAM1,PIK3CA,REG1B,PIK3CG,MIR140,LEP,INSIG2,BACE1,CALY,SRC,DAG1,GNG2,KCNJ11,MGARP,EXT1,CSH1,GNA11,EIF2S1,DRD1,KCNJ8,NFKB1,PDE2A,NHERF1,NPPC,FOS,STAT5A,GRM2,P2RY11,TLR2,RARRES2,CYP1B1,THBD,CD2AP,BIRC2,TAF9,CRHBP,HNRNPD,RAP1A,ASIC1,SMAD3,STC1,SLC2A1,STK11,HDAC6,FCGR2B,DERL2,CD40,TMBIM6,SYK,GNB1,NLRP1,CIB2,LDOC1,GUCD1,CD36,EDNRA,TXNIP,WNT10B,ADSS2,SIN3A,PAX6,TNIK,PSMB2,JKAMP,DNAJB2,CD9,HADH,HM13,SELENON,MGST2,JAK1,PLCB1,PCK2,TLR9,GNRHR2,GNAQ,MIR107,MMP9,BGLAP,GNAO1,UQCRC1,MIR379,CSK,AHCYL1,IL6,FCER1G,ERLIN2,UBE3A,DNTT,SLC2A8,ACVR1C,YWHAG,UPRT,PPARA,SLC1A3,PRNP,FOXP3,LDLR,CA2,ERRFI1,AKT2,DERL1,TUBA1A,ATF1,SYVN1,RAMP3,GSK3A,CRY1,PRKCE,STAT1,LRP6,PCSK9,BCL2L1,PPP5C,JAK2,TRIM24,SLC8A1,CNR1,NCOA5,IL2,SEC61B,XBP1,GRIA1,GPT,GPX1,RETN,OXTR,SLC1A1,CTNNB1,GH1,TNFAIP3,CTSK,SLC1A2,MAP1B,NPR2,AGTRAP,PIK3R3,CALR,NSG1,EP300,RNF103,NFKBIA,IGF1,UCP2,SELENOS,GRB10,ITGA2,UBXN6,DRD3,TLR6,AKT1,TBC1D4,AIFM1,IL1B,ELAVL4,P2RY4,KBTBD2,UBE2G2,PPP3CA,SLC6A1,EIF2B2,CHRNB2,EZH2,CHRNA7,FAF1,EDEM3,NCSTN,MYRF,EGR1,TRIM44,RNF139,NR4A2,SLC6A4,CCNA2,RPL23,SGTA,SP1,UFL1,LIPA,PPARG,SESN2,JUP,CHMP5,KLHL22,TSPO,UFD1,BTG2,GAB1,NQO1,CDO1,CDKN1B,HPCA,GPR173,GNAI3,HADHA,TP53,TNFSF10,MDM2,TLR4,TOMM70,HOMER1,ZBED3,KLF4,GHR,ADORA1,PTPN1,TSHR,P2RY1,COMT,TMEM38B,CYP11B1,SLC22A12,MRGPRX1,TYMS,OGG1,RB1,CITED1,PTGER1,CASP4,RAB31,HSP90B1,CYC1,CDKN1A,VAMP2,FOLR1,INPPL1,EDEM2,FOXC2,CASTOR2,CFTR,NEFL,GJA1,PPP1R1B,ERLEC1,MIR145,DBH,RAF1,TMUB1,IL10,ROCK2,ACTB,CYP11B2,SHMT1,ADIPOQ,TNF,HRAS,AGER,MIR98,RNF5,FBP1,CXCR4,CXCL12,RGS2,CDK5,GABRB3,TOP2B,STUB1,DNAJC10,MEF2C,CAV3,STAMBPL1,ERLIN1,HTR1A,CAV1,CD81,PSEN1,MIR146A,EGR2,ATP1A3,IDE,MYD88,BRCA1,GABRB2,HSPA5,SOCS5,FAF2,SOCS2,SFRP1,CREB1,IGF1R,DEFB124,MIR200A,EPHA4,SOS2,MIR106B,KCNC1,KCNB1,OPRM1,HSP90AA1,INPP5K,REN,HTR2A,CDK1,REG1A,CRHR1,TWIST2,RAP1B,FOSL2,GNA14,SHC1,HDAC5,CAV2,GAD2,OS9,DHX15,KDM1A,MIR200C,EIF4EBP2,EDEM1,TLR7,RAB13,DNAJB9,UBXN10,CTNNA1,SOX9,STAT2,CPEB1,MIR20A,EIF2B3,GJB2,SESN3,PCNA,AANAT,GABRG2,IL1A,TMUB2,SLC6A3,SULT1A3,ADTRP,ADRB2,FOLR2,FAM8A1,CDH13,STAT6,SDF2L1,GSTM2,GCLC,COL3A1,PTPN22 |
| 3.181e-12 | -26.47 | regulation of multicellular organismal process | biological process | GO:0051239 | 3113 | 1079 | 18204 | 5365 |
XRCC5,RNF26,CYRIB,TBK1,ZBTB39,ACOT13,STAT5A,DPP4,PTHLH,NTN4,EEIG1,VAMP3,RNF10,MIR373,MYLIP,TLR2,G6PD,ZNF287,CYP1B1,SLC12A2,DMPK,SGMS2,OPRL1,CHRM3,MIR16-1,JMJD8,EHD3,HPGDS,NHERF1,IGF2BP1,IL2RA,NPSR1,MAP2K6,NPPC,CCL2,CLEC9A,DUSP6,STK11,NME2,FBXW7,HDAC6,SGF29,TESC,MIR208B,NOG,EAF2,ACVR1B,SAV1,RAB14,CD40,NPY1R,FGF16,PITHD1,SYK,HILPDA,PROM1,NLRP1,ASB1,PRKAB1,FA2H,YES1,GPR171,GPAM,TRIM32,GLUL,PDCD1,CERS2,SCN3B,MIR101-1,PARP2,ATRAID,SPTBN1,CD2,VSIR,TNFRSF9,OPRK1,CAPN2,FZD4,STIM1,NIBAN2,SERPINC1,BSCL2,KCND3,CCL1,OSM,MIR30E,AMIGO1,PIK3R1,NR2E1,SETD4,CUL3,NF2,TIMP1,MIR874,IL23A,VEGFA,FGF23,PRELID1,SIT1,MTPN,ALPL,FABP5,PPM1B,HSPB6,TLR1,IL15,MIR137,MIR939,THY1,PIK3CG,PDE4B,NECTIN2,MIR140,FASLG,CD40LG,RNF41,UTP25,CD58,TMEM176B,IL18,CAMP,MIR15A,MIR143,PDCD4,ROCK1,GPIHBP1,FIG4,TNNT2,NLGN1,TCIM,CACNB2,PAFAH1B1,ELOVL3,F7,PIK3CA,CD47,TIAM1,IL17F,RND2,AR,KLRD1,SOD1,CNR1,MIR492,CCND1,TGFBR2,MIRLET7B,IL2,TRIM63,MIR130A,FLRT3,KIT,XBP1,MET,MIR320A,MIR448,RGMA,DIO2,MIR10B,PRKCE,ACP5,FGF1,MIR125A,NR1H2,PLA2G5,GNB3,NRP1,PCSK9,ITGA2,TLR6,KCND2,AKT1,BMP1,TGFB3,IL1B,MIR182,PPP3CA,WNT7A,NPVF,MT3,MIR877,RETN,TOX,OXTR,RBBP4,GH1,TNFAIP3,GSTP1,VDR,MAP1B,MIR675,ASPA,SKIC8,CALR,GRPR,NFKBIA,IGF1,SAP30,SPRED1,DIO3,BRD9,PPP1R11,UCP2,CNOT2,CDC73,IFNA2,MIR96,LPCAT3,FABP4,MMP20,SYT4,SFN,SELENON,KCNMB2,ZBTB16,MIR148A,MIR383,SMARCD3,TNFRSF1B,PLCB1,TLR9,HDAC3,ADM2,NUS1,UCN,CD80,ANXA4,CLEC6A,MIR204,ZBTB33,EDNRA,FOXS1,NMI,WNT10B,MAD2L2,RIGI,PAX6,SMARCE1,EMC10,GPR137,TMBIM1,DAPK3,KLHL25,SNTA1,PRNP,BVES,SPRY1,HAX1,IQSEC1,CD274,FOXP3,AKT3,FUT1,MIR1224,DHPS,ERRFI1,ACTL6A,PPP1R12A,HS3ST5,PLXNC1,ASPM,GNAQ,CD86,PYDC2,MMP9,GADD45G,GNAO1,ADIPOR2,MIR379,ZBTB2,GP9,POPDC2,ENPP4,ID4,AGPAT1,IL6,HAPLN2,ELF1,FCER1G,DDX1,SLC7A1,MMP14,MACIR,ACVR1C,MIR223,TMEM100,LRRTM1,NKX3-2,GPM6B,CSNK2B,PDCD1LG2,ARF6,IRF4,FOXC2,AIF1,NLRP3,CEBPG,GJA1,MIR17,MIR214,TBC1D10C,ZNF365,LRRC4B,NLRP2,RB1,TNNC2,MIR338,MIR105-1,TMSB4X,CDKN1A,PLG,LURAP1,MZB1,IL1RAP,DUSP10,MIR98,TBC1D24,EMILIN1,ITGB8,HFE,PLAC8,CXCL12,BCL6,CDK5,FGF7,ORMDL3,RANGRF,DDAH1,LRRTM2,RUVBL1,ING1,PHB1,AVPR1B,TESPA1,FCGR2A,ATP1A1,MIR1298,CX3CL1,BRMS1L,RBPJ,MUL1,XCL1,ACTB,FGF3,TWSG1,TNF,UFL1,CXCL13,TNNI1,MIR212,MIR503,TNFAIP8L2,HOMER3,PI16,KLHL22,CCDC134,CDKN1B,LHX2,GTF2I,DROSHA,MIR195,B2M,CCSAP,CYP27B1,TRIM15,APOC2,LGALS3,C1QTNF1,KPNA2,HMCES,LUM,DLG4,APLNR,TLR4,ZBED3,ST3GAL4,KLF4,MIR147A,IP6K1,GHR,PPIB,MIR99B,MGP,MIR26B,TMEM38B,CRABP2,LEPR,TNFAIP6,MIR1-1,SYNJ2BP,MAP3K3,SOST,STK4,MAEL,TP53,FKBPL,ACTL6B,BRINP1,SDCBP,MIR188,SDC4,MDM2,BANF1,IFRD1,DLG1,MIR215,SNAI2,BECN1,TNNI3K,CBLN1,EFNB1,DICER1,NDFIP1,SOX9,RHEB,IL1R2,PAEP,DHRS7B,PROK1,RGN,GHRL,TMEM176A,MIR488,TOB2,SAP30L,IRF8,KCNIP2,HGS,PPP1CC,CCR1,HDAC5,MAP2K1,ING5,KDM1A,CD200R1,IL5,OR51E2,MIR29C,TLR7,BHLHE40,HAND2,CFAP20,ADRB2,UAP1,SEMA5A,CCR7,STAT6,ISG15,DHX9,DKK1,VAMP8,MIR25,FAM20C,SPP1,RFLNA,OTUD7B,LTB,ADD1,DUSP3,MAP2K3,MIR192,HRH2,PLD3,CD209,NLRP9,CD81,MIR146A,CBLN2,MIR149,AQP3,FXN,CD46,MYD88,TACR1,TAF5L,NPTN,IL4,MIR504,HTRA2,IL20RB,SOCS5,LDLRAD4,MIR150,SEPTIN7,GPR35,RUVBL2,EFNA5,ING2,CMA1,MAVS,ZBTB17,FURIN,CHID1,CPTP,CLIC2,TYROBP,OPRM1,CFL1,STK3,IL6ST,CSF2,BTN2A2,IRF3,HEY2,IL12A,REN,BCL10,MIR132,LILRB1,ID1,YWHAH,FRZB,HNF1B,CCL3,MIF,ATP5F1A,SOCS2,LRRTM3,AGO1,NUPR1,FBXO32,FERMT2,SFRP1,MIR302B,FLCN,IGF1R,AKAP12,DEFB124,TLR3,MIR200A,EPHA4,CST3,ZNF322,EFNA3,CCL5,MIR378A,TRIB1,CTLA4,NINJ1,LRTM2,LRRN1,TLR5,CCL19,SFTPD,TRAF6,NLGN2,GADD45A,FXR2,KCNJ3,AGGF1,ZBTB25,MIR222,TICAM2,THBD,MIR181D,CD38,CD2AP,PLN,IGSF11,SRI,FGF13,ARG2,IL15RA,KCNJ8,TERT,NFKB1,SOSTDC1,PML,SLC25A44,BMPR1B,DISC1,CHI3L1,HCLS1,FOS,GFUS,ADIPOR1,STAP1,NFKBIL1,NKX3-1,FCGR2B,MACROH2A2,MINAR1,KLF10,CLU,MIR205,TMIGD3,TRIM62,SELENOK,TFRC,TUSC2,CRHBP,KLRC2,RHBDD3,CCN3,WNT2,EIF4A3,MIR920,SLITRK2,SERPINB1,KMT5B,TMEM108,SMAD3,MIR24-1,DUSP22,STC1,CTNNBIP1,MIR153-1,TLR8,FLRT2,MIR296,IFI16,PGK1,NTRK2,IRF1,BRMS1,PQBP1,GSTO1,AFAP1L2,GTF2IRD1,MIR100,MIR29A,MOG,UBASH3B,EXOSC3,BMPR2,SEMA7A,TFE3,MIR181C,BMPR1A,MECP2,SMARCB1,SLITRK1,PRMT6,NFE2L2,TICAM1,FBXO7,ATF4,KRIT1,CD200,NOVA1,TRIM21,HNRNPK,LEP,PHB2,TFPI,FGL2,ADRA1A,SRC,MIR34C,DAG1,ANGPT1,TNFSF12,MTMR2,SRGN,TACR3,MIR135B,LGR4,HOXB8,RAB8B,MEF2A,PLCL1,IFNG,ARHGAP5,MIR34B,MIR873,MIR497,SLC8A1,CARTPT,ARRDC3,SS18,GAMT,CTDSP1,MIR155,MIR221,MIR206,CD14,EIF2AK2,RLN2,GNAI2,MIR377,ADRB3,TNFSF13,LMO4,BAD,DEFB114,G0S2,CD34,KPNA6,L1CAM,LACC1,GSK3A,CRY1,STAT1,BST2,MIR573,TIRAP,JAK2,PTEN,ASB3,SELENOS,INO80E,TANK,GRB10,SMAD4,AMELX,SDHAF2,DRD3,RNF128,PRMT5,MIR136,STARD13,LMNA,TMEM106A,CCL24,SLC1A1,CTNNB1,CTSK,HYAL2,SHLD1,WDR77,CAMK2G,KARS1,EP300,DR1,PDCD10,INHA,MIR30B,MIR21,FGFBP1,CD9,MTG2,HADH,MIR519D,LILRA2,MIR375,ANAPC2,MSX2,GPRASP3,ELAPOR2,PROS1,TIA1,LST1,GLIPR2,JAK1,RGCC,NOS1AP,SMURF1,MIR548C,RTN4,EMP2,MIR33B,MIR197,POLR3F,BAP1,MIR210,CD36,MIR129-1,SIN3A,TSPAN18,IFNGR1,FLOT1,PPARA,PELI1,GPR37L1,VEGFC,GRM1,MIR10A,ADRB1,HSPD1,LDLR,ENO1,MIR885,TRPC1,KCNA2,PRL,OTX2,JUNB,PNP,MIR107,BGLAP,BTG1,DLGAP4,KBTBD13,CSK,RSAD2,ABHD6,SLITRK5,FGR,POLR3B,MIR185,IL12B,FOXP1,STOML2,BCL7C,PLSCR1,MIR657,DES,RHOH,F2,CCR2,MIRLET7C,XAF1,LDB1,ACVR1,CFTR,NEFL,PRKCA,SCN2B,ANKH,CGAS,MIR424,CTTN,ADNP,ASIC2,RAG1,ZBTB45,ELOVL6,JPH4,SPHK2,CXCL10,VAMP2,TNFRSF14,ICOS,PYCARD,MIR23A,HRAS,MIR361,ZNF304,AGER,LRRC24,TAPT1,CD226,RHOB,BATF,GABPA,TRIM46,S100A10,CXCR4,EPHA2,INO80C,RGS2,STX1A,MAPRE2,BCL7B,HMGB1,CD1D,CORO1C,MIR495,MME,PRKX,VAMP7,TRIM6,RAB11A,LY96,RPS3,NKX6-2,NMBR,MIR145,CX3CR1,CCM2,TRAF2,DBH,MSX1,SLC39A10,FERD3L,IL10,ROCK2,MIR640,CCR3,RBBP7,MIR505,LBH,ADIPOQ,PTGER4,FUNDC2,MIR30A,SFRP4,RACGAP1,SP1,PPARG,CLSTN3,MIR106A,PRKCQ,JUP,GPNMB,AAMP,FAXDC2,RHOJ,BTG2,ZBTB6,UFD1,TSPO,GAB1,F11R,MIR193A,PDE9A,IL7,ITK,CHRNB2,EZH2,CHRNA7,YTHDF2,MIRLET7G,MYRF,IKBKB,IL34,TGFB1I1,EGR1,GAPDH,MKKS,RAD21,MIR28,NR4A2,TPBG,EPO,SLC6A4,PTGDS,TFPT,CDK6,DDIT3,TRIM27,DHRS3,TOMM70,CCL11,NETO1,MIR590,PTPN11,ADORA3,ADORA1,SGIP1,SCAMP5,TSHR,VASH1,NKAP,FGFR1,P2RY1,HELT,PRDX2,RAC2,MIR34A,IL13,MITF,SCN1B,CYGB,IL21,CLEC7A,SVBP,IDO1,CTSC,MIR133B,CXCL8,MAFG,LITAF,ATP1A2,ATP1B1,TNR,FZD3,CTNNA1,PRCP,TADA3,MIR20A,CCL21,SUMO1,CRHR1,SETD3,TRAF3IP3,OAS1,FOSL2,LTA,CHGA,PRKCB,MIR708,MACROH2A1,ZBTB26,SMAD1,ATP2B4,MIR200C,NLRP6,IRF7,TNFSF18,PROX1,ADTRP,MTDH,WASF3,GREM1,MIR152,TPPP,KLK3,GSTM2,C1QC,GCLC,PTPN22,SPRED2,TF,CPT2,ADAMTS1,NCK1,IL2RG,FGF10,ATP5F1B,CRYBA1,IL1A,TGFB2,MIR144,MBD5,KRAS,NOTCH2,SLC6A3,ACTA2,PTN,PLPP6,HBEGF,CD4,LILRB4,GJC1,PSEN1,EGR2,ATP1A3,MIR324,SMAD2,MIR342,TCTA,MIR31,BRCA1,MIR208A,IFIH1,RUNX1,ZMPSTE24,MEF2C,CAV3,MSTN,BLOC1S3,FKBP1B,VGLL4,PTPRZ1,RAB1A,CD28,CBFB,HTR1A,RC3H2,MEAF6,MTG1,ACHE,IFNB1,TRIM11,CAV1,PRDX4,TNFSF8,FGF12,TGIF2,HSP90AA1,SYNDIG1,INPP5K,HTR2A,DDT,MIR194-1,RPS6KA4,OSR2,CDK1,ATP6AP2,APLN,SASH3,KCNJ2,CD83,SLC20A2,MIR142,HSPB1,PTGES,MYC,CREB1,FRMD8,MIR126,SOS2,GLRA1,HCRT,DLX1,MIR106B,G3BP1,GPSM3 |
| 3.198e-12 | -26.47 | positive regulation of response to stimulus | biological process | GO:0048584 | 2266 | 810 | 18204 | 5365 |
DRD3,INO80E,GRB10,SMAD4,PRMT5,MIR136,MIOS,FAM53B,UBE2V2,UBE2V1,CYFIP2,RALA,GPX1,CCL24,KLK5,TMEM106A,SHLD1,HYAL2,CTSK,CTNNB1,BOK,KARS1,PDCD10,SNX5,EP300,CRKL,UBE2N,CARTPT,DIRAS2,MIR221,ARRDC3,GNAI2,CD14,EIF2AK2,MIR206,TNFSF13,ADRB3,SMCHD1,G0S2,DEFB114,BAD,GSK3A,RAMP3,DVL2,LACC1,TIRAP,BST2,TTI2,IRAK1BP1,STX7,P2RY10,JAK2,PTEN,LIMS2,MORF4L1,TRAF7,VEGFC,GPR37L1,PELI1,FLOT1,MIR449A,NEUROD2,ADRB1,MIR10A,GRM1,VDAC1,DMAP1,LDLR,HSPD1,MIR186,CD79B,PRL,TRIM34,UBB,RSAD2,CSK,SPG21,ERP29,IL12B,UBE3A,POLR3B,FGR,STOML2,PEA15,FOXP1,MIR519D,VWF,MIR21,FGFBP1,MIR30B,MSX2,LILRA2,CPNE1,RGCC,UBE2B,GLIPR2,ELAPOR2,EMP2,RTN4,CD36,MIR210,POLR3F,PMAIP1,VAV2,RRAGB,TTC23,SIN3A,STAP1,ADIPOR1,RPS7,FCGR2B,NKX3-1,ATF3,OTULIN,RALB,CLU,TFRC,TRIM62,TMEM108,KMT5B,PIK3AP1,RAP1A,CCN3,KLRC2,TAF9,DUSP22,CD63,MIR24-1,SMAD3,ALKAL1,NINJ1,CTLA4,TLR5,CCL19,GRM2,TLR10,MIR222,NDP,TICAM2,NLGN2,GADD45A,TRAF6,GSKIP,LAMTOR1,CD2AP,CD38,MIR181D,THBD,ALOX5AP,IGSF11,NFKB1,TERT,KCNJ8,CRADD,FAM168A,PML,HCLS1,DISC1,CHI3L1,PSPC1,BMPR1B,TASL,LEP,CD1A,TRIM21,HEXIM1,PHB2,ANGPT1,MIR34C,ADRA1A,SRC,TNFSF12,LGR4,PRKRA,PDCL,DOK5,TAB2,IFNG,SERINC3,RNF146,GPR37,MIR34B,BIRC5,NBN,EIF2B5,ACTR2,SHOC2,NTRK2,LMO3,NTRK3,IFI16,MIR296,TLR8,AFAP1L2,PQBP1,TRIM3,EXOSC3,MOG,MIR29A,SEMA7A,BMPR2,ADGRG1,NDC80,SMARCB1,BMPR1A,NFE2L2,TICAM1,AKR1C2,GREM1,MTDH,ENHO,PROX1,CREBBP,KLK3,CDH13,C1QC,PTPN22,SOX2,PDE8A,USP13,NCK1,SPRED2,PCNA,FGF10,GKAP1,MIR144,TGFB2,IL1A,CLPB,FCN2,ACTA2,KRAS,NOTCH2,MBD5,ADAMTS20,PICALM,LITAF,IFI35,CTNNA1,CCL21,MIR20A,TRIM22,RNF126,OAS1,RAP1B,TRAF3IP3,PRKCB,SHC1,CHGA,FOSL2,LTA,PAGR1,TMOD2,RIT2,CAV2,MIR1260B,ACTN4,IRF7,NLRP6,MAD2L1,USP15,HSP90AA1,ATP6AP2,HTR2A,DDT,SASH3,HSPB1,MIR142,GPR17,MIR126,MYC,DOK6,SOS2,GPSM3,ARL6IP5,PSEN1,TNKS2,CD4,HBEGF,TRIM26,PTN,FAM83B,CLDN1,BRCA1,SMAD2,GFI1,MIR208A,IFIH1,MSTN,MEF2C,HSP90AB1,CD28,PIM2,FKBP1B,USP8,MEAF6,RC3H2,TNKS,TAB1,GPBAR1,CAV1,IFNB1,SLC20A1,CD226,PLEKHF1,AGER,MIR23A,PYCARD,HRAS,CXCR4,TMEM198,STX1A,PTK7,INO80C,KLK6,FEM1A,CXXC5,MBL2,CD1D,HMGB1,BCL7B,MAPRE2,RPS3,LY96,TRIM6,VAMP7,MSX1,MIR145,TRAF2,CX3CR1,IL10,ROCK2,CACNB3,SLC39A10,RAF1,ADIPOQ,CRLF3,FGF17,MAP3K11,TMEM126A,PLSCR1,BCL7C,F2,CCR2,CD1C,ACVR1,DDR1,PRKCA,ADNP,CGAS,H2AX,FBXW11,ZNF622,SPHK2,RELL1,CXCL10,EYA3,DDIT3,NONO,TFPT,PTPN11,NETO1,MICB,TOMM70,FGF22,ADORA1,RAC2,PRDX2,PLPP4,P2RY1,FGFR1,CLEC7A,IL21,VPS72,FKBP8,CTSC,SPPL3,IDO1,CD1E,CXCL8,LPAR1,RRAGA,SFRP4,RPL23,SRARP,CSNK1A1,PTGER4,CCDC22,LIPA,ZNHIT1,GPNMB,RELL2,JUP,SLA2,PRKCQ,SESN2,STK24,F11R,OSBPL8,CHRNA7,EZH2,ITK,IL7,RPS20,GAPDH,TGFB1I1,IKBKB,IL34,TPBG,EPO,ITGA2,RPL26,TMED4,TLR6,AGR2,NCR3,IL1B,TGFB3,AKT1,PPP3CA,WNT7A,NPY,MIR182,MT3,TXN,BAK1,VDR,GID8,TNFAIP3,GH1,GRPR,CALR,MIR675,SPRED1,CIBAR1,IGF1,NFKBIA,LPAR6,LAT2,CNR1,SOD1,KLRD1,AR,PAK2,IL2,MIRLET7B,TGFBR2,KIT,FAS,MET,TSPAN5,XBP1,MIR10B,PRKCE,GLCE,CDK5RAP3,NRP1,PLA2G5,FGF1,PPP5C,PPP3R2,TFG,OR2AT4,DAPK3,GPR137,SMARCE1,HAX1,OXSR1,MIR1224,MATR3,AKT3,FOXP3,CD274,ACTL6A,GADD45G,MMP9,CD86,PTP4A3,ASPM,IL6,NDST1,AGPAT1,ENPP4,TRAF3IP2,BAX,FCER1G,DDX1,UBE2K,DNAJC27,TMEM100,FABP4,MIR96,TNIK,CDC73,SEMA4C,SELENON,LCP2,NACC2,MCL1,SH2D1A,OCIAD2,MGST2,HDAC3,TLR9,IFNK,PLCB1,SMARCD3,CASP12,CD80,BABAM1,OPTN,LPAR2,UCN,WNT10B,DSTYK,EDNRA,NMI,CLEC6A,RIGI,GPR65,MAD2L2,TRIM5,CCAR2,STK11,CREB3,PRR5L,S100A8,ZDHHC17,HDAC6,FBXW7,RGL2,ARFGEF1,CD40,ACVR1B,NLRP1,CCR4,FGF16,SYK,YES1,BIRC2,LACRT,TRIM32,CYRIB,TBK1,XRCC5,DIRAS1,TMEM97,CYP1B1,CD1B,RARRES2,TLR2,MIR183,CACNB4,MIR16-1,PIH1D1,DRD1,PDE2A,WBP2,JMJD8,NUP62,MAP2K6,NPPC,NPSR1,NHERF1,FASLG,MIR140,PDE4B,NECTIN2,PIK3CG,THY1,SCHIP1,WRAP53,RB1CC1,IL18,CSH1,LAMTOR3,MIR15A,NEO1,PDCD4,ROCK1,P2RY12,LYPD6,TCIM,NLGN1,ICAM1,IL17F,PIK3CA,CD47,TIAM1,F7,PAFAH1B1,NLE1,RXFP2,OPRK1,OSM,CCL1,SETD4,CUL3,ZNRF1,PIK3R1,LAMTOR2,VEGFA,IL23A,FABP5,PPM1B,FGF23,IL15,TLR1,RPS12,ADRB2,HAND2,RNF167,RNF8,STAT6,CCR7,SEMA5A,CCR6,VAMP8,DKK1,DHX9,COL3A1,CA8,GAS8,TRIM8,EIF2B3,RAB29,LTB,MAP2K3,MIR346,FIS1,LTBR,BECN1,RHEB,SOX9,ANKRD6,CBL,NDFIP1,GHRL,CSNK2A1,PROK1,HCST,IGFBP4,NUCKS1,FCGR1A,MAP2K1,CCR1,DHX15,PELO,ING5,TLR7,FKBP1A,SLC38A9,IL5,STK3,RNF34,OPRM1,MAP3K12,IRF3,BTN2A2,IL6ST,RWDD3,LILRB1,TPD52L1,TEDC2,BCL10,SCG2,IL12A,MIF,CCL3,NUPR1,DUSP19,PPIA,CDC42,IGF1R,FLCN,SFRP1,FERMT2,IFT172,CSNK1E,TLR3,TRIM68,DEFB124,AKAP12,CCL5,MIR146A,CD81,ATP2C1,IGFBP3,CD46,IL4,NPTN,GADD45B,MYD88,SOCS5,HTRA2,STAMBPL1,ING2,CDKN2AIP,RUVBL2,GPR35,LANCL2,MYORG,SWAP70,TMEM101,CSNK1G3,DEPDC1B,MAVS,TYROBP,NCR3LG1,EEF1E1,DOK4,LURAP1,PLG,EMILIN1,TBC1D24,CXCL12,HFE,CLDN4,STUB1,TOP2B,FGF7,PHB1,EDA2R,PDIA3,RUVBL1,SEC13,TESPA1,AVPR1B,MUL1,XCL1,RBPJ,CX3CL1,TNF,FGF3,TWSG1,ACTB,CAMK2N1,MAPKAPK3,CTSD,CSNK2B,AIF1,FOXC2,TIFA,CLDN3,CEBPG,NLRP3,MIR17,MIR214,GJA1,CITED1,NPY5R,GPR89A,CASP4,ILK,TMSB4X,LSM14A,TLR4,RPS15,DLG4,CRBN,PIP4P1,ST3GAL4,ZBED3,HOMER1,HSPA8,PTPN1,LAMB2,GHR,MGMT,MIR26B,ACKR3,ITGAV,TMEM33,NEK7,DDX5,MAP3K3,AVPI1,MIR1-1,TP53,STK4,TNFSF10,FADS2,SDCBP,ACTL6B,SGTA,CD247,F10,MIR212,CXCL13,TNFAIP8L3,IRAK4,SUFU,PPP2R1A,CD3G,TRIM52,KLHL22,MIR198,ATAT1,EIF2B2,B2M,FAF1,SIAH1,TRIM15,TRIM44,CYP27B1,RBCK1,S100B,HMCES,C1QTNF1,HINT1 |
| 3.339e-12 | -26.43 | regulation of epithelial cell migration | biological process | GO:0010632 | 300 | 145 | 18204 | 5365 |
PTN,HBEGF,MIR21,FGFBP1,MIR30A,MIR146A,SP1,MIR149,MIR296,CXCL13,MIR212,PPARG,MIR503,MIR342,TACR1,JUP,MIR31,AAMP,RGCC,GLIPR2,RHOJ,IL4,NR2E1,GAB1,RTN4,MIR193A,EMP2,MIR150,NUS1,MEF2C,MIR29A,MIR210,BMPR2,VEGFA,MIR129-1,MIR204,MECP2,NFE2L2,MIR137,PIK3CG,MIR939,EMC10,KRIT1,VEGFC,KLF4,MIR10A,IQSEC1,SRC,AKT3,MIR132,ANGPT1,FUT1,MIR885,VASH1,FGFR1,ATP5F1A,MMP9,MIR135B,MIR15A,MIR143,HSPB1,MIR379,MIR126,MAP3K3,SYNJ2BP,SVBP,MIR200A,IFNG,FOXP1,MIR133B,ARHGAP5,MACIR,MIR188,CSNK2B,MIR497,MIR492,STAT5A,ARF6,MIRLET7B,TGFBR2,FOXC2,MIR130A,MIR221,GADD45A,MIR206,SOX9,MIR222,PRKCA,PRCP,MET,MIR20A,MIR320A,MIR424,MIR10B,MIR16-1,PRKCE,HDAC5,FGF1,TMSB4X,NRP1,ATP2B4,MIR200C,PTEN,MIR29C,PLG,MIR23A,PROX1,MIR361,GFUS,ADIPOR1,DUSP10,ITGA2,RHOB,SEMA5A,FBXW7,MIR152,HDAC6,EPHA2,AKT1,CD40,STARD13,FGF7,MAPRE2,HMGB1,CORO1C,FGF16,MIR205,MIR495,WNT7A,RAB11A,FGF10,GLUL,ATP5F1B,MAP2K3,MIR24-1,MIR101-1,TGFB2,ROCK2,CALR,MIR640,STC1,SPRED1,MIR505,PDCD10,TNF |
| 3.425e-12 | -26.40 | nuclear protein-containing complex | cellular component | GO:0140513 | 1260 | 476 | 19108 | 5553 |
ELOF1,ANAPC16,RERE,MPHOSPH6,SF3B6,HYAL2,GTF2A1,HDAC11,LMO4,GINS4,CDC5L,SCNM1,SMAD2,MAGOHB,UBE2S,TERC,HCFC2,SNRPD1,PPWD1,PPIL3,TFPT,EAF2,NUP42,BAHD1,DDX39B,LSM6,DDIT3,RNF113A,CD2BP2,MBD3,SLU7,ORC5,LSM4,RFXAP,SMG5,SYNCRIP,TMOD1,TSEN34,CIRBP,HINT1,DHX38,MYBL2,CASC3,BAZ1B,JUNB,SNRNP40,SF3A1,RBM42,TAF5L,MTA3,RRP7A,MIDEAS,COPS4,ZCCHC7,RBM41,IK,NUP107,GINS3,NUP35,POLR3F,CPSF1,USP39,CREB1,SNRNP48,ACTL6A,MED11,CEBPE,LSM3,CBFB,FANCG,PPARG,VDR,MED10,SUPT3H,CHMP4C,ZC3H11A,ESS2,DHX16,PAGR1,PCGF3,TADA3,IVNS1ABP,TRA2A,IMP3,POLR1H,CDK12,ADNP,EZH1,TCEA2,SUGP1,HDAC6,MED21,RBM5,SAP18,RAD1,ATP5F1A,HSPA5,MAD2L2,CFDP1,MED22,PCNA,POLR3B,SNRPA1,HNRNPA1,SMU1,DEK,HR,AKAP17A,DYNLL1,CPSF2,SNRPG,THOC2,SUPT4H1,INO80C,NXT1,TLE1,RFC2,HSP90AB1,ERCC3,BUB3,GTF2H5,NONO,DDX5,NFE2,EZH2,ZMAT2,CDC23,FOSL2,DMAP1,XRCC5,LSM10,DRAP1,DR1,EXOSC3,GTF2F1,CEBPG,MCM4,PABPC1,THRAP3,SNIP1,RAMAC,DHX15,HNRNPA2B1,NABP1,WRAP53,PRIM2,LUC7L3,WDR82,CBX7,CDC20,BIRC5,LGALS3,JUP,EPOP,RBM3,POLR1B,GCFC2,CHTOP,CDK7,RPS3,RUVBL1,SAP30L,POLR2C,SF3B5,BRMS1L,SLX1A,INO80E,NFE2L2,RB1,ATF3,CETN3,PARP11,TENT4A,SSU72,JUN,CBX3,NCKIPSD,SMAD9,MYC,SKP1,KHDC4,POP7,POLR3GL,KPNA1,POLD4,CETN2,RBBP4,HEXIM1,POLA2,FOS,STAT1,APOBEC3G,EXOSC1,SRSF2,TOPBP1,COPS5,MEPCE,UPF3B,MED31,POP5,THOC6,RFX5,PPP1R8,MFAP1,TFIP11,IRF9,ZMAT5,ACTB,GTF2E2,TAF1D,CTNNBIP1,MCM6,HNRNPAB,PWP2,RPP21,NOC4L,GTF2E1,PHF12,RXRG,MAGOH,POLR2B,TNKS,ARMC7,SETD5,PRPF18,SSRP1,APOBEC3F,BCL9,SMARCA5,SMAD1,PHF1,GRAP,PYM1,TAF10,RHEB,DPY30,RBMX2,IMP4,PRPF4,NUP62,NHEJ1,CWC15,ANAPC11,TAF9,GTF2B,MED9,NFYA,MXI1,LSM5,MSH6,ATF1,MED30,CDC40,PHF21A,SNRPB,TAF2,INTS6L,MX2,SMAD4,MED29,NFYB,FAAP100,SNRPN,VPS4B,MED4,MED27,RAD23B,SNRPD2,MORF4L1,CREBZF,ANAPC13,SYNE4,CSNK2A1,GTF2H2,API5,MED23,CDC16,POLR2G,RPA2,S100A10,CDKN1A,TESPA1,BCL7C,RING1,HDAC5,SART3,PTGES3,MPHOSPH10,NBN,ING2,POLE4,CDC26,TAF11,DKC1,MNAT1,MXD1,THOC1,SS18,BRCA1,ZCRB1,EIF4A3,RFXANK,RFC4,FZR1,CHMP1A,CTNNBL1,DDX46,BRD9,PCGF6,ACTL6B,DROSHA,STAT5A,RUNX1,TSEN54,TFDP2,EED,WDR83,POLE3,BICD2,SNRNP70,THOC3,BACH1,TERT,CDC73,MAFG,PRPF19,SNRPE,SAP30,MED17,BAP1,SMARCE1,PAXX,DGCR8,CHMP5,RUVBL2,SCML2,COPS2,ELOC,CDK8,TCEA1,POLR2L,LIG3,POLR3H,ANAPC15,HNRNPH3,LSM8,CHMP1B,CWF19L1,SMAD3,BUD31,LDB1,PHC1,BCCIP,TRA2B,UBE2I,COPS7B,SUPT5H,PPIH,RAN,CBX5,CREB3,E2F6,PCGF2,NUP50,POLR2D,RBBP7,ENY2,MTA2,BCL7B,SUV39H1,SNRPB2,ANAPC4,MCM3,SNRPA,ANAPC2,POLR1D,GTF2F2,GTF2A2,HNRNPF,CHRAC1,TSSC4,TENT2,PIP5K1A,SIN3A,TXNL4A,ATF4,EXOSC4,GLE1,BABAM1,RFC3,SMARCB1,ALYREF,TRIM37,SKIC8,DNTTIP1,GTF2H4,RPA3,PRPF31,NR1H2,CDK2AP2,CSNK1A1,TAF7,CSTF2T,C1D,POLR2I,ORC6,XPOT,MAX,SF3B4,CLP1,SMAD5,PRMT5,SRSF1,CDK9,INTS12,CSNK2B,HSPA8,LSM2,POLR2F,STN1,NFKB1,NFIL3,E2F4,SNRNP27,POLD2,RANBP1,VPS4A,RBBP8,CPSF4,CSTF3,LRWD1,CCNH,PELP1,CXXC1,SMARCD3,ARFGEF1,SNRPD3,CTNNB1,CHMP2A,SF3B1,HNRNPC,STAT6,HNRNPK,SUMO1,TRIP4,WDR3,WDR5B,NUP37,PRDM4,BATF,SEC13,STAT2,WDR6,RFC5,RBM22,FLOT1,PAAF1,BRMS1,HDAC3,NUP153,UTP6,MAD2L1,DDX42,XBP1,COPS7A,HMGA1,NHP2,HLF,NXT2,MED13L,INTS10,DDX23,EXOSC8,ZNHIT1,WDR12,CHMP2B |
| 3.436e-12 | -26.40 | GSPT1 (G1 to S phase transition 1) | protein interactions | 2935 | 294 | 138 | 19454 | 5460 |
RPS16,RPS27L,SYNCRIP,RPL32,RPS2,MAP4,RPL10A,USP15,CRBN,RPL24,BECN1,RPS13,EIF3E,RNASEL,PRDX4,RPL17,SRPRB,ABCE1,RPL23A,RPL3,DHX9,NKRF,ILF2,SAP30L,SRP72,HINFP,TP53,RPSA,IDE,RPL22,COPE,ADRM1,RPL13A,PSMC5,SRP54,EIF2S2,RPS12,RPS20,RPS3,CCNF,CTTN,CHRM4,NAPA,CASC3,UBE2H,EIF3G,ASCC1,SPOP,RPS17,RPL7A,EIF4E,HSPA5,RPS15,RPL4,MTDH,BAP1,RPL27,PPM1G,RPA3,PRKCA,UBE2M,RPL26L1,RPLP0,RPA2,SSR1,RPS14,EGLN3,PAIP1,EIF2S1,DYNC1I2,SNX2,SNX1,SPTAN1,RPLP2,RPLP1,RPL9,RPL8,DRG1,ARMC8,PSMD10,ATG7,HNRNPA1,DNTTIP1,XPO1,EIF3D,PSMD3,PIK3R1,RPL6,RPS4X,PSMD12,HNRNPDL,KRAS,HNRNPF,DHX16,RUVBL1,RUVBL2,RPAP3,RPS24,RPL31,CCT8,PABPC1,RPS11,MOB3C,RPS23,PPP2R1A,RPS7,GTF2E2,KIF2A,EEF2,RPL19,PRRC2A,RPL10,PSMD6,RPL35,FAU,EIF3K,DLST,RPS5,RPS26,RIT1,CCT2,H1-10,RPL39,MCM3,MYC,HNRNPAB,STAU1,MCMBP,BIRC2,RPS28,NUFIP2,EIF4B,PIH1D1,PSMB7,PPP1CB,ETF1,ATP6V1C1,RPL27A |
| 3.549e-12 | -26.36 | regulation of cell motility | biological process | GO:2000145 | 1122 | 435 | 18204 | 5365 |
MMP14,FGR,LDB2,DUOXA2,MIR185,ACVR1C,MIR223,FOXP1,GNRH1,MACIR,PADI2,MMP9,ABHD6,IL6,MIR379,TP53INP1,FUT1,MIR885,CD274,FAM89B,AKT3,PLXNC1,AKT2,DAPK3,VEGFC,EMC10,IQSEC1,MIR449A,OXSR1,MIR10A,TMEM196,MIR204,SIN3A,RIGI,PAX6,TPPP2,NUS1,MIR129-1,MIR210,CD99L2,RGCC,GLIPR2,RTN4,EMP2,PLCB1,MIR519D,MIR21,FGFBP1,CD9,SEMA4C,ELP6,CALR,PIK3R3,SPRED1,PDCD10,SAP30,IGF1,CCL24,HYAL2,TCAF2,RBBP4,IL1B,STARD13,AKT1,FAM107A,WNT7A,PPP3CA,MIR182,LMNA,ITGA2,SEMA3C,MIR92B,CCL28,TIRAP,NRP1,BST2,FGF1,PTEN,JAK2,ATP8A1,SSX2IP,MIR10B,MIR448,PRKCE,GNAI2,KIT,MIR206,LMO4,MET,MIR320A,XBP1,CRKL,MIR492,KIF2A,MSN,MIR497,MIRLET7B,TGFBR2,STK26,PLAA,MIR130A,MIR221,IFNG,ICAM1,BMERB1,F7,CD47,TIAM1,ARHGAP5,MIR15A,MIR143,TACR3,MIR135B,P2RY12,ROCK1,ANGPT1,ZNF609,SRC,DAG1,SST,MMP28,RNF41,PIK3CG,MIR939,THY1,KRIT1,CD200,MIR140,CBLL1,MECP2,FGF23,BMPR1A,MIR137,NFE2L2,ABHD2,CCAR1,NF2,MIR29A,TIMP1,SEMA7A,VEGFA,ADGRG1,BMPR2,IL23A,MTA2,CCL1,BRMS1,PIK3R1,NR2E1,MIR493,MIR551A,FZD4,MIR296,FLRT2,SOX14,NTRK3,MIR218-1,DUSP22,SMAD3,CERS2,MIR24-1,MIR101-1,VSIR,STC1,SELENOK,DUSP1,TMIGD3,MED23,GLUL,TRIM32,CCN3,CD40,CCL23,ACVR1B,TMIGD1,FGF16,MIR205,ADIPOR1,STAP1,CREB3,GFUS,HDAC6,ELP3,NOG,PRR5L,FBXW7,CCL2,SEMG2,CLXN,NHERF1,CCL4L1,PLP1,DRD1,TERT,MIR491,MIR16-1,FUT9,CYP1B1,MIR222,GADD45A,CCDC25,RARRES2,MIR181D,STAT5A,TRIB1,CYRIB,CCL19,DPP4,MIR3173,AKAP12,DEFB124,EPHA4,MIR200A,GPSM3,CCL5,HSPB1,SEMA6C,CDC42,SFRP1,MIR126,IGF1R,TMSB10,FERMT2,CCL17,IL12A,MIR132,DDT,CCL3,MIF,ATP5F1A,CSF2,CAV1,MSTN,ING2,MEF2C,MIR150,SWAP70,MIR31,IL4,MYD88,MIR342,TACR1,HSPA5,LDLRAD4,MIR208A,CD81,MIR146A,PTN,HBEGF,S100A11,CLDN1,IGFBP3,MIR149,UBE2I,IL1A,DUSP3,MAP2K3,TGFB2,ACTA2,DPEP1,NCK1,MIR9-1,TF,ADAMTS1,ATP5F1B,DEFB1,FGF10,COL3A1,WASL,SPINT2,RAP2B,GREM1,TNFSF18,PROX1,ADTRP,CCL20,CFAP20,MIR152,CDH13,CCR7,CCR6,SEMA5A,ACTN4,MIR29C,CD151,CD200R1,ATP2B4,MIR200C,TWIST2,CCR1,HDAC5,SAP30L,CTNNA2,SOX9,TNR,CTNNA1,PRCP,MIR20A,RGN,CCL21,SNAI2,MADCAM1,RRAS2,STK4,SVBP,CLIC4,MIR188,LPAR1,SDC4,MDM2,CXCL8,MIR133B,SDCBP,MIR34A,SOD2,CLEC7A,GPR173,MIR1-1,SYNJ2BP,MAP3K3,MITF,ITGA6,TNFAIP6,CYGB,RAP2C,ADORA3,ADORA1,FGF22,RAC2,VASH1,FGFR1,ITGAV,ACKR3,MPP1,TLR4,CDK6,CCL8,MIR590,CCL11,ST3GAL4,KLF4,ARHGEF39,MKKS,IL34,MIR638,MIR335,LGALS3,AP1AR,OSBPL8,MIRLET7G,AAMP,RHOJ,MIR711,GPNMB,JUP,STK24,MIR193A,CDKN1B,GAB1,RNF20,RAP2A,F10,MIR30A,PTGER4,MIR212,PPARG,MIR503,SP1,CXCL13,ROCK2,MIR640,XCL1,RAF1,MIR1298,CX3CL1,TBCCD1,BRMS1L,RBBP7,MIR505,FGF17,TNF,ADIPOQ,DDRGK1,FGF3,RAB11A,ING1,PRKX,CX3CR1,MIR145,PHACTR1,CDK5,NTNG2,EPHA2,CLDN4,BCL6,CXCL12,FGF7,HMGB1,MAPRE2,CORO1C,MIR495,DUSP10,RHOB,HRAS,MIR23A,PYCARD,PLG,ZNF304,MIR361,AGER,CXCR4,TBC1D24,EMILIN1,TMSB4X,CXCL10,TNFRSF14,MIR424,MIR338,CCL18,LDB1,ACVR1,CCL25,MIR214,CXCR3,CHST2,GJA1,PRKCA,CDH11,CSNK2B,MIEN1,FOXC2,CCR2,AIF1,ARF6,CLDN3 |
| 3.572e-12 | -26.36 | MEN1 (menin 1) | protein interactions | 4221 | 794 | 311 | 19454 | 5460 |
IRF2BPL,MFAP1,USP39,PRDX3,ACTL6A,G3BP2,NOP53,YTHDF1,CCDC86,DCTN3,C1D,HSP90AA1,CD226,RPS29,SMARCE1,PRPF31,RFC5,NOP16,NIBAN2,PRRC2A,RPL19,ERH,RPL7L1,RBBP4,RPL35,MRPL23,RPL37A,SYBU,SNRPD1,CPSF1,GNG12,FAU,SNRPE,RPS11,EXOSC3,RPL29,NUP153,RFC3,SSRP1,RAD21,RFC2,SRSF4,GTF3C3,ZNF592,RBBP7,G3BP1,RPS24,BAG2,SRSF7,SLC39A7,CDKN2C,ATF3,PPAN,SCYL2,RPL23,MPHOSPH6,MRPS26,DROSHA,WDR12,TRA2A,DPY30,PRPF19,PDIA3,DHX15,CETN2,SRSF10,ATXN10,AGK,NOP58,HP1BP3,RPLP2,MRTO4,RPL8,THOC2,RPL9,WTAP,RPLP0,RPL26L1,HSP90B1,MRPS34,DCTN4,SNRPN,SF3A1,RPS14,CXXC1,AATF,NHP2,RPL4,SMC4,GTF2I,B2M,NPM3,MTDH,SQSTM1,PPIH,PRPF4,RPA3,SMAD2,RACGAP1,NONO,RUNX1,RPL26,ZNF687,CDC16,SMAD5,DEK,RPL13A,PNP,RPS20,RPS12,RTRAF,STUB1,PELP1,RAD23B,ILF2,DMAP1,LLPH,SMAD1,RPL15,EXOSC8,CD2BP2,MDC1,SMN1,SNRPG,CTNND1,RPS13,THRAP3,PAK1IP1,RPL23A,ZC3H11A,NKRF,TCOF1,SLC25A10,FOXP1,LRRC8B,MPHOSPH10,NFKB1,MOV10,MRPL24,NOP9,CDK9,TOP1,RPL35A,PWP2,KRR1,EIF4E2,SMAD3,RPL12,HACD3,SRP14,NUFIP2,MRPL12,ZC3H14,PACSIN3,SAP18,FXR2,SRSF2,DDX5,HSPA8,FOS,RPS28,XRCC5,RFC4,POLR1B,THOC6,RCL1,NSA2,RPS26,H2AZ2,FTSJ3,CHTOP,H1-10,KANSL3,HNRNPC,LDHB,PSMA4,MYC,ESR2,RPL10,APEX1,PSMB6,POLR2B,SNRNP40,MATR3,ATP5F1B,CAVIN2,SF3B4,SMU1,DLST,RPS23,RPL18,MTA2,SMARCB1,RPS7,DHX38,PPIL3,TRMT1L,RERE,RPS4X,RPL28,CDCA7L,RUVBL1,ZNF609,ACTR1B,MYO1B,RUVBL2,EWSR1,PABPC1,TOP2B,RPL31,MAGOH,DDX1,CDC23,ARHGAP5,FOSL2,CTNNB1,XPO1,RPL6,PTDSS1,BAZ1B,IFI16,DDX50,PEG10,LYAR,SNRPA1,EIF2S1,FAM98A,WDR82,EED,RBM5,FUBP3,SRSF1,SIN3A,LUC7L3,TFIP11,ZNF326,RPA2,CFTR,TRAM1,GTF3C4,MARS1,RPS15,WDR3,EXOSC4,TWNK,HCFC2,DDX46,RPL27,RBM7,RRP7A,EXOSC1,GEMIN8,RPS17,TIA1,RPL7A,RPF2,SMARCA5,SRPK2,BCCIP,RSL24D1,CSTF3,BUB3,CSNK2B,SEC61A1,QSER1,SF3B6,PSPC1,RPS3,NUPR1,IK,CAPZA2,RBM34,DDX42,TFCP2,TFRC,CBX3,ZMYM3,ZMYM4,ACTR1A,MRPL47,RPSA,TP53,BATF,IMP3,RPL17,CAPZA1,MEPCE,KPNA2,IMP4,H3C1,NUP107,PSMA5,DHX9,RPL3,SLC25A11,RPL10A,NOL12,AKAP8L,RPL24,SNRNP70,SMAD4,CSNK2A1,RBM17,SURF6,DKC1,RPS27L,RPL32,STT3A,SSBP1,RPRM,MRPS9 |
| 3.724e-12 | -26.32 | FBXO7 (F-box protein 7) | protein interactions | 25793 | 589 | 242 | 19454 | 5460 |
STAT6,KLF4,PRKCA,KCNAB1,UBE2M,IDH2,CLIP3,FGFR1,FGF13,NTPCR,HOXB8,HSPA5,TOMM20,SNX33,HNRNPH2,IRF3,LGI1,RBM23,ATP1A1,KCNMA1,CFL1,PRKACB,MED22,MAT2A,AKT3,SLC25A1,PSMB2,RSL24D1,HPF1,PSMC5,PSMA6,RPS3,ACVR1,HADH,RPSA,UBL4A,RPL17,HNRNPK,NEDD8,PDE12,PSMA5,DHX9,PSME1,SLC25A11,GLCE,TMOD2,RPS2,MED27,PSMG2,GAPDH,ELOC,COPS5,CXCL12,EDEM1,ACOT8,MBD5,SNAP25,CXCL9,FMOD,RPS16,CAND1,CDK6,RGS1,SSBP1,PACRG,IL4,TSHR,PSMB3,PAFAH1B1,SHMT1,SAP18,PHB2,UBE2D3,YAF2,DDX5,SNRPA,DNAJB6,RPS26,LRRC20,H2AZ2,CIRBP,BAG3,DRAP1,PSMD1,THAP7,PSMA4,COPS7A,RPL10,APEX1,RORB,PSMB6,MATR3,REEP3,GLRX2,TRIM44,MOB3C,FGF10,TUBB4B,TRAF2,PAK6,RWDD4,RUVBL1,CHCHD2,HNRNPF,PGAP4,PSMA2,PSMA1,PDIA6,TRIM11,RUVBL2,PABPC1,CMTR2,S100B,DDRGK1,XPO1,RPL6,HMG20A,TCP1,MITF,PIGY,TTC9C,PSME2,RPL26L1,ZNF574,MEST,LMNA,UBA52,FUT8,RBFOX2,AATF,POLDIP2,CHMP2B,PRKCB,RPA3,PIM2,YPEL5,XPOT,SKAP2,ATP5F1A,RPL26,BRAP,FBXO7,CSK,TECR,UBB,RPS20,CHCHD6,RPS12,CIB2,STUB1,INPP5K,RNF181,RNF121,CAMK1,GPAM,SOX9,PSMB9,HINT3,VPS16,RNF20,FARSA,DNAJC30,SEM1,HUWE1,CNOT7,TGIF2,SFXN1,ZNF688,PRICKLE2,CRBN,SLC35B3,MPG,NFKB1,MAPRE2,DCUN1D1,PSMB1,OLFM2,MAP2K6,EEF1AKMT3,AIFM1,SLC25A3,APOBEC3C,PSMB7,DUSP22,ATAT1,PPP1CB,RFXANK,WDR77,ALKBH3,NDE1,SKP1,PSMC1,SPATA4,SRM,CCDC186,NSFL1C,PSMA3,BIRC2,EXD2,HSP90AA1,PPP1R17,FYTTD1,SAMHD1,PRPF31,RNF40,PNOC,REEP4,RBBP4,EIF4A2,RPL37A,GLIPR2,TENT5D,RPS11,IL7,RPN1,MAPK10,PPP2R1A,CSNK1E,COPS4,FLOT1,RPS24,BAG2,SRSF7,AKAP14,BCKDK,HSPD1,SLC25A5,RPL23,VCPIP1,UBE2D1,ATG7,SLC25A26,UBXN6,PSMD3,TMEM237,SRSF10,CACYBP,COPS7B,COPS2,PSMB4,PSMB5,WDR6 |
| 3.744e-12 | -26.31 | MARS1 (methionyl-tRNA synthetase 1) | protein interactions | 4141 | 327 | 150 | 19454 | 5460 |
RIGI,MIR16-2,MIRLET7C,FBXO25,HUWE1,MIR9-3,HAPSTR1,TCOF1,MIR200A,CASK,MIR20A,TFCP2,MIR17,MIR200C,MIR15A,TP53,COMTD1,CDK9,TMPO,MIR429,MIRLET7G,FZR1,PLEKHF2,RPS16,MIR25,MIR106B,MIR34A,MAP4,DPP4,KARS1,MIR107,HSPA5,MIR29A,MIR7-3,FBXW7,MIR34C,RNF113A,MIRLET7I,PML,MIR205,BAP1,SNAPC1,MIR10B,RPA3,MIR7-1,ACACA,MIR21,OXSR1,HEXIM1,RPLP0,RARS1,ZCCHC17,HSP90B1,GRM2,RPA2,SDCBP,CFTR,MIR1-2,CAPN1,ARHGAP1,EEF1E1,ATG16L1,MIR34B,VIRMA,SMURF1,ACAT1,MSN,PSPC1,CCNF,UBE2H,MIR145,USP14,MAT2A,AP1M1,XPNPEP1,MIR155,G3BP1,EMC8,KRAS,TMEM147,SCPEP1,MIR206,MIR9-2,PABPC1,CCT8,MOB3C,PDHA1,CHMP4C,PLS3,ISG15,GFPT1,PPP2R1A,HEXA,B3GNT2,DHX15,TRMT61A,MIR9-1,SUMO2,HNRNPL,EIF2S1,MIR214,MIR141,PSMB5,MIR7-2,PHB1,MIR140,MIR221,MIR1-1,RB1CC1,MIR31,AGR2,PSMD10,DDRGK1,ATG7,XPO1,MIR29C,MIR143,WWP2,PRPF19,IFI16,G3BP2,MIR106A,STAU1,EP300,HDAC5,CRY1,PIH1D1,CSNK1A1,EMC9,RPL27A,PRKAB1,ESR2,MIRLET7D,RPL35,FBXO22,MIRLET7B,RAN,DLST,LMBR1L,TRMT6,RIT1,ILK,MIR363,DCAF4,BRCA1,MIR98,CUL2,PSMA4,CUL3,MYC |
| 3.989e-12 | -26.25 | GTP hydrolysis and joining of the 60S ribosomal subunit | REACTOME pathways | R-HSA-72706 | 117 | 73 | 10285 | 3229 |
RPL12,EIF3J,EIF3D,RPL18,RPL31,RPL9,RPL17,EIF3G,RPS3,RPL22,EIF2S2,EIF3E,RPL19,EIF4E,RPL26L1,RPL35,RPL10,RPL29,RPL10A,RPS15,RPL23,RPL39,RPS10,RPS7,RPS27L,RPL26,RPS11,RPS23,RPS2,RPL27,RPS12,RPL4,RPL7,UBA52,RPS9,RPL37A,RPS20,RPL6,RPSA,RPL3,RPL32,EIF5B,FAU,EIF4A2,RPS24,RPS16,RPL24,RPL35A,EIF4B,RPS14,RPL23A,RPL7A,RPL28,EIF3K,RPL8,RPS5,RPLP2,RPS17,RPS28,EIF1AX,RPL15,RPS26,RPS29,EIF2S1,RPL13A,RPLP0,RPS4X,RPLP1,EIF4H,RPL27A,RPS27A,RPS13,RPL10L |
| 3.989e-12 | -26.25 | L13a-mediated translational silencing of Ceruloplasmin expression | REACTOME pathways | R-HSA-156827 | 117 | 73 | 10285 | 3229 |
RPL37A,RPS9,RPL7,UBA52,RPL4,RPS2,RPL27,RPS12,RPS23,RPS11,RPS7,RPS27L,RPL26,RPS10,RPL39,RPL23,RPS15,RPL10A,RPL29,PABPC1,RPL35,RPL10,RPL26L1,EIF4E,RPL19,EIF3E,RPL22,EIF2S2,EIF3G,RPS3,RPL17,RPL18,RPL9,RPL31,EIF3D,EIF3J,RPL12,RPL10L,RPS13,RPS27A,EIF4H,RPL27A,RPS4X,RPLP1,RPLP0,RPS29,EIF2S1,RPL13A,RPL15,RPS26,RPS28,EIF1AX,RPS17,RPLP2,RPS5,RPL8,RPL28,EIF3K,RPL7A,RPL23A,RPS14,EIF4B,RPL35A,RPL24,RPS16,RPS24,EIF4A2,RPL32,FAU,RPL3,RPSA,RPL6,RPS20 |
| 4.051e-12 | -26.23 | ILF2 (interleukin enhancer binding factor 2) | protein interactions | 3608 | 566 | 234 | 19454 | 5460 |
PRPF19,PIK3R1,HNRNPA1,HNRNPD,MRPS26,RPL23,DICER1,MPHOSPH6,RPL8,RPL9,PHB1,IFIT2,RPL7,SPTAN1,SRSF10,NTMT1,DHX15,CSF2,WDR44,RAF1,ZNF263,ACTN4,EZH2,CHMP4C,PPID,HNRNPA2B1,RPS24,SRSF7,MCM6,SSRP1,CUL3,CUL2,MCM4,MCM3,RHOB,BRCA1,SCFD1,RIT1,CPSF1,ZNF22,SNRPD2,SNRPD1,RPS9,SEC61B,MRPL23,LAMTOR3,ACTB,GGPS1,RPL19,WDR77,TIMM13,PPARG,BIRC2,UCHL3,UNC45A,GRSF1,MOV10,HDAC6,APOBEC3F,MFN1,CRBN,CTDSPL2,RCHY1,DCUN1D1,TOP1,EIF2B2,MRPL50,CDK9,CWC15,MRPL24,FBP1,LBR,EEF1A1,RPL15,EXOSC8,SRP72,SFXN1,RPL23A,SNAP23,HSD17B10,PC,HUWE1,RPS13,MDC1,AR,IVNS1ABP,CASC3,CCNF,EIF2AK2,EIF4A3,RTRAF,PRKRA,TRIM27,TRIM24,PTEN,RPS20,SFXN2,YES1,VIRMA,ATG16L1,JUP,MRPS34,LMNA,GRM2,METTL14,RPL26L1,RPLP0,RPA3,SOD1,SIRT7,SQSTM1,MRPL17,RPL4,FBXW7,BRIX1,IFI16,WWP2,RPL6,CPEB1,DDRGK1,AGR2,POU5F1,DDX1,DRG1,MAGOH,SRSF1,EED,PAIP1,EIF2S1,HNRNPL,SNRPA1,LYAR,SNRPD3,SUPT5H,SOX2,PDHA1,RPS23,RPL18,RPL31,RBM3,PABPC1,ABCF1,RUVBL2,PICK1,EWSR1,RTCB,KRAS,VDAC1,RPS4X,CBLL1,HNRNPDL,MYC,APOBEC3B,HNRNPAB,HNRNPC,PRMT6,BTF3,SNRPB,FTSJ3,PSMD14,OSGEP,ICAM1,RPS26,TRIM44,DLST,CMTR1,SF3B4,MATR3,RPL10,TOMM22,PIH1D1,RFC4,SNRPA,XRCC5,HSPA8,SF3B1,HDAC5,EP300,DDX5,UFL1,EMC1,TRA2B,SRSF2,STAU1,EEF1G,COPS5,GAPDH,SNRNP70,RPS2,RPL10A,SYNCRIP,ALYREF,RAP1B,RPS16,CAND1,FZR1,RBM42,TMPO,CDC5L,UBL4A,STRBP,KIF1C,DUSP1,H2AX,TFCP2,DNAJC2,DHX9,NEDD8,CDC40,IMP4,MEPCE,RPL17,RPF2,RPL7A,SPOP,RC3H2,IGF2BP1,ELAVL2,UBE2H,RPS3,PSPC1,MRPS28,EIF2S2,KCTD9,AGO1,RPA2,EIF2B3,ZNF326,HEXIM1,KLF4,BAP1,CWF19L1,METTL22,HSPA5 |
| 4.110e-12 | -26.22 | RPS7 (ribosomal protein S7) | protein interactions | 6201 | 394 | 174 | 19454 | 5460 |
EIF3G,SPOP,RC3H2,ATP1A1,RRP7A,UBE2H,RPL7A,RPS17,AR,PPP1CC,NDN,RPL10L,RPL13A,RPL22,VIRMA,RPS3,PSPC1,CCNF,METAP2,FGFBP1,RPS12,RPS20,LMNA,RPA2,METTL14,WWP1,UBE2M,HEXIM1,RPL26L1,RPLP0,ATG16L1,RPS14,PSMC4,TPT1,UBA52,CFTR,RPS15,NF2,PIK3R2,RPL4,FBXW7,PIAS1,BRIX1,HSPA5,RPL27,BAP1,RPA3,PNO1,SIRT7,PML,SQSTM1,SNRNP70,MPHOSPH10,RPL24,H2AC4,RPS2,RPL10A,ENY2,KXD1,EMC4,CDC37L1,COPS5,HDAC6,ARF6,FZR1,RPS16,CAND1,RPS27L,RBM42,CDK9,MDM2,ZBTB2,RPL12,KRR1,RCHY1,TFCP2,DISC1,DNAJC2,IK,SRP72,UBL4A,RPSA,TP53,RPL15,HUWE1,HNRNPK,NOC4L,VRK1,RPS13,MEPCE,RPL23A,RPL3,BRCA1,COP1,RPS5,RPS26,RIT1,MYC,CUL3,BTF3,RPS29,LAMTOR3,RPL35,MAD2L2,RPL10,RPL19,FAU,CMTR1,CYB5R3,SNRPD1,RPL37A,SEC61B,RPS9,EMC9,EIF4B,PIH1D1,RPL27A,MTF1,FBXO42,ETF1,UFL1,G3BP2,PYM1,DDX39B,RPS28,HSPA8,YAF2,DDX23,AGR2,AHSA1,POU5F1,DRG1,RPL23,WWP2,RPL6,YWHAG,XPO1,HNRNPA1,DDRGK1,RPS10,NOP58,BUD31,RPL7,RPL9,FOLR1,RPL8,PHB1,EED,RPLP2,SPINT2,RPLP1,EZH2,NGB,RPS11,RPL18,RPS23,B3GNT2,NCSTN,EEF2,G3BP1,KRAS,EMC8,TRIM26,RBBP7,TRIM37,ZBTB14,RPS4X,RAD21,HNRNPDL,RPL31,GADD45A,HNRNPA2B1,RTCB,RPS24 |
| 4.163e-12 | -26.20 | RPL8 (ribosomal protein L8) | protein interactions | 6132 | 485 | 206 | 19454 | 5460 |
RPS14,CDK7,METTL14,MACROH2A2,RPLP0,RPL26L1,SIRT7,RPA3,KIN,FBXW7,HMGB1,RPL4,NPM3,NF2,BRIX1,UTP23,AATF,PPP1CC,TUFM,RPL26,DNAJC19,METAP2,EIF4A3,CCNF,UBE2I,RPS20,PRKRA,RPL13A,NDN,RPL22,FBP1,RPL15,TAF1D,AURKAIP1,SRP72,ILF2,NKRF,FAF1,RPL23A,VRK1,HUWE1,PAK1IP1,RPS13,SPATS2L,HDAC6,MPHOSPH10,RCHY1,RPL12,RPL35A,MRPL24,WDR77,NUDT3,EMC9,CCDC86,NMRAL1,NOP53,G3BP2,CUL2,CUL3,RPS29,ZNF668,BRCA1,RIT1,RPS5,RPS9,SEC61B,RPL37A,RPL7L1,RPL35,RPF1,MRPL23,RPL19,B3GNT2,RPL29,MAK16,CHMP4C,EZH2,RPS11,TRIP4,RPS24,TRIM37,G3BP1,SAR1B,MAP3K14,KDM2A,RPL23,BCL2L1,RB1CC1,RSBN1L,PHB1,FOLR1,RPL9,RPLP2,RPL7,CFTR,RPA2,ZNF770,ARL15,UBE2M,HEXIM1,PML,RPL27,BAP1,RNF113A,DPH3,RPS15,HSPA5,RPL7A,RPF2,RPS17,TRIM23,RC3H2,MECP2,UBE2H,RPS3,PSPC1,RBMX2,FGFBP1,RPL10L,RSL24D1,TP53,RPSA,UBL4A,H2AX,DNAJC2,RBM34,MINDY3,RPL3,CHDH,IMP4,TGFBR2,NEDD8,H3C1,RPL17,MEPCE,ENY2,API5,CSNK2A1,COPS5,RPL24,SNRNP70,RPL10A,RPS2,NOL12,RPL32,SPPL3,DNAJC1,CAND1,RPS16,SURF6,RBM42,TMPO,DKC1,FBXO42,MTF1,RPL27A,MAP2K1,PIH1D1,NUFIP2,SPECC1L,HSPA8,EEF1G,STAU1,UFL1,MRPS7,SFN,MYC,BTF3,ATG3,FTSJ3,NSA2,H1-1,ICAM1,RPS26,ZCCHC7,MATR3,RPL10,ESR2,MED9,RPS7,SOX2,DNAJC25,TUBB4B,CSTPP1,RPL18,RPS23,RPL31,EWSR1,HMGN4,KRAS,RPL28,RPS4X,RIOX2,RPL6,WWP2,DDX50,IFI16,DDRGK1,CTNNB1,XPO1,AGR2,DRG1,MAGOH,SRSF1,EED,RPS10 |
| 4.449e-12 | -26.14 | regulation of molecular function | biological process | GO:0065009 | 2005 | 725 | 18204 | 5365 |
DISC1,CHI3L1,TAFA1,TESK1,CHN2,CRADD,TERT,NFKB1,CCL4L1,SRI,FGF13,NEK2,PLN,GSKIP,NLGN2,TRAF6,GADD45A,UBLCP1,CAMK2N2,CCNF,GRM2,CCL19,MIR378A,TRIB1,IFIT2,SMAD3,CRTC2,MIR24-1,ISCU,DUSP22,CRHBP,WNT2,HNRNPD,RAP1A,SERPINB1,CLTRN,TMIGD3,TRIM62,TFRC,CLU,MIR205,RALB,CCL23,OTULIN,NFKBIL1,NKX3-1,RPS7,FCGR2B,STK38,COX17,SMARCB1,UBASH3B,BRMS1,GSTO1,IFI16,NTRK3,NTRK2,TFIP11,RGP1,CTNNBIP1,NBN,MIR153-1,TCEAL7,MIR34B,MIR873,IFNG,TAB2,LGR4,PTGES3,FAM162A,NME1,ADRA1A,SRC,SH3BP4,STAC3,ANGPT1,SERPINH1,PHB2,PSEN2,PLCB2,HEXIM1,CD200,TRIM21,LEP,HNRNPK,COMMD6,BCL2L1,PTEN,JAK2,PKIB,CAND1,TIRAP,LRP6,RAMP3,DVL2,GSK3A,FGD2,BAD,DEFB114,ABCE1,CREBZF,HPF1,ADRB3,LMO4,ODAM,EIF2AK2,RLN2,GNAI2,ARRDC3,CDK12,PLAA,SKP1,TOR1AIP2,ATP5IF1,CARTPT,UBE2N,SLC8A1,DIRAS2,EP300,RFC3,PDCD10,EIF3D,BOK,CTSK,HYAL2,CCNI,CCL24,GPX1,CYFIP2,DPH3,UBE2V1,GMNN,TNFSF15,SERPIND1,TBC1D4,MIR92B,KHDC1,TANK,ARHGAP15,DRD3,BCL2A1,SERPINB9,VAV2,PMAIP1,SNAPIN,MIR210,MIR129-1,MIR33B,NOS1AP,RGS10,EMP2,RGCC,CPNE1,CACNG3,MIR21,RPS2,YWHAG,FGR,LDB2,IL12B,ERP29,SERPINA1,GTF2F1,DLGAP4,TRIM34,MIR186,PPP1R17,JUN,HSPD1,USP6NL,NEUROD2,EEF1A1,FLOT1,PPARA,SERPINA5,VAMP2,PSMD10,TBC1D13,ZNF593,RFC4,HSP90B1,JPH4,SPHK2,ZNF622,SPINDOC,DAP,STRADB,CFTR,TBC1D17,DDR1,SCN2B,AZIN2,PSME1,LDB1,TBC1D5,F2,CCR2,PLSCR1,CAPN1,MAP3K11,DDRGK1,ZC3H15,ADIPOQ,TBC1D1,RAF1,CACNB3,IL10,ROCK2,RFC5,CDKN2C,TRAF1,TRAF2,TRIM6,RPS3,PPP1R1B,HMGB1,MAPRE2,CORO1C,MIR495,DFFA,FEM1A,EPHA2,RGS2,BCCIP,S100A10,CAB39,PYCARD,HRAS,AGER,SERPINA3,EPO,IKBKB,IL34,GAPDH,AGAP1,ESR2,FZD6,NCSTN,ITK,EZH2,CHRNA7,GABARAPL2,PRKCQ,MIR711,JUP,PPARG,CCDC22,CCNA2,RPL23,PAQR3,SFRP4,MIR133B,CCNY,RGS1,DIPK2A,TAF7,LPAR1,SVBP,SPPL3,SCN1B,ITGA6,CLEC7A,MIR34A,TSHR,FGFR1,PSENEN,PTPRQ,ADORA3,CCL11,NETO1,MIR590,CCL8,DDIT3,TRIM27,ATP2B4,MIR200C,CCT2,MMD,MAD2L1,ACTN4,CAV2,MACROH2A1,AHSA1,SUMO1,COPS5,CRHR1,DIRAS3,OAS1,ARHGAP25,TRIM22,MIR20A,CCL21,CSTA,ATP1B1,CSTB,ATP1A2,HSPE1,DBNDD1,IL1A,TGFB2,CHP1,MIR144,FGF10,PCNA,RAP2B,TRIM37,SOX2,PTPN22,GSTM2,MIR152,TNFSF18,PROX1,CCL20,MTDH,GREM1,CAV1,TAB1,TNKS,VCPKMT,FKBP1B,CDKN2D,TAX1BP1,NDUFA4,AGAP2,HSP90AB1,MEF2C,CAV3,PKIG,MIR208A,GFI1,SLPI,CYP2D6,SMAD2,IFT57,SERPINB6,BUD31,UBE2I,IDE,SNRNP70,TRIM26,CD4,RPS27L,LILRB4,PSEN1,ARL6IP5,PPP1R2,LRRC14,WWP2,MYC,ATP1B3,CDC20,DAPK1,HSPB1,PRDX3,PDCD5,PSRC1,INPP5K,HTR2A,RPS6KA4,SSBP1,SOCS4,HSP90AA1,CDK5R1,FGF12,NHERF1,CCL2,SYNGR3,SEMG2,JMJD8,MAPKAPK5,PIH1D1,DRD1,MIR16-1,CHRM3,CACNB4,CLEC12B,CCNH,TLR2,CYP1B1,DIRAS1,P2RY11,XRCC5,PPIF,VSIR,SCN3B,MIR101-1,UBE2L3,TRIM32,VMP1,SERTAD1,LAMP3,EGLN3,DUSP1,BIRC2,SYK,FGF16,NLRP1,CD40,ARFGEF1,TMBIM6,FBXW7,HDAC6,S100A8,MIR208B,TESC,NOG,STK11,CCAR2,TRIM5,FGF23,EIF3E,PRELID1,MTPN,RALGAPA2,IL23A,VEGFA,RGS6,CEP85,FXYD6,TIMP1,PRRT1,METTL21A,RAN,NR0B1,CCL1,TCP1,MIR218-1,FZD4,STIM1,NIBAN2,CCNB1,RXFP2,CAMK1,CACNB2,NOSIP,TIAM1,ZC4H2,TNNT2,NLGN1,TCIM,SERPINB11,ROCK1,PDCD4,CACUL1,GPIHBP1,SERINC1,MIR15A,SERPINI1,IL18,CHTOP,WRAP53,THY1,PIK3CG,HNRNPA2B1,MIR140,FASLG,CD40LG,PIP5K1A,KCNS1,TSG101,FGF1,NR1H2,PLA2G5,PCSK9,CDK5RAP3,PSMA3,PRKCE,MIR448,MET,EIF4A2,PATE4,FAS,ANP32B,KIT,CCND1,CAAP1,TGFBR2,MIRLET7B,MSH6,PAK2,AR,SOD1,DKC1,NFKBIA,APH1A,IGF1,SPRED1,SNX18,ABCB1,TAX1BP3,GH1,TNFAIP3,GSTP1,VDR,TCAF2,TXN,BAK1,MT3,CCND3,AKT1,AIFM1,SIAH2,IL1B,SLCO3A1,TLR6,DNAJC24,MAD2L2,GPR65,PAX6,SIPA1L1,EDNRA,FOXS1,DSTYK,LPAR2,CNRIP1,HP,ANXA4,NUS1,PRKAG1,TLR9,PPP2R5A,SMG8,MIR148A,MCL1,SFN,DNAJB6,LCP2,CDKN3,SELENON,UBE2S,DNAJB2,MAGEC2,G3BP2,ACVR1C,TBC1D25,BAX,TOM1L1,AHCYL1,IL6,GNAQ,PYDC2,CD86,MMP9,PPP1R12A,PPP2CB,PSMA6,PLXNC1,FOXP3,ERRFI1,MIR130B,PRNP,BVES,OXSR1,SPRY1,TMBIM1,TMSB4X,MDFI,CDKN1A,CCL18,TBC1D10C,NLRP2,GREM2,RB1,MIR17,YWHAB,NLRP3,CCL25,CEBPG,CLDN3,NHEJ1,TBC1D16,CSNK2B,NEUROG2,CTSD,LYNX1,ACTB,CAMK2N1,TNF,CX3CL1,MUL1,XCL1,AVPR1B,MID1IP1,EDA2R,PHB1,RANGRF,DNAJC10,HFE,CLDN4,HEXIM2,ARHGAP12,HECW1,PKIA,IL1RAP,DUSP10,LGALS3,RBCK1,CYP27B1,TRIM15,APOC2,FAF1,PSMB9,B2M,PRIM2,TRIM52,CDKN1B,RHOG,SUFU,UFL1,CXCL13,MIR212,PSME2,CAP2,TNFSF10,SUMO3,GNAI3,STK4,TP53,HPCA,MIR1-1,NEK7,POR,ITGAV,MIR26B,TIMP4,GHR,BAG2,PTPN1,RAP2C,HOMER1,SPTSSB,KLF4,DLG4,IFI6,TLR4,RASGRP2,EDF1,CTTNBP2NL,MIR29C,FKBP1A,MIR339,SLMAP,KDM1A,HGS,KCNIP2,PRMT2,MAP2K1,HDAC5,NUCKS1,FCGR1A,CSNK2A1,RGN,S1PR4,NDFIP1,CBL,TOPORS,FIS1,BANF1,DLG1,DLG3,IGBP1,DPEP1,PARM1,DUSP3,GTF2B,MAP2K3,MIR192,ADD1,MIR9-1,TRIM8,GAS8,RFC2,MIR30D,DHX9,SPOCK1,DKK1,PKP4,FEM1B,CCR7,C9orf72,BHLHE40,HAND2,ADRB2,CLIC2,KCNAB1,MAVS,FURIN,GPR35,EFNA5,HTRA2,SOCS5,MYD88,SERPINB10,IL4,FXN,ADD2,CST3,EFNA3,CCL5,EPHA4,TLR3,TRIM68,MMUT,CSNK1E,FERMT2,TIMP3,CCL17,SFRP1,IGF1R,RTRAF,PPIA,FZR1,DUSP19,NUPR1,ID1,YWHAH,CCL3,BCL10,TPD52L1,RWDD3,HEY2,MAP3K12,OPRM1,RNF34,STK3 |
| 4.526e-12 | -26.12 | ORF1ab (ORF1a polyprotein;ORF1ab polyprotein) | protein interactions | 1489680 | 640 | 259 | 19454 | 5460 |
CCDC86,POLA2,G3BP2,ATP6V1G1,TMEM231,MTX2,PGRMC1,CA12,LARP4B,IFTAP,FKBP1A,GNG12,WNT10B,CYB5R3,EIF3K,AP2M1,SPINDOC,TSN,ACTB,PRRC2A,B4GAT1,ACO2,USP13,PYCR1,CUL2,MYO6,RPS5,SP1,HSPD1,NEK9,SLC25A5,ATF3,MAEA,ZC3H7A,PCNA,BAG2,LASP1,G3BP1,ATP5F1D,COPS4,HS2ST1,RFC2,FAF2,ERLIN2,IFNGR1,EXOSC3,BZW2,RPS11,PLD3,SP2,PHB1,OCIAD2,MAP1LC3A,CETN3,KRT8,SPTAN1,PPIA,ERLIN1,HSBP1,IFIH1,STOML2,EIF3D,KDM2A,TMEM30A,AHSA1,RB1CC1,RPL23,COTL1,PRIM2,GID8,SYVN1,SPCS2,SQSTM1,PPIH,YKT6,DAD1,CHMP2B,AATF,SS18,POLDIP2,WDR83,SLC35E1,EIF3J,LMNA,HSP90B1,MET,OXSR1,KRT7,TMOD1,MACROH2A2,ENO1,MSN,ACAT1,UBASH3B,ABHD17A,MGST3,DDAH2,PDCD5,PYCR2,ATP5F1A,NONO,LGALS8,CCHCR1,YPEL5,PPIG,ANKIB1,TCOF1,EMC2,TOM1,APH1A,EIF3E,TBK1,MRPL11,ALG11,MAP1LC3B,LBR,SLC29A1,MAP2K3,EXOSC8,NRM,ADAMTS1,POLR2G,SRP72,HACD3,RCHY1,EIF4E2,RB1,CHID1,TES,CD151,ARF6,SLC25A17,MSMO1,TMEM199,TLE1,HDAC6,ATP1B1,POR,MPHOSPH10,C1GALT1C1,SLU7,JAKMIP1,TMEM106B,APPBP2,DDX5,RNF5,PHB2,RANBP10,CERS6,LAP3,TOM1L2,SIGMAR1,EIF4B,NCOA5,CAV2,CDC42EP3,CMTR1,GTF2F2,PSMD4,TAX1BP1,TIMM21,POLR2B,PSMA4,BTF3,SLC1A3,COX16,SERPINH1,MDH1,RPL31,PGAP4,ZNF609,VDAC1,PFDN1,CCAR1,HNRNPDL,IMPA2,NETO2,PPIL3,NCSTN,ISG15,DIRAS1,TUBB4B,KDELR1,SMARCB1,SWAP70,RBM5,PRCC,ANXA4,MAGED2,SPINT2,FAHD1,DYNC1I2,PEG10,RPL6,PFDN5,PPIB,PPFIBP1,NGDN,EXOC1,DDX1,ANKRD50,BAP1,PML,IRF3,LCP1,DERL1,PRDX6,SPTBN1,GALNT1,SYS1,HECTD1,RPS3,UQCRC2,CREB1,TRAF7,GPX1,CTSB,SC5D,IDE,SLC25A1,CFL1,CHPF,EIF3G,NAE1,ATP5PF,RBM41,YIF1A,AKAP12,NEDD8,NUP107,SNRNP48,PSMA5,TOLLIP,TMEM33,HNRNPK,SRPRB,MEPCE,MNAT1,SEPHS1,TNRC6C,RPSA,FAM162A,YIPF4,ZNF581,SURF4,RNF8,SLC25A24,MRPS9,RNF128,ARL4D,RPS16,DNAJC1,PLG,CDC5L,SELENOS,PLEKHO1,SMCHD1,RPS2,ATP6V1D |
| 4.622e-12 | -26.10 | DIABLO (diablo IAP-binding mitochondrial protein) | protein interactions | 56616 | 268 | 128 | 19454 | 5460 |
SYP,DNAJC10,CHCHD4,PDCD4,UBE2H,MLF1,NAA50,NDUFB10,CEP85,DNAJC5,GABPA,TRAF1,APOC4,CHCHD6,SAMM50,DYRK2,TIMMDC1,NDUFAB1,YKT6,UBE2K,GRPEL1,DDX46,GID4,TMX2,HNRNPH2,MAVS,GPX4,AREL1,COX5A,GMPPB,DNAJB2,DERL2,TOMM70,SLC25A12,TIMM8B,AIFM1,EIF4E2,COX4I1,HSD17B11,GPD2,NDUFS3,ACTR2,MLLT11,BIRC5,UBL4A,MMP20,TBK1,SNAP29,EEF1A1,DDX39A,TIMM8A,TOLLIP,POLE4,FAF1,LTBR,SFXN1,ABCE1,CLPB,TMX3,BEX3,MYO6,YWHAZ,BRCA1,PFDN4,HSP90AA1,DHRS1,HTRA2,USP13,COX6B1,LDHB,CUL3,PMPCA,TOMM40,CXCL1,SLC1A3,MLF2,RANBP6,TAB1,RPF1,DYNLL1,CHCHD3,NCKAP1,SURF2,DLST,APOC2,CAV2,NDUFA5,TOMM22,MTX2,TANK,AGTRAP,TIMM13,SEC22A,TOM1L2,DUSP22,PHB2,PSMC1,GINS3,RNF41,ATP2C1,CD40,EXD2,BIRC2,TRAF6,HAX1,ARMC8,STOML2,ATG7,YWHAG,YWHAH,EXOC1,COPS7B,ATXN10,NDUFS8,NUF2,PHB1,SLC66A2,TRAF2,UFM1,CCAR1,DMPK,RERE,TOMM6,FLOT1,SSRP1,CDK5,MYO1B,MKLN1 |
| 4.636e-12 | -26.10 | cytosolic ribosome | cellular component | GO:0022626 | 115 | 69 | 19108 | 5553 |
RPS29,RPL26L1,RPS11,ABCE1,RPLP1,RNF10,RPL39,RPL19,RPS9,RPS27A,RPL9,RPL32,RPL27,ZCCHC17,EIF2D,ETF1,RPL31,RPL10L,UBA52,RPS4X,RPL35,RPL37A,RPL28,RPL7,RPS13,RPS24,RPL23A,RPLP2,RNF14,RPS17,RPL13A,RPL17,EEF1A1,RPL24,RPL26,RPS15,RPL7L1,RPS5,RPS3,RPL23,RPL35A,RPL3,RPL27A,PELO,RPS20,RPL4,RPL15,RPSA,RPS14,RPS16,RPL12,RPS27L,RPL7A,RPS12,RPL22,RPL10A,RPS10,RPL29,RPL8,RPS23,RPL6,RPL10,RPS28,RPS7,RPLP0,RPS2,RPL18,FAU,RPS26 |
| 4.698e-12 | -26.08 | Eukaryotic Translation Termination | REACTOME pathways | R-HSA-72764 | 96 | 63 | 10285 | 3229 |
RPL18,RPL9,RPL31,TRMT112,RPL12,RPL26L1,RPL10,RPL35,RPL19,RPL22,RPL17,RPS3,RPS27L,RPL26,RPS7,RPL39,RPS10,RPL23,RPS15,RPL29,RPL10A,RPL37A,UBA52,RPL7,RPS9,RPL27,RPS2,RPS12,RPL4,RPS11,RPS23,RPS24,RPS16,RPL3,RPL32,FAU,RPSA,RPL6,RPS20,RPL23A,RPL28,RPL7A,RPS14,RPL35A,RPL24,RPL15,RPS26,RPS17,RPS28,ETF1,RPLP2,RPL8,RPS5,RPS13,RPL10L,APEH,RPL27A,RPS27A,RPS4X,RPLP1,RPS29,RPL13A,RPLP0 |
| 4.886e-12 | -26.04 | RPL26 (ribosomal protein L26) | protein interactions | 6154 | 350 | 158 | 19454 | 5460 |
RPL37A,MRPL13,RPS9,ZNF22,ZNF189,CMTR1,CBX5,RPL19,RPL10,MAD2L2,TRIM29,RPL35,RPF1,BTF3,MRPL16,THAP7,RPS29,MYC,SFN,CUL3,NOP16,ICAM1,RPS26,RPS5,RIT1,DNAJB6,H1-1,NSA2,ZCRB1,DCAF4,ATG3,HSPA8,SF3B1,NGRN,MRPS7,UFL1,STAU1,H1-5,WDR77,PAFAH1B1,PIH1D1,HP1BP3,RPLP2,RPL8,FOLR1,PHB1,SRSF10,RPL7,MRPL9,YWHAG,HNRNPA1,DDRGK1,RPL6,WWP2,MRPS35,RPL23,MAGOH,ZCCHC9,MRPS11,RPL31,RPS4X,RPS27A,RBBP7,TRIM26,KRAS,TNF,TRIM37,SOX2,B3GNT2,RPS11,RPL18,EZH2,CHMP4C,NGB,FGFBP1,PRKRA,SEC61A1,PTEN,CCNF,PELP1,RPS3,EIF4A3,RPL22,RPL13A,FBXO7,PPP1CC,RPL7A,UBE2H,ATP1B3,SAYSD1,RNF113A,RPA3,BAP1,RPL27,PML,SIRT7,AATF,BRIX1,MRPL20,RPS15,HMGB1,RPL4,KLF12,RPS14,EEF1E1,HEXIM1,RPLP0,RPL26L1,ZNF574,UBE2M,MACROH2A2,KLF4,RPA2,GRM2,METTL14,PRR3,RPL32,RCHY1,KRR1,MDM2,DKC1,MRPL24,ZBTB2,MRPS23,CAND1,RPS16,FZR1,MRPL50,HDAC6,E4F1,ATP1B1,MOV10,CMSS1,RPS2,USP15,CRBN,TUBG1,RPL24,SNRNP70,RPL3,MRPS18C,MEPCE,SRSF12,RPS13,MRPL22,RPL17,MRPS33,VRK1,IMP4,H2AX,RPL15,UBL4A,FBP1,RPSA,MRPL47,TP53,MRPL49,MRPL51 |
| 4.944e-12 | -26.03 | RAB5A (RAB5A, member RAS oncogene family) | protein interactions | 5868 | 679 | 272 | 19454 | 5460 |
SNX5,ATP1A1,EIF3G,GORASP2,SMARCA5,RAB2A,ROCK1,CHMP5,STX10,EPCAM,NECTIN2,UQCRC2,LEMD3,FGFR1,STX17,SSR1,SDCBP,RPA2,CFTR,GRPEL1,STK38,ARFIP1,DLAT,PGK1,ITM2B,TEX264,RPL27,MAP4,RIT2,KARS1,SLC38A2,TMPO,STX6,LMAN1,RPS27L,FZR1,VTI1B,SLC39A10,RAP1B,CAMLG,RPL32,COMT,GTF2B,ACSL4,SH3GLB1,CRABP2,SURF4,TFRC,EXOC3,ARHGAP12,UBIAD1,ACTR1A,CENPM,FAM162A,RAP1A,MTCH2,SNAP29,RDH11,SLC6A8,AKAP12,DHX9,RPL3,SLC25A11,SLC38A1,PSMD14,H2AZ2,LAMTOR1,SNRPB,SLC1A3,BAG3,LDHB,HNRNPC,MYC,ACAP2,ATP6AP2,TCEAL1,FAM83B,PRMT5,DLST,EIF4B,TOM1L2,MTMR6,RPL27A,USP6NL,RANBP10,EMC1,AKAP1,RAB5A,HSPB1,AGR2,DDRGK1,PPFIBP1,RPL6,RAB5C,LANCL1,FHIP1B,UQCRH,VAMP7,SNRPD3,LYAR,RAB1B,STX5,RAB31,RPL18,CCR1,PTRH2,RAB4A,SOX2,H1-3,STBD1,PRPS1,RAB8B,RPL28,VAMP8,VDAC1,SLC20A2,NUP42,EFNB1,TRIM21,RABGGTB,RINT1,RBM3,TMEM87A,COL1A2,CDC73,EPHA2,TXNIP,ARFGAP3,SDF2L1,HMOX2,DEPDC1B,CTSD,SEC63,VIRMA,FERMT2,SNX3,YES1,RPL13A,LDHA,SCAMP2,VAMP3,RPLP0,HNRNPH3,SLC12A2,GOLGA5,JUP,DCTN4,AP1AR,LMNA,EIF3J,SNRPN,ARHGAP1,SEC22B,RABL3,TMEM209,PDHB,YKT6,MAVS,RTN4,ITGA2,MTDH,RPA3,OSBPL8,UPK1A,ESYT1,POR,NME2,RAB22A,TMEM199,MOV10,CAV1,DERL2,ALCAM,RPL35A,LDLR,CDCA3,EHBP1,SRPRA,ALDH1A3,H2AZ1,HRAS,RPL12,PTPN1,RPL15,SLC29A1,CCDC47,EIF3E,SMN1,MRPL22,CTNND1,OLA1,THRAP3,TF,FARSA,RNF115,SNAP23,DLG1,EHD4,STX8,RAB1A,FAM219A,CCDC25,SCFD1,MYO6,PRPF31,RAB11A,NIBAN2,VEZT,ERH,FZD4,RPL37A,EIF3K,ARF1,FAM91A1,FAM3C,ELOVL1,TBC1D17,VPS18,VAPB,RAB6A,DUSP22,EHD1,TOR1AIP2,NOTCH2,RAB37,WDR77,STX7,IL1B,PMAIP1,BET1L,RABAC1,EXD2,DUSP9,MED4,HAX1,PPM1B,CDK5RAP3,PIK3R1,ATG9A,WIF1,RAB11B,WDR44,SLMAP,AGK,SNX2,SNX1,CCAR2,SPTAN1,OCRL,KIF3B,SNX17,NEO1,TSG101,GJA1,WDR6,PLD3,STX12,GDI2,RAB6B,RPN1,STIM1,VAMP2,VPS33A,MACO1,RAF1,RETREG1,GOLGA7,SEMA4C,TNF,PRPSAP1,SCYL2,ZYX |
| 5.127e-12 | -26.00 | PPIE (peptidylprolyl isomerase E) | protein interactions | 10450 | 271 | 129 | 19454 | 5460 |
EIF4A3,GCFC2,PRKRA,MECP2,ELAVL2,BRAP,RBM22,RPL4,HSPA5,PHYHIP,PNO1,RPL27,CWF19L1,ELOF1,ZNF326,H2BC11,LMNA,TFIP11,RPLP0,WDR83,SF3A1,CPSF4,TOP1,FZR1,RPL35A,CDC5L,CWC15,SYNCRIP,SMAD3,RPL12,KIAA1143,LANCL2,RBM17,ERCC3,GTF2E1,HNRNPK,TRIM63,KPNA2,POLL,HUWE1,CDC40,TSSC4,CTNNBL1,SNRPG,RAB1A,SNIP1,DHX9,RPL3,IK,ILF2,PHF13,RPL15,ESS2,EEF1A1,SNRNP40,TUBB,MATR3,PRDX2,GNB1,SNRPB2,RPL10,RPS9,SNRPD2,PRMT5,YWHAZ,RIT1,RPS26,HSP90AA1,HNRNPC,SFN,MYC,SNRPB,PSMD1,SRSF2,TRA2B,FXR2,XRCC5,NKAPD1,SNRPA,SLU7,DDX5,CFDP1,HSPA8,CSNK1A1,SLC19A2,RPL27A,RALYL,BUD31,SNRPD3,SNRPA1,RPL7,SUMO2,HNRNPL,HSP90AB1,DHX15,RPL9,THOC2,RPL8,WDR82,MAGOH,YWHAB,RPL23,SLC25A21,ZCCHC10,RPL6,PRPF19,PDIA3,CTNNB1,YWHAG,HNRNPA1,KRAS,HNRNPF,SSRP1,RPL28,MCM6,SRSF4,RPS4X,HNRNPA2B1,PABPC1,HSPD1,SRSF7,BAG2,EWSR1,PCNA,SNRPE,RPL18,E2F4,MAX,RPS7 |
| 5.136e-12 | -25.99 | EMC9 (ER membrane protein complex subunit 9) | protein interactions | 51016 | 162 | 87 | 19454 | 5460 |
RPL22,RPL13A,EIF2S2,RPS12,RPS20,RPS3,PDCD4,EIF3G,ST13,RPL7A,MARS1,RPL4,RPL27,RARS1,RPLP0,ZNF326,EIF3J,ST7,TMPO,SPPL3,RPS16,RPL35A,RPL12,ALYREF,RPL32,RPS2,MAP4,RPL10A,RPL24,KARS1,EI24,EMC4,RPS13,RPL17,HNRNPK,RPL23A,RPL3,EMC2,DHX9,SRP72,RPL15,CCDC47,YTHDF2,RPSA,RPL10,RPL19,MATR3,RPL37A,RPS9,EIF3K,RPS5,RPL39,HNRNPC,EMC1,STAU1,DDX5,NUP50,DDX39B,XRCC5,RPS28,PLAA,OTULINL,RPL27A,RPL7,RPLP2,HP1BP3,RPLP1,RPL9,RPL8,RPL23,EMC6,PRPF19,PSMD3,RPL6,RPL28,RPS4X,RPS24,RPL31,PABPC1,MTA2,SNRPE,RPL18,RPS23,RPL29,DNAJC25,RPS7,EMC10 |
| 5.191e-12 | -25.98 | MAPK6 (mitogen-activated protein kinase 6) | protein interactions | 5597 | 463 | 198 | 19454 | 5460 |
METTL2A,HSP90B1,MAP3K12,HNRNPH3,HAUS2,ZNF671,PSMC4,UBA52,LPXN,EDF1,SLC7A1,ARMCX5,PRKCB,RTN4,SQSTM1,ARFGAP3,NDUFB10,ATP5F1A,MGAT1,UBE2L3,JUNB,STUB1,CYRIB,DTYMK,ALB,CFAP298,NDUFS3,ILF2,RAD23B,SERPINA1,SELENOK,CCT5,SOCS3,HUWE1,FARSA,TF,SLC25A10,GLUL,SFXN1,ECD,PSMD7,DNAJC7,CALR,TMBIM6,ATP5PD,ZNF7,MYBL2,VPS18,SLC25A3,PRKAB1,MAPKAPK5,CA12,IDH3B,CNTN1,RADX,RGS19,PSMC1,STX7,CCND3,PFDN6,KDSR,MTG2,CUL3,SLC41A3,MCM4,MCM3,DYNLL1,NDUFAF4,CDC7,NDUFS6,POLR2C,RNF126,AP2S1,RAF1,TPD52,HSDL2,FAF2,ASPM,PPP2R1A,PSMD12,TMED7,RPS27A,NAT9,NUDT5,HSPD1,SLC25A5,PLSCR1,BCKDK,NDUFA4,UBE3A,BAG2,HAX1,HNRNPD,CDH13,SLC20A1,ATG9A,CLPX,PSMD3,OCRL,SPTAN1,ATXN10,EGLN3,WDR6,PSMB4,HBB,CDC42,NTPCR,TOMM20,TEX264,ELOF1,ATP1B3,ATP1A1,RRP7A,RAB2A,PSMB2,CDO1,CFL1,GPX1,ADRM1,CDIPT,NECTIN2,CALML5,PSMC5,SGTA,PTPMT1,TMEM165,ARPC3,PSMC3,UBL4A,TP53,MTCH2,FAM162A,CSE1L,CYTH2,DDR1,ATP5PF,PSME1,SLC25A11,SLC16A1,TRAFD1,SHC1,AKAP8L,MAP4,MZB1,ZNF24,HP,VPS26C,MIF,RPS27L,ILVBL,DKC1,FUNDC2,TMPO,SSBP1,PPT1,PIH1D1,PSMB3,HNRNPA0,MYOZ3,HSPA8,CCT2,PSMD14,DNAJB6,SFN,PSMD1,MLF2,PSMD4,ATP5F1B,TCEAL1,PSMD6,POLR2B,RPL10,ATP6AP2,VDAC2,HDAC11,TUBA1A,PSMA2,VDAC1,CCT8,ACTR1B,HSPB1,MAPK4,XPO1,NOL4,CTNNB1,DDRGK1,HNRNPL,LSM5,TCP1,SUMO2,VAMP7,UQCRH,HSP90AB1,CCT7,RAB31,PSME2,POLR2L,MAGED2 |
| 5.241e-12 | -25.97 | TFCP2 (transcription factor CP2) | protein interactions | 7024 | 426 | 185 | 19454 | 5460 |
RPA2,SDCBP,AKR7A2,SPTBN1,SUMO1,MARS1,HSPA5,MRPL40,PGK1,PRDX6,RPL27,PML,OAT,BICD2,RPS17,CFL1,RPL7A,MORF4L1,PPP1R1B,GNAO1,RPS3,NUPR1,GNAI3,CDK8,TFCP2,PPP3R2,TP53,RPSA,PHF1,RPL17,CAPZA1,HNRNPK,DHX9,TCEA2,RPS2,RPL10A,AGPAT1,RPL24,H2AC4,ADPRH,POLR3GL,GAPDH,PGAM1,MYL12A,RPS16,MIF,EEF1B2,SYNCRIP,DNAJC27,GPC4,RPL27A,GNB4,FXR2,STAU1,EEF1G,PHB2,HSPA8,DDX5,RPS28,RPS26,CKB,CCT2,LAMTOR1,BTF3,HNRNPC,LDHB,PSMA4,PRMT6,ATP5F1B,RPS23,MOB3C,GNAZ,RPL18,TUBB4B,STMN2,TUBA1A,EEF2,RPS7,TOP3B,RPS4X,RUVBL1,MYO1B,GNA11,RPL31,CCT8,PABPC1,YWHAB,XPO1,LAMP2,RPL6,ZCCHC10,HSP90AB1,RPS10,TCP1,CORO1C,SIN3A,RPLP0,JUP,HSP90B1,CNP,RPS14,PIAS1,NF2,GTF2I,PDHB,EIF5B,RPL4,CDC73,IRAK1BP1,PPIG,ATP5F1A,ZCCHC12,TUFM,SLC25A31,GNAI2,LDHA,TMOD3,TXN,YES1,SLC25A4,ALB,UBE2I,CTNNA1,ENO1,TUBA1B,ILF2,EEF1A1,HINT3,MRPL11,RPS13,RIGI,POLL,CPNE2,RPL23A,RAB1A,FOXP1,GLO1,FOXC2,PRNP,RPL12,AIFM1,UBP1,ACTA2,MYL6,H2AC1,PRDX3,COIL,RP2,HADHA,GNA14,HSP90AA1,RPS5,LMNB1,MYO6,GNB1,IP6K1,PRDX2,TUBB,LAMTOR3,ACTB,FAM43A,HAPLN2,FOXP3,RPS9,GNG12,RAN,ENO2,RPN1,RAF1,FLOT1,RPS24,PLCB1,HSPD1,SLC25A5,HAX1,HNRNPD,RPL23,PPIA,WIF1,INA,RPL7,SPTAN1,WDR6,PHB1,NABP1 |
| 5.350e-12 | -25.95 | ATG10 (autophagy related 10) | protein interactions | 83734 | 213 | 107 | 19454 | 5460 |
GDI2,RPS23,EIF1AX,RPS11,TOP3B,BUD23,RPS7,MAK16,RBBP7,RPS4X,PPWD1,CCT8,RPS24,WDR12,VPS4A,RB1CC1,MED4,ATG9A,TAF7,UTP6,ATG7,XPO1,LSM5,TCP1,NOP58,RPS10,CCT7,POLR2L,ATP6V1A,MCOLN1,WDR82,VPS18,ADSS2,ACTL6A,ATP6V1C1,MED11,SRSF2,ATP6V1G1,RPP14,SAP18,NRBF2,LYSET,RPS28,TTC1,EMG1,FTSJ3,ATG3,CCT2,MED10,RCL1,POLR1B,VMP1,CUL3,NOP16,ATG101,LDB1,KANSL3,TAX1BP1,ACTB,DLST,FAU,SCN2B,RPS9,CCT5,IMP3,TBK1,CSE1L,NOC4L,HNRNPK,IMP4,NEDD8,PAK1IP1,VPS16,RPS13,RAB1A,MAP1B,BECN1,ATP6V1D,CLP1,RPS2,RPS16,PTPN1,GTF2B,PWP2,TSR2,LSM2,UTP15,MYLIP,RPS14,CCNH,RPL4,WDR3,LSM8,AATF,NLE1,PRPF4,BAP1,LSM6,RPL7A,MAT2A,RPF2,CFL1,PPAT,UBA3,RSL24D1,CSTF3,WDR45 |
| 5.350e-12 | -25.95 | ATP5PD (ATP synthase peripheral stalk subunit d) | protein interactions | 10476 | 213 | 107 | 19454 | 5460 |
CISD1,ATP5F1A,TUFM,NDUFB10,UQCRQ,VIRMA,SEC63,MGST3,PTPMT1,TSSK1B,HEXIM1,CYC1,MTRES1,PAK5,COX6C,P2RY12,STOM,GPR35,CDC42,CFTR,COQ8B,TOMM20,HSPA5,FBXW7,GFM1,SQSTM1,MAIP1,RETREG2,TSNAX,BRD3,P2RY1,TMEM70,DPP4,ATP5MG,COX5A,DSTN,COQ8A,AIFM1,SSBP1,COX4I1,GFM2,SLC25A24,NDUFS3,MAP1LC3B,AURKAIP1,TBK1,UBL4A,ATP5PB,MTCH2,MRPL11,FASTKD5,RAB1A,ATP5PF,ARHGAP19,FMC1,MTG2,AUH,PMPCA,TM9SF4,ATP5F1B,TAX1BP1,ACTB,B4GALT3,DKK3,TACO1,ACKR3,CCDC90B,CAV2,NDUFA5,VAPB,KLF3,ATP5PO,TOMM22,HSCB,RER1,PHB2,ATP5IF1,TACR1,HADHA,EXD2,FBXW4,MED4,MRPS26,STK4,PDIA3,PTPN5,STOML2,OPRL1,DNAJB9,ADCK1,CYB5A,GATD3,PHB1,FAM136A,NDUFA12,PTRH2,PDHA1,RAF1,TFG,CHCHD2,G3BP1,KRAS,VDAC1,ATP5F1D,HINT2,HSPD1,NDUFA4 |
| 5.394e-12 | -25.95 | RPL14 (ribosomal protein L14) | protein interactions | 9045 | 489 | 207 | 19454 | 5460 |
RPL6,WWP2,RIOX2,DDRGK1,AGR2,FOSL2,DRG1,RBM5,EED,RPS10,HSP90AB1,EEF2,RPS7,DNAJC25,ZNF526,RPS23,RPL18,MOB3C,PABPC1,RPL31,H1-6,KRAS,RPS4X,RPL28,MYC,BTF3,FTSJ3,CHTOP,NSA2,RPS26,BST2,ZCCHC7,MATR3,RPL10,APEX1,MTF1,RPL27A,MRPL12,PIH1D1,EIF4B,RPS28,EP300,STAU1,SSR3,UFL1,ENY2,COPS5,SNRNP70,RPL24,TUBG1,RPL10A,CDK12,NOL12,RPS2,RPL32,RPS27L,CAND1,RPS16,FZR1,SPPL3,SURF6,DKC1,RBM42,TP53,RPSA,UBL4A,IMP3,RBM34,DNAJC2,TFCP2,SNIP1,MAP1B,RPL3,IMP4,RPL17,MEPCE,RPL7A,RPF2,ZSCAN25,H2BC9,RPS17,RC3H2,SPOP,EIF3G,UBE2H,PSPC1,RPS3,RBMX2,RPL10L,SRPK2,RSL24D1,CFTR,RPA2,ZNF770,KLF4,HEXIM1,PML,NLE1,RPL27,BAP1,RNF113A,RPS15,HSPA5,MAP3K14,RPL23,RB1CC1,RSBN1L,PHB1,MYEF2,RPL8,FOLR1,RPL9,HP1BP3,RPLP1,RPLP2,RPL7,RAF1,B3GNT2,OTUD6B,MAK16,RPL29,CHMP4C,EZH2,RPS11,ARGLU1,SLC25A5,RPS24,TRIM37,G3BP1,RPS27A,CUL3,NOP16,CUL2,ZNF668,BRCA1,FYTTD1,RPS5,ZNF22,RPS9,SEC61B,RPL37A,RPL35,RPL7L1,RPF1,RPL19,MAD2L2,EMC9,APOBEC3C,NMRAL1,NOP53,GPC1,G3BP2,SPATS2L,GRSF1,HDAC6,MPHOSPH10,RCHY1,ACTA2,RPL12,SRP14,LDLR,PRNP,RPL35A,FBP1,RPL15,TAF1D,LLPH,SRP72,ILF2,NKRF,RPL23A,KLF10,VRK1,PAK1IP1,PTGES3,RPS13,PPP1CC,TUFM,FBXO7,RPL26,PPIG,METAP2,CCNF,PTEN,RPS20,RPS12,PRKRA,RPL13A,RPL22,TPT1,RPS14,GRM2,METTL14,RPLP0,RPL26L1,ZNF574,SIRT7,RPA3,MTDH,KIN,HMGB1,RPL4,FBXW7,NF2,NPM3,BRIX1,PIAS1 |
| 5.680e-12 | -25.89 | positive regulation of intracellular signal transduction | biological process | GO:1902533 | 1048 | 409 | 18204 | 5365 |
ADRA1A,SRC,ANGPT1,LAMTOR3,RB1CC1,IL18,PIK3CG,TRIM21,FASLG,LEP,PHB2,HEXIM1,SCHIP1,ICAM1,SERINC3,TAB2,NLGN1,DOK5,TCIM,BIRC5,GPR37,F7,PIK3CA,MIR15A,P2RY12,ROCK1,PDCD4,PRKRA,OSM,CUL3,SHOC2,RXFP2,OPRK1,NTRK3,NTRK2,FGF23,BMPR1A,NDC80,AKR1C2,TICAM1,LAMTOR2,MIR29A,ADGRG1,BMPR2,IL23A,SEMA7A,VEGFA,CD40,SYK,FGF16,CCAR2,TRIM5,RGL2,FBXW7,NKX3-1,ZDHHC17,RPS7,FCGR2B,S100A8,PRR5L,MIR24-1,DUSP22,ALKAL1,TRIM62,LACRT,BIRC2,TFRC,TRIM32,RAP1A,PIK3AP1,GADD45A,TRAF6,TLR2,TICAM2,NDP,MIR181D,LAMTOR1,TBK1,GRM2,DIRAS1,CCL19,NUP62,PML,JMJD8,NHERF1,NPSR1,NPPC,MAP2K6,CHI3L1,HCLS1,DRD1,PIH1D1,MIR16-1,AKT3,TRIM34,PRL,MIR186,GPR137,FLOT1,PELI1,GPR37L1,OR2AT4,TRAF7,GRM1,HAX1,ADRB1,NEUROD2,FGR,DDX1,UBE3A,IL12B,TMEM100,DNAJC27,PTP4A3,CD86,UBB,GADD45G,TRAF3IP2,BAX,ERP29,NDST1,IL6,MCL1,GLIPR2,PLCB1,TLR9,RTN4,HDAC3,TNIK,MIR21,VWF,MIR519D,CPNE1,NACC2,SEMA4C,CLEC6A,EDNRA,NMI,RRAGB,VAV2,DSTYK,GPR65,PMAIP1,UCN,LPAR2,CD36,MIOS,AKT1,TGFB3,IL1B,MIR182,UBE2V1,WNT7A,PPP3CA,RPL26,SMAD4,DRD3,AGR2,TLR6,TMED4,MIR675,CALR,BOK,EP300,LPAR6,IGF1,SPRED1,PDCD10,TMEM106A,MT3,GPX1,CTNNB1,GH1,TXN,EIF2AK2,GNAI2,KIT,ADRB3,AR,DIRAS2,CARTPT,UBE2N,SOD1,CRKL,ARRDC3,MIRLET7B,TGFBR2,IRAK1BP1,TTI2,FGF1,BST2,TIRAP,PLA2G5,NRP1,TFG,PPP3R2,JAK2,PPP5C,P2RY10,BAD,RAMP3,DVL2,CDK5RAP3,GLCE,PRKCE,GHR,ADORA1,FGF22,PTPN1,FGFR1,P2RY1,ACKR3,TMEM33,ITGAV,PRDX2,DDIT3,RPS15,TLR4,PTPN11,PIP4P1,SPPL3,TP53,SDCBP,RRAGA,TNFSF10,LPAR1,DDX5,CLEC7A,AVPI1,MAP3K3,SESN2,RELL2,GPNMB,IRAK4,ZNHIT1,TNFAIP8L3,KLHL22,TRIM52,F11R,CCDC22,CSNK1A1,F10,RPL23,IL34,IKBKB,RBCK1,GAPDH,TRIM44,SIAH1,HINT1,C1QTNF1,TPBG,S100B,EPO,EZH2,OSBPL8,CHRNA7,RPS20,HFE,MAPRE2,FGF7,HMGB1,CXXC5,MIR23A,PYCARD,HRAS,AGER,LURAP1,PLEKHF1,RAF1,CX3CL1,ROCK2,MUL1,MAP3K11,FGF3,TWSG1,FGF17,TNF,ADIPOQ,TRIM6,EDA2R,RPS3,PHB1,AVPR1B,SEC13,CX3CR1,TRAF2,MSX1,NLRP3,ACVR1,PRKCA,GJA1,DDR1,CSNK2B,TIFA,F2,SPHK2,ZNF622,RELL1,GPR89A,NPY5R,ILK,FBXW11,DDT,HTR2A,BCL10,TPD52L1,CCL3,MIF,OPRM1,STK3,MAP3K12,IRF3,AKAP12,TRIM68,TLR3,SOS2,DOK6,CCL5,GPR17,CDC42,PPIA,DUSP19,NUPR1,FERMT2,MYC,FLCN,IGF1R,MIR126,MYD88,GADD45B,ATP2C1,TRIM26,HBEGF,CD4,CD81,ARL6IP5,IGFBP3,GPBAR1,TAB1,MAVS,RC3H2,TMEM101,SLC20A1,DOK4,EEF1E1,CAV1,MEF2C,GPR35,STAMBPL1,PIM2,CD28,MYORG,DKK1,CA8,COL3A1,PDE8A,SOX2,PTPN22,PROX1,RNF167,HAND2,MTDH,ADRB2,GREM1,SEMA5A,CDH13,CCR7,MAP2K3,IL1A,TGFB2,KRAS,NOTCH2,ACTA2,SPRED2,TRIM8,NCK1,LTB,FGF10,CBL,NDFIP1,ANKRD6,SOX9,RHEB,HCST,TRIM22,PROK1,GHRL,CCL21,PICALM,LITAF,IFI35,BECN1,LTBR,FIS1,ACTN4,CAV2,RIT2,DHX15,SLC38A9,MAD2L1,FKBP1A,TLR7,RAP1B,IGFBP4,SHC1,CCR1,PRKCB,MAP2K1 |
| 5.758e-12 | -25.88 | RPA4 (replication protein A4) | protein interactions | 29935 | 452 | 194 | 19454 | 5460 |
CCAR2,SPTAN1,RPL7,CACYBP,RPL8,HNRNPA1,ZNF207,RBBP7,G3BP1,SSRP1,SLC25A5,HNRNPA2B1,RPS24,RPN1,SKA3,RPS11,JPT2,SNRPE,ARFGAP1,FEN1,RPL29,NUP153,RPL35,RBBP4,RPL19,PRRC2A,SNRPB2,RAN,PARP2,RPL37A,RPS9,SEC61B,BRCA1,PFDN2,EXOC8,JPT1,MCMBP,NSFL1C,UNC45A,TXNL1,NUP50,TTC1,PSMA3,ADNP,RPL35A,MAPRE2,RPL12,WDCP,ESYT1,CNN3,GLO1,THRAP3,RPS13,GALNT2,TCOF1,SFXN1,RPL23A,SERPINA1,YTHDF2,CCT5,EEF1A1,CD2BP2,RPL15,TMOD3,RPL13A,CEP97,SEC63,STUB1,CTTN,SENP5,RPS20,CHORDC1,CDC73,MAPRE1,RPL26,NONO,PFKFB2,RPL4,DAD1,CHMP2B,RPA3,DVL2,HMCES,SQSTM1,CDK1,TOX4,COX6C,CDR2,SF3A1,EEF1E1,RPS10,HNRNPL,TRIR,AASDHPPT,SNRPD3,PRCC,FUBP3,UBFD1,CDC23,DRG1,CNOT2,RPL6,PPIB,HNRNPF,RUVBL1,RPS4X,RPL28,GNA11,PABPC1,CCT8,RUVBL2,RPS23,CRKL,RPL18,SUPT5H,RANBP1,SERPINA3,TAGLN2,MATR3,PSMD4,CCT2,H2AZ2,RBM27,ZMPSTE24,HNRNPC,SNRPB,FXR2,HNRNPA0,EEF1G,STAU1,PTRHD1,SF3B1,AKAP1,DDX5,ADSS2,PAK2,NUFIP2,PIH1D1,RPL27A,ZC3H14,RPS16,TMPO,CDC5L,SSBP1,EEF1B2,SYNCRIP,COX4I1,RPL32,MTAP,SMCHD1,RPL24,TAF9,RPS2,RPL10A,MAP4,RBM17,HNRNPK,RPL17,NAE1,SLC25A11,SLC16A1,RPL3,DHX9,DDX42,CHAMP1,IK,CAPZA2,ARPC3,TAB2,TP53,IPO8,ADRM1,BCCIP,PSPC1,LIG3,SRP54,MACROH2A1,EIF3G,BICD2,IGF2BP1,RPL7A,TOMM20,HSPA5,RPL27,PGK1,PRDX6,RPA2,UTP15,UBE2M,SPTBN1,SUMO1,CD2AP,MND1,SETD3 |
| 5.842e-12 | -25.87 | regulation of locomotion | biological process | GO:0040012 | 1164 | 448 | 18204 | 5365 |
MSN,KIF2A,CRKL,MIR492,MIR497,MIR221,MIR130A,PLAA,MIRLET7B,STK26,TGFBR2,ARRDC3,KIT,GNAI2,MIR206,MIR320A,MET,LMO4,XBP1,MIR10B,SSX2IP,MIR448,PRKCE,NRP1,GNB3,CCL28,TIRAP,FGF1,BST2,JAK2,PTEN,ATP8A1,SEMA3C,ITGA2,MIR92B,STARD13,IL1B,AKT1,PPP3CA,WNT7A,FAM107A,LMNA,MIR182,CCL24,TCAF2,HYAL2,RBBP4,CALR,PIK3R3,PDCD10,SPRED1,SAP30,IGF1,MIR519D,CD9,FGFBP1,MIR21,ELP6,SEMA4C,GLIPR2,RGCC,CD99L2,EMP2,RTN4,PLCB1,NUS1,MIR129-1,MIR210,MIR204,SIN3A,PAX6,RIGI,TPPP2,VEGFC,DAPK3,EMC10,MIR449A,IQSEC1,TMEM196,OXSR1,MIR10A,BVES,MIR885,FUT1,AKT3,FAM89B,CD274,PLXNC1,AKT2,PADI2,MMP9,IL6,ABHD6,CHRM4,TP53INP1,MIR379,MMP14,MIR185,DUOXA2,LDB2,FGR,MIR223,ACVR1C,MACIR,GNRH1,FOXP1,STAT5A,CYRIB,TRIB1,CCL19,DPP4,MIR222,CYP1B1,RARRES2,CCDC25,GADD45A,MIR181D,PLP1,CCL4L1,MIR16-1,MIR491,TERT,DRD1,FUT9,SEMG2,CLXN,CCL2,NHERF1,STAP1,ADIPOR1,GFUS,CREB3,PRR5L,NOG,ELP3,HDAC6,FBXW7,CCL23,CD40,ACVR1B,TMIGD1,CCR4,MIR205,FGF16,DUSP1,SELENOK,MED23,TMIGD3,GLUL,CCN3,TRIM32,DUSP22,MIR101-1,MIR24-1,CERS2,SMAD3,VSIR,STC1,MIR493,FZD4,MIR551A,MIR218-1,NTRK3,SOX14,MIR296,FLRT2,CCL1,BRMS1,NR2E1,PIK3R1,CCAR1,TIMP1,MIR29A,NF2,VEGFA,SEMA7A,MTA2,IL23A,BMPR2,ADGRG1,MECP2,BMPR1A,FGF23,FBXO7,MIR137,NFE2L2,ABHD2,RNF41,MIR140,CD200,KRIT1,PIK3CG,MIR939,THY1,CBLL1,ZNF609,ANGPT1,DAG1,SRC,SST,MMP28,MIR143,MIR15A,MIR135B,TACR3,ROCK1,P2RY12,IFNG,BMERB1,ICAM1,CD47,TIAM1,F7,ARHGAP5,SNAI2,SOX9,CTNNA2,CTNNA1,TNR,CCL21,RGN,GHRL,MIR20A,PRCP,TWIST2,HDAC5,CCR1,SAP30L,ACTN4,CD151,MIR29C,USP14,MIR200C,ATP2B4,CHRM1,CD200R1,GREM1,CFAP20,ADTRP,CCL20,PROX1,TNFSF18,CCR7,CDH13,MIR152,SEMA5A,CCR6,WASL,COL3A1,RAP2B,SPINT2,NCK1,MIR9-1,ADAMTS1,TF,ATP5F1B,FGF10,DEFB1,TGFB2,DUSP3,MAP2K3,IL1A,ACTA2,DPEP1,MIR146A,CD81,HBEGF,PTN,IGFBP3,CLDN1,S100A11,UBE2I,MIR149,IL4,MIR31,TACR1,MIR342,MYD88,LDLRAD4,HSPA5,MIR208A,ING2,MSTN,MEF2C,MIR150,SWAP70,CAV1,CSF2,MIR132,DDT,SCG2,IL12A,ATP5F1A,MIF,CCL3,HSPB1,CDC42,SEMA6C,TMSB10,MIR126,IGF1R,SFRP1,CCL17,FERMT2,MIR3173,EPHA4,MIR200A,DEFB124,AKAP12,CCL5,GPSM3,CDH11,MIEN1,CSNK2B,AIF1,CCR2,FOXC2,ARF6,CLDN3,ACVR1,LDB1,CCL25,MIR214,PRKCA,GJA1,CHST2,CXCR3,MIR424,MIR338,CCL18,TMSB4X,TNFRSF14,CXCL10,RHOB,DUSP10,AGER,ZNF304,MIR361,PYCARD,PLG,MIR23A,HRAS,CXCR4,EMILIN1,TBC1D24,NTNG2,CDK5,PHACTR1,BCL6,CXCL12,EPHA2,CLDN4,MIR495,CORO1C,MAPRE2,FGF7,HMGB1,YTHDF1,ING1,RAB11A,PRKX,CX3CR1,MIR145,XCL1,MIR640,ROCK2,BRMS1L,TBCCD1,CX3CL1,MIR1298,RAF1,ADIPOQ,TNF,MIR505,FGF17,RBBP7,FGF3,DDRGK1,MIR30A,F10,PTGER4,MIR503,PPARG,MIR212,CXCL13,SP1,RHOJ,AAMP,GPNMB,JUP,MIR711,CDKN1B,MIR193A,STK24,RNF20,RAP2A,GAB1,OSBPL8,MIRLET7G,MKKS,IL34,MIR638,TPBG,AP1AR,LGALS3,MIR335,TLR4,MPP1,CDK6,MIR590,CCL8,ARHGEF39,KLF4,CCL11,ST3GAL4,RAP2C,FGF22,ADORA1,ADORA3,RAC2,ITGAV,ACKR3,FGFR1,VASH1,SOD2,MIR34A,MAP3K3,SYNJ2BP,MIR1-1,CLEC7A,GPR173,CYGB,TNFAIP6,ITGA6,MITF,RRAS2,ST6GAL1,MADCAM1,CLIC4,STK4,SVBP,CXCL8,MDM2,LPAR1,SDC4,MIR188,SDCBP,MIR133B |
| 5.845e-12 | -25.87 | AKAP1 (A-kinase anchoring protein 1) | protein interactions | 8165 | 498 | 210 | 19454 | 5460 |
PDCL,HSP90B1,LMNA,RBMS2,CNP,TIMMDC1,ARHGAP1,PSMC4,MRPL20,YKT6,MAVS,RPA3,XPOT,HMOX2,DEPDC1B,CDC16,SEC63,TECR,PRSS37,SLC25A4,MGST3,LDHA,RAB14,GANAB,OPTN,CCNF,STUB1,GPAM,MTARC2,YTHDF2,COMTD1,CCDC47,PRDX4,FASTKD5,FARSA,TF,HUWE1,SFXN1,SLC25A10,RAB1A,DNAJC7,MUL1,RAB23,MFN1,HM13,RAB22A,SLC25A46,MOV10,CALR,PLGRKT,CAV1,TSPYL4,SLC25A17,TOMM70,ARF6,TRAK2,CDCA3,ARL10,AIFM1,RPL12,PTPN1,SLC25A3,ARMCX3,LARP4B,RAB6A,MTX2,UNC45A,FBXL4,PXMP2,NT5C3A,ATAD1,YTHDF1,NUBP2,TTC1,EXD2,DNAJC3,HSDL1,DHRS1,BAX,TOMM40,CUL3,RAB11A,NDUFAF4,TNPO3,CHCHD3,CFAP91,SARM1,RMDN3,CYB5R3,ARF1,FAM177A1,CYB5B,GDI2,RAB6B,NME1,RPN1,FAF2,CYB5R1,RAF1,SAR1B,PSMD12,ETFA,ERP29,BAG2,SLC39A7,SCYL2,LRRC57,HAX1,RHOG,SIAH2,MARCHF5,PDIA3,PRKCQ,EGLN3,CACYBP,INA,CYB5A,PHB1,OCIAD2,SAMM50,STX17,RPA2,HSPA5,BNIP3L,TOMM20,SLC25A51,KDM1A,DERL1,RAB9A,RAB29,TMEM263,CALU,ATP1A1,DNAJC10,CISD1,ST13,GORASP2,PRKACB,RAB2A,RPP25,TAB2,SURF4,ZMYM4,MTCH2,RAP1A,SNAP29,KBTBD4,FKBP8,CAPZA1,TMEM33,RAB3B,SLC16A1,ABCE1,SLC25A11,NUS1,SMIM12,HP,FAR2,LMAN1,FUNDC2,RAC2,DSTN,ACSL4,STT3A,AIP,FUNDC1,TOMM22,ARMCX2,PHB2,EMC1,RAB5A,HSPA8,PYM1,SERPINH1,ZMPSTE24,FIS1,CCT2,CKB,ESR2,POLR2B,ATP5F1B,PHF21A,FAM83B,PTRH2,RAB4A,NUDT19,CSTF2T,NUDCD3,MIEF1,STBD1,RAB8B,RAB18,VDAC1,USP30,PABPC1,DRG1,CDC23,PEX3,FKBP4,YWHAH,PPIB,XPO1,RAB5C,PGS1,COX14,RAB1B,PEX13,FUBP3,RAB31,RAB35 |
| 5.877e-12 | -25.86 | RPS15 (ribosomal protein S15) | protein interactions | 6209 | 359 | 161 | 19454 | 5460 |
PIH1D1,FGF17,SYK,H1-5,PABPC5,RPL27A,G3BP2,NOP53,UFL1,HSPA8,RPS28,RIT1,H1-1,ICAM1,RPS26,RPS5,SP1,ATG3,PSKH1,RPS29,BTF3,RPL39,ZNF668,CUL3,MYC,RPL10,RPL19,ESR2,RPL35,MRPL23,SEC61B,RPS9,RPL37A,FAU,SART3,RPS23,RPL18,RPS11,PTRH2,CHMP4C,EZH2,RPS7,SOX2,OTUD6B,MAK16,H1-3,B3GNT2,FLOT1,RPS4X,SRSF4,RPL28,HMGN4,H1-6,KRAS,G3BP1,RPS24,SRSF7,RPL31,RPL23,DRG1,AHSA1,AGR2,DDRGK1,CPEB1,HNRNPA1,RPL6,WWP2,SERINC3,G2E3,RPL7,PAIP1,RPS10,RPLP1,RPLP2,PHB1,SRSF1,RPL8,RPL9,KLF4,RPLP0,HEXIM1,RPL26L1,ZNF574,FGF13,CFTR,COMMD3,CDC42,MPV17,RPS14,HSPA5,PIAS1,RPL4,FBXW7,HMGB1,NPM3,RNF113A,SQSTM1,SIRT7,BAP1,RPL27,UBE2H,RC3H2,EIF3G,PPP1CC,RPS17,RPL26,RPL7A,TNFAIP3,RPL22,SMURF1,RPL13A,RPL10L,PTEN,RPS20,RPS12,PRKRA,FGFBP1,SEC61A1,GSK3A,METAP2,PSPC1,RPS3,SRP72,DNAJC2,LLPH,RPL15,PLA2G12A,APOBEC3D,H2AX,RPSA,TP53,FBP1,RPL17,MEPCE,RPS13,VRK1,RPL3,RPL23A,ATP6V1D,RPS2,RPL24,SNRNP70,TUBG1,HDAC6,COPS5,CD81,NFKB1,MRPL24,SURF6,MDM2,TMPO,CDK9,RBM42,RPL35A,CAND1,RPS16,FZR1,PRR3,RPL32,RCHY1,KRR1 |
| 5.960e-12 | -25.85 | regulation of defense response | biological process | GO:0031347 | 843 | 339 | 18204 | 5365 |
FLOT1,RNF34,PPARA,PELI1,IL6ST,HSP90AA1,IRF3,USP15,CD274,FOXP3,IL12A,DDT,BCL10,HSPD1,LDLR,HTR2A,ELMOD2,LILRB1,MATR3,PSMA6,CCL3,GPR17,PYDC2,MMP9,MIR142,APOBEC3G,PTGES,NUPR1,TRAF3IP2,USP38,MIR126,RSAD2,IL6,IER3,UBE2K,FGR,POLR3B,TLR3,DUOXA2,IL12B,LRRC14,FOXP1,MACIR,MIR223,GPSM3,CCL5,NLRP9,MIR21,LPCAT3,CD81,FABP4,MIR146A,MIR149,LILRA2,APOBEC3F,SFN,MYD88,MGST2,MIR31,SH2D1A,ABHD12,IL4,TNFRSF1B,IFIH1,TLR9,IFNK,IL20RB,GFI1,SOCS5,RTN4,ZMPSTE24,MEF2C,CASP12,LYPLAL1,UCN,POLR3F,BAP1,OPTN,CD36,CD28,TAX1BP1,CMA1,TAB1,MAVS,MIR204,CLEC6A,SERPINB9,NMI,FURIN,LYAR,IFNB1,TRIM11,CPTP,CAV1,SOCS3,RIGI,SIN3A,TYROBP,CREBBP,SELENOS,HCFC2,NCR3,TLR6,CCR7,ISG15,KLK3,DHX9,NOP53,VAMP8,TRAFD1,AKT1,IL1B,PTPN22,KLK5,CCL24,GPX1,TNFAIP3,HYAL2,GSTP1,FCN2,CLPB,MIR144,KARS1,GRPR,EP300,NFKBIA,IGF1,KLRD1,BANF1,SOD1,CNR1,IFI35,BECN1,IL2,MIR221,PAK2,MIR206,EIF2AK2,FAM3A,CD14,NDFIP1,IL22,STAT2,TRIM22,GHRL,MIR20A,FCGR1A,MIR488,DEFB114,TRAF3IP3,OAS1,CCDC92,LACC1,LTA,PRKCE,ACP5,STAT1,NR1H2,PLA2G5,TIRAP,MIR708,MIR187,CD200R1,MIR200C,NLRP6,MCPH1,JAK2,IRF7,TLR7,PIK3CG,NECTIN2,SEC14L1,CD200,NONO,MIR140,TRIM21,LEP,SQSTM1,TLR4,TOMM70,PHB2,MICB,KLF4,HEXIM1,MIR590,PTPN11,FGL2,ADORA1,SRC,PTPN1,PSMB4,HSPA8,MIR26B,IL18,NEK7,MIR15A,LGR4,IL13,TNFAIP6,TRIM45,PDCD4,IL21,CLEC7A,IDO1,CTSC,IFNG,CD47,IL17F,BPIFB1,PTGER4,CSNK1A1,TLR8,UFL1,IFI16,SLC15A2,PPARG,AREL1,IRF1,TNFAIP8L2,TRIM3,PQBP1,YWHAZ,CCL1,OSM,IRAK4,UFD1,PIK3R1,ZNRF1,SETD4,ATAT1,SAMHD1,RNF115,DROSHA,IL23A,YTHDF2,MIR195,SEMA7A,MIRLET7G,IKBKB,MIR181C,TRIM44,TRIM15,CNOT7,PPM1B,TLR1,IL15,NFE2L2,TICAM1,PYCARD,MIR361,AGER,DUSP10,CD226,PSMA1,TRIM5,STAP1,NFKBIL1,EMILIN1,S100A8,FCGR2B,BCL6,OTULIN,HMGB1,SYK,CD1D,MIR205,MBL2,ABHD17A,NLRP1,FEM1A,VAMP7,TRIM62,TRIM6,LY96,SELENOK,BIRC2,PHB1,YES1,KLRC2,RHBDD3,TRIM32,CCN3,MIR920,MIR145,PIK3AP1,SMAD3,CX3CL1,IL10,MUL1,XCL1,CAMK2N1,NT5C2,SARM1,TNF,ADIPOQ,XRCC5,PLSCR1,MIR657,RNF26,TBK1,TMEM126A,MAPKAPK3,NINJ1,TIFA,IRF4,CCR2,VAMP3,TLR5,TRAF6,EIF4E2,NLRP3,TLR2,TLR10,MIR222,TICAM2,CLEC12B,MIR17,CGAS,NPY5R,NLRP2,ALOX5AP,RB1,ARG2,CASP4,RAG1,KCNJ8,SPATA2,MIR16-1,MIR141,NFKB1,MIR105-1,TMSB4X,PDE2A,IL2RA,TASL,VAMP2,MAP2K6,PSPC1,LSM14A |
| 6.070e-12 | -25.83 | SART3 (spliceosome associated factor 3, U4/U6 recycling protein) | protein interactions | 9733 | 285 | 134 | 19454 | 5460 |
CTBP1,USP39,PSMB3,SYK,COIL,SNRPA,NUP50,EP300,CFDP1,PSMA3,SF3B1,BRCA1,FTSJ3,RIT1,NSA2,ICAM1,ELAVL4,CUL3,CFAP20,GRB10,MYC,SNRPB,PRPF31,RPF1,RPL7L1,RPL19,ESR2,SNRPB2,APEX1,MAD2L1,MIRLET7D,RPL37A,SNRPD2,SART3,RPL18,MOB3C,RNF126,SNRPE,RBPJ,RAF1,GTF2E2,SOX2,KRAS,PDIA6,FAM168A,MIR221,MIR1-1,WWP2,RPL6,MIR143,IFI16,EIF3D,LSM5,SNRPD3,HP1BP3,RPLP2,LSM2,RPA2,ACACA,MIR7-1,HEXIM1,RPL26L1,ZNF574,SNRPN,TPT1,MIR34B,RBMS2,AGO1,FBXW7,RPL4,MIR7-3,RPS15,LSM8,BRIX1,SIRT7,PML,PRPF4,RPA3,BAP1,RPL27,RNF113A,PPIH,LSM6,TXNIP,CDKN2AIP,UBE2H,PPIG,ATP1A1,RPL7A,RPF2,AR,ZSCAN25,RPL13A,VIRMA,CTTN,POP7,CCNF,RPS3,FCF1,MIR200C,CD2BP2,KPNA2,HNRNPK,THRAP3,NOC4L,LSM4,PSMA5,RPL17,SNRPG,OLA1,MEPCE,MIRLET7C,PALM2AKAP2,RAB1A,DHX9,RPL3,ECD,MPHOSPH10,H2AC4,USP15,RPL10A,MIR34A,LSM3,NOL12,CMSS1,CSNK2A1,COPS5,CAND1,FZR1,CDK9,RPL32,RCHY1,ALYREF,LDLR |
| 6.191e-12 | -25.81 | PTPN1 (protein tyrosine phosphatase non-receptor type 1) | protein interactions | 5770 | 615 | 250 | 19454 | 5460 |
CDIPT,ATL1,SEC61A1,SRP54,PSMC5,STAT5A,LYPD6,SRC,AKT1,C9orf72,TMEM41A,ATP1A1,TEX264,DERL1,RAB9A,TOMM20,CDC42,PAAF1,CFTR,RPA2,WRAP53,SSR1,FGFR1,PRKCA,LEMD3,CD274,AIP,CAMLG,RAC2,ARL6IP5,DNAJC1,LMAN1,ILVBL,TMPO,DPP4,DHRS7,FAM20C,CCL5,CSNK2A1,COPS5,TSNAX,STX18,PSMA5,NUP107,RAB3B,SRPRB,HNRNPK,FKBP8,CAPZA1,SNAP29,PREB,MTCH2,CDK4,DUSP1,ARHGAP12,TMEM31,TFRC,CAPN2,NFKBIA,RRAS2,PSMD6,PSMB6,APLNR,NPPC,ESR2,ATP6AP2,TMEM38B,MYC,PSMA4,COX11,SPCS3,ATG3,FIS1,COP1,MCAT,TMEM179B,DNAJB6,ZMPSTE24,EP300,RAB5A,AKAP1,MIA2,UFL1,EMC1,GOSR1,PHB2,TOMM22,GOSR2,SEC62,RAB35,STX5,DYNC1I2,RHOH,GLRX,COX14,LAMP2,DDX50,RAB5C,CTNNB1,DDRGK1,AGR2,PEX3,HSPB1,CYP2C9,RINT1,CCT8,KRAS,USP30,STBD1,DNAJC25,NUP37,PTRH2,RAB4A,GHR,DCUN1D5,VAMP3,CCNF,ELOVL4,RPS20,MSN,ZNF622,MGST3,COPE,TECR,SEC63,SEC13,HMOX2,NAPA,CASC3,RPA3,SYVN1,CLK1,MTDH,RTN4,MAVS,PPIH,YKT6,PIAS1,TMEM209,RABL3,MREG,SEC22B,ARHGAP1,TIMMDC1,ST7,LMNA,CDK1,STOM,SLC12A2,TMX4,GHITM,PDCL,AIFM1,SRPRA,ARL10,EHBP1,HSD17B11,SEC23A,RPL35A,ARF6,DERL2,TNFSF18,TOMM70,CAV1,TMEM199,EMC4,SLC25A46,LAMP3,HM13,HDAC6,POR,ESYT1,BRD3,OSBPL8,STYK1,NSDHL,LPAR2,NTRK2,EMC2,IGF1R,ARF4,PRDX4,GALNT2,CCDC47,CCT5,LBR,SRP72,FAM169A,ARF1,SNRPD2,RMDN3,GPR89A,SEC61B,TSN,LAMTOR3,ACTB,JAK2,CHP1,NDUFAF4,TMCC1,VEZT,RAB11A,CUL2,TMEM183A,RNF40,GGH,LMNB1,NTRK3,SCFD1,ATP2C1,EXD2,HSCB,IL1B,MCMBP,PXMP2,STX7,MTX2,PGRMC1,TOR1AIP2,PPP1CB,RND2,OTULINL,VAPB,SLC25A3,PHB1,GJA1,SLMAP,DIRAS3,EGLN3,ERLIN1,WDR44,DHX15,WIF1,ATG9A,MARCHF5,CDK5RAP3,RHOG,CDH13,TMT1A,EMC8,FLOT1,GOLGA7,RETREG1,MARCKSL1,MACO1,FAF2,ERLIN2,STIM1,EZH2,RPN1 |
| 6.211e-12 | -25.80 | TXNL1 (thioredoxin like 1) | protein interactions | 9352 | 216 | 108 | 19454 | 5460 |
CTNNB1,RIOX2,PSMD3,HSPB1,RHOG,GSTO1,KRT8,ATP6V1A,EED,NUP35,DIRAS3,KIF2A,ISG15,E2F4,RHOBTB1,RND3,TUBB4B,PDIA6,RPS24,UBE3A,HINT2,RPL31,PSMD12,PSMA1,TRIM26,PSMD1,SFN,MYC,ACO2,COP1,PSMD14,MYO6,DCAF4,CCT2,PHF21A,USP5,SNRNP40,TENT5C,USP16,PSMD4,DET1,RND2,TOR1AIP2,MTX2,PIH1D1,HSPA8,DDX39B,DNAJC22,PSMC1,PXMP2,SLC25A46,DNAJC4,PSMD7,TMPO,LMAN1,PRNP,PGM1,URM1,ACTR1A,EEF1A1,DDX39A,CCT5,TP53,RAD23B,PSMC3,NUPR1,DHX9,RIGI,CSE1L,SEM1,AR,USP14,TIA1,CIAO1,PSMB2,UBE2H,XPOT,DNAJC10,TXNIP,RPS20,EIF2S2,GSK3A,PSMA6,CTNNA1,CCNF,DEK,SH3BP4,ADRM1,MAGOHB,NDUFAB1,CDC42,PSMC4,ATG16L1,TMOD1,GSTP1,HSP90B1,SAMM50,IDH2,RPA2,SQSTM1,PRDX6,TXNDC17,RHOU,RPA3,SOD1,SLC25A51,HMGB1,KDM1A |
| 6.572e-12 | -25.75 | EEF2 (eukaryotic translation elongation factor 2) | protein interactions | 1938 | 464 | 198 | 19454 | 5460 |
PRDX3,NOTCH2,CRY1,PSMA3,HADHA,HSP90AA1,RPS5,RIT1,BRCA1,TOMM40,GALE,CUL3,RPL19,TUBB,SEC61B,RAN,EZH2,NME1,CHMP4C,PPP2R1A,LGR4,ERLIN2,RAF1,B3GNT2,SAR1B,TNF,EMC8,CDK20,TRIM37,RPS24,HSPD1,HNRNPA2B1,HNRNPD,RPL23,HNRNPA1,SRSF10,PPIA,NDUFS8,EGLN3,CACYBP,RPL7,ATP6V1A,FOLR1,PHB1,RARS1,JUP,METTL14,UQCRC1,CDK7,ATG16L1,FBXO9,PDHB,HMGB1,FBXW7,RPL4,ARPC2,SQSTM1,RPA3,SOD1,DVL2,EPHA2,CDC73,RUNX1,TUFM,HMOX2,AR,VIRMA,NDN,COPE,TXN,PTEN,ENO1,PPME1,CASK,NDUFS3,EEF1A1,MAP1LC3B,GGCT,FBP1,FBXO25,RIGI,SEM1,HUWE1,FARSA,EMC2,IGF1R,HSD17B10,RAB1A,FAF1,FBXO34,POR,HDAC6,CALR,ISYNA1,EMC4,MDM2,PRNP,RPL12,ARL10,EIF4B,PIH1D1,CNDP2,ADSS2,PAK2,PPT1,NEK7,NUP62,UFL1,HNRNPA0,PHB2,ADRB2,HSPA8,YAF2,EP300,DDX5,CKB,CCT2,BTF3,MYC,CREBBP,TAGLN2,ATP5F1B,DLST,RPS23,RPL18,PDHA1,SOX2,ISG15,EEF2,RPS7,RPS4X,HNRNPDL,KRAS,VDAC1,RPL31,PABPC1,POU5F1,HSPB1,AGR2,XPO1,CTNNB1,DDRGK1,IFI16,GSTM3,WWP2,RPL6,UQCRH,HSP90AB1,HNRNPL,SUMO2,HEXIM1,UBE2M,HECTD1,CYC1,RPA2,NEK2,CFTR,CAPN1,PGK1,RNF113A,BAP1,PML,MAPKAPK3,NBN,ATP1A1,UBE2H,SPOP,ATP1B3,RC3H2,RSPH1,MAT2A,RPL7A,SMURF1,DAPK1,KCTD9,EIF4H,RPL10L,UQCRC2,RNF8,TFCP2,DISC1,UBL4A,RRM1,TP53,MEPCE,CSE1L,MAP1B,RPS2,USP15,RPL10A,SHC1,CSNK2A1,COPS5,GAPDH,RPS16,CAND1,FZR1,EEF2KMT |
| 6.651e-12 | -25.74 | EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma) | protein interactions | 1968 | 288 | 135 | 19454 | 5460 |
NUPR1,FURIN,RNF8,SRP72,ILF2,TP53,RPL17,EIF3E,ARF4,RPS13,MAP1B,DHX9,RPL3,RPL23A,ABCE1,RPL24,SNRNP70,RPL10A,RPS2,DNAJC7,ENY2,HDAC6,EIF2B5,EIF2B2,RPS27L,CAND1,RPS16,FZR1,RBM42,CDK9,RPL32,CD274,AIP,ARL4D,EIF2B3,RPA2,RPLP0,RPL26L1,RARS1,EEF1E1,RPS14,CFTR,RPL4,FBXW7,NF2,EIF4E,RPA3,BAP1,RPL27,MTDH,SQSTM1,TRIM23,EIF3G,UBE2H,CDC73,RPL7A,SUB1,RPS17,RPL13A,NDN,RPL22,METAP2,CCNF,RPS3,PSPC1,RPS20,RPS12,SRP54,EIF2S2,RAB4A,EZH2,RPS23,PLD3,GTPBP1,RPL18,POLR2C,TENT5D,RPS11,E2F4,RPS7,KRAS,RAD21,RPS4X,RPL28,PABPC1,RPL31,RPS24,AGR2,DRG1,RPL6,VPS26A,IFI16,EIF3D,DDRGK1,XPO1,CCAR2,RPL7,EIF2S1,PHB1,RPL8,RPL9,RPLP1,RPLP2,NUFIP2,RPL27A,STAU1,UFL1,EIF1B,G3BP2,RPS28,XRCC5,PYM1,AKAP1,H1-10,PSMD14,LAMTOR1,POLR1B,RIT1,RPS26,RPS5,CUL3,CDC123,MYC,CASP4,RPS29,RPL39,BTF3,RPL35,PRRC2A,ESR2,RPL19,RPL10,EIF3K,ANAPC2,RPS9 |
| 6.916e-12 | -25.70 | regulation of metabolic process | biological process | GO:0019222 | 7052 | 2282 | 18204 | 5365 |
CXCL10,TNFRSF14,PSMD10,ZNF622,CIDEB,JPH4,SPHK2,FBXW11,RAG1,H2AX,SPINDOC,OGG1,TRIM23,MIR424,DDR1,TFDP2,DIS3L,MTRES1,PSME1,LDB1,STK38L,XAF1,EXOC8,MIRLET7C,CGGBP1,MIR1277,ACOT8,MIR581,RHOH,MIR657,HSPB8,PSMD14,LBH,FGF17,ADIPOQ,ROCK2,YAF2,MIR567,H2AZ1,TRAF2,CBX5,NMBR,TRIM6,EEF2,RPS3,FOXP4,H1-1,ETF1,CXXC5,YTHDF1,CORO1C,MIR495,EPHA2,INO80C,ZNF770,CAB39,S100A10,LARP4B,PLEKHF1,BATF,MIR23A,ZNF304,MIR361,AGER,SLC6A4,POLR2L,LSM6,RAD21,CLN8,CNOT7,MYRF,TGFB1I1,MIR934,GAPDH,FBXO22,ESR2,FZD6,CHRNB2,IER2,EZH1,RFXAP,IL7,MIR1262,ITK,DCP2,BTG2,ZBTB6,TSPO,RNF20,RAP2A,RNF187,MIR711,JUP,GPNMB,SP1,MIDEAS,CYP7A1,RPL23,SFRP4,RAB39B,PTGER4,MIR626,CSNK1A1,CCNA2,DIPK2A,TAF7,PFDN1,SPPL3,TENT5D,IDO1,IL21,CLEC7A,MIR216A,MITF,VPS72,KCTD20,ZNF451,ZNF671,IL13,TMEM14B,MIR609,MIR34A,FHIT,PTPRQ,HELT,VASH1,FGFR1,ATXN1L,SCAMP5,VGLL2,MIR155HG,ACSS2,PIWIL4,PTPN11,HDAC11,HUWE1,OPA3,CKS1B,ENC1,TRIM27,FOXI3,GHITM,TFPT,CDK6,NONO,MAD2L1,MMD,USP14,ATP2B4,PFDN2,MIR708,RIT2,MACROH2A1,SHC1,PRKCB,CTBP1,ZNF174,PAGR1,ZC3H14,TRAF3IP3,ZNF250,CIRBP,PRCP,TADA3,NFE2,MIR20A,CCL21,HBP1,BAZ1B,ATP1B1,CSTB,CISD1,MAFG,CDK7,SLC6A3,ACTA2,HNRNPH2,DBNDD1,RASL11A,CRIP1,RBM7,SRPK2,SVIP,NOTCH2,MIR144,PAK6,METAP1,CRYBA1,TGFB2,CHP1,SEC22B,RING1,PCNA,MIR612,MXD1,SPRED2,ZBTB38,PDE8A,NFKBIB,PTPN22,SOX2,USP13,RAP2B,IRF2,TRIM37,HSBP1,PXYLP1,FMO1,ABHD14B,PIWIL2,CDH13,TPPP,CCNQ,SNX33,GREM1,MIR940,ADTRP,MTDH,TRIM11,PFDN6,ATP6V1A,SP4,ACHE,RC3H2,USP8,HTR1A,SMG5,TAX1BP1,CD28,CBFB,HSP90AB1,ERLIN1,FKBP1B,VGLL4,CAV3,MSTN,ZCCHC17,MEF2C,BEND5,GFI1,RUNX1,ZMPSTE24,CNKSR3,ZMYM2,PKIG,MIR208A,IFIH1,COPS4,IFT57,WWP1,TAF2,SNX3,S100A11,ZGLP1,RPS27L,ARB2A,LILRB4,EGR2,PPP1R2,ARL6IP5,TRIM26,AP2A1,ZBTB42,HBEGF,DNAJC30,G3BP1,ATP6V0B,SPON1,DNAJC19,FMO2,HNRNPA1,MIR216B,WWP2,GLO1,THOC2,CREB1,FRMD8,IER3,APOBEC3G,PRDX3,TDRD7,IFNAR1,MIR556,MIR190B,CD83,PSRC1,SASH3,SAP30BP,KLF9,MOV10,APLN,GATAD1,INPP5K,HTR2A,TGIF2,HSP90AA1,SOCS4,SMAD5,MAGED2,KDM4B,H2AC13,WDR45,CDK5R1,PSPC1,CHI3L1,FOS,IRF2BPL,PRSS37,HINT2,RPAP2,SLC25A44,FAM168A,HNRNPF,LRIF1,ZKSCAN1,NFKB1,WBP1L,ARG2,TESK1,HLF,P3H1,LIPT2,MIR937,SUPT3H,PLP1,MIR802,MIR1180,MIR181D,NUDT12,MIR222,HP1BP3,TICAM2,TRAF6,POU3F4,CCNF,HOXD12,CCL19,RNF40,TMEM59,PLAGL1,MIR378A,TRIB1,ATG16L1,SCML2,SLC7A11,ELF5,DUSP22,CSRNP1,SMAD3,MIR24-1,ISCU,EIF4A3,KMT5B,TAF9,RHBDD3,CCN3,WNT2,HNRNPD,SELENOK,TMIGD3,IRF2BP1,TRIM62,SETD5,MIR205,PCGF3,KLF10,RALB,MIR924,MIR599,ELP3,FCGR2B,ZNF32,ATF3,STAP1,MIR653,AKR1C1,TICAM1,SMAD9,MECP2,MIRLET7I,MIR181C,BMPR2,MIR542,LYPLA1,MOG,CELF6,EXOSC3,BNIP3L,MIR29A,TAL2,EDC3,INSM2,UTP15,AFAP1L2,IRF1,ITM2B,PQBP1,LMO3,DDAH2,CCT5,MIR551A,TFIP11,NTRK2,STARD4,IFI16,METTL14,ACTR2,NBN,TCEAL7,CTNNBIP1,RGP1,GPR37,STX5,DTL,ZBTB5,BIRC5,TENT2,IFNG,TAB2,MEF2A,OAZ3,PRKRA,TOM1,LGR4,USP30,TACR3,MIR135B,MTMR2,NRDE2,SRGN,PTGES3,ANGPT1,ZNF609,PPID,SUMO2,SRC,ADRA1A,MIR34C,CDK20,HEXIM1,HNRNPK,ZNF22,ATF4,NOVA1,TRIM21,MAF1,BCL2L1,TIRAP,TSPAN15,PKIB,BST2,MIR573,PPP1R8,GSK3A,KPNA6,RAMP3,DEDD,DERL1,BAD,G0S2,ODAM,SNX12,ADRB3,AATF,H2AC4,MIR643,MLLT11,MIR206,PLAA,SKP1,CDK12,ARRDC3,PHF21A,CTDSP1,CRKL,MSN,TRIM24,DIRAS2,RFC3,EP300,BOK,OVOL1,WDR77,PIK3R3,CTSK,BACH1,CRTAP,GPX1,CCNI,ANXA7,TMEM106A,LSM14B,UBE2V2,CDC7,GMNN,ZNF862,ZMYND11,LMNA,MIR136,AKAP17A,H2AC6,MIR92B,MIR99A,PRMT5,GABARAP,SELENOS,TANK,GRB10,AMELX,DRD3,MIR9-3,KHDC1,SIN3A,LYAR,ELK1,RRAGB,EIF4E3,BCL2A1,MIR593,POLR3F,MIR210,POU5F1,H3C1,MIR197,ZNF592,RMND1,RMI2,MIR33B,ZNF280B,ILDR1,POGK,MIR548C,RTN4,ABCC2,FMC1,MIR651,TIA1,RGCC,EXOC1,MYBL2,MSX2,LILRA2,MIR375,HADH,MIR519D,RBFOX3,INHA,MIR30B,MTG2,STOML2,MIR190A,FOXP1,UBE3A,IL12B,RNF14,PCBP4,POLR3B,MIR185,DUOXA2,RSAD2,SERPINA1,MIR1-2,COPS7A,USP2,UBB,CAMLG,ZFP64,MIR107,BGLAP,PPP1R17,MORC2,JUN,PNP,MIR885,CBX3,VDAC1,ROPN1B,HSPD1,MIR449A,GNMT,MTA3,CXXC1,SERPINA5,EMX2,FLOT1,ZFP1,MED4,TOP1,LSM14A,TENT5C,SUPT5H,MIR16-2,MDFI,CDKN1A,MIR105-1,ZNF655,TAFAZZIN,ILK,TMEM107,RNF152,EID2,RPL6,NLRP2,MIR301A,TNFAIP1,ZNF365,H2AB1,MIR214,YWHAB,MIR502,ZBED4,PPM1D,ZHX3,NLRP3,IRF4,FUT8,H1-5,CLDN3,CASC3,MIR552,PDCD1LG2,CAMK2N1,MUL1,ANKRA2,NGRN,CX3CL1,MIR1298,ATP6V0E1,MIR624,FCGR2A,ING1,PHB1,RPA2,MID1IP1,DNAJC10,STUB1,FGF7,CDK5,HEXIM2,CLDN4,MIR615,PLAC8,RNF5,MIR649,KDM2A,MIR98,MIR628,DUSP10,GTF2A2,CCT8,PKIA,KPNA2,WDR6,MIR335,ZNF692,LGALS3,DET1,TRIM15,ZBTB14,ZNF189,CYP27B1,ZNF326,FAF1,PIWIL1,ZNF526,MIR195,HEXB,DROSHA,MIR1249,MIR198,TRIM52,CDKN1B,TRA2A,FOXJ3,HOMER3,MIR218-2,MIR193B,RBM3,SCFD1,UFL1,RBM15B,PSME2,MIR188,MDM2,HENMT1,SDCBP,MIR583,TP53,MIR1-1,DDX5,NCBP2,ZNF473,TIMP4,ZNHIT3,HSPA8,PPIB,CSRNP3,BAG2,INTS10,PTPN1,MIR147A,PAX9,DLG4,CER1,IFI6,ZNF790,JADE1,EIF4EBP2,FKBP1A,CD200R1,ING5,PELO,PRPF19,TRIM29,NR1I2,PPTC7,MIR339,CDC5L,IRF8,CCR1,SAP30L,MIR558,NUCKS1,HNRNPA0,CSNK2A1,CPEB1,GHRL,AZIN1,DHRS7B,PAEP,HOXC4,SART3,NDFIP1,CBL,SOX9,RHEB,S1PR4,BAG3,ZNF7,SNAI2,MIR489,RBM23,DLG3,DCAF5,PLD3,PARM1,DPEP1,LRP3,MIR192,KLHL15,ZFAND2A,DUSP3,MAP2K3,RERE,PAOX,SESN3,SCAND1,LSM2,MIR9-1,RPRD1B,OTUD7B,ZNF596,CHRAC1,RFC2,GLRX2,MIR367,HOXB1,SPOCK1,MIR600,DKK1,RAB1B,CCR7,STAT6,RNF8,DDX4,ADRB2,SRSF7,LCORL,C9orf72,MBD3,HAND2,PRDM4,CPTP,CHID1,MIR101-2,GPBP1L1,SPIN3,TADA1,SWAP70,MIR452,DKK3,RUVBL2,USP5,EFNA5,ING2,LANCL2,MIR150,MDC1,THAP1,MIR662,ILF2,MIR504,IL4,FAM98A,NKRF,DGCR8,MIR146A,SCML1,DMTF1,CCL5,CST3,RORB,MIR3173,AKAP12,DYRK2,TLR3,TRIM68,RPS14,MIR302B,FLCN,ZNF652,MIR484,MIR761,DUSP19,AGO1,CRYAB,NUPR1,SECISBP2L,FZR1,HNF1B,MIF,EIF5A2,RWDD3,IL12A,MIR132,BCL10,IRF3,MAP3K12,HEY2,ZNF518B,MIR1225,KLF12,PARD6A,STK3,RNF34,SETD7,CLEC9A,CCL2,CHCHD2,PHF23,SEMG2,PSMC5,DUSP6,IGF2BP1,NPPC,CIART,PDE2A,POU1F1,DNAJC1,EIF5B,RBM42,ARL2BP,JMJD8,SERTAD3,APOBEC3A,C1D,ZNF287,TACO1,MIR373,MYLIP,H2AC1,RARRES2,G6PD,DIRAS1,PIAS1,VAMP3,MIR32,MIR632,ZBTB39,ACOT13,FEZ1,CDK4,XRCC5,CYRIB,TBK1,VSIR,MIR363,APBB3,DCUN1D5,CERS2,MIR101-1,ZSCAN25,MED9,MAGEA4,UBE2L3,GPAM,TRMT112,TRIM32,RASD1,CNOT6L,PSMC4,SERTAD1,LAMP3,MED23,NLRP1,FGF16,SYK,PITHD1,HILPDA,BOLL,HNRNPL,EWSR1,TESC,S100A8,NOG,EAF2,PRR5L,FBXW7,PRDX6,MIR129-2,SELENOT,TRIM5,MALSU1,APOBEC3C,NSMCE3,ALPL,PPM1B,FGF23,EIF3E,PRELID1,NUDT16,MTPN,VEGFA,CTSA,MTA2,IL23A,CLK1,ZNF704,SATB1,TIMP1,PIK3R2,KLF1,MIR944,CCL1,YWHAZ,OSM,PRKACB,BSCL2,MIR301B,CAPN2,FZD4,KRBOX4,DEK,SOX14,CAMK1,BEX3,CD47,PIK3CA,IL17F,TAF10,TAF1D,NOSIP,ELOVL3,NTF4,TCIM,APEX1,ZC4H2,SUPT4H1,ROCK1,MIR15A,PHAX,CCDC85B,CSH1,KLF3,RB1CC1,SERPINI1,H1-3,ASB11,CD58,CD40LG,RNF41,MIR939,THY1,PDE4B,TFEB,MIR140,TAF11,PHC1,TCEAL1,GNB3,NRP1,PCSK9,MIR187,ACP5,MIR125A,FGF1,MIR450B,PSMA3,PRKCE,PARL,DIO2,ATF1,MIR10B,SMU1,RGMA,PFDN4,TERC,MED13L,XBP1,RPL13A,PID1,MIRLET7B,IL2,MIR130A,TRIM63,CYTL1,PAK2,PAIP2,TSC22D3,CCND1,HIRA,CAAP1,MIR492,CNR1,AR,SOD1,SPRED1,PPP1R11,BRD9,CLK4,NFKBIA,SAP30,SIRT7,TCF23,SNX18,MIR331,VDR,BAK1,MIR877,MIR345,OXTR,ZNF688,TEF,WNT7A,VSTM2A,CEBPE,MIR374A,SIAH2,TGFB3,AIFM1,FUBP3,RPS4X,ACO1,DUSP26,ITGA2,SERTAD2,CCT7,RPL26,PAX6,RIGI,GFPT1,SMYD3,TXNIP,WNT10B,MIR577,BABAM1,HP,OPTN,MIR454,PRKAG1,MIR887,TP53INP2,HDAC3,SMARCD3,IFNK,ATG7,MIR383,ZBTB16,MIR148A,ZNF24,DNAJB6,SFN,LCP2,EHD4,AQP11,NACC2,MIR648,ZNF507,TNIK,UBE2S,MIR96,ZNF513,MAGEC2,GNRH1,MACIR,MMP14,UBE2K,MCM6,ID4,AHCYL1,EIF4E,ZBTB2,ZNF581,TP53INP1,GADD45G,PADI2,CHMP1A,PTP4A3,BAHD1,ACTL6A,PPP1R12A,PPP2CB,MIR1224,DRAM1,CD274,FOXP3,AKT3,LMNB1,E2F4,CLIP3,PAFAH1B2,SNTA1,SPRY1,HAX1,KLHL25,SMARCE1,TENT4A,DCUN1D1,ZNF593,INPPL1,APOBEC3B,USP16,RFC4,HSP90B1,ELOVL6,SH3GLB1,TRA2B,ZBTB45,NFE2L1,BHLHA9,STRADB,CTTN,ADNP,DAP,CGAS,BRD3,PRKCA,RAD23B,ACVR1,EIF4E2,H1-6,AZIN2,F2,CCR2,POMT2,PIP4K2C,CAPN1,SLC35B4,BCL7C,PLSCR1,RBBP7,MIR505,NAA15,POLDIP3,CRLF3,MAP3K11,DDRGK1,MIR636,PTGFR,STN1,FERD3L,MIR640,IL10,MIR611,RAF1,ARMCX3,SRSF2,ZSCAN5A,MIR145,CX3CR1,DBH,MSX1,NKX6-2,RFC5,CDKN2C,TAGLN3,TRAF1,LY96,PPP1R1B,DFFA,HMGB1,BCL7B,RGS2,LBX1,SSBP4,VPS28,GABPA,GTPBP1,CXCR4,BCCIP,HNRNPH3,MIR875,HRAS,PYCARD,ZNF664,EPO,MNAT1,MIR28,SERPINA3,NR4A2,AP1AR,MKKS,IL34,IKBKB,CHCHD4,MIR422A,EGR1,MIRLET7G,NFYB,NCSTN,EIF4H,YTHDF2,UPF3B,IL3,EZH2,MIR554,CHRNA7,F11R,MIR193A,COP1,UFD1,GABARAPL2,HECTD1,ZNHIT1,FAXDC2,PGR,MIR106A,SESN2,PRKCQ,SLA2,PPARG,EMX1,DESI1,MIR30A,PAQR3,CCDC22,RRAGA,LPAR1,CXCL8,MIR133B,CCNY,FKBP8,CTSC,SVBP,LCMT1,MIR770,ITGA6,CYGB,UBE2D3,ATG101,UBP1,PSENEN,RAC2,PRDX2,TSHR,NKAP,SRSF1,P2RY1,MIR340,ADORA3,ADORA1,SIX5,FGF22,MIR590,TOMM70,SMG9,DDIT3,EYA3,MIR586,POLE3,DNAJC2,NLRP6,IRF7,SMAD1,MIR425,CCT2,MIR200C,XPO5,ZBTB26,ACTN4,ZSCAN1,MIR1260B,ORC5,FOSL2,LTA,SETD3,TWIST2,IDH1,OAS1,DIRAS3,RNF126,HNRNPC,SUMO1,CDCA7L,COPS5,TRIM22,MIR656,AIP,MTF1,CSTA,HSPE1,LITAF,PICALM,PYM1,DPY30,KRAS,IL1A,PPP1R3C,FGF10,NCK1,IL2RG,IRF6,CPT2,TF,WASL,TM4SF20,GCLC,DYRK1A,ATP6V1G1,MIR152,DDIT4,KLK3,ZNF177,ZBTB18,MIR147B,TNFSF18,CREBBP,PROX1,JCHAIN,IFNB1,CAV1,RBBP8,SOCS3,MEPCE,PPP1CB,MEAF6,MTG1,TAB1,TNKS,RBFOX2,RAB1A,NDUFA4,AGAP2,CDKN2D,ODC1,PIM2,SUPT7L,ZNF397,IRF9,CYP2D6,RBM22,SERPINB6,BUD31,MIR31,ALKBH5,BRCA1,SLC38A3,SMAD2,MIR342,IDE,MIR324,ZNF687,ZHX1,SNRNP70,UBE2I,APOBEC3F,PSEN1,TNKS2,MTM1,CD4,FITM2,GPSM3,ITM2A,MIR106B,CASK,SSBP2,PHF13,HCRT,DLX1,LRRC14,MIR553,MIR126,MIR184,ZER1,MYC,MIR142,MARS1,HSPB1,MIR490,CDC20,DAPK1,APOBEC3D,PDCD5,MIR105-2,MIR194-1,RPS6KA4,OSR2,CDK1,SNIP1,ATP6AP2,SSBP1,DDT,NFIL3,EED,MED21,MIR557,CHRM5,CTDSP2,TNFSF8,DISC1,HCLS1,TFCP2,BMPR1B,PML,CRADD,TERT,SNAI3,MIR491,MIR141,EIF2S1,PABPC1,GSKIP,CD2AP,CD38,LAMTOR1,NEK2,ZBTB25,FKTN,NDP,GADD45A,FXR2,CAMK2N2,H2AZ2,TLR5,SFTPD,MAGEB10,NR2F6,PCBD1,CRTC2,MIR920,RAP1A,PNRC1,SERPINB1,TUSC2,TFRC,ELOC,CLU,MIR23B,MINAR1,MED30,OTULIN,MACROH2A2,RPS7,PKNOX1,NFKBIL1,NKX3-1,ADIPOR1,STK38,NFE2L2,DNAJB4,FBXO7,SOX3,PRMT6,COX17,MPV17L2,SMARCB1,IVNS1ABP,BMPR1A,TFE3,SEMA7A,MIR549A,DRAP1,SRSF4,UBASH3B,MIR100,MIR625,GTF2IRD1,TRIM3,BRMS1,CCDC3,MIR618,MIR563,TLR8,CIPC,MYT1L,MIR296,ZNF319,NTRK3,EIF2B5,EIF4EBP3,MIR153-1,RFXANK,EIF3K,DYNLL1,MIR873,MIR34B,PLCL1,MED17,MIR7-3,HOXB8,STK16,FAM162A,TNFSF12,MIR765,SERPINH1,ZNF740,PIWIL3,SMARCA5,EIF1B,SH3BP4,SLC25A23,TCOF1,ZNF175,PHB2,MIR148B,LEP,SQSTM1,COMMD6,POLR2G,MCM3,CD200,MIR601,LMO2,PTEN,MCPH1,JAK2,FBXL19,MIR500A,MED31,MORF4L1,LRP6,STAT1,CAND1,USP3,CRY1,LACC1,DVL2,RAB27A,ABCE1,SMCHD1,CD34,DEFB114,LMO4,GRIA1,RIOK2,MIR377,CREBZF,TNFSF13,RLN2,GNAI2,CD14,EIF2AK2,PSMC3,MIR155,MIR221,ATP5IF1,SS18,NCOA5,MIR497,RRN3,CARTPT,SLC8A1,UBE2N,MAGOH,PDCD10,DR1,SNX5,MIR384,KARS1,PACSIN3,NAA16,EIF3D,HYAL2,SHLD1,MIR1227,SLC1A1,SP2,CTNNB1,CYFIP2,GPT,TSNAX,KLK5,H2AC7,COPS7B,MIR578,EID2B,MIR1271,UBE2V1,MIR938,TNFSF15,NOP53,SERPIND1,VPS26A,RNF128,LSM4,SMAD4,INO80E,IFI27,MED29,PC,SERPINB9,CD36,MIR129-1,RBBP9,PMAIP1,BAP1,DXO,TCF21,IREB2,FOXD3,SRSF10,LIG3,SMURF1,MIR330,EMP2,DNM2,NOS1AP,MOB3C,CREBL2,RHOBTB3,TSPAN17,UBE2B,SYNCRIP,NGDN,ANAPC2,WDR82,ELP6,CPNE1,DHRS4,RPS2,CKS2,COX7A1,ECD,MIR21,NPBWR1,YWHAG,THRAP3,FGR,LDB2,RNASEL,MIR633,CSK,RFX5,ABHD6,GTF2F1,ERP29,ZNF267,BTG1,HAS3,TRIM34,PRL,JUNB,OTX2,MIR186,DMAP1,LDLR,AURKAIP1,ENO1,ADRB1,NEUROD2,ZNF263,EEF1A1,PPP4C,MIR10A,VEGFC,TRAF7,IFNGR1,RXRG,PPARA,PELI1,RIOX2,NFYA,SDR16C5,RBM5,NDN,DRGX,CDK9,TMSB4X,TMEM39A,NAB1,MIR338,PHF12,SLC25A5,RNF141,RB1,CITED1,TYMS,MIR17,GJA1,MIR764,CEBPG,PAIP2B,CNTN1,RBM38,FOXC2,AIF1,TBC1D16,NEUROG2,CTSD,MIR9-2,SHMT1,TNF,HMGA1,ACTB,FGF3,TWSG1,RBPJ,SF3B1,NAB2,XCL1,BRMS1L,MIR191,ATP1A1,AVPR1B,SLC25A4,CDK8,EDA2R,PDE12,RUVBL1,HMG20A,DDAH1,SSU72,ORMDL3,TOP2B,BCKDK,PFDN5,CTDSPL2,HFE,SH3BGRL,BCL6,MIR1296,FBP1,OAZ2,ABHD5,HINFP,ITGB8,MED11,TBC1D24,ELAVL2,EMILIN1,PSMD3,IL1RAP,MZB1,ZNF511,TCF19,LURAP1,HINT1,C1QTNF1,HMCES,LUM,ZNF668,MIR638,RNF139,TRIM44,APOC2,RBCK1,B2M,IFRD2,RPS26,PSMB9,GTF2I,TCEA2,PRIM2,EIF2B2,LHX2,IMPACT,KLHL22,NQO1,HELLS,PLGRKT,RHOG,CHMP5,SUFU,MLF2,SUV39H1,MLF1,MIR212,MIR503,EPCAM,SGTA,APOBEC3H,MIR671,TNFSF10,ACTL6B,MAEL,CIAO1,GNAI3,STK4,MAP3K3,SOST,EPOP,ASCC1,ZC3H7A,OAZ1,PCGF6,MCM4,ZNF362,NEK7,SOD2,LEPR,MIR26B,SAP18,ZNF574,PCGF2,CRABP2,TRIP4,MGMT,UGT1A1,MIR99B,CNOT8,ITGAV,RAP2C,GHR,CIAO3,IP6K1,TGIF2LX,TMEM14A,ZBED3,KLF4,APLNR,TLR4,ARF4,TSN,BUD23,MIR29C,ZBED1,TLR7,IL5,EDF1,RGMB,KDM1A,HGS,PRMT2,PPP1CC,MIR511,MAP2K1,HDAC5,TOB2,STPG4,MIR936,ANKRD49,IGFBP4,FCGR1A,MIR488,EXOSC4,SUB1,MIR551B,RGN,IL1R2,STAT2,MIR429,TMEM168,HBB,DICER1,FIS1,ZCCHC7,BECN1,TOPORS,DLG1,MIR215,CNOT6,SF3B5,IGBP1,IKZF5,BANF1,DNAJB9,MIR346,MIR449B,MIR597,OSBP,MIR370,RLIM,NEDD8,RAB29,LTB,TRIM8,FBLN5,TLE1,MIR30D,MIR517B,MSL2,ATP6V1C1,BTBD10,FAM20C,MIR25,SPP1,RABL3,DHX9,THAP7,ISG15,UAP1,ZNF345,HCFC2,BHLHE40,ZNF501,MIR1226,MIR661,TYROBP,EEF1E1,FASTKD5,MIR876,KANSL3,FURIN,MAVS,MIR760,ZBTB17,H1-10,RPS9,TOX4,HSPA5,SOCS5,IL20RB,SPOP,HTRA2,OPHN1,BEND6,SERPINB10,TAF5L,NPTN,MYD88,ZNF436,IGFBP3,MIR149,CD46,CD81,TULP3,ARPP19,NLRP9,ZNF322,EFNA3,PELP1,MIR7-2,MIR942,ZNF821,DEFB124,MOSPD1,MIR200A,EPHA4,MIR605,SFRP1,MAGEH1,IGF1R,RTRAF,CSNK1E,FERMT2,TIMP3,RBM12,RCHY1,LRRTM3,CDC42,PPIA,CCL3,ID1,YWHAH,LILRB1,TPD52L1,BARX2,ATP6V1D,IL6ST,GTF2F2,RFX4,STOX2,ETFBKMT,CSF2,BTN2A2,SRSF12,MIR7-1,H2AC25,MRTO4,NHERF1,MAP2K6,WBP2,NUP62,ZNF805,MAPKAPK5,PIH1D1,DRD1,MIR16-1,RDH10,DCUN1D3,ZNF575,HNRNPDL,CCNH,MRPL13,GTDC1,MRPL12,CYP1B1,GCHFR,MIR183,RPS13,TLR2,FAM161A,RNF10,AKAP8L,PTHLH,HCAR1,VRTN,PPIF,VIP,STAT5A,RNF26,SPTBN1,CD2,NIF3L1,ATRAID,WEE2,TCEA1,XPO1,TNRC6C,LACRT,STAR,EGLN3,BIRC2,DUSP1,YES1,HR,ASB1,PRKAB1,NPC2,NR1I3,CH25H,PSMC1,CD40,TMBIM6,ACVR1B,MED10,HDAC6,SGF29,MIR208B,INTS12,NME2,MIR616,POLDIP2,MAGEB1,FOXA3,CCAR2,MIR592,MED22,ALKBH4,CREB3,STK11,IL15,MIR769,MIR137,TLR1,BCL9,MIR532,FABP5,MIR194-2,MIR298,MIR455,MIR652,SLC38A2,MIR874,CCAR1,NF2,CEP85,ATP6V1E2,SETD4,CUL3,NR0B1,MIR24-2,RAN,PIK3R1,NR2E1,MAGED4B,FOXP2,MIR30E,PSMD1,MIR922,ISX,NIBAN2,ELK4,H2AJ,MIR218-1,TCP1,MIR493,TRUB1,CCNB1,CRYM,SPOPL,IFT52,CBX7,STAU1,NEO1,SERPINB11,PDCD4,MIR139,CACUL1,MAGOHB,MIR143,ETV6,CAMP,IL18,GTF2H2,MIR572,MIR891B,BZW2,UQCC2,WRAP53,ELK3,EID1,FASLG,INSIG2,PIK3CG,HNRNPA2B1,TSG101,E4F1,NR1H2,EGLN2,ZNF343,CDK5RAP3,MIR448,MET,MIR1251,TOLLIP,EIF4A2,MIR320A,MIR631,TSPAN5,ANP32B,KIT,FAS,TGFBR2,MSH6,PHF1,HNRNPAB,UBE2D1,UCP2,CNOT2,WTAP,ENY2,PTRH2,DKC1,ROMO1,APH1A,HMX2,MIR604,IGF1,MIR639,SKIC8,ATP6V1G2,CALR,NSG1,MIR675,GRSF1,MAX,GSTP1,TXN,RBBP4,TNFAIP3,GH1,CCND3,TOX,NEUROD6,INPP5E,MXI1,MT3,CREB3L4,FAM107A,PPP3CA,CLP1,MIR182,ELAVL4,SLC45A3,ZNF787,IL1B,MIR569,DYRK1B,AKT1,AGR2,TLR6,EXOSC8,IFNA13,SLCO3A1,MTERF2,RADX,EIF4B,MIR211,MIR595,IKZF2,SSBP3,MAD2L2,FOXS1,NMI,DSTYK,ZNF576,MIR423,CLEC6A,MIR204,ZBTB33,TAPBP,CD80,ANXA4,LPAR2,UCN,GABPB1,GTF2A1,MED27,MIRLET7D,MIR196B,ADM2,MLLT6,TNFRSF1B,KCNIP3,ORMDL1,TLR9,PLCB1,RPL10,MIR580,METTL18,MCL1,PPP2R5A,E2F6,SMG8,CDKN3,PPP1R10,DNAJC3,FABP4,CDC73,MEF2B,IFNA2,LPCAT3,DNAJB2,G3BP2,ACVR1C,MIR223,NKX3-2,KPNA1,ERLIN2,FCER1G,DDX1,TBC1D25,ELF1,TOM1L1,AGPAT1,MOB3B,EFCAB7,IL6,MIR379,TRAF3IP2,BAX,USP38,ADIPOR2,SOX21,PAIP1,IFNA10,LSM5,GNAQ,CD86,PYDC2,MMP9,COPS2,VPS26B,AKT2,PSMA6,ERRFI1,MATR3,HMX1,FOXN2,MPV17,UHMK1,MIR589,CARHSP1,SF3B4,MIR130B,PRNP,BVES,DAPK3,MIR607,GPR137,SLX1A |
| 6.965e-12 | -25.69 | modification-dependent protein catabolic process | biological process | GO:0019941 | 494 | 216 | 18204 | 5365 |
CHMP4C,AREL1,CSNK1A1,FBXO44,ZNRF1,RNF20,UFD1,KLHL22,HECTD1,CUL3,KLF1,COP1,PSMD1,TRIM3,RNF187,RNF148,CHMP5,PSMB9,FAF1,FBXO22,RNF115,CCAR1,SPSB3,PCYOX1L,RNF139,CUL2,NFE2L2,FBXO7,UBE2H,RBCK1,SIAH1,HUWE1,CRBN,ANKIB1,FBXL7,DDIT3,SQSTM1,TRIP4,CHMP1B,PSMB4,TRIM45,CACUL1,FBXL14,VPS4A,ADRM1,ZFAND2B,ANAPC16,UBE2D3,CDC26,FBXL3,DTL,RNF146,MDM2,SPOPL,PSMB5,CDC23,RNF10,PSMD14,RNF26,RNF133,RNF40,FBXO3,RNF144B,MYLIP,CCNF,NAE1,RAD23B,FBXW11,TNFAIP1,UBXN2B,FBXW4,DISC1,PSMC5,PML,RMND5B,FBXW7,HECW1,RNF5,HDAC6,PSMD3,PSMA1,PSMC1,PSMD4,STUB1,FEM1A,BFAR,SH3BGRL,VPS28,UBL4A,NSFL1C,ANAPC13,TRIM32,UBE2L3,FBXO31,PSMA2,ELOC,KBTBD6,BIRC2,PSMC4,UBAP1,APPBP2,GID4,KCTD10,UBE2I,ANAPC2,TRIM26,UBE2S,PSMB2,ECRG4,MTM1,KLHL3,PSMB10,SPOP,ZMPSTE24,SMURF1,WWP1,PSMB11,MAEA,UBE2B,RHOBTB3,BAP1,RNF7,CHMP2B,TP53INP2,ANAPC15,KCTD17,CHMP2A,PSMB6,IFI27,RC3H2,RNF34,PELI1,KLHL25,FBXO8,UBE2A,PSMA6,HECTD3,PPP2CB,RNF122,HERC3,FBXO11,USP38,RCHY1,ANAPC4,TOM1L1,FZR1,FAF2,CDC20,PSMB7,UBB,CHMP1A,UBE2K,CDC16,RNF14,UBE3A,WWP2,TOPORS,PSMC3,SKP1,PSMB1,PLAA,UBE2N,UBE2D1,XBP1,TOLLIP,SPSB1,PSMB3,CBL,NDFIP1,PSMD7,SYVN1,PSMA3,GSK3A,HGS,DERL1,RNF126,FBXL19,EDEM1,TSG101,USP14,ANAPC11,OS9,RNF128,VPS4B,RPS27A,RNF8,ISG15,UBA52,RNF167,UBE2G2,HERC4,AKT1,FEM1B,SIAH2,CTNNB1,TNFAIP3,RNF11,GID8,FBXL4,OTUD7B,UBE2W,DCAF11,UCHL3,FEM1C,PPP1R11,PSMD12,PSMA5,RLIM,ZFAND2A,FBXO9,NEDD8,WDR77,PSMA4,KLHL15,ARMC8,PSMD6 |
| 7.004e-12 | -25.68 | HNRNPC (heterogeneous nuclear ribonucleoprotein C) | protein interactions | 3183 | 595 | 243 | 19454 | 5460 |
H2AC13,MRPL40,RBM22,KDM1A,BANF1,BAP1,RNF113A,TWNK,CWF19L1,ZNF326,SDCBP,RPA2,TFIP11,HEXIM1,SUMO1,CFTR,AGO1,SRC,SRPK2,ZNF330,PSPC1,PHAX,RC3H2,SPOP,RRP7A,UBE2H,ELAVL2,IGF2BP1,CEP85,PTPN11,SMARCA5,KPNA2,NEDD8,CDC40,MEPCE,SNIP1,DHX9,RBM41,DISC1,TFCP2,NUPR1,TP53,STRBP,UBL4A,H2AX,ZNF581,ESS2,FZR1,CAND1,CDC5L,TMPO,DKC1,ILVBL,SYNCRIP,MRPS9,CHCHD1,SHC1,H2AC4,SNRNP70,MAP4,USP15,KPNA1,ENY2,DPP4,CSNK2A1,COPS5,SSR3,STAU1,TRA2B,FXR2,HNRNPA0,UFL1,SAP18,XRCC5,NGRN,SNRPA,DDX39B,SLU7,DDX5,EP300,RAB5A,GPHN,SF3B1,HSPA8,CSNK1A1,PIH1D1,NCOA5,NUFIP2,ZC3H14,PABPC5,MTF1,TOMM22,LMO3,RALYL,SNRNP40,MATR3,APEX1,DLG4,CMTR1,VDAC2,PHKB,SMU1,SF3B4,FBXW11,HNRNPC,HNRNPAB,EPS8,MYC,APOBEC3B,LMO2,SNRPB,CCDC85B,BTF3,HMGN4,NUP42,KRAS,PAX6,HNRNPDL,PABPC1,RPL31,TUBB4B,RHOBTB1,SMARCB1,MTA2,SUPT5H,RANBP1,MSX2,SOX2,SNRPA1,HNRNPL,PAIP1,SRSF1,EED,AGR2,FOSL2,MAGOH,MGMT,WWP2,RPL6,DDRGK1,CTNNB1,XPO1,HMGB1,FBXW7,AATF,PIAS1,MBD3,RPA3,INPPL1,METTL14,LMNA,SF3A1,BRINP1,CDK7,RBMS2,YES1,VIRMA,SH3BGRL,TUBA1B,EIF4A3,EIF2AK2,CCNF,TRIM24,UBE2I,PRKRA,IVNS1ABP,CASC3,PPP1CC,THRAP3,VRK1,CTNNBL1,RIGI,MDC1,CLEC7A,NKRF,PPP1R12A,ZC3H11A,SEPTIN7,ILF2,OR5A2,GPAM,APOBEC3D,PRNP,TOP1,CWC15,CDK9,LMBRD1,PRR3,CRBN,FGR,SSX2IP,MOV10,APOBEC3F,NKAPD1,PSMA3,LARP4B,EMC9,USP39,VAPB,ACTL6A,ACTB,RBBP4,MRPL23,SNRPB2,MYO6,BRCA1,FYTTD1,FAS,RIT1,MAGEH1,NLRP3,CUL2,CUL3,TOMM40,SMARCE1,TRIM37,GNL1,AHCYL1,SSRP1,SRSF4,AP1M1,UBE2A,HNRNPA2B1,SRSF8,SRSF7,CHMP4C,EZH2,TPBG,RAF1,JUN,PSD2,BUD31,SNX1,SPTAN1,PPIA,PHB1,FOLR1,SASH3,SYT4,CAMSAP2,HNRNPD,TRA2A,HNRNPA1 |
| 7.066e-12 | -25.68 | PRMT5 (protein arginine methyltransferase 5) | protein interactions | 10419 | 450 | 193 | 19454 | 5460 |
PHF1,H3C1,KPNA2,ACTR1A,UBL4A,CDK4,TP53,INSIG2,RAD1,CDK8,ALYREF,EPHB6,MXI1,FZR1,TPM3,USP15,RPL10A,H2AC4,SHC1,SNRNP70,RNF113A,RBM23,BAP1,NBN,HSPA5,BCL6,WDR3,KDM1A,ING5,CAPN1,UBE2M,HEXIM1,ACACA,LDHAL6B,RPA2,ZNF326,PSMC5,ING2,SMURF1,DYRK1A,TRIM54,CACNB2,ADRM1,PDCD4,CALU,UBE2H,LSM6,RC3H2,TRIM21,EWSR1,PDIA6,RBM3,PABPC1,PSMA1,KRAS,RUVBL1,TUBA1A,TOP3B,SUPT5H,ARFGEF1,SMARCB1,MTA2,WDR82,SIN3A,ZNF436,EIF2S1,SNRPD3,YWHAG,DDRGK1,GAS8,IFI16,DCAF4L2,WWP2,MAGOH,YWHAB,AGR2,HDAC5,HSPA8,RAB5A,EP300,SLU7,UFL1,ELK4,DIO3,DUSP14,MTF1,PIH1D1,PRMT5,GTF2F1,CMTR1,ZNHIT6,POLR2B,APEX1,ESR2,MATR3,PSMD6,PSMD1,SNRPB,COPS7A,PRMT6,GTPBP2,CIRBP,PSMD14,CHTOP,FBXO25,VTA1,OLA1,SNRPG,SMN1,LSM4,CTNNBL1,RPL15,FBP1,MRPL11,TRIM6,EFNA3,HRAS,EMC4,CLK1,RPA3,PHYHIP,SIRT7,PRPF4,SMC4,ST7,CDK7,RBFOX2,ATG16L1,SNRPN,CCND1,SH3GLB2,DCTN4,METTL14,LSM2,GANAB,STUB1,CCNF,EIF4A3,EZH1,VIRMA,RUNX1,NTAQ1,NONO,ZMYND19,HOXC4,TDP1,JAK1,FAM76B,UBE3A,TRIP4,ARGLU1,MCM6,IRAK4,COPS4,G3BP1,RBBP7,ACTN4,PPP2R1A,CSNK1E,RPS11,POLR2C,SNRPE,EZH2,GJA1,MYEF2,PHB1,EGLN3,LRWD1,CCAR2,HNRNPA1,MAP3K14,PSMD3,UCK1,AHSA1,RPL23,CRY1,ZDHHC17,G3BP2,NSFL1C,ALKBH3,WDR77,ACTL6A,SNRPD1,SNRPD2,JAK2,RBBP4,SMARCE1,ACO2,CUL3,HSP90AA1,RIT1,YWHAZ,BRCA1 |
| 7.111e-12 | -25.67 | HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5) | protein interactions | 51191 | 240 | 117 | 19454 | 5460 |
RPL7,RPS10,PPP2CB,FBXO32,FBXO31,CBL,PEDS1,UBE2D1,CTNNB1,MAP3K14,DDRGK1,ATG7,XPO1,MARCHF5,UBE2E2,IFI16,IMPA2,UBE2A,UBE3A,FBXO3,RPL18,ISG15,NUP153,RANBP1,TXNRD1,RPL10,RPL19,ESR2,HECW1,ACTB,ANAPC2,UBE2S,RAN,NLRP3,COP1,UFD1,CUL3,NOP16,CUL2,MYC,CREBBP,TMED5,CCND3,SKP1,POLA2,UFL1,UBE2D3,HSPA8,CTBP1,CDKN1A,H1-5,SURF6,KMT5B,MDM2,CGAS,SPPL3,NLRP1,PRR3,UBE2N,UBE2G2,SRP14,RPL10A,DNAJC7,RPS2,BECN1,SMAD4,NME2,MUL1,GAPDH,NEDD8,ANAPC11,HUWE1,HSD17B10,RPL3,RPL23A,NAE1,HBP1,UBE2B,RPL15,TP53,FBP1,VIRMA,UBA3,UBE2L3,SMURF1,RPL13A,CTSB,UBE2I,PRKRA,FGFBP1,CCNF,STUB1,UBE2H,UBE2E3,RC3H2,RNF148,CCNB1,PIAS1,RPL4,FBXW7,STK38,UBE2K,DGCR8,B2M,MTDH,SYVN1,IRF3,SIRT7,UGDH,RPLP0,UBE2M,WWP1,FGF13,RBMS2,CCNA2,CCND1,UBE2W |
| 7.277e-12 | -25.65 | EIF4B (eukaryotic translation initiation factor 4B) | protein interactions | 1975 | 357 | 160 | 19454 | 5460 |
EIF4E,HSPA5,AATF,GTF2I,SQSTM1,TNFAIP1,RNF113A,RHOU,BAP1,RPA3,PHACTR1,PML,PRKCA,UBE2M,RPA2,METTL14,EIF3J,CDK7,MAEL,ATG16L1,RPS14,SNRPN,SMURF1,DYRK1A,RPL22,VIRMA,SRPK2,RTRAF,PHAX,RPS12,RPS20,ALB,CREB1,PSPC1,RPS3,CCNF,EIF4A3,METAP2,CTNNA1,NAPA,MAPRE1,KCNJ2,UBE2H,EIF3G,NIF3L1,TXNIP,BICD2,RC3H2,CFL1,RPS17,ATP5F1A,RPS13,CAPZA1,EIF3E,NUP107,TTC4,HNRNPK,TOLLIP,RPL23A,PSME1,CAPZA2,DDX39A,UBR7,KBTBD4,FBP1,TBK1,CCT5,TP53,TRIM6,RBM42,MRPS23,FZR1,RPS16,PRNP,SEC23A,SMAD3,TSNAX,RPL24,CSNK2A1,HDAC6,RANBP10,G3BP2,UFL1,GPC1,STAU1,MCMBP,HSPA8,DDX5,RAB5A,XRCC5,EIF4B,NCOA5,PAK2,SSH3,EIF4A2,TSN,DYNLL1,FBXO22,SNRPD1,RPS9,CMTR1,EIF3K,RPS5,RPS26,CCT2,FBXW11,PSMD14,YWHAZ,RNF40,SAMHD1,MYC,SFN,CUL3,RPS4X,HNRNPDL,KRAS,G3BP1,LASP1,SLC45A3,RUVBL2,RPS24,RTCB,HSPD1,RPL31,HNRNPA2B1,PABPC1,CCT8,RPS11,DOHH,RPL18,RPS23,PLS3,CHMP4C,RPL29,NUP153,OTUD6B,RPS7,EEF2,TXNRD1,CCT7,FAM98A,RPS10,SNRPD3,OSBP,SNX1,GJA1,TSG101,RPL9,AHSA1,HNRNPD,DDX1,MAGOH,YWHAB,HSPB1,HNRNPA1,XPO1,YWHAG,YWHAH,EIF3D,IFI16 |
| 7.569e-12 | -25.61 | EMC2 (ER membrane protein complex subunit 2) | protein interactions | 9694 | 402 | 176 | 19454 | 5460 |
EPHX1,HSP90B1,GHITM,LMNA,ST7,CDK7,UQCRC1,SEC22B,SF3A1,PCK2,HMGB1,PDHB,SPCS2,RTN4,SYVN1,RPA3,MME,HELLS,RHOU,SH3BP5L,DNAJC8,HMOX2,TUFM,ATP5F1A,CSGALNACT2,RALB,SEC63,GANAB,ENO1,CIB2,NDUFS3,PGM1,CD2BP2,CCDC47,GALNT2,PSEN1,DNAJC30,TSSC4,EMC2,SFXN1,NSDHL,ESYT1,NME2,POR,SLC2A1,EMC4,SLC25A46,CALR,MRPL24,DBT,EXTL2,DERL2,PTPN1,HACD3,FKBP10,EMC9,OTULINL,RND2,PGRMC1,WDR77,DNAJC22,PYGB,HSCB,HADHA,EMG1,DNAJC3,ATP2C1,RIT1,RHOB,TMED4,MED17,TUBB,SPCS1,SEC61B,RMDN3,CYB5B,GDI2,NME1,RPN1,FAF2,EMC10,EMC8,HNRNPA2B1,HAX1,RB1CC1,RHOG,EMC6,MARCHF5,STOML2,HMGA1,TMEM237,NDUFS8,NOP58,PHB1,CYC1,USE1,RPA2,CFTR,CDC42,HSPA5,LPAR1,MRPL40,TNFAIP1,DERL1,PGK1,DDX46,UBE2H,ATP1A1,SUB1,NOPCHAP1,PSMC5,LIG3,UQCRC2,SLC25A24,TFRC,APOO,ZNF581,MTCH2,ATP5PB,RRM1,FKBP8,L1CAM,MAP4,POLB,GAPDH,PPIL4,RBM17,KARS1,LMAN1,DNAJC1,TMED9,RAC2,RAP1B,COX4I1,MRPS9,UBAC2,EDEM3,GOSR2,SERPINB6,PHB2,NDUFS2,EMC1,SF3B1,PYM1,ZMPSTE24,MDH1,FIS1,ZMAT3,PSMD1,HNRNPAB,OST4,ESR2,ATP5F1B,VDAC2,S1PR4,LMBR1L,RND3,PDHA1,TUBB4B,EEF2,DNAJC25,SUPT5H,CCAR1,CHCHD2,ABCF1,NDUFB8,NDUFV2,UQCRH,TRIR,RHOH,PAIP1,RAB1B,CORO1C,GYS1,RBM5,SRSF1 |
| 7.787e-12 | -25.58 | SDHA (succinate dehydrogenase complex flavoprotein subunit A) | protein interactions | 6389 | 374 | 166 | 19454 | 5460 |
EIF2S1,KCTD10,NDUFS8,PPIA,EGLN3,RMND1,CCT7,PHB1,SDHAF2,GATD3,RHOG,BPNT2,DDX1,HSPB1,YWHAB,PDIA3,PIK3R1,PPIB,NDUFV2,YWHAG,HNRNPA1,NAB1,CHCHD2,KRAS,MCM6,FLOT1,SSRP1,IMMP2L,HSPD1,SLC25A5,CCT8,SDHC,HINT2,RUVBL2,PDIA6,COX8A,RPN1,NDUFS6,PDHA1,TMEM14B,TOP3B,RAF1,PPP2R1A,EEF2,LRRC8A,CHCHD3,PARL,ESR2,FCHSD2,APEX1,LMBR1L,CCDC90B,CYB5R3,POLR3B,CCT2,CKB,LMNB1,YWHAZ,RIT1,SERPINH1,HTRA2,VMP1,MDH1,AUH,MYC,PMPCA,CUL3,LDHB,CUL2,PSMD1,MCM3,UFL1,EMC1,NDUFS2,HSCB,UCHL3,EEF1G,OXCT1,PSMC1,DNAJC22,DUSP9,WBP2,EXD2,PDSS2,CRY1,SDHAF4,SLC25A3,CAV2,PIH1D1,PRDX3,TMED9,ARL6IP5,CAND1,CPNE1,DCUN1D1,FZR1,ATP5PD,MYL12A,TOMM70,MRPS9,AIFM1,SSBP1,RPL12,SDHB,EEF1B2,UBXN10,TMEM70,H2AC4,GRSF1,PGAM1,COPS5,ATP1B1,NEDD8,FARSA,SDHAF1,SFXN1,EMC2,HSD17B10,NDUFS3,ATP5PB,NDUFA2,TP53,LDHA,RAB14,RPGRIP1L,SUCLG2,UQCRQ,VIRMA,CCNF,RTP4,UQCRC2,EIF4A3,CSNK2B,GANAB,PSMC5,ACAT1,GLOD4,CHCHD4,ATP1A1,UBE2H,MAT2A,RSPH1,RPL26,RPA3,SIRT7,IDH3A,BANF1,HSPB2,RNF113A,SQSTM1,LMNA,RPA2,JUP,CDK1,SAMM50,HSP90B1,H2AC7,METTL14,HNRNPH3,CYC1,MTRES1,ATG16L1,SEC22B,UQCRC1,CDC42,CFTR |
| 7.875e-12 | -25.57 | GAPDH (glyceraldehyde-3-phosphate dehydrogenase) | protein interactions | 2597 | 508 | 213 | 19454 | 5460 |
CFTR,NEK2,ARL15,UBE2M,HEXIM1,RPA2,RNF113A,PGK1,HSPB2,PML,NLE1,BAP1,CFL1,CCNB1,AKT1,RAB2A,UBE2H,TRIM23,SPOP,GLOD4,PAFAH1B3,RPS3,CSTF3,KCTD9,TP53,INSIG2,RNF8,TFCP2,DHX9,MAP1B,SNIP1,MEPCE,NUP107,NEDD8,AKAP12,GAPDH,ANKRD10,COPS5,CD81,PGAM1,DPP4,KARS1,H2AC4,CD4,SYNCRIP,SSBP1,CDC5L,ESD,GRM1,FZR1,CAND1,SEC62,AKR1A1,PIH1D1,CNDP2,NUFIP2,PPT1,CTBP1,PAK2,YAF2,EP300,HSPA8,DDX39B,ADRB2,STAU1,HNRNPA0,EMC1,UFL1,BTF3,HNRNPAB,MYC,DNAJB6,COP1,ICAM1,ATG3,TACO1,PPP5C,SNRNP40,GDPGP1,EEF2,TUBA1A,ISG15,MOB3C,TPPP,EWSR1,CDK5,PABPC1,KRAS,DDRGK1,CTNNB1,YWHAG,PPIB,GSTM3,HSPB1,CBL,POU5F1,AGR2,EED,RBM5,CCT7,HSP90AB1,CDK17,HNRNPL,CDK7,UBA52,ATG16L1,PDIA2,RPLP0,RARS1,METTL14,GRM2,JUP,LMNA,GRIA2,RPA3,SOD1,CRYZ,PIAS1,HMGB1,AR,USP14,TUFM,FBXO7,CDC73,TXNIP,MSN,METAP2,ENO1,CCNF,VIRMA,FERMT2,TXN,NDN,EEF1A1,SERPINB9,MSRB3,ILF2,PPME1,ACTR2,CAMK1,EMC2,PPP1R12A,FAF1,SMN1,PSEN1,OLA1,HUWE1,HDAC6,EMC4,CNN3,DNAJC7,SLC2A1,EFNA3,DFFA,CDK9,MDM2,CDKN1A,DET1,ANXA7,PSMA3,NMRAL1,SKP1,PYGB,CUL2,CUL3,NDUFB6,RIT1,HSP90AA1,BRCA1,DCAF4,RPS9,AP2M1,RAN,ENO2,S100A6,CHP1,MAT2B,SIAH1,ACTB,DYNLL1,TUBB,PRDX2,ERLIN2,ACTN4,B3GNT2,RAF1,NLRP2,ITGB5,CHMP4C,EZH2,PCNA,GADD45A,HNRNPA2B1,HSPD1,SAR1B,TRIM37,G3BP1,RBBP7,BPGM,ATG7,HNRNPA1,PSMD3,PIK3R1,PDIA3,PRDX1,BCL2L1,PDCD10,HNRNPD,FOLR1,CACYBP,SRSF10,PPIA,CCAR2 |
| 8.088e-12 | -25.54 | RPL34 (ribosomal protein L34) | protein interactions | 6164 | 259 | 124 | 19454 | 5460 |
COIL,G3BP2,UFL1,STAU1,HSPA8,EP300,EMC9,RPL27A,MTMR6,DES,RPL19,RPL35,RPL37A,RPS9,SEC61B,RPS26,RIT1,BRCA1,BTF3,MYC,CUL3,SFN,RPL28,G3BP1,KRAS,TNF,CDK5,TRIP4,RPL31,RPS11,POLR2C,RPL18,RPS23,EZH2,NGB,CHMP4C,SOX2,DNAJC25,B3GNT2,RAF1,MAX,RAB11B,RPL7,RPLP1,FOLR1,RPL9,RPL8,PHB1,DRG1,RPL23,AGR2,PPM1B,DDRGK1,MAP3K14,WWP2,RPL6,HSPA5,NPM3,RPS15,RPL4,FBXW7,RNF113A,BAP1,RPL27,RPA3,RPL26L1,RPLP0,RPA2,CFTR,ATG16L1,RPS14,UBA52,SEC63,RPL22,SRPK2,DAPK3,NDN,RHOJ,RPL13A,PRKRA,PTEN,RPS20,PSPC1,RPS3,CCNF,METAP2,DNAJC19,UBE2H,SPOP,RPL26,DNAJC8,PPP1CC,USP14,RPL7A,RPS13,MEPCE,VRK1,RPL23A,RPL3,SNIP1,SRP72,DNAJC2,RPL15,KBTBD4,FBP1,UBL4A,CDK4,RPSA,RBM42,KLF9,RPS16,RPL35A,CAND1,PRNP,RPL12,RCHY1,RPL32,RPS2,RPL10A,SNRNP70,RPL24,HDAC6,MOV10,ENY2 |
| 8.117e-12 | -25.54 | MRPL58 (mitochondrial ribosomal protein L58) | protein interactions | 3396 | 391 | 172 | 19454 | 5460 |
HDHD5,FAHD1,HNRNPL,RPL6,SYNJ2BP,DDX50,MRPL9,NDUFV2,NDUFB5,KGD4,VDAC1,HNRNPDL,ETFB,PDHA1,NDUFA12,MTG1,DLST,TACO1,MRPL13,ATP5F1B,RPL10,HNRNPAB,MYC,PCCB,MRPS25,MCAT,DDX39B,NGRN,MRPL34,PHB2,NDUFS2,MRPS7,RPL27A,NDUFAF3,MRPL12,MRPS18A,MGME1,COX4I1,MRPS9,SSBP1,COQ8A,SYNCRIP,DKC1,MALSU1,KARS1,TMEM70,CHCHD1,SLC25A11,MRPL52,RPL3,MRPS18B,HNRNPK,PDE12,MRPS33,MRPL47,ATP5PB,METTL15,HADH,MRPL33,UQCRC2,MACROH2A1,MRPS28,MRPS21,EIF4H,SLC25A1,NDUFAF2,MRPS16,UBE2H,CALU,OAT,DLAT,GFM1,TWNK,MRPL41,MRPL40,RPS15,NME4,GRPEL1,MRPL10,QRSL1,CYC1,HEXIM1,PHB1,GATD3,AGK,NDUFS8,STOML2,MRPS35,HMGA1,CLPX,MTRF1,MMUT,HNRNPA1,MRPL18,RHOG,MRPS26,THNSL1,HSPD1,SLC25A5,MRPS11,HINT2,ETFA,FLOT1,MRPS17,RAF1,HSDL2,ERLIN2,NDUFS6,VPS72,AP2M1,MRPL23,RPL19,NDUFAF4,PYCR1,PMPCA,AUH,NDUFB7,MTG2,MRPL16,NOA1,TAFAZZIN,HADHA,HSCB,PRDX3,ATP5PO,SLC25A3,NDUFA5,TOP1,MRPL50,SLC25A12,MRPL24,MRPS23,DBT,ATP5PD,ATP5MG,GRSF1,MOV10,SIKE1,SFXN1,SLC25A10,HSD17B10,PRDX4,MRPS18C,MRPL22,FASTKD5,NDUFA2,MRPL11,BCS1L,PPIF,NDUFS3,MRPL49,MRPL51,ILF2,EIF2AK2,MRPL53,ACAT1,CPT2,SLC25A4,PYCR2,TUFM,ATP5F1A,RPL26,DNAJC19,RPL4,MRPL17,PDHB,MRPL20,POLDIP2,RBMS2,UQCRC1,MRPS34,MTRES1 |
| 8.203e-12 | -25.53 | Small_GTPase | interpro domains | IPR001806 | 134 | 77 | 18521 | 5414 |
RHOBTB1,RAB23,DIRAS1,RAB3C,RAB22A,KRAS,RAB32,NKIRAS1,RAB1A,RAB2A,RASL10B,RIT2,RALA,RASD1,RAB6A,RASL10A,RND3,RAB40AL,RASL11A,RHOU,RAB3A,CDC42,RAP2C,RAB8B,RAB11A,RAB4A,RHOH,RAB37,RAB29,RAB27A,RAB31,RAP1A,RAB14,RAB5A,RAB30,RAB28,NKIRAS2,RHOJ,RAB3D,RAB6B,RAB9A,AGAP1,AGAP2,RHOG,RABL2B,RAB33B,RHEB,RRAS2,RHOB,RAB39B,RAB5C,DIRAS3,RAB1B,RAN,RAB33A,RERG,RASL12,RIT1,RAB11B,ERAS,RAB35,RAB13,RAP1B,MRAS,RAB9B,RAB19,DIRAS2,RAC2,RND2,RAP2B,RAB18,RALB,RAP2A,HRAS,RAB3B,RHOBTB3,DNAJC27 |
| 9.386e-12 | -25.39 | DHX30 (DExH-box helicase 30) | protein interactions | 22907 | 503 | 211 | 19454 | 5460 |
RBMS2,CDK7,KLF12,RPS14,TPT1,RPLP0,ZNF574,MTRES1,LMNA,MRPS34,GRM2,MTDH,RPA3,SIRT7,MRPL20,NF2,DGCR8,FBXW7,RPL4,TUFM,PPP1CC,PYCR2,IVNS1ABP,PRKRA,TRIM24,CCNF,STUB1,EIF2AK2,ENO1,CDPF1,METAP2,GNAI2,RPL22,RPL13A,RHOJ,AURKAIP1,APOBEC3D,NDUFA2,MRPL11,ILF2,SRP72,HSPA13,NDUFS3,RPL23A,NKRF,SFXN1,MRPS18C,FASTKD5,LAMP3,HDAC6,GRSF1,MOV10,PRR3,AIFM1,RCHY1,KRR1,SLC25A12,MRPS23,ZBTB2,MRPL50,H1-5,NDUFA5,APOBEC3C,EXD2,COIL,G3BP2,HSCB,NOP53,MCMBP,YTHDF1,ZNF668,AUH,MTG2,PMPCA,CUL3,PYCR1,RAB11A,GRB10,PSKH1,DCAF4,LMNB1,RHOB,RPL37A,RPL19,RPL35,E2F4,SART3,EZH2,NDUFS6,CHMP4C,HINT2,SRSF7,COX8A,MORC2,TRIP4,FGF3,PPAN,MRPS17,G3BP1,ETFA,HNRNPA1,MAP3K14,MTRF1,MRPS35,HNRNPD,MRPS26,LHX2,GATD3,RPL8,PHB1,NDUFS8,CDC42,AGO1,CFTR,HEXIM1,DYRK2,KLF4,RPA2,RNF113A,GFM1,RAB9A,NME4,RPL7A,IGF2BP1,UBE2H,MRPS16,RC3H2,MRPS28,FGFBP1,PSPC1,SRPK2,DUSP1,H2AX,METTL15,RPSA,TP53,HBP1,GFM2,NUPR1,RBM34,MRPS18B,RPL3,CLPB,DHX9,MEPCE,RPL17,MRPS33,COPS5,RPS2,CHCHD1,SNRNP70,MRPS9,SSBP1,MGME1,RBM42,SURF6,CAND1,RPS16,FZR1,MRPL12,MTF1,PABPC5,BET1,PIH1D1,EP300,AKAP1,NGRN,SNRPA,MRPS7,UFL1,NDUFS2,STAU1,BTF3,MYC,HNRNPAB,HNRNPC,H1-1,CDKL2,MRPS25,SMU1,TACO1,CCDC90B,DLST,CMTR1,RPL10,MATR3,SOX2,ISG15,TOP3B,MTA2,NDUFA12,FAM136A,RPL18,PDHA1,HNRNPDL,HMGN4,KGD4,CPEB1,NDUFV2,DDRGK1,IFI16,WWP2,PEX3,DRG1,RAB31,SRSF1,RMND1,HNRNPL,RPS10,RHOH,LYAR |
| 9.458e-12 | -25.38 | OGDH (oxoglutarate dehydrogenase) | protein interactions | 4967 | 225 | 111 | 19454 | 5460 |
PDHA1,ISG15,CYB5R1,EEF2,RAF1,IMMP2L,KRAS,GJB1,KGD4,VDAC1,HINT2,HSPD1,PLSCR1,MRPS26,PPP3CA,RHOG,AGR2,MTRF1,STOML2,NDUFS8,RMND1,COX14,HNRNPL,ATP6V1A,GATD3,PHB1,CSNK1A1,ATP5PO,PPT1,PRDX3,TIMM29,TOMM22,EMC1,NDUFS2,HSCB,PHB2,HSPA8,HADHA,NGRN,EXD2,SCFD1,BRCA1,PCCB,USP13,MTG2,AUH,PMPCA,ESR2,USP5,ATP5F1B,ACTB,MRPL13,VDAC2,TACO1,CYB5R3,MTG1,CCDC90B,DLST,SLC25A20,GFM2,NUPR1,NDUFS3,CAPZA2,AURKAIP1,METTL15,PREB,MTCH2,TP53,MRPL11,FASTKD5,GNG5,HSD17B10,EMC2,RAB1A,SFXN1,TMEM70,CHCHD1,HDAC6,MOV10,GRSF1,COX5A,MDM2,ATP5PD,SLC25A12,SSBP1,AIFM1,NDUFB4,CYC1,MTRES1,RPA2,UQCRC1,OGDHL,CRYZ,CERS2,PDHB,MRPL41,SLC25A51,NDUFC2,DLAT,GFM1,RPA3,NRP1,DNAJC19,ATP1B3,ATP5F1A,TUFM,SUCLG2,UQCRQ,VIRMA,UQCRC2,ENO1 |
| 9.592e-12 | -25.37 | SRP72 (signal recognition particle 72) | protein interactions | 6731 | 322 | 147 | 19454 | 5460 |
PSPC1,RPS3,METAP2,EIF2S2,SRP54,FGFBP1,SEC61A1,PRKRA,RPS12,RPS20,PYGM,ZNF622,RPL13A,RPL22,SRPK2,VIRMA,RPL7A,RPS17,USP14,EIF3G,SPOP,RC3H2,PDCD4,UBE2H,RPL27,RPA3,SIRT7,SQSTM1,DERL1,MTDH,RPS15,NPM3,FBXW7,RPL4,ZC3H15,EIF4E,BRIX1,BCL6,RPS14,TPT1,CDC42,EIF3J,RPA2,SSR1,UBE2M,RPLP0,HEXIM1,RPL26L1,SRPRA,SRP14,RPL12,PTPN1,RPL32,FZR1,RPS16,RPL35A,CAND1,RPS27L,CGAS,SURF6,CDC5L,ZBTB2,ENY2,GRSF1,H2AC4,RPL24,RPS2,RPL10A,METTL18,ABCE1,RPL23A,RPL3,DHX9,H3C1,SRPRB,RPS13,MEPCE,EIF3E,RPL17,TP53,RPSA,AURKAIP1,RBM34,ILF2,LMBR1L,EIF3K,RPL37A,RPS9,SEC61B,RPL35,RPL10,RPL19,PRRC2A,FCHSD2,ESR2,MYC,NOP16,CUL3,MLF2,H1-10,FTSJ3,BRCA1,RPS5,RPS26,RPS28,EP300,STAU1,SSR3,G3BP2,RPL27A,EMC9,NUFIP2,RPL9,RPL8,RPLP2,RPLP1,RPS10,EIF2S1,LYAR,RPL7,TMEM237,CEP19,IFI16,WWP2,RPL6,XPO1,HNRNPA1,DDRGK1,EIF3D,DRG1,HSPB1,RPL31,PABPC1,RPS24,RPL28,RPS4X,TRMT1L,TOP3B,RPL29,SOX2,RPS7,TULP3,CHMP4C,RPS11,RPL18,MOB3C,RPS23 |
| 9.624e-12 | -25.37 | GRM2 (glutamate metabotropic receptor 2) | protein interactions | 2912 | 372 | 165 | 19454 | 5460 |
MRPS26,PDZK1IP1,AHSA1,DDX1,PSMD3,PRDX1,BAZ1B,PTDSS1,XPO1,HNRNPA1,RPS10,HNRNPL,RPL7,DHX15,TMEM237,HSP90AB1,TMEM248,RPL9,PSMB5,PSMB4,TSPAN18,HP1BP3,TUBB4B,RPN1,STIM1,EXOSC3,SMARCB1,SNRPE,GNAQ,FAF2,ERLIN2,KIF2A,PSMA1,G3BP1,PSMA2,VDAC1,RPS27A,MRPS17,PSMD12,RPS4X,AKT2,HSPD1,HNRNPA2B1,BAG2,PSMD14,LMNB1,MRPS25,RPS5,SLC38A1,RCL1,PSMA4,PSMD1,MCM3,MATR3,ATP5F1B,PSMD6,TUBB,RPL7L1,PSMB6,SNRPB2,RNASEK,PRRC2A,VDAC2,PIGK,CYB5R3,SF3B4,ATP5PO,SLC25A3,HNRNPA0,TRA2B,PHB2,SSR3,PSMC1,MRPS7,CMAS,SNRPA,HSPA8,PSMA3,PSMD7,ESYT1,RPL10A,CALR,MOV10,GAPDH,TMED9,DKC1,LMAN1,CDC5L,HACD3,STT3A,AIFM1,RPL12,KRR1,PSMB1,TFRC,NHERF1,ILF2,PSMC3,UBL4A,DDX39A,LBR,RPL15,PSMA5,HUWE1,FARSA,TMEM33,RPS13,ARF4,SLC25A10,SLC25A11,TCOF1,ZC3H11A,SLC16A1,MRPS18B,RAP2C,ATP1A1,IGF2BP1,MFSD14B,EXOSC1,SMARCA5,RPF2,PSMB2,CFL1,RPL26,TXN,MGST3,TMOD3,ADRM1,RPL13A,TECR,PELP1,STUB1,UQCRC2,CDIPT,PSMA6,EIF4A3,EIF2AK2,PSMC5,CLDN9,RTRAF,GANAB,SEC61A1,MRPS28,RPS12,PTPMT1,LMNA,P3H1,JUP,SDCBP,CDK1,SSR1,STOM,HSP90B1,GRM2,TFB1M,RPLP0,RARS1,LUC7L3,RPS14,PSMC4,RPL4,BRIX1,HSPA5,MARS1,EXOSC4 |
| 9.828e-12 | -25.35 | RPL13A (ribosomal protein L13a) | protein interactions | 23521 | 509 | 213 | 19454 | 5460 |
MRPL51,SRP72,MRPL11,AURKAIP1,TAF1D,RPL15,PAK1IP1,HUWE1,VRK1,MRPS18C,RPS13,RIGI,NKRF,RPL23A,MPHOSPH10,GRSF1,SPATS2L,EMC4,HDAC6,RPL35A,TOMM70,MRPL24,RPL12,RCHY1,KRR1,PWP2,STOM,GRM2,ZCCHC17,RPL26L1,RPLP0,ZNF574,RPS14,CDK7,KLF12,NF2,MRPL17,NPM3,DGCR8,RPL4,FBXW7,HMGB1,UTP23,AATF,BRIX1,MRPL20,RPA3,CCDC106,RPL26,PPP1CC,USP14,NDN,RHOJ,RPL22,CCNF,EIF4A3,METAP2,PRKRA,RPS20,PTEN,RPS12,EZH2,NGB,CHMP4C,RPS11,SART3,B3GNT2,MAK16,RBBP7,TNF,TRIM37,RPS27A,MRPL18,RB1CC1,MRPS26,RSBN1L,LHX2,DICER1,RPL23,MAP3K14,RPL7,RPL8,RPL9,PHB1,RPLP1,HP1BP3,RPLP2,EMC9,WDR77,MRPL57,NOP53,G3BP2,DCAF4,RHOB,ZCRB1,RPS5,CUL3,ZNF668,MRPL16,RPL35,RPF1,RPL7L1,RPL19,MAD2L2,ZNF22,RPL37A,RPS9,SEC61B,DNAJC2,RBM34,UBL4A,KBTBD4,MRPL47,RPSA,H3C1,IMP4,MEPCE,RPL17,MRPL52,MAP1B,RPL3,TUBG1,RPL24,SNRNP70,NOL12,CDK12,RPS2,USP15,RPL10A,ENY2,CSNK2A1,API5,RPS16,DNAJC1,CAND1,FZR1,SPPL3,DKC1,MALSU1,RBM42,SURF6,CD274,RPL32,RPA2,ZNF770,CFTR,RPS15,MRPL40,RPL27,BAP1,PML,NLE1,RNF113A,RC3H2,UBE2H,RPF2,RPL7A,SMURF1,SRPK2,RSL24D1,PSPC1,RPS3,SEC61A1,RBMX2,MACROH2A1,PDHA1,RPS23,RPL18,TRMT1L,DNAJC25,SOX2,ISG15,RPS7,KRAS,RPS4X,RPL31,PABPC1,AGR2,MAGOH,DRG1,DDX50,WWP2,RPL6,RIOX2,MRPL9,NGDN,DDRGK1,RPS10,LYAR,EED,MRPS18A,PIH1D1,RPL27A,PAFAH1B1,UFL1,STAU1,HSPA8,RAB5A,MRPS25,FTSJ3,ICAM1,RPS26,NSA2,MYC,BTF3,THAP7,MATR3,TAX1BP1,SNRNP40,KBTBD6,RPL10,CMTR1,MRPL13 |
| 9.929e-12 | -25.34 | PSMD9 (proteasome 26S subunit, non-ATPase 9) | protein interactions | 5715 | 166 | 88 | 19454 | 5460 |
CSH1,PSMA5,SEM1,PSME1,TFPT,PSMC3,CDK4,CD2BP2,MAP1LC3B,RPS16,ELSPBP1,H2AZ1,PSMB1,DSTN,RPL24,PSMD7,RPS2,ISYNA1,OIP5,KDM1A,RPS15,RPL27,BAP1,GOLGA5,GIT2,ATG16L1,PSMC4,RPS14,PAAF1,ADRM1,TMOD3,PSMA6,RPS3,CCNF,UBE2I,GNPDA1,RPS20,PSMC5,UBE2H,CCHCR1,NCKIPSD,CSK,RPS17,XPNPEP1,PSMA1,TNF,HNRNPF,PSMA2,CPLX1,AHCYL1,PSMD12,RPS4X,PABPC1,AKT2,RPS11,MAX,CKS1B,TRAF2,HMG20A,NUF2,PHB1,PSMB4,RPRD1A,PSME2,PSMD10,PPP3CA,RPL23,MGMT,PSMD3,HNRNPA1,PSMC1,PSMA3,PSMB7,GH1,PSMB3,PSMD6,PSMD4,PSMB6,S100A6,PHF21A,PSMD14,BRCA1,LSM14B,RPS5,PSMA4,CUL3,BAG3,PSMD1 |
| 1.022e-11 | -25.31 | TRIM28 (tripartite motif containing 28) | protein interactions | 10155 | 1367 | 494 | 19454 | 5460 |
JPT1,SMARCE1,IRF1,PRPF31,ZNF250,ILK,NLRP3,HTRA2,SCFD1,BRCA1,POLR3B,SNRPD1,TUBB,ACTB,EIF4A2,STXBP1,RFXANK,SLC25A3,ANXA7,ARCN1,SERTAD2,DNAJC3,HSDL1,CMAS,MAP1S,PDIA3,HNRNPD,HAX1,MRPS26,VCPIP1,SKIC8,CDK5RAP3,RPL9,DHX15,NUP35,SRSF10,HYPK,ERLIN2,FAF2,LYPLA1,BUD23,RAF1,ZNF263,B3GNT2,SART3,RPS11,NME1,EXOSC3,PRPSAP1,PCNA,MAEA,SLC25A5,SSRP1,SACM1L,PSMD12,RPS27A,DHX16,CIAO1,HSPA14,BAHD1,AP2A1,SMAD2,YPEL5,CDC73,EIF2AK2,TUBA1B,METAP2,CCNF,VIRMA,UBE2L3,NDN,CCNA2,UQCRC1,UBA52,SEC22B,SF3A1,PCK2,HAUS2,WTAP,METTL14,DCTN4,PRIM2,RPA3,PPM1G,SOD1,DVL2,IRF7,PDHB,SUV39H1,PMM2,MOV10,ZNF688,RB1,TES,PTPN1,TFE3,ZNF7,MRPS23,MRPL24,MDM2,CDK9,EXOSC8,PHF13,TRIM6,CCT5,FBP1,AP1S2,TOPORS,NDUFS3,SFXN1,FAF1,RAB1A,VPS16,RIGI,VTA1,FARSA,VRK1,NSMCE3,HUWE1,SNRPB,BTF3,SFN,HNRNPC,CREBBP,MYC,RCL1,RPS26,PSMD14,CCT2,RRAS2,SMU1,DLST,RPL10,ALG5,NCKAP1,POLR2B,CBX5,MATR3,STAT1,TOMM22,LAP3,CNDP2,EIF4B,ACAA2,PPT1,DDX5,DDX39B,LYPLA2,EEF1G,PHB2,UFL1,CTNNB1,DDRGK1,PFDN5,CDC26,WWP2,IFI16,BAZ1B,ARMC8,POU5F1,CDC23,DRG2,WDR82,GYS1,HDHD5,FUBP3,SIN3A,ANKRA2,CCT7,SUMO2,ECHDC1,RPS10,RAB1B,HNRNPL,H1-3,TUBA1A,DHX38,RPS23,SMARCB1,PDHA1,TUBB4B,CDK5,ABCF1,CBLL1,RPS4X,CCAR1,RUVBL1,HNRNPF,PRKACB,CCNB1,SLC25A1,SMARCA5,UBE2H,SORD,IGF2BP1,EXOSC1,SEC61A1,SRP54,UQCRC2,RSL24D1,CDC42,SSR1,LSM12,NLE1,PML,MAIP1,BAP1,BCL2A1,HDAC3,LYPLAL1,TSNAX,AKAP8L,TAF9,KPNA1,RPL24,CDK6,RAP1B,UBE2N,MRPS9,MYL12A,CAND1,FZR1,TP53,STRBP,IMP3,NUPR1,GNAI3,ZFP1,CAPZA2,CBX3,DHX9,PSME1,MYD88,MAP1B,RPL17,RDH11,MEPCE,HNRNPK,PDE12,H3C1,ATP1A2,MCM4,MCM3,SAMHD1,RFC5,CUL3,PYCARD,CUL2,RIT1,LMNB1,MYO6,BLVRA,ZNF304,AP2M1,PIGK,UBE2S,PARP2,GNB1,CHCHD3,TSN,RBBP4,PPP1CB,ZNF805,RTF2,PPARG,ATP5PO,NUBP2,HADHA,CRY1,G3BP2,FTL,PSMC1,MCMBP,TRA2A,EIF3D,ATG7,KRBOX4,STOML2,MRPS35,PSMD3,CLPX,RPL23,AHSA1,CDKN1B,PSMD10,UBE2D1,GATD3,COPS2,GJA1,PHB1,PPP2CB,CBFB,SERINC3,LRWD1,SPTAN1,CCAR2,NOP58,SAP30,GFPT1,E2F4,FEN1,SSBP3,RBPJ,NGB,EZH2,UBE3A,VPS26B,FHL3,MORC2,RFC3,PCGF6,RFC2,AP1M1,MCM6,SRSF4,RBBP7,TRIM26,LASP1,USP14,TUFM,PPP1CC,KPNA6,AR,ATP5F1A,PYCR2,TXNIP,RPS20,TRIM24,UBE2I,PTEN,PRKRA,GSK3A,EIF4A3,QNG1,SLC25A4,YES1,ZNF622,CCND1,TPT1,PSMC4,RPS14,ATG16L1,SAP30BP,OXSR1,JUP,CDK1,MRPS34,LMNA,ARPC2,PRPF4,HMGB1,SMC4,NPM3,HDAC6,GMPPA,GMPPB,NFKB1,UBP1,SSU72,SLC25A12,NOP9,TOP1,ARF6,AGPAT5,DDX39A,YTHDF2,MRPL11,CCDC47,GEMIN7,PPME1,ILF2,PPP4C,HSD17B10,PC,EHD4,NSDHL,MDC1,MSH6,ZNF287,ARF4,MRPL22,RNF20,CTNNBL1,SERTAD1,PAK1IP1,THOC6,DNAJB6,POLR1B,OSGEP,SPCS3,TACO1,TIMM21,PSMD4,PAFAH1B1,LDAH,NUP62,PIH1D1,STK26,EP300,HDAC5,XRCC5,DPH6,RFC4,SAP18,STAU1,SSR3,OXCT1,EMC1,UBE2D3,UTP6,MRPL9,UBE2E2,POGK,FKBP4,AGR2,CORO1C,EED,SRSF1,TNIK,TCP1,DYNC1I2,EIF2S1,TOP3B,MTA2,KDELR1,RTCB,SEC11A,TRIM11,RUVBL2,TOP2B,CCT8,HNRNPDL,MAGEC2,KRAS,NCAPG2,RPS17,ATP1A1,RC3H2,TRIM23,ZNF655,EIF2S2,PSMC5,ZBTB33,RPS3,NMI,SRC,SUCLG2,SMURF1,ADRM1,GPX1,NTPCR,CFTR,GTF3C4,CAPN1,PPP1R8,ACACA,STAT6,HEXIM1,UBE2M,UTP15,IDH2,ZNF326,ZNF267,RPA2,RNF113A,HNRNPH2,THUMPD1,TOMM20,KDM1A,COPS5,CSNK2A1,KARS1,CDK12,RPS2,LCMT1,SDHB,GTF2B,EEF1B2,RPS16,ZMYM4,ACTR1A,H2AX,IPO8,CDK4,PSMC3,IK,NFE2L2,ARPC3,CHAMP1,MRPS18B,ABCE1,STX18,SLC25A11,NOSIP |
| 1.027e-11 | -25.30 | Ras | pfam domains | PF00071 | 134 | 77 | 17795 | 5224 |
RAP2A,AGAP2,NKIRAS2,KRAS,RAB30,RHOH,RAB35,HRAS,RASL10B,RAB8B,RAC2,RHEB,RAB32,RAB5A,RAP1B,RAB2A,RAB33B,DIRAS3,RAB28,RERG,RAB11A,RAB22A,RASD1,ERAS,MRAS,DNAJC27,RALA,DIRAS2,RAB33A,RAB6A,RAB29,RND3,RHOBTB1,NKIRAS1,RAB19,RHOU,AGAP1,RAB37,RAB18,RAB40AL,RAB6B,RAB27A,RAB4A,RAB14,RAP1A,RRAS2,RASL10A,RHOG,RAB3D,RASL12,RAB5C,RHOB,RAB13,RAB3A,RAB1B,RAB3B,RHOJ,RAB39B,RAB11B,RHOBTB3,RAP2B,RAB9B,RAB31,RIT2,RABL2B,RASL11A,RAB1A,RAN,RAB3C,RIT1,RAP2C,DIRAS1,CDC42,RAB23,RAB9A,RALB,RND2 |
| 1.071e-11 | -25.26 | DDX39B (DExD-box helicase 39B) | protein interactions | 7919 | 521 | 217 | 19454 | 5460 |
PRDX1,PDIA3,HNRNPA1,CSTA,AHSA1,LYZ,PHB1,THOC2,DNM2,RPLP1,SPTAN1,DHX15,E2F4,RAF1,GFPT1,RPN1,SNRPE,HNRNPA2B1,HSPD1,SLC25A5,TRIP4,UBE3A,BAG2,SRSF7,ETFA,TRIM37,SSRP1,ANP32B,CUL3,ACO2,PRPF31,BRCA1,LMNB1,MYO6,FYTTD1,GNG12,SNRPD2,AP2M1,SNRPD1,RBBP4,TUBB,TAB1,EIF4A2,PRDX2,SNRPB2,ERH,GNB1,MTX2,RND2,EMC9,MYL6,ARCN1,UPF3B,THOC3,TXNL1,HSCB,UCHL3,AZGP1,CALR,HM13,HDAC6,RPL12,THOC1,TOP1,CWC15,ZBTB2,NCBP2,CCT5,DDX39A,PPP1R12A,ZC3H11A,HSPE1,THRAP3,BACH1,SEM1,LSM4,MDC1,CTSD,TUFM,NONO,ATP5F1A,AP2A1,ENO1,EIF4A3,CCNF,STUB1,ALB,UBE2I,TRIM24,TMOD3,MAGOHB,COPE,VIRMA,GNAI2,TECR,MYL12B,SF3A1,ATG16L1,HSP90B1,METTL14,CDK1,JUP,LMNA,WTAP,KRT7,PRPF4,SOD1,RPA3,AATF,CTNNB1,IQSEC1,PPIB,YWHAG,HSPB1,MAGOH,ANXA4,FABP5,ZHX1,CORO1C,S100A8,EED,TCP1,SUMO2,SNRPD3,SNRPA1,HNRNPL,HSP90AB1,CCT7,DHX38,SUPT5H,UBL5,TOP3B,RPS7,TUBA1A,ISG15,CAAP1,RPL18,PABPC1,CCT8,RTCB,MYO1B,POLDIP3,RPS4X,SFN,HNRNPC,MYC,SNRPB,CHTOP,PSMD14,THOC6,PSMD6,MATR3,ESR2,PSMB3,ZC3H14,CD59,SPECC1L,XRCC5,CCDC9B,PYM1,SLU7,DDX39B,SNRPA,PEBP1,SF3B1,HSPA8,HDAC5,STAU1,SSR3,TRA2B,MRPS7,SAP18,PGAM1,RBM17,API5,GAPDH,CHCHD1,SNRNP70,SMAD4,RPS2,ALYREF,EEF1B2,FZR1,SPPL3,CDC5L,MTCH2,CAPZA2,NUPR1,GNAI3,DHX9,HNRNPK,CDC40,PSMA5,CAPZA1,CFL1,SPOP,UBE2H,ALKBH5,UQCRC2,RPS3,PHAX,MOB4,CALML5,SRPK2,MYG1,PPP1R8,SPTBN1,SDCBP,RPA2,KCNAB1,GSTP1,UBE2M,BAP1,PGK1,RBM22,CRYL1,HSPA5 |
| 1.122e-11 | -25.21 | CUL2 (cullin 2) | protein interactions | 8453 | 565 | 232 | 19454 | 5460 |
ALYREF,SDHB,EEF1B2,SYNCRIP,CAND1,RPS16,FZR1,LRRC14,KARS1,DPP4,ELOC,GAPDH,COPS5,RPL24,SNRNP70,ATP6V1D,MAP4,AKAP8L,RPS2,PSME1,DHX9,RPL3,SLC16A1,HNRNPK,NEDD8,PSMA5,CAPZA1,TP53,PCMTD2,TBC1D4,SH3GLB1,RPS3,RNF187,RCBTB1,BUB3,ROCK1,NUDT1,MAT2A,ST13,TIA1,DNAJC10,IGF2BP1,RPL27,RNF113A,HNRNPH2,GCNT3,MARS1,HSPA5,TOMM20,CFTR,RPA2,KLF4,LUC7L3,GSTP1,UBE2M,SRSF1,SERPINC1,S100A8,SNRPD3,FAM98A,HSP90AB1,PFDN5,RPL6,DDX1,CCT8,PABPC1,RBM3,ABCF1,RPL31,RTCB,EWSR1,FEM1C,HNRNPF,KRAS,TFG,HNRNPDL,RPS4X,RPL28,TOP3B,TUBB4B,RPS23,DCUN1D5,RPL18,TRIM44,TAX1BP1,PSMD4,MATR3,TCEAL1,APEX1,HNRNPAB,HNRNPC,COPS7A,SNRPB,CIRBP,YAE1,DNAJB6,OSGEP,COP1,XRCC5,SNRPA,DDX5,RAMAC,HSPA8,APPBP2,EEF1G,ADRB2,BOLA2B,TRA2B,HNRNPA0,UBE2D3,SRSF2,TRIM52,RPL27A,APOBEC3A,TRMT112,ZER1,ACTA2,RPL12,AIFM1,PTPN1,TFE3,SEC23A,DERL2,PLEKHF2,DCUN1D1,PTP4A3,MOV10,GRSF1,FAF1,RPL23A,DNAJC30,SEM1,PRDX4,RPS13,CCT5,RPL15,SOX9,EEF1A1,ILF2,CTNNA1,ENO1,POP7,CCNF,RPS20,MSN,RTRAF,CMBL,CAB39,TXN,RPL22,CTSD,TUFM,AR,NONO,BRAP,CCDC22,STK11,RPA3,SQSTM1,RPL4,MBD3,RPS14,HSP90B1,STOM,METTL14,JUP,HNRNPH3,RPLP0,MRTO4,RPL8,RPL9,CBFB,RPLP1,RPLP2,COPS2,RPL7,COPS7B,DHX15,PRDX1,CISH,FEM1B,HNRNPA1,UBE2D1,CSTA,RPL23,HNRNPD,HNRNPA2B1,HSPD1,MORC2,SLC25A5,RPS24,SRSF7,PCNA,COPS4,DLG3,CSNK1E,DCUN1D3,FAF2,SNRPE,ENO2,RAN,RPS9,AP2M1,SNRPD2,SNRPD1,TUBB,ACTB,PRDX2,RPL19,BTG3,PYCARD,CUL3,CUL2,SYCE3,MCM3,SAMHD1,BRCA1,RHOB,YWHAZ,SENP8,HSP90AA1,NSFL1C,GDPD3,SKP1,WDR77,CDKN1A,PRDX3,TIMM13,FEM1A,RNF7,SLC25A3,TBC1D17 |
| 1.128e-11 | -25.21 | RPS21 (ribosomal protein S21) | protein interactions | 6227 | 244 | 118 | 19454 | 5460 |
BAP1,RPL27,RPA3,RPL4,CDC42,RPS14,UBA52,UBE2M,RPLP0,HEXIM1,RPS12,RPS20,RPS3,PSPC1,CCNF,METAP2,CTTN,RPL22,MRPS21,RPL10L,ADRM1,RPS17,AR,DNAJC8,PPP1CC,CIAO1,RPL7A,CA2,UBE2H,RC3H2,PIP4K2C,RPL23A,RPS13,MEPCE,RIGI,RPL17,MAP2K3,RPL15,UBL4A,RPSA,SRP72,RAD23B,DNAJC2,TES,SYNCRIP,RPL12,RCHY1,RBM42,FZR1,RPS16,CAND1,PLEKHF2,RPS27L,TMA16,CSNK2A1,COPS5,KARS1,ENY2,RPS2,RPL10A,RPL24,SNRNP70,ATP5IF1,RPS28,PSMC1,G3BP2,FXR2,UFL1,PIH1D1,RPL37A,RPS9,SEC61B,TACO1,UBE2V2,ESR2,RPL19,RPL10,DYNLL1,PSMD1,RPS29,MYC,SFN,CUL3,RPS5,RPS26,RIT1,ATG3,RPS24,TRIP4,SLC25A5,RPL31,PABPC1,RPS4X,RAD21,KRAS,G3BP1,SOX2,RPS7,CSNK1E,RPS11,RPL18,RPS23,EZH2,CHMP4C,RPLP2,RPLP1,RPL9,THOC2,RPS10,LYAR,RPL7,HNRNPA1,DDRGK1,PSMD3,WWP2,RPL6,DRG1,RPL23 |
| 1.142e-11 | -25.20 | catabolic process | biological process | GO:0009056 | 1936 | 700 | 18204 | 5365 |
PEX13,PGAM1,GSTM2,FMO1,PTPN22,PDE8A,USP13,ADTRP,FUNDC1,VPS4B,DCAF11,SLC6A3,STBD1,RBM7,ACADS,CPT1B,FBXL4,CPT2,PLA2G12A,FEN1,PYM1,TST,ILVBL,RETREG3,EDEM1,USP14,PGPEP1,RNF126,MAP1LC3A,HTR2A,OAT,APOBEC3D,CYP26A1,UBE2A,CYP2F1,WDR45,HSP90AA1,WWP2,NUDT18,FITM2,GSTM3,PRDX3,APOBEC3G,FAF2,CDC20,IER3,ANAPC4,FBXO11,ZER1,ABHD12,WWP1,LIX1,NUDT5,CYP2D6,ZMPSTE24,MTM1,PSEN1,ATG9A,PLPP6,TRIM26,IDE,APOBEC3F,UBE2I,LDAH,CRAT,RC3H2,SMG5,DCTPP1,PRDX4,MCOLN1,ACHE,LYPLAL1,SMPD2,OXCT1,KCTD17,TAX1BP1,RAB1A,PIM2,ERLIN1,EMC6,KLK6,VPS28,FEM1A,MME,DFFA,ABHD17A,HMGB1,PSMD4,GID4,APPBP2,ADIPOQ,PLAAT3,MMP21,DDRGK1,SNX14,TMEM106B,ETF1,VAMP7,RAB2A,FBXO31,DBH,TRAF2,TBC1D5,RAD23B,RNF144B,MTHFS,TBC1D17,DIS3L,CAPN1,ACOT8,FBXO3,PSMD14,TRIR,UFM1,EDEM2,AMT,RIMOC1,ATG3,APOBEC3B,SH3GLB1,HSP90B1,OGG1,ECHDC1,NUDT3,DAP,GPX3,FBXW11,CHMP1B,ADORA1,PRDX2,COMT,EVA1A,DDIT3,ENO2,FBXL7,HUWE1,ENC1,SMG9,HADHA,CTSC,IDO1,HSD17B11,ATG101,UBE2D3,VPS4A,FHIT,CYGB,STX12,SESN2,RNF187,PDE9A,COP1,DCP2,GNPDA1,RNF20,GABARAPL2,HECTD1,UFD1,RAB39B,CSNK1A1,FUNDC2,NUDT7,CYP7A1,ACOX1,LIPA,CNOT7,GAPDH,PNPLA4,GNPDA2,UBE2H,CLN8,CUL2,LSM6,UPF3B,PCYOX1L,AASDHPPT,FBXO22,YTHDF2,EDEM3,RNASEH2C,UBE2G2,UBXN6,ISG20,SELENOS,DDI1,RPS27A,GABARAP,LSM4,DNASE1L1,RNF128,HSD17B10,ARMC8,GK5,PSMD12,WDR77,CRYL1,MAGOH,RNF103,SNX5,GPX1,ANXA7,GPT,IAH1,HYAL2,CTSK,CTNNB1,PSMB3,SEC61B,NRBF2,ATG4C,CYP2C8,UBE2N,TRIM24,PSMC3,SKP1,PLAA,TM9SF1,FBXL19,BAD,DERL1,GSK3A,PPP1R8,PSMD7,AKR1A1,HBM,LDLR,ENO1,PNP,OVGP1,VPS33A,RNF122,PELI1,SULT1B1,RNF14,UBE3A,RNASE6,THRAP3,CRMP1,UBB,ABHD6,OGDHL,UBE2B,RHOBTB3,MAEA,SMURF1,ABCC2,PCK2,DNM2,HADH,ETFA,ECRG4,WDR82,ANAPC2,PAFAH1B3,ENPEP,PHYH,ENTPD3,IFI27,CHMP2A,DXO,CD36,SNAPIN,BAP1,PMAIP1,ANAPC13,SDS,UBL4A,CLU,PSMA1,RNASEH1,HSD17B6,SARM1,ATG16L1,NT5C2,ATG4A,TEX264,ELOC,PNRC1,EIF4A3,HNRNPD,NAE1,CCNF,VPS16,TRAF6,CD2AP,GSTM4,NUDT12,TMEM59,RNF40,ACAT1,RAB19,URAD,TMEM74,HINT2,NUDT9,SLC25A44,CYP2C9,PML,CHI3L1,DISC1,CLPX,FBXW4,PABPC1,UBXN2B,RNASET2,ARG2,FUT9,PSMB4,SRC,SLC25A21,EXT1,XPNPEP1,MMP28,POLR2G,SQSTM1,LEP,TRIM21,AIG1,PLCB2,CHDH,PHB2,RNF121,RNF146,DTL,NUDT4,TENT2,USP30,TOM1,DLST,TRIM45,HBA1,PGM1,FAH,MAN1A2,GSTO1,TMEM208,TRIM3,FBXO44,METTL14,MGAT1,PGK1,IFI16,ETFB,FBXO7,HNMT,NFE2L2,SNX17,EXOSC3,SPSB3,SMUG1,LYPLA1,EDC3,BNIP3L,EI24,TRAPPC4,TMEM199,FEM1B,SPP1,PLA2G15,AMACR,HSD11B1,RAB1B,VAMP8,SDF2L1,GDPD3,DBR1,LDHA,RNF167,SULT1A3,C9orf72,RNF8,ISG15,FAM8A1,KLHL15,NEDD8,ZFAND2A,RLIM,PDE1A,UCHL3,TMUB2,DPEP1,OTUD7B,LSM2,RNF11,PAOX,NDFIP1,CBL,BAG3,EXOSC4,VTA1,UBXN10,CNOT6,DNAJB9,CYP1A1,DICER1,PSMB1,FIS1,HBB,BECN1,TOPORS,ZCCHC7,NR1I2,CTSB,ANAPC11,OS9,PRPF19,DNPH1,GAD2,PELO,VIPAS39,HGS,IRF8,STPG4,HERC3,MAP1LC3B,SLC6A7,YWHAH,FBXO8,RNF34,GDE1,ACADSB,PDE7A,CDC16,RGS19,AGO1,AUH,ABHD10,FZR1,PLA2G4B,ALDH1L1,RCHY1,SAT1,PSMB10,SPOP,HSPA5,HTRA2,KLHL3,NUDT1,FURIN,GALE,MOXD1,NEU1,VTI1B,SLC25A17,ANAPC15,CMA1,BLVRA,PLCXD3,RNF7,NSFL1C,BCKDK,CDK5,SH3BGRL,DDAH1,STUB1,DNAJC10,CYP4F12,CYP3A5,PSMD3,HECW1,RNF5,PPT1,TMUB1,GALC,SHMT1,ERLEC1,PDE12,PSMA2,PYGB,RNF133,CTSD,FUT8,CASC3,RETREG2,DCTD,TMEM39A,MPST,GGT7,TNFAIP1,TAFAZZIN,HSPA8,UGT1A1,TRIP4,CNOT8,HMOX2,SORD,CRBN,TP53,MAP1S,PSMB5,PYGM,MDM2,CDC26,ANAPC16,CNP,NCBP2,DDX5,FBXL14,CHMP5,CDO1,NQO1,KLHL22,APOBEC3H,SGTA,LYG2,CHMP4C,RETREG1,UFL1,SLC16A1,APOC2,SIAH1,CYP27B1,RBCK1,HINT1,CBR3,RNF139,HEXB,PSMB9,GABARAPL1,FAF1,ESD,SIAH2,AKT1,HERC4,GPC1,FKRP,PFKFB2,VPS39,EXOSC8,UBA52,PCCB,PSMA4,CALR,SKIC8,PSMD6,PSMA5,GRSF1,FBXO9,UBE2W,CNOT2,UCP2,DIO3,FEM1C,PPP1R11,GID8,TNFAIP3,SPSB1,SLCO1B3,SLCO2B1,TOLLIP,EHHADH,XBP1,UBE2D1,PCSK9,PLA2G5,TSG101,PSMA3,ACER3,SYVN1,DRAM1,DHPS,FUT1,PSMA6,PPP2CB,HECTD3,KLHL25,GPR137,GPD2,TENT4A,PAFAH1B2,SNAP29,TBC1D25,MMP14,ERLIN2,ABHD4,UBE2K,SUCLG2,CHAC2,CYP27A1,MAGEC2,RAB23,PSMB7,CHMP1A,MMP9,ACAA2,LSM5,LAMP2,TOM1L1,ENPP4,TP53INP1,USP38,HEXA,MTAP,TKTL1,MGST2,SMG8,PSMB11,ATG7,PLCB1,MMP20,DNAJC3,DNAJB2,JKAMP,UBE2S,PSMB2,SRD5A3,HM13,CRYZ,PSMB6,TP53INP2,EXOSC1,CHMP2B,PNPLA8,ASRGL1,NUDT19,OPTN,VPS18,TMBIM6,DERL2,GK2,BFAR,PSMC1,TRIM5,STK11,APOBEC3C,S100A8,HDAC6,PRDX6,FBXW7,KCTD10,UBAP1,MCAT,LGALS8,RAB33B,BIRC2,PSMC4,CNOT6L,KBTBD6,RAB33A,ABHD16B,GLUL,VMP1,TRIM32,UBE2L3,USE1,CYP1B1,ENTPD4,MYLIP,HBE1,APOBEC3A,RNF26,BPGM,RNF10,VPS54,PDE2A,RMND5B,MRTO4,PSMC5,PHF23,RB1CC1,PRDX1,RNF41,TFEB,PDE4B,ANKIB1,UTP25,APEX1,CDC23,SPOPL,PAFAH1B1,FBXL3,ZFAND2B,CYP39A1,DBT,MAGOHB,ADRM1,DECR2,GPIHBP1,LYPLA2,CACUL1,RNF148,PSMD1,BSCL2,KLF1,CUL3,CCDC47,ZNRF1,CRYM,AREL1,STX17,CAPN2,NUDT16,EIF3E,FGF23,ABHD2,PDE1B,CCAR1,SAMHD1,RNF115,PPM1K |
| 1.169e-11 | -25.17 | modification-dependent macromolecule catabolic process | biological process | GO:0043632 | 499 | 217 | 18204 | 5365 |
STUB1,FEM1A,BFAR,PSMC1,PSMD4,ANAPC13,NSFL1C,SH3BGRL,UBL4A,VPS28,HECW1,RNF5,HDAC6,FBXW7,PSMA1,PSMD3,UBAP1,APPBP2,GID4,KCTD10,FBXO31,TRIM32,UBE2L3,BIRC2,PSMC4,PSMA2,KBTBD6,ELOC,RNF144B,NAE1,RAD23B,CCNF,MYLIP,RNF10,RNF133,RNF40,FBXO3,RNF26,PSMD14,PSMC5,DISC1,FBXW4,RMND5B,PML,FBXW11,TNFAIP1,UBXN2B,TRIP4,PSMB4,CHMP1B,HUWE1,CRBN,ANKIB1,SQSTM1,DDIT3,FBXL7,RNF146,MDM2,DTL,SPOPL,CDC26,FBXL3,PSMB5,CDC23,FBXL14,CACUL1,TRIM45,ANAPC16,ZFAND2B,UBE2D3,ADRM1,VPS4A,KLF1,COP1,CUL3,RNF20,ZNRF1,HECTD1,UFD1,KLHL22,RNF148,CHMP5,RNF187,TRIM3,PSMD1,AREL1,CHMP4C,FBXO44,CSNK1A1,FBXO7,NFE2L2,UBE2H,CUL2,RNF139,SIAH1,RBCK1,FBXO22,PSMB9,FAF1,SPSB3,CCAR1,PCYOX1L,RNF115,UBE2G2,HERC4,FEM1B,SIAH2,AKT1,ISG15,RPS27A,RNF8,UBA52,VPS4B,RNF128,RNF167,DCAF11,UBE2W,FEM1C,PPP1R11,UCHL3,ARMC8,KLHL15,PSMA4,PSMD6,PSMA5,PSMD12,ZFAND2A,NEDD8,WDR77,FBXO9,RLIM,GID8,RNF11,TNFAIP3,CTNNB1,OTUD7B,FBXL4,TOLLIP,XBP1,PSMB3,SPSB1,CBL,NDFIP1,PSMB1,SKP1,PSMC3,PLAA,TOPORS,UBE2N,UBE2D1,EDEM1,TSG101,USP14,FBXL19,ANAPC11,OS9,PSMA3,HGS,GSK3A,PSMD7,SYVN1,RNF126,DERL1,PSMA6,RNF122,PPP2CB,HECTD3,HERC3,KLHL25,UBE2A,FBXO8,PELI1,RNF34,TENT4A,WWP2,UBE3A,RNF14,CDC16,UBE2K,ANAPC4,TOM1L1,RCHY1,FBXO11,USP38,PSMB7,CHMP1A,UBB,FZR1,FAF2,CDC20,PSMB10,ZMPSTE24,SPOP,SMURF1,KLHL3,UBE2B,RHOBTB3,MAEA,PSMB11,WWP1,ANAPC2,UBE2I,MTM1,UBE2S,PSMB2,ECRG4,TRIM26,PSMB6,IFI27,CHMP2A,RC3H2,CHMP2B,BAP1,RNF7,TP53INP2,KCTD17,ANAPC15 |
| 1.193e-11 | -25.15 | Small_GTP-bd_dom | interpro domains | IPR005225 | 161 | 88 | 18521 | 5414 |
DRG1,RAB33A,RASL12,RIT1,RAB11B,RAB39B,DIRAS3,RAB5C,ARF4,RHOB,RAB33B,TRIM23,RHEB,RRAS2,RAB3B,RND2,RAP2A,RAB13,RAB35,RAP1B,RAB19,ARL11,ERAS,RAB6A,EEF2,RALA,RIT2,RASD1,RAB32,RAB22A,RAB1A,MTG2,RAB3C,DIRAS1,GFM2,RHOG,RAP1A,RHOJ,RAB30,NKIRAS2,RAB28,RAB9A,RAB29,RAB37,ARL5B,RAB27A,RAB31,RHOU,RAB8B,RHOH,SAR1B,EIF5B,RERG,ARL6,RAB1B,RAN,ARL4A,ARF6,DNAJC27,RAC2,DIRAS2,RAP2B,RALB,RAB18,HRAS,RAB9B,MRAS,ARL4D,GFM1,RASL11A,RAB40AL,RND3,NKIRAS1,KRAS,RAB2A,DRG2,RAB23,RABL2B,RAB5A,RAB14,RAB6B,RAB3D,RAB3A,CDC42,RAB11A,RAP2C,RAB4A,ARF1 |
| 1.197e-11 | -25.15 | CDC42 (cell division cycle 42) | protein interactions | 998 | 1280 | 466 | 19454 | 5460 |
QSER1,PSMC5,STX10,RALA,ADRM1,ROCK1,BCCIP,MAT2A,SLC6A6,NCAPG2,DNAJC10,ATP1A1,SERPINB1,UGDH,ARHGEF6,RAB9A,SPTBN1,NTPCR,CFTR,SDCBP,RPA2,EIF2B3,USE1,PARD6A,GIT2,PRKCA,ACACA,STT3A,COQ8A,CAMLG,COMT,AKR1B1,TRIM45,ARL6IP5,FCHO2,TMPO,ILVBL,CDC5L,KARS1,SNRNP70,PALM2AKAP2,SLC25A11,ABCE1,SLC16A1,SRPRB,KPNA2,SLC6A8,CAPZA1,FKBP8,PREB,RRM1,SNAP29,RAP1A,HADH,TFRC,ARPC3,BMPR2,UGCG,FAM83B,ATP6AP2,MLF2,LAMTOR1,SPCS3,H1-10,SLC38A1,COX17,EMC1,STAU1,GNB4,GOSR2,NDUFAF3,PAK2,UBAC2,TMEM184B,SRSF1,CORO1C,RHOH,VAMP7,SYNJ2BP,PPFIBP1,TBC1D5,AGR2,HSPB1,TMEM87A,TOP2B,COA4,EFNB1,SEC11A,FGD2,KRAS,ERRFI1,STBD1,TRAF2,STMN2,UCK2,RAB4A,RND3,STUB1,VAMP3,GANAB,RPS20,RAB14,ZNF622,ARMC6,YES1,SH3BP4,RPL22,DEPDC1B,LGALS8,IVNS1ABP,XPOT,EPHA2,OPHN1,MAVS,ARPC2,MTDH,B2M,EIF5B,CERS2,TMEM209,SNRPN,EEF1E1,EDF1,CNP,PAK5,P3H1,JUP,RPLP0,SRPRA,HACD3,AIFM1,EHBP1,C2CD2,CDCA3,ATP5PD,G6PD,CAV1,TMEM199,RELL1,EMC4,HDAC6,RAB23,SLC2A1,ESYT1,TIAM1,SSX2IP,EHD4,NSDHL,LTBR,STX8,DLG1,SEPTIN7,HSD17B10,EMC2,SNAP23,THRAP3,WASL,OLA1,CTNND1,GALNT2,CCDC47,SLC29A1,LBR,ZDHHC8,CASK,SRP72,MRPL49,CLDN3,CHCHD3,GNB1,VEZT,CUL3,TOMM40,MYO6,LMNB1,CXCR4,ATP5IF1,PMAIP1,NSFL1C,ATAD1,NT5C3A,H1-5,PRDX3,ETF1,VAV2,NDUFA5,MYL6,WDR6,PHB1,GJA1,RPLP1,OCRL,SPTAN1,ERLIN1,NDUFS8,RAB11B,CLPX,TAF7,PSMD3,PRDX1,EIF3D,WDR11,RAP2B,RHOG,LYZ,NQO1,RPL23,NDUFA4,JAK1,SLC39A7,EMC8,TRIM37,ETFA,MCM6,RFC3,MARCKSL1,ACO1,STIM1,VAMP2,EZH2,PGGT1B,CYB5B,UQCRC2,NECTIN2,TRAF7,CALML5,PHAX,MACROH2A1,TXNDC12,RAB2A,SLC25A1,CFL2,ARHGAP21,ST13,GORASP2,ATP1B3,MECP2,CISD1,IGF2BP1,BAP1,SEPTIN6,LRP10,RPS15,FTSJ1,CLDND1,POLR1D,CDC42,SSR1,TFB1M,CSNK1G3,LEMD3,ITGA6,ACSL4,UBE2G2,SLC39A10,RAP1B,FLRT2,RAC2,CPNE1,TMED9,KCTD3,VTI1B,SLC38A2,STX6,LMAN1,SLITRK5,NUS1,KPNA1,MAP4,YIF1A,NEDD8,AKAP12,CSE1L,TGFBR2,TP53,CBX3,EXOC3,NUPR1,CDC42EP3,MTG1,RRAS2,STAT1,MATR3,TAMM41,LRIF1,APEX1,ESR2,MYC,HNRNPAB,BTF3,STX16,SLC1A3,MDH1,BMPR1A,PEBP1,UFL1,PHB2,EEF1G,ITGAV,PACSIN3,ABCC5,USP6NL,BET1,IL6ST,RAB35,STX5,C2CD4C,RAB1B,DDX50,IFI16,PTDSS1,WWP2,RAB5C,XPO1,YWHAG,OLR1,YWHAH,DDRGK1,TENM3,CTNNB1,ARHGAP5,CBL,GNA11,CDK5,RUVBL1,SLC20A2,VAMP8,RAB18,PAK6,CBLL1,PRPS1,MIEF1,ANAPC13,TUBB4B,CCNF,METAP2,TUBA1B,EIF2AK2,CTNNA1,SLC11A2,RPS12,COPE,TMOD3,RHOJ,FERMT2,UBE2L3,PDCD5,DEK,AGAP2,HMOX2,ARFGAP3,MAPRE1,RHOU,RPA3,SOD1,SLC7A1,YKT6,NF2,PIK3R2,CDC42EP4,RABL3,COQ8B,ARHGAP1,SEC22B,FTH1,CTDSP1,SLC12A2,PICALM,STOM,GOLGA5,SH3GLB2,CARHSP1,MEST,RARS1,HAUS2,AGAP1,HRAS,RPL12,PTPN1,PSMB1,ERCC3,GRSF1,LAMTOR2,DAG1,CDC42SE2,POR,OSBPL8,PPP1R12A,RAB1A,GARRE1,SFXN1,ERG28,FARSA,CDC42SE1,CMPK1,FAM13B,MAP2K3,MTARC2,ACTR2,NDUFS3,ALPL,ITGB8,DHRS7B,PDE6D,FAM91A1,GPR89A,LRRC8A,TUBB,LAMTOR3,NIBAN2,ACO2,PKP4,RAB11A,GSTM5,MRPL16,RHOB,SLC7A11,PAXX,SCFD1,ILK,EXD2,BIRC2,TXNL1,CDC42EP2,SRM,STX7,TOR1AIP2,DAAM1,NOTCH2,PGRMC1,VAPB,FKBP10,ELOVL1,FKBP1A,SLC25A3,TYMS,RPLP2,SNX17,ATP6V1A,EGLN3,PPIA,TMEM237,PIK3R1,RAB32,HNRNPA1,ZNF175,MAP3K11,PRPSAP1,TNF,PSMD12,AHCYL1,GOLGA7,FLOT1,MACO1,NAA15,LYPLA1,PPP2R1A,RPL29,FAF2,IFNGR1,RPN1,PCDH17,BZW2,STX12,POLR2C,JPT2 |
| 1.234e-11 | -25.12 | glioma | COSMIC cancer mutations | glioma | 16050 | 4691 | 16828 | 4835 |
ORC6,FLOT1,NR2E1,DROSHA,STARD4,THOC2,DCTD,FAM177A1,MCM4,SCNM1,PDAP1,SOX14,CEP19,CHMP4C,IGF1R,SLCO2B1,CX3CR1,MAVS,UBP1,KLHL22,RAB19,UMPS,CD1C,MRPL22,SS18,CDCA7L,CHCHD6,SIAH2,POLR1B,CER1,EPS8,RFXAP,UPK1A,HOXC4,MTM1,BIRC2,NUDT7,IFIH1,FCGR2B,FCGR1A,SCML2,DNAJC19,VGLL4,ELF5,CLDN12,GPR176,PKP4,CHKB,CCNY,CRHBP,CNOT2,OTOS,PLEKHO1,MYBL2,ZNF326,GSTM5,ERAS,GLRX2,LANCL2,APOBEC3H,PRKACB,ASB7,FEN1,CLPB,VDAC1,KLF1,ODAM,JKAMP,CLEC2B,CBR3,SEPHS2,ADD1,AR,IFI6,GSTP1,LLPH,CCL2,OR8B12,PPM1K,RNASE1,TMEM45A,CGB8,FAM43A,NLRP9,LAMP2,PTPN4,OR10P1,RIT1,CHRNB2,GPX7,SSR2,MORC2,ELOVL1,SOSTDC1,EFNA3,TPM3,SNRPB,STAT5A,COPS5,FPGT,LRRC3B,MAGEH1,EIF4A2,OTX2,FEZ1,PRDM4,PLCB2,MAP2K1,APOBEC3F,TMEM167B,HSD17B6,RNF8,PEA15,AKAP8L,EP300,ADAMTS10,TTL,TMEM70,MPDU1,VAMP8,PRMT6,PMM2,PPP3R2,PRSS12,TIMP3,CHST13,ZNRF1,CLEC18A,AQP2,SMAD1,FKBP8,GABPA,KLHL24,PPP2CB,SF3B5,RCL1,PPAN,IL2RA,SEMA4C,RABGGTB,FBXO7,SLC2A3,RPL23,CLLU1,SPIN3,ANP32A,HP,VAMP7,CTTN,STOM,CDNF,TNFRSF1B,TGFBR2,CEBPG,CAPN1,USP3,CYP2C8,METTL22,ASZ1,IFNB1,CSH1,UBL5,BTN2A2,UBASH3B,POLA2,POLB,MNS1,KIAA0513,SEMG2,CCNH,SPSB3,KANSL3,TOR1B,UGT1A1,FAM83C,LTA,MRPS9,ABCG2,PTH2,MTF1,RNF148,PRICKLE2,PPP1R1A,RPL27,MSTN,CLDN9,SYNCRIP,TRMT112,SLC35F2,VGLL2,SLC16A10,DIO1,ZNF821,GTF2H5,RPRD1A,VRTN,HINT3,SLC25A10,DDX50,PPP2R2C,BST2,STK4,SPON1,TNKS,SLC22A17,PLS3,CYP1A1,ST8SIA5,RBM38,FAM181B,NKIRAS2,ACVR1C,IL1R2,TMEM41A,KLF9,PIP4K2C,STUB1,TRAK2,SERPINB1,SRSF2,UBLCP1,GSTA1,AVPR1B,ST7,SNRK,TEX264,LRRC61,UBIAD1,GTDC1,TSNAX,POLR2B,PARL,DHRS13,RFC3,SLC7A8,GPM6B,REG1B,FBXO22,TMEM59L,EGFL7,SERPINC1,ACP5,HLF,ATP6V1A,OR10A6,OR4D2,KLF4,COPS7B,DENND2D,RNF34,ACBD6,PRDX1,FAM53B,TAF10,ATG7,TUSC1,NPW,NFKBIA,PREB,LRRC8B,ETF1,TRIM68,TMED5,HARBI1,LTB,PFDN2,TCEAL1,USP16,CLCN6,AK3,SLC25A12,HMGCS1,DDRGK1,PSMA1,RPL32,SHOC2,HDHD3,DRGX,CCR1,REN,DTWD1,NCBP2,ATXN10,SOD1,ASTN1,TBC1D13,SMPD2,TP53INP1,IQCK,AVL9,DECR2,FAF1,VEGFA,CRAT,TM4SF19,PTPN11,SOBP,NAPA,NOTCH2,GNPDA2,TMOD2,GNG10,MUL1,SMG9,CTXN1,NRN1,MAPRE1,MME,METAP2,ZFAND2A,SEC22C,NTRK2,PABPC1,GNG12,APOBEC3G,CNRIP1,OR10A4,USP15,ELMOD2,LPAR2,FKRP,SIAE,GAMT,ISX,RTN4,GLRX5,GNAZ,ARG2,DNAJB9,RNF144B,ADAM21,CLDN3,THAP7,UAP1,MGAT5B,PTAR1,CRLF3,UCN,RLIM,PTEN,INO80E,DEPDC1B,ATG4C,FRRS1,SNRNP48,GFPT1,SDHB,CENPW,RWDD3,TXNDC12,CXCL13,ABHD5,CKS2,RORB,EPHX1,RPA3,CCDC160,MOXD1,NEGR1,FDFT1,SIT1,CINP,FBXW11,CNDP2,PPFIA2,THBD,OR4D6,BCL7C,IL1A,CBLN2,NUDT12,RPL27A,TYW5,NDUFAB1,JAGN1,SNAP29,HTRA2,COX8A,LGALS8,TMEM147,USP8,PTK7,GPR171,DHX38,PGRMC1,NEUROD2,BABAM1,METTL15,IKZF5,CD247,FZD3,RHOBTB1,HNRNPA0,CHST2,NXT2,CTSC,NDUFS6,TMEM126B,DDX23,PCNA,PIK3R2,PDE1B,OPRM1,CDAN1,SPRED2,PLD3,AGPAT5,CREG2,PCYOX1L,DKC1,ARPC3,FBXO44,DNTTIP1,HR,LRRC3,SERPINA1,PMP22,OR2Y1,STX11,LARP4B,NPSR1,LMAN1,SH2D1A,SLC11A2,UBB,PPP2R5E,ANKRD34B,LSM10,HSPA13,DAAM1,LRRTM3,MRPL11,SCLT1,GRAP2,RAB27A,GPX1,TRIM15,RELL2,NPPC,PSMD4,RPS7,DHX15,OVOL1,FBXL14,RHEB,XCL1,BBS5,GANAB,RPS6KA4,TSPAN18,DDX46,PDHB,MAT2B,MLC1,ZNF664,OCRL,SLC30A7,TCF19,CCDC134,SLC6A6,GNPDA1,AFAP1L2,TMEM30A,COMMD6,KCNJ3,B3GALT1,UBL3,IRAK4,IMP3,MRPL34,NDUFB6,TMEM117,NCDN,CYP21A2,GNAO1,FASTKD5,CST11,SNX22,SFXN2,IL22,PRR3,SRSF7,PCDH17,EPCAM,STAT2,TAGLN3,SAV1,CBLL1,UBA3,GLRX,TOR3A,BFAR,TOMM22,TMEM179B,ST6GAL1,REEP3,CSTF3,HENMT1,RPL7L1,CSGALNACT2,RRM1,RBM22,RPS16,KRAS,KDELR1,TOM1L1,ZNF365,BAG3,OXSR1,ILF2,ORC5,CRIP1,ZMYM3,PSMB1,NR2F6,HERC4,DKK1,CNTN2,ASNSD1,IER2,NDUFAF3,CHPF2,CFC1,ILDR1,NLRP3,SHISAL2B,SCGB1D1,RASD1,CCS,SCG3,OLFM3,RND2,PPP1R1B,BMPR2,COMMD3,MRPL18,MFSD5,FGFBP1,POP5,PSORS1C2,G3BP1,CHAC2,METTL21A,DSTN,DAPK3,ELOVL7,DBT,RAPGEF5,TPD52,PCDHB13,RPS27A,SLC16A1,OR13C8,NUF2,TMEM101,HINT2,CHIC2,CHCHD4,LAPTM4A,FBXL19,SUFU,CCDC86,MTA2,MRGPRX3,OXTR,KCNC1,SLC38A7,PGGT1B,CD83,DNAJC7,KCTD12,UQCRQ,RPL12,ADAMTS20,GFOD2,DUSP22,SOD3,ICAM1,MTMR2,PLCL1,YWHAH,FAM187B,MRPL49,GABRB3,PABPC1L,LSM2,CCT8,TMBIM6,OR1S1,SH2D5,HMGA1,FOXI3,UTP6,TSPAN11,GGPS1,MND1,IPCEF1,AUH,ZNF267,IDE,TFRC,TTC8,HSD17B11,PPME1,ZNF177,ZNF652,C1QTNF1,FBXO11,SPSB1,RBBP9,WNT10B,DGCR6L,VIP,ETFB,LRRC8D,NTNG2,ZNF22,C1D,TFDP2,ACTR3B,MIF,ZNF189,EEF1B2,RBM15B,HRH2,AP2A1,APTX,RGMB,ZNF688,SPINT2,TMEM45B,BCL2A1,CLEC7A,APPBP2,GPR146,OPTN,KCTD11,ARPC2,GINS3,MYL12B,ENHO,IL7,ATP6V1E2,ZHX3,PID1,NECAP2,SRSF4,SH3BGRL,EXOSC3,TMEM42,SNX33,NDP,SDCBP,MED23,USP13,FGF3,DRG1,CEP85,ERLEC1,SRPRB,POLR2D,SNX12,CNTFR,KRT222,SMNDC1,NEURL2,PDP2,LGALS3,NMBR,LUC7L3,HHIP,MAP4,SMYD3,DDIT4,RAB3A,CTNND1,KPNA2,LCN12,FAM91A1,OR10Q1,YIF1A,CA8,LRRC20,EGR2,HAX1,OR1F1,RPS3,CHN2,TMEM60,CALU,AIF1,HBEGF,FOXJ3,ORMDL3,USP30,UFM1,RAD23B,ENO1,OLFM2,GNPTG,CRYL1,CHST7,SERPIND1,ORAI2,RPL24,TFPT,ELOVL6,ALOX5AP,PRDX4,SLC25A14,NUP35,ZNHIT1,MECP2,TBC1D19,CLSTN3,RASL11A,RGS6,CSTA,DCAF4L2,RPRD1B,LYPLA2,TSPO,POP7,STYK1,RNF181,CELA3B,OMG,GPD2,CYP11B2,FBXL7,LBR,PHF21A,TRMT61A,RHBDL3,CAMP,COX5A,SLC1A2,THNSL1,CAPG,OGDHL,TLR1,SAR1B,CCR5,IL12A,RHAG,BRMS1L,OR5B3,PAPOLA,DHRS1,HCST,FBXO34,ZBTB16,ANAPC16,CHORDC1,NAA15,SYBU,EXOC5,SERPINB6,FTHL17,WDR55,RALA,G6PD,ADK,F11R,PPP2R5A,TLR7,GAPT,VASH1,PTGES,ACADS,RNF128,GADD45B,STX7,SENP8,MGST2,OSGIN2,LIMS2,NECAP1,GPC4,MZT2B,HBA1,PKIA,TRIM35,TRAFD1,PPM1B,PPM1M,TP53,INMT,NFKBIL1,CRELD1,AP2M1,TAX1BP1,PRDX6,KIN,SLC25A46,HSD17B1,TMED4,HEXIM2,TBC1D17,IRF8,KPNA6,RWDD4,TOX,PTRHD1,FCER1G,BET1,CYB561,SYNDIG1,GSTM3,TSEN34,FTSJ3,DUSP6,MTHFS,SETD7,PPIF,DAG1,ZBED3,CYB5D2,RPS12,TXN,MAF1,GABPB1,ARF4,SCGB1C1,RDH12,TAX1BP3,ZNF790,CALY,PML,GABARAPL2,PSMA4,DNASE1L1,SERTAD3,ZNF250,OR10A7,EIF1B,MT3,VAPB,PNMA1,CALML5,HEBP2,SP2,CASC3,SLC6A3,TCF21,CNKSR3,SEC23A,TIRAP,MYL6,GEMIN8,RPS9,TUSC2,PSMG3,GPR173,OR5V1,TOP2B,SHISA2,MAB21L1,RAB35,KCTD10,PPP1R8,MKLN1,CCL28,VPS26A,CMTM6,EEF1E1,SMG8,TMEM50A,TAS2R39,MYC,LILRB4,FEM1A,CD40LG,PIWIL3,IL2RG,SNX1,FTH1,ALB,CCM2,SLC35F1,PSEN2,SYK,ACO2,VPS16,CLN8,SLC48A1,CDC42,TNFAIP8L3,DUSP10,BACE1,SLC38A1,TTC23,PCBD1,AGR2,CACNB3,TMEM174,MORF4L1,NLGN1,LCN8,CPSF4,AGA,CD63,DNAJC24,AKAP1,CLEC1A,PARM1,PCSK9,PSMA6,KBTBD3,AGTRAP,CRADD,PPP1R3C,KCNAB1,APBB3,MCMBP,SEMA5A,S1PR4,TMEM11,TNFAIP1,LAMP3,CNOT6,CHPF,REEP6,MATR3,ZNF473,SELL,KIAA1143,GNL1,DNAJC2,GNB1L,ATP1B3,CRYAB,PPY,ROMO1,RNF11,CYTH2,SYNGR2,TAF7,APOC4,WDR82,TLR10,OR4S2,NAB2,FXYD6,ZBTB25,CD28,CD86,PNMA5,MANBAL,ENO2,OXCT1,PSENEN,SLC2A8,ZNF704,UBE2H,FARSA,EXD2,PTPMT1,KBTBD6,CYP2R1,GOSR2,SLCO1B3,FGF23,RANBP6,G6PC3,SLC25A39,CD14,PRR5L,ZC3H11A,CCL27,SFRP1,WSCD1,ELF1,HTR1A,TMX2,METAP1,RNF40,RPS26,KDELR2,DAP,DDX1,TP53I3,DPM2,RNASE6,BRIX1,IRGQ,CFL1,KLHL3,ABCB9,FAS,ATF1,COX6A2,POLR3GL,TMPO,MAD2L2,UBTD1,RBBP4,OR5A2,PLSCR3,ARMCX3,CPLX1,COX16,CUL3,AKT3,MAN1A2,POLD4,ERVFRD-1,CCDC92,DNAJC4,EIF3D,RBP5,CHMP2B,ELOVL4,PAK6,GRB10,CSNK1E,SKA1,BHLHE40,MAP1S,PI16,BPIFB4,MRPL53,HDAC3,GLRA2,RPL29,ANAPC4,ARPP19,GDPD3,TOMM40,GREM1,LRRC4B,FABP4,COX4I1,MPHOSPH6,SDC2,FAH,CAMSAP2,ACVR1B,CTDSP2,RPL10A,AKAP17A,RAD21,RAP1B,TXNRD2,DNAJB4,C2CD2L,ACTR1A,LAT2,FITM1,SNX14,AIFM1,POLR2G,COQ10B,CARHSP1,NPC1L1,TIMM8A,KLHL9,CLIC4,NPTX1,COX11,MAGED4B,HNRNPH2,HMOX2,ADM2,AHCYL1,ALDH1A3,IZUMO4,TMEM108,BRD3,SURF6,FAR2,TESK1,DVL2,OR2AT4,TTC33,RPL39,WRAP53,MMD,KLHL26,BET1L,UCHL3,TRAPPC4,EEF1A1,GAS2,TFPI,PAAF1,PRKCA,RPL9,TST,DGCR8,RNF5,API5,TPH2,PHACTR1,SAMHD1,CRYM,SPRYD4,KCNS1,DNAJC30,P2RY12,FKBP1A,SRXN1,ZMAT2,NT5C2,DOLK,EHD3,MRPS18B,ST3GAL4,KCNJ8,SAMM50,ENC1,TRIM6,PYGB,SLC4A10,FOXP1,HOMER1,PDE8A,PSMB9,RCCD1,EXTL2,ALPL,SLC20A1,ADIPOR2,LAP3,EFHD1,C2CD2,TTC4,SCFD1,CCDC47,CACNB4,TUBG1,RPL15,GHITM,TACR3,CIB3,PRMT2,CAMK2G,TMX4,BUD31,SRP54,CCDC127,FAM89B,PEX3,RCVRN,PPP3CA,CRYGB,KCNJ11,CD200R1,FGFR1,HCRT,CAMK2N1,SHC1,OR4K1,PYGM,AGK,FBXO32,ANAPC2,SMCP,MCOLN1,PSMB5,ENPP4,CCT5,SLC39A7,SORD,SBK2,CD58,AGER,IMPACT,RAB18,IDH2,FKBP14,ZNF593,ARMCX5,PRPF4,RMND5B,PGS1,RBBP7,SLC25A21,ZBTB38,HECW1,TRIM37,NFIL3,HNRNPC,SETD5,PTPN1,SPR,PPARG,GALNT12,ARFIP1,ACTA2,SIX5,TRIM21,ARMCX2,HEY2,PCDHB8,RBM17,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,RNASET2,SPTAN1,SLC35E3,NPY2R,LRP12,PAEP,NIPA2,RABL2B,CLDN11,FAM199X,TRAPPC1,MFSD6L,LYG2,AAMP,GPBP1L1,MX2,SYN3,ZCCHC10,MTPN,WDR77,FZD4,MEST,ATP6V1G1,TSEN54,SERPINB10,TMEM215,FBXO42,ZNF24,MLF1,GTF2E2,CCL19,TBC1D10C,NKX3-2,MAGOH,JAK1,LBH,AZGP1,INO80C,HBE1,ABCB1,FGF1,AZIN1,PSME2,SMAP2,RAB3B,CDCA3,KTI12,NDST1,DHRS3,TNFAIP8L2,DEFB116,ATF4,GNG7,CTNNBIP1,GSTO2,KBTBD2,RARRES2,GRSF1,KPNA1,CSNK2A1,PIWIL4,RS1,KIT,AFTPH,OR4D9,LSM3,SUPT7L,JOSD1,P4HA2,MMP9,BTF3,CYP27A1,S100A6,DYNC1I2,LHX2,ZYX,UBAP1,CDC73,DNAJC5,TMIGD1,PACSIN3,SLC7A9,HEBP1,ALKBH4,SNAP91,MYH2,ROPN1B,VRK1,PGK1,OR8B8,IRF1,P2RY1,ING1,STRBP,NHP2,NAIF1,TRIM23,ARMCX1,UBE2A,CCT2,CHRM4,UBE2D3,ATP6V0E1,GABARAP,FGFR1OP2,GRPEL1,ELMO1,TCP11L2,PRPSAP1,LTBR,CASK,OR4D11,GAL3ST1,KIAA0232,ATPAF2,CLU,LMO4,CNIH4,GLUL,CDK5R1,NCKAP1,NRP1,APOBEC3A,ZNF397,ID4,ZNF319,SEC14L1,XAGE5,TAAR1,SLAMF9,ZMYND19,CCR6,TLR3,GPAA1,ADGB,JAKMIP1,SENP5,CYP11B1,PYDC2,GRM2,CTNNBL1,IDH3B,GALNT4,CHDH,GNRH2,LRRC69,SWAP70,HSD11B1,CYP39A1,MYL12A,ITK,EIF4H,NCR3,FAM8A1,ZNF304,MRPL24,MRPL50,SLC30A5,KLK3,SNAPIN,RAG1,ENY2,DHRS4,SLC35A1,IMMP2L,MEF2A,RMND1,MIOS,PPP1R2,FAM78A,IL15RA,OSM,SLC38A9,EHBP1,MDM2,MGP,MRPL13,GSTO1,TMEM156,PSMA3,CCDC69,GALNT1,AK2,SOCS5,CNP,RND3,B9D1,NUDT3,LYAR,PFDN5,EXOC8,UST,GNRHR2,TOM1L2,RAB11A,PPIL4,CCNI,ASMT,CDO1,CRABP2,PRRC2A,DPP10,SF3B4,DKK3,IL20RB,COMTD1,FNDC8,DLX1,AKT1,APEH,FGD2,L1CAM,FIBIN,SNX20,TLR9,POLR3H,TRIM3,C1QC,TMUB1,EDF1,ATP6V0B,TMEM219,ZNF207,MEAF6,UGCG,RPS14,LIG3,LYPLA1,ZNF671,SLC25A31,SLC17A5,CD99L2,SNRNP27,PRIM2,UBR7,SDR42E1,PDIA6,TRIM32,RNF141,KLHDC8B,PLA2G5,KLK9,ARHGAP1,DOK4,GDI2,MRPL23,GFM2,E2F6,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,S100A10,FAM200A,NFYA,DUSP1,TGFB1I1,TOLLIP,BATF,STX8,RAB3C,MTAP,PWP2,CETN3,URM1,CTSK,CACYBP,AP1G2,NDNF,DCAF8L2,ANP32B,CPT2,CHST9,WFDC13,TMED3,ACOT13,RPGRIP1L,OR2W1,CCND1,FBXO9,COX7A1,LCN6,SETD4,BMPR1A,FAF2,ARHGAP21,SCG2,RHCG,MRPL47,S100PBP,TMEM33,MPHOSPH10,AP3S2,KLF10,KIF2A,BACH1,MIA2,INPPL1,ING5,DEGS1,CRYBA2,POU1F1,CYC1,CCDC42,FCAR,NPTN,ARMC8,ENTPD4,SLC35A2,PTDSS1,ID1,BPGM,CDKN3,PPIB,CD164,SPEF1,NUP107,OR52M1,SCAMP2,NLGN2,DEK,SLC5A6,CYP4F8,PRKD3,CTSD,PGAP2,MRGPRX4,FABP5,NFE2L1,AKR1A1,SPATS2L,NOP58,MRPS25,RBCK1,MMACHC,TRAF7,DUOXA2,MTMR12,ABHD16B,RAP2B,TNFAIP3,TAPBPL,ETV6,RRAGA,SIRT7,NOL4,IQSEC1,FYTTD1,TSSC4,ALDH1L1,MAK16,NONO,POLL,SPRED1,H19,GFOD1,SIVA1,EMC4,NDUFAF2,GPR37L1,SNTA1,SNAPC1,HPCA,SV2B,ZNF805,TCP11L1,SOST,EIF4EBP2,OR2A2,NAB1,ENPEP,RTP4,ZMAT5,LSM6,SYNGR1,PROX1,PRKX,FGF13,ZNF174,USP38,USP39,CERK,SLPI,FAM13B,SNRPD2,ADCY3,DCAF5,ESR2,CWF19L1,CDK6,CTNNB1,RAB8B,SOCS2,INTS12,CYP2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OPORS,LYZ,OAZ1,FAM3C,PTP4A2,MFAP3L,SLU7,VEZT,IRF7,KLHL25,TMEM165,OR8B4,RPE,SULT1B1,TRIM26,IER3,NUCKS1,CENPL,KLRC2,TOX4,CPNE2,TMBIM1,IFT172,CYTH4,RAMP3,FXN,SUPT3H,UPRT,MECR,SGIP1,MRPS17,FEM1B,MRPL9,UBE2G2,CCR7,IGF1,RXRG,SNAP25,THUMPD1,GORASP2,TTC9C,GMPS,IL18BP,RASL12,ANXA4,GALNT2,RRAGB,SNRPE,DLGAP4,CMA1,GRIK1,LRRC8A,SSPN,GNGT2,CNPY1,HAUS2,OR5M9,ELFN2,GALC,RP9,LBX1,NKAP,RDH11,KCTD3,PIH1D1,TANK,BRAP,SYNGR3,MPG,DMPK,ELFN1,MBD3,CDC23,TMEM115,NPC2,PNPLA4,PIAS1,LRRC28,TCEA2,PARD6A,RNASEH2C,EIF1AX,HSPD1,SPG21,TIA1,SLC22A6,DDR1,TMEM81,SAP18,EXOC3,CAP2,THOC3,MX1,BOLL,PIGA,GLOD4,VPS54,SLC25A27,RBMS2,TGFB2,ATG9A,ZNF622,S100A11,RUSC2,CD9,OR1M1,GADD45A,IGFBP3,GRPR,TMEM183A,DPEP3,BTG3,TMEM229B,GNB3,HINFP,NUFIP2,CMC1,VAV2,CCDC3,ITGB8,BTG2,NR1I3,LRP10,PAIP2B,TRIM44,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,GNA11,SERTAD2,HSPA5,HSPB6,THAP8,WDR45,MPV17L2,CRYBA1,NRM,RPL10,TRIP4,STAR,SUPT5H,PDCL,SPINK9,SLC25A24,GLCE,GK5,SSNA1,IP6K1,IL2RB,PTGFR,FBXW4,P2RY4,ST3GAL2,TAS2R7,CD209,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,OR4D5,TEX261,RNF10,POLE3,KRTAP8-1,GP9,OR51E2,SRI,NCAPG2,CNPY3,APLNR,CYP4V2,POLR1D,GPR160,DTWD2,PSMD3,PLAC1,SCAND1,PSMD7,SIN3A,CDK7,RAB6A,CTTNBP2,RGN,FKBPL,ZNF428,PDE2A,CDIPT,TNFSF8,PYCR2,MED22,ARFGEF1,NOG,PMPCA,TLR8,CD40,AIP,TNFSF15,SLC6A2,CRY1,RNASE9,GADD45G,YPEL4,LDB2,TMEM107,RPA2,RGP1,CCDC90B,PIWIL1,TRAF3IP3,SRPK2,TAB2,CPXM1,UNC79,THAP1,FBXL4,CD34,PRCP,EID2B,TMEM100,DCTPP1,OR4A47,ARL4D,CITED1,TXNDC17,LIAS,NPY1R,GCLC,PSMD10,CPLX3,TNNI3K,CTU1,EPHA4,GXYLT2,KCNJ2,PSMB7,TNFAIP6,FBXW7,PLG,DMTF1,CDK12,DLK2,SPP1,FAM149B1,FRZB,CHRM3,TSR2,ARL2BP,ING2,ZNHIT6,GPR17,GPC1,PLCB1,PRSS23,TNR,OR6X1,TM4SF18,BOK,OR8H3,SLC8A1,LSM14A,CAPN2,YWHAZ,STARD3NL,ICAM2,ABHD8,RNF222,REEP4,AASDHPPT,CCNA2,TM4SF20,GJA1,MAGED2,SLC29A1,SURF2,OR4K2,GRM1,PCGF6,TAF1D,SHPRH,KCNJ10,SPATA2,ADORA1,SLCO3A1,HOMER3,MAGEB10,CXCR3,SLC25A1,STAMBP,HNRNPF,ZNF511,EHD4,CEND1,FAM81A,ICOS,NINJ1,BLCAP,ITGB5,RGL2,NDUFC2,TMEM205,TRIM34,YIPF3,LXN,TCEAL8,RPS2,CAV1,B4GALT4,SPEM1,CYP3A43,PDE4B,CCIN,UBE2L3,TTPAL,PMAIP1,EIF3G,MEPCE,HUWE1,ABHD10,CPLX2,PRND,CNTROB,FTSJ1,AKR1C1,CSNK1G3,RAB39B,MRPS11,DCAF12L2,PLSCR1,PTP4A3,HSPB2,COMMD9,STK3,CBLN1,TNKS2,LILRA2,LY6H,NT5DC1,MRPS18C,TRIM36,JAK2,PROK1,PAQR3,CREBZF,NDUFA1,GPR35,DDAH1,HFE,MCL1,FAM53C,GSTA2,TMEM127,HCAR1,RB1,TRIM29,CORO6,OIP5,DPH5,PNMA3,ZBED1,SNRPB2,LZTFL1,TFB1M,SUMO2,CCR4,CHRAC1,KLF3,TNF,GGH,NUDT9,CYGB,PPAT,IL17F,SESTD1,CARTPT,KLHL1,FOXA3,PARP2,NF2,ABHD12,BANF1,PHF13,RPL26L1,CGGBP1,COX6B2,RNF133,TMEM170A,ZNF451,PRKCE,GNRH1,WDSUB1,PRKRA,TSPAN17,DBR1,TAS2R13,UBE2E2,RHOBTB3,HGS,POLDIP3,POLR2L,FSTL1,MT1E,ELK3,CRISP1,LRRC40,DPH3,CD81,IL2,SEC13,VMAC,NBN,TNFAIP8L1,AIPL1,PEX13,TBC1D25,TYROBP,WDR11,NHEJ1,SLC35B3,FHOD3,TIMP4,ACCS,XRCC5,SNRPG,ZDHHC4,WDR5B,CDC20,IGSF11,CYP2C9,MRPS34,TRIM45,ATAD1,DUSP21,RBBP8,MGAT4A,SGMS1,SLC19A3,OLR1,FBXO8,NDST3,MPPED2,PRL,CDC7,SSX2IP,SYNPR,BCL6,GSTCD,E4F1,TMED9,GTF2F1,DLST,SNX10,CA2,SGTA,MTDH,USP6NL,ZNF263,TPPP3,HSD17B10,PRNP,CAND1,GABRA1,TMEM89,MIS12,CBX3,DR1,HS2ST1,GTPBP8,LYPD6,ELMO2,TRPC1,ASPA,BCL9,CRTC2,NPM3,TMEM38B,TSPAN15,NUDT2,PSD2,GH1,BAX,PEBP4,ATP1A3,FEM1C,COCH,COX6C,PICALM,LST1,XAF1,PIK3AP1,RPIA,VTA1,CNN3,CPT1B,ZBTB39,RBM27,ANKMY2,MAD2L1BP,TMEM47,LY96,AP1S2,APEX2,ADORA3,TAB1,SF3B1,AKR1B1,TMEM185A,PAIP2,NDUFS2,SNRNP40,FAM83B,IVNS1ABP,PIK3CA,CDH11,PSMC3,JAKMIP2,TTLL10,ATG16L1,SIGLEC5,HDAC11,DIRAS3,TP53TG5,ZNF200,IZUMO2,TPST1,HNRNPH3,LCP1,AGGF1,CSF2,PCYT1B,PRELP,KRT8,GJB1,GCHFR,CHCHD2,SKP1,LSM5,DCTN3,PRKCB,IRF2BPL,PABPC5,HCFC2,SLC25A3,RWDD1,RBM41,COPE,CKS1B,DYNLRB2,HBP1,RPL4,SEC14L5,RGL1,SUV39H1,MLH3,PCBP4,APOBEC3B,BLVRA,CRYZ,FOXC2,RAB32,PITPNA,CRYBA4,BARX2,PSMD1,MPP1,ADH1B,RANBP10,SRM,MED27,BMPR1B,OR4M1,SPDYE4,TULP3,HS3ST1,CLPX,CLP1,OR5AN1,INA,CFTR,ATG3,MYLIP,SUPT4H1,FAM174A,VPS39,PTPRZ1,IFI16,SART3,PSMB10,CDK17,TMEM39A,ART5,ATP6V1D,CDKN2D,ESD,GPR37,VWF,IFNAR1,SDR16C5,SLA2,MARCKSL1,CCL11,RPAP3,RXFP2,RAB9A,HINT1,THOC6,PYCR1,TNPO2,PLP2,DUS4L,ABCF1,SMG5,NUP62,RNF139,DYNLL1,LYPLAL1,HSDL2,OPRL1,CCND3,ARL6,RAB11B,STX5,LEMD3,CSRP1,IRF4,TBC1D16,CA12,SLC7A1,CMTM7,SPATA4,ADRB3,FMOD,PREP,SHC3,CDC26,MVD,STK38L,PIGC,ARFGAP1,CYP4F22,RPL28,CACNB2,HCFC1R1,FIS1,EDEM2,SLITRK1,DDIT3,SRP72,OAZ3,VCPIP1,TCEA1,BCAS4,HM13,SLC39A10,MCCD1,MB21D2,LCN15,PGAP3,RNF182,TIMM17A,RELL1,SMAD9,UFSP1,PTPN5,LIPA,SNRPD1,CCL24,JUNB,ALCAM,UBE3A,PDE6D,OR5K1,PDZK1IP1,OR4B1,LRFN3,TNIK,S100B,RIT2,CACNG3,ZC4H2,TADA1,CETN2,CBFB,ZC3H14,EFNA5,ASPM,SH3BP4,LEP,PITHD1,SMARCE1,FIG4,LSM12,CXXC1,RPL7A,DCTN4,SEC22A,MAP2K3,DOK5,ZDHHC24,B3GALT2,PPT1,ARF6,MRPL12,FGR,SPHK2,FAM20C,RCHY1,EZH1,ARGLU1,TECR,MRPL16,RNF7,MAP3K3,KRTAP4-1,ARL11,FHIT,MED29,UBE2I,UCP2,TMEM106B,MXD1,MFAP1,SLC41A1,LAMTOR2,PNRC1,PLEKHF2,SNRNP70,SERINC1,GLIPR2,MID1IP1,SPCS1,TDP1,RPL19,IL21,SLITRK5,SAP30,RNASE4,DDIT4L,FGF16,POU5F1,HBM,MSN,ZNF362,SLC6A7,MAGEB1,DICER1,CXCL10,FBLN5,LYRM2,FOXD3,MAEA,KIAA1958,EID2,ZNF345,TPD52L1,ZNF770,UBXN2B,DUSP18,SVIP,SMUG1,CDH7,ASCC1,METTL18,RSBN1L,GAD2,SEC61A1,TTR,ASB11,RGS1,SDHC,NOL12,RHOG,FAM83A,CDC42SE1,COX7B,BGLAP,LRRC14,ZBTB26,PDCD5,PRDX3,EMILIN1,BTBD10,EIF2B2,ZMYM6,ARF1,GNG11,HMGB1,PHF7,MRPS26,TUBA1B,CKB,THAP6,HNMT,ERRFI1,FA2H,SERTAD1,KCNIP2,ZHX1,GPR83,LPCAT3,PHTF2,ZCCHC7,PPIL3,DPAGT1,CTSA,WTAP,RPL31,SSBP2,PDCD10,GDAP1L1,LRRN4CL,NOC4L,UQCRC1,AKR1E2,CRHR1,PRPS1,OLA1,HAS3,MGST3,TSPAN3,BAD,BRS3,ZMAT3,RSL24D1,TRAF1,KCTD20,RASSF4,SERPINA3,CLK1,SKAP2,SEMA3C,DOK6,PSMB4,HERC3,DDX39B,CGRRF1,LSM4,IRF9,HSD17B8,CDR2,PTGER2,NETO1,NAA30,C9orf72,STRADB,LRP3,SIAH1,NCK1,TMEM168,ST8SIA4,USE1,TMEM220,CD200,TRIM62,ZNF655,TEX19,GPR78,HNRNPAB,ZBTB6,AHSA1,PLEKHF1,KCTD16,SLC15A1,MEA1,TAF9,SCHIP1,HMGN4,CMBL,COX7B2,CDKN1B,OR6C4,MAT2A,NMRAL1,RFX5,TMEM198,TRAPPC2L,PHOSPHO2,IMP4,HELT,PDE6A,SERPINB9,MT1X,UBE2V1,TIMMDC1,SNX11,RPLP1,MET,FZD6,POPDC3,RETSAT,SLC7A11,ADIPOR1,PRM1,GAL3ST4,GFM1,EMX2,SEC61G,CENPM,SSH3,HOXB8,DEFB1,IFRD1,ACSS2,MAP1LC3B,PDLIM3,PRSS37,CTLA4,RBM5,ATF3,RANBP1,TMEM176B,CEBPE,RPL22,DLG3,RHOU,EDC3,HAPLN2,SAP30BP,AANAT,ANKH,YKT6,VPS26B,CAMKV,F2,ARL5B,ESYT1,BIRC5,MFSD3,TRAPPC3,CSRNP3,NRGN,LDB1,WNT2,GMDS,CCDC22,NDFIP1,KDM1A,PSMG2,SNN,SNRPA1,CEP70,ARL6IP5,ANKRD46,ABHD2,CTDSPL2,GMNN,CYP26A1,TMEM87A,ISG20,NUDT1,RALB,UNC45A,FKBP2,PRSS35,TBCEL,GABBR1,ERCC3,THG1L,PDLIM4,RPF2,XBP1,TIMM13,TBC1D1,GPR34,CHRM5,NACC2,CEACAM5,NAP1L3,DRD3,MTA3,EMILIN3,CA14,DIS3L,TACR1,ARHGAP19,CEP57L1,OSBPL8,BCKDK,OR9I1,TRMT5,CYB5B,ZCRB1,MED4,NAP1L5,SEMA7A,MRGPRX1,HPCAL1,LIPT2,MAGEA4,STT3A,RBM3,RRP7A,CCDC126,RACGAP1,CORO1C,ARHGAP15,RHOH,HYAL2,UBE2S,ERLIN2,NPBWR1,PIK3CG,RPSA,ACTL6A,ACP2,GNPAT,FOSL2,NDUFAF6,TMEM126A,SETD3,GPR75,SYPL1,CHTOP,ZNF343,STARD7,DIO2,EGR1,WBP11,ZNF436,TEF,ANKRD10,SCN2B,ADD2,SOD2,PCP2,TCTA,WDR12,KLF12,MLN,MAP1B,FBXO31,VSTM2L,PIGK,PELI1,CNOT8,NEU1,AMELX,VSTM4,RAB1A,GLO1,PDCD1LG2,CD59,ECD,PRELID1,ETFA,AQP3,RIMKLB,HS3ST3A1,TICAM1,TLR5,LCN1,RFC4,PNPO,OR2D3,COTL1,GPM6A,KCNG3,CHST10,SOX9,PRSS1,APEX1,PSMC5,ITPRIPL2,GAB1,AKT2,MMP20,GTF3C4,DNM2,OR4K13,C1QL2,PLCXD3,REG1A,CLRN2,SRD5A3,DCAF16,ALG5,DEXI,STARD5,FMO1,ABCC2,SUGP1,ACTR1B,STAP1,SMARCB1,HTR2A,G0S2,OR5I1,TRA2A,SATB1,BEND6,PRMT5,GANC,ACO1,CACUL1,RALGAPA2,PCK2,PPTC7,SFXN1,UBAC2,UBXN6,KCNF1,NME2,CD4,NR4A2,SLC25A45,NOSIP,LIMD2,TRIM27,COPS2,C1GALT1C1,LGI3,EIF2AK2,GTPBP2,TSHR,SLC25A20,EIF2D,NEUROD6,AIG1,INSM2,RAB31,OR8K1,STC1,DYRK1A,DRP2,SRGN,KLHL32,INPP5K,NOVA1,MCAT,NUDCD3,SEC63,TM4SF1,IRF2,ERP29,PTTG1,BCCIP,WFDC5,CAMK1,SNX2,NOL7,TACO1,NSA2,NXPH3,SSBP3,DEFB115,REXO2,DTD1,POC1B,NTF4,GPHA2,CYB5R1,LRTM2,USP2,MYT1L,SLC39A13,CYP4F12,CPE,DCAF4,ARHGEF6,PCSK2,SCN1B,CDC40,NELL2,NDUFB5,TM2D2,OR52W1,SUB1,MT1A,CD38,PNMA2,ANKRD49,CUTA,DLAT,RMI1,CAMK2N2,RIMS3,GRM8,IL13,EIF4E2,MCM8,UTP15,OSGEPL1,HP1BP3,PACRG,TAS2R16,TLCD2,PHF12,GEMIN7,ZBTB33,BAG2,MED17,DCP2,NOB1,TMEM184C,GRAP,EPYC,SELENOT,TAAR6,BLOC1S3,PHC1,PLXNC1,UGT2A3,TMEM74,TIMM8B,IRAK1BP1,CYP3A5,CD52,LMNA,PHF1,DCUN1D3,DCAKD,PLP1,XPNPEP1,RNF41,ZNF7,MGAT4B,EXOSC4,BUB3,CFL2,SLMAP,SNX5,OR4N5,ZMYM2,KLRD1,FASLG,MSRB3,CTBP1,EIF3E,CDC42EP4,JUP,DDT,ALKBH3,EXT1,CUL2,PYCARD,SLC6A8,GHR,MED30,CXCL11,TREML1,SOCS4,MED9,ASB8,ORMDL1,INPP5E,CDC16,GNB1,GLTP,SEPHS1,ANAPC11,LACRT,TOMM7,RASGEF1C,PCMTD1,MAD2L1,CA10,MAP2K6,RHBDD3,GSTA4,RBM42,PPP5C,FOXP3,LDLR,OR7E24,VPS4B,TMEM160,STBD1,FAM110B,THAP2,IL4,TIAM1,TRIM63,PAQR9,TRIM46,GPX2,DNAJC1,HCLS1,EHHADH,GLRB,OVGP1,EMP2,LILRB1,CHID1,DISC1,RBFOX3,AVPI1,SSR1,SMARCD3,NETO2,MCHR1,SFN,ZNF596,RING1,SF3A1,GNAI3,PSPC1,TRAPPC10,FAM50B,SFTPA1,STX10,TUBB,LSM14B,COIL,ZFP64,CLVS2,VAMP3,WDR83,VLDLR,CRB3,DHRS7,TFG,CYB5A,ELOVL3,MTX2,MAEL,BSCL2,RNASEK,CDK8,PHF23,IQCF5,COX10,HRAS,SYT4,WDR20,TAGLN2,RPP14,RPL13A,TRIM8,FAHD1,IKBKB,HELLS,MITF,HTRA1,KIF3B,TMEM88,CLCA1,CNOT6L,MRPL40,GTF2IRD1,CD1E,TRMT11,SMCHD1,ZSCAN5A,VSTM2A,B4GALT7,GABRG2,TFIP11,MEF2B,PRKCQ,WASF3,RPL8,IKZF2,CLEC9A,HADH,PGM1,NAT9,SLC16A4,POGK,HNRNPA1,TRIM52,ACOT8,LECT2,NFE2,LRTOMT,SKA3,ALKBH2,RPS29,DEFB121,NCKIPSD,CTSB,COX19,SOX3,TMOD3,RPS4X,RSPH1,ZDHHC15,MAP3K12,PPIA,FBP2,PAQR8,PPP1CC,OR7D4,PEX26,BAZ1B,OR4E2,ZNF32,NOP16,KCNB1,TNFRSF9,LRRC8C,DMAP1,SCAMP5,CST3,PLEKHO2,LYZL4,BCL2L1,YWHAG,ICA1,VDAC2,DCTN6,ACVR1,MYH1,IFT57,B2M,TPRA1,TIFA,SASH3,CASP4,SLC15A2,SLC52A3,TRIM22,CYB5R4,SPOP,DEFB129,MRPL36,AMACR,NR0B1,ITM2A,ADH1A,DCK,EAF2,DCUN1D1,RPS24,MCM6,NUDT4,CYP7A1,SDS,DIRAS1,PRRT1,GINS4,ABCE1,ACTN4,GATAD1,PTGES3,RGS10,ASB1,RPS15,FBXL3,QRSL1,VIPR1,HSP90B1,PSMB11,TCOF1,LRAT,RETN,MCPH1,NKRF,ISOC1,EDDM3B,ZDHHC8,KLHL28,TPPP2,EDEM3,EGLN2,LRRTM1,RNF152,UQCRC2,MRPL33,CXCL9,RBPJ,MRPL17,DUSP9,CFDP1,ATP2B4,SIGMAR1,IFNK,LGI1,CDC5L,TMEM19,SLC35A5,HPS6,OR2F1,CH25H,CRMP1,TCP1,KCNH8,CNOT7,RABIF,ADRM1,CD80,TAF11,EMX1,PKIB,HNRNPL,UBTD2,IREB2,USP46,SMAD2,PITPNB,POLR2C,GNAQ,LPAR6,CCDC167,DBNDD1,RAD1,GIPC3,NGRN,NFE2L2,NCOA5,RUVBL2,IGF2BP1,GOSR1,PPIC,MMAA,SIKE1,NDN,ARMC6,CHCHD1,SNX3,DBH,TBC1D5,CLRN1,CTTNBP2NL,VDR,IL5,PTGDS,TNNI1,PEBP1,ADRA1A,PSMB2,CX3CL1,FGF22,CBX7,COL3A1,PAK1IP1,VAMP1,ADRB2,MYO1B,QSER1,SLC2A1,GPT,SRSF12,TLR4,SLC6A1,GPN2,P2RY10,NKX6-2,SLC38A2,PLAC9,HS3ST5,GPR22,LIN7C,SSR3,PFDN1,TAF2,SGMS2,NCSTN,ANXA7,PRR19,ANO3,UBE2N,CCL1,NGDN,CTRB2,STX16,FKBP4,PSKH1,DPPA2,PMP2,PI3,EIF5A2,SMURF1,SRSF1,ITGA2,SLC31A1,DIO3,COX6B1,LMBRD1,UCK2,FGF7,MAPRE2,CAV3,EPHA2,PRPF18,CDK2AP2,IGSF21,IFT52,PIK3R1,ACOX1,F7,FADS2,TSPAN7,KDM2A,POLD2,KLHDC8A,EXOSC8,ZNF574,SUMO1,DCLRE1C,G3BP2,OR10G3,OR2J3,LHB,DEFB124,INSIG2,CBL,HSDL1,KLHL23,WDR6,ACOT6,IL12B,ANGPT1,NCALD,COPS4,ZGLP1,KCNK17,COX17,RAB28,DDI1,CYP1B1,MDH1,ELK1,FAM168B,RALYL,MRAS,MRPL41,MRPS35,ATP6V1G2,MMP14,RAB6B,GAPDH,CBLN3,CRYGA,VAC14,CLIP3,SLC25A42,YES1,RNF208,GRIA1,PI15,HECTD3,HDAC5,FABP12,FGL2,UBL4A,SERPINB11,RPL17,GKAP1,ASRGL1,POU3F4,MFSD6,MADCAM1,MPST,PSMC4,IDH3A,JRKL,RFC5,TMEM97,NSDHL,MED13L,SLC35C1,NXT1,CHMP1A,RLN3,ANKRD50,NEO1,ESAM,HSD17B3,PCCB,PDIA2,SAP30L,RNF146,SNAP23,FAM76B,BOLA1,ELOF1,GGCX,PAQR4,CCAR1,PICK1,NTRK3,TSSK1B,STX1A,GUK1,AGAP2,FBXO3,IRF2BP1,ACHE,UBE2B,CSE1L,OR4N2,FAM3A,STAC3,MNAT1,NEK9,TNFSF10,FMO3,CDK5RAP3,CLDN6,CAPZA1,KDSR,GCC1,LRRN1,CD1B,DNAJC27,DNAJB6,ZFAND2B,B4GALT1,STARD13,AOX1,PSMA5,ATP1A1,CRKL,TGIF2LX,CNPPD1,NLRP1,FBP1,TMEM199,GZMK,RP2,CENPP,STX12,KATNAL1,TMOD1,TNFRSF14,TXNRD1,RPS11,GTPBP1,KCNMB2,GSTK1,NAE1,NDUFA12,NUDT5,ARL15,ILVBL,EGFL8,AZI2,PEX5L,CBY3,MAGOHB,COMMD2,TM9SF1,FAM118B,CBX5,ARL10,MYCT1,TRMT1L,KCNMB1,GABARAPL1,CD46,GNAI2,UCK1,CDC123,QPCTL,RBM18,TOPBP1,RPL3,MTG1,G2E3,GLRA1,C1QL3,MRPS18A,TRIM11,VMO1,PROM1,YIPF4,CSNK2B,NRSN1,HOXB1,RHOB,TMUB2,MAX,OR4K17,BOLA3,DEDD,CDC42EP2,PPM1G,FLRT2,GLYAT,GFI1,TMEM209,E2F4,MYD88,FCF1,MRPL52,PLN,CD1D,SYS1,GPR26,IL1B,BAP1,PLAA,RPRM,FUT1,DOHH,DRAP1,MEF2C,LRRC4,LITAF,ARL4A,ARFGAP3,LAMTOR3,ZNF175,SNRPD3,TP53INP2,GPSM3,STK11,TESK2,COMT,GOLPH3L,TNNT2,ELAVL4,RPS27L,SEC61A2,TMEM106A,ANGPTL2,LY6G6C,RHCE,PHAX,BAALC,FKBP10,FGF12,SEC62,RIMKLA,GPX4,EXOC1,SLC1A1,PDE9A,CCDC71,CYTH1,SLC22A12,SNAPC2,CCHCR1,RPS5,UBE2F,FOXP2,CYP17A1,UBN1,TPSG1,RAP2C,ADNP,LAMTOR1,DDX5,EIF4A3,CSTB,KLHL7,MCHR2,DET1,ZNF330,OR51A4,GTF3C3,RNF14,GPNMB,SAT2,PRRG1,DNAJC10,RGMA,RAF1,IRF6,ALG2,MBLAC2,PHKA1,SCYL2,COG1,RPL10L,MOBP,PKIG,MAMDC2,TSG101,ADCY2,DRG2,THBS3,TRUB1,SNAI2,CALR,SHMT1,HEXB,SYNGR4,PPFIBP1,CYTL1,NDUFA4,SLC45A3,OAF,FNTB,NME4,SLC6A4,PDSS2,YIPF5,TOB2,SFTPC,SLC25A23,ODC1,DSN1,ZC3H15,PLAC8,CYB5R3,SNAPC5,RPP21,NDC80,RNF26,OR10G2,RAB13,SELENOF,MAP1LC3A,GNG3,CDK5,MRPL51,PATE2,PTN,TMEM31,F10,KCNA3,SSBP1,NEK2,ZNF526,NDUFV2,NDUFB7,PC,RAB5A,APOBEC3D,RAB14,BVES,GOLGA7,TMCC1,REP15,CD79B,WASL,SDC4,SP4,OR4N4,ZBED4,DYNLT3,TLR6,CD151,RPN1,KCTD9,DLG1,P2RY11,IL3,MSX1,CHRM1,PRDX2,DPP4,MRPS33,LMBRD2,LMO3,EIF2S1,UGP2,PAX6,STAT1,ZNF507,TXNL4A,TSC22D3,NANP,USP14,CXCR6,GNA14,CISH,ZMYM4,EIF2S2,BTG1,AGPAT1,ASB3,CHMP5,HDAC6,PBLD,RNF39,CNTNAP1,ANAPC13,TMEM176A,DUSP26,EYA3,GTF2A2,ACTL9,GPR15,COPS7A,PPARA,RNF20,MICB,TOR1AIP2,NUP153,STOML2,OTUD6A,RERG,RPL35,POLR3F,FRS3,RRAS2,TPT1,SNCB,ATL1,STXBP6,TPBG,KCNQ5,DAPK1,PDE1A,LILRA1,NFYB,SLC25A17,LRWD1,ZCCHC12,ARRDC3,SESN3,CDSN,ZNF692,SLC25A44,PSMD14,TESC,THY1,YWHAB,EDNRA,TBC1D24,ST6GALNAC3,TMEM95,LEPROTL1,SYT2,SPOPL,PHB2,MMADHC,TTC1,BMP1,NR1H2,PRPF31,CKLF,CCT7,PSMD12,KCTD15,PAFAH1B1,SLC25A11,HNRNPD,PDCD1,MS4A7,SECISBP2L,RAB33B,IFIT2,CDC42EP3,RNF115,MCM3,RCE1,MGAT1,RASGRP3,ENTPD3,RGS19,RPL7,YTHDF1,TUBA1A,NAA50,FCGR2A,CELF6,SH3BP5L,MED31,LUM,CCDC85B,SEMA6C,NEUROG2,MTMR6,UNC50,ICAM3,HMX2,CHST11,RASL10A,METTL6,IFNA2,IDH1,TUFM,GNG13,OR51M1,VPS28,MPZ,KRTAP12-4,CD2AP,SRC,LANCL1,PIK3R3,CISD1,MORC4,SLC35B4,MKKS,TERT,PTGER4,TOMM20,TRAF3IP2,BAHD1,DHRS7B,IZUMO1,PEG10,PSMB6,ZCCHC17,PIP5K1A,CHRDL1,NLRP6,SCPEP1,OGN,NSFL1C,TMEM190,POLR2F,PADI2,NDUFB10,POMT2,LRRC57,PLSCR4,MOG,SCN3B,NMI,OSGEP,NDUFA2,RIMS4,NUP50,IFNGR1,HMG20A,BTF3L4,ARL6IP6,TLE1,PNOC,CYP27B1,IL15,MRPL10,YBEY,NTPCR,TMEM14B,GNG5,NIF3L1,UTS2,RRN3,DHPS,TNFSF13,FLRT3,GRPEL2,STIM1,FTL,TMC7,LRIF1,SERPINI1,PPM1D,IDO1,KLHL12,MSL2,CXCL12,FLCN,SLC25A28,SLC39A3,RSRC1,RPL35A,ZNF668,CD248,CCL20,MRPS7,ZNF575,ARHGAP5,VTI1B,SPATA6,GLT8D2,EIF4E3,MYOZ3,TCAP,ARHGAP25,DES,RIC3,LIN7B,PCDH9,ZRANB2,PSMC1,SSRP1,TTC32,PAIP1,TWSG1,OCIAD2,MED21,RLN2,OR9K2,NDUFS3,HPGDS,DNTT,OSBP,GOLGA5,MORN4,GIMAP4,RPAIN,TBC1D4,UNC119B,GABRB2,ARMC1,SYVN1,HSCB,CES5A,TFEB,GRID1,PPP1R12A,CCDC122,IL6,RERE,TLR2,FGF10,HECTD1,DYNC1I1,LGR4,SMARCA5,CNPY4,VKORC1L1,DRAM1,IL1RAP,BAK1,ATP1B1,ELK4,FAIM,GPR85,PPP2R3A,RILPL2,FZR1,SMAD4,DRD1,SLC22A8,SLC1A3,NUP37,LRRC1,TM9SF4,TCEANC2,GPBAR1,ITGAV,USP5,MXI1,FERD3L,FOXP4,RNF126,TMEM182,LDHB,RPF1,FXR2,AKR7A2,AURKAIP1,AGAP1,UBE2M,PIR,TRIM10,SLC6A12,UBE2E3,MOSPD1,ELAVL2,OR5AP2,FCHSD2,ISCU,GTF2E1,TNNC2,OR8I2,SMC4,RAB22A,AK5,CLVS1,FAU,KBTBD4,PNO1,CYP2F1,PSME1,LNX2,SNX18,TYW3,RFC2,GNB4,CPNE1,ZER1,CNTN1,ACTB,MATN4,DDAH2,UGDH,AP2S1,PGAM1,RNF121,RPS13,EPO,CHCHD3,NFKBIB,MMP21,ZNF280B,EID1,HDDC2,HSP90AA1,CD1A,LPAR1,DCUN1D5,FNDC9,PPIH,FOLR2,PDRG1,PTPN22,SOCS3,UBFD1,NAA35,GSTM2,PPP4C,PPIG,NRBF2,EFHD2,GGT7,GRXCR1,PSMA2,DNAJB2,NICN1,TMEM208,RAB30,RSAD2,GABRA2,SST,COMMD5,PFDN4,CNR1,CAMLG,PLA2G12A,NPY,ZBTB2,MFN1,DAD1,TAS1R2 |
| 1.265e-11 | -25.09 | TOMM40 (translocase of outer mitochondrial membrane 40) | protein interactions | 10452 | 301 | 139 | 19454 | 5460 |
SLC35F6,CDC42,RPA2,HSP90B1,SAMM50,CDR2,MEST,CYC1,RPA3,SQSTM1,PDHB,FBXW7,LRRTM2,TOMM20,DAD1,RAB2A,FOXA3,ATP1B3,CISD1,SAYSD1,DNAJC10,ATP1A1,CALU,STUB1,OPTN,CAB39,GANAB,RAB14,MGST3,RHOJ,CPT2,UQCRQ,MTCH2,NDUFA2,URM1,TMEM205,NDUFS3,SLC25A20,SLC25A24,RAB1A,HSD17B10,DNAJC30,SRPRB,TOLLIP,DUSP21,FKBP8,CALR,SLC25A46,BAK1,ATP1B1,POR,PSMD7,NOS1AP,SDHB,AIFM1,COX4I1,RAC2,TRAK2,MYL12A,TOMM70,FAM118B,PLGRKT,SLC25A12,TOMM22,RND2,DUSP22,UBAC2,ACAA2,FKBP1A,SLC25A3,TMEM106B,NMRAL1,HADHA,AKAP1,RNF5,UFL1,NDUFS2,PRCP,PHB2,COIL,MTG2,HNRNPC,PCCB,LAMTOR1,RHOB,FIS1,BAX,HSP90AA1,RIT1,SERPINH1,VDAC2,CYB5R3,RMDN3,TAGLN2,ATP5F1B,LAMTOR3,CHCHD3,MAD2L2,E2F4,TOMM7,TUBA1A,FAF2,EEF2,RPN1,RAB19,PDHA1,RHOBTB1,CYP2C9,NDUFA4,LDLRAD4,BAG2,USP30,KRAS,CHCHD2,VDAC1,UBE2A,KLRF1,GOLGA7,TOMM6,TAX1BP3,SYNJ2BP,MARCHF5,DDRGK1,RHOG,NCR3LG1,AGR2,AHSA1,HNRNPD,NDUFB8,HSPB1,RAB35,OCIAD2,PHB1,CORO1C,RAB1B,RHOH,NDUFS8,WIF1,NUP35 |
| 1.277e-11 | -25.08 | RCHY1 (ring finger and CHY zinc finger domain containing 1) | protein interactions | 25898 | 323 | 147 | 19454 | 5460 |
RCHY1,RPL32,AIFM1,RPL12,MRPS9,CDK6,DCUN1D1,RPL35A,RPS16,AIG1,CDK9,MDM2,ZNF24,RPL24,RPL10A,RPS2,NKRF,HSD17B10,DHX9,RPL23A,RPL3,HNRNPK,SRPRB,NUP107,SERTAD1,CAMK2G,H3C1,PRDX4,RPL17,RPS13,ARF4,RPSA,TP53,RPL15,KRIT1,SERPINA1,ILF2,TUBA1B,STUB1,PELP1,UBASH3B,RPS12,RTRAF,RPL13A,COPE,DAPK1,RPL7A,SMARCA5,CDC16,AR,RPL26,BRAP,RPS17,CALU,HOXC4,ATP1A1,RPL27,DDX46,AOX1,RPL4,RPS15,GTF2I,BRIX1,GRPEL1,SNRPN,RPS14,SF3A1,ZNF326,COX6C,LIMS2,SRSF1,RPL9,RPL8,KRT8,RPLP1,LYAR,RPL7,RPS10,HNRNPL,DHX15,RPL6,TRIM8,F7,HNRNPA1,UBE2D1,RPL23,DICER1,MRPS26,CDKN1B,DDX1,HNRNPD,ABCF1,PABPC1,AKT2,SLC25A5,HSPD1,RTCB,RPS24,EWSR1,RUVBL2,SEMA4C,RUVBL1,KRAS,HNRNPF,ANP32B,RAD21,SSRP1,RPL28,RPS4X,RPS7,HOXB1,RBM38,PPP2R1A,TMBIM1,RPN1,RPL18,DCUN1D5,RPS23,SART3,SERPINA5,RPS11,RPS9,SNRPD2,RPL37A,RPL35,MATR3,ATP5F1B,SNRPB2,RPL19,RPL10,RAB11A,HNRNPAB,MYC,FTSJ3,LMNB1,BRCA1,RPS5,COP1,HADHA,DDX5,SF3B1,TGIF2LX,HNRNPA0,MRPS7,MT2A,PGRMC1,RPL27A |
| 1.280e-11 | -25.08 | RTN4 (reticulon 4) | protein interactions | 57142 | 312 | 143 | 19454 | 5460 |
TP53,HADH,HUWE1,RAB3B,SOCS2,RIGI,RDH11,ABHD10,SLC25A10,RAB1A,BACE1,TCOF1,HSD17B10,EMC2,POR,ESYT1,TMEM70,OSBPL8,RAB3A,EI24,DHRS7,ATP1B1,DNAJC1,ARL6IP5,PLEKHF2,DERL2,TMPO,ITGA6,AIFM1,PTPN1,HSD17B11,CLN8,RPA2,LMNA,METTL14,GPR35,WWP1,SSR1,TM9SF1,EPHX1,SEC22B,UQCRC1,HSPA5,CCR4,DDX46,RPA3,PRPF4,PML,SYVN1,DERL1,SQSTM1,RTN4,RAB9A,SMPD2,ATP1B3,EIF3G,SPOP,ENDOD1,NAPA,OAT,ATP1A1,NDUFAF2,RAB2A,CIAO1,CNTNAP1,CFL1,HMOX2,RAB14,SEC63,VIRMA,UQCRC2,CCNF,ATL1,CHRM4,SCAMP2,SNX12,RPN1,STIM1,RAB4A,PTRH2,CYB5B,PLD3,TMT1B,E2F4,LPAR6,DNAJC25,SOX2,ERLIN2,SPG21,VDAC1,RAB18,SLC25A5,TMEM88,TMT1A,RHOG,FAM241B,AGR2,BCL2L1,TMEM208,PTPN5,CTNNB1,FAM241A,RAB1B,SNX2,SNX1,SLMAP,RAB33A,RAB11B,KCNA2,CYB5A,CTBP1,ATP5PO,VAPB,ACAA2,PRR13,PGRMC1,SEC62,FXR2,EMC1,STAU1,SSR3,STX7,TACR3,RNF11,RNF41,HSDL1,TSPAN15,RABAC1,EP300,RAB5A,CIRBP,CRMP1,RAB11A,ATG101,CAVIN2,REEP4,FBXO22,ESR2,LMBR1L,MOG,CYB5R3,RETREG3,SEC61B |
| 1.346e-11 | -25.03 | regulation of response to external stimulus | biological process | GO:0032101 | 1116 | 430 | 18204 | 5365 |
PDE2A,IL2RA,TASL,MAP2K6,PSPC1,CCL2,ALOX5AP,ARG2,DRD1,KCNJ8,SPATA2,MIR16-1,MIR141,NFKB1,TRAF6,TLR2,RARRES2,MIR222,TLR10,TICAM2,SLC12A2,THBD,CLEC12B,XRCC5,TBK1,CYRIB,TRIB1,RNF26,NINJ1,DPP4,TLR5,CCL19,VAMP3,SMAD3,CERS2,NT5C2,SARM1,TRIM62,LACRT,SELENOK,BIRC2,DUSP1,YES1,KLRC2,RHBDD3,CCN3,TRIM32,MIR920,PIK3AP1,OTULIN,FGF16,SYK,MIR205,CCR4,NLRP1,CREB3,PSMA1,STAP1,TRIM5,NFKBIL1,HDAC6,S100A8,FCGR2B,MIR181C,PPM1B,TLR1,IL15,TICAM1,NFE2L2,SAMHD1,RNF115,UBASH3B,BMPR2,IL23A,SEMA7A,VEGFA,IRF1,TRIM3,PQBP1,CCL1,YWHAZ,OSM,PIK3R1,ZNRF1,SETD4,BPIFB1,TLR8,IFI16,NTRK3,SERPINC1,AREL1,IFNG,F7,TIAM1,CD47,IL17F,MIR15A,LGR4,P2RY12,PDCD4,TRIM45,NEO1,SRC,PSMB4,MMP28,IL18,PIK3CG,CD200,NECTIN2,TRIM21,MIR140,LEP,SQSTM1,PHB2,TFPI,HEXIM1,BACE1,FGL2,ACP5,STAT1,NR1H2,FGF1,PLA2G5,TIRAP,NRP1,MIR187,MCPH1,PTEN,JAK2,RGMA,DEFB114,LACC1,PRKCE,MIR206,CD14,EIF2AK2,IL22,MET,KLRD1,SOD1,CNR1,IL2,PAK2,MIR221,KARS1,CALR,EP300,NFKBIA,IGF1,CCL24,KLK5,GPX1,TNFAIP3,HYAL2,GSTP1,NOP53,AKT1,IL1B,SELENOS,ITGA2,DRD3,NCR3,TLR6,CLEC6A,MIR204,SERPINB9,NMI,LYAR,SIN3A,RIGI,CASP12,POLR3F,BAP1,OPTN,CD36,MGST2,SH2D1A,PROS1,TNFRSF1B,TLR9,IFNK,RTN4,MIR21,LPCAT3,CD9,FABP4,LILRA2,SFN,UBE2K,FGR,POLR3B,DUOXA2,IL12B,FOXP1,MACIR,MIR223,PYDC2,MMP9,PADI2,TRAF3IP2,USP38,ENPP4,RSAD2,IL6,CD274,FOXP3,HSPD1,LDLR,MATR3,PSMA6,FLOT1,PPARA,PELI1,VEGFC,OXSR1,MIR105-1,TMSB4X,CXCL10,VAMP2,LSM14A,CGAS,MIR424,NPY5R,NLRP2,RB1,CASP4,EIF4E2,NLRP3,AIPL1,PRKCA,MIR17,PLSCR1,MIR657,TMEM126A,MAPKAPK3,CLDN3,TIFA,IRF4,F2,CCR2,AIF1,CX3CL1,MIR1298,IL10,MUL1,XCL1,CAMK2N1,ADIPOQ,TNF,VAMP7,LY96,TRIM6,PHB1,MIR145,CX3CR1,CXCL12,BCL6,YTHDF1,HMGB1,CD1D,MBL2,ABHD17A,FEM1A,PLG,PYCARD,MIR361,AGER,DUSP10,CD226,EMILIN1,CXCR4,IKBKB,IL34,TRIM44,TRIM15,CNOT7,C1QTNF1,TPBG,ATAT1,DROSHA,MIR195,YTHDF2,MIRLET7G,TNFAIP8L2,IRAK4,UFD1,STK24,PTGER4,CSNK1A1,UFL1,CXCL13,SLC15A2,PPARG,IDO1,CTSC,ST6GAL1,LPAR1,CXCL8,MIR34A,NEK7,IL13,TNFAIP6,IL21,CLEC7A,ADORA1,PTPN1,HSPA8,FGFR1,MIR26B,PRDX2,RAC2,SEC14L1,NONO,MPP1,TLR4,TOMM70,MICB,ST3GAL4,KLF4,MIR590,PTPN11,MIR708,CD200R1,MIR200C,USP14,NLRP6,TLR7,IRF7,FCGR1A,MIR488,TRAF3IP3,OAS1,CCDC92,LTA,CCR1,MAP2K1,TNR,FAM3A,NDFIP1,CTNNA2,STAT2,TRIM22,MIR20A,GHRL,CCL21,BANF1,IFI35,BECN1,FCN2,CLPB,DUSP3,MIR144,SLC6A3,FGF10,DHX9,VAMP8,TRAFD1,SPP1,PTPN22,CREBBP,ADTRP,HCFC2,GREM1,CCR6,SEMA5A,CCR7,CDH13,ISG15,KLK3,TAB1,MAVS,FURIN,TRIM11,IFNB1,CAV1,CPTP,SOCS3,TYROBP,MSTN,LYPLAL1,FKBP1B,SWAP70,CD28,TAX1BP1,CMA1,MYD88,MIR31,ABHD12,IL4,IFIH1,GFI1,SOCS5,IL20RB,ZMPSTE24,PTN,NLRP9,CD81,MIR146A,MIR149,APOBEC3F,DEFB124,EPHA4,TLR3,LRRC14,CASK,GPSM3,CCL5,GPR17,MIR142,APOBEC3G,HSPB1,NUPR1,PTGES,IGF1R,MIR126,IER3,SCG2,IL12A,HTR2A,DDT,BCL10,ELMOD2,LILRB1,CCL3,MIF,RNF34,IL6ST,HSP90AA1,IRF3,USP15 |
| 1.356e-11 | -25.02 | USP11 (ubiquitin specific peptidase 11) | protein interactions | 8237 | 525 | 218 | 19454 | 5460 |
HSP90AA1,MYO6,BRCA1,LMNB1,MCM3,RBM15B,SAMHD1,RAB11A,GRB10,CUL3,ALDH1L1,SNRPB2,PRRC2A,RBBP4,TUBB,PRDX2,FOXP3,VGLL4,SLC25A3,MYL6,NDUFA5,CDKN1A,MTX2,NRBF2,CDSN,DUSP26,NPTN,HSCB,CRY1,TRUB1,EXD2,LYZ,HNRNPD,SKIC8,TRA2A,HSPB8,DPY30,DYRK1B,PRDX1,DHX15,NDUFS8,PPIA,FBXO32,PHB1,WDR6,CYB5B,NDUFS6,RPN1,TULP3,NUP153,FAF2,FLOT1,RBBP7,PCNA,HSPD1,STK11,AP2A1,ZNHIT3,IVNS1ABP,TDP1,NONO,PPP1CC,ATP5F1A,CIAO1,VIRMA,GNAI2,TXN,TMOD3,PTEN,MSN,TRIM27,CTNNA1,ENO1,PELP1,CCNF,PTP4A2,UQCRC1,SIPA1L1,TPT1,UBA52,CCND1,PSMC4,PCK2,ATG4C,MBD3,PIK3R2,SIRT7,RPA3,DNAJC7,SSX2IP,TCEAL9,ARL2BP,SLC2A1,PROM1,ATP5MG,MOV10,PTP4A3,CITED1,SEC23A,DECR2,ACTA2,SRP72,NDUFS3,MAP2K3,EEF1A1,DDX39A,CCT5,RIGI,THRAP3,FARSA,SNAP23,RING1,SFXN1,PPP1R12A,FAF1,H1-1,POLR1B,PHF7,CCT2,MLF2,PSMD1,MYC,DES,TCEAL1,MATR3,ATP5F1B,ZMYM2,MIDEAS,EFHD2,VDAC2,EIF4B,SAP18,MSX1,EYA3,EEF1G,HNRNPA0,DDX5,PCGF2,RAB5A,HSPA8,XRCC5,RFC4,DDX1,CTNNB1,XPO1,CNOT8,NDUFV2,HMG20A,HSP90AB1,SUMO2,TCP1,OSBP,CORO1C,SRSF1,MTA2,PNMA2,TUBB4B,FOXJ3,EEF2,NCSTN,POLDIP3,VDAC1,PSMA1,KRAS,HNRNPF,ICAM3,SETD4,MYO1B,TOP2B,CCT8,ATP1A1,DNAJC10,ATP1B3,TIA1,CFL1,RSPH1,BUB3,SEC61A1,UQCRC2,KLF4,HEXIM1,WRAP53,RPA2,SPTBN1,HSPA5,LCP1,PGK1,LSM12,HNRNPH2,PML,BAP1,USP15,RPS2,SHC1,BECN1,CHCHD1,GAPDH,TPM3,ZNF24,TMPO,DKC1,CAND1,CD4,ADD1,GNAI3,NFE2L2,H2AX,CD38,MTCH2,TP53,CAPZA1,HNRNPK,KPNA2,NEDD8,DHX9,ABCE1,SLC16A1,ATP2B4 |
| 1.368e-11 | -25.02 | PSMB1 (proteasome 20S subunit beta 1) | protein interactions | 5689 | 326 | 148 | 19454 | 5460 |
PSME1,MAP1B,TFPT,HSD17B10,HNRNPK,TOLLIP,PSMA5,CAMK2G,SEM1,FKBP8,PSEN1,PSMB10,CCT5,INSIG2,UBE2V1,PSMB9,PSMC3,RAD23B,NUPR1,RNF8,SMAD3,MRPS9,PSMB1,MAPRE2,FZR1,KARS1,RPL24,PSMD7,PSMG2,ZNF688,RPL10A,USP15,BAP1,RPA3,PGK1,SYVN1,DESI1,OIP5,NME4,PSMC4,SF3A1,PAAF1,CFTR,CDC42,GRM2,RPRD1B,RPA2,HAUS2,UBE2M,HEXIM1,PSMA6,CCNF,UBASH3B,PSMC5,TRIM27,SNX3,ADRM1,TRAF1,VIRMA,SEC13,PTPN11,RPL7A,PSMB2,MAT2A,AR,USP14,FBXO7,TRIM23,RC3H2,MAPRE1,ZNF177,PSMG3,UBE2H,HNRNPA2B1,UBE3A,PSMA1,KRAS,PSMA2,DCP2,UFM1,FANCG,RAB8B,RPS27A,UBE2A,PSMD12,KHDC4,DSTYK,ISG15,SOX2,TRAF2,CHMP4C,STMN2,RPS23,OTULIN,FAM136A,SMARCB1,PSMB5,PHB1,PSMB4,PSME2,SNRPD3,SNX1,CCT7,HMG20A,EGLN3,CYTH4,PSMD3,DDRGK1,AGR2,PSMD10,YWHAB,MED4,CDKN1B,JAKMIP1,FAM50B,IMPACT,PSMA3,EYA3,LZTFL1,SRSF2,UFL1,SKP1,PSMC1,DDI1,NOTCH2,PSMB3,PRDX3,PSMB7,THAP6,MBL2,PSMD6,LDB2,PSMD4,CLIC4,PSMB6,PSMA4,LIN7B,MYC,TTC33,BAG3,CASP4,RNF40,PSMD1,OTUD7B,PSMD14,POMP,RIT1,GTPBP2 |
| 1.461e-11 | -24.95 | protein catabolic process | biological process | GO:0030163 | 715 | 293 | 18204 | 5365 |
FBXL4,OTUD7B,TNFAIP3,CTNNB1,GID8,RNF11,CTSK,FBXO9,NEDD8,WDR77,ZFAND2A,RLIM,PSMA5,PSMD12,PSMD6,ARMC8,KLHL15,CALR,PSMA4,SNX5,RNF103,TMUB2,PPP1R11,FEM1C,UCHL3,UBE2W,DCAF11,DDI1,RNF167,SELENOS,UBXN6,GPC1,VPS4B,RNF128,UBA52,FAM8A1,RPS27A,RNF8,ISG15,SDF2L1,AKT1,SIAH2,FEM1B,HERC4,UBE2G2,DERL1,RNF126,SYVN1,PSMD7,HGS,GSK3A,PSMA3,PRPF19,OS9,PCSK9,CTSB,ANAPC11,FBXL19,PGPEP1,TSG101,USP14,EDEM1,TRIM24,UBE2D1,UBE2N,DNAJB9,UBXN10,TOPORS,PLAA,PSMB1,SKP1,PSMC3,BAG3,SEC61B,NDFIP1,CBL,SPSB1,PSMB3,XBP1,TOLLIP,CDC20,FZR1,FAF2,ABHD10,CHMP1A,UBB,PSMB7,ZER1,RCHY1,USP38,FBXO11,LAMP2,TOM1L1,ANAPC4,CDC16,UBE2K,ERLIN2,WWP2,RNF14,UBE3A,MAGEC2,PELI1,RNF34,UBE2A,FBXO8,KLHL25,HSP90AA1,LDLR,SLC6A7,HERC3,RNF122,PPP2CB,HECTD3,PSMA6,KCTD17,ANAPC15,TP53INP2,LYPLAL1,ERLIN1,PMAIP1,RNF7,BAP1,CMA1,CHMP2B,RC3H2,CHMP2A,IFI27,PSMB6,ECRG4,UBE2S,PSMB2,TRIM26,DNAJB2,JKAMP,DNAJC3,MTM1,PSEN1,MMP20,UBE2I,HM13,ANAPC2,IDE,MAEA,WWP1,PSMB11,RHOBTB3,UBE2B,KLHL3,HTRA2,SMURF1,HSPA5,SPOP,PSMB10,ZMPSTE24,KBTBD6,ELOC,PSMA2,PSMC4,TMEM106B,BIRC2,ERLEC1,UBE2L3,TRIM32,FBXO31,TRAF2,KCTD10,TMUB1,GID4,PPT1,APPBP2,UBAP1,PSMA1,PSMD3,FBXW7,HDAC6,RNF5,HECW1,UBL4A,DERL2,VPS28,SH3BGRL,ANAPC13,NSFL1C,PSMD4,PSMC1,CLU,ABHD17A,BFAR,DNAJC10,FEM1A,STUB1,MME,UBXN2B,TNFAIP1,FBXW11,HSP90B1,PML,RMND5B,FBXW4,CLPX,DISC1,PSMC5,PSMD14,RNF26,CTSD,RNF133,RNF40,FBXO3,EDEM2,RNF10,CCNF,MYLIP,RAD23B,NAE1,USE1,CD2AP,RNF144B,ADRM1,VPS4A,UBE2D3,ANAPC16,ZFAND2B,CACUL1,TRIM45,FBXL14,LYPLA2,CDC23,PSMB5,CTSC,RNF121,FBXL3,CDC26,SPOPL,MDM2,RNF146,DTL,FBXL7,TRIM21,SQSTM1,DDIT3,RNF41,ENC1,ANKIB1,UTP25,HUWE1,CRBN,CHMP1B,HSPA8,PSMB4,EXT1,TRIP4,BNIP3L,RNF115,LYPLA1,PCYOX1L,SPSB3,CCAR1,TMEM199,FAF1,PSMB9,EDEM3,FBXO22,RBCK1,SIAH1,CUL2,RNF139,CLN8,UBE2H,FBXO7,NFE2L2,CSNK1A1,FBXO44,SGTA,LIPA,CAPN2,AREL1,CHMP4C,RNF187,TRIM3,PSMD1,MAN1A2,CHMP5,RNF148,HECTD1,UFD1,KLHL22,CCDC47,RNF20,NQO1,ZNRF1,KLF1,COP1,CUL3 |
| 1.462e-11 | -24.95 | AQP6 (aquaporin 6) | protein interactions | 363 | 329 | 149 | 19454 | 5460 |
CMTM7,FDFT1,VAPB,SMCO4,TMEM115,SYNDIG1,MMP14,OTULINL,CCDC167,TMUB2,SEC22A,VAMP1,CTXN3,TOMM22,CLDN4,BET1,GOSR2,AGTRAP,STX7,TLCD1,RABAC1,EMP3,TMEM203,JAGN1,SLC38A1,FIS1,PLN,CYP4F22,SLC35E4,FAXDC2,TMEM100,SLCO3A1,CYB561,ZDHHC24,VEZT,EFNA5,THBD,TMEM229B,FAM177A1,CYB5R3,STX12,CYB5B,VAMP2,CTSA,SEC61G,IFNGR1,NEU1,PAEP,TOMM6,PLPP6,RAB18,SACM1L,TMEM60,SLC35G2,SLC39A7,C2CD2L,CD52,PDZK1IP1,SCAMP5,FXYD6,EMC6,SYNJ2BP,MARCHF5,PMP22,SLC38A7,TSPO2,TMEM97,SLC66A2,MFSD5,STX5,TMEM14A,TIMM23,USE1,GRM2,PLP2,SLC35F6,SEC22B,NINJ1,SLC7A1,TMEM167B,MFSD3,TMEM254,TMEM243,DERL1,TMX2,SLC39A9,ORMDL1,REEP6,ARL6IP6,HMOX2,SLC35B4,VAMP5,GJB2,TECR,SLC7A8,VKORC1L1,SFRP4,TMEM74,CYBC1,SYNGR1,SFXN2,CDIPT,VAMP3,PLP1,SLC35F1,TFRC,YIPF4,UBIAD1,NRM,INSIG2,SELENOK,SFT2D2,FKBP8,TMEM50A,ALOX5AP,DNAJC30,ADIPOQ,UNC50,ERG28,YIF1A,STX8,RUSF1,SFXN1,ADGRE2,BTN2A2,TMEM11,TMEM42,SLC35A1,TMEM107,CD81,SLC41A1,ORMDL3,TMEM144,TMEM199,TMEM19,SLC25A46,CNIH1,UBTD2,STX6,FUNDC2,AIG1,ANKRD46,VTI1B,SPPL3,CXCL9,FA2H,COX20,PTPN1,RPRM |
| 1.478e-11 | -24.94 | Ribosome | KEGG pathways | hsa03010 | 134 | 84 | 7161 | 2463 |
RPL3,RPL10A,RPL17,RPS17,RPS13,RPL10,RPL27A,RPS2,RPL23A,RPL37A,RPL19,RPS4X,MRPL16,RPL31,RPS9,RPL35A,RPS10,RPL10L,MRPL9,RPL29,RPL35,RPL23,RPS20,RPL26,MRPL20,RPS15,RPL26L1,RPS29,RPS24,RPL6,RPLP2,RPL18,MRPL11,RPL9,MRPL36,MRPL24,RPS5,RPS7,RPL32,FAU,MRPL18,RPL39,MRPS21,RSL24D1,RPL7A,RPS26,RPS28,MRPL12,MRPS17,RPL27,RPS12,MRPL10,RPL24,RPL22,RPL15,RPS11,MRPS16,MRPS11,MRPL22,MRPL34,RPS27L,RPSA,UBA52,MRPL13,MRPL23,RPS27A,MRPS7,MRPL17,MRPS9,MRPL33,RPS16,RPS14,RPLP1,RPS23,RPL7,RPL8,MRPS18C,RPL13A,RPL28,RPLP0,RPL12,MRPS18A,RPL4,RPS3 |
| 1.478e-11 | -24.94 | Ribosome | KEGG pathways | ko03010 | 134 | 84 | 7161 | 2463 |
MRPL36,RPL9,MRPL11,RPL18,RPLP2,RPS7,RPS5,MRPL24,RPS20,RPL23,RPL35,RPL10L,MRPL9,RPL29,RPS10,RPL35A,RPS24,RPL6,RPS29,RPL26L1,RPS15,MRPL20,RPL26,RPL19,RPS9,MRPL16,RPL31,RPS4X,RPL17,RPS17,RPS13,RPL10A,RPL3,RPL37A,RPS2,RPL23A,RPL27A,RPL10,RPL8,RPL7,RPS23,RPS14,RPLP1,RPS16,MRPL33,MRPL17,MRPS9,MRPS7,RPL4,MRPS18A,RPS3,RPL12,RPL28,RPLP0,RPL13A,MRPS18C,MRPL13,RPSA,UBA52,RPS27L,MRPL34,MRPL22,MRPS11,RPS27A,MRPL23,RPL24,RPL27,MRPL10,RPS12,MRPS17,MRPL12,RPS28,MRPS16,RPS11,RPL15,RPL22,MRPS21,RSL24D1,RPL39,MRPL18,FAU,RPL32,RPS26,RPL7A |
| 1.479e-11 | -24.94 | PPIA (peptidylprolyl isomerase A) | protein interactions | 5478 | 318 | 145 | 19454 | 5460 |
TRIM23,UBE2H,COL1A2,AKT1,CFL1,LDHA,NDN,RHOJ,SNX3,SH3BGRL,NR1I2,SRPK2,VIRMA,CCNF,ENO1,EIF4A3,TUBA1B,RPA2,METTL14,HEXIM1,UBE2M,PCK2,ATG16L1,CDC42,CFTR,CDK7,PIAS1,HSPA5,SOD1,RPA3,DDX46,RHOU,BAP1,RNF113A,SQSTM1,MAVS,TMOD2,GRSF1,DPP4,EMC4,HDAC6,COPS5,GAPDH,CDK9,ITK,UBE2N,ARL10,RB1,RAC2,TFCP2,ACTR2,SOD2,RAD23B,FBP1,PPIF,H2AX,TIMM8A,NEDD8,HUWE1,HSPE1,HNRNPK,MEPCE,RIGI,RPL23A,KLHL15,HSD17B10,RHOB,MYC,CUL3,LDHB,HNRNPC,AK3,BTF3,PDE4B,SAMHD1,CAPG,TAGLN2,EIF4A2,PSMD4,LGALS3,ACTB,JAK2,DLST,RAN,ACAA2,PPT1,PRSS23,ANXA7,PIH1D1,ZER1,PRR13,RND2,UFL1,GPC1,ARL6,DUSP9,PEBP1,HDAC5,TERT,RHOG,AGR2,PEDS1,POU5F1,PPP3CA,ARMC8,CRIP1,PRPF19,RAB5C,IFIH1,HNRNPA1,CTNNB1,DDRGK1,COPS7B,TCP1,RHOH,PPIA,CBFB,PHB1,IGBP1,S100A8,HEBP1,EZH2,PIR,RND3,ERRFI1,B3GNT2,MACO1,E2F4,ETFB,SUPT5H,SOX2,ISG15,EEF2,G3BP1,VDAC1,ETFA,TRIM37,FKBP2,CPLX1,SAR1B,BCL7B,HNRNPA2B1,PCNA,EWSR1,UBE3A |
| 1.479e-11 | -24.94 | ATP5PB (ATP synthase peripheral stalk-membrane subunit b) | protein interactions | 515 | 318 | 145 | 19454 | 5460 |
HSP90AA1,PMPCA,OPRM1,ACO2,FMC1,AUH,KDSR,MTG2,NDUFB7,PARL,ESR2,B4GALT3,ATP5F1B,ZMAT2,RETREG3,DKK3,MTG1,DLST,CCDC90B,CYB5R3,TACO1,VDAC2,LMBR1L,SLC25A3,CAV2,VAPB,ATP5PO,TIMM29,SLC19A2,TOMM22,WDR77,ASB3,G3BP2,CMAS,CERS6,NDUFS2,STK26,HADHA,ATP5IF1,TACR1,EXD2,PYM1,ARMC8,MED4,MRPS26,AGR2,FAM241B,RHOG,DDRGK1,BTF3L4,HNRNPA1,PTPN5,STOML2,MTRF1,HSP90AB1,OPRL1,EGLN3,PSD2,TTC9C,GATD3,FAM136A,PDHA1,DSTYK,UTP25,IMMP2L,ATP5F1D,VDAC1,CHCHD2,G3BP1,HINT2,NDUFA4,NDUFB5,HSPD1,STK24,ATP1B3,TUFM,ATP5F1A,HSPA14,VIRMA,SEC63,UQCRQ,ZNF622,PTPMT1,SCAMP2,MTRES1,HEXIM1,STOM,GPR35,CHMP1A,RPA2,P2RY12,COQ8B,CRYZ,BCL6,HSPA5,TOMM20,FBXW7,LPAR1,MRPL40,CERS2,KDM1A,GFM1,TCEA1,VIPR1,GRIA2,RETREG2,RPA3,DVL2,BRD3,RPS2,TMEM70,ESYT1,SPP1,P2RY1,ATP1B1,TPM3,CCR6,ATP5MG,COX5A,EI24,RELL1,TSPO,GRSF1,CMSS1,SLC25A12,LMAN1,ATP5PD,STARD3NL,SSBP1,AIFM1,COQ8A,GFM2,NDUFS3,ZMYM3,METTL15,AURKAIP1,MTCH2,MRPL11,ATP5PB,FASTKD5,VRK1,EMC2,ATP5PF,TCOF1,SFXN1 |
| 1.479e-11 | -24.94 | PSMC6 (proteasome 26S subunit, ATPase 6) | protein interactions | 5706 | 318 | 145 | 19454 | 5460 |
PML,DVL2,BAP1,SOD1,RPA3,SQSTM1,HSPA5,UBA52,PSMC4,UBLCP1,PAAF1,CFTR,NEK2,CDC42,METTL14,JKAMP,SDCBP,RPA2,ACACA,UBE2M,HEXIM1,PSMA6,CCNF,RPS12,MSN,UBE2I,GTF2A1,PSMC5,GANAB,SEC61A1,ADRM1,CHMP5,CPT2,VIRMA,PTPN11,PSMB2,AR,USP14,SPOP,UBE2H,ATP1A1,PSME1,HSD17B10,KPNA2,HUWE1,PSMA5,SEM1,EIF3E,FKBP8,MEPCE,VTA1,INSIG2,EEF1A1,PSMB9,TMEM31,ZFAND2A,RAD23B,PSMC3,AIFM1,PSMB1,FZR1,CDC5L,MDM2,EDEM1,TPM3,MFN1,ZFAND2B,COPS5,HDAC6,SEC14L5,PSMD7,CCDC92,PSMA3,HDAC5,CRY1,TXNL1,HSPA8,NSFL1C,STAU1,EYA3,UFL1,DDI1,PSMC1,PSMB3,EMC9,PSMB7,LMBR1L,S100A6,PRMT5,SIAH1,PSMD6,FBXO22,MATR3,PSMD4,ESR2,PSMB6,PSMA4,CDKN3,CUL3,MYC,CCDC85B,PSMD1,SMARCE1,PSMD14,BRCA1,CCT2,RIT1,ABCF1,PABPC1,MRPS11,UBE3A,EWSR1,RUVBL1,CDK20,KRAS,PSMA1,PSMA2,UFM1,RFC2,RPS27A,MCM6,PSMD12,ISG15,PPP2R1A,SOX2,CHMP4C,PLS3,EZH2,MOB3C,CRKL,POLR2C,PSMB5,PSMB4,PSME2,CCAR2,RPS10,HSP90AB1,EGLN3,PSMD3,PIK3R1,GSTM3,CTNNB1,ATG7,PSMD10,RB1CC1 |
| 1.503e-11 | -24.92 | PINK1 (PTEN induced kinase 1) | protein interactions | 65018 | 667 | 266 | 19454 | 5460 |
RPL24,H2AC4,KARS1,GAPDH,CD81,MIF,PLG,KCTD3,RPS16,ITGA6,SYNCRIP,AKR1B1,MCL1,KIF1C,RPSA,HNRNPK,CSE1L,TOLLIP,CDC40,H2BC14,RPL17,NAE1,MAP1B,PALM2AKAP2,DHX9,CLPB,ATP1A1,IGF2BP1,AKT1,TRIM32,ST13,CFL1,H2BC9,ADRM1,UQCRC2,RPS3,CALML5,KLK6,ZNF326,SAMM50,IDH2,H2BC11,ACACA,UBE2M,SPTBN1,HSPA5,TOMM20,IRF3,RPL27,PRDX6,DLAT,HNRNPH2,AGR2,FKBP4,H2BC17,RAB5C,GSTM3,YWHAG,PPIB,DYNC1I2,TCP1,HNRNPL,RAB1B,EIF2S1,CCT7,HSP90AB1,FUBP3,FABP5,PPFIA3,MAGED2,S100A8,PLS3,TUBB4B,RPL18,MTA2,RPS7,EEF2,TUBA1A,SERPINA3,H1-3,VDAC1,KRAS,IMPA2,RAB18,RPL28,CCT8,PABPC1,MYO1B,RBM27,PRSS1,MDH1,HNRNPC,LDHB,BAG3,PSMD1,HMGCS1,TRIM29,MATR3,RPL10,VDAC2,PRMT5,ACAA2,FDFT1,PIP4P2,NUFIP2,EIF4B,HSH2D,ZC3H14,RPL27A,TOMM22,PHB2,EEF1G,SPECC1L,DDX39B,LCN1,DDX5,SF3B1,HSPA8,ECD,POR,NME2,DNAJC7,KLHL9,H2AC14,CALR,MOV10,MSMO1,TOMM70,AIFM1,RPL12,SEC23A,SOCS4,SRP72,C1QC,CCT5,H2AJ,GGCT,MAP1LC3B,EEF1A1,TF,THRAP3,HUWE1,H2AC6,MSH6,GLUL,EHD4,PPP1R12A,NSDHL,H2AC25,HSD17B10,PC,RPL23A,PIP4K2C,CASC3,CA2,CTSD,NONO,GMPS,TUFM,FBXO7,ATP5F1A,TXN,RAB14,LDHA,RPL22,SLC25A31,EIF4A3,TUBA1B,CTTN,ENO1,MSN,PTEN,PIWIL3,ALB,GANAB,H2AC7,PICALM,HSP90B1,JUP,LMNA,RARS1,ARHGAP1,RPS14,PCK2,SF3A1,SMC4,EIF5B,FADS2,NCDN,SQSTM1,H2BC12,DROSHA,TRAF6,CSTA,BCL2L1,RB1CC1,HNRNPD,RAB3D,PSMD3,PRDX1,HNRNPA1,SPTAN1,RPL7,DHX15,ERLIN1,CACYBP,PPIA,PSMB5,RPL9,ATP6V1A,MAP1LC3A,NME1,RPN1,RPL29,CYB5R1,PPP2R1A,ACTN4,RBBP7,DHX16,SAR1B,FANCG,SRSF4,MCM6,HNRNPA2B1,SLC25A5,ZYX,HSPD1,SRSF7,BAG2,MYO6,YWHAZ,LMNB1,HTRA2,CBR3,HSP90AA1,DHRS1,NIBAN2,MCM3,MCM4,TOMM40,ACTB,SIAH1,RPL35,RBBP4,TUBB,AKR1C2,PRDX2,RPL19,PARL,RAN,ARF1,SARM1,SEC61B,RPS9,PI3,CRYAB,ARCN1,SLC25A3,RDH12,NSFL1C,HAND2,RADX,GDPD3,FTL,CDSN,HADHA |
| 1.523e-11 | -24.91 | EXD2 (exonuclease 3'-5' domain containing 2) | protein interactions | 55218 | 385 | 169 | 19454 | 5460 |
MTX2,TOMM22,NDUFAF3,MRPL12,RND2,ACAA2,UBAC2,ATP5PO,NDUFA5,AKAP1,RAB5A,HADHA,PHB2,NDUFS2,SLC31A1,MRPS7,ARMCX2,ZDHHC17,PXMP2,PYCR1,HNRNPAB,RAB11A,MRPL16,BRCA1,MRPS25,NOA1,RBBP8,HTRA2,FIS1,DLST,TACO1,LMBR1L,MRPL13,SYBU,RMDN3,RANBP6,ATP5F1B,MRPL23,ESR2,APEX1,GNB1,NDUFAF4,ETFB,HSDL2,FAF2,SOX2,RAB4A,PTRH2,NDUFS6,PDHA1,NUDT19,NDUFA12,BCKDK,HSPD1,PREPL,MRPS11,HINT2,ETFA,KGD4,TRIM26,USP30,KRAS,HNRNPDL,IMMP2L,MRPS17,RAB5C,MARCHF5,STOML2,MRPS35,SEC61A2,BABAM1,CLPX,DDRGK1,MRPL9,NDUFV2,RHOG,RPL23,PEX3,MRPS26,RAB35,FAHD1,HNRNPL,RAB11B,COX14,NDUFS8,EGLN3,COQ8B,MRPL10,CDC42,EIF2B3,MRPS34,QRSL1,PDCL,PML,GRAMD2B,DLAT,GFM1,MAVS,TWNK,MRPL41,MRPL40,YKT6,NME4,PDHB,POLDIP2,TOMM20,PYCR2,C9orf72,NDUFAF2,CSK,FBXO7,CISD1,MRPS16,ATP1A1,CCNF,CDIPT,MRPL53,ACAT1,SEC61A1,MRPS28,MGST3,MRPS21,NDUFA2,MRPL47,MTCH2,SNAP29,ATP5PB,METTL15,BCS1L,MTARC2,PPIF,NDUFS3,MRPL49,ATP5PF,SFXN1,EHD4,MRPL52,RAB13,MRPS18B,HSPE1,RAB3B,PDE12,MRPS33,FKBP8,RIGI,MRPS18C,FASTKD5,MRPL22,COX5A,SLC25A46,ATP5MG,GRSF1,MOV10,SLC2A1,ARL10,MGME1,COX4I1,ALYREF,STT3A,PTPN1,MRPS9,AIFM1,RAC2,MRPL50,MRPS23,MRPL24,ATP5PD,DBT,LMAN1 |
| 1.561e-11 | -24.88 | RRS1 (ribosome biogenesis regulator 1 homolog) | protein interactions | 23212 | 332 | 150 | 19454 | 5460 |
CFTR,RPS14,ZNF574,RPLP0,MACROH2A2,SDCBP,MRPS34,RPA2,MTDH,RNF113A,RPL27,RPA3,NLE1,SIRT7,PML,BRIX1,UTP23,NPM3,DGCR8,RPS15,RPL4,RPS17,PPP1CC,RPF2,CIAO1,RPL7A,IGF2BP1,UBE2H,MRPS16,CMA1,RC3H2,PRKRA,FGFBP1,RPS12,RPS20,RPS3,CCNF,EIF4A3,ZNF330,SRPK2,RPL13A,ACTR1A,RPL15,MRPL11,RPSA,CBX3,TFRC,RBM34,RPL23A,RPL3,DHX9,MRPL52,RPS13,RPL17,NOC4L,DPP4,MOV10,GRSF1,FAM20C,RPS2,CDK12,BRD3,RPL10A,MPHOSPH10,CHCHD1,SNRNP70,SRP14,MRPS9,KRR1,RPL32,CDK9,DKC1,ZBTB2,SURF6,RPS16,RPL35A,CGAS,RND2,SYK,APOBEC3C,ADNP,APPBP2,SF3B1,RPS28,MRPS7,STAU1,NOP53,ZNF668,MYC,HNRNPC,CUL3,RPS5,RPS26,H1-1,CDKL2,NSA2,RIT1,DNAJB6,FYTTD1,DCAF4,ZCRB1,FTSJ3,POLR3B,SF3B4,RPL37A,RPS9,FAU,SURF2,RPL19,ESR2,MATR3,SNRNP40,FBXO22,RPL35,RPL29,NCSTN,H1-3,RPS7,TOP3B,RAF1,E2F4,RPL18,RHOBTB1,GLE1,CHMP4C,GDI2,RPS24,RPL31,RPL28,SRSF4,RPS4X,KRAS,H1-6,DDRGK1,IFI16,MRPS35,RPL6,RPL23,DDX23,EED,RPLP2,RPLP1,HP1BP3,RPL9,RPL8,SRSF1,RPS10,NOP58,LYAR,RPL7 |
| 1.563e-11 | -24.88 | response to cytokine | biological process | GO:0034097 | 834 | 334 | 18204 | 5365 |
MIR142,ADIPOR2,PADI2,ZFAND6,PTP4A3,GPR17,IFNA10,IFNAR1,CDC42,BGLAP,DAPK1,SFRP1,TUBA1B,CREB1,IL6,TXNDC17,TRAF3IP2,TIMP3,CCL17,FCER1G,MX2,IL12B,UBE2K,AKAP12,IL2RB,TLR3,CCL5,FOXP1,CXCL9,DAPK3,VEGFC,IFNGR1,NFIL3,STX8,IRF3,IL6ST,OXSR1,MT1X,CSF2,HAX1,RPS6KA4,CNTFR,LILRB1,CD274,SRM,IL12A,INPP5K,MX1,HSPD1,CCL3,VPS26B,PRL,SELL,GPR35,HSP90AB1,CDC42EP4,ZYX,MAVS,MIR204,IFNB1,IFI27,CAV1,PAX6,SIN3A,SOCS3,EEF1E1,LILRB4,CXCL3,FABP4,MIR146A,IFNA2,CD4,CLDN1,MIR324,LILRA2,MIR149,AQP4,MIR31,MCL1,JAK1,BRCA1,IL4,MYD88,MIR342,SYNCRIP,MYBL2,HSPA5,ILDR1,SOCS5,IL20RB,HTRA2,TNFRSF1B,IFIH1,IFNK,PCK2,PLCB1,IL18BP,IL2RG,JAGN1,OXTR,CXCL11,CCL24,MT3,CTSK,HYAL2,AANAT,NPR2,ATP5F1B,SLC1A1,GH1,MIR370,IL1A,PDCD10,NFKBIA,TANK,SMAD4,SRSF7,TNFSF18,CCL20,CXCL1,CCR7,MAT2A,STAT6,ISG15,CCR6,IFNA13,SPP1,IL1B,DHX9,AKT1,COL3A1,UBE2G2,CXCR6,GCLC,TUBA1A,OAS1,UGCG,BAD,KRT8,GSK3A,IRF8,CCR1,MRC1,SYNGR1,FOSL2,ACTN4,STAT1,ACP5,BST2,JAK2,IRF7,STXBP1,PHC1,IL5,BCL2L1,CRKL,IGBP1,IL2,TRIM63,PID1,CBL,STAT2,KIT,SOX9,CCR5,EIF2AK2,CD14,FAS,TOLLIP,EIF4A2,CCL21,XBP1,CDC42EP2,IL1R2,RPL13A,IL13,MIR34A,CAMP,LEPR,AZI2,SNX10,IFNG,TP53,ICAM1,RRAGA,CD47,CXCL8,IL17F,FASLG,LEP,TLR4,EPS8,TRIM21,CCL8,PTPN11,CD58,CCL11,KLF4,SMARCA5,LILRA3,GHR,SRC,COMT,TIMP4,IL18,KCNJ11,EXT1,ACKR3,IL3,IL7,TIMP1,NFYB,LILRA1,ALPL,MKKS,FGF23,IKBKB,IL34,EGR1,CHCHD4,CYP27B1,MIR455,GAPDH,IL15,EPO,NFE2L2,PDE1B,MIR493,ACTR2,CAPN2,FZD4,IFI16,CXCL13,CCL1,OSM,IRAK4,IRF1,PIK3R1,HELLS,TRIM6,EDA2R,RPS3,PHB1,DUSP1,BIRC2,TFRC,LAMP3,PDIA3,PDE12,CX3CR1,TRAF2,CRHBP,TAF9,TRAF1,TRIM32,XCL1,RAF1,CX3CL1,MIR101-1,ZC3H15,SHMT1,ADIPOQ,TNF,CCR3,PLP2,IL1RAP,ADIPOR1,PYCARD,CXCR4,NKX3-1,CD40,RPL3,CCL23,CXCR1,CXCL12,CCR4,MME,SYK,CH25H,SLC25A5,GREM2,CITED1,NUP35,GPR75,CCL4L1,MRAS,TYMS,KCNJ8,PIGA,WBP1L,CACNB4,NFKB1,ILK,B3GNT2,CCL18,IL15RA,PDE2A,PML,CDK9,TMSB4X,LRAT,CCL2,CHI3L1,FOS,HCLS1,IL2RA,CXCL10,TNFRSF14,MAPKAPK3,CDK4,STAT5A,CSNK2B,XRCC5,PLSCR1,TBK1,TIFA,CCR2,CCL19,VAMP3,AIF1,MT2A,INA,CACYBP,RAD23B,CYP1B1,SLC12A2,TRAF6,RPS16,CCL25,XAF1,TLR2,CXCR3,CD38,PRKCA |
| 1.580e-11 | -24.87 | RPL23A (ribosomal protein L23a) | protein interactions | 6147 | 552 | 227 | 19454 | 5460 |
CAVIN2,RPL10,CMTR1,ZNF189,MRPL13,ATG3,H1-10,FTSJ3,MRPS25,NSA2,RPS26,ICAM1,SFN,MYC,BTF3,STAU1,UFL1,MRPS7,PACSIN3,HERC3,RPS28,SF3B1,PPT1,MRPS18A,PIH1D1,NUFIP2,EIF4B,RPL27A,MTF1,LYAR,RPS10,EED,AGR2,DRG1,RPL6,WWP2,DDRGK1,CTNNB1,XPO1,MRPL9,KRAS,RPL28,RPS4X,RPL31,RPL18,RPS23,SLC1A2,TRMT1L,RPS7,ISG15,RPL10L,RSL24D1,SRPK2,PPP1R10,RPS3,PSPC1,RC3H2,UBE2H,ELAVL2,RPL7A,ZSCAN25,RPS17,H2BC9,RPS15,PML,RPL27,BAP1,GFM1,RNF113A,SSR1,RPA2,ZNF770,TFB1M,TFIP11,HEXIM1,CFTR,RPS27L,FZR1,CAND1,RPS16,CDC5L,SURF6,TMPO,RBM42,DKC1,RPL32,SYNCRIP,SNRNP70,RPL24,USP15,RPL10A,RPS2,CMSS1,ENY2,CD81,COPS5,PPIL4,MRPS33,NEDD8,RPL17,MEPCE,MRPL52,SNIP1,RPL3,RBM34,DNAJC2,TFCP2,DDX42,IPO8,TP53,RPSA,UBL4A,H2AX,RPF1,RPL35,RPL7L1,MRPL23,RPL19,FAU,RPS9,SEC61B,RPL37A,ZCRB1,BRCA1,RIT1,RPS5,HSP90AA1,CUL2,NOP16,CUL3,ACO2,ZNF668,MRPL16,NOP53,GPC1,MRPL57,G3BP2,CCDC86,JADE1,EMC9,WDR77,H1-5,RPL7,PPIA,PHB1,MRTO4,RPL9,FOLR1,RPL8,RPLP2,RPLP1,MRPL18,RPL23,RSBN1L,MRPS26,MRPS35,NDC80,EIF3D,ATG7,TRIM37,RAD21,RPS27A,TRIP4,SLC25A5,RPS24,FAM76B,RPN1,EZH2,RPS11,B3GNT2,RPL29,RPL13A,NDN,RPL22,METAP2,CTTN,CCNF,RPS12,PTEN,RPS20,PRKRA,NONO,TUFM,PPP1CC,HMGB1,RPL4,FBXW7,DGCR8,MRPL17,NPM3,NF2,BRIX1,PIAS1,SIRT7,RPA3,RPL26L1,RPLP0,TPT1,EEF1E1,RPS14,CDK7,TOP1,DCUN1D1,RPL35A,NOP9,CDK9,MDM2,KRR1,RCHY1,RPL12,MPHOSPH10,EMC4,GRSF1,HDAC6,NOC4L,VRK1,PAK1IP1,RPS13,MRPS18C,NKRF,SRP72,ILF2,FBP1,FNTB,RPL15,TAF1D,EEF1A1 |
| 1.585e-11 | -24.87 | AR (androgen receptor) | protein interactions | 367 | 983 | 370 | 19454 | 5460 |
ADNP,VAV2,MED23,MYL6,WDR77,PPP1CB,MLH3,TGFB1I1,STAP1,PSMC1,NUBP2,LMNB1,WDR20,MYO6,SP1,CUL2,MCM3,RNF40,GNB1,RAN,CPSF1,EZH2,RBPJ,E2F4,TXNRD1,TPD52,FEN1,G3BP1,PPWD1,TRIP4,UBE3A,DDX23,RPL23,DPY30,UBXN6,TAF7,PRPF19,PSMD3,CCAR2,PHB1,MYEF2,COPS2,TSG101,XPO5,JUP,CDK1,CCND1,MYL12B,MYLIP,CPSF4,PSMC4,HMGB1,SGF29,GTF2I,AATF,FADS2,MME,SQSTM1,TADA3,XPOT,NAPA,SEC13,GMPS,USP14,AR,NONO,ATP5F1A,RUNX1,SLC25A4,YES1,LDHA,STUB1,PELP1,TRIM24,PTEN,UBE2I,RTRAF,GSK3A,DMAP1,ILF2,MTA3,SMAD1,SOCS3,ING1,CTDSP2,TOM1,THRAP3,MDC1,PRDX4,RPS13,RNF20,GLUL,PSMD7,MED21,FGR,DNAJC7,TLE1,RNF14,NFKB1,CALR,CAV1,RCHY1,PLAA,CTBP1,HSH2D,SSBP2,RPL27A,ZNF362,HNRNPA0,RNF41,SAP18,XRCC5,HIRA,EP300,HSPA8,APPBP2,RBM27,MLF2,BRMS1,LDB1,PSMD6,ATP5F1B,MORC4,PPP5C,PHF12,ZHX3,GTF2F1,PHF21A,GTF2F2,PPIL3,VDAC1,ZNF609,PAX6,RERE,TOP2B,PABPC1,RTCB,RUVBL2,FKBP4,FOSL2,HSPB1,SHC3,TCP1,EIF2S1,NKX3-1,SRSF1,RFX5,EED,ZNF326,RPRD1B,TRIM68,HEXIM1,SUMO1,CCNH,GTF3C4,KDM1A,HSPA5,HSPB2,HNRNPH2,NR0B1,SPOP,MED22,PTPN11,SRC,CSTF3,ZBTB33,PSMA6,LIG3,RPS3,CREB1,GTF2H2,ING2,QSER1,PSMC5,IK,NEFL,CHAMP1,RNF8,PSMC3,GRAP2,TAB2,RAP1A,ZMYM4,KPNA2,TOLLIP,CAPZA1,RPL3,BECN1,SMAD4,RBM17,KARS1,TSEN34,CSNK2A1,RPS16,CDC5L,IRF2BPL,ACTL6A,NDE1,TXNL1,BRCA1,YWHAZ,MED10,SETD7,HSP90AA1,RPS5,PIK3R3,SMARCE1,MED17,ACTB,USP5,RPS9,PRKAG1,PPID,SART3,RPS11,RAF1,RBM12,JUN,FAF2,ACTN4,ZBTB16,SSRP1,FLOT1,FOXP4,FANCG,AHCYL1,PSMD12,HSPD1,SLC25A5,NEK9,HNRNPD,HAX1,MED4,PIK3R1,SIAH2,BCL7C,DHX15,PSMB4,PSMB5,ATP6V1A,KRT8,HNRNPH3,CDK7,PIK3R2,MEF2A,PIAS1,INPPL1,TCEA1,CDC73,TMOD3,VIRMA,UBB,SCML2,ENO1,CTNNA1,CMBL,ACTR2,GBE1,H2AJ,FARSA,HUWE1,PTGES3,RNASEL,PAGR1,CACUL1,BRD3,CLP1,FOXP1,SPATS2L,GRSF1,ERCC3,MDM2,CDK9,SMAD3,RB1,PSMB1,CSNK1A1,CNDP2,PSMB3,SYK,TOM1L2,IL6ST,PHB2,MED13L,DDX5,SF3B1,PSMD14,CKB,PNRC1,HNRNPAB,CREBBP,PSMD1,KANSL3,TAX1BP1,MATR3,CBX5,MIDEAS,ATXN1L,ZMYM2,SMU1,RPS23,SMARCB1,EEF2,RPS7,RUVBL1,PSMA2,HNRNPF,PSMA1,PAK6,RPS4X,CCAR1,BCL7B,BCL9,MYO1B,DDX1,POU5F1,IFI16,CTNNB1,XPO1,DNTTIP1,SUMO2,HNRNPL,HSP90AB1,FUBP3,SIN3A,SH2D1A,HPS6,KLF4,LUC7L3,SUPT7L,HDAC3,BCL6,BAP1,DDX46,PGK1,PSMB2,AKT1,TRIM32,SMARCA5,SUGP1,DAPK3,IDE,PSPC1,INTS12,MACROH2A1,CSNK2B,CAPZA2,DDX42,CDK8,GNAI3,TP53,CSE1L,MEPCE,ZNF451,DHX9,SMCHD1,RPL24,SHC1,MED27,USP2,GAPDH,TPM3,CAND1,FZR1,KLK3,ESD,MRPS9,MTAP,GATAD1,CDK6 |
| 1.585e-11 | -24.87 | TXN (thioredoxin) | protein interactions | 7295 | 321 | 146 | 19454 | 5460 |
PGAM1,NFKB1,GAPDH,COPS5,GPRASP2,CRBN,DNAJC7,SYNCRIP,AIFM1,SSBP1,DCUN1D1,CAND1,MBD5,TP53,FBP1,RRM1,UBL4A,UBE2V1,GLRX5,MAP1LC3B,HADH,TFCP2,MSRB3,RNF8,SFXN1,TCOF1,MYD88,RAB1A,TAGLN3,HINT1,MRFAP1,HSPE1,EIF4EBP2,MEPCE,OLA1,PPP1CC,USP14,MTPN,TXNIP,RC3H2,LGALS8,CHCHD4,EIF3G,GLOD4,NIF3L1,FXN,UBE2H,SERTAD3,ENO1,CCNF,PTEN,TXNDC12,RAB14,HPF1,GPX1,SRPK2,VIRMA,WDR5B,AKR7A2,DDIT4L,GABARAPL2,CFTR,METTL14,GRM2,WWP1,LMNA,CDK1,RPA2,LUC7L3,WTAP,UBE2M,GSTP1,HEXIM1,BAP1,SOD1,RNF113A,NUCKS1,UBE2K,HSPA5,TAX1BP3,PRDX1,DDRGK1,CTNNB1,AGR2,AK2,GSTO1,POU5F1,TYMS,HSP90AB1,EGLN3,B3GNT2,UBL5,EEF2,SPG21,ACTN4,CCS,TRAF2,NUDT19,HSPD1,EWSR1,VDAC1,G3BP1,KRAS,TNF,GUK1,IMPA2,AHCYL1,NFE2,HNRNPDL,MX2,FKBP2,CUL2,CUL3,MYC,USP13,AK3,BTF3,PSMD14,DCAF4,SERPINH1,SETD7,RIT1,COP1,ENO2,SMU1,SIAH1,LGALS3,TAGLN2,PRDX2,APEX1,ESR2,MAT2B,NUP62,CDKN1A,DET1,PRDX3,PIH1D1,ARCN1,FKBP1A,GSTO2,CD40,PTRHD1,CRY1,COX17,UFL1,RNF11 |
| 1.623e-11 | -24.84 | RAN | smart domains | SM00176 | 85 | 52 | 9717 | 2575 |
RAB32,RAB19,RAB3C,RAB28,RASD1,RAB35,RAP1B,RAB11B,DNAJC27,RAB8B,RAB3B,RHOG,RAB5A,RAB9A,RAB37,RALB,RAB3A,RIT1,RRAS2,RAB6B,RAB14,RIT2,RAB29,RAB4A,RAB27A,RAC2,RABL2B,RAB5C,RAP1A,RAB22A,RAB33A,RAB6A,RAB3D,RAB9B,MRAS,RAB39B,RAB1A,RAB13,RHOU,RAN,KRAS,RAB11A,RAB23,RAB1B,RAB33B,RAB18,RAB30,RAP2A,RAB40AL,RAB31,RALA,RAB2A |
| 1.651e-11 | -24.83 | DDX1 (DEAD-box helicase 1) | protein interactions | 1653 | 425 | 183 | 19454 | 5460 |
FUBP3,MIR214,FAM98A,EIF2S1,DYNC1I2,SUMO2,MIR9-1,CHMP2A,IFI16,MIR143,WWP2,XPO1,YWHAG,YWHAH,MIR29C,DDRGK1,CTNNB1,MIR31,AGR2,MIR221,MIR140,MIR9-2,ABCF1,LSM14A,EWSR1,MIR206,TRIM11,RTCB,KRAS,MIR155,HNRNPDL,ISG15,SOX2,MIR222,PLS3,MOB3C,LMBR1L,MIRLET7B,MATR3,RPL10,MYC,GFUS,BTF3,BAG3,RFC4,HDAC5,HSPA8,DDX5,EP300,YAF2,FXR2,UFL1,STAU1,SYK,FBXO42,NEK7,PPT1,NUFIP2,EIF4B,PIH1D1,CSNK1A1,TMED9,RPS16,CAND1,MIRLET7G,TMPO,MIR429,LMAN1,COPS5,SNRNP70,H2AC4,MAP1B,MIR200A,ABCE1,DHX9,MIR9-3,NEDD8,HNRNPK,MIRLET7C,MIR16-2,TP53,DISC1,NUPR1,PSPC1,GRPEL2,IDE,FGFR1OP2,SPOP,RC3H2,IGF2BP1,UBE2H,RPL27,BAP1,MIR10B,THUMPD1,MAPKAPK3,NBN,HNRNPH2,LSM12,MIR107,MIR29A,MIR34B,PPP1R8,MAEL,CFTR,RPA2,EIF2B3,MIR21,DYRK2,HEXIM1,KLF4,MIR7-1,MIR7-2,PHB1,MIR141,NUP35,DHX15,HNRNPA1,MIR1-1,HNRNPD,TRIP4,HNRNPA2B1,G3BP1,RFC2,B3GNT2,EZH2,EIF3K,MIRLET7D,CUL2,CUL3,MIR98,BRCA1,MIR363,RIT1,PSMA3,ZFP64,PYGB,MIR106A,LARP4B,WDCP,MIR106B,RCHY1,DLGAP4,MIR25,DCUN1D1,EIF2B2,DBT,HDAC6,MIR34A,HUWE1,FBP1,MIR15A,MIR200C,EEF1A1,MIR20A,MIR17,ILF2,MIR16-1,CCNF,RTRAF,PTEN,UBE2I,NDN,FERMT2,VIRMA,RUNX1,AR,MIR145,RPA3,MIR205,MIRLET7I,MIR34C,MIR7-3,FBXW7,SAP30BP,ATG16L1,MIR1-2,COMMD3,METTL14,PICALM,GRM2,OXSR1,RPL26L1 |
| 1.665e-11 | -24.82 | RPS28 (ribosomal protein S28) | protein interactions | 6234 | 272 | 128 | 19454 | 5460 |
FBXO22,RPL35,TAX1BP1,ESR2,RPL19,FAU,SEC61B,RPS9,RPL37A,FBXW11,MDH1,COP1,RPS5,ICAM1,RPS26,CUL3,MYC,RPS29,PSMD1,EEF1G,G3BP2,RPS28,PYM1,EMC9,ADSS2,CSNK1A1,PIH1D1,FGF17,H1-5,WDR77,RPL7,RPS10,PHB1,FOLR1,RPL9,RPLP2,EED,DRG1,RPL23,HNRNPD,WWP2,RPL6,PSMD3,EIF3D,CTNNB1,TRIM37,KRAS,G3BP1,EIF2D,PFDN1,RPS4X,THNSL1,HNRNPA2B1,PABPC1,SLC25A5,RPL31,RPS24,CHMP4C,EZH2,RPL18,RPS23,RPS11,B3GNT2,RPS7,RPL10L,COPE,VIRMA,SH3BGRL,METAP2,RPS3,MRPL53,CCNF,RPS12,TRIM24,RPS20,MRPS28,TRIM23,RC3H2,UBE2H,PTPN11,RPL7A,PPP1CC,MTPN,RPS17,HMGB1,RPL4,RPS15,HSPA5,UTP23,CSTB,BAP1,RNF113A,HEXIM1,RPS14,RBFOX2,ATG16L1,FGF13,RPS27L,FZR1,RPS16,CAND1,RBM42,ARL10,RPL12,RPL24,SNRNP70,RPL10A,RPS2,ENY2,CD81,CSNK2A1,HDAC6,EIF3E,RPL17,RPS13,MEPCE,PQBP1,RPL23A,DNAJC2,TFCP2,SRP72,RPSA,UBL4A,EXOSC8,RPL15,H2AX,MAP2K3,MAP1LC3B |
| 1.725e-11 | -24.78 | negative regulation of protein metabolic process | biological process | GO:0051248 | 893 | 354 | 18204 | 5365 |
DDRGK1,CAMK2N1,TNF,ADIPOQ,SHMT1,RAF1,IL10,ROCK2,MIR145,PPP1R1B,RPS3,PHB1,MIR495,CORO1C,HMG20A,DNAJC10,HFE,VPS28,PFDN5,CDK5,RGS2,HEXIM2,MIR98,TBC1D24,MIR361,PYCARD,PKIA,DUSP10,LSM14A,CDKN1A,TYMS,ADNP,RB1,MIR17,MIR214,YWHAB,EIF4E2,AZIN2,PAIP2B,F2,ACOT8,PFDN1,MIR133B,MDM2,TAF7,SVBP,FKBP8,TP53,MIR1-1,MIR34A,FHIT,ITGAV,MIR26B,PTPRQ,TIMP4,BAG2,PTPN1,ZBED3,ENC1,KLF4,MIR147A,MIR590,TRIM27,IFI6,RNF139,LGALS3,CLN8,MIR28,SERPINA3,IKBKB,GAPDH,TRIM44,IFRD2,CHRNA7,GABARAPL2,BTG2,TSPO,NQO1,IMPACT,CDKN1B,SESN2,MIR106A,MIR711,SUFU,UFL1,MIR212,MIR503,PPARG,PAQR3,SGTA,RPL23,DBNDD1,DPEP1,SVIP,MIR346,CHP1,DUSP3,MIR144,SPRED2,MIR9-1,NCK1,GCLC,TM4SF20,PTPN22,DKK1,SPOCK1,MIR152,ISG15,TPPP,C9orf72,MIR200C,PFDN2,ATP2B4,USP14,MAD2L1,EIF4EBP2,FKBP1A,MIR29C,MIR339,MACROH2A1,AZIN1,IL1R2,CSNK2A1,CPEB1,CIRBP,MIR20A,RGN,CBL,CSTA,CSTB,IGBP1,MIR106B,CST3,SPON1,ITM2A,EPHA4,TIMP3,MIR126,FLCN,SFRP1,RTRAF,PPIA,DAPK1,DUSP19,AGO1,HSPB1,CRYAB,MIF,MIR132,INPP5K,SOCS4,CTDSP2,RNF34,PARD6A,CAV1,PFDN6,SOCS3,USP8,FURIN,FKBP1B,CDKN2D,SWAP70,HSP90AB1,AGAP2,CAV3,USP5,MIR208A,OPHN1,PKIG,SOCS5,CNKSR3,SNX3,SERPINB6,MIR31,SERPINB10,SNRNP70,IGFBP3,HBEGF,ARPP19,LILRB4,MTM1,PSEN1,MIR146A,SMAD3,MIR101-1,MIR24-1,ATRAID,DUSP22,TAF9,TNRC6C,EIF4A3,SERPINB1,LAMP3,DUSP1,MIR205,CLU,MINAR1,HDAC6,PRR5L,RPS7,STK38,CCAR2,MALSU1,IGF2BP1,DUSP6,PML,DNAJC1,HINT2,DCUN1D3,EIF2S1,TESK1,PIH1D1,NFKB1,MIR16-1,P3H1,MIR181D,MRPL13,GSKIP,GADD45A,G6PD,CAMK2N2,TRIB1,MIR378A,SPOPL,IFNG,SERPINB11,PDCD4,ROCK1,MIR135B,MIR15A,SERPINI1,SRC,SERPINH1,ANGPT1,MIR148B,HEXIM1,ATF4,THY1,MIR939,TRIM21,SQSTM1,PRMT6,MIR137,EIF3E,MIR455,MIR298,MIR181C,IVNS1ABP,MIRLET7I,CTSA,VEGFA,CEP85,MIR29A,NF2,TIMP1,UBASH3B,MIR874,MIR100,TRIM3,ITM2B,IFI16,MIR218-1,NTRK3,NTRK2,BEX3,RGP1,MIR153-1,EIF4EBP3,IGF1,SPRED1,SIRT7,CALR,CRTAP,TNFAIP3,CTNNB1,HYAL2,GSTP1,BAK1,INPP5E,MIR877,GPX1,MIR345,MIR1271,MIR182,NOP53,AKT1,SERPIND1,IL1B,SIAH2,SMAD4,TSG101,PTEN,PKIB,MIR125A,NR1H2,LRP6,CDK5RAP3,PPP1R8,PRKCE,CRY1,DEFB114,MIR448,DEDD,MIR10B,RPL13A,AATF,PFDN4,SNX12,EIF2AK2,PID1,PAIP2,CTDSP1,CAAP1,IL2,PLAA,MIRLET7B,PAK2,MIR221,SLC8A1,CRKL,YWHAG,BAX,EIF4E,MIR379,USP38,SERPINA1,GNAQ,MMP9,MIR107,CAMLG,MIR186,LDLR,ERRFI1,PRNP,SNTA1,SPRY1,DAPK3,SERPINA5,MAD2L2,PAX6,MIR204,SERPINB9,MIR210,RTN4,MIR148A,SYNCRIP,TIA1,UBE2B,DNAJB6,SFN,AQP11,MIR96,MIR21,DNAJC3 |
| 1.748e-11 | -24.77 | PEBP1 (phosphatidylethanolamine binding protein 1) | protein interactions | 5037 | 256 | 122 | 19454 | 5460 |
JAK1,PICK1,COA4,ARGLU1,RPS27A,PRPS1,RAB18,ANP32B,SOX2,ISG15,RAF1,ANP32A,EZH2,PIR,GDI2,KDELR1,IGBP1,PTK7,NKX3-1,PPIA,CACYBP,NUP35,SUMO2,PPIB,MAP3K14,HMGA1,PRDX1,PDIA3,TST,NQO1,HSPB1,YWHAB,IKBKB,PPM1B,TRAF6,AGR2,ATP5IF1,COX17,PMAIP1,EP300,DDX39B,PEBP1,COIL,UCHL3,NSFL1C,PRDX3,CD59,RAB6A,FKBP1A,MAP2K1,RMDN3,S100A6,DLST,CYB5R3,LGALS3,BAG3,TMED5,PYCR1,TMED4,SFN,SERPINH1,CKB,LAMTOR1,MED10,S100A11,ABCE1,NSDHL,RIGI,SLC25A32,TMEM33,HSPE1,TMSB10,WBP11,MLLT11,SOD2,GNPDA2,MCL1,UBE2N,CD151,MIF,COPS5,LYPLAL1,TPM3,MOV10,CALR,LAMTOR2,PGAM1,PMM2,POR,PGK1,PRKCB,SPCS2,SQSTM1,SOD1,RPA3,BAP1,YKT6,STK38,CDC42,SPR,DCTD,SCLT1,UBE2M,PRKCA,JUP,RPA2,GOLGA5,TRIM24,CCNF,RPP25,TXNDC12,CFL1,MAT2A,AKT1,EPHA2,NRP1,ATP1A1,UBE2H,MAPRE1,ATP1B3,IVNS1ABP,BICD2 |
| 1.812e-11 | -24.73 | SEC61B (SEC61 translocon subunit beta) | protein interactions | 10952 | 755 | 295 | 19454 | 5460 |
VLDLR,DNAJC3,ATP5MK,G3BP2,ARL6,MLH3,NPTN,ATAD1,NOTCH2,PGRMC1,TOR1AIP2,FKBP10,SLC25A3,ARCN1,VAPB,MED23,RMDN3,SEC61B,RPS9,GPR89A,ARF1,FAU,EIF3K,CYB5R3,CHCHD3,ABHD12,CHP1,RPL19,GNB1,RANBP6,IP6K1,RPL35,REEP4,GGH,VEZT,RAB11A,SCFD1,RPS5,VMP1,FAS,LMNB1,SLC39A7,ERP29,SCD5,RPS24,SLC25A5,SAR1B,RETREG1,EMC8,SEMA4C,PLEKHA8,FAF2,RPL29,NUP153,ERLIN2,ARFGAP1,RAF1,MACO1,RPS11,CYB5B,PLD3,STIM1,RPN1,RPLP1,RPLP2,CYB5A,RPL8,RPL9,PHB1,SLMAP,EGLN3,WDR44,RAB11B,NUP35,RPL7,PDIA3,C2CD2L,RPL23,CDK5RAP3,SPCS2,MTDH,RTN4,RPA3,FADS2,TMEM209,CERS2,YKT6,RPL4,FBXW7,ST7,ATG16L1,RABL3,RPS14,UBA52,SEC22B,ARHGAP1,RPLP0,RPL26L1,PDCL,P3H1,LMNA,HSP90B1,TMX4,SLC12A2,GANAB,RPS20,ODR4,RPS12,GXYLT1,VAMP3,SELENOT,CCNF,VKORC1L1,SEC63,RPL22,ZNF622,COPE,RPL13A,ARMC6,HMOX2,CTSD,LRP6,NRP1,ARFGAP3,SAYSD1,GNG5,RPL23A,TMX3,EMC2,STX8,NSDHL,RPS13,PRDX4,LBR,RPL15,CCDC47,FAM13B,ILF2,SRP72,FAM169A,DAP,HSPA13,CDCA3,CHID1,RPL12,PTPN1,SRPRA,EHBP1,HM13,EI24,CALR,TMEM199,OSBPL8,PPIC,POR,ESYT1,P4HA2,BMPR1A,RPS28,UFL1,EMC1,SSR3,CNPY3,SEC62,RPL27A,BET1,GOSR2,FDFT1,GGT7,RPL10,ESR2,ATP6AP2,RPL39,TMEM38B,RPS26,SERPINH1,ZMPSTE24,LAMTOR1,SPCS3,H1-10,PDIA6,RPL31,RINT1,RPS4X,RPL28,RAB18,KRAS,NUP42,DNAJC25,CCDC134,EEF2,RPS7,STBD1,SUPT5H,SMARCB1,TAPT1,RPS23,RPL18,GLE1,PTRH2,SEC61G,STX5,SPINT2,PTK7,TRAM2,COCH,RAB1B,RPS10,PPIB,XPO1,TENM3,DDRGK1,DDX50,RPL6,WWP2,RAB5C,SEC61A2,PTDSS1,DRG1,BPNT2,DERL1,RAB9A,RPL27,APMAP,TEX264,RAB29,HSPA5,RPS15,TRAM1,LEMD3,RPA2,USE1,SSR1,SEC61A1,CSNK2B,SRP54,SGTA,RPS3,ATL1,DHRS13,RPS17,EXOC5,GORASP2,RAB2A,NDUFAF2,RPL7A,KCNQ5,IGF2BP1,ATP1A1,CALU,DNAJC10,RPL3,ERO1A,STX18,YIF1A,DHX9,BCAP29,ATP2B4,SLC6A8,FKBP8,RPL17,RDH11,NUP107,SRPRB,UBL4A,SNAP29,PREB,RPSA,SELENOF,TFRC,SURF4,AGER,XXYLT1,STT3A,RPL32,CAMLG,LMAN1,TMPO,SLC38A2,RPS16,TMED9,ARL6IP5,DNAJC1,FZR1,RPS27L,CSNK2A1,COPS5,SELENOS,EDEM1,DHRS7,RPS2,RPL10A,AGPAT1,SMIM12,RPL24 |
| 1.860e-11 | -24.71 | RPS19 (ribosomal protein S19) | protein interactions | 6223 | 591 | 240 | 19454 | 5460 |
FGF13,CFTR,RPA2,KLF4,HEXIM1,RPL27,BAP1,RNF113A,RPS15,HSPA5,RPL7A,SUGP1,SMARCA5,ZSCAN25,RPS17,RC3H2,ATP1B3,MECP2,SPOP,UBE2H,PSPC1,RPS3,MACROH2A1,EIF2S2,MRPS28,RPL10L,SRPK2,SMURF1,PPP1R10,TP53,RPSA,UBL4A,IMP3,DNAJC2,TFCP2,DDX42,TAF2,MAP1B,RPL3,IMP4,RPL17,MEPCE,RBM17,CMSS1,ENY2,COPS5,CSNK2A1,CD81,PPIL4,RPL24,SNRNP70,SHC1,USP15,RPL10A,RPS2,NOL12,KPNA1,CD4,FZR1,CAND1,RPS16,SURF6,RBM42,DKC1,RPL27A,MTF1,PPT1,PIH1D1,NUFIP2,EIF4B,RPS28,PYM1,YAF2,HSPA8,SF3B1,EEF1G,STAU1,UFL1,HNRNPC,SFN,MYC,BTF3,H1-10,FTSJ3,H1-1,NSA2,RCL1,ICAM1,RPS26,CMTR1,VDAC2,GTF2F1,SF3B4,TRIM29,RPL10,RPS7,SPG21,EEF2,H1-3,SOX2,GLE1,TUBB4B,RPL18,RPS23,RPL31,EWSR1,RABGGTB,H1-6,KRAS,RPL28,RPS4X,WWP2,RPL6,DDX50,BAZ1B,DDRGK1,NT5C2,NGDN,CPEB1,DRG1,CBL,POU5F1,SRSF1,RBM5,RFX5,WDR82,LYAR,SNRPA1,RPS10,UBA52,RPS14,TOX4,JUP,ZNF574,RPL26L1,RPLP0,SIRT7,PRPF4,INPPL1,RPA3,SQSTM1,FBXW7,HMGB1,RPL4,UTP23,AATF,NONO,PPP1CC,RPL26,CTTN,TUBA1B,METAP2,MRPL53,CCNF,RPS12,RPS20,GSK3A,RPL13A,RPL22,VIRMA,FBP1,RPL15,EEF1A1,SRP72,NKRF,PPP1R12A,RPL23A,HAPSTR1,THRAP3,NOC4L,VRK1,HUWE1,PAK1IP1,EIF3E,RPS13,SPATS2L,MOV10,ATP1B1,HDAC6,MPHOSPH10,KRR1,RCHY1,RPL12,TOP1,RPL35A,CDK9,AKAP17A,H1-5,EMC9,MFAP1,HADHA,YTHDF1,NOP53,ARL6,G3BP2,STX7,NOP16,CUL3,RPS29,PRPF31,ZNF668,ZCRB1,BRCA1,RIT1,SP1,RPS5,ZNF22,FAU,SEC61B,RPS9,RPL37A,RPL35,RPF1,RPL19,B3GNT2,PPP2R1A,CHMP4C,EZH2,RPS11,HNRNPA2B1,SLC25A5,SRSF8,RPS24,FAM76B,TRIM37,G3BP1,TNF,RAD21,SRSF4,RPS27A,NDC80,NQO1,RPL23,PHB1,RPL9,RPL8,RPLP2,RPLP1,HP1BP3,RPL7 |
| 1.936e-11 | -24.67 | FAM209A (family with sequence similarity 209 member A) | protein interactions | 200232 | 259 | 123 | 19454 | 5460 |
HMOX2,SLC35B4,VAMP5,GJB2,CYBC1,SYNGR1,SLC1A1,UBASH3B,VAMP3,CDIPT,PLP1,TECR,MMD,PLP2,HACD2,TRAM1L1,SEC22B,SLC35E3,GHITM,ENTPD3,TMEM254,NXPE3,TMEM243,APMAP,TEX264,ORMDL1,LRP10,TMEM47,TMEM107,SCGB1D1,CD81,TMBIM6,SLC41A1,ORMDL3,TSPO,ADGRE2,AQP2,BTN2A2,TMEM11,DOLK,TMEM42,SLC35A1,FA2H,RPRM,RHAG,COMT,CNIH1,FUNDC2,AIG1,ANKRD46,TWSG1,YIPF4,UBIAD1,NRM,INSIG2,SELENOK,TFRC,SFTPC,ERG28,UNC50,STX8,RUSF1,TMEM50B,TSPAN7,SLC7A14,GPR37L1,TF,ADIPOQ,DNAJC30,CYB561D2,PLN,FIS1,TMEM100,VMP1,FCER1G,CYB561,TMEM229B,THBD,CNPY3,TMUB2,SEC22A,CD59,CTXN3,CLDN4,BET1,GOSR2,AGTRAP,CMTM7,FAM3C,FDFT1,SMCO4,TMEM203,JAGN1,EMC6,FATE1,FAM20B,SLC38A7,PMP22,TMEM208,PLPP4,FXYD6,STX5,TMEM14A,DEFB121,TRAF3IP3,TMEM97,COX4I2,MFSD6,PGAP2,STX12,NCR3,CYB5B,TMEM14B,AQP3,CTSA,SEC61G,SLC35G2,TMEM147,SEMA6C,PLPP6,SACM1L,TMEM60,TNF |
| 2.104e-11 | -24.58 | negative regulation of transport | biological process | GO:0051051 | 460 | 202 | 18204 | 5365 |
VAMP3,CCR2,ARF6,PPIF,PLSCR1,UFM1,PLN,MIR17,GJA1,TLR2,NFKB1,SRI,NPY5R,MIR424,NHERF1,NPSR1,ATG3,FCGR2B,MIR208B,OAZ2,CAB39,HECW1,PKIA,STXBP6,MIR495,MIR205,HMGB1,TMBIM6,RGS2,CDK5,DERL2,MIR145,RAP1A,ASIC1,CCN3,CRHBP,ERLEC1,RAB33B,LRRTM2,TNF,ADIPOQ,STC1,NDUFAF2,ISCU,MIR24-1,MIR212,OPRK1,MIR153-1,SFRP4,TSPO,GSTO1,SUFU,OSM,MIR301B,LYPLA1,EPO,LGALS3,FABP5,APOC2,FGF23,CRBN,PTPN11,DLG4,LEP,TRIM27,CD200,ATF4,MTMR2,P2RY1,ITGAV,GABBR1,ARHGAP1,KCNJ11,ANGPT1,SCAMP5,ADORA1,OAZ3,NEO1,MIR1-1,SESTD1,OAZ1,MIR143,MIR34A,CD47,MIR873,MIR34B,SDCBP,MIR133B,FIS1,NUP153,CNR1,ATP1A2,CARTPT,PICALM,GHRL,SNX12,PID1,GNAI2,NDFIP1,MIR206,PRKCB,CRY1,PRKCE,CHGA,GSK3A,CRHR1,RAP1B,MIR448,SUMO1,PTEN,CTTNBP2NL,FKBP1A,MIR200C,PPP3R2,PCSK9,OS9,NR1H2,MIR92B,SNX33,VPS4B,DRD3,SELENOS,GRB10,ADTRP,MIR30D,UBE2G2,PPP3CA,DPH3,IL1B,VAMP8,GSTM2,TBC1D4,AKT1,TCAF2,MAP1B,TXN,JAGN1,MIR9-1,NPVF,ENY2,UCP2,SVIP,PIP4P2,MIR144,MIR192,PACSIN3,CHP1,SYT4,MIR146A,PSEN1,ARL6IP5,HADH,INHA,GNAZ,TLR9,MRLN,PKIG,TNFRSF1B,MIR208A,MIR148A,SNX3,MIR129-1,CD36,UCN,FKBP1B,CAV3,MIR33B,GPR35,KCNAB1,CLIC2,CAV1,OXSR1,MIR130B,OPRM1,AKT2,MIR186,VDAC1,LILRB1,INPP5K,HTR2A,IL12A,ARFIP1,SFRP1,CSK,RSAD2,ERP29,CRYAB,GNAO1,MIR107,MMP9,GPM6B,LRRTM1,KCNB1,SLC43A2,ACVR1C,PEA15,RAB23,IL12B,HCRT,WWP2,UBAC2,MIR185 |
| 2.106e-11 | -24.58 | CKAP4 (cytoskeleton associated protein 4) | protein interactions | 10970 | 571 | 233 | 19454 | 5460 |
TMEM38B,MYC,ARMC7,TACO1,LMBR1L,DLST,CMTR1,GGT7,ESR2,ATP6AP2,TOMM22,BET1,FUNDC1,SEC62,PIH1D1,TMEM106B,AKAP1,EP300,RAB5A,EMC1,UFL1,STAU1,LAMP2,WWP2,RAB5C,PTDSS1,DKK1,DDRGK1,ARMC8,RAB35,NKX3-1,FEZ1,NRSN1,STX5,LYAR,RHOH,RAMP3,COX14,STBD1,SOX2,DNAJC25,ISG15,RAB4A,PTRH2,PDHA1,RND3,TAPT1,CCR1,RPL31,CYP2C9,RINT1,EWSR1,PDIA6,KRAS,VDAC1,ATF4,ARHGAP21,GORASP2,MECP2,DNAJC10,UBE2H,CALU,PSPC1,ATL1,SRP54,CTSB,LYPD6,CDC42,RPA2,USE1,SSR1,HEXIM1,LEMD3,TEX264,RAB9A,DERL1,LPAR1,HSPA5,DPP4,SELENOS,DHRS7,FAM20C,PPIL4,COPS5,TMA16,SMIM12,TSNAX,AGPAT1,CD274,SSMEM1,COX4I1,CAMLG,RAC2,ARL6IP5,DNAJC1,RPS16,FZR1,LMAN1,STX6,TMPO,SNAP29,PREB,TP53,DDX42,TFRC,DISC1,RNF8,SLC25A24,STX18,RAB3B,MEPCE,SLC6A8,FKBP8,VEZT,NDUFB7,CUL3,RAB11A,GGH,LMNB1,SCFD1,VMP1,ARF1,GRIA1,RMDN3,SEC61B,GPR89A,TENT5C,LGALS3,PGRMC1,NOTCH2,TOR1AIP2,RND2,OTULINL,VAPB,ARMCX3,DNAJC3,PMAIP1,PXMP2,STX7,G3BP2,SKP1,DNAJC22,PIK3R1,MARCHF5,CDK5RAP3,RHOG,C2CD2L,RB1CC1,PHB1,GJA1,ARHGAP25,BRD9,CYB5A,DNAJB9,KCTD10,TMEM237,WIF1,RAF1,B3GNT2,CSNK1E,MACO1,FAF2,STIM1,EZH2,RPN1,CYB5B,TMT1A,SCD5,EMC8,TRIM37,PRELP,GOLGA7,RETREG1,HS2ST1,CIAO1,HMOX2,CCNF,EIF2AK2,PTEN,ZNF622,RHOJ,UBB,VIRMA,SEC63,RABL3,ATG16L1,ARHGAP1,SEC22B,ST7,GRM2,SLC12A2,TMX4,PDCL,RPA3,SYVN1,MTDH,SPCS2,RTN4,SQSTM1,YKT6,SLC7A1,FBXW7,TMEM209,EI24,MOV10,TMEM199,SLC25A46,LAMP3,HM13,MED21,POR,ESYT1,UPK1A,OSBPL8,STYK1,PTPN1,SRPRA,HACD3,HSD17B11,CDCA3,ARF6,TOR3A,CCDC47,LBR,HSPA13,SEMA7A,SRP72,FAM169A,NSDHL,IGF1R,EMC2,DNAJC30,VWF |
| 2.109e-11 | -24.58 | ATP6V1B2 (ATPase H+ transporting V1 subunit B2) | protein interactions | 526 | 222 | 109 | 19454 | 5460 |
KRAS,ZBED1,EMC8,RUVBL1,SSRP1,TFG,AHCYL1,ZYX,PABPC1,CCT8,EZH2,TUBB4B,RAB4A,PRKAG1,RAF1,SUPT5H,SOX2,CYB5R1,TUBA1A,EEF2,NDUFS8,UQCRH,HSP90AB1,SWAP70,PHB1,TLDC2,PBDC1,ATP6V1A,SKIC8,CBL,MED4,NDUFB8,LRRC57,RAB5C,NDUFV2,ATG7,SLC38A9,ATP6V1G2,STX7,ATP6V1G1,SKP1,TBC1D24,RAB5A,NDUFA5,PRKAB1,ATP6V1C1,ATP5F1B,LAMTOR3,ACTB,UBE2V2,POLR2B,ATP6AP2,TRMT6,SRXN1,CYB5R3,GCC1,LAMTOR1,ATG3,RPS5,CRMP1,RIT1,NSA2,CUL2,RAB11A,STX16,PDE12,CSE1L,RAB3B,MSH6,SFXN1,EMC2,NDUFS3,NUPR1,MTCH2,DDX39A,UBE2V1,PRNP,STX6,G6PD,PTPN1,POR,TMOD2,ATP6V1D,MOV10,LAMTOR2,GMPPB,ROGDI,RAB9A,JUP,RPRD1B,PTP4A2,FGFR1,CYC1,EEF1E1,ATP6V1E2,UQCRC1,TMOD3,RAB14,VIRMA,VAMP3,UQCRC2,GANAB,NAPA,UBE2H,NDUFB10,RAB2A,ATP5F1A,HMOX2,DNAJC5 |
| 2.144e-11 | -24.57 | COX4I1 (cytochrome c oxidase subunit 4I1) | protein interactions | 1327 | 409 | 177 | 19454 | 5460 |
TMEM38B,COX6B1,ISCA2,TACO1,VDAC2,DLST,CCDC90B,ATP5F1B,ESR2,LAP3,TOMM22,BET1,NDUFAF3,UBAC2,NDUFS2,EMC1,SSR3,PHB2,NDUFV2,CTNNB1,DEGS1,NDUFB8,DUSP6,CORO1C,UQCRH,RMND1,COX14,ETFB,PDHA1,FAM136A,MYO1B,KRAS,VDAC1,COX7B,NDUFAF2,MTPN,CISD1,DNAJC10,UBE2H,CALU,UQCRC2,MRPS28,SUCLG2,RPA2,SDCBP,COX7B2,SAMM50,GSTP1,CYC1,MAIP1,DLAT,PRDX6,GFM1,SLC25A51,MRPL41,HSPA5,KARS1,COX5A,TPM3,TUBG1,SMIM12,TMEM70,MRPS9,SSBP1,SDHB,COX4I1,LMAN1,MYL12A,MTCH2,HADH,APOO,DUSP1,GLRX5,H2AX,GPD2,TMEM165,MRPS18B,CLPB,BCAP29,DUSP19,FMC1,AUH,NDUFB7,PYCR1,PMPCA,CUL3,TOMM40,PIGA,RIT1,HTRA2,ACTB,CHCHD3,PARL,GNB1,NDUFAF4,CLIC4,MTX2,TIMM13,TIMM29,VAPB,ATP5PO,NDUFA5,EXD2,PMAIP1,HADHA,HSCB,CLPX,PDIA3,MRPS35,PPM1B,HAX1,MRPS26,PHB1,COX7A1,ATP6V1A,GATD3,NDUFS8,TLCD4,FAF2,NDUFS6,GPAA1,HSPD1,PREPL,NDUFA4,HINT2,COX8A,G3BP1,ETFA,ATP5F1D,IMMP2L,RALB,NDUFB10,PYCR2,TUFM,FXN,GANAB,CHCHD6,MGST3,TMOD3,COPE,UQCRQ,VIRMA,TIMMDC1,SPR,UQCRC1,CRAT,MRPS34,COX6C,HSP90B1,MTRES1,RPA3,PDHB,CALR,EMC4,SMDT1,DNAJC4,AIFM1,TIMM8B,CDCA3,ATP5PD,DBT,TOMM70,SLC25A12,PLGRKT,TMEM126A,NDUFA2,PPIF,TIMM8A,NDUFS3,SFXN1,EMC2,HSD17B10,TRIM63,DNAJC30,DUSP21,FASTKD5,RIGI |
| 2.167e-11 | -24.56 | intracellular transport | biological process | GO:0046907 | 1182 | 451 | 18204 | 5365 |
CASC3,ARF6,RAB9B,TBC1D17,NEFL,SEC61A1,LMAN1,TBC1D5,TRAPPC10,TRAPPC6A,PLEKHJ1,RAB31,FBXW11,CTTN,CITED1,TRIM23,NUP35,STRADB,RSRC1,TBC1D10C,PEX3,TBC1D13,SPRN,PLEKHA8,TIMM23,TOMM20,CDKN1A,BORCS8,CIDEB,HSP90B1,PREB,TRIM46,RHOB,PLEKHF1,RANGRF,CORO1C,SEC22A,RAB6A,STX1A,CDK5,RAB11B,ARL4D,VPS28,CTDSPL2,RAB2A,SEC13,ANP32A,ERLEC1,ING1,TMEM106B,RAB11A,RAB6B,VAMP7,POLDIP3,VAPB,APPBP2,GRPEL2,TMEM50A,RANBP6,ARMCX3,SCFD1,CHMP4C,ARCN1,ANKRD50,DESI1,RBM15B,LIPA,RPL23,BET1,YIPF4,YIF1A,CCDC22,CDKN1B,GLE1,UFD1,TMED5,FYTTD1,CHMP5,STX12,MREG,FBXO22,IPO8,RAB32,SAMM50,SRP54,KPNA2,SNX2,TRAK2,AP1AR,MKKS,CDAN1,TMED7,NETO1,TOMM70,RPAIN,RPS15,TRIM27,ARF4,NUP42,TMEM87A,TRAM1,ARHGAP1,HSPA8,LARGE1,CHMP1B,KIF3B,EHD1,VPS4A,NCBP2,ARHGAP21,BLOC1S2,GNPTG,TP53,MAP1S,NOP9,STK4,ARF1,ATP1B1,NAPA,POLA2,BECN1,TRAPPC3,KIF1C,RAB13,PICALM,VTA1,NDFIP1,BAG3,ARL5B,AP5M1,AFTPH,RAB28,HGS,WDR11,SLC66A2,RNF126,VIPAS39,RABL2B,CSE1L,COPZ2,HPS6,XPO5,OS9,ACTN4,SNX33,TIMM10,AP5S1,THOC3,VPS4B,ADRB2,C9orf72,TOMM22,WASL,TRIM37,CMTM6,RABL3,PEX13,NAPG,HSBP1,KXD1,RAB1B,EIF2D,RAB29,SEC22B,CPT1B,CPT2,KLHL12,DPY30,STBD1,LCA5,PPFIA2,OSBP,CHP1,CCDC186,UBE2I,EGR2,MTM1,AP2A1,ZMPSTE24,HSPA5,TNPO3,IFT22,ALKBH5,SNX3,TRAM2,IFT57,AGAP2,RAB1A,BLOC1S3,PLEKHF2,AP2M1,LCA5L,VTI1B,CDR2L,SMG5,SYNDIG1,HSP90AA1,STX8,SNAP25,STK3,SLC48A1,MTCH2,CNIH4,TRAPPC13,RAB18,NXT1,YWHAH,RAB9A,ARFIP1,TUBA1B,TOMM40,GOSR2,IFT172,HSPB1,GOSR1,SLU7,CDC42,FAF2,DNAJC19,HNRNPA1,PREPL,SEC61G,THOC2,TMEM50B,CLBA1,VAMP3,PICK1,VPS54,TRMT10B,RAB35,YIPF5,RAB19,STX6,SLC25A20,LAMTOR1,USE1,NDP,TSPO2,VPS16,RAB5A,SSNA1,DRD1,TIMM8B,HCLS1,NHERF1,SRPRA,TRAM1L1,TUBB,ARL6,SYBU,EHD3,NUP62,PML,HDAC6,STX16,ZC3H11A,GRPEL1,TMED9,STX11,RINT1,SYK,CLU,RAB14,SCG5,DERL2,TMEM108,RILPL2,EIF4A3,NUP37,NXT2,STAR,TIMM13,SEC63,NPC2,YKT6,UBAP1,SCYL2,CD63,XPO1,STARD4,BORCS5,AP3S2,TOMM7,STX17,TIMM21,BICD2,CAMK1,TMED3,ACTR2,BET1L,RGP1,BLOC1S5,SNX11,CUL3,AGK,SNX1,MTX2,WDR19,ALYREF,RAN,PIK3R1,ACAP2,LYSET,BORCS7,TOMM6,CTSA,KDELR1,TRAPPC4,SEC61A2,SYS1,SEC62,SNX17,AP2S1,HIKESHI,PHB2,SQSTM1,HNRNPA2B1,TRAPPC2L,STX18,CHTOP,NDE1,MGARP,CALY,SURF4,ARL4A,GPIHBP1,STAU1,RAB8B,TMCC1,STX10,THOC1,ZFAND2B,MAGOHB,PHAX,TOM1,SEC23A,STX5,ARFGAP3,DYNLL1,IFT52,PAFAH1B1,NUP107,SNX10,RAB22A,NUP153,NUP50,SOD1,SYNRG,CCHCR1,SNX12,FHIP1B,TIMM8A,SEC61B,RAMP3,FAM91A1,KPNA6,TEX261,SYVN1,TUBA1A,ABCE1,SSX2IP,BCAP29,DERL1,STXBP1,TSG101,DDX39A,TFG,PCSK9,STX7,TMED4,VPS26A,UBXN6,SELENOS,VPS39,PEX26,FAM53B,PPP3CA,LMNA,AKT1,PHETA2,MAP1B,VPS26C,DYNC1I2,KDELR2,IFT25,ENY2,RAB5C,MAGOH,AP1M1,NFKBIA,ROMO1,SNX5,CALR,NSG1,SNX18,EHD4,SFN,SYT4,HM13,TRAPPC1,PPP1R10,TIMM17A,CACNG3,EMP2,SMURF1,FAM53C,LEPROTL1,RHOBTB3,CHMP2B,SNAPIN,VPS18,PRKAG1,TRAPPC3L,SRSF10,PAX6,CHMP2A,XPOT,TIMM29,TXNIP,SAR1B,PEX5L,TRAPPC6B,CLIP3,LMNB1,MIA2,VPS33A,TNPO2,VPS26B,TMED1,AP1G2,LDLR,AP1S2,LAMP2,AHCYL1,ERP29,SEC22C,EIF4E,TRAF3IP2,DDX39B,UBB,CHMP1A,DYNC1I1,THOC6,BBS5,DNAJC27,BORCS6,MYO6,RAB23,COPE,ARL11,KPNA1 |
| 2.248e-11 | -24.52 | negative regulation of cytokine production | biological process | GO:0001818 | 381 | 173 | 18204 | 5365 |
BANF1,MIR215,MIR221,MIR155,DICER1,MIR130A,MIR206,NDFIP1,IL1R2,MIR20A,GHRL,MIR320A,DEFB114,MIR488,OAS1,CD34,MIR125A,BST2,ACP5,MIR708,MIR200C,CD200R1,NLRP6,SELENOS,RNF128,TLR6,CCR7,MIR152,TGFB3,MIR136,PTPN22,OTUD7B,MIR877,TNFAIP3,GSTP1,TGFB2,CRYBA1,MIR192,IGF1,PPP1R11,IFNA2,MIR21,INHA,MIR146A,LILRB4,MIR149,MIR504,IL4,RGCC,NPTN,MIR383,TIA1,MIR31,SOCS5,IL20RB,MIR197,MIR210,ANXA4,MIR129-1,MIR204,FURIN,NMI,CHID1,TYROBP,CPTP,IFNB1,PPARA,BTN2A2,PRNP,MIR132,FOXP3,IL12A,CD274,LILRB1,MIR194-1,RPS6KA4,CD83,PYDC2,MIR107,MIR142,IL6,CSK,MIR185,IL12B,MACIR,MIR106B,MIR657,MIR378A,PDCD1LG2,SFTPD,MIRLET7C,F2,XAF1,NLRP3,MIR373,MIR222,CD2AP,MIR181D,MIR214,MIR17,MIR338,ARG2,NFKB1,MIR16-1,PML,MIR105-1,AGER,MIR361,PYCARD,NFKBIL1,MIR98,FCGR2B,BCL6,EPHA2,HFE,MIR205,HMGB1,ASB1,NMBR,TUSC2,SERPINB1,CX3CR1,MIR145,MIR920,MIR101-1,MIR24-1,CX3CL1,XCL1,MUL1,IL10,TWSG1,ADIPOQ,TNF,VSIR,PTGER4,TLR8,GPNMB,MIR106A,HOMER3,KLHL22,UFD1,TSPO,MIR100,CUL3,MIR874,CHRNA7,EZH2,MIR195,IL23A,MIR181C,PPM1B,MIR28,RAD21,MIR140,CD200,TLR4,TRIM27,DDIT3,KLF4,PTPN11,MIR590,MIR147A,ANGPT1,FGFR1,SRGN,MIR26B,MIR34A,IL13,LGR4,MIR15A,PDCD4,IDO1,IFNG |
| 2.290e-11 | -24.50 | membrane-bounded organelle | cellular component | GO:0043227 | 13662 | 4156 | 19108 | 5553 |
DESI1,COX4I1,CRY1,SSRP1,RAB37,LEMD3,RPL26,SEC14L1,B4GALT7,ZBTB42,VPS16,ADAMTS1,OTUD7B,ABHD10,IRF8,CRAT,ABHD2,COMMD8,LMBRD1,MCM6,H2AC25,HERC4,MRPL16,IRF2,RBIS,TAGLN2,JAK1,B4GALT6,FABP5,LRRC8B,NOC4L,PLCB1,ELK1,CNR1,PCLAF,FITM1,GNAI2,CFAP20,CTNND1,TFIP11,EMC4,OR51E2,DDX4,TOR1B,ST3GAL4,ESR2,COPS5,GSTA2,IGFBP4,LAMTOR2,TLR7,MCM8,MIR146A,CYP39A1,SYS1,APTX,GASK1B,TMEM89,SRSF2,MSMO1,APOBEC3G,ARFGAP1,HSD17B10,MIR92B,ELOVL4,GAD2,PDCD10,RPL10L,JUN,C1GALT1C1,SUMO3,CETN3,RAB29,TRIM32,PSRC1,UNC50,ZNF287,AK2,RAB6B,CHCHD6,MIR24-1,PAK1IP1,GABARAP,SLC41A3,PLA2G5,BRMS1L,CFAP73,EIF4EBP2,NDUFA1,CPE,TMEM97,LGALS3,BPIFA2,PNPLA8,R3HDM4,KDSR,RB1CC1,RPS13,MINAR2,EPOP,HSD17B11,ZNHIT6,SERPINB6,UTP15,MRC1,LUC7L3,SLC7A14,SNX2,SRI,WTAP,SNX22,CELF6,THRAP3,TMEM70,GORASP2,MIR17,GLRX2,LSM10,GNG2,LY96,DMAP1,SOD2,NLE1,TSPAN5,CFAP36,RAB3D,ZNF704,BUB3,LRRTM1,SNX17,MAIP1,LAP3,AKAP17A,STX5,EIF5B,CHRM3,MIR152,HSDL1,OSGEPL1,DTD1,SLC8A1,STX10,MRPS25,PACSIN3,MX1,MRPS28,TP53INP1,PYGM,HDAC6,SLC25A11,FZD4,BPIFB1,TCEA2,GPR85,FAM107A,MZT2B,MED21,MTG1,NEUROG2,DPEP1,TICAM2,IFT57,GBE1,ZNF576,ADNP,MINDY3,HS3ST5,CLK4,COX19,RNF40,ACTR2,SVOP,DPH3,AQP2,RPL19,VDR,TOMM40L,SNAPC1,NAIF1,ANXA4,VAMP2,SLC12A2,SPCS1,MCRIP2,SNRNP48,ATP5MC1,CHST9,PRSS12,GRXCR1,CAV2,CPSF1,GINS3,SFRP1,GOLGA5,OCEL1,UQCC6,MTA3,ZNF518B,TRMT112,FA2H,IKBKB,MPST,GSTA1,BSCL2,LIAS,NAA16,PRDX6,TRAM1,PPP1CB,STX18,PRRC2A,UPRT,CCT7,CYC1,PARP2,MAP3K14,ZBED4,PRMT2,WDR83OS,CBLL1,ZNF501,ORC5,LAMP2,TMOD1,LBX1,NDUFAB1,ATXN10,VGLL4,ATP1B1,EEF1E1,HDHD5,ZNF345,GEMIN7,EXOC3,BAHD1,PLP2,ACO2,B4GAT1,SLC15A2,ZNF330,TRMT10B,XXYLT1,NAP1L3,MAGOHB,CARD19,EHD1,RNF208,COMMD9,VAMP5,LYPLA2,PRKAG1,DEFB1,PC,COX5A,QTRT2,TOPORS,NOS1AP,UBAC2,FKBP4,SOD3,SH3BP4,ENTPD4,FAM168B,NCSTN,MIRLET7C,H2BC14,PRKRA,PLEKHO2,GOLGA7,SOX9,GOLPH3L,CAVIN2,PSMB5,MRPL9,COX8A,ZMYM3,ARPP19,TMEM176B,SYNPR,STC1,RPLP2,FGFR1,RFX4,ALG5,FBXO32,KRT7,H2BC1,TSPAN3,RDM1,ZFAND2A,BGLAP,RPS28,B4GALT3,BRMS1,RPL6,GAMT,SLC13A5,B9D2,USP16,HNRNPH2,MAP2K6,DPAGT1,MAPK4,FTSJ1,ARL2BP,GLIPR2,HNRNPC,CLIC2,TOMM22,WDR5B,HPF1,WDR3,NLRP2,B3GALT1,KCNJ10,PELP1,SH3BGRL,SLC2A8,HMX1,CAPZA2,NF2,SPRYD4,FAF1,BMP1,SNRNP27,CSTF3,EIF2S2,TTR,RANBP1,DRAM1,MYL6,TMEM91,MRPL41,MIR34A,SYNGR4,PSMB9,TGIF2,NFKB1,GLT8D2,MDH1,SLC25A27,SLC25A42,RASL11A,NOP53,UBE2M,SPRED1,TSR2,OGDHL,CAMP,DIO3,CAMSAP2,MIR10B,EMC9,PIP4P1,PRR19,DYNLRB2,SLC30A5,IL6,NR1H2,SIT1,ELF1,MRPS35,CD1B,MKLN1,BABAM1,PRICKLE2,CSE1L,ATF4,SDHAF4,MIR130A,CALR,PPAN,SERPINH1,AP1M1,ST13,SNX18,CNIH4,POMP,FAM20B,MCAT,CEP41,TOM1L2,NLRP1,SDHAF2,MLLT11,CAPZA1,MIR198,MGAT1,DIPK2A,PPIA,SPATA2,SELENOI,SNRPB2,MMAA,NLRP6,CYB5R1,RIT2,S100A8,TAB1,METTL18,MRPL20,BUD31,FGF7,PSMD3,CDKN3,APEX1,CD247,BCS1L,WWP1,CHDH,GAL3ST1,PEX3,SLC25A31,HNRNPH3,TMEM203,OAS1,HBB,SST,RBM15B,MIR26B,MRPL23,GNL1,RGS2,PAXX,TNF,SRP54,CFAP95,RPL7,PITPNB,RIOX2,MAFG,BACH1,RANGRF,TNFAIP8L2,SP1,AASDHPPT,FTH1,AZIN2,OXSR1,DECR2,TYROBP,CBLN3,FKBP10,BICD2,IRF6,NGDN,PSMB10,RNASET2,ATP1A3,IDH3B,FGF23,DNAJB2,SCG5,EEIG1,RUNX1,INSM2,RNASEL,FAM50B,DENND6B,GKAP1,ZDHHC17,ST6GAL1,CYP27B1,B9D1,VDAC1,PIGY,TMEM50B,TRAPPC4,RAG1,TAF11,ERH,YWHAB,GALNT17,CYB5B,IRF2BPL,CCDC172,TGFB2,ATP5PO,TRIM26,ABCG2,MOB3B,MAPKAPK3,TNFAIP1,BBS5,HPGDS,NCK1,TUBB4B,PTGES3,HACD3,TMED1,MIR423,ZNF581,GALNT4,POLR2G,OIP5,SERPINB1,LITAF,CD34,SNCG,TMEM127,TXN,ST6GALNAC3,ATP6V0E1,SLC2A3,TMEM208,NME2,PLPP6,GJB2,HSD11B1,FBXO25,MX2,TF,VPS4B,NACC2,SPOPL,FGF12,TMED5,CDC40,PPIF,CORO1C,PPIB,MIR125A,LPAR1,JMJD8,INTS6L,SNRPB,COX4I2,CD248,ROMO1,S1PR4,MRPL52,RAF1,TLR6,SPATA4,ING1,DAD1,TIA1,TMEM198,NR2E1,VPS18,JAKMIP2,UFD1,RAB1B,CDK5RAP3,RBM34,PHTF2,EHHADH,RPL7L1,SLC38A7,TEX12,SLC38A1,MAGOH,NDUFB10,CDK5,TP53TG5,SERPINB9,MOB4,TTC1,SNAI2,TRAPPC2L,UBE2E3,CHIC2,RP2,MUL1,POU3F4,SIAH1,YAF2,ZNF664,WEE2,ITGB8,GTF2E2,ZMAT5,SPATS2L,CCS,ZYX,SPEF1,SLC35A1,ATG7,MANSC1,ZNF575,MSRB1,RABL2B,RAB3A,GRSF1,RBBP4,MAB21L1,TPM3,AK3,IFTAP,FEN1,MSX1,TLCD3B,HEXA,GID8,GNG7,DUSP3,TOMM40,DICER1,ATG16L1,FBLN5,UBXN10,GNPAT,UGDH,RNF133,IL12B,DCTPP1,NDUFB8,REG1A,SEPHS1,RCBTB1,MTCH2,SMCHD1,CD59,SERTM1,AP5M1,HCFC1R1,BRINP3,SPR,ENPP4,TIMMDC1,MECP2,ASPA,TDRP,TM9SF4,POU1F1,RAP2C,CTTN,DR1,H2AB1,TMEM115,GRAP2,RPL7A,SNIP1,PREB,TRAM1L1,CD40,NUF2,EIF3K,DDX5,RAB9B,EHD4,NMRAL1,ARL5B,CEP19,CIB2,TASL,ARFGAP3,DYNLL1,CHST13,VPS54,SLC39A9,SDHAF1,UBA52,CFAP298,TSPO,CFDP1,PTP4A3,ZNF362,ERG28,OAZ1,PROS1,RAD1,NOSIP,PSMA3,SLC52A3,PIGA,NT5C3A,CSNK1E,SUGP1,RAB33A,HEXIM2,CCDC69,DDX39A,SDC4,MARS1,YIPF4,UBL3,EHD3,KDELR1,EZH1,TACR3,SLC48A1,GLRX,RPS16,SNX5,NUPR1,CYP21A2,NDUFAF6,DHX16,ZBTB25,CATIP,H2BC12,CCDC92,UBE2B,EPHA4,MIR31,LRAT,CYB5R3,RNF121,FANCG,GABRA2,BCL2A1,SAT2,PRKAB1,SLC35E3,ARMC8,CSKMT,TRIM29,BAALC,RAB18,NCDN,GNPDA2,CEBPE,BORCS8,CYP1B1,FCHO2,BLOC1S3,HSPB2,POLR3F,NUP107,CYRIB,NPPC,AIFM1,NHERF1,ARFIP1,ATP5PD,NAE1,PRSS37,CGGBP1,COA1,MIDEAS,CCNY,GH1,CSNK1G3,ABHD6,STX7,PTPN22,PSMA5,NOL7,SF3A1,GABARAPL2,PSEN1,CNTN1,MIR30A,TOMM7,TOR1AIP2,IFIT2,LSM6,CLEC18A,ZNF655,SLC25A17,KIF2A,KICS2,LCA5,CDC42EP4,WDR55,CKS1B,SLC30A7,TSPO2,TXNRD3,S100PBP,DNAJC19,MIR193B,MRM2,RBM12,INSIG2,IGF2BP1,SSX2IP,MACROH2A2,S100B,VRTN,TAFA1,CDC5L,GADD45B,AKT3,SOST,MIR107,RNF34,LHX2,SETD9,CD164,IRAK1BP1,B4GALT1,CYSTM1,NDC80,LCMT1,MDFI,EXOSC8,LDHA,CRYZ,STX17,SSPN,ABHD14B,TMEM107,NSA2,DTYMK,CYTH4,XBP1,SLC1A1,MAD2L1,TICAM1,PSMD7,PRR13,SDF2L1,TRAK2,DUSP9,RCL1,RFC5,TLR3,IL6ST,TBC1D10C,ENPEP,HDAC3,PAAF1,PFDN4,MAN1A2,UBA3,METTL22,MIR23B,STAT2,TMEM165,CFAP418,DYNC1I1,NTRK2,HNRNPK,STAT6,SEC61A2,TMEM117,FIS1,CRKL,CDIP1,GRM1,ATP5IF1,ATP2B4,PFKFB2,STOML2,ENO1,TGIF2LX,DAPK3,SNRPD3,TMEM170A,TMEM50A,MRPL24,DCUN1D5,PSMD12,TMEM126A,FOXA3,LIMS2,LRWD1,TEF,AMY2B,HM13,INTS12,TLR9,NPTX1,OTX2,NFIL3,STN1,ENDOD1,ACOT8,TFPI,ORC6,OCIAD2,OPRL1,ACOT13,CUTA,CDK2AP2,RPS24,TMX2,ANP32B,CRTAP,HP1BP3,USP46,PRM1,TMIGD1,CAMKV,MRPL10,MIS12,DNAL1,SRGN,EXOSC4,TRIM45,ALYREF,PPID,AP2A1,DRGX,APOBEC3D,NKX3-2,ERLIN1,SCAND1,ANAPC2,FASLG,ANAPC4,CHRAC1,NAP1L5,GTF2A2,STPG4,PDE4B,FCAR,RRAGB,NAA60,TNFRSF1B,GATD3,ENKD1,CD47,SUV39H1,HECTD1,MTA2,TMEM237,POLB,STRADB,SCYL2,PHETA2,TOM1L1,PDE8A,RARS1,COPS7B,KDM1A,HADHA,TNFAIP8L3,PPFIA3,SLC38A9,AKT1,RMDN3,NAB1,CRHBP,ICAM1,GPRASP3,CDK8,MCHR1,TRAPPC14,CXCR1,TNIK,CCR6,STK24,DCAF5,ACTR1A,TLR4,SLC37A4,SIVA1,MIR342,CD1C,PLEKHA8,COPS2,FAM20C,STMN2,MEST,DNAJB9,CD4,IFT22,RPL12,PNMA3,CRYM,LPCAT3,POLE3,GABPA,PPP1R10,NIBAN2,PCGF6,ATAD1,NUDT16,CHCHD4,DROSHA,CHMP1A,FIG4,H1-3,GLRA1,TMBIM6,CAMLG,ZNF862,SPRY1,DLG4,SNN,ZCRB1,BRCA1,ZCCHC17,CYP2R1,F11R,MGAT4B,GSTM2,RBP2,ADD2,NUDT2,PIWIL4,ARF4,CD14,GLUL,AGO1,TOMM20,COA5,SLC25A1,HOXC4,NBN,MPHOSPH10,RORB,MEAF6,P3H1,PDCL,ZFAND2B,NDUFB4,CDKN1A,DKK1,S100A10,EFHC1,PPP2CB,GADD45A,CREBZF,KCNA2,CHGA,SNAP29,LANCL2,SRPRA,RPL10,TOLLIP,RPS23,BRIX1,FIBIN,CFAP119,RAP2B,TNPO3,YWHAZ,DEGS1,PARL,CAMK2N2,EMILIN1,HHIP,PNMA2,AKIP1,FHL3,TRIM68,SURF6,STX6,GTF2B,PRKX,PDE6D,SPACDR,PLPPR1,CD86,H2AC4,PAK6,PPP2R5A,IL15,TEX261,GRAP,SMARCA5,NCAPG2,ASTN1,BIRC2,HADH,MAPRE1,BEND6,SETD5,SFN,ASPM,PNP,CEND1,TWNK,ZNF177,WSCD1,CRYBA1,TNFAIP6,FAM91A1,RXRG,GCA,CSRP1,ARPC3,ERLEC1,PDE6A,RBFOX3,PWP2,ATP5MG,ARPC2,PAFAH1B1,DNAJC25,ZNF687,MRPL57,PALS2,GSTP1,ZSCAN25,GPAM,CYP4F12,KRR1,COX6B2,SPRN,AKR1C1,TMUB1,KARS1,USP14,RTF2,PML,TOP3B,ILVBL,TBC1D25,FLRT3,HAS3,PSEN2,SPON1,STBD1,CBX3,RAB11A,RGMB,TLDC2,TUBB,RNF115,NFE2L2,KLF10,NPC2,EEF1A1,RETREG3,ZFP64,IGF1,TRIM36,TMEM179B,CYTH2,TIMM8B,CLVS1,FRMD8,ZNF22,EPS8,FAM210A,HOXB8,BCL10,GPR37L1,MIR619,MIR215,EXOSC3,CEBPG,GTF2F1,PRNP,PRDX3,NONO,STK26,STAR,MYORG,RFC2,GABRG2,NXT1,INO80C,CIDEB,RILPL2,CUL2,EDF1,HYPK,PSMD4,NPY,TRMT61A,RPS4X,CPSF2,UFM1,MAD2L2,PSMA2,DUSP26,GIMAP2,IPO8,STT3A,EMC6,RAB28,NUFIP2,FBXO3,ZCCHC12,CDNF,CYP17A1,GLIPR1,PAFAH1B2,STARD7,MRPL34,DBH,PQBP1,PDIA3,FMOD,TRMT1L,RAPGEF5,NDUFC2,EIF2AK2,PXMP2,ARHGAP15,FHIT,POLR1H,CBR4,FAM8A1,MZB1,PPM1M,BNIP3L,MAVS,GAS8,PYCARD,CDH13,TMEM100,MEF2C,TRA2A,GGCT,PBLD,ITGB5,PSME2,TRAF7,HBA1,KLK5,SNX10,ZC3H11A,CHMP4C,TFRC,CSRNP3,MAEL,MED11,ST8SIA4,COA4,ELOVL7,ST3GAL5,YPEL4,GPBP1L1,SRFBP1,ZCCHC7,SEC61G,NDUFB7,ARHGAP5,EIF3G,ILF2,G3BP1,AZIN1,SRSF7,UQCRC2,TAPBP,CEACAM5,NEK2,GAPT,ARMC1,PTN,NAA35,GNG12,CALY,GALNT1,TMEM33,F7,SCG3,DLX1,GCNT3,CYP11B1,MRPL36,FLRT2,RETREG1,HEXB,BST2,CACNB4,TUSC2,AQP4,ATOSB,BAG3,LINC02914,PPARA,TIMM21,AIPL1,ATP6V1C1,NAA30,OVOL1,PSMB1,COQ10B,LBR,MBD3,TMEM126B,NGRN,DET1,LRP6,CYBRD1,CCT2,CREG2,KANSL3,RNF139,ZNF343,MIR20A,SMAD2,SLC1A3,PPWD1,FBP2,NOVA1,ALG2,FAH,MRPL47,TRIM27,GNB3,NGB,TNFAIP8,PKIA,RAB5A,NLRP3,CD52,ADGRG1,SLC66A2,OSBPL8,PAQR3,SGMS1,TRIM8,PMP2,NUDT12,COPS7A,MIR100,MED13L,KLHL7,RAC2,HLF,DPM2,AOX1,CENPM,NR4A2,YWHAH,DUSP21,TMEM106C,FAM149B1,RNASE1,DDT,RRM1,LRRC8A,CTDSPL2,PDP2,SELENOS,GEMIN8,RPL15,DNPH1,PTPN5,RPS20,LCP1,DENND2D,TRIP4,SRPK2,GDE1,RPL9,ADGB,FCMR,LDB2,FAM241A,UST,NCBP2,CCNH,DUSP10,RNF187,ARHGAP1,RGN,EGR1,DBR1,VPS39,ISX,CPSF4,VPS4A,LIMD2,CTDSP2,FCGR1A,LAMP3,LSM2,PDE9A,HELLS,DDIT4,OTULINL,CMC1,PRMT5,CDK5R1,KLF4,GNPTG,DTWD2,TAF7,PDHA1,DDRGK1,RSBN1L,RHOB,NDUFAF3,PROM1,ANP32A,PPP2R1A,SEMA3C,ARMCX3,HAX1,CIBAR1,DDAH2,NECTIN2,ZNF692,NR1I3,CTBP1,HIGD1C,TMEM174,SPATA6,NDUFS3,DNAJC30,TMED7,MAP1LC3A,PIP5K1A,PI15,TRUB1,CHI3L1,UBAP1,SURF4,DHX9,MCCD1,AJM1,SNX12,MMADHC,CXCL12,TPT1,MIR192,F2,ANKRD49,CRHR1,PHC1,ZBTB38,PAK2,NUDT1,EIF2S1,ROCK1,UBE2I,ADCK1,TXNL1,CLDN8,RPL17,LSM8,PIK3R2,DRG2,TMEM256,HSDL2,CDCA7L,SAR1B,S100A11,LEPROTL1,ISOC1,MRPS11,DMPK,PRCP,ACTL9,ENO2,P2RY1,SMARCE1,VAMP3,SAP30,TLR1,EXOC8,FBP1,SPTSSA,CGRRF1,CASP12,CATSPERZ,RAB3C,RNASEH2C,NAA50,DYNLT3,RAP2A,STAT5A,RWDD3,RFXANK,EGR2,FAM241B,GPR83,RNF126,IFI35,MNAT1,AKR1B1,EIF4A3,SV2B,CTSK,CHST7,PSMD10,CREB3L4,HAPSTR1,CXXC5,SIRT7,TRIM52,KDELR2,SLC25A51,HENMT1,PYURF,PITPNA,FAM76B,YIF1A,PSPC1,PRSS8,CFAP61,TMEM177,RNF14,REEP3,CAV3,SLC25A39,MTX2,APOC2,SMCP,MED23,JAGN1,CPT1B,CSGALNACT1,SNRPD2,UBE2D3,STOM,ZBTB18,ADSS2,ISCA2,SPMIP6,SAV1,TTC23,CACYBP,FAAP100,IMMP2L,CKB,MED29,PLEKHO1,PEBP4,SNRPN,MRPL40,TNFSF13,DNAJC10,TMBIM1,UBE2H,MSH6,MAGEC2,MIR101-1,GLRA2,TAF2,PABPC5,PFDN5,MAP1LC3B,EMC2,NUDT4,CMKLR2,SPMIP5,IMP4,PPIG,VPS33A,INPP4A,GPNMB,ZNF319,MARVELD1,ADIG,FOXC2,NICN1,RHEB,FOXI3,TAX1BP3,PHYH,KLK9,GOSR1,P4HA2,FGF10,PDE12,SYNGR1,RPL13A,TCF19,HPS6,OSBP,RDH12,H2AC1,NRBF2,RAB31,TAF1D,ARL6IP5,BRI3,DNAJC8,MTARC2,SLC25A5,MIR671,ATP5MC3,AQP3,IRF9,SSR2,CLDN14,BAK1,ZNF207,RPL22,WDR20,TFEB,UPF3B,RAB13,SCAMP2,CCDC47,ALDH1L1,DCUN1D1,POP5,MED31,SEPTIN6,NKRF,SMC4,MAT2B,MMP9,EXT1,KIF3B,SELENOM,DCLRE1C,CCDC3,SIX5,PMAIP1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AM3C,CYP7A1,WWP2,KLHL22,RPLP0,GTF2H4,EDEM1,FAS,CYB5A,CFTR,MIR338,APPBP2,OPA3,CUL3,RMND5B,SMARCB1,RFC3,ACADS,SELENOT,CMBL,TSPAN15,SMN1,C9orf72,VLDLR,SEC62,PYCR2,UBP1,TENT2,ARB2A,RAB4A,PCSK2,SESN3,SHOC1,TADA1,GTF2F2,LIPT2,PIK3R1,RTN4,RTRAF,TAPBPL,PCGF2,RSPH1,UCP2,CHCHD2,MTF1,HINT3,EXD2,SACM1L,GNAZ,MSANTD4,HINT2,SMAD3,GMDS,POLR2L,NDUFB6,SNX33,SNRK,MAGEB1,PEA15,PAX6,COIL,CLVS2,RNF41,CALU,TAFAZZIN,DGCR8,ZNF574,SLC17A5,FAM110B,NOL4,GGTA1,TIMP1,PIP4P2,PCBP4,TXNDC12,PRKCE,KDM2A,TMEM95,OAZ2,TRIQK,ZGLP1,SPIN3,LPXN,NDUFAF2,LARGE1,TSN,SURF2,UBE2F,ACTL6B,UBE2A,GABRB2,ARRDC3,RAB22A,TSEN54,EED,IL23A,MLH3,UAP1,MIR638,ZMAT3,PPP1R1B,DDX46,PKIG,RAB23,UFL1,SH3GLB2,HTR2A,CYP2C18,AHSA1,NOPCHAP1,ATRAID,CIMAP1B,AZGP1,LMAN1,BET1,GPX7,NOP58,H2BW1,MIR16-1,SART3,ADCY3,NUBP2,EPHX1,DNAJC1,CDC16,ACAT1,GTF2I,MAGED4B,ICAM3,UQCR11,CSNK2A1,CAV1,SCD5,ANAPC13,PSMA6,UBL5,OXCT1,SERPINI1,ZBTB17,ZNHIT3,ZRANB2,TXNRD2,TRAPPC10,HMGN4,TMEM199,MAPKAPK5,MAP1S,CDC42,VEZT,MBLAC2,ZNF511,SMAD4,THUMPD1,RAB30,APOBEC3C,POU5F1,MIR23A,NOP16,HUWE1,SNAI3,SNX3,MED9,OAZ3,BLOC1S5,TSSK1B,RHOG,NHEJ1,STK11,SLC25A45,RAB2A,MLLT6,GCLC,MAGEB10,UNC45A,KIF3C,ABHD12,GSTK1,RNF146,CIPC,APOBEC3F,CPLX3,PRKACB,PNMA1,UCHL3,CFAP68,TOMM6,MCPH1,CSF2,TNNI3K,PLSCR1,SERPINC1,CDKN2C,HSPB6,TMEM147,PRSS23,CTNNBIP1,CEP15,C2CD2L,ACOT6,RPP21,KIT,WBP11,PLEKHF2,TOB2,PLAAT3,EWSR1,ADIPOQ,SELENOO,H2AX,NRSN1,AR,GJA1,POLA2,YAE1,RBM17,ZDHHC15,CD2AP,MRPS9,EXOSC1,SNX11,SMYD3,AGAP2,KHDC4,PAK5,POLR3GL,NUCKS1,GTPBP8,EGLN2,PARP11,CPNE1,PCSK9,IDH2,ATP8A1,KCNJ11,MS4A7,KLHL12,SENP5,HMX2,GIMAP4,MNS1,RPS3,ELAVL4,STK3,DSN1,PKP4,NSDHL,FOLR1,ALCAM,SF3B5,ORMDL3,POLR2C,MT1M,JUP,AHCYL1,MRPL17,BIRC5,AGA,SYP,STOML3,DNTT,NUDT3,WRAP53,HNRNPA2B1,CLU,ACTN4,PNRC1,RNF144B,SLC25A46,MAGEH1,REXO2,ACAP2,VRK1,LDAH,RBFOX2,SCFD1,ZBTB5,HEY2,TMX4,IRF4,MCM4,DDAH1,NMI,MIR221,RSRC1,EDEM2,HS3ST1,NFE2,SLC35B4,TTC8,HSPE1,NDUFA12,CCDC86,ZMAT2,ZBTB6,MPG,ADRA1A,ACTR1B,MARCHF4,ERCC3,SMNDC1,CYP26A1,AP1G2,CMC4,PSMB3,ABCC5,SUPT4H1,CFL1,TRMT6,SMPD2,HAND2,COX11,SRXN1,TCEANC2,FCGR2A,OLFM2,NLGN1,DCTN4,NEK9,ADRB2,MPC1,SAP18,SEC22B,IL2RG,CITED1,SH3GLB1,POLDIP2,DISC1,USP3,PABPC1L,ARL6IP6,MFAP3L,SNAPC5,INHA,NME4,TCEAL8,HCRT,NSFL1C,TRAF2,HINFP,ATP5PB,MAP4,PGS1,FOXP2,CPLX2,TACR1,PCGF3,MRPL13,FKBP8,PTPN1,TPD52,COX7A1,IVNS1ABP,ANKMY2,ACOX1,ITM2B,NUDT5,VDAC2,MRPL22,HSD17B8,CBFB,ESS2,AKAP14,IDH3A,UBN1,VTI1B,ACTL6A,ACER3,MIR143,RNF20,PIP4K2C,SELENOK,BCAP29,SYNGR2,DNLZ,MIR1304,URM1,ABHD4,HELT,RAP1A,SERPINA1,MRPS21,ECD,USP13,SNRNP40,KCTD10,PPP3CA,SLC25A4,MMP14,IFT52,TRIM15,RFXAP,ATP5F1B,FAU,ZNF174,IFRD2,DELE1,HSP90B1,STK4,UMPS,RPL10A,DTWD1,SMDT1,SDHB,ENC1,AKT2,RGS5,RETN,LACRT,CST3,SLC35G2,NRDE2,RNF5,NUP42,COQ8A,EAF2,LRRC57,BCKDK,TOP2B,SSR1,RPF2,CDK20,HS2ST1,PGAP3,MT1E,ZNF740,OS9,IZUMO4,IGF1R,RAB33B,ETF1,PNO1,ERP29,FGD2,SASH3,NOB1,CCNQ,ANAPC16,CD46,MALSU1,FASTKD5,NFE2L1,TRAPPC6A,HGS,GRIA2,CLSTN3,SRC,LAT2,TFG,DDX23,DIO1,CD1A,PPP5C,PLD3,ZC4H2,WDR12,JAK2,SPMIP9,SLC39A13,ATP6V1G1,SEC23A,KDM4B,ARGLU1,CERS2,PDIA2,GMNN,TMEM11,TRAF3IP3,NDUFA4,RPS10,LMBR1L,GPAA1,RAB27A,CA2,KCNH1,NTF4,SEC13,TMEM209,ZNF805,MIRLET7B,PEDS1,RHOBTB3,SLC25A28,PRKCB,RAB35,CHCHD3,GHITM,POLL,SYN3,CRADD,RAB5C,VIRMA,GPX1,BRAP,ARFGEF1,NKAP,CTNNA2,IGFBP3,PHACTR1,DES,AVL9,RBBP8,SLC35A5,DHRS4,XPO1,LYPLA1,TRAPPC3L,RND3,CMTR2,SRSF1,SORD,COMMD6,ARMCX2,TM4SF20,MMD,CNIH1,STX12,MOV10,COQ8B,AQP11,VPS28,SMAD5,VCPIP1,MIR193A,CAPN1,CSTF2T,PSMB7,SLC35F6,PLAC8,RPAP2,PHYKPL,TRIM5,CASK,SSBP3,CENPL,YES1,TRIM37,CREBBP,FBXL3,ID1,GNB1L,ARL4A,TRMT5,B3GALT4,MIR9-1,KCNF1,SLC22A12,MSMB,TCEAL1,RPS12,CD1E,CMA1,SLC35D1,COX6B1,WDR77,RPL27A,ZFP1,GGH,RNASEK,LMNA,WDR19,TBC1D1,SIN3A,RNF10,CXCR4,FABP7,GNAI3,ZNF322,METTL21A,STX11,BTF3,MRPL50,UCKL1,AGPAT5,HNRNPF,CLK1,BOLA2B,MTRES1,MIR197,LAMB2,ABCB9,NFKBIA,SFTPC,VWF,EEF1G,SFRP4,CLIP3,SATB1,MT1X,SDS,NTMT1,DFFA,FAM118B,MKKS,DMTF1,KIF1C,PDAP1,PLG,H1-10,LIG3,CRB3,ZNF397,ATP6V1A,XAF1,CHST1,SCML2,ITM2A,NDN,FAM156A,PARD6A,PREPL,RIC3,ATP6V1E2,VPS72,COPE,SLC2A1,CDC73,TERT,TMEM59,NCOA5,PSMC5,GPR15,CYB561,ITGAV,CMPK1,ERLIN2,CLPB,CLDN9,CCHCR1,G6PD,KCNIP3,SNRNP70,UBE2V1,FAM169A,ATG101,GFPT1,WASF3,DLG1,LCA5L,LZTFL1,ZNF593,DCUN1D3,CMAS,SOX2,H1-6,TYMS,CTDSP1,SLC25A23,SLC25A24,H2AZ2,MATR3,GLYATL3,ZCCHC9,DAG1,ABHD5,FKBP1B,RPL31,GPR137,SNAP25,SETD7,SS18,COX7B2,WDR11,SIGMAR1,ALOX5AP,PRKCA,OSTM1,FOXJ3,NSMCE3,CHRDL1,BCL2L1,SLC11A2,ZNF592,RPL24,CDC42EP2,CAMK1,MGP,IL1B,DNASE1L1,BCL7C,FKRP,FMO3,RRAGA,SLC35C1,MAGED2,CRABP2,ZNF688,BPNT2,SYNE4,RPL18,ATP2C1,SAMHD1,ACO1,MTDH,ELK3,MIR422A,CDH11,ANKRA2,PIH1D1,INPP5K,PYGB,NAPG,RAB39B,CSTA,CENPW,MORF4L1,CCNI,MYG1,NFYB,SLC22A8,ST3GAL1,PDE2A,ZBTB14,ATP6V0B,SQSTM1,ATL1,PPM1G,PHF21A,GSK3A,ZNF526,TAF9,TFCP2,SLC25A21,CLTRN,POGK,BCL9,MRPS16,DCK,BMPR2,SCG2,EEF1AKMT3,PHF23,ARMC7,POLR2B,MTG2,TMA16,SP2,CRBN,HEBP2,CBR3,NFKBIL1,FTSJ3,H2BC17,CYB561D2,SPCS3,PMPCA,OSR2,PEBP1,PHB2,GLT8D1,ZNF787,SLC16A1,AIF1L,AATF,AMT,MAPK10,HNRNPAB,MIR106A,IRF3,RPL3,GTF3C3,VAMP7,SAP30BP,GRIK1,STARD13,B4GALT4,RFX5,THOC6,USP6NL,FOS,HEXIM1,TOPBP1,RDH10,ABCE1,MGARP,PSMB4,CCDC186,UNC119B,LRIF1,TMEM39A,TNKS2,BACE1,POLD4,IRAK4,MIR208A,NCKAP1,FERMT2,RAP1B,TOR3A,SMAD9,CHPF2,RUVBL1,SERINC1,FBXW11,CHTOP,MTRF1,C2CD2,GABARAPL1,FUT8,SYNGR3,COMT,ZNF451,CDKN2D,TIGD7,OLA1,PDF,RBM3,CDKL2,PGAP4,TCP1,MOXD1,LST1,NRM,MDC1,LRRC8D,PHF13,ELOVL3,REEP6,CAB39,PABPC1,NEDD8,TNRC6C,DRG1,THBD,RADX,TMT1A,PIGW,CDC23,RSAD2,SEC11A,LDHB,METTL15,MRPS18C,DERL2,ACSS2,RAB6A,TRIM22,S100A6,MRPL33,RAB32,CACNG3,PSMD1,GMPPA,FGF13,EMC1,HSH2D,MGAT5B,ATP5F1A,SCPEP1,RAB11B,ROPN1B,UBE3A,POLR3B,SNRPA1,REEP4,FOXP1,KIN,HOXD12,PICK1,SKAP2,COX7B,SRP14,CCNB1,TRAF6,MTHFD2L,CHST10,TGFB3,RPN1,DXO,SMUG1,TMEM190,RPS26,FAM222B,HSD17B6,SUCLG2,QPCTL,ABCB1,BOLA3,PLSCR3,NDUFAF4,GADD45G,FGF1,PTGDS,IER3,MRPS18B,THAP1,FAM193B,SRSF8,COX20,RIOK2,TMEM160,CNPPD1,SGTA,DTL,IK,EIF1AD,CREB1,CINP,ADRM1,GDPD3,DERL1,MND1,FGL2,USP39,GAPDH,ANGPT1,B3GALT2,IDE,TAPT1,RRP7A,TAF5L,IRF2BP1,ANGPTL2,PCYT1B,RPL27,CRLF3,SEC22C,LGALS8,JAML,CCAR2,RBM42,LIPA,ATP5F1E,JADE1,STIM1,SPTSSB,MIF,TMEM168,SUPT7L,PPP1CC,JUNB,HNF1B,CDC7,SRARP,FAF2,NAA15,H2AC7,LSM4,FMC1,SNX24,MYBL2,DHX38,MIR1234,SEC61A1,VPS26A,PPP1R26,UTP23,EGLN3,APOBEC3H,SLC31A1,RPSA,NKX6-2,DYRK1B,VPS26B,TRIM23,UBE2L3,RUSC2,TERC,FCN2,SCNM1,AMELX,PSMC3,TAGLN3,HIRA,RHOJ,ZKSCAN1,RPL37A,MTM1,NDUFA2,STK38,IKZF2,SSBP4,ELOF1,TIMM17A,SSH3,PKIB,NEK7,HYAL2,MPHOSPH6,STAU1,ASRGL1,HMGA1,KLHL15,RGS6,TP53,TOM1,SUMO2,SSR3,SLA2,DHRS7,CTSC,RPL23A,MPDU1,PGAM1,EPCAM,ASCC1,CASP4,MORC4,SIGLEC5,GJB1,VPS26C,H2AC13,WDR6,DDR1,TMEM45B,ISCU,H3C1,MIR99A,UBASH3B,FBXO7,IQSEC1,CDC37L1,SNAPIN,RINT1,UTP25,VEGFC,IRF7,SC5D,ASIC1,MCL1,SRSF4,CXXC1,ATG9A,SNAP23,CERS6,CTNNB1,MPV17,TXNRD1,MT2A,GPX4,ZNF32,SNAPC2,SPC24,APEX2,ESD,SYNJ2BP,CCDC85B,RETREG2,MOSPD1,AP2M1,CSRNP1,E2F4,PPFIA2,IFT172,POLR2F,PATE4,PCCB,SDR16C5,APBB3,COX17,ZC3H14,CLP1,LRRC8C,HMGB1,SYT4,RPS15,FMO1,LURAP1,BAD,BARX2,MGST2,JPT2,EIF4E,RANBP6,CNOT6L,SETD4,RPA3,MAD2L1BP,HBEGF,TMSB4X,SKIC8,GPRASP2,SSNA1,PLAA,TENT5C,TRIM6,CCDC106,FBXL19,SELENON,GLE1,YIPF3,TBC1D4,TECR,TLCD4,PSMB11,PYDC2,STARD3NL,BPGM,NDFIP1,TSSC4,PTS,CD3G,MME,MBD5,IREB2,NIF3L1,OSGEP,MTMR12,SNX1,ELP3,TMX3,POLR1D,RBBP7,MIA2,E2F6,NUP50,ZNF507,TCF21,BTBD10,PPIH,PEX5L,HS3ST3A1,PPT1,COMMD3,TCEA1,MARCHF5,CNP,ANAPC15,RALYL,POLR3H,XPO5,AP5S1,RIMOC1,CTLA4,CHMP5,RNF26,STAC3,MVD,CLIC4,KLC2,CMTM6,ZNF200,HACD4,SSBP1,DPPA2,PPM1D,LILRB4,ATPAF2,MPIG6B,THOC3,CD63,SLC25A26,CLCA1,SEC61B,MACROD1,SVIP,ABHD16B,TFDP2,SESN2,TRIM24,GPX3,FZR1,TBC1D16,PSMD6,DHRS4L1,CDK1,ZNF304,MTAP,SNAPC3,UQCRQ,GIT2,MIR194-1,RPS29,PIGK,YIPF5,ZNF609,SLC25A3,KLF3,THOC1,ZNF267,GJC1,PAOX,HDHD3,CSGALNACT2,AKR7A2,CCND3,EIF3E,SOX14,FZD6,USP30,DCP2,DKC1,TMEM231,ZBTB26,RING1,ACTR3B,SUFU,TMED9,RPA2,GSTCD,APOBEC3B,SAYSD1,TESPA1,SGF29,SLC25A14,CYGB,VAMP8,ODAM,PLN,MGST3,API5,WBP2,TBK1,THAP2,FBXO11,VASH1,ORMDL1,NUDT19,MED27,MCMBP,GNAQ,TCOF1,RPS14,RPS9,PNPLA4,MED4,LMO3,VSTM2A,KRT8,PDYN,ACKR3,NME1,MED30,BORCS5,MXI1,CYFIP2,COL3A1,BECN1,PDCD4,SLC18B1,RPL35,NUP62,PRPF4,MPV17L2,IRF1,YBEY,STK16,MAMDC2,SOD1,DGCR6L,FOXP3,ZMYND11,RCE1,JCHAIN,RNF8,RBMX2,GLO1,TIMM8A,MYT1L,PLCB2,GDI2,MYD88,FERD3L,HTRA1,TMEM30A,ZNF596,PIR,SLC16A10,PRPF18,GZMK,CDK6,PHF12,DAAM1,SLC35F1,MRPS23,MORC2,RGS19,SLC22A6,SEMA5A,ELOVL6,TOR4A,MIR145,GTF2E1,CYP2C9,CLCN6,DNM2,SERTAD1,ARF6,CABCOCO1,GABRA1,PPP1R8,SLPI,PPTC7,ACTB,ASF1A,PYROXD2,DAPK1,UBIAD1,ZNF24,UBE2K,DHRS3,MEPCE,THAP7,TRIM34,NDST1,RACGAP1,GK5,SEMG2,STAT1,ETV6,RGS10,PFDN2,MRPL51,FSTL1,F10,CRTC2,CRYL1,SERINC3,PSMA4,COX16,MAEA,KPNA1,UQCC2,CGAS,PLA2G4B,SKP1,DHRS1,ETFBKMT,LDHAL6B,NR0B1,RPL23,SRPRB,GCFC2,HSPB1,PITHD1,MTPN,SYNDIG1,HP,RPGRIP1L,GNA14,PCDHB13,TIMM13,SLC35E1,TULP3,BORCS6,POLR1B,UQCC3,CCNA2,SRP72,PRIM2,YKT6,CDC20,LYZL6,WDR82,HACD2,CCSAP,SLC51A,SLC22A17,PRL,SPINDOC,EZH2,FOXP4,PGK1,SDCBP,AIF1,GSTT1,DCAF16,LBH,IFIH1,ATP6V1G2,MTMR6,ERO1A,CAND1,TREML1,FURIN,GTF2H5,HSP90AB1,TFE3,RARRES2,MTERF2,SLC6A4,HSCB,CCNF,RBP5,MIR30B,RGCC,RTCB,GSKIP,SRD5A3,TAS2R16,HR,VAPB,PACRG,MED22,SLC25A10,TRIM35,WDR44,PSMD14,RBM5,DYRK1A,TMEM14B,TLR2,CD274,DLST,PRCC,RPRD1A,EVA1A,RAB3B,CLXN,JKAMP,CYP2C8,SOX21,B3GNT2,RAB40AL,TES,CARTPT,PRDX4,MYRF,TNFSF10,BLVRA,NOA1,OARD1,CHP1,H1-5,TIMM29,PPARG,BHLHE40,IFRD1,CCDC181,MED10,CLRN1,BOK,UBE2D1,GFUS,VMO1,UQCRH,TRAM2,ICA1,F9,GFM1,ALKBH4,MRPL11,SELL,RDH11,SCML1,RPAIN,CLN8,ABCF1,FAHD1,ALG11,MRPL53,CYP2D6,LAMTOR3,CAPN2,RBM7,RAB14,DSTN,NR2F6,ATXN1L,GPC1,DNAJC2,NDUFS6,FUNDC2,ZNF790,GCHFR,TSEN34,SERTAD2,NDST3,DDIT3,CIMIP1,CD2,UBXN6,CIART,OPRM1,ADH1A,CD79B,NSG1,FTL,AGTRAP,SLU7,SLC35E4,CD2BP2,SLC25A32,RNF113A,RC3H2,TP53INP2,MYL12A,SFTPA1,GOSR2,DNAJC7,CCDC65,SGIP1,RMI1,MEF2A,SARM1,FABP12,HCFC2,TUBG1,CYB5R4,DCTN3,EFNB1,ZNF436,PSMG2,FYTTD1,HDAC11,CSNK1A1L,BET1L,HNMT,GTF2A1,PAX9,NEUROD2,RERE,ZBTB45,PDHB,SLC25A44,SYCE3,RPS5,KLK3,RPS17,NUDT9,TIMP3,IL12A,ZNF652,PSKH1,NUS1,LAMTOR1,PEG10,GALC,RBM22,NDUFS2,GLRX5,MGME1,TAX1BP1,NUP153,PRDM4,EMG1,TIMM23,CSH1,HOXB1,CDAN1,FUNDC1,HRAS,POMT2,AVPR1B,SUMO1,ARL15,CHST2,MCOLN1,CHMP2A,VGLL2,RAB9A,HTRA2,SERPINB10,STX1A,YPEL5,SFT2D2,TVP23B,DYNC1I2,PGRMC1,HNRNPL,RPS6KA4,URAD,CNOT2,TMEM123,BUD23,STAP1,ACSL4,SCAMP5,THG1L,NQO1,PDSS2,MT1A,ADK,TEX19,ARF1,GNB1,WDR37,CCR5,APH1A,SLC20A2,UHMK1,LGI3,FUT1,NAB2,CDK9,ACACA,IFT25,AGK,MAF1,GPC4,H2AC6,STARD4,CAPG,CYTH1,PRDX1,UGP2,SF3B4,PMM2,METTL6,SETD3,KXD1,LYZL4,APOBEC3A,C1D,CBL,DBT,LYZ,CD1D,CISD1,RABAC1,DNTTIP1,MYCT1,PRPF31,TRIB1,PPIC,COP1,OCRL,WNT7A,TBC1D5,CRISP1,POR,UGT1A1,MYL12B,CYBC1,MIR15A,CNOT7,BFAR,KMT5B,TRIM3,PTRH2,SPRED2,GTDC1,SELENOF,CREB3,PDE7A,RCHY1,SLC4A8,LDB1,DNAL4,INPP5E,CNOT6,CCR7,BANF1,TRA2B,BCCIP,PIGC,NKIRAS1,B2M,CHMP1B,SPTAN1,ISG15,RLIM,ZBTB16,ACHE,LTBR,MREG,EIF5A2,CCR2,RUVBL2,SIAH2,KGD4,CST11,SYVN1,PROX1,ATP5PF,RPP25L,FLCN,NEU1,ARG2,TFB1M,MRPS26,TWIST2,DPEP3,FXN,GABBR1,FBXO22,SAMM50,CEP85,EHBP1,UBE2E2,HFE,SNRPE,WDR83,CX3CR1,EI24,AMACR,JPH4,GPM6A,PGM1,MYO6,CDKN2AIP,EYA3,TEDC2,RHCG,FAM53B,AGER,MSX2,RFC4,QRSL1,FOXN2,GNG5,SYT2,HSP90AA1,CLBA1,ID4,UGCG,CTNNBL1,MXD1,ZDHHC8,G6PC3,VAC14,MBL2,CYP4F8,RAB1A,PSENEN,GFM2,YTHDF2,ANKRD50,AP3S2,CTTNBP2,RERG,ACADSB,MARCHF3,NEUROD6,IKZF5,NDUFB5,COL1A2,HDAC5,ALB,EID2,EMX2,AUH,TIMM10,GTF3C4,DNAJB4,TSNAX,SPMIP8,GNB4,OVGP1,REG1B,TRNP1,RAB19,TIRAP,GTF2H2,AFTPH,ZNF263,CFAP91,RAD23B,CRYGB,PAPOLA,SYBU,LCORL,OLFM3,BTG1,BTG3,ERRFI1,GABRB3,PPP1R11,TM9SF1,PTEN,ZNF473,PPP1R12A,CDK17,CIMIP2C,ABHD8,RNF152,UBB,PTPN11,AGR2,ANAPC11,TPPP2,CWC15,CHAMP1,MLF1,IL15RA,EMP2,MIOS,G0S2,CCN3,DPY30,ADRB1,RMND1,TUSC3,RNASE6,PYM1,SLC1A2,SMAD1 |
| 2.350e-11 | -24.47 | LONP1 (lon peptidase 1, mitochondrial) | protein interactions | 9361 | 458 | 194 | 19454 | 5460 |
MED10,RHOB,DCAF4,HSP90AA1,PFDN2,RIT1,ILK,MTG2,AUH,PMPCA,PYCR1,MRM2,MRPL23,NDUFAF4,KLF3,ATP5PO,ARMCX3,NDUFA5,RND2,PPP2R2C,COIL,NT5C3A,DNAJC3,EXD2,PSMA3,RHOG,MRPS26,CLPX,STOML2,MRPS35,ATG7,NDUFS8,PHB1,ATP6V1A,GATD3,CYP2C8,NDUFS6,RAF1,HSDL2,E2F4,EMC8,MRPS17,HSPD1,NUDT5,MKLN1,HINT2,COX8A,NRP1,PNPLA4,PYCR2,DEPDC1B,HMOX2,SLC25A4,RHOJ,VIRMA,ACAT1,MRPS34,LMNA,MET,PCK2,COQ8B,PSMC4,ARHGAP1,SPMIP6,FBXW7,MRPL20,POLDIP2,RPA3,MME,RHOU,SIRT7,SLC2A1,POR,GRSF1,LAMTOR2,EMC4,SLC25A46,ATP5MG,PCED1A,ARF6,PRNP,MRPL50,ATP5PD,SLC25A12,MRPS23,HDHD3,NDUFS3,NDUFA2,AURKAIP1,BCS1L,HSPE1,FASTKD5,ABHD10,SFXN1,HAPSTR1,HSD17B10,IGF1R,EMC2,CCT2,LAMTOR1,MRPS25,MYC,KLHDC8A,ATG101,HMGCS1,BTF3,ATP5F1B,ESR2,TACO1,DLST,CCDC90B,MTG1,UBAC2,PIH1D1,NDUFAF3,MRPL12,NDUFS2,EMC1,ADRB2,PHB2,MRPS7,HSPA8,SF3B1,DCAF5,PEX3,ARMC8,DCAF4L2,NDUFV2,TCP1,RHOH,UQCRH,PNPLA8,CCT7,TNIK,CORO1C,PDHA1,RND3,NDUFA12,RHOBTB1,TOP3B,CFAP68,ETFB,HEXA,SOX2,EEF2,KRAS,KGD4,PAK6,FBXO11,RC3H2,UHMK1,UBE2H,RAB2A,SPMIP8,NDUFAF2,CFL2,RPGRIP1L,ROCK1,UQCRC2,MRPS28,PSMC5,RPRD1B,QRSL1,SAMM50,CYC1,HOXB8,MRPL10,CDC42,NME4,PML,GFM1,TUBG1,DPP4,USP2,COX5A,LYPLAL1,RPS27L,ESD,COQ8A,MRPS9,SSBP1,COX4I1,RAC2,DCAF12L2,FURIN,CCDC69,ATP5PB,PDE12,MRPS33,RASL10B,ATP5PF,MRPS18B,RAB13,CLPB |
| 2.358e-11 | -24.47 | RPL37A (ribosomal protein L37a) | protein interactions | 6168 | 367 | 162 | 19454 | 5460 |
NOP58,RPS10,RPL7,LYAR,RPLP1,RPLP2,RPL8,RPL9,PHB1,MRTO4,NKX3-1,MYEF2,RB1CC1,RPL23,DRG1,AGR2,ATG7,MAP3K14,DDRGK1,RPL6,WWP2,RPS4X,RPS27A,RPL28,AHCYL1,RERE,KRAS,SETD4,RPS24,RPL31,SLC25A5,PABPC1,PPAN,RPS11,SART3,RPS23,RPL18,EZH2,CHMP4C,RPL29,RPS7,B3GNT2,LRIF1,RPL19,RPL10,RPL35,RPF1,RPL7L1,RPS9,ZNF22,RPS26,RPS5,RIT1,H1-1,NSA2,FYTTD1,BRCA1,FTSJ3,RPL39,BTF3,KANSL3,MYC,CUL3,UFL1,STAU1,NOP53,RAB5A,RPS28,EMC9,H1-5,RPL27A,MDM2,DKC1,RBM42,SURF6,CAND1,DNAJC1,RPS16,FZR1,RPS27L,FAM199X,RPL12,RPL32,RCHY1,CDK12,RPS2,RPL10A,USP15,EID1,RPL24,MPHOSPH10,SNRNP70,COPS5,ENY2,MICB,MEPCE,RPS13,RPL17,PAK1IP1,VRK1,IMP4,RPL3,RPL23A,DHX9,NKRF,SRP72,LLPH,RBM34,DNAJC2,RPL15,UBL4A,FBP1,TP53,RPSA,RSL24D1,DEK,RPL22,NDN,BUB3,RPL13A,RPL10L,PRKRA,FGFBP1,EIF2S2,RPS20,RPS12,CCNF,RPS3,EIF4A3,METAP2,IGF2BP1,UBE2H,RC3H2,RPS17,RPL26,FBXO7,PPP1CC,TUFM,RPF2,AKT3,RPL7A,UTP23,CXXC1,BRIX1,RPS15,NPM3,FBXW7,RPL4,EXOSC4,RNF113A,SQSTM1,RPA3,RPL27,BAP1,RPLP0,RPL26L1,MACROH2A2,ZNF770,RPA2,H2AC7,CFTR,RPS14 |
| 2.392e-11 | -24.46 | PRDX5 (peroxiredoxin 5) | protein interactions | 25824 | 158 | 84 | 19454 | 5460 |
TMEM205,GLRX5,RAF1,MSRB3,RAD23B,FAM136A,SOD2,NME1,CHMP4C,UBE2B,GINS4,VAMP2,NUDT19,HINT1,MAP1B,DUSP19,SAR1B,MX2,UBE2A,GUK1,NEDD8,GAPDH,CTNNB1,BABAM1,PRDX1,CBL,AGR2,AK2,NME2,GATD3,IGBP1,DSTN,AIFM1,SLAIN2,PPIA,MPP1,GABARAPL2,DET1,SPR,SUMO1,CCND1,SHOC2,NUFIP2,PSRC1,PPT1,ACAA2,ADSS2,PRDX6,CLK1,COX17,ARHGEF6,PEBP1,BAP1,SOD1,PTRHD1,GPC1,FBXW7,SMCP,HSCB,TOMM40,CFL1,ANAPC15,CFL2,AK3,LDHB,CDKN2D,RAB11A,ACO2,MDH1,FXN,UBE2H,ICAM1,ACAT1,RPS12,TRIM24,ENO1,CCDC90B,CCNF,LGALS3,TXNDC12,TXN,PRDX2,CTSB,LDHA |
| 2.564e-11 | -24.39 | RPL31 (ribosomal protein L31) | protein interactions | 6160 | 646 | 258 | 19454 | 5460 |
RPL3,DHX9,SNIP1,MEPCE,RPL17,NEDD8,H3C1,IMP4,WBP11,UBL4A,SRFBP1,STRBP,IMP3,NAA35,MTCH2,RPSA,TP53,TFCP2,RP9,IK,RBM34,DKC1,RBM42,SURF6,RPS16,CAND1,FZR1,RPS27L,COPS5,CD81,CSNK2A1,ENY2,CMSS1,ZNF24,NOL12,RPS2,RPL10A,USP15,TUBG1,SNRNP70,RPL24,RNF113A,BAP1,RPL27,HSPA5,RPS15,WDR3,CFTR,E2F6,HEXIM1,ZNF770,RPA2,VPS4B,SRP54,PSPC1,RPS3,LIG3,SMURF1,SRPK2,RSL24D1,RPL10L,RPS17,ZSCAN25,RPF2,RPL7A,UBE2H,RRP7A,RC3H2,EWSR1,TOP2B,RPS4X,H1-6,KRAS,H1-3,EEF2,MSX2,RPS7,TRMT1L,SUPT5H,ZRANB2,CRKL,RPS23,RPL18,EED,PSME2,ISG20L2,RPS10,LYAR,CTNNB1,NGDN,BTF3L4,DDRGK1,DDX50,RPL6,WWP2,PTDSS1,POU5F1,DRG1,AGR2,HSPA8,SF3B1,DDX5,SLU7,NGRN,RPS28,UFL1,STAU1,RPL27A,EIF4B,PIH1D1,ADSS2,MRPL13,GTF2F1,GTF2F2,RPL10,KBTBD6,BTF3,MYC,HNRNPAB,HNRNPC,ICAM1,RPS26,NSA2,FTSJ3,ATG3,H1-10,RPL23A,TCOF1,NKRF,RPS13,PAK1IP1,VRK1,NOC4L,EEF1A1,APOBEC3D,FCF1,RPL15,FBP1,CCDC47,ILF2,SRP72,LLPH,PRR3,RPL12,SRPRA,ARL10,KRR1,MDM2,CDK9,RPL35A,TOP1,HDAC6,APOBEC3F,MOV10,EMC4,SPATS2L,BRD3,TCEAL9,KIAA1143,MPHOSPH10,KIN,PPM1G,RPA3,HELLS,UTP23,AATF,BRIX1,NPM3,HMGB1,FBXW7,RPL4,EDF1,RPS14,TPT1,RPL26L1,RPLP0,ZNF574,METTL14,PRKRA,RPS20,PTEN,RPS12,CCNF,METAP2,EIF4A3,VIRMA,RPL22,RPL13A,RPL26,PPP1CC,TUFM,RPS24,SLC25A5,RPS27A,MRPS17,SAR1B,DHX16,EMC8,G3BP1,ETFA,TRIM37,MAK16,RPL29,B3GNT2,FEN1,RPS11,EZH2,CHMP4C,XPO5,RPLP1,RPLP2,RPL8,RPL9,FOLR1,MRTO4,PHB1,IFIT2,DHX15,NOP58,RPL7,BUD31,ATG7,AHSA1,RSBN1L,RPL23,TXNL1,CCDC86,UPF3B,NKAPD1,COIL,G3BP2,RADX,NOP53,YTHDF1,H1-5,MFAP1,EMC9,ADNP,RPL37A,SEC61B,RPS9,ZMAT2,RPL19,RPL7L1,RPF1,RPL35,MRPL16,ZNF668,PRPF31,ACO2,CUL3,CUL2,NOP16,RPS5,RIT1,BRCA1,ZCRB1,YWHAZ |
| 2.611e-11 | -24.37 | RARS1 (arginyl-tRNA synthetase 1) | protein interactions | 5917 | 320 | 145 | 19454 | 5460 |
CARS1,ATP5F1A,RUNX1,USP14,GORASP2,MIR145,NCKIPSD,CDC73,UBE2H,CCNF,OPTN,PSPC1,MIR16-1,NECTIN2,VIRMA,MIR34B,ATG16L1,EEF1E1,CDC42,MIR1-2,CFTR,SDCBP,RPA2,GRM2,FGFR1,HEXIM1,RPLP0,UBE2M,MIR21,MIR7-1,RPA3,BAP1,MIR10B,MIR205,MIRLET7I,RNF113A,DLAT,MIR34C,NF2,MIR7-3,FBXW7,MARS1,MIR29A,MIR107,HSPA5,KARS1,HDAC6,GAPDH,POR,MAP4,MIR34A,MIR106B,MIR25,PLEKHF2,RPS16,MIRLET7G,MIR429,MDM2,TMPO,COMTD1,MIR15A,MIR200C,MIR17,MIR20A,CBX3,RAB1A,MIR200A,MAP1B,METTL18,MIR9-3,DHX9,MIRLET7C,MIR16-2,MYC,CUL3,MIR98,BRCA1,PSMD14,MIR363,RIT1,LMBR1L,RAN,AP2M1,MIRLET7B,TUBB,TAX1BP1,MIRLET7D,ESR2,APEX1,PRDX3,KCTD12,EMC9,HEXB,PIH1D1,HSPA8,CRY1,HDAC5,UFL1,STAU1,MIR106A,G3BP2,GSTM3,WWP2,MIR143,MIR29C,ATG7,CTNNB1,DDRGK1,SKIC8,MIR31,AGR2,MIR1-1,MIR221,HSPB1,MIR140,MIR7-2,PHB1,MIR214,MIR141,HNRNPL,MIR9-1,SUMO2,CCAR2,DHX15,TOP3B,RAF1,B3GNT2,SOX2,ISG15,EEF2,EZH2,CHMP4C,NME1,PDHA1,MOB3C,HSPD1,CCT8,PABPC1,MIR9-2,MIR206,EMC8,G3BP1,KRAS,MIR155,TFG |
| 2.658e-11 | -24.35 | Formation of a pool of free 40S subunits | REACTOME pathways | R-HSA-72689 | 105 | 66 | 10285 | 3229 |
RPL17,RPS3,EIF3G,RPL22,EIF3E,RPL19,RPL26L1,RPL10,RPL35,RPL12,EIF3J,EIF3D,RPL9,RPL31,RPL18,RPS11,RPS23,RPS12,RPL27,RPS2,RPL4,UBA52,RPL7,RPS9,RPL37A,RPL29,RPL10A,RPS15,RPL23,RPL39,RPS10,RPL26,RPS7,RPS27L,RPL24,RPL35A,RPS14,RPL23A,RPL7A,EIF3K,RPL28,RPS20,RPL6,RPSA,RPL3,FAU,RPL32,RPS24,RPS16,RPL13A,RPS29,RPLP0,RPLP1,RPS4X,RPL27A,RPS27A,RPS13,RPL10L,RPL8,RPS5,RPLP2,RPS17,EIF1AX,RPS28,RPS26,RPL15 |
| 2.666e-11 | -24.35 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4189 | 1372 | 16828 | 4835 |
CSE1L,UBE2B,FBXO3,AGAP2,NEK9,CDK5RAP3,FURIN,TNFSF10,FAM3A,RNF146,SAP30L,CIRBP,TSSK1B,PHKG1,PICK1,NTRK3,NEK7,NSDHL,MED13L,EXOC2,XPO1,IDH3A,RFC5,THRAP3,RNF103,XPO5,POU3F4,APOBEC3C,YES1,LDHA,VAC14,GAPDH,GSK3A,UBL4A,HDAC5,HECTD3,FATE1,DNAL4,CXCR1,NEDD8,MRAS,MDH1,ELK1,RAB28,MMP14,RAB6B,RASGRP2,ST13,FBXO30,WWP2,RAP1A,CDKL2,GAS8,LMBR1L,CBL,KCNK17,COPS4,TSPAN7,HSPE1,PIK3R1,SERPINH1,RAB4A,DHX16,DCLRE1C,SUMO1,LHFPL1,HSPB1,POLD2,KDM2A,XPOT,CXCL1,ITGA2,COX6B1,SRSF1,NLE1,EPHA2,MAPRE2,CDK6,TAF2,NCSTN,SGMS2,SLC38A2,P2RY10,SMURF1,FKBP4,PSKH1,SOCS2,UBE2N,CTNNB1,RAB8B,PROX1,CX3CL1,FGF13,PRKX,LSM6,PEBP1,NAB1,IL5,CERK,USP39,USP38,CBX7,NFE2L2,RAD1,GNAQ,SPRED1,PITPNB,NONO,POLL,SMAD2,USP46,SNX3,SIKE1,NCOA5,IGF2BP1,RUVBL2,TNFAIP3,RAP2B,MTMR12,DUOXA2,TRAF7,CDC5L,SIRT7,RABIF,ETV6,DEK,PRKD3,NUP107,RNF152,EGLN2,CDKN3,BPGM,DUSP9,AKR1A1,RBPJ,CXCL9,FBXL3,INPPL1,ASB1,RGS10,KIF2A,NKRF,MCPH1,SLC35A2,ID1,CYC1,POU1F1,NR0B1,SPOP,CASP4,COX7A1,FBXO9,SASH3,CCND1,KLF10,DIRAS1,ARHGAP21,RHCG,MCM6,ITM2A,BMPR1A,ADH1A,DMAP1,MTAP,RAB3C,TNFRSF9,BATF,DUSP1,NFYA,PPP1CC,IFT57,ACVR1,ANP32B,BCL2L1,DCAF8L2,ALKBH2,KLK9,NCKIPSD,DOK4,ARHGAP1,RNF141,NFE2,TRIM32,PRIM2,CD99L2,FBP2,ZMPSTE24,MAP3K12,ZDHHC15,RSPH1,E2F6,RPS4X,SOX3,TRIM3,PGM1,IKZF2,LIG3,PRKCQ,DKK3,TRIM8,RAB11A,HRAS,ASMT,L1CAM,AKT1,FGD2,IKBKB,AK2,SOCS5,WDR83,MDM2,MRPL13,PFDN5,COX10,CDK8,CNP,RND3,TFG,GNAI3,SFN,RAG1,RING1,ENY2,KLK3,SLC30A5,SMARCD3,MRPL50,PPP1R2,CTNNBL1,IDH3B,TIAM1,SENP5,TRIM63,JAKMIP1,ITK,SWAP70,MYL12A,TRIM46,DNAJC1,MAD2L1,MAP2K6,CDK5R1,RASGEF1C,LMO4,CLU,ANAPC11,CCR6,FOXP3,LDLR,XAGE5,PPP5C,APOBEC3A,ID4,SOCS4,ARMCX1,UBE2A,UBE2D3,CXCL11,GHR,CCT2,SLC6A8,TRIM23,CUL2,IRF1,PYCARD,GNB1,CASK,CDC16,LTBR,ASB8,INPP5E,ZMYM2,CFL2,SNX5,MMP9,BUB3,EXT1,VRK1,JUP,PGK1,DNAJC5,CSNK2A1,KPNA1,CTNNBIP1,GNG7,TMEM74,PLP1,RNF41,LMNA,PHF1,KIT,RS1,BAG2,JAK1,MLF1,ZBTB33,RAB3B,GRAP,DLAT,FZD4,FBXO42,MCM8,SERPINB10,FRMD8,USP2,ADRB1,ZDHHC14,HEY2,RABL2B,FAM199X,ARHGEF6,PTTG1,PTPN1,HECW1,TRIM37,SEC63,RBBP7,NOVA1,RMND5B,ARMCX2,TRIM21,CAMK1,SNX2,C1GALT1C1,EIF2AK2,TRIM27,COPS2,FBXO32,ANAPC2,AGK,ARMCX5,RAB31,DRP2,DYRK1A,RAB18,FKBP14,INSM2,IDH2,AGER,SRP54,PCK2,CAMK2G,CIB3,ACO1,SATB1,SCFD1,SHC1,FGFR1,PPP3CA,NME2,STAU1,PLA2G12A,TSN,SERINC3,KLK6,DNAJC3,BCL10,NOS1AP,DNAJB2,PDHA1,DUSP19,NME1,PPP4C,RGS2,PFDN4,NPR2,CDK4,RAB30,TRAF2,BRCA1,NFKBIB,RAC2,MMP21,STK24,RNF121,LRP6,PGAM1,PTPN22,SOCS3,FOLR2,DERL1,RFC2,SNX18,SOX2,LNX2,CSNK1A1L,PAX9,ACTB,CNTN1,GNB4,PRKAB1,FCHSD2,MOSPD1,EFNB1,RNF113A,PIR,UBE2M,UBE2E3,TRIM10,TFE3,ITGA6,CSNK1A1,RAB22A,AK5,UBE2V2,SMC4,FZR1,SMAD4,PPP2R3A,BAK1,FAIM,CD274,ELK4,SMARCA5,DRAM1,DDX39A,IGBP1,AKAP12,RNF126,FOXP4,LDHB,CDKN2C,ITGAV,COX4I2,MXI1,USP5,EIF4E,TRIM5,NUP37,PPP1R12A,HSCB,TFEB,EED,CIB2,TRIM24,ACSL4,DNTT,GOLGA5,OSBP,BECN1,LMNB1,SSRP1,MED21,HSPA8,VMP1,BCL7B,DNAJC22,ARHGAP25,APOO,SNX17,TOP1,TNFSF13,PGPEP1,F9,CXCL12,PPM1D,IDO1,SERPINI1,IPO8,HMG20A,CCR2,DSTYK,GNG5,FUNDC2,CSRNP1,PADI2,SYP,ATG4A,SFRP4,GPHN,POLE4,HSP90AB1,PIP5K1A,ERH,UHMK1,PTGER4,TRAF3IP2,METTL2A,NLRP6,AKAP14,CHRDL1,FAM162A,CCNB1,SRC,IDH1,GNG13,SAT1,RASL10A,GNG2,TERT,PIK3R3,GTF2H2,MAP3K11,MORC4,KDM4B,GIT2,NKIRAS1,RUVBL1,RAB3D,ICAM3,CREBBP,PDCD4,LDOC1,RGS19,RCE1,TRIM54,RASGRP3,CDC42EP3,MCM3,RAB33B,YWHAB,PLEKHA8,NUS1,MMADHC,APLN,TMEM164,SESN2,DAPK1,KLHL15,ZCCHC12,RABL3,UPF3B,NFYB,PPP1CB,NUP153,OTUD6A,COPS7A,RNF20,DDX42,PPP1R16A,ADAMTS1,CXCL14,RRAS2,BNIP3L,RERG,ASB3,RNF122,BTG1,SERPINA5,ZMYM4,BICD2,GNA14,CXCR6,TSC22D3,USP14,RAN,PGR,CXCR4,HSPA14,PAFAH1B2,ANAPC13,HDAC6,RNF39,PPID,RPN1,ZNF507,STAT1,PAX6,FANCG,APOBEC3D,HNRNPK,PRKAG1,RAB5A,PC,NFKB1,NEK2,F10,MAFG,TMEM31,FOS,DYRK2,DYNLT3,EGLN3,RPL26,RIOK2,RAB14,TNFSF18,TOB2,RNF167,RAB33A,CDK5,GNG3,RNF26,RAB13,RNASEL,UTP23,WWP1,RHOJ,CBLN4,PKIG,JUN,CCR3,OGG1,SUMO3,OPHN1,PPFIBP1,PTGER1,RAB23,DNAJC10,RAF1,STK38,PRRG1,WEE2,RAB5C,PNP,RNF14,PCDH19,DET1,RAB37,SCYL2,PHKA1,FBXO25,TIMP1,UBE2F,FOXP2,IL6ST,CYTH1,EIF4A3,DDX5,PPP2R1A,RAP2C,SMAD3,RPS27L,TESK2,DYRK1B,STK11,WIF1,TP53INP2,SNX24,STAT6,LAMTOR3,EZH2,FKBP10,INPP4A,RAB9B,FUT1,BAP1,RPRM,ARL4A,LITAF,CCNF,WDR44,RAB2A,CTNNA1,MEF2C,TCEAL7,RHOB,MAX,PCGF3,TRIM11,PROM1,TOPBP1,G2E3,E2F4,PPM1G,CBX5,TOP3B,GNAI2,DDX4,CAB39,KLK5,RBMX2,TNFRSF14,LDHAL6B,SNIP1,UBE2D1,RGS5,RAB1B,CRKL,SOS2,KDSR,DNAJC27,CDKN1A,RP2,FOXN2,SLITRK2,FBP1,CLIC2,NLRP1,PPFIA3,SF3B1,SUFU,APEX2,TMEM47,FBXL19,AP1S2,CHIC2,CDH11,TMEM185A,BAX,CRTC2,NUF2,COX6C,PICALM,DAPK3,COCH,RAPGEF5,IER2,HSD17B10,PPP1R1B,RND2,BMPR2,BCL9,RASD1,CBX3,NLRP3,OXSR1,DLST,ORC5,BAG3,BCL6,KRAS,RBM22,RRM1,DKK1,HERC4,USP6NL,SNX10,ZMYM3,SGMS1,RBBP8,CBLL1,UBA3,SRSF7,TRIM45,SAV1,STAT2,DUSP21,CDC7,ST6GAL1,FBXO8,IRAK4,WDR11,NHEJ1,TBC1D25,NBN,IL2,SNX22,CDC20,GNAO1,TIMP4,XRCC5,FBXL14,RHEB,PRKCE,TSPAN17,RAB27A,GRAP2,RNF133,COX6B2,CD81,ELK3,DPH3,DDX46,RHOBTB3,OCRL,UBE2E2,RPS6KA4,TNF,CCR4,KLF3,SERPINA1,SUMO2,DAAM1,NF2,PARP2,HSPA13,SESTD1,FOXA3,PPP2R5E,SH2D1A,MCL1,PLD3,NDUFA1,DKC1,ZBED1,FBXO44,PNMA3,RB1,TRIM29,TNKS2,NXT2,HSPB2,STK3,DCAF12L2,RHOBTB1,PTP4A3,FZD3,SPRED2,PCNA,DDX23,PIK3R2,JAK2,NDUFS6,TRIM36,NT5DC1,UBE2L3,PMAIP1,RAB39B,CSNK1G3,PGRMC1,FTSJ1,PTK7,DHX38,HUWE1,COX8A,USP8,CPLX2,TRIM34,ITGB5,PPFIA2,RGL2,FBXW11,NINJ1,BCL7C,TCEAL8,MAGEB10,CXCR3,SDHB,PCGF6,CCDC160,CXCL13,RORB,CKS2,YWHAZ,ICAM2,BOK,TNR,PTEN,RLIM,SURF2,MAGED2,CCNA2,UAP1,USP15,APOBEC3G,TSR2,NTRK2,SPP1,GNG12,RNF144B,DNAJB9,PLCB1,GNAZ,EPHA4,PSMD10,TNNI3K,CITED1,ARL4D,CDK12,FBXW7,FAF1,SRPK2,TAB2,TP53INP1,TRAF3IP3,DTWD1,RPA2,ASTN1,CCR1,PTPN11,NOTCH2,FBXL4,TNFSF8,FKBPL,RAB6A,USP16,RGN,TCEAL1,PLAC1,CDK7,SIN3A,CD40,TNFSF15,TLR8,ARFGEF1,RNF34,RAP2A,MSH6,PPP1R11,COPS7B,DENND2D,KLF4,ETF1,NCAPG2,POLE3,NFKBIA,RNF10,RPL10,FBXW4,HLF,SERPINC1,P2RY4,IP6K1,GPM6B,FBXO22,RFC3,STUB1,PIP4K2C,GPRASP2,PQBP1,ACVR1C,NKIRAS2,WDR45,SNRK,HSPB6,GNA11,SRSF2,HSPA5,SERPINB1,ITGB8,BTG2,VAV2,GNB3,HINFP,PLS3,TRIM44,TNKS,SLC22A17,STK4,PPP2R2C,PPP1R1A,MSTN,RNF148,PIGA,BTG3,GADD45A,GRPR,CCNH,EIF1AX,HSPD1,POLA2,POLB,PIAS1,PNPLA4,SAP18,DDR1,SPSB3,VAMP7,CTTN,RPL23,SPIN3,RABGGTB,FBXO7,NKAP,GNGT2,DMPK,CDC23,USP3,MPG,TGFBR2,TANK,TNFRSF1B,TIMP3,GMPS,PPP3R2,TTL,CCR7,RRAGB,PPP2CB,FKBP8,GABPA,RASL12,SMAD1,CYTH4,APOBEC3F,MAP2K1,PLCB2,FEZ1,OTX2,MAGEH1,EIF4A2,STAT5A,COPS5,TRIM26,ADAMTS10,UBE2G2,EP300,UPRT,FXN,RNF8,PEA15,LYZ,TOPORS,WSB1,LAMP2,NLRP9,SLC25A5,AR,ADCK1,SNRPB,TPM3,RIT1,PTPN4,FAM3C,PTP4A2,IMPA2,FEN1,FUNDC1,PRKACB,ASB7,TRAM1,TADA3,MGMT,SP1,MDC1,ROCK2,KRIT1,ELF5,TRAF6,SCML2,DNAJC19,TKTL1,ERAS,PLEKHO1,MYBL2,CNOT2,SPRY1,RUNX1,GJC1,SS18,TYMS,SCML1,UMPS,FCGR2B,DUSP3,SUCLG2,MTM1,BIRC2,SIAH2,CER1,MCM4,MAGEC2,PSEN1,EDA2R,FAM177A1,FKBP1B,LMO2,STARD4,THOC2,ORC6,DROSHA,DIRAS2,ARHGAP12,UBP1,IGF1R,CX3CR1,FOXP1,SLC4A10,TRIM6,ENC1,PLCXD3,MMP20,SMARCB1,RNF5,APEX1,AKT2,GAB1,FKBP1A,COTL1,RFC4,RPL39,TESK1,DVL2,BRD3,GLO1,PRKCA,RAB1A,PDCD1LG2,AMELX,EEF1A1,PIGK,GAS2,FBXO31,HNRNPH2,ANKRD10,CLIC4,ALDH1A3,ACVR1B,TIMM8A,EGR1,AIFM1,SNX14,AKAP17A,RAP1B,RAD21,DNAJB4,RACGAP1,CORO1C,GLRA2,HDAC3,RBM3,MAGEA4,PIK3CG,COX4I1,LRRC4B,UBE2S,RHOH,ARHGAP15,ANAPC4,DNAJC4,BCKDK,POLD4,AKT3,GRB10,CSNK1E,CHMP2B,PAK6,RBBP4,GPR34,XBP1,COX6A2,MAD2L2,ERCC3,ATF1,FAS,ARHGAP19,CUL3,NAP1L3,ARMCX3,SNRPA1,ABHD2,TP53I3,DDX1,KDM1A,CCDC22,RNF40,FKBP2,RALB,GMNN,UBE2H,ARL5B,CAMKV,ENO2,PSENEN,PNMA5,ELF1,SFRP1,LDB1,RANBP6,FGF23,BIRC5,RANBP1,ATF3,GNB1L,DNAJC2,ACSS2,RHOU,WDR82,DLG3,RPL22,CYTH2,RNF11,SNX11,S1PR4,UBE2V1,SERPINB9,HELT,PPP1R3C,CRADD,FZD6,MET,CDKN1B,COX7B2,NLGN1,HMGN4,PSMA6,AKAP1,PSEN2,SNX1,IL2RG,NCK1,STRADB,SIAH1,PLEKHF1,AHSA1,DUSP10,CDC42,SYK,ACO2,TRIM62,RASSF4,SERPINA3,CLK1,TRAF1,PPP1R8,BRS3,ZMAT3,RAB35,CD40LG,PTGER2,MYC,HERC3,PDCD10,VAPB,TOP2B,BAD,PRPS1,GPR173,GEMIN8,SERTAD1,ARF4,DNASE1L1,PML,PDCD5,DUSP6,HMGB1,GNG11,ARF1,KPNA6,TOX,COX7B,RHOG,FAM83A,ASB11,SDHC,RGS1,PPM1B,TRIM35,FBLN5,FOXD3,GPC4,CXCL10,SENP8,ASCC1,KIN,SMUG1,DUSP18,TP53,MID1IP1,G6PD,ADK,FTHL17,RALA,SERPINB6,SYBU,MAGEB1,DICER1,RNF128,PTGES,SAP30,TLR7,POU5F1,MSN,FGF16,PPP2R5A,MAP3K3,CCR5,SAR1B,RNF7,CAPG,EZH1,ZBTB16,MFAP1,MXD1,FBXO34,HCST,BRMS1L,UBE2I,MAP2K3,DOK5,STYK1,CXXC1,SPHK2,RCHY1,FGR,ARF6,LBR,FBXL7,TNIK,ORAI2,CHST7,SERPIND1,UBE3A,ENO1,SMARCE1,RGS6,CETN2,ZC4H2,CBFB,PRDX4,SLC25A14,MECP2,NUP35,TFPT,RIT2,ALOX5AP,BCAS4,TCEA1,CHN2,VCPIP1,USP30,RAD23B,JUNB,FOXJ3,SMAD9,PTPN5,CTNND1,KPNA2,STK38L,DDIT4,SMYD3,RAB3A,PIGC,SHC3,CDC26,DDIT3,FGF3,USP13,PLP2,NDP,NUP62,SMG5,RNF139,NEURL2,CMTM7,SNX12,IRF4,CCND3,RAB11B,ARL6,APPBP2,SH3BGRL,TNPO2,SRSF4,IL7,RAB9A,EEF1B2,PTPRZ1,ZNF189,SUPT4H1,VPS39,TFDP2,BCL2A1,ATP6V1D,CDKN2D,CDK17,FOXC2,RAB32,PITPNA,WNT10B,SPSB1,RBBP9,APOBEC3B,FBXO11,MLH3,PCBP4,TULP3,BMPR1B,RANBP10,MPP1,RBM41,PABPC5,FOXI3,HMGA1,PRKCB,SUV39H1,RGL1,TFRC,CKS1B,AUH,PLCL1,DIRAS3,YWHAH,ADAMTS20,DUSP22,HDAC11,DNAJC7,SKP1,PCYT1B,GJB1,LCP1 |
| 2.668e-11 | -24.35 | UBB (ubiquitin B) | protein interactions | 7314 | 427 | 183 | 19454 | 5460 |
HGS,OR4N2,CBLN4,PSMA2,USP30,PAEP,PRPS1,TRIM11,FAM168A,IKBKB,YWHAB,MAGOH,MGMT,TNNC2,PLPP4,YWHAG,SUMO2,SRSF1,NRSN1,MAGED2,UBAC2,FAM8A1,SYK,BORCS6,ADRB2,B9D2,YAF2,HSPA8,RAB30,HDAC5,PSMD14,FIS1,PSMA4,LMO2,MYC,CCNQ,CUTA,TAX1BP1,PSMD4,ZNRF1,MINDY3,TMEM31,TP53,MTCH2,COMMD8,ZMYM3,DUSP1,H2AX,RASL10B,RAB3B,CRYBA4,NEDD8,MEPCE,RUSF1,SMAD4,TUBG1,DNAJB2,ZFAND2B,VCPKMT,FZR1,UBE2N,SSR1,SDCBP,CSNK1G3,TRIM36,HEXIM1,NICN1,H2AB1,UBE2K,LITAF,KDM1A,NR1I3,UBE2E3,AKT1,TNFAIP3,PCBD1,ADRM1,MAP3K3,BUB3,RAPGEF5,TRAF1,CDC20,SMURF1,EZH2,RPN1,RNF126,AP2S1,FAF2,JUN,TRIM37,FANCG,UBE2A,AKT2,UBE3A,PCNA,TRAF6,BCL2L1,HAX1,CDKN1B,CDIP1,HMGA1,COPS7B,CACYBP,PHB1,USP46,ABCB1,PGRMC1,PLSCR4,CDKN1A,RNF11,TRIM5,CRY1,BRCA1,RHOB,YWHAZ,MED10,PFDN4,GRB10,SYCE3,HSD17B3,OTUD7B,CAV3,RNF40,RHEB,PRDX2,UBE2S,POLR2F,CTLA4,RNF181,RAD23B,TRAPPC13,SLC51A,FNTB,ATG4A,HUWE1,APBB3,LTBR,FAF1,NTRK2,IGF1R,EID1,ARL2BP,KXD1,HDAC6,SNAP91,EIF2B2,CITED1,MDM2,EEF1AKMT3,H2AZ1,DLGAP4,MYBL2,HAUS2,CNPPD1,UBA52,WDR83,PSMC4,CNP,FAXC,PRMT2,NUCKS1,DESI1,RHOU,SQSTM1,PRKCB,SCN1B,TEX19,PPTC7,CDC73,USP14,AR,FBXO7,BRAP,RHOJ,AANAT,UBB,CLRN2,UBE2L3,OPTN,STUB1,INPP5K,UBASH3B,ZBTB18 |
| 2.748e-11 | -24.32 | CREB3 (cAMP responsive element binding protein 3) | protein interactions | 10488 | 236 | 114 | 19454 | 5460 |
PLP1,CYBC1,SYNGR1,TECR,ATF4,GJB2,CREB3,MGST2,FMO1,ORMDL1,ITM2B,SLC2A3,HCFC2,TMEM243,SYVN1,FMO3,HDAC3,SEC22B,TRAM1L1,SLC7A9,TRAM1,USE1,LMNA,DRAM1,RPRM,CEBPG,FA2H,ADTRP,VTI1B,TMEM19,MOV10,RAB23,COPS5,DOLK,BTN2A2,AQP2,CLP1,TMED1,GLUL,STX8,LTA,RUSF1,CYBRD1,BCAP29,ERG28,UNC50,APH1A,DNAJC30,ERLEC1,TSPAN7,SFT2D2,SELENOK,SLC29A1,CREB3L4,SFTPC,NFE2L2,AGER,LMBR1L,SERINC1,RRAS2,RIMS3,ATP6AP2,NDUFB6,SLC41A3,RHEB,CYB561,CGRRF1,TMEM100,SLC38A1,PLN,FIS1,TMEM203,DDIT3,APPBP2,RABAC1,P4HA2,MRPL57,NFIL3,SYNPR,PSENEN,RNF41,STX7,CNPY3,TMEM115,FAM3C,FDFT1,FAM8A1,TMEM14A,FAM3A,SLC19A3,MFSD5,GJA1,OS9,PMP22,MARCHF5,PTDSS1,EMC6,SCAMP5,FXYD6,BCL2L1,AQP4,SLC39A13,ATF3,TRIM26,SACM1L,SAR1B,NEU1,TOP3B,JUN,ASPM,SEC61G,CYB5B,TMEM14B,CCR1 |
| 2.799e-11 | -24.30 | RASTRNSFRMNG | prints domains | PR00449 | 135 | 76 | 5227 | 1528 |
RAB1B,RASL11A,ARHGAP5,RAB23,DIRAS1,CDC42,RABL2B,NKIRAS1,MRAS,RAB29,RHEB,RAB28,RAB9A,DIRAS3,ARL4A,RASD1,RAC2,RAB39B,RAB33B,RAB18,DIRAS2,RAB3D,RAB37,RIT2,RAB33A,RHOU,KRAS,RAP1A,RABL3,RAB6A,RASL10B,ERAS,RHOBTB1,RAB9B,RND3,RAB3B,HRAS,RHOH,RAB14,RAB27A,RASL12,RAB5C,RASL10A,RAB11B,RRAS2,NKIRAS2,RIT1,RAB19,RAB8B,RHOG,RAB3A,RHOB,RAB4A,RAB13,DNAJC27,RAB1A,RAP2C,RHOJ,RAB35,RALB,RAB22A,RAB40AL,RAB6B,RAB2A,RND2,RALA,RERG,RAB30,RAB3C,RAB32,RAB31,RAP2A,RAB5A,RAB11A,RAP2B,RAP1B |
| 3.085e-11 | -24.20 | POLR2A (RNA polymerase II subunit A) | protein interactions | 5430 | 491 | 205 | 19454 | 5460 |
VIRMA,UBE2L3,POLR3H,PTEN,RPS20,FBLN5,CCNF,PPIG,CDC73,IVNS1ABP,NONO,PPP1CC,FBXW7,HMGB1,GTF2I,TCEA1,SIRT7,RPA3,SOD1,LMNA,CTDSP1,CDK7,ELP3,MED30,CCND1,ATG16L1,BRINP1,NCBP2,CDK9,TOP1,POLR2I,DCUN1D1,SSU72,MED21,GTF2A2,GTF2E1,ERCC3,NFKB1,MOV10,RIGI,PTGES3,SMN1,MDC1,SOCS2,CSH1,DNAAF10,SEM1,CPNE2,PQBP1,POLR2G,CTDSP2,EEF1A1,PSMB9,TAF11,ACTB,MED17,POLR2F,POLR3B,SNRPD1,SNRPD2,CPSF1,HTRA2,PFDN2,MYO6,BRCA1,MED10,TAFAZZIN,MCM3,CUL2,CUL3,MED11,IFTAP,MED23,SUPT4H1,CDKN1A,ACTL6A,EGLN3,COPS2,FBXO32,NABP1,PHB1,MED4,HNRNPD,PRPF19,HMGA1,IMMP2L,SSRP1,COPS4,GTF3C3,ASF1A,PCNA,TRIP4,POLR2D,POLR2C,EZH2,LGR4,GTF2E2,VDR,SRC,SRPK2,SMURF1,CSTF3,IFI6,EGLN2,CSNK2B,LIG3,PSMA6,UBN1,CREB1,UBE2H,ATP1A1,STN1,MED22,SUB1,POLR1H,ELOF1,IRF3,ZNF326,HBB,WWP1,RPRD1B,RPA2,SMYD3,XBP1,CCNH,AGO1,CXCL8,POLR1D,GTF2H4,CDC5L,KLK3,CAND1,ALYREF,GTF2B,MAP4,AKAP8L,CDK12,SNRNP70,MED29,MED27,COPS5,CSNK2A1,MNAT1,PDRG1,PSMA5,DHX9,SNIP1,CBX3,CDK8,H2AX,RPAP2,TP53,KBTBD4,POLR2B,FBXO22,GTF2F2,GTF2F1,PRMT5,INTS10,NFKBIA,POLR1B,CRMP1,SNRPB,CPSF2,DRAP1,MYC,CREBBP,COPS7A,LMO2,SRSF2,DDX5,MED13L,EP300,HSPA8,XRCC5,HIRA,SNRPA,PIH1D1,MED31,SNRPD3,SUMO2,EED,WDR82,POLR2L,TRAM2,RPRD1A,AGR2,CTNNB1,XPO1,WWP2,IFI16,BAZ1B,KRAS,HNRNPF,FAM168A,EWSR1,RPAP3,RUVBL2,TAF10,SMARCB1,MTA2,HDAC11,SUPT5H,MED9,TOP3B |
| 3.234e-11 | -24.15 | mRNA Splicing - Major Pathway | REACTOME pathways | R-HSA-72163 | 187 | 102 | 10285 | 3229 |
HNRNPC,DHX15,DNAJC8,HNRNPF,CASC3,PPIH,CD2BP2,HNRNPD,LSM3,SRSF4,CWC15,MAGOH,PRPF31,DHX16,SNRPN,HNRNPA0,POLR2B,TRA2B,SF3B1,GTF2F2,SNRPB,PQBP1,POLR2G,PRCC,PPWD1,SUGP1,SF3A1,ELAVL2,DHX38,SNRPB2,CLP1,CPSF2,POLR2C,SF3B4,TFIP11,SMNDC1,SNRNP70,HNRNPH2,MAGOHB,DDX5,NCBP2,PAPOLA,SNRPD3,USP39,SNRPE,TXNL4A,SNRPD2,LSM6,LSM5,LSM2,LSM4,CDC40,GCFC2,HNRNPL,SRSF1,BUD31,MIR636,SF3B5,MIR7-1,SNRPA1,SNRPD1,HNRNPA2B1,CPSF4,PRPF19,CSTF2T,MIR1234,UPF3B,DDX23,MIR939,POLR2F,DDX42,POLR2D,POLR2L,WBP11,HSPA8,SNRPG,PRPF4,EIF4A3,HNRNPK,ALYREF,DDX46,SRSF7,LSM8,SRSF2,SRSF10,SNRNP27,CDC5L,POLR2I,SNRPA,GTF2F1,DHX9,RBM22,RBM5,HNRNPA1,CSTF3,SLU7,SF3B6,CTNNBL1,CPSF1,RBM17,SNRNP40,CCAR1 |
| 3.237e-11 | -24.15 | ubiquitin-dependent protein catabolic process | biological process | GO:0006511 | 484 | 210 | 18204 | 5365 |
TRIP4,PSMB4,CHMP1B,ANKIB1,CRBN,HUWE1,DDIT3,SQSTM1,FBXL7,SPOPL,DTL,MDM2,RNF146,FBXL3,CDC26,PSMB5,CDC23,FBXL14,TRIM45,CACUL1,UBE2D3,ZFAND2B,ANAPC16,VPS4A,ADRM1,CUL3,KLF1,COP1,UFD1,KLHL22,HECTD1,ZNRF1,RNF20,CHMP5,RNF148,PSMD1,TRIM3,RNF187,CHMP4C,AREL1,FBXO44,CSNK1A1,UBE2H,NFE2L2,FBXO7,RNF139,CUL2,SIAH1,RBCK1,FBXO22,FAF1,PSMB9,CCAR1,SPSB3,RNF115,BFAR,STUB1,FEM1A,PSMD4,PSMC1,ANAPC13,NSFL1C,VPS28,UBL4A,SH3BGRL,HECW1,HDAC6,RNF5,FBXW7,PSMD3,PSMA1,UBAP1,APPBP2,KCTD10,GID4,FBXO31,UBE2L3,TRIM32,PSMC4,BIRC2,ELOC,KBTBD6,PSMA2,RNF144B,NAE1,RAD23B,MYLIP,CCNF,RNF10,RNF40,FBXO3,RNF133,PSMD14,RNF26,PSMC5,DISC1,FBXW4,RMND5B,PML,FBXW11,UBXN2B,TNFAIP1,HECTD3,RNF122,PPP2CB,PSMA6,HERC3,FBXO8,UBE2A,KLHL25,RNF34,PELI1,RNF14,UBE3A,WWP2,UBE2K,CDC16,TOM1L1,ANAPC4,USP38,FBXO11,RCHY1,CHMP1A,PSMB7,CDC20,FAF2,FZR1,SMURF1,PSMB10,SPOP,KLHL3,RHOBTB3,UBE2B,PSMB11,WWP1,MAEA,ANAPC2,UBE2I,MTM1,TRIM26,UBE2S,PSMB2,ECRG4,IFI27,PSMB6,CHMP2A,RC3H2,CHMP2B,RNF7,BAP1,ANAPC15,KCTD17,TP53INP2,UBE2G2,HERC4,SIAH2,FEM1B,AKT1,RNF8,RNF128,VPS4B,RNF167,UCHL3,FEM1C,PPP1R11,UBE2W,DCAF11,PSMD6,PSMA4,ARMC8,KLHL15,RLIM,WDR77,ZFAND2A,FBXO9,NEDD8,PSMD12,PSMA5,RNF11,GID8,CTNNB1,TNFAIP3,OTUD7B,FBXL4,TOLLIP,XBP1,CBL,NDFIP1,SPSB1,PSMB3,PLAA,SKP1,PSMC3,PSMB1,TOPORS,UBE2D1,UBE2N,TSG101,USP14,EDEM1,FBXL19,OS9,ANAPC11,GSK3A,HGS,PSMA3,SYVN1,PSMD7,RNF126,DERL1 |
| 3.364e-11 | -24.12 | ESYT1 (extended synaptotagmin 1) | protein interactions | 23344 | 408 | 176 | 19454 | 5460 |
GPM6B,CYP2C9,TSPAN11,TOMM6,KRAS,ARHGAP15,DNAJC25,TOP3B,STBD1,RND3,MOB3C,RAB4A,PTRH2,STX5,RAB35,RHOH,OSBP,YWHAG,YWHAH,DDRGK1,FAM241A,LAMP2,SYNJ2BP,RAB5C,RPL6,YWHAB,DEGS1,AGR2,HSPA8,RAB5A,EMC1,STAU1,SEC62,YIPF5,LMBR1L,ATP6AP2,TAX1BP1,MYC,FIS1,PDF,STX18,PAQR9,RDH11,FKBP8,SRPRB,RAB3B,ATP5PB,PREB,SNAP29,TP53,MTCH2,RAC2,STT3A,COQ8A,CAMLG,COMT,TMPO,STX6,LMAN1,RPS16,DNAJC1,ARL6IP5,DPP4,DHRS7,FAM20C,EDEM1,CHCHD1,DERL1,RAB9A,CYP2C18,TEX264,CDC42,CFTR,LEMD3,RPA2,FGFR1,SSR1,SEC61A1,ATL1,UGT1A1,UBE2H,SCD5,BAG2,TMT1A,RETREG1,G3BP1,FAF2,DCAKD,MACO1,RAF1,EMC10,PLD3,RPN1,STIM1,EZH2,GJA1,ERLIN1,NUP35,STOML2,RB1CC1,RHOG,PMAIP1,ATP5MK,TSPAN15,STX7,PXMP2,RND2,OTULINL,CDKN1A,TOR1AIP2,PGRMC1,VAPB,ARMCX3,RMDN3,GPR89A,SEC61B,FAU,CHCHD3,CHP1,REEP4,VEZT,RAB11A,CUL3,SCFD1,NTRK3,VMP1,FAS,YWHAZ,RHOB,EMC2,IGF1R,NSDHL,SLC25A10,SFXN1,PSEN1,LBR,CCDC47,TMEM126A,HSD17B11,CDCA3,SRPRA,PTPN1,MDM2,CAV1,ARF6,DERL2,HM13,LAMP3,TMEM199,SLC25A46,EMC4,STYK1,OSBPL8,POR,SYVN1,RTN4,NCDN,RHOU,RPA3,TMEM209,YKT6,ST7,RABL3,ARHGAP1,SEC22B,EPHX1,GRM2,HSP90B1,CCNF,VAMP3,SEC63,VIRMA,COPE,RHOJ,HMOX2,AP2A1 |
| 3.369e-11 | -24.11 | response to external biotic stimulus | biological process | GO:0043207 | 1366 | 511 | 18204 | 5365 |
RAB29,DEFB116,DEFB1,GJB2,FGF10,TRIM8,IL18BP,NCK1,JAGN1,TF,LIAS,ACTA2,CD209,PLSCR3,SRPK2,NOTCH2,FCN2,CLPB,IL1A,MAP2K3,CCR7,DDIT4,ISG15,UAP1,HCFC2,CXCL1,JCHAIN,CCL20,CST11,WFDC13,MTDH,WASL,NFKBIB,PTPN22,IRF2,C1QC,TTC4,DHX9,VAMP8,FMO1,CHGA,IRF8,SHC1,HDAC5,MRC1,MAP3K14,LTA,FOSL2,OAS1,CCDC92,FCGR1A,REG1A,USP14,H2BC11,NLRP6,TLR7,IRF7,TMEM255A,TRIM29,DHX15,ATP1B1,IFI35,BECN1,LITAF,CYP1A1,BANF1,HNRNPA0,EXOSC4,MIR20A,CCL21,CYBC1,TRIM22,STAT2,CCR5,FAM3A,IER3,PTGER2,CCL17,MIR142,APOBEC3G,HSPB1,PRDX3,IFNAR1,CDC42,DAPK1,G3BP1,CNPY3,CCL5,AKAP12,DEFB124,TLR3,TRIM68,STX8,HSP90AA1,IRF3,CSF2,CFL1,AKAP1,TNFSF8,BPIFB3,CCL3,APOBEC3D,MIF,SAP30BP,ELMOD2,LILRB1,MOV10,PELI3,IL12A,REN,BCL10,RAB1A,TAX1BP1,ODC1,PIM2,ZYX,POLR3H,MEF2C,MSRB1,TRIM11,IFNB1,CAV1,CHID1,NCR3LG1,MAVS,CLDN1,CCDC186,RNASE1,CD46,APOBEC3F,MIR146A,TRIM26,PLPP6,NLRP9,CD4,GFI1,IRF9,SLPI,IFIH1,MYD88,MIR421,MIR342,SNX3,TRAF2,CX3CR1,NMBR,TRIM6,LY96,PHB1,VAMP7,PSMA2,PDE12,PLAAT3,ADIPOQ,TNF,DEFB121,RBPJ,PTGFR,IL10,XCL1,RAF1,CX3CL1,RNF5,ITGB8,CXCR4,IL1RAP,DUSP10,BATF,HRAS,PYCARD,MBL2,HMGB1,CD1D,EPHA2,PLAC8,CXCL12,PTGER1,CCL18,CASP4,NLRP2,TRIM23,CITED1,CGAS,LSM14A,CXCL10,VAMP2,TNFRSF14,APOBEC3B,MIR105-1,LRAT,TIFA,IRF4,F2,AIF1,CLDN3,FBXO3,MAPKAPK3,PDCD1LG2,PLSCR1,MIR17,PPM1D,CEBPG,NLRP3,CCL25,IL21,AZI2,CLEC7A,CNP,H2BC12,IL13,ENDOD1,SOD2,RGS1,LYZL4,CXCL8,SPAG11B,TP53,ARF1,IDO1,CCL8,TOMM70,CCL11,TRIM27,SEC11A,TLR4,IFI6,SEC14L1,NONO,CDK6,MIR26B,UGT1A1,PRDX2,TMEM33,BPIFA2,B2M,YTHDF2,DROSHA,EPO,LGALS3,CNOT7,SDHAF4,TRIM15,IL34,IKBKB,RBCK1,GPM6A,GAPDH,CYP27B1,SLC17A5,SLC15A2,PPARG,CXCL13,APOBEC3H,PTGER4,LYG2,TRIM52,TSPO,NQO1,CHMP5,IRAK4,TNFAIP8L2,GSTP1,HYAL2,MIR95,BAK1,TNFAIP3,GPX1,TMEM106A,CCL24,CXCL11,PPP1R11,UBE2W,ROMO1,NFKBIA,CALR,GRPR,FBXO9,MIR675,TLR6,IFNA13,SELENOS,TANK,ISG20,DEFB129,CEBPE,ZMYND11,IL1B,AKT1,MIR545,PRKCE,LACC1,RAB27A,DIO2,KRT8,DEFB114,LYZL6,JAK2,STXBP1,BCL2L1,TIRAP,MIR187,ACP5,STAT1,BST2,MIRLET7B,PLAA,MIR130A,CNR1,TMEM229B,KLRD1,UBE2N,TOLLIP,XBP1,CDC42EP2,CREBZF,RPL13A,TUBB4B,CD14,EIF2AK2,RSAD2,GTF2F1,IL6,RTP4,PI3,BAX,LSM5,IFNA10,CD86,PYDC2,MMP9,G3BP2,MIR223,FOXP1,CXCL9,DDX1,FCER1G,MX2,IL12B,TREML1,FGR,RNASEL,POLR3B,RNASE6,DAPK3,CXCL14,RPL39,IFNGR1,ST13,PELI1,TRIM34,VPS26B,MATR3,TMED1,CD274,FOXP3,MX1,ENO1,CD36,TPT1,HP,CD80,CDC42EP4,RBBP9,PMAIP1,POLR3F,OPTN,LDOC1,IFI27,RIGI,SIN3A,LYAR,NMI,CLEC6A,LILRA2,DHX16,AQP4,EEF1G,DNAJC3,CXCL3,FABP4,CDC73,IFNA2,MIR21,TNFRSF1B,IFNK,ATG7,PCK2,TLR9,OCIAD2,SH2D1A,JAK1,WFDC5,SYNCRIP,EXOC1,MGST2,LEAP2,PLSCR4,TUSC2,GPAM,KLRC2,DEFB115,TRIM32,LACRT,YES1,NPC2,TRIM62,ATG16L1,SARM1,LGALS8,IFIT2,CD2,SMAD3,RNASE9,FCGR2B,S100A8,NFKBIL1,TRIM5,STAP1,APOBEC3C,CCR4,NLRP1,CLU,SYK,CH25H,CD40,RAB14,CCL23,OTULIN,WDR83,KCNJ8,NFKB1,ARG2,RNASET2,CCL4L1,PSPC1,CCL2,SEMG2,FOS,TASL,TUBB,PML,TLR5,CCL19,VAMP3,SFTPD,CDK4,XRCC5,TBK1,CYRIB,BPGM,TRIB1,THBD,APOBEC3A,CD2AP,TLR10,TICAM2,TRAF6,TLR2,RARRES2,PRKRA,PDCD4,LGR4,CAMP,TMEM45B,CD47,IL17F,IFNG,TAB2,FAU,SERINC3,CD58,ZNF175,COTL1,PHB2,HEXIM1,FASLG,RNASE4,REG1B,PIK3CG,PDE4B,TRIM21,TFEB,MIR140,IL18,PRDX1,EXT1,TRIM35,SRC,NT5C3A,IL23A,BNIP3L,LYZ,SAMHD1,TICAM1,TLR1,MECP2,ALPL,IVNS1ABP,MIRLET7I,CCT5,CAPN2,TLR8,NDUFAF4,OPRK1,IFI16,ACTR2,BPIFB1,TRIM10,CCL1,IRF1,PQBP1 |
| 3.379e-11 | -24.11 | METAP2 (methionyl aminopeptidase 2) | protein interactions | 10988 | 277 | 129 | 19454 | 5460 |
GAPDH,RPS2,RPL10A,RPL24,RPL12,SYNCRIP,RPL32,RPL35A,RPS16,RPS27L,RPL15,RPSA,CENPM,CCT5,SESN2,SRP72,GINS4,RPL3,ABCE1,RPL23A,DHX9,NKRF,RPS13,RPL17,EIF3E,SNRPG,SRPRB,RPS17,RSPH1,RPL7A,MECP2,EIF3G,SRP54,EIF2S2,RPS20,TMEM108,ZMAT5,RPS12,PELP1,RPS3,EIF2AK2,CTTN,METAP2,CSTF3,RPL22,COPE,RPL13A,CDC42,ATG16L1,RPS14,RPLP0,RPL26L1,SSR1,CWF19L1,MTDH,SQSTM1,RPL27,EIF4E,RGS2,RPS15,RPL4,DLK2,XPO1,EIF3D,HMGA1,RPL6,DRG1,RPLP1,RPLP2,RPL8,RPL9,TMEM237,OPRL1,CCT7,NOB1,EIF2S1,RPS10,RPL7,LYAR,OTUD6B,RPL29,RPS7,MAX,RAF1,MED9,E2F4,GPBP1L1,RPS11,RPS23,RPL18,RPN1,RPS24,RPL31,PABPC1,PPWD1,RPS4X,RPL28,KRAS,TMEM213,RPL39,MYC,NDUFB7,RPS26,RPS5,RIT1,CCT2,H1-10,RPL37A,RPS9,FAU,EIF3K,VPS72,RPL10,PRRC2A,RPL19,GNB1,RPL35,ACTL6A,RPL27A,EIF4B,NUFIP2,PIH1D1,DNAJC27,ATP5PO,RNF7,HSPA8,RPS28,STAU1,ATAD1 |
| 3.381e-11 | -24.11 | response to other organism | biological process | GO:0051707 | 1363 | 510 | 18204 | 5365 |
YES1,LACRT,NPC2,TRIM62,PLSCR4,TRIM32,KLRC2,DEFB115,GPAM,TUSC2,RNASE9,SMAD3,SARM1,ATG16L1,CD2,IFIT2,LGALS8,TRIM5,STAP1,APOBEC3C,S100A8,FCGR2B,NFKBIL1,OTULIN,CCL23,RAB14,CD40,WDR83,NLRP1,CCR4,CH25H,SYK,CLU,CCL4L1,NFKB1,KCNJ8,RNASET2,ARG2,TUBB,PML,FOS,SEMG2,PSPC1,CCL2,TASL,CDK4,CYRIB,TRIB1,TBK1,BPGM,XRCC5,SFTPD,VAMP3,CCL19,TLR5,TICAM2,TLR10,RARRES2,TLR2,TRAF6,CD2AP,APOBEC3A,THBD,LGR4,CAMP,TMEM45B,PRKRA,PDCD4,TAB2,IFNG,SERINC3,FAU,IL17F,CD47,RNASE4,FASLG,MIR140,TFEB,TRIM21,PDE4B,PIK3CG,REG1B,CD58,HEXIM1,ZNF175,PHB2,COTL1,TRIM35,NT5C3A,SRC,IL18,EXT1,PRDX1,SAMHD1,LYZ,BNIP3L,IL23A,MIRLET7I,IVNS1ABP,ALPL,MECP2,TICAM1,TLR1,ACTR2,BPIFB1,CAPN2,CCT5,OPRK1,IFI16,NDUFAF4,TLR8,CCL1,PQBP1,IRF1,TRIM10,GPX1,CCL24,CXCL11,TMEM106A,BAK1,MIR95,GSTP1,HYAL2,TNFAIP3,CALR,MIR675,FBXO9,UBE2W,PPP1R11,NFKBIA,ROMO1,ISG20,TANK,SELENOS,TLR6,IFNA13,IL1B,AKT1,ZMYND11,CEBPE,DEFB129,DIO2,RAB27A,KRT8,DEFB114,PRKCE,MIR545,LACC1,MIR187,TIRAP,BST2,STAT1,ACP5,STXBP1,JAK2,LYZL6,BCL2L1,TMEM229B,CNR1,UBE2N,KLRD1,MIR130A,PLAA,MIRLET7B,TUBB4B,CD14,EIF2AK2,TOLLIP,RPL13A,CREBZF,CDC42EP2,XBP1,MMP9,PYDC2,CD86,IFNA10,LSM5,IL6,GTF2F1,RSAD2,PI3,BAX,RTP4,TREML1,IL12B,MX2,FCER1G,DDX1,RNASE6,POLR3B,RNASEL,FGR,MIR223,G3BP2,CXCL9,FOXP1,RPL39,CXCL14,DAPK3,PELI1,ST13,IFNGR1,TMED1,MATR3,ENO1,MX1,FOXP3,CD274,TRIM34,VPS26B,LDOC1,CDC42EP4,RBBP9,CD80,HP,CD36,TPT1,OPTN,POLR3F,PMAIP1,NMI,CLEC6A,RIGI,SIN3A,IFI27,LYAR,CXCL3,FABP4,DNAJC3,EEF1G,MIR21,IFNA2,CDC73,AQP4,DHX16,LILRA2,JAK1,OCIAD2,SH2D1A,LEAP2,MGST2,SYNCRIP,EXOC1,WFDC5,TLR9,PCK2,ATG7,IFNK,TNFRSF1B,PHB1,LY96,TRIM6,PDE12,PSMA2,VAMP7,CX3CR1,TRAF2,NMBR,XCL1,IL10,RBPJ,PTGFR,CX3CL1,RAF1,TNF,ADIPOQ,PLAAT3,DEFB121,BATF,DUSP10,IL1RAP,HRAS,PYCARD,CXCR4,ITGB8,RNF5,CXCL12,PLAC8,EPHA2,MBL2,CD1D,HMGB1,TRIM23,CITED1,NLRP2,CGAS,CASP4,CCL18,PTGER1,APOBEC3B,LRAT,MIR105-1,LSM14A,TNFRSF14,VAMP2,CXCL10,MAPKAPK3,FBXO3,PLSCR1,PDCD1LG2,AIF1,F2,IRF4,TIFA,CLDN3,CEBPG,NLRP3,CCL25,MIR17,PPM1D,IL13,H2BC12,CNP,SOD2,ENDOD1,CLEC7A,IL21,AZI2,TP53,SPAG11B,IDO1,ARF1,CXCL8,LYZL4,RGS1,IFI6,SEC11A,TLR4,TRIM27,NONO,CDK6,SEC14L1,CCL8,CCL11,TOMM70,BPIFA2,PRDX2,UGT1A1,MIR26B,TMEM33,DROSHA,B2M,YTHDF2,TRIM15,CNOT7,SDHAF4,GAPDH,SLC17A5,CYP27B1,GPM6A,RBCK1,IKBKB,IL34,EPO,LGALS3,APOBEC3H,LYG2,PTGER4,PPARG,SLC15A2,CXCL13,IRAK4,CHMP5,TNFAIP8L2,TRIM52,NQO1,TSPO,JAGN1,NCK1,TRIM8,IL18BP,LIAS,TF,DEFB116,RAB29,FGF10,GJB2,DEFB1,IL1A,MAP2K3,CLPB,FCN2,CD209,ACTA2,NOTCH2,SRPK2,PLSCR3,HCFC2,MTDH,CST11,WFDC13,JCHAIN,CCL20,CXCL1,ISG15,DDIT4,CCR7,UAP1,TTC4,C1QC,FMO1,VAMP8,DHX9,PTPN22,WASL,NFKBIB,IRF2,CCDC92,OAS1,REG1A,FCGR1A,MRC1,HDAC5,SHC1,IRF8,CHGA,FOSL2,LTA,MAP3K14,DHX15,TRIM29,TMEM255A,IRF7,TLR7,NLRP6,H2BC11,USP14,BANF1,CYP1A1,LITAF,ATP1B1,BECN1,IFI35,STAT2,FAM3A,CCR5,CYBC1,CCL21,MIR20A,EXOSC4,HNRNPA0,TRIM22,PRDX3,HSPB1,APOBEC3G,MIR142,DAPK1,CDC42,IFNAR1,IER3,CCL17,PTGER2,TLR3,TRIM68,DEFB124,AKAP12,CNPY3,CCL5,G3BP1,CFL1,TNFSF8,AKAP1,IRF3,STX8,HSP90AA1,CSF2,PELI3,MOV10,LILRB1,ELMOD2,SAP30BP,BCL10,REN,IL12A,MIF,APOBEC3D,CCL3,BPIFB3,POLR3H,MEF2C,MSRB1,TAX1BP1,RAB1A,ZYX,ODC1,PIM2,MAVS,CAV1,IFNB1,TRIM11,NCR3LG1,CHID1,MIR146A,CD4,NLRP9,PLPP6,TRIM26,CCDC186,CLDN1,APOBEC3F,RNASE1,CD46,SNX3,MIR342,MIR421,MYD88,SLPI,GFI1,IRF9,IFIH1 |
| 3.385e-11 | -24.11 | DOT1L (DOT1 like histone lysine methyltransferase) | protein interactions | 84444 | 798 | 308 | 19454 | 5460 |
SNRPD2,SNRPD1,SEC61B,RPS9,CPSF1,FAU,GNG12,RSRC1,PRRC2A,RPL19,ERH,GNB1,RBBP4,RPL35,RPL7L1,SMARCE1,RFC5,PRPF31,RPS29,RBM15B,NOP16,HSP90AA1,RPS5,C1D,CCDC86,COIL,G3BP2,UNC45A,SKP1,NOP53,YTHDF1,PPP1CB,PRDX3,ACTL6A,TOR1AIP2,MYL6,USP39,H2AC1,HP1BP3,RPL8,THOC2,RPL9,MRTO4,SRSF10,DHX15,CETN2,NOP58,RPL7,AGK,ATXN10,HNRNPA1,TRA2A,DPY30,HNRNPD,HAX1,MRPS26,RPL23,BCL2L1,MPHOSPH6,WDR12,DROSHA,SLC39A7,BAG2,SRSF7,SLC25A5,HNRNPA2B1,PPAN,SRSF4,GTF3C3,SSRP1,FLOT1,RFC3,RFC2,RBBP7,ZNF592,G3BP1,ASF1A,RPL29,ACTN4,NUP153,ERLIN2,FEN1,RPS11,SNRPE,VPS33A,RPN1,EXOSC3,RTRAF,RPS20,RPS12,PELP1,TECR,GNAI2,VIRMA,DEK,TMOD3,RPL13A,RPL26,HMOX2,RACGAP1,PPP1CC,AR,NONO,ZNF687,PPIH,SQSTM1,PRPF4,NHP2,AATF,GTF2I,NPM3,B2M,SMC4,HACD2,BRINP1,SF3A1,SNRPN,RPL26L1,WTAP,CDK1,MRPS34,HSP90B1,PWP2,RPL12,HACD3,KRR1,UBP1,CDK9,NOP9,MRPS23,RPL35A,MOV10,SPATS2L,LRRC8B,BRD3,FOXP1,MPHOSPH10,RPL23A,ZC3H11A,SLC25A10,PPP1R12A,NKRF,TCOF1,CTNND1,RPS13,SMN1,MDC1,EIF3E,SNRPG,PAK1IP1,THRAP3,DDX39A,CD2BP2,MLLT6,RPL15,EXOSC8,RAD23B,LLPH,DMAP1,SF3B4,SMU1,DLST,APEX1,MATR3,ATP5F1B,STAT1,CAVIN2,SNRNP40,HNRNPAB,LDHB,PSMA4,RPS26,THOC6,RCL1,POLR1B,H1-1,NSA2,CIRBP,FTSJ3,RBM27,H1-10,CHTOP,HSPA8,DDX5,RFC4,RPS28,XRCC5,SPECC1L,SAP18,GNB4,PACSIN3,SRSF2,FXR2,TRA2B,HNRNPA0,MRPL12,ZC3H14,NCOA5,CORO1C,RBM5,FUBP3,SRSF1,PEG10,EIF2S1,FAM98A,RPS10,HNRNPL,LYAR,SNRPA1,XPO1,CTNNB1,TBC1D10C,NGDN,BAZ1B,IFI16,DDX50,RPL6,PTDSS1,DDX1,MAGOH,YWHAB,RUVBL2,MYO1B,RTCB,NDUFB5,PABPC1,LSM14A,TOP2B,RPS4X,CCAR1,CDCA7L,POLDIP3,RUVBL1,RPS7,TOP3B,TRMT1L,SUPT5H,ZRANB2,SMARCB1,MTA2,RPS23,RPL18,SEC61G,SEC61A1,SF3B6,PSPC1,SRPK2,BCCIP,RSL24D1,RPS17,CFL1,TIA1,RPF2,SMARCA5,EXOSC1,RBM7,CALU,RRP7A,GEMIN8,EXOSC4,TWNK,RPL27,DDX46,HCFC2,MARS1,WDR3,TRAM1,GTF3C4,HEXIM1,TFIP11,LUC7L3,ZNF326,MCL1,MRPS9,SSBP1,STT3A,SYNCRIP,EEF1B2,RPL32,ALYREF,MYL12A,CDC5L,SURF6,RPS16,RPS27L,PGAM1,NOL12,AKAP8L,RPS2,RPL10A,RPL24,RPL3,DHX9,SLC25A11,MEPCE,CAPZA1,PSMA5,KPNA2,IMP4,ZMYM3,ZMYM4,IMP3,TP53,DDX42,TFCP2,IK,ARPC3,RBM34 |
| 3.405e-11 | -24.10 | synapse | cellular component | GO:0045202 | 1473 | 540 | 19108 | 5553 |
GLRA2,PTEN,LPAR1,CYFIP2,SLC6A1,BORCS5,NDE1,CORO1C,FGF12,GABRB3,CAMK2N2,PDYN,EFNA5,PDE2A,OLFM3,YWHAZ,C1QL2,RPS27A,SLC6A12,ABHD17A,RPS9,SLC1A2,MTMR2,GRAP,CPLX3,BMPR2,RHEB,PMP22,ADRB1,CHN2,PAK6,DLG3,NOG,CHRNB2,INPP4A,GSK3A,STX6,SLC18B1,RS1,LIN7C,CNTNAP1,LHFPL4,LYPD6,CAV3,TMED9,RPL24,CDH8,BCL2L1,TIAM1,CHRDL1,ELFN1,RPS14,GUCY1B1,CDC42,GNAQ,MAP1S,TBC1D24,CDH11,RPS23,HNRNPD,RAB8B,DRD3,SNAP29,SNCG,KCNA2,ZDHHC17,RPS11,LIN7B,GIT2,SYT2,GLRA1,TPBG,DROSHA,AGER,RAP2A,GABRB2,ATP1A3,ATAD1,RAB3C,DLG1,WASF3,NGDN,SLC39A3,CHRNA7,GPM6A,CBLN4,ARF4,NRN1,EIF3E,ADD2,CTTNBP2,AP3S2,PSENEN,SIGMAR1,GJC1,TRAPPC4,SNAP25,HTR2A,SV2B,MPZ,VDAC1,EIF4A3,PLCXD3,DLG4,SPOCK1,SLC6A7,VAC14,DAG1,KCNB1,RPL7,RIC3,STAC3,SLC17A5,PSD2,DGCR8,TNIK,SST,ACHE,CNP,ATP6V1A,CNTN2,CRHBP,PPT1,AKT1,PLG,PPFIA3,CBLN3,LRRC4B,STX16,LARGE1,PCDH17,RPL12,VAMP3,GABBR1,P2RY1,ACTL9,PRKCE,SLC2A1,LRFN3,PDE4B,ATP6V1D,HNRNPF,LYNX1,NPY5R,STX11,RAB4A,MME,KCNJ8,NAPA,HNRNPA0,MAP1LC3A,RNF10,SLC4A10,GRM2,NDFIP1,C9orf72,AP2A1,NLGN2,ROCK1,EIF2S1,PAK2,GRID1,RIT2,SLC6A11,CBLN2,SLC4A8,AP2S1,IL1RAP,RTN4,LAMB2,CASK,RANBP6,EIF4E,RHOB,FCGR2B,TPPP,FRRS1L,NRP1,SLC32A1,RPS15,SLITRK2,SLC6A6,SYT4,CDK5R1,KCNC1,HTR1F,TMOD2,NETO2,INSYN1,WNT7A,ASIC2,CTBP1,CUL3,PLAA,MKLN1,CBLN1,PPP2R1A,CAMKV,RABAC1,RPLP0,PSMC4,INA,HAPLN2,ATP6AP2,CTNNB1,RPS6KA4,RAB5C,PGRMC1,PTPRZ1,KCNJ10,RIMS4,SYN3,SNAP23,CAP2,ATP2B4,STX1A,ASIC1,GRM1,PRKCB,CRKL,SNAPIN,SNTA1,NTRK2,PPFIBP1,TRIP4,IQSEC1,UTS2,HSPA8,STX12,GPC4,PPFIA2,AP2M1,SYNGR4,NPTX1,LGI3,DES,EIF2S2,GPR37,PHACTR1,CHRM1,RALA,ADORA3,APH1A,GNB1,ARF1,LRRC4,NQO1,SCAMP5,AKR1A1,SYNPR,FCHSD2,SLC1A1,KCNJ2,ATP6V1G1,RPS17,SH2D5,RPS5,JAK2,CHRM5,ZC4H2,GPHN,STAU1,SSPN,CHMP2B,SRC,HRAS,SLITRK5,CACNB2,RPS20,NTF4,RPL15,HNRNPH2,GNA11,RPL6,RPS28,KCNH1,YWHAH,ASCC1,MAP1B,FLOT1,ATP1A1,SARM1,IGF2BP1,SLC1A3,KCNJ3,UBE2L3,KCNMB1,SIPA1L1,OPHN1,SLC35G2,EEF2,KCNIP2,LRP6,EXOC3,NCSTN,CLSTN3,GRIA2,AKAP12,RAB5A,NPR2,NOS1AP,STK38,GRIA1,EIF3D,UCN,FXYD6,RAB33B,TNR,MT3,EFNB1,CNTN1,CACNB4,PSEN1,RPL28,FLRT2,PPP1CC,IGSF21,LAMP5,CALY,PPP3CA,ABHD6,PICALM,STX7,CPEB1,ADD1,SNX14,PTN,LY6H,NETO1,ATP1A2,GPR176,ZNRF1,KCND2,NSG1,RPL10A,OPRM1,NPBWR1,RGS7BP,P2RY4,ATP6V1C1,GLRB,NTNG2,SEMA4C,KCTD12,GPC1,FCHO2,PRSS12,NCDN,PNOC,BAALC,SNCB,VTI1B,VAMP2,ROGDI,GABRA2,RPL19,EPHA4,LGI1,CLN8,RPL27,COPS4,MPST,SYPL1,ADORA1,RAP1A,TUBA1A,ITGA2,ICA1,USP8,SYNGR2,NINJ1,DRP2,KCTD16,FAM107A,RAB3B,FZD4,DISC1,PSMA3,DBH,SPTBN1,HPCA,CAMK2N1,PICK1,LPAR2,SVOP,MEF2C,NPTN,CDH13,CACNB3,RIMS3,KCND3,CPLX2,RPS16,C1QL1,LRRTM3,RPS26,INSYN2B,CARTPT,HCRT,RPS7,C1QL3,RAB40AL,LRRTM1,CIB2,C1QC,LRRTM2,RAB3D,GABRG2,CPLX1,ATP6V1G2,SRSF10,SDCBP,EZH2,KCNMA1,STX10,SLC8A1,UBE3A,NLGN1,RAB11B,OLFM2,DNAJC5,FAM81A,HRH3,PDLIM4,CPSF2,CHRM3,EIF5B,HRH2,UBA52,RPS4X,HTR1A,VPS54,NPY,CACNG3,SLC6A4,SYP,RASGRP2,RPS13,NEFL,WASL,GNG3,HOMER3,EIF4EBP2,COMT,PCDHB13,SYNGR3,SYNDIG1,PKP4,GABARAP,KCNA3,ELAVL4,RPS3,RPL23,RAB6B,RAB11A,HTR5A,OPRK1,PLP1,INSYN2A,PRNP,RPL7A,SLC29A1,CTTN,GHRL,EPS8,MECP2,TMEM108,CLU,VAMP1,FZD3,ZMYND19,PLXNC1,CD2AP,ZDHHC15,RGS10,KIF3B,EXT1,SNAP91,SCN2B,SEPTIN6,COPS5,YWHAG,GRIK1,RAB13,SLC6A2,TAC1,RAP1B,KCNJ11,ATP8A1,PSEN2,FLRT3,KPNA1,SLC6A3,BACE1,USP14,GAD2,RAB3A,CHRM4,PAK5,STXBP1,TMUB1,ARFGAP1,MACO1,CDK5,DLGAP4,PRRT1,SLC35F1,RPL13A,SYNGR1,IGSF11,RPL26,HOMER1,ADGRL3,STK38L,VPS18,GDI2,CRYAB,SLITRK1,DAPK1,VAMP7,PAFAH1B1,ACTB,ARPC2,RPL22,TUFM,GABRA1,CTNND1,ARF6,DNM2,GNAI2,RPL8,CNR1,DRD1,ELK1,PLCB1,FABP5,ARL6IP5,SLC16A1,MOB4,PHB2 |
| 3.473e-11 | -24.08 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | REACTOME pathways | R-HSA-975956 | 99 | 63 | 10285 | 3229 |
RPL10L,RPS13,RPS27A,RPL27A,RPLP1,RPS4X,RPLP0,RPL13A,RPS29,RPS26,RPL15,NCBP2,RPS28,RPS17,RPLP2,ETF1,RPS5,RPL8,RPL28,RPL7A,RPL23A,RPS14,RPL35A,RPL24,RPS16,RPS24,FAU,RPL32,RPL3,RPSA,RPL6,RPS20,RPL37A,RPS9,UBA52,RPL7,RPL4,RPS12,RPS2,RPL27,RPS23,RPS11,RPS27L,RPS7,RPL26,RPS10,RPL39,RPL23,RPS15,RPL10A,RPL29,RPL10,RPL35,PABPC1,RPL26L1,RPL19,RPL22,RPS3,RPL17,RPL31,RPL9,RPL18,RPL12 |
| 3.539e-11 | -24.06 | P4HB (prolyl 4-hydroxylase subunit beta) | protein interactions | 5034 | 394 | 171 | 19454 | 5460 |
SLC25A24,RNF8,PPME1,MINDY3,GPX7,SURF4,HSPA13,CD2BP2,H2AX,MAP1LC3B,UBL4A,CAPZA1,VWF,EDEM2,WASL,DNAJC30,HSD17B10,IGF1R,BCAP29,ERO1A,TNFRSF14,UBXN10,COPS5,HDAC6,FAM20C,EDEM1,ZNF24,CALR,DPP4,ZBTB2,CWC15,CDK9,TMPO,LMAN1,TOP1,PRNP,DNAJC1,TMED9,LDLR,PLCXD3,COX4I1,EFNA3,PTPN1,UBE2M,HEXIM1,FGFR1,METTL14,HSP90B1,P3H1,RPA2,CFTR,UQCRC1,GABRA1,RPS14,PSMC4,HSPA5,PDHB,ACP5,ARHGEF6,PML,SIRT7,BAP1,RPA3,SOD1,COL1A2,CALU,UBE2H,DNAJC10,LGALS8,RC3H2,ATP5F1A,SEC63,VIRMA,GARIN6,KCTD9,MSN,GANAB,ENO1,NECTIN2,UQCRC2,GXYLT1,PLD3,PDHA1,CHMP4C,EXOSC3,EZH2,SOX2,DNAJC25,MED9,CSNK1E,B3GNT2,RAF1,SAR1B,IMMP2L,TRIM37,CHCHD2,PDIA6,EWSR1,PCNA,PABPC1,HSPD1,YWHAB,PEX3,HNRNPD,AGR2,NCK1,GSTO1,CTNNB1,ATG7,HNRNPA1,PPFIBP1,YWHAG,NOL4,PPIB,PDIA3,CCT7,HSP90AB1,NDUFS8,DIRAS3,SUMO2,DNAJB9,EIF2S1,FEZ1,PHB1,CNDP2,PPT1,ACAA2,PSMB7,NEK7,EDEM3,SEC62,PXMP2,STAU1,UCHL3,UFL1,PTN,EMC1,PSMA3,STK26,PMAIP1,AKAP1,P4HA2,CD1D,HDAC5,TXNL1,HSPA8,TIMP3,TMEM106B,CXCR4,DDX39B,DNAJC3,SERPINH1,PFDN2,HSP90AA1,MYO6,BRCA1,BAG3,PDE4B,CUL2,PSMA4,GRB10,CUL3,MYC,CLIC4,APEX1,ESR2,USP5,ACTB,ATP5F1B,EIF4A2,SEC61B |
| 3.556e-11 | -24.06 | HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1) | protein interactions | 3187 | 1539 | 545 | 19454 | 5460 |
MRPS9,UBE2N,IER3,CACNB3,CAND1,CPNE1,TMED9,FAM156A,FZR1,MIRLET7G,SNN,MIR429,MBD5,DPP4,CD81,API5,ELOC,SHC1,NUS1,MIR9-3,DHX9,NEDD8,HNRNPK,MEPCE,MIRLET7C,STRBP,MVD,TP53,KIF1C,GPR162,GNPNAT1,DDX42,CCM2,NUPR1,CYTH1,STAT5A,THAP8,RNASEH1,EIF4H,EGLN2,DYRK1A,AKT1,NUDT1,CFL1,MTPN,UBE2H,ALKBH5,RBM7,BAP1,IRF3,NME4,ADAMTS10,UGP2,MIR34B,ELFN1,FBXL19,CD2AP,CDC42,WWP1,MIR7-1,RAB31,CCDC71,RAB35,FUBP3,WDR82,ZNF740,ECHDC1,HNRNPL,SMUG1,MIR9-1,SUMO2,AASDHPPT,SNRPD3,PEG10,IFI16,WWP2,RAB5C,SELENOW,YWHAG,XPO1,DDRGK1,RIMKLB,AK2,NCK1,CRTAP,MIR31,DDX1,MIR221,ARMC8,MAGOH,LSM14A,MIR9-2,MIR206,EWSR1,FAM168A,HNRNPF,NAB1,RPS4X,PRPS1,IMPA2,TRMT1L,GCLC,TMBIM1,MIR222,SPG21,EEF2,PLS3,VEGFA,DDIT4,DLST,CMTR1,DLG4,PRMT5,MIRLET7B,SMU1,MATR3,PCMTD1,APEX1,NCKAP1,EFNA5,MYC,ST3GAL2,HNRNPAB,LDHB,HNRNPC,BTF3,SNRPB,STX16,CCT2,MRPS25,FBXW11,PSMD14,CRMP1,OAZ1,SERPINH1,SMARCD3,PEBP1,VSIR,DDX5,RAMAC,UFL1,TRA2B,ZNF692,ADRB2,PACSIN3,MTF1,LMO3,PPT1,EIF4B,CAV2,EFNA3,MIR25,TSR2,CHID1,DCUN1D1,CDK9,NCBP2,ATP1B1,MIR34A,NPR2,FAF1,RAB1A,NKRF,EGFL8,HUWE1,DNAAF10,SMN1,TOR3A,FBP1,TRIM6,ADORA1,CCT5,MTARC2,MIR15A,TAF1D,SEC14L1,TNFAIP8L1,ACTR2,RNF121,DHRS7B,CCNF,MRPL53,CTTN,TRIM27,GTF2A1,MSN,NDN,VIRMA,GNAI2,TAF5L,CIAO1,FBXO7,BAHD1,RPA3,INPPL1,RHOU,MIR205,GID8,MIRLET7I,SPCS2,MIR34C,YKT6,MIR7-3,CXXC1,TMUB1,COQ8B,PIP5K1A,CDK7,CTDSP1,PICALM,METTL14,ZCCHC17,HNRNPH3,RARS1,CARHSP1,WTAP,ZNF664,MIR7-2,MRTO4,MAP1LC3A,AZIN1,DHX15,PDIA3,HNRNPA1,TMEM30A,HNRNPD,MED4,ST3GAL4,PDAP1,HSPD1,HNRNPA2B1,BCKDK,ENKD1,IMMP2L,AHCYL1,SAR1B,ANP32A,BUD23,B3GNT2,GABARAPL1,ACTN4,NFE2L1,DIPK1A,AQP3,NME1,CHMP4C,NDUFS6,JPT2,BMP1,TENT5C,MIRLET7D,ERH,ACO2,NIBAN2,PYCR1,PKP4,MIR98,MED10,BRCA1,DCAF4,RHOB,MIR363,LSM14B,HTRA2,FAM219A,DUSP9,FAM168B,BIRC2,CFDP1,PPP2R2C,CSRP1,INPP5E,PGRMC1,CEND1,ELFN2,NUDT3,VAPB,IER2,FKBP10,SYNCRIP,CD4,TMPO,KLF9,CD99L2,CDC5L,SURF6,ADIPOR2,COPS5,ORMDL3,MZT2B,SNRNP70,SNIP1,MIR200A,TCEA2,RAB13,STX18,ERO1A,MAN1A2,TRAFD1,KPNA2,TMEM33,PHYKPL,MIR16-2,UBL4A,TCIM,LBH,ZMYM3,TAB2,SLC1A1,KCTD9,SMURF1,NAA50,MAT2A,MORF4L1,MED22,PTPN11,NCAPG2,SPOP,RC3H2,RRP7A,MIR10B,HNRNPH2,RNF113A,UBE2K,EIF4E,TOMM20,MIR29A,HSPA5,MIR107,BLCAP,PPP1R8,NEK2,CFTR,RPA2,ZNF326,CLIP3,HEXIM1,UBE2M,MIR21,MIR612,LAPTM4A,GNB3,SPRN,SDC4,HOMER3,SRSF1,MAGED2,EED,MIR214,GSTCD,FAM98A,ELK1,MACROD1,HMG20A,MIR143,MIR29C,ZNF345,NT5C2,FOSL2,FKBP4,AGR2,HSPB1,MIR140,PABPC1,SDHC,RTCB,SPTSSA,TRIM11,ZNF609,GJB1,MIR155,HNRNPDL,MAX,RANBP1,TRAF2,HILPDA,CRTC2,TNPO2,TPPP,UCK2,HDAC11,SV2B,RND3,AAMP,SF3B4,BST2,SNRNP40,TOM1L1,GFUS,PBLD,HMGCS1,COX11,BEX3,LAMTOR1,RBM27,ICAM1,POLR1B,FAXDC2,DNAJB6,ARG2,APPBP2,AKAP1,GABBR1,HNRNPA0,UBE2D3,ARHGEF39,STAU1,ZBTB5,MRPS7,RPL27A,TANK,CD59,VAMP1,PALS2,PIH1D1,MIR106B,RCHY1,UBP1,PWP2,ARF6,PRNP,CIDEB,GMPPA,EMC4,HDAC6,CD9,DNAJC7,LTBR,GLUL,UNC50,RING1,SEPTIN7,HAPSTR1,APH1A,OLA1,MRPL22,CCDC47,YTHDF2,EEF1A1,MIR200C,MLLT6,MIR17,JOSD1,MIR20A,UBE2B,ILF2,RAD23B,MIR16-1,EIF4A3,TMSB4X,SNX12,GANAB,CFAP298,UBASH3B,YES1,TENT2,VKORC1L1,DDAH2,PYCR2,RUNX1,PPP1CC,USP14,NONO,AR,MIR145,NCKIPSD,HOXC4,GTF2I,CERS2,DGCR8,PFKFB2,NUCKS1,NHP2,MBD3,AATF,RBFOX2,SAP30BP,CCND1,MIR1-2,EIF3J,HACD2,LMNA,HSP90B1,OXSR1,PITPNA,FOLR1,WDR6,PHB1,PPP2CB,RPLP1,GATD3,MIR141,CCAR2,PRPF19,DPY30,CREBL2,TRA2A,CHST11,AHSA1,MIR1-1,PPP3CA,AKT2,SLC39A7,ERP29,TRIM26,RBBP7,GNL1,TRIM37,DMPK,SRSF4,RFC2,GNG3,RBM38,GNB1L,RBPJ,CYB5B,SSBP3,VGLL4,RAN,SERINC1,TMCC1,GNB1,TNPO3,CUL3,CUL2,OTUD7B,RHEB,NTF4,WDR20,LMNB1,PFDN6,TSPAN15,NMRAL1,CRY1,HADHA,MIR106A,G3BP2,WDR77,ALKBH3,PPP1CB,LRTOMT,TIMM13,LMO4,PPARG,VAV2 |
| 3.575e-11 | -24.05 | localization | biological process | GO:0051179 | 4474 | 1493 | 18204 | 5365 |
NUF2,RAB14,SYK,STX11,SELENOT,ZC3H11A,ZDHHC17,TESC,S100A8,LIN7B,ODR4,NAIF1,UBAP1,YKT6,LAMP3,RHOBTB1,RAB33B,RAB5A,PRPF31,USE1,SLC12A2,STX6,XRCC5,FEZ1,DPP4,TRMT10B,VPS54,VAMP3,SLC35B3,ARL6,ARL2BP,TUBB,TRAM1L1,CBLN4,IGF2BP1,CLEC9A,TIMM8B,SLC16A10,OLFM2,LAMTOR3,LRP10,CHTOP,THY1,STX18,PMP2,TFEB,TRAPPC2L,PARP11,HIKESHI,UTP25,RAB22A,NLGN1,CACNB2,ARFGAP3,ATP5PB,PIK3CA,CD47,SLC13A5,PHAX,SYT2,ZFAND2B,THOC1,P2RY12,COMMD9,STX10,ROCK1,GPIHBP1,TERB2,MIR301B,BSCL2,YWHAZ,TPD52,SLC6A6,WDR19,PIK3R2,SRP72,AGK,NDUFB8,CAMK1,BICD2,FZD4,PRELID1,SEC62,PPM1K,FXYD6,SNX24,CTSA,VEGFA,BORCS7,AIFM1,CEBPE,WNT7A,ARFGAP1,FKRP,TSPAN10,SLC25A31,SLC35F1,FUBP3,TMED4,SNX18,NFKBIA,KICS2,OXTR,DYNC1I2,RAB3D,RHCE,BAK1,VDR,MAP1B,SLCO1B3,XBP1,KCNK17,BUB3,LHFPL4,SOD1,LAT2,CCND1,PAK2,KCNH8,NRP1,PCSK9,PIP5K1A,KCNK13,ATP5MC1,PRKCE,CPLX2,CA2,MIA2,SPRY1,SNAP29,LMNB1,CLIP3,SLC6A12,IMMP2L,MACIR,BORCS6,BBS5,THOC6,LRRTM1,GLTP,CETN2,ASPM,CHMP1A,DDX39B,GNAO1,UQCRC1,EIF4E,AHCYL1,ID4,KCNMB2,ZBTB16,OCIAD2,ATG7,FAM53C,HDAC3,TNIK,TIMM17A,NACC2,HM13,DNAJB6,SFN,SYT4,AQP11,EHD4,PEX5L,SAR1B,TXNIP,SMYD3,PAX6,SCAMP2,TP53INP2,SLC35C1,PRKAG1,OPTN,PNPLA8,CHMP2B,CLDN4,ARL4D,GOLPH3L,KCNMA1,CDK5,FGF7,SEC22A,RANGRF,MYO1B,SLC22A17,CHRDL1,SNX22,SMDT1,PITPNA,RNF5,ATP6V0E1,TBCCD1,PPT1,MUL1,RANBP6,VAPB,ING1,RPA2,ERLEC1,ANP32A,TESPA1,EXOC3,RP2,YWHAB,ARF6,ORAI3,CASC3,H1-5,CDKN1A,MDFI,TOMM20,GPR89A,SLC22A12,NUP35,TMEM107,TRAPPC6A,SNX20,HSPA8,SLC15A1,TRAM1,ZNHIT3,ACKR3,RAB30,NUP42,DLG4,CER1,CLCA1,STARD5,UQCRH,MAP1S,SPCS3,TP53,SDCBP,MDM2,SLC25A39,NCBP2,GABRA1,SSR1,KIF3B,HOMER3,FYTTD1,SLC25A12,MLC1,S100A6,CDKN1B,BET1,RBM15B,SLC15A2,CHMP4C,SCFD1,RAB3C,CDAN1,CYP27B1,GPM6A,SLC35D1,SLC51A,SNX2,GABRA2,KPNA2,HEXB,SLC22A6,FAF1,VAMP8,RAB1B,KXD1,NAPG,SLC7A8,GAS8,RAB3B,TOMM22,C9orf72,MCM8,TVP23B,ZNHIT6,SRSF7,ELMO2,ADRB2,THOC3,CCR7,ZFAND2A,LRWD1,SYNGR2,LRP3,PPFIA2,ALB,SLC35F2,CD209,EMC4,JAGN1,GJB2,SLC2A3,ERO1A,BAG3,NDFIP1,CBL,SOX9,VTA1,GHRL,EMC1,RAB3A,KLC2,DLG3,NAPA,LRRC8C,CYTH2,PRPF19,NR1I2,CSE1L,FKBP1A,VIPAS39,SKA3,SLC66A2,SYNGR1,IRF8,MRC1,CCR1,RAB9A,NDUFS8,HNF1B,NXT1,OPRM1,C1QL2,SLC48A1,STK3,CFL1,DDX42,UBAC2,ABCB9,FCHSD2,CCL5,KCNB1,SOCS2,MTMR6,SLC6A2,FLCN,ARFIP1,NDUFC2,IFT22,CYTH1,MDC1,FXN,ATP5PO,FAM98A,CCDC186,CSNK1G3,CPTP,COG1,SLC25A17,RUVBL2,AP2M1,UBL4A,RALB,KCNG3,ZDHHC4,FCHO2,ACTR1A,NDUFA5,FCGR2B,PHYHIP,CD63,GPAA1,PLP2,ATG16L1,SLC7A11,SEC63,SELENOK,NXT2,ESAM,CRHBP,EIF4A3,PLSCR4,RILPL2,TMEM108,NLGN2,TICAM2,RAB19,ARMC1,ESYT1,PACRG,CCL19,SYBU,SLC25A44,MRPL18,PRSS12,IGSF11,TESK1,KCNJ8,LAMP5,SRC,ADRA1A,SLC25A46,CDK20,ANGPT1,PPID,EXT1,SRGN,PLCB2,PSEN2,ATP5MC3,ZMAT3,BIRC5,SLC39A3,STX5,TOM1,HBA1,MEF2A,ARL4A,SLC25A32,SLC30A5,DNAJC5,SNCG,SNX1,SHOC2,BLOC1S5,RGP1,SCG3,TMED3,ACTR2,NBN,STARD4,AP3S2,NTRK2,MAIP1,NDC80,MECP2,SIGMAR1,EMC9,AKR1C1,SNX17,MIR29A,BNIP3L,SYS1,LYPLA1,SLC41A1,TOMM6,MIOS,TBC1D4,LMNA,FAM53B,SELENOS,DRD3,UBXN6,FTHL17,GABARAP,VAMP1,NPC1L1,TMC7,BOK,AP1M1,RAB5C,VDAC2,IFT25,SLC1A2,H2AC4,TIMM8A,ENKD1,ADRB3,SNX12,RIC3,ATG4C,SLC7A4,ARRDC3,TOR1AIP2,SKP1,NCALD,TSPAN15,ATP8A1,BCL2L1,STXBP1,BAD,GRID1,DERL1,SSX2IP,KPNA6,FAM91A1,RAMP3,GSK3A,SPTSSA,CNNM4,HSPD1,CPLX3,AP1G2,ROPN1B,VDAC1,KCNA2,VPS33A,FLOT1,UPRT,SLC1A3,SERPINA5,DUOXA2,UBE3A,DPP10,COPE,MYO6,KCNF1,PEA15,STOML2,DYNC1I1,CAMLG,UBB,EXOC1,TIA1,MFN1,SLC38A7,ABCC2,SEPTIN6,ILDR1,RTN4,CD9,AQP4,SLC35A2,AQP2,BCL2A1,SLC25A42,VAV2,RRAGB,CHMP2A,SIN3A,SNAPIN,EPHA2,STX1A,CORO1C,MFSD3,STXBP6,AGER,PLEKHF1,RHOB,S100A10,PREB,ROCK2,TMEM50A,APPBP2,ADIPOQ,PLAAT3,CNTNAP1,SNX14,TMEM106B,HRH3,MRGPRX2,CFTR,SCN2B,DDR1,SLC22A8,RAB9B,EXOC5,SLC29A1,EXOC8,JPH4,BORCS8,CIDEB,ATG3,TIMM23,PLEKHA8,PSMD10,ATAD1,RPF2,ANKH,LGI1,TRIM23,FBXW11,SPCS1,SLC35E4,PLEKHJ1,SGIP1,SCAMP5,ICA1,TMEM87A,AZGP1,GHITM,LRRC8A,TRIM27,SLC4A10,NETO1,MADCAM1,GNPTG,SRPRB,BLOC1S2,TAF7,VPS4A,SLC39A7,CLEC7A,STX12,CETN3,JUP,SLC35E3,RHOJ,TSPO,RAP2A,GLE1,OSTM1,YIPF4,RAB39B,RPL23,LIPA,LIN7C,RACGAP1,CYP7A1,ANKRD50,SLC17A5,COX5A,AGAP1,RAD21,CNTN2,CLN8,SLC6A4,TPBG,RAB32,ATP5F1E,CHRNB2,OSBPL8,CEP41,SLC25A11,FBXO22,MREG,HSBP1,PEX13,NDUFA1,TRIM37,TMEM115,TOM1L2,VPS4B,AP5S1,CDH13,TIMM10,FOLR2,SNX33,CRYBA1,FCN2,CHP1,PLSCR3,SLC7A14,SLC6A3,KLHL12,RIMS4,CPT1B,EMC2,SEC22B,ATP5F1B,AP5M1,ARL5B,CTNNA1,SLC30A7,CCL21,NDUFA2,HYCC2,ATP1B1,SLC35A5,RIT2,MACROH2A1,HPS6,ATP2B4,MAD2L1,EDEM1,MFSD14B,RAP1B,SLC25A24,CHGA,CTBP1,PRKCB,HTR2A,INPP5K,MARCHF5,APLN,PSRC1,REP15,WDR45,MAGED2,SNAP25,NDUFA12,HSP90AA1,SYNDIG1,CLBA1,PMPCA,TMEM50B,THOC2,SEC61G,WWP2,HNRNPA1,DNAJC19,ZNF207,PEG10,ATP6V0B,SLC20A2,SLU7,ZFAND6,G6PC3,SNCB,TOMM40,CREB1,FRMD8,TUBA1B,IER3,TMSB10,IFT57,SNX3,WWP1,TNPO3,CRB3,ZMPSTE24,AP2A1,ATG9A,LILRB4,EGR2,ARL6IP5,VAMP5,SMG5,LDAH,SLC20A1,ACHE,STARD3NL,ATP6V1A,LCA5L,CAV3,FKBP1B,SLC25A45,TAX1BP1,DERL2,SCG5,ARFGEF1,TMED9,STK11,STX16,SGF29,HDAC6,SCN3B,XPO1,ATRAID,SCYL2,SPTBN1,CD2,SLC2A1,NPC2,TIMM13,STAR,LACRT,YES1,SLC23A2,ASIC1,NUP37,VMP1,FKBP4,GLRB,SNAP23,HBE1,RNF26,BPGM,NPTX1,STAT5A,VIP,PPIF,YIPF5,PICK1,NUP62,EXOC2,EHD3,WBP2,NHERF1,NGB,SLC16A4,CLCN6,SYNGR3,SYP,ATP5F1D,DRD1,PIH1D1,CACNB4,CHRM3,WRAP53,GTF2H2,NDE1,NDUFB10,SLC6A11,PIK3CG,HNRNPA2B1,NECTIN2,FASLG,INSIG2,ABCG2,NDUFS2,CDC23,NUP107,PAFAH1B1,IFT52,TIAM1,MAGOHB,STAU1,NEO1,SURF4,IPCEF1,KCND3,CPLX1,NDUFS6,ACAP2,RAN,PIK3R1,CCDC47,MTX2,ATP6V1E2,CUL3,NR0B1,GORASP2,CRYM,CCNB1,BET1L,TIMM21,SLC52A3,TCP1,STX17,NIBAN2,STIM1,AP2S1,FABP5,EMC8,NDUFB4,LAMTOR2,PRRT1,SLC38A2,AKT1,KCND2,IL1B,SLC45A3,PPP3CA,SLC6A1,VPS39,SLCO3A1,AGR2,ABCB1,ATP6V1G2,NSG1,CALR,ROMO1,DKC1,UCP2,ENY2,RFTN2,SLC18B1,MT3,ATP5PD,NUDCD3,TNFAIP3,GSTP1,TXN,RHAG,SLCO2B1,KIT,CYB5R4,TSPAN5,FHIP1B,CPE,MET,TOLLIP,SYNRG,LMBRD1,TGFBR2,SLC25A26,PLA2G5,TFG,TSG101,KCNS1,LASP1,SYVN1,SLC25A10,TMEM88,MPV17,SLC37A4,TMED1,ERRFI1,VPS26B,AKT2,EMC10,CDC42SE1,FAM149B1,BVES,MIR130B,OXSR1,CALHM5,KPNA1,DDX1,FCER1G,SLC7A1,ZDHHC14,ARL11,SLC2A8,RAB23,DNAJC27,G3BP2,ACVR1C,GPM6B,CEP19,ACAA2,NOP58,HEXA,TRAF3IP2,RTP4,BAX,GP9,LAMP2,TOM1L1,IL6,EFCAB7,MCL1,KCNIP3,LEPROTL1,PLCB1,MLLT6,PPP1R10,FABP4,GRIA2,DSN1,RHBG,SLC39A9,SLC35E1,EDNRA,XPOT,TRAPPC3L,VPS18,TAPBP,PIGW,HFE,CTDSPL2,RAB11B,BCL6,RHOU,NSFL1C,ELMO1,TOPBP1,SSR3,TBC1D24,ARHGAP12,FITM1,HINFP,COX4I2,XCL1,ACTB,GRPEL2,TNF,AVPR1B,SLC25A4,SEC13,ATP1A1,GJA1,SEC61A1,CKLF,MIR17,MAPKAPK3,SLC25A27,AIF1,TMSB4X,CDK9,RAB37,FOLR1,TBC1D10C,RSRC1,SLC25A5,IK,CITED1,LRRC8D,RB1,RAB31,GHR,LARGE1,ARHGAP1,ITGAV,ANO3,CRABP2,TMEM38B,TMEM165,SEC14L1,ARF4,TLR4,RPS15,RPAIN,ZBED3,TMEM14A,HOMER1,TMED7,TOR1B,PIP4P1,TMEM147,STK4,SLC7A9,PPFIA3,SSR2,LEPR,CNP,EHD1,SKA1,RHCG,SYNJ2BP,NDUFV2,SOST,MAPRE1,SUFU,CHMP5,TNFAIP8L3,APOO,CD3G,CDO1,SGTA,SLC16A1,SV2B,FCMR,APOC2,SAMM50,IPO8,CYB5R1,GPHN,B2M,DHX9,RABL3,CMTM6,ATP6V1C1,PPY,SLC31A1,RNF167,ISG15,NEDD8,HRH2,OSBP,ATP5MG,LCA5,KCNMB1,HYCC1,FBLN5,GJB1,RAB29,GABRG2,OLR1,CCR5,RAB13,CHST11,KIF1C,DLG1,SLC25A14,TRAPPC3,TOPORS,BECN1,CBLN1,POLA2,FIS1,COX4I1,HBB,OS9,SLMAP,COPZ2,SLC38A9,MIR29C,FCGR1A,RABL2B,WDR11,JAKMIP1,KCNIP2,HGS,SLC19A3,RAB28,SCG2,LILRB1,SLC6A7,ID1,YWHAH,CCL3,RAB18,ATP5F1A,RNASEK,CSF2,STX8,ATP6V1D,NDUFB7,UNC119B,RAB4A,KCNC1,ZDHHC15,TUSC3,CDC42,ICAM3,FTH1,FERMT2,IFT172,GOSR2,CSNK1E,IGF1R,RTRAF,MYD88,KLHL3,OPHN1,HSPA5,SPOP,ATP2C1,SLC25A51,CD81,TULP3,AQP3,SLC6A8,MAVS,FURIN,MFSD5,TYROBP,KCNAB1,CLIC2,VTI1B,SEPTIN7,MACROH2A2,CLU,RINT1,TMIGD1,SLC25A3,GRPEL1,TMEM167B,KCNJ10,ATG4A,SARM1,LMBR1L,CLTRN,GIT2,TFRC,TUSC2,SRP14,CYBRD1,RAP1A,VPS16,FXR2,KCNJ3,TSPO2,NDP,DNLZ,LAMTOR1,CD2AP,SLC25A20,UMPS,JPT2,GRM2,C2CD2L,RAB35,CUTA,SFTPD,PML,NECAP1,SRPRA,SLC11A2,DISC1,HCLS1,UBXN2B,SRI,FGF13,NDUFB5,TERT,SSNA1,SH3BP4,CALY,DAG1,C1QL3,MGARP,KCNJ11,SLC25A21,NME1,TM9SF4,SQSTM1,RAB40AL,LEP,PHB2,SLC25A23,SERINC3,SNX10,DYNLL1,SEC23A,CHAMP1,GOLGA5,SFTPA1,RAB8B,TMCC1,NIPA2,TRIM3,LYSET,EHBP1,ALYREF,SNX11,TOMM7,BORCS5,GOLGA7,SFXN1,COX17,FBXO7,SEC61A2,SLC38A1,TRAPPC4,KDELR1,NOP53,PHETA2,P2RY4,CALHM2,PEX26,ASB3,RNF128,UNC50,PDIA2,VPS26A,PACSIN3,CAMK2G,SNX5,CYB5A,MAGOH,PDCD10,RALA,KDELR2,SLC1A1,CTNNB1,VPS26C,HYAL2,CD14,SEC61B,GRIA1,CCHCR1,SLC8A1,CARTPT,NUP50,NUP153,TM9SF1,ATP5IF1,VLDLR,STX7,LRP6,SLC41A3,MIS12,DDX39A,APOC4,MCPH1,CYB561D2,SLC4A8,BCAP29,ABCE1,TUBA1A,RAB27A,HBM,TEX261,TOMM40L,DVL2,CRY1,AP1S2,LDLR,USP6NL,GRIK1,TRPC1,PRL,TNPO2,NCKIPSD,SNAP91,MAP4,GRM1,LRRC8B,FGR,MX2,LRRC4,YWHAG,COX6B1,NDUFB6,SEC22C,ERP29,RHOBTB3,GUK1,TSPAN17,JAK1,UBE2B,SLCO1A2,DNM2,SMURF1,EMP2,CACNG3,SFT2D2,TRAPPC1,COX7A1,CPNE1,MLH3,TRAPPC6B,TIMM29,TSPAN18,GJA10,SRSF10,LGI3,NDUFS3,IREB2,SYN3,KCNH1,PMAIP1,SLC32A1,CD36,TPT1,VPS28,EMC6,TMEM184C,CDC42SE2,CXCR1,RAB6A,HMGB1,MAPRE2,GABRB3,ABHD17A,PITPNB,HRAS,PYCARD,TRIM46,ARMCX3,RAF1,SLC39A10,CACNB3,IL10,DDRGK1,POLDIP3,COMMD3,VAMP7,RAB6B,RAB11A,RBP5,TMEM144,MSX1,RAB2A,TRAPPC10,TMEM184B,TBC1D5,LMAN1,NEFL,BRD3,KCNQ5,TBC1D17,WDR83OS,ORAI2,PLSCR1,SLC35B4,CCR2,HSP90B1,GLRA2,NETO2,SH3GLB1,CYC1,VAMP2,KCNA3,INPPL1,SPRN,TBC1D13,PEX3,STRADB,CTTN,ASIC2,ADORA1,RRP7A,CHMP1B,PLPP4,P2RY1,SRSF1,COMT,DDIT3,TOMM70,CCL8,ERCC3,SLC39A13,ARF1,BCS1L,CLIC4,SVBP,FKBP8,NOP9,TMEM30A,ABCC5,RRAGA,CXCL8,SKA2,ARHGAP21,SCN1B,CYGB,SESN2,CALHM3,GOLGA7B,PGR,GABARAPL2,TMED5,UFD1,F11R,RABIF,SPCS2,CCDC22,YIF1A,PAQR3,DESI1,ARCN1,PPARG,KCNK10,IKBKB,CHCHD4,MKKS,AP1AR,TRAK2,SRP54,PTGDS,EZH2,UPF3B,CHRNA7,EIF2D,ATP6V1G1,FABP7,SLC5A6,GCLC,SELENOM,WASL,ZDHHC24,RBP2,MARCHF3,DPY30,STBD1,TF,CPT2,FGF10,SPC24,PLA2G12A,ATP5PF,AIP,ARHGAP25,PICALM,ATP1A2,SLC35F6,TST,SVOP,ACTN4,CAV2,XPO5,TTC8,CHRM1,CCT2,RER1,H2BC11,COPS5,SUMO1,FABP12,CRHR1,RNF126,FOSL2,LRP12,AFTPH,COX8A,ATP6AP2,CDK1,KCNJ2,TRAPPC13,CNIH4,MTCH2,GDI2,CHRM5,BTF3,SFXN2,RIMS3,GLRA1,PREPL,COX7B,CASK,FITM2,SLC25A28,SLC43A2,FAF2,SLC25A1,GOSR1,SLC35A1,HSPB1,ATP1B3,SMAD2,TRAM2,BRCA1,SLC38A3,ALKBH5,GABRB2,PTN,CD4,SLC19A2,GJC1,MTM1,TNKS2,PSEN1,UBE2I,ATP1A3,CLDN1,NECAP2,TNKS,MPC1,CAV1,CDR2L,MCOLN1,FTL,SUPT7L,PLEKHF2,BLOC1S3,RAB1A,NME4,AGAP2,NDUFA4 |
| 3.716e-11 | -24.02 | PSMB2 (proteasome 20S subunit beta 2) | protein interactions | 5690 | 200 | 100 | 19454 | 5460 |
UBE2H,XPOT,PSMB2,AR,USP14,FBXO7,ADRM1,KCTD9,VIRMA,PSMA6,STUB1,CCNF,PTEN,SGTA,PSMC5,GRM2,RPA2,ACACA,UBE2M,UBA52,PSMC4,UBLCP1,CFTR,FBXW7,RPA3,SQSTM1,PGK1,SYVN1,PSMD7,PSMG2,USP15,DNAJC7,HDAC6,HM13,FZR1,ASB11,HRAS,MRPS9,PSMB1,SEC23A,UBE2B,RAD23B,PSMC3,RNF181,UBL4A,PSMB9,PSMA5,FKBP8,PSEN1,GPX2,PSME1,MAP1B,PSMD14,POMP,RIT1,PSMA4,CUL3,MYC,PSMD1,MBL2,PSMD6,TUBB,PSMD4,PSMB6,LMBR1L,PSMB7,PSMB3,NSFL1C,UFL1,SKP1,PSMC1,DDI1,PYGB,PSMA3,TXNL1,HSPA8,AGR2,PSMD10,HSPB1,RB1CC1,TST,POU5F1,PSMD3,EGLN3,PSMB5,PSMB4,FOLR1,PSME2,CHMP4C,PIR,RNF126,ISG15,CDK20,KRAS,PSMA1,PSMA2,RPS27A,UBE2A,PSMD12,UBE3A |
| 3.757e-11 | -24.00 | KBTBD4 (kelch repeat and BTB domain containing 4) | protein interactions | 55709 | 313 | 142 | 19454 | 5460 |
PDRG1,TRIM63,AKAP12,HUWE1,PC,RPL3,CACUL1,DDX39A,MTCH2,RAP1A,SNAP29,MYL12A,MIF,RPL35A,RPS16,RAP1B,AIFM1,USP15,KPNA1,CNN3,DNAJC7,EXOC2,ECD,LRRC40,MPG,COPS5,TLE1,MBD3,CHMP2B,RPL4,SMC4,KDM1A,ARFIP1,SQSTM1,RPL27,LIN7C,ACACA,UBE2M,GOLGA5,PICALM,DCTN4,CDK1,SDCBP,H2BC11,TOX4,CD2AP,MYL12B,RPS14,SAP30BP,NOPCHAP1,RPL13A,PYGM,PTEN,CTTN,PSMA6,CCDC22,CHORDC1,GMNN,KPNA6,RPS17,BRAP,RPL7A,PTPN11,CSK,SUGP1,COPS4,PFDN1,RPS4X,RPL28,RPS27A,RPAP3,PRPSAP1,PABPC1,SCYL2,ZYX,NEK9,CRKL,SNRPE,HGS,ERLIN2,NUDCD3,ARFGAP1,RAF1,SPC24,NAA15,DHX15,SLMAP,RPL7,TCP1,CCAR2,AGK,FAM98A,IGBP1,CORO1C,MAGED2,PDAP1,HSPB1,H2BC17,CTNNB1,RPL6,PSMD3,TAF7,UNC45A,NRBF2,NSFL1C,AKAP1,TTC1,HADHA,DCTN3,HSPA8,P4HA2,MYL6,PIH1D1,EIF4B,NUFIP2,KLC2,CRYAB,PGRMC1,USP5,POLR2B,MATR3,TAGLN2,PSMD4,RPS9,AP2M1,EFHD2,DNAJB6,PRSS1,HSP90AA1,RBM27,MYO6,PSMD14,CCT2,ATP1A3,BAG3,UFD1,PCCB,SAMHD1,BTF3,PRPF31,CUL3,ACO2 |
| 3.798e-11 | -23.99 | translation | biological process | GO:0006412 | 383 | 173 | 18204 | 5365 |
MRPL24,MRPL13,MRPL12,MRPS9,MTRES1,RPS13,MRPS25,EIF4E2,RPS16,ABCF1,RPS28,RPL32,EEF1B2,RPL10A,MRPL18,EIF5B,RPL6,EIF2S1,RPL24,MRPL20,QRSL1,MRPL33,RPS29,RPL28,RPL3,RPL19,RSL24D1,RPS7,MRPL34,GTPBP1,MRPL17,CARS1,SELENOT,APEH,ZC3H15,EIF1AX,MRPS18C,EEF2,RPS3,ETF1,MRPL10,RPS24,RPL23,EIF2B5,EIF3K,MRPL49,EIF1AD,RPL15,RPS11,RPS12,GTPBP2,MRPL41,EIF3E,EIF4H,RPS5,RPS26,RPL31,RPS20,MRPL47,EIF2B2,MRPL50,TRIP4,RPL9,EIF1B,MRPL51,RPL35A,RPS15,RARS1,MRPS18A,MRPS11,RPL8,FAU,MRPL53,GFM2,RPS10,FTSJ1,RPL35,NCBP2,RPL7,CPEB1,EIF4A2,RPL13A,RPL27,MRPS17,MRPS18B,EIF2AK2,PDF,MRPL9,PAIP2,MRPL36,MRPL52,MTRF1,RPL4,EIF4EBP2,PELO,EIF3G,DRG1,ABCE1,DIO2,COPS5,EIF3J,EIF2D,MRPS35,RPS27A,UBA52,FARSA,RPS4X,EIF4B,RPL26,RPL22,MRPS34,MRPL23,GFM1,RPSA,KARS1,MRPL40,SKIC8,CHCHD1,EIF3D,DRG2,LTO1,RPL29,EIF2B3,RWDD1,RPL10,MRPL57,RPL10L,MRPS23,RPS2,RPS27L,EEF1G,MRPS21,MRPL22,RPL37A,RPS23,EEF1E1,RPL27A,MTG1,RPL18,RPL17,MRPS33,EIF4E3,MRPS16,RPL26L1,RPL7A,RPS9,TUFM,RMND1,RPLP1,RPLP0,RPLP2,DHPS,EIF5A2,AURKAIP1,MRPS7,EEF1A1,MRPL11,EIF2S2,RPL12,RPL39,ASMT,MRPS28,RNF14,MRPL16,RPS14,RPS17,MRPS26,RCHY1,RPL23A,EIF4E,SECISBP2L,MARS1,PAIP1 |
| 4.141e-11 | -23.91 | ZNF346 (zinc finger protein 346) | protein interactions | 23567 | 372 | 163 | 19454 | 5460 |
MIR206,RPS24,RPL31,MIR9-2,RPS27A,HNRNPF,MIR155,MAK16,MIR222,RPL18,GLE1,XPO5,HP1BP3,RPLP1,MIR214,RPLP2,MIR141,THOC2,MIR7-2,RPS10,MIR9-1,RPL7,SNRPA1,MIR29C,NGDN,BAZ1B,DDX50,RPL6,HNRNPD,MIR221,MIR1-1,DICER1,H2BC17,MRPL18,MIR31,NGRN,SNRPA,MIR106A,STAU1,NOP53,RPL27A,MRPS18A,SF3B4,RPL37A,MIRLET7B,MRPL13,RPS9,ZNF22,MIRLET7D,RPL19,SNRPB2,STARD7,RPL35,RPF1,RPL7L1,ZNF668,MIR98,MYC,APOBEC3B,NOP16,HNRNPC,MIR363,RPS5,H1-1,NSA2,FYTTD1,ZCRB1,FTSJ3,NOA1,RPL3,RPL23A,DHX9,MIR9-3,MRPL52,MIR200A,NKRF,MEPCE,OLA1,MIRLET7C,RPS13,SRSF12,RPL17,MIR16-2,SNRPG,PAK1IP1,IMP4,MIR200C,MIR15A,H2AX,RPL15,IMP3,STRBP,KIF1C,ILF2,RNF8,SRP72,MIR17,LLPH,MIR20A,RBM34,PRR3,MRPS9,MIR106B,KRR1,DKC1,MIR429,SURF6,ZBTB2,NAT2,CAND1,RPS16,APOBEC3F,MOV10,CMSS1,NOL12,CDK12,RPS2,RPL10A,MIR34A,MPHOSPH10,RPL24,MIRLET7I,MIR34C,RPL27,MIR10B,MIR205,MIR29A,UTP23,AATF,MIR107,BRIX1,RPS15,MRPL17,FBXW7,RPL4,MIR7-3,MIR1-2,RBMS2,MIR34B,ATG16L1,RPS14,RPLP0,RPL26L1,ZNF574,ZNF770,MIR7-1,MRPS34,ZNF326,PRKRA,PHAX,RBMX2,MACROH2A1,RPS3,MIR16-1,EIF2AK2,RSL24D1,RPS17,RPL26,ZSCAN25,RPF2,ELAVL2,MRPS16,MIR145 |
| 4.145e-11 | -23.91 | RPL26L1 (ribosomal protein L26 like 1) | protein interactions | 51121 | 426 | 182 | 19454 | 5460 |
LYAR,RPS10,SRSF1,S100A8,DRG1,MAGOH,DDX1,WWP2,RPL6,RIOX2,DDRGK1,NUP42,H1-6,RPL28,RPL31,RTCB,FGF10,RPL18,ZRANB2,MAGEB10,TRMT1L,KIF2A,RPS7,H1-3,MATR3,RPL10,ESR2,FTSJ3,NSA2,H1-1,ICAM1,ELAVL4,RPS26,MYC,THAP7,EEF1G,STAU1,ZNF692,MRPS7,RFC4,FGF17,PABPC5,RPL27A,MRPL12,CAND1,RPS16,KLF9,SURF6,RPL32,ALYREF,MRPS9,SYNCRIP,TRMT10B,SNRNP70,H2AC4,TUBG1,RPL10A,NOL12,RPS2,PLEKHO1,DPP4,E4F1,COPS5,IMP4,RPL17,MEPCE,MAP1B,MRPL52,DHX9,RPL3,RBM34,DNAJC2,RPSA,MRPL47,TP53,H2AX,SRPK2,RPS3,PSPC1,FGFBP1,MECP2,ATP1B3,UBE2H,ZBTB38,RPL7A,H2AC13,WDR3,RPS15,HSPA5,THUMPD1,RPL27,BAP1,ZNF501,HEXIM1,TFB1M,CFTR,FGF13,RPL7,RPL8,RPL9,RPLP2,MRPL18,LHX2,RPL23,RSBN1L,TRA2A,G3BP1,SRSF4,FGF3,PPAN,TRIP4,RPS24,CHMP4C,SART3,RPS11,MAK16,RPL35,RPF1,RPL7L1,RPL19,ZNF22,SEC61B,RPS9,RPL37A,ZCRB1,RPS5,CUL3,RPS29,RIOK2,ZNF668,NOP53,YTHDF1,G3BP2,APOBEC3C,KLF3,WDR77,H1-5,RPL35A,ZBTB2,AKAP17A,CDK9,KRR1,RPL12,SRP14,PRR3,CRBN,SPATS2L,LSM4,OLA1,RPS13,RPL23A,LLPH,SRP72,ILF2,RPL15,AURKAIP1,APOBEC3D,TAF1D,RPL13A,RPL22,METAP2,OPTN,PRKRA,RTRAF,RPL26,FBXO7,RPL4,FBXW7,NPM3,DGCR8,LSM8,UTP23,PRPF4,CCDC106,PPIH,MRPS34,MACROH2A2,RPLP0,ZNF574,RPS14,RBMS2,KLF12 |
| 4.289e-11 | -23.87 | MRPS11 (mitochondrial ribosomal protein S11) | protein interactions | 64963 | 232 | 112 | 19454 | 5460 |
RPS26,MCAT,HTRA2,PSKH1,MRPS25,NOA1,DRAP1,CPSF2,MYC,MTG2,AUH,CUL3,PSMB6,PARL,ESR2,RPL10,RPL19,PCMTD1,RPL35,TACO1,CYB5R3,DLST,ETF1,ACTL6A,MRPS7,HSCB,MRPL57,HSPA8,EXD2,MRPS26,RPL23,SKIC8,DCAF5,TRA2A,MTRF1,RPL6,MRPS35,GATD3,TNIK,RPRD1A,RPL9,SRSF1,RPS23,PDHA1,RBM12,TPD52,NAA16,NAA15,MRPS17,IMMP2L,KRAS,HINT2,COX8A,SRSF7,HSPD1,ATP1A1,NRP1,UBE2H,MRPS16,RC3H2,RPL26,TUFM,CIAO1,MRPS21,MRPS28,SRP54,RPLP0,HEXIM1,MTRES1,KLF4,MRPS34,RPA2,SAMM50,MRPL10,RBMS2,KLF12,RPL4,PGK1,SQSTM1,TCEA1,GFM1,NOL12,RPS2,SNRNP70,COPS5,E4F1,GRSF1,DBT,SURF6,MRPS23,ZBTB2,TRMT10B,PRR3,SSBP1,MRPS9,SRP14,TAF2,GINS4,PCMTD2,AURKAIP1,APOBEC3D,METTL15,FNTB,STRBP,MRPL11,MRPS18C,MEPCE,MRPL22,FASTKD5,RPL17,MRPS33,MRPS18B |
| 4.289e-11 | -23.87 | ATF2 (activating transcription factor 2) | protein interactions | 1386 | 240 | 115 | 19454 | 5460 |
IRF2BP1,RAB14,LDHA,PRKCE,JUNB,UQCRC2,CREB1,CTTN,ENO1,GANAB,MACROH2A1,UBE2I,SPOP,OAT,ATP1A1,CALU,RAB2A,ATF4,CFL1,AR,USP14,GRPEL1,SS18,APMAP,PML,NBN,RTN4,ITGA2,HSP90B1,KRT7,GSTP1,CYC1,SUMO1,CCND1,EDF1,UQCRC1,SLC25A12,SMAD3,PTPN1,CEBPG,RB1,SLC2A1,SMAD4,CALR,TLE1,CSNK2A1,GAPDH,BACH1,HSPE1,CTNND1,ARF4,SFXN1,ERO1A,TFRC,CCT5,BATF,MLLT6,H2AX,PPIF,EXOSC8,ATP5F1B,TAGLN2,TUBB,APEX1,ARF1,VDAC2,GTF2F2,CCT2,S100A11,PFDN4,HSP90AA1,SERPINH1,CREBBP,NFYA,RAB11A,LDHB,CUL3,SFN,ATF1,PHB2,ZDHHC17,DDX39B,SPOPL,FOS,HADHA,DDIT3,EP300,ATP5PO,MAPKAPK5,TCP1,FBXO32,PHB1,KRT8,FOSL2,YWHAB,HSPB1,PDIA3,HMGA1,INSYN1,YWHAG,XPO1,CTNNB1,CHCHD2,S100A10,VDAC1,HSPD1,ATF3,PCNA,JAK1,RUVBL2,ERP29,RPN1,MAPK10,JUN,EEF2 |
| 4.563e-11 | -23.81 | KNOP1 (lysine rich nucleolar protein 1) | protein interactions | 400506 | 259 | 122 | 19454 | 5460 |
NUP50,LCA5,MIR106A,COIL,STAU1,RPS9,RPL37A,AP2M1,MIRLET7B,DLST,TACO1,RPL19,RPL10,APEX1,MIRLET7D,RPL35,SNRNP40,ZNF668,MIR98,MYC,H1-1,FTSJ3,RTCB,RPS24,MIR206,MIR9-2,PPAN,RPL31,SRSF4,MIR155,OTUD6B,MIR222,MAK16,H1-3,RAF1,CSNK1E,EZH2,MIR214,MIR141,MIR7-2,SRSF1,RPL8,DHX15,MIR9-1,RPS10,DDRGK1,IFI16,MIR140,MIR221,MIR1-1,DDX23,MIR34C,EXOSC4,MIRLET7I,MIR205,PRPF4,RPA3,MIR10B,RPL27,MIR29A,MIR7-3,FBXW7,RPL4,DGCR8,FGF13,MIR34B,MIR7-1,RPLP0,RPL26L1,MIR21,ZNF574,ZCCHC17,RPA2,LMNA,FGFBP1,PRKRA,RBMX2,ZNF330,MIR16-1,SRPK2,RPL22,RPL13A,RHOJ,IFI6,ANAPC15,RPL7A,RPF2,UBE2H,PIP4K2C,MIR145,RPL3,RPL23A,MIR200A,RPL17,SRSF12,MIRLET7C,H3C1,AURKAIP1,MIR200C,H2AJ,ILF2,RBM34,MIR17,LLPH,MIR20A,CBX3,MIR25,ARL4D,KRR1,MIR106B,SYNCRIP,DKC1,MIR429,MIRLET7G,RPS16,RPL10A,BRD3,UQCR11,MIR34A,NOL12,RPS2,SNRNP70 |
| 4.572e-11 | -23.81 | negative regulation of cell migration | biological process | GO:0030336 | 381 | 172 | 18204 | 5365 |
DUSP22,MIR640,CERS2,CX3CL1,MIR1298,MIR24-1,MIR101-1,BRMS1L,RBBP7,MIR505,ADIPOQ,TNF,STC1,ING1,DUSP1,TMIGD3,MIR145,CX3CR1,CCN3,CXCL12,HMGB1,CORO1C,MIR205,MIR495,ADIPOR1,DUSP10,STAP1,RHOB,MIR361,NOG,EMILIN1,CCL2,NHERF1,MIR424,MIR491,MIR16-1,MIR338,CYP1B1,GADD45A,CCL25,MIR214,GJA1,CDH11,CSNK2B,TRIB1,AIF1,DPP4,CLDN3,SVBP,CLIC4,BMERB1,MIR188,MIR133B,MIR15A,MIR34A,MIR1-1,GPR173,SYNJ2BP,MITF,TNFAIP6,CYGB,RAP2C,ADORA3,ADORA1,DAG1,VASH1,MMP28,RNF41,THY1,CD200,KRIT1,MIR140,KLF4,MECP2,BMPR1A,MIR137,NFE2L2,MIR638,MIR335,ABHD2,OSBPL8,NF2,MIR29A,TIMP1,MIRLET7G,ADGRG1,BRMS1,JUP,STK24,MIR193A,RAP2A,RNF20,MIR493,PTGER4,MIR551A,MIR212,PPARG,MIR503,CXCL13,MIR218-1,CALR,DUSP3,SPRED1,PDCD10,DPEP1,SAP30,MIR9-1,HYAL2,RBBP4,STARD13,AKT1,COL3A1,WASL,MIR182,RAP2B,GREM1,ADTRP,MIR152,MIR92B,CCL28,BST2,PTEN,MIR29C,CD200R1,ATP2B4,MIR200C,HDAC5,SAP30L,MIR206,MIR320A,MIR20A,CCL21,MIR492,MIR497,STK26,MIRLET7B,MIR130A,MIR221,MIR3173,EPHA4,MIR185,ACVR1C,MIR223,GNRH1,MACIR,PADI2,SFRP1,MIR126,ABHD6,MIR379,TP53INP1,MIR885,DDT,MIR132,MIF,MIR449A,MIR10A,TMEM196,MIR204,SIN3A,ING2,MEF2C,MIR129-1,MIR31,RGCC,IL4,LDLRAD4,PLCB1,MIR146A,MIR21,IGFBP3,MIR149 |
| 4.598e-11 | -23.80 | SNIP1 (Smad nuclear interacting protein 1) | protein interactions | 79753 | 415 | 178 | 19454 | 5460 |
SSRP1,SRSF4,PPAN,ARGLU1,SLC25A5,RPS24,SRSF8,SRSF7,EZH2,TMEM14B,SF3B5,RPS11,RAF1,CSNK1E,RPL29,PPP2R1A,RPL7,BUD31,STK3,DHX15,SRSF10,PRPF19,TRA2A,G3BP2,CCDC86,SLC25A3,MFAP1,ACTL6A,RPL35,ERH,RAN,RPS9,SNRPD2,SNRPD1,CFAP20,RBM15B,SMARCE1,THRAP3,OLA1,TCOF1,NKRF,H2AC25,FAF1,RPL23A,KRIT1,MRPL49,TOPORS,MRPL11,H2AJ,SMAD1,CWC15,MRPL24,KRR1,BRD3,UQCR11,GTF2E1,RPL4,AATF,PIAS1,PRPF4,DVL2,JUP,TOX4,MACROH2A2,HNRNPH3,NOL7,ZNF574,SF3A1,RPS14,EZH1,EIF4A3,CTTN,ALB,UBE2I,CASC3,PPIG,PEA15,SMAD2,TUFM,RUVBL1,HNRNPF,RPL31,RUVBL2,RPL18,SMARCB1,ZRANB2,FAM136A,MAX,PAIP2B,SNRPD3,SNRPA1,PAIP1,FAM98A,GYS1,SRSF1,DRG2,MAGOH,ANKRD50,RPL6,ZCCHC10,DDX50,UTP6,NGDN,YWHAG,EMC1,PSENEN,TRA2B,SAP18,SNRPA,EP300,HSPA8,SF3B1,TMEM184B,NUFIP2,ZC3H14,SNRNP40,ZCCHC7,MATR3,ESR2,POLR2B,ZMYM2,FTSJ3,RCL1,HNRNPC,CREBBP,MYC,SNRPB,CPSF2,BTF3,CDC40,RPL17,MEPCE,SRSF12,ZNF451,SNIP1,RPL3,CCM2,IK,DDX42,ESS2,NKAP,FZR1,CDC5L,SURF6,RBM42,NDUFB4,RPL32,CDK6,SNRNP70,SMAD4,RPL10A,RPS2,RBM17,ENY2,GAPDH,RBM22,WDR3,AIF1,RPL27,SNAPC1,RNF113A,SDCBP,LDHAL6B,UTP15,TFB1M,SUMO1,IFI6,SRPK2,RSL24D1,PPP1R10,SF3B6,PSPC1,MACROH2A1,RBMX2,RPL7A,RPF2,H2BC9,ANAPC15 |
| 4.632e-11 | -23.80 | positive regulation of apoptotic process | biological process | GO:0043065 | 550 | 233 | 18204 | 5365 |
CCL5,PEA15,ACVR1C,IL12B,MIR200A,TLR3,AKAP12,IL6,FLCN,SFRP1,TP53INP1,MYC,BAX,NUPR1,GADD45G,UBB,MMP9,DAPK1,BTG1,CDC42,JUN,CCL3,MIR186,FRZB,RNF122,PDCD5,TPD52L1,LILRB1,MIR132,HTR2A,BCL10,HSPD1,IL12A,CD274,MIR449A,CLIP3,TMEM196,PRNP,TRAF7,STK3,DAPK3,CDK5R1,MTCH2,CAV1,IFNB1,EEF1E1,WNT10B,TXNIP,MIR204,MIR210,PMAIP1,TNFAIP8,CASP12,MEF2C,ATG7,DNM2,TNFRSF1B,HTRA2,RGCC,TIA1,MCL1,GADD45B,MYBL2,ZBTB16,IGFBP3,MSX2,MIR375,NACC2,ARL6IP5,MIR146A,PSEN1,MIR21,NOTCH2,SRPK2,PTRH2,CERS6,BOK,TGFB2,MIR675,CRYBA1,BAK1,VDR,HYAL2,CTSK,CTNNB1,LTB,NCK1,PNMA5,CALHM2,TGFB3,AIFM1,TLR6,SMAD4,RPL26,JAK2,MIR29C,PCSK9,ING5,B4GALT1,MIR125A,PRMT2,IRF8,LTA,TEX261,G0S2,BAD,MIR320A,HTRA1,CTNNA1,FAS,MLLT11,MIR221,FIS1,PAK2,LTBR,BECN1,UBE2M,CNR1,SOD1,LPAR1,TNFSF10,TP53,CTSC,IFNG,SERINC3,IDO1,STK4,ERCC3,PRKRA,MIR1-1,PDCD4,ITGA6,MIR15A,SOD2,MIR34A,SAP18,FAM162A,MIR26B,TNFSF12,PNMA1,PPID,CSRNP3,TRIM35,SRC,BACE1,TLR4,SQSTM1,CD40LG,LEP,FASLG,DDIT3,MIR140,TFPT,ATF4,MIR137,MIR28,SIAH1,PRELID1,RBCK1,CD248,MIR195,FAF1,CCAR1,MIR198,MIR29A,BNIP3L,NQO1,TSPO,CTNNBL1,BRMS1,PPP2R1A,PPARG,CAPN2,SFRP4,EIF2B5,TNF,ADIPOQ,IFIT2,MAP3K11,IL10,MIR101-1,MIR24-1,MSX1,PDCD1,TRAF2,PHB1,RPS3,PDIA3,STUB1,DFFA,CLU,HMGB1,CD40,KCNMA1,CDK5,PNMA2,BCL6,PNMA3,SAV1,S100A8,RPS7,NKX3-1,FBXW7,EMILIN1,ATF3,MIR98,RHOB,PLEKHF1,CCAR2,MIR23A,PYCARD,DUSP6,CCL2,MAP2K6,BMPR1B,NHERF1,CIDEB,ZNF622,SPHK2,PML,RBM5,MIR16-1,CRADD,CASP4,DCUN1D3,EIF2S1,MIR17,CYP1B1,GADD45A,ALDH1A3,SYCE3,CTLA4,CTSD |
| 4.666e-11 | -23.79 | mRNA Splicing | REACTOME pathways | R-HSA-72172 | 195 | 105 | 10285 | 3229 |
PPIH,CD2BP2,CASC3,HNRNPF,DHX15,DNAJC8,HNRNPC,SNRPN,DHX16,CWC15,MAGOH,PRPF31,SRSF4,LSM3,HNRNPD,POLR2B,HNRNPA0,PPWD1,ZCRB1,POLR2G,PRCC,GTF2F2,PQBP1,SNRPB,TRA2B,SF3B1,SNRPB2,DHX38,ELAVL2,SF3A1,SUGP1,SNRNP70,SMNDC1,TFIP11,SF3B4,POLR2C,CLP1,CPSF2,USP39,NCBP2,PAPOLA,SNRPD3,MAGOHB,DDX5,HNRNPH2,LSM6,LSM5,SNRPD2,SNRPE,TXNL4A,MIR7-1,SF3B5,MIR636,BUD31,SRSF1,HNRNPL,CDC40,GCFC2,LSM2,LSM4,PRPF19,CSTF2T,MIR1234,CPSF4,HNRNPA2B1,SNRPA1,SNRPD1,MIR939,DDX23,UPF3B,PRPF4,ZMAT5,HSPA8,SNRPG,POLR2D,WBP11,POLR2L,DDX42,POLR2F,LSM8,SRSF7,SRSF2,SRSF10,DDX46,ALYREF,EIF4A3,HNRNPK,DHX9,SNRPA,GTF2F1,CDC5L,POLR2I,SNRNP27,SLU7,HNRNPA1,CSTF3,RBM5,RBM22,CCAR1,SNRNP40,SNRNP48,RBM17,SF3B6,CPSF1,CTNNBL1 |
| 4.683e-11 | -23.78 | cellular response to oxygen-containing compound | biological process | GO:1901701 | 1047 | 404 | 18204 | 5365 |
PLAA,MIRLET7B,CRKL,MSN,NCOA5,AR,SOD1,GRIA1,MIR320A,XBP1,GNAI2,PID1,CD14,GSK3A,PRKCE,ADCY2,AKR1A1,RAMP3,ACACA,PHC1,JAK2,LRP6,TIRAP,MIR187,PCSK9,STAT1,TLR6,GRB10,SMAD4,SELENOS,DRD3,ITGA2,PPP3CA,MIR182,P2RY4,CEBPE,IL1B,ESD,TBC1D4,AKT1,AIFM1,SLC1A2,GSTP1,TXN,AGTRAP,NPR2,MAP1B,VDR,SLC1A1,TNFAIP3,GH1,CTNNB1,GPX1,GPT,MT3,CXCL11,UCP2,PDCD10,ROMO1,EP300,IGF1,NFKBIA,NSG1,PIK3R3,MSX2,CXCL3,CDC73,MIR96,MIR21,RGS10,GNRHR2,RWDD1,TNFRSF1B,PLCB1,PCK2,TLR9,JAK1,CD36,CD80,LDOC1,CIB2,ADCY3,SIN3A,PAX6,ELK1,SMYD3,EDNRA,WNT10B,AQP2,SLC1A3,GPR37L1,PPARA,JUN,AKT2,CD274,MPV17,CA2,LDLR,AHCYL1,CSK,CHRM4,IL6,EIF4E,TP53INP1,GNAO1,GNAQ,BGLAP,MMP9,CD86,MIR107,MIR223,YWHAG,SLC2A8,CXCL9,IL12B,MIR185,VPS54,P2RY11,NPTX1,STAT5A,CDK4,PPIF,XRCC5,CYP1B1,TICAM2,TRAF6,RARRES2,TLR2,DRD1,NFKB1,CHRM3,MIR16-1,GNA11,CCL2,FOS,NHERF1,NPPC,MAP2K6,PDE2A,HDAC6,TESC,FCGR2B,NFKBIL1,SELENOT,STAP1,TMIGD1,GNB1,CD40,PLSCR4,RAP1A,CRHBP,HNRNPD,WNT2,YES1,SLC23A2,CLTRN,STC1,SMAD3,FZD4,CAPN2,OPRK1,SHOC2,PIK3R2,PIK3R1,AMIGO1,SLC38A2,AKR1C1,TICAM1,NFE2L2,AKR1C2,FGF23,BACE1,PHB2,LEP,INSIG2,PIK3CG,MIR140,PDE4B,CSH1,MGARP,PRDX1,KCNJ11,GNG2,SRC,CALY,DAG1,P2RY12,PDCD4,MIR15A,MIR143,CAMP,GPR37,PIK3CA,ICAM1,BECN1,BRINP3,LITAF,RAB13,CPEB1,MIR20A,SOX9,CCR5,CTNNA1,MAP1LC3A,IRF8,SHC1,GNA14,CCS,HDAC5,MRC1,PRKCB,RAP1B,CRHR1,CRYGD,EIF4EBP2,CHRM1,OR51E2,ATP2B4,CAV2,KDM1A,FOLR2,STAT6,DDIT4,OSER1,ADRB2,SULT1A3,MTDH,HAND2,CXCL1,NFKBIB,PTPN22,GCLC,SPP1,GLRX2,PEX13,PCNA,AANAT,GJB2,TWNK,SESN3,IL18BP,KCNMB1,PLSCR3,DPEP1,IL1A,MAP2K3,CLDN1,IDE,CCDC186,FXN,ATP1A3,PSEN1,MIR146A,GFI1,HTRA2,BRCA1,SMAD2,MIR342,MYD88,CMA1,FKBP1B,MSTN,RUVBL2,STAMBPL1,EFNA5,MEF2C,CAV1,ACHE,USP8,HTR1A,GPBAR1,IRF3,CHRM5,CSF2,OPRM1,CDK5R1,ATP5F1A,LILRB1,KLF9,SOD3,CDK1,BCL10,HTR2A,INPP5K,CREB1,IGF1R,SFRP1,FBXO32,LY6H,PTGER2,SOCS2,PRDX3,DAPK1,KCNB1,MIR106B,RORB,DEFB124,GLRA1,SOS2,MIR200A,EPHA4,FOXC2,SLC29A1,PDCD1LG2,MIR17,GJA1,CFTR,NLRP3,CASTOR2,GUCY1B1,RAB31,TRA2B,PTGER1,CASP4,OGG1,RB1,CYP11B1,SLC22A12,VAMP2,CXCL10,FOLR1,HSP90B1,GLRA2,SPHK2,FBP1,MIR98,RHOB,PYCARD,HRAS,AGER,HMGB1,TOP2B,CDK5,PTK7,RDH11,RAB11B,MIR145,TRAF2,CX3CR1,RDH12,HRH3,RPS3,PPP1R1B,LY96,ADIPOQ,TNF,SHMT1,ACTB,CYP11B2,PTGFR,H2AZ1,ROCK2,IL10,RAF1,PPARG,SP1,CYP7A1,CXCL13,RPL23,PTGER4,CCNA2,MLC1,GAB1,KLHL22,TSPO,NQO1,CHMP5,IRAK4,SESN2,JUP,MIRLET7G,NCSTN,ESR2,EZH2,CHRNB2,CHRNA7,SLC6A4,NR4A2,EGR1,KLF4,TLR4,COMT,PRDX2,UGT1A1,PCGF2,TSHR,P2RY1,HSPA8,GHR,PTPN1,BRINP2,LARGE1,GPR173,CLEC7A,HPCA,CYGB,MIR34A,SOD2,CXCL8,MDM2,LPAR1,BRINP1,TP53,GNAI3 |
| 4.691e-11 | -23.78 | RBMX (RNA binding motif protein X-linked) | protein interactions | 27316 | 438 | 186 | 19454 | 5460 |
SNRPA1,SNRPD3,OSBP,HNRNPL,PAIP1,SRSF1,EED,YWHAB,MAGOH,WWP2,DDRGK1,CTNNB1,HNRNPF,TFG,HNRNPDL,PABPC1,RBM3,RPL31,TRIM11,EWSR1,PDHA1,PLS3,RHOBTB1,RND3,SNRNP40,MATR3,CMTR1,TACO1,SF3B4,FBXW11,CIRBP,MCAT,COP1,HNRNPC,HNRNPAB,SFN,APOBEC3B,MYC,SNRPB,ATG101,BTF3,STAU1,SRSF2,TRA2B,HNRNPA0,FXR2,UFL1,RPS28,NGRN,SNRPA,DDX5,RAMAC,EP300,HDAC5,HSPA8,SF3B1,CSNK1A1,NCOA5,KLC2,EIF4B,DUSP14,MTF1,SPPL3,FZR1,CAND1,CDC5L,MALSU1,CEBPG,SNRNP70,CHCHD1,ENY2,DPP4,CSNK2A1,HNRNPK,MEPCE,PSME1,DHX9,NFE2L2,NUPR1,GFM2,RPSA,METTL15,STAT5A,SRPK2,ZNF330,SF3B6,MACROH2A1,RC3H2,TLR9,NIF3L1,RBM7,UBE2H,ELAVL2,ST13,TWNK,HNRNPH2,GSTP1,HEXIM1,CDC42,DHX15,SRSF10,NTMT1,NABP1,PHB1,FOLR1,DDX23,RHOG,PPP3CA,RB1CC1,MRPS26,AHSA1,HNRNPD,MTRF1,PRPF19,TRA2A,HNRNPA1,TRIM37,G3BP1,SSRP1,SRSF4,HNRNPA2B1,ZC3H7A,HINT2,CHMP4C,EZH2,B3GNT2,ZNF263,RAF1,PPP2R1A,PRRC2A,USP5,JAK2,SNRPD1,SNRPD2,MYO6,RIT1,PMPCA,CUL3,MCM3,PRPF31,CMTM6,G3BP2,EMC9,FOXS1,APOBEC3C,RND2,PPP1CB,TOP1,CWC15,RCHY1,AIFM1,PRR3,CRBN,GRSF1,THRAP3,ILF2,MRPL11,APOBEC3D,EEF1A1,MAP1LC3B,SOCS3,NREP,MAGOHB,EIF4A3,CCNF,TRIM24,MSN,TXNIP,IVNS1ABP,PIP4K2C,PAIP2,PPP1CC,TUFM,NUCKS1,HMGB1,FBXW7,PDHB,GID8,SIRT7,PPIH,CLK1,METTL14,LMNA,MTRES1,ATG16L1,SF3A1 |
| 4.757e-11 | -23.77 | OPTN (optineurin) | protein interactions | 10133 | 418 | 179 | 19454 | 5460 |
ATP2B4,MTCH2,GNAI3,TFRC,RP9,GPD2,NFE2L2,RAP1B,EEF1B2,ILVBL,SURF6,TMED9,CAND1,GRM1,MIF,CSNK2A1,USP2,SNRNP70,SMCHD1,HNRNPH2,RAB9A,RPL27,UGDH,THUMPD1,POLD2,NLE1,TOMM20,LITAF,CFTR,ACACA,SDCBP,SGTA,UQCRC2,UBA3,TNFAIP3,SUB1,OAT,CISD1,EWSR1,TRIM21,PICK1,HNRNPDL,ROCK2,MIEF1,HEXA,DCUN1D5,SDC4,RAB1B,PAIP1,YWHAG,YWHAH,SYNJ2BP,WWP2,CDC23,YWHAB,HSPB1,AK2,IKBKB,HSPA8,AKAP1,ARRDC3,XRCC5,FOS,ARMCX2,UFL1,SERPINB6,QTRT2,MTMR6,PAK2,PALS2,SDC2,MAP2K1,SF3B4,TAX1BP1,FIS1,ZMPSTE24,S100A11,H2AZ2,FAF1,SFXN1,VWF,MRPL22,TOM1,HSPE1,MAP1LC3B,DDX39A,GGCT,TBK1,RAD23B,HRAS,RPL12,TOMM70,GLO1,SLC25A46,OSBPL8,EIF5A2,SQSTM1,MAVS,SOD1,PPM1G,BRIX1,GABARAP,CDK7,FTH1,GABARAPL2,ATG16L1,RPLP0,RARS1,RPL26L1,EPHX1,SHOC2,ZMYM6,CDK1,OPTN,TUBA1B,UQCRQ,UBB,GNAI2,RAB14,PNP,LDHA,SNX3,ATP5F1A,NDUFB10,RETSAT,XPOT,SMAD2,HSPD1,RPS27A,MRPS17,TNF,KCTD17,GFPT1,GABARAPL1,RBM12,ARFGAP1,STX12,POLR2C,EXOSC3,MAP1LC3A,DNM2,PSMB4,CACYBP,SLMAP,RAB11B,MPP1,ATG9A,MARCHF5,RB1CC1,WDR12,BIRC2,HADHA,NUP50,RNF11,ZDHHC17,CDKN1A,LNX2,MTX2,TBC1D17,MYL6,ARMCX3,RMDN3,SNRPD2,UBE2S,RAN,CHCHD3,RPL19,USP5,JAK2,EIF4A2,LGALS3,DYNLL1,TOMM40,RAB11A,CFAP20,MYO6,YWHAZ,WDR20,DCAF4 |
| 5.024e-11 | -23.71 | orf3 (NS3 protein) | protein interactions | 14254595 | 540 | 221 | 19454 | 5460 |
AGK,ATXN10,RPL7,OCRL,PSMB5,PHB1,PSMB4,DNM2,THOC2,AHSA1,HAX1,SKIC8,EIF3D,MMUT,STOML2,PDIA3,RFC2,GTF3C3,MCM6,PSMD12,G3BP1,NEK9,NME1,GDI2,ERLIN2,GFPT1,NUP153,JUN,CA8,FEN1,NAA15,HSDL2,USP5,MAT2B,MAD2L1,TAB1,UMPS,SEC61B,RAN,CYB5R3,CPSF1,ILK,HSP90AA1,MYO6,SAMHD1,PMPCA,PYCR1,CUL3,UNC45A,PSMC1,PYGB,PSMA3,HADHA,NUP50,ATP5MK,SLC25A3,LARP4B,ADNP,USP39,PSMB7,VAPB,TIMM13,IDH3B,PGRMC1,MAPRE2,HACD3,PTPN1,AIFM1,DNAJC7,LRRC40,CALR,GRSF1,EIF3E,MSH6,PTGES3,PRDX4,RPS13,CTNND1,VTA1,FARSA,HUWE1,SFXN1,NSDHL,RAD23B,DHRS7B,APEH,ILF2,CD2BP2,YTHDF2,CCDC47,RPL22,RPS20,GNPDA1,PRKRA,GANAB,EIF4A3,ENO1,VAMP3,CDC73,AP2A1,CA2,USP14,PYCR2,TMEM209,TMUB1,GTF2I,PPIH,HMCES,PRIM2,INPPL1,WTAP,RARS1,EPHX1,PIP5K1A,PSMC4,RAB1B,RPS10,WDR82,HDHD5,FUBP3,DRG1,YWHAB,HSPB1,CTNNB1,XPO1,PPIB,RIOX2,RAB5C,RPS4X,PSMA1,RTCB,EWSR1,CDK5,RPAP3,PDHA1,UCK2,NUP37,NCSTN,CBX5,PSMB6,FBXO22,TAGLN2,MATR3,SMU1,VDAC2,MCAT,POLR1B,OSGEP,RPS26,PSMD14,CKB,UFD1,PSMD1,TBCE,OXCT1,SERPINB6,PHB2,RAB5A,SF3B1,XRCC5,RPS28,RFC4,AKR1A1,UBAC2,PSMB3,LAP3,TMPO,ESD,CNPY4,AKR1B1,DSTN,UBE2N,SDHB,SSBP1,ACSL4,RPL10A,RPS2,KPNA1,RPL24,SMCHD1,DNAJB2,KARS1,RDH11,TMEM33,NUP107,PSMA5,ABCE1,SLC25A11,GNAI3,PSMC3,TBC1D4,CAPZA2,CBX3,HADH,ACTR1A,UBL4A,SUCLG2,BUB3,EIF2S2,SRP54,PSMA6,PSPC1,SORD,OAT,IGF2BP1,GSTK1,RPL7A,PSMB2,SLC25A1,HSPA5,GFM1,HNRNPH2,NBN,RPL27,UGDH,HECTD1,ACACA,UBE2M,IDH2,PPP1R8,AKR7A2 |
| 5.140e-11 | -23.69 | COPS6 (COP9 signalosome subunit 6) | protein interactions | 10980 | 387 | 168 | 19454 | 5460 |
ANXA7,CDKN1A,DET1,TOR1AIP2,FBXO42,SKP1,UCHL3,DDX5,EP300,SAT1,NMRAL1,APPBP2,HSPA8,COX17,FBXW4,FOS,COP1,HSP90AA1,PSMD14,DCAF4,RFC5,SAMHD1,CUL2,CUL3,SFN,HNRNPAB,SYCE3,COPS7A,ERH,ACTB,FBXO22,DYNLL1,TUBB,ZMAT2,SNRPD1,FAU,FBXL14,CPSF1,RPL18,RHOBTB1,SERPINA5,KLHL12,RPS11,CRELD1,TUBB4B,IRF8,TULP3,EEF2,JUN,CKS1B,PAEP,COPS4,HNRNPDL,TFG,RPS4X,S100A10,KRAS,HNRNPF,COA1,UBE3A,FBXO11,EWSR1,CDKN2C,PABPC1,HNRNPA2B1,SLC25A5,RPL31,RPL23,STAMBPL1,DCAF11,PDZK1IP1,LYZ,CDKN1B,HNRNPD,FEM1B,NT5C2,SHC3,RPL6,DCAF4L2,PRDX1,HSP90AB1,KCTD10,COPS7B,STX5,RPLP2,COPS2,RPLP1,FBXO32,WDR6,RPL8,SIN3A,UBE2M,HNRNPH3,HSP90B1,RPA2,CCNA2,RPS14,HSPA5,FBXW7,RPL4,WDR3,MAVS,CCDC106,HNRNPH2,PHYHIP,MAPKAPK3,BAP1,RPA3,UBE2H,STK11,DTL,NCKIPSD,DCAF16,HMOX2,FBXO7,ATP5F1A,FBXO44,NUDT1,TXN,KCTD9,PTEN,RPS20,SYT2,PRKRA,POP7,PAFAH1B3,DCAF12L2,RPL15,MAP1LC3B,CDK4,TP53,SERPINB9,SNRPG,EIF3E,RIGI,MNAT1,SMN1,APBB3,HUWE1,NEDD8,KLHL15,CLPB,RAB27A,KLHL24,ORAI2,RPS2,SNRNP70,RPL24,SLC2A1,CRBN,ELOC,GAPDH,KLHL22,COPS5,ROGDI,ZNF24,COX5A,AP5S1,KLHL9,NFKB1,LRRC14,SCG2,PRNP,MIF,DCUN1D1,KCTD3,EHBP1,SYNCRIP |
| 5.152e-11 | -23.69 | DUX4 (double homeobox 4) | protein interactions | 100288687 | 214 | 105 | 19454 | 5460 |
CCT2,RIT1,RPS5,CREBBP,RPL35,TUBB,PRDX2,DES,RPL19,RPL10,PSMB6,RAN,ARF1,VDAC2,RPS9,MYL6,SLC25A3,ACTL6A,RPL27A,XRCC5,EP300,DDX5,SF3B1,RPL23,RPL6,PRDX1,CTNNB1,TCP1,RPL7,SPTAN1,RPS10,RAB11B,CCT7,RPL8,RPL9,BZW2,RPN1,RPL18,PNMA5,RANBP1,EEF2,RPS7,PPP2R1A,VDAC1,HNRNPF,RBBP7,RPS4X,PABPC1,CCT8,RBM3,RPL31,HSPD1,SLC25A5,RPS24,PDIA6,EIF3G,IGF2BP1,AP2A1,RPL7A,NONO,RPS17,LDHA,RPL22,IDE,ENO1,PSMA6,RPS3,RPS20,HSP90B1,LMNA,GSTP1,RPS14,SPTBN1,EIF3J,RPL4,HMGB1,RPS15,MARS1,RPL27,RPL10A,RPS2,KARS1,TPM3,GAPDH,CAND1,RPS16,RPL12,SYNCRIP,CBX3,CAPN2,ILF2,RPSA,CCT5,RPL15,ACTR1A,CSE1L,HNRNPK,RPL17,SNRPG,RPS13,PSME1,RAB1A,DHX9,RPL3,RPL23A |
| 5.175e-11 | -23.68 | RPLP0 (ribosomal protein lateral stalk subunit P0) | protein interactions | 6175 | 614 | 246 | 19454 | 5460 |
ACOX1,PSPC1,RPS3,MACROH2A1,RPL10L,SRPK2,RSL24D1,RPF2,RPL7A,RPS17,RC3H2,UBE2H,RRP7A,RPL27,BAP1,RNF113A,RPS15,MARS1,CDC42,NEK2,CFTR,RPA2,DYRK2,HEXIM1,ZNF770,SYNCRIP,RPL32,CD4,DNAJC1,RPS16,CAND1,FZR1,DKC1,RBM42,SURF6,ENY2,COPS5,CD81,CSNK2A1,API5,GAPDH,CENPL,TUBG1,RPL24,SNRNP70,CDK12,RPS2,RPL10A,RPL3,DHX9,NEDD8,IMP4,MEPCE,RPL17,IMP3,UBL4A,TP53,IPO8,RPSA,H2AX,TFCP2,RBM34,DNAJC2,RNF8,ZCCHC7,ESR2,RPL10,MYC,BTF3,FTSJ3,RPS26,ICAM1,H1-1,NSA2,HSPA8,SF3B1,HDAC5,YAF2,RAB5A,UFL1,FXR2,STAU1,MTF1,RPL27A,PPT1,PIH1D1,SRSF1,EIF2S1,HNRNPL,RPS10,LYAR,HSP90AB1,IFI16,DDX50,RPL6,WWP2,CTNNB1,NGDN,DDRGK1,NCK1,AGR2,DRG1,RPL31,PABPC1,EWSR1,KRAS,NUP42,RPS4X,RPL28,MAGEB10,DNAJC25,RPS7,GLE1,RPS23,RPL18,OPTN,CCNF,PELP1,EIF2AK2,METAP2,PRKRA,RPS20,PTEN,RPS12,NDN,RPL13A,VIRMA,RPL22,RPL26,DNAJC8,CDC73,DNAJC19,CASC3,INPPL1,RPA3,SIRT7,IDH3A,KIN,MTDH,NPM3,EIF5B,RPL4,HMGB1,FBXW7,AATF,UTP23,BRIX1,RPS14,EEF1E1,TPT1,CDK7,GRM2,METTL14,RPL26L1,RARS1,ZNF574,MACROH2A2,HAUS2,RPL12,SMAD3,SRP14,KRR1,RPL35A,DCUN1D1,PRNP,AKAP17A,CDK9,GRSF1,EMC4,SPATS2L,HDAC6,MPHOSPH10,FAF1,NKRF,RPL23A,PAK1IP1,HUWE1,FARSA,VRK1,RPS13,FBP1,EEF1A1,TAF1D,RPL15,EXOSC8,LLPH,ILF2,SRP72,ZNF22,RPL37A,RPS9,SEC61B,RPF1,RPL7L1,RBBP4,RPL35,ACTB,RPL19,CUL3,CUL2,NOP16,ZNF668,FYTTD1,HSP90AA1,RPS5,RIT1,HTR1A,NMRAL1,PAFAH1B2,NOP53,G3BP2,H1-5,EMC9,RPL8,FOLR1,RPL9,PHB1,MYEF2,RPLP1,HP1BP3,RPLP2,RPL7,NDUFS8,ATG7,HNRNPA1,HNRNPD,RSBN1L,RPL23,DICER1,HNRNPA2B1,RPS24,MRPS11,G3BP1,GNL1,TRIM37,RPS27A,B3GNT2,OTUD6B,MAK16,RPL29,ACTN4,ZNF397,EZH2,CHMP4C,NGB,RPS11 |
| 5.225e-11 | -23.67 | COPB2 (COPI coat complex subunit beta 2) | protein interactions | 9276 | 342 | 152 | 19454 | 5460 |
XPO1,HNRNPA1,DDRGK1,AGR2,MYEF2,CYB5A,HNRNPL,SUMO2,SLMAP,ERLIN1,TMEM237,CEP19,CETN2,E2F4,ISG15,TUBB4B,CHMP4C,DHRS3,RNF126,TMT1A,HNRNPA2B1,ACTR1B,G3BP1,KRAS,ATP5F1D,TRIM37,MCM6,HNRNPDL,SACM1L,RAD21,RAB18,OST4,MYC,KDSR,TMED5,CUL3,HNRNPC,MCM4,FAS,MCM8,BRCA1,MYO6,ATG3,SCFD1,NTRK3,POLR1B,SERPINH1,ILK,RIT1,LMBR1L,NFKBIA,MCPH1,PRDX2,MATR3,REEP4,TUBB,ESR2,USP5,ATP6AP2,SEC62,EDEM3,VAPB,PIH1D1,ARCN1,WBP2,HDAC5,PMAIP1,EP300,UFL1,STAU1,RER1,NFKB1,EI24,FAM20C,DHRS7,EMC4,GOLPH3L,KCNJ10,ESYT1,OSBPL8,STYK1,CD274,ITGA6,HSD17B11,TMED9,FZR1,ARF6,SELENOI,ILVBL,LMAN1,STX6,TOMM70,CDK9,ZBTB2,CDC5L,MRPL24,TBK1,CCDC47,KBTBD4,INSIG2,TP53,PHF23,DDX39A,LBR,SURF4,MINDY3,CIBAR1,NSDHL,SEPTIN7,EMC2,HUWE1,TGFBR2,TMEM33,SMIM11,ARF4,MEPCE,PRDX4,RDH11,DEPDC1B,USP14,IFNAR1,NONO,ENDOD1,ATP1A1,UBE2H,CCNF,FAM210A,ATL1,GANAB,COPZ2,NDN,COPE,PRKCE,SMURF1,VIRMA,CFTR,RPA2,SSR1,FGFR1,ZNF326,HEXIM1,UBE2M,PPM1G,RPA3,SEPTIN6,BAP1,TMX2,TEX264,APMAP,SIRT7,RTN4,RGS2 |
| 5.332e-11 | -23.65 | S (surface glycoprotein) | protein interactions | 43740568 | 728 | 284 | 19454 | 5460 |
TP53,RPSA,TMEM165,NHERF1,ARPC3,CD209,CBX3,TFRC,SLC25A24,FURIN,SLC25A11,IDH1,SLC16A1,ERO1A,CSE1L,TMEM33,H3C1,SLC6A8,COX5A,DPP4,TPM3,GAPDH,CAMP,COX4I1,SYNCRIP,RAP1B,RPS27L,CPNE1,RPS16,CD99L2,LMAN1,ILVBL,DKC1,RBM42,CDC42,WWP1,IDH2,SAMM50,SDCBP,CD46,CYC1,AVPR1B,IRF3,BANF1,SEPTIN6,APMAP,LCP1,DLAT,PRDX6,GFM1,ZBED3,OIP5,HDAC3,CLU,HSPA5,GRPEL1,SLC25A1,GORASP2,RPS17,CFL1,F9,SORD,SNX5,ALKBH5,CALU,IGF2BP1,ATP1A1,OAT,NECTIN2,ALG2,CDIPT,SF3B6,CCSER2,TXNDC12,CTSB,DAPK3,SMURF1,ETFB,TUBA1A,PDHA1,NUDT19,PLS3,HGS,ABCF1,PDIA6,MYO1B,RUVBL2,EFNB1,VDAC1,CHCHD2,POLDIP3,RAB18,RAB5C,WWP2,XPO1,YWHAG,FKBP4,SFTPD,AK2,HSPB1,DRG1,DENND6B,SDC4,FBXO31,PTK7,S100A8,CORO1C,TRIR,EIF2S1,CDK17,RPS10,RAB1B,LDAH,YIPF5,CTBP1,SDC2,EIF4B,SPECC1L,TMEM106B,XRCC5,DDX39B,MIA2,LCN1,SLC31A1,SRSF2,LYPLA2,SAP18,ITGAV,LDHB,TMEM38B,COX6B1,APOBEC3B,HMGCS1,BTF3,CKB,MDH1,DLST,ZNHIT6,VDAC2,MBL2,ATP5F1B,STAT2,STAT1,CBX5,CMPK1,HINT3,DDX39A,POLR2G,C1QC,RAB1A,TLR4,SNAP23,ERLEC1,LSM4,HUWE1,ARF4,VWF,CALR,MPG,NME2,SLC2A1,POR,DNAJC7,PTPN1,SRPRA,HACD3,PWP2,LDLR,CDCA3,SEC23A,NELL2,TCEAL8,PRNP,ALCAM,MSMO1,CAV1,ATP5PD,SEC22B,SNRPN,ARHGAP1,MYL12B,FUT8,RABL3,UQCRC1,STOM,HSP90B1,LMNA,PDCL,HNRNPH3,TMOD1,CCSAP,SOD1,SPCS2,MAVS,RTN4,ARPC2,TCEA1,ITGA2,YKT6,GTF2I,PDHB,USP14,TUFM,HMOX2,LGALS8,SDF2L1,CHORDC1,EPHA2,NAPA,CCHCR1,NRP1,F10,EIF4A3,ALB,MSN,RPL13A,TMOD3,F11R,MGST3,COPE,DEK,TECR,MARCKSL1,HSDL2,TULP3,ERLIN2,ACTN4,GDI2,MOXD1,RPN1,ITGB5,ERP29,BAG2,SELENOP,JAK1,PCNA,ENKD1,GOLGA7,RAD21,STOML2,PDIA3,HNRNPA1,HBA1,CDK5RAP3,RHOG,RPL23,TMEM30A,AHSA1,LYZ,SNX2,NUP35,PPIA,NOTCH2,PGRMC1,AGTRAP,NDE1,RAB6A,ATAT1,PRDX3,PCLAF,VAPB,MYL6,SLC25A3,ANXA7,ARCN1,RTKN,YTHDF1,CNTN1,F2,RAB11A,ACO2,MCM4,MCM3,MRPL16,CTSK,LMNB1,HTRA2,CYB5R3,DPEP1,GNG12,AP2M1,LGALS3,STARD7,MB21D2 |
| 5.351e-11 | -23.65 | TBRG4 (transforming growth factor beta regulator 4) | protein interactions | 9238 | 390 | 169 | 19454 | 5460 |
FIS1,MRPS25,AK3,MRPL16,HNRNPAB,PYCR1,GPR17,ESR2,NDUFAF4,APEX1,FRRS1L,ATP5F1B,MRPL23,MRPL13,RETREG3,TRMT11,DLST,TACO1,LMBR1L,CD79B,NDUFA5,NCOA5,MRPS18A,ATP5PO,NDUFAF3,MRPL12,PRDX3,AGTRAP,FAM234A,MRPS7,NT5C3A,STAU1,PHB2,NDUFS2,PTN,NPTN,HADHA,ATP5IF1,NGRN,CXCR4,MRPS26,MRPL18,DDRGK1,NDUFV2,MRPL9,P2RY10,STOML2,FAM174A,MRPS35,CLPX,PGAP3,WIF1,SRSF10,NDUFS8,RAMP3,PNPLA8,HNRNPL,GATD3,FAHD1,CYB5B,RPS23,OTULIN,NDUFA12,NDUFS6,PDHA1,CA14,ETFB,HSDL2,HNRNPDL,IMMP2L,MRPS17,SEMA4C,ATP5F1D,KGD4,ETFA,COX8A,MRPS11,HINT2,CD83,NDUFA4,HSPD1,OAT,BICD2,MRPS16,PYCR2,NDUFAF2,MRPS21,ACAT1,MRPS28,SYNGR1,EIF2AK2,MRPL53,TFIP11,LMNA,RPA2,MRPS34,QRSL1,MRPL10,HCST,NDUFAB1,TIMMDC1,WDR83,MRPL20,POLDIP2,MRPL41,MRPL40,NME4,MRPL17,PDHB,DLAT,GFM1,TWNK,VIPR1,AMACR,PML,RPA3,SLC39A9,SHC1,SMAD4,LYPLAL1,GPRASP2,LAMP3,ATP5MG,COX5A,MOV10,GRSF1,MRPS23,MRPL24,ATP5PD,DBT,MALSU1,DERL2,PRNP,MRPL50,FA2H,MGME1,CDR2L,COX4I1,MRPS9,CD274,SSBP1,SDHB,MRPL49,MRPL51,NDUFS3,METTL15,BCS1L,PPIF,HADH,MRPL47,NDUFA2,RAP1A,COMTD1,ATP5PB,CCDC47,H2AC6,MRPS18C,MRPL22,FASTKD5,HSPE1,CD80,PDE12,TNFSF8,MRPS33,HSD17B10,THG1L,MRPS18B,ATP5PF,MRPL52 |
| 5.412e-11 | -23.64 | RBM14 (RNA binding motif protein 14) | protein interactions | 10432 | 514 | 212 | 19454 | 5460 |
MIR1-2,SF3A1,ATG16L1,HNRNPH3,LMNA,METTL14,MIRLET7I,MIR34C,RPA3,MIR205,PIAS1,SS18,FBXW7,MIR7-3,RUNX1,FBXO7,USP14,PPP1CC,NONO,AR,SMAD2,NRP1,MIR145,TRIM27,RPS20,UBE2I,CCNF,MIR16-1,EIF4A3,RAB14,MAP1LC3B,MIR200C,MIR15A,ILF2,CASK,MIR17,MIR20A,NKRF,OLA1,THRAP3,TRIM63,HDAC6,MOV10,MIR34A,MIR25,MIR106B,SMAD3,RCHY1,CDK9,TOP1,WDR77,MFAP1,MED23,BIRC2,MIR106A,SKP1,SMARCE1,MIR98,CUL3,RAB11A,CUL2,MIR363,RPS5,DCAF4,BRCA1,YWHAZ,SNRPD2,SNRPD1,CPSF1,MIRLET7D,TNPO3,RAF1,NAA15,B3GNT2,TPBG,POLR2C,EZH2,RPN1,CHMP4C,HNRNPA2B1,SSRP1,HNRNPA1,PRPF19,RB1CC1,MED4,MIR1-1,DROSHA,HP1BP3,MIR141,CBFB,MIR7-2,PHB1,SRSF10,NUP35,CCAR2,CFTR,MIR34B,HEXIM1,DYRK2,MIR21,MIR7-1,LEMD3,RPA2,WWP1,ZNF326,HNRNPH2,RNF113A,RAB9A,BAP1,MIR10B,NLE1,MIR29A,MIR107,HSPA5,SMARCA5,SUB1,IGF2BP1,UBE2H,SPOP,CRLF3,RC3H2,PSPC1,CSTF3,PPP1R10,TP53,NUPR1,FURIN,IK,DISC1,CLPB,DHX9,MIR9-3,MIR200A,MIRLET7C,MIR16-2,HNRNPK,GPRASP2,SSBP4,COPS5,USP15,SMAD4,ARL4D,SYNCRIP,SDHB,MIR429,TMPO,CAND1,FZR1,MIRLET7G,MIF,BET1,NCOA5,TRMT112,CTBP1,SF3B1,HSPA8,HDAC5,EP300,DDX5,XRCC5,SAP18,UFL1,HNRNPA0,FXR2,TRA2B,STAU1,BTF3,CPSF2,MYC,SFN,HNRNPC,RPS26,CDKL2,FTSJ3,MIRLET7B,MATR3,SNRNP40,MIR222,SOX2,RPS7,TOP3B,MTA2,HDAC11,MIR206,TOP2B,MIR9-2,HNRNPDL,MIR155,MIR29C,YWHAH,YWHAG,CTNNB1,DDRGK1,IFI16,WWP2,MIR143,MIR221,YWHAB,MIR140,AGR2,MIR31,WDR82,EED,MIR214,RAB35,HOMER3,RBM5,SRSF1,PEG10,HNRNPL,MIR9-1,SNRPA1 |
| 5.577e-11 | -23.61 | RPL22 (ribosomal protein L22) | protein interactions | 6146 | 376 | 164 | 19454 | 5460 |
CD4,SRP14,RPL12,RPL32,RBM42,MDM2,SURF6,FZR1,RPS16,CAND1,RPL35A,RPS27L,COPS5,CD81,CSNK2A1,HDAC6,ENY2,EMC4,RPS2,RPL10A,TUBG1,RPL24,SNRNP70,RPL23A,ABCE1,MRFAP1,RPL3,MAP1B,RPS13,MEPCE,RPL17,HUWE1,CSE1L,VRK1,THAP1,RPL15,FBP1,UBL4A,RPSA,SRP72,RNF8,DNAJC2,PRKRA,RPS12,PTEN,RPS20,PSPC1,RPS3,CCNF,METAP2,SMURF1,RPL22,SRPK2,VIRMA,RPL10L,RPL13A,RPL26,RPS17,USP14,PPP1CC,CIAO1,RPL7A,CDC73,UBE2H,ATP1B3,EIF3G,RC3H2,RNF113A,SNAPC1,RPL27,BAP1,RPA3,PIAS1,BRIX1,AATF,RPS15,NUCKS1,FBXW7,HMGB1,RPL4,GTF3C4,CDC42,FBXL19,CDK7,CFTR,ATG16L1,RPS14,DDIT4L,TPT1,HEXIM1,RPL26L1,RPLP0,RPA2,SDCBP,FGFR1,ZCCHC17,METTL14,EED,RPLP2,FOLR1,RPL9,RPL8,PHB1,DHX15,RPS10,RPL7,ATG7,DDRGK1,ZCCHC10,WWP2,RPL6,RSBN1L,POU5F1,AHSA1,DRG1,RPL23,AGR2,TMEM147,RPS24,UBE3A,RPL31,RPS27A,RPS4X,RAD21,G3BP1,KRAS,TNF,TRIM37,RPL29,RPS7,B3GNT2,TOP3B,ARFGAP1,RPS11,RPL18,RPS23,EZH2,RPL37A,AP2M1,RPS9,SEC61B,RPL10,RPL19,RPL35,BTF3,MYC,CUL2,STAC3,CUL3,RPS5,ICAM1,RPS26,FTSJ3,G3BP2,UFL1,NSFL1C,STAU1,RPL27A,PAFAH1B1,HEXB,EIF4B,PIH1D1,PPT1,EMC9 |
| 5.609e-11 | -23.60 | STX3 (syntaxin 3) | protein interactions | 6809 | 140 | 76 | 19454 | 5460 |
STX7,YKT6,GOSR1,NMRAL1,RAB5A,TMEM185A,TMX2,RHOU,JAGN1,LMNA,VAPB,PTP4A2,CPLX2,MANBAL,USE1,YIPF5,CDC42,STXBP1,TOMM22,BET1,MGST3,REEP4,RMDN3,STX10,VAMP3,ELOVL4,MFSD14B,SCFD1,NAPA,CHORDC1,STXBP6,RHOB,CYB561,SAMHD1,DNAJC5,CSK,SCN3B,VAMP5,RAB11A,VAMP8,MSH6,G3BP1,KRAS,RAB3B,STX18,SNAP23,STX8,RINT1,CYB5B,TMEM14B,VAMP2,ZNF526,SNAP29,TBK1,PPIA,SLMAP,VAMP7,NCBP2,STX6,MSMO1,CAV1,HNRNPL,SNAP25,NRSN1,STX5,THOC2,FBXO31,HRAS,MYEF2,ZDHHC15,STX1A,RHOG,SYT4,MAP3K14,SYNJ2BP,KRBOX4 |
| 5.734e-11 | -23.58 | GORASP2 (golgi reassembly stacking protein 2) | protein interactions | 26003 | 362 | 159 | 19454 | 5460 |
UGDH,DERL1,RAB9A,MIEN1,HSPA5,DUSP18,SEC22B,CDC42,SLC35E1,ST7,GNG7,SSR1,FGFR1,CHMP1A,RARS1,DCTD,CARHSP1,GSTP1,GTF2A1,KCTD9,TECR,TRAF1,ZMYND19,RAB2A,RGL2,AAMDC,TIA1,PCBD1,NONO,NRP1,NAPA,REEP6,RAB1A,TMED1,SEPTIN7,NTRK2,RAB3B,RPIA,ARF4,DUSP21,GALNT2,EEF1A1,EMILIN3,MAP1LC3B,UBIAD1,TMEM165,SH3GLB1,FURIN,PDE9A,HRAS,HSD17B11,DECR2,RAC2,TMED9,ARF6,MIF,EPHB6,LMAN1,STX6,CAV1,DPP4,LAMP3,STYK1,ATP2C1,RAB5A,AKAP1,PSMA3,RER1,TMED3,PXMP2,STX7,ATP6V1G1,NUP62,BET1,UBL3,PGRMC1,BEND5,SHMT1,RND2,OTULINL,PRDX3,SEC62,SEC22A,CRYAB,GRIK1,GTF2IRD1,NCOA5,ZER1,TRAPPC6A,TRMT6,LMBR1L,CCDC90B,ATXN1L,RMDN3,SEC61B,TSN,PSMD6,PRRC2A,ESR2,CUL3,TMED4,RAB11A,CDKN2D,BAG3,SLC30A5,LAMTOR1,SCFD1,NTRK3,NUDT5,SCYL2,ALKBH4,TMT1A,RUVBL2,CDK5,EWSR1,ARL5B,EPHA4,KRAS,ZBED1,ZBTB14,XPNPEP1,MATN4,TMED7,PRPS1,FLOT1,SAR1B,RAB18,TOP3B,E2F4,PNMA5,TRAF2,ERLIN2,STIM1,RPN1,NME1,PTRH2,SCAND1,RAB4A,SMARCB1,RAB35,PRCC,GJA1,DIPK2A,STX5,ODC1,RAB1B,ECHDC1,RHOH,CGGBP1,HSBP1,LAMP2,ATG9A,RAB5C,IFT25,PPIB,FIG4,XPO1,RHOG,CDC23 |
| 5.734e-11 | -23.58 | SNRPD2 (small nuclear ribonucleoprotein D2 polypeptide) | protein interactions | 6633 | 362 | 159 | 19454 | 5460 |
DDX42,GEMIN7,ILF2,UBL4A,CD2BP2,THRAP3,TSSC4,SNRNP48,LSM4,SMN1,SNRPG,RIGI,VTA1,MEPCE,PSME1,SNIP1,METTL18,ECD,SNRNP70,MAP4,LSM3,RBM17,COPS5,TOP1,PRNP,CAND1,DCUN1D1,FZR1,CWC15,CDC5L,ZBTB2,TMPO,CDK9,RBM42,RCHY1,ALYREF,PTPN1,SRP14,METTL14,LSM2,RPA2,LMNA,LUC7L3,HEXIM1,UBE2M,TFIP11,SNRPN,SF3A1,TXNL4A,CFTR,HSPA5,PRPF4,RPA3,DDX46,BAP1,NCDN,PPIH,GEMIN8,RC3H2,LSM6,CRLF3,UBE2H,MAPRE1,ZBTB38,NAPA,SUGP1,PPP1CC,DNAJC8,CEP70,H2BC9,CHMP5,ADRM1,SMURF1,EIF4A3,SF3B6,OPTN,CINP,CCNF,PSMC5,SMNDC1,NGB,EZH2,SART3,SNRPE,SF3B5,E2F4,RAF1,SOX2,PPP2R1A,NCSTN,HNRNPF,RBBP7,KRAS,SSRP1,HSPD1,CMTR2,SRSF7,RUVBL2,SETD4,EWSR1,AGR2,SKIC8,DDX23,MAGOH,WWP2,ZCCHC10,PRPF19,PSMD3,CTNNB1,DDRGK1,YWHAH,HNRNPA1,LSM5,DYNC1I2,SNRPA1,SNRPD3,DHX15,OS9,PHB1,SRSF1,PSMB5,IFIT2,EED,USP39,PIH1D1,PAFAH1B1,WDR77,ELK4,STAU1,EEF1G,UFL1,TRA2B,SRSF2,COIL,SAP18,XRCC5,DDX39B,SNRPA,DDX5,HSPA8,SF3B1,ZCRB1,RIT1,CUL3,CUL2,MYC,SNRPB,TTC33,BTF3,PRPF31,LGALS3,SNRNP40,MATR3,ESR2,SNRPB2,SF3B4,PRMT5,SNRPD2,SNRPD1 |
| 5.745e-11 | -23.58 | ER-Phagosome pathway | REACTOME pathways | R-HSA-1236974 | 85 | 56 | 10285 | 3229 |
PSMD10,CD36,PSME1,TLR1,VAMP3,PSMD7,PSMD14,VAMP8,UBA52,TLR4,UBB,PSMB7,SNAP23,PSMD3,PSMB1,PSMB5,PSMA3,PSMC4,TLR6,PSMA4,PSMA5,PSMB10,LY96,B2M,PSMC5,PSMB11,PSMB6,PSMA2,SEC61A2,SEC61B,PSMB3,PSME2,SEC61G,TLR2,IKBKB,PSMB4,PSMD6,SEM1,CD14,PSMB9,MYD88,SEC22B,PSMC3,PSMA1,RPS27A,PSMD4,TIRAP,CALR,PSMC1,SEC61A1,PSMD12,PDIA3,TAPBP,PSMD1,PSMB2,PSMA6 |
| 5.809e-11 | -23.57 | TRIM25 (tripartite motif containing 25) | protein interactions | 7706 | 2387 | 805 | 19454 | 5460 |
NOP53,AZGP1,PYGB,SERTAD2,PSMA3,LARP4B,LRRTM3,USP39,PSMB7,TOR1AIP2,PRDX2,IP6K1,CLIC4,USP5,ZMAT2,FAM219A,SETD7,BAX,HSP90AA1,NIBAN2,ACO2,PRPF31,SEMA4C,DHX16,SACM1L,TMED7,HNRNPA2B1,SYPL1,HSPD1,UCP2,PCNA,MKLN1,GDI2,LYPLA1,BUD23,RAF1,PPP2R1A,PPIA,RPL8,RPLP2,SLC20A1,ST3GAL4,DICER1,PDAP1,MED4,VPS4A,BABAM1,PPP2R5A,IFIH1,BRIX1,RPA3,RTN4,PICALM,DCTN4,HNRNPH3,RARS1,DDAH1,ARHGAP1,ADIPOR1,MREG,SLC35E1,TENT4A,COPE,FERMT2,METAP2,CCNF,RPS12,SH3BP5L,HERC4,STK38L,RPL26,FBXO7,B4GALT7,VRK1,ANAPC11,RIGI,APBB3,TCOF1,RPL23A,TGIF2,RNF121,CMPK1,UBE2V1,BLOC1S3,RPL35A,RPL12,SMAD3,ERCC3,GRSF1,ATP1B1,CDC42SE2,PID1,HM13,SRSF2,SLC31A1,CERS6,ITGAV,BMPR1A,DDX39B,DDX5,DR1,MAP2K1,GTF2IRD1,TAGLN2,MATR3,IRF2,ZMYM2,MRPS25,SLCO3A1,KIAA1191,MDH1,FIS1,COP1,OAZ1,RPS26,PSMA4,SFN,HNRNPAB,CREBBP,ST3GAL2,SNRPB,STX16,BTF3,XPNPEP1,SLC20A2,IMPA2,TFG,RPS4X,ABCF1,LTO1,BCL9,MOB3C,CLDN12,RPS7,FOXJ3,SNRPD3,SUMO2,MITF,HNRNPL,COCH,HSP90AB1,TRMT61A,KCNG3,PRCC,SIN3A,RAB31,MIR221,CBL,DDX1,PTDSS1,CDC26,WWP2,DDRGK1,CTNNB1,STK38,RPS15,GRPEL1,PHACTR1,PML,IRF3,RPL27,GRAMD2B,DERL1,DLAT,PGK1,LSM12,RNF34,POLR1D,TRAF7,BICD2,ATP1B3,ALKBH5,UBE2H,AP3S2,RPL7A,NPTX1,RAB2A,DNAJC5,TGFBR2,CHMP1B,RPL17,TNKS2,GNAI3,CERK,NUPR1,KIF1C,ATP5PB,MVD,CPNE1,ALYREF,UBE2G2,UBE2N,METAP1,CDK6,MTAP,ADD1,RAP1B,SMCHD1,MED29,AKAP8L,EDC3,CD81,GPM6A,GPC1,THOC3,EEIG2,NMRAL1,ADNP,LNX2,WDR77,RAB6A,SUPT3H,PPP1CB,RPL35,DYNLL1,TNPO3,GNB1,GGPS1,CHCHD3,UBE2S,VGLL4,CYB561,BLVRA,SP1,NOP16,MCM4,RHEB,SOCS5,EMC8,HS2ST1,RFC2,TRIP4,ZC3H7A,TMEM14B,GTPBP1,RBPJ,GNB1L,GPBP1L1,TXNRD1,KHDC4,E2F4,GTF2E2,ERLIN1,PPP2CB,WDR6,COPS2,PBDC1,TRAF6,DDX23,UBE2D1,MIR1-1,TRIM8,PRPF19,FEM1B,EIF3D,SMC4,PFKFB2,RPL4,NPM3,RETREG2,NXPE3,EGFL7,VIPR1,JUP,LMNA,RPLP0,CCND1,RBFOX2,RPS14,LDHA,RPL22,VKORC1L1,SH3BP4,STUB1,VAMP3,UBASH3B,RPS20,PTEN,SNX12,BMERB1,STK11,PPP1CC,THRAP3,ELOVL6,MSH6,PRDX4,RPS13,SFT2D2,TICAM1,ZNF787,LTBR,GEMIN7,TMEM101,COMTD1,RPL15,EEF1A1,CD151,EHBP1,TMEM91,TLE1,CALR,TMEM199,ORC5,GLO1,RER1,HIRA,EP300,CTBP1,NACC2,ADSS2,PAFAH1B1,GOSR2,ELK4,NEK7,CNPY3,TCEAL1,PPP5C,BST2,GTF2F1,FAM83B,SF3B4,FTSJ3,POLR1B,SLC38A1,RUSC2,PCCB,MLF2,KRAS,RERE,RTCB,FBXO11,DNAJB4,UCK2,RPL18,RANBP1,SUPT5H,NETO2,MAX,OAZ2,HPCAL1,ISG15,TRAF2,CRTC2,HOMER3,TRAPPC10,MAGED2,TLDC2,DCAF5,HSPB1,NT5C2,IQSEC1,UTP6,TSPAN5,UGDH,TMX2,STX17,RPRD1B,TCP11L1,RPA2,ACACA,HECTD1,MIR21,ING5,SETD3,SRC,SRPK2,RPS3,PSMC5,MFSD14B,CCDC174,CEP85,SPRED1,CHPF,ZSCAN25,RPS17,TMEM33,KDM4B,GSKIP,FKRP,TMEM50B,RAB13,ACOT13,TMEM165,TFRC,UGCG,RAP1A,SRFBP1,URM1,P2RY11,RPS16,TRAPPC3,SMAD4,USP15,RPS2,PGAM1,MZT2B,TMEM107,FAM168B,PRKD3,TBC1D24,DNAJC3,JADE1,BIRC2,KLF3,SLC25A3,FKBP10,AGTRAP,PGRMC1,B4GALT3,EIF4A2,MAD2L2,SUSD6,PAQR4,ABHD12,VPS72,S100A6,RPS9,YWHAZ,BRCA1,ILK,MIR363,PKP4,TM9SF4,CDC123,RPS29,MIR98,NAT9,MSL2,RPS27A,SLC25A5,ZYX,MRPS11,BAG2,SLC39A3,EXOSC3,SART3,RPS11,RBM12,ACTN4,FAF2,STPG4,AGK,EGLN3,RPL9,SDHAF2,BRD9,PEDS1,RB1CC1,HNRNPD,PDIA3,PIK3R1,HNRNPA1,FBXW7,MIR205,HELLS,INPPL1,WTAP,AGAP1,SHOC2,UBAP1,SEC22B,PIP5K1A,PDE8A,KLF12,RASGEF1C,KDELR2,ANKH,TMOD3,CTTNBP2NL,UBE2L3,PHTF2,CTNNA1,ENO1,GGCX,PAIP2,AP2A1,CNTNAP1,TAF5L,RALB,RHOBTB3,IFNAR1,TTC4,HUWE1,PTGES3,TMEM50A,FAF1,IGF1R,KLHL15,TSPAN17,SPSB3,MMACHC,KLHL26,SOD2,CCT5,TM4SF1,FCF1,MAP2K3,CGAS,MDM2,TNKS,MIR25,DLGAP4,NLRP1,MIR34A,BRD3,FAM53B,PMM2,MICB,DAG1,EEF1G,TIMM17A,UFL1,NGRN,MED13L,CSNK1A1,EIF4B,IL6ST,RPL10,ESR2,RNASEK,POLR2B,CMTR1,H2AZ2,RCL1,HNRNPC,LDHB,MYC,PSMD1,KANSL3,GXYLT2,NAB1,HNRNPF,BCL7B,GNA11,RPL31,FAM168A,MIR589,MIR206,PDHA1,TUBB4B,RPS23,GNAQ,EEF2,NUDCD3,RPS10,CDK17,SMUG1,GLRX,KCTD20,PABPC1L,SLC66A2,CRTAP,RPL6,QPCTL,XPO1,WDR3,LITAF,NLE1,DDX46,CSNK1G3,LEMD3,MIR7-1,WSB1,EGLN2,PLAGL1,TXNDC12,RNASEH1,CTSB,DYRK1A,NOPCHAP1,PPP2R5E,MACROH2A1,CALML5,B4GALT1,IGF2BP1,CARS1,CNNM4,PRKACB,PSMA5,NUP107,DHX9,CAPZA2,CCM2,EXOC3,DDX42,SNAPC5,RPSA,TP53,PLA2G12A,YIPF4,SNN,FZR1,KCTD3,TMED9,CAND1,STX6,MALSU1,RPL32,ITGA6,SSBP1,SLC39A10,TSNAX,GAPDH,API5,FTL,G3BP2,MCRIP2,RMND5B,SLC35F2,NUBP2,VAV2,MYL6,OTULINL,RBBP4,RPL7L1,SPINDOC,RPL19,DIO2,FAU,ARPP19,RPL37A,SYBU,AP2M1,TBC1D16,CUL3,SAMHD1,ZNF668,ETFA,G3BP1,LASP1,PCGF3,PCGF6,SIAE,ATF3,RPS24,ERP29,EZH2,WDR37,DSTYK,SPTAN1,RPL7,PHB1,DNM2,SLC43A2,SGMS1,RPLP1,HP1BP3,TSG101,CHST11,KDM2A,RHOG,ADAT1,NQO1,SLC35D1,LYZ,RSBN1L,CDIP1,UBXN6,PRDX1,ATG7,EMC6,CERS2,SLC5A6,FADS2,SIRT7,LRRC8D,MAVS,SQSTM1,GPX4,OPHN1,PTP4A2,CDK1,TTI2,MYL12B,ATG16L1,SAP30BP,EDF1,RPL13A,SEC63,CYRIB,PELP1,RTRAF,GSK3A,STK24,ZNHIT3,CCDC22,XPOT,DEDD,CTSD,AR,NONO,USP14,ATP5F1A,RUNX1,GALNT2,CTNND1,GLUL,HINT1,UAP1,SRP72,RAD23B,ILF2,PPME1,GFOD2,CCDC47,SLC29A1,EIF2B5,TOP1,SSU72,AIFM1,SEC23A,SLC2A1,DNAJC7,ISYNA1,CIDEB,RELL1,SSR3,STAU1,EYA3,UBE2D3,HNRNPA0,XRCC5,CREG2,SPATA2L,HSPA8,MRPS18A,DMTF1,RPL27A,SMIM13,FBXO22,NLGN2,RBM27,SPCS3,PLA2G15,DNAJB6,TMEM38B,MIR155,ZNF609,RPL28,PABPC1,UQCC2,KLHL23,SPTSSA,TOP3B,CCDC134,PCSK9,GFOD1,HMG20A,LANCL1,LRRC61,POLR2L,PPFIA3,S100A8,AGR2,ZDHHC14,YWHAB,EEIG1,TAX1BP3,CBR4,H2AC13,KDM1A,HSPA5,MIR29A,TOMM20,POLD2,ZNF326,GALNT1,SPTBN1,BLCAP,PLP2,ADRM1,RALA,CSTF3,SGTA,EIF2S2,RC3H2,CRLF3,SPOP,SNX5,PSMG3,PTPN11,SUB1,RNASET2,MAT2A,TIA1,RBCK1,KPNA2,L1CAM,RASL10B,MIR16-2,ATP2B4,SLC16A1,RPL3,RNF8,TAB2,SURF6,SELENOI,SYNCRIP,SNRNP70,AGPAT1,RPL10A,FAM20C,ZNF24,EDEM1,CMSS1 |
| 5.848e-11 | -23.56 | HK1 (hexokinase 1) | protein interactions | 3098 | 217 | 106 | 19454 | 5460 |
ENO2,VDAC2,SEC61B,RMDN3,BPIFB3,APEX1,RAB11A,MYC,ATG101,ZMPSTE24,FIS1,EXD2,LUM,AKAP1,EP300,P4HA2,HSPA8,PHB2,NSFL1C,RP2,STAU1,EMC1,STX7,GNB4,PXMP2,MTX2,TOMM22,PPT1,MAP2K1,PLAA,HEXB,ATP6V1A,MAGED2,COX14,MARCHF5,RAB5C,SYNJ2BP,CRTAP,AGR2,SKIC8,PEX3,PDCD10,HAX1,PCNA,VDAC1,KRAS,TMED7,TXNRD1,HEXA,ARFGAP1,RAF1,SOX2,PTRH2,EZH2,METAP2,UQCRC2,CCNF,SGTA,MGST3,VIRMA,GNAI2,AKT1,USP14,TUFM,KCNJ2,STK11,CDC73,SIRT7,BAP1,RPA3,RTN4,GRPEL1,TOMM20,UBA52,CFTR,UQCRC1,GTF3C4,RNF146,SSR1,RPA2,P3H1,CYC1,RARS1,ARL10,COMT,SDHB,AIFM1,PTPN1,RAC2,TES,ARF6,CAV1,SLC25A12,LMAN1,SLC25A46,ESYT1,POR,MAP1B,TGFBR2,RAB3B,FKBP8,ARF4,MTCH2,EEF1A1,FURIN,CAPN2 |
| 6.008e-11 | -23.54 | TNF (tumor necrosis factor) | protein interactions | 7124 | 323 | 145 | 19454 | 5460 |
RPL10A,DAG1,TPM3,PLEKHO1,MYL12A,G6PD,CAV1,FNDC9,RPS27L,SSBP1,RPL12,SYNCRIP,SRP14,UBE2N,SSMEM1,ALYREF,TAB2,RNF8,HSPA13,EEF1A1,AZI2,RPL15,TBK1,RPS13,RPL17,CAPZA1,RBCK1,RPL3,MAP1B,TCOF1,IGF2BP1,NRP1,RPS17,RPL26,ZCCHC12,TUFM,SLC25A1,TNFAIP3,RPL7A,ACP2,RPL22,TMOD3,TXN,RPL13A,SEC61A1,B4GALT1,RPS20,RPS12,OPTN,RPS3,TNFRSF1B,TUBA1B,KRT7,LMNA,STOM,CDC42,LRRTM2,CLU,HSPA5,RPL4,HSPB2,H2BC12,SQSTM1,UGDH,RPL27,BANF1,TMEM263,HNRNPD,STX1A,HSPB1,NQO1,RPL23,IKBKB,NCR3LG1,TRAF6,HNRNPA1,SPATA2,ICOS,LAMP2,PRDX1,RPL6,RPS10,RPL7,MAP1LC3A,NEO1,RPLP1,RPLP2,KRT8,RPL9,RPS23,OTULIN,SNRPE,AP2S1,TUBB4B,AQP3,TRAF2,EEF2,RPS4X,RPL28,RAB18,IFNG,HNRNPF,TNF,SEMA4C,S100A10,MYO1B,JAK1,RPS24,SRSF7,SCYL2,SLC25A5,HNRNPA2B1,PABPC1,NDUFA4,RPS26,HTRA2,FAS,MYO6,FBXW11,H1-10,S100A11,RPL39,RHEB,RPS29,TAMM41,DYNLL1,ACTB,TAB1,S100A6,VDAC2,NFKBIA,CYB5R3,PACRG,PIP4P2,MYL6,PPP1CB,NEK7,H1-5,TANK,G3BP2,UFL1,BIRC2,RAB5A,DDX5,VSIR |
| 6.440e-11 | -23.47 | MRPL22 (mitochondrial ribosomal protein L22) | protein interactions | 29093 | 212 | 104 | 19454 | 5460 |
SAP30,MARCKSL1,DLG3,HINT2,MRPS11,COX8A,ARGLU1,SRSF4,PSMD12,HNRNPA1,MRPL9,DDRGK1,MTRF1,MRPS26,RHOG,SKIC8,MRPL18,GATD3,RPL9,KCTD10,MRPL12,RPL27A,ACTL6A,MFAP1,PSMB7,HSPA8,RAB5A,NGRN,EXD2,PSMC1,HSCB,PSMD1,MRPL16,MYC,MTG2,AUH,PMPCA,RPS5,TAFAZZIN,MRPL13,FAU,TACO1,ESR2,RPL10,RPL19,MRPL23,PSMD4,PSMD6,LAMTOR3,DDX39A,AURKAIP1,METTL15,MTA3,FAM162A,MRPL11,MRPL47,MRPL33,MRPL51,MRPL36,NDUFS3,MRPL52,MRPL22,MEPCE,ZMYND11,GRSF1,MOV10,RPS2,SNRNP70,TMEM70,MYBL2,PRR3,SSBP1,RPL12,MALSU1,MRPL24,MRPL50,MRPL10,RBMS2,ATG16L1,SF3A1,SEC22B,MPV17,HEXIM1,MTRES1,PGK1,SYVN1,GFM1,SNAPC1,RPL27,MRPL17,FBXW7,MRPL41,RPL26,TUFM,PTTG1,UBE2H,DNAJC19,MRPS16,RC3H2,PPTC7,MRPL53,CCNF,OPTN,COPE |
| 6.520e-11 | -23.45 | negative regulation of cell motility | biological process | GO:2000146 | 396 | 177 | 18204 | 5365 |
MIR204,SIN3A,MEF2C,ING2,MIR129-1,MIR31,IL4,RGCC,PLCB1,LDLRAD4,MIR21,MIR146A,MIR149,IGFBP3,MIR185,EPHA4,MIR3173,GNRH1,MACIR,MIR223,ACVR1C,PADI2,MIR379,TP53INP1,ABHD6,MIR126,SFRP1,DDT,MIR132,MIR885,MIF,TMEM196,MIR10A,MIR449A,BST2,CCL28,CD200R1,MIR200C,ATP2B4,MIR29C,PTEN,SAP30L,HDAC5,MIR206,CTNNA1,CCL21,RGN,MIR20A,MIR320A,MIR497,MIR492,MIRLET7B,STK26,MIR221,MIR130A,DUSP3,CALR,SAP30,DPEP1,SPRED1,PDCD10,MIR9-1,RBBP4,HYAL2,AKT1,STARD13,RAP2B,SPINT2,MIR182,WASL,COL3A1,ADTRP,GREM1,MIR152,MIR92B,BMPR1A,MECP2,MIR335,ABHD2,AP1AR,MIR638,NFE2L2,MIR137,MIR29A,NF2,TIMP1,OSBPL8,ADGRG1,MIRLET7G,BRMS1,JUP,RAP2A,RNF20,STK24,MIR193A,PTGER4,MIR493,MIR218-1,CXCL13,MIR212,MIR551A,MIR503,PPARG,BMERB1,SVBP,CLIC4,MIR133B,MIR188,MIR34A,MIR15A,MITF,CYGB,TNFAIP6,GPR173,MIR1-1,SYNJ2BP,ADORA1,ADORA3,DAG1,RAP2C,VASH1,MMP28,THY1,MIR140,CD200,KRIT1,RNF41,KLF4,NHERF1,SEMG2,CCL2,MIR424,MIR338,MIR491,MIR16-1,CCL25,GADD45A,CYP1B1,GJA1,MIR214,CSNK2B,TRIB1,CDH11,CLDN3,DPP4,AIF1,CERS2,BRMS1L,MIR101-1,MIR24-1,CX3CL1,MIR1298,DUSP22,MIR640,STC1,MIR505,RBBP7,ADIPOQ,TNF,TMIGD3,ING1,DUSP1,CCN3,MIR145,CX3CR1,CXCL12,HMGB1,MIR495,MIR205,CORO1C,MIR361,DUSP10,ADIPOR1,STAP1,RHOB,EMILIN1,NOG |
| 6.702e-11 | -23.43 | NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8) | protein interactions | 4702 | 186 | 94 | 19454 | 5460 |
MAX,HSDL2,CYB5R1,EEF2,NDUFS6,PDHA1,NDUFA12,NDUFB5,HSPD1,NDUFA4,SDHC,CHCHD2,G3BP1,VDAC1,IMMP2L,NDUFV2,NDUFB8,PHB1,CORO1C,COPS2,NDUFS8,CNTROB,UQCRH,EGLN3,COX14,RMND1,TOMM22,PRDX3,NDUFAF3,PPARG,ATP5PO,NDUFA5,PIH1D1,HSPA8,HADHA,NDUFS2,PHB2,PSMC1,FMC1,NDUFB6,NDUFB7,MYC,PSMD1,FAS,HTRA2,VDAC2,LMBR1L,CCDC90B,CYB5R3,ATP5F1B,ACTB,PSMD6,CHCHD3,PARL,KBTBD4,MTCH2,NDUFA2,APOO,NDUFS3,SLC25A24,SFXN1,HAPSTR1,GNG5,CLPB,EMC2,CAMK2G,TRIM63,POR,AIFM1,NDUFB4,COX4I1,NDUFA1,SPPL3,PLGRKT,SLC25A12,TIMMDC1,UQCRC1,PGK1,NDUFC2,PDHB,KDM1A,SLC25A51,FBXW7,NDUFB10,ATP5F1A,TUFM,HMOX2,ATP1B3,UBE2H,CCNF,OPTN,UQCRC2,PTPMT1,CHCHD6 |
| 6.721e-11 | -23.42 | BNIP1 (BCL2 interacting protein 1) | protein interactions | 662 | 133 | 73 | 19454 | 5460 |
STX8,RINT1,HAPSTR1,STX18,CTNNBL1,SLC7A14,SRPRB,CCDC47,SNAP29,PPP2R1A,DNAJC25,TMEM31,IFT57,STIM1,CRELD1,STX12,TAF2,OTULIN,TSPAN3,PTPN1,KCNA2,CAMLG,HSD17B11,STX5,ANKRD46,DNAJC1,STX6,FAM174A,MARCHF5,SKIC8,PTGER4,STX1A,VPS4A,BCL2L1,JAGN1,TMX2,CXCR4,SNAPC1,GRAMD2B,SQSTM1,DERL1,NAPG,GOSR1,LPAR1,STX7,SEC22B,BET1,PGRMC1,TSHR,OTULINL,ST7,MED23,LMNA,GPR35,STOM,USE1,CHRNB2,LMBR1L,ELOVL4,RETREG3,SEC61B,TM4SF19,TRIM32,CREB3,SCN3B,VAMP5,GLT8D2,STX16,CYB561,RIC3,EXOC8,NAPA,SCFD1 |
| 6.733e-11 | -23.42 | organelle subcompartment | cellular component | GO:0031984 | 1528 | 556 | 19108 | 5553 |
FLRT3,PSEN2,TLCD3B,RAB29,CHPF2,STBD1,ATP8A1,SPCS2,RNF133,MS4A7,ELOVL4,TMEM38B,TMEM39A,GGCX,CCDC186,PML,ILVBL,BACE1,CD2AP,CYP4F12,SYS1,CYP39A1,GJA1,EXT1,MSMO1,RDH10,SCAMP2,ST3GAL4,DHRS3,RAB13,TLR7,DNAJC25,USP6NL,NDST1,CCDC47,SEC63,EMC4,SSR2,UBIAD1,PLAAT3,VAMP7,MOB4,ELOVL6,RAB31,ARL6IP5,C2CD2L,FITM2,FITM1,B4GALT6,LRRC8B,DRD1,CYP2C9,B4GALT7,MRLN,IZUMO1,RDH12,TMEM147,LMBRD1,MACO1,SPCS3,CYB561D2,FAM91A1,OSBP,UFD1,RAB1B,GOSR1,IFI27,TAS2R16,SRD5A3,HSPA5,ZDHHC4,EMC1,SRXN1,RTCB,STX10,VAPB,EMC6,STT3A,ERG28,HACD1,FKBP2,REEP4,DHRS7B,CYP26A1,SEC22A,LAP3,RAB32,UBA52,SLC39A9,VPS54,CHRM3,STX5,DERL2,ARL5B,CYP2F1,MYORG,ERO1A,MARCHF4,RAB6A,FURIN,CIDEB,SLC35B4,GALNT2,SEC11A,RSAD2,CYP4F22,SDCBP,PIGW,SHISA2,SRI,SCFD1,TMEM115,ELOVL3,VRK1,RP9,PREB,GORASP2,TRAM1L1,FMO2,USE1,TMX4,REEP6,CLVS1,SLC35B3,MOXD1,HACD2,LRRC8D,SLC51A,TRAPPC6B,WASL,PNPLA8,TMCC1,RETREG3,TMEM97,AHCYL1,CD59,MINAR2,KDSR,SLC35A2,RB1CC1,CYP3A43,RAB11A,SERINC1,SRPRB,VMP1,ORMDL3,FOLR1,NSDHL,MARCHF9,FUT8,FA2H,TAPT1,ABHD4,SEC22C,RDH11,CLN8,BSCL2,RPL27,PCYT1B,BCAP29,KPNA2,SELENOK,ARFIP1,DERL1,GOLGA5,SEC61G,TRAM2,GDPD3,RAB18,BOK,SPCS1,VTI1B,ACER3,CYP1B1,ELOVL7,CHPF,PTGDS,RNF121,LRAT,CYB5R3,FDFT1,VAMP2,HSD17B3,FKBP8,EMC10,CYP21A2,PTPN1,PTDSS1,IFI6,YIPF4,RPS26,FAM8A1,RGP1,NSFL1C,FATE1,TRAF2,MYRF,KDELR1,RPN1,EVA1A,PDIA3,PIGA,CYP2C8,JKAMP,PICK1,AP1S2,MX1,SEC22B,CYP17A1,PROS1,NFE2L1,NOS1AP,UBAC2,B4GALT1,GRIA2,NCSTN,CLSTN3,SLC66A2,TRAPPC6A,FAXDC2,TMED4,OS9,CYB5R4,CYP3A5,LYPLA2,ALG2,RNF103,GRIA1,CARD19,RNF139,CYP4V2,ARCN1,SLC30A7,TSPO2,XXYLT1,PGAP3,INSIG2,SSR1,SFTPA1,ANXA7,CYP1A1,GOSR2,PLP2,RNF5,HSP90B1,NSG1,AGTRAP,LBR,TEX264,SEC61A1,ST3GAL2,TOR1AIP2,CAMK2G,GABARAPL2,SPTSSB,WDR83OS,PSEN1,FAF2,ZDHHC16,FLRT2,RAB14,RETREG1,MGAT4A,TRAM1,CYP2D6,ALG11,TAPBP,STIM1,TMEM33,GALNT1,ESYT1,STX18,FUT9,MOSPD1,RETREG2,TLR9,CNIH1,TM4SF20,APH1A,ACSL4,SCAMP5,DHRS4,HM13,FUT1,GPR37,SPPL3,PGRMC1,AGPAT1,ATG9A,CERS6,ARFGEF1,OPTN,FAF1,ATP6AP2,TMEM170A,CHST2,SEC61A2,RHOBTB3,POMT2,PEDS1,SC5D,HTRA2,SGMS2,RINT1,FCMR,RAB9A,TMEM87A,PTGES,DPAGT1,TMEM165,ELOVL1,HRAS,SELENOS,PTPN5,SEC13,PGAP2,TLR3,MPDU1,GAL3ST4,ALG5,TMEM106C,GJB1,B4GALT3,EXTL2,RPS28,GPAA1,LMBR1L,CASP4,XBP1,DOLK,SEC23A,SLC39A13,DPM2,CERS2,PSKH1,COG1,SSR3,NUS1,DHRS7,RAC2,PLEKHJ1,GOLGA7,COPZ2,OSBPL8,SGMS1,ZMPSTE24,DIO1,STX17,GOLPH3L,PLD3,GPR89A,STX8,TOM1L1,SFTPD,CYB5R1,PHETA2,TAB1,INPP5E,TMT1B,TAPBPL,MIA2,CREB3,SELENOI,SFTPC,RTN4,ABCB9,PIK3R1,SACM1L,CLIP3,SURF4,BFAR,TMX3,AGPAT5,STARD3NL,CNIH4,BAX,CYBC1,SEC62,AP1M1,TMED7,UGT1A1,MME,GNAI3,ERLIN1,SELENON,CFTR,PDIA6,TECR,POR,SELENOT,CALR,OCRL,TMEM174,SLC35D1,SLC30A5,CD1D,CYB5A,EDEM1,FMO1,TMX2,CYP7A1,EMC9,CDIPT,DDRGK1,MGST2,KRAS,SDR16C5,NOTCH2,OTULINL,AQP11,VCPIP1,APOO,LRRC8C,PSENEN,TMCC2,CYP2R1,MGAT4B,CSGALNACT2,ALOX5AP,CYB5B,CYP2C18,GJC1,CREB3L4,SIGMAR1,LMAN1,FKBP1A,KDELR2,FZD6,TLR8,MYO1B,UFL1,DUOXA2,YIPF5,G6PC3,SNAP25,TRAPPC4,WDR11,CHST7,CH25H,TMEM50B,PIGY,CYP4F8,FKBP1B,CDK1,ST6GAL1,CAMLG,TMBIM6,RPS29,PIGK,CLBA1,DLG1,SVIP,DNAJB2,CHID1,LPCAT3,SPTSSA,TRIQK,ERLIN2,CD4,DNAJB9,ATG101,EI24,SEC61B,STX16,JPH4,AZIN2,DMPK,TMEM14A,HMOX2,COPE,VAMP3,MEST,HACD4,SLC39A7,TMEM59,GABBR1,SLC37A4,CLVS2,EIF5A2,CALU,SAR1B,RNF41,PITPNB,PLEKHA8,GGTA1,PREPL,RNF26,RIC3,SYVN1,B2M,PIGC,CHST1,MARCHF5,TMEM203,EMC8,RCE1,TEX261,ZDHHC14,DIPK1A,DAD1,DPY30,RHEB,TUSC3,RAB2A,UBB,STX6,FADS2,ABHD12,IL15RA,ATL1,OST4,TMED5,BECN1,EMC2,RHOG,VKORC1L1,HSD11B1,RPS27A,ST3GAL1,RAB30,LYSET,PLPP6,MBLAC2,DEGS1,INPP5K,TMEM199,RETSAT,TMEM208,CDC42,PLN,KCNA2,JAGN1,BPNT2,SCD5,ATP2C1,CAV1,ORMDL1,AFTPH,MTDH,MGST3,SRPRA,CSGALNACT1,ZFAND2B,REEP3,TMED3,DNAJC1,FMO3,TESPA1,YIF1A,PYURF,BET1,GCC1,EPHX1,HACD3,TMED9,TMED1 |
| 6.809e-11 | -23.41 | PSMD4 (proteasome 26S subunit ubiquitin receptor, non-ATPase 4) | protein interactions | 5710 | 343 | 152 | 19454 | 5460 |
ZNF24,CENPP,PPM1D,PSMD7,H2AC4,CCDC92,USP15,ID1,AIFM1,SSBP1,PSMB1,PRNP,FZR1,MDM2,CDK9,INSIG2,TP53,KBTBD4,PSMB9,CAPZA2,TMEM31,CBX3,NUPR1,PSMC3,RAD23B,PSME1,MAP1B,ABCE1,FARSA,TRIM63,RBCK1,NEDD8,SEM1,HUWE1,PSMA5,FKBP8,MDC1,FBXO25,MEPCE,PSMB10,MRPL22,PSMB2,USP14,ATP5F1A,TXNIP,UBE2H,PSMA6,CCNF,STUB1,ALB,RPS20,PTEN,RPS12,PSMC5,ADRM1,VIRMA,UBB,SMURF1,UBA52,ATG16L1,PSMC4,PAAF1,CFTR,CCNA2,CDK7,UBLCP1,USE1,METTL14,RPA2,TCP11L1,HEXIM1,UBE2M,IDH3A,SOD1,RPA3,SNAPC1,BAP1,ITGA2,SQSTM1,DESI1,BCL6,WWP2,PSMD3,CTNNB1,DDRGK1,SIAH2,EIF3D,PSMD10,AQP4,RASSF8,PSMB4,PHB1,PSMB5,PSME2,MAP1LC3A,GJA1,DYNC1I2,HSP90AB1,DIRAS3,PPIA,EGLN3,B3GNT2,ISG15,GFPT1,KDELR1,SCHIP1,CYP2C9,PDIA6,UBE3A,HNRNPF,PSMA2,KRAS,PSMA1,FLOT1,AHCYL1,PSMD12,CCAR1,RPS27A,CUL2,PSMA4,ACO2,MYC,PSMD1,BRCA1,PSMD14,ATG3,RIT1,HSP90AA1,DIO2,PSMD6,ATP5F1B,PSMD4,ESR2,PSMB6,PSMB3,CRYAB,PSMB7,MFAP1,HERC3,NUBP2,PSMA3,HADHA,TXNL1,HSPA8,PITHD1,MRPL57,EEF1G,UFL1,PXMP2,RNF11,PSMC1,DDI1 |
| 6.897e-11 | -23.40 | extracellular vesicle | cellular component | GO:1903561 | 2278 | 795 | 19108 | 5553 |
FTH1,FBP1,LILRB4,AASDHPPT,OXSR1,CD63,IRF6,CLIC4,PRCP,ENO2,SSBP1,MIR26B,TMEM256,S100A11,CHMP5,TIMP1,GMDS,PPT1,WWP1,HBB,CNP,AHSA1,AKR7A2,YWHAB,EIF3E,LMAN1,AZGP1,SLC25A3,AKR1B1,VDAC1,CDK1,GPX3,MTAP,MIR638,RPS29,MIR194-1,RNASET2,ATP1A3,GABRB2,SVIP,RAB22A,NAA50,ADSS2,TXN,SNRPD2,STOM,UBE2D3,CDC42,SLC2A3,GNAQ,RPS14,VAMP8,SERPINI1,PSMA6,SNCG,GALNT4,ACAT1,GSTCD,SERPINB1,ICAM3,ACTR3B,PITPNA,TUBB4B,PRSS8,MIR16-1,MIR423,TMED9,GSTK1,JCHAIN,RHEB,GLO1,PRKACB,CD248,STK11,RAB2A,SOD1,PPIB,HUWE1,NME1,SNX3,CYFIP2,MIR125A,MIR101-1,RHOG,BLOC1S5,RPS9,NME2,MBLAC2,CACYBP,TF,CKB,PEBP4,VPS4B,TMBIM1,TNFSF13,KRT8,MIR23A,FABP4,DDT,H2AC13,GNA11,DDR1,DNPH1,RPS20,H3C1,MIR99A,LCP1,PGAM1,EPCAM,GAL3ST4,FLOT1,TSPAN3,KRT7,TSG101,RNASE1,RPS28,B4GALT3,YWHAH,PMP2,MIR100,RAC2,TOM1,AOX1,RPLP2,RPL23A,CTSC,H2BC14,MIRLET7C,GOLGA7,PSMB5,STAU1,ZMPSTE24,MIR34A,CSNK2B,ESD,PSMB9,AP2M1,PPFIA2,IFT172,HSPA8,MDH1,GPX4,ARHGAP1,TTR,MIR148A,CD38,MYL6,VPS4A,SNAP23,CAPZA2,SH3BGRL,RPL26L1,TXNRD1,CTNNB1,ATP6AP2,SNAPIN,HNRNPC,GLIPR2,PLAA,CUL3,MIR338,NECTIN2,DDAH2,CSE1L,MIR130A,CALR,CMBL,RPLP0,PROM1,SIT1,SEMA3C,FAS,PPP2R1A,PSMA1,GNPTG,ALPL,CAMP,RRAS2,MIR10B,RHOB,EIF4E,FAM3C,WWP2,SYT4,SPP1,S100A8,CYB5R1,EIF2S1,PSMD3,TPT1,PPIA,CXCL12,F2,MIR192,RAB4A,MBD5,CHI3L1,CAPZA1,MIR198,MGAT1,AP1M1,ST13,SNX18,BPGM,TOM1L2,PI15,MME,ABCB1,PRELP,CDH13,ACTR2,GGCT,RPS26,GBE1,BPIFB1,CD81,PDIA3,DPEP1,LUM,MIR29A,SERPINA3,PACSIN3,PAFAH1B2,DNAJC3,PYGM,IDE,GK2,RPL27,GSTA1,ANGPTL2,MPST,SRSF7,GSTO2,NAA16,MIR30E,GDPD3,BTG2,SFRP1,GAPDH,ANGPT1,FGL2,MIR126,SLC12A2,PSME1,GSTM3,PTGDS,AQP2,ITGB5,PBLD,HBA1,PSME2,ANXA4,STAMBP,TFRC,ATP6V1C1,PSMB1,ATP1B1,RPSA,H2AC7,HINT1,MIR1234,LAMP2,TXNDC17,UPK1A,GCNT3,CCT7,MIF,BST2,HEXB,FLRT2,SHMT1,CEACAM5,PRDX6,MGAT4A,ATP1A2,PPP1CB,GNG12,PRRC2A,RAB5A,CCT5,FKBP4,FAM168B,SOD3,SH3BP4,NCSTN,ADGRG1,OGN,RHOJ,FAH,LYPLA2,VAMP5,GNB3,RPL37A,DEFB1,RNF11,CPNE2,EHD1,FCN2,MIR20A,FBP2,HIRA,CYBRD1,CCT2,B4GAT1,SLC15A2,RUSC2,MIR106A,CTNND1,MIR29C,ARPC2,TUFM,APEH,VAMP7,RPL3,TOR1B,PAFAH1B1,ARPC3,H2AC25,TAGLN2,SLC16A1,PLCB1,FABP5,AIF1L,CFAP20,GNAI2,HEBP2,MIR106B,ATP1B3,CSRP1,GCA,PEBP1,CRYAB,PNP,SFN,RPL26,OLFML3,C1GALT1C1,RAB29,NCKAP1,RAP1B,TOR3A,AK2,ACP2,AKR1C1,MIR92B,PSMB4,PDCD10,USP14,MIR208A,MIR146A,PALS2,GSTP1,YWHAG,GSTA2,MIR619,MIR215,PRNP,SRI,CAB39,NEDD8,THRAP3,PABPC1,TCP1,ZNHIT6,SERPINB6,PDZK1IP1,EPS8,CCL28,CPE,FAM234A,LGALS3,OLA1,BPIFA2,THY1,RPS13,RUVBL1,RAB11A,TUBB,MIR24-1,FUT8,EEF1A1,NPC2,COMT,PRDX2,ATP5F1A,DUSP26,HNRNPA1,PSMA2,SCPEP1,RAB11B,PCNA,LAP3,CD58,S100A6,HSPD1,GMPPA,MIR152,RPS4X,LDHB,RAB6A,RAB3D,MIR222,MIR17,CSK,GNG2,SOD2,STK26,RPL12,DNAJB9,G6PD,CHID1,CRYM,UBE2V1,GFPT1,FAM20C,SLC2A1,PSMC5,TMEM59,CMPK1,SAMM50,MEST,ITGAV,TNIK,RUVBL2,ACTR1A,STK24,MIR342,SEPTIN7,NEU1,CRB3,PPFIA3,PLG,B2M,ICAM1,GPRASP3,SPTAN1,ATP6V1A,CHMP1B,F11R,GSTM2,PRKCA,PGA4,ARF4,CD14,GLUL,DAG1,MYO1B,RPL31,RAB1A,MIRLET7D,GNG5,CHMP1A,SELENOP,CTDSP1,RALB,H2AZ2,IDH1,HSP90AA1,RPS11,MYO6,NIBAN2,WASF3,GPM6A,PGM1,DLG1,RHCG,CDH11,MIR422A,GPT,RPL4,NAPG,PYGB,REG1B,RPS2,RAB19,SERPIND1,RAB8B,SRPRA,ACO1,TOLLIP,MGP,P3H1,GNB4,S100A10,CRABP2,SLC25A1,VTA1,SLC11A2,COL1A2,ALB,RPL24,CTSD,CLTRN,CD86,H2AC4,CCT8,MTMR2,PSMB6,UBB,CTSA,DPP4,ABHD8,MIR185,RAP2B,YWHAZ,ST3GAL1,SLC22A8,RPS27A,EMILIN1,SQSTM1,MAN1A2,SEC13,MIR23B,MIRLET7B,ATP1A1,IL6ST,CA2,RAB27A,TAX1BP1,ENPEP,NUDT9,ATP6V1G1,PADI2,SLC1A1,AKR1A1,LAMTOR1,PSMD7,GANAB,PEG10,LAT2,SRC,DDX23,CRYZ,LDHA,ABHD14B,PLD3,ALDH1A3,CHMP2B,RPS5,KLK3,ENDOD1,SORD,GPC4,ACSL4,RALA,PSMD12,ARF1,GNB1,SLC20A2,MIR30D,DES,PDCD5,AMY2B,LYPLA1,CSTB,ENO1,SFT2D2,GHITM,HNRNPL,RAB5C,SERPINA5,ARL15,CHMP2A,HNRNPK,RHOBTB3,PRKCB,RAB9A,UBE2N,RAB35,CHCHD3,MARCKSL1,SLC22A12,PDIA6,MIR9-1,ALYREF,WNT7A,GGH,CTSB,LYZ,YES1,GSTT2B,PPIC,CAPN1,HSPA13,MIR193A,CUTA,SLC35F6,ANP32B,CFL2,CAPG,H2AC6,GNPDA1,VPS28,PRDX1,UGP2,ACTA2,TNFAIP3,RARS1,GRID1,PDE8A,TOM1L1,MIR191,HEBP1,LAMB2,MIR197,RAN,EEF1G,VWF,CD47,UBE2V2,FASLG,ATP6V1D,MYL12B,BAX,CXCR4,GNAI3,MIR15A,NAPA,RPS16,H2AZ1,MARS1,SDC4,PLA2G15,PRDX4,UBL3,GLRX,TNFSF10,BLVRA,RAB3B,PSMA3,SMURF1,PABPC1L,RPL35A,CD274,SPTBN1,PROS1,RAP1A,TUBA1A,SERPINA1,SYPL1,PIP4K2C,PCBD1,CYRIB,SYNGR2,XPNPEP1,NHERF1,MIR1304,F9,GFUS,VMO1,MIR143,ITM2B,NUDT5,CHP1,MIR31,SAT2,UBXN6,RPL10A,CD79B,HSP90B1,FTL,H2AJ,ATP5F1B,GPC1,PHB1,MSN,LAMTOR3,CAPN2,MIR21,RPL28,DSTN,RAB14,CNTN1,MIR30A,GLOD4,STX7,CNDP2,CD9,PSMA5,CD46,HNMT,HGS,CYSTM1,B4GALT1,EFNB1,MACROH2A2,MIR107,LRRC57,SUB1,MIR193B,ANXA7,CST3,EEF2,RETN,MYL12A,ARL6,COTL1,DNAJC7,TOMM70,ARF6,MIR671,RPL22,ITGB8,SLPI,ACTB,SEMA5A,PRSS23,SERPINB9,RP2,MIR145,DNM2,SERPINC1,SLC38A1,PLSCR1,H2AC1,SLC22A6,TAX1BP3,RAB1B,GDI2,HTRA1,GNG7,HEXA,FBLN5,DICER1,CPNE1,UGDH,IDH2,ATP8A1,MACROH2A1,AGAP2,STXBP1,RAB3A,PSMA4,TPM3,MMP9,KIF3B,MAT2B,CD2AP,FSTL1,CRYL1,CRTC2,RAB13,SCAMP2,ALDH1L1,H2AX,SEMG2,RACGAP1,RPE,SPR,ENPP4,CLU,ACTN4,MIR223,HNRNPA2B1,GSTO1,MIRLET7I,RAP2C,MIR214,AHCYL1,SIAE,FGR,JUP,WASL,CD59,REG1A,RPS3,RPL23,ALCAM,HP,HSPB1,FOLR1,GNA14,TSPO,HSPA5,H2BC9,PSMB2,PSMB3,CFL1,IL18BP,MIR30B,RBP5,UBA52,CAND1,ACTR1B,FURIN,HSP90AB1,DDAH1,MIR221,PGK1,DDX5,CD40,HSPE1,SDCBP,EHD4,GSTT1 |
| 7.072e-11 | -23.37 | Processing of Capped Intron-Containing Pre-mRNA | REACTOME pathways | R-HSA-72203 | 247 | 126 | 10285 | 3229 |
SNRNP40,NUP35,CCAR1,SF3B6,CPSF1,CTNNBL1,SNRNP48,RBM17,SLU7,NUP153,HNRNPA1,CSTF3,NXT1,RBM22,RBM5,SNRPA,GTF2F1,THOC6,POLR2I,CDC5L,NUP107,DHX9,SNRNP27,DDX46,LSM8,SRSF7,SRSF10,SRSF2,EIF4A3,HNRNPK,NUP37,ALYREF,HSPA8,SNRPG,POLR2D,POLR2L,WBP11,PRPF4,ZMAT5,POLR2F,DDX42,MIR939,UPF3B,DDX23,THOC1,PRPF19,CSTF2T,MIR1234,CPSF4,SNRPA1,SNRPD1,HNRNPA2B1,BUD31,MIR636,MIR7-1,SF3B5,LSM2,LSM4,NUP50,SRSF1,HNRNPL,CDC40,GCFC2,LSM5,LSM6,SNRPD2,SNRPE,TXNL4A,THOC3,NUP62,POLDIP3,USP39,DDX39B,NCBP2,SNRPD3,PAPOLA,HNRNPH2,MAGOHB,DDX5,CHTOP,THOC2,TFIP11,NUP42,SF3B4,SNRNP70,SMNDC1,METTL14,POLR2C,CPSF2,CLP1,SNRPB2,DHX38,DDX39A,SF3A1,SUGP1,ELAVL2,PPWD1,ZCRB1,TRA2B,SF3B1,POLR2G,PRCC,FYTTD1,PQBP1,SNRPB,GTF2F2,HNRNPA0,WTAP,POLR2B,EIF4E,DHX16,MAGOH,CWC15,PRPF31,SNRPN,HNRNPD,ZC3H11A,SRSF4,LSM3,CASC3,HNRNPF,CD2BP2,PPIH,HNRNPC,DHX15,DNAJC8 |
| 7.163e-11 | -23.36 | PMPCA (peptidase, mitochondrial processing subunit alpha) | protein interactions | 23203 | 377 | 164 | 19454 | 5460 |
NDUFAF4,CLIC4,DES,MRPL23,MTM1,ATP5F1B,PRDX2,MRPL13,DLST,MTG1,TACO1,H1-1,RIT1,BOLA1,MRPS25,MRPL16,CUL3,HNRNPAB,TXNRD2,PYCR1,MTG2,FMC1,MRPS7,OXCT1,PHB2,DUSP26,NDUFS2,HADHA,SDHAF4,ATP5IF1,NDUFA5,ATP5PO,MRPS18A,MRPL12,NDUFAF3,PRDX3,DHRS4,LAP3,PNPLA8,NDUFS8,HNRNPL,COPS2,GATD3,HDHD5,FBXO32,PHB1,DEFB1,PPM1K,MRPS26,FKBP4,RHOG,GSTO1,MRPL18,ACP6,MRPL9,NDUFV2,MRPS35,STOML2,MTRF1,CLPX,HNRNPDL,MRPS17,ATP5F1D,KGD4,ETFA,GUK1,KRAS,CHCHD2,COX8A,HINT2,PREPL,UQCC2,HSPD1,NDUFA12,PDHA1,NDUFS6,NUDT19,CCS,ETFB,HSDL2,SUCLG2,TXNDC12,CTSB,ACAT1,MRPS28,MRPL53,FXN,OAT,MRPS16,DNAJC8,TUFM,GMPS,MTPN,ATP5F1A,PYCR2,NDUFAF2,POLDIP2,MRPL20,CRYZ,GRPEL1,MRPL40,MRPL41,NME4,PDHB,MRPL17,PRDX6,GFM1,DLAT,TWNK,MAIP1,MTRES1,GSTP1,METTL14,GHITM,IDH2,QRSL1,PAK5,SPRYD4,MRPS34,RPA2,UQCRC1,MRPL10,SPR,COQ8B,MRPL24,MRPS23,SLC25A12,MALSU1,DBT,ATP5PD,MRPL50,MGME1,COX4I1,AIFM1,COQ8A,MRPS9,CHCHD1,COX5A,GRSF1,MPST,ABHD10,FASTKD5,MRPL22,MRPS18C,HSPE1,MRPS33,PDE12,HSD17B10,THG1L,MRPS18B,ATP5PF,MRPL52,CCDC69,MRPL49,BMPR2,NDUFS3,BCS1L,METTL15,GLRX5,HADH,PPIF,NDUFA2,MRPL47,ATP5PB |
| 7.222e-11 | -23.35 | MAVS (mitochondrial antiviral signaling protein) | protein interactions | 57506 | 285 | 131 | 19454 | 5460 |
MFN1,SLC25A46,USP2,MUL1,CDCA3,RAC2,TNKS,KRR1,ARL10,PTPN1,AIFM1,TLR1,PLGRKT,TOMM70,RPL35A,SOX9,ZDHHC4,DDX39A,TP53,MTCH2,TBK1,PSMC3,SBK2,VAC14,SFXN1,RIGI,FKBP8,TNKS2,TICAM1,RAB3B,RNF115,PRKACB,C9orf72,MAPRE1,CISD1,SGTA,EIF2AK2,CCNF,OPTN,SRC,TRAF1,SMURF1,MGST3,KCNIP3,CFTR,CDC42,SH3GLB2,PDCL,RNF146,SAMM50,RPA2,RAB9A,SQSTM1,MAVS,RNF34,IRF3,PML,SOD1,RPA3,TOMM20,SLC25A51,SLC7A1,YKT6,IRF7,IFIH1,MARCHF5,RAB5C,PEX3,HAX1,TRAF6,RHOG,IKBKB,USP46,WDR82,MAP1LC3A,FBXO32,TRAF3IP3,DNM2,RAB35,COX14,NUP35,PPIA,KCTD10,RHOH,FAF2,TRAF2,CSNK1E,RAB6B,BZW2,RAB4A,PTRH2,BAG2,TRIM21,HECTD3,SAR1B,RUVBL1,USP30,DHX16,ARL5B,OTUD7B,GPR17,RAB11A,HTRA2,NLRP3,FIS1,PSMD14,RMDN3,NFKBIA,GNB1,ESR2,NDFIP1,TAX1BP1,STAT1,TIMM29,RND2,MTX2,TOMM22,RAB5A,AKAP1,STK26,BIRC2,HSPA8,EXD2,TACR3,ARMCX2,FBXL4,PXMP2,PHB2,RNF5,CNTN1,HSCB |
| 7.245e-11 | -23.35 | RAS | prosite domains | PS51421 | 60 | 41 | 12186 | 3388 |
RAP2A,HRAS,RRAS2,AGAP1,RAB1A,RAB27A,RAB30,RAB3A,KRAS,RALB,MRAS,RASL10B,RIT2,RAP1B,DIRAS3,RASD1,RAB33B,RALA,RERG,RASL11A,RASL12,RIT1,RAB3D,RHOG,DIRAS2,RAB13,RHOJ,RAP1A,RAP2B,ERAS,DIRAS1,RHEB,RAP2C,RAB37,RASL10A,RAB29,RHOH,RND3,RAB18,RAB6A,AGAP2 |
| 7.309e-11 | -23.34 | TIMMDC1 (translocase of inner mitochondrial membrane domain containing 1) | protein interactions | 51300 | 215 | 105 | 19454 | 5460 |
MFSD14B,REEP6,SPOP,ARL6IP6,TUFM,NDUFB10,GJB2,CSTF3,CYP4F12,RAB14,SLC1A1,APOC4,VAMP3,CYRIB,DRAM1,RPA2,IDH2,SAMM50,SLC35F6,TPT1,NINJ1,CLEC12B,SLC25A51,VIPR1,NDUFC2,TMEM126B,MAIP1,RPA3,ORMDL1,IFNA2,SLC2A1,TMEM199,TMEM144,STX6,DUOXA2,SLC25A12,ANKRD46,LDLR,AIFM1,PTPN1,NDUFB4,COX4I1,TMEM31,NDUFS3,UBIAD1,MGARP,APOO,YIPF4,TIMM8A,MTCH2,FASTKD5,DUSP21,RIGI,DUSP19,TNFSF8,DNAJC30,UNC50,YIF1A,SFXN1,SLC35E4,THTPA,COX6B1,NDUFB6,CYB561D2,APLNR,ATP6AP2,NDUFAF4,PARL,TVP23B,LMBR1L,CCDC90B,APOC2,NDUFA5,VAPB,NDUFAF3,NDUFS2,PHB2,TMEM203,AKAP1,PEX3,NDUFB8,SCAMP5,FAM20B,DDRGK1,FATE1,MARCHF5,EGLN3,NDUFS8,RMND1,NUP35,MFSD5,DUSP6,NDUFA12,STX12,TMEM14B,HGS,AQP3,FAF2,TMEM176A,CSTF2T,RBM12,IMMP2L,ARL5B,NDUFB5,NDUFA4 |
| 7.524e-11 | -23.31 | negative regulation of locomotion | biological process | GO:0040013 | 413 | 183 | 18204 | 5365 |
MIR188,MIR133B,ST6GAL1,CLIC4,SVBP,BMERB1,SYNJ2BP,GPR173,MIR1-1,TNFAIP6,CYGB,MITF,MIR15A,MIR34A,MMP28,VASH1,RAP2C,DAG1,ADORA3,ADORA1,KLF4,RNF41,KRIT1,CD200,MIR140,THY1,NFE2L2,MIR137,MIR638,ABHD2,AP1AR,MIR335,MECP2,BMPR1A,MIRLET7G,ADGRG1,OSBPL8,TIMP1,NF2,MIR29A,MIR193A,STK24,RAP2A,RNF20,JUP,BRMS1,PPARG,MIR503,MIR551A,MIR212,MIR218-1,CXCL13,MIR493,PTGER4,ADIPOQ,TNF,RBBP7,MIR505,STC1,MIR640,DUSP22,CX3CL1,MIR1298,MIR24-1,MIR101-1,BRMS1L,CERS2,MIR145,CX3CR1,CCN3,DUSP1,ING1,TMIGD3,CORO1C,MIR495,MIR205,HMGB1,CXCL12,NOG,HDAC6,EMILIN1,RHOB,STAP1,ADIPOR1,DUSP10,MIR361,CCL2,SEMG2,NHERF1,MIR16-1,MIR491,MIR338,MIR424,MIR214,GJA1,CYP1B1,GADD45A,CCL25,AIF1,DPP4,CLDN3,CDH11,TRIB1,CSNK2B,ACVR1C,MIR223,MACIR,GNRH1,MIR3173,EPHA4,MIR185,SFRP1,MIR126,ABHD6,TP53INP1,MIR379,PADI2,MIF,MIR885,DDT,MIR132,MIR449A,MIR10A,TMEM196,SIN3A,MIR204,MIR129-1,ING2,MEF2C,LDLRAD4,PLCB1,RGCC,IL4,MIR31,IGFBP3,MIR149,MIR146A,MIR21,PDCD10,SPRED1,DPEP1,SAP30,CALR,DUSP3,HYAL2,RBBP4,MIR9-1,COL3A1,WASL,SPINT2,MIR182,RAP2B,STARD13,AKT1,MIR92B,MIR152,SEMA5A,GREM1,ADTRP,PTEN,MIR29C,ATP2B4,MIR200C,CD200R1,NRP1,CCL28,BST2,HDAC5,SAP30L,MIR20A,RGN,MIR320A,GHRL,CCL21,CTNNA1,MIR206,MIR130A,MIR221,STK26,MIRLET7B,ARRDC3,MIR492,MIR497 |
| 7.525e-11 | -23.31 | proteasome-mediated ubiquitin-dependent protein catabolic process | biological process | GO:0043161 | 297 | 140 | 18204 | 5365 |
SMURF1,COP1,PSMB10,CUL3,SPOP,HECTD1,UFD1,KLHL22,KLHL3,ZNRF1,RHOBTB3,UBE2B,TRIM3,RNF187,PSMD1,MAEA,PSMB11,WWP1,ANAPC2,MTM1,FBXO44,PSMB2,UBE2S,ECRG4,TRIM26,CSNK1A1,IFI27,UBE2H,FBXO7,PSMB6,NFE2L2,CUL2,RNF139,SIAH1,RBCK1,FBXO22,FAF1,PSMB9,SPSB3,KCTD17,ANAPC15,TRIP4,PPP2CB,RNF122,HECTD3,PSMA6,PSMB4,CRBN,UBE2A,DDIT3,FBXL7,PELI1,RNF34,SPOPL,MDM2,DTL,FBXL3,CDC26,WWP2,UBE3A,CDC16,CDC23,PSMB5,FBXL14,ANAPC4,TRIM45,UBE2D3,PSMB7,ANAPC16,ZFAND2B,CDC20,ADRM1,FZR1,FAF2,RAD23B,SPSB1,PSMB3,CCNF,PLAA,PSMB1,PSMC3,SKP1,RNF10,TOPORS,FBXO3,UBE2D1,UBE2N,PSMD14,PSMC5,USP14,FBXW4,FBXL19,RMND5B,ANAPC11,PML,GSK3A,FBXW11,PSMA3,SYVN1,PSMD7,RNF126,DERL1,UBXN2B,TNFAIP1,BFAR,FEM1A,STUB1,PSMD4,PSMC1,SIAH2,FEM1B,ANAPC13,NSFL1C,AKT1,SH3BGRL,FBXW7,PSMA1,PSMD3,FEM1C,DCAF11,UBE2W,APPBP2,PSMD6,ARMC8,KLHL15,PSMA4,ZFAND2A,FBXO9,KCTD10,PSMA5,PSMD12,GID4,FBXO31,GID8,CTNNB1,PSMC4,BIRC2,KBTBD6,FBXL4,PSMA2 |
| 7.613e-11 | -23.30 | extracellular organelle | cellular component | GO:0043230 | 2279 | 795 | 19108 | 5553 |
RPS16,H2AZ1,SDC4,MARS1,UBL3,PRDX4,PLA2G15,BLVRA,TNFSF10,GLRX,PSMA3,RAB3B,PABPC1L,SMURF1,RPL35A,SPTBN1,PROS1,CD274,TUBA1A,RAP1A,SYPL1,SERPINA1,PCBD1,PIP4K2C,XPNPEP1,SYNGR2,CYRIB,MIR1304,NHERF1,F9,VMO1,GFUS,MIR143,MIR31,CHP1,NUDT5,ITM2B,SAT2,UBXN6,HSP90B1,CD79B,RPL10A,FTL,H2AJ,GPC1,ATP5F1B,PHB1,LAMTOR3,MSN,CAPN2,RAB14,RPL28,DSTN,MIR21,MIR30A,GLOD4,CNTN1,CNDP2,STX7,PSMA5,CD9,HNMT,CD46,HGS,B4GALT1,CYSTM1,MACROH2A2,EFNB1,MIR107,LRRC57,SUB1,MIR193B,MYL12A,ARL6,RETN,EEF2,CST3,ANXA7,COTL1,TOMM70,DNAJC7,ARF6,MIR671,SLPI,ITGB8,RPL22,ACTB,PRSS23,SEMA5A,SERPINB9,MIR145,RP2,DNM2,PLSCR1,SLC38A1,SERPINC1,SLC22A6,H2AC1,TAX1BP3,GDI2,RAB1B,HTRA1,HEXA,GNG7,DICER1,CPNE1,FBLN5,ATP8A1,IDH2,UGDH,MACROH2A1,STXBP1,AGAP2,PSMA4,RAB3A,TPM3,MAT2B,KIF3B,MMP9,CD2AP,FSTL1,CRTC2,CRYL1,RAB13,SCAMP2,ALDH1L1,H2AX,RACGAP1,SEMG2,RPE,CLU,ACTN4,HNRNPA2B1,MIR223,ENPP4,SPR,MIRLET7I,GSTO1,MIR214,RAP2C,JUP,FGR,SIAE,AHCYL1,WASL,CD59,RPL23,RPS3,REG1A,FOLR1,HSPB1,HP,ALCAM,GNA14,TSPO,H2BC9,HSPA5,PSMB2,CFL1,PSMB3,RBP5,UBA52,MIR30B,IL18BP,CAND1,FURIN,ACTR1B,HSP90AB1,MIR221,DDAH1,CD40,DDX5,PGK1,SDCBP,EHD4,HSPE1,GSTT1,DNAJB9,RPL12,CHID1,CRYM,G6PD,UBE2V1,GFPT1,SLC2A1,FAM20C,TMEM59,PSMC5,MEST,ITGAV,SAMM50,CMPK1,TNIK,RUVBL2,STK24,ACTR1A,SEPTIN7,MIR342,NEU1,PLG,PPFIA3,CRB3,GPRASP3,ICAM1,B2M,ATP6V1A,CHMP1B,SPTAN1,GSTM2,F11R,PRKCA,GLUL,ARF4,CD14,PGA4,DAG1,MYO1B,RPL31,MIRLET7D,RAB1A,CHMP1A,GNG5,RALB,CTDSP1,SELENOP,HSP90AA1,IDH1,H2AZ2,RPS11,GPM6A,PGM1,WASF3,NIBAN2,MYO6,DLG1,RHCG,GPT,MIR422A,CDH11,NAPG,PYGB,RPL4,RPS2,REG1B,RAB19,ACO1,SRPRA,RAB8B,SERPIND1,TOLLIP,P3H1,MGP,GNB4,CRABP2,S100A10,SLC25A1,VTA1,COL1A2,SLC11A2,CTSD,RPL24,ALB,H2AC4,CD86,CLTRN,CCT8,MTMR2,PSMB6,UBB,CTSA,DPP4,ABHD8,RAP2B,MIR185,RPS27A,ST3GAL1,SLC22A8,YWHAZ,SQSTM1,EMILIN1,MAN1A2,MIR23B,SEC13,MIRLET7B,ATP1A1,IL6ST,RAB27A,CA2,TAX1BP1,ENPEP,PADI2,ATP6V1G1,NUDT9,SLC1A1,GANAB,PSMD7,LAMTOR1,AKR1A1,PEG10,SRC,LAT2,CRYZ,DDX23,LDHA,ALDH1A3,CHMP2B,PLD3,ABHD14B,KLK3,RPS5,SORD,ENDOD1,GPC4,ACSL4,GNB1,ARF1,RALA,PSMD12,DES,MIR30D,SLC20A2,LYPLA1,AMY2B,PDCD5,GHITM,ENO1,SFT2D2,CSTB,RAB5C,HNRNPL,SERPINA5,ARL15,RHOBTB3,HNRNPK,CHMP2A,RAB9A,PRKCB,RAB35,CHCHD3,UBE2N,MIR9-1,PDIA6,SLC22A12,MARCKSL1,WNT7A,ALYREF,CTSB,GGH,LYZ,YES1,GSTT2B,PPIC,MIR193A,HSPA13,CAPN1,SLC35F6,CUTA,ANP32B,CFL2,H2AC6,GNPDA1,CAPG,ACTA2,UGP2,PRDX1,VPS28,TNFAIP3,TOM1L1,MIR191,PDE8A,GRID1,RARS1,HEBP1,MIR197,LAMB2,VWF,RAN,EEF1G,CD47,UBE2V2,FASLG,ATP6V1D,MYL12B,BAX,CXCR4,NAPA,MIR15A,GNAI3,ABCB1,PRELP,ACTR2,CDH13,GGCT,RPS26,GBE1,PDIA3,BPIFB1,CD81,LUM,DPEP1,PACSIN3,SERPINA3,MIR29A,PAFAH1B2,DNAJC3,PYGM,IDE,GK2,MPST,ANGPTL2,GSTA1,RPL27,MIR30E,SRSF7,GSTO2,NAA16,SFRP1,BTG2,GDPD3,FGL2,ANGPT1,GAPDH,SLC12A2,MIR126,PSME1,GSTM3,PBLD,ITGB5,AQP2,PTGDS,PSME2,HBA1,TFRC,STAMBP,ANXA4,ATP6V1C1,ATP1B1,PSMB1,RPSA,H2AC7,MIR1234,HINT1,TXNDC17,LAMP2,UPK1A,GCNT3,MIF,CCT7,FLRT2,BST2,HEXB,SHMT1,CEACAM5,ATP1A2,MGAT4A,PRDX6,GNG12,PPP1CB,PRRC2A,RAB5A,CCT5,FKBP4,SOD3,SH3BP4,FAM168B,ADGRG1,NCSTN,VAMP5,FAH,LYPLA2,OGN,RHOJ,RPL37A,GNB3,DEFB1,RNF11,MIR20A,FCN2,EHD1,CPNE2,FBP2,HIRA,CYBRD1,CCT2,RUSC2,SLC15A2,B4GAT1,MIR29C,CTNND1,MIR106A,TUFM,ARPC2,PAFAH1B1,RPL3,TOR1B,VAMP7,APEH,H2AC25,ARPC3,TAGLN2,SLC16A1,AIF1L,FABP5,PLCB1,GNAI2,CFAP20,HEBP2,MIR106B,GCA,PEBP1,CSRP1,ATP1B3,CRYAB,RPL26,PNP,SFN,C1GALT1C1,RAB29,OLFML3,NCKAP1,TOR3A,RAP1B,ACP2,AK2,PSMB4,AKR1C1,MIR92B,USP14,PDCD10,MIR208A,MIR146A,PALS2,GSTP1,YWHAG,GSTA2,MIR215,MIR619,PRNP,SRI,CAB39,PABPC1,THRAP3,NEDD8,TCP1,ZNHIT6,SERPINB6,EPS8,PDZK1IP1,CPE,CCL28,BPIFA2,OLA1,LGALS3,FAM234A,THY1,RPS13,RAB11A,RUVBL1,MIR24-1,TUBB,FUT8,COMT,EEF1A1,NPC2,ATP5F1A,PRDX2,SCPEP1,RAB11B,HNRNPA1,PSMA2,DUSP26,PCNA,S100A6,LAP3,CD58,HSPD1,GMPPA,RPS4X,MIR152,LDHB,RAB3D,RAB6A,MIR222,MIR17,CSK,STK26,SOD2,GNG2,AASDHPPT,FTH1,FBP1,LILRB4,CD63,OXSR1,IRF6,CLIC4,ENO2,PRCP,SSBP1,TMEM256,MIR26B,CHMP5,S100A11,TIMP1,WWP1,PPT1,GMDS,CNP,HBB,AHSA1,YWHAB,AKR7A2,EIF3E,AZGP1,LMAN1,SLC25A3,AKR1B1,VDAC1,GPX3,CDK1,MIR638,MTAP,RPS29,MIR194-1,SVIP,ATP1A3,RNASET2,GABRB2,NAA50,RAB22A,STOM,UBE2D3,SNRPD2,TXN,ADSS2,GNAQ,SLC2A3,CDC42,RPS14,VAMP8,SNCG,PSMA6,SERPINI1,GSTCD,ACAT1,GALNT4,ICAM3,SERPINB1,PITPNA,ACTR3B,MIR16-1,TUBB4B,PRSS8,TMED9,MIR423,GSTK1,JCHAIN,GLO1,RHEB,PRKACB,STK11,CD248,RAB2A,SOD1,NME1,PPIB,HUWE1,MIR125A,CYFIP2,SNX3,MIR101-1,BLOC1S5,RHOG,CACYBP,MBLAC2,NME2,RPS9,CKB,TF,VPS4B,PEBP4,MIR23A,KRT8,TMBIM1,TNFSF13,FABP4,DDT,GNA11,H2AC13,RPS20,DNPH1,DDR1,LCP1,H3C1,MIR99A,FLOT1,GAL3ST4,EPCAM,PGAM1,KRT7,TSG101,TSPAN3,YWHAH,B4GALT3,RNASE1,RPS28,PMP2,MIR100,TOM1,RAC2,CTSC,RPL23A,AOX1,RPLP2,MIRLET7C,H2BC14,GOLGA7,PSMB5,STAU1,ZMPSTE24,ESD,CSNK2B,MIR34A,AP2M1,PSMB9,IFT172,PPFIA2,MDH1,HSPA8,ARHGAP1,GPX4,CD38,MIR148A,TTR,VPS4A,MYL6,SNAP23,SH3BGRL,CAPZA2,ATP6AP2,CTNNB1,TXNRD1,RPL26L1,GLIPR2,HNRNPC,SNAPIN,PLAA,NECTIN2,DDAH2,CSE1L,MIR338,CUL3,CALR,MIR130A,CMBL,RPLP0,PROM1,PPP2R1A,SEMA3C,FAS,SIT1,GNPTG,PSMA1,CAMP,ALPL,RRAS2,WWP2,FAM3C,RHOB,EIF4E,MIR10B,SPP1,SYT4,CYB5R1,S100A8,PSMD3,EIF2S1,CXCL12,PPIA,TPT1,MIR192,F2,CHI3L1,MBD5,RAB4A,CAPZA1,MIR198,MGAT1,AP1M1,ST13,BPGM,SNX18,MME,PI15,TOM1L2 |
| 7.613e-11 | -23.30 | extracellular membrane-bounded organelle | cellular component | GO:0065010 | 2279 | 795 | 19108 | 5553 |
SUB1,LRRC57,MIR193B,ANXA7,EEF2,CST3,RETN,MYL12A,ARL6,DNAJC7,TOMM70,COTL1,CD46,HNMT,CYSTM1,B4GALT1,HGS,EFNB1,MACROH2A2,MIR107,CAPN2,MSN,LAMTOR3,CNTN1,GLOD4,MIR30A,MIR21,RPL28,DSTN,RAB14,CD9,PSMA5,STX7,CNDP2,CD79B,RPL10A,HSP90B1,UBXN6,H2AJ,FTL,ATP5F1B,GPC1,PHB1,GFUS,VMO1,MIR143,ITM2B,NUDT5,CHP1,MIR31,SAT2,SERPINA1,SYPL1,RAP1A,TUBA1A,CYRIB,SYNGR2,XPNPEP1,PIP4K2C,PCBD1,F9,NHERF1,MIR1304,SMURF1,PABPC1L,RAB3B,PSMA3,RPL35A,CD274,SPTBN1,PROS1,RPS16,H2AZ1,PLA2G15,PRDX4,UBL3,MARS1,SDC4,GLRX,TNFSF10,BLVRA,CAND1,HSP90AB1,ACTR1B,FURIN,DDX5,PGK1,CD40,DDAH1,MIR221,GSTT1,HSPE1,EHD4,SDCBP,HSPA5,H2BC9,TSPO,PSMB2,MIR30B,IL18BP,UBA52,RBP5,PSMB3,CFL1,WASL,AHCYL1,SIAE,FGR,JUP,CD59,REG1A,RPS3,RPL23,GNA14,ALCAM,HP,HSPB1,FOLR1,SPR,ENPP4,MIR223,CLU,ACTN4,HNRNPA2B1,RPE,RAP2C,MIR214,GSTO1,MIRLET7I,CD2AP,MMP9,KIF3B,MAT2B,CRYL1,CRTC2,FSTL1,SCAMP2,RAB13,SEMG2,RACGAP1,ALDH1L1,H2AX,FBLN5,DICER1,CPNE1,GNG7,HEXA,MACROH2A1,UGDH,IDH2,ATP8A1,RAB3A,PSMA4,AGAP2,STXBP1,TPM3,H2AC1,SLC22A6,SERPINC1,SLC38A1,PLSCR1,RAB1B,GDI2,TAX1BP3,HTRA1,ITGB8,RPL22,SLPI,MIR671,ARF6,ACTB,SERPINB9,SEMA5A,PRSS23,DNM2,RP2,MIR145,ABHD8,YWHAZ,SLC22A8,ST3GAL1,RPS27A,MIR185,RAP2B,EMILIN1,SQSTM1,CLTRN,CD86,H2AC4,MTMR2,CCT8,UBB,PSMB6,DPP4,CTSA,MGP,P3H1,S100A10,CRABP2,GNB4,VTA1,SLC25A1,ALB,RPL24,CTSD,SLC11A2,COL1A2,CDH11,MIR422A,GPT,RPL4,PYGB,NAPG,RAB19,REG1B,RPS2,TOLLIP,SERPIND1,RAB8B,SRPRA,ACO1,SELENOP,CTDSP1,RALB,GNG5,CHMP1A,RPS11,H2AZ2,IDH1,HSP90AA1,DLG1,MYO6,NIBAN2,WASF3,GPM6A,PGM1,RHCG,F11R,GSTM2,PGA4,CD14,ARF4,GLUL,PRKCA,MYO1B,DAG1,RAB1A,MIRLET7D,RPL31,ACTR1A,STK24,RUVBL2,TNIK,NEU1,MIR342,SEPTIN7,B2M,ICAM1,GPRASP3,CRB3,PPFIA3,PLG,SPTAN1,CHMP1B,ATP6V1A,G6PD,CRYM,CHID1,RPL12,DNAJB9,GFPT1,UBE2V1,FAM20C,SLC2A1,CMPK1,SAMM50,MEST,ITGAV,PSMC5,TMEM59,FASLG,UBE2V2,ATP6V1D,BAX,MYL12B,GNAI3,MIR15A,NAPA,CXCR4,RARS1,GRID1,TOM1L1,PDE8A,MIR191,HEBP1,EEF1G,RAN,VWF,MIR197,LAMB2,CD47,CUTA,SLC35F6,CAPN1,MIR193A,HSPA13,ANP32B,CAPG,GNPDA1,H2AC6,CFL2,TNFAIP3,PRDX1,VPS28,ACTA2,UGP2,SLC22A12,MARCKSL1,PDIA6,MIR9-1,CTSB,GGH,ALYREF,WNT7A,YES1,LYZ,PPIC,GSTT2B,HNRNPL,RAB5C,CSTB,SFT2D2,ENO1,GHITM,SERPINA5,CHMP2A,HNRNPK,RHOBTB3,ARL15,UBE2N,CHCHD3,RAB35,RAB9A,PRKCB,GPC4,ENDOD1,SORD,PSMD12,RALA,ARF1,GNB1,ACSL4,PDCD5,AMY2B,LYPLA1,SLC20A2,MIR30D,DES,SLC1A1,ATP6V1G1,PADI2,NUDT9,PEG10,AKR1A1,LAMTOR1,PSMD7,GANAB,DDX23,LDHA,CRYZ,LAT2,SRC,RPS5,KLK3,PLD3,ABHD14B,CHMP2B,ALDH1A3,MAN1A2,MIRLET7B,SEC13,MIR23B,IL6ST,ATP1A1,ENPEP,TAX1BP1,CA2,RAB27A,CPNE2,FCN2,EHD1,MIR20A,RNF11,FBP2,HIRA,CYBRD1,B4GAT1,SLC15A2,RUSC2,CCT2,CCT5,FKBP4,RAB5A,NCSTN,ADGRG1,FAM168B,SOD3,SH3BP4,GNB3,RPL37A,RHOJ,OGN,LYPLA2,FAH,VAMP5,DEFB1,CCT7,MIF,GCNT3,UPK1A,SHMT1,BST2,HEXB,FLRT2,PRDX6,ATP1A2,MGAT4A,CEACAM5,PRRC2A,PPP1CB,GNG12,PSMB1,ATP1B1,ATP6V1C1,RPSA,H2AC7,LAMP2,TXNDC17,HINT1,MIR1234,PSME1,MIR126,SLC12A2,GSTM3,HBA1,PSME2,PTGDS,AQP2,PBLD,ITGB5,ANXA4,STAMBP,TFRC,GK2,IDE,NAA16,GSTO2,SRSF7,MIR30E,RPL27,GSTA1,ANGPTL2,MPST,GAPDH,ANGPT1,FGL2,GDPD3,BTG2,SFRP1,CD81,BPIFB1,PDIA3,DPEP1,LUM,MIR29A,SERPINA3,PACSIN3,PYGM,PAFAH1B2,DNAJC3,PRELP,ABCB1,GGCT,CDH13,ACTR2,RPS26,GBE1,LDHB,MIR222,RAB6A,RAB3D,CSK,MIR17,GNG2,SOD2,STK26,PRDX2,ATP5F1A,PCNA,DUSP26,HNRNPA1,PSMA2,RAB11B,SCPEP1,HSPD1,LAP3,CD58,S100A6,MIR152,RPS4X,GMPPA,FAM234A,LGALS3,BPIFA2,OLA1,CCL28,CPE,RPS13,THY1,TUBB,MIR24-1,RAB11A,RUVBL1,EEF1A1,NPC2,COMT,FUT8,SRI,PRNP,MIR619,MIR215,NEDD8,THRAP3,PABPC1,CAB39,ZNHIT6,SERPINB6,TCP1,PDZK1IP1,EPS8,GSTP1,MIR146A,PALS2,YWHAG,GSTA2,NCKAP1,OLFML3,C1GALT1C1,RAB29,AK2,ACP2,RAP1B,TOR3A,AKR1C1,MIR92B,PSMB4,MIR208A,PDCD10,USP14,HEBP2,ATP1B3,CSRP1,PEBP1,GCA,MIR106B,CRYAB,SFN,PNP,RPL26,ARPC2,TUFM,MIR106A,CTNND1,MIR29C,VAMP7,APEH,RPL3,TOR1B,PAFAH1B1,SLC16A1,TAGLN2,ARPC3,H2AC25,GNAI2,CFAP20,PLCB1,FABP5,AIF1L,SNX3,CYFIP2,MIR125A,HUWE1,PPIB,NME1,RHOG,BLOC1S5,MIR101-1,TF,CKB,NME2,RPS9,MBLAC2,CACYBP,TMBIM1,TNFSF13,KRT8,MIR23A,PEBP4,VPS4B,JCHAIN,GSTK1,PRKACB,RHEB,GLO1,RAB2A,CD248,STK11,SOD1,GALNT4,ACAT1,GSTCD,SERPINB1,ICAM3,ACTR3B,PITPNA,MIR423,TMED9,PRSS8,TUBB4B,MIR16-1,TXN,ADSS2,SNRPD2,UBE2D3,STOM,RPS14,CDC42,SLC2A3,GNAQ,SERPINI1,PSMA6,SNCG,VAMP8,MTAP,MIR638,CDK1,GPX3,RPS29,MIR194-1,RNASET2,GABRB2,ATP1A3,SVIP,RAB22A,NAA50,AKR7A2,YWHAB,AHSA1,LMAN1,AZGP1,EIF3E,AKR1B1,SLC25A3,VDAC1,S100A11,CHMP5,MIR26B,TMEM256,TIMP1,GMDS,PPT1,WWP1,HBB,CNP,FBP1,FTH1,LILRB4,AASDHPPT,IRF6,OXSR1,CD63,PRCP,ENO2,CLIC4,SSBP1,MBD5,RAB4A,CHI3L1,MIR198,MGAT1,CAPZA1,SNX18,BPGM,ST13,AP1M1,TOM1L2,PI15,MME,S100A8,CYB5R1,EIF2S1,PSMD3,TPT1,PPIA,CXCL12,F2,MIR192,ALPL,CAMP,PSMA1,GNPTG,MIR10B,EIF4E,RHOB,FAM3C,WWP2,RRAS2,SYT4,SPP1,CUL3,NECTIN2,CSE1L,MIR338,DDAH2,PLAA,CMBL,MIR130A,CALR,PROM1,RPLP0,SIT1,FAS,SEMA3C,PPP2R1A,CAPZA2,SH3BGRL,SNAP23,RPL26L1,TXNRD1,CTNNB1,ATP6AP2,HNRNPC,SNAPIN,GLIPR2,AP2M1,PSMB9,MIR34A,CSNK2B,ESD,HSPA8,MDH1,PPFIA2,IFT172,GPX4,ARHGAP1,MYL6,VPS4A,TTR,MIR148A,CD38,MIR100,PMP2,AOX1,RPLP2,RPL23A,CTSC,RAC2,TOM1,GOLGA7,H2BC14,MIRLET7C,ZMPSTE24,STAU1,PSMB5,H2AC13,GNA11,FABP4,DDT,MIR99A,H3C1,LCP1,DDR1,DNPH1,RPS20,TSPAN3,TSG101,KRT7,PGAM1,EPCAM,GAL3ST4,FLOT1,RNASE1,RPS28,B4GALT3,YWHAH |
| 7.649e-11 | -23.29 | GFM1 (G elongation factor mitochondrial 1) | protein interactions | 85476 | 310 | 140 | 19454 | 5460 |
MRPL13,TACO1,DLST,CCDC90B,PARL,NDUFAF4,ATP5F1B,MRPL23,MRPL16,AUH,MYC,MTG2,PYCR1,HNRNPAB,PMPCA,BOLA1,RIT1,MRPS25,HADHA,NGRN,ARG2,EXD2,MRPS7,NDUFS2,RER1,MRPL57,OXCT1,ADRB2,IDH3B,PRDX3,NDUFAF3,MRPL12,NDUFA5,MRPS18A,ATP5PO,YBEY,GATD3,PHB1,NDUFS8,PNPLA8,EGLN3,HNRNPL,MRPL9,NDUFV2,MTRF1,CLPX,PFDN5,STOML2,MRPS35,MRPS26,MRPL18,RHOG,HINT2,COX8A,MRPS11,HSPD1,PREPL,THNSL1,MRPS17,HNRNPDL,IMMP2L,SAR1B,KRAS,G3BP1,ETFA,KGD4,ATP5F1D,HSDL2,ETFB,NDUFA12,NDUFS6,PDHA1,MRPS28,ACAT1,MRPL53,MRPS21,MAGOHB,USP14,TUFM,NDUFAF2,PYCR2,OAT,MRPS16,TWNK,DLAT,RPA3,GRPEL1,BCL6,POLDIP2,MRPL20,NME4,PDHB,MRPL17,MRPL41,MRPL40,MRPL10,NDUFAB1,MTRES1,RPA2,MRPS34,QRSL1,MRPS9,SSBP1,AIFM1,SDHB,MGME1,COX4I1,DBT,ATP5PD,MALSU1,MRPS23,MRPL24,MRPL50,LYPLAL1,TPM3,GRSF1,MRPS18B,RPL23A,HSD17B10,MRPL52,ATP5PF,MRPS18C,MRPL22,FASTKD5,RIGI,PDE12,MRPS33,HSPE1,TRIM63,PPIF,HADH,BCS1L,ATP5PB,TP53,NDUFA2,MRPL47,MRPL11,MRPL49,MRPL51,NDUFS3 |
| 7.849e-11 | -23.27 | CCT8 (chaperonin containing TCP1 subunit 8) | protein interactions | 10694 | 507 | 209 | 19454 | 5460 |
FBXW4,PSMA3,CRY1,MCMBP,PPP2R2C,ARL6,FBXL4,ALKBH3,WDR77,PPP1CB,PPARG,ACTB,TUBB,RPL35,PRDX2,CUL2,CUL3,DCAF4,BRCA1,ILK,PFDN4,PFDN2,HSPD1,ARL5B,PCGF3,SAR1B,PCGF6,RAD21,RAF1,GFPT1,NGB,NME1,RPN1,EZH2,POLR2C,PPP2CB,TRAF3IP3,PHB1,FOLR1,ARL11,IGBP1,EGLN3,PRPF19,UBXN6,PSMD10,SKIC8,AHSA1,IDH3A,PRPF4,RPA3,SOD1,FLCN,IRF7,CCND1,ATG16L1,WDR83,FAXC,METTL14,STOM,RARS1,PDCL,TUBA1B,CTNNA1,CCNF,UBASH3B,PTEN,ZBTB18,PPM1M,ARMC6,COPE,NDN,PDCD5,VIRMA,CIAO1,USP14,STK24,CDC73,FAF1,HSD17B10,HAPSTR1,DNAAF10,HUWE1,RIGI,DUSP21,FBXO25,CCT5,ACTR2,PPP4C,EEF1AKMT3,EFNA3,AIFM1,PTPN1,PRNP,ZBTB2,CDK9,SUV39H1,HDAC6,EPOP,CRBN,FGR,DDX39B,DDX5,HDAC5,HSPA8,STAU1,UFL1,FBXO42,SEC62,PPT1,ADSS2,PIH1D1,EIF4B,SNRNP40,PSMD6,TAX1BP1,ESR2,PSMB6,KLHDC8A,PSMA4,APOBEC3B,MYC,FBXW11,PSMD14,CCT2,COP1,PABPC1,CCT8,CTTNBP2,CDK5,VDAC1,KRAS,PFDN1,ISG15,TUBA1A,SOX2,PDHA1,PLS3,TUBB4B,MOB3C,DUSP6,DYNC1I2,TCP1,CCT7,PFDN5,MAPK4,DCAF4L2,IFI16,DDRGK1,ACTR3B,AGR2,DCAF5,CBL,HCFC2,PML,BAP1,KDM1A,HDAC3,HSPA5,MARS1,WDR55,CFTR,TRIM68,WRAP53,RPA2,HECTD1,UBE2M,HEXIM1,PSMA6,UQCRC2,MOB4,MAP3K3,BUB3,KCTD9,SMURF1,CDC20,PTPN11,ETFBKMT,AKT1,MAT2A,SLC25A1,FGFR1OP2,RC3H2,RAP2C,UBE2H,ATP1A1,PSME1,METTL18,MAP1B,DYNC1I1,KDM4B,STRADB,CAPZA1,DUSP19,MEPCE,PHF1,TP53,RRM1,ACTR1A,TFCP2,FZR1,CDC5L,TMPO,KARS1,ELOC,CSNK2A1,COPS5,B9D1,TUBG1,MAP4 |
| 7.928e-11 | -23.26 | RPS14 (ribosomal protein S14) | protein interactions | 6208 | 475 | 198 | 19454 | 5460 |
SMAD2,CDC16,PPP1CC,USP14,RPL26,RPL13A,NDN,VIRMA,RPL22,METAP2,CCNF,RPS20,RPS12,PRKRA,GRM2,METTL14,RPL26L1,RPLP0,ZNF574,UBA52,CCNA2,CDK7,FBXW7,RPL4,HMGB1,PIAS1,SIRT7,RPA3,HDAC6,TOP1,RPL35A,NOP9,MDM2,RCHY1,KRR1,RPL12,SRP72,FBP1,RPL15,MAP1LC3B,AURKAIP1,EEF1A1,TAF1D,VRK1,FRMD8,NOC4L,HUWE1,RPS13,RPL23A,BRCA1,SENP8,RIT1,RPS5,CUL3,CUL2,ACO2,RPS29,AK3,RPL35,RPL7L1,RPL19,GGPS1,RPS9,SEC61B,RPL37A,H2AC1,MTX2,WDR77,H1-5,CDKN1A,G3BP2,RLIM,CCDC86,CRY1,PSMD10,RPL23,AHSA1,RPL7,NOP58,PHB1,RPL8,RPL9,FOLR1,HP1BP3,RPLP1,RPLP2,CHMP4C,EZH2,RPS11,B3GNT2,TRIM37,RBBP7,RAD21,SAR1B,TRIP4,RPS24,RC3H2,TRIM23,SPOP,UBE2H,PTTG1,CCNB1,RPL7A,RPF2,RPS17,RPL10L,CDC20,SMURF1,PSPC1,RPS3,SEC61A1,FGFBP1,RBMX2,PSMC5,RPA2,HEXIM1,UBE2M,CFTR,FGF13,RPS15,NLE1,RPL27,BAP1,RNF113A,SNRNP70,RPL24,TUBG1,RPL10A,TSNAX,MAP4,CDK12,TAF9,RPS2,COPS5,CD81,CSNK2A1,CAND1,RPS16,FZR1,RBM42,RPL32,DNAJC2,TFCP2,CERK,RPSA,TP53,UBL4A,KBTBD4,TMEM33,RPL17,MEPCE,SNIP1,DHX9,RPL3,ATG3,NSA2,RPS26,ICAM1,COP1,MYC,BTF3,PCMTD1,RPL10,SMU1,PIH1D1,EIF4B,PAFAH1B1,RPL27A,STAU1,UFL1,RPS28,SPECC1L,PYM1,HSPA8,AGR2,DCAF5,DRG1,RPL6,WWP2,CTNNB1,NGDN,DDRGK1,YWHAH,XPO1,NOB1,RPS10,EED,RAB4A,RPS23,RPL18,RPS7,SOX2,NCSTN,KRAS,RPS4X,RPL28,RPL31,RABGGTB |
| 7.951e-11 | -23.26 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | REACTOME pathways | R-HSA-975957 | 120 | 72 | 10285 | 3229 |
RPL35A,RPL24,RPL23A,RPL7A,RPL28,RPS14,RPSA,RPL6,RPS20,EIF4A3,RPS24,SMG5,RPS16,RPL3,RPL32,FAU,SMG9,RPS4X,RPLP1,RPS29,RPL13A,RPLP0,RPS13,RPL10L,RPL27A,RPS27A,MAGOHB,ETF1,RPLP2,RPL8,RPS5,NCBP2,RPL15,RPS26,RPS17,RPS28,RPL22,RPL17,RPS3,RPL26L1,PABPC1,RPL10,RPL35,MAGOH,RPL19,RPL12,RPL18,RPL9,RPL31,CASC3,RPS2,RPL27,RPS12,RPL4,RPS11,RPS23,PPP2R1A,RPL37A,RPL7,UBA52,RPS9,RPS15,RPL23,UPF3B,RPL29,RPL10A,RPL26,RPS7,RPS27L,SMG8,RPL39,RPS10 |
| 7.951e-11 | -23.26 | Nonsense-Mediated Decay (NMD) | REACTOME pathways | R-HSA-927802 | 120 | 72 | 10285 | 3229 |
RPL8,RPS5,RPLP2,MAGOHB,ETF1,RPS17,RPS28,NCBP2,RPS26,RPL15,RPL13A,RPS29,RPLP0,SMG9,RPLP1,RPS4X,RPL27A,RPS27A,RPS13,RPL10L,EIF4A3,RPS20,RPL6,RPSA,RPL3,FAU,RPL32,RPS24,RPS16,SMG5,RPL24,RPL35A,RPS14,RPL23A,RPL28,RPL7A,RPL29,UPF3B,RPL10A,RPL23,RPS15,RPL39,SMG8,RPS10,RPS7,RPL26,RPS27L,RPS11,RPS23,RPS12,RPL27,RPS2,RPL4,RPL7,UBA52,RPS9,RPL37A,PPP2R1A,RPL12,CASC3,RPL31,RPL9,RPL18,RPL17,RPS3,RPL22,MAGOH,RPL19,RPL26L1,RPL10,RPL35,PABPC1 |
| 7.979e-11 | -23.25 | PSMD11 (proteasome 26S subunit, non-ATPase 11) | protein interactions | 5717 | 338 | 150 | 19454 | 5460 |
PSMD10,DCAF11,BCL2L1,ATG9A,GSTM3,PSMD3,ATG7,DDRGK1,CCAR2,EGLN3,DHX15,HSP90AB1,PSME2,PSMB4,PSMB5,PPP2CB,ZHX1,COPS2,PLS3,KDELR1,CHMP4C,MOB3C,SOX2,ISG15,PPP2R1A,HNRNPF,PSMA2,ZBTB16,PSMA1,KRAS,PSMD12,RPS27A,UBE3A,BRCA1,PSMD14,CRMP1,RIT1,MYC,PSMA4,PRMT6,PSMD1,PSMD4,MTM1,DYNLL1,PSMD6,PSMB6,LRIF1,ESR2,LMBR1L,CCDC90B,SNRPD2,PRMT5,PPARG,PSMB7,MED31,PSMB3,PPP1CB,TMC7,UFL1,PTN,EEF1G,PSMC1,DDI1,RNF11,IGSF21,HSPA8,CRY1,HDAC5,STK26,PSMA3,SMAD4,CCDC92,PSMD7,USP15,MAP4,NFKB1,TLE1,COX5A,ZFAND2B,ELOC,GAPDH,ASB11,FZR1,PRNP,CDC5L,SMAD3,PSMB1,TMEM31,ZFAND2A,RAD23B,PSMC3,KBTBD4,INSIG2,TP53,EEF1A1,PSMB9,SMAD1,SEM1,PSMA5,HUWE1,TGFBR2,TOLLIP,MEPCE,FBXO25,VTA1,FKBP8,PTGES3,RAB1A,MAP1B,PSME1,GLUL,HAPSTR1,HSD17B10,NLRP9,SPOP,SMAD2,NAPA,ATP1A1,UBE2H,PSMB2,USP14,AR,ADRM1,VIRMA,SMAD5,CCSER2,PSMA6,PSMC5,RPA2,GRM2,HEXIM1,UBE2M,ACACA,PSMC4,SPTBN1,UBA52,CDC42,CFTR,PAAF1,UBLCP1,FBXW7,DESI1,EIF4E,HSPA5,SOD1,PRIM2,RPA3,DVL2,BAP1,DERL1 |
| 8.259e-11 | -23.22 | LRRK2 (leucine rich repeat kinase 2) | protein interactions | 120892 | 481 | 200 | 19454 | 5460 |
PRDX1,PIK3R1,PDIA3,RPL23,CETN3,RPLP2,PSMB5,RAB11B,STK3,CACYBP,ERLIN1,RBIS,PPP2R1A,E2F4,DPH5,ARFGAP1,EIF1AX,NME1,SKA3,ERP29,BAG2,HSPD1,ANP32B,AHCYL1,RAB11A,CFAP20,RIT1,SCFD1,HSP90AA1,BAX,LMNB1,YWHAZ,VGLL4,TUBB,RPL35,TSN,ACTB,PRDX2,SUPT4H1,PRDX3,TIMM13,MYL6,KCTD12,USP39,PSMA3,COIL,MCMBP,TGIF2LX,PAFAH1B2,MFN1,HDAC6,ATP5MG,CALR,UBXN10,PSMB1,MAP2K6,ACTA2,DFFA,SRP14,TOMM70,CXCL11,EEF1A1,PPIF,MAP2K3,MRPL11,ACTR2,HSD17B10,PPP1R12A,PRDX4,OLA1,CSK,MAPRE1,LRP6,CA2,LGALS8,STK24,MSN,GNPDA1,ENO1,STUB1,GNAI2,DEK,SNX3,TMOD3,MYL12B,TPT1,SF3A1,PDCL,HSP90B1,SQSTM1,ARPC2,CSTB,RPA3,DVL2,DAD1,YWHAH,PPIB,YWHAG,HSPB1,YWHAB,POU5F1,FKBP4,GSTO1,AK2,HSP90AB1,SUMO2,RAB1B,RPS10,H1-3,TRAF2,TUBA1A,RANBP1,CRKL,ZRANB2,PTRH2,PLS3,RUVBL2,MYO1B,RPAP3,CDK5,CCT8,PAK6,VDAC1,PSMA1,UFD1,BAG3,SNRPB,SFN,HNRNPAB,DNAJB6,MDH1,CRMP1,CKB,EFHD2,APEX2,VDAC2,DDIT4,CDC42EP3,PSMB6,PSMD6,SNRNP40,TAGLN2,PSMD4,NDUFAF3,RALYL,PSMB3,KLC2,RAB5A,HSPA8,RPS28,PEBP1,SRSF2,TPM3,PGAM1,USP15,MAP4,AKR1B1,UBE2N,ESD,MIF,RPSA,TP53,STRBP,RRM1,GNAI3,CAPZA2,CBX3,TCEA2,MAP1B,CAPZA1,MPST,CSE1L,TMEM33,H3C1,CFL1,SUB1,PSMB2,AKT1,SMARCA5,BICD2,STN1,TRIM23,GLOD4,PITPNB,PSMA6,SUCLG2,ADRM1,DAPK1,NTPCR,WSB1,CDC42,AGO1,PPP1R8,DYRK2,GSTP1,TXNDC17,RAB29,HSPA5,GRPEL1,RPS15 |
| 8.410e-11 | -23.20 | UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1) | protein interactions | 7311 | 341 | 151 | 19454 | 5460 |
B3GNT2,NUP37,RPS7,VAMP2,ZRANB2,HGS,TMT1A,HNRNPA2B1,PCNA,FAM168A,UFM1,PSMA1,KRAS,VDAC1,UBE2A,RPS4X,PSMD12,RPS27A,FLOT1,RAD21,AHCYL1,IFI16,PDIA3,RAB5C,NCK1,CBL,RAB35,MT1M,TSG101,GJA1,USP46,RPLP2,CCAR2,HSP90AB1,RPL27A,NOTCH2,PLSCR4,SLU7,WBP2,HERC3,ARRDC3,PXMP2,RNF11,STX7,PSMC1,MYC,APOBEC3B,GRB10,HMGCS1,LAMTOR1,RHOB,PSMD14,HSP90AA1,CRMP1,RPS5,RIT1,SERPINH1,MDH1,VDAC2,APOBEC3G,RSRC1,DKK3,SEC61B,PSMD4,TAX1BP1,RPL35,UBL4A,MTCH2,TP53,SMAD1,UBE2B,ACVR1,TBC1D4,FAF1,PPP1R12A,NEDD8,PSMA5,HUWE1,MEPCE,PRDX4,RPL17,BMPR1B,DNAJB2,GAPDH,SMAD4,H2AC4,RPL24,RPS2,EMX2,AIFM1,RPL32,NLRP1,HSD17B11,CD4,RPL35A,ARF6,EIF2B2,MDM2,KLK3,CAV1,RPS14,UBA52,DENND2D,CFTR,CDK7,HEXIM1,HECTD1,DVL2,CYP17A1,PML,PRKCB,RNF113A,SQSTM1,UBE2K,LITAF,RPL4,DESI1,VPS28,HSPA5,AKT1,RAB2A,PSMB2,CCNB1,CIAO1,SUB1,H2BC9,ATP5F1A,FBXO7,CFL1,SPOP,CHCHD4,TXNIP,DCAF16,SMAD2,CDC73,OAT,CCNF,STUB1,RPS3,PSMA6,TUBA1B,CYTH1,PSMC5,EIF2S2,MSN,RPS20,NDN,MAP3K3,ADRM1,UBB,SMURF1 |
| 8.512e-11 | -23.19 | large ribosomal subunit | cellular component | GO:0015934 | 111 | 65 | 19108 | 5553 |
RPLP1,MRPL18,RPL39,MRPL40,RPL19,MRPL22,RPL9,MRPS18A,RPL26L1,MRPL51,MRPL24,MRPL57,MRPL50,RPL31,RPL10L,UBA52,MRPL52,RPL35,MRPL33,MRPL47,RPL37A,MPV17L2,RPL32,RPL27,ZCCHC17,MRPL41,MRPL11,MRPL20,RPL17,MRPL9,MRPL34,MRPL49,RPL24,RPL26,RPL7L1,RPL23,RPL35A,MRPL53,RPL28,RBM3,RPL7,RPL23A,RPLP2,MRPL17,RPL13A,MRPL12,MRPL23,MRPL36,RPL29,RPL8,RPL6,RPL10,RPLP0,MRPL16,RPL18,MRPL10,RPL3,RPL27A,RPL4,RPL15,RPL12,MRPL13,RPL7A,RPL10A,RPL22 |
| 8.616e-11 | -23.17 | macromolecule catabolic process | biological process | GO:0009057 | 962 | 374 | 18204 | 5365 |
DERL1,PSMA3,GSK3A,PPP1R8,PSMD7,SYVN1,PCSK9,TSG101,FBXL19,UBE2N,UBE2D1,TRIM24,PSMC3,SKP1,PLAA,PSMB3,SPSB1,SEC61B,TOLLIP,XBP1,GID8,HYAL2,CTSK,TNFAIP3,CTNNB1,ARMC8,PSMA4,CALR,PSMD6,SKIC8,PSMA5,GRSF1,PSMD12,WDR77,FBXO9,UBE2W,CNOT2,FEM1C,PPP1R11,MAGOH,RNF103,SNX5,GPC1,UBXN6,ISG20,SELENOS,DDI1,RPS27A,EXOSC8,UBA52,LSM4,DNASE1L1,RNF128,SIAH2,AKT1,RNASEH2C,UBE2G2,HERC4,DXO,TP53INP2,CHMP2B,EXOSC1,BAP1,PMAIP1,PSMB6,IFI27,CHMP2A,MMP20,DNAJC3,DNAJB2,JKAMP,PSMB2,UBE2S,ECRG4,WDR82,ANAPC2,HM13,UBE2B,RHOBTB3,MAEA,PSMB11,SMG8,SMURF1,PSMB7,CHMP1A,UBB,LSM5,LAMP2,TOM1L1,USP38,HEXA,UBE3A,RNF14,ERLIN2,RNASE6,UBE2K,MAGEC2,THRAP3,KLHL25,PELI1,TENT4A,LDLR,OVGP1,PSMA6,PPP2CB,RNF122,HECTD3,PABPC1,UBXN2B,RNASET2,RMND5B,PML,MRTO4,PSMC5,DISC1,CHI3L1,CLPX,FBXW4,RNF40,RNF26,RNF10,VPS54,USE1,NAE1,CCNF,MYLIP,CD2AP,NUDT12,BIRC2,CNOT6L,PSMC4,KBTBD6,ELOC,PNRC1,EIF4A3,HNRNPD,TRIM32,UBE2L3,KCTD10,UBAP1,PSMA1,RNASEH1,HDAC6,FBXW7,ANAPC13,UBL4A,DERL2,BFAR,PSMC1,CLU,EXOSC3,SPSB3,CCAR1,LYPLA1,RNF115,EDC3,BNIP3L,TMEM199,NUDT16,EIF3E,FBXO7,NFE2L2,FBXO44,METTL14,AREL1,CAPN2,RNF148,MAN1A2,TRIM3,PSMD1,KLF1,CUL3,CCDC47,ZNRF1,ZFAND2B,MAGOHB,ADRM1,LYPLA2,CACUL1,TRIM45,APEX1,RNF121,CDC23,RNF146,DTL,SPOPL,TENT2,FBXL3,RNF41,POLR2G,SQSTM1,TRIM21,ANKIB1,UTP25,PSMB4,RB1CC1,EXT1,RNF126,HGS,CTSB,ANAPC11,OS9,PRPF19,PELO,EDEM1,USP14,PGPEP1,UBXN10,CNOT6,DNAJB9,PYM1,PSMB1,DICER1,TOPORS,BECN1,ZCCHC7,NDFIP1,CBL,BAG3,FEN1,EXOSC4,OTUD7B,LSM2,FBXL4,RNF11,KLHL15,NEDD8,ZFAND2A,RLIM,DCAF11,STBD1,UCHL3,TMUB2,RBM7,RNF167,RNF8,ISG15,FAM8A1,VPS4B,FEM1B,SDF2L1,DBR1,LYPLAL1,KCTD17,ANAPC15,CMA1,ERLIN1,RNF7,RC3H2,SMG5,MTM1,PSEN1,TRIM26,IDE,UBE2I,WWP1,SPOP,PSMB10,ZMPSTE24,HSPA5,KLHL3,HTRA2,AGO1,FZR1,ABHD10,FAF2,CDC20,ANAPC4,RCHY1,FBXO11,ZER1,WWP2,CDC16,UBE2A,FBXO8,RNF34,WDR45,HSP90AA1,HERC3,SLC6A7,TNFAIP1,FBXW11,ATG3,SH3GLB1,HSP90B1,CAPN1,FBXO3,PYGB,RNF133,PSMD14,CTSD,TRIR,EDEM2,CASC3,RAD23B,RNF144B,DIS3L,ERLEC1,TMEM106B,PDE12,ETF1,PSMA2,FBXO31,TRAF2,PPT1,TMUB1,GID4,APPBP2,PSMD3,HECW1,RNF5,NSFL1C,CDK5,SH3BGRL,VPS28,DNAJC10,FEM1A,STUB1,MME,DFFA,ABHD17A,PSMD4,PCYOX1L,HEXB,UPF3B,FBXO22,YTHDF2,PSMB9,EDEM3,GABARAPL1,FAF1,SIAH1,CNOT7,RBCK1,UBE2H,CLN8,CUL2,RNF139,LSM6,SGTA,CSNK1A1,LYG2,CHMP4C,LIPA,CHMP5,RNF187,COP1,DCP2,RNF20,NQO1,HECTD1,UFD1,KLHL22,ANAPC16,UBE2D3,VPS4A,NCBP2,DDX5,FBXL14,CTSC,PSMB5,PYGM,MDM2,CDC26,DDIT3,FBXL7,HUWE1,CRBN,ENC1,SMG9,HSPA8,CHMP1B,TRIP4,CNOT8 |
| 8.844e-11 | -23.15 | PSMA5 (proteasome 20S subunit alpha 5) | protein interactions | 5686 | 330 | 147 | 19454 | 5460 |
EDC3,SLITRK5,PSMG2,PSMD7,PTPN1,MRPS9,PSMB1,CAND1,FZR1,PRNP,MAPRE2,PSMB9,CAMK1,RNF8,RAD23B,PSMC3,MAP1B,CCR5,PSME1,ABCE1,DHX9,SEM1,NEDD8,PSMA5,HUWE1,MEPCE,PSMB10,PSEN1,FKBP8,CAPZA1,PSMB2,CDC16,FBXO7,USP14,MRPS16,TXNIP,STK24,TRIM23,ANAPC4,PSMG3,UBE2H,CCNF,PSMA6,GANAB,MOB4,PSMC5,ADRM1,UBE2L3,SH3BGRL,SMURF1,VIRMA,SF3A1,PSMC4,UBA52,PAAF1,CFTR,XBP1,CDK7,CDK1,QRSL1,GRM2,UBE2M,ACACA,WTAP,BAP1,IRF3,SYVN1,EXOSC4,PSMG4,FBXW7,DESI1,TMEM209,PSMD3,CTNNB1,DDRGK1,SKIC8,DDX23,PSMD10,AGR2,RB1CC1,CDC23,PSME2,PSMB4,PSMB5,TYMS,SNRPA1,DYNC1I2,SLMAP,EGLN3,DHX15,RAF1,B3GNT2,SUPT5H,TRAF2,SOX2,ISG15,KIF2A,EZH2,POLR2C,MTA2,SART3,MOB3C,HGS,HNRNPA2B1,UBE3A,PSMA2,RBBP7,PSMA1,KRAS,PSMD12,MYC,CUL3,PSMA4,CUL2,LDB1,PSMD1,BAG3,POMP,FAS,BRCA1,YWHAZ,PSMD14,RIT1,SRXN1,FOXP3,TAGLN2,PSMD4,PSMD6,PSMB6,POLR2B,USP5,ESR2,CLIC4,PSMB3,PSMB7,DDX39B,HSPA8,HDAC5,PSMA3,SRSF2,COIL,SAP18,PSMC1,DDI1,UNC45A,MRPS7,SKP1 |
| 8.975e-11 | -23.13 | SND1 (staphylococcal nuclease and tudor domain containing 1) | protein interactions | 27044 | 283 | 130 | 19454 | 5460 |
EP300,HADHA,HSPA8,G3BP2,STAU1,SSR3,UFL1,MRPL12,SEC62,TOMM22,PIH1D1,LARP4B,RPS9,SEC61B,DLST,VDAC2,LMBR1L,RPL19,RPL10,ESR2,SNRPB2,RPL35,PDE4B,CUL3,HNRNPC,MYC,CREBBP,HSP90AA1,RPS26,BRCA1,FAS,RPS24,TMT1A,G3BP1,GTF2E2,DNAJC25,ISG15,MAX,ARFGAP1,TOP3B,STX12,RPS11,RBPJ,SMNDC1,PDHA1,STIM1,EZH2,RPN1,PLS3,SPINT2,GJA1,CORO1C,HSP90AB1,CCT7,SUMO2,CTNNB1,ZNF207,DDRGK1,WWP2,IFI16,PDIA3,AGR2,MTDH,DLAT,SQSTM1,GFM1,SIRT7,RPA3,SOD1,BAP1,AATF,RPL4,EIF5B,MYL12B,SF3A1,ATG16L1,STAT6,HEXIM1,MMP28,WWP1,SSR1,IDH2,METTL14,FGFR1,RPA2,UBE2I,RPS20,CCNF,RPS3,PSPC1,VIRMA,SEC63,SMURF1,TXNDC12,NDN,DNAJC8,UBE2H,MAPRE1,ATP1A1,DHX9,IGF1R,RPL23A,FKBP8,SEM1,HUWE1,MAP1LC3B,H2AX,TP53,ATP5PB,NUPR1,PSMC3,ILF2,MYBL2,RCHY1,UBE2N,PTPN1,CD274,SYNCRIP,MDM2,TMPO,RPS16,DNAJC1,CAND1,FZR1,GTF2E1,CSNK2A1,EMC4,RPS2,PTGER4,SNRNP70 |
| 8.981e-11 | -23.13 | intracellular protein transport | biological process | GO:0006886 | 556 | 234 | 18204 | 5365 |
TRAM2,IFT22,HSPA5,FAM53C,TNPO3,SMURF1,TIMM17A,AP2A1,CACNG3,EGR2,PPP1R10,HM13,SFN,PEX5L,TIMM29,TXNIP,XPOT,VTI1B,AP2M1,SNAPIN,VPS18,RAB1A,AP1S2,TMED1,AP1G2,TNPO2,YWHAH,VPS26B,RAB18,VPS33A,NXT1,MTCH2,STK3,CLIP3,SYNDIG1,STX8,HSP90AA1,SEC61G,ARL11,KPNA1,DNAJC19,MYO6,RAB23,DNAJC27,SLU7,FAF2,HSPB1,ERP29,TOMM40,TRAF3IP2,ARFIP1,LAMP2,AHCYL1,BAG3,ARL5B,TIMM8A,SEC61B,CCHCR1,SYNRG,BECN1,NUP153,NUP50,NAPA,ATP1B1,POLA2,STX7,XPO5,OS9,COPZ2,STXBP1,CSE1L,TSG101,BCAP29,DERL1,WDR11,VIPAS39,TUBA1A,RABL2B,RAMP3,FAM91A1,SYVN1,KPNA6,RAB28,HGS,RAB1B,AKT1,EIF2D,RABL3,PEX13,NAPG,TRIM37,LMNA,TOMM22,PEX26,FAM53B,PPP3CA,VPS39,SELENOS,SNX33,TMED4,VPS26A,TIMM10,CHP1,CALR,NSG1,NFKBIA,SNX5,ROMO1,RAB5C,AP1M1,VPS26C,RAB29,STX12,MTX2,UFD1,PIK3R1,RAN,TMED5,AGK,SNX1,SNX11,RPL23,TMED3,DESI1,TIMM21,SCFD1,AP3S2,TOMM7,ARCN1,STX17,AP2S1,SNX2,SAMM50,SEC62,SRP54,KPNA2,SNX17,RAB32,IPO8,CTSA,SEC61A2,TOMM6,LARGE1,HSPA8,TRAM1,ARF4,NUP42,STX18,SQSTM1,NETO1,HIKESHI,TOMM70,RPAIN,PHB2,TMED7,STK4,ARF1,TP53,RAB22A,SNX10,NUP107,GNPTG,SEC23A,ARFGAP3,STX5,VPS4A,ZFAND2B,EHD1,RAB8B,STX10,ARL4A,SURF4,GPIHBP1,RAB5A,VPS16,NDP,SEC61A1,LMAN1,STX6,RAB19,ARF6,PICK1,TRMT10B,VPS54,ARL6,NUP62,HSP90B1,PML,SRPRA,CDKN1A,TRAM1L1,TIMM23,TOMM20,PEX3,TBC1D13,SPRN,CTTN,TRIM23,NUP35,TIMM8B,STRADB,DRD1,RAB31,ARL4D,SCG5,VPS28,DERL2,CTDSPL2,RAB6A,STX1A,CDK5,RAB14,CLU,SYK,RANGRF,GRPEL1,STX11,TMED9,STX16,RHOB,HDAC6,XPO1,RANBP6,APPBP2,UBAP1,GRPEL2,SEC63,RAB6B,ERLEC1,ING1,RAB11A,TIMM13,SEC13,RILPL2 |
| 9.045e-11 | -23.13 | NUDCD2 (NudC domain containing 2) | protein interactions | 134492 | 415 | 177 | 19454 | 5460 |
TFRC,SURF4,ARPC3,ACTR1A,ZMYM3,PDRG1,CAPZA1,H3C1,HNRNPK,KPNA2,RPL3,DHX9,PALM2AKAP2,RPL24,GAPDH,MYL12A,LMAN1,RPS16,EEF1B2,SYNCRIP,SSBP1,MRPS9,ALYREF,RPA2,SSR1,PLP2,SPTBN1,HSPA5,RNASE1,PRDX6,ATP1A1,UBE2H,SORD,CDKN2AIP,CFL1,RPL7A,CSTF3,UBA3,BCCIP,RCBTB1,KLK6,RPS3,SF3B6,RPL18,PLS3,RPS7,PPIL3,HNRNPDL,MYO1B,CTTNBP2,RPL31,PABPC1,YWHAB,RPL6,CCT7,HNRNPL,SNRPA1,CORO1C,SRSF1,EIF4B,RPL27A,EFHD1,PAFAH1B1,SAP18,TRA2B,SRSF2,HNRNPA0,EEF1G,SSR3,SF3B1,HSPA8,SNRPA,HERC3,XRCC5,RPS28,PRSS1,PSMD14,H1-10,SNRPB,OST4,HNRNPC,HNRNPAB,ATP5F1B,TAGLN2,SNRNP40,PRMT5,ILF2,MRPL49,GINS4,ACTR2,EEF1A1,RPL15,CCT5,EIF3E,H2AC6,PTGES3,THRAP3,RPL23A,PC,HSD17B10,PPP1R12A,RAB1A,GRSF1,NFKB1,SLC25A12,PPP1R18,PRNP,SSU72,RPL12,ACTA2,RPLP0,RPL26L1,LMNA,SLC12A2,RPS14,SF3A1,UBA52,SMC4,RPL4,RPA3,ATP5F1A,NONO,RPL22,VIRMA,COPE,LDHA,TMOD3,RPL13A,RPS20,STUB1,TUBA1B,CTTN,EZH2,ACTN4,RPL29,G3BP1,RPS24,SLC25A5,HSPD1,HNRNPA2B1,HNRNPD,RPL23,HNRNPA1,EIF3D,ZNF593,OS9,DHX15,NOP58,SPTAN1,RPL7,IGBP1,RPLP2,RPLP1,RPL9,RPL8,MYL6,PSMB7,DET1,H1-5,WDR77,G3BP2,TTC1,RPS5,HSP90AA1,NOA1,YWHAZ,LMNB1,DCAF4,ERH,RPL19,ACTB,TAB1,RPL35,SNRPD1,SNRPD2,RPS9,EIF3K |
| 9.087e-11 | -23.12 | CAV1 (caveolin 1) | protein interactions | 857 | 719 | 280 | 19454 | 5460 |
RAB4A,PTRH2,RND3,HGS,MOB3C,ADCY3,ETFB,ISG15,TRAF2,LPAR6,GJB1,KRAS,EPHA4,VDAC1,VAMP8,PRPS1,TMEM87A,EFNB1,HSPB1,LAMP2,WWP2,RAB5C,PPFIBP1,CTNNB1,SUMO3,RHOH,SUMO2,TNIK,RAB35,STX5,C2CD4C,PLAA,MMP14,AKR1A1,CAV2,USP6NL,YIPF5,TOM1L2,GOSR1,EMC1,PHB2,ITGAV,ABCC5,BMPR1A,CD40,RAB5A,AKAP1,LAMTOR1,GCC1,PSMD14,SLC38A1,KCNA3,SERPINH1,COX6B1,MYC,SLC1A3,UFD1,TOM1L1,ESR2,VDAC2,FAM83B,PIK3CA,TFRC,ZNRF1,EXOC3,BMPR2,CAPN2,GNAI3,NUPR1,SNAP29,CHRM3,TMSB10,AKAP12,TGFBR2,RAB3B,TOLLIP,SLC6A8,PALM2AKAP2,ATP2B4,MLC1,SELENOS,CSNK2A1,VTI1B,ESD,SLC38A2,STX6,LMAN1,ITGA6,UBE2N,SLC39A10,ADD1,MCL1,RAC2,MTAP,P2RY12,RPA2,CSNK1G3,SPTBN1,CAPN1,IGFBP3,CDC42,CFTR,STK38,SLC25A51,PML,ITM2B,PGK1,RAB9A,DERL1,STOML3,ENDOD1,KCNMA1,ATP1A1,SORD,UBE2H,NDUFAF2,SLC25A1,RAB2A,FGFR1OP2,GJB2,PTPN11,ARHGAP21,GORASP2,DNAJC5,HTR1F,TXNDC12,SRC,NECTIN2,VAMP2,AQP3,STX12,PLD3,MARCKSL1,E2F4,PPP2R1A,YIPF3,FAF2,IFNGR1,TULP3,RCVRN,TNF,TRIM37,PSMD12,AHCYL1,SAR1B,FLOT1,TMT1A,PRPSAP1,BAG2,RHOG,TRAF6,NQO1,PIK3R1,PDIA3,UBXN6,P2RY10,SPTAN1,DIRAS3,WDR6,PHB1,NEO1,GJA1,MAP1LC3A,KRT8,ABCB1,PPARG,VAV2,ARCN1,NOTCH2,RND2,EHD1,STX7,CXCR4,TACR1,BET1L,FAS,MYO6,RHOB,HSP90AA1,SLC7A11,SCFD1,FAM219A,ILK,NIBAN2,RAB11A,PKP4,CUL3,CAV3,JPT1,MB21D2,ACTB,DYNLL1,REEP4,USP5,GLIPR2,CYB5R3,LRRC1,ZDHHC8,CASK,CMPK1,SLC29A1,THRAP3,PDE2A,OLA1,CTNND1,ADD2,TLR4,GARRE1,DLG1,IGF1R,SNAP23,TRPC1,ESYT1,TIAM1,ID1,RELL1,MOV10,HDAC6,LAMP3,DAG1,RAB23,ARF6,PRNP,CDK9,G6PD,CAV1,HRAS,ALDH1A3,PTPN1,EHBP1,CDCA3,JUP,LMNA,SLC12A2,STOM,GOLGA5,MET,RABL3,ATG16L1,TPT1,PIP5K1A,ARHGAP1,UBA52,CNP,NF2,YKT6,PIK3R2,FBXW7,CDC42EP4,SLC5A6,RHOU,RPA3,PPM1G,SQSTM1,ITGA2,IVNS1ABP,ARFGAP3,SMAD2,LRP6,EPHA2,CSK,FLRT3,DEPDC1B,AR,RHOJ,YES1,SNX3,FERMT2,SH3BP4,GNAI2,VIRMA,VAMP3,GAB1,TMSB4X,CTNNA1,TNFRSF1B,CHRM5,GSK3A,MSN,PTEN |
| 9.099e-11 | -23.12 | lung-carcinoma | COSMIC cancer mutations | lung-carcinoma | 4255 | 1387 | 16828 | 4835 |
POLA2,POLB,EIF1AX,HSPD1,CCNH,PIAS1,PNPLA4,TCEA2,SAP18,SPSB3,DDR1,RNF148,PPP1R1A,MSTN,PIGA,BTG3,GADD45A,GRPR,VAV2,ITGB8,BTG2,GNB3,HINFP,TNKS,SLC22A17,PLS3,TRIM44,PPP2R2C,STK4,PIP4K2C,STUB1,NKIRAS2,ACVR1C,PQBP1,GPRASP2,SNRK,WDR45,GNA11,HSPA5,SERPINB1,SRSF2,HSPB6,RPL10,FBXW4,P2RY4,HLF,SERPINC1,RFC3,GPM6B,IP6K1,FBXO22,RNF34,PPP1R11,KLF4,COPS7B,DENND2D,MSH6,RAP2A,NCAPG2,ETF1,RNF10,POLE3,NFKBIA,TNFSF8,PLAC1,SIN3A,CDK7,TCEAL1,FKBPL,RAB6A,USP16,RGN,CD40,TNFSF15,ARFGEF1,TLR8,TP53INP1,TRAF3IP3,FAF1,SRPK2,TAB2,CCR1,DTWD1,ASTN1,RPA2,FBXL4,PTPN11,NOTCH2,EDA2R,FKBP1B,LMO2,FAM177A1,PSEN1,MCM4,MAGEC2,ORC6,DROSHA,STARD4,THOC2,ARHGAP12,UBP1,DIRAS2,IGF1R,CX3CR1,SS18,RUNX1,GJC1,SCML1,UMPS,TYMS,BIRC2,MTM1,SUCLG2,DUSP3,FCGR2B,SIAH2,CER1,TRAF6,ELF5,ROCK2,KRIT1,TKTL1,SCML2,DNAJC19,MYBL2,PLEKHO1,ERAS,SPRY1,CNOT2,FEN1,IMPA2,TRAM1,TADA3,FUNDC1,ASB7,PRKACB,MGMT,MDC1,SP1,SLC25A5,NLRP9,WSB1,TOPORS,LYZ,LAMP2,AR,ADCK1,TPM3,SNRPB,PTP4A2,FAM3C,PTPN4,RIT1,MAP2K1,PLCB2,APOBEC3F,CYTH4,STAT5A,TRIM26,COPS5,EIF4A2,OTX2,MAGEH1,FEZ1,EP300,ADAMTS10,UBE2G2,RNF8,PEA15,FXN,UPRT,PPP3R2,TIMP3,GMPS,CCR7,TTL,RRAGB,RASL12,SMAD1,GABPA,FKBP8,PPP2CB,RPL23,SPIN3,VAMP7,CTTN,GNGT2,NKAP,RABGGTB,FBXO7,DMPK,USP3,CDC23,TANK,TNFRSF1B,MPG,TGFBR2,TNF,SERPINA1,SUMO2,CCR4,KLF3,DAAM1,SESTD1,PPP2R5E,SH2D1A,FOXA3,PARP2,NF2,HSPA13,FBXL14,RHEB,GRAP2,RAB27A,COX6B2,RNF133,PRKCE,TSPAN17,DPH3,ELK3,CD81,UBE2E2,RPS6KA4,RHOBTB3,DDX46,OCRL,TBC1D25,IRAK4,WDR11,NHEJ1,IL2,NBN,CDC20,SNX22,XRCC5,TIMP4,GNAO1,CBLL1,RBBP8,UBA3,SGMS1,TRIM45,SRSF7,DUSP21,SAV1,STAT2,ST6GAL1,CDC7,FBXO8,BAG3,OXSR1,ORC5,DLST,RRM1,RBM22,KRAS,BCL6,HERC4,DKK1,SNX10,ZMYM3,USP6NL,HSD17B10,IER2,PPP1R1B,RND2,BCL9,BMPR2,NLRP3,CBX3,RASD1,BAX,CRTC2,COX6C,PICALM,NUF2,DAPK3,RAPGEF5,COCH,TMEM47,FBXL19,AP1S2,APEX2,SF3B1,CHIC2,PIK3CA,CDH11,TMEM185A,EPHA4,CITED1,ARL4D,PSMD10,TNNI3K,CDK12,FBXW7,USP15,SPP1,NTRK2,GNG12,APOBEC3G,TSR2,PLCB1,DNAJB9,RNF144B,GNAZ,YWHAZ,ICAM2,TNR,BOK,MAGED2,RLIM,PTEN,SURF2,UAP1,CCNA2,MAGEB10,CXCR3,SDHB,PCGF6,CCDC160,CXCL13,CKS2,RORB,RGL2,PPFIA2,ITGB5,TRIM34,NINJ1,FBXW11,BCL7C,TCEAL8,UBE2L3,PMAIP1,PGRMC1,RAB39B,CSNK1G3,COX8A,HUWE1,CPLX2,USP8,PTK7,FTSJ1,DHX38,NXT2,HSPB2,STK3,TNKS2,DCAF12L2,FZD3,RHOBTB1,PTP4A3,DDX23,PCNA,PIK3R2,SPRED2,NT5DC1,TRIM36,JAK2,NDUFS6,MCL1,PLD3,NDUFA1,DKC1,ZBED1,FBXO44,TRIM29,PNMA3,SERPIND1,CHST7,ORAI2,TNIK,ENO1,UBE3A,ZC4H2,CETN2,CBFB,RGS6,SMARCE1,TFPT,RIT2,ALOX5AP,PRDX4,SLC25A14,NUP35,MECP2,STYK1,MAP2K3,DOK5,CXXC1,FGR,SPHK2,RCHY1,ARF6,FBXL7,LBR,MAP3K3,EZH1,CAPG,RNF7,SAR1B,CCR5,ZBTB16,BRMS1L,UBE2I,MFAP1,MXD1,HCST,FBXO34,FTHL17,RALA,G6PD,ADK,MID1IP1,SYBU,SERPINB6,PTGES,MAGEB1,RNF128,DICER1,PPP2R5A,TLR7,SAP30,MSN,FGF16,POU5F1,FOXD3,FBLN5,TRIM35,PPM1B,CXCL10,SENP8,GPC4,SMUG1,KIN,ASCC1,TP53,DUSP18,KPNA6,TOX,COX7B,ASB11,RGS1,SDHC,RHOG,FAM83A,DUSP6,PDCD5,HMGB1,ARF1,GNG11,SERTAD1,ARF4,PML,DNASE1L1,ADAMTS20,HDAC11,DUSP22,PLCL1,DIRAS3,YWHAH,DNAJC7,PCYT1B,GJB1,SKP1,LCP1,RBM41,PRKCB,HMGA1,PABPC5,FOXI3,RGL1,SUV39H1,CKS1B,AUH,TFRC,WNT10B,FOXC2,RAB32,PITPNA,FBXO11,MLH3,PCBP4,SPSB1,APOBEC3B,RBBP9,BMPR1B,TULP3,MPP1,RANBP10,SUPT4H1,VPS39,ZNF189,PTPRZ1,EEF1B2,ZNF22,TFDP2,ATP6V1D,CDKN2D,BCL2A1,CDK17,APPBP2,IL7,TNPO2,SRSF4,SH3BGRL,RAB9A,FGF3,PLP2,SMG5,NUP62,NDP,RNF139,USP13,CMTM7,NEURL2,CCND3,ARL6,RAB11B,SNX12,IRF4,DDIT4,SMYD3,STK38L,PIGC,RAB3A,CTNND1,KPNA2,SHC3,CDC26,DDIT3,TCEA1,BCAS4,CHN2,VCPIP1,FOXJ3,USP30,JUNB,RAD23B,SMAD9,PTPN5,XBP1,COX6A2,MAD2L2,RBBP4,GPR34,FAS,ATF1,ERCC3,CUL3,ARHGAP19,NAP1L3,ARMCX3,DNAJC4,AKT3,POLD4,BCKDK,GRB10,CSNK1E,CHMP2B,PAK6,RBM3,HDAC3,GLRA2,RACGAP1,CORO1C,MAGEA4,LRRC4B,PIK3CG,COX4I1,ANAPC4,ARHGAP15,RHOH,UBE2S,ACVR1B,TIMM8A,EGR1,RAD21,AKAP17A,RAP1B,DNAJB4,SNX14,AIFM1,HNRNPH2,CLIC4,ANKRD10,ALDH1A3,ADM2,RPL39,BRD3,TESK1,DVL2,AMELX,RAB1A,GLO1,PRKCA,PDCD1LG2,FBXO31,PIGK,EEF1A1,GAS2,RNF5,FKBP1A,APEX1,GAB1,AKT2,RFC4,COTL1,TRIM6,SLC4A10,FOXP1,MMP20,ENC1,PLCXD3,SMARCB1,PDCD10,VAPB,GPR173,PRPS1,TOP2B,BAD,GEMIN8,TRAF1,RASSF4,SERPINA3,CLK1,RAB35,BRS3,PPP1R8,ZMAT3,PTGER2,MYC,CD40LG,HERC3,SNX1,PSEN2,STRADB,SIAH1,NCK1,IL2RG,CDC42,AHSA1,PLEKHF1,DUSP10,TRIM62,SYK,ACO2,COX7B2,CDKN1B,HMGN4,NLGN1,PSMA6,AKAP1,SERPINB9,UBE2V1,S1PR4,SNX11,PPP1R3C,CRADD,HELT,MET,FZD6,ATF3,RANBP1,ACSS2,DNAJC2,GNB1L,WDR82,DLG3,RHOU,RNF11,CYTH2,RPL22,UBE2H,CAMKV,ARL5B,PNMA5,ENO2,PSENEN,LDB1,SFRP1,ELF1,BIRC5,FGF23,RANBP6,TP53I3,SNRPA1,ABHD2,CCDC22,RNF40,KDM1A,DDX1,FKBP2,GMNN,RALB,ARMCX1,UBE2A,GHR,CCT2,CXCL11,UBE2D3,SOCS4,IRF1,CUL2,PYCARD,SLC6A8,TRIM23,CDC16,LTBR,GNB1,CASK,ASB8,INPP5E,RASGEF1C,MAD2L1,CDK5R1,MAP2K6,CLU,ANAPC11,LMO4,FOXP3,CCR6,APOBEC3A,ID4,PPP5C,XAGE5,THAP2,TIAM1,TRIM63,SENP5,CTNNBL1,IDH3B,JAKMIP1,SWAP70,MYL12A,ITK,TRIM46,DNAJC1,HCLS1,SFN,RAG1,ENY2,RING1,GNAI3,MRPL50,SLC30A5,KLK3,SMARCD3,PPP1R2,AK2,SOCS5,MDM2,MRPL13,WDR83,CDK8,PFDN5,COX10,CNP,TFG,RND3,TRIM8,DKK3,HRAS,RAB11A,ASMT,L1CAM,IKBKB,AKT1,FGD2,TRIM3,IKZF2,PGM1,LIG3,PRKCQ,RNF141,ALKBH2,KLK9,DOK4,ARHGAP1,NCKIPSD,CD99L2,PRIM2,TRIM32,NFE2,RSPH1,ZDHHC15,MAP3K12,E2F6,ZMPSTE24,FBP2,RPS4X,SOX3,CIB3,ACO1,PCK2,CAMK2G,SRP54,SCFD1,SATB1,FGFR1,SHC1,PPP3CA,NME2,C1GALT1C1,EIF2AK2,AGK,ANAPC2,FBXO32,TRIM27,COPS2,RAB31,ARMCX5,DYRK1A,DRP2,AGER,RAB18,IDH2,FKBP14,INSM2,TRIM37,HECW1,PTTG1,PTPN1,RMND5B,NOVA1,SEC63,RBBP7,TRIM21,ARMCX2,CAMK1,SNX2,ZDHHC14,ADRB1,FRMD8,USP2,HEY2,RABL2B,FAM199X,ARHGEF6,DLAT,FZD4,FBXO42,SERPINB10,MCM8,ABCB1,MLF1,ZBTB33,JAK1,BAG2,GRAP,RAB3B,KPNA1,CSNK2A1,TMEM74,CTNNBIP1,GNG7,PLP1,RNF41,RS1,KIT,PHF1,LMNA,CFL2,SNX5,ZMYM2,MMP9,BUB3,MYH2,JUP,EXT1,VRK1,PGK1,DNAJC5,XPOT,CXCL1,SRSF1,ITGA2,COX6B1,MAPRE2,NLE1,EPHA2,HSPE1,TSPAN7,SERPINH1,PIK3R1,DCLRE1C,RAB4A,DHX16,POLD2,KDM2A,LHFPL1,SUMO1,HSPB1,GAS8,CDKL2,LMBR1L,CBL,COPS4,KCNK17,MRAS,CXCR1,NEDD8,RAB28,MDH1,ELK1,RASGRP2,ST13,MMP14,RAB6B,WWP2,RAP1A,FBXO30,VAC14,LDHA,YES1,GSK3A,GAPDH,UBL4A,FATE1,HECTD3,DNAL4,HDAC5,IDH3A,RFC5,THRAP3,MED13L,NSDHL,XPO1,EXOC2,XPO5,POU3F4,RNF103,APOBEC3C,RNF146,SAP30L,CIRBP,NEK7,NTRK3,PICK1,PHKG1,TSSK1B,UBE2B,CSE1L,AGAP2,GLE1,FBXO3,FAM3A,NEK9,TNFSF10,CDK5RAP3,FURIN,RAB3C,MTAP,TNFRSF9,DMAP1,NFYA,PPP1CC,DUSP1,BATF,ANP32B,ACVR1,IFT57,BCL2L1,DCAF8L2,SPOP,NR0B1,CCND1,SASH3,CASP4,FBXO9,COX7A1,KLF10,DIRAS1,ITM2A,ADH1A,BMPR1A,ARHGAP21,RHCG,MCM6,INPPL1,ASB1,FBXL3,KIF2A,RGS10,POU1F1,CYC1,SLC35A2,MCPH1,NKRF,ID1,RNF152,NUP107,DEK,PRKD3,BPGM,CDKN3,EGLN2,DUSP9,AKR1A1,CXCL9,RBPJ,RAP2B,TNFAIP3,TRAF7,CDC5L,DUOXA2,MTMR12,SIRT7,ETV6,RABIF,GNAQ,SPRED1,RAD1,NFE2L2,USP46,SMAD2,PITPNB,NONO,POLL,SIKE1,SNX3,NCOA5,RUVBL2,IGF2BP1,LSM6,PEBP1,PROX1,PRKX,CX3CL1,FGF13,NAB1,IL5,USP39,CERK,CBX7,USP38,TAF2,CDK6,SGMS2,NCSTN,P2RY10,SLC38A2,FKBP4,PSKH1,SMURF1,UBE2N,CTNNB1,RAB8B,SOCS2,RHOJ,CBLN4,WWP1,CALR,TRUB1,PKIG,JUN,SUMO3,OPHN1,OGG1,CCR3,RAB23,PPFIBP1,PTGER1,TNFSF18,RAB33A,RNF167,TOB2,RNF26,RAB13,CDK5,GNG3,UTP23,RNASEL,NDC80,NEK2,NFKB1,PRKAG1,RAB5A,PC,APOBEC3D,HNRNPK,TMEM31,F10,MAFG,DYRK2,FOS,EGLN3,DYNLT3,RAB14,RIOK2,RPL26,RPN1,PPID,PAX6,STAT1,ZNF507,FANCG,LMBRD2,ZMYM4,BTG1,SERPINA5,BICD2,ASB3,RNF122,USP14,RAN,TSC22D3,CXCR6,GNA14,HSPA14,CXCR4,PGR,POLR3B,HDAC6,RNF39,ANAPC13,PAFAH1B2,COPS7A,RNF20,DDX42,NUP153,OTUD6A,PPP1R16A,CXCL14,ADAMTS1,RRAS2,RERG,BNIP3L,DAPK1,SESN2,KLHL15,RABL3,UPF3B,ZCCHC12,NFYB,PPP1CB,YWHAB,NUS1,PLEKHA8,MMADHC,TMEM164,APLN,CRKL,SOS2,KDSR,DNAJC27,FBP1,SLITRK2,CDKN1A,RP2,FOXN2,PPFIA3,CLIC2,NLRP1,RBMX2,NDE1,LDHAL6B,TNFRSF14,SNIP1,UBE2D1,RAB1B,RGS5,CBX5,TOP3B,GNAI2,CAB39,KLK5,DDX4,PCGF3,TCEAL7,MAX,RHOB,TOPBP1,G2E3,TRIM11,PROM1,E2F4,PPM1G,RPRM,FUT1,LITAF,ARL4A,WDR44,MEF2C,RAB2A,CTNNA1,CCNF,STK11,DYRK1B,TESK2,WIF1,RPS27L,LAMTOR3,STAT6,SNX24,TP53INP2,INPP4A,FKBP10,FGFBP2,EZH2,RAB9B,AMT,UBE2F,FOXP2,TIMP1,IL6ST,CYTH1,DDX5,EIF4A3,SMAD3,RAP2C,PPP2R1A,STK38,PRRG1,DNAJC10,RAF1,DET1,WEE2,PCDH19,RNF14,PNP,RAB5C,SCYL2,RAB37,PHKA1,FBXO25,DNTT,OSBP,GOLGA5,SSRP1,BECN1,LMNB1,MED21,VMP1,HSPA8,PPP1R12A,HSCB,TFEB,EED,DYNC1I1,ACSL4,TRIM24,CIB2,PPP2R3A,FZR1,SMAD4,SMARCA5,DRAM1,BAK1,ELK4,CD274,FAIM,FOXP4,RNF126,LDHB,DDX39A,IGBP1,AKAP12,NUP37,TRIM5,EIF4E,COX4I2,CDKN2C,ITGAV,MXI1,USP5,MOSPD1,RNF113A,EFNB1,FCHSD2,CSNK1A1,ITGA6,UBE2M,PIR,TRIM10,TFE3,UBE2E3,SMC4,RAB22A,UBE2V2,AK5,RFC2,DERL1,CSNK1A1L,SOX2,LNX2,SNX18,ACTB,PAX9,PRKAB1,GNB4,CNTN1,STK24,NFKBIB,MMP21,RAC2,PGAM1,LRP6,RNF121,FOLR2,PTPN22,SOCS3,PDHA1,NOS1AP,BCL10,DNAJB2,RGS2,DUSP19,NME1,PPP4C,NPR2,CDK4,PFDN4,BRCA1,TRAF2,RAB30,STAU1,PLA2G12A,TSN,KLK6,DNAJC3,SERINC3,PDCD4,LDOC1,CREBBP,TRIM54,RCE1,RASGRP3,RGS19,RAB33B,CDC42EP3,MCM3,KDM4B,RUVBL1,GIT2,NKIRAS1,ICAM3,RAB3D,SRC,RASL10A,IDH1,GNG13,SAT1,GNG2,GTF2H2,MAP3K11,PIK3R3,LANCL1,MORC4,ERH,PIP5K1A,PTGER4,TRAF3IP2,UHMK1,NLRP6,METTL2A,FAM162A,CCNB1,AKAP14,CHRDL1,CSRNP1,SYP,ATG4A,PADI2,FUNDC2,SFRP4,GPHN,HSP90AB1,POLE4,HMG20A,IPO8,DSTYK,CCR2,GNG5,APOO,TMC7,SNX17,TNFSF13,TOP1,F9,PGPEP1,SERPINI1,IDO1,PPM1D,CXCL12,BCL7B,ARHGAP25,DNAJC22 |
| 9.364e-11 | -23.09 | RPL13 (ribosomal protein L13) | protein interactions | 6137 | 647 | 256 | 19454 | 5460 |
DRG1,MAGOH,RIOX2,WWP2,RPL6,DDX50,IFI16,DDRGK1,NGDN,CTNNB1,MRPL9,LYAR,RPS10,EIF2S1,GLE1,RPL18,RPS23,MAGEB10,RPS7,NUP42,KRAS,CBLL1,RPL28,RPS4X,PABPC1,RPL31,H1-10,ATG3,MRPS25,FTSJ3,NSA2,RPS26,ICAM1,SFN,MYC,THAP7,ZCCHC7,TRIM29,MATR3,RPL10,CMTR1,MRPL13,MRPS18A,PIH1D1,RPL27A,STAU1,UFL1,MRPS7,RPS28,RAB5A,HDAC5,HSPA8,MRPL34,SF3B1,SNRNP70,RPL24,TUBG1,CENPL,IGFBP4,RPL10A,RPS2,NOL12,CDK12,ENY2,COPS5,CD81,CSNK2A1,RPS27L,FZR1,RPS16,DNAJC1,CAND1,SURF6,CDC5L,RBM42,MYL12A,TMPO,DKC1,RPL32,MRPS9,DNAJC2,RBM34,TFCP2,TP53,MRPL47,RPSA,KBTBD4,UBL4A,IMP3,IMP4,MRPS33,H3C1,RPL17,MEPCE,MRPL52,RPL3,TRIM23,RC3H2,MECP2,UBE2H,CDKN2AIP,RPL7A,SMARCA5,CARS1,RPF2,CEP70,DYRK1A,RSL24D1,SRPK2,RPS3,PSPC1,RBMX2,FGFBP1,CSNK2B,SSR1,RPA2,ZNF770,HEXIM1,DYRK2,CFTR,MRPL10,MRPL40,MRPL41,RPS15,HSPA5,MARS1,PML,BAP1,RPL27,RNF113A,TWNK,EXOSC4,WDR12,MRPL18,RPL23,DICER1,MRPS26,RB1CC1,RSBN1L,AHSA1,MRPS35,MAP3K14,RPL7,PHB1,FOLR1,RPL9,RPL8,RPLP2,RPLP1,HP1BP3,CHMP4C,EZH2,SART3,RPS11,MTMR2,POLR2C,B3GNT2,RPL29,MAK16,TRIM37,TNF,G3BP1,RAD21,GTF3C3,RPS24,NOA1,ILK,RPS5,CUL2,NOP16,CUL3,ZNF668,MRPL16,RPL7L1,RPF1,RPL35,MRPL23,RANBP6,RPL19,FAU,ZNF22,RPS9,SEC61B,RPL37A,EMC9,ANXA7,MAPKAPK5,GPC1,NOP53,UCHL3,G3BP2,MPHOSPH10,SPP1,SPATS2L,MOV10,GTF2E1,HDAC6,MRPL50,RPL35A,CDK9,RCHY1,RPL12,LLPH,SRP72,MRPL51,TOPORS,MRPL11,FBP1,RPL15,FCF1,MAP2K3,TAF1D,VRK1,HUWE1,PAK1IP1,SMN1,RPS13,MRPS18C,NKRF,FAF1,RPL23A,PPP1CC,RPL26,RPL13A,NDN,RPL22,METAP2,EIF4A3,PELP1,CCNF,RPS12,PTEN,RPS20,GSK3A,PRKRA,METTL14,MRPS34,ZNF574,RPL26L1,RPLP0,TPT1,EEF1E1,UBA52,RPS14,CDK7,FBXW7,RPL4,HMGB1,NPM3,MRPL17,NF2,BRIX1,MRPL20,AATF,UTP23,RPA3 |
| 9.706e-11 | -23.06 | organic substance transport | biological process | GO:0071702 | 1881 | 676 | 18204 | 5365 |
DNAJC19,FCHSD2,SLC43A2,PEG10,RAB4A,SEC61G,THOC2,ABCB9,PREPL,HNRNPA1,GOSR2,TOMM40,SLC6A2,ARFIP1,RTRAF,FAF2,SLU7,SLC25A1,ZFAND6,GOSR1,SLC35A1,G6PC3,HSPB1,RAB9A,YWHAH,HNF1B,NXT1,RAB18,REP15,SCG2,SLC6A7,CHRM5,CSF2,BTF3,STX8,HSP90AA1,SFXN2,SYNDIG1,UNC119B,CNIH4,MTCH2,GDI2,SLC48A1,STK3,SNAP25,CPTP,CAV1,STARD3NL,MCOLN1,NECAP2,TNKS,SMG5,MPC1,FKBP1B,BLOC1S3,RAB1A,NME4,AGAP2,SLC25A17,VTI1B,COG1,AP2M1,PLEKHF2,IFT22,TNPO3,HSPA5,SMAD2,SNX3,TRAM2,SLC38A3,ALKBH5,AQP3,SLC6A8,VAMP5,CCDC186,AP2A1,SLC25A51,SLC19A2,ATG9A,MTM1,ARL6IP5,EGR2,PSEN1,PLSCR3,SLC7A14,LCA5,SLC6A3,CD209,CHP1,OSBP,SLC2A3,SEC22B,RAB29,GJB1,CPT2,CPT1B,JAGN1,SLC7A8,SLC5A6,CMTM6,SELENOM,TRIM37,RAB3B,TMEM115,TOMM22,DHX9,EIF2D,VAMP8,RAB1B,FABP7,NAPG,PEX13,RABL3,VPS4B,RBP2,THOC3,AP5S1,TIMM10,FOLR2,SNX33,TOM1L2,PPY,TVP23B,SRSF7,HPS6,TTC8,SLC38A9,COPZ2,CSE1L,ACTN4,SLC35A5,OS9,XPO5,JAKMIP1,SLC25A24,SLC19A3,HGS,RAB28,AFTPH,PRKCB,FABP12,RABL2B,VIPAS39,CRHR1,SLC66A2,WDR11,VTA1,GHRL,ARL5B,AP5M1,PLA2G12A,BAG3,CBL,BECN1,CBLN1,POLA2,ATP1B1,LRRC8C,NAPA,HBB,TST,RAB13,RAB3A,GNPTG,ABCC5,TAF7,ARF1,STARD5,STK4,SVBP,TMEM30A,SLC7A9,TP53,KIF3B,RHCG,NCBP2,SLC25A39,VPS4A,EHD1,ARHGAP1,TRAM1,ANO3,SRSF1,COMT,CRABP2,SNX20,LARGE1,CHMP1B,SLC15A1,HSPA8,SCAMP5,RPAIN,TOMM70,NETO1,TMED7,AZGP1,ARF4,NUP42,SEC14L1,LRRC8A,SLC4A10,SLC51A,CLN8,AP1AR,SNX2,KPNA2,SRP54,SLC6A4,SAMM50,RAB3C,SLC17A5,CHCHD4,APOC2,AGAP1,SLC35D1,CYB5R1,SLC25A11,CEP41,RAB32,IPO8,UPF3B,SLC22A6,OSBPL8,TMED5,GABARAPL2,MLC1,UFD1,TSPO,RABIF,CD3G,GLE1,SESN2,CALHM3,STX12,CETN3,FYTTD1,CHMP5,SLC35E3,APOO,TNFAIP8L3,SLC25A12,LIPA,RBM15B,LIN7C,SLC16A1,CYP7A1,ANKRD50,DESI1,SLC15A2,ARCN1,CHMP4C,SCFD1,PPARG,CCDC22,YIF1A,RAB39B,BET1,RPL23,GRPEL2,VAPB,APPBP2,POLDIP3,RAF1,SLC39A10,PPT1,RANBP6,TMEM144,SLC25A4,SEC13,RAB2A,VAMP7,RAB6B,RBP5,SNX14,RAB11A,ING1,ERLEC1,SEC22A,PITPNB,RANGRF,VPS28,CTDSPL2,RAB11B,ARL4D,GOLPH3L,CDK5,STX1A,RAB6A,PITPNA,SNX22,RHOB,VAMP2,TOMM20,TIMM23,RAB37,PLEKHA8,FOLR1,SPRN,TBC1D13,PEX3,HSP90B1,ATG3,CIDEB,CDKN1A,RAB31,ANKH,GPR89A,SLC22A12,STRADB,SLC25A5,NUP35,LRRC8D,TRIM23,CTTN,LMAN1,GJA1,RP2,SEC61A1,CFTR,TBC1D17,SLC22A8,RAB9B,EXOC3,TBC1D5,ARF6,EXOC5,CASC3,SLC29A1,EXOC8,PLSCR1,SLC35B4,SLC2A8,MYO6,RAB23,MACIR,DNAJC27,G3BP2,ACVR1C,BBS5,PEA15,THOC6,GPM6B,GLTP,DUOXA2,SLC6A12,MX2,KPNA1,ARL11,SLC7A1,COPE,SEC22C,EIF4E,TRAF3IP2,ERP29,AHCYL1,LAMP2,TOM1L1,IL6,CETN2,CHMP1A,DDX39B,VPS26B,TNPO2,AKT2,VPS33A,AP1S2,CA2,HSPD1,SLC37A4,LDLR,CPLX3,AP1G2,TMED1,MIR130B,MIA2,GRM1,SNAP29,LRRC8B,CLIP3,FLOT1,SNAP91,SLC1A3,SERPINA5,XPOT,CHMP2A,AQP2,SAR1B,PEX5L,SLC25A42,EDNRA,TIMM29,TXNIP,VPS18,SLC32A1,OPTN,SNAPIN,PNPLA8,CD36,CHMP2B,SCAMP2,SLC35C1,SLCO1A2,SLC38A7,DNM2,ABCC2,ATG7,FAM53C,SMURF1,ILDR1,EXOC1,MCL1,GUK1,HM13,RHBG,SFN,SLC35A2,AQP11,CACNG3,SFT2D2,TIMM17A,PPP1R10,FABP4,SNX5,ROMO1,NFKBIA,UCP2,MAGOH,AP1M1,RAB5C,RFTN2,ENY2,SLC18B1,SNX18,ABCB1,CAMK2G,NPC1L1,NSG1,CALR,KDELR2,SLC1A1,RAB3D,VPS26C,SLC1A2,RHAG,IFT25,LMNA,SLC45A3,PPP3CA,FAM53B,SLC6A1,PEX26,ARFGAP1,AKT1,AIFM1,GABARAP,SLCO3A1,VPS26A,TMED4,VPS39,FKRP,SELENOS,SLC25A31,DRD3,ATP8A1,DDX39A,TSG101,APOC4,STXBP1,VLDLR,STX7,SLC25A26,PLA2G5,KPNA6,SYVN1,FAM91A1,RAMP3,TOMM40L,SLC25A10,PRKCE,DERL1,SLC4A8,BCAP29,TUBA1A,RAB27A,CYB5R4,XBP1,FHIP1B,CPE,SNX12,CCHCR1,SLCO1B3,SLCO2B1,SEC61B,TIMM8A,ARRDC3,NUP50,NUP153,TGFBR2,SYNRG,CARTPT,ATG4C,SLC7A4,PAFAH1B1,STX5,ARFGAP3,SEC23A,SLC13A5,CD47,SERINC3,NUP107,RAB22A,SNX10,HBA1,THOC1,SFTPA1,STX10,RAB8B,NEO1,GPIHBP1,SURF4,ARL4A,TOM1,PHAX,MAGOHB,ZFAND2B,LRP10,SLC25A21,CHTOP,SH3BP4,DAG1,OLFM2,PPID,PHB2,ABCG2,HIKESHI,ZMAT3,SLC25A23,STX18,SLC6A11,PMP2,HNRNPA2B1,SQSTM1,LEP,RAB40AL,PARP11,SNX17,AKR1C1,SEC62,GOLGA7,SFXN1,AP2S1,PRELID1,MECP2,FABP5,SIGMAR1,SEC61A2,SLC38A1,KDELR1,CTSA,TOMM6,SLC38A2,SYS1,SNX24,LYPLA1,EHBP1,SLC6A6,RAN,PIK3R1,ALYREF,SNCG,MTX2,PIK3R2,SNX1,AGK,MIR301B,TRIM3,SLC25A32,CPLX1,TIMM21,SLC52A3,STX17,FZD4,TOMM7,AP3S2,STARD4,NTRK2,SNX11,SHOC2,BET1L,TMED3,BICD2,SPTBN1,ATG4A,ATG16L1,SLC7A11,UBAP1,SLC2A1,KCNJ10,XPO1,CD63,NUP37,PLSCR4,VMP1,EIF4A3,RILPL2,YKT6,CLTRN,NPC2,SEC63,TIMM13,STAR,TFRC,RAB33B,NXT2,SLC23A2,RINT1,SYK,CLU,DERL2,SCG5,ARFGEF1,RAB14,ZDHHC17,HDAC6,LIN7B,S100A8,TESC,STX11,TMED9,GRPEL1,SELENOT,ZC3H11A,STX16,NHERF1,IGF2BP1,SLC16A4,PML,NUP62,SLC35B3,NECAP1,EXOC2,EHD3,ARL6,SLC25A44,TRAM1L1,SRPRA,CBLN4,MRPL18,KCNJ8,DRD1,CACNB4,SLC16A10,TIMM8B,SNAP23,CD2AP,SLC25A20,STX6,HBE1,FXR2,VPS16,RAB5A,TSPO2,NDP,USE1,DNLZ,GRM2,YIPF5,C2CD2L,RAB35,TRMT10B,VPS54,PICK1,VAMP3,RAB19,VIP,ESYT1 |
| 1.010e-10 | -23.02 | ALDOA (aldolase, fructose-bisphosphate A) | protein interactions | 226 | 267 | 124 | 19454 | 5460 |
SPOP,TRIM23,CDC73,UBE2H,AKT1,CFL1,CFL2,NDN,LDHA,KCTD9,SRPK2,VIRMA,CCNF,ENO1,TRIM24,JUP,RPA2,METTL14,HSP90B1,UBE2M,HEXIM1,UBA52,CFTR,FBXW7,CRYZ,BAP1,SOD1,RPA3,PML,FLCN,PGK1,HSPB2,GPX4,FOXP1,USP15,CALR,EMC4,ISYNA1,HDAC6,GAPDH,GLO1,FZR1,VCPKMT,LMAN1,COX4I1,PREP,TFCP2,GPD2,HBP1,SOD2,RNF8,H2AX,MAP1LC3B,HADH,PPIF,HUWE1,TRIM63,HSPE1,TGFBR2,RIGI,CYTH2,ATP5PF,HSD17B10,CKB,YWHAZ,ATG3,BRCA1,HSP90AA1,RIT1,MYC,ACO2,CUL2,CUL3,BTF3,PSMD4,TAGLN2,DYNLL1,TENT5C,UMPS,TUBB,APEX1,TNPO3,ESR2,VPS18,ACAA2,PIH1D1,WDR77,UFL1,EMC1,ADRB2,DDX39B,NMRAL1,HDAC5,HSPA8,PSMA3,EP300,AGR2,AHSA1,PDIA3,HNRNPA1,DDRGK1,SUMO2,HSP90AB1,FABP5,FOLR1,EZH2,CHMP4C,NGB,NME1,RAB4A,B3GNT2,RAF1,ACTN4,NCSTN,ISG15,GABARAPL1,MSX2,KRAS,TRIM37,FKBP2,IMPA2,HSPD1,MT3,PCNA |
| 1.025e-10 | -23.00 | MTERF3 (mitochondrial transcription termination factor 3) | protein interactions | 51001 | 353 | 155 | 19454 | 5460 |
GFM1,TWNK,UTP23,MRPL20,POLDIP2,MRPL41,MRPL40,NME4,MRPL17,RBMS2,MRPL10,NDUFAB1,PDCD1LG2,MIR34B,MTRES1,ZNF574,MRPS34,QRSL1,MRPS28,SYNGR1,EIF2AK2,MRPL53,MRPS21,TUFM,RPL26,PYCR2,RPF2,NDUFAF2,CDKN2AIP,IGF2BP1,SYP,MRPS16,YIF1A,HSD17B10,ERG28,MRPS18B,ATP5PF,STX8,MRPL52,RPL17,MRPS18C,FASTKD5,MRPL22,HSPE1,HNRNPK,MRPS33,METTL15,BCS1L,PPIF,DDX39A,NDUFA2,MRPL47,MRPL11,ATP5PB,MRPL49,MRPL51,ILF2,GFM2,NDUFS3,PRR3,MGME1,ALYREF,SSBP1,MRPS9,SYNCRIP,MRPL24,MRPS23,DBT,DKC1,ATP5PD,RBM42,PRNP,MRPL50,CAND1,RPL35A,COX5A,ATP5MG,GRSF1,ADGRE2,SNRNP70,HADHA,EXD2,NGRN,MRPS7,HSCB,NDUFS2,TRA2B,MRPL12,FUNDC1,SEC62,AGTRAP,PABPC5,NDUFA5,ATP5PO,MRPS18A,MRPL13,RPS9,DLST,TACO1,ESR2,RPL19,NDUFAF4,MED17,ATP5F1B,MRPL23,MRM2,HNRNPAB,PMPCA,HNRNPC,AUH,MYC,MCAT,MRPS25,FBXW11,NOA1,CIRBP,SRSF7,MRPS11,HINT2,HNRNPA2B1,HSPD1,HNRNPDL,MRPS17,SRSF4,KGD4,VDAC1,ETFA,NUP42,ATP5F1D,HIGD1C,ETFB,HSDL2,NDUFA12,NDUFS6,PDHA1,FAHD1,GATD3,SRSF10,NDUFS8,ATXN10,PAIP1,HNRNPL,TRA2A,DDRGK1,MRPL9,NDUFV2,HNRNPA1,RPL6,STOML2,MRPS35,CLPX,MTRF1,MRPS26,MRPL18,RHOG |
| 1.026e-10 | -23.00 | adenocarcinoma | COSMIC cancer mutations | adenocarcinoma | 16668 | 4822 | 16828 | 4835 |
PAQR3,CREBZF,TRIM36,MRPS18C,NT5DC1,JAK2,PROK1,HSPB2,STK3,CBLN1,COMMD9,LY6H,TNKS2,LILRA2,DCAF12L2,PTP4A3,PLSCR1,ZBED1,CTXN3,RB1,CORO6,OIP5,TRIM29,PNMA3,DPH5,MCL1,FAM53C,TMEM127,GSTA2,HCAR1,NDUFA1,HFE,GPR35,DDAH1,ALG11,CAV1,B4GALT4,YIPF3,TCEAL8,LXN,RPS2,ITGB5,RGL2,TMEM205,NDUFC2,TRIM34,ICOS,NINJ1,BLCAP,AKR1C1,CSNK1G3,RAB39B,MRPS11,HUWE1,ABHD10,PRND,CPLX2,CNTROB,FTSJ1,SREK1IP1,UBE2L3,CCIN,PMAIP1,TTPAL,MEPCE,EIF3G,SPEM1,CYP3A43,PDE4B,MAGED2,GJA1,SLC29A1,SURF2,REEP4,RNF222,AASDHPPT,CCNA2,TM4SF20,SLC8A1,OR8H3,CAPN2,LSM14A,STARD3NL,YWHAZ,OST4,ABHD8,ICAM2,TNR,OR6X1,TM4SF18,BOK,CEND1,ZNF511,EHD4,FAM81A,SLC25A1,STAMBP,HNRNPF,HOMER3,MAGEB10,CXCR3,OR4K2,PCGF6,GRM1,TAF1D,ADORA1,SPATA2,SLCO3A1,KCNJ10,SHPRH,PLG,DMTF1,CDK12,DLK2,PSMB7,FBXW7,TNFAIP6,CTU1,EPHA4,GXYLT2,KCNJ2,ARL4D,TXNDC17,LIAS,CITED1,GCLC,PSMD10,NPY1R,TNNI3K,CPLX3,GPC1,GPR17,PLCB1,PRSS23,ZNHIT6,ARL2BP,ING2,SPP1,FAM149B1,FRZB,CHRM3,TSR2,XAF1,PICALM,COX6C,LST1,PIK3AP1,RPIA,VTA1,FEM1C,COCH,NUDT2,PSD2,ATP1A3,GH1,BAX,PEBP4,GSTM4,CRTC2,NPM3,TMEM38B,TSPAN15,FAM83B,SNRNP40,IVNS1ABP,PIK3CA,PSMC3,CDH11,JAKMIP2,TMEM185A,NDUFS2,PAIP2,MAD2L1BP,TMEM47,AP1S2,LY96,TAB1,SF3B1,APEX2,ADORA3,AKR1B1,CNN3,RBM27,ZBTB39,CPT1B,ANKMY2,ZNF263,TPPP3,CA2,SNX10,SGTA,PET117,USP6NL,MTDH,GSTCD,TMED9,E4F1,DLST,GTF2F1,SSX2IP,BCL6,SYNPR,ELMO2,LYPD6,TRPC1,ASPA,BCL9,DR1,CBX3,HS2ST1,GTPBP8,MIS12,CAND1,HSD17B10,PRNP,GABRA1,TMEM89,CDC20,ZDHHC4,WDR5B,TIMP4,ACCS,XRCC5,SNRPG,ADTRP,PEX13,AIPL1,TBC1D25,TYROBP,FHOD3,SLC35B3,NHEJ1,WDR11,IL2,SEC13,NBN,VMAC,TNFAIP8L1,MPPED2,PRL,CDC7,SLC19A3,OLR1,FBXO8,NDST3,RBBP8,MGAT4A,SGMS1,CYP2C9,IGSF11,MRPS34,TRIM45,ATAD1,DUSP21,PHF13,RPL26L1,CGGBP1,SESTD1,CARTPT,FOXA3,KLHL1,NF2,PARP2,BANF1,ABHD12,TNF,GGH,CYGB,NUDT9,IL17F,PPAT,LZTFL1,SNRPB2,TFB1M,SUMO2,CHRAC1,CCR4,KLF3,MT1E,CD81,CRISP1,ELK3,LRRC40,DPH3,UBE2E2,TRAPPC13,POLDIP3,POLR2L,RHOBTB3,HGS,FSTL1,DBR1,TAS2R13,TMEM170A,RNF133,COX6B2,WDSUB1,GNRH1,ZNF451,PRKCE,PRKRA,TSPAN17,SNRPE,RRAGB,DLGAP4,CMA1,GRIK1,RASL12,IL18BP,ANXA4,GALNT2,THUMPD1,GORASP2,PELO,GMPS,TTC9C,CCR7,IGF1,RXRG,SNAP25,ELFN1,DMPK,MBD3,CDC23,BRAP,TANK,SYNGR3,MPG,RDH11,KCTD3,PIH1D1,SSPN,GNGT2,CNPY1,LRRC8A,RP9,GALC,ELFN2,OR5M9,HAUS2,NKAP,LBX1,KLHL25,OR8B4,TMEM165,SULT1B1,RPE,MFAP3L,FAM3C,PTP4A2,VEZT,SLU7,IRF7,SLC25A5,PRR13,LYZ,TOPORS,WSB1,OAZ1,FAM151B,ZNF518B,MACROD1,CYBRD1,ADCK1,SLC35E4,FAM136A,MECR,MRPS17,SGIP1,FEM1B,UBE2G2,MRPL9,SUPT3H,UPRT,FXN,TOX4,KLRC2,RAMP3,CPNE2,CYTH4,TMBIM1,IFT172,TRIM26,IER3,NUCKS1,CENPL,RPS10,SPRY1,ETNK2,CCDC106,CLDND1,TRAF6,TBCCD1,KCND3,FUBP3,ROCK2,KRIT1,VPS72,TKTL1,GIN1,RPL18,MGMT,MDC1,TRAPPC6A,SP1,CCSER2,ITM2B,MTCH2,IMPA2,TRAM1,TADA3,UBA52,FUNDC1,ECHDC1,AP1M1,TMEM196,ARHGAP12,PFKFB2,EIF5B,SRFBP1,DIRAS2,MREG,ACER3,YTHDF2,ANKRD6,PDE12,FAM161A,EDA2R,LCORL,LMO2,FKBP1B,MAGEC2,PSEN1,OR13A1,SSBP4,CLEC6A,KCTD17,RASSF8,TLCD1,AQP11,RBP2,ZNF581,SUCLG2,DUSP3,PDE7A,KIF3C,CIAO1,ATP8A1,VPS18,GHRL,NAA16,RUNX1,RPS20,SLC12A2,GJC1,SCML1,TYMS,MED10,TAPT1,ZFAND6,AIP,CD40,TNFSF15,SLC6A2,CRY1,NOG,MED22,ARFGEF1,PMPCA,TLR8,TNFSF8,CDIPT,ZNF428,PDE2A,PYCR2,SCAND1,PSMD7,PLAC1,CDK7,SIN3A,CTTNBP2,RGN,FKBPL,RAB6A,OR4A47,TMEM100,DCTPP1,CPXM1,FBXL4,CD34,UNC79,THAP1,EID2B,PRCP,CCDC90B,RGP1,TRAF3IP3,PIWIL1,SRPK2,TAB2,GADD45G,RNASE9,PRSS8,YPEL4,LDB2,TMEM107,RPA2,FBXW4,P2RY4,CD209,TAS2R7,ST3GAL2,IP6K1,IL2RB,PTGFR,SPINK9,SLC25A24,GK5,SSNA1,GLCE,TRIP4,RPL10,STAR,SUPT5H,PDCL,CNPY3,SRI,NCAPG2,CYP4V2,APLNR,GPR160,POLR1D,PSMD3,DTWD2,FAM133B,RNF10,KRTAP8-1,POLE3,OR51E2,GP9,TEX261,OR4D5,ZDHHC16,MDFI,PPP1R11,RAP2A,MSH6,TRIM44,NR1I3,LRP10,PAIP2B,VAV2,CCDC3,ITGB8,BTG2,TMEM229B,GNB3,CMC1,NUFIP2,HINFP,WDR45,THAP8,MPV17L2,CRYBA1,NRM,SERTAD2,GNA11,HSPA5,HSPB6,FAM20B,TICAM2,FHL3,PPWD1,GPRASP2,PQBP1,TMEM81,EXOC3,SAP18,CAP2,TIA1,SPG21,SLC22A6,DDR1,RNASEH2C,HSPD1,EIF1AX,NUPR1,TMEM115,NPC2,PIAS1,PNPLA4,TCEA2,LRRC28,PARD6A,DPEP3,TMEM183A,BTG3,CD9,RUSC2,OR1M1,IGFBP3,GADD45A,GRPR,SLC25A27,VPS54,RBMS2,TGFB2,S100A11,ZNF622,ATG9A,THOC3,MX1,BOLL,PIGA,GLOD4,NRGN,CSRNP3,TRAPPC3,LDB1,WNT2,GMDS,BIRC5,MFSD3,YKT6,VPS26B,ANKH,ESYT1,F2,ARL5B,CAMKV,EDC3,HAPLN2,SAP30BP,AANAT,UNC45A,PRSS35,FKBP2,TBCEL,GMNN,CYP26A1,ISG20,TMEM87A,NUDT1,RALB,DTL,PSMG2,SNRPA1,SNN,CTDSPL2,ABHD2,CEP70,ARL6IP5,ANKRD46,CCDC22,NDFIP1,KDM1A,GFM1,EMX2,CENPM,SEC61G,HOXB8,SSH3,FZD6,MET,SLC7A11,RETSAT,POPDC3,GAL3ST4,PRM1,ADIPOR1,UBE2V1,MT1X,SERPINB9,TIMMDC1,SNX11,RPLP1,TRNP1,HELT,IMP4,PDE6A,B3GALT4,DLG3,RHOU,TMEM176B,BHLHA9,RPL22,CEBPE,RBM5,CTLA4,ATF3,RANBP1,DEFB1,IFRD1,ACSS2,PRSS37,PDLIM3,MAP1LC3B,KCTD16,SLC15A1,ZBTB6,PLEKHF1,AHSA1,TEX19,ZNF655,TRIM62,GPR78,HNRNPAB,TMEM168,TMEM220,USE1,ST8SIA4,CD200,LRP3,STRADB,SIAH1,NCK1,PHOSPHO2,SCG5,OR6C4,NMRAL1,MAT2A,TRAPPC2L,TMEM198,RFX5,CMBL,COX7B2,CDKN1B,MEA1,TAF9,SCHIP1,HMGN4,HAS3,PRPS1,OLA1,MGST3,BAD,TSPAN3,NOC4L,UQCRC1,AKR1E2,CRHR1,GDAP1L1,SSBP2,PDCD10,LRRN4CL,ZSWIM7,WTAP,RPL31,PTGER2,CDR2,NETO1,NAA30,C9orf72,DOK6,SEMA3C,HERC3,PSMB4,CGRRF1,DDX39B,IRF9,HSD17B8,LSM4,RSL24D1,TRAF1,KCTD20,RASSF4,SERPINA3,SKAP2,CLK1,BRS3,ZMAT3,KCNG3,CHST10,SOX9,PSMC5,APEX1,PRSS1,AKT2,ITPRIPL2,GAB1,JMJD8,TICAM1,HS3ST3A1,LCN1,RFC4,HIGD1C,TLR5,COTL1,PNPO,OR2D3,GPM6A,PRELID1,ETFA,APMAP,PSMG4,RIMKLB,AQP3,CD59,ECD,S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KCNS1,SPRYD4,LRRTM2,API5,RPL9,DGCR8,RNF5,TST,LAP3,ADIPOR2,EFHD1,C2CD2,RCCD1,EXTL2,ALPL,SLC20A1,TRIM6,PYGB,FOXP1,SLC4A10,PSMB9,PDE8A,HOMER1,KCNJ8,SAMM50,ENC1,GINM1,ALDH1A3,AHCYL1,IZUMO4,ADM2,HNRNPH2,HMOX2,CLIC4,NPTX1,COX11,MAGED4B,TFPI,PAAF1,PRKCA,MMD,MAP3K21,WRAP53,BET1L,KLHL26,TRAPPC4,EEF1A1,UCHL3,GAS2,RPL39,TTC33,OR2AT4,C2CD4C,TMEM108,FAR2,BRD3,SURF6,TESK1,DVL2,GREM1,TOMM40,LRRC4B,MPHOSPH6,FABP4,COX4I1,ANAPC4,ARPP19,GDPD3,HDAC3,NLRP2,MRPL53,GLRA2,RPL29,BHLHE40,MAP1S,BPIFB4,PI16,CARHSP1,NPC1L1,KLHL9,TIMM8A,RAD21,AKAP17A,RAP1B,C2CD2L,DNAJB4,TXNRD2,FITM1,LAT2,ACTR1A,COQ10B,POLR2G,AIFM1,SNX14,CAMSAP2,FAH,ACVR1B,RPL10A,CTDSP2,SDC2,COX16,CUL3,OR5A2,ARMCX3,PLSCR3,CPLX1,POLR3GL,COX6A2,MAD2L2,TMPO,UBTD1,RBBP4,ABCB9,ATF1,FAS,GRB10,PIGY,SKA1,CSNK1E,CHMP2B,PAK6,ELOVL4,EIF3D,DNAJC4,RBP5,POLD4,MAN1A2,AKT3,ERVFRD-1,CCDC92,OR10Q1,KBTBD13,YIF1A,CA8,SMYD3,DDIT4,RAB3A,CTNND1,FAM91A1,LCN12,KPNA2,LGALS3,NMBR,LUC7L3,HHIP,MAP4,ORMDL3,FOXJ3,UFM1,USP30,RAD23B,CHN2,TMEM60,AIF1,CALU,HBEGF,EGR2,LRRC20,HAX1,RPS3,OR1F1,IL7,ZHX3,ATP6V1E2,PID1,SH3BGRL,ATXN1L,EXOSC3,SRSF4,NECAP2,GINS3,MYL12B,ENHO,APPBP2,CLEC7A,OPTN,GPR146,KCTD11,ARPC2,KRT222,CNTFR,SMNDC1,NEURL2,PDP2,POLR2D,SNX12,DRG1,FGF3,SRPRB,ERLEC1,CEP85,SNX33,TMEM42,NDP,SDCBP,USP13,MED23,NTNG2,ETFB,VIP,LRRC8D,WNT10B,HMX1,DGCR6L,FBXO11,SPSB1,RBBP9,ZNF688,RGMB,SPINT2,TMEM45B,BCL2A1,HRH2,APTX,AP2A1,MIF,EEF1B2,ZNF189,RBM15B,ZNF22,TFDP2,C1D,ACTR3B,CCT8,TMBIM6,PABPC1L,LSM2,ADAMTS20,GFOD2,DUSP22,SOD3,MTMR2,ICAM1,PLCL1,FAM187B,GABRB3,MRPL49,YWHAH,CD83,DNAJC7,UQCRQ,KCTD12,RPL12,PPME1,HSD17B11,ZNF652,ZNF177,C1QTNF1,AUH,IDE,ZNF267,TFRC,TTC8,IPCEF1,GGPS1,MND1,TSPAN11,SH2D5,OR1S1,HMGA1,UTP6,FOXI3,TXN,MAF1,CYB5D2,RPS12,DAG1,ZBED3,MTHFS,DUSP6,SETD7,PPIF,ZNF250,SERTAD3,OR10A7,EIF1B,MT3,GABARAPL2,PML,PSMA4,DNASE1L1,RDH12,TAX1BP3,ZNF790,TNFSF12,CALY,GABPB1,ARF4,SCGB1C1,KRTAP3-1,TAX1BP1,AP2M1,PRDX6,KIN,PPM1M,TP53,INMT,CRELD1,NFKBIL1,TRIM35,TRAFD1,PKIA,PPM1B,GADD45B,MGST2,SENP8,STX7,MZT2B,NECAP1,GPC4,LIMS2,OSGIN2,HBA1,TSEN34,FTSJ3,SYNDIG1,GSTM3,RWDD4,KPNA6,IRF8,TOX,PTRHD1,FCER1G,BET1,CYB561,SLC25A46,HSD17B1,TBC1D17,TMED4,HEXIM2,ZBTB16,ANAPC16,CHORDC1,BRMS1L,OR5B3,DHRS1,PAPOLA,FBXO34,HCST,IL12A,RHAG,OGDHL,CAPG,TLR1,SAR1B,CCR5,ACADS,PTGES,RNF128,PPP2R5A,GAPT,TLR7,VASH1,FTHL17,RALA,WDR55,ADK,G6PD,F11R,NAA15,SERPINB6,EXOC5,SYBU,EBLN2,CLSTN3,TBC1D19,RASL11A,CSTA,RGS6,TFPT,ELOVL6,ALOX5AP,PRDX4,SLC25A14,MECP2,ZNHIT1,NUP35,CRYL1,ORAI2,SERPIND1,CHST7,RPL24,ENO1,OLFM2,GNPTG,PHF21A,CAMP,RHBDL3,TRMT61A,SLC1A2,THNSL1,COX5A,CELA3B,GPD2,OMG,CYP11B2,LBR,FBXL7,STYK1,POP7,RNF181,RPRD1B,DCAF4L2,LYPLA2,TSPO,SNRPN,CERK,USP39,SLPI,ZNF174,USP38,LSM6,ZMAT5,RTP4,SYNGR1,PROX1,FGF13,PRKX,VPS4A,NAB1,ENPEP,SFTPD,CLEC12B,OAZ2,CTNNB1,RAB8B,INTS12,SOCS2,CYP2D6,ESR2,DCAF5,CWF19L1,CDK6,ADCY3,FAM13B,SNRPD2,SIRT7,IQSEC1,NOL4,FYTTD1,TAPBPL,RRAGA,ETV6,ABHD16B,RAP2B,TNFAIP3,ZBTB42,TRAF7,MMACHC,DUOXA2,MTMR12,ZNF805,HPCA,SV2B,SOST,TCP11L1,EIF4EBP2,OR2A2,SIVA1,GFOD1,EMC4,GPR37L1,NDUFAF2,SNAPC1,SNTA1,SPRED1,H19,ALDH1L1,MAK16,TSSC4,NONO,POLL,CYC1,POU1F1,NPTN,FCAR,CCDC42,ENTPD4,ARMC8,SLC35A2,ID1,PTDSS1,DEGS1,CRYBA2,ING5,INPPL1,KIF2A,MIA2,BACH1,NFE2L1,SPATS2L,NOP58,AKR1A1,MRPS25,RBCK1,COA4,PGAP2,CTSD,FABP5,MRGPRX4,SPEF1,SCAMP2,OR52M1,NUP107,DEK,NLGN2,CYP4F8,PRKD3,SLC5A6,CDKN3,BPGM,PPIB,CD164,ANP32B,CPT2,CHST9,NDNF,AP1G2,DCAF8L2,MTAP,RAB3C,PWP2,CETN3,URM1,CACYBP,CTSK,FAM200A,S100A10,NFYA,TOLLIP,BATF,TGFB1I1,DUSP1,STX8,MPHOSPH10,TMEM33,S100PBP,MRPL47,AP3S2,KLF10,BMPR1A,FAF2,SCG2,ARHGAP21,RHCG,SPINK13,LCN6,SETD4,OTUD6B,ACOT13,TMED3,WFDC13,CCND1,RPGRIP1L,OR2W1,COX7A1,FBXO9,NEK7,UTS2R,MOB3C,SPOCK1,LASP1,PHKG1,FUT8,GTF2A1,WBP2,SH3GLB2,EIF2B5,GALE,OSR2,CXXC5,ANKIB1,CIRBP,ENDOD1,OR51S1,ZSCAN1,WDR37,EIF4EBP3,PSMD6,IL23A,FURIN,SLC39A9,DHX9,AQP4,CREBL2,TXNIP,GNMT,CCL25,GLE1,RANGRF,NUDT19,THOC1,ABCC5,ATP2C1,FATE1,DNAL4,RC3H2,UBXN10,NUBP2,LDHA,PFDN6,SLC20A2,PCDHA5,GSK3A,PRCC,RNF187,APOBEC3C,GPR162,TXNRD3,ZMYND11,ZNF513,SLC7A4,EFHC1,SLC25A32,GJA10,THRAP3,EEF2,KIAA0040,EXOC2,XPO1,SURF4,INTS10,XPO5,CREB3,RNF103,TF,OXNAD1,TMED1,RBM23,BRI3,HEXA,OCEL1,ADAT1,CDKL2,KIF1C,CHRNA7,GAS8,BRMS1,PAOX,CD3G,SPATA2L,TBCE,IPP,NQO1,OPA3,TAC1,LMBR1L,AKR1C2,NPVF,IGFBP4,LPXN,RASGRP2,ST13,IL34,DFFA,RABAC1,WWP2,RAP1A,UCKL1,ACAA2,POLR2I,CD2,TIGD7,FBXO30,PTCRA,TRMT6,FGF17,HBB,NEDD8,CXCR1,KCND2,NDUFA5,CCL21,MSX2,RPRML,SNAI3,PELI3,CDC37L1,NLE1,KRR1,NDUFB8,APH1A,ISYNA1,NAA11,EIF1AD,XPOT,PDIA3,FRA10AC1,CXCL1,WNT7A,STX17,LEPR,LEAP2,HADHA,TRA2B,SOX21,RAB4A,DHX16,GXYLT1,NUDT16,OR6M1,LHFPL1,HSPB1,KCNA2,B4GALT6,ZKSCAN1,CLDN14,HSPE1,PGBD2,STAMBPL1,SIPA1L1,SERPINH1,RPL37A,SUPT7L,P4HA2,JOSD1,KIT,RS1,OR4D9,AFTPH,LSM3,GRSF1,RARRES2,PIWIL4,CSNK2A1,KPNA1,GNG7,CTNNBIP1,ATF4,KBTBD2,GSTO2,SLC7A9,HEBP1,PACSIN3,ALKBH4,MYH2,SNAP91,ROPN1B,VRK1,PGK1,DNAJC5,TMIGD1,CYP27A1,DYNC1I2,S100A6,LHX2,CDC73,ZYX,UBAP1,MMP9,BTF3,TMEM215,FBXO42,ZNF24,SERPINB10,TSEN54,WDR77,MTPN,MEST,FZD4,ATP6V1G1,MFSD6L,LYG2,AAMP,ZCCHC10,SYN3,MX2,TMEM213,GPBP1L1,NDST1,DNAL1,DHRS3,DEFB116,TNFAIP8L2,SMAP2,CDCA3,RAB3B,KTI12,AZGP1,HBE1,ABCB1,INO80C,FGF1,AZIN1,PSME2,MLF1,GTF2E2,MAGOH,CCL19,NKX3-2,TBC1D10C,JAK1,LBH,TRIM21,SIX5,ACTA2,ARMCX2,SPR,PPARG,ARFIP1,GALNT12,TRIM37,HECW1,ZBTB38,NFIL3,SETD5,HNRNPC,PTPN1,RMND5B,PGS1,SLC25A21,RBBP7,CLDN11,RABL2B,PAEP,NIPA2,FAM199X,TRAPPC1,RNASET2,SLC35E3,SPTAN1,LRP12,NPY2R,PKNOX1,ADRB1,ZDHHC14,RFX4,FRMD8,HEY2,RBM17,PCDHB8,FGFR1,HCRT,CAMK2N1,OR4K1,PYGM,SHC1,PEX3,FAM89B,RCVRN,CCDC127,CD200R1,KCNJ11,PPP3CA,CRYGB,PRMT2,CIB3,TACR3,BUD31,TMX4,SRP54,CAMK2G,SCFD1,TTC4,CCDC47,RPL15,TUBG1,CACNB4,GHITM,ARMCX5,ZNF593,PRPF4,AGER,CD58,IMPACT,RAB18,FKBP14,IDH2,PSMB5,MCOLN1,CCT5,ENPP4,SLC39A7,SBK2,SORD,FBXO32,ANAPC2,AGK,SMCP,SLC25A31,ZNF671,SLC17A5,MEAF6,UGCG,LIG3,RPS14,LYPLA1,EDF1,TMEM219,ATP6V0B,ZNF207,POLR3H,TMUB1,TRIM3,C1QC,E2F6,GPR89A,EFCAB7,EXOSC1,ZMPSTE24,GDI2,MRPL23,GFM2,RNF141,KLHDC8B,KLK9,PLA2G5,ARHGAP1,DOK4,PRIM2,SNRNP27,CD99L2,UBR7,PDIA6,SDR42E1,TRIM32,LYAR,UST,PFDN5,EXOC8,TOM1L2,GNRHR2,CNP,RND3,B9D1,NUDT3,GSTO1,TMEM156,SPRN,CCDC69,PSMA3,SOCS5,AK2,GALNT1,MDM2,MGP,EHBP1,MRPL13,FIBIN,SNX20,WDR38,L1CAM,TLR9,COMTD1,FNDC8,AKT1,DLX1,FGD2,APEH,PRRC2A,DPP10,RPS23,CRABP2,IL20RB,DKK3,SF3B4,PPIL4,RAB11A,ASMT,CCNI,CDO1,LRRC69,SWAP70,MYL12A,CYP39A1,HSD11B1,NCR3,ITK,EIF4H,FAM8A1,CHDH,GNRH2,SENP5,GRM2,CTNNBL1,CYP11B1,PYDC2,IDH3B,GALNT4,TLR3,ADGB,JAKMIP1,GPAA1,SLC38A9,OSM,IL15RA,RMND1,FAM78A,PPP1R2,MIOS,RAG1,ENY2,SLC35A1,DHRS4,HSBP1,MEF2A,IMMP2L,ZNF304,MRPL50,MRPL24,KLK3,SLC30A5,SNAPIN,LTBR,CASK,OR4D11,GAL3ST1,GABARAP,FGFR1OP2,TCP11L2,GRPEL1,ELMO1,PRPSAP1,ARMCX1,UBE2A,ATP6V0E1,UBE2D3,CCT2,CHRM4,P2RY1,ING1,STRBP,OR8B8,IRF1,NHP2,NAIF1,TRIM23,TAAR1,ZMYND19,SLAMF9,CCR6,ZNF397,APOBEC3A,ZNF319,SEC14L1,ID4,XAGE5,CNIH4,GLUL,NRP1,NCKAP1,CDK5R1,CLU,ATPAF2,KIAA0232,LMO4,NKX3-1,PGPEP1,F9,OPRK1,GCNT3,MYO6,ZNF740,CYP2C18,NDUFS8,GPR137,APOO,SNX17,BCS1L,SRRM5,TMEM144,TOP1,NRSN2,TMX3,HTR5A,EIF2B3,DNAJC22,GBE1,CHGA,TCF23,PAPSS2,GPR65,TEX30,SEC61B,BCL7B,TOM1,GPHN,ISG20L2,HSP90AB1,POLE4,CSRNP1,ZNF862,ATG4A,SYP,FUNDC2,MRPS23,FCN2,RER1,SFRP4,CDKN2AIP,RGS7BP,DSTYK,ZBTB5,AIF1L,CCR2,ZC3H7A,TMEM123,CIDEB,ATAT1,ARMC7,IPO8,TMSB10,VAMP5,METTL14,GNG2,EDEM1,GTF2H2,MBL2,MAP3K11,AMIGO1,JPH4,TOR2A,PTS,RMI2,COL1A2,SLC35D1,SMU1,R3HCC1,CSGALNACT1,SAT1,TFCP2,METTL2A,ABHD6,CLDN1,FAM162A,CCNB1,CTDSP1,NDUFAF4,CRYBB2,AKAP14,ALKBH5,ERH,ANKRA2,ADIPOQ,IK,UHMK1,CRTAP,LCP2,TRIM54,CDC42SE2,FAM98A,ACBD7,RPLP2,GREM2,TGIF2,GPX6,POPDC2,OR4Q3,HTR1F,RDH10,CREBBP,PRPF19,GPAM,LDOC1,PDCD4,GTF2B,CXCL3,SDF2L1,RUVBL1,GIT2,OAS1,NKIRAS1,SLC13A5,LAMB2,CLDN4,RAB3D,ZNF287,KDM4B,TMEM184B,ACAT1,TMEM114,CDK4,NPR2,DPY30,CNNM4,NR1I2,ABHD4,PCDHB1,BRCA1,KCNK13,TRAF2,RBM7,PDHA1,ADPRH,KCNMA1,BCL10,NOS1AP,MBD5,STMN2,RGS2,DUSP19,NME1,FKTN,KLK6,TMED7,DNAJC3,RNASEH1,SERINC3,SLC41A3,STAU1,TSN,STOML3,CD36,IRF3,MTHFD2L,STOX2,PCMTD2,STXBP1,PAX9,KLC2,ERV3-1,PRKAB1,UQCRH,DPEP1,IL18,DERL1,SOX2,CSNK1A1L,ST3GAL1,FAM163B,SLC32A1,PARP11,IFRD2,CEP97,ZNF501,POR,ST3GAL5,LCA5,STK24,RAC2,NDUFB4,TAS2R40,LRP6,PYROXD2,MRPS21,SNCG,BLOC1S2,SNAPC3,RAB40AL,DDX39A,SSU72,IGBP1,AKAP12,EIF4E,TRIM5,TMSB4X,CDKN2C,COX4I2,LHFPL4,CALHM3,NAT2,KHDC1,SPECC1L,OR10G9,TSPAN5,BZW2,RINT1,FABP7,BCAP29,ZBTB17,EIF3K,B3GALNT1,CREB3L4,CD274,PHYH,FUT9,ADIG,HOXD12,NTN4,RTKN,RPLP0,IL10,UBE2V2,SH3GLB1,PREPL,THTPA,EFNB1,RNF113A,GOLGA7B,OLFML3,TSPO2,COMMD8,PELP1,ITGA6,CSNK1A1,DEFB114,MT1M,IFNA10,TFE3,EMP3,OSTM1,CHMP2A,CBR4,SLC19A2,VMP1,HSPA8,MSMP,GMPPB,CALHM2,ADO,TES,CCDC25,FAM219B,BECN1,LMNB1,EED,ABHD14B,MRPS16,CIB2,TGFB3,ACSL4,TRIM24,MRFAP1L1,DTYMK,ELP3,YAF2,ZNF592,MTRF1,EWSR1,B9D2,GPX3,PROS1,TMEM204,EIF4B,SMAD3,MRTO4,PTHLH,SLC25A4,PPP2R1A,MLF2,PLEKHJ1,ELMOD1,DERL2,TXNL1,TIMP1,TMEM59,IL6ST,RPL23A,LYNX1,SLC6A11,RAB37,FOLR1,CAV2,C1QL1,CSTF2T,FBXO25,IFI35,PSRC1,TIMM10,SELENOK,STK38,SMN1,AP1AR,WEE2,PNP,RAB5C,PCDH19,SNRPA,CMPK1,BEND5,GPIHBP1,WDR44,RAB2A,CTNNA1,VAMP2,CCNF,TRAPPC6B,CRBN,VPS33A,SACM1L,CD226,B4GALT3,ZFP1,PDYN,KCNIP3,INPP4A,FGFBP2,EZH2,ARCN1,RAB9B,AMT,DYRK1B,FN3KRP,WIF1,PHYHIP,STAT6,ISG15,SNX24,ACADSB,OR10G7,MRGPRX2,FLYWCH2,GRIA2,LRRC24,CAB39,LIX1,KLK5,DDX4,TMEM91,CASP12,ZCCHC9,SLC43A2,TOP3B,B3GNT2,HIGD2A,TEX12,TAF5L,PNPLA8,MYEF2,GLT8D1,UQCR11,NGB,MOV10,TRIQK,GPX5,PCGF3,TMEM14A,TCEAL7,GDE1,CDH8,CPSF2,OR14J1,SLITRK2,STX18,ORAI3,ELSPBP1,GK2,CDKN1A,FOXN2,RBFOX2,PPFIA3,OTUD7B,CLIC2,MED11,SDHAF2,AKIP1,PIWIL2,SOS2,ROGDI,PGM2L1,GYS1,SLC23A2,FAM168A,ACTL6B,SLC4A8,SNIP1,UBE2D1,LY6G5C,HRH3,ABHD13,ZBTB45,OR5L1,INHA,RGS5,RPAP2,RAB1B,NDE1,RBMX2,AMY2B,SELENOV,CCDC65,LDHAL6B,TDRD7,CD2BP2,HMBS,ZNF576,RABL3,UPF3B,ISCA2,GCA,TRAM2,PPP1CB,EHD1,CHST1,FCHO2,MPV17,RFXANK,SESN2,PLAGL1,PAPOLB,TRAM1L1,KLHL15,FOXS1,PTRH2,TMEM203,TAS2R5,OR4F6,CRYBB3,ACTR2,TMEM164,ACP6,SYNJ2BP,APLN,SELENOS,TMCC2,ZNF609,SLCO1A2,KCNK10,TMEM106C,SRP14,NUS1,GJB2,WDR3,MANSC1,KRT7,PLEKHA8,CDH13,NPY5R,CXCR4,HSPA14,PGR,HAND2,LCN9,BRD9,POLR3B,KCNH1,OR2H2,PAFAH1B2,DLG4,GTF2F2,KIAA1191,CCL17,SERPINA5,CREB1,BICD2,NAPG,RNF122,KIAA0408,SQSTM1,GLIPR1,RAN,RPP25,RBM12,TMEM177,FMO2,ADAMTS1,CXCL14,CLDN8,SPRR1B,RPL6,TUSC3,BNIP3L,DDX42,SLC7A14,GMPPA,CYB561D2,ATP1A2,PXMP2,PPP1R16A,MT2A,DYRK2,FOS,CLDN22,EGLN3,MRPS28,RIOK2,OAT,RPL26,OS9,POMP,NFKB1,HNRNPK,PAFAH1B3,PRKAG1,LHFPL2,MAFG,SCD5,ACAP2,HNRNPA2B1,TAPBP,ATP6V1C1,GGCT,RCBTB1,PLA2G15,FANCG,STX6,OR2A25,MAPK1IP1L,RB1CC1,SLC35E1,CAPZA2,TPPP,RFTN2,CCL8,NAA60,PPID,ABRACL,YPEL5,SUMO3,OPHN1,CCR3,ZNF687,OGG1,SFT2D2,RAB23,CMAS,PTGER1,RHOJ,CBLN4,WWP1,JUN,IFNG,TMEM50B,HIRA,S100A8,CD47,SPTBN1,TNRC6C,UTP23,EIF3J,FERMT2,TOMM40L,GIMAP2,GNPNAT1,RNASEL,CHI3L1,TNFSF18,PPDPF,DNAJC8,CRYGD,RAB33A,FAM107A,RNF167 |
| 1.028e-10 | -23.00 | MRPL42 (mitochondrial ribosomal protein L42) | protein interactions | 28977 | 240 | 114 | 19454 | 5460 |
MRPL50,ALCAM,MRPL24,MALSU1,SSBP1,MRPS9,PRR3,TMEM70,CHCHD1,OSBPL8,GRSF1,EDC3,VRK1,CSE1L,RPL17,RIGI,MRPL22,FASTKD5,SFXN1,MRPL52,PPP1R12A,MRPL36,MRPL49,MRPL51,MRPL33,GFM2,MRPL47,MRPL11,ATP5PB,METTL15,EEF1A1,ROMO1,IDE,EIF2AK2,CYRIB,MRPL53,MRPS28,PTPN11,TUFM,MRPL41,MRPL40,GTF2I,MRPL17,MRPL20,ARFIP1,GFM1,ARPC2,PGK1,IDH2,MTRES1,ZNF574,OXSR1,PPP1R8,SF3A1,RBMS2,MRPL10,SNX1,SNX2,KCTD10,HNRNPL,GATD3,FAHD1,MRPL18,RHOG,MRPS26,RPL6,MRPS35,SYNJ2BP,MTRF1,MRPL9,GNL1,H1-6,KRAS,LSM14A,HSPD1,COX8A,SRSF7,HINT2,PTRH2,PDHA1,CYB5B,HGS,SUPT5H,RBM12,NAA15,RPL35,MRPL23,RPL19,APEX1,TACO1,MRPL13,GTF2F1,PAPOLA,PMPCA,HNRNPC,AUH,MYC,NIBAN2,MRPL16,TOMM40,MCMBP,MRPL57,EXD2,NGRN,STK26,LCN1,TTC1,MRPL34,ADSS2,MED23,MRPS18A,KLC2,RPL27A,MRPL12 |
| 1.118e-10 | -22.91 | CCT7 (chaperonin containing TCP1 subunit 7) | protein interactions | 10574 | 541 | 220 | 19454 | 5460 |
UCHL3,PPP2R2C,THOC3,FBXW4,WBP2,PSMA3,ANXA7,WDR77,ACTL6A,CDKN1A,MTM1,PRDX2,ACTB,TUBB,BTG3,GNB1,LRRC28,ATP1A3,BRCA1,DCAF4,PFDN4,PFDN2,RIT1,ILK,KLHDC8B,CUL3,RNF40,G3BP1,RBBP7,PCGF6,RAD21,HECTD3,RPS24,RPN1,EZH2,NME1,POLR2C,GNB1L,B3GNT2,RAF1,MAPK10,WDR37,EGLN3,CETN2,CEP19,DNM2,PPP2CB,PHB1,IGBP1,SKIC8,PPM1B,DCAF11,PPP3CA,BCL2L1,IRF7,RPA3,SOD1,PRPF4,FLCN,ANAPC16,SQSTM1,CDK1,METTL14,PDCL,ATG16L1,WDR83,WDR5B,CCND1,CEBPE,NDN,ARMC6,PDCD5,VIRMA,STUB1,CCNF,TUBA1B,METAP2,ENO1,SMAP2,ZBTB18,PPM1M,UBASH3B,STK24,CIAO1,HUWE1,ANAPC11,DNAAF10,DUSP21,FBXO25,FAF1,GLUL,HAPSTR1,HSD17B10,MMACHC,ACTR2,PPP4C,CCT5,ZBTB2,EEF1AKMT3,METTL6,PSMB1,TES,SSX2IP,FGR,FNDC11,MOV10,HDAC6,SUV39H1,EMC1,UFL1,EEF1G,DDX39B,HDAC5,P4HA2,HSPA8,DDX5,THBS3,PPT1,EIF4B,PIH1D1,PACRG,MED31,PTAR1,FBXO42,CBX5,APEX1,ESR2,DES,DLST,ANAPC2,CCT2,PLA2G15,PELI3,PSMD14,COP1,CRMP1,APOBEC3B,MYC,PSMA4,KLHDC8A,BAG3,KRAS,PSMA2,PFDN1,CCT8,CDK5,ACTR1B,TUBB4B,DCAF8L2,MOB3C,RHOBTB1,HEXA,TUBA1A,SOX2,DYNC1I2,TCP1,TRMT61A,NKX3-1,EED,WDR82,DCAF5,AGR2,ASB7,MAPK4,PFDN5,DDRGK1,ACTR3B,HDAC3,WDR55,BCL6,BAP1,HCFC2,NLE1,WRAP53,TRIM68,RPA2,SAMM50,UBE2M,HEXIM1,HECTD1,GABRA1,BUB3,MAP3K3,KCTD9,SMURF1,CDC20,UQCRC2,CREB1,MOB4,RAP2C,RC3H2,ATP1A1,ANAPC4,DTL,UBE2H,AKT1,PTPN11,DYNC1I1,ATP1A2,CDC40,KDM4B,RASL10B,MEPCE,DUSP19,STRADB,METTL18,MAP1B,PSME1,TP53,ACTR1A,FZR1,SPPL3,MIOS,MBD5,CDC5L,CD274,RAP1B,TUBG1,B9D1,GAPDH |
| 1.129e-10 | -22.90 | brain | COSMIC cancer mutations | brain | 16146 | 4710 | 16828 | 4835 |
DHPS,RRN3,UTS2,GNG5,TMEM14B,NIF3L1,CYP27B1,PNOC,NTPCR,YBEY,MRPL10,IL15,ARL6IP6,TLE1,BTF3L4,HMG20A,RIMS4,NDUFA2,IFNGR1,NUP50,MOG,PLSCR4,LRRC57,SCN3B,NMI,OSGEP,PADI2,POLR2F,POMT2,NDUFB10,NSFL1C,TMEM190,OGN,SCPEP1,RIC3,DES,ARHGAP25,ZRANB2,PCDH9,LIN7B,MYOZ3,EIF4E3,TCAP,VTI1B,GLT8D2,SPATA6,ZNF575,MRPS7,CCL20,ARHGAP5,RPL35A,RSRC1,ZNF668,CD248,KLHL12,PPM1D,IDO1,SERPINI1,SLC39A3,SLC25A28,CXCL12,MSL2,FLCN,GRPEL2,STIM1,TMC7,LRIF1,FTL,TNFSF13,FLRT3,HMX2,CHST11,MTMR6,NEUROG2,CCDC85B,SEMA6C,LUM,ICAM3,UNC50,MED31,SH3BP5L,RPL7,TUBA1A,YTHDF1,CELF6,NAA50,FCGR2A,ENTPD3,RASGRP3,MGAT1,RCE1,RGS19,IFIT2,RAB33B,SECISBP2L,MCM3,RNF115,CDC42EP3,SLC25A11,PAFAH1B1,KCTD15,MS4A7,PDCD1,HNRNPD,PSMD12,CCT7,CKLF,NLRP6,CHRDL1,ZCCHC17,PSMB6,PEG10,IZUMO1,PIP5K1A,TRAF3IP2,TOMM20,PTGER4,DHRS7B,BAHD1,TERT,CISD1,MORC4,PIK3R3,LANCL1,MKKS,SLC35B4,KRTAP12-4,MPZ,VPS28,SRC,CD2AP,RASL10A,METTL6,GNG13,OR51M1,TUFM,IDH1,IFNA2,PDRG1,FOLR2,SOCS3,PTPN22,CD1A,HSP90AA1,LPAR1,HDDC2,FNDC9,PPIH,DCUN1D5,EPO,EID1,MMP21,ZNF280B,NFKBIB,CHCHD3,RNF121,PGAM1,AP2S1,UGDH,RPS13,ACTB,DDAH2,MATN4,CPNE1,GNB4,CNTN1,ZER1,RFC2,LNX2,TYW3,SNX18,TAS1R2,DAD1,ZBTB2,MFN1,PLA2G12A,CAMLG,SLAIN2,NPY,CNR1,GABRA2,PFDN4,COMMD5,SST,TMEM208,NICN1,RSAD2,RAB30,EFHD2,PSMA2,DNAJB2,GGT7,GRXCR1,NAA35,GSTM2,UBFD1,PPIG,NRBF2,PPP4C,DYNC1I1,HECTD1,LGR4,FGF10,TLR2,IL6,PPP1R12A,CCDC122,GRID1,RERE,ARMC1,GABRB2,TFEB,CES5A,HSCB,SYVN1,RPAIN,UNC119B,TBC1D4,MORN4,GIMAP4,HPGDS,NDUFS3,OR9K2,RLN2,GOLGA5,OSBP,DNTT,PSMC1,MED21,OCIAD2,TWSG1,PAIP1,SSRP1,TTC32,FAU,CLVS1,PSME1,CYP2F1,PNO1,KBTBD4,SMC4,OR8I2,GTF2E1,TNNC2,AK5,RAB22A,OR5AP2,ELAVL2,MOSPD1,ISCU,FCHSD2,AGAP1,UBE2E3,TRIM10,SLC6A12,PIR,UBE2M,RPF1,LDHB,RNF126,TMEM182,FOXP4,AKR7A2,AURKAIP1,FXR2,TCEANC2,TM9SF4,LRRC1,NUP37,FERD3L,USP5,MXI1,ITGAV,GPBAR1,PPP2R3A,GPR85,SLC1A3,SLC22A8,SMAD4,DRD1,RILPL2,FZR1,IL1RAP,VKORC1L1,DRAM1,CNPY4,SMARCA5,FAIM,ELK4,ATP1B1,BAK1,PHAX,FKBP10,BAALC,GPX4,EXOC1,RIMKLA,SEC62,FGF12,RHCE,LY6G6C,TMEM106A,ANGPTL2,TNNT2,GOLPH3L,TESK2,COMT,STK11,SEC61A2,RPS27L,ELAVL4,SNRPD3,ZNF175,LAMTOR3,TP53INP2,GPSM3,LITAF,ARFGAP3,ARL4A,MEF2C,DRAP1,LRRC4,RPRM,PLAA,BAP1,DOHH,FUT1,SYS1,IL1B,GPR26,COG1,RPL10L,SCYL2,MBLAC2,ALG2,PHKA1,SAT2,PRRG1,GPNMB,RAF1,IRF6,RGMA,DNAJC10,OR51A4,ZNF330,DET1,MCHR2,KLHL7,CSTB,GTF3C3,RNF14,EIF4A3,DDX5,RAP2C,LAMTOR1,ADNP,CYP17A1,FOXP2,UBE2F,TPSG1,UBN1,CYTH1,CCDC71,SLC1A1,PDE9A,RPS5,CCHCR1,SLC22A12,SNAPC2,EGFL8,ARL15,ILVBL,AZI2,NUDT5,NDUFA12,KCNMB2,GTPBP1,RPS11,NAE1,GSTK1,KATNAL1,TXNRD1,TNFRSF14,TMOD1,TMEM199,GZMK,FBP1,STX12,CENPP,RP2,NLRP1,CNPPD1,PSMA5,AOX1,STARD13,B4GALT1,ATP1A1,CRKL,TGIF2LX,DNAJC27,LRRN1,CD1B,GCC1,KDSR,ZFAND2B,DNAJB6,TMEM209,GLYAT,GFI1,PLN,CD1D,MYD88,MRPL52,FCF1,E2F4,PPM1G,CDC42EP2,BOLA3,DEDD,FLRT2,CSNK2B,YIPF4,OR4K17,TMUB2,RHOB,MAX,HOXB1,NRSN1,G2E3,GLRA1,MTG1,RPL3,TOPBP1,QPCTL,RBM18,PROM1,C1QL3,VMO1,MRPS18A,TRIM11,GNAI2,CDC123,UCK1,TRMT1L,KCNMB1,CD46,GABARAPL1,FAM118B,ARL10,MYCT1,CBX5,PEX5L,COMMD2,TM9SF1,MAGOHB,RRAS2,ATL1,SNCB,TPT1,RERG,FRS3,POLR3F,RPL35,RNF20,COPS7A,PPARA,GPR15,OTUD6A,STOML2,TOR1AIP2,NUP153,MICB,GTF2A2,ACTL9,EYA3,DUSP26,RNF39,PBLD,HDAC6,TMEM176A,ANAPC13,CNTNAP1,AGPAT1,BTG1,EIF2S2,ZMYM4,CHMP5,ASB3,USP14,NANP,TSC22D3,TXNL4A,CISH,GNA14,CXCR6,SPOPL,SYT2,LEPROTL1,TMEM95,PRPF31,NR1H2,BMP1,MMADHC,TTC1,PHB2,EDNRA,ST6GALNAC3,TBC1D24,SLC25A44,ZNF692,TESC,THY1,YWHAB,PSMD14,SESN3,CDSN,LRWD1,ARRDC3,ZCCHC12,NFYB,SLC25A17,LILRA1,PDE1A,DAPK1,KCNQ5,TPBG,STXBP6,MAP1LC3A,SELENOF,RAB13,OR10G2,RNF26,PATE2,MRPL51,CDK5,GNG3,CYB5R3,PLAC8,NDC80,RPP21,SNAPC5,SFTPC,ZC3H15,DSN1,ODC1,SLC25A23,NME4,FNTB,TOB2,YIPF5,PDSS2,SLC6A4,OAF,SHMT1,SLC45A3,CYTL1,NDUFA4,PPFIBP1,SYNGR4,HEXB,CALR,TRUB1,SNAI2,THBS3,DRG2,PKIG,MOBP,ADCY2,TSG101,MAMDC2,PAX6,ZNF507,STAT1,DPP4,PRDX2,EIF2S1,UGP2,LMO3,LMBRD2,MRPS33,IL3,MSX1,CHRM1,KCTD9,RPN1,CD151,TLR6,P2RY11,DLG1,SDC4,CD79B,WASL,DYNLT3,ZBED4,OR4N4,SP4,BVES,RAB14,TMCC1,REP15,GOLGA7,NDUFB7,ZNF526,NDUFV2,NEK2,APOBEC3D,PC,RAB5A,TMEM31,PTN,SSBP1,KCNA3,F10,CHCHD1,ARMC6,SIKE1,NDN,TBC1D5,CLRN1,DBH,SNX3,GOSR1,IGF2BP1,RUVBL2,NCOA5,MMAA,PPIC,LPAR6,GNAQ,POLR2C,NFE2L2,GIPC3,DBNDD1,RAD1,NGRN,CCDC167,SMAD2,USP46,PITPNB,CD80,IREB2,HNRNPL,UBTD2,PKIB,EMX1,TAF11,CNOT7,ADRM1,RABIF,CH25H,OR2F1,HPS6,KCNH8,TCP1,CRMP1,CDC5L,LGI1,SLC35A5,TMEM19,PSKH1,FKBP4,STX16,SMURF1,PI3,EIF5A2,PMP2,DPPA2,ANO3,UBE2N,PRR19,CTRB2,NGDN,CCL1,PFDN1,LIN7C,SSR3,ANXA7,NCSTN,SGMS2,TAF2,NKX6-2,P2RY10,GPR22,PLAC9,SLC38A2,HS3ST5,ADRB2,SLC6A1,TLR4,GPN2,GPT,SRSF12,QSER1,MYO1B,SLC2A1,PAK1IP1,COL3A1,CBX7,VAMP1,GLYATL3,PEBP1,ADRA1A,TNNI1,CX3CL1,FGF22,PSMB2,VDR,CTTNBP2NL,PTGDS,IL5,CYP7A1,ABCE1,PRRT1,GINS4,DIRAS1,SDS,DCK,ADH1A,EAF2,ITM2A,NUDT4,RPS24,MCM6,DCUN1D1,DEFB129,SPOP,CYB5R4,TRIM22,AMACR,NR0B1,MRPL36,SASH3,TPRA1,TIFA,B2M,SLC52A3,SLC15A2,CASP4,ACVR1,DCTN6,VDAC2,IFT57,MYH1,LYZL4,PLEKHO2,SCAMP5,CST3,ICA1,YWHAG,BCL2L1,TNFRSF9,KCNB1,NOP16,ZNF32,DMAP1,LRRC8C,PPP1CC,PAQR8,OR4E2,BAZ1B,PEX26,OR7D4,CFDP1,DUSP9,SIGMAR1,IFNK,ATP2B4,CXCL9,MRPL17,RBPJ,UQCRC2,MRPL33,RNF152,LRRTM1,EGLN2,EDEM3,TPPP2,KLHL28,LRAT,ISOC1,EDDM3B,ZDHHC8,MCPH1,NKRF,RETN,PSMB11,HSP90B1,TCOF1,ASB1,RPS15,VIPR1,QRSL1,FBXL3,RGS10,PTGES3,GATAD1,ACTN4,NEO1,PCCB,HSD17B3,ESAM,NXT1,SLC35C1,ANKRD50,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SG20L2,HSP90AB1,POLE4,ZNF862,ATG4A,SYP,CSRNP1,FUNDC2,MRPS23,RER1,FCN2,CDKN2AIP,RGS7BP,SFRP4,HTR5A,TMX3,EIF2B3,DNAJC22,CHGA,PAPSS2,TCF23,GPR65,SEC61B,TEX30,TOM1,BCL7B,PGPEP1,F9,NKX3-1,OPRK1,GCNT3,MYO6,CYP2C18,NDUFS8,GPR137,SNX17,BCS1L,APOO,TOP1,TMEM144,NRSN2,RUVBL1,SDF2L1,GTF2B,CXCL3,NKIRAS1,OAS1,GIT2,CLDN4,SLC13A5,LAMB2,RAB3D,ZNF287,TMEM184B,KDM4B,ACAT1,TRIM54,FAM98A,ACBD7,CDC42SE2,RPLP2,TGIF2,GREM2,POPDC2,GPX6,HTR1F,OR4Q3,CREBBP,PRPF19,LDOC1,PDCD4,GPAM,RDH10,TFCP2,METTL2A,ABHD6,CLDN1,CCNB1,CTDSP1,FAM162A,AKAP14,NDUFAF4,CRYBB2,ALKBH5,ERH,ANKRA2,ADIPOQ,LCP2,CRTAP,UHMK1,EDEM1,GNG2,VAMP5,METTL14,GTF2H2,MAP3K11,MBL2,TOR2A,PTS,AMIGO1,JPH4,COL1A2,RMI2,SMU1,SLC35D1,R3HCC1,CSGALNACT1,SAT1,SLC32A1,PARP11,CEP97,ZNF501,IFRD2,ST3GAL5,POR,STK24,LCA5,RAC2,LRP6,TAS2R40,MRPS21,PYROXD2,CD36,MTHFD2L,IRF3,PCMTD2,STOX2,PAX9,STXBP1,KLC2,PRKAB1,UQCRH,DPEP1,DERL1,IL18,SOX2,CSNK1A1L,ST3GAL1,TMED7,DNAJC3,RNASEH1,FKTN,KLK6,SERINC3,SLC41A3,STAU1,TSN,STOML3,NPR2,CDK4,CNNM4,NR1I2,DPY30,BRCA1,ABHD4,PCDHB1,KCNK13,TRAF2,RBM7,PDHA1,ADPRH,MBD5,KCNMA1,NOS1AP,BCL10,RGS2,STMN2,NME1,DUSP19,EED,ABHD14B,MRPS16,ELP3,YAF2,CIB2,TGFB3,ACSL4,MRFAP1L1,TRIM24,ZNF592,MTRF1,B9D2,EWSR1,PROS1,GPX3,TMEM204,EMP3,OSTM1,CHMP2A,SLC19A2,CBR4,VMP1,HSPA8,GMPPB,CALHM2,ADO,TES,CCDC25,BECN1,LMNB1,PHYH,FUT9,RTKN,NTN4,HOXD12,RPLP0,UBE2V2,IL10,EFNB1,RNF113A,THTPA,SH3GLB1,PREPL,OLFML3,TSPO2,GOLGA7B,PELP1,CSNK1A1,ITGA6,COMMD8,TFE3,MT1M,DEFB114,IFNA10,SNAPC3,SNCG,BLOC1S2,SSU72,AKAP12,IGBP1,RAB40AL,DDX39A,TMSB4X,TRIM5,EIF4E,LHFPL4,CALHM3,CDKN2C,COX4I2,SPECC1L,NAT2,KHDC1,RINT1,TSPAN5,OR10G9,BZW2,BCAP29,ZBTB17,FABP7,CD274,EIF3K,B3GALNT1,CREB3L4,KCNIP3,INPP4A,EZH2,ARCN1,FGFBP2,RAB9B,AMT,FN3KRP,WIF1,DYRK1B,PHYHIP,STAT6,OR10G7,ISG15,SNX24,ACADSB,BEND5,CMPK1,SNRPA,RAB2A,CTNNA1,GPIHBP1,WDR44,TRAPPC6B,VAMP2,CCNF,CRBN,CD226,SACM1L,VPS33A,B4GALT3,PDYN,ZFP1,RAB37,SLC6A11,FOLR1,CAV2,CSTF2T,PSRC1,IFI35,FBXO25,C1QL1,TIMM10,STK38,AP1AR,RAB5C,PNP,PCDH19,WEE2,EIF4B,MRTO4,PTHLH,SLC25A4,SMAD3,PPP2R1A,ELMOD1,MLF2,PLEKHJ1,TIMP1,TXNL1,DERL2,TMEM59,IL6ST,LYNX1,RPL23A,FAM168A,ACTL6B,UBE2D1,LY6G5C,SLC4A8,SNIP1,HRH3,ZBTB45,ABHD13,OR5L1,RGS5,RPAP2,INHA,RAB1B,NDE1,RBMX2,AMY2B,CCDC65,LDHAL6B,HMBS,CD2BP2,TDRD7,SLITRK2,ORAI3,STX18,ELSPBP1,FOXN2,RBFOX2,GK2,CDKN1A,PPFIA3,OTUD7B,SDHAF2,CLIC2,MED11,AKIP1,PIWIL2,SOS2,ROGDI,PGM2L1,GYS1,SLC23A2,TAF5L,PNPLA8,MYEF2,GLT8D1,UQCR11,NGB,MOV10,PCGF3,GPX5,TMEM14A,TCEAL7,GDE1,OR14J1,CDH8,CPSF2,MRGPRX2,LRRC24,GRIA2,FLYWCH2,KLK5,LIX1,CAB39,DDX4,TMEM91,SLC43A2,ZCCHC9,TOP3B,B3GNT2,HIGD2A,TEX12,CLDN8,ADAMTS1,CXCL14,TUSC3,SPRR1B,RPL6,BNIP3L,DDX42,SLC7A14,GMPPA,CYB561D2,PPP1R16A,MT2A,ATP1A2,PXMP2,HSPA14,CXCR4,NPY5R,POLR3B,HAND2,PGR,BRD9,KCNH1,KIAA1191,CCL17,PAFAH1B2,OR2H2,DLG4,GTF2F2,BICD2,SERPINA5,CREB1,RNF122,NAPG,KIAA0408,RPP25,RAN,RBM12,SQSTM1,GLIPR1,TMEM177,FMO2,CRYBB3,OR4F6,PTRH2,FOXS1,TAS2R5,TMEM203,ACTR2,SYNJ2BP,ACP6,TMEM164,APLN,TMCC2,ZNF609,KCNK10,SLCO1A2,SRP14,NUS1,TMEM106C,KRT7,PLEKHA8,WDR3,GJB2,MANSC1,UPF3B,ISCA2,RABL3,ZNF576,GCA,PPP1CB,TRAM2,FCHO2,CHST1,MPV17,EHD1,RFXANK,TRAM1L1,SESN2,PAPOLB,PLAGL1,KLHL15,TNRC6C,SPTBN1,EIF3J,TOMM40L,FERMT2,GIMAP2,GNPNAT1,UTP23,CHI3L1,RNASEL,TNFSF18,PPDPF,DNAJC8,RAB33A,CRYGD,FAM107A,RNF167,OPHN1,SUMO3,CCR3,ZNF687,OGG1,SFT2D2,RAB23,CMAS,PTGER1,CBLN4,RHOJ,WWP1,TMEM50B,IFNG,JUN,S100A8,HIRA,CD47,HNRNPA2B1,GGCT,RCBTB1,ATP6V1C1,STX6,FANCG,OR2A25,PLA2G15,MAPK1IP1L,TPPP,RFTN2,CAPZA2,SLC35E1,RB1CC1,CCL8,YPEL5,PPID,CLDN22,EGLN3,FOS,DYRK2,MRPS28,RIOK2,OAT,POMP,RPL26,OS9,NFKB1,PAFAH1B3,HNRNPK,PRKAG1,LHFPL2,ACAP2,MAFG,SCD5,SOST,TCP11L1,ZNF805,SV2B,HPCA,OR2A2,EIF4EBP2,EMC4,GFOD1,SIVA1,SNAPC1,SNTA1,NDUFAF2,GPR37L1,SPRED1,H19,MAK16,ALDH1L1,TSSC4,POLL,NONO,SIRT7,FYTTD1,IQSEC1,NOL4,TAPBPL,RRAGA,ETV6,RAP2B,ABHD16B,TNFAIP3,TRAF7,MMACHC,MTMR12,DUOXA2,SFTPD,CLEC12B,RAB8B,CTNNB1,CYP2D6,INTS12,SOCS2,ESR2,DCAF5,CWF19L1,CDK6,ADCY3,SNRPD2,FAM13B,SLPI,CERK,USP39,ZNF174,USP38,SYNGR1,LSM6,RTP4,ZMAT5,FGF13,PRKX,PROX1,VPS4A,ENPEP,NAB1,AP3S2,MPHOSPH10,MRPL47,S100PBP,TMEM33,KLF10,FAF2,BMPR1A,RHCG,ARHGAP21,SCG2,LCN6,SETD4,CCND1,RPGRIP1L,OR2W1,ACOT13,TMED3,WFDC13,COX7A1,FBXO9,ANP32B,CHST9,CPT2,DCAF8L2,NDNF,AP1G2,PWP2,MTAP,RAB3C,CACYBP,CTSK,CETN3,URM1,NFYA,FAM200A,S100A10,STX8,BATF,TOLLIP,TGFB1I1,DUSP1,SPATS2L,NOP58,AKR1A1,NFE2L1,RBCK1,MRPS25,PGAP2,CTSD,FABP5,MRGPRX4,SCAMP2,NUP107,OR52M1,SPEF1,PRKD3,CYP4F8,SLC5A6,DEK,NLGN2,PPIB,CDKN3,BPGM,CD164,NPTN,FCAR,CCDC42,CYC1,POU1F1,ID1,PTDSS1,ENTPD4,ARMC8,SLC35A2,DEGS1,CRYBA2,ING5,INPPL1,KIF2A,BACH1,MIA2,APOBEC3C,GPR162,RNF187,TXNRD3,ZMYND11,SLC7A4,ZNF513,THRAP3,EEF2,EFHC1,SLC25A32,GJA10,EXOC2,XPO1,XPO5,SURF4,INTS10,TF,CREB3,RNF103,RANGRF,NUDT19,THOC1,ABCC5,DNAL4,ATP2C1,FATE1,RC3H2,NUBP2,PFDN6,LDHA,UBXN10,SLC20A2,PCDHA5,GSK3A,PRCC,ZSCAN1,OR51S1,EIF4EBP3,WDR37,IL23A,PSMD6,DHX9,FURIN,SLC39A9,AQP4,TXNIP,CREBL2,CCL25,GNMT,GLE1,UTS2R,NEK7,SPOCK1,PHKG1,LASP1,MOB3C,FUT8,WBP2,GTF2A1,EIF2B5,SH3GLB2,GALE,OSR2,CXXC5,ENDOD1,ANKIB1,CIRBP,HADHA,LEAP2,DHX16,TRA2B,SOX21,RAB4A,OR6M1,NUDT16,GXYLT1,KCNA2,HSPB1,B4GALT6,LHFPL1,HSPE1,ZKSCAN1,CLDN14,STAMBPL1,SIPA1L1,PGBD2,SERPINH1,RPL37A,RPRML,MSX2,CDC37L1,PELI3,SNAI3,KRR1,NLE1,NAA11,EIF1AD,APH1A,NDUFB8,ISYNA1,CXCL1,XPOT,PDIA3,FRA10AC1,WNT7A,STX17,LEPR,ST13,LPXN,RASGRP2,DFFA,IL34,UCKL1,RAP1A,ACAA2,WWP2,RABAC1,FBXO30,TIGD7,POLR2I,CD2,TRMT6,PTCRA,NEDD8,CXCR1,HBB,FGF17,KCND2,CCL21,NDUFA5,OXNAD1,RBM23,TMED1,HEXA,ADAT1,OCEL1,BRI3,CDKL2,KIF1C,CHRNA7,GAS8,CD3G,BRMS1,PAOX,IPP,NQO1,SPATA2L,TBCE,OPA3,TAC1,LMBR1L,NPVF,IGFBP4,AKR1C2,NDST1,DEFB116,TNFAIP8L2,DHRS3,RAB3B,CDCA3,SMAP2,KTI12,FGF1,AZGP1,INO80C,HBE1,ABCB1,PSME2,AZIN1,NKX3-2,TBC1D10C,MAGOH,CCL19,GTF2E2,MLF1,LBH,JAK1,FBXO42,TMEM215,ZNF24,SERPINB10,TSEN54,MEST,FZD4,MTPN,WDR77,ATP6V1G1,LYG2,MFSD6L,ZCCHC10,SYN3,MX2,GPBP1L1,AAMP,MYH2,SNAP91,HEBP1,SLC7A9,ALKBH4,PACSIN3,PGK1,ROPN1B,VRK1,TMIGD1,DNAJC5,DYNC1I2,S100A6,CYP27A1,CDC73,ZYX,UBAP1,LHX2,MMP9,BTF3,P4HA2,JOSD1,SUPT7L,KIT,RS1,LSM3,AFTPH,OR4D9,RARRES2,GRSF1,PIWIL4,CSNK2A1,KPNA1,GSTO2,KBTBD2,GNG7,CTNNBIP1,ATF4,ZNF593,ARMCX5,PRPF4,IMPACT,AGER,CD58,IDH2,FKBP14,RAB18,CCT5,ENPP4,PSMB5,MCOLN1,SBK2,SORD,SLC39A7,FBXO32,ANAPC2,AGK,SMCP,HCRT,CAMK2N1,FGFR1,PYGM,OR4K1,SHC1,RCVRN,FAM89B,PEX3,CCDC127,CD200R1,CRYGB,PPP3CA,KCNJ11,PRMT2,TACR3,CIB3,BUD31,TMX4,SRP54,CAMK2G,CCDC47,SCFD1,TTC4,GHITM,TUBG1,RPL15,CACNB4,FAM199X,CLDN11,NIPA2,PAEP,RABL2B,TRAPPC1,SPTAN1,SLC35E3,RNASET2,LRP12,NPY2R,PKNOX1,ADRB1,ZDHHC14,RFX4,FRMD8,HEY2,RBM17,PCDHB8,SIX5,TRIM21,ACTA2,ARMCX2,SPR,GALNT12,ARFIP1,PPARG,NFIL3,HECW1,TRIM37,ZBTB38,PTPN1,HNRNPC,SETD5,RMND5B,SLC25A21,RBBP7,PGS1,FIBIN,SNX20,L1CAM,TLR9,COMTD1,FNDC8,FGD2,APEH,AKT1,DLX1,DPP10,PRRC2A,CRABP2,DKK3,IL20RB,SF3B4,ASMT,CCNI,RAB11A,PPIL4,CDO1,LYAR,TOM1L2,GNRHR2,UST,PFDN5,EXOC8,RND3,CNP,NUDT3,B9D1,TMEM156,GSTO1,SOCS5,AK2,GALNT1,CCDC69,PSMA3,MRPL13,MDM2,MGP,EHBP1,E2F6,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,MRPL23,GDI2,GFM2,KLHDC8B,RNF141,DOK4,ARHGAP1,KLK9,PLA2G5,PDIA6,UBR7,SDR42E1,PRIM2,SNRNP27,CD99L2,TRIM32,SLC17A5,SLC25A31,ZNF671,UGCG,MEAF6,LYPLA1,LIG3,RPS14,TMEM219,ATP6V0B,EDF1,ZNF207,POLR3H,TMUB1,C1QC,TRIM3,ZMYND19,SLAMF9,TAAR1,CCR6,SEC14L1,ZNF319,ID4,ZNF397,APOBEC3A,XAGE5,GLUL,CNIH4,NCKAP1,NRP1,CDK5R1,CLU,ATPAF2,KIAA0232,LMO4,LTBR,GAL3ST1,OR4D11,CASK,FGFR1OP2,GABARAP,PRPSAP1,ELMO1,GRPEL1,TCP11L2,UBE2D3,ATP6V0E1,CCT2,CHRM4,UBE2A,ARMCX1,STRBP,P2RY1,ING1,IRF1,OR8B8,TRIM23,NAIF1,NHP2,SLC38A9,OSM,IL15RA,RMND1,PPP1R2,FAM78A,MIOS,ENY2,RAG1,MEF2A,IMMP2L,SLC35A1,DHRS4,MRPL50,MRPL24,ZNF304,SNAPIN,KLK3,SLC30A5,MYL12A,CYP39A1,HSD11B1,SWAP70,LRRC69,FAM8A1,NCR3,EIF4H,ITK,CHDH,GNRH2,SENP5,GALNT4,IDH3B,CTNNBL1,GRM2,CYP11B1,PYDC2,TLR3,JAKMIP1,ADGB,GPAA1,OR4S2,TLR10,WDR82,CD28,ZBTB25,FXYD6,NAB2,SYNGR2,CYTH2,RNF11,APOC4,TAF7,CRYAB,PPY,ROMO1,GNL1,SELL,KIAA1143,ZNF473,ATP1B3,GNB1L,DNAJC2,LAMP3,REEP6,CHPF,MATR3,CNOT6,S1PR4,FAM169A,TNFAIP1,TMEM11,KCNAB1,CRADD,PPP1R3C,AGTRAP,SEMA5A,APBB3,MCMBP,KLHL3,CFL1,IRGQ,BRIX1,RNASE6,DPM2,TP53I3,RNF40,RPS26,DDX1,DAP,KDELR2,ZC3H11A,CCL27,METAP1,TMX2,HTR1A,WSCD1,ELF1,SFRP1,FGF23,GOSR2,SLCO1B3,CYP2R1,CD14,PRR5L,SLC25A39,RANBP6,G6PC3,ZNF704,EXD2,PTPMT1,KBTBD6,FARSA,UBE2H,PNMA5,MANBAL,CD86,SLC2A8,PSENEN,OXCT1,ENO2,TAS2R39,MYC,LILRB4,TMEM50A,SMG8,CD40LG,FEM1A,EEF1E1,CMTM6,VPS26A,MKLN1,CCL28,MAB21L1,RAB35,KCTD10,SHISA2,PPP1R8,OR5V1,GPR173,PSMG3,TOP2B,GEMIN8,MYL6,RPS9,TIRAP,SEC23A,TUSC2,SLC6A3,CASC3,CNKSR3,TCF21,CALML5,PNMA1,VAPB,SP2,HEBP2,PSMA6,PCSK9,KBTBD3,CLEC1A,AKAP1,DNAJC24,PARM1,CPSF4,LCN8,CD63,AGA,CACNB3,AGR2,PCBD1,TTC23,NLGN1,MORF4L1,TMEM174,TNFAIP8L3,SLC48A1,CDC42,SLC38A1,DUSP10,BACE1,CLN8,ACO2,VPS16,SYK,SLC25A26,FTH1,SNX1,PSEN2,SLC35F1,ALB,CCM2,PIWIL3,IL2RG,PAAF1,TFPI,PRKCA,BET1L,KLHL26,MMD,WRAP53,GAS2,EEF1A1,TRAPPC4,UCHL3,RPL39,OR2AT4,TTC33,C2CD4C,FAR2,BRD3,SURF6,TMEM108,DVL2,TESK1,IZUMO4,ALDH1A3,AHCYL1,ADM2,HNRNPH2,HMOX2,NPTX1,CLIC4,MAGED4B,COX11,ADIPOR2,LAP3,C2CD2,EFHD1,EXTL2,RCCD1,ALPL,SLC20A1,PYGB,TRIM6,PDE8A,PSMB9,HOMER1,FOXP1,SLC4A10,SAMM50,KCNJ8,ENC1,SRXN1,FKBP1A,DNAJC30,P2RY12,ST3GAL4,MRPS18B,EHD3,NT5C2,DOLK,ZMAT2,CRYM,SAMHD1,PHACTR1,TPH2,KCNS1,SPRYD4,API5,RPL9,RNF5,DGCR8,TST,SKA1,CSNK1E,GRB10,PAK6,ELOVL4,CHMP2B,RBP5,EIF3D,DNAJC4,ERVFRD-1,POLD4,MAN1A2,AKT3,CCDC92,CUL3,COX16,OR5A2,CPLX1,ARMCX3,PLSCR3,UBTD1,TMPO,MAD2L2,POLR3GL,COX6A2,RBBP4,ATF1,FAS,ABCB9,CARHSP1,KLHL9,NPC1L1,TIMM8A,C2CD2L,DNAJB4,TXNRD2,AKAP17A,RAD21,RAP1B,POLR2G,COQ10B,AIFM1,SNX14,FITM1,LAT2,ACTR1A,ACVR1B,CAMSAP2,FAH,RPL10A,CTDSP2,SDC2,LRRC4B,GREM1,TOMM40,MPHOSPH6,FABP4,COX4I1,ANAPC4,ARPP19,GDPD3,HDAC3,MRPL53,RPL29,GLRA2,MAP1S,BHLHE40,PI16,KRT222,CNTFR,PDP2,NEURL2,SMNDC1,POLR2D,SNX12,DRG1,FGF3,SRPRB,ERLEC1,CEP85,NDP,SNX33,TMEM42,USP13,MED23,SDCBP,ZHX3,ATP6V1E2,IL7,SH3BGRL,ATXN1L,EXOSC3,SRSF4,NECAP2,PID1,MYL12B,GINS3,ENHO,GPR146,OPTN,KCTD11,APPBP2,CLEC7A,ARPC2,ORMDL3,FOXJ3,RAD23B,UFM1,USP30,CHN2,TMEM60,HBEGF,AIF1,CALU,HAX1,EGR2,LRRC20,RPS3,OR1F1,YIF1A,OR10Q1,CA8,RAB3A,SMYD3,DDIT4,FAM91A1,LCN12,KPNA2,CTNND1,NMBR,LGALS3,MAP4,LUC7L3,HHIP,ZNF652,ZNF177,PPME1,HSD17B11,C1QTNF1,AUH,TFRC,TTC8,IDE,ZNF267,IPCEF1,MND1,GGPS1,TSPAN11,HMGA1,OR1S1,SH2D5,UTP6,FOXI3,TMBIM6,CCT8,PABPC1L,LSM2,SOD3,DUSP22,GFOD2,ADAMTS20,FAM187B,MRPL49,GABRB3,YWHAH,MTMR2,PLCL1,ICAM1,DNAJC7,CD83,RPL12,UQCRQ,KCTD12,SPINT2,ZNF688,RGMB,BCL2A1,TMEM45B,APTX,AP2A1,HRH2,MIF,RBM15B,EEF1B2,ZNF189,TFDP2,C1D,ZNF22,ACTR3B,NTNG2,LRRC8D,ETFB,VIP,WNT10B,DGCR6L,FBXO11,RBBP9,SPSB1,TSEN34,FTSJ3,GSTM3,SYNDIG1,TOX,PTRHD1,KPNA6,RWDD4,IRF8,CYB561,BET1,FCER1G,SLC25A46,TBC1D17,TMED4,HEXIM2,HSD17B1,PRDX6,TAX1BP1,AP2M1,KIN,TP53,CRELD1,NFKBIL1,INMT,TRIM35,TRAFD1,PKIA,PPM1B,MGST2,SENP8,STX7,GADD45B,HBA1,LIMS2,GPC4,NECAP1,MZT2B,OSGIN2,OR10A7,ZNF250,SERTAD3,MT3,EIF1B,GABARAPL2,PML,DNASE1L1,PSMA4,ZNF790,TAX1BP3,RDH12,CALY,TNFSF12,GABPB1,SCGB1C1,ARF4,TXN,MAF1,RPS12,CYB5D2,ZBED3,DAG1,MTHFS,DUSP6,PPIF,SETD7,PHF21A,SLC1A2,THNSL1,COX5A,CAMP,TRMT61A,RHBDL3,GPD2,OMG,CELA3B,LBR,FBXL7,CYP11B2,STYK1,POP7,RNF181,RPRD1B,DCAF4L2,TSPO,SNRPN,LYPLA2,RASL11A,CLSTN3,TBC1D19,CSTA,RGS6,ALOX5AP,ELOVL6,TFPT,MECP2,ZNHIT1,NUP35,SLC25A14,PRDX4,ORAI2,CHST7,SERPIND1,CRYL1,RPL24,OLFM2,ENO1,GNPTG,ACADS,PTGES,RNF128,PPP2R5A,VASH1,GAPT,TLR7,RALA,WDR55,FTHL17,F11R,G6PD,ADK,SERPINB6,EXOC5,SYBU,NAA15,CHORDC1,ZBTB16,ANAPC16,OR5B3,BRMS1L,FBXO34,HCST,DHRS1,PAPOLA,RHAG,IL12A,TLR1,OGDHL,CAPG,SAR1B,CCR5,PGRMC1,METTL15,BABAM1,NEUROD2,TMEM147,USP8,LGALS8,COX8A,GPR171,DHX38,PTK7,SNAP29,JAGN1,NDUFAB1,HTRA2,RPL27A,CBLN2,NUDT12,TYW5,IL1A,BCL7C,THBD,OR4D6,PPFIA2,CNDP2,CINP,FBXW11,FBXO44,ARPC3,DKC1,LRRC3,HR,DNTTIP1,AGPAT5,PLD3,PCYOX1L,CREG2,PIK3R2,UBE2K,PDE1B,PCNA,DDX23,SPRED2,CDAN1,OPRM1,CTSC,TMEM126B,NDUFS6,NXT2,RHOBTB1,FZD3,CD247,IKZF5,CHST2,HNRNPA0,RNF144B,ARG2,DNAJB9,GNAZ,RTN4,GLRX5,GAMT,ISX,SIAE,CNRIP1,FKRP,LPAR2,OR10A4,ELMOD2,USP15,GNG12,PABPC1,NTRK2,APOBEC3G,ZFAND2A,METAP2,MME,SEC22C,CTXN1,MAPRE1,NRN1,MUL1,SMG9,GNG10,MOXD1,RPA3,CCDC160,SIT1,FDFT1,NEGR1,RORB,CKS2,ABHD5,CXCL13,EPHX1,RWDD3,TXNDC12,SDHB,GFPT1,ATG4C,SNRNP48,FRRS1,CENPW,UCN,CRLF3,INO80E,DEPDC1B,PTEN,RLIM,UAP1,THAP7,PTAR1,MGAT5B,CLDN3,ADAM21,CLDN24,OLFM3,SCG3,COMMD3,BMPR2,PPP1R1B,RND2,SCGB1D1,SHISAL2B,NLRP3,ILDR1,CCS,RASD1,CFC1,IER2,CHPF2,NDUFAF3,HERC4,DKK1,NR2F6,CNTN2,ASNSD1,ZMYM3,CRIP1,PSMB1,ZNF365,BAG3,ILF2,ORC5,OXSR1,KRAS,RPS16,RBM22,RRM1,TOM1L1,KDELR1,PGGT1B,SLC38A7,OXTR,KCNC1,LAPTM4A,FBXL19,MRGPRX3,MTA2,CCDC86,SUFU,CHCHD4,CHIC2,SLC16A1,OR13C8,HINT2,NUF2,TMEM101,TPD52,DBT,RAPGEF5,ELOVL7,DAPK3,DSTN,RPS27A,PCDHB13,CHAC2,G3BP1,PSORS1C2,POP5,METTL21A,MRPL18,FGFBP1,MFSD5,CCDC134,TCF19,SLC30A7,SLC6A6,TSPAN18,GANAB,RPS6KA4,BBS5,XCL1,OCRL,MAT2B,ZNF664,MLC1,PDHB,DDX46,OVOL1,DHX15,RHEB,FBXL14,RELL2,TRIM15,GPX1,RAB27A,GRAP2,RPS7,PSMD4,NPPC,LRRTM3,DAAM1,MRPL11,SCLT1,PPP2R5E,SH2D1A,SLC11A2,UBB,LMAN1,NPSR1,HSPA13,LSM10,ANKRD34B,LARP4B,PMP22,SERPINA1,STX11,OR2Y1,REEP3,ST6GAL1,CSGALNACT2,RPL7L1,CSTF3,HENMT1,TMEM179B,TOMM22,BFAR,UBA3,CBLL1,TOR3A,GLRX,PRR3,IL22,STAT2,SAV1,TAGLN3,EPCAM,PCDH17,SRSF7,FASTKD5,CST11,SNX22,SFXN2,TMEM117,TMEM170B,MRPL34,NDUFB6,GNAO1,CYP21A2,NCDN,UBL3,IMP3,IRAK4,GNPDA1,COMMD6,KCNJ3,B3GALT1,TMEM30A,AFAP1L2,EP300,ADAMTS10,PEA15,RNF8,AKAP8L,APOBEC3F,MAP2K1,PLCB2,HSD17B6,TMEM167B,COPS5,STAT5A,PRDM4,FEZ1,EIF4A2,OTX2,MAGEH1,LRRC3B,FPGT,SOSTDC1,MORC2,SSR2,ELOVL1,SNRPB,TPM3,EFNA3,PTPN4,GPX7,CHRNB2,OR10P1,RIT1,FAM43A,NLRP9,RNASE1,CGB8,TMEM45A,TMEM237,LAMP2,IFI6,AR,OR8B12,PPM1K,CCL2,GSTP1,LLPH,USP3,CAPN1,ASZ1,METTL22,CYP2C8,TNFRSF1B,CDNF,CEBPG,TGFBR2,ANP32A,SPIN3,CLLU1,RPL23,STOM,CTTN,VAMP7,HP,SEMA4C,SLC2A3,FBXO7,RABGGTB,RCL1,SF3B5,IL2RA,PPAN,AQP2,SMAD1,CLEC18A,CHST13,ZNRF1,PPP2CB,FKBP8,KLHL24,GABPA,PRSS12,PPP3R2,TIMP3,MPDU1,VAMP8,TMEM70,TTL,PMM2,PRMT6,BIRC2,MTM1,FCGR2B,IFIH1,NUDT7,CER1,POLR1B,SIAH2,CHCHD6,HOXC4,UPK1A,EPS8,RFXAP,SS18,MRPL22,CDCA7L,UMPS,RAB19,CD1C,UBP1,MAVS,KLHL22,CHMP4C,CEP19,SOX14,PDAP1,SLCO2B1,CX3CR1,IGF1R,FAM177A1,DCTD,SCNM1,MCM4,DROSHA,NR2E1,FLOT1,ORC6,THOC2,STARD4,SEPHS2,CLEC2B,CBR3,JKAMP,ADD1,KLF1,CLPB,FEN1,VDAC1,ODAM,APOBEC3H,LANCL2,GLRX2,ASB7,PRKACB,ZNF326,MYBL2,PLEKHO1,ERAS,GSTM5,OTOS,CNOT2,CRHBP,PKP4,GPR176,CLDN12,ELF5,CCNY,CHKB,FCGR1A,VGLL4,DNAJC19,SCML2,TRIM68,ETF1,LRRC8B,TAF10,PRDX1,FAM53B,PREB,NPW,NFKBIA,TUSC1,ATG7,RNF34,ACBD6,DENND2D,COPS7B,KLF4,OR4D2,OR10A6,SERPINC1,HLF,ACP5,EGFL7,TMEM59L,ATP6V1A,SLC7A8,RFC3,FBXO22,REG1B,GPM6B,UBE2W,DHRS13,PARL,GTDC1,LRRC61,UBIAD1,POLR2B,TSNAX,GNPDA2,TMOD2,TM4SF19,CRAT,NAPA,NOTCH2,SOBP,PTPN11,DECR2,AVL9,IQCK,TP53INP1,VEGFA,FAF1,REN,CCR1,SMPD2,TBC1D13,NCBP2,ATXN10,SOD1,ASTN1,DTWD1,DRGX,HDHD3,SHOC2,DDRGK1,RPL32,PSMA1,AK3,CLCN6,HMGCS1,SLC25A12,HARBI1,TMED5,USP16,PFDN2,LTB,TCEAL1,SLC35F2,TRMT112,SYNCRIP,DIO1,SLC16A10,VGLL2,CLDN9,PRICKLE2,RNF148,MSTN,PPP1R1A,RPL27,PTH2,MTF1,FAM83C,UGT1A1,ABCG2,LTA,MRPS9,SPSB3,TOR1B,KANSL3,MNS1,POLB,POLA2,UBASH3B,CCNH,SEMG2,KIAA0513,IFNB1,BTN2A2,UBL5,CSH1,TEX264,SNRK,SRSF2,UBLCP1,GSTA1,SERPINB1,TRAK2,ST7,AVPR1B,KLF9,STUB1,PIP4K2C,ACVR1C,NKIRAS2,FAM181B,RBM38,IL1R2,TMEM41A,SLC22A17,TNKS,CYP1A1,ST8SIA5,PLS3,BST2,PPP2R2C,SPON1,STK4,HINT3,VRTN,SLC25A10,RPRD1A,GTF2H5,DDX50 |
| 1.164e-10 | -22.87 | RAB2A (RAB2A, member RAS oncogene family) | protein interactions | 5862 | 553 | 224 | 19454 | 5460 |
RPA2,SCLT1,LEMD3,CSNK1G3,SPTBN1,SNRNP27,CDC42,TOMM20,PIP4P1,RGS2,MAPKAPK3,ARFIP1,IGF2BP1,TBC1D25,ATP1A1,CFL2,ARHGAP21,SLC6A6,GORASP2,OTOS,GMDS,SUCLG2,ROCK1,GARIN6,SRC,NECTIN2,MOB4,TFRC,CCM2,TMEM165,SNAP29,UBIAD1,AKAP12,RAB3B,SLC6A8,SLC16A1,BCAP29,TMEM70,TRAPPC2L,ADIPOR2,GAPDH,CAND1,MIF,LMAN1,SELENOI,SLC38A2,CD99L2,COQ8A,ITGA6,COMT,ADD1,SLC39A10,RAC2,CTBP1,YIPF5,EMC1,GOSR1,HNRNPA0,RER1,PHB2,ABCC5,RAB5A,EP300,AKAP1,LAMTOR1,SLC38A1,ICA1,OST4,SLC30A5,SLC1A3,VDAC2,FAM83B,RAB4A,RANBP1,ARFGEF1,SNAPIN,VDAC1,SLC20A2,ROCK2,SLC35A2,RAB8B,TMEM87A,EFNB1,AGR2,STAMBPL1,LAMP2,RAB5C,SLC38A9,PPFIBP1,RAB1B,ASIC1,RHOH,VAMP7,HSP90AB1,CHMP2A,RAB35,STX5,TIMM23,COX6C,STOM,GOLGA5,SLC12A2,UBA52,PIP5K1A,SEC22B,ADIPOR1,ARHGAP1,CNP,YKT6,SLC7A1,PIK3R2,DAD1,RPA3,RHOU,FLCN,ITGA2,RTN4,SQSTM1,EPHA2,CDC73,NRP1,DEPDC1B,HMOX2,F11R,RAB14,YES1,SNX3,RHOJ,FERMT2,VIRMA,GNAI2,CEP97,VAMP3,SCAMP2,WDR45,KRIT1,TRAPPC13,CCDC47,MAP1LC3B,EEF1A1,SLC29A1,CTNND1,SFT2D2,SLC25A10,RAB1A,DLG1,SEPTIN7,SNAP23,SLC2A1,TIAM1,RELL1,TMEM199,LAMTOR2,LAMP3,RAB23,ALCAM,ARF6,POLE3,CAV1,TES,CDCA3,MYL6,NOTCH2,RND2,RAB6A,RP2,STX7,UPF3B,RABAC1,TMEM185A,PMAIP1,BET1L,WDR20,RHOB,SLC7A11,VEZT,PKP4,RAB11A,TOMM40,MB21D2,LAMTOR3,ACTB,CHCHD3,FAM91A1,ARF1,CYB5R3,SEC61B,EZH2,VAMP2,RPN1,CTSA,GDI2,RAB6B,STX12,ITGB5,CYB5B,MARCKSL1,RAF1,TPD52,FAF2,YIPF3,TULP3,ERLIN2,ARL5B,ETFA,FLOT1,RNF26,TRIP4,AKT2,SLC39A7,PLCB1,RHOG,HAX1,LRRC57,PIK3R1,PRKCQ,CNTROB,TMEM237,CBFB,WDR6,PHB1,GJA1,ATP6V1A,SGMS1 |
| 1.175e-10 | -22.86 | ORF7a (ORF7a protein) | protein interactions | 43740573 | 471 | 196 | 19454 | 5460 |
CYB5R3,SEC61B,AP2M1,REEP4,RANBP6,ABHD12,TM9SF4,ELMOD2,LMNB1,ELMO2,HSP90AA1,SCFD1,TMEM168,RABAC1,ATAD1,NPTN,ZDHHC17,TOR1AIP2,NOTCH2,PGRMC1,RAB6A,VAPB,ARCN1,NDUFA5,SLC25A3,WDR6,CYB5A,XPO5,GJA1,SNX2,SPTAN1,NUP35,RAB11B,PPIA,STOML2,UBXN6,CDK5RAP3,BCL2L1,NDUFA4,SCD5,JAK1,ATP5F1D,SACM1L,TMED7,RPS27A,MACO1,MARCKSL1,IFNGR1,ERLIN2,YIPF3,FAF2,RPN1,STIM1,PLD3,ENO1,STUB1,ACAT1,SLC25A4,RAB14,SEC63,TECR,HMOX2,ARFGAP3,XPOT,NAPA,AP2A1,RDH10,PPIH,TCEA1,MTDH,SPCS2,YKT6,TMEM209,NHP2,ARHGAP1,SEC22B,UBA52,RABL3,GOLGA5,LMNA,SRPRA,HACD3,PTPN1,SEC23A,COG1,TOMM70,CALR,HM13,ESYT1,POR,OSBPL8,DNAJC7,PC,TOM1,HSPE1,HUWE1,ARF4,NDUFA2,CCDC47,RNF121,VDAC2,BST2,LRP12,LDHB,TMEM38B,SLC30A5,PSMD1,CKB,ZMPSTE24,SLC38A1,CMC1,SNRPA,DDX39B,TAPBP,SSR3,FXR2,UFL1,BET1,PAFAH1B1,MRPL12,SEC22A,CTBP1,CD63,RAB35,STX5,RAB1B,EIF2S1,HSP90AB1,VAMP7,WWP2,RAB5C,FAM20B,DDRGK1,XPO1,PGAP4,RAB18,PRPS1,TFG,ARFGEF1,DNAJC25,TMEM59,PTRH2,PLS3,HGS,CRKL,NDUFA12,STX10,INTS12,EIF2S2,SEC61A1,SLC25A1,RAB2A,GORASP2,NCAPG2,SORD,ATP1A1,OAT,BANF1,RPL27,TEX264,LCP1,ZC3H15,GRPEL1,SPTBN1,CDC42,SSR1,SDCBP,LEMD3,CAMLG,ACSL4,STT3A,GNPAT,TRAPPC3,DSTN,RPS27L,ARL6IP5,DNAJC1,RPS16,TMPO,ILVBL,LMAN1,DHRS7,KARS1,RPL10A,ATP2B4,SLC25A11,YIF1A,SRPRB,AKAP12,FKBP8,TP53,PREB,STRBP,SURF4,TFRC,TSPAN3 |
| 1.183e-10 | -22.86 | regulation of tumor necrosis factor superfamily cytokine production | biological process | GO:1903555 | 195 | 100 | 18204 | 5365 |
ADIPOQ,VSIR,IGF1,CD2,IL10,MIR144,MIR101-1,IL1A,CX3CL1,GSTP1,MIR920,CX3CR1,TNFAIP3,FCGR2A,SELENOK,LY96,TMEM106A,PTPN22,SYK,CLU,HMGB1,DHX9,FCGR2B,NFKBIL1,MIR98,SELENOS,AGER,MIR361,PYCARD,JAK2,TIRAP,MIR708,SPHK2,ACP5,MIR105-1,ARG2,OAS1,DEFB114,MIR488,GHRL,TLR2,CD14,MIR206,DICER1,MIR130A,CCL19,CCR2,MIR657,IL17F,CD47,FOXP1,IL12B,IFNG,MIR185,TLR3,AKAP12,IL6,CLEC7A,FRMD8,HSPB1,CD86,MIF,CCL3,SASH3,LILRB1,ANGPT1,BCL10,MIR132,DDT,FOXP3,CD274,PTPN11,TLR4,TRIM27,LEP,MIR140,IFNGR1,TYROBP,RIGI,TICAM1,TLR1,RAD21,MIR204,MAVS,CD36,IL23A,MIR195,CHRNA7,SETD4,TLR9,IFIH1,PIK3R1,TSPO,IL4,GPNMB,MYD88,MIR149,LILRA2,PSEN1,LILRB4 |
| 1.197e-10 | -22.85 | DPP4 (dipeptidyl peptidase 4) | protein interactions | 1803 | 445 | 187 | 19454 | 5460 |
PHB1,MRTO4,KRT8,XPO5,SPTAN1,PPIA,PIK3R1,PDIA3,HNRNPA1,NCR3LG1,CDK5RAP3,LRRC57,TMEM30A,PPAN,HNRNPA2B1,PLCB1,SRSF7,ERP29,BAG2,TPBG,RAF1,ERLIN2,IFNGR1,ACTN4,RPN1,VAMP2,PLD3,STX12,ACTB,CHP1,CUL2,VEZT,MYO6,LMNB1,CXCR4,DNAJC3,HADHA,DUSP26,STX7,PGRMC1,RAB6A,ATP5PO,MYL6,NDUFA5,SRPRA,PTPN1,CHID1,ARF6,RPL35A,CXCL11,MDM2,ATP5PD,LAMTOR2,CALR,ESYT1,SLC2A1,OSBPL8,STX8,IGF1R,SNAP23,TMX3,PTGES3,PRDX4,MRPL11,GFOD2,CCDC47,ACTR2,GXYLT1,GANAB,YES1,SNX3,TMOD3,TECR,CTSD,SDF2L1,XPOT,RPA3,H2BC12,PIK3R2,CERS2,NF2,SEC22B,ARHGAP1,CNP,HSP90B1,RPL26L1,HNRNPH3,MET,PTK7,SPINT2,CORO1C,HNRNPL,COCH,GFOD1,LANCL1,DKK1,PPIB,CCL11,IKBKB,MAGOH,PDIA6,EFNB1,MYO1B,VDAC1,RAB18,CXCL10,HNRNPDL,RPL28,FKBP2,PCDH19,TMEM59,RPS23,VDAC2,FAM83B,ATP6AP2,HNRNPC,SERPINH1,TMEM106B,PHB2,TRA2B,HNRNPA0,EMC1,SAP18,TOMM22,GPC4,CSNK1A1,CD4,CXCL9,CAND1,SURF6,LMAN1,DHRS7,CXCL12,DPP4,KARS1,TPM3,GAPDH,CCL5,BCL10,AGPAT1,AKAP8L,ATP2B4,ATP5PF,SLC25A11,PALM2AKAP2,ERO1A,ABCE1,CSE1L,H3C1,TP53,PREB,ARPC3,RBM34,TMEM165,TFRC,SURF4,GNAI3,SLC25A24,NECTIN2,CDIPT,MACROH2A1,SEC61A1,SRC,ROCK1,SLC25A1,CHPF,GORASP2,CNNM4,CFL1,CFL2,DNAJC10,ATP1B3,CALU,ATP1A1,BANF1,NBN,DLAT,FTSJ1,AIF1L,HSPA5,CLU,MARS1,GRPEL1,SPTBN1,NTPCR,SSR1,CHPF2 |
| 1.214e-10 | -22.83 | Disease | REACTOME pathways | R-HSA-1643685 | 858 | 354 | 10285 | 3229 |
MAP2K3,FGFR1OP2,MMADHC,ELMO1,CBLL1,POLR2L,RBPJ,POLR2D,STAT5A,POLR2F,PSMD14,RNF5,PTPN11,SOD2,CXCR4,PSMC4,PSMB1,PSMB6,PSMA2,PSMA4,FGFR1,NUP153,CHMP4C,HGS,ALB,AGK,MAP3K11,BAD,RPS4X,SLC25A5,CALR,RPL3,NUP37,VPS28,RAN,EIF2AK2,TLR3,XRCC5,GTF2F1,ADAMTS20,PPP1R3C,TLR1,RPS7,CD36,TLR10,FGF22,RPL7,LMNA,TCEA1,KRAS,GTF2F2,TENT4A,PIK3R2,HSP90AB1,PRDX1,RPL10,APH1A,RPS3,SLC25A4,IRAK4,MET,NFKB1,RPL22,CD9,SEMA5A,RPL13A,AP1S2,PSMA1,CCR5,SMAD4,SFTPA1,FURIN,MAP2K6,PSMD1,HDAC6,HSP90AA1,PIK3CA,AKT1,RPL28,VAMP2,SV2B,POLR2C,RPS10,FGF17,ZMYM2,CD80,RPS27L,NCSTN,TRIM24,ADAMTS10,FZD4,PSEN2,GTF2H2,TLR4,DERL2,ELOC,CDKN1B,GPC1,CREB1,APOBEC3G,PIK3R1,CTNND1,RPL19,CSK,BRAP,PRDX2,CD28,GTF2A1,BANF1,B2M,JUN,HDAC11,MYD88,PSME2,GTF2E1,CHMP2A,SPON1,FAU,RPL32,MYC,NFKBIB,HDAC5,CD4,PIK3R3,POLR2I,AP2M1,STAT1,NUP107,CSNK1A1,TICAM1,AP2S1,RPL24,PPIA,NFKBIA,TAF2,OGN,RPL10A,PC,SFTPD,KCNJ11,RPL29,SRC,TAF10,TAF7,SUPT4H1,POLR2G,ACACA,SMAD3,RPL27,GPC4,YWHAB,MMAA,STX1A,ERLEC1,TLR6,SNAP25,ICOS,AP2A1,CD247,PEBP1,PSMB3,FASLG,PSMA5,LRP6,NCBP2,RPS27A,RPS13,RPS29,CD86,VWF,FZD6,CAPN1,RPS16,ERCC3,PSENEN,RPS20,FGF16,RPL6,DERL1,CDK8,KIT,VTA1,GTF2H4,MMUT,GTF2E2,PRELP,PSME1,RPS15,CDK7,RPS9,CTBP1,FKBP1A,PPP2R1A,RANBP1,UBB,RPS11,RPS2,RPL31,JAK2,NOTCH2,RPL12,NUP50,MMACHC,RPL26L1,TLR5,DAG1,LY96,PSMB11,PSMB9,SUPT5H,FBXW7,FGF3,RPL27A,GSK3A,GYS1,CFTR,PSMD12,CDK5R1,GRSF1,RPSA,RPL7A,XPO1,FEN1,AKT2,MNAT1,RPL39,RPL26,POLR2B,PSMD10,PCCB,RPL37A,RAF1,MAP2K1,ISG15,FGF1,CHMP5,TXNRD1,RPS28,HDAC3,NUP62,RPL15,VPS4B,RPS5,SHC1,IKBKB,TLR2,PAK2,SFTPC,IDH1,GTF2H5,PSMD4,PHB1,CTNNB1,RPLP1,TAF9,GTF2B,PSMC1,CREBBP,RPS24,CDK9,PSMB2,NUP42,RPL23A,PPP2CB,HRAS,HMGA1,TSG101,SDC2,LUM,AVPR1B,PSMD7,SDC4,SKP1,RPL23,CBL,SYVN1,AP1M1,TTR,AGTRAP,PSMB5,PSMA3,PSMB7,DNAJC3,PSMD3,OS9,CDK5,CPSF4,TNKS,SMAD2,PSMB10,PSMC5,RPS17,RPS26,TNKS2,CHMP2B,RPL8,HBEGF,RPLP2,PSMD6,NUP35,RPLP0,FGF7,TIRAP,ERLIN1,KPNA2,CDKN1A,RPS14,CAPN2,RAP1A,SYT2,FGF10,PIK3AP1,FMOD,EP300,KPNA1,AGGF1,UBA52,TGFBR2,ATG7,RPS23,RAP1B,RPL4,GTF2A2,RPS12,MDM2,RPL9,RPL18,PPP2R5A,ARF1,DKK1,PPP2R5E,RPL35,RPL17,CCNH,FGF23,SEM1,CD14,ADAMTS1,PSMB4,RPL10L,ERLIN2,LMNB1,PSMC3,EEF2,TAF11,VAMP1,SSRP1,CLCN6,AKT3,PSMA6,HEY2,GAB1,RPL35A,VPS4A |
| 1.290e-10 | -22.77 | LIN28B (lin-28 homolog B) | protein interactions | 389421 | 214 | 104 | 19454 | 5460 |
GLE1,RAF1,OTUD6B,H1-3,H1-6,MIR9-2,MRPS11,MIR206,MIR31,MIR1-1,MRPS26,MIR221,MRPS35,MIR143,RPL6,DDRGK1,MIR9-1,RPS10,SRSF1,MIR7-2,RPL8,MRPL57,NOP53,STAU1,HSCB,MRPS7,MIR106A,NGRN,SNRPA,CCDC86,SF3B1,NOA1,FTSJ3,ZCRB1,FYTTD1,H1-1,NSA2,RPS5,HNRNPC,MYC,MIR98,SNRPB2,MIRLET7D,SURF2,RPS9,MIRLET7B,RBM34,SRP72,STRBP,MIR15A,NOC4L,MRPS33,CDC40,SNRPG,SRSF12,MIRLET7C,MEPCE,MRPS18C,MIR200A,ZC3H11A,RPL3,SNRNP70,MIR34A,NOL12,CMSS1,GRSF1,MOV10,COPS5,MIRLET7G,RPS16,SURF6,ZBTB2,NOP9,MALSU1,NCBP2,MIR429,DKC1,KRR1,MRPS9,MIR106B,MIR25,MIR7-1,ZNF574,RPL26L1,MIR34B,MIR1-2,MIR7-3,RPS15,MIR107,BRIX1,MIR29A,UTP23,NHP2,MIR205,MIR10B,MIRLET7I,RC3H2,MIR145,UBE2H,ELAVL2,ZSCAN25,SRPK2,EIF4A3,PHAX |
| 1.290e-10 | -22.77 | CA9 (carbonic anhydrase 9) | protein interactions | 768 | 214 | 104 | 19454 | 5460 |
KPNA2,CSE1L,SRPRB,TUSC3,RUSF1,EMC2,RAB27A,ARPC3,CCDC47,SLC29A1,ARL6IP5,DNAJC1,CAND1,ALCAM,ARF6,LMAN1,SLC38A2,TMPO,PTPN1,SRPRA,ITGA6,LDLR,C2CD2,HSD17B11,SLC39A10,POR,NPR2,DHRS7,RELL1,CALR,TMEM199,DAG1,ATP1B1,HM13,CERS2,ITM2B,FADS2,GRAMD2B,TMX2,TEX264,SPCS2,ITGA2,SSR1,USE1,ACACA,LEMD3,RABL3,SLC35E1,SCAMP2,CTNNA1,STX10,CA2,NRP1,XPOT,RETSAT,CTSD,HMOX2,ATP5F1A,FLOT1,SACM1L,SLC35A2,RTCB,SEC11A,STIM1,RPN1,TAPT1,MACO1,TMEM59,ATXN10,NUP35,CYB5A,SPINT2,XPO5,CNTFR,SLC20A1,C2CD2L,PTDSS1,CTNNB1,XPO1,EMC1,G3BP2,CSRP1,TIMP3,EVA1A,BET1L,HADHA,MMP14,TOR1AIP2,GINM1,SPCS1,ATP5F1B,LRRC8A,CHP1,TNPO3,ATP6AP2,ABHD12,SLC30A7,SPCS3,VMP1,SLC38A1,DHRS1,RPS5,TMEM38B,VEZT |
| 1.339e-10 | -22.73 | TUBB (tubulin beta class I) | protein interactions | 203068 | 676 | 265 | 19454 | 5460 |
EMC2,FAF1,LTA,OLA1,VRK1,HUWE1,MAP2K3,SLC29A1,MAP1LC3B,EEF1A1,FBP1,TES,EFNA3,AIFM1,DFFA,CDK9,MDM2,KCTD15,DCUN1D1,CDC42SE2,HDAC6,GMPPA,NFKB1,SPP1,SQSTM1,CST11,WNT7A,NCDN,INPPL1,RPA3,CRYZ,PIK3R2,CDK7,CNP,MX1,EDF1,WTAP,HAUS2,ZNF574,RARS1,METTL14,HSP90B1,GRM2,CDK1,UBASH3B,ACAT1,PTEN,MSN,TUBA1B,CCNF,VIRMA,ARMC6,COPE,NDN,LDHA,PPP1CC,ZMYND19,MAPRE1,STK24,TXNIP,UBE3A,OSTM1,PSMD12,TRIM37,CDK20,LGR4,ERLIN2,TXNRD1,B3GNT2,RAF1,STK16,DTWD2,PPID,AQP3,NME1,GDI2,SKA3,EZH2,MAP1LC3A,IFIT2,PHB1,FOLR1,CACYBP,EGLN3,FAM174A,SAV1,CAMSAP2,BCL2L1,RPL23,RB1CC1,DDX23,HADHA,RLIM,NUBP2,NMRAL1,CRY1,WBP2,FBXL4,CDKN1A,DAAM1,NCALD,ALKBH3,LNX2,AP2M1,FAM91A1,MAD2L1,MAT2B,TUBB,DYNLL1,EIF4A2,CUL2,CUL3,ACO2,HTRA2,PFDN6,CBR3,RIT1,PFDN4,PFDN2,HSP90AA1,KLK5,YWHAZ,BRCA1,FYTTD1,MCM8,FAS,MEPCE,TOLLIP,NEDD8,ZMYM4,MGARP,CDK4,TP53,MTCH2,UBL4A,RNF8,BMPR2,DISC1,NFE2L2,TFCP2,CD4,CD274,SSBP1,CDC5L,GRM1,CAND1,GAPDH,COPS5,CD81,MAP4,SMG8,SHC1,H2AC4,TUBG1,RNF113A,PGK1,PML,BAP1,HSPA5,CFTR,CDC42,GABRA1,CSNK1G3,UBE2M,HEXIM1,RNF146,WRAP53,TCP11L1,VPS4B,RPA2,MACROH2A1,PSMC5,B4GALT1,SRC,SMURF1,CDC20,CEP41,PRKCE,KCTD9,SMARCA5,RSPH1,PSMB2,SLC25A1,RPF2,MAT2A,AKT1,UBE2H,ATP1A1,TRIM23,RC3H2,SPOP,SCPEP1,CCT8,RAB8B,RUVBL1,EPHA4,KRAS,MSX2,TNPO2,EEF2,TUBA1A,ANAPC13,NUDCD3,ERRFI1,HGS,PDHA1,PTRH2,TUBB4B,TPPP,MAGED2,S100A8,RAB35,CCT7,HSP90AB1,UQCRH,RAMP3,ELK1,TCP1,SUMO2,DDRGK1,CTNNB1,XPO1,YWHAG,PFDN5,WWP2,IFI16,LAMP2,YWHAB,CBL,POU5F1,AGR2,FKBP4,HDAC5,HSPA8,RCCD1,BMPR1A,DDX39B,PHB2,ADRB2,STAU1,EEF1G,UFL1,TSHR,SYK,PIH1D1,CSNK1A1,PACRG,GTF2F1,ZNHIT6,POLR2B,TRIM29,ATP5F1B,MATR3,SNRPB,BTF3,NXPH3,TBCE,MYC,CREBBP,CRMP1,COP1,ICAM1,PSMD14,CCT2,PELI3 |
| 1.388e-10 | -22.70 | IARS1 (isoleucyl-tRNA synthetase 1) | protein interactions | 3376 | 374 | 162 | 19454 | 5460 |
MIRLET7B,CMTR1,RAN,LMBR1L,APEX1,ESR2,RPL19,MIRLET7D,MAT2B,PSMD6,DYNLL1,MATR3,HMGCS1,MIR98,CUL2,PSMA4,CUL3,MYC,RIT1,COP1,MIR363,ATG3,BRCA1,HDAC5,CRY1,HSPA8,G3BP2,MIR106A,STAU1,UFL1,PAFAH1B1,BET1,PIH1D1,PPT1,MIR141,MIR214,MIR7-2,PHB1,DHX15,SUMO2,MIR9-1,DDRGK1,ATG7,MIR29C,MIR143,WWP2,PFDN5,DRG1,MIR140,RB1CC1,MIR1-1,PEX3,MIR221,AHSA1,MIR31,AGR2,TRAF6,SCPEP1,MIR206,SLC2A8,PABPC1,HNRNPA2B1,CCT8,MIR155,VDAC1,KRAS,LGR4,MSX2,ISG15,GFPT1,JUN,TOP3B,RPL18,MOB3C,SART3,POLR2C,PDHA1,NME1,CHMP4C,PLS3,GLE1,PRSS8,PSPC1,MIR16-1,OPTN,CCNF,VIRMA,AR,USP14,GSTK1,C9orf72,UBE2H,MIR145,RNF113A,MIR34C,MIRLET7I,MIR205,MIR10B,BAP1,RPA3,MIR107,MARS1,MIR29A,RPL4,FBXW7,MIR7-3,CFTR,CDC42,MIR1-2,CAPN1,TPT1,EEF1E1,MIR34B,MIR7-1,ACACA,UBE2M,MIR21,RARS1,RPLP0,GRM2,RPA2,SDCBP,MIR25,SYNCRIP,MIR106B,G6PD,TMPO,CDK9,MDM2,RPS27L,MIRLET7G,SPPL3,RPS16,COPS5,HDAC6,KARS1,CENPP,MAP4,MIR34A,RPL24,H2AC4,SHC1,MIR9-3,RPL23A,ERO1A,MAP1B,METTL18,MIR200A,RAB1A,RIGI,MIR16-2,MIRLET7C,RPL15,MIR200C,MIR15A,AURKAIP1,CCT5,TP53,KBTBD4,COMTD1,MIR20A,MIR17 |
| 1.398e-10 | -22.69 | NAA40 (N-alpha-acetyltransferase 40, NatD catalytic subunit) | protein interactions | 79829 | 976 | 363 | 19454 | 5460 |
MYL6,ADNP,ETF1,UNC45A,NRBF2,COIL,TTC1,NUP50,UPF3B,MYO6,MCM4,RHEB,CUL3,RPL19,RPL35,DYNLL1,AP2M1,RAN,PARP2,CYB5R3,GTF2E2,NUP153,GFPT1,FEN1,ETFA,G3BP1,LASP1,RBBP7,CAMSAP2,RPL23,RSBN1L,AHSA1,WDR11,EIF3D,ATG7,PRPF19,PRDX1,CETN2,CACYBP,RPL7,SNX1,OCRL,RPLP1,HP1BP3,IGBP1,DNM2,THOC2,TMOD1,RPLP0,HSP90B1,TOX4,JUP,EDF1,SAP30BP,NUCKS1,USP8,RPL4,EIF5B,GTF2I,MAVS,MTDH,CSTB,XPOT,NONO,USP14,GMPS,DEPDC1B,ATP5F1A,RPL13A,TXN,LDHA,ZNF622,RPS20,OPTN,PPME1,RPL15,YTHDF2,MSH6,CTNND1,HINT1,PC,ZC3H11A,PSMD7,ESYT1,GLO1,GTF2E1,ISYNA1,G6PD,TOP1,MAPRE2,EHBP1,PIH1D1,KLC2,PAK2,RPL27A,NUP62,STAU1,AKAP1,HSPA8,XRCC5,FLYWCH2,RFC4,PYM1,CHTOP,RBM27,FTSJ3,PAPOLA,USP16,ATP5F1B,PSMD4,GTF2F2,PHF21A,ZHX3,RPL18,MTA2,RANBP1,POLDIP3,RPL28,VDAC1,PDIA6,RTCB,RPAP3,TOP2B,PABPC1,CCT8,YWHAB,FKBP4,TBC1D5,STK4,TCP1,TRIR,AFTPH,EED,FABP5,TNIK,ACACA,SDCBP,RPA2,GTF3C4,SUMO1,MARS1,ZC3H15,PRDX6,RNF113A,ATP1A1,ANAPC4,EIF3G,PTPN11,SUB1,PPP1R10,PSMC5,PSMA6,LIG3,ZBTB33,CRABP2,TFCP2,CHAMP1,MTCH2,SNAP29,CAPZA1,IDH1,ABCE1,RPL3,PALM2AKAP2,RPL10A,RPS2,CDK12,RBM17,KARS1,SURF6,CDC5L,TMPO,DKC1,PLSCR3,RPS16,EEF1B2,ARCN1,SLC25A3,KCTD12,VAPB,CFDP1,HSP90AA1,YWHAZ,SMARCE1,JPT1,NIBAN2,ERH,PRRC2A,ACTB,TUBB,PDLIM3,PRDX2,ZMAT2,RPS9,SART3,JPT2,RPS11,NME1,SKA3,RPL29,NAA15,RBM12,RAF1,ARFGAP1,RAD21,SSRP1,COPS4,RPS27A,DHX16,PCNA,NEK9,ZYX,HSPD1,NUDT5,SCYL2,PDAP1,VCPIP1,HNRNPA1,PDIA3,HMGA1,WDR44,PPIA,ATP6V1A,RPL9,RPL8,PICALM,GOLGA5,SYNRG,UBA52,SF3A1,CHMP2B,YKT6,RTN4,HELLS,DVL2,RPA3,SOD1,HERC4,RPL26,BRAP,PDCD5,FERMT2,SCML2,TMOD3,RPS12,GTF2A1,CTTN,ENO1,FAM169A,PTGES3,TCOF1,NKRF,PPP1R12A,CNN3,ECD,KIAA1143,NME2,CWC15,TES,RPL12,NUFIP2,EIF4B,MRPL12,ZC3H14,PSMB3,LYPLA2,EEF1G,DDX5,GPHN,SF3B1,RPS28,PEBP1,NANP,CKB,CCT2,BAG3,BTF3,PSMA4,LDHB,HNRNPAB,RPL10,STAT1,MATR3,TAGLN2,ZMYM2,VDAC2,CSTPP1,RPS23,TUBB4B,NUDCD3,DHX38,SPC24,RAB18,RUVBL1,HNRNPF,MYO1B,ABCF1,LSM14A,UBFD1,AK2,BTF3L4,DDRGK1,RPL6,DDX50,BAZ1B,CCT7,HSP90AB1,SNRPD3,AASDHPPT,PRCC,SIN3A,PSME2,TFIP11,ARFIP1,PGK1,NBN,PML,DDX46,CDKN2AIP,OAT,IGF2BP1,PDCD4,GLOD4,GORASP2,MTPN,CFL1,ARHGAP21,FAM193B,RPL7A,SUGP1,SMARCA5,NOPCHAP1,EIF4H,MACROH2A1,SRP54,CALML5,CSNK2B,PHAX,PSPC1,CAPZA2,CBX3,DDX42,TP53,RPSA,RPL17,MEPCE,HNRNPK,NUP107,AKAP12,MAP1B,MAP4,TSNAX,RPL24,SMCHD1,GAPDH,TPM3,EDC3,ESD,MIF,CAND1,ADD1,RPL32,METAP1 |
| 1.410e-10 | -22.68 | Influenza Life Cycle | REACTOME pathways | R-HSA-168255 | 146 | 83 | 10285 | 3229 |
RPL10A,RPL29,KPNA1,RPS15,RPL23,RPS10,RPL39,RPS27L,RPS7,RPL26,POLR2B,POLR2F,RPS23,RPS11,RPL4,POLR2G,GTF2F2,RPS12,RPS2,RPL27,RPS9,POLR2L,POLR2D,RPL7,UBA52,RPL37A,DNAJC3,RPL12,NUP50,RPL31,RPL9,RPL18,RPS3,RPL17,RPL22,RPL19,RPL10,RPL35,RPL26L1,RPS5,RPL8,RPLP2,RPS28,NUP153,RPS17,NUP62,RPS26,RPL15,RPLP0,RPL13A,RPS29,RPLP1,RPS4X,RPS27A,NUP35,RPL27A,RPL10L,RPS13,GRSF1,NUP37,RPS20,RPL6,RAN,RPSA,FAU,RPL32,CALR,RPL3,RPS16,RPS24,RPL24,POLR2C,RPL35A,GTF2F1,RPS14,POLR2I,NUP42,HSP90AA1,NUP107,RPL7A,XPO1,RPL28,RPL23A |
| 1.421e-10 | -22.67 | FAM20C (FAM20C golgi associated secretory pathway kinase) | protein interactions | 56975 | 188 | 94 | 19454 | 5460 |
PIGK,BST2,GLT8D2,ZMPSTE24,VMP1,SERPINH1,STK26,TAPBP,P4HA2,EEF1G,TOR1AIP2,TANK,WDR77,SEC62,YIPF5,MAP2K1,FDFT1,ARCN1,ANXA7,TCP1,PCSK9,PDIA3,DDRGK1,QPCTL,CRTAP,FKBP4,BPNT2,ST3GAL4,AHSA1,GPAA1,HSPD1,PDIA6,RUVBL1,SACM1L,PFDN1,TOP3B,ARFGAP1,ERLIN2,GDI2,RPN1,PLD3,ALG2,INPP5K,ALB,SEC61A1,GANAB,YES1,ZNF622,CSK,RETSAT,DNAJC10,CALU,ATP1A1,APMAP,SQSTM1,MTDH,CLU,HSPA5,TMEM106A,PICALM,HSP90B1,TRIM68,P3H1,EPHX1,SYNCRIP,GLT8D1,PTPN1,STT3A,XXYLT1,CAND1,TMPO,FAM118B,FAM20C,CALR,HM13,ESYT1,POR,DLG1,EHD4,ERO1A,STX18,B4GALT7,ERLEC1,GALNT2,RIGI,SMN1,EDEM2,CCDC47,PREB,TOR3A,TAF1D,LBR,TMEM165,HSPA13 |
| 1.421e-10 | -22.67 | SNAP23 (synaptosome associated protein 23) | protein interactions | 8773 | 188 | 94 | 19454 | 5460 |
CUL3,HNRNPAB,RAB11A,MYC,RHOB,LAMTOR1,RIT1,SCFD1,MATR3,ESR2,BET1,PTAR1,CLDN4,DUSP22,VAMP1,RND2,FAM3C,RAB5A,PMAIP1,EMC1,HSCB,FXR2,ZDHHC17,STX7,RAB5C,LAMP2,CTNNB1,RHOG,CBL,STX1A,SRSF1,RAB35,STX5,GJA1,RHOH,CHMP2A,VAMP7,DIRAS3,RAF1,SOX2,SNAPIN,CHMP4C,RAB4A,VAMP2,RND3,STX12,COX8A,KRAS,FLOT1,VAMP8,VAMP5,RAB2A,USP14,DNAJC5,STXBP6,NAPA,CTNNA1,SCAMP2,VAMP3,YES1,RHOJ,CEP97,CFTR,CDC42,WWP1,RPA2,PTP4A2,ARL15,PRKCA,RPA3,RHOU,SQSTM1,RAB9A,ELOF1,CERS2,HSPA5,DPP4,HDAC6,LAMP3,SYNCRIP,HRAS,RAC2,ARF6,CAV1,LMAN1,STX6,SNAP29,ILF2,SNAP23,STX18,ABCE1,RAB3B,TOLLIP,STX11 |
| 1.429e-10 | -22.67 | endoplasmic reticulum | cellular component | GO:0005783 | 2051 | 721 | 19108 | 5553 |
EVA1A,PIGA,NT5C3A,JKAMP,CYP2C8,SEC22B,PROS1,IL2RG,EMC10,CYP21A2,HSD17B3,FKBP8,PTPN1,TPD52,RPS7,CCDC134,YIPF4,IFI6,HCRT,PRDX4,TRAF2,KDELR1,MYRF,FATE1,PGS1,BOK,VTI1B,ACER3,RAB18,CYP1B1,CHP1,CYB5R3,LRAT,RNF121,FDFT1,ABHD4,SERPINA1,RDH11,CLN8,PIP4K2C,SELENOK,BCAP29,TRAM2,F9,GABARAPL2,CAPN2,RAB14,PSEN1,ALG11,CYP2D6,ESYT1,FBXW7,CLEC18A,HSP90B1,OPRM1,NSG1,EEF1B2,AGTRAP,TEX264,CAMK2G,TOR1AIP2,IFIT2,TSPO2,SLC30A7,TXNRD3,INSIG2,SSR1,PGAP3,SFTPA1,ANXA7,CST3,GOSR2,VEGFA,RNF5,NFE2L1,TRAPPC6A,GRIA2,CLSTN3,CYB5R4,OS9,CYP3A5,TAFA1,ERP29,RNF103,GRIA1,HPS6,OSBP,SERPINC1,TMEM147,RDH12,UFD1,RAB1B,P4HA2,TMEM30A,PHTF2,SSR2,CLDN14,BAK1,PLEKHF2,UBIAD1,PLAAT3,PRSS23,ELOVL6,TOR4A,ARL6IP5,C2CD2L,TRAPPC2L,CYP2C9,GJA1,EXT1,SELENOM,ZDHHC15,CCDC3,FSTL1,F10,DHRS3,ADIPOQ,CCDC47,TLCD3B,PCSK9,SPCS2,ATP8A1,UBXN10,RNF133,DHRS1,IL12B,GGCX,MSRB3,AHCYL1,WASL,AGA,CD59,CYP3A43,NDUFB8,MLC1,SRPRB,RPS3,NSDHL,FOLR1,ORMDL3,CTTN,LDAH,SCFD1,FMO2,TMX4,USE1,PREB,TRAM1L1,SRP72,CLU,LACC1,YKT6,GHRL,HACD2,SLC51A,MTMR6,ERO1A,CYP2F1,FURIN,GALNT2,RER1,EDEM2,SLC35B4,EHD4,SDCBP,SHISA2,TSPO,RTCB,SRXN1,IFI27,HSPA5,SRD5A3,TAS2R16,DHRS7B,VAPB,HACD1,FKBP2,ERG28,CYP26A1,SMPD2,UBA52,EIF5A2,SLC37A4,RNF128,SYVN1,RIC3,CD1C,PIGC,CRHBP,B2M,NKIRAS1,DNAJB9,CD4,ERLIN2,LPCAT3,KCNIP3,EI24,ATG101,JPH4,HMOX2,COPE,FAM20C,TMEM14A,GABBR1,MEST,SLC39A7,TPBG,TMBIM6,CAMLG,KCNG3,TRAPPC1,ASB11,DLG1,SIGMAR1,TMCC2,PSENEN,CYP2R1,ALOX5AP,MGAT4B,GSTM2,PRKCA,FKBP1A,TLR8,GLUL,DAG1,DUOXA2,G6PC3,VAC14,DLG4,CH25H,FKBP1B,CYP4F8,RAB1A,P3H1,TMED3,ZFAND2B,DNASE1L1,FMO3,FKRP,CRABP2,CHRDL1,BCL2L1,COL1A2,RPL24,ALB,FIBIN,RETSAT,UBXN2B,INPP5K,RPL4,RPL18,ATP2C1,KCNA2,ACO1,MTDH,SRPRA,SERPIND1,RPL10,MAP2K1,RPS23,OST4,ATL1,VKORC1L1,RPS27A,DEGS1,PDE2A,SQSTM1,EMC8,TUSC3,SCG2,TEX261,DIPK1A,ZDHHC14,UBB,CTSA,AGR2,IL15RA,FADS2,SLC39A13,SEC23A,XBP1,IL12A,SLC1A1,CNPY3,GANAB,PSKH1,SDF2L1,NUS1,CERS2,PDIA2,TFG,STX17,DIO1,STX8,PLD3,MAN1A2,CSH1,SEC13,HRAS,ATP1A1,TLR3,LMBR1L,GPAA1,EXTL2,PGRMC1,AGPAT1,TMEM170A,TMEM50A,POMT2,PEDS1,SEC61A2,TMEM117,FIS1,RAB9A,HTRA2,SGMS2,TLR9,TRAPPC3L,RGMA,NPTX1,FKBP14,TM4SF20,CNIH1,ACSL4,IGFBP3,APH1A,HM13,DHRS4,LYPLA1,HSPA13,RPS24,TMX2,CRTAP,KRAS,RASD1,STARD4,AQP11,VCPIP1,TFPI,PDIA6,KCTD17,WNT7A,SLC35D1,RPL27A,POR,CD1D,BFAR,LYNX1,AGPAT5,SELENOF,UGT1A1,CYBC1,BAX,ERLIN1,GNAI3,SFTPD,TMT1B,KIF1C,LAMB2,ABCB9,SFTPC,FKTN,VWF,CREB3,EEF1G,PDIA3,RPN1,GPR85,CDNF,CYP17A1,MX1,DNAJC3,DBH,EDEM3,ZDHHC24,PYCARD,TMEM100,PTDSS1,TICAM2,RPS26,FAM8A1,MZB1,HSD17B6,BNIP3L,SPCS1,ELOVL7,LGI1,PTGDS,SNX10,ARHGAP5,TAPT1,FA2H,PCYT1B,RPL27,BSCL2,SEC22C,KPNA2,SEC61G,GDPD3,DERL1,SPTSSB,SCG3,UPK1A,FLRT2,RETREG1,SLMAP,WDR83OS,ZDHHC16,FAF2,TAPBP,MGAT4A,ATP1A2,PTN,TRAM1,STX18,TRAPPC3,TMEM33,GALNT1,F7,STIM1,LBR,SDC2,SYNCRIP,SEC61A1,ARCN1,XXYLT1,CARD19,RNF139,CYP4V2,AMELX,CYP1A1,LRP6,PLP2,CREG2,NOS1AP,UBAC2,NLRP3,HYAL2,NCSTN,KLK6,ALG2,FAXDC2,TMED4,MRLN,IZUMO1,CYB561D2,SPCS3,CRAT,MACO1,LMBRD1,EMC4,SEC63,TOR1B,VAMP7,FITM2,LRRC8B,DRD1,FITM1,ERLEC1,FOS,CYP39A1,CYP4F12,RDH10,MSMO1,IGFBP4,TLR7,DNAJC25,RNF122,TRIM32,FLRT3,PSEN2,SPON1,TOR3A,STBD1,TMEM39A,TMEM38B,ELOVL4,RPL10L,BACE1,PML,ILVBL,TMCC1,RETREG3,TMEM97,PNPLA8,KDSR,THY1,SLC35A2,RB1CC1,MINAR2,VMP1,SERINC1,GABARAP,RNF115,GABARAPL1,NPC2,RP9,ELOVL3,SRI,PRNP,REEP6,TOR2A,STUB1,OPRK1,GORASP2,SLC35B3,HSD17B11,MOXD1,UTP15,TRAPPC6B,LRRC8D,MYORG,DERL2,TSPAN5,RAB6A,CIDEB,LRRTM1,TMT1A,PIGW,RSAD2,CYP4F22,SEC11A,ZDHHC4,EMC1,UFM1,GIMAP2,STT3A,EMC6,REEP4,SEC22A,RAB32,RNF148,STX5,CHRM3,UBE2G2,RNF41,SAR1B,CALU,RNF26,SRP54,PITPNB,TIMP1,CLDN8,MARCHF5,PEX3,TMEM203,OAS1,TRIQK,MPIG6B,CGRRF1,SPTSSA,CASP12,SEC61B,TSN,CBLN3,FKBP10,DMPK,TXNDC12,PRKCE,RANGRF,HACD4,CDK1,PIGK,RPS29,SVIP,ATP1A3,RNASET2,FGF23,DNAJB2,IL23A,GJC1,CREB3L4,CYP2C18,AHSA1,CYB5B,KDELR2,FZD6,LMAN1,UFL1,YIPF5,TMEM50B,PIGY,TRAPPC4,REEP3,DNAJC1,ACAT1,CAV3,TESPA1,BET1,PYURF,GPX7,YIF1A,NCK1,HACD3,EPHX1,TMED1,TMED9,STOM,TMEM199,CDC42,TMEM208,CAV1,SCD5,PLN,JAGN1,MGST3,VASH1,ORMDL1,TMED5,PPIB,COL3A1,JMJD8,BECN1,EMC2,RHOG,PLPP6,MBLAC2,HSD11B1,TF,TMBIM1,DNAJC10,RCE1,RBMX2,RHEB,DAD1,RAB2A,MAMDC2,ABHD12,DOLK,TP53,RAC2,SSR3,DHRS7,DPM2,CTSC,OSBPL8,COPZ2,STAU1,SGMS1,ZMPSTE24,PTGES,SELENOS,PTPN5,DPAGT1,ELOVL1,MPDU1,ALG5,PGAP2,ZFAND2A,CASP4,GJB1,TMEM106C,BGLAP,RPS28,RPL6,ATG9A,CERS6,ATP6AP2,FAF1,RINT1,SC5D,ESD,RETREG2,SPHK2,MOSPD1,PDE9A,GPR37,SPPL3,FMO1,RRAS2,DDRGK1,CDIPT,MGST2,CYP7A1,EMC9,SDR16C5,NOTCH2,OTULINL,APOO,LRRC8C,HMGB1,SPP1,CFTR,SELENON,CALR,TMEM174,TECR,SERPINH1,TLCD4,SELENOT,TSPAN15,RPLP0,SLC30A5,PROM1,ANP32A,IL6,EDEM1,CYB5A,HAX1,CHI3L1,SURF4,MTMR12,TMX3,TMED7,STARD3NL,CNIH4,NDFIP1,SEC62,POMP,ARB2A,CYB5R1,TAB1,APEX1,RTN4,PIK3R1,MIA2,TAPBPL,SELENOI,F2,SACM1L,GNAZ |
| 1.481e-10 | -22.63 | response to biotic stimulus | biological process | GO:0009607 | 1408 | 521 | 18204 | 5365 |
NMI,TXNIP,CLEC6A,IFI27,SIN3A,RIGI,LYAR,LDOC1,CD36,TPT1,HP,CD80,RBBP9,CDC42EP4,PMAIP1,POLR3F,OPTN,OCIAD2,SH2D1A,JAK1,WFDC5,SYNCRIP,EXOC1,LEAP2,MGST2,TNFRSF1B,TLR9,PCK2,ATG7,IFNK,EEF1G,DNAJC3,FABP4,CXCL3,CDC73,IFNA2,MIR21,LILRA2,DHX16,AQP4,DDX1,FCER1G,MX2,IL12B,TREML1,FGR,POLR3B,RNASEL,RNASE6,G3BP2,MIR223,FOXP1,CXCL9,IFNA10,LSM5,PYDC2,CD86,MMP9,RSAD2,IL6,GTF2F1,PI3,BAX,RTP4,MATR3,TMED1,CD274,FOXP3,MX1,ENO1,VPS26B,TRIM34,DAPK3,CXCL14,RPL39,IFNGR1,ST13,PELI1,TIRAP,MIR187,STAT1,ACP5,BST2,LYZL6,JAK2,STXBP1,BCL2L1,RAB27A,DIO2,DEFB114,KRT8,MIR545,PRKCE,LACC1,TUBB4B,CD14,EIF2AK2,TOLLIP,XBP1,CDC42EP2,CREBZF,RPL13A,TMEM229B,CNR1,KLRD1,UBE2N,MIRLET7B,PLAA,MIR130A,PAK2,CALR,GRPR,FBXO9,MIR675,PPP1R11,UBE2W,EP300,ROMO1,NFKBIA,GPX1,TMEM106A,CCL24,CXCL11,HYAL2,GSTP1,BAK1,MIR95,TNFAIP3,IL1B,AKT1,DEFB129,CEBPE,ZMYND11,SELENOS,TANK,ISG20,TLR6,IFNA13,MECP2,ALPL,IVNS1ABP,MIRLET7I,TICAM1,TLR1,BNIP3L,LYZ,SAMHD1,IL23A,CCL1,IRF1,PQBP1,TRIM10,CCDC47,ACTR2,BPIFB1,CAPN2,CCT5,TLR8,NDUFAF4,IFI16,OPRK1,IFNG,TAB2,FAU,SERINC3,CD47,IL17F,LGR4,CAMP,TMEM45B,PRKRA,PDCD4,TRIM35,SRC,NT5C3A,IL18,PRDX1,EXT1,FASLG,RNASE4,REG1B,PIK3CG,PDE4B,TFEB,TRIM21,MIR140,CD58,ZNF175,COTL1,PHB2,HEXIM1,TUBB,PML,CCL2,PSPC1,SEMG2,FOS,TASL,CCL4L1,KCNJ8,NFKB1,ARG2,RNASET2,TICAM2,TLR10,TRAF6,TLR2,RARRES2,THBD,APOBEC3A,CD2AP,CDK4,XRCC5,CYRIB,TRIB1,TBK1,BPGM,TLR5,VAMP3,CCL19,SFTPD,SMAD3,RNASE9,ATG16L1,SARM1,LGALS8,IFIT2,CD2,LACRT,YES1,NPC2,TRIM62,PLSCR4,TUSC2,GPAM,KLRC2,DEFB115,TRIM32,CD40,RAB14,CCL23,OTULIN,WDR83,CCR4,NLRP1,SYK,CLU,CH25H,STAP1,TRIM5,APOBEC3C,S100A8,FCGR2B,NFKBIL1,MAVS,IFNB1,TRIM11,CAV1,TYROBP,CHID1,NCR3LG1,POLR3H,MEF2C,MSRB1,RAB1A,TAX1BP1,PIM2,ODC1,ZYX,MYD88,MIR421,MIR342,SNX3,HSPA5,IRF9,GFI1,SLPI,ZMPSTE24,IFIH1,MIR146A,TRIM26,PLPP6,NLRP9,CD4,CLDN1,CCDC186,RNASE1,CD46,APOBEC3F,AKAP12,DEFB124,TRIM68,TLR3,G3BP1,CCL5,CNPY3,MIR142,APOBEC3G,HSPB1,PRDX3,IFNAR1,CDC42,DAPK1,IER3,PTGER2,CCL17,ELMOD2,SAP30BP,LILRB1,MOV10,PELI3,IL12A,REN,BCL10,BPIFB3,CCL3,APOBEC3D,MIF,CFL1,AKAP1,TNFSF8,HSP90AA1,STX8,IRF3,CSF2,TMEM255A,TRIM29,DHX15,USP14,NLRP6,H2BC11,TLR7,IRF7,OAS1,CCDC92,FCGR1A,REG1A,CHGA,IRF8,SHC1,MRC1,HDAC5,MAP3K14,FOSL2,LTA,STAT2,CCR5,FAM3A,HNRNPA0,EXOSC4,MIR20A,CYBC1,CCL21,TRIM22,LITAF,CYP1A1,BANF1,ATP1B1,IFI35,BECN1,FCN2,CLPB,IL1A,MAP2K3,CD209,ACTA2,PLSCR3,SRPK2,NOTCH2,IL18BP,TRIM8,NCK1,JAGN1,TF,LIAS,RAB29,DEFB116,DEFB1,GJB2,FGF10,C1QC,TTC4,DHX9,VAMP8,FMO1,WASL,NFKBIB,PTPN22,IRF2,HCFC2,CREBBP,CCL20,JCHAIN,CXCL1,MTDH,WFDC13,CST11,CCR7,DDIT4,ISG15,UAP1,TRIM15,SDHAF4,CNOT7,IKBKB,IL34,RBCK1,GPM6A,GAPDH,CYP27B1,SLC17A5,EPO,LGALS3,DROSHA,B2M,YTHDF2,CHMP5,IRAK4,TNFAIP8L2,TRIM52,TSPO,NQO1,APOBEC3H,PTGER4,LYG2,SLC15A2,PPARG,CXCL13,SPAG11B,TP53,ARF1,IDO1,LYZL4,RGS1,CXCL8,CNP,H2BC12,IL13,ENDOD1,SOD2,AZI2,IL21,CLEC7A,BPIFA2,MIR26B,PRDX2,UGT1A1,TMEM33,DDIT3,TRIM27,SEC11A,IFI6,TLR4,SEC14L1,NONO,CDK6,CCL8,TOMM70,CCL11,KLF4,APOBEC3B,MIR105-1,LRAT,LSM14A,CXCL10,TNFRSF14,VAMP2,NLRP2,CITED1,TRIM23,CGAS,PTGER1,CCL18,CASP4,CEBPG,NLRP3,CCL25,MIR17,PPM1D,FBXO3,MAPKAPK3,PDCD1LG2,PLSCR1,IRF4,TIFA,F2,AIF1,CLDN3,RBPJ,PTGFR,IL10,XCL1,RAF1,CX3CL1,PLAAT3,ADIPOQ,TNF,DEFB121,LY96,TRIM6,PHB1,VAMP7,PSMA2,PDE12,TRAF2,CX3CR1,NMBR,EPHA2,PLAC8,CXCL12,MBL2,HMGB1,CD1D,IL1RAP,DUSP10,BATF,HRAS,PYCARD,RNF5,ITGB8,CXCR4 |
| 1.483e-10 | -22.63 | SNRPC (small nuclear ribonucleoprotein polypeptide C) | protein interactions | 6631 | 420 | 178 | 19454 | 5460 |
HNRNPA1,TRA2A,ZNF207,PRPF19,HNRNPD,DDX23,SKIC8,THY1,IFIT2,BOLL,PHB1,SRSF10,NUP35,WDR37,POLR2D,POLR2C,SNRPE,NGB,SRSF8,FHL3,ARGLU1,HNRNPA2B1,SRSF4,PPWD1,SSRP1,DHX16,TOMM40,PRPF31,RIOK2,CUL2,CUL3,DCAF4,SNRPD1,SNRPD2,ZMAT2,CPSF1,ERH,SNRPB2,KRTAP8-1,SUPT4H1,WDR77,MFAP1,AGGF1,USP39,PSMA3,FAM168B,COIL,APOBEC3F,MOV10,NCBP2,ZBTB2,CWC15,DCUN1D1,KLF1,TOP1,THOC1,CD2BP2,APOBEC3D,DDX39A,EXOSC8,TBK1,NDUFA2,ILF2,POLR2G,ZC3H11A,PQBP1,SNRPG,SMN1,LSM4,CTNNBL1,THRAP3,RUNX1,MGAT5B,CDC73,NCKIPSD,MRPL53,UFSP1,METAP2,EIF4A3,TXN,ATG16L1,RBFOX2,TXNL4A,SF3A1,WDR83,SNRPN,TOX4,LSM2,STOM,KIN,PPIH,RPA3,PRPF4,WWP2,TNNC2,MAGOH,WDR82,POLR2L,SRSF1,HNRNPL,SNRPA1,SNRPD3,LSM5,SUPT5H,ODAM,SMNDC1,EWSR1,TRIM11,FAM168A,CMTR2,RERE,HNRNPDL,KRAS,HNRNPF,SNRPB,CPSF2,MYC,HNRNPC,HNRNPAB,CHTOP,SMU1,SF3B4,POLR2B,MATR3,SNRNP40,ZC3H14,NCOA5,RAMAC,DDX5,SNRPA,ACTMAP,DDX39B,RPP14,SAP18,TRA2B,HNRNPA0,STAU1,CD81,COPS5,ANKRD10,AKAP8L,SNRNP70,GNPAT,SYNCRIP,ALYREF,DKC1,CDC5L,FZR1,CAND1,NKAP,NUPR1,DDX42,IK,DHX9,NEDD8,CDC40,SRPRB,SUGP1,MORF4L1,IGF2BP1,RBM7,UBE2H,LSM6,RC3H2,GEMIN8,SF3B6,PPP1R10,SRPK2,PPP1R8,HEXIM1,LUC7L3,RPRD1B,WRAP53,RPA2,ZNF326,HNRNPH2,BAP1,RBM22 |
| 1.494e-10 | -22.62 | SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide) | protein interactions | 6632 | 318 | 142 | 19454 | 5460 |
ELK4,WDR77,PIH1D1,EIF4B,EP300,DDX5,HSPA8,SF3B1,DDX39B,SNRPA,STAU1,UFL1,UCHL3,SRSF2,SNRPB,PRPF31,CUL3,CUL2,MYC,RIT1,H1-1,ICAM1,LMNB1,CKB,PRMT5,SNRPD2,SF3B4,MAD2L2,ESR2,APEX1,SNRPB2,ACTB,LGALS3,SNRNP40,RPS7,E2F4,SUPT5H,RAF1,SNRPE,ZRANB2,SF3B5,SMNDC1,CHMP4C,NGB,EZH2,SRSF7,EWSR1,HNRNPA2B1,HSPD1,SSRP1,RUVBL1,PTPN4,G3BP1,KRAS,CTNNB1,DDRGK1,HNRNPA1,DPY30,ASB1,PRPF19,MAGOH,YWHAB,AGR2,DDX23,EED,PHB1,IFIT2,SRSF1,DHX15,HSP90AB1,NUP35,SNRPD3,SNRPA1,HNRNPL,SNRPN,SF3A1,HEXIM1,UBE2M,LSM2,METTL14,RPA2,LMNA,RPA3,BAP1,DDX46,LSM8,HSPA5,FBXW7,PDHB,RUNX1,TIA1,UBE2H,PDCD4,RC3H2,LSM6,SPOP,PTEN,EIF4A3,CCNF,SF3B6,NMI,BCCIP,VIRMA,SRPK2,SMURF1,FERMT2,TMOD3,NDN,DDX39A,EEF1A1,CD2BP2,NUPR1,GEMIN7,ILF2,DHX9,RAB27A,SNIP1,SMN1,RIGI,PTGES3,SNRPG,MEPCE,HNRNPK,TSSC4,NEDD8,LSM4,API5,COPS5,CD81,RBM17,LSM3,SNRNP70,CRBN,LDLR,SRP14,CWC15,CDC5L,RBM42,PRNP,TOP1,CAND1,DCUN1D1 |
| 1.504e-10 | -22.62 | APC/C:Cdc20 mediated degradation of mitotic proteins | REACTOME pathways | R-HSA-176409 | 76 | 51 | 10285 | 3229 |
PSMB9,SEM1,PTTG1,ANAPC4,PSME2,UBE2D1,PSMD6,ANAPC2,ANAPC15,PSMB4,CDC23,RPS27A,PSMD4,CCNA2,ANAPC11,PSMC3,PSMA1,ANAPC16,PSMD12,CCNB1,PSMC1,PSMD1,PSMB2,MAD2L1,PSMA6,PSMD7,PSMD10,CDK1,PSME1,CDC26,UBA52,UBB,PSMD14,NEK2,PSMB5,PSMA3,PSMC4,PSMD3,CDC16,PSMB7,CDC20,PSMB1,PSMA2,PSMB6,BUB3,PSMB3,PSMA4,PSMB11,PSMC5,PSMA5,PSMB10 |
| 1.510e-10 | -22.61 | LOXL2 (lysyl oxidase like 2) | protein interactions | 4017 | 400 | 171 | 19454 | 5460 |
CSE1L,DHX9,RPL3,ERO1A,IK,TFRC,RPSA,RPS16,MYL12A,UBE2N,SSBP1,ELSPBP1,SYNCRIP,H2AC4,MAP4,KARS1,TPM3,GAPDH,GPIHBP1,HSPA5,TXNDC17,RPL27,LCP1,PGK1,HBB,H2BC11,GSTP1,CAPN1,SPTBN1,DAPK1,IDE,UQCRC2,MACROH2A1,CALML5,CMA1,MRPS16,ATP1A1,OAT,RPL7A,SMARCA5,RPS4X,TOP2B,CCT8,PABPC1,ABCF1,RPL31,TMEM87A,MYO1B,PLS3,RPS23,NCR3,RPL18,PI15,TCP1,SNRPD3,HNRNPL,CCT7,FABP5,S100A8,HSPB1,RPL6,DIRAS2,FXR2,TMEM106B,LCN1,EIF4B,RPL27A,TRIM29,ATP5F1B,VDAC2,CCT2,RPS26,SFN,HNRNPAB,HNRNPC,MYC,PSMD1,TF,THRAP3,RPS13,RPL23A,MAGEA4,ILF2,PGM1,GGCT,TOP1,RPL35A,SLC25A12,SRP14,EFNA3,ALDH1A3,H2AZ1,EIF5A2,CALR,RPL4,CSTB,WNT7A,H2BC12,CST11,HSP90B1,RPLP0,RARS1,RPS14,UQCRC1,TMOD3,MAGOHB,TXN,RPL22,ENO1,CTTN,MSN,ALB,RPS20,RPS12,GANAB,SDF2L1,STK11,CTSD,ATP5F1A,FBXO7,SSRP1,HSPD1,SLC25A5,RPS24,GDI2,RPN1,RPS11,FEN1,TULP3,ERLIN2,RPL29,ACTN4,PPP2R1A,RPL7,DNAJB9,DHX15,OS9,PPIA,ERLIN1,PSMB4,RPL8,RPLP2,PPM1B,CSTA,RPL23,HNRNPD,LYZ,CFC1,PRDX1,PSMD3,PDIA3,AZGP1,CDSN,HADHA,MYL6,H1-5,WDR77,RPL35,PRDX2,SNRPD2,SNRPD1,BRCA1,LMNB1,YWHAZ,TAFAZZIN,HSP90AA1,KLK5,ACO2,NIBAN2,GGH,MCM3 |
| 1.521e-10 | -22.61 | Influenza Viral RNA Transcription and Replication | REACTOME pathways | R-HSA-168273 | 137 | 79 | 10285 | 3229 |
NUP42,POLR2I,RPS14,GTF2F1,RPL23A,RPL7A,RPL28,NUP107,HSP90AA1,RPL24,RPL35A,POLR2C,RPL3,RPL32,FAU,RPS24,RPS16,NUP37,RPS20,GRSF1,RPSA,RPL6,RPL27A,NUP35,RPS27A,RPS13,RPL10L,RPS29,RPL13A,RPLP0,RPS4X,RPLP1,NUP62,RPS17,RPS28,NUP153,RPL15,RPS26,RPL8,RPS5,RPLP2,RPL19,RPL26L1,RPL35,RPL10,RPL17,RPS3,RPL22,RPL18,RPL9,RPL31,RPL12,DNAJC3,NUP50,POLR2D,UBA52,RPL7,POLR2L,RPS9,RPL37A,RPS11,POLR2F,RPS23,RPS2,RPL27,RPS12,GTF2F2,RPL4,POLR2G,RPL39,RPS10,POLR2B,RPL26,RPS27L,RPS7,RPL29,RPL10A,RPL23,RPS15 |
| 1.543e-10 | -22.59 | regulation of catabolic process | biological process | GO:0009894 | 1124 | 427 | 18204 | 5365 |
PRKCA,MIR214,STK38L,AZIN2,PSME1,RAD23B,CASC3,PIP4K2C,EXOC8,MIRLET7C,PSMD14,HSPB8,CAPN1,SUPT5H,TENT5C,PSMD10,TMEM39A,SH3GLB1,RNF152,DAP,MIR424,SLC25A5,TRIM23,CTTN,HMGB1,YTHDF1,MIR495,ORMDL3,STUB1,DFFA,HFE,VPS28,CDK5,LARP4B,MIR98,FBP1,RNF5,ABHD5,OAZ2,GTPBP1,MIR23A,PYCARD,PLEKHF1,PSMD3,DDRGK1,TNF,ATP6V0E1,IL10,ROCK2,SLC25A4,MIR191,TRAF2,MIR145,PDE12,TRIM6,PHB1,GABARAPL2,HECTD1,TSPO,KLHL22,BTG2,NQO1,DCP2,COP1,CDKN1B,MIR193A,SESN2,MIR106A,SUFU,UFL1,DESI1,MIR212,SCFD1,CCDC22,PSME2,CSNK1A1,SGTA,RAB39B,RPL23,RNF139,DET1,WDR6,TGFB1I1,GAPDH,CNOT7,APOC2,FAF1,MIR195,YTHDF2,FBXO22,CNOT8,MIR340,MIR26B,TIMP4,BAG2,ADORA1,PTPN1,TRIM27,DDIT3,CCNY,RRAGA,MDM2,GNAI3,FKBP8,TENT5D,TP53,MIR1-1,LEPR,FHIT,OAZ1,ATG101,TRIM22,AZIN1,CSNK2A1,CIRBP,HNRNPA0,RGN,MIR20A,BAG3,TMEM168,NDFIP1,RHEB,SOX9,BECN1,CISD1,CNOT6,MIR200C,ATP2B4,USP14,MAD2L1,NLRP6,MIR708,ZC3H14,HGS,SUMO1,IDH1,HNRNPC,USP13,GCLC,ATP6V1C1,PTPN22,DHX9,ATP6V1G1,SNX33,DDIT4,C9orf72,MTDH,ADRB2,SVIP,CRYBA1,ZFAND2A,MIR192,SESN3,SEC22B,TRIM8,MIR9-1,HTRA2,OPHN1,SOCS5,ZMPSTE24,MIR342,MYD88,SNX3,IL4,ALKBH5,MIR149,IDE,SNRNP70,CD81,MTM1,PSEN1,MIR146A,FASTKD5,CPTP,CAV1,IFNB1,ATP6V1A,RC3H2,USP8,FURIN,ODC1,VGLL4,PIM2,AGAP2,HSP90AB1,ZCCHC17,CAV3,USP5,MIR190B,HTR2A,MOV10,SOCS4,ETFBKMT,HSP90AA1,ATP6V1D,WDR45,CDK5R1,MIR106B,CST3,ATP6V0B,TRIM68,ZER1,CSNK1E,RCHY1,TIMP3,FLCN,IER3,CDC20,DAPK1,FZR1,MIR142,NUPR1,AGO1,HSPB1,MIR181D,FXR2,MIR373,RARRES2,MYLIP,HCAR1,PIAS1,TBK1,TRIB1,TMEM59,VIP,FEZ1,IGF2BP1,PSMC5,PHF23,DISC1,PML,JMJD8,MIR491,MIR16-1,PABPC1,PSMC1,PITHD1,CLU,RALB,BOLL,POLDIP2,FBXW7,HDAC6,PRR5L,RPS7,STK11,CCAR2,TRIM5,ATG16L1,VSIR,SMAD3,MIR24-1,XPO1,ATRAID,RHBDD3,TAF9,TNRC6C,HNRNPD,TRIM32,EIF4A3,LAMP3,CNOT6L,PSMC4,LACRT,MIR625,ATP6V1E2,PIK3R2,MIR100,CUL3,BSCL2,PSMD1,IFI16,RGP1,METTL14,PRMT6,FBXO7,TICAM1,NFE2L2,MIR137,MIR181C,CTSA,BNIP3L,TIMP1,LYPLA1,EXOSC3,TNFSF12,NRDE2,MTMR2,RB1CC1,SH3BP4,ADRA1A,ASB11,SUMO2,PIK3CG,TRIM21,TFEB,MIR140,SQSTM1,LEP,RNF41,POLR2G,TENT2,MIR34B,STX5,DTL,PIK3CA,IFNG,APEX1,TAB2,ROCK1,OAZ3,MIR135B,TOM1,PHAX,MAGOHB,USP30,TSPAN5,MET,SNX12,MIR320A,MIR206,MIRLET7B,TRIM63,MIR130A,PSMC3,MIR497,HNRNPAB,CNR1,MSN,PTEN,MIR125A,TIRAP,TSPAN15,PCSK9,CDK5RAP3,GSK3A,PRKCE,EGLN2,BAD,RGMA,PARL,DEDD,ELAVL4,NOP53,AIFM1,AKT1,IL1B,RNF128,GABARAP,VPS26A,EXOSC8,SMAD4,MIR211,SNX5,DKC1,EP300,IGF1,MAGOH,CNOT2,SNX18,GRSF1,ATP6V1G2,PACSIN3,BOK,TNFAIP3,MT3,GPX1,TNFRSF1B,FMC1,TLR9,ATG7,SMURF1,SYNCRIP,EXOC1,MCL1,TSPAN17,AQP11,MIR96,DNAJB2,MIR21,MIR30B,MIR519D,MAD2L2,MIR204,MIR423,RRAGB,WNT10B,OPTN,MIR210,HP,IREB2,DXO,PRKAG1,VPS26B,TRIM34,AKT2,LDLR,MIR885,DRAM1,VDAC1,MIR130B,HAX1,CARHSP1,PAFAH1B2,EEF1A1,GPR137,TENT4A,PPARA,DAPK3,TRAF7,THRAP3,MIR223,RNASEL,PCBP4,UBE2K,MIR185,TBC1D25,UBE3A,EIF4E,BAX,TRAF3IP2,TP53INP1,USP38,IL6,PAIP1,CAMLG,UBB |
| 1.568e-10 | -22.58 | TRAF6 (TNF receptor associated factor 6) | protein interactions | 7189 | 426 | 180 | 19454 | 5460 |
KDM4B,RBCK1,TGFBR2,TOLLIP,STRADB,MYD88,ZBTB25,EDA2R,RPL3,TRAFD1,TLR3,PIK3CA,TAB2,PSMC3,SNAP29,UBL4A,TP53,H2AX,UBE2N,MCL1,TRIM45,BCL10,SMAD4,BECN1,RPS2,USP15,PLEKHO1,USP3,USP2,HDAC3,TOMM20,TICAM2,PSEN2,IRF3,HSPB2,PRDX6,RSAD2,SDCBP,ZNF326,FGFR1,WWP1,STAT6,KLF4,TRAM1,MAP3K3,SMURF1,SRC,TRAF1,PSMC5,TRAF7,SPOP,TLR9,TNFAIP3,CARS1,AKT1,PTPN11,PRKACB,DNAJC5,KRAS,PELI1,VDAC1,ABCF1,IRF8,CRTC2,TRAF2,KIF2A,RAB1B,PTK7,TNIK,IKBKB,CBL,IFI16,STK4,CTNNB1,UBE2D3,PEBP1,CD40,TIFA,STK26,MAP2K1,SYK,TANK,TIRAP,MATR3,PSMD6,TRIM29,TAX1BP1,DLG4,BEX3,PELI3,ST3GAL1,PSMD1,CASP4,PSEN1,TICAM1,SMN1,TLR4,HSD17B10,NTRK2,PPP4C,TBK1,EEF1A1,MAP1LC3B,SOCS3,DDX39A,UBE2V1,PLEKHF2,PRNP,TOMM70,CAV1,EIF4E2,MAP2K6,CRBN,PSMD7,ID1,KXD1,BMPR1B,IRF4,ATP1B1,ZMYND11,IRF7,GTF2I,TMUB1,MAVS,SQSTM1,TP53INP2,STAMBP,YES1,UBE2L3,UBB,STUB1,PELP1,CCNF,TNFRSF1B,EIF2AK2,GANAB,UBE2I,RPS20,TXNIP,LRP6,CSK,EMILIN1,TRAF3IP2,RUNX1,USP14,PPP1CC,TNF,TRIM37,RPS27A,PSMD12,IRAK4,MAP3K11,EZH2,PSMB5,PHB1,MAP1LC3A,KRT8,UBE2D1,PEDS1,RNF152,TRAF6,PSMD3,PRDX1,MARCHF5,HNRNPA1,MAP3K14,PSMC1,BIRC2,USP39,TAB1,UBTD1,JAK2,USP5,FAM177A1,SARM1,HTRA2,CUL3,PYCARD,IRF1,OTUD7B |
| 1.583e-10 | -22.57 | ERGIC3 (ERGIC and golgi 3) | protein interactions | 51614 | 335 | 148 | 19454 | 5460 |
SLC22A6,TMEM254,ENTPD3,TMEM243,CLDN8,PSEN2,ORMDL1,CCR4,LPAR1,TRAM1L1,SEC22B,CHRNB2,SYS1,SSR1,STOM,GPR35,CYBC1,SYNGR1,PTPMT1,SLC1A1,VAMP3,CDIPT,PLP1,CHRM4,TECR,VKORC1L1,CCR2,COPE,HMOX2,SLC35B4,TRIM32,VAMP5,GJB2,LPAR2,ERG28,UNC50,BSCL2,YIF1A,STX8,RUSF1,FKBP8,RIGI,NSG1,TF,ADIPOQ,YIPF4,UBIAD1,NRM,SELENOK,INSIG2,VAC14,SERPINA1,STARD3NL,COX20,EXT1,FA2H,SEC23A,RHAG,CNIH1,SLC25A17,FUNDC2,AIG1,VTI1B,TMEM107,HP,CD81,SLC41A1,ORMDL3,FAR2,SLC25A46,FAM20C,ZDHHC15,ADGRE2,BTN2A2,AQP2,TMEM42,DOLK,TMEM11,SLC35A1,TMEM203,EMP3,JAGN1,TMEM106B,PXMP2,RER1,TMUB2,CCDC167,TIMM29,VAMP1,CTXN3,TOMM22,GOSR2,BET1,AGTRAP,TMEM184B,FAM3C,SMCO4,LMBRD2,SEC61B,TMEM229B,S1PR4,GPR37,PARL,APEX1,THBD,NDUFB6,CYB561D2,PLN,FIS1,TMEM179B,FAXDC2,VMP1,TMEM100,ATP1A3,COX16,CYB561,GPM6B,TMEM147,TMEM87A,TOMM6,HS2ST1,TMEM60,PGAP4,YIPF3,MFSD6,NEU1,PGAP2,STX12,CYB5B,TMEM14B,VAMP2,RPN1,AQP3,CTSA,TMEM14A,TSPO2,TMEM97,CX3CL1,BUD31,EMC6,SYNJ2BP,PMP22,SLC38A7,MARCHF5,PPP2R5A,PLPP4,BCL2L1,FXYD6 |
| 1.583e-10 | -22.57 | PIAS1 (protein inhibitor of activated STAT 1) | protein interactions | 8554 | 335 | 148 | 19454 | 5460 |
PAX9,SNAI2,RPA2,LMNA,JUP,H2BC11,MX1,UQCRC1,SUMO1,RPS14,SPTBN1,HSPA5,PIAS1,RPS15,PML,RPL27,SPOP,PPP1CC,NONO,AR,RPL7A,AKT1,CSK,RPL22,UBE2L3,NR1H2,CEBPE,UBE2I,SGTA,RPS20,MACROH2A1,GANAB,TRIM27,CCNF,RPS3,CREB1,TFCP2,CBX3,SMAD1,RPL15,IKZF5,H2AX,TP53,RPSA,CDK4,RPL17,VPS16,MDC1,H2AC6,HNRNPK,TRIM63,H3C1,SEM1,CNOT7,DHX9,HSD17B10,RPL3,RPL23A,ZNF451,SFXN1,GLUL,SNIP1,ID1,LSM3,RPS2,SMAD4,ZMYND11,GAPDH,TPM3,CSNK2A1,MDM2,MYL12A,TOP1,RPS16,PTPN1,SSBP1,H2AZ1,MYL6,GTF2IRD1,PPARG,KLF3,FHOD3,SUFU,PHB2,MSX1,EP300,DDX5,TRIM5,HSPA8,RPS5,COP1,LMNB1,RHOB,BRCA1,YWHAZ,SFN,HNRNPC,OST4,HNF1B,CREBBP,ESR2,GRM8,DYNLL1,RPL35,SIAH1,TAGLN2,MATR3,STAT1,ZMYM2,ELK3,RPS11,HMX2,PLS3,RPS7,SOX2,JUN,RPL29,ACTN4,RPS4X,SATB1,LASP1,ZBED1,PDIA6,FHL3,PCNA,SLC25A5,RPL23,H2BC17,SIAH2,YWHAG,RPL6,HMGA1,PDIA3,SRSF10,PPIA,SUMO2,SPTAN1,MITF,TCP1,SUMO3,INA,PGR,TRIM35,HNRNPL,HP1BP3,TSG101,CORO1C,SRSF1 |
| 1.592e-10 | -22.56 | positive regulation of programmed cell death | biological process | GO:0043068 | 573 | 239 | 18204 | 5365 |
DAPK3,TRAF7,STK3,MTCH2,CDK5R1,CLIP3,MIR449A,PRNP,TMEM196,TPD52L1,LILRB1,CD274,IL12A,BCL10,HSPD1,HTR2A,MIR132,CCL3,JUN,PDCD5,RNF122,FRZB,MIR186,UBB,GADD45G,NUPR1,MIR107,CDC42,DAPK1,MMP9,BTG1,FLCN,SFRP1,IL6,BAX,MYC,TP53INP1,IL12B,AKAP12,MIR200A,TLR3,PEA15,ACVR1C,CCL5,FOXP1,MIR146A,PSEN1,ARL6IP5,MIR21,IGFBP3,MSX2,NACC2,MIR375,GADD45B,MCL1,TIA1,RGCC,ZBTB16,MYBL2,DNM2,TNFRSF1B,HTRA2,ATG7,CASP12,TNFAIP8,MEF2C,PMAIP1,MIR210,TXNIP,WNT10B,MIR204,IFNB1,CAV1,EEF1E1,SMAD4,RPL26,TLR6,TGFB3,AIFM1,CALHM2,PNMA5,NCK1,CTSK,HYAL2,VDR,BAK1,LTB,CTNNB1,BOK,CRYBA1,MIR675,TGFB2,PTRH2,CERS6,SRPK2,NOTCH2,CNR1,SOD1,LTBR,MIR221,PAK2,FIS1,UBE2M,BECN1,MLLT11,FAS,CTNNA1,HTRA1,MIR320A,BAD,G0S2,IRF8,PRMT2,TEX261,LTA,ING5,PCSK9,MIR125A,B4GALT1,JAK2,MIR29C,DDIT3,LEP,FASLG,CD40LG,SQSTM1,TLR4,ATF4,TFPT,MIR140,BACE1,TRIM35,PPID,CSRNP3,SRC,FAM162A,MIR26B,SAP18,TNFSF12,PNMA1,MIR15A,MIR34A,SOD2,CLEC7A,MIR1-1,PRKRA,ITGA6,PDCD4,CTSC,IFNG,TP53,ERCC3,STK4,IDO1,SERINC3,TNFSF10,LPAR1,EIF2B5,SFRP4,CAPN2,PPARG,PPP2R1A,BRMS1,CTNNBL1,TSPO,NQO1,MIR198,CCAR1,BNIP3L,MIR29A,CD248,FAF1,MIR195,SIAH1,RBCK1,PRELID1,MIR137,MIR28,CCAR2,PLEKHF1,RHOB,MIR23A,PYCARD,RPS7,S100A8,ATF3,MIR98,EMILIN1,FBXW7,NKX3-1,CDK5,KCNMA1,CD40,PNMA2,TMEM164,SAV1,PNMA3,BCL6,DFFA,STUB1,HMGB1,SYK,CLU,RPS3,PHB1,PDIA3,TRAF2,PDCD1,MSX1,IL10,MIR24-1,MIR101-1,ADIPOQ,TNF,MAP3K11,IFIT2,CTLA4,SYCE3,CTSD,ALDH1A3,CYP1B1,GADD45A,MIR17,CRADD,MIR16-1,EIF2S1,DCUN1D3,CASP4,ZNF622,CIDEB,CDKN1A,RBM5,PML,SPHK2,CCL2,DUSP6,NHERF1,BMPR1B,MAP2K6 |
| 1.602e-10 | -22.55 | Selenocysteine synthesis | REACTOME pathways | R-HSA-2408557 | 95 | 60 | 10285 | 3229 |
RPL23,RPS15,RPL29,RPL10A,RPL26,RPS27L,RPS7,RPL39,RPS10,RPS2,RPL27,RPS12,RPL4,RPS11,RPS23,RPL37A,UBA52,RPL7,RPS9,RPL12,RPL18,RPL31,RPL9,RPL22,RPL17,RPS3,RPL26L1,RPL35,RPL10,RPL19,RPLP2,RPL8,RPS5,RPL15,RPS26,RPS17,RPS28,RPS4X,RPLP1,RPS29,RPL13A,RPLP0,RPS13,RPL10L,RPL27A,RPS27A,RPSA,RPL6,RPS20,RPS24,RPS16,RPL3,RPL32,FAU,RPL35A,RPL24,RPL23A,RPL28,RPL7A,RPS14 |
| 1.607e-10 | -22.55 | Cyclin E associated events during G1/S transition | REACTOME pathways | R-HSA-69202 | 72 | 49 | 10285 | 3229 |
AKT1,AKT3,PSMA6,PSMB2,PSMD1,AKT2,PSMD12,PSMC1,MYC,CDKN1A,PSMD4,CKS1B,CCNA2,RPS27A,PSMA1,PSMC3,MAX,PSMB9,SEM1,PSMD6,PSMB4,PSME2,PSMB3,PSMA2,PSMB6,PSMC5,PSMB10,PSMA5,CCNH,PSMA4,CDKN1B,PSMC4,CDK4,PSMB5,PSMA3,PSMB1,PSMD3,PSMB7,UBB,UBA52,PSMD14,RB1,PSMD7,MNAT1,SKP1,CDK7,CCND1,PSME1,PSMD10 |
| 1.615e-10 | -22.55 | Prkaa1 (protein kinase AMP-activated catalytic subunit alpha 1) | protein interactions | 65248 | 94 | 56 | 19454 | 5460 |
IGF2BP1,HSP90AA1,MYO6,SPCS3,SNRPB,RPL26,RPL7A,TUBB,ACTB,ATP5F1B,RPS9,RPL37A,RAN,RPS3,MYL6,CFTR,PPP1CB,MYL12B,RPS14,PHB2,RPS15,DDX5,HSPA8,RPL27,RPL10A,RPL23,DRG1,RPS2,RPL24,TPM3,HSP90AB1,SNRPD3,RPS16,RPS10,PHB1,RPL8,RPL12,RPS11,ILF2,PRKAG1,TUBB4B,ACTR1A,EEF1A1,TUBA1A,RPSA,RPS4X,RPS13,RPL28,VDAC1,RUVBL1,RUVBL2,RPL23A,PABPC1,HNRNPA2B1,RPL31,SLC25A5 |
| 1.723e-10 | -22.48 | apoptotic process | biological process | GO:0006915 | 1038 | 398 | 18204 | 5365 |
PAEP,CSNK2A1,CTNNA1,BAG3,ERO1A,SOX9,TOPORS,BECN1,SNAI2,FIS1,DICER1,LTBR,CHST11,ADAMTS20,NCKAP1,MIR29C,ING5,LTA,FOSL2,PRKCB,CEACAM5,FEM1B,GLRX2,DDIT4,HAND2,ELMO2,KRAS,NOTCH2,CRIP1,PLSCR3,POLB,TGFB2,IL1A,PAK6,FGF10,SMNDC1,NUDT2,EMC4,HTRA2,ZMPSTE24,IFT57,MYD88,BRCA1,GADD45B,IGFBP3,ARL6IP5,PSEN1,RPS27L,CAV1,CDIP1,PIM2,CD28,TAX1BP1,MEF2C,EFNA5,TNFAIP8,PDCD5,HNF1B,BCL10,IL12A,CDK1,CNTFR,HEY2,IRF3,HSP90AA1,AKAP1,RNF34,DAD1,STK3,PEG10,TLR3,RMDN3,DYRK2,DLX1,MYC,SNCB,IER3,GGCT,MAGEH1,SFRP1,FLCN,PPIA,DAPK1,PLEKHO2,NUPR1,CRYAB,ZFAND6,PRKCA,NEFL,CXCR3,RNF144B,MIR17,XAF1,NLRP3,AIPL1,ALDH1A3,ARF6,EXOC5,GAS2,FOXC2,PLSCR1,MIEN1,BCL7C,PSMD10,INPPL1,CFDP1,SH3GLB1,RBM5,CDKN1A,ATG3,CIDEB,ZNF622,CASP4,RNF152,TNFAIP1,DAP,CITED1,ADNP,RB1,CTTN,NLRP2,BCL7B,DNAJC10,DFFA,MINDY3,EPHA2,ELMO1,CDK5,CXCR4,PYCARD,HRAS,RHOB,PLEKHF1,MZB1,TNF,CX3CL1,RAF1,MUL1,IL10,TRAF1,SLC25A4,MSX1,TRAF2,PDIA3,RPS3,EDA2R,HELLS,CDKN1B,STK24,LIPA,FATE1,CLN8,NR4A2,RAD21,CUL2,EPO,HINT1,GAPDH,SIAH1,FAF1,NCSTN,IL7,ITGAV,PRDX2,PCGF2,EMP3,ADORA1,CSRNP3,TMEM14A,DNAAF10,TFPT,JADE1,GHITM,EVA1A,IFI6,DDIT3,API5,MDM2,TNFSF10,BLOC1S2,RRAGA,STK4,ERCC3,TP53,MAEL,CTSC,FKBP8,MAP1S,MITF,FHIT,SOD2,DDX5,UBE2D3,SIVA1,XBP1,CD14,FAS,MLLT11,CAAP1,PAK2,MSH6,IL2,STK26,TGFBR2,SOD1,RRN3,CRKL,BCL2L1,STXBP1,JAK2,PTEN,PCSK9,CDK5RAP3,BLCAP,PRKCE,GSK3A,TMEM219,G0S2,KRT8,BCAP29,BAD,DEDD,TUBA1A,WNT7A,AIFM1,AKT1,DELE1,IL1B,SIAH2,GABARAP,SMAD4,NFKBIA,EP300,PTRH2,VDAC2,PDCD10,DIO3,SGMS1,NSG1,BOK,TNFAIP3,CTNNB1,SLC1A1,BAK1,NPR2,VDR,CTSK,CYFIP2,GPX1,KCNIP3,TNFRSF1B,EMP2,RTN4,ZBTB16,UBE2B,TIA1,MCL1,MSX2,SFN,MIR21,IFNA2,GPR65,ELK1,NOA1,IFI27,BCL2A1,EDNRA,BAP1,PMAIP1,CASP12,AKT2,PPP2CB,HSPD1,MX1,DRAM1,ERRFI1,VDAC1,TRAF7,PAK5,DAPK3,THOC6,PEA15,ACVR1C,TP53INP1,STAMBP,TRAF3IP2,BAX,IL6,AHCYL1,MMP9,ACAA2,RTKN,GADD45G,C1D,CD38,DMPK,CD2AP,GSKIP,ZDHHC16,TLR2,GADD45A,NDP,CYP1B1,NAE1,VPS54,SYCE3,PLAGL1,PPIF,NPTX1,MAP2K6,IL2RA,CHI3L1,PML,HINT2,NFKB1,KCNJ8,CRADD,CLU,NLRP1,BFAR,SAV1,RALB,ACVR1B,TMBIM6,NKX3-1,EAF2,S100A8,STK11,CCAR2,CD2,NAIF1,IFIT2,LMBR1L,SMAD3,CSRNP1,PARP2,GPAM,PDCD1,BIRC2,EGLN3,SELENOK,NR2E1,PIK3R1,CUL3,DNAJC5,BRMS1,IRF1,IFI16,AREL1,TNFRSF9,BEX3,NBN,TICAM1,MRPL41,PRELID1,IVNS1ABP,ARHGEF6,KDELR1,BMPR2,EI24,CD248,VEGFA,MIR29A,BNIP3L,PPM1K,CCAR1,TNFSF12,KCNJ11,FAIM,RB1CC1,SRGN,SST,FAM162A,ADRA1A,PPID,G2E3,TRIM35,ANGPT1,ZMAT3,ATF4,PIK3CG,RNF41,SQSTM1,PMP22,FASLG,BIRC5,TMEM117,TAF10,CD47,PIK3CA,DYNLL1,TCIM,IFNG,ROCK1,PDCD4,THOC1,MEF2A,ETV6 |
| 1.740e-10 | -22.47 | VHL (von Hippel-Lindau tumor suppressor) | protein interactions | 7428 | 558 | 225 | 19454 | 5460 |
NKRF,HUWE1,ADIPOQ,FASTKD5,TBK1,CCT5,SOCS3,PPARA,MAP1LC3B,EEF1A1,EXOSC8,APOBEC3H,POLR2G,RPL12,EIF4E2,PSMB1,DCUN1D1,TPSG1,POLR2I,MDM2,G6PD,ZNF200,APOBEC3F,SLC2A1,EIF5A2,MSMB,FBXO34,ID1,DVL2,RPA3,CSTB,SQSTM1,ITGA2,EGFL7,CHMP2B,RPS14,TPT1,P3H1,JUP,CDK1,STAMBP,RPLP0,MET,STUB1,CAB39,PRKRA,PTEN,UBE2I,ZBTB17,TXN,PDCD5,EAF2,CREB3,AR,RHOBTB3,TXNIP,IVNS1ABP,AKT2,ZYX,HNRNPA2B1,SELENOP,GUK1,RBBP7,ETFA,MSL2,FANCG,FLOT1,OTUD6B,SAP30,RWDD3,RPS11,POLR2D,STK16,KIF3B,PDIA3,PIK3R1,ATG9A,PRDX1,MAP1S,HNRNPA1,UBE2D1,CDK5RAP3,CSTA,PPM1B,RB1CC1,CDKN1B,HNRNPD,RNF139,SLC20A1,JADE1,PSMC1,TGFB1I1,FBXL4,CDKN1A,USP39,PPARG,VAPB,RNF7,MYL6,APOBEC3G,UBE2S,RPS9,ACTB,UMPS,RBBP4,JAK2,CUL2,CUL3,ZNF668,BRCA1,RPS5,PFDN4,SP1,HSP90AA1,PFDN2,PFDN6,RIT1,MAP1B,ADRA1A,TRAFD1,NEDD8,HNRNPK,FKBP8,CDK4,TP53,RPSA,CER1,CBX3,PSMC3,EEF1B2,SDHB,MRPS9,DSTN,CDK6,FZR1,RPS27L,MIF,MYL12A,SAT2,CSNK2A1,COPS5,ELOC,SNRNP70,TDRD7,RPS2,RPL10A,HNRNPH2,HDAC3,STK38,HSPA5,CLU,SUMO1,MPV17,WSB1,RPRD1B,PARD6A,KLF4,RPS3,MOB4,SMURF1,CSTF3,AKT1,CDO1,RPL7A,RPS17,UBE2H,CCT8,KRAS,EPHA4,PFDN1,RERE,HNRNPDL,TUBA1A,TUBB4B,SMARCB1,IL3,S100A8,HNRNPL,C1QTNF1,RAB1B,NOB1,TCP1,CCT7,LANCL1,MDFI,DIRAS2,PFDN5,RPL6,PPIB,TOR4A,ARL14EP,IKBKB,CRTAP,SLC39A13,BMPR1A,XRCC5,HSPA8,DDX5,PCGF2,EP300,UBE2D3,TRA2B,ADRB2,PHB2,PSMB3,FBXO42,APOBEC3A,RALYL,MAP2K1,RASL10A,PAPSS2,VEGFA,TAGLN2,CBX5,IREB2,PPP5C,APOBEC3B,MYC,HNRNPC,HNRNPAB,ATG101,CCT2,FBXW11,PIWIL4,GTPBP2 |
| 1.745e-10 | -22.47 | Ribosome, eukaryotes | KEGG pathways | hsa_M00177 | 91 | 61 | 7161 | 2463 |
RPS12,RPL27,RPL24,RPS28,RPS11,RPL22,RPL15,RPL39,RSL24D1,FAU,RPL32,RPS26,RPL7A,RPL7,RPS23,RPL8,RPS14,RPLP1,RPS16,RPL12,RPL4,RPS3,RPL13A,RPL28,RPLP0,UBA52,RPSA,RPS27L,RPS27A,RPL19,RPS9,RPL31,RPS4X,RPL10A,RPL3,RPS17,RPL17,RPS13,RPL37A,RPL23A,RPS2,RPL10,RPL27A,RPL9,RPLP2,RPL18,RPS7,RPS5,RPL23,RPL35,RPS20,RPS10,RPL35A,RPL10L,RPL29,RPS24,RPL6,RPS29,RPL26L1,RPL26,RPS15 |
| 1.745e-10 | -22.47 | Ribosome, eukaryotes | KEGG pathways | M00177 | 91 | 61 | 7161 | 2463 |
RPS5,RPS7,RPL18,RPLP2,RPL9,RPS15,RPL26,RPL26L1,RPS24,RPL6,RPS29,RPL29,RPL10L,RPL35A,RPS10,RPS20,RPL35,RPL23,RPS4X,RPL31,RPS9,RPL19,RPL27A,RPL10,RPL23A,RPS2,RPL37A,RPL17,RPS17,RPS13,RPL10A,RPL3,RPL28,RPLP0,RPL13A,RPS3,RPL4,RPL12,RPS14,RPS16,RPLP1,RPL8,RPS23,RPL7,RPS27A,RPS27L,UBA52,RPSA,RPL15,RPL22,RPS11,RPS28,RPL24,RPL27,RPS12,RPL7A,RPS26,RPL32,FAU,RSL24D1,RPL39 |
| 1.745e-10 | -22.47 | ECPAS (Ecm29 proteasome adaptor and scaffold) | protein interactions | 23392 | 313 | 140 | 19454 | 5460 |
ATP1A1,NRP1,CDKN2AIP,SYP,FBXO44,AR,PSMB2,GNAI2,VIRMA,EIF4H,ADRM1,RTRAF,MOB4,PSMC5,SLC1A1,CCNF,CHRM4,PSMA6,TMOD1,DCTN4,RPA2,HCST,KDELR2,CDC42,PSMC4,EIF4E,BCL6,KDM1A,VIPR1,RAB9A,RPA3,BAP1,SLC39A9,SIRT7,TSNAX,SLC2A1,ARL2BP,SMCHD1,PSMD7,DPP4,CALR,TMEM199,PCYT1B,EDEM1,PTP4A3,DUOXA2,ARF6,PSMB1,FA2H,TIMM8B,HRAS,UBE2G2,RAD23B,PSMC3,TFRC,EEF1A1,PSMB9,MGARP,SEM1,DYNC1I1,PSMA5,FARSA,TOLLIP,TGFBR2,RPS26,BRCA1,PSMD14,PSMD1,TMED4,CUL3,PSMA4,OPRM1,GPR17,LDHB,APLNR,RABIF,PSMD4,FBXO22,TUBB,PSMD6,PHF21A,S100A6,LMBR1L,RAN,PSMB7,NPY2R,EDEM3,AGTRAP,PSMB3,PSMC1,UFL1,NPTN,EYA3,CMTM6,STAU1,RP2,ADRB2,HSPA8,TXNL1,EP300,SPECC1L,POU5F1,HNRNPD,DDX1,HSPB1,KDM2A,PPM1B,AGR2,P2RY10,XPO1,HNRNPA1,DDRGK1,PSMD3,MARCHF5,VPS26A,DIRAS3,EGLN3,DNAJB9,HNRNPL,SPTAN1,AGK,SNX2,THOC2,PSMB5,CYB5B,RPS23,PLD3,TUBB4B,AQP3,TUBA1A,CKS1B,B3GNT2,PSMD12,FLOT1,PSMA2,PSMA1,DNAJB4,MYO1B,RPS24,RTCB |
| 1.784e-10 | -22.45 | RBM45 (RNA binding motif protein 45) | protein interactions | 129831 | 207 | 101 | 19454 | 5460 |
CUL3,HNRNPAB,HNRNPC,MCM3,BRCA1,RPS5,SNRPD2,SNRPD1,TUBB,ACTB,MATR3,ESR2,ERH,PABPC5,DDX39B,DDX5,PHB2,HNRNPA0,FXR2,MRPS35,DKK1,HNRNPA1,PPM1B,HNRNPD,RPL8,RPLP1,RPLP2,XPO5,CCAR2,SNRPD3,PAIP1,RPS10,HNRNPL,HSP90AB1,DHX15,RAF1,TNPO2,EEF2,RPS7,DNAJC25,POLR2D,PABPC1,HNRNPA2B1,HSPD1,SLC25A5,SRSF7,EWSR1,NUP42,HNRNPF,RBBP7,G3BP1,HNRNPDL,RPS4X,NONO,NTAQ1,CDKN2AIP,IGF2BP1,ELAVL2,EIF4A3,TUBA1B,TMEM176B,RPS3,RPS20,TRAF1,MIR34B,RPS14,RBMS2,RPA2,RPLP0,HNRNPH3,MIR205,PPM1G,H2BC12,SQSTM1,HMGB1,GTF2I,MIR29A,H2AC4,KPNA1,SSBP1,SYNCRIP,MIR25,PRR3,POLR2I,MIF,CAND1,RPS16,CDC5L,RBM42,EEF1A1,NFE2L2,CDK8,ILF2,MIR200A,DHX9,ZC3H11A,CSE1L,HNRNPK,THRAP3,CTNNBL1,RPS13 |
| 1.802e-10 | -22.44 | SLC2A1 (solute carrier family 2 member 1) | protein interactions | 6513 | 231 | 110 | 19454 | 5460 |
CSE1L,TOLLIP,EMC2,SURF4,DDX39A,CCDC47,TP53,CAND1,ARF6,RAC2,ACSL4,STT3A,TTL,SLC2A1,TMEM70,LAMP3,GAPDH,DPP4,EI24,CALR,USP2,TMEM209,SLC7A1,SLC25A51,HSPB2,SYVN1,PRKCB,RNF113A,RAB9A,RPA3,RHOU,RAB29,TTI2,MTRES1,RPA2,SAMM50,WWP1,STOM,STX17,GPR35,KDELR2,CDC42,COQ8B,TIMMDC1,SUMO1,MGST3,CCR2,RHOJ,SLC25A4,UBE2I,SFXN2,CHCHD6,VAMP3,CCNF,XPOT,UBE2H,TXNIP,DNAJC5,RAB2A,CIAO1,RAB18,KRAS,HECTD3,TRIM21,PLSCR1,RND3,RHOBTB1,EZH2,KDELR1,SOX2,NCSTN,TOP3B,EGLN3,HSP90AB1,RHOH,AGK,RAB35,MPDU1,PEX3,RHOG,XPO1,LAMP2,SYNJ2BP,PDIA3,RAB5C,COIL,STAU1,HSPA8,EXD2,SIGMAR1,YIPF5,RND2,TOMM22,BET1,MTX2,JAK2,MAD2L2,ESR2,PARL,ATP6AP2,FIS1,ILK,ATP1A3,LAMTOR1,RHOB,MYO6,BTF3,MYC,CUL3,RAB11A |
| 1.837e-10 | -22.42 | PGRMC2 (progesterone receptor membrane component 2) | protein interactions | 10424 | 269 | 124 | 19454 | 5460 |
RAB3B,TF,FKBP8,SLC6A8,SFXN1,RUSF1,ART5,SLC6A3,IGF1R,LPAR2,TFRC,RNF8,MTCH2,COMTD1,CCDC47,LBR,DNAJC1,ANKRD46,ARF6,LMAN1,TMPO,PTPN1,COQ8A,RAC2,COX20,FA2H,HSD17B11,ESYT1,POR,STYK1,ADIPOR2,SLC25A46,TMEM19,DPP4,EI24,LAMP3,TMEM107,ORMDL1,RAB29,GID8,RPA3,CYP2C18,DERL1,RAB9A,SSR1,GHITM,FGFR1,LMNA,RPA2,ACACA,CFTR,ST7,CDK7,CDC42,VIRMA,SEC63,TECR,OPTN,SMPD2,RAB2A,TMEM60,KRAS,HS2ST1,TMT1A,CYP2C9,COX8A,RAB4A,PTRH2,STIM1,RPN1,SERPINA5,OTULIN,CYB5B,RAF1,DNAJC25,ISG15,COX14,WIF1,NUP35,RAB35,MFSD5,GJA1,RHOG,FXYD6,ARMC8,HAX1,SLC39A13,PMP22,TMEM208,MARCHF5,RAB5C,LAMP2,ATG9A,FAM241A,RER1,HSCB,UFL1,PXMP2,STX7,AKAP1,RAB5A,RMND5B,PGRMC1,CLDN4,TOMM22,DUSP22,OTULINL,RND2,SEC62,ESR2,CYB5R3,LMBR1L,SEC61B,RMDN3,LMNB1,SPCS3,FAXDC2,VMP1,NTRK3,SLC38A1,CYB561D2,PRMT6,RAB11A,VEZT |
| 1.876e-10 | -22.40 | endoplasmic reticulum membrane | cellular component | GO:0005789 | 1204 | 448 | 19108 | 5553 |
PGAP3,INSIG2,SSR1,RNF139,CARD19,CYP4V2,ARCN1,XXYLT1,TSPO2,SLC30A7,GOSR2,RNF5,PLP2,SFTPA1,ANXA7,CYP1A1,GRIA2,CLSTN3,NCSTN,NFE2L1,NOS1AP,UBAC2,RNF103,GRIA1,FAXDC2,TMED4,CYB5R4,OS9,ALG2,CYP3A5,PSEN1,WDR83OS,ZDHHC16,FAF2,FLRT2,RETREG1,GABARAPL2,SPTSSB,TMEM33,GALNT1,STIM1,ESYT1,STX18,CYP2D6,TRAM1,ALG11,TAPBP,AGTRAP,LBR,HSP90B1,NSG1,SEC61A1,TOR1AIP2,CAMK2G,TEX264,CYP1B1,ELOVL7,RAB18,SPCS1,BOK,VTI1B,ACER3,FDFT1,CYB5R3,LRAT,RNF121,PTGDS,SEC22C,RDH11,RPL27,PCYT1B,CLN8,BSCL2,FA2H,ABHD4,TAPT1,DERL1,SEC61G,TRAM2,GDPD3,KPNA2,BCAP29,SELENOK,JKAMP,CYP2C8,RPN1,PDIA3,EVA1A,PIGA,PROS1,SEC22B,CYP17A1,MX1,PTPN1,HSD17B3,FKBP8,EMC10,CYP21A2,FATE1,TRAF2,KDELR1,MYRF,IFI6,PTDSS1,FAM8A1,RPS26,RAB6A,CIDEB,CYP2F1,DERL2,MYORG,ERO1A,SEC11A,RSAD2,CYP4F22,SDCBP,SHISA2,PIGW,SLC35B4,GALNT2,EMC6,STT3A,VAPB,REEP4,FKBP2,HACD1,ERG28,DHRS7B,IFI27,HSPA5,SRD5A3,EMC1,ZDHHC4,SRXN1,RTCB,UBA52,CHRM3,STX5,CYP26A1,SEC22A,MINAR2,CD59,KDSR,SLC35A2,RB1CC1,WASL,PNPLA8,TMCC1,RETREG3,TMEM97,AHCYL1,ORMDL3,NSDHL,FOLR1,CYP3A43,VMP1,SERINC1,SRPRB,PREB,TRAM1L1,GORASP2,FMO2,TMX4,REEP6,USE1,ELOVL3,SRI,SCFD1,RP9,LRRC8D,HACD2,SLC51A,SLC35B3,MOXD1,MSMO1,RDH10,CYP39A1,CYP4F12,GJA1,EXT1,TLR7,DNAJC25,CCDC47,DHRS3,STBD1,SPCS2,RNF133,FLRT3,PSEN2,TLCD3B,PML,ILVBL,TMEM38B,TMEM39A,ELOVL4,GGCX,TMEM147,RDH12,MACO1,LMBRD1,OSBP,CYB561D2,SPCS3,MRLN,IZUMO1,UFD1,RAB1B,UBIAD1,PLAAT3,VAMP7,SEC63,EMC4,SSR2,FITM1,LRRC8B,CYP2C9,DRD1,ELOVL6,ARL6IP5,C2CD2L,FITM2,EMC2,BECN1,RHOG,VKORC1L1,ATL1,TMED5,OST4,DEGS1,HSD11B1,RPS27A,MBLAC2,PLPP6,TEX261,DAD1,ZDHHC14,DIPK1A,RHEB,TUSC3,EMC8,RCE1,IL15RA,ABHD12,FADS2,UBB,RAB2A,TESPA1,FMO3,ZFAND2B,REEP3,TMED3,DNAJC1,HACD3,EPHX1,TMED1,TMED9,YIF1A,BET1,PYURF,TMEM208,CDC42,RETSAT,TMEM199,ORMDL1,MGST3,MTDH,SRPRA,KCNA2,PLN,JAGN1,CAV1,SCD5,TMBIM6,CAMLG,PIGK,RPS29,CDK1,DNAJB2,DLG1,SVIP,LMAN1,FKBP1A,KDELR2,TLR8,FZD6,CYP2R1,TMCC2,PSENEN,CYB5B,ALOX5AP,CREB3L4,GJC1,CYP2C18,SIGMAR1,PIGY,TMEM50B,CH25H,FKBP1B,CYP4F8,DUOXA2,UFL1,YIPF5,G6PC3,PITPNB,RNF26,SYVN1,RIC3,SLC37A4,EIF5A2,SAR1B,CALU,MARCHF5,TMEM203,B2M,PIGC,SEC61B,ATG101,EI24,JPH4,LPCAT3,SPTSSA,DNAJB9,CD4,TRIQK,ERLIN2,HACD4,MEST,SLC39A7,GABBR1,TMEM14A,DMPK,HMOX2,COPE,TMX3,AGPAT5,SURF4,BFAR,GNAI3,ERLIN1,STARD3NL,CNIH4,CYBC1,SEC62,BAX,UGT1A1,TMED7,TMT1B,CYB5R1,SFTPD,TAB1,SACM1L,MIA2,CREB3,TAPBPL,SELENOI,PIK3R1,ABCB9,RTN4,SFTPC,TMX2,CYP7A1,EMC9,CDIPT,DDRGK1,MGST2,FMO1,AQP11,APOO,LRRC8C,KRAS,NOTCH2,SDR16C5,OTULINL,TECR,SELENOT,POR,CALR,SLC35D1,TMEM174,SELENON,CFTR,PDIA6,CYB5A,EDEM1,SLC30A5,CD1D,FAF1,ATP6AP2,TMEM170A,PGRMC1,AGPAT1,ATG9A,CERS6,HTRA2,SC5D,SGMS2,RINT1,RAB9A,SEC61A2,POMT2,PEDS1,CNIH1,TM4SF20,MOSPD1,TLR9,RETREG2,DHRS4,HM13,GPR37,SPPL3,APH1A,ACSL4,CERS2,DPM2,PSKH1,SSR3,DHRS7,RAC2,NUS1,XBP1,DOLK,SLC39A13,SEC23A,SGMS1,ZMPSTE24,DIO1,STX17,PLD3,COPZ2,OSBPL8,DPAGT1,HRAS,ELOVL1,SELENOS,SEC13,PTPN5,PTGES,TMEM106C,GJB1,RPS28,EXTL2,LMBR1L,GPAA1,CASP4,PGAP2,TLR3,MPDU1,ALG5 |
| 1.887e-10 | -22.39 | ATP5PF (ATP synthase peripheral stalk subunit F6) | protein interactions | 522 | 194 | 96 | 19454 | 5460 |
RETREG2,BANF1,GFM1,CERS2,TOMM20,HSPA5,CRYZ,PLP2,GOLGA5,HEXIM1,MTRES1,INPP5K,UQCRC2,SCAMP2,ENO1,PTPMT1,MGST3,RALA,TFEB,VIRMA,CDC16,ATP5F1A,TUFM,ATP1B3,ATP5MC1,REEP6,ATP2B4,SFXN1,FASTKD5,SFT2D2,RDH11,LPCAT3,ATP5PB,MRPL11,METTL15,ZMYM3,SURF4,SLC35F1,NDUFS3,GFM2,COQ8A,SSBP1,AIFM1,RB1,STARD3NL,DERL2,ATP5PD,MSMO1,DPP4,EI24,ATP5MG,COX5A,TMEM70,BRD3,EXD2,ATP5F1E,ATP5IF1,SLC35F2,HSCB,CERS6,TOMM22,SLC19A2,PRDX3,YIPF5,ATP5PO,CAV2,TACO1,CCDC90B,MTG1,RETREG3,ATP5F1B,AUH,KDSR,MTG2,ACO2,PMPCA,FIS1,PHOSPHO2,SLC38A1,TMEM87A,HSPD1,NDUFA4,OPA3,HINT2,CHCHD2,VDAC1,ATP5F1D,MIEF1,PDHA1,PTRH2,FABP5,GATD3,PEX13,MTRF1,GSTO1,MRPS26 |
| 1.890e-10 | -22.39 | SF3B3 (splicing factor 3b subunit 3) | protein interactions | 23450 | 523 | 213 | 19454 | 5460 |
MIR34B,NEK2,HPS6,WRAP53,RPA2,UBE2M,MIR21,HEXIM1,SUPT7L,MIR7-1,BAP1,DDX46,MIR10B,NLE1,MIR107,MIR29A,SUGP1,TRIM32,RC3H2,UBE2H,SF3B6,TRAF7,MACROH2A1,KCTD9,TP53,DDX42,RNF8,MIR200A,SNIP1,MIR9-3,CDC40,HNRNPK,MIRLET7C,MEPCE,MIR16-2,H2BC14,ENY2,USP2,RBM17,CD81,COPS5,TAF9,NOL12,SMG8,TMOD2,SYNCRIP,FZR1,CAND1,MIRLET7G,TMPO,MBD5,MIR429,CDC5L,PIH1D1,SNRPA,DDX39B,HDAC5,SF3B1,HSPA8,DDX5,EP300,SRSF2,UFL1,STAU1,SSR3,APOBEC3B,MYC,EPS8,TTC33,SNRPB,LAMTOR1,CCT2,OSGEP,CMTR1,SCNM1,MIRLET7B,SMU1,SF3B4,ANAPC2,SSH3,ISG15,TUBA1A,NUDCD3,MIR222,SMNDC1,SMARCB1,HGS,TAF10,MIR9-2,EWSR1,MIR206,KRAS,MIR155,CCAR1,LAMP2,IFI16,MIR143,WWP2,YWHAG,MIR29C,DDRGK1,MIR31,AGR2,MIR221,MIR140,MAGOH,HSPB1,SRSF1,RBM5,EED,MIR214,SNRPA1,SNRPD3,MIR9-1,RBFOX2,SF3A1,MIR1-2,LMNA,METTL14,STOM,RPA3,PRPF4,MIR205,FLCN,MIRLET7I,TCEA1,MIR34C,SGF29,MIR7-3,FBXW7,TAF5L,FBXO7,RUNX1,AR,DNAJC8,TADA3,MIR145,TADA1,MIR16-1,CCNF,EIF4A3,GSK3A,COPE,NDN,YES1,CEP97,SMAD5,VIRMA,MIR15A,CD2BP2,MIR200C,MIR20A,MIR17,PPP4C,KLF10,EMC2,LSM4,HUWE1,THRAP3,MIR34A,MIR106B,RCHY1,MIR25,TOP1,MDM2,ZBTB2,SUPT3H,PPARG,SKP1,MIR106A,CUL2,CUL3,PRPF31,MIR98,BRCA1,LMNB1,MIR363,HSP90AA1,RIT1,SNRPD1,SNRPD2,AP1G2,TUBB,MIRLET7D,SNRPB2,TPBG,TXNRD1,E2F4,LGR4,EZH2,SF3B5,SNRPE,NEK9,HSPD1,SRSF7,UBE3A,TRIM37,RAD21,TAF7,PRPF19,STOML2,MAP1S,TRA2A,SKIC8,MIR1-1,WDR6,PHB1,MIR7-2,MIR141,KRT8,CCAR2,SPTAN1,DHX15 |
| 1.916e-10 | -22.38 | PABPC4 (poly(A) binding protein cytoplasmic 4) | protein interactions | 8761 | 424 | 179 | 19454 | 5460 |
PPP1CC,RUNX1,MAPRE1,PAIP2,IVNS1ABP,RPS20,GSK3A,EIF2AK2,METAP2,CCNF,RPL13A,NDN,RPLP0,RARS1,MTDH,SQSTM1,SIRT7,RPA3,SOD1,AATF,BRIX1,RPL4,NF2,HDAC6,MOV10,DNAJC7,PTPN1,PRNP,TSC22D3,ARF6,DCUN1D1,RPL15,DDX39A,EEF1A1,APOBEC3D,YTHDF2,FBP1,SAP30L,SRP72,ILF2,RIGI,CUL3,CUL2,BRCA1,YWHAZ,RPS9,RNF208,RAN,PRRC2A,ACTB,EIF4A2,PRDX3,WDR77,H1-5,EMC9,LARP4B,RNF7,NUBP2,CRY1,G3BP2,YTHDF1,TRA2A,HNRNPA1,HNRNPD,RB1CC1,PPM1B,TSG101,IGBP1,PHB1,IFIT2,RPL8,DHX15,RPL7,ACTN4,RAF1,RPS11,CHMP4C,EZH2,ZC3H7A,HNRNPA2B1,GNL1,TRIM37,EMC8,G3BP1,MAT2A,UBE2H,IGF2BP1,ELAVL2,RC3H2,SPOP,PSPC1,RPS3,SRPK2,SRC,CFTR,CDC42,KLF4,HEXIM1,RPA2,RNF113A,LSM12,TRIM3,RPL27,BAP1,MARS1,HSPA5,TOMM20,EIF4E,EDC3,GAPDH,CSNK2A1,COPS5,ENY2,SNRNP70,H2AC4,PREP,ALYREF,SYNCRIP,TMPO,RPS16,CAND1,FZR1,DUSP1,TP53,TNRC6C,UBL4A,HBP1,DHX9,MEPCE,CSE1L,BAG3,RPL39,BTF3,HNRNPAB,MYC,H1-1,NSA2,FBXW11,SURF2,ESR2,DES,MATR3,ELK4,MED31,PIH1D1,NUFIP2,PPT1,AKAP1,EP300,DDX5,HSPA8,DDX39B,STAU1,UFL1,CTNNB1,DDRGK1,CPEB1,YWHAG,XPO1,RPL6,WWP2,IFI16,GSTM3,HSPB1,DRG1,YWHAB,SMAD9,FKBP4,FUBP3,PAIP1,HNRNPL,PAIP2B,SOX2,RPL18,GLE1,TRIM11,PABPC1,HNRNPDL,IMPA2 |
| 1.936e-10 | -22.37 | YES1 (YES proto-oncogene 1, Src family tyrosine kinase) | protein interactions | 7525 | 364 | 158 | 19454 | 5460 |
PAK2,DUSP22,PPP1CB,FUNDC1,RND2,CLDN4,STX7,CCDC186,RP2,CYFIP2,FXR2,TMEM185A,RAB5A,SF3B1,TRIM5,HSPA8,JAKMIP1,HSP90AA1,RHOB,CCT2,FAS,FYTTD1,LAMTOR1,SNRPB,BTF3,PIK3R3,RAB11A,HNRNPC,MYC,RPL10,DES,ESR2,JAK2,ERH,LAMTOR3,NFKBIA,DLG4,CRKL,SSBP3,RND3,CCR1,TMEM59,SOX2,FAF2,TRAF2,NCSTN,TOP3B,FASLG,FLOT1,CDK20,LASP1,KIT,G3BP1,KRAS,PSMA1,PICK1,HSPB1,CBL,CDKN1B,TRAF6,ZCCHC9,RHOG,GAS8,RAB5C,LAMP2,PIK3R1,MTRF1,NPC2,HSP90AB1,DHX15,DIRAS3,TCP1,RHOH,GJA1,CEP57L1,RAB35,CSNK1G3,HEXIM1,MET,SH3GLB2,STOM,FGFR1,CHMP1A,GPR35,CDK1,CD46,FTH1,CD2AP,GABRA1,CDC42,SNRPN,SPR,SF3A1,DDIT4L,ATG16L1,CERS2,RAB9A,RPA3,RHOU,LIN7C,DVL2,MAPRE1,NRP1,BICD2,NIF3L1,DNAJC5,SKAP2,AR,RAB2A,STK38L,SRC,RHOJ,YES1,GRPEL2,PTEN,SYNGR1,CTTN,GAB1,NUPR1,ILF2,NHERF1,TFCP2,THAP1,SOCS3,MAP1LC3B,CENPM,CTNND1,OLA1,SOCS2,TGFBR2,ERLEC1,CAMKV,CAMK2G,SNAP23,RAB27A,SLC25A11,GLUL,FGR,SHC1,BECN1,MED21,LAMP3,HDAC6,RBM17,LAMTOR2,FAM20C,CEP15,DPP4,CD36,CAV1,LMAN1,STX6,CDK9,ARF6,RAC2,ACBD7,AIP,HRAS |
| 1.942e-10 | -22.36 | RAB1B (RAB1B, member RAS oncogene family) | protein interactions | 81876 | 242 | 114 | 19454 | 5460 |
HNRNPL,OCRL,RAB11B,NDUFS8,PHB1,EED,TRAF6,AGR2,AHSA1,HNRNPD,RAB5C,LAMP2,ETFA,VDAC1,PSMA1,RAB8B,SSRP1,RAB18,RNF26,TMED7,HSPD1,SLC39A3,GDI2,RAB6B,BZW2,PDHA1,EZH2,RPN1,STX12,RAF1,B3GNT2,ESR2,RABIF,DLST,ARF1,SEC61B,ATP1A3,LAMTOR1,SCFD1,CUL3,LDHB,RUSC2,RAB11A,MYC,KDSR,BAG3,SLC30A5,TOMM40,UCHL3,STX7,RAB5A,EP300,AKAP1,PMAIP1,RABAC1,HSPA8,CAV2,CNDP2,TOMM22,ACTL6A,RAB6A,CNPY3,YIPF5,MIF,ARF6,TRAPPC2L,ATP1B1,LAMP3,HDAC6,TOMM40L,RAB1A,IGF1R,EMC2,RAB13,FURIN,DHRS7B,TRAPPC13,UBL4A,CCDC47,LDHA,RAB14,TECR,UQCRQ,VAMP3,OPTN,CCNF,UQCRC2,PTEN,CHRAC1,RAP2C,ATP1B3,IGF2BP1,ATP1A1,CDC73,RAB2A,GORASP2,HSPA5,TOMM20,RPA3,SLC39A9,BAP1,RAB9A,RAB33B,RTN4,GOLGA5,LSM2,RPA2,CYC1,HEXIM1,VPS54,UBE2M,FUT8,ATG16L1,CDC42 |
| 2.001e-10 | -22.33 | HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha) | protein interactions | 3030 | 491 | 202 | 19454 | 5460 |
CCDC90B,VDAC2,LMBR1L,ESR2,PSMD4,ATP5F1B,PCCB,ATG101,BTF3,MYC,ICAM1,EP300,HDAC5,STAU1,PHB2,NDUFS2,GPC4,BET1,PAFAH1B1,SYK,TOMM22,PIH1D1,SDC2,CORO1C,YBEY,GYS1,SDC4,HSP90AB1,COX14,RMND1,DDRGK1,WWP2,HSPB1,NDUFB8,POU5F1,AGR2,GNA11,CBLL1,VDAC1,EPHA4,EEF2,SOX2,DNAJC25,TUBA1A,MAX,TOP3B,PDHA1,TUBB4B,MACROH2A1,GNAO1,UQCRC2,SRC,UBE2H,ATP1A1,SPOP,RNF113A,GFM1,BAP1,HSPA5,TOMM20,SLC25A51,MRPL40,CYC1,HEXIM1,UBE2M,FGFR1,RPA2,COX4I1,CD274,SSBP1,MYL12A,TMPO,DNAJC1,CAND1,FZR1,COX5A,DPP4,TUBG1,MAP1B,MEPCE,TOLLIP,CAMKV,H3C1,METTL15,WBP11,MTCH2,TP53,KIF1C,KBTBD4,PREB,ATP5PB,NUPR1,FURIN,RELL2,CAPZA2,CDH8,TFCP2,CYB5R3,TUBB,ACTB,TOMM40,CUL3,PMPCA,RAB11A,MTG2,AUH,NTRK3,HSP90AA1,RHOB,CFDP1,EXD2,ATP5MK,CXCR4,GPC1,HSCB,PRDX3,SLC25A3,ADNP,MED23,ATP5PO,GATD3,COPS2,CETN3,MAP1LC3A,PHB1,OCIAD2,NDUFS8,EGLN3,STOML2,MTRF1,MED4,MRPS26,RHOG,COX8A,HINT2,NDUFA4,HSPD1,TRIP4,ETFA,GABARAPL1,CYB5R1,RAF1,B3GNT2,NGB,EZH2,MSN,PTEN,OPTN,CCNF,VIRMA,SH3BGRL,UQCRQ,MGST3,TUFM,ATP5F1A,DNAJC19,NRP1,CDC73,SQSTM1,SIRT7,PPM1G,RPA3,FBXW7,PDHB,FTH1,GABARAPL2,CDK7,UQCRC1,CCND1,MTRES1,MET,EPHX1,HSP90B1,COX6C,TES,RCHY1,AIFM1,ATP5PD,ATP1B1,HDAC6,ATP5MG,GRSF1,CALR,OSBPL8,HSD17B10,EMC2,IGF1R,GNG5,HAPSTR1,SFXN1,RAB1A,PRDX4,RIGI,VRK1,AURKAIP1,MAP1LC3B,MRPL11,FBP1,CASK,SLC25A20,AP1S2,NDUFS3 |
| 2.140e-10 | -22.27 | TENT5C (terminal nucleotidyltransferase 5C) | protein interactions | 54855 | 138 | 74 | 19454 | 5460 |
PSMB10,ETFA,PSMA2,PSMA1,G3BP1,RTCB,IDH1,PDIA6,HSD17B10,SEPTIN7,HNRNPA2B1,PSME1,NSDHL,EHD4,POLR2C,PLS3,PGM1,ACTN4,TPD52,CCAR2,CPNE1,COPS7B,MTAP,FAHD1,PBDC1,PHB1,PSMB4,PSME2,EEF1B2,HNRNPD,GSTO1,AK2,EIF3D,COPS5,PGAM1,STOML2,G3BP2,PSMC1,NSFL1C,PDHB,SQSTM1,PSMA3,PRDX6,TXNL1,HNRNPH2,PGK1,ANXA7,AKR1A1,FDFT1,OXSR1,HEXB,LAP3,PSMC4,ATP6V1C1,BCCIP,IDE,SUCLG2,PPAT,PRDX2,ACAT1,TRIM27,DLST,ENO1,CYB5R3,PSMA6,MAPRE1,MDH1,YWHAZ,GLOD4,EIF3G,AK3,GSTK1,LDHB,ACO2 |
| 2.155e-10 | -22.26 | PSMC1 (proteasome 26S subunit, ATPase 1) | protein interactions | 5700 | 339 | 149 | 19454 | 5460 |
ISG15,PPP2R1A,B3GNT2,POLR2C,MOB3C,RPN1,STMN2,EZH2,VPS33A,TRIM11,UBE3A,SKA1,PSMD12,RAD21,KRAS,PSMA1,PSMA2,RBBP7,DDRGK1,PSMD3,MARCHF5,DPY30,CBL,HSPB1,TRAF6,PSMD10,COPS2,WDR6,PSME2,PSMB5,PPP2CB,DUSP6,PSMB4,EGLN3,SRSF10,DIRAS3,DHX15,DYNC1I2,SUMO2,CCAR2,PPP1CB,PSMB3,PPARG,PSMB7,CRY1,HSPA8,TXNL1,PSMA3,DDI1,PSMC1,POLA2,CCND3,NSFL1C,MRPL57,STAU1,PSMD1,BTF3,CCDC85B,BAG3,MYC,ALDH1L1,PSMA4,CUL3,CDKN3,RIT1,LAMTOR1,PSMD14,BRCA1,RHOB,LMBR1L,DLST,PSMB6,PSMD4,PSMD6,TENT5C,PSMB9,TOPORS,PSMC3,RAD23B,TAF2,TMEM31,HAPSTR1,HSD17B10,MAP1B,FAF1,PSME1,RPS13,MRPL22,MEPCE,FBXO25,VTA1,FKBP8,PSMA5,CNOT7,HUWE1,SEM1,TGFBR2,HDAC6,SUV39H1,ATP6V1D,CCDC92,PSMD7,PTGER4,PSMB1,MDM2,CDC5L,FZR1,PRNP,UBLCP1,PAAF1,PSMC4,AKR7A2,SF3A1,UBA52,UBE2M,HEXIM1,ACACA,RPA2,METTL14,SNAI2,GRM2,SQSTM1,BAP1,RPA3,SOD1,EIF4E,HSPA5,ATG4C,KDM1A,SMC4,DESI1,FBXO7,AR,USP14,PSMB2,MORF4L1,ATP1A1,PDCD4,UBE2H,MRPS16,PSMC5,SNX12,UQCRC2,CCNF,PSMA6,VIRMA,MRPS21,CHMP5,ADRM1 |
| 2.157e-10 | -22.26 | positive regulation of protein metabolic process | biological process | GO:0051247 | 1247 | 467 | 18204 | 5365 |
KIT,ANP32B,FAS,MIR206,ODAM,TOLLIP,MSN,CRKL,CARTPT,UBE2N,DIRAS2,UBE2D1,PSMC3,SKP1,PAK2,ATP5IF1,MIR221,TGFBR2,IL2,ARRDC3,CCND1,NRP1,PCSK9,FGF1,NR1H2,PTEN,JAK2,BCL2L1,RGMA,DERL1,BAD,EGLN2,CRY1,GSK3A,DVL2,CDK5RAP3,IL1B,AKT1,AIFM1,TNFSF15,NOP53,UBE2V2,FAM107A,WNT7A,UBE2V1,ITGA2,TANK,RPL26,KHDC1,TLR6,SLCO3A1,GABARAP,RNF128,IFNA13,RPS4X,BOK,PACSIN3,PIK3R3,EIF3D,PDCD10,NFKBIA,APH1A,IGF1,CYFIP2,CCND3,MT3,TXN,BAK1,CTSK,CTNNB1,GH1,TNFAIP3,RGCC,CREBL2,MCL1,SYNCRIP,PPP2R5A,HDAC3,EMP2,SMURF1,PLCB1,TLR9,ATG7,IFNK,NOS1AP,TNFRSF1B,MOB3C,RPS2,DNAJC3,MIR30B,IFNA2,MIR21,DNAJB2,TNIK,UBE2S,EHD4,LCP2,LILRA2,NMI,BCL2A1,CLEC6A,RIGI,MAD2L2,SMYD3,PRKAG1,RMND1,CD80,CD36,PMAIP1,UCN,LDLR,ENO1,AURKAIP1,HSPD1,UHMK1,PPP1R12A,TRAF7,VEGFC,PELI1,IFNGR1,FLOT1,CLIP3,HAX1,PRNP,IL12B,UBE3A,MMP14,UBE2K,ACVR1C,MAGEC2,UBB,CD86,MMP9,PAIP1,IFNA10,MOB3B,IL6,TOM1L1,ERP29,BAX,CYP1B1,MYLIP,RARRES2,TRAF6,FXR2,VIP,TRIB1,TBK1,XRCC5,CCL19,FAM161A,DIRAS1,PIAS1,ARL2BP,PML,HCLS1,PHF23,DISC1,CHI3L1,PSMC5,SEMG2,MAP2K6,IGF2BP1,PABPC1,MIR16-1,WBP1L,CRADD,PIH1D1,TESK1,DCUN1D3,CD40,BOLL,RALB,NLRP1,CLU,SYK,FGF16,PSMC1,MIR205,STK11,S100A8,PRR5L,HDAC6,FBXW7,NKX3-1,SMAD3,VSIR,DCUN1D5,BIRC2,TFRC,YES1,LACRT,EGLN3,PSMC4,RAP1A,EIF4A3,TRIM32,HNRNPD,UBE2L3,RHBDD3,OSM,BRMS1,CUL3,NBN,CAMK1,METTL14,EIF2B5,NTRK2,NTRK3,IFI16,MTPN,PRELID1,FGF23,EIF3E,NFE2L2,TICAM1,IL15,MPV17L2,NSMCE3,SEMA7A,VEGFA,IL23A,SUMO2,ANGPT1,UQCC2,ASB11,SRC,CSH1,RB1CC1,IL18,FAM162A,TNFSF12,POLR2G,RNF41,FASLG,LEP,SQSTM1,PIK3CG,PHB2,TAB2,TCIM,NTF4,IFNG,DTL,IL17F,STX5,MIR15A,CAMP,OAZ3,CACUL1,SOX9,NDFIP1,RGN,CCL21,CIRBP,CSNK2A1,PAEP,DLG3,HSPE1,PYM1,PICALM,FIS1,TOPORS,KDM1A,MMD,IL5,SUMO1,FCGR1A,MAP2K1,DYRK1A,RAB1B,DHX9,PXYLP1,PTPN22,GCLC,USP13,RAP2B,ADRB2,GREM1,ADTRP,TNFSF18,PROX1,SNX33,PIWIL2,CCR7,OSBP,MAP2K3,CHP1,TGFB2,ZFAND2A,SVIP,KRAS,NCK1,SEC22B,FGF10,NPTN,IL4,IFT57,HSPA5,SOCS5,HTRA2,PSEN1,ARL6IP5,CD81,RPS27L,CD4,HBEGF,IDE,FURIN,USP8,MAVS,TAB1,IFNB1,CAV1,EFNA5,USP5,CAV3,HSP90AB1,AGAP2,RAB1A,CD28,VGLL4,RWDD3,EIF5A2,TPD52L1,HTR2A,BCL10,IL12A,MIF,PSRC1,PDCD5,MAP3K12,HSP90AA1,CSF2,SOCS4,IL6ST,EPHA4,TLR3,CCL5,SPON1,EFNA3,NUPR1,DUSP19,LRRTM3,FZR1,PPIA,DAPK1,CDC20,IER3,MYC,RCHY1,ZER1,CSNK1E,FERMT2,ACVR1,PSME1,LDB1,NLRP3,MIR17,CTSD,F2,POMT2,CLDN3,CDKN1A,USP16,NDN,DCUN1D1,PSMD10,TNFRSF14,ADNP,NLRP2,STRADB,DAP,FBXW11,ILK,SH3BGRL,VPS28,CLDN4,STUB1,YTHDF1,FGF7,HMGB1,AGER,PYCARD,HRAS,OAZ2,CAB39,S100A10,LARP4B,ROCK2,MUL1,CX3CL1,RAF1,NGRN,POLDIP3,TNF,ADIPOQ,FGF17,FGF3,DDRGK1,MAP3K11,PHB1,TRIM6,EEF2,RPS3,TRAF2,CX3CR1,FAXDC2,GPNMB,CDKN1B,COP1,RAP2A,PLGRKT,HECTD1,SGTA,PSME2,CSNK1A1,CCDC22,PPARG,RBM3,SP1,EGR1,IL34,RBCK1,TGFB1I1,EPO,DET1,RNF139,CHRNA7,IL3,UPF3B,EZH2,NCSTN,FBXO22,YTHDF2,FAF1,RAP2C,HSPA8,FGF22,PTPN1,GHR,BAG2,ADORA1,MIR26B,PSENEN,P2RY1,FGFR1,TLR4,APLNR,DLG4,HUWE1,PTPN11,KLF4,TP53,SPPL3,CTSC,STK4,TNFSF10,MDM2,DIPK2A,CCNY,OAZ1,IL13,LEPR,MIR34A,IL21,CLEC7A |
| 2.169e-10 | -22.25 | mitochondrion organization | biological process | GO:0007005 | 434 | 189 | 18204 | 5365 |
GHITM,NECTIN2,COX14,SQSTM1,IFI6,TOMM70,PHB2,TMEM14A,SLC25A46,UQCC2,NDUFAB1,NDUFAF6,NDUFB10,RB1CC1,SOD2,CNP,USP30,MEF2A,COX10,NDUFS2,NDUFAF3,COX20,BCS1L,TP53,BLOC1S2,NDUFB8,FUNDC2,NDUFAF4,TIMM21,LIPA,COX16,PET117,TOMM7,RETREG1,SESN2,COA5,APOO,LYRM2,GABARAPL2,MTX2,AGK,BNIP3L,PPM1K,MIR29A,RAB32,ADCK1,GABARAPL1,TOMM6,COA1,CHCHD4,SDHAF4,MAIP1,FANCG,RRM1,COX17,HIGD2A,CLN8,TRAK2,NDUFB4,SAMM50,FBXO7,CCAR2,POLDIP2,NDUFA5,COX19,CLU,CNTNAP1,TIMM13,PHB1,SLC25A4,ARMCX3,NDUFAF2,MUL1,ATG4A,IFIT2,ATPAF2,NAIF1,ARMC1,NPTX1,TMEM126A,FEZ1,PPIF,RIMOC1,TRMT10B,VPS54,TACO1,COA4,MIR17,TIMM8B,SLC25A5,SDHAF1,ATP5F1D,NDUFB5,TERT,TAFAZZIN,ATG3,TOMM20,CHCHD2,MTCH2,WDR45,UQCC6,NDUFA12,HAX1,HSP90AA1,NDUFB7,AKT3,MPV17,HSPD1,MAP1LC3B,SSBP1,PPP2CB,NDUFS8,CHCHD6,ACAA2,MIEF1,PRDX3,BAX,NDUFB6,TOMM40,GGCT,IER3,IMMP2L,STOML2,ATG9A,MTM1,COX7A1,FXN,SFN,SELENON,MCL1,NDUFC2,MFN1,HTRA2,ATG7,FMC1,NDUFS3,PMAIP1,GABPB1,PIM2,TMEM70,MGME1,BCL2A1,EDNRA,TIMM29,THG1L,NOA1,TMEM11,FUNDC1,SDHAF2,SLC25A31,GABARAP,TIMM10,AKT1,AIFM1,GCLC,NDUFA1,TOMM22,FBXL4,TWNK,RAB29,CTSK,BAK1,PYROXD2,BOK,HSD17B10,ROMO1,CIBAR1,UCP2,UQCC3,VDAC2,NDUFA2,CHCHD3,RAB3A,ATG4C,SLC35F6,HIGD1C,BECN1,ATP5IF1,FIS1,PID1,TIMM8A,TMEM126B,BAD,PARL,MAP1LC3A,GSK3A,CAV2,BCL2L1,MIR29C |
| 2.186e-10 | -22.24 | CISD1 (CDGSH iron sulfur domain 1) | protein interactions | 55847 | 83 | 51 | 19454 | 5460 |
ATP6V1C1,CDC42,RND2,RPA2,EXD2,SNRPA,RPA3,MAVS,AKAP1,HSCB,STX7,TOMM20,PXMP2,RAB11A,TOMM40,FIS1,CCNF,OPTN,VDAC2,PTPMT1,RMDN3,WDR45,VIRMA,TECR,MTCH2,NDUFA2,MGARP,TOMM7,NDUFA12,STX12,NDUFA4,ABCE1,VDAC1,KRAS,CHCHD2,IMMP2L,FKBP8,PDE2A,SLC25A46,RPL6,TSPO,PPIB,PSMD7,RHOG,COX4I1,SDHB,AIFM1,RAC2,FZR1,EGLN3,ATP5PD |
| 2.187e-10 | -22.24 | SMC5 (structural maintenance of chromosomes 5) | protein interactions | 23137 | 976 | 362 | 19454 | 5460 |
HMGA1,ZNF207,HNRNPA1,PDAP1,HNRNPD,BRD9,DHX15,PPIA,SRSF10,CKS1B,JUN,NME1,NDUFS6,RPN1,SART3,HNRNPA2B1,HSPD1,SLC25A5,SRSF7,FAM76B,COPS4,SSRP1,RAD21,RPS27A,RPS29,ATF1,SMARCE1,PRPF31,BRCA1,YWHAZ,HSP90AA1,RPS5,ZNF174,VPS72,SEC61B,ZMAT2,SNRPD2,TUBB,ACTB,PRRC2A,ERH,RFXANK,SLC25A3,MFAP1,NOP53,YTHDF1,CYFIP2,NME2,EIF5A2,KRR1,RPL12,MYBL2,THOC1,CWC15,NKRF,PQBP1,NSMCE3,VRK1,SMN1,PTGES3,RACGAP1,DNAJC8,CDC73,ENO1,CTTN,TUBA1B,RPS12,DEK,SCML2,UBA52,SF3A1,TXNL4A,UQCRC1,PICALM,HNRNPH3,HELLS,TCEA1,BAZ1B,DDX50,NDUFV2,DDX1,PRCC,CD63,FUBP3,SUMO2,SNRPA1,SNRPD3,HNRNPL,RPS10,HSP90AB1,EEF2,RPS7,H2BC1,DLX1,TUBB4B,CSTPP1,FAM168A,EWSR1,RUVBL1,HNRNPF,CBLL1,RPS4X,CCAR1,HNRNPAB,HNRNPC,LDHB,COX6B1,SNRPB,H2AZ2,CKB,RCL1,H1-1,MIDEAS,VDAC2,ZMYM2,ZCCHC7,MATR3,APEX1,CBX5,ZC3H14,EIF4B,NUFIP2,RPS28,DDX39B,DDX5,SF3B1,EEF1G,PHB2,SRSF2,COX5A,API5,GAPDH,PPIL4,SMCHD1,MAP4,TAF9,ALYREF,METAP1,RPS27L,MYL12A,RPSA,TP53,STRBP,DISC1,DDX42,RP9,CBX3,MAP1B,DHX9,HNRNPK,H3C1,RPL17,SUGP1,SMARCA5,CFL2,CFL1,STN1,MECP2,CDKN2AIP,RBM7,IGF2BP1,TMA7,UQCRC2,PSPC1,MACROH2A1,CSNK2B,CD2AP,HBB,LEMD3,LUC7L3,CYC1,TFIP11,NBN,PML,RPL27,DDX46,WDR3,PRDX1,PRPF19,RPL23,RSBN1L,PHB1,THOC2,HP1BP3,CYB5A,BUD31,NOP58,NDUFS8,FEN1,GTF2E2,NUP153,SF3B5,ARGLU1,RBBP7,EMC8,G3BP1,RFC3,SRSF4,NOP16,MCM4,RBM15B,MCM3,LMNB1,RAN,RBBP4,DYNLL1,CHCHD3,MTX2,H1-5,ADNP,ATP5PO,MYL6,RTF2,THOC3,NUP50,CCDC86,ATP5IF1,COIL,SNAP91,MPHOSPH10,TOPBP1,HACD3,SRP14,H2AZ1,PWP2,TOP1,POLR2I,ATP5PD,YTHDF2,LBR,EEF1A1,ING1,MLLT6,SRP72,ILF2,HSD17B10,PC,SEPTIN7,ZC3H11A,THRAP3,MDC1,SNRPG,NDUFB10,PPP1CC,NONO,ATP5F1A,TADA3,EIF4A3,PELP1,RPS20,TRIM24,ACAT1,RTRAF,SLC25A4,KLK9,LDHA,RPL22,EEF1E1,SNRPN,MYL12B,SAP30BP,RPS14,RBMS2,EDF1,LMNA,JUP,TOX4,IFRD1,NOL7,RPLP0,PRPF4,MTDH,H2BC12,HMGB1,GTF2I,EIF5B,DGCR8,AATF,SS18,MBD3,PPIB,SRSF1,RFX5,TRIR,LYAR,FAM98A,MEAF6,HMG20A,UQCRH,CAAP1,PABPC1,RBM3,CCT8,TOP2B,RTCB,VDAC1,HMGN4,ZNF609,HNRNPDL,POLDIP3,RBM27,FTSJ3,H1-10,ZHX3,GTF2F2,SF3B4,FBXO22,ATP5F1B,NUP62,DHRS4,ZNF362,XRCC5,SLU7,RFC4,SNRPA,HSPA8,STAU1,HNRNPA0,RBM17,SNRNP70,RPL10A,CDK12,COX4I1,EEF1B2,SDHB,SYNCRIP,RPS16,SURF6,CDC5L,DKC1,TMPO,SRFBP1,ZMYM4,WBP11,IK,CHAMP1,TCEA2,NOSIP,H2BC14,SRSF12,SUB1,RPS17,H2BC9,CCDC174,ANAPC4,ZBTB33,UBN1,LIG3,RPS3,CREB1,SGTA,QSER1,EIF2S2,CSTF3,PPP1R10,SUMO1,NTPCR,ZNF326,RPA2,ACACA,HSPA5,ZC3H15 |
| 2.194e-10 | -22.24 | MRPL11 (mitochondrial ribosomal protein L11) | protein interactions | 65003 | 393 | 168 | 19454 | 5460 |
HEXIM1,PDCL,TFIP11,SAMM50,MRPS34,QRSL1,CFTR,RBMS2,KLF12,MRPL10,NDUFAB1,MPV17,MRPL20,POLDIP2,MRPL41,FBXW7,MRPL40,NME4,PDHB,MRPL17,MTDH,DLAT,GFM1,TWNK,UBE2H,RC3H2,MRPS16,TUFM,H2BC9,ANAPC15,PYCR2,NDUFAF2,RPL13A,JAKMIP2,PTEN,ACAT1,MRPS28,SRP54,CCNF,MRPL53,MRPL49,MRPL51,NDUFS3,TFCP2,THAP1,BCS1L,HADH,AURKAIP1,PPIF,MRPL47,NDUFA2,ATP5PB,FKBP8,MRPS18C,MRPL22,HSPE1,PDE12,CAMK2G,MRPS33,THG1L,MRPS18B,ATP5PF,SNIP1,MRPL52,SNRNP70,COPS5,COX5A,MOV10,DPP4,GRSF1,KLF9,ZBTB2,MRPL24,MRPS23,ATP5PD,DBT,MALSU1,MRPL50,CAND1,MGME1,ALYREF,MRPS9,SSBP1,NDUFA5,CRYAB,MRPS18A,ATP5PO,NDUFAF3,MRPL12,AGTRAP,TOMM22,RPL27A,CMAS,MRPS7,PHB2,UFL1,NDUFS2,TMEM177,HADHA,JAKMIP1,NGRN,RIT1,RPS5,MRPS25,NOA1,BTF3,MRPL16,CUL3,HNRNPAB,PYCR1,MYC,MTG2,ESR2,RPL10,RPL19,NDUFAF4,RPL35,TAX1BP1,ATP5F1B,MRPL23,MRPL13,PRMT5,MTG1,DLST,TACO1,PNMA1,NDUFA12,NDUFS6,ZNF526,PDHA1,NUDT19,PAIP2B,ELF1,SOX2,ETFB,E2F4,TOP3B,HNRNPDL,MRPS17,SRSF4,RPS27A,ATP5F1D,ZBTB14,ETFA,KGD4,MRPS11,HINT2,PREPL,TRIP4,LHX2,MRPS26,MRPL18,DDRGK1,MRPL9,NDUFV2,HNRNPA1,RPL6,CDC26,MRPS35,STOML2,HMGA1,CLPX,DDX50,COX14,NDUFS8,CCDC172,HNRNPL,PHB1 |
| 2.249e-10 | -22.22 | HMGB2 (high mobility group box 2) | protein interactions | 3148 | 229 | 109 | 19454 | 5460 |
CHN2,SSRP1,RPS4X,PSMD12,PABPC1,RPL31,CDK5,EZH2,RPS23,RPS7,SNAPIN,OCRL,RPS10,EIF2S1,PGR,CEP19,RPL8,RPLP2,RPLP1,EED,AGR2,POU5F1,RPL6,PDIA3,HMGA1,CTNNB1,YWHAG,PPIB,NOP53,COIL,RPS28,DDX39B,CCDC86,EP300,HSPA8,ARCN1,CSNK1A1,MYL6,NUFIP2,RPL27A,ZNF428,PRDX3,RPL35,APEX1,RPL10,PRRC2A,EIF3K,FAU,H1-10,RPS6KA4,CKB,RPS26,LDHB,MYC,CREBBP,GGH,RPL39,ZNF668,H3C1,EIF3E,RPL17,ABCE1,RPL23A,RPL3,CBX3,SRP72,TP53,RPSA,RPS27L,RPS16,RPL32,HACD3,CD274,RPL24,CRBN,TSNAX,RPL10A,RPS2,MOV10,GAPDH,MIEN1,RPL4,HMGB1,RPS15,RPL27,BAP1,SQSTM1,PRKCB,SAMM50,SSR1,CDK1,RAG1,HEXIM1,RPLP0,ZNF622,RPL22,BCCIP,ROCK1,RPS20,SRP54,CSNK2B,PKNOX1,LGALS8,GZMK,UBE2H,TBC1D25,AR,USP14,FBXO7 |
| 2.311e-10 | -22.19 | FKBP8 (FKBP prolyl isomerase 8) | protein interactions | 23770 | 524 | 213 | 19454 | 5460 |
RPA2,SSR1,USE1,SAMM50,LEMD3,CDC42,CFTR,SLC25A51,TOMM20,TEX264,RAB29,IRF3,PSEN2,TMEM254,RAB9A,DERL1,CISD1,MFSD14B,UBE2H,C9orf72,PSMB2,DNAJC5,ADRM1,UQCRC2,PSMA6,PSMC5,SRP54,PTPMT1,TMEM31,PSMC3,PREB,SNAP29,MTCH2,PSMA5,NUP107,RAB3B,FKBP8,MAP1B,STX18,CYBRD1,DNAJB2,ANKMY2,COPS5,DNAJC1,TMPO,LMAN1,STT3A,CAMLG,RAC2,TOMM22,PSMB3,SEC62,CNPY3,UFL1,EMC1,ADRB2,PHB2,JAGN1,EP300,AKAP1,SPCS3,PSMD14,FIS1,DNAJB6,OST4,PSMA4,PSMD1,PSMD4,PSMD6,FBXO22,ATP6AP2,ESR2,LMBR1L,VDAC2,RETREG3,ANAPC2,PTRH2,MOB3C,STBD1,DNAJC25,PSMA1,USP30,PSMA2,RUVBL1,VDAC1,RUVBL2,RPAP3,PEX3,MAPK4,RAB5C,DDRGK1,FAM241A,ADCK1,RHOH,LRRC61,HSP90AB1,RAB35,STX5,MAP3K12,GP9,PDCL,PSMC4,RABL3,SEC22B,UQCRC1,TMEM106A,ST7,YKT6,ARMCX5,FBXW7,CHMP2B,DAD1,DVL2,RPA3,MAVS,MTDH,ARFGAP3,NRP1,HSPA14,NDUFB10,MGST3,SEC63,VIRMA,CCNF,ELOVL4,CFAP298,CCDC47,MRPL11,MAP1LC3B,LBR,SEM1,DNAJC30,PSEN1,RIGI,PTGES3,SFXN1,GNG5,EMC2,POR,PSMD7,ESYT1,OSBPL8,TMEM199,CIDEB,SLC25A46,EMC4,LAMP3,SLC35A5,ARF6,TMEM45B,SRPRA,AIFM1,PTPN1,EEF1AKMT3,EHBP1,ARL10,HSD17B11,CDCA3,PSMB1,VAPB,PSMB7,PGRMC1,MTX2,OTULINL,RND2,TIMM29,PSMC1,FBXL4,PXMP2,DNAJC3,EXD2,PSMA3,CYB561,PLN,HSP90AA1,SCFD1,ILK,MTG2,VEZT,CUL3,SCN3B,RHEB,TOMM40,GGH,GPR37,GNB1,RMDN3,SEC61B,RPN1,EZH2,STIM1,VPS33A,TMEM14B,CSNK1E,MACO1,FAF2,EMC8,CDK20,PSMD12,RETREG1,TMT1A,RHOG,CDK5RAP3,RB1CC1,HAX1,PPP3CA,BCL2L1,PSMD3,FAM174A,MARCHF5,EGLN3,CACYBP,PSMB5 |
| 2.315e-10 | -22.19 | nuclear outer membrane-endoplasmic reticulum membrane network | cellular component | GO:0042175 | 1227 | 455 | 19108 | 5553 |
CCDC47,DNAJC25,TLR7,DHRS3,RDH10,MSMO1,EXT1,GJA1,CYP39A1,CYP4F12,ILVBL,PML,GGCX,TMEM39A,TMEM38B,ELOVL4,RNF133,SPCS2,STBD1,TLCD3B,PSEN2,FLRT3,RAB1B,UFD1,SPCS3,CYB561D2,OSBP,MACO1,LMBRD1,TMEM147,RDH12,IZUMO1,MRLN,DRD1,CYP2C9,LRRC8B,FITM1,FITM2,C2CD2L,ARL6IP5,ELOVL6,VAMP7,PLAAT3,UBIAD1,EMC4,SSR2,SEC63,SHISA2,PIGW,SDCBP,RSAD2,SEC11A,CYP4F22,GALNT2,SLC35B4,CIDEB,RAB6A,ERO1A,MYORG,CYP2F1,DERL2,STX5,CHRM3,CPTP,UBA52,SEC22A,CYP26A1,DHRS7B,REEP4,HACD1,FKBP2,ERG28,STT3A,EMC6,VAPB,SRXN1,RTCB,EMC1,ZDHHC4,SRD5A3,HSPA5,IFI27,FOLR1,NSDHL,ORMDL3,VMP1,SRPRB,SERINC1,CYP3A43,SLC35A2,RB1CC1,KDSR,CD59,MINAR2,TMEM97,AHCYL1,RETREG3,TMCC1,PNPLA8,WASL,SLC51A,LRRC8D,HACD2,MOXD1,SLC35B3,TMX4,REEP6,USE1,FMO2,GORASP2,TRAM1L1,PREB,RP9,ELOVL3,SRI,SCFD1,FDFT1,LRAT,CYB5R3,RNF121,PTGDS,ELOVL7,CYP1B1,ACER3,BOK,SPCS1,VTI1B,RAB18,GDPD3,TRAM2,SEC61G,DERL1,SELENOK,KPNA2,BCAP29,PCYT1B,RPL27,BSCL2,CLN8,RDH11,SEC22C,ABHD4,TAPT1,FA2H,CYP17A1,PROS1,SEC22B,MX1,JKAMP,CYP2C8,PIGA,PDIA3,EVA1A,RPN1,KDELR1,MYRF,TRAF2,FATE1,RPS26,FAM8A1,IFI6,PTDSS1,PTPN1,CYP21A2,EMC10,FKBP8,HSD17B3,RNF5,PLP2,GOSR2,CYP1A1,ANXA7,SFTPA1,SSR1,INSIG2,PGAP3,XXYLT1,TSPO2,SLC30A7,ARCN1,CYP4V2,CARD19,RNF139,GRIA1,RNF103,ALG2,CYP3A5,CYB5R4,OS9,TMED4,FAXDC2,CLSTN3,NCSTN,GRIA2,UBAC2,NOS1AP,NFE2L1,STX18,ESYT1,TMEM33,GALNT1,STIM1,TAPBP,ALG11,CYP2D6,TRAM1,RETREG1,FLRT2,RAB14,ZDHHC16,FAF2,PSEN1,WDR83OS,SPTSSB,GABARAPL2,CAMK2G,TOR1AIP2,SEC61A1,TEX264,LBR,AGTRAP,NSG1,HSP90B1,RAB9A,RINT1,SGMS2,HTRA2,SC5D,PEDS1,POMT2,SEC61A2,TMEM170A,ATP6AP2,FAF1,CERS6,ENO1,ATG9A,AGPAT1,PGRMC1,SPPL3,GPR37,HM13,DHRS4,XPO1,ACSL4,APH1A,TM4SF20,CNIH1,TLR9,RETREG2,MOSPD1,PLD3,STX17,DIO1,ZMPSTE24,SGMS1,OSBPL8,COPZ2,NUS1,SSR3,DHRS7,RAC2,PSKH1,CERS2,DPM2,SLC39A13,SEC23A,DOLK,XBP1,CASP4,LMBR1L,GPAA1,RPS28,EXTL2,GJB1,TMEM106C,ALG5,MPDU1,TLR3,PGAP2,PTPN5,SEC13,SELENOS,HRAS,ELOVL1,DPAGT1,PTGES,ERLIN1,GNAI3,UGT1A1,TMED7,CYBC1,SEC62,BAX,CNIH4,STARD3NL,AGPAT5,TMX3,BFAR,SURF4,SACM1L,PIK3R1,RTN4,ABCB9,SFTPC,SELENOI,TAPBPL,CREB3,MIA2,TMT1B,TAB1,CYB5R1,SFTPD,APOO,LRRC8C,AQP11,OTULINL,SDR16C5,KRAS,NOTCH2,MGST2,DDRGK1,CDIPT,EMC9,CYP7A1,TMX2,FMO1,EDEM1,CYB5A,CD1D,SLC30A5,SLC35D1,TMEM174,CALR,SELENOT,POR,TECR,PDIA6,CFTR,SELENON,DNAJB2,SVIP,DLG1,PIGK,RPS29,TMBIM6,CAMLG,CDK1,FKBP1B,CYP4F8,PIGY,TMEM50B,CH25H,G6PC3,YIPF5,DUOXA2,UFL1,TLR8,FZD6,KDELR2,FKBP1A,LMAN1,SIGMAR1,GJC1,CREB3L4,CYP2C18,ALOX5AP,CYB5B,TMCC2,PSENEN,CYP2R1,TMEM203,MARCHF5,PIGC,B2M,SYVN1,RIC3,RNF26,PITPNB,CALU,SAR1B,EIF5A2,SLC37A4,GABBR1,SLC39A7,HACD4,MEST,COPE,HMOX2,DMPK,TMEM14A,JPH4,BICD2,SEC61B,EI24,ATG101,DNAJB9,CD4,ERLIN2,TRIQK,SPTSSA,LPCAT3,DEGS1,TNPO3,PLPP6,MBLAC2,HSD11B1,RPS27A,VKORC1L1,RHOG,EMC2,BECN1,TMED5,OST4,ATL1,IL15RA,FADS2,ABHD12,UBB,RAB2A,TUSC3,RHEB,DAD1,ZDHHC14,DIPK1A,TEX261,RCE1,EMC8,TMED1,TMED9,HACD3,EPHX1,BET1,PYURF,YIF1A,TESPA1,FMO3,TMED3,DNAJC1,REEP3,ZFAND2B,SRPRA,MGST3,MTDH,ORMDL1,CAV1,SCD5,SYNE4,JAGN1,KCNA2,PLN,CDC42,TMEM208,RETSAT,TMEM199 |
| 2.380e-10 | -22.16 | vif (Vif) | protein interactions | 155459 | 362 | 157 | 19454 | 5460 |
PSMB6,POLR2B,RORB,EIF4E3,PSMD6,PSMD4,STAT1,APOBEC3G,HSP90AA1,ICA1,FGFBP2,CD226,CCT2,PSMD1,IRF1,CUL2,APOBEC3B,TNFSF10,CCR7,PSMC1,HADHA,PSMA3,C1D,HSPA8,SAT1,TLR5,RNF7,IL4,APOBEC3C,PSMB7,PPARG,GLRB,APOBEC3A,CDKN1A,PSMB3,PRKAB1,CSF2,CCT7,PPIA,TCP1,CCAR2,HNRNPL,IL10,MAP1LC3A,PSMB4,TRAF3IP3,PSMB5,PSME2,CBFB,WDR6,HSPB1,DCAF11,SLC25A21,PSMD10,IFNB1,SPON1,PPP2R5A,PSMD3,PRPF19,IFNG,PSMD12,SRSF4,HNRNPF,PSMA2,ZBTB16,PLCB1,CCT8,HNRNPA2B1,HSPD1,RND3,PRKAG1,TAS2R40,ERRFI1,TRAF1,CXCR3,UBB,IFNA10,PLAGL1,CEBPE,PSMC5,EIF2AK2,PSMA6,CCL1,STUB1,TNFSF15,RUNX1,PRKACB,CCNB1,CYRIA,PSMB2,ATG4C,CCR4,HDAC3,LITAF,SQSTM1,MNS1,IRF3,MME,RHOU,TRIM36,PRL,UBE2F,RPA2,CDK1,HPS6,RSAD2,PSMC4,MDM2,CDK9,GSTA4,CAND1,CD4,LDLR,AIFM1,PDE9A,ITGA6,IFNA2,AKAP8L,TNFRSF14,DNAJC7,PSMD7,NR4A2,LY96,APOBEC3F,ELOC,HDAC6,GRAP,TLE1,XAF1,DNAJB2,PSMB10,ATG4A,NEDD8,PSMA5,TNFSF8,HUWE1,DHX9,IFNA13,ABCE1,PSME1,SPSB1,MAP1B,SPRY1,PSMC3,SOD2,RBM34,TFRC,SMAD1,APOBEC3H,MAP1LC3B,DUSP1,APOBEC3D,FGL2,TP53,CCT5,UBL4A,TBK1 |
| 2.406e-10 | -22.15 | RPS10 (ribosomal protein S10) | protein interactions | 6204 | 536 | 217 | 19454 | 5460 |
AGR2,DRG1,BAZ1B,DDX50,WWP2,RPL6,CPEB1,XPO1,CTNNB1,DDRGK1,NGDN,SNRPA1,SRSF1,EED,GLE1,RPS23,RPL18,TOP3B,H1-3,RPS7,H1-6,PSMA1,KRAS,RPS4X,RPL28,RPL31,RPAP3,EWSR1,FBXW11,H1-10,RPS26,NSA2,H1-1,MYC,SFN,BTF3,TRIM29,RPL10,CMTR1,EIF4B,PIH1D1,SYK,TOMM22,RPL27A,UFL1,STAU1,PYM1,RPS28,SF3B1,TUBG1,RPL24,SNRNP70,NOL12,RPS2,RPL10A,RBM17,COPS5,CSNK2A1,RPS16,CAND1,FZR1,DKC1,RBM42,SURF6,CDC5L,CD4,TFCP2,DNAJC2,IMP3,UBL4A,RPSA,TP53,H2AX,NEDD8,IMP4,MEPCE,SRSF12,RPL17,RPL3,SPOP,RAP2C,RC3H2,CHCHD4,PTTG1,UBE2H,RRP7A,RPL7A,RPS17,ZSCAN25,ST13,ADRM1,RPL10L,SMURF1,SRPK2,RSL24D1,RPS3,PSPC1,FGFBP1,EIF2S2,MACROH2A1,RPA2,HEXIM1,ZNF770,KLF4,CFTR,RPS15,ZC3H15,HSPA5,RPL27,BAP1,PML,EXOSC4,RNF113A,CDK5RAP3,AHSA1,RSBN1L,RPL23,PRPF19,RPL7,CCAR2,RPL8,RPL9,PHB1,RPLP1,HP1BP3,RPLP2,CHMP4C,RPS11,E2F4,PPP2R1A,TNF,G3BP1,DMPK,RPS27A,SRSF4,RAD21,TRIP4,RPS24,ZCRB1,RPS5,SP1,RIT1,CBR3,CUL3,NOP16,ZNF668,RPS29,RPF1,RPL35,RPL7L1,RPL19,ZNF22,EIF3K,RPL37A,SEC61B,RPS9,PSMB7,ATP5PO,WDR77,H1-5,NRDE2,NOP53,YTHDF1,G3BP2,CCDC86,MPHOSPH10,MOV10,NFKB1,CDC37L1,SPATS2L,HDAC6,RPL35A,DCUN1D1,CDK9,RPL12,RCHY1,KRR1,PRR3,SRP72,FBP1,APOBEC3D,RPL15,PAK1IP1,HUWE1,FBXO25,RPS13,EIF3E,NKRF,RPL23A,CDC73,PPP1CC,USP14,NONO,RPL13A,VIRMA,SEC63,RPL22,CCNF,METAP2,RPS20,RPS12,GRM2,RPL26L1,RPLP0,ZNF574,RPS14,RPL4,HMGB1,FBXW7,PIK3R2,AATF,UTP23,MME,RPA3,SIRT7,PRPF4,PPIH |
| 2.423e-10 | -22.14 | endoplasmic reticulum subcompartment | cellular component | GO:0098827 | 1209 | 449 | 19108 | 5553 |
MRLN,IZUMO1,OSBP,SPCS3,CYB561D2,TMEM147,RDH12,MACO1,LMBRD1,UFD1,RAB1B,EMC4,SSR2,SEC63,VAMP7,UBIAD1,PLAAT3,FITM2,ELOVL6,C2CD2L,ARL6IP5,LRRC8B,DRD1,CYP2C9,FITM1,GJA1,EXT1,CYP39A1,CYP4F12,RDH10,MSMO1,DHRS3,CCDC47,DNAJC25,TLR7,TLCD3B,FLRT3,PSEN2,SPCS2,RNF133,STBD1,GGCX,TMEM39A,TMEM38B,ELOVL4,PML,ILVBL,RETREG3,TMCC1,AHCYL1,TMEM97,WASL,PNPLA8,KDSR,SLC35A2,RB1CC1,CD59,MINAR2,CYP3A43,VMP1,SRPRB,SERINC1,FOLR1,NSDHL,ORMDL3,RP9,ELOVL3,SCFD1,SRI,FMO2,TMX4,REEP6,USE1,PREB,GORASP2,TRAM1L1,SLC35B3,MOXD1,LRRC8D,HACD2,SLC51A,MYORG,ERO1A,CYP2F1,DERL2,RAB6A,CIDEB,GALNT2,SLC35B4,SDCBP,PIGW,SHISA2,SEC11A,RSAD2,CYP4F22,EMC1,ZDHHC4,RTCB,SRXN1,IFI27,SRD5A3,HSPA5,DHRS7B,STT3A,EMC6,VAPB,HACD1,FKBP2,REEP4,ERG28,SEC22A,CYP26A1,STX5,UBA52,CHRM3,PDIA3,EVA1A,PIGA,RPN1,JKAMP,CYP2C8,CYP17A1,SEC22B,PROS1,MX1,EMC10,CYP21A2,HSD17B3,FKBP8,PTPN1,IFI6,PTDSS1,FAM8A1,RPS26,TRAF2,KDELR1,MYRF,FATE1,SPCS1,VTI1B,BOK,ACER3,RAB18,ELOVL7,CYP1B1,LRAT,RNF121,CYB5R3,PTGDS,FDFT1,ABHD4,TAPT1,FA2H,RDH11,RPL27,PCYT1B,BSCL2,CLN8,SEC22C,SELENOK,KPNA2,BCAP29,SEC61G,TRAM2,GDPD3,DERL1,SPTSSB,GABARAPL2,FLRT2,RETREG1,WDR83OS,PSEN1,ZDHHC16,FAF2,ALG11,TAPBP,TRAM1,CYP2D6,ESYT1,STX18,GALNT1,TMEM33,STIM1,HSP90B1,NSG1,AGTRAP,LBR,TEX264,CAMK2G,TOR1AIP2,SEC61A1,ARCN1,XXYLT1,SLC30A7,TSPO2,CARD19,RNF139,CYP4V2,INSIG2,SSR1,PGAP3,CYP1A1,SFTPA1,ANXA7,GOSR2,RNF5,PLP2,NOS1AP,UBAC2,NFE2L1,GRIA2,CLSTN3,NCSTN,CYB5R4,OS9,ALG2,CYP3A5,FAXDC2,TMED4,RNF103,GRIA1,DOLK,SEC23A,SLC39A13,XBP1,PSKH1,SSR3,RAC2,NUS1,DHRS7,CERS2,DPM2,OSBPL8,COPZ2,DIO1,STX17,PLD3,SGMS1,ZMPSTE24,PTGES,SELENOS,SEC13,PTPN5,DPAGT1,HRAS,ELOVL1,MPDU1,ALG5,PGAP2,TLR3,LMBR1L,GPAA1,CASP4,TMEM106C,GJB1,RPS28,EXTL2,ATG9A,CERS6,PGRMC1,AGPAT1,ATP6AP2,TMEM170A,FAF1,POMT2,PEDS1,SEC61A2,RINT1,RAB9A,HTRA2,SC5D,SGMS2,TLR9,RETREG2,MOSPD1,TM4SF20,CNIH1,ACSL4,APH1A,GPR37,SPPL3,HM13,DHRS4,FMO1,DDRGK1,CDIPT,MGST2,CYP7A1,TMX2,EMC9,SDR16C5,NOTCH2,KRAS,OTULINL,AQP11,APOO,LRRC8C,CFTR,PDIA6,SELENON,CALR,SLC35D1,TMEM174,TECR,SELENOT,POR,CD1D,SLC30A5,EDEM1,CYB5A,BFAR,SURF4,AGPAT5,TMX3,UGT1A1,TMED7,CNIH4,STARD3NL,CYBC1,SEC62,BAX,ERLIN1,GNAI3,CYB5R1,SFTPD,TAB1,TMT1B,PIK3R1,ABCB9,RTN4,SFTPC,MIA2,TAPBPL,CREB3,SELENOI,SACM1L,EIF5A2,RNF41,SAR1B,CALU,SLC37A4,RNF26,SYVN1,RIC3,PITPNB,PIGC,B2M,MARCHF5,TMEM203,DNAJB9,CD4,TRIQK,ERLIN2,LPCAT3,SPTSSA,SEC61B,EI24,ATG101,JPH4,HMOX2,COPE,DMPK,TMEM14A,GABBR1,HACD4,MEST,SLC39A7,CDK1,TMBIM6,CAMLG,RPS29,PIGK,DLG1,SVIP,DNAJB2,GJC1,CREB3L4,CYP2C18,SIGMAR1,TMCC2,PSENEN,CYP2R1,ALOX5AP,CYB5B,FKBP1A,KDELR2,TLR8,FZD6,LMAN1,DUOXA2,UFL1,YIPF5,G6PC3,TMEM50B,PIGY,CH25H,FKBP1B,CYP4F8,REEP3,TMED3,DNAJC1,ZFAND2B,TESPA1,FMO3,BET1,PYURF,YIF1A,HACD3,EPHX1,TMED1,TMED9,RETSAT,TMEM199,CDC42,TMEM208,CAV1,SCD5,KCNA2,PLN,JAGN1,MGST3,MTDH,SRPRA,ORMDL1,TMED5,OST4,ATL1,VKORC1L1,EMC2,BECN1,RHOG,MBLAC2,PLPP6,HSD11B1,RPS27A,DEGS1,RCE1,EMC8,RHEB,TUSC3,TEX261,DAD1,DIPK1A,ZDHHC14,UBB,RAB2A,IL15RA,ABHD12,FADS2 |
| 2.437e-10 | -22.13 | HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2) | protein interactions | 3188 | 292 | 132 | 19454 | 5460 |
PPT1,WDR77,INPP5E,ARHGEF39,STAU1,PRCP,UFL1,HNRNPA0,UCHL3,MIR106A,DDX5,PSMA3,HSPA8,HDAC5,CRY1,BRCA1,FBXW11,PSMD14,CIRBP,SERPINH1,MIR363,PYCR1,CUL3,CUL2,PRMT6,MYC,APOBEC3B,MCM3,MIR98,PRPF31,TENT5C,MATR3,CLIC4,MIRLET7D,MIRLET7B,CHMP4C,CRKL,PLD3,MAX,MAK16,SOX2,MIR222,MIR155,HNRNPF,G3BP1,HNRNPDL,RAD21,HNRNPA2B1,MIR9-2,MIR206,MIR31,HSPB1,MIR140,MAGOH,DDX1,HNRNPD,MIR1-1,MIR221,MIR143,DDRGK1,MIR29C,HNRNPA1,MIR9-1,SUMO2,KCTD10,MIR7-2,PHB1,MIR214,MIR141,EED,MIR7-1,HNRNPH3,HEXIM1,MIR21,WDR83,MIR34B,RBFOX2,CFTR,MIR1-2,AGO1,FBXW7,MIR7-3,NF2,MIR29A,MIR107,HSPA5,MIR205,MIR34C,HNRNPH2,MIRLET7I,MIR145,RC3H2,AR,FBXO7,VIRMA,SRPK2,SMURF1,EIF4A3,OPTN,CCNF,MIR16-1,UBASH3B,QSER1,MIR17,MIR20A,NUPR1,UBL4A,MIR15A,MIR200C,HNRNPK,NEDD8,MIR16-2,MEPCE,MIRLET7C,PQBP1,MIR200A,MIR9-3,ERO1A,SNRNP70,MIR34A,ISYNA1,MOV10,COPS5,MIRLET7G,CAND1,DCUN1D1,FZR1,MIR429,MGME1,MIR106B,SYNCRIP,MIR25 |
| 2.463e-10 | -22.12 | HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta) | protein interactions | 3032 | 428 | 180 | 19454 | 5460 |
TP53,MTCH2,FURIN,RNF8,SLC25A24,NUPR1,TNNI3K,RELL2,CDH8,TFCP2,MAP1B,MEPCE,CAMKV,COX5A,FAM20C,USP15,MAP4,TUBG1,COX4I1,MALSU1,MYL12A,TMED9,ARL6IP5,DNAJC1,FZR1,SPPL3,CDC42,CYC1,UBE2M,FGFR1,RPA2,HSPB2,PML,HSPA5,CALU,ATP1A1,CHCHD4,DNAJC10,SPOP,PHAX,UQCRC2,RALA,DNAJC25,TOP3B,PDHA1,RUVBL2,VDAC1,DDRGK1,CCL11,WWP2,ZCCHC10,AGR2,CORO1C,YBEY,SDC4,HSP90AB1,SYK,SYNDIG1,SDC2,EP300,COX17,MRPS7,PHB2,ADRB2,NDUFS2,UFL1,PCCB,BTF3,ATG101,MYC,ZMPSTE24,ICAM1,LAMTOR1,SMU1,VDAC2,LMBR1L,DES,ESR2,TAX1BP1,ATP5F1B,CAVIN2,AURKAIP1,MAP1LC3B,TBK1,FBP1,NDUFS3,EMC2,HSD17B10,GNG5,SFXN1,RAB1A,SMN1,ABHD10,RNASEL,GALNT2,THRAP3,HUWE1,ATP1B1,HDAC6,CCR6,ATP5MG,CALR,ASIC2,ESYT1,RCHY1,TIMM8B,PRNP,GABARAPL2,UQCRC1,SEC22B,HSP90B1,COX6C,SPCS2,RTN4,SQSTM1,PPM1G,RPA3,MME,DVL2,SMC4,PDHB,ATP5F1A,RALB,NDUFB10,CSK,DNAJC19,CASC3,GANAB,GNAI2,UQCRQ,MGST3,GABARAPL1,ACTN4,CYB5R1,RAF1,B3GNT2,EZH2,RPN1,ERP29,COX8A,NDUFA4,HSPD1,STOML2,PDIA3,HNRNPD,MED4,RHOG,ATP6V1A,COPS2,CETN3,MAP1LC3A,PHB1,NDUFS8,EGLN3,RAB6A,CDKN1A,PRDX3,TOR1AIP2,NDUFA5,SLC25A3,ANXA7,MED23,ATP5PO,CFDP1,PSMA3,HADHA,ATP5MK,CXCR4,GPC1,UCHL3,TOMM40,RFC5,CUL3,NTRK3,CDC7,CYB5R3,GNB1,RPL35,RPL7L1,ACTB |
| 2.473e-10 | -22.12 | NPC1 (NPC intracellular cholesterol transporter 1) | protein interactions | 4864 | 348 | 152 | 19454 | 5460 |
TRAM1,CDC42,GABARAPL2,TPRA1,SLC35F6,SYNGR2,SEC22B,EPHX1,SDCBP,LMNA,COX6C,STOM,WWP1,SSR1,GP9,GPR35,SYVN1,VIPR1,SPCS2,MTDH,RAB9A,ARPC2,RTN4,NR1I3,TMX2,APMAP,PIP4P1,DNAJC5,RAB2A,RETSAT,CSK,LRP6,ATP1A1,ABCG2,SDF2L1,ATP1B3,LGALS8,B4GALT1,MRPS28,TRIM27,SELENOT,UBB,VIRMA,GNAI2,DYRK1A,ACP2,PNP,TMOD3,RALA,BUB3,RAB14,APOO,GDE1,CCDC47,GNAI3,PSMC3,SIGLECL1,TLR3,ACTR2,LPAR2,SLC16A1,EMC2,RAB1A,STX8,ARF4,CAPZA1,GALNT2,RIGI,ERLEC1,PSMA5,L1CAM,SRPRB,RAB22A,CSNK2A1,ATP1B1,LAMTOR2,EDEM1,TMEM184C,SLC2A1,POR,ESYT1,SEC23A,STT3A,HACD3,TMPO,SLC38A2,TMED9,VTI1B,DERL2,PPP1CB,RAB6A,AGTRAP,PGRMC1,NUFIP2,UBAC2,SIGMAR1,HSPA8,ATP2C1,TMEM106B,WBP2,STX7,GNB4,ATP6V1G1,EMC1,HSCB,RER1,TMED5,LAMTOR1,SPCS3,ATG3,SLC30A7,AP2M1,LMBR1L,S1PR4,CYB5R3,LAMTOR3,RBBP4,SNRNP40,FAF2,TMBIM1,NCSTN,SPG21,LGR4,ERLIN2,B3GALT4,TOP3B,STX12,SNRPE,RPN1,RAB4A,MYO1B,CCDC32,VAMP8,AP1M1,FLOT1,RAB18,RAP2B,FAM20B,LAMP2,RAB32,RAB5C,TMEM30A,VPS4A,ITPRIPL2,CORO1C,TSG101,ATP6V1A,MPDU1,VAMP7,RAB1B,BUD31,SNRPA1 |
| 2.486e-10 | -22.12 | PSMD2 (proteasome 26S subunit ubiquitin receptor, non-ATPase 2) | protein interactions | 5708 | 405 | 172 | 19454 | 5460 |
MOV10,TPM3,ZFAND2B,PPM1D,HDAC6,ECD,PSMD7,CCDC92,MAP4,USP15,SYNCRIP,AIFM1,PSMB1,LDLR,PRNP,FZR1,ASB11,CDC5L,TMPO,MDM2,TP53,PSMB9,TMEM31,RAD23B,ZFAND2A,PSMC3,APEH,PSME1,MAP1B,PSMA5,HUWE1,SEM1,RIGI,FKBP8,EGR1,PSEN1,MEPCE,VTA1,FBXO25,GJB2,PSMB2,AR,USP14,RC3H2,SPOP,UBE2H,CDC73,ATP1A1,PDCD4,PSMA6,STUB1,CCNF,RPS12,PTEN,PSMC5,ADRM1,COPE,DUSP3,VIRMA,SMURF1,UBE2L3,SUMO1,PSMC4,ATG16L1,UBLCP1,PAAF1,CFTR,NEK2,GRM2,JKAMP,HSP90B1,RPA2,ACACA,HECTD1,UBE2M,HEXIM1,PML,SIRT7,NBN,IDH3A,PRPF4,BAP1,RPA3,SOD1,PPM1G,DERL1,SQSTM1,SYVN1,SMC4,HMGB1,ATG4C,EIF4E,DIRAS2,PSMD3,UBXN6,IFI16,DDRGK1,ATG7,YWHAH,AGR2,PSMD10,NQO1,CDKN1B,POU5F1,AHSA1,PSMB5,PSMB4,PSME2,GJA1,CCAR2,EGLN3,DIRAS3,ERLIN2,GFPT1,ISG15,PPP2R1A,SOX2,FAF2,EZH2,TRIM11,UBE3A,RUVBL1,ZBTB16,G3BP1,PSMA1,KRAS,PSMA2,RBBP7,RAD21,CPLX1,RPS27A,PSMD12,PSMA4,CUL3,MYC,UFD1,BAG3,PSMD1,BTF3,PSMD14,BRCA1,POMP,CCT2,LMBR1L,SRXN1,PRMT5,PSMD6,PSMD4,ESR2,LRIF1,PSMB6,PSMB3,GJC1,CDKN1A,PSMB7,PIH1D1,HERC3,PSMA3,EP300,HDAC5,HSPA8,TXNL1,ADRB2,NSFL1C,STAU1,PTN,UFL1,CYFIP2,PSMC1,RNF11,DDI1,ZBTB39 |
| 2.491e-10 | -22.11 | H2AX (H2A.X variant histone) | protein interactions | 3014 | 548 | 221 | 19454 | 5460 |
SUPT5H,MAGEB10,HEXA,ERRFI1,PAIP2B,MTA2,SMARCB1,PABPC1,PDIA6,RUVBL2,NUP42,RUVBL1,H1-6,PELI1,HNRNPDL,RPL6,BAZ1B,IFI16,DIS3L,STK4,H2BC17,YWHAB,ANXA4,SIN3A,RPS10,PAIP1,HMG20A,MACROD1,TOR1B,PSMB3,CTBP1,XRCC5,RPS28,EP300,YAF2,P4HA2,TIFA,EYA3,STAU1,MRPS7,GINS3,LDHB,HNRNPC,HNRNPAB,BTF3,RBBP8,SURF2,PHF21A,MCPH1,ZMYM2,TRIM29,MATR3,ESR2,CBX5,TP53,ZMYM3,H2AX,CAPZA2,TP53I3,CBX3,BIRC5,NUPR1,RNF8,DHX9,ERO1A,H3C1,H2BC14,MEPCE,ENY2,CSNK2A1,PPM1D,H2AC4,NPSR1,AGPAT1,RPS2,ALYREF,COX4I1,SYNCRIP,EEF1B2,SSBP1,FZR1,RPS16,DKC1,AGO1,H2BC11,WRAP53,RPA2,ACACA,HEXIM1,THUMPD1,NBN,PML,PRDX6,PGK1,RPS15,HSPA5,CLU,RPL7A,SMARCA5,ZSCAN25,CFL1,H2BC9,ELAVL2,LIG3,RPS3,MACROH2A1,EIF2S2,IFI6,TXNDC12,DYRK1A,B3GNT2,ANP32A,CHMP4C,SNRPE,HNRNPA2B1,FGF3,MORC2,ERP29,ZBTB14,ZNF592,SSRP1,MCM6,RPS27A,MRPS35,HMGA1,HNRNPA1,TRAF6,KDM2A,DDX23,ZCCHC9,HNRNPD,PSMB4,RPL8,RPLP2,MAP1LC3A,CETN2,RAB11B,PPIA,PRDX3,ADNP,FKBP10,CCDC86,MCM4,SMARCE1,ZNF668,YWHAZ,BRCA1,RPS5,HSP90AA1,RAN,PARP2,ZNF22,RPS9,ACTB,SNRPB2,RPL19,MAD2L2,CCT5,MTA3,EEF1A1,DMAP1,LLPH,GINS4,ZFAND2A,RAD23B,ILF2,TOPORS,SOD2,HSD17B10,RPL23A,RING1,HUWE1,RNF115,CTNNBL1,MSH6,ABHD10,PRDX4,MDC1,CALR,UQCR11,BRD3,KRR1,H2AZ1,AIFM1,CDK9,TPT1,ATG16L1,METTL14,HSP90B1,P3H1,LMNA,ZNF574,RPLP0,RPL26L1,HNRNPH3,SIRT7,PPM1G,RPA3,PRKCB,RPL4,FBXW7,NPM3,CXXC1,PIAS1,MBD3,ZNF687,TAF5L,CTSD,NONO,USP14,RPL26,STK11,ENO1,PELP1,MSN,PTEN,CMBL,PRKRA,GANAB,SCML2,UBB |
| 2.512e-10 | -22.10 | CRYZ (crystallin zeta) | protein interactions | 1429 | 156 | 81 | 19454 | 5460 |
MRPS9,MRPS23,NDUFS8,SPTAN1,GAPDH,NDUFV2,MMUT,MRPS35,NQO1,MT1X,MRPS26,AK2,HINT2,MRPS18B,ATP5PF,PREPL,MPST,FKBP2,MRPS17,ETFA,KGD4,MRPS33,BCS1L,PPIF,GLRX5,ASPM,ETFB,TXNRD1,RAF1,ATP5PB,NDUFA12,NDUFS3,ACOT13,ZNF526,NDUFS6,NEFL,PDHA1,NUDT19,PIR,ACAT1,MRPS28,CAB39,SMAP2,DLST,TACO1,NDUFAF4,CLIC4,TUBB,LGALS3,PRDX2,AKR1C2,TUFM,MTPN,PMPCA,PYCR2,PYCR1,MTG2,CSK,FXN,MRPS25,MRPS16,DLAT,PRDX6,ATP5IF1,HSPA8,RPA3,SOD1,CRYZ,MRPS7,RPL4,NDUFS2,YKT6,NME4,SPR,LAP3,NDUFA5,DCTD,GSTP1,MRPS34,KLF3,RPA2 |
| 2.513e-10 | -22.10 | regulation of angiogenesis | biological process | GO:0045765 | 355 | 160 | 18204 | 5365 |
DDAH1,MIR205,MIR495,FGF16,IL1B,CD40,MINAR1,EPHA2,KLK3,CXCR4,ITGB8,EMILIN1,SEMA5A,RHOB,GREM1,MTDH,ZNF304,MIR361,MIR23A,TNF,PDCD10,MIR505,SPRED1,CCR3,ROCK2,IL10,MIR640,MIR24-1,TGFB2,MIR1298,IL1A,CCM2,CX3CR1,MIR145,GLUL,TNFAIP3,CTNNB1,ADAMTS1,CCL24,GHRL,MIR20A,MIR214,MIR17,PROK1,PRKCA,MIR377,XBP1,SLC12A2,MIR222,CYP1B1,RLN2,AGGF1,GADD45A,MIR221,MIR130A,CCR2,FOXC2,MIRLET7B,TGFBR2,NINJ1,MIR492,MIR378A,MIR29C,CHI3L1,ATP2B4,SMAD1,CXCL10,NRP1,FGF1,MIR125A,JMJD8,PML,STAT1,PRKCB,MIR16-1,HGS,TERT,CD34,MIR424,TNFSF12,PRL,VASH1,MIR99B,MIR1224,FUT1,MIR885,MIR132,MIR34C,AKT3,MIR10A,KLF4,CCL11,VEGFC,APLNR,FASLG,LEP,KRIT1,EMC10,MIR939,PIK3CG,IL17F,CXCL8,EFNA3,MIR34B,MIR106B,FKBPL,MIR185,TLR3,SYNJ2BP,IL6,MIR1-1,MIR126,SFRP1,ROCK1,MIR143,HSPB1,AGO1,MIR15A,BTG1,CAMP,MIR34A,EMP2,ADM2,RUNX1,MIR193A,NR2E1,GAB1,RHOJ,BRCA1,JAK1,RGCC,MIR30E,MIR31,GPNMB,JUP,NIBAN2,MIR503,PPARG,STIM1,MIR212,CXCL13,PGK1,MIR375,SP1,MIR146A,MIR30A,MIR21,MIR30B,MIR137,TSPAN18,NFE2L2,HSPB6,MECP2,CMA1,MIRLET7G,VEGFA,MIR210,CHRNA7,GTF2I,MIR29A |
| 2.531e-10 | -22.10 | positive regulation of metabolic process | biological process | GO:0009893 | 3796 | 1276 | 18204 | 5365 |
XRCC5,CYRIB,TBK1,VIP,STAT5A,FAM161A,PIAS1,DIRAS1,RNF10,VAMP3,AKAP8L,MIR373,MIR183,MYLIP,RARRES2,TLR2,CYP1B1,ZNF287,APOBEC3A,MRPL12,SERTAD3,DCUN1D3,PIH1D1,MIR16-1,RDH10,POU1F1,NUP62,ARL2BP,MAPKAPK5,WBP2,PDE2A,IGF2BP1,MAP2K6,CCL2,CHCHD2,CLEC9A,SEMG2,PSMC5,PHF23,ALKBH4,APOBEC3C,CREB3,STK11,MED22,TRIM5,NME2,FBXW7,PRDX6,FOXA3,HDAC6,SGF29,NOG,S100A8,TESC,EAF2,PRR5L,ACVR1B,MED10,BOLL,CD40,FGF16,PITHD1,SYK,HILPDA,PSMC1,NR1I3,NLRP1,SERTAD1,PRKAB1,LAMP3,MED23,STAR,LACRT,EGLN3,CNOT6L,PSMC4,BIRC2,YES1,UBE2L3,TNRC6C,TRMT112,TRIM32,MED9,TCEA1,MIR101-1,WEE2,SPTBN1,DCUN1D5,NIF3L1,CD2,VSIR,CCNB1,TRUB1,CAMK1,ELK4,DEK,SOX14,TCP1,CAPN2,FZD4,NIBAN2,BSCL2,CCL1,OSM,PIK3R1,NR2E1,PIK3R2,SETD4,CUL3,KLF1,CCAR1,IL23A,MTA2,VEGFA,SLC38A2,FGF23,EIF3E,MTPN,PRELID1,BCL9,ALPL,FABP5,NSMCE3,TLR1,IL15,MIR769,MIR137,PIK3CG,PDE4B,HNRNPA2B1,TFEB,MIR140,FASLG,CD40LG,RNF41,CD58,ASB11,ELK3,UQCC2,WRAP53,CSH1,RB1CC1,IL18,CAMP,MIR15A,ETV6,ROCK1,CACUL1,SUPT4H1,NTF4,TCIM,APEX1,ELOVL3,TAF10,IL17F,HNRNPAB,UBE2D1,AR,SOD1,CCND1,MIRLET7B,TGFBR2,IL2,MIR130A,CYTL1,PAK2,FAS,PID1,ANP32B,KIT,XBP1,MET,TOLLIP,MIR320A,RGMA,DIO2,ATF1,CDK5RAP3,EGLN2,PRKCE,NR1H2,MIR125A,FGF1,NRP1,PCSK9,E4F1,TAF11,CCT7,RPL26,MIR211,ITGA2,SERTAD2,RPS4X,IFNA13,SLCO3A1,AGR2,FUBP3,TLR6,EXOSC8,DYRK1B,AKT1,AIFM1,TGFB3,IL1B,ELAVL4,MIR182,SLC45A3,CEBPE,FAM107A,PPP3CA,WNT7A,VSTM2A,NEUROD6,TEF,CREB3L4,MT3,CCND3,TOX,OXTR,RBBP4,TNFAIP3,GH1,MAX,GSTP1,VDR,TXN,BAK1,TCF23,SNX18,GRSF1,MIR675,SIRT7,CALR,NSG1,DKC1,ROMO1,APH1A,HMX2,NFKBIA,IGF1,UCP2,CNOT2,ENY2,MEF2B,CDC73,ZNF507,UBE2S,TNIK,IFNA2,MIR96,DNAJB2,PPP1R10,DNAJC3,FABP4,LCP2,EHD4,PPP2R5A,ZBTB16,ZNF24,MCL1,TNFRSF1B,SMARCD3,PLCB1,TLR9,IFNK,ATG7,ADM2,HDAC3,MLLT6,TP53INP2,MED27,GTF2A1,PRKAG1,UCN,GABPB1,OPTN,BABAM1,CD80,MIR423,MIR204,CLEC6A,NMI,DSTYK,WNT10B,SSBP3,MAD2L2,SMYD3,PAX6,RIGI,TENT4A,SMARCE1,SLX1A,KLHL25,MIR130B,BVES,PRNP,HAX1,E2F4,CLIP3,PAFAH1B2,SF3B4,CD274,FOXP3,UHMK1,ACTL6A,PPP1R12A,AKT2,PAIP1,IFNA10,CD86,MMP9,GADD45G,PADI2,SOX21,ADIPOR2,TRAF3IP2,BAX,TP53INP1,ID4,TOM1L1,AGPAT1,MOB3B,EFCAB7,IL6,ELF1,UBE2K,FCER1G,DDX1,MMP14,MAGEC2,ACVR1C,MIR223,ZNF513,CTSD,NEUROG2,CLDN3,IRF4,FOXC2,AIF1,NLRP3,CEBPG,CNTN1,ZBED4,GJA1,MIR214,MIR17,TNFAIP1,SLC25A5,NLRP2,RB1,CITED1,RNF152,ILK,TAFAZZIN,NDN,CDK9,TMSB4X,CDKN1A,TENT5C,SUPT5H,NFYA,MED4,CCT8,LURAP1,IL1RAP,MZB1,GTF2A2,MIR98,MED11,EMILIN1,OAZ2,ITGB8,ABHD5,HINFP,HFE,CLDN4,PLAC8,SH3BGRL,FGF7,TOP2B,ORMDL3,STUB1,DDAH1,MID1IP1,PDE12,RUVBL1,ING1,PHB1,AVPR1B,SLC25A4,FCGR2A,MIR191,NGRN,CX3CL1,RBPJ,SF3B1,XCL1,MUL1,HMGA1,ACTB,FGF3,TNF,PSME2,EPCAM,SGTA,UFL1,RBM3,MIR212,FOXJ3,RHOG,TRA2A,PLGRKT,TRIM52,CDKN1B,PRIM2,LHX2,GTF2I,HEXB,DROSHA,FAF1,MIR195,B2M,RBCK1,TRIM44,TRIM15,APOC2,RNF139,DET1,HMCES,C1QTNF1,KPNA2,LUM,ZNF668,ARF4,JADE1,DLG4,APLNR,TLR4,ZBED3,KLF4,PAX9,GHR,BAG2,PTPN1,HSPA8,CSRNP3,RAP2C,MIR99B,CNOT8,MIR26B,ZNF574,TRIP4,ZNF473,MGMT,NCBP2,SOD2,NEK7,LEPR,OAZ1,MIR1-1,SOST,GNAI3,STK4,TP53,ACTL6B,SDCBP,MIR188,TNFSF10,MDM2,DNAJB9,RBM23,DLG3,CNOT6,SF3B5,TOPORS,BECN1,HBB,FIS1,BAG3,NDFIP1,STAT2,SOX9,PAEP,HOXC4,HNRNPA0,CSNK2A1,RGN,GHRL,SUB1,NUCKS1,FCGR1A,ANKRD49,STPG4,HGS,IRF8,PRMT2,MIR511,MAP2K1,HDAC5,CDC5L,PRPF19,NR1I2,KDM1A,EDF1,IL5,RGMB,BUD23,ZBED1,TLR7,C9orf72,MBD3,PRDM4,HAND2,ZNF345,ADRB2,HCFC2,UAP1,CCR7,STAT6,ISG15,RNF8,DHX9,DKK1,RAB1B,BTBD10,SPP1,HOXB1,MSL2,RFC2,TLE1,SCAND1,MIR9-1,TRIM8,RPRD1B,LTB,PAOX,SESN3,RAB29,RERE,ZFAND2A,MAP2K3,OSBP,MIR192,LRP3,PARM1,ARPP19,NLRP9,NKRF,CD81,DGCR8,MIR146A,MIR149,CD46,FAM98A,MYD88,TAF5L,ILF2,NPTN,IL4,HTRA2,MDC1,HSPA5,SOCS5,IL20RB,RUVBL2,USP5,EFNA5,ING2,TADA1,MAVS,ZBTB17,KANSL3,FURIN,EEF1E1,GPBP1L1,TYROBP,SETD7,KLF12,GTF2F2,IL6ST,RFX4,CSF2,MAP3K12,IRF3,HEY2,BARX2,IL12A,BCL10,MIR132,LILRB1,TPD52L1,RWDD3,EIF5A2,YWHAH,HNF1B,CCL3,MIF,CDC42,FZR1,PPIA,DUSP19,LRRTM3,AGO1,NUPR1,CSNK1E,FERMT2,RCHY1,FLCN,SFRP1,IGF1R,RTRAF,DYRK2,AKAP12,MOSPD1,DEFB124,EPHA4,TLR3,TRIM68,PELP1,EFNA3,RORB,CCL5,TRIB1,RNF40,TMEM59,PLAGL1,CCL19,TLR5,GADD45A,TRAF6,FXR2,NDP,TICAM2,MIR181D,CD38,NEK2,LIPT2,PABPC1,PLP1,SUPT3H,HLF,ARG2,TESK1,CRADD,MIR491,TERT,NFKB1,WBP1L,PML,FAM168A,IRF2BPL,TFCP2,BMPR1B,CHI3L1,DISC1,FOS,HCLS1,ADIPOR1,STAP1,ATF3,NKX3-1,PKNOX1,RPS7,FCGR2B,RALB,MED30,KLF10,CLU,MIR205,TRIM62,SELENOK,TFRC,TUSC2,TAF9,RHBDD3,HNRNPD,WNT2,EIF4A3,RAP1A,KMT5B,SMAD3,CRTC2,ISCU,MIR24-1,CSRNP1,PCBD1,ATG16L1,RFXANK,METTL14,ACTR2,EIF2B5,NBN,TLR8,IFI16,NTRK3,ZNF319,CCDC3,LMO3,CCT5,DDAH2,NTRK2,STARD4,IRF1,BRMS1,PQBP1,AFAP1L2,UTP15,MIR625,MIR100,BNIP3L,MIR29A,EXOSC3,BMPR2,TFE3,SEMA7A,MIR181C,BMPR1A,SMARCB1,MECP2,SMAD9,MPV17L2,AKR1C1,NFE2L2,TICAM1,SOX3,FBXO7,ATF4,CD200,TRIM21,LEP,HNRNPK,SQSTM1,POLR2G,ZNF175,PHB2,SRC,SH3BP4,ANGPT1,ZNF609,SMARCA5,SUMO2,TNFSF12,PTGES3,FAM162A,NRDE2,MIR135B,TOM1,STK16,MEF2A,OAZ3,IFNG,MED17,TAB2,MIR34B,GPR37,STX5,DTL,MIR497,RRN3,TRIM24,CARTPT,UBE2N,DIRAS2,CRKL,MSN,SS18,ARRDC3,CDK12,SKP1,PSMC3,ATP5IF1,MIR221,MLLT11,MIR206,CD14,EIF2AK2,RLN2,GNAI2,RIOK2,CREBZF,TNFSF13,AATF,ADRB3,LMO4,ODAM,GRIA1,DERL1,BAD,G0S2,RAB27A,CD34,SMCHD1,KPNA6,LACC1,DVL2,RAMP3,GSK3A,CRY1,STAT1,PKIB,CAND1,TIRAP,LRP6,MORF4L1,MED31,BCL2L1,LMO2,PTEN,JAK2,KHDC1,GRB10,SMAD4,INO80E,TANK,AMELX,RNF128,GABARAP,PRMT5,TNFSF15,NOP53,LMNA,UBE2V1,UBE2V2,CDC7,TMEM106A,GPT,KLK5,CYFIP2,CTNNB1,CTSK,HYAL2,SHLD1,BACH1,WDR77,PIK3R3,NAA16,EIF3D,KARS1,PACSIN3,BOK,EP300,SNX5,RFC3,PDCD10,MIR30B,MIR21,RPS2,HADH,ECD,MIR519D,LILRA2,DHRS4,SYNCRIP,MYBL2,CREBL2,RGCC,UBE2B,DNM2,NOS1AP,MOB3C,SMURF1,MIR548C,EMP2,MIR33B,TCF21,DXO,POU5F1,IREB2,RMND1,FOXD3,PMAIP1,POLR3F,MIR210,CD36,RBBP9,BCL2A1,LYAR,ELK1,MED29,IFNGR1,RXRG,FLOT1,PPARA,PELI1,CXXC1,TRAF7,VEGFC,MIR10A,MTA3,ADRB1,NEUROD2,ZNF263,ENO1,LDLR,HSPD1,AURKAIP1,MIR885,DMAP1,VDAC1,TRIM34,PRL,OTX2,JUNB,HAS3,JUN,PNP,ZFP64,MIR107,ZNF267,UBB,ERP29,RFX5,ABHD6,RSAD2,GTF2F1,FGR,LDB2,POLR3B,RNASEL,MIR185,DUOXA2,UBE3A,IL12B,RNF14,FOXP1,THRAP3,STOML2,BCL7C,MIR657,HSPB8,PLSCR1,PIP4K2C,POMT2,F2,CCR2,MIRLET7C,PSME1,LDB1,ACVR1,TFDP2,BRD3,DDR1,DAP,CGAS,MIR424,OGG1,STRADB,TRIM23,ADNP,TRA2B,FBXW11,H2AX,RFC4,ELOVL6,SH3GLB1,SPHK2,ZNF622,USP16,CXCL10,TNFRSF14,PSMD10,DCUN1D1,ZNF593,HRAS,MIR23A,PYCARD,ZNF304,AGER,PLEKHF1,BATF,LARP4B,GABPA,GTPBP1,CAB39,S100A10,CXCR4,VPS28,EPHA2,INO80C,ZNF770,SSBP4,YTHDF1,BCL7B,HMGB1,MIR495,TRIM6,LY96,RPS3,EEF2,RFC5,NMBR,TRAF2,CX3CR1,MIR145,DBH,MSX1,RAF1,ARMCX3,PTGFR,STN1,ROCK2,MIR640,IL10,YAF2,H2AZ1,DDRGK1,MAP3K11,RBBP7,FGF17,NAA15,LBH,POLDIP3,CRLF3,ADIPOQ,PTGER4,CCDC22,CSNK1A1,CCNA2,RPL23,SFRP4,SP1,CYP7A1,PPARG,MIR106A,RNF187,SESN2,PRKCQ,GPNMB,JUP,ZNHIT1,PGR,FAXDC2,BTG2,TSPO,HECTD1,RAP2A,RNF20,DCP2,MIR193A,COP1,EZH1,RFXAP,IL7,ITK,IL3,UPF3B,EZH2,IER2,CHRNA7,ESR2,YTHDF2,FBXO22,NFYB,NCSTN,IKBKB,IL34,MYRF,TGFB1I1,CHCHD4,EGR1,GAPDH,CNOT7,RAD21,NR4A2,EPO,SLC6A4,GHITM,TFPT,DNAJC2,CDK6,DDIT3,TRIM27,EYA3,TOMM70,PTPN11,HUWE1,ADORA1,ACSS2,FGF22,SIX5,SCAMP5,VGLL2,TSHR,SRSF1,P2RY1,FGFR1,MIR340,HELT,PSENEN,MIR34A,UBP1,ATG101,IL13,MITF,VPS72,ITGA6,KCTD20,IL21,CLEC7A,IDO1,CTSC,SPPL3,TENT5D,CCNY,DIPK2A,TAF7,CXCL8,LITAF,PICALM,MAFG,CDK7,PYM1,HSPE1,MTF1,BAZ1B,AIP,TRIM22,CIRBP,NFE2,TADA3,MIR20A,CCL21,SUMO1,COPS5,SETD3,TRAF3IP3,OAS1,HNRNPC,RNF126,PAGR1,LTA,FOSL2,SHC1,PRKCB,CTBP1,ACTN4,MIR708,MACROH2A1,RIT2,SMAD1,MIR200C,CCT2,MMD,IRF7,TNFSF18,CREBBP,PROX1,JCHAIN,ADTRP,MTDH,ZBTB18,GREM1,PIWIL2,CDH13,SNX33,KLK3,PXYLP1,ABHD14B,DYRK1A,USP13,IRF2,RAP2B,TRIM37,GCLC,NFKBIB,WASL,PTPN22,SOX2,ZBTB38,TF,CPT2,NCK1,IL2RG,IRF6,FGF10,PCNA,SEC22B,IL1A,CHP1,TGFB2,MIR144,RASL11A,SVIP,SRPK2,NOTCH2,KRAS,DPY30,ACTA2,HBEGF,CD4,RPS27L,TNKS2,PSEN1,EGR2,ARL6IP5,ZGLP1,APOBEC3F,IDE,MIR324,SNRNP70,IFT57,SMAD2,MIR342,TAF2,BUD31,SLC38A3,ALKBH5,BRCA1,IFIH1,RBM22,IRF9,ZMPSTE24,RUNX1,MEF2C,CAV3,MSTN,SUPT7L,VGLL4,PIM2,RAB1A,CD28,CBFB,HSP90AB1,AGAP2,TAB1,TNKS,RC3H2,MEAF6,USP8,MEPCE,ACHE,IFNB1,CAV1,WDR45,TNFSF8,SOCS4,SMAD5,HSP90AA1,NFIL3,MED21,INPP5K,HTR2A,DDT,RPS6KA4,OSR2,CDK1,MOV10,APLN,SSBP1,ATP6AP2,SASH3,PDCD5,MIR190B,CD83,PSRC1,CDC20,IFNAR1,DAPK1,MARS1,MIR142,HSPB1,ZER1,MYC,FRMD8,CREB1,IER3,SSBP2,HNRNPA1,WWP2,DLX1,HCRT,MIR106B,CASK,GPSM3,G3BP1,SPON1 |
| 2.656e-10 | -22.05 | E5a (E5a protein) | protein interactions | 1489366 | 273 | 125 | 19454 | 5460 |
ERLIN2,YIPF3,FAF2,PLD3,NDUFA4,TMEM87A,GPAA1,SEC11A,BAG2,SACM1L,PLPP6,RAB18,SLC35A2,RAB5C,RAB32,HAX1,PTK7,GJA1,AGK,ERLIN1,NOTCH2,PGRMC1,SEC62,UBAC2,MMP14,ARMCX3,ATP5PO,VAPB,TMEM115,PIP4P2,FAM8A1,ATP5MK,ATP2C1,TAPBP,RP2,PHB2,SSR3,RER1,RNF5,GPR176,SLC22A17,KDSR,FAS,VMP1,SLC7A11,SCFD1,SEC61B,GGT7,RMDN3,SLC30A7,RETREG3,FZD6,SERINC1,B4GAT1,CHP1,ABHD12,CHCHD3,RAP1A,MTCH2,UBIAD1,YIPF4,TMEM165,SURF4,ATP2B4,ATP5PF,TMX3,BSCL2,SRPRB,TMEM33,GALNT2,RDH11,LPCAT3,FKBP8,CALR,EI24,HM13,ESYT1,SLC2A1,TMEM184C,FITM2,COMT,HACD3,AIFM1,STT3A,ACSL4,COX20,RPS27L,DERL2,ARL6IP5,CAV1,SLC25A12,TMPO,SLC38A2,ATP5PD,SEC22B,RABL3,PSMC4,CNP,SLC35E1,TRAM1,STOM,TM9SF1,FADS2,RETREG2,GLIPR1,MAIP1,MAVS,RTN4,DERL1,CERS2,CLU,DAD1,HMOX2,SAYSD1,ENDOD1,SNX14,GGCX,ATP1A1,CDIPT,SEC61A1,COPE,CTSB,SEC63,VKORC1L1,TECR |
| 2.716e-10 | -22.03 | SRPK1 (SRSF protein kinase 1) | protein interactions | 6732 | 472 | 195 | 19454 | 5460 |
RBMX2,FGFBP1,MACROH2A1,PSPC1,ZNF330,SMURF1,DYRK1A,TFEB,SRPK2,C9orf72,RPF2,ZBTB38,UBE2H,CRHR1,RC3H2,RBM23,DDX46,WDR55,SETD3,GSTP1,KCNAB1,LUC7L3,RPA2,ALYREF,RBM42,DKC1,SURF6,CDC5L,SLAIN2,FZR1,CAND1,RPS16,NKAP,COPS5,API5,MAGEB1,NXT2,SNRNP70,ADPRH,RPL3,DHX9,SRSF12,RPL17,H3C1,KPNA2,FGF12,ARHGAP12,TP53,NUPR1,CBX3,RBM34,DNAJC2,CDC42EP3,CBX5,APEX1,ESR2,MATR3,SNRNP40,SNRPB,MYC,HNRNPC,PHF7,NSA2,CHTOP,RBM27,FTSJ3,DDX5,STK26,EP300,YAF2,SNRPA,PYM1,SRSF2,TRA2B,UFL1,STAU1,SYK,PIH1D1,MAP2K1,CLK4,SRSF1,DUSP6,SNRPD3,LYAR,YWHAG,DDRGK1,IFI16,PTDSS1,UBE2E2,WWP2,DDX1,MAGOH,DRG1,RIMS4,HSPB1,EWSR1,RPL31,PABPC1,RPL28,HNRNPDL,KRAS,PELI1,ISG15,SOX2,ZRANB2,MOB3C,GANAB,GSK3A,PRKRA,PELP1,CCNF,EIF4A3,EIF2AK2,RPL13A,DNAJC8,CIAO1,PPIG,CLK1,SQSTM1,MTDH,RPA3,PPM1G,SIRT7,PRPF4,GABARAP,DGCR8,SMC4,RPL4,FBXW7,CDK7,RBMS2,RPS14,RPLP0,METTL14,KRR1,ZBTB2,TOP1,ZMYND11,NOVA1,NKRF,VTA1,NSG1,THRAP3,TF,MAP2K3,LBR,RPL15,SERPINB10,ILF2,PRM1,SNRPD2,RSRC1,RIOK2,MCM4,NOP16,CUL3,HSP90AA1,SLPI,OCEL1,CCDC86,ALKBH3,MAPKAPK5,MFAP1,ARCN1,USP39,APOBEC3C,VPS18,MAP1LC3A,HP1BP3,MRTO4,PPIA,SRSF10,CEP19,DHX15,HNRNPA1,MAP3K14,AHSA1,DDX23,DROSHA,FAM76B,MRPS11,SRSF8,SRSF7,TRIP4,PPAN,ARGLU1,SRSF4,AHCYL1,SSRP1,FLOT1,GABARAPL1,VDR,RAF1,SKA3,VPS33A |
| 2.731e-10 | -22.02 | CDC5L (cell division cycle 5 like) | protein interactions | 988 | 817 | 310 | 19454 | 5460 |
NIBAN2,CUL3,RFC5,MCM4,CAPG,MCM3,BRCA1,YWHAZ,HSP90AA1,MIR363,RIT1,PELO,UBE2S,SNRPD2,SNRPD1,LRRC1,EIF4A2,RBBP4,TUBB,UMPS,ACTB,LGALS3,MIRLET7D,SNRPB2,EHD1,CDKN1A,USP39,ARCN1,TRUB1,COIL,PSMC1,UNC45A,FOXP2,PSMD3,PRPF19,NDC80,HNRNPA1,TRA2A,UBE2D1,DDX23,DNM2,RPL9,PHB1,XPO5,COPS2,SPTAN1,SNX2,BUD31,DHX15,NUF2,LRWD1,FEN1,ZNF263,TPBG,KHDC4,PPP2R1A,VPS33A,RPN1,CHMP4C,PPFIA2,RPS11,GTPBP1,SNRPE,SCYL2,HSPD1,HNRNPA2B1,ARGLU1,BAG2,SRSF7,RBBP7,DHX16,G3BP1,PPWD1,PSMD12,SRSF4,RFC3,EIF2D,FOXP4,RFC2,CDC16,GMPS,RACGAP1,NONO,AR,STK24,CDC73,CCNF,EIF2AK2,CTNNA1,TUBA1B,EIF4A3,SNX12,DTYMK,TMOD3,VIRMA,SF3A1,WDR83,PSMC4,RBMS2,LMNA,GRM2,HSP90B1,PICALM,LSM2,OXSR1,RPA3,HELLS,MIRLET7I,MYT1L,SMC4,LDOC1,ORC5,LRRC40,KIAA1143,EXOC2,FOXP1,MIR34A,RPL12,MIR106B,SRP14,KRR1,MIR25,SEC23A,TOP1,CDK9,CWC15,ZBTB2,FBP1,CCT5,EEF1A1,DDX39A,CD2BP2,THAP1,ACTR2,ILF2,PPP4C,SRP72,FAF1,EHD4,SEPTIN7,RPL23A,TSSC4,CTNNBL1,ERLEC1,HUWE1,NOC4L,CTNND1,ARF4,MDC1,SMN1,SNRPG,MSH6,LMO2,MYC,HNRNPC,RPL39,PSMD1,SNRPB,CPSF2,CCT2,FTSJ3,KIF3C,H1-1,CMTR1,SF3B4,ANAPC2,MATR3,SNRNP40,DDX39B,RFC4,SNRPA,SF3B1,HSPA8,HDAC5,EP300,DDX5,UFL1,SRSF2,STAU1,EEF1G,SAP18,IFI16,WWP2,MIR143,ZCCHC10,YWHAG,UTP6,DDRGK1,EXOC1,MIR31,POU5F1,CDC23,HSPB1,DRG1,MAGOH,TNIK,GNB3,PRCC,RBM5,SRSF1,EED,MIR214,RPS10,TCP1,SNRPA1,SNRPD3,HSP90AB1,CCT7,TRMT1L,DHX38,SUPT5H,TUBB4B,GLE1,MOB3C,CCT8,RUVBL2,TRIM21,RTCB,PSMA2,HNRNPF,KRAS,RUVBL1,ROCK2,RPS4X,SMARCA5,MORF4L1,RPL7A,CCNB1,SUB1,EXOC5,RC3H2,ELAVL2,CDKN2AIP,UBE2H,RBM7,SF3B6,RPS3,UBN1,FGFBP1,CSNK2B,EIF2S2,PSMC5,SRP54,MACROH2A1,BUB3,IFI6,CDC20,CSTF3,SRPK2,MIR34B,SPTBN1,SUMO1,PPP1R8,CDC42,ZSCAN1,RPA2,HEXIM1,UBE2M,ORC6,BAP1,DDX46,PML,NBN,CWF19L1,RNF113A,ARFIP1,KDM1A,MRPL40,RBM22,MIR107,HSPA5,RBM17,PPM1D,COPS5,CSNK2A1,API5,GAPDH,TUBG1,SMCHD1,SHC1,SNRNP70,UBE2N,RPS16,CAND1,FZR1,MIRLET7G,MIR429,RBM42,TMPO,CDC5L,UBL4A,ACTR1A,ESS2,DDX42,IK,DISC1,NUPR1,PSMC3,SNIP1,ZNF451,RPL3,RAB27A,DHX9,CDC40,NUP107,CSE1L,KPNA2,TGFBR2,HNRNPK,CAPZA1 |
| 2.808e-10 | -21.99 | USP15 (ubiquitin specific peptidase 15) | protein interactions | 9958 | 478 | 197 | 19454 | 5460 |
RPS2,LSM3,USP15,RPL10A,SMAD4,BECN1,SHC1,SNRNP70,COPS5,TPM3,USP2,CAND1,XXYLT1,EEF2KMT,UBE2G2,SELENOF,TAB2,ACVR1,ACTR1A,KBTBD4,IL1R2,TP53,MEPCE,RBCK1,KPNA2,KCNJ2,UBE2H,MRPS16,DNAJC10,LSM6,STN1,UBE2E3,BICD2,SMARCA5,PSMB2,SMURF1,TRIM54,ADRM1,PSMC5,MACROH2A1,UBE2M,HECTD1,GTF3C4,UGP2,KDM1A,DLAT,BAP1,POU5F1,CTNNB1,IFI16,UBE2E2,WWP2,HSP90AB1,CHMP2A,FAM98A,HNRNPL,RNF144B,S100A8,SRSF1,MTA2,MOB3C,RPL18,TUBB4B,TUBA1A,SOX2,EEF2,RPL28,RPS4X,PSMA1,RUVBL1,TRIM21,RUVBL2,TRIM11,RTCB,CTTNBP2,RPL31,PHF7,CKB,PSMD14,PSMD1,COPS7A,HNRNPC,PSMD4,MATR3,SNRNP40,PSMD6,ZMYM2,PRMT5,CSNK1A1,MRPS7,PHB2,HSPA8,MRPL34,BMPR1A,CD40,ID1,PSMD7,BMPR1B,MDM2,RPL35A,PRNP,PSMB1,DFFA,SMAD3,JOSD1,EEF1A1,PSMB9,RPL15,SMAD1,TBK1,RNF20,RIGI,MSH6,MDC1,SMN1,HUWE1,LSM4,SEM1,TRIM63,RPL23A,HAPSTR1,PPP1R12A,GLUL,CDC73,SMAD2,IVNS1ABP,BRAP,RPL26,ATP5F1A,USP14,CTTNBP2NL,DEK,VIRMA,RPL13A,TRIM27,RTRAF,ALB,CCNF,TUBA1B,LMNA,DCTN4,MRPS34,LSM2,FABP4,LSM8,USP8,SMC4,SYVN1,PPIH,PRPF4,MYH2,MED4,TRAF6,PSMD3,PRDX1,STOML2,PPP2R5A,EGLN3,COPS7B,CCAR2,PSMB4,PHB1,RPS11,RNF126,SART3,PPP2R1A,NFE2L1,MCM6,PSMD12,RNF26,LASP1,RBBP7,PRPSAP1,SLC25A5,SENP8,TAFAZZIN,PRPF31,RNF40,MCM4,PKP4,CUL3,RPL19,TAB1,ACTB,TRIM46,RBBP4,RMDN3,RPL37A,AP2M1,RPS9,UBE2S,PSMB7,SKP1,UCHL3,NOP53,TRIM5,BIRC2 |
| 2.815e-10 | -21.99 | FXN (frataxin) | protein interactions | 2395 | 57 | 39 | 19454 | 5460 |
PMPCA,COX5A,AKT1,ISCA2,AK3,MTPN,AK2,RIT1,COX4I1,GATD3,PRNP,TXNDC12,CTSB,PRDX2,TXN,FZR1,CLIC4,JMJD8,SPR,LAP3,GABARAPL2,HADH,GLRX5,IDH2,NUDT19,MSRB3,RNF126,GSTP1,TCOF1,HINT1,PRDX6,PICK1,FBXW7,SRI,GUK1,KRAS,CRYZ,MPST,MX2 |
| 2.819e-10 | -21.99 | PSMB10 (proteasome 20S subunit beta 10) | protein interactions | 5699 | 88 | 53 | 19454 | 5460 |
PSMB5,PSMB4,AIFM1,PSME2,PSMB1,RPL7,STOML2,CBR4,ECD,SFXN1,PSME1,SLC25A5,HSPD1,PSMA5,PSMA1,PSMA2,CAPZA1,HSDL2,NAA35,TOP3B,JUN,UBXN2B,PSMB9,NDUFS3,ACTR2,UQCRC2,ACAT1,PSMD6,ACTB,TENT5C,PSMD4,BCCIP,PSMB6,ATP5F1A,CFL2,POMP,DDX46,RPL27,ZFP64,PSMA3,TMED3,SRSF2,PTN,AZGP1,UNC45A,PSMB3,UQCRC1,NDUFAB1,CD2AP,MED23,ANXA7,SLC25A3,TMOD1 |
| 2.837e-10 | -21.98 | NIPSNAP1 (nipsnap homolog 1) | protein interactions | 8508 | 219 | 105 | 19454 | 5460 |
GRSF1,MOV10,CALR,COX5A,SLC25A46,TMEM70,SSBP1,COX4I1,ATP5PD,MYL12A,ATP5PB,MTCH2,CCT5,MRPL11,MAP1LC3B,NDUFS3,UBE2B,SLC25A24,FASTKD5,NDUFB10,ATP5F1A,TUFM,IVNS1ABP,NRP1,UQCRC2,ENO1,GANAB,PTPMT1,MGST3,RHOJ,CTTNBP2NL,UQCRQ,VIRMA,UQCRC1,GABARAPL2,CDK7,RPA2,COX6C,HSP90B1,SAMM50,MTRES1,CYC1,RPA3,BAP1,SQSTM1,GFM1,PDHB,RGS2,GABARAP,MTRF1,MARCHF5,XPO1,DDRGK1,MRPS26,PHB1,MAP1LC3A,CORO1C,HP1BP3,GATD3,TCP1,RHOH,NDUFS8,EGLN3,NUP35,CCT7,TOP3B,GABARAPL1,EEF2,EZH2,PDHA1,BCL7B,HSPD1,NDUFA4,CCT8,HINT2,COX8A,WDR19,CHCHD2,VDAC1,UBE2A,IMMP2L,AUH,MYC,PMPCA,CUL3,TOMM40,CCT2,FIS1,VDAC2,TACO1,CYB5R3,CCDC90B,SEC61B,ATP5F1B,ACTB,ESR2,TOMM22,ATP5PO,MRPS18A,TBC1D17,NGRN,EXD2,HADHA,HSCB,PHB2 |
| 2.838e-10 | -21.98 | DCUN1D1 (defective in cullin neddylation 1 domain containing 1) | protein interactions | 54165 | 265 | 122 | 19454 | 5460 |
HNRNPF,TFG,COPS4,HNRNPDL,SLC25A5,KLHL23,HNRNPA2B1,RBM3,PABPC1,EWSR1,FAM168A,TUBB4B,SNRPE,RPL18,KLHL12,TRAF2,NUDCD3,COPS7B,RPS10,SNRPD3,KCTD10,HSP90AB1,RPL9,RPLP2,COPS2,DCAF11,DDX1,HNRNPD,YWHAB,PRDX1,CDIP1,TRIM8,RPL6,HNRNPA1,FEM1B,UBE2D3,RNF11,ASB3,HSPA8,DDX5,ARRDC3,PRDX3,DET1,TUBB,SUSD6,KBTBD6,SNRPD1,SNRPD2,BLOC1S5,HSP90AA1,CBR3,COPS7A,CUL2,HNRNPAB,CUL3,RNF40,SOCS5,SNRPB,MCM3,UFD1,GALE,NEDD8,HNRNPK,POLL,RNF20,SNRPG,RPL23A,KLHL15,DHX9,SELENOF,ILF2,KLHL26,STRBP,TP53,EEF1A1,RPL15,CAND1,KCTD3,POLR2I,MRPS23,SYNCRIP,SSBP1,UBE2N,RCHY1,SEC23A,SNRNP70,RPS2,KLHL9,NFKB1,GMPPA,COPS5,ELOC,KLHL22,API5,RPL4,HSPA5,DVL2,RPA3,CSTB,HNRNPH2,LSM12,TNFAIP1,RPA2,ZNF326,DDX4,UBE2F,UBE2M,HNRNPH3,RPLP0,WSB1,TXN,TRIM54,STUB1,RTRAF,DNAJC10,PIP4K2C,SMAD2,NUDT1,TIA1,BRAP,FBXO7,PCBD1 |
| 2.854e-10 | -21.98 | SRSF3 (serine and arginine rich splicing factor 3) | protein interactions | 6428 | 481 | 198 | 19454 | 5460 |
CPSF4,RBMS2,GRM2,METTL14,MRPS34,LMNA,RPL26L1,ZNF574,SIRT7,PPIH,CLK1,HMGB1,MRPL17,AATF,UTP23,MRPL20,BRIX1,PPP1CC,USP14,CASC3,PPIG,EIF4A3,CCNF,SFXN2,PRKRA,GSK3A,RPP25L,NDN,COPE,MAGOHB,MRPL11,TMEM126A,MRPL49,MRPL51,ILF2,NKRF,ZC3H11A,VRK1,THRAP3,HUWE1,SMN1,MRPS18C,RPS13,GRSF1,MOV10,HDAC6,CRBN,KRR1,PRR3,MRPL50,MRPL24,MRPS23,PGRMC1,PPP1CB,USP39,FAM3C,MRPL57,CUL3,CUL2,MRPL16,PRPF31,ZCRB1,NOA1,FYTTD1,ZNF22,TSN,ACTB,USP5,B3GNT2,TOMM7,EZH2,TMEM14B,MTMR2,HNRNPA2B1,MRPS11,SRSF8,SRSF7,PCNA,TRIM37,TNF,G3BP1,UBE2A,SRSF4,MRPS35,PSMD3,TRA2A,HNRNPA1,MRPL18,ZCCHC9,MRPS26,PHB1,RPL9,FOLR1,BUD31,DHX15,NUP35,SRSF10,MRPL10,WWP1,ZNF326,SDCBP,NLE1,RNF113A,MRPL41,RBM22,MRPL40,RPS15,HSPA5,EIF4E,RPL7A,TIA1,RC3H2,EIF3G,UBE2H,RBM7,ELAVL2,PHAX,MRPS28,ADRM1,MRPS21,EIF4H,SRPK2,DYRK1A,RPP25,MRPL47,ESS2,IK,MRPL52,DHX9,MRPS18B,HNRNPK,CDC40,MRPS33,RPL17,CAPZA1,MEPCE,SRSF12,CD81,COPS5,SNRNP70,TSNAX,MRPS9,SYNCRIP,CAND1,DKC1,MBD5,MALSU1,ZC3H14,MRPS18A,TRMT112,PIH1D1,EIF4B,NGRN,HSPA8,SF3B1,STAU1,UFL1,TIMM17A,TRA2B,TMEM177,HNRNPA0,SRSF2,MRPS7,SAP18,HNRNPC,MYC,BTF3,MRPS25,FTSJ3,ATG3,CIRBP,MCAT,ICAM1,COP1,MRPL13,SF3B4,SMU1,SNRNP40,MATR3,ISG15,CCT8,PABPC1,RBM3,EWSR1,HNRNPF,KRAS,HNRNPDL,WWP2,DDRGK1,MRPL9,YWHAG,HSPB1,YWHAB,MAGOH,POU5F1,SRSF1,EED,HNRNPL |
| 2.877e-10 | -21.97 | B3GAT1 (beta-1,3-glucuronyltransferase 1) | protein interactions | 27087 | 377 | 162 | 19454 | 5460 |
TFRC,TMEM165,SNAP29,CCDC47,PREB,LBR,UBIAD1,SLC29A1,RHBDD3,SLC6A8,FKBP8,STX8,RAB1A,NSDHL,DLG1,STX18,YIF1A,SNAP23,POR,SLC2A1,SMIM12,ESYT1,OSBPL8,AGPAT1,EI24,TMEM199,DHRS7,HM13,DNAJC1,ARL6IP5,LMAN1,STX6,SLC38A2,TMPO,CAV1,PTPN1,SRPRA,EHBP1,CAMLG,SLC39A10,RB1,CDCA3,AP1AR,GOLGA5,STOM,PICALM,USE1,SSR1,TMX4,SLC12A2,LEMD3,RABL3,UBA52,SEC22B,ARHGAP1,YKT6,SLC7A1,TMEM209,NLGN1,TEX264,ITM2B,SPCS2,MTDH,ARFIP1,SQSTM1,ARFGAP3,EPHA2,LRP6,ATP1A1,KCNQ5,DEPDC1B,HMOX2,SLC6A6,GORASP2,SNX3,YES1,SEC63,VAMP3,NECTIN2,ATL1,SRP54,STX10,STIM1,VAMP2,RPN1,STX12,PLD3,HGS,STBD1,MACO1,NETO2,ARFGEF1,FAF2,TMEM59,YIPF3,TNPO2,IFNGR1,EMC8,SLC20A2,RETREG1,TMEM87A,EFNB1,CDK5RAP3,SLC20A1,PTDSS1,PPFIBP1,DDRGK1,SNX2,VAMP7,GJA1,NEO1,SGMS1,CYB5A,STX5,TMEM115,VAPB,SDC2,CMTM7,ARCN1,FDFT1,GINM1,GJC1,NOTCH2,PGRMC1,BET1,GOSR2,TOR1AIP2,SEC62,RAB6A,GOSR1,RER1,STX7,DPH6,ATP2C1,TXNL1,BET1L,STK26,SLC35F2,GCC1,LMNB1,MYO6,SLC38A1,SCFD1,VMP1,ZMPSTE24,FAM219A,TMEM38B,VEZT,RAB11A,PSMD1,SLC30A5,MB21D2,STAT1,CHCHD3,NLGN2,ATP6AP2,ARF1,FAM91A1,FZD6,SLC30A7,FAM83B,SEC61B |
| 2.936e-10 | -21.95 | Inpp5b (inositol polyphosphate-5-phosphatase B) | protein interactions | 16330 | 37 | 29 | 19454 | 5460 |
TRMT112,RAB6B,PRDX3,RAB6A,UBL4A,RANBP1,RAB8B,PSMA1,PSMA2,HMGB1,RAB5A,RAB1A,PFDN6,EIF3G,NME2,PSMD7,SNRNP70,GLO1,PSMD3,PSMB2,RAB5C,SMURF1,RAB1B,OCRL,PSMB1,RAB31,PSMB5,PSMA6,PSMB4 |
| 2.943e-10 | -21.95 | CCT4 (chaperonin containing TCP1 subunit 4) | protein interactions | 10575 | 487 | 200 | 19454 | 5460 |
DUSP6,CCT7,HSP90AB1,DYNC1I2,TCP1,SUMO2,DDRGK1,ACTR3B,CTNNB1,XPO1,PFDN5,MAPK4,AGR2,DCAF5,ACTR1B,CDK5,CCT8,RBM3,HNRNPDL,PFDN1,KRAS,TUBA1A,ISG15,SOX2,MOB3C,RAB4A,HDAC11,TUBB4B,SMU1,ESR2,PPP5C,BTF3,KLHDC8A,PSMA4,MYC,APOBEC3B,COP1,ICAM1,PSMD14,CCT2,DDX5,HDAC5,HSPA8,STAU1,UFL1,UBL3,FBXO42,MTMR6,PIH1D1,PACRG,EIF4B,PPT1,TRAPPC3,CDC5L,TMPO,FZR1,GAPDH,COPS5,CD81,B9D1,TUBG1,POC1B,MAP1B,METTL18,DUSP19,STRADB,MEPCE,TOLLIP,DYNC1I1,KDM4B,ACTR1A,TP53,RPSA,TFCP2,PSMA6,SMURF1,CDC20,BUB3,MAP3K3,KCTD9,PTPN11,SLC25A1,FGFR1OP2,AKT1,UBE2H,TRIM23,RC3H2,RAP2C,HCFC2,NLE1,BAP1,BCL6,WDR55,HDAC3,CFTR,CCNH,UBE2M,HEXIM1,SSR1,SAMM50,WRAP53,TRIM68,RPA2,IGBP1,PPP2CB,PHB1,FOLR1,CETN2,EGLN3,DCAF11,AHSA1,SKIC8,HECTD3,HNRNPA2B1,SAR1B,PCGF6,FLOT1,RBBP7,WDR37,RAF1,POLR2C,CHMP4C,NME1,NGB,EZH2,SNRPD1,GNB1,ACTB,PRDX2,CUL3,RIT1,ILK,PFDN4,PFDN2,BRCA1,DCAF4,RHOB,PSMA3,CRY1,TXNL1,FBXW4,THOC3,COIL,PPP2R2C,UCHL3,PPP1CB,ALKBH3,ACTL6A,WDR77,SLC25A3,EEF1AKMT3,ACTA2,ARL10,G6PD,CDK9,SUV39H1,HDAC6,FNDC11,FGR,HAPSTR1,FAF1,RIGI,FBXO25,HSPE1,DNAAF10,HUWE1,CCT5,RNF181,PPP4C,MMACHC,ACTR2,PTEN,PPM1M,ZBTB18,GANAB,TUBA1B,SMAP2,CCNF,PDCD5,VIRMA,ARMC6,NDN,AR,USP14,FBXO7,ATP5F1A,CDC73,STK24,SQSTM1,MTDH,FLCN,PRPF4,RPA3,IRF7,CCND1,WDR5B,WDR83,PDCL,METTL14,CDK1 |
| 2.976e-10 | -21.94 | response to organic cyclic compound | biological process | GO:0014070 | 843 | 331 | 18204 | 5365 |
GNG2,HSPA8,DAG1,ADORA1,SRC,GHR,CALY,SST,UGT1A1,TRIP4,TMEM38B,COMT,PTGES3,P2RY1,MGARP,KCNJ11,INSIG2,LEP,PIK3CG,TFPI,KLF4,FIBIN,PHB2,TOMM70,HOMER1,HTR5A,GNAI3,MDM2,TAF7,TIAM1,PIK3CA,F7,SOD2,TACR3,DDX5,P2RY12,HPCA,ITGA6,PGR,JUP,PQBP1,CDKN1B,CDO1,NQO1,MLC1,NR2E1,RAN,TSPO,BTG2,CCNA2,CYP7A1,LIPA,OPRK1,SP1,SLC16A1,ALPL,MECP2,CYP27B1,EGR1,FGF23,MYRF,PTGDS,SLC6A4,EPO,TICAM1,ABHD2,SLC22A6,EZH2,CHRNB2,NCSTN,ESR2,CD40,CDK5,RALB,CLDN4,GNB1,TOP2B,GABRB3,CXCR4,FBP1,HDAC6,NKX3-1,H2AZ1,MUL1,ROCK2,IL10,PTGFR,SRSF2,TNF,ADIPOQ,SHMT1,RBBP7,SLC7A11,STC1,ACTB,BIRC2,PHB1,PPP1R1B,PDE12,ATP1A1,PAQR8,EIF4A3,RAP1A,HNRNPD,UBE2L3,CRHBP,CYP1B1,FKBP4,TLR2,G6PD,HBE1,CD38,NEFL,CFTR,THBD,CDK4,ACAT1,P2RY11,VPS54,GRM2,WBP2,PDE2A,CDKN1A,HSP90B1,FOS,DUSP6,FOLR1,NHERF1,CXCL10,CITED1,OGG1,GNA11,TYMS,MRGPRX1,CGAS,OPRL1,NFKB1,GPR83,KCNJ8,DRD1,EIF2S1,PTGER1,ERRFI1,CDK1,KLF9,HTR2A,INPP5K,REN,FOXP3,ATP5F1A,CCL3,CD83,YWHAH,SLC1A3,PELI1,PPARA,FLOT1,OPRM1,RXRG,IRF3,HSP90AA1,SMAD5,MMP14,UBE3A,RNF14,DDX1,MIR185,TLR3,GNRH1,FOXP1,DNTT,CRYAB,SOCS2,PADI2,GNAO1,BGLAP,GNAQ,IFNA10,IL6,IGF1R,CREB1,SFRP1,PTGER2,EIF4E,FBXO32,BRCA1,MTAP,TAF2,TACR1,MIR342,SMAD2,MYD88,RWDD1,PLCB1,GABRB2,IFNK,PCK2,TLR9,IFIH1,ARL6IP5,MIR96,IFNA2,MIR21,PSMB2,SELENON,MSX2,CLDN1,ATP1A3,AQP3,EPHX1,USP8,WNT10B,TXNIP,RBFOX2,GPBAR1,MAVS,HTR1A,ADCY3,RIGI,SIN3A,CAV1,IFNB1,ELK1,SMYD3,ADSS2,EFNA5,MSTN,RUVBL2,CIB2,MEF2C,CD36,GUCD1,CDKN2D,FKBP1B,UCN,PMAIP1,IL1B,SPP1,TGFB3,AIFM1,GSTM2,DHX9,SLC6A1,WNT7A,FAM107A,P2RY4,GCLC,MIR182,ELAVL4,DRD3,HCFC2,ITGA2,FKRP,HAND2,CST11,ADTRP,MBD3,SULT1A3,DDIT4,FOLR2,IFNA13,NSG1,CALR,TGFB2,IL1A,RFTN2,SLC6A3,UCP2,NFKBIA,OXTR,GPX1,KCNMB1,BAK1,GABRG2,VDR,MAP1B,NPR2,SLC1A2,PCNA,AANAT,CTSK,GH1,CTNNB1,FGF10,GJB2,SLC1A1,SOX9,CBL,IL22,CTNNA1,CCR5,GRIA1,TADA3,RPL27,GPX4,MSN,CNR1,SLC8A1,ATP1A2,CYP1A1,AR,PAK2,TRIM63,IL2,TGFBR2,BECN1,KDM1A,LRP6,GAD2,STAT1,TLR7,STXBP1,PPP5C,JAK2,BCL2L1,OR51E2,SMAD1,IGFBP4,ATF1,RAP1B,IDH1,TWIST2,ADCY2,HDAC5,PRKCE,PRKCB,EGLN2,GSK3A,GNA14,FOSL2,RAMP3 |
| 2.985e-10 | -21.93 | STAT1 (signal transducer and activator of transcription 1) | protein interactions | 6772 | 315 | 140 | 19454 | 5460 |
ATF3,TRIM21,JAK1,MYO1B,TRIM11,G3BP1,KIT,LASP1,NAA15,RAF1,VDR,ACTN4,ISG15,JUN,IFNGR1,EZH2,AQP3,CCR1,OTULIN,IGBP1,SNX2,SNX1,SPTAN1,HSP90AB1,UBXN6,VPS26A,CIAO3,WWP2,ATG7,XPO1,CTNNB1,CASP12,FKBP4,AHSA1,CXCR4,PRKD3,FOS,HSPA8,YAF2,EP300,HSCB,STAU1,RNF11,ITGAV,IL2RG,ATP6V1C1,SYK,SHMT1,USP39,PAK2,CSNK1A1,IRF2,NFKBIA,STAT1,STAT2,BPIFB3,JAK2,ESR2,MYC,CREBBP,USP13,LMO2,IRF1,SOCS5,MCM3,GGH,MYO6,BRCA1,CCR5,EIF1AD,HUWE1,CTNNBL1,CAMK2G,TGFBR2,CSE1L,KPNA2,HADH,MAP1LC3B,PIK3CA,PSMC3,APEH,EEF1AKMT3,TES,RB1,SPPL3,CAND1,PRNP,CDK9,IRF9,KARS1,USP2,COPS5,SLITRK5,POR,KPNA1,TSNAX,TEX264,RPA3,SEPTIN6,PML,PRKCB,SQSTM1,MAVS,GTF2I,HDAC3,FBXW7,PIAS1,ATG16L1,SPTBN1,CDC42,CD2AP,FTH1,H2BC11,RPA2,HSP90B1,CCNF,CTTN,EIF2AK2,TNFRSF1B,GSK3A,MSN,UBE2I,STAT5A,TMOD3,NR1H2,PRKCE,SMURF1,RPP25,IDE,SRC,DUSP3,NMI,TNFAIP3,AKT1,PTPN11,IL2RB,FOXA3,KPNA6,PKNOX1,ATP1A1 |
| 3.011e-10 | -21.92 | NSD2 (nuclear receptor binding SET domain protein 2) | protein interactions | 7468 | 257 | 119 | 19454 | 5460 |
KDM2A,NCK1,RPL6,IFI16,HMGA1,PRDX1,BAZ1B,CTNNB1,TRIR,LYAR,RPS10,HNRNPL,PPIA,ZNF593,RPL8,SIN3A,CCDC71,HP1BP3,TOP3B,FEN1,SERPINA3,RPL29,RPS27A,SRSF4,RPL28,RPL31,PCNA,FTSJ3,BRCA1,H1-1,RPS26,ZNF668,SNRNP40,TAGLN2,RPL19,ESR2,APEX1,FAU,RPS9,GTF2F2,RPL37A,ADNP,LARP4B,H1-5,WDR77,STAU1,NOP53,ZNF692,AZGP1,COIL,LCN1,RPL24,TIAM1,BRD3,RPS2,HP,TOP1,RPS16,PLEKHF2,SURF6,ZBTB2,TMPO,RPL32,ALYREF,KRR1,SRP14,NECAP1,LLPH,CBX3,CHAMP1,SERPINA1,TP53,RPL15,THRAP3,TF,HNRNPK,H3C1,MDC1,RPL17,SMN1,TCOF1,MAP1B,RPL3,RPL23A,MECP2,DTL,RPL7A,SUB1,SMARCA5,AR,RPL26,VIRMA,SCML2,ZBTB33,ENO1,ZNF330,CREB1,PTEN,PRKRA,FGFBP1,RBMX2,HBB,LMNA,TOX4,RPLP0,SAP30BP,RPL4,PFKFB2,HMGB1,NUCKS1,GTF2I,NPM3,DGCR8,KDM1A,UTP23,CLU,NHP2,SIRT7,DDX46 |
| 3.039e-10 | -21.91 | regulation of endothelial cell migration | biological process | GO:0010594 | 236 | 115 | 18204 | 5365 |
MIR10B,MIR424,MIR16-1,HDAC5,NRP1,FGF1,TMSB4X,MIR29C,ATP2B4,MIR200C,STAT5A,MIR492,MIR497,CSNK2B,MIR221,MIRLET7B,FOXC2,GADD45A,MIR206,MIR320A,MIR20A,MET,PRCP,PRKCA,ATP5F1B,GLUL,MIR640,CALR,ROCK2,MAP2K3,MIR24-1,MIR101-1,PDCD10,TNF,SPRED1,MIR505,STC1,RHOB,GFUS,MIR23A,PLG,MIR361,PROX1,MIR152,FBXW7,SEMA5A,STARD13,CD40,AKT1,EPHA2,WNT7A,FGF16,MIR495,MIR205,HMGB1,MIR150,NUS1,MEF2C,MIR29A,MIR129-1,VEGFA,MIR210,MECP2,MIR204,MIR137,NFE2L2,MIR146A,MIR30A,FGFBP1,MIR21,PTN,PPARG,MIR503,MIR212,CXCL13,MIR149,SP1,MIR296,RGCC,RHOJ,MIR31,AAMP,JUP,MIR342,MIR193A,EMP2,GAB1,NR2E1,HSPB1,MIR143,MIR15A,MIR135B,SYNJ2BP,MAP3K3,MIR126,SVBP,MIR200A,MIR188,FOXP1,MIR133B,VEGFC,KRIT1,PIK3CG,MIR939,EMC10,KLF4,MIR10A,ANGPT1,MIR885,FUT1,AKT3,MIR132,ATP5F1A,FGFR1,VASH1 |
| 3.071e-10 | -21.90 | RPL23 (ribosomal protein L23) | protein interactions | 9349 | 496 | 203 | 19454 | 5460 |
RPS26,COP1,ATG3,BTF3,RPL39,PSMD1,MYC,RPL10,ESR2,TAX1BP1,PRMT5,NFKBIA,CMTR1,CNDP2,PIH1D1,MRPL12,RPL27A,UFL1,THBS3,HSPA8,RPS28,SNRPA,AGR2,CTNNB1,DDRGK1,WWP2,RPL6,RAMP3,RPS10,EED,RPS23,RPL18,RAB4A,TUBB4B,EEF2,RPS7,ISG15,PAEP,RPS4X,RPL28,KRAS,RPL31,S100B,UBE2H,ATP1A1,RC3H2,SPOP,HFE,RPS17,RPL7A,BCCIP,ROMO1,CDC20,SMURF1,RPL10L,RPS3,CSNK1G3,HEXIM1,RPA2,CFTR,CDC42,CLU,HSPA5,RPS15,RNF113A,BAP1,RPL27,TMOD2,RPL10A,RPS2,FAM187B,SNRNP70,RPL24,TUBG1,API5,COPS5,CSNK2A1,ENY2,RPS27L,CAND1,RPS16,FZR1,RPL32,PSMC3,CAPN2,NHERF1,DNAJC2,TFCP2,RPSA,TP53,UBL4A,RPL17,MEPCE,DYNC1I1,RPL3,PSME1,MAP1B,NTRK3,RPS5,BRCA1,DCAF4,CUL3,DBH,CUL2,ACO2,MAD2L2,RPL19,TUBB,RPL35,MRPL23,SEC61B,RPS9,RPL37A,EMC9,MED23,KCTD12,DET1,NOTCH2,TOR1AIP2,WDR77,G3BP2,EXD2,RPL23,AHSA1,CDH13,MAP3K14,EIF3D,PDIA3,RPL7,RPLP1,RPLP2,PHB1,RPL8,KLHL7,RPL9,FOLR1,RPS11,CHMP4C,EZH2,RPL29,B3GNT2,RAD21,UBE2A,RPS27A,TRIM37,RBBP7,EMC8,G3BP1,TNF,RPS24,MRPS11,SLC25A5,TRIP4,TUFM,USP14,PPP1CC,AR,RPL26,FBXO7,EMILIN1,VIRMA,RPL22,RPL13A,NDN,COPE,PTEN,RPS20,RPS12,DNASE1L1,PPM1M,LURAP1,CCNF,RPLP0,RPL26L1,METTL14,CCL3,CDK7,ATG16L1,RPS14,BRIX1,PIAS1,RPL4,RPA3,DVL2,FGR,MSMB,GTF2E1,HDAC6,MDM2,CDK9,RPL35A,RCHY1,ACTA2,RPL12,EFNA3,ITGB8,ILF2,RPL15,FBP1,RPS13,VRK1,HUWE1,RPL23A |
| 3.097e-10 | -21.90 | Influenza Infection | REACTOME pathways | R-HSA-168254 | 157 | 87 | 10285 | 3229 |
POLR2C,RPL35A,RPL28,HSP90AA1,RPL23A,NUP42,RPL6,RPS20,RPS16,RPS24,RPLP1,RPS29,RPL13A,RPL10L,RPS13,RPS27A,RPS5,RPL15,RPS28,NUP62,RPL22,RPS3,RPL17,RPL10,RPL35,RPL18,RPL9,ISG15,POLR2G,RPL4,RPL27,GTF2F2,RPS12,RPS23,RPL37A,RPL7,UBA52,KPNA1,RPL10A,RPL29,RPS7,RPL26,POLR2B,RPL39,RPL24,XPO1,RPL7A,NUP107,RPS14,GTF2F1,POLR2I,RPSA,EIF2AK2,RAN,NUP37,GRSF1,RPL32,FAU,RPL3,CALR,KPNA2,RPS4X,RPLP0,RPL27A,NUP35,RPLP2,RPL8,RPS26,NUP153,RPS17,CPSF4,RPL26L1,RPL19,NUP50,DNAJC3,RPL12,RPL31,RPS2,POLR2F,RPS11,RPS9,POLR2D,POLR2L,RPS15,RPL23,RPS27L,RPS10 |
| 3.102e-10 | -21.89 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | REACTOME pathways | R-HSA-176814 | 77 | 51 | 10285 | 3229 |
PSMD7,PSME1,CDK1,PSMD10,UBB,CDC26,UBA52,PSMD14,PSMC4,PSMB5,PSMA3,NEK2,PSMB1,CDC20,PSMB7,CDC16,PSMD3,PSMB3,BUB3,PSMB6,PSMA2,PSMA5,PSMB10,PSMC5,PSMB11,PSMA4,ANAPC4,PTTG1,SEM1,PSMB9,CDC23,PSMB4,ANAPC15,ANAPC2,PSMD6,PSME2,UBE2D1,CCNA2,ANAPC11,PSMD4,RPS27A,PSMA1,PSMC3,PSMC1,CCNB1,PSMD12,ANAPC16,PSMA6,MAD2L1,PSMB2,PSMD1 |
| 3.111e-10 | -21.89 | regulation of vasculature development | biological process | GO:1901342 | 364 | 163 | 18204 | 5365 |
ADM2,MIR193A,RUNX1,EMP2,GAB1,NR2E1,MIR30E,JAK1,RGCC,BRCA1,RHOJ,MIR31,GPNMB,JUP,PPARG,STIM1,MIR503,NIBAN2,MIR212,MIR375,PGK1,CXCL13,SP1,MIR146A,MIR30A,MIR30B,MIR21,TSPAN18,MIR137,NFE2L2,HSPB6,MECP2,CMA1,MIRLET7G,VEGFA,MIR210,CHRNA7,GTF2I,MIR29A,MIR99B,VASH1,PRL,TNFSF12,MIR1224,MIR885,FUT1,MIR34C,AKT3,MIR132,KLF4,MIR10A,CCL11,VEGFC,APLNR,FASLG,LEP,KRIT1,MIR939,PIK3CG,EMC10,IL17F,CXCL8,MIR223,MIR34B,EFNA3,MIR106B,FKBPL,TLR3,MIR185,IL6,SYNJ2BP,SFRP1,MIR126,MIR1-1,ROCK1,HSPB1,AGO1,MIR143,MIR15A,CAMP,BTG1,MIR34A,MIR20A,GHRL,PROK1,MIR17,MIR214,MIR377,PRKCA,XBP1,SLC12A2,MIR222,RLN2,CYP1B1,AGGF1,GADD45A,MIR130A,MIR221,TGFBR2,MIRLET7B,CCR2,FOXC2,NINJ1,MIR492,MIR378A,MIR29C,CHI3L1,ATP2B4,CXCL10,SMAD1,NRP1,MIR125A,FGF1,JMJD8,PML,STAT1,PRKCB,MIR16-1,TERT,HGS,CD34,MIR424,DDAH1,FGF16,MIR495,MIR205,CD40,MINAR1,IL1B,CXCL12,EPHA2,CXCR4,ITGB8,KLK3,SEMA5A,EMILIN1,RHOB,GREM1,MTDH,MIR23A,MIR361,ZNF304,PDCD10,TNF,SPRED1,MIR505,CCR3,IL10,MIR640,ROCK2,IL1A,MIR1298,MIR24-1,MIR101-1,TGFB2,MIR145,GLUL,CCM2,CX3CR1,CTNNB1,TNFAIP3,CCL24,ADAMTS1 |
| 3.163e-10 | -21.87 | NBR1 (NBR1 autophagy cargo receptor) | protein interactions | 4077 | 366 | 158 | 19454 | 5460 |
PLD3,CTNNA2,PLS3,JUN,GABARAPL1,ISG15,CSNK1E,PSMD12,SAR1B,RAB18,RFC2,G3BP1,PSMA1,S100A10,TRIM37,DNAJB4,TRIM21,RPS24,MRPS11,ZYX,CYP2C9,HAX1,RB1CC1,IKBKB,SYT4,DDX23,FKBP4,CRTAP,YWHAG,ATG7,ATG9A,GSTM3,RAB5C,MARCHF5,ZCCHC10,DIRAS3,GLRX,CACYBP,HSP90AB1,PAIP1,RAB1B,HNRNPL,SPTAN1,MAP1LC3A,NRSN1,EED,ATP6V1A,KRT8,SPRED2,PSME2,WDR6,SDC4,FEZ1,NUFIP2,TBC1D13,VAPB,SEC62,MTMR6,PXMP2,PSMC1,FTL,UBE2D3,FXR2,ATP5IF1,HSPA8,DDX5,TMEM160,SNRPA,EXD2,COP1,CKB,CCT2,ATG3,BTF3,CDC123,PSMA4,SSH3,TAX1BP1,TUBB,NDFIP1,LMBR1L,ATXN1L,GNAI3,RP9,TFRC,TMEM31,ACTR2,LBR,MAP1LC3B,TBK1,RRM1,TP53,RPSA,CCT5,YTHDF2,VTA1,ARF4,KPNA2,TOLLIP,MRPS18B,RAB13,RPL3,LTBR,SLC25A10,ZNF787,TCOF1,OSBPL8,SMCHD1,GAPDH,LYPLAL1,SLC25A12,G6PD,CAV1,PREP,CEBPG,NAA30,METAP1,AIFM1,AIP,GSTP1,JUP,IGFBP3,UQCRC1,GABARAPL2,ATG16L1,SYNGR2,EDDM3B,SUMO1,SPR,GABARAP,AATF,MRPL41,USP8,SQSTM1,MAVS,RPA3,CORO6,CSTB,IRF3,EXOSC1,PPIG,MAPRE1,CFL1,GMPS,CARS1,RETSAT,RPL7A,MORF4L1,VIRMA,JUNB,RAB14,MAP3K3,GSK3A,TMEM74,ACAT1,OPTN,PELP1,UQCRC2 |
| 3.177e-10 | -21.87 | response to endogenous stimulus | biological process | GO:0009719 | 1402 | 517 | 18204 | 5365 |
PTGFR,XCL1,ROCK2,IL10,RAF1,MIR1298,FGF17,RBBP7,TNF,ADIPOQ,SHMT1,ACTB,TWSG1,FGF3,CYP11B2,PPP1R1B,PHB1,PAQR8,MIR145,CX3CR1,MSX1,ATP1A1,AVPR1B,CDK5,HFE,CLDN4,EPHA2,CXCL12,MME,FGF7,GABRB3,TOP2B,CHRDL1,MIR23A,HRAS,AGER,FBP1,CXCR4,ITGB8,CAB39,MIR98,CDKN1A,HSP90B1,NDN,CYC1,VAMP2,FOLR1,INPPL1,CITED1,RB1,TYMS,SLC22A12,CYP11B1,GPR83,RAB31,TMEM107,PTGER1,EID2,CASP4,ACVR1,CASTOR2,GJA1,CFTR,NEFL,CSNK2B,FOXC2,FUT8,ARF6,FKBP8,HADHA,TP53,GNAI3,MDM2,CXCL8,TAC1,TAF7,TNFSF10,POR,EHD1,DDX5,LEPR,GPR173,SOST,HPCA,HSPA8,GHR,PTPN1,FGF22,COMT,TIMP4,UGT1A1,TRIP4,TMEM38B,TSHR,FGFR1,P2RY1,DDIT3,TLR4,PTPN11,PAX9,ZBED3,TOMM70,KLF4,TRIM44,MKKS,CYP27B1,EGR1,SLC6A4,PTGDS,EPO,NR4A2,EZH2,IER2,EIF2B2,NCSTN,ESR2,CHMP5,PGR,SESN2,JUP,CDO1,CDKN1B,GAB1,KLHL22,BTG2,TSPO,NQO1,SFRP4,RPL23,MIR30A,PTGER4,CCNA2,MIR212,PPARG,SP1,CXCL13,TGFB2,MAP2K3,DUSP3,ACTA2,NOTCH2,EIF2B3,PCNA,AANAT,GABRG2,GJB2,SESN3,FGF10,SPP1,GSTM2,PDE8A,COL3A1,SOX2,PTPN22,SPINT2,GCLC,ADRB2,SULT1A3,CST11,ADTRP,CDH13,CCR7,FOLR2,DDIT4,STAT6,GAD2,CAV2,KDM1A,CTSB,MIR339,LCN8,EIF4EBP2,SMAD1,OR51E2,RGMB,RAP1B,TWIST2,IDH1,CRHR1,REG1A,SHC1,GNA14,HDAC5,FOSL2,CBL,STAT2,SOX9,CTNNA1,TADA3,CPEB1,CCL21,MIR20A,GHRL,CHST11,RAB13,ATP1A2,FMOD,SNAI2,BECN1,PELP1,DLX1,DEFB124,SOS2,EPHA4,MIR200A,CCL5,MIR106B,KCNC1,GSTM3,SOCS2,MIR142,MARS1,HSPB1,CREB1,IGF1R,FLCN,SFRP1,FERMT2,FBXO32,CSNK1E,PTGER2,TIMP3,MYC,KLF9,HTR2A,INPP5K,REN,ATP5F1A,PDCD5,ID1,YWHAH,OPRM1,HSP90AA1,USP15,SMAD5,FURIN,USP8,TAB1,HTR1A,RBFOX2,CAV1,MSTN,CAV3,STAMBPL1,EFNA5,MEF2C,ZYX,BRCA1,SMAD2,MYD88,TACR1,SOCS5,ZMPSTE24,HTRA2,GABRB2,CD81,GPR22,EGR2,MIR146A,PSEN1,DTYMK,CLDN1,IDE,MIR149,ATP1A3,DUSP22,SMAD3,SLC2A1,LHB,STC1,YES1,RAP1A,EIF4A3,TMEM108,UBE2L3,COL1A2,CRHBP,HNRNPD,WNT2,RAB14,ACVR1B,GNB1,FGF16,SYK,ADIPOR1,STK11,HDAC6,FCGR2B,NOG,NKX3-1,WBP2,PDE2A,PML,SOSTDC1,CCL2,FOS,DUSP6,HCLS1,NHERF1,NPPC,BMPR1B,GNA11,KCNJ8,DRD1,NFKB1,CYP1B1,FKBP4,NDP,TLR2,RARRES2,MIR183,CD38,CD2AP,STAT5A,FEZ1,ACAT1,FRS3,VPS54,CCL19,P2RY11,RAB35,NTF4,ICAM1,F7,PIK3CA,MIR143,CAMP,P2RY12,STK16,PDCD4,ROCK1,GNG2,ADRA1A,SRC,CALY,DAG1,SST,CSH1,MGARP,EXT1,PTGES3,FASLG,LEP,INSIG2,PIK3CG,REG1B,MIR140,BACE1,PHB2,FIBIN,TFPI,ALPL,MECP2,FGF23,BMPR1A,AKR1C1,NFE2L2,TICAM1,SMAD9,AKR1C2,ABHD2,SRSF4,LPXN,TIMP1,VEGFA,BMPR2,AMIGO1,PIK3R2,ACAP2,NR2E1,PIK3R1,RAN,EIF2B5,MIR493,RXFP2,SHOC2,NTRK2,FLRT2,OPRK1,STMN2,NTRK3,NSG1,CALR,PIK3R3,UCP2,EP300,IGF1,RETN,GPX1,OXTR,GPT,MT3,SLC1A2,HYAL2,CTSK,AGTRAP,NPR2,MAP1B,SLC1A1,GH1,CTNNB1,TGFB3,NDNF,AIFM1,TBC1D4,AKT1,WNT7A,FAM107A,VSTM2A,ITGB5,ELAVL4,P2RY4,KBTBD2,FKRP,GRB10,SMAD4,SELENOS,DRD3,ITGA2,TLR6,LRP6,PCSK9,NRP1,STAT1,FGF1,NR1H2,JAK2,BCL2L1,ACACA,UGCG,RGMA,GSK3A,PRKCE,EGLN2,CRY1,RAMP3,IL22,PID1,FLRT3,GRIA1,XBP1,RPL27,CRKL,NCOA5,AR,TRIM24,SLC8A1,TGFBR2,PAK2,MIR130A,TRIM63,CCND1,FCER1G,MMP14,RNF14,UBE3A,TMEM100,ACVR1C,YWHAG,SLC2A8,GNRH1,PADI2,ADIPOR2,GNAO1,GNAQ,BGLAP,MIR107,CSK,NDST1,AHCYL1,IL6,MIR379,EIF4E,ERRFI1,CA2,LDLR,JUN,PRL,AKT2,SLC1A3,VEGFC,UPRT,RXRG,PPARA,EEF1A1,EDNRA,WNT10B,DSTYK,TXNIP,SERPINB9,PAX6,SIN3A,ELK1,SMYD3,ARPC3,LDOC1,NUS1,RERG,CIB2,CD36,UCN,JAK1,SMURF1,GNRHR2,RWDD1,TNFRSF1B,PCK2,TLR9,PLCB1,HADH,CD9,MIR30B,MIR21,FGFBP1,MSX2,SELENON,EHD4 |
| 3.221e-10 | -21.86 | ubiquitin-like protein ligase binding | molecular function | GO:0044389 | 322 | 149 | 18094 | 5411 |
TRIM37,CKB,FATE1,CACYBP,UBE2D1,RNF8,CUL3,PSMD1,RTN4,ANKRA2,YWHAZ,EIF4E2,RNF40,PML,HDAC6,TUBB,SLC25A5,CXCR4,UBE2B,CLU,PTPN22,MAP1LC3A,HSP90AA1,STX8,SMAD1,SHPRH,SPOP,UBE2N,WRAP53,TSG101,BOK,CDKN1A,STAT1,XRCC5,UBASH3B,STUB1,HSPA8,HSPD1,CASC3,FZD4,NFE2L2,JAK1,FAF2,UBE2D3,GABARAPL1,PAX6,SPOPL,USP2,RHOBTB3,FBXO7,RALA,ANAPC2,TXNIP,WBP1L,TANK,TCP1,FAF1,DIO2,HSPA5,TRIB1,TOLLIP,ERLIN2,GABARAPL2,TNFRSF14,SUMO2,FHIT,RALB,DBT,RNF20,RB1,SQSTM1,UBE2K,MUL1,BCL10,HM13,TUBA1B,PRR5L,DLG3,SMAD2,CACUL1,NFKBIA,BRCA1,CCT2,RPA2,CDKN1B,RPL23,ISG15,MAGEC2,GPR37,CD40,USP13,TMBIM6,FBXW7,HSP90AB1,SUMO3,GABARAP,LTBR,RRAGA,DDRGK1,CCNB1,PSMA3,UBB,MAP1LC3B,UBE2W,CAMLG,TRAF2,FZD6,TNFRSF1B,UBE2A,CALR,ACVR1B,UBA52,TRIP4,UQCRC1,SUMO1,CDK5RAP3,STAT2,JUN,ABCB1,H2BC9,DERL1,POU5F1,RNF34,EGR2,RIGI,SMAD3,MDM2,DET1,ERLIN1,SMG5,BECN1,RPS27A,NDUFS2,NAE1,PIAS1,TP53,HAPSTR1,NEDD8,TRAF1,CUL2,PRKACB,PRDX6,HGS,UBE2L3,BAG2,JKAMP,CTNNB1,SMAD5,PACRG |
| 3.316e-10 | -21.83 | PSMC2 (proteasome 26S subunit, ATPase 2) | protein interactions | 5701 | 352 | 153 | 19454 | 5460 |
PSMA6,STUB1,CCNF,PSMC5,CHMP5,ADRM1,LDHA,VIRMA,CEP85,PSMB2,KPNA6,AR,USP14,TXNIP,MRPS16,UBE2H,ATP1A1,CDC73,PDCD4,SIRT7,BAP1,DDX46,SOD1,RPA3,DERL1,SQSTM1,DESI1,HSPA5,ATG4C,PSMC4,ATG16L1,UBLCP1,CFTR,PAAF1,NEK2,METTL14,GRM2,RPA2,ACACA,UBE2M,HEXIM1,GTF2B,AIFM1,SEC23A,PSMB1,PRNP,FZR1,CDC5L,MYL12A,TMPO,TPM3,COPS5,PPM1D,PSMD7,CCDC92,USP15,PSME1,FAF1,ABCE1,PSMA5,HUWE1,CNOT7,SEM1,FKBP8,PSEN1,MEPCE,VTA1,INSIG2,CLEC2B,PSMB9,TMEM31,RAD23B,ZFAND2A,PSMC3,TAF2,LMBR1L,GTF2F1,ANAPC2,PRMT5,SNRPD2,PSMD6,RPL35,TUBB,PSMD4,NCKAP1,ESR2,PSMB6,PSMA4,LDHB,CUL3,MYC,ALDH1L1,BAG3,PSMD1,PSMD14,FTSJ3,BRCA1,LAMTOR1,CCT2,POMP,RIT1,HERC3,PSMA3,YAF2,EP300,AKAP1,TXNL1,TRIM5,UFL1,PSMC1,DDI1,POLA2,PSMB3,CDKN1A,BORCS6,PSMB7,PSMB5,PPP2CB,PSMB4,PSME2,RPLP2,CCAR2,HSP90AB1,EGLN3,VPS26A,NDC80,RAB5C,PSMD3,DDRGK1,XPO1,ATG7,YWHAH,PSMD10,TRAF6,LRRC57,CCT8,UBE3A,G3BP1,PSMA1,KRAS,PSMA2,RAD21,RPS27A,PSMD12,B3GNT2,TNPO2,PPP2R1A,GFPT1,SOX2,RPN1,EZH2,MOB3C,POLR2C |
| 3.319e-10 | -21.83 | DDX18 (DEAD-box helicase 18) | protein interactions | 8886 | 321 | 142 | 19454 | 5460 |
RPS10,NOP58,LYAR,DHX15,RPL9,RPL8,PHB1,EED,DDX23,AGR2,RPL23,IFI16,WWP2,DDRGK1,MAP3K14,KRAS,G3BP1,GNL1,RPL28,RPS4X,RPL31,PPAN,FGF3,COX8A,RPS24,UBE3A,RPL18,RAF1,RPL29,SOX2,RPS7,SNRNP40,RPL35,RPL7L1,BTG3,RPL10,RPL19,SURF2,RPS9,DCAF4,RHOB,LMNB1,CRMP1,NSA2,CDKL2,H1-1,RIT1,POLR1B,MYC,RAB11A,CUL3,BTF3,ZNF668,HSCB,UFL1,STAU1,COIL,G3BP2,HSPA8,SF3B1,DDX5,EP300,APOBEC3C,PPARG,MAP2K1,MTF1,SYK,EHHADH,BET1,CAND1,DKC1,ZBTB2,SURF6,KLF9,KRR1,ARL4D,RAC2,PWP2,MPHOSPH10,CHCHD1,SNRNP70,H2AC4,RPS2,RPL10A,BRD3,GRSF1,COPS5,HDAC6,H3C1,TGFBR2,VRK1,RIGI,RPL17,TCOF1,ABCE1,RPL23A,RPL3,ILF2,NUPR1,TP53,AURKAIP1,RHOJ,RPL13A,SMURF1,BCCIP,SRPK2,CCNF,ZNF330,EIF2AK2,FGFBP1,PRKRA,RC3H2,ZBTB38,MAPRE1,UBE2H,SMARCA5,RPF2,RPL7A,NPM3,WDR3,DGCR8,RPL4,PIAS1,BRIX1,UTP23,AATF,RPL27,RPA3,SIRT7,PRKCB,RAB9A,RNF113A,LMNA,RPA2,HEXIM1,RPLP0,MACROH2A2,RPS14,AGO1,CDC42,POLR1D,KLF12 |
| 3.354e-10 | -21.82 | cytoplasmic vesicle | cellular component | GO:0031410 | 2521 | 866 | 19108 | 5553 |
FTL,AGTRAP,NRSN2,ZNRF1,DDIT3,UBXN6,HSP90B1,CLEC18A,NSG1,OPRM1,GCHFR,CAMK2G,PHB1,GPC1,RHOBTB1,TEX264,RAB14,PSEN1,LAMTOR3,MMP14,GABARAPL2,STX7,ABHD6,PSMA5,CD9,GH1,HGS,B4GALT1,GRIA2,CYSTM1,CD46,CD164,FGD2,ERP29,BET1L,GRIA1,MT3,RAB33B,SGIP1,TUBG1,SLC30A7,GOSR2,VEGFA,COTL1,CDC42EP4,AKT2,SFTPA1,LACRT,TP53INP2,RETN,SLC35G2,EEF2,CST3,ANXA7,PTPN1,SNX5,KDELR1,EHD3,SLC48A1,RAB40AL,HCRT,CARTPT,PRDX4,IL2RB,RAB3B,DISC1,RAB33A,IL2RG,PROS1,SEC22B,CD274,SH3GLB1,AP1S2,PSMD14,WDR44,LDLR,TLR2,PRSS37,SELL,TRAF3IP2,TUBA1A,RAP1A,SYPL1,SERPINA1,NPPC,ICA1,SYNGR2,CYRIB,FCHO2,BLOC1S3,BOK,VTI1B,CLRN1,RAB18,NCDN,ROGDI,ARMC8,VDAC2,ITM2B,CHP1,EPHA4,LRAT,CYB5R3,GABRA2,USE1,LHFPL2,CTTN,ACAP2,SCFD1,GRAP2,PRL,TM9SF4,LYZL6,YKT6,GHRL,RAP2C,ACTN4,CLU,ENPP4,VAMP1,TMEM108,CD59,AP5M1,SYP,JUP,FGR,WASL,AGA,FOLR1,HP,PITHD1,SYNDIG1,ORMDL3,MDM2,NIPA2,MLC1,DSN1,ADRB2,ERG28,FCGR2A,PDLIM4,PTP4A3,DNAJC5,HSPA5,AP1G2,ABCC5,UBA52,CPTP,VPS54,TASL,RARRES2,SLC6A4,DYNLL1,FURIN,ACTR1B,HSP90AB1,TREML1,CAND1,RHOU,EHD4,SDCBP,XRCC5,ATP6V1G2,RAB9B,GABRA1,ARF6,SLPI,PLEKHF2,CHIC2,TRAPPC2L,RP2,BRI3,CLCN6,DNM2,KIT,NRBF2,RAB31,TOR4A,RGS19,SYNGR1,SLC35F1,HPS6,GOSR1,TMEM30A,GZMK,TMEM198,MYD88,VPS18,GDI2,PLCB2,KLK9,RAB1B,ATP8A1,RNF133,KCNJ11,KLHL12,IL12B,HEXA,CPNE1,ATG16L1,PLA2G4B,PCSK9,SNX11,AGAP2,STXBP1,RAB3A,GJA1,MMP9,ATG7,CD2AP,ZYX,SEPTIN6,RACGAP1,NRSN1,RAB13,SCAMP2,RAB39B,PYGB,TBC1D24,CFAP119,PLEKHF1,RAB8B,TIRAP,TOLLIP,MAP2K1,AFTPH,LILRA3,SNAP29,CHGA,DNASE1L1,MAGED2,RNF167,DKK1,OVGP1,TMED3,IL1B,SLC11A2,CTNNA1,CTSD,CDC42EP2,ALB,MARCHF3,BCL2L1,VTA1,ADRB1,CCT8,MTMR2,SCG2,ARHGAP21,TEX261,IL15,RNASE6,CTSA,SPACDR,PDE6D,EMP2,DPP4,IL15RA,TRAPPC13,STX6,NECAP1,UBB,IFNAR1,TAB2,TMEM106B,TM9SF1,DEGS1,ATP6V0B,GABRB3,SQSTM1,RAP2B,ABHD17A,SYBU,RPS27A,YWHAZ,CX3CR1,STX16,CD4,CHID1,WDR83,TMEM59,GPR15,PSMC5,GABBR1,ITGAV,EHBP1,CYB561,HFE,HMOX2,DPEP3,COPE,SLC2A1,STMN2,RNF128,CD1C,ATP6V1E2,NEU1,MREG,CXCR1,LDLRAD4,TNIK,SIAH2,TLR4,ATP6V1A,CHMP1B,SPTAN1,OLR1,TRAPPC14,PLG,SLC38A9,PDAP1,PPFIA3,CRHBP,B2M,AP3S2,CTTNBP2,ADD2,TLR8,NECAP2,CD14,PGA4,SIGMAR1,PSENEN,ANKRD50,SNAP25,WDR11,RAB1A,VIPAS39,DLG4,MBL2,VAC14,MYO1B,SYT2,HSP90AA1,IDH1,TBC1D17,TRAPPC1,CLBA1,FIG4,CHMP1A,SELENOP,RHCG,PGM1,MYO6,WNT7A,OCRL,CMA1,TBC1D5,CTSB,GGH,PDIA6,SRGN,CD1E,CD1D,PTP4A2,LYZ,RABAC1,CAMKV,PLAC8,LYZL4,CCDC22,CAPN1,OCIAD2,OPRL1,PSMB7,AQP11,VPS28,PRDX1,STARD4,CAPG,SYK,SFTPD,SCYL2,PHETA2,TOM1L1,CD47,CLIP3,AP2S1,SUV39H1,SLC4A8,SFTPC,ABCB9,VWF,RAN,HCLS1,TNFRSF1B,SPRED2,ATP6V1D,PDE4B,FCAR,TRIM3,STX11,FASLG,CXCR4,TESK1,AP2A1,RNASEK,SEC13,NTF4,TMEM165,CSH1,TBC1D10C,RAB27A,HILPDA,KCNH1,ENPEP,TAX1BP1,ATP1A1,TRAK2,TLR3,GANAB,PSMD7,LAMTOR1,SEC23A,PADI2,SLC39A13,ATP6V1G1,SLC1A1,TICAM1,IL12A,TIMP3,CD1A,CHMP2B,SSPN,STX17,GPR89A,PLD3,AP1AR,STX8,KLK3,JAK2,SRC,MMD,STX12,CNIH1,TLR9,NPTX1,LGI3,AVL9,LAPTM4A,GNPNAT1,SCAMP5,CCR5,PSMD12,APH1A,RALA,SERPINA5,TMEM123,CSTB,SYN3,PGRMC1,RAB5C,CDIP1,RAB9A,STX1A,RAB35,SERPINB10,YPEL5,DYNC1I1,AVPR1B,MCOLN1,NTRK2,CHMP2A,SLC31A1,ATP6V1C1,CDKN1B,PSMB1,GTPBP2,SEMA4C,VPS26A,LAMP2,SNX24,BST2,HEXB,FAF2,AQP4,SCG3,MIF,TMEM168,SNX14,PICALM,LAMP5,TRAPPC3,RND2,CALY,TMEM33,TAPBP,ATP1A2,PRDX6,SH3BP4,HYAL2,ENTPD4,NCSTN,SLC66A2,RAB5A,SNX20,NPC1L1,VAMP5,CXCL1,KLK6,TRIM27,MTM1,TMED4,COMMD9,AMELX,PSMC3,ARCN1,RNF11,EHD1,SLC1A3,CCT2,RUSC2,SLC15A2,EXOC3,VPS26B,LRP6,PYCARD,ACTR2,SVOP,DVL2,HSD17B6,TMEM190,TICAM2,STAMBPL1,TRIM21,PDIA3,HDAC6,TRAF6,FZD4,NDUFC2,RPN1,TGFB3,GLIPR1,TP53INP1,SRP14,PAFAH1B2,DNAJC3,DBH,LPAR2,SERPINA3,PACSIN3,PICK1,COPS4,LGALS8,OCEL1,ILF2,FGL2,GOLGA5,DERL1,USP8,CAV2,PRSS12,CD36,SLC12A2,SNX10,CHMP4C,TFRC,VAMP2,STAMBP,ANXA4,ITGB5,AQP2,TRAF7,HERC3,HBA1,KLK5,SNX22,REEP6,CAB39,REP15,PARM1,OPRK1,SRI,SNX2,TRAPPC6B,MRC1,TCP1,MOXD1,CLVS1,SERPINB6,TRIM36,IGF1,TMEM179B,CPE,OLA1,LGALS3,BPIFA2,PLA2G5,GABARAPL1,EEF1A1,SYNGR3,NPC2,RAB6B,RAB11A,TUBB,GABARAP,RAB11B,PSMA2,STX10,CACNG3,NPY,RNF148,STX5,PSMD1,CD58,RAB32,HSPD1,RAB3D,RAB6A,CIDEB,SNX17,GABRG2,DERL2,TMT1A,STK26,LY96,PRDX3,APEH,VAMP7,NCALD,CALML5,OR51E2,ARPC2,FABP5,PCYOX1L,GNAI2,JAK1,ADAMTS1,PRRT1,CYB561D2,FAM91A1,GCA,LMBRD1,ABHD2,ATP1B3,HEBP2,IZUMO1,TNFAIP6,VPS16,ASTN1,RAB37,PNP,RAP1B,STBD1,RAB29,TBC1D25,HAS3,PSEN2,GAD2,FCER1G,USP14,BACE1,PML,IRAK4,TMUB1,GSTP1,LAMTOR2,TLR7,USP6NL,SNAP91,COPS5,SLC2A3,ATP6V0E1,CDC42,VEZT,UBE2D3,STOM,TMEM199,TRAPPC10,TMEM127,VAMP8,CAV1,SERPINI1,SERPINB1,LITAF,SAYSD1,APOC2,TUBB4B,TMED9,TMED1,BET1,TNFAIP1,YIF1A,CPLX3,TLR6,GPNMB,INPP4A,SOD1,STK16,SLC18B1,RAB2A,VPS33A,BECN1,MAP1LC3B,BLOC1S5,RHOG,TSSK1B,CORO1C,TMED5,NME1,HUWE1,PPIB,BORCS5,SNX3,LPAR1,VPS4B,PDYN,ACKR3,TMBIM1,NME2,TF,CD63,AZIN2,CLCA1,TYROBP,BICD2,EXOC8,FTH1,CMTM6,VAMP3,TLR1,CLIC4,PIP4P2,TMEM95,ACTL9,PRCP,TNF,LEPROTL1,SLC17A5,TIMP1,SST,CLVS2,CALU,SAR1B,CHMP5,CTLA4,S100A11,AP5S1,CNP,HBB,PPT1,SNX33,COMMD3,KDELR2,FZD6,TGFB2,LMAN1,YWHAB,HTR2A,SV2B,CTSK,TRAPPC4,YIPF5,RAB23,DENND6B,ZDHHC17,PSMD6,TBC1D16,RAP2A,RAB22A,ARRDC3,SCG5,RAB3C,SVIP,RNASET2,GABRB2,CALR,YIPF3,TSPAN15,CFTR,CD1B,APPBP2,HAX1,PIP4P1,SLC30A5,HBEGF,TMSB4X,FAM3C,RHOB,NRP1,SLC32A1,CAMP,DIO3,SYNRG,HMGB1,SPRED1,SYT4,PSMD3,NUDT1,ROCK1,CYB5R1,S100A8,TAB1,PAK2,CRHR1,PPIA,DIPK2A,TPT1,SNX1,TMX3,SNX12,CHI3L1,RAB4A,UBAP1,PCSK2,SURF4,MAP1LC3A,CD3G,MME,TOM1L2,AP1M1,TMED7,C9orf72,NDFIP1,CNIH4,STARD3NL,SNX18,TMEM45B,VPS26C,SIGLEC5,FLOT1,PGAM1,TSG101,TOM1,SLA2,RAC2,SYNPR,PLEKHJ1,CTSC,FGFR1,FCHSD2,ZMPSTE24,GOLGA7,COPZ2,PLEKHO2,IFT172,PPFIA2,FCGR1A,NFKB1,LAMP3,HSPA8,PATE4,ESD,CSNK2B,SYNGR4,AP2M1,SPPL3,TTR,VPS4A,ARHGAP1,VPS39,NF2,ATP6AP2,OPTN,ATG9A,SNAP23,SLC2A8,FCMR,VEGFC,IRF7,TMEM74,SPG21,IQSEC1,CDC37L1,GDE1,SNAPIN |
| 3.376e-10 | -21.81 | regulation of cellular localization | biological process | GO:0060341 | 983 | 378 | 18204 | 5365 |
ZDHHC8,ABHD17A,RANGRF,ORMDL3,NSFL1C,STX1A,GOLPH3L,CDK5,RAB11B,RHOU,EPHA2,HFE,VPS28,CTDSPL2,OAZ2,TRIM46,PKIA,CCT8,HRAS,ADIPOQ,TNF,DDRGK1,ACTB,NDUFAF2,ROCK2,ERLEC1,RAB11A,TRIM6,MIR17,CFTR,LMAN1,EDEM2,F2,ARF6,CTSD,UFM1,VAMP2,SH3GLB1,CDK9,NETO2,RAC2,ARHGAP1,HSPA8,PTPN1,HUWE1,PTPN11,TOMM70,TLR4,LRRC8A,MDM2,TMEM30A,VCPIP1,SUMO3,TNFAIP6,HPCA,IL13,OAZ1,UBE2D3,EHD1,VPS4A,NCBP2,MLC1,SUFU,RHOG,JUP,SESN2,CLSTN3,SCFD1,PPARG,UFL1,SLC16A1,CD247,EPO,LGALS3,RNF139,CHCHD4,WASL,GAS8,VAMP8,DHX9,SNX33,ADTRP,REEP6,CREBBP,C9orf72,FRRS1L,SVIP,OSBP,CHP1,TGFB2,IL1A,RAB29,OTUD7B,JAGN1,TRIM8,GHRL,TRIM22,NDFIP1,BAG3,CTNNA1,FIS1,DLG1,PICALM,RER1,EDEM1,FKBP1A,MMD,CCT2,OR51E2,ATP2B4,TTC8,CHRM1,KDM1A,OS9,MACROH2A1,TRIM29,MAP2K1,PRKCB,PPP1CC,CHGA,SUMO1,PDCD5,RAB9A,CDK1,INPP5K,IL12A,HSP90AA1,STX8,BTF3,PARD6A,SNAP25,CDK5R1,GDI2,OPRM1,CCL5,KCNB1,WWP2,UBAC2,THOC2,TRIM68,ARFIP1,IER3,SFRP1,FERMT2,CSNK1E,CRYAB,PPIA,CDC42,RBM22,MRLN,HTRA2,PKIG,SNX3,PSEN1,MIR146A,LILRB4,CD81,ATP2C1,TYROBP,CAV1,ACHE,MEPCE,USP8,MAVS,HSP90AB1,SWAP70,CNPY4,FKBP1B,AP2M1,EFNA5,CAV3,VTI1B,RINT1,TMBIM6,RAB14,DERL2,PRR5L,HDAC6,NKX3-1,FBXW7,TRIM5,STK11,APBB3,SLC7A11,SPTBN1,ISCU,XPO1,SMAD3,GLUL,RAP1A,CCN3,RHBDD3,UBE2L3,TFRC,SELENOK,PLN,STX6,CD2AP,CD38,LAMTOR1,SLC12A2,TLR2,NLGN2,PICK1,AKAP8L,PIAS1,YIPF5,C2CD2L,TMEM97,VIP,FEZ1,TMEM59,HCLS1,SYBU,PML,NUP62,DNAJC1,CACNB4,CHRM3,TERT,TESK1,SRI,GNA11,TMEM231,UBXN2B,P3H1,NRDE2,MTMR2,KCNJ11,PPID,WRAP53,UQCC2,ANGPT1,DAG1,STAC3,SRC,CALY,SQSTM1,LEP,TRIM21,CD200,TM9SF4,STX18,PIK3CA,TIAM1,DYNLL1,PGRMC1,IFNG,NEO1,OAZ3,STX10,PIK3R2,RAN,PIK3R1,YWHAZ,CPLX1,BORCS5,TOMM7,CCT5,TCP1,CAMK1,STOM,MECP2,UBL5,VRK1,LYPLA1,NF2,BNIP3L,UBE2G2,PPP3CA,WNT7A,LMNA,DPH3,IL1B,TGFB3,AKT1,AGR2,DRD3,GPC1,LZTFL1,PFKFB2,B9D1,CCT7,ENY2,PDCD10,UCP2,IGF1,DKC1,EP300,TAX1BP3,SIRT7,BAK1,TXN,MAP1B,TCAF2,HYAL2,CTNNB1,SLC1A1,INPP5E,SNX12,RIOK2,ANP32B,PID1,ATP5IF1,NUP153,MSN,CNR1,CRKL,CARTPT,AR,RIC3,JAK2,TSG101,BCL2L1,PCSK9,NR1H2,STX7,PRKCE,GSK3A,CDK5RAP3,RAMP3,LCP1,PARL,BAD,AKT2,PPP1R12A,TRIM34,DMAP1,UHMK1,CLIP3,HAX1,BVES,PRNP,VEGFC,GPC4,TMBIM1,GPM6B,MIR223,ACSL4,ACVR1C,RAB23,MMP14,IL12B,DPP10,MX2,MIR185,EFCAB7,IL6,CSK,RSAD2,ERP29,BAX,MIEF1,GNAO1,PTP4A3,HDAC3,RTN4,GNAZ,PCK2,PLCB1,JAK1,MIR148A,NGDN,PPP2R5A,DNAJB6,SYT4,SFN,HADH,SIN3A,IFI27,EDNRA,SAR1B,CD36,BAP1,SNAPIN,MIR210,TP53INP2,NUS1 |
| 3.638e-10 | -21.73 | KTN1 (kinectin 1) | protein interactions | 3895 | 299 | 134 | 19454 | 5460 |
UBE2H,MAPRE1,MFSD14B,EIF3G,VAMP5,ATF4,CIAO1,CSK,SEC63,ADRM1,SGTA,UBE2I,EIF2S2,METAP2,CCNF,PSPC1,CDR2,SSR1,STOM,WWP1,METTL14,ZCCHC17,RPA2,PAAF1,ST7,CDC42,PDCD1LG2,TPT1,CAPN1,ATG16L1,FBXW7,RPL4,LPAR1,PDHB,NPM3,DERL1,RAB9A,RTN4,RPA3,PSMD7,NEUROD6,LAMP3,SLC25A46,ENY2,DPP4,AKAP17A,LMAN1,TMPO,RBM42,STX6,CGAS,DNAJC1,RPS16,RAC2,HSD17B11,CDR2L,PTPN1,SRP72,CAPZA2,TFRC,FKBP8,RIGI,RAB3B,EMC2,CLEC7A,TMEM179B,HSP90AA1,FIS1,RAB11A,MYC,RPL19,APEX1,ATP6AP2,SYNE4,FBXO22,RPL35,DYNLL1,SEC61B,CD3G,RETREG3,LMBR1L,ARMCX3,EMC9,BORCS6,EHD1,OTULINL,RND2,SEC62,G3BP2,PXMP2,ARMCX2,TACR3,STX7,EEF1G,STAU1,SYNPR,RAB5A,AKAP1,HSPA8,DRG1,RB1CC1,AGR2,RHOG,WWP2,RAB5C,FRA10AC1,IFI16,LAMP2,HSP90AB1,TMEM237,NUF2,RHOH,GJA1,PHB1,MOB3C,RND3,RAB4A,STIM1,RPN1,DNAJC25,SNAPIN,YIPF3,HEXA,E2F4,TOP3B,RAF1,B3GNT2,PSMA1,KRAS,EMC8,RTCB,TMEM147,TMT1A,CYP2C9 |
| 3.682e-10 | -21.72 | membrane-enclosed lumen | cellular component | GO:0031974 | 6022 | 1931 | 19108 | 5553 |
H2BC12,ACOX1,CCDC92,IVNS1ABP,PTPN1,ZBTB25,DHX16,PCGF3,MRPL13,RPS16,NUPR1,EZH1,TRAF2,HINFP,ATP5PB,MARS1,SDC4,NME4,DDX39A,HEXIM2,SNAPC5,MFAP3L,CSNK1E,SUGP1,NT5C3A,USP3,POLDIP2,PSMA3,NOSIP,CITED1,PROS1,IL2RG,RAD1,SAP18,MIDEAS,CGGBP1,USP13,ECD,SERPINA1,MRPS21,AIFM1,CYRIB,DNLZ,PIP4K2C,POLR3F,NUP107,CEBPE,RNF20,BAALC,UBN1,ACTL6A,VTI1B,ARMC8,IDH3A,PRKAB1,CBFB,HSD17B8,FANCG,CYB5R3,MRPL22,UBE2B,VDAC2,ENC1,SMDT1,SDHB,ZNF655,HSP90B1,STK4,LSM6,ZNF174,FAU,RFXAP,ATP5F1B,PSEN1,MMP14,NOL7,SF3A1,PPP3CA,PSMA5,KCTD10,CCNY,GH1,SNRNP40,HGS,NFE2L1,SETD9,FASTKD5,MALSU1,RNF34,ANAPC16,ERP29,CDC5L,NOB1,PNO1,RAB33B,S100B,MACROH2A2,OS9,CDK20,IGF2BP1,RPF2,TOP2B,MRM2,RBM12,S100PBP,DNAJC19,TXNRD3,BCKDK,CKS1B,EAF2,WDR55,NUP42,NRDE2,KIF2A,CST3,RETN,AKT2,GTF2E2,ZMAT5,YAF2,WEE2,WBP11,KIT,RPP21,RP2,UBE2E3,ACOT6,SNAI2,SERPINB9,CTNNBIP1,PRSS23,TP53TG5,CDK5,SERPINC1,HSPB6,MAGOH,PLSCR1,TEX12,EHHADH,RPL7L1,RBM34,CDK5RAP3,UFD1,NR2E1,MCPH1,TIA1,SENP5,IL12B,GNPAT,UGDH,IDH2,PCSK9,CPNE1,EGLN2,GID8,DUSP3,PARP11,MSX1,HEXA,FEN1,POLR3GL,NUCKS1,AK3,RBBP4,GRSF1,KHDC4,AGAP2,SMYD3,PAK5,EXOSC1,MRPS9,RBM17,CD2AP,ATG7,POLA2,GJA1,AR,H2AX,EWSR1,SPATS2L,MCM4,IRF4,SNIP1,HEY2,RBFOX2,RPL7A,GRAP2,DR1,VRK1,REXO2,POU1F1,MECP2,TIMMDC1,SPR,WRAP53,CLU,ACTN4,HNRNPA2B1,HCFC1R1,DNTT,AGA,BIRC5,SMCHD1,MRPL17,JUP,SF3B5,POLR2C,DSN1,RPS3,NDUFB8,DCTPP1,OLFM2,CFDP1,VPS54,SDHAF1,UBA52,ABCC5,SUPT4H1,PSMB3,TRMT6,CFL1,CMC4,TASL,SMNDC1,ERCC3,CEP19,ACTR1B,ADRA1A,MPG,ZBTB6,ZMAT2,NMRAL1,HSPE1,CCDC86,DDX5,NFE2,NUF2,EDEM2,HS3ST1,NMI,RSRC1,PPP1R10,SNRNP70,UBE2V1,GABPA,CRYM,PNMA3,POLE3,RPL12,CLPB,DNAJB9,CD4,CMPK1,NCOA5,PSMC5,CDC73,TERT,FAM20C,COPE,PLEKHA8,VPS72,COPS2,SIVA1,DCAF5,STK24,TNIK,NDN,XAF1,ATP6V1A,CDK8,NAB1,ZNF397,LIG3,PDAP1,PLG,AKT1,H1-10,NSMCE3,PIWIL4,PRKCA,NUDT2,ZCCHC17,SETD7,BRCA1,ABHD5,ZCRB1,SPRY1,ZCCHC9,DAG1,MATR3,CTDSP1,TYMS,CHMP1A,DROSHA,SOX2,DCUN1D3,CMAS,CHCHD4,ZNF593,NUDT16,NIBAN2,PCGF6,CENPW,MORF4L1,CSTA,PYGB,PIH1D1,BRIX1,TOLLIP,RPS23,MTDH,ELK3,LANCL2,SAMHD1,RPL18,GADD45A,CREBZF,BPNT2,CRABP2,S100A10,MAGED2,NDUFB4,CDKN1A,DNASE1L1,RRAGA,FKRP,P3H1,MEAF6,RORB,MPHOSPH10,HOXC4,NBN,BCL2L1,AGO1,CHRDL1,SMARCA5,SCG2,IL15,GRAP,EEF1AKMT3,BMPR2,DCK,MRPS16,POGK,BCL9,PAK6,PLPPR1,TFCP2,GTF2B,TAF9,PRKX,STX6,PHF21A,SURF6,PPM1G,TRIM68,PNMA2,AKIP1,SQSTM1,ZBTB14,PDE2A,YWHAZ,NFYB,MYG1,STAT2,SEC13,METTL22,PAAF1,HDAC3,RPS10,RAB27A,RFC5,GMNN,RCL1,PDIA2,SDF2L1,PSMD7,PRR13,MAD2L1,KDM4B,ARGLU1,XBP1,JAK2,DTYMK,NSA2,WDR12,PPP5C,ABHD14B,PLD3,EXOSC8,DDX23,LCMT1,NDC80,SRC,STX12,ACOT8,STN1,SRSF1,INTS12,DHRS4,XPO1,LYPLA1,RBBP8,LRWD1,PSMD12,FOXA3,IGFBP3,NKAP,MRPL24,ARFGEF1,SNRPD3,BRAP,GPX1,CRADD,VIRMA,DAPK3,POLL,STOML2,PFKFB2,PRKCB,CRKL,HNRNPK,STAT6,PPID,GGH,WDR77,RPL27A,ALYREF,CD1E,EXOSC4,TRIM45,SRGN,TCEAL1,RPS12,TRMT5,ARL4A,CREBBP,ID1,FBXL3,TRIM37,MRPL10,PRM1,CENPL,HP1BP3,CRTAP,RPS24,ANP32B,TRIM5,CASK,RPAP2,PHYKPL,PLAC8,ACOT13,PSMB7,CDK2AP2,SLC35F6,CSTF2T,CAPN1,ORC6,SMAD5,VCPIP1,TNFAIP8L3,COPS7B,KDM1A,HADHA,DMTF1,RARS1,FAM118B,NTMT1,DFFA,POLB,MTA2,SUV39H1,HECTD1,SATB1,VWF,NFKBIA,SFTPC,LAMB2,MTRES1,GTF2A2,CHRAC1,AGPAT5,HNRNPF,ANAPC4,FASLG,MRPL50,ANAPC2,METTL21A,ZNF322,GNAI3,SIN3A,LMNA,DPH3,DVL2,ACTR2,COX19,RNF40,IP6K1,ANKRD10,PRELP,MINDY3,EDEM3,MSL2,SP4,IMP3,HSBP1,CDK12,DEDD,DPEP1,LUM,TRIM21,NR1I2,MTG1,PHF7,FAM107A,MZT2B,MED21,TCEA2,ADH1B,HDAC6,MRPS28,DNAJC3,TP53INP1,SERPINA3,MRPS25,LIAS,COPS4,MPST,TRMT112,MTA3,KPNA2,IER2,CPSF1,GINS3,NUP35,PTHLH,LHB,LSM3,PSME1,SNRNP48,MRFAP1,STAMBP,SUPT3H,NAIF1,SNAPC1,ZHX3,VDR,LLPH,RPL19,CHCHD1,SDC2,GEMIN7,SHPRH,EEF1E1,CDKN1B,G2E3,NDUFAB1,MEF2B,LAMP2,CIRBP,HINT1,GTPBP2,ZNF501,ORC5,CBLL1,PRELID1,UBLCP1,SYNCRIP,DCAF4,BAZ1B,SHMT1,PRMT2,MAP3K14,ZBED4,PARP2,UPRT,PRRC2A,RRN3,PPP1CB,PRDX6,MGAT4A,ACAA2,MECR,SF3B6,SOD3,SNX20,FKBP4,TOPORS,GINS4,DEFB1,PC,SRSF12,PRKAG1,KLK6,OGN,CXCL1,LYPLA2,GABPB1,RNF208,COMMD9,PPIL3,SNRPD1,MAGOHB,TRMT10B,ZNF330,MRPL18,ACO2,BAHD1,APEH,TOR1B,CENPP,TUFM,TFIP11,CALML5,MFAP1,PCLAF,RPL8,GNAI2,CFAP20,PLCB1,PCYOX1L,ELK1,NOC4L,RASL10A,ZBTB2,FABP5,RBIS,IRF2,MRPL16,MCM6,HERC4,COMMD8,CRAT,IRF8,ABHD10,ZBTB42,SEC14L1,RPL26,SSRP1,TNKS,CRYAB,COX4I1,AK2,INPPL1,ACP2,PSRC1,ATF3,RBM27,RAD21,SUMO3,CETN3,SSU72,JUN,TENT4A,LORICRIN,CETN2,POP7,HSD17B10,SRSF2,DDX1,APTX,LARP4B,MCM8,EID1,IGFBP4,COPS5,RPP14,ESR2,TMEM70,STUB1,OPRK1,THRAP3,TOR2A,PARM1,TST,DHX15,WTAP,SRI,LUC7L3,SLC7A14,PIAS1,NDUFS8,UTP15,TCIM,DCAF11,MAK16,GRPEL1,EPOP,RPS13,SLC35A2,PHAX,LGALS3,DUSP6,BRMS1L,INO80E,SLX1A,BCL6,RB1,PAK1IP1,TRIM11,CDK7,TCEAL7,VMP1,SAP30L,PCNA,SLC8A1,HNRNPA1,SNRPG,THOC2,RSL24D1,AKAP17A,HSPD1,DYRK2,MAIP1,NKX3-1,BUB3,TSPAN5,ALKBH2,OGG1,NLE1,DMAP1,SOD2,GLRX2,LSM10,HIKESHI,TTC4,MRPS18A,SURF2,FKBP10,TSN,LPXN,FTH1,SPIN3,ZGLP1,SP1,RANGRF,TXNDC12,KDM2A,BACH1,MAFG,RIOX2,TIMP1,RPL7,NOL4,SRP54,RGS2,PAXX,MRPL23,DGCR8,CALU,RBM15B,COIL,OAS1,HBB,PEX3,PAX6,HNRNPH3,PEA15,NDUFB6,POLR2L,TGFB2,IRF2BPL,TAF11,RAG1,VDAC1,SH3GLB2,DDX46,FAM50B,ZMAT3,RNASEL,UAP1,MLH3,IL23A,RUNX1,EED,TSEN54,FGF23,IDH3B,RNASET2,PSMB10,NGDN,UBE2A,ACTL6B,VEZT,MAPKAPK5,MAP1S,ST6GALNAC3,TXN,TXNRD2,ZRANB2,ZBTB17,SERPINI1,UBL5,PSMA6,OXCT1,CSNK2A1,LITAF,SERPINB1,OIP5,GTF2I,CDC16,POLR2G,ACAT1,SART3,PTGES3,TUBB4B,NOP58,HPGDS,GPX7,ABCG2,MAPKAPK3,UCHL3,CFAP68,PRKACB,PNMA1,CIPC,RNF146,GSTK1,UNC45A,MRPL52,NHEJ1,STK11,OAZ3,SNRPB,JMJD8,MED9,PPIB,HUWE1,CDC40,NOP16,PPIF,NACC2,POU5F1,FBXO25,THUMPD1,TF,SMAD4,NME2,BATF,MAP2K6,HNRNPH2,USP16,PTGES,NUP37,SLC13A5,ALKBH3,DDX50,RPS28,BRMS1,BGLAP,TDP1,UTP6,H2BC1,RDM1,TSG101,FBXO32,KLF12,CDK4,OAT,POLDIP3,DDX42,NEO1,NHP2,ARPP19,ZMYM3,MRPL9,CAVIN2,PSMB5,PLEKHO2,GOLGA7,SOX9,PRKRA,H2BC14,ZNHIT1,HSPA8,KLF1,FEM1B,NFKB1,USP2,TGIF2,PSMB9,SPHK2,GRPEL2,MRPL41,CSNK2B,NPM3,POLD2,TTR,CSTF3,DUSP18,SNRNP27,FAF1,OPTN,SMARCD3,NF2,PELP1,WDR3,WDR5B,HNRNPC,CLIC2,CPT2,ARL2BP,MAPK4,MTHFS,TSPAN15,SERPINH1,ACADS,SMARCB1,RFC3,CALR,PPAN,ATF4,CUL3,APPBP2,SDHAF4,CSE1L,MKLN1,BABAM1,MRPS35,ELF1,FAS,NR1H2,IL6,SLC30A5,GTF2H4,PIP4P1,FAM3C,EMX1,ALPL,CSNK1A1,CAMP,OGDHL,GLYAT,PSMA1,MAX,SPP1,SPRED1,ATP5F1D,NOP53,UBE2M,RASL11A,LYAR,MRPS34,NOTCH2,ING5,PSMD3,APEX1,SMAD3,MRPL20,BUD31,TAB1,S100A8,METTL18,RIT2,EXD2,MTF1,SNRPB2,MMAA,SPATA2,RSPH1,CHCHD2,PCGF2,RTRAF,PPIA,LIPT2,GTF2F2,SHOC1,TADA1,MLLT11,PCSK2,NLRP1,SDHAF2,MCAT,FAM20B,UBP1,PYCR2,POMP,SMN1,H2AZ1,OARD1,PAGR1,AIP,TADA3,MYRF,PLA2G15,PRDX4,FBXL4,SHC1,KPNA6,RPS7,MRPS33,SMURF1,SMAP2,PPM1K,MRTO4,RPRD1A,EVA1A,PRCC,DLST,CD274,SPTBN1,PPIL4,UBL4A,DYRK1A,RBM5,PSMD14,RPF1,FAHD1,RPAIN,ABCF1,GGPS1,MRPL11,ALKBH4,GFM1,F9,TESC,PCBD1,PRKD3,GFI1,DLAT,UBE2D1,MED10,CMTR1,RBBP9,BHLHE40,PPARG,PSMC1,TIMM29,H1-5,CHPF,RPP25,RNF113A,SLU7,CD2BP2,ISG20L2,FTL,ADH1A,NSG1,DDX39B,FBXW7,CIART,CD2,MMUT,SERTAD2,TSEN34,PHB1,CAMK2G,GCHFR,TEX264,DNAJC2,GPC1,ATXN1L,PPP4C,ZBTB33,NR2F6,RBM7,CASC3,ARL4D,ADD1,CPEB1,CNDP2,MRPL53,RERE,ZBTB45,GTF2A1,RPRD1B,PAX9,H1-1,FEM1C,HNMT,NOL12,HDAC11,FYTTD1,ZNF436,MRPS17,GATAD1,DCTN3,MRPS7,HCFC2,TUBG1,RMI1,MEF2A,HNRNPDL,CCDC174,SUB1,UBE2S,GTF2IRD1,NAA11,DNAJC7,RMI2,FOXD3,COTL1,VEGFA,GOSR2,EEF2,IFI16,TFPT,TP53INP2,ZNF24,WDR20,PYROXD2,ACTB,ASF1A,PPP1R8,ZNF207,PPTC7,SLPI,AQP3,IRF9,SLC25A5,DNAJC8,GTF2E1,TAF1D,TOR4A,NRBF2,OSBP,MRPS23,MORC2,RPL13A,PDE12,PHF12,CDK6,PRPF18,P4HA2,PIR,GDI2,TAX1BP3,PHYH,LDHAL6B,ETFBKMT,COMMD5,ZBED1,MACROH2A1,MYC,SKP1,CGAS,UQCC2,SOX3,MAEA,KPNA1,PRMT6,PSMA4,STXBP1,ZHX1,NOP9,F10,CRTC2,MRPL51,FSTL1,SIX5,SELENOM,ETV6,RGS10,DCLRE1C,MMP9,STAT1,NKRF,SMC4,RACGAP1,MED31,POP5,DCUN1D1,TRIM34,THAP7,UPF3B,PRL,PYCR1,CBX7,WDR82,GHRL,LMO2,CDC20,NABP1,PRIM2,CCNA2,EID2B,UQCC3,POLR1B,TULP3,FGR,MDM2,NUDT7,TIMM13,HP,RPGRIP1L,GCFC2,UBE2W,AURKAIP1,RPL23,NR0B1,SLC25A10,MED22,HR,PSMB2,SMU1,DEK,HSPA5,H2BC9,PDLIM4,EIF2D,RTCB,ALKBH5,RGCC,HSCB,RBPJ,MTERF2,RARRES2,TFE3,HSP90AB1,FURIN,GTF2H5,TLE1,CAND1,FUBP3,TREML1,ERO1A,ARL14EP,DCAF16,FOSL2,SRSF10,E4F1,SDCBP,XRCC5,EZH2,AMACR,CHID1,MAP2K3,BAP1,MED17,SLC39A7,SNRPE,HFE,CEP85,EHBP1,FXN,MRPS26,TWIST2,PRPF19,ACP6,ARG2,TFB1M,NEU1,SYVN1,PROX1,RUVBL2,SIAH2,H2BC11,CCR2,ZBTB16,RLIM,ISG15,SPTAN1,OLR1,CHMP1B,ELOC,B2M,PGA4,CCAR1,ING2,GFM2,CDC26,POLE4,MXD1,CTNNBL1,RPS11,TRAPPC1,BRD9,ID4,IDH1,HSP90AA1,PTPN4,GON7,SELENOP,FOXN2,MSX2,RFC4,AKAP8L,AGER,EYA3,MYO6,CDKN2AIP,PGM1,ZNF622,RPL4,TOP1,RAD23B,ZMYM2,AFTPH,SHOC2,GTF2H2,HNRNPD,SERPIND1,PPME1,RPS2,ISG20,TSNAX,DNAJB4,GTF3C4,TIMM10,EID2,AUH,METTL14,ALB,HDAC5,CTSD,NDUFB5,COL1A2,VTA1,ACADSB,RERG,SMAD1,PHF1,PYM1,ETFB,CCT8,TAF10,DPY30,TGFB1I1,MIOS,CHAMP1,ANAPC11,CWC15,LDOC1,CTSA,PTPN11,SPOP,UBB,PSMB6,USP15,TAB2,PPP1R12A,ZNF473,PTEN,CLPX,NFYA,LSM5,PGR,ATF1,BTG1,RPS27A,ABHD17A,PAPOLA,HRAS,HOXB1,TIMM23,CSH1,PRDM4,PPM1B,EMG1,NUP153,EXTL2,HILPDA,GLRX5,ZBTB39,NDUFS2,RBM22,GALC,PEG10,RBM18,INTS10,GANAB,NXT2,PSKH1,CNPY3,TIMP3,IL12A,NUDT9,PADI2,RPS17,RPS5,SYCE3,HBP1,PDHB,PLAGL1,GPC4,MGMT,MAF1,AGK,ACACA,FKBP14,TESK2,CDK9,NAB2,UHMK1,ADK,FCF1,PDSS2,PSMC4,STAP1,BUD23,CNOT2,HNRNPL,RPS6KA4,ABITRAM,CSTB,YPEL5,UBE2N,SGMS2,HTRA2,SERPINB10,SF3B1,ZNF326,CHST2,EP300,MCOLN1,SUMO1,POMT2,CTSB,WNT7A,PDIA6,COP1,PRPF31,DNTTIP1,MYCT1,LYZ,DBT,RNF7,CCND1,POLR2I,C1D,APOBEC3A,MRPL12,SETD3,CCDC22,XPOT,PMM2,CYP27A1,MRPL49,MITF,SF3B4,ZNF175,COX10,CAPG,H2AC6,CFL2,DNAJB6,BANF1,TRA2B,BCCIP,SUPT5H,LDB1,ENY2,RCHY1,CBX5,RAN,POLR2D,KLF9,CREB3,ELK4,SELENOF,ATP6V1D,MCM3,HSPB8,LMNB1,SNRPA,UBE2V2,KMT5B,CNOT7,HNRNPA0,ETFA,TXNL4A,PCK2,MEF2C,TRA2A,PYCARD,BOLA3,BNIP3L,SUCLG2,MZB1,FAM222B,RPS26,CBR4,POLR1H,ARHGAP15,FHIT,SMUG1,DXO,EIF2AK2,TGFB3,RAPGEF5,MTHFD2L,PQBP1,PDIA3,FMOD,DBH,CCNB1,MRPL34,SRP14,PAFAH1B2,SKAP2,NUFIP2,FBXO3,FOXP1,KIN,SRSF7,RPL27,IRF2BP1,TAF5L,ILF2,IDE,TAPT1,RRP7A,USP39,FGL2,ADRM1,NDUFB7,CREB1,ZCCHC7,EIF1AD,DTL,IK,YPEL4,RIOK2,COA4,MED11,THAP1,FAM193B,SRSF8,MRPS18B,ZC3H11A,HBA1,TRAF7,PSME2,FGF1,RPSA,MBD3,EGLN3,APOBEC3H,UTP23,PSMB1,PPP1R26,AIPL1,DHX38,MYBL2,PPARA,LSM4,BAG3,FAF2,NAA15,CACNB4,RETREG1,CDC7,HNF1B,HEXB,JUNB,PPP1CC,SUPT7L,MRPL36,MIF,SCG3,DLX1,JADE1,F7,ATP5F1E,LIPA,CCAR2,RBM42,JAML,NAA35,UQCRC2,NEK2,MPHOSPH6,NEK7,TIMM17A,ELOF1,RAB5A,NGB,TNFAIP8,MRPL47,TRIM27,NOVA1,HIRA,PSMC3,AMELX,PPWD1,SMAD2,SCNM1,TERC,KANSL3,UBE2L3,CCT2,NGRN,DYRK1B,SAP30BP,GTF3C3,RPL3,IRF3,ARPC2,PWP2,HNRNPAB,MAPK10,ERLEC1,AATF,AMT,PHB2,GCA,PMPCA,RXRG,TNFAIP6,NFKBIL1,H2BC17,FTSJ3,TWNK,HEBP2,CBR3,SP2,PNP,SETD5,HADH,TMA16,MTG2,POLR2B,PHF23,NCAPG2,CBX3,TOR3A,SMAD9,SPON1,FERMT2,PML,POLD4,BACE1,KARS1,LRIF1,TMUB1,PSMB4,SPRN,ABCE1,KRR1,TOPBP1,HEXIM1,GSTP1,FOS,MRPL57,ZNF687,RFX5,THOC6,NEDD8,CAB39,PHF13,EXOSC3,GTF2F1,CEBPG,HOXB8,MDC1,ZNF22,FRMD8,TIMM8B,CDKL2,TMEM179B,RBM3,IGF1,OLA1,CDKN2D,ZNF451,NPC2,EEF1A1,NFE2L2,TUBB,CHTOP,RUVBL1,IPO8,DUSP26,PSMA2,POLR3B,SNRPA1,GIMAP2,MAD2L2,ATP5F1A,CPSF2,RPS4X,TRMT61A,PSMD1,PSMD4,HYPK,MRPL33,RAB32,CUL2,TRIM22,EDF1,ACSS2,INO80C,METTL15,NXT1,MRPS18C,RFC2,RSAD2,CDC23,STAR,RADX,TMT1A,NONO,PRDX3,DRG1,TNRC6C,THOC3,CD63,MPIG6B,CGRRF1,ATPAF2,DPPA2,PPM1D,SAP30,SSBP1,SMARCE1,MRPS11,KLC2,CLIC4,STAC3,AP5S1,S100A11,RIMOC1,XPO5,CDCA7L,DRG2,POLR3H,ANAPC15,RALYL,LSM8,COMMD3,TCEA1,PPT1,DKC1,DCP2,CCND3,EIF3E,HDHD3,SIRT7,PAOX,CXXC5,GJC1,CREB3L4,THOC1,PSMD10,CTSK,KLF3,EIF4A3,AKR1B1,MNAT1,ZNF609,YIPF5,IFI35,RNF126,RPS29,GIT2,MTAP,SNAPC3,EGR2,RFXANK,CDK1,TRIM24,PSMD6,FZR1,STAT5A,ABHD16B,TFDP2,NAA50,MACROD1,RPS14,SPMIP6,TCOF1,MED27,MCMBP,ISCA2,NUDT19,ZBTB18,SNRPD2,UBE2D3,TBK1,FBXO11,THAP2,WBP2,API5,ODAM,SGF29,MTX2,MED23,APOBEC3B,RPA2,RNF14,PSPC1,SUFU,FAM76B,RING1,ZBTB26,TIMM8A,GLO1,RBMX2,NICN1,RNF8,FOXC2,ZMYND11,FOXP3,STK16,SOD1,INPP4A,MPV17L2,IRF1,PPIG,PRPF4,IMP4,NUP62,RPL35,CMKLR2,BECN1,TAF2,PABPC5,COL3A1,MAGEC2,MXI1,MSH6,MED30,SNRPN,MRPL40,TNFSF13,DNAJC10,KRT8,MED4,MED29,RPS9,FAAP100,CACYBP,H3C1,ISCU,PTPN5,RPS20,GEMIN8,PDP2,CTDSPL2,DUSP21,MORC4,NR4A2,ASCC1,PGAM1,CENPM,RPL23A,HLF,CTSC,KLHL7,SUMO2,SLA2,MED13L,TP53,COPS7A,NUDT12,HMGA1,TRIM8,PCCB,PDE9A,LSM2,POLR2F,E2F4,ESD,CTDSP2,LIMD2,CPSF4,APEX2,EGR1,DBR1,SPC24,SNAPC2,RNF187,DUSP10,TXNRD1,CTNNB1,CCNH,NCBP2,SNAP23,CXXC1,MCL1,SRSF4,VEGFC,LDB2,IRF7,UTP25,CDC37L1,DENND2D,IQSEC1,FBXO7,SRPK2,TRIP4,NDUFS3,CTBP1,ZNF692,NR1I3,GLE1,CCDC106,TRIM6,TENT5C,HAX1,SKIC8,TMSB4X,ANP32A,MAD2L1BP,RPA3,EIF4E,PDHA1,BARX2,DDRGK1,TAF7,FMO1,RPS15,HMGB1,CLP1,PRMT5,CDK5R1,KLF4,ZC3H14,COX17,APBB3,UBE2I,ROCK1,PPIH,NUDT1,BTBD10,TCF21,PHC1,ZBTB38,F2,E2F6,NUP50,RBBP7,POLR1D,ELP3,OSGEP,DHX9,MBD5,CHI3L1,PIP5K1A,PYDC2 |
| 3.682e-10 | -21.72 | organelle lumen | cellular component | GO:0043233 | 6022 | 1931 | 19108 | 5553 |
BMPR2,DCK,SMARCA5,SCG2,IL15,GRAP,EEF1AKMT3,PAK6,MRPS16,POGK,BCL9,PRKX,GTF2B,TAF9,PLPPR1,TFCP2,STX6,TRIM68,PPM1G,PHF21A,SURF6,AKIP1,PNMA2,ZBTB14,PDE2A,SQSTM1,MYG1,YWHAZ,NFYB,CSTA,PYGB,CENPW,MORF4L1,BRIX1,PIH1D1,MTDH,ELK3,RPS23,TOLLIP,RPL18,GADD45A,CREBZF,BPNT2,LANCL2,SAMHD1,NDUFB4,CDKN1A,DNASE1L1,RRAGA,FKRP,CRABP2,S100A10,MAGED2,P3H1,MPHOSPH10,HOXC4,NBN,MEAF6,RORB,AGO1,CHRDL1,BCL2L1,PIWIL4,PRKCA,NUDT2,NSMCE3,ZCCHC17,BRCA1,ABHD5,ZCRB1,SETD7,SPRY1,ZCCHC9,DAG1,MATR3,TYMS,CHMP1A,CTDSP1,ZNF593,NUDT16,DROSHA,SOX2,CHCHD4,CMAS,DCUN1D3,NIBAN2,PCGF6,SNRNP70,UBE2V1,GABPA,PPP1R10,CLPB,RPL12,DNAJB9,CD4,CRYM,PNMA3,POLE3,NCOA5,PSMC5,CMPK1,COPE,TERT,CDC73,FAM20C,VPS72,PLEKHA8,COPS2,TNIK,NDN,SIVA1,STK24,DCAF5,XAF1,ATP6V1A,LIG3,PDAP1,PLG,H1-10,AKT1,CDK8,NAB1,ZNF397,COPS7B,KDM1A,HADHA,DMTF1,TNFAIP8L3,POLB,RARS1,FAM118B,DFFA,NTMT1,SATB1,MTA2,SUV39H1,HECTD1,NFKBIA,SFTPC,LAMB2,VWF,GTF2A2,CHRAC1,AGPAT5,HNRNPF,MTRES1,METTL21A,ANAPC2,ZNF322,ANAPC4,MRPL50,FASLG,SIN3A,GNAI3,LMNA,WDR77,RPL27A,ALYREF,PPID,GGH,CD1E,EXOSC4,TRIM45,TCEAL1,SRGN,RPS12,ARL4A,FBXL3,ID1,CREBBP,TRMT5,CENPL,MRPL10,TRIM37,PRM1,RPAP2,PHYKPL,PLAC8,CRTAP,HP1BP3,RPS24,ANP32B,CASK,TRIM5,CAPN1,ACOT13,PSMB7,SLC35F6,CDK2AP2,CSTF2T,SMAD5,VCPIP1,ORC6,STN1,STX12,ACOT8,INTS12,SRSF1,RBBP8,LRWD1,XPO1,DHRS4,LYPLA1,IGFBP3,NKAP,PSMD12,FOXA3,SNRPD3,BRAP,GPX1,MRPL24,ARFGEF1,DAPK3,POLL,STOML2,CRADD,VIRMA,PRKCB,CRKL,PFKFB2,HNRNPK,STAT6,STAT2,SEC13,METTL22,RPS10,RAB27A,HDAC3,PAAF1,GMNN,RCL1,RFC5,SDF2L1,PSMD7,PRR13,PDIA2,MAD2L1,KDM4B,ARGLU1,XBP1,PPP5C,ABHD14B,PLD3,JAK2,DTYMK,NSA2,WDR12,LCMT1,NDC80,SRC,EXOSC8,DDX23,HGS,RNF34,MALSU1,ANAPC16,NFE2L1,SETD9,FASTKD5,CDC5L,ERP29,NOB1,PNO1,S100B,MACROH2A2,OS9,RAB33B,RPF2,MRM2,TOP2B,RBM12,CDK20,IGF2BP1,BCKDK,CKS1B,S100PBP,DNAJC19,TXNRD3,NRDE2,EAF2,WDR55,NUP42,AKT2,CST3,KIF2A,RETN,ENC1,SMDT1,SDHB,LSM6,ZNF655,HSP90B1,STK4,ZNF174,RFXAP,ATP5F1B,FAU,PSEN1,MMP14,KCTD10,NOL7,SF3A1,PPP3CA,PSMA5,CCNY,GH1,SNRNP40,ECD,MIDEAS,CGGBP1,USP13,SERPINA1,MRPS21,AIFM1,POLR3F,PIP4K2C,NUP107,CYRIB,DNLZ,CEBPE,RNF20,UBN1,ACTL6A,VTI1B,BAALC,IDH3A,PRKAB1,ARMC8,MRPL22,CYB5R3,UBE2B,VDAC2,HSD17B8,CBFB,FANCG,ZBTB25,PTPN1,ACOX1,H2BC12,CCDC92,IVNS1ABP,RPS16,NUPR1,DHX16,PCGF3,MRPL13,EZH1,TRAF2,HINFP,ATP5PB,MARS1,SDC4,NME4,HEXIM2,SNAPC5,DDX39A,USP3,NT5C3A,PSMA3,POLDIP2,MFAP3L,CSNK1E,SUGP1,CITED1,IL2RG,PROS1,RAD1,NOSIP,SAP18,OLFM2,CFDP1,ABCC5,PSMB3,SUPT4H1,CFL1,TRMT6,CMC4,SDHAF1,VPS54,UBA52,TASL,SMNDC1,ACTR1B,CEP19,ADRA1A,ERCC3,ZBTB6,MPG,HSPE1,CCDC86,ZMAT2,NMRAL1,EDEM2,HS3ST1,NMI,RSRC1,DDX5,NFE2,NUF2,SNIP1,MCM4,IRF4,DR1,REXO2,VRK1,HEY2,RBFOX2,GRAP2,RPL7A,MECP2,POU1F1,HCFC1R1,DNTT,TIMMDC1,WRAP53,SPR,HNRNPA2B1,ACTN4,CLU,MRPL17,SMCHD1,JUP,AGA,BIRC5,SF3B5,POLR2C,RPS3,NDUFB8,DCTPP1,DSN1,GNPAT,UGDH,IDH2,SENP5,IL12B,EGLN2,GID8,DUSP3,PARP11,MSX1,HEXA,PCSK9,CPNE1,RBBP4,POLR3GL,FEN1,NUCKS1,AK3,KHDC4,SMYD3,AGAP2,PAK5,GRSF1,MRPS9,EXOSC1,POLA2,GJA1,RBM17,CD2AP,ATG7,H2AX,AR,EWSR1,SPATS2L,GTF2E2,ZMAT5,WBP11,YAF2,WEE2,RP2,UBE2E3,KIT,RPP21,CTNNBIP1,TP53TG5,PRSS23,ACOT6,SNAI2,SERPINB9,SERPINC1,HSPB6,PLSCR1,MAGOH,CDK5,TEX12,RBM34,EHHADH,RPL7L1,NR2E1,MCPH1,TIA1,CDK5RAP3,UFD1,CFAP68,UCHL3,PNMA1,PRKACB,GSTK1,CIPC,RNF146,UNC45A,MRPL52,NHEJ1,STK11,OAZ3,SNRPB,JMJD8,HUWE1,PPIB,CDC40,NOP16,PPIF,MED9,NACC2,POU5F1,NME2,FBXO25,THUMPD1,TF,SMAD4,VEZT,TXN,MAPKAPK5,MAP1S,ST6GALNAC3,ZRANB2,ZBTB17,TXNRD2,CSNK2A1,SERPINI1,UBL5,PSMA6,OXCT1,SERPINB1,OIP5,LITAF,CDC16,POLR2G,ACAT1,GTF2I,TUBB4B,NOP58,HPGDS,SART3,PTGES3,ABCG2,MAPKAPK3,GPX7,IRF2BPL,TGFB2,TAF11,VDAC1,SH3GLB2,RAG1,DDX46,FAM50B,MLH3,ZMAT3,RNASEL,UAP1,TSEN54,EED,IDH3B,FGF23,IL23A,RUNX1,NGDN,UBE2A,ACTL6B,RNASET2,PSMB10,SURF2,FKBP10,TSN,ZGLP1,SP1,FTH1,LPXN,SPIN3,RANGRF,RIOX2,TXNDC12,KDM2A,BACH1,MAFG,SRP54,TIMP1,NOL4,RPL7,CALU,COIL,RBM15B,RGS2,PAXX,MRPL23,DGCR8,PEX3,PAX6,HNRNPH3,PEA15,OAS1,HBB,NDUFB6,POLR2L,APEX1,PSMD3,TAB1,S100A8,METTL18,RIT2,SMAD3,BUD31,MRPL20,MTF1,SNRPB2,MMAA,EXD2,RTRAF,PPIA,RSPH1,SPATA2,CHCHD2,PCGF2,GTF2F2,SHOC1,TADA1,LIPT2,NLRP1,SDHAF2,MLLT11,PCSK2,MCAT,FAM20B,UBP1,SMN1,PYCR2,POMP,SMARCB1,RFC3,PPAN,CALR,TSPAN15,ACADS,SERPINH1,MKLN1,BABAM1,ATF4,APPBP2,SDHAF4,CUL3,CSE1L,FAS,NR1H2,MRPS35,ELF1,PIP4P1,IL6,SLC30A5,GTF2H4,EMX1,FAM3C,PSMA1,GLYAT,ALPL,CSNK1A1,OGDHL,CAMP,NOP53,UBE2M,ATP5F1D,MAX,SPP1,SPRED1,NOTCH2,ING5,RASL11A,LYAR,MRPS34,NFKB1,USP2,TGIF2,HSPA8,KLF1,FEM1B,CSNK2B,MRPL41,SPHK2,PSMB9,GRPEL2,TTR,CSTF3,NPM3,POLD2,SNRNP27,DUSP18,NF2,FAF1,OPTN,SMARCD3,PELP1,WDR5B,WDR3,CPT2,ARL2BP,MAPK4,MTHFS,CLIC2,HNRNPC,MAP2K6,HNRNPH2,BATF,NUP37,SLC13A5,DDX50,ALKBH3,USP16,PTGES,UTP6,TDP1,RPS28,BRMS1,BGLAP,FBXO32,KLF12,H2BC1,RDM1,TSG101,POLDIP3,CDK4,OAT,NHP2,ARPP19,DDX42,NEO1,MRPL9,CAVIN2,PSMB5,ZMYM3,PRKRA,H2BC14,ZNHIT1,PLEKHO2,GOLGA7,SOX9,SOD3,SF3B6,MECR,SNX20,FKBP4,GINS4,DEFB1,PC,TOPORS,KLK6,CXCL1,OGN,LYPLA2,SRSF12,PRKAG1,GABPB1,COMMD9,RNF208,PPIL3,SNRPD1,TRMT10B,ZNF330,MAGOHB,ACO2,BAHD1,MRPL18,SHPRH,CHCHD1,SDC2,GEMIN7,CDKN1B,G2E3,NDUFAB1,MEF2B,EEF1E1,HINT1,GTPBP2,LAMP2,CIRBP,UBLCP1,SYNCRIP,ZNF501,ORC5,CBLL1,PRELID1,PRMT2,ZBED4,MAP3K14,PARP2,DCAF4,BAZ1B,SHMT1,UPRT,PPP1CB,PRRC2A,RRN3,ACAA2,PRDX6,MGAT4A,COPS4,MPST,LIAS,MTA3,TRMT112,IER2,CPSF1,NUP35,GINS3,KPNA2,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X17,ZC3H14,POLR2F,E2F4,PDE9A,PCCB,LSM2,ESD,APEX2,CPSF4,CTDSP2,LIMD2,EGR1,SPC24,DBR1,SNAPC2,TXNRD1,CTNNB1,DUSP10,RNF187,SNAP23,CXXC1,CCNH,NCBP2,IRF7,VEGFC,LDB2,UTP25,MCL1,SRSF4,IQSEC1,FBXO7,DENND2D,TRIP4,SRPK2,CDC37L1,PTPN5,RPS20,GEMIN8,H3C1,ISCU,CTDSPL2,PDP2,MORC4,NR4A2,DUSP21,PGAM1,CENPM,ASCC1,KLHL7,SUMO2,SLA2,MED13L,TP53,RPL23A,HLF,CTSC,NUDT12,HMGA1,COPS7A,TRIM8,NEK7,MPHOSPH6,RAB5A,TIMM17A,ELOF1,NGB,TNFAIP8,MRPL47,TRIM27,AMELX,PPWD1,NOVA1,HIRA,PSMC3,TERC,KANSL3,SMAD2,SCNM1,CCT2,UBE2L3,DYRK1B,NGRN,MBD3,EGLN3,APOBEC3H,RPSA,PPP1R26,UTP23,PSMB1,DHX38,MYBL2,AIPL1,LSM4,BAG3,PPARA,HNF1B,CDC7,RETREG1,HEXB,PPP1CC,JUNB,FAF2,NAA15,CACNB4,SCG3,DLX1,SUPT7L,MRPL36,MIF,RBM42,CCAR2,JADE1,F7,LIPA,ATP5F1E,UQCRC2,NEK2,JAML,NAA35,RPL27,SRSF7,ILF2,RRP7A,TAPT1,IDE,IRF2BP1,TAF5L,ADRM1,NDUFB7,CREB1,USP39,FGL2,ZCCHC7,EIF1AD,DTL,IK,YPEL4,MED11,COA4,RIOK2,ZC3H11A,THAP1,FAM193B,SRSF8,MRPS18B,FGF1,HBA1,PSME2,TRAF7,PYCARD,TRA2A,MEF2C,BOLA3,FAM222B,MZB1,BNIP3L,SUCLG2,ARHGAP15,POLR1H,FHIT,SMUG1,RPS26,CBR4,EIF2AK2,DXO,PDIA3,PQBP1,FMOD,TGFB3,RAPGEF5,MTHFD2L,PAFAH1B2,SRP14,DBH,CCNB1,MRPL34,FBXO3,NUFIP2,FOXP1,KIN,SKAP2,PSMA2,DUSP26,GIMAP2,SNRPA1,POLR3B,IPO8,MAD2L2,ATP5F1A,PSMD1,PSMD4,CPSF2,TRMT61A,RPS4X,MRPL33,RAB32,HYPK,TRIM22,CUL2,EDF1,RFC2,ACSS2,INO80C,MRPS18C,NXT1,METTL15,STAR,RADX,TMT1A,RSAD2,CDC23,PRDX3,TNRC6C,DRG1,NONO,CAB39,NEDD8,PHF13,EXOSC3,GTF2F1,CEBPG,HOXB8,MDC1,TIMM8B,FRMD8,ZNF22,IGF1,CDKL2,TMEM179B,RBM3,CDKN2D,OLA1,NFE2L2,ZNF451,EEF1A1,NPC2,RUVBL1,TUBB,CHTOP,TOR3A,SMAD9,FERMT2,SPON1,CBX3,BACE1,POLD4,PML,TMUB1,PSMB4,KARS1,LRIF1,KRR1,TOPBP1,SPRN,ABCE1,FOS,MRPL57,HEXIM1,GSTP1,THOC6,RFX5,ZNF687,GTF3C3,RPL3,SAP30BP,IRF3,ARPC2,AATF,AMT,PWP2,HNRNPAB,MAPK10,ERLEC1,PHB2,PMPCA,RXRG,GCA,TWNK,HEBP2,CBR3,SP2,TNFAIP6,NFKBIL1,H2BC17,FTSJ3,HADH,TMA16,MTG2,PNP,SETD5,PHF23,NCAPG2,POLR2B |
| 3.682e-10 | -21.72 | intracellular organelle lumen | cellular component | GO:0070013 | 6022 | 1931 | 19108 | 5553 |
SH3GLB2,VDAC1,RAG1,IRF2BPL,TGFB2,TAF11,FGF23,IDH3B,TSEN54,EED,RUNX1,IL23A,ACTL6B,UBE2A,NGDN,PSMB10,RNASET2,FAM50B,DDX46,MLH3,UAP1,RNASEL,ZMAT3,RANGRF,RIOX2,MAFG,BACH1,KDM2A,TXNDC12,TSN,FKBP10,SURF2,SP1,ZGLP1,SPIN3,FTH1,LPXN,PEA15,HNRNPH3,PAX6,PEX3,OAS1,HBB,POLR2L,NDUFB6,SRP54,NOL4,RPL7,TIMP1,COIL,RBM15B,CALU,DGCR8,MRPL23,PAXX,RGS2,MRPL52,UNC45A,STK11,NHEJ1,PRKACB,PNMA1,UCHL3,CFAP68,GSTK1,RNF146,CIPC,POU5F1,NACC2,NME2,SMAD4,TF,THUMPD1,FBXO25,JMJD8,SNRPB,OAZ3,PPIF,NOP16,CDC40,PPIB,HUWE1,MED9,ZBTB17,ZRANB2,TXNRD2,CSNK2A1,OXCT1,UBL5,PSMA6,SERPINI1,VEZT,TXN,ST6GALNAC3,MAP1S,MAPKAPK5,HPGDS,NOP58,TUBB4B,PTGES3,SART3,MAPKAPK3,ABCG2,GPX7,OIP5,SERPINB1,LITAF,POLR2G,ACAT1,CDC16,GTF2I,CSTF3,TTR,NPM3,POLD2,SNRNP27,DUSP18,TGIF2,USP2,NFKB1,FEM1B,HSPA8,KLF1,MRPL41,CSNK2B,GRPEL2,PSMB9,SPHK2,WDR5B,WDR3,MTHFS,MAPK4,ARL2BP,CPT2,HNRNPC,CLIC2,NF2,SMARCD3,OPTN,FAF1,PELP1,TDP1,UTP6,BGLAP,BRMS1,RPS28,KLF12,FBXO32,TSG101,RDM1,H2BC1,HNRNPH2,MAP2K6,BATF,DDX50,ALKBH3,NUP37,SLC13A5,PTGES,USP16,PSMB5,CAVIN2,MRPL9,ZMYM3,ZNHIT1,PRKRA,H2BC14,GOLGA7,SOX9,PLEKHO2,POLDIP3,OAT,CDK4,ARPP19,NHP2,NEO1,DDX42,MMAA,SNRPB2,MTF1,EXD2,PPIA,RTRAF,PCGF2,CHCHD2,RSPH1,SPATA2,APEX1,PSMD3,RIT2,METTL18,S100A8,TAB1,MRPL20,BUD31,SMAD3,UBP1,FAM20B,MCAT,SMN1,POMP,PYCR2,TADA1,SHOC1,GTF2F2,LIPT2,SDHAF2,NLRP1,PCSK2,MLLT11,NR1H2,FAS,MRPS35,ELF1,PIP4P1,SLC30A5,GTF2H4,IL6,PPAN,CALR,RFC3,SMARCB1,SERPINH1,ACADS,TSPAN15,MKLN1,BABAM1,CSE1L,CUL3,APPBP2,SDHAF4,ATF4,NOP53,ATP5F1D,UBE2M,SPP1,SPRED1,MAX,ING5,NOTCH2,MRPS34,LYAR,RASL11A,EMX1,FAM3C,PSMA1,GLYAT,OGDHL,CAMP,CSNK1A1,ALPL,GINS3,NUP35,CPSF1,IER2,KPNA2,MPST,COPS4,LIAS,MTA3,TRMT112,NAIF1,SUPT3H,STAMBP,RPL19,LLPH,VDR,ZHX3,SNAPC1,LSM3,LHB,PTHLH,MRFAP1,SNRNP48,PSME1,SP4,MSL2,DEDD,CDK12,HSBP1,IMP3,ACTR2,DVL2,DPH3,EDEM3,MINDY3,ANKRD10,PRELP,IP6K1,RNF40,COX19,TP53INP1,DNAJC3,MRPS28,MRPS25,SERPINA3,MED21,MZT2B,FAM107A,PHF7,MTG1,NR1I2,TRIM21,LUM,DPEP1,HDAC6,ADH1B,TCEA2,PC,GINS4,DEFB1,TOPORS,LYPLA2,OGN,CXCL1,KLK6,PRKAG1,SRSF12,SOD3,MECR,SF3B6,FKBP4,SNX20,BAHD1,ACO2,MRPL18,SNRPD1,PPIL3,GABPB1,COMMD9,RNF208,ZNF330,TRMT10B,MAGOHB,GTPBP2,HINT1,CIRBP,LAMP2,SYNCRIP,UBLCP1,PRELID1,CBLL1,ORC5,ZNF501,SHPRH,SDC2,GEMIN7,CHCHD1,NDUFAB1,MEF2B,G2E3,CDKN1B,EEF1E1,PPP1CB,RRN3,PRRC2A,ACAA2,MGAT4A,PRDX6,PARP2,MAP3K14,ZBED4,PRMT2,SHMT1,BAZ1B,DCAF4,UPRT,CETN2,POP7,HSD17B10,PSRC1,ACP2,INPPL1,AK2,TENT4A,LORICRIN,JUN,SSU72,SUMO3,CETN3,ATF3,RBM27,RAD21,IGFBP4,EID1,MCM8,RPP14,COPS5,ESR2,DDX1,SRSF2,LARP4B,APTX,FABP5,RASL10A,ZBTB2,PLCB1,PCYOX1L,NOC4L,ELK1,RPL8,GNAI2,CFAP20,PCLAF,HERC4,MCM6,MRPL16,IRF2,RBIS,TOR1B,CENPP,APEH,MFAP1,CALML5,TFIP11,TUFM,SSRP1,RPL26,COX4I1,CRYAB,TNKS,IRF8,ABHD10,CRAT,COMMD8,SEC14L1,ZBTB42,RSL24D1,THOC2,SNRPG,MAIP1,DYRK2,HSPD1,AKAP17A,HNRNPA1,SLC8A1,PCNA,HIKESHI,GLRX2,LSM10,DMAP1,SOD2,NLE1,MRPS18A,TTC4,BUB3,NKX3-1,OGG1,ALKBH2,TSPAN5,NDUFS8,PIAS1,SLC7A14,LUC7L3,MAK16,DCAF11,TCIM,UTP15,DHX15,TST,TOR2A,PARM1,THRAP3,OPRK1,STUB1,TMEM70,SRI,WTAP,RB1,SLX1A,BCL6,INO80E,BRMS1L,SAP30L,VMP1,CDK7,TCEAL7,TRIM11,PAK1IP1,PHAX,SLC35A2,RPS13,EPOP,GRPEL1,DUSP6,LGALS3,ABHD5,ZCRB1,BRCA1,SETD7,DAG1,ZCCHC9,SPRY1,NUDT2,PRKCA,PIWIL4,NSMCE3,ZCCHC17,NUDT16,ZNF593,CHCHD4,CMAS,DCUN1D3,SOX2,DROSHA,PCGF6,NIBAN2,MATR3,CHMP1A,TYMS,CTDSP1,PSMC5,NCOA5,CMPK1,COPE,FAM20C,TERT,CDC73,GABPA,UBE2V1,SNRNP70,PPP1R10,CD4,DNAJB9,RPL12,CLPB,POLE3,PNMA3,CRYM,ATP6V1A,XAF1,H1-10,AKT1,PLG,PDAP1,LIG3,NAB1,ZNF397,CDK8,COPS2,VPS72,PLEKHA8,NDN,TNIK,STK24,DCAF5,SIVA1,GTF2B,PRKX,TAF9,TFCP2,PLPPR1,STX6,DCK,BMPR2,EEF1AKMT3,GRAP,IL15,SCG2,SMARCA5,PAK6,BCL9,POGK,MRPS16,PDE2A,ZBTB14,SQSTM1,MYG1,NFYB,YWHAZ,PPM1G,TRIM68,SURF6,PHF21A,PNMA2,AKIP1,ELK3,MTDH,RPS23,TOLLIP,BPNT2,CREBZF,GADD45A,RPL18,SAMHD1,LANCL2,PYGB,CSTA,MORF4L1,CENPW,BRIX1,PIH1D1,HOXC4,NBN,MPHOSPH10,RORB,MEAF6,CHRDL1,AGO1,BCL2L1,RRAGA,FKRP,DNASE1L1,CDKN1A,NDUFB4,MAGED2,S100A10,CRABP2,P3H1,LRWD1,RBBP8,LYPLA1,DHRS4,XPO1,NKAP,IGFBP3,FOXA3,PSMD12,STN1,ACOT8,STX12,INTS12,SRSF1,CRKL,PRKCB,PFKFB2,HNRNPK,STAT6,GPX1,BRAP,SNRPD3,ARFGEF1,MRPL24,STOML2,POLL,DAPK3,CRADD,VIRMA,RAB27A,RPS10,HDAC3,PAAF1,RCL1,GMNN,RFC5,SEC13,STAT2,METTL22,PLD3,ABHD14B,PPP5C,WDR12,NSA2,DTYMK,JAK2,NDC80,SRC,LCMT1,DDX23,EXOSC8,PRR13,PSMD7,SDF2L1,PDIA2,XBP1,ARGLU1,KDM4B,MAD2L1,SATB1,HECTD1,SUV39H1,MTA2,LAMB2,SFTPC,NFKBIA,VWF,HADHA,DMTF1,KDM1A,COPS7B,TNFAIP8L3,POLB,NTMT1,DFFA,RARS1,FAM118B,SIN3A,GNAI3,LMNA,HNRNPF,AGPAT5,CHRAC1,GTF2A2,MTRES1,ZNF322,ANAPC2,METTL21A,MRPL50,FASLG,ANAPC4,ID1,FBXL3,CREBBP,ARL4A,TRMT5,CENPL,PRM1,MRPL10,TRIM37,ALYREF,RPL27A,WDR77,GGH,PPID,SRGN,RPS12,TCEAL1,TRIM45,CD1E,EXOSC4,VCPIP1,SMAD5,ORC6,PLAC8,PHYKPL,RPAP2,CASK,TRIM5,ANP32B,RPS24,HP1BP3,CRTAP,CAPN1,CSTF2T,CDK2AP2,SLC35F6,PSMB7,ACOT13,AIFM1,NUP107,PIP4K2C,POLR3F,CYRIB,DNLZ,ECD,USP13,CGGBP1,MIDEAS,MRPS21,SERPINA1,PRKAB1,IDH3A,ARMC8,VDAC2,UBE2B,MRPL22,CYB5R3,FANCG,CBFB,HSD17B8,CEBPE,RNF20,ACTL6A,VTI1B,UBN1,BAALC,HINFP,ATP5PB,TRAF2,EZH1,NME4,SDC4,MARS1,ZBTB25,PTPN1,IVNS1ABP,CCDC92,H2BC12,ACOX1,NUPR1,RPS16,MRPL13,PCGF3,DHX16,RAD1,CITED1,PROS1,IL2RG,NOSIP,SAP18,SNAPC5,HEXIM2,DDX39A,POLDIP2,PSMA3,USP3,NT5C3A,SUGP1,CSNK1E,MFAP3L,PNO1,NOB1,CDC5L,ERP29,OS9,MACROH2A2,S100B,RAB33B,HGS,ANAPC16,MALSU1,RNF34,FASTKD5,SETD9,NFE2L1,NRDE2,NUP42,EAF2,WDR55,AKT2,RETN,KIF2A,CST3,RBM12,TOP2B,MRM2,RPF2,IGF2BP1,CDK20,BCKDK,CKS1B,TXNRD3,DNAJC19,S100PBP,ZNF174,ATP5F1B,RFXAP,FAU,SDHB,SMDT1,ENC1,LSM6,HSP90B1,STK4,ZNF655,KCTD10,PSMA5,PPP3CA,SF3A1,NOL7,SNRNP40,CCNY,GH1,PSEN1,MMP14,RBBP4,AK3,NUCKS1,POLR3GL,FEN1,PAK5,AGAP2,KHDC4,SMYD3,GRSF1,IDH2,UGDH,GNPAT,IL12B,SENP5,HEXA,MSX1,DUSP3,PARP11,GID8,EGLN2,CPNE1,PCSK9,H2AX,AR,SPATS2L,EWSR1,MRPS9,EXOSC1,GJA1,POLA2,ATG7,CD2AP,RBM17,UBE2E3,RP2,RPP21,KIT,TP53TG5,PRSS23,CTNNBIP1,SERPINB9,ACOT6,SNAI2,ZMAT5,GTF2E2,WBP11,WEE2,YAF2,RBM34,RPL7L1,EHHADH,TIA1,MCPH1,NR2E1,UFD1,CDK5RAP3,MAGOH,PLSCR1,HSPB6,SERPINC1,CDK5,TEX12,CMC4,TRMT6,CFL1,ABCC5,PSMB3,SUPT4H1,UBA52,VPS54,SDHAF1,SMNDC1,TASL,OLFM2,CFDP1,CCDC86,HSPE1,NMRAL1,ZMAT2,RSRC1,NMI,HS3ST1,EDEM2,NUF2,NFE2,DDX5,ADRA1A,ACTR1B,CEP19,ERCC3,ZBTB6,MPG,MECP2,POU1F1,DNTT,HCFC1R1,ACTN4,CLU,HNRNPA2B1,WRAP53,SPR,TIMMDC1,SNIP1,IRF4,MCM4,VRK1,REXO2,DR1,RBFOX2,RPL7A,GRAP2,HEY2,SF3B5,POLR2C,NDUFB8,DCTPP1,RPS3,DSN1,JUP,MRPL17,SMCHD1,AGA,BIRC5,EIF4A3,KLF3,CTSK,PSMD10,THOC1,YIPF5,ZNF609,MNAT1,AKR1B1,EIF3E,CCND3,DCP2,DKC1,CREB3L4,GJC1,CXXC5,PAOX,HDHD3,SIRT7,NAA50,TFDP2,ABHD16B,STAT5A,MACROD1,GIT2,RPS29,RNF126,IFI35,FZR1,PSMD6,TRIM24,CDK1,RFXANK,EGR2,SNAPC3,MTAP,SMARCE1,SSBP1,SAP30,CLIC4,KLC2,MRPS11,CD63,THOC3,DPPA2,PPM1D,MPIG6B,ATPAF2,CGRRF1,LSM8,RALYL,ANAPC15,POLR3H,DRG2,PPT1,TCEA1,COMMD3,STAC3,CDCA7L,XPO5,RIMOC1,S100A11,AP5S1,INPP4A,SOD1,STK16,FOXP3,RPL35,NUP62,PRPF4,IMP4,PPIG,IRF1,MPV17L2,NICN1,GLO1,RBMX2,TIMM8A,ZMYND11,FOXC2,RNF8,MED4,KRT8,DNAJC10,TNFSF13,MRPL40,SNRPN,FAAP100,CACYBP,RPS9,MED29,TAF2,PABPC5,BECN1,CMKLR2,MED30,MSH6,MXI1,MAGEC2,COL3A1,WBP2,API5,TBK1,FBXO11,THAP2,ODAM,TCOF1,SPMIP6,RPS14,UBE2D3,SNRPD2,ZBTB18,NUDT19,ISCA2,MCMBP,MED27,PSPC1,ZBTB26,RING1,FAM76B,SUFU,SGF29,RNF14,RPA2,APOBEC3B,MED23,MTX2,CPSF4,APEX2,LIMD2,CTDSP2,SNAPC2,SPC24,DBR1,EGR1,E2F4,POLR2F,LSM2,PCCB,PDE9A,ESD,UTP25,IRF7,VEGFC,LDB2,SRSF4,MCL1,TRIP4,SRPK2,DENND2D,IQSEC1,FBXO7,CDC37L1,CTNNB1,TXNRD1,RNF187,DUSP10,CXXC1,SNAP23,NCBP2,CCNH,NR4A2,MORC4,DUSP21,CENPM,PGAM1,ASCC1,GEMIN8,PTPN5,RPS20,ISCU,H3C1,CTDSPL2,PDP2,TRIM8,MED13L,TP53,SUMO2,SLA2,KLHL7,CTSC,HLF,RPL23A,HMGA1,NUDT12,COPS7A,F2,RBBP7,E2F6,NUP50,PPIH,NUDT1,ROCK1,UBE2I,PHC1,ZBTB38,BTBD10,TCF21,PIP5K1A,PYDC2,OSGEP,ELP3,POLR1D,CHI3L1,MBD5,DHX9,HAX1,RPA3,MAD2L1BP,SKIC8,TMSB4X,ANP32A,CTBP1,NDUFS3,TENT5C,CCDC106,TRIM6,GLE1,NR1I3,ZNF692,CDK5R1,KLF4,CLP1,PRMT5,HMGB1,RPS15,APBB3,COX17,ZC3H14,DDRGK1,BARX2,PDHA1,EIF4E,FMO1,TAF7,CREB1,NDUFB7,ADRM1,USP39,FGL2,IK,DTL,EIF1AD,ZCCHC7,RPL27,SRSF7,IDE,RRP7A,TAPT1,ILF2,TAF5L,IRF2BP1,ZC3H11A,MRPS18B,FAM193B,SRSF8,THAP1,FGF1,TRAF7,PSME2,HBA1,YPEL4,MED11,COA4,RIOK2,FAM222B,MZB1,SUCLG2,BNIP3L,SMUG1,POLR1H,ARHGAP15,FHIT,CBR4,RPS26,PYCARD,TRA2A,MEF2C,BOLA3,PAFAH1B2,SRP14,MRPL34,CCNB1,DBH,KIN,FOXP1,NUFIP2,FBXO3,SKAP2,EIF2AK2,DXO,FMOD,PQBP1,PDIA3,RAPGEF5,MTHFD2L,TGFB3,TNFAIP8,NGB,TRIM27,MRPL47,NEK7,MPHOSPH6,RAB5A,ELOF1,TIMM17A,CCT2,UBE2L3,DYRK1B,NGRN,PPWD1,AMELX,PSMC3,HIRA,NOVA1,KANSL3,TERC,SCNM1,SMAD2,MYBL2,DHX38,AIPL1,BAG3,LSM4,PPARA,APOBEC3H,EGLN3,MBD3,RPSA,PPP1R26,PSMB1,UTP23,CCAR2,RBM42,LIPA,ATP5F1E,JADE1,F7,NEK2,UQCRC2,NAA35,JAML,PPP1CC,JUNB,HEXB,RETREG1,HNF1B,CDC7,CACNB4,NAA15,FAF2,SCG3,DLX1,MIF,MRPL36,SUPT7L,BACE1,POLD4,PML,PSMB4,TMUB1,KARS1,LRIF1,FERMT2,SPON1,SMAD9,TOR3A,CBX3,THOC6,RFX5,ZNF687,TOPBP1,KRR1,ABCE1,SPRN,MRPL57,FOS,GSTP1,HEXIM1,AMT,AATF,ERLEC1,MAPK10,HNRNPAB,PWP2,PHB2,RPL3,GTF3C3,SAP30BP,ARPC2,IRF3,MTG2,TMA16,HADH,SETD5,PNP,NCAPG2,PHF23,POLR2B,RXRG,PMPCA,GCA,SP2,CBR3,HEBP2,TWNK,H2BC17,FTSJ3,NFKBIL1,TNFAIP6,PSMD4,PSMD1,RPS4X,TRMT61A,CPSF2,RAB32,MRPL33,HYPK,GIMAP2,SNRPA1,POLR3B,PSMA2,DUSP26,IPO8,ATP5F1A,MAD2L2,TMT1A,RADX,STAR,CDC23,RSAD2,TNRC6C,DRG1,PRDX3,NONO,EDF1,CUL2,TRIM22,RFC2,NXT1,METTL15,MRPS18C,INO80C,ACSS2,MDC1,HOXB8,TIMM8B,FRMD8,ZNF22,CAB39,NEDD8,PHF13,GTF2F1,CEBPG,EXOSC3,NFE2L2,NPC2,EEF1A1,ZNF451,RUVBL1,CHTOP,TUBB,IGF1,RBM3,TMEM179B,CDKL2,CDKN2D,OLA1,MXD1,CCAR1,PGA4,CDC26,POLE4,GFM2,ING2,AGER,AKAP8L,PGM1,MYO6,CDKN2AIP,EYA3,HSP90AA1,IDH1,ID4,TRAPPC1,BRD9,RPS11,CTNNBL1,RFC4,MSX2,FOXN2,GON7,SELENOP,PTPN4,EHBP1,CEP85,SLC39A7,HFE,SNRPE,BAP1,MED17,TFB1M,ACP6,ARG2,PRPF19,MRPS26,TWIST2,FXN,AMACR,MAP2K3,CHID1,CHMP1B,OLR1,ISG15,SPTAN1,RLIM,ZBTB16,B2M,ELOC,PROX1,SYVN1,NEU1,CCR2,H2BC11,RUVBL2,SIAH2,CTSA,LDOC1,PTPN11,CWC15,ANAPC11,CHAMP1,PSMB6,USP15,UBB,SPOP,DPY30,CCT8,TAF10,ETFB,PYM1,SMAD1,PHF1,MIOS,TGFB1I1,BTG1,PAPOLA,ABHD17A,RPS27A,CLPX,PTEN,ZNF473,TAB2,PPP1R12A,PGR,ATF1,LSM5,NFYA,SERPIND1,GTF2H2,HNRNPD,SHOC2,AFTPH,PPME1,RPS2,RPL4,ZNF622,ZMYM2,RAD23B,TOP1,COL1A2,NDUFB5,HDAC5,CTSD,ALB,METTL14,RERG,ACADSB,VTA1,TSNAX,ISG20,AUH,EID2,GTF3C4,TIMM10,DNAJB4,UHMK1,PDSS2,FCF1,ADK,AGK,MGMT,MAF1,GPC4,PLAGL1,NAB2,CDK9,TESK2,FKBP14,ACACA,HTRA2,SERPINB10,SGMS2,UBE2N,YPEL5,POMT2,SUMO1,EP300,CHST2,MCOLN1,ZNF326,SF3B1,CNOT2,BUD23,STAP1,PSMC4,CSTB,ABITRAM,RPS6KA4,HNRNPL,HILPDA,EXTL2,NUP153,GALC,RBM22,NDUFS2,ZBTB39,GLRX5,HRAS,PPM1B,EMG1,PRDM4,CSH1,TIMM23,HOXB1,SYCE3,RPS5,PDHB,HBP1,PSKH1,GANAB,CNPY3,NXT2,INTS10,RBM18,PEG10,RPS17,PADI2,NUDT9,TIMP3,IL12A,RCHY1,ENY2,KLF9,CREB3,POLR2D,RAN,CBX5,SUPT5H,TRA2B,BCCIP,BANF1,LDB1,ETFA,TXNL4A,HNRNPA0,CNOT7,PCK2,ATP6V1D,ELK4,SELENOF,KMT5B,UBE2V2,SNRPA,LMNB1,HSPB8,MCM3,PRPF31,DBT,RNF7,LYZ,MYCT1,DNTTIP1,WNT7A,CTSB,PDIA6,COP1,ZNF175,SF3B4,MITF,MRPL49,CYP27A1,XPOT,PMM2,DNAJB6,CFL2,H2AC6,CAPG,COX10,APOBEC3A,C1D,POLR2I,CCND1,CCDC22,MRPL12,SETD3,TESC,F9,PCBD1,ABCF1,GGPS1,RPAIN,FAHD1,ALKBH4,GFM1,MRPL11,CMTR1,MED10,H1-5,RPP25,CHPF,TIMM29,PSMC1,PPARG,BHLHE40,RBBP9,PRKD3,UBE2D1,DLAT,GFI1,MYRF,RPS7,KPNA6,SHC1,FBXL4,PRDX4,PLA2G15,OARD1,H2AZ1,TADA3,AIP,PAGR1,PPIL4,SPTBN1,CD274,DLST,PRCC,RPF1,PSMD14,RBM5,UBL4A,DYRK1A,EVA1A,RPRD1A,MRTO4,PPM1K,SMAP2,SMURF1,MRPS33,DCTN3,MRPS7,GATAD1,MRPS17,ZNF436,HDAC11,FYTTD1,PAX9,RPRD1B,GTF2A1,ZBTB45,RERE,NOL12,HNMT,FEM1C,H1-1,VEGFA,GOSR2,COTL1,FOXD3,RMI2,NAA11,DNAJC7,TP53INP2,IFI16,EEF2,TFPT,CCDC174,HNRNPDL,MEF2A,RMI1,TUBG1,HCFC2,GTF2IRD1,UBE2S,SUB1,GCHFR,CAMK2G,PHB1,TSEN34,SERTAD2,MMUT,GPC1,DNAJC2,TEX264,FTL,ISG20L2,CD2BP2,SLU7,RNF113A,CD2,CIART,FBXW7,DDX39B,NSG1,ADH1A,CNDP2,CPEB1,ADD1,ARL4D,MRPL53,RBM7,NR2F6,ZBTB33,ATXN1L,PPP4C,CASC3,PRMT6,KPNA1,MAEA,SOX3,UQCC2,NOP9,STXBP1,ZHX1,PSMA4,SKP1,MYC,ZBED1,MACROH2A1,COMMD5,ETFBKMT,LDHAL6B,CGAS,POP5,DCUN1D1,RACGAP1,MED31,NKRF,SMC4,UPF3B,THAP7,TRIM34,FSTL1,MRPL51,CRTC2,F10,STAT1,MMP9,DCLRE1C,RGS10,ETV6,SELENOM,SIX5,GTF2E1,DNAJC8,SLC25A5,NRBF2,TOR4A,TAF1D,ASF1A,ACTB,PYROXD2,WDR20,ZNF24,IRF9,AQP3,SLPI,PPTC7,ZNF207,PPP1R8,PIR,P4HA2,PRPF18,CDK6,PHYH,TAX1BP3,GDI2,OSBP,PHF12,PDE12,RPL13A,MORC2,MRPS23,RBPJ,HSCB,TFE3,RARRES2,MTERF2,DEK,SMU1,HR,PSMB2,SLC25A10,MED22,ALKBH5,RGCC,RTCB,EIF2D,H2BC9,PDLIM4,HSPA5,XRCC5,SDCBP,FOSL2,E4F1,SRSF10,DCAF16,EZH2,GTF2H5,FURIN,HSP90AB1,ARL14EP,ERO1A,TREML1,CAND1,FUBP3,TLE1,CDC20,LMO2,GHRL,WDR82,CBX7,EID2B,CCNA2,PRIM2,NABP1,PYCR1,PRL,RPGRIP1L,HP,TIMM13,MDM2,NUDT7,NR0B1,RPL23,AURKAIP1,UBE2W,GCFC2,POLR1B,UQCC3,FGR,TULP3 |
| 3.689e-10 | -21.72 | PSMD12 (proteasome 26S subunit, non-ATPase 12) | protein interactions | 5718 | 313 | 139 | 19454 | 5460 |
SIRT7,DVL2,BAP1,RPA3,SQSTM1,DESI1,HSPA5,UBA52,PSMC4,UBLCP1,CFTR,PAAF1,CDC42,MRPL10,METTL14,GRM2,RPA2,HECTD1,UBE2M,HEXIM1,PSMA6,CCNF,SGTA,MSN,PSMC5,ADRM1,COPE,VIRMA,PTPN11,CARS1,PSMB2,AR,DNAJC5,USP14,MAPRE1,UBE2H,ATP1A1,PSME1,MAP1B,RAB1A,HSD17B10,NLRP9,HAPSTR1,PSMA5,HUWE1,SEM1,CAMK2G,EIF3E,CAPZA1,FKBP8,MRPL22,SOCS2,MEPCE,INSIG2,PSMB9,TMEM31,CAMK1,PSMC3,ZFAND2A,RAD23B,CD274,PSMB1,PRNP,FZR1,CDC5L,CAV1,COPS5,ZFAND2B,PSMD7,CCDC92,MAP4,USP15,RFC4,PSMA3,AKAP1,TXNL1,NSFL1C,HNRNPA0,UFL1,ITGAV,RNF11,DDI1,PSMC1,PAFAH1B1,PSMB3,RND2,PSMB7,EIF3K,PSMD6,TUBB,RPL35,PSMD4,PSMB6,PSMA4,CDKN3,ALDH1L1,COPS7A,BAG3,PSMD1,BTF3,PSMD14,BRCA1,MED10,LAMTOR1,RIT1,TRIM11,UBE3A,PSMA1,KRAS,PSMA2,HNRNPF,AHCYL1,RPS27A,PSMD12,TXNRD1,NAA16,NAA15,PPP2R1A,SOX2,PPID,KDELR1,PLS3,EZH2,MOB3C,FBXO32,PSMB5,PSMB4,WDR6,PSME2,RHOH,HSP90AB1,PSMD3,IFI16,EIF3D,STK4,ATG7,AGR2,PSMD10,TRAF6 |
| 3.689e-10 | -21.72 | FGB (fibrinogen beta chain) | protein interactions | 2244 | 188 | 93 | 19454 | 5460 |
TES,PRNP,TMPO,CALR,SCGB1D1,HP,NME2,KIAA1143,AGPAT1,EGFL8,RING1,CTNNBL1,TF,VRK1,SMN1,MINDY3,SERPINA1,PDE6D,RNF181,CAB39,CSNK2B,HPF1,SNX3,DUSP3,CSK,NAA50,PTPN11,ASCC1,CHORDC1,SLC6A1,PNPO,MIS12,TCEA1,CLU,SF3A1,ARHGAP1,DDAH1,SPR,EIF3J,UBLCP1,CFTR,RPRD1B,H2BC11,CHMP1A,STX17,OXSR1,RPRD1A,PSME2,TMEM237,VPS26A,BTF3L4,ASB7,DDX1,XPNPEP1,TRIM37,GNL1,GCA,SAR1B,FEN1,NAA15,ARFGAP1,RBM12,SOX2,SERPINA3,KIF2A,PIR,PPID,CCR1,SERPINA5,GNAQ,GTF2F1,LGALS3,FBXO22,ESR2,TBCE,PAPOLA,PIK3R3,HMGCS1,ADK,ATG3,CYP3A43,ARMT1,PYM1,TBC1D24,ATPAF2,UFL1,PYGB,SSBP2,CDKN1A,ETF1,PAK2,MAP2K1,ANXA7 |
| 3.718e-10 | -21.71 | UBR5 (ubiquitin protein ligase E3 component n-recognin 5) | protein interactions | 51366 | 494 | 202 | 19454 | 5460 |
ZNF622,MAGOHB,UBE2L3,PRSS37,VIRMA,CCNF,ENO1,EIF4A3,GSK3A,ECRG4,TXNIP,SMAD2,PAIP2,CDC73,FBXO7,PPP1CC,NONO,AR,EIF5B,PDHB,NHP2,RPA3,SIRT7,TCEA1,CDK1,METTL14,ZCCHC17,WTAP,PRMT2,TOP1,AKAP17A,PTP4A3,CDK9,TOPBP1,SEM1,DNAJC30,MDC1,ABHD10,MSH6,RIGI,EHD4,RING1,MRFAP1,PC,UBE2B,EEF1A1,MTM1,RPL35,TUBB,MAD2L1,OTUD6A,CPSF1,SNRPD2,SNRPD1,RPS9,PSKH1,BRCA1,DCAF4,NLRP3,ILK,HTRA2,DSN1,CUL3,CFAP20,DUSP26,BIRC2,TERT,PPARG,SLC25A3,MYL6,PGRMC1,NRDE2,CDKN1A,SPTAN1,SRSF10,EGLN3,DHX15,RPL8,ARL11,PHB1,IGBP1,UBE2D1,RHOG,DDX23,MED4,PIK3R1,DPY30,MARCHF5,TRA2A,ZNF207,TRIM37,UBE2A,SRSF4,RPS27A,SSRP1,TOB2,IMMP2L,SLC25A5,PPAN,ARGLU1,PCNA,TESK2,UBE3A,RPS11,SNRPE,FAF2,ACTN4,RPL29,TULP3,GTF2E2,ERLIN2,BUB3,NR1I2,CDC20,UQCRC2,MOB4,F9,UHMK1,ZBTB38,AP3S2,UBE2H,AKT1,PSMB2,SUB1,KDM1A,HSPA5,DDX46,BAP1,PML,NBN,PGK1,RNF113A,RPA2,DYRK2,TFIP11,UTP15,LUC7L3,SPTBN1,GABRA1,SNRNP27,CFTR,FZR1,MIF,DKC1,CDC5L,COQ8A,TUBG1,H2AC4,CDK12,KPNA1,RPS2,PPIL4,TMEM33,KPNA2,TOLLIP,STX11,CAPZA1,SLC25A11,MRPS18B,SLC16A1,SURF4,DISC1,TAF2,TP53,ACTR1A,MATR3,SNRNP40,LMBR1L,SMU1,PHF21A,GTF2F2,H2AZ2,FBXW11,COP1,MYC,SRSF2,UBE2D3,EEF1G,EYA3,SAP18,DDX39B,TPD52L1,PAIP1,PGR,TCP1,SRSF1,POU5F1,PTDSS1,XPO1,CTNNB1,SATB1,POLDIP3,PABPC1,RUVBL2,HDAC11,CAAP1,PNMA2,MOB3C,RANBP1,SUPT5H,SOX2,KIF2A |
| 3.739e-10 | -21.71 | REEP5 (receptor accessory protein 5) | protein interactions | 7905 | 361 | 156 | 19454 | 5460 |
SNX1,HNRNPL,TMEM170A,TMEM97,RAB35,CYB5A,STX5,MAGED2,KDM2A,FAM241B,CDK5RAP3,YWHAB,TMEM208,RPL6,DDRGK1,FAM241A,EMC6,NUP42,EMC8,KLRF1,RETREG1,TSPAN11,RINT1,PLSCR1,RPL31,SLC2A8,RPN1,STIM1,MACO1,ARFGAP1,STBD1,FAF2,MED17,REEP4,RBBP4,CAVIN2,APEX1,ATP6AP2,POLR2B,MOG,CYB5R3,RPS9,RETREG3,LMNB1,VMP1,MCAT,CNIH4,SCFD1,VEZT,KDSR,RER1,UFL1,COIL,ATP5MK,TSPAN15,PEBP1,TMEM160,IMPACT,SLC35F2,AKAP1,TMEM185A,HSPA8,RABAC1,UBAC2,VAPB,FAM3C,PSRC1,TOR1AIP2,PGRMC1,NUDT3,TMUB2,SEC62,OTULINL,YIPF5,DERL2,ARL6IP5,DNAJC1,TMPO,LMAN1,CAMLG,SRPRA,HACD3,PTPN1,CDCA3,HSD17B11,ESYT1,TM4SF18,POR,OSBPL8,DHRS7,TMEM199,EI24,LAMP3,HM13,THRAP3,SRPRB,RAB3B,TMEM33,RIGI,GALNT2,FKBP8,TCOF1,NSDHL,YIF1A,STX18,ABHD4,CCDC47,PREB,GDE1,ZMYM3,LBR,COPE,SEC63,SH3BGRL,UBB,STUM,ATL1,CHRM5,SCAMP2,PLP1,ODR4,PHAX,SAYSD1,SMPD2,ATP1B3,REEP6,MORF4L1,GORASP2,HMOX2,DNAJC8,LPAR1,TMEM167B,LITAF,YKT6,TMEM209,RGS2,RETREG2,TEX264,RPA3,RTN4,DERL1,MTDH,VIPR1,SLC12A2,SSR1,SYS1,GOLGA5,USE1,GALNT1,RPA2,LEMD3,ARHGAP1,SEC22B,ATP6V0E1,RABL3,GTF2H4 |
| 3.742e-10 | -21.71 | GTF2E2 (general transcription factor IIE subunit 2) | protein interactions | 2961 | 175 | 88 | 19454 | 5460 |
PTPN11,GMPS,CHORDC1,SNX5,ZNF330,CYRIB,CAB39,GTF2A1,CSTF3,DUSP3,SF3A1,PPP1R8,CCNH,UBLCP1,CDK7,EIF3J,SPRYD4,PRKCA,PML,TCEA1,EIF5B,FBXW7,OIP5,UGP2,MOV10,GRSF1,ERCC3,GTF2E1,LRRC40,GTF2B,ARL4D,TOP1,MDM2,TP53,GNG10,CDK8,GINS4,CBX3,DNAJC2,POLR2G,PPME1,H3C1,VRK1,RNF20,MNAT1,MDC1,EXOC8,PDF,RIT1,ZMPSTE24,EFHD2,CMTR1,GTF2F1,GTF2F2,POLR2B,APEX1,NUP62,ETF1,PYM1,FOS,EEF1G,LZTFL1,RP2,GINS3,STX7,TAF7,HNRNPA1,DDX23,PDCD10,SIN3A,RPRD1A,DNM2,PBDC1,GATD3,HSP90AB1,RAF1,RBM12,LYPLA1,NAA15,FEN1,JUN,GTF2E2,MTA2,POLR2C,ZRANB2,SART3,PICK1,KRAS |
| 3.863e-10 | -21.67 | LAMP2 (lysosomal associated membrane protein 2) | protein interactions | 3920 | 580 | 231 | 19454 | 5460 |
FAM83B,APLNR,TAX1BP1,TAMM41,RALGAPA2,SLC30A5,TMEM38B,MYC,CREBBP,THOC6,SLC38A1,LAMTOR1,RAP2A,EP300,STK26,HSPA8,TMEM106B,GOSR1,BORCS6,C2CD4C,STX5,VAMP7,TMEM97,SNRPA1,RAB1B,DDRGK1,PPFIBP1,SLC38A9,SLC38A7,TSPAN10,PTDSS1,LAMP2,EFNB1,EWSR1,TMEM87A,RAB18,VAMP8,SLC20A2,ROCK2,SOX2,SNAPIN,NCSTN,ARFGEF1,PTPMT1,STX10,SF3B6,SRC,ROCK1,DAPK1,RALA,GORASP2,KCNQ5,SUB1,RAB2A,C9orf72,NDUFAF2,SNX5,UBE2H,ATP1A1,ARFIP1,RAB9A,TEX264,PIP4P1,SPTBN1,LEMD3,CSNK1G3,VPS54,BORCS5,ATP8A1,SLC39A10,CAMLG,RAB39B,LMAN1,TMPO,STX6,SLC38A2,FCHO2,VTI1B,DNAJC1,FZR1,MIOS,EDEM1,DHRS7,TUBG1,RAB13,SLC6A8,RAB3B,SRPRB,AKAP12,UBIAD1,GTPBP8,TP53,RAP1A,SNAP29,SPRY1,TFRC,TFCP2,GPR89A,AP2M1,SLC30A7,ARF1,FAM91A1,CHCHD3,TUBB,RBBP4,LGALS3,RHEB,MAP3K21,RAB11A,NIBAN2,MTG2,VEZT,VMP1,SCFD1,WDR20,LMNB1,MYO6,TAFAZZIN,BET1L,NUBP2,SLC35F2,STX7,HSCB,RAB6A,EHD1,PGRMC1,NOTCH2,VPS18,VAPB,HP1BP3,GJA1,TSG101,WDR6,PRKCQ,SNX1,HYPK,MPP1,SNX2,OCRL,WDR11,PRPF19,PLCB1,JAK1,PCNA,SCYL2,OSTM1,AP1M1,TNF,FAF2,RAF1,MARCKSL1,MACO1,OTULIN,STX12,CTSA,VPS33A,VAMP2,EZH2,STIM1,RPN1,MSN,SNX12,SLC11A2,SCAMP2,SMAP2,TUBA1B,VAMP3,FERMT2,SNX3,YES1,RAB14,HMOX2,DEPDC1B,EPHA2,AP2A1,PPTC7,LGALS8,SQSTM1,HELLS,ATG4C,TMEM209,NF2,CERS2,YKT6,SLC7A1,CNP,ARHGAP1,PIP5K1A,SEC22B,RABL3,STOM,PICALM,GOLGA5,SLC12A2,CTDSP1,AP1AR,PTP4A2,CDCA3,EEF1AKMT3,PTPN1,SRP14,SRPRA,CAV1,FAM118B,MDM2,ARF6,RAB23,EI24,RELL1,ORC5,TMEM199,OSBPL8,ESYT1,TMEM184C,SLC2A1,SNAP23,SEPTIN7,DLG1,RAB1A,STX8,NSDHL,CTNND1,SOCS2,SFT2D2,AGPAT5,MAP1LC3B,LBR,SLC29A1,CCDC47,APEH,VAC14 |
| 3.943e-10 | -21.65 | cytosolic large ribosomal subunit | cellular component | GO:0022625 | 54 | 38 | 19108 | 5553 |
RPL13A,RPL28,RPL26L1,RPL23A,RPLP2,RPL7,RPL23,RPL19,RPL35A,RPL9,RPL17,RPLP1,RPL7L1,RPL26,RPL39,RPL24,RPL12,ZCCHC17,RPL10A,RPL22,RPL7A,RPL4,RPL27A,RPL15,RPL27,RPL32,RPL3,RPL18,RPL35,RPLP0,RPL37A,RPL31,RPL10L,RPL29,RPL6,RPL10,RPL8,UBA52 |
| 3.948e-10 | -21.65 | DDX3X (DEAD-box helicase 3 X-linked) | protein interactions | 1654 | 607 | 240 | 19454 | 5460 |
LMNA,JUP,PICALM,RARS1,RPS14,MIR1-2,CDK7,EIF3J,GTF2I,RPL4,FBXW7,MIR7-3,PIK3R2,MBD3,PIAS1,INPPL1,RPA3,MIR205,KIN,MIRLET7I,MIR34C,MAVS,SQSTM1,MIR145,AP2A1,CTSD,PYCR2,RUNX1,USP14,PPP1CC,GMPS,AR,NDN,VIRMA,MIR16-1,ENO1,EIF4A3,GSK3A,RPS20,ALB,RPS12,MIR17,MIR20A,ILF2,SRP72,FBP1,YTHDF2,MIR200C,MIR15A,VRK1,EIF3E,MIR34A,NFKB1,HDAC6,DCUN1D1,CDK9,SMAD3,MIR106B,AIFM1,ACTA2,MIR25,LARP4B,PPP1CB,HSCB,UCHL3,YTHDF1,MIR106A,G3BP2,HADHA,RPS5,MIR363,SP1,ILK,RIT1,LSM14B,CUL3,CUL2,MIR98,EIF4A2,DYNLL1,MIRLET7D,PRRC2A,EIF3K,AP2M1,RPS9,EZH2,RPS11,ZNF263,B3GNT2,GFPT1,LGR4,G3BP1,TNF,RPS27A,SAR1B,RAD21,TRIP4,SKIC8,TRAF6,AHSA1,LYZ,MIR1-1,PPP2R5A,HNRNPA1,EIF3D,PPIA,DHX15,PHB1,MIR7-2,MIR141,RPA2,HEXIM1,MIR21,MIR7-1,MIR34B,CFTR,MAEL,RPS15,ZC3H15,MIR29A,MIR107,HSPA5,MIR10B,BAP1,PML,IRF3,RNF113A,SPOP,EIF3G,BICD2,RC3H2,LACRT,TRIM23,IGF2BP1,ATP1A1,UBE2H,RPS17,SRPK2,RPS3,PSPC1,TFCP2,NUPR1,RPSA,TP53,KDM4B,NEDD8,MEPCE,MIRLET7C,MIR16-2,MIR200A,MIR9-3,SNRNP70,RPS2,USP15,CD81,CSNK2A1,COPS5,API5,RPS16,CAND1,FZR1,MIRLET7G,MIR429,TMPO,MBD5,CD274,SYNCRIP,ALYREF,CD4,MAP2K1,PPT1,EIF4B,PIH1D1,NUP62,MTF1,UFL1,FXR2,STAU1,SAP18,CD40,SNRPA,RPS28,HSPA8,HDAC5,EP300,DDX5,LCN1,FBXW11,ICAM1,CREBBP,MYC,BTF3,MATR3,APEX1,NFKBIA,CMTR1,NFKBIB,PRMT5,MIRLET7B,MTA2,RPS23,TOP3B,SOX2,MIR222,ISG15,RPS7,KRAS,MIR155,CBLL1,HNRNPDL,LSM14A,MIR9-2,MIR206,EWSR1,RTCB,AGR2,MIR31,DDX1,MIR221,MIR140,MAGOH,IFI16,WWP2,RPL6,MIR143,YWHAH,MIR29C,YWHAG,XPO1,CTNNB1,DDRGK1,FAM98A,RPS10,SUMO2,MIR9-1,FABP5,FUBP3,MAGED2,EED,MIR214 |
| 3.988e-10 | -21.64 | SART1 (spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP) | protein interactions | 9092 | 291 | 131 | 19454 | 5460 |
FBXW7,SMC4,HSPA5,PRPF4,PML,SIRT7,RPA3,RNF113A,SQSTM1,RPA2,TOX4,ACACA,LUC7L3,HEXIM1,TFIP11,SEC22B,SNRPN,SF3A1,SRPK2,PPP1R10,EZH1,CTTN,EIF4A3,SF3B6,PSPC1,UBE2I,GSK3A,TRAPPC14,LSM6,TXNIP,MECP2,UBE2H,ZBTB38,RPL7A,SUB1,AR,NONO,KPNA2,THRAP3,CAMKV,LSM4,SNRPG,MEPCE,DHX9,RPL23A,DDX42,NUPR1,TAF2,PSMC3,TP53,RPSA,PHF23,EEF1A1,CD2BP2,H2AX,TOP1,FZR1,CDC5L,SURF6,RBM42,CDK9,ARL4D,SNRNP70,H2AC4,BRD3,LSM3,TRAPPC4,RBM17,MPG,PPIL4,STAU1,UFL1,ARL6,SAP18,UPF3B,DDX39B,SNRPA,DDX5,SF3B1,PCLAF,USP39,TRMT112,MFAP1,NUFIP2,TIMM10,FBXO22,PSMD6,ZCCHC7,SNRNP40,SNRPB2,SNRPD2,RPL37A,PRMT5,SNRPD1,FTSJ3,RCL1,CUL3,HNRNPC,MYC,SNRPB,PSMD1,PRPF31,SSRP1,PSMD12,SRSF4,PABPC1,SRSF7,FAM76B,SNRPE,E2F4,SUPT5H,UBL5,NCSTN,PPP2R1A,LSM5,SUMO2,SNRPD3,SNRPA1,NOP58,PHB1,SRSF1,TRAPPC10,WDR82,DDX23,NDC80,WWP2,ZCCHC10,IFI16,PRPF19,PSMD3,DDRGK1 |
| 4.041e-10 | -21.63 | PDCL (phosducin like) | protein interactions | 5082 | 127 | 69 | 19454 | 5460 |
GNB1,PRDX2,POLR3H,SEC61B,RMDN3,PSMC5,GSK3A,GNG12,FIS1,RAP2C,CCT2,RAB11A,KLHDC8A,GNB4,PXMP2,PHB2,PPP2R2C,NF2,DERL1,MAVS,AKAP1,SYVN1,EXD2,FBXW4,SSR1,SAMM50,ST7,SEC62,MTX2,ACTL6A,CCT7,TMPO,EGLN3,DYNC1I2,TCP1,FZR1,DNAJC1,HSD17B11,GNB3,SYNCRIP,PTPN1,HNRNPD,SUV39H1,ACTR3B,HNRNPA1,XPO1,ATG7,GNG2,GNG11,YWHAH,SLC25A46,FKBP8,RAB3B,KRAS,GNG5,TMT1A,CCT8,CYP2C9,MMACHC,RPN1,STIM1,GNG10,TULP3,GNG3,RPAP2,MAP1LC3B,CCT5,MRPL11,MTCH2 |
| 4.042e-10 | -21.63 | RPL18A (ribosomal protein L18a) | protein interactions | 6142 | 410 | 173 | 19454 | 5460 |
CUL3,NOP16,ZNF668,BRCA1,RPS5,RIT1,ARF1,ZNF22,RPL37A,SEC61B,RPS9,RPF1,RPL35,RPL19,EMC9,NOP53,COIL,G3BP2,MAP3K14,DICER1,RPL23,RPL8,FOLR1,RPL9,PHB1,RPLP1,RPLP2,NOP58,RPL7,B3GNT2,E2F4,JUN,EZH2,CHMP4C,RPS11,RPS24,TRIM37,RPS27A,SAR1B,PPP1CC,AR,DNAJC19,CCNF,PRKRA,PTEN,RPS20,RPS12,NDN,RPL13A,SH3BGRL,RPL22,RPS14,UBA52,PTP4A2,GRM2,METTL14,MAP3K12,RPL26L1,RPLP0,RPA3,SIRT7,KIN,MTDH,NF2,HMGB1,RPL4,FBXW7,BRIX1,GRSF1,HDAC6,MPHOSPH10,RPL12,RCHY1,RPL35A,CDK9,FBP1,EEF1A1,TAF1D,RPL15,SRP72,RPL23A,RNF115,PAK1IP1,VRK1,RPS13,MYC,BTF3,THAP7,FTSJ3,RPS26,COP1,H1-1,NSA2,CMTR1,RPL10,RPL27A,MTF1,PIH1D1,HSPA8,SF3B1,RAB5A,UFL1,STAU1,DDX50,WWP2,RPL6,RIOX2,XPO1,CTNNB1,NGDN,DDRGK1,SRSF1,EED,RPS10,LYAR,TRMT1L,MAGEB10,SOX2,RPS7,RPS23,RPL18,RPL31,BCL7B,PABPC1,KRAS,RPS4X,RPL28,RPL7A,SUB1,RC3H2,TRIM23,UBE2H,RRP7A,RPS3,RPL10L,SRPK2,CFTR,RPA2,WWP1,ZNF770,KLF4,RPL27,BAP1,PML,EXOSC4,RNF113A,RPS15,ENY2,COPS5,TUBG1,SNRNP70,RPL24,NOL12,RPS2,RPL10A,USP15,RPL32,RPS16,CAND1,FZR1,DKC1,RBM42,SURF6,UBL4A,TP53,RPSA,DNAJC2,CAPZA2,RBM34,RPL3,IMP4,MEPCE,RPL17 |
| 4.118e-10 | -21.61 | SNW1 (SNW domain containing 1) | protein interactions | 22938 | 731 | 281 | 19454 | 5460 |
SIN3A,SRSF1,MAGED2,PGR,SUMO2,TCP1,SNRPD3,SNRPA1,PEG10,HSP90AB1,CCT7,GSTM3,ZCCHC10,DDRGK1,EXOC1,DDX1,CDC23,HSPB1,MAGOH,DRG1,RINT1,PABPC1,CCT8,RUVBL2,PICK1,RTCB,HNRNPF,KRAS,RUVBL1,ROCK2,DHX38,NUP37,TUBB4B,HDAC11,KTI12,SF3B4,MATR3,ATP5F1B,SNRNP40,ESR2,MYC,HNRNPAB,HNRNPC,ZMAT3,PSMD1,BAG3,SNRPB,CPSF2,CCT2,FTSJ3,SLU7,DDX39B,SNRPA,RFC4,SPECC1L,SF3B1,HSPA8,EP300,DDX5,UFL1,TRA2B,HNRNPA0,PSENEN,SRSF2,STAU1,EEF1G,PAK2,CTBP1,SYNCRIP,UBE2N,CAND1,RBM42,TMPO,CDC5L,RBM17,API5,SMAD4,TUBG1,SMCHD1,SNRNP70,KPNA1,CDK12,SNIP1,TCEA2,DHX9,CDC40,H3C1,PSMA5,CSE1L,KPNA2,HNRNPK,CAPZA1,UBL4A,KBTBD4,TP53,ACTR1A,ESS2,EXOC3,DDX42,CBX3,IK,PSMC3,SF3B6,PSMC5,SRP54,BUB3,CSTF3,TRAF1,SMARCA5,VPS39,CCNB1,ANAPC15,EXOC5,CEP70,SPOP,NR0B1,BICD2,TRIM23,ELAVL2,CDKN2AIP,UBE2H,ORC6,DDX46,NBN,PML,CWF19L1,RBM22,EIF4E,HSPA5,SPTBN1,ZSCAN1,RPA2,TCP11L1,ZNF326,UBE2M,TFIP11,LUC7L3,DNM2,TRIM15,SPTAN1,KCTD10,BUD31,EGLN3,NUF2,DHX15,LRWD1,PRDX1,PSMD3,PRPF19,NDC80,BABAM1,BCL7C,HNRNPA1,DDX23,HNRNPD,SCYL2,HSPD1,HNRNPA2B1,BAG2,SRSF7,FHL3,RBBP7,TRIM37,PSMD12,SSRP1,RFC3,RAD21,RFC2,VDR,RAF1,FEN1,NUP153,PPP2R1A,EZH2,PRKAG1,RBPJ,OTULIN,SNRPE,TMEM14B,CPSF1,TRMT6,SNRPD2,TUBB,ACTB,SNRPB2,NIBAN2,CUL3,CUL2,RFC5,CAPG,FYTTD1,LMNB1,HSP90AA1,ILK,HTRA2,NKAPD1,TRUB1,NUP50,GNA14,MCMBP,ZDHHC17,PSMC1,UNC45A,G3BP2,PPP1CB,EHD1,VAV2,APOBEC3C,MFAP1,ARCN1,SMAD3,RB1,LDLR,THOC1,TOP1,CDK9,CWC15,ORC5,ERCC3,LRRC40,EXOC2,KIAA1143,DNAJC7,CLP1,EHD4,SEPTIN7,CTNNBL1,TSSC4,LSM4,VRK1,TRIM63,OLA1,SMN1,MSH6,SNRPG,CCT5,DDX39A,EEF1A1,MAP2K3,CD2BP2,EXOSC8,ACTR2,GABPB1,JCHAIN,SRP72,CCNF,EZH1,EIF4A3,TUBA1B,CTTN,GSK3A,MAGOHB,CSK,PPP1CC,RACGAP1,AR,NONO,SMAD2,CDC73,RPA3,HELLS,DVL2,SIRT7,PRPF4,HMGB1,SMC4,AATF,CPSF4,WDR83,SF3A1,PSMC4,TXNL4A,RBFOX2,CDK1,LMNA,TOX4,HSP90B1,PICALM,LSM2,OXSR1,SHOC2 |
| 4.156e-10 | -21.60 | establishment of localization in cell | biological process | GO:0051649 | 1619 | 587 | 18204 | 5365 |
CMTM6,GAS8,TRIM37,ATP6V1C1,TOMM22,WASL,ATP6V1G1,VAMP8,RAB1B,KXD1,EIF2D,PEX13,RABL3,HSBP1,NAPG,THOC3,AP5S1,VPS4B,SNX33,TIMM10,SLC31A1,C9orf72,ADRB2,RIMS4,SLC6A3,LCA5,STBD1,DPY30,KLHL12,CHP1,PPFIA2,OSBP,FGF10,SPC24,SEC22B,RAB29,CPT2,CPT1B,VTA1,BAG3,AP5M1,ARL5B,NDFIP1,CBL,TRAPPC3,BECN1,CBLN1,POLA2,NAPA,ATP1B1,RAB13,PICALM,RAB3A,DLG1,KIF1C,COPZ2,HPS6,CSE1L,MAD2L1,ACTN4,XPO5,OS9,AFTPH,CTBP1,HGS,RAB28,CHGA,COPS5,RNF126,SLC66A2,WDR11,RAP1B,RABL2B,SKA3,VIPAS39,RAB9A,YWHAH,RAB18,TRAPPC13,PSRC1,CCL3,NXT1,ATP6AP2,ATP6V1D,SYNDIG1,STX8,HSP90AA1,SLC48A1,CNIH4,MTCH2,STK3,CFL1,SNAP25,DNAJC19,CASK,ZNF207,TMEM50B,SEC61G,THOC2,CLBA1,RIMS3,HNRNPA1,PREPL,TOMM40,SLC6A2,SNCB,IFT172,GOSR2,ARFIP1,TUBA1B,FAF2,CDC42,SLU7,HSPB1,GOSR1,IFT22,OPHN1,ZMPSTE24,TNPO3,HSPA5,TRAM2,SNX3,IFT57,ALKBH5,UBE2I,AQP3,CCDC186,AP2A1,EGR2,MTM1,PSEN1,ATP6V1A,CAV1,CDR2L,STARD3NL,SMG5,FKBP1B,BLOC1S3,AGAP2,RAB1A,VTI1B,LCA5L,AP2M1,PLEKHF2,CAV3,CORO1C,SEC22A,RANGRF,ARL4D,RAB11B,VPS28,CTDSPL2,NSFL1C,STX1A,RAB6A,CDK5,TBC1D24,PREB,TRIM46,RHOB,PLEKHF1,TMEM50A,APPBP2,VAPB,POLDIP3,GRPEL2,ARMCX3,RAF1,PPT1,RANBP6,HRH3,SEC13,ANP32A,RAB2A,MRGPRX2,VAMP7,RAB6B,ERLEC1,RAB11A,TMEM106B,ING1,SEC61A1,GJA1,NEFL,CFTR,LMAN1,RAB9B,TBC1D17,EXOC3,TRAPPC10,TBC1D5,CASC3,ARF6,EXOC5,EXOC8,PLEKHA8,TIMM23,VAMP2,TOMM20,TBC1D13,PEX3,SPRN,HSP90B1,CDKN1A,CIDEB,BORCS8,ASIC2,PLEKHJ1,TRAPPC6A,RAB31,FBXW11,RSRC1,TBC1D10C,NUP35,CITED1,TRIM23,CTTN,RB1,STRADB,ANO3,TMEM87A,P2RY1,ARHGAP1,TRAM1,TMEM38B,LARGE1,CHMP1B,HSPA8,NETO1,RPAIN,ZBED3,TOMM70,TMED7,ARF4,NUP42,RPS15,TRIM27,PPFIA3,GNPTG,SKA2,BLOC1S2,BCS1L,STK4,ARF1,TP53,NOP9,MAP1S,KIF3B,SKA1,VPS4A,ARHGAP21,NCBP2,EHD1,TMED5,UFD1,CDKN1B,GLE1,STX12,MAPRE1,CHMP5,FYTTD1,ANKRD50,DESI1,LIPA,RBM15B,LIN7C,CHMP4C,SCFD1,ARCN1,CCDC22,BET1,RPL23,YIF1A,YIPF4,TRAK2,CLN8,AP1AR,SNX2,SLC6A4,PTGDS,SAMM50,KPNA2,SRP54,CDAN1,MKKS,MREG,FBXO22,RAB32,IPO8,LMNA,FAM53B,PEX26,SLC6A1,WNT7A,PPP3CA,AKT1,PHETA2,TMED4,VPS26A,VPS39,UBXN6,SELENOS,NFKBIA,ROMO1,SNX5,ENY2,SLC18B1,PDCD10,MAGOH,AP1M1,RAB5C,SNX18,NSG1,CALR,ATP6V1G2,CTNNB1,VPS26C,KDELR2,DYNC1I2,BAK1,MAP1B,SLC1A2,IFT25,ENKD1,FHIP1B,SNX12,BUB3,CCHCR1,TIMM8A,KIT,SEC61B,NUP153,NUP50,SOD1,SYNRG,LAT2,DDX39A,TFG,MIS12,STXBP1,MCPH1,TSG101,STX7,PCSK9,FAM91A1,RAMP3,TEX261,SYVN1,KPNA6,PRKCE,CPLX2,BCAP29,DERL1,SSX2IP,RAB27A,ABCE1,TUBA1A,TNPO2,VPS26B,VPS33A,LDLR,CPLX3,AP1S2,TMED1,AP1G2,MIA2,SPRY1,CLIP3,LMNB1,SNAP29,SNAP91,MAP4,MYO6,RAB23,THOC6,DYNC1I1,LRRTM1,DNAJC27,BORCS6,BBS5,ARL11,COPE,SLC6A12,KPNA1,ERP29,TRAF3IP2,SEC22C,BAX,EIF4E,LAMP2,AHCYL1,CEP19,CHMP1A,DDX39B,UBB,LEPROTL1,DNM2,EMP2,HDAC3,FAM53C,SMURF1,ILDR1,EXOC1,UBE2B,RHOBTB3,HM13,DSN1,EHD4,SYT4,SFN,TIMM17A,CACNG3,PPP1R10,TRAPPC1,CHMP2A,XPOT,PAX6,TSPAN18,TRAPPC6B,PEX5L,SAR1B,TIMM29,TXNIP,SLC32A1,SNAPIN,VPS18,CHMP2B,SRSF10,PRKAG1,SYN3,IREB2,TRAPPC3L,RINT1,SYK,CLU,SCG5,NUF2,DERL2,RAB14,LIN7B,FCHO2,HDAC6,TMED9,STX11,GRPEL1,STX16,SELENOT,ZC3H11A,UBAP1,XPO1,KCNJ10,CD63,SCYL2,CYBRD1,TMEM108,RILPL2,NUP37,ASIC1,EIF4A3,RAP1A,NPC2,GIT2,SEC63,YKT6,CLTRN,NXT2,TIMM13,SELENOK,STAR,LAMTOR1,SNAP23,SLC25A20,STX6,TSPO2,VPS16,RAB5A,NLGN2,USE1,NDP,YIPF5,RAB35,PICK1,VAMP3,TRMT10B,VPS54,RAB19,NHERF1,HCLS1,SLC11A2,SYP,SYBU,EHD3,EXOC2,ARL6,PML,NUP62,SRPRA,TUBB,TRAM1L1,TESK1,SSNA1,KCNJ8,DRD1,UBXN2B,TIMM8B,MGARP,CHTOP,NDE1,SLC25A46,CALY,PHB2,HIKESHI,TRAPPC2L,NECTIN2,HNRNPA2B1,PIK3CG,SLC6A11,STX18,SQSTM1,PAFAH1B1,IFT52,ARFGAP3,DYNLL1,STX5,SEC23A,CDC23,NLGN1,RAB22A,SNX10,NUP107,STX10,TMCC1,RAB8B,P2RY12,THOC1,GPIHBP1,ARL4A,SURF4,STAU1,ZFAND2B,SYT2,CHAMP1,TOM1,PHAX,MAGOHB,ALYREF,SNCG,WDR19,MTX2,ACAP2,PIK3R1,RAN,AGK,CUL3,SNX1,CPLX1,DNAJC5,TERB2,LYSET,YWHAZ,TIMM21,AP3S2,BORCS5,STARD4,STX17,TOMM7,RGP1,SNX11,CCNB1,BLOC1S5,CAMK1,BICD2,BET1L,TMED3,ACTR2,SEC62,SNX17,AP2S1,NDC80,MAIP1,TRAPPC4,KDELR1,CTSA,SEC61A2,BORCS7,TOMM6,SYS1 |
| 4.307e-10 | -21.57 | miRNA-mediated gene silencing by inhibition of translation | biological process | GO:0035278 | 99 | 59 | 18204 | 5365 |
MIR16-1,MIR210,MIR874,MIR10B,MIR29A,MIR29C,MIR28,MIR200C,MIRLET7I,MIR204,MIR181C,MIR125A,MIR298,MIR212,MIR221,MIR503,MIR218-1,MIR146A,MIR378A,MIR21,MIR96,MIR17,MIR214,MIR20A,MIR100,MIR181D,MIR208A,MIR31,EIF4E2,MIR106A,MIR148A,MIR145,MIR1-1,MIR126,TNRC6C,MIR379,MIR877,MIR15A,MIR9-1,MIR345,AGO1,MIR107,MIR135B,MIR346,MIR133B,MIR106B,MIR144,MIR24-1,MIR101-1,MIR590,MIR98,MIR148B,MIR939,MIR26B,MIR1271,MIR182,MIR205,MIR495,MIR132 |
| 4.318e-10 | -21.56 | macromolecule metabolic process | biological process | GO:0043170 | 5858 | 1904 | 18204 | 5365 |
WWP1,TAF2,ABHD12,COPS4,IFIH1,ZMPSTE24,NUDT5,ZCRB1,TRIM26,PLPP6,PPP1R2,EGR2,RPS27L,ARB2A,SNRPA,YBEY,POLR2I,WBP11,FCF1,MRPS33,SMG5,DCTPP1,USP8,VCPKMT,RC3H2,SELENOO,ACHE,TRIM11,PFDN6,MSRB1,KCTD17,LYPLAL1,FKBP1B,ERLIN1,CBFB,HSP90AB1,PTPRZ1,CD28,OST4,PELI3,MARCHF5,REP15,CDK5R1,WDR45,DAD1,POLR3GL,SOCS4,EIF2S2,USP15,HSP90AA1,THOC2,MRPL16,PMPCA,HNRNPA1,WWP2,DNAJC19,SPON1,KLHL7,SLU7,HSPB2,SCNM1,PRDX3,TDRD7,APOBEC3G,SELENOF,ANAPC4,CREB1,CWF19L1,BAZ1B,PRCP,P4HA2,CDK7,CISD1,MRPL36,MACROH2A1,PFDN2,NABP1,EDEM1,USP14,SNRPA1,SNRPE,AHSA1,PAGR1,PRKCB,WDR3,CTBP1,EIF3J,PXYLP1,TTC4,QNG1,NPM3,TRIM37,USP13,PTPN22,GAL3ST1,NFKBIB,UBE2F,AP5S1,FARSA,RTCB,VPS4B,RP9,PIWIL2,DTWD1,FCN2,METAP1,PAK6,QPCTL,SRPK2,RBM7,KLHL12,SNRPD3,POLB,RNF39,TCEANC2,SHOC1,SNAPC1,RING1,PCNA,RNF187,RNF20,BTG2,GLE1,STK24,DCP2,CCNA2,CSNK1A1,RPL23,LIPA,GAPDH,MYRF,CNOT7,CLN8,POLR2L,LSM6,RAD21,UBE2H,ITK,AASDHPPT,MRPL47,PCYOX1L,EDEM3,FBXO22,RPS5,CEP41,PIWIL4,FGFR1,ATXN1L,VASH1,TTLL10,PTPRQ,HELT,NDUFAB1,TFPT,NONO,CDK6,UGDH,FBXL7,CTRB2,SEC11A,TSEN54,MRPS18A,TRIM27,FKBP10,ENC1,POLR1B,CCL11,HUWE1,PTPN11,ORC6,SPPL3,GNPTG,PFDN1,TAF7,VPS4A,ZNF451,VPS72,EEF1AKMT3,ZMAT5,APEX2,IL21,STK38L,AIPL1,RPS16,LDB1,MTRES1,DIS3L,KTI12,DDR1,SCN2B,PSMD14,RPS28,UFM1,TRIR,FBXO3,BOLA2B,PPAN,SPHK2,ATG3,RPF2,QRSL1,ANKH,TRIM23,OGG1,H2AX,PLEKHJ1,SPCS1,FBXW11,RAG1,INO80C,PIR,MINDY3,STX1A,RPS29,PSMD4,KLK9,MME,BRIX1,BATF,MAPK10,PRPF4,DPAGT1,RNF182,CAB39,S100A10,ROCK2,GALNT2,APPBP2,ADIPOQ,ETF1,SENP8,TRIM6,TMEM106B,EEF2,CINP,RPS3,TRAF2,FBXO31,TIA1,ESS2,RWDD1,METTL2A,INHA,ECRG4,MRPL22,RBFOX3,ENPEP,DPH5,EIF4E3,APTX,SNAPC3,LYAR,ELK1,CHMP2A,SIN3A,GANAB,RPLP0,RMI2,RMND1,H3C1,SNAPIN,POLR3F,MPHOSPH10,RPL26L1,HSPD1,MRPS7,RNF122,OVGP1,OSGEPL1,THUMPD1,WSB1,ADGB,MRPL11,GNMT,LUC7L3,DUOXA2,RNASE6,UBE2E2,POLR3B,UBE3A,SNRPB2,RNF14,DPP10,ASMT,STOML2,UBB,CAMLG,USP2,COPS7A,PSMB3,HTRA1,MARCHF4,RIC3,TRIM24,ATG4C,WDSUB1,GYS1,CTDSP1,CDK12,SKP1,PLAA,TSPAN15,CHPF,CDKL2,DERL1,BAD,B4GALT7,PSMD7,KPNA6,EIF3G,GSK3A,PPP1R8,AKAP17A,MRPS35,GON7,DPH3,UBE2V2,GMNN,CDC7,RNASEH2C,DDI1,MRPS34,SDHAF2,ISG20,UBXN6,SELENOS,GRB10,PRMT5,CSTF3,WDR77,RPN1,NPC1L1,HSD17B10,GEMIN8,EP300,RNF103,RFC3,RNF208,TMEM106A,CRTAP,RPF1,CTSK,BACH1,DNAJC5,PQBP1,STYK1,IRF1,SLC30A5,PIGK,UTP15,C1GALT1C1,TMEM208,MAN1A2,KRR1,HS3ST3A1,NBN,FBXO44,METTL14,PGK1,IFI16,RPS24,NTRK2,TFIP11,CCT5,UBL5,B4GALT4,MECP2,EDC3,MRPL50,BNIP3L,CELF6,EXOSC3,LYPLA1,BMPR2,ADGRG1,CDK20,MSRB3,SRC,PPIL3,SUMO2,PPID,PSMB4,ANGPT1,XPNPEP1,PTGES3,GXYLT2,EXT1,SRGN,MTMR2,NRDE2,NOVA1,POLR2F,TRIM21,MGAT4B,ATF4,SF3B6,HNRNPK,PSEN2,ISCA2,METTL6,CHPF2,FAU,RNF121,RBM27,TENT2,ZRANB2,MACROD1,BIRC5,DTL,RPL8,MEIOB,USP30,DHX38,PRKRA,MEF2A,MRPL53,CCNF,TRAF6,NLGN2,NAE1,TTC1,THBD,NUDT12,TRIB1,SYCE3,RNF40,TMEM59,TXNL4A,HNRNPF,RPAP2,MRPL18,CLPX,PRSS37,PHKA1,IRF2BPL,FBXW4,FOS,CHI3L1,PRSS12,SUPT3H,LIPT2,P3H1,MGAT4A,RNASET2,B3GNT2,NFKB1,KCNJ8,WDR83,UBL4A,ZDHHC4,TYW3,FNTB,SNRNP27,DNAJC4,ELP3,SMAD3,TRMT1L,DUSP22,GPAA1,ATG16L1,CMTR1,IRF2BP1,TRIM62,NXT2,SELENOK,HNRNPD,TAF9,SNRPN,KMT5B,EIF4A3,TEX19,GTF2H4,IL4,THAP1,MDC1,PSMB10,NTMT1,CDC37L1,PAAF1,RPL37A,DGCR8,FXN,PDP2,FAM98A,F9,RPL17,CSNK1G3,TRMO,GPBP1L1,CYP3A43,YAE1,RUVBL2,USP5,SWAP70,RNF7,CMA1,REN,SHPRH,EIF5A2,PCSK2,NXT1,RNF34,SETD7,STK3,FBXO8,MAP3K12,UST,TRIM68,TLR3,DDX42,RPS14,DYRK2,CDC16,SREK1IP1,FZR1,CRYAB,AGO1,SECISBP2L,SOCS2,MTMR6,PPP2R5E,PPIG,BAG3,ERO1A,SOX9,PCMTD1,SART3,NDFIP1,CBL,PTPN5,CPSF4,HNRNPA0,CPEB1,CSNK2A1,QTRT2,MTRF1,LSM8,DCAF5,DNAJC25,RBM23,CWC15,IMP4,OTULINL,CDC5L,DHX15,ANAPC11,CTSB,PPTC7,PELO,ING5,PRPF19,XXYLT1,FKBP1A,CTTNBP2NL,EIF4EBP2,NUCKS1,SNRK,VIPAS39,HSPA14,DRG1,RPP25L,GLRX2,RFC2,DBR1,CHRAC1,FKBP2,MCM8,PRDM4,CFAP20,PRSS1,DDX4,ADRB2,ZNHIT6,SRSF7,THOC3,ABHD13,SF3A1,STAT6,RNF8,FAM8A1,DUSP3,LRWD1,ZFAND2A,KLHL15,ST6GALNAC3,DPEP1,TMUB2,CHST9,PLD3,GFM1,LTO1,GZMK,SMNDC1,LORICRIN,RPRD1B,OTUD7B,LSM2,SUGP1,AANAT,ASB7,B4GALT3,DDX46,NAA35,CAMKV,FYTTD1,TRA2A,TRIM52,LYG2,PPP2R3A,TRMT61A,UFL1,RBM15B,CHMP4C,RBM3,TRIM15,CDC123,LGALS3,DET1,METAP2,KPNA2,WDR6,HEXB,DROSHA,PIWIL1,FAF1,ZNF326,INTS10,PTPN1,BAG2,PPIB,HSPA8,ZNHIT3,RPL9,ZNF473,ALKBH3,RARS1,USP39,MRPS11,CLCA1,ST3GAL4,CRBN,FBXO30,RBMX2,PSMB5,SUMO3,PYGM,TP53,SPCS3,MAP1S,HENMT1,MPG,AGA,MDM2,TRMT13,DDX5,NCBP2,RPL35,NLRP3,KCTD9,BOLA3,PPM1D,RP2,H2AB1,GGCX,CSNK2B,CHST7,RNF133,CASC3,NHEJ1,ABCF1,FUT8,LCN1,SUPT5H,LSM3,MED4,TOP1,TNFAIP1,CD2BP2,ZNF365,CASP4,RPL6,ILK,RNF152,KLHL9,PLAC8,RSL24D1,RPL28,CDK5,STUB1,DNAJC10,CCT8,GTF2A2,DUSP10,KDM2A,HECW1,RNF5,PCLAF,GINS4,DUSP18,MUL1,PPT1,EXD2,ERLEC1,PHB1,RPA2,TEX12,ZBTB16,ATG7,HDAC3,UBA3,JKAMP,UBE2S,PSMB2,TNIK,B3GALNT1,MMP20,RAMAC,PREP,HM13,RIMKLB,AQP11,DNAJB6,WNT10B,GFPT1,URM1,RIGI,UQCRC2,PAX6,SLC35C1,TP53INP2,NUS1,PRKAG1,TUFM,CASP12,RPL7A,CHMP2B,OTUD6B,BABAM1,AKT3,FOXP3,RCL1,ACTL6A,PPP1R12A,PPP2CB,TENT4A,KLHL25,DUS4L,RPL12,CLIP3,RNF181,MCM6,UBE2K,MMP14,MAGEC2,IMMP2L,POLD4,POP5,THOC6,CETN2,DDX39B,PADI2,CHMP1A,EIF4E,UTP6,NDST1,SPSB1,RPL27,RPL13A,XBP1,TERC,DOLK,MND1,PFDN4,MRPL52,SOD1,AR,SNAPC5,PAIP2,HIRA,TRIM63,CYTL1,PAK2,IL2,USP46,B4GALT1,PCSK9,PPP3R2,RPL4,TAF11,RGMA,SMU1,DIO2,PARL,SRFBP1,B3GALT2,PSMA3,PRKCE,GLCE,BMP1,SIAH2,CEBPE,RPL26,CCT7,PDRG1,GPC1,FKRP,DUSP26,RPS4X,FUBP3,FBXO9,PSMA4,SIRT7,PSMD6,CLK4,PPP1R11,FEM1C,B4GAT1,VDR,BAK1,CTNNBL1,TERB2,PRKACB,RNF148,YWHAZ,CDCA3,KLF1,ST3GAL5,VKORC1L1,CDC40,CAMK1,STT3A,HS2ST1,DEK,AREL1,CAPN2,NUDT16,EIF3E,RRM1,PPM1B,UNC45A,NSMCE3,RPS11,SAMHD1,PPM1K,GTF3C4,METTL21A,CTSA,VRK1,ALKBH2,CLK1,ADPRH,ASB11,RB1CC1,CHTOP,RBM41,RNF41,PARP11,CD40LG,UTP25,BACE1,RPL35A,MAP3K21,CHST13,DPH6,ZC4H2,APEX1,FBXL3,TAF10,F7,CDSN,ZFAND2B,RPS10,ROCK1,GFM2,RHBDL3,THOC1,SUPT4H1,MYLIP,MRPS25,TBCEL,USE1,PRPF31,C1D,DMPK,APOBEC3A,TBK1,XRCC5,CDK4,DPP4,RPL7L1,VPS54,TRMT10B,PIAS1,RBM42,EIF5B,KIN,DNAJC1,RMND5B,NPPC,RPL10A,DUSP6,GCFC2,CCL2,GLRX5,PSMC5,HNRNPL,SYK,NLRP1,MAK16,PPIC,APOBEC3C,TRIM5,ZC3H11A,SELENOT,FBXW7,TESC,S100A8,EAF2,ZDHHC17,RBM17,DCUN1D5,APEH,UBAP1,VSIR,MED23,KBTBD6,PSMC4,CNOT6L,TRIM32,UBE2L3,TRMT112,MED9,SMAD2,BRCA1,ALKBH5,BUD31,RBM22,MPHOSPH6,IRF9,RNF113A,PSEN1,TNKS2,MTM1,MRPS21,APOBEC3F,MRPS23,UBE2I,SNRPG,SNRNP70,IDE,RBFOX2,NDST3,TAB1,TNKS,MTG1,CELA3B,MEPCE,COQ8B,PPP1CB,RBBP8,SOCS3,PRDX4,ST3GAL1,RPP14,POLR3H,CDKN2D,PIM2,NAA60,CDK1,SNIP1,SSBP1,POLR2D,ATP6AP2,RPS6KA4,APOBEC3D,NAA50,CTDSP2,PWP2,UBE2A,MED21,NFIL3,MRPS26,PREPL,FAAP100,MRPS28,DAPK1,FAF2,CDC20,ZSWIM7,HSPB1,SLC35A1,TDP1,MARS1,FBXO11,TYW5,RPL23A,ZER1,ACTMAP,MTF1,MRPL9,FEN1,AIP,TRIM22,PYM1,PTTG1,ADAMTS20,HSPE1,CSTA,COIL,XPO5,CCT2,PGPEP1,SMAD1,EEF2KMT,SUMO1,COPS5,METTL25B,HNRNPC,RNF126,SETD3,FOSL2,ORC5,EIF2D,DYRK1A,PRSS23,RPL22,CREBBP,PROX1,ZDHHC24,KLK3,MARCHF3,MPDU1,PPP1R3C,GTF2H5,ADAMTS10,MRPL40,KRAS,DCAF11,STBD1,DPY30,FBXL4,ADAMTS1,DRG2,RPP21,IL2RG,TWNK,PRKCQ,SESN2,GOLGA7B,UFD1,HECTD1,UBR7,COP1,SPCS2,JOSD1,B4GALT6,DESI1,ST8SIA4,PPARG,POLE4,EGR1,CHCHD4,IKBKB,MKKS,FANCG,NR4A2,MNAT1,CUL2,EPO,PTGDS,UPF3B,EZH2,YTHDF2,RPS20,EIF4H,NCSTN,RRP7A,CHMP1B,SRSF1,CMTR2,TBCE,COMT,PSENEN,POLE3,DNAJC2,EYA3,DDIT3,SMG9,DCLRE1C,SVBP,LCMT1,ERCC3,FKBP8,NOP9,CTSC,CHST10,ABCC5,PGAP4,UBE2D3,EIF4E2,ACVR1,RAD23B,PRKCA,LMAN1,MCMBP,GANC,RNF144B,WDR83OS,CAPN1,HSD17B1,POMT2,PPIH,EDEM2,F2,SH3GLB1,RFC4,HSP90B1,USP16,APOBEC3B,RABGGTB,INPPL1,PGGT1B,TSEN34,FRA10AC1,UBE2E3,DCUN1D1,EEF1B2,TFB1M,CGAS,NUDT3,STRADB,TRA2B,VPS28,KLK6,RAB6A,H2BC1,HMGB1,DFFA,KCTD11,FEM1A,MBL2,ABHD17A,ZDHHC8,CARS1,CD226,BCCIP,HNRNPH3,GTPBP1,GID4,SRSF2,RAF1,SRSF8,STN1,DDRGK1,MAP3K11,POLDIP3,RBBP7,NAA15,MMP21,ZC3H15,PRKX,PPP1R1B,RFC5,TRAF1,MSX1,SYNCRIP,NGDN,MAEA,JAK1,UBE2B,CREBL2,RHOBTB3,SMURF1,ECD,EEF1G,RPS2,PHKG1,CPNE1,KLHL24,WDR82,ELP6,ANAPC2,NEURL2,MLH3,HSPA13,RPS23,IFI27,KHDC4,MED29,LIG3,SRSF10,HYPK,DXO,RPLP1,BAP1,PMAIP1,CD36,AURKAIP1,LDLR,DMAP1,TRIM34,TOP3B,HAS3,ST13,PPARA,PELI1,RPL39,TRAF7,PAK5,PPP4C,GAL3ST4,EEF1A1,NEUROD2,BRAP,RPS17,FGR,RNASEL,THRAP3,NIM1K,VIRMA,ERP29,PI3,KBTBD13,STAMBP,GTF2F1,CSK,EIF2AK2,POLL,MRPS18B,SEC61B,HPF1,RIOK2,UBE2N,RRN3,DESI2,NUP153,UBE2M,PSMC3,STK26,TSR2,CAND1,USP3,GALNT17,INTS6L,DDX39A,FBXL19,MORF4L1,MED31,JAK2,PTEN,DTD2,UGCG,ACACA,TUBA1A,ABCE1,SMCHD1,POLR1D,ASF1A,DCAF16,PHETA2,NOP53,UBE2V1,UBE2G2,ASB3,INO80E,SMAD4,PDIA2,MAPK4,LSM4,RNF128,DNASE1L1,RPS27A,NAA16,PSMD12,EIF3D,PRKD3,ARMC8,POP7,KARS1,RPSA,DR1,SNX5,TTL,MAGOH,KLK5,COPS7B,TSNAX,CYFIP2,NTAQ1,CTNNB1,SLC1A1,HYAL2,SHLD1,TRIM3,DTWD2,PHKB,GTF2IRD1,ALYREF,MGAT1,EIF3K,EIF1AD,RPP25,EIF2B5,SNAPC2,BMPR1A,GOLGA7,SMARCB1,NOB1,IVNS1ABP,PRMT6,DNAJB4,NFE2L2,FBXO7,GCNT3,PDIA6,SMUG1,SRSF4,SPSB3,UBASH3B,DRAP1,TMEM199,DAG1,SMARCA5,EIF1B,SERPINH1,PIWIL3,CSTF2T,MMP28,NME1,SNRPB,MCM3,POLR2G,RAB40AL,LEP,SQSTM1,CBLL1,TCOF1,MRPL51,GALNT1,MED17,RNF146,CPSF1,SENP5,METTL22,TRIM45,STK16,TESK2,ELOF1,CSGALNACT2,NAA11,GADD45A,UBLCP1,FKTN,DNLZ,NDP,CD2AP,NEK2,FAM20B,DNAJC7,TSR3,ZDHHC16,TPST1,MRPL24,UTP23,GRM2,SNRPD2,PML,BMPR1B,TFCP2,UGP2,RPL32,DISC1,PABPC1,UBXN2B,MRPL33,MRPL20,RPL24,EIF2S1,FUT9,HS3ST1,SPATA2,GTF2E2,TERT,RPL19,CISH,ANAPC13,OTULIN,RPL3,MED30,CLU,GRPEL1,STK38,PSMA1,PKNOX1,RPS7,RNASEH1,EIF1AX,ATG4A,NT5C2,TEX264,ELOC,POLD2,PNRC1,MYD88,TRIM54,TAF5L,KLHL3,HTRA2,SPOP,HSPA5,SOCS5,NUDT1,LSM10,IGFBP3,MRPL57,RPL10L,FURIN,SNRNP48,RPL18,EEF1E1,THG1L,FASTKD5,ALG5,ANAPC15,STAMBPL1,FBXO25,RPS9,MRPS16,HERC3,PMM2,SLC6A7,SRSF12,OSGEP,ETFBKMT,GTF2F2,IL6ST,BARX2,TSSC4,EPHA4,GBE1,PELP1,ZDHHC15,TUSC3,ABHD10,PPIA,PGAP3,RCHY1,FBXO32,CSNK1E,IFT172,RTRAF,ARMC7,IGF1R,PDF,OLR1,MRPS17,ALG11,IL1R2,NSA2,HCST,RPL7,TMT1A,SUB1,EXOSC4,BANF1,DNAJB9,CNOT6,UBXN10,SF3B5,DLG1,CHST11,TOPORS,BECN1,TNNI3K,GXYLT1,ZCCHC7,DICER1,PSMB1,POLA2,KDM1A,OS9,NHP2,ZBED1,TLR7,TSN,BUD23,RIMKLA,CTU1,PPP1CC,MAP2K1,CCS,HGS,PRMT2,RPA3,SEPHS1,DHX9,SDF2L1,FEM1B,FAM20C,RMI1,MSL2,COL3A1,RNF167,ZNF345,MARCHF9,GINS3,GALNT4,CCR6,ISG15,GTF2B,RLIM,NEDD8,TPSG1,UCHL3,RPL29,EIF2B3,PGAP2,TRIM8,TRMT5,ZMAT2,LTB,RNF11,PCMTD2,SUV39H1,PPP2R1A,CHMP5,MRPL10,NQO1,SNRNP40,KLHL22,PPWD1,BPNT2,ALG2,RPL15,SGTA,APOBEC3H,F10,GMPPB,MLF1,RBCK1,GAPT,TRIM44,PTPN4,SIAH1,RNF139,ZNF668,HINT1,HMCES,ATAT1,EIF2B2,PRIM2,GTF2I,TCEA2,RPS26,GPHN,PSMB9,GABARAPL1,B2M,LARGE1,GEMIN7,CHORDC1,ITGAV,CNOT8,TRIP4,EMG1,MGMT,SAP18,RAD1,POLR1H,TMEM165,TSSK1B,RPS15,TLR4,IMP3,KLF4,B3GALT1,TOR1B,STK4,VCPIP1,CIAO1,ST6GAL1,MAEL,CDC26,DDX23,PIGC,NEK7,LEPR,PTAR1,MCM4,CSGALNACT1,ANAPC16,FTSJ1,ASCC1,ZC3H7A,TNFAIP6,EPOP,MAP3K3,FBXL14,PPP1R1A,CNDP2,GTF3C3,CEBPG,RBM38,CNTN1,SNRPD1,CHST2,GALNT12,CTSD,OTUD6A,MAPKAPK3,PYGB,MFAP1,CDK9,RBM5,NFYA,TYMS,RSRC1,RB1,IK,RNF141,PRPF18,SH3BGRL,RAB11B,BCL6,PFDN5,TOPBP1,NSFL1C,BCKDK,TOP2B,SSU72,PLG,CSKMT,PSMD3,EPHB6,MED11,MRPL34,HINFP,TMUB1,SF3B1,HMGA1,TNF,GRPEL2,PSMA2,PDIA3,PDE12,RUVBL1,CDK8,PSMB11,SMG8,PPP2R5A,RPL10,METTL18,ADM2,DNAJB2,RBM34,CDC73,SRD5A3,DTD1,B3GALT4,DNAJC3,ST3GAL2,DHX16,MGME1,RPL27A,EDNRA,NMI,MAD2L2,PAPOLA,PSMB6,REXO2,MED27,GTF2A1,NCAPG2,DUSP21,ASRGL1,VPS18,EXOSC1,PIGW,TAPBP,UHMK1,ERRFI1,DHPS,FUT1,AKT2,PSMA6,HS3ST5,HECTD3,RPLP2,COPS2,SLX1A,DAPK3,SMN1,OXSR1,SF3B4,POLR2C,ZDHHC14,ERLIN2,DDX1,DNTT,NKX3-2,DCAF4,ACVR1C,MMP9,PAIP1,LSM5,ADAT1,PSMB7,NOP58,USP38,GP9,HEXA,TRAF3IP2,IL6,TOM1L1,LAMP2,KIT,TSPAN5,COQ8A,TOLLIP,CPE,EIF4A2,HNRNPAB,UBE2D1,MSH6,TGFBR2,NR1H2,SLC25A26,FTSJ3,MATCAP1,E4F1,PPP5C,TSG101,RPRD1A,CDK5RAP3,SYVN1,SPRR1B,FN3KRP,EGLN2,DOHH,PAXX,SCPEP1,AKT1,DYRK1B,IL1B,KBTBD2,ELAVL4,HERC4,PPP3CA,CLP1,DNAJC24,ADAM21,SLAMF9,EIF4B,RTF2,MTERF2,METTL15,EXOSC8,UBA52,CHCHD1,GRSF1,PSMA5,CALR,NSG1,SKIC8,APH1A,IGF1,DKC1,WTAP,CNOT2,ENY2,UBE2W,MRPL23,RBBP4,TNFAIP3,NUDCD3,GID8,PSMD1,PGA4,CPSF2,ZNRF1,CCDC47,TRIM10,RAN,PIK3R1,SETD4,CUL3,CDK17,SSRP1,MRPL49,TRUB1,TCP1,ASB8,NIBAN2,PIGY,PPM1G,MRPL41,GTPBP2,RCE1,BCL9,HSPB6,RPS12,GTF2E1,IL15,RNF115,CCAR1,PRRT1,RPL31,TOR2A,G2E3,WRAP53,TRIM35,CHST1,GTF2H2,HNRNPA2B1,TRMT11,ANKIB1,GIN1,CDC23,RBMS2,NUP107,WDR12,SPOPL,CAMP,ADRM1,WDR55,MAGOHB,CACUL1,LYPLA2,OARD1,RPS13,TLR2,ST8SIA5,DPEP3,FKBP4,CYP1B1,MRPL12,MRPS9,PPM1M,GTDC1,CCNH,DUSP9,MRPL13,TRMT6,RNF26,PPIF,YIPF5,RNF10,AKAP8L,PICK1,CSNK1A1L,POLR2B,EHD3,MAPKAPK5,WBP2,MGAT5B,H2AC25,MRTO4,EXTL2,DCUN1D3,CHRM3,PIH1D1,PIGA,SCG5,DERL2,ACVR1B,MED10,NOC4L,ARFGEF1,PSMC1,PPME1,BFAR,STK11,TMCC2,ALKBH4,MED22,LAP3,CCAR2,FOXA3,POLDIP2,NME2,DPM2,INTS12,NOL7,HDAC6,MRPL17,SGF29,XPO1,TCEA1,KCTD10,WEE2,PRSS8,PARP2,PRKAB1,NPC2,ASB1,BIRC2,DUSP1,YES1,EGLN3,MRM2,LACRT,MRPS18C,GLUL,RLIG1 |
| 4.319e-10 | -21.56 | intracellular vesicle | cellular component | GO:0097708 | 2527 | 867 | 19108 | 5553 |
SERPINA1,SYPL1,TUBA1A,RAP1A,SELL,PRSS37,TRAF3IP2,CYRIB,SYNGR2,ICA1,NPPC,RAB18,NCDN,CLRN1,VTI1B,BOK,FCHO2,BLOC1S3,GABRA2,CHP1,EPHA4,ITM2B,VDAC2,CYB5R3,LRAT,ARMC8,ROGDI,SNX5,PTPN1,CARTPT,HCRT,PRDX4,RAB40AL,SLC48A1,KDELR1,EHD3,RAB33A,DISC1,RAB3B,IL2RB,TLR2,AP1S2,LDLR,WDR44,PSMD14,SH3GLB1,IL2RG,SEC22B,PROS1,CD274,CD164,CD46,GRIA2,B4GALT1,CYSTM1,HGS,RAB33B,MT3,BET1L,GRIA1,ERP29,FGD2,SLC30A7,TUBG1,SGIP1,LACRT,RETN,TP53INP2,SFTPA1,ANXA7,SLC35G2,CST3,EEF2,AKT2,CDC42EP4,GOSR2,VEGFA,COTL1,CLEC18A,HSP90B1,OPRM1,NSG1,DDIT3,UBXN6,ZNRF1,FTL,AGTRAP,NRSN2,TEX264,GPC1,RHOBTB1,PHB1,CAMK2G,GCHFR,GABARAPL2,LAMTOR3,MMP14,PSEN1,RAB14,GH1,PSMA5,CD9,ABHD6,STX7,ATG16L1,CPNE1,PLA2G4B,PCSK9,HEXA,KLHL12,IL12B,ATP8A1,KCNJ11,RNF133,RAB3A,SNX11,STXBP1,AGAP2,ATG7,CD2AP,GJA1,MMP9,SCAMP2,RAB13,NRSN1,RACGAP1,SEPTIN6,ZYX,SLPI,PLEKHF2,ARF6,GABRA1,RAB31,TOR4A,NRBF2,DNM2,KIT,CHIC2,TRAPPC2L,CLCN6,RP2,BRI3,SLC35F1,HPS6,SYNGR1,RGS19,PLCB2,VPS18,MYD88,GDI2,RAB1B,KLK9,TMEM198,GZMK,TMEM30A,GOSR1,PDLIM4,PTP4A3,HSPA5,DNAJC5,FCGR2A,ADRB2,ERG28,RARRES2,DYNLL1,SLC6A4,TASL,CPTP,VPS54,UBA52,AP1G2,ABCC5,CAND1,TREML1,HSP90AB1,FURIN,ACTR1B,RAB9B,ATP6V1G2,EHD4,SDCBP,XRCC5,RHOU,GRAP2,SCFD1,PRL,ACAP2,CTTN,LHFPL2,USE1,ENPP4,VAMP1,CLU,ACTN4,TMEM108,RAP2C,YKT6,LYZL6,TM9SF4,GHRL,WASL,AGA,FGR,JUP,CD59,SYP,AP5M1,DSN1,NIPA2,MLC1,ORMDL3,MDM2,FOLR1,SYNDIG1,PITHD1,HP,PSENEN,ANKRD50,SIGMAR1,CD14,NECAP2,PGA4,CTTNBP2,AP3S2,ADD2,TLR8,VAC14,MBL2,DLG4,MYO1B,VIPAS39,SNAP25,WDR11,RAB1A,SELENOP,CHMP1A,FIG4,IDH1,SYT2,HSP90AA1,CLBA1,TRAPPC1,TBC1D17,PGM1,MYO6,RHCG,CHID1,WDR83,CD4,STX16,CX3CR1,SLC2A1,STMN2,HMOX2,COPE,DPEP3,CYB561,EHBP1,ITGAV,HFE,TMEM59,GABBR1,GPR15,PSMC5,TLR4,CXCR1,MREG,TNIK,SIAH2,LDLRAD4,CD1C,ATP6V1E2,NEU1,RNF128,CRHBP,B2M,PDAP1,PPFIA3,SLC38A9,PLG,TRAPPC14,CHMP1B,ATP6V1A,SPTAN1,OLR1,RNASE6,IL15,SCG2,TEX261,ARHGAP21,MTMR2,ADRB1,CCT8,NECAP1,UBB,IFNAR1,STX6,TRAPPC13,PDE6D,SPACDR,IL15RA,EMP2,DPP4,CTSA,TM9SF1,TMEM106B,TAB2,RPS27A,SYBU,YWHAZ,RAP2B,ABHD17A,SQSTM1,GABRB3,DEGS1,ATP6V0B,CFAP119,TBC1D24,PYGB,RAB39B,CHGA,SNAP29,AFTPH,LILRA3,TOLLIP,MAP2K1,TIRAP,PLEKHF1,RAB8B,IL1B,TMED3,DKK1,RNF167,MAGED2,OVGP1,DNASE1L1,BCL2L1,VTA1,MARCHF3,CTSD,ALB,CDC42EP2,SLC11A2,CTNNA1,TLR9,NPTX1,MMD,STX12,CNIH1,PSMD12,CCR5,APH1A,RALA,SCAMP5,LAPTM4A,AVL9,GNPNAT1,LGI3,PGRMC1,RAB5C,SYN3,CSTB,TMEM123,SERPINA5,NTRK2,MCOLN1,CHMP2A,DYNC1I1,AVPR1B,SERPINB10,STX1A,RAB35,YPEL5,RAB9A,CDIP1,CSH1,TMEM165,NTF4,SEC13,TLR3,TRAK2,ATP1A1,KCNH1,ENPEP,TAX1BP1,TBC1D10C,RAB27A,HILPDA,TIMP3,IL12A,SLC1A1,TICAM1,SLC39A13,SEC23A,PADI2,ATP6V1G1,PSMD7,GANAB,LAMTOR1,SRC,JAK2,KLK3,CHMP2B,CD1A,STX17,SSPN,STX8,PLD3,GPR89A,AP1AR,TOM1L1,SFTPD,SYK,SCYL2,PHETA2,VWF,TNFRSF1B,HCLS1,RAN,ABCB9,SFTPC,SUV39H1,SLC4A8,CD47,AP2S1,CLIP3,STX11,TRIM3,FASLG,FCAR,ATP6V1D,SPRED2,PDE4B,AP2A1,RNASEK,TESK1,CXCR4,SRGN,CD1E,PDIA6,CTSB,GGH,OCRL,CMA1,WNT7A,TBC1D5,RABAC1,CAMKV,LYZ,PTP4A2,CD1D,OPRL1,PSMB7,CCDC22,CAPN1,OCIAD2,LYZL4,PLAC8,STARD4,CAPG,AQP11,VPS28,PRDX1,OCEL1,ILF2,LGALS8,COPS4,CAV2,GOLGA5,DERL1,USP8,FGL2,SLC12A2,CD36,PRSS12,HERC3,TRAF7,HBA1,KLK5,AQP2,ITGB5,TFRC,STAMBP,VAMP2,ANXA4,SNX10,CHMP4C,SVOP,DVL2,ACTR2,PYCARD,TICAM2,TMEM190,HSD17B6,NDUFC2,TGFB3,RPN1,PDIA3,HDAC6,FZD4,TRAF6,TRIM21,STAMBPL1,PICK1,SERPINA3,PACSIN3,LPAR2,DBH,GLIPR1,DNAJC3,SRP14,PAFAH1B2,TP53INP1,SNX20,RAB5A,SLC66A2,NCSTN,SH3BP4,ENTPD4,HYAL2,MTM1,TRIM27,TMED4,VAMP5,CXCL1,KLK6,NPC1L1,EHD1,SLC1A3,ARCN1,RNF11,PSMC3,AMELX,COMMD9,LRP6,EXOC3,VPS26B,RUSC2,SLC15A2,CCT2,PSMB1,ATP6V1C1,CDKN1B,SLC31A1,SNX24,SEMA4C,LAMP2,VPS26A,GTPBP2,MIF,TMEM168,SCG3,AQP4,FAF2,HEXB,BST2,PRDX6,ATP1A2,TAPBP,CALY,LAMP5,RND2,TRAPPC3,TMEM33,SNX14,PICALM,HAS3,TBC1D25,PSEN2,RAB29,STBD1,RAP1B,TMUB1,PML,IRAK4,FCER1G,GAD2,USP14,BACE1,GSTP1,COPS5,TLR7,LAMTOR2,SNAP91,USP6NL,OR51E2,ARPC2,CALML5,NCALD,VAMP7,APEH,JAK1,GNAI2,FABP5,PCYOX1L,VPS16,TNFAIP6,IZUMO1,HEBP2,GCA,ATP1B3,LMBRD1,ABHD2,ADAMTS1,CYB561D2,FAM91A1,PRRT1,PNP,RAB37,ASTN1,STX10,RAB11B,PSMA2,HSPD1,CD58,RAB32,RNF148,STX5,NPY,CACNG3,PSMD1,DERL2,GABRG2,SNX17,RAB6A,RAB3D,CIDEB,PRDX3,STK26,TMT1A,LY96,SRI,SNX2,PARM1,OPRK1,SNX22,REP15,REEP6,CAB39,SERPINB6,CLVS1,TCP1,MOXD1,TRAPPC6B,MRC1,OLA1,LGALS3,BPIFA2,CPE,TMEM179B,IGF1,TRIM36,GABARAP,TUBB,RAB11A,RAB6B,EEF1A1,SYNGR3,NPC2,PLA2G5,GABARAPL1,YWHAB,LMAN1,TGFB2,KDELR2,FZD6,YIPF5,CTSK,TRAPPC4,HTR2A,SV2B,PSMD6,TBC1D16,DENND6B,RAB23,ZDHHC17,SVIP,RAB3C,GABRB2,RNASET2,SCG5,RAB22A,ARRDC3,RAP2A,FTH1,EXOC8,TYROBP,BICD2,AZIN2,CD63,CLCA1,PRCP,ACTL9,TMEM95,PIP4P2,CLIC4,VAMP3,TLR1,CMTM6,S100A11,AP5S1,CHMP5,CTLA4,SST,CLVS2,CALU,SAR1B,TIMP1,LEPROTL1,SLC17A5,TNF,COMMD3,SNX33,PPT1,CNP,HBB,TLR6,CPLX3,RAB2A,VPS33A,SLC18B1,INPP4A,GPNMB,STK16,SOD1,BORCS5,SNX3,LPAR1,TMED5,NME1,CORO1C,HUWE1,PPIB,BLOC1S5,MAP1LC3B,BECN1,TSSK1B,RHOG,TF,NME2,PDYN,TMBIM1,ACKR3,VPS4B,UBE2D3,STOM,TMEM199,VEZT,CDC42,ATP6V0E1,SLC2A3,SERPINI1,CAV1,VAMP8,TMEM127,TRAPPC10,SAYSD1,APOC2,LITAF,SERPINB1,TNFAIP1,YIF1A,BET1,TMED1,TMED9,TUBB4B,SYNGR4,AP2M1,CSNK2B,ESD,LAMP3,PATE4,HSPA8,PPFIA2,IFT172,NFKB1,FCGR1A,VPS39,ARHGAP1,VPS4A,TTR,SPPL3,SLC2A8,ATG9A,SNAP23,OPTN,ATP6AP2,NF2,GDE1,CDC37L1,SNAPIN,IQSEC1,TMEM74,SPG21,FCMR,IRF7,VEGFC,VPS26C,TMEM45B,TSG101,FLOT1,PGAM1,SIGLEC5,FCHSD2,NEO1,CTSC,FGFR1,TOM1,PLEKHJ1,SYNPR,RAC2,SLA2,PLEKHO2,COPZ2,GOLGA7,ZMPSTE24,PAK2,CYB5R1,S100A8,TAB1,NUDT1,PSMD3,ROCK1,DIPK2A,PPIA,TPT1,CRHR1,PCSK2,SURF4,CHI3L1,UBAP1,RAB4A,SNX1,SNX12,TMX3,SNX18,STARD3NL,CNIH4,NDFIP1,AP1M1,C9orf72,TMED7,CD3G,TOM1L2,MME,MAP1LC3A,APPBP2,CD1B,CFTR,TSPAN15,YIPF3,CALR,HBEGF,SLC30A5,TMSB4X,PIP4P1,HAX1,CAMP,DIO3,SLC32A1,NRP1,FAM3C,RHOB,HMGB1,SPRED1,SYT4,SYNRG |
| 4.419e-10 | -21.54 | PSMB4 (proteasome 20S subunit beta 4) | protein interactions | 5692 | 207 | 100 | 19454 | 5460 |
RIGI,PSMB10,SEM1,PSMA5,IGF1R,PSME1,RNF8,RAD23B,PSMC3,SMAD1,PSMB9,EEF1A1,H2AX,TP53,FZR1,PSMB1,USP15,PSMD7,CRBN,PSMG2,BCL6,SQSTM1,SYVN1,RPA3,BAP1,PRKCA,UBE2M,GRM2,RPA2,CFTR,PAAF1,PSMC4,VIRMA,ADRM1,PSMC5,PSMA6,CCNF,OPTN,UBE2H,PSMG3,STK24,USP14,AR,RUNX1,FBXO7,PTPN11,PSMB2,AKT1,PSMD12,GCA,PSMA2,KRAS,PSMA1,UBE3A,HNRNPA2B1,HGS,MOB3C,SPG21,FOXJ3,SOX2,GABARAPL1,ISG15,B3GNT2,PSMB5,PSME2,PSMD10,AGR2,HNRNPA1,PFDN5,PRPF19,PSMD3,CNOT2,SKP1,PSMC1,DDI1,MYOZ3,UFL1,PSMA3,HSPA8,PSMB7,PSMB3,ESR2,CLIC4,PSMB6,TENT5C,MBL2,PSMD6,PSMD4,FOXP3,LMBR1L,RIT1,OAZ1,PSMD14,POMP,BAG3,CPSF2,PSMD1,PSMA4,RAB11A,MYC |
| 4.804e-10 | -21.46 | ATP5PO (ATP synthase peripheral stalk subunit OSCP) | protein interactions | 539 | 314 | 139 | 19454 | 5460 |
PPARG,PPT1,PIH1D1,ANXA7,CAV2,NDUFA5,TOMM22,BET1,PRDX3,YIPF5,UFL1,PHB2,ADRB2,RER1,STAU1,G3BP2,PRKD3,EXD2,HSPA8,ATP5IF1,HADHA,RHOB,COP1,ICAM1,RIT1,AUH,MYC,MTG2,FMC1,PMPCA,ATP5F1B,ACTB,CHCHD3,ESR2,MAD2L2,PNMA1,LMBR1L,ACKR3,TACO1,VDAC2,CCDC90B,CYB5R3,DLST,DKK3,EZH2,PDHA1,PTRH2,TOP3B,G3BP1,KRAS,ZBTB14,ATP5F1D,VDAC1,SAR1B,HSPD1,NDUFA4,DNAJB4,OPA3,HINT2,RHOG,MRPS26,PDIA3,PTPN5,NDC80,DDRGK1,NT5C2,RPS10,ADCK1,OPRL1,COX14,PHB1,GATD3,CYB5A,PAK5,FGFR1,GRM2,STOM,TFIP11,HEXIM1,MTRES1,CYC1,COQ8B,CFTR,FBXW7,TOMM20,HSPA5,RETREG2,GFM1,RTN4,UBE2H,CDKN2AIP,NDUFB10,ATP5F1A,CEP70,TUFM,MGST3,SEC63,VIRMA,UQCRC2,CCNF,METAP2,PTPMT1,SURF4,NDUFS3,GFM2,SLC25A24,RNF181,ATP5PB,UBL4A,MRPL11,MTCH2,AURKAIP1,TOLLIP,FASTKD5,MEPCE,MAP1B,SFXN1,ATP5PF,BCAP29,DHX9,P2RY1,TMEM70,TSPO,GRSF1,DPP4,ATP5MG,COX5A,COPS5,CD81,HDAC6,FZR1,EPHB6,ATP5PD,ZBTB2,PLGRKT,COQ8A,AIFM1,SSBP1,COX4I1 |
| 4.911e-10 | -21.43 | PTPN2 (protein tyrosine phosphatase non-receptor type 2) | protein interactions | 5771 | 202 | 98 | 19454 | 5460 |
TNFSF18,DNAJC1,TMED9,TMPO,PTPN1,RAC2,PSMB1,HSD17B11,SHC1,PSMD7,KPNA1,FAM20C,GRSF1,TNFSF8,PSMA5,RBM34,CTLA4,PSMC3,DDX39A,ADRM1,STAT5A,TMOD3,SEC63,SRC,DUSP10,PSMA6,PSMC5,DNAJC10,CALU,PSMB2,KPNA6,HMGB1,BRIX1,PNO1,DERL1,RAB9A,EXOSC4,STX17,SSR1,CDK1,SPRYD4,LMNA,STAT6,TFB1M,PSMC4,ST7,PAAF1,EIF2S1,PSMB5,PSMB4,CORO1C,PSMD10,FKBP4,RHOG,PSMD3,GJB1,PSMA1,G3BP1,PSMA2,ANP32B,AHCYL1,PSMD12,TMT1A,HSPD1,UBE3A,CDK5,JAK1,RPN1,GHR,NUP153,TRAF2,DNAJC25,SNRNP40,PSMD6,STAT1,PSMD4,B4GAT1,SEC61B,PSMD14,FTSJ3,RCL1,SETD7,PSMA4,SFN,BAG3,PSMD1,PSMC1,PXMP2,COIL,HADHA,PSMA3,NUP50,HSPA8,TXNL1,PSMB7,PSMB3,SEC62,OTULINL |
| 4.917e-10 | -21.43 | CCDC90B (coiled-coil domain containing 90B) | protein interactions | 60492 | 218 | 104 | 19454 | 5460 |
PYCR1,MRPS25,LAMTOR1,DLST,TACO1,ATP5F1B,NDUFAF4,CHCHD3,MTX2,PTAR1,NDUFAF3,MRPL12,ATP5PO,NDUFA5,ANXA7,RNF10,HADHA,PDSS2,SAT1,PHB2,NDUFS2,MRPS7,STOML2,MRPS35,CLPX,NDUFV2,MMUT,AGR2,FXYD6,NDUFB8,LY6G5C,MRPS26,PHB1,DNM2,SDHAF2,NDUFS8,PNPLA8,ETFB,NDUFS6,PDHA1,NUDT19,NDUFA12,CDKN2C,HSPD1,HINT2,ETFA,KGD4,ATP5F1D,FLOT1,MRPS17,PYCR2,NDUFB10,NDUFAF2,TNFAIP3,CSK,RGL2,GORASP2,MRPS16,PAFAH1B3,MRPL53,PTPMT1,ACAT1,MRPS28,EIF2S2,PNP,TIMMDC1,NDUFAB1,SAMM50,MRPS34,PAK5,ARL15,GFM1,MRPL41,KDM1A,NME4,MRPL20,POLDIP2,GRPEL1,ATP5MG,COX5A,GRSF1,LYPLAL1,TRMT5,COX4I1,CAMLG,MRPS9,MRPL50,MRPS23,LMAN1,ATP5PD,DBT,NDUFA2,MRPL47,ATP5PB,SERPINB9,BCS1L,PPIF,HADH,NDUFS3,ATP5PF,MRPS18B,MRPS33,SMN1,MRPS18C |
| 4.935e-10 | -21.43 | OCIAD1 (OCIA domain containing 1) | protein interactions | 54940 | 408 | 172 | 19454 | 5460 |
DOLK,COX5A,MZT2B,LMAN1,FUNDC2,COX4I1,CAMLG,SDHB,RAC2,NEFL,GPD2,EXOC3,SLC25A24,MTCH2,SNAP29,ATP5PB,APOO,RAB3B,FKBP8,SLC6A8,UST,ATP5PF,CLPB,BICD2,CISD1,UBE2H,SLC25A1,RAB2A,C9orf72,UQCRC2,INTS12,SAMM50,RPA2,SLC25A51,LPAR1,BNIP3L,HSPA5,CLU,TOMM20,MAIP1,DERL1,RAB9A,CDC23,PEX3,RAB5C,XPO1,PEX13,LANCL1,RMND1,COX14,RAB35,MAGED2,RAB4A,PTRH2,GLE1,CSTF2T,VDAC1,KRAS,USP30,RINT1,UQCC2,FIS1,APEX1,CCDC90B,VDAC2,ANAPC2,FAM83B,TOMM22,PHB2,NDUFS2,ARMCX2,GNB4,AKAP1,RAB5A,DNAJC4,SLC25A46,MOV10,COG1,ARF6,PLGRKT,SLC25A12,CAV1,ATP5PD,TOMM70,ARL10,EHBP1,PTPN1,AIFM1,HACD3,TRAK2,CDCA3,HSD17B11,NDUFS3,GPAM,TIMM8A,DNAJC30,PDE2A,SFXN1,ATP5MC1,RALB,MMD,MGST3,TECR,CCNF,OPTN,COX6C,PDCL,TTI2,ARHGAP1,SEC22B,TIMMDC1,SMC4,YKT6,POLDIP2,MRPL20,RPA3,SQSTM1,MAVS,FXYD6,RHOG,HAX1,MARCHF5,STOML2,ATXN10,NUP35,NDUFS8,EGLN3,OCIAD2,CYB5A,NME1,CYB5B,FAF2,CYB5R1,FLOT1,NDUFA4,TMT1A,SCYL2,COX8A,AKAP14,LMNB1,BLVRA,HTRA2,BAX,EXOC8,RAB11A,SYCE3,TOMM40,PARL,MAD2L2,TNPO3,GNB1,CHCHD3,CYB5R3,SEC61B,SARM1,SYBU,RMDN3,ARMCX3,ATP5PO,MTX2,RND2,ATAD1,HSCB,NT5C3A,FBXL4,PXMP2,EXD2,ATP5MK,HSDL1,TTC1,NMRAL1,ATP5F1E |
| 4.973e-10 | -21.42 | FOXO1 (forkhead box O1) | protein interactions | 2308 | 331 | 145 | 19454 | 5460 |
SMAD3,EEF1B2,RPL32,RB1,CGAS,TOP1,MDM2,SLAIN2,CAV1,HP,TPM3,SMAD4,ID1,TCOF1,RPL23A,DHX9,AKAP12,KPNA2,TF,HNRNPK,ARF4,RPL17,PRDX4,SNRPG,CAPZA1,FAM13B,NEFL,ARPC3,JCHAIN,SRP72,SERPINA1,STUB1,ENO1,CTTN,GNAO1,CALML5,GLTP,RPS12,TMOD3,TXN,EIF4H,CDC20,VIRMA,TFEB,DYRK1A,SRC,AKT1,CCNB1,ATP5F1A,CFL1,NONO,AR,PPIG,COL1A2,BAP1,DDX46,SIRT7,IRF3,PML,TMEM263,PRDX6,SQSTM1,TTR,RPL4,NHP2,HSPA5,SPTBN1,CD2AP,NTPCR,CDK1,LMNA,JUP,HBB,HNRNPH3,FABP5,CORO1C,IGBP1,HP1BP3,SNX17,SLC19A3,EIF2S1,LYAR,PRDX1,RPL6,PFDN5,PPIB,YWHAH,YWHAG,ATG7,XPO1,HNRNPA1,CTNNB1,HBA1,HNRNPD,RB1CC1,LYZ,PDAP1,YWHAB,ZYX,RPL31,SLC25A5,CCT8,PABPC1,HNRNPA2B1,ARGLU1,ABCF1,BAG2,LASP1,HNRNPF,SATB1,ARFGAP1,RPL29,ACTN4,RPS7,RAB6B,RPS23,RPL18,VDAC2,RAN,TAGLN2,ATP5F1B,CREBBP,SFN,HNRNPAB,PIK3R3,BAG3,YWHAZ,PFDN2,COP1,SETD7,FAXDC2,XRCC5,HSPA8,SF3B1,CRY1,EP300,DDX5,LCN1,TRA2B,AZGP1,H1-5,CDKN1A,PPARG,PAK2,NUFIP2 |
| 5.141e-10 | -21.39 | E2F4 (E2F transcription factor 4) | protein interactions | 1874 | 531 | 214 | 19454 | 5460 |
POLR2D,GTPBP1,PPP2R1A,RPL29,ANP32A,TPD52,MCM6,SSRP1,RFC2,PCGF6,ATP5F1D,ASF1A,BAG2,SRSF7,PDAP1,DHRS4L1,HMGA1,PRPF19,MRPS35,PPIA,NOP58,TYMS,HP1BP3,CYP27B1,MRTO4,OCIAD2,MFAP1,SLC25A3,PPP1CB,CDKN1A,COIL,STX7,TXNL1,CCDC86,EMG1,RPS5,PFDN6,ZCRB1,BRCA1,SMARCE1,TOMM40,NIBAN2,PYCR1,MAD2L1,USP5,CLIC4,SNRPB2,MRPL23,RPF1,RBBP4,SNRPD2,SNRPD1,FAU,CYB5R3,EIF3K,SOD2,PPIF,CD2BP2,MRPL11,PRDX4,RIGI,HUWE1,MRFAP1,SEPTIN7,ZC3H11A,CCNY,NKRF,TMED1,CNN3,MPHOSPH10,TP53INP1,MOV10,CALR,TOMM70,NCBP2,SLC25A12,CWC15,NOP9,CAV1,THOC1,MRPL50,PRR3,MYBL2,RB1,LDLR,SMAD3,CDK1,COX6C,MED30,SIPA1L1,FTH1,CCNA2,AATF,PDHB,EIF5B,RTN4,RPA3,PPM1G,CSTB,PRPF4,AP2A1,SMAD2,RACGAP1,DNAJC8,USP14,GMNN,AR,HSPA14,SEC13,NDN,COPE,GANAB,NEGR1,MSN,CTNNA1,ENO1,METAP2,SMARCB1,MTA2,NDUFA12,PPIL3,PFDN1,CCAR1,KGD4,HMGN4,LSM14A,ABCF1,MAGOH,IKBKB,XPO1,QPCTL,PROS1,CHMP2A,RPS10,TCP1,SNRPD3,MAGED2,SIN3A,NCOA5,CTBP1,SAP18,SF3B1,EP300,RAMAC,DDX39B,PYM1,HIRA,SNRPA,CIRBP,TFDP2,FTSJ3,CUTA,MYC,PSMA4,CBX5,SMU1,DLST,EFHD2,SELENOF,SLC25A24,BIRC5,PIK3CA,APOO,IMP3,MTCH2,TP53,CDK4,MEPCE,PDRG1,NUP107,CLPB,TRAFD1,AKAP8L,MAP4,SMAD4,SNRNP70,PPIL4,CSNK2A1,KARS1,CMSS1,USP2,RPS16,MIF,RAP1B,UBE2N,HEXIM1,E2F6,H2BC11,POLR1D,TRMT13,HDAC3,KDM1A,MRPL41,LSM12,EXOSC4,CWF19L1,PRDX6,PML,ATP1A1,AP3S2,CDKN2AIP,ATP1B3,LSM6,RPS17,ARL6IP6,GORASP2,MGST2,MORF4L1,GSTK1,CSTF3,SRC,GPX1,CSNK2B,UBN1 |
| 5.221e-10 | -21.37 | CD274 (CD274 molecule) | protein interactions | 29126 | 351 | 152 | 19454 | 5460 |
SCYL2,HNRNPA2B1,RINT1,LSM14A,JAK1,RUVBL2,PSMA1,PSMD12,MCM6,HNRNPDL,FAF2,TNPO2,TUBB4B,PLS3,RPN1,GDI2,FABP5,DNM2,RAB35,PHB1,PSMB5,CORO1C,EIF2S1,CCT7,HMGA1,DDX50,PDIA3,PPIB,XPO1,SIAH2,EIF3D,EXOC1,CDK5RAP3,CSTA,PDCD1,FKBP4,YWHAB,TMEM160,HADHA,PSMA3,EMC1,RER1,CMTM6,RADX,PHB2,AZGP1,IDH3B,PRDX3,ETF1,KCTD12,CTBP1,FDFT1,LORICRIN,GNG12,CYB5R3,PRDX2,TUBB,PSMD6,TAB1,PSMB6,USP5,CHP1,GNB1,TNPO3,APEX1,PYCR1,CUL3,RAB11A,PSMA4,PSMD1,MCM4,GGH,LMNB1,MDH1,FAF1,SFXN1,ABCE1,CD80,NUP107,HUWE1,KPNA2,FARSA,CSE1L,HSPE1,VRK1,RRM1,IPO8,LBR,ACTR1A,GGCT,VAC14,DHRS7B,RAD23B,PTPN1,SSBP1,STT3A,AIFM1,CD274,SRPRA,SYNCRIP,EEF1B2,ALYREF,SEC23A,CAND1,COG1,TOP1,LMAN1,KARS1,CALR,PGAM1,COPS5,CSNK2A1,TPM3,DOLK,PPM1G,MTDH,SPCS2,WDR3,B2M,NME4,HMGB1,SMC4,USP8,TMUB1,PSMC4,SYNGR2,CAPN1,EDF1,HSP90B1,SSR1,ZNF326,ACACA,PSPC1,TUBA1B,GANAB,EIF2S2,SGTA,MSN,ACAT1,LDHA,RPL13A,TECR,DEK,SLC25A1,PTPN11,CFL1,EXOC5,NONO,SPOP,OAT,ATP1A1,XPOT |
| 5.335e-10 | -21.35 | SYVN1 (synoviolin 1) | protein interactions | 84447 | 306 | 136 | 19454 | 5460 |
KRT8,STX5,CYB5A,MPDU1,PSMB4,ERLIN1,SLMAP,OS9,HSP90AB1,EIF2S1,XPO1,OLR1,DDRGK1,PDIA3,ATG9A,PMP22,CDK5RAP3,JAK1,RINT1,EMC8,KRAS,PSMA1,PSMA2,YIPF3,FAF2,ERLIN2,TOP3B,RPN1,STIM1,GPR37,PSMB6,ALG5,GNB1,ATP6AP2,B4GALT3,SPCS1,PSMD1,RPS29,VEZT,CNIH4,SCFD1,SLC7A11,HSP90AA1,DCAF4,WDR20,HSPA8,PSMA3,ITGAV,UBE2D3,RNF5,NDUFS2,UFL1,RER1,GLRA2,TOR1AIP2,PSMB3,FAM8A1,FDFT1,CTBP1,PSMB7,VAPB,UBAC2,CDCA3,PSMB1,SRPRA,PTPN1,CAMLG,ARL6IP5,DERL2,SVIP,ORMDL3,EDEM1,DHRS7,SELENOS,DEFB116,OSBPL8,USP15,SLC2A1,POR,ESYT1,PSMD7,UNC50,EMC2,IGF1R,NSDHL,MRPL22,LPCAT3,PSMA5,ERLEC1,SRPRB,TMEM33,CLEC2B,PREB,CCDC47,COMTD1,RAP1A,MTCH2,TP53,SERPINA1,SURF4,NFE2L2,NDUFS3,HEY2,SEC61A1,PSMA6,ATL1,SMAP2,SEC63,CPT2,BRAP,ATP5F1A,SLC6A4,HMOX2,PSMB2,CREB3,HFE,SYVN1,DERL1,RTN4,SPCS2,TEX264,CLU,HSPA5,TMUB1,TTR,CERS2,RPL4,GABRA1,HACD2,RABL3,FUT8,ARHGAP1,PDIA2,PDCL,TMX4,HSP90B1 |
| 5.379e-10 | -21.34 | ADARB1 (adenosine deaminase RNA specific B1) | protein interactions | 104 | 487 | 199 | 19454 | 5460 |
MIR106A,NOP53,EMG1,HADHA,CCDC86,NKAPD1,USP39,RAB6A,RPL19,TUBB,RPL7L1,RPF1,ACTB,RPS9,RPL37A,SNRPD1,RAN,ZNF22,MIR363,ZCRB1,FYTTD1,MCM4,MIR98,NOP16,SSRP1,RPS27A,SRSF8,SART3,RAB6B,NUP153,RPL29,FEN1,PPIA,RPL7,CCAR2,RPLP1,HP1BP3,RPLP2,MIR141,MIR7-2,MRTO4,PPP2CB,RPL8,THOC2,HNRNPD,RSBN1L,MIR1-1,HNRNPA1,AATF,BRIX1,RPL4,MIR7-3,GTF2I,NPM3,CCDC106,H2BC12,RPL26L1,RPLP0,ZCCHC17,LMNA,TOX4,MIR1-2,UBA52,SF3A1,RBFOX2,RPL22,UBB,SLC25A31,SCML2,RPL13A,UBE2I,PRKRA,EIF2AK2,TUBA1B,MIR145,NONO,RPL26,MDC1,RPS13,NOC4L,NKRF,TCOF1,SLC25A10,LLPH,RPL15,EEF1A1,TAF1D,RPL35A,PRR3,ACTA2,RPL12,MIR34A,MPHOSPH10,SLC2A1,SPATS2L,GRSF1,MOV10,STAU1,FXR2,DDX5,SF3B1,HSPA8,MRPL12,EHHADH,RPL27A,CBX5,GTF2F2,MIRLET7B,VDAC2,H1-1,NSA2,RPS26,ELAVL4,FTSJ3,H2AZ2,HNRNPAB,HNRNPC,HNRNPDL,RPL28,MIR155,RUVBL2,MIR206,TOP2B,MIR9-2,RPL31,RPL18,GLE1,RPS7,MIR222,TUBA1A,TRMT1L,MIR9-1,LYAR,SNRPA1,RPS10,HNRNPL,WDR82,SRSF1,SIN3A,MIR140,DDX1,MIR221,MIR31,H2BC17,NGDN,MIR29C,RPL6,WWP2,MIR143,DDX50,HSPA5,WDR3,KDM1A,HNRNPH2,NBN,NLE1,DDX46,RPL27,ZNF770,TFIP11,H2BC11,GTF3C4,MIR34B,SRPK2,RSL24D1,MACROH2A1,ZBTB33,PSPC1,ZSCAN25,H2BC9,RPL7A,RPF2,SMARCA5,RPL17,H2BC14,MIR16-2,MIRLET7C,IMP4,HNRNPK,MIR9-3,RPL3,MIR200A,RBM34,H2AX,STRBP,IMP3,SURF6,DKC1,TMPO,MIRLET7G,IFRD2,RPL32,MRPS9,EEF1B2,SYNCRIP,RPL10A,NOL12,CDK12,SNRNP70 |
| 5.401e-10 | -21.34 | regulation of tumor necrosis factor production | biological process | GO:0032680 | 189 | 96 | 18204 | 5365 |
TIRAP,MIR708,ACP5,MIR105-1,SPHK2,JAK2,OAS1,DEFB114,MIR488,ARG2,MIR206,TLR2,CD14,GHRL,MIR657,CCR2,DICER1,CCL19,MIR130A,MIR144,IL10,MIR101-1,CX3CL1,IL1A,VSIR,ADIPOQ,IGF1,CD2,SELENOK,LY96,TMEM106A,GSTP1,CX3CR1,MIR920,FCGR2A,TNFAIP3,DHX9,PTPN22,HMGB1,SYK,CLU,SELENOS,MIR361,PYCARD,AGER,FCGR2B,NFKBIL1,MIR98,MIR204,MAVS,TYROBP,RIGI,TICAM1,RAD21,TLR1,CHRNA7,CD36,MIR195,IL23A,IL4,MYD88,GPNMB,SETD4,IFIH1,TSPO,PIK3R1,TLR9,LILRB4,PSEN1,MIR149,LILRA2,IFNG,IL12B,AKAP12,MIR185,TLR3,CD47,FOXP1,HSPB1,CLEC7A,FRMD8,IL6,LILRB1,ANGPT1,FOXP3,MIR132,DDT,CCL3,MIF,SASH3,TRIM27,LEP,TLR4,IFNGR1,MIR140,PTPN11 |
| 5.496e-10 | -21.32 | BRCA1 (BRCA1 DNA repair associated) | protein interactions | 672 | 1234 | 442 | 19454 | 5460 |
COPE,JUNB,UBE2L3,UBB,ENO1,CTNNA1,RPS12,MSN,TRIM27,CDC73,SMAD2,AP2A1,DHPS,HSPA14,RACGAP1,BRAP,PIAS1,RPA3,ANAPC16,PICALM,GOLGA5,DCTN4,DCTD,RARS1,HNRNPH3,SF3A1,CCNA2,CDK7,CGAS,THOC1,CDK9,SMAD3,RPL12,TNKS,RB1,MOV10,ATP1B1,DAG1,FN3KRP,NSMCE3,HUWE1,EGR1,NKRF,TCOF1,RPL23A,DHRS7B,POLR2G,CCT5,EXOSC8,SPCS1,LGALS3,MED17,TRIM46,TUBB,EIF4A2,JAK2,RPS9,YWHAZ,BRCA1,FAM83A,RMI1,ILK,RPS5,HSP90AA1,PYCR1,NFYA,ATF1,MAP3K21,SRI,CMAS,EXD2,DHX15,EGLN3,PSMB5,RPL9,RPL8,RPLP2,BRD9,COTL1,HNRNPD,BABAM1,PIK3R1,ZNF207,HNRNPA1,ASF1A,RAD21,FANCG,SSRP1,PSMD12,HNRNPA2B1,HSPD1,HECTD3,PCNA,NME1,SART3,RPS11,POLR2D,POLR2C,NAA15,VDR,RPL29,JUN,CHMP5,MAP3K3,STAT5A,DYRK1A,MACROH2A1,CSNK2B,STN1,UBE2E3,ATP1B3,CDKN2AIP,RPL7A,CCNB1,SMARCA5,CARS1,AKT1,ARHGAP21,FBXO44,GRPEL1,PML,NBN,BAP1,RPL27,PGK1,GTF2H4,CAND1,MYL12A,ALYREF,UBE2N,RPL32,ACSL4,SLC39A10,H2AC4,RPL24,SMCHD1,MAP4,USP2,GAPDH,TPM3,HNRNPK,CSE1L,NUP107,PSMA5,AKAP12,PDE12,RPL17,TNKS2,DHX9,PCMTD2,CBX3,CDK8,DDX42,RAD1,TP53,RPSA,STAT1,MATR3,APEX1,ESR2,RPL10,CBX5,VEGFA,MCPH1,PRMT5,PSMD14,RPS6KA4,CCT2,MDH1,RCL1,SERPINH1,LDHB,HNRNPC,HNRNPAB,CREBBP,CNRIP1,MYC,PSMD1,RMI2,PHB2,EEF1G,TRA2B,FXR2,NDUFS2,DDX39B,DDX5,SF3B1,GTF2IRD1,NUFIP2,SNRPD3,SUMO2,HNRNPL,CCT7,HSP90AB1,RPRD1A,STX5,DDX1,RAB5C,RPL6,IFI16,CTNNB1,XPO1,RUVBL1,PSMA1,HNRNPF,TFG,RPL31,EWSR1,TUBB4B,RPS23,SMARCB1,ETFB,DHX38,RPS7,NUP37,EEF2,SNX3,LDHA,UBE2I,TRIM24,GANAB,PRKRA,SEC13,CDC16,KPNA6,AR,PPP1CC,GMPS,RUNX1,RPL4,EIF5B,GTF2I,AATF,SQSTM1,HSP90B1,LMNA,JUP,CDK1,FAM161A,CCND1,PSMC4,RPS14,POLR2I,TOP1,PPP1R18,RCHY1,ETV6,SEC23A,PSMD7,MED21,CRBN,TOPBP1,SSX2IP,NFKB1,SNAP91,GTF2E1,SEM1,MSH6,EIF3E,MDC1,RNF20,RPS13,OLA1,TFPT,ZC3H11A,SEPTIN7,SRP72,RAD23B,APEH,ILF2,PPME1,SERPINB9,RPL15,DDX39A,RPL35,RBBP4,RAN,FAU,RPL37A,LMNB1,RIT1,SP1,CUL2,MRM2,MCM3,MCM4,SKP1,PSMC1,SPATA4,THOC3,PCLAF,LMO4,EHD1,PPP1CB,CCAR2,RPL7,SPTAN1,OS9,NPC2,ERLIN1,WDR6,RPLP1,HP1BP3,DDX23,UBE2D1,RPL23,DPY30,PSMD3,PRPF19,CLPX,PRDX1,MAP3K14,ZBTB14,RBBP7,RFC2,MCM6,AP1M1,RPS24,UBE3A,JAK1,EZH2,ACO1,E2F4,MARCKSL1,NUP153,ADRM1,BUB3,NMI,PSMA6,CREB1,RPS3,DCLRE1C,PSMC5,DNAJC10,EIF3G,ANAPC4,MORF4L1,NCAPG2,KDM1A,UBE2K,HSPA5,MARS1,HNRNPH2,ZNF326,RPRD1B,RPA2,TRIM36,ACACA,SUMO1,UBE2W,SPTBN1,GTF3C4,CCNH,RPS16,CDC5L,SLAIN2,EEF1B2,SYNCRIP,LCMT1,TRIM45,PREP,BECN1,TUBG1,POLB,SMAD4,RPL10A,RPS2,XAF1,ACOT8,KARS1,KLHL22,CSNK2A1,KPNA2,CAPZA1,MNAT1,TCEA2,RPL3,NFE2L2,MRPL36,TFRC,PSMC3,CDK4,TNRC6C,ZMYM3,H2AX,RPAP2,SNRNP40,PSMD6,TRIM29,PSMD4,DES,PHF12,GTF2F1,TSEN54,GCC1,RBBP8,THOC6,CDKN2D,CDKN3,STAU1,UBE2D3,HNRNPA0,XRCC5,RFC4,EP300,HSPA8,CTBP1,PLAA,RPL27A,ELK4,DYNC1I2,TCP1,FAM98A,PGR,EIF2S1,ELK1,SRSF1,CEP57L1,FAAP100,EED,ZHX1,FKBP4,FOSL2,IKBKB,DRG1,HSPB1,UBE2E2,GSTM3,RWDD4,HNRNPDL,RPL28,PABPC1,TOP2B,CCT8,RUVBL2,RPAP3,SMNDC1,RPL18,MTA2,ARFGEF1,SUPT5H,KIF2A |
| 5.547e-10 | -21.31 | positive regulation of transport | biological process | GO:0051050 | 844 | 330 | 18204 | 5365 |
SDCBP,CACNB2,SDC4,CD47,MDM2,PGRMC1,DYNLL1,NLGN1,TMEM30A,IFNG,RAB8B,SCN1B,P2RY12,OAZ3,MEF2A,MIR1-1,CLEC7A,VPS4A,NCBP2,OAZ1,IL13,EHD1,P2RY1,FGFR1,GABBR1,NRDE2,MTMR2,STAC3,SGIP1,CALY,SRC,ADORA1,PPID,ANGPT1,SCAMP5,HSPA8,CBLL1,HOMER1,PTPN11,THY1,STX18,TM9SF4,ATF4,TLR4,APLNR,HNRNPK,FASLG,LEP,LRRC8A,LGALS3,COX17,NFE2L2,SLC6A4,IL15,C1QTNF1,PRELID1,MECP2,SLC38A1,B2M,VEGFA,NF2,OSBPL8,CHRNB2,TSPO,RAN,PIK3R1,MLC1,PIK3R2,JUP,AMIGO1,GSTO1,OPRK1,STIM1,PPARG,BORCS5,CAMK1,SFRP4,STC1,ACTB,TNF,ADIPOQ,APBB3,CX3CL1,CACNB3,SMAD3,SCN3B,PPT1,PRSS8,XCL1,CD63,AVPR1B,KLRC2,FCGR2A,VMP1,H1-1,CLTRN,VAMP7,LACRT,CLU,SYK,MBL2,ZDHHC8,CXCL12,CTDSPL2,VPS28,HFE,STX1A,CDK5,GOLPH3L,NKX3-1,FCGR2B,S100A8,TESC,OAZ2,S100A10,PRR5L,TRIM46,STK11,PYCARD,STAP1,SELENOT,MAP2K6,NHERF1,CXCL10,NPSR1,VAMP2,ATAD1,HCLS1,SYNGR3,CCL2,SPHK2,LRAT,TMSB4X,SYBU,IL15RA,CHRM3,DRD1,RAB31,TERT,PLP1,FGF13,GNA11,SRI,CD38,CD2AP,CFTR,MIR17,MIR183,TLR2,G6PD,AZIN2,NLGN2,RAB5A,SLC12A2,CNTN1,TBC1D5,C2CD2L,TMEM97,ARF6,CCL19,PICK1,SFTPD,EDEM2,CCR2,F2,FEZ1,CASK,KCNC1,CXCL9,KCNB1,CCL5,ACSL4,MIR223,FGR,RNASEL,IL2RB,HCRT,FCER1G,ATP1B3,BAX,EFCAB7,AHCYL1,CREB1,CDC42,PPIA,BGLAP,PTGES,KCNJ2,AKT2,RASL10B,RAB9A,PRL,PDCD5,MIF,CCL3,INPP5K,CA2,TRPC1,CDK1,APLN,DMAP1,CLIP3,HSP90AA1,FLOT1,SNAP25,PARD6A,VEGFC,FGF12,ACHE,LYAR,CHMP2A,CAV1,SAR1B,MAVS,EDNRA,MIR210,SNAPIN,UCN,NDUFA4,CD36,AP2M1,CAV3,PCK2,PLCB1,RBM22,NOS1AP,CNKSR3,HDAC3,MLLT6,ILDR1,TACR1,SLC38A3,RGCC,IL4,CREBL2,LILRA2,SYT4,SFN,MIR21,LPCAT3,AP2A1,ARPP19,ATP2C1,INHA,PSEN1,CD81,NFKBIA,IGF1,EP300,PDCD10,ABCB1,IL1A,CHP1,TGFB2,FCN2,BOK,CALR,OSBP,GH1,RAB3D,BAK1,RAB29,SLC1A2,HYAL2,CXCL11,KCNMB1,TF,IL2RG,OXTR,RETN,SLC6A1,RAB3B,PPP3CA,WASL,VAMP8,AKT1,GSTM2,DHX9,TGFB3,SPP1,IL1B,VPS4B,ITGA2,ADRB2,GREM1,PFKFB2,SMAD4,OR51E2,PPP3R2,ATP8A1,CHRM1,JAK2,EDEM1,CD151,STXBP1,TSG101,NR1H2,ACTN4,PCSK9,PLA2G5,MCHR1,PRKCB,CCR1,PRKCE,HGS,KCNIP2,GSK3A,SLC4A8,FCGR1A,BAD,RAB27A,AZIN1,XBP1,RIOK2,MIR20A,GHRL,CCL21,CD14,BAG3,MIR206,ANP32B,CBL,ATP5IF1,ATP1B1,PLAA,SOD1,CARTPT,MSN,DLG1,RAB3A |
| 5.671e-10 | -21.29 | BAG3 (BAG cochaperone 3) | protein interactions | 9531 | 615 | 242 | 19454 | 5460 |
DNAJC5,GORASP2,ST13,EXOSC1,IGF2BP1,ZBTB38,RC3H2,GNAO1,PSMC5,ZNF655,PSMA6,SRPK2,ELMO1,GMDS,OR10G3,CFTR,HSPB6,CAPN1,UBE2M,HSPB2,PGK1,RNF113A,TNFAIP1,BAP1,UGDH,PML,HSPA5,BNIP3L,UBE2K,AIF1L,LITAF,KDM1A,API5,RPS2,AGPAT1,MAP4,TRAPPC2L,MCL1,PDE9A,UBE2G2,UBE2N,NDUFB4,CYSTM1,CPNE1,FZR1,SNN,TMSB10,TMEM252,KBTBD4,RPSA,SPRY1,PSMC3,GNAI3,PSME1,GSKIP,CAPZA1,NEDD8,PSMA5,HNRNPK,NETO1,BAG3,MLF2,MYC,PBLD,GFUS,DNAJB6,ZMPSTE24,LAMTOR1,ATG3,FBXW11,SF3B4,DOK4,LMBR1L,NFKBIB,GLRX2,GSTM4,GPC4,ZNF428,TOM1L2,SSBP2,TIMM10,PSMB3,GH1,CTBP1,UBAC2,HSPA8,P4HA2,RAB5A,ARRDC3,NANP,CD40,PEBP1,YWHAH,YWHAG,MDFI,GSTM3,DDX1,HSPB1,YWHAB,GSTO1,AK2,NRSN1,S100A8,SPINT2,PSME2,KCND2,GSTA1,HSP90AB1,MACROD1,CCT7,RAB1B,DBR1,CDK17,LSM5,SOX2,ISG15,HELT,PPIL3,SNX20,CRKL,METTL21A,RAB4A,DNAJB4,LDLRAD4,RUVBL2,EWSR1,FAM168A,S100B,PABPC1,PSMA2,VDAC1,XPNPEP1,RUNX1,FBXO7,AAMDC,SEC13,PAIP2,HERC4,MAPRE1,RTRAF,CMBL,TRIM27,CFAP298,RPS12,PCP2,GAB1,CCNF,STUB1,ENO1,UBE2L3,NDP,COPE,DENND2D,TPT1,SLC35E3,CDK1,CTDSP1,CLK1,FLCN,SQSTM1,ARPC2,DVL2,CSTB,YKT6,SLC7A1,HDAC6,PSMB1,CDCA3,SMAD3,AIFM1,NAP1L5,G6PD,GSTA4,TMEM126A,CPNE2,RAB1A,OLA1,RIGI,EIF4EBP2,SEM1,CNOT7,RPS29,GALE,PYCR1,DPP10,HSP90AA1,BAX,YWHAZ,MAT2B,EIF4A2,STARD7,PDLIM3,ACTB,SIAH1,TMEM174,LYZL4,NDUFA5,FKBP1A,RTF2,CRYAB,NUBP2,TTC1,PSMA3,FAM168B,WBP2,NT5C3A,CSRP1,PSMC1,SKP1,UCHL3,CCDC186,PAFAH1B2,HSPB8,ATG7,UBXN6,PSMD3,CDKN1B,NQO1,LRATD1,DNM2,CBFB,PSMB4,PSMB5,WDR37,TPD52,DLG3,STK16,DOHH,EZH2,TTC32,GDI2,CTSA,CHMP4C,BAG2,ZYX,NEK9,SLC25A5,PSMD12,MCM6,COPS4,G3BP1,ETFA |
| 6.115e-10 | -21.22 | MAGOH (mago homolog, exon junction complex subunit) | protein interactions | 4116 | 243 | 113 | 19454 | 5460 |
ERH,RPL10,RPL19,ESR2,MATR3,ACTB,SNRNP40,TSN,SNRPD1,SNRPD2,PRMT5,RPS9,RAN,RIT1,FYTTD1,CHTOP,LMNB1,SNRPB,MYC,HNRNPC,SAP18,SRSF2,TRA2B,SF3B1,HSPA8,EP300,SNRPA,PYM1,DDX39B,NKAPD1,UPF3B,EIF4B,H2AC1,RPL27A,WDR77,SRSF10,DHX15,HNRNPL,SNRPD3,RPL7,SPTAN1,RPL8,SRSF1,PPM1B,TRA2A,PRPF19,PRDX1,RPL6,SRSF4,RPL28,SSRP1,KRAS,HNRNPF,JAK1,SRSF8,SRSF7,RTCB,RPS24,SLC25A5,SCYL2,RBM3,RPS11,RPL18,EZH2,CHMP4C,E2F4,UBB,SRPK2,MAGOHB,RPL13A,RPS3,EIF4A3,MAPRE1,UBE2H,CASC3,RPL26,CEP70,STK38L,RPL7A,STK38,RBM22,FBXW7,RPL4,HNRNPH2,TFIP11,DYRK2,RPL26L1,H2AC7,SPTBN1,SF3A1,CDC5L,CWC15,CGAS,TOP1,ALYREF,RPS2,SNRNP70,CHCHD1,RPL24,DPP4,SRSF12,CAPZA1,RPL17,CDC40,HNRNPK,RBCK1,THRAP3,RPL3,MAP1B,SNIP1,ILF2,EEF1A1,RPL15 |
| 6.196e-10 | -21.20 | ENO1 (enolase 1) | protein interactions | 2023 | 529 | 213 | 19454 | 5460 |
NAB1,KRAS,FKBP2,SUPT5H,EEF2,SOX2,TUBA1A,ISG15,MOB3C,FAM136A,FABP5,EED,SUMO2,SUMO3,HSP90AB1,CCT7,WWP2,IFI16,GSTM3,ACTR3B,DDRGK1,PPIB,PPFIBP1,AGR2,YWHAB,CBL,GIPC3,DDX39B,HSPA8,STAU1,EMC1,UFL1,ACAA2,PPT1,PIH1D1,IRF2,TRIM44,MCPH1,TAGLN2,TCAP,ESR2,DES,ATP6AP2,MORC4,PPP5C,CBX5,LDHB,MYC,BAG3,BTF3,PSMD14,CKB,BHLHE40,ATP5PF,MAP1B,TOMM40L,HNRNPK,MPST,MEPCE,INSIG2,H2AX,GLRX5,TFCP2,RNF8,EEF1B2,GATAD1,CD4,AKR1B1,MIF,IFRD2,CAND1,PLG,STX6,PGAM1,GAPDH,COPS5,MED29,BAP1,CCDC65,PRDX6,HSPB2,PGK1,BCL6,CFTR,NDUFAB1,IDH2,RPA2,ACACA,LUC7L3,HEXIM1,UBE2M,GSTP1,SLC25A39,PPP2R5E,PITPNB,HEY2,TXNDC12,KCTD9,SRC,SLC25A1,AKT1,CFL1,ENDOD1,SPOP,UBE2H,MT3,UBE3A,VPS26B,SRSF7,HINT2,ZC3H7A,PCNA,TRIM37,TRIM26,E2F4,ACO1,RAF1,DPH5,FEN1,HSDL2,B3GNT2,FAF2,CHMP4C,NTN4,EZH2,CYB5B,PHB1,GATD3,SNX1,DHX15,PPIA,PRPF19,PDIA3,HNRNPA1,KDM2A,HNRNPD,AHSA1,WBP2,PSMA3,RNF10,TERT,SRI,UCHL3,FKBP1A,ARCN1,CYB5R3,ENO2,TENT5C,LGALS3,CLIC4,CUL3,CUL2,ACO2,SMARCE1,PDE4B,BRCA1,YWHAZ,MYO6,RIT1,HSP90AA1,FAF1,TAGLN3,HINT1,HSD17B10,EMC2,ERG28,SNAPC3,HSPE1,HUWE1,MDC1,PRDX4,FBXO25,CDC42SE1,FBP1,PGM1,PRNP,POLE3,EMC4,CALR,HDAC6,NME2,FBXO34,RPA3,INPPL1,SOD1,GPX4,MTDH,CLK1,FBXW7,PMP2,SF3A1,ATG16L1,RBMS2,HSP90B1,METTL14,LMNA,UBAP1,HNRNPH3,CCNF,STUB1,MSN,NDN,LDHA,PNP,TXN,DDAH2,VIRMA,AR,IVNS1ABP,DEDD,FKBP1B,CA2,CDC73 |
| 6.239e-10 | -21.19 | UBE2N (ubiquitin conjugating enzyme E2 N) | protein interactions | 7334 | 315 | 139 | 19454 | 5460 |
CDK6,RNF128,UBE2N,AIFM1,CAV1,CDC5L,MDM2,SHPRH,CAND1,DCUN1D1,H2AC4,MUL1,BCL10,PC,IGF1R,RNF167,DDR1,ARF4,RBCK1,TRIM63,RNF115,UBE2V1,GNPNAT1,HADH,MAP1LC3B,TP53,KIF1C,RNF8,RNF181,RAD23B,TOPORS,ACOT13,ACTR2,ZNRF1,TRIM27,CAB39,RNF122,CCNF,STUB1,UBB,ADRM1,TRIM54,USP14,DNAJC8,BFAR,CCNB1,TRIM32,TNFAIP3,UBE2H,PTTG1,DTL,RC3H2,TRIM23,DERL1,MNS1,IDH3A,TXNDC17,NBN,RPA3,SOD1,HELLS,FBXW7,HMGB1,UBE2K,EIF5B,MYL12B,TPT1,CHIC2,SF3A1,MYLIP,ACACA,HEXIM1,IDH2,RNF103,RPA2,RAB11B,PPIA,TRIM15,CTNNB1,ZNF207,TRIM34,SIAH2,MARCHF5,PDIA3,HSPB1,CBL,TST,STAMBPL1,TRAF6,PEDS1,RNF152,UBE3A,TRIM11,TRIM21,ZYX,SAR1B,PELI1,KRAS,TNF,TRAF2,ISG15,E2F4,UBL5,RAF1,FEN1,RNF126,CHMP4C,EZH2,PLS3,UBE2S,SNRPB2,UBE2V2,SIAH1,UFD1,BAG3,PCCB,PRPF31,RNF40,CUL3,LDHB,RIT1,NTRK3,HSP90AA1,BRCA1,PELI3,PMAIP1,BIRC2,TRIM5,ATP5F1E,PEBP1,RNF11,IL1B,RNF5,NEK7,MRPL12,STXBP1,RNF182,PIH1D1,PPT1 |
| 6.278e-10 | -21.19 | NDUFAF4 (NADH:ubiquinone oxidoreductase complex assembly factor 4) | protein interactions | 29078 | 179 | 89 | 19454 | 5460 |
CCNF,CTNNA1,UBE2H,DNAJC19,SYP,CHCHD4,TUFM,NDUFB10,POLDIP2,CRYZ,SLC25A51,GFM1,TMEM126B,NDUFC2,BAP1,MAIP1,RPA3,MTRES1,RPA2,TIMMDC1,ARF6,AIFM1,PTPN1,SSBP1,COX4I1,CHCHD1,TMEM70,GRSF1,FASTKD5,DNAJC30,ABCE1,DHX9,GFM2,NDUFS3,MAP1LC3B,APOO,AURKAIP1,METTL15,MRPL11,NDUFAF4,PARL,MAD2L2,FBXO22,S1PR4,TACO1,CCDC90B,MTG1,HTRA2,LAMTOR1,AUH,MTG2,PMPCA,HSCB,NDUFS2,PHB2,ATP5F1E,AKAP1,NGRN,CXCR4,EXD2,NDUFA5,FEM1A,OTULINL,TIMM29,NDUFAF3,RAMP3,EGLN3,LRRC61,NDUFS8,COX14,RMND1,DHX15,GATD3,FAHD1,DUSP6,MRPS26,POU5F1,ARMC8,RHOG,MTRF1,IMMP2L,HNRNPF,HINT2,COX8A,NDUFB5,HSPD1,STK16,NUDT19,PDHA1 |
| 6.315e-10 | -21.18 | OSBPL8 (oxysterol binding protein like 8) | protein interactions | 114882 | 265 | 121 | 19454 | 5460 |
ESR2,USP5,BTG3,FBXO22,SEC61B,S1PR4,LMBR1L,BAD,NTRK3,RHOB,YWHAZ,LAMTOR1,GLT8D2,CUL3,RAB11A,TMEM38B,PXMP2,CHRNA7,STX7,RXFP2,RER1,TMED3,UFL1,OR1M1,RAB5A,HADHA,PIH1D1,FAM8A1,VAPB,SDC2,RND2,OTULINL,SEC62,PGRMC1,SYK,ERLIN1,EGLN3,RHOH,SPINT2,GJA1,RAB35,RB1CC1,RHOG,DDRGK1,EMC6,YWHAH,YWHAG,RAB5C,IFI16,LAMP2,UBXN6,KRAS,SLC2A8,TAS1R2,TMT1A,OTULIN,RND3,RAB4A,STIM1,RPN1,ERLIN2,DNAJC25,RAF1,VIRMA,SEC63,SMURF1,RHOJ,COPE,CSNK2B,OPTN,PSPC1,DNAJC19,DNAJC5,VAMP5,RAB9A,DERL1,SQSTM1,RTN4,SYVN1,PRKCB,SIRT7,RPA3,RHOU,TEX264,AVPR1B,SSR1,FGFR1,LMNA,RPA2,ST7,CDC42,TPRA1,ATG16L1,LMAN1,TMPO,STX6,EIF2B5,SNAP25,DNAJC1,ARF6,FZR1,ARL4D,RAC2,HSD17B11,EEF1AKMT3,PTPN1,FAM187B,ESYT1,P2RY1,TMBIM6,HDAC6,CSNK2A1,EMC4,DPP4,FKBP8,MDC1,RAB3B,CAMKV,IGF1R,RAB27A,DISC1 |
| 6.330e-10 | -21.18 | ARRB2 (arrestin beta 2) | protein interactions | 409 | 441 | 183 | 19454 | 5460 |
HSPA8,SF3B1,DDX5,ARRDC3,XRCC5,HNRNPA0,SLC31A1,BOLA2B,ADRB2,EIF4B,MAP2K1,PRMT5,PHF21A,DLG4,NFKBIA,STAT1,MANSC1,MYC,HNRNPC,H1-1,OXTR,POLR1B,H1-10,ADRB1,RPL31,PABPC1,RPL28,RPS4X,UTP25,HNRNPF,TUBA1A,RPS7,EEF2,ZRANB2,RPL18,HGS,KLHL12,TUBB4B,NFKBIL1,ADGRG1,HSP90AB1,HNRNPL,SUMO2,YWHAG,XPO1,YWHAH,RPL6,RAB5C,DDX1,YWHAB,H2BC17,HNRNPH2,ARHGEF6,HSPA5,KDM1A,STK38,CDC42,SPTBN1,CAPN1,SUMO1,KCNAB1,CSNK1A1L,CYTH1,RPS3,SRC,SRPK2,CFL1,RPS17,PTGER2,ARHGAP21,AKT1,RPL7A,IGF2BP1,CRHR1,UBE2H,RPL3,MAP1B,EIF1AD,CAPZA1,CYTH2,TNFSF8,CAMKV,HNRNPK,H2AX,CENPM,CDK4,TAB2,NUPR1,CAPZA2,ALYREF,TMPO,DKC1,CPNE1,GRM1,CSNK2A1,GAPDH,CXCR4,G3BP2,WDR77,MYL6,EDNRA,FZD4,RMDN3,SNRPD1,SNRPD2,AP2M1,GPR37,ERH,GNB1,RPL19,TAB1,ACTB,RPL35,RPL7L1,MCM3,CUL3,SCYL2,HNRNPA2B1,RPS27A,AHCYL1,MAPK10,PPP2R1A,TULP3,NAA15,RAF1,GPBP1L1,RPLP2,PTGDS,RPLP1,PPIA,DHX15,SPTAN1,RPL7,HNRNPA1,MAP3K14,MED4,HNRNPD,PPM1B,TRAF6,PRKCB,DVL2,PRPF4,RPL4,CDK7,ATG16L1,UBA52,RPLP0,PAK5,SYT2,TMEM74,UBE2I,SPIN3,STUB1,CTTN,LURAP1,TNFRSF1B,CTNNA1,UBB,RPL22,TMOD3,RPL26,NONO,CSK,EMILIN1,AP2A1,IGF1R,PPP1R12A,TCOF1,RPS13,CTNND1,RIGI,PTGES3,THRAP3,EEF1A1,LBR,RPL15,RPL12,MDM2,CAV1,ARF6,RPL35A,BRD3,PTGER4 |
| 6.389e-10 | -21.17 | ATP5MG (ATP synthase membrane subunit g) | protein interactions | 10632 | 138 | 73 | 19454 | 5460 |
LMAN1,ILVBL,ATP5PD,OPRL1,ZBTB2,AIFM1,FOLR1,PHB1,OCIAD2,HSD17B11,YBEY,GATD3,RHOG,TMEM70,NDUFB8,TSPO,DDRGK1,ATP1B1,G3BP1,ATP5F1D,ATP5PF,SFXN1,HINT2,EZH2,RPN1,SLC25A20,STX12,TBK1,ATP5PB,MTCH2,MAP1LC3B,CYB5R1,ATP5F1B,CPT2,RHOJ,B4GALT3,ACTB,UQCRQ,VIRMA,ESR2,TACO1,CYB5R3,CCDC90B,SCAMP2,ICAM1,ATP1A1,UBE2H,AUH,RAB11A,ATP5F1A,USP14,STAU1,FBXW7,SSR3,RER1,PHB2,SAP18,STX7,RPA3,RHOU,ATP5MK,EXD2,VIPR1,HADHA,RPA2,ATP5PO,SSR1,SIGMAR1,GPR35,CAV2,CYC1,PRDX3,CFTR |
| 6.529e-10 | -21.15 | ACTC1 (actin alpha cardiac muscle 1) | protein interactions | 70 | 664 | 258 | 19454 | 5460 |
LCP1,RNF113A,PRDX6,HSPB2,PGK1,BAP1,DDX46,HEXIM1,TFIP11,RPA2,SDCBP,CD2AP,GTF3C4,CCNH,CAPN1,SPTBN1,PRKCE,CHMP5,DAPK1,DAPK3,MACROH2A1,PHAX,PSMC5,PSPC1,IGF2BP1,CHRAC1,CFL2,CFL1,SMARCA5,SUGP1,MNAT1,RPL17,CAPZA1,MEPCE,KPNA2,RPL3,SNIP1,NUPR1,PSMC3,GNAI3,TNNI3K,IK,DISC1,ARPC3,CAPZA2,TFCP2,ZMYM4,ACTR1A,WBP11,RPSA,UBL4A,SNAP29,CDC5L,MYL12A,ESD,TMPO,FZR1,ADD1,RPL32,RPL10A,TMOD2,CDK12,RPS2,SNRNP70,GAPDH,PPIL4,RBM17,DPP4,ENY2,EEF1G,PHB2,UFL1,SF3B1,GPHN,SMARCD3,DDX39B,PEBP1,MRPL12,RPL10,ESR2,NCKAP1,SNRNP40,ATP5F1B,TAGLN2,STAT1,GTF2F1,SF3B4,SMU1,DLST,ZHX3,RPS26,LRRC20,H1-10,CHTOP,CKB,CCT2,EPS8,PAPOLA,MPC1,MYC,RUVBL1,HNRNPF,PDIA6,ACTR1B,RUVBL2,MYO1B,CCT8,PABPC1,TAF10,ZRANB2,MTA2,SMARCB1,PLS3,EEF2,RPS7,ISG15,ERRFI1,CCT7,TCP1,SNRPA1,EIF2S1,RPS10,CORO1C,PRCC,HSPB1,MAGOH,YWHAB,TGFB2,DDX1,DDRGK1,YWHAG,PFDN5,SS18,MBD3,PIAS1,HMGB1,NUCKS1,GTF2I,H2BC12,PRPF4,RPA3,PRIM2,WTAP,RPLP0,METTL14,DCTN4,CDK7,SF3A1,PSMC4,SAP30BP,DUSP10,VIRMA,NDN,TMOD3,TXN,RPS12,RTRAF,CTTN,EIF4A3,USP14,DNAJC8,PPP1CC,KPNA6,ATP5F1A,RPL26,FBXO7,CAP2,MDC1,PTGES3,MSH6,RNF20,THRAP3,WASL,HINT1,SEPTIN7,RPL23A,TCOF1,ACTR2,DMAP1,ING1,CCT5,FBP1,CWC15,TMCC2,CDK9,RPL35A,ACTA2,RPL12,H2AZ1,CNN3,KIAA1143,PSMD7,HDAC6,GTF2E1,ORC5,CALR,FBXO30,SKP1,POLA2,CYFIP2,NUP50,CFDP1,HADHA,NPB,MYL6,MFAP1,H2AC1,ADNP,TASL,ACTL6A,RPL19,DYNLL1,ACTB,RPS9,ZMAT2,CPSF1,GNG12,PFDN6,RPS5,PFDN4,SP1,RHOB,YWHAZ,MYO6,SMARCE1,PRPF31,TRIM37,LASP1,DHX16,RBBP7,TNF,RPS24,PCNA,SCYL2,HSPD1,ZYX,NEK9,RNASEH2C,JPT2,SART3,SF3B5,NGB,GTF2E2,NUP153,ASPM,ACTN4,MARCKSL1,FEN1,DHX15,LRWD1,SPTAN1,RPLP1,BRD9,PHB1,RPL23,HNRNPD,DDX23,BCL7C |
| 6.571e-10 | -21.14 | Rnf183 (ring finger protein 183) | protein interactions | 76072 | 447 | 185 | 19454 | 5460 |
NDFIP1,PSMD4,TAGLN2,RPL10,VDAC2,CCT2,RPS26,SLC38A1,PSMA4,SLC30A5,PSMD1,BTF3,PHB2,EEF1G,STAU1,EMC1,GOSR1,LYPLA2,TMEM160,UBAC2,EIF4B,GOSR2,TOM1L2,TCP1,CCT7,STX5,XPO1,RUVBL1,PSMA2,HNRNPF,RPS4X,CCT8,TMEM87A,KDELR1,HGS,CRKL,CHMP5,STAT5A,EIF4H,PPP1R10,RPS3,PSMC5,SRP54,ATP1A1,GORASP2,HSPA5,RPL27,ARFIP1,SSR1,USE1,LEMD3,NTPCR,CD2AP,FCHO2,ARL6IP5,CAND1,TMPO,SLC38A2,LMAN1,CAMLG,RPL32,ADD1,MAP4,USP15,DHRS7,GPRASP2,SRPRB,CSE1L,TMEM33,AKAP12,CAPZA1,RPL17,SLC25A11,STX18,TFRC,SURF4,PSMC3,MTCH2,PREB,SNAP29,UBIAD1,DYNLL1,USP5,RPL19,FAM91A1,YWHAZ,MYO6,RPS5,SCFD1,VEZT,CDC123,NSFL1C,PSMC1,ATP5MK,PSMA3,TXNL1,SKA2,VAPB,ARCN1,ELOVL1,NOTCH2,PGRMC1,RAB6A,AGK,SNX2,SNX1,DHX15,CACYBP,PHB1,WDR6,RPL8,ELP6,PDAP1,EMC8,RFC3,PSMD12,NDUFA4,NEK9,ZYX,HSPD1,RPN1,VAMP2,AP2S1,STX12,MARCKSL1,ARFGAP1,ERLIN2,PPP2R1A,FAF2,RPL13A,DEK,FERMT2,TECR,CTTN,VAMP3,RPS20,ARFGAP3,HMOX2,DEPDC1B,YKT6,CHMP2B,DVL2,SQSTM1,H2BC12,RTN4,MTDH,SLC12A2,STOM,PICALM,GOLGA5,AP1AR,CDK1,PDCL,SEC22B,PSMC4,RPS14,RABL3,SLC35E1,KDELR2,MAPRE2,COG1,RPL35A,EHBP1,SRPRA,HACD3,RPL12,PTPN1,ESYT1,ECD,CNN3,TMEM199,ATP1B1,FARSA,TOM1,HUWE1,RPS13,CTNND1,TCOF1,SLC25A10,EMC2,SRP72,CCT5,CCDC47,TBK1,LBR |
| 6.571e-10 | -21.14 | ZBTB2 (zinc finger and BTB domain containing 2) | protein interactions | 57621 | 447 | 185 | 19454 | 5460 |
EHD1,NDE1,SLC25A3,RTF2,ATP5PO,CCDC86,COIL,FOXP2,ATAD1,SP1,LMNB1,SNRPD2,RMDN3,FAU,ZNF22,ERH,DYNLL1,RPL7L1,RBBP4,ERLIN2,MARCKSL1,EZH2,RPN1,MKLN1,SRSF8,MRPS11,SRSF4,MRPS17,FOXP4,SSRP1,ZNF592,RBBP7,TRIM26,TRA2A,PRPF19,RASSF8,MRPS26,PDCD10,ELP6,PHB1,MRTO4,SRSF10,NOP58,UQCRC1,GABARAPL2,EIF3J,UBLCP1,SF3A1,SAP30BP,MYL12B,RPL26L1,HNRNPH3,MACROH2A2,MRPS34,PICALM,CHMP1A,ANAPC16,TCEA1,NHP2,CHMP2B,MBD3,BRIX1,NTAQ1,RPL26,ZMYND19,ZNF687,PPIG,TEX19,STK24,PRKRA,ZBTB18,CAB39,UBE2I,PELP1,MAGOHB,LBR,MTA3,MRPL11,PPME1,SRP72,PPP1R12A,NKRF,SFXN1,ARF4,MDC1,MSH6,THRAP3,SUV39H1,MOV10,ATP5MG,FOXP1,KRR1,MRPS23,ZBTB2,TOP1,NCOA5,SF3B1,STK26,DDX39B,SAP18,MRPS7,FXR2,SRSF2,TRA2B,STAU1,PHB2,RPL39,SNRPB,CREBBP,NSA2,MRPS25,H1-10,SMU1,VDAC2,CBX5,FOXJ3,RPS7,MTA2,TAPT1,PICK1,TOP2B,CCT8,RWDD4,HNRNPF,VDAC1,ROCK2,XPO1,CTNNB1,BTF3L4,NGDN,BAZ1B,DDX50,RPL6,POU5F1,RIMKLB,EED,CHMP2A,CCT7,HMG20A,TTC9C,SUMO2,TCP1,LYAR,SNRPD3,SNRNP27,SUMO1,UTP15,ANGPTL2,STAT6,LUC7L3,QRSL1,ZNF326,RPS17,RPF2,SMARCA5,ATP1A1,MECP2,BICD2,MRPS28,RBMX2,CREB1,ROCK1,SRPK2,ZMYM3,UBL4A,MTCH2,TP53,BIRC5,MRPS18B,DHX9,ZBTB25,SRSF12,KPNA2,CMSS1,COX5A,AKAP8L,SNRNP70,RAP1B,SYNCRIP,MGME1,ALYREF,DKC1,TMPO,SURF6,CDC5L |
| 6.656e-10 | -21.13 | AK2 (adenylate kinase 2) | protein interactions | 204 | 161 | 82 | 19454 | 5460 |
FAHD1,AIFM1,SLC25A12,PLGRKT,COX14,HDAC6,COPS5,CRIP1,AGR2,NME2,IDH1,JAK1,COA4,ABCE1,BCKDK,TCOF1,CDKN2C,SFXN1,SCYL2,RIGI,IMMP2L,SAR1B,MEPCE,MX2,CDK20,ETFA,GUK1,HUWE1,HOXB1,TMEM205,GLRX5,ETFB,CDK4,RAF1,MSRB3,PDHA1,NUDT19,CAMK1,ACAT1,GSK3A,TSSK1B,OPTN,CCNF,PARL,SH3BGRL,SMURF1,TXNDC12,TENT5C,TRIM54,CTSB,TXN,BAG3,TUFM,AK3,MTPN,CUL3,CDKN2D,ACO2,UBE2H,FXN,HTRA2,PMAIP1,COX17,SOD1,PTRHD1,RPA3,BAP1,ABCC5,CRYZ,BCL6,MRPS7,SLC25A51,NF2,EMC1,NEK7,GABARAPL2,MRPL12,SLC25A3,UBE2M,ACAA2,SIGMAR1,RPA2 |
| 6.693e-10 | -21.12 | MTOR (mechanistic target of rapamycin kinase) | protein interactions | 2475 | 335 | 146 | 19454 | 5460 |
AKT1,TNFAIP3,ATP5F1A,RPL26,TUBA1B,METAP2,CCNF,PTEN,GANAB,PSMC5,RHOJ,MAP3K3,VIRMA,SUMO1,CFTR,HCST,RPA2,SHOC2,PRKCA,UBE2M,ZKSCAN1,SIRT7,NBN,PML,RPA3,SNAPC1,SQSTM1,FBXW7,STK38,EIF4E,LAMTOR2,EDEM1,MOV10,GNG2,LANCL2,BECN1,SMAD4,FOXP1,SMDT1,CD274,SYNCRIP,HRAS,RAC2,TOP1,SPPL3,ILVBL,TP53,RAP1A,COMTD1,TBK1,FBXO8,RAB1A,IGF1R,RPL23A,AKAP12,CD80,EIF4EBP2,TNFSF8,FKBP8,VPS16,SOCS2,SCN3B,SFN,GPR17,BTF3,RHEB,BRCA1,YWHAZ,PSMD14,ILK,MAF1,VMP1,HSP90AA1,NTRK3,NFKBIA,DPEP1,SCN2B,LMBR1L,MRPL13,TUBB,STAT1,GNB1,EFNA5,APLNR,PGRMC1,FAM234A,PRR5L,NPY2R,CCDC167,MAP2K1,FKBP1A,PIH1D1,KLC2,CD40,CXCR4,RAP2A,EP300,TERT,HSPA8,GPHN,STAU1,RP2,SLC31A1,NPTN,CMAS,SLC38A7,FAM174A,LAMP2,PDIA3,EIF3D,YWHAH,XPO1,YWHAG,TRAF6,IKBKB,RHOG,RPL23,BCL2L1,DICER1,YWHAB,HNRNPD,GNB3,SOSTDC1,RHOH,HSP90AB1,TRMT61A,MAX,TOP3B,TRAF2,TUBA1A,ASPM,CA14,CYB5B,RNF126,MTA2,CD83,GADD45A,RUVBL2,RABGGTB,PCNA,RUVBL1,SEMA4C,TRIM37,DCP2,RRAGB,KRAS |
| 6.693e-10 | -21.12 | SAR1B (secretion associated Ras related GTPase 1B) | protein interactions | 51128 | 335 | 146 | 19454 | 5460 |
APEH,ACADSB,PGM1,LBR,IL1R2,CENPM,RPL17,OLA1,SRPRB,HNRNPK,PC,HINT1,IDH1,RPL3,PSME1,NAE1,RPL24,NME2,GAPDH,GLO1,PGAM1,CIDEB,G6PD,CAV1,TMPO,SLC38A2,ESD,RPL35A,SEC23A,HSD17B11,UBE2N,SRPRA,LEMD3,ACACA,CARHSP1,GHITM,STOM,GOLGA5,HSP90B1,RPA2,CDK1,CFTR,SNRNP27,SEC22B,RPS14,VPS28,RPL4,SQSTM1,GFM1,MAVS,KIN,LSM12,ZBTB6,TMEM263,PPM1G,CALU,UBE2H,CDC73,PKNOX1,GLOD4,GORASP2,USP14,GMPS,SEC13,CREB3,MAT2A,RASL11A,VIRMA,UBA3,TXNDC12,EIF4H,LDHA,CFAP298,ABHD14B,GANAB,FRRS1,RPS3,TMEM14B,JPT2,CCR1,BZW2,GDI2,STIM1,EEF2,CBLN4,ACTN4,FAF2,PTS,ANP32A,SAR1B,ANP32B,TFG,RPL28,GCA,AP1M1,VDAC1,UFM1,PCNA,CCT8,TMT1A,RPL31,HSPD1,AGR2,FKBP4,AK2,PPIA,SNX2,TCP1,STX5,GATD3,PSMB5,FABP5,RPL8,AKR1A1,ATP5PO,CTBP1,TMEM115,ETF1,SEC62,OTULINL,PAFAH1B1,GINM1,LAP3,RNF11,PXMP2,YTHDF1,SLC31A1,GOSR1,AKAP1,XRCC5,MDH1,DNAJB6,GTPBP2,S100A11,SLC30A5,GSTM5,BTF3,JPT1,LDHB,CUL3,COPS7A,CLIC4,PRDX2,SEC61B,CYB5R3,FAM177A1 |
| 6.798e-10 | -21.11 | CTNNBL1 (catenin beta like 1) | protein interactions | 56259 | 195 | 95 | 19454 | 5460 |
RBM17,SPP1,SNRNP70,KPNA1,CXCL14,RPL32,FZR1,RPL35A,TOP1,SURF6,CDC5L,CWC15,TBK1,CENPM,WBP11,H2AX,IK,NUPR1,HAPSTR1,CTNNBL1,CDC40,H3C1,HNRNPK,KPNA2,MAT2A,CARS1,ATP5F1A,SPOP,SRPK2,ATG16L1,SF3A1,PPP1R8,SNRNP27,CREBZF,ZMYM6,RPA2,LSM2,STAMBP,SNAPC1,RPA3,SIRT7,RBM22,HMGB1,LDOC1,BCL6,PRPF19,ZCCHC10,ZCCHC9,CDC23,MED4,COPS2,BUD31,KCTD10,SUMO2,RAF1,MED9,PPP2R1A,SKA3,EZH2,SDHC,HNRNPA2B1,EWSR1,PRDM4,RPS24,ERP29,KRAS,G3BP1,CDCA7L,COPS4,CATIP,MYC,HNRNPC,CUL3,RNF40,PSMD1,PRPF31,GGH,SNRPB,BEX3,CYP1A1,PELO,POLR3B,SF3B4,PRMT5,RPS9,STAT1,SNRNP40,WDR77,MED23,MRPS18A,PSMB7,THAP2,SNRPA,HSPA8,STAU1 |
| 6.950e-10 | -21.09 | PDZD8 (PDZ domain containing 8) | protein interactions | 118987 | 424 | 177 | 19454 | 5460 |
KRAS,RPS4X,RPL28,PABPC1,RINT1,CYP2C9,RPL31,RAB4A,RPS23,RPL18,STBD1,TOP3B,RPS7,DNAJC25,RHOH,HNRNPL,RAB35,STX5,RPL6,RAB5C,LAMP2,DDRGK1,LRRTM1,STAU1,EMC1,UFL1,RPS28,XRCC5,DDX39B,RAB5A,DDX5,MIA2,RPL27A,SEC62,PSMD6,SNRNP40,MATR3,RPL10,ATP6AP2,H1-10,LAMTOR1,RPS26,FIS1,HNRNPC,ENTPD4,MYC,RPL39,RAB3B,SRPRB,HNRNPK,FKBP8,RPL17,DHX9,RPL3,TFRC,FURIN,RPSA,PREB,RPS16,DNAJC1,LMAN1,STX6,TMPO,RPL32,CAMLG,ALYREF,RAC2,RPL24,KCNJ10,SMAD4,RPL10A,MAP4,RPS2,DPP4,KARS1,RPS15,MARS1,EIF4E,TEX264,RPL27,RAB9A,CYP2C18,DERL1,SSR1,FGFR1,LEMD3,CDC42,RPS3,TLR9,EIF3G,RPL7A,SMARCA5,ST13,TMT1A,RPS24,STIM1,RPN1,MACO1,FAF2,RPL29,RPL7,RPL8,RPL9,RPLP1,RPLP2,GJA1,RHOG,RPL23,PSMD3,EIF3D,PXMP2,STX7,NUP50,VAPB,TOR1AIP2,H1-5,RND2,OTULINL,RPL35,RPL19,EIF3K,SEC61B,RPS9,RPL37A,LMNB1,PFDN2,CUL3,RAB11A,VEZT,THRAP3,RPS13,IGF1R,EMC2,RPL23A,SRP72,YTHDF2,CCDC47,RPL15,LBR,MAP1LC3B,RPL35A,ARF6,EEF1AKMT3,PTPN1,RPL12,SRPRA,HSD17B11,PSMD7,ESYT1,SLC25A46,EMC4,TMEM199,HDAC6,LAMP3,RPL4,YKT6,FADS2,SYVN1,HSP90B1,RPLP0,RARS1,SEC22B,RABL3,ST7,EIF3J,RPL13A,RHOJ,COPE,VIRMA,RPL22,SEC63,UBB,CIB2,RPS20,RPS12,PAIP2,HMOX2 |
| 6.983e-10 | -21.08 | OBSL1 (obscurin like cytoskeletal adaptor 1) | protein interactions | 23363 | 891 | 332 | 19454 | 5460 |
PRKRA,GANAB,RTRAF,TMEM74,ALB,PELP1,EIF2AK2,TNFRSF1B,FBLN5,ENO1,CTNNA1,TUBA1B,CTTN,EIF4A3,DEK,LDHA,RHOJ,ATP5F1A,TUFM,NONO,AR,AP2A1,NAPA,ARPC2,PRPF4,CXXC1,AATF,BRIX1,EIF5B,SF3A1,DDAH1,SEC22B,RPLP0,HNRNPH3,RPL26L1,PLAC1,MACROH2A2,LMNA,JUP,CDK1,PAK5,HSP90B1,SLC12A2,PWP2,SEC23A,PSMB1,RPL12,HACD3,H2AZ1,KRR1,ARF6,THOC1,TOP1,GRSF1,SPATS2L,DNAJC7,PSMD7,ZC3H11A,RPL23A,HSD17B10,NKRF,TCOF1,PQBP1,MDC1,ZSCAN5A,HUWE1,THRAP3,NOC4L,EEF1A1,LBR,PSMB9,CD2BP2,APOBEC3D,RPL15,JPH4,CCT5,ILF2,ACTR2,LRRC1,SNRPD1,RPS9,CPSF1,ZNF22,RAN,CHCHD3,RPL19,SNRPB2,RBBP4,RPL7L1,PRPF31,RFC5,MCM3,FAM219A,LMNB1,YWHAZ,EMG1,CCDC86,COIL,G3BP2,SKP1,NOP53,PRDX3,NOTCH2,MFAP1,SLC25A3,PSMB7,USP39,ATP5PO,H2AC1,HP1BP3,KRT8,RPL8,THOC2,PSMB4,PHB1,MRTO4,PSMB5,MYEF2,PPIA,SRSF10,EGLN3,DHX15,NUP35,NOP58,INA,RPL7,CCAR2,HNRNPA1,TRA2A,PRDX1,HMGA1,PDIA3,PSMD3,PRPF19,STOML2,MRPS35,HAX1,HNRNPD,RSBN1L,DDX23,WDR12,HBA1,PCNA,BAG2,SELENOP,SRSF7,HSPD1,SCYL2,ZYX,SLC25A5,HNRNPA2B1,MAEA,PPAN,PSMD12,MCM6,SSRP1,FLOT1,DHX16,G3BP1,PPP2R1A,ACTN4,NUP153,TULP3,RAF1,MTMR2,SNRPE,EZH2,RPN1,CSNK2B,MRPS28,MACROH2A1,PSPC1,PPP1R10,DYRK1A,IRF2BP1,MRPS21,ADRM1,RAB2A,RSPH1,PSMB2,RPF2,SMARCA5,RPL7A,IGF2BP1,UBE2H,CALU,MRPS16,HNRNPH2,EXOSC4,DLAT,DDX46,NLE1,HSPA5,KDM1A,WDR3,AGO1,SUMO1,TFB1M,HECTD1,LUC7L3,ZNF326,SYNCRIP,ALYREF,EPHB6,DKC1,TMPO,RBM42,CDC5L,GPRASP2,CSNK2A1,TMA16,POLR3GL,GAPDH,TPM3,CMSS1,RBM17,RPS2,FAM222A,RPL10A,AGPAT1,SMCHD1,ADPRH,SNRNP70,RPL3,DHX9,MRPL52,PSMB10,CAPZA1,NUP107,KPNA2,HNRNPK,WBP11,IMP3,STRBP,RPSA,TP53,GCHFR,CENPM,DDX42,CBX3,IK,RBM34,NEFL,ARPC3,CAPZA2,SMU1,MCPH1,ANAPC2,LMBR1L,MIDEAS,POLR2B,PSMB6,CBX5,ATP5F1B,TAGLN2,MATR3,PSMD6,SNRNP40,CUTA,CPSF2,SNRPB,HNRNPAB,HNRNPC,SERPINH1,CCT2,CKB,LAMTOR1,CIRBP,H2AZ2,FTSJ3,ATG3,CHTOP,H1-10,SF3B1,DDX5,DDX39B,SNRPA,XRCC5,FXR2,HNRNPA0,TRA2B,SRSF2,EEF1G,NUP62,TANK,PSMB3,ZC3H14,NCOA5,GRIK1,CORO1C,SRSF1,FUBP3,ANKRA2,LANCL1,HSP90AB1,COX14,HNRNPL,TCP1,SNRPD3,SNRPA1,PPIB,XPO1,PPFIBP1,UTP6,CTNNB1,BAZ1B,DDX50,RPL6,DDX1,HSPB1,RUVBL2,EWSR1,PDIA6,RTCB,TOP2B,PABPC1,CCT8,ABCF1,RPS4X,HNRNPDL,POLDIP3,PSMA2,HNRNPF,PSMA1,RUVBL1,KIF2A,TRMT1L,SUPT5H,ZRANB2,MTA2,RPL18,TUBB4B |
| 7.016e-10 | -21.08 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | REACTOME pathways | R-HSA-179419 | 74 | 49 | 10285 | 3229 |
PSMD12,PSMC1,ANAPC16,PSMA6,MAD2L1,PSMD1,PSMB2,PSMD6,ANAPC2,PSMB4,CDC23,ANAPC15,UBE2D1,PSME2,ANAPC4,PSMB9,SEM1,PSMA1,PSMC3,PSMD4,ANAPC11,CCNA2,RPS27A,CDC20,PSMB1,PSMD3,CDC16,PSMB7,PSMC4,PSMA3,PSMB5,NEK2,PSMC5,PSMB11,PSMB10,PSMA5,PSMA4,PSMB3,PSMB6,PSMA2,BUB3,CDK1,PSME1,PSMD10,PSMD7,PSMD14,UBB,CDC26,UBA52 |
| 7.023e-10 | -21.08 | RTN3 (reticulon 3) | protein interactions | 10313 | 156 | 80 | 19454 | 5460 |
RPA3,TSPAN15,SYVN1,RABAC1,DERL1,RAB9A,RTN4,SQSTM1,STK26,FXR2,GABARAP,PGRMC1,CDC42,SEC62,YIPF5,VAPB,LMNA,RPA2,FGFR1,GPR35,SIGMAR1,SSR1,TM9SF1,LMBR1L,CDIPT,SCAMP2,RETREG3,SEC61B,COPE,CCR2,REEP4,TAX1BP1,KDSR,RAB11A,HMOX2,ATP1B3,SMPD2,SPOP,PLN,REEP6,UBE2H,BACE1,TMT1A,PGAP4,RAB3B,TOLLIP,SACM1L,RIGI,TP53,GABARAPL1,RPN1,STIM1,PTRH2,UGCG,RAB35,PTPN1,HSD17B11,MAP1LC3A,RAC2,HNRNPL,DNAJC1,ARL6IP5,PLEKHF2,SNX1,DERL2,TMPO,RAB33A,MSMO1,FHIP1B,SLC25A46,TMEM208,XPO1,YWHAG,FAM241A,FAM241B,ESYT1,AGR2,TMEM70,CBL,YWHAB |
| 7.066e-10 | -21.07 | programmed cell death | biological process | GO:0012501 | 1087 | 411 | 18204 | 5365 |
BOK,NSG1,SGMS1,DIO3,VDAC2,PDCD10,EP300,PTRH2,NFKBIA,GPX1,CYFIP2,KLK5,CTSK,NPR2,VDR,BAK1,SLC1A1,CTNNB1,TNFAIP3,SIAH2,IL1B,DELE1,AIFM1,AKT1,WNT7A,SMAD4,GABARAP,PCSK9,PTEN,JAK2,STXBP1,BCL2L1,TUBA1A,DEDD,BAD,BCAP29,G0S2,KRT8,TMEM219,GSK3A,PRKCE,BLCAP,CDK5RAP3,KIT,MLLT11,FAS,CD14,HTRA1,XBP1,SIVA1,CRKL,RRN3,SOD1,TGFBR2,STK26,IL2,MSH6,PAK2,CAAP1,ACVR1C,PEA15,THOC6,GADD45G,ACAA2,RTKN,MMP9,AHCYL1,IL6,BAX,TRAF3IP2,STAMBP,TP53INP1,ERRFI1,VDAC1,DRAM1,MX1,HSPD1,PPP2CB,AKT2,DAPK3,PAK5,TRAF7,EDNRA,BCL2A1,NOA1,IFI27,ELK1,GPR65,CASP12,PMAIP1,BAP1,TIA1,MCL1,UBE2B,ZBTB16,RTN4,EMP2,TNFRSF1B,KCNIP3,MIR21,IFNA2,SFN,MSX2,PARP2,CSRNP1,SMAD3,LMBR1L,IFIT2,CD2,NAIF1,EGLN3,SELENOK,BIRC2,PDCD1,GPAM,TMBIM6,ACVR1B,RALB,SAV1,BFAR,NLRP1,CLU,CCAR2,STK11,S100A8,EAF2,NKX3-1,HINT2,PML,CHI3L1,IL2RA,MAP2K6,CRADD,KCNJ8,SPATA2,NFKB1,NAE1,CYP1B1,NDP,GADD45A,TLR2,ZDHHC16,GSKIP,DMPK,CD38,C1D,CD2AP,NPTX1,PPIF,NINJ1,PLAGL1,SYCE3,VPS54,IFNG,TCIM,DYNLL1,CD47,PIK3CA,TAF10,TMEM117,BIRC5,ETV6,MEF2A,THOC1,PDCD4,ROCK1,ANGPT1,TRIM35,G2E3,PPID,ADRA1A,FAM162A,SRGN,RB1CC1,SST,KCNJ11,FAIM,TNFSF12,FASLG,SQSTM1,PMP22,RNF41,PIK3CG,ATF4,TRIM21,ZMAT3,ARHGEF6,IVNS1ABP,PRELID1,MRPL41,TICAM1,CCAR1,BNIP3L,PPM1K,MIR29A,VEGFA,EI24,CD248,KDELR1,BMPR2,IRF1,BRMS1,DNAJC5,CUL3,PIK3R1,NR2E1,NBN,BEX3,TNFRSF9,AREL1,IFI16,PAK6,IL1A,TGFB2,POLB,PLSCR3,CRIP1,NOTCH2,KRAS,EMC4,SMNDC1,NUDT2,FGF10,GLRX2,FEM1B,DHX9,CEACAM5,ELMO2,HAND2,DDIT4,ING5,NLRP6,MIR29C,NCKAP1,PRKCB,FOSL2,LTA,SOX9,ERO1A,CTNNA1,BAG3,CSNK2A1,PAEP,ADAMTS20,CHST11,LTBR,FIS1,DICER1,SNAI2,TOPORS,BECN1,DLX1,DYRK2,RMDN3,TLR3,PEG10,ZFAND6,CRYAB,NUPR1,PLEKHO2,PPIA,DAPK1,SFRP1,FLCN,MAGEH1,GGCT,IER3,SNCB,MYC,CNTFR,CDK1,IL12A,BCL10,HNF1B,PDCD5,STK3,DAD1,RNF34,AKAP1,HSP90AA1,HEY2,IRF3,CDIP1,CAV1,EFNA5,TNFAIP8,MEF2C,TAX1BP1,CD28,CDKN2D,PIM2,GADD45B,BRCA1,MYD88,IFT57,ZMPSTE24,HTRA2,RPS27L,ATG9A,PSEN1,ARL6IP5,NLRP9,IGFBP3,IL10,MUL1,RAF1,CX3CL1,TNF,EDA2R,RPS3,PDIA3,TRAF2,MSX1,SLC25A4,TRAF1,CDK5,ELMO1,MINDY3,EPHA2,DFFA,DNAJC10,BCL7B,MZB1,PLEKHF1,RHOB,PYCARD,HRAS,CXCR4,ZNF622,CIDEB,ATG3,CDKN1A,RBM5,SH3GLB1,TOP1,CFDP1,INPPL1,PSMD10,NLRP2,CTTN,RB1,CITED1,ADNP,DAP,TNFAIP1,RNF152,CASP4,AIPL1,NLRP3,XAF1,MIR17,RNF144B,CXCR3,NEFL,PRKCA,MIEN1,BCL7C,PLSCR1,FOXC2,GAS2,EXOC5,ARF6,ALDH1A3,MAP1S,FKBP8,MAEL,CTSC,TP53,ERCC3,STK4,RRAGA,BLOC1S2,TNFSF10,MDM2,API5,UBE2D3,DDX5,MIR34A,FHIT,SOD2,MITF,CSRNP3,ADORA1,EMP3,PCGF2,PRDX2,ITGAV,DDIT3,IFI6,EVA1A,GHITM,JADE1,DNAAF10,TFPT,TMEM14A,SIAH1,GAPDH,HINT1,EPO,RAD21,CUL2,NR4A2,CLN8,IL7,NCSTN,FAF1,STK24,CDKN1B,HELLS,FATE1,LIPA |
| 7.209e-10 | -21.05 | CDC34 (cell division cycle 34, ubiqiutin conjugating enzyme) | protein interactions | 997 | 324 | 142 | 19454 | 5460 |
RAB8B,RAD21,RAB18,MCM6,GTF3C3,G3BP1,BAG2,TRIM21,CCT8,PTRH2,KDELR1,FBXL3,EEF2,FAF2,HSP90AB1,PPIA,CCAR2,TCP1,NOP58,RAB1B,FBXO32,RPL9,WDR6,CDKN1B,FKBP4,RHOG,RAP2B,XPO1,WWP2,RAB5C,RAB3D,PSMD3,UBE2D3,HADHA,HSPA8,ACAA2,RNF7,PPARG,KCTD12,PPP1CB,PGRMC1,EHHADH,ACTL6A,USP5,POLR2B,TRIM29,SIAH1,NFKBIA,CPSF1,SERPINH1,HSP90AA1,LMNB1,FBXW11,FAS,MCM4,MCM3,CUL3,CUL2,ACO2,MSH6,ARF4,FASTKD5,TMEM33,NEDD8,NUP107,PC,HINT1,SLC16A1,RAB13,RNF167,SLC25A10,RAB1A,GNAI3,ACTR2,TMEM165,ZNRF1,CBX3,PPARA,LBR,MAP1LC3B,PPIF,RAP1A,PREB,RRM1,CCDC47,SLC25A12,MDM2,CDK9,ARL6IP5,MYBL2,RAP1B,RPL12,STT3A,SRP14,HACD3,RAB3A,KPNA1,LANCL2,ESYT1,MUL1,USP2,TCEANC2,MARS1,HSPA5,FBXW7,SMC4,KDM1A,WDR3,RAB9A,MAIP1,DDX46,RAG1,LUC7L3,SAMM50,SDCBP,SPRYD4,PCK2,RPS14,SEC63,TECR,UBB,ROCK1,RAB14,GNPDA1,GANAB,CSNK2B,SYT2,CCNF,OPTN,PTTG1,XPOT,DNAJC10,STN1,ZFAND6,RAP2C,PPP1CC,GMPS,KPNA6,RPS17,FBXO7,CCNB1,NAA50 |
| 7.257e-10 | -21.04 | PSMA1 (proteasome 20S subunit alpha 1) | protein interactions | 5682 | 465 | 191 | 19454 | 5460 |
NMI,TRAF1,ADRM1,KCTD9,TRIM54,PSMC5,PSMA6,PSMG3,UBE2H,ATP1A1,TRIM23,PCBD1,CEP70,PSMB2,BCL6,GRPEL1,DERL1,TNFAIP1,EXOSC4,PSMG4,TRIM10,BAP1,ACACA,HEXIM1,RPA2,CFTR,PAAF1,CCNH,DDIT4L,CD274,USP15,PSMG2,COPS5,FKBP8,CAPZA1,PSMB10,MSANTD4,RBCK1,NEDD8,PSMA5,PSME1,MAP1B,PSMC3,GNAI3,CAPN2,SH3GLB1,GUCD1,HADH,DUSP1,TP53,PSMB6,PSMD6,MBL2,PSMD4,PRMT5,NFKBIA,VMAC,LMBR1L,H2AZ2,PSMD14,POMP,CCDC85B,PSMD1,LDB1,PSMA4,CDKN2D,LMO2,MYC,DDI1,SRSF2,HSPA8,GPHN,PIH1D1,MAP2K1,PSMB3,RPS10,RAB1B,HNRNPL,HOMER3,PSME2,CDC23,AGR2,DCTPP1,PSMA2,KRAS,PSMA1,PICK1,MYO1B,RUVBL2,CSTPP1,ZRANB2,PNMA2,TUBB4B,SOX2,ISG15,PPIL3,MIEF1,VIRMA,SH3BGRL,SH3BP4,YES1,TMOD3,COPE,TRIM27,HEXIM2,EIF4A3,CCNF,CINP,MAPRE1,YPEL5,XPOT,TXNIP,USP14,AR,FBXO7,ZMYND19,LDOC1,HMGB1,DESI1,NUCKS1,SYVN1,PRPF4,PPM1G,RPA3,DVL2,WTAP,DCTD,CDR2,GRM2,HSP90B1,CHMP1A,UBA52,ATG16L1,PSMC4,TNR,PSMB1,SEC23A,SRP14,SSX2IP,PSMD7,FNDC11,ARF4,HUWE1,HAPSTR1,RAD23B,PSMB9,CLIC4,TENT5C,ACTB,PNMA1,BRCA1,MYO6,KRTAP4-1,SKP1,COIL,PSMC1,RGS19,NOP53,LZTFL1,PSMA3,TXNL1,SAT1,MYL6,PSMB7,ETF1,MAP1LC3A,ARHGAP25,PSMB4,PSMB5,NAB2,HAX1,PSMD10,DROSHA,WDR11,INO80E,PSMD3,RFC2,AHCYL1,PSMD12,MCM6,RPS27A,KCTD17,TRIM26,RBBP7,UBE3A,MRFAP1L1,PPP2R1A,ACTN4,PNMA5,ANP32A,B3GNT2 |
| 7.296e-10 | -21.04 | central_nervous_system | COSMIC cancer mutations | central_nervous_system | 16283 | 4739 | 16828 | 4835 |
MTHFD2L,IRF3,CD36,STXBP1,KLC2,PAX9,STOX2,PCMTD2,PRKAB1,UQCRH,DPEP1,IL18,DERL1,CSNK1A1L,SOX2,ST3GAL1,SLC32A1,PARP11,IFRD2,ZNF501,CEP97,POR,ST3GAL5,LCA5,STK24,NDUFB4,RAC2,TAS2R40,LRP6,MRPS21,PYROXD2,CDK4,NPR2,DPY30,NR1I2,CNNM4,ABHD4,PCDHB1,BRCA1,RBM7,TRAF2,KCNK13,ADPRH,PDHA1,BCL10,NOS1AP,KCNMA1,MBD5,STMN2,RGS2,DUSP19,NME1,KLK6,FKTN,DNAJC3,RNASEH1,TMED7,SERINC3,SLC41A3,STAU1,TSN,STOML3,EMP3,CHMP2A,OSTM1,VMP1,CBR4,SLC19A2,MSMP,HSPA8,GMPPB,CALHM2,ADO,CCDC25,TES,BECN1,LMNB1,EED,MRPS16,ABHD14B,ACSL4,MRFAP1L1,TGFB3,TRIM24,CIB2,ELP3,YAF2,MTRF1,ZNF592,EWSR1,B9D2,PROS1,GPX3,TMEM204,BLOC1S2,SNCG,SNAPC3,DDX39A,RAB40AL,AKAP12,IGBP1,SSU72,TRIM5,EIF4E,TMSB4X,COX4I2,CDKN2C,CALHM3,LHFPL4,NAT2,KHDC1,SPECC1L,BZW2,TSPAN5,OR10G9,RINT1,FABP7,ZBTB17,BCAP29,B3GALNT1,CREB3L4,EIF3K,CD274,FUT9,PHYH,HOXD12,RTKN,NTN4,RPLP0,IL10,UBE2V2,PREPL,THTPA,SH3GLB1,RNF113A,EFNB1,GOLGA7B,TSPO2,OLFML3,COMMD8,CSNK1A1,ITGA6,PELP1,IFNA10,DEFB114,MT1M,TFE3,GPHN,ISG20L2,HSP90AB1,POLE4,CSRNP1,ATG4A,SYP,ZNF862,MRPS23,FUNDC2,FCN2,RER1,SFRP4,RGS7BP,CDKN2AIP,DSTYK,ZBTB5,CCR2,ZC3H7A,AIF1L,TMEM123,CIDEB,ATAT1,ARMC7,IPO8,TMSB10,NKX3-1,F9,PGPEP1,GCNT3,OPRK1,MYO6,NDUFS8,CYP2C18,GPR137,APOO,SNX17,BCS1L,TMEM144,TOP1,NRSN2,TMX3,HTR5A,DNAJC22,EIF2B3,GBE1,CHGA,TCF23,PAPSS2,GPR65,TEX30,SEC61B,BCL7B,TOM1,TRIM54,CDC42SE2,ACBD7,FAM98A,RPLP2,GREM2,TGIF2,GPX6,POPDC2,OR4Q3,HTR1F,RDH10,LDOC1,PDCD4,GPAM,CREBBP,PRPF19,CXCL3,GTF2B,RUVBL1,SDF2L1,GIT2,OAS1,NKIRAS1,LAMB2,SLC13A5,CLDN4,RAB3D,ZNF287,KDM4B,TMEM184B,ACAT1,METTL14,VAMP5,GNG2,EDEM1,MBL2,MAP3K11,GTF2H2,JPH4,AMIGO1,PTS,TOR2A,RMI2,COL1A2,SLC35D1,SMU1,CSGALNACT1,R3HCC1,SAT1,TFCP2,ABHD6,CLDN1,METTL2A,FAM162A,CTDSP1,CCNB1,AKAP14,NDUFAF4,CRYBB2,ERH,ALKBH5,ADIPOQ,ANKRA2,UHMK1,LCP2,CRTAP,NPY5R,CXCR4,HSPA14,BRD9,HAND2,PGR,POLR3B,KCNH1,GTF2F2,DLG4,OR2H2,PAFAH1B2,CCL17,KIAA1191,CREB1,SERPINA5,BICD2,KIAA0408,RNF122,NAPG,GLIPR1,SQSTM1,RPP25,RBM12,RAN,TMEM177,FMO2,CXCL14,ADAMTS1,CLDN8,RPL6,SPRR1B,TUSC3,BNIP3L,DDX42,SLC7A14,GMPPA,CYB561D2,PXMP2,ATP1A2,PPP1R16A,MT2A,ZNF576,RABL3,UPF3B,ISCA2,GCA,TRAM2,PPP1CB,EHD1,MPV17,CHST1,FCHO2,RFXANK,PLAGL1,PAPOLB,SESN2,TRAM1L1,KLHL15,TAS2R5,TMEM203,PTRH2,FOXS1,CRYBB3,OR4F6,ACTR2,TMEM164,ACP6,SYNJ2BP,APLN,ZNF609,SELENOS,TMCC2,SLCO1A2,KCNK10,TMEM106C,SRP14,NUS1,MANSC1,GJB2,WDR3,PLEKHA8,KRT7,SUMO3,OPHN1,OGG1,ZNF687,CCR3,CMAS,RAB23,SFT2D2,PTGER1,RHOJ,CBLN4,WWP1,JUN,IFNG,TMEM50B,CD47,S100A8,HIRA,SPTBN1,TNRC6C,UTP23,GIMAP2,GNPNAT1,EIF3J,FERMT2,TOMM40L,RNASEL,CHI3L1,TNFSF18,PPDPF,DNAJC8,CRYGD,RAB33A,RNF167,FAM107A,FOS,DYRK2,EGLN3,CLDN22,OAT,MRPS28,RIOK2,OS9,RPL26,POMP,NFKB1,PRKAG1,HNRNPK,PAFAH1B3,LHFPL2,SCD5,MAFG,ACAP2,HNRNPA2B1,ATP6V1C1,GGCT,RCBTB1,PLA2G15,STX6,OR2A25,FANCG,MAPK1IP1L,CAPZA2,RB1CC1,SLC35E1,RFTN2,TPPP,CCL8,PPID,YPEL5,CMPK1,SNRPA,BEND5,WDR44,GPIHBP1,RAB2A,CTNNA1,CCNF,VAMP2,TRAPPC6B,CRBN,SACM1L,VPS33A,CD226,B4GALT3,ZFP1,PDYN,INPP4A,KCNIP3,FGFBP2,ARCN1,EZH2,RAB9B,AMT,DYRK1B,FN3KRP,WIF1,PHYHIP,STAT6,ACADSB,SNX24,ISG15,OR10G7,EIF4B,SMAD3,SLC25A4,MRTO4,PTHLH,PPP2R1A,PLEKHJ1,MLF2,ELMOD1,DERL2,TXNL1,TIMP1,IL6ST,TMEM59,RPL23A,LYNX1,RAB37,SLC6A11,FOLR1,CAV2,C1QL1,IFI35,PSRC1,FBXO25,CSTF2T,STK38,TIMM10,AP1AR,WEE2,PCDH19,PNP,RAB5C,STX18,ELSPBP1,ORAI3,SLITRK2,CDKN1A,GK2,RBFOX2,FOXN2,PPFIA3,OTUD7B,MED11,CLIC2,SDHAF2,AKIP1,SOS2,PIWIL2,PGM2L1,ROGDI,SLC23A2,GYS1,ACTL6B,FAM168A,SNIP1,SLC4A8,LY6G5C,UBE2D1,ZBTB45,ABHD13,HRH3,RAB1B,INHA,RPAP2,OR5L1,RGS5,RBMX2,NDE1,AMY2B,LDHAL6B,CCDC65,CD2BP2,TDRD7,HMBS,MRGPRX2,FLYWCH2,LRRC24,GRIA2,CAB39,KLK5,LIX1,DDX4,TMEM91,SLC43A2,ZCCHC9,TOP3B,TEX12,B3GNT2,HIGD2A,TAF5L,MYEF2,PNPLA8,UQCR11,NGB,GLT8D1,MOV10,GPX5,PCGF3,TCEAL7,GDE1,TMEM14A,CPSF2,CDH8,OR14J1,NUDT19,RANGRF,ABCC5,THOC1,FATE1,ATP2C1,DNAL4,RC3H2,UBXN10,PFDN6,LDHA,NUBP2,PCDHA5,SLC20A2,GSK3A,PRCC,RNF187,GPR162,APOBEC3C,ZMYND11,TXNRD3,ZNF513,SLC7A4,GJA10,EFHC1,SLC25A32,EEF2,THRAP3,XPO1,EXOC2,SURF4,INTS10,XPO5,RNF103,CREB3,TF,NEK7,UTS2R,MOB3C,LASP1,PHKG1,SPOCK1,FUT8,GTF2A1,WBP2,SH3GLB2,EIF2B5,GALE,CXXC5,OSR2,CIRBP,ANKIB1,ENDOD1,OR51S1,ZSCAN1,WDR37,EIF4EBP3,PSMD6,IL23A,DHX9,FURIN,SLC39A9,CREBL2,TXNIP,AQP4,GNMT,CCL25,GLE1,MSX2,RPRML,SNAI3,CDC37L1,PELI3,NLE1,KRR1,ISYNA1,APH1A,NDUFB8,EIF1AD,NAA11,FRA10AC1,PDIA3,XPOT,CXCL1,WNT7A,LEPR,STX17,LEAP2,HADHA,SOX21,RAB4A,TRA2B,DHX16,GXYLT1,OR6M1,NUDT16,LHFPL1,B4GALT6,KCNA2,HSPB1,CLDN14,ZKSCAN1,HSPE1,PGBD2,SIPA1L1,STAMBPL1,SERPINH1,RPL37A,OXNAD1,TMED1,RBM23,BRI3,ADAT1,OCEL1,HEXA,KIF1C,CHRNA7,GAS8,CDKL2,PAOX,BRMS1,CD3G,TBCE,SPATA2L,NQO1,IPP,NPVF,LMBR1L,AKR1C2,IGFBP4,OPA3,TAC1,LPXN,RASGRP2,ST13,DFFA,IL34,WWP2,RABAC1,ACAA2,UCKL1,RAP1A,CD2,POLR2I,TIGD7,FBXO30,PTCRA,TRMT6,FGF17,HBB,NEDD8,CXCR1,KCND2,NDUFA5,CCL21,SIRT7,IQSEC1,NOL4,FYTTD1,TAPBPL,ETV6,RRAGA,ABHD16B,RAP2B,TNFAIP3,MMACHC,TRAF7,MTMR12,DUOXA2,SV2B,HPCA,ZNF805,TCP11L1,SOST,EIF4EBP2,OR2A2,SIVA1,GFOD1,EMC4,GPR37L1,NDUFAF2,SNTA1,SNAPC1,SPRED1,H19,TSSC4,ALDH1L1,MAK16,NONO,POLL,USP39,CERK,SLPI,ZNF174,USP38,ZMAT5,RTP4,LSM6,SYNGR1,PROX1,PRKX,FGF13,VPS4A,NAB1,ENPEP,SFTPD,CLEC12B,CTNNB1,RAB8B,SOCS2,INTS12,CYP2D6,DCAF5,ESR2,CDK6,CWF19L1,SNRPD2,FAM13B,ADCY3,ANP32B,CPT2,CHST9,NDNF,AP1G2,DCAF8L2,RAB3C,MTAP,PWP2,URM1,CETN3,CTSK,CACYBP,S100A10,FAM200A,NFYA,DUSP1,TGFB1I1,BATF,TOLLIP,STX8,MRPL47,TMEM33,S100PBP,MPHOSPH10,AP3S2,KLF10,BMPR1A,FAF2,SCG2,ARHGAP21,RHCG,SPINK13,LCN6,SETD4,WFDC13,ACOT13,TMED3,RPGRIP1L,OR2W1,CCND1,FBXO9,COX7A1,POU1F1,CYC1,CCDC42,FCAR,NPTN,ENTPD4,ARMC8,SLC35A2,PTDSS1,ID1,DEGS1,CRYBA2,INPPL1,ING5,KIF2A,BACH1,MIA2,NFE2L1,AKR1A1,NOP58,SPATS2L,MRPS25,RBCK1,CTSD,PGAP2,MRGPRX4,FABP5,SPEF1,NUP107,OR52M1,SCAMP2,NLGN2,DEK,SLC5A6,PRKD3,CYP4F8,BPGM,CDKN3,PPIB,CD164,LYAR,EXOC8,PFDN5,UST,GNRHR2,TOM1L2,CNP,RND3,B9D1,NUDT3,TMEM156,GSTO1,PSMA3,CCDC69,GALNT1,SOCS5,AK2,EHBP1,MDM2,MGP,MRPL13,L1CAM,SNX20,WDR38,FIBIN,TLR9,COMTD1,FNDC8,DLX1,AKT1,APEH,FGD2,CRABP2,DPP10,PRRC2A,SF3B4,IL20RB,DKK3,RAB11A,PPIL4,CCNI,ASMT,CDO1,ZNF671,SLC25A31,SLC17A5,MEAF6,UGCG,RPS14,LIG3,LYPLA1,EDF1,ATP6V0B,TMEM219,ZNF207,POLR3H,TRIM3,C1QC,TMUB1,E2F6,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,GDI2,MRPL23,GFM2,RNF141,KLHDC8B,PLA2G5,KLK9,ARHGAP1,DOK4,CD99L2,SNRNP27,PRIM2,PDIA6,SDR42E1,UBR7,TRIM32,LTBR,CASK,GAL3ST1,OR4D11,GABARAP,FGFR1OP2,ELMO1,GRPEL1,TCP11L2,PRPSAP1,ARMCX1,UBE2A,CHRM4,CCT2,UBE2D3,ATP6V0E1,OR8B8,IRF1,ING1,STRBP,P2RY1,NHP2,NAIF1,TRIM23,TAAR1,SLAMF9,ZMYND19,CCR6,APOBEC3A,ZNF397,ID4,ZNF319,SEC14L1,XAGE5,CNIH4,GLUL,CDK5R1,NCKAP1,NRP1,ATPAF2,KIAA0232,CLU,LMO4,SWAP70,LRRC69,HSD11B1,CYP39A1,MYL12A,ITK,EIF4H,NCR3,FAM8A1,CHDH,GNRH2,SENP5,CYP11B1,PYDC2,GRM2,CTNNBL1,GALNT4,IDH3B,TLR3,GPAA1,JAKMIP1,ADGB,OSM,IL15RA,SLC38A9,RMND1,MIOS,PPP1R2,FAM78A,RAG1,ENY2,DHRS4,SLC35A1,IMMP2L,MEF2A,ZNF304,MRPL50,MRPL24,SLC30A5,KLK3,SNAPIN,TMEM215,FBXO42,ZNF24,TSEN54,SERPINB10,MTPN,WDR77,FZD4,MEST,ATP6V1G1,MFSD6L,LYG2,AAMP,MX2,GPBP1L1,ZCCHC10,SYN3,NDST1,DHRS3,TNFAIP8L2,DEFB116,SMAP2,CDCA3,RAB3B,KTI12,ABCB1,HBE1,INO80C,AZGP1,FGF1,AZIN1,PSME2,MLF1,GTF2E2,TBC1D10C,MAGOH,CCL19,NKX3-2,JAK1,LBH,SUPT7L,JOSD1,P4HA2,RS1,KIT,AFTPH,OR4D9,LSM3,GRSF1,RARRES2,KPNA1,PIWIL4,CSNK2A1,ATF4,GNG7,CTNNBIP1,GSTO2,KBTBD2,HEBP1,ALKBH4,SLC7A9,PACSIN3,SNAP91,MYH2,VRK1,ROPN1B,PGK1,DNAJC5,TMIGD1,CYP27A1,S100A6,DYNC1I2,LHX2,UBAP1,ZYX,CDC73,MMP9,BTF3,FGFR1,CAMK2N1,HCRT,SHC1,OR4K1,PYGM,CCDC127,FAM89B,RCVRN,PEX3,CRYGB,KCNJ11,PPP3CA,CD200R1,CIB3,TACR3,PRMT2,CAMK2G,BUD31,SRP54,TMX4,TTC4,SCFD1,CCDC47,CACNB4,RPL15,TUBG1,GHITM,ARMCX5,ZNF593,PRPF4,CD58,AGER,IMPACT,RAB18,FKBP14,IDH2,MCOLN1,PSMB5,CCT5,ENPP4,SLC39A7,SORD,SBK2,AGK,ANAPC2,FBXO32,SMCP,ACTA2,SIX5,TRIM21,ARMCX2,SPR,PPARG,GALNT12,ARFIP1,ZBTB38,TRIM37,HECW1,NFIL3,HNRNPC,SETD5,PTPN1,RMND5B,PGS1,RBBP7,SLC25A21,NIPA2,PAEP,RABL2B,CLDN11,FAM199X,TRAPPC1,RNASET2,SPTAN1,SLC35E3,NPY2R,LRP12,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,HEY2,PCDHB8,RBM17,AHCYL1,ALDH1A3,IZUMO4,ADM2,HNRNPH2,HMOX2,CLIC4,NPTX1,COX11,MAGED4B,TFPI,PAAF1,PRKCA,MMD,WRAP53,KLHL26,BET1L,UCHL3,TRAPPC4,EEF1A1,GAS2,TTC33,C2CD4C,OR2AT4,RPL39,TMEM108,SURF6,BRD3,FAR2,TESK1,DVL2,P2RY12,DNAJC30,FKBP1A,SRXN1,ZMAT2,NT5C2,DOLK,EHD3,ST3GAL4,MRPS18B,TPH2,PHACTR1,SAMHD1,CRYM,SPRYD4,KCNS1,API5,RPL9,TST,RNF5,DGCR8,ADIPOR2,LAP3,EFHD1,C2CD2,RCCD1,EXTL2,ALPL,SLC20A1,TRIM6,PYGB,SLC4A10,FOXP1,HOMER1,PDE8A,PSMB9,KCNJ8,SAMM50,ENC1,COX16,CUL3,OR5A2,PLSCR3,ARMCX3,CPLX1,POLR3GL,COX6A2,TMPO,UBTD1,MAD2L2,RBBP4,ABCB9,FAS,ATF1,GRB10,CSNK1E,SKA1,CHMP2B,ELOVL4,PAK6,DNAJC4,EIF3D,RBP5,AKT3,POLD4,MAN1A2,ERVFRD-1,CCDC92,TOMM40,GREM1,LRRC4B,COX4I1,FABP4,MPHOSPH6,ANAPC4,ARPP19,GDPD3,MRPL53,NLRP2,HDAC3,GLRA2,RPL29,BHLHE40,MAP1S,BPIFB4,PI16,CARHSP1,KLHL9,NPC1L1,TIMM8A,RAP1B,RAD21,AKAP17A,DNAJB4,TXNRD2,C2CD2L,ACTR1A,LAT2,FITM1,AIFM1,SNX14,POLR2G,COQ10B,FAH,CAMSAP2,ACVR1B,CTDSP2,RPL10A,SDC2,LAMP3,CNOT6,REEP6,MATR3,CHPF,S1PR4,TMEM11,TNFAIP1,FAM169A,AGTRAP,CRADD,PPP1R3C,KCNAB1,APBB3,MCMBP,SEMA5A,TLR10,WDR82,OR4S2,NAB2,FXYD6,ZBTB25,CD28,RNF11,CYTH2,SYNGR2,TAF7,APOC4,PPY,CRYAB,ROMO1,ZNF473,SELL,KIAA1143,GNL1,DNAJC2,GNB1L,ATP1B3,CCL27,ZC3H11A,SFRP1,WSCD1,ELF1,TMX2,HTR1A,METAP1,CYP2R1,GOSR2,SLCO1B3,FGF23,RANBP6,G6PC3,SLC25A39,PRR5L,CD14,ZNF704,FARSA,UBE2H,PTPMT1,EXD2,KBTBD6,CD86,PNMA5,MANBAL,OXCT1,ENO2,PSENEN,SLC2A8,BRIX1,IRGQ,CFL1,KLHL3,TP53I3,DPM2,RNASE6,RNF40,RPS26,KDELR2,DAP,DDX1,PSMG3,GPR173,OR5V1,TOP2B,SEC23A,TIRAP,RPS9,MYL6,GEMIN8,TUSC2,CASC3,SLC6A3,TCF21,CNKSR3,VAPB,PNMA1,CALML5,HEBP2,SP2,SMG8,TMEM50A,TAS2R39,LILRB4,MYC,FEM1A,CD40LG,SEC11A,CMTM6,VPS26A,EEF1E1,CCL28,MKLN1,SHISA2,KCTD10,RAB35,MAB21L1,PPP1R8,CDC42,SLC48A1,TNFAIP8L3,DUSP10,BACE1,SLC38A1,SLC25A26,SYK,ACO2,VPS16,CLN8,SNX1,FTH1,ALB,CCM2,PSEN2,SLC35F1,PIWIL3,IL2RG,PCSK9,PSMA6,KBTBD3,DNAJC24,AKAP1,CLEC1A,PARM1,LCN8,CPSF4,AGA,CD63,PCBD1,TTC23,AGR2,CACNB3,TMEM174,MORF4L1,NLGN1,TAX1BP1,AP2M1,PRDX6,KIN,PPM1M,TP53,INMT,NFKBIL1,CRELD1,PKIA,TRIM35,TRAFD1,PPM1B,GADD45B,SENP8,STX7,MGST2,OSGIN2,LIMS2,MZT2B,NECAP1,GPC4,HBA1,TSEN34,FTSJ3,SYNDIG1,GSTM3,IRF8,KPNA6,RWDD4,PTRHD1,TOX,FCER1G,CYB561,BET1,SLC25A46,HSD17B1,HEXIM2,TMED4,TBC1D17,TXN,MAF1,CYB5D2,RPS12,DAG1,ZBED3,DUSP6,MTHFS,SETD7,PPIF,SERTAD3,ZNF250,OR10A7,EIF1B,MT3,GABARAPL2,PML,PSMA4,DNASE1L1,RDH12,ZNF790,TAX1BP3,TNFSF12,CALY,GABPB1,ARF4,SCGB1C1,CLSTN3,TBC1D19,RASL11A,RGS6,CSTA,TFPT,ALOX5AP,ELOVL6,PRDX4,SLC25A14,NUP35,ZNHIT1,MECP2,CRYL1,SERPIND1,CHST7,ORAI2,RPL24,ENO1,OLFM2,GNPTG,PHF21A,TRMT61A,RHBDL3,CAMP,COX5A,SLC1A2,THNSL1,CELA3B,OMG,GPD2,CYP11B2,FBXL7,LBR,POP7,STY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1,PAQR8,PPP1CC,OR7D4,BAZ1B,PEX26,OR4E2,CYP7A1,SDS,DIRAS1,PRRT1,GINS4,ABCE1,ITM2A,DCK,ADH1A,EAF2,DCUN1D1,RPS24,MCM6,NUDT4,TRIM22,CYB5R4,SPOP,DEFB129,MRPL36,NR0B1,AMACR,FITM2,B2M,TIFA,TPRA1,SASH3,CASP4,SLC15A2,SLC52A3,LRAT,RETN,NKRF,MCPH1,ZDHHC8,ISOC1,EDDM3B,PSMB11,HSP90B1,TCOF1,RPS15,ASB1,FBXL3,QRSL1,VIPR1,ACTN4,GATAD1,PTGES3,RGS10,DUSP9,CFDP1,ATP2B4,SIGMAR1,IFNK,CXCL9,RBPJ,MRPL17,LRRTM1,RNF152,UQCRC2,MRPL33,KLHL28,EDEM3,TPPP2,EGLN2,RNASEK,BSCL2,CDK8,IQCF5,PHF23,COX10,CYB5A,TFG,ELOVL3,MTX2,MAEL,VLDLR,CRB3,DHRS7,CLVS2,VAMP3,WDR83,HTRA1,KIF3B,SPCS3,IKBKB,HELLS,MITF,LCA5L,RPL13A,TRIM8,FAHD1,HRAS,SYT4,WDR20,TAGLN2,RPP14,RPL8,IKZF2,CLEC9A,HADH,PGM1,NAT9,GABRG2,TFIP11,MEF2B,PRKCQ,WASF3,SMCHD1,ZSCAN5A,VSTM2A,B4GALT7,CLCA1,TMEM88,CNOT6L,MRPL40,GTF2IRD1,CD1E,TRMT11,ZDHHC15,MAP3K12,RSPH1,PPIA,FBP2,COX19,TMOD3,RPS4X,SOX3,LRTOMT,ALKBH2,RPS29,SKA3,DEFB121,CTSB,NCKIPSD,POGK,SLC16A4,TRIM52,ACOT8,HNRNPA1,LECT2,NFE2,CDC16,GNB1,GLTP,ORMDL1,ASB8,INPP5E,MED30,GHR,CXCL11,TREML1,MED9,SOCS4,CUL2,PYCARD,SLC6A8,FOXP3,LDLR,OR7E24,VPS4B,TMEM160,GSTA4,RHBDD3,RBM42,PPP5C,RASGEF1C,PCMTD1,CA10,MAD2L1,MAP2K6,SEPHS1,ANAPC11,LACRT,TOMM7,OVGP1,EMP2,LILRB1,TRIM46,GPX2,DNAJC1,HCLS1,GLRB,EHHADH,IL4,TIAM1,THAP2,TRIM63,PAQR9,STBD1,FAM110B,TUBB,LSM14B,COIL,ZFP64,FAM50B,SFTPA1,STX10,MCHR1,SFN,RING1,ZNF596,SF3A1,GNAI3,PSPC1,TRAPPC10,DISC1,CHID1,RBFOX3,AVPI1,SSR1,NETO2,SMARCD3,OSGEPL1,HP1BP3,PACRG,TLCD2,TAS2R16,GRM8,IL13,EIF4E2,MCM8,UTP15,CUTA,RMI1,DLAT,CAMK2N2,RIMS3,MT1A,CD38,PNMA2,ANKRD49,TAAR6,BLOC1S3,PHC1,PLXNC1,UGT2A3,GRAP,EPYC,SELENOT,MED17,DCP2,TMEM184C,NOB1,PHF12,ZBTB33,GEMIN7,BAG2,DCAKD,PLP1,XPNPEP1,RNF41,ZNF7,MGAT4B,CYP3A5,CD52,LMNA,PHF1,DCUN1D3,TIMM8B,IRAK1BP1,TMEM74,MSRB3,EIF3E,CTBP1,CDC42EP4,DDT,JUP,ALKBH3,EXT1,KLRD1,FASLG,CFL2,SLMAP,SNX5,OR4N5,ZMYM2,EXOSC4,BUB3,DNLZ,NR4A2,SLC25A45,NOSIP,SFXN1,UBAC2,KCNF1,UBXN6,NME2,CD4,ACO1,GANC,CACUL1,RALGAPA2,PPTC7,PCK2,G0S2,OR5I1,SATB1,TRA2A,BEND6,PRMT5,RAB31,STC1,OR8K1,DYRK1A,DRP2,SRGN,KLHL32,TSHR,SLC25A20,EIF2D,NEUROD6,AIG1,INSM2,C1GALT1C1,LGI3,EIF2AK2,GTPBP2,LIMD2,TRIM27,COPS2,NXPH3,SSBP3,DEFB115,CAMK1,WFDC5,SNX2,NOL7,TACO1,NSA2,TM4SF1,IRF2,PTTG1,ERP29,BCCIP,NOVA1,INPP5K,MCAT,NUDCD3,SEC63,SCN1B,CDC40,NELL2,NDUFB5,TM2D2,OR52W1,SUB1,CYP4F12,CPE,SLC39A13,DCAF4,ARHGEF6,PCSK2,CYB5R1,LRTM2,USP2,MYT1L,DTD1,REXO2,NTF4,POC1B,GPHA2,PCP2,TCTA,ADD2,SOD2,SCN2B,TEF,ANKRD10,NEU1,AMELX,VSTM4,GLO1,RAB1A,PDCD1LG2,MAP1B,ZDHHC17,FBXO31,VSTM2L,PIGK,PELI1,CNOT8,KLF12,MLN,WDR12,IAH1,KCNG3,CHST10,SOX9,APEX1,PRSS1,PSMC5,ITPRIPL2,GAB1,AKT2,HS3ST3A1,TICAM1,TLR5,LCN1,RFC4,PNPO,OR2D3,COTL1,GPM6A,PRELID1,ETFA,RIMKLB,AQP3,CD59,ECD,ACTR1B,STAP1,SMARCB1,HTR2A,ALG5,DEXI,SDHAF1,FMO1,STARD5,ABCC2,SUGP1,CLRN2,SRD5A3,DCAF16,MMP20,GTF3C4,DNM2,OR4K13,C1QL2,PLCXD3,REG1A,CA14,DIS3L,TACR1,ARHGAP19,CEP57L1,OSBPL8,CHRM5,NACC2,CEACAM5,NAP1L3,MTA3,DRD3,EMILIN3,RPF2,XBP1,TIMM13,TBC1D1,GPR34,GABBR1,ERCC3,THG1L,PDLIM4,MRGPRX1,HPCAL1,LIPT2,NAP1L5,SEMA7A,BCKDK,TRMT5,OR9I1,APOC2,CYB5B,ZCRB1,MED4,NPBWR1,PIK3CG,RPSA,ARHGAP15,RHOH,HYAL2,UBE2S,ERLIN2,RBM3,RRP7A,CCDC126,CORO1C,RACGAP1,MAGEA4,STT3A,ZNF343,STARD7,EGR1,DIO2,WBP11,ZNF436,SYPL1,CHTOP,TMEM126A,SETD3,GPR75,ACTL6A,ACP2,GNPAT,NDUFAF6,FOSL2,GFM1,SEC61G,EMX2,CENPM,SSH3,HOXB8,MET,FZD6,RETSAT,POPDC3,SLC7A11,ADIPOR1,PRM1,GAL3ST4,SERPINB9,MT1X,UBE2V1,TIMMDC1,SNX11,RPLP1,IMP4,TRNP1,HELT,PDE6A,DLG3,RHOU,TMEM176B,CEBPE,RPL22,CTLA4,RBM5,ATF3,RANBP1,DEFB1,IFRD1,ACSS2,MAP1LC3B,PRSS37,PDLIM3,TRAPPC3,CSRNP3,NRGN,LDB1,WNT2,GMDS,BIRC5,MFSD3,ANKH,VPS26B,YKT6,CAMKV,ESYT1,F2,ARL5B,EDC3,SAP30BP,HAPLN2,AANAT,UNC45A,FKBP2,PRSS35,TBCEL,GMNN,CYP26A1,NUDT1,RALB,TMEM87A,ISG20,TNFAIP8,PSMG2,DTL,SNN,SNRPA1,ARL6IP5,CEP70,ABHD2,ANKRD46,CTDSPL2,CCDC22,NDFIP1,KDM1A,HAS3,PRPS1,OLA1,MGST3,TSPAN3,BAD,NOC4L,UQCRC1,AKR1E2,CRHR1,PDCD10,GDAP1L1,SSBP2,LRRN4CL,ZSWIM7,WTAP,RPL31,CDR2,PTGER2,NETO1,NAA30,C9orf72,DOK6,SEMA3C,PSMB4,HERC3,DDX39B,CGRRF1,LSM4,IRF9,HSD17B8,TRAF1,RSL24D1,RASSF4,KCTD20,SERPINA3,CLK1,SKAP2,BRS3,ZMAT3,ZBTB6,PLEKHF1,AHSA1,KCTD16,SLC15A1,TRIM62,ZNF655,TEX19,GPR78,HNRNPAB,TMEM168,USE1,ST8SIA4,TMEM220,CD200,STRADB,LRP3,SIAH1,NCK1,SCG5,PHOSPHO2,OR6C4,NMRAL1,MAT2A,RFX5,TRAPPC2L,TMEM198,CMBL,COX7B2,CDKN1B,MEA1,TAF9,SCHIP1,HMGN4,SVIP,SMUG1,CDH7,ASCC1,TPD52L1,ZNF770,UBXN2B,DUSP18,FOXD3,FBLN5,LYRM2,MAEA,ZNF345,KIAA1958,EID2,CXCL10,CDC42SE1,COX7B,BGLAP,ASB11,RGS1,SDHC,NOL12,RHOG,FAM83A,SEC61A1,TTR,METTL18,RSBN1L,GAD2,HMGB1,PHF7,MRPS26,TUBA1B,CKB,THAP6,ZMYM6,EIF2B2,ARF1,GNG11,BTBD10,ZBTB26,LRRC14,PDCD5,PRDX3,EMILIN1,ZCCHC7,PHTF2,PPIL3,DPAGT1,CTSA,GPR83,LPCAT3,KCNIP2,SERTAD1,ZHX1,HNMT,ERRFI1,FA2H,ZC4H2,CETN2,TADA1,CBFB,ZC3H14,EFNA5,ASPM,SH3BP4,LEP,PITHD1,SMARCE1,RIT2,CACNG3,PDZK1IP1,PDE6D,OR5K1,OR4B1,LRFN3,S100B,TNIK,UBE3A,MRPL12,FGR,FAM20C,SPHK2,RCHY1,ZDHHC24,PPT1,B3GALT2,ARF6,DCTN4,MAP2K3,SEC22A,DOK5,FIG4,LSM12,CXXC1,RPL7A,SLC41A1,LAMTOR2,PNRC1,MED29,UBE2I,UCP2,TMEM106B,MFAP1,MXD1,MAP3K3,KRTAP4-1,ARL11,FHIT,EZH1,ARGLU1,TECR,MRPL16,RNF7,SLC6A7,MAGEB1,DICER1,RPL19,IL21,SLITRK5,SAP30,DDIT4L,RNASE4,POU5F1,MSN,HBM,FGF16,ZNF362,GLIPR2,MID1IP1,TDP1,SPCS1,PLEKHF2,SNRNP70,SERINC1,HINT1,PYCR1,THOC6,TNPO2,CCL11,RPAP3,RAB9A,RXFP2,MARCKSL1,IFNAR1,SDR16C5,SLA2,TBC1D16,SLC7A1,CA12,SPATA4,CMTM7,ADRB3,FMOD,CCND3,ARL6,RAB11B,STX5,LEMD3,IRF4,CSRP1,LYPLAL1,HSDL2,OPRL1,PLP2,ABCF1,DUS4L,NUP62,RNF139,SMG5,DYNLL1,SLITRK1,DDIT3,SRP72,RPL28,HCFC1R1,CACNB2,EDEM2,FIS1,MVD,STK38L,PIGC,ARFGAP1,CYP4F22,PREP,SHC3,CDC26,CCL24,SNRPD1,JUNB,ALCAM,RNF182,TIMM17A,SMAD9,RELL1,UFSP1,PTPN5,LIPA,TCEA1,BCAS4,HM13,SLC39A10,MCCD1,LCN15,MB21D2,PGAP3,OAZ3,VCPIP1,PCYT1B,CSF2,KRT8,PRELP,GJB1,GCHFR,CHCHD2,SKP1,ZNF200,IZUMO2,TPST1,HNRNPH3,LCP1,AGGF1,ATG16L1,SIGLEC5,HDAC11,DIRAS3,TP53TG5,TTLL10,RPL4,SEC14L5,RGL1,SUV39H1,CKS1B,DYNLRB2,HBP1,SLC25A3,RWDD1,RBM41,COPE,LSM5,DCTN3,IRF2BPL,PRKCB,PABPC5,HCFC2,BMPR1B,OR4M1,SPDYE4,TULP3,HS3ST1,BARX2,PSMD1,MPP1,ADH1B,SRM,MED27,RANBP10,BLVRA,CRYZ,FOXC2,PITPNA,RAB32,CRYBA4,MLH3,PCBP4,APOBEC3B,ATP6V1D,CDKN2D,ESD,GPR37,VWF,PSMB10,CDK17,TMEM39A,ART5,MYLIP,SUPT4H1,FAM174A,VPS39,PTPRZ1,IFI16,SART3,CLP1,CLPX,OR5AN1,CFTR,INA,ATG3,ZNF263,TPPP3,SNX10,CA2,SGTA,MTDH,USP6NL,GSTCD,E4F1,TMED9,DLST,GTF2F1,SSX2IP,SYNPR,BCL6,LYPD6,ELMO2,TRPC1,ASPA,BCL9,DR1,CBX3,HS2ST1,GTPBP8,MIS12,HSD17B10,CAND1,PRNP,GABRA1,TMEM89,LST1,PICALM,COX6C,XAF1,PIK3AP1,RPIA,VTA1,FEM1C,COCH,NUDT2,PSD2,BAX,PEBP4,GH1,ATP1A3,GSTM4,CRTC2,NPM3,TSPAN15,TMEM38B,SNRNP40,FAM83B,PIK3CA,IVNS1ABP,CDH11,PSMC3,JAKMIP2,TMEM185A,PAIP2,NDUFS2,MAD2L1BP,TMEM47,LY96,AP1S2,APEX2,ADORA3,SF3B1,TAB1,AKR1B1,CNN3,CPT1B,RBM27,ZBTB39,ANKMY2,PHF13,RPL26L1,CGGBP1,CARTPT,SESTD1,KLHL1,FOXA3,PARP2,NF2,ABHD12,BANF1,TNF,GGH,NUDT9,CYGB,IL17F,PPAT,SNRPB2,LZTFL1,TFB1M,SUMO2,CCR4,CHRAC1,KLF3,MT1E,CRISP1,ELK3,LRRC40,DPH3,CD81,UBE2E2,RHOBTB3,HGS,POLR2L,POLDIP3,FSTL1,DBR1,TAS2R13,COX6B2,TMEM170A,RNF133,PRKCE,ZNF451,WDSUB1,GNRH1,PRKRA,TSPAN17,WDR5B,ZDHHC4,CDC20,TIMP4,XRCC5,ACCS,SNRPG,AIPL1,PEX13,TBC1D25,TYROBP,WDR11,NHEJ1,SLC35B3,FHOD3,IL2,SEC13,VMAC,NBN,TNFAIP8L1,MPPED2,PRL,CDC7,OLR1,SLC19A3,FBXO8,NDST3,RBBP8,MGAT4A,SGMS1,IGSF11,CYP2C9,MRPS34,TRIM45,ATAD1,DUSP21,CAV1,B4GALT4,YIPF3,LXN,TCEAL8,RPS2,ITGB5,RGL2,NDUFC2,TMEM205,TRIM34,ICOS,NINJ1,BLCAP,AKR1C1,CSNK1G3,RAB39B,MRPS11,HUWE1,ABHD10,CPLX2,PRND,SREK1IP1,FTSJ1,CNTROB,CCIN,UBE2L3,TTPAL,PMAIP1,EIF3G,MEPCE,SPEM1,CYP3A43,PDE4B,PAQR3,CREBZF,NT5DC1,MRPS18C,TRIM36,JAK2,PROK1,HSPB2,COMMD9,STK3,CBLN1,LILRA2,TNKS2,LY6H,DCAF12L2,PLSCR1,PTP4A3,ZBED1,RB1,TRIM29,CORO6,OIP5,DPH5,PNMA3,MCL1,FAM53C,GSTA2,TMEM127,HCAR1,NDUFA1,DDAH1,GPR35,HFE,ALG11,PLG,DMTF1,CDK12,DLK2,PSMB7,TNFAIP6,FBXW7,CTU1,EPHA4,GXYLT2,KCNJ2,CITED1,TXNDC17,LIAS,ARL4D,NPY1R,GCLC,PSMD10,CPLX3,TNNI3K,GPR17,GPC1,PLCB1,PRSS23,ZNHIT6,ARL2BP,ING2,SPP1,FRZB,FAM149B1,CHRM3,TSR2,GJA1,MAGED2,SLC29A1,SURF2,RNF222,REEP4,AASDHPPT,CCNA2,TM4SF20,OR8H3,SLC8A1,LSM14A,CAPN2,YWHAZ,STARD3NL,ICAM2,ABHD8,TNR,OR6X1,TM4SF18,BOK,CEND1,ZNF511,EHD4,FAM81A,SLC25A1,STAMBP,HNRNPF,HOMER3,MAGEB10,CXCR3,OR4K2,GRM1,PCGF6,TAF1D,KCNJ10,SHPRH,ADORA1,SLCO3A1,SPATA2,FBXW4,P2RY4,ST3GAL2,TAS2R7,CD209,IP6K1,IL2RB,PTGFR,SPINK9,SLC25A24,GLCE,SSNA1,GK5,RPL10,TRIP4,STAR,SUPT5H,PDCL,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,POLR1D,GPR160,DTWD2,PSMD3,RNF10,POLE3,KRTAP8-1,GP9,OR51E2,ZDHHC16,TEX261,OR4D5,PPP1R11,MDFI,MSH6,RAP2A,CD40,AIP,SLC6A2,TNFSF15,CRY1,ARFGEF1,MED22,NOG,PMPCA,TLR8,PDE2A,ZNF428,CDIPT,TNFSF8,PYCR2,PLAC1,PSMD7,SCAND1,SIN3A,CDK7,RAB6A,CTTNBP2,RGN,FKBPL,DCTPP1,TMEM100,OR4A47,CPXM1,THAP1,UNC79,CD34,FBXL4,PRCP,EID2B,CCDC90B,RGP1,TRAF3IP3,PIWIL1,TAB2,SRPK2,RNASE9,GADD45G,LDB2,YPEL4,PRSS8,TMEM107,RPA2,TMEM81,SAP18,EXOC3,CAP2,SPG21,TIA1,SLC22A6,DDR1,RNASEH2C,HSPD1,EIF1AX,TMEM115,NPC2,PNPLA4,PIAS1,LRRC28,TCEA2,PARD6A,DPEP3,TMEM183A,BTG3,RUSC2,CD9,OR1M1,IGFBP3,GADD45A,GRPR,VPS54,SLC25A27,TGFB2,RBMS2,ATG9A,ZNF622,S100A11,THOC3,BOLL,MX1,PIGA,GLOD4,TRIM44,NR1I3,LRP10,PAIP2B,VAV2,CCDC3,ITGB8,BTG2,TMEM229B,GNB3,HINFP,NUFIP2,CMC1,THAP8,WDR45,CRYBA1,MPV17L2,NRM,GNA11,SERTAD2,HSPA5,HSPB6,TICAM2,FAM20B,FHL3,PPWD1,PQBP1,GPRASP2,KLHL25,TMEM165,OR8B4,RPE,SULT1B1,FAM3C,PTP4A2,MFAP3L,SLU7,VEZT,IRF7,SLC25A5,PRR13,WSB1,LYZ,TOPORS,OAZ1,FAM151B,CYBRD1,ZNF518B,ADCK1,MACROD1,FAM136A,SLC35E4,MECR,SGIP1,MRPS17,FEM1B,UBE2G2,MRPL9,FXN,SUPT3H,UPRT,KLRC2,TOX4,IFT172,TMBIM1,CYTH4,CPNE2,RAMP3,IER3,TRIM26,NUCKS1,CENPL,RRAGB,SNRPE,DLGAP4,CMA1,GRIK1,IL18BP,RASL12,ANXA4,GALNT2,THUMPD1,GORASP2,TTC9C,PELO,GMPS,CCR7,IGF1,RXRG,SNAP25,DMPK,ELFN1,MBD3,CDC23,TANK,BRAP,SYNGR3,MPG,RDH11,KCTD3,PIH1D1,LRRC8A,GNGT2,SSPN,CNPY1,HAUS2,OR5M9,ELFN2,GALC,RP9,NKAP,LBX1,PFKFB2,ARHGAP12,EIF5B,SRFBP1,DIRAS2,ACER3,MREG,YTHDF2,FAM161A,ANKRD6,PDE12,EDA2R,LCORL,LMO2,FKBP1B,PSEN1,MAGEC2,OR13A1,SSBP4,RASSF8,CLEC6A,KCTD17,RBP2,TLCD1,AQP11,ZNF581,SUCLG2,PDE7A,DUSP3,CIAO1,ATP8A1,KIF3C,VPS18,GHRL,NAA16,SLC12A2,RPS20,RUNX1,GJC1,SCML1,TAPT1,MED10,TYMS,ZFAND6,RPS10,SPRY1,CCDC106,ETNK2,CLDND1,TBCCD1,TRAF6,ROCK2,FUBP3,KCND3,VPS72,KRIT1,GIN1,TKTL1,RPL18,MGMT,MDC1,TRAPPC6A,SP1,MTCH2,ITM2B,IMPA2,TRAM1,TADA3,FUNDC1,AP1M1,ECHDC1,UBA52,TMEM196 |
| 7.401e-10 | -21.02 | negative regulation of apoptotic signaling pathway | biological process | GO:2001234 | 244 | 117 | 18204 | 5365 |
GNAI2,ACVR1,MIR222,CTNNA1,MIR17,CSNK2A1,XBP1,AATF,PPIF,SLC35F6,RRN3,AR,MIR221,SNAI2,CAAP1,NRP1,KDM1A,BCL2L1,PSMD10,SLC25A5,PARL,STRADB,CTTN,RB1,PIH1D1,TERT,SYVN1,SIAH2,IL1B,TMBIM6,TXNDC12,CXCL12,AKT1,GCLC,ZMYND11,CLU,LMNA,CCAR2,SELENOS,SLC25A31,CREB3,NOG,BOK,IL10,RAF1,CX3CL1,IL1A,VDAC2,TNF,IGF1,GPX1,CX3CR1,GSTP1,BAK1,TAF9,SLC25A4,FGF10,TRIM32,CTNNB1,TNFAIP3,MCL1,BRCA1,HTRA2,HELLS,PSEN1,MIR21,FXN,IVNS1ABP,PRELID1,NFE2L2,EPO,FBXO7,LGALS3,NR4A2,NDUFS3,ING2,IL7,TPT1,PYCR1,CDKN2D,MIR210,MIR195,PELI3,SRC,SCG2,PTPN1,ENO1,MIR132,PCGF2,MIF,PRDX2,RB1CC1,FAIM,ITGAV,ACKR3,PAK5,EYA3,IFI6,GHITM,ATF4,TMBIM1,RNF34,NONO,TMEM14A,CSF2,ICAM1,PEA15,MDM2,MIR142,HSPB1,SOD2,ACAA2,MMP9,PPIA,IER3,BAX,ITGA6 |
| 7.444e-10 | -21.02 | DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit) | protein interactions | 1650 | 361 | 155 | 19454 | 5460 |
HEXIM1,RPA2,JUP,PICALM,GRM2,SSR1,HSP90B1,METTL14,FGFR1,GABRA1,CDC42,CFTR,DAD1,PIAS1,HSPA5,SYVN1,RNF113A,DERL1,RPA3,ATP1A1,NRP1,UBE2H,CALU,DNAJC10,TIA1,HMOX2,TUFM,RAB2A,GSTK1,TECR,UQCRQ,VIRMA,SEC63,CTSB,PLAGL1,SEC61A1,PTEN,CCNF,UQCRC2,ILF2,FURIN,SBK2,RNF8,HSPA13,DDX39A,CCDC47,TNRC6C,TUSC3,PSEN1,FKBP8,NSG1,HUWE1,TMEM33,SRPRB,BACH1,DNAJC30,EMC2,IGF1R,FAF1,RAB1A,EHD4,RAB3A,POR,SLC2A1,ESYT1,HDAC6,MOV10,DPP4,ATP5MG,EMC4,EDEM1,FAM20C,CDK9,TMPO,ZBTB2,ASB11,TMED9,FZR1,SPPL3,MYBL2,SEC23A,RAC2,COQ8A,STT3A,HACD3,COX4I1,SLC25A3,VAPB,PPT1,RND2,RFXANK,EDEM3,TOMM22,PGRMC1,SAP18,EMC1,UFL1,STAU1,SSR3,HDAC5,PMAIP1,EP300,RNF10,DDX39B,DNAJC3,DUSP9,JAGN1,TMEM106B,EXD2,NTRK3,HSP90AA1,ILK,RIT1,ZMPSTE24,ARHGAP19,SPCS3,TOMM40,MYC,OST4,CUL3,ESR2,LGALS3,SEC61B,VDAC2,LMBR1L,CYB5R3,MOB3C,EZH2,RPN1,PDHA1,DNAJC25,SOX2,ISG15,RAF1,B3GNT2,E2F4,PAEP,KRAS,EMC8,VDAC1,ATP5F1D,RB1CC1,AGR2,FAM241A,DDRGK1,RAB5C,HSP90AB1,DNAJB9,RHOH,IGBP1,NXT1,EED,ATP6V1A,CYB5A,PHB1 |
| 7.502e-10 | -21.01 | REEP4 (receptor accessory protein 4) | protein interactions | 80346 | 190 | 93 | 19454 | 5460 |
FBXO7,FMO1,PHAX,SFXN2,RTP4,SLC7A8,SEC63,COPE,PLP2,ST7,ATG16L1,SEC22B,ACACA,LEMD3,RPA2,TMEM254,RTN4,DERL1,TMX2,RPA3,ORMDL1,LPAR1,TMEM167B,TMEM199,TMEM19,SLC25A46,TMEM42,ESYT1,HSD17B11,COMT,FUNDC2,CAV1,SPPL3,DNAJC1,VTI1B,UBIAD1,YIPF4,SELENOK,TMEM31,UNC50,ERG28,YIF1A,SFT2D2,RIGI,TMEM50A,DNAJC30,CAV3,SFN,YWHAZ,EDNRA,RETREG3,TMEM229B,SEC61B,CYB5R3,APEX1,REEP3,B4GALT3,TVP23B,TAX1BP1,SEC62,OTULINL,VAMP1,BET1,CAV2,VAPB,CD40,TSPAN15,PXMP2,YWHAG,YWHAH,SYNJ2BP,PTPN5,TMEM208,PMP22,C2CD2L,YWHAB,BCL2L1,FAM241B,SELENOM,STX5,KCNA2,CD63,YIPF3,DNAJC25,TMEM14B,CYB5B,RPN1,STIM1,EZH2,CTSA,TMT1A,LEPROTL1,TMEM60 |
| 7.759e-10 | -20.98 | ATG3 (autophagy related 3) | protein interactions | 64422 | 274 | 124 | 19454 | 5460 |
GNAQ,RPS23,RPS11,RBPJ,GDI2,VPS33A,MAK16,GABARAPL1,ARFGEF1,NAA15,BUD23,RPS4X,EMC8,SRSF7,RPS24,RPL31,RPL23,RB1CC1,MED4,VPS4A,XPO1,ATG7,MAP1S,TAF7,ATG9A,SPTAN1,NOP58,MCOLN1,WDR82,MAP1LC3A,POLR2L,RPL9,RPL8,TRMT112,VPS18,ETF1,ACTL6A,NRBF2,SAP18,RPP14,IL1B,EP300,XRCC5,VMP1,POLR1B,RCL1,TNFAIP8,BAG3,LDB1,KANSL3,ATG101,NOP16,RAB11A,CUL3,CREBBP,RPL19,ACTB,TAX1BP1,MED17,PSMD4,RPS9,RAN,FAU,TAF2,FCF1,AZI2,MAP1LC3B,ZNHIT1,TBK1,SEPHS1,VPS16,PDE2A,IMP4,NOC4L,HUWE1,PAK1IP1,CCNY,RPL23A,MAP1B,RAB1A,EIF1AD,CLP1,BECN1,TRAPPC2L,GAPDH,EDEM1,ERCC3,EI24,NCBP2,DKC1,RPL35A,PWP2,HRAS,GTF2B,DFFA,PTPN1,UTP15,TFIP11,GABARAPL2,PPP1R8,ATG16L1,RPS14,MYLIP,CLU,GABARAP,AATF,NHP2,RPS15,WDR3,NLE1,BAP1,RPL26,RPS17,SUB1,RPL7A,VPS39,RPF2,ADRM1,PITPNB,MOB4,WDR45,POP7,PELP1,CCNF |
| 7.759e-10 | -20.98 | PANX1 (pannexin 1) | protein interactions | 24145 | 274 | 124 | 19454 | 5460 |
FAM83B,RPS9,TMEM229B,ARF1,ATP6AP2,BAG3,VEZT,RAB11A,SCFD1,FAXDC2,VMP1,LAMTOR1,LMNB1,RHOB,PEBP1,UFL1,GRPR,OTULINL,YIPF5,TOMM22,RPL27A,NOTCH2,PGRMC1,TOR1AIP2,FDFT1,VAPB,UBAC2,CYB5A,STX5,RAB35,TMEM97,CX3CL1,RHOH,BUD31,PPFIBP1,DDRGK1,SLC38A7,RPL6,CDK5RAP3,RHOG,EFNB1,RINT1,RPS4X,PSMD12,RPL28,TNF,KRAS,EMC8,FAF2,CYB5R1,KIF2A,TOP3B,STBD1,MACO1,RPS11,STIM1,CDIPT,VAMP3,VIRMA,SEC63,RHOJ,SLC25A4,DEPDC1B,FBXO7,HMOX2,GORASP2,VAMP5,RPL7A,EPHA2,ATP1A1,TYROBP,ARFGAP3,VIPR1,DERL1,TEX264,TMEM209,YKT6,NF2,RPL4,HCST,CDC42,RABL3,UBA52,ARHGAP1,SEC22B,CHRNB2,LEMD3,SSR1,USE1,SLC12A2,CDCA3,RAC2,PTPN1,SRPRA,HRAS,CAMLG,LMAN1,CAV1,DNAJC1,HM13,ATP1B1,TMEM199,DHRS7,AQP2,OSBPL8,TUBG1,ESYT1,RPL3,STX18,SNAP23,PALM2AKAP2,NSDHL,SLC6A8,CTNND1,FKBP8,RDH11,TMEM33,SRPRB,LBR,UBIAD1,RPL15,SNAP29,PREB,CCDC47 |
| 7.794e-10 | -20.97 | PSME1 (proteasome activator subunit 1) | protein interactions | 5720 | 252 | 116 | 19454 | 5460 |
TUBB4B,PPP2R1A,CSNK1E,PFDN1,PSMD12,RNF26,SAR1B,TRIM26,PSMA2,PSMA1,RUVBL1,MRFAP1L1,CCT8,PABPC1,CBL,RPL23,PSMD10,AGR2,FIG4,XPO1,PSMD3,PDIA3,WWP2,CACYBP,CCT7,TCP1,PSME2,PSMB4,PSMB5,EIF4B,PSRC1,PIH1D1,PSMB7,PAK2,PPP1CB,PRDX3,PSMB3,RPP14,PSMC1,FBXO30,FXR2,OXCT1,HSPA8,NUBP2,DDX5,PSMA3,EMG1,CYP1A1,PSMD14,PSMD1,BAG3,MYC,PIK3R3,CUL2,PSMA4,PSMB6,USP5,APEX1,PSMD4,TENT5C,ACTB,PSMD6,SNRPD2,POLR3B,POLR2F,PSMC3,GPX7,MAP1LC3B,PSMB9,PSMB10,SMN1,CAPZA1,SEM1,PSMA5,HUWE1,CSE1L,HNRNPK,RAB1A,PSME1,GLUL,DNAJC7,TSNAX,TUBG1,PSMG2,PSMD7,ATP1B1,KARS1,EMC4,PREP,PSMB1,AIFM1,SCLT1,RPA2,LMNA,ELP3,PSMC4,ARHGAP1,HSPA5,GTF2I,INPPL1,BAP1,UBE2H,PSMG3,BICD2,FBXO7,PPP1CC,PSMB2,SEC13,PTPN11,IDE,VIRMA,ADRM1,GANAB,PSMC5,SENP5,PSMA6 |
| 7.830e-10 | -20.97 | GDI2 (GDP dissociation inhibitor 2) | protein interactions | 2665 | 164 | 83 | 19454 | 5460 |
ISG15,SOX2,CMPK1,CHMP4C,RAB6B,RAB4A,SKA3,EZH2,VPS33A,TAGLN3,EMC2,RAB13,DNAJB4,HNRNPA2B1,MAP1B,RAB1A,RAB18,SAR1B,RAB8B,HUWE1,RAB23,ATG7,RAB22A,FAM20C,RAB5C,RAB32,RAB3A,HSPB1,HAX1,AGR2,PREP,MGME1,AIP,RAB35,RAB31,CD274,RAB11B,TOMM70,RAB33A,RAB1B,FZR1,CPNE1,GLRA2,RAB6A,CFTR,NEK7,UBE2M,PPT1,QRSL1,LMNA,RPA2,RAB9A,AKAP1,PMAIP1,RAB5A,HSPA8,SIRT7,PEBP1,BAP1,RPA3,EMC1,UFL1,DNAJC8,BAG3,RAB11A,CUL3,RAB2A,UBE2H,ATP1A1,ATG3,BICD2,MACROH2A1,SGTA,CCNF,PAPSS2,SMURF1,NREP,ACTB,TUBB,PRKCE,EIF4H,RAB14,NDN |
| 7.961e-10 | -20.95 | CHD4 (chromodomain helicase DNA binding protein 4) | protein interactions | 1108 | 895 | 333 | 19454 | 5460 |
NACC2,CTBP1,NUFIP2,NCOA5,MTF1,RPL27A,TRA2B,HNRNPA0,FXR2,STAU1,PHB2,SAP18,ZBTB5,DDX39B,SLU7,XRCC5,SF3B1,HSPA8,EP300,LCN1,DDX5,FTSJ3,H2AZ2,CHTOP,H1-10,H1-1,PRSS1,MYC,HNRNPAB,HNRNPC,BTF3,CPSF2,MATR3,ATP5F1B,LRIF1,CBX5,RPL10,APEX1,VDAC2,ZMYM2,MCPH1,TUBB4B,STMN2,PDHA1,MTA2,SMARCB1,RPL18,MOB3C,SUPT5H,SOX2,TUBA1A,RPS7,NAB1,HNRNPF,KRAS,VDAC1,RUVBL1,RPS4X,CCAR1,HNRNPDL,POLDIP3,RPL31,PABPC1,TOP2B,ABCF1,RUVBL2,EWSR1,AGR2,DDX1,IFI16,BAZ1B,DDX50,RPL6,NOL4,CTNNB1,EIF2S1,RPS10,HNRNPL,SUMO2,SNRPD3,SNRPA1,LYAR,SIN3A,FABP5,RBM5,SRSF1,S100A8,EED,RPA2,ZNF326,HEXIM1,TFIP11,HECTD1,LUC7L3,SNRNP27,WDR3,RPS15,KDM1A,HSPA5,RPL27,DDX46,BAP1,PML,BANF1,RNF113A,LACRT,IGF2BP1,UBE2H,SMARCA5,RPL7A,SUB1,RPS17,FBXO44,H2BC9,PRKACB,OGG1,NMI,SRC,CXCR3,SF3B6,RPS3,LIG3,CSNK2B,MACROH2A1,DDX42,CHAMP1,CBX3,IK,RBM34,CAPN2,RNF8,STRBP,RPSA,TP53,ACTR1A,H2AX,ZNF581,WBP11,ZMYM3,ZMYM4,H3C1,KPNA2,HNRNPK,PHF1,RPL17,SNIP1,RPL3,DHX9,SNRNP70,RPL24,H2AC4,KPNA1,AKAP8L,RPS2,RPL10A,USP15,RBM17,CSNK2A1,API5,GAPDH,RPS16,BRMS1L,MIF,SHPRH,DKC1,TMPO,CDC5L,SYNCRIP,ARL4D,ATP5PO,USP39,ADNP,TCF19,MFAP1,SLC25A3,MYL6,ACTL6A,WDR77,PPP1CB,COIL,AZGP1,LMNB1,RPS5,RIT1,DSN1,CUL3,IKZF2,PROX1,SMARCE1,RIOK2,PRPF31,MCM4,MCM3,RBM15B,RPL35,DYNLL1,TUBB,RBBP4,ACTB,MAD2L1,RPL19,ERH,TNPO3,SNRPD2,RPS9,EZH2,RPN1,RPS11,RBPJ,RAF1,LGR4,SAP30,RBBP7,ZNF592,G3BP1,RPS27A,MCM6,SSRP1,GSTT1,PCGF6,RAD21,MORC2,HSPD1,SLC25A5,HNRNPA2B1,PPAN,RPS24,BAG2,SRSF7,DDX23,NAB2,HNRNPD,LYZ,RPL23,HMGA1,PRPF19,INSYN1,HNRNPA1,EIF3D,NOP58,SPTAN1,CCAR2,RPL7,DHX15,RPL8,RPL9,PHB1,HP1BP3,RPLP1,RPLP2,JUP,DCTN4,SNAI2,RPLP0,HNRNPH3,MACROH2A2,SF3A1,RPS14,TPT1,GTF2I,RPL4,FBXW7,SMC4,MBD3,CXXC1,BRIX1,RPA3,HELLS,ZKSCAN1,PRPF4,SIRT7,PNO1,MIS12,DPEP3,MTDH,H2BC12,STK24,CDC73,LCORL,ZNF687,ATP5F1A,RPL26,PPP1CC,AR,KPNA6,NONO,NDN,ZNF622,TXN,VIRMA,RPL22,DEK,CCNF,ENO1,EIF4A3,TUBA1B,GANAB,TRIM27,ALB,UBE2I,RPS20,PTEN,UBASH3B,RPS12,ILF2,MTA3,DDX39A,EEF1A1,CD2BP2,RPL15,CDK2AP2,NOC4L,THRAP3,RPS13,MDC1,RIGI,MSH6,PPP1R12A,NKRF,TCOF1,RPL23A,BRD3,RNF14,SUV39H1,TOP1,THOC1,ZBTB2,RPL12,H2AZ1,RCHY1,KRR1,MYBL2,PWP2 |
| 7.991e-10 | -20.95 | organonitrogen compound catabolic process | biological process | GO:1901565 | 1115 | 420 | 18204 | 5365 |
RNF7,ERLIN1,CMA1,BLVRA,ANAPC15,KCTD17,NEU1,LYPLAL1,SMPD2,MOXD1,DCTPP1,RC3H2,APOBEC3F,UBE2I,IDE,TRIM26,PSEN1,MTM1,NUDT1,HTRA2,KLHL3,SPOP,ZMPSTE24,CYP2D6,PSMB10,HSPA5,WWP1,ABHD12,FBXO11,RCHY1,SAT1,ZER1,ANAPC4,IER3,ALDH1L1,FZR1,ABHD10,FAF2,CDC20,AUH,APOBEC3G,FITM2,NUDT18,CDC16,WWP2,PDE7A,HSP90AA1,ACADSB,RNF34,UBE2A,FBXO8,APOBEC3D,HTR2A,OAT,HERC3,SLC6A7,STPG4,HGS,RNF126,PGPEP1,EDEM1,USP14,ANAPC11,CTSB,DNPH1,PRPF19,OS9,GAD2,TOPORS,TST,PSMB1,DNAJB9,UBXN10,BAG3,NDFIP1,CBL,PAOX,RNF11,FBXL4,OTUD7B,DPEP1,TMUB2,PDE1A,DCAF11,UCHL3,SLC6A3,RLIM,NEDD8,ZFAND2A,KLHL15,VPS4B,RNF8,ISG15,FAM8A1,RNF167,SULT1A3,LDHA,PDE8A,GDPD3,FMO1,PGAM1,SDF2L1,FEM1B,PLA2G15,EDEM3,PSMB9,FAF1,FBXO22,AASDHPPT,PCYOX1L,HEXB,CLN8,RNF139,CUL2,GNPDA2,UBE2H,HINT1,GAPDH,RBCK1,SIAH1,LIPA,CHMP4C,CSNK1A1,LYG2,NUDT7,APOBEC3H,SGTA,NQO1,RNF20,GNPDA1,UFD1,KLHL22,HECTD1,COP1,PDE9A,CDO1,RNF187,CHMP5,FBXL14,VPS4A,ANAPC16,UBE2D3,CDC26,MDM2,PSMB5,IDO1,CTSC,ENC1,CRBN,HUWE1,ENO2,HMOX2,FBXL7,DDIT3,TRIP4,UGT1A1,COMT,CHMP1B,HSPA8,FBXW11,GGT7,TNFAIP1,NUDT3,OGG1,MPST,HSP90B1,DCTD,APOBEC3B,AMT,EDEM2,CTSD,PSMD14,FBXO3,RNF133,MTHFS,RNF144B,RAD23B,TRAF2,FBXO31,DBH,PSMA2,ERLEC1,TMEM106B,SHMT1,GALC,APPBP2,TMUB1,GID4,PPT1,RNF5,HECW1,PSMD3,PSMD4,MME,CYP3A5,DNAJC10,STUB1,FEM1A,DDAH1,ABHD17A,SH3BGRL,VPS28,NSFL1C,BCKDK,BAP1,ASRGL1,NUDT19,PMAIP1,CHMP2B,PNPLA8,TP53INP2,CHMP2A,PSMB6,IFI27,HM13,ANAPC2,JKAMP,DNAJB2,PSMB2,UBE2S,ECRG4,MMP20,DNAJC3,ABCC2,SMURF1,PSMB11,MAEA,MTAP,UBE2B,OGDHL,RHOBTB3,USP38,ENPP4,HEXA,TOM1L1,LAMP2,PSMB7,UBB,CRMP1,CHMP1A,MAGEC2,CHAC2,UBE2K,SUCLG2,RNF14,UBE3A,ERLIN2,PELI1,KLHL25,PSMA6,HECTD3,RNF122,PPP2CB,PNP,OVGP1,ENO1,LDLR,DHPS,PSMD7,SYVN1,PSMA3,ACER3,GSK3A,DERL1,FBXL19,TSG101,PCSK9,PLA2G5,SKP1,PSMC3,PLAA,UBE2N,UBE2D1,TRIM24,XBP1,TOLLIP,SLCO2B1,SLCO1B3,SPSB1,PSMB3,SEC61B,CTNNB1,TNFAIP3,CTSK,HYAL2,GID8,GPT,SNX5,RNF103,UBE2W,DIO3,PPP1R11,FEM1C,UCP2,PSMD12,PSMA5,WDR77,FBXO9,CALR,PSMA4,ARMC8,HSD17B10,PSMD6,RNF128,RPS27A,UBA52,DDI1,GPC1,UBXN6,SELENOS,PFKFB2,FKRP,HERC4,UBE2G2,AKT1,SIAH2,TMEM199,SAMHD1,RNF115,BNIP3L,PPM1K,SMUG1,CCAR1,SPSB3,LYPLA1,PDE1B,NFE2L2,HNMT,FBXO7,NUDT16,PGK1,AREL1,CAPN2,CRYM,FBXO44,ZNRF1,CCDC47,CUL3,KLF1,PSMD1,TRIM3,FAH,RNF148,MAN1A2,TRIM45,CACUL1,PGM1,LYPLA2,DLST,ADRM1,ZFAND2B,DBT,FBXL3,DTL,RNF146,SPOPL,NUDT4,CDC23,RNF121,CHDH,UTP25,ANKIB1,PDE4B,TRIM21,RNF41,SQSTM1,XPNPEP1,EXT1,SLC25A21,PSMB4,ARG2,UBXN2B,CLPX,FBXW4,CHI3L1,DISC1,PSMC5,SLC25A44,PML,PDE2A,NUDT9,RMND5B,RNF10,URAD,VPS54,RNF26,BPGM,ACAT1,RNF40,CD2AP,NUDT12,APOBEC3A,MYLIP,ENTPD4,CCNF,USE1,NAE1,TRIM32,UBE2L3,GLUL,ABHD16B,ELOC,KBTBD6,BIRC2,PSMC4,NT5C2,UBAP1,SARM1,KCTD10,FBXW7,HDAC6,APOBEC3C,PSMA1,CLU,PSMC1,BFAR,DERL2,UBL4A,ANAPC13,SDS |
| 8.065e-10 | -20.94 | RPS24 (ribosomal protein S24) | protein interactions | 6229 | 489 | 199 | 19454 | 5460 |
TOP2B,RPL31,UTP25,HNRNPDL,RPS4X,H1-6,KRAS,MSX2,RPS7,EEF2,SUPT5H,RPL18,RPS23,EED,SRSF1,CCT7,LYAR,RPS10,ISG20L2,DDRGK1,NGDN,CTNNB1,CPEB1,RPL6,WWP2,DDX50,MAGOH,DRG1,AGR2,RPS28,PYM1,UFL1,PIH1D1,EIF4B,GTF2F1,CMTR1,RPL10,PSMD1,BTF3,MYC,H1-1,RPS26,ATG3,H1-10,FTSJ3,DHX9,RPL3,SNIP1,RPL17,MEPCE,RPSA,TP53,UBL4A,SRFBP1,STRBP,RBM34,DNAJC2,TFCP2,SURF6,RBM42,DKC1,RPS27L,FZR1,RPS16,CAND1,E4F1,CSNK2A1,COPS5,ENY2,RPL10A,RPS2,TAF9,SNRNP70,RPL24,RNF113A,BAP1,RPL27,ZC3H15,RPS15,WDR3,FGF13,KLF4,HEXIM1,RPA2,MACROH2A1,PHAX,RPS3,PSPC1,SF3B6,DYRK1A,SMURF1,RPL10L,PCBD1,RPS17,RPL7A,NDUFAF2,RRP7A,UBE2H,RC3H2,SLC25A5,RPS27A,G3BP1,TNF,RPL29,MAK16,B3GNT2,RPS11,CHMP4C,EZH2,RPLP2,RPLP1,HP1BP3,PHB1,RPL9,RPL8,BUD31,SPTAN1,RPL7,RBIS,NOP58,MAP3K14,PRPF19,RPL23,MRPS26,ZCCHC9,RNF10,TXNL1,UPF3B,G3BP2,COIL,NOP53,GKAP1,MFAP1,LARP4B,EMC9,SEC61B,RPS9,RPL37A,FAU,RPL19,RPL35,RPS29,PRPF31,ZNF668,CUL2,CUL3,ACO2,RIT1,RPS5,BRCA1,RPL23A,NKRF,RPS13,MRPS18C,VRK1,HUWE1,CTNNBL1,RPL15,EEF1A1,SRP72,ILF2,PWP2,KRR1,RCHY1,RPL12,HDAC6,SPATS2L,MOV10,MPHOSPH10,SQSTM1,MTDH,PNO1,SIRT7,PPM1G,RPA3,BRIX1,AATF,HMGB1,RPL4,FBXW7,EIF3J,KLF12,EDF1,RPS14,RPL26L1,RPLP0,H2AC7,RPS12,RPS20,PRKRA,METAP2,EIF4A3,CCNF,RPL22,NDN,TUFM,PPP1CC,USP14,FBXO7 |
| 8.085e-10 | -20.94 | cell death | biological process | GO:0008219 | 1091 | 412 | 18204 | 5365 |
BECN1,TOPORS,SNAI2,LTBR,FIS1,DICER1,ADAMTS20,CHST11,PAEP,CSNK2A1,CTNNA1,BAG3,ERO1A,SOX9,FOSL2,LTA,PRKCB,NCKAP1,MIR29C,NLRP6,ING5,DDIT4,HAND2,ELMO2,CEACAM5,DHX9,FEM1B,GLRX2,FGF10,SMNDC1,NUDT2,EMC4,KRAS,NOTCH2,PLSCR3,CRIP1,POLB,IL1A,TGFB2,PAK6,IGFBP3,NLRP9,PSEN1,ARL6IP5,RPS27L,ATG9A,HTRA2,ZMPSTE24,MYD88,IFT57,BRCA1,GADD45B,CDKN2D,PIM2,CD28,TAX1BP1,MEF2C,TNFAIP8,EFNA5,CAV1,CDIP1,HEY2,IRF3,HSP90AA1,RNF34,AKAP1,DAD1,STK3,PDCD5,HNF1B,BCL10,IL12A,CDK1,CNTFR,MYC,SNCB,IER3,GGCT,FLCN,SFRP1,MAGEH1,DAPK1,PPIA,PLEKHO2,CRYAB,NUPR1,ZFAND6,PEG10,TLR3,DYRK2,RMDN3,DLX1,ALDH1A3,ARF6,EXOC5,GAS2,FOXC2,PLSCR1,MIEN1,BCL7C,NEFL,PRKCA,CXCR3,RNF144B,MIR17,XAF1,NLRP3,AIPL1,CASP4,RNF152,TNFAIP1,DAP,CTTN,RB1,CITED1,ADNP,NLRP2,INPPL1,PSMD10,TOP1,CFDP1,SH3GLB1,RBM5,CDKN1A,ZNF622,CIDEB,ATG3,CXCR4,PYCARD,HRAS,RHOB,MZB1,PLEKHF1,BCL7B,DFFA,DNAJC10,EPHA2,MINDY3,ELMO1,CDK5,SLC25A4,TRAF1,MSX1,TRAF2,PDIA3,EDA2R,RPS3,TNF,CX3CL1,RAF1,IL10,MUL1,LIPA,FATE1,HELLS,CDKN1B,STK24,FAF1,NCSTN,IL7,NR4A2,CLN8,CUL2,RAD21,EPO,HINT1,GAPDH,SIAH1,TMEM14A,JADE1,TFPT,DNAAF10,GHITM,IFI6,EVA1A,DDIT3,ITGAV,PCGF2,PRDX2,EMP3,ADORA1,CSRNP3,MITF,SOD2,FHIT,DDX5,MIR34A,UBE2D3,API5,TNFSF10,MDM2,BLOC1S2,RRAGA,STK4,ERCC3,TP53,MAP1S,CTSC,FKBP8,MAEL,CAAP1,MSH6,PAK2,STK26,TGFBR2,IL2,SOD1,RRN3,CRKL,SIVA1,XBP1,HTRA1,FAS,CD14,MLLT11,KIT,CDK5RAP3,BLCAP,PRKCE,TMEM219,GSK3A,BCAP29,G0S2,KRT8,BAD,DEDD,TUBA1A,BCL2L1,JAK2,PTEN,STXBP1,PCSK9,GABARAP,SMAD4,WNT7A,AIFM1,AKT1,DELE1,SIAH2,IL1B,CTNNB1,TNFAIP3,SLC1A1,VDR,NPR2,BAK1,CTSK,KLK5,CYFIP2,GPX1,NFKBIA,EP300,PTRH2,VDAC2,PDCD10,SGMS1,DIO3,BOK,NSG1,MSX2,SFN,IFNA2,MIR21,TNFRSF1B,KCNIP3,RTN4,EMP2,ZBTB16,UBE2B,MCL1,TIA1,OPTN,BAP1,PMAIP1,CASP12,GPR65,ELK1,IFI27,NOA1,BCL2A1,EDNRA,TRAF7,DAPK3,PAK5,AKT2,PPP2CB,MX1,HSPD1,ERRFI1,VDAC1,DRAM1,TP53INP1,TRAF3IP2,BAX,STAMBP,IL6,AHCYL1,ACAA2,RTKN,MMP9,GADD45G,THOC6,PEA15,ACVR1C,VPS54,PPIF,SYCE3,PLAGL1,NINJ1,NPTX1,CD38,CD2AP,DMPK,C1D,GSKIP,ZDHHC16,TLR2,GADD45A,NDP,NAE1,CYP1B1,SPATA2,NFKB1,CRADD,KCNJ8,MAP2K6,IL2RA,CHI3L1,PML,HINT2,NKX3-1,S100A8,EAF2,STK11,CCAR2,CLU,NLRP1,BFAR,SAV1,ACVR1B,RALB,TMBIM6,GPAM,PDCD1,BIRC2,EGLN3,SELENOK,IFIT2,CD2,NAIF1,LMBR1L,SMAD3,CSRNP1,PARP2,IFI16,AREL1,TNFRSF9,BEX3,NBN,PIK3R1,NR2E1,CUL3,DNAJC5,IRF1,BRMS1,BMPR2,KDELR1,EI24,CD248,VEGFA,PPM1K,BNIP3L,MIR29A,CCAR1,TICAM1,PRELID1,MRPL41,ARHGEF6,IVNS1ABP,ZMAT3,TRIM21,PIK3CG,ATF4,RNF41,FASLG,SQSTM1,PMP22,FAIM,KCNJ11,TNFSF12,RB1CC1,SRGN,SST,FAM162A,ADRA1A,G2E3,PPID,ANGPT1,TRIM35,ROCK1,PDCD4,THOC1,MEF2A,ETV6,TMEM117,BIRC5,PIK3CA,CD47,TAF10,DYNLL1,TCIM,IFNG |
| 8.398e-10 | -20.90 | CS (citrate synthase) | protein interactions | 1431 | 454 | 187 | 19454 | 5460 |
ETFB,NUDT19,PDHA1,NDUFA12,KGD4,HNRNPDL,LAMP2,MRPL9,NDUFV2,AGR2,YWHAB,HSPB1,HNRNPL,LYRM2,PNPLA8,LAP3,ISCU,MRPL12,NDUFAF3,MRPS18A,PAK2,NGRN,HDAC5,HSPA8,NDUFS2,PHB2,OXCT1,MRPS7,MYC,HNRNPAB,CUTA,HMGCS1,MRPS25,MDH1,TACO1,MTG1,DLST,CCDC90B,TRMT11,MRPL13,ATP5F1B,ATP5PB,UBL4A,MRPL47,HADH,METTL15,ACADSB,TAB2,MRPL52,ATP5PF,MRPS18B,THG1L,IDH1,REXO2,MRPS33,PDE12,MEPCE,COX5A,LYPLAL1,SHC1,TMEM70,TRMT5,USP15,SDHB,COQ8A,SSBP1,MRPS9,UBE2N,COX4I1,MGME1,NDUFAB1,MRPL10,MAEL,QRSL1,RPA2,SPRYD4,IDH2,TWNK,GFM1,DLAT,NME4,MRPL40,MRPL41,GRPEL1,NDUFAF2,GSTK1,MRPS16,CHCHD4,OAT,UBE2H,UQCRC2,ACOX1,MRPS28,CEP41,SMURF1,SUCLG2,HSDL2,EZH2,NDUFS6,PREPL,HSPD1,THNSL1,HINT2,COX8A,MRPS11,ATP5F1D,ETFA,MRPS17,MTRF1,CLPX,STOML2,MRPS35,MMUT,ZNF207,RHOG,MRPL18,MRPS26,PHB1,GATD3,EGLN3,NDUFS8,PRDX3,IDH3B,ATP5PO,CRYAB,NDUFA5,ATP5IF1,HADHA,MTG2,AUH,ACO2,TXNRD2,CUL3,PYCR1,PMPCA,AK3,NOA1,HTRA2,ENO2,MRPL23,DYNLL1,NDUFAF4,SNRPB2,MRPL11,NDUFA2,PPIF,BCS1L,NDUFS3,SOD2,MRPL49,HSD17B10,AGA,HUWE1,TF,VRK1,HSPE1,FASTKD5,MRPL22,MRPS18C,ABHD10,MOV10,GRSF1,CHID1,CDCA3,LDLR,MRPL50,ATP5PD,DBT,MRPL24,MRPS23,ATG16L1,CRAT,MRPS34,METTL14,MTRES1,RPA3,IDH3A,EIF5B,MRPL17,MRPL20,POLDIP2,PYCR2,ATP5F1A,TUFM,CCNF,ACAT1,SLC25A4 |
| 8.398e-10 | -20.90 | PSMC5 (proteasome 26S subunit, ATPase 5) | protein interactions | 5705 | 454 | 187 | 19454 | 5460 |
CBL,CTNNB1,DYNC1I2,SUMO2,MRAS,PSME2,HOMER3,MOB3C,TAF10,SOX2,PSMA1,KRAS,HNRNPF,PSMA2,SSNA1,RUVBL2,BCL7B,ABCF1,PSMD14,PSMD1,BAG3,CREBBP,MYC,APOBEC3B,PSMA4,RORB,PSMB6,APEX1,ESR2,PSMD4,PSMD6,PRMT5,LMBR1L,CSNK1A1,PSMB3,PAFAH1B1,DDI1,UFL1,EMC1,HDAC5,HSPA8,HERC3,FOS,MAP4,USP15,PSMG2,CCDC92,ZFAND2B,COPS5,PPM1D,TPM3,ADIPOR2,PLEKHO1,CDC5L,FZR1,GTF2B,PSMC3,NUPR1,TMEM31,CAPZA2,INSIG2,TP53,MEPCE,EDEM2,FKBP8,PSMA5,MAP1B,PSME1,ATP1A1,PDCD4,UBE2H,RC3H2,PSMB2,AKT1,FGFR1OP2,SMURF1,NR1I2,CHMP5,ADRM1,PSMC5,MOB4,UQCRC2,PSMA6,UBE2M,TFIP11,HEXIM1,ACACA,RPA2,HBB,CDC42,GABRA1,CD2AP,PAAF1,CFTR,HSPA5,NR1I3,BAP1,PML,RB1CC1,MED4,ELP6,PSMD10,TRAF6,PSMD3,EGLN3,KIF3B,CCAR2,COPS2,PSMB5,PPP2CB,PSMB4,PHB1,AZIN2,RPN1,EZH2,SCHIP1,PPP2R1A,RPL29,ASPM,VDR,RPS27A,PSMD12,COX8A,SKA1,UBE3A,BAX,SP1,BRCA1,ALDH1L1,CUL3,SIAH1,TUBB,SNRPD2,PSMB7,CDKN1A,WDR77,PSMC1,CRY1,TRIM5,PSMA3,PMAIP1,ECD,PSMD7,HDAC6,ERCC3,CDK9,PTP4A3,MDM2,PSMB1,PTPN1,RAD23B,PSMB9,RPS13,VTA1,FBXO25,HUWE1,SEM1,HAPSTR1,IGF1R,HSD17B10,EMC2,SIKE1,FBXO7,AR,USP14,VIRMA,NDN,CCNF,PDCL,SHOC2,PTP4A2,JUP,METTL14,GRM2,UBLCP1,PSMC4,RPS14,UBA52,ATG4C,DESI1,SMC4,FBXW7,SQSTM1,SOD1,RPA3,IDH3A,SIRT7 |
| 8.590e-10 | -20.88 | NCBP1 (nuclear cap binding protein subunit 1) | protein interactions | 4686 | 336 | 146 | 19454 | 5460 |
AATF,HSPA5,EIF4E,HMGB1,SIRT7,PML,RPA3,PPM1G,SNAPC1,HEXIM1,RPLP0,DYRK2,ZNF574,METTL14,RPA2,CFTR,AGO1,SF3A1,ATG16L1,VIRMA,SRPK2,SMURF1,ADRM1,TRIM24,PTEN,RPS20,PHAX,EIF4A3,CCNF,PSPC1,RPS3,UBE2H,RBM7,ELAVL2,RC3H2,IVNS1ABP,TXNIP,KPNA6,CCNB1,CDC16,MEPCE,RNF20,KPNA2,HUWE1,DHX9,HSD17B10,SNIP1,CERK,NUPR1,ILF2,DUSP1,APOBEC3D,UBL4A,RBM42,NCBP2,THOC1,TOP1,CAND1,FZR1,RCHY1,ALYREF,EIF4E2,PTPN1,SYNCRIP,TSNAX,KPNA1,FBXO34,SNRNP70,EXOC2,SMAD4,GAPDH,MPG,COPS5,MOV10,NFKB1,ZDHHC17,STAU1,UFL1,EP300,TTC1,SF3B1,HSPA8,UPF3B,NKAPD1,THOC3,DDX39B,SNRPA,MED23,PPP1CB,ESR2,PSMB6,POLR2B,ACTB,RPS9,SNRPD2,PRMT5,RAN,RSRC1,THOC6,RIT1,RBM27,ATG3,SNRPB,RNF40,HNRNPAB,CUL3,HNRNPC,MYC,SSRP1,POLDIP3,AP1M1,RUVBL1,NUP42,HNRNPF,PSMA1,KRAS,RUVBL2,RPAP3,HNRNPA2B1,PABPC1,THNSL1,SDHC,RHOBTB1,PDHA1,PAIP2B,GFPT1,ACTN4,E2F4,SUPT5H,RAF1,SNX2,SNRPA1,MPP1,LYAR,PAIP1,HNRNPL,EED,PHB1,THOC2,HNRNPD,RB1CC1,AGR2,DDRGK1,XPO1,HNRNPA1,IFI16 |
| 8.666e-10 | -20.87 | IGF1R (insulin like growth factor 1 receptor) | protein interactions | 3480 | 460 | 189 | 19454 | 5460 |
HDAC6,ESYT1,OSBPL8,EHBP1,HACD3,SRPRA,PTPN1,SMAD3,SEC23A,CDCA3,TES,PRNP,NAT2,CAV1,MDM2,CCDC47,DOK5,MTA3,SOCS3,EEF1A1,ADAMTS1,TRAPPC13,IGF1R,SERTAD1,ERLEC1,SOCS2,ARF4,DUSP21,CSK,ATP5F1A,ARFGAP3,SDF2L1,EPHA2,PIM2,EIF4A3,GXYLT1,GAB1,MSN,PTEN,DNASE1L1,GANAB,KCNIP3,SEC63,DUSP10,GNAI2,VIRMA,FERMT2,UBB,SEC22B,ARHGAP1,SPR,COQ8B,CNP,KDELR2,HSP90B1,CDK1,JUP,MET,CYP17A1,EGFL7,CST11,SYVN1,PIK3R2,YKT6,NF2,PSMD3,PIK3R1,CDK5RAP3,CDKN1B,HAX1,PSMB4,XPO5,GJA1,SNX2,SNX1,DNAJB9,OS9,WDR44,B3GNT2,RPN1,EZH2,STIM1,NDUFA4,SLC25A5,PCNA,SLC39A7,JAK1,GRB10,RAB11A,CUL3,PIK3R3,VEZT,NIBAN2,GGH,OTUD7B,YWHAZ,RHOB,RIT1,KLK5,SCFD1,HSP90AA1,ARF1,JAK2,MAD2L1,EHD1,VAPB,FKBP10,DNAJC3,HADHA,DUSP26,DPP4,SHC1,AKAP8L,UBE2N,FCHO2,GRM1,RPS16,CAND1,FIBIN,CDK4,TP53,SNAP29,SFTPC,TFRC,TRAFD1,SRPRB,DUSP19,PTPN11,AKT1,DNAJC10,CHRAC1,CALU,SNX5,RPS3,EIF2S2,PSMC5,SEC61A1,SRC,DUSP18,AKR7A2,NTPCR,IGFBP3,FGFR1,UBE2M,BAP1,SEPTIN6,ELOF1,GPIHBP1,HDAC3,CLU,HSPA5,DDRGK1,CTNNB1,XPO1,YWHAG,NCK1,YWHAB,CBL,PTK7,EED,RAB1B,HNRNPL,EIF2S1,HSP90AB1,TOP3B,EEF2,CRKL,GHR,CDK5,IGF1,RUVBL1,KRAS,RPS4X,SFN,TBCE,LAMTOR1,SERPINH1,DOK4,FBXO22,DUSP14,CNPY3,MAP2K1,CTBP1,EP300,HSPA8,PHB2,NDUFS2,RNF41,ITGAV |
| 8.881e-10 | -20.84 | TRA2A (transformer 2 alpha homolog) | protein interactions | 29896 | 322 | 141 | 19454 | 5460 |
DHX15,SRSF10,MIR9-1,BUD31,PAIP1,HP1BP3,MIR214,EED,MIR7-2,SRSF1,MAGOH,MIR140,MRPS26,MIR1-1,MIR221,RB1CC1,MIR31,MRPL18,DDRGK1,MIR29C,YWHAG,WWP2,RPL6,MRPS35,MIR143,SSRP1,SRSF4,MIR155,H1-6,MRPS11,SRSF8,SRSF7,MIR206,EWSR1,PABPC1,MIR9-2,SMARCB1,CHMP4C,EZH2,MIR222,NCSTN,RAF1,FEN1,CSNK1E,ESR2,MIRLET7D,MIRLET7B,ZNF22,MIR363,MRPS25,NOA1,MIR98,BTF3,CUL3,HNRNPC,MYC,MRPS7,SAP18,STAU1,UFL1,TRA2B,EP300,MRPL34,NMRAL1,NKAPD1,SNRPA,NGRN,NCOA5,LARP4B,PABPC5,CDC5L,ZBTB2,MRPS23,MIR429,MIRLET7G,TOP1,MRPL50,MIR25,CDK6,MIR106B,MRPS9,NAP1L5,SRP14,BRD3,MIR34A,SNRNP70,APOBEC3F,COPS5,MOV10,MIR16-2,MEPCE,MRPS18C,SRSF12,MIRLET7C,THRAP3,CDK2AP2,MRPS33,SEPTIN7,MRPS18B,ZC3H11A,SNIP1,NUPR1,GFM2,IK,MIR17,CDK8,MIR20A,APOBEC3D,MIR200C,MIR15A,TP53,SRPK2,MRPS21,MAGOHB,PHAX,EIF4A3,SF3B6,MIR16-1,CASC3,PPIG,XPOT,ELAVL2,MIR145,PPP1CC,MIR107,HMGB1,MIR7-3,MIR34C,MIRLET7I,CLK1,TWNK,MIR205,MIR7-1,RPL26L1,DYRK2,MIR21,MIR1-2,SNRPN,SF3A1,MIR34B,ATG16L1 |
| 8.974e-10 | -20.83 | Prkab1 (protein kinase AMP-activated non-catalytic subunit beta 1) | protein interactions | 83803 | 90 | 53 | 19454 | 5460 |
HSP90AB1,SNRPD3,RPS10,PHB1,RPL8,RPL12,RPL10A,RPL23,DRG1,RPS2,RPL24,TPM3,RPS4X,RPS13,RPL28,RUVBL1,RUVBL2,RPL23A,PABPC1,RPL31,RPS11,ILF2,PRKAG1,TUBB4B,ACTR1A,EEF1A1,TUBA1A,RAF1,RPL22,RBBP4,TUBB,ACTB,ATP5F1B,RPS9,RPL37A,RAN,EIF4A3,SF3B6,RPS3,HSP90AA1,IGF2BP1,MYO6,NONO,RPS17,RPL26,RPL7A,PHB2,DDX5,HSPA8,MYL6,PPP1CB,MYL12B,RPS14 |
| 9.109e-10 | -20.82 | cellular response to stress | biological process | GO:0033554 | 1589 | 575 | 18204 | 5365 |
POLL,FAS,EIF2AK2,SEC61B,XBP1,AATF,HPF1,CREBZF,NRBF2,TERC,UBE2N,CARTPT,SOD1,SUSD6,CCND1,PHF1,STK26,MIRLET7B,ATP5IF1,MSH6,USP3,FGF1,PCSK9,MORF4L1,BCL2L1,JAK2,PPP5C,BAD,DERL1,MIR448,SMCHD1,SYVN1,CDK5RAP3,PAXX,PRKCE,ASF1A,CRY1,EGLN2,MIOS,DYRK1B,DELE1,NOP53,AKT1,AIFM1,KCND2,PYCR2,NDNF,ELAVL4,UBE2V1,LMNA,CEBPE,RNASEH2C,UBE2G2,CDC7,UBE2V2,RPL26,INO80E,TANK,SELENOS,UBXN6,GABARAP,PDIA2,AGR2,SIRT7,NPC1L1,CALR,BOK,RNF103,ROMO1,EP300,NFKBIA,UCP2,RFC3,UBE2W,PDCD10,KICS2,MT3,GPX1,SLC1A1,TNFAIP3,SHLD1,BACH1,CTSK,TXN,BAK1,MAP1B,MCL1,RGCC,UBE2B,TNFRSF1B,ATG7,HDAC3,RWDD1,ECRG4,DNAJB2,JKAMP,DNAJC3,HM13,SFN,SELENON,GPX5,MGME1,MLH3,AQP2,BCL2A1,SAR1B,EDNRA,RRAGB,APTX,MAD2L2,SIN3A,LIG3,GNL1,RMI2,PMAIP1,SRXN1,OPTN,MIR210,CD36,BABAM1,MPV17,HSPD1,CBX3,DMAP1,PPP2CB,TOP3B,ACTL6A,JUNB,MORC2,CHCHD6,JUN,SLX1A,FLOT1,TENT4A,PPARA,GPR37L1,PRELP,OXSR1,PPP4C,UBE2E2,MCM6,ERLIN2,DDX1,IMMP2L,POLD4,DNTT,MYO6,FOXP1,STOML2,YWHAG,CETN2,MMP9,BGLAP,MIR107,ACAA2,MIEF1,BAX,TP53INP1,LAMP2,IL6,TRAF6,GADD45A,G6PD,CYP1B1,NAE1,NDP,HP1BP3,CD2AP,ZDHHC16,XRCC5,CTLA4,PPIF,PACRG,PICK1,PML,RPAP2,NUP62,MAPKAPK5,KIN,IGF2BP1,NGB,MAP2K6,CHCHD2,H2AC25,FOS,EIF2S1,TERT,KCNJ8,CRADD,NFKB1,RALB,DERL2,TMBIM6,KLF10,HILPDA,RINT1,OMG,TMIGD1,STK11,CREB3,CCAR2,AKR1B1,ATF3,NKX3-1,FOXA3,POLDIP2,FBXW7,SGF29,HDAC6,PRR5L,PARP2,DCUN1D5,STC1,SLC7A11,SLC2A1,TEX264,EGLN3,SELENOK,POLD2,TAF9,GLUL,KMT5B,TERB2,MAN1A2,YWHAZ,PIK3R1,CCDC47,VKORC1L1,PIK3R2,SSRP1,CUL3,GORASP2,EIF2B5,FBXO44,NBN,IFI16,SLC52A3,PGK1,TOMM7,TFIP11,RRM1,NSMCE3,PRMT6,NFE2L2,BNIP3L,PDIA6,SAMHD1,SMUG1,ALKBH2,BMPR2,VRK1,VEGFA,SLC38A2,SRC,DAG1,WRAP53,SMARCA5,MGARP,PRDX1,GTF2H2,GPX7,NRDE2,FAM162A,ATF4,MCM3,MIR140,TFEB,TRIM21,SQSTM1,INSIG2,PHB2,HIKESHI,ZMAT3,RNF121,TCIM,APEX1,MACROD1,TMEM117,GNB1L,GPR37,MEIOB,DTL,PIK3CA,ARMT1,STAU1,OARD1,PRKRA,ERO1A,FEN1,CTNNA1,BAG3,TNR,BAZ1B,CBL,MTARC2,NFE2,CPEB1,CSNK2A1,MIR20A,CDK7,DNAJB9,UBXN10,PTTG1,TOPORS,BECN1,LRRC8C,CDC5L,GAD2,OS9,MACROH2A1,PRPF19,KDM1A,NABP1,MIR200C,CRYGD,IRF7,EDEM1,SUMO1,NUCKS1,RNF126,SLC25A24,PAGR1,MAP1LC3A,CCS,MAP2K1,SDF2L1,GSTM2,RPA3,HSBP1,GLRX2,PEX13,MSL2,RMI1,RFC2,MCM8,RNF167,OSER1,AP5S1,FAM8A1,RNF8,DDIT4,STAT6,CLPB,MAP2K3,IL1A,GTF2H5,KLHL15,ALB,CRIP1,TMUB2,POLB,KCNMB1,NUDT2,ZBTB38,NCK1,IL18BP,GJB2,SESN3,PCNA,GTF2H4,SERPINB6,SLC38A3,BRCA1,HTRA2,MDC1,SOCS5,GFI1,HSPA5,ZMPSTE24,PTN,RNF113A,NUDT1,DGCR8,RPS27L,ARL6IP5,PSEN1,MIR146A,AQP3,FXN,POLR2I,CDIP1,DCTPP1,THG1L,CAV1,PRDX4,RBBP8,MEF2C,MSTN,CDKN2AIP,RUVBL2,ING2,ERLIN1,CDKN2D,HSP90AB1,SHPRH,MAP1LC3B,SOD3,CDK1,MIF,WDR45,RNF34,SETD7,UBE2A,HSP90AA1,IRF3,DYRK2,HNRNPA1,MIR106B,FAAP100,GSTM3,ZSWIM7,FZR1,DAPK1,PPIA,FAF2,SLU7,TDP1,NUPR1,PRDX3,CRYAB,CSNK1E,RCHY1,MYC,IGF1R,MIR126,SFRP1,FLCN,IER3,NLRP3,RAD23B,CEBPG,NEFL,CFTR,PPM1D,MIR214,MIR17,UFM1,PSMD14,HSPB8,SLC29A1,EDEM2,NHEJ1,AIF1,HSP90B1,RFC4,SH3GLB1,CDK9,CIDEB,CDKN1A,USP16,CXCL10,FOLR1,DAP,CGAS,OGG1,LRRC8D,RNF152,CASP4,H2AX,SPINDOC,ADO,EPHA2,BCL6,INO80C,TOPBP1,HMGB1,TOP2B,DNAJC10,STUB1,PYCARD,HRAS,DUSP10,MAPK10,BATF,RHOB,KDM2A,TBC1D24,BCCIP,FBP1,PCLAF,RNF5,HINFP,CAB39,GINS4,TMUB1,MUL1,DDRGK1,HMGA1,RBBP7,EXD2,TNF,VAPB,PDIA3,RUVBL1,CINP,RPS3,RPA2,ERLEC1,TEX12,RFC5,FBXO31,CCM2,TRAF2,CBX5,ATP1A1,SESN2,NREP,SUV39H1,GABARAPL2,UFD1,TSPO,BTG2,NQO1,IMPACT,STK24,CDKN1B,MIR193A,CCNA2,SGTA,UFL1,SP1,PPARG,IKBKB,CHCHD4,FANCG,MNAT1,RAD21,RNF139,NR4A2,HMCES,ZNF668,EPO,EZH2,GABARAPL1,FAF1,EDEM3,PYCR1,FBXO22,LAMB2,PTPN1,HSPA8,SCAMP5,TMEM33,RAD1,COMT,PRDX2,MGMT,PCGF2,NONO,ALKBH3,POLE3,TFPT,DDIT3,TLR4,EYA3,KLF4,CLCA1,PTPN11,DCLRE1C,HUWE1,ERCC3,VCPIP1,MAEL,TP53,MPG,RRAGA,CXCL8,MDM2,MIR34A,SOD2,UBE2D3,ASCC1,MCM4,CYGB,APEX2 |
| 9.133e-10 | -20.81 | response to lipid | biological process | GO:0033993 | 862 | 335 | 18204 | 5365 |
RBFOX2,GPBAR1,WNT10B,USP8,TXNIP,SMYD3,ELK1,PAX6,ADCY3,CAV1,MEF2C,EFNA5,LDOC1,MSTN,RUVBL2,CDKN2D,UCN,CD80,CD36,MGST2,TACR1,MIR342,SMAD2,MYD88,MTAP,PLCB1,PCK2,TLR9,TNFRSF1B,HTRA2,SLPI,RWDD1,GFI1,ILDR1,MIR96,MIR21,CDC73,CXCL3,MIR146A,ATP1A3,AQP3,MSX2,CLDN1,MIR185,AKAP12,UBE3A,IL12B,RNF14,RORB,CXCL9,GNRH1,FOXP1,MIR223,BGLAP,MMP9,CD86,IFNAR1,PRDX3,CRYAB,PADI2,SOCS2,MIR142,PTGER2,EIF4E,FBXO32,IL6,CREB1,IGF1R,SFRP1,LDLR,BCL10,REN,FOXP3,IL12A,CD274,ERRFI1,LILRB1,KLF9,YWHAH,CYP26A1,ATP5F1A,CCL3,PELI1,PPARA,RXRG,CSF2,IRF3,ACP5,MIR187,GAD2,LRP6,TIRAP,OR51E2,PHC1,STXBP1,JAK2,PPP5C,BAD,DIO2,ACACA,IDH1,LTA,RAMP3,FOSL2,PRKCE,ADCY2,MRC1,HDAC5,PRKCB,EGLN2,GSK3A,IRF8,CD14,CCR5,SOX9,CBL,IL22,PID1,RPL13A,RPL27,XBP1,GPX4,CCL21,GRIA1,MIR20A,TADA3,HNRNPA0,ATP1A2,CYP1A1,AR,BRINP3,LITAF,MSN,CNR1,TRIM63,PLAA,TGFBR2,TGFB2,MAP2K3,IL1A,CALR,NFKBIA,PLSCR3,UCP2,LIAS,CXCL11,KCNMB1,OXTR,IL18BP,GPX1,GH1,TNFAIP3,FGF10,CTNNB1,GJB2,VDR,MAP1B,AANAT,GSTP1,PCNA,AKT1,FMO1,AIFM1,DKK1,IL1B,SPP1,TGFB3,P2RY4,CEBPE,MIR182,PTPN22,SLC6A1,WNT7A,NFKBIB,FAM107A,MTDH,CST11,HAND2,CXCL1,ADTRP,MBD3,ITGA2,FKRP,SELENOS,VPS4B,DDIT4,CCR7,CYP27B1,FGF23,ALPL,MECP2,ABHD2,AKR1C2,SLC6A4,PTGDS,TICAM1,EPO,AKR1C1,EZH2,ESR2,PGR,IRAK4,CHMP5,NQO1,NR2E1,MLC1,TSPO,RAN,CDKN1B,CDO1,CCNA2,PTGER4,CYP7A1,CXCL13,LIPA,OPRK1,PPARG,FZD4,CAPN2,IDO1,HTR5A,TAB2,BRINP1,CXCL8,MDM2,TAF7,LPAR1,PIK3CA,F7,CAMP,SOD2,TACR3,DDX5,IL13,GNPAT,CNP,PDCD4,DAG1,BRINP2,SRC,GHR,HSPA8,GNG2,PTGES3,MGARP,KCNJ11,UGT1A1,SST,PRDX2,TRIP4,COMT,MIR140,PDE4B,TLR4,INSIG2,FASLG,LEP,KLF4,TFPI,PHB2,FIBIN,MICB,SPHK2,LRAT,CDKN1A,WBP2,CXCL10,FOS,CCL2,TYMS,OPRL1,CITED1,OGG1,PTGER1,NFKB1,GPX3,KCNJ8,GPR83,TLR2,NLRP3,TRAF6,TICAM2,CYP1B1,FKBP4,NEFL,CD38,CFTR,THBD,MIR17,TRIB1,XRCC5,PDCD1LG2,MAPKAPK3,CDK4,FBXO3,CCL19,VPS54,H2AZ1,ROCK2,IL10,PTGFR,STC1,ADIPOQ,TNF,RBBP7,YES1,TFRC,PHB1,LY96,TRIM6,WNT2,HNRNPD,UBE2L3,CRHBP,ATP1A1,PAQR8,PLSCR4,CX3CR1,CLDN4,WDR83,PTK7,CD40,SYK,HMGB1,GNB1,STK11,PYCARD,STAP1,DUSP10,NKX3-1,NFKBIL1,TESC,S100A8,FBP1,HDAC6 |
| 9.137e-10 | -20.81 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1691 | 608 | 18204 | 5365 |
TICAM1,NFE2L2,IL15,TLR1,HSPB6,FABP5,SLITRK1,ALPL,MECP2,SMARCB1,BMPR1A,MTPN,VEGFA,SEMA7A,IL23A,BMPR2,EXOSC3,MIR29A,SETD4,NR2E1,PIK3R1,AFAP1L2,AMIGO1,OSM,GSTO1,CCL1,PQBP1,BRMS1,IRF1,BSCL2,NIBAN2,NTRK2,STIM1,FZD4,FLRT2,OPRK1,IFI16,TLR8,CTNNBIP1,IL17F,PIK3CA,CD47,TIAM1,F7,ELOVL3,PAFAH1B1,MIR34B,NLGN1,IFNG,GPIHBP1,MEF2A,ROCK1,RAB8B,LGR4,MIR143,CAMP,TACR3,IL18,TNFSF12,DAG1,MIR34C,SRC,ADRA1A,CD58,UTP25,CD40LG,LEP,CD200,PDE4B,NECTIN2,ATF4,THY1,PIK3CG,HCLS1,FOS,CHI3L1,DISC1,CLEC9A,CCL2,BMPR1B,IL2RA,JMJD8,CHRM3,MIR16-1,TERT,IL15RA,CD38,THBD,MIR222,TICAM2,CYP1B1,AGGF1,TLR2,FXR2,NLGN2,TRAF6,EEIG1,CCL19,RNF10,TLR5,LRRN1,LRTM2,DPP4,NINJ1,TBK1,CYRIB,TRIB1,MIR378A,XRCC5,VSIR,CD2,SPTBN1,ATRAID,PARP2,SCN3B,SMAD3,KMT5B,SLITRK2,WNT2,TRIM32,TUSC2,GPAM,TFRC,YES1,SELENOK,PRKAB1,NLRP1,HILPDA,SYK,CLU,KLF10,CD40,MACROH2A2,ACVR1B,TESC,NOG,FCGR2B,HDAC6,NKX3-1,NME2,STAP1,ADIPOR1,STK11,RIGI,SIN3A,PAX6,MAD2L2,WNT10B,FOXS1,MIR204,CLEC6A,CD80,CD36,MIR210,POLR3F,UCN,MIR33B,EMP2,RTN4,ADM2,HDAC3,MIR548C,SMURF1,PLCB1,TLR9,SMARCD3,TNFRSF1B,GLIPR2,RGCC,JAK1,GPRASP3,ZBTB16,MSX2,ANAPC2,LILRA2,MIR519D,FABP4,HADH,LPCAT3,MIR21,MIR30B,INHA,GPM6B,LRRTM1,STOML2,FOXP1,SLC7A1,MMP14,IL12B,FCER1G,DDX1,POLR3B,FGR,SLITRK5,HAPLN2,IL6,CSK,RSAD2,AGPAT1,ID4,ENPP4,GP9,MIR379,ADIPOR2,GADD45G,BTG1,CD86,ASPM,PNP,PLXNC1,OTX2,PRL,ACTL6A,MIR1224,DHPS,FUT1,HSPD1,ENO1,AKT3,FOXP3,CD274,ADRB1,HAX1,SPRY1,VEGFC,KLHL25,PELI1,EMC10,TMBIM1,FLOT1,SMARCE1,IFNGR1,JAK2,NRP1,TIRAP,MIR125A,NR1H2,FGF1,STAT1,PRKCE,GSK3A,LACC1,KPNA6,L1CAM,DIO2,CD34,G0S2,BAD,ADRB3,TNFSF13,XBP1,KIT,RLN2,FLRT3,EIF2AK2,CD14,MIR206,MIR221,MIR130A,IL2,TGFBR2,MIRLET7B,SS18,CCND1,CNR1,SOD1,CARTPT,SLC8A1,RND2,AR,DIO3,BRD9,UCP2,IGF1,SAP30,EP300,GRPR,KARS1,ASPA,MIR675,MAP1B,VDR,HYAL2,SHLD1,GH1,CTNNB1,RBBP4,SLC1A1,OXTR,TOX,RETN,CCL24,TMEM106A,WNT7A,PPP3CA,MIR182,IL1B,TGFB3,BMP1,AKT1,TLR6,PRMT5,ITGA2,SMAD4,GRB10,TANK,EPO,LUM,TPBG,C1QTNF1,HMCES,KPNA2,LGALS3,RAD21,APOC2,MKKS,TRIM15,GAPDH,CYP27B1,EGR1,TGFB1I1,MYRF,IL34,MIRLET7G,B2M,MIR195,CHRNA7,EZH2,CHRNB2,ITK,IL7,PDE9A,GAB1,TSPO,JUP,PRKCQ,CLSTN3,PPARG,UFL1,SP1,MIR30A,PTGER4,CXCL8,SDCBP,ACTL6B,CTSC,IDO1,CLEC7A,MIR1-1,IL21,IL13,LEPR,MIR34A,PRDX2,CRABP2,P2RY1,FGFR1,NKAP,TSHR,MIR99B,PPIB,SCAMP5,SGIP1,GHR,PTPN11,MIR590,KLF4,ZBED3,CCL11,ST3GAL4,TOMM70,TLR4,APLNR,TRIM27,DDIT3,ICOS,TNFRSF14,CDKN1A,SPHK2,ELOVL6,RAG1,ASIC2,ADNP,RB1,CTTN,NLRP2,LRRC4B,ZNF365,CGAS,MIR17,MIR214,GJA1,PRKCA,NEFL,ACVR1,CEBPG,NLRP3,AIF1,CCR2,F2,FOXC2,IRF4,RHOH,MIR657,BCL7C,PDCD1LG2,TNF,ADIPOQ,LBH,RBBP7,CCR3,ACTB,XCL1,ROCK2,IL10,RBPJ,BRMS1L,CX3CL1,SLC39A10,ATP1A1,MSX1,DBH,CX3CR1,TRAF2,MIR145,NMBR,TESPA1,FCGR2A,NKX6-2,AVPR1B,PHB1,RPS3,LY96,TRIM6,ING1,VAMP7,LRRTM2,DDAH1,MME,CD1D,BCL7B,HMGB1,RGS2,BCL6,CXCL12,PLAC8,ITGB8,CXCR4,EMILIN1,TBC1D24,RHOB,BATF,DUSP10,CD226,IL1RAP,TAPT1,LURAP1,LRRC24,AGER,ZNF304,HRAS,PYCARD,PLG,TYROBP,CAV1,ACHE,MAVS,CMA1,CBFB,CD28,RAB1A,PTPRZ1,BLOC1S3,ING2,EFNA5,MEF2C,RUNX1,IL20RB,SOCS5,IFIH1,MIR208A,IL4,NPTN,BRCA1,MIR31,TACR1,MIR342,SMAD2,MYD88,MIR324,CD46,CBLN2,MIR149,EGR2,PSEN1,LILRB4,CD81,NLRP9,CD4,PLPP6,PTN,CCL5,GPSM3,G3BP1,ZNF322,HCRT,EPHA4,TLR3,DEFB124,AKAP12,CREB1,IGF1R,FRMD8,MIR126,MYC,FERMT2,HSPB1,LRRTM3,MIR142,SLC20A2,MIF,CD83,CCL3,SASH3,ATP6AP2,APLN,CDK1,OSR2,LILRB1,MIR132,HTR2A,BCL10,DDT,INPP5K,IL12A,HEY2,SYNDIG1,IRF3,HSP90AA1,BTN2A2,CSF2,IL6ST,CFL1,OPRM1,TLR7,IRF7,IL5,SMAD1,KDM1A,MACROH2A1,MAP2K1,CCR1,PRKCB,PPP1CC,IRF8,CHGA,LTA,SAP30L,TOB2,OAS1,TRAF3IP3,CCL21,MIR20A,GHRL,PAEP,RHEB,SOX9,FZD3,TNR,DICER1,EFNB1,CBLN1,BECN1,ATP1A2,CD209,ACTA2,SLC6A3,KRAS,NOTCH2,HRH2,MIR144,TGFB2,IL1A,FGF10,LTB,IL2RG,NCK1,TF,CPT2,PTPN22,SPP1,FAM20C,VAMP8,DKK1,DHX9,ISG15,TPPP,STAT6,CCR7,SEMA5A,UAP1,GREM1,ADRB2,WASF3,HAND2,MTDH,CFAP20,PROX1 |
| 9.266e-10 | -20.80 | CCT6A (chaperonin containing TCP1 subunit 6A) | protein interactions | 908 | 540 | 216 | 19454 | 5460 |
KARS1,GAPDH,CSNK2A1,B9D1,SHC1,TUBG1,CD274,FZR1,CDC5L,TP53,RPSA,ACTR1A,TFCP2,METTL18,MAP1B,KHDC1,KDM4B,DYNC1I1,STRADB,CAPZA1,MEPCE,ETFBKMT,AKT1,MAT2A,RC3H2,RAP2C,UBE2H,ATP1A1,UQCRC2,MOB4,BUB3,CDC20,SUCLG2,SMURF1,SAMM50,RPA2,WRAP53,TRIM68,ACACA,HEXIM1,UBE2M,PML,NLE1,HCFC2,BAP1,HDAC3,HSPA5,ZC3H15,WDR55,PFDN5,IFI16,DCAF4L2,MAPK4,ACTR3B,DDRGK1,AGR2,DCAF5,DRG1,DUSP6,WDR82,EED,SUMO2,TCP1,DYNC1I2,HNRNPL,CCT7,TRMT61A,SOX2,ISG15,TUBA1A,HDAC11,DCAF8L2,TUBB4B,PABPC1,CCT8,CTTNBP2,ACTR1B,CDK5,KRAS,IMPA2,PFDN1,LDHB,KLHDC8A,PSMA4,APOBEC3B,MYC,PSMD14,FBXW11,CCT2,PELI3,PLA2G15,COP1,PSMD6,SNRNP40,ESR2,PPT1,PACRG,PIH1D1,EIF4B,DDX39B,EP300,RAP2A,DDX5,SF3B1,P4HA2,HDAC5,STAU1,UFL1,FNDC11,SUV39H1,CRBN,FGR,EEF1AKMT3,PTPN1,METTL6,CCT5,MAP1LC3B,MMACHC,ACTR2,KLHL26,PPP4C,GLUL,PC,HAPSTR1,DNAAF10,HUWE1,FBXO25,CIAO1,AR,FBXO7,STK24,SMAD2,CDC73,SMAP2,EIF4A3,TUBA1B,PTEN,UBASH3B,GANAB,ZBTB18,PPM1M,YES1,ARMC6,NDN,ABHD17A,VIRMA,PDCD5,TECR,CCND1,WDR5B,WDR83,GABARAPL2,METTL14,PDCL,IDH3A,PRPF4,RPA3,SQSTM1,FBXW7,IRF7,GABARAP,PRPF19,RAP2B,PPM1B,SKIC8,AHSA1,DCAF11,PHB1,PPP2CB,FOLR1,MAP1LC3A,IGBP1,DHX15,CETN2,EGLN3,RAF1,WDR37,GABARAPL1,GFPT1,NME1,NGB,EZH2,RPN1,POLR2C,RPS11,HECTD3,PCGF3,RBBP7,G3BP1,PCGF6,UBE2A,CUL3,RHOB,BRCA1,DCAF4,RIT1,ILK,PFDN2,ARF1,TUBB,ACTB,PRDX2,USP5,GNB1,ACTL6A,WDR77,ALKBH3,SLC25A3,FBXW4,DNAJC3,THOC3,PSMA3,CRY1,GPC1,PPP2R2C,UCHL3 |
| 9.318e-10 | -20.79 | P2RY6 (pyrimidinergic receptor P2Y6) | protein interactions | 5031 | 382 | 162 | 19454 | 5460 |
SEC63,JUNB,AANAT,TECR,COPE,ZNF622,PSMC5,CYRIB,CALU,XPOT,ATP1A1,DNAJC10,ATP1B3,CNNM4,HMOX2,PPP1CC,ATP5F1A,CIAO1,TMEM209,MARS1,SMC4,CERS2,GTF2I,SQSTM1,LSM12,HELLS,MAIP1,PPM1G,EIF2B3,HSP90B1,EIF3J,ST7,CFTR,SEC22B,EEF1E1,PSMC4,PCK2,COQ8B,NOP9,ATP5PD,EIF2B5,TMED9,COG1,CAND1,DNAJC1,RWDD1,COX4I1,HACD3,SDHB,SRPRA,TIMM8B,STT3A,PTPN1,OSBPL8,EXOC2,PSMD7,ESYT1,ATP1B1,ATP5MG,CALR,MSH6,FKBP8,NOC4L,KPNA2,CSE1L,ERLEC1,TRAFD1,EMC2,TMX3,CLPB,ATP5PF,PSMC3,PPP4C,SELENOF,MLLT11,TFRC,SURF4,UBE2V1,IPO8,CCDC47,ATP5PB,ALG5,TNPO3,NDUFAF4,CHP1,POLR2B,PSMB6,LGALS3,PSMD6,DYNLL1,ATP5F1B,SNRPD1,RAN,EIF3K,PELO,VDAC2,DNAJB6,SCFD1,PSMD14,MCM3,UFD1,PSMD1,RPL39,NOP16,UNC45A,PSMC1,PHB2,STAU1,EMC1,NDUFS2,UFL1,HADHA,ATP5F1E,ATP5IF1,ARCN1,SLC25A3,ATP5PO,TIMM13,QTRT2,SEC62,YIPF5,PGRMC1,H1-5,CCT7,OS9,ERLIN1,UQCRH,XPO5,GJA1,PHB1,PSMB4,THOC2,YWHAB,DICER1,HAX1,XPO1,YWHAG,YWHAH,PDIA3,PSMD3,RAB18,SACM1L,RFC3,PRPS1,RPS27A,PSMD12,VDAC1,KRAS,RBBP7,PDIA6,SLC39A7,RINT1,PLSCR1,SNRPE,PLD3,CYB5B,PTRH2,RPN1,ERLIN2,TMEM59,RANBP1,MACO1 |
| 9.444e-10 | -20.78 | HDAC2 (histone deacetylase 2) | protein interactions | 3066 | 822 | 309 | 19454 | 5460 |
EDC3,CSNK2A1,USP15,MAP4,KPNA1,SNRNP70,SMAD4,GATAD1,SYNCRIP,SLAIN2,MXI1,TMPO,BRMS1L,RPS16,FZR1,ZMYM3,SPRR1B,ACTR1A,ESS2,H2AX,TP53,NUPR1,PHC1,ZFP1,NFE2L2,CBX3,TFRC,TFCP2,CYBRD1,RPL3,ABCE1,MNAT1,H2BC14,MEPCE,PHF1,KPNA2,HNRNPK,H3C1,MORF4L1,FOXA3,SMARCA5,SUGP1,CDKN2AIP,UBE2H,IGF2BP1,CCDC174,ATP1A1,NR2E1,MECP2,MACROH2A1,ING2,RPS3,CREB1,CDC20,ROCK1,BUB3,CFTR,CCNH,PPP1R8,KLF4,E2F6,HEXIM1,UBE2M,GIT2,RPA2,IRF3,PML,BANF1,BAP1,MARS1,BCL6,HSPA5,STK38,KDM1A,CTNNB1,DNTTIP1,PFDN5,WWP2,RPL6,UBE2E2,CNOT2,DDX1,CDC23,ZHX1,S100A8,RFX5,EED,MAGED2,FUBP3,CCDC71,SIN3A,HSP90AB1,HMG20A,SUMO2,TCP1,EEF2,H1-3,SOX2,CRTC2,MAX,RPL18,MOB3C,MTA2,SMARCB1,H2BC1,RUVBL2,EWSR1,PRDM4,TOP2B,PABPC1,LSM14A,RERE,RUVBL1,SATB1,ZNF609,PSMA1,BAG3,CPSF2,BRMS1,BTF3,KANSL3,HNRNPC,MYC,CREBBP,SERPINH1,RBBP8,PHF21A,PRMT5,ZMYM2,NFKBIA,MIDEAS,PHF12,PAPSS2,ZHX3,ESR2,RPL10,APEX1,PSMB6,CBX5,TRIM29,SNRNP40,MATR3,NEK7,MRPL12,ZC3H14,SYK,CSNK1A1,NUFIP2,KLC2,MAP2K1,NACC2,MXD1,CTBP1,YAF2,EP300,DDX5,HSPA8,FAM50B,XRCC5,BMPR1A,SAP18,PHB2,UFL1,FXR2,SUV39H1,HM13,FOXC2,EI24,MOV10,NFKB1,EXOC2,EPOP,RB1,MYBL2,RCHY1,H2AZ1,ZBTB2,MDM2,TSC22D3,RPL15,EEF1A1,ING1,MAP2K3,CCT5,TBK1,MTA3,SAP30L,ALPL,DMAP1,PPP1R12A,SMN1,CDK2AP2,HUWE1,PPP1CC,RACGAP1,AR,NONO,KPNA6,RUNX1,ZNF687,SEC13,BAHD1,NCKIPSD,SMAD2,CDC73,TXNIP,MSN,ALB,GANAB,ENO1,EIF2AK2,CCNF,PELP1,VIRMA,DEK,CDK7,ELP3,CCNA2,EID2,SNAI3,UBA52,CCND1,TPT1,PCK2,ATG16L1,IFRD1,RARS1,CDR2,SNAI2,JUP,LMNA,DCTN4,SIRT7,PRPF4,RPA3,HELLS,SS18,MBD3,FBXW7,RPL4,SMC4,GTF2I,DPY30,HR,HMGA1,PRDX1,C2CD2L,CSTA,ATP6V1A,DHX15,SRSF10,MPP1,SAP30,GFI1,ACTN4,GFPT1,RAF1,ZNF263,GPBP1L1,RBPJ,CHMP4C,STIM1,EZH2,VPS33A,RPN1,ZYX,HSPD1,PCGF6,RAD21,OVOL1,CBX7,RBBP7,ZBTB16,G3BP1,MCM3,SMARCE1,SAMHD1,CUL3,IKZF2,GRB10,HSP90AA1,PFDN2,SP1,BRCA1,YWHAZ,FOXP3,RAN,BAD,USP5,RBBP4,ACTB,TAB1,LMO4,CDKN1A,EHD1,ACTL6A,H2AC1,LARP4B,FOXS1,RLIM,PSMA3,HADHA,SLC35F2,TXNL1,PRKD3,G3BP2,TNFSF10,PSMC1,TGIF2LX |
| 9.618e-10 | -20.76 | HSPE1 (heat shock protein family E (Hsp10) member 1) | protein interactions | 3336 | 272 | 123 | 19454 | 5460 |
FBXL19,CFTR,PCK2,ATG16L1,SPR,HEXIM1,UBE2M,MTRES1,METTL14,PGK1,GPX4,GFM1,SOD1,BAP1,UGP2,NTAQ1,CFL1,RGN,TUFM,UBE2H,PNPO,TRIM24,MSN,ACAT1,CCNF,OPTN,ENO1,UBE2L3,VIRMA,TXN,PPIF,EEF1A1,PGM2L1,TP53,MRPL11,CCT5,SOD2,CBX3,SOS2,ERG28,ABCE1,IDH1,TAGLN3,HINT1,HSD17B10,FASTKD5,GLO1,CALR,TLE1,DSTN,AKR1B1,DCK,SSBP1,AIFM1,CD274,ARL10,ESD,MIF,NEK7,SHMT1,FKBP1A,ADSS2,SAT1,DDX39B,PEBP1,EXD2,LYPLA2,MYC,AUH,MTG2,PMPCA,CUL3,HSP90AA1,CRMP1,RIT1,CCT2,CKB,PSMD14,ENO2,LRIF1,PARL,TAGLN2,TAX1BP1,SOX2,DSTYK,MSX2,RAF1,APTX,EZH2,IRF8,PIR,PLS3,PDHA1,HINT2,EWSR1,COX8A,HSPD1,ANP32B,IMMP2L,IMPA2,LASP1,UFM1,RBBP7,KRAS,PPIB,HNRNPA1,CTNNB1,DDRGK1,MTRF1,PDIA3,CLPX,AHSA1,CBL,GSTO1,RHOG,ZHX1,GATD3,SELENOM,FABP5,PPIA,STK3,HSP90AB1,SUMO2 |
| 9.687e-10 | -20.76 | Rpl35 (ribosomal protein L35) | protein interactions | 66489 | 250 | 115 | 19454 | 5460 |
BTF3,RIOK2,PRPF31,RFC5,RPS5,DNAJB6,GTPBP2,MED10,CIRBP,RPS9,FAU,EIF3K,RPL10,RPL19,LRRC8A,REEP3,RPL27A,TRMT112,MED23,LARP4B,CCDC86,EMG1,RFC4,PACSIN3,EIF3D,BTF3L4,DDX50,RIOX2,DDX1,RPL23,DRG1,EED,WDR6,MRTO4,PEG10,HMG20A,EIF2S1,FAM98A,RPS10,RPL7,KIF2A,BUD23,MED9,EIF1AX,GTPBP1,RTCB,RPS24,TRIP4,RBM3,HNRNPA2B1,RPS4X,SSRP1,RFC3,RFC2,G3BP1,RPS17,NONO,RPL7A,EIF3G,RTRAF,SRP54,RPS12,CCNF,PSPC1,STUB1,RPS3,BCCIP,JUNB,RPL22,DEK,ZNF622,RPL13A,RPP25L,GTF3C4,GTF2H4,RPS14,PIP5K1A,HEXIM1,TFB1M,MRPS34,TIMM23,MTDH,RPL27,BANF1,WDR55,NPM3,EIF5B,RPS15,RPL4,MPG,ERCC3,RPS2,CLP1,RPL24,SRPRA,RPL32,KRR1,CDK9,IFRD2,RPS16,MRPL50,ZMYM3,RPSA,SRP72,CHAMP1,RPL23A,DHX9,HSD17B10,NKRF,MEPCE,RPS13,RPL17,MNAT1,EIF3E,CNOT7 |
| 1.045e-09 | -20.68 | LDHA (lactate dehydrogenase A) | protein interactions | 3939 | 317 | 139 | 19454 | 5460 |
PPM1K,AHSA1,HNRNPD,AGR2,GSTO1,DDRGK1,HNRNPA1,RAB5C,PDIA3,HSP90AB1,PPIA,RAB1B,FAHD1,PHB1,MOB3C,CHMP4C,RAB6B,RAB4A,PDHA1,EZH2,MSX2,SOX2,MAPK10,ISG15,RAF1,B3GNT2,SAR1B,VDAC1,ETFA,TRIM37,TRIM26,MKLN1,ZC3H7A,PCNA,MDH1,HSP90AA1,BRCA1,ADK,UFD1,CUL3,LDHB,MYC,ESR2,USP38,TUBB,DYNLL1,PRDX2,ANAPC2,IRF2,ARF1,PIH1D1,CNDP2,ELOVL1,ACAA2,PPT1,PSMB7,STAU1,EMC1,PRCP,UFL1,EP300,AKAP1,RAB5A,PSMA3,HSPA8,NMRAL1,HDAC5,FOXP1,NME2,HDAC6,MIF,PRNP,CAND1,FZR1,DSTN,ARL10,EEF1AKMT3,CD274,SDHB,RNF8,GNAI3,PPME1,TFCP2,PGM1,HADH,TP53,RIGI,ARF4,CSE1L,AKAP12,HUWE1,RAB1A,FAF1,SORD,UBE2H,CDC73,SPOP,USP14,AR,CFL2,CFL1,CTSD,AKT1,FAH,SRPK2,BCCIP,VIRMA,SUCLG2,IDE,NDN,KCTD9,LDHA,PTEN,GSK3A,PAFAH1B3,ENO1,ALG2,OPTN,CCNF,STUB1,HEXIM1,UBE2M,METTL14,FGFR1,RPA2,LDHAL6B,CFTR,KCNJ11,SPR,ATG16L1,FBXW7,TCEA1,PRDX6,SQSTM1,PGK1,PML,RPA3,SOD1,BAP1 |
| 1.056e-09 | -20.67 | HINT2 (histidine triad nucleotide binding protein 2) | protein interactions | 84681 | 334 | 145 | 19454 | 5460 |
NOA1,MRPS25,PMPCA,PYCR1,AUH,MTG2,ACO2,MRPL16,MRPL23,ATP5F1B,NDUFAF4,CLIC4,PARL,CCDC90B,DLST,TACO1,MRPL13,ATP5PO,ARCN1,NDUFA5,MRPL12,NDUFAF3,PHB2,NDUFS2,HSCB,MRPS7,EXD2,ATPAF2,HADHA,ATP5F1E,TXNL1,RHOG,MRPL18,GSTO1,MRPS26,MRPS35,STOML2,MTRF1,CLPX,NDUFV2,MRPL9,HNRNPL,PNPLA8,NDUFS8,GATD3,PDHA1,NDUFS6,NUDT19,NDUFA12,ETFB,HSDL2,ATP5F1D,ETFA,KGD4,IMMP2L,MRPS17,PREPL,HSPD1,MRPS11,COX8A,MRPS16,GLOD4,OAT,PYCR2,NDUFAF2,TUFM,DDAH2,ENO1,MRPL53,ACAT1,MRPS28,IDH2,QRSL1,MRPS34,MTRES1,GSTP1,DDAH1,SPR,CNP,CFTR,CRAT,NDUFAB1,MRPL10,MRPL40,MRPL41,MRPL17,NME4,PDHB,MRPL20,POLDIP2,DNLZ,CRYZ,GRPEL1,IDH3A,SOD1,GFM1,PRDX6,DLAT,TWNK,TMEM70,PYURF,ATP5MG,COX5A,GRSF1,LYPLAL1,MRPL50,PRNP,MRPS23,MRPL24,DBT,ATP5PD,COX4I1,SDHB,MRPS9,HDHD3,SSBP1,NDUFS3,MRPL49,GFM2,JCHAIN,MRPL11,BPIFA2,NDUFA2,MRPL47,ATP5PB,CMPK1,BCS1L,PGM1,METTL15,GLRX5,PPIF,AURKAIP1,HADH,HSPE1,MRPS33,PDE12,MPST,MRPL22,FASTKD5,MRPS18C,ATP5PF,MRPL52,THG1L,HSD17B10,MRPS18B |
| 1.076e-09 | -20.65 | MRPL41 (mitochondrial ribosomal protein L41) | protein interactions | 64975 | 199 | 96 | 19454 | 5460 |
FAHD1,GATD3,PHB1,HNRNPL,DDRGK1,MRPL9,MTRF1,MRPS26,MRPL18,RHOG,HINT2,HSPD1,PREPL,IMMP2L,SOX2,E2F4,PDHA1,MRPL13,RPS9,CCDC90B,MTG1,TACO1,ESR2,RPL10,RPL19,RPL35,MRPL23,MRPL16,PMPCA,MYC,MTG2,AUH,RIT1,HTRA2,PSKH1,MRPL34,EXD2,NGRN,MRPL57,UFL1,HSCB,HNRNPA0,MRPL12,FAM3C,MRPS18A,COX4I1,COQ8A,MRPS9,SSBP1,MRPL24,SURF6,MALSU1,CDK9,CGAS,MRPL50,CAND1,FZR1,SPPL3,GRSF1,TMEM70,SNRNP70,CHCHD1,MRPL52,FASTKD5,MRPL22,TRIM63,METTL15,AURKAIP1,APOBEC3D,MRPL47,TP53,MRPL11,MRPL49,MRPL51,GFM2,MRPS28,MRPL53,VIRMA,TUFM,NONO,UBE2H,UHMK1,RC3H2,GFM1,MRPL20,MRPL40,NPM3,MRPL17,SMYD3,RBMS2,CFTR,MRPL10,PLP2,MTRES1,HEXIM1,MRPS34 |
| 1.078e-09 | -20.65 | regulation of macromolecule metabolic process | biological process | GO:0060255 | 6536 | 2104 | 18204 | 5365 |
BCL2A1,EIF4E3,SIN3A,LYAR,ELK1,ZNF592,RMI2,RMND1,POU5F1,MIR197,H3C1,MIR33B,MIR593,MIR210,POLR3F,RGCC,TIA1,MYBL2,POGK,RTN4,MIR548C,ZNF280B,ILDR1,ABCC2,MIR651,MIR519D,RBFOX3,MIR30B,MTG2,INHA,MSX2,MIR375,LILRA2,IL12B,RNF14,UBE3A,MIR185,PCBP4,POLR3B,MIR190A,STOML2,FOXP1,UBB,CAMLG,MIR107,ZFP64,MIR1-2,SERPINA1,RSAD2,USP2,COPS7A,ROPN1B,CBX3,MIR885,HSPD1,JUN,PNP,MORC2,CXXC1,SERPINA5,EMX2,ZFP1,FLOT1,MIR449A,MTA3,TSPAN15,TIRAP,MIR573,BST2,PKIB,MAF1,BCL2L1,DEDD,DERL1,BAD,PPP1R8,GSK3A,RAMP3,KPNA6,MIR643,H2AC4,MLLT11,MIR206,ODAM,SNX12,AATF,MSN,CRKL,DIRAS2,TRIM24,SKP1,PLAA,PHF21A,CTDSP1,CDK12,ARRDC3,BOK,OVOL1,PIK3R3,WDR77,RFC3,EP300,GPX1,LSM14B,CCNI,TMEM106A,ANXA7,CTSK,BACH1,CRTAP,MIR136,AKAP17A,UBE2V2,CDC7,GMNN,ZMYND11,LMNA,ZNF862,MIR9-3,DRD3,SELENOS,TANK,KHDC1,MIR92B,H2AC6,MIR99A,GABARAP,PRMT5,MIRLET7I,MECP2,MIR181C,TICAM1,SMAD9,CELF6,EXOSC3,MIR542,MOG,EDC3,TAL2,MIR29A,BMPR2,AFAP1L2,UTP15,INSM2,PQBP1,ITM2B,IRF1,NBN,TCEAL7,ACTR2,METTL14,RGP1,CTNNBIP1,TFIP11,NTRK2,CCT5,MIR551A,LMO3,IFI16,TAB2,IFNG,DTL,ZBTB5,STX5,TENT2,BIRC5,LGR4,MIR135B,OAZ3,PRKRA,MEF2A,SUMO2,PPID,ANGPT1,ZNF609,MIR34C,CDK20,SRC,SRGN,MTMR2,NRDE2,PTGES3,ZNF22,HNRNPK,NOVA1,TRIM21,ATF4,HEXIM1,HINT2,FAM168A,HNRNPF,RPAP2,FOS,PSPC1,CHI3L1,PRSS37,IRF2BPL,HLF,SUPT3H,PLP1,MIR937,P3H1,NFKB1,WBP1L,ZKSCAN1,LRIF1,ARG2,TESK1,HP1BP3,TICAM2,MIR222,CCNF,TRAF6,POU3F4,MIR802,MIR1180,NUDT12,MIR181D,PLAGL1,RNF40,MIR378A,TRIB1,CCL19,HOXD12,DUSP22,CSRNP1,MIR24-1,SMAD3,SCML2,ELF5,SELENOK,TMIGD3,IRF2BP1,TRIM62,KMT5B,EIF4A3,CCN3,HNRNPD,WNT2,TAF9,RHBDD3,KLF10,PCGF3,MIR924,MIR599,RALB,SETD5,MIR205,STAP1,MIR653,FCGR2B,ZNF32,ELP3,ATF3,USP8,RC3H2,SMG5,PFDN6,TRIM11,ACHE,SP4,MSTN,ZCCHC17,CAV3,BEND5,MEF2C,CBFB,HSP90AB1,CD28,TAX1BP1,VGLL4,FKBP1B,COPS4,WWP1,SNX3,TAF2,IFT57,CNKSR3,RUNX1,ZMPSTE24,ZMYM2,GFI1,PKIG,IFIH1,MIR208A,EGR2,ARL6IP5,PPP1R2,RPS27L,ARB2A,LILRB4,ZBTB42,AP2A1,TRIM26,HBEGF,S100A11,ZGLP1,HNRNPA1,MIR216B,WWP2,THOC2,GLO1,G3BP1,SPON1,TDRD7,PRDX3,APOBEC3G,MIR556,IER3,FRMD8,CREB1,MOV10,APLN,KLF9,SAP30BP,INPP5K,HTR2A,GATAD1,MIR190B,PSRC1,CD83,SASH3,H2AC13,KDM4B,MAGED2,CDK5R1,HSP90AA1,TGIF2,SMAD5,SOCS4,MIR708,MACROH2A1,RIT2,MMD,MAD2L1,USP14,ATP2B4,PFDN2,ZNF250,TRAF3IP3,PRKCB,CTBP1,SHC1,ZC3H14,ZNF174,PAGR1,BAZ1B,MIR20A,HBP1,CCL21,CIRBP,TADA3,NFE2,MAFG,CDK7,CSTB,ATP1B1,METAP1,PAK6,MIR144,TGFB2,CHP1,CRYBA1,ACTA2,HNRNPH2,RBM7,SVIP,SRPK2,NOTCH2,DBNDD1,CRIP1,RASL11A,MXD1,ZBTB38,SPRED2,MIR612,SEC22B,PCNA,RING1,HSBP1,ABHD14B,PXYLP1,SOX2,PTPN22,PDE8A,NFKBIB,TRIM37,USP13,RAP2B,IRF2,MIR940,GREM1,ADTRP,MTDH,TPPP,CCNQ,SNX33,PIWIL2,CDH13,CNOT7,MIR934,GAPDH,MYRF,TGFB1I1,SLC6A4,CLN8,POLR2L,LSM6,RAD21,IER2,IL7,MIR1262,ITK,EZH1,RFXAP,FBXO22,FZD6,ESR2,MIR711,JUP,GPNMB,RNF187,DCP2,RAP2A,RNF20,ZBTB6,TSPO,BTG2,RPL23,SFRP4,CSNK1A1,CCNA2,PTGER4,MIR626,MIDEAS,SP1,TENT5D,SPPL3,IDO1,TAF7,DIPK2A,PFDN1,IL13,MIR609,ZNF671,FHIT,MIR34A,MIR216A,IL21,CLEC7A,ZNF451,MITF,VPS72,MIR155HG,SCAMP5,VGLL2,PIWIL4,ACSS2,PTPRQ,HELT,FGFR1,ATXN1L,TRIM27,TFPT,NONO,CDK6,FOXI3,HUWE1,PTPN11,HDAC11,CKS1B,ENC1,JPH4,SPHK2,PSMD10,CXCL10,TNFRSF14,OGG1,MIR424,H2AX,SPINDOC,FBXW11,RAG1,PSME1,LDB1,XAF1,TFDP2,MTRES1,DIS3L,MIR581,RHOH,MIR1277,ACOT8,MIR657,PSMD14,MIRLET7C,CGGBP1,ROCK2,MIR567,YAF2,H2AZ1,ADIPOQ,LBH,FGF17,TRIM6,EEF2,RPS3,FOXP4,H1-1,ETF1,CBX5,TRAF2,NMBR,ZNF770,INO80C,EPHA2,CXXC5,CORO1C,MIR495,YTHDF1,BATF,AGER,MIR23A,MIR361,ZNF304,CAB39,S100A10,LARP4B,TXNIP,WNT10B,MIR577,PAX6,RIGI,GFPT1,SMYD3,PRKAG1,MIR454,MIR887,TP53INP2,BABAM1,OPTN,MIR383,ZBTB16,MIR148A,ZNF24,HDAC3,ATG7,IFNK,SMARCD3,MIR648,MIR96,ZNF507,TNIK,UBE2S,EHD4,AQP11,SFN,DNAJB6,LCP2,NACC2,MMP14,MCM6,UBE2K,ZNF513,MACIR,MAGEC2,GNRH1,CHMP1A,PADI2,PTP4A3,BAHD1,ID4,AHCYL1,ZNF581,TP53INP1,EIF4E,ZBTB2,MIR1224,CD274,FOXP3,ACTL6A,PPP1R12A,PPP2CB,KLHL25,SMARCE1,TENT4A,CLIP3,LMNB1,E2F4,SPRY1,HAX1,SNTA1,NRP1,MIR187,PCSK9,GNB3,FGF1,MIR125A,ACP5,PHC1,TAF11,TCEAL1,MIR10B,SMU1,PARL,ATF1,DIO2,RGMA,PSMA3,MIR450B,PRKCE,PID1,PFDN4,RPL13A,MED13L,XBP1,MIR492,SOD1,AR,MIR130A,PAK2,CYTL1,MIRLET7B,IL2,CAAP1,PAIP2,HIRA,TSC22D3,CCND1,SIRT7,MIR331,TCF23,SPRED1,BRD9,PPP1R11,NFKBIA,SAP30,CLK4,MIR345,ZNF688,MIR877,TEF,VDR,BAK1,SIAH2,TGFB3,AIFM1,VSTM2A,WNT7A,MIR374A,CEBPE,ITGA2,SERTAD2,RPL26,CCT7,FUBP3,ACO1,DUSP26,RPS4X,PPM1B,NUDT16,PRELID1,MTPN,FGF23,EIF3E,NSMCE3,ZNF704,SATB1,TIMP1,VEGFA,CTSA,IL23A,CLK1,MTA2,PRKACB,YWHAZ,CCL1,OSM,MIR301B,KLF1,PIK3R2,MIR944,CAMK1,BEX3,CAPN2,FZD4,KRBOX4,SOX14,DEK,TCIM,APEX1,NTF4,ZC4H2,PIK3CA,CD47,IL17F,TAF10,TAF1D,MIR15A,PHAX,SUPT4H1,ROCK1,ASB11,KLF3,CSH1,RB1CC1,CCDC85B,SERPINI1,H1-3,RNF41,CD40LG,PDE4B,TFEB,MIR140,MIR939,THY1,CD58,PDE2A,CIART,RBM42,EIF5B,ARL2BP,POU1F1,DNAJC1,DUSP6,CCL2,CHCHD2,CLEC9A,PHF23,PSMC5,SEMG2,NPPC,IGF2BP1,SERTAD3,TACO1,ZNF287,MYLIP,RARRES2,H2AC1,G6PD,MIR373,C1D,APOBEC3A,MIR632,MIR32,ZBTB39,CDK4,CYRIB,TBK1,XRCC5,VAMP3,DIRAS1,PIAS1,MIR101-1,APBB3,MIR363,VSIR,DCUN1D5,RASD1,CNOT6L,PSMC4,LAMP3,MED23,SERTAD1,MED9,MAGEA4,ZSCAN25,TRIM32,GPAM,UBE2L3,TRMT112,BOLL,HNRNPL,NLRP1,PITHD1,SYK,FGF16,HILPDA,MALSU1,TRIM5,MIR129-2,SELENOT,APOBEC3C,NOG,TESC,S100A8,PRR5L,EAF2,EWSR1,FBXW7,PRDX6,CPTP,GPBP1L1,CHID1,MIR101-2,EFNA5,ING2,DKK3,USP5,RUVBL2,LANCL2,MIR150,TADA1,SPIN3,SWAP70,MIR452,ILF2,IL4,MIR504,MIR662,THAP1,MDC1,MIR146A,NKRF,DGCR8,SCML1,FAM98A,MIR3173,TRIM68,TLR3,RPS14,DYRK2,AKAP12,CCL5,DMTF1,CST3,RORB,CRYAB,AGO1,NUPR1,SECISBP2L,DUSP19,FZR1,ZNF652,FLCN,MIR302B,MIR484,MIR761,RWDD3,EIF5A2,BCL10,MIR132,IL12A,MIF,HNF1B,PARD6A,STK3,ZNF518B,KLF12,MIR1225,SETD7,RNF34,IRF3,MAP3K12,HEY2,NR1I2,PELO,ING5,TRIM29,PRPF19,CDC5L,MIR339,FKBP1A,EIF4EBP2,CD200R1,MIR558,NUCKS1,CCR1,IRF8,SAP30L,SOX9,SART3,CBL,NDFIP1,GHRL,HNRNPA0,CSNK2A1,CPEB1,DHRS7B,PAEP,HOXC4,AZIN1,DLG3,RBM23,ZNF7,MIR489,SNAI2,KLHL15,MIR192,LRP3,DUSP3,MAP2K3,ZFAND2A,PARM1,PLD3,DPEP1,RPRD1B,OTUD7B,LSM2,SCAND1,MIR9-1,ZNF596,RERE,HOXB1,GLRX2,MIR367,RAB1B,SPOCK1,DKK1,MIR600,CHRAC1,RFC2,ADRB2,DDX4,SRSF7,LCORL,MBD3,HAND2,PRDM4,C9orf72,STAT6,RNF8,CCR7,ZBTB14,TRIM15,ZNF189,KPNA2,ZNF692,LGALS3,DET1,MIR335,MIR198,HEXB,MIR1249,DROSHA,ZNF326,ZNF526,MIR195,FAF1,PIWIL1,FOXJ3,HOMER3,MIR193B,MIR218-2,CDKN1B,TRIM52,TRA2A,PSME2,RBM3,UFL1,RBM15B,TP53,MIR583,MDM2,MIR188,SDCBP,HENMT1,NCBP2,DDX5,MIR1-1,PPIB,CSRNP3,HSPA8,INTS10,PTPN1,BAG2,ZNF473,TIMP4,ZNHIT3,IFI6,DLG4,CER1,JADE1,ZNF790,PAX9,MIR147A,MDFI,CDKN1A,MIR16-2,MIR105-1,MED4,TOP1,LSM14A,TENT5C,SUPT5H,MIR301A,NLRP2,TNFAIP1,ZNF365,ZNF655,RPL6,EID2,ILK,TMEM107,NLRP3,YWHAB,MIR502,H2AB1,MIR214,PPM1D,ZHX3,ZBED4,MIR552,PDCD1LG2,IRF4,FUT8,H1-5,CASC3,CLDN3,MUL1,CX3CL1,MIR1298,ANKRA2,NGRN,CAMK2N1,PHB1,RPA2,ING1,MIR624,FCGR2A,HEXIM2,CDK5,PLAC8,MIR615,CLDN4,DNAJC10,STUB1,FGF7,GTF2A2,DUSP10,MIR628,CCT8,PKIA,MIR649,KDM2A,MIR98,SERPINB9,IFI27,MED29,PC,FOXD3,TCF21,DXO,IREB2,LIG3,SRSF10,MIR129-1,RBBP9,CD36,BAP1,PMAIP1,UBE2B,CREBL2,TSPAN17,RHOBTB3,NGDN,SYNCRIP,MIR330,EMP2,SMURF1,DNM2,NOS1AP,MOB3C,CKS2,ECD,RPS2,MIR21,WDR82,ELP6,ANAPC2,CPNE1,FGR,RNASEL,LDB2,YWHAG,THRAP3,ZNF267,BTG1,GTF2F1,MIR633,RFX5,CSK,ERP29,DMAP1,ENO1,AURKAIP1,LDLR,HAS3,JUNB,OTX2,MIR186,TRIM34,PRL,VEGFC,TRAF7,PPARA,PELI1,RXRG,IFNGR1,EEF1A1,NEUROD2,ZNF263,PPP4C,MIR10A,LRP6,CAND1,USP3,STAT1,JAK2,MCPH1,PTEN,LMO2,FBXL19,MIR500A,MORF4L1,MED31,ABCE1,RAB27A,CD34,SMCHD1,DEFB114,CRY1,DVL2,LACC1,RLN2,EIF2AK2,CD14,GRIA1,LMO4,MIR377,CREBZF,TNFSF13,RIOK2,NCOA5,UBE2N,SLC8A1,CARTPT,RRN3,MIR497,PSMC3,MIR155,ATP5IF1,MIR221,SS18,KARS1,PACSIN3,NAA16,EIF3D,PDCD10,MAGOH,MIR384,DR1,SNX5,CYFIP2,KLK5,COPS7B,H2AC7,TSNAX,MIR1227,HYAL2,SHLD1,CTNNB1,SLC1A1,SP2,MIR938,SERPIND1,TNFSF15,NOP53,MIR578,UBE2V1,EID2B,MIR1271,INO80E,SMAD4,LSM4,RNF128,SMARCB1,IVNS1ABP,BMPR1A,NFE2L2,DNAJB4,SOX3,MPV17L2,PRMT6,SRSF4,UBASH3B,TFE3,SEMA7A,DRAP1,MIR549A,TRIM3,BRMS1,MIR100,GTF2IRD1,MIR625,EIF4EBP3,MIR153-1,EIF2B5,EIF3K,RFXANK,MIR618,MIR563,CCDC3,ZNF319,NTRK3,CIPC,MYT1L,TLR8,MIR296,MED17,MIR7-3,MIR873,DYNLL1,MIR34B,HOXB8,STK16,SMARCA5,EIF1B,ZNF740,SERPINH1,PIWIL3,FAM162A,MIR765,TNFSF12,POLR2G,COMMD6,LEP,SQSTM1,CD200,MIR601,MCM3,MIR148B,TCOF1,PHB2,ZNF175,PML,HCLS1,DISC1,BMPR1B,TFCP2,PABPC1,MIR141,CRADD,MIR491,SNAI3,TERT,EIF2S1,FKTN,NDP,ZBTB25,CAMK2N2,GADD45A,FXR2,GSKIP,CD2AP,LAMTOR1,CD38,NEK2,TLR5,SFTPD,H2AZ2,CRTC2,MAGEB10,PCBD1,NR2F6,TFRC,ELOC,SERPINB1,MIR920,RAP1A,PNRC1,TUSC2,OTULIN,MED30,MINAR1,MACROH2A2,CLU,MIR23B,STK38,PKNOX1,RPS7,NKX3-1,NFKBIL1,MTG1,MEAF6,RBFOX2,TAB1,TNKS,SOCS3,RBBP8,IFNB1,CAV1,MEPCE,PPP1CB,SUPT7L,AGAP2,RAB1A,PIM2,CDKN2D,ODC1,SLC38A3,BRCA1,ALKBH5,BUD31,MIR31,SERPINB6,SMAD2,MIR342,ZNF397,IRF9,RBM22,PSEN1,TNKS2,MTM1,CD4,MIR324,ZNF687,SNRNP70,ZHX1,IDE,APOBEC3F,UBE2I,SSBP2,LRRC14,PHF13,HCRT,DLX1,GPSM3,ITM2A,CASK,MIR106B,HSPB1,MIR490,MARS1,MIR142,DAPK1,CDC20,MIR553,MIR126,MYC,ZER1,MIR184,SNIP1,CDK1,SSBP1,ATP6AP2,MIR194-1,RPS6KA4,OSR2,DDT,APOBEC3D,MIR105-2,PDCD5,TNFSF8,CTDSP2,MED21,EED,NFIL3,MIR557,CHRM5,XPO5,ZBTB26,MIR1260B,ZSCAN1,ACTN4,NLRP6,IRF7,MIR425,CCT2,MIR200C,SMAD1,RNF126,HNRNPC,SETD3,TWIST2,DIRAS3,OAS1,CDCA7L,SUMO1,COPS5,LTA,FOSL2,ORC5,AIP,MTF1,MIR656,TRIM22,HSPE1,PYM1,PICALM,LITAF,CSTA,PPP1R3C,IL1A,DPY30,KRAS,IL2RG,IRF6,NCK1,TF,FGF10,DYRK1A,TM4SF20,WASL,GCLC,ZBTB18,MIR147B,TNFSF18,CREBBP,PROX1,KLK3,MIR152,ZNF177,MKKS,EGR1,MIR422A,IL34,IKBKB,EPO,ZNF664,SERPINA3,MIR28,AP1AR,NR4A2,MNAT1,MIR554,CHRNA7,UPF3B,IL3,EZH2,EIF4H,NCSTN,MIRLET7G,NFYB,YTHDF2,ZNHIT1,PGR,FAXDC2,PRKCQ,SLA2,MIR106A,SESN2,MIR193A,COP1,F11R,UFD1,HECTD1,GABARAPL2,MIR30A,PAQR3,CCDC22,EMX1,PPARG,DESI1,CTSC,FKBP8,SVBP,CXCL8,MIR133B,CCNY,ATG101,UBE2D3,UBP1,MIR770,ITGA6,FGF22,SIX5,ADORA3,ADORA1,PSENEN,P2RY1,SRSF1,MIR340,NKAP,EYA3,DDIT3,POLE3,DNAJC2,MIR586,MIR590,TOMM70,SMG9,USP16,APOBEC3B,RFC4,HSP90B1,DCUN1D1,ZNF593,INPPL1,ADNP,STRADB,CGAS,DAP,ZBTB45,TRA2B,BHLHA9,NFE2L1,ACVR1,RAD23B,AZIN2,EIF4E2,H1-6,BRD3,PRKCA,PLSCR1,BCL7C,F2,CCR2,POMT2,IL10,MIR640,FERD3L,MIR611,PTGFR,STN1,SRSF2,RAF1,ARMCX3,POLDIP3,CRLF3,RBBP7,MIR505,NAA15,MIR636,MAP3K11,DDRGK1,LY96,PPP1R1B,MSX1,MIR145,ZSCAN5A,CX3CR1,RFC5,CDKN2C,NKX6-2,TRAF1,TAGLN3,SSBP4,LBX1,RGS2,VPS28,DFFA,HMGB1,BCL7B,PYCARD,HRAS,GTPBP1,GABPA,HNRNPH3,BCCIP,MIR875,FOXS1,NMI,ZBTB33,ZNF576,MIR423,CLEC6A,MIR204,IKZF2,MAD2L2,SSBP3,GTF2A1,MED27,CD80,ANXA4,TAPBP,UCN,GABPB1,RPL10,MIR580,MCL1,METTL18,SMG8,PPP2R5A,E2F6,ADM2,MLLT6,MIR196B,MIRLET7D,PLCB1,TLR9,TNFRSF1B,ORMDL1,KCNIP3,FABP4,PPP1R10,DNAJC3,IFNA2,DNAJB2,MEF2B,CDC73,CDKN3,FCER1G,DDX1,KPNA1,ELF1,NKX3-2,G3BP2,ACVR1C,MIR223,SOX21,CD86,PYDC2,MMP9,PAIP1,LSM5,GNAQ,IFNA10,MOB3B,IL6,EFCAB7,TOM1L1,AGPAT1,USP38,MIR379,BAX,TRAF3IP2,ERRFI1,MATR3,HMX1,FOXN2,MPV17,UHMK1,COPS2,AKT2,PSMA6,DAPK3,MIR607,SLX1A,MIR589,SF3B4,CARHSP1,MIR130B,BVES,PRNP,NR1H2,TSG101,E4F1,MIR448,EGLN2,ZNF343,CDK5RAP3,KIT,ANP32B,FAS,MIR631,MIR320A,MET,TOLLIP,MIR1251,EIF4A2,TSPAN5,HNRNPAB,UBE2D1,MSH6,TGFBR2,PHF1,CALR,NSG1,MIR639,SKIC8,MIR675,GRSF1,CNOT2,WTAP,ENY2,APH1A,HMX2,IGF1,MIR604,PTRH2,DKC1,CCND3,TOX,MXI1,MT3,CREB3L4,INPP5E,NEUROD6,TXN,MAX,GSTP1,RBBP4,TNFAIP3,GH1,ZNF787,IL1B,AKT1,MIR569,DYRK1B,FAM107A,PPP3CA,CLP1,ELAVL4,MIR182,MIR211,MIR595,EIF4B,EXOSC8,AGR2,TLR6,SLCO3A1,MTERF2,RADX,IFNA13,MIR532,BCL9,MIR298,MIR455,MIR194-2,MIR137,IL15,MIR769,TLR1,CCAR1,MIR874,NF2,CEP85,SLC38A2,MIR652,MIR30E,FOXP2,MAGED4B,PSMD1,MIR922,NR0B1,SETD4,CUL3,MIR24-2,PIK3R1,RAN,NR2E1,TRUB1,MIR493,CCNB1,CRYM,ISX,NIBAN2,H2AJ,MIR218-1,TCP1,ELK4,CBX7,SPOPL,IFT52,MIR143,ETV6,MAGOHB,CAMP,NEO1,STAU1,PDCD4,CACUL1,MIR139,SERPINB11,WRAP53,BZW2,UQCC2,ELK3,IL18,MIR572,GTF2H2,MIR891B,FASLG,HNRNPA2B1,PIK3CG,EID1,WBP2,MAPKAPK5,NUP62,ZNF805,MIR7-1,MRTO4,H2AC25,MAP2K6,NHERF1,ZNF575,MIR16-1,DRD1,PIH1D1,DCUN1D3,CYP1B1,RPS13,MIR183,TLR2,GTDC1,HNRNPDL,CCNH,MRPL13,MRPL12,VIP,STAT5A,VRTN,RNF26,RNF10,AKAP8L,FAM161A,PTHLH,ATRAID,XPO1,TCEA1,CD2,NIF3L1,SPTBN1,DUSP1,BIRC2,YES1,LACRT,EGLN3,PRKAB1,HR,ASB1,TNRC6C,TMBIM6,CD40,ACVR1B,MED10,NR1I3,PSMC1,MIR592,MED22,CCAR2,CREB3,STK11,ALKBH4,MIR208B,INTS12,HDAC6,SGF29,MIR616,MAGEB1,FOXA3,NME2,KANSL3,FURIN,MIR760,ZBTB17,MAVS,TYROBP,MIR661,MIR876,FASTKD5,TOX4,RPS9,H1-10,NPTN,SERPINB10,TAF5L,MYD88,SPOP,HSPA5,SOCS5,IL20RB,BEND6,HTRA2,OPHN1,TULP3,CD81,NLRP9,ARPP19,IGFBP3,ZNF436,CD46,MIR149,MIR942,ZNF821,PELP1,MIR7-2,MIR200A,EPHA4,MIR605,DEFB124,MOSPD1,ZNF322,EFNA3,LRRTM3,CDC42,PPIA,RTRAF,SFRP1,MAGEH1,IGF1R,RBM12,TIMP3,RCHY1,CSNK1E,FERMT2,LILRB1,TPD52L1,CCL3,YWHAH,ID1,SRSF12,BARX2,RFX4,CSF2,STOX2,BTN2A2,GTF2F2,IL6ST,KDM1A,ZBED1,MIR29C,TLR7,TSN,BUD23,EDF1,IL5,RGMB,ANKRD49,MIR488,FCGR1A,PPP1CC,HDAC5,MAP2K1,MIR511,HGS,PRMT2,STPG4,TOB2,MIR936,STAT2,TMEM168,MIR429,MIR551B,RGN,SUB1,EXOSC4,IL1R2,CNOT6,SF3B5,IGBP1,DLG1,MIR215,BANF1,DNAJB9,IKZF5,DICER1,FIS1,TOPORS,ZCCHC7,OSBP,MIR597,MIR370,RLIM,NEDD8,MIR346,MIR449B,TRIM8,TLE1,RAB29,LTB,RABL3,MIR25,SPP1,DHX9,MIR30D,MIR517B,MSL2,ZNF345,HCFC2,MIR1226,BHLHE40,ZNF501,THAP7,ISG15,UAP1,TRIM44,RBCK1,LUM,MIR638,ZNF668,HINT1,C1QTNF1,HMCES,RNF139,TCEA2,GTF2I,LHX2,EIF2B2,PRIM2,IFRD2,B2M,RPS26,PSMB9,RHOG,CHMP5,SUFU,SUV39H1,MLF2,IMPACT,NQO1,HELLS,PLGRKT,KLHL22,EPCAM,SGTA,APOBEC3H,MIR503,MIR212,MLF1,MAEL,STK4,CIAO1,MIR671,TNFSF10,ACTL6B,OAZ1,PCGF6,MCM4,ASCC1,ZC3H7A,SOD2,NEK7,LEPR,ZNF362,SOST,EPOP,RAP2C,CIAO3,GHR,TRIP4,CRABP2,PCGF2,MGMT,MIR26B,SAP18,ZNF574,ITGAV,MIR99B,CNOT8,TLR4,APLNR,ARF4,TGIF2LX,KLF4,ZBED3,SDR16C5,CDK9,RBM5,DRGX,NDN,NFYA,RIOX2,RB1,CITED1,RNF141,TYMS,NAB1,MIR338,PHF12,PAIP2B,CEBPG,RBM38,CNTN1,MIR764,MIR17,GJA1,NEUROG2,CTSD,TBC1D16,AIF1,FOXC2,NAB2,XCL1,RBPJ,SF3B1,BRMS1L,SHMT1,TNF,MIR9-2,FGF3,TWSG1,ACTB,HMGA1,EDA2R,PDE12,RUVBL1,MIR191,CDK8,SH3BGRL,BCL6,CTDSPL2,PFDN5,HFE,SSU72,HMG20A,TOP2B,ORMDL3,PSMD3,MZB1,IL1RAP,LURAP1,ZNF511,TCF19,OAZ2,ITGB8,HINFP,MIR1296,FBP1,MED11,TBC1D24,EMILIN1,ELAVL2 |
| 1.106e-09 | -20.62 | CDC73 (cell division cycle 73) | protein interactions | 79577 | 377 | 160 | 19454 | 5460 |
RRAGA,UFL1,PITHD1,EEF1G,RAB30,HSPA8,HADHA,EP300,RAB5A,NUP50,SNRPA,IMPACT,RAB40AL,RCCD1,PFDN4,RPS5,HSP90AA1,PRSS1,PFDN6,H1-1,CCT2,YWHAZ,BRCA1,RNF40,BTF3,TTC33,SNRPB,CPSF2,MYC,GRB10,SFN,PSMB6,ESR2,DES,TAGLN2,ATP5F1B,GTF2F1,CPSF1,ARF1,RAN,POLR2C,RPN1,ACTN4,TUBA1A,SOX2,EEF2,SUPT5H,RPS27A,DMPK,ANP32B,SAR1B,SSRP1,G3BP1,KRAS,HNRNPF,PCNA,PICK1,RUVBL2,PDIA6,HSPD1,FBXO3,CCT8,YWHAB,HSPB1,DDX23,SKIC8,FKBP4,XPO1,DDRGK1,CTNNB1,PRDX1,PFDN5,RAB5C,CNTROB,LANCL1,HSP90AB1,RPS10,RAB1B,EIF2S1,SNRPA1,TCP1,RPL7,RFX5,WDR82,RPLP0,RARS1,ACACA,JUP,RPA2,HSP90B1,CPSF4,UBA52,TOMM20,HSPA5,HMGB1,ELOF1,TCEA1,RPA3,ZBTB38,UBE2H,TXNIP,TRIM23,RC3H2,CFL1,ATP5F1A,RPS17,AR,CEP70,PPP1CC,RAB2A,CIAO1,PTPN11,UQCRQ,UBB,CSTF3,RPL22,VIRMA,DDAH2,LDHA,MSN,ALB,RPS3,CCNF,ENO1,ZNF330,POLR2G,NUPR1,TFRC,TFCP2,CBX3,EEF1A1,CCT5,RPSA,RNF20,ARF4,MEPCE,H3C1,HNRNPK,CSE1L,FAF1,RAB1A,CNN3,USP15,GPRASP2,HM13,SUV39H1,GAPDH,CALR,KARS1,CDK9,MYL12A,CDC5L,G6PD,FZR1,PLG,ALCAM,CAND1,TOP1,MIF,TES |
| 1.119e-09 | -20.61 | SPTBN1 (spectrin beta, non-erythrocytic 1) | protein interactions | 6711 | 357 | 153 | 19454 | 5460 |
RHOU,BAP1,SOD1,RPA3,GRIA2,SIRT7,NF2,PIK3R2,FBXW7,PIAS1,HSPA5,SPTBN1,CAPN1,CRAT,CDC42,CDK7,CFTR,PTP4A2,RPA2,METTL14,HSP90B1,STUB1,CCNF,CTTN,EIF4A3,CTNNA1,UBASH3B,TRIM24,PTEN,COPE,KCTD9,DAPK1,RHOJ,SMURF1,DYRK1A,VIRMA,RAB2A,USP14,PPP1CC,DNAJC5,RC3H2,PKNOX1,SMAD2,MAPRE1,UBE2H,NEDD8,CAPZA1,UBL4A,TP53,ACTR1A,TFCP2,TFRC,CAPZA2,DISC1,RNF8,NUPR1,HRAS,SMAD3,ADD1,MYBL2,TES,RAC2,ARF6,CPNE1,EIF2B2,STX6,CDK9,CAV1,CDC5L,DPP4,COPS5,CSNK2A1,HDAC6,LAMP3,TUBG1,SMAD4,PSMD7,SHC1,H2AC4,RPS2,DDX39B,HSPA8,UFL1,CYFIP2,NOP53,CMTM6,STX7,RRAGA,WDR77,RND2,PPP1CB,STXBP1,PPT1,PCLAF,PIH1D1,CMTR1,AP2M1,STAT1,ACTB,FBXO22,APEX1,MYC,ACO2,RAB11A,CUL3,SFN,BTF3,MCM3,LAMTOR1,YWHAZ,PSMD14,RHOB,BRCA1,HSP90AA1,CDKL2,VMP1,MEF2C,RINT1,EWSR1,PLCB1,KRAS,TRIM37,FLOT1,RAF1,SNAPIN,SOX2,MSX2,KIF2A,SPG21,EZH2,CHMP4C,RND3,TNIK,RAB35,GJA1,RHOH,SPTAN1,SUMO2,DIRAS3,STK3,LAMP2,RAB5C,YWHAG,YWHAH,RHOG,AGR2,PPM1B,CBL,SMAD9,YWHAB,MAGOH,HSPB1,BCL2L1 |
| 1.130e-09 | -20.60 | COPS3 (COP9 signalosome subunit 3) | protein interactions | 8533 | 226 | 106 | 19454 | 5460 |
FEM1B,NT5C2,CTNNB1,DCAF4L2,DCAF11,IKBKB,AGR2,MAP1LC3A,COPS2,WDR6,FBXO32,NABP1,HSP90AB1,COPS7B,SOX2,TNPO2,TULP3,RAF1,MOB3C,TUBB4B,EWSR1,PCNA,AHCYL1,COPS4,KRAS,RUVBL1,MYC,COPS7A,HNRNPC,CUL2,CUL3,COP1,HSP90AA1,DCAF4,MCPH1,IRF2,FBXL14,NFKBIA,APEX1,ESR2,FBXO22,DYNLL1,DET1,TOR1AIP2,FBXO42,FRS3,ADNP,APPBP2,HSPA8,DDIT3,HADHA,DR1,LCA5,FBXW4,SPECC1L,SKP1,SRSF2,UFL1,EEF1G,COPS5,CSNK2A1,ELOC,AP5S1,USP15,CRBN,BECN1,SRP14,LRRC14,DCUN1D1,PHYH,INSIG2,TP53,KLHL15,MAP1B,PPP1R12A,APBB3,SOCS2,ARF4,HUWE1,NEDD8,FBXO7,ATP5F1A,KPNA6,MLF1,SMARCA5,DTL,STK11,NCKIPSD,BICD2,SYT2,PHAX,CSNK2B,CCNF,TUBA1B,VIRMA,CEBPE,TPT1,UBE2M,LMNA,RPA2,HBB,BAP1,RPA3,HSPA5,KDM1A,FBXW7 |
| 1.134e-09 | -20.60 | establishment of localization | biological process | GO:0051234 | 3887 | 1298 | 18204 | 5365 |
EHD4,AQP11,SFN,SLC39A9,SYT4,RHBG,DSN1,HM13,GRIA2,FABP4,PPP1R10,TIMM17A,HDAC3,MLLT6,FAM53C,PLCB1,ATG7,LEPROTL1,KCNIP3,OCIAD2,MCL1,KCNMB2,CHMP2B,TAPBP,PNPLA8,OPTN,VPS18,PRKAG1,TRAPPC3L,SLC35C1,SCAMP2,PAX6,SMYD3,XPOT,TXNIP,EDNRA,PEX5L,SAR1B,SLC35E1,CLIP3,CALHM5,LMNB1,SNAP29,SPRY1,OXSR1,MIA2,MIR130B,BVES,CDC42SE1,EMC10,AKT2,VPS26B,TMED1,MPV17,SLC37A4,CA2,IL6,TOM1L1,LAMP2,AHCYL1,GP9,TRAF3IP2,EIF4E,RTP4,BAX,UQCRC1,GNAO1,DDX39B,CHMP1A,ACAA2,CETN2,CEP19,GLTP,GPM6B,LRRTM1,THOC6,ACVR1C,G3BP2,BBS5,BORCS6,DNAJC27,MACIR,RAB23,IMMP2L,SLC2A8,SLC7A1,ZDHHC14,ARL11,KPNA1,FCER1G,SLC6A12,TGFBR2,CCND1,LAT2,LMBRD1,SOD1,SYNRG,BUB3,MET,CPE,KCNK17,FHIP1B,XBP1,CYB5R4,KIT,SLCO2B1,SLCO1B3,CPLX2,PRKCE,SLC25A10,SYVN1,ATP5MC1,LASP1,KCNS1,TSG101,KCNK13,TFG,PIP5K1A,PCSK9,PLA2G5,KCNH8,SLC25A26,TMED4,AGR2,SLCO3A1,SLC35F1,SLC25A31,TSPAN10,FKRP,VPS39,SLC6A1,ARFGAP1,WNT7A,PPP3CA,SLC45A3,CEBPE,KCND2,AKT1,AIFM1,RHAG,VDR,MAP1B,BAK1,RHCE,TNFAIP3,RAB3D,DYNC1I2,ATP5PD,OXTR,MT3,SLC18B1,RFTN2,ENY2,UCP2,NFKBIA,ROMO1,CALR,NSG1,ATP6V1G2,ABCB1,SNX18,STIM1,NIBAN2,STX17,FZD4,SLC52A3,TIMM21,BICD2,CAMK1,BET1L,NDUFB8,GORASP2,CRYM,CCNB1,CUL3,AGK,SRP72,ATP6V1E2,PIK3R2,MTX2,WDR19,CCDC47,RAN,PIK3R1,SLC6A6,ACAP2,TPD52,YWHAZ,NDUFS6,CPLX1,KCND3,MIR301B,IPCEF1,TERB2,BORCS7,SLC38A2,VEGFA,CTSA,SNX24,FXYD6,PPM1K,SEC62,NDUFB4,EMC8,FABP5,PRELID1,AP2S1,ABCG2,HIKESHI,FASLG,PARP11,HNRNPA2B1,NECTIN2,TRAPPC2L,SLC6A11,PIK3CG,PMP2,STX18,NDUFB10,CHTOP,LRP10,NDE1,GTF2H2,OLFM2,SURF4,GPIHBP1,NEO1,STAU1,STX10,COMMD9,P2RY12,THOC1,ZFAND2B,SYT2,MAGOHB,PHAX,SLC13A5,PIK3CA,CD47,ATP5PB,ARFGAP3,IFT52,PAFAH1B1,CACNB2,NLGN1,NUP107,RAB22A,CDC23,NDUFS2,VAMP3,PICK1,TRMT10B,VPS54,YIPF5,DPP4,PPIF,FEZ1,VIP,STAT5A,NPTX1,BPGM,HBE1,STX6,SNAP23,GLRB,USE1,SLC12A2,FKBP4,RAB5A,SLC16A10,CHRM3,CACNB4,DRD1,ATP5F1D,TIMM8B,SYNGR3,SYP,CLEC9A,CLCN6,SLC16A4,NGB,IGF2BP1,NHERF1,CBLN4,WBP2,TRAM1L1,TUBB,ARL6,EXOC2,EHD3,NUP62,SLC35B3,LIN7B,S100A8,TESC,HDAC6,SGF29,ZDHHC17,STX16,ZC3H11A,SELENOT,STX11,TMED9,SYK,RAB14,ARFGEF1,NUF2,SCG5,DERL2,VMP1,NUP37,ASIC1,SLC23A2,YES1,RAB33B,LACRT,STAR,TIMM13,RHOBTB1,LAMP3,NPC2,YKT6,UBAP1,SLC2A1,NAIF1,SPTBN1,SCYL2,ATRAID,XPO1,SCN3B,CCDC186,SLC6A8,ATP5PO,FXN,AQP3,CD81,SLC25A51,ATP2C1,HSPA5,OPHN1,KLHL3,IFT22,CYTH1,NDUFC2,MYD88,AP2M1,RUVBL2,COG1,SLC25A17,VTI1B,CLIC2,KCNAB1,TYROBP,MFSD5,CPTP,FURIN,CSNK1G3,NDUFB7,UNC119B,ATP6V1D,STX8,CSF2,CFL1,STK3,SLC48A1,RNASEK,OPRM1,RAB18,ATP5F1A,HNF1B,NXT1,CCL3,NDUFS8,YWHAH,RAB9A,SLC6A7,LILRB1,SCG2,RTRAF,ARFIP1,IGF1R,SLC6A2,MTMR6,GOSR2,CSNK1E,IFT172,FTH1,ICAM3,SOCS2,CDC42,KCNB1,TUSC3,CCL5,FCHSD2,KCNC1,ZDHHC15,ABCB9,RAB4A,HBB,COX4I1,FIS1,NAPA,LRRC8C,POLA2,CBLN1,BECN1,TRAPPC3,SLC25A14,KIF1C,DLG1,RAB3A,EMC1,RAB13,GHRL,VTA1,NDFIP1,CBL,BAG3,CCR5,ERO1A,OLR1,CCR1,MRC1,RAB28,SLC19A3,KCNIP2,HGS,IRF8,SYNGR1,JAKMIP1,WDR11,SLC66A2,SKA3,VIPAS39,RABL2B,FCGR1A,FKBP1A,MIR29C,CSE1L,SLC38A9,COPZ2,NR1I2,OS9,CYTH2,CCR7,THOC3,ADRB2,ELMO2,SRSF7,TVP23B,SLC31A1,PPY,C9orf72,TOMM22,RAB3B,GAS8,ATP6V1C1,CMTM6,SLC7A8,RABL3,NAPG,KXD1,VAMP8,RAB1B,DHX9,GABRG2,GJB1,RAB29,SLC2A3,GJB2,JAGN1,FBLN5,EMC4,KCNMB1,CD209,LCA5,SLC35F2,ALB,PPFIA2,ATP5MG,LRP3,OSBP,HRH2,LRWD1,SYNGR2,ZFAND2A,CHMP4C,SCFD1,SLC15A2,FCMR,SLC16A1,SV2B,RBM15B,BET1,SGTA,CDKN1B,CDO1,CD3G,S100A6,MLC1,SLC25A12,APOO,TNFAIP8L3,CHMP5,FYTTD1,HOMER3,MAPRE1,B2M,CYB5R1,SLC22A6,IPO8,SAMM50,KPNA2,GABRA2,SNX2,SLC51A,SLC35D1,APOC2,GPM6A,CDAN1,CYP27B1,RAB3C,TMEM147,TMED7,CLCA1,RPAIN,TMEM14A,ZBED3,RPS15,TLR4,DLG4,ARF4,NUP42,SEC14L1,TMEM165,TMEM38B,CRABP2,RAB30,ITGAV,ANO3,ACKR3,TRAM1,ARHGAP1,SLC15A1,HSPA8,LARGE1,SNX20,GHR,SYNJ2BP,NDUFV2,RHCG,SKA1,KIF3B,EHD1,CNP,SSR1,GABRA1,LEPR,SLC25A39,NCBP2,SSR2,MDM2,SDCBP,PPFIA3,TP53,MAP1S,SPCS3,SLC7A9,UQCRH,STK4,STARD5,SLC25A27,AIF1,H1-5,CASC3,ORAI3,ARF6,MAPKAPK3,YWHAB,MIR17,CKLF,RP2,GJA1,SEC61A1,EXOC3,TRAPPC6A,RAB31,RB1,NUP35,LRRC8D,CITED1,SLC25A5,SLC22A12,GPR89A,RSRC1,TBC1D10C,FOLR1,RAB37,TOMM20,CDKN1A,HINFP,RNF5,PITPNA,ARHGAP12,TBC1D24,SSR3,SMDT1,SNX22,SLC22A17,MYO1B,RANGRF,SEC22A,FGF7,ELMO1,NSFL1C,CDK5,KCNMA1,GOLPH3L,RHOU,RAB11B,ARL4D,CTDSPL2,HFE,CLDN4,ATP1A1,SEC13,AVPR1B,SLC25A4,ANP32A,ERLEC1,ING1,VAPB,GRPEL2,RANBP6,MUL1,XCL1,PPT1,COX4I2,ATP6V0E1,SLC35A2,AQP4,CPNE1,COX7A1,TRAPPC1,SFT2D2,CD9,CACNG3,EMP2,ILDR1,SMURF1,ABCC2,DNM2,SLCO1A2,SLC38A7,UBE2B,RHOBTB3,GUK1,TSPAN17,EXOC1,CD36,TPT1,SNAPIN,SLC32A1,PMAIP1,KCNH1,SYN3,IREB2,NDUFS3,LGI3,SRSF10,GJA10,TSPAN18,CHMP2A,TIMM29,VAV2,SLC25A42,BCL2A1,TRAPPC6B,AQP2,LRRC8B,GRM1,SERPINA5,MAP4,SLC1A3,SNAP91,UPRT,FLOT1,VPS33A,NCKIPSD,TNPO2,PRL,KCNA2,TRPC1,VDAC1,GRIK1,USP6NL,AP1G2,CPLX3,HSPD1,LDLR,AP1S2,CNNM4,ERP29,SEC22C,NDUFB6,COX6B1,UBB,CAMLG,DYNC1I1,YWHAG,PEA15,KCNF1,MYO6,COPE,UBE3A,MX2,DUOXA2,FGR,ATP5IF1,NUP153,NUP50,ARRDC3,SLC7A4,ATG4C,CARTPT,SLC8A1,CCHCR1,SNX12,GRIA1,ENKD1,ADRB3,TIMM8A,SEC61B,CD14,GSK3A,RAMP3,TOMM40L,FAM91A1,TEX261,KPNA6,HBM,RAB27A,TUBA1A,ABCE1,SSX2IP,SLC4A8,BCAP29,CYB561D2,DERL1,BAD,GRID1,MCPH1,STXBP1,APOC4,DDX39A,BCL2L1,ATP8A1,MIS12,SLC41A3,STX7,NCALD,VLDLR,VPS26A,GABARAP,FTHL17,UBXN6,DRD3,SELENOS,PEX26,FAM53B,CALHM2,LMNA,P2RY4,TBC1D4,PHETA2,SLC1A2,HYAL2,CTNNB1,VPS26C,SLC1A1,KDELR2,RALA,IFT25,PDCD10,VDAC2,RAB5C,AP1M1,MAGOH,CYB5A,SNX5,BOK,TMC7,NPC1L1,CAMK2G,PACSIN3,VAMP1,NTRK2,AP3S2,BORCS5,STARD4,TOMM7,ACTR2,TMED3,RGP1,BLOC1S5,SNX11,SHOC2,SNX1,SNCG,ALYREF,EHBP1,LYSET,DNAJC5,SLC30A5,SLC25A32,NIPA2,TRIM3,TOMM6,TRAPPC4,KDELR1,SLC38A1,SEC61A2,SLC41A1,LYPLA1,SYS1,BNIP3L,MIR29A,FBXO7,AKR1C1,SNX17,COX17,EMC9,SIGMAR1,MECP2,NDC80,MAIP1,SFXN1,GOLGA7,SLC25A23,ATP5MC3,ZMAT3,PLCB2,PHB2,LEP,RAB40AL,SQSTM1,TM9SF4,NME1,SLC25A21,EXT1,KCNJ11,MGARP,PPID,DAG1,CALY,SH3BP4,SLC25A46,ADRA1A,SRC,ARL4A,RAB8B,TMCC1,SFTPA1,HBA1,TOM1,GOLGA5,CHAMP1,SEC23A,STX5,DYNLL1,SLC39A3,SNX10,SERINC3,CCL19,SFTPD,C2CD2L,RAB35,GRM2,JPT2,ESYT1,UMPS,RAB19,SLC25A20,CD2AP,LAMTOR1,DNLZ,NDP,TICAM2,TSPO2,KCNJ3,NLGN2,VPS16,FXR2,SSNA1,LAMP5,TERT,KCNJ8,NDUFB5,TESK1,FGF13,SRI,UBXN2B,HCLS1,PRSS12,SLC11A2,MRPL18,SRPRA,SLC25A44,NECAP1,SYBU,PML,FCGR2B,NDUFA5,ACTR1A,FCHO2,TMEM167B,GRPEL1,ZDHHC4,SLC25A3,RINT1,KCNG3,CLU,MACROH2A2,UBL4A,RALB,RILPL2,TMEM108,PLSCR4,RAP1A,EIF4A3,CYBRD1,CRHBP,SRP14,TUSC2,NXT2,TFRC,SELENOK,GIT2,SEC63,CLTRN,LMBR1L,ATG16L1,SLC7A11,PLP2,ATG4A,CD63,KCNJ10,VAMP5,CLDN1,ATP1A3,UBE2I,PSEN1,ARL6IP5,EGR2,MTM1,GJC1,ATG9A,LILRB4,SLC19A2,AP2A1,ZMPSTE24,TNPO3,GABRB2,SLC38A3,ALKBH5,WWP1,TRAM2,SNX3,SMAD2,IFT57,NDUFA4,AGAP2,NME4,RAB1A,SLC25A45,BLOC1S3,FKBP1B,PLEKHF2,CAV3,LCA5L,FTL,MCOLN1,ATP6V1A,CDR2L,STARD3NL,CAV1,ACHE,SLC20A1,MPC1,SMG5,NECAP2,TNKS,SYNDIG1,SFXN2,BTF3,HSP90AA1,NDUFA12,CHRM5,SNAP25,MAGED2,GDI2,MTCH2,CNIH4,TRAPPC13,REP15,PSRC1,KCNJ2,APLN,ATP6AP2,HTR2A,IER3,TUBA1B,CREB1,ATP1B3,TOMM40,SNCB,G6PC3,HSPB1,SLC35A1,GOSR1,ZFAND6,SLC25A1,SLU7,FAF2,SLC20A2,ATP6V0B,SLC43A2,PEG10,ZNF207,SLC25A28,CASK,COX7B,DNAJC19,HNRNPA1,PREPL,WWP2,SEC61G,THOC2,TMEM50B,GLRA1,PMPCA,RIMS3,CLBA1,TST,ATP1B1,SLC35F6,ATP1A2,NDUFA2,PICALM,CCL21,SLC30A7,ARHGAP25,AIP,ATP5PF,AP5M1,ARL5B,PLA2G12A,COX8A,PRKCB,CTBP1,AFTPH,CHGA,LRP12,FOSL2,SLC25A24,RNF126,CRHR1,FABP12,RAP1B,MFSD14B,COPS5,EDEM1,RER1,MAD2L1,ATP2B4,CHRM1,HPS6,TTC8,XPO5,CAV2,MACROH2A1,SLC35A5,ACTN4,SVOP,MARCHF3,SNX33,FOLR2,TIMM10,AP5S1,RBP2,VPS4B,ZDHHC24,TOM1L2,TMEM115,WASL,GCLC,TRIM37,SELENOM,NDUFA1,SLC5A6,PEX13,HSBP1,FABP7,ATP6V1G1,EIF2D,SPC24,ATP5F1B,SEC22B,FGF10,EMC2,CPT1B,TF,CPT2,RIMS4,STBD1,KLHL12,DPY30,SLC6A3,SLC7A14,PLSCR3,CHP1,FCN2,CRYBA1,PPARG,KCNK10,ARCN1,ANKRD50,DESI1,CYP7A1,LIN7C,RACGAP1,LIPA,RPL23,RAB39B,YIPF4,OSTM1,YIF1A,CCDC22,GLE1,SPCS2,RABIF,RAP2A,UFD1,TSPO,TMED5,GABARAPL2,SLC35E3,RHOJ,GOLGA7B,CETN3,STX12,CALHM3,SESN2,MREG,FBXO22,CEP41,SLC25A11,CHRNA7,OSBPL8,CHRNB2,UPF3B,ATP5F1E,RAB32,PTGDS,SLC6A4,SRP54,CLN8,AP1AR,TRAK2,CNTN2,MKKS,AGAP1,COX5A,CHCHD4,SLC17A5,CCL8,NETO1,TOMM70,SLC4A10,DDIT3,TRIM27,LRRC8A,AZGP1,GHITM,COMT,P2RY1,PLPP4,SRSF1,TMEM87A,ICA1,SCAMP5,CHMP1B,SGIP1,ADORA1,CLEC7A,CYGB,SCN1B,SLC39A7,VPS4A,ARHGAP21,TAF7,SKA2,CXCL8,BLOC1S2,ABCC5,SRPRB,GNPTG,TMEM30A,NOP9,SVBP,CLIC4,BCS1L,ARF1,SLC39A13,EXOC8,CCR2,SLC29A1,EXOC5,SLC35B4,PLSCR1,ORAI2,WDR83OS,RAB9B,SLC22A8,TBC1D17,DDR1,KCNQ5,SCN2B,NEFL,CFTR,LMAN1,TMEM184B,TBC1D5,TRAPPC10,PLEKHJ1,SLC35E4,SPCS1,FBXW11,ASIC2,CTTN,TRIM23,STRADB,ANKH,PEX3,ATAD1,TBC1D13,SPRN,INPPL1,PLEKHA8,KCNA3,VAMP2,TIMM23,ATG3,BORCS8,CIDEB,CYC1,JPH4,HSP90B1,GLRA2,S100A10,PREB,TRIM46,RHOB,PLEKHF1,AGER,MFSD3,STXBP6,HRAS,PYCARD,PITPNB,CORO1C,GABRB3,HMGB1,RAB6A,STX1A,CXCR1,CDC42SE2,TMEM184C,EMC6,VPS28,RAB2A,MRGPRX2,HRH3,TMEM144,RBP5,TMEM106B,RAB11A,SNX14,RAB6B,VAMP7,COMMD3,POLDIP3,APPBP2,TMEM50A,CACNB3,SLC39A10,RAF1,ARMCX3 |
| 1.144e-09 | -20.59 | SENP2 (SUMO specific peptidase 2) | protein interactions | 59343 | 165 | 83 | 19454 | 5460 |
TMPO,MYL12A,LMAN1,NUP35,FZR1,DNAJC1,SUMO3,RHOH,SUMO2,PRNP,HSD17B11,GJA1,RAC2,RAB35,PTPN1,RPRM,KPNA1,RHOG,ESYT1,SLC25A46,SMN1,MDC1,NUP107,HNRNPK,TRIM63,KPNA2,RUVBL2,S100B,TMT1A,CCT8,SDR16C5,RPN1,STIM1,EZH2,PNMA2,RAB4A,NUP153,SERPINA3,EEF1A1,DNAJC25,TPD52,TOP3B,ACTB,SYNE4,TUBB,RETREG3,SEC61B,APOC4,TUBA1B,ENO1,RPS5,FIS1,CCT2,LMNB1,AR,RBM15B,MYC,STK38L,CIAO1,RAB11A,STX7,PXMP2,STK38,HSPA8,DERL1,RAB9A,DVL2,PML,APOC2,MYL6,LMNA,HBB,SSR1,SNAI2,H2AC1,CDC42,SEC62,FUNDC1,OTULINL,ST7,SUMO1,AGTRAP,UBA52 |
| 1.145e-09 | -20.59 | response to oxygen levels | biological process | GO:0070482 | 331 | 149 | 18204 | 5365 |
NPPC,NGB,FOS,PML,HSP90B1,GAD2,CDKN1A,FOSL2,LTA,MAP1LC3A,KCNJ8,TERT,GUCY1B1,ADO,PRKCE,EGLN2,BAD,MIR448,CYB5R4,CD38,MIR214,MIR17,CPEB1,TERC,MIR20A,ERO1A,TLR2,FAS,CBL,NDP,HP1BP3,CLDN3,DPP4,BECN1,SLC29A1,PICK1,CYP1A1,EP300,STC1,UCP2,DIO3,POLB,TNF,SLC2A1,ADIPOQ,SMAD3,TGFB2,IL1A,PARP2,SLC1A1,AGTRAP,KCNMB1,MT3,EGLN3,TFRC,OXTR,BIRC2,LMNA,HILPDA,STUB1,SOX2,NOP53,WDR83,CXCL12,ATP6V1G1,AKT1,AIFM1,KCND2,KCNMA1,TGFB3,NDNF,NKX3-1,CXCR4,DDIT4,FUNDC1,CREBBP,AGER,SMAD4,ITGA2,RAD21,NR4A2,CAV1,ATP6V1A,SLC6A4,NFE2L2,EPO,EGR1,EDNRA,MECP2,TMEM199,PMAIP1,MIR210,VEGFA,BNIP3L,CAV3,MSTN,CHRNB2,CHRNA7,ATG7,CDKN1B,SUV39H1,RGCC,ALKBH5,AQP3,PGK1,FZD4,CAPN2,PPARG,SCFD1,CCNA2,TXNRD2,MIR146A,SLC2A8,MIR106B,F7,MIR223,MDM2,LPAR1,ERCC3,NDUFS2,MMP14,TP53,CYGB,MYC,MIR126,SFRP1,MIR34A,SOD2,ACAA2,CRYAB,MIEF1,MGARP,KCNJ11,COMT,FAM162A,SRC,ADORA1,CIAO3,SOD3,PHB2,PSEN2,CLCA1,ATF4,TM9SF4,MIR140,HMOX2,PPARA,LEP,VEGFC |
| 1.147e-09 | -20.59 | LAMTOR5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5) | protein interactions | 10542 | 147 | 76 | 19454 | 5460 |
NR1H2,LAMTOR3,TCAP,AKR1C2,ATP6AP2,BORCS7,RABIF,LRIF1,TRMT6,MCPH1,ALB,LAMTOR1,MAF1,SNX5,CDC16,STK38L,GORASP2,CEP70,STK38,SLC31A1,SKP1,HSPA5,DNLZ,PIP4P1,MT2A,SLC18B1,MTHFD2L,RAB9A,HMCES,BORCS5,ACAA2,PTP4A2,GIT2,BORCS8,EIF4B,RRAGA,ATP6V1C1,BORCS6,ANKRD46,PEG10,NKIRAS2,UBP1,HRAS,SIN3A,LDLR,RAC2,DSTN,SMAD4,RPL23,TAF9,LAMTOR2,HEBP2,KXD1,MOV10,GAPDH,STK4,SLC38A9,TRIM63,VRK1,KRAS,ZBTB16,RRAGB,ZNF592,TOP2B,MKLN1,BLOC1S2,TFCP2,SERPINA1,BIRC5,TBC1D4,GFM2,STX12,TP53,SNAPIN,PPARA,EEF1A1 |
| 1.153e-09 | -20.58 | CCT3 (chaperonin containing TCP1 subunit 3) | protein interactions | 7203 | 568 | 225 | 19454 | 5460 |
MOB3C,HDAC11,TUBB4B,PLS3,ISG15,TUBA1A,SOX2,ERRFI1,KRAS,PSMA2,ACTR1B,CDK5,CCT8,RBM3,CTTNBP2,AGR2,DCAF5,DDRGK1,ACTR3B,WWP2,PFDN5,MAPK4,CCT7,DYNC1I2,TCP1,SUMO2,EED,WDR82,PIH1D1,PACRG,PPT1,FBXO42,PAFAH1B1,EEF1G,STAU1,HNRNPA0,UFL1,DDX5,P4HA2,HDAC5,HSPA8,DDX39B,COP1,ICAM1,PSMD14,CCT2,BTF3,KLHDC8A,LDHB,PSMA4,MYC,ESR2,CYP27A1,DCAF12L2,TFCP2,ACTR1A,TP53,STRADB,MEPCE,PSMA5,KDM4B,POC1B,METTL18,MAP1B,ZDHHC15,TUBG1,B9D1,CD81,CSNK2A1,CDC5L,TMPO,SPPL3,FZR1,ITK,ACACA,UBE2M,HEXIM1,SAMM50,RPRD1B,TRIM68,WRAP53,RPA2,CFTR,BCL6,MARS1,WDR55,HDAC3,HCFC2,BAP1,UBE2H,ZBTB38,ATP1A1,DTL,RC3H2,RAP2C,ETFBKMT,AKT1,CARS1,SLC25A1,CDC20,SUCLG2,MAP3K3,BUB3,KCTD9,MOB4,PSMA6,UQCRC2,CREB1,POLR2C,GNB1L,NME1,NGB,RPN1,EZH2,WDR37,B3GNT2,RAF1,SAR1B,PCGF6,RAD21,ETFA,G3BP1,ZC3H7A,DCAF11,AHSA1,SKIC8,CETN2,EGLN3,SRSF10,BUD31,MAP1LC3A,IGBP1,PPP2CB,PHB1,SLC25A3,PPARG,VAV2,LNX2,WDR77,ACTL6A,PAFAH1B2,GPC1,PPP2R2C,UCHL3,PSMA3,FBXW4,THOC3,RIT1,ILK,PFDN4,PFDN2,DCAF4,BRCA1,CUL3,KLHDC8B,GNB1,ACTB,LGALS3,PRDX2,ARF1,RNF181,VAC14,PPP4C,ACTR2,MMACHC,MAP1LC3B,CCT5,HSPE1,DNAAF10,HUWE1,PC,HAPSTR1,GLUL,FAF1,FGR,DNAJC7,SUV39H1,HDAC6,FNDC11,CDK9,EIF2B2,METTL6,EEF1AKMT3,ARL10,EFNA3,HNRNPH3,PDCL,METTL14,HSP90B1,STOM,GRM2,CCND1,ATG16L1,WDR5B,WDR83,FBXW7,IRF7,GTF2I,SQSTM1,PRPF4,SIRT7,INPPL1,RPA3,CDC73,STK24,IVNS1ABP,CIAO1,CTSD,PDCD5,VIRMA,SH3BP4,YES1,ARMC6,LDHA,NDN,ABHD17A,UBASH3B,MSN,PTEN,ZBTB18,GANAB,METAP2,TUBA1B,SMAP2,CCNF |
| 1.178e-09 | -20.56 | MTIF3 (mitochondrial translational initiation factor 3) | protein interactions | 219402 | 295 | 131 | 19454 | 5460 |
ORMDL3,GRSF1,ZDHHC15,ADGRE2,TRMT5,TMEM11,TMEM42,LDLR,MRPS9,COQ8A,RPRM,SYNCRIP,MGME1,COX4I1,DBT,ATP5PD,STX6,MRPL24,MRPS23,MRPL50,CXCL9,PPIF,BCS1L,ATP5PB,NDUFA2,INSIG2,SELENOK,MRPL47,STARD4,MRPL49,MRPL51,NDUFS3,MRFAP1,UNC50,MRPS18B,SEMG2,THG1L,MRPL52,ATP5PF,CLEC7A,MRPS18C,FASTKD5,MRPL22,PDE12,MRPS33,HNRNPK,FBXO7,TUFM,NDUFAF2,PYCR2,PEA15,MRPS16,MRPS28,CYBC1,ACAT1,CDIPT,MRPL53,PLP1,VKORC1L1,SERTM1,MGST3,MRPS21,CD47,MRPL10,NDUFAB1,MRPS34,QRSL1,CZIB,TWNK,TMEM254,DLAT,TMEM243,ORMDL1,CRYZ,MRPL20,MRPL17,PDHB,NME4,MRPL41,MRPL40,MRPL9,NDUFV2,CLPX,MRPS35,STOML2,MRPS26,BCL2L1,MRPL18,TMEM97,NDUFS8,PNPLA8,HNRNPL,SNX2,TMEM176A,HSDL2,ETFB,NDUFA12,NDUFS6,PDHA1,HINT2,TMEM147,MRPS11,MRPS17,HNRNPDL,ETFA,KGD4,ATP5F1D,MRPL16,VEZT,PYCR1,HNRNPAB,PLN,MRPS25,CGRRF1,MRPL13,TACO1,DLST,NDUFAF4,THBD,ATP5F1B,MRPL23,SIAH1,MRPL12,CTXN3,NDUFA5,MRPS18A,ATP5IF1,HADHA,JAGN1,MRPS7,NDUFS2 |
| 1.239e-09 | -20.51 | ubiquitin protein ligase binding | molecular function | GO:0031625 | 303 | 140 | 18094 | 5411 |
SMAD2,PRR5L,TUBA1B,HM13,DLG3,NFKBIA,CACUL1,GPR37,CD40,ISG15,MAGEC2,CCT2,BRCA1,RPL23,RPA2,CDKN1B,LTBR,RRAGA,GABARAP,TMBIM6,FBXW7,HSP90AB1,USP13,MAP1LC3B,UBB,PSMA3,TRAF2,FZD6,UBE2W,CAMLG,ACVR1B,CALR,TNFRSF1B,UBE2A,UBA52,JUN,SUMO1,UQCRC1,EGR2,POU5F1,DERL1,RNF34,ABCB1,BECN1,SMG5,RPS27A,ERLIN1,MDM2,SMAD3,DET1,RIGI,PIAS1,NAE1,NDUFS2,NEDD8,TP53,HAPSTR1,PRKACB,PRDX6,CUL2,TRAF1,SMAD5,PACRG,CTNNB1,BAG2,JKAMP,UBE2L3,CUL3,RNF8,FATE1,CACYBP,UBE2D1,CKB,TRIM37,EIF4E2,YWHAZ,RNF40,ANKRA2,RTN4,PSMD1,HDAC6,PML,UBE2B,SLC25A5,CXCR4,TUBB,HSP90AA1,PTPN22,CLU,MAP1LC3A,UBE2N,SPOP,SMAD1,SHPRH,STX8,TSG101,WRAP53,UBASH3B,XRCC5,STUB1,CDKN1A,BOK,NFE2L2,CASC3,FZD4,HSPA8,HSPD1,PAX6,SPOPL,GABARAPL1,FAF2,UBE2D3,JAK1,RHOBTB3,USP2,TCP1,TANK,WBP1L,TXNIP,FBXO7,RALA,ANAPC2,TOLLIP,HSPA5,TRIB1,FAF1,DIO2,TNFRSF14,SUMO2,ERLIN2,GABARAPL2,RB1,RALB,RNF20,DBT,FHIT,BCL10,MUL1,UBE2K,SQSTM1 |
| 1.246e-09 | -20.50 | NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1) | protein interactions | 4719 | 329 | 143 | 19454 | 5460 |
SFXN1,CLPB,EMC2,DNAJC30,TOLLIP,FASTKD5,ATP5PB,FBP1,MRPL11,MTCH2,AURKAIP1,APOO,METTL15,NDUFS3,GFM2,SDHB,AIFM1,SSBP1,EHBP1,COX4I1,COMT,LDLR,RAC2,NDUFA1,PRNP,MIF,MYL12A,TMPO,MDM2,SLC25A12,GRSF1,DPP4,EMC4,LAMTOR2,ATP1B1,POR,ESYT1,CHCHD1,TMEM70,DNAJC4,RHOU,RPL27,PML,SIRT7,GFM1,RNF113A,TMEM126B,RPS15,KDM1A,PDHB,SLC25A51,CRYZ,CDC42,UQCRC1,NDUFAB1,CFTR,METTL2A,STOM,HSP90B1,MTRES1,CYC1,UQCRC2,RHOJ,UQCRQ,TECR,TNFAIP3,FGFR1OP2,SLC25A1,NDUFB10,HMOX2,TUFM,ATP1B3,ATP1A1,DNAJC19,UBE2H,NDUFB5,GPAA1,HSPD1,NDUFA4,HINT2,COX8A,KRAS,EMC8,VDAC1,IMMP2L,EZH2,PDHA1,NDUFS6,NDUFA12,STX12,OTULIN,PHB1,CORO1C,GATD3,ATP6V1A,RHOH,UQCRH,EGLN3,NDUFS8,RMND1,COX14,MTRF1,RAB5C,NDUFV2,RHOG,MRPS26,NGRN,BMPR1A,DDX39B,EXD2,HADHA,EMC1,NDUFS2,HSCB,PHB2,ARMCX2,TOMM22,RND2,TIMM29,ARMCX3,SLC25A3,NDUFA5,VDAC2,TACO1,CCDC90B,MTG1,MRPL13,ATP5F1B,ACTB,ACAP2,APEX1,PARL,COX6B1,AUH,MTG2,MYC,CUL3,PMPCA,TOMM40,PCCB,LMNB1,RHOB,HTRA2 |
| 1.279e-09 | -20.48 | COPS2 (COP9 signalosome subunit 2) | protein interactions | 9318 | 240 | 111 | 19454 | 5460 |
VIRMA,UBA3,PHAX,ING2,SYT2,PSMC5,GTF2H2,MACROH2A1,CCNF,TUBA1B,PSMA6,NCKIPSD,ANAPC4,STK11,DTL,NIF3L1,NR0B1,ATP5F1A,FBXO7,AR,KPNA6,CDC16,HSPA5,KDM1A,PFKFB2,NUCKS1,PPM1G,RPA3,BAP1,UBE2M,RPA2,LMNA,RNF103,SLAIN2,CDC5L,DCUN1D1,KPNA1,CRBN,CSNK2A1,COPS5,ERCC3,APBB3,SOCS2,SEPHS1,EIF3E,NEDD8,CTNNBL1,H3C1,THRAP3,MAP1B,KLHL24,PSMC3,ING1,WBP11,TP53,IP6K1,CAVIN2,DYNLL1,RBBP4,FBXO22,SNRNP40,FBXL14,CPSF1,NFKBIA,COP1,RIT1,SENP8,DCAF4,COPS7A,SYCE3,CREBBP,CUL3,PMPCA,CUL2,PSMC1,EEF1G,APPBP2,EP300,HADHA,FBXW4,MED23,DET1,FBXO42,EGLN3,HSP90AB1,COPS7B,COPS2,SOSTDC1,SIN3A,WDR6,MED4,DCAF11,FEM1B,NT5C2,DCAF4L2,RAB5C,COPS4,AHCYL1,RBBP7,KRAS,FBXO11,RHOBTB1,RPS23,IRF8,SKA3,TUBB4B,ANAPC13,JUN,TUBA1A,TULP3,VDR |
| 1.284e-09 | -20.47 | ERLIN2 (ER lipid raft associated 2) | protein interactions | 11160 | 221 | 104 | 19454 | 5460 |
OSBPL8,STYK1,DPP4,FAM20C,SLC25A46,EDEM1,ADIPOR2,GAPDH,TMPO,ZBTB2,PTPN1,ARL10,TFRC,FURIN,NUPR1,UBL4A,KBTBD4,CCDC47,MAP1LC3B,CSE1L,APH1A,SRPRB,PSEN1,FASTKD5,FAF1,RIC3,NRP1,UBE2H,RAB2A,SLC25A1,VAMP5,CCNB1,GORASP2,CTSB,RPGRIP1L,DUSP3,CCNF,TUBA1B,AMIGO1,CDK1,RPA2,HSP90B1,STOM,GRM2,KRT7,SCLT1,GABRA1,CFTR,NF2,TMUB1,HSPA5,RPA3,SYVN1,DERL1,RTN4,AGR2,RNF139,HAX1,RB1CC1,HSPB1,DDRGK1,TCP1,ERLIN1,STK3,PHB1,FBXO32,GATD3,HDAC11,TOP3B,B3GNT2,FAF2,TUBA1A,NCSTN,EEF2,VDAC1,FLOT1,CHST10,EWSR1,CCT2,SP1,GSTM5,UFD1,TUBB,TAX1BP1,FBXO22,MAD2L2,ESR2,LMBR1L,SEC61B,UBAC2,FKBP14,PGRMC1,BET1,TMUB2,EDEM3,UFL1,EMC1,RNF5,PSENEN,STAU1,ADRB2,TMEM106B,HSPA8,PMAIP1 |
| 1.287e-09 | -20.47 | ZNF746 (zinc finger protein 746) | protein interactions | 155061 | 315 | 138 | 19454 | 5460 |
UBE2E3,TEX19,IGF2BP1,AP2A1,ATP1A1,RPL7A,SLC25A1,TUFM,HMOX2,NONO,RPS17,ATP5F1A,RPL13A,SLC25A4,RPL10L,LDHA,FBLN5,UQCRC2,RPS12,MRPS28,PRKRA,HSP90B1,IDH2,MRPS34,CDK1,ACACA,CYC1,RPLP0,RPL26L1,NTPCR,RPL4,WDR3,PDHB,RPS15,MARS1,PGK1,RPL10A,OSBPL8,AKAP8L,RPS2,MOV10,RPS27L,RPS16,CAND1,SLC25A12,CDC5L,MRPS23,FAM118B,MYL12A,AIFM1,COQ8A,MRPS9,SRP14,SYNCRIP,PWP2,NDUFS3,SRP72,ILF2,RPSA,MRPL11,EGR2,WBP11,FARSA,NUP107,SMN1,EIF3E,MSH6,SLC25A11,SFXN1,DHX9,PC,RPL3,FTSJ3,H1-10,DNAJB6,ILK,H1-1,LDHB,MYC,MCM3,PCCB,RFC5,PRPF31,RPL35,ATP5F1B,RPL10,ESR2,NCKAP1,ELK3,RPS9,AP2M1,ZMYM2,ATP5PO,SLC25A3,NOTCH2,RPL27A,PHB2,PPP2R2C,UNC45A,PSMC1,XRCC5,RFC4,HADHA,RPL23,AHSA1,RPL6,PSMD3,EIF3D,TCP1,RPL7,LYAR,NOP58,HSP90AB1,DHX15,MRTO4,PHB1,SRSF1,RPL8,RPLP2,MAGED2,PNMA2,RPN1,RPS23,SART3,RPL18,RPS11,NAA15,EEF2,TRIM37,HNRNPF,PAX6,POLDIP3,MRPS17,RPL28,SLC25A5,RPS24,UBE3A,MYO1B |
| 1.297e-09 | -20.46 | extracellular exosome | cellular component | GO:0070062 | 2175 | 753 | 19108 | 5553 |
UPK1A,GCNT3,MIF,CCT7,FLRT2,BST2,HEXB,SHMT1,CEACAM5,MGAT4A,PRDX6,GNG12,PPP1CB,PRRC2A,ATP6V1C1,ATP1B1,PSMB1,RPSA,H2AC7,MIR1234,HINT1,TXNDC17,LAMP2,RNF11,FCN2,EHD1,CPNE2,HIRA,FBP2,CYBRD1,CCT2,RUSC2,SLC15A2,B4GAT1,RAB5A,CCT5,FKBP4,SOD3,SH3BP4,FAM168B,ADGRG1,NCSTN,VAMP5,FAH,LYPLA2,OGN,RHOJ,RPL37A,GNB3,DEFB1,PDIA3,BPIFB1,CD81,LUM,DPEP1,SERPINA3,PACSIN3,MIR29A,DNAJC3,PAFAH1B2,PYGM,ABCB1,PRELP,ACTR2,CDH13,GGCT,RPS26,GBE1,SLC12A2,PSME1,GSTM3,PBLD,ITGB5,AQP2,PTGDS,PSME2,HBA1,TFRC,STAMBP,ANXA4,IDE,GK2,MPST,ANGPTL2,GSTA1,RPL27,SRSF7,GSTO2,NAA16,SFRP1,GDPD3,BTG2,FGL2,ANGPT1,GAPDH,CPE,CCL28,OLA1,LGALS3,BPIFA2,FAM234A,THY1,RPS13,RAB11A,RUVBL1,MIR24-1,TUBB,FUT8,COMT,NPC2,EEF1A1,MIR619,PRNP,SRI,CAB39,PABPC1,THRAP3,NEDD8,TCP1,ZNHIT6,SERPINB6,EPS8,PDZK1IP1,LDHB,RAB3D,RAB6A,MIR17,CSK,STK26,SOD2,GNG2,ATP5F1A,PRDX2,RAB11B,SCPEP1,HNRNPA1,DUSP26,PSMA2,PCNA,S100A6,CD58,LAP3,HSPD1,GMPPA,RPS4X,HEBP2,GCA,PEBP1,ATP1B3,CSRP1,CRYAB,RPL26,SFN,PNP,CTNND1,MIR29C,TUFM,ARPC2,PAFAH1B1,TOR1B,RPL3,VAMP7,APEH,H2AC25,ARPC3,SLC16A1,TAGLN2,AIF1L,FABP5,PLCB1,GNAI2,CFAP20,PALS2,MIR146A,GSTP1,YWHAG,GSTA2,RAB29,C1GALT1C1,NCKAP1,TOR3A,RAP1B,ACP2,AK2,PSMB4,AKR1C1,USP14,PDCD10,MIR208A,GSTCD,ACAT1,GALNT4,ICAM3,SERPINB1,PITPNA,ACTR3B,MIR16-1,PRSS8,TUBB4B,TMED9,MIR423,UBE2D3,STOM,SNRPD2,TXN,ADSS2,GNAQ,SLC2A3,CDC42,RPS14,VAMP8,SNCG,PSMA6,SERPINI1,NME1,HUWE1,PPIB,MIR125A,SNX3,CYFIP2,RHOG,CACYBP,MBLAC2,NME2,RPS9,CKB,TF,VPS4B,PEBP4,MIR23A,KRT8,TNFSF13,TMBIM1,GSTK1,JCHAIN,GLO1,RHEB,PRKACB,STK11,CD248,RAB2A,SOD1,TMEM256,CHMP5,S100A11,TIMP1,WWP1,PPT1,GMDS,CNP,HBB,AASDHPPT,LILRB4,FTH1,FBP1,OXSR1,CD63,IRF6,CLIC4,ENO2,PRCP,SSBP1,GPX3,CDK1,MIR638,MTAP,RPS29,SVIP,RNASET2,GABRB2,NAA50,RAB22A,AHSA1,YWHAB,AKR7A2,EIF3E,AZGP1,LMAN1,AKR1B1,SLC25A3,VDAC1,GNPTG,PSMA1,CAMP,ALPL,RRAS2,WWP2,EIF4E,RHOB,FAM3C,MIR10B,SPP1,PLAA,CSE1L,MIR338,DDAH2,NECTIN2,CUL3,CALR,CMBL,RPLP0,PROM1,PPP2R1A,SEMA3C,FAS,SIT1,CHI3L1,MBD5,RAB4A,CAPZA1,MGAT1,AP1M1,ST13,BPGM,SNX18,MME,PI15,TOM1L2,CYB5R1,S100A8,PSMD3,EIF2S1,CXCL12,PPIA,TPT1,F2,PMP2,TOM1,RAC2,CTSC,RPL23A,AOX1,RPLP2,MIRLET7C,H2BC14,GOLGA7,STAU1,PSMB5,ZMPSTE24,DDT,FABP4,GNA11,H2AC13,RPS20,DNPH1,DDR1,LCP1,H3C1,FLOT1,GAL3ST4,EPCAM,PGAM1,TSG101,KRT7,TSPAN3,YWHAH,B4GALT3,RPS28,RNASE1,SNAP23,SH3BGRL,CAPZA2,ATP6AP2,CTNNB1,TXNRD1,RPL26L1,GLIPR2,HNRNPC,ESD,CSNK2B,MIR34A,PSMB9,AP2M1,PPFIA2,MDH1,HSPA8,ARHGAP1,GPX4,CD38,TTR,VPS4A,MYL6,LAMTOR3,MSN,CAPN2,RAB14,RPL28,DSTN,MIR21,GLOD4,CNTN1,STX7,CNDP2,PSMA5,CD9,UBXN6,HSP90B1,RPL10A,CD79B,FTL,H2AJ,GPC1,ATP5F1B,PHB1,LRRC57,SUB1,MIR193B,RETN,MYL12A,ARL6,CST3,EEF2,ANXA7,COTL1,TOMM70,DNAJC7,HNMT,CD46,HGS,B4GALT1,CYSTM1,MACROH2A2,EFNB1,PSMA3,RAB3B,PABPC1L,SMURF1,RPL35A,SPTBN1,PROS1,CD274,RPS16,H2AZ1,SDC4,MARS1,PRDX4,UBL3,PLA2G15,BLVRA,TNFSF10,GLRX,VMO1,GFUS,MIR143,ITM2B,NUDT5,CHP1,SAT2,TUBA1A,RAP1A,SYPL1,SERPINA1,PCBD1,PIP4K2C,XPNPEP1,SYNGR2,CYRIB,MIR1304,NHERF1,F9,JUP,FGR,SIAE,AHCYL1,WASL,CD59,RPS3,RPL23,REG1A,FOLR1,HSPB1,HP,ALCAM,GNA14,RPE,MIR223,CLU,HNRNPA2B1,ACTN4,SPR,ENPP4,GSTO1,RAP2C,CAND1,FURIN,ACTR1B,HSP90AB1,DDAH1,CD40,PGK1,DDX5,SDCBP,EHD4,HSPE1,GSTT1,TSPO,H2BC9,HSPA5,PSMB2,CFL1,PSMB3,RBP5,UBA52,IL18BP,PLSCR1,SLC38A1,SERPINC1,SLC22A6,H2AC1,TAX1BP3,GDI2,RAB1B,HTRA1,ARF6,MIR671,SLPI,ITGB8,RPL22,ACTB,PRSS23,SEMA5A,SERPINB9,MIR145,RP2,DNM2,MAT2B,KIF3B,MMP9,CD2AP,FSTL1,CRTC2,CRYL1,RAB13,SCAMP2,H2AX,ALDH1L1,RACGAP1,SEMG2,HEXA,GNG7,CPNE1,DICER1,FBLN5,ATP8A1,IDH2,UGDH,MACROH2A1,STXBP1,AGAP2,PSMA4,TPM3,P3H1,MGP,GNB4,CRABP2,S100A10,SLC25A1,VTA1,COL1A2,CTSD,RPL24,ALB,GPT,CDH11,PYGB,NAPG,RPL4,RPS2,REG1B,RAB19,ACO1,SRPRA,SERPIND1,RAB8B,TOLLIP,ABHD8,RAP2B,RPS27A,ST3GAL1,SLC22A8,YWHAZ,SQSTM1,EMILIN1,H2AC4,CD86,CLTRN,CCT8,MTMR2,PSMB6,UBB,CTSA,DPP4,TNIK,RUVBL2,ACTR1A,STK24,SEPTIN7,MIR342,NEU1,PLG,CRB3,GPRASP3,ICAM1,B2M,ATP6V1A,CHMP1B,SPTAN1,DNAJB9,RPL12,CHID1,CRYM,G6PD,UBE2V1,GFPT1,FAM20C,SLC2A1,TMEM59,PSMC5,MEST,ITGAV,SAMM50,CMPK1,CHMP1A,GNG5,CTDSP1,RALB,SELENOP,HSP90AA1,IDH1,H2AZ2,RPS11,GPM6A,PGM1,WASF3,NIBAN2,MYO6,DLG1,RHCG,GSTM2,F11R,PRKCA,GLUL,CD14,ARF4,PGA4,DAG1,MYO1B,RPL31,RAB1A,HSPA13,CAPN1,SLC35F6,CUTA,ANP32B,CFL2,GNPDA1,H2AC6,CAPG,UGP2,ACTA2,PRDX1,VPS28,TNFAIP3,MIR9-1,PDIA6,SLC22A12,MARCKSL1,WNT7A,ALYREF,GGH,CTSB,LYZ,YES1,GSTT2B,PPIC,UBE2V2,FASLG,ATP6V1D,MYL12B,BAX,CXCR4,NAPA,MIR15A,GNAI3,GRID1,TOM1L1,PDE8A,RARS1,HEBP1,LAMB2,MIR197,VWF,RAN,EEF1G,CD47,PADI2,ATP6V1G1,NUDT9,SLC1A1,GANAB,PSMD7,LAMTOR1,AKR1A1,SRC,LAT2,LDHA,CRYZ,DDX23,ALDH1A3,CHMP2B,ABHD14B,PLD3,KLK3,RPS5,MAN1A2,SEC13,MIRLET7B,ATP1A1,IL6ST,RAB27A,CA2,TAX1BP1,ENPEP,GHITM,SFT2D2,ENO1,CSTB,RAB5C,HNRNPL,SERPINA5,ARL15,RHOBTB3,HNRNPK,CHMP2A,RAB9A,PRKCB,CHCHD3,RAB35,UBE2N,SORD,ENDOD1,GPC4,ACSL4,GNB1,ARF1,RALA,PSMD12,DES,MIR30D,SLC20A2,LYPLA1,AMY2B,PDCD5 |
| 1.309e-09 | -20.45 | TFRC (transferrin receptor) | protein interactions | 7037 | 462 | 189 | 19454 | 5460 |
RAB35,LAPTM4A,RHOH,EXOC1,DDRGK1,TBC1D5,RAB5C,SYNJ2BP,LAMP2,HSPB1,CBL,AGR2,IKBKB,TMEM87A,KRAS,ISG15,DNAJC25,HGS,RND3,PDHA1,RAB4A,BST2,LMBR1L,ATP6AP2,ESR2,IREB2,ATP5F1B,STX16,MYC,SERPINH1,KCNA3,SLC38A1,LAMTOR1,RAB5A,EP300,HDAC5,HSPA8,ADRB2,STAU1,TRA2B,EMC1,RALYL,SEC62,BET1,MTMR6,TOMM22,EFHD1,RAC2,CD4,RNF128,STX6,LMAN1,SVIP,CD81,COPS5,DPP4,KARS1,TMOD2,CD247,ERO1A,RAB3B,TOLLIP,TP53,INSIG2,PREB,NUPR1,ARPC3,RELL2,TFRC,STX10,SGTA,B4GALT1,SEC61A1,RPGRIP1L,DNAJC5,GJB2,VAMP5,RAB2A,SLC25A1,CALU,SNX5,MARCHF3,HFE,RAB9A,BAP1,HSPA5,AIF1L,CDC42,SPTBN1,VIPAS39,FGFR1,RPA2,ATP6V1A,XPO5,GJA1,DIRAS3,SNX2,SPTAN1,ATG9A,AHSA1,RHOG,COX8A,ERP29,BAG2,TMT1A,SCYL2,FLOT1,G3BP1,LGR4,ERLIN2,ACTN4,ARFGAP1,CYB5B,STX12,CHMP4C,RPN1,VAMP2,VPS33A,SEC61B,RMDN3,RAB11A,VEZT,RIT1,NTRK3,SCFD1,MYO6,BRCA1,LMNB1,RHOB,SLC35F2,PMAIP1,RNF11,STX7,RND2,KLF3,VAPB,TES,SRPRA,HRAS,PTPN1,CAV1,MDM2,ARF6,SNAP91,HDAC6,LAMP3,POR,EMC2,IGF1R,STX8,PDE2A,ARF4,TF,HUWE1,MAP1LC3B,CCDC47,VAC14,GANAB,EIF4A3,SMAP2,SCAMP2,OPTN,CCNF,VAMP3,VIRMA,SH3BP4,RHOJ,SNX3,RAB14,TMOD3,MGST3,GMPS,RUNX1,NAPA,CDC73,AP2A1,SQSTM1,RHOU,RPA3,GABARAP,FBXW7,B2M,YKT6,ARHGAP1,ATG16L1,MET,METTL14,GRM2,LMNA |
| 1.321e-09 | -20.44 | defense response to virus | biological process | GO:0051607 | 275 | 128 | 18204 | 5365 |
IRF9,TRIM52,IFNK,TLR9,ATG7,IFIH1,PQBP1,EXOC1,MYD88,IRF1,APOBEC3F,RNASE1,IFI16,DHX16,OPRK1,TLR8,NDUFAF4,APOBEC3H,DNAJC3,IFNA2,NLRP9,TRIM26,TICAM1,RIGI,IFI27,TRIM11,IFNB1,TRIM15,CNOT7,MAVS,IL23A,POLR3F,PMAIP1,POLR3H,SAMHD1,BNIP3L,APOBEC3D,MIR26B,TRIM34,MOV10,LILRB1,TRIM35,ELMOD2,MX1,NT5C3A,IRF3,PHB2,ZNF175,IFI6,TRIM27,TRIM21,AKAP1,G3BP1,CXCL9,IL12B,MX2,IFNG,DDX1,SERINC3,RNASE6,TLR3,POLR3B,RNASEL,PRKRA,IL6,RSAD2,IL21,AZI2,RTP4,APOBEC3G,IFNA10,EXOSC4,TRIM22,APOBEC3A,STAT2,TLR2,EIF2AK2,TRAF6,BECN1,TBK1,UBE2N,PLSCR1,IRF7,TLR7,NLRP6,LSM14A,BCL2L1,CXCL10,DHX15,APOBEC3B,BST2,STAT1,PML,KCNJ8,MAP3K14,OAS1,CGAS,NLRP1,MBL2,ZMYND11,IRF2,TTC4,CD40,VAMP8,ISG15,DDIT4,IFNA13,UAP1,HCFC2,TRIM5,ISG20,TANK,APOBEC3C,PYCARD,TNF,UBE2W,ATG16L1,IFIT2,CLPB,HYAL2,NMBR,TRIM32,GPAM,PHB1,NCK1,TRIM8,TRIM6,PDE12 |
| 1.325e-09 | -20.44 | LARS1 (leucyl-tRNA synthetase 1) | protein interactions | 51520 | 352 | 151 | 19454 | 5460 |
MIR363,RIT1,BRCA1,MYO6,ATG3,ATG101,MIR98,MYC,CUL3,CUL2,MIRLET7D,MAD2L2,APEX1,PRDX2,PSMD4,SSH3,TUBB,DYNLL1,PSMD6,LMBR1L,RAN,EIF4B,RTF2,PIH1D1,EMC9,RNF7,PRDX3,ETF1,BET1,MIR106A,EMC1,STAU1,MCMBP,EEF1G,HSPA8,HDAC5,RPS28,RB1CC1,MIR1-1,MIR221,SKIC8,MIR31,AGR2,MIR29C,CTNNB1,GSTM3,WWP2,DHX15,HSP90AB1,RPS10,SUMO2,MIR9-1,RPL7,ATP6V1A,MIR214,MIR7-2,PHB1,GTPBP1,MOB3C,GLE1,SKA3,RAB4A,SOX2,FAF2,TRAF2,ISG15,PPP2R1A,EEF2,TOP3B,AP1M1,UBE2A,KRAS,VDAC1,MIR206,RUVBL2,HSPD1,PABPC1,CCT8,UBE2H,USP14,MAT2A,CARS1,CIAO1,GNAI2,VIRMA,NDN,KCTD9,TMOD3,CCNF,OPTN,PSPC1,RPS3,RPLP0,HEXIM1,RARS1,MIR21,MIR7-1,SDCBP,VPS4B,RPA2,METTL14,MIR1-2,CDC42,MIR34B,ATG16L1,SPTBN1,EEF1E1,MYL12B,CAPN1,ARHGAP1,MARS1,MIR29A,MIR107,FBXW7,MIRLET7I,RNF113A,DLAT,MIR34C,RPA3,SOD1,BAP1,MIR10B,SNAPC1,MIR205,MAP4,MIR34A,H2AC4,TPM3,KARS1,TMPO,G6PD,PLEKHF2,RPS16,MIRLET7G,MIR25,RPL12,MIR106B,SRP14,TAF2,GNAI3,MIR17,EEF1A1,MAP1LC3B,MIR15A,TP53,MIRLET7C,RPS13,ERO1A,MIR9-3,RAB1A,MIR200A |
| 1.352e-09 | -20.42 | PCDH7 (protocadherin 7) | protein interactions | 5099 | 276 | 124 | 19454 | 5460 |
DDX39A,CCT5,CAPZA2,TFRC,HSD17B10,CYBRD1,PC,DHX9,RPL23A,RPL3,CAPZA1,HNRNPK,HSPE1,LAMP3,CMSS1,CALR,DPP4,AKR1B1,RAC2,HRAS,SYNCRIP,CAV1,STX6,ARF6,RPL35A,CDC42,ARL15,MET,RPLP0,FGFR1,STOM,HSP90B1,LMNA,PRDX6,RNF113A,MTDH,PGK1,RHOU,DDX46,HSPA5,NONO,DNAJC5,CFL1,RAB2A,SLC25A1,ABCG2,MSN,GANAB,TUBA1B,CTTN,ENO1,RPS3,VIRMA,RHOJ,LDHA,PNP,RPS7,EEF2,PPP2R1A,MARCKSL1,RAF1,DTWD2,RND3,GDI2,NME1,TUBB4B,RPS24,PCNA,CCT8,PABPC1,HNRNPA2B1,SLC25A5,HSPD1,SAR1B,RPS27A,VDAC1,TNF,KRAS,HNRNPA1,YWHAG,PDIA3,LAMP2,PRDX1,FCGR1A,HNRNPD,FKBP4,KRT8,GJA1,PHB1,RPL9,RAB35,RPL8,ARL11,HSP90AB1,DIRAS3,RHOH,TCP1,EIF2S1,RND2,NOTCH2,MYL6,EIF4B,HSPA8,XRCC5,DDX39B,STX7,EEF1G,LDHB,RAB11A,SFN,MDH1,SP1,HSP90AA1,KLK5,YWHAZ,S100A11,RHOB,LAMTOR1,CCT2,CKB,RPL10,TUBB,PRDX2,TAGLN2 |
| 1.389e-09 | -20.39 | DHX9 (DExH-box helicase 9) | protein interactions | 1660 | 590 | 232 | 19454 | 5460 |
RPL31,ABCF1,PABPC1,EWSR1,RTCB,KRAS,HNRNPF,HNRNPDL,TOP3B,ISG15,SOX2,MSX2,SRSF1,EED,HNRNPL,LYAR,MACROD1,IFI16,RPL6,WWP2,PPIB,DDRGK1,CTNNB1,AGR2,DDX1,DRG1,SNRPA,RFC4,DDX39B,XRCC5,HDAC5,HSPA8,DDX5,RAB5A,EP300,HNRNPA0,EIF1B,UFL1,STAU1,MTF1,RPL27A,FBXO42,PPT1,PIH1D1,CMTR1,ATP5F1B,MATR3,RPL10,MYC,HNRNPC,HNRNPAB,ZMAT3,BTF3,SNRPB,PSMD14,FBXW11,RPS26,DHX9,PSMA5,NEDD8,HNRNPK,MEPCE,PHF1,STRBP,RPSA,TP53,H2AX,TFCP2,EXOC3,DNAJC2,NUPR1,GTF2B,SYNCRIP,ALYREF,FZR1,RPS16,CAND1,RBM42,TMPO,CDC5L,ENY2,RBM17,COPS5,GAPDH,API5,H2AC4,SNRNP70,AKAP8L,TMOD2,RPL27,BAP1,RNF113A,DLAT,HSPA5,AGO1,RPA2,ZNF326,EIF2B3,HEXIM1,STAT6,PSPC1,RPS3,UBN1,RBMX2,SRP54,KCTD9,SMURF1,SUB1,PRKACB,EIF3G,SPOP,RC3H2,ATP1A1,IGF2BP1,UBE2H,TRIP4,ARGLU1,HNRNPA2B1,PCNA,SRSF7,RPS24,EMC8,TRIM37,RAD21,SSRP1,NAA15,B3GNT2,ACTN4,JUN,LGR4,EZH2,NGB,RPS11,SART3,RPL9,THOC2,PHB1,OCRL,SPTAN1,ZBED4,HNRNPA1,RB1CC1,HNRNPD,DICER1,FBXW4,BIRC2,TXNL1,G3BP2,WDR77,PPP1CB,ABCB1,USP39,ATP5PO,PPARG,EMC9,RSRC1,SNRPD1,RPL37A,RPS9,SEC61B,ACTB,SNRPB2,NDUFAF4,RPL19,CUL2,CUL3,GGH,BRCA1,RPS5,RIT1,NKRF,ZC3H11A,THRAP3,VRK1,PSEN1,SMN1,FBP1,MAP2K3,MAP1LC3B,LBR,ILF2,SRP72,RCHY1,ARL10,DCUN1D1,EIF2B2,TOP1,THOC1,TOMM70,CDK9,MDM2,ZBTB2,MOV10,GRSF1,HDAC6,EXOC2,RPA3,SQSTM1,TMEM126B,MTDH,DGCR8,RPL4,FBXW7,PIAS1,AATF,UTP23,ATG16L1,RPS14,METTL14,HNRNPH3,RPL26L1,RARS1,RPLP0,CCNF,METAP2,EIF2AK2,TLR8,RTRAF,PRKRA,PTEN,TRIM24,UBE2I,NDN,TMOD3,VIRMA,FBXO7,RUNX1,NONO,AR,DNAJC8,USP14,IVNS1ABP |
| 1.410e-09 | -20.38 | MFF (mitochondrial fission factor) | protein interactions | 56947 | 176 | 87 | 19454 | 5460 |
NRM,MTCH2,TFRC,UNC50,STX8,PDE2A,FKBP8,SLC7A14,ADIPOQ,SLC25A46,TMEM42,RAC2,SEC23A,AIFM1,PTPN1,ARL10,CNIH1,AIG1,ANKRD46,CDC42,SEC22B,TRAM1L1,RPA2,SAMM50,TMEM254,MAVS,SQSTM1,RPA3,CCDC126,TMX2,TEX264,TOMM20,SLC7A1,FBXW7,CYBC1,CDIPT,OPTN,PLP1,SLC7A8,MGST3,CYB5B,AQP3,PTRH2,ATP6V0B,BAG2,TMEM88,SACM1L,TMEM60,GJB1,FATE1,MARCHF5,HAX1,PEX3,FXYD6,RHOG,TRAF3IP3,TMEM97,TSPO2,TMEM237,COX14,RHOH,RND2,SEC22A,DUSP22,CTXN3,TOMM22,GOSR2,MTX2,BET1,CEND1,FAM3C,AKAP1,JAGN1,EXD2,PXMP2,STX7,OPRM1,FIS1,PLN,HTRA2,FCER1G,PSMD14,YWHAZ,RETREG3,RMDN3,TMEM229B,TAX1BP1 |
| 1.431e-09 | -20.37 | HSPH1 (heat shock protein family H (Hsp110) member 1) | protein interactions | 10808 | 407 | 170 | 19454 | 5460 |
HNRNPF,PSMD12,HNRNPA2B1,DNAJB4,RPAP3,RAB4A,GDI2,METTL21A,EZH2,HGS,MOB3C,ARFGEF1,B3GNT2,RAF1,PPP2R1A,DYNC1I2,CCAR2,RPS10,HSP90AB1,DHX15,WDR44,EGLN3,ELK1,PSMB5,PPP2CB,PHB1,CBFB,AGR2,PSMD10,YWHAB,WWP2,PSMD3,IFI16,ATG9A,DDRGK1,ZNF207,CTNNB1,ATG7,YWHAG,YWHAH,CPEB1,STAU1,UFL1,G3BP2,PSMC1,DNAJC3,STK26,HSPA8,PPT1,MAP2K1,USP39,VAV2,PIH1D1,CAV2,PAFAH1B1,STXBP1,EDEM3,PPP1CB,PSMD6,FBXO22,TAGLN2,NCKAP1,ESR2,LMBR1L,PRMT5,PSMD14,BRCA1,CCT2,DNAJB6,ILK,SP1,HSP90AA1,NTRK3,GRB10,CUL3,SFN,MYC,ACO2,MCM3,PSMD1,BTF3,SAMHD1,HSPE1,HUWE1,NEDD8,VTA1,MEPCE,GLUL,MAP1B,FAF1,TAGLN3,EMC2,HAPSTR1,TFCP2,HSPA13,PSMC3,TP53,MTCH2,MRPL47,FBP1,MAP2K3,CGAS,FZR1,MYL12A,TMPO,POLE3,CD274,SEC23A,ADD1,PREP,PSMD7,SHC1,H2AC4,DNAJC7,CNN3,TPM3,CSNK2A1,COPS5,HDAC6,NF2,HSPA5,TUSC2,GRPEL1,EIF4E,UGP2,BAP1,RPA3,PPM1G,SQSTM1,PGK1,MIS12,LSM2,GRM2,DCTN4,JUP,RPA2,HECTD1,ACACA,UBE2M,HEXIM1,CCND1,PSMC4,CFTR,COMMD3,CHMP5,ADRM1,KCTD9,SRC,VIRMA,NMI,SH3BGRL,CTNNA1,PAFAH1B3,CREB1,CCNF,MSN,PTEN,PSMC5,GANAB,PIP4K2C,RC3H2,BICD2,SPOP,UBE2H,PDCD4,CSK,CARS1,USP14,DNAJC8,CFL1 |
| 1.434e-09 | -20.36 | ADCY9 (adenylate cyclase 9) | protein interactions | 115 | 145 | 75 | 19454 | 5460 |
KRAS,FKBP8,SAR1B,TMT1A,CYP2C9,RAB4A,PTRH2,STIM1,RPN1,CTXN1,RND3,TOP3B,DNAJC25,RHOH,DNAJC1,ARF6,CAV1,LMAN1,DIRAS3,PXYLP1,TMPO,STX6,RPRM,PTPN1,RAB35,RAC2,GJA1,HSD17B11,ESYT1,RHOG,SLC20A1,HSPB1,HAX1,DNAJC7,ANKMY2,RAB5C,LAMP2,LAMP3,PIANP,NLGN1,DNAJC22,PXMP2,STX7,RHOU,RAB5A,DERL1,RAB9A,LRRTM3,SSR1,LEMD3,AVPR1B,ARL15,FUT8,GINM1,ST7,RND2,OTULINL,CDC42,SEC62,LGALS3,POPDC2,RHOJ,VIRMA,NLGN2,SEC63,ALG5,ANAPC2,SEC61B,LGALS8,RHOB,LAMTOR1,RAB11A,RAB2A,DNAJC5,MBLAC2 |
| 1.488e-09 | -20.33 | negative regulation of intracellular signal transduction | biological process | GO:1902532 | 599 | 244 | 18204 | 5365 |
MIR16-1,RNF152,NKIRAS2,EID2,NLRP2,OPRL1,TBC1D10C,MIR424,TNFAIP1,DUSP6,NHERF1,PSMD10,PDE2A,NUP62,HAPSTR1,TMSB4X,MAPKAPK5,PPIF,RHOH,TBK1,CYRIB,DUSP9,MIR17,CD2AP,FKTN,CASTOR2,NLRP3,MIR145,TAF9,TRIM32,CCN3,SEC13,PHB1,DUSP1,ADIPOQ,IL10,MUL1,KCTD10,MIR101-1,FBP1,NOG,ATF3,NFKBIL1,EMILIN1,ARHGAP12,CCAR2,STK38,ADIPOR1,DUSP10,MIR23A,PYCARD,CREB3,STK11,CLU,MIR205,RGS2,MINAR1,TMBIM6,EPHA2,TXNDC12,CXCL12,BCL6,MIRLET7G,PYCR1,MIR195,NF2,MIR29A,NFE2L2,EPO,FBXO7,TRIM15,CARD19,IVNS1ABP,PPM1B,LMO3,PPARG,MIR503,MIR218-1,PAQR3,CCDC22,PIK3R2,CUL3,HELLS,YWHAZ,HOMER3,PRKACB,PPP2R1A,SESN2,SLA2,AZI2,SYNJ2BP,PDCD4,MIR15A,MIR34A,SOD2,LPAR1,MDM2,MIR133B,MIR34B,PAFAH1B1,DDIT3,TNFAIP8L1,TLR4,APLNR,ATF4,NONO,MIR140,MIR26B,ACKR3,SRC,SH3BP4,MIR34C,NKIRAS1,DAG1,PTPN1,GSK3A,SYVN1,CDK5RAP3,PARL,DEFB114,PTEN,MIR29C,NLRP6,ATP2B4,MIR200C,BCL2L1,KDM1A,STAT1,MIR130A,MIR221,IFI35,SNAI2,DLG1,IGBP1,RRN3,LITAF,MIR497,UBE2D1,UBE2N,MET,MIR20A,XBP1,ARHGAP25,MIR206,GSTP1,HYAL2,CTNNB1,SESN3,TNFAIP3,GPX1,NCK1,MIR9-1,OTUD7B,SPRED2,KICS2,INPP5E,TLE1,SPRED1,VDAC2,UBE2W,NFKBIA,SIRT7,CRYBA1,MAP2K3,DUSP3,CHP1,TGFB2,MIR92B,DDIT4,DUSP26,SELENOS,SMAD4,TANK,GREM1,DRD3,RNF167,PTPN22,ZMYND11,IL1B,DYRK1A,MIOS,DKK1,NOP53,AKT1,TPT1,OPTN,VGLL4,MAD2L1BP,CDKN2D,CAV3,MSTN,NDUFS3,ING2,CAV1,NMI,MIR204,SAR1B,CPNE1,MIR149,MIR375,PPP1R10,LILRB4,MIR146A,MTM1,MIR21,CNKSR3,HDAC3,LDLRAD4,HTRA2,TMEM127,TLR9,UBE2B,HACD3,PEBP1,FLCN,IGF1R,CSK,STAMBP,MYC,DUSP19,HSPB1,PYDC2,MMP9,PPIA,MIR223,YWHAG,UBE3A,DYRK2,EPHA4,MIR185,MIR449A,PRNP,SPRY1,BTN2A2,PPARA,RNF34,MIF,PPP2CB,MIR885,SNIP1,FAM89B,INPP5K,MIR132,ENO1 |
| 1.500e-09 | -20.32 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | REACTOME pathways | R-HSA-174184 | 73 | 48 | 10285 | 3229 |
PSMD7,PSME1,CDK1,PSMD10,UBB,UBA52,CDC26,PSMD14,PSMC4,PSMB5,PSMA3,PSMB1,CDC20,PSMB7,PSMD3,CDC16,PSMB3,BUB3,PSMB6,PSMA2,PSMA5,PSMB10,PSMC5,PSMB11,PSMA4,ANAPC4,SEM1,PSMB9,CDC23,PSMB4,ANAPC15,ANAPC2,PSMD6,PSME2,UBE2D1,CCNA2,ANAPC11,PSMD4,RPS27A,PSMA1,PSMC3,PSMC1,PSMD12,ANAPC16,PSMA6,MAD2L1,PSMD1,PSMB2 |
| 1.510e-09 | -20.31 | GATD3 (glutamine amidotransferase class 1 domain containing 3) | protein interactions | 8209 | 387 | 163 | 19454 | 5460 |
NDUFAF4,CLIC4,MRPL23,ATP5F1B,PRDX2,MRPL13,TRMT11,DLST,IRF2,TACO1,MDH1,NOA1,MRPS25,MRPL16,AK3,PYCR1,PMPCA,HNRNPAB,ACO2,MRPS7,NT5C3A,SRI,OXCT1,PHB2,MRPL57,NDUFS2,HADHA,ATP5F1E,ATP5IF1,ATPAF2,NDUFA5,ATP5PO,MRPS18A,MRPL12,NDUFAF3,PRDX3,IDH3B,DUSP14,LAP3,H1-5,PNPLA8,NDUFS8,HNRNPL,PHB1,MRPS26,AGR2,GSTO1,MRPL18,NDUFV2,MRPL9,STOML2,FRA10AC1,MRPS35,DDX50,MTRF1,CLPX,SAR1B,PAX6,MRPS17,ATP5F1D,KGD4,ETFA,MRPS11,HINT2,THNSL1,PREPL,HSPD1,NDUFA12,PDHA1,NDUFS6,NUDT19,ERLIN2,GTF2E2,ETFB,HSDL2,DDAH2,SUCLG2,TXNDC12,CPT2,PNP,CTSB,ACAT1,PTPMT1,GLTP,MRPS28,ENO1,MRPL53,FXN,UBE2H,OAT,MRPS16,MTPN,ATP5F1A,GSTK1,PYCR2,NDUFAF2,NDUFB10,POLDIP2,MRPL20,GRPEL1,MRPL40,MRPL41,PDHB,MRPL17,NME4,PRDX6,GFM1,DLAT,TWNK,IDH3A,GSTP1,IDH2,QRSL1,SPRYD4,MRPS34,NDUFAB1,MRPL10,SPR,PCK2,MRPS23,MRPL24,ATP5PD,DBT,MRPL50,COX4I1,MGME1,SDHB,MRPS9,SSBP1,TRMT5,SNRNP70,LYPLAL1,COPS5,ATP5MG,COX5A,GRSF1,ABHD10,DUSP19,MPST,FASTKD5,MRPL22,MRPS18C,HSPE1,MRPS33,PDE12,THG1L,HSD17B10,HINT1,MRPS18B,ATP5PF,MRPL52,MRPL49,ACADSB,NDUFS3,BCS1L,PGM1,METTL15,GLRX5,HADH,NDUFA2,MRPL47,ATP5PB,CMPK1 |
| 1.521e-09 | -20.30 | FBXO42 (F-box protein 42) | protein interactions | 54455 | 77 | 47 | 19454 | 5460 |
RPL7,TTC9C,COPS7B,HNRNPL,CCT7,RPL8,COPS2,RPL10A,DDX1,RPL6,COPS5,ROCK2,COPS4,PRDX4,RPS13,SLC25A11,CCT8,DHX9,RPL3,HAPSTR1,GJA10,TAB2,PPP4C,RBPJ,TP53,CCT5,RPS7,DDX39A,PPP2R1A,TAB1,SLC25A4,SMURF1,RAB28,STUB1,RPS9,KLK6,GSK3A,CCT2,STK11,ATP1A1,RPL7A,COPS7A,TUFM,ATP5F1A,RPL4,SKP1,SLC25A3 |
| 1.531e-09 | -20.30 | Synthesis of DNA | REACTOME pathways | R-HSA-69239 | 101 | 61 | 10285 | 3229 |
PSMD7,PSMD10,PSME1,GINS4,UBA52,UBB,RB1,PSMD14,POLE3,PSMA3,PSMB5,CDKN1B,ORC5,PSMC4,RFC2,PSMD3,PSMB7,POLD4,PSMB1,MCM6,PSMA2,PSMB6,POLD2,PSMB3,RPA2,MCM4,PSMA4,PSMC5,PSMB11,PSMB10,PSMA5,PSMB9,FZR1,SEM1,RFC3,ORC6,PSME2,RPA3,RFC5,PSMD6,PSMB4,RPS27A,MCM3,PRIM2,PSMD4,RFC4,CCNA2,PCNA,PSMC3,PSMA1,POLE4,PSMD12,POLA2,PSMC1,GINS3,MCM8,CDKN1A,PSMB2,PSMD1,PSMA6,FEN1 |
| 1.542e-09 | -20.29 | HM13 (histocompatibility minor 13) | protein interactions | 81502 | 130 | 69 | 19454 | 5460 |
XBP1,TRAM1,OTULINL,SEC62,TMEM266,BET1,TPT1,CAV2,PDIA2,SAMM50,STOM,SSR1,GHITM,UBAC2,RPA2,AKAP1,DERL1,RAB9A,DDX39B,RPA3,PXMP2,STX7,CMTM6,EMC1,HSCB,PSMB2,UBE2H,NTRK3,CDC73,LMNB1,SEC61B,ODR4,LMBR1L,VIRMA,SEC63,VKORC1L1,AGPAT5,DNAJC25,TP53,RAF1,RAB4A,STIM1,RPN1,COX8A,ABCE1,TMT1A,ATP2B4,MAP1B,FLOT1,KRAS,COPS5,CCR6,RAB5C,SLC25A46,FAM20C,RNF139,RB1CC1,ESYT1,RHOG,RAC2,HSD17B11,ADGRG1,PTPN1,RAB35,HRAS,ELK1,LMAN1,DNAJC1,HNRNPL |
| 1.542e-09 | -20.29 | CLIC4 (chloride intracellular channel 4) | protein interactions | 25932 | 130 | 69 | 19454 | 5460 |
LSM3,CLIC2,SHC1,HNRNPA1,DAG1,COX5A,HSP90AB1,PRNP,PSMB1,GATD3,HDHD3,COX4I1,PSMB4,CRKL,RAB4A,GLRX5,HADH,CMPK1,TPD52,E2F4,SEPHS1,MPST,SAR1B,G3BP1,GUK1,PSMA1,PSMA5,ACADS,PSMA2,HINT2,HINT1,TAGLN3,ICAM1,FXN,YWHAZ,MTPN,ST13,CASP4,CSK,MYC,ACO2,RAB11A,PMPCA,RABIF,DDAH2,ESR2,PRDX2,TAGLN2,CTSB,ACTB,ENO1,GSTP1,ARCN1,PSMB7,RPA2,IDH2,NDUFAB1,LAP3,DDAH1,SPR,CRYZ,HSPA8,HNRNPH2,PRDX6,PSMA3,BAP1,RPA3,PYM1,SOD1 |
| 1.548e-09 | -20.29 | FOXA1 (forkhead box A1) | protein interactions | 3169 | 513 | 206 | 19454 | 5460 |
DEK,RPL13A,PRKRA,ASCC1,GMPS,RACGAP1,PPP1CC,AR,CHMP2B,PIAS1,AATF,GTF2I,ARPC2,PPIH,RPA3,DCTN6,PNO1,RPLP0,NOL7,HNRNPH3,MRPS34,CDK1,DCTN4,STOM,CHMP1A,CNP,TPT1,ARF6,EIF4E2,UBP1,BRD3,MPHOSPH10,GRSF1,TLE1,VTA1,SNRPG,PAK1IP1,LSM4,VRK1,THRAP3,NOC4L,HAPSTR1,SNAP23,NKRF,DHRS7B,UAP1,DDX39A,MAP1LC3B,CD2BP2,FCF1,NDUFA2,MRPL11,NDUFAF4,B4GAT1,PRDX2,RPF1,RBBP4,LGALS3,PARP2,RPS5,RIT1,ARMT1,RFC5,MCM3,NOP16,NDUFAF6,ATAD1,NOP53,ARCN1,TIMM13,SRSF10,NDUFS8,CGGBP1,HSBP1,RPL7,PBDC1,XPO5,HP1BP3,CETN3,RPL8,MRTO4,CD58,MPHOSPH6,WDR12,HBA1,HSPB8,TRA2A,HMGA1,DPY30,VPS26A,MRPS35,SSRP1,HS2ST1,BAG2,SRSF7,ZYX,AP2S1,NME1,EXOSC3,NUP153,BUD23,RSL24D1,DHRS13,KIAA1958,MRPS28,RBMX2,PTPMT1,MACROH2A1,SF3B6,CREB1,EXOSC1,ALKBH5,RRP7A,DNAJC10,RPS17,PHKA1,FOXA3,GRPEL1,MARS1,RPS15,EXOSC4,HNRNPH2,RPL27,TXNDC17,TRIM3,BANF1,TFB1M,SDCBP,RPA2,NTPCR,XBP1,SUMO1,TMPO,SPPL3,DSTN,RPL32,NDUFB4,MGME1,UBE2N,ALYREF,SEC14L5,CMSS1,SELENOS,RBM17,SRSF12,CHMP1B,H3C1,CSE1L,TMEM33,RPL3,NOSIP,ATP5PF,CARD19,DDX42,TFCP2,RBM34,H2AX,UBL4A,CBX5,RPL10,LDB2,SF3B4,SMU1,FIS1,PRSS1,CIRBP,BTF3,LDB1,MLF2,PRMT6,HNRNPC,HIGD2A,TRA2B,STAU1,MROH8,RFC4,OGFOD3,CSNK1A1,PIH1D1,DHRS4,UQCRH,LANCL1,RMND1,ISG20L2,FAM98A,HNRNPL,SNRPA1,DIPK2A,WDR82,EED,POLR2L,FUBP3,YWHAB,MAGOH,AGR2,XPO1,DDRGK1,NGDN,GSTM3,DDX50,RPL28,UTP25,SATB1,RBM3,NDUFA12,DLX1 |
| 1.559e-09 | -20.28 | PMPCB (peptidase, mitochondrial processing subunit beta) | protein interactions | 9512 | 367 | 156 | 19454 | 5460 |
MRPS25,RIT1,BOLA1,CUL3,PYCR1,PMPCA,HNRNPAB,MYC,FMC1,JPT1,MRPL16,MRPL23,TAMM41,ATP5F1B,NDUFAF4,DES,DLST,TACO1,MRPL13,SOST,MRPS18A,ATP5PO,NDUFA5,DUSP14,MRPL12,NDUFAF3,PRDX3,DHRS4,DUSP26,MRPL57,NDUFS2,HSCB,MRPS7,HADHA,NUP50,TXNL1,RHOG,MRPL18,GSTO1,PPM1K,MRPS26,MRPS35,STOML2,CLPX,ACP6,MRPL9,NDUFV2,LYRM2,HNRNPL,ADCK1,PNPLA8,NDUFS8,HDHD5,FBXO32,PHB1,RPRD1A,DEFB1,PDHA1,NDUFS6,NDUFA12,ETFB,HSDL2,CCS,ETFA,KGD4,ATP5F1D,KRAS,CHCHD2,HNRNPDL,MRPS17,THNSL1,PREPL,HSPD1,HINT2,MRPS16,UBE2H,FXN,OAT,PYCR2,NDUFAF2,DNAJC8,GMPS,ATP5F1A,SUCLG2,ENO1,UQCRC2,MRPL53,CCNF,ACAT1,PTPMT1,MRPS28,SLC11A2,PAK5,QRSL1,RPA2,SPRYD4,MRPS34,WTAP,ACACA,PCK2,COQ8B,UQCRC1,NDUFAB1,MRPL10,MRPL40,MRPL41,MRPL17,PDHB,NME4,MRPL20,POLDIP2,OGDHL,GRPEL1,MAIP1,RPA3,GFM1,DLAT,TWNK,PTGER4,NPSR1,COX5A,GRSF1,MOV10,LYPLAL1,HCRT,MRPL50,MRPL24,MRPS23,DBT,ATP5PD,COX4I1,MRPS9,COQ8A,NDUFS3,CCDC69,MRPL51,MRPL49,MRPL47,NDUFA2,ATP5PB,BCS1L,HADH,PPIF,HSPE1,MRPS33,PDE12,ABHD10,SOCS2,MRPL22,FASTKD5,MRPS18C,ATP5PF,MRPL52,HSD17B10,THG1L,MRPS18B |
| 1.586e-09 | -20.26 | SDCBP (syndecan binding protein) | protein interactions | 6386 | 422 | 175 | 19454 | 5460 |
LGALS8,REEP6,RHOJ,UBB,RPL22,OPTN,TRIM27,HEXIM2,PTEN,CTDSP1,LMNA,GRM2,CHMP1A,ZCCHC17,DCTD,RARS1,MYLIP,KCNH1,EEF1E1,FTH1,CDK7,NF2,LDOC1,MBD3,TNFAIP8L3,RHOU,GRIA2,CCDC106,SQSTM1,EIF5A2,CD9,CGAS,FAM118B,TNKS,PDLIM4,PPARA,WASL,PDE2A,LTBR,MRFAP1,RHOB,TNFAIP8,MOBP,ILK,CBR3,SCG3,RAB11A,TSN,SIAH1,LGALS3,GPR37,MAD2L1,GGPS1,GRIA1,PNMA1,GKAP1,HSCB,LZTFL1,RNF11,FTL,FOXP2,GRXCR1,NKAPD1,TRAF6,STX1A,C2CD2L,MED4,INO80E,SNX1,CGGBP1,HSBP1,DNM2,EZH2,RAF1,IFNGR1,ZBTB14,UBE2A,ANP32B,MRFAP1L1,SYPL1,FHL3,SRSF7,LSM6,KCNJ2,TRIM32,SUB1,CEP85,PCBD1,TRIM54,KCTD9,DYRK1A,CDIPT,SYNGR1,SDCBP,SYS1,HBB,SCLT1,CHIC2,CDC42,UBE2K,LITAF,MARS1,EXOSC4,KARS1,RPRM,PDE9A,COX4I1,RAC2,MINDY3,TFCP2,RP9,NUPR1,TSPAN3,KBTBD4,EMILIN3,TOLLIP,RPIA,SCML1,GNMT,EIF1AD,RUSF1,SNIP1,YIF1A,THG1L,RBBP8,LAMTOR1,RPS26,ZNF343,HNRNPC,CDKN2D,LDHB,DRAP1,LDB2,FBXO22,MANSC1,GRIK1,SDC2,FAM8A1,CAV2,PIH1D1,PSMB3,PRR13,UFL1,DDX39B,SNRPA,TIFA,RAB5A,PDZK1IP1,IFI16,PFDN5,ZCCHC10,NT5C2,DDRGK1,RHOH,TCF21,PSME2,RPRD1A,CD63,SDC4,HOMER3,SULT1B1,PNMA2,KLHL12,ODAM,PTS,SOX2,SSNA1,MATN4,LEPROTL1,RPL28,DCTPP1,S100B,EWSR1,EFNB1,SREK1IP1 |
| 1.587e-09 | -20.26 | Cyclin A:Cdk2-associated events at S phase entry | REACTOME pathways | R-HSA-69656 | 71 | 47 | 10285 | 3229 |
CDKN1A,MYC,PSMC1,PSMD12,PSMB2,PSMD1,PSMA6,PSME2,PSMB4,PSMD6,SEM1,PSMB9,FZR1,MAX,PSMC3,PSMA1,RPS27A,CKS1B,CCNA2,PSMD4,PSMB7,PSMD3,PSMB1,PSMB5,PSMA3,CDK4,PSMC4,CDKN1B,PSMA4,PSMA5,CCNH,PSMB10,PSMC5,PSMB6,PSMA2,PSMB3,PSMD10,PSME1,CCND1,SKP1,CDK7,MNAT1,PSMD7,RB1,PSMD14,UBA52,UBB |
| 1.589e-09 | -20.26 | G1/S Transition | REACTOME pathways | R-HSA-69206 | 119 | 69 | 10285 | 3229 |
RPA2,PSMB3,MCM6,PSMA2,PSMB6,PSMC5,PSMA5,CCNH,PSMB10,PSMA4,MCM4,CDKN1B,PSMC4,ORC5,CDK4,PSMB5,PSMA3,PSMB1,PSMD3,PSMB7,UBB,PPP2R1A,UBA52,PSMD14,RB1,POLE3,PSMD7,MNAT1,CDK7,SKP1,CDK1,CCND1,PSME1,PSMD10,AKT3,PSMA6,AKT1,PSMB2,PSMD1,AKT2,PPP2CB,CDC7,PSMD12,CCNB1,PSMC1,POLA2,MYC,POLE4,CDKN1A,MCM8,MCM3,TFDP2,PSMD4,PRIM2,CKS1B,CCNA2,TYMS,RPS27A,PSMA1,PSMC3,PCNA,MAX,PSMB9,SEM1,PSMD6,PSMB4,ORC6,PSME2,RPA3 |
| 1.600e-09 | -20.25 | RAD23B (RAD23 homolog B, nucleotide excision repair protein) | protein interactions | 5887 | 219 | 103 | 19454 | 5460 |
PSMC5,OPTN,STUB1,PSMA6,EIF4A3,UBB,ADRM1,USP14,PSMB2,MEA1,LCP1,RPA3,BAP1,BCL6,GTF2I,HMGB1,CDK7,PSMC4,TPT1,PAQR3,SPR,UBE2M,STAT6,PSMB1,CD274,UBE2N,G6PD,KCTD3,CGAS,PRNP,HDAC6,MPG,PSMD7,H2AC4,PDE12,SEM1,H3C1,PSMA5,EEF1A1,H2AX,PSMC3,RAD23B,CDC7,UBE2V2,PSMB6,ESR2,MAD2L2,USP5,APEX1,PSMD4,TAX1BP1,PSMD6,HMGCS1,PSMD1,DRAP1,MYC,CDKN3,PSMA4,BRCA1,PSMD14,MYO6,HSPA8,TXNL1,YAF2,NUBP2,PSMA3,PSMC1,HSCB,PSMB3,PSMB7,IGBP1,CORO1C,CETN3,PSMB4,PSMB5,PPIA,EGLN3,HSP90AB1,CETN2,KCTD10,SUMO3,DDRGK1,MAPK4,PDIA3,PSMD3,WWP2,AHSA1,POU5F1,PSMD10,EWSR1,UBE3A,ZYX,PSMD12,RFC2,PSMA2,UFM1,PSMA1,XPNPEP1,SOX2,ISG15,RAF1,PNMA5,PPIL3 |
| 1.600e-09 | -20.25 | FAM98A (family with sequence similarity 98 member A) | protein interactions | 25940 | 219 | 103 | 19454 | 5460 |
MIR7-3,MIR107,MIR29A,MIR205,MIR10B,RPA3,MIR34C,MIRLET7I,LSM12,TOX4,RPA2,MIR7-1,MIR21,HEXIM1,MIR34B,MIR1-2,PPP1R10,CTTN,MIR16-1,PSPC1,CCNF,RTRAF,RC3H2,MIR145,SPOP,IGF2BP1,RACGAP1,ANAPC15,MIR16-2,MIRLET7C,MIR200A,SNIP1,MIR9-3,MIR20A,MIR17,TAF2,YTHDF2,KBTBD4,MIR15A,MIR200C,MIRLET7G,FZR1,CAND1,RPS16,MIR25,SNRNP70,MIR34A,USP15,DNAJC7,COPS5,HDAC6,STAU1,FXR2,UFL1,CMAS,MIR106A,EMG1,HSPA8,LARP4B,NUFIP2,EIF4B,ESR2,MIRLET7D,MIRLET7B,BRCA1,MIR363,CUL2,CUL3,MYC,COPS7A,BTF3,MIR98,MIR155,G3BP1,UBE2A,MIR9-2,RTCB,RAF1,MSX2,ISG15,MIR222,SOX2,LYAR,MIR9-1,COPS7B,FBXO32,FUBP3,MIR7-2,PHB1,FBXO31,MIR214,MIR141,MIR31,ZCCHC9,MIR140,MIR221,DDX1,MIR143,WWP2,DDRGK1,YWHAG,YWHAH,MIR29C |
| 1.600e-09 | -20.25 | NFKBIA (NFKB inhibitor alpha) | protein interactions | 4792 | 219 | 103 | 19454 | 5460 |
MED31,CSNK1A1,USP39,G3BP2,SKP1,UBE2D3,BIRC2,HDAC5,EP300,TRIM22,PTRHD1,TBC1D24,SPECC1L,COP1,MDH1,ARMT1,FBXW11,UFD1,MCM3,TBCE,PSMA4,POLR2B,JAK2,STAT1,TRIM46,DYNLL1,CHAC2,NFKBIA,NFKBIB,UBE2S,POLR2C,RWDD3,PIR,JUN,NUP153,ENKD1,PSMA2,TNF,PSMA1,RPAP3,SLC25A5,UBFD1,RPL23,HSPB1,AVL9,UBE2D1,IKBKB,HNRNPA1,XPO1,MAP3K14,NKIRAS1,PIK3R1,PSMD3,RPL6,EGLN3,SUMO2,COPS2,UBE2M,PRKCA,HECTD1,ST7,SUMO1,CAPN1,OGDHL,CLU,GTF2I,HDAC3,SMC4,MAVS,TCEA1,UBE2E3,USP14,AKT1,ATF4,UBE2L3,SFRP4,DDAH2,SRC,MAP3K3,SLC25A4,YES1,CSNK2B,CIMAP1B,TRIM27,UBE2I,RPS3,EIF2AK2,TUBA1B,CAPN2,RNF121,TBC1D4,SOCS3,GNPNAT1,TBK1,FBP1,TP53,RNF115,GNG5,BCL10,CSNK2A1,NFKB1,NKIRAS2,PTPN1 |
| 1.611e-09 | -20.25 | SCCPDH (saccharopine dehydrogenase (putative)) | protein interactions | 51097 | 179 | 88 | 19454 | 5460 |
RNF181,SLC25A20,NDUFS3,PGM1,MTCH2,CCDC47,PTGES3,EMC2,TAL2,GNG5,SFXN1,RAB1A,MED21,ATP5MG,COX5A,EMC4,NFKB1,POLE3,RPL35A,COX4I1,HACD3,CYC1,RPA2,COX6C,UQCRC1,HSPA5,MIEN1,PDHB,NDUFC2,DPAGT1,SQSTM1,RPA3,PAIP2,ATP5F1A,UQCRQ,CPT2,MGST3,UQCRC2,CYB5B,MOB3C,RAB6B,RAB4A,BZW2,PDHA1,RPN1,TMEM59,CYB5R1,PARM1,B3GNT2,VDAC1,ACTR1B,HECTD3,NDUFA4,NDUFB8,STOML2,PRDX1,NDUFS8,GLRX,CORO1C,PHB1,OCIAD2,FEZ1,SLC25A3,CPLX2,ATP5PO,PRDX3,PGRMC1,TOMM22,STAU1,PHB2,HSCB,NDUFS2,HADHA,ATP5MK,TMEM160,MDH1,ICAM1,BRCA1,PCCB,TOMM40,RAB11A,USP13,ESR2,ACTB,ATP5F1B,SEC61B,CYB5R3,VDAC2 |
| 1.614e-09 | -20.24 | PSMD6 (proteasome 26S subunit, non-ATPase 6) | protein interactions | 9861 | 299 | 132 | 19454 | 5460 |
PABPC1,CCT8,UBE3A,RUVBL2,PSMA1,KRAS,PSMA2,HNRNPF,RBBP7,AHCYL1,SSRP1,RPS27A,PSMD12,MAX,ISG15,PPP2R1A,KDELR1,PLS3,MOB3C,PSMB5,PSMB4,PSME2,DYNC1I2,KCTD10,DHX15,EGLN3,PSMD3,ATG9A,DDRGK1,DKK1,AGR2,TRAF6,PSMD10,DDX39B,RMND5B,PSMA3,NUBP2,EP300,HDAC5,HSPA8,STAU1,MRPL57,UFL1,RNF11,DDI1,PSMC1,PSMB3,TIMM13,MED23,PSMB7,CMTM7,PRMT5,PSMD6,ACTB,TAX1BP1,PSMD4,NCKAP1,ESR2,PSMB6,PSMA4,CUL3,PSMD1,PSMD14,BRCA1,RIT1,FAM107A,PSME1,MAP1B,HSD17B10,HUWE1,PSMA5,SEM1,FKBP8,MRPL22,FBXO25,PSMB10,MEPCE,TP53,NDUFA2,PSMB9,EEF1A1,TMEM31,CAMK1,PSMC3,RAD23B,ZFAND2A,TAF2,CD274,PTPN1,PSMB1,PRNP,FZR1,EMC4,ATP1B1,ZFAND2B,HDAC6,PPM1D,PSMD7,RPL24,CCDC92,MAP4,USP15,TSNAX,BAP1,RPA3,HSPA5,EIF4E,PSMC4,UBLCP1,PAAF1,METTL14,GRM2,LMNA,RPA2,ACACA,UBE2M,PSMA6,CCNF,PSMC5,GANAB,ADRM1,VIRMA,PSMB2,GORASP2,AR,USP14,STK24,ATP1B3,MAPRE1,UBE2H,PSMG3,NAPA |
| 1.616e-09 | -20.24 | RANBP9 (RAN binding protein 9) | protein interactions | 10048 | 425 | 176 | 19454 | 5460 |
RPS2,MAP4,RPL10A,IL17F,COPS5,RPS27L,ADD1,CD4,SSBP1,ALYREF,COX4I1,HBP1,PSMC3,TFRC,DISC1,RBM34,TP53,TNKS2,L1CAM,BACE1,UBE2H,SPOP,LACRT,RPS17,RPF2,RPL7A,SRC,MACROH2A1,RPS3,PSMA6,GSTP1,HEXIM1,SDCBP,RPA2,DDX4,HSPA5,KDM1A,RBM22,GID4,BAP1,SMAD9,DDX1,YWHAB,MAGOH,ARMC8,SPON1,DDX50,HMG20A,TNIK,FABP5,SRSF1,AAMP,SERPINA3,SOX2,RPL28,RPS4X,LECT2,TFG,ZBED1,TRIM21,EWSR1,RUVBL2,RPL31,RCL1,CHTOP,H1-10,MYC,NUFIP2,GRIK1,RANBP10,SAP18,HSPA8,DDX5,LCN1,SPP1,TCEAL9,EXOC2,HDAC6,H2AC14,MRPS23,RPL35A,TNKS,WDCP,SMAD3,RPL12,KRR1,ADAMTS1,CD2BP2,EEF1A1,DRD1,MRPL11,RPS13,CTNND1,ARF4,PAK1IP1,RPL23A,NTRK2,CLEC7A,GLUL,YPEL5,SMAD2,AR,PPP1CC,ZMYND19,NDUFB10,RPL22,CEP97,LDHA,TENT4A,RPL13A,RPS12,CFAP298,UBE2I,TUBA1B,ENO1,NOL7,MET,RPL26L1,JUP,LMNA,CCND1,BRIX1,MTDH,DVL2,SOD1,RPA3,GID8,MED4,MRPL18,TRAF6,HNRNPA1,DYRK1B,CLPX,PRDX1,HMBS,HMGA1,EGLN3,GATD3,HP1BP3,RPL8,MRTO4,RPS11,NDUFS6,NME1,RAF1,MKLN1,HSPD1,MAEA,HNRNPA2B1,CBR3,ILK,BRCA1,LMNB1,PRPF31,CAPG,GGH,NOP16,OPRM1,CUL3,BTG3,ERH,PRDX2,LGALS3,RPF1,BMP1,S100A6,TRMT6,RAN,ATP5PO,PPARG,H1-5,G3BP2,RMND5B,CCDC86,EMG1,NUP50 |
| 1.646e-09 | -20.22 | CLPP (caseinolytic mitochondrial matrix peptidase proteolytic subunit) | protein interactions | 8192 | 555 | 220 | 19454 | 5460 |
FBXO7,ATP5F1A,TUFM,PYCR2,DNAJC19,ACAT1,TECR,GNAI2,CPT2,SLC35E1,CRAT,UBLCP1,PCK2,COQ8B,MTRES1,COX6C,MRPS34,RPA3,IDH3A,SLC2A3,POLDIP2,GRSF1,ATP5MG,SLC2A1,PSMB1,AIFM1,DBT,MRPS23,MRPL24,SLC25A12,AURKAIP1,PPIF,BCS1L,AGPAT5,MRPL11,NDUFA2,DHRS7B,NDUFS3,HSD17B10,TMX3,SLC25A10,FASTKD5,MRPL22,ABHD10,PRDX4,HSPE1,PRPF31,AK3,MTG2,AUH,ACO2,FMC1,PMPCA,PYCR1,VMP1,BLVRA,FYTTD1,NOA1,GPR89A,SEC61B,PELO,CHCHD3,GNB1,TNPO3,NDUFAF4,CLIC4,PARL,MRPL23,TENT5C,IDH3B,RAB6A,PLSCR4,MTX2,ELOVL1,NDUFA5,APOBEC3C,KLF3,TRUB1,TMEM256,HADHA,HSDL1,ATPAF2,EXD2,ATP5MK,HSCB,CLPX,MTRF1,PDIA3,STOML2,MRPS35,MRPS26,TST,RHOG,GATD3,SPRED2,NDUFS8,FAF2,HSDL2,DCAKD,NDUFS6,HSD17B8,HINT2,MRPS11,COX8A,PREPL,HSPD1,THNSL1,NDUFA4,MRPS17,ETFA,NCAPG2,NDUFAF2,GSTK1,NUDT1,ABCG2,OAT,MRPS16,DNAJC10,SEC61A1,MRPS28,PTPMT1,CDIPT,MYG1,IDE,SUCLG2,SRC,TRIM54,NDUFAB1,SNRNP27,MRPL10,PRKCA,QRSL1,RPA2,VPS4B,SPRYD4,IDH2,TWNK,RAB9A,DERL1,GFM1,DLAT,GRPEL1,NME4,MRPL40,MRPL41,LYPLAL1,COX5A,TRMT5,AGPAT1,SHC1,DSTN,GNPAT,SDHB,MRPS9,COQ8A,STT3A,SSBP1,COX4I1,MGME1,ILVBL,SELENOI,ARL6IP5,GLRX5,HADH,METTL15,ATP5PB,RAP1A,MTCH2,MRPL47,GNAI3,SURF4,ACADSB,TMEM165,SLC16A1,THG1L,ATP5PF,MPST,LPCAT3,PDE12,TMEM33,RAB3B,COX11,LDHB,THTPA,FBXW11,MRPS25,TRMT11,TACO1,DLST,ATP5F1B,YIPF5,DHRS4,MRPL12,NDUFAF3,UBAC2,ACAA2,ARG2,MRPS7,SLC37A4,NDUFS2,OXCT1,NDUFV2,CBR4,ETFRF1,PTDSS1,YBEY,FUBP3,HDHD5,MPDU1,PNPLA8,TMEM97,COX14,ETFB,NDUFA12,NUDT19,PDHA1,RPAP3,TMEM87A,SDHC,KGD4 |
| 1.669e-09 | -20.21 | ABC transporter disorders | REACTOME pathways | R-HSA-5619084 | 69 | 46 | 10285 | 3229 |
PSMD10,KCNJ11,SFTPD,PSME1,PSMD7,PSMD14,DERL2,RNF5,UBA52,UBB,PSMB7,PSMD3,PSMB1,OS9,PSMA3,PSMB5,PSMC4,ERLEC1,PSMA4,PSMB10,PSMA5,PSMB11,PSMC5,PSMB6,PSMA2,PSMB3,PSME2,PSMB4,PSMD6,SFTPC,SEM1,PSMB9,PSMC3,PSMA1,RPS27A,ERLIN2,PSMD4,SFTPA1,DERL1,ERLIN1,PSMC1,CFTR,PSMD12,PSMD1,PSMB2,PSMA6 |
| 1.737e-09 | -20.17 | HTT (huntingtin) | protein interactions | 3064 | 356 | 152 | 19454 | 5460 |
MPP1,LSM5,HYPK,SUMO2,HNRNPL,COPS7B,CETN2,HMG20A,HSP90AB1,FEZ1,RAB35,SIN3A,MAP1LC3A,WDR82,TRAF6,IKBKB,SKIC8,HSPB1,IFT25,PIK3R1,CNOT2,HMGA1,ATG9A,LAMP2,CTNNB1,CNOT8,RUVBL1,G3BP1,PSMA1,FLOT1,PABPC1,OSTM1,MRFAP1L1,BAG2,RAB4A,CTSA,HGS,RANBP1,TOP3B,SAP30,TUBA1A,PSMD6,SIAH1,TUBB,DYNLL1,MATR3,DLG4,ZMAT2,PRMT5,PSMD14,LAMTOR1,DNAJB6,CRMP1,SP1,HSP90AA1,RAB11A,OPRM1,PSMA4,GPR17,CREBBP,DSN1,TTC23,UFD1,BAG3,PSMD1,RHEB,EEF1G,NPTN,SKP1,FTL,STX7,ZDHHC17,RAB5A,RAB30,HSPA8,CTBP1,PSMB7,MED31,WDR77,RFXANK,NPY2R,GRM1,STX6,EIF4E2,SSU72,EEF1B2,PSMB1,RAC2,BECN1,PSMD7,MED21,EDEM1,DNAJB2,GAPDH,GOLPH3L,CSNK2A1,GPRASP2,PPIL4,RBCK1,CNOT7,HUWE1,PSMA5,RNF20,ZNF451,TRAFD1,MRFAP1,NEFL,SH3GLB1,GEMIN7,TP53,UBL4A,DUSP10,VIRMA,PPP1R10,LIG3,PSMA6,EIF2AK2,CREB1,OPTN,ZNF655,HEY2,PSMC5,WDR45,UBE2E3,EIF3G,HOXC4,SEC13,AKT1,PSMB2,ST13,USP14,USP8,CRYL1,RPL4,KDM1A,NME4,UBE2K,VPS28,PIAS1,PML,DVL2,CCDC126,PPIH,SQSTM1,RAB9A,SYVN1,LSM12,HAUS2,ING5,SUMO1,PRMT2,COMMD3 |
| 1.777e-09 | -20.15 | Glutaredoxin | gene3d domains | 3.40.30.10 | 126 | 68 | 14470 | 4137 |
NDUFV2,GSTA4,GSTM5,ERP29,CLIC2,MRPL53,GLRX5,GRXCR1,TXNRD3,GSTP1,DIO1,GLRX2,GPX4,SELENOV,TXNDC17,TMX4,TUSC3,GSTT1,GSTA2,GLRX,CLIC4,GSTM3,GDAP1L1,TMX3,TXNL1,PDIA2,PRDX3,GPX5,PDCL,GSTO2,TXNRD1,PRDX1,GPX2,SELENOW,NDUFA2,FAF2,FAF1,GPX7,AGR2,GPX6,DNAJC10,PRDX6,SELENOT,MIEN1,MARS1,GSTM4,GSTM2,PDIA3,PDIA6,PRDX4,DIO3,TXNL4A,TXN,EEF1G,GPX3,PQBP1,GPX1,DIO2,TMX2,GSTA1,PRDX2,HPGDS,SH3BGRL,GSTO1,MRPS25,GSTK1,TXNDC12,GSTT2B |
| 1.859e-09 | -20.10 | MRPS25 (mitochondrial ribosomal protein S25) | protein interactions | 64432 | 255 | 116 | 19454 | 5460 |
RPL7A,TUFM,MRPS16,RC3H2,UBE2H,DNAJC19,CCNF,MRPS28,MRPS21,RPL13A,KLF12,RBMS2,MRPS34,GRM2,ZNF574,TFB1M,KLF4,MTRES1,ZNF770,BAP1,MME,GFM1,RNF113A,MRPL17,RPL4,CRYZ,AATF,GRSF1,MOV10,COPS5,E4F1,SNRNP70,CHCHD1,TMEM70,NOL12,SRP14,SSBP1,MRPS9,ALYREF,MGME1,PRR3,TRMT10B,FZR1,CAND1,CGAS,ZBTB2,SURF6,MRPS23,STRBP,MRPL11,TP53,GTPBP8,APOBEC3D,AURKAIP1,METTL15,GFM2,RPL23A,MRPS18B,MRPS33,FASTKD5,MEPCE,MRPS18C,RPL17,MTG2,MYC,AUH,HNRNPAB,PMPCA,PSMD1,ZNF668,BTF3,MRPL16,MCM8,NOA1,NSA2,RIT1,MCAT,TACO1,MTG1,CCDC90B,RPS9,MRPL23,RPL35,RPL10,RPL19,KBTBD6,ESR2,NGRN,EXD2,PDSS2,UFL1,HSCB,NOP53,MRPS7,MTRF1,MRPS35,MRPL9,DDRGK1,TRA2A,RHOG,MRPL18,MRPS26,GATD3,RMND1,TULP3,PDHA1,OTULIN,PREPL,HSPD1,PCNA,HINT2,SRSF7,MRPS11,KRAS,MRPS17,IMMP2L |
| 1.866e-09 | -20.10 | cellular response to cytokine stimulus | biological process | GO:0071345 | 734 | 290 | 18204 | 5365 |
GPR35,HSP90AB1,CDC42EP4,ZYX,MAVS,SIN3A,PAX6,SOCS3,CAV1,IFI27,IFNB1,EEF1E1,FABP4,CXCL3,MIR146A,LILRB4,IFNA2,CD4,MIR324,CLDN1,AQP4,LILRA2,MIR149,IL4,BRCA1,JAK1,MIR31,MYBL2,SYNCRIP,MIR342,MYD88,SOCS5,IL20RB,ILDR1,HSPA5,PLCB1,IFNK,PCK2,IFIH1,HTRA2,TNFRSF1B,ZFAND6,PADI2,ADIPOR2,DAPK1,CDC42,IFNA10,GPR17,IFNAR1,PTP4A3,TXNDC17,IL6,CREB1,TUBA1B,SFRP1,CCL17,TRAF3IP2,IL12B,FCER1G,TLR3,IL2RB,UBE2K,AKAP12,CCL5,CXCL9,FOXP1,VEGFC,DAPK3,IFNGR1,IRF3,NFIL3,STX8,HAX1,MT1X,OXSR1,CSF2,IL6ST,LILRB1,CNTFR,RPS6KA4,HSPD1,INPP5K,MX1,SRM,IL12A,CCL3,PRL,VPS26B,OAS1,KRT8,BAD,UGCG,MRC1,CCR1,GSK3A,IRF8,SYNGR1,STAT1,ACTN4,STXBP1,PHC1,IRF7,JAK2,IL5,CRKL,IL2,KIT,STAT2,SOX9,CBL,PID1,FAS,CCR5,CCL21,EIF4A2,TOLLIP,RPL13A,IL1R2,CDC42EP2,XBP1,JAGN1,IL2RG,IL18BP,CXCL11,MT3,CCL24,ATP5F1B,NPR2,HYAL2,CTSK,GH1,SLC1A1,IL1A,MIR370,PDCD10,NFKBIA,SRSF7,SMAD4,TANK,CCL20,CXCL1,TNFSF18,STAT6,MAT2A,CCR7,IFNA13,CCR6,IL1B,AKT1,DHX9,CXCR6,UBE2G2,IL3,IL7,NFYB,LILRA1,MKKS,MIR455,GAPDH,EGR1,CHCHD4,IKBKB,IL34,FGF23,EPO,NFE2L2,IL15,PDE1B,MIR493,ACTR2,FZD4,CAPN2,CXCL13,IFI16,IRAK4,OSM,CCL1,IRF1,HELLS,PIK3R1,IL13,LEPR,CAMP,MIR34A,AZI2,TP53,IFNG,SNX10,ICAM1,CXCL8,IL17F,CD47,RRAGA,TLR4,FASLG,LEP,EPS8,CD58,PTPN11,CCL8,KLF4,CCL11,SMARCA5,SRC,LILRA3,GHR,IL18,ACKR3,KCNJ11,NUP35,GREM2,SLC25A5,MRAS,CCL4L1,GPR75,NFKB1,CACNB4,WBP1L,PIGA,IL15RA,CCL18,ILK,B3GNT2,PDE2A,LRAT,TMSB4X,CDK9,PML,HCLS1,FOS,CHI3L1,CCL2,TNFRSF14,IL2RA,CXCL10,STAT5A,CDK4,TBK1,XRCC5,CSNK2B,AIF1,CCL19,VAMP3,CCR2,TIFA,CACYBP,INA,MT2A,SLC12A2,CYP1B1,RAD23B,TLR2,CCL25,RPS16,TRAF6,CXCR3,TFRC,BIRC2,PHB1,DUSP1,RPS3,TRIM6,EDA2R,PDIA3,PDE12,CX3CR1,TRAF2,TRAF1,CRHBP,XCL1,CX3CL1,RAF1,TNF,SHMT1,ZC3H15,PLP2,CCR3,ADIPOR1,IL1RAP,PYCARD,CXCR4,NKX3-1,CXCR1,CCL23,RPL3,CD40,CXCL12,MME,CCR4,SYK |
| 1.876e-09 | -20.09 | TMEM31 (transmembrane protein 31) | protein interactions | 203562 | 198 | 95 | 19454 | 5460 |
ADRM1,UBB,VAMP3,PLP1,PSMC5,SYNGR1,SGTA,SMPD2,MFSD14B,VAMP5,GJB2,NINJ1,TEX264,TMX2,TMEM254,DERL1,CLRN1,BLCAP,PSMC4,TIMMDC1,PLP2,ABHD5,ANKRD46,CXCL9,PTPN1,CAMLG,COX20,CCDC92,PSMD7,BTN2A2,LRAT,TMEM107,ZFAND2B,SLC41A1,TMBIM6,SLC7A14,RHBDD3,DNAJC30,TMEM50A,FKBP8,RDH11,NSDHL,ERG28,YIF1A,TMEM31,PSMC3,SELENOK,RAP1A,PSMD4,TAX1BP1,REEP4,TVP23B,PSMD6,USP5,CYB5R3,RETREG3,FCER1G,CGRRF1,PSMD14,ATP5MC3,PLN,FAXDC2,SLC35E4,PSMD1,UFD1,PSMC1,TMEM203,CRYAB,UBAC2,MMP14,CMTM7,AGTRAP,EHHADH,OTULINL,CTXN3,COX14,TMEM14A,SLC66A2,STX5,SELENOM,FXYD6,PSMD10,C2CD2L,PSMD3,PMP22,TMEM208,HIGD1C,PSMD12,UBE3A,SPTSSA,VAMP2,TMEM182,CTSA,STX12,FAF2 |
| 1.883e-09 | -20.09 | SNRPE (small nuclear ribonucleoprotein polypeptide E) | protein interactions | 6635 | 280 | 125 | 19454 | 5460 |
YWHAH,DDRGK1,DDX23,RBM5,PHB1,SRSF1,IFIT2,OCRL,LSM5,SNRPD3,SNRPA1,LRRC61,DHX15,RAF1,LSM10,CHMP4C,SMNDC1,SF3B5,SART3,SNRPE,HSPD1,CMTR2,TOP2B,EWSR1,SRSF7,TNF,KRAS,CCAR1,MYC,CUL3,CUL2,PRPF31,SNRPB,ARHGAP19,ZCRB1,MYO6,YWHAZ,HSP90AA1,RIT1,RSRC1,PRMT5,SNRPD2,SF3B4,SNRPD1,SNRNP40,GGPS1,ESR2,SNRPB2,WDR77,USP39,EMC9,DDX39B,SNRPA,HSPA8,SF3B1,UFL1,COIL,RBM17,COPS5,SNRNP70,H2AC4,LSM3,HRAS,CAND1,FZR1,DCUN1D1,PRNP,CDK9,RBM42,CWC15,CDC5L,UBL4A,KBTBD4,ESS2,H2AX,CD2BP2,ARHGAP12,ZMYM4,DDX42,IK,CAPN2,GEMIN7,NUPR1,RNF181,CDC40,TSSC4,LSM4,SNRNP48,VRK1,MEPCE,OLA1,SMN1,SNRPG,GEMIN8,RC3H2,LSM6,UBE2H,MAPRE1,CCNF,SF3B6,GCFC2,ZMAT5,SRPK2,VIRMA,SF3A1,WDR83,TXNL4A,SNRPN,SNRNP27,RPA2,GRM2,METTL14,LSM2,HEXIM1,TFIP11,UBE2M,RPA3,BAP1,DDX46,PRPF4,CWF19L1,SQSTM1,RBM22,LSM8,HSPA5 |
| 1.890e-09 | -20.09 | PRKRA (protein activator of interferon induced protein kinase EIF2AK2) | protein interactions | 8575 | 388 | 163 | 19454 | 5460 |
RPL35,RPL7L1,RPF1,ZCCHC7,RPL19,RPL10,APEX1,ZNF22,RPL37A,RPS9,FYTTD1,BRCA1,FTSJ3,DCAF4,RPS26,H1-1,NSA2,MYC,HNRNPC,NOP16,BTF3,ZNF668,ZMAT3,UFL1,STAU1,NOP53,HSPA8,CCDC86,APOBEC3C,RASL10A,SYK,RPL27A,PABPC5,EHHADH,EHD1,TIRAP,RALYL,RPL7,LYAR,RPL8,RPL9,SRSF1,MYEF2,RPLP1,HP1BP3,RPLP2,H2BC17,WDR12,RSBN1L,DICER1,DRG1,IFI16,DDX50,WWP2,RPL6,IFIH1,MAP3K14,DDRGK1,G3BP1,NUP42,HMGN4,RPL28,RPS27A,RPL31,RBM3,PRPSAP1,RPS24,SRSF7,GLE1,RPS11,RBPJ,RPS23,RPL18,RAF1,MAGEB10,MAK16,SOX2,RPL13A,SRPK2,RSL24D1,RPL22,EIF2AK2,PRKRA,FGFBP1,RBMX2,UBE2I,RC3H2,IGF2BP1,STK11,ELAVL2,CDKN2AIP,SNX5,RPF2,RPL7A,RPL26,NPM3,RPS15,DGCR8,FBXW7,RPL4,UTP23,AATF,BRIX1,RPA3,RPL27,BAP1,NLE1,SIRT7,RNF113A,RPL26L1,RPLP0,ZNF574,ZNF770,RPS14,FGF13,CAND1,IFRD2,RPL35A,CGAS,DKC1,ZBTB2,SURF6,RPL12,SYNCRIP,SRP14,RPL32,KRR1,PRR3,RB1,CENPL,SHC1,RPL24,MPHOSPH10,SNRNP70,CDK12,RPS2,RPL10A,MOV10,SPATS2L,APOBEC3F,PAK1IP1,IMP4,RPS13,RPL17,MDC1,RIGI,NKRF,TCOF1,RPL3,RPL23A,DHX9,LLPH,RBM34,POLR2G,ILF2,SRP72,STRBP,TP53,AURKAIP1,APOBEC3D,H2AX,RPL15,FCF1 |
| 1.894e-09 | -20.08 | The role of GTSE1 in G2/M progression after G2 checkpoint | REACTOME pathways | R-HSA-8852276 | 61 | 42 | 10285 | 3229 |
TP53,PSMC3,PSMD14,PSMA1,RPS27A,UBA52,UBB,PSMD4,PSMD10,PSME2,PSMB4,PSME1,CDK1,PSMD6,SEM1,PSMB9,PSMD7,PSMA4,PSMA5,PSMB10,PSMC5,PSMB11,MAPRE1,PSMA2,PSMB6,PSMD1,PSMB2,PSMA6,HSP90AA1,PSMB3,PSMB7,HSP90AB1,PSMD3,PSMB1,FKBPL,CDKN1A,PSMA3,PSMB5,PSMC1,PSMC4,CCNB1,PSMD12 |
| 1.899e-09 | -20.08 | ZBTB1 (zinc finger and BTB domain containing 1) | protein interactions | 22890 | 133 | 70 | 19454 | 5460 |
RPS13,RPS4X,MDC1,FANCG,EWSR1,PCNA,RPL3,SRSF7,TESK2,ZBTB25,RPS11,MTA2,GPBP1L1,RPL18,RPS23,TUBB4B,RPSA,EGLN3,ZBTB2,RPS16,SNRPD3,SNRPA1,TRIR,SPTAN1,CCAR2,SUMO2,H2AZ1,CBFB,RPL8,SRSF1,SDC4,DDX1,HSPB1,RPL24,XPO1,KDM1A,STK38,TWNK,HSPA8,HADHA,RPL27,MFAP1,EIF4B,RPLP0,SLC25A3,RPL27A,RPS14,AKR7A2,H1-5,SF3A1,WDR77,SNRPN,FAM161A,CCDC42,TRAF1,NDN,ACTB,RPL13A,TUBB,ZMYM2,PHF21A,RPS9,UBE2I,CCNF,TUBA1B,SCNM1,BRCA1,AR,RPS29,CUL3 |
| 1.921e-09 | -20.07 | BRD7 (bromodomain containing 7) | protein interactions | 29117 | 628 | 244 | 19454 | 5460 |
PCBD1,RPL7A,SLC25A1,RPF2,IGF2BP1,OAT,STN1,FGFBP1,RBMX2,EIF2S2,ZNF330,PAFAH1B3,LIG3,RPS3,PSPC1,BUB3,MAEL,LUC7L3,SSR1,RNF146,CWF19L1,DDX46,MARS1,HSPA5,ZC3H15,GPRASP2,RPL10A,MAP4,KPNA1,AKAP8L,RPS2,ALYREF,ACSL4,STT3A,MRPS9,SYNCRIP,KLF9,CDC5L,OR8B8,DKC1,TMPO,EGR2,TP53,STRBP,PSMC3,RBM34,NEFL,DHX9,RPL3,SLC16A1,ABCE1,BHLHE40,SLC25A11,KPNA2,HNRNPK,H3C1,ATP1A2,HNRNPAB,MYC,FTSJ3,H1-10,PRMT5,SF3B4,GGT7,DLST,IRF2,ESR2,LRIF1,MATR3,LMO3,SYK,EP300,DDX5,SF3B1,HSPA8,FOS,XRCC5,SMARCD3,RFC4,EEF1G,STAU1,ARHGEF39,FXR2,HNRNPA0,SRSF2,RPL6,ZCCHC10,PTDSS1,DDX50,DRG1,DDX1,AGR2,MAGED2,SRSF1,TRMT61A,TCP1,EIF2S1,FAM98A,ELF1,EEF2,KIF2A,SOX2,TUBA1A,TRMT1L,SMARCB1,ZRANB2,TUBB4B,RTCB,EWSR1,CCT8,PABPC1,ABCF1,PAX6,HNRNPDL,RPS4X,HNRNPF,PPP1CC,TUFM,NONO,AR,ATP5F1A,AP2A1,CDC73,TRIM24,RTRAF,EIF2AK2,ENO1,SLC25A4,FTH1,CNP,MX1,RBFOX2,RPLP0,LMNA,MTDH,KIN,SS18,RPL4,SMC4,NUCKS1,PIK3R2,EIF5B,IRF4,GMPPA,GRSF1,MOV10,BRD3,DNAJC7,LDLR,ACTA2,AIFM1,HACD3,H2AZ1,SRPRA,SLC25A12,DBT,TOP1,PLEKHF2,SOX9,LBR,EEF1A1,YTHDF2,TBK1,SERPINB9,DHRS7B,ILF2,PC,SLC25A10,FASTKD5,FARSA,THRAP3,NOC4L,HUWE1,GGH,MCM3,SAMHD1,SMARCE1,IRF1,HNF1B,ILK,HSP90AA1,BRCA1,AP2M1,ELK3,PARP2,RAN,ENO2,TRMT6,FAM91A1,PRRC2A,TUBB,RPL7L1,RBBP4,ACTB,ACTL6A,WDR77,SLC25A3,ELF5,LARP4B,PPARG,USP39,NUP50,NUBP2,HADHA,UPF3B,G3BP2,ZNF207,BCL7C,HNRNPA1,HMGA1,PIK3R1,PRPF19,LHX2,HNRNPD,WDR12,BRD9,RPLP1,THOC2,RPL8,WDR6,DHX15,RPL7,AGK,NOP58,GTF2E2,RAF1,FEN1,GTPBP1,EZH2,RPN1,PRPSAP1,PCNA,HNRNPA2B1,PPAN,HSPD1,SLC25A5,RFC3,SSRP1,RFC2,SRSF4,GTF3C3,CBX7,DHX16,G3BP1 |
| 1.947e-09 | -20.06 | EED (embryonic ectoderm development) | protein interactions | 8726 | 616 | 240 | 19454 | 5460 |
RPS11,EZH2,RPN1,SAP30,RPL29,B3GNT2,FLOT1,SSRP1,PCGF6,RAD21,PPWD1,RPS27A,GTF3C3,CBX7,ARL5B,RBBP7,RPS24,SRSF7,SRSF8,SLC39A3,HNRNPA2B1,ARGLU1,HSPD1,SLC25A5,RPL23,HNRNPD,KDM2A,TRA2A,HNRNPA1,HMGA1,PRPF19,DHX15,SRSF10,RPL7,NOP58,HP1BP3,KRT8,PHB1,MYEF2,RPL8,THOC2,RPL9,SLC25A3,ADNP,PPP1CB,NRDE2,MTX2,SKP1,EMG1,TXNL1,BRCA1,LMNB1,RFC5,ERH,DYNLL1,RBBP4,B4GALT3,SNRPD2,SNRPD1,RAN,CPSF1,ILF2,MAP1LC3B,LBR,DDX39A,MTA3,MDC1,PRDX4,VRK1,BACH1,TRIM63,CDK2AP2,IGF1R,RING1,RPL23A,TCOF1,RAB1A,EPOP,ZBTB2,MDM2,POLE3,TOP1,PWP2,LDLR,MYBL2,RPL12,SRP14,MACROH2A2,HNRNPH3,HSP90B1,ZCCHC17,LMNA,JUP,SF3A1,RPS14,BRIX1,SS18,MRPL20,DAD1,MBD3,NUCKS1,GTF2I,NPM3,TCEA1,PNO1,SLC39A9,BAHD1,DNAJC8,AR,NONO,ZNF687,RPL22,DEK,RPL13A,MAGOHB,RAB14,PTEN,ENO1,FBLN5,EZH1,TUBA1B,EIF4A3,RPS23,RPL18,MTA2,RPS7,HNRNPDL,RPS4X,RUVBL1,HNRNPF,RUVBL2,FBXO11,ABCF1,RPL31,CBL,DDRGK1,PPIB,BAZ1B,DDX50,HSP90AB1,CCT7,SNRPD3,SNRPA1,RAB1B,HNRNPL,RPS10,EED,FUBP3,SRSF1,SIN3A,CCDC71,CTBP1,RPL27A,EEF1G,PHB2,TRA2B,SRSF2,HNRNPA0,PCGF2,DDX5,HSPA8,SF3B1,RPS28,XRCC5,DDX39B,SNRPA,RCL1,H1-1,RPS26,FTSJ3,H1-10,FBXW11,CCT2,PCCB,HNRNPAB,HNRNPC,MYC,APOBEC3B,ESR2,MATR3,ZMYM2,PHC1,NUPR1,DDX42,CBX3,WBP11,STRBP,IMP3,PHF1,HNRNPK,H3C1,NUP107,DHX9,RPL3,MAP1B,SMCHD1,RPL24,SNRNP70,API5,GAPDH,CDC5L,DKC1,TMPO,BRMS1L,SHPRH,CAND1,RPS16,GATAD1,DSTN,ALYREF,EEF1B2,SYNCRIP,ACACA,LUC7L3,E2F6,UBE2M,ZNF326,RPA2,SMYD3,GTF3C4,UBE2W,PPP1R8,HSPA5,HDAC3,KDM1A,WDR3,HNRNPH2,EXOSC4,KCNMA1,CHRAC1,CFL1,RPL7A,SMARCA5,SRPK2,MACROH2A1,B4GALT1,LIG3,SF3B6,PSPC1,RPS3 |
| 1.949e-09 | -20.06 | AHSA1 (activator of HSP90 ATPase activity 1) | protein interactions | 10598 | 269 | 121 | 19454 | 5460 |
CDK20,RPS4X,HNRNPA2B1,LSM14A,CCT8,RPL31,ZYX,HSPD1,TESK2,EWSR1,DNAJB4,PPID,STIM1,RPS23,RPS11,STX12,RPS7,GFPT1,RPS10,RAB1B,HSP90AB1,EGLN3,PHB1,RPL9,FKBP4,RPL23,RPL6,PSMD3,PIK3R1,PRPF19,DDRGK1,HNRNPA1,UFL1,COIL,XRCC5,DDX39B,HSPA8,CSNK1A1,EIF4B,BET1,NEK7,STAT1,RABIF,PPP5C,FAU,ARF1,PRMT5,AP2M1,CIRBP,CCT2,HSP90AA1,LDHB,CUL3,MYC,GALE,PRPF31,TOMM40,HNRNPK,THRAP3,TTC4,HSPE1,HUWE1,PTGES3,RPL17,RPS13,MAP1B,RAB1A,HAPSTR1,DNAJC2,TFRC,RAD23B,DDX39A,EEF1A1,PRNP,FZR1,RPS16,TMPO,CDK9,COQ8A,TES,CRBN,RPS2,FAM20C,HDAC6,RPS15,HSPA5,EIF4E,PML,MYH2,BAP1,RPA3,PPM1G,PRDX6,FLCN,METTL14,GRM2,HSP90B1,RPA2,UBE2M,CCND1,RPS14,PSMC4,CFTR,EIF4H,LDHA,RPL22,VIRMA,MYG1,CSTF3,ENO1,FKBPL,RPS3,CCNF,RPS20,EIF3G,SPOP,CHORDC1,UBE2H,ATP1A1,SEC13,AKT1 |
| 1.961e-09 | -20.05 | SLIRP (SRA stem-loop interacting RNA binding protein) | protein interactions | 81892 | 328 | 142 | 19454 | 5460 |
MRPS9,SSBP1,DSTN,FZR1,MRPL50,DBT,DKC1,CDK9,MRPS23,NFKB1,GRSF1,CSNK2A1,EID1,TMEM70,SNRNP70,ESYT1,MAP1B,MRPL52,ATP5PF,PQBP1,MRPS18B,MRPS33,HNRNPK,MRPS18C,MRPL22,FASTKD5,PTGES3,FBP1,ATP5PB,IPO8,MRPL47,NDUFA2,MRPL11,DUSP1,PPIF,AURKAIP1,METTL15,EXOSC8,BCS1L,NDUFS3,GFM2,MRPL49,GAB1,MRPL53,CTNNA1,MRPS28,ACAT1,MRPS21,NDUFAF2,CSK,SUGP1,PYCR2,VAMP5,TUFM,AR,SPOP,MRPS16,RC3H2,IGF2BP1,UBE2H,RBM7,DLAT,GFM1,SQSTM1,NME4,PDHB,MRPL41,AATF,MRPL20,WDR83,MRPL10,NDUFAB1,CFTR,MRPS34,HAUS2,WTAP,MTRES1,RFX5,GATD3,HNRNPL,NDUFS8,EGLN3,CCT7,RMND1,MTRF1,BABAM1,MRPS35,STOML2,MRPL9,NDUFV2,CTNNB1,DDRGK1,RHOG,MRPS26,HSPD1,PREPL,HNRNPA2B1,HINT2,PICK1,MRPS11,FHL3,ETFA,KGD4,ATP5F1D,MRPS17,HNRNPDL,IMMP2L,RAF1,B3GNT2,ETFB,CTNNA2,NDUFS6,PDHA1,MTA2,NDUFA12,TACO1,PNMA1,DLST,CCDC90B,SF3B4,PARL,ESR2,NDUFAF4,MYC,AUH,MTG2,PMPCA,HNRNPAB,PYCR1,MRPS25,HTRA2,DDX39B,NGRN,EXD2,HSCB,NDUFS2,ARHGEF39,ADRB2,MRPS7,NDUFAF3,MRPL12,NDUFA5 |
| 1.975e-09 | -20.04 | PPP1CA (protein phosphatase 1 catalytic subunit alpha) | protein interactions | 5499 | 598 | 234 | 19454 | 5460 |
PPP1R2,USP8,MEF2A,PIAS1,CXXC1,RPA3,DVL2,SIRT7,PRKCB,PPIH,SQSTM1,JUP,CDK1,TOX4,RPLP0,SHOC2,ATG16L1,RPS14,CNP,TMOD3,NDP,VIRMA,CCNF,EIF2AK2,GSK3A,PTEN,STK24,MAPRE1,SEC13,USP14,PPP1CC,NONO,AR,HUWE1,DNAAF10,TUSC3,MDC1,RIGI,PPP1R12A,PQBP1,HSD17B10,ILF2,YTHDF2,LBR,CD2BP2,RPL15,PPP1R18,TOP1,MAPRE2,MDM2,CDK9,CWC15,CAV1,RPL12,WDCP,RB1,TES,MPHOSPH10,BRD3,CLP1,HDAC6,CNTN1,UCHL3,NOP53,CCND3,SKP1,NMRAL1,NUP50,MTX2,PGRMC1,PPP1CB,TUBB,ACTB,MAT2B,GNB1,BAD,SNRPD2,LRRC1,POLR3B,SNRPD1,PPP1R16A,BRCA1,RHOB,PFDN2,BAX,VMP1,PFDN6,CUL3,MCM3,ASF1A,SSRP1,NEK9,ZC3H7A,PCNA,RPS24,SRSF7,CHMP4C,VDR,CSNK1E,TPBG,ASPM,NUP153,INA,RPL7,EGLN3,STX1A,HNRNPD,RB1CC1,RASSF8,BCL2L1,PRDX1,PRPF19,HDAC3,HSPA5,BTBD10,BAP1,PHACTR1,PPP1R26,RPA2,ZNF326,PPP1R8,NEK2,MAFG,KCTD9,PYGM,PPP1R10,PPP1R1B,RPS3,CREB1,PSPC1,CSNK2B,PPP2R5E,SPOP,IGF2BP1,UBE2H,AKT1,SPRED1,SMARCA5,CCNB1,PRKACB,ST13,H3C1,NEDD8,KPNA2,TGFBR2,HNRNPK,PPP1R27,PDRG1,CAPZA1,DDX42,CAPZA2,PHC1,NUPR1,KBTBD4,RPSA,TP53,CDK4,RPAP2,UBXN2B,WBP11,H2AX,RPS16,KCTD3,FZR1,TMPO,KLF9,CDC5L,SYNCRIP,SFRP1,CEBPG,KPNA1,MAP4,PPIL4,CSNK2A1,SRSF2,STAU1,PHB2,DDX39B,SNRPA,SF3B1,HSPA8,HDAC5,AKAP1,EP300,ADSS2,PAK2,PPT1,EIF4B,PIH1D1,MATR3,FBXO22,SNRNP40,PPP1R3C,ESR2,SF3B4,CKB,MYC,CREBBP,SFN,HNRNPC,BTF3,LDB1,CCDC85B,HNRNPF,RUVBL1,RPS4X,TFG,PABPC1,RPAP3,RUVBL2,SCPEP1,SMARCB1,MAX,KIF2A,CCDC181,OSBP,SNRPD3,SNRPA1,CHMP2A,KCTD20,GYS1,SRSF1,WDR82,EED,CSRNP1,IKBKB,AGR2,DDX1,PPP1R11,YWHAB,WWP2,YWHAH,YWHAG,XPO1 |
| 1.986e-09 | -20.04 | ERBB2 (erb-b2 receptor tyrosine kinase 2) | protein interactions | 2064 | 583 | 229 | 19454 | 5460 |
IL6ST,DUSP14,SYK,HSH2D,PAFAH1B1,FRS3,MAP2K1,PEBP1,ITGAV,ADRB2,EEF1G,TIMP1,MYC,MDH1,POLR1B,CKB,S100A11,DOK4,SLA2,DLG4,ZNF189,APEX1,STAT1,TVP23B,TIMM21,LPAR6,SERPINA3,ERRFI1,TOP3B,SH2D5,CRKL,STMN2,EFNB1,PICK1,GPM6B,PABPC1,EPHA4,KRAS,PSMA1,XPO1,SHC3,CTNNB1,PTDSS1,RAB5C,CBL,FAM241B,NCK1,SH2D1A,RAB35,PTK7,HSP90AB1,HNRNPL,RAB1B,EIF2S1,CXCL8,CDC42,HCST,NTPCR,DUSP18,ARL15,FGFR1,SEPTIN6,SLC7A4,POLD2,TICAM2,HSPA5,FTSJ1,CFL1,AKT1,PTPN11,ATP1A1,ATP1B3,SEC61A1,MACROH2A1,TMA7,SRC,CLCN6,GPX1,CDK4,TP53,GRAP2,BIRC5,PSMC3,TFRC,PIK3CA,CDK8,SURF4,ACVR1,NHERF1,NAE1,DDR1,GLCE,MEPCE,DUSP19,FKBP8,NEDD8,AKAP12,SRPRB,L1CAM,TGFBR2,GAPDH,PGAM1,USP2,CDK12,BECN1,SHC1,MCL1,CDK6,ARL4D,ITK,AIP,SSBP1,DOK6,UBE2N,STX6,EPHB6,LCP2,ILVBL,FZR1,GRM1,ASRGL1,CEND1,FKBP1A,SLC25A3,RPRML,VAPB,VAV2,STAP1,HSD17B3,SOCS5,RBM15B,GRB10,CUL3,PIK3R3,KLK5,NTRK3,HSP90AA1,YWHAZ,RHOB,ZMAT2,CD79B,ARF1,JAK2,ACTB,SPCS1,GABARAPL1,ERLIN2,RAF1,DTWD2,PLD3,STIM1,AQP3,JAK1,SLC39A7,FHL3,SLC25A5,HSPD1,CDKN2C,NDUFA4,FLOT1,TRMO,CISH,PIK3R1,PSMD3,AHSA1,HAX1,CDK5RAP3,GJA1,WDR6,MRTO4,CACYBP,CX3CL1,KDELR2,CNP,GABARAPL2,MET,JUP,HSP90B1,RTN4,INPPL1,CYP17A1,NF2,PIK3R2,FBXW7,FBXO7,CSK,STK11,EPHA2,STK24,LGALS8,MSN,CFAP298,STUB1,CCNF,GAB1,SFRP4,TECR,UBB,SH3BGRL,VIRMA,TXN,ZNF622,RHOJ,YES1,MAP2K3,SOCS3,SMAD1,FBP1,PHF23,SELENOK,ERG28,IGF1R,PC,NTRK2,SLC25A10,APBB3,ARF4,CAMK2G,SNAP91,HDAC6,LRRC40,FGR,STYK1,SPP1,HRAS,CAV1,NAT2,PRNP,TOP1 |
| 1.990e-09 | -20.04 | vpu (Vpu) | protein interactions | 155945 | 258 | 117 | 19454 | 5460 |
SKP1,CCR7,HADHA,CD1D,TRIM5,FOS,CXCR4,CD40,RNF7,ATP5PO,IL2RG,CHP1,SELL,STAT1,ATP5F1B,CD3G,BST2,AP2M1,NFKBIA,APOBEC3G,VEGFA,BAX,ICAM1,SLC38A1,FBXW11,FAS,UFD1,FLOT1,AP1M1,ATP5F1D,TNF,OAS1,CD83,SCYL2,HGS,ISG20,IFNGR1,CYB5R1,PPP2R1A,ISG15,JUN,RANBP1,ARFGEF1,ATXN10,XPO5,MAP1LC3A,TSG101,IFIT2,PPP2CB,CD63,DNM2,BCL2L1,TGFB3,TGFB2,VPS4A,IFNB1,IKBKB,CTNNB1,XPO1,CCL11,ICAM2,LAMP2,IFI16,BCL2A1,PIP4P1,B2M,CERS2,RTN4,MAVS,IRF3,CSNK1G3,CCL19,UBAP1,SNAI2,RSAD2,VPS4B,MX1,CXCR3,TRAF1,JUNB,IFNA10,PPP2R5E,SGTA,MSN,CSNK2B,TNFRSF1B,EIF2AK2,AP2A1,CHORDC1,CNTNAP1,CD164,ATF4,PTGES3,SMN1,TGFBR2,TSPAN7,RNF115,NEDD8,IFNA13,ATP5PF,NAE1,SEMA7A,TFRC,TP53,ATP5PB,PREB,CD1C,ATP5PD,MIF,CD4,IFNA2,CD247,APOBEC3F,CD81,SNAP91,CSNK2A1,NFKB1 |
| 2.042e-09 | -20.01 | TKT (transketolase) | protein interactions | 7086 | 314 | 137 | 19454 | 5460 |
ATP5IF1,COX17,HDAC5,EP300,DDX39B,PEBP1,POLA2,LYPLA2,EMC1,STAU1,SRI,NEK7,NDUFAF3,RPE,FABP7,LAP3,ANXA7,PIH1D1,AKR1A1,ACAA2,CYB5R3,ENO2,TAGLN2,AKR1C2,MED17,LGALS3,SNRNP40,CAPG,MYC,CUL3,LDHB,RIT1,CKB,BRCA1,YWHAZ,SCYL2,AHCYL1,ANP32B,SAR1B,WDR19,UFM1,KRAS,VDAC1,SOX2,ISG15,RAF1,ANP32A,EZH2,PLS3,PIR,RAB4A,CHMP4C,IGBP1,FABP5,GLRX,SUMO2,KCTD10,PPIB,IFI16,PRDX1,PDIA3,HSPB1,COTL1,YWHAB,UBE2D1,AK2,AGR2,PGK1,GPX4,SQSTM1,SOD1,RPA3,UGDH,BAP1,YKT6,PMP2,CFTR,SPR,UBE2M,GSTP1,RPA2,LDHAL6B,HSP90B1,PITPNB,ABHD14B,UBE2I,TRIM24,MSN,CCNF,ZNF330,ENO1,TUBA1B,VIRMA,NDN,LDHA,KCTD9,SNX3,RUNX1,FBXO7,CFL1,AR,TRIM32,ATP1A1,UBE2H,CALU,GLOD4,HAPSTR1,IDH1,TAGLN3,HSD17B10,HINT1,MAP1B,PTGES3,NEDD8,HSPE1,RPIA,H2AX,TP53,SOD2,PPME1,TBC1D4,TFCP2,DSTN,TES,AKR1B1,CD274,ESD,MIF,HDAC6,GLO1,TPM3,GAPDH,CALR,PGAM1,SMG8,NME2,H2AC4 |
| 2.053e-09 | -20.00 | RETREG3 (reticulophagy regulator family member 3) | protein interactions | 162427 | 209 | 99 | 19454 | 5460 |
ATP5F1B,REEP4,SCN2B,LMBR1L,FAXDC2,TMEM100,GPR17,CMTM6,STAP1,STX7,CERS6,JAGN1,TSPAN15,RABAC1,SLC35F2,TMEM203,VAPB,SMCO4,SIGMAR1,CMTM7,BET1,AGTRAP,GOSR2,YIPF5,OTULINL,SEC22A,CCDC167,SEC62,VAMP1,TSPO2,TMEM237,RMND1,CD63,MAP1LC3A,STX5,FAM241B,ARHGAP5,TMEM208,TSPAN10,FAM241A,TMEM60,UBE2A,PLPP6,PLSCR1,CYB5B,GABARAPL1,TMEM176A,CD47,TECR,VAMP3,CDIPT,SCAMP2,SYNGR1,ODR4,SAYSD1,TYROBP,REEP6,VAMP5,CSGALNACT2,HMOX2,CERS2,LPAR1,TSPAN5,TMEM254,VIPR1,DERL1,RTN4,TMEM243,RPA2,SAMM50,HCST,PLP2,GABARAPL2,ARL6IP5,ANKRD46,DERL2,TNFSF18,GNPTG,FUNDC2,MSMO1,TMEM42,P2RY1,TMEM11,MOV10,ORMDL3,TF,FKBP8,STX8,RUSF1,ATP5PF,TCEA2,ERG28,TSPAN17,TMEM31,ARPC3,ATP5PB,YIPF4,UBIAD1,NRM |
| 2.059e-09 | -20.00 | FAS (Fas cell surface death receptor) | protein interactions | 355 | 351 | 150 | 19454 | 5460 |
TRAFD1,ERG28,FAF1,CAPZA1,PTGES3,KPNA2,NSMCE3,PSMA5,LBR,UBXN2B,EEF1A1,RAP1A,TP53,KRIT1,IFT57,RB1,ADD1,SSU72,SRPRA,AIP,CAV1,MYL12A,FAM118B,GTF2E1,STYK1,TSNAX,DNAJC7,KPNA1,ESYT1,ECD,ARL2BP,SQSTM1,LSM12,PML,UGDH,PPM1G,RPA3,HSPA5,DESI1,NPM3,CERS2,CREBZF,XBP1,COMMD3,TPT1,ACBD6,SUMO1,TFIP11,PRKCA,CDR2,MET,EPHX1,STX17,ODR4,MSN,UBE2I,POP7,EIF2AK2,CCNF,SRC,SEC63,VKORC1L1,DHRS13,YES1,CD47,RHOBTB3,KPNA6,DNAJC5,CFL1,RETSAT,HSPA14,NDUFB10,MAPRE1,PEA15,PTTG1,BICD2,BAG2,PCNA,ATP6V0B,RUVBL2,PICK1,MAEA,GADD45A,RINT1,SSRP1,ASF1A,TNF,TRIM26,CCS,FAF2,OTUD6B,FASLG,CYB5B,SMARCB1,POLR2C,PRKAG1,CFAP36,TUBB4B,CYB5A,KRT8,RAB35,CETN2,CACYBP,AGK,SNX1,DDRGK1,WDR11,FEM1B,CTNNB1,MAP1S,PIK3R1,UBXN6,LRRC57,TNFSF13,EP300,NUBP2,IMPACT,SKP1,CCND3,GINS3,UFL1,TIMM29,EHD1,PGRMC1,NUP62,ATP6V1C1,TRMT112,CSNK1A1,MYL6,SEC61B,PELO,EIF3K,FAIM,PNMA1,FAM91A1,RPL10,USP5,CHP1,LRIF1,RBBP4,TUBB,TCAP,HNRNPC,CUL3,VEZT,CRMP1,FAS,COMMD9,COX16,POMP |
| 2.062e-09 | -20.00 | FASN (fatty acid synthase) | protein interactions | 2194 | 1033 | 375 | 19454 | 5460 |
UBP1,HACD3,H2AZ1,CAV1,ZBTB2,HDAC6,BAK1,TLE1,DNAJC7,HSD17B10,PC,NSDHL,OLA1,ADIPOQ,CAMK2G,PCED1B,MAP1LC3B,YTHDF2,PHF23,ILF2,PPME1,GABPB1,DMAP1,PTEN,EIF4A3,INPP5K,SEC63,TECR,RAB14,ZNF622,USP14,CSK,CDC16,TADA1,TADA3,TEX19,SQSTM1,MTDH,SYVN1,SIRT7,SLC39A9,MBD3,SGF29,GTF2I,EIF3J,HACD2,TPT1,CCND1,MYLIP,ZNF574,LMNA,JUP,TSG101,PHB1,CGGBP1,TRA2A,MARCHF5,PSMD3,PRPF19,ZBED4,AHSA1,PSMD10,ZC3H7A,CCDC32,AKT2,MORC2,EIF2D,MCM6,ETFA,LGR4,GTF2E2,GFPT1,ASPM,GFI1,CYB5B,NGB,EZH2,AP2M1,EIF3K,PELO,GGPS1,RPL35,RNF40,CUL2,CUL3,SCG3,USP13,NDUFB7,SP1,MCM8,TAFAZZIN,CRY1,THOC3,FBXL4,COIL,LCMT1,TRAPPC3,CD274,CDC5L,TMPO,FCHO2,CSNK2A1,KARS1,SLC35A1,SLC16A1,NOSIP,SLC6A8,ZMYM4,CDK4,NAA35,UBL4A,PSMC3,SESN2,MAD2L1BP,TMEM165,TFCP2,SGTA,UBN1,DUSP3,SMURF1,ADRM1,PPAT,KCTD9,SPMIP10,SUB1,PTPN11,CEP85,MAT2A,ATP1A1,LSM6,SPOP,RNF113A,HCFC2,HSPA5,MARS1,POLR1H,KDM1A,CFTR,ING5,DNAJC24,ACACA,UBE2M,VPS54,HEXIM1,CYB5R4,RPRD1B,RPA2,EED,MPDU1,DIO1,ELK1,TRIR,MEAF6,CCL11,GSTM3,TAX1BP3,AGR2,FBXO11,PABPC1,CCT8,RERE,HNRNPDL,VDAC1,ZNF609,ISG15,PPIL3,TOP3B,PHF12,USP38,FRZB,PSMD6,PSMD4,CYP27A1,GTPBP2,LRRC20,EP300,HDAC5,HSPA8,DPH6,STAU1,RER1,EMC1,NEK7,FBXO42,PIH1D1,NCOA5,LDLR,PTPN1,AIG1,NCBP2,CDK9,DERL2,DCUN1D1,SUV39H1,ATP5MG,LAMTOR2,TGIF2,SFXN1,RAB1A,VPS16,FASTKD5,PAGR1,MRPS18C,TTC4,NOC4L,VRK1,HUWE1,ANAPC11,FAM169A,TRAPPC13,ODR4,CTNNA1,CCNF,PDCD5,WDR83OS,VIRMA,NDN,FBXO7,TAF5L,HSPA14,BAHD1,TCEA1,KICS2,RPA3,INPPL1,PIK3R2,SLC7A1,IRF7,NF2,KLF12,CCNA2,RABL3,RARS1,RPLP2,DHX15,EGLN3,SRSF10,HYPK,DNAJB9,HNRNPA1,SLC20A1,TMEM30A,CDK5RAP3,TMEM147,AHCYL1,SAR1B,RAD21,ASF1A,PPP2R1A,RAF1,DPH5,ITGB5,PRKAG1,CHMP4C,NME1,VPS72,UBE2V2,MAT2B,RPF1,BMP1,HTRA2,ILK,RPS5,HSP90AA1,BRCA1,SENP8,CCND3,PAFAH1B2,UCHL3,DET1,RRAGA,MAPKAPK5,OR4K1,CDK6,GATAD1,UBE2G2,MRPS9,SLC38A2,MBD5,FZR1,TMED9,CAND1,TPM3,EDC3,USP3,USP2,MAP4,FITM2,SHC1,TRAPPC2L,PSME1,MAP1B,EDEM2,INSIG2,TP53,MVD,KBTBD4,CDK8,CBX3,PIK3CA,PPP2R5E,RNF187,DYRK1A,ACP2,UBA3,ARL6IP6,ATF4,NUDT4,AKT1,RAB2A,RBM7,UBE2H,DTL,EXOSC1,ENDOD1,IRF3,PML,BAP1,UGP2,OR13C8,HIKESHI,SYS1,WDR82,RBM5,RPRD1A,HSP90AB1,SUMO2,COMMD6,RPS10,DDRGK1,XPO1,CPEB1,PTDSS1,RAB5C,WWP2,CNOT2,INPP4A,MAGOH,TRIM21,CDK5,EWSR1,SCPEP1,RAB18,CBLL1,SLC35A2,HNRNPF,GCLC,MOB3C,RPS23,PDHA1,PTRH2,PLS3,DLST,LMBR1L,IRF2,PAPSS2,VDAC2,ESR2,TAX1BP1,MATR3,SNRPB,BTF3,PSMA4,LDHB,MYC,COP1,OAZ1,BOLA3,PEBP1,DDX39B,UFL1,MTF1,PTAR1,EIF4B,PPT1 |
| 2.096e-09 | -19.98 | MRPL18 (mitochondrial ribosomal protein L18) | protein interactions | 29074 | 193 | 93 | 19454 | 5460 |
MRPL12,RPL27A,MRPS18A,MRPL34,RMND5B,NGRN,RANBP10,MRPS7,TRA2B,HSCB,MRPL57,MRPL16,MYC,AUH,NOP16,PMPCA,H1-1,HTRA2,MRPS25,MRPL13,TACO1,KBTBD6,RPL19,RPL10,MRPL23,RPL35,DLG3,RPS11,HINT2,MKLN1,SRSF7,MAEA,UTP25,H1-6,HNRNPA1,MRPL9,TRA2A,MTRF1,MRPS35,MRPS26,ARMC8,RHOG,MRPL18,FAHD1,GATD3,SRSF10,MRPL10,RBMS2,ZNF574,RPL26L1,MTRES1,GFM1,GID4,GID8,NHP2,MRPL20,MRPL17,MRPL40,MRPL41,TUFM,ZMYND19,YPEL5,UBE2H,MRPL53,VIRMA,RPL13A,MRPL11,MRPL47,MRPL33,MRPL51,TAF2,MRPL49,RPL23A,RPL3,MRPL52,MRPL22,RPL17,MRPS33,GRSF1,MOV10,SMAD4,CHCHD1,SNRNP70,SSBP1,MRPS9,AIFM1,ALYREF,MALSU1,DBT,MRPL24,SLC25A12,FZR1,MRPL50 |
| 2.104e-09 | -19.98 | LDHB (lactate dehydrogenase B) | protein interactions | 3945 | 286 | 127 | 19454 | 5460 |
VIRMA,SMURF1,IDE,EIF4H,NDN,LDHA,KCTD9,PTEN,FAM210A,ENO1,PAFAH1B3,CCNF,SORD,UBE2H,OAT,TRIM23,SPOP,USP14,CFL1,CFL2,CTSD,PGK1,PML,BAP1,SOD1,RPA3,UBE2M,HEXIM1,METTL14,RPA2,SDCBP,CFTR,GABRA1,ATG16L1,G6PD,MIF,PRNP,FZR1,LDLR,DSTN,EEF1AKMT3,UBE2N,SSBP1,NME2,COPS5,HDAC6,ARF4,HUWE1,GARRE1,FAF1,RAB1A,GNAI3,RNF8,PPME1,NHERF1,TFCP2,GINS4,PGM1,UBE2V1,H2AX,TP53,UBL4A,TENT5C,ANAPC2,DLST,ARF1,MDH1,VMP1,YWHAZ,BRCA1,CKB,RHEB,LDHB,HNRNPAB,CUL3,MYC,PHB2,PAFAH1B2,STAU1,UFL1,PRCP,NUP50,EP300,RAB5A,NMRAL1,HSPA8,NANP,PIH1D1,CKS2,CNDP2,PPT1,PAK2,PSMB7,PPIA,RAB1B,FAHD1,PHB1,YWHAB,ARMC8,DCAF11,AHSA1,UBFD1,AGR2,DDRGK1,CTNNB1,YWHAG,RAB5C,SAR1B,FLOT1,FKBP2,ETFA,G3BP1,EWSR1,HNRNPA2B1,MOB3C,PDHA1,NGB,RAB4A,CHMP4C,EZH2,MSX2,GFPT1,ISG15,SOX2,HEXA,CKS1B,RAF1 |
| 2.185e-09 | -19.94 | SCFD1 (sec1 family domain containing 1) | protein interactions | 23256 | 220 | 103 | 19454 | 5460 |
RAB9A,DERL1,SYVN1,BAP1,RPA3,MRPL40,NAPG,YKT6,ST7,CDC42,MPV17,SEC22B,HEXIM1,FGFR1,SSR1,USE1,LMNA,RPA2,STX10,SGTA,SEC63,VIRMA,COPE,GORASP2,VAMP5,NAPA,IGF1R,SNAP23,STX18,STX8,RAB1A,FKBP8,RAB3B,ACTR1A,SNAP29,MRPL49,ILF2,TFRC,RAC2,HSD17B11,PTPN1,CAV1,TMPO,STX6,MIF,DNAJC1,VTI1B,LAMP3,EMC4,SLC25A46,MOV10,ESYT1,BET1L,RAB5A,APPBP2,STX7,PXMP2,STAU1,RER1,GOSR1,EMC1,SEC62,YIPF5,OTULINL,RND2,BET1,PGRMC1,GOSR2,SLC25A3,VAPB,MRPL13,SEC61B,RMDN3,DLST,LMBR1L,APEX1,ATP6AP2,ESR2,STX16,RAB11A,MYC,NTRK3,RHOB,LMNB1,TMT1A,RINT1,SACM1L,KRAS,DNAJC25,SOX2,PTRH2,STIM1,VAMP2,STX5,GJA1,RAB35,EGLN3,RAB1B,MRPL9,RAB5C,LAMP2,RB1CC1,RHOG |
| 2.290e-09 | -19.89 | SNX3 (sorting nexin 3) | protein interactions | 8724 | 180 | 88 | 19454 | 5460 |
TFG,AHCYL1,KRAS,VPS26B,HGS,RAB4A,PIR,PLS3,PPIL3,RBM12,FHIP1B,WIF1,PPIA,SNX1,SNX2,HEBP1,IGBP1,TBC1D5,YWHAG,RAB5C,VPS26A,CRIP1,LAMP2,UBXN6,ATG9A,STX7,RAB5A,AKR1A1,HSD17B6,RFXANK,BET1,DYNLL1,SIAH1,MANSC1,TAGLN2,AKR1C2,SCNM1,BRCA1,CYP1A1,LAMTOR1,CAPG,TMEM183A,CAV3,RAB11A,STX11,SRPRB,TAGLN3,ZC3H11A,TFRC,NDUFA2,CENPM,CAV1,MBD5,DERL2,ARF6,MTAP,SEC23A,ARL4D,PSMB1,EEF1AKMT3,RPRM,SSBP1,HRAS,LAMP3,DPP4,RAB9A,PPM1G,RHOU,PITPNA,ARL15,STX17,SNRNP27,SETD3,ATG16L1,UBE2L3,RHOJ,SLC1A1,SNX12,EIF4A3,OPTN,MRPL53,SNX5,GLOD4,ANO3,ARL6IP6,GJB2,RAB2A,SUGP1 |
| 2.315e-09 | -19.88 | POLR1D (RNA polymerase I and III subunit D) | protein interactions | 51082 | 136 | 71 | 19454 | 5460 |
TMEM184C,HAX1,MED4,KARS1,PGAM1,POLR3GL,POLR3F,NOB1,MAPRE2,POLR2I,EGLN3,CACYBP,HSP90AB1,DHX15,NOP9,ASNSD1,RPRD1A,POLR2L,CDK8,SPSB3,POLR2C,POLR2G,POLR2D,CRKL,TRMT1L,TP53,E2F4,RPAP2,TUBA1A,RUVBL1,DNAAF10,KPNA2,PDRG1,GTF3C3,ANP32B,IMMP2L,TFPT,DNAJB4,RUVBL2,RPAP3,PFDN2,OSGEP,POLR1B,DNAJB6,MAF1,PFDN6,HTRA2,TMEM38B,MYC,RRN3,POLR2B,DEK,ATL1,NFKBIB,RSRC1,SYBU,POLR3B,POLR2F,POLR3H,RPRD1B,PICALM,PIH1D1,TPT1,CDC42,MRPL12,STAU1,MBD3,POLR1H,CDC42EP4,INPPL1,DDIT3 |
| 2.316e-09 | -19.88 | STOM (stomatin) | protein interactions | 2040 | 323 | 140 | 19454 | 5460 |
CUL2,FAXDC2,LAMTOR1,RHOB,SF3B4,LMBR1L,CYB5R3,ESR2,TNPO3,RND2,CHST1,CTXN3,TOMM22,VAPB,SMCO4,ATP5PO,MMP14,SIGMAR1,TMEM185A,EP300,TMEM203,TMEM106B,EMC1,UFL1,ADRB2,PHB2,XPO1,LAMP2,TMEM208,PMP22,STOML2,PTDSS1,CBL,RHOG,ZCCHC9,AGR2,GJA1,XPO5,ATP6V1A,SPRED2,PHB1,TSPO2,ERLIN1,LANCL1,NUP35,ASIC1,RHOH,ATXN10,SNRPA1,SOX2,FAF2,YIPF3,ERLIN2,RAF1,CYB5B,TMEM14B,GPM6B,RUVBL2,ATP6V0B,GPAA1,CCT8,TMT1A,SAR1B,RNF26,TMEM60,TRIM26,TNF,KRAS,VDAC1,RUVBL1,ELOVL3,HMOX2,SLC35B4,RAB2A,FGFR1OP2,SUGP1,CSK,CCNB1,FOXA3,ATP1B3,ENDOD1,CCNF,UQCRC2,CLRN2,TECR,RPL13A,RHOJ,YES1,TMEM106A,UQCRC1,CDC42,RABL3,RPA2,COX6C,STOM,GRM2,TMEM254,RHOU,ORMDL1,SLC25A51,LPAR1,HDAC6,HM13,COPS5,EI24,AGPAT1,SLC2A1,ASIC2,LHFPL4,STARD3NL,RAC2,PTPN1,RPRM,SSMEM1,ATP5PD,FUNDC2,STX6,TMPO,CAV1,AIG1,DNAJC1,ARF6,PRNP,CGAS,FBP1,ATP5PB,MTCH2,SELENOK,IPO8,SLC25A24,SURF4,ERG28,PGA4,SFXN1,ARF4,SFT2D2,TOLLIP,GPR37L1,GIMAP2,CSE1L |
| 2.328e-09 | -19.88 | NDUFV1 (NADH:ubiquinone oxidoreductase core subunit V1) | protein interactions | 4723 | 278 | 124 | 19454 | 5460 |
ARMCX3,STXBP1,TIMM29,TOMM22,NOTCH2,EMC1,HSCB,NDUFS2,OXCT1,PHB2,ADRB2,HADHA,NGRN,EXD2,HTRA2,TOMM40,PCCB,FMC1,NDUFB6,COX6B1,MTG2,AUH,NDUFB7,PMPCA,PARL,ESR2,ATP5F1B,ACTB,VDAC2,TACO1,LMBR1L,MTG1,CCDC90B,NDUFA12,NDUFS6,PDHA1,EEF2,E2F4,IMMP2L,EMC8,VDAC1,HINT2,EWSR1,HSPD1,NDUFA4,MRPS26,NDUFB8,RHOG,PEDS1,NDUFV2,CTNNB1,MTRF1,NDUFS8,UQCRH,COX14,RMND1,CORO1C,ATP6V1A,GATD3,PHB1,MTRES1,CYC1,RPA2,PAK5,HSP90B1,CDC42,UQCRC1,TIMMDC1,CRYZ,PDHB,SLC25A51,NDUFC2,GFM1,RPA3,ATP1A1,DNAJC19,TUFM,HMOX2,NDUFB10,RNASET2,UQCRQ,PNP,MGST3,OPTN,UQCRC2,GFM2,NDUFS3,AURKAIP1,METTL15,ATP5PB,RRM1,NDUFA2,MTCH2,MRPL11,FASTKD5,PDE2A,MPST,DNAJC30,EMC2,TCOF1,SFXN1,DNAJC4,SMAD4,POR,TMEM70,PSMD7,CHCHD1,COPS5,ATP1B1,GRSF1,LAMTOR2,COX5A,EMC4,MYL12A,SLC25A12,MIF,NDUFA1,RAC2,AIFM1,SSBP1,SDHB,COMT,COX4I1,NDUFB4 |
| 2.334e-09 | -19.88 | BSG (basigin (Ok blood group)) | protein interactions | 682 | 608 | 237 | 19454 | 5460 |
PEBP1,HSPA8,RAB5A,EMC1,UFL1,ADRB2,OXCT1,TOMM22,BET1,SEC62,DHRS4,CTBP1,PPT1,NCOA5,LMBR1L,FBXO22,CBX5,APEX1,MYC,LAMTOR1,RINT1,EWSR1,MYO1B,KRAS,VDAC1,PAK6,RAB18,POLDIP3,ARFGEF1,TUBA1A,NCSTN,TNPO2,TUBB4B,PDHA1,NDUFA12,RND3,HGS,MOB3C,RAB35,FUBP3,HEBP1,RAB1B,RHOH,LANCL1,HSP90AB1,LAMP2,ASB1,RAB5C,DDRGK1,EXOC1,ARMC8,RAB9A,AIF1L,HSPA5,CDC42,CFTR,RPA2,UBE2M,GCFC2,PITPNB,SEC61A1,INTS12,PTPMT1,NDUFAF2,RAB2A,DNAJC5,NCAPG2,ATP1B3,OAT,CALU,SORD,MAP1B,ATP2B4,SLC25A11,SLC16A1,MAN1A2,RBCK1,RAB3B,CSE1L,RDH11,FKBP8,PREB,FAM162A,RAP1A,CHRM3,IPO8,METTL15,TFRC,PIK3CA,EXOC3,GNAI3,FURIN,SLC25A24,UBE2G2,DSTN,GNPAT,RAC2,TMED9,CAND1,STX6,ILVBL,LMAN1,DPP4,KARS1,API5,CDK12,NMRAL1,PMAIP1,NPTN,ATAD1,GPC1,SRM,STX7,PGRMC1,RFXANK,RND2,RAB6A,MYL6,GNG12,RMDN3,SEC61B,MB21D2,LGALS3,TUBB,MAD2L1,GNB1,TNPO3,CLIC4,PARL,VEZT,RAB11A,CUL3,SLC16A4,RHOB,NTRK3,HSP90AA1,VMP1,SLC25A5,NDUFA4,BCKDK,COX8A,TMED7,SACM1L,SSRP1,MARCKSL1,ACTN4,ERLIN2,DSTYK,RPN1,GDI2,CHMP4C,AP2S1,TMEM14B,CYB5B,DNM2,PHB1,GJA1,KRT8,MPP1,ATXN10,EGLN3,PPIA,DIRAS3,NUP35,OS9,STOML2,RHOG,DDX23,CDK5RAP3,TRAF6,RHOU,RPA3,SYVN1,RTN4,PDHB,CCR4,ARHGAP1,SEC22B,SLC35E1,COMMD3,CNP,CDK7,HSP90B1,TTI2,STUB1,METAP2,TUBA1B,SFXN2,RAB14,MGST3,SNX3,RHOJ,YES1,UQCRQ,DEK,VIRMA,GNAI2,RHOBTB3,USP14,NRP1,XPOT,NAPA,AP2A1,MAPRE1,SLC25A10,RAB1A,SFXN1,HAPSTR1,RING1,HSD17B10,FASTKD5,ARF4,RNASEL,RIGI,PTGES3,CMPK1,CCDC47,YTHDF2,NDUFA2,CTDSP2,AGPAT5,VAC14,DHRS7B,HRAS,DECR2,ARF6,COG1,FAM118B,NOP9,ZBTB2,CAV1,HM13,LAMP3,GLO1,CRBN,EXOC2,STYK1 |
| 2.341e-09 | -19.87 | MYBBP1A (MYB binding protein 1a) | protein interactions | 10514 | 418 | 173 | 19454 | 5460 |
RPL7,RPLP2,HP1BP3,RPL8,MYEF2,DDX23,RPS27A,G3BP1,PCNA,COX8A,RPS24,FGF3,RPS11,EZH2,CHMP4C,MAK16,JUN,LGR4,RAF1,E2F4,RPL35,RPF1,RPL7L1,RPL37A,ZNF22,LMNB1,BRCA1,ZNF668,NOP16,CUL3,TMED4,TMED3,NOP53,APOBEC3C,ZBTB2,NOP9,KRR1,RCHY1,HDAC6,APOBEC3F,GRSF1,RPS13,RIGI,SMN1,PAK1IP1,RPL23A,HAPSTR1,ILF2,TAF1D,EEF1A1,AURKAIP1,RPL15,NDN,RPL13A,PRKRA,PTEN,UBE2I,CCNF,TNFRSF1B,RPL26,AR,PPP1CC,BRIX1,DGCR8,NPM3,FBXW7,RPL4,MTDH,SOD1,RPA3,SIRT7,RPL26L1,RPLP0,MACROH2A2,LMNA,METTL14,RPS14,ATG16L1,CCND1,RPS10,LYAR,EED,AGR2,DDRGK1,CTNNB1,BAZ1B,IFI16,RIOX2,WWP2,RPL6,RPL28,KRAS,H1-6,RPL31,RPL18,RPS23,GLE1,DCAF8L2,NCSTN,ISG15,MAGEB10,RPL10,MATR3,LMBR1L,TRIM44,NSA2,H1-1,H1-10,FTSJ3,BTF3,MYC,TMED5,HNRNPC,HNRNPA0,UFL1,STAU1,HSPA8,EP300,MTF1,TMPO,MBD5,DKC1,SURF6,CDC5L,FZR1,DNAJC1,CAND1,RPS16,ARL4D,RPL32,RPS2,RPL10A,SNRNP70,H2AC4,COPS5,ELOC,CMSS1,PLEKHO1,RPL17,H3C1,RPL3,SNIP1,HBP1,NUPR1,DNAJC2,RBM34,IK,TP53,RSL24D1,SRPK2,FGFBP1,RPS3,PSPC1,ZNF330,ZBTB38,RRP7A,UBE2H,MECP2,RC3H2,GORASP2,SMARCA5,RPF2,RPL7A,RPS15,RNF113A,RPL27,BAP1,NLE1,PML,ZNF770,RPA2,AGO1,CDC42 |
| 2.342e-09 | -19.87 | OPA1 (OPA1 mitochondrial dynamin like GTPase) | protein interactions | 4976 | 196 | 94 | 19454 | 5460 |
CSTPP1,EEF2,IMMP2L,USP30,KRAS,HAX1,SKIC8,P2RY10,ATG7,NDC80,MARCHF5,FAM174A,NDUFS8,EGLN3,PHB1,CSNK1A1,PIH1D1,MED23,DUSP22,TIMM29,INSYN2A,EHD1,NPY2R,PRDX3,TIMM13,BET1,MTX2,STAU1,PHB2,NPTN,AKAP1,EP300,HSPA8,HTRA2,LMNB1,RHOB,TAFAZZIN,LAMTOR1,BTF3,TOMM40,CUL3,GPR17,MYC,COX6B1,PARL,ESR2,CHCHD3,FBXO22,S100A6,LMBR1L,SCN2B,APOO,FKBP8,CLPB,HAPSTR1,SFXN1,TLR4,TPM3,SLC25A46,COX5A,SLC25A12,PLGRKT,CDK9,TOMM70,CAND1,ARF6,COX4I1,SMAD3,AIFM1,PTPN1,SAMM50,SLC25A51,FBXW7,YKT6,RNF113A,MAVS,DERL1,PML,GID8,MME,RPA3,UBE2H,SMAD2,POU1F1,CHCHD4,CISD1,NPTX1,VIRMA,DYRK1A,ROMO1,DAPK3,CHCHD6,CCNF,OPTN |
| 2.342e-09 | -19.87 | DNAJC19 (DnaJ heat shock protein family (Hsp40) member C19) | protein interactions | 131118 | 196 | 94 | 19454 | 5460 |
NDUFAF4,MAD2L2,RANBP6,MRPL13,MCPH1,DLST,TACO1,MRPS25,RPS29,MRPS7,CMAS,PHB2,SLC15A1,HNRNPA0,NDUFS2,TIMM17A,HADHA,TSPAN15,NDUFA5,MRPL12,NDUFAF3,PGRMC1,TMEM231,NDUFS8,RPL7,RPLP2,PHB1,FBXO31,RPL8,DICER1,MRPS26,HAX1,RHOG,DDRGK1,HNRNPA1,NDUFV2,STOML2,MRPS35,RPL6,IMMP2L,ANP32B,FLOT1,MRPS17,ETFA,CHCHD2,NDUFA4,RPL18,NDUFA12,AQP3,NDUFS6,RPN1,ETFB,SLC1A1,RPS12,PTPMT1,TRIM24,MRPS28,MRPL53,UBE2H,MRPS16,PYCR2,RPL7A,NDUFAF2,MRPL20,HSPA5,SLC5A6,TSPAN5,RPL4,NME4,GHRL,TWNK,RPL27,MAIP1,PPM1G,RPA3,RPLP0,RPA2,MRPS34,MRPS23,DUOXA2,MRPL50,FZR1,SRP14,MRPS9,SSBP1,OSBPL8,MRPL22,PDE12,MRPS18B,MRPL49,NDUFS3,RPL15,NDUFA2,CCDC47 |
| 2.384e-09 | -19.85 | KLF16 (KLF transcription factor 16) | protein interactions | 83855 | 421 | 174 | 19454 | 5460 |
HUWE1,NOC4L,RPS13,SMN1,EIF3E,RAB1A,SFXN1,ILF2,YTHDF2,ING1,LBR,ATP5PD,MRPS23,AIFM1,CTDSPL2,TFE3,HACD3,MYBL2,PSMB1,NME2,PSMD7,FOXP1,GLO1,GTF2I,BRIX1,MRPS34,COX6C,HSP90B1,HNRNPH3,RPL26L1,PSMC4,SEC22B,UQCRC1,RPL13A,TECR,ZNF507,GANAB,SEC13,RPL26,RACGAP1,BPGM,G3BP1,ZBTB14,PSMD12,GTF3C3,PCGF6,RAD21,PCNA,RPN1,NME1,RPS11,RAF1,BUD23,CCAR2,AGK,EGLN3,PHB1,PSMB4,PSMB5,HP1BP3,HNRNPD,MRPS26,PRPF19,CLPX,MRPS35,EIF3D,NOP53,YTHDF1,PSMC1,G3BP2,PSMB7,ATP5PO,MFAP1,NDUFA5,PGRMC1,TIMM13,PRDX3,PRRC2A,GNG12,CYB5R3,VPS72,RPL37A,RPS5,NOP16,PSMA5,CSE1L,NOSIP,MRPS18B,TFRC,RBM34,PSMC3,ATP5PB,ESS2,ZMYM3,TMED9,BRMS1L,MYL12A,SURF6,MRPS9,SSBP1,STT3A,SYNCRIP,COX4I1,RPL32,GATAD1,SMCHD1,AKAP8L,COX5A,RPS15,BAP1,TWNK,RPA2,E2F6,ZNF770,ADRM1,GABPA,UQCRC2,ZBTB33,ING2,QSER1,PSMC5,INTS12,EIF3G,CHCHD4,IGF2BP1,CCDC174,ATP1A1,ZBTB38,PSMB2,FOXA3,RPS17,PSMA2,PSMA1,KRAS,VDAC1,RPL31,LSM14A,RUVBL2,MAX,RANBP1,ELF1,RPS10,SIN3A,ZHX1,BAZ1B,PHB2,GNB4,MRPS7,SLU7,EP300,TRMT112,PSMB3,MRPL12,PSMD4,PSMD6,LRIF1,PSMB6,RPL10,KBTBD6,PHF12,VDAC2,ATXN1L,CKB,FTSJ3,H1-10,PSMD14,ZMPSTE24,MYC,COX6B1,PSMA4,RPL39,PSMD1,KANSL3,BRMS1 |
| 2.386e-09 | -19.85 | CD2BP2 (CD2 cytoplasmic tail binding protein 2) | protein interactions | 10421 | 223 | 104 | 19454 | 5460 |
HSD17B10,EMC2,THRAP3,TSSC4,SNRPG,RIGI,CHRM3,NAA35,WBP11,CD2BP2,DDX42,GINS4,NAA30,FZR1,CD2,CDC5L,RBM42,MOV10,CSNK2A1,ECD,SNRNP70,KIAA1143,TUBG1,KPNA1,NLE1,PRPF4,BANF1,RPA3,DDX46,PPIH,RBM22,CCND1,SNRPN,SF3A1,TXNL4A,SNRNP27,PLP2,LSM2,RPA2,LMNA,HEXIM1,UBE2M,TFIP11,GCFC2,CCNF,PSPC1,SGTA,TRAF7,CMBL,VIRMA,SH3BGRL,PPP1CC,NONO,KPNA6,UBE2H,PRPSAP1,EWSR1,SSRP1,AHCYL1,SRSF4,DHX38,E2F4,TOP3B,RAF1,SART3,SNRPE,SRSF1,GJA1,SNRPD3,SNRPA1,DHX15,EGLN3,PRPF19,DDX23,COTL1,SLU7,SNRPA,DDX5,SF3B1,STAU1,GINS3,PPP1CB,USP39,TRAPPC6A,MFAP1,RSRC1,S100A6,SNRPD2,AP2M1,SF3B4,SNRPD1,SMU1,SNRNP40,EIF4A2,ESR2,ERH,SNRPB2,UBE2V2,CUL3,MYC,SNRPB,PRPF31,PSMD14,POMP |
| 2.413e-09 | -19.84 | NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2) | protein interactions | 4720 | 267 | 120 | 19454 | 5460 |
NDUFAF4,ESR2,PARL,MAD2L2,ATP5F1B,LMBR1L,TACO1,VDAC2,IRF2,CCDC90B,MTG1,HTRA2,CGRRF1,BRCA1,TOMM40,PCCB,AUH,MYC,MTG2,PMPCA,CUL3,NT5C3A,EMC1,HSCB,ADRB2,PHB2,HSPA8,HADHA,NGRN,EXD2,PPT1,DHRS4,OTULINL,TIMM29,NDUFAF3,KCND3,TOMM22,EGLN3,NDUFS8,RMND1,COX14,CORO1C,GATD3,ATP6V1A,PHB1,MRPS26,POU5F1,ARMC8,RHOG,NDUFV2,MTRF1,IMMP2L,VDAC1,HINT2,MKLN1,COX8A,NDUFB5,HSPD1,SDHC,NDUFA4,NDUFA12,PDHA1,NDUFS6,FAF2,UQCRQ,MRPS21,UQCRC2,CCNF,MARCHF3,ATP1A1,DNAJC19,UBE2H,BFAR,TUFM,HMOX2,CRYZ,PDHB,SLC25A51,SYVN1,SQSTM1,GFM1,DLAT,MAIP1,RPA3,MTRES1,CYC1,COX6C,RPA2,HSP90B1,UQCRC1,TIMMDC1,MYL12A,FZR1,LDLR,NDUFA1,SSBP1,AIFM1,COX4I1,TNFRSF14,CHCHD1,TMEM70,COPS5,CALR,GRSF1,MOV10,FASTKD5,RIGI,DNAJC30,EMC2,IGF1R,SFXN1,GFM2,NDUFS3,EGR2,APOO,AURKAIP1,METTL15,ATP5PB,MRPL11,MTCH2 |
| 2.416e-09 | -19.84 | RAB | prosite domains | PS51419 | 95 | 54 | 12186 | 3388 |
MRAS,RAP1B,RAB5A,RAB3B,RAB23,RAB28,RAB3A,RAB30,RAB11B,RAB27A,NKIRAS1,RAB32,RAB19,AGAP2,RND3,RAB29,RAB14,RAB1B,RAB33B,RAB40AL,RAP1A,RAB13,RAB11A,RAB3D,RAB3C,RAN,RAB31,RAB6B,RAB5C,NKIRAS2,KRAS,RAB33A,RAB39B,RAB9B,AGAP1,RAB22A,HRAS,RAB9A,RAB4A,RAB8B,RAB1A,RAP2C,RHEB,RAB35,RAB6A,RAB18,DNAJC27,RHOH,RAB2A,RAB37,RABL3,RHOJ,RABL2B,RHOG |
| 2.425e-09 | -19.84 | CSNK2A1 (casein kinase 2 alpha 1) | protein interactions | 1457 | 934 | 343 | 19454 | 5460 |
CDK12,KPNA1,RPS2,SNRNP70,E4F1,CSNK2A1,COPS5,RBM17,PLEKHO1,DNAJB2,CDC5L,SURF6,DKC1,TMPO,MIF,BRMS1L,NKAP,RPS16,CD274,HCLS1,EEF1B2,AIP,RAD1,PHC1,NUPR1,RBM34,RP9,H2AX,TP53,RPSA,KIF1C,MEPCE,L1CAM,ABCE1,UBE2H,CALU,ALKBH5,PDCD4,EIF3G,ZSCAN25,PRKACB,MTPN,SUB1,AKT1,PPP1R1B,SRC,INTS12,CSNK2B,EIF2S2,GCFC2,RPS3,CREB1,ACACA,HEXIM1,EIF2B3,RPA2,CD2AP,IGFBP3,PPP1R8,SPTBN1,HSPA5,WDR55,ZC3H15,OGDHL,HDAC3,KDM1A,RNF113A,PGK1,PSEN2,PML,BAP1,RPL27,HSPB1,AQP4,YWHAB,MGMT,FKBP4,CTNNB1,BTF3L4,XPO1,RPL6,WWP2,ZCCHC10,IFI16,HSP90AB1,HMG20A,OSBP,PGR,EIF2S1,HNRNPL,RPS10,MEAF6,WDR82,ZHX1,PRCC,GYS1,SIN3A,HGS,ZRANB2,MTA2,EEF2,ISG15,DHX38,SUPT5H,PPIL3,MAX,HNRNPDL,PAX6,RPS4X,RUVBL1,PTPN4,PDIA6,SREK1IP1,RUVBL2,MYO1B,LSM14A,CCT8,PABPC1,RPL31,MAF1,ICAM1,ELAVL4,FTSJ3,CCT2,CIRBP,BRMS1,SFN,PSMA4,STAC3,HNRNPC,COPS7A,MYC,CREBBP,RPL10,ESR2,APEX1,FBXO22,GTF2F1,NFKBIA,NFKBIB,IRF2,CAV2,PIH1D1,EIF4B,CTBP1,ZNF428,PAFAH1B1,RPL27A,UBE2D3,FXR2,SRSF2,PCGF2,YAF2,EP300,DDIT3,HSPA8,SF3B1,HDAC5,FOS,RPS28,XRCC5,OSBPL8,BRD3,MPHOSPH10,ECD,SPP1,SPATS2L,CAV1,MDM2,AKAP17A,CDK9,PRNP,EIF2B5,TOP1,KLF1,RB1,PTPN1,DTD1,DMAP1,THAP1,AURKAIP1,CD2BP2,TAF1D,JPH4,CCT5,MDC1,MSH6,EIF3E,EGR1,THRAP3,ZSCAN5A,RING1,NKRF,TCOF1,FAF1,TFPT,NSDHL,ZNF177,NRP1,HOXC4,STK11,PIP4K2C,TXNIP,HMOX2,GMNN,AR,ATP5F1A,ZNF687,RPL22,DEK,RPL13A,F11R,TMOD3,PTEN,RPS20,RPS12,GANAB,HEXIM2,GTF2A1,CTNNA1,OPTN,STUB1,IFRD1,RPLP0,SNAI2,HSP90B1,METTL14,ZCCHC17,LMNA,CDK1,EIF3J,SF3A1,RPS14,ATG16L1,SAP30BP,PIAS1,MBD3,HMGB1,RPL4,NUCKS1,PPP1R2,EIF5B,CCDC106,MTDH,SQSTM1,SIRT7,MME,RPA3,DVL2,RPL23,PDAP1,STX1A,WDR12,EIF3D,HSPB8,FGF1,DPY30,HMGA1,PRPF19,PIK3R1,TAF7,WDR44,DHX15,SLMAP,SRSF10,EGLN3,RPL7,NOP58,RPLP1,BRD9,HP1BP3,COPS2,RPL8,OTULIN,SART3,RPS11,SAP30,MAK16,JUN,E2F4,RAF1,VDR,NAA15,SSRP1,COPS4,EIF2D,IMMP2L,ANP32B,PCGF6,UBE2A,GTF3C3,GNL1,CBX7,ZNF592,DHX16,PCGF3,RBBP7,RPS24,HNRNPA2B1,PPAN,MEF2C,HSPD1,MORC2,HSP90AA1,SP1,RPS5,BRCA1,MCM3,ATF1,RIOK2,IRF1,CUL3,NFYA,USP13,ERH,RBBP4,RPL7L1,LGALS3,SEC61B,POLR2F,RPS9,POLR3B,EIF3K,VPS72,RSRC1,HEXB,MFAP1,ARMCX3,RNF7,ADNP,CDKN1A,SUPT4H1,SKP1,RNF11,RGS19,NOP53,CFDP1,PSMA3,CRY1,SAT1,SNRK,UPF3B,NKAPD1 |
| 2.461e-09 | -19.82 | IKZF1 (IKAROS family zinc finger 1) | protein interactions | 10320 | 281 | 125 | 19454 | 5460 |
RPL12,GTF2B,SYNCRIP,TOP1,SPPL3,GAPDH,FOXP1,TAF9,RPS2,MPPED2,RPL24,CRBN,DHX9,POC1B,RPL23A,TCEA2,RIGI,KPNA2,FGF12,HNRNPK,NOC4L,CDK2AP2,LSM4,IKZF5,EEF1A1,ZNF581,MTA3,ILF2,CBX3,ALB,UBE2I,ENO1,STUB1,LDHA,MAGOHB,BUB3,NONO,RUNX1,MORF4L1,CTSD,ZMYND19,YPEL5,ATOSB,GID4,HSPA5,NHP2,MBD3,HMGB1,HDAC3,KDM1A,CCND1,FAM161A,ATG16L1,RPS14,WTAP,DYRK2,SDCBP,RPLP2,CEP57L1,SIN3A,CBFB,PPIA,PRPF18,SNRPA1,HNRNPL,HNRNPA1,PRDX1,HMGA1,PRPF19,RPL23,ARMC8,GALC,RPS24,RUVBL2,MKLN1,TRIM21,HNRNPA2B1,MAEA,HSPD1,SLC25A5,AP1M1,RPL28,RUVBL1,RBBP7,PSMA1,RPS7,H1-3,CKS1B,SNRPE,MTA2,RPS11,HDAC11,TUBB4B,ZMAT2,SNRPD2,AP2M1,CDC7,SCNM1,CPSF1,MAD2L2,RBBP4,SNRPB,SMARCE1,IKZF2,CUL2,PSMA4,LMO2,ARMC7,HSP90AA1,RBBP8,DDX5,APPBP2,HSPA8,HDAC5,FAM50B,SAP18,RANBP10,EEF1G,LMO4,LMO3,ISCU,H1-5,ACTL6A,ALKBH3,CTBP1 |
| 2.544e-09 | -19.79 | regulation of smooth muscle cell proliferation | biological process | GO:0048660 | 173 | 88 | 18204 | 5365 |
MIR20A,MIR17,MIR214,GJA1,MIR222,GNAI2,OGN,MIR130A,AIF1,MIR221,TRIB1,XRCC5,JAK2,PTEN,NPPC,CDKN1A,MIR339,STAT1,TERT,MIR301A,NPY5R,MIR448,MIR424,MIR182,TGFB3,AKT1,CDH13,ITGA2,PDE1A,ADIPOQ,TNF,IGF1,IL10,MIR1298,CX3CL1,MIR145,DBH,CTNNB1,TNFAIP3,PHB1,ADAMTS1,CDKN1B,PIK3R1,MIR208A,IRAK4,TACR1,MYD88,PPARG,IGFBP3,MIR503,MIR146A,MIR21,CTNNBIP1,MIR96,HBEGF,MIR137,MIR638,MNAT1,BMPR1A,BMPR2,MEF2C,JUN,IL18,APLN,SRC,IL12A,KLF4,TLR4,MIR140,PIK3CA,CCL5,MDM2,MIR223,FOXP1,IL12B,IFNG,MIR185,IL6,MIR1-1,IGF1R,PDCD4,MIR143,IL13,MIR15A,SOD2,MIR135B,MMP9,MIR34A |
| 2.601e-09 | -19.77 | SEM1 (SEM1 26S proteasome subunit) | protein interactions | 7979 | 162 | 81 | 19454 | 5460 |
KRAS,PSMA5,HUWE1,PSMA2,NEDD8,RPS27A,PSMD12,RIGI,FKBP8,PSME1,UBE3A,BAG2,DDX42,POLR2D,POLR2C,PSMC3,RAD23B,RNF126,RNF181,TAF2,FEN1,UBL4A,SUPT5H,TXNRD1,MAP1LC3B,EEF1A1,JUN,UBR7,EEF2,TOP1,SUMO2,PSME2,SIN3A,PSMB4,UBE2G2,PSMB1,PSMG2,PSMD7,PSMD10,UBFD1,USP15,PSMD3,ENY2,ZFAND2B,NSFL1C,EEF1G,PIAS1,PSMC1,DDX39B,HSPA8,TXNL1,HECTD1,PSMC4,UBLCP1,SUPT4H1,PAAF1,PSMD4,PSMD6,ADRM1,POLR2B,USP38,PRRC2A,STUB1,PSMA6,PSMC5,INTS10,UBE2I,INTS12,POMP,PSMD14,BRCA1,PSMG3,RPF2,PSMA4,CUL2,PSMD1,FBXO7,RBM15B,UFD1,BAG3,USP14 |
| 2.652e-09 | -19.75 | tRNA Charging: Arginine | SMPDB pathways | SMP0111853 | 79 | 56 | 1369 | 531 |
RPL17,RPS20,RPL18,RPLP0,RPL9,RPL23A,RPS12,RPL7A,RPL31,RPL4,RPL29,RPS26,RPLP2,FAU,RPL10,RPS14,RPS24,RPS11,RPS28,RPLP1,RPL26,RPL7,RPL32,RPS16,RPL35,RPL27A,RPL19,RPS2,RPL13A,RPS13,RPL37A,RPL22,RPL35A,RPS10,RPL24,RPL15,RPL23,RPL28,RPS3,RPL27,RPS5,RPS17,RPL10A,RPL39,RPS29,RPL8,RPS7,RPS4X,RPS23,RPS15,RPL3,RPS9,RPSA,UBA52,RPL12,RPL6 |
| 2.652e-09 | -19.75 | tRNA Charging: Cysteine | SMPDB pathways | SMP0111860 | 79 | 56 | 1369 | 531 |
RPL10,RPS11,RPS24,RPS14,RPS26,FAU,RPLP2,RPL35,RPS16,RPS2,RPL19,RPL27A,RPLP1,RPS28,RPL32,RPL7,RPL26,RPL18,RPL9,RPLP0,RPL17,RPS20,RPL31,RPL29,RPL4,RPS12,RPL23A,RPL7A,RPSA,RPS9,RPS15,RPL3,RPS4X,RPS23,RPL6,RPL12,UBA52,RPL24,RPS10,RPL15,RPL35A,RPL22,RPL37A,RPL13A,RPS13,RPS7,RPL27,RPS3,RPL28,RPL23,RPL8,RPS29,RPL39,RPL10A,RPS17,RPS5 |
| 2.652e-09 | -19.75 | tRNA Charging: Serine | SMPDB pathways | SMP0119294 | 79 | 56 | 1369 | 531 |
RPLP1,RPS28,RPL32,RPL7,RPL26,RPL35,RPS16,RPS2,RPL19,RPL27A,RPS26,FAU,RPLP2,RPL10,RPS11,RPS24,RPS14,RPS12,RPL23A,RPL7A,RPL31,RPL29,RPL4,RPL17,RPS20,RPL18,RPL9,RPLP0,RPL12,UBA52,RPL6,RPL3,RPS15,RPS23,RPS4X,RPSA,RPS9,RPL27,RPS3,RPL28,RPL23,RPL8,RPS29,RPS5,RPL39,RPL10A,RPS17,RPS7,RPL35A,RPL22,RPL37A,RPL13A,RPS13,RPL24,RPS10,RPL15 |
| 2.652e-09 | -19.75 | tRNA Charging: Glycine | SMPDB pathways | SMP0111870 | 79 | 56 | 1369 | 531 |
RPL23A,RPS12,RPL7A,RPL31,RPL4,RPL29,RPL17,RPS20,RPL18,RPLP0,RPL9,RPS28,RPLP1,RPL26,RPL7,RPL32,RPS16,RPL35,RPL27A,RPL19,RPS2,RPS26,RPLP2,FAU,RPL10,RPS14,RPS24,RPS11,RPL28,RPL23,RPS3,RPL27,RPL39,RPS5,RPL10A,RPS17,RPS29,RPL8,RPS7,RPL13A,RPS13,RPL37A,RPL35A,RPL22,RPS10,RPL24,RPL15,UBA52,RPL12,RPL6,RPS23,RPS4X,RPL3,RPS15,RPS9,RPSA |
| 2.652e-09 | -19.75 | tRNA Charging: Leucine | SMPDB pathways | SMP0111873 | 79 | 56 | 1369 | 531 |
RPL17,RPS20,RPL18,RPLP0,RPL9,RPS12,RPL23A,RPL7A,RPL31,RPL29,RPL4,RPS26,FAU,RPLP2,RPL10,RPS24,RPS11,RPS14,RPLP1,RPS28,RPL7,RPL32,RPL26,RPS16,RPL35,RPL19,RPS2,RPL27A,RPL22,RPL35A,RPL13A,RPS13,RPL37A,RPL24,RPS10,RPL15,RPS3,RPL27,RPL28,RPL23,RPS29,RPL8,RPL10A,RPS17,RPL39,RPS5,RPS7,RPL3,RPS15,RPS4X,RPS23,RPS9,RPSA,UBA52,RPL12,RPL6 |
| 2.652e-09 | -19.75 | tRNA Charging: Histidine | SMPDB pathways | SMP0111871 | 79 | 56 | 1369 | 531 |
RPS24,RPS11,RPS14,RPL10,FAU,RPLP2,RPS26,RPL19,RPS2,RPL27A,RPL35,RPS16,RPL7,RPL32,RPL26,RPLP1,RPS28,RPLP0,RPL9,RPL18,RPS20,RPL17,RPL29,RPL4,RPL31,RPL7A,RPS12,RPL23A,RPS9,RPSA,RPS15,RPL3,RPS23,RPS4X,RPL6,UBA52,RPL12,RPL15,RPL24,RPS10,RPL35A,RPL22,RPL13A,RPS13,RPL37A,RPS7,RPS29,RPL8,RPS5,RPL39,RPL10A,RPS17,RPS3,RPL27,RPL23,RPL28 |
| 2.652e-09 | -19.75 | tRNA Charging: Glutamic Acid | SMPDB pathways | SMP0111864 | 79 | 56 | 1369 | 531 |
RPL17,RPS20,RPL18,RPL9,RPLP0,RPS12,RPL23A,RPL7A,RPL31,RPL29,RPL4,RPS26,FAU,RPLP2,RPL10,RPS11,RPS24,RPS14,RPLP1,RPS28,RPL32,RPL7,RPL26,RPS16,RPL35,RPL19,RPS2,RPL27A,RPL22,RPL35A,RPL37A,RPL13A,RPS13,RPL24,RPS10,RPL15,RPL27,RPS3,RPL28,RPL23,RPL8,RPS29,RPS17,RPS5,RPL10A,RPL39,RPS7,RPS15,RPL3,RPS4X,RPS23,RPSA,RPS9,RPL12,UBA52,RPL6 |
| 2.652e-09 | -19.75 | tRNA Charging: Aspartic Acid | SMPDB pathways | SMP0111858 | 79 | 56 | 1369 | 531 |
RPL12,UBA52,RPL6,RPL3,RPS15,RPS4X,RPS23,RPSA,RPS9,RPL27,RPS3,RPL23,RPL28,RPL8,RPS29,RPS5,RPL39,RPL10A,RPS17,RPS7,RPL35A,RPL22,RPL37A,RPS13,RPL13A,RPL24,RPS10,RPL15,RPLP1,RPS28,RPL32,RPL7,RPL26,RPL35,RPS16,RPS2,RPL19,RPL27A,RPS26,FAU,RPLP2,RPL10,RPS11,RPS24,RPS14,RPS12,RPL23A,RPL7A,RPL31,RPL29,RPL4,RPL17,RPS20,RPL18,RPL9,RPLP0 |
| 2.652e-09 | -19.75 | tRNA Charging: Valine | SMPDB pathways | SMP0119305 | 79 | 56 | 1369 | 531 |
RPL3,RPS15,RPS4X,RPS23,RPSA,RPS9,RPL12,UBA52,RPL6,RPL22,RPL35A,RPL37A,RPL13A,RPS13,RPL15,RPL24,RPS10,RPL8,RPS29,RPS5,RPL10A,RPL39,RPS17,RPL27,RPS3,RPL28,RPL23,RPS7,FAU,RPLP2,RPS26,RPS11,RPS24,RPS14,RPL10,RPL32,RPL7,RPL26,RPLP1,RPS28,RPS2,RPL19,RPL27A,RPS16,RPL35,RPS20,RPL17,RPL9,RPLP0,RPL18,RPL7A,RPS12,RPL23A,RPL29,RPL4,RPL31 |
| 2.652e-09 | -19.75 | tRNA Charging: Threonine | SMPDB pathways | SMP0119302 | 79 | 56 | 1369 | 531 |
RPL18,RPL9,RPLP0,RPL17,RPS20,RPL31,RPL4,RPL29,RPL23A,RPS12,RPL7A,RPL10,RPS14,RPS11,RPS24,RPS26,RPLP2,FAU,RPL35,RPS16,RPL27A,RPS2,RPL19,RPS28,RPLP1,RPL26,RPL32,RPL7,RPS10,RPL24,RPL15,RPL37A,RPS13,RPL13A,RPL22,RPL35A,RPS7,RPL23,RPL28,RPL27,RPS3,RPL39,RPS17,RPS5,RPL10A,RPL8,RPS29,RPSA,RPS9,RPS23,RPS4X,RPL3,RPS15,RPL6,RPL12,UBA52 |
| 2.652e-09 | -19.75 | tRNA Charging: Asparagine | SMPDB pathways | SMP0111854 | 79 | 56 | 1369 | 531 |
RPL23,RPL28,RPL27,RPS3,RPS5,RPL10A,RPL39,RPS17,RPL8,RPS29,RPS7,RPL37A,RPS13,RPL13A,RPL22,RPL35A,RPS10,RPL24,RPL15,RPL12,UBA52,RPL6,RPS4X,RPS23,RPS15,RPL3,RPSA,RPS9,RPL23A,RPS12,RPL7A,RPL31,RPL4,RPL29,RPL17,RPS20,RPL18,RPL9,RPLP0,RPS28,RPLP1,RPL26,RPL32,RPL7,RPL35,RPS16,RPL27A,RPL19,RPS2,RPS26,RPLP2,FAU,RPL10,RPS14,RPS11,RPS24 |
| 2.652e-09 | -19.75 | tRNA Charging: Lysine | SMPDB pathways | SMP0111874 | 79 | 56 | 1369 | 531 |
RPL9,RPLP0,RPL18,RPS20,RPL17,RPL29,RPL4,RPL31,RPL7A,RPS12,RPL23A,RPS11,RPS24,RPS14,RPL10,FAU,RPLP2,RPS26,RPL19,RPS2,RPL27A,RPS16,RPL35,RPL32,RPL7,RPL26,RPLP1,RPS28,RPL15,RPL24,RPS10,RPL35A,RPL22,RPL37A,RPL13A,RPS13,RPS7,RPL8,RPS29,RPL10A,RPS17,RPS5,RPL39,RPL27,RPS3,RPL28,RPL23,RPSA,RPS9,RPL3,RPS15,RPS4X,RPS23,RPL6,RPL12,UBA52 |
| 2.652e-09 | -19.75 | tRNA Charging: Proline | SMPDB pathways | SMP0112609 | 79 | 56 | 1369 | 531 |
RPS20,RPL17,RPL9,RPLP0,RPL18,RPL7A,RPL23A,RPS12,RPL4,RPL29,RPL31,RPLP2,FAU,RPS26,RPS14,RPS11,RPS24,RPL10,RPL26,RPL32,RPL7,RPS28,RPLP1,RPL27A,RPL19,RPS2,RPS16,RPL35,RPL37A,RPS13,RPL13A,RPL35A,RPL22,RPL15,RPS10,RPL24,RPL39,RPS5,RPL10A,RPS17,RPL8,RPS29,RPL28,RPL23,RPL27,RPS3,RPS7,RPS4X,RPS23,RPL3,RPS15,RPSA,RPS9,RPL12,UBA52,RPL6 |
| 2.652e-09 | -19.75 | tRNA Charging: Alanine | SMPDB pathways | SMP0100356 | 79 | 56 | 1369 | 531 |
RPSA,RPS9,RPS23,RPS4X,RPL3,RPS15,RPL6,RPL12,UBA52,RPS10,RPL24,RPL15,RPL37A,RPL13A,RPS13,RPL35A,RPL22,RPS7,RPL23,RPL28,RPL27,RPS3,RPS5,RPL39,RPL10A,RPS17,RPL8,RPS29,RPL10,RPS14,RPS11,RPS24,RPS26,RPLP2,FAU,RPL35,RPS16,RPL27A,RPL19,RPS2,RPS28,RPLP1,RPL26,RPL32,RPL7,RPL18,RPL9,RPLP0,RPL17,RPS20,RPL31,RPL4,RPL29,RPL23A,RPS12,RPL7A |
| 2.652e-09 | -19.75 | tRNA Charging: Tryptophan | SMPDB pathways | SMP0119303 | 79 | 56 | 1369 | 531 |
RPL26,RPL32,RPL7,RPS28,RPLP1,RPL27A,RPS2,RPL19,RPS16,RPL35,RPLP2,FAU,RPS26,RPS14,RPS11,RPS24,RPL10,RPL7A,RPL23A,RPS12,RPL4,RPL29,RPL31,RPS20,RPL17,RPL9,RPLP0,RPL18,RPL12,UBA52,RPL6,RPS23,RPS4X,RPS15,RPL3,RPSA,RPS9,RPS17,RPS5,RPL39,RPL10A,RPL8,RPS29,RPL23,RPL28,RPL27,RPS3,RPS7,RPL37A,RPL13A,RPS13,RPL35A,RPL22,RPL15,RPS10,RPL24 |
| 2.652e-09 | -19.75 | tRNA Charging: Methionine | SMPDB pathways | SMP0111875 | 79 | 56 | 1369 | 531 |
UBA52,RPL12,RPL6,RPS15,RPL3,RPS4X,RPS23,RPS9,RPSA,RPS29,RPL8,RPS17,RPL10A,RPS5,RPL39,RPS3,RPL27,RPL23,RPL28,RPS7,RPL22,RPL35A,RPL13A,RPS13,RPL37A,RPL15,RPL24,RPS10,RPL7,RPL32,RPL26,RPLP1,RPS28,RPS2,RPL19,RPL27A,RPL35,RPS16,FAU,RPLP2,RPS26,RPS24,RPS11,RPS14,RPL10,RPL7A,RPS12,RPL23A,RPL29,RPL4,RPL31,RPS20,RPL17,RPLP0,RPL9,RPL18 |
| 2.652e-09 | -19.75 | tRNA Charging: Isoleucine | SMPDB pathways | SMP0111872 | 79 | 56 | 1369 | 531 |
RPSA,RPS9,RPS15,RPL3,RPS4X,RPS23,RPL6,RPL12,UBA52,RPL24,RPS10,RPL15,RPL35A,RPL22,RPL37A,RPL13A,RPS13,RPS7,RPL27,RPS3,RPL23,RPL28,RPL8,RPS29,RPL10A,RPS5,RPL39,RPS17,RPL10,RPS11,RPS24,RPS14,RPS26,FAU,RPLP2,RPL35,RPS16,RPL19,RPS2,RPL27A,RPLP1,RPS28,RPL32,RPL7,RPL26,RPL18,RPL9,RPLP0,RPL17,RPS20,RPL31,RPL29,RPL4,RPS12,RPL23A,RPL7A |
| 2.652e-09 | -19.75 | tRNA Charging: Tyrosine | SMPDB pathways | SMP0119304 | 79 | 56 | 1369 | 531 |
RPS7,RPL27,RPS3,RPL23,RPL28,RPL8,RPS29,RPS5,RPL10A,RPS17,RPL39,RPL24,RPS10,RPL15,RPL22,RPL35A,RPL37A,RPL13A,RPS13,RPL6,RPL12,UBA52,RPSA,RPS9,RPS15,RPL3,RPS4X,RPS23,RPL31,RPL29,RPL4,RPS12,RPL23A,RPL7A,RPL18,RPL9,RPLP0,RPL17,RPS20,RPS16,RPL35,RPL19,RPS2,RPL27A,RPLP1,RPS28,RPL32,RPL7,RPL26,RPL10,RPS11,RPS24,RPS14,RPS26,FAU,RPLP2 |
| 2.652e-09 | -19.75 | tRNA Charging: Glutamine | SMPDB pathways | SMP0111862 | 79 | 56 | 1369 | 531 |
RPL27A,RPS2,RPL19,RPS16,RPL35,RPL26,RPL32,RPL7,RPS28,RPLP1,RPS14,RPS11,RPS24,RPL10,RPLP2,FAU,RPS26,RPL4,RPL29,RPL31,RPL7A,RPL23A,RPS12,RPL9,RPLP0,RPL18,RPS20,RPL17,RPL6,RPL12,UBA52,RPSA,RPS9,RPS23,RPS4X,RPL3,RPS15,RPS7,RPL10A,RPS17,RPS5,RPL39,RPL8,RPS29,RPL23,RPL28,RPL27,RPS3,RPL15,RPS10,RPL24,RPL37A,RPS13,RPL13A,RPL22,RPL35A |
| 2.659e-09 | -19.75 | RPL29 (ribosomal protein L29) | protein interactions | 6159 | 237 | 109 | 19454 | 5460 |
BRCA1,RHOB,RPS26,HSP90AA1,SETD7,MYC,BTF3,RPL7L1,DES,RPL10,LMBR1L,RPL37A,SYBU,SEC61B,EMC9,MAP2K1,EIF4B,UFL1,STAU1,G3BP2,ARL6,HSPA8,JADE1,RHOG,AGR2,POU5F1,RPL23,WWP2,RPL6,DDRGK1,RPL7,RPL8,RPL9,PHB1,FBXO32,EED,RPLP1,RPLP2,EZH2,CHMP4C,PPID,RPS23,RHOBTB1,B3GNT2,E2F4,OTUD6B,G3BP1,TRIM37,RPS4X,RPL31,EWSR1,RPS24,MECP2,SPOP,RC3H2,TRIM23,ZBTB38,UBE2H,RPL7A,PPP1CC,RPL22,CCNF,RPS3,METAP2,GSK3A,PSMC5,RPS20,SGTA,RPS12,RPA2,RPLP0,ATG16L1,CDC42,CFTR,CDK7,RPL4,HMGB1,FBXW7,PIAS1,HSPA5,RPA3,BAP1,RPL27,RNF113A,SNRNP70,RPL24,RPS2,RPL10A,ENY2,HDAC6,ZMYND11,RPS16,RPL12,RPL32,RNF8,SRP72,UBL4A,FBP1,TP53,RPSA,MAP2K3,H3C1,VRK1,NOC4L,MEPCE,MDC1,RPL17,SNIP1,RPL23A |
| 2.718e-09 | -19.72 | ASXL2 (ASXL transcriptional regulator 2) | protein interactions | 55252 | 273 | 122 | 19454 | 5460 |
CNP,EEF1E1,UBA52,SF3A1,CDK1,RPA2,PRDX6,ARPC2,H2BC12,BAP1,HSPA5,EIF4E,PPP1CC,TUFM,ATP5F1A,DHPS,HSPA14,MAT2A,UBE2E3,ALB,RTRAF,TUBA1B,ENO1,UQCRC2,RPS3,VIRMA,EEF1A1,CCT5,MTCH2,ILF2,CAPZA2,ARPC3,ACTR2,NDUFS3,CBX3,HSD17B10,SEPTIN7,GLUL,CAPZA1,HNRNPK,FARSA,KPNA2,HUWE1,GAPDH,CSNK2A1,NME2,SEC23A,MTAP,EIF4E2,EEF1B2,RPL12,MBD5,TMPO,PRNP,CAND1,RPS16,PRDX3,MTX2,TRMT112,NDUFA5,ISOC1,GSTM2,HADHA,PHB2,EEF1G,MYC,HNF1B,PRSS1,PFDN2,HSP90AA1,YWHAZ,CCT2,ATP1A3,SNRPD1,PRMT5,SNRPD2,RAN,VDAC2,TUBB,RBBP4,ATP5F1B,PRDX2,RPS7,EEF2,ELF1,PPP2R1A,H1-3,GDI2,NME1,TUBB4B,RTCB,PCNA,RUVBL2,CCT8,SLC25A5,HSPD1,PAX6,PRPS1,VDAC1,RUVBL1,HNRNPF,CTNNB1,HNRNPA1,KRBOX4,STOML2,RIOX2,ISX,UBE2E2,PRDX1,DRG1,DDX1,TRAF6,SKIC8,CCT7,HSP90AB1,CACYBP,PPIA,SNRPA1,SNRPD3,DYNC1I2,TCP1,RPS10 |
| 2.734e-09 | -19.72 | EIF4A1 (eukaryotic translation initiation factor 4A1) | protein interactions | 1973 | 318 | 138 | 19454 | 5460 |
ENY2,HDAC6,COPS5,CD81,USP15,TNKS,CAND1,RPS16,FZR1,RBM42,TMPO,CDC5L,RPSA,KIF1C,CCT5,EEF1A1,H2AX,TFCP2,TNFAIP8L1,PPME1,ILF2,NUPR1,TAF2,SRP72,FAF1,MAP1B,ERO1A,HAPSTR1,ABCE1,HUWE1,MEPCE,EIF3E,CAP2,MAT2A,AKT1,ATP5F1A,AR,ASCC1,EIF3G,RC3H2,PDCD4,UBE2H,CCNF,PSPC1,CTNNA1,METAP2,EIF4A3,NDN,EIF4H,RPP25L,UBA3,VIRMA,NFYB,NEK2,MAEL,CFTR,RPA2,GRM2,METTL14,HEXIM1,UBE2M,RPA3,SNAPC1,HELLS,BAP1,SIRT7,LSM12,SQSTM1,GTF2I,FBXW7,EIF4E,ABCC2,HSPA5,WWP2,EIF3D,AGR2,DRG1,RPL8,FOLR1,PHB1,ATP6V1A,PAIP1,EIF2S1,SUMO2,PPIA,SRSF10,EGLN3,HSP90AB1,TOP3B,RAF1,B3GNT2,OTUD6B,SOX2,PPP2R1A,EEF2,EZH2,CHMP4C,NGB,TRIP4,PABPC1,RPAP3,ZC3H7A,UBE3A,KRAS,G3BP1,RPS4X,CBLL1,RAD21,MYC,PYCR1,CUL3,BTF3,FAS,RPS26,FAM107A,RIT1,LMBR1L,PRMT5,EIF4A2,EIF4E3,MAD2L2,PRRC2A,RPL19,ESR2,WDR77,EIF4B,PIH1D1,PDSS2,BIRC2,HSPA8,CRY1,HDAC5,DDX5,UFL1,UCHL3,STAU1,ADRB2,G3BP2 |
| 2.739e-09 | -19.72 | ZFR (zinc finger RNA binding protein) | protein interactions | 51663 | 287 | 127 | 19454 | 5460 |
IGF2BP1,ELAVL2,UBE2H,MIR145,RC3H2,DEPDC1B,AR,VIRMA,FGFBP1,CCNF,MIR16-1,RPS3,PSPC1,EIF2AK2,HEXIM1,MIR21,KLF4,RPA2,FGF13,RBMS2,MIR34B,UTP23,AATF,FBXW7,MIRLET7I,RNF113A,SQSTM1,RPA3,SIRT7,RPS2,H2AC4,SNRNP70,COPS5,MOV10,RPS16,CAND1,FZR1,TOP1,MIRLET7G,PRR3,ARL4D,COQ8A,MIR106B,ILF2,FURIN,NUPR1,MIR200C,APOBEC3D,PCED1B,TP53,MEPCE,MIRLET7C,MIR16-2,H3C1,TOLLIP,MIR9-3,DHX9,MIR363,SERPINH1,BRCA1,FBXW11,MIR98,SNRPB,MYC,CUL3,HNRNPC,MIRLET7D,MAD2L2,RPL19,MATR3,FBXO22,MIRLET7B,FOXP3,VDAC2,APOBEC3C,FOXS1,ACAA2,LARP4B,SYK,PABPC5,MIR106A,STAU1,HSPA8,EP300,NUP50,DDX5,HADHA,SNRPA,HNRNPD,MIR1-1,MIR31,CPEB1,MIR29C,HNRNPA1,MAP3K14,TRA2A,DDRGK1,PRDX1,NUP35,WIF1,PAIP1,HNRNPL,RPS10,MIR9-1,MIR214,THY1,PHB1,SKA3,HDAC11,SOX2,MIR222,PAIP2B,TOP3B,MRPS17,SSRP1,NUP42,S100A10,MIR155,MIR206,EWSR1,SRSF7,ZYX,NUDT5,RPL31,LSM14A,HNRNPA2B1,MIR9-2 |
| 2.752e-09 | -19.71 | response to external stimulus | biological process | GO:0009605 | 1882 | 666 | 18204 | 5365 |
USP14,NLRP6,H2BC11,TLR7,IRF7,TMEM255A,TRIM29,DHX15,MAP3K14,LTA,FOSL2,CHGA,SHC1,IRF8,CCR1,PPP1CC,HDAC5,MAP2K1,MRC1,FCGR1A,REG1A,OAS1,CCDC92,TRIM22,HNRNPA0,EXOSC4,MIR20A,CCL21,CYBC1,CCR5,FAM3A,BAG3,STAT2,SOX9,CTNNA2,IFI35,BECN1,ATP1B1,LTBR,LITAF,CYP1A1,BANF1,ATP1A2,RAB13,PLSCR3,SRPK2,DPEP1,NOTCH2,SLC6A3,ACTA2,CD209,FCN2,CLPB,IL1A,MAP2K3,TGFB2,DEFB1,GJB2,FGF10,RAB29,DEFB116,TF,LIAS,NCK1,IL18BP,TRIM8,JAGN1,IRF2,GCLC,WASL,CXCR6,NFKBIB,PTPN22,DHX9,VAMP8,FMO1,C1QC,TTC4,UAP1,CCR6,SEMA5A,FOLR2,CCR7,DDIT4,ISG15,BHLHE40,REEP6,CCL20,CXCL1,JCHAIN,WFDC13,CST11,MTDH,ELMO2,HCFC2,CHID1,PPP1CB,NCR3LG1,IFNB1,TRIM11,CAV1,MAVS,CCL27,BLOC1S3,ODC1,PIM2,ZYX,RAB1A,TAX1BP1,MEF2C,MSRB1,POLR3H,CAV3,EFNA5,IFIH1,IRF9,GFI1,SLPI,MYD88,MIR342,MIR421,SNX3,TACR1,ABHD12,CD46,RNASE1,APOBEC3F,CLDN1,CCDC186,TRIM26,PTN,PLPP6,HBEGF,NLRP9,CD4,MIR146A,KCNC1,G3BP1,CNPY3,CCL5,AKAP12,DEFB124,TLR3,TRIM68,GLRA1,PTGER2,CCL17,IGF1R,IER3,IFNAR1,SEMA6C,CDC42,DAPK1,PPIA,MIR142,APOBEC3G,HSPB1,PRDX3,KCNJ2,BPIFB3,CCL3,MIF,APOBEC3D,SCG2,IL12A,REN,BCL10,HTR2A,ELMOD2,SAP30BP,LILRB1,PELI3,MOV10,CSF2,HSP90AA1,STX8,IRF3,AKAP1,TNFSF8,CFL1,CXCL10,VAMP2,TNFRSF14,LSM14A,DRGX,MIR105-1,LRAT,APOBEC3B,PTGER1,CCL18,CASP4,ASIC2,CGAS,NLRP2,TRIM23,CITED1,CXCR3,PPM1D,GJA1,CKLF,MIR17,NLRP3,CCL25,AIPL1,CEBPG,CLDN3,ALDH1A3,TIFA,IRF4,CCR2,F2,AIF1,PDCD1LG2,PLSCR1,FBXO3,MAPKAPK3,DEFB121,CCR3,PLAAT3,ADIPOQ,TNF,RAF1,CX3CL1,RBPJ,PTGFR,IL10,XCL1,NMBR,CX3CR1,TRAF2,VAMP7,PSMA2,PDE12,TRIM6,LY96,PHB1,HMGB1,FGF7,CD1D,MBL2,EPHA2,PLAC8,CXCL12,CXCR1,RNF5,CXCR4,ITGB8,PYCARD,HRAS,IL1RAP,DUSP10,BATF,LGALS3,SRP54,EPO,TPBG,IL34,IKBKB,RBCK1,GPM6A,GAPDH,CYP27B1,SLC17A5,TRIM15,SDHAF4,CNOT7,MKKS,YTHDF2,B2M,ATAT1,RAB32,DROSHA,TSPO,BTG2,GAB1,NQO1,PLGRKT,STRBP,F11R,TRIM52,TNFAIP8L2,PRKCQ,GPNMB,JUP,RHOG,CHMP5,IRAK4,CXCL13,JAML,SLC15A2,PPARG,PTGER4,LYG2,APOBEC3H,RGS1,LYZL4,LPAR1,CXCL8,ARF1,IDO1,SPAG11B,TP53,RCVRN,GNGT2,AZI2,IL21,CLEC7A,SOST,ENDOD1,SOD2,CNP,H2BC12,IL13,P2RY1,ANO3,TMEM33,ITGAV,TMEM87A,MSMP,ACKR3,MIR26B,COMT,UGT1A1,PRDX2,RAC2,ADORA1,LARGE1,BPIFA2,PPIB,TOMM70,CCL11,LXN,CCL8,SEC14L1,NONO,CDK6,TRIM27,SEC11A,TLR4,IFI6,PIP5K1A,BCL2L1,LYZL6,PTEN,JAK2,STXBP1,ACP5,STAT1,USP46,BST2,CCL28,TIRAP,NRP1,MIR187,L1CAM,LACC1,MIR545,CRY1,PRKCE,BAD,KRT8,DEFB114,RAB27A,TUBA1A,DIO2,XBP1,CDC42EP2,CREBZF,RPL13A,TOLLIP,MET,FAS,CD14,EIF2AK2,FLRT3,TUBB4B,KIT,MIRLET7B,PLAA,MIR130A,KLRD1,SLC8A1,UBE2N,CNR1,TMEM229B,CRKL,ROMO1,NFKBIA,AP1M1,PPP1R11,UBE2W,FBXO9,MIR675,CALR,GRPR,SLC1A1,CTNNB1,TNFAIP3,GSTP1,HYAL2,NPR2,MAP1B,MIR95,BAK1,TMEM106A,CCL24,CXCL11,GPX1,RALA,RETN,DEFB129,CEBPE,ZMYND11,AKT1,SERPIND1,IL1B,IFNA13,TLR6,SELENOS,TANK,ISG20,ITGA2,DRD3,SEMA3C,LYAR,IFI27,RIGI,SIN3A,CLEC6A,NMI,TXNIP,PMAIP1,UCN,POLR3F,OPTN,TPT1,CD36,HP,CD80,RBBP9,CDC42EP4,GJA10,LDOC1,TNFRSF1B,IFNK,ATG7,TLR9,PCK2,WFDC5,LECT2,SYNCRIP,EXOC1,LEAP2,MGST2,OCIAD2,SH2D1A,JAK1,LILRA2,DHX16,AQP4,SEMA4C,CDC73,MIR21,IFNA2,EEF1G,DNAJC3,FABP4,CXCL3,FOXP1,CXCL9,G3BP2,MIR223,FGR,POLR3B,RNASEL,RNASE6,DDX1,FCER1G,MX2,IL12B,MMP14,TREML1,PI3,BAX,RTP4,USP2,RSAD2,GTF2F1,IL6,LSM5,GNAQ,IFNA10,CD86,PYDC2,MMP9,BGLAP,VPS26B,TRIM34,CD274,FOXP3,MX1,ENO1,MATR3,TMED1,IFNGR1,ST13,PELI1,DAPK3,SLC1A3,CXCL14,RPL39,VEGFC,TASL,NPSR1,CLCN6,PSPC1,CCL2,CHI3L1,DISC1,SEMG2,FOS,PML,TUBB,PDE2A,ARG2,RNASET2,CRADD,DRD1,KCNJ8,NFKB1,CACNB4,CCL4L1,GNA11,THBD,APOBEC3A,CD2AP,GADD45A,TRAF6,RARRES2,TLR2,GLRB,SLC12A2,TICAM2,TLR10,DPP4,LRTM2,VAMP3,CCL19,TLR5,SFTPD,XRCC5,TBK1,CYRIB,TRIB1,BPGM,ADGRE2,NINJ1,CDK4,LGALS8,NR2F6,IFIT2,PLP2,CD2,ATG16L1,SARM1,SLC2A1,SMAD3,RNASE9,CD63,GPAM,TUSC2,DEFB115,KLRC2,TRIM32,CCN3,PLSCR4,NPC2,TRIM62,LACRT,CMTM7,YES1,CLU,SYK,CH25H,CCR4,NLRP1,WDR83,RAB14,CD40,CCL23,OTULIN,NFKBIL1,S100A8,FCGR2B,APOBEC3C,CREB3,TRIM5,STAP1,TLR1,TICAM1,MTPN,MECP2,ALPL,IVNS1ABP,MIRLET7I,IL23A,VEGFA,SEMA7A,SLC38A2,BNIP3L,LYZ,SAMHD1,TRIM10,IRF1,PQBP1,CCL1,NDUFAF4,TLR8,IFI16,FLRT2,OPRK1,SOX14,ELOVL4,CCT5,CAPN2,BLOC1S5,BPIFB1,ACTR2,TCAP,FBXL3,PIK3CA,CD47,IL17F,SERINC3,FAU,IFNG,TAB2,PDCD4,PRKRA,TMEM45B,CAMP,LGR4,PRDX1,EXT1,IL18,SRC,ADRA1A,NT5C3A,DAG1,ANGPT1,TRIM35,MACO1,ZNF175,COTL1,PHB2,HEXIM1,BACE1,CD58,PIK3CG,REG1B,PDE4B,TFEB,TRIM21,MIR140,FASLG,RNASE4 |
| 2.757e-09 | -19.71 | PFDN1 (prefoldin subunit 1) | protein interactions | 5201 | 170 | 84 | 19454 | 5460 |
TRAF7,ALB,MSN,INPP5K,TUBA1B,SMAP2,LRIF1,GNB1,RPL10,EIF4A2,SNRNP40,ACTB,TSN,PRKACB,PKP4,PFDN4,DTL,PFDN2,PFDN6,RMI1,SNX5,CCT2,DCAF4,RC3H2,TERT,YAF2,NUBP2,JADE1,BAP1,DUSP9,FBXW4,ARHGEF6,RPS28,PRPF4,PDHB,PTN,ARHGEF39,GIT2,MED31,P3H1,SYNDIG1,SAMM50,TYMS,IGBP1,RPLP1,ELSPBP1,EEF1AKMT3,EGLN3,CHGA,CCT7,FZR1,DYNC1I2,SUMO3,CPEB1,PRPF19,FAM20C,PFDN5,NDC80,TUBG1,DCAF5,SKIC8,POC1B,PPP1R12A,CCT8,PSME1,KATNAL1,PDRG1,RIGI,PRPS1,DYNC1I1,KRAS,ROCK2,TUBA1A,KIAA0408,ESS2,FEN1,KBTBD4,YTHDF2,E2F4,MOB3C,NLRP2,TUBB4B,DMAP1,EZH2 |
| 2.795e-09 | -19.70 | NAA15 (N-alpha-acetyltransferase 15, NatA auxiliary subunit) | protein interactions | 80155 | 139 | 72 | 19454 | 5460 |
DRG1,TSNAX,CTNNB1,CSNK2A1,YWHAG,VPS26A,EMC4,CALR,PSMD3,WIF1,MBD5,NAA11,HYPK,RPL35A,SRPRA,SMAD3,RNF126,PSMC3,RBPJ,MTA2,DNAJC2,PDHA1,EZH2,UBR7,GTF2E2,KBTBD4,NAA16,RAD21,CAPZA1,PSMD12,KRAS,TRAFD1,LIPA,MRPS11,DHX9,HAPSTR1,NAE1,DNAJB6,UBE2H,RIT1,SMAD2,CYP1A1,ATG3,BRCA1,BTF3,SUB1,PYCARD,MYC,NAA50,CEP97,UBA3,ROCK1,PSMB6,STAT1,MATR3,RPS20,SYT2,DLST,LMBR1L,CCNF,PSMB7,RPA2,CDC42,SNRNP27,CMAS,EP300,GPHN,HSPA8,XRCC5,SIRT7,BAP1,RPA3 |
| 2.805e-09 | -19.69 | SRSF5 (serine and arginine rich splicing factor 5) | protein interactions | 6430 | 454 | 185 | 19454 | 5460 |
MAP2K1,PIH1D1,TRMT112,ATP6V1C1,TRA2B,HNRNPA0,UFL1,STAU1,SAP18,MRPS7,SPECC1L,SF3B1,EP300,H1-10,FTSJ3,MRPS25,H1-1,NSA2,MYC,HNRNPC,BTF3,APEX1,ESR2,CMTR1,SMU1,MRPL13,GLE1,RPL18,H1-3,HMGN4,RPL31,EWSR1,MAGOH,DDX50,IFI16,RPL6,WWP2,XPO1,MRPL9,DDRGK1,RPS10,LYAR,CLK4,SRSF1,WWP1,ZNF770,RPS15,TMX2,BAP1,NLE1,UBE2H,AKT1,RPF2,RPS17,ZSCAN25,CCR2,SMURF1,DYRK1A,RSL24D1,SRPK2,RPS3,UQCRC2,SF3B6,RBMX2,FGFBP1,SURF4,RBM34,IK,NUPR1,MRPL47,RPSA,IMP4,MEPCE,RPL17,MRPL52,SNIP1,RPL3,MRPS18B,SNRNP70,RPS2,NOL12,CDK12,RPL10A,CMSS1,CENPP,COPS5,FZR1,CAND1,RPS16,DKC1,CDC5L,SURF6,MRPS9,RPL32,USP39,NOP53,NMRAL1,CCDC86,ZCRB1,RPS5,NOP16,CUL3,MRPL16,ZNF668,RPL7L1,RPF1,RPL19,ZNF22,RPL37A,RPS9,EZH2,CHMP4C,MTMR2,TMEM14B,RAF1,MAK16,SRSF4,AKT2,HNRNPA2B1,SRSF8,SRSF7,MRPS11,RPS24,WDR12,RSBN1L,MED4,MRPS26,PRPF19,MRPS35,MARCHF5,TRA2A,EIF3D,MAP3K14,SRSF10,DHX15,RPL8,PHB1,RPLP2,HP1BP3,LMNA,GRM2,ZNF574,RPLP0,RPL26L1,ATG16L1,SF3A1,NPM3,FBXW7,RPL4,HMGB1,NHP2,BRIX1,MRPL20,SIRT7,CLK1,MTDH,SDF2L1,PPIG,RPL26,PPP1CC,RPL13A,CCNF,EIF4A3,PRKRA,LLPH,ILF2,HUWE1,PAK1IP1,RPS13,MRPS18C,RIGI,SMN1,NKRF,RPL23A,SEPTIN7,TIAM1,MOV10,APOBEC3F,MRPL50,AKAP17A,ZBTB2,MRPL24,KRR1,ACTA2,OLFM2 |
| 2.809e-09 | -19.69 | ATP6V1B1 (ATPase H+ transporting V1 subunit B1) | protein interactions | 525 | 109 | 60 | 19454 | 5460 |
CD9,ATP6V1D,STX1A,LAMP2,SUV39H1,RAB22A,MRPL50,SVIP,TCP1,VTI1B,CCT7,VAMP7,CD63,RAB35,ATP6V1A,NHERF1,UBE2B,TFRC,STX12,CCT5,NCSTN,ACTN4,SOX2,SERPINA3,ZBED1,CHMP1B,FLOT1,HNRNPDL,VAMP8,STX8,MYO1B,S100A11,LAMTOR1,CCT2,PKP4,RALB,CTSD,GGH,SLC30A5,DNAJC5,CHMP5,TMOD3,GNB1,CHMP1A,STOM,SLC25A3,TM9SF1,ATP6V1E2,ATP6V1C1,SLC35F6,FTH1,MYH1,ATP6V1G2,KDM1A,ATP6V1G1,ABCC2,CHMP2B,BANF1,SOD1,TBC1D24 |
| 2.809e-09 | -19.69 | RPL10L (ribosomal protein L10 like) | protein interactions | 140801 | 109 | 60 | 19454 | 5460 |
RPS28,RPL27,RPA3,RPL4,FBXW7,RPS15,RPL27A,RPS14,HEXIM1,RPLP0,RPA2,RPS12,RPL37A,RPS3,RPL22,RPL19,RPL10,SLC25A4,RPL35,RPL7A,RPS5,RPS26,CHCHD4,RPS24,RPL23A,RPL3,TRIP4,MAP1B,RPL31,RPL17,RPS27A,RPS13,RPS4X,MEPCE,S100A10,RPS7,EEF2,RPL15,EEF1A1,RPSA,TP53,RPL18,RPS23,RPS11,RPL9,RPL12,RPL8,RPL7,RPS10,RPS16,CAND1,MAP3K14,COPS5,RPL6,MOV10,RPL10A,RPL23,RPS2,RPL24,TUBG1 |
| 2.820e-09 | -19.69 | ZNF326 (zinc finger protein 326) | protein interactions | 284695 | 210 | 99 | 19454 | 5460 |
TRAF6,YWHAH,HNRNPA1,CTNNB1,CNTROB,NUP35,PAIP1,HNRNPL,BUD31,EED,HP1BP3,GYS1,SRSF1,POLR2C,HDAC11,PAIP2B,RAF1,COPS4,SSRP1,EWSR1,RTCB,SRSF7,HNRNPA2B1,THOC6,BRCA1,DCAF4,FBXW11,RNF40,SNRPB,MYC,CUL3,HNRNPC,ESR2,MATR3,SNRNP40,PRMT5,FOXP3,VMAC,NCOA5,EMC9,LARP4B,PPP1CB,WDR77,DUSP14,PABPC5,B9D2,UFL1,SF3B1,DDX5,SNRPA,SNRNP70,MOV10,RBM42,ZBTB2,CAND1,DCUN1D1,TOP1,EIF2B2,PRR3,CD274,RCHY1,ILF2,RNF181,FURIN,NUPR1,IK,APOBEC3D,TP53,HUWE1,SOS2,SEPTIN7,DHX9,DDR1,SLC25A10,IGF2BP1,ELAVL2,UBE2H,NIF3L1,RC3H2,TRIM23,H2BC9,RUNX1,DEPDC1B,PPP1CC,AR,SMURF1,SRPK2,PTEN,SF3B6,UQCRC2,PSPC1,KLF4,AGO1,RBMS2,SF3A1,BRINP1,AATF,RPL4,HMGB1 |
| 2.868e-09 | -19.67 | EBP (EBP cholestenol delta-isomerase) | protein interactions | 10682 | 240 | 110 | 19454 | 5460 |
GJB2,CREB3,HMOX2,ARL6IP6,ENO1,CDIPT,OPTN,VAMP3,SYNGR1,VIRMA,GNAI2,SEC22B,PLP2,SYS1,USE1,STOM,HSP90B1,RPA2,TIMM23,P2RY12,ORMDL1,LRP10,RPA3,TMEM243,TMEM254,VIPR1,TMEM167B,NINJ1,MOV10,TMEM199,TMBIM6,ORMDL3,CD81,TMEM11,TMEM42,BTN2A2,FA2H,HSD17B11,ANKRD46,STX6,FUNDC2,INSIG2,YIPF4,UBIAD1,TMEM31,RUSF1,STX8,YIF1A,ERG28,UNC50,ABCE1,BSCL2,DNAJC30,FKBP8,GPR17,TM4SF20,KDSR,ZDHHC24,FCER1G,CYB561,FAXDC2,TMEM100,FIS1,TMEM229B,EDNRA,THBD,APLNR,GOSR2,VAMP1,OTULINL,CCDC167,MMP14,VAPB,SMCO4,TSPAN15,TMEM106B,CD40,JAGN1,TMEM203,TLCD1,HSCB,STX7,TMEM208,PMP22,SYNJ2BP,EMC6,RNF152,FXYD6,C2CD2L,RB1CC1,STX5,MITF,TLCD4,TMEM97,TSPO2,EGLN3,NEU1,RAF1,MFSD6,SAP30,NCSTN,VAMP2,RPN1,CYB5B,TMEM14B,STX12,TMEM147,TMEM60,PLPP6,SACM1L |
| 2.890e-09 | -19.66 | EBNA-1 (protein-coding) | protein interactions | 3783709 | 202 | 96 | 19454 | 5460 |
TBCE,PSMD1,H1-10,FTSJ3,RPS5,RPS26,CYB5R3,TACO1,VDAC2,PRMT5,ACTB,RPL35,GNB1,SNRPB2,PGRMC1,RPL27A,RRAGA,WDR77,SYK,RAB6A,PRDX3,STK26,HSPA8,SF3B1,HNRNPA0,STOML2,GSTM3,DDX50,PRDX1,YWHAH,PSMD10,PHB1,RAB35,SUMO2,PPIA,NUP37,FAF2,PDHA1,SNRPE,PABPC1,ACTR1B,TRIM21,MYO1B,XPNPEP1,CHCHD2,RPL28,NAA50,SLC25A1,RPS3,STUB1,RPS12,ALB,UBE2I,GANAB,RPL10L,RPL13A,EIF4H,BCCIP,SUMO1,SPR,TIMM23,HNRNPH3,RARS1,PNO1,TXNDC17,PML,RPL27,PRIM2,PRDX6,RAB33B,ARPC2,SMC4,TOMM20,LRRC40,CSNK2A1,HP,SMCHD1,RPL10A,KPNA1,ALYREF,SDHB,SRP14,AIFM1,ADD1,RPL35A,DBT,ATP5PB,CBX3,SRP72,RAB1A,CPNE2,RAB13,NUP107,CTNNBL1,EIF3E,RPL17 |
| 2.947e-09 | -19.64 | tRNA Charging: Phenylalanine | SMPDB pathways | SMP0111876 | 81 | 57 | 1369 | 531 |
RPL15,RPL24,RPS10,RPL35A,RPL22,RPL37A,RPS13,RPL13A,RPS7,RPL8,RPS29,RPS17,RPS5,RPL39,RPL10A,RPL27,RPS3,RPL23,RPL28,RPSA,RPS9,RPS15,RPL3,RPS4X,RPS23,RPL6,RPL12,UBA52,RPL9,RPLP0,RPL18,FARSA,RPS20,RPL17,RPL29,RPL4,RPL31,RPL7A,RPS12,RPL23A,RPS11,RPS24,RPS14,RPL10,FAU,RPLP2,RPS26,RPL19,RPS2,RPL27A,RPL35,RPS16,RPL32,RPL7,RPL26,RPLP1,RPS28 |
| 2.971e-09 | -19.63 | TPM4 (tropomyosin 4) | protein interactions | 7171 | 221 | 103 | 19454 | 5460 |
HNRNPK,DUSP19,DUSP21,KLF10,CAPZA2,DISC1,RNF181,FURIN,ILF2,CAPN2,TP53,ATP5PB,MRPL50,PRNP,CDK9,TMPO,PTP4A3,COX4I1,ADD1,SNRNP70,LANCL2,COX5A,DPP4,TPM3,COPS5,PPM1D,HDAC6,HMGB1,BAP1,RHOU,RAB9A,METTL14,WTAP,TMOD1,ATG16L1,CDK7,KLF12,CFTR,CTSB,DYRK1A,SRC,SMURF1,PSMA6,CCNF,TRIM24,PPM1M,PPTC7,MAPRE1,UBE2H,ATP1A1,NDUFB10,AKT1,AKT3,AR,USP14,PPP1CC,TRIM37,G3BP1,PSMA1,TNF,TRIM26,UBE2A,ATF3,ZYX,PICK1,CHMP4C,IRF8,EZH2,RHOBTB1,RND3,TOP3B,RAF1,SNAPIN,ACTN4,ISG15,RHOH,FHIP1B,FOLR1,CORO1C,SRSF2,FOS,EP300,HACD1,HSPA8,KLF3,PIH1D1,PPP1CB,APEX1,ESR2,PSMB6,PPP1R3C,ELK3,DLST,SRXN1,CKB,VMP1,SERPINH1,SP1,PYCARD,MYC,PSMD1,PDE4B,BTF3 |
| 2.985e-09 | -19.63 | COX6C (cytochrome c oxidase subunit 6C) | protein interactions | 1345 | 124 | 66 | 19454 | 5460 |
COX7A1,PHB1,COX4I1,RCHY1,AIFM1,CYB5A,RMND1,SLC25A12,ATP5PD,COX5A,CALR,TMEM70,SMDT1,SFXN1,NDUFA4,NDUFB5,COX8A,DNAJC30,KRAS,CHCHD2,COX7B,E2F4,MTCH2,APOO,COX4I2,CAPZA2,PDHA1,NDUFS3,SLC25A24,NDUFA12,CCNF,VDAC2,MGST3,RPL10,PARL,COX6B1,AUH,RAB2A,NDUFB10,ATP5F1A,HTRA2,UBE2H,PTTG1,SNAPC1,RPA3,HADHA,SAT1,PRKCB,PGK1,HSPA8,SLC25A51,PDHB,PTN,NDUFS2,METTL14,STOM,HSP90B1,COX7B2,COX6C,MED23,RPA2,VAPB,KLF3,CYC1,NDUFA5,TTI2 |
| 3.019e-09 | -19.62 | TAGLN (transgelin) | protein interactions | 6876 | 69 | 43 | 19454 | 5460 |
RBM27,ADK,NME2,GSTO1,CDKN1B,FKBP1B,SUGP1,RNF14,GORASP2,BAG3,CFL1,PPIB,SNX3,DUSP3,DUSP6,ENO2,ENO1,SMAP2,MRPL53,FABP5,SNX12,ACAA2,PLS3,FKBP1A,B3GNT2,FABP7,TOP3B,MSX2,EEF2,ISG15,CDC42,SRPRB,STAU1,HSPE1,ETFA,UCHL3,YKT6,AIF1L,FKBP2,HSD17B10,HINT1,GPX4,JAK1 |
| 3.041e-09 | -19.61 | DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2) | protein interactions | 1781 | 279 | 124 | 19454 | 5460 |
LUC7L3,HNRNPH3,DCTD,PDCL,HEXIM1,RPA2,DCTN4,CDK7,CFTR,PIP5K1A,RBFOX2,HSPA5,BRIX1,TMEM209,DCTN6,SLC39A9,BAP1,RPA3,MAPRE1,UBE2H,BICD2,EIF3G,DEPDC1B,FAM110B,MLF1,VIRMA,DYNLT3,ADRM1,PSMC5,STUB1,CCNF,CCSER2,MLLT11,AGPAT5,RPL15,MGARP,NECAP2,ACTR1A,CCT5,TP53,RPS13,DYNC1I1,PSMA5,AKAP12,MAP4,TSNAX,ADD1,AIP,ITK,PTPN1,TRMT112,PSMB7,PAFAH1B1,UNC45A,PSMC1,STAU1,HNRNPA0,GOSR1,DCTN3,COMMD2,HSPA8,XRCC5,PFDN6,RIT1,PFDN4,RPS5,PFDN2,RPS26,PSMD14,BRCA1,ELMO2,CCT2,TBC1D1,PSMD1,CUL3,MYC,APEX1,ESR2,PSMB6,PSMD6,DYNLL1,RBBP4,KBTBD2,PSMD4,PHKB,DYNLRB2,SNRPD2,EIF3K,MOB3C,PPID,NDUFS6,TUBB4B,MSX2,NUDCD3,RPL28,CCAR1,PFDN1,RUVBL1,GNL1,KRAS,PSMA2,HNRNPF,RBBP7,ACTR1B,RUVBL2,ABCF1,PABPC1,CCT8,BCKDK,SPHK2,DDX1,PSMD10,FKBP4,BTF3L4,NDC80,PFDN5,PSMD3,CCT7,HSP90AB1,ERLIN1,EGLN3,DYNC1I2,TCP1,NOB1 |
| 3.074e-09 | -19.60 | PSMC3 (proteasome 26S subunit, ATPase 3) | protein interactions | 5702 | 396 | 165 | 19454 | 5460 |
IFI16,PIK3R1,PSMD3,DPY30,YWHAH,CTNNB1,PSMD10,TRAF6,AGR2,UBFD1,RB1CC1,RPL23,PSME2,PSMB4,PPP2CB,PSMB5,COPS2,KRT8,CCAR2,SUMO2,SLMAP,DIRAS3,EGLN3,HSP90AB1,NAA15,SOX2,PPP2R1A,ISG15,EZH2,PLS3,RPN1,MOB3C,CPE,CYP2C9,RNASEH2C,GADD45A,RUVBL2,UBE3A,TRMO,PSMA2,PSMA1,KRAS,RUVBL1,PSMD12,RPS27A,EIF2D,RFC2,ALDH1L1,MYC,CDKN3,TXNRD2,CUL3,PSMA4,PSMD1,RNF40,BAG3,POMP,BRCA1,PSMD14,BAX,S100A6,IRF2,LMBR1L,GTF2F1,ANAPC2,PSMD4,STAT1,PSMD6,TAB1,PSMB6,LRIF1,ESR2,NCKAP1,PSMB3,BORCS6,PSMB7,PAK2,TPD52L1,FLYWCH2,TXNL1,DR1,PSMA3,UFL1,TSR3,EYA3,PHB2,PXMP2,PSMC1,DDI1,MOV10,KXD1,EMC4,ZFAND2B,CCDC92,PSMG2,PSMD7,ECD,PSMB1,ASB11,FZR1,PRNP,MDM2,CDC5L,TP53,INSIG2,PSMB9,TMEM31,NUPR1,RAD23B,ZFAND2A,PSMC3,MAP1B,PSME1,SEM1,HUWE1,PSMA5,SCML1,VTA1,FBXO25,MEPCE,PSEN1,STX11,FKBP8,PSMB2,PTPN11,USP14,AR,TADA3,PDCD4,ATP1A1,NAPA,ZBTB38,UBE2H,PSMG3,CCNF,PSMA6,PSMC5,UBE2I,MSN,ADRM1,SMURF1,VIRMA,ATG16L1,PSMC4,NEK2,NDUFAB1,PAAF1,CFTR,UBLCP1,GRM2,JKAMP,E2F6,HEXIM1,UBE2M,ACACA,BAP1,PML,SIRT7,SQSTM1,MAVS,KDM1A,SMC4,DESI1,EIF4E,CXXC1 |
| 3.074e-09 | -19.60 | EIF4G1 (eukaryotic translation initiation factor 4 gamma 1) | protein interactions | 1981 | 396 | 165 | 19454 | 5460 |
HSPA8,NUP50,STK26,ATPAF2,PSMC1,POLA2,FTL,G3BP2,FXR2,UFL1,STAU1,PPP1CB,MFAP1,EIF4B,PAK2,EMC9,VPS18,RPS9,LMBR1L,CMTR1,EIF3K,DLST,APEX1,NCKAP1,ESR2,EIF4A2,MATR3,PSMD6,RPL35,DYNLL1,PSMD1,BTF3,SAMHD1,MYC,PSMA4,CDKN2D,CUL3,SFN,HSP90AA1,HTRA2,RIT1,PSMD14,BRCA1,ZC3H7A,UBE3A,PABPC1,PSMD12,RAD21,POLDIP3,ENKD1,G3BP1,KRAS,HNRNPF,PPP2R1A,ISG15,TRAF2,OTUD6B,MSX2,LGR4,B3GNT2,TOP3B,RAF1,E2F4,RPS11,IFT22,EIF1AX,PDHA1,RAB31,PPP2CB,PHB1,CNTROB,RPS10,CCAR2,SUMO2,YWHAG,MRPL9,YWHAH,EIF3D,DDX50,PSMD3,CDC26,WWP2,HNRNPD,YWHAB,DRG1,HSPB1,RPL23,AGR2,BAP1,SIRT7,PML,EIF4E,HSPA5,RPS15,FBXW7,EIF3J,GABARAPL2,PSMC4,SF3A1,EEF1E1,UBE2M,HECTD1,ACACA,DCTN4,CDK1,PSMC5,MSN,PSPC1,RPS3,CCNF,PSMA6,METAP2,DYRK1A,SRPK2,VIRMA,NDN,ADRM1,FBXO7,RPS17,ATP5F1A,NTAQ1,ST13,RACGAP1,EMILIN1,RPL7A,PTTG1,PDCD4,MAPRE1,UBE2H,EIF3G,RC3H2,ABCE1,RAB1A,PSME1,PSEN1,MRPL22,RPS13,RIGI,EIF3E,H3C1,EIF4EBP2,NAA35,FBP1,GCHFR,MAMDC2,IPO8,PSMC3,SRP72,TAF2,NUPR1,SRP14,RBM42,CDK9,NCBP2,TMPO,FZR1,SPPL3,RPS16,HDAC6,CALR,EDEM1,USP3,RPS2,PSMD7,SNRNP70 |
| 3.121e-09 | -19.59 | RPL15 (ribosomal protein L15) | protein interactions | 6138 | 487 | 196 | 19454 | 5460 |
MATR3,RPL10,CMTR1,PRMT5,FTSJ3,RPS26,NSA2,DNAJB6,MYC,BTF3,ZNF692,UFL1,STAU1,SPECC1L,RPS28,RAB5A,PIH1D1,RPL27A,MTF1,RPS10,EIF2S1,LYAR,DYNC1I2,RAB35,SRSF1,RBM5,AGR2,SPHK2,MAGOH,DRG1,IFI16,WWP2,RPL6,DDRGK1,KRAS,RPS4X,RPL31,PABPC1,ZRANB2,RPL18,RPS23,TRMT1L,MAGEB10,DNAJC25,SOX2,RPS7,RPL10L,RSL24D1,SRPK2,PSPC1,RPS3,EIF2S2,MACROH2A1,MECP2,RC3H2,ZBTB38,UBE2H,RPF2,RPL7A,RPS15,HSPA5,BAP1,RPL27,PML,NLE1,RNF113A,RPA2,FGF13,CFTR,FZR1,CAND1,DNAJC1,RPS16,RPS27L,DKC1,SURF6,RPL32,SNRNP70,RPL24,RPS2,CDK12,USP15,RPL10A,ENY2,COPS5,API5,NEDD8,MEPCE,RPL17,RPL3,RBM34,DNAJC2,UBL4A,TP53,RPSA,ACTB,RPL35,RPF1,RPL7L1,RPL19,RPL37A,SEC61B,RPS9,BRCA1,RHOB,RPS5,RIT1,CUL2,CUL3,COIL,G3BP2,CCDC86,ARMCX3,EMC9,WDR77,RPL7,RPL9,FOLR1,RPL8,PHB1,RPLP2,RPLP1,RPL23,DICER1,MAP3K14,G3BP1,TNF,GTF3C3,RPS27A,SLC25A5,PPAN,SRSF8,RPS24,EZH2,CHMP4C,NGB,RPS11,POLR2C,B3GNT2,RAF1,SAP30,NDN,RPL13A,RPL22,CCNF,METAP2,EIF4A3,GSK3A,PRKRA,RPS12,RPS20,DNAJC19,ZNF687,RPL26,PPP1CC,TUFM,NPM3,NF2,FBXW7,HMGB1,RPL4,PIAS1,BRIX1,RPA3,SIRT7,PRKCB,MTDH,METTL14,GRM2,RPL26L1,RPLP0,MACROH2A2,RPS14,EEF1E1,CDK7,DCUN1D1,RPL35A,PRNP,CDK9,MDM2,RPL12,KRR1,RCHY1,ARL10,PWP2,SPP1,HDAC6,HUWE1,VRK1,RPS13,RPL23A,LLPH,TOPORS,ILF2,MAP1LC3B,EEF1A1 |
| 3.253e-09 | -19.54 | EXOSC4 (exosome component 4) | protein interactions | 54512 | 197 | 94 | 19454 | 5460 |
UFL1,STAU1,LUM,UPF3B,HSPA8,PSMA3,C1D,EMG1,PALS2,GTF2IRD1,PIH1D1,AKR1A1,UMPS,MED17,ESR2,RPL10,RSRC1,PELO,RPL37A,H1-10,RIT1,PSMA4,BTF3,RPS29,KRAS,PSMA1,ETFA,RPS4X,OSTM1,EZH2,EXOSC3,E2F4,RPS10,EED,FAHD1,ZCCHC9,HNRNPD,MPHOSPH6,DRG1,IFI16,WWP2,HNRNPA1,DIS3L,DDRGK1,WDR3,FBXW7,SNAPC1,LRRC8D,EXOSC4,MTDH,RNF113A,SDCBP,GRM2,WTAP,ATG16L1,PSMC4,GTF2H4,CDK7,SMURF1,NMI,PSPC1,RPS3,CCNF,LIG3,PSMA6,EIF2S2,PTEN,MECP2,IVNS1ABP,RC3H2,EXOSC1,RBM7,UBE2H,DHPS,KPNA6,PSMA5,TOM1,PHF1,MAP1B,ABCE1,CHAMP1,DXO,TP53,PPARA,EEF1A1,EXOSC8,FZR1,RPS16,EIF2B5,CDK9,EIF4E2,PWP2,SNRNP70,GTF2E1 |
| 3.291e-09 | -19.53 | TP53BP1 (tumor protein p53 binding protein 1) | protein interactions | 7158 | 514 | 205 | 19454 | 5460 |
ANXA7,CDKN1A,PSMC1,NUP50,YWHAZ,BRCA1,MED10,SMARCE1,CHP1,MAD2L2,DYNLL1,MED17,PELO,STK16,SKA3,EZH2,E2F4,CSNK1E,RFC2,GTF3C3,MCM6,ATF3,HNRNPA2B1,BCKDK,SLC35D1,RB1CC1,MED4,HNRNPD,KDM2A,ZNF207,BABAM1,DPY30,CACYBP,TYMS,MAP1LC3A,THOC2,WTAP,LMNA,CDK1,MED30,PSMC4,MEF2A,DGCR8,SGF29,FLCN,ANAPC16,SIRT7,PPM1G,RPA3,TADA1,TADA3,NONO,TAF5L,CDC16,DEK,VIRMA,UBE2L3,MGST3,PTEN,UBE2I,ENO1,DHRS7B,NUDT16,ILF2,TOPORS,VAC14,CD2BP2,AURKAIP1,RIGI,MDC1,SMN1,RNF20,EGR1,NSMCE3,LSM4,SFXN1,TOPBP1,DNAJC7,ERCC3,MOV10,NFKB1,ZBTB2,PLGRKT,SHLD1,ETV6,MED31,ACAA2,GTF2IRD1,MRPS7,RAMAC,TRIM22,MED13L,EP300,SF3B1,HSPA8,XRCC5,HIRA,DDX39B,DNAJB6,PSMD14,CIRBP,RMI2,CDKN3,HNRNPAB,MYC,CREBBP,APEX1,ESR2,KBTBD6,PPP5C,PSMD6,FBXO22,PSMD4,MCPH1,ANAPC2,AAMP,HGS,TAF10,SMARCB1,MTA2,MED9,DHX38,TRMT1L,TOP3B,HNRNPDL,RUVBL1,H1-6,ZNF609,PELI1,EWSR1,CDC23,POU5F1,IFI16,SUMO2,DBR1,EED,SRSF1,PRCC,RBM5,SIN3A,HEXIM1,RPA2,CFTR,GTF3C4,PPP1R8,SUMO1,GTF2H4,BCL6,KDM1A,PML,NBN,DDX46,SNAPC1,UBE2H,ANAPC4,ATP1A1,FMO1,STN1,SPOP,MED22,SUB1,MORF4L1,CCNB1,PPP1R10,CSTF3,BUB3,PSMC5,MID1IP1,DCLRE1C,PSPC1,BIRC5,PSMC3,RAD1,RNF8,TP53I3,CBX3,CDK8,DDX42,H2AX,TP53,CAPZA1,MNAT1,TOLLIP,NUP107,H3C1,ZBTB25,BHLHE40,ZNF451,NOSIP,KPNA1,ZDHHC15,LSM3,AKAP8L,H2AC4,MED27,TSEN34,API5,TMA16,COPS5,USP3,MYL12A,TMPO,SPPL3,COX4I1,SDHB |
| 3.380e-09 | -19.51 | RUVBL2 (RuvB like AAA ATPase 2) | protein interactions | 10856 | 580 | 227 | 19454 | 5460 |
TERT,CFDP1,CRY1,SKP1,ACTL6A,USP39,PPARG,SNRPD2,AP2M1,VPS72,ACTB,RBBP4,PRPF31,RFC5,CUL3,HNF1B,ACO2,PFDN6,ILK,RIT1,PFDN2,HSP90AA1,BRCA1,FAS,PCNA,INO80C,TRIP4,RPS27A,GNL1,RBBP7,B3GNT2,RAF1,RPS11,POLR2C,CHMP4C,EZH2,HP1BP3,PHB1,RPL9,DNM2,CACYBP,SNX2,SNX1,CCAR2,NOP58,ACTL6B,ATG7,HNRNPA1,INO80E,PSMD3,TAF7,HMGA1,UBXN6,DCAF11,TERC,PSMD10,PRPF4,NCDN,MME,RPA3,SOD1,SMC4,FBXW7,CDK7,UQCRC1,ARHGAP1,ATG16L1,MACROH2A2,TTI2,STOM,JUP,CFAP298,TUBA1B,SMAP2,PELP1,CCNF,VIRMA,COPE,TMOD3,NDN,AR,PPP1CC,CTNNBIP1,FBXO7,CDC73,TXNIP,HSD17B10,HINT1,TFPT,PTGES3,FBXO25,DNAAF10,HUWE1,TSSC4,MAP2K3,EEF1A1,TBK1,ILF2,DMAP1,EEF1AKMT3,RCHY1,H2AZ1,WDCP,AIFM1,ASNSD1,CDK9,MDM2,KCTD15,ARF6,SUV39H1,HDAC6,NFKB1,BRD3,CRBN,NME2,DR1,EP300,HDAC5,HSPA8,XRCC5,RFC4,BMPR1A,STAU1,UFL1,PIH1D1,FDFT1,CSNK1A1,EIF4B,MCPH1,ZNHIT6,RDM1,POLR2B,PSMB6,PSMD6,TRIM29,MATR3,BAG3,PSMD1,BTF3,SFN,MYC,H2AZ2,RPAP3,DNAJB4,RUVBL2,RPS4X,RUVBL1,PSMA1,KRAS,HNRNPF,KIF2A,ISG15,SOX2,MAX,MOB3C,PDHA1,H2BC1,EED,HSP90AB1,DYNC1I2,MEAF6,PAIP1,CTNNB1,XPO1,YWHAG,WWP2,IFI16,HSPB1,TNFSF13,CBL,AGR2,DERL1,RNF113A,BAP1,HSPA5,KDM1A,NTPCR,CFTR,POLR1D,NEK2,AGO1,LUC7L3,UBE2M,HEXIM1,FGFR1,RPA2,MACROH2A1,PSMC5,PHAX,NOPCHAP1,ADRM1,GORASP2,MORF4L1,SMARCA5,SLC25A1,AKT1,UBE2H,ZBTB38,EIF3G,MAP1B,METTL18,SNIP1,FKBP8,MEPCE,PDRG1,KPNA2,H2AX,RPAP2,MTCH2,ZNHIT1,PSMC3,NUPR1,RNF8,DDX42,CD274,CDC5L,TMPO,DKC1,FZR1,CSNK2A1,MAP4,TMOD2,USP15,RPS2,TAF9,KPNA1,SHC1 |
| 3.381e-09 | -19.51 | YBX2 (Y-box binding protein 2) | protein interactions | 51087 | 285 | 126 | 19454 | 5460 |
CASC3,ELAVL2,ZSCAN25,RPS17,RPS3,MIR16-1,RPS20,PHAX,MIR7-1,MIR21,ZNF574,RPL26L1,HEXIM1,MIR34B,RBMS2,CFTR,MIR1-2,MRPL10,RBM22,MRPL40,FBXW7,MRPL17,RPS15,MRPL20,UTP23,MIR205,MIR10B,MIR34C,RNF113A,MIRLET7I,MPHOSPH10,MIR34A,RPS2,NOL12,CMSS1,MOV10,MRPL50,ABHD8,MIRLET7G,RPS16,MRPL24,MALSU1,MIR429,DKC1,KRR1,SYNCRIP,MRPS9,MIR106B,MIR25,PRR3,LLPH,MIR17,MRPL51,MRPL49,MRPL11,MRPL47,STRBP,MIR200C,H2AX,DDX39A,NOC4L,RPL17,MIR16-2,MRPL22,MIRLET7C,MEPCE,NKRF,MIR200A,MIR9-3,MRPS18B,CD226,ZCRB1,FYTTD1,H1-1,NSA2,MIR363,RPS5,ICAM1,MRPL16,ZNF668,RPF1,MRPL23,RPL19,ESR2,MIRLET7D,ZNF22,RPS9,MRPL13,MIRLET7B,MRPS18A,FGF17,PABPC5,MRPL57,STAU1,MRPS7,NGRN,CCDC86,SF3B1,MIR31,ZCCHC9,MRPL18,MRPS26,RSBN1L,MIR1-1,MIR221,MRPS35,MRPL9,MIR29C,RPS10,SRSF1,MIR7-2,MIR141,MIR214,HP1BP3,HDAC11,GLE1,SUPT5H,DNAJC25,H1-3,MIR222,MIR155,H1-6,SRSF4,PPAN,RPL31,MRPS11 |
| 3.385e-09 | -19.50 | DDX24 (DEAD-box helicase 24) | protein interactions | 57062 | 577 | 226 | 19454 | 5460 |
FGFBP1,CSNK2B,PAFAH1B3,ZNF330,RPS3,BCCIP,SRPK2,CFL1,RPL7A,SLC25A1,RPF2,UBE2H,ZBTB38,RC3H2,MECP2,RNF113A,NLE1,HSPA5,SSR1,RPA2,SYNCRIP,SURF6,KLF9,DKC1,FZR1,CAND1,RPS16,TPM3,GAPDH,TMA16,CSNK2A1,RPL10A,RPS2,NOL12,SNRNP70,H2AC4,RPL3,SNIP1,RPL17,H3C1,TP53,RPSA,DLST,TRIM44,ESR2,RPL10,PSMB6,SNRNP40,FBXO22,THAP7,PSMA4,HNRNPC,SFN,HNRNPAB,MYC,PRSS1,NSA2,H1-1,PSMD14,H1-10,FTSJ3,LAMTOR1,LCN1,RAB5A,EP300,HSPA8,SNRPA,RFC4,PHB2,STAU1,ZNF692,UFL1,GLRA2,FGF17,BET1,RPL27A,SYK,SDC2,S100A8,SRSF1,FABP5,HSP90AB1,SNRPA1,LYAR,RPS10,EIF2S1,DDRGK1,ZCCHC10,RPL6,CNOT2,IFI16,YWHAB,HSPB1,MGMT,POU5F1,MYO1B,RPL31,RPL28,RPS4X,HMGN4,VDAC1,KRAS,RPS7,SOX2,MOB3C,RPL18,PTEN,UBE2I,ALB,PRKRA,ENO1,EIF2AK2,CCNF,RPL22,VIRMA,RPL13A,TXN,PPP1CC,ATP5F1A,ZNF687,CTSD,TCEA1,MTDH,SIRT7,RPA3,BRIX1,FBXW7,RPL4,DGCR8,NPM3,KLF12,CCND1,RPS14,MACROH2A2,KRT7,RPLP0,RPL26L1,GRM2,JUP,LMNA,TSR2,KRR1,SRP14,ZBTB2,CDK9,MDM2,TOP1,ARF6,SLC25A46,MOV10,GRSF1,RPL23A,EIF3E,FASTKD5,BCS1L,GGCT,RPL15,MAP2K3,AURKAIP1,SERPINA1,UBE2B,IFT57,RPS9,RMDN3,RPL37A,KRTAP3-1,FAU,RPL19,RPL35,EIF4A2,MCM3,GGH,ZNF668,GRB10,CUL3,AUH,HSP90AA1,YWHAZ,RHOB,BRCA1,PSKH1,PSMA3,AZGP1,G3BP2,POLA2,COIL,CDSN,HSCB,PPP1CB,H1-5,SLC25A3,USP39,KRT8,RPLP2,PSMB5,FBXO32,PHB1,MRTO4,RPL8,RPL7,SPTAN1,NOP58,IDO1,HNRNPA1,PRDX1,LHX2,RPL23,LYZ,HNRNPD,DDX23,WDR12,CSTA,RPS24,PPAN,HNRNPA2B1,TRIP4,SLC25A5,SRSF4,ACTN4,MAK16,OTUD6B,SART3,RBPJ,RAB6B,EXOSC3,SKA3 |
| 3.425e-09 | -19.49 | AFG3L2 (AFG3 like matrix AAA peptidase subunit 2) | protein interactions | 10939 | 336 | 144 | 19454 | 5460 |
SFXN1,RNF167,CLPB,SLC16A1,DNAJC30,FKBP8,MDC1,FASTKD5,MRPL11,MTCH2,ATP5PB,METTL15,AURKAIP1,APOO,GJA10,GFM2,NDUFB4,COX4I1,AIFM1,SSBP1,RAC2,HSD17B11,ARF6,SLC25A12,LMAN1,SLC25A46,GRSF1,CHCHD1,BECN1,TMEM70,DNAJC7,DNAJC4,MAIP1,RHOU,INPPL1,RPA3,MAVS,GFM1,SLC25A51,FBXW7,NF2,CRYZ,TOMM20,TIMMDC1,ATG16L1,CDC42,SAMM50,RPA2,CYC1,MTRES1,CTNNA1,UQCRC2,CCNF,OPTN,PTPMT1,PTEN,SEC61A1,RHOJ,YES1,MGST3,SRC,VIRMA,UQCRQ,UBB,TUFM,DNAJC5,ATP5F1A,RC3H2,DNAJC19,UBE2H,ATP1A1,NDUFA4,HSPD1,COX8A,HINT2,G3BP1,KRAS,CHCHD2,RAD21,IMMP2L,FLOT1,TUBA1A,PDHA1,RPN1,EZH2,DUSP6,PHB1,GATD3,RHOH,RMND1,COX14,EGLN3,DIRAS3,NDUFS8,MTRF1,DDRGK1,RHOG,AK2,ARMC8,DCAF11,MRPS26,PEX3,HAX1,RNF139,EXD2,DUSP9,NGRN,AKAP1,PHB2,DUSP26,STAU1,HSCB,EMC1,UFL1,G3BP2,PXMP2,TOMM22,TIMM29,RND2,PDP2,CSNK1A1,SLC25A3,MTG1,CCDC90B,TACO1,SEC61B,ANAPC2,FBXO22,MAD2L2,PARL,ESR2,RAB11A,PMPCA,CUL3,MTG2,AUH,MYC,RHOB,LAMTOR1,TAFAZZIN,HTRA2,RIT1,FIS1,NTRK3 |
| 3.548e-09 | -19.46 | ICAM1 (intercellular adhesion molecule 1) | protein interactions | 3383 | 249 | 113 | 19454 | 5460 |
RPL7A,RPL26,H2BC9,ATP5F1A,EIF3G,RPS3,MSN,IL2RA,DNASE1L1,SLC25A4,RPL13A,RPL22,VIRMA,RPS14,CFTR,IDH2,H2BC11,GIT2,RPL26L1,RPLP0,ARHGEF6,RPL27,H2BC12,CST11,RPL4,RPS15,HSPA5,ATP5MG,MZT2B,GAPDH,CSNK2A1,RPL24,RPS2,LSM3,ALYREF,SYNCRIP,SRP14,RPL12,AIFM1,TES,PRNP,RPS16,RPL35A,TMPO,FAM118B,ILF2,SFXN1,TCOF1,RPL23A,EDA2R,HNRNPK,EIF3E,H2BC14,RPL17,RPS13,RAB11A,CREBBP,SNRPB,H1-1,THTPA,SP1,ICAM1,EIF3K,CYB5R3,MARCHF9,FAU,RPS9,SNRPD1,ACTB,TUBB,RPL35,CLIC4,RPL19,RPL27A,IL2RG,PRDX3,PAK2,ATP5PO,SLC25A3,XRCC5,RPS28,HADHA,PHB2,EMC1,RPL6,IFI16,HNRNPA1,H2BC17,HNRNPD,OCIAD2,PHB1,RPL9,RPL8,RPLP2,SNRPA1,SNRPD3,RAF1,ACTN4,TUBA1A,H1-3,H2BC1,AQP3,RPL18,RPS23,OTULIN,SART3,HNRNPA2B1,PABPC1,RPL31,VDAC1,ANP32B,IFNG,RPS4X |
| 3.553e-09 | -19.46 | Metabolism | REACTOME pathways | R-HSA-1430728 | 2158 | 790 | 10285 | 3229 |
PSMA6,ST3GAL2,CHST7,PCBD1,NDUFAF3,CHPF,ODC1,PYGB,GPD2,SULT1A3,CSGALNACT2,AGPAT5,APOC2,RPL10L,CYP7A1,SGMS1,CA14,PSMC3,ABHD14B,CPNE1,SEM1,NDUFS3,SLCO1B3,PSMB4,CBR3,PCSK9,LHB,CHPF2,CTRB2,PDHA1,RPL9,RPL18,CYB5R3,CHST11,NUDT7,GNB1,ACER3,UBA52,RPL4,RPS23,ENTPD4,NUDT9,DCTPP1,CYP2C18,SLC25A28,VLDLR,STARD3NL,ATP5PB,UGP2,MED9,GNG3,RAP1A,ACOX1,RAB4A,CHKB,CYP2D6,MTM1,ASPA,PGAM1,TPH2,NSDHL,AKR1C1,GLYATL3,IMPA2,PLEKHA8,GBE1,NUP35,HPGDS,DTYMK,SLC25A21,GNB4,RPLP0,FABP12,MT2A,RPS26,RPS17,DIO1,PSMD6,MED29,DPEP3,ADPRM,NDUFV2,PSMB10,ORMDL3,ABHD10,PSMC5,TXN,ACADS,PTS,TTR,PLA2G5,HSD17B1,PSMA3,ATP5F1E,GSTO2,PYGM,PSMB7,INPP5K,PSMD3,FITM1,CHRM3,STK11,ELOVL4,NDUFB6,ATP5MG,GNG2,SMARCD3,PSMD7,SDC2,UGCG,LUM,SLC25A20,FITM2,RPL23,MED27,PHYH,NMRK1,SLC37A4,SGMS2,RPL23A,NUDT18,HS3ST5,GNG11,SLC52A3,CREBBP,SLC2A3,MTARC2,ADH1A,CYP3A43,AASDHPPT,UMPS,ACBD7,GGCT,PSMD4,HSD17B10,OAZ1,ABCB1,MVD,UCK1,RPL15,DBT,RPS28,HDAC3,GMPS,B3GNT2,MTMR2,IDH1,RPS5,COX5A,MED22,ETNK2,NDUFA5,PTEN,SULT1B1,CYP26A1,SAT1,ACSS2,CHDH,ABCC5,RRM1,PNPO,UQCRQ,GNA11,MGST3,RPL37A,PPP1CB,COX14,ELOVL3,RAB14,RPL26,TNFAIP8L3,MT1A,MTF1,PSMD10,FADS2,RPL7A,OSBP,PPAT,PYCR1,PSMD12,HS3ST3A1,RPSA,PTDSS1,MED21,WASL,PDP2,UCP2,RPL27A,CYP11B1,IDO1,SLC35D1,SLC19A2,ABCG2,GSTM5,SRM,ADH1B,B4GAT1,FA2H,NDUFAB1,HMBS,ELOVL7,PIK3CG,RPL26L1,CRAT,ARL2BP,INPP4A,EHHADH,UST,CPT2,RPL31,CERS2,RPL12,UQCR11,KARS1,NOSIP,UBB,GSTT1,TNFAIP8,RPS11,AGPAT1,MTHFS,LBR,ELOVL1,GNG12,HBB,PRELP,PSME1,NUDT5,RPS15,MMUT,NFYA,NT5C3A,GPX4,TAFAZZIN,B4GALT4,PLA2G4B,PIP4K2C,DCTD,HAS3,RPS16,HYAL2,LIAS,GPT,ACADSB,RPL6,ATP5MC1,RPS20,COX7B,RPS27A,PPP1CC,CAV1,DLST,RAB5A,B4GALT1,PGM1,LRAT,HACD3,COX6C,PHKG1,NUDT1,CERS6,CHST9,GPIHBP1,AP2A1,SAR1B,PSMA5,PHKB,GNG10,ATP5F1D,UGDH,CYP1B1,HNMT,PAOX,SIN3A,OXCT1,GPHN,SRD5A3,PGK1,GALC,SLC25A27,STARD7,AIP,COX10,MT1E,NUP107,GUK1,ISCU,AP2S1,CHST2,ACAA2,MSMO1,GLTP,FAU,RPL32,MED23,G6PD,PIK3R3,FIG4,CTSA,ACHE,RPE,EXT1,ACSL4,EPHX1,MED13L,PTGES3,NFYB,HADHA,NDST1,AKR7A2,PSME2,ABHD4,RPL19,TACO1,ACOT6,DNM2,RPIA,PTGDS,APOC4,GPC1,INPPL1,LPCAT3,SLC6A8,NUDT12,PRKCA,AZIN2,CYP2C9,PNPLA8,VAPB,RPS27L,NQO1,SLC6A12,SORD,HSP90AA1,PIK3CA,RPL28,AKT1,VAMP2,GSTK1,GLIPR1,NUBP2,ATP5PF,ST3GAL4,SLC23A2,VKORC1L1,FURIN,CYP4F22,GSTA2,COQ10B,GLYAT,AK5,NDUFA1,SELENOI,NDUFA12,CYP17A1,RPL10,SLC25A12,AMT,RPL22,GDPD3,FBP2,AMACR,LRP10,ADIPOQ,SHMT1,MIR671,HSP90AB1,PIK3R2,NPC2,OAZ2,HADH,LRP12,COX20,PPP1R3C,CHST13,UQCRC2,KCNB1,OAZ3,SLC19A3,CD36,DLAT,FXN,ADO,SLC25A1,RAN,GNGT2,IDH2,AGK,FABP4,DIO2,RPS4X,ORMDL1,COMT,CSGALNACT1,MED31,PRKD3,ALB,PPARA,SCD5,GGT7,TNFAIP8L1,ADCY2,PSMA2,ELOVL6,PNPLA4,TRMT112,ADIPOR1,ETFB,NDUFA4,RGL1,HACD2,PSMD14,SLC25A17,SLC35B3,HSD17B8,IDH3B,CYP3A5,ESYT1,NDUFB7,AZIN1,ADK,CNDP2,RPL35A,GPAM,COX8A,KDSR,GALE,MGST2,CACNB3,GSTM2,CDIPT,GLUL,NDUFA2,GAPDH,ATP5MC3,ISYNA1,CYB5B,TIMMDC1,HSD17B3,MPC1,THRAP3,LDHA,PRSS1,SEC23A,RPL35,FMO1,OAT,COX4I1,NDUFAF2,SPHK2,RPL17,MAT2B,GDE1,CPT1B,CYP4F8,SLC5A6,ARF1,NUDT4,SUCLG2,GLRX,RPS12,UQCRC1,PPM1K,FMOD,EP300,THTPA,NR1H2,ASRGL1,BCKDK,NT5C2,ESD,GNPDA1,RPS14,HEXB,DDAH1,GNAI2,BMP1,CIAO3,NEU1,SLC45A3,MTMR6,DDAH2,CYP4F12,FMO3,CKB,DIO3,GGPS1,RPLP2,ACAT1,RPL8,MAT2A,PLAAT5,SPTSSB,FABP7,HACD1,ACO2,GSTM4,MCAT,CYP2F1,ADCY3,PSMB5,MED30,GSTP1,DEGS1,OCRL,PGS1,PRKACB,B4GALT6,ARG2,NMRAL1,ST3GAL1,TMEM126B,ATP5PD,MED11,AOX1,CERK,SDC4,UGT2A3,MTHFD2L,PSMB2,FOLR2,NUP42,GNPDA2,NDUFS2,GNA14,ACBD6,PPP2CB,AUH,PSMC1,RPS24,SLC2A1,AKR1C2,PFKFB2,RPLP1,UBIAD1,NUP62,RBP2,MARS1,GNG13,LDHAL6B,TXNRD1,B4GALT7,FAH,CMBL,NDUFS6,SC5D,ACOT8,LYPLA1,NDUFC2,AK2,PAPSS2,CA12,PCCB,INPP5E,SLC25A10,SDHC,CYP4V2,RPL39,PDHB,CMPK1,NME2,NUDT3,AANAT,NDST3,MDH1,PHKA1,CIAO1,PDSS2,FBP1,FDFT1,NDUFB10,GYS1,INMT,STXBP1,GSTO1,MIR631,TYMS,CYP27A1,CSNK2A1,PSMB9,NDUFS8,CYP2R1,GCLC,MED17,ENTPD3,GCHFR,PSMB11,HSD17B11,NDUFB4,SLC25A32,GPX2,NUP50,MMACHC,MYLIP,NUDT16,CSNK2B,NUDT19,PPP2R1A,RPS9,HSD11B1,GK2,GNG7,RPS2,G0S2,ATP5PO,SLC6A7,TST,SMPD2,CPTP,SLCO1A2,DCK,CDK8,FAR2,FMO2,MED4,HACD4,PPT1,CRYM,ASMT,G6PC3,UQCRH,RPS13,ADSS2,PLD3,TECR,GSTT2B,SERINC3,RPS29,SDHB,NME1,INSIG2,MID1IP1,PSMB3,ACP6,CHST1,PLCB1,LIPT2,ATP5F1B,GPC4,MMAA,STX1A,HS3ST1,GSTA1,FABP5,CYGB,SNAP25,CYP1A1,STARD4,MT1M,ALOX5AP,GSTM3,ACACA,SACM1L,RPL27,DECR2,PNP,OGN,MED10,LMBRD1,IP6K1,AKR1A1,RPL10A,PC,KCNJ11,PIP4P1,RPL29,CYB5A,CYP39A1,ACOT13,AP2M1,SPR,CACNB2,RPL24,AKR1B1,PYCR2,NDUFB5,COX11,SLC25A14,ETFA,CRYL1,PTPMT1,CYP21A2,ACP5,AMY2B,NDUFAF6,LDLR,POR,DPEP1,CYP27B1,LDHB,CYP11B2,CD38,CHAC2,PLCB2,BPGM,SERINC1,ENO2,MT1X,HILPDA,PPARG,HMGCS1,PIK3R1,RDH11,SLC25A11,IDH3A,COX16,B4GALT3,GLO1,HS2ST1,RPS10,RARS1,GLCE,OSBPL8,PSMD1,CBR4,CYC1,NDUFB8,CYB5R4,PLA2G12A,UGT1A1,ABHD5,PSMA1,PRPS1,RPL13A,NPC1L1,SLC16A1,LIPA,GSTA4,GNMT,PIP5K1A,RPS3,GNG5,SLC25A4,MT3,ENO1,GNPAT,UCK2,B3GALNT1,RPL7,BLVRA,CYB5R1,RPS7,HMOX2,HBA1,NAT2,ALDH1L1,ZDHHC8,PCK2,MTAP,MIR639,SLC6A11,GNAQ,GPX1,VAC14,SLC25A5,RPL3,GNB3,CYP2C8,HEXA,PTGES,NUP37,NDUFAF4,STARD5,EEF1E1,PITPNB,CDO1,NUP153,SP1,PCYT1B,SPTSSA,DBH,STAR,ADIPOR2,CHP1,ATP5F1A,PSMB6,PSMA4,CH25H,PSMC4,RHAG,AHCYL1,PSMB1,TNFAIP8L2,PHYKPL,PLAAT3,GAMT,COX6B1,NME4,CA2,MMADHC |
| 3.584e-09 | -19.45 | VDAC2 (voltage dependent anion channel 2) | protein interactions | 7417 | 388 | 162 | 19454 | 5460 |
ACACA,CYC1,MEST,HSP90B1,GRM2,FGFR1,METTL14,RPA2,JUP,COX6C,CFTR,UQCRC1,UBA52,MPV17,ATG16L1,TOMM20,GPX4,RNF113A,PML,RPA3,MME,UBE2H,CALU,IGF2BP1,NRP1,ATP1A1,DNAJC10,CISD1,ATP1B3,ATP5F1A,RAB2A,SUGP1,VIRMA,DYRK1A,UBE2L3,TECR,UQCRQ,SMURF1,MGST3,NDN,GANAB,RCBTB1,CCNF,UQCRC2,FURIN,SLC25A20,NDUFS3,TMEM205,MTCH2,RPSA,INSIG2,FAM162A,PREB,ATP5PB,MDC1,FKBP8,GALNT2,ATP1A2,EMC2,SEPTIN7,ABCE1,SLC25A11,FAF1,RAB1A,HDAC6,BAK1,DPP4,TSPO,CAV1,ZBTB2,ILVBL,LMAN1,CDK9,MYL12A,FZR1,CD4,COX4I1,SSBP1,AIFM1,CAV2,NDUFA5,PIH1D1,ACAA2,PPT1,MED23,ATP5PO,BET1,MTX2,G3BP2,COIL,GNB4,STX7,ITGAV,RNF11,SSR3,RER1,PHB2,ADRB2,NDUFS2,EMC1,UFL1,HADHA,HSPA8,P4HA2,HDAC5,NMRAL1,JAGN1,THOC6,HSP90AA1,YWHAZ,ATP1A3,PCCB,TOMM40,RFC5,CUL3,HNRNPC,MYC,ESR2,GNB1,ACTB,ATP5F1B,BST2,CYB5R3,DLST,LMBR1L,STX12,NDUFA12,KDELR1,CHMP4C,PDHA1,EZH2,RPN1,FAF2,CYB5R1,TUBA1A,RAF1,TOP3B,PAK6,ATP5F1D,VDAC1,TRIM37,TNF,G3BP1,COX8A,NDUFA4,SLC25A5,BCL2L1,HNRNPD,AGR2,CTNNB1,DDRGK1,RAB5C,MARCHF5,PIK3R1,HSP90AB1,SERINC3,NDUFS8,EGLN3,ATP6V1A,MCOLN1,PHB1,OCIAD2 |
| 3.584e-09 | -19.45 | PSMD3 (proteasome 26S subunit, non-ATPase 3) | protein interactions | 5709 | 362 | 153 | 19454 | 5460 |
SPR,PSMC4,PAAF1,CFTR,UBLCP1,CDC42,SNAI2,GRM2,METTL14,RPA2,HECTD1,HEXIM1,UBE2M,PRPF4,RPA3,BAP1,SQSTM1,DERL1,FBXW7,HSPA5,PSMB2,USP14,AR,ST13,DEPDC1B,FBXO7,SPOP,UBE2H,ATP1A1,PSMA6,CCNF,PTEN,PSMC5,ADRM1,TMOD3,VIRMA,KBTBD4,PSMB9,LBR,TMEM31,RNF181,GNAI3,PSMC3,RAD23B,ZFAND2A,PSME1,MAP1B,HSD17B10,IGF1R,CSE1L,SEM1,PSMA5,HUWE1,FKBP8,VTA1,FBXO25,MEPCE,RPS13,RNF20,MOV10,GAPDH,TPM3,PPIL4,ZFAND2B,PSMD7,CCDC92,USP15,MAP4,PSMB1,TES,FZR1,CDC5L,MRPS23,PTP4A3,PSMB3,EMC9,PSMB7,ARCN1,RPS28,EP300,PSMA3,TXNL1,HSPA8,CRY1,HDAC5,STAU1,UFL1,RNF11,DDI1,PSMC1,CUL3,PSMA4,MYC,BAG3,SNRPB,PSMD1,BRCA1,PSMD14,RIT1,NFKBIA,PRMT5,SNRPD2,RBBP4,TSN,PSMD6,ACTB,PSMD4,ESR2,GNB1,PSMB6,B3GNT2,NAA16,NAA15,SOX2,PPP2R1A,GFPT1,ISG15,CHMP4C,EZH2,TMEM14B,MOB3C,PABPC1,BCL7B,UBE3A,RUVBL2,RUVBL1,HNRNPF,PSMA2,RBBP7,KRAS,EMC8,PSMA1,PSMD12,UBE2A,RPS27A,MARCHF5,STOML2,IFI16,PSMD3,DDRGK1,TRAF6,PSMD10,AGR2,POU5F1,AHSA1,PEX3,RB1CC1,PSMB4,PSMB5,PSME2,CCAR2,DYNC1I2,EGLN3 |
| 3.593e-09 | -19.44 | APC/C:Cdc20 mediated degradation of Securin | REACTOME pathways | R-HSA-174154 | 68 | 45 | 10285 | 3229 |
PSMA3,PSMB5,PSMC4,PSMD3,CDC16,PSMB7,CDC20,PSMB1,PSMB6,PSMA2,PSMB3,PSMA4,PSMB11,PSMC5,PSMB10,PSMA5,PSMD7,PSMD10,PSME1,CDC26,UBA52,UBB,PSMD14,ANAPC16,PSMD12,PSMC1,PSMD1,PSMB2,PSMA6,PSMB9,SEM1,PTTG1,ANAPC4,UBE2D1,PSME2,PSMD6,ANAPC2,ANAPC15,CDC23,PSMB4,RPS27A,PSMD4,ANAPC11,PSMC3,PSMA1 |
| 3.644e-09 | -19.43 | NAPA (NSF attachment protein alpha) | protein interactions | 8775 | 184 | 89 | 19454 | 5460 |
PAK2,EIF4B,BET1,GOSR2,YIPF5,OTULINL,GOSR1,MCMBP,STX7,UNC45A,HSPA8,TMEM185A,BET1L,CCT2,SCFD1,RAB11A,RNF40,STX16,PSMD6,ACTB,TRMT6,SNRPD2,VAMP2,EZH2,CCR1,STX12,RAF1,PPP2R1A,SOX2,KRAS,HNRNPF,ETFA,VAMP8,MAEA,TOP2B,PABPC1,RINT1,STX1A,HSPB1,PRPF19,ATG9A,HNRNPL,VAMP7,STX5,PTP4A2,RPA2,LMNA,USE1,IDH2,SEC22B,CDK7,NAPG,YKT6,HSPA5,RPA3,PGK1,RAB9A,RTN4,STXBP6,SAYSD1,NRP1,VAMP5,AR,GORASP2,ADRM1,VAMP3,PSMA6,SCAMP2,MOB4,STX10,ODR4,TFRC,PSMC3,FURIN,SNAP29,STX11,CTSC,STX8,STX18,SNAP23,AGPAT1,EMC4,ELOC,VTI1B,SNAP25,STX6,PTPN1,MRPS9,RAC2 |
| 3.781e-09 | -19.39 | HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) | protein interactions | 9987 | 345 | 147 | 19454 | 5460 |
EEF2,RPS7,GCLC,ARFGEF1,HGS,EZH2,CHMP4C,PDHA1,EWSR1,RPS24,HNRNPA2B1,PABPC1,LSM14A,UBE2A,SSRP1,HNRNPF,VDAC1,HNRNPA1,DDRGK1,HMGA1,PDIA3,MTRF1,MRPS35,DDX1,HNRNPD,MRPS26,HSPB1,WDR12,EED,PHB1,SRSF1,IFIT2,CHMP2A,DHX15,ADCK1,PAIP1,HNRNPL,WDR77,EIF4B,MAP2K1,NMRAL1,NUP50,EP300,DDX5,SNRPA,NGRN,EXD2,UFL1,SRSF2,HNRNPA0,LZTFL1,STAU1,SNRPB,MTG2,AUH,MYC,APOBEC3B,CUL3,PMPCA,HNRNPAB,CUL2,HNRNPC,SERPINH1,MCAT,DCAF4,BRCA1,FBXW11,RMDN3,TACO1,MTG1,UBE2S,ESR2,MATR3,SNRNP40,EEF1A1,H2AX,METTL15,RAP1A,MRPL11,CCT5,ILF2,NUPR1,CBX3,DHX9,HSD17B10,PPP1R12A,MEPCE,NEDD8,CSNK2A1,COPS5,DPP4,GRSF1,CHCHD1,SNRNP70,PREP,RB1,MRPS9,SSBP1,CD274,SYNCRIP,UBE2G2,ARMC1,MALSU1,RBM42,CAND1,DCUN1D1,FZR1,TOP1,NEK2,CFTR,SF3A1,ATG16L1,ARHGAP1,HEXIM1,HNRNPH3,MTRES1,RPA2,PICALM,METTL14,HNRNPH2,PRKCB,GFM1,RPA3,APMAP,BAP1,EIF4E,ABCC2,HSPA5,TUFM,NONO,NAA50,PTPN11,IGF2BP1,CDKN2AIP,GGCX,UBE2H,PNPO,MRPS16,RC3H2,TXNIP,OPTN,CCNF,PSPC1,ZNF330,NDN,TXN,EIF4H |
| 3.793e-09 | -19.39 | PSMD7 (proteasome 26S subunit, non-ATPase 7) | protein interactions | 5713 | 252 | 114 | 19454 | 5460 |
HSD17B10,PSME1,RAB1A,FKBP8,RPS13,RNF20,MEPCE,DNAJC30,PSMA5,HUWE1,SEM1,PSMB9,TP53,RAD23B,PSMC3,ACTR2,TMEM31,PSMB1,SYNCRIP,PRNP,FZR1,ELOC,USP15,PSMD7,CCDC92,PSMG2,SYVN1,PML,BAP1,RPA3,UBLCP1,PAAF1,CFTR,CCND1,PSMC4,SPTBN1,SF3A1,CDR2,UBE2M,STAMBP,HEXIM1,GRM2,HSP90B1,LMNA,RPA2,PTEN,PSMC5,PSMA6,VIRMA,RPGRIP1L,ADRM1,CHMP5,AR,USP14,RACGAP1,PSMB2,UBE2H,STK24,CCDC22,MRPS16,CISD1,TRIM11,UBE3A,EWSR1,ABCF1,PSMD12,KRAS,PSMA1,PSMA2,ISG15,PPP2R1A,SOX2,SNX20,MOB3C,PSMB5,PSMB4,PSME2,EGLN3,DDRGK1,CTNNB1,YWHAH,PSMD3,MED4,TST,TRAF6,PSMD10,PSMA3,EP300,TRIM5,TXNL1,HTR1A,DDI1,PSMC1,RNF11,MCMBP,UFL1,PSMB3,MED23,PSMB7,SRXN1,PSMB6,PSMD6,FBXO22,MTM1,PSMD4,UFD1,PSMD1,TOMM40,PSMA4,CUL3,MYC,RIT1,PSMD14,BRCA1 |
| 3.793e-09 | -19.39 | ORF7b (ORF7b protein) | protein interactions | 1489675 | 252 | 114 | 19454 | 5460 |
VKORC1L1,STX10,TNFSF15,VAMP3,NAPA,EPHA2,TMEM106C,GORASP2,HMOX2,PTPN11,FLRT3,DAD1,BNIP3L,TMUB1,NAPG,ARFIP1,MAVS,LRRC8D,PSEN2,TM9SF1,LEMD3,GALNT1,ST7,ABHD5,RABL3,FUT8,STX6,LMAN1,TMED9,SNAP25,EXT1,LDLR,XXYLT1,GNPAT,SRPRA,STT3A,CAMLG,COMT,UBE2G2,FITM2,MUL1,TMEM70,TMEM199,FAM20C,FKRP,TUSC3,ELOVL7,ELOVL6,APH1A,B4GALT7,BSCL2,RAB13,CYBRD1,GALNT12,C1QL1,DDR1,LTBR,RUSF1,GLCE,TMEM156,SYNGR3,GPD2,ACVR1,ALG11,CD38,B4GAT1,ALG5,MYRF,LRRC8A,GGT7,LRP12,GPR89A,SEC61B,SCFD1,ZMPSTE24,FAS,STX16,SLC30A5,ENTPD4,TM9SF4,TMED4,STX7,HIGD2A,NT5C3A,GOSR1,TMEM256,JAGN1,IL6ST,LDAH,GINM1,BET1,GOSR2,CYP4F8,VAMP7,PEX13,NEO1,SPINT2,STX5,SNX17,LAPTM4A,TMEM164,DEGS1,TMED7,ACVR1B,SEMA4C,EFNB1,OPA3,GAL3ST1,TMEM87A,TAPT1,STX12,PLD3,SEC61G,PGAP2 |
| 3.809e-09 | -19.39 | positive regulation of gene expression | biological process | GO:0010628 | 1212 | 448 | 18204 | 5365 |
TLR9,PLCB1,ADM2,MIR548C,SYNCRIP,RGCC,LILRA2,MIR21,MIR30B,DNAJC3,MAD2L2,RIGI,PAX6,CLEC6A,UCN,POLR3F,CD36,CD80,RBBP9,MIR33B,IREB2,PRKAG1,RMND1,PNP,CD274,FOXP3,ENO1,HSPD1,UHMK1,LDLR,SF3B4,IFNGR1,TENT4A,FLOT1,PELI1,THRAP3,FOXP1,STOML2,MIR223,FGR,POLR3B,DDX1,FCER1G,IL12B,MMP14,TRAF3IP2,ERP29,TP53INP1,ID4,RSAD2,AGPAT1,IL6,PAIP1,CD86,PADI2,XBP1,TNFSF13,ODAM,GRIA1,MIR206,EIF2AK2,CD14,RLN2,PID1,KIT,IL2,MIR130A,HNRNPAB,AR,TRIM24,SOD1,MSN,JAK2,STAT1,FGF1,MIR125A,TIRAP,KPNA6,LACC1,RAMP3,GSK3A,RAB27A,CD34,ELAVL4,MIR182,CEBPE,LMNA,WNT7A,PPP3CA,VSTM2A,AKT1,IL1B,RPS4X,PRMT5,AGR2,FUBP3,TLR6,RPL26,SMAD4,TANK,ITGA2,EP300,HMX2,IGF1,PDCD10,TCF23,WDR77,PIK3R3,MIR675,EIF3D,SIRT7,CALR,CTNNB1,HYAL2,SHLD1,VDR,TMEM106A,MT3,KLK5,PIK3R1,SETD4,IRF1,PQBP1,CCL1,OSM,AFAP1L2,TLR8,IFI16,NTRK3,NTRK2,NIBAN2,METTL14,EIF2B5,TRUB1,MPV17L2,TLR1,IL15,MIR769,NFE2L2,TICAM1,FGF23,EIF3E,BMPR1A,MECP2,SMARCB1,IL23A,BMPR2,VEGFA,SEMA7A,SLC38A2,MIR29A,EXOSC3,NRDE2,IL18,SRC,ANGPT1,UQCC2,PHB2,CD58,PIK3CG,ATF4,PDE4B,CD200,MIR140,LEP,CD40LG,POLR2G,IL17F,IFNG,APEX1,ROCK1,MEF2A,APOBEC3A,TRAF6,FXR2,MIR183,TLR2,CYP1B1,TICAM2,VAMP3,TLR5,CCL19,TBK1,CYRIB,VIP,IGF2BP1,BMPR1B,CLEC9A,CHI3L1,WBP2,PDE2A,MIR16-1,PABPC1,PLP1,CLU,FGF16,SYK,MIR205,HILPDA,NLRP1,ACVR1B,CD40,BOLL,ATF3,PRDX6,NKX3-1,SGF29,RPS7,FCGR2B,NOG,TESC,ALKBH4,APOBEC3C,STAP1,SPTBN1,CD2,VSIR,SMAD3,MIR101-1,TUSC2,TRMT112,TRIM32,HNRNPD,EIF4A3,KMT5B,PRKAB1,LAMP3,MED23,SELENOK,TFRC,IFIH1,RBM22,IL20RB,ZMPSTE24,RUNX1,MYD88,SMAD2,BRCA1,IL4,MIR149,CD46,APOBEC3F,MIR324,SNRNP70,FAM98A,NLRP9,CD4,RPS27L,CD81,DGCR8,PSEN1,MIR146A,CAV1,TYROBP,MAVS,RAB1A,CD28,MEF2C,SASH3,PDCD5,CCL3,HNF1B,CD83,MIF,IL12A,BCL10,DDT,HTR2A,MIR132,LILRB1,OSR2,CDK1,EIF5A2,ATP6AP2,IL6ST,CSF2,HSP90AA1,NFIL3,IRF3,GPSM3,G3BP1,SPON1,CCL5,AKAP12,DEFB124,TLR3,MYC,FRMD8,HSPB1,PAEP,CIRBP,HNRNPA0,TADA3,SOX9,MAFG,PYM1,DNAJB9,SMAD1,IL5,IRF7,TLR7,MACROH2A1,PRPF19,NR1I2,LTA,IRF8,HGS,MIR511,MAP2K1,TRAF3IP3,OAS1,HNRNPC,PTPN22,DHX9,DKK1,DYRK1A,UAP1,PIWIL2,CCR7,STAT6,KLK3,ISG15,ADTRP,HAND2,SRPK2,KRAS,DPY30,ACTA2,IL1A,MIR144,LRP3,LTB,FGF10,TLE1,NCK1,IL2RG,TRA2A,PLGRKT,MIR106A,PRKCQ,PGR,SP1,MIR212,RBM3,PPARG,PTGER4,RPL23,SFRP4,RAD21,HMCES,KPNA2,C1QTNF1,LUM,SLC6A4,IL34,EGR1,GAPDH,TRIM15,YTHDF2,B2M,IL7,ITK,UPF3B,DROSHA,SRSF1,BAG2,FGF22,SCAMP5,HSPA8,TOMM70,KLF4,PTPN11,CDK6,DDIT3,TRIM27,TLR4,CXCL8,MDM2,IDO1,TP53,TENT5D,VPS72,MITF,IL21,CLEC7A,MIR34A,IL13,GJA1,MIR17,NLRP3,CEBPG,CNTN1,CLDN3,IRF4,CCR2,AIF1,MIR657,PLSCR1,TENT5C,TNFRSF14,SPHK2,USP16,TRA2B,CGAS,OGG1,NLRP2,CITED1,YTHDF1,FGF7,HMGB1,HFE,SH3BGRL,LARP4B,EMILIN1,ITGB8,HINFP,S100A10,HRAS,PYCARD,MIR23A,AGER,LURAP1,MZB1,IL1RAP,BATF,DDRGK1,FGF3,FGF17,POLDIP3,ADIPOQ,TNF,NGRN,CX3CL1,RBPJ,PTGFR,IL10,MIR640,ROCK2,XCL1,FCGR2A,NMBR,TRAF2,MIR145,LY96,TRIM6,EEF2,RPS3,PHB1 |
| 3.949e-09 | -19.35 | Autodegradation of Cdh1 by Cdh1:APC/C | REACTOME pathways | R-HSA-174084 | 64 | 43 | 10285 | 3229 |
PSMD4,UBB,ANAPC11,UBA52,CDC26,RPS27A,PSMA1,PSMD14,PSMC3,PSMD7,ANAPC4,PSMB9,FZR1,SEM1,ANAPC2,PSMD6,PSME1,ANAPC15,PSMB4,CDC23,UBE2D1,PSMD10,PSME2,PSMB3,PSMA6,PSMB2,PSMD1,PSMB6,PSMA2,PSMC5,PSMA5,PSMB10,PSMA4,PSMD12,PSMC4,PSMC1,PSMA3,PSMB5,ANAPC16,PSMB1,PSMD3,CDC16,PSMB7 |
| 3.974e-09 | -19.34 | SNAP47 (synaptosome associated protein 47) | protein interactions | 116841 | 145 | 74 | 19454 | 5460 |
TMT1A,STX8,STX18,RAB3B,KRAS,FKBP8,MTCH2,APOO,DNAJC25,RAB4A,STIM1,RPN1,STX12,CEP57L1,ARL10,PTPN1,RAB35,GJA1,HSD17B11,DNAJC1,ARF6,ECHDC1,CAV1,CNTROB,TMPO,STX6,EGLN3,MARCHF5,RAB5C,SLC25A46,ATG9A,LAMP2,FATE1,LAMP3,INSYN1,ESYT1,AQP2,HAX1,STX1A,PEX3,EXD2,AKAP1,RAB5A,DERL1,RAB9A,OIP5,SLC31A1,NAPG,PXMP2,TOMM20,STX7,TANK,SEC22B,ST7,OTULINL,SEC62,CDC42,SSR1,USE1,APOC2,LURAP1,APOC4,SEC61B,RMDN3,RHOJ,F11R,MGST3,CUL3,VAMP5,RAB11A,RAB2A,RHOB,LAMTOR1,FIS1 |
| 4.045e-09 | -19.33 | regulation of protein localization | biological process | GO:0032880 | 872 | 335 | 18204 | 5365 |
BAG3,CTNNA1,ANP32B,PID1,NDFIP1,TRIM22,GHRL,SNX12,PICALM,RIC3,AR,CARTPT,DLG1,CNR1,CRKL,MSN,ATP5IF1,FIS1,STX7,NR1H2,TRIM29,OS9,MACROH2A1,KDM1A,CHRM1,TTC8,ATP2B4,BCL2L1,CCT2,OR51E2,MMD,TSG101,EDEM1,JAK2,FKBP1A,RER1,SUMO1,BAD,PARL,LCP1,RAMP3,CDK5RAP3,CHGA,GSK3A,PRKCB,PRKCE,VAMP8,AKT1,TGFB3,IL1B,DPH3,GAS8,LMNA,WASL,UBE2G2,WNT7A,PPP3CA,C9orf72,CCT7,CREBBP,B9D1,ADTRP,PFKFB2,LZTFL1,DRD3,GPC1,AGR2,SNX33,IL1A,CHP1,TGFB2,SIRT7,OSBP,TAX1BP3,DKC1,EP300,SVIP,IGF1,FRRS1L,UCP2,PDCD10,ENY2,INPP5E,TRIM8,JAGN1,OTUD7B,SLC1A1,CTNNB1,RAB29,HYAL2,TCAF2,TXN,PPP2R5A,NGDN,MIR148A,SNX3,JAK1,PKIG,HTRA2,PCK2,PLCB1,RBM22,GNAZ,HDAC3,RTN4,ATP2C1,CD81,HADH,LILRB4,MIR146A,PSEN1,DNAJB6,SYT4,SFN,MAVS,SAR1B,EDNRA,USP8,MEPCE,ACHE,IFI27,SIN3A,TYROBP,TP53INP2,VTI1B,CAV3,EFNA5,AP2M1,FKBP1B,CNPY4,SWAP70,BAP1,CD36,HSP90AB1,IL12A,INPP5K,UHMK1,DMAP1,CDK1,TRIM34,PDCD5,RAB9A,AKT2,OPRM1,TMBIM1,CDK5R1,GDI2,GPC4,PARD6A,SNAP25,VEGFC,PRNP,HAX1,BTF3,HSP90AA1,STX8,CLIP3,TRIM68,UBAC2,DPP10,IL12B,MMP14,WWP2,RAB23,ACSL4,ACVR1C,MIR223,KCNB1,GPM6B,CCL5,PTP4A3,CDC42,PPIA,GNAO1,MIEF1,CSNK1E,FERMT2,ERP29,SFRP1,CSK,RSAD2,EFCAB7,IL6,ARFIP1,NLGN2,TLR2,SLC12A2,LMAN1,CD38,CFTR,CD2AP,LAMTOR1,STX6,UFM1,CTSD,TMEM59,VIP,TMEM97,ARF6,C2CD2L,F2,PIAS1,EDEM2,PICK1,NUP62,DNAJC1,NETO2,CDK9,SYBU,SH3GLB1,VAMP2,HCLS1,UBXN2B,P3H1,TMEM231,SRI,GNA11,TESK1,TERT,CHRM3,CACNB4,DERL2,CTDSPL2,VPS28,EPHA2,HFE,RAB11B,RHOU,RAB14,CDK5,GOLPH3L,STX1A,NSFL1C,ORMDL3,RANGRF,ABHD17A,ZDHHC8,HRAS,STK11,CCT8,PKIA,TRIM5,FBXW7,NKX3-1,HDAC6,TRIM46,OAZ2,PRR5L,SMAD3,XPO1,NDUFAF2,ROCK2,ACTB,SPTBN1,DDRGK1,SLC7A11,APBB3,ADIPOQ,TNF,TRIM6,RAB11A,SELENOK,ERLEC1,TFRC,UBE2L3,RHBDD3,CCN3,GLUL,RAP1A,SESN2,JUP,CPLX1,YWHAZ,RHOG,SUFU,RAN,PIK3R1,PIK3R2,STOM,CD247,CAMK1,UFL1,SLC16A1,TCP1,CCT5,TOMM7,PPARG,SCFD1,CLSTN3,CHCHD4,UBL5,LGALS3,BNIP3L,NF2,LYPLA1,VRK1,SRC,STAC3,DAG1,PTPN1,ANGPT1,HSPA8,UQCC2,WRAP53,PPID,KCNJ11,RAC2,TM9SF4,CD200,TRIM21,LEP,SQSTM1,LRRC8A,TLR4,TOMM70,PTPN11,HUWE1,SUMO3,VCPIP1,TMEM30A,IFNG,PGRMC1,DYNLL1,PIK3CA,TIAM1,MDM2,VPS4A,UBE2D3,OAZ1,IL13,HPCA,TNFAIP6,STX10,OAZ3,NEO1 |
| 4.055e-09 | -19.32 | CFL1 (cofilin 1) | protein interactions | 1072 | 331 | 142 | 19454 | 5460 |
HSPA8,COX17,DDX39B,SNRPA,PEBP1,TMEM106B,CSRP1,LYPLA2,UFL1,PPP1CB,EIF4B,PIH1D1,AKR1A1,CKS2,ACAA2,SRXN1,ESR2,TAGLN2,SSH3,DYNLL1,ACTB,TAB1,BTF3,JPT1,AK3,UFD1,CAPG,ACO2,MYC,CUL3,LDHB,FIS1,SERPINH1,FAS,YWHAZ,TESK2,RAD21,UFM1,G3BP1,KRAS,TRIM37,SOX2,ISG15,TOP3B,RAF1,B3GNT2,GPT,MTA2,EZH2,PIR,NGB,NME1,CHMP4C,EED,FAHD1,FOLR1,FBXO31,PHB1,FBXO32,PPIA,EGLN3,TRIM15,HNRNPA1,YWHAG,CTNNB1,DDRGK1,EIF3D,CRIP1,PRDX1,DCAF4L2,WWP2,COTL1,AGR2,RNF113A,RTN4,SOD1,RPA3,DVL2,BAP1,TXNDC17,PML,HSPA5,FBXW7,CFTR,UBA52,HEXIM1,UBE2M,LMNA,RPA2,GRM2,FGFR1,METTL14,PTEN,ACAT1,CCNF,ENO1,ZBTB33,CTTN,SH3BGRL,SMURF1,ROCK1,VIRMA,SRC,LDHA,CFL2,FBXO7,USP14,CAP2,CDC73,ATP1A1,UBE2H,MAP1B,ARF4,FBXO25,MEPCE,PSEN1,RIGI,HSPE1,EEF1A1,H2AX,SOD2,TNFAIP8L1,TFCP2,DXO,ACTR2,CAPZA2,DSTN,MTAP,TES,CD274,ACTA2,TMPO,CDK9,MBD5,KCTD15,FZR1,HDAC6,CD81,GAPDH,DPP4,TESK1,NME2 |
| 4.055e-09 | -19.32 | TACO1 (translational activator of cytochrome c oxidase I) | protein interactions | 51204 | 331 | 142 | 19454 | 5460 |
MRPS25,MRPL16,MTG2,AUH,PYCR1,PMPCA,HNRNPAB,PARL,NDUFAF4,ATP5F1B,MRPL23,SF3B4,MRPL13,DLST,MTG1,CCDC90B,MFAP1,NDUFA5,MRPS18A,ATP5PO,NDUFAF3,MRPL12,TIMM29,MRPS7,HSCB,NDUFS2,ATP5IF1,SAT1,NGRN,EXD2,MRPS26,MRPL18,RHOG,MRPL9,NDUFV2,MDFI,CLPX,MTRF1,MRPS35,STOML2,NDUFS8,RMND1,COX14,HNRNPL,LYAR,GATD3,PHB1,NDUFA12,NDUFS6,PDHA1,CSNK1E,HSDL2,ETFB,MRPS17,HNRNPDL,IMMP2L,ETFA,KGD4,HINT2,PDIA6,MRPS11,COX8A,HSPD1,RINT1,OAT,UBE2H,DNAJC19,MECP2,MRPS16,TRIM23,TUFM,NDUFAF2,PYCR2,PPP1R10,MRPS28,CAB39,TRIM27,ACAT1,MRPL53,CTTN,MTRES1,MRPS34,TOX4,QRSL1,MRPL10,NDUFAB1,SEC22B,CRYZ,MRPL20,POLDIP2,PDHB,MRPL17,NME4,MRPL41,MRPL40,TWNK,DLAT,GFM1,PRPF4,TMEM70,CHCHD1,PPIL4,TMA16,GAPDH,GRSF1,COX5A,ATP5MG,DBT,ATP5PD,MRPL24,MRPS23,MRPL50,SSBP1,MRPS9,AIFM1,COX4I1,ALYREF,GFM2,TAF2,MRPL49,MRPL51,DDX42,NDUFS3,AURKAIP1,PPIF,METTL15,BCS1L,ATP5PB,MRPL47,NDUFA2,MRPL11,MRPS18C,FASTKD5,MRPL22,PDE12,MRPS33,MRPS18B,THG1L,HSD17B10,MRPL52,ATP5PF,SFXN1 |
| 4.093e-09 | -19.31 | Defective CFTR causes cystic fibrosis | REACTOME pathways | R-HSA-5678895 | 62 | 42 | 10285 | 3229 |
UBA52,RPS27A,PSMD4,UBB,ERLIN2,PSMD14,PSMC3,DERL2,RNF5,PSMA1,PSMB9,SEM1,PSMD7,PSME2,PSMD10,PSMD6,PSME1,PSMB4,PSMD1,PSMB2,PSMA2,PSMB6,PSMB3,PSMA6,PSMA4,PSMB11,PSMC5,PSMA5,PSMB10,ERLIN1,PSMB5,PSMA3,PSMD12,ERLEC1,PSMC4,PSMC1,CFTR,PSMD3,PSMB7,OS9,DERL1,PSMB1 |
| 4.139e-09 | -19.30 | NUDT21 (nudix hydrolase 21) | protein interactions | 11051 | 354 | 150 | 19454 | 5460 |
BRD3,CLP1,MIR34A,SNRNP70,SHC1,ESYT1,HDAC6,PPIL4,CD81,ERCC3,TLE1,LMAN1,MIR429,FUNDC2,TMPO,CDC5L,CAND1,FZR1,TOP1,MIRLET7G,MIR25,CEBPG,MIR106B,TAF2,DDX42,MIR17,MIR20A,DISC1,MIR15A,CD2BP2,RPSA,MEPCE,MIRLET7C,MIR16-2,MDC1,SEM1,DYNC1I1,HUWE1,TOLLIP,RAB27A,RPL23A,FAF1,UBE2H,NIF3L1,MECP2,MIR145,RC3H2,TRIM23,NTAQ1,NONO,AR,SMURF1,PPP1R10,SRPK2,VIRMA,EIF4H,TRIM27,ZNF655,CCNF,MIR16-1,RPS3,PSPC1,CTTN,HEXIM1,LMNA,RPA2,P3H1,TOX4,SIPA1L1,CDC42,MIR1-2,MIR34B,MIR29A,BCL6,MIR107,HDAC3,MIRLET7I,MIR34C,RPA3,MIR10B,BAP1,MIR205,MIR221,MIR1-1,MIR140,DDX23,CRTAP,MIR31,MIR29C,HNRNPA1,DDRGK1,TRA2A,WWP2,NDC80,MIR143,OCRL,WDR82,EED,RPLP1,MIR214,MIR141,FOLR1,PHB1,MIR7-2,POLR2C,RPL18,EZH2,RAF1,TOP3B,CSNK1E,CBLL1,DHX16,KRAS,MIR155,MIR206,FAM76B,EWSR1,PDIA6,TRIP4,MIR9-2,MIR363,RIT1,ATG3,S100PBP,BTF3,MYC,PYCR1,CUL3,PAPOLA,MIRLET7D,ESR2,TNPO3,MIRLET7B,KLC2,NUFIP2,MFAP1,MYL6,PIH1D1,MIR106A,HSCB,PRCP,PTN,UFL1,FXR2,EEF1G,STAU1,SF3B1,YAF2,PMAIP1,EP300 |
| 4.172e-09 | -19.29 | DDI1 (DNA damage inducible 1 homolog 1) | protein interactions | 414301 | 65 | 41 | 19454 | 5460 |
MAPK10,TRAF2,PSMC4,PSMB3,OGFOD3,SDS,PSMC3,RTF2,PSMB7,PSMA3,DVL2,SFXN1,PSMC1,DDI1,PSMD12,PSMA1,PSMA5,PSMA2,UBE2K,PSMD1,CCL28,RALGAPA2,PSMD3,PSMB2,PSMA4,USP2,PSMD7,PSMD14,PSMC5,GSK3A,PSMB1,CETN3,CYGB,PSMA6,PSMB5,PSMB4,RPP25,PSMB6,PSMD4,PSMD6,ADRM1 |
| 4.209e-09 | -19.29 | Selenoamino acid metabolism | REACTOME pathways | R-HSA-2408522 | 121 | 69 | 10285 | 3229 |
RPL6,RPSA,RPS20,RPS16,RPS24,INMT,RPL32,FAU,RPL3,RPL35A,RPL24,RPL7A,RPL28,RPL23A,RPS14,RPLP2,MARS1,RPS5,RPL8,RPL15,RPS26,RPS28,RPS17,RPS4X,RPLP1,RPLP0,RPS29,RPL13A,EEF1E1,RPL10L,RPS13,RPS27A,RPL27A,HNMT,RPL12,RPL18,RPL31,RPL9,RPL22,RPS3,RPL17,TXNRD1,RPL10,RPL35,RPL26L1,GNMT,RPL19,RARS1,RPL23,RPS15,RPL10A,RPL29,RPL26,RPS27L,RPS7,RPS10,RPL39,RPL4,RPS2,RPL27,RPS12,RPS23,RPS11,RPL37A,KARS1,RPS9,PAPSS2,RPL7,UBA52 |
| 4.210e-09 | -19.29 | Regulation of ornithine decarboxylase (ODC) | REACTOME pathways | R-HSA-350562 | 52 | 37 | 10285 | 3229 |
PSME1,OAZ3,PSMB4,PSMD6,PSME2,PSMD10,NQO1,PSMD7,SEM1,PSMB9,PSMA1,OAZ2,PSMD14,PSMC3,PSMD4,OAZ1,PSMB1,PSMB7,PSMD3,PSMC4,PSMC1,PSMD12,PSMA3,PSMB5,PSMB10,PSMA5,PSMB11,PSMC5,PSMA4,ODC1,PSMA6,PSMB3,AZIN1,PSMB2,PSMD1,PSMA2,PSMB6 |
| 4.213e-09 | -19.29 | GDP binding | molecular function | GO:0019003 | 75 | 47 | 18094 | 5411 |
RAB31,RAB9A,MRAS,DIRAS3,RAB3B,RAP2A,UCP2,HRAS,RALA,SRP54,DIRAS2,TRIM23,RAB22A,RHOB,RIT2,NME2,RAP1B,RAB9B,KRAS,RAP2B,RAP2C,RALB,GNAI3,RAB29,ARF6,RAB5A,RASL12,RAB8B,RAP1A,DIRAS1,RIT1,RAB2A,ERAS,RERG,RAB11B,RAB28,MIEF1,RAB4A,RAB27A,RHEB,SUCLG2,RAB18,RAB35,RAB5C,RAN,RRAS2,RAB14 |
| 4.228e-09 | -19.28 | ribonucleoprotein complex biogenesis | biological process | GO:0022613 | 456 | 192 | 18204 | 5365 |
NOP9,NLE1,DDX23,WDR12,WDR55,RPL35,PRKRA,RRP7A,ZNHIT3,PTGES3,GEMIN7,SRSF1,EMG1,SNRPB,SF3B6,RPS15,IMP3,USP39,RBMX2,RPL35A,UTP25,EIF3E,NOB1,MPV17L2,RPS12,LSM6,RPS11,EXOSC3,CELF6,DROSHA,RPS5,SUV39H1,DDX46,UTP15,ISG20L2,RAN,KRR1,EIF3K,RPP25,NOP16,RPS24,XPO1,NGRN,EIF1AX,SF3B1,PNO1,RUVBL1,TMA16,CINP,MRM2,TRMT112,TAF9,GLUL,EIF4A3,RSL24D1,NOC4L,MAK16,BRIX1,MALSU1,NOL7,RPS7,PPAN,EIF5B,RBM5,SNRPD2,ZNF622,RIOX2,MRTO4,ZNF593,GCFC2,RPF2,TFB1M,CD2BP2,RPL6,PIH1D1,PRPF18,RPS13,RPS16,SNRPD1,PRPF31,C1D,TSR3,RPS28,XRCC5,TXNL4A,UTP23,RPL7L1,RPS14,DDX42,RNASEL,RPS17,SNRPB2,DDX1,PELP1,POP5,SLU7,AGO1,DDX39B,NOP58,RPL23A,UTP6,RCL1,MRPS7,SNIP1,SRSF12,TRAF7,SMN1,PWP2,EIF2S2,SF3B4,LUC7L3,TSSC4,HSP90AA1,FCF1,LYAR,KHDC4,NOA1,RPS23,RPLP0,SRSF10,SURF6,RUVBL2,RPS9,RBIS,RPL7A,HSP90AB1,EXOSC1,MPHOSPH10,RPL26L1,NGDN,RPL10,NOPCHAP1,MPHOSPH6,RBM34,MTG2,RPS27L,SNRPG,YBEY,WBP11,RPL10L,EIF3D,WDR77,POP7,GTF2H5,GEMIN8,RPSA,SRPK2,PAK1IP1,DKC1,SNRPD3,LTO1,LSM2,RPF1,EIF3J,NOP53,EIF2D,DHX9,NPM3,CLP1,RPL26,ZNHIT6,ISG20,METTL15,PRMT5,LSM4,RPS4X,SF3A1,EXOSC8,TSR2,COIL,FTSJ3,PRPF19,NHP2,BUD23,SNRPA1,METTL25B,ABCE1,SNRPE,SRFBP1,EIF3G,WDR3,SART3,AATF,RPL27,NSA2,RIOK2,RPL7,EXOSC4,RRN3,SF3B5,IMP4,DICER1 |
| 4.307e-09 | -19.26 | SPRING1 (SREBF pathway regulator in golgi 1) | protein interactions | 79794 | 258 | 116 | 19454 | 5460 |
RWDD4,RAB18,SLC35A2,ADO,SEMA4C,EMC8,UBE3A,SLC39A7,ZC3H7A,PLSCR1,CYB5B,CLDN12,PGGT1B,PARP11,TLNRD1,PDHA1,OS9,CPLX3,MEAF6,IGBP1,AZIN1,MED4,NT5C2,HNRNPA1,SAV1,SKP1,LYSET,RER1,UFL1,MED13L,JADE1,DDX5,ATP2C1,FAM8A1,VPS18,RBM18,PAK2,PTAR1,RRAGA,MTF1,PRKAB1,CHP1,RABIF,CHCHD3,POLR2B,TP53TG5,TAMM41,CAVIN2,SLC30A7,CPSF1,VDAC2,PHF12,LORICRIN,SLC15A2,HTRA2,SLC7A11,ATP1A3,TAFAZZIN,MPC1,CFAP20,RIGI,RNF20,ERLEC1,REXO2,HSD17B10,EMC2,UNC50,CLPB,PQBP1,GLUL,SDHAF1,SOD2,TP53,DKC1,SELENOI,DERL2,NKAP,HTRA1,LDLR,SLC39A10,UBP1,TIMM8B,SLC35A1,CENPP,TCEANC2,UGP2,NF2,HDAC3,SPCS2,GPX4,DLAT,SYVN1,ELOF1,FLCN,DCTN6,ORC6,GID4,ACACA,TIMM23,HACD2,ARHGAP1,ACP2,DYRK1A,TECR,VKORC1L1,TRIM54,EIF2S2,CAB39,RBM7,ATRAID,SPOP,SNX14,NCAPG2,SLC25A1,VPS39,SUGP1 |
| 4.352e-09 | -19.25 | DHX15 (DEAH-box helicase 15) | protein interactions | 1665 | 468 | 189 | 19454 | 5460 |
AR,DNAJC8,PPP1CC,USP14,TUFM,RUNX1,DEK,RPL22,VIRMA,YES1,TMOD3,NDN,MSN,PTEN,TRIM24,GSK3A,EIF4A3,ENO1,CCNF,RARS1,GRM2,PTP4A2,LMNA,CDK7,FUT8,SF3A1,NF2,TMEM126B,PRPF4,SIRT7,RPA3,KIAA1143,HDAC6,EMC4,NFKB1,MOV10,RCHY1,PTPN1,RPL12,TOPORS,ILF2,CD2BP2,LBR,MAP1LC3B,CCT5,FBP1,RIGI,HAPSTR1,NKRF,ILK,RIT1,BRCA1,RBM15B,CUL2,CUL3,ACO2,NDUFAF4,SNRPB2,SNRPD1,SNRPD2,RAN,RNF7,AGGF1,PPP1CB,ALKBH3,PSMC1,NSFL1C,MCMBP,PSMD10,TRA2A,HNRNPA1,PRPF19,SRSF10,NOP58,PHB1,SNRPE,POLR2C,SF3B5,CHMP4C,EZH2,PPP2R1A,RAF1,EIF2D,UBE2A,SRSF7,PCNA,TRIP4,ZYX,HSPD1,UBE2H,ATP1A1,RC3H2,SPOP,SUGP1,MAT2A,RPF2,SRPK2,ADRM1,GCFC2,SF3B6,TFIP11,HEXIM1,RPA2,POLR1D,HSPA5,MARS1,RNF113A,PML,DDX46,BAP1,MAP4,SNRNP70,ELOC,API5,CD81,CSNK2A1,COPS5,USP3,RBM17,KARS1,CDC5L,TMPO,DKC1,NKAP,FZR1,CAND1,PREP,SYNCRIP,NUPR1,DDX42,TP53,RRM1,KBTBD4,CAPZA1,MEPCE,HNRNPK,PSMA5,SNIP1,PSMD14,SNRPB,UFD1,BTF3,PSMA4,SFN,MYC,PSMD6,MATR3,SF3B4,CMTR1,PIH1D1,TRMT112,MTF1,STAU1,UFL1,DDX5,EP300,HDAC5,SF3B1,HSPA8,SNRPA,DDX39B,YWHAB,MAGOH,HSPB1,PEX3,DDX1,AGR2,DDRGK1,YWHAG,WWP2,GSTM3,IFI16,SNRPD3,SNRPA1,HNRNPL,EED,SRSF1,RBM5,TAF10,SMNDC1,ISG15,SOX2,HNRNPDL,KRAS,PSMA2,HNRNPF,EWSR1,PABPC1,RPL31 |
| 4.393e-09 | -19.24 | regulation of MAPK cascade | biological process | GO:0043408 | 669 | 266 | 18204 | 5365 |
EPHA2,CD40,RGS2,FGF7,HMGB1,FGF16,SYK,MIR205,HRAS,MIR23A,PYCARD,AGER,DUSP10,STK38,TRIM5,ATF3,EMILIN1,FBXW7,ZDHHC17,FCGR2B,RAF1,CX3CL1,MIR24-1,DUSP22,ROCK2,MAP3K11,ALKAL1,FGF3,FGF17,LBH,ADIPOQ,TNF,EDA2R,RPS3,PHB1,DUSP1,AVPR1B,RAP1A,TRAF2,MIR145,TRAF6,GADD45A,FKTN,MIR181D,LAMTOR1,PRKCA,DUSP9,DDR1,DIRAS1,CCL19,ZNF622,NHERF1,NPSR1,RELL1,PSMD10,MAP2K6,CHI3L1,DUSP6,TBC1D10C,MIR424,NPY5R,DRD1,GHR,ADRA1A,SRC,ADORA1,FGF22,DAG1,PTPN1,ANGPT1,PRDX1,LAMTOR3,P2RY1,FGFR1,ACKR3,PRDX2,RB1CC1,PIK3CG,LEP,TLR4,RNF41,PHB2,PTPN11,ICAM1,STK4,DOK5,MIR133B,PAFAH1B1,SDCBP,GPR37,TIAM1,LPAR1,PDCD4,ROCK1,AVPI1,SYNJ2BP,MAP3K3,GPNMB,RELL2,YWHAZ,OSM,TNFAIP8L3,RAP2A,PIK3R2,PAQR3,OPRK1,MIR218-1,NTRK3,LMO3,PPARG,NTRK2,MIR503,FGF23,IL34,C1QTNF1,EPO,TPBG,NF2,LAMTOR2,EZH2,CHRNA7,VEGFA,SEMA7A,DKK1,TGFB3,IL1B,ZMYND11,WNT7A,PDE8A,PTPN22,SOX2,HAND2,SMAD4,ADRB2,GREM1,DRD3,PRMT5,DUSP26,TLR6,CCR7,CRYBA1,DUSP3,IL1A,MAP2K3,TGFB2,PAK6,IGF1,NOTCH2,SPRED1,PDCD10,ACTA2,SPRED2,TMEM106A,MT3,FGF10,CTNNB1,GH1,HYAL2,GSTP1,FAS,EIF2AK2,GNAI2,KIT,ANKRD6,ADRB3,PROK1,MIR20A,GHRL,CCL21,AR,CARTPT,SOD1,DIRAS2,DLG1,CRKL,IGBP1,MIRLET7B,LTBR,PAK2,MIR221,FGF1,PLA2G5,TIRAP,CAV2,RIT2,NRP1,MIR200C,GRAP,NLRP6,JAK2,COPS5,DEFB114,RAP1B,IGFBP4,RAMP3,DVL2,CDK5RAP3,SHC1,CCR1,MAP2K1,PRKCE,REN,INPP5K,DDT,HTR2A,TPD52L1,ATP6AP2,CCL3,MIF,OPRM1,GPR37L1,OR2AT4,PAK5,STK3,TRAF7,GRM1,SPRY1,BTN2A2,ADRB1,GRAP2,MAP3K12,AKAP12,TLR3,EPHA4,MIR185,DOK6,DNAJC27,CDC42,PPIA,GADD45G,DUSP19,FERMT2,ERP29,MYC,FLCN,IGF1R,MIR126,CSK,NDST1,IL6,PEBP1,MYD88,GADD45B,GLIPR2,PLCB1,TLR9,HDAC3,CNKSR3,TNIK,CD4,MIR21,CD81,LILRB4,MIR519D,ARL6IP5,IGFBP3,SEMA4C,GPBAR1,TAB1,DSTYK,DOK4,CAV1,MEF2C,CAV3,LPAR2,CD36 |
| 4.428e-09 | -19.24 | Regulation of APC/C activators between G1/S and early anaphase | REACTOME pathways | R-HSA-176408 | 81 | 51 | 10285 | 3229 |
PSMC5,PSMB11,PSMB10,PSMA5,PSMA4,PSMB3,PSMA2,PSMB6,BUB3,CDC20,PSMB1,PSMD3,CDC16,PSMB7,PSMC4,PSMA3,PSMB5,PSMD14,UBB,CDC26,UBA52,CDK1,SKP1,PSME1,PSMD10,PSMD7,PSMA6,MAD2L1,PSMB2,PSMD1,CCNB1,PSMD12,PSMC1,ANAPC16,PSMA1,PSMC3,PSMD4,CCNA2,ANAPC11,RPS27A,PSMD6,ANAPC2,CDC23,PSMB4,ANAPC15,PSME2,UBE2D1,ANAPC4,PSMB9,FZR1,SEM1 |
| 4.596e-09 | -19.20 | BAG6 (BAG cochaperone 6) | protein interactions | 7917 | 430 | 176 | 19454 | 5460 |
FZR1,MCL1,CD274,IER3,USP15,ZFAND2B,PDE12,KPNA2,TGFBR2,RAB13,TRAFD1,MAP1B,PAQR9,CERK,FURIN,CDK8,TFCP2,ARPC3,KBTBD4,UBL4A,CDK4,INSIG2,MTCH2,TP53,CTSB,TAC1,CHMP5,SEC61A1,CSNK2B,SGTA,ABCG2,ZBTB38,PTTG1,CALU,DNAJC5,PSMB2,AKT1,TOMM20,CLU,HSPA5,BAP1,HEXIM1,SAMM50,CXCL8,CDC42,PNPLA8,RAB1B,STX5,REG1B,POU5F1,WWP2,FKBP2,CDK5,TRIM21,EWSR1,TRIM11,NCR3,KLHL12,KIF2A,PPIL3,HEXA,ESR2,REEP3,PSMD4,FBXO22,RAB9B,GTF2F2,LMBR1L,FIS1,PDF,SERPINH1,PSMD14,CCNQ,APOBEC3B,MYC,CDKN3,SRSF2,RNF5,HSPA8,EP300,AKAP1,RAB5A,PEBP1,SDC2,CTBP1,PPT1,GTF2IRD1,GLRA2,MDM2,ZBTB2,PRNP,DERL2,TES,LDLR,RB1,PWP2,AIFM1,EEF1AKMT3,RAB3A,SPP1,PSEN1,SMN1,HUWE1,SEM1,RNF115,HAPSTR1,FAF1,RAB1A,TCOF1,PPP4C,UAP1,HSPA13,MAP1LC3B,VIRMA,RAB14,NR1H2,TRIM27,PELP1,STUB1,STK11,NRP1,TXNIP,FBXO7,AR,MRPL17,B2M,TTR,DESI1,SYVN1,MAVS,PRIM2,MEST,OXSR1,PDCL,METTL14,GRM2,PRMT2,PSMC4,WDR83,EGLN3,ERLIN1,POLR3F,TSG101,MED4,HNRNPD,VPS26A,CHN2,ACVR1B,HECTD3,GADD45A,RNF126,RPN1,VAMP2,RAB6B,FAF2,ERLIN2,FZD4,SEC61B,NTRK3,FAS,SRGN,USP13,RAB11A,CDSN,PTN,RP2,CRY1,RLIM,ANXA7,MED23,VAPB,RFXANK,CDKN1A,ETF1,RAB6A,NPY |
| 4.601e-09 | -19.20 | NDUFB5 (NADH:ubiquinone oxidoreductase subunit B5) | protein interactions | 4711 | 115 | 62 | 19454 | 5460 |
B4GAT1,NDUFAF4,PARL,ITM2A,LAMTOR3,UQCRC2,PSMG3,NDUFB7,KDSR,NDUFB6,NDUFB10,FTL,LPAR1,SLC25A51,EMC1,NDUFS2,HSCB,NDUFC2,TMEM126B,TMEM185A,TACR1,RPA3,SLC25A3,NDUFA5,COX6C,RPA2,NDUFAF3,MPV17,TIMMDC1,NCALD,OPRL1,NDUFS8,PRNP,HNRNPL,NDUFA1,ATP6V1A,FUT1,SYNCRIP,AIFM1,NDUFB8,MRPS26,NDUFV2,FAM174A,COX7B,DNAJC30,ATP5F1D,SFXN1,NDUFA4,GPR34,NDUFA12,CRELD1,AQP3,NDUFS3,SCAND1,NDUFS6,YIPF3,NCSTN,DDX39A,CENPM,MTCH2,ATP5PB,MARCKSL1 |
| 4.604e-09 | -19.20 | COQ9 (coenzyme Q9) | protein interactions | 57017 | 217 | 101 | 19454 | 5460 |
COMT,SDHB,COQ8A,ACSL4,COX20,RPL35A,FUNDC2,PRELID1,ATP5PD,COX5A,MOV10,TMEM70,TMEM11,SFXN1,ATP5PF,SLC25A11,SLC25A10,EMC2,GNG5,CLPB,SLC16A1,CHDH,ADIPOQ,GALNT2,RDH11,FKBP8,TP53,MTCH2,ATP5PB,COMTD1,SNAP29,BCS1L,TMEM205,GLRX5,HINT3,COX19,NDUFS3,DHRS7B,SLC25A24,UQCRC2,PTPMT1,CYBC1,SLC25A4,CPT2,ROMO1,IDE,GSTK1,NDUFAF2,SLC25A1,CISD1,DNAJC19,ORMDL1,TEX264,MAIP1,MAVS,POLDIP2,TIMMDC1,COQ8B,COX6C,TIMM23,ACACA,TRAF3IP3,RAB35,HEBP1,AGK,NDUFS8,STOML2,CLPX,RAB32,SYNJ2BP,ACTL6B,PPM1K,CHCHD2,HSDL2,DCAKD,CYB5R1,CTSA,PTRH2,CYB5B,CYB5R3,TIMM21,TAMM41,NDUFAF4,CYB561D2,PMPCA,COX11,TOMM40,FIS1,BAX,ATP5MK,HSDL1,ATP5F1E,ATAD1,NDUFS2,EHHADH,TOMM22,CTXN3,NDUFAF3,ATP5PO,NDUFA5,SLC25A3 |
| 4.678e-09 | -19.18 | rev (Rev) | protein interactions | 155908 | 306 | 133 | 19454 | 5460 |
EMG1,DDX5,CXCR4,DDX39B,SRSF2,NUP62,MFAP1,USP39,SMU1,RAN,NFKBIA,FAU,ERH,TNPO3,APEX1,ACTB,LGALS3,SNRNP40,TUBB,MATR3,MCM3,CPSF2,PRPF31,HNRNPC,PRMT6,TMED4,HNRNPAB,DNAJB6,THOC6,RPS5,RTCB,EWSR1,PPAN,ABCF1,PABPC1,HNRNPA2B1,ANP32B,HNRNPDL,RPS27A,RPS4X,FEM1C,RUVBL1,NUP42,HNRNPF,TUBA1A,NUP153,RANBP1,ANP32A,TRMT1L,SNRPE,RPS23,TUBB4B,SRSF1,SNRPA1,SPTAN1,NOP58,HNRNPA1,XPO1,PPIB,RPL6,PRPF19,DICER1,NQO1,RPL23,HNRNPD,HAX1,DDX1,HNRNPH2,RPL27,WDR3,SPTBN1,SF3A1,PRKCA,HNRNPH3,HSP90B1,LMNA,CDK1,SRP54,EIF2S2,PRKRA,MRPS28,CSNK2B,RTRAF,LIG3,TUBA1B,PSPC1,UBB,CSTF3,KPNA6,NONO,RPS17,H2BC9,SUB1,IGF2BP1,EXOSC1,DHX9,RPL3,SNRPG,PTGES3,H2BC14,RPL17,HNRNPK,KPNA2,HUWE1,EEF1A1,MRPL11,TP53,RPSA,H2AJ,ILF2,IK,KRR1,ALYREF,RPL32,SYNCRIP,MRPS9,SSBP1,NOP9,CDC5L,RBM42,TMED9,RPL35A,GAPDH,MPG,CSNK2A1,ERCC3,CALR,MOV10,FBXO34,RPS2,KPNA1,SNRNP70,CHCHD1 |
| 4.807e-09 | -19.15 | ATP1B3 (ATPase Na+/K+ transporting subunit beta 3) | protein interactions | 483 | 209 | 98 | 19454 | 5460 |
BTN2A2,DPP4,COX5A,PTP4A3,ARL6IP5,RAC2,COQ8A,FURIN,NDUFS3,CCDC47,ATP5PB,MTCH2,NDUFA2,RPL17,HSD17B10,RAB1A,SFXN1,ATP5PF,ATP1A1,NRP1,PEA15,SNX5,RPL26,DNAJC5,CNTNAP1,RPL22,VIRMA,RHOJ,CPT2,ACAT1,VAMP3,RPL26L1,CHPF2,CYC1,ACACA,RPA2,FGFR1,TMX4,STOM,CDC42,HSPA5,RTN4,RPA3,FADS2,MYH2,ARMC8,RHOG,FAM241B,SLC25A28,BPNT2,ATG7,FAM241A,SYNJ2BP,EGLN3,PXYLP1,RAB1B,RHOH,RPLP2,PHB1,ITGB5,NDUFA12,RND3,CYB5B,TUBA1A,EEF2,SUPT5H,E2F4,ANP32B,G3BP1,VDAC1,SEMA4C,EWSR1,EFNB1,BAALC,NTRK3,NLRP3,ATP1A3,CGRRF1,BRCA1,RHOB,TOMM40,NDUFB7,TM9SF4,RAB11A,RPL10,PSMD6,RPL35,RPS9,LMBR1L,VDAC2,ACAA2,CTXN3,EMC1,ADRB2,NMRAL1,HSPA8,PMAIP1,PEBP1 |
| 5.007e-09 | -19.11 | ARHGAP1 (Rho GTPase activating protein 1) | protein interactions | 392 | 220 | 102 | 19454 | 5460 |
MARS1,SYVN1,DERL1,RAB9A,RPA3,ARL15,RPA2,RPRD1B,SSR1,FGFR1,STX17,CDC42,FTH1,ST7,ARHGAP1,SRC,IRF2BP1,PPAT,RHOJ,MSN,CTTN,BICD2,CCDC22,DNAJC5,RAB2A,PTPN11,FBXO25,CAPZA1,RAB3B,TGFBR2,SEPTIN7,IGF1R,PSME1,TFRC,EEF1A1,MTCH2,LMAN1,STX6,TMPO,CAV1,DNAJC1,ARF6,HSD17B11,RAC2,TES,AIFM1,PTPN1,UPK1A,DNAJC7,ESYT1,LAMP3,ELOC,DPP4,SLC25A46,PXMP2,STX7,STAU1,HSPA8,AKAP1,RAB5A,DNAJC3,SMARCD3,OTULINL,RND2,SEC62,DUSP22,AGTRAP,TAX1BP1,SEC61B,NTRK3,FIS1,SERPINH1,LAMTOR1,RHOB,NIBAN2,RAB11A,AP1M1,HNRNPDL,KRAS,RUVBL2,TMT1A,CCR1,STIM1,RPN1,RAB4A,DNAJC25,SOX2,GFPT1,HEXA,DIRAS3,HSP90AB1,RHOH,GJA1,NRSN1,RAB35,RHOG,AGR2,XPO1,ATG9A,LAMP2,PIK3R1,RAB5C |
| 5.067e-09 | -19.10 | UBE2J1 (ubiquitin conjugating enzyme E2 J1) | protein interactions | 51465 | 193 | 92 | 19454 | 5460 |
ERLEC1,RAB3B,TRIM63,FKBP8,RAB1A,RNF133,CLTRN,TMEM31,TRAPPC13,TOPORS,DDX39A,CLEC2B,CAND1,DNAJC1,DERL2,POLE3,LMAN1,LY6G6C,TMPO,PTPN1,HSD17B11,RAC2,TM4SF18,ESYT1,AQP2,SLC25A46,EDEM1,LAMP3,MFSD3,TMX2,SYVN1,DERL1,RAB9A,LMNA,SSR1,GHITM,FUT8,CDC42,ST7,SEC63,GXYLT1,RPS3,ELOVL4,B4GALT1,TRIM27,CHRAC1,MFSD14B,CREB3,KRAS,RNF26,CYP2C9,TMT1A,SLC39A7,STIM1,RPN1,RAB4A,TMEM14B,B3GNT2,DNAJC25,FAF2,HSP90AB1,TLCD4,OS9,RAB35,CD63,GJA1,RHOG,ATG9A,LAMP2,RAB5C,RNF5,PXMP2,STX7,JAGN1,BIRC2,RAB5A,CTBP1,OTULINL,SEC62,REEP4,B4GALT3,ARF1,S1PR4,DIO2,RRAS2,SEC61B,BRCA1,LMNB1,FCER1G,CYB561,ST3GAL1,TM4SF19 |
| 5.127e-09 | -19.09 | Antigen processing-Cross presentation | REACTOME pathways | R-HSA-1236975 | 101 | 60 | 10285 | 3229 |
ITGAV,RPS27A,PSMD4,PSMC3,PSMA1,PSMB9,CD14,SEM1,SEC22B,MYD88,SEC61G,IKBKB,ITGB5,TLR2,PSME2,PSMD6,PSMB4,PSMD1,PSMB2,TAPBP,PSMA6,CALR,TIRAP,FCGR1A,PDIA3,PSMD12,PSMC1,SEC61A1,UBA52,TLR4,VAMP8,UBB,MRC1,PSMD14,TLR1,PSMD7,VAMP3,CD36,PSMD10,PSME1,PSMA2,PSMB6,SEC61B,SEC61A2,PSMB3,PSMA4,PSMC5,PSMB11,PSMB10,PSMA5,LY96,B2M,PSMB5,PSMA3,TLR6,PSMC4,SNAP23,PSMD3,PSMB7,PSMB1 |
| 5.210e-09 | -19.07 | NXF1 (nuclear RNA export factor 1) | protein interactions | 10482 | 1336 | 468 | 19454 | 5460 |
DDX42,RP9,SURF4,DISC1,GNAI3,TP53,ESS2,H3C1,NUP107,RPIA,HNRNPK,MAP1B,DHX9,SHC1,USP2,PPIL4,TPM3,TMED9,CAND1,FZR1,R3HCC1,STX6,MRPS9,ITGA6,ALYREF,GATAD1,XXYLT1,SEPHS2,TFIP11,LUC7L3,AGO1,NME4,WDR55,PPP1R26,SMG5,TNFAIP1,SNX14,ENDOD1,BICD2,IGF2BP1,SUGP1,ATF4,SLC35B4,RPGRIP1L,DYRK1A,TBCCD1,SLC25A39,FAM210A,SEC61A1,PITPNB,CSNK2B,RNF187,MACROH2A1,LSM10,HGS,DHX38,ANAPC13,TMBIM1,NAB1,RUVBL1,SLC20A2,XPNPEP1,DCTPP1,SETD4,PEX3,CDC23,MAGOH,IFI16,DDX50,RAB5C,WWP2,XPO1,CTNNB1,ZNF740,OSBP,SUMO3,RNF144B,AASDHPPT,PEG10,HSP90AB1,CCT7,SIN3A,SSR2,RPRD1A,RBM5,NXT1,DUSP14,USP6NL,ZC3H14,SLC31A1,NDUFS2,TRA2B,SRSF2,ABCC5,DDX39B,PEBP1,HERC3,TAPBP,CCNI,DDX5,CCT2,CIRBP,S100A11,ATP5MC3,RCL1,MYC,HNRNPAB,HNRNPC,PSMD1,BAG3,TAGLN2,RPL10,ESR2,APEX1,GPN2,RETREG3,NDUFS3,HINFP,CMPK1,CD2BP2,EXOSC8,NOC4L,CDC42SE1,NKRF,ANKRD49,CLP1,GRSF1,ERCC3,SETD5,MRPL24,KRR1,PRR3,TCEAL8,DLGAP4,TES,CHMP1A,HNRNPH3,UBAP1,SH3GLB2,HAUS2,SF3A1,PIP5K1A,DDAH1,JMJD8,UQCRC1,NF2,FBXW7,PIK3R2,MIEN1,PIAS1,VPS28,INPPL1,RPA3,PAIP2,CDC73,HERC4,MAPRE1,PNP,CTTN,GNPDA1,NTN4,NME1,EXOSC3,CHMP4C,NDUFS6,DPH5,RAF1,RBM12,GABARAPL1,JUN,IFNGR1,GUK1,COPS4,AHCYL1,HSPD1,CIPC,HNRNPA2B1,OPA3,SRSF7,MRPL18,DROSHA,HNRNPD,VCPIP1,MED4,SLC20A1,RAB32,NDC80,BABAM1,HNRNPA1,ZNF207,DHX15,NUP35,KLHL7,PSMB5,SNX17,ELOVL1,SLC25A3,ANXA7,ACTL6A,NDE1,ASB8,RFXANK,NUDT3,SUPT4H1,SRM,YTHDF1,TMED3,FBXO30,NKAPD1,BIRC2,FYTTD1,PSKH1,YWHAZ,HSP90AA1,SCFD1,CCDC25,RPS5,ILK,ZNF250,NFYA,TMED4,PKP4,SMARCE1,B4GALT4,TAB1,GPR37,USP5,MAD2L2,POLR3B,PSMC3,UBL4A,IPO8,ACTR1A,HADH,URM1,WBP11,ZMYM3,ZMYM4,CDC40,KPNA2,TOMM40L,CAPZA1,DDR1,EIF1AD,PCYOX1L,BACE1,IDH1,TPGS2,LANCL2,BECN1,SNRNP70,NXT2,USP15,AGPAT1,CSNK2A1,COPS5,ANKRD10,IFRD2,NKAP,DKC1,FUNDC2,SURF6,CD274,GTF2B,EEF1B2,MCL1,VPS4B,RPA2,GALNT1,HEXIM1,PRKCA,HECTD1,ACACA,SPTBN1,ING5,CREBZF,UBE2K,KDM1A,RBM22,TOMM20,HSPA5,APMAP,RPF2,TNFAIP3,CEP85,MRPS21,ROCK1,SRPK2,RPS3,LIG3,SGTA,GLE1,PIR,CRKL,SUPT5H,TNPO2,OAZ2,KRAS,NUP42,VDAC1,POLDIP3,RUVBL2,NDUFB8,GSTM3,RIOX2,PPFIBP1,ADCK1,PCSK9,FAM98A,RTL6,MPDU1,SRSF1,EED,RFX5,SIGMAR1,NCOA5,PIH1D1,NUP62,RALYL,STAU1,MRPS7,PYM1,SLU7,HIRA,SNRPA,HSPA8,TIFA,RAP2A,COMMD9,TSEN54,RBM27,CHTOP,ELAVL4,GTPBP2,ZNF343,MLF2,PCCB,VCF1,KBTBD2,TRIM29,SNRNP40,MORC4,PPP5C,ATP6AP2,KRIT1,CREB3L4,APEH,MRPL49,MSRB3,EEF1A1,CAMK2G,APH1A,BACH1,CTNND1,MRPL22,PDE2A,PRDX4,SLC25A10,NSDHL,ZC3H11A,TTL,EPOP,ARL2BP,EXOC2,MPHOSPH10,EMC4,HDAC6,SLC25A17,POLE3,CAV1,DFFA,AIFM1,LMNA,SNAI2,EPHX1,CPSF4,CLSTN3,ATG16L1,PSMC4,RBFOX2,SAP30BP,CCND1,RBMS2,DESI1,LDOC1,AATF,POLDIP2,DNAAF9,SLC39A9,SIRT7,OPHN1,SQSTM1,DEDD,CASC3,CDC16,ATP5F1A,USP14,SLC25A4,STUB1,INPP5K,EIF4A3,UBE2I,GPBP1L1,RWDD3,GTPBP1,CYB5B,TPD52,FEN1,E2F4,KHDC4,ACO1,NUP153,GTF2E2,WDR37,LASP1,EMC8,G3BP1,SRSF4,UNC119B,MORC2,ATP6V0B,SRSF8,VPS26B,ADAT1,TMEM164,NQO1,RPL23,UBXN6,PSMD3,PRPF19,TRA2A,OCRL,KIF3B,SNX1,THOC2,PHB1,TSG101,XPO5,HP1BP3,APOBEC3C,AGGF1,LNX2,IDH3B,LMO4,MCMBP,COIL,THOC3,UPF3B,NUP50,RNF10,TAFAZZIN,TBC1D16,MYO6,SP1,RIT1,DSN1,CUL3,CUL2,PDE4B,RNF40,MCM4,RBM15B,UMPS,CHP1,TNPO3,CPSF1,CYB5R3,RAN |
| 5.283e-09 | -19.06 | MRPS35 (mitochondrial ribosomal protein S35) | protein interactions | 60488 | 298 | 130 | 19454 | 5460 |
SRP14,MRPS9,SSBP1,ALYREF,COX4I1,RAP1B,PRR3,TRMT10B,FZR1,CAND1,MRPL50,CGAS,VPS26C,PRNP,RBM42,SURF6,MRPS23,GRSF1,ATP1B1,E4F1,SNRNP70,CHCHD1,TMEM70,NOL12,DNAJC4,RPL23A,CLPB,MRPS18B,RPL3,H3C1,FASTKD5,MEPCE,MRPS18C,RPL17,MRPL11,APOBEC3D,H2AX,AURKAIP1,DUSP1,METTL15,MRPL36,GFM2,MRPS28,VIRMA,RPL26,TUFM,RC3H2,ZBTB38,EPHA2,DNAJC19,UBE2H,BAP1,RPA3,GFM1,RPL4,HMGB1,SLC25A51,CRYZ,ABCC2,KLF12,RBMS2,RPA2,MRPS34,ZNF574,HEXIM1,KLF4,MTRES1,HAUS2,SRSF1,FBXO32,GATD3,RPLP1,HNRNPL,RMND1,MTRF1,RPL6,HNRNPA1,TRA2A,DDRGK1,RHOG,MRPL18,MRPS26,POU5F1,ARMC8,HSPD1,PPAN,HINT2,MRPS11,COX8A,SRSF7,MRPS17,SRSF4,IMMP2L,HNRNPDL,ZNF263,E2F4,SOX2,TULP3,PDHA1,RPL18,TACO1,MTG1,CCDC90B,RPS9,LAMTOR3,RPL35,RPL19,PARL,PRRC2A,RPL10,AUH,MTG2,MYC,CFAP20,PMPCA,CUL3,PSKH1,MRPS25,HTRA2,MCAT,RIT1,NGRN,EXD2,HSCB,NOP53,MRPS7,ATP6V1C1,DUSP14,RPL27A,TIMM29 |
| 5.393e-09 | -19.04 | MSI2 (musashi RNA binding protein 2) | protein interactions | 124540 | 164 | 81 | 19454 | 5460 |
MIRLET7I,HNRNPH2,MIR34C,RNF113A,BAP1,MIR10B,RPA3,PHYHIP,MIR205,MIR106A,MIR7-3,RBFOX2,MIR34B,MIR21,FKBP1A,MIR7-1,CDK1,RPA2,MIRLET7B,MIR16-1,MIRLET7D,UBE2L3,SRC,SRPK2,CTSB,YES1,MIR98,CUL3,MIR363,IGF2BP1,EIF3G,SPOP,RC3H2,MIR145,MIR9-3,MIR200A,MIR9-2,PABPC1,MIRLET7C,MEPCE,EIF3E,MIR16-2,CA10,G3BP1,GJB1,UFM1,MIR155,MIR15A,H2AX,MIR200C,SOX2,MIR222,RAF1,TP53,MIR20A,MIR17,MIR214,MIR141,MIR25,MIR106B,MIR7-2,PHB1,MDM2,CHMP2A,HNRNPL,FZR1,MIRLET7G,PRNP,MIR9-1,HNRNPA1,MIR29C,CPEB1,CRIP1,GRSF1,MIR143,MIR221,MIR1-1,MIR34A,ARMC8,MRPL18,SNRNP70 |
| 5.421e-09 | -19.03 | NDN (necdin, MAGE family member) | protein interactions | 4692 | 387 | 161 | 19454 | 5460 |
TOP1,AKR1B1,EEF1B2,SYNCRIP,HACD3,SSX2IP,RPS2,RPL24,ECD,EID1,GAPDH,RPL17,PTGES3,OLA1,RPS13,TMEM33,HNRNPK,SRPRB,DHX9,PC,RPL3,ZC3H11A,RPL23A,IK,NEFL,RPL15,DDX39A,EEF1A1,ACTR1A,RPSA,TP53,CCT5,MYG1,RPL13A,NDN,LDHA,BUB3,ALB,SEC61A1,PSMC5,ENO1,EIF4A3,CTTN,TUBA1B,RPS3,SERTAD3,IGF2BP1,PAIP2,TUFM,NONO,ATP5F1A,RPL7A,HSPA5,EID2B,RPL4,CERS2,H2BC12,PGK1,DDX46,RPL27,ACACA,RPLP0,HNRNPH3,LEPR,CDR2,TFIP11,HSP90B1,ZCCHC17,CDK1,EID2,LPXN,UBA52,RPS14,HSP90AB1,DHX15,CCT7,SRSF10,PPIA,CACYBP,TCP1,RPL7,PAIP1,HNRNPL,PPP2CB,SRSF1,RPL8,RPL9,RPL23,DDX1,HNRNPD,FKBP4,EIF3D,HNRNPA1,RPL6,PRDX1,HNRNPDL,RPS4X,SRSF4,RPL28,RUVBL1,VDAC1,HNRNPF,G3BP1,RPS24,SRSF7,RUVBL2,CCT8,PABPC1,HNRNPA2B1,HSPD1,SLC25A5,RPS23,CSTPP1,RPL18,RPS11,CFAP36,GDI2,TUBB4B,EEF2,RPS7,E2F4,SUPT5H,RPL19,RPL10,GNB1,TUBB,RBBP4,ACTB,MATR3,PRDX2,ATP5F1B,RPS9,RPL37A,SNRPD1,CYB5R3,RAN,VDAC2,FAU,RPS26,HSP90AA1,FTSJ3,CKB,CCT2,MCM3,LDHB,MYC,EEF1G,PHB2,IL1A,FXR2,HNRNPA0,TRA2B,DDX5,HSPA8,XRCC5,NUFIP2,PALS2,ETF1,GKAP1,PPP1CB,RPL27A |
| 5.478e-09 | -19.02 | MED21 (mediator complex subunit 21) | protein interactions | 9412 | 151 | 76 | 19454 | 5460 |
MED27,MED21,MED29,MED4,GTF2E1,VTI1B,POLR2I,CDK9,HRAS,RPRD1A,GTF2B,POLR2L,CDK8,PTRH2,POLR2G,SMARCB1,POLR2C,DHRS3,POLR2D,GNAQ,BIRC5,HGS,GNAZ,MIEF1,VDR,MED9,TP53,RPAP2,DDX39A,HPCAL1,KRAS,VAMP8,PDRG1,RNF20,TFG,STX8,CCNY,MED10,BRCA1,ZMPSTE24,CREBBP,MED22,PTPN11,BTF3,RNF40,RACGAP1,AR,MED17,YES1,POLR2B,ESR2,SRC,EFNA5,VAMP3,TRIM27,POLR2F,GTF2F1,ZNF655,VAV2,MED23,APOC2,MED31,CSNK1G3,GTF2H4,ATG16L1,FBXL19,MED30,ZSCAN1,CDKN1A,CDK7,BORCS6,CNTN1,MED11,FBXW7,SKP1,MED13L |
| 5.623e-09 | -19.00 | PYM1 (PYM homolog 1, exon junction complex associated factor) | protein interactions | 84305 | 128 | 67 | 19454 | 5460 |
SOX2,ISG15,GTF2E2,MSX2,RPS7,TOP3B,RAF1,ATP5PB,E2F4,RPS23,EZH2,MAD2L1BP,DNAJC2,RPS24,UBE3A,EMC2,CDKN2C,RPS4X,RPS13,TRIM26,SLC25A32,VRK1,THRAP3,DNTTIP1,XPO1,MOV10,RPS2,MAGOH,ANKRD49,DCAF5,SNRNP70,TNKS,ALYREF,RPL35A,RPS16,FZR1,RPS10,PRNP,RPS27L,MND1,RPS14,EP300,AKAP1,DDX39B,BAP1,UPF3B,RPS28,PNO1,STAU1,RPS29,DNAJC8,MYC,RPS26,RPS5,CASC3,UBE2H,RC3H2,RPS9,RPS20,RPS12,FAU,RPS3,EIF4A3,MAD2L1,CLIC4,DEK,MAGOHB |
| 5.626e-09 | -19.00 | CBL (Cbl proto-oncogene) | protein interactions | 867 | 499 | 199 | 19454 | 5460 |
RAB5C,UBE2E2,CTNNB1,TBC1D5,PPIB,YWHAH,YWHAG,XPO1,NCK1,CRTAP,HSPB1,YWHAB,ARMC8,CBL,POLR2L,PSME2,TRAPPC10,CORO1C,EED,HTR2A,TRAF2,TUBA1A,PDHA1,IRF8,TUBB4B,PLS3,CRKL,SERPINA5,CCT8,TRIM11,RUVBL2,TRIM21,CHCHD2,SFN,EPS8,SERPINH1,CDKL2,CRMP1,SLA2,PCMTD1,SYK,ATP6V1C1,LMO3,FRS3,PLAA,NUFIP2,XRCC5,TMEM160,CD40,EP300,DDX5,HSPA8,PHB2,UBE2D3,ITGAV,MTMR12,GAPDH,CD81,FCGR2A,SHC1,TRAPPC2L,ATP6V1D,CD247,UBE2N,UBE2G2,ITGA6,EEF1B2,ITK,LCP2,EPHB6,RAB39B,TMPO,MYL12A,TP53,CD38,FAM162A,CAPZA2,TFRC,PIK3CA,SPRY1,GRAP2,PSME1,TGFBR2,CAPZA1,PTPN11,MGST2,PRKACB,UBE2E3,PSMC5,STAT5A,SRC,UBE2W,CAPN1,SPTBN1,CFTR,CD2AP,CDC42,WWP1,PTPN22,RPA2,ACACA,GSTP1,PRKCA,UBE2M,IRF3,ARHGEF6,BANF1,DLAT,HSPA5,BNIP3L,TRIM8,STOML2,PIK3R1,LAT2,TRAF6,UBE2D1,HNRNPD,PHB1,CBFB,ATP6V1A,TSG101,SPTAN1,SNX18,PRKCQ,EGLN3,TXNRD1,B3GNT2,TULP3,EZH2,PGGT1B,ZYX,MAP3K11,BAG2,JAK1,SLC39A7,SLC39A3,KIT,FLOT1,RPS27A,PIK3R3,CUL3,RPS29,IRF1,YWHAZ,ARF1,GNG12,TUBB,ACTB,JAK2,ERH,VAV2,MYL6,ANXA7,ATP6V1G1,PSMC1,IRF4,H2AC14,LRRC40,FGR,SMAD3,HRAS,PRNP,MDM2,H2AJ,EEF1A1,TRAPPC13,SNAP23,IGF1R,HSPE1,CDK2AP2,CNOT7,PRDX4,RIGI,CSK,MAPRE1,EPHA2,ENO1,CTTN,CCNF,PTEN,UBASH3B,YES1,TMOD3,VIRMA,GNAI2,UBE2L3,UBA52,MYL12B,STOM,PICALM,LMNA,MET,MYH2,INPPL1,SQSTM1,PIK3R2,GTF2I,EIF5B,PDHB |
| 5.629e-09 | -19.00 | SLC25A5 (solute carrier family 25 member 5) | protein interactions | 292 | 364 | 153 | 19454 | 5460 |
RPL9,FOLR1,PHB1,EED,RPL7,EGLN3,ELK1,IFI16,WWP2,RPL6,DDRGK1,MAP3K14,CTNNB1,AGR2,MAGOH,RPL23,HSPB1,OSTM1,RPL31,COX8A,RPS24,TNF,TRIM37,VDAC1,RPS4X,B3GNT2,RAF1,TUBA1A,NCSTN,SOX2,LGR4,RPN1,EZH2,PDHA1,MTA2,RPL18,RNF126,RPS23,VDAC2,DLST,NFKBIA,DKK3,AP2M1,RPL37A,SEC61B,LGALS3,CBX5,APEX1,RPL19,MYC,CUL2,CUL3,BTF3,BAG3,NTRK3,HSP90AA1,DDX39B,ATP5MK,RPS28,NMRAL1,CRY1,HSPA8,NPTN,EMC1,UFL1,ADRB2,STAU1,COIL,ASB3,PPT1,TBC1D17,PIH1D1,AIFM1,RCHY1,DCUN1D1,CAND1,MBD5,CDK9,PMM2,COPS5,HDAC6,TMEM70,RPS2,USP15,RPL10A,MAP1B,FAF1,DDR1,SNIP1,RPL23A,IGF1R,HUWE1,CD80,PSMB10,MEPCE,FBP1,UBL4A,TP53,RPSA,TRIM6,MAP2K3,RPL15,CBX3,TFCP2,SLC25A20,FURIN,SLC25A24,RPS3,CCNF,EIF4A3,GSK3A,TRIM24,PTEN,NDN,SLC25A4,PRKCE,SMURF1,VIRMA,CSK,RALB,RPL7A,FBXO7,AR,MRPS16,SPOP,RC3H2,ATP1A1,SMAD2,UBE2H,INPPL1,RPA3,PML,RTN4,RNF113A,NF2,FBXW7,RPL4,PIAS1,TOMM20,HSPA5,AATF,CCND1,GABRA1,CDK7,CFTR,LMNA,CDK1,MRPS34,RPA2,METTL14,UBE2M,HEXIM1,HECTD1 |
| 5.673e-09 | -18.99 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 3485 | 1167 | 18204 | 5365 |
ZNF24,ZBTB16,PPP2R5A,MCL1,PLCB1,IFNK,ATG7,TLR9,SMARCD3,TNFRSF1B,MLLT6,ADM2,HDAC3,MIR96,DNAJB2,IFNA2,UBE2S,TNIK,MEF2B,ZNF507,CDC73,DNAJC3,PPP1R10,EHD4,LCP2,CLEC6A,MIR204,MIR423,WNT10B,NMI,SMYD3,MAD2L2,SSBP3,PAX6,RIGI,MED27,TP53INP2,GTF2A1,PRKAG1,GABPB1,UCN,CD80,BABAM1,UHMK1,FOXP3,CD274,AKT2,PPP1R12A,ACTL6A,SLX1A,SMARCE1,TENT4A,HAX1,PRNP,BVES,MIR130B,SF3B4,CLIP3,E2F4,UBE2K,ELF1,MMP14,FCER1G,DDX1,MAGEC2,ZNF513,MIR223,ACVR1C,MMP9,CD86,IFNA10,PAIP1,PADI2,SOX21,TP53INP1,BAX,TRAF3IP2,IL6,EFCAB7,MOB3B,AGPAT1,ID4,TOM1L1,FAS,KIT,ANP32B,PID1,XBP1,MIR320A,TOLLIP,MET,SOD1,AR,UBE2D1,HNRNPAB,CCND1,CYTL1,PAK2,MIR130A,IL2,MIRLET7B,TGFBR2,NR1H2,FGF1,MIR125A,NRP1,PCSK9,E4F1,TAF11,RGMA,ATF1,CDK5RAP3,EGLN2,AIFM1,AKT1,DYRK1B,IL1B,TGFB3,CEBPE,MIR182,ELAVL4,VSTM2A,WNT7A,PPP3CA,FAM107A,RPL26,CCT7,SERTAD2,MIR211,ITGA2,SLCO3A1,RPS4X,IFNA13,EXOSC8,FUBP3,TLR6,AGR2,MIR675,GRSF1,TCF23,NSG1,CALR,SIRT7,IGF1,HMX2,NFKBIA,APH1A,DKC1,ENY2,CNOT2,CREB3L4,MT3,TEF,NEUROD6,TOX,CCND3,TNFAIP3,GH1,RBBP4,TXN,BAK1,VDR,MAX,OSM,CCL1,NR2E1,PIK3R1,KLF1,SETD4,CUL3,PIK3R2,TRUB1,CAMK1,TCP1,SOX14,DEK,ELK4,NIBAN2,FZD4,MTPN,PRELID1,EIF3E,FGF23,BCL9,TLR1,NSMCE3,MIR137,MIR769,IL15,CCAR1,IL23A,MTA2,SLC38A2,VEGFA,ASB11,ELK3,WRAP53,UQCC2,IL18,RB1CC1,CSH1,TFEB,MIR140,PDE4B,HNRNPA2B1,PIK3CG,RNF41,CD40LG,FASLG,CD58,TCIM,APEX1,NTF4,IL17F,TAF10,CAMP,ETV6,MIR15A,CACUL1,ROCK1,SUPT4H1,TLR2,RARRES2,MYLIP,MIR183,MIR373,ZNF287,CYP1B1,MRPL12,APOBEC3A,TBK1,CYRIB,XRCC5,VIP,STAT5A,AKAP8L,VAMP3,RNF10,PIAS1,DIRAS1,FAM161A,MAPKAPK5,ARL2BP,NUP62,POU1F1,PDE2A,WBP2,MAP2K6,IGF2BP1,PHF23,SEMG2,PSMC5,CHCHD2,CLEC9A,CCL2,DCUN1D3,SERTAD3,MIR16-1,PIH1D1,MED10,ACVR1B,CD40,BOLL,HILPDA,PSMC1,SYK,FGF16,PITHD1,NLRP1,NR1I3,CREB3,STK11,APOBEC3C,ALKBH4,TRIM5,MED22,PRDX6,FOXA3,FBXW7,NME2,PRR5L,EAF2,NOG,TESC,S100A8,SGF29,HDAC6,MIR101-1,TCEA1,NIF3L1,CD2,DCUN1D5,SPTBN1,VSIR,MED23,PRKAB1,LAMP3,SERTAD1,YES1,BIRC2,CNOT6L,PSMC4,EGLN3,LACRT,TRIM32,TRMT112,TNRC6C,UBE2L3,MED9,MYD88,IL4,NPTN,ILF2,TAF5L,MDC1,HTRA2,IL20RB,SOCS5,HSPA5,NLRP9,MIR146A,DGCR8,CD81,NKRF,CD46,MIR149,FAM98A,ZBTB17,MAVS,FURIN,KANSL3,GPBP1L1,TYROBP,EFNA5,ING2,USP5,RUVBL2,TADA1,MIR132,BCL10,IL12A,RWDD3,EIF5A2,LILRB1,TPD52L1,YWHAH,MIF,CCL3,HNF1B,SETD7,KLF12,CSF2,RFX4,IL6ST,GTF2F2,HEY2,BARX2,MAP3K12,IRF3,TLR3,EPHA4,DEFB124,MOSPD1,AKAP12,DYRK2,PELP1,EFNA3,RORB,CCL5,FZR1,PPIA,CDC42,NUPR1,AGO1,LRRTM3,DUSP19,RCHY1,FERMT2,CSNK1E,RTRAF,IGF1R,SFRP1,STAT2,SOX9,NDFIP1,HOXC4,PAEP,RGN,SUB1,CSNK2A1,HNRNPA0,DNAJB9,SF3B5,CNOT6,DLG3,RBM23,TOPORS,FIS1,CDC5L,KDM1A,NR1I2,PRPF19,RGMB,EDF1,IL5,TLR7,ZBED1,BUD23,NUCKS1,FCGR1A,ANKRD49,STPG4,MIR511,MAP2K1,HDAC5,HGS,PRMT2,IRF8,RAB1B,DKK1,DHX9,HOXB1,SPP1,RFC2,MSL2,PRDM4,HAND2,MBD3,HCFC2,ZNF345,ADRB2,UAP1,RNF8,ISG15,STAT6,CCR7,MAP2K3,ZFAND2A,MIR192,LRP3,OSBP,PARM1,TLE1,RPRD1B,TRIM8,MIR9-1,SCAND1,LTB,RERE,RAB29,RHOG,FOXJ3,PLGRKT,TRA2A,CDKN1B,TRIM52,PSME2,SGTA,EPCAM,MIR212,RBM3,RBCK1,TRIM15,TRIM44,DET1,RNF139,ZNF668,LUM,KPNA2,C1QTNF1,HMCES,LHX2,PRIM2,DROSHA,GTF2I,HEXB,MIR195,FAF1,B2M,PTPN1,BAG2,GHR,CSRNP3,RAP2C,HSPA8,CNOT8,MGMT,ZNF473,TRIP4,ZNF574,MIR26B,ARF4,JADE1,TLR4,APLNR,DLG4,KLF4,ZBED3,PAX9,STK4,TP53,ACTL6B,MDM2,TNFSF10,LEPR,NEK7,NCBP2,OAZ1,SOST,MIR1-1,NLRP3,CNTN1,CEBPG,GJA1,ZBED4,MIR17,MIR214,NEUROG2,CTSD,CLDN3,AIF1,FOXC2,IRF4,CDK9,NDN,CDKN1A,NFYA,SUPT5H,TENT5C,MED4,TNFAIP1,CITED1,RB1,NLRP2,ILK,SH3BGRL,PLAC8,HFE,CLDN4,TOP2B,FGF7,STUB1,LURAP1,CCT8,GTF2A2,IL1RAP,MZB1,EMILIN1,MED11,MIR98,ITGB8,HINFP,OAZ2,CX3CL1,NGRN,XCL1,MUL1,SF3B1,RBPJ,FGF3,HMGA1,ACTB,TNF,PDE12,RUVBL1,PHB1,ING1,FCGR2A,MIR191,MYBL2,SYNCRIP,RGCC,UBE2B,CREBL2,MOB3C,NOS1AP,DNM2,EMP2,MIR548C,SMURF1,MIR30B,MIR21,MIR519D,ECD,RPS2,LILRA2,BCL2A1,ELK1,LYAR,MED29,MIR33B,RMND1,FOXD3,IREB2,DXO,POU5F1,TCF21,MIR210,POLR3F,PMAIP1,RBBP9,CD36,HSPD1,ENO1,AURKAIP1,LDLR,MIR885,DMAP1,OTX2,JUNB,PRL,PNP,JUN,HAS3,PELI1,PPARA,FLOT1,IFNGR1,RXRG,TRAF7,VEGFC,CXXC1,MTA3,NEUROD2,ZNF263,MIR185,POLR3B,RNASEL,LDB2,FGR,UBE3A,RNF14,IL12B,THRAP3,FOXP1,STOML2,ZNF267,ZFP64,UBB,ERP29,GTF2F1,RFX5,RSAD2,EIF2AK2,CD14,MIR206,MLLT11,RLN2,AATF,TNFSF13,CREBZF,RIOK2,GRIA1,ODAM,LMO4,DIRAS2,UBE2N,CARTPT,TRIM24,RRN3,MIR497,MSN,CRKL,CDK12,ARRDC3,SS18,MIR221,ATP5IF1,PSMC3,SKP1,CAND1,PKIB,STAT1,LRP6,TIRAP,BCL2L1,MED31,MORF4L1,JAK2,PTEN,LMO2,BAD,DERL1,SMCHD1,CD34,RAB27A,RAMP3,DVL2,LACC1,KPNA6,CRY1,GSK3A,NOP53,TNFSF15,LMNA,UBE2V1,CDC7,UBE2V2,KHDC1,TANK,INO80E,SMAD4,GABARAP,PRMT5,RNF128,EIF3D,PIK3R3,NAA16,WDR77,BOK,PACSIN3,KARS1,SNX5,EP300,PDCD10,RFC3,KLK5,TMEM106A,CYFIP2,CTNNB1,SHLD1,HYAL2,BACH1,CTSK,PQBP1,BRMS1,IRF1,UTP15,AFAP1L2,MIR625,MIR100,RFXANK,NBN,EIF2B5,ACTR2,METTL14,NTRK3,ZNF319,IFI16,TLR8,NTRK2,LMO3,CCT5,BMPR1A,MIR181C,SMARCB1,MECP2,MPV17L2,SMAD9,SOX3,NFE2L2,TICAM1,MIR29A,EXOSC3,BMPR2,TFE3,SEMA7A,SRC,SUMO2,SMARCA5,ZNF609,ANGPT1,PTGES3,TNFSF12,NRDE2,FAM162A,TRIM21,CD200,ATF4,POLR2G,SQSTM1,LEP,HNRNPK,ZNF175,PHB2,MED17,TAB2,IFNG,MIR34B,DTL,STX5,MIR135B,STK16,OAZ3,MEF2A,FXR2,TRAF6,NDP,TICAM2,NEK2,CD38,MIR181D,TRIB1,PLAGL1,RNF40,TLR5,CCL19,FAM168A,PML,BMPR1B,IRF2BPL,TFCP2,HCLS1,FOS,DISC1,CHI3L1,PLP1,SUPT3H,PABPC1,HLF,TESK1,WBP1L,NFKB1,MIR491,TERT,CRADD,RALB,KLF10,MED30,MIR205,CLU,STAP1,NKX3-1,ATF3,FCGR2B,RPS7,PKNOX1,MIR24-1,CRTC2,SMAD3,CSRNP1,PCBD1,TRIM62,TFRC,SELENOK,HNRNPD,WNT2,RHBDD3,TUSC2,TAF9,KMT5B,RAP1A,EIF4A3,TAF2,MIR342,IFT57,SMAD2,ALKBH5,SLC38A3,BRCA1,BUD31,RBM22,IFIH1,RUNX1,ZMPSTE24,IRF9,CD4,HBEGF,EGR2,ARL6IP5,TNKS2,PSEN1,RPS27L,APOBEC3F,ZGLP1,SNRNP70,MIR324,IDE,TNKS,TAB1,USP8,RC3H2,MEAF6,MEPCE,CAV1,IFNB1,MEF2C,SUPT7L,MSTN,CAV3,VGLL4,PIM2,AGAP2,HSP90AB1,CBFB,CD28,RAB1A,DDT,HTR2A,INPP5K,APLN,SSBP1,ATP6AP2,MOV10,CDK1,OSR2,RPS6KA4,PDCD5,SASH3,PSRC1,CD83,MIR190B,TNFSF8,SMAD5,SOCS4,MED21,HSP90AA1,NFIL3,DLX1,WWP2,SSBP2,HNRNPA1,CASK,MIR106B,SPON1,G3BP1,GPSM3,DAPK1,CDC20,HSPB1,MARS1,MIR142,MYC,ZER1,IER3,FRMD8,CREB1,MTF1,AIP,BAZ1B,TRIM22,CCL21,MIR20A,TADA3,NFE2,CIRBP,PYM1,CDK7,PICALM,MAFG,LITAF,HSPE1,ACTN4,MACROH2A1,RIT2,MIR708,CCT2,MIR200C,SMAD1,IRF7,MMD,COPS5,SUMO1,RNF126,HNRNPC,OAS1,SETD3,TRAF3IP3,FOSL2,LTA,PAGR1,CTBP1,PRKCB,SHC1,ABHD14B,PXYLP1,DYRK1A,GCLC,TRIM37,RAP2B,IRF2,USP13,SOX2,PTPN22,WASL,NFKBIB,MTDH,ADTRP,PROX1,CREBBP,TNFSF18,GREM1,ZBTB18,SNX33,KLK3,CDH13,PIWIL2,CHP1,TGFB2,IL1A,MIR144,KRAS,NOTCH2,SVIP,SRPK2,RASL11A,ACTA2,DPY30,TF,ZBTB38,IRF6,IL2RG,NCK1,FGF10,PCNA,SEC22B,GPNMB,JUP,PRKCQ,RNF187,MIR106A,PGR,FAXDC2,ZNHIT1,RAP2A,RNF20,HECTD1,BTG2,COP1,MIR193A,DCP2,CCNA2,CSNK1A1,PTGER4,CCDC22,SFRP4,RPL23,SP1,PPARG,GAPDH,EGR1,TGFB1I1,IKBKB,MYRF,IL34,CNOT7,NR4A2,RAD21,SLC6A4,EPO,ITK,IL7,RFXAP,EZH1,CHRNA7,EZH2,IER2,IL3,UPF3B,YTHDF2,ESR2,NCSTN,NFYB,FBXO22,FGF22,SIX5,ADORA1,ACSS2,VGLL2,SCAMP5,MIR340,P2RY1,SRSF1,FGFR1,PSENEN,HELT,DNAJC2,CDK6,TFPT,EYA3,TRIM27,DDIT3,TOMM70,HUWE1,PTPN11,IDO1,TENT5D,SPPL3,CTSC,CCNY,CXCL8,TAF7,DIPK2A,UBP1,MIR34A,IL13,ITGA6,MITF,VPS72,CLEC7A,IL21,ACVR1,LDB1,PSME1,BRD3,TFDP2,MIR657,PLSCR1,BCL7C,POMT2,MIRLET7C,F2,CCR2,SPHK2,RFC4,USP16,PSMD10,TNFRSF14,CXCL10,DCUN1D1,ZNF593,CGAS,MIR424,DAP,ADNP,STRADB,OGG1,H2AX,FBXW11,TRA2B,INO80C,ZNF770,VPS28,SSBP4,MIR495,HMGB1,BCL7B,YTHDF1,AGER,ZNF304,HRAS,PYCARD,MIR23A,BATF,LARP4B,S100A10,CAB39,GTPBP1,GABPA,ARMCX3,RAF1,H2AZ1,YAF2,ROCK2,IL10,MIR640,STN1,PTGFR,MAP3K11,DDRGK1,CRLF3,ADIPOQ,POLDIP3,NAA15,LBH,FGF17,RBBP7,RPS3,EEF2,LY96,TRIM6,NMBR,RFC5,MSX1,CX3CR1,MIR145,TRAF2 |
| 5.688e-09 | -18.98 | NOS2 (nitric oxide synthase 2) | protein interactions | 4843 | 180 | 87 | 19454 | 5460 |
CLIC4,PSMD4,PSMD6,ACTB,SNRPB,PSMA4,HSP90AA1,ICAM1,CCT2,YWHAZ,PSMD14,PSMA3,XRCC5,PSMC1,SKP1,CDKN1A,SLC25A3,PSMB7,MMP14,GATD3,KRT8,HSP90AB1,CCT7,RPL7,TCP1,SNRPD3,HNRNPA1,YWHAG,QPCTL,PSMD3,HSPB1,DICER1,RPL23,PPM1B,AGR2,HINT2,RUVBL2,PIK3CG,TRIM21,BAG2,RPL31,HSPD1,SLC25A5,CCT8,RPS4X,PSMD12,HNRNPF,PSMA2,PSMA1,PPP2R1A,ACTN4,PSMC5,CDIPT,STUB1,RPS3,ENO1,PSMA6,SRC,TXNDC12,RPS17,CALU,SOD1,HSPA5,NDUFAB1,PSMC4,RAC2,AIFM1,SSBP1,HACD3,CAV1,ELOC,DNAJC7,NME2,PSMD7,RING1,HINT1,SPSB1,SMN1,MPST,PTGES3,CAMK2G,PSMA5,HUWE1,HADH,CCT5,PSMC3,NHERF1 |
| 5.754e-09 | -18.97 | negative regulation of molecular function | biological process | GO:0044092 | 744 | 291 | 18204 | 5365 |
GSTO1,SUFU,MIR711,BRMS1,NR0B1,CDKN1B,RPL23,TCEAL7,PAQR3,MIR153-1,SFRP4,CAMK1,CTNNBIP1,CCDC22,TFIP11,PPARG,MIR212,MIR218-1,UFL1,IFI16,GAPDH,CYP27B1,IKBKB,RBCK1,EPO,SERPINA3,LGALS3,UBASH3B,TIMP1,CEP85,B2M,VEGFA,FZD6,FAF1,SERPINH1,PTPN1,ADORA3,BAG2,SRC,SH3BP4,TIMP4,PTPRQ,ITGAV,SERPINI1,COMMD6,IFI6,DDIT3,TRIM27,CD200,TRIM21,MIR140,THY1,MIR590,HEXIM1,KLF4,PHB2,TP53,IFNG,TNNT2,SUMO3,GNAI3,TAF7,MIR873,MIR34B,NOSIP,MIR133B,MIR15A,MIR34A,MIR1-1,ROCK1,PDCD4,SERPINB11,CEBPG,CYP1B1,CAMK2N2,GADD45A,UBLCP1,NLRP3,GSKIP,CLEC12B,PLN,MIR17,PPIF,MIR378A,TRIB1,CCR2,GRM2,MDFI,CDKN1A,ZNF593,DISC1,PSMD10,RB1,SRI,DAP,MIR16-1,NFKB1,PIH1D1,TESK1,OTULIN,HEXIM2,TMBIM6,RGS2,ARFGEF1,RALB,HFE,DFFA,CORO1C,MIR495,CCAR2,DUSP10,STK38,PKIA,HRAS,PYCARD,NOG,MIR208B,RPS7,CAB39,HECW1,HDAC6,NFKBIL1,DUSP22,ROCK2,IL10,XCL1,MIR101-1,MIR24-1,RAF1,ADIPOQ,TNF,IFIT2,CAMK2N1,ACTB,DUSP1,PPP1R1B,TMIGD3,LAMP3,SERPINB1,CRHBP,SERPINB10,SERPINB6,MIR148A,PPP2R5A,SLPI,CYP2D6,SOCS5,GFI1,TLR9,PKIG,MIR208A,PSEN1,LILRB4,MIR21,DNAJB2,SFN,DNAJB6,CPNE1,VCPKMT,FOXS1,SERPINB9,TNKS,KCNAB1,CLIC2,CAV1,MAD2L2,CAV3,MIR33B,GPR35,MIR129-1,ANXA4,CNRIP1,HP,TAX1BP1,CDKN2D,MIR210,FKBP1B,ERRFI1,RWDD3,INPP5K,FOXP3,JUN,MIR186,ID1,PPP2CB,PPP1R12A,SERPINA5,PPARA,RNF34,TMBIM1,HEY2,OXSR1,SPRY1,SOCS4,MIR130B,PRNP,LRRC14,WWP2,YWHAG,G3BP2,CST3,HSPB1,NUPR1,PRDX3,DUSP19,PYDC2,PPIA,MMP9,GNAQ,RTRAF,GTF2F1,SERPINA1,TIMP3,BAX,CSNK1E,NDFIP1,CBL,GNAI2,MIR20A,MET,EIF4A2,CSNK2A1,ADRB3,IGBP1,BANF1,ATP1A2,SLC8A1,CSTB,ATP5IF1,PAK2,MIRLET7B,CAAP1,CSTA,KDM1A,PCSK9,LRP6,MACROH2A1,CAND1,MIR339,PKIB,FKBP1A,CTTNBP2NL,MIR29C,JAK2,PTEN,MAD2L1,TSG101,ATP2B4,MIR200C,CRHR1,ABCE1,MIR448,DEFB114,NUCKS1,SUMO1,PRKCE,PRMT2,GSK3A,RAMP3,CDK5RAP3,SIAH2,IL1B,GSTM2,AKT1,SERPIND1,SPOCK1,DKK1,PTPN22,MIR30D,TRIM37,ADRB2,DRD3,BHLHE40,PROX1,MIR92B,MIR152,MIR192,MIR144,DUSP3,CHP1,SPRED1,NFKBIA,DPEP1,DBNDD1,GPX1,MIR9-1,MT3,TCAF2,HYAL2,GSTP1,TNFAIP3 |
| 5.771e-09 | -18.97 | DDI2 (DNA damage inducible 1 homolog 2) | protein interactions | 84301 | 118 | 63 | 19454 | 5460 |
PSMD14,CCT2,HSP90AA1,PSMA4,NIBAN2,PSMB2,BAG3,USP14,PSMD1,H2BC9,PSMD6,ADRM1,TXN,PSMD4,VIRMA,PSMB6,PSMA6,TRMT6,CCNF,PSMC5,METTL14,PSMB7,PSMB3,PSMC4,DDI1,PSMC1,PSMA3,TXNL1,PSMD7,PSMD10,VPS26A,PSMD3,SUV39H1,HYPK,CCT7,HSP90AB1,PSMB5,PSMB4,PSMB1,HP1BP3,PSMC3,RAD23B,C1QC,RANBP1,CCT5,TP53,NAA15,UBL4A,EEF2,EEF1A1,TTC4,TOM1,PSMA1,PSMA5,SEM1,PSMA2,PSMD12,CCT8,HSPD1,SLC25A23,UBE3A,CPNE2,RUVBL2 |
| 5.776e-09 | -18.97 | GTP binding | molecular function | GO:0005525 | 374 | 164 | 18094 | 5411 |
EHD4,MRAS,RAB31,GUCY1B1,RAB9A,RAB3B,DIRAS3,IRGQ,RRAGB,RAB37,ARL4D,ARL6,SEPTIN6,RHOBTB1,ARL11,SAMHD1,EEF1A1,AK3,RIT2,RIGI,SRP54,KRAS,GIMAP4,RAP1B,EIF5B,GTPBP1,RABL3,RAP2B,EEF2,ARL15,GMPPB,GNAI3,DRG1,RASL10B,GTPBP8,DNAJC27,RAB6A,ARF6,TUBA1B,RAB33A,MX2,RASL11A,ATL1,ADSS2,RAB8B,GIMAP2,RND3,SRPRA,MAB21L1,TUBG1,EHD1,RASL10A,GTPBP2,RAB40AL,RAB6B,RAB2A,EHD3,RRAGA,RP2,TUBA1A,RTCB,MFN1,RTKN,RAB3C,OLA1,RAB28,RAB11A,TUFM,NKIRAS1,RAB27A,RRAS2,RAB14,RAB5C,RAB1B,RAN,RHOU,GNAI2,ARF4,RAB3A,RAB32,NME1,GFM1,ARF1,NOA1,MTG2,HRAS,RND2,RAB33B,RAB19,RAP2A,RHOB,RAB22A,GNAO1,RALA,RABL2B,DIRAS2,TRIM23,RAB13,SEPHS1,RAB9B,GPN2,RHOH,SCG5,SAR1B,RHOG,RAP2C,ARL10,NKIRAS2,MTG1,LANCL2,RAB29,RHOJ,RALB,UPRT,RAB39B,DAPK1,RAC2,SRPRB,MX1,GNA11,ARL5B,IFT22,RASL12,RAB5A,EIF2B2,PCK2,NPR2,RAB23,DNM2,THG1L,DRG2,RERG,AGAP2,RIT1,ARL4A,DIRAS1,RAP1A,ERAS,CDC42,CGAS,NUDT2,GNAQ,RAB11B,FKBP4,TUBB,AGAP1,HSP90AA1,RAB4A,GFM2,TUBB4B,RASD1,SEPTIN7,RAB30,SUCLG2,RAB3D,RAB18,RAB1A,GNA14,RHEB,RAB35,FPGT,GNAZ,GNL1,MMAA |
| 5.797e-09 | -18.97 | HNRNPF (heterogeneous nuclear ribonucleoprotein F) | protein interactions | 3185 | 556 | 218 | 19454 | 5460 |
PHB1,MIR7-2,FOLR1,MIR141,HYPK,CCAR2,NUP35,DHX15,PSMD3,MAP3K14,HNRNPA1,PSMD10,RB1CC1,MIR1-1,PDCD10,HNRNPD,HNRNPA2B1,SRSF7,HSD17B8,TNF,LASP1,PSMD12,B3GNT2,RAF1,PPP2R1A,CHMP4C,EZH2,SNRPD2,ACTB,TSN,NDUFAF4,MIRLET7D,CUL2,CUL3,MCM3,MIR98,BRCA1,ILK,MIR363,PSMA3,CRY1,MIR106A,KCND3,WDR77,PPP1CB,RNF7,VAV2,RCHY1,AIFM1,MIR106B,MIR25,DCUN1D1,KLF1,ZBTB2,NCBP2,EMC4,NFKB1,HDAC6,ECD,MIR34A,FAF1,VRK1,RNF20,FBXO25,FBP1,MIR200C,MIR15A,EEF1A1,MIR20A,MIR17,PPME1,EIF4A3,MIR16-1,CCNF,UBASH3B,RPS20,RAB14,NDN,VIRMA,DHPS,AR,FBXO7,IVNS1ABP,MIR145,NAPA,CDC73,SIRT7,MIR205,RPA3,MIR34C,MIRLET7I,FBXW7,MIR7-3,MRPL17,TXNL4A,RBFOX2,CDK7,MIR1-2,EDF1,METTL14,HNRNPH3,SRSF1,MIR214,EED,DYNC1I2,MIR9-1,SUMO2,HNRNPL,SMUG1,MIR143,WWP2,IFI16,DDRGK1,MIR29C,MIR31,AGR2,MIR140,MAGOH,HSPB1,PEX3,MIR221,MIR9-2,PABPC1,EWSR1,RPAP3,MIR206,RUVBL2,MIR155,KRAS,HNRNPF,TFG,HNRNPDL,SUPT5H,NCSTN,ISG15,TUBA1A,MIR222,SOX2,PLS3,MIRLET7B,SF3B4,PSMD6,PSMD4,MATR3,APEX1,PSMA4,MYC,PSMD1,BTF3,FBXW11,ZMPSTE24,OSGEP,DDX5,EP300,HDAC5,HSPA8,ADRB2,STAU1,ARHGEF39,HNRNPA0,UFL1,PPT1,PIH1D1,MIRLET7G,FZR1,CAND1,CDC5L,TMPO,MIR429,ANKMY2,PRR32,COPS5,SNRNP70,MAP4,TSNAX,MIR200A,SNIP1,DHX9,MIR9-3,HNRNPK,CSE1L,NEDD8,MIR16-2,MIRLET7C,MEPCE,TP53,UBL4A,ZNF581,CDK8,NUPR1,ACOX1,PSMC5,ADRM1,SMURF1,CDC20,STN1,RC3H2,RBM7,UBE2H,CDKN2AIP,BAP1,MIR10B,RNF113A,HNRNPH2,MIR107,HSPA5,MIR29A,MIR34B,CCNH,AGO1,NEK2,PLP2,GABRA1,RPA2,MIR7-1,UBE2M,MIR21,HEXIM1 |
| 6.038e-09 | -18.93 | ETFA (electron transfer flavoprotein subunit alpha) | protein interactions | 2108 | 276 | 122 | 19454 | 5460 |
SLC25A12,ACTA2,COX4I1,AIFM1,SSBP1,TMEM70,DNAJC7,GRSF1,PSEN1,FASTKD5,ARF4,SFXN1,EHD4,RAB1A,NDUFS3,GFM2,MRPL11,MTCH2,CMPK1,METTL15,PPIF,HADH,AURKAIP1,DDX39A,LDHA,DUSP3,VIRMA,SUCLG2,SH3BGRL,UQCRC2,CCNF,EIF2S2,SPOP,DNAJC19,SORD,NRP1,NAPA,CSK,RAB2A,CTSD,TUFM,ATP5F1A,AIF1L,YKT6,CRYZ,TOMM20,IDH3A,APMAP,BAP1,RPA3,GFM1,GPX4,EXOSC4,HSPB2,MTRES1,CDK7,CFTR,CDC42,NDUFAB1,RAB1B,RMND1,COX14,PPIA,GATD3,AGR2,SLC25A28,RHOG,AK2,GSTO1,MRPS26,DCAF11,HNRNPD,RAB5C,PIK3R1,MTRF1,ETFRF1,VDAC1,IMMP2L,RPL31,HSPD1,ZYX,COX8A,HINT2,PDHA1,RAB6B,EZH2,ETFB,RAF1,TOP3B,TENT5C,AKR1C2,ESR2,UBE2V2,MTG1,CCDC90B,TACO1,ARF1,ANAPC2,LAMTOR1,LDHB,CUL3,EPS8,PMPCA,MYC,MTG2,AUH,BAG3,GALE,ATG101,PHB2,EMC1,HSCB,EXD2,NGRN,DDX39B,HADHA,PMAIP1,AKAP1,HDAC5,HSPA8,PAFAH1B1,RAB6A |
| 6.156e-09 | -18.91 | PGD (phosphogluconate dehydrogenase) | protein interactions | 5226 | 167 | 82 | 19454 | 5460 |
NEK7,CDC42,LAP3,UBE2M,ACAA2,PPARG,RPA2,SQSTM1,TCEA1,HSPA8,PGK1,RPA3,BAP1,LSM8,OXCT1,UCHL3,HMOX2,TXNRD2,LDHB,MYC,RIT1,UBE2H,SORD,MDH1,CDC73,OAT,ATP1A1,BRCA1,CHCHD4,CHORDC1,MSN,DLST,CCNF,ACOX1,MYG1,TUBB,ACTB,LDHA,EIF4H,EEF2,SOX2,ISG15,GBE1,CDK4,GNAI3,CHMP4C,RAB4A,EZH2,CBX3,IDH1,MRPS11,HINT2,SDHC,PAK6,RIGI,DUSP21,PSEN1,MRPL22,ETFA,TF,KRAS,HDAC6,ATG7,YWHAG,ISYNA1,MRPS35,MOV10,PDIA3,YWHAB,PYURF,AHSA1,DNAJC7,AGR2,GSTO1,HEBP1,AKR1B1,CD274,FABP5,CAV1,G6PD,SUMO2,SUMO3 |
| 6.186e-09 | -18.90 | regulation of cellular metabolic process | biological process | GO:0031323 | 6375 | 2047 | 18204 | 5365 |
PLD3,PARM1,MAP2K3,DUSP3,MIR192,LRP3,SESN3,RERE,ZNF596,MIR9-1,SCAND1,LSM2,OTUD7B,RPRD1B,RFC2,DKK1,MIR600,MIR367,GLRX2,HOXB1,CCR7,RNF8,STAT6,C9orf72,HAND2,PRDM4,MBD3,SRSF7,LCORL,ADRB2,DDX4,CD200R1,EIF4EBP2,FKBP1A,MIR339,CDC5L,TRIM29,PRPF19,PELO,ING5,NR1I2,PPTC7,SAP30L,IRF8,CCR1,NUCKS1,MIR558,HOXC4,PAEP,DHRS7B,CSNK2A1,CPEB1,HNRNPA0,GHRL,BAG3,NDFIP1,CBL,SART3,RHEB,SOX9,SNAI2,MIR489,ZNF7,RBM23,DCAF5,DLG3,RORB,DMTF1,CCL5,DYRK2,AKAP12,RPS14,TRIM68,TLR3,MIR3173,MIR761,MIR484,MIR302B,FLCN,ZNF652,FZR1,DUSP19,NUPR1,SECISBP2L,AGO1,CRYAB,HNF1B,MIF,IL12A,MIR132,BCL10,RWDD3,EIF5A2,MAP3K12,HEY2,IRF3,SETD7,RNF34,MIR1225,ZNF518B,KLF12,STK3,PARD6A,MIR101-2,CHID1,GPBP1L1,CPTP,MIR452,SWAP70,SPIN3,TADA1,LANCL2,MIR150,RUVBL2,DKK3,ING2,EFNA5,MDC1,THAP1,MIR662,MIR504,IL4,ILF2,FAM98A,SCML1,DGCR8,NKRF,MIR146A,CAMK2N1,NGRN,ANKRA2,ATP6V0E1,MIR1298,CX3CL1,MUL1,FCGR2A,MIR624,MID1IP1,ING1,PHB1,FGF7,DNAJC10,STUB1,MIR615,PLAC8,CDK5,HEXIM2,MIR98,KDM2A,RNF5,MIR649,PKIA,CCT8,DUSP10,MIR628,GTF2A2,SUPT5H,TENT5C,LSM14A,TOP1,MED4,MIR105-1,MIR16-2,CDKN1A,MDFI,RNF152,ILK,TMEM107,RPL6,EID2,ZNF655,TAFAZZIN,NLRP2,MIR301A,ZBED4,ZHX3,PPM1D,MIR214,H2AB1,MIR502,YWHAB,NLRP3,CLDN3,CASC3,H1-5,IRF4,FUT8,PDCD1LG2,MIR552,HENMT1,SDCBP,MIR188,MDM2,MIR583,TP53,MIR1-1,DDX5,NCBP2,ZNHIT3,TIMP4,ZNF473,BAG2,PTPN1,INTS10,HSPA8,CSRNP3,PAX9,MIR147A,ZNF790,JADE1,CER1,DLG4,MIR335,LGALS3,ZNF692,WDR6,KPNA2,ZNF189,CYP27B1,TRIM15,ZBTB14,PIWIL1,FAF1,MIR195,ZNF526,ZNF326,DROSHA,MIR1249,HEXB,MIR198,TRA2A,TRIM52,CDKN1B,MIR218-2,MIR193B,HOMER3,FOXJ3,RBM15B,UFL1,RBM3,SCFD1,CLK4,SAP30,NFKBIA,BRD9,PPP1R11,SPRED1,SNX18,TCF23,MIR331,SIRT7,BAK1,VDR,TEF,MIR877,ZNF688,MIR345,CEBPE,MIR374A,WNT7A,VSTM2A,SIAH2,TGFB3,RPS4X,DUSP26,ACO1,FUBP3,CCT7,RPL26,SERTAD2,ITGA2,TCEAL1,TAF11,PHC1,ACP5,FGF1,MIR125A,GNB3,PCSK9,MIR187,NRP1,PRKCE,MIR450B,RGMA,ATF1,PARL,DIO2,SMU1,MIR10B,MED13L,XBP1,RPL13A,TERC,PID1,CCND1,HIRA,TSC22D3,PAIP2,IL2,MIRLET7B,CYTL1,PAK2,TRIM63,MIR130A,AR,SOD1,MIR492,CNR1,GNRH1,MAGEC2,MACIR,ZNF513,UBE2K,MMP14,ZBTB2,EIF4E,TP53INP1,ZNF581,ID4,BAHD1,PTP4A3,CHMP1A,PADI2,PPP2CB,PPP1R12A,ACTL6A,FOXP3,CD274,AKT3,DRAM1,MIR1224,HAX1,SPRY1,E2F4,LMNB1,CLIP3,PAFAH1B2,TENT4A,SMARCE1,KLHL25,SMYD3,GFPT1,PAX6,RIGI,MIR577,WNT10B,TXNIP,OPTN,HP,TP53INP2,MIR887,MIR454,PRKAG1,SMARCD3,IFNK,HDAC3,ZNF24,MIR148A,ZBTB16,MIR383,NACC2,LCP2,SFN,DNAJB6,EHD4,TNIK,ZNF507,MIR96,MIR648,VSIR,APBB3,MIR363,MIR101-1,TRMT112,UBE2L3,GPAM,TRIM32,ZSCAN25,MED9,MAGEA4,SERTAD1,MED23,LAMP3,CNOT6L,RASD1,HILPDA,FGF16,SYK,PITHD1,NLRP1,HNRNPL,BOLL,PRDX6,FBXW7,EWSR1,PRR5L,EAF2,S100A8,TESC,NOG,APOBEC3C,SELENOT,MIR129-2,MALSU1,TRIM5,IGF2BP1,NPPC,PHF23,PSMC5,CLEC9A,CHCHD2,CCL2,DUSP6,DNAJC1,POU1F1,EIF5B,ARL2BP,JMJD8,RBM42,CIART,PDE2A,SERTAD3,APOBEC3A,C1D,MIR373,RARRES2,G6PD,H2AC1,MYLIP,ZNF287,TACO1,PIAS1,DIRAS1,VAMP3,XRCC5,CYRIB,TBK1,CDK4,MIR632,MIR32,ZBTB39,FEZ1,TAF1D,TAF10,IL17F,CD47,PIK3CA,ZC4H2,NTF4,TCIM,APEX1,ROCK1,SUPT4H1,MIR15A,PHAX,H1-3,CCDC85B,RB1CC1,KLF3,CSH1,CD58,THY1,MIR939,TFEB,MIR140,PDE4B,CD40LG,RNF41,NSMCE3,EIF3E,FGF23,MTPN,NUDT16,PRELID1,PPM1B,CLK1,IL23A,MTA2,CTSA,VEGFA,TIMP1,SATB1,ZNF704,MIR944,PIK3R2,KLF1,MIR301B,OSM,CCL1,YWHAZ,PRKACB,DEK,SOX14,FZD4,KRBOX4,CAPN2,CAMK1,CRIP1,RASL11A,DBNDD1,NOTCH2,SVIP,SRPK2,RBM7,HNRNPH2,ACTA2,CRYBA1,CHP1,TGFB2,MIR144,METAP1,PAK6,RING1,SEC22B,PCNA,MIR612,ZBTB38,SPRED2,MXD1,IRF2,RAP2B,USP13,TRIM37,PDE8A,NFKBIB,SOX2,PTPN22,PXYLP1,FMO1,ABHD14B,HSBP1,CDH13,PIWIL2,CCNQ,SNX33,MTDH,ADTRP,GREM1,MIR940,ATP2B4,MMD,MACROH2A1,RIT2,MIR708,PAGR1,ZNF174,ZC3H14,SHC1,CTBP1,PRKCB,TRAF3IP3,ZNF250,TADA3,NFE2,CIRBP,PRCP,CCL21,HBP1,MIR20A,BAZ1B,ATP1B1,CDK7,MAFG,CISD1,DNAJC19,FMO2,DNAJC30,ATP6V0B,SPON1,G3BP1,GLO1,THOC2,WWP2,MIR216B,HNRNPA1,FRMD8,CREB1,IER3,IFNAR1,MIR556,APOBEC3G,TDRD7,PRDX3,SASH3,CD83,PSRC1,MIR190B,GATAD1,HTR2A,INPP5K,SAP30BP,KLF9,APLN,MOV10,SMAD5,SOCS4,TGIF2,HSP90AA1,WDR45,CDK5R1,KDM4B,MAGED2,H2AC13,SP4,TRIM11,ATP6V1A,SMG5,RC3H2,ERLIN1,FKBP1B,VGLL4,CD28,TAX1BP1,HSP90AB1,CBFB,MEF2C,BEND5,CAV3,MSTN,ZCCHC17,IFIH1,MIR208A,PKIG,GFI1,ZMYM2,CNKSR3,ZMPSTE24,RUNX1,TAF2,WWP1,ZGLP1,HBEGF,ZBTB42,TRIM26,AP2A1,LILRB4,RPS27L,ARB2A,EGR2,PPP1R2,FGF17,LBH,ADIPOQ,H2AZ1,YAF2,MIR567,ROCK2,NMBR,TRAF2,CBX5,FOXP4,ETF1,EEF2,RPS3,TRIM6,YTHDF1,MIR495,CORO1C,CXXC5,EPHA2,ZNF770,INO80C,LARP4B,S100A10,CAB39,MIR361,ZNF304,MIR23A,AGER,PLEKHF1,BATF,TNFRSF14,CXCL10,PSMD10,SPHK2,JPH4,CIDEB,ZNF622,RAG1,FBXW11,H2AX,SPINDOC,MIR424,OGG1,TRIM23,MTRES1,DIS3L,TFDP2,DDR1,STK38L,XAF1,LDB1,CGGBP1,EXOC8,MIRLET7C,HSPB8,MIR657,ACOT8,MIR1277,RHOH,MIR581,DIPK2A,TAF7,IDO1,SPPL3,TENT5D,MITF,VPS72,ZNF451,KCTD20,CLEC7A,IL21,MIR216A,MIR34A,ZNF671,IL13,MIR609,VASH1,ATXN1L,FGFR1,HELT,PTPRQ,ACSS2,PIWIL4,VGLL2,SCAMP5,MIR155HG,ENC1,CKS1B,HDAC11,PTPN11,HUWE1,GHITM,FOXI3,NONO,CDK6,TFPT,TRIM27,RAD21,LSM6,POLR2L,SLC6A4,TGFB1I1,MYRF,GAPDH,MIR934,CNOT7,ESR2,FZD6,RFXAP,EZH1,MIR1262,ITK,IL7,IER2,TSPO,BTG2,ZBTB6,RNF20,RAP2A,DCP2,RNF187,JUP,GPNMB,MIR711,SP1,CYP7A1,MIDEAS,MIR626,PTGER4,CCNA2,RAB39B,SFRP4,RPL23,EP300,RFC3,WDR77,PIK3R3,OVOL1,BOK,BACH1,ANXA7,TMEM106A,CCNI,LSM14B,GPX1,ZNF862,LMNA,ZMYND11,GMNN,AKAP17A,MIR136,PRMT5,MIR99A,H2AC6,MIR92B,GRB10,TANK,SELENOS,MIR9-3,DRD3,MAF1,PKIB,MIR573,BST2,TSPAN15,TIRAP,KPNA6,RAMP3,PPP1R8,GSK3A,BAD,DEDD,AATF,SNX12,ODAM,MIR206,MLLT11,H2AC4,MIR643,CDK12,CTDSP1,PHF21A,TRIM24,DIRAS2,CRKL,MSN,FOXP1,STOML2,MIR190A,POLR3B,PCBP4,MIR185,DUOXA2,IL12B,RNF14,UBE3A,USP2,RSAD2,MIR1-2,ZFP64,BGLAP,MIR107,MORC2,PPP1R17,PNP,JUN,HSPD1,MIR885,CBX3,ROPN1B,VDAC1,MTA3,MIR449A,FLOT1,ZFP1,EMX2,CXXC1,ELK1,LYAR,SIN3A,EIF4E3,RRAGB,POLR3F,MIR210,MIR593,MIR33B,POU5F1,MIR197,H3C1,RMND1,ZNF592,MIR651,ABCC2,ILDR1,ZNF280B,MIR548C,POGK,MYBL2,EXOC1,TIA1,RGCC,LILRA2,MIR375,MSX2,INHA,MTG2,MIR30B,RBFOX3,MIR519D,ELF5,ATG16L1,SLC7A11,SCML2,SMAD3,MIR24-1,ISCU,CSRNP1,DUSP22,TAF9,HNRNPD,WNT2,CCN3,EIF4A3,KMT5B,IRF2BP1,TRIM62,TMIGD3,SELENOK,MIR205,SETD5,RALB,MIR599,MIR924,PCGF3,KLF10,ATF3,ELP3,ZNF32,FCGR2B,MIR653,STAP1,IRF2BPL,PRSS37,CHI3L1,PSPC1,FOS,RPAP2,HNRNPF,ARG2,TESK1,ZKSCAN1,LRIF1,NFKB1,MIR937,LIPT2,SUPT3H,PLP1,HLF,MIR1180,MIR181D,NUDT12,MIR802,POU3F4,TRAF6,CCNF,TICAM2,HP1BP3,MIR222,HOXD12,CCL19,TRIB1,MIR378A,TMEM59,RNF40,PLAGL1,BIRC5,TENT2,ZBTB5,IFNG,TAB2,MEF2A,PRKRA,MIR135B,TOM1,USP30,LGR4,PTGES3,NRDE2,MTMR2,SRGN,SRC,ADRA1A,MIR34C,CDK20,ZNF609,ANGPT1,PPID,HEXIM1,ATF4,TRIM21,NOVA1,HNRNPK,ZNF22,SMAD9,AKR1C1,TICAM1,MIR181C,MECP2,MIRLET7I,BMPR2,MIR29A,BNIP3L,EDC3,TAL2,MIR542,MOG,LYPLA1,EXOSC3,CELF6,IRF1,ITM2B,PQBP1,INSM2,AFAP1L2,UTP15,IFI16,CCT5,LMO3,MIR551A,STARD4,NTRK2,CTNNBIP1,ACTR2,METTL14,TCEAL7,NBN,MIR346,MIR449B,NEDD8,MIR370,RLIM,OSBP,MIR597,LTB,TLE1,TRIM8,FBLN5,MSL2,MIR517B,ATP6V1C1,MIR30D,DHX9,SPP1,FAM20C,MIR25,BTBD10,RABL3,UAP1,ISG15,THAP7,ZNF501,BHLHE40,MIR1226,HCFC2,ZNF345,RGMB,IL5,EDF1,BUD23,TSN,TLR7,MIR29C,ZBED1,KDM1A,MIR936,TOB2,STPG4,PRMT2,HGS,HDAC5,MIR511,MAP2K1,PPP1CC,FCGR1A,MIR488,ANKRD49,IL1R2,EXOSC4,SUB1,RGN,MIR551B,MIR429,STAT2,ZCCHC7,TOPORS,BECN1,FIS1,DICER1,IKZF5,DNAJB9,BANF1,MIR215,DLG1,IGBP1,SF3B5,CNOT6,ZNF322,MOSPD1,DEFB124,MIR605,MIR200A,EPHA4,MIR7-2,PELP1,ZNF821,MIR942,FERMT2,CSNK1E,RBM12,TIMP3,IGF1R,MAGEH1,SFRP1,RTRAF,PPIA,YWHAH,ID1,CCL3,TPD52L1,LILRB1,GTF2F2,IL6ST,BTN2A2,ETFBKMT,STOX2,RFX4,CSF2,ATP6V1D,BARX2,SRSF12,FASTKD5,EEF1E1,MIR876,MIR661,TYROBP,MAVS,ZBTB17,MIR760,FURIN,KANSL3,RPS9,TOX4,HTRA2,BEND6,IL20RB,SOCS5,HSPA5,MYD88,TAF5L,NPTN,MIR149,CD46,ZNF436,IGFBP3,ARPP19,NLRP9,CD81,TULP3,ACTB,HMGA1,FGF3,TWSG1,MIR9-2,TNF,SHMT1,BRMS1L,SF3B1,RBPJ,XCL1,NAB2,SLC25A4,AVPR1B,CDK8,MIR191,ATP1A1,PDE12,RUVBL1,EDA2R,TOP2B,ORMDL3,HMG20A,SSU72,HFE,CTDSPL2,PFDN5,BCL6,SH3BGRL,BCKDK,ELAVL2,EMILIN1,MED11,MIR1296,FBP1,ABHD5,ITGB8,HINFP,TCF19,ZNF511,LURAP1,IL1RAP,MZB1,RIOX2,NFYA,NDN,DRGX,RBM5,TMEM39A,TMSB4X,CDK9,SDR16C5,PHF12,MIR338,NAB1,TYMS,RNF141,SLC25A5,CITED1,RB1,GJA1,MIR17,MIR764,RBM38,CNTN1,PAIP2B,CEBPG,FOXC2,AIF1,NEUROG2,ACTL6B,MIR671,GNAI3,CIAO1,STK4,MAEL,EPOP,SOST,MAP3K3,ZNF362,LEPR,SOD2,NEK7,ZC3H7A,ASCC1,PCGF6,MIR99B,CNOT8,ITGAV,SAP18,ZNF574,MIR26B,TRIP4,CRABP2,PCGF2,GHR,CIAO3,RAP2C,ZBED3,KLF4,TGIF2LX,ARF4,TLR4,APLNR,RNF139,C1QTNF1,HMCES,HINT1,ZNF668,MIR638,LUM,RBCK1,TRIM44,APOC2,RPS26,B2M,IFRD2,PRIM2,EIF2B2,LHX2,TCEA2,GTF2I,KLHL22,PLGRKT,HELLS,IMPACT,MLF2,SUV39H1,SUFU,RHOG,MIR212,MLF1,MIR503,APOBEC3H,EPCAM,ROMO1,PTRH2,DKC1,IGF1,MIR604,HMX2,ENY2,WTAP,CNOT2,GRSF1,MIR675,ATP6V1G2,SKIC8,MIR639,CALR,TNFAIP3,GH1,RBBP4,GSTP1,MAX,TXN,NEUROD6,INPP5E,CREB3L4,MT3,MXI1,TOX,CCND3,ELAVL4,MIR182,SLC45A3,PPP3CA,CLP1,DYRK1B,MIR569,AKT1,IL1B,ZNF787,IFNA13,MTERF2,SLCO3A1,TLR6,AGR2,EXOSC8,EIF4B,MIR595,MIR211,E4F1,TSG101,NR1H2,CDK5RAP3,ZNF343,MIR448,TSPAN5,EIF4A2,MIR1251,MET,MIR631,MIR320A,FAS,KIT,PHF1,TGFBR2,UBE2D1,HNRNPAB,MIR223,G3BP2,NKX3-2,ELF1,ERLIN2,FCER1G,DDX1,TBC1D25,MIR379,BAX,TRAF3IP2,AGPAT1,TOM1L1,IL6,EFCAB7,MOB3B,IFNA10,LSM5,GNAQ,PAIP1,MMP9,PYDC2,CD86,SOX21,VPS26B,PSMA6,AKT2,COPS2,MPV17,FOXN2,UHMK1,HMX1,MATR3,ERRFI1,PRNP,MIR130B,CARHSP1,SF3B4,MIR589,GPR137,MIR607,DAPK3,SSBP3,MAD2L2,IKZF2,CLEC6A,MIR204,ZNF576,MIR423,ZBTB33,FOXS1,NMI,DSTYK,GABPB1,UCN,TAPBP,ANXA4,CD80,MED27,GTF2A1,KCNIP3,ORMDL1,TNFRSF1B,TLR9,PLCB1,MIR196B,MIRLET7D,MLLT6,ADM2,E2F6,PPP2R5A,SMG8,METTL18,MCL1,RPL10,MIR580,CDKN3,CDC73,MEF2B,IFNA2,DNAJC3,FABP4,SPTBN1,NIF3L1,CD2,TCEA1,ATRAID,WEE2,TNRC6C,ASB1,HR,NPC2,PRKAB1,LACRT,STAR,YES1,BIRC2,DUSP1,NR1I3,MED10,ACVR1B,CD40,TMBIM6,NME2,FOXA3,MAGEB1,POLDIP2,MIR616,SGF29,HDAC6,INTS12,MIR208B,ALKBH4,CREB3,STK11,CCAR2,MIR592,MED22,NHERF1,MAP2K6,H2AC25,MRTO4,MIR7-1,ZNF805,NUP62,MAPKAPK5,WBP2,DRD1,PIH1D1,RDH10,MIR16-1,ZNF575,MRPL12,MRPL13,HNRNPDL,CCNH,GTDC1,TLR2,MIR183,RPS13,CYP1B1,PTHLH,AKAP8L,RNF10,RNF26,VRTN,STAT5A,VIP,PPIF,IFT52,CBX7,CACUL1,MIR139,PDCD4,STAU1,NEO1,CAMP,MAGOHB,ETV6,MIR143,MIR891B,MIR572,GTF2H2,IL18,ELK3,UQCC2,BZW2,WRAP53,EID1,PIK3CG,HNRNPA2B1,FASLG,INSIG2,TLR1,MIR769,IL15,MIR137,MIR194-2,MIR455,MIR298,BCL9,FABP5,MIR532,MIR652,SLC38A2,CEP85,NF2,MIR874,CCAR1,NR2E1,PIK3R1,RAN,ATP6V1E2,MIR24-2,CUL3,SETD4,NR0B1,MIR922,FOXP2,MAGED4B,MIR30E,ELK4,MIR218-1,TCP1,H2AJ,NIBAN2,ISX,CCNB1,CRYM,MIR493,TRUB1,KRAS,DPY30,IL1A,PPP1R3C,FGF10,TF,NCK1,IRF6,IL2RG,GCLC,WASL,ATP6V1G1,DYRK1A,ZNF177,MIR152,KLK3,DDIT4,PROX1,CREBBP,TNFSF18,MIR147B,ZBTB18,SMAD1,MIR200C,CCT2,MIR425,IRF7,NLRP6,ACTN4,MIR1260B,ZSCAN1,ZBTB26,XPO5,FOSL2,LTA,COPS5,SUMO1,CDCA7L,DIRAS3,OAS1,SETD3,IDH1,TWIST2,HNRNPC,TRIM22,MIR656,MTF1,AIP,LITAF,PICALM,PYM1,MIR106B,CASK,FITM2,GPSM3,ITM2A,LRRC14,DLX1,SSBP2,MIR184,MYC,MIR126,MIR553,DAPK1,MARS1,MIR142,MIR490,HSPB1,PDCD5,MIR105-2,APOBEC3D,DDT,OSR2,RPS6KA4,MIR194-1,ATP6AP2,CDK1,SNIP1,CHRM5,MIR557,NFIL3,MED21,EED,CTDSP2,TNFSF8,PPP1CB,MEPCE,CAV1,IFNB1,RBBP8,SOCS3,TNKS,TAB1,RBFOX2,MEAF6,MTG1,PIM2,CDKN2D,RAB1A,AGAP2,NDUFA4,SUPT7L,RBM22,IRF9,ZNF397,CYP2D6,MIR342,SMAD2,MIR31,BUD31,BRCA1,ALKBH5,SLC38A3,UBE2I,APOBEC3F,IDE,ZNF687,SNRNP70,ZHX1,MIR324,CD4,MTM1,PSEN1,TNKS2,DDRGK1,MAP3K11,MIR636,NAA15,MIR505,RBBP7,CRLF3,POLDIP3,ARMCX3,RAF1,SRSF2,STN1,PTGFR,MIR611,FERD3L,IL10,MIR640,TRAF1,TAGLN3,CDKN2C,NKX6-2,RFC5,MIR145,CX3CR1,ZSCAN5A,MSX1,PPP1R1B,LY96,BCL7B,HMGB1,RGS2,LBX1,SSBP4,MIR875,HNRNPH3,BCCIP,GABPA,GTPBP1,PYCARD,HRAS,INPPL1,ZNF593,HSP90B1,RFC4,SH3GLB1,APOBEC3B,USP16,NFE2L1,BHLHA9,TRA2B,ZBTB45,DAP,CGAS,STRADB,ADNP,CTTN,PRKCA,BRD3,EIF4E2,ACVR1,PIP4K2C,POMT2,F2,CCR2,BCL7C,PLSCR1,CAPN1,CCNY,MIR133B,RRAGA,CXCL8,FKBP8,ITGA6,MIR770,UBP1,UBE2D3,ATG101,NKAP,MIR340,SRSF1,P2RY1,PRDX2,RAC2,ADORA1,ADORA3,SIX5,FGF22,SMG9,TOMM70,MIR590,MIR586,DNAJC2,POLE3,DDIT3,MNAT1,NR4A2,MIR28,ZNF664,EPO,IL34,IKBKB,CHCHD4,EGR1,MIR422A,MKKS,YTHDF2,NFYB,MIRLET7G,NCSTN,EIF4H,EZH2,IL3,UPF3B,MIR554,CHRNA7,UFD1,F11R,MIR193A,SESN2,MIR106A,SLA2,PRKCQ,FAXDC2,PGR,ZNHIT1,PPARG,EMX1,CCDC22,PAQR3,MIR30A,MIR384,DR1,SNX5,MAGOH,PDCD10,EIF3D,NAA16,PACSIN3,KARS1,SP2,SLC1A1,CTNNB1,HYAL2,SHLD1,MIR1227,GPT,TSNAX,H2AC7,KLK5,MIR1271,EID2B,UBE2V1,MIR578,NOP53,TNFSF15,MIR938,RNF128,LSM4,VPS26A,SMAD4,INO80E,MORF4L1,MED31,MIR500A,FBXL19,LMO2,MCPH1,JAK2,PTEN,STAT1,USP3,CAND1,LRP6,LACC1,DVL2,CRY1,DEFB114,SMCHD1,CD34,ABCE1,RAB27A,RIOK2,TNFSF13,MIR377,CREBZF,LMO4,GRIA1,CD14,EIF2AK2,GNAI2,RLN2,SS18,MIR221,ATP5IF1,MIR155,PSMC3,RRN3,MIR497,CARTPT,UBE2N,SLC8A1,NCOA5,THRAP3,YWHAG,LDB2,RNASEL,FGR,ERP29,RFX5,CSK,MIR633,GTF2F1,BTG1,ZNF267,PRL,TRIM34,MIR186,OTX2,JUNB,HAS3,ENO1,LDLR,DMAP1,MIR10A,NEUROD2,ZNF263,EEF1A1,IFNGR1,RXRG,PELI1,PPARA,VEGFC,PC,MED29,IFI27,BAP1,CD36,RBBP9,MIR129-1,SRSF10,IREB2,DXO,TCF21,FOXD3,MOB3C,DNM2,EMP2,MIR330,SYNCRIP,NGDN,CREBL2,TSPAN17,DHRS4,CPNE1,ANAPC2,ELP6,WDR82,MIR21,ECD,COX7A1,CKS2,NR2F6,PCBD1,MAGEB10,CRTC2,TUSC2,PNRC1,RAP1A,MIR920,SERPINB1,ELOC,TFRC,MIR23B,CLU,MACROH2A2,MED30,OTULIN,NFKBIL1,NKX3-1,RPS7,PKNOX1,STK38,TFCP2,BMPR1B,HCLS1,PML,EIF2S1,SNAI3,MIR491,TERT,MIR141,PABPC1,NEK2,CD38,CD2AP,GSKIP,FXR2,GADD45A,CAMK2N2,ZBTB25,NDP,FKTN,H2AZ2,SFTPD,TLR5,MIR34B,DYNLL1,MIR873,MIR7-3,MED17,STK16,HOXB8,MIR765,SH3BP4,PIWIL3,ZNF740,EIF1B,SMARCA5,PHB2,TCOF1,ZNF175,MIR148B,SLC25A23,MIR601,CD200,SQSTM1,LEP,POLR2G,COMMD6,COX17,PRMT6,MPV17L2,SOX3,FBXO7,NFE2L2,DNAJB4,BMPR1A,SMARCB1,MIR549A,DRAP1,TFE3,SEMA7A,UBASH3B,SRSF4,MIR625,GTF2IRD1,MIR100,BRMS1,TRIM3,MIR296,TLR8,CIPC,MYT1L,NTRK3,ZNF319,CCDC3,MIR563,MIR618,RFXANK,EIF3K,EIF2B5,EIF4EBP3,MIR153-1 |
| 6.213e-09 | -18.90 | TOE1 (target of EGR1, exonuclease) | protein interactions | 114034 | 141 | 72 | 19454 | 5460 |
NSDHL,RPL31,EWSR1,RPL23A,RPL3,LSM4,KRAS,H1-6,HNRNPF,SNRPG,SRSF4,RAF1,CD2BP2,H1-3,IK,LLPH,EZH2,SNRPE,SART3,KRR1,IFIT2,PRCC,PRR3,SNRPA1,SNRPD3,RPS10,CAND1,RPS16,EIF2S1,SURF6,WWP2,DDRGK1,SNRNP70,RPS2,PRPF4,SNRPA,RPA3,PYM1,SQSTM1,EP300,STAU1,UTP23,SUMO1,FGF17,SNRPN,CA12,ATG16L1,WDR83,WDR77,H1-5,RBMS2,AGGF1,RPS3,RPS9,SNRNP40,FBXO22,SNRPB2,SRPK2,RPL19,ESR2,CIAO1,CUL3,RPL7A,MYC,SNRPB,RPL26,ZNF668,CCDC22,H1-1,UBE2H,PIM2,AP2A1 |
| 6.229e-09 | -18.89 | STX8 (syntaxin 8) | protein interactions | 9482 | 218 | 101 | 19454 | 5460 |
VPS18,SEC62,OTULINL,GOSR2,BET1,STX7,RP2,GOSR1,RAB5A,JAGN1,ZMPSTE24,TMEM179B,SCFD1,RHOB,LAMTOR1,SCN3B,RNASEK,SEC61B,RETREG3,AP2M1,TMEM14B,STX12,RAB4A,VAMP2,DNAJC25,TMEM59,MED9,RAF1,ERRFI1,VAMP8,KRAS,GJB1,HECTD3,TMT1A,STAMBPL1,STX1A,RHOG,NCR3LG1,PLPP4,FAM174A,RAB5C,MDFI,LAMP2,ATG9A,TMEM237,VAMP7,CX3CL1,STX5,USE1,PTP4A2,LMNA,CDC42,SEC22B,FUT8,ATG16L1,LPAR1,NAPG,YKT6,DERL1,RAB9A,RHOU,NAPA,STXBP6,VAMP5,NDUFAF2,CREB3,MGST2,RHOJ,MGST3,STX10,AMIGO1,CLDN9,TMEM74,KCNMB1,ELOVL4,VAMP3,AP1S2,ACVR1,TFRC,TMEM205,DDX39A,CENPM,SNAP29,STX11,SRPRB,NOC4L,STX18,AQP2,STAR,MED21,LAMP3,DPP4,STX6,EIF2B5,FNDC9,VTI1B,RAC2,CLN8,MCL1,HSD17B11,SSMEM1 |
| 6.351e-09 | -18.87 | LBR (lamin B receptor) | protein interactions | 3930 | 279 | 123 | 19454 | 5460 |
LMNB1,YWHAZ,CHTOP,ARHGAP19,FAS,LSM14B,MYC,RPL10,ERH,MAD2L1,CBX5,DLST,LMBR1L,S1PR4,SEC61B,RMDN3,VAPB,CSNK1A1,PGRMC1,KCND3,OTULINL,PPP1CB,RND2,SEC62,ARHGEF39,UFL1,PXMP2,STX7,RHOG,HSPB1,YWHAB,RB1CC1,VSTM4,RAB5C,LAMP2,PSMD3,DDRGK1,YWHAH,YWHAG,HYPK,DHX15,EGLN3,PHB1,FBXO32,ARL11,RAB35,BRD9,MAGED2,EED,PDHA1,STIM1,RPN1,PLD3,RAF1,DNAJC25,TUBA1A,CDK20,CHCHD2,ARL5B,KRAS,G3BP1,SAR1B,UBE2A,RPL28,LSM14A,TMT1A,MECP2,SYP,UBE2H,PPP1CC,DEPDC1B,RHOJ,COPE,SRPK2,SEC63,EIF4A3,CCNF,SSR1,GRM2,LMNA,RPA2,HAUS2,HEXIM1,ST7,H2AB1,CDC42,FBXW7,RPA3,RAB9A,DERL1,PRKCB,ESYT1,AKAP8L,FAM20C,SLC25A46,HDAC6,CD81,PRNP,DNAJC1,ARF6,ZBTB2,LMAN1,CDK9,TMPO,ARL10,CD274,PTPN1,RAC2,HSD17B11,MAD2L1BP,CBX3,PRM1,RAD1,ILF2,TP53,CCDC47,LBR,RAB3B,H3C1,FKBP8,RPL17,MEPCE,DHX9 |
| 6.744e-09 | -18.81 | PDCD4 (programmed cell death 4) | protein interactions | 27250 | 162 | 80 | 19454 | 5460 |
HECTD1,EMC9,METTL14,LMNA,RPA2,ETF1,WDR77,G3BP2,POLA2,PSMC1,NPM3,TRA2B,EP300,SQSTM1,PSEN2,RPA3,H1-1,PDCD4,DTL,LMNB1,FBXW11,CKB,EIF3G,UFD1,BTF3,H2BC9,PSMD1,NCKAP1,PSMB6,NR1H2,ACTB,EIF4A2,INTS12,PRMT5,SNRPD1,PSMC5,EIF3K,EIF4A3,UBE2S,CCNF,PSPC1,APEH,AAMP,SRP72,PSMC3,RPS11,DDX39A,MAP2K3,PPP2R1A,SUPT5H,COMTD1,TPD52,H2BC14,PSEN1,RPS13,HNRNPK,UBE3A,HAPSTR1,TOP2B,TOPBP1,DRG1,SMCHD1,API5,YWHAH,HNRNPA1,CSNK2A1,YWHAG,CD81,XPO1,WWP2,CEP19,RBM42,SUMO2,PAIP1,RPS16,HNRNPL,SPPL3,RPLP1,MAP1LC3A,THOC2 |
| 6.744e-09 | -18.81 | PSMD8 (proteasome 26S subunit, non-ATPase 8) | protein interactions | 5714 | 162 | 80 | 19454 | 5460 |
FOXN2,KRAS,PSMA5,PSMA1,HUWE1,PSMA2,SEM1,TRIM26,SOCS2,PSMD12,ABCF1,PSME1,UBE3A,DHX9,ABCE1,TMEM31,PSMC3,RAD23B,ISG15,ASPM,PSMB9,DYNC1I2,FZR1,PSMB5,PSMB4,CD274,PSME2,PSMB1,PSMD7,PSMD10,TUBG1,CCDC92,SMAD9,PFDN5,PSMD3,DDRGK1,SHC3,DESI1,HNRNPA0,UFL1,RNF11,PSMC1,DVL2,BAP1,RPA3,PRDX6,PSMA3,EP300,TXNL1,GRM2,RPA2,PSMB7,PSMB3,PSMC4,UBLCP1,CFTR,PAAF1,PSMD6,ADRM1,PSMD4,VIRMA,MAD2L1,PSMB6,PSMA6,LMBR1L,CCNF,RPS12,PSMC5,GSK3A,PSMD14,BBS5,UBE2H,ANAPC4,SMAD2,PSMA4,PSMB2,USP14,BAG3,PSMD1,BTF3 |
| 6.808e-09 | -18.81 | RBBP6 (RB binding protein 6, ubiquitin ligase) | protein interactions | 5930 | 202 | 95 | 19454 | 5460 |
EZH2,NLRP2,RHOBTB1,KRAS,UFM1,TRIM37,SRSF4,SSRP1,PCNA,EWSR1,SRSF7,DDX23,ANKRD50,PRPF19,ZCCHC10,TRA2A,ZNF576,FOLR1,CLK4,EED,VAV2,LARP4B,PABPC5,SAP18,SNRPA,NUBP2,EP300,NUP50,DCAF4,RIT1,MYC,HNRNPC,CUL3,CPSF2,SNRPB,SNRNP40,PPP5C,MAD2L2,ESR2,CPSF1,NFKBIA,CBX3,CAPZA2,RBM34,ACOT13,CASK,H2AJ,TBK1,TP53,ERLEC1,THRAP3,RIGI,SMN1,GLUL,PSME1,SPP1,SNRNP70,BRD3,CD81,HP,PLG,THOC1,TOP1,NCBP2,MDM2,CDC5L,RB1,RPA2,WWP1,TFIP11,ATG16L1,RPS14,SF3A1,CPSF4,TPT1,PIAS1,RPA3,NLE1,ANAPC16,CLK1,RNF113A,RC3H2,ZBTB38,PPIG,UBE2H,CIAO1,FBXO7,YES1,CSTF3,SRPK2,VIRMA,CCNF,EIF4A3,EZH1,UBE2I |
| 6.822e-09 | -18.80 | RHOC (ras homolog family member C) | protein interactions | 389 | 575 | 224 | 19454 | 5460 |
CNP,RABL3,ARHGAP1,SEC22B,ADIPOR1,MET,LMNA,JUP,GOLGA5,STOM,SLC12A2,SPCS2,MTDH,TMEM209,BRIX1,IL1RAP,YKT6,B2M,SLC7A1,DEPDC1B,HMOX2,RACGAP1,RHOBTB3,EPHA2,LGALS8,GANAB,SLC11A2,VAMP3,CTNNA1,SH3BP4,FERMT2,GNAI2,SNX3,YES1,MTARC2,LBR,SLC29A1,CCDC47,ALPL,KRIT1,SNAP23,EMC2,STX8,RAB1A,NSDHL,DLG1,CTNND1,RIGI,RAB23,ATP1B1,DAG1,RELL1,TMEM199,LAMTOR2,EMC4,OSBPL8,SLC2A1,POR,ESYT1,C2CD2,CDCA3,PTPN1,SRPRA,HACD3,CAV1,NOTCH2,PGRMC1,DAAM1,VAPB,CXCR4,RTKN,EXD2,STX7,ATAD1,MRPL16,PKP4,SCFD1,SLC7A11,LMNB1,RHOB,FZD6,AP2M1,GPR89A,PRDX2,LRRC8A,SPCS1,FAF2,RPL29,LGR4,IFNGR1,RAF1,MACO1,EMC10,ITGB5,CYB5B,VAMP2,STIM1,EZH2,RPN1,PCDH17,CTSA,PRPSAP1,JAK1,SLC39A7,GOLGA7,FLOT1,RETREG1,EMC8,ACVR1B,WDR11,PRDX1,RAB32,PIK3R1,PPP3CA,GJA1,WDR6,PPIA,TMEM237,CDC42,SPTBN1,LEMD3,CSNK1G3,SDCBP,USE1,SSR1,ARFIP1,RAB9A,TMEM185B,LRP10,GORASP2,SLC25A1,RAB2A,ATP1A1,CISD1,RAP2C,QSER1,MACROH2A1,STX10,NECTIN2,ROCK1,HPF1,RALA,UBIAD1,ZMYM4,PREB,UGCG,GNAI3,TFRC,BMPR2,SLC16A1,STX18,ABCE1,SLC6A8,FKBP8,NEDD8,SRPRB,KPNA1,NUS1,SLITRK5,FLRT2,RAP1B,SLC39A10,STT3A,ITGA6,ALYREF,LMAN1,STX6,SLC38A2,TMPO,DNAJC1,VTI1B,ARL6IP5,FZR1,IL6ST,ZC3H14,PAFAH1B1,GOSR2,TMEM184B,PAK2,UBAC2,BMPR1A,GNB4,ITGAV,ABCC5,PACSIN3,EMC1,MLF2,SLC30A5,STX16,SLC38A1,SPCS3,LAMTOR1,RRAS2,FAM83B,MTG1,ESR2,APEX1,ATP6AP2,NDFIP1,TMEM59,TUBA1A,MFSD6,STBD1,TOP3B,PTRH2,EFNB1,GNA11,TMEM87A,SLC20A2,NUP42,ROCK2,YWHAG,OLR1,PPFIBP1,DDRGK1,DDX50,WWP2,PTDSS1,ARHGAP5,AGR2,STX5,LAPTM4A,VAMP7,RAB1B |
| 6.840e-09 | -18.80 | PSMB9 (proteasome 20S subunit beta 9) | protein interactions | 5698 | 89 | 51 | 19454 | 5460 |
GNB1,SRC,POLR2B,PSMB6,PSMD6,PSMD4,POLR2F,PSMC5,PSMA6,PSMG3,PSMD14,POMP,PSMD1,FBXO7,PSMA4,PSMB2,G3BP2,PSMC1,PSMA3,PSMG4,OSER1,PSMB7,PSMB3,DDIT4L,PSMC4,POLR2I,STX5,PSMB1,PSMB4,PSMB5,POLR2L,PSME2,GTF2B,USP15,CRYGA,PSMD7,PSMG2,PSMD3,PSMD12,PSMB10,PSMA2,PSMA5,PSMA1,PSME1,RNF181,PSMC3,POLR2G,POLR2C,POLR2D,PSMB9,RAF1 |
| 6.942e-09 | -18.79 | IQGAP1 (IQ motif containing GTPase activating protein 1) | protein interactions | 8826 | 536 | 211 | 19454 | 5460 |
HNRNPA1,PSMD3,MRPS26,AHSA1,LBX1,PSMD10,RHOG,USP46,TSG101,PHB1,PSMB4,DHX15,SRSF10,CCAR2,SPTAN1,LGR4,PPP2R1A,ACTN4,RAF1,CHMP4C,EZH2,TRIP4,FLOT1,TRIM37,RBBP7,CUL3,VMP1,HTRA2,BRCA1,RHOB,LMNB1,FYTTD1,RPS9,SNRPD1,SNRPD2,AP2M1,GGPS1,ACTB,MYH1,PPP1CB,MYL6,VPS18,CXCR4,PPP2R2C,HDAC6,EID1,TES,NAP1L5,CDK9,PRNP,ARF6,PPP1R18,DDX39A,FBP1,OTX2,ILF2,PPME1,MAGEA4,ACTR2,PPP1R12A,FAF1,RPS13,FBXO25,WASL,THRAP3,CAMK2G,USP14,PPP1CC,XPOT,NCKIPSD,LRP6,AP2A1,UBASH3B,UBE2I,TUBA1B,EIF4A3,CTTN,CCNF,VIRMA,UQCRQ,RHOJ,TMOD3,SIPA1L1,MYL12B,EEF1E1,RPS14,TMOD1,RPLP0,METTL14,PAK5,CDK1,ARPC2,SQSTM1,SIRT7,DVL2,RHOU,RPA3,SOD1,INPPL1,PIAS1,PIK3R2,RPL4,CTNNB1,YWHAG,YWHAH,WWP2,TNNC2,CBL,AGR2,CORO1C,RAB35,HSP90AB1,DYNC1I2,SUMO2,HNRNPL,ISG15,SOX2,TOP3B,RPL18,EFNB1,MYO1B,RUVBL2,PABPC1,S100B,RUVBL1,PSMA1,KRAS,PSMA2,HNRNPF,PSMD1,MYC,CREBBP,H1-1,CYP1A1,LAMTOR1,CCT2,CKB,DLST,LMBR1L,VDAC2,RABIF,PSMB6,PSMD6,MATR3,PSMB3,PIH1D1,MAP2K1,DDX5,HSPA8,SPECC1L,DDX39B,PACSIN3,SAP18,STAU1,TPM3,API5,USP15,SHC1,SNRNP70,RAC2,ADD1,ALYREF,SYNCRIP,SDHB,CDC5L,KCTD3,RAP1A,CDK4,TP53,NUPR1,ARPC3,CAPZA2,TFRC,CYBRD1,ABCE1,RPL3,MAP1B,PALM2AKAP2,HNRNPK,CSE1L,TGFBR2,PSMA5,CFL1,CFL2,ARHGAP21,AKT1,RAB2A,UBE2H,ATP1A1,ZBTB38,PDCD4,PSMC5,CSNK2B,MOB4,SRC,NMI,SMURF1,ADRM1,DAPK3,CFTR,CDC42,SPTBN1,HECTD1,UBE2M,TFIP11,STX17,RPA2,RNF113A,BAP1,HSPA5,WDR3 |
| 7.029e-09 | -18.77 | regulation of translation | biological process | GO:0006417 | 450 | 189 | 18204 | 5365 |
NGRN,MIR101-1,MIR24-1,POLDIP3,SHMT1,TNF,ETF1,CNOT6L,RPS3,EEF2,TNRC6C,HNRNPD,EIF4A3,MIR145,SH3BGRL,BOLL,RGS2,YTHDF1,MIR495,MIR205,SELENOT,MALSU1,MIR98,LARP4B,ELP3,DNAJC1,EIF5B,MAPKAPK5,USP16,IGF2BP1,LSM14A,DAP,PABPC1,TYMS,EIF2S1,MIR16-1,EIF4E2,FXR2,CYP1B1,TACO1,PAIP2B,MIR181D,MIR17,MIR214,MRPL13,GTDC1,MIR378A,CASC3,MIR133B,NCBP2,MIR135B,MIR15A,MIR1-1,PIWIL4,BZW2,PIWIL3,UQCC2,EIF1B,CNOT8,MIR26B,MIR939,ATF4,POLR2G,TCOF1,MIR148B,ENC1,MIR590,EIF3E,MIR298,MIR181C,MTPN,GAPDH,CNOT7,MIRLET7I,RNF139,MIR28,MPV17L2,MIR29A,EIF2B2,UPF3B,MIR874,PIWIL1,YTHDF2,EIF4H,IFRD2,MIR106A,SESN2,TRIM3,BTG2,IMPACT,MIR100,EIF3K,METTL14,EIF2B5,EIF4EBP3,MIR218-1,RBM3,MIR212,MIR503,EIF3D,MIR144,CALR,METAP1,MAGOH,MIR346,CNOT2,INPP5E,LSM14B,MIR877,MIR9-1,NCK1,MIR345,DHX9,AKT1,ELAVL4,MIR182,MIR1271,RPL26,EIF4B,ITGA2,RPS4X,ACO1,PIWIL2,MIR125A,PELO,MIR200C,EIF4EBP2,MIR29C,MIR448,ABCE1,DIO2,MIR10B,EIF2AK2,RPL13A,CIRBP,EIF4A2,CPEB1,CSNK2A1,MIR20A,PYM1,CNOT6,PAIP2,MIR221,EPHA4,RPS14,DDX1,MIR106B,CCL5,PAIP1,MIR107,DAPK1,AGO1,HSPB1,SECISBP2L,EIF4E,MIR379,MIR126,IL6,MIR132,UHMK1,EIF5A2,AKT2,DAPK3,KLHL25,MIR204,EIF4E3,MTG1,IREB2,RMND1,UCN,MIR210,RPS9,CD28,SYNCRIP,NGDN,MIR148A,MIR31,RPL10,METTL18,TIA1,ALKBH5,MIR208A,MIR21,MIR96,MTG2,RPS27L,DNAJC3,MIR146A,ELP6 |
| 7.218e-09 | -18.75 | RPUSD4 (RNA pseudouridine synthase D4) | protein interactions | 84881 | 246 | 111 | 19454 | 5460 |
MYC,PYCR1,TMED4,HNRNPC,MRPS25,MCAT,RIT1,TACO1,DLST,MRPL13,ATP5F1B,MRPL23,KBTBD6,NDUFAF4,NOTCH2,PRDX3,MRPL12,MRPS18A,NDUFA5,NGRN,NDUFS2,FTL,MRPS7,CLPX,STOML2,MRPS35,NDUFV2,MRPL9,MRPS26,PHB1,FAAP100,HNRNPL,NDUFS8,HSDL2,ETFB,NUDT19,NDUFS6,PDHA1,PNMA2,NDUFA12,HSPD1,PREPL,HINT2,COX8A,FHL3,ETFA,ATP5F1D,KGD4,NUP42,MRPS17,TMED7,HNRNPDL,NDUFAF2,PYCR2,MRPS16,MRPL53,EIF2AK2,MRPS28,ACAT1,ATG16L1,RBMS2,CCL3,MRPS34,QRSL1,MTRES1,CYC1,TWNK,DLAT,NME4,PDHB,MRPL17,MRPL41,MRPL40,GRPEL1,MRPL20,MOV10,GRSF1,KLHL22,MRPS9,SYNCRIP,MGME1,PRR3,MRPL50,ATP5PD,DBT,MALSU1,RBM42,MRPL24,MRPS23,HINFP,ATP5PB,NDUFA2,MRPL47,TP53,MRPL11,PPIF,METTL15,BCS1L,NDUFS3,MRPL49,MRPL51,ATP5PF,MRPS18B,HSD17B10,PDE12,CAMK2G,MRPS33,MRPS18C,MRPL22,FASTKD5,ABHD10 |
| 7.368e-09 | -18.73 | DKC1 (dyskerin pseudouridine synthase 1) | protein interactions | 1736 | 371 | 155 | 19454 | 5460 |
RC3H2,ELAVL2,MAPRE1,UBE2H,RPF2,SUB1,CIAO1,RPL7A,RPL26,DEPDC1B,RPL13A,SMURF1,SRPK2,BCCIP,UQCRC2,ZNF330,EIF2AK2,FGFBP1,PRKRA,WRAP53,RPA2,LMNA,MRPS34,LSM2,GRM2,SSR1,RPLP0,MACROH2A2,RBMS2,FGF13,DGCR8,EIF5B,FBXW7,RPL4,NHP2,UTP23,RPA3,NLE1,MTDH,SNRNP70,H2AC4,CHCHD1,MPHOSPH10,RPS2,KPNA1,NOL12,MOV10,GRSF1,RBM17,CSNK2A1,E4F1,RPS16,CAND1,DKC1,ZBTB2,SRP14,SYNCRIP,KRR1,PRR3,LLPH,CAMK1,RBM34,HBP1,NUPR1,RPSA,H2AX,RPL15,CAMKV,NOC4L,PTGES3,RPL17,TCOF1,ABCE1,RAB27A,RPL23A,RPL3,HSD17B10,FBXW11,ATG3,LMNB1,ZCRB1,DCAF4,FTSJ3,H1-1,CDKL2,RIT1,MYC,HNRNPC,SFN,CUL3,BTF3,SNRNP40,RPL35,APEX1,RPL10,RPL19,FAU,RSRC1,DLST,RPL37A,RPS9,LARP4B,PABPC5,H1-5,FGF17,NOP53,EEF1G,STAU1,COIL,LYPLA2,TERT,EP300,DDX23,TERC,HNRNPD,IFI16,XPO1,HNRNPA1,DDRGK1,RPS10,NOP58,MPP1,LYAR,RPL7,SRSF10,DHX15,RPL8,SRSF1,EED,CHMP4C,HDAC11,AAMP,RPL18,RAF1,TOP3B,H1-3,MAK16,PAIP2B,G3BP1,KRAS,H1-6,VDAC1,HMGN4,RUVBL1,SRSF4,RPL28,RPS4X,SSRP1,RPL31,PPAN,ARGLU1,RUVBL2,SRSF7,TRIM11,RPS24 |
| 7.424e-09 | -18.72 | GTPase activity | molecular function | GO:0003924 | 326 | 146 | 18094 | 5411 |
GNG10,MTG2,GFM1,NTPCR,ARF1,RAB3A,RAB32,GNAO1,RABL2B,RALA,RAB13,DIRAS2,TRIM23,ABCE1,RAB22A,RHOB,RAB33B,RGS2,RND2,RAP2A,RGS10,GNB3,RAB19,GNG11,RHOBTB3,HRAS,NKIRAS2,MTG1,MMUT,RHOG,SAR1B,ARL10,RAP2C,RHOH,GPN2,RAB9B,ARHGAP5,IFT22,ARL5B,MX1,GNA11,RAB5A,RASL12,RAC2,RHOJ,RALB,RAB39B,RAB29,RAB23,DNM2,TUBB,RAB11B,GNGT2,GNAQ,DIRAS1,ARL4A,RIT1,AGAP2,RAP1A,ERAS,CDC42,RERG,DRG2,RAB1A,RHEB,GNA14,RAB30,SEPTIN7,RAB3D,RAB18,RASD1,TUBB4B,AGAP1,RGS6,GFM2,RAB4A,GNL1,RGS5,MMAA,GNAZ,GNG5,RAB35,DIRAS3,RAB37,RRAGB,RAB3B,RAB9A,RAB31,MRAS,GNG3,SRP54,EEF1A1,RIT2,ARL11,ARL6,SEPTIN6,ARL4D,RHOBTB1,RAP2B,EEF2,ENTPD4,RABL3,RAP1B,GTPBP1,EIF5B,KRAS,ARF6,RGS1,RAB6A,RASL10B,DNAJC27,ARL15,DRG1,GNAI3,RND3,SRPRA,RAB8B,RAB33A,GNB1,TUBA1B,ATL1,RASL11A,MX2,RRAGA,RAB2A,RAB40AL,RAB6B,GTPBP2,RASL10A,TPPP,RAB27A,NKIRAS1,TUFM,RAB11A,RAB28,RAB3C,MFN1,RHOU,GNAI2,ARF4,RAN,RAB1B,RAB5C,RAB14,RRAS2,RGS19 |
| 7.674e-09 | -18.69 | WWOX (WW domain containing oxidoreductase) | protein interactions | 51741 | 612 | 236 | 19454 | 5460 |
CPSF1,ARF1,SNRPD1,SNRPD2,UMPS,PRRC2A,PRPF31,OTUD7B,SAMHD1,SMARCE1,YWHAZ,BRCA1,WBP2,HSDL1,HADHA,RADX,CYFIP2,PSMC1,PXMP2,COIL,PGRMC1,WDR77,TIMM13,MYH1,FEM1A,USP39,IFIT2,TSG101,GJA1,ATXN10,AGK,DHX15,CACYBP,ERLIN1,SRSF10,STOML2,MARCHF5,PDIA3,PLAC8,ATG9A,DROSHA,LYZ,AHSA1,TMT1A,BAG2,PCNA,LASP1,RFC2,ENKD1,ERLIN2,GFPT1,FAF2,RPN1,JPT2,POLR2C,EIF4A3,ENO1,STUB1,UFSP1,ZMAT5,GANAB,NDN,TECR,UBB,NONO,ATOSB,GGCX,XPOT,FAM222B,DVL2,INPPL1,RAB33B,PDHB,SEC22B,SF3A1,CNP,CDK7,GABARAPL2,JUP,P3H1,CTDSP1,LMNA,CDK1,PAX9,HNRNPH3,RARS1,SPMIP9,HACD3,SRPRA,H2AZ1,SMAD3,PTPN1,AIFM1,SEC23A,HSD17B11,CAV1,SLC25A12,MDM2,SLC25A46,LAMP3,ESYT1,NME2,STYK1,DNAJC7,SFXN1,HSD17B10,WASL,TTC4,THRAP3,FARSA,LSM4,HUWE1,ANAPC11,MSH6,ARF4,YTHDF2,LBR,NDUFS3,POLR2G,VDAC2,PHF21A,PRMT5,MATR3,PPP5C,POLR2B,CPSF2,PSMD1,LAMTOR1,CCT2,THOC6,SLC15A2,ACTMAP,RFC4,DDX39B,RAMAC,LCN1,ARRDC3,HSPA8,SF3B1,SSR3,USP6NL,LMO3,SEC62,FRS3,FDFT1,RPRD1A,SNRPD3,AASDHPPT,HNRNPL,CCT7,RPL6,RAB5C,LAMP2,IQSEC1,XPO1,SHC3,PPIB,DRG1,HSPB1,DDX1,PABPC1,CYP2C9,BCL9,RPAP3,LDLRAD4,HNRNPF,TFG,DCTPP1,KIF2A,PDHA1,RAB4A,TUBB4B,SERPINA5,RND3,ZBTB33,CDIPT,SF3B6,PSMC5,SEC61A1,CSNK2B,DHRS13,HPF1,SRC,MYG1,CSTF3,SLC25A1,LACRT,ATP1A1,IGF2BP1,RAB9A,DLAT,HSPB2,RBM22,KDM1A,LITAF,MARS1,HYAL2,NTPCR,SSR1,RPRD1B,LUC7L3,COMT,SDHB,STT3A,GNPAT,PLSCR3,CAND1,CDC5L,LMAN1,DKC1,CSNK2A1,SMAD4,SLC25A11,DDR1,NOSIP,DHX9,ABCE1,SLC16A1,RAB13,LRP3,SRPRB,HNRNPK,TMEM33,CAPZA1,FKBP8,MTCH2,TP53,ATP5PB,PREB,ZNF581,ESS2,ACADSB,IK,SURF4,TFRC,PSMC3 |
| 7.697e-09 | -18.68 | SCO1 (synthesis of cytochrome C oxidase 1) | protein interactions | 6341 | 165 | 81 | 19454 | 5460 |
TOMM70,COX14,MRPS23,SLC25A12,PLGRKT,SYNCRIP,TIMM8B,AIFM1,COX4I1,CDCA3,RHOG,AK2,SMIM12,TMEM70,MED4,HAX1,CLPX,CIDEB,COX5A,MTMR12,WDR19,AKAP12,KGD4,ETFA,SFXN1,NDUFA4,ATP5PF,CLPB,OPA3,FHL3,COX19,NDUFS3,NDUFS6,FAM136A,ATP5PB,SNAP29,ETFB,APOO,TIMM8A,MTM1,CHCHD3,PARL,UQCRC2,CCDC90B,CHCHD6,KIAA1191,COX16,CHCHD4,NRP1,NTRK3,RIT1,UBE2H,COX6B1,PYCR1,PYCR2,COX11,NDUFS2,SLC25A51,TOMM20,RPA3,COX17,CMC4,MAVS,SQSTM1,TMEM126B,AKAP1,MED23,ATP5PO,RPA2,LMNA,SAMM50,NDUFA5,CAV2,TIMM10,TOMM22,GTF2H4,TIMMDC1,MTX2,TIMM13,UQCRC1,CDC42 |
| 7.697e-09 | -18.68 | DNAJC15 (DnaJ heat shock protein family (Hsp40) member C15) | protein interactions | 29103 | 165 | 81 | 19454 | 5460 |
CLPX,GRSF1,STOML2,MRPS35,RPL6,NDUFV2,MRPL9,MRPS26,HAX1,DICER1,SDHB,RPL8,MRPS9,PHB1,COX4I1,RPLP2,MRPL50,RPL7,PNPLA8,NDUFS8,MRPS23,MRPL24,NDUFA2,MRPL47,BCS1L,RPL15,NDUFS6,NDUFS3,NDUFA12,RPL18,MRPL49,RPL3,MRPS18B,SLC16A1,HSD17B10,DHX9,PDE12,KGD4,ETFA,MRPS17,MRPL22,ANP32B,RPL17,NDUFAF2,NDUFB10,RPL7A,PYCR2,PYCR1,MRPS25,TACO1,DLST,LRRC1,MRPS28,RPS12,PTPMT1,MRPL13,MRPL23,SIAH1,RPL13A,NDUFAF4,TIMMDC1,MRPL12,NDUFAF3,MRPS34,VAPB,RPLP0,NDUFA5,RPL27,PPM1G,HADHA,DLAT,NME4,MRPL17,TIMM17A,NDUFS2,PHB2,MRPL41,RPL4,MRPS7,CMAS,MRPL20 |
| 7.749e-09 | -18.68 | MRPL2 (mitochondrial ribosomal protein L2) | protein interactions | 51069 | 216 | 100 | 19454 | 5460 |
RPL13A,MRPS21,MRPL53,MRPS16,UBE2H,TUFM,RPL26,MRPL41,MRPL40,MRPL17,RPS15,MRPL20,GFM1,ZNF326,MRPS34,MTRES1,RPL26L1,TFB1M,RBMS2,KLF12,MRPL10,NDUFAB1,MRPL50,MRPL24,DKC1,MALSU1,KRR1,MRPS9,TMEM70,SNRNP70,GRSF1,MOV10,MRPS33,RPL17,MRPS18C,MEPCE,MRPL22,SRSF12,MRPL52,RPL23A,MRPL49,MRPL51,MRPL33,GFM2,MRPL47,MRPL11,METTL15,EXOSC8,APOBEC3D,RPL35,MRPL23,RPL19,RPL10,ESR2,CCDC90B,MTG1,DLST,TACO1,RPS9,MRPL13,CDC7,FTSJ3,ZCRB1,MRPS25,NSA2,CUL3,PMPCA,AUH,MTG2,MYC,MRPL16,MRPL57,PHB2,HSCB,FTL,MRPS7,NGRN,RAB5A,MRPL34,MRPS18A,SLC25A3,KLHL3,RPL27A,MRPL12,RPS10,HP1BP3,GATD3,FAHD1,MRPL18,RHOG,MRPS26,MRPS35,MTRF1,MRPL9,MRPS17,MRPS11,HINT2,PDHA1,EZH2,SOX2 |
| 7.755e-09 | -18.67 | EIF6 (eukaryotic translation initiation factor 6) | protein interactions | 3692 | 351 | 148 | 19454 | 5460 |
PIH1D1,PRDX3,NOP53,PAFAH1B2,STAU1,UFL1,TRA2B,GINS3,POLA2,UPF3B,PEBP1,EP300,TXNL1,BRCA1,LMNB1,ATG3,CCT2,RIT1,TNFAIP8,RPS5,PFDN4,CUL3,PSMA4,ACO2,MYC,GGH,PSMD1,POLR2B,LRIF1,PPP5C,RAN,RPL37A,BZW2,CHMP4C,PDHA1,CRELD1,E2F4,RAF1,ANP32A,TOP3B,NUDCD3,SOX2,ETFA,KRAS,RPS4X,TOP2B,CCT8,ABCF1,PPAN,RPL31,RPS24,RUVBL2,FKBP4,AGR2,SKIC8,DICER1,RPL23,YWHAB,HNRNPD,RPL6,WWP2,IFI16,CNOT2,CTNNB1,DDRGK1,PPIB,ATG7,TCP1,SUMO2,RPL7,NOP58,OS9,NUP35,PHB1,RPL8,RPL9,GATD3,RPLP2,ARHGAP25,RPLP0,RARS1,CAPN1,ATG16L1,SPTBN1,CDK7,EIF3J,RPL4,EIF5B,BRIX1,EIF4E,ZC3H15,SIRT7,BAP1,RPL27,RNF113A,PRKCB,RC3H2,UBE2H,PDCD4,OAT,RPL7A,PPP1CC,DNAJC8,CFL1,RPL13A,ZNF622,HPF1,BCCIP,EIF2AK2,CCNF,STUB1,PTEN,CSNK2B,DNAJC2,RBM34,RNF8,NUPR1,MSRB3,VAC14,ZBTB26,CCT5,DDX39A,MAP2K3,RPL17,PSME1,SNIP1,DHX9,SOS2,RPL3,H2AC4,SNRNP70,RPL10A,TSNAX,PGAM1,MOV10,API5,CSNK2A1,RGS10,CAND1,FZR1,ARF6,KLF9,ZBTB2,RBM42,FUNDC2,DFFA,RPL12,NLRP1 |
| 7.769e-09 | -18.67 | DUSP22 (dual specificity phosphatase 22) | protein interactions | 56940 | 139 | 71 | 19454 | 5460 |
RAB5A,RAB9A,GNA14,SPECC1L,UNC45A,TMUB1,TIMM17A,DUSP22,PGRMC1,ARHGAP1,SEC22B,RPL27A,CSNK1G3,SAMM50,CDK1,PTP4A2,GNAO1,GANAB,RMDN3,SRP54,SYNGR1,ARF1,FAM177A1,VAMP3,CHP1,GNAI2,USP5,CHCHD3,YES1,TAGLN2,RAB14,HMOX2,MCM4,STX16,FBXO7,TOMM40,LAMTOR1,SNAP23,TMX3,GNG5,CLPB,CCNY,ABCE1,GNA11,ARF4,MCM6,KRAS,HPCAL1,MTCH2,RAP1A,DCAKD,GNAQ,CYB5B,GNAI3,PTRH2,NME1,CTNNA2,NRN1,MCL1,EIF4E2,HRAS,SRPRA,UBTD2,SVIP,ATXN10,VTI1B,RAB5C,HAX1,MOSPD1,TMEM70,TMEM11 |
| 7.805e-09 | -18.67 | Thioredoxin-like_sf | interpro domains | IPR036249 | 127 | 68 | 18521 | 5414 |
SH3BGRL,GPX4,GSTO2,TMX3,TMX4,MIEN1,FAXC,GPX6,TXNDC17,TXNL1,PDCL,GDAP1L1,GSTM5,GSTT1,MRPS25,GSTO1,GSTA2,DIO2,TXNDC12,GSTM2,PRDX6,SELENOF,SELENOW,PDIA6,NDUFV2,SELENOV,TXNRD1,GRXCR1,PRDX4,GPX7,SELENOM,ERP29,PDIA3,TXN,GPX1,TMX2,GSTK1,PRDX2,GSTA4,FAF1,GSTA1,GPX5,DIO1,TUSC3,NDUFA2,TXNRD3,GLRX2,GSTT2B,GPX3,FAF2,PRDX3,TXNL4A,DNAJC10,PDIA2,EEF1G,GSTM3,GSTP1,AGR2,HPGDS,SELENOT,GLRX,CLIC4,PRDX1,GLRX5,GPX2,GSTM4,DIO3,CLIC2 |
| 7.871e-09 | -18.66 | EIF3G (eukaryotic translation initiation factor 3 subunit G) | protein interactions | 8666 | 227 | 104 | 19454 | 5460 |
RPL32,AIFM1,PRNP,RPS16,FZR1,RBM42,USP3,ENY2,CD81,CSNK2A1,COPS5,RPS2,DHX9,ABCE1,EIF4EBP2,SMN1,EIF3E,RIGI,RPS13,TP53,NFE2L2,DNAJC2,SRP72,CAPN2,METAP2,CCNF,PSPC1,RPS3,RPS20,EIF2S2,NREP,TXN,VIRMA,RPL22,RUNX1,RC3H2,BICD2,EIF3G,UBE2H,PDCD4,PML,RPA3,BAP1,RTN4,LSM12,RPL4,RPS15,EIF4E,CFTR,EIF3J,RPA2,LMNA,DYRK2,HEXIM1,UBE2M,DYNC1I2,PAIP1,EIF2S1,WWP2,EIF3D,DDRGK1,DRG1,MPHOSPH6,AHSA1,TRIP4,RUVBL2,KRAS,G3BP1,EIF2D,RPS4X,RPS7,PRKAG1,EZH2,RPS23,RPS11,EIF3K,PELO,CMTR1,TENT5C,EIF4A2,ESR2,PRRC2A,RPL10,GADD45G,CUL3,SFN,RAB11A,MYC,BRCA1,ICAM1,RPS26,RPS5,HTR1A,EP300,RAB5A,EEF1G,UFL1,EIF1B,G3BP2,EMC9,PALS2,PIH1D1,EIF4B,NUFIP2 |
| 7.878e-09 | -18.66 | PCNA (proliferating cell nuclear antigen) | protein interactions | 5111 | 477 | 191 | 19454 | 5460 |
MYC,CREBBP,SNRPB,H2AZ2,MRPS25,GADD45B,RBBP8,APEX2,SMU1,APEX1,GADD45G,NEK7,TIRAP,SEC22A,MAP2K1,ADSS2,PLAA,XRCC5,RFC4,EP300,HSPA8,HDAC5,UFL1,UBE2D3,PACSIN3,WWP2,LAMP2,BAZ1B,SIVA1,CTNNB1,DDRGK1,PPIB,MGMT,HEXA,ERRFI1,SPG21,MOB3C,RUVBL2,CDK5,EWSR1,XPNPEP1,KRAS,DCTPP1,CCAR1,CCNB1,SUB1,TRIM23,SPOP,UBE2H,RBM7,CALU,DTL,ZBTB38,SGTA,ING2,CDC20,SUMO1,AKR7A2,CFTR,RPA2,HEXIM1,UBE2M,PML,POLD2,BAP1,RNF113A,PRDX6,TNFAIP1,PGK1,PGAM1,USP2,GAPDH,NOS1AP,POLB,CDK6,MCL1,SHPRH,SPPL3,FZR1,TP53,RPSA,CDK4,RNF8,NUPR1,DHX9,TOLLIP,KPNA2,NEDD8,H3C1,CUL3,CUL2,DSN1,MCM4,RFC5,MAP3K21,BRCA1,FAS,SENP8,RIT1,POLD4,AP2M1,USP5,ASB8,CDKN1A,PRDX3,PCLAF,USP39,DNAJC3,NMRAL1,CMTM6,HSCB,MLH3,CCND3,POLA2,BABAM1,PSMD10,PDCD10,PHB1,KCTD10,DHX15,NUP35,PPIA,EGLN3,RAF1,B3GNT2,FEN1,EZH2,GADD45A,DNTT,PCNA,TRIM37,TRIM26,G3BP1,RFC3,SSRP1,RFC2,RAD21,SAR1B,UBE2A,PPP1CC,NONO,TXNIP,HERC4,CA2,CDC73,ENO1,TUBA1B,CCNF,UBE2I,PTEN,GNPDA1,LDHA,VIRMA,UBB,CCND1,UBA52,ELP3,CCNA2,CDK7,HSP90B1,LMNA,CDK1,KRT7,MME,RPA3,PRIM2,KIN,DGCR8,POLDIP2,PIAS1,EMC4,CALR,HDAC6,ARL10,TOP1,MDM2,POLE3,ING1,EEF1A1,UBE2B,DMAP1,PPME1,TCOF1,IGF1R,LIPA,B4GALT7,POLL,CCL2,HUWE1,MSH6,RNF20 |
| 8.038e-09 | -18.64 | FAF2 (Fas associated factor family member 2) | protein interactions | 23197 | 421 | 172 | 19454 | 5460 |
MYC,UFD1,PSMD14,SERPINH1,FIS1,LMBR1L,VDAC2,ATP5F1B,ESR2,TOMM22,SEC62,YIPF5,UBAC2,EP300,AKAP1,HSPA8,TRA2B,EMC1,NDUFS2,UFL1,RAB5C,LAMP2,DDRGK1,AGR2,ARL14EP,PEX3,RAB35,TUBA1A,RAB4A,MOB3C,CYP2C9,KRAS,RAB2A,TRIM23,SPOP,CALU,UBE2H,CDKN2AIP,OAT,ATP1A1,UQCRC2,SMURF1,SUCLG2,CFTR,CDC42,TRAM1,SSR1,RPA2,PSEN2,RAB9A,DERL1,HSPA5,PIP4P1,TOMM20,ADIPOR2,EDEM1,SELENOS,ELOC,ZFAND2B,TUBG1,COX4I1,CD274,STT3A,RAC2,CAND1,DNAJC1,TMED9,FUNDC2,TMPO,ILVBL,LMAN1,MTCH2,INSIG2,UBL4A,ACADSB,TMEM31,GPD2,SLC25A24,MAP1B,CSE1L,RAB3B,FKBP8,CUL2,RAB11A,CUL3,USP13,TOMM40,LMNB1,FAS,VMP1,SEC61B,RMDN3,TIMM29,RND2,OTULINL,VAPB,EXD2,ATP2C1,ATAD1,HSCB,UNC45A,COIL,PXMP2,FBXL4,MARCHF5,PTPN5,ATG9A,UBXN6,RHOG,UBE2D1,VCPIP1,RB1CC1,FBXO32,KRT8,GJA1,OS9,ERLIN1,EGLN3,ERLIN2,FAF2,RPN1,STIM1,RNF126,TMT1A,UBE3A,S100A10,TRIM37,G3BP1,RNF26,SAR1B,IMMP2L,AR,TUBA1B,ENO1,CCNF,SLC25A4,YES1,VIRMA,UQCRQ,UBB,TIMMDC1,ST7,STOM,HSP90B1,GRM2,TIMM23,HAUS2,RPA3,MAVS,SYVN1,FBXW7,TMUB1,SLC25A46,MFN1,LAMP3,ESYT1,ARL10,HACD3,PTPN1,AIFM1,HSD17B11,DERL2,ARF6,ANKRD46,CAV1,SLC25A10,FAF1,EMC2,HUWE1,MSH6,RIGI,PSEN1 |
| 8.067e-09 | -18.64 | response to decreased oxygen levels | biological process | GO:0036293 | 306 | 137 | 18204 | 5365 |
CYP1A1,PICK1,BECN1,SLC29A1,DPP4,CLDN3,HP1BP3,NDP,CBL,TLR2,ERO1A,TERC,MIR20A,MIR214,CPEB1,MIR17,CD38,MIR448,BAD,EGLN2,PRKCE,ADO,TERT,MAP1LC3A,KCNJ8,FOSL2,LTA,GAD2,HSP90B1,PML,FOS,NPPC,NGB,ITGA2,SMAD4,AGER,CREBBP,FUNDC1,DDIT4,CXCR4,NKX3-1,NDNF,TGFB3,KCNMA1,KCND2,CXCL12,AIFM1,AKT1,WDR83,NOP53,SOX2,STUB1,LMNA,HILPDA,BIRC2,TFRC,OXTR,EGLN3,MT3,KCNMB1,AGTRAP,SLC1A1,PARP2,IL1A,TGFB2,SMAD3,TNF,ADIPOQ,SLC2A1,UCP2,DIO3,STC1,EP300,MIR146A,CCNA2,PPARG,SCFD1,CAPN2,FZD4,PGK1,AQP3,ALKBH5,RGCC,SUV39H1,CDKN1B,CHRNA7,CHRNB2,CAV3,MSTN,BNIP3L,VEGFA,MIR210,PMAIP1,EDNRA,MECP2,EGR1,NFE2L2,EPO,SLC6A4,CAV1,NR4A2,RAD21,VEGFC,LEP,PPARA,HMOX2,MIR140,TM9SF4,ATF4,CLCA1,PSEN2,PHB2,SOD3,CIAO3,SRC,ADORA1,FAM162A,COMT,KCNJ11,MGARP,CRYAB,MIEF1,ACAA2,SOD2,MIR34A,SFRP1,MIR126,MYC,CYGB,TP53,MMP14,ERCC3,MDM2,F7,MIR223,SLC2A8,MIR106B |
| 8.434e-09 | -18.59 | POLR3A (RNA polymerase III subunit A) | protein interactions | 11128 | 160 | 79 | 19454 | 5460 |
UBN1,LURAP1,POLR3B,POLR2F,POLR3H,POLR2B,VIRMA,SMARCA5,MYC,CIAO1,TUFM,PPP1CC,PCBD1,ATG3,PFDN2,RPS5,RIT1,POLR1B,PFDN6,MAF1,RPA3,SNAPC1,HIRA,EXOSC4,MRPL17,PPP2R2C,STAU1,TRIM52,POLR1H,FTL,MRPS7,H1-5,MYL12B,POLR1D,NEK7,RPA2,RPRD1B,VPS18,HECTD1,PIH1D1,RPRD1A,GTF2B,POLR2L,CAMLG,POLR3F,POLR2I,EGLN3,MRPL24,PSMD3,CSNK2A1,POLR3GL,HAX1,ASB7,BRD3,PSME1,RPAP3,RUVBL2,EWSR1,TESK2,KRAS,RUVBL1,DNAAF10,ASF1A,PSMD12,PDRG1,MRPL22,GTF3C3,RIGI,PTGES3,TRMT1L,MRPL11,RPAP2,PPP2R1A,VPS33A,POLR2C,POLR2G,SMARCB1,CAPN2,POLR2D |
| 8.467e-09 | -18.59 | GOLT1B (golgi transport 1B) | protein interactions | 51026 | 230 | 105 | 19454 | 5460 |
INPP5K,UQCRC2,CHCHD6,MGST3,UQCRQ,VIRMA,ATP5F1A,ENDOD1,NAPA,ATP1A1,ABCG2,CALU,RPA3,PML,LRP10,SPCS2,RTN4,CHMP2B,PIP4P1,TMUB1,RABL3,SEC22B,UQCRC1,CDC42,LMNA,SDCBP,RPA2,JUP,USE1,STOM,CHMP1A,CHPF2,CYC1,NDUFB4,COX4I1,HTRA1,EXTL2,FUNDC2,SLC38A2,PLGRKT,CAV1,TMEM199,COX5A,ESYT1,OSBPL8,ATP6V1D,ATP5PF,BSCL2,PTGES,CYBRD1,EMC2,TMEM33,PDE2A,SFT2D2,RDH11,NDUFA2,LBR,DDX39A,TFRC,NDUFS3,DHRS7B,VDAC2,ATP5F1B,REEP4,CHCHD3,NDUFB7,BTF3,SCFD1,ATP2C1,CXCR4,RABAC1,NDUFS2,PHB2,ATP6V1G1,YIPF5,CD59,VAPB,ATP5PO,UBAC2,FAM8A1,NDUFA5,NABP1,PHB1,ATP6V1A,NDUFS8,ERLIN1,RAB11B,TMEM237,PDIA3,RAB5C,STOML2,NDUFV2,SKIC8,NDUFB8,RINT1,VDAC1,FLOT1,ETFB,PPP2R1A,SPG21,ERLIN2,NDUFS6,CRELD1,NDUFA12,HGS |
| 8.471e-09 | -18.59 | regulation of proteolysis | biological process | GO:0030162 | 603 | 242 | 18204 | 5365 |
PARL,BAD,SUMO1,RGMA,GSK3A,PSMA3,CDK5RAP3,TSPAN15,MIR339,NR1H2,USP14,MIR29C,JAK2,PTEN,BCL2L1,HSPE1,IGBP1,MIRLET7B,FIS1,ATP5IF1,PAK2,CSTB,PSMC3,CSTA,CAAP1,ANP32B,FAS,TMEM168,CSNK2A1,SNX12,RGN,TSPAN5,IL1R2,GPX1,CYFIP2,CTSK,BAK1,PACSIN3,BOK,NEDD8,ZFAND2A,DPEP1,APH1A,SVIP,TANK,KHDC1,MIR152,SNX33,GABARAP,IL1B,SIAH2,NOP53,TNFSF15,SPOCK1,AKT1,SERPIND1,AIFM1,TM4SF20,SOX2,USP13,GCLC,CAV3,USP5,HSP90AB1,PMAIP1,CDKN2D,WNT10B,FURIN,SERPINB9,BCL2A1,CAV1,RPS27L,MTM1,ARL6IP5,PSEN1,DNAJB2,MIR21,SFN,DNAJB6,AQP11,MCL1,SERPINB10,SERPINB6,TSPAN17,RHOBTB3,IFT57,SOCS5,SMURF1,SPOP,RUNX1,HTRA2,TNFRSF1B,OPHN1,CAMLG,UBB,NUPR1,CDC20,FZR1,MMP9,DAPK1,MIR126,SERPINA1,CSNK1E,BAX,ZER1,RCHY1,MYC,TIMP3,USP38,MMP14,UBE3A,UBE2K,EPHA4,ACVR1C,SPON1,EFNA3,CST3,TRAF7,SERPINA5,RNF34,PRNP,SOCS4,RFX4,AURKAIP1,ENO1,BCL10,HSPD1,PDCD5,NLRP2,DAP,FBXW11,PIH1D1,CRADD,PML,DNAJC1,PSMC5,DISC1,SEMG2,PSMD10,PRSS37,PSMD14,TRIB1,CTSD,F2,PIAS1,CLDN3,PSME1,RAD23B,NLRP3,MIR17,RPS3,PSMC4,EGLN3,BIRC2,LAMP3,SERPINB1,TAF9,TRIM32,MUL1,ROCK2,IL10,SMAD3,RAF1,MIR24-1,XPO1,VSIR,TNF,DDRGK1,CCAR2,PYCARD,AGER,HDAC6,S100A10,RPS7,S100A8,NKX3-1,FBXW7,CDK5,HFE,CLDN4,STUB1,NLRP1,HMGB1,PSMC1,MIR205,SYK,PITHD1,CLU,TIMP1,VEGFA,FBXO22,NCSTN,PSMB9,TGFB1I1,GAPDH,PRELID1,NFE2L2,PRMT6,RNF139,CLN8,DET1,SERPINA3,SGTA,RPL23,CCDC22,PSME2,CSNK1A1,PPARG,IFI16,UFL1,DESI1,SUFU,PRKACB,COP1,HECTD1,GABARAPL2,PLGRKT,MIR15A,FHIT,CLEC7A,SERPINB11,ROCK1,CTSC,IFNG,TP53,SVBP,SPOPL,MDM2,TNFSF10,IFT52,FASLG,IFI6,KLF4,HSPA8,SERPINH1,SUMO2,SRC,BAG2,PSENEN,FAM162A,TIMP4,SERPINI1 |
| 8.732e-09 | -18.56 | MTCH1 (mitochondrial carrier 1) | protein interactions | 23787 | 192 | 91 | 19454 | 5460 |
PDCL,FGFR1,PSMC4,TIMMDC1,BNIP3L,YKT6,MAVS,ATP1A1,ATP1B3,CISD1,SYP,DEPDC1B,ATP5F1A,ST13,C9orf72,FGFR1OP2,GSK3A,STUB1,PSMC3,CLEC2B,ATP5PB,SNAP29,PSEN1,FKBP8,RAB3B,RAB1A,DNAJC7,NME2,PSMD7,ESYT1,SMIM12,TPM3,ATP1B1,MFN1,SLC25A46,EDEM1,ATP5MG,TOMM70,FUNDC2,ILVBL,PTPN1,ACSL4,EHBP1,SLC25A3,ATP5PO,ARMCX3,DUSP22,TOMM22,TOR1AIP2,MTX2,PSMC1,GNB4,FBXL4,UFL1,NDUFS2,HSCB,TXNL1,AKAP1,HSDL1,EXD2,NLRP3,PSMD14,TOMM40,SCN3B,APLNR,CHCHD3,LAMTOR3,RMDN3,LMBR1L,VDAC2,CYB5R3,CYB5B,RPN1,FAF2,NUDCD3,MIEF1,SAR1B,USP30,TRIM26,VDAC1,ATP5F1D,EWSR1,ARGLU1,CDC23,FKBP4,DDRGK1,PSMD3,PRPF19,EGLN3,CACYBP,PRKCQ |
| 8.834e-09 | -18.54 | cellular biosynthetic process | biological process | GO:0044249 | 3776 | 1255 | 18204 | 5365 |
HNRNPA0,CPEB1,EXOSC4,CSNK2A1,RGN,RPL7,SUB1,CPSF4,NSA2,DHRS7B,IL1R2,SART3,ALG11,SOX9,MRPS17,ERO1A,PPIG,PDF,BAG3,POLA2,DICER1,IMP4,GXYLT1,BECN1,TOPORS,CWC15,RBM23,CHST11,MVD,SF3B5,DNAJC25,QTRT2,MTRF1,CYP1A1,LSM8,EIF4EBP2,TSN,BUD23,FKBP1A,NHP2,XXYLT1,PELO,GAD2,PRPF19,DHX15,CDC5L,CCS,SLC19A3,HSPA14,DRG1,CTU1,COL3A1,FKBP2,CHRAC1,DBR1,PLA2G15,RPP25L,DHX9,SDF2L1,SEPHS1,AMACR,MAT2A,STAT6,RNF8,CCR6,SF3A1,GALNT4,THOC3,DDX4,ZNF345,ADRB2,SRSF7,ZNHIT6,PRDM4,GFM1,CHST9,ST6GALNAC3,OSBP,GTF2B,AANAT,SUGP1,LTB,ZMAT2,TRMT5,LSM2,RPRD1B,PGAP2,EIF2B3,SMNDC1,LTO1,RPL29,LIAS,HYCC1,PAAF1,CDC37L1,HSPA5,SOCS5,KLHL3,HTRA2,THAP1,TAF5L,MYD88,GTF2H4,RPL10L,MRPL57,FAM98A,FXN,LSM10,DGCR8,RPL37A,CYP4F22,ALG5,EEF1E1,FASTKD5,THG1L,TRMO,GPBP1L1,RPL17,RPL18,SNRNP48,FURIN,F9,MRPS16,CMA1,SWAP70,RPS9,RUVBL2,YAE1,NXT1,MIF,PMM2,PCSK2,EIF5A2,REN,UST,TSSC4,BARX2,GTF2F2,OSGEP,SRSF12,SREK1IP1,TUSC3,ZDHHC15,PELP1,GBE1,HACD2,TLR3,DDX42,RPS14,MMUT,RTRAF,ARMC7,IFT172,RCHY1,MTMR6,SOCS2,AGO1,CRYAB,PGAP3,SECISBP2L,PPIA,GALNT12,H2AB1,PDHA1,CHST2,RP2,CEBPG,RBM38,SNRPD1,BOLA3,CNTN1,NLRP3,GTF3C3,FUT8,MFAP1,NHEJ1,ABCF1,ALDH1A3,CASC3,CHST7,MED4,LSM3,SUPT5H,NFYA,RBM5,CDK9,MPST,PRPF18,TAFAZZIN,CASP4,RPL6,ELOVL1,PTPMT1,RB1,IK,CYP11B1,GGT7,CD2BP2,TYMS,RSRC1,DNAJC10,SSU72,STUB1,ORMDL3,CERK,RPL28,RSL24D1,PFDN5,PLAC8,BCL6,PCLAF,MRPL34,ABHD5,HINFP,MED11,GTF2A2,CCT8,GRPEL2,SHMT1,TNF,CYP11B2,SF3B1,PPT1,TEX12,PHB1,PDIA3,PDE12,CDO1,TRA2A,BPNT2,ALG2,PPWD1,SNRNP40,FYTTD1,MRPL10,B4GALT3,DDX46,GSTA1,NAA35,SUV39H1,MLF1,RBM3,RBM15B,TRMT61A,GMPPB,RPL15,PAPSS2,METAP2,HMCES,WDR6,CDC123,LGALS3,GAPT,CYP27B1,B2M,ZNF326,PIWIL1,RPS26,GTF2I,TCEA2,DROSHA,PRIM2,EIF2B2,SAP18,ZNF473,TRIP4,EMG1,RPL9,GEMIN7,ITGAV,ZNHIT3,CHORDC1,HSPA8,PPIB,BAG2,INTS10,LARGE1,SCD5,IP6K1,RBMX2,TOR1B,INPP4A,SPTSSB,B3GALT1,ST3GAL4,KLF4,USP39,MRPS11,IMP3,RPS15,TLR4,RARS1,POLR1H,TMEM165,FADS2,TRMT13,ACCS,HENMT1,DDX23,PIGC,UBIAD1,SPCS3,MAEL,TP53,ST6GAL1,CIAO1,EPOP,FTSJ1,RPL35,ZC3H7A,CSGALNACT1,DDX5,NCBP2,SOD2,PFDN4,CPE,EIF4A2,TERC,DOLK,COQ8A,XBP1,TSPAN5,PNPO,RPL13A,RPL27,IL2,MSH6,CYTL1,PAIP2,HIRA,SNAPC5,AR,MRPL52,SOD1,TAF11,PPP5C,RPL4,PIP5K1A,PLA2G5,FTSJ3,PCSK9,NR1H2,B4GALT1,GLCE,DOHH,ACER3,B3GALT2,SRFBP1,SLC25A10,RPRD1A,PARL,DIO2,SMU1,CLP1,ELAVL4,CEBPE,KBTBD2,IL1B,BMP1,AKT1,FUBP3,UBA52,EXOSC8,RPS4X,HACD4,MTERF2,METTL15,FKRP,SLAMF9,EIF4B,CCT7,PDRG1,DNAJC24,RPL26,SGMS1,MRPL23,WTAP,ENY2,DKC1,APH1A,IGF1,SIRT7,SKIC8,CALR,CHCHD1,GRSF1,GSTP1,VDR,BAK1,NUDCD3,B4GAT1,INPP5E,HDAC3,ORMDL1,ATG7,RPL10,MTAP,MGST2,DNAJB6,OCRL,AQP11,DHX16,HM13,B3GALT4,ST3GAL2,DNAJC3,RAMAC,SRD5A3,CDC73,B3GALNT1,DNAJB2,LPCAT3,RBM34,PAX6,RIGI,PAPOLA,GFPT1,MAD2L2,URM1,EDNRA,RPL27A,WNT10B,TAPBP,PNPLA8,EXOSC1,PIGW,ACP6,RPL7A,GTF2A1,PRKAG1,TUFM,NCAPG2,NUS1,SLC35C1,MED27,COPS2,RPLP2,GGPS1,AKT2,HS3ST5,FUT1,DHPS,ERRFI1,DLAT,AGPAT5,RCL1,FOXP3,CLIP3,SF3B4,RPL12,SMN1,DUS4L,TENT4A,ACSL4,POP5,NKX3-2,CYP27A1,THOC6,CHAC2,DNTT,POLD4,IMMP2L,DDX1,MMP14,ZDHHC14,ABHD4,POLR2C,AGPAT1,NDST1,IL6,UTP6,HEXA,TRAF3IP2,EIF4E,GP9,NOP58,DDX39B,DEGS1,PADI2,ADAT1,SEPHS2,PAIP1,CDIPT,LSM5,CCNH,MRPL13,GTDC1,APOBEC3A,C1D,MRPL12,SGMS2,MRPS9,PRPF31,FKBP4,ST8SIA5,TBCEL,MRPS25,RPS13,TRMT10B,VPS54,RPL7L1,AKAP8L,DPP4,YIPF5,PPIF,MECR,TRMT6,GLRX5,MGAT5B,MRTO4,GCFC2,RPL10A,NPPC,HPGDS,WBP2,DNAJC1,RBM42,KIN,POLR2B,EIF5B,PIH1D1,PIGA,RDH10,EXTL2,HSD17B3,MAK16,SYK,ARFGEF1,NOC4L,PCYT1B,MED10,HNRNPL,SCG5,SGF29,ZDHHC17,MRPL17,DPM2,TESC,NOL7,EAF2,INTS12,FOXA3,POLDIP2,ZC3H11A,CCAR2,SELENOT,MED22,PPIC,APOBEC3C,VSIR,APEH,LHB,MCAT,RBM17,TCEA1,CERS2,XPO1,MRPS18C,GLUL,MED9,GPAM,TRMT112,MRM2,CNOT6L,FA2H,PRKAB1,MED23,NPC2,ST3GAL5,PIK3R2,AGK,CUL3,PIK3R1,CCDC47,CPSF2,CTNNBL1,CAPN2,PIGY,NIBAN2,HS2ST1,DEK,ELOVL4,TCP1,STT3A,PTDSS1,CDC40,TRUB1,MRPL49,RPS11,UNC45A,HSPB6,RPS12,ABHD2,GTF2E1,RCE1,BCL9,PPM1B,RRM1,GTPBP2,FABP5,EIF3E,MRPL41,HMGCS1,RPL31,MGST3,GTF3C4,SAMHD1,CHTOP,GTF2H2,CHST1,WRAP53,TOR2A,TRMT11,UTP25,BACE1,RPL35A,ABCG2,CD40LG,HSD17B8,PIK3CG,HNRNPA2B1,RBM41,VAC14,F7,WDR12,PIK3CA,TAF10,ELOVL3,FIG4,RBMS2,NUP107,APEX1,CHST13,SUPT4H1,THOC1,GFM2,GNPAT,MAGOHB,CYP39A1,WDR55,RPS10,DECR2,ADRM1,PRCP,GPX4,CWF19L1,AIP,MRPL9,TECR,MTF1,HYCC2,HSPE1,MRPL36,CISD1,ETNK2,CDK7,SMAD1,PFDN2,CCT2,MACROH2A1,ILVBL,COIL,WDR3,AHSA1,FOSL2,SNRPE,METTL25B,HNRNPC,COPS5,SNRPA1,GAL3ST1,NFKBIB,GCLC,QNG1,NPM3,TTC4,EIF2D,PXYLP1,EIF3J,FMO1,GSTM2,PIWIL2,MPDU1,RP9,RTCB,PDHB,FARSA,ZDHHC24,CREBBP,PROX1,RPL22,POLB,SNRPD3,DPY30,PLSCR3,SRPK2,KRAS,GTF2H5,MRPL40,METAP1,PPP1R3C,DTWD1,PCNA,SNAPC1,TWNK,RPP21,DRG2,IL2RG,TCEANC2,ZCRB1,IRF9,MPHOSPH6,ZMPSTE24,CYP2D6,RBM22,BUD31,ALKBH5,BRCA1,SMAD2,TAF2,WBP11,YBEY,SNRNP70,POLR2I,SNRPG,SNRPA,MRPS23,APOBEC3F,ARB2A,RPS27L,MRPS21,PSEN1,MTM1,EGR2,SLC19A2,RNF113A,PFDN6,SOCS3,PRDX4,COQ8B,MTG1,RBFOX2,FCF1,MRPS33,NDST3,SMG5,CD28,CBFB,HSP90AB1,NAA60,FKBP1B,CDKN2D,POLR3H,SMPD2,RPP14,ST3GAL1,SNIP1,ATP6AP2,POLR2D,OST4,OAT,INPP5K,HSP90AA1,NFIL3,MED21,USP15,EIF2S2,POLR3GL,SOCS4,PWP2,DAD1,WDR45,NAA50,SPON1,MRPS28,DNAJC19,HNRNPA1,WWP2,PMPCA,MRPS26,MRPL16,THOC2,ACTMAP,CREB1,SELENOF,TYW5,RPL23A,MARS1,SLC25A1,SCNM1,HSPB1,TDRD7,PTGES,SLU7,HSPB2,KTI12,SCN2B,WDR83OS,LMAN1,DIS3L,MTRES1,LDB1,EIF4E2,RPS16,BOLA2B,PPIH,PIP4K2C,POMT2,ACOT8,HSD17B1,PLSCR1,RPS28,EEF1B2,TSEN34,RPF2,FRA10AC1,INPPL1,ELOVL6,HSP90B1,SPHK2,PPAN,TRA2B,SPCS1,OGG1,QRSL1,ANKH,TFB1M,ZDHHC8,MME,DFFA,RPS29,H2BC1,KLK6,PIR,GTPBP1,S100A10,HNRNPH3,CD226,PRPF4,DPAGT1,CARS1,BATF,BRIX1,PYCARD,NAA15,ZC3H15,POLDIP3,ADIPOQ,GALNT2,SRSF8,SRSF2,MSX1,EEF2,RPS3,PPP1R1B,ETF1,SPCS2,GLE1,TSPO,KDSR,GOLGA7B,SLA2,HDHD5,POLE4,PPARG,LIPA,ACOX1,ST8SIA4,CYP7A1,B4GALT6,RPL23,TAMM41,CCNA2,EPO,PTGDS,LSM6,POLR2L,MNAT1,CLN8,NR4A2,MKKS,MYRF,IKBKB,EGR1,CHCHD4,RPS5,PYCR1,NCSTN,EIF4H,RPS20,EDEM3,MRPL47,AASDHPPT,PSENEN,NDUFAB1,COMT,HELT,TBCE,FGFR1,SRSF1,MTHFD2L,CMTR2,ATXN1L,GGTA1,ACSS2,RRP7A,PIWIL4,POLR1B,MRPS18A,TSEN54,DDIT3,FKBP10,SEC11A,UGDH,POLE3,DNAJC2,NONO,ABCC5,TAF7,PFDN1,CHST10,SPPL3,FKBP8,NOP9,ERCC3,IDO1,ZMAT5,PEDS1,VPS72,PGAP4,RIOK2,MRPS18B,POLL,EIF2AK2,CDK12,GAMT,CYP2C8,GYS1,ATG4C,RIC3,RRN3,TRIM24,PTEN,JAK2,CHPF,MED31,DDX39A,TSPAN15,INTS6L,GALNT17,TSR2,SPTSSA,EIF3G,KPNA6,AKR1A1,POLR1D,TUBA1A,ABCE1,ACACA,B4GALT7,BAD,UGCG,DPH3,GON7,MRPS35,NOP53,PYCR2,AKAP17A,RPS27A,PDIA2,LSM4,PRMT5,GRB10,SMAD4,ISG20,MRPS34,RFC3,MAGOH,CERS6,EP300,DR1,RPSA,GEMIN8,KARS1,COQ10B,POP7,HSD17B10,PRKD3,RPN1,WDR77,NAA16,CSTF3,PIK3R3,EIF3D,SLC1A2,SHLD1,SLC1A1,CRTAP,RPF1,CTNNB1,CYP2R1,CYFIP2,TMEM106A,TSNAX,RWDD1,ESS2,PCK2,CREBL2,TIA1,HACD3,NGDN,SYNCRIP,WDR82,ELP6,PHKG1,ENPEP,RPS2,EEF1G,ECD,RBFOX3,MRPL22,INHA,METTL2A,RPS23,MED29,KHDC4,HSPA13,LYAR,SNAPC3,ELK1,ELOVL7,EIF4E3,RPL26L1,MPHOSPH10,POLR3F,BAP1,SNAPIN,H3C1,RPLP1,RMND1,SRSF10,RPLP0,HYPK,LIG3,HAS3,MAT2B,MRPS7,AURKAIP1,HSPD1,IMPA2,EEF1A1,MRPL11,LUC7L3,THUMPD1,GAL3ST4,SLC1A3,RPL39,OSGEPL1,ST13,STOML2,ASMT,THRAP3,RNF14,SNRPB2,RPS17,POLR3B,RNASEL,DUOXA2,GTF2F1,NANP,ERP29,VIRMA,TSR3,MRPL24,ZDHHC16,FAM20B,DNAJC7,THBD,GSTM4,CD2AP,TTC1,FMO3,FKTN,DNLZ,NDP,CSGALNACT2,NAA11,CHKB,SELENOI,GRM2,TXNL4A,UTP23,TMEM59,ACAT1,UGP2,RPL32,PRSS12,FOS,TFCP2,CLPX,BMPR1B,PRSS37,MRPL18,SNRPD2,RPAP2,CYP2C9,HNRNPF,CBR4,GTF2E2,TERT,THTPA,KCNJ8,HS3ST1,NFKB1,EIF2S1,RPL24,FUT9,B3GNT2,MGAT4A,ALOX5AP,MRPL20,P3H1,LIPT2,MRPL33,PABPC1,SUPT3H,PLP1,ZDHHC4,CLU,MED30,SDS,RPL3,CISH,WDR83,RPL19,DNAJC4,ELP3,PKNOX1,RPS7,AKR1B1,SNRNP27,TYW3,GRPEL1,ATG16L1,CMTR1,ATG4A,PCBD1,GPAA1,SMAD3,TRMT1L,EIF1AX,EIF4A3,SNRPN,TAF9,POLD2,HNRNPD,SELENOK,NXT2,ELOC,KRR1,GTF2IRD1,ALYREF,TMEM208,MAN1A2,PIGK,C1GALT1C1,UTP15,SLC30A5,IRF1,DTWD2,PQBP1,DNAJC5,CCT5,ASNSD1,TFIP11,SNAPC2,IFI16,RPS24,TLCD3B,PGK1,METTL14,EIF2B5,NBN,RPP25,PGS1,EIF3K,MGAT1,EIF1AD,HS3ST3A1,DNAJB4,GCNT3,MECP2,SMARCB1,NOB1,IVNS1ABP,HACD1,B4GALT4,GOLGA7,SACM1L,UBL5,SLC38A1,ADGRG1,BMPR2,DRAP1,CELF6,SRSF4,EXOSC3,MRPL50,PDIA6,NRDE2,MTMR2,SRGN,PDSS2,CSTF2T,PTGES3,GXYLT2,EXT1,SERPINH1,ANGPT1,PIWIL3,SMARCA5,PPID,EIF1B,SRC,PPIL3,CHPF2,MRPL51,ISCA2,TCOF1,METTL6,PSEN2,HNRNPK,SQSTM1,POLR2G,SF3B6,MGAT4B,ATF4,NOVA1,POLR2F,SNRPB,DTL,RPL8,TENT2,ZRANB2,RBM27,GALNT1,MED17,SERINC3,FAU,MRPL53,MEF2A,ELOF1,PRKRA,DHX38,CPSF1 |
| 8.845e-09 | -18.54 | GLRX5 (glutaredoxin 5) | protein interactions | 51218 | 80 | 47 | 19454 | 5460 |
CLIC4,PRDX2,CTSB,TXN,TXNDC12,WDSUB1,ARF1,ENO1,BOLA1,FXN,RIT1,GLOD4,ATP5F1A,MTPN,ISCA2,ACO2,PMPCA,CRYZ,HSCB,NME4,SRI,SDHAF4,PRDX6,BOLA3,GSTP1,IDH2,DHRS4,GABARAPL2,LAP3,SPR,GATD3,AIFM1,COX4I1,AK2,MPST,IMMP2L,CHCHD2,GUK1,KRAS,HINT2,HINT1,HSPD1,TCOF1,MSRB3,NDUFS3,HADH,CMPK1 |
| 8.919e-09 | -18.54 | ATG4B (autophagy related 4B cysteine peptidase) | protein interactions | 23192 | 119 | 63 | 19454 | 5460 |
GABARAP,EIF4E,STAU1,RPS15,SQSTM1,NUP50,RPL27,NUFIP2,RPLP0,RPA2,EIF3J,GABARAPL2,CNPY3,RPL22,RPL19,RPL10,PSMD6,RPL13A,RPS12,GTF2F2,GTF2F1,RPS9,SRP54,EIF3K,RPS3,CCNF,RPS5,RPS26,H1-10,ATG3,FBXW11,FAS,BAG3,MYC,RIGI,RPL17,RPL28,RPS13,RPS4X,DHX9,COA4,RPL3,PABPC1,RPL31,STK16,RPS23,RPS7,GABARAPL1,MAP1LC3B,CSNK1E,STK3,PRNP,RPS16,TES,MAP1LC3A,MGME1,RPL32,RPL9,YWHAB,RPL23,RPL24,RPL6,MOV10 |
| 9.099e-09 | -18.52 | negative regulation of epithelial cell proliferation | biological process | GO:0050680 | 174 | 87 | 18204 | 5365 |
MIR30E,RGCC,IFT57,MIR342,CDKN1B,MIR193A,MIR146A,CDC73,MIR21,MIR30B,SFN,MIR503,AQP11,PPARG,MIR149,WNT10B,MIR181C,CAV1,PAX6,MEF2C,B2M,MIR129-1,KLF9,IL12A,SCG2,MIR132,ATP5F1A,PRL,VASH1,STK3,CDK6,KRIT1,PHB2,IL12B,STK4,MIR133B,IFT52,CASK,MIR15A,NUPR1,MIR34A,MIR126,FLCN,SFRP1,SYNJ2BP,IFT172,MIR222,SOX9,GHRL,RGN,MIR492,DLG1,AR,TRIM24,MIR497,ATP5IF1,SNAI2,CAV2,STAT1,B4GALT1,CCL2,MIR29C,LIMS2,RB1,MIR424,MIR16-1,SAV1,TMIGD1,SOX2,MIR205,MIR495,DUSP10,MIR361,STK11,MIR152,EAF2,MIR98,NKX3-1,FBXW7,OVOL1,WDR77,TGFB2,MIR24-1,TNF,PDCD10,IRF6,VDR |
| 9.177e-09 | -18.51 | SLC25A1 (solute carrier family 25 member 1) | protein interactions | 6576 | 258 | 115 | 19454 | 5460 |
AGR2,RHOG,HSPB1,PEX3,KRBOX4,WWP2,DDRGK1,CTNNB1,MAP3K14,YWHAH,RHOH,TCP1,PCSK9,HSP90AB1,EGLN3,ELK1,PHB1,RPL9,RPN1,RHOBTB1,RND3,B3GNT2,RAF1,ERLIN2,TUBA1A,SOX2,RUVBL1,TNF,G3BP1,RFC3,RPS4X,NDUFA4,CCT8,BCKDK,HSPD1,RUVBL2,RHOB,CCT2,ILK,RPS5,RPS26,RAB11A,CUL3,MYC,TUBB,ESR2,MAD2L2,PELO,LMBR1L,PPT1,PIH1D1,CSNK1A1,BET1,RND2,UFL1,COIL,XRCC5,BMPR1A,HDAC5,HSPA8,DPP4,HDAC6,CGAS,CAND1,CAV1,TMPO,CDK9,CD274,RAC2,LDLR,TFRC,SLC25A20,CCT5,FAM162A,CDK4,FBP1,RBCK1,ARF4,SFXN1,SLC25A11,SPOP,UBE2H,ATP1A1,RALB,GMPS,FBXO7,RHOJ,MGST3,DYRK1A,VIRMA,SRPK2,SH3BGRL,ENO1,CCNF,PTEN,PTPMT1,SEC61A1,GANAB,HSP90B1,LMNA,RPA2,ATG16L1,CDK7,CFTR,CDC42,GABRA1,SMC4,FBXW7,NF2,AATF,HELLS,RHOU,RPA3,SQSTM1,RNF113A |
| 9.181e-09 | -18.51 | CIC (capicua transcriptional repressor) | protein interactions | 23152 | 671 | 255 | 19454 | 5460 |
HNRNPF,RUVBL1,SATB1,CCAR1,RPS4X,PAX6,CCT8,LSM14A,TRIM21,EWSR1,RUVBL2,PICK1,PDIA6,RTCB,IRF8,PNMA2,MTA2,HGS,RPS23,TOP3B,PTS,SUPT5H,SOX2,RPS7,EEF2,HNRNPL,ZNF740,SNRPD3,SUMO2,HSP90AB1,SIN3A,CORO1C,DDX1,YWHAB,DDX50,YWHAG,YWHAH,EEF1G,RFC4,XRCC5,FOS,SF3B1,HSPA8,TRIM22,DDX5,CTBP1,EIF4B,SEC62,ZNF362,MATR3,NDFIP1,CBX5,POLR2B,ACAP2,ESR2,PHF12,ATXN1L,ZNF189,ZMYM2,SMU1,PRMT5,PHF21A,CCT2,CHTOP,HNRNPC,LDB1,BRMS1,SNRPB,NUP107,HNRNPK,TMEM33,KPNA2,CAPZA1,SLC25A11,SLC16A1,DHX9,CHAMP1,CBX3,TFCP2,IK,TP53,RPSA,ACTR1A,IKZF5,RPS16,BRMS1L,TMPO,CDC5L,SYNCRIP,ADD1,SMAD4,SMCHD1,RPS2,AKAP8L,KPNA1,RBFOX3,ZNF24,RBM17,CSNK2A1,RPS15,KDM1A,STK38,HSPA5,POLR1H,RPL27,HNRNPH2,PRDX6,RPA2,ZNF326,E2F6,SPTBN1,GTF3C4,IRF2BP1,BUB3,DYRK1A,SRC,CREB1,RPS3,SF3B6,CDIPT,LIG3,ZBTB33,ING2,CSNK2B,EIF3G,NR2E1,ATP1A1,SMARCA5,PSMB2,SLC25A1,CCNB1,RPS17,RBBP7,ZNF592,GTF3C3,RAD21,PCGF6,MSL2,SSRP1,RFC3,SLC25A5,MORC2,JAK1,BAG2,RPS24,RPN1,RBPJ,RPS11,GTPBP1,PPP2R1A,JUN,SAP30,NOP58,CCAR2,LRWD1,NUP35,DHX15,THOC2,PPP2CB,RB1CC1,RPL23,LHX2,DYRK1B,PRPF19,ZBED4,PRDX1,EIF3D,ZBTB39,CMAS,ASB3,THOC3,ZFP64,APOBEC3C,KLF3,ADNP,SLC25A3,ACTL6A,WDR77,PRDX2,RBBP4,MAD2L1,ELK3,PELO,SNRPD1,RPS9,SEC61B,YWHAZ,LMNB1,RPS5,HSP90AA1,HNF1B,RFC5,PRPF31,ATF1,MCM3,HUWE1,THRAP3,FARSA,EIF3E,PRDX4,SLC25A10,TGIF2,RING1,GABPB1,SAP30L,MTA3,YTHDF2,ING1,DDX39A,EEF1A1,SOX9,PRNP,SRP14,SMAD3,UBP1,RB1,DNAJC7,ORC5,IRF4,MPG,NPM3,GTF2I,RPL4,MBD3,RPA3,H2BC12,JUP,LMNA,CDK1,PAX9,RPLP0,RPS14,SF3A1,KLF12,CNP,ZBTB17,VIRMA,STUB1,ZBTB18,RPS12,RPS20,ALB,IVNS1ABP,CSK,STK38L,SEC13,ZNF687,PYCR2,ATP5F1A,RUNX1,AR,NONO,GMPS,PPP1CC,TUFM |
| 9.336e-09 | -18.49 | ARHGEF16 (Rho guanine nucleotide exchange factor 16) | protein interactions | 27237 | 92 | 52 | 19454 | 5460 |
HNRNPL,HACD3,HRAS,COQ8A,SNRNP70,YWHAB,DDX1,QPCTL,XPO1,YWHAG,PPIB,PPIL4,YWHAH,MAPK1IP1L,KPNA2,ATP1A2,LASP1,CHCHD2,TFG,RPS27A,DLG1,RTCB,ABCE1,PDHA1,PLS3,LYPLA1,LBR,TAB1,ELMO1,TOM1L1,MRPL53,ACAT1,YWHAZ,RHOB,MECP2,MAPRE1,EPHA2,SFN,AKT1,PML,LIN7C,TMEM160,DLAT,HSPA8,ATP5PO,LMNA,RPA2,RABL3,ATG16L1,RBFOX2,SF3A1,CDC42 |
| 9.360e-09 | -18.49 | NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor) | protein interactions | 4771 | 375 | 156 | 19454 | 5460 |
SLC25A5,CDKN2C,TRIM21,CDK5,KRAS,UBE2A,RPS4X,SSRP1,FLOT1,RFC3,TOP3B,RAF1,SOX2,NCSTN,ERLIN2,RPS7,SCHIP1,GTPBP1,RPL18,HGS,RPL8,RAB35,PHB1,TSG101,S100A8,GJA1,TYMS,HNRNPL,DHX15,LAMP2,PRDX1,PRPF19,SAV1,WWP2,XPO1,CTNNB1,CBR4,RHOG,AK2,WBP2,XRCC5,TERT,SOX3,NOP53,STAU1,STX7,G3BP2,TANK,PALS2,VPS18,SLC25A3,SF3B4,DYNLL1,RBBP4,TSN,ESR2,RPL10,APEX1,MYC,RHOB,NTRK3,KCNA3,SP1,RPS5,RIT1,SLC25A11,RPL3,RPL23A,IGF1R,HUWE1,KPNA2,FARSA,VTA1,PREB,TP53,CDK4,MAP2K3,RPL15,GPD2,TFCP2,NHERF1,NUPR1,SMAD3,SRPRA,HRAS,ARL10,RAC2,CDK6,FZR1,GRM1,TOP1,TSPYL4,DBT,TMPO,SLC25A12,CAV1,GRSF1,MOV10,DPP4,LANCL2,BECN1,AKAP8L,RPS2,LIN7C,LSM12,HNRNPH2,DLAT,UBE2K,NF2,KDM1A,RPL4,GRPEL1,SPTBN1,PPP1R8,JMJD8,CD2AP,KDELR2,CDC42,EIF3J,CDK1,SDCBP,RPA2,FGFR1,CHMP1A,RNF146,PDCL,MET,DYRK2,RARS1,PRKCA,HECTD1,LUC7L3,RPS3,PSPC1,LURAP1,LIG3,CALML5,ODR4,SFXN2,GMDS,RPL13A,RHOJ,UBA3,VIRMA,SLC25A1,AKT1,RSPH1,PYCR2,DNAJC5,AGAP2,PIP4K2C,IGF2BP1,EPHA2,PTTG1,STK11,NRP1 |
| 9.370e-09 | -18.49 | extracellular space | cellular component | GO:0005615 | 3443 | 1138 | 19108 | 5553 |
CAMP,NDNF,ALPL,NRP1,GNPTG,PSMA1,WWP2,RHOB,EIF4E,FAM3C,MIR10B,RRAS2,LEP,SPP1,HMGB1,APOO,MIR338,CSE1L,NECTIN2,DDAH2,GLE1,CUL3,PLAA,CD1B,SERPINH1,KRIT1,CMBL,CALR,MIR130A,PROM1,HBEGF,IL6,RPLP0,PPP2R1A,FAS,SEMA3C,SIT1,PCSK2,MIR340,CHI3L1,RAB4A,MBD5,MGAT1,MIR1296,CAPZA1,CMTM7,BPGM,SNX18,AP1M1,ST13,C9orf72,VLDLR,MME,TOM1L2,CCL5,PI15,ZBTB38,CYB5R1,S100A8,MIR425,PSMD3,NUDT1,FGF7,EIF2S1,MIR183,PPIA,CXCL12,DIPK2A,TPT1,MIR378A,CBLN2,MIR192,GREM1,F2,MIR100,PMP2,REN,CTSC,RPL23A,RPLP2,AOX1,TOM1,STC1,RAC2,GOLGA7,MIRLET7C,H2BC14,ZMPSTE24,PSMB5,STAU1,GNA11,MIR505,H2AC13,PPY,FABP4,DDT,LCP1,MIR99A,H3C1,SELENOS,RPS20,CCL17,DNPH1,DDR1,TSG101,KRT7,TSPAN3,FLOT1,GAL3ST4,EPCAM,PGAM1,YWHAH,BGLAP,B4GALT3,RNASE1,RPS28,SH3BGRL,WFDC5,CAPZA2,FAM3A,MIR503,SNAP23,INA,MIR4446,ATP6AP2,CTNNB1,TXNRD1,HAPLN2,RPL26L1,GLIPR2,HNRNPC,MIR204,VEGFC,PSMB9,AP2M1,MIR454,ESD,CSNK2B,IFNG,MIR34A,MDH1,PATE4,APLN,HSPA8,PPFIA2,MICB,PI16,ARHGAP1,GPX4,BMP1,VPS4A,MYL6,CD38,MIR148A,TTR,APOC2,GSTCD,ACAT1,GALNT4,ZBED3,FAM151B,ICAM3,SERPINB1,MIR3173,PITPNA,ACTR3B,TMED9,MIR423,MIR16-1,GNRH1,PRSS8,TUBB4B,UBE2D3,STOM,SNRPD2,ADSS2,TXN,RPS14,GNAQ,SLC2A3,CDC42,SNCG,PSMA6,ODAM,TPSG1,SERPINI1,VAMP8,VASH1,SCGB1D1,MIR125A,CYFIP2,COL3A1,SNX3,NME1,HUWE1,PPIB,FGF16,RHOG,IFNA10,MIR101-1,OAZ3,CKB,MIR937,TF,CACYBP,MBLAC2,GPHA2,RPS9,NME2,MIR23A,KRT8,FGF12,TNFSF13,TMBIM1,VPS4B,PEBP4,ADPRH,JCHAIN,GSTK1,CXCL9,PRKACB,IL21,GLO1,IL10,RHEB,RAB2A,MIR335,STK11,DEFB114,CD248,DLG3,NOG,SOD1,CHMP5,GNL1,S100A11,SST,TMEM256,MIR26B,TIMP1,TNF,WWP1,MIR502,PPT1,GMDS,CNP,HBB,AASDHPPT,FTH1,FBP1,LILRB4,IRF6,CBLN3,OXSR1,CD63,CELA3B,MIR210,ENO2,PRCP,CLIC4,SSBP1,MIR638,MIR181C,MTAP,GPX3,CDK1,MIR10A,IFI35,RPS29,MIR194-1,SVIP,RNASET2,GABRB2,APOC4,IL23A,NAA50,FGF23,RAB22A,YWHAB,AKR7A2,AHSA1,CXCL11,CBLN4,AZGP1,TGFB2,LMAN1,IRF2BPL,EIF3E,SPOCK1,C1QTNF1,AKR1B1,SLC25A3,CTSK,MIR590,VDAC1,BPIFA2,LGALS3,OLA1,FAM234A,CPE,CCL28,RPS13,THY1,KDSR,IGF1,MIR24-1,TUBB,RAB11A,RUVBL1,COMT,NPC2,EEF1A1,FUT8,IL5,SRI,PRNP,MIR215,MIR619,PABPC1,THRAP3,NEDD8,MIR361,TST,CAB39,MIR384,SERPINB6,ZNHIT6,TCP1,MOXD1,TIMM8B,PRSS1,EPS8,PDZK1IP1,LDHB,MIR222,LRRTM1,C1QC,RAB3D,RAB6A,THBD,CSK,MIR17,RPL39,STK26,LRRC3B,SOD2,GNG2,MIR532,ATP5F1A,PRDX2,LCN9,PCNA,RAB11B,SCPEP1,HNRNPA1,PSMA2,DUSP26,HSPD1,S100A6,CD58,LAP3,RPS4X,MIR152,NPY,GMPPA,TNFAIP6,CBR3,ZNF177,HEBP2,GCA,PEBP1,ATP1B3,CSRP1,PMPCA,MIR106B,CRYAB,RPL26,PNP,SFN,TUFM,MIR144,ARPC2,CTNND1,MIR29C,MIR106A,PAFAH1B1,RPL3,TOR1B,VAMP7,APEH,SLC16A1,TAGLN2,H2AC25,ARPC3,CFAP20,GNAI2,TWSG1,AIF1L,FABP5,PLCB1,GSTP1,MIR1249,MIR146A,PALS2,IFNA2,YWHAG,GSTA2,IGFBP4,FLRT3,NCKAP1,C1GALT1C1,RAB29,OLFML3,ACP2,AK2,SPON1,TOR3A,RAP1B,KARS1,DKK3,ADAMTS20,PSMB4,MIR92B,AKR1C1,MIR208A,IRAK4,USP14,PDCD10,MIF,CCT7,GCNT3,UPK1A,SHMT1,FLRT2,HEXB,BST2,MGAT4A,PRDX6,PTN,CEACAM5,IL3,F7,PRRC2A,GNG12,PPP1CB,FGF17,ATP1B1,PSMB1,ATXN10,ATP6V1C1,IL22,RPSA,IL34,IL7,WNT2,H2AC7,SEMA4C,CCL21,TXNDC17,LAMP2,RALGAPA2,MIR1234,ALKAL1,HINT1,MIR20A,MIR877,FCN2,EHD1,CPNE2,RNF11,FBP2,HIRA,CYBRD1,RUSC2,MRPL18,CREG2,SLC15A2,B4GAT1,CCT2,FKBP4,LRRC24,CCT5,RAB5A,ADGRG1,NCSTN,GHR,SH3BP4,SOD3,FAM168B,RPL37A,GNB3,VAMP5,FAH,LYPLA2,CXCL1,OGN,KLK6,RHOJ,IFNK,DEFB1,TGFB3,FMOD,PDIA3,CD81,BPIFB1,MIR132,LUM,DPEP1,SERPINA3,PACSIN3,CDNF,MIR29A,MIR139,PYGM,DBH,GLIPR1,IL13,PAFAH1B2,DNAJC3,PRELP,CCL20,ABCB1,GGCT,CXCL8,CCL4L1,ACTR2,CDH13,RPS26,MIR150,CXCL13,GBE1,ADNP,PSME1,SLC12A2,MIR126,PTHLH,CD36,MIRLET7G,GSTM3,LHB,NCR3LG1,PSME2,HBA1,KLK5,PBLD,ITGB5,LGI1,AQP2,PTGDS,FGF1,TFRC,STAMBP,ANXA4,MIR24-2,CCL1,GK2,IDE,MIR30E,MIR186,LGALS8,SRSF7,NAA16,GSTO2,MPST,ANGPTL2,GSTA1,RPL27,MIR142,FGL2,ANGPT1,GAPDH,SFRP1,BTG2,GDPD3,TNFSF15,SLC35F6,CUTA,HSPA13,CAPN1,ANP32B,CRTAP,LYZL4,H2AC6,GNPDA1,CAPG,MOV10,CFL2,TNFAIP3,TFPI,UGP2,ACTA2,VPS28,PRDX1,SRGN,CD1E,CCL18,MIR9-1,PDIA6,SLC22A12,MSMB,MARCKSL1,CRISP1,GGH,CTSB,CMA1,WNT7A,ALYREF,YES1,CD1D,LYZ,PPIC,MIR339,GSTT2B,FASLG,UBE2V2,ATP6V1D,BAX,MYL12B,NAPA,MIR15A,RNASE4,GNAI3,CXCR4,PDE8A,MIR191,GRID1,TOM1L1,RARS1,SFTPD,HEBP1,VWF,FKTN,EEF1G,RAN,MIR197,LAMB2,SFTPC,MIR424,MIR625,CD47,SFRP4,SLC1A1,TIMP3,IL12A,LXN,PADI2,ATP6V1G1,NUDT9,MIR421,GANAB,PSMD7,LAMTOR1,LECT2,AKR1A1,FRZB,LDHA,DDX23,CRYZ,PATE2,SRC,MIR98,LAT2,KLK3,RPS5,ALDH1A3,CD1A,CHMP2B,PLD3,ABHD14B,CX3CL1,CD40LG,MAN1A2,CSH1,PRRG1,MIRLET7B,MIR205,SEC13,NTF4,TLR3,IL6ST,ATP1A1,TAX1BP1,ENPEP,RAB27A,CA2,HILPDA,RAB5C,HNRNPL,GHITM,SFT2D2,ENO1,CSTB,MIR25,SERPINA5,HNRNPK,RHOBTB3,CHMP2A,CXCL10,CKLF,ARL15,RAB35,CHCHD3,SERPINB10,UBE2N,RAB9A,PRKCB,MMP28,CYTL1,MIR141,GPC4,MIR16-2,UTS2,LTA,HBE1,SORD,ENDOD1,GNB1,ARF1,RALA,PSMD12,ACSL4,IGFBP3,LYPLA1,AMY2B,PDCD5,DES,LGI3,MSTN,MIR30D,MIR769,SLC20A2,IL1B,P3H1,MIR652,MGP,DKK1,RS1,S100A10,CRABP2,FKRP,GNB4,CER1,VTA1,ELFN1,SLC25A1,CTSD,RPL24,FGF22,ALB,COL1A2,GPT,CDH11,MIR140,NAPG,PYGB,CSTA,RPL4,RAB19,CHGA,RPS2,REG1B,MIR375,TOLLIP,ACO1,SERPIND1,RAB8B,SRPRA,ABHD8,RPS27A,SLC22A8,ST3GAL1,YWHAZ,RAP2B,MIR185,SQSTM1,EMILIN1,OLFM3,CCN3,H2AC4,CD86,CLTRN,CXCL3,MTMR2,WNT10B,IL15,RNASE6,SCG2,BMPR2,CCT8,UBB,PSMB6,XCL1,DPP4,AGR2,CTSA,IL2,STK24,ACTR1A,H2BC11,TNIK,RUVBL2,CD1C,NEU1,SEPTIN7,CXCL14,MIR342,GPRASP3,ICAM1,CRHBP,B2M,PLG,CRB3,ACHE,ATP6V1A,CHMP1B,LCN12,SPTAN1,CRYM,CHID1,G6PD,DNAJB9,RPL12,GFPT1,SOSTDC1,UBE2V1,OSM,TIMP4,SLC2A1,FAM20C,MEST,ITGAV,SAMM50,MIR182,CMPK1,HFE,TMEM59,PSMC5,NCOA5,GABBR1,RALB,CTDSP1,SELENOP,CHMP1A,MIR589,MIR99B,GNG5,RPS11,CCL2,HSP90AA1,IDH1,H2AZ2,TNFSF12,DLG1,GPM6A,PGM1,WASF3,NIBAN2,MYO6,RHCG,LCN1,IL4,GSTM2,F11R,GLUL,ARF4,CD14,PGA4,PRKCA,IFNB1,MBL2,MYO1B,MMP20,DAG1,NELL2,MIRLET7D,RAB1A,RPL31,WASL,AGA,JUP,FGR,EPO,SIAE,AHCYL1,CD59,PI3,RPS3,RPL23,REG1A,GNA14,FOLR1,HSPB1,HP,ALCAM,PRL,MIR874,HNRNPA2B1,ACTN4,CLU,MIR223,SPR,ENPP4,CCL23,RPE,RAP2C,MIRLET7I,GSTO1,MECP2,MIR181D,GHRL,MIR374A,CAND1,ERO1A,CIB2,HSP90AB1,FURIN,CCL19,LRRTM2,ACTR1B,CD40,DDX5,PGK1,MIR221,DDAH1,NMI,GSTT1,EHD4,SDCBP,HSPE1,H2BC9,HSPA5,MIR28,MIR331,TSPO,OLFM2,PSMB2,RARRES2,TNFSF8,RBP5,UBA52,FGFBP1,IL18BP,MIR30B,CFL1,MIR130B,PSMB3,MIR370,ECRG4,SLC22A6,H2AC1,IL17F,WFDC13,PLSCR1,SLC38A1,SERPINC1,GDI2,RAB1B,CSF2,TAX1BP3,FGF10,GREM2,HTRA1,SLPI,MIR136,RPL22,ITGB8,MIR320A,ARF6,MIR671,CCL8,ACTB,MIR636,SERPINB9,PRSS23,SEMA5A,MIR301A,KIT,DNM2,MIR145,RP2,CD2AP,MAT2B,KIF3B,MMP9,CRTC2,F10,CRYL1,FSTL1,SCAMP2,ADIPOQ,RAB13,RACGAP1,SEMG2,MSMP,FGF3,H2AX,ALDH1L1,CPNE1,DICER1,PCSK9,MIR493,FBLN5,HEXA,GNG7,CCL3,MACROH2A1,IL12B,TAC1,ATP8A1,MIR148B,IDH2,UGDH,IL18,PSMA4,AGAP2,STXBP1,TPM3,MIR628,CCL24,CAPN2,LAMTOR3,MMP14,MSN,GLOD4,MIR30A,CNTN1,RAB14,DSTN,RPL28,MIR21,GH1,PSMA5,CCL25,CD9,STX7,CNDP2,MIR1-1,HSP90B1,CLEC18A,RPL10A,CD79B,UBXN6,H2AJ,MIR345,FTL,FAU,GNRH2,GPC1,ATP5F1B,PHB1,SUB1,LRRC57,CCL11,MIR500A,MIR193B,SERPINB11,SFTPA1,ARL6,MYL12A,LACRT,RETN,CST3,EEF2,ANXA7,TOMM70,DNAJC7,VEGFA,COTL1,IFNA13,HNMT,CD46,B4GALT1,IL1A,MIR212,CYSTM1,HGS,MIR363,TAFA1,MACROH2A2,TNR,S100B,MT3,EFNB1,MIR107,SOST,PABPC1L,SMURF1,PSMA3,RAB3B,INHA,RPL35A,LDLR,PROS1,SPTBN1,CD274,ELFN2,RPS16,CCL27,H2AZ1,MIR484,H2BC12,CARTPT,UBL3,PRDX4,PLA2G15,SDC4,MARS1,BLVRA,TNFSF10,GLRX,LRRTM3,VMO1,CPXM1,GFUS,MIR143,MIR31,CHP1,NUDT5,ITM2B,TNFSF18,SAT2,SYPL1,SERPINA1,TUBA1A,RAP1A,SELL,NDP,XPNPEP1,CYRIB,SYNGR2,PCBD1,LTB,LRRN1,PIP4K2C,F9,NPPC,MIR1304,NHERF1 |
| 9.396e-09 | -18.48 | PRP4K (pre-mRNA processing factor kinase PRP4K) | protein interactions | 8899 | 306 | 132 | 19454 | 5460 |
ZC3H11A,RPL3,SNIP1,MSH6,RPL17,MEPCE,THRAP3,LSM4,SEM1,CTNNBL1,CD2BP2,KIF1C,TBK1,TAF2,NUPR1,PPP4C,RBM34,IK,CBX3,DDX42,ALYREF,SRP14,CDC5L,CDK9,NCBP2,RBM42,TOP1,THOC1,FZR1,CSNK2A1,PPIL4,GRSF1,BRD3,RPS2,SNRNP70,CHCHD1,H2AC4,PPIH,MTDH,RNF113A,CLK1,SIRT7,PRPF4,RPA3,RBM22,NUCKS1,RPL4,PPP1R8,TXNL4A,RPS14,SF3A1,MACROH2A2,TFIP11,RPLP0,TOX4,RPA2,FGFBP1,PRKRA,EIF4A3,CTTN,ZNF330,EIF2AK2,PSPC1,DEK,SRPK2,VIRMA,PPP1R10,RPL13A,MAGOHB,NONO,PPP1CC,DEPDC1B,SUB1,TNFAIP3,ALKBH5,UBE2H,LSM6,RC3H2,SRSF7,FAM76B,POLDIP3,SSRP1,SRSF4,RPL28,HMGN4,H1-6,E2F4,RAF1,SNRPE,RHOBTB1,RPS11,ZRANB2,SMNDC1,WDR82,SRSF1,RPL8,SNRPA1,LSM5,POLR3F,DDRGK1,YWHAG,XPO1,ZCCHC10,PRPF19,MAGOH,DDX23,EP300,SF3B1,NKAPD1,SNRPA,DDX39B,SAP18,STAU1,HNRNPA0,TRA2B,H1-5,NUFIP2,MFAP1,USP39,SNRPD1,SNRPD2,CPSF1,ERH,RPL19,PRRC2A,ESR2,SNRNP40,SNRPB,PRPF31,HNRNPC,HSP90AA1,CHTOP |
| 9.405e-09 | -18.48 | HNRNPD (heterogeneous nuclear ribonucleoprotein D) | protein interactions | 3184 | 592 | 229 | 19454 | 5460 |
SMARCB1,MTA2,EEF2,H1-3,HEXA,HNRNPDL,HNRNPF,EWSR1,PABPC1,HSPB1,CBL,DDX1,AGR2,DDRGK1,WWP2,IFI16,HSP90AB1,PNPLA8,LSM5,PAIP1,RAB1B,HNRNPL,EED,FUBP3,PIH1D1,EIF4B,GTF2IRD1,MAP2K1,CTBP1,MRPL12,TOMM22,SAP18,STAU1,UFL1,HNRNPA0,EP300,HSPA8,HDAC5,RPS28,XRCC5,HIRA,SNRPA,H1-1,ICAM1,FBXW11,H1-10,SLC30A5,SNRPB,CUTA,HNRNPAB,SFN,HNRNPC,MYC,POLR2B,TAX1BP1,SNRNP40,MATR3,SF3B4,VDAC2,VEGFA,PAPSS2,RNF8,NFE2L2,TFCP2,CDK8,ZMYM4,H2AX,RPSA,TP53,RAP1A,STRBP,PDRG1,MEPCE,HNRNPK,NEDD8,DHX9,MAP1B,TRAPPC2L,SNRNP70,H2AC4,TSEN34,GAPDH,COPS5,CD81,DKC1,CAND1,FZR1,CD4,UBE2G2,ACSL4,SSBP1,SYNCRIP,HEXIM1,UBE2M,RPA2,AGO1,CAPN1,HSPA5,RNF113A,HSPB2,EXOSC4,HNRNPH2,PGK1,BANF1,BAP1,UBE2H,IGF2BP1,RC3H2,SPOP,H2BC9,NAA50,SMURF1,GMDS,CHMP5,CTSB,B4GALT1,PAFAH1B3,GCFC2,RPS3,NGB,EZH2,ACTN4,SSRP1,IMMP2L,UBE2A,GTF3C3,ETFA,TRIM37,G3BP1,GUK1,TNF,JAK1,HNRNPA2B1,MORC2,DICER1,HNRNPD,MED4,ZNF207,HNRNPA1,HMGA1,HEBP2,CETN2,SRSF10,NTMT1,CACYBP,MPP1,PHB1,IFIT2,MYEF2,DNM2,H2AC1,PPP1CB,MYH1,PRDX3,H1-5,G3BP2,COIL,PYGB,GPC1,LZTFL1,UCHL3,BET1L,HTR1A,BRCA1,YWHAZ,SMARCE1,TOMM40,CUL3,PYCR1,CUL2,B4GAT1,MED17,TENT5C,ACTB,RPS9,RMDN3,EIF3K,SLC25A20,ILF2,TRAPPC13,ACTR2,UAP1,GGCT,FBP1,H2AJ,H2AC6,ARF4,VRK1,RAB1A,H2AC25,DNAJC7,NME2,HDAC6,MOV10,GRSF1,H2AC14,MDM2,CDK9,TOP1,PPP1R18,DCUN1D1,RCHY1,EIF4E2,PDCL,HNRNPH3,RPLP0,PICALM,H2AC7,METTL14,GABARAPL2,UQCRC1,FUT8,ATG16L1,FBXW7,PPIH,H2BC12,RPA3,NRP1,IVNS1ABP,USP14,AR,NDN,LDHA,UBE2I,RPS12,ENO1,CCNF,CINP,STUB1 |
| 9.427e-09 | -18.48 | MRPS23 (mitochondrial ribosomal protein S23) | protein interactions | 51649 | 289 | 126 | 19454 | 5460 |
GFM2,METTL15,AURKAIP1,MRPL11,TP53,STRBP,RPL17,FASTKD5,MEPCE,MRPS18C,MRPS33,H3C1,MRPS18B,DNAJC4,SNRNP70,CHCHD1,TMEM70,E4F1,COPS5,HDAC6,MOV10,GRSF1,ZBTB2,RBM42,CGAS,DCUN1D1,FZR1,CAND1,TRMT10B,ALYREF,MGME1,MRPS9,COQ8A,SSBP1,AIFM1,MTRES1,KLF4,ZNF574,TFB1M,HEXIM1,CDK1,MRPS34,KLF12,ATG16L1,CRYZ,AATF,HMGB1,NPM3,GFM1,SQSTM1,GID4,BAP1,CDKN2AIP,UBE2H,DNAJC19,IGF2BP1,RC3H2,MRPS16,SPOP,TUFM,RPL26,VIRMA,SMURF1,MRPS21,PTEN,MRPS28,PSPC1,MTA2,PDHA1,TULP3,CYB5R1,SOX2,TPD52,IMMP2L,MRPS17,COX8A,SRSF7,MRPS11,HSD17B8,HINT2,PPAN,HSPD1,ARMC8,LHX2,HSPB1,MRPS26,RHOG,SKIC8,TRA2A,DDRGK1,HNRNPA1,MRPS35,RPL6,PSMD3,MTRF1,RMND1,HNRNPL,GATD3,EIF4B,TIMM29,SYK,MRPS7,HSCB,UFL1,HSPA8,EXD2,NGRN,SNRPA,MCAT,NOA1,FBXW11,MRPS25,PSKH1,PMPCA,CUL3,AUH,MYC,MTG2,PRRC2A,ESR2,DYNLL1,RPL35,RPS9,MTG1,CCDC90B,TACO1 |
| 9.626e-09 | -18.46 | NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12) | protein interactions | 55967 | 195 | 92 | 19454 | 5460 |
HINT2,COX8A,HSPD1,NDUFB5,NDUFA4,IMMP2L,YIPF3,E2F4,CRELD1,CYB5B,RPN1,PDHA1,NDUFS6,AQP3,YBEY,GATD3,ERLIN1,UQCRH,NDUFS8,RMND1,WIF1,NDUFV2,MTRF1,MRPS26,NDUFB8,SYT4,RHOG,EMP3,NGRN,EXD2,NDUFS2,HSCB,OTULINL,TOMM22,NDUFA5,SLC25A3,VAPB,LMBR1L,BAD,TACO1,VDAC2,MTG1,CCDC90B,ESR2,PARL,ATP5F1B,AUH,MTG2,NDUFB7,NDUFB6,PMPCA,HTRA2,FASTKD5,DNAJC30,DDX39A,AURKAIP1,METTL15,MRPL11,IL1R2,MTCH2,NDUFA2,GFM2,NDUFS3,NDUFA1,SDHB,SSBP1,NDUFB4,ATP5PD,ATP1B1,GRSF1,CHCHD1,TMEM70,GFM1,NDUFC2,CRYZ,GPIHBP1,SLC25A51,UQCRC1,TIMMDC1,MPV17,HEXIM1,CYC1,MTRES1,COX6C,UQCRC2,TUFM,NDUFB10,NRP1,DNAJC19,ATP1B3,CISD1,SPOP |
| 9.639e-09 | -18.46 | NDRG1 (N-myc downstream regulated 1) | protein interactions | 10397 | 214 | 99 | 19454 | 5460 |
XRCC5,DDX39B,RAB5A,DDX5,RABAC1,EEF1G,STX7,SSBP2,TIMM13,CNDP2,DLST,RPS9,AP2M1,TENT5C,CLIC4,RAB11A,CUL2,MYC,RHOB,LAMTOR1,DNAJB6,OSGEP,RPS26,HSP90AA1,PABPC1,S100B,RTCB,RUVBL2,EWSR1,HNRNPF,UFM1,KRAS,RAF1,EEF2,RAB4A,CCR1,RAB35,IGBP1,NRSN1,TSG101,EED,DYNC1I2,HNRNPL,DHX15,CEP19,WIF1,NTMT1,CTNNB1,YWHAH,YWHAG,XPO1,RHOG,DDX1,THUMPD1,PHYHIP,MME,RPA3,BAP1,RAB9A,PRKCB,RPL4,HSPA5,TIMMDC1,STX17,RPA2,OPTN,RPS3,RPS20,RHOJ,LDHA,EIF4H,RAB2A,NAA50,USP14,AR,CCDC22,NIF3L1,ATP1B3,UBE2H,ZBTB38,ATP1A1,RPL3,FGF12,EIF3E,MVD,PSMC3,HRAS,SEC23A,ARL4D,RPL35A,RPS16,ARF6,G6PD,CAV1,NAA11,STX6,ATP1B1,RPL24,TAF9 |
| 9.650e-09 | -18.46 | DNA Replication | REACTOME pathways | R-HSA-69306 | 109 | 63 | 10285 | 3229 |
RPS27A,PSMD4,PRIM2,MCM3,RFC4,CCNA2,PCNA,PSMC3,PSMA1,PSMB9,FZR1,SEM1,RFC3,ORC6,PSME2,RPA3,RFC5,PSMD6,PSMB4,PSMB2,PSMD1,PSMA6,FEN1,CDC7,POLE4,PSMD12,PSMC1,POLA2,GINS3,MCM8,CDKN1A,UBA52,UBB,PSMD14,RB1,GMNN,POLE3,PSMD7,PSMD10,PSME1,GINS4,PSMA2,MCM6,PSMB6,POLD2,PSMB3,RPA2,MCM4,PSMA4,PSMC5,PSMB11,PSMA5,PSMB10,PSMA3,PSMB5,CDKN1B,ORC5,PSMC4,RFC2,PSMD3,PSMB7,POLD4,PSMB1 |
| 9.700e-09 | -18.45 | LEMD3 (LEM domain containing 3) | protein interactions | 23592 | 261 | 116 | 19454 | 5460 |
LAMP2,RAB5C,RB1CC1,SMAD9,POU5F1,RHOG,GJA1,SPINT2,RAB35,ARL11,EGLN3,DIRAS3,NUP35,HNRNPL,RHOH,DNAJC25,RND3,PLD3,SKA3,RPN1,STIM1,PTRH2,RAB4A,CYP2C9,TMT1A,SAR1B,KRAS,G3BP1,ARL5B,MTG2,RAB11A,PYCARD,DBH,FIS1,LMNB1,RMDN3,SEC61B,S1PR4,LMBR1L,IREB2,ESR2,MAD2L2,ACTB,REEP4,SYNE4,SEC62,OTULINL,RND2,FAM234A,CLDN4,BET1,SDC2,RABAC1,SDHAF4,RAB5A,NUP50,CXCR4,TSPAN15,STX7,PXMP2,B9D2,LAMP3,SLC25A46,ADIPOR2,STYK1,ESYT1,HSD17B11,RAC2,ARL4D,SMAD3,PTPN1,ARL10,TMPO,STX6,LMAN1,ARF6,DNAJC1,PRNP,SMAD1,FURIN,CTLA4,CBX3,OLA1,ARF4,FKBP8,H3C1,SRPRB,HNRNPK,RAB3B,RAB2A,MAT2A,SMAD2,SYNGR1,TMEM74,ZNF330,SMAD5,SEC63,VIRMA,COPE,RHOJ,CDC42,TMEM106A,ST7,ATG16L1,LMNA,RPA2,FGFR1,SSR1,GP9,PRKCB,RAB9A,DERL1,DVL2,RPA3,MME,LPAR1 |
| 9.753e-09 | -18.45 | TSR1 (TSR1 ribosome maturation factor) | protein interactions | 55720 | 309 | 133 | 19454 | 5460 |
RPSA,TP53,MRPL47,TBK1,DNAJC2,BMPR2,CBX3,ABCE1,HAPSTR1,MRPL52,PPP1R12A,VPS16,RIGI,MEPCE,RPS13,KPNA2,NOC4L,H3C1,CSNK2A1,COPS5,CIDEB,USP15,RPS2,SNRNP70,MRPL24,RBM42,TOP1,CGAS,RPS27L,MRPL50,RPS16,CAND1,DNAJC1,FZR1,SPPL3,RBMS2,POLR1D,RPS14,DYRK2,HSP90B1,GRM2,RPA2,LMNA,SQSTM1,PRPF4,SIRT7,PNO1,RPA3,BAP1,MRPL41,FBXW7,MRPL40,SMC4,RPS15,RPS17,SUB1,SMARCA5,UBE2H,RC3H2,BICD2,RPS20,RPS12,PHAX,GSK3A,ZNF330,TUBA1B,RPS3,PSPC1,DEK,YES1,RPS7,NUP153,RAF1,BUD23,CYB5B,RPS23,MOB3C,RPS11,SMNDC1,RPS24,DNAJB4,CCT8,RPL31,UBE2A,RPS4X,RUVBL1,DDRGK1,WWP2,IFI16,DRG1,MRPS26,PHB1,SRSF1,CEP19,SUMO2,LYAR,NOB1,RPS10,PAFAH1B1,H1-5,SYK,PIH1D1,UBAC2,EP300,RPS28,PYM1,G3BP2,STAU1,EEF1G,UFL1,EIF1B,TMEM177,RPS29,RIOK2,CUL3,HNRNPC,MYC,POLR1B,DNAJB6,RPS26,RPS5,FTSJ3,CCT2,PSKH1,RPS9,POLR3B,FAU,ESR2,RPL10,TNPO3,LAMTOR3,MATR3,USP16 |
| 9.848e-09 | -18.44 | USP5 (ubiquitin specific peptidase 5) | protein interactions | 8078 | 187 | 89 | 19454 | 5460 |
CAV1,UBTD2,UBP1,CD274,RAC2,RAP1B,OSBPL8,MOV10,COPS5,TRIM63,PSMA5,DUSP19,PSME1,TMEM31,RAD23B,TP53,YTHDF2,KBTBD4,URM1,TRIM54,TMOD3,SMURF1,OPTN,STUB1,GNPDA1,SGTA,TADA3,HERC4,UBE2H,XPOT,TUFM,AR,SIRT7,TXNDC17,PML,RPA3,DVL2,BAP1,SNAI2,KLF4,OXSR1,CCND1,TPT1,ATG16L1,SUMO2,RAB11B,CEP19,ZNF593,ATP6V1A,TRAF6,AGR2,IKBKB,TRIM8,WWP2,PRDX1,NT5C2,XPO1,HNRNPA1,TRIM26,G3BP1,PABPC1,PCNA,OTULIN,SMARCB1,E2F4,ISG15,TCEAL1,UBE2S,LMBR1L,FCER1G,FAS,NLRP3,THTPA,USP13,MYC,HMGCS1,YTHDF1,HSCB,UCHL3,RNF11,XRCC5,EP300,PSMA3,TRIM5,TXNL1,PIH1D1,PGRMC1,DUSP22,PPP1CB |
| 9.856e-09 | -18.44 | HSP90B1 (heat shock protein 90 beta family member 1) | protein interactions | 7184 | 550 | 215 | 19454 | 5460 |
MYL12A,TLR1,CDC5L,CAND1,CD274,COX4I1,CAMLG,CSNK2A1,COPS5,DPP4,FAM20C,EDEM1,COX5A,MEPCE,KDM4B,TOLLIP,CAPN2,FURIN,RNF8,TFCP2,DNAJC2,APOO,ACTR1A,H2AX,TP53,SUCLG2,CTSB,PHAX,UQCRC2,PSMA6,LIG3,ATP1A1,UBE2H,CALU,DNAJC10,H2BC9,SLC25A1,AKT1,PTPN11,MARS1,HSPA5,CLU,TLR2,DERL1,BAP1,PML,HEXIM1,UBE2M,PRKCA,CYC1,RPA2,TRIM68,GABRA1,CFTR,SPTBN1,SUMO2,CORO1C,EED,SWAP70,NKX3-1,AGR2,PPIB,CTNNB1,IFI16,PSMA1,KRAS,VDAC1,MYO1B,PDIA6,PTGFR,TUBB4B,PDHA1,MSX2,TOP3B,ESR2,STAT1,VDAC2,DLST,CKB,CCT2,H2AZ2,PSMD14,BTF3,OST4,MYC,SFN,UFL1,NDUFS2,RER1,STAU1,PHB2,ADRB2,HDAC5,AKAP1,DDX39B,TMEM106B,PIH1D1,GRIK1,PPT1,SEC62,NEK7,EDEM3,TOMM22,PAFAH1B1,MDM2,PRNP,LDLR,EFNA3,PSMD7,ESYT1,HDAC6,CALR,CDC37L1,ARF4,VWF,PRDX4,RIGI,PTGES3,ERLEC1,RNF115,HUWE1,DNAJC30,EMC2,IGF1R,HSD17B10,TLR4,PPP1R12A,TCOF1,PPME1,RNF181,HSPA13,NDUFS3,PHF23,UQCRQ,OGN,VIRMA,NDN,MGST3,GANAB,DNASE1L1,TRIM24,PTEN,CCNF,ENO1,CDC73,XPOT,LGALS8,TXNIP,TUFM,CTSD,CIAO1,MBD3,PDHB,FBXW7,SYVN1,SOD1,COX6C,GRM2,HSP90B1,METTL14,UQCRC1,BRINP1,ATG16L1,NDUFS8,CACYBP,OS9,DNAJB9,PHB1,AHSA1,RB1CC1,PDIA3,SAR1B,KIT,TRIM37,PCNA,NDUFA4,PLD3,EZH2,STIM1,RPN1,NGB,CHMP4C,FAF2,ASPM,ERLIN2,RAF1,B3GNT2,GPR37,TUBB,RMDN3,SEC61B,HSP90AA1,NTRK3,RIT1,BRCA1,DCAF4,TOMM40,MCM4,MCM3,ALDH1L1,AUH,CUL3,CUL2,PXMP2,UCHL3,BIRC2,TXNL1,PSMA3,HADHA,DNAJC3,SLC25A3,KLF3,DET1,H1-5,DAAM1 |
| 9.858e-09 | -18.43 | PSMD14 (proteasome 26S subunit, non-ATPase 14) | protein interactions | 10213 | 508 | 201 | 19454 | 5460 |
CCDC92,USP15,EDEM1,FZR1,SPPL3,TMEM31,NEFL,ACVR1,PSMC3,UBL4A,KBTBD4,INSIG2,HADH,PSMA5,TGFBR2,HNRNPK,MEPCE,H2BC14,FKBP8,PSME1,ABCE1,DHX9,TLR9,CCDC174,UBE2H,PSMB2,CEP85,H2BC9,BUB3,ADRM1,PSMA6,PSMC5,SGTA,RPA2,H2BC11,IPP,HEXIM1,SPTBN1,CFTR,PAAF1,STK38,HSPA5,BAP1,PML,IRF3,HNRNPH2,H2BC17,AGR2,HSPB1,GSTM3,STK4,DDRGK1,NT5C2,HNRNPL,MITF,TCP1,DYNC1I2,HSP90AB1,CCT7,PSME2,MAGED2,TUBB4B,PLS3,H2BC1,MOB3C,H1-3,TUBA1A,ISG15,PSMA2,KRAS,PSMA1,TOP2B,CCT8,RTCB,CCT2,PSMD14,PRSS1,H1-1,PSMA4,PSMD1,MLF2,PSMD4,PSMD6,POLR2B,PSMB6,PRMT5,SF3B4,ZMYM2,MAP2K1,EIF4B,PSMB3,YIPF5,NEK7,UFL1,ARHGEF39,EYA3,EEF1G,SVOP,DDI1,DDX39B,BMPR1A,HSPA8,RAB5A,DDX5,CD9,PSMD7,ID1,TOP1,CAV1,PSMB1,CAMK1,ILF2,RAD23B,CCDC47,CCT5,EEF1A1,PSMB9,DDX39A,CD2BP2,UBE2V1,SEM1,HUWE1,HSPE1,FARSA,PSEN1,RNF20,RAB1A,NLRP9,HSD17B10,CSK,ATP5F1A,USP14,AR,TXN,UBB,VIRMA,CCNF,STUB1,ENO1,TUBA1B,ODR4,MSN,ALB,LMNA,HSP90B1,GRM2,RARS1,TMOD1,PSMC4,UBA52,UBLCP1,TTR,RPL4,PFKFB2,RPA3,SOD1,SQSTM1,MAVS,H2BC12,PSMD10,PPM1B,RSBN1L,PSMD3,DPY30,MAP3K14,INA,EGLN3,DHX15,PSMB4,PSMB5,PCBP4,EZH2,RPN1,FAF2,KIT,INSYN2B,PSMD12,RPS27A,AHCYL1,SCYL2,HSPD1,UBE3A,BAG2,BRCA1,YWHAZ,HSP90AA1,RIT1,ALDH1L1,PRPF31,TUBB,SPINDOC,ACTB,TAB1,PSMB7,H1-5,WDR77,RNF11,PSMC1,TXNL1,NMRAL1,PSMA3 |
| 1.005e-08 | -18.42 | VWA8 (von Willebrand factor A domain containing 8) | protein interactions | 23078 | 332 | 141 | 19454 | 5460 |
VIRMA,ACAT1,MRPS28,UBE2H,OAT,MRPS16,TUFM,PYCR2,NDUFAF2,POLDIP2,MRPL20,GRPEL1,MRPL40,MRPL41,PDHB,NME4,GFM1,DERL1,SQSTM1,DLAT,TWNK,GID8,TRIM10,AMACR,MTRES1,SCLT1,QRSL1,NUDT12,MRPS34,RPA2,NTPCR,NDUFAB1,MRPL10,MRPS23,MALSU1,MRPL50,SPPL3,COX4I1,MGME1,MRPS9,SSBP1,AIFM1,NXT2,TMEM70,GRSF1,ABHD10,FASTKD5,MRPS18C,RASL10B,HSPE1,MRPS33,PDE12,MRPS18B,ATP5PF,MRPL49,GFM2,NDUFS3,BCS1L,METTL15,PPIF,AURKAIP1,HADH,MRPL11,MRPL47,NDUFA2,ATP5PB,NDUFAF4,ESR2,MRPL23,ATP5F1B,MRPL13,CCDC90B,MTG1,DLST,S100A6,TACO1,IRF2,HTRA2,MRPS25,FAM83A,MRM2,PMPCA,CUL3,PYCR1,AUH,MTG2,MRPS7,NT5C3A,MRPL57,NDUFS2,HSCB,HADHA,EXD2,NGRN,LCA5,NDUFA5,UBAC2,ATP5PO,MRPL12,NDUFAF3,PRDX3,RMND1,EGLN3,NDUFS8,GATD3,FAHD1,PHB1,ARMC8,RPL23,CDC23,MRPS26,RHOG,NDUFV2,HSPB8,MRPL9,MRPS35,FAM174A,STOML2,MTRF1,CLPX,IMMP2L,MRPS17,KGD4,ETFA,COX8A,HECTD3,TRIM21,HINT2,HSPD1,NDUFA12,SMARCB1,PDHA1,NDUFS6,SCHIP1,LGR4,ERLIN2,FAF2,ETFB,HSDL2,TOP3B,RAF1 |
| 1.008e-08 | -18.41 | CAPRIN1 (cell cycle associated protein 1) | protein interactions | 4076 | 428 | 174 | 19454 | 5460 |
RPL17,MEPCE,SRPRB,DHX9,RPL3,ABCE1,RNF8,NUPR1,DNAJC2,ACTR1A,DUSP1,RPSA,CDK4,RPS27L,CAND1,RPS16,FZR1,RPL32,CD274,SYNCRIP,RPL10A,RPS2,SNRNP70,RPL24,COPS5,ENY2,MARS1,EIF4E,RPS15,RNF113A,LSM12,PML,RPL27,BAP1,DNAJC24,HEXIM1,UBE2M,SSR1,RPA2,DAPK1,SEC61A1,SRP54,EIF2S2,CCSER2,RPS3,PSPC1,UBE2H,IGF2BP1,PKNOX1,RC3H2,SPOP,EIF3G,RPS17,RPL7A,RPS4X,PTPN4,KRAS,TOP2B,PABPC1,LSM14A,RPL31,RPS23,RPL18,MTA2,RPS7,SOX2,TRMT1L,TOP3B,LYAR,RPS10,FUBP3,DUSP6,CTNNB1,DDRGK1,RPL6,WWP2,IFI16,STAU1,UFL1,FXR2,RPS28,PYM1,RFC4,PIH1D1,NUFIP2,DNAJC27,FBXO42,RPL27A,RPL10,DNAJB6,CDKL2,RPS26,H1-10,CIRBP,BTF3,MYC,MSH6,EIF3E,RPS13,RPL23A,PPP1R12A,SRP72,PPP4C,YTHDF2,FBP1,RPL35A,LDLR,SRPRA,HDAC6,GRSF1,RPL4,NUCKS1,NF2,MTDH,SIRT7,RPA3,DVL2,RPLP0,RARS1,GRM2,RPS14,VIRMA,RPL22,DEK,SEC63,RPL13A,RPS20,RPS12,EIF2AK2,METAP2,OPTN,CCNF,MAPRE1,USP14,AHCYL1,DHX16,G3BP1,RPS24,ZC3H7A,TENT5D,RPS11,CHMP4C,EZH2,RPL29,RAF1,B3GNT2,RPL7,RPLP1,RPLP2,TSG101,PHB1,RPL8,RPL9,RPL23,HNRNPA1,ATG9A,PIK3R1,G3BP2,GPC1,YTHDF1,LARP4B,WDR77,RPL19,PRRC2A,RBBP4,RPL35,RPS9,RPL37A,EIF3K,LSM14B,ILK,RPS5,BRCA1,CUL3 |
| 1.011e-08 | -18.41 | RMDN3 (regulator of microtubule dynamics 3) | protein interactions | 55177 | 312 | 134 | 19454 | 5460 |
HSCB,UFL1,EMC1,GPM6A,ARMCX2,PEBP1,UPF3B,EXD2,HSPA8,AKAP1,TMEM203,EMP3,VAPB,ARMCX3,FAM3C,TOMM22,TOR1AIP2,OTULINL,SEC62,DUSP22,TAX1BP1,CHCHD3,ESR2,ATP6AP2,LMBR1L,SEC61B,YWHAZ,SCFD1,CCDC25,FIS1,TMEM100,VEZT,CYB561D2,TOMM40,EMC8,USP30,HNRNPDL,SCYL2,TMEM147,STIM1,RPN1,UCK2,CRELD1,OTULIN,CSTPP1,STBD1,RAF1,CSNK1E,MACO1,FAF2,KIF2A,OCRL,SLMAP,EGLN3,CIB3,ATP6V1A,STX5,AGR2,HNRNPD,C2CD2L,YWHAB,PDIA3,RAB5C,MARCHF5,YWHAH,INSYN1,YWHAG,DDRGK1,YKT6,SLC7A1,PFKFB2,TOMM20,HSPA5,TMEM209,TEX264,MAVS,TMEM243,HSP90B1,PDCL,LEMD3,RABL3,SEC22B,DAPK3,RPGRIP1L,VIRMA,SEC63,VAMP3,OPTN,PLP1,MOB4,GANAB,CISD1,NRP1,FGFR1OP2,C9orf72,CCNB1,FOXA3,CSGALNACT2,GORASP2,SLC7A14,TF,SRPRB,PSEN1,FKBP8,MDC1,ABHD10,NSDHL,EGFL8,HINT1,EMC2,TFRC,SNAP29,TOR3A,PREB,CCDC47,INSIG2,MTCH2,FAM162A,LBR,NRM,PRNP,LMAN1,ZBTB2,PTPN1,SRPRA,EHBP1,CAMLG,RAC2,CDCA3,ESYT1,USP15,FNDC11,SLC25A46,EMC4 |
| 1.015e-08 | -18.41 | MRPL9 (mitochondrial ribosomal protein L9) | protein interactions | 65005 | 206 | 96 | 19454 | 5460 |
SCFD1,H1-1,MRPS25,MRPL16,AUH,MTG2,MYC,PMPCA,RPL19,RPL10,MRPL23,RPL35,MRPL13,ZNF22,FAU,TACO1,MTG1,SLC25A3,MRPS18A,APOBEC3C,MRPL12,RPL27A,CA12,TMEM177,HSCB,SAT1,MRPL34,NGRN,EXD2,MRPS26,POU5F1,RHOG,MRPL18,HNRNPA1,MTRF1,RPL6,FAHD1,GATD3,RPL18,EZH2,SOX2,RANBP1,SRSF4,MRPS17,H1-6,FAM76B,HINT2,SRSF7,UBE3A,HSPD1,UBE2H,RPL26,TUFM,CIAO1,EIF4H,RPL13A,GANAB,MRPL53,MTRES1,JUP,PLP2,MRPL10,RBMS2,MRPL20,MRPL17,MRPL40,MRPL41,GFM1,SNRNP70,CHCHD1,TMEM70,MALSU1,MRPL24,CAND1,MRPL50,PRR3,SSBP1,ALYREF,KRR1,GFM2,MRPL33,MRPL51,MRPL49,APOBEC3D,AURKAIP1,METTL15,MRPL11,MRPL47,MRPL22,FASTKD5,MEPCE,RPL17,HNRNPK,RPL23A,MRPL52,SLC25A10 |
| 1.027e-08 | -18.39 | SUMO4 (small ubiquitin like modifier 4) | protein interactions | 387082 | 85 | 49 | 19454 | 5460 |
CFTR,PRDX3,GSTP1,LMNA,PRDX6,PGK1,TXNL1,HSPA8,IDH3A,FOS,HSPA5,PITHD1,GMPS,LDHB,ACO2,LMNB1,CCT2,SF3B4,ENO2,NFKBIA,ENO1,PAFAH1B3,CCNF,STAT1,ATP5F1B,PRDX2,UBE2V1,JUN,CCT5,RPSA,IDH1,PDIA6,HSPD1,PRPS1,PRDX4,VDAC1,HNRNPF,GAPDH,TPM3,STOML2,CALR,PDIA3,HNRNPD,SPINT2,MTAP,PHB1,G6PD,CCT7,HNRNPL |
| 1.074e-08 | -18.35 | CLTC (clathrin heavy chain) | protein interactions | 1213 | 611 | 235 | 19454 | 5460 |
AR,PPP1CC,TUFM,FBXO7,RUNX1,SEC13,CIAO1,MAPRE1,CDC73,AP2A1,EPHA2,PIP4K2C,ZBTB18,OPTN,CCNF,CEP97,VIRMA,UQCRQ,TECR,RHOJ,ARHGAP1,ATG16L1,STAMBP,CHMP1A,HSP90B1,PICALM,STOM,GRM2,JUP,SQSTM1,EGFL7,PRKCB,SIRT7,RHOU,RPA3,FBXW7,HMGB1,GTF2I,SNAP91,HDAC6,SLC25A46,DNAJC7,TES,SEC23A,LDLR,MYBL2,NLRP1,TFE3,CAV1,CDK9,PRNP,ARF6,DCUN1D1,MAP1LC3B,CCDC47,PPME1,IGF1R,EHD4,PRDX4,TOM1,HUWE1,MCM3,CUL2,RAB11A,PKP4,CUL3,RIT1,MYO6,YWHAZ,BRCA1,RHOB,ATP1A3,FAM83A,AP2M1,BTG3,MAD2L2,RANBP6,DET1,RND2,EHD1,NCALD,SLC25A3,ARMCX3,ARL6,PYGB,UCHL3,CYFIP2,HNRNPA1,DCAF11,HAX1,RHOG,MAP1LC3A,GJA1,PHB1,DNM2,CACYBP,CCAR2,SPTAN1,OCRL,LGR4,DSTYK,PPP2R1A,ACTN4,ACO1,B3GNT2,CSNK1E,RAF1,POLR2C,RPN1,VPS33A,EZH2,UBE3A,BAG2,HNRNPA2B1,SCYL2,TRIM37,TNF,LASP1,KIT,ST13,AKT1,SNX5,UBE2H,ATP1A1,RC3H2,CISD1,PPP2R5E,UQCRC2,SRC,DYRK1A,SMURF1,ADRM1,KCTD9,CFTR,CDC42,SPTBN1,CYC1,UBE2M,HEXIM1,RPA2,BAP1,HSPA5,ABCC2,GAPDH,EDC3,COPS5,EDEM1,ATP6V1D,SHC1,CHCHD1,RAC2,SSBP1,TMPO,FCHO2,CAND1,VTI1B,RPSA,MTCH2,TP53,RRM1,UBL4A,RNF8,NUPR1,CAPZA2,NECAP1,TFRC,TFCP2,CBX3,PIK3CA,TRAFD1,POC1B,CAPZA1,MEPCE,TOLLIP,ATP1A2,CHMP1B,NEDD8,BTF3,SFN,MYC,ZMPSTE24,FBXW11,LAMTOR1,FAM83B,DLST,LMBR1L,VDAC2,TOM1L1,SNRNP40,TOM1L2,MTF1,TOMM22,CNDP2,PIH1D1,CSNK1A1,KLC2,PPT1,MAP2K1,PAK2,EP300,HDAC5,HSPA8,BMPR1A,DDX39B,ADRB2,PHB2,SSR3,STAU1,UFL1,DDRGK1,YWHAG,WWP2,YWHAB,STAMBPL1,AGR2,IKBKB,EED,RHOH,SUMO2,HNRNPL,RPS10,AFTPH,EEF2,ISG15,CRTC2,DHX38,MOB3C,HGS,RHOBTB1,RND3,PDHA1,PTRH2,RPAP3,VDAC1,KRAS |
| 1.089e-08 | -18.34 | Disorders of transmembrane transporters | REACTOME pathways | R-HSA-5619115 | 76 | 48 | 10285 | 3229 |
PSMB1,OS9,PSMB7,PSMD3,PSMC4,ERLEC1,PSMA3,PSMB5,PSMB10,PSMA5,PSMC5,PSMB11,PSMA4,PSMB3,PSMB6,PSMA2,PSME1,PSMD10,KCNJ11,SFTPD,PSMD7,AVPR1B,RNF5,DERL2,PSMD14,UBB,UBA52,DERL1,SFTPA1,CFTR,PSMC1,PSMD12,ERLIN1,PSMA6,PSMD1,PSMB2,PSMB4,SFTPC,ALB,PSMD6,PSME2,SEM1,PSMB9,PSMA1,PSMC3,ERLIN2,PSMD4,RPS27A |
| 1.092e-08 | -18.33 | MAP3K14 (mitogen-activated protein kinase kinase kinase 14) | protein interactions | 9020 | 166 | 81 | 19454 | 5460 |
YTHDF2,TRMT1L,RPL15,TIMM8A,TRAF2,EEF1A1,RBM34,RPL18,ALPL,RPS11,PPAN,SLC25A10,SLC25A5,RPS24,BAG2,RPL3,TMEM33,TRIM63,HNRNPF,RPL28,RPS13,RPL6,MOV10,MAP3K14,TRAF6,RPL24,IKBKB,RPL10A,RPL23,AKAP8L,RPL32,TIMM8B,RPL8,RPL9,RPLP1,RWDD1,MAGED2,RPL7,RPS27L,NOB1,RPL35A,HSP90AB1,SURF6,EEF1E1,TANK,TIMM13,SLC25A3,ANXA7,IRF3,PEBP1,RPL27,MTDH,HSPA8,BIRC2,RPL4,FXR2,UNC45A,RPL7A,GRB10,SLC25A1,SAMHD1,OTUD7B,BRCA1,H1-10,PSMD14,PELI3,DNAJB6,HSP90AA1,RPS26,NFKBIA,RPL37A,PRKRA,PRMT5,RPL13A,RPL10L,SLC25A4,RPL10,RPL19,TRAF1,TECR,POLR2B |
| 1.107e-08 | -18.32 | HTRA4 (HtrA serine peptidase 4) | protein interactions | 203100 | 182 | 87 | 19454 | 5460 |
PIAS1,SEPTIN6,HNRNPH2,GFM1,ARPC2,CDK1,OXSR1,HNRNPH3,CPSF4,CAPN1,GTF3C4,PPP1R10,DYRK1A,PDCD5,EIF4A3,PSMA6,TUBA1B,PSMC5,GTF2A1,DNAJC10,CDC73,MTPN,DNAJC8,PPP1CC,EIF3E,DAP,SELENOF,CAPN2,MRPL49,TAF2,RPSA,TP53,TMSB10,RPL35A,EIF2B5,CDK9,WDCP,MRPS9,RPL12,EIF4E2,UBE2N,CDK12,RPL10A,PPIL4,TPM3,API5,PSMC1,DNAJC3,DDX39B,TXNL1,USP39,GTF2IRD1,ANXA7,PSMB3,PPP1CB,ACTB,TUBB,S100A6,TACO1,PARP2,PELO,SF3B4,ADK,COX6B1,NIBAN2,MRM2,HNRNPAB,MCM4,MCM6,PSMD12,CBLL1,TPD52,RPL29,NUP153,PPP2R1A,ACTN4,TCP1,GLRX,CCT7,PSMB4,SELENOM,CYB5A,PDCD10,TGFB3,CBL,RAB5C,MRPL9 |
| 1.107e-08 | -18.32 | NDUFS4 (NADH:ubiquinone oxidoreductase subunit S4) | protein interactions | 4724 | 182 | 87 | 19454 | 5460 |
DNAJC30,FASTKD5,ATP5PB,NDUFA2,IL1R2,MRPL11,DDX39A,AURKAIP1,METTL15,NDUFS3,GFM2,GPR34,SSBP1,SDHB,UBE2G2,NDUFB4,COX4I1,FUT1,NDUFA1,GRSF1,TMEM70,RPS2,NDUFC2,DLAT,GFM1,SLC25A51,TOMM20,CRYZ,RPS14,COX6C,MTRES1,CYC1,UQCRC2,STUM,TMEM74,MGST3,NDUFB10,ATP5F1A,TUFM,SYP,ATP1A1,DNAJC19,HSPD1,NDUFB5,SLC25A5,NDUFA4,HINT2,VDAC1,IMMP2L,YIPF3,NDUFS6,AQP3,CRELD1,NDUFA12,FUBP3,CYB5A,GATD3,NDUFS8,UQCRH,MTRF1,NDUFV2,CTNNB1,RHOG,MRPS26,NDUFB8,RPL23,NGRN,EXD2,EMP3,NDUFS2,HSCB,ARMCX2,NDUFAF3,VAPB,ATP5PO,VDAC2,TACO1,LMBR1L,CCDC90B,MTG1,CHCHD3,PARL,MTG2,COX6B1,NDUFB7,AUH,PMPCA |
| 1.108e-08 | -18.32 | SNRPB2 (small nuclear ribonucleoprotein polypeptide B2) | protein interactions | 6629 | 242 | 109 | 19454 | 5460 |
DHX9,ZC3H11A,THRAP3,LSM4,CDC40,SNRPG,SMN1,MEPCE,FBP1,H2AX,WBP11,CD2BP2,GABPB1,DDX42,CAMK1,NUPR1,ALYREF,RCHY1,UBE2N,NAP1L5,CDC5L,CWC15,RBM17,COPS5,SNRNP70,PRPF4,DDX46,RPA3,CWF19L1,RBM22,FBXW7,EIF5B,SNRPN,SF3A1,CDK7,METTL14,IDH2,GRM2,RPA2,WTAP,EIF4A3,SF3B6,CCNF,PTEN,TRIM27,PHAX,SUGP1,DNAJC8,TRIM23,SPOP,UBE2H,HNRNPA2B1,HSPD1,EWSR1,PICK1,ZBTB14,CCAR1,MCM6,E2F4,RAF1,SOX2,SMNDC1,PLS3,EZH2,SNRPE,SART3,SF3B5,IFIT2,SRSF1,SNRPD3,SNRPA1,DHX15,WWP2,PDIA3,DDRGK1,ZNF207,HNRNPA1,XPO1,PSMD10,DDX23,SKIC8,POU5F1,SNRPA,DDX39B,SLU7,EP300,SF3B1,HSPA8,CMTM6,SAP18,COIL,MRPL12,USP39,CSNK1A1,MFAP1,PNMA1,SNRPD1,SF3B4,SNRPD2,SNRNP40,ERH,RPL10,ESR2,HNRNPC,CUL3,MYC,SNRPB,TTC33,PRPF31 |
| 1.108e-08 | -18.32 | PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) | protein interactions | 5048 | 242 | 109 | 19454 | 5460 |
ISG15,PPP2R1A,TUBA1A,ANAPC13,NUDCD3,RPL18,RPS11,SKA3,TUBB4B,PDIA6,SDHC,HSPD1,SAR1B,RPL28,PSMD12,ETFA,KRAS,YWHAG,YWHAH,PDIA3,MPHOSPH6,ARMC8,YWHAB,SOSTDC1,TNIK,KCTD10,DYNC1I2,PAFAH1B1,BET1,TANK,RPL27A,NDE1,ISOC1,ACAA2,PAK2,HADHA,PAFAH1B2,PCCB,PDE4B,PYCR1,MYC,RIT1,HSP90AA1,H1-10,YWHAZ,RPS9,DYNLRB2,SNRPD2,VPS72,FAU,ACTB,DYNLL1,FNTB,CENPM,RPSA,FURIN,CAPN2,DISC1,RPL3,TCOF1,MAP1B,SNRPG,RPS13,TOLLIP,DYNC1I1,CSNK2A1,HDAC6,KARS1,CHID1,RPL12,MAPRE2,RPS16,CCND1,PSMC4,RPS14,PCK2,ZNF574,HSP90B1,CDK1,DCTN4,SQSTM1,GID8,BAP1,CHMP2B,RPL4,TUFM,FBXO7,RPL26,ATP5F1A,CIAO1,RPL7A,MAPRE1,ZFAND6,BICD2,SPOP,RPS12,ACAT1,MSN,PSMC5,GANAB,PAFAH1B3,RPS3,STUB1,CCSER2,RPL22,DYNLT3,SUCLG2,GRPEL2,RPL13A |
| 1.113e-08 | -18.31 | positive regulation of response to external stimulus | biological process | GO:0032103 | 564 | 228 | 18204 | 5365 |
PQBP1,TRIM3,IRAK4,OSM,CCL1,ZNRF1,SETD4,STK24,PTGER4,CXCL13,NTRK3,IFI16,TLR8,IKBKB,IL34,TRIM15,TLR1,TPBG,TICAM1,IL15,ATAT1,BMPR2,IL23A,VEGFA,SRC,FGFR1,IL18,RAC2,NONO,NECTIN2,PIK3CG,TLR4,HEXIM1,PHB2,TOMM70,IDO1,CTSC,IFNG,IL17F,CXCL8,LPAR1,CD47,TIAM1,F7,NEK7,PDCD4,P2RY12,CLEC7A,IL21,TLR2,RARRES2,NLRP3,TRAF6,MIR222,TLR10,TICAM2,PRKCA,THBD,TBK1,PLSCR1,XRCC5,MAPKAPK3,NINJ1,TMEM126A,AIF1,TLR5,CCL19,CCR2,F2,TIFA,TMSB4X,PDE2A,MAP2K6,TASL,CXCL10,LSM14A,PSPC1,CGAS,ALOX5AP,NPY5R,CASP4,KCNJ8,CXCL12,OTULIN,CD1D,SYK,FGF16,HMGB1,NLRP1,FEM1A,MBL2,CCR4,CREB3,AGER,PYCARD,PLG,STAP1,TRIM5,CD226,EMILIN1,CXCR4,S100A8,CX3CL1,SMAD3,XCL1,CAMK2N1,TNF,TRIM62,VAMP7,PHB1,TRIM6,LY96,KLRC2,PIK3AP1,CX3CR1,MGST2,MYD88,SH2D1A,TLR9,IFNK,IFIH1,RTN4,MIR21,PTN,FABP4,CD81,LILRA2,CLEC6A,TAB1,MAVS,NMI,TYROBP,RIGI,SIN3A,CAV1,IFNB1,MSTN,CASP12,SWAP70,OPTN,POLR3F,FKBP1B,CD28,CD36,HSPD1,BCL10,LDLR,DDT,HTR2A,IL12A,SCG2,CD274,MATR3,MIF,CCL3,PELI1,RNF34,FLOT1,VEGFC,OXSR1,IL6ST,USP15,IRF3,HSP90AA1,TLR3,POLR3B,DEFB124,UBE2K,IL12B,CCL5,GPSM3,NUPR1,HSPB1,MIR142,IL6,RSAD2,MIR126,IGF1R,CD14,MIR206,CCL21,MET,KLRD1,CNR1,BECN1,IFI35,MIR221,PAK2,IL2,NRP1,TIRAP,PLA2G5,IRF7,TLR7,NLRP6,DEFB114,FCGR1A,OAS1,TRAF3IP3,LTA,LACC1,PRKCE,CCR1,VAMP8,DHX9,IL1B,PTPN22,CREBBP,ITGA2,NCR3,SEMA5A,CCR6,KLK3,CCR7,CDH13,TLR6,CLPB,FCN2,CALR,MIR144,KARS1,NFKBIA,EP300,CCL24,KLK5,TNFAIP3,FGF10,HYAL2 |
| 1.123e-08 | -18.30 | AURKB (aurora kinase B) | protein interactions | 9212 | 743 | 278 | 19454 | 5460 |
RPL15,ACCS,NDUFS3,MRPL49,MSRB3,PPP1R12A,HSD17B10,RPL23A,MDC1,PRDX4,MSH6,PTGES3,ARF4,RPS13,MOV10,NFKB1,KLHL9,CDC42SE2,PSMD7,RPL12,AIFM1,HACD3,H2AZ1,RB1,MAPRE2,DCUN1D1,ZBTB2,MDM2,SEC22B,MYL12B,RPS14,FTH1,CNP,HSP90B1,LMNA,MRPS34,RPLP0,RPL26L1,RPA3,SQSTM1,RPL4,FBXW7,BRIX1,POLDIP2,MBD3,PYCR2,SEC13,TUFM,USP14,PPP1CC,RACGAP1,AR,ATP5F1A,RPL26,MAPRE1,CDC73,CCNF,RPS20,UBE2I,RPS12,UBASH3B,GANAB,RPL13A,TMOD3,RPL22,UBB,TECR,RAF1,TPBG,PPP2R1A,RPL29,CHMP4C,SKA3,SART3,RPS11,HNRNPA2B1,PPAN,MAEA,HSPD1,SKA1,BAG2,RPS24,SRSF7,G3BP1,FLOT1,PSMD12,GTF3C3,MAP1S,NDC80,PSMD3,HSPB8,HNRNPA1,PPM1B,DICER1,HAX1,PHB1,RPL8,RPL9,RPLP1,RPLP2,PLEKHO2,RPL7,AGK,SNX2,NOP58,DHX15,NUF2,STK3,PPIA,CACYBP,EGLN3,ATP5PO,USP39,NDUFA5,MYL6,ATP5MK,NUBP2,PSMA3,NMRAL1,NOP53,UCHL3,G3BP2,SKP1,CUL3,RPS29,MRPL16,RIT1,HSP90AA1,RPS5,RPS9,TUBB,RPL35,MRPL23,RPL19,ERH,TP53,SURF4,CBX3,NUPR1,TBC1D4,PSMC3,BIRC5,HBP1,SLC25A11,MAP1B,DHX9,RPL3,CLPB,SCML1,HNRNPK,H3C1,PSMA5,RPL17,DUSP19,COX5A,TPM3,ROGDI,SMCHD1,H2AC4,TUBG1,RPL10A,RPS2,RPL32,SSBP1,AIP,ITK,SYNCRIP,RPS16,FMOD,FZR1,SURF6,CDC5L,ILVBL,MBD5,MRPL10,RPA2,HECTD1,CYC1,BANF1,DDX46,RPL27,HNRNPH2,MRPL41,RPS15,HSPA5,GRPEL1,RPL7A,SLC25A1,UTS2,RPS17,RC3H2,DNAJC10,SPOP,CALU,DTL,ATP1A1,RPS3,RPL10L,CDC20,TRMT1L,CBLN4,RPS7,TUBA1A,PNMA2,H2BC1,NIM1K,RPS23,RPL18,CCT8,PABPC1,RPL31,FBXO3,MYO1B,RUVBL2,RPAP3,RUVBL1,TCF23,HNRNPF,KRAS,TFG,RPS4X,RPL6,TSPAN10,DDX50,QPCTL,STK4,CTNNB1,YWHAH,XPO1,YWHAG,AK2,HSPB1,DDX1,TNNC2,DUSP6,SIN3A,S100A8,CORO1C,PABPC1L,TCP1,LYAR,RPS10,LANCL1,HSP90AB1,CCT7,RAMP3,RPL27A,PABPC5,PIH1D1,NUFIP2,XRCC5,AKAP1,EP300,DDX5,SF3B1,HDAC5,STAU1,PAPOLA,MYC,BAG3,RALGAPA2,FTSJ3,PSMD14,CCT2,THTPA,LMBR1L,EIF4EBP3,PHKB,SF3B4,PCMTD1,TAX1BP1,TIMM21,ATP5F1B,MATR3,RPL10,DES,NCKAP1,CBX5 |
| 1.127e-08 | -18.30 | Rrbp1 (ribosome binding protein 1) | protein interactions | 81910 | 220 | 101 | 19454 | 5460 |
DDX1,DRG1,RPL23,CNOT2,RIOX2,RPL6,HMG20A,MEAF6,FAM98A,EIF2S1,NOB1,NOP58,LYAR,RPL7,RPL9,RPL8,MRTO4,RPS11,EIF1AX,RPL18,RPS23,GTPBP1,TRMT1L,RPS27A,RPS4X,RFC3,G3BP1,ZC3H7A,RPS24,RTCB,ABCF1,RBM3,TOP2B,RPS5,GTPBP2,H1-10,RFC5,RPS29,RPL10,RPL19,RPL35,LRRC1,RPS9,FAU,TRMT112,PACSIN3,EEF1G,EMG1,RFC4,PYM1,RPS2,RPL10A,TOPBP1,RPL24,MPG,ERCC3,RPL35A,IFRD2,RPS16,SEMA3C,RPS27L,EEF1B2,SRP14,RPL12,RPL32,SRP72,EEF1A1,RPL15,RPSA,RPS13,EIF3E,RPL17,NOC4L,RPL23A,RPL3,NKRF,RPS17,PPP1CC,SMARCA5,RPL7A,RPL22,ZNF622,RPP25L,RPL13A,EIF2S2,RTRAF,RPS12,RPS20,RPS3,CCNF,EIF2AK2,RPLP0,RPS14,BRIX1,TMUB1,WDR3,RPS15,NPM3,RPL4,RPL27,PNO1 |
| 1.130e-08 | -18.30 | negative regulation of blood vessel endothelial cell migration | biological process | GO:0043537 | 82 | 49 | 18204 | 5365 |
MIR129-1,MIR16-1,HDAC5,MEF2C,MIR424,MIR29C,MIR137,ATP2B4,MIR200C,MECP2,MIR204,MIRLET7B,MIR212,PPARG,MIR503,MIR221,MIR149,MIR492,MIR146A,MIR497,CSNK2B,MIR320A,MIR20A,MIR193A,RGCC,GADD45A,MIR206,JUP,MIR15A,MIR188,SPRED1,MIR505,PDCD10,TNF,MIR133B,MIR640,MIR101-1,MIR24-1,MIR152,KLF4,MIR10A,MIR361,VASH1,HMGB1,MIR495,MIR205,MIR885,STARD13,MIR132 |
| 1.158e-08 | -18.27 | TRIP4 (thyroid hormone receptor interactor 4) | protein interactions | 9325 | 201 | 94 | 19454 | 5460 |
DHX9,RPL23A,RPL3,RPS13,THRAP3,HUWE1,MLLT6,EEF1A1,DDX39A,MRPL11,SYNCRIP,SMAD3,DBT,CGAS,FZR1,RPS16,RPL35A,NFKB1,RPL10A,RPS2,MED27,SQSTM1,NOG,SOD1,RPL4,XBP1,CAPN1,ATG16L1,RPS14,PAX9,RPL26L1,JUP,RPS20,GTF2A1,EIF2AK2,RPS3,RPL10L,AR,ATP5F1A,RPL7A,RAB2A,EIF3G,ASCC1,EWSR1,RUVBL2,RPL28,RPS4X,ROCK2,RUVBL1,KIF2A,TULP3,JUN,RAF1,RPL18,RPS11,RPL8,DHX15,RPL7,TCP1,RPS10,DDRGK1,XPO1,RPL6,RPL23,MED4,DDX1,DDX5,HADHA,EP300,SF3B1,HSPA8,DDX39B,G3BP2,CSRP1,MCMBP,STAU1,MED11,ALKBH3,RPL27A,INPP5E,CNDP2,NUFIP2,LARP4B,MED23,PPARG,PRMT5,ESR2,CBX5,MED17,RPL35,CREBBP,PFDN2,DCAF4,MED10 |
| 1.174e-08 | -18.26 | RASIP1 (Ras interacting protein 1) | protein interactions | 54922 | 20 | 18 | 19454 | 5460 |
HNRNPD,CFL1,CDC42,RACGAP1,BAG3,FGFR1OP2,ARFGAP1,RAP1A,RNF41,BUB3,PPP1R18,LDB2,RRAS2,MRAS,RAP2A,HRAS,CD274,SIKE1 |
| 1.178e-08 | -18.26 | SNAP receptor activity | molecular function | GO:0005484 | 37 | 28 | 18094 | 5411 |
SEC22B,GOSR2,USE1,STX6,SEC22A,VAMP3,STX8,STX16,VAMP7,STX11,STX7,VAMP2,STX18,SNAP29,YKT6,BET1L,STX1A,VTI1B,BET1,GOSR1,STX17,STX5,STX10,VAMP1,SNAP23,VAMP8,SNAP25,STX12 |
| 1.179e-08 | -18.26 | organic substance catabolic process | biological process | GO:1901575 | 1644 | 585 | 18204 | 5365 |
COMT,UGT1A1,TRIP4,CNOT8,HSPA8,ADORA1,CHMP1B,CRBN,HUWE1,SMG9,ENC1,DDIT3,SORD,FBXL7,HMOX2,ENO2,MDM2,HSD17B11,CDC26,CTSC,HADHA,TP53,PYGM,IDO1,PSMB5,FBXL14,CNP,UBE2D3,ANAPC16,NCBP2,DDX5,VPS4A,FHIT,DCP2,CDO1,COP1,PDE9A,HECTD1,UFD1,KLHL22,GNPDA1,RNF20,NQO1,CHMP5,SESN2,RNF187,CHMP4C,ACOX1,LIPA,SLC16A1,CYP7A1,APOBEC3H,SGTA,NUDT7,LYG2,CSNK1A1,HINT1,UBE2H,GNPDA2,CUL2,CBR3,RNF139,LSM6,CLN8,SIAH1,CNOT7,APOC2,RBCK1,CYP27B1,GAPDH,PNPLA4,FBXO22,GABARAPL1,FAF1,YTHDF2,PSMB9,EDEM3,UPF3B,PCYOX1L,HEXB,AASDHPPT,ABHD17A,STUB1,DDAH1,FEM1A,DNAJC10,CYP4F12,CYP3A5,DFFA,MME,PSMD4,BCKDK,CDK5,NSFL1C,VPS28,SH3BGRL,HECW1,RNF5,PSMD3,ADIPOQ,APPBP2,GALC,PLAAT3,SHMT1,PPT1,TMUB1,GID4,FBXO31,DBH,TRAF2,TMEM106B,ERLEC1,PDE12,ETF1,PSMA2,MTHFS,RNF144B,DIS3L,RAD23B,EDEM2,AMT,FUT8,CASC3,ACOT8,PYGB,FBXO3,RNF133,CAPN1,TRIR,PSMD14,CTSD,ATG3,APOBEC3B,DCTD,HSP90B1,SH3GLB1,MPST,FBXW11,OGG1,NUDT3,ECHDC1,TNFAIP1,GGT7,APOBEC3D,YWHAH,CYP26A1,SLC6A7,HERC3,OAT,HTR2A,HSP90AA1,ACADSB,PDE7A,FBXO8,UBE2A,GDE1,CYP2F1,WDR45,RNF34,FITM2,WWP2,CDC16,NUDT18,ALDH1L1,IER3,ANAPC4,ZER1,SAT1,RCHY1,FBXO11,APOBEC3G,AUH,AGO1,PLA2G4B,CDC20,ABHD10,FZR1,FAF2,HSPA5,CYP2D6,PSMB10,NUDT5,ZMPSTE24,SPOP,HTRA2,KLHL3,ABHD12,WWP1,IDE,UBE2I,APOBEC3F,NUDT1,MTM1,PSEN1,PLPP6,TRIM26,GALE,MOXD1,ACHE,CRAT,RC3H2,LDAH,SMG5,DCTPP1,BLVRA,CMA1,ERLIN1,RNF7,PLCXD3,SMPD2,LYPLAL1,NEU1,KCTD17,ANAPC15,OXCT1,SLC25A17,PDE8A,GDPD3,DBR1,LDHA,PLA2G15,SPP1,FEM1B,PEX13,SDF2L1,FMO1,HSD11B1,PGAM1,AMACR,FAM8A1,ISG15,RNF8,VPS4B,SULT1A3,RNF167,ADTRP,SLC6A3,STBD1,UCHL3,DCAF11,PDE1A,TMUB2,DPEP1,RBM7,KLHL15,ZFAND2A,NEDD8,RLIM,RNF11,PAOX,CPT1B,ACADS,LSM2,OTUD7B,CPT2,FBXL4,EXOSC4,CBL,NDFIP1,PLA2G12A,FEN1,BAG3,PSMB1,DICER1,TST,ZCCHC7,TOPORS,BECN1,UBXN10,CNOT6,CYP1A1,DNAJB9,PYM1,USP14,EDEM1,PGPEP1,PRPF19,OS9,GAD2,DNPH1,PELO,ILVBL,CTSB,ANAPC11,HGS,STPG4,RNF126,SLC25A21,RB1CC1,EXT1,XPNPEP1,PSMB4,UTP25,ANKIB1,AIG1,PLCB2,CHDH,SQSTM1,LEP,RNF41,POLR2G,TRIM21,PDE4B,NUDT4,SPOPL,RNF146,DTL,FBXL3,PAFAH1B1,TENT2,RNF121,APEX1,CDC23,GPIHBP1,LYPLA2,PGM1,CACUL1,TRIM45,DBT,CYP39A1,MAGOHB,ZFAND2B,DECR2,DLST,ADRM1,KLF1,CUL3,CCDC47,ZNRF1,MAN1A2,RNF148,FAH,TRIM3,BSCL2,PSMD1,CAPN2,AREL1,PGK1,METTL14,FBXO44,CRYM,MGAT1,SNX17,HNMT,FBXO7,NFE2L2,PDE1B,ABHD2,ETFB,EIF3E,FGF23,NUDT16,TMEM199,LYPLA1,EXOSC3,SPSB3,CCAR1,SMUG1,BNIP3L,PPM1K,RNF115,EDC3,SAMHD1,GK2,BFAR,PSMC1,CLU,SDS,ANAPC13,UBL4A,DERL2,RNASEH1,HDAC6,HSD17B6,PRDX6,FBXW7,PSMA1,APOBEC3C,SARM1,UBAP1,NT5C2,MCAT,KCTD10,ABHD16B,PNRC1,GLUL,EIF4A3,UBE2L3,HNRNPD,TRIM32,CNOT6L,PSMC4,BIRC2,KBTBD6,ELOC,APOBEC3A,NUDT12,CD2AP,CYP1B1,NAE1,USE1,ENTPD4,CCNF,MYLIP,VPS54,URAD,RNF10,RNF40,BPGM,ACAT1,RNF26,PSMC5,CHI3L1,DISC1,MRTO4,FBXW4,CLPX,RMND5B,HINT2,NUDT9,PDE2A,PML,SLC25A44,ARG2,FUT9,RNASET2,UBXN2B,PABPC1,PNP,OVGP1,PPP2CB,RNF122,HECTD3,PSMA6,FUT1,DHPS,LDLR,ENO1,SULT1B1,PAFAH1B2,KLHL25,GPD2,TENT4A,PELI1,CHAC2,CYP27A1,THRAP3,MAGEC2,ERLIN2,UBE3A,RNF14,UBE2K,ABHD4,SUCLG2,RNASE6,LAMP2,ABHD6,TOM1L1,HEXA,ENPP4,USP38,CRMP1,CHMP1A,UBB,PSMB7,LSM5,ACAA2,SMURF1,PCK2,PLCB1,ABCC2,RHOBTB3,TKTL1,OGDHL,UBE2B,MTAP,MGST2,MAEA,SMG8,PSMB11,ANAPC2,PAFAH1B3,WDR82,ENPEP,HM13,DNAJC3,HADH,MMP20,UBE2S,PSMB2,ECRG4,SRD5A3,DNAJB2,JKAMP,ETFA,IFI27,PSMB6,CHMP2A,PHYH,ENTPD3,PNPLA8,CHMP2B,EXOSC1,PMAIP1,ASRGL1,NUDT19,BAP1,DXO,TP53INP2,UBE2G2,HERC4,RNASEH2C,SIAH2,ESD,AKT1,UBA52,PCCB,RPS27A,EXOSC8,DNASE1L1,RNF128,LSM4,FKRP,PFKFB2,SELENOS,UBXN6,GPC1,ISG20,DDI1,PPP1R11,DIO3,UCP2,FEM1C,MAGOH,UBE2W,CNOT2,SNX5,RNF103,PSMD6,SKIC8,GK5,HSD17B10,ARMC8,CALR,PSMA4,FBXO9,WDR77,CRYL1,PSMA5,PSMD12,GRSF1,GID8,HYAL2,CTSK,IAH1,TNFAIP3,CTNNB1,GPT,TOLLIP,XBP1,EHHADH,SEC61B,PSMB3,SPSB1,SLCO1B3,SLCO2B1,PLAA,PSMC3,SKP1,TRIM24,UBE2D1,UBE2N,TSG101,FBXL19,PLA2G5,PCSK9,GSK3A,PPP1R8,ACER3,PSMA3,SYVN1,PSMD7,AKR1A1,BAD,DERL1 |
| 1.182e-08 | -18.25 | Regulation of mitotic cell cycle | REACTOME pathways | R-HSA-453276 | 87 | 53 | 10285 | 3229 |
PTTG1,ANAPC4,PSMB9,FZR1,SEM1,PSMD6,ANAPC2,ANAPC15,PSMB4,CDC23,UBE2D1,PSME2,PSMD4,CCNA2,ANAPC11,RPS27A,PSMA1,PSMC3,PSMD12,CCNB1,PSMC1,ANAPC16,MAD2L1,PSMA6,PSMB2,PSMD1,PSMD7,SKP1,CDK1,PSME1,PSMD10,UBB,UBA52,CDC26,PSMD14,PSMC4,NEK2,PSMA3,PSMB5,CDC20,PSMB1,PSMD3,CDC16,PSMB7,PSMB3,PSMB6,PSMA2,BUB3,PSMB11,PSMC5,PSMA5,PSMB10,PSMA4 |
| 1.182e-08 | -18.25 | APC/C-mediated degradation of cell cycle proteins | REACTOME pathways | R-HSA-174143 | 87 | 53 | 10285 | 3229 |
PSMA2,PSMB6,BUB3,PSMB3,PSMA4,PSMC5,PSMB11,PSMA5,PSMB10,PSMA3,PSMB5,NEK2,PSMC4,CDC16,PSMD3,PSMB7,CDC20,PSMB1,CDC26,UBA52,UBB,PSMD14,PSMD7,PSMD10,CDK1,SKP1,PSME1,PSMB2,PSMD1,PSMA6,MAD2L1,ANAPC16,CCNB1,PSMD12,PSMC1,RPS27A,PSMD4,CCNA2,ANAPC11,PSMC3,PSMA1,FZR1,PSMB9,SEM1,PTTG1,ANAPC4,UBE2D1,PSME2,PSMD6,ANAPC2,PSMB4,CDC23,ANAPC15 |
| 1.198e-08 | -18.24 | PURA (purine rich element binding protein A) | protein interactions | 5813 | 259 | 115 | 19454 | 5460 |
RPL3,RPL23A,MEPCE,MIRLET7C,MIR16-2,RPL17,RPSA,MIR200C,RPL15,MIR17,LLPH,MIR106B,HRAS,KRR1,PRR3,RB1,MIR25,CAND1,FZR1,MIRLET7G,PRNP,CGAS,MIR429,MYL12A,SURF6,H2AC4,SNRNP70,MIR34A,MIR205,MIRLET7I,MIR34C,MTDH,DGCR8,RPL4,FBXW7,NHP2,MIR34B,ATG16L1,RBMS2,DYRK2,RPLP0,MIR21,MIR7-1,RPS3,EIF2AK2,PRKRA,FGFBP1,PTEN,RPL13A,SRPK2,CSK,RC3H2,PDCD4,UBE2H,RPL31,SCYL2,MIR9-2,RPAP3,CDK5,G3BP1,MIR155,SRSF4,RFC3,RFC2,RAF1,ZNF263,B3GNT2,ARFGEF1,OTUD6B,MIR222,H1-3,MIR7-2,HNRNPL,RPS10,CCAR2,LYAR,IFI16,MIR143,MIR29C,YWHAH,CPEB1,HNRNPA1,YWHAG,DDRGK1,DDX23,MIR31,POU5F1,MIR1-1,MIR221,MIR140,EP300,CYFIP2,POLA2,PSMC1,H1-5,SYK,PPP1CB,SURF2,MIRLET7B,RPL35,MIRLET7D,MAD2L2,RPL19,NCKAP1,MYC,CUL3,RAB11A,ZNF668,MCM3,PSKH1,ZCRB1,ICAM1,MIR363,SP1,H1-1 |
| 1.214e-08 | -18.23 | H3C6 (H3 clustered histone 6) | protein interactions | 8353 | 223 | 102 | 19454 | 5460 |
MCM4,MCM3,SMARCE1,RPL39,PRPF31,RCL1,ICAM1,RPS26,PRMT5,SNRPD2,RPL37A,RAN,PARP2,RPL19,PRRC2A,ERH,CBX5,SPINDOC,RPL35,RBBP4,PSMD4,ACTL6A,WDR77,RPL27A,EIF4B,H2AC1,CCDC86,SF3B1,RPS28,XRCC5,HIRA,PPM1B,HMG20A,SPTAN1,SNRPA1,SNRPD3,RPS10,HNRNPL,RPS7,RPL29,SF3B5,MTA2,PDHA1,SRSF7,TRIM21,PCNA,PABPC1,RPL31,HSPD1,SSRP1,RAD21,MCM6,RPS27A,CCAR1,ASF1A,RBBP7,RPS17,RPL26,RPL7A,MAT2A,STK38L,YPEL5,RPS20,TRIM24,RPS12,MACROH2A1,MRPS28,TMOD3,BUB3,SF3A1,RPS14,SPTBN1,LMNA,PRPF4,NBN,CSTB,RPL27,HSPA5,MBD3,PFKFB2,STK38,GTF2I,CD81,RBM17,H2AC4,SNRNP70,RPL24,RPL32,SSBP1,CWC15,SLAIN2,TMPO,TOP1,UBR7,EEF1A1,MTA3,CBX3,TCOF1,RPL17,PHF1,THRAP3,HNRNPK |
| 1.241e-08 | -18.20 | MRPL16 (mitochondrial ribosomal protein L16) | protein interactions | 54948 | 177 | 85 | 19454 | 5460 |
RPL23A,RPL3,HINT2,MRPL52,HSPD1,RPL31,RPL17,SRSF4,MRPL22,MRPL11,MRPL47,MARCKSL1,MRPL51,RPL18,RHOBTB1,FURIN,RND3,NDUFS3,FAHD1,GATD3,RAC2,PRR3,RPL9,COQ8A,MALSU1,MRPL50,RHOH,DDRGK1,HNRNPA1,CD81,MRPL9,MTRF1,SNRNP70,RHOG,MRPL18,GFM1,EXD2,SNX11,AMACR,RHOU,NGRN,RPA3,MRPS7,MRPL40,FBXW7,MRPL41,TMEM177,HSCB,MRPL12,ELK4,RBMS2,CDC42,MRPL10,RND2,RPL27A,MTRES1,MFAP1,EPHX1,MRPS18A,RPA2,MRPL13,MTG1,MRPL53,TACO1,RPL10,RPL19,RHOJ,RPL35,RPL13A,MRPL23,TUFM,RPL26,PSMD1,ATP5F1A,PMPCA,MRM2,MYC,AUH,MTG2,MRPS25,RC3H2,RHOB,ARHGAP19,TAFAZZIN,SPOP |
| 1.265e-08 | -18.19 | POLR2C (RNA polymerase II subunit C) | protein interactions | 5432 | 333 | 141 | 19454 | 5460 |
PRMT5,GPN2,INTS10,POLR3B,GTF2F1,POLR2F,RPS9,GTF2F2,NFKBIA,LRIF1,POLR2B,ESR2,TENT5C,MED17,SNRPB,LMO2,MYC,CUL3,PFDN2,RIT1,POLR1B,HTRA2,CCT2,MED10,FAS,BRCA1,GPHN,NMRAL1,MED13L,SNRPA,PSMC1,HSCB,MED11,WDR77,TOMM22,NUP62,MED31,PIH1D1,DNM2,RPRD1A,POLR2L,EGLN3,DHX15,CCT7,RPL7,TCP1,XPO1,EIF3D,BAZ1B,RAB5C,WWP2,MED4,DRG1,ELP6,FKBP4,RUVBL2,RPAP3,FAM76B,BAG2,FAM168A,CCT8,FGF3,RPL28,SSRP1,IMMP2L,KRAS,SOX2,GTF2E2,MED9,SUPT5H,MTA2,POLR2C,RBPJ,POLR2D,RHOBTB1,NUDT19,CHMP4C,INTS12,POLR3H,CCNF,OPTN,STUB1,SMURF1,CEP97,SRC,PRKACB,PPP1CC,RSPH1,ATF4,MED22,CDC73,CCHCR1,ELOF1,TCEA1,SOD1,POLR1H,MED30,CDC42,POLR1D,PSMC4,ATG16L1,UBE2W,VPS54,HAUS2,RPRD1B,WWP1,ZNF326,GTF2B,CDK9,TOP1,POLR2I,COPS5,ERCC3,RPS2,CLP1,MAP4,MED27,MED21,MED29,ERG28,ABCE1,SLC25A11,PDRG1,RNF20,MDC1,EIF3E,SEM1,PSMA5,FARSA,DNAAF10,DDX39A,PSMB9,RPAP2,EEF1A1,RPL15,TBK1,TP53,CCT5,POLR2G,TAB2,CDK8 |
| 1.267e-08 | -18.18 | LARP1 (La ribonucleoprotein 1, translational regulator) | protein interactions | 23367 | 438 | 177 | 19454 | 5460 |
NDN,VIRMA,CCNF,OPTN,METAP2,GANAB,RPS12,RPS20,PIP4K2C,IVNS1ABP,MAPRE1,RPL26,AR,PPP1CC,DGCR8,FBXW7,HMGB1,AATF,RPA3,SIRT7,RPLP0,RPS14,ATG16L1,SIPA1L1,RBMS2,TOP1,CDK9,EIF4E2,KRR1,PRR3,PSMD7,CALR,NFKB1,MOV10,HDAC6,WASL,RPS13,EIF3E,SLC25A10,HAPSTR1,ILF2,SRP72,APOBEC3D,TSN,RPL35,EIF3K,RPS9,PSKH1,YWHAZ,BRCA1,ZCRB1,RPS5,CUL2,CUL3,MCM3,RPS29,MCMBP,G3BP2,RTKN,LARP4B,WDR77,PPP1CB,SPTAN1,WDR44,DHX15,PHB1,TSG101,PSMD10,RB1CC1,HNRNPD,BCL2L1,HNRNPA1,TRA2A,G3BP1,SRSF4,PPAN,SRSF7,TESK2,EZH2,CHMP4C,RPS11,NLRP2,SART3,RAF1,PPP2R1A,RPL29,ADRM1,RPS3,PSPC1,PSMA6,FGFBP1,RC3H2,ELAVL2,UBE2H,ST13,BAP1,PML,RNF113A,RPA2,DYRK2,KLF4,SPTBN1,FGF13,FZR1,RPS16,CAND1,KCTD3,RBM42,SNRNP70,RPS2,NOL12,MAP4,EDEM1,CSNK2A1,COPS5,H3C1,MEPCE,RPL17,SNIP1,PSME1,HBP1,NAA35,STRBP,RPSA,DUSP1,MATR3,TAX1BP1,RPL10,CMTR1,SURF2,PSMD14,H1-1,MYC,HNRNPC,SFN,BTF3,UFL1,STAU1,HSPA8,EP300,STK26,KLC2,EIF4B,CSNK1A1,PIH1D1,PABPC5,SYK,ELK4,NEK7,HNRNPL,RPS10,PAIP1,SRSF1,AGR2,DRG1,YWHAB,CNOT2,IFI16,RPL6,WWP2,YWHAG,CPEB1,YWHAH,DDRGK1,HNRNPF,NUP42,RPS4X,HNRNPDL,TFG,RPL31,PABPC1,RPAP3,PLS3,GLE1,MOB3C,SOX2,PAIP2B |
| 1.276e-08 | -18.18 | NDUFB9 (NADH:ubiquinone oxidoreductase subunit B9) | protein interactions | 4715 | 130 | 67 | 19454 | 5460 |
NDUFB5,RAB1A,NDUFA4,COX7B,RIGI,PRPS1,DNAJC30,VDAC1,YIPF3,APOO,ATP5PB,MTCH2,NDUFA2,E2F4,NDUFA12,CRELD1,GPR34,RPN1,NDUFS3,NDUFS6,CORO1C,FUT1,CYB5A,FAHD1,NDUFA1,SDHB,FEZ1,PHB1,COX4I1,MYL12A,ATP5PD,NDUFS8,NUP35,NDUFV2,KLHL22,ETFRF1,COX5A,NDUFB8,POR,TACR1,NDUFC2,MEF2A,ABCC2,EMC1,PHB2,FBXW7,UQCRC1,TIMMDC1,MPV17,NDUFA5,COX6C,ATP5PO,VAPB,STOM,MRPS28,UQCRC2,VDAC2,PARL,ATP5F1B,ACTB,LAMTOR3,CSGALNACT2,MTG2,NDUFAF2,NDUFB7,NDUFB10,LMNB1 |
| 1.282e-08 | -18.17 | defense response | biological process | GO:0006952 | 1431 | 516 | 18204 | 5365 |
TRIM5,APOBEC3C,S100A8,FCGR2B,CCL23,OTULIN,CD40,RAB14,WDR83,NLRP1,CCR4,SYK,CLU,CH25H,YES1,TFRC,LACRT,SELENOK,TMIGD3,TRIM62,ASIC1,TRIM32,CRHBP,GPAM,TUSC2,KLRC2,DEFB115,RNASE9,ATG16L1,SARM1,IFIT2,CD2,LGALS8,NINJ1,STAT5A,ADGRE2,BPGM,TBK1,XRCC5,VAMP3,P2RY11,TLR5,CCL19,SFTPD,VPS54,DPP4,TICAM2,NDP,TLR10,TLR2,RARRES2,TRAF6,CD2AP,SNAP23,APOBEC3A,ALOX5AP,CCL4L1,PLP1,NFKB1,DRD1,KCNJ8,RNASET2,ARG2,TUBB,PML,FOS,PSPC1,CCL2,CHI3L1,SEMG2,BMPR1B,IL2RA,TASL,RNASE4,FASLG,CD40LG,TRIM21,MIR140,TFEB,REG1B,PIK3CG,CD58,HEXIM1,COTL1,PHB2,ZNF175,TRIM35,NT5C3A,SRC,IL18,CHST1,EXT1,PRDX1,PNMA1,LGR4,TMEM45B,CAMP,PRKRA,TAB2,IFNG,FAU,SERINC3,CD47,IL17F,ACTR2,CTNNBIP1,BPIFB1,TLR8,NDUFAF4,IFI16,OPRK1,AFAP1L2,CCL1,PQBP1,IRF1,SETD4,CUL3,TRIM10,NR2E1,SAMHD1,TIMP1,BNIP3L,LYZ,SEMA7A,LILRA1,IL23A,MIRLET7I,MECP2,MIR181C,NFE2L2,TICAM1,TLR1,ISG20,FKRP,TANK,AGR2,TLR6,NCR3,IFNA13,IL1B,AKT1,CEBPE,ZMYND11,DEFB129,CXCL11,CCL24,TMEM106A,HYAL2,TNFAIP3,SLC1A1,FBXO9,UBE2W,PPP1R11,CERS6,EP300,ROMO1,KLRD1,UBE2N,MIR221,MIRLET7B,PLAA,KIT,IL22,TUBB4B,CD14,EIF2AK2,ODAM,TOLLIP,RPL13A,CDC42EP2,RAB27A,DEFB114,ACER3,LACC1,TIRAP,BST2,USP46,B4GALT1,ACP5,STAT1,JAK2,STXBP1,LYZL6,BCL2L1,RPL39,DAPK3,CXCL14,IFNGR1,NEUROD2,MIR130B,VDAC1,MATR3,TMED1,MX1,FOXP3,TRIM34,VPS26B,CAMLG,PYDC2,IFNA10,IL6,NDST1,SERPINA1,RSAD2,TRAF3IP2,PI3,RTP4,EIF4E,IL12B,TREML1,DDX1,FCER1G,MX2,RNASE6,FGR,RNASEL,POLR3B,G3BP2,MIR223,MACIR,RAB23,CXCL9,CXCL3,DNAJC3,IFNA2,AQP4,LILRA2,DHX16,JAK1,SH2D1A,EXOC1,SYNCRIP,LEAP2,WFDC5,TLR9,IFNK,ATG7,TNFRSF1B,CDC42EP4,CD36,HP,OPTN,PMAIP1,POLR3F,TXNIP,NMI,CLEC6A,SIN3A,RIGI,TSPAN18,IFI27,LYAR,BATF,IL1RAP,AGER,PYCARD,HRAS,CXCR4,OR2H2,H2BC1,PLAC8,BCL6,CXCL12,EPHA2,MBL2,CD1D,HMGB1,PHB1,LY96,TRIM6,PDE12,VAMP7,TRAF2,CX3CR1,NMBR,FCGR2A,IL10,XCL1,PTGFR,RBPJ,CX3CL1,RAF1,TNF,CCR3,DEFB121,PLSCR1,AIF1,ABCF1,IRF4,TIFA,F2,CCR2,POMT2,ACVR1,CEBPG,CCL25,NLRP3,CHST2,CXCR3,TRIM23,CITED1,NLRP2,CGAS,MRGPRX1,GNG7,CASP4,PTGER1,CCL18,NKIRAS2,APOBEC3B,LSM14A,CXCL10,VAMP2,TNFRSF14,IFI6,TLR4,TRIM27,SEC14L1,NONO,CCL8,KLF4,LXN,CCL11,BPIFA2,LARGE1,ADORA3,ADORA1,PRDX2,UGT1A1,MIR26B,COMT,TMEM33,MSMP,IL13,H2BC12,ENDOD1,AZI2,IL21,CLEC7A,TNFAIP6,TP53,SPAG11B,IDO1,TAC1,CXCL8,LYZL4,FADS2,BRINP1,APOBEC3H,LYG2,PTGER4,PPARG,SLC15A2,FCMR,CXCL13,LIPA,IRAK4,PRKCQ,TNFAIP8L2,CDO1,TRIM52,F11R,NQO1,PLGRKT,DROSHA,ATAT1,ITK,YTHDF2,SDHAF4,CNOT7,TRIM15,GAPDH,CYP27B1,IKBKB,IL34,RBCK1,EPO,SERPINA3,LGALS3,HCFC2,CXCL1,JCHAIN,CCL20,CST11,WFDC13,STAT6,DDIT4,ISG15,FOLR2,CCR7,UAP1,CCR6,TTC4,C1QC,VAMP8,DHX9,NFKBIB,CXCR6,IRF2,JAGN1,TRIM8,NCK1,LIAS,TF,DEFB116,DEFB1,MAP2K3,IL1A,FCN2,CLPB,CD209,POLB,PLD3,DPEP1,SRPK2,NOTCH2,ATP1A2,ATP1B1,BECN1,IFI35,STAT2,FAM3A,CCR5,OLR1,MIR20A,CYBC1,CCL21,PRCP,HNRNPA0,EXOSC4,DHRS7B,TRIM22,CCDC92,OAS1,FCGR1A,REG1A,CCR1,MRC1,HDAC5,CHGA,SHC1,IRF8,LTA,FOSL2,MAP3K14,DHX15,TRIM29,H2BC11,NLRP6,TLR7,IRF7,USP14,IL5,SMAD1,AKAP1,TNFSF8,IRF3,STX8,PELI3,MOV10,ELMOD2,RPS6KA4,LILRB1,BCL10,SCG2,IL12A,APOBEC3D,MIF,BPIFB3,CD83,CCL3,NUPR1,APOBEC3G,CDC42,DAPK1,PLA2G4B,IFNAR1,PTGER2,CCL17,TRIM68,TLR3,DEFB124,G3BP1,CNPY3,CCL5,CST3,PSEN1,MIR146A,NLRP9,CD4,TRIM26,PTN,PLPP6,CLDN1,CD46,RNASE1,APOBEC3F,IL4,TACR1,MYD88,SLPI,IL20RB,IRF9,IFIH1,POLR3H,MSRB1,RAB1A,TAX1BP1,ZYX,HTR1A,MAVS,TYROBP,TRIM11,IFNB1,CHID1,NCR3LG1 |
| 1.284e-08 | -18.17 | RICTOR (RPTOR independent companion of MTOR complex 2) | protein interactions | 253260 | 747 | 279 | 19454 | 5460 |
TFPT,NSDHL,HSD17B10,IGF1R,PC,ZC3H11A,RPL23A,HSPE1,THRAP3,CMPK1,BLOC1S3,EEF1A1,LBR,DDX39A,TRAPPC13,EEF1AKMT3,AIFM1,RPL12,HRAS,ARF6,PLGRKT,G6PD,CAV1,AKAP17A,CALR,STYK1,IDH3A,RPA3,PPM1G,RHOU,PRKCB,RPL4,FBXW7,SMC4,GTF2I,PDHB,UBA52,FUT8,SEC22B,SF3A1,WDR5B,ATG16L1,RPS14,HSP90B1,LMNA,JUP,RARS1,SH3GLB2,ENO1,CIB2,TMSB4X,CTTN,TUBA1B,CCNF,ALB,MSN,GSK3A,RHOJ,TMOD3,LDHA,VIRMA,CIAO1,CYRIA,CDC16,CTSD,TUFM,ATP5F1A,RPL26,STK24,CA2,AP2A1,XPOT,HNRNPA2B1,HSPD1,SLC25A5,BAG2,RBBP7,FLOT1,PCGF6,IMMP2L,MCM6,NAA15,ERLIN2,FAF2,ACTN4,GFPT1,EZH2,RPN1,SART3,RPS11,PHB1,BRD9,KRT8,GJA1,RPL7,KIF3B,DHX15,DIRAS3,CACYBP,EGLN3,UBXN6,PRDX1,PSMD3,CLPX,PDIA3,HSPB8,CSTA,RHOG,RPL23,AHSA1,HNRNPD,CCDC86,HADHA,UNC45A,ASB3,AZGP1,FBXO30,PYGB,STX7,H1-5,PRR5L,RND2,SLC25A3,MYL6,PELO,ARF1,GNG12,SEC61B,RBBP4,TUBB,GNB1,CUL3,GRB10,ZNF250,MCM4,RHOB,BRCA1,MYO6,YWHAZ,ILK,NTRK3,HSP90AA1,RPS5,SLC25A11,MAP1B,DHX9,IDH1,GALNT12,RPL3,HNRNPK,CRYBA4,SRPRB,NEDD8,PSMA5,FKBP8,TKTL1,RDH11,TMSB10,ACTR1A,IK,GPD2,TFRC,ACSL4,SSBP1,GATAD1,AKR1B1,RAC2,CAND1,SPPL3,CDC5L,LMAN1,STX6,TMPO,RBM17,TPM3,GAPDH,GNG2,CSNK2A1,ZNF473,LANCL2,SMAD4,TUBG1,SLITRK5,MAP4,NBN,TRIM10,DDX46,PRDX6,STK38,HSPA5,SPTBN1,CD2AP,CDC42,IDH2,RPA2,WRAP53,PARD6A,PRKCA,UBE2M,GCFC2,B4GALT1,SRP54,CTSB,RAPGEF5,RPL7A,RAB2A,AKT1,TNFAIP3,DNAJC5,ST13,TIA1,CFL1,CHRAC1,DNAJC10,IGF2BP1,ATP1A1,CCT8,ABCF1,S100B,RUVBL2,RUVBL1,KRAS,PSMA1,RPL28,ARFGEF1,TRMT1L,CSTF2T,EEF2,TUBA1A,PNMA2,TUBB4B,RHOBTB1,DCUN1D5,RND3,SRSF1,RAB35,EED,TRIR,TCP1,RHOH,DYNC1I2,HSP90AB1,CCT7,TRMT61A,RAB5C,RPL6,YWHAH,XPO1,YWHAG,AGR2,IKBKB,HSPB1,ARMC8,YWHAB,UBFD1,STK26,EP300,HSPA8,SF3B1,P4HA2,TRIM52,ZC3H14,DHRS4,CTBP1,PIH1D1,CRYBB3,VDAC2,LORICRIN,SMU1,TAGLN2,STAT1,ESR2,EFNA5,PSMB6,SFN,LDHB,MYC,CCT2,LAMTOR1 |
| 1.304e-08 | -18.15 | STRBP (spermatid perinuclear RNA binding protein) | protein interactions | 55342 | 226 | 103 | 19454 | 5460 |
MEAF6,HNRNPL,MIR9-1,EED,MIR214,MIR141,HOMER3,MIR1-1,MIR221,HNRNPD,DICER1,MIR31,HNRNPA1,MIR29C,CPEB1,DDRGK1,MIR143,MRPS17,ROCK2,ASF1A,MIR155,MRPS11,RPS24,RPL31,PPAN,VPS33A,CHMP4C,RAF1,APEX1,RPL19,ESR2,SNRNP40,HTRA2,MRPS25,MIR98,MYC,HNRNPC,CUL3,MIR106A,STAU1,EP300,NGRN,FKBP10,APOBEC3C,LARP4B,PABPC5,BET1,MIR429,MRPS23,DCUN1D1,CAND1,RPS16,CXCL9,MIRLET7G,PRR3,SEC23A,MRPS9,KPNA1,MIR34A,MAP4,SNRNP70,H2AC4,COPS5,MIRLET7C,MEPCE,MIR16-2,NEDD8,CAMK2G,MRPS18B,DHX9,MIR9-3,MIR200A,ILF2,LLPH,APOBEC3D,MIR200C,AURKAIP1,THAP1,KLK6,PRKRA,FGFBP1,RPS3,EIF2AK2,ELAVL2,IGF2BP1,UBE2H,MIR145,MIR29A,UTP23,MIR7-3,RNASE1,SQSTM1,MIR34C,RPA3,SIRT7,MIR7-1,MRPS34,RPA2,MIR1-2,CCL3,CFTR,RBMS2,MIR34B |
| 1.360e-08 | -18.11 | STUB1 (STIP1 homology and U-box containing protein 1) | protein interactions | 10273 | 573 | 222 | 19454 | 5460 |
UBE2D3,UFL1,DDX39B,AKAP1,P4HA2,HSPA8,CSNK1A1,PACRG,FBXO42,PAFAH1B1,TCAP,PSMD4,ATP6AP2,APEX1,ESR2,IREB2,SRXN1,ANAPC2,PRMT5,PSMD14,LAMTOR1,PELI3,DNAJB6,PSMA4,MYC,MLF2,BAG3,PSMD1,ATG101,VDAC1,CDK5,STMN2,ADCY3,GHR,SPG21,TRAF2,DYNC1I2,MITF,PCSK9,PGR,ADCK1,CCT7,HSP90AB1,KCND2,HSPB1,POU5F1,POGK,UBE2E2,MAPK4,CTNNB1,HSPA5,EIF4E,BAP1,SMG5,TRIM68,RPA2,UBE2M,PAQR3,UBE2W,SPTBN1,CFTR,CDC42,AGO1,ADRM1,DAPK1,MKKS,SRC,TFEB,SMURF1,ATL1,TSSK1B,UBE2E3,TLR9,UBE2H,ZBTB38,ABCG2,IGF2BP1,OLFM3,MLF1,PSMB2,AKT1,SLC6A4,DNAJC5,KHDC1,KPNA2,DYNC1I1,KDM4B,STRADB,BACE1,ACVR1,CAPN2,CDK4,MTCH2,TP53,MIF,FZR1,MARCHF4,CAND1,LMAN1,UBE2N,CD4,CEBPG,POLB,TUBG1,SMAD4,AQP2,RBFOX3,DNAJB2,EDEM1,CSNK2A1,COIL,PXMP2,SNRK,TERT,PSMA3,NUBP2,PMAIP1,TMEM185A,NMRAL1,BIRC2,PPARG,CDKN1A,DET1,ACTB,USP5,GPR37,UBE2V2,S100A6,FOXP3,NLRP3,ILK,HSP90AA1,CUL3,ALDH1L1,TOMM40,MAP3K21,IRF1,RNF40,CDK20,AHCYL1,MAP3K11,HSPD1,BAG2,JAK1,SKA3,EZH2,POLR2C,TPD52,RAF1,IFNGR1,PPP2R1A,MPP1,CACYBP,EGLN3,PHB1,TRAF6,UBE2D1,PPP3CA,NQO1,HNRNPD,HAX1,DYRK1B,PRPF19,CRIP1,HNRNPA1,HMGB1,RPA3,SOD1,SQSTM1,FLCN,METTL14,SNAI2,GRM2,MET,UBA52,LDHA,SMAD5,UBB,SH3BGRL,UBE2L3,ENO1,GUCY1B1,STUB1,CCNF,ACAT1,PTEN,STK11,XPOT,SMAD2,CCL28,AR,BRAP,FBXO7,RUNX1,SEM1,PTGES3,RIGI,RNF20,OLA1,TLR4,FAF1,ACTR2,JOSD1,RAD23B,CCT5,TRIM6,SMAD1,UBE2V1,TOP1,DCUN1D1,ARF6,G6PD,RCHY1,SMAD3,SEC23A,UBXN10,DNAJC7,CDC37L1,BMPR1B,MOV10,NFKB1,HDAC6 |
| 1.363e-08 | -18.11 | PDHB (pyruvate dehydrogenase E1 subunit beta) | protein interactions | 5162 | 299 | 129 | 19454 | 5460 |
UBE2H,NDUFB10,AKT1,ATP5F1A,USP14,HMOX2,TUFM,MGST3,STAT5A,RHOJ,UQCRQ,CCNF,UQCRC2,RPA2,COX6C,HSP90B1,METTL14,DYRK2,UBE2M,HECTD1,MTRES1,CYC1,ATG16L1,UQCRC1,CCNH,PDHB,HSPA5,RPA3,BAP1,GID4,PML,DLAT,GFM1,POR,CALR,EMC4,COX5A,HDAC6,CAND1,SPPL3,FZR1,MIF,MYL12A,SSBP1,COX4I1,RAP1B,LDLR,TFCP2,NDUFS3,CAPZA2,SLC25A24,RPSA,MTCH2,MRPL11,EEF1A1,METTL15,UBR7,HUWE1,TRIM63,FASTKD5,MDC1,MAP1B,EMC2,HSD17B10,RHOB,LSM14B,AUH,MTG2,MYC,PMPCA,CUL3,CFAP20,TOMM40,MCM3,ATP5F1B,TENT5C,ACTB,ESR2,TACO1,MTG1,DLST,SNRPD1,KCTD12,ARMCX3,PPT1,NDUFA5,ANXA7,TOMM22,CDKN1A,PRCP,NDUFS2,HSCB,STAU1,ADRB2,PHB2,EXD2,HSPA8,NMRAL1,RAB5A,HADHA,RHOG,CBL,MRPS26,PPP3CA,ARMC8,MTRF1,NDUFV2,NDUFS8,UQCRH,EGLN3,WDR44,PHB1,CORO1C,ATP6V1A,GATD3,EZH2,NDUFS6,PDHA1,RAF1,E2F4,EEF2,RRAGB,EMC8,VDAC1,PFDN1,AKT2,NDUFA4,HINT2,COX8A |
| 1.365e-08 | -18.11 | CDK5RAP3 (CDK5 regulatory subunit associated protein 3) | protein interactions | 80279 | 164 | 80 | 19454 | 5460 |
TAB1,SEC63,ESR2,RPS3,TRIM44,SEC61B,CD226,LMNB1,MAPRE1,DNAJB6,CRMP1,NTRK3,RAB11A,TMED4,TMED5,CREBBP,HSCB,UFL1,MRPS7,STX7,PXMP2,MME,DERL1,RAB9A,RAB5A,HSPA8,SYVN1,FGFR1,SSR1,PIP4P2,ATG16L1,ST7,SEC62,OTULINL,PRNP,RPS10,DNAJC1,TMED9,TMPO,TSPYL4,MDM2,CD274,PTPN1,HSD17B11,GJA1,TUBG1,SMAD4,STYK1,HSPB1,RPL10A,TAX1BP3,PDIA3,DPP4,DDRGK1,PPM1D,SRPRB,KPNA2,RAB3B,HUWE1,UFM1,FKBP8,GLCE,ZNF787,TMED1,TMT1A,IGF1R,DISC1,SMNDC1,RAB4A,SIGLECL1,RPN1,STIM1,FURIN,CDK5R1,CCDC47,COMTD1,ESS2,MAP1LC3B,CARTPT,DNAJC25 |
| 1.367e-08 | -18.11 | TRIM21 (tripartite motif containing 21) | protein interactions | 6737 | 282 | 123 | 19454 | 5460 |
TRIM21,HSPD1,DCP2,G3BP1,ZBTB16,TRIM37,GABARAPL1,H1-3,ACTN4,B3GNT2,EZH2,IRF8,MAP1LC3A,RPRD1A,PHB1,HSP90AB1,IFI27,CCAR2,YWHAG,CTNNB1,DDRGK1,IFI16,DCAF4L2,TRIM8,CBL,RB1CC1,CD52,CDKN1B,UBE2D1,IKBKB,TRIM5,EP300,RAB5A,HTR1A,SKP1,UFL1,UBE2D3,EEF1G,CDKN1A,EHHADH,PRMT5,ZHX3,STAT1,TAX1BP1,ACTB,SAMHD1,MYC,CUL3,EXOC8,SETD7,LMNB1,FBXW11,YWHAZ,FAF1,MEPCE,MNAT1,TOLLIP,VRK1,RBCK1,MAP1LC3B,TBK1,FBP1,INSIG2,TP53,RNF8,DMAP1,UBE2N,UBE2G2,ACTA2,CDC5L,HDAC6,FCGR2A,GRAP,CALR,USP2,EMC4,XAF1,USP15,CRBN,SLC2A1,SMCHD1,BECN1,MTDH,MAVS,SQSTM1,BAP1,PML,TRIM3,IRF3,GABARAP,HSPA5,IRF7,NF2,PFKFB2,FBXW7,GABRA1,NEK2,GABARAPL2,CFTR,CDK7,SF3A1,HEXIM1,UBE2M,HAUS2,LMNA,TCP11L1,IDH2,TRIM27,UBE2I,OPTN,CREB1,EZH1,UBE2L3,NR1I2,NMI,VIRMA,DYRK1A,GMPS,IFI35,UBE2H,SPOP,NIF3L1,RC3H2 |
| 1.367e-08 | -18.11 | RPL36 (ribosomal protein L36) | protein interactions | 25873 | 471 | 188 | 19454 | 5460 |
UBL4A,KBTBD4,RPSA,H2AX,DDX42,TFCP2,DNAJC2,RBM34,SNIP1,RPL3,ABCE1,DHX9,IMP4,MEPCE,RPL17,ENY2,KARS1,API5,SNRNP70,RPL24,CDK12,RPS2,RPL10A,USP15,RPL32,RPS16,DNAJC1,CAND1,FZR1,DKC1,RBM42,SURF6,CFTR,RPA2,HEXIM1,TFB1M,ZNF770,RPL27,BAP1,RNF113A,RPS15,H2AC13,RPF2,RPL7A,ZSCAN25,MECP2,SPOP,RC3H2,UBE2H,PSPC1,RPS3,RPL10L,RSL24D1,TRMT1L,SOX2,RPS7,MSX2,GLE1,RND3,RPS23,RHOBTB1,RPL18,RPL31,PABPC1,SETD4,KRAS,VDAC1,RPS4X,RPL28,HNRNPDL,DDX50,RPL6,WWP2,RIOX2,DDRGK1,AGR2,DRG1,SRSF1,S100A8,RPS10,TRIR,RPL27A,PAFAH1B1,PIH1D1,RPS28,UFL1,STAU1,MYC,HNRNPC,BTF3,FTSJ3,H1-10,RPS26,ICAM1,NSA2,CMTR1,ZCCHC7,RPL10,ESR2,FBP1,AURKAIP1,TAF1D,RPL15,TOPORS,SRP72,RPL23A,PAK1IP1,VRK1,RPS13,RIGI,MOV10,GRSF1,SPATS2L,HDAC6,MPHOSPH10,RPL12,RCHY1,PWP2,RPL35A,AKAP17A,RPS14,ATG16L1,EEF1E1,UBA52,GRM2,METTL14,RPL26L1,RPLP0,RPA3,CCDC106,RPL4,FBXW7,HMGB1,NUCKS1,AATF,BRIX1,RPL26,USP14,PPP1CC,NONO,CCNF,METAP2,PRKRA,PTEN,RPS20,RPS12,RPL13A,RPL22,B3GNT2,OTUD6B,RPL29,ZNF397,EZH2,CHMP4C,RPS11,HNRNPA2B1,RPS24,TRIM37,MAP3K14,WDR12,RPL23,RPL8,RPL9,PHB1,MYEF2,RPLP1,HP1BP3,RPLP2,RPL7,DHX15,RND2,EMC9,NOP53,G3BP2,CUL3,CUL2,ZNF668,BRCA1,RPS5,RIT1,ZNF22,RPL37A,SEC61B,RPS9,RPF1,RPL35,RPL7L1,RPL19 |
| 1.399e-08 | -18.09 | miRNA-mediated gene silencing by mRNA destabilization | biological process | GO:0035279 | 101 | 57 | 18204 | 5365 |
MIR98,MIR130B,MIR211,MIR140,MIR23A,MIR26B,MIR190B,MIR340,MIR495,MOV10,MIR885,MIR1-1,MIR191,MIR145,AGO1,MIR9-1,MIR142,MIR135B,MIR223,MIR34B,MIR106B,MIR192,MIR24-1,MIR185,MIR130A,MIRLET7C,MIR212,MIRLET7B,MIR149,MIR519D,MIR146A,MIR96,MIR30B,MIR497,MIR100,MIR20A,MIR193A,MIR320A,MIR214,MIR625,MIR181D,MIR206,MIR342,MIR106A,MIR373,MIR16-1,MIR491,MIR195,MIR210,MIR424,MIR137,MIR200C,MIR708,MIR125A,MIR181C,MIR204,MIR423 |
| 1.402e-08 | -18.08 | SRSF6 (serine and arginine rich splicing factor 6) | protein interactions | 6431 | 492 | 195 | 19454 | 5460 |
RPF2,RPL7A,SUB1,RPS17,ZSCAN25,RC3H2,ELAVL2,UBE2H,RRP7A,RBM7,RPS3,CSNK2B,MACROH2A1,MRPS21,SRPK2,RSL24D1,HEXIM1,TFB1M,RBM23,TWNK,RNF113A,RPS15,RBM22,COPS5,SNRNP70,RPL24,NOL12,CDK12,RPS2,RPL10A,MRPS9,RPL32,RPS16,CAND1,FZR1,DKC1,TMPO,SURF6,CDC5L,IMP3,TP53,MRPL47,H2AX,RBM34,NUPR1,SNIP1,MRPL52,RPL3,DHX9,CDC40,MRPS33,IMP4,MEPCE,SRSF12,RPL17,MYC,BTF3,FTSJ3,PSMD14,NSA2,CMTR1,SF3B4,SNRNP40,ZC3H14,NCOA5,NGRN,SF3B1,EP300,SRSF2,TRA2B,STAU1,SAP18,MRPS7,IFI16,DDX50,WWP2,RIOX2,XPO1,NGDN,DDRGK1,MAGOH,CLK4,RBM5,SRSF1,EED,RPS10,HNRNPL,COMMD6,TRMT1L,AAMP,RPL18,RPL31,EWSR1,KRAS,H1-6,RPS4X,RPL26,PPP1CC,DNAJC8,CASC3,PPIG,CCNF,EIF4A3,PRKRA,NDN,RPL13A,VIRMA,RPS14,PIP5K1A,MRPS34,PICALM,ZCCHC17,METTL14,RPLP0,RPL26L1,ZNF574,CLK1,MTDH,DGCR8,HMGB1,RPL4,NHP2,UTP23,AATF,BRIX1,MOV10,APOBEC3F,MPHOSPH10,RPL12,KRR1,PRR3,AKAP17A,NCBP2,FBP1,CD2BP2,APOBEC3D,LLPH,TOPORS,NKRF,GLUL,ZC3H11A,HAPSTR1,PAK1IP1,HUWE1,VRK1,THRAP3,MRPS18C,RPS13,CUL3,NOP16,CUL2,ZNF668,FYTTD1,ZCRB1,LMNB1,RPS5,RIT1,ZNF22,RPL37A,RPS9,RBBP4,RPL35,RPL7L1,RPF1,RPL19,COMMD2,CCDC86,NOP53,MRPS35,HNRNPA1,TRA2A,DDX23,HNRNPD,RSBN1L,RPL8,FOLR1,PHB1,RPLP1,HP1BP3,RPLP2,RPL7,SRSF10,B3GNT2,E2F4,MAK16,RPL29,CHMP4C,HSPD1,SRSF8,SRSF7,DHX16,TNF,RPS27A,SRSF4,SSRP1 |
| 1.405e-08 | -18.08 | organic cyclic compound biosynthetic process | biological process | GO:1901362 | 1104 | 409 | 18204 | 5365 |
MED4,SUPT5H,NFYA,DCTD,ELOVL6,CDK9,SPHK2,GUCY1B1,NFE2L1,OGG1,FDFT1,RB1,ELOVL1,CITED1,TFB1M,CYP11B1,TYMS,PDHA1,MTHFS,CFTR,LDB1,CEBPG,GTF3C3,SDHB,ACOT8,HSD17B1,SHMT1,CYP17A1,CYP11B2,PPT1,DBH,MSX1,TEX12,PPP1R1B,PHB1,HMBS,SSU72,PIR,PLAC8,BCL6,PCLAF,S100A10,HINFP,MED11,ATP5MK,GTF2A2,GNPDA2,POLR2L,MNAT1,NR4A2,EGR1,CYP27B1,PYCR1,CYB5R1,GPHN,TCEA2,GTF2I,PRIM2,ATP5F1E,AK3,SDHC,TSPO,GNPDA1,FAXDC2,POLE4,MLF1,PPARG,LIPA,NSDHL,CYP7A1,GMPPB,SC5D,PAPSS2,CCNA2,TAF7,HSD17B11,TP53,ERCC3,IDO1,COX10,NDUFV2,VPS72,EPOP,DDX5,SLC25A39,NCBP2,HELT,NDUFAB1,ATXN1L,MTHFD2L,ACSS2,POLR1B,KLF4,UGDH,POLE3,POLR1H,ERG28,NHP2,SMAD1,MACROH2A1,DNPH1,SLC19A3,RGN,SUB1,ATP5PF,SART3,SOX9,TECR,MTF1,POLA2,TOPORS,MVD,CDK7,CYP1A1,NDUFA2,DPY30,POLB,SLC6A3,ATP5MG,GTF2H5,OSBP,GTF2B,TGFB2,PCNA,AANAT,SNAPC1,ATP5F1B,TWNK,RPRD1B,NUDT2,TCEANC2,LIAS,NFKBIB,CHRAC1,NDUFA1,QNG1,NPM3,DHX9,AMACR,UAP1,PDHB,ZNF345,ADRB2,PROX1,HAND2,PRDM4,ATP6V1A,MOXD1,GPBP1L1,AK2,NME4,CD28,CBFB,HSP90AB1,CDKN2D,POLR3H,PAAF1,IRF9,ZMPSTE24,THAP1,TAF5L,NDUFC2,GTF2H4,SMAD2,TAF2,POLR2I,FXN,APOBEC3F,ATP5PO,PLPP6,SLC19A2,DTYMK,DNAJC30,SPR,TPH2,WWP2,HACD2,MMUT,CREB1,RCHY1,MARS1,SLC25A1,ATP5F1A,NDUFS8,PMM2,POLR2D,OAT,DDT,HSP90AA1,NFIL3,MED21,NDUFB7,BARX2,USP15,GTF2F2,POLR3GL,NDUFA12,SLC11A2,FOS,DHRS11,TFCP2,NPPC,HINT2,WBP2,RPAP2,POLR2B,UCK1,GTF2E2,TERT,THTPA,NFKB1,ATP5F1D,NDUFB5,HSD17B3,SUPT3H,CCNH,NUDT12,APOBEC3A,MRPL12,NDP,G6PD,UMPS,ACAT1,CYP21A2,LHB,PCBD1,TCEA1,UCKL1,MED9,POLD2,TAF9,TRMT112,STAR,ELOC,MED23,PPAT,CH25H,MED30,MED10,MSMO1,HSD17B6,SGF29,PKNOX1,NDUFA5,EAF2,AKR1B1,NME2,POLDIP2,FOXA3,MED22,APOBEC3C,GFUS,NDUFB4,PTS,GTF2E1,SMARCB1,IVNS1ABP,BCL9,HACD1,RRM1,HMGCS1,DRAP1,CMPK1,GTF3C4,PIK3R1,GTF2IRD1,IRF1,NDUFS6,AK5,NIBAN2,SNAPC2,DEK,ELOVL4,SLC52A3,NDUFB8,PGRMC1,GPR37,DTL,ATP5PB,TAF10,NMRK1,ELOVL3,MED17,APEX1,ADK,NDUFS2,GMPS,MEF2A,SUPT4H1,ELOF1,CYP39A1,ADRM1,NME1,NDUFB10,GTF2H2,PTGES3,SMARCA5,WRAP53,SRC,SDR42E1,ATP5MC3,TCOF1,COX11,HSD17B8,SQSTM1,POLR2G,INSIG2,ATF4,POLR2F,TAF11,JAK2,PPP5C,MED31,NR1H2,ADCY2,KPNA6,ATP5MC1,AKR1A1,POLR1D,ACACA,RPRD1A,DCK,TERC,XBP1,PNPO,POLL,IL2,CYTL1,ATP5IF1,HIRA,CDK12,SNAPC5,RRN3,AR,TRIM24,RFC3,UQCC3,ENY2,EP300,DKC1,DR1,CYB5R3,KARS1,SIRT7,SKIC8,HSD17B10,NPC1L1,VDR,NPR2,CTNNB1,CYP2R1,ATP5PD,PRPS1,CEBPE,PYCR2,FUBP3,MTERF2,PRMT5,SMAD4,LBR,MED29,PAX6,ADCY3,ADSS2,MAD2L2,GFPT1,SNAPC3,GMDS,ELOVL7,WNT10B,DCAKD,POLR3F,NDUFS3,IREB2,GTF2A1,NCAPG2,LIG3,MED27,HDAC3,GUK1,CREBL2,MTAP,PRPSAP1,WDR82,SRD5A3,CDC73,STOML2,ACSL4,NKX3-2,ASMT,CYP27A1,DNTT,POLD4,POLR2C,POLR3B,GTF2F1,NDUFB6,PADI2,ACAA2,COPS2,PNP,ERRFI1,TRPC1,DLAT,FOXP3,GNPNAT1,SMN1,UCK2,UPRT |
| 1.438e-08 | -18.06 | PGAM1 (phosphoglycerate mutase 1) | protein interactions | 5223 | 151 | 75 | 19454 | 5460 |
ANP32A,RAB4A,CHMP4C,EZH2,TFCP2,SEC14L1,PCNA,TRIM37,BPGM,KRAS,ANP32B,SAR1B,RIGI,EMC4,IFI16,CALR,PDIA3,GLO1,GAPDH,TPM3,PPIB,HDAC6,AGR2,CD274,FABP5,ARL4D,AKR1B1,USP46,TES,TYMS,SUMO2,HYPK,MIF,ECHDC1,RAB11B,G6PD,MDM2,PGRMC1,CFTR,PRDX3,POLR1D,RPA2,LMNA,PPARG,UBE2M,SIRT7,DDX39B,RPA3,SOD1,BAP1,PEBP1,EP300,PSMA3,ATP5IF1,PGK1,STAU1,EMC1,PRCP,CUL3,RAB11A,PKP4,KDSR,BICD2,RIT1,DLST,ENO1,ENO2,TRIM24,UMPS,TENT5C,PRDX2,TAGLN2,KCTD9,TXN,VIRMA |
| 1.476e-08 | -18.03 | rRNA processing in the nucleus and cytosol | REACTOME pathways | R-HSA-8868773 | 191 | 97 | 10285 | 3229 |
TSR3,RPS9,MPHOSPH10,MPHOSPH6,RPS2,RPS11,RRP7A,RPS27L,RIOK2,EXOSC1,UTP6,RPS10,RPS15,RPL23,RPL26L1,RPL19,RPP14,RPL31,NOP58,PWP2,TRMT112,EXOSC4,RPL12,THUMPD1,RPL27A,RPS4X,RPLP0,EXOSC3,RPS26,RPS17,RPLP2,WDR12,UTP25,RPL8,RPL7A,RPS14,RPL24,RPL32,FAU,RPL3,RPSA,PNO1,RPL37A,UBA52,RPL7,FCF1,RPL4,RPL27,RPS12,RPS23,RPL26,RPP25,RPS7,RPL39,RPL10A,CSNK1E,RPL29,RPL10,RPL35,PELP1,RPL22,UTP15,NOB1,EXOSC8,RPS3,RPL17,RPL18,RPL9,WDR3,RPL10L,RPS13,RPS27A,EMG1,RPLP1,IMP4,ISG20L2,RPS29,RPL13A,RPL15,C1D,RPS28,DKC1,NOC4L,RPS5,KRR1,NHP2,RPL28,IMP3,RPL23A,RPL35A,RPS16,BUD23,RPS24,RPP21,RPL6,RPS20,RCL1 |
| 1.502e-08 | -18.01 | CPSF7 (cleavage and polyadenylation specific factor 7) | protein interactions | 79869 | 328 | 139 | 19454 | 5460 |
HSPA8,EP300,SNRPA,FXR2,B9D2,UFL1,NDUFS2,YTHDF1,STAU1,MFAP1,NUFIP2,MED23,CTBP1,FEM1A,MIRLET7B,SF3B4,TACO1,CPSF1,ESR2,SNRNP40,FBXO22,SNRPB,CCNQ,MYC,ARMC7,RCL1,GCC1,LMNB1,EWSR1,FAM76B,MIR9-2,HNRNPA2B1,SRSF4,G3BP1,DHX16,HNRNPF,MIR155,SPG21,B3GNT2,CSNK1E,RAF1,SUPT5H,RHOBTB1,SKA3,EZH2,PDHA1,CHMP4C,EED,TSG101,WDR82,MIR141,RPL9,FUBP3,FBXO32,SRSF1,WIF1,NUP35,SNX18,LYAR,SUMO2,LSM5,HNRNPA1,MIR29C,DDRGK1,CTNNB1,GAS8,WWP2,NDC80,MED4,MIR1-1,MAGOH,MIR10B,BAP1,DVL2,RPA3,SOD1,AATF,PFKFB2,PRMT2,MIR1-2,RBFOX2,TXNL4A,MIR34B,BRINP1,MREG,TFIP11,HEXIM1,MIR7-1,TOX4,RPA2,WWP1,MIR16-1,PSPC1,CCNF,CTTN,ENO1,PPP1R10,SRPK2,NDN,PPAT,NONO,AR,EXOSC1,SMAD2,RBM7,MECP2,TEX19,HAPSTR1,CPNE2,RPL23A,HINT1,EMC2,PQBP1,MEPCE,CD2BP2,ESS2,EXOSC8,RPSA,TAF2,MIR17,DDX42,GUCD1,DISC1,LDLR,MIR25,SMAD3,CDK9,CDC5L,FZR1,TOP1,CSNK2A1,PID1,TMA16,PPIL4,PCED1A,ERCC3,MOV10,CLP1,SNRNP70 |
| 1.507e-08 | -18.01 | DNMT1 (DNA methyltransferase 1) | protein interactions | 1786 | 221 | 101 | 19454 | 5460 |
CSGALNACT1,DNAJC19,UBE2H,MECP2,BRAP,H2BC9,RUNX1,CCNB1,SMARCA5,AKT1,VIRMA,UBB,TRIM27,CSNK2B,METAP2,ZNF330,CCNF,E2F6,RPA2,CCND1,ATG16L1,HSPA5,CXXC1,MBD3,HMGB1,FBXW7,KDM1A,HDAC3,SQSTM1,SIRT7,TRIM3,HELLS,RPA3,BRD3,SUV39H1,FZR1,RB1,SFRP1,CD274,DNAJC2,CBX3,DMAP1,EEF1A1,TP53,FBP1,SNRPG,DNAJC30,H3C1,RGS6,DNAJB6,RIT1,SETD7,SP1,YWHAZ,BRCA1,CUL3,MYC,APEX1,CBX5,DYNLL1,RBBP4,PRMT5,LMBR1L,PCLAF,DNAJC27,CTBP1,HSCB,B9D2,EP300,HSPA8,NGRN,PEBP1,SLU7,FKBP4,DCAF5,DDRGK1,CTNNB1,YWHAG,YWHAH,IFI16,SUMO2,COPS2,EED,TSG101,ARL11,MOB3C,CDK5R1,MTA2,EZH2,DNAJC25,ZNF263,RAF1,PAX6,KRAS,LASP1,RBBP7,UBE3A,CDK5,PCNA,PICK1,GADD45A |
| 1.519e-08 | -18.00 | GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1) | protein interactions | 2554 | 133 | 68 | 19454 | 5460 |
HSPA8,SYVN1,MTDH,SQSTM1,PHB2,SMC4,UNC45A,HSPA5,PSMC4,RPL27A,MYL12B,GABRA1,SSR1,HSP90B1,SLC25A3,TUBA1B,GANAB,PSMC5,TUBB,RPL35,YES1,SLC25A4,TECR,RPL19,SLC25A1,GABRG2,LDHB,CCT2,LMNB1,HSP90AA1,ATP1A1,SERPINH1,SLC25A10,HSPD1,SLC25A5,GABRB2,SLC39A7,TRIM21,HNRNPF,HUWE1,FARSA,CSE1L,RFC3,FLOT1,MSH6,TRMT1L,YTHDF2,CCT5,EEF1A1,TUBA1A,KIF2A,ERLIN2,RPN1,TUBB4B,HACD3,MAGED2,CAND1,ATXN10,HSP90AB1,OS9,CCT7,DDX50,XPO1,KLHL22,DDX23,ECD,HAX1,PPP3CA |
| 1.535e-08 | -17.99 | CHMP7 (charged multivesicular body protein 7) | protein interactions | 91782 | 81 | 47 | 19454 | 5460 |
SSR1,ST7,OTULINL,SEC62,USP8,PXMP2,EXD2,RPA3,RAB5A,AKAP1,RAB9A,DERL1,RIT1,FIS1,RAB11A,CREB3,TUFM,USP14,PAFAH1B3,SEC61B,RMDN3,RAB4A,STIM1,RPN1,MTCH2,DDX39A,DNAJC25,RAB3B,TRIM63,KRAS,FKBP8,TMT1A,HAPSTR1,ESYT1,WDR12,RAB5C,SLC25A46,LAMP2,MOV10,LAMP3,XPO1,DNAJC1,ARF6,CAV1,TMPO,PTPN1,HSD17B11 |
| 1.535e-08 | -17.99 | regulation of protein modification process | biological process | GO:0031399 | 1242 | 454 | 18204 | 5365 |
BRMS1,OSM,CUL3,BEX3,CCNB1,CAMK1,NBN,MIR218-1,NTRK3,TLR8,NTRK2,FGF23,IVNS1ABP,NSMCE3,MIR137,TICAM1,IL15,CEP85,NF2,UBASH3B,IL23A,SEMA7A,VEGFA,SRC,ANGPT1,RB1CC1,IL18,CSH1,TRIM21,THY1,PIK3CG,SQSTM1,LEP,HEXIM1,PHB2,TCIM,TAB2,IFNG,NTF4,PIK3CA,SPOPL,CAMP,MIR15A,CACUL1,ROCK1,PDCD4,RARRES2,G6PD,CCNF,CAMK2N2,TRAF6,GADD45A,FKTN,GSKIP,CCNH,TRIB1,TBK1,XRCC5,CCL19,DIRAS1,PIAS1,FAM161A,ARL2BP,PML,HINT2,MAP2K6,NHERF1,HCLS1,DUSP6,PHF23,CHI3L1,P3H1,DCUN1D3,TESK1,WBP1L,DRD1,PIH1D1,RALB,MINAR1,CD40,FGF16,SYK,STK11,STK38,CCAR2,NKX3-1,FBXW7,PRR5L,RPS7,SGF29,HDAC6,MIR24-1,MIR101-1,DUSP22,DCUN1D5,SERTAD1,YES1,TFRC,DUSP1,BIRC2,LACRT,UBE2L3,RAP1A,SMG8,PPP2R5A,RGCC,UBE2B,CREBL2,IFNK,TLR9,ATG7,MOB3C,NOS1AP,EMP2,HDAC3,DNAJB2,IFNA2,MIR21,MIR30B,UBE2S,TNIK,DNAJC3,RPS2,EHD4,CDKN3,LCP2,SFN,CLEC6A,NMI,SMYD3,MAD2L2,PAX6,ZNF592,PRKAG1,UCN,CD80,CD36,ROPN1B,ERRFI1,PPP1R12A,COPS2,PELI1,FLOT1,VEGFC,HAX1,SPRY1,PRNP,SNTA1,CLIP3,UBE2K,FGR,IL12B,UBE3A,MAGEC2,YWHAG,MMP9,CD86,IFNA10,GNAQ,CAMLG,UBB,ERP29,COPS7A,BAX,IL6,MOB3B,TOM1L1,FAS,KIT,PID1,ODAM,TOLLIP,UBE2N,SLC8A1,CARTPT,SOD1,DIRAS2,UBE2D1,CRKL,CTDSP1,CDK12,ARRDC3,CCND1,PAK2,MIR221,SKP1,PLAA,IL2,TGFBR2,FGF1,PKIB,NRP1,LRP6,JAK2,PTEN,TSG101,DEFB114,DERL1,CDK5RAP3,DVL2,PRKCE,CRY1,PPP1R8,GSK3A,AKT1,NOP53,TNFSF15,IL1B,SIAH2,UBE2V1,UBE2V2,FAM107A,TANK,GABARAP,SLCO3A1,IFNA13,TLR6,PIK3R3,SIRT7,IGF1,DR1,EP300,PDCD10,SPRED1,COPS7B,MT3,CCNI,CCND3,GH1,TNFAIP3,CTNNB1,CRTAP,SLC1A1,TXN,BAK1,HYAL2,GSTP1,GPNMB,MIR711,SESN2,FAXDC2,RAP2A,TSPO,CDKN1B,IMPACT,CCNA2,PAQR3,RPL23,UFL1,PPARG,MIR212,EGR1,RBCK1,IL34,IKBKB,CNOT7,TRIM44,LGALS3,EPO,IL7,CHRNA7,EZH2,IL3,PTPN1,FGF22,BAG2,ADORA1,GHR,RAP2C,PPIB,FGFR1,P2RY1,PTPRQ,MIR26B,TLR4,APLNR,TRIM27,DLG4,ZBED3,HUWE1,PTPN11,STK4,SVBP,TP53,SPPL3,FKBP8,CCNY,TAF7,DIPK2A,LEPR,MIR34A,IL13,ATG101,IL21,ACVR1,YWHAB,POMT2,CLDN3,F2,HSP90B1,NDN,CDKN1A,PSMD10,TNFRSF14,DCUN1D1,ADNP,RB1,STRADB,ILK,VPS28,HEXIM2,RGS2,CDK5,CORO1C,FGF7,DNAJC10,STUB1,HMG20A,PKIA,AGER,PYCARD,HRAS,DUSP10,BCCIP,TBC1D24,CAB39,CX3CL1,RAF1,MUL1,ROCK2,FGF3,MAP3K11,DDRGK1,ACTB,CAMK2N1,ADIPOQ,TNF,FGF17,PHB1,PPP1R1B,RPS3,TRIM6,CDKN2C,TRAF2,CX3CR1,IL4,NPTN,COPS4,PKIG,CNKSR3,SOCS5,HSPA5,CD4,HBEGF,ARPP19,PPP1R2,PSEN1,MIR146A,LILRB4,UBE2I,IGFBP3,MAVS,TAB1,SOCS3,CAV1,IFNB1,EFNA5,CAV3,SWAP70,CDKN2D,FKBP1B,HSP90AB1,AGAP2,BCL10,MIR132,HTR2A,INPP5K,IL12A,RWDD3,TPD52L1,MIF,PSRC1,CDK5R1,CTDSP2,PARD6A,SOCS4,CSF2,IL6ST,MAP3K12,HSP90AA1,EPHA4,TLR3,MIR106B,CCL5,PPIA,FZR1,CDC20,NUPR1,HSPB1,DUSP19,RCHY1,FERMT2,RTRAF,FLCN,SFRP1,STAT2,SOX9,CBL,NDFIP1,RGN,MIR20A,TADA3,DLG3,TOPORS,KDM1A,MACROH2A1,RIT2,ATP2B4,IL5,TLR7,FKBP1A,MMD,MAD2L1,COPS5,FCGR1A,DIRAS3,MAP2K1,HGS,DKK1,RABL3,DYRK1A,GCLC,RAP2B,PTPN22,ADTRP,PROX1,C9orf72,TNFSF18,GREM1,ADRB2,ISG15,TPPP,CCR7,TGFB2,CHP1,DUSP3,MAP2K3,OSBP,KRAS,SVIP,DBNDD1,SPRED2,NCK1,FGF10 |
| 1.539e-08 | -17.99 | CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) | protein interactions | 790 | 389 | 160 | 19454 | 5460 |
ACTR1A,EEF1A1,MAP2K3,TP53,NUPR1,PSMC3,PC,IGF1R,POC1B,MAP1B,PTGES3,FBXO25,MEPCE,VTA1,HDAC6,FGR,DNAJC7,PSMD7,SHC1,TUBG1,TES,COQ8A,CDK9,TMPO,MIF,FZR1,CFTR,GABRA1,CCND1,PSMC4,HEXIM1,UBE2M,GRM2,HSP90B1,RPA2,JUP,RNF113A,SQSTM1,DERL1,IDH3A,SIRT7,RPA3,BAP1,HSPA5,FBXW7,IRF7,FBXO7,CSK,UBE2H,SMAD2,ATP1A1,RC3H2,PTEN,PSMC5,OPTN,CCNF,RPS3,STUB1,UQCRC2,VIRMA,SRC,SH3BGRL,PRKCE,ADRM1,KCTD9,LGR4,TUBA1A,GFPT1,ISG15,PPP2R1A,TOP3B,RHOBTB1,MOB3C,POLR2C,HDAC11,CHMP4C,EZH2,TUBB4B,UBE3A,TESK2,RUVBL2,EWSR1,CCT8,TRIP4,FLOT1,PAK6,RAD21,PSMD12,RUVBL1,CDK20,KRAS,G3BP1,MAP3K14,CTNNB1,YWHAG,XPO1,ATG7,HNRNPA1,WWP2,PRPF19,PRKX,PSMD3,BCL2L1,POU5F1,CBL,HAX1,AGR2,KRT8,PHB1,MRTO4,ELK1,SRSF10,EGLN3,SUMO2,RHOH,EIF2S1,RPS10,PPP1CB,ACSS2,SLC25A3,PIH1D1,CSNK1A1,MAP2K1,PSMB7,RAB5A,HSPA8,HDAC5,DDX39B,BMPR1A,G3BP2,PSMC1,STAU1,UFL1,HSCB,CPSF2,BTF3,PSMD1,CUL3,GRB10,ACO2,MYC,RIT1,ILK,HTRA2,HSP90AA1,COP1,SP1,BRCA1,YWHAZ,SNRPD2,SMU1,BAD,MAD2L1,PPP5C,TUBB,TRIM29,PSMD6,ACTB,PSMD4,MATR3 |
| 1.694e-08 | -17.89 | MCU (mitochondrial calcium uniporter) | protein interactions | 90550 | 186 | 88 | 19454 | 5460 |
E2F4,ERLIN2,NDUFS6,ZNF526,CRELD1,NDUFA12,SYPL1,NDUFA4,HINT2,ETFA,KGD4,MRPS17,STOML2,MRPS35,NDUFV2,PDCD1,RHOG,MRPS26,PHB1,RHOH,NDUFS8,TOR1AIP2,NDUFAF3,MRPL12,RND2,SEC62,CCDC167,NDUFA5,SLC15A1,PHB2,HSCB,NDUFS2,MRPS7,PYCR1,MYC,HSD17B1,MRPS25,RHOB,DLST,TACO1,BAD,MAD2L2,NDUFAF4,APLNR,NDUFA2,ATP5PB,KBTBD4,MGARP,NDUFS3,MRPL49,MRPS18B,PDE12,RIGI,EDEM2,COX5A,SMDT1,COX4I1,MRPS9,SDHB,RAC2,EIF2B2,MRPL50,MRPL24,MRPS23,SLC38A2,CDC42,RPA2,MRPS34,TMEM263,RPA3,RHOU,SLC22A6,MRPL41,NME4,PYCR2,RALB,NDUFAF2,IGF2BP1,CCNF,IL2RA,PTPMT1,MRPS28,RPL13A,RHOJ,ARMC6,SLC25A4,GNAI2,UQCRQ |
| 1.698e-08 | -17.89 | PSMB8 (proteasome 20S subunit beta 8) | protein interactions | 5696 | 103 | 56 | 19454 | 5460 |
PSMD7,PSMD10,ELP6,PSMG2,PTDSS1,PFDN5,PSMD3,TCP1,NUP35,CCT7,PSMB5,PSMB4,MRPS9,PSME2,PSMB1,PSMC3,CCR1,POLR2G,DHX38,GNPNAT1,KIF2A,ACTN4,PSMB9,HADH,PSMA1,PSMA5,PSMA2,RIGI,PSMD12,PSMB10,PSME1,UBE3A,CLPB,PSMD14,POMP,CCT2,NLRP3,SNX5,PSMA4,PSMB2,PSMD1,PSMD6,ADRM1,PSMD4,PSMB6,PSMA6,PSMC5,STX17,ABCB1,PSMB7,PSMB3,PSMC4,CFTR,PAAF1,PSMC1,PSMA3 |
| 1.705e-08 | -17.89 | MID1 (midline 1) | protein interactions | 4281 | 118 | 62 | 19454 | 5460 |
KRAS,PSMA1,RASGRP3,PAX6,GSTT1,SAR1B,EIF1AD,IRF8,TUBB4B,PPP4C,STBD1,EEF1A1,PPP2R1A,MLLT6,UBE2V1,EPHB6,PTPN1,PSMB4,UBE2N,PPP2CB,PSMB5,TLDC2,IGBP1,PSMB1,UBE2D1,PSMD7,NQO1,PSMD3,UBE2E2,LRRC4,DDRGK1,UBE2K,UBE2D3,PSMC1,BAP1,IRF3,FAM50B,RPA2,FKBP1A,ZBTB42,UBE2W,EHHADH,GTF3C4,TUBB,PSMB6,UBE2L3,UBTD1,VIRMA,ESR2,RPS3,MID1IP1,TUBA1B,PSMA6,UBE2E3,PSMD14,HSP90AA1,CDKN2AIP,CUL3,PDE4B,ATG101,GMNN,AR |
| 1.707e-08 | -17.89 | ASXL3 (ASXL transcriptional regulator 3) | protein interactions | 80816 | 162 | 79 | 19454 | 5460 |
UBA52,MTX2,SF3A1,GSTM2,ISOC1,CDK1,NDUFA5,BAP1,H2BC12,HADHA,ARPC2,PRDX6,CLK1,PHB2,HSPA5,EIF4E,HSPA14,TUFM,ATP5F1A,YWHAZ,CCT2,PRSS1,PFDN2,HSP90AA1,RAN,TUBA1B,ENO1,RPS3,VDAC2,ALB,SNRPD1,SNRPD2,RTRAF,TUBB,RBBP4,BUB3,PRDX2,ATP5F1B,RPL22,RPS7,PPP2R1A,EEF1A1,CAPZA2,ARPC3,NME1,NDUFS3,GDI2,TUBB4B,ILF2,GLUL,CCT8,SLC25A5,HSPD1,HSD17B10,RTCB,HAPSTR1,RUVBL2,SEPTIN7,KPNA2,RUVBL1,CAPZA1,RIOX2,PRDX1,GAPDH,CSNK2A1,HNRNPA1,HBA1,SKIC8,NME2,DRG1,TSNAX,DDX1,SEC23A,MTAP,TOP1,RPS10,HSP90AB1,MBD5,CACYBP |
| 1.716e-08 | -17.88 | Metabolism of amino acids and derivatives | REACTOME pathways | R-HSA-71291 | 361 | 163 | 10285 | 3229 |
DIO3,CDO1,RPS26,SRM,PSMB9,RPS17,PSMD6,RPLP2,DIO1,DBH,RPL8,NDUFAB1,PSME2,ACAT1,RPL27A,IDO1,DIO2,SLC25A21,RPS4X,EEF1E1,CKB,RPLP0,PSMD12,ASPA,RPL3,TPH2,FAU,RPL32,PYCR2,INMT,RPSA,RPL7A,AANAT,ADO,MTAP,RPS14,SLC6A11,PYCR1,RPL24,PSMD7,RPS27L,NQO1,RPS10,SLC6A12,RPS15,RPL23,SLC6A7,PSME1,RARS1,TST,PHYKPL,KARS1,SLC6A8,ARG2,AZIN2,RPS9,RPS2,GAMT,PSMD14,RPS11,NMRAL1,SERINC1,RPL31,PSMC4,PSMB5,PSMA3,PSMB1,RPL12,PSMD3,PSMB7,RPL26L1,GCLC,PSMA2,PSMB6,RPL19,PSMB11,PSMC5,PSMB10,PSMA4,RPL15,DBT,RPS28,SEM1,MARS1,PSMB4,RPS5,PSMD4,RPS13,RPL10L,RPS27A,HSD17B10,OAZ1,RPLP1,GLUL,PSMA1,PSMC3,RPL13A,RPS29,DLST,SERINC3,RPS24,LIAS,PSMC1,RPS16,CRYM,GPT,ASMT,RPL6,ACADSB,RPS20,RPL23A,RPL28,PSMA6,PSMD1,PSMB2,PCBD1,AZIN1,RPL35A,CNDP2,ODC1,AUH,RPL26,RPS7,RPL39,PDHB,OAZ3,ASRGL1,RPL29,DLAT,BCKDK,RPL10A,PSMD10,PAOX,RPL37A,UBA52,RPL7,PAPSS2,RPS12,RPL27,RPL4,SLC25A10,RPS23,PPM1K,OAZ2,FAH,RPL9,RPL18,LIPT2,SHMT1,HNMT,GNMT,PSMB3,AMT,RPL35,RPL10,OAT,RPL22,PDHA1,PSMA5,SAT1,RPL17,TXNRD1,RPS3 |
| 1.763e-08 | -17.85 | ubiquitin ligase complex | cellular component | GO:0000151 | 313 | 137 | 19108 | 5553 |
RBCK1,FBXO42,ANAPC15,WWP1,FBXO3,ELOC,CDK8,MED21,KLHL7,SYVN1,ANKIB1,TRIM21,KLHL25,CRBN,KLHL15,DCAF5,TRAF2,MAVS,KLHL3,MED17,SPSB3,FBXO32,FBXL4,FAM8A1,CKS2,UBE2V1,FEM1A,PCGF3,RNF40,FBXO31,DCUN1D1,MED10,KLHL24,MED31,DCUN1D3,ARMC8,YPEL5,UBE2N,FBXO9,DCAF12L2,UBE2B,FBXO7,PCGF6,UBE2A,TRAF7,RNF20,BRAP,MED11,FZR1,UBE2D1,GPR37,BRCA1,ASB1,MAEA,RANBP10,DCUN1D5,DTL,OTULIN,SKP1,KLHL12,FEM1B,CDC26,GID8,KCTD10,KBTBD6,FBXL14,TMEM183A,RING1,TNFAIP1,FBXW11,FBXL7,ZER1,PCMTD1,WWP2,KLHL22,DCAF4,RNF14,CDC16,FBXL3,CDC20,RNF144B,CBX7,FBXO11,RNF7,ANAPC13,DCAF11,CBLL1,KCTD17,RMND5B,WDR77,DCAF8L2,ENC1,STUB1,UBE2D3,MKLN1,FBXO8,COP1,FBXL19,CDKN1B,FBXW7,CUL3,FBXW4,APPBP2,MED27,UBE2L3,CDC23,KLHL9,DCAF16,SPOPL,CACYBP,DET1,FBXO25,FBXO44,CUL2,MED30,GID4,ANAPC2,RNF11,CKS1B,UBE2S,DCAF4L2,CAND1,ANAPC4,RCHY1,ANAPC11,CCNF,TOPORS,OS9,SPSB1,DYRK2,PCGF2,SPOP,ANAPC16,PHC1,FEM1C,RNF8,MAD2L2 |
| 1.783e-08 | -17.84 | ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) | protein interactions | 488 | 323 | 137 | 19454 | 5460 |
ESR2,MAD2L2,SEC61B,CYB5R3,LMBR1L,ILK,RIT1,NSA2,VMP1,NTRK3,PLN,CUL3,GPR17,MYC,G3BP2,COIL,STAU1,SRI,ADRB2,EMC1,UFL1,NPTN,PMAIP1,HSPA8,HACD1,HDAC5,EXD2,BMPR1A,CSNK1A1,SIGMAR1,PPT1,VAPB,SEC62,NOTCH2,PGRMC1,FBXO42,BET1,NDUFS8,EGLN3,UQCRH,ATP6V1A,CORO1C,PHB1,HSPB1,ARMC8,RB1CC1,PEX3,AGR2,CTNNB1,DDRGK1,HSPB8,MARCHF5,ASB1,VDAC1,TRIM37,G3BP1,KRAS,EMC8,ZC3H7A,TMT1A,OTULIN,HGS,RNF126,PDHA1,EZH2,ERLIN2,LGR4,NCSTN,ISG15,RAF1,B3GNT2,VIRMA,SEC63,SH3BGRL,UQCRQ,PTPMT1,SEC61A1,ZNF330,CHRM5,CCNF,UQCRC2,UBE2H,ATP1A1,RIC3,HMOX2,SLC25A1,TNFAIP3,CCR4,FBXW7,PDHB,RNF113A,DERL1,SQSTM1,SIRT7,RPA3,BAP1,CYC1,GRM2,SSR1,CDK1,RPA2,CFTR,GABRA1,UQCRC1,KLF9,ZBTB2,LMAN1,MDM2,PTP4A3,TMPO,CDK9,HSD17B11,RCHY1,AIFM1,COQ8A,CD274,HACD3,ESYT1,SPP1,POR,ATP1B1,ADIPOR2,FAM20C,EMC4,DPP4,MDC1,FBXO25,PSEN1,EMC2,SLC16A1,NSDHL,MAP1B,NDUFS3,AURKAIP1,MTCH2,TP53,CCDC47 |
| 1.786e-08 | -17.84 | Mitotic G1-G1/S phases | REACTOME pathways | R-HSA-453279 | 143 | 77 | 10285 | 3229 |
MCM6,PSMA2,PSMB6,E2F4,PSMB3,RPA2,MCM4,PSMA4,PSMB10,CCNH,PSMA5,PSMC5,PSMB5,PSMA3,PSMC4,CDK4,ORC5,CDKN2D,CDKN1B,PSMB7,PSMD3,PSMB1,UBA52,PPP2R1A,UBB,POLE3,PSMD14,RB1,MNAT1,PSMD7,PSMD10,CCND1,PSME1,CDK1,SKP1,CDK7,RBBP4,PSMB2,PSMD1,AKT3,AKT1,PSMA6,CDK6,MYBL2,CDC7,PPP2CB,DYRK1A,AKT2,POLE4,MYC,PSMC1,POLA2,CCNB1,PSMD12,MCM8,CDKN1A,RPS27A,TYMS,CKS1B,CCNA2,PSMD4,PRIM2,TFDP2,MCM3,PCNA,PSMC3,PSMA1,CDKN2C,SEM1,PSMB9,CCND3,MAX,PSME2,RPA3,ORC6,PSMB4,PSMD6 |
| 1.836e-08 | -17.81 | TBK1 (TANK binding kinase 1) | protein interactions | 29110 | 384 | 158 | 19454 | 5460 |
TLR3,TNRC6C,PHF23,TBK1,EEF1A1,SOCS3,MAP1LC3B,AZI2,TF,CTNNBL1,RIGI,TICAM1,STX11,SIKE1,TCOF1,GARRE1,TLR4,KIAA1143,EXOC2,USP15,SSX2IP,USP2,EDEM1,ATP5MG,NFKB1,PPIL4,MIF,TOP1,NKAP,FZR1,MRPL24,ATP5PD,TOMM70,CDK9,EEF1AKMT3,ARL4D,RNF128,MANBAL,RPA2,LUC7L3,DYRK2,TFIP11,SCLT1,AKR7A2,ATG16L1,EDF1,FBXW7,NUCKS1,IRF7,KDM1A,IRF3,TMEM263,TRIM10,RPA3,MTDH,MAVS,SQSTM1,LGALS8,TLR9,BICD2,TRIM23,CA2,RALB,AKT1,TNFAIP3,DNAJC8,TRAF3IP2,DAPK3,TRAF1,SRC,SEC63,CDC20,CSTF3,SMURF1,CCNF,OPTN,TRIM27,VPS33A,CYB5B,POLR2C,STX12,MARCKSL1,RAF1,TRAF2,TRIM26,TNF,PELI1,TFG,IMMP2L,SRSF4,HSPD1,RUVBL2,PICK1,TRIM21,TRAF6,NCK1,PPM1B,HBA1,IKBKB,DDX23,MED4,RB1CC1,NDC80,PFDN5,PROS1,ICOS,HMGA1,ATG9A,PRPF19,YWHAH,XPO1,ATG7,HNRNPA1,SUMO2,LYRM2,RNF144B,HNRNPL,HSP90AB1,CHMP2A,CNTROB,EGLN3,TRAF3IP3,KRT8,NCOA5,EIF4B,IRF2BPL,MFAP1,BET1,TANK,SYK,MRPL12,BORCS6,STAU1,UFL1,FXR2,SKP1,RNF11,UPF3B,BMPR1A,EMG1,BIRC2,ATG3,HTRA2,HSP90AA1,COP1,FIS1,CUL3,CXCL1,TAX1BP1,TRIM46,LGALS3,ESR2,NFKBIA,UBE2S,S100A6,CRYBB3,LMBR1L,PHF21A |
| 1.837e-08 | -17.81 | FLNA (filamin A) | protein interactions | 2316 | 593 | 228 | 19454 | 5460 |
GRIK1,CAV2,PIH1D1,SYK,PAFAH1B1,SEC62,CD59,UFL1,TRA2B,STAU1,ADRB2,RNF41,HSPA8,HDAC5,EP300,FBXW11,PSMD14,ICAM1,COP1,PHOSPHO2,MYC,BTF3,SNRPB,PSMD6,SNRNP40,LMBR1L,TRIM44,SMU1,MCPH1,PHF21A,RPS23,KLHL12,TOP3B,SOX2,TRAF2,ISG15,EEF2,RAB8B,PABPC1,CCT8,MYO1B,AGR2,CBL,IFI16,PFDN5,WWP2,YWHAG,SUMO2,HSP90AB1,KCND2,WDR82,CORO1C,EED,RPA2,DRD3,HEXIM1,UBE2M,PRKCA,DDIT4L,SPTBN1,CDC42,CFTR,WSB1,KDM1A,MARS1,HSPA5,BAP1,NLE1,PSEN2,PML,BANF1,RNF113A,RC3H2,DTL,ATP1A1,UBE2H,KCNJ2,AKT3,CCNB1,ARHGAP21,CFL2,CFL1,KCTD9,RALA,DAPK3,MAP3K3,SMURF1,SRC,DISC1,CAPZA2,ARPC3,NUPR1,FURIN,RRM1,KBTBD4,MTCH2,TP53,INSIG2,AKAP12,MEPCE,CAPZA1,PALM2AKAP2,MAP1B,POC1B,ABCE1,CYBRD1,RFLNA,USP15,MAP4,KARS1,CD81,FZR1,SPPL3,PREP,ALKBH3,TOR1AIP2,PPP1CB,DET1,GPC1,FBXL4,CRY1,DCAF4,BRCA1,MYO6,HSP90AA1,PFDN2,PFDN4,VMP1,CUL3,OPRM1,CUL2,PDE4B,RBBP4,ACTB,GRM8,GNG12,PELO,AP2M1,SNRPD2,EZH2,CHMP4C,ITGB5,RAF1,ACTN4,RBBP7,G3BP1,S100A10,FLOT1,SAR1B,CPLX1,NUDT5,SKIC8,WDR12,TLR10,PSMD10,HNRNPD,DCAF11,PDIA3,PSMD3,PRPF19,HNRNPA1,SPTAN1,KCTD10,FOLR1,PHB1,GJA1,CDK1,LMNA,JUP,METTL14,TMOD1,WTAP,WDR5B,ATG16L1,FBXW7,PIAS1,RPA3,SIRT7,MTDH,SQSTM1,DCAF16,TXNIP,AP2A1,NAPA,CDC73,MAPRE1,CTSD,CIAO1,SEC13,USP14,PPP1CC,AR,TMOD3,NDN,NREP,VIRMA,SMAD5,CCNF,CTTN,ZBTB18,PTEN,UAP1,ACTR2,PPME1,ILF2,FBP1,TRIM6,MAMDC2,EEF1A1,DRD1,CAMK2G,PSEN1,MDC1,RIGI,RAB1A,PPP1R12A,SEPTIN7,HDAC6,PPP1R18,PLEKHF2,PRNP,CDK9,CAV1,SMAD3,AIFM1,PTPN1,MYBL2,TES |
| 1.842e-08 | -17.81 | RSL1D1 (ribosomal L1 domain containing 1) | protein interactions | 26156 | 434 | 175 | 19454 | 5460 |
STIM1,CHMP4C,RPS11,RPL18,RAF1,ISG15,NCSTN,H1-3,MAK16,SOX2,RPS7,H1-6,G3BP1,KRAS,VDAC1,SRSF4,RPL28,RPS27A,LECT2,SSRP1,RPL31,PPAN,ARGLU1,TRIM11,RPS24,DDX23,MED4,POU5F1,IFI16,RPL6,CREBL2,DDRGK1,RPS10,NOP58,POLR3F,LYAR,RPL8,FBXO32,EED,HP1BP3,PPARG,MTF1,H1-5,FXR2,UFL1,EMC1,NOP53,STAU1,COIL,G3BP2,NGRN,FOS,SF3B1,HSPA8,CCDC86,H1-10,FTSJ3,LMNB1,DCAF4,BRCA1,ZCRB1,RHOB,RPS5,H1-1,NSA2,RIT1,MYC,NOP16,CUL3,ZNF668,BTF3,MATR3,SNRNP40,FBXO22,RPL35,RPF1,RPL7L1,APEX1,RPL19,RSRC1,RPS9,LLPH,DNAJC2,RBM34,HBP1,NUPR1,TP53,RPSA,H3C1,NOC4L,IMP4,TGFBR2,RPS13,SRSF12,MEPCE,RPL17,SNIP1,RPL3,EMC2,CHCHD1,SNRNP70,MPHOSPH10,RPS2,NOL12,CMSS1,DPP4,MOV10,GRSF1,RBM17,COPS5,CSNK2A1,HDAC6,FZR1,RPS16,CAND1,MDM2,DKC1,SURF6,ZBTB2,NOP9,METAP1,KRR1,CDR2L,RPL32,PRR3,ARL4D,LMNA,RPA2,METTL14,ZNF574,RPL26L1,RPLP0,KLF4,RPS14,CDC42,KLF12,NPM3,RPS15,RPL4,HMGB1,FBXW7,BRIX1,UTP23,AATF,BAP1,RPA3,PML,NLE1,SIRT7,MTDH,RNF113A,TRIM23,RC3H2,ELAVL2,ATP1A1,UBE2H,RPF2,AKT1,SUB1,RPL7A,RPL26,H2BC9,ZSCAN25,PPP1CC,RHOJ,RPL13A,SRPK2,PSPC1,RPS3,OPTN,CCNF,ZNF330,CAB39,PRKRA,PTEN |
| 1.854e-08 | -17.80 | MRPL15 (mitochondrial ribosomal protein L15) | protein interactions | 29088 | 208 | 96 | 19454 | 5460 |
NUP42,KRAS,IMMP2L,SRSF4,MRPS17,SRSF7,HINT2,NDUFA12,SOX2,PPP2R1A,SRSF10,GATD3,FAHD1,MRPL18,RHOG,MRPS26,RPL6,MTRF1,TRA2A,MRPL9,HNRNPA1,MRPL57,HSCB,TMEM177,EXD2,SNRPA,NGRN,MED23,MRPS18A,MRPL12,RPL35,PSMD4,MRPL23,RPL19,PRRC2A,ESR2,RPL10,MTG1,DLST,TACO1,MRPL13,RIT1,SCFD1,PMPCA,MTG2,AUH,MYC,MRPL16,RPL17,FKBP8,MEPCE,FASTKD5,SNIP1,MRPL52,RPL23A,MRPL49,MRPL51,GFM2,MRPL47,MRPL11,METTL15,AURKAIP1,APOBEC3D,MRPL50,CAND1,NOP9,MALSU1,ALYREF,SSBP1,PRR3,TMEM70,CHCHD1,SNRNP70,RPS2,GRSF1,MOV10,COPS5,MRPL41,MRPL40,MRPL17,MRPL20,RHOU,GFM1,GRM2,CYC1,MTRES1,KLF4,RPS14,RBMS2,CDK7,MRPL10,RPL13A,MRPL53,UBE2H,TUFM,RPL26 |
| 1.863e-08 | -17.80 | HDGF (heparin binding growth factor) | protein interactions | 3068 | 306 | 131 | 19454 | 5460 |
NMI,DEK,RPL22,TXN,BUB3,EIF2S2,MSN,TRIM24,MACROH2A1,OPTN,CCNF,EIF2AK2,ENO1,PDCD4,UBE2H,AKT3,SMARCA5,SUB1,PTPN11,BRIX1,EIF5B,H2BC12,BAP1,UBE2M,MACROH2A2,CDK1,LMNA,SSR1,XBP1,CCND1,UBA52,TPT1,TMPO,CDC5L,RPL35A,TOP1,PRNP,PWP2,AIFM1,RPL32,ALYREF,MAP4,SMAD4,CSNK2A1,API5,MPG,MOV10,OLA1,RPL17,RIGI,MSH6,H3C1,KPNA2,HNRNPK,CPNE2,DHX9,HSD17B10,PSME1,SRP72,CDK8,CBX3,DDX39A,UBR7,GPR37,RPL10,RPL19,APEX1,RPL35,RBBP4,ACTB,INTS10,PRMT5,SNRPD1,RAN,SP1,RCL1,H1-1,CKB,LMNB1,H1-10,RFC5,MYC,EMC1,SRSF2,STAU1,HSPA8,EP300,YAF2,DDX5,THOC3,RFC4,XRCC5,SLC25A3,CNDP2,PIH1D1,CTBP1,ACTL6A,DHX15,EIF2S1,HNRNPL,LYAR,HP1BP3,MRTO4,SRSF1,DDX1,DRG1,AGR2,CTNNB1,BAZ1B,DDX50,POLDIP3,RFC3,SSRP1,RUVBL1,EWSR1,SRSF7,SLC25A5,HNRNPA2B1,ABCF1,ZRANB2,RBPJ,RPS11,GTPBP1,RPS23,EZH2,PLS3,EXOSC3,JUN,H1-3,KIF2A,EEF2 |
| 1.871e-08 | -17.79 | regulation of cellular component organization | biological process | GO:0051128 | 2455 | 841 | 18204 | 5365 |
ARF1,LCMT1,CLIC4,FKBP8,TMEM30A,PFDN1,MIR133B,SKA2,LPAR1,ITGA6,SCN1B,CLEC7A,SGIP1,CHMP1B,SCAMP5,FGFR1,RAC2,GHITM,TFPT,TRIM27,CEP97,CCL11,C1QL1,TOMM70,ENC1,PTPN11,HUWE1,IKBKB,MKKS,RAD21,AP1AR,EPO,TPBG,EZH2,CHRNB2,CHRNA7,ADCK1,ESR2,CAPG,SESN2,PRKCQ,TSPO,RAP2A,TMOD1,DCP2,STK24,F11R,PTGER4,CSNK1A1,PAQR3,SFRP4,CLSTN3,PPARG,RAF1,STN1,IL10,ROCK2,RBBP7,TBC1D1,ADIPOQ,CRLF3,H1-1,ETF1,CNTNAP1,RPS3,TMEM106B,RAB11A,CDKN2C,TRAF2,MIR145,MSX1,EPHA2,VPS28,KLK6,INO80C,NTNG2,RGS2,STX1A,PTK7,MAPRE2,BCL7B,HMGB1,YTHDF1,CORO1C,ABHD17A,MBL2,ZNF304,PYCARD,HRAS,STXBP6,LRRC24,TAPT1,RHOB,TRIM46,PREB,S100A10,CXCR4,TBC1D19,SPHK2,SH3GLB1,ATG3,CXCL10,PSMD10,TBC1D13,ATAD1,LGI1,ADNP,CTTN,ASIC2,STK38L,TBC1D5,LDB1,LMAN1,NEFL,DDR1,TBC1D17,BCL7C,PLSCR1,PIP4K2C,F2,THOC2,HNRNPA1,ZNF207,G3BP1,CDC20,MIR142,MYC,IER3,TMSB10,ANAPC4,INPP5K,MARCHF5,SSBP1,APLN,CDK1,MOV10,PDCD5,PSRC1,TRIM36,WDR45,MTCH2,CDK5R1,GDI2,SNAP25,HSP90AA1,SYNDIG1,ARPC2,TNKS,GPBAR1,SMG5,MEAF6,USP8,CAV1,IFNB1,PFDN6,TRIM11,MCOLN1,KCTD17,MEF2C,CNTROB,CAV3,MSTN,FKBP1B,VGLL4,CDKN2D,CD28,SNX3,MIR31,BRCA1,MIR208A,GFI1,CRB3,RUNX1,ZMPSTE24,HBEGF,PTN,AP2A1,MTM1,PSEN1,TNKS2,CLDN1,FCN2,TGFB2,IL1A,MIR144,PLSCR3,SVIP,SMC4,TF,NCK1,IL2RG,SEC22B,SPC24,DYRK1A,TRIM37,GCLC,WASL,PTPN22,PROX1,TOM1L2,ADTRP,WASF3,GREM1,VPS4B,CDH13,PIWIL2,SNX33,TPPP,RETREG3,RIT2,TMOD2,MACROH2A1,CAV2,TTC8,NCKAP1,PFDN2,MIR200C,CCT2,MAD2L1,CD151,CLRN1,SUMO1,RAP1B,HNRNPC,FEN1,TNR,BAZ1B,CTNNA2,CCL21,MIR20A,PICALM,SLC35F6,IFNG,CAMSAP2,BIRC5,STX5,TOM1,USP30,RAB8B,SRC,SH3BP4,CALY,DAG1,C1QL3,ANGPT1,SMARCA5,MGARP,MTMR2,FAM162A,EPS8,SQSTM1,HNRNPK,COTL1,CBLL1,NDC80,SMARCB1,MECP2,SLITRK1,PRMT6,SNX17,FBXO7,TICAM1,NFE2L2,BNIP3L,BMPR2,SEMA7A,EI24,PQBP1,MKLN1,RND3,SHOC2,CGRRF1,CTNNBIP1,ACTR2,NBN,FLRT2,NTRK3,CCT5,TFIP11,NTRK2,SMAD3,CD63,DUSP22,ALKAL1,CDH8,SARM1,SLC7A11,TFRC,ESAM,HNRNPD,CCN3,SLITRK2,RAP1A,RALB,CISH,MINAR1,MIR205,CLU,SETD5,ADIPOR1,CCDC32,STAP1,FCGR2B,PML,DISC1,HCLS1,P3H1,FGF13,TESK1,FUT9,IL15RA,VPS16,UBLCP1,NLGN2,CCNF,MIR222,NEK2,LAMTOR1,CD38,CD2AP,LRTM2,LRRN1,SFTPD,CCL19,FGR,MIR185,UBE3A,CXCL9,FOXP1,CFL2,BTG1,CRMP1,CSK,SLITRK5,AURKAIP1,LDLR,ENO1,CPLX3,USP6NL,VDAC1,MORC2,NCKIPSD,HAS3,VPS33A,FLOT1,SNAP91,PPARA,PAK5,GPC4,MAP4,TMEM196,NEUROD2,CHMP2A,LYAR,SIN3A,RERG,NDUFS3,ARPC3,RMI2,PMAIP1,SNAPIN,MIR210,BAP1,CD36,GPRASP3,RGCC,UBE2B,DNM2,SMURF1,RTN4,MIR30B,MIR21,ANAPC2,MSX2,PACSIN3,CAMK2G,BOK,EP300,TTL,PDCD10,VDAC2,CCL24,RALA,GPX1,CYFIP2,CTNNB1,HYAL2,NPR2,NOP53,TBC1D4,NDNF,LMNA,SMAD4,INO80E,DRD3,PRMT5,MIR92B,VLDLR,PKIB,BST2,CAND1,TIRAP,ATP8A1,BCL2L1,STXBP1,MCPH1,PTEN,GRID1,BAD,RAB27A,TUBA1A,L1CAM,DVL2,GSK3A,MLLT11,CD14,EIF2AK2,RIOK2,CDC42EP2,LMO4,SNX12,ODAM,CRKL,MSN,PLAA,MIR221,ATP5IF1,MAP1S,CDK2AP2,TP53,ACTL6B,SDCBP,MDM2,SDC4,TNFSF10,NEK7,EHD1,HPCA,SKA1,MIR1-1,SOST,SYNJ2BP,PTPN1,LAMB2,CYRIA,HSPA8,TMEM33,CHORDC1,ITGAV,RAD1,CRABP2,JADE1,ARF4,DLG4,TLR4,APLNR,TMEM14A,HOMER1,KLF4,CRBN,CYP27B1,GPM6A,CEP70,APOC2,MIR335,LGALS3,ATAT1,LRFN3,FAF1,MIR195,B2M,CCSAP,MAPRE1,CHMP5,RHOG,CAMKV,PI16,KLHL22,CDKN1B,TP53TG5,CXCL13,DSTN,CHMP4C,SCFD1,ANKRA2,CAPZA1,CX3CL1,MUL1,PPT1,ACTB,SPATA4,HAUS2,TNF,MID1IP1,LRRTM2,RUVBL1,ING1,PHB1,SLAIN2,FCGR2A,SLC25A4,HFE,PFDN5,CXCL12,BCL6,CDK5,STUB1,CCT8,IL1RAP,EMILIN1,MIR98,TBC1D24,FBP1,HECW1,RNF5,MIR105-1,TMSB4X,TMEM39A,CDKN1A,TBC1D10C,ZNF365,LRRC4B,WDR44,SLC25A5,IK,RB1,RAB31,TPPP3,CNTN1,GJA1,MIR214,MIR17,MIEN1,TBC1D16,TENM3,ARF6,CLDN3,CDC16,IL2RB,RAB4A,EPHA4,ADD2,ZDHHC15,SPEF1,CST3,FCHSD2,FZR1,CDC42,SOCS2,LRRTM3,NUPR1,CRYAB,FERMT2,IGF1R,FLCN,SFRP1,ARFIP1,LILRB1,EIF5A2,YWHAH,FRZB,C1QL2,CFL1,CSF2,UST,SSH3,MAVS,CPTP,TYROBP,ANAPC15,SEPTIN7,CDKN2AIP,RUVBL2,AP2M1,EFNA5,SWAP70,MAD2L1BP,MYD88,TACR1,IL4,TRIM54,NPTN,OPHN1,HTRA2,HSPA5,FXN,CBLN2,MIR149,FAM98A,IGFBP3,DUSP3,OSBP,PPFIA2,MIR9-1,ADD1,RAB29,DKK1,SPOCK1,RAB1B,TMEM182,SPP1,C9orf72,ADRB2,SEMA5A,CCR7,ISG15,DNPH1,ING5,KDM1A,ANAPC11,RASGRP2,IL5,FCGR1A,SKA3,IGFBP4,DRG1,MAP2K1,CBL,ABITRAM,STAT2,SOX9,CSNK2A1,EXOSC4,SUB1,GHRL,IFRD1,RAB3A,DLG1,CNOT6,SNAI2,BECN1,CBLN1,NAPA,FIS1,EFNB1,ICAM1,CDC23,SPTAN1,BMERB1,NLGN1,PAFAH1B1,CD47,TIAM1,PIK3CA,CTTNBP2,SYT2,P2RY12,ROCK1,NEO1,SURF4,SERPINI1,NEGR1,CCDC85B,THY1,STX18,VAC14,HNRNPA2B1,PMP22,FASLG,RNF41,AP2S1,MTPN,PRELID1,NSMCE3,IL15,LAMTOR2,NF2,CAPZA2,VEGFA,CPLX1,YWHAZ,AMIGO1,NR2E1,PIK3R1,PIK3R2,SSRP1,CUL3,CCNB1,OSGIN2,CAMK1,BICD2,STMN2,TCP1,FZD4,CAPN2,CERS2,XPO1,PARP2,WEE2,DCUN1D5,SPTBN1,NAIF1,CNOT6L,RAB33B,DUSP1,SLC23A2,BIRC2,TRIM32,TMOD3,ACVR1B,DERL2,NUF2,ARFGEF1,CH25H,SYK,TMED9,STK11,CCAR2,POLDIP2,FBXW7,HDAC6,EAF2,S100A8,NUP62,EHD3,MAPKAPK5,TUBB,PDE2A,PHF23,CCL2,DCUN1D3,SERTAD3,RAB5A,TLR2,G6PD,MIR183,MYLIP,FKBP4,DMPK,XRCC5,CYRIB,PPIF,CDC42EP3,FEZ1,DPP4,TMEM97,PICK1,FCER1G,TBC1D25,MMP14,G3BP2,LRRTM1,GPM6B,MMP9,PYDC2,ACAA2,CHMP1A,MIEF1,BAX,SDC2,TOM1L1,IL6,ACTL6A,PLXNC1,SLX1A,SMARCE1,DAPK3,PRNP,HAX1,IQSEC1,CLIP3,PLEKHO1,SAR1B,SIPA1L1,WNT10B,TPPP2,GPR65,MAD2L2,PAX6,MNS1,NCAPG2,VPS18,UCN,CDC42EP4,CHMP2B,SMARCD3,TNFRSF1B,PLCB1,TNIK,CDC73,DNAJB2,PPP1R10,SYT4,DNAJB6,SFN,EHD4,SNX18,SIRT7,PIP4P2,CALR,DKC1,IGF1,CNOT2,MT3,TOX,OXTR,GH1,BAK1,MAP1B,AKT1,IL1B,TGFB3,ELAVL4,PPP3CA,WNT7A,FAM107A,ARFGAP1,VPS39,CCT7,SLC25A31,SERTAD2,ITGA2,TLR6,NR1H2,PLA2G5,PCSK9,NRP1,TSG101,RGMA,PARL,LCP1,ATF1,GLCE,PRKCE,EGLN2,CPLX2,PID1,FLRT3,KIT,RPL13A,PFDN4,MET,BUB3,RND2,AR,LHFPL4,SOD1,CNR1,PSMG2,IL2,PAK2 |
| 1.896e-08 | -17.78 | transport | biological process | GO:0006810 | 3615 | 1202 | 18204 | 5365 |
AZGP1,GHITM,DDIT3,LRRC8A,TRIM27,SLC4A10,TOMM70,NETO1,CCL8,ADORA1,CHMP1B,SGIP1,SCAMP5,ICA1,PLPP4,P2RY1,SRSF1,TMEM87A,COMT,ARHGAP21,SLC39A7,VPS4A,SCN1B,CYGB,CLEC7A,ARF1,SLC39A13,CLIC4,SVBP,TMEM30A,NOP9,GNPTG,BLOC1S2,ABCC5,TAF7,CXCL8,CCDC22,OSTM1,YIPF4,YIF1A,RPL23,RAB39B,RACGAP1,LIN7C,LIPA,DESI1,ANKRD50,CYP7A1,ARCN1,KCNK10,PPARG,STX12,SESN2,CALHM3,CETN3,SLC35E3,RHOJ,UFD1,TSPO,GABARAPL2,TMED5,GLE1,RABIF,ATP5F1E,RAB32,CHRNB2,UPF3B,OSBPL8,CHRNA7,FBXO22,SLC25A11,CEP41,MREG,CHCHD4,SLC17A5,COX5A,MKKS,AGAP1,CLN8,TRAK2,AP1AR,SRP54,SLC6A4,PTGDS,HRAS,PYCARD,AGER,STXBP6,MFSD3,PLEKHF1,RHOB,TRIM46,S100A10,PREB,VPS28,TMEM184C,RAB6A,CDC42SE2,STX1A,CXCR1,GABRB3,HMGB1,CORO1C,PITPNB,RAB6B,VAMP7,SNX14,TMEM106B,RAB11A,RBP5,TMEM144,HRH3,RAB2A,MRGPRX2,RAF1,SLC39A10,ARMCX3,CACNB3,TMEM50A,COMMD3,POLDIP3,APPBP2,ORAI2,PLSCR1,SLC35B4,EXOC5,SLC29A1,CCR2,EXOC8,TRAPPC10,TBC1D5,TMEM184B,LMAN1,CFTR,NEFL,SLC22A8,TBC1D17,DDR1,SCN2B,KCNQ5,RAB9B,ANKH,STRADB,CTTN,TRIM23,ASIC2,FBXW11,SLC35E4,PLEKHJ1,GLRA2,HSP90B1,CYC1,JPH4,CIDEB,BORCS8,ATG3,KCNA3,VAMP2,TIMM23,PLEKHA8,INPPL1,SPRN,PEX3,TBC1D13,MTCH2,CNIH4,GDI2,MAGED2,SNAP25,NDUFA12,CHRM5,BTF3,HSP90AA1,SYNDIG1,SFXN2,HTR2A,ATP6AP2,APLN,KCNJ2,TRAPPC13,REP15,SLC20A2,SLU7,FAF2,GOSR1,ZFAND6,SLC25A1,HSPB1,G6PC3,SLC35A1,SNCB,TOMM40,ATP1B3,TUBA1B,CREB1,IER3,CLBA1,RIMS3,THOC2,SEC61G,GLRA1,TMEM50B,HNRNPA1,PREPL,WWP2,CASK,DNAJC19,COX7B,SLC43A2,PEG10,SLC25A28,ATP6V0B,AP2A1,SLC19A2,LILRB4,GJC1,ATG9A,PSEN1,EGR2,MTM1,ARL6IP5,UBE2I,ATP1A3,CLDN1,VAMP5,IFT57,SMAD2,WWP1,SNX3,TRAM2,SLC38A3,ALKBH5,GABRB2,TNPO3,ZMPSTE24,LCA5L,CAV3,PLEKHF2,BLOC1S3,FKBP1B,NME4,RAB1A,SLC25A45,NDUFA4,AGAP2,NECAP2,TNKS,SMG5,MPC1,SLC20A1,ACHE,CDR2L,STARD3NL,CAV1,FTL,ATP6V1A,MCOLN1,TOM1L2,VPS4B,AP5S1,RBP2,FOLR2,TIMM10,MARCHF3,SNX33,EIF2D,FABP7,ATP6V1G1,HSBP1,PEX13,SLC5A6,GCLC,TRIM37,SELENOM,NDUFA1,WASL,TMEM115,CPT2,TF,CPT1B,FGF10,SEC22B,ATP5F1B,FCN2,CRYBA1,CHP1,PLSCR3,SLC7A14,KLHL12,STBD1,DPY30,SLC6A3,RIMS4,PICALM,ATP1A2,NDUFA2,SLC35F6,ATP1B1,TST,AP5M1,ARL5B,PLA2G12A,ATP5PF,ARHGAP25,SLC30A7,CCL21,COPS5,MFSD14B,CRHR1,FABP12,RAP1B,RNF126,SLC25A24,FOSL2,CHGA,LRP12,PRKCB,COX8A,AFTPH,CTBP1,ACTN4,SVOP,SLC35A5,CAV2,XPO5,CHRM1,TTC8,HPS6,ATP2B4,RER1,TM9SF4,RAB40AL,LEP,SQSTM1,PHB2,PLCB2,SLC25A23,ATP5MC3,ZMAT3,CALY,SRC,ADRA1A,SH3BP4,SLC25A46,DAG1,PPID,KCNJ11,MGARP,EXT1,NME1,SLC25A21,GOLGA5,TOM1,SFTPA1,HBA1,RAB8B,TMCC1,ARL4A,SERINC3,SNX10,SLC39A3,SEC23A,DYNLL1,STX5,BLOC1S5,SHOC2,SNX11,RGP1,ACTR2,TMED3,TOMM7,NTRK2,BORCS5,STARD4,AP3S2,SLC30A5,SLC25A32,TRIM3,NIPA2,DNAJC5,LYSET,EHBP1,ALYREF,SNCG,SNX1,BNIP3L,MIR29A,SYS1,LYPLA1,SLC41A1,SLC38A1,SEC61A2,KDELR1,TRAPPC4,TOMM6,SFXN1,GOLGA7,MECP2,MAIP1,SIGMAR1,COX17,SNX17,AKR1C1,GRPEL1,TMEM167B,FCHO2,FCGR2B,ACTR1A,NDUFA5,RALB,CLU,KCNG3,RINT1,SLC25A3,CLTRN,SEC63,GIT2,SELENOK,NXT2,TFRC,CRHBP,TUSC2,CYBRD1,EIF4A3,RAP1A,PLSCR4,RILPL2,TMEM108,KCNJ10,CD63,ATG4A,PLP2,ATG16L1,SLC7A11,LMBR1L,RAB19,UMPS,JPT2,ESYT1,GRM2,RAB35,C2CD2L,CCL19,SFTPD,NLGN2,VPS16,FXR2,TSPO2,KCNJ3,DNLZ,NDP,TICAM2,LAMTOR1,CD2AP,SLC25A20,SRI,FGF13,NDUFB5,KCNJ8,SSNA1,PML,SLC25A44,SYBU,NECAP1,MRPL18,SRPRA,PRSS12,SLC11A2,HCLS1,UPRT,FLOT1,SNAP91,SLC1A3,SERPINA5,GRM1,LRRC8B,AP1S2,CNNM4,CPLX3,HSPD1,LDLR,USP6NL,GRIK1,AP1G2,TRPC1,VDAC1,KCNA2,PRL,TNPO2,VPS33A,NCKIPSD,UBB,COX6B1,CAMLG,SEC22C,NDUFB6,ERP29,FGR,DUOXA2,MX2,UBE3A,COPE,MYO6,KCNF1,PEA15,DYNC1I1,CACNG3,SFT2D2,CD9,TRAPPC1,COX7A1,CPNE1,AQP4,SLC35A2,EXOC1,RHOBTB3,GUK1,DNM2,SLC38A7,SLCO1A2,ABCC2,ILDR1,SMURF1,EMP2,SRSF10,GJA10,LGI3,NDUFS3,KCNH1,SYN3,PMAIP1,SNAPIN,SLC32A1,CD36,TPT1,AQP2,SLC25A42,BCL2A1,TRAPPC6B,VAV2,TIMM29,CHMP2A,TSPAN18,SELENOS,UBXN6,DRD3,FTHL17,GABARAP,VPS26A,PHETA2,TBC1D4,CALHM2,P2RY4,LMNA,PEX26,FAM53B,IFT25,RALA,SLC1A1,KDELR2,CTNNB1,VPS26C,SLC1A2,HYAL2,CAMK2G,PACSIN3,VAMP1,TMC7,BOK,NPC1L1,CYB5A,SNX5,RAB5C,AP1M1,MAGOH,VDAC2,CARTPT,SLC8A1,SLC7A4,ATG4C,NUP50,ARRDC3,NUP153,ATP5IF1,CD14,SEC61B,TIMM8A,ADRB3,CCHCR1,GRIA1,SNX12,DERL1,GRID1,BAD,SLC4A8,BCAP29,CYB561D2,TUBA1A,ABCE1,RAB27A,SSX2IP,KPNA6,TEX261,HBM,TOMM40L,RAMP3,FAM91A1,GSK3A,STX7,NCALD,VLDLR,SLC41A3,ATP8A1,DDX39A,BCL2L1,APOC4,STXBP1,SEC14L1,NUP42,ARF4,TMEM165,RPS15,TLR4,TMEM14A,RPAIN,CLCA1,TMED7,GHR,LARGE1,SNX20,SLC15A1,HSPA8,ARHGAP1,TRAM1,RAB30,ITGAV,ACKR3,ANO3,CRABP2,TMEM38B,SLC25A39,NCBP2,LEPR,EHD1,CNP,GABRA1,KIF3B,RHCG,NDUFV2,STK4,UQCRH,STARD5,MAP1S,SLC7A9,TP53,PPFIA3,BET1,SLC16A1,SV2B,RBM15B,FCMR,SLC15A2,CHMP4C,SCFD1,CHMP5,FYTTD1,SLC25A12,APOO,TNFAIP8L3,MLC1,S100A6,CDO1,CD3G,CDKN1B,IPO8,SLC22A6,CYB5R1,B2M,RAB3C,GPM6A,CYP27B1,CDAN1,SLC35D1,APOC2,SNX2,SLC51A,KPNA2,GABRA2,SAMM50,MYO1B,SLC22A17,SMDT1,SNX22,TBC1D24,ARHGAP12,RNF5,PITPNA,CTDSPL2,HFE,CLDN4,RHOU,ARL4D,RAB11B,CDK5,KCNMA1,GOLPH3L,ELMO1,FGF7,SEC22A,RANGRF,ING1,ERLEC1,SLC25A4,AVPR1B,ANP32A,SEC13,ATP1A1,COX4I2,ATP6V0E1,RANBP6,PPT1,MUL1,XCL1,GRPEL2,VAPB,MAPKAPK3,ORAI3,ARF6,CASC3,AIF1,SLC25A27,EXOC3,RP2,GJA1,SEC61A1,MIR17,CKLF,TBC1D10C,SLC22A12,GPR89A,RSRC1,SLC25A5,LRRC8D,CITED1,NUP35,RAB31,TRAPPC6A,CDKN1A,RAB37,TOMM20,FOLR1,OPRM1,SLC48A1,RNASEK,STK3,CSF2,STX8,UNC119B,NDUFB7,ATP6V1D,SCG2,SLC6A7,LILRB1,YWHAH,RAB9A,NDUFS8,HNF1B,CCL3,NXT1,RAB18,ATP5F1A,CDC42,ICAM3,SOCS2,FTH1,GOSR2,CSNK1E,IFT172,SLC6A2,MTMR6,IGF1R,RTRAF,ARFIP1,RAB4A,ABCB9,KCNC1,FCHSD2,KCNB1,CCL5,TUSC3,ATP2C1,SLC25A51,CD81,AQP3,FXN,ATP5PO,SLC6A8,CCDC186,MYD88,NDUFC2,KLHL3,OPHN1,CYTH1,IFT22,HSPA5,VTI1B,COG1,SLC25A17,AP2M1,CSNK1G3,FURIN,CPTP,MFSD5,KCNAB1,CLIC2,TYROBP,C9orf72,PPY,TVP23B,SLC31A1,ELMO2,ADRB2,SRSF7,THOC3,CCR7,DHX9,VAMP8,KXD1,RAB1B,NAPG,RABL3,SLC7A8,ATP6V1C1,GAS8,CMTM6,RAB3B,TOMM22,KCNMB1,JAGN1,FBLN5,GJB2,SLC2A3,RAB29,GJB1,GABRG2,SYNGR2,OSBP,ATP5MG,LRP3,HRH2,PPFIA2,ALB,SLC35F2,LCA5,CD209,RAB13,KIF1C,RAB3A,SLC25A14,BECN1,TRAPPC3,LRRC8C,NAPA,POLA2,CBLN1,HBB,COX4I1,ERO1A,CCR5,OLR1,BAG3,CBL,NDFIP1,VTA1,GHRL,FCGR1A,VIPAS39,RABL2B,SLC66A2,WDR11,SYNGR1,JAKMIP1,RAB28,KCNIP2,SLC19A3,HGS,IRF8,CCR1,MRC1,CYTH2,OS9,NR1I2,COPZ2,SLC38A9,MIR29C,FKBP1A,CSE1L,PIK3CG,STX18,SLC6A11,PMP2,HNRNPA2B1,TRAPPC2L,PARP11,FASLG,ABCG2,HIKESHI,OLFM2,GTF2H2,NDE1,LRP10,CHTOP,NDUFB10,MAGOHB,PHAX,ZFAND2B,SYT2,COMMD9,P2RY12,THOC1,STX10,STAU1,SURF4,GPIHBP1,NEO1,NDUFS2,NUP107,RAB22A,NLGN1,CACNB2,IFT52,PAFAH1B1,ARFGAP3,CD47,PIK3CA,SLC13A5,ATP5PB,CRYM,NDUFB8,BET1L,BICD2,CAMK1,TIMM21,SLC52A3,STX17,FZD4,STIM1,NIBAN2,KCND3,MIR301B,IPCEF1,NDUFS6,CPLX1,RAN,PIK3R1,SLC6A6,ACAP2,TPD52,MTX2,WDR19,ATP6V1E2,PIK3R2,CUL3,AGK,PPM1K,FXYD6,SNX24,CTSA,VEGFA,BORCS7,SLC38A2,PRELID1,AP2S1,FABP5,NDUFB4,SEC62,TMED9,STX11,ZC3H11A,SELENOT,STX16,HDAC6,ZDHHC17,LIN7B,TESC,S100A8,DERL2,SCG5,RAB14,ARFGEF1,SYK,YKT6,NPC2,STAR,TIMM13,LACRT,RHOBTB1,SLC23A2,RAB33B,YES1,VMP1,ASIC1,NUP37,SCN3B,XPO1,SCYL2,ATRAID,SPTBN1,NAIF1,UBAP1,SLC2A1,BPGM,NPTX1,PPIF,VIP,STAT5A,DPP4,YIPF5,VPS54,TRMT10B,VAMP3,PICK1,RAB5A,FKBP4,GLRB,USE1,SLC12A2,SNAP23,STX6,HBE1,TIMM8B,ATP5F1D,DRD1,CHRM3,SLC16A10,CACNB4,NUP62,SLC35B3,ARL6,EXOC2,EHD3,TRAM1L1,TUBB,CBLN4,IGF2BP1,NHERF1,CLCN6,SLC16A4,NGB,SYNGR3,SYP,CLEC9A,CDC42SE1,MIR130B,BVES,OXSR1,MIA2,SNAP29,LMNB1,CALHM5,CLIP3,CA2,SLC37A4,MPV17,TMED1,VPS26B,AKT2,CEP19,CETN2,ACAA2,GNAO1,DDX39B,CHMP1A,UQCRC1,TRAF3IP2,BAX,EIF4E,GP9,TOM1L1,LAMP2,AHCYL1,IL6,FCER1G,KPNA1,SLC6A12,ARL11,SLC7A1,RAB23,SLC2A8,MACIR,G3BP2,BBS5,ACVR1C,DNAJC27,BORCS6,GPM6B,GLTP,LRRTM1,THOC6,TIMM17A,PPP1R10,FABP4,GRIA2,HM13,SYT4,SFN,SLC39A9,RHBG,AQP11,EHD4,KCNMB2,OCIAD2,MCL1,LEPROTL1,KCNIP3,PLCB1,ATG7,FAM53C,MLLT6,SCAMP2,SLC35C1,TRAPPC3L,PRKAG1,VPS18,OPTN,TAPBP,PNPLA8,CHMP2B,PEX5L,SAR1B,SLC35E1,EDNRA,TXNIP,XPOT,PAX6,VPS39,FKRP,SLC35F1,SLC25A31,SLCO3A1,AGR2,TMED4,KCND2,AKT1,AIFM1,SLC45A3,CEBPE,WNT7A,PPP3CA,SLC6A1,ARFGAP1,MT3,ATP5PD,OXTR,RAB3D,DYNC1I2,RHCE,MAP1B,VDR,RHAG,BAK1,SNX18,ABCB1,ATP6V1G2,CALR,NSG1,ROMO1,NFKBIA,UCP2,SLC18B1,ENY2,RFTN2,SYNRG,SOD1,LAT2,LMBRD1,CCND1,TGFBR2,SLCO2B1,SLCO1B3,KIT,XBP1,CYB5R4,KCNK17,FHIP1B,MET,CPE,LASP1,SYVN1,ATP5MC1,SLC25A10,CPLX2,PRKCE,SLC25A26,PLA2G5,KCNH8,PCSK9,TFG,PIP5K1A,KCNK13,KCNS1,TSG101 |
| 1.903e-08 | -17.78 | SF3A3 (splicing factor 3a subunit 3) | protein interactions | 10946 | 289 | 125 | 19454 | 5460 |
ZDHHC17,STAU1,UFL1,TRA2B,SRSF2,EP300,PSMA3,HSPA8,SF3B1,NKAPD1,DDX39B,SNRPA,VAV2,KCTD12,ESR2,SNRPB2,MAD2L1,SNRNP40,MATR3,GTF2F1,SNRPD2,SF3B4,PRMT5,SNRPD1,RIT1,BRCA1,PSMD14,MCM4,CCDC85B,TTC33,SNRPB,PRPF31,CUL3,HNRNPC,MYC,RAD21,MCM6,MIR155,KRAS,BAG2,MIR206,TRIM21,HNRNPA2B1,HSPD1,HGS,SNRPE,SF3B5,SMNDC1,SKA3,ACTN4,DHX15,SNRPA1,SNRPD3,MIR214,MIR141,EED,RBM5,ANXA4,SRSF1,HSPB1,MIR221,DDX23,HNRNPA1,IFI16,PRPF19,MIR107,FBXW7,KDM1A,MIRLET7I,PRPF4,RPA3,BAP1,DDX46,MIR7-1,HEXIM1,CDAN1,HNRNPH3,TFIP11,IDH2,METTL14,RPA2,TOX4,PTP4A2,SNRPN,MIR34B,SF3A1,VIRMA,SF3B6,UBE2H,RBM7,EPHA2,MIR145,DNAJC8,USP14,SNRPG,MEPCE,TTC4,CTNNBL1,LSM4,HUWE1,EMC2,HAPSTR1,SNIP1,MIR200A,DDX42,ACTR1A,CD2BP2,MIR200C,CWC15,CDC5L,MIR429,CDK9,MIRLET7G,RPL35A,CAND1,RCHY1,UBE2N,MIR106B,MIR34A,SMCHD1,SNRNP70,CRBN,COPS5,RBM17,CALR |
| 1.914e-08 | -17.77 | TMEM216 (transmembrane protein 216) | protein interactions | 51259 | 244 | 109 | 19454 | 5460 |
DDRGK1,WDR11,OSBP,NUP35,WDR6,STX5,VAMP2,STIM1,CYB5B,PLD3,STX12,MACO1,MARCKSL1,TOP3B,SLC20A2,EMC8,RETREG1,TMEM87A,SEC11A,EFNB1,SLC39A7,SPCS3,VMP1,SCFD1,SLC38A1,VEZT,SLC30A5,MB21D2,ATP6AP2,CHP1,FAM91A1,GPR89A,FZD6,TMEM115,VAPB,ARCN1,TOR1AIP2,BET1,RER1,GOSR1,EMC1,STX7,JAGN1,BET1L,ESYT1,POR,AGPAT1,OSBPL8,DHRS7,TMEM199,RELL1,DNAJC1,ARL6IP5,CAV1,CD99L2,SLC38A2,STX6,TMPO,LMAN1,CAMLG,UBE2G2,SRPRA,PTPN1,CDCA3,SLC39A10,TFRC,PREB,CCDC47,UBIAD1,LBR,SRPRB,FKBP8,CTNND1,SLC6A8,NSDHL,STX8,EMC2,SNAP23,STX18,ABCE1,ARFGAP3,EPHA2,GORASP2,SLC6A6,HMOX2,F11R,SEC63,VKORC1L1,NECTIN2,VAMP3,STX10,SLC12A2,TMX4,USE1,SSR1,GOLGA5,LEMD3,PDCL,SEC22B,ARHGAP1,RABL3,YKT6,CERS2,TMEM209,TEX264,ARFIP1,RTN4,MTDH,SPCS2 |
| 1.914e-08 | -17.77 | MTHFD1 (methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1) | protein interactions | 4522 | 244 | 109 | 19454 | 5460 |
ZBTB2,CAV1,DCUN1D1,RPL35A,RPS16,CD274,RCHY1,RPL32,DNAJC7,SNRNP70,CD81,HDAC6,FBXO25,PC,MAP1B,SNIP1,SFXN1,MRPL49,ACTR2,TMEM165,MAP1LC3B,GGCT,KBTBD4,TP53,VIRMA,TXN,KCTD9,PTEN,PSPC1,CCNF,CDC73,UBE2H,EIF3G,TRIM23,TXNIP,FBXO7,NONO,USP14,MAT2A,PTPN11,POLDIP2,STK38,FBXW7,SQSTM1,RNF113A,BAP1,DVL2,MME,RPA3,SOD1,PML,NLE1,RPLP0,HEXIM1,RPA2,CFTR,SUMO1,EGLN3,CCT7,HSP90AB1,RPL7,SUMO2,PHB1,AGR2,TRAF6,FKBP4,ATG7,CTNNB1,PRPF19,WWP2,PSMD12,SAR1B,PAK6,CA10,G3BP1,KRAS,HNRNPF,XPNPEP1,TRIM21,HNRNPA2B1,MOB3C,PLS3,EZH2,ISG15,FAF2,RAF1,ESR2,MRPL23,FBXO22,PRMT5,PAPSS2,COP1,HSP90AA1,HTRA2,RIT1,ATG3,BRCA1,MYC,CUL2,PAPOLA,CUL3,UFL1,ADRB2,HDAC5,CRY1,HSPA8,PSMA3,PIH1D1,NEK7 |
| 1.923e-08 | -17.77 | Measles | KEGG pathways | ko05162 | 133 | 77 | 7161 | 2463 |
IFNA13,IL1B,CD28,CCND3,HSPA8,PIK3CA,IRF7,IL2RB,TLR2,PIK3R3,TAB2,RAB9A,RIGI,TBK1,MX1,EIF2S1,CD46,STAT5A,CDK4,STAT1,AKT2,FASLG,TLR4,IFNAR1,CCND1,NFKBIB,IFNGR1,IL12B,RAB9B,PIK3R2,TLR7,IRAK4,AKT1,IL2RA,IL4,JAK2,PIK3R1,IRF9,OAS1,IL6,IL1A,TACR1,CDKN1B,SH2D1A,CD209,CSNK2B,TLR9,MYD88,IFNB1,AKT3,TNFSF10,FAS,IL2RG,MSN,NFKB1,IFNA10,TNFAIP3,CSNK2A1,RCHY1,IFIH1,STAT2,TRAF6,JAK1,IFNA2,PRKCQ,FCGR2B,CD3G,IL13,IRF3,NFKBIA,IL12A,IL2,EIF2AK2,TP53,IFNG,CDK6,MAVS |
| 1.923e-08 | -17.77 | Measles | KEGG pathways | hsa05162 | 133 | 77 | 7161 | 2463 |
PIK3R2,IRAK4,TLR7,AKT1,IL2RA,JAK2,IL4,PIK3R1,IRF9,OAS1,FASLG,TLR4,IFNAR1,CCND1,NFKBIB,IFNGR1,IL12B,RAB9B,RAB9A,RIGI,TBK1,MX1,EIF2S1,CD46,STAT5A,CDK4,STAT1,AKT2,IFNA13,IL1B,CD28,CCND3,PIK3CA,HSPA8,IRF7,IL2RB,TLR2,PIK3R3,TAB2,TP53,IFNG,CDK6,MAVS,JAK1,IFNA2,PRKCQ,CD3G,FCGR2B,IL13,IRF3,NFKBIA,IL12A,IL2,EIF2AK2,MYD88,IFNB1,AKT3,TNFSF10,FAS,IL2RG,NFKB1,MSN,IFNA10,TNFAIP3,CSNK2A1,RCHY1,IFIH1,TRAF6,STAT2,IL6,IL1A,TACR1,CDKN1B,SH2D1A,CSNK2B,CD209,TLR9 |
| 1.925e-08 | -17.77 | PGRMC1 (progesterone receptor membrane component 1) | protein interactions | 10857 | 358 | 149 | 19454 | 5460 |
SEC63,VIRMA,UBB,TECR,RPS20,UBE2H,DNAJC19,NRP1,CIAO1,GORASP2,DAD1,RAB29,GID8,BAP1,NCDN,RPA3,CYP2C18,RTN4,RAB9A,DERL1,SPCS2,FGFR1,SSR1,RPA2,CDK1,LMNA,ACACA,PCK2,ST7,NTPCR,CFTR,CDC42,ARF6,TMED9,DNAJC1,TMPO,EPHB6,LMAN1,CAMLG,RCHY1,HACD3,STT3A,COQ8A,PTPN1,HSD17B11,ESYT1,POR,OSBPL8,ADIPOR2,EMC4,PGAM1,DPP4,COPS5,LAMP3,SRPRB,TMEM33,RAB3B,RDH11,RNASEL,FKBP8,PSEN1,RNF20,DUSP21,SFXN1,BCAP29,HSD17B10,EMC2,SLC6A3,STX18,FURIN,CDK4,CCDC47,KBTBD4,UBL4A,LBR,MAD2L2,USP5,PIGK,LMBR1L,SEC61B,LMNB1,SPCS3,FAS,ARHGAP19,CKB,ZMPSTE24,VMP1,SCFD1,CUL3,OST4,TMEM213,ADRB2,TMED3,RER1,SSR3,UFL1,PXMP2,COIL,FOS,DUSP9,PMAIP1,MED23,VAPB,BET1,EFHD1,DUSP22,SEC62,PPP1CB,OSBP,PCSK9,NUP35,EGLN3,PHB1,RAB35,STX5,CYB5A,RB1CC1,PTPN5,RAB5C,LAMP2,DDRGK1,FAM241A,ACVR1B,VDAC1,EMC8,KRAS,ARHGAP15,TMED7,RINT1,TMT1A,DEFB124,CYP2C9,CYP1B1,SCD5,CDK5,DNAJB4,PTRH2,RAB4A,RPN1,CYP2C8,EZH2,STIM1,MOB3C,OTULIN,RAF1,TOP3B,ERLIN2,CCDC134,DNAJC25 |
| 1.979e-08 | -17.74 | spliceosomal complex | cellular component | GO:0005681 | 202 | 96 | 19108 | 5553 |
PPIL3,PPWD1,HNRNPF,SNRPD1,SNRPB,CDC40,SNRPA,MAGOHB,LSM5,SCNM1,TXNL4A,SNRPN,ZMAT2,TSSC4,DDX5,PPIH,RBMX2,SMU1,HNRNPA1,RHEB,SNRPA1,SF3B6,TRA2B,BUD31,CWF19L1,SNRPB2,CDC5L,CWC15,SNRPG,PRPF4,AKAP17A,RBM3,LGALS3,CASC3,SF3B4,SF3B5,SF3A1,SNRNP40,GCFC2,ALYREF,DHX15,SLU7,SNIP1,RNF113A,PABPC1,SNRPD2,LSM6,DDX39B,PRPF31,DHX38,API5,LUC7L3,CIRBP,SYNCRIP,LSM4,HNRNPA2B1,LSM3,DDX46,SNRPD3,CTNNBL1,SRSF2,SNRNP48,ESS2,HNRNPK,SF3B1,HNRNPC,LSM2,HSPA8,SRSF1,EIF4A3,ZCRB1,USP39,KHDC4,IK,RBM41,MAGOH,SUGP1,DDX42,LSM8,PRPF18,HNRNPH3,RBM5,ARMC7,DDX23,ZMAT5,SNRNP70,TRA2A,IVNS1ABP,TFIP11,MFAP1,PPP1R8,DHX16,WDR83,SNRPE,PRPF19,RBM22 |
| 2.069e-08 | -17.69 | MTG2 (mitochondrial ribosome associated GTPase 2) | protein interactions | 26164 | 278 | 121 | 19454 | 5460 |
NDUFS3,MRPL49,CD14,ATP5PB,NDUFA2,MRPL47,MRPL11,PPIF,HADH,MGARP,METTL15,BCS1L,PDE12,MRPS33,HSPE1,MRPL22,FKBP8,MRPL52,ATP5PF,MRPS18B,HSD17B10,GRSF1,COX5A,MRPL50,DBT,ATP5PD,MALSU1,MRPL24,MRPS23,MRPS9,ALYREF,PREP,MRPS34,QRSL1,LEMD3,COQ8B,MRPL10,MRPL17,NME4,PDHB,MRPL41,MRPL40,GRPEL1,CRYZ,POLDIP2,MRPL20,IDH3A,AMACR,TWNK,DLAT,GFM1,MRPS16,OAT,NDUFAF2,PYCR2,NTAQ1,TUFM,INPP5K,MRPS28,ACAT1,NUDT19,NDUFS6,PDHA1,NDUFA12,TOP3B,ETFB,KRAS,USP30,ATP5F1D,ETFA,KGD4,MRPS17,HNRNPDL,HSPD1,PREPL,BCKDK,HINT2,MRPS11,MRPS26,ARMC8,LAMP2,CLPX,PFDN5,MRPS35,STOML2,NDUFV2,MRPL9,ATG7,MMUT,CBR4,HNRNPL,NDUFS8,PHB1,HDHD5,FAHD1,ATP5PO,NDUFA5,TOMM22,NDUFAF3,MRPL12,NDUFS2,MRPS7,ATP5IF1,HADHA,LMNB1,MRPS25,AUH,PYCR1,MRM2,PMPCA,HNRNPAB,MRPL16,TOMM40,PCCB,ATP5F1B,MRPL23,TAB1,NDUFAF4,TACO1,DLST,MRPL13 |
| 2.072e-08 | -17.69 | UQCRB (ubiquinol-cytochrome c reductase binding protein) | protein interactions | 7381 | 121 | 63 | 19454 | 5460 |
SLC25A24,NDUFA12,NDUFS3,MAGEA4,ACCS,COX4I2,ATP5PB,PSMB10,VDAC1,S100A10,KRAS,NDUFA4,RPL23,NDUFB8,HSPB1,RPS2,TMEM70,SMAD4,CTNNB1,ATP1B1,RPL6,COX5A,SLC25A17,ATP5PD,UQCRH,MYL12A,ESD,RPS16,RPS10,FZR1,COX4I1,PHB1,NDUFB4,SDHB,RPL9,CYC1,PRKCA,COX7B2,MAP2K1,BORCS6,UQCRC1,TIMM10,HSPA5,PDHB,HSPA8,SPECC1L,GRAMD2B,RIT1,AP2A1,NRP1,ZSWIM7,ATP1B3,ATP5F1A,HPCA,COX6B1,PARL,VIRMA,GNB1,UQCRQ,ACTB,PTPMT1,ACAT1,UQCRC2 |
| 2.072e-08 | -17.69 | Eif3a (eukaryotic translation initiation factor 3, subunit A) | protein interactions | 13669 | 121 | 63 | 19454 | 5460 |
TRMT112,LARP4B,EIF3J,RPS14,RPL27A,H1-5,BRIX1,EIF4E,RPL4,NPM3,EIF5B,RPS15,EMG1,RPS28,RFC4,RPL27,EIF3G,ASCC1,RPS29,RPL7A,RPL22,RPL19,RPL10,PRRC2A,RPL13A,ZNF622,EIF4A2,RPS12,RPS20,EIF3K,RPS3,FAU,CCNF,SRP72,RPS11,EIF1AX,RPSA,EIF3E,RPL17,G3BP1,HSD17B10,RTCB,RPS24,RPL23A,RPL3,PPAN,RPL10A,RPS2,DDX1,RPL24,MPG,EIF3D,BAZ1B,LYAR,RPL7,FAM98A,RPS10,RPS16,RPL35A,HP1BP3,RPL32,SRP14,RPL8 |
| 2.094e-08 | -17.68 | MTIF2 (mitochondrial translational initiation factor 2) | protein interactions | 4528 | 341 | 143 | 19454 | 5460 |
TMEM70,SLC2A1,SMAD4,ATP5MG,COX5A,NFKB1,GRSF1,LYPLAL1,MRPL50,MRPL24,MRPS23,MALSU1,DBT,ATP5PD,COX4I1,AIFM1,SSBP1,MRPS9,NDUFS3,NUDT16,MRPL49,MRPL11,MRPL47,NDUFA2,ATP5PB,BCS1L,METTL15,HADH,PPIF,KPNA2,RASL10B,MRPS33,PDE12,RIGI,MRPL22,FASTKD5,MRPS18C,ATP5PF,HSD17B10,CLPB,MRPS18B,MRPS16,OAT,PYCR2,NDUFAF2,TUFM,MRPS21,MRPL53,ACAT1,MRPS28,QRSL1,LDHAL6B,MRPS34,METTL2A,MTRES1,CNP,NDUFAB1,MRPL10,MRPL40,MRPL41,MRPL17,PDHB,NME4,POLDIP2,MRPL20,CRYZ,GRPEL1,AMACR,GFM1,DLAT,TWNK,RHOG,IKBKB,HSPB1,MRPS26,MRPS35,STOML2,PFDN5,CLPX,MTRF1,CBR4,MMUT,NDUFV2,MRPL9,HNRNPL,EIF2S1,PNPLA8,DIRAS3,NDUFS8,GATD3,FAHD1,YBEY,PDHA1,NDUFS6,NUDT19,NDUFA12,ETFB,HSDL2,KGD4,ETFA,ATP5F1D,IMMP2L,HNRNPDL,MRPS17,BCKDK,PREPL,HSPD1,MRPS11,COX8A,HSD17B8,HINT2,NOA1,CHTOP,MRPS25,MRM2,PYCR1,PMPCA,AUH,MTG2,MRPL16,MRPL23,ATP5F1B,NDUFAF4,NFKBIB,CCDC90B,MTG1,DLST,TACO1,MRPL13,ACAA2,ATP5PO,MRPS18A,NDUFA5,MRPL12,PRDX3,MRPL57,HSCB,NDUFS2,MRPS7,SKP1,EXD2,NGRN,HADHA |
| 2.134e-08 | -17.66 | POMP (proteasome maturation protein) | protein interactions | 51371 | 63 | 39 | 19454 | 5460 |
PSMB2,PSMA4,FAM107A,ARMT1,PSMG3,FAS,PSMG2,POMP,MPPED2,DSTN,IGBP1,PSMB1,PSMA6,PSMB5,RBM5,PSMB4,EGLN3,PSMB6,PYGM,CD2BP2,PSMB9,CNPY3,UBE2V1,FAM89B,TP53,PSMB3,PSMC3,PSMB7,PSMG4,PSMA3,DCTN3,TFPT,UBE2A,PSMB10,CPLX1,PSMA5,PSMA1,PSMA2,SEM1 |
| 2.134e-08 | -17.66 | LSG1 (large 60S subunit nuclear export GTPase 1) | protein interactions | 55341 | 160 | 78 | 19454 | 5460 |
STIM1,RPN1,PTRH2,DISC1,DNAJC2,FURIN,SRP72,RAF1,TP53,DNAJC25,KRAS,DNAJC30,FKBP8,IMMP2L,TMT1A,DEGS1,RHOG,ESYT1,SNRNP70,UQCR11,DRG1,MOV10,SLC25A46,YWHAH,DDRGK1,RPS16,DNAJC1,CGAS,LMAN1,TMPO,EGLN3,PTPN1,ARL10,HSD17B11,KRT8,PLPPR1,VAPB,LMNA,SSR1,VPS18,FGFR1,EHHADH,TPT1,OTULINL,SEC62,ST7,PSENEN,RPL4,STAU1,TOMM20,PXMP2,STX7,SYVN1,RAB5A,EP300,DERL1,RAB9A,LMNB1,ATG3,NTRK3,NRP1,FIS1,DNAJC19,UBE2H,HTRA2,MYC,ANAPC15,ZNF622,SPCS1,RPL19,RPL10,VIRMA,ESR2,SEC63,PSPC1,METAP2,GSK3A,SEC61B |
| 2.191e-08 | -17.64 | Ubiquitin-dependent degradation of Cyclin D | REACTOME pathways | R-HSA-75815 | 52 | 36 | 10285 | 3229 |
PSMA4,PSMC5,PSMB11,PSMA5,PSMB10,PSMA2,PSMB6,PSMD1,PSMB2,PSMB3,PSMA6,PSMD3,PSMB7,PSMB1,PSMA3,PSMB5,PSMD12,PSMC1,CDK4,PSMC4,PSMD14,PSMC3,PSMA1,UBA52,RPS27A,UBB,PSMD4,PSME2,PSMD10,PSMD6,PSMB4,CCND1,PSME1,PSMB9,SEM1,PSMD7 |
| 2.191e-08 | -17.64 | Ubiquitin-dependent degradation of Cyclin D1 | REACTOME pathways | R-HSA-69229 | 52 | 36 | 10285 | 3229 |
PSMB5,PSMA3,PSMD12,PSMC1,CDK4,PSMC4,PSMD3,PSMB7,PSMB1,PSMA2,PSMB6,PSMB2,PSMD1,PSMB3,PSMA6,PSMA4,PSMC5,PSMB11,PSMA5,PSMB10,PSMB9,SEM1,PSMD7,PSMD10,PSME2,PSMD6,PSMB4,CCND1,PSME1,UBA52,RPS27A,UBB,PSMD4,PSMC3,PSMD14,PSMA1 |
| 2.243e-08 | -17.61 | GANAB (glucosidase II alpha subunit) | protein interactions | 23193 | 350 | 146 | 19454 | 5460 |
ARCN1,ARMCX3,PSMB7,NEK7,EDEM3,DUSP22,RND2,PAFAH1B1,PXMP2,DUSP26,STAU1,EMC1,UFL1,NPTN,EP300,AKAP1,PSMA3,HSPA8,HDAC5,TMEM106B,XRCC5,DNAJC3,BRCA1,RHOB,CCT2,ARHGAP19,MCM4,SAMHD1,TOMM40,CUL3,PSMA4,MYC,PRRC2A,ESR2,PSMD6,TAB1,MATR3,MTM1,SEC61B,PRMT5,RMDN3,VDAC2,LMBR1L,RHOBTB1,PLD3,RND3,CHMP4C,EZH2,PLS3,DNAJC25,ISG15,PPP2R1A,E2F4,SUPT5H,PI15,B3GNT2,SAR1B,MCM6,ASB7,POU5F1,TRAF6,AGR2,CTNNB1,MRPL9,EGLN3,TCP1,RHOH,DNAJB9,PHB1,SWAP70,ACACA,HSP90B1,GRM2,METTL14,RPA2,JUP,DCTN4,CFTR,CDK7,GABRA1,CCNH,CDC42,BCL6,HSPA5,PIAS1,FBXW7,SMC4,DERL1,ACP5,CST11,SIRT7,SOD1,RPA3,BAP1,RHOU,UBE2H,CALU,IVNS1ABP,DNAJC10,STK24,SLC25A1,VIRMA,DEK,CTTNBP2NL,ADRM1,RPGRIP1L,RHOJ,CTSB,COPE,MSN,DNASE1L1,CCNF,UQCRC2,CREB3L4,HSPA13,TFRC,ACTR1A,H2AX,TP53,RAP1A,CCT5,DUSP19,MSH6,DUSP21,KPNA2,DNAJC30,PSMA5,HUWE1,EMC2,IGF1R,PSME1,ZDHHC15,TUBG1,HDAC6,CSNK2A1,FAM20C,DPP4,CALR,TMPO,CDK9,PRNP,DNAJC1,ASB11,RAC2,COX4I1,CD274 |
| 2.297e-08 | -17.59 | IGSF8 (immunoglobulin superfamily member 8) | protein interactions | 93185 | 228 | 103 | 19454 | 5460 |
H1-1,KDSR,SNRPB,MBLAC2,RBBP4,TUBB,RPL35,RPL19,EIF3K,FAU,LMBR1L,RPS9,SNRPD1,RPL27A,EEF1G,FTL,TSPAN15,RPS28,XRCC5,TMEM160,DDX5,H2BC17,TMEM30A,HNRNPD,RPL6,IFI16,HNRNPA1,SNRPD3,SNRPA1,DHX15,RPL8,RPL9,DNM2,RPLP2,NRSN1,H2BC1,SART3,RPS23,RPL18,H1-3,TUBA1A,ACTN4,ANP32B,RPS4X,HNRNPA2B1,PABPC1,RPL31,PDIA6,SRSF8,EIF3G,ATP1B3,PDCD4,RPL7A,AKT1,CFL2,H2BC9,CFL1,RPL26,RPL13A,VIRMA,RPL22,TUBA1B,RPS3,MSN,GHITM,TMX4,H2BC11,RPL26L1,RPLP0,RPS14,FTH1,RPL4,RPS15,ITM2B,NCDN,RPL27,H2BC12,CD9,RPL24,LSM3,RPS2,CD81,CSNK2A1,EIF2B5,EIF2B2,RPS16,RPL35A,ALYREF,RPL12,SRP14,SYNCRIP,EEF1B2,CTLA4,ILF2,SERPINB9,HNRNPK,H2BC14,RPL17,EIF3E,RPS13,TCOF1,RPL23A,BSCL2 |
| 2.323e-08 | -17.58 | RAD23A (RAD23 homolog A, nucleotide excision repair protein) | protein interactions | 5886 | 217 | 99 | 19454 | 5460 |
USP5,PSMB6,PSMD6,PSMD4,DLG4,MYO6,PSMD14,PSMD1,TBCE,CDKN3,PSMA4,USP13,CREBBP,RNF41,PSMC1,SRSF2,EP300,PSMA3,HSPA8,TXNL1,XRCC5,PSMB7,VAV2,PSMB3,CETN2,CNTROB,SUMO3,MAP1LC3A,PSMB4,PSMB5,HSPB1,TRAF6,NT5C2,TRIM8,WWP2,PRDX1,PSMD3,PSMD12,DCTPP1,RPS27A,PSMA2,PSMA1,UBE3A,PCNA,EWSR1,RPN1,EEF2,TRAF2,ISG15,HEXA,UBB,SMURF1,ADRM1,TRIM54,TMOD3,GNPDA1,PHAX,PSMC5,PSMA6,HERC4,SORD,PTTG1,ZFAND6,LACRT,USP14,PSMB2,TNFAIP3,MEA1,SQSTM1,CCNA2,GTF3C4,UBA52,TPT1,PSMC4,MDM2,PRNP,PLEKHF2,PSMB1,ARL4D,UBE2N,PSMD7,BECN1,MPG,RIGI,PSEN1,NEDD8,SEM1,RNF115,LSM4,HUWE1,PSMA5,FAF1,PDE6D,PSMC3,RAD23B,ZBTB26,MINDY3,EEF1A1,TP53 |
| 2.325e-08 | -17.58 | PSMB3 (proteasome 20S subunit beta 3) | protein interactions | 5691 | 187 | 88 | 19454 | 5460 |
SKP1,DDI1,PSMC1,PSMA3,DDX39B,PSMB7,PSMB3,PSMB6,MBL2,PSMD6,PSMD4,RIT1,PSMD14,POMP,CPSF2,BAG3,PSMD1,PSMA4,MYC,RPS27A,PSMD12,PSMA1,KRAS,PSMA2,UBE3A,SART3,DSTYK,ISG15,SOX2,TRAF2,NUP35,SNRPA1,PSMB5,PSMB4,PSME2,AGR2,KDM2A,PSMD10,ELP6,NCR3LG1,DDRGK1,PSMD3,MPZ,DESI1,PSMG4,SYVN1,BAP1,RPA3,HEXIM1,METTL14,OSER1,SDCBP,RPA2,CFTR,PAAF1,PRMT2,PSMC4,SF3A1,VIRMA,ADRM1,TRIM27,PSMC5,PSMA6,PSMG3,SPOP,AR,USP14,FBXO7,PSMB2,CAPZA1,FKBP8,PSMB10,PSMA5,H3C1,ABCE1,PSME1,PSMC3,RAD23B,RNF181,H2AX,PSMB9,INSIG2,TP53,PRNP,FZR1,PSMB1,PSMD7,PSMG2 |
| 2.376e-08 | -17.56 | CLASP2 (cytoplasmic linker associated protein 2) | protein interactions | 23122 | 129 | 66 | 19454 | 5460 |
RPL15,ACTR1A,RAF1,TOP3B,CYB5B,OTULIN,PPP4C,PNMA2,TUBB4B,HAPSTR1,TRIP4,RAD21,PSMA5,DDRGK1,MPG,YWHAG,CSNK2A1,XPO1,YWHAH,MOV10,YWHAB,SNRNP70,POR,FEZ1,ARL10,CD274,DYNC1I2,MAPRE2,HNRNPL,FZR1,FAXC,PAFAH1B1,ATG16L1,RBFOX2,TRIM36,LXN,RPA2,JAKMIP1,BAP1,RPA3,HSPA5,ASB3,CCR4,ADRB2,STAU1,PSENEN,ANAPC15,CSGALNACT2,SFN,TAF5L,CREBBP,AKT1,MAPRE1,UBE2H,PEA15,YWHAZ,RC3H2,GSK3A,FAM43A,CCNF,VIRMA,ESR2,SRPK2,SMURF1,FBXO22,PYGM |
| 2.428e-08 | -17.53 | RRBP1 (ribosome binding protein 1) | protein interactions | 6238 | 290 | 125 | 19454 | 5460 |
ATP5F1A,H2BC9,USP14,EMILIN1,CSK,PTPN11,UBE2H,MAPRE1,SPOP,GSK3A,CCNF,MRPL53,PSPC1,VIRMA,SEC63,CDC42,CFTR,ST7,METTL2A,RPA2,SSR1,WWP1,RNF113A,MTDH,DERL1,RAB9A,SQSTM1,RPA3,PML,BCL6,GRSF1,SLC25A46,RPL10A,DSTN,HSD17B11,RAC2,PTPN1,RBM42,TMPO,CDK9,RPS16,DNAJC1,FZR1,CGAS,EEF1A1,AURKAIP1,PPIF,FBP1,CCDC47,MTCH2,ZNF513,SRP72,DISC1,DNAJC2,RAB1A,PPP1R12A,PQBP1,FKBP8,RIGI,H3C1,RAB3B,SRPRB,BTF3,MYC,CUL3,PSMA4,RAB11A,SEC61B,VDAC2,DLST,MATR3,FBXO22,RND2,PPP1CB,OTULINL,SEC62,TOMM22,BET1,EIF4B,FEM1A,PCLAF,HSPA8,RAB5A,PXMP2,STX7,G3BP2,UFL1,EEF1G,STAU1,MAP3K14,DDRGK1,SYNJ2BP,WWP2,SMAD9,RB1CC1,ARMC8,DRG1,RHOG,FKBP4,AGR2,MAP1LC3A,RPL8,PHB1,HSP90AB1,CHMP2A,HSBP1,HNRNPL,BUD31,DNAJC25,LGR4,RAF1,B3GNT2,TXNRD1,EZH2,STIM1,RPN1,PLS3,SMNDC1,PDHA1,EWSR1,MORC2,RPL31,HNRNPA2B1,TMT1A,HNRNPDL |
| 2.437e-08 | -17.53 | SUGP2 (SURP and G-patch domain containing 2) | protein interactions | 10147 | 198 | 92 | 19454 | 5460 |
MIR106A,B9D2,STAU1,SLC25A3,LARP4B,TIMM10,PABPC5,MIRLET7D,ESR2,MATR3,SNRNP40,FOXP3,ATXN1L,MIR363,FAM83A,ZNF668,MYC,HNRNPC,SSRP1,G3BP1,MIR155,MIR206,RUVBL2,SRSF7,FHL3,MIR222,SOX2,TOP3B,RAF1,PAIP1,HNRNPL,MIR9-1,MIR141,MIR214,MIR7-2,MIR1-1,MIR221,CPEB1,MIR29C,HNRNPA1,MIR143,MIR29A,MIR107,FBXW7,MIRLET7I,TMEM126B,RPA3,SIRT7,MIR205,RPLP0,MIR21,MIR7-1,RPA2,MIR1-2,RBMS2,CDK7,MIR34B,CCND1,VIRMA,COPE,FGFBP1,GSK3A,PTEN,MIR16-1,ELAVL2,UBE2H,RC3H2,AR,NONO,CSK,NDUFAF2,MIRLET7C,MIR16-2,DHX9,MIR9-3,SNIP1,ILF2,MIR17,CDK8,MIR20A,APOBEC3D,MIR200C,EXOSC8,KBTBD4,MIR429,MIRLET7G,PRR3,MIR25,ARL4D,MIR106B,TUBG1,MOV10 |
| 2.437e-08 | -17.53 | GSTP1 (glutathione S-transferase pi 1) | protein interactions | 2950 | 198 | 92 | 19454 | 5460 |
YWHAZ,HSP90AA1,CUL3,PMPCA,CUL2,ACO2,MYC,LGALS3,PRDX2,ESR2,CLIC4,KRTAP3-1,DLST,PPT1,ARCN1,LAP3,PTN,UFL1,ARL6,GSTT2B,DDX39B,JADE1,APPBP2,TXNL1,AGR2,GSTO1,BCL2L1,YWHAB,CBL,DCAF4L2,PRDX1,DDRGK1,HNRNPA1,GATD3,GJA1,NGB,EZH2,FEN1,TRAF2,SOX2,ISG15,UBE2A,HINT2,DNAJB4,FXN,VAMP5,GORASP2,MTPN,CTSB,TXN,VIRMA,ENO1,ZNF655,ABHD14B,ZBTB18,IDH2,RPA2,LMNA,E2F6,HEXIM1,UBE2M,GSTP1,SPR,TXNL4A,FBXL19,NDUFAB1,CRYZ,POLDIP2,NBN,SIRT7,PNO1,INPPL1,SOD1,BAP1,PRDX6,SQSTM1,COX5A,HDAC6,COPS5,COX4I1,ACTA2,GABPB1,RNF8,SH3GLB1,TRIM6,CMPK1,PGM1,TMSB10,GLRX5,HNRNPK,MPST,RIGI |
| 2.442e-08 | -17.53 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | REACTOME pathways | R-HSA-174178 | 73 | 46 | 10285 | 3229 |
PSME1,PSMD10,PSMD7,PSMD14,UBB,CDC26,UBA52,CDC20,PSMB1,CDC16,PSMD3,PSMB7,PSMC4,PSMB5,PSMA3,PSMB11,PSMC5,PSMA5,PSMB10,PSMA4,PSMB3,PSMB6,PSMA2,PSMD6,ANAPC2,ANAPC15,CDC23,PSMB4,UBE2D1,PSME2,PTTG1,ANAPC4,FZR1,PSMB9,SEM1,PSMA1,PSMC3,PSMD4,ANAPC11,RPS27A,PSMD12,PSMC1,ANAPC16,PSMA6,PSMD1,PSMB2 |
| 2.492e-08 | -17.51 | MRPL13 (mitochondrial ribosomal protein L13) | protein interactions | 28998 | 220 | 100 | 19454 | 5460 |
TMEM70,CHCHD1,SNRNP70,GLO1,MOV10,GRSF1,MRPL24,MALSU1,MRPL50,PRR3,RPL32,MRPS9,SSBP1,MRPL49,MRPL51,MRPL33,GFM2,NDUFS3,GINS4,METTL15,AURKAIP1,APOBEC3D,MRPL47,MRPL11,RPL17,MEPCE,MRPL22,FASTKD5,RPL3,RPL23A,MRPL52,DNAJC19,UBE2H,TUFM,RPL26,NDUFB10,RPL13A,MRPS28,MRPL53,MTRES1,ZNF574,RBMS2,MRPL10,MPV17,MRPL20,RPL4,MRPL41,MRPL40,MRPL17,GFM1,PPM1K,MRPS26,MRPL18,SKIC8,RHOG,MRPL9,HNRNPA1,RPL6,MTRF1,SRSF10,LYRM2,RPL7,GATD3,FAHD1,RPL18,PDHA1,PPP2R1A,NUP42,SRSF7,HINT2,PPAN,RPL31,HSPD1,SCFD1,FBXW11,MRPL16,BTF3,CUL3,PMPCA,MTG2,MYC,AUH,RPL19,ESR2,RPL10,RPL35,MRPL23,RPS9,MTG1,TACO1,SLC25A3,MRPS18A,MRPL12,DHRS4,RPL27A,MRPL57,HSCB,MRPL34,EXD2,NGRN |
| 2.526e-08 | -17.49 | VPS13D (vacuolar protein sorting 13 homolog D) | protein interactions | 55187 | 61 | 38 | 19454 | 5460 |
YWHAB,FIS1,PEX3,YWHAZ,PSMD14,YWHAH,YWHAG,MARCHF5,SLC25A46,VIRMA,FBXO22,RHOH,MGST3,RAC2,GSK3A,TSG101,RMDN3,PTPN1,AIFM1,RAB4A,PTRH2,TMEM31,PPP2R1A,MTX2,MTCH2,TOMM22,FKBP8,TOMM20,PXMP2,PSMC1,RAB3B,KRAS,BAG2,AKAP1,RAB9A,MAVS,P4HA2,EXD2 |
| 2.549e-08 | -17.48 | MRPS18C (mitochondrial ribosomal protein S18C) | protein interactions | 51023 | 190 | 89 | 19454 | 5460 |
MRPL11,AURKAIP1,METTL15,MRPS33,MEPCE,FASTKD5,RPL17,PPP1R12A,RPL3,MRPS18B,RPL23A,LANCL2,TMEM70,SNRNP70,NOL12,MOV10,GRSF1,E4F1,DBT,MRPS23,SURF6,SSBP1,MRPS9,SRP14,ALYREF,TRMT10B,PRR3,MRPS34,CHMP1A,HEXIM1,ZNF574,MTRES1,MYL12B,RBMS2,KLF12,UTP23,PRIM2,GFM1,SMG5,MRPS16,PPTC7,RPL26,TUFM,MRPS21,RPL13A,MRPS28,SRP54,RPL18,MRPS17,IMMP2L,HSPD1,UQCC2,HINT2,RPS24,MRPS11,SRSF7,MRPS26,MTRF1,RPL6,MRPS35,HNRNPA1,TRA2A,BTF3L4,TTC9C,CHMP2A,DNM2,SRSF1,PCBP4,GATD3,RPL27A,DUSP14,FGF17,NOP53,MRPS7,NGRN,EXD2,MRPS25,NOA1,MCAT,AUH,MYC,PMPCA,RPL35,RPL10,RPL19,TACO1,CCDC90B,RPS9,ZMAT2 |
| 2.603e-08 | -17.46 | PFDN2 (prefoldin subunit 2) | protein interactions | 5202 | 234 | 105 | 19454 | 5460 |
CCT8,TRIP4,RUVBL2,RPAP3,EWSR1,RUVBL1,PCGF3,KRAS,PFDN1,RAF1,TUBA1A,TUBB4B,MOB3C,UCKL1,POLR2C,POLR2D,PPP2CB,POLR2L,RPRD1A,IGBP1,TYMS,DYNC1I2,CDK17,HSP90AB1,CCT7,SLMAP,EGLN3,WWP2,PFDN5,DDRGK1,YWHAH,YWHAG,SKIC8,DCAF5,HSPB1,YWHAB,FBXW4,DUSP9,NUP50,STAU1,UFL1,SKP1,PRKAB1,PIH1D1,POLR2F,POLR3B,TUBB,SNRNP40,POLR2B,MYC,RNF40,DCAF4,YWHAZ,POLR1B,RIT1,PFDN6,HSP90AA1,PFDN4,MAP1B,HINT1,ABCE1,POC1B,DNAAF10,CDC40,DYNC1I1,PTGES3,RIGI,MEPCE,PDRG1,RRM1,RPAP2,ACTR1A,MAP1LC3B,DCAF12L2,ACTR2,POLR2G,EEF1AKMT3,POLR2I,FZR1,COPS5,TUBG1,SOD1,RPA3,BAP1,POLR1H,SUMO1,PIP5K1A,CD2AP,PRMT2,POLR1D,RPA2,RPRD1B,UBE2M,SMAP2,TUBA1B,CCNF,POLR3H,TRAF7,MAP3K3,USP14,PPP1CC,RC3H2,PKNOX1,UBE2H,DTL |
| 2.611e-08 | -17.46 | NCAPH (non-SMC condensin I complex subunit H) | protein interactions | 23397 | 296 | 127 | 19454 | 5460 |
STAU1,RP2,NUP50,HSPA8,RPS28,KLC2,NUFIP2,PLAA,PSMB3,H1-5,RPL27A,RPL10,RPL19,RPL35,RBBP4,PSMD6,MATR3,RPS9,RPL37A,PRMT5,EIF3K,DPEP1,RPS26,RPS5,RPS6KA4,LMNB1,MCM4,RBM15B,CAPG,RPL39,PSMD1,HNRNPC,MYC,RPS4X,RPL28,MCM6,RBBP7,RPS24,HECTD3,PABPC1,RPL31,RPS23,RPL18,MOB3C,MTA2,RPS11,RPS7,RPL29,CEP19,EGLN3,RPL7,RPLP1,RPLP2,RPL8,ARL11,RPL9,RPL23,CTNNB1,RPL6,PSMD3,PRPF19,MARS1,RPL4,SMC4,RPS15,RPA3,RPL27,BAP1,HECTD1,ACACA,RPLP0,RARS1,HEXIM1,CDK1,RPA2,CFTR,EEF1E1,RPS14,VIRMA,RPL22,ADRM1,RPL13A,RPS20,RPS12,GANAB,SRP54,SCAMP2,CCNF,RPS3,UBE2H,PDCD4,EIF3G,ST13,RPL7A,CEP85,RPL17,EIF3E,MEPCE,RPS13,KPNA2,HNRNPK,DHX9,RPL3,RPL23A,SRP72,ILF2,RPL15,ACTR1A,RPSA,TP53,YTHDF2,CDC5L,TMPO,PRNP,RPL35A,RPS16,RPL32,RPL12,H2AZ1,RPL10A,USP15,RPS2,PSMD7,RPL24,H2AC4,KARS1,CALR |
| 2.611e-08 | -17.46 | UCHL5 (ubiquitin C-terminal hydrolase L5) | protein interactions | 51377 | 296 | 127 | 19454 | 5460 |
UBE2M,HBB,LMNA,PAAF1,FTH1,UBLCP1,CCNA2,TPT1,PSMC4,HSPA5,GTF2I,KDM1A,PPIH,PRDX6,SQSTM1,BAP1,SMAD2,USP14,AR,CFL1,CTSD,PSMB2,IDE,ADRM1,TRIM54,PNP,TXN,CSNK2B,PSMC5,TRIM27,PSMA6,RAD23B,PSMC3,TMEM31,PSMB9,CAPZA1,RNF20,RBCK1,TRIM63,SEM1,PSMA5,HUWE1,PSME1,TFPT,USP15,MAP4,PSMD7,RPL24,CCDC92,PSMG2,ZFAND2B,CDC5L,PSMB1,SMAD3,ANXA7,FDFT1,KLC2,RNF7,PSMB7,PPP1CB,PRDX3,PSMB3,ACTL6A,DUSP14,UNC45A,FTL,CDSN,PSMC1,EEF1G,PSMA3,TXNL1,ARMT1,BRCA1,YWHAZ,PSMD14,PSMD1,PSMA4,USP5,PSMB6,TRIM46,PSMD6,ACTB,PSMD4,PRDX2,ELK3,SRXN1,LMBR1L,CYB5B,CHMP4C,KDELR1,EEF2,ACTN4,ISG15,RAF1,ANP32B,PSMD12,CBX7,RUVBL1,XPNPEP1,HNRNPF,PSMA2,PSMA1,ZBED1,UBE3A,RUVBL2,INO80C,HSPB1,PSMD10,HBA1,SKIC8,CSTA,CTNNB1,INO80E,PRDX1,PRPF19,PSMD3,GSTM3,EGLN3,OSBP,SNRPA1,CYB5A,XPO5,PSMB4,ANXA4,FBXO32,PSMB5,PSME2 |
| 2.647e-08 | -17.45 | TAGLN2 (transgelin 2) | protein interactions | 8407 | 201 | 93 | 19454 | 5460 |
ATP5F1B,ACTB,CLIC4,ENO2,DLST,MYC,RAB11A,CUL3,TOMM40,EIF1B,UCHL3,EMC1,STAU1,ACAA2,ELOVL1,PIH1D1,GSTO2,FKBP1A,FABP7,DUSP22,SUMO3,SUMO2,CACYBP,PPIA,FABP5,FOLR1,PHB1,IGBP1,GSTO1,AGR2,COTL1,YWHAB,PDIA3,CRIP1,WWP2,FKBP2,AHCYL1,CPLX1,PLS3,EZH2,CHMP4C,HSDL2,RAF1,PPIL3,SOX2,EEF2,TXN,SNX3,VIRMA,CCNF,ENO1,SNX12,PITPNB,TRIM24,MSN,CDC73,FKBP1B,UBE2H,CFL1,YKT6,PMP2,PIAS1,HSPA5,BAP1,RPA3,SOD1,PGK1,SQSTM1,PRDX6,GPX4,LMNA,RPA2,HEXIM1,ATG16L1,SPR,CFTR,CDK9,TES,MTAP,EIF5A2,NME2,MOV10,PGAM1,PSMA5,HSPE1,DUSP21,MDC1,SOS2,HSD17B10,HINT1,TAGLN3,KBTBD4,UBE2V1 |
| 2.668e-08 | -17.44 | ENY2 (ENY2 transcription and export complex 2 subunit) | protein interactions | 56943 | 158 | 77 | 19454 | 5460 |
MED23,RPLP0,SUPT7L,RPL27A,SUPT3H,RPL4,SGF29,UFL1,RPS28,RPL27,H1-10,TADA3,EIF3G,TADA1,UBE2H,RPS5,HNRNPC,RPL7A,MYC,TAF5L,RPL39,RPL13A,RPL35,APEX1,RPL22,RPL19,RPL10,EIF3K,RPS3,RPS12,RPS20,RPS9,RPL37A,SRP72,CSTPP1,RPL18,TAF10,RPS23,RPS11,YTHDF2,RPSA,RPS7,RPL15,RPL29,H2AX,JUN,KRAS,SEM1,RPL17,RPS13,RPL28,RPS4X,HNRNPA2B1,PABPC1,SNIP1,RPL31,RPS24,DHX9,RPL23A,RPL3,RPL24,RPL23,RPL10A,RPS2,TAF9,RPL6,EIF3D,RPL7,RPS16,RPL35A,TMPO,RPL32,RPL9,RPL8,RPLP2,CETN3,RPLP1 |
| 2.668e-08 | -17.44 | NGB (neuroglobin) | protein interactions | 58157 | 158 | 77 | 19454 | 5460 |
SNRPD1,SNRPD2,GNAO1,ZNF655,PTEN,ENO2,DLST,SLC25A31,ERH,GNAI2,RPL10,OTOS,PRDX2,ATP5F1B,RPL13A,RPL26,CFL1,ATP5F1A,AKT1,TRIM32,LDHB,CCNB1,NIF3L1,CKB,YWHAZ,PGK1,HADHA,TEX264,SNRPA,XRCC5,BANF1,HSPA5,HMGB1,DDIT4L,GSTP1,RPLP0,WTAP,RPA2,VAPB,HSP90B1,H2AC1,RPLP2,GNB3,SSBP1,ALYREF,HNRNPL,RPL7,YWHAG,HP,TBC1D5,PDIA3,HNRNPD,YWHAB,MAP4,HSPB1,EWSR1,SRSF8,PDIA6,DHX9,CCT8,RPS13,RPS4X,FLOT1,KRAS,TF,RUVBL1,TUBA1A,WBP11,MAP1LC3B,RPS7,RPL15,CCT5,RPSA,VAC14,KBTBD3,GNAI3,CBX3 |
| 2.730e-08 | -17.42 | MRM1 (mitochondrial rRNA methyltransferase 1) | protein interactions | 79922 | 348 | 145 | 19454 | 5460 |
LYAR,TMEM97,NDUFS8,CGGBP1,GATD3,MRPL18,DCAF11,MRPS26,MRPS35,STOML2,CLPX,MRPL9,NDUFV2,KGD4,ETFA,RETREG1,PREPL,MRPS11,VPS26B,HINT2,HECTD3,NDUFS6,AQP3,RIMOC1,EIF1AX,NDUFA12,ETFB,TRMT1L,RAF1,HSDL2,SERPINA3,FBXO22,ATP5F1B,MRPL23,ESR2,NDUFAF4,DLST,TACO1,MRPL13,TRMT11,MRPS25,WDR20,NOA1,PYCR1,PMPCA,CUL2,FMC1,AK3,OXCT1,NDUFS2,SELENOO,MRPS7,STX7,ATPAF2,NGRN,HADHA,ACAA2,ATP5PO,MRPS18A,NDUFA5,ZER1,AGTRAP,MRPL12,PRDX3,TIMM13,MRPL50,MRPL24,MRPS23,CNIH1,DBT,ATP5PD,MALSU1,COX4I1,MGME1,EIF4E2,MRPS9,SSBP1,COQ8A,SDHB,TMEM11,TMEM42,AQP2,TRMT5,GRSF1,LYPLAL1,ADIPOQ,DNAJC30,PDE12,MRPS33,ABHD10,MRPL22,ATP5PF,AGA,HSD17B10,EMC2,THG1L,MRPS18B,ERG28,NDUFS3,ACADSB,MRPL49,MRPL47,SELENOK,NDUFA2,MRPL11,ATP5PB,METTL15,SPRR1B,NRM,FNTB,PPIF,EEF1A1,GLRX5,GRPEL2,MGST3,GPX1,MRPS21,SUCLG2,VKORC1L1,ACAT1,MRPS28,SPOP,SYP,MRPS16,PYCR2,NDUFAF2,FTSJ1,MRPL41,MRPL40,NME4,POLDIP2,MRPL20,GRPEL1,IDH3A,DLAT,NXPE3,GFM1,TMEM243,MRPS34,SPRYD4,QRSL1,SIPA1L1,MRPL10,NDUFAB1,CDC42 |
| 2.795e-08 | -17.39 | IRAK1 (interleukin 1 receptor associated kinase 1) | protein interactions | 3654 | 302 | 129 | 19454 | 5460 |
IRAK4,HNRNPF,PELI1,ETFA,RPAP3,BAG2,CCT8,STK16,AQP3,JUN,EEF2,TOP3B,EGLN3,HSP90AB1,CCT7,TCP1,DUSP6,HAX1,HSPB1,IKBKB,AK2,TRAF6,FKBP4,RNF152,CPEB1,XPO1,IQSEC1,MAPK4,PFDN5,FAM174A,UNC45A,HSCB,RNF5,IL1B,HSPA8,TIFA,NUBP2,PIH1D1,VAPB,TIRAP,POLR2B,PPP5C,ABHD12,ATP5F1B,STAT1,GGT7,SARM1,PHF21A,FAM177A1,LMBR1L,NFKBIA,HSP90AA1,NTRK3,SERPINH1,CCT2,PELI3,FBXW11,BAG3,MCM4,MLF2,MYC,CUL3,NXPH3,FKBP8,PTGES3,TOLLIP,DNAAF10,CLPB,MYD88,SLC25A10,TLR4,MLLT11,TAB2,TMEM165,MGARP,CCDC47,CCT5,YTHDF2,ILVBL,TOMM70,CAV1,COQ8A,AIFM1,HRAS,AIP,EEF1AKMT3,SSX2IP,AKAP8L,DNAJC7,TUBG1,SLC2A1,BCL10,MZT2B,IRF4,ISYNA1,TICAM2,IL1RAP,IRF7,KDM1A,TLR2,SQSTM1,RPA3,CDK1,RPA2,LMNA,HPS6,RSAD2,SSR1,MRPL10,KLRD1,CNP,SUMO1,MAP3K3,OPTN,CCNF,STUB1,ATP1A1,ANAPC4,XPOT,UBE2H,IRAK1BP1,CALU,SDF2L1,TLR9,PPP1CC,ST13,AKT1,TRIM32,TNFAIP3 |
| 2.816e-08 | -17.39 | Hsp22 (Heat shock protein 22) | protein interactions | 3772576 | 145 | 72 | 19454 | 5460 |
DNAJC19,ATP5F1A,TUFM,NDUFB6,SLC25A1,NDUFB10,CHCHD3,ATP5F1B,ACAT1,CHCHD6,MRPL13,PTPMT1,RPS3,UQCRC2,VDAC2,CYB5R3,TFB1M,CYC1,SLC25A3,NDUFA5,ATP5PO,COX6C,TIMM23,STOM,COQ8B,TOMM22,UQCC3,CLU,HSPA5,PDHB,NDUFS2,PHB2,ATP5F1E,HADHA,ATP5MK,HAX1,POR,MPG,CLPX,KARS1,STOML2,SLC25A46,ATP5MG,TOMM70,ATP5PD,NDUFS8,SLC25A12,HSP90AB1,RPL35A,ATP6V1A,SSBP1,AIFM1,PHB1,COX4I1,SLC25A24,PDHA1,NDUFS3,PTRH2,HSDL2,ATP5PB,FKBP8,ETFA,VDAC1,ATP5F1D,PC,SLC25A5,NDUFB5,HSPD1,SFXN1,ARGLU1,SLC25A11,NDUFA4 |
| 2.820e-08 | -17.38 | RAC2 (Rac family small GTPase 2) | protein interactions | 5880 | 666 | 251 | 19454 | 5460 |
SRPRB,AKAP12,FKBP8,SLC6A8,SLC25A11,PALM2AKAP2,ABCE1,STX18,SLC16A1,BMPR2,TFRC,PREB,SNAP29,FCHO2,DNAJC1,VTI1B,ARL6IP5,SLC38A2,STX6,TMPO,LMAN1,ITGA6,STT3A,SLC39A10,ADD1,RAP1B,FLRT2,LANCL2,SLITRK5,SMAD4,NUS1,KPNA1,CD81,ARHGEF6,RAB9A,USE1,SSR1,SDCBP,CSNK1G3,LEMD3,GIT2,TFB1M,SPTBN1,CFTR,CDC42,ROCK1,NECTIN2,STX10,QSER1,TRAF7,ATP1B3,RAP2C,CISD1,ATP1A1,RAB2A,SLC25A1,SLC6A6,GORASP2,PRKACB,ARHGAP21,SLC20A2,NUP42,KRAS,RINT1,TMEM87A,CYP1B1,EFNB1,CDK5,MYO1B,STBD1,DIRAS1,VAMP7,SWAP70,RAB35,STX5,PTDSS1,RAB5C,WWP2,DDX50,DDRGK1,TBC1D5,CTNNB1,TENM3,YWHAG,PPFIBP1,OLR1,UFL1,EMC1,ABCC5,GNB4,ITGAV,AKAP1,PAK2,SDC2,TMEM184B,GOSR2,BET1,USP6NL,IL6ST,YIPF5,NCKAP1,ATP6AP2,FAM83B,RRAS2,H2AZ2,LAMTOR1,SPCS3,SLCO3A1,SLC38A1,SLC1A3,STX16,SLC30A5,PSMD1,CTNND1,GARRE1,DLG1,NSDHL,STX8,RAB1A,EMC2,SNAP23,KRIT1,ZDHHC8,CASK,DHRS7B,ALPL,CCDC47,SMAD1,SLC29A1,MTARC2,LBR,CAV1,EHBP1,HACD3,SRPRA,PTPN1,C2CD2,ESYT1,POR,SLC2A1,OSBPL8,LAMTOR2,RELL1,ATP1B1,DAG1,RAB23,HM13,PIK3R2,B2M,SLC7A1,CERS2,NF2,YKT6,TMEM209,CDC42EP4,MAVS,MTDH,SPCS2,SLC12A2,PICALM,STOM,GOLGA5,CTDSP1,JUP,ARHGAP1,SEC22B,PIP5K1A,SNRPN,RABL3,PDE8A,HACD2,UQCRC1,YES1,FERMT2,SH3BP4,CTNNA1,VAMP3,WDR45,SLC11A2,GANAB,NAPA,EPHA2,AGAP2,HMOX2,DEPDC1B,EMC8,AHCYL1,FLOT1,MAP3K11,BLOC1S2,SLC39A7,PCDH17,RPN1,STIM1,EZH2,VAMP2,CYB5B,ITGB5,STX12,EMC10,MACO1,MARCKSL1,FAF2,SPTAN1,TMEM237,PPIA,PHB1,WDR6,GJA1,PIK3R1,PRDX1,RAB32,WDR11,ATAD1,CYFIP2,STX7,EXD2,RTKN,CXCR4,ARMCX3,VAPB,NDUFA5,ELOVL1,TOR1AIP2,DAAM1,NOTCH2,FAM234A,ETF1,EHD1,ACTB,SPCS1,LRRC8A,PRDX2,USP5,CHCHD3,CYB5R3,FAM91A1,RMDN3,CLDN3,FZD6,MYO6,LMNB1,ELMO2,VMP1,SCFD1,SLC7A11,PKP4,RAB11A,VEZT,TOMM40,MRPL16 |
| 2.828e-08 | -17.38 | antioxidant activity | molecular function | GO:0016209 | 85 | 50 | 18094 | 5411 |
GPX4,MGST3,GSTO2,SOD1,TXNDC17,PRDX3,GSTK1,GPX6,GSTA1,SELENOW,MT3,MGST2,GPX3,TXNRD3,TXNRD1,HBM,HP,UBIAD1,HBE1,NQO1,TP53INP1,PRDX1,GSTP1,GPX7,PRDX2,PTGES,TXNRD2,ALOX5AP,SRXN1,CLIC2,PRDX6,SELENOS,SOD2,GPX1,HBB,GSTM2,GPX5,HBA1,GSTT1,IPCEF1,TXN,CYGB,SESN2,ALB,SOD3,SELENOT,GPX2,SELENOF,GSTO1,PRDX4 |
| 2.831e-08 | -17.38 | response to alcohol | biological process | GO:0097305 | 262 | 119 | 18204 | 5365 |
F7,MDM2,RGS19,GNRH1,ST6GAL1,GLRA1,MIR185,IGF1R,CREB1,SFRP1,TP53INP1,PTGER2,IL13,BGLAP,SOD2,CCL3,COMT,UGT1A1,ATP5F1A,GABBR1,HSPA8,DMAP1,GNG2,KLF9,CDK1,FOXP3,DAG1,KLF4,LEP,OPRM1,SETD7,PPARA,EPS8,ADCY3,PAX6,AKR1C2,ELK1,MSTN,CHRNB2,EFNA5,TUFM,CDO1,MLC1,TSPO,NQO1,BRCA1,SMAD2,MIR342,MYD88,JUP,TACR1,CLDN1,LIPA,OPRK1,CYP7A1,PTGER4,RPL15,MIR96,SLC6A3,POLB,ADIPOQ,TNF,PTGFR,DBH,AANAT,CTSK,BAK1,CRHBP,HNRNPD,CTNNB1,BIRC2,SLC23A2,KCNMB1,GNB1,MIR182,P2RY4,RGS2,AIFM1,AKT1,FBP1,CCR7,HDAC6,S100A8,FKRP,DRD3,FOS,RPL10A,BCL2L1,NPPC,LRP6,CDKN1A,GLRA2,SPHK2,USP46,PRKCE,ADCY2,PRKCB,OGG1,CRHR1,ACACA,TYMS,CCL21,RPL27,NEFL,CFTR,CYP1B1,CBL,CCR5,CTNNA1,G6PD,CD14,IL2,TGFBR2,CCL19,CLDN3,CNR1,CDK4,PSMD14,SOD1 |
| 2.843e-08 | -17.38 | positive regulation of cytokine production | biological process | GO:0001819 | 500 | 204 | 18204 | 5365 |
PQBP1,PRKCQ,IRF1,AFAP1L2,CCL1,OSM,PIK3R1,SETD4,PTGER4,TLR8,IFI16,EGR1,BMPR1A,GAPDH,TRIM15,TLR1,RAD21,LUM,TICAM1,IL15,KPNA2,IL7,ITK,IL23A,SEMA7A,B2M,SRC,SCAMP5,IL18,CD200,PDE4B,PIK3CG,ATF4,TLR4,DDIT3,LEP,CD40LG,TRIM27,TOMM70,CD58,PTPN11,IDO1,IFNG,IL17F,IL13,IL21,CLEC7A,TLR2,TRAF6,NLRP3,CEBPG,TICAM2,CYP1B1,MIR17,MIR657,CYRIB,TBK1,CCL19,TLR5,AIF1,IRF4,CCR2,SPHK2,TNFRSF14,CLEC9A,CHI3L1,CGAS,NLRP2,CD40,CLU,SYK,HILPDA,HMGB1,NLRP1,AGER,LURAP1,HRAS,PYCARD,BATF,IL1RAP,FCGR2B,CX3CL1,SMAD3,ROCK2,IL10,XCL1,CD2,SPTBN1,TNF,ADIPOQ,PHB1,TRIM6,LY96,SELENOK,RPS3,TRIM32,NMBR,TUSC2,FCGR2A,TRAF2,MIR145,MYD88,RGCC,BRCA1,IL4,TLR9,PLCB1,IFIH1,RUNX1,IL20RB,CD4,MIR21,NLRP9,PSEN1,CD81,CD46,MIR149,LILRA2,MIR324,MAVS,CLEC6A,RIGI,TYROBP,UCN,POLR3F,CD80,RAB1A,CD36,CD28,HSPD1,HTR2A,MIR132,DDT,BCL10,CD274,FOXP3,IL12A,ATP6AP2,LILRB1,SASH3,MIF,PNP,CD83,CCL3,PELI1,IFNGR1,FLOT1,CSF2,IL6ST,IRF3,HSP90AA1,TLR3,FGR,AKAP12,POLR3B,DEFB124,IL12B,DDX1,FCER1G,FOXP1,GPSM3,G3BP1,STOML2,CD86,HSPB1,IL6,RSAD2,FRMD8,AGPAT1,CD14,EIF2AK2,MIR206,KIT,PAEP,XBP1,SOD1,IL2,STAT1,TIRAP,JAK2,IRF7,TLR7,TRAF3IP3,CD34,OAS1,LTA,KPNA6,LACC1,IRF8,DHX9,IL1B,MIR182,PTPN22,TANK,UAP1,ISG15,TLR6,CCR7,MIR675,IL1A,MIR144,TMEM106A,LTB,HYAL2 |
| 2.846e-08 | -17.37 | AUP1 (AUP1 lipid droplet regulating VLDL assembly factor) | protein interactions | 550 | 226 | 102 | 19454 | 5460 |
AQP3,STIM1,RPN1,DNAJC25,FAF2,IMMP2L,RNF26,KRAS,TMT1A,RNF139,PEX3,RHOG,RAB5C,LAMP2,TMEM248,OS9,NUP35,RAMP3,EGLN3,RHOH,GJA1,PHB1,FBXO32,DUSP6,RAB35,OTULINL,RND2,SEC62,KCND3,PXMP2,ITGAV,STX7,RNF11,HSCB,AKAP1,RAB5A,EP300,OPRK1,ILK,HTRA2,LMNB1,RHOB,FBXW11,ATP1A3,CUL3,RAB11A,OPRM1,MYC,ESR2,APLNR,SEC61B,RMDN3,S1PR4,LMBR1L,TSPAN3,PCMTD2,SURF4,FNTB,UBL4A,KBTBD4,MDC1,FKBP8,SLC6A8,RAB3B,LRRN4CL,LPAR2,ESYT1,TUBG1,SLC2A1,LAMP3,FAM20C,SLC25A46,EDEM1,ADIPOR2,GRSF1,LMAN1,TMPO,DNAJC1,ARF6,RAC2,HSD17B11,UBE2G2,PTPN1,SSR1,GPR35,RPA2,LMNA,CFTR,ST7,CDC42,ITGA2,DERL1,RAB9A,SYVN1,VIPR1,RPA3,UBE2H,SEC63,RHOJ,NDN,SLC1A1,CCNF |
| 2.866e-08 | -17.37 | ARPC1B (actin related protein 2/3 complex subunit 1B) | protein interactions | 10095 | 204 | 94 | 19454 | 5460 |
RPS7,ACTN4,SERPINA3,B3GNT2,ANP32A,TPD52,RPL18,RPS23,RPS11,CTSA,EZH2,UBE3A,SLC25A5,RPL31,ANP32B,RPL28,TRIM37,KRAS,G3BP1,BTF3L4,ACTR3B,XPO1,POGK,IFI16,RPLP2,KRT8,CORO1C,SRSF1,EIF2S1,NDE1,DR1,STK26,NMRAL1,STAU1,SOX3,GON7,RPS29,DRAP1,BTF3,MYC,VMP1,H1-10,H2AZ2,BLVRA,CKB,EFHD2,ESR2,UBTD1,TOM1L1,ACTB,RPL35,DDX39A,TBK1,SERPINA1,NUPR1,CAPZA2,ARPC3,ACTR2,RPL23A,WASL,HDAC6,CALR,MOV10,MAP4,RPL24,TUBG1,SMAD4,PSMB1,RPL12,TMPO,ARL6IP5,CFTR,SUMO1,RPA2,ARPC2,RPL27,RPA3,HSPA5,FBXW7,RPS15,USP14,PRKACB,ARL6IP6,RPS17,DHPS,CALU,PDCD4,SPOP,CTTN,CREB1,SRPK2,SH3BGRL,DAPK1,LDHA |
| 2.872e-08 | -17.37 | CNBP (CCHC-type zinc finger nucleic acid binding protein) | protein interactions | 7555 | 268 | 117 | 19454 | 5460 |
SYNCRIP,RPL12,DFFA,RPL32,RPS16,RPL35A,PRNP,DKC1,SURF6,KLF9,KARS1,DPP4,SMCHD1,NOL12,RPL10A,RAB1A,NKRF,PSME1,RPL23A,KLF10,SEPTIN7,RPL3,DHX9,PAK1IP1,CSE1L,RPS13,MEPCE,RIGI,RPL17,FBP1,TP53,FCF1,RPL15,LLPH,RBM34,FURIN,CCNF,PTEN,RPL13A,FERMT2,HOMER1,RSL24D1,DYRK1A,CARS1,RPF2,RPL7A,RPL26,AR,ZSCAN25,NRP1,IGF2BP1,UBE2H,RPL27,BAP1,RPA3,NLE1,RNF113A,RPL4,BRIX1,MARS1,ING5,CDC42,CDK7,IDH2,MET,RPLP0,HEXIM1,HNRNPH3,RPL26L1,RPL8,RPLP2,RPLP1,HP1BP3,MEAF6,RPL7,RPL6,RPL31,FKTN,TRIM37,TOP3B,RAF1,MAK16,MSX2,PLS3,EZH2,NGB,BZW2,RPL18,ZNF22,RAN,RPL37A,SNRPD2,RPS9,RPF1,RPL7L1,ERH,ESR2,MYC,RAB11A,HNRNPC,CUL3,HNRNPAB,BTF3,FYTTD1,FTSJ3,H1-1,NSA2,DNAJC3,CCDC86,RAB5A,STAU1,NOP53,KCND3,H1-5,BET1,KLF3,APOBEC3C |
| 2.883e-08 | -17.36 | CCT5 (chaperonin containing TCP1 subunit 5) | protein interactions | 22948 | 484 | 191 | 19454 | 5460 |
CDC5L,MBD5,TMPO,FZR1,SPPL3,B9D1,CSNK2A1,TUBG1,POC1B,MAP1B,CAPZA1,STRADB,MEPCE,DYNC1I1,KDM4B,H2AX,ACTR1A,RPAP2,TP53,RNF8,MOB4,PSMA6,DYRK1A,CDC20,BUB3,PTPN11,AKT1,MAT2A,SLC25A1,UBE2H,DTL,ZBTB38,TRIM23,RC3H2,HCFC2,NLE1,BAP1,HDAC3,CFTR,GABRA1,UBE2M,HEXIM1,SSR1,SAMM50,WRAP53,TRIM68,RPA2,WDR82,CCT7,HSP90AB1,PNPLA8,DYNC1I2,SUMO2,TCP1,DDRGK1,XPO1,MAPK4,IFI16,AGR2,DCAF5,ACTR1B,SCPEP1,CDK5,RPAP3,CCT8,PABPC1,CTTNBP2,CBLL1,HNRNPDL,KRAS,TUBA1A,SOX2,SLC4A8,TUBB4B,PLS3,MCPH1,ESR2,SNRNP40,FBXO22,PSMA4,KLHDC8A,APOBEC3B,MYC,COP1,PSMD14,CCT2,DDX5,HDAC5,HSPA8,DDX39B,SLU7,STAU1,SRSF2,UFL1,FBXO42,PIH1D1,PACRG,EIF4B,PPT1,PSMB1,ACTA2,EEF1AKMT3,PTPN1,CDK9,KCTD15,SUV39H1,HDAC6,EMC4,FNDC11,FGR,CRBN,HAPSTR1,RIGI,FBXO25,HSPE1,DNAAF10,HUWE1,PPP4C,ACTR2,ZBTB18,GANAB,GSK3A,METAP2,TUBA1B,SMAP2,STUB1,CCNF,PDCD5,VIRMA,ARMC6,NDN,USP14,CIAO1,SEC13,CDC73,STK24,SQSTM1,SIRT7,PRPF4,RPA3,AATF,IRF7,CCND1,ATG16L1,WDR83,PDCL,METTL14,CDK1,IGBP1,PPP2CB,TRAF3IP3,PHB1,FOLR1,CETN2,DHX15,EGLN3,DCAF11,PPM1B,SKIC8,ZC3H7A,AKT2,AHCYL1,PCGF6,RBBP7,PCGF3,RAF1,POLR2C,NME1,NGB,EZH2,GNB1,ACTB,MTM1,PRDX2,CUL2,CUL3,KLHDC8B,ILK,DCAF4,BRCA1,PSMA3,TERT,TXNL1,FBXW4,THOC3,PPP2R2C,DET1,ALKBH3,WDR77,TBC1D17,PSMB7 |
| 2.887e-08 | -17.36 | NDUFA4 (NDUFA4 mitochondrial complex associated) | protein interactions | 4697 | 305 | 130 | 19454 | 5460 |
COIL,ADRB2,ATAD1,TMEM177,UFL1,HSCB,NDUFS2,HADHA,ATP5F1E,ATP5MK,PRKD3,SLC25A3,NDUFA5,ATP5PO,TIMM29,NDUFAF3,MTX2,MAD2L2,CHCHD3,TIMM21,TAMM41,CYB5R3,VDAC2,ILK,FIS1,NTRK3,ATP1A3,COX11,TOMM40,CUL3,NDUFB7,TNF,GUK1,CHCHD2,COX8A,NDUFA4,BCKDK,UQCC2,NDUFB5,CYB5B,NDUFA12,PDHA1,NDUFS6,RAF1,TOP3B,RMND1,EGLN3,NDUFS8,AGK,ST3GAL4,NDUFB8,PDCD10,POU5F1,AGR2,DDRGK1,NDUFV2,STOML2,WWP2,ATG9A,POLDIP2,FBXW7,PDHB,MAIP1,RPA3,CYC1,ACACA,MET,FGFR1,GHITM,SAMM50,HSP90B1,COX6C,RPA2,CDC42,MPV17,TIMMDC1,VIRMA,UQCRQ,ROMO1,SLC25A4,CPT2,UQCRC2,CCNF,DNAJC19,UBE2H,NRP1,CISD1,NDUFAF2,SLC25A1,NDUFB10,UST,CHDH,IGF1R,CLPB,ABCE1,SLC16A1,SFXN1,SLC25A11,ATP5PF,SLC25A10,SLC25A24,FURIN,NDUFS3,TMEM205,FAM162A,NDUFA2,MTCH2,ATP5PB,UBL4A,TMEM126A,SNAP29,B4GALT6,SLC25A12,CDK9,FAM118B,EPHB6,RAB39B,ATP5PD,FZR1,COX20,NDUFB4,COX4I1,SDHB,ACSL4,COQ8A,STYK1,TMEM70,NME2,COX5A,CALR |
| 2.902e-08 | -17.36 | response to hypoxia | biological process | GO:0001666 | 292 | 130 | 18204 | 5365 |
CDKN1B,ALKBH5,RGCC,SUV39H1,PPARG,SCFD1,CAPN2,FZD4,PGK1,AQP3,MIR146A,CCNA2,NFE2L2,EPO,SLC6A4,CAV1,NR4A2,RAD21,MECP2,EDNRA,EGR1,VEGFA,MIR210,PMAIP1,CHRNA7,CHRNB2,MSTN,CAV3,BNIP3L,COMT,FAM162A,KCNJ11,MGARP,SOD3,CIAO3,ADORA1,SRC,PSEN2,CLCA1,PHB2,VEGFC,LEP,PPARA,HMOX2,MIR140,TM9SF4,ATF4,MDM2,MIR223,F7,SLC2A8,MIR106B,TP53,MMP14,ERCC3,SFRP1,MIR126,MYC,CYGB,MIEF1,CRYAB,SOD2,ACAA2,MIR34A,MIR20A,TERC,CPEB1,MIR214,MIR17,CD38,NDP,HP1BP3,CBL,TLR2,ERO1A,BECN1,SLC29A1,DPP4,CLDN3,CYP1A1,FOS,NPPC,NGB,GAD2,PML,HSP90B1,EGLN2,ADO,PRKCE,TERT,KCNJ8,FOSL2,LTA,MIR448,BAD,STUB1,HILPDA,LMNA,NDNF,KCNMA1,TGFB3,KCND2,AIFM1,CXCL12,WDR83,NOP53,DDIT4,CXCR4,NKX3-1,ITGA2,SMAD4,AGER,CREBBP,FUNDC1,SLC2A1,TNF,ADIPOQ,UCP2,DIO3,STC1,EP300,IL1A,TGFB2,SMAD3,AGTRAP,BIRC2,TFRC,EGLN3,MT3,KCNMB1 |
| 2.956e-08 | -17.34 | S Phase | REACTOME pathways | R-HSA-69242 | 130 | 71 | 10285 | 3229 |
CCND1,PSME1,GINS4,CDK7,SKP1,PSMD10,PSMD7,MNAT1,RAD21,POLE3,PSMD14,RB1,UBB,UBA52,PSMB1,POLD4,PSMB7,RFC2,PSMD3,ORC5,PSMC4,CDK4,CDKN1B,PSMA3,PSMB5,PSMA5,CCNH,PSMB10,PSMC5,PSMB11,PSMA4,MCM4,PSMB3,RPA2,POLD2,PSMB6,MCM6,PSMA2,PSMB4,PSMD6,RFC5,RPA3,PSME2,ORC6,RFC3,MAX,SEM1,PSMB9,FZR1,PSMA1,PCNA,PSMC3,RFC4,CKS1B,CCNA2,PSMD4,MCM3,PRIM2,RPS27A,CDKN1A,MCM8,GINS3,PSMC1,POLA2,PSMD12,MYC,POLE4,FEN1,PSMA6,PSMD1,PSMB2 |
| 3.000e-08 | -17.32 | POP1 (POP1 homolog, ribonuclease P/MRP subunit) | protein interactions | 10940 | 271 | 118 | 19454 | 5460 |
SNRNP70,H2AC4,COPS5,CSNK2A1,PPIL4,ELOC,MOV10,RBM42,ZBTB2,SURF6,FZR1,CAND1,RPS16,TOP1,CGAS,KRR1,SRP72,TAF2,DDX42,RBM34,POP5,TP53,RPSA,EGR1,MEPCE,RPL17,NEDD8,H3C1,RPL23A,RPL3,SNIP1,ZBTB38,UBE2H,MECP2,RC3H2,RPL26,NONO,DNAJC8,RPL7A,PPP1R10,RPP25,VIRMA,SRPK2,ZNF622,RPL13A,RPP25L,PRKRA,FGFBP1,PTEN,PSPC1,CCNF,POP7,CTTN,RPLP0,HEXIM1,TOX4,RPA2,GRM2,FGF13,DGCR8,NPM3,RPL4,RNF113A,INPPL1,RPA3,PPM1G,SIRT7,CBL,DDX1,DRG1,DICER1,AGR2,DDRGK1,IFI16,RPS10,EIF2S1,RPL7,RPL8,SRSF1,FBXO32,RBPJ,MOB3C,SART3,CHMP4C,SOX2,H1-3,RAF1,E2F4,GTF3C3,KRAS,G3BP1,FAM76B,TRIP4,RPL31,H1-1,RCL1,RIT1,ATG3,MLF2,MYC,PYCARD,CUL3,ESR2,RPL19,RPL10,SNRNP40,RPL7L1,SURF2,NUFIP2,MFAP1,PIH1D1,RPP21,SYK,RPP14,G3BP2,ZNF692,UFL1,EP300 |
| 3.008e-08 | -17.32 | RAB8A (RAB8A, member RAS oncogene family) | protein interactions | 4218 | 161 | 78 | 19454 | 5460 |
FURIN,PDE6D,TFRC,GDI2,MAP1LC3B,SOX2,UBL4A,RAF1,RAP1A,CENPM,RAB8B,SRPRB,RAB3B,MKLN1,RAB13,HSD17B10,RAB1A,PQBP1,MAEA,ARMC8,RHOG,STK4,COX5A,RAB5C,CACYBP,MDM2,WIF1,RAB11B,RAB1B,OCRL,RHOH,RAP1B,RAC2,SDHB,RAB31,CD274,ANXA4,SSMEM1,TBC1D17,HEXIM1,NDUFA5,RPA2,FGFR1,STOM,SAMM50,HSP90B1,CDC42,RND2,EHD1,FBXL19,EHD3,RANBP10,RNF41,STAU1,FLCN,RMND5B,SQSTM1,AKAP1,RAB5A,RHOU,RPA3,GID8,FOS,EXOC8,NRP1,CDC73,YPEL5,RHOB,EXOC5,C9orf72,RAB11A,CHCHD3,CEP97,RABIF,RHOJ,SLC1A1,VAMP3,OPTN |
| 3.024e-08 | -17.31 | SURF6 (surfeit 6) | protein interactions | 6838 | 407 | 165 | 19454 | 5460 |
RPLP1,RPLP2,SRSF1,RPL8,ARL11,ZNF593,RPL7,KCTD10,LYAR,ISG20L2,RPS10,MAP3K14,NT5C2,RPL6,MRPS35,IFI16,DDX50,LHX2,MRPS26,DEGS1,DDX23,ZCCHC9,RPS24,MRPS11,COX8A,RPL31,RFC3,RPL28,VDAC1,HMGN4,KRAS,MAK16,H1-3,TRAF2,JUN,TOP3B,RPL18,PDHA1,EZH2,GLE1,RPL37A,ZNF189,PARP2,ZNF22,ESR2,RPL10,RPL19,APEX1,RPL7L1,RPF1,RPL35,FBXO22,SNRNP40,ZNF668,RAB11A,MYC,DNAJB6,H1-1,NSA2,RPS5,DCAF4,MRPS25,ZCRB1,FTSJ3,NOA1,MYO6,EP300,CCDC86,ATP5IF1,SF3B1,SPECC1L,IMPACT,MRPS7,NOP53,STAU1,BET1,SYK,H1-5,VAPB,APOBEC3C,PWP2,ARL4D,ARL10,KRR1,AIFM1,MRPS9,SRP14,ZBTB2,DBT,CGAS,RPS16,E4F1,CSNK2A1,SPATS2L,DPP4,GRSF1,MOV10,CMSS1,BRD3,RPL10A,NOL12,RPS2,CHCHD1,RPL3,HAPSTR1,RPL23A,NKRF,SNIP1,RPL17,RIGI,ARF4,MRPS18C,RPS13,IMP4,NOC4L,CTNNBL1,PAK1IP1,FCF1,RPL15,RPSA,SRP72,CASK,RBM34,LLPH,FGFBP1,PRKRA,ZNF330,EIF2AK2,CCNF,OPTN,SRPK2,RPL22,RSL24D1,RPL13A,RACGAP1,ZSCAN25,RPS17,RPL7A,RPF2,HSPA14,UBE2H,TRIM23,MRPS16,RNF113A,MNS1,NLE1,SIRT7,RPA3,AATF,UTP23,CDC42EP4,MRPL41,RPL4,WDR3,NPM3,DGCR8,RPS15,FGF13,CDK7,RBFOX2,ZNF770,RPL26L1,RPLP0,ZNF574,RPA2 |
| 3.094e-08 | -17.29 | NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8) | protein interactions | 4728 | 243 | 108 | 19454 | 5460 |
GFM1,PDHB,SLC25A51,CRYZ,ABCC2,TIMMDC1,MPV17,CDC42,UQCRC1,HSP90B1,SAMM50,RPLP0,CYC1,MTRES1,UQCRC2,UQCRQ,VIRMA,NDUFB10,TUFM,HMOX2,DNAJC19,UBE2H,RAB1A,SFXN1,CLPB,EMC2,DNAJC30,PSEN1,FASTKD5,MTCH2,MRPL11,AURKAIP1,APOO,MAP1LC3B,METTL15,NDUFS3,GFM2,SSBP1,AIFM1,SDHB,COX4I1,NDUFA1,MYL12A,GRSF1,MTMR12,EMC4,POR,TMEM70,CHCHD1,NGRN,EXD2,HADHA,HSCB,NDUFS2,PHB2,TOMM22,OTULINL,NDUFAF3,TIMM29,ARMCX3,NDUFA5,SLC25A3,VDAC2,TACO1,LMBR1L,MTG1,CCDC90B,ATP5F1B,ACTB,MAD2L2,PARL,ESR2,NDUFAF4,AUH,MTG2,NDUFB7,CUL3,PMPCA,TOMM40,PCCB,HTRA2,HSPD1,NDUFB5,NDUFA4,HINT2,EMC8,VDAC1,IMMP2L,RAF1,EEF2,NDUFS6,PDHA1,NDUFA12,PHB1,CORO1C,ATP6V1A,GATD3,RAB1B,UQCRH,EGLN3,COX14,RMND1,MTRF1,NDUFV2,DDRGK1,RHOG,MRPS26,NDUFB8 |
| 3.176e-08 | -17.27 | AQR (aquarius intron-binding spliceosomal factor) | protein interactions | 9716 | 188 | 88 | 19454 | 5460 |
RPA3,SIRT7,MIR205,MIRLET7I,RBM22,MIR7-3,MIR107,MIR29A,MIR34B,WDR83,SF3A1,SNRPN,RPA2,LSM2,MIR7-1,EIF4A3,SRC,VIRMA,MIR145,ELAVL2,PDCD4,UBE2H,SNIP1,PQBP1,ZC3H11A,H3C1,TSSC4,SNRPG,MIR200C,CD2BP2,MAP1LC3B,CDK8,ILF2,MIR106B,EEF1AKMT3,MIR25,FZR1,NKAP,MIRLET7G,NCBP2,MIR429,CDC5L,KIAA1143,SNRNP70,MIR34A,ATP6V1D,SNRPA,DDX39B,NKAPD1,STAU1,MIR106A,PABPC5,WDR77,RALYL,SNRNP40,RBBP4,MIRLET7D,SNRPB2,ESR2,MYC,HNRNPC,SNRPB,LMNB1,RIT1,MIR206,SRSF7,RTCB,KRAS,NUP42,SSRP1,SUPT5H,MIR222,LGR4,EZH2,SNRPE,MIR7-2,MIR214,SNRPD3,SNRPA1,PRPF19,ZCCHC10,YWHAG,HNRNPA1,YWHAH,MIR31,MIR221,MIR1-1,MAGOH |
| 3.203e-08 | -17.26 | proteasome complex | cellular component | GO:0000502 | 62 | 39 | 19108 | 5553 |
PSMC1,PSME2,PSMB10,PSMD14,TXNL1,PSMA5,PSMB5,HSPB1,ZFAND2B,PSMB7,PSME1,PSMD6,PSMA3,PSMA1,PSMC3,PSMC4,PSMD7,PSMA4,PSMA6,PSMD12,PSMB4,PSMB6,PAAF1,PSMD10,PSMD4,USP14,ZFAND2A,PSMC5,PSMD1,PSMB3,ADRM1,RAD23B,PSMB1,PSMB9,PSMB11,PSMD3,PSMB2,UBE3A,PSMA2 |
| 3.213e-08 | -17.25 | cytokine-mediated signaling pathway | biological process | GO:0019221 | 384 | 163 | 18204 | 5365 |
IL2RB,IFNG,FCER1G,TP53,IL12B,CXCL9,RRAGA,CXCL8,CCL5,IL17F,IFNA10,IFNAR1,MIR34A,GPR17,LEPR,ADIPOR2,TRAF3IP2,CCL17,AZI2,TXNDC17,IL6,SRC,IL12A,GHR,LILRA3,MX1,LILRB1,CNTFR,RPS6KA4,PRL,ACKR3,CCL3,IL18,IFNGR1,LEP,CCL11,IL6ST,HAX1,OXSR1,CSF2,PTPN11,CCL8,IRF3,IL34,MAVS,IKBKB,EGR1,MKKS,CAV1,IFNB1,IFI27,IL15,SIN3A,EPO,GPR35,IL7,IL3,LILRA1,MYD88,IRF1,OSM,CCL1,IL4,JAK1,IRAK4,IFIH1,PIK3R1,TNFRSF1B,IFNK,PLCB1,SOCS5,IL20RB,IFNA2,CD4,LILRB4,CXCL3,MIR146A,LILRA2,CXCL13,FZD4,RAF1,IL1A,CX3CL1,XCL1,CCR3,PLP2,NFKBIA,ZC3H15,TNF,MT3,CCL24,CXCL11,EDA2R,IL2RG,BIRC2,JAGN1,TRAF1,SLC1A1,GH1,CX3CR1,TRAF2,CXCL12,AKT1,IL1B,CXCR1,CCL23,SYK,CXCR6,CCR4,PYCARD,TNFSF18,CXCL1,CCL20,SMAD4,ADIPOR1,TANK,IL1RAP,IFNA13,CCR6,CCR7,CXCR4,STAT6,STAT1,ACTN4,TMSB4X,TNFRSF14,IL2RA,CXCL10,IL5,CCL2,IRF7,HCLS1,JAK2,BAD,UGCG,GPR75,KRT8,CCL4L1,GREM2,OAS1,CCL18,ILK,IL15RA,WBP1L,CCR1,CCL25,TRAF6,CCR5,FAS,CBL,STAT2,KIT,CXCR3,IL1R2,TOLLIP,CCL21,CSNK2B,TBK1,STAT5A,IL2,CCR2,TIFA,CCL19 |
| 3.251e-08 | -17.24 | CCT2 (chaperonin containing TCP1 subunit 2) | protein interactions | 10576 | 624 | 237 | 19454 | 5460 |
CDK7,GABARAPL2,ATG16L1,WDR5B,WDR83,CCND1,PDCL,METTL14,HSP90B1,FLCN,SQSTM1,DVL2,SOD1,RPA3,SIRT7,PRPF4,GABARAP,IRF7,GTF2I,FBXW7,USP14,PPP1CC,TAF5L,CIAO1,CDC73,NAPA,STK24,TXNIP,ZBTB18,PPM1M,GANAB,PTEN,CCNF,METAP2,TUBA1B,SMAP2,PDCD5,VIRMA,ABHD17A,NDN,YES1,ARMC6,MAP1LC3B,CCT5,TRIM6,PPP4C,KLHL26,MMACHC,ACTR2,HAPSTR1,HSD17B10,RAB1A,GLUL,KATNAL1,RIGI,HUWE1,DNAAF10,HSPE1,HDAC6,SUV39H1,FNDC11,FGR,EEF1AKMT3,CDK9,PRNP,DET1,ALKBH3,ACTL6A,WDR77,VAV2,TXNL1,PSMA3,THOC3,FBXW4,FBXL4,ARL6,PPP2R2C,NSFL1C,RNF40,KLHDC8B,CUL3,HSP90AA1,RIT1,ILK,BRCA1,DCAF4,RAN,GPR37,GNB1,FCHSD2,PRDX2,ACTB,TUBB,MAPK10,GABARAPL1,ERLIN2,WDR37,B3GNT2,RAF1,POLR2C,GNB1L,CYB5B,EZH2,NME1,ZC3H7A,HECTD3,PCGF6,RAD21,RBBP7,PCGF3,DCAF11,AHSA1,SKIC8,IGBP1,MAP1LC3A,GJA1,FOLR1,ARL11,PPP2CB,PHB1,EGLN3,CETN2,GABRA1,CFTR,UBE2M,HEXIM1,TRIM68,WRAP53,RPA2,SAMM50,SSR1,BAP1,HCFC2,NLE1,HDAC3,AKT1,MAT2A,SLC25A1,DTL,ATP1A1,UBE2H,RAP2C,SPOP,RC3H2,MOB4,RPS3,SMURF1,CDC20,BUB3,KCTD9,DHRS13,ACTR1A,ZMYM4,KBTBD4,TP53,TFCP2,POC1B,MAP1B,METTL18,MEPCE,CAPZA1,STRADB,DYNC1I1,CDC40,KDM4B,HNRNPK,TOLLIP,B9D1,CSNK2A1,COPS5,TUBG1,SHC1,H2AC4,NPSR1,TMPO,CDC5L,MIOS,FZR1,FBXO42,EIF4B,PIH1D1,CNDP2,PACRG,PPT1,HDAC5,P4HA2,HSPA8,DDX5,THBS3,AKAP1,RCCD1,UFL1,STAU1,APOBEC3B,MYC,KLHDC8A,COP1,PLA2G15,PELI3,PSMD14,ANAPC2,DLST,CBX5,ESR2,SNRNP40,TUBA1A,ISG15,SOX2,EEF2,RHOBTB1,TUBB4B,PDHA1,HDAC11,CDK5,ACTR1B,CTTNBP2,CCT8,PFDN1,KRAS,YWHAG,DDRGK1,ACTR3B,CTNNB1,DCAF4L2,PFDN5,WWP2,DCAF5,AGR2,EED,WDR82,DUSP6,TRMT61A,CCT7,HSP90AB1,DYNC1I2,TCP1,SUMO2 |
| 3.253e-08 | -17.24 | SF3B4 (splicing factor 3b subunit 4) | protein interactions | 10262 | 317 | 134 | 19454 | 5460 |
HNRNPA2B1,HSPD1,EWSR1,MIR155,HNRNPF,KRAS,TFG,MIR222,H1-3,ISG15,SMNDC1,SNRPE,SF3B5,PHB1,SRSF1,MIR141,MIR9-1,SNRPD3,SNRPA1,PAIP1,DHX15,WWP2,ZCCHC10,PRPF19,MIR29C,HNRNPA1,CRTAP,MIR31,HNRNPD,MIR221,MIR1-1,BMPR1A,SNRPA,RAMAC,SF3B1,HSPA8,STAU1,YTHDF1,UFL1,SRSF2,TRA2B,MIR106A,WDR77,TIMM13,ACAA2,FKBP1A,TACO1,SNRPD2,SNRPD1,ESR2,SNRPB2,MIRLET7D,CUL3,HNRNPC,MYC,BAG3,RBM15B,SNRPB,TTC33,PSMD14,RIT1,MIR363,MIR200A,ZC3H11A,HAPSTR1,SRPRB,CTNNBL1,MIR16-2,SNRPG,MEPCE,MIRLET7C,EEF1A1,MIR200C,CD2BP2,MIR17,DDX42,NUPR1,PPP4C,ILF2,ALYREF,SSBP1,MIR106B,MIR25,MIRLET7G,CAND1,FZR1,CWC15,CDC5L,MIR429,RBM17,API5,PPIL4,COPS5,SNRNP70,MIR34A,RPS2,MIR205,GLIPR1,MIR10B,BAP1,DDX46,MIR34C,MIRLET7I,MIR7-3,NF2,MIR29A,MIR107,SNRPN,ACBD6,WDR83,MIR34B,SF3A1,RBFOX2,STOM,GRM2,METTL14,P3H1,MIR7-1,MIR21,TFIP11,CTTN,OPTN,CCNF,SF3B6,MIR16-1,PSPC1,UBE2I,COPE,VIRMA,RPP25,PPP1R10,DNAJC8,MIR145,UBE2H |
| 3.258e-08 | -17.24 | regulation of canonical NF-kappaB signal transduction | biological process | GO:0043122 | 287 | 128 | 18204 | 5365 |
FLOT1,TRIM21,PELI1,FASLG,SQSTM1,TLR4,IRF3,NKIRAS1,BCL10,ANGPT1,SNIP1,TRIM34,PRL,MIR15A,ZFAND6,HSPB1,TRAF3IP2,AZI2,CLEC7A,MAP3K3,TRIM68,TLR3,DDX1,TAB2,TNFSF10,LPAR1,ATP2C1,CCDC22,CD4,LILRB4,MIR146A,UFL1,CPNE1,MYD88,IRAK4,TLR9,TRIM52,OPTN,PIM2,MIR195,VEGFA,CD36,MAVS,IKBKB,CLEC6A,RBCK1,GAPDH,EDNRA,CARD19,TMEM101,PPM1B,SLC20A1,CAV1,S100B,TICAM1,PYCARD,MTDH,LURAP1,TANK,TRIM5,NFKBIL1,CCR7,ZDHHC17,TLR6,TMED4,WDR83,CD40,IL1B,ZMYND11,UBE2V1,NFKBIB,CXXC5,TMEM106A,TRIM62,TLE1,TRIM6,EDA2R,TRIM8,BIRC2,TFRC,OTUD7B,LTB,TRAF1,TRIM32,TNFAIP3,CX3CR1,TRAF2,GSTP1,IL1A,CX3CL1,MUL1,NFKBIA,ADIPOQ,TNF,MIR497,LITAF,TBK1,UBE2N,RHOH,TIFA,CCL19,LTBR,TRAF6,NDFIP1,TICAM2,TRIM22,GJA1,CCL21,GPR89A,ILK,NKIRAS2,FBXW11,PRKCB,MIR16-1,PRKCE,IRAK1BP1,NUP62,STAT1,JMJD8,BST2,SPHK2,TMSB4X,TIRAP,DHX15,TFG,PPP5C,FKBP1A,NLRP6 |
| 3.305e-08 | -17.23 | TUBGCP3 (tubulin gamma complex component 3) | protein interactions | 10426 | 221 | 100 | 19454 | 5460 |
BAG2,EFNB1,RPL31,HSPD1,RPS4X,SEMA4C,PSMA1,KRAS,RPS7,LPAR6,TUBA1A,RAF1,SEC61G,VPS33A,TUBB4B,S100A8,MAGED2,FBXO32,RPL8,FABP5,HSP90AB1,LRWD1,UQCRH,EGLN3,DYNC1I2,CDK17,RPS10,HNRNPA1,XPO1,PRPF19,RPL23,HAX1,POU5F1,DCAF11,PDCD1,DDX5,HSPA8,MRPS7,FTL,SKP1,SAP18,NEK7,FAM234A,KLC2,RPS9,ANAPC2,RPL37A,S1PR4,SCN2B,CD79B,PRRC2A,RPL10,APLNR,RBBP4,TUBB,ACTB,CUL3,OPRM1,MYC,RIT1,DNAJB6,MRPS25,FBXW11,MRPS18B,RPL23A,AKAP12,ESS2,CD2BP2,SIGLECL1,EIF4E2,ACSL4,MRPS23,CDC5L,MZT2B,MOV10,RPS2,DNAJC7,RPL24,MUL1,TUBG1,VIPR1,RPA3,SNAPC1,HSPA5,RPS15,LIAS,ATG16L1,RPS14,HECTD1,RPA2,MRPS28,CCNF,RPS3,TXNDC12,LYPD6,MRPS21,RPS17,RPL26,UBE2H,IGF2BP1 |
| 3.315e-08 | -17.22 | USP9X (ubiquitin specific peptidase 9 X-linked) | protein interactions | 8239 | 381 | 156 | 19454 | 5460 |
BIRC2,HSPA8,HDAC5,CRY1,EP300,ARRDC3,NUBP2,AKAP1,HADHA,UCHL3,STAU1,G3BP2,ALKBH3,PGRMC1,RND2,ADNP,EIF4B,SRXN1,LMBR1L,SEC61B,MATR3,FBXO22,UBE2V2,ESR2,ALDH1L1,CUL3,PSMA4,GRB10,MAP3K21,CASP4,BAG3,SNRPB,BRCA1,LMNB1,RHOB,NLRP3,RIT1,ZYX,BCL9,FAM168A,UFM1,GNL1,RUVBL1,RPS27A,GTF3C3,SRSF4,COPS4,PAK6,AHCYL1,CSNK1E,ZNF263,SOX2,NFKBIL1,TUBB4B,KLHL12,RHOBTB1,MOB3C,PSMB4,IGBP1,GJA1,COPS2,KRT8,TCP1,SUMO2,ATXN10,RHOH,PEG10,EGLN3,HMGA1,SAV1,WWP2,XPO1,CTNNB1,NT5C2,DDRGK1,UBE2D1,RHOG,PPM1B,POU5F1,PEX3,RPA3,SOD1,DVL2,RHOU,BAP1,SIRT7,KDM1A,FBXW7,PIK3R2,UBA52,TPT1,GABRA1,CDC42,CFTR,RPA2,WWP1,HEXIM1,HECTD1,KLF4,CCNF,PHAX,HEXIM2,PTEN,SGTA,MACROH2A1,RHOJ,UBE2L3,SMURF1,VIRMA,RSPH1,PIP4K2C,GEMIN8,TXNIP,SMAD2,ZBTB38,NRP1,UBE2H,ALKBH5,MAP1B,CPNE2,PTGES,IGF1R,RNF115,CAMKV,HUWE1,SMN1,TP53,MAP2K3,SMAD1,UBE2B,NFE2L2,BIRC5,SMAD3,CD274,ALDH1A3,RCHY1,MCL1,RAC2,LDLR,SEC23A,TES,CAND1,ARL6IP5,FZR1,NFKB1,H2AC14,HDAC6,COPS5,SUV39H1,SMAD4,BCL10,SHC1,PRICKLE2,SNRNP70,TIAM1,KPNA1 |
| 3.315e-08 | -17.22 | VAMP7 (vesicle associated membrane protein 7) | protein interactions | 6845 | 112 | 59 | 19454 | 5460 |
RAB3B,KRAS,STX8,SNAP23,STX18,RAB4A,TSPAN3,STX12,SNAP29,RAF1,SPG21,PPP2R1A,MAP1LC3B,SNAP25,RHOH,CGAS,ARF6,VTI1B,STX6,VAMP7,RAB35,HRAS,RAC2,DIPK2A,RHOG,STX1A,RAB5C,LAMP2,LAMP3,NAPG,STX7,TMEM106B,RHOU,RPA3,RAB9A,RAB5A,PMAIP1,STX17,RPA2,PIP4P2,BET1,TMEM231,GINM1,CDC42,RND2,RHOJ,LMBR1L,VAMP3,SLC1A1,CGRRF1,RHOB,LAMTOR1,NAPA,MARCHF3,RAB11A,VAMP5,RAB2A,DNAJC5,BFAR |
| 3.315e-08 | -17.22 | PDE2A (phosphodiesterase 2A) | protein interactions | 5138 | 112 | 59 | 19454 | 5460 |
GALNT1,SDCBP,GHITM,SAMM50,PIP4P2,CAV2,FUT8,MTX2,SEC62,SLC31A1,EMC1,PHB2,VPS28,ABCC5,FADS2,MYH2,TTC1,CISD1,ATG3,EPHA2,TMED5,EPS8,STX16,MLF2,CHMP5,CHCHD3,CDIPT,STX10,TFRC,TMEM165,PTRH2,RNF121,SLC25A20,SLC25A24,TOP3B,MTARC2,HUWE1,TOM1,PDE2A,RNF26,HS2ST1,LPCAT3,PLSCR1,TMED1,TMX3,PEDS1,BCL2L1,RELL1,ATG9A,MOV10,SLC38A7,ORMDL3,PLSCR3,CAV1,CHMP2A,GLT8D1,CCDC127,UBE2G2,TSG101 |
| 3.344e-08 | -17.21 | PRDX1 (peroxiredoxin 1) | protein interactions | 5052 | 320 | 135 | 19454 | 5460 |
ISG15,PPP2R1A,SOX2,MSX2,B3GNT2,EZH2,NME1,CHMP4C,UBE3A,G3BP1,TNF,TRIM26,TRIM37,HNRNPA1,DDRGK1,PRDX1,DCAF4L2,MAGOH,AGR2,TRAF6,FOLR1,PHB1,CACYBP,EGLN3,NPC2,HNRNPL,MPP1,PRDX3,LAP3,PIH1D1,MED31,PPT1,RNF7,ACAA2,CRY1,NMRAL1,HSPA8,COX17,PEBP1,DDX39B,ATP5MK,MED11,UFL1,ADRB2,BTF3,MYC,COX6B1,ACO2,CUL2,RAB11A,CUL3,BAX,RHOB,BRCA1,CMTR1,USP5,PRDX2,ACTB,URM1,MAP1LC3B,UBL4A,INSIG2,TP53,SESN2,RNF8,MYD88,MEPCE,MSH6,PRDX4,NEDD8,COPS5,HDAC6,MPG,TPM3,GAPDH,EMC4,TSNAX,USP15,SHC1,PTGER4,PREP,RAC2,TMPO,CDK9,DCUN1D1,FZR1,CAND1,CDC42,CDK7,GABARAPL2,CFTR,SPR,GSTP1,UBE2M,HEXIM1,WTAP,ACACA,HECTD1,RPA2,CDK1,METTL14,GRM2,UBE2F,PRDX6,RNF113A,DVL2,BAP1,SOD1,RPA3,PML,IRF3,HSPA5,CCR4,NF2,ANAPC15,CFL1,CTSD,CCNB1,CDC73,UBE2H,SPOP,CCDC22,LGALS8,ZBTB18,ACAT1,MACROH2A1,PTEN,MSN,CCNF,EIF4A3,CDC20,DNPH1,VIRMA,TXN,NDN |
| 3.347e-08 | -17.21 | macromolecule modification | biological process | GO:0043412 | 2246 | 773 | 18204 | 5365 |
ELOC,IRF2BP1,TRIM62,SELENOK,TRMT1L,GPAA1,DUSP22,NT5C2,ATG4A,CMTR1,ATG16L1,STK38,FNTB,TYW3,ELP3,UBL4A,CISH,MED30,ANAPC13,OTULIN,ZDHHC4,LIPT2,P3H1,MGAT4A,FUT9,B3GNT2,SPATA2,PML,SNRPD2,IRF2BPL,BMPR1B,TRIB1,TMEM59,RNF40,UBLCP1,TRAF6,CCNF,NAA11,NAE1,NDP,FKTN,NEK2,TPST1,ZDHHC16,TSR3,FAM20B,METTL22,USP30,SENP5,TESK2,STK16,TRIM45,RNF121,GALNT1,MED17,BIRC5,MACROD1,RNF146,DTL,MGAT4B,SNRPB,TRIM21,RAB40AL,LEP,METTL6,CBLL1,SRC,PPIL3,CDK20,SUMO2,PPID,EXT1,GXYLT2,MTMR2,LYPLA1,SPSB3,UBASH3B,EXOSC3,SMUG1,BMPR2,GOLGA7,BMPR1A,UBL5,B4GALT4,PRMT6,GCNT3,FBXO7,NFE2L2,MGAT1,METTL14,NBN,NTRK2,TRIM3,DTWD2,SLC30A5,STYK1,MAN1A2,C1GALT1C1,PIGK,RNF208,COPS7B,NTAQ1,CRTAP,CTNNB1,RPN1,WDR77,PRKD3,NAA16,HSD17B10,RNF103,EP300,TTL,ASB3,SDHAF2,RNF128,PRMT5,MAPK4,RPS27A,DCAF16,GON7,DPH3,UBE2V1,UBE2G2,CDC7,UBE2V2,UGCG,B4GALT7,GSK3A,GALNT17,CAND1,CDKL2,MED31,FBXL19,PTEN,JAK2,TRIM24,MARCHF4,UBE2N,DESI2,WDSUB1,ATG4C,CDK12,UBE2M,CTDSP1,STK26,SKP1,EIF2AK2,RIOK2,VIRMA,UBB,USP2,STAMBP,COPS7A,PI3,KBTBD13,CSK,RNASEL,FGR,UBE2E2,BRAP,UBE3A,RNF14,NIM1K,PELI1,PAK5,TRAF7,OSGEPL1,WSB1,THUMPD1,NEUROD2,GNMT,RNF122,TRIM34,BAP1,NEURL2,IFI27,METTL2A,DPH5,KLHL24,ANAPC2,ELP6,UBE2B,JAK1,SMURF1,PRKX,ETF1,TRIM6,SENP8,TRAF1,FBXO31,TRAF2,RAF1,ROCK2,DDRGK1,MAP3K11,GALNT2,NAA15,APPBP2,DPAGT1,MAPK10,CAB39,RNF182,STX1A,RAB6A,ZDHHC8,ABHD17A,FEM1A,KCTD11,TFB1M,STRADB,OGG1,TRIM23,FBXW11,RAG1,RABGGTB,ATG3,APOBEC3B,USP16,DCUN1D1,PGGT1B,UBE2E3,UFM1,PSMD14,FBXO3,PPIH,POMT2,EDEM2,AIPL1,STK38L,ACVR1,PRKCA,DDR1,KTI12,RNF144B,PGAP4,UBE2D3,EEF1AKMT3,ZNF451,IL21,LCMT1,FBXL7,CDK6,FKBP10,TRIM27,CCL11,ENC1,PTPN11,HUWE1,FGFR1,PTPRQ,NDUFAB1,TTLL10,ITK,EZH2,EDEM3,CEP41,FBXO22,IKBKB,GAPDH,CHCHD4,CUL2,UBE2H,CCNA2,CSNK1A1,B4GALT6,JOSD1,DESI1,ST8SIA4,RNF187,PRKCQ,GOLGA7B,UBR7,HECTD1,RNF20,STK24,COP1,RING1,DTWD1,QPCTL,METAP1,PAK6,SRPK2,SNRPD3,RNF39,KLHL12,DCAF11,CREBBP,UBE2F,ZDHHC24,MPDU1,MARCHF3,QNG1,DYRK1A,USP13,TRIM37,GAL3ST1,PTPN22,COPS5,SUMO1,EEF2KMT,SETD3,SNRPE,RNF126,METTL25B,CTBP1,PRKCB,USP14,EDEM1,CDK7,P4HA2,CSTA,BAZ1B,TRIM22,CDC20,DAPK1,APOBEC3G,PRDX3,SLC35A1,TYW5,FBXO11,CREB1,ANAPC4,WWP2,KLHL7,CTDSP2,WDR45,CDK5R1,NAA50,UBE2A,DAD1,SOCS4,USP15,MED21,OST4,RPS6KA4,MARCHF5,PELI3,CDK1,APOBEC3D,ST3GAL1,LYPLAL1,FKBP1B,NAA60,PIM2,PTPRZ1,CBFB,TNKS,TAB1,VCPKMT,SELENOO,RC3H2,USP8,PPP1CB,COQ8B,MEPCE,TRIM11,PRDX4,SOCS3,PLPP6,TRIM26,RNF113A,MTM1,EGR2,PSEN1,TNKS2,UBE2I,SNRPG,APOBEC3F,WWP1,COPS4,BRCA1,ABHD12,IFIH1,KBTBD6,ASB1,PRKAB1,EGLN3,LACRT,MRM2,YES1,BIRC2,DUSP1,TRMT112,UBE2L3,TRIM32,RLIG1,GLUL,KCTD10,PARP2,WEE2,DCUN1D5,APOBEC3C,ALKBH4,PPIC,STK11,TRIM5,NME2,FBXW7,ZDHHC17,HDAC6,S100A8,DPM2,MED10,ACVR1B,ARFGEF1,SYK,BFAR,PPME1,DCUN1D3,PIGA,CHRM3,MAPKAPK5,CCL2,DUSP6,MGAT5B,RNF26,TBK1,TRMT6,CDK4,PPIF,CSNK1A1L,PIAS1,TRMT10B,PICK1,RNF10,TLR2,MYLIP,CYP1B1,FKBP4,ST8SIA5,APOBEC3A,PPM1M,DMPK,DUSP9,GTDC1,ROCK1,OARD1,LYPLA2,ZC4H2,DPH6,CDC23,MAP3K21,FBXL3,SPOPL,PARP11,RNF41,ANKIB1,TRMT11,ASB11,ADPRH,TRIM35,G2E3,PPM1K,RNF115,METTL21A,PRRT1,CCAR1,CLK1,VRK1,PPM1G,RCE1,PPM1B,NSMCE3,IL15,STT3A,CAMK1,TRUB1,ASB8,AREL1,PIGY,YWHAZ,PRKACB,CDCA3,TRIM10,ZNRF1,ST3GAL5,VKORC1L1,CDK17,SETD4,CUL3,B4GAT1,TNFAIP3,FBXO9,SIRT7,DKC1,CLK4,PPP1R11,FEM1C,UBE2W,WTAP,DNAJC24,FKRP,DUSP26,METTL15,UBA52,DYRK1B,AKT1,SIAH2,KBTBD2,HERC4,PPP3CA,B3GALT2,SPRR1B,SYVN1,CDK5RAP3,DOHH,PRKCE,FN3KRP,EGLN2,SLC25A26,B4GALT1,USP46,FTSJ3,E4F1,PPP3R2,TSG101,PPP5C,UBE2D1,HNRNPAB,TGFBR2,PAK2,TRIM63,SPSB1,KIT,CPE,COQ8A,DOLK,TRAF3IP2,USP38,UBE2K,ZDHHC14,DNTT,ACVR1C,DCAF4,DAPK3,DUS4L,KLHL25,OXSR1,RNF181,CLIP3,UHMK1,AKT3,FUT1,DHPS,PPP1R12A,PPP2CB,HECTD3,HS3ST5,AKT2,COPS2,NUS1,SLC35C1,MED27,PRKAG1,VPS18,DUSP21,PIGW,OTUD6B,NMI,URM1,GFPT1,PAX6,B3GALNT1,UBE2S,TNIK,SRD5A3,ST3GAL2,RAMAC,B3GALT4,RIMKLB,AQP11,PPP2R5A,ZBTB16,METTL18,ATG7,UBA3,HDAC3,ADM2,CDK8,DUSP18,MUL1,PPT1,DUSP10,CSKMT,MED11,KDM2A,EPHB6,HECW1,RNF5,KLHL9,BCKDK,CDK5,STUB1,TNFAIP1,RNF141,ILK,RNF152,CDK9,TOP1,CSNK2B,GGCX,RNF133,MAPKAPK3,OTUD6A,FUT8,SNRPD1,KCTD9,PPM1D,GALNT12,PTAR1,NEK7,FTSJ1,ANAPC16,MAP3K3,SUMO3,VCPIP1,STK4,ST6GAL1,AGA,MPG,PIGC,HENMT1,CDC26,TRMT13,MDM2,TSSK1B,TMEM165,TLR4,ST3GAL4,B3GALT1,FBXO30,CRBN,PTPN1,LARGE1,PPIB,EMG1,ATAT1,RBCK1,TRIM15,PTPN4,SIAH1,TRIM44,RNF139,DET1,WDR6,HINT1,METAP2,GMPPB,PPP2R3A,APOBEC3H,RBM15B,UFL1,TRMT61A,NAA35,PPP2R1A,B4GALT3,PCMTD2,ASB7,CAMKV,PPWD1,ALG2,KLHL22,NQO1,TRIM52,TRIM8,OTUD7B,PGAP2,LORICRIN,TRMT5,AANAT,RNF11,NEDD8,RLIM,GTF2B,DUSP3,ST6GALNAC3,KLHL15,UCHL3,CFAP20,RNF167,MARCHF9,ABHD13,GALNT4,RNF8,ISG15,SEPHS1,FAM20C,FEM1B,MSL2,COL3A1,SNRK,CTU1,VIPAS39,PRMT2,MAP2K1,PPP1CC,OTULINL,OS9,PRPF19,ING5,PPTC7,KDM1A,ANAPC11,XXYLT1,NHP2,RIMKLA,BUD23,TLR7,CTTNBP2NL,FKBP1A,ZBED1,QTRT2,DCAF5,GXYLT1,TNNI3K,TOPORS,ERO1A,PDF,PPIG,ALG11,CBL,PCMTD1,HCST,PTPN5,EXOSC4,CSNK2A1,TMT1A,FZR1,PPIA,ABHD10,SOCS2,PGAP3,PPP2R5E,FBXO32,CSNK1E,RCHY1,MTMR6,IGF1R,CDC16,DYRK2,EPHA4,TRIM68,TLR3,ZDHHC15,TUSC3,OSGEP,SETD7,RNF34,STK3,ETFBKMT,UST,MAP3K12,SHPRH,PMM2,HERC3,FBXO25,USP5,STAMBPL1,RNF7,CSNK1G3,THG1L,TRMO,ALG5,FXN,FAM98A,PDP2,IGFBP3,IL4,TRIM54,KLHL3,SOCS5,NTMT1,SPOP |
| 3.381e-08 | -17.20 | ARF4 (ADP ribosylation factor 4) | protein interactions | 378 | 263 | 115 | 19454 | 5460 |
PTEN,CCNF,SMAP2,SMURF1,VIRMA,LDHA,COPE,CFL1,GORASP2,NONO,SLC25A1,CDC73,AP3S2,ARFGAP3,SQSTM1,ARFIP1,RAB9A,INPPL1,RPA3,HCFC2,TMEM263,CFTR,ATG16L1,RABL3,MET,ACACA,LEMD3,RPA2,LDHAL6B,GOLGA5,HSP90B1,WWP1,STOM,GRM2,FGFR1,MTAP,CDCA3,AIFM1,PTPN1,UBE2N,RCHY1,EPHB6,CDK9,SURF6,CDC5L,ZBTB2,FZR1,ARF6,HDAC6,TSPO,STYK1,IDH1,IGF1R,PC,SFXN1,PSEN1,RHBDD3,MAP1LC3B,WBP11,NECAP2,FBP1,FURIN,TFRC,ARF1,LMBR1L,ESR2,BTF3,PCCB,MYC,CUL3,RAB11A,LDHB,NTRK3,SERPINH1,RIT1,LAMTOR1,HSPA8,PMAIP1,COIL,UFL1,STAU1,ADRB2,DUSP22,TOMM22,BET1,PIH1D1,ARCN1,HP1BP3,STX5,RPL9,RAB35,FOLR1,PHB1,FUBP3,COX14,SUMO2,YWHAG,PPFIBP1,DDRGK1,BABAM1,HNRNPD,YWHAB,AGR2,KRAS,PSMA1,ETFA,TRIM37,SOX2,ISG15,TUBA1A,RAF1,B3GNT2,EZH2,PTRH2,RAB4A |
| 3.434e-08 | -17.19 | COPE (COPI coat complex subunit epsilon) | protein interactions | 11316 | 323 | 136 | 19454 | 5460 |
EEF1G,EMC1,SRSF2,EP300,HSPA8,RPS28,WBP2,DDX39B,ARCN1,VAPB,PRDX3,ATP6AP2,REEP4,TUBB,SPCS1,MATR3,PRDX2,SEC61B,SF3B4,PIGK,ARF1,CDC42EP3,GNG12,NTRK3,SCFD1,RPS5,BRCA1,YWHAZ,CGRRF1,BAG3,SAMHD1,CUL3,TMEM38B,TMED5,RAB18,SACM1L,PSMD12,RPS27A,VDAC1,PSMA1,KRAS,EMC8,RUVBL2,CCT8,MOB3C,SF3B5,PTRH2,CHMP4C,EEF2,SOX2,E2F4,RAF1,HSP90AB1,COX14,SLMAP,ERLIN1,SPTAN1,ZNF511,PHB1,ARL11,RPL23,VPS4A,AGR2,QPCTL,CTNNB1,DDRGK1,WDR11,XPO1,RPL4,FBXW7,CRYL1,TNFAIP1,TMEM263,PPM1G,BAP1,APMAP,LEMD3,HEXIM1,UBE2M,OXSR1,FGFR1,GHITM,LMNA,CDK1,CFTR,CDC42,SPTBN1,VIRMA,TECR,BUB3,COPE,GANAB,COPZ2,FAM210A,METAP2,RPS3,UBE2H,ATP1A1,TUFM,PRDX4,MDC1,RIGI,ARF4,SMIM11,MRPL22,DNAJC30,HUWE1,YIF1A,HSD17B10,BCAP29,SEPTIN7,RAB13,RPL3,NSDHL,NRM,LBR,INSIG2,FAM162A,ILVBL,LMAN1,ARL6IP5,FZR1,HSD17B11,RCHY1,COX4I1,PTPN1,RPL12,OSBPL8,STYK1,SLC35A1,H2AC4,ESYT1,GOLPH3L,GTF2E1,GPRASP2,DHRS7 |
| 3.438e-08 | -17.19 | CSNK1D (casein kinase 1 delta) | protein interactions | 1453 | 249 | 110 | 19454 | 5460 |
TANK,ATP5PO,MFAP1,NUFIP2,CSNK1A1,FOS,HSPA8,CRY1,SNX24,RP2,ZDHHC17,G3BP2,UNC45A,FTL,MYC,RBM15B,BRCA1,YWHAZ,MAF1,SF3B4,RMDN3,FAM83B,USP16,DYNLL1,TAX1BP1,PPP5C,APEX1,RAF1,ARFGAP1,CSNK1E,PPP2R1A,SNAPIN,EZH2,OTULIN,JPT2,TOP2B,LDLRAD4,FAM76B,CDK5,KCTD17,SAV1,YWHAH,XPO1,DBNDD1,CTNNB1,TRA2A,PPM1B,CDC23,GJA1,GATD3,NOB1,HNRNPL,FAM98A,SNX22,ELP3,MRPS34,TOX4,PAK5,DRD3,HEXIM1,UBE2M,DVL2,TEX264,PSEN2,PML,TRIM3,SEC13,FAM110B,CIAO1,ARHGAP21,MECP2,BICD2,TDP1,SMAD2,OPTN,FKBPL,CREB1,PSPC1,CTTN,LURAP1,TMEM74,STOX2,RHOJ,SMURF1,PPP1R10,RPSA,TP53,DDX42,GEMIN7,TAF2,RAD23B,SNIP1,RAB1A,BACE1,MEPCE,ABHD10,PPIL4,KLHL22,ORMDL3,SMAD4,ANKRD49,TUBG1,NPSR1,SMAD3,SSMEM1,FAM199X,DCK,FZR1,MDM2,CDK9 |
| 3.446e-08 | -17.18 | rRNA processing | REACTOME pathways | R-HSA-72312 | 201 | 100 | 10285 | 3229 |
RPS17,EXOSC3,RPS26,RPL8,RPLP2,WDR12,UTP25,RPL27A,THUMPD1,RPLP0,RPS4X,RPL32,FAU,RPL3,RPSA,PNO1,RPS14,RPL7A,RPL24,MRM2,RPS10,UTP6,RRP7A,RPS27L,RIOK2,EXOSC1,RPS15,RPL23,RPS9,MPHOSPH10,TSR3,RPS11,MPHOSPH6,RPS2,NOP58,RPL31,TRMT112,RPL12,EXOSC4,PWP2,RPL19,RPL26L1,RPP14,C1D,RPS28,DKC1,RPL15,KRR1,RPS5,NHP2,NOC4L,HSD17B10,RPS27A,RPL10L,RPS13,ISG20L2,RPS29,RPL13A,RPLP1,EMG1,IMP4,RPP21,BUD23,RPS16,RPS24,RPS20,RCL1,RPL6,RPL28,IMP3,RPL23A,RPL35A,RPL39,RPL26,RPP25,RPS7,RPL10A,CSNK1E,RPL29,RPL7,UBA52,FCF1,RPL37A,RPS23,RPL4,RPL27,TFB1M,RPS12,WDR3,RPL18,RPL9,RPL35,RPL10,NOB1,EXOSC8,RPS3,RPL17,PELP1,RPL22,UTP15 |
| 3.493e-08 | -17.17 | guanyl ribonucleotide binding | molecular function | GO:0032561 | 396 | 169 | 18094 | 5411 |
RIGI,SRP54,EEF1A1,AK3,RIT2,SAMHD1,ARL11,SEPTIN6,ARL6,ARL4D,RHOBTB1,IRGQ,DIRAS3,RAB37,RRAGB,RAB3B,RAB9A,GUCY1B1,RAB31,MRAS,EHD4,ARF6,RAB6A,GTPBP8,RASL10B,DNAJC27,ARL15,GMPPB,DRG1,GNAI3,RAP2B,EEF2,RABL3,MPPED2,RAP1B,GTPBP1,EIF5B,GIMAP4,KRAS,RTCB,TUBA1A,RP2,EHD3,RRAGA,RAB2A,RAB40AL,RAB6B,PDE2A,RASL10A,GTPBP2,MAB21L1,EHD1,TUBG1,RND3,SRPRA,RAB8B,ADSS2,GIMAP2,RAB33A,TUBA1B,ATL1,RASL11A,MX2,RHOU,ARF4,GNAI2,RAN,RAB5C,RAB1B,RAB14,RRAS2,RAB27A,TUFM,NKIRAS1,RAB11A,RAB28,MIEF1,RAB3C,MFN1,RTKN,OLA1,RABL2B,RALA,GNAO1,RAB13,DIRAS2,TRIM23,RHOB,RAB22A,NME2,RAB33B,RND2,RAP2A,RAB19,UCP2,HRAS,NOA1,MTG2,GFM1,ARF1,NME1,RAB3A,RAB32,IFT22,ARL5B,MX1,GNA11,SRPRB,EIF2B2,RASL12,RAB5A,RAC2,RHOJ,DAPK1,RAB39B,RALB,UPRT,LANCL2,RAB29,NKIRAS2,MTG1,RHOG,SAR1B,ARL10,RAP2C,RHOH,GPN2,SCG5,RAB9B,SEPHS1,FKBP4,TUBB,RAB11B,GNAQ,NUDT2,CGAS,DIRAS1,RAP1A,RIT1,ARL4A,AGAP2,CDC42,ERAS,THG1L,RERG,DRG2,RAB23,DNM2,NPR2,PCK2,GNL1,MMAA,FPGT,GNAZ,RAB35,RAB1A,RHEB,GNA14,SUCLG2,SEPTIN7,RAB30,RAB3D,RAB18,RASD1,TUBB4B,HSP90AA1,AGAP1,RAB4A,GFM2 |
| 3.493e-08 | -17.17 | guanyl nucleotide binding | molecular function | GO:0019001 | 396 | 169 | 18094 | 5411 |
RAB19,RAP2A,RND2,RAB33B,UCP2,HRAS,TRIM23,DIRAS2,RAB13,RALA,GNAO1,RABL2B,RAB22A,NME2,RHOB,NME1,RAB3A,RAB32,MTG2,NOA1,ARF1,GFM1,UPRT,RALB,RAB39B,DAPK1,RHOJ,RAB29,LANCL2,RAB5A,RASL12,EIF2B2,SRPRB,MX1,GNA11,IFT22,ARL5B,RAC2,SCG5,GPN2,RHOH,SEPHS1,RAB9B,MTG1,NKIRAS2,RAP2C,ARL10,SAR1B,RHOG,ERAS,CDC42,AGAP2,RAP1A,ARL4A,RIT1,DIRAS1,DRG2,RERG,THG1L,RAB11B,FKBP4,TUBB,NUDT2,CGAS,GNAQ,NPR2,PCK2,DNM2,RAB23,RAB35,MMAA,GNL1,GNAZ,FPGT,TUBB4B,RASD1,RAB4A,GFM2,HSP90AA1,AGAP1,GNA14,RHEB,RAB1A,RAB3D,RAB18,SEPTIN7,RAB30,SUCLG2,ARL11,SAMHD1,RHOBTB1,ARL4D,ARL6,SEPTIN6,SRP54,RIGI,RIT2,AK3,EEF1A1,RAB31,GUCY1B1,RAB9A,EHD4,MRAS,RRAGB,RAB37,DIRAS3,IRGQ,RAB3B,DNAJC27,RASL10B,GTPBP8,GNAI3,DRG1,ARL15,GMPPB,ARF6,RAB6A,EIF5B,GTPBP1,RAP1B,KRAS,GIMAP4,EEF2,RAP2B,MPPED2,RABL3,RAB6B,RAB40AL,RAB2A,GTPBP2,RASL10A,PDE2A,RP2,RTCB,TUBA1A,RRAGA,EHD3,GIMAP2,RAB8B,ADSS2,MX2,RASL11A,ATL1,TUBA1B,RAB33A,TUBG1,EHD1,MAB21L1,SRPRA,RND3,RAB1B,RAB5C,RAN,RRAS2,RAB14,ARF4,GNAI2,RHOU,MIEF1,RAB28,RAB11A,OLA1,MFN1,RTKN,RAB3C,RAB27A,NKIRAS1,TUFM |
| 3.615e-08 | -17.14 | ADRM1 (ADRM1 26S proteasome ubiquitin receptor) | protein interactions | 11047 | 252 | 111 | 19454 | 5460 |
MYL12A,FZR1,PSMB1,PREP,UBE2N,AIFM1,MAP4,USP15,TSNAX,PSMD7,CCDC92,NFKB1,RIGI,FKBP8,VTA1,PSMA5,HUWE1,SEM1,PSME1,RAB1A,RAD23B,PSMC3,TMEM31,UBR7,EEF1A1,INSIG2,SMURF1,UBB,ADRM1,SGTA,RPS20,PSMC5,GANAB,PSMA6,STUB1,CCNF,NAPA,USP14,PSMB2,HSPA5,SMC4,SQSTM1,PRPF4,BAP1,SOD1,ACACA,UBE2M,GRM2,UBLCP1,PAAF1,CFTR,MX1,CDC42,UBA52,ATG16L1,PSMC4,HSP90AB1,DHX15,EGLN3,DYNC1I2,CCAR2,RPS10,PSMB5,PPP2CB,PSMB4,YWHAB,PSMD10,PSMD3,AHCYL1,RPS27A,PSMD12,RUVBL1,PSMA1,PSMA2,HNRNPF,RBBP7,UBE3A,RPAP3,RUVBL2,PABPC1,MTA2,PLS3,RPN1,ISG15,PPP2R1A,ESR2,PSMB6,PSMD6,RBBP4,PSMD4,PRMT5,SNRPD2,LMBR1L,HSP90AA1,ATG3,PSMD14,BRCA1,PSMD1,PSMA4,PSMC1,DDI1,MCMBP,PSMA3,EP300,TXNL1,HSPA8,BIRC2,XRCC5,PSMB7,PPP1CB,PSMB3 |
| 3.680e-08 | -17.12 | NISCH (nischarin) | protein interactions | 11188 | 151 | 74 | 19454 | 5460 |
NTRK2,IGF1R,PCGF3,EPHA4,KRAS,FLOT1,RIGI,UBE2A,MRPS17,ODAM,TOP3B,LGR4,RAB4A,TFRC,RND3,RAB35,SRP14,FAM219B,RAC2,GJA1,RHOH,ARF6,CAV1,DIRAS3,EGLN3,DPP4,LAMP2,PIK3R1,LAMP3,PTGER4,RHOG,IGFBP4,STYK1,HAX1,GID8,CNKSR3,RPA3,BAP1,RHOU,NUP50,RAB5A,RAB9A,ATP6V1G2,PIK3R2,SLC31A1,HSCB,RGS2,PSMC1,RND2,LEAP2,CDC42,FGFR1,CTBP1,UBE2M,LMBR1L,RHOJ,MANSC1,ESR2,RPL19,BTG3,CUL3,PIK3R3,RAB11A,RAB2A,PNOC,CREBBP,USP14,DNAJC5,AR,RHOB,YWHAZ,LAMTOR1,EPHA2,NTRK3 |
| 3.690e-08 | -17.12 | SRPRA (SRP receptor subunit alpha) | protein interactions | 6734 | 269 | 117 | 19454 | 5460 |
AQP3,RAB4A,TMEM182,RPN1,STIM1,MOB3C,PLD3,NAA15,RAF1,TUBA1A,DNAJC25,KRAS,G3BP1,SAR1B,TMT1A,CYP2C9,RPL31,RHOG,RAB5C,LAMP2,DDRGK1,IQSEC1,COX14,TMEM237,DUSP6,PLAC9,RAB35,SSR2,CYB5A,GJA1,PRSS23,BET1,EDEM3,DUSP22,SEC62,RND2,OTULINL,STAU1,HSCB,STX7,PXMP2,ZDHHC17,RAB5A,LMNB1,FAS,ATP1A3,THTPA,PDF,NTRK3,RAB11A,RUSC2,CUL3,MYC,GGH,FBXO22,RPL19,MAD2L2,ESR2,RPL10,LMBR1L,SEC61B,RMDN3,TFRC,SRP72,CCDC47,UBL4A,SRPRB,RAB3B,RIGI,FKBP8,IGF1R,LRRN4CL,ESYT1,POR,STYK1,RPL10A,SLC25A46,DPP4,COPS5,LAMP3,HDAC6,SPPL3,ARF6,FZR1,DNAJC1,RPS16,TMPO,STX6,RBM42,LMAN1,SRPRA,CD274,PTPN1,RAC2,GATAD1,HSD17B11,FGFR1,SSR1,GP9,LMNA,RPA2,UBE2M,ST7,CDC42,RPL4,NF2,PML,SLC39A9,RPA3,DERL1,RAB9A,SQSTM1,SYVN1,SYP,SEC63,VIRMA,PSPC1 |
| 3.717e-08 | -17.11 | CSNK1A1 (casein kinase 1 alpha 1) | protein interactions | 1452 | 364 | 150 | 19454 | 5460 |
GFPT1,SOX2,H1-3,TRAF2,CSNK1E,RAF1,TOP3B,SF3B5,SKA3,RPN1,RUVBL2,HSPD1,IMPA2,RAB18,KRAS,DDRGK1,CTNNB1,DBNDD1,NOL4,XPO1,YWHAG,YWHAH,PPP2R5A,DDX1,MT1X,AHSA1,AGR2,ATP6V1A,FABP5,HSP90AB1,CACYBP,EGLN3,DBR1,HNRNPL,TTC9C,PPP1CB,IDH3B,TANK,UBAC2,MAP2K1,NMRAL1,SF3B1,RPS28,FTL,UNC45A,SNX24,CPSF2,HNRNPC,HNF1B,MYC,NLRP3,HSP90AA1,YWHAZ,RHOB,FAS,LAMTOR1,FAM83A,FAM83B,NFKBIA,CPSF1,SNRPB2,ESR2,LGALS3,ACTB,DYNLL1,TUBB,STAT1,ATP5F1B,MAP1LC3B,LBR,CHRM3,TP53,NUPR1,NDUFS3,RPL3,PTGES3,RIGI,BACH1,KPNA2,DNAAF10,MZT2B,KLHL22,COPS5,GMPPB,DPP4,USP15,TIAM1,BCL10,TUBG1,ANKRD49,CRBN,DCK,SEC23A,NDUFB4,SSMEM1,TMPO,CDK9,MDM2,EIF2B5,FZR1,SPPL3,KCTD3,CAND1,SNX22,EIF3J,WSB1,PIP5K1A,ATG16L1,CPSF4,ACACA,LMNA,CSNK1A1L,RPA2,SQSTM1,RNF113A,PSEN2,DDX46,RPL27,TEX264,DVL2,RPA3,MARS1,MBD3,FBXW7,HMGB1,RPL4,KDM1A,AR,PPP1CC,ATP5F1A,SEC13,MAT2A,SLC25A1,UBE2H,ATP1A1,STK11,NRP1,NCKIPSD,LRP6,PIP4K2C,PTEN,PSMC5,SEC61A1,WDR45,TNFRSF1B,FKBPL,STUB1,RPS3,CCNF,SH3BP4 |
| 3.752e-08 | -17.10 | PTBP1 (polypyrimidine tract binding protein 1) | protein interactions | 5725 | 414 | 167 | 19454 | 5460 |
ERCC3,MOV10,COPS5,HDAC6,SNRNP70,MIR34A,RCHY1,MIR106B,MIR25,EIF2B2,MIRLET7G,FZR1,NAT2,CAND1,CDC5L,TOMM70,TMPO,CDK9,MIR429,MDM2,RPSA,MIR200C,MIR15A,DUSP1,MIR20A,MIR17,ILF2,PPP1R12A,MIR200A,RAB1A,HSD17B10,MIR9-3,HNRNPK,VRK1,RIGI,MIR16-2,MIRLET7C,RAB2A,NONO,AR,TUFM,ATP5F1A,RC3H2,MIR145,SPOP,UBE2H,ATP1A1,IGF2BP1,CTTN,MIR16-1,CCNF,ACAT1,GSK3A,EIF4H,KCTD9,NDN,SRPK2,VIRMA,ATG16L1,RBFOX2,MIR34B,UBLCP1,CDK7,MIR1-2,CCNH,METTL14,GRM2,RPA2,MIR7-1,MIR21,UBE2M,HEXIM1,MIR205,MIR10B,BAP1,RPA3,RNF113A,MIR34C,MIRLET7I,MIR7-3,FBXW7,PDHB,HSPA5,MIR107,MIR29A,MIR143,STOML2,WWP2,HMGA1,DDRGK1,HNRNPA1,MIR29C,MIR31,AGR2,DDX23,RHOG,MIR140,HSPB1,MIR221,MIR1-1,HNRNPD,MIR7-2,PHB1,MIR141,MIR214,EED,SPTAN1,MIR9-1,SUMO2,HNRNPL,MED9,B3GNT2,RAF1,RPS7,MSX2,LGR4,ISG15,MIR222,SOX2,PDHA1,CHMP4C,NGB,RHOBTB1,ABCF1,MIR9-2,HNRNPA2B1,TRIP4,DNTT,MIR206,MIR155,TRIM37,G3BP1,DHX16,HNRNPF,HNRNPDL,CUL3,HNRNPAB,MYC,MIR98,BTF3,PSMD14,BRCA1,RHOB,MIR363,CMTR1,FAU,ARF1,MIRLET7B,ZMYM2,SNRNP40,MATR3,ATP5F1B,MIRLET7D,TIMM13,PIH1D1,SNRPA,DDX39B,PSMA3,EP300,HDAC5,CRY1,PHB2,STAU1,TMEM177,HNRNPA0,UFL1,MIR106A |
| 3.809e-08 | -17.08 | regulation of endothelial cell proliferation | biological process | GO:0001936 | 186 | 90 | 18204 | 5365 |
ATP5F1A,VASH1,TNFSF12,PRL,FGFR1,ANGPT1,FUT1,APLN,IL12A,SCG2,AKT3,MIR132,CCL11,MIR10A,LEP,VEGFC,APLNR,EMC10,KRIT1,MIR133B,POLD4,IL12B,MIR126,SYNJ2BP,MIR15A,MIR34A,MIR135B,MIR193A,MIR30E,RGCC,MIR342,SLC39A9,PPARG,MIR503,SP1,MIR149,MIR146A,MIR30B,FGFBP1,MIR21,CAV1,VEGFA,MIR129-1,MEF2C,MIR150,MIR29A,FGF7,HMGB1,FGF16,MIR205,MIR495,AKT1,CXCL12,MIR152,CDH13,MIR98,SEMA5A,MIR23A,PROX1,MIR361,PDCD10,TNF,CCR3,IL10,MIR24-1,MIR101-1,DBH,FGF10,EGFL7,CCL24,PROK1,GHRL,PRKCA,MIR222,AGGF1,MIRLET7B,MIR130A,ATP5IF1,MIR492,STAT5A,MIR497,CCL2,MIR29C,MIR200C,CAV2,NRP1,STAT1,MIR16-1,MIR10B,MIR424 |
| 3.834e-08 | -17.08 | STAU2 (staufen double-stranded RNA binding protein 2) | protein interactions | 27067 | 216 | 98 | 19454 | 5460 |
FGFBP1,PRKRA,GSK3A,EIF2AK2,TNFRSF1B,RPS3,RPL13A,RPL26,RPL7A,CIAO1,IGF2BP1,ELAVL2,RC3H2,RNF113A,PML,RPA3,BAP1,DGCR8,RBMS2,FGF13,ATG16L1,RPLP0,RPA2,PRR3,KRR1,SYNCRIP,SRP14,SURF6,ZBTB2,CGAS,RPS16,FZR1,E4F1,COPS5,FAM20C,GRSF1,MOV10,RPL10A,RPS2,DHX9,RPL3,RPL23A,MAP1B,RPL17,RIGI,APOBEC3D,RPSA,STRBP,SRP72,ILF2,DNAJC2,RPL37A,RPL10,RPL19,ESR2,RPL35,RPF1,ACTB,MATR3,ZNF668,HNRNPC,OST4,MYC,H1-1,ZCRB1,DCAF4,HSPA8,EXD2,FTL,STAU1,NOP53,PABPC5,LARP4B,SRSF1,RPL8,LYAR,PAIP1,RPS10,DDRGK1,CPEB1,RPL6,WWP2,DICER1,DRG1,TRIM11,SRSF7,LSM14A,PABPC1,PPAN,RPL31,RPL28,NUP42,G3BP1,SOX2,TRAF2,RAF1,B3GNT2,RPN1 |
| 3.852e-08 | -17.07 | Major pathway of rRNA processing in the nucleolus and cytosol | REACTOME pathways | R-HSA-6791226 | 179 | 91 | 10285 | 3229 |
RPL35,RPL10,RPL22,UTP15,PELP1,RPL17,RPS3,NOB1,EXOSC8,RPL18,RPL9,WDR3,RPL37A,UBA52,RPL7,FCF1,RPL27,RPS12,RPL4,RPS23,RPP25,RPL26,RPS7,RPL39,RPL29,CSNK1E,RPL10A,RPL23A,IMP3,RPL28,RPL35A,RPS24,RPS16,RPP21,RPL6,RCL1,RPS20,RPS13,RPL10L,RPS27A,IMP4,EMG1,RPLP1,RPS29,RPL13A,ISG20L2,RPL15,C1D,RPS28,NOC4L,KRR1,RPS5,RPL26L1,RPL19,RPP14,RPL31,NOP58,PWP2,EXOSC4,RPL12,MPHOSPH10,RPS9,RPS2,MPHOSPH6,RPS11,RIOK2,EXOSC1,RRP7A,RPS27L,UTP6,RPS10,RPS15,RPL23,RPL7A,RPS14,RPL24,RPL3,RPL32,FAU,PNO1,RPSA,RPL27A,RPS4X,RPLP0,EXOSC3,RPS26,RPS17,UTP25,RPLP2,WDR12,RPL8 |
| 3.903e-08 | -17.06 | SSRP1 (structure specific recognition protein 1) | protein interactions | 6749 | 662 | 249 | 19454 | 5460 |
WDR82,EED,CCDC71,RPRD1A,MACROD1,COMMD6,SUMO2,LYAR,RAB1B,HNRNPL,CTNNB1,DDRGK1,YWHAH,XPO1,WWP2,IFI16,MAGOH,MGMT,PABPC1,TOP2B,HNRNPDL,RPS4X,CCAR1,HMGN4,VDAC1,SOX2,ISG15,NCSTN,DHX38,SUPT5H,TOP3B,RHOBTB1,APTX,AAMP,MTA2,SMARCB1,RND3,H2BC1,INTS10,POLR2B,PSMD6,SNRNP40,MATR3,CAVIN2,BTF3,ATG101,HNRNPC,MYC,RCL1,DNAJB6,THOC6,CHTOP,EP300,DDX5,HSPA8,SF3B1,XRCC5,DDX39B,SNRPA,RFC4,GINS3,SAP18,UFL1,HNRNPA0,TRA2B,ZC3H14,NCOA5,CD4,ALYREF,SSBP1,SYNCRIP,DKC1,CAND1,CSNK2A1,COPS5,AKAP8L,CHCHD1,H2AC4,SNRNP70,POLB,DHX9,SNIP1,MNAT1,HNRNPK,CHMP1B,H3C1,H2AX,TP53,SRFBP1,FURIN,DDX42,CBX3,INTS12,ZNF655,FGFBP1,PHAX,CSNK2B,ZNF330,LIG3,PPP1R10,SMURF1,SUB1,SMARCA5,UBE2H,IGF2BP1,CHRAC1,LSM6,NLE1,BANF1,BAP1,HSPA5,RBM22,ING5,PPP1R8,SUMO1,INTS6L,HEXIM1,RNF146,ZNF326,RPA2,RPRD1B,H2BC11,PBDC1,PPP2CB,CNTROB,TRA2A,WDR11,HNRNPA1,DPY30,PRPF19,PIK3R1,HNRNPD,PPM1B,DROSHA,SKIC8,DDX23,PCNA,HNRNPA2B1,NEK9,GOLGA7,RFC3,RFC2,PPWD1,MCM6,ZNF592,JUN,E2F4,ANP32A,RAF1,B3GNT2,FEN1,POLR2C,POLR2D,CHMP4C,EZH2,ZMAT2,SNRPD2,SNRPD1,RSRC1,RAN,CPSF1,ZNF22,FAU,PRRC2A,ERH,RBBP4,MCM4,MCM3,RFC5,PRPF31,AUH,BRCA1,DCAF4,FAS,FYTTD1,JADE1,COMMD2,POLA2,COIL,UCHL3,SUPT4H1,PPP1CB,RND2,ACTL6A,ADNP,APOBEC3C,USP39,RCHY1,H2AZ1,ZBTB2,POLE3,FAM118B,CDK9,NCBP2,TOP1,THOC1,HDAC6,SETD5,GRSF1,CALR,H2AC14,BRD3,EMX2,RING1,ZC3H11A,PQBP1,RAB1A,MSH6,POLL,VRK1,THRAP3,LSM4,DDX39A,CD2BP2,MTA3,H2AJ,POLR2G,ILF2,GINS4,PTEN,TRIM24,UBE2I,EIF4A3,VIRMA,MAGOHB,USP14,PPP1CC,AR,ZNF687,NRP1,CDC73,TDP1,MTDH,PPIH,PRPF4,PRIM2,RPA3,MBD3,FBXW7,HMGB1,NF2,CDK7,TXNL4A,MACROH2A2,WTAP,HNRNPH3,LSM2,LMNA,TOX4 |
| 3.933e-08 | -17.05 | SCF(Skp2)-mediated degradation of p27/p21 | REACTOME pathways | R-HSA-187577 | 61 | 40 | 10285 | 3229 |
PSMD12,CDKN1B,PSMC1,PSMC4,CDK4,PSMB5,PSMA3,CDKN1A,PSMB1,PSMD3,PSMB7,PSMB3,PSMA6,PSMB6,PSMA2,PSMD1,PSMB2,PSMC5,PSMB10,PSMA5,PSMA4,PSMD7,PSMB9,SEM1,PSMD6,SKP1,PSMB4,CCND1,PSME1,PSMD10,PSME2,UBB,PSMD4,CKS1B,CCNA2,UBA52,RPS27A,PSMA1,PSMD14,PSMC3 |
| 3.956e-08 | -17.05 | CALR (calreticulin) | protein interactions | 811 | 376 | 154 | 19454 | 5460 |
TPM3,EMC4,EDEM1,FAM20C,PGAM1,CALR,DPP4,SLC2A1,COX4I1,EFNA3,HRAS,CD274,TOMM70,MYL12A,PRNP,MIF,H2AX,NAA35,SH3GLB1,PPME1,ARPC3,NDUFS3,ACTR2,HSPA13,EMC2,THG1L,PTGES3,H2BC14,VWF,DNAJC30,TF,HSPE1,HUWE1,AR,SLC6A4,PTPN11,FLRT3,CALU,UBE2H,CDC73,DNAJC10,PPTC7,MSN,TRIM24,INHA,GANAB,PSMA6,ENO1,RPS3,PLP1,UQCRC2,CCNF,VIRMA,SFRP4,CTSB,EIF3J,CFTR,TPT1,CYC1,UBE2M,PDIA2,MET,PTPN22,METTL14,GRM2,HSP90B1,COX6C,RPRD1B,LMNA,ACP5,SQSTM1,PGK1,NOG,WNT7A,SIRT7,BAP1,RPA3,SOD1,HSPA5,B2M,PDHB,HNRNPA1,PPIB,PFDN5,PDIA3,DRG1,HSPB1,PEX3,AGR2,PHB1,HSP90AB1,CHI3L1,SUMO2,HYPK,DNAJB9,LGR4,EEF2,ASPM,SOX2,E2F4,NAA15,B3GNT2,RAF1,SMARCB1,PDHA1,CHMP4C,EZH2,ERP29,PDIA6,UBE3A,TRIM21,PCNA,EWSR1,PABPC1,NDUFA4,IMMP2L,ANP32B,RNF26,SSRP1,KRAS,GGH,TOMM40,PDE4B,CUL3,SERPINH1,CKB,SEC61B,ENO2,LRIF1,MBL2,BMP1,ATP5F1B,MATR3,EDEM3,PRDX3,TSHR,TOMM22,KLF3,PSMA3,HADHA,EP300,AKAP1,TAPBP,CD1D,ATP5IF1,TMEM106B,PEBP1,DDX39B,DNAJC3,CD40,ITGAV,PXMP2,NDUFS2,EMC1 |
| 3.956e-08 | -17.05 | LNPEP (leucyl and cystinyl aminopeptidase) | protein interactions | 4012 | 186 | 87 | 19454 | 5460 |
TFRC,SFTPC,DNAJC2,MGARP,RAB3B,TNKS2,DPP4,LAMP3,SCGB1D1,DNAJC1,ARF6,LMAN1,STX6,DUOXA2,CAV1,HRAS,SSMEM1,HSD17B11,STARD3NL,TNKS,RAC2,SSR1,STOM,SLC35E3,GTF2H4,ATG16L1,CDC42,ST8SIA4,RPA3,RHOU,SLC39A9,TMEM263,RAB9A,SDF2L1,LGALS8,RAB2A,DNAJC5,RHOJ,VIRMA,DYRK1A,RAB4A,AQP3,DNAJC25,KRAS,TNF,SIAE,TMT1A,GPHA2,EWSR1,RHOG,DROSHA,SMAD9,ATG9A,LAMP2,RAB5C,CST3,FATE1,DNAJB9,RHOH,DIRAS3,TLCD4,RAB35,GJA1,CLDN4,BET1,RND2,OTULINL,SEC62,PRDX3,GLRA2,STX7,TMEM106B,RAB5A,GCC1,LAMTOR1,RHOB,FCER1G,MYO6,CGRRF1,PNOC,RAB11A,REEP4,LGALS3,S1PR4,CYB5R3,GGT7,SEC61B |
| 4.056e-08 | -17.02 | ACTR2 (actin related protein 2) | protein interactions | 10097 | 295 | 126 | 19454 | 5460 |
YWHAB,BCL2L1,HNRNPD,CRTAP,AGR2,FKBP4,ARL14EP,ACTR3B,XPO1,YWHAG,ATG7,YWHAH,CCT7,CACYBP,EGLN3,PPIA,TCP1,CORO1C,PHB1,RPRD1A,CHMP4C,EZH2,ACTN4,NUDCD3,CRTC2,RANBP1,TOP3B,ANP32A,ANP32B,TRIM37,RUVBL1,KRAS,UFM1,RTCB,CCT8,VMP1,OSGEP,PFDN2,MYO6,YWHAZ,RBM27,BLVRA,CCT2,BTF3,PSMA4,CUL3,MYC,ATP6AP2,ESR2,TOM1L1,ACTB,RBBP4,PRDX2,SURF2,EFHD2,PIH1D1,KLC2,ELF5,STXBP1,PPP1CB,STAU1,EP300,STK26,HSPA8,TRAPPC4,PSMD7,H2AC4,NME2,GAPDH,HDAC6,BAK1,CALR,DPP4,CDC5L,TMPO,ESD,ARL6IP5,UBE2N,HCLS1,TBC1D4,NUPR1,SH3GLB1,PPME1,CAPZA2,ARPC3,ACTR2,APOO,MAP1LC3B,CCT5,ANGPT1,CAPZA1,PSMB10,WASL,CYBRD1,HSD17B10,PPP1R12A,CALU,MAPRE1,NCKIPSD,PIP4K2C,NIF3L1,AR,CFL1,PRKACB,ARL6IP6,DHPS,VIRMA,SH3BGRL,DAPK1,CTTN,STUB1,ACOX1,CCNF,SCLT1,RPRD1B,P3H1,RPA2,CFTR,CDC42,HSPA5,GRPEL1,FBXW7,ARPC2,SIRT7,BAP1,RPA3 |
| 4.121e-08 | -17.00 | IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1) | protein interactions | 10642 | 477 | 188 | 19454 | 5460 |
COPS5,SNRNP70,RPS2,SYNCRIP,MRPS9,FZR1,CAND1,RPS16,MIRLET7G,RBM42,TMPO,MIR429,STRBP,TP53,DNAJC2,MIR200A,MRPS18B,DHX9,MIR9-3,NEDD8,HNRNPK,MIRLET7C,MEPCE,MIR16-2,RAB2A,SPOP,RC3H2,ELAVL2,UBE2H,PSPC1,MRPS28,MIR34B,AGO1,CDC42,CD2AP,RPA2,ZNF326,MIR21,HEXIM1,KLF4,MIR7-1,HECTD1,BAP1,MIR10B,LSM12,MIR107,MIR29A,IFI16,MIR143,WWP2,RAB5C,XPO1,CPEB1,MIR29C,DDRGK1,CTNNB1,MIR31,MIR221,DDX1,DRG1,MIR140,FUBP3,MIR214,FAM98A,HNRNPL,RAB1B,MIR9-1,TOP3B,SOX2,MIR222,MIR9-2,LSM14A,PABPC1,MIR206,MIR155,NUP42,RPS4X,HNRNPDL,APOBEC3B,MYC,HNRNPC,HNRNPAB,BTF3,SNRPB,SLC30A5,BAG3,ELAVL4,VDAC2,MIRLET7B,MATR3,DUSP14,RPL27A,MTF1,SNRPA,HDAC5,DDX5,EP300,HNRNPA0,UFL1,STAU1,MRPS7,GRSF1,MOV10,HDAC6,MIR34A,MIR106B,ARL10,MIR25,TOP1,CDK9,MRPS23,YTHDF2,MIR200C,MIR15A,MIR20A,MIR17,ILF2,TRAPPC13,FAF1,RAB1A,HAPSTR1,VRK1,RUNX1,PPP1CC,USP14,IVNS1ABP,MIR145,STUB1,MIR16-1,CCNF,PRKRA,TRIM24,PTEN,RPS20,NDN,FERMT2,MIR1-2,RBMS2,MRPS34,GRM2,HAUS2,RPA3,MIR205,MIRLET7I,SQSTM1,MIR34C,NF2,MIR7-3,AATF,HNRNPA1,MRPS26,MIR1-1,HNRNPD,FBXO32,PHB1,MIR7-2,MIR141,RPLP1,KCTD10,B3GNT2,RAF1,CHMP4C,HNRNPA2B1,ZC3H7A,SLC39A7,G3BP1,TNF,SSRP1,FLOT1,CUL2,CUL3,MIR98,DCAF4,MIR363,ILK,LSM14B,UBE2S,RPL37A,SEC61B,MIRLET7D,PRRC2A,CDKN1A,LARP4B,MCRIP2,BIRC2,YTHDF1,MIR106A,G3BP2 |
| 4.169e-08 | -16.99 | membrane protein complex | cellular component | GO:0098796 | 1261 | 452 | 19108 | 5553 |
ITGA2,IKBKB,CLDN4,CAV2,DPP10,UQCRH,TGFBR2,SEC61G,NHERF1,NDUFB7,DERL1,ATP5PD,SPCS1,VTI1B,ATP5MC1,ITGB5,VDAC2,TIMM29,SOCS5,GABRA2,TOMM40L,CHMP4C,TFRC,VAMP2,EMC10,SNX5,CPLX2,KCND3,CACNB3,CDH13,COX7A1,SHC1,FAM8A1,TRAF2,ATP5PB,GNG13,PDIA3,TRAF6,PIGA,SCLT1,CNTFR,NDUFC2,RPN1,IL2RB,KCNS1,INHA,AP1S2,ACVR1B,NDUFA5,COX7B,TLR2,SEC22B,BMPR1B,ACVR1,TIMM17A,GRIA2,NCSTN,OS9,IGF1R,NDUFA2,TRIM27,GNB3,BET1L,SESTD1,COX5A,GRIA1,ARCN1,TRMT10B,RNF139,KCNJ3,SLC1A3,DNAJC19,INSIG2,SGIP1,VPS26B,ARL6,KCNIP2,LRP6,GOSR2,KCNMB1,TOMM70,NDUFAB1,GLRB,ATP6V1C1,ATP1B1,CD79B,KCND2,SMDT1,SDHB,ATP5F1B,TOMM7,NDUFS6,SEC61A1,PHB1,TIMM21,SDHC,VPS26A,LAMTOR3,SLC25A4,CYC1,NDUFV2,PSEN1,CACNB4,FAF2,TRPC1,TAPBP,UQCRC2,ATP1A2,GNG12,SOCS3,STX7,PICALM,ABHD6,STX18,ATP5F1E,GNG7,TOMM40,PSEN2,SPCS2,KCNJ11,KLHL12,FCER1G,SLC6A3,GJA1,KCNK17,COX6B2,GRIK1,MFN1,CISH,SCN2B,LAMTOR2,CTNND1,ATP5MC3,GABRA1,SOCS4,EMC4,BAK1,ITGB8,ATP5MG,SEC63,VAMP7,NCALD,NRBF2,PHB2,ELOVL6,LRRC8B,DRD1,GNAI2,SLC25A5,VPS16,SPCS3,NDUFB10,GNG11,ATP1B3,CSF2,COX4I1,VPS18,UFD1,GOSR1,BIRC2,GNG10,EMC1,ATP5F1A,UQCRC1,OLFM2,STT3A,RAMP3,EMC6,STX10,MPC1,KCNMA1,HSPD1,AP1G2,STX5,CACNG3,ACVR1C,CPLX1,GABRG2,COX6C,CIDEB,TRAF1,CD40,SDCBP,ATP5MK,LY96,GNG2,NDUFA12,AMIGO1,SEC11A,ATP6V1G2,CTTN,RP9,SNX2,USE1,PLP1,VAMP1,YKT6,EPS8,NDUFS8,LRRC8D,NDUFA1,JUP,GNG3,KCNK13,IGF1,UQCC3,GRPEL1,AP5M1,NDUFB8,CHCHD6,SRPRB,KCNA3,ALCAM,PIK3CA,GNA14,GJC1,PSENEN,PRKCA,OSTM1,FKBP1A,AP3S2,CD14,NECAP2,KCNB1,DAG1,VIPAS39,VAC14,DLG4,PIGY,VDAC1,FKBP1B,SNAP25,COX7B2,CHMP1A,GNG5,GLRA1,SOCS2,UQCRQ,KCNAB1,CLBA1,KCNG3,PIGK,LIN7B,CHRNA7,DLG1,ATP1A3,GABRB2,CD4,KCNIP3,CATSPERZ,SEC61B,STX16,CLIC4,COPE,GABBR1,SAMM50,VAMP3,ITGAV,TLR1,HFE,SAR1B,AP5S1,TLR4,STAC3,SYVN1,ATP6V1E2,ATP5PF,BCS1L,SLC38A9,PIGC,NDUFB6,CRB3,B2M,ATP6V1A,CHMP1B,PIK3R2,SLC25A31,TLR6,EMC8,TUSC3,CPLX3,DAD1,TOMM6,SLC1A2,STX6,NECAP1,VPS33A,CHRNB2,ROMO1,DLG3,ABHD12,CORO1C,OST4,PPIF,SNX3,GLRA2,COX4I2,BECN1,EMC2,RHCE,IMMP2L,GJB2,TF,OLFM3,BMPR1A,ATP6V0B,KRT8,GABRB3,EMILIN1,CDH11,TMEM199,NAPG,GNAQ,ATP6V0E1,SYNE4,CAV1,VAMP8,KCNA2,PLN,SNAP29,SRPRA,AFTPH,TMED3,TIMM10,CAV3,MTX2,PIK3CG,NDUFB4,GNB4,S100A10,CD34,UQCR11,LIN7C,ATP5PO,TOMM20,BET1,NDUFB5,CDH8,CTNNA1,KCNQ5,GRPEL2,AP2M1,AGK,GJA10,STX12,CDH7,GP9,CTNNA2,PDSS2,GNB1,APH1A,VPS39,HM13,GNAO1,SNAP23,KCNJ10,CTNNB1,ATP6AP2,FAF1,SUMO1,SNTA1,SEC61A2,CHMP2A,CLIC2,TOMM22,HTRA2,GRM1,STX1A,CHCHD3,LRRC8A,TIMM23,GNA11,ITGA6,SELENOS,SEC13,CACNB2,ATP1A1,FLOT1,TSG101,NDUFA4,NDUFS2,IL6ST,RHAG,GPAA1,KCNH1,GJB1,SEC23A,ATP6V1G1,KCNJ2,KCNMB2,NEO1,SLA2,RAC2,KCNH8,LAMTOR1,DPM2,COX6A2,COPZ2,CHMP2B,STX17,SSPN,STX8,GPR89A,COX8A,JAK2,SYK,SCN1B,CD247,GNGT2,DIPK2A,PIK3R3,PIK3R1,TAPBPL,AP2S1,GNAZ,UBAP1,STX11,SCN3B,IL2RA,ATP6V1D,PDE4B,SNX1,SNX12,AP2A1,AP1M1,TMED7,RNASEK,BAX,NAPA,CD3G,GNAI3,KCNJ8,CFTR,KCNF1,CALR,COX6B1,TBC1D5,NDUFS3,IL6,FAS,EFCAB7,CBL,EMC9,KCNC1,ATP5F1D,LRRC8C,SYNRG,KCNK10,APOO,VPS28,HMGB1,SLC6A6 |
| 4.243e-08 | -16.98 | GARS1 (glycyl-tRNA synthetase 1) | protein interactions | 2617 | 247 | 109 | 19454 | 5460 |
RNF7,PIH1D1,SHMT1,PRDX3,UFL1,STAU1,DDX39B,HSPA8,CRY1,NUP50,TTC1,PSMA3,BRCA1,SP1,MTG2,MYC,AUH,PMPCA,PSMA4,CUL2,UFD1,TAX1BP1,PSMD6,MAT2B,RAN,AP2M1,PLS3,CHMP4C,PDHA1,RAF1,SOX2,GFPT1,DCP2,KRAS,XPNPEP1,HNRNPDL,ZYX,CCT8,PABPC1,HINT2,RHOG,FKBP4,AGR2,HSPB1,PDIA3,XPO1,ATG7,DDRGK1,OSBP,SNX1,DHX15,PSME2,PHB1,CORO1C,GATD3,RPA2,RARS1,HEXIM1,UBE2M,MTRES1,EEF1E1,CAPN1,CFTR,EIF4E,MARS1,HSPA5,PPM1G,RPA3,DVL2,UGDH,BAP1,HSPB2,STK11,UBE2H,MAT2A,CARS1,MTPN,USP14,TUFM,GORASP2,ZNF622,RPGRIP1L,VIRMA,CCNF,CTNNA1,CTTN,GANAB,GTF2A1,APEH,PSMC3,TP53,MRPL11,CCT5,NEDD8,TOM1,MEPCE,RAB1A,NAE1,PSME1,EMC2,KARS1,EMC4,HDAC6,CAND1,PRNP,TMPO,UBE2N,ARMC1,SEC23A |
| 4.251e-08 | -16.97 | protein localization to membrane | biological process | GO:0072657 | 462 | 190 | 18204 | 5365 |
HYCC1,EMC4,EMC2,SLC1A1,RAB29,NSG1,ROMO1,ASB3,ZDHHC24,TIMM10,TOMM22,PEX26,RAMP3,TMEM88,HGS,SLMAP,LRP6,TSPAN15,HPS6,PIP5K1A,TTC8,RER1,STXBP1,RAB13,EMC1,LHFPL4,DLG3,DLG1,TM9SF1,HYCC2,ATP1B1,ARL5B,TIMM8A,SEC61B,TSPAN5,CPE,CAMLG,ATP1B3,TOMM40,FERMT2,RTP4,BAX,FRMD8,SEC61G,LRRC4,ZDHHC14,DPP10,PREPL,ZDHHC15,KCNB1,EMC10,FLOT1,C1QL2,MTCH2,SNAP25,HSP90AA1,INPP5K,ERRFI1,AKT2,CAV3,OPTN,PIGW,TIMM29,CAV1,TNIK,CACNG3,PTN,ARL6IP5,CD81,EHD4,AQP11,VAMP5,TRAM2,KCNIP3,EMP2,SMURF1,HSPA5,CRB3,SEC63,RAB6B,TIMM13,RAB11A,SRP14,RILPL2,RAP1A,CACNB3,SCN3B,ROCK2,SPTBN1,TNF,ADIPOQ,AGER,PLEKHF1,CHRDL1,SSR3,S100A10,TESC,LIN7B,FCHO2,EMC6,RAB11B,UBL4A,EPHA2,RAB6A,GOLPH3L,CDK5,ABHD17A,ZDHHC4,LGI1,FGF13,TIMM8B,SSNA1,RAB31,EHD3,SH3GLB1,ARL6,NETO2,SRPRA,ATG3,TRAM1L1,PSMD10,VAMP2,TOMM20,NHERF1,ATAD1,PEX3,NPTX1,ARF6,EXOC5,PICK1,VAMP3,TRMT10B,NLGN2,GLRB,SEC61A1,LAMTOR1,WDR83OS,SSR2,ZFAND2B,EHD1,SSR1,ROCK1,RAB8B,BCS1L,NLGN1,MADCAM1,SRPRB,SDCBP,CACNB2,TIAM1,SEC23A,RRAGA,TM9SF4,THY1,DLG4,NETO1,TOMM70,TMEM147,LARGE1,ADORA1,C1QL3,P2RY1,TRAM1,RAB32,SYS1,GPHN,SEC61A2,TOMM6,GOLGA7,IKBKB,EMC8,EMC9,MAIP1,SEC62,TPBG,SAMM50,SRP54,GORASP2,SGTA,LIN7C,TOMM7,JUP,GOLGA7B,RAP2A,WDR19,CCDC47,MTX2,SRP72,AGK,F11R |
| 4.295e-08 | -16.96 | MAD2L2 (mitotic arrest deficient 2 like 2) | protein interactions | 10459 | 324 | 136 | 19454 | 5460 |
RAB6A,ZNF428,DET1,PRR5L,PGRMC1,THAP6,SLC25A3,NDUFA5,ATP5PO,VAPB,DCTN3,NUBP2,WBP2,ATP5MK,ARMCX2,NPTN,NDUFS2,GRPR,ATAD1,TOMM40,SLC7A11,HSP90AA1,RIT1,CD226,SNRPD1,ZMYM2,RAN,CBX5,ABHD12,MAD2L1,NDUFAF4,GNB1,PRRC2A,MAD2L2,CHP1,SNRNP40,TIMM21,RPL7L1,NCSTN,RPS7,IFNGR1,ERLIN2,KIF2A,DCAKD,DTWD2,EZH2,EFNB1,HSPD1,NDUFA4,GTF3C3,RAD21,ZBED1,RBBP7,VDAC1,QPCTL,FAM174A,ICAM2,DPY30,RPL23,DICER1,PPM1B,SPINT2,PRCC,PEG10,ERLIN1,GLRX,ELK1,NDUFS8,ZNF511,NOP58,EIF2S1,CCAR2,RPL7,TMEM106A,NTPCR,CIMIP1,SUPT7L,LEMD3,MAIP1,HELLS,POLD2,POLDIP2,MRPL17,GTF2I,RPL26,RUNX1,ATP5F1A,CFL2,TAF5L,SLC25A1,DNAJC19,EIF2S2,TRIM27,ZNF655,UQCRC2,CDIPT,EIF4A3,CDC20,TECR,DTWD1,TRIM54,KCTD9,RPL13A,MAP2K3,H2AX,EEF1A1,ZMYM4,COMTD1,TP53,IPO8,MLLT11,RAD23B,CHAMP1,CBX3,MAD2L1BP,SLC25A11,RPS13,RIGI,CD80,SRPRB,FARSA,LAMP3,CDC42SE2,ORC5,MOV10,ZNF24,SLC2A1,MUL1,SHLD1,COX20,SRPRA,AIFM1,NKIRAS2,FZR1,VTI1B,RPS27L |
| 4.349e-08 | -16.95 | GPX8 (glutathione peroxidase 8 (putative)) | protein interactions | 493869 | 264 | 115 | 19454 | 5460 |
NRM,INSIG2,SELENOK,CCDC47,SFTPC,YIF1A,EMC2,LPAR2,UNC50,ERG28,ERO1A,TMEM50B,STX8,GPR37L1,SGMS2,DNAJC30,TF,TNFSF8,TMBIM6,TMEM107,CD81,TMEM19,ADIPOR2,NFKB1,BTN2A2,AQP2,SLC35A1,KCNJ10,DOLK,TMEM42,TMEM11,FA2H,RPRM,AIG1,CNIH1,VTI1B,ANKRD46,SPPL3,KLRD1,TMEM106A,PLP2,EDDM3B,TIMMDC1,SEC22B,TRAM1L1,GP9,RPA2,TMEM243,TMEM254,RPA3,CLDND1,NINJ1,HMOX2,SLC35B4,VAMP5,MGST2,SDF2L1,HFE,SLC1A1,CYBC1,GXYLT1,CDIPT,VAMP3,CCNF,SERTM1,VKORC1L1,MMD,MGST3,MFSD6,PGAP2,NEU1,TMEM14B,AQP3,PAEP,PLPP6,LEPROTL1,TMEM60,KRAS,SLC38A7,MARCHF5,PMP22,CLEC1A,CFC1,PLPP4,TSPAN18,MFSD5,TMEM97,TSPO2,RAMP3,EGLN3,CD1A,CHST1,TMUB2,CCDC167,PGRMC1,AGTRAP,BET1,GOSR2,FAM3C,TMEM203,TMEM106B,HSCB,GGH,CYB561D2,MYC,DNAJB6,FAXDC2,PLN,CYB561,TMEM229B,SERINC1,ST8SIA5,LMBR1L,MAD2L2,THBD |
| 4.369e-08 | -16.95 | PSEN1 (presenilin 1) | protein interactions | 5663 | 222 | 100 | 19454 | 5460 |
DUOXA2,PSMB1,STT3A,HACD3,HRAS,DNAJC7,RAB3A,PTGER4,ESYT1,GAPDH,CTNND1,ARF4,PSEN1,FKBP8,RDH11,CNOT7,PSMA5,TMEM33,APH1A,SRPRB,DHX9,EMC2,BACE1,PSMC3,CDH8,DNAJC2,MGARP,KCNIP3,SYNGR1,SLC1A1,VAMP3,CTNNA1,TUBA1B,PSMA6,PDCD4,CHCHD4,CFL1,ST13,PSMB2,MLF1,TSPAN5,HSPA5,HMGB1,FBXW7,VIPR1,CYP2C18,PSEN2,FADS2,METTL2A,JUP,SSR1,CHMP1A,FGF13,NDUFS8,RAMP3,STX5,PSMB5,TMEM30A,STX1A,STAMBPL1,BCL2L1,HSPB1,DEGS1,TRAF6,CTNNB1,TAX1BP3,PIK3R1,PSMA2,KRAS,EMC8,ETFA,CDK5,BAG2,CYP2C8,FAF2,NCSTN,ERLIN2,PRDX2,UMPS,RMDN3,S1PR4,LAMTOR1,PSMD14,RHEB,CASP4,ST3GAL1,TXNRD2,PSMA4,PKP4,RAB11A,SKP1,EMC1,PSENEN,SSR3,OXCT1,HSPA8,TOMM22,EFHD1,NOTCH2,PGRMC1 |
| 4.390e-08 | -16.94 | RAB18 (RAB18, member RAS oncogene family) | protein interactions | 22931 | 128 | 65 | 19454 | 5460 |
CNTROB,RAB1B,AGK,LDLR,HSD11B1,PHB1,SLC2A1,RHOG,AGR2,LAMP2,DPP4,FAM174A,ICAM2,G3BP1,TNF,SRPRB,TOLLIP,RAB1A,CCR1,PDE6D,EZH2,GDI2,PPP2R1A,MAP1LC3B,ERRFI1,SRFBP1,RAF1,APLNR,TOM1L1,ESR2,COPE,RHOJ,TAX1BP1,SEC61B,CCNF,ELOVL4,NRP1,FAM107A,FIS1,VMP1,RHOB,GORASP2,MYC,GPR17,CUL3,TACR3,ADRB2,SLC15A1,FLCN,VIPR1,DERL1,SQSTM1,RTN4,AKAP1,BET1L,PEBP1,RPA3,CSNK1A1,ACACA,RPA2,SEC22A,CDC42,YIPF5,CFTR,PTAR1 |
| 4.402e-08 | -16.94 | AUF1 (hnRNP D0) binds and destabilizes mRNA | REACTOME pathways | R-HSA-450408 | 57 | 38 | 10285 | 3229 |
PSMC3,PSMD14,PSMA1,UBA52,RPS27A,HSPA8,PSMD4,UBB,PSMD10,PSME2,PSMD6,PSME1,PSMB4,PSMB9,SEM1,PSMD7,PSMA4,HNRNPD,PSMB11,PSMC5,PSMA5,PSMB10,PSMD1,PSMB2,PSMA2,PSMB6,PSMB3,HSPB1,PABPC1,PSMA6,PSMD3,PSMB7,PSMB1,PSMA3,PSMB5,PSMD12,PSMC4,PSMC1 |
| 4.402e-08 | -16.94 | TMEM17 (transmembrane protein 17) | protein interactions | 200728 | 403 | 163 | 19454 | 5460 |
JUP,SDCBP,SLC12A2,GOLGA5,STOM,LEMD3,RABL3,ARHGAP1,SEC22B,ADIPOR1,SLC7A1,YKT6,FTSJ1,TMEM209,SLC5A6,LIN7C,ITM2B,ARFIP1,SQSTM1,ARFGAP3,ATP1A1,EPHA2,LRP6,RAB2A,RPF2,DEPDC1B,GORASP2,SLC6A6,HMOX2,COPE,YES1,SNX3,FERMT2,VKORC1L1,SEC63,VAMP3,SMAP2,SCAMP2,NECTIN2,STX10,TFRC,EXOC3,NDUFS3,CASK,CCDC47,PREB,UBIAD1,SLC29A1,LBR,RHBDD3,TOLLIP,CTNND1,SLC6A8,NSDHL,STX8,ATP2B4,DLG1,ABCE1,SHISA2,EMC2,YIF1A,SNAP23,SLC35B3,ESYT1,OSBPL8,TMEM199,RELL1,DHRS7,B9D1,HM13,RAB23,STX6,SLC38A2,LMAN1,CAV1,ITGA6,SRPRA,PTPN1,EHBP1,CAMLG,SLC39A10,CDCA3,SEC23A,TMEM115,ARCN1,FAM234A,USP6NL,MTMR6,WDR77,GOSR2,NOTCH2,EHHADH,BET1,EMC1,GOSR1,RER1,STX7,ABCC5,ATP2C1,SLC35F2,BET1L,SPCS3,GCC1,WDR20,SCFD1,SLC38A1,SLC7A11,FAM219A,NSA2,NIBAN2,VEZT,PKP4,BTF3,SLC1A3,STX16,SLC30A5,MB21D2,TVP23B,ATP6AP2,NCKAP1,FAM91A1,CYB5R3,FZD6,GPR89A,STIM1,VAMP2,STX12,AP2S1,HGS,PLD3,NETO2,MARCKSL1,EMC8,SEMA4C,SLC20A2,VAMP8,AHCYL1,TFG,TMEM87A,AKT2,SCYL2,EFNB1,SEC11A,TMEM30A,SLC20A1,PIK3R1,PPFIBP1,YWHAH,DDRGK1,WDR11,TBC1D5,OCRL,MPP1,SNX2,OSBP,NDUFS8,VAMP7,TMEM237,RAB11B,WDR6,TNIK,PTK7,STX5 |
| 4.420e-08 | -16.93 | negative regulation of epithelial cell migration | biological process | GO:0010633 | 118 | 63 | 18204 | 5365 |
MECP2,MIR204,PTEN,MIR137,MIR29C,ATP2B4,MIR200C,MEF2C,MIR424,MIR129-1,MIR16-1,HDAC5,RGCC,IL4,GADD45A,MIR206,JUP,MIR320A,MIR193A,MIR20A,MIR492,MIR146A,CSNK2B,MIR497,MIR21,MIRLET7B,MIR212,MIR130A,PPARG,MIR221,MIR503,MIR149,CXCL13,MIR640,SVBP,MIR24-1,MIR101-1,MIR188,SPRED1,MIR505,PDCD10,TNF,MIR133B,MACIR,STC1,MIR15A,SYNJ2BP,MIR379,MIR885,STARD13,MIR132,VASH1,HMGB1,CORO1C,MIR205,MIR495,ADIPOR1,DUSP10,MIR361,KRIT1,MIR152,KLF4,MIR10A |
| 4.499e-08 | -16.92 | Removal of licensing factors from origins | REACTOME pathways | R-HSA-69300 | 74 | 46 | 10285 | 3229 |
PSMB2,PSMD1,PSMA6,MCM8,CDKN1A,PSMC1,PSMD12,PSMC3,PSMA1,RPS27A,CCNA2,PSMD4,MCM3,PSME2,ORC6,PSMB4,PSMD6,SEM1,FZR1,PSMB9,PSMA4,MCM4,PSMB10,PSMA5,PSMC5,PSMB11,MCM6,PSMA2,PSMB6,PSMB3,PSMB7,PSMD3,PSMB1,PSMB5,PSMA3,ORC5,PSMC4,CDKN1B,GMNN,PSMD14,RB1,UBA52,UBB,PSMD10,PSME1,PSMD7 |
| 4.503e-08 | -16.92 | PSMD10 (proteasome 26S subunit, non-ATPase 10) | protein interactions | 5716 | 181 | 85 | 19454 | 5460 |
RPS14,PSMC4,PSMB3,DDAH1,PPP1CB,PAAF1,UBLCP1,PSMB7,LMNA,MED23,RNF7,MAP2K1,ELOVL1,BAP1,DUSP9,HSPA8,EP300,SQSTM1,PSMA3,DDX5,UFL1,PSMC1,RNF11,MARS1,PSMB2,CUL3,PSMA4,LDB1,PSMD1,USP14,PSMD14,HSP90AA1,UBE2H,CCNF,PSMA6,PSMC5,RPS20,PSMD4,ADRM1,ACTB,PSMD6,PSMB6,SNRPB2,OARD1,TP53,CDK4,TULP3,TMEM31,MAGEA4,PSMC3,RAD23B,CCT8,PSME1,RUVBL2,PCNA,HAPSTR1,UBE3A,SEM1,PSMA2,HNRNPF,PSMA5,PSMA1,PSMD12,NFKB1,KARS1,GRSF1,PSMD3,WWP2,ATG7,ZFAND2B,CCDC92,PSMD7,BECN1,POU5F1,MAP4,AIFM1,PSME2,PSMB4,PSMB5,RB1,PSMB1,OSBP,DYNC1I2,MDM2,DHX15 |
| 4.503e-08 | -16.92 | SCAMP3 (secretory carrier membrane protein 3) | protein interactions | 10067 | 181 | 85 | 19454 | 5460 |
LAMP3,PGAP3,ATG9A,LAMP2,ATP5MG,RAB5C,WWP2,LAMTOR2,RB1CC1,TSG101,GJA1,RAC2,RAB35,HRAS,COQ8A,EGLN3,DIRAS3,RAB11B,ARF6,NCSTN,MAP1LC3B,JUN,TBK1,TP53,HGS,RNF126,OTULIN,PLD3,TSPAN3,PDHA1,RAB4A,RAB1A,SOCS2,SLC6A8,RIGI,KRAS,G3BP1,SRPRB,TOLLIP,RAB3B,BAG3,DNAJC5,SUGP1,RAB2A,RAB11A,TM9SF4,VAMP5,GPBAR1,NRP1,CDC73,EPHA2,LAMTOR1,RHOB,SYNGR1,LMBR1L,OPTN,SCAMP2,TECR,VIRMA,RHOJ,TAX1BP1,CDC42,RND2,CDK7,DUSP22,ATG16L1,BET1,HAUS2,RPA2,KLF3,GPR35,WWP1,VIPR1,NMRAL1,RAB9A,SQSTM1,RAB5A,RNF113A,PMAIP1,BAP1,RPA3,TSPAN15,STX7,HSCB,LPAR1 |
| 4.644e-08 | -16.89 | PSMD13 (proteasome 26S subunit, non-ATPase 13) | protein interactions | 5719 | 287 | 123 | 19454 | 5460 |
PSMA4,MYC,PSMD1,BRCA1,PSMD14,RIT1,SNRPD2,RBBP4,FBXO22,PSMD6,PSMD4,ESR2,PSMB6,PSMB3,PPP1CB,PSMB7,PRKD3,PSMA3,HSPA8,TXNL1,MCMBP,UFL1,HNRNPA0,UNC45A,PSMC1,DDI1,RNF11,IFI16,PSMD3,ATG7,DKK1,PSMD10,TRAF6,AGR2,POU5F1,PSMB4,PHB1,PSMB5,PSME2,DHX15,EGLN3,ISG15,EZH2,PLS3,MOB3C,HNRNPA2B1,CCT8,ABCF1,UBE3A,RUVBL2,PSMA2,HNRNPF,KRAS,PSMA1,SAR1B,PSMD12,RPS27A,PSMB2,USP14,AR,STK24,SPOP,UBE2H,PDCD4,NAPA,CTNNA1,PSMA6,CCNF,MSN,PSMC5,ADRM1,VIRMA,SRPK2,PSMC4,PAAF1,UBLCP1,GRM2,METTL14,RPA2,ACACA,HEXIM1,UBE2M,PRIM2,RPA3,BAP1,DVL2,KARS1,TPM3,ELOC,COPS5,PSMD7,CCDC92,PSMG2,TSNAX,USP15,MAP4,PSMB1,FZR1,CDC5L,INSIG2,MAP1LC3B,EEF1A1,PSMB9,TMEM31,NUPR1,RAD23B,PSMC3,PSME1,RAB1A,MAP1B,DHX9,ABCE1,HAPSTR1,TGFBR2,DNAJC30,CAMK2G,SEM1,PSMA5,HUWE1,FKBP8,MEPCE,VTA1,RNF20 |
| 4.647e-08 | -16.88 | SMCR8 (SMCR8-C9orf72 complex subunit) | protein interactions | 140775 | 123 | 63 | 19454 | 5460 |
CRYAB,FGFR1,SSR1,TOMM22,SEC62,RND2,OTULINL,ST7,PHB2,STX7,PXMP2,TOMM20,FTL,EXD2,RAB9A,MAVS,DERL1,AKAP1,RAB5A,LAMTOR1,FIS1,C9orf72,CDC16,RAB11A,MGST3,RHOJ,SEC63,VIRMA,RMDN3,SEC61B,STIM1,PTRH2,RAB4A,RND3,FURIN,TBK1,MTCH2,DNAJC25,RAB3B,FKBP8,ZYX,TMT1A,RHOG,RB1CC1,LAMP2,SLC25A46,MARCHF5,RAB5C,LAMP3,FEM1B,DNAJC1,RHOH,TMPO,STX6,LMAN1,CAV1,COX14,RAB35,PTPN1,AIFM1,ARL10,HSD17B11,GJA1 |
| 4.694e-08 | -16.87 | endoplasmic reticulum protein-containing complex | cellular component | GO:0140534 | 122 | 64 | 19108 | 5553 |
UFD1,B2M,PIGC,SRPRB,TAPBP,ORMDL3,RPN1,SPTSSB,PDIA3,PIGA,DPM2,EMC9,FAF2,GANAB,SDF2L1,SPCS3,SYVN1,ELOVL6,FAM8A1,SEC61A1,ORMDL1,GPAA1,MZB1,TRAF2,SRPRA,HSP90B1,SPTSSA,SEC63,EMC10,PDIA6,EMC4,RP9,SEC61B,CALR,SELENOS,SEC61A2,UGT1A1,DNAJC10,SEC11A,RINT1,RNF139,OST4,SPCS1,PPIB,EMC2,FAF1,CAMLG,INSIG2,PIGK,TAPBPL,OS9,DERL1,HM13,SEC61G,PIGY,EMC8,HSPA5,EMC1,EMC6,STT3A,DAD1,FKBP1A,SPCS2,TUSC3 |
| 4.755e-08 | -16.86 | MRPS14 (mitochondrial ribosomal protein S14) | protein interactions | 63931 | 214 | 97 | 19454 | 5460 |
MRPL10,KLF12,RBMS2,MPV17,MTRES1,KLF4,MRPS34,FGFR1,GFM1,CRYZ,FBXW7,FBXO7,TUFM,ATP1A1,UBE2H,DNAJC19,MRPS16,RC3H2,MRPS28,CCNF,SRC,RPL13A,APOBEC3D,AURKAIP1,METTL15,MRPL11,TP53,GFM2,RPL23A,RPL3,MRPS18B,SLC25A10,FASTKD5,MRPS18C,MEPCE,RPL17,CTNNBL1,GRSF1,RPS2,NOL12,CHCHD1,SNRNP70,TMEM70,PRR3,TRMT10B,SRP14,SSBP1,MRPS9,RBM42,CDK9,MRPS23,SLC25A12,FGF17,NGRN,EXD2,MRPS7,HSCB,AUH,MTG2,MYC,PMPCA,RIT1,TAFAZZIN,COX16,MRPS25,TACO1,DLST,CCDC90B,RPL10,RPL19,MRPL23,RPL35,JUN,E2F4,MTA2,PDHA1,HINT2,MRPS11,COX8A,SRSF7,HSPD1,RPL31,MRPS17,KRAS,TRA2A,MTRF1,MRPS35,RPL6,RAB5C,MRPS26,RPL23,RHOG,MRPL18,GATD3,SRSF1,RMND1,OCRL |
| 4.769e-08 | -16.86 | Vpu mediated degradation of CD4 | REACTOME pathways | R-HSA-180534 | 53 | 36 | 10285 | 3229 |
PSMB7,PSMD3,PSMB1,CD4,PSMB5,PSMA3,PSMC1,PSMC4,PSMD12,PSMA4,PSMB10,PSMA5,PSMC5,PSMB11,PSMB6,PSMA2,PSMD1,PSMB2,PSMA6,PSMB3,PSMD10,PSME2,PSMB4,PSME1,PSMD6,SKP1,SEM1,PSMB9,PSMD7,PSMC3,PSMD14,PSMA1,RPS27A,UBA52,UBB,PSMD4 |
| 4.769e-08 | -16.86 | Autodegradation of the E3 ubiquitin ligase COP1 | REACTOME pathways | R-HSA-349425 | 53 | 36 | 10285 | 3229 |
PSMB3,PSMA6,PSMB2,PSMD1,PSMA2,PSMB6,PSMB11,PSMC5,PSMA5,PSMB10,PSMA4,PSMD12,PSMC4,COP1,PSMC1,PSMB5,PSMA3,PSMB1,PSMD3,PSMB7,PSMD4,UBB,UBA52,RPS27A,PSMA1,PSMD14,PSMC3,TP53,PSMD7,PSMB9,SEM1,PSMD6,PSME1,PSMB4,PSME2,PSMD10 |
| 4.776e-08 | -16.86 | UTP20 (UTP20 small subunit processome component) | protein interactions | 27340 | 203 | 93 | 19454 | 5460 |
MIR29A,AATF,MIR107,MIR7-3,MIR34C,RNF113A,PPP1R26,MIRLET7I,MIR205,PML,SIRT7,RPA3,MIR10B,MIR7-1,MIR21,RPA2,MIR1-2,CDC42,MIR34B,VIRMA,RHOJ,TMEM74,ZNF330,TNFRSF1B,MIR16-1,MIR145,MIR16-2,MIRLET7C,CD80,MIR9-3,MIR200A,MIR17,MIR20A,MIR200C,MIR15A,MIR429,MIRLET7G,TOP1,MIR25,RAC2,MIR106B,CD274,MIR34A,KPNA1,MIR106A,COIL,STAU1,NPTN,AKAP1,UPF3B,VPS18,RND2,FAM234A,ESR2,EFNA5,MIRLET7D,MIRLET7B,SCN2B,LMBR1L,RIT1,MIR363,RHOB,LMNB1,ATG3,SCN3B,GPR17,MYC,HNRNPDL,MIR155,KRAS,RPS24,MIR206,MIR9-2,RPL31,CYB5B,RPS7,MIR222,MIR9-1,NOP58,MIR214,MIR141,EED,MIR7-2,FBXO32,MIR140,MIR1-1,MIR221,MIR31,DDX23,DDRGK1,MIR29C,MIR143,IFI16 |
| 4.778e-08 | -16.86 | RABAC1 (Rab acceptor 1) | protein interactions | 10567 | 136 | 68 | 19454 | 5460 |
RRAS2,RETREG3,UBE2I,RPS20,NUDT18,CYB5R3,MAD2L1,F11R,RHEB,NTAQ1,KDSR,RAB2A,TRIM32,CREB3,SNX10,NIF3L1,RABAC1,RAB9A,RTN4,RAB5A,TMX2,RPA3,SNX11,RGS2,RNF5,FXR2,SSR3,RER1,TSHR,YIPF5,RAB6A,LEMD3,LMNA,TMEM115,SNX17,HRAS,COQ8A,RAB33A,EPHB6,FHIP1B,CRB3,RAB1B,TMED9,PLEKHF2,SNX1,MIF,RAB22A,FAM241A,EI24,STOML2,TMEM208,RAB5C,RAB3A,TMEM42,CYBRD1,S100B,LTBR,RAB1A,VTA1,RIGI,SPG21,RAP1A,SH3GLB1,ABHD4,TMEM14B,VAMP2,STIM1,RAB4A |
| 4.805e-08 | -16.85 | RIPK4 (receptor interacting serine/threonine kinase 4) | protein interactions | 54101 | 442 | 176 | 19454 | 5460 |
VDAC1,CCT8,ABCF1,PDIA6,RPAP3,RUVBL2,TUBB4B,RANBP1,NAA16,TNPO2,NOB1,HSP90AB1,SDC4,FKBP4,AK2,HSPB1,YWHAB,PADI2,IQSEC1,YWHAH,YWHAG,XPO1,TIMM17A,HIGD2A,JAGN1,PEBP1,STK26,THBS3,HSPA8,CTBP1,SDC2,CSNK1A1,EDEM3,GPC4,POLR2B,PPP5C,VDAC2,FBXW11,CCT2,CIRBP,DNAJB6,H1-1,MLF2,HNRNPK,AKAP12,FKBP8,TRAFD1,SLC16A1,ERO1A,ABCE1,CLPB,TP53,UBL4A,ESS2,RPS27L,CAND1,ESD,TMPO,NDUFB4,UBE2N,COQ8A,KPNA1,AKAP8L,GPRASP2,HSPA5,MAIP1,SMG5,PRDX6,PGK1,LEMD3,TFB1M,NTPCR,CDIPT,UQCRC2,TRAF7,ATP1A1,SLC25A1,PSMB2,TNFAIP3,ST13,MTPN,WDR19,UBE2A,GTF3C3,NDUFA4,HSPD1,SLC25A5,PREPL,BAG2,GPSM3,PCNA,GDI2,RAF1,MARCKSL1,CSNK1E,FAF2,PPP2R1A,AGK,STK3,WDR6,RPLP1,RPLP2,VPS4A,HAX1,AHSA1,RB1CC1,SLC25A21,PIK3R1,RADX,ASB3,SKP1,HADHA,BIRC2,SLC25A3,FKBP1A,PRDX3,TUBB,MRPL23,CHP1,NDUFAF4,PELO,CYB5R3,CD79B,SEC61B,POLR3B,CDC7,YWHAZ,ILK,SCFD1,HSP90AA1,PIK3R3,ACO2,SAMHD1,RFC5,FARSA,THRAP3,HUWE1,PTGES3,DHRS7B,ANKRD6,CCDC47,SLC25A12,TOMM70,AIFM1,SRPRA,COX20,EXOC2,ECD,OSBPL8,DNAJC7,CALR,PID1,HMGB1,ARMCX5,NUCKS1,NF2,GTF2I,SOD1,HELLS,SQSTM1,PRKCB,HSP90B1,CNP,SLC35E1,VIRMA,ZNF507,TECR,TUBA1B,METAP2,STUB1,SFXN2,SDF2L1,NAPA,NDUFB10,TUFM,ATP5F1A |
| 4.842e-08 | -16.84 | DERL1 (derlin 1) | protein interactions | 79139 | 448 | 178 | 19454 | 5460 |
SEC22B,ARHGAP1,RABL3,HSP90B1,SLC12A2,RNF103,TMX4,LMNA,EPHX1,PDCL,FADS2,RPA3,SPCS2,MTDH,RTN4,SYVN1,PRKCB,YKT6,TTR,TMEM209,USP14,HMOX2,ARFGAP3,GGCX,AP2A1,VAMP3,ALB,GANAB,RHOJ,PNP,SEC63,CCDC47,LBR,ABHD4,SRP72,SERPINA1,STX8,NSDHL,TMX3,EMC2,BSCL2,HUWE1,RIGI,EI24,TMEM199,H2AC14,HM13,ESYT1,POR,OSBPL8,EHBP1,PTPN1,SRPRA,HACD3,CDCA3,DERL2,CAV1,PGRMC1,NOTCH2,TOR1AIP2,OTULINL,VAPB,PSMB7,SCN3B,VEZT,LMNB1,VMP1,SCFD1,CYB5R3,FAM177A1,SEC61B,REEP4,ABHD12,ANP32A,MACO1,ERLIN2,FAF2,CYB5R1,PPP2R1A,STIM1,RPN1,SCD5,EMC8,RETREG1,SRSF4,UBXN6,PSMD3,CDK5RAP3,C2CD2L,CYB5A,AGK,NUP35,CACYBP,XBP1,CFTR,TRAM1,USE1,SSR1,RPA2,LEMD3,PML,NLE1,TMX2,TEX264,RNF113A,DERL1,TRIM32,GORASP2,ATP1A1,ATL1,PSMA6,SLC1A1,SEC61A1,SRP54,SLC7A8,SNAP29,PREB,RBM34,PIK3CA,TMEM31,GNAI3,ATP2B4,GAD2,STX18,SRPRB,SLC7A14,NUP107,FKBP8,SELENOS,EDEM1,DHRS7,ZFAND2B,SMIM12,SMCHD1,UBE2N,CAMLG,SLC39A10,SVIP,CAND1,ARL6IP5,DNAJC1,ILVBL,LMAN1,TMPO,SLC38A2,BET1,GOSR2,CNPY3,UBAC2,FDFT1,XRCC5,AKAP1,DDX5,HSPA8,UFL1,EMC1,RNF5,TMEM38B,MYC,PSMD1,LMBR1L,RETREG3,ZMYM2,ATP6AP2,PSMB6,STBD1,PTRH2,TAPT1,RINT1,RUVBL2,NUP42,PSMA1,RAB18,DDRGK1,PEX3,RAB35,STX5,TCP1 |
| 4.881e-08 | -16.84 | homeostatic process | biological process | GO:0042592 | 1456 | 520 | 18204 | 5365 |
FTH1,PRDX3,MYC,SLC6A2,ATP1B3,FLCN,IGF1R,SOS2,RPS14,RMDN3,HCRT,FMO2,KCNB1,NELL2,CCL5,ATP6V0B,FITM2,SLC48A1,RNASEK,MTCH2,TLCD1,SMAD5,ATP6V1D,INPP5K,HTR2A,MIR132,ATP6AP2,KCNJ2,SASH3,CCL3,MEF2C,KCTD17,CAV3,MSTN,FKBP1B,CMA1,WDR37,RC3H2,FTL,PRDX4,ATP6V1A,IFNB1,CAV1,TXNRD2,ATP2C1,PSEN1,MIR146A,MTM1,ATP1A3,AQP3,FXN,CCDC186,IDE,CLDN1,SMAD2,SLC38A3,NPTN,KLHL3,MIR208A,IL20RB,TF,SESN3,TWNK,ATP5F1B,IL1A,CHP1,MIR144,MBD5,KRAS,PLSCR3,POLB,LCA5,SLC31A1,CREBBP,ADRB2,CCR7,ATP6V1G1,FMO1,GLRX2,GCLC,ATP6V1C1,RMI1,COL3A1,NUCKS1,CLRN1,OAS1,FOSL2,PRKCB,CCR1,CAV2,ATP2B4,HPS6,SMAD1,NLRP6,ATP1A2,PICALM,FIS1,ATP1B1,MTF1,BAG3,ERO1A,SOX9,SART3,NDFIP1,SLC30A7,RGN,PRCP,SOD2,SLC39A7,LEPR,MIR34A,EHD1,RHCG,CLIC4,ARF1,SLC39A13,RRAGA,TMEM165,SLC4A10,CYB561,TLR4,DDIT3,LRRC8A,CCL11,MIR590,CCL8,PTPN11,LARGE1,PIWIL4,NKIRAS1,SGIP1,CIAO3,ADORA1,P2RY1,FGFR1,PRDX2,RAC2,COMT,IL7,CHRNA7,ADCK1,HEXB,EZH2,NCSTN,B2M,MIRLET7G,PNPLA4,EGR1,CYP27B1,MKKS,GAPT,APOC2,ARMCX1,SERPINA3,CLN8,CNTN2,EPO,FSTL1,FATE1,FUNDC2,CCDC22,SFRP4,CYP7A1,RACGAP1,SV2B,UFL1,SLC16A1,ACOX1,LIPA,EMX1,PPARG,SUV39H1,PPP2R1A,SESN2,ZNHIT1,CHMP5,NQO1,TSPO,TLCD2,F11R,TRIM6,TMEM106B,RDH12,ATP1A1,CX3CR1,DBH,CX3CL1,ATP6V0E1,RAF1,SLC39A10,PPT1,CYP11B2,ACTB,ADIPOQ,VAPB,AGER,SLC22A17,PLG,SMDT1,MYCT1,ABHD5,CXCL12,RAB11B,BCL6,HFE,KCNMA1,MPIG6B,ORMDL3,HMGB1,CYP4F12,MBL2,CYP11B1,SLC22A12,GPR89A,ANKH,RB1,ADNP,LRRC8D,SLC25A5,NKIRAS2,TRA2B,BOLA1,RAG1,NDN,HSP90B1,SLC29A1,CLDN3,SLC25A27,CCR2,BOLA2B,F2,AIPL1,CEBPG,BOLA3,LDB1,CFTR,GJA1,BGLAP,CFL2,UBB,CAMLG,ADIPOR2,BAX,MIR379,TRAF3IP2,IL6,LAMP2,MIR185,ABHD4,UBE2K,RPS17,LDB2,UBE3A,ACVR1C,STOML2,SLC1A3,GRM1,OXSR1,MT1X,PRNP,ADRB1,E2F4,AKT3,LDLR,CA2,MPV17,CNNM4,FOXP3,DHPS,TRPC1,ERRFI1,VPS33A,MIR33B,CIB2,TP53INP2,NUS1,CMKLR2,NCAPG2,IREB2,BAP1,SNAPIN,PMAIP1,CHMP2B,CD36,TPT1,PNPLA8,SAR1B,AQP2,MIR204,VSTM4,EDNRA,LYAR,PAX6,SIN3A,LPCAT3,DNAJB2,INHA,UBE2S,FABP4,AQP4,CIB3,AQP11,SELENON,POC1B,SLC39A9,RHBG,MIR148A,MAEA,OCIAD2,MCL1,TLR9,PCK2,ORMDL1,RTN4,MLLT6,ILDR1,MT3,GPX1,CTNNB1,TXNRD1,TNFAIP3,RHCE,SLC1A1,RAB3D,RHAG,VDR,TXN,BAK1,CTSK,GSTP1,HYAL2,CALR,BOK,NPC1L1,ATP6V1G2,UCP2,MT1E,DRD3,SELENOS,SMAD4,ACO1,FTHL17,PRND,AKT1,IL1B,P2RY4,MIR182,MINAR2,PPP3CA,SLC4A8,CYB561D2,BAD,ACACA,TUBA1A,CD34,CDK5RAP3,LACC1,EGLN2,CRY1,NR1H2,ACP5,PCSK9,GNB3,JAK2,APOC4,SOD1,SLC8A1,CARTPT,RRN3,TRIM24,NCOA5,TXNRD3,CNR1,ARRDC3,ATP5IF1,CYTL1,PLAA,FRRS1,FAS,KIT,RPL13A,ADRB3,XBP1,CYB5R4,MIR320A,GRIA1,LGR4,MIR15A,CYP39A1,COMMD9,SURF4,NEO1,GPIHBP1,ICAM1,APEX1,SNX10,SLC39A3,NLE1,CACNB2,PIK3CA,KRIT1,PDE4B,TM9SF4,ATF4,TLCD4,LEP,FASLG,SQSTM1,PSEN2,COX11,SLC25A23,SRC,SLC25A46,ANGPT1,EXT1,KCNJ11,PRDX1,PBLD,IL18,SLC41A1,ADGRG1,TMEM199,VEGFA,SIT1,FGF23,SFXN1,SLITRK1,FABP5,ALPL,MAIP1,MT1A,NCDN,NFE2L2,AKR1C1,TLCD3B,RPS24,OPRK1,STIM1,SLC30A5,PRKACB,CCL1,CA12,CCDC47,TRIM10,PIK3R1,KLF1,CLDN12,PIK3R2,NPC2,CLTRN,TFRC,LACRT,SELENOK,CCN3,CYBRD1,TRIM32,GPAM,ESAM,TMOD3,ISCU,KCNJ10,SMAD3,CRTC2,STC1,SLC2A1,SLC7A11,STK11,SELENOT,ADIPOR1,FBXW7,TMEM174,FOXA3,PRDX6,AKR1B1,S100A8,PKNOX1,HDAC6,HSCB,CCL23,TMBIM6,CD40,COX19,CCR4,PROM1,SRI,MT1M,MIR16-1,CACNB4,DRD1,GPRASP2,PML,CLCN6,NPPC,NHERF1,IL2RA,TASL,HCLS1,CCL2,GLRX5,SLC11A2,DISC1,BPGM,NPTX1,TMEM97,GRM2,MT2A,CCL19,SFTPD,VPS54,TSPO2,MYLIP,G6PD,TRAF6,NDP,SLC12A2,DMPK,LAMTOR1,CD2AP,TMEM203,PLN |
| 4.891e-08 | -16.83 | Regulation of activated PAK-2p34 by proteasome mediated degradation | REACTOME pathways | R-HSA-211733 | 51 | 35 | 10285 | 3229 |
PSMD3,PSMB7,PSMB1,PSMB5,PSMA3,PSMD12,PSMC4,PSMC1,PSMA4,PSMB11,PSMC5,PSMB10,PSMA5,PSMD1,PSMB2,PSMB6,PSMA2,PSMB3,PSMA6,PSME2,PSMD10,PSMD6,PAK2,PSME1,PSMB4,PSMB9,SEM1,PSMD7,PSMD14,PSMC3,PSMA1,UBA52,RPS27A,PSMD4,UBB |
| 4.965e-08 | -16.82 | pancreas | COSMIC cancer mutations | pancreas | 16441 | 4769 | 16828 | 4835 |
CYB561D2,GMPPA,PXMP2,ATP1A2,MT2A,PPP1R16A,DDX42,SLC7A14,BNIP3L,CXCL14,ADAMTS1,CLDN8,RPL6,SPRR1B,TUSC3,GLIPR1,SQSTM1,RPP25,RBM12,RAN,TMEM177,FMO2,CREB1,SERPINA5,BICD2,KIAA0408,NAPG,RNF122,KCNH1,DLG4,GTF2F2,OR2H2,PAFAH1B2,CCL17,KIAA1191,CDH13,NPY5R,HSPA14,CXCR4,LCN9,BRD9,PGR,HAND2,POLR3B,TMEM106C,NUS1,SRP14,MANSC1,GJB2,WDR3,KRT7,PLEKHA8,ZNF609,TMCC2,SELENOS,KCNK10,SLCO1A2,TMEM164,SYNJ2BP,ACP6,APLN,TAS2R5,PTRH2,FOXS1,CRYBB3,OR4F6,ACTR2,KLHL15,RFXANK,PAPOLB,PLAGL1,SESN2,TRAM1L1,TRAM2,PPP1CB,EHD1,MPV17,FCHO2,CHST1,ZNF576,ISCA2,RABL3,UPF3B,GCA,CRYGD,RAB33A,FAM107A,RNF167,PPDPF,TNFSF18,DNAJC8,UTP23,GIMAP2,GNPNAT1,FERMT2,EIF3J,TOMM40L,RNASEL,CHI3L1,SPTBN1,TNRC6C,IFNG,JUN,TMEM50B,CD47,HIRA,S100A8,CBLN4,RHOJ,WWP1,RAB23,CMAS,SFT2D2,PTGER1,SUMO3,OPHN1,ZNF687,OGG1,CCR3,PPID,YPEL5,ABRACL,CAPZA2,RB1CC1,SLC35E1,RFTN2,TPPP,CCL8,NAA60,PLA2G15,STX6,FANCG,OR2A25,MAPK1IP1L,HNRNPA2B1,TAPBP,ATP6V1C1,RCBTB1,GGCT,LHFPL2,SCD5,MAFG,ACAP2,NFKB1,PRKAG1,HNRNPK,PAFAH1B3,OAT,MRPS28,RIOK2,OS9,RPL26,POMP,DYRK2,FOS,EGLN3,CLDN22,STAT6,SNX24,ACADSB,ISG15,OR10G7,DYRK1B,WIF1,FN3KRP,PHYHIP,RAB9B,AMT,INPP4A,KCNIP3,FGFBP2,ARCN1,EZH2,B4GALT3,ZFP1,PDYN,CRBN,SACM1L,VPS33A,CD226,WDR44,GPIHBP1,CTNNA1,RAB2A,CCNF,VAMP2,TRAPPC6B,SNRPA,CMPK1,BEND5,AP1AR,SMN1,WEE2,PCDH19,RAB5C,PNP,SELENOK,STK38,TIMM10,CAV2,C1QL1,FBXO25,PSRC1,IFI35,CSTF2T,RAB37,SLC6A11,FOLR1,IL6ST,TMEM59,LYNX1,RPL23A,PLEKHJ1,MLF2,ELMOD1,TXNL1,DERL2,TIMP1,SMAD3,SLC25A4,MRTO4,PTHLH,PPP2R1A,EIF4B,SELENOV,LDHAL6B,CCDC65,TDRD7,CD2BP2,HMBS,RBMX2,NDE1,AMY2B,ZBTB45,ABHD13,HRH3,RAB1B,INHA,OR5L1,RGS5,RPAP2,ACTL6B,FAM168A,SNIP1,SLC4A8,LY6G5C,UBE2D1,PGM2L1,ROGDI,SLC23A2,GYS1,AKIP1,SOS2,PIWIL2,PPFIA3,OTUD7B,MED11,CLIC2,SDHAF2,ELSPBP1,STX18,ORAI3,SLITRK2,CDKN1A,GK2,RBFOX2,FOXN2,CDH8,CPSF2,OR14J1,TRIQK,GPX5,PCGF3,GDE1,TCEAL7,TMEM14A,UQCR11,GLT8D1,NGB,MOV10,TAF5L,MYEF2,PNPLA8,TOP3B,TEX12,B3GNT2,HIGD2A,TMEM91,CASP12,ZCCHC9,SLC43A2,CAB39,LIX1,KLK5,DDX4,MRGPRX2,GRIA2,LRRC24,LRP6,PYROXD2,MRPS21,LCA5,STK24,NDUFB4,RAC2,CEP97,ZNF501,POR,ST3GAL5,SLC32A1,PARP11,CSNK1A1L,SOX2,ST3GAL1,IL18,DERL1,PRKAB1,UQCRH,DPEP1,MTHFD2L,CD36,IRF3,STXBP1,PAX9,KLC2,PCMTD2,STOX2,ERV3-1,TSN,STOML3,STAU1,KLK6,FKTN,DNAJC3,RNASEH1,TMED7,SLC41A3,SERINC3,STMN2,RGS2,DUSP19,NME1,ADPRH,PDHA1,NOS1AP,BCL10,KCNMA1,MBD5,ABHD4,PCDHB1,BRCA1,TRAF2,RBM7,KCNK13,CDK4,NPR2,DPY30,CNNM4,NR1I2,PROS1,GPX3,TMEM204,EWSR1,B9D2,ACSL4,TGFB3,MRFAP1L1,TRIM24,DTYMK,CIB2,YAF2,ELP3,MTRF1,ZNF592,EED,MRPS16,ABHD14B,CCDC25,TES,LMNB1,BECN1,GMPPB,CALHM2,ADO,VMP1,CBR4,SLC19A2,MSMP,HSPA8,EMP3,CHMP2A,OSTM1,COMMD8,ITGA6,CSNK1A1,PELP1,IFNA10,MT1M,DEFB114,TFE3,SH3GLB1,THTPA,PREPL,RNF113A,EFNB1,GOLGA7B,TSPO2,OLFML3,RPLP0,IL10,UBE2V2,FUT9,PHYH,HOXD12,ADIG,NTN4,RTKN,FABP7,BCAP29,ZBTB17,B3GALNT1,CREB3L4,EIF3K,CD274,KHDC1,NAT2,SPECC1L,BZW2,OR10G9,TSPAN5,RINT1,EIF4E,TRIM5,TMSB4X,COX4I2,CDKN2C,LHFPL4,BLOC1S2,SNCG,SNAPC3,DDX39A,RAB40AL,IGBP1,AKAP12,SSU72,TMSB10,IPO8,CIDEB,ATAT1,ARMC7,TMEM123,DSTYK,ZBTB5,AIF1L,ZC3H7A,CCR2,FCN2,RER1,SFRP4,RGS7BP,CDKN2AIP,CSRNP1,SYP,ATG4A,ZNF862,MRPS23,FUNDC2,HSP90AB1,POLE4,GPHN,ISG20L2,BCL7B,TOM1,GPR65,TEX30,SEC61B,GBE1,CHGA,TCF23,PAPSS2,TMX3,HTR5A,DNAJC22,EIF2B3,SRRM5,TOP1,TMEM144,NRSN2,GPR137,APOO,BCS1L,SNX17,MYO6,ZNF740,NDUFS8,CYP2C18,NKX3-1,F9,PGPEP1,GCNT3,OPRK1,ACAT1,TMEM114,ZNF287,KDM4B,TMEM184B,LAMB2,SLC13A5,CLDN4,RAB3D,CXCL3,GTF2B,RUVBL1,SDF2L1,GIT2,NKIRAS1,OAS1,HTR1F,OR4Q3,RDH10,PDCD4,LDOC1,GPAM,PRPF19,CREBBP,GREM2,TGIF2,GPX6,POPDC2,CDC42SE2,ACBD7,FAM98A,RPLP2,TRIM54,UHMK1,CRTAP,LCP2,ERH,ALKBH5,ADIPOQ,ANKRA2,FAM162A,CTDSP1,CCNB1,CRYBB2,AKAP14,NDUFAF4,TFCP2,CLDN1,ABHD6,METTL2A,CSGALNACT1,R3HCC1,SAT1,RMI2,COL1A2,SLC35D1,SMU1,GTF2H2,MAP3K11,MBL2,JPH4,AMIGO1,PTS,TOR2A,METTL14,VAMP5,GNG2,EDEM1,RAB11A,PPIL4,CCNI,ASMT,CDO1,CRABP2,PRRC2A,DPP10,SF3B4,IL20RB,DKK3,COMTD1,FNDC8,DLX1,AKT1,APEH,FGD2,L1CAM,SNX20,FIBIN,WDR38,TLR9,EHBP1,MGP,MDM2,MRPL13,GSTO1,TMEM156,SPRN,PSMA3,CCDC69,GALNT1,SOCS5,AK2,CNP,RND3,B9D1,NUDT3,LYAR,PFDN5,EXOC8,UST,GNRHR2,TOM1L2,CD99L2,PRIM2,SNRNP27,UBR7,SDR42E1,PDIA6,TRIM32,RNF141,KLHDC8B,PLA2G5,KLK9,ARHGAP1,DOK4,GDI2,MRPL23,GFM2,E2F6,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,POLR3H,TRIM3,C1QC,TMUB1,EDF1,ATP6V0B,TMEM219,ZNF207,MEAF6,UGCG,RPS14,LIG3,LYPLA1,ZNF671,SLC25A31,SLC17A5,ATPAF2,KIAA0232,CLU,LMO4,CNIH4,GLUL,CDK5R1,NCKAP1,NRP1,APOBEC3A,ZNF397,ID4,SEC14L1,ZNF319,XAGE5,TAAR1,SLAMF9,ZMYND19,CCR6,OR8B8,IRF1,P2RY1,STRBP,ING1,NHP2,TRIM23,NAIF1,ARMCX1,UBE2A,CCT2,CHRM4,UBE2D3,ATP6V0E1,GABARAP,FGFR1OP2,TCP11L2,GRPEL1,ELMO1,PRPSAP1,LTBR,CASK,GAL3ST1,OR4D11,ZNF304,MRPL24,MRPL50,SLC30A5,KLK3,SNAPIN,RAG1,ENY2,DHRS4,SLC35A1,IMMP2L,MEF2A,RMND1,MIOS,PPP1R2,FAM78A,IL15RA,OSM,SLC38A9,TLR3,GPAA1,ADGB,JAKMIP1,SENP5,CYP11B1,GRM2,CTNNBL1,IDH3B,CHDH,GNRH2,LRRC69,SWAP70,HSD11B1,CYP39A1,MYL12A,EIF4H,ITK,NCR3,FAM8A1,MLF1,GTF2E2,CCL19,TBC1D10C,NKX3-2,MAGOH,JAK1,LBH,AZGP1,HBE1,INO80C,ABCB1,FGF1,AZIN1,PSME2,SMAP2,CDCA3,RAB3B,KTI12,NDST1,DNAL1,DHRS3,TNFAIP8L2,DEFB116,MFSD6L,LYG2,AAMP,TMEM213,MX2,GPBP1L1,ZCCHC10,SYN3,WDR77,MTPN,FZD4,MEST,ATP6V1G1,TSEN54,SERPINB10,TMEM215,FBXO42,ZNF24,MMP9,BTF3,CYP27A1,S100A6,DYNC1I2,LHX2,ZYX,UBAP1,CDC73,DNAJC5,TMIGD1,PACSIN3,SLC7A9,HEBP1,ALKBH4,SNAP91,MYH2,VRK1,ROPN1B,PGK1,ATF4,CTNNBIP1,GNG7,GSTO2,KBTBD2,RARRES2,GRSF1,KPNA1,PIWIL4,CSNK2A1,KIT,RS1,AFTPH,OR4D9,LSM3,SUPT7L,JOSD1,P4HA2,AGK,ANAPC2,FBXO32,MCOLN1,PSMB5,ENPP4,CCT5,SLC39A7,SORD,SBK2,CD58,AGER,IMPACT,RAB18,FKBP14,IDH2,ARMCX5,ZNF593,PRPF4,TTC4,SCFD1,CCDC47,CACNB4,TUBG1,RPL15,GHITM,TACR3,CIB3,PRMT2,CAMK2G,BUD31,SRP54,TMX4,CCDC127,FAM89B,PEX3,RCVRN,PPP3CA,CRYGB,KCNJ11,CD200R1,FGFR1,HCRT,CAMK2N1,SHC1,PYGM,OR4K1,HEY2,PCDHB8,RBM17,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,RNASET2,SLC35E3,SPTAN1,NPY2R,LRP12,PAEP,NIPA2,RABL2B,CLDN11,FAM199X,TRAPPC1,RMND5B,PGS1,RBBP7,SLC25A21,ZBTB38,HECW1,TRIM37,NFIL3,SETD5,HNRNPC,PTPN1,SPR,PPARG,GALNT12,ARFIP1,ACTA2,TRIM21,SIX5,ARMCX2,SURF4,INTS10,XPO5,CREB3,RNF103,TF,GJA10,SLC25A32,EFHC1,KIAA0040,EEF2,THRAP3,XPO1,EXOC2,ZMYND11,TXNRD3,ZNF513,SLC7A4,RNF187,GPR162,APOBEC3C,GSK3A,PRCC,UBXN10,PFDN6,LDHA,NUBP2,PCDHA5,SLC20A2,FATE1,ATP2C1,DNAL4,RC3H2,NUDT19,RANGRF,ABCC5,THOC1,GLE1,TXNIP,CREBL2,AQP4,GNMT,CCL25,PSMD6,IL23A,SLC39A9,DHX9,FURIN,OR51S1,ZSCAN1,WDR37,EIF4EBP3,CXXC5,OSR2,CIRBP,ANKIB1,ENDOD1,SH3GLB2,EIF2B5,GALE,FUT8,GTF2A1,WBP2,NEK7,UTS2R,MOB3C,LASP1,PHKG1,SPOCK1,SERPINH1,RPL37A,CLDN14,ZKSCAN1,HSPE1,PGBD2,STAMBPL1,SIPA1L1,GXYLT1,OR6M1,NUDT16,LHFPL1,B4GALT6,KCNA2,HSPB1,LEAP2,HADHA,SOX21,RAB4A,TRA2B,DHX16,WNT7A,LEPR,STX17,ISYNA1,NDUFB8,APH1A,EIF1AD,NAA11,FRA10AC1,PDIA3,XPOT,CXCL1,CDC37L1,SNAI3,PELI3,NLE1,KRR1,MSX2,RPRML,KCND2,NDUFA5,CCL21,PTCRA,TRMT6,FGF17,HBB,NEDD8,CXCR1,RABAC1,WWP2,RAP1A,UCKL1,ACAA2,CD2,POLR2I,FBXO30,TIGD7,RASGRP2,LPXN,ST13,IL34,DFFA,TBCE,SPATA2L,IPP,NQO1,LMBR1L,AKR1C2,NPVF,IGFBP4,TAC1,OPA3,KIF1C,CHRNA7,GAS8,CDKL2,BRMS1,PAOX,CD3G,TMED1,RBM23,BRI3,OCEL1,ADAT1,HEXA,OXNAD1,TSSC4,ALDH1L1,MAK16,NONO,POLL,SPRED1,H19,SIVA1,GFOD1,EMC4,GPR37L1,NDUFAF2,SNTA1,SNAPC1,SV2B,HPCA,ZNF805,TCP11L1,SOST,EIF4EBP2,OR2A2,MMACHC,TRAF7,DUOXA2,MTMR12,ABHD16B,RAP2B,ZBTB42,TNFAIP3,TAPBPL,ETV6,RRAGA,SIRT7,IQSEC1,NOL4,FYTTD1,SNRPD2,FAM13B,ADCY3,DCAF5,ESR2,CDK6,CWF19L1,CTNNB1,RAB8B,SOCS2,INTS12,CYP2D6,SFTPD,CLEC12B,OAZ2,VPS4A,NAB1,ENPEP,RTP4,ZMAT5,LSM6,SYNGR1,PROX1,PRKX,FGF13,ZNF174,USP38,USP39,CERK,SLPI,WFDC13,ACOT13,TMED3,RPGRIP1L,OR2W1,CCND1,FBXO9,COX7A1,LCN6,OTUD6B,SETD4,BMPR1A,FAF2,ARHGAP21,SCG2,RHCG,SPINK13,MRPL47,S100PBP,TMEM33,MPHOSPH10,AP3S2,KLF10,S100A10,FAM200A,NFYA,DUSP1,TGFB1I1,TOLLIP,BATF,STX8,RAB3C,MTAP,PWP2,CETN3,URM1,CTSK,CACYBP,AP1G2,NDNF,DCAF8L2,ANP32B,CPT2,CHST9,BPGM,CDKN3,PPIB,CD164,SPEF1,NUP107,OR52M1,SCAMP2,NLGN2,DEK,SLC5A6,CYP4F8,PRKD3,CTSD,PGAP2,MRGPRX4,FABP5,NFE2L1,AKR1A1,SPATS2L,NOP58,MRPS25,RBCK1,KIF2A,MIA2,BACH1,ING5,INPPL1,DEGS1,CRYBA2,POU1F1,CYC1,CCDC42,FCAR,NPTN,ARMC8,SLC35A2,ENTPD4,PTDSS1,ID1,SLC25A46,HSD17B1,HEXIM2,TMED4,TBC1D17,IRF8,RWDD4,KPNA6,PTRHD1,TOX,FCER1G,BET1,CYB561,SYNDIG1,GSTM3,TSEN34,FTSJ3,GADD45B,STX7,SENP8,MGST2,OSGIN2,LIMS2,NECAP1,MZT2B,GPC4,HBA1,PKIA,TRAFD1,TRIM35,PPM1B,TP53,INMT,NFKBIL1,CRELD1,TAX1BP1,KRTAP3-1,AP2M1,PRDX6,KIN,GABPB1,ARF4,SCGB1C1,RDH12,TAX1BP3,ZNF790,CALY,PML,GABARAPL2,PSMA4,DNASE1L1,SERTAD3,ZNF250,OR10A7,EIF1B,MT3,DUSP6,MTHFS,SETD7,PPIF,DAG1,ZBED3,CYB5D2,RPS12,TXN,MAF1,DCAF4L2,RPRD1B,LYPLA2,SNRPN,TSPO,POP7,STYK1,RNF181,CELA3B,OMG,GPD2,CYP11B2,FBXL7,LBR,PHF21A,RHBDL3,TRMT61A,CAMP,COX5A,THNSL1,SLC1A2,ENO1,OLFM2,GNPTG,CRYL1,SERPIND1,CHST7,ORAI2,RPL24,TFPT,ALOX5AP,ELOVL6,PRDX4,SLC25A14,NUP35,MECP2,ZNHIT1,CLSTN3,TBC1D19,RASL11A,RGS6,CSTA,NAA15,SYBU,EXOC5,SERPINB6,EBLN2,FTHL17,RALA,WDR55,G6PD,ADK,F11R,PPP2R5A,TLR7,GAPT,VASH1,PTGES,ACADS,RNF128,CAPG,OGDHL,TLR1,SAR1B,CCR5,RHAG,IL12A,BRMS1L,OR5B3,PAPOLA,DHRS1,HCST,FBXO34,ZBTB16,ANAPC16,CHORDC1,TMEM42,SNX33,NDP,SDCBP,MED23,USP13,FGF3,DRG1,ERLEC1,CEP85,SRPRB,POLR2D,SNX12,CNTFR,KRT222,NEURL2,PDP2,SMNDC1,CLEC7A,APPBP2,KCTD11,GPR146,OPTN,ARPC2,GINS3,MYL12B,ENHO,IL7,ATP6V1E2,ZHX3,PID1,NECAP2,SRSF4,SH3BGRL,EXOSC3,ATXN1L,LRRC20,EGR2,HAX1,OR1F1,RPS3,TMEM60,CHN2,CALU,AIF1,HBEGF,FOXJ3,ORMDL3,USP30,UFM1,RAD23B,LGALS3,NMBR,HHIP,LUC7L3,MAP4,SMYD3,DDIT4,RAB3A,CTNND1,KPNA2,FAM91A1,LCN12,OR10Q1,KBTBD13,YIF1A,CA8,OR1S1,SH2D5,HMGA1,FOXI3,UTP6,GGPS1,TSPAN11,MND1,IPCEF1,AUH,ZNF267,IDE,TFRC,TTC8,HSD17B11,PPME1,ZNF177,ZNF652,C1QTNF1,CD83,DNAJC7,KCTD12,UQCRQ,RPL12,GFOD2,ADAMTS20,SOD3,DUSP22,ICAM1,MTMR2,PLCL1,YWHAH,MRPL49,FAM187B,GABRB3,PABPC1L,LSM2,CCT8,TMBIM6,C1D,ZNF22,TFDP2,ACTR3B,MIF,ZNF189,EEF1B2,RBM15B,HRH2,AP2A1,APTX,ZNF688,RGMB,SPINT2,TMEM45B,BCL2A1,FBXO11,SPSB1,RBBP9,WNT10B,HMX1,DGCR6L,VIP,ETFB,LRRC8D,NTNG2,TMEM108,SURF6,BRD3,FAR2,TESK1,DVL2,OR2AT4,C2CD4C,TTC33,RPL39,WRAP53,MMD,MAP3K21,KLHL26,BET1L,UCHL3,EEF1A1,TRAPPC4,GAS2,TFPI,PAAF1,PRKCA,CLIC4,NPTX1,COX11,HNRNPH2,HMOX2,ADM2,ALDH1A3,AHCYL1,IZUMO4,KCNJ8,SAMM50,ENC1,TRIM6,PYGB,FOXP1,SLC4A10,HOMER1,PSMB9,PDE8A,RCCD1,EXTL2,SLC20A1,ALPL,LAP3,ADIPOR2,EFHD1,C2CD2,RPL9,TST,RNF5,DGCR8,LRRTM2,API5,TPH2,PHACTR1,CRYM,SAMHD1,SPRYD4,KCNS1,DNAJC30,P2RY12,FKBP1A,SRXN1,ZMAT2,NT5C2,DOLK,EHD3,ST3GAL4,MRPS18B,AKT3,POLD4,MAN1A2,ERVFRD-1,CCDC92,EIF3D,DNAJC4,RBP5,CHMP2B,ELOVL4,PAK6,GRB10,PIGY,CSNK1E,SKA1,ABCB9,FAS,ATF1,COX6A2,POLR3GL,MAD2L2,TMPO,UBTD1,RBBP4,OR5A2,ARMCX3,CPLX1,COX16,CUL3,SDC2,FAH,CAMSAP2,ACVR1B,CTDSP2,RPL10A,RAD21,AKAP17A,RAP1B,TXNRD2,DNAJB4,C2C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,TSHR,SLC25A20,EIF2D,NEUROD6,AIG1,INSM2,RAB31,STC1,OR8K1,DYRK1A,DRP2,SRGN,KLHL32,G0S2,OR5I1,TAS2R46,TRA2A,SATB1,BEND6,PRMT5,ACO1,GANC,CACUL1,RALGAPA2,PPTC7,PCK2,SFXN1,UBAC2,KCNF1,UBXN6,NME2,CD4,NR4A2,SLC25A45,NOSIP,DTD1,REXO2,POC1B,NTF4,GPHA2,CYB5R1,LRTM2,MYT1L,USP2,SLC39A13,CYP4F12,CPE,DCAF4,PCSK2,ARHGEF6,SCN1B,CDC40,NELL2,NDUFB5,TM2D2,SUB1,OR52W1,NOVA1,INPP5K,MCAT,NUDCD3,SEC63,IRF2,TM4SF1,PTTG1,ERP29,BCCIP,WFDC5,CAMK1,NOL7,SNX2,TACO1,NSA2,SSBP3,NXPH3,DEFB115,ASRGL1,POU3F4,MFSD6,MADCAM1,MPST,PSMC4,IDH3A,PATE4,RFC5,JRKL,TMEM97,NSDHL,MED13L,SLC35C1,NXT1,CHMP1A,RLN3,ANKRD50,NEO1,ESAM,PCCB,HSD17B3,GAPDH,CBLN3,CRYGA,VAC14,CLIP3,SLC25A42,YES1,RNF208,GRIA1,PI15,HECTD3,HDAC5,FABP12,FGL2,UBL4A,SERPINB11,RPL17,GKAP1,AGAP2,GUK1,STX1A,FBXO3,IRF2BP1,ACHE,UBE2B,CSE1L,OR4N2,FAM3A,STAC3,MNAT1,NEK9,FMO3,TNFSF10,CDK5RAP3,CLDN6,CAPZA1,PDIA2,SAP30L,RNF146,SNAP23,FAM76B,BOLA1,ELOF1,GGCX,PAQR4,CCAR1,PICK1,NTRK3,TSSK1B,IFT52,PIK3R1,ACOX1,F7,FADS2,TSPAN7,KDM2A,KLHDC8A,POLD2,ZNF574,EXOSC8,SUMO1,DCLRE1C,G3BP2,OR10G3,OR2J3,SRSF1,ITGA2,DIO3,SLC31A1,COX6B1,LMBRD1,UCK2,FGF7,MAPRE2,CAV3,EPHA2,PRPF18,CDK2AP2,IGSF21,RAB28,COX17,DDI1,CYP1B1,MDH1,ELK1,FAM168B,RALYL,MRAS,MRPL41,MRPS35,ATP6V1G2,MMP14,RAB6B,LHB,INSIG2,DEFB124,CBL,HSDL1,KLHL23,WDR6,ACOT6,IL12B,ANGPT1,NCALD,COPS4,KCNK17,ZGLP1,USP46,SMAD2,PITPNB,POLR2C,GNAQ,LPAR6,CCDC167,NGRN,DBNDD1,RAD1,GIPC3,NFE2L2,NCOA5,RUVBL2,IGF2BP1,GOSR1,PPIC,MMAA,SIKE1,NDN,ARMC6,CHCHD1,SNX3,TBC1D5,DBH,CLRN1,LGI1,CDC5L,TMEM19,SLC35A5,HPS6,OR2F1,CH25H,CRMP1,TCP1,KCNH8,CNOT7,RABIF,ADRM1,CD80,NMRK1,TAF11,PKIB,EMX1,HNRNPL,IREB2,UBTD2,P2RY10,NKX6-2,PLAC9,SLC38A2,HS3ST5,GPR22,LIN7C,SSR3,PFDN1,TAF2,SGMS2,NCSTN,ANXA7,PRR19,UBE2N,ANO3,CCL1,NGDN,CTRB2,FKBP4,STX16,PSKH1,DPPA2,PMP2,EIF5A2,PI3,SMURF1,CTTNBP2NL,VDR,IL5,PTGDS,TNNI1,PEBP1,ADRA1A,PSMB2,FGF22,CX3CL1,COL3A1,CBX7,PAK1IP1,GLYATL3,VAMP1,ADRB2,MYO1B,QSER1,SLC2A1,SRSF12,GPT,TLR4,GPN2,SLC6A1,B2M,SASH3,TPRA1,TIFA,CASP4,SLC15A2,SLC52A3,TRIM22,CYB5R4,SPOP,DEFB129,MRPL36,AMACR,NR0B1,FITM2,ITM2A,DCK,ADH1A,EAF2,DCUN1D1,RPS24,MCM6,NUDT4,CYP7A1,SDS,DIRAS1,PRRT1,ABCE1,GINS4,PAQR8,PPP1CC,OR7D4,PEX26,BAZ1B,OR4E2,ZNF32,NOP16,KCNB1,TNFRSF9,LRRC8C,DMAP1,CST3,PLEKHO2,LYZL4,BCL2L1,YWHAG,ICA1,VDAC2,DCTN6,ACVR1,MYH1,IFT57,KLHL28,EDEM3,TPPP2,EGLN2,LRRTM1,RNF152,MRPL33,UQCRC2,CXCL9,RBPJ,MRPL17,DUSP9,CFDP1,ATP2B4,SIGMAR1,IFNK,ACTN4,GATAD1,RGS10,PTGES3,ASB1,RPS15,FBXL3,QRSL1,VIPR1,HSP90B1,TCOF1,LRAT,RETN,NKRF,MCPH1,EDDM3B,ISOC1,ZDHHC8,METTL18,RSBN1L,GAD2,SEC61A1,TTR,ASB11,RGS1,SDHC,NOL12,RHOG,FAM83A,CDC42SE1,COX7B,BGLAP,CXCL10,FBLN5,LYRM2,FOXD3,MAEA,ZNF345,EID2,KIAA1958,TPD52L1,ZNF770,RPS28,UBXN2B,DUSP18,SVIP,SMUG1,SLC37A4,CDH7,ASCC1,HNMT,ERRFI1,FA2H,SERTAD1,KCNIP2,ZHX1,GPR83,LPCAT3,ZCCHC7,PHTF2,PPIL3,DPAGT1,CTSA,ZBTB26,LRRC14,PDCD5,PRDX3,EMILIN1,BTBD10,ZMYM6,EIF2B2,ARF1,GNG11,HMGB1,PHF7,MRPS26,THAP6,CKB,TUBA1B,LSM12,FIG4,CXXC1,RPL7A,DCTN4,SEC22A,MAP2K3,DOK5,ZDHHC24,B3GALT2,PPT1,ARF6,MRPL12,FGR,FAM20C,SPHK2,RCHY1,UBE3A,OR5K1,PDZK1IP1,PDE6D,OR4B1,LRFN3,S100B,TNIK,RIT2,CACNG3,ZC4H2,TADA1,CETN2,CBFB,ZC3H14,EFNA5,ASPM,SH3BP4,LEP,SMARCE1,PITHD1,PLEKHF2,SNRNP70,SERINC1,GLIPR2,MID1IP1,TDP1,SPCS1,RPL19,IL21,SLITRK5,RNASE4,DDIT4L,SAP30,HBM,FGF16,MSN,POU5F1,ZNF362,SLC6A7,MAGEB1,DICER1,EZH1,ARGLU1,TECR,MRPL16,RNF7,MAP3K3,KRTAP4-1,ARL11,FHIT,MED29,UBE2I,TMEM106B,UCP2,MXD1,MFAP1,SLC41A1,LAMTOR2,PNRC1,PLP2,ABCF1,DUS4L,NUP62,SMG5,RNF139,DYNLL1,LYPLAL1,HSDL2,OPRL1,CCND3,ARL6,RAB11B,STX5,LEMD3,CSRP1,IRF4,TBC1D16,SLC7A1,CA12,SPATA4,CMTM7,ADRB3,FMOD,IFNAR1,SDR16C5,SLA2,MARCKSL1,CCL11,RPAP3,RXFP2,RAB9A,HINT1,THOC6,PYCR1,TNPO2,WBP1L,OAZ3,VCPIP1,TCEA1,HM13,BCAS4,SLC39A10,MCCD1,MB21D2,LCN15,PGAP3,RNF182,RELL1,TIMM17A,SMAD9,UFSP1,PTPN5,LIPA,CCL24,SNRPD1,JUNB,ALCAM,PREP,SHC3,CDC26,STK38L,MVD,PIGC,ARFGAP1,CYP4F22,RPL28,HCFC1R1,CACNB2,FIS1,EDEM2,SLITRK1,DDIT3,SRP72,LSM5,DCTN3,PRKCB,IRF2BPL,PABPC5,HCFC2,RWDD1,SLC25A3,RBM41,COPE,CKS1B,DYNLRB2,HBP1,RPL4,SEC14L5,RGL1,SUV39H1,TTLL10,ATG16L1,SIGLEC5,HDAC11,DIRAS3,TP53TG5,TPST1,ZNF200,IZUMO2,HNRNPH3,LCP1,AGGF1,PCYT1B,CSF2,KRT8,PRELP,GJB1,GCHFR,CHCHD2,SKP1,CLP1,CLPX,OR5AN1,ATG3,INA,CFTR,MYLIP,SUPT4H1,FAM174A,VPS39,PTPRZ1,IFI16,SART3,PSMB10,CHMP1B,CDK17,TMEM39A,ART5,ATP6V1D,CDKN2D,GPR37,ESD,VWF,MLH3,PCBP4,FAM193B,APOBEC3B,BLVRA,CRYZ,FOXC2,PITPNA,RAB32,CRYBA4,BARX2,PSMD1,MPP1,ADH1B,SRM,RANBP10,MED27,BMPR1B,OR4M1,SPDYE4,TULP3,HS3ST1,WDR12,IAH1,KLF12,MLN,MAP1B,ZDHHC17,VSTM2L,FBXO31,PIGK,PELI1,CNOT8,NEU1,AMELX,VSTM4,GLO1,RAB1A,PDCD1LG2,TEF,ANKRD10,SCN2B,ADD2,SOD2,PCP2,TCTA,TMEM231,MMP20,GTF3C4,DNM2,OR4K13,TSPYL4,C1QL2,PLCXD3,REG1A,CLRN2,SRD5A3,DCAF16,ALG5,DEXI,SDHAF1,STARD5,FMO1,ABCC2,SUGP1,ACTR1B,STAP1,SMARCB1,HTR2A,CD59,ECD,PRELID1,ETFA,RIMKLB,AQP3,PSMG4,HS3ST3A1,TICAM1,TLR5,HIGD1C,LCN1,RFC4,PNPO,OR2D3,COTL1,GPM6A,CHST10,KCNG3,SOX9,APEX1,PRSS1,PSMC5,JMJD8,ITPRIPL2,GAB1,AKT2,BCKDK,TRMT5,OR9I1,CYB5B,ZCRB1,MED4,NAP1L5,SEMA7A,MRGPRX1,HPCAL1,LIPT2,GABBR1,ERCC3,THG1L,PDLIM4,RPF2,XBP1,TIMM13,TBC1D1,GPR34,CHRM5,NACC2,CEACAM5,NAP1L3,DRD3,MTA3,EMILIN3,CA14,DIS3L,TACR1,ARHGAP19,CEP57L1,OSBPL8,ACTL6A,ACP2,GNPAT,NDUFAF6,FOSL2,TMEM126A,SETD3,GPR75,SYPL1,CHTOP,ZNF343,STARD7,EGR1,ZNF436,WBP11,MAGEA4,STT3A,RBM3,CCDC126,RRP7A,CORO1C,RACGAP1,ARHGAP15,RHOH,HYAL2,UBE2S,ERLIN2,NPBWR1,PIK3CG,RPSA,DEFB1,IFRD1,ACSS2,MAP1LC3B,PDLIM3,PRSS37,CTLA4,RBM5,ATF3,RANBP1,TMEM176B,CEBPE,RPL22,B3GALT4,DLG3,RHOU,IMP4,HELT,PDE6A,SERPINB9,MT1X,UBE2V1,TIMMDC1,SNX11,RPLP1,MET,FZD6,RETSAT,POPDC3,SLC7A11,ADIPOR1,GAL3ST4,PRM1,GFM1,SEC61G,EMX2,CENPM,SSH3,HOXB8,CCDC22,NDFIP1,KDM1A,DTL,PSMG2,SNN,SNRPA1,ANKRD46,CEP70,ARL6IP5,ABHD2,CTDSPL2,GMNN,CYP26A1,TMEM87A,ISG20,RALB,NUDT1,UNC45A,FKBP2,PRSS35,TBCEL,EDC3,HAPLN2,SAP30BP,AANAT,ANKH,YKT6,VPS26B,CAMKV,ARL5B,F2,ESYT1,BIRC5,MFSD3,TRAPPC3,CSRNP3,NRGN,LDB1,WNT2,GMDS,BRS3,ZMAT3,TRAF1,RSL24D1,KCTD20,SERPINA3,RASSF4,CLK1,SKAP2,SEMA3C,DOK6,PSMB4,HERC3,DDX39B,CGRRF1,LSM4,IRF9,HSD17B8,CDR2,PTGER2,NETO1,NAA30,C9orf72,ZSWIM7,WTAP,RPL31,PDCD10,SSBP2,GDAP1L1,LRRN4CL,NOC4L,UQCRC1,AKR1E2,CRHR1,OLA1,PRPS1,HAS3,MGST3,TSPAN3,BAD,MEA1,TAF9,SCHIP1,HMGN4,CMBL,COX7B2,CDKN1B,OR6C4,MAT2A,NMRAL1,RFX5,TMEM198,TRAPPC2L,SCG5,PHOSPHO2,STRADB,LRP3,SIAH1,NCK1,TMEM168,USE1,ST8SIA4,TMEM220,CD200,ZNF655,TRIM62,TEX19,GPR78,HNRNPAB,ZBTB6,PLEKHF1,AHSA1,SLC15A1,KCTD16,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,OR4D5,TEX261,RNF10,POLE3,KRTAP8-1,GP9,OR51E2,SRI,NCAPG2,CNPY3,APLNR,CYP4V2,POLR1D,GPR160,DTWD2,PSMD3,TRIP4,RPL10,STAR,SUPT5H,PDCL,SPINK9,SLC25A24,GLCE,GK5,SSNA1,IP6K1,PTGFR,IL2RB,FBXW4,P2RY4,ST3GAL2,TAS2R7,CD209,RNASE9,GADD45G,YPEL4,PRSS8,LDB2,TMEM107,RPA2,CCDC90B,TRAF3IP3,PIWIL1,SRPK2,TAB2,CPXM1,THAP1,UNC79,CD34,FBXL4,PRCP,EID2B,TMEM100,DCTPP1,OR4A47,PLAC1,PSMD7,SCAND1,SIN3A,CDK7,RGN,CTTNBP2,RAB6A,FKBPL,ZNF428,PDE2A,TNFSF8,CDIPT,PYCR2,ARFGEF1,MED22,NOG,PMPCA,TLR8,CD40,AIP,TNFSF15,SLC6A2,CRY1,THOC3,MX1,BOLL,GLOD4,PIGA,VPS54,SLC25A27,RBMS2,TGFB2,ATG9A,ZNF622,S100A11,RUSC2,CD9,OR1M1,GADD45A,IGFBP3,GRPR,DPEP3,TMEM183A,BTG3,NPC2,TMEM115,NUPR1,PNPLA4,PIAS1,LRRC28,TCEA2,PARD6A,RNASEH2C,HSPD1,EIF1AX,SPG21,TIA1,SLC22A6,DDR1,TMEM81,SAP18,EXOC3,CAP2,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,GNA11,SERTAD2,HSPA5,HSPB6,THAP8,WDR45,MPV17L2,CRYBA1,NRM,TMEM229B,GNB3,HINFP,CMC1,NUFIP2,VAV2,CCDC3,ITGB8,BTG2,NR1I3,LRP10,PAIP2B,TRIM44,TRIM26,IER3,NUCKS1,CENPL,KLRC2,TOX4,CPNE2,TMBIM1,IFT172,CYTH4,RAMP3,FXN,UPRT,SUPT3H,MECR,SGIP1,MRPS17,FEM1B,MRPL9,UBE2G2,FAM151B,MACROD1,CYBRD1,ZNF518B,ADCK1,FAM136A,SLC35E4,SLC25A5,PRR13,WSB1,LYZ,TOPORS,OAZ1,FAM3C,PTP4A2,MFAP3L,SLU7,VEZT,IRF7,KLHL25,TMEM165,OR8B4,RPE,SULT1B1,LRRC8A,CNPY1,SSPN,GNGT2,HAUS2,OR5M9,RP9,GALC,ELFN2,LBX1,NKAP,RDH11,KCTD3,PIH1D1,BRAP,TANK,SYNGR3,MPG,DMPK,ELFN1,MBD3,CDC23,CCR7,IGF1,RXRG,SNAP25,THUMPD1,GORASP2,TTC9C,GMPS,PELO,IL18BP,RASL12,ANXA4,GALNT2,RRAGB,SNRPE,CMA1,DLGAP4,GRIK1,SCML1,TAPT1,TYMS,MED10,ZFAND6,NAA16,RPS20,RUNX1,SLC12A2,GJC1,ATP8A1,CIAO1,KIF3C,GHRL,VPS18,ZNF581,DUSP3,PDE7A,SUCLG2,SSBP4,RASSF8,KCTD17,CLEC6A,RBP2,TLCD1,AQP11,EDA2R,LCORL,FKBP1B,LMO2,PSEN1,MAGEC2,OR13A1,YTHDF2,FAM161A,ANKRD6,ARHGAP12,PFKFB2,EIF5B,SRFBP1,DIRAS2,ACER3,MREG,TRAM1,TADA3,FUNDC1,ECHDC1,AP1M1,UBA52,IMPA2,MDC1,TRAPPC6A,SP1,CCSER2,MTCH2,ITM2B,MGMT,GIN1,TKTL1,RPL18,TBCCD1,TRAF6,ROCK2,FUBP3,KCND3,VPS72,KRIT1,RPS10,SPRY1,CCDC106,ETNK2,CLDND1,PRNP,HSD17B10,CAND1,GABRA1,TMEM89,MIS12,DR1,CBX3,HS2ST1,GTPBP8,LYPD6,ELMO2,TRPC1,ASPA,BCL9,SSX2IP,SYNPR,BCL6,GSTCD,E4F1,TMED9,GTF2F1,DLST,SNX10,CA2,SGTA,USP6NL,MTDH,PET117,ZNF263,TPPP3,CNN3,CPT1B,RBM27,ZBTB39,ANKMY2,TMEM47,MAD2L1BP,LY96,AP1S2,ADORA3,APEX2,SF3B1,TAB1,AKR1B1,TMEM185A,PAIP2,NDUFS2,SNRNP40,FAM83B,IVNS1ABP,PIK3CA,ERVV-1,CDH11,PSMC3,JAKMIP2,GSTM4,CRTC2,NPM3,TSPAN15,TMEM38B,NUDT2,PSD2,PEBP4,GH1,BAX,ATP1A3,FEM1C,COCH,PICALM,LST1,COX6C,XAF1,PIK3AP1,RPIA,VTA1,COX6B2,TMEM170A,RNF133,PRKCE,ZNF451,GNRH1,WDSUB1,PRKRA,TSPAN17,DBR1,TAS2R13,UBE2E2,TRAPPC13,HGS,RHOBTB3,POLR2L,POLDIP3,FSTL1,MT1E,DPH3,ELK3,CRISP1,LRRC40,CD81,LZTFL1,SNRPB2,SUMO2,TFB1M,CCR4,CHRAC1,KLF3,TNF,GGH,NUDT9,CYGB,PPAT,IL17F,CARTPT,SESTD1,KLHL1,FOXA3,PARP2,NF2,ABHD12,BANF1,PHF13,RPL26L1,CGGBP1,IGSF11,CYP2C9,MRPS34,TRIM45,ATAD1,DUSP21,RBBP8,MGAT4A,SGMS1,SLC19A3,OLR1,FBXO8,NDST3,MPPED2,PRL,CDC7,IL2,SEC13,VMAC,TNFAIP8L1,NBN,AIPL1,PEX13,TBC1D25,TYROBP,NHEJ1,WDR11,SLC35B3,FHOD3,TIMP4,ACCS,XRCC5,SNRPG,ADTRP,WDR5B,ZDHHC4,CDC20,CYP3A43,SPEM1,PDE4B,CCIN,UBE2L3,TTPAL,PMAIP1,EIF3G,MEPCE,HUWE1,ABHD10,CPLX2,PRND,SREK1IP1,FTSJ1,CNTROB,AKR1C1,RAB39B,CSNK1G3,MRPS11,ICOS,NINJ1,BLCAP,ITGB5,RGL2,NDUFC2,TRIM34,YIPF3,LXN,TCEAL8,RPS2,CAV1,B4GALT4,NDUFA1,DDAH1,GPR35,HFE,ALG11,MCL1,FAM53C,GSTA2,TMEM127,HCAR1,RB1,TRIM29,CORO6,OIP5,DPH5,PNMA3,ZBED1,CTXN3,DCAF12L2,PLSCR1,PTP4A3,HSPB2,COMMD9,STK3,CBLN1,LILRA2,TNKS2,LY6H,NT5DC1,MRPS18C,TRIM36,JAK2,PROK1,PAQR3,CREBZF,SPP1,FAM149B1,FRZB,CHRM3,TSR2,ARL2BP,ING2,ZNHIT6,GPR17,GPC1,PLCB1,PRSS23,TXNDC17,CITED1,ARL4D,LIAS,NPY1R,GCLC,PSMD10,TNNI3K,CPLX3,CTU1,EPHA4,GXYLT2,KCNJ2,PSMB7,TNFAIP6,FBXW7,PLG,DMTF1,CDK12,DLK2,OR4K2,GRM1,PCGF6,TAF1D,SHPRH,KCNJ10,ADORA1,SPATA2,SLCO3A1,HOMER3,MAGEB10,CXCR3,SLC25A1,STAMBP,HNRNPF,CEND1,ZNF511,EHD4,FAM81A,TNR,OR6X1,TM4SF18,BOK,OR8H3,SLC8A1,LSM14A,CAPN2,STARD3NL,YWHAZ,ICAM2,ABHD8,RNF222,REEP4,AASDHPPT,CCNA2,TM4SF20,GJA1,MAGED2,SLC29A1,SURF2 |
| 4.972e-08 | -16.82 | Orc1 removal from chromatin | REACTOME pathways | R-HSA-68949 | 72 | 45 | 10285 | 3229 |
MCM8,CDKN1A,PSMC1,PSMD12,PSMD1,PSMB2,PSMA6,PSME2,ORC6,PSMB4,PSMD6,SEM1,PSMB9,FZR1,PSMC3,PSMA1,RPS27A,CCNA2,PSMD4,MCM3,PSMB7,PSMD3,PSMB1,PSMA3,PSMB5,ORC5,PSMC4,CDKN1B,PSMA4,MCM4,PSMA5,PSMB10,PSMC5,PSMB11,PSMB6,MCM6,PSMA2,PSMB3,PSMD10,PSME1,PSMD7,PSMD14,RB1,UBA52,UBB |
| 4.972e-08 | -16.82 | Switching of origins to a post-replicative state | REACTOME pathways | R-HSA-69052 | 72 | 45 | 10285 | 3229 |
PSMD7,PSMD10,PSME1,UBA52,UBB,RB1,PSMD14,PSMB5,PSMA3,ORC5,PSMC4,CDKN1B,PSMB7,PSMD3,PSMB1,PSMA2,PSMB6,MCM6,PSMB3,MCM4,PSMA4,PSMA5,PSMB10,PSMC5,PSMB11,SEM1,FZR1,PSMB9,PSME2,ORC6,PSMB4,PSMD6,RPS27A,CCNA2,PSMD4,MCM3,PSMC3,PSMA1,PSMC1,PSMD12,MCM8,CDKN1A,PSMB2,PSMD1,PSMA6 |
| 4.975e-08 | -16.82 | ZNF574 (zinc finger protein 574) | protein interactions | 64763 | 242 | 107 | 19454 | 5460 |
SRSF4,MRPS17,RPL31,FGF3,PPAN,SRSF7,SKA3,ZNF526,SART3,RAF1,ANAPC13,TRAF2,RPS10,CHMP2A,WDR6,SRSF1,MRPL18,ZCCHC9,VPS4A,MRPS26,IFI16,DDX50,MRPS35,NGDN,DDRGK1,TRA2B,MRPL57,STAU1,MRPS7,NGRN,APOBEC3C,MFAP1,NOTCH2,PAFAH1B1,MRPL23,TUBB,RPL35,RPL7L1,PSMB6,RPL10,ESR2,KBTBD6,RPL19,ERH,PELO,MRPL13,MRPS25,ZCRB1,FTSJ3,NOA1,MCAT,RIT1,H1-1,NSA2,CUL3,ZNF668,MRPS33,NOC4L,IMP4,MRPS18C,RPL17,SNIP1,MRPL52,RPL3,LLPH,RPSA,APOBEC3D,H2AX,RPS16,SPPL3,MRPL24,SURF6,MRPS23,MRPS9,KRR1,PRR3,RPS2,RPL10A,MOV10,SPATS2L,E4F1,APOBEC3F,RPS15,EIF5B,MRPL17,NPM3,RPL4,SLC39A9,MRPS34,RPA2,RPLP0,RPL26L1,RPS14,FGF13,RPL13A,VIRMA,RSL24D1,RPS3,PRKRA,MRPS16,ATP1A1,CDKN2AIP,RPL7A,LRRC73,RPL26,FBXO7,CEP70 |
| 5.006e-08 | -16.81 | TPM3 (tropomyosin 3) | protein interactions | 7170 | 345 | 143 | 19454 | 5460 |
EZH2,PDHA1,RND3,RHOBTB1,B3GNT2,RAF1,ACTN4,SNAPIN,ISG15,PPP2R1A,JUN,TNPO2,TNF,PSMA2,TRIM26,TRIM37,VDAC1,RAD21,AHCYL1,BCKDK,MT3,AGR2,FKBP4,HSPB1,PSMD3,PRDX1,YWHAG,HSPB8,CTNNB1,LCA5L,RHOH,SUMO2,CCAR2,NUF2,FHIP1B,HSP90AB1,MAGED2,KLF3,PSMB7,PIH1D1,NDE1,WDR77,PPP1CB,UFL1,GPC1,PEBP1,FOS,HSPA8,CKB,BRCA1,SP1,HSP90AA1,VMP1,MYC,CDC123,CUL3,PSMD1,THAP7,BTF3,MCM3,EIF4A2,ACTB,ESR2,PRMT5,PHF21A,TNNI1,DISC1,CAPZA2,TAB2,RNF181,FURIN,FBP1,ATP5PB,IMP3,CHRM3,TP53,INSIG2,THAP1,TSSC4,RNF20,RIGI,MDC1,TFPT,KLF10,ECD,SNRNP70,MAP4,TMOD2,USP15,CALR,MOV10,DPP4,KXD1,COX5A,PGAM1,HDAC6,TPM3,THOC1,PRNP,TMPO,CDK9,KLF9,CD274,SMAD3,COX4I1,ADD1,METTL14,TMOD1,SH3GLB2,WTAP,CYC1,NEK2,CDK7,CFTR,KDM1A,SGF29,FBXW7,OIP5,PIAS1,HSPA5,DVL2,RHOU,BAP1,SOD1,GFM1,ATP1A1,CCHCR1,UBE2H,CSK,NDUFB10,AR,PPP1CC,DAPK1,HOMER1,SRC,JUNB,UQCRC2,CCNF,PSMA6,LURAP1,PSMC5,TRIM27,TRIM24 |
| 5.078e-08 | -16.80 | UTP14A (UTP14A small subunit processome component) | protein interactions | 10813 | 217 | 98 | 19454 | 5460 |
SAT1,P4HA2,NUP50,RNF10,STAU1,PPARG,VDAC2,TRMT6,RSRC1,GADD45G,RABIF,MAD2L2,ESR2,APEX1,MATR3,CCDC85B,MYC,HNRNPC,DNAJB6,FTSJ3,FBXW11,RPS24,COX8A,RPL31,S100B,DCP2,TRIM37,SOX2,NCSTN,E2F4,RPS11,CPE,SKA3,CHMP4C,HDAC11,EED,HP1BP3,SRSF1,SRSF10,NOP58,BUD31,RHOH,XPO1,CTNNB1,IFI16,PRPF19,PDZK1IP1,DDX23,CCDC106,RPA3,SIRT7,PNO1,LDOC1,AATF,FBXW7,SF3A1,HNRNPH3,TFIP11,RPA2,SSR1,CSNK2B,FGFBP1,PTEN,SF3B6,CCNF,ZNF330,EIF4A3,PDCD5,DEK,USP14,CEP70,RPF2,RPL7A,MAPRE1,RC3H2,BICD2,SEPTIN7,DHX9,SNIP1,ERLEC1,SNRNP48,RPAP2,EXOSC8,TP53,CBX3,RGS1,ARL4D,DKC1,CDC5L,RPS16,MIF,EIF2B2,CSNK2A1,ZNF24,LSM3,BRD3,CHCHD1,MPHOSPH10 |
| 5.111e-08 | -16.79 | SNU13 (small nuclear ribonucleoprotein 13) | protein interactions | 4809 | 276 | 119 | 19454 | 5460 |
USP15,RPS2,LSM3,SNRNP70,ZBTB2,CDK9,RBM42,MBD5,DKC1,TOP1,FZR1,CAND1,SYNCRIP,SRP14,RPL12,NUPR1,ACOT13,SURF4,RPL15,MAP1LC3B,EEF1A1,RPSA,KBTBD4,SMN1,RPS13,MEPCE,HNRNPK,KDM4B,HSD17B10,RPL23A,RRP7A,MAPRE1,UBE2H,ZNHIT3,LSM6,RC3H2,NAA50,SMURF1,RPGRIP1L,RPS3,CCNF,RPLP0,HEXIM1,ZNF326,RPA2,SNRPN,RPS14,PIAS1,RPL4,FBXW7,PPIH,RNF113A,HSPB2,PRPF4,BAP1,RHOU,RPA3,RPL23,TRA2A,RPL6,WWP2,IFI16,CNTROB,SRSF10,RPL7,LSM5,HNRNPL,NOP58,EED,CORO1C,MRTO4,RPL18,GTPBP1,SART3,RPS23,RPS11,CHMP4C,NGB,EZH2,RPS7,TPBG,RAF1,RPS4X,ROCK2,RUVBL1,SRSF7,RPS24,PCNA,CDKN2C,PABPC1,RPL31,RIT1,RPS5,LMNB1,SNRPB,PRPF31,BTF3,NOP16,HNRNPC,RAB11A,MYC,ESR2,RPL19,LRIF1,RFXAP,CLVS2,SF3B4,SNRPD2,RPL37A,DLST,KTI12,TRMT6,PIH1D1,CHST1,SAP18,POLA2,SSR3,TRA2B,SNRPA |
| 5.111e-08 | -16.79 | HMOX2 (heme oxygenase 2) | protein interactions | 3163 | 276 | 119 | 19454 | 5460 |
LAMP2,RAB5C,NDUFV2,RHOG,NDUFB8,RAB35,PHB1,CORO1C,ATP6V1A,ASIC1,NDUFS8,EGLN3,UQCRH,WIF1,DNAJC25,EEF2,STIM1,RPN1,PTRH2,PDHA1,CCR1,TMEM14B,CYP2C9,TMT1A,BLOC1S2,KRAS,EMC8,MYC,OST4,RAB11A,GGH,LMNB1,DNAJB6,LMBR1L,RETREG3,SEC61B,ATP5F1B,RBBP4,LRIF1,RNASEK,FAM234A,OTULINL,SEC62,DUSP22,ACAA2,ARMCX3,SKA2,MED31,DUSP9,TSPAN15,NMRAL1,RAB5A,AKAP1,JADE1,HSCB,NDUFS2,EEF1G,PHB2,PXMP2,STX7,TACR3,EMC4,ADIPOR2,LAMP3,CSNK2A1,POR,PTGER4,ESYT1,SHC1,PTPN1,SSMEM1,HSD17B11,RAC2,DNAJC1,ARF6,LMAN1,TMPO,CRB3,CCDC47,DDX39A,TMEM205,NDUFS3,NKRF,LPAR2,EMC2,RAB3B,CABCOCO1,RAB2A,VAMP5,CIAO1,TUFM,KCNMA1,ENDOD1,SNX5,CCNF,INPP5K,UQCRC2,ELOVL4,ALG2,SYNGR1,MGST3,CCR2,SEC63,CDC42,UQCRC1,ABHD5,ST7,LMNA,STOM,SSR1,CYC1,TEX264,TMX2,SYVN1,CYP2C18,DERL1,RAB9A,RTN4,PDHB |
| 5.124e-08 | -16.79 | TPI1 (triosephosphate isomerase 1) | protein interactions | 7167 | 259 | 113 | 19454 | 5460 |
BTF3,PMPCA,LDHB,ACO2,MYC,RIT1,MDH1,SP1,BRCA1,YWHAZ,S100A11,CKB,DLST,ENO2,CLIC4,TENT5C,PRDX2,AKR1C2,FKBP1A,ARCN1,PIH1D1,PPT1,PSMA3,TXNL1,HDAC5,PEBP1,GPC1,OXCT1,EMC1,UFL1,DDRGK1,CCL11,NDUFV2,HNRNPA1,CRIP1,PDIA3,NQO1,MT1X,TST,AGR2,GSTO1,GATD3,HYPK,SUMO2,SOX2,CCS,RAF1,B3GNT2,MOB3C,EZH2,PDIA6,HINT2,EWSR1,PCNA,VDAC1,KRAS,GMPS,CFL2,CFL1,SORD,UBE2H,SPOP,TRIM24,ENO1,CCNF,VIRMA,SUCLG2,LDHA,NDN,CFTR,NDUFAB1,UBA52,ATG16L1,DCTD,HEXIM1,UBE2M,GSTP1,HSP90B1,IDH2,RPA2,LDHAL6B,PRDX6,SQSTM1,PGK1,PML,SOD1,RPA3,BAP1,PIAS1,GAPDH,HDAC6,PGAM1,CALR,FGR,DHRS11,AKR1B1,DSTN,ARL10,AIFM1,SSU72,ESD,MIF,PGM1,PGM2L1,RNF8,SOD2,TFCP2,HSD17B10,SOS2,MAP1B,RIGI,MPST,HSPE1 |
| 5.124e-08 | -16.79 | SRSF10 (serine and arginine rich splicing factor 10) | protein interactions | 10772 | 259 | 113 | 19454 | 5460 |
EEF1G,STAU1,HSCB,B9D2,UFL1,TRA2B,SAP18,PSMC1,NKAPD1,SNRPA,NMRAL1,LARP4B,USP39,TRMT112,PABPC5,DUSP14,SNRNP40,RPL19,RAN,MRPL13,SMU1,DCAF4,MYO6,YWHAZ,THOC6,HSP90AA1,SFN,MYC,NUP42,H1-6,SRSF4,HNRNPA2B1,PABPC1,SRSF7,CHMP4C,EZH2,NFKBIL1,RAF1,B3GNT2,EEF2,NUP37,NCSTN,MPP1,PAIP1,HSP90AB1,DHX15,PHB1,SRSF1,CLK4,EED,MRPL18,DDX23,HSPB1,YWHAB,MAGOH,MPHOSPH6,HNRNPD,RB1CC1,WWP2,RPL6,TRA2A,DDRGK1,YWHAH,HNRNPA1,YWHAG,HMGB1,FBXW7,NHP2,PIAS1,RPA3,CLK1,METTL14,RPA2,DYRK2,RBMS2,DAPK1,NDN,SRPK2,DYRK1A,EIF4A3,RC3H2,UBE2H,ELAVL2,ZNF687,PTPN11,PPP1CC,FBXO7,RPL26,KPNA2,SRSF12,TCOF1,SNIP1,ZC3H11A,IK,NUPR1,ILF2,RPSA,EXOSC8,APOBEC3D,MRPL50,CAND1,FZR1,SPPL3,SLAIN2,ZBTB2,DKC1,MYL12A,ALDH1A3,CHCHD1,SNRNP70,ZMYND11,GAPDH,CSNK2A1 |
| 5.127e-08 | -16.79 | E (envelope protein) | protein interactions | 43740570 | 296 | 126 | 19454 | 5460 |
TPM3,GAPDH,KARS1,ESYT1,SEC23A,PSMB1,ALYREF,RPL32,SRP14,HACD3,DKC1,HTRA1,THOC1,RPS16,CAND1,YTHDF2,TP53,RPSA,GNAI3,NHERF1,ARPC3,RNF167,SLC25A11,CSE1L,TMEM33,GORASP2,ATP5F1A,CREB3,ATP1A1,OAT,AP2A1,SMPD2,BBS5,ALB,GANAB,EIF4A3,DEK,CDC42,SEC22B,SPTBN1,HSP90B1,H2BC11,SDCBP,LMNA,H2BC12,DLAT,HNRNPH2,BANF1,POLDIP2,ZC3H15,GRPEL1,NHP2,YKT6,XPO1,YWHAH,PDIA3,RPL23,AHSA1,DDX1,CHST11,WDR12,SRSF1,PSMB5,MRTO4,RBM5,THOC2,NUP35,SNX2,SPTAN1,MEAF6,RPS10,EIF2S1,ERLIN2,EEF2,RPL29,MARCKSL1,CAAP1,PDHA1,RPN1,SRSF7,PDIA6,PCNA,MYO1B,JAK1,SSRP1,POLDIP3,VDAC1,ETFA,ZBED1,MCM3,MCM4,MRPL16,RPL39,RAB11A,LDHB,HNRNPC,MDH1,LMNB1,AP2M1,DLST,VDAC2,CHP1,CBX5,ACTB,STAT1,MATR3,MRPL12,PRDX3,PGRMC1,LNX2,PIP4P2,NCOA5,H2AC1,CTBP1,USP39,LMBRD2,VAPB,HADHA,EP300,DDX39B,THOC3,PHB2,YTHDF1,NOP53,RNF5,FXR2 |
| 5.137e-08 | -16.78 | NOC3L (NOC3 like DNA replication regulator) | protein interactions | 64318 | 206 | 94 | 19454 | 5460 |
UBE2H,RC3H2,RPL7A,RPL22,SRPK2,RHOJ,RPL13A,ZNF622,PRKRA,FGFBP1,ZNF330,EIF2AK2,TNFRSF1B,MACROH2A2,RPL26L1,RPLP0,RPA2,FGF13,BRIX1,WDR55,RPL4,NPM3,DGCR8,MTDH,PNO1,NLE1,SIRT7,RPA3,RPL10A,H2AC4,PLEKHO1,ZBTB2,SURF6,FZR1,ARL4D,KRR1,SRP14,SRP72,RBM34,AURKAIP1,TP53,RIGI,RPL17,PSMB10,H3C1,RPL23A,RPL3,TCOF1,SNIP1,H1-1,DNAJB6,PSKH1,ZNF668,CUL3,MYC,APEX1,ESR2,RPL19,RPL10,SNRNP40,RPL35,RPL7L1,RPL37A,DLST,LMBR1L,FAU,USP39,APOBEC3C,STAU1,HSPA8,LHX2,DICER1,DDX23,WDR12,DDRGK1,IFI16,LYAR,NOP58,SRSF1,RPL8,RPL18,CHMP4C,EZH2,MAK16,SOX2,H1-3,MAGEB10,SRSF4,RPL28,HMGN4,KRAS,COX8A,RPS24,RPL31 |
| 5.195e-08 | -16.77 | POLR2B (RNA polymerase II subunit B) | protein interactions | 5431 | 351 | 145 | 19454 | 5460 |
WDR77,PIH1D1,MED31,SNRPA,AKAP1,MED13L,HSPA8,STAU1,MED11,UFL1,TRIM52,CUL3,APOBEC3B,MYC,LMO2,SNRPB,BTF3,H1-10,PSMD14,MED10,PFDN6,ILK,POLR1B,RIT1,RPS5,PFDN2,PELO,NFKBIA,LMBR1L,GTF2F2,GTF2F1,POLR2F,ANAPC2,POLR3B,PRMT5,GPN2,INTS10,MED17,FBXO22,TUBB,RPL35,ESR2,POLR2B,SUPT5H,MED9,RAF1,GTF2E2,PPP2R1A,HDAC11,TUBB4B,SKA3,MOB3C,POLR2D,POLR2C,FAM168A,TESK2,RPAP3,RUVBL2,KGD4,RUVBL1,CDK20,G3BP1,KRAS,SSRP1,FLOT1,WWP2,MAPK4,IFI16,MAP3K14,XPO1,CRTAP,MED4,HAX1,HNRNPD,POLR2L,PHB1,RPRD1A,WDR82,POLR3F,EGLN3,ATG16L1,INTS6L,CDK7,ZSCAN1,POLR1D,CCNH,MED30,WWP1,RPRD1B,RPA2,DCTN4,BAP1,RPA3,SQSTM1,TCEA1,ELOF1,FBXW7,HMGB1,KDM1A,IRF7,POLR1H,CIAO1,MED22,SUB1,PPP1CC,PRKACB,UBE2H,CCNF,MACROH2A1,POLR3H,INTS12,PTEN,SRC,VIRMA,SMURF1,TP53,KBTBD4,MAP2K3,PSMB9,EEF1A1,RPAP2,CDK8,POLR2G,TCOF1,SNIP1,CPNE2,DNAAF10,PSMA5,SEM1,PTGES3,MDC1,PDRG1,ERCC3,GTF2E1,MED29,MED21,MED27,DNAJC7,GTF2B,TOP1,POLR2I,FZR1,CAND1,ASNSD1,NCBP2 |
| 5.206e-08 | -16.77 | VPS13C (vacuolar protein sorting 13 homolog C) | protein interactions | 54832 | 103 | 55 | 19454 | 5460 |
DCAF11,DNAJC7,COMMD5,LAMP3,RAB32,LAMP2,SLC25A46,RAB5C,LMAN1,PLGRKT,RAB1B,HNRNPL,C2CD2,RAB35,EEF1AKMT3,ARL10,TMEM31,EZH2,RAB4A,FAF2,KRAS,RBBP7,ARL5B,HNRNPK,RAB3B,CDK20,BAG2,RAB1A,HNRNPA2B1,LAMTOR1,TRIM23,DCAF4,AR,MYC,RAB2A,CIAO1,RAB11A,UBTD1,VIRMA,RAB14,RHOJ,SGTA,CYB5R3,RSAD2,VAPB,HSP90B1,DET1,ATG16L1,PIP4P1,STAU1,RAB30,RAB9A,AKAP1,DVL2,BANF1 |
| 5.258e-08 | -16.76 | TFAM (transcription factor A, mitochondrial) | protein interactions | 7019 | 398 | 161 | 19454 | 5460 |
FBXW11,MRPS25,RIT1,RAB11A,CUL3,PMPCA,PYCR1,MYC,AUH,TOMM40,BTF3,RPL7L1,RBBP4,RPL35,MRPL23,ATP5F1B,NDUFAF4,PARL,ELK3,DLST,IRF2,VDAC2,TACO1,ATP5PO,KLF3,NDUFA5,BET1,AGTRAP,MRPL12,EEF1G,HSCB,NDUFS2,UFL1,MRPS7,HADHA,HSPA8,LHX2,MRPS26,MRPS35,WWP2,DDX50,MTRF1,BAZ1B,DDRGK1,CTNNB1,NDUFV2,YWHAH,ELK1,NDUFS8,PHB1,GATD3,EED,PDHA1,CHMP4C,NDUFS6,NDUFA12,E2F4,ETFB,HSDL2,B3GNT2,RAF1,TOP3B,PPP2R1A,H1-3,SOX2,ETFA,KCTD17,KGD4,KRAS,RBBP7,IMMP2L,MRPS17,PPAN,HSPD1,MRPS11,COX8A,HINT2,MRPS16,UBE2H,DNAJC19,EPHA2,PYCR2,SMARCA5,NDUFAF2,USP14,MRPS21,PNP,MGST3,UQCRQ,TECR,MRPL53,CCNF,ACAT1,MRPS28,GRM2,HSP90B1,QRSL1,COX6C,CDK1,MRPS34,LMNA,MTRES1,CYC1,WTAP,LEMD3,TFB1M,HEXIM1,ATG16L1,KLF12,NDUFAB1,MRPL10,MRPL40,MRPL41,HMGB1,NME4,PDHB,MRPL20,POLDIP2,GRPEL1,PPM1G,GFM1,TWNK,SNRNP70,BRD3,COX5A,GRSF1,COPS5,MRPL50,FZR1,CAND1,MRPL24,ZBTB2,MRPS23,ATP5PD,DBT,KRR1,COX4I1,MGME1,HRAS,MRPS9,NDUFS3,NUPR1,FURIN,MRPL47,NDUFA2,ATP5PB,METTL15,AURKAIP1,PPIF,HADH,MRPS33,PDE12,RIGI,MRPL22,MRPS18C,MEPCE,SFXN1,ATP5PF,HSD17B10,ABCE1,MRPS18B |
| 5.294e-08 | -16.75 | PML (PML nuclear body scaffold) | protein interactions | 5371 | 923 | 332 | 19454 | 5460 |
FHL3,UBE3A,BAG2,PCNA,JAK1,PLSCR1,SLC25A5,HSPD1,ZYX,AHCYL1,GTF3C3,RPS27A,TMED7,PPWD1,ASF1A,ZBTB16,LASP1,GTF2E2,TULP3,PPP2R1A,JUN,E2F4,ARFGAP1,RBM12,SART3,MTMR2,EZH2,HP1BP3,RPLP1,MAP1LC3A,IGBP1,MRTO4,CBFB,DNM2,SP2,THOC2,RPL8,DHX15,PRPF18,EGLN3,RPL7,ZNF207,SIAH2,HSPB8,MAP1S,PRDX1,LYZ,AHSA1,CSTA,TERT,PSMA3,NUP50,BIRC2,EXD2,MCRIP2,SKP1,AZGP1,CSRP1,ZBTB39,PYGB,CDSN,PPP1CB,RTF2,ARMCX3,MED23,PPARG,RPS9,EIF3K,RPL19,USP5,SIAH1,TAB1,TUBB,JPT1,CUL3,PYCARD,NIBAN2,DSN1,RMI1,LSM14B,SP1,YWHAZ,MYO6,LMNB1,BRCA1,FAS,PC,KLF10,RPL23A,CACUL1,ZC3H11A,EIF3E,RIGI,MDC1,RNF20,RPL15,MAP1LC3B,YTHDF2,NDUFA2,PDLIM4,TOPORS,TES,RB1,SRPRA,SMAD3,CAV1,MDM2,COG1,SUV39H1,GLO1,GTF2E1,HDAC6,SPATS2L,GMPPA,ERCC3,NFKB1,TOPBP1,PSMD7,SQSTM1,MAVS,RTN4,MTDH,HMCES,PRPF4,HELLS,PIAS1,RPL4,FBXW7,PDHB,GTF2I,IRF7,PPP1R2,CDK7,SYNRG,SEC22B,UBA52,MACROH2A2,OXSR1,HNRNPH3,HSP90B1,PICALM,PAK5,TIMM23,LMNA,CDK1,SFXN2,CHCHD6,UBE2I,SENP5,TRIM24,TRIM27,CTTN,PELP1,CCNF,CEP97,CTTNBP2NL,UQCRQ,RPL13A,TMOD3,LDHA,NONO,RPL26,RUNX1,ZNF687,CDC16,SMAD2,TRIM21,OAS1,RPAP3,RINT1,TOP2B,CCT8,S100B,FBXO3,SATB1,KRAS,ZNF609,NAB1,RPS7,EEF2,TRAF2,DHX38,RPL18,SLC1A2,PDHA1,HDAC11,STX5,MAGED2,PRCC,HOMER3,SIN3A,HSP90AB1,SUMO3,SUMO2,MITF,RPS10,TBC1D5,CTNNB1,DDX50,IFI16,HSPB1,TNNC2,GSTO1,TRIM22,EP300,HSPA8,FOS,HIRA,RFC4,SLU7,NANP,TRIM52,ZBTB5,SAP18,ARMCX2,OXCT1,EYA3,STAU1,CNPY3,FDFT1,NUFIP2,EIF4B,PAK2,MXD1,PHF21A,GTF2F2,ZMYM2,ADH1B,CMTR1,ZNHIT6,DLST,VDAC2,APEX1,ESR2,SNRNP40,STAT1,STAT2,PCCB,BAG3,KANSL3,LDHB,MYC,CREBBP,MDH1,COP1,PSMD14,RPL3,ZBTB25,ZNF451,BHLHE40,MAP1B,NOSIP,PALM2AKAP2,LPCAT3,HNRNPK,RBCK1,CSE1L,TGFBR2,ZMYM4,ZMYM3,H2AX,WBP11,ESS2,TP53,MTCH2,PSMC3,NUPR1,SLC25A24,IK,TFCP2,DDX42,CDK6,ZNF280B,IER3,GTF2B,SYNCRIP,ACSL4,CDC5L,SLAIN2,TMPO,MYL12A,SHPRH,MIF,GAPDH,EDC3,CSNK2A1,DNAJB2,USP2,ACOT8,MAP4,TAF9,RPL24,SMCHD1,NR1I3,DERL1,TNFAIP1,DLAT,PGK1,PML,SNX11,NBN,DDX46,CLU,HSPA5,BCL6,MARS1,TOMM20,EIF4E,RBM22,HDAC3,NTPCR,GTF3C4,CD2AP,SUMO1,ACACA,PTPMT1,PSMC5,SRP54,CSNK2B,LIG3,ZBTB33,UBN1,PPP1R10,PLAGL1,IRF2BP1,BUB3,CFL1,PTPN11,RPL7A,SUGP1,RPF2,EIF3G |
| 5.350e-08 | -16.74 | MGST3 (microsomal glutathione S-transferase 3) | protein interactions | 4259 | 262 | 114 | 19454 | 5460 |
SCN3B,TOMM40,SLC1A3,CGRRF1,PLN,ZMPSTE24,FAXDC2,VDAC2,CYB5R3,EDNRA,TMEM229B,APLNR,CHCHD3,ATP6V1C1,TOMM22,AGTRAP,BET1,TIMM13,ATP5PO,SMCO4,FAM3C,EXD2,ATP5MK,TSPAN15,NMRAL1,HADHA,AKAP1,UFL1,STX7,PLPP4,DDRGK1,FXYD6,NCR3LG1,MRPS26,OCIAD2,RAMP3,WIF1,RAF1,NEU1,PPP2R1A,PDHA1,AQP3,CTSA,MYO1B,COX8A,USP30,TMEM60,VDAC1,SLC25A1,ARL6IP6,HMOX2,PLP1,UQCRC2,VAMP3,CDIPT,CCNF,F10,CYBC1,MGST3,UQCRQ,SEC22B,UQCRC1,PLP2,COX6C,RPA2,LMNA,GRM2,HSP90B1,SYS1,CLRN1,CYC1,TMX2,SLC39A9,RPA3,LRP10,MAVS,SLC7A1,PDHB,IRF9,COX5A,COPS5,TMEM107,SLC2A1,SLC35A1,HRAS,PTPN1,EHBP1,COX4I1,CDCA3,SVIP,FUNDC2,TOMM70,ATP5PD,RAP1A,UBIAD1,MTARC2,TMEM205,NRM,TFRC,NDUFS3,VAC14,SLC25A20,MRPL49,STX8,SLC25A11,ATP5PF,TSPAN17,ERG28,UNC50,LPAR2,YIF1A,NUP107,NSG1,FKBP8 |
| 5.375e-08 | -16.74 | MRPL46 (mitochondrial ribosomal protein L46) | protein interactions | 26589 | 187 | 87 | 19454 | 5460 |
MED23,MRPS18A,MRPL12,MRPL57,HSCB,EXD2,NGRN,RIT1,PMPCA,FMC1,MTG2,MYC,AUH,MRPL16,PSMD1,RPL35,MRPL23,RPL10,RPL19,PARL,MTG1,CCDC90B,TACO1,MRPL13,MCPH1,PDHA1,E2F4,MARCKSL1,TOP3B,KRAS,IMMP2L,PSMD12,HSPD1,COX8A,HINT2,SKIC8,MRPL18,RHOG,MRPS26,RPL6,IFI16,MTRF1,ETFRF1,DDRGK1,MRPL9,HNRNPA1,KCTD10,GATD3,FAHD1,MTRES1,RBMS2,MRPL10,NDUFAB1,MRPL41,MRPL40,MRPL17,MRPL20,GFM1,UBE2H,TUFM,ATP5F1A,MRPL53,NDUFS3,DISC1,MRPL49,MRPL51,GFM2,MRPL47,MRPL11,METTL15,AURKAIP1,RPL17,MEPCE,MRPL52,SEMG2,EMC2,RPL3,RPL23A,TMEM70,SNRNP70,GRSF1,MRPL50,FZR1,MRPL24,MALSU1,MGME1,SSBP1 |
| 5.411e-08 | -16.73 | GNAS (GNAS complex locus) | protein interactions | 2778 | 220 | 99 | 19454 | 5460 |
GNB4,UFL1,ADRB2,NMRAL1,HSPA8,TTC1,PMAIP1,GTF2H5,ARMCX3,TSHR,RND2,BET1,GNB1,RANBP6,TAX1BP1,MIDEAS,CDKL2,LAMTOR1,RHOB,CAV3,MYC,CUL3,KRAS,TRIM37,RUVBL1,GNA11,BCKDK,GNAQ,EZH2,GNG3,B3GNT2,RAF1,TOP3B,EGLN3,STK3,HNRNPL,RHOH,MAGED2,YBEY,THOC2,FBXO32,DUSP6,CBL,HAX1,BCL2L1,RHOG,AGR2,XPO1,ADCY2,YWHAG,WWP2,HSPA5,RGS2,CERS2,VIPR1,RNF113A,BAP1,RHOU,LHB,RPA3,PAK5,RPA2,METTL14,CDC42,CFTR,EIF4H,RHOJ,CPT2,CD47,STUB1,CCNF,OPTN,METAP2,NRP1,CRHR1,UBE2H,SPOP,AR,VAMP5,SOCS2,RIGI,GNG5,ADRB3,NUPR1,TFCP2,MAP1LC3B,GNG10,CHRM3,ADORA1,TP53,MDM2,CDC5L,SLC25A12,FZR1,DNAJC7,CD81,GNG2,HDAC6,DPP4 |
| 5.411e-08 | -16.73 | SLC25A12 (solute carrier family 25 member 12) | protein interactions | 8604 | 220 | 99 | 19454 | 5460 |
ATG16L1,TIMMDC1,CFTR,COX6C,RPA2,TIMM23,METTL14,GHITM,SAMM50,CYC1,DVL2,RPA3,NF2,SLC25A51,MLF1,CSK,NDUFB10,ARHGAP21,CHCHD4,CCNF,CHCHD6,ATP5PB,FAM162A,MTCH2,MGARP,APOO,TIMM8A,GPD2,NDUFS3,SLC25A24,MAP1B,SFXN1,CLPB,COX5A,GLO1,SMIM12,MRPS9,TIMM8B,SMAD3,AIFM1,COX4I1,CDCA3,FMOD,ARL6IP5,TMPO,TOMM70,MRPL24,MTX2,TIMM13,TIMM29,NDUFA5,ATP5IF1,UFL1,EMC1,YTHDF1,PHB2,HIGD2A,COX6B1,NDUFB7,MYC,TM9SF4,PMPCA,TOMM40,MLF2,COX11,KIAA1191,CNIH4,HTRA2,LMBR1L,DLST,PELO,FBXO22,CHCHD3,ESR2,PARL,TXNRD1,E2F4,NCSTN,NUDCD3,SOX2,EZH2,NDUFA4,ETFA,IMMP2L,PAEP,SYNJ2BP,AK2,MRPL18,UQCC6,HAX1,HSPB1,PHB1,GJA1,BRD9,PCSK9,AGK,EGLN3,CACYBP,COX14 |
| 5.444e-08 | -16.73 | SNRNP200 (small nuclear ribonucleoprotein U5 subunit 200) | protein interactions | 23020 | 410 | 165 | 19454 | 5460 |
LSM8,HSPA5,HMGB1,FBXW7,KIN,RNF113A,PPIH,TCEA1,RPA3,BAP1,PRPF4,SIRT7,HEXIM1,TFIP11,UBE2M,RPA2,METTL14,LSM2,ELP3,SF3A1,TXNL4A,SNRPN,VIRMA,SRPK2,NDN,KCTD9,PHAX,PTEN,UBE2I,MACROH2A1,CCNF,GCFC2,TUBA1B,EIF4A3,ATP1A1,UBE2H,RC3H2,USP14,AR,KPNA6,PDRG1,MEPCE,GNMT,SNRPG,RIGI,PTGES3,TSSC4,CTNNBL1,CHMP1B,HUWE1,LSM4,DNAAF10,THRAP3,RAB27A,SNIP1,MAP1B,NUPR1,EEF1A1,CD2BP2,FBP1,TMPO,RBM42,CWC15,ZBTB2,CDC5L,CAND1,DCUN1D1,FZR1,TOP1,ARL4D,CD274,RCHY1,KIAA1143,ECD,SNRNP70,COPS5,ZMYND11,COIL,G3BP2,UFL1,TRA2B,STAU1,DUSP26,EEF1G,SF3B1,HDAC5,EP300,HADHA,DDX39B,SNRPA,PIH1D1,USP39,TIRAP,CDKN1A,MTF1,PRKAB1,POLR2B,PPP5C,SNRPB2,MATR3,TUBB,SNRNP40,SNRPD2,SF3B4,SMU1,SNRPD1,CMTR1,HSP90AA1,THOC6,RIT1,LMNB1,BRCA1,BTF3,RNF40,PRPF31,SNRPB,CREBBP,MYC,CUL3,HNRNPC,CUL2,GTF3C3,SSRP1,AHCYL1,KRAS,G3BP1,RUVBL1,RUVBL2,EWSR1,TOP2B,PABPC1,HNRNPA2B1,GPBP1L1,SART3,SNRPE,EZH2,TUBB4B,SMNDC1,CHMP4C,ISG15,LGR4,DHX38,SUPT5H,DHX15,SUMO2,SNRPA1,SNRPD3,EED,COPS2,SIN3A,PHB1,RBM5,SRSF1,HSPB1,YWHAB,MAGOH,SKIC8,DDX23,AGR2,YWHAG,HNRNPA1,NT5C2,DDRGK1,PRPF19,WWP2 |
| 5.555e-08 | -16.71 | cell junction | cellular component | GO:0030054 | 2224 | 755 | 19108 | 5553 |
KCNJ11,ATP8A1,TAC1,GID8,KPNA1,STXBP1,PAK5,RAB3A,CHRM4,FZD3,ZMYND19,KIF3B,EXT1,GJA1,ZDHHC15,CD2AP,RGS10,ZYX,SCN2B,SEPTIN6,RAB13,DAPK1,ACTB,SLITRK1,AQP3,GAB1,ARF6,GABRA1,RPL22,ARHGEF6,ITGB8,CLDN14,KIT,DNM2,ARL6IP5,MOB4,OSBP,CLDN11,DLGAP4,CDK5,SYNGR1,IGSF11,RPL13A,LCP2,SLC35F1,SLC16A10,CLDN3,LASP1,STK38L,GDI2,VPS18,DCTN4,OLFM2,NLGN1,HSPA5,FAM81A,DNAJC5,PDLIM4,HRH3,CFL1,CCNF,VPS54,UBA52,SLC6A4,LRRTM2,CIB2,CPLX1,ARL14EP,SDCBP,RHOU,ATP6V1G2,SRSF10,EZH2,INSYN2A,REXO2,CTTN,RPL7A,GHRL,MECP2,RAP2C,TMEM108,VAMP1,ACTN4,CLU,SYP,RASGRP2,CD59,JUP,WASL,ALCAM,SYNDIG1,RPGRIP1L,HSPB1,PKP4,PCDHB13,RPS3,RPL23,HTR5A,ELAVL4,KCNA3,CLDN4,CLN8,RAP1A,TUBA1A,SYPL1,ADORA1,ICA1,ABCC2,SYNGR2,FCHO2,PCDH9,TRIM29,UBN1,VTI1B,NCDN,SNCB,BAALC,ROGDI,EPHA4,CHP1,GABRA2,CACNB3,CPLX2,RPS16,RIMS3,EHD3,LRRTM3,C1QL1,SHC1,TES,SDC4,RAB40AL,RPS7,C1QL3,CNN3,HCRT,CARTPT,DRP2,KCTD16,DISC1,RAB3B,POLDIP2,PSMA3,MFAP3L,SPTBN1,HPCA,AKAP12,PTK7,CLSTN3,GRIA2,B4GALT1,CD46,GRIA1,CLDN12,EFNB1,MT3,TNR,SSX2IP,RAB33B,SARM1,IGF2BP1,OPHN1,VEGFA,CDC42EP4,SLC35G2,EEF2,KCNIP2,KCND2,ZNRF1,P2RY4,CD2,RPL10A,OPRM1,NSG1,OXTR,HSP90B1,RGS7BP,KCTD12,GPC1,RPL28,TRIM15,CNTN1,PDLIM3,PSEN1,MSN,MMP14,LAMTOR3,CAPN2,CPEB1,ADD1,STX7,ABHD6,CD9,PPP3CA,GPR176,LY6H,TM4SF20,UTS2,STX12,GPC4,NPTX1,RND3,CLDN1,LGI3,PHACTR1,LIMS2,DES,NQO1,CTNNA2,SCAMP5,APH1A,ADORA3,RALA,CHRM1,ARF1,GNB1,PSMC4,SYN3,RAB5C,RPS6KA4,PTPRZ1,PGRMC1,PRKCB,CRKL,ATP2B4,CAP2,GRM1,STX1A,PPFIBP1,HNRNPK,SNTA1,NTRK2,NTF4,DSTYK,HRAS,CFAP418,CACNB2,SLITRK5,ITGA6,RPS10,KCNH1,ATP1A1,MAP1B,AKR1A1,ATP6V1G1,NUDT9,RPS17,SLC1A1,GPHN,ZC4H2,CHMP2B,SSPN,L1CAM,RPS5,SH2D5,JAK2,CHRM5,SRC,SLC6A11,GRID1,AP2S1,SLC4A8,CLDN6,LAMB2,GTF2A2,PDE4B,HNRNPF,ATP6V1D,LYNX1,STX11,RNF10,CXCR4,SLC4A10,HNRNPA0,NAPA,AP2A1,NETO2,ASIC2,ESAM,WNT7A,CBLN1,YES1,CAMKV,RABAC1,FCGR2B,TPPP,CBL,CCND1,CASK,CAPN1,CYTH1,SLC6A6,TMOD2,KRAS,AP3S2,CTTNBP2,ADD2,ARF4,SIGMAR1,F11R,PSENEN,RPL31,SNAP25,DAG1,VAC14,DLG4,SYT2,RPS11,LIN7B,GLRA1,TPBG,DROSHA,AGER,NIBAN2,WASF3,GPM6A,CHRNA7,ATAD1,DLG1,STX16,RPL12,PCDH17,CLDN9,EPHA2,GABBR1,ITGAV,SLC2A1,LRFN3,RIC3,NEU1,CDSN,FLCN,TNIK,PARD6A,PSD2,SPTAN1,ATP6V1A,ACHE,CRB3,PPFIA3,PLG,AKT1,B2M,ICAM1,CRHBP,BMPR2,ADRB1,SLC1A2,ARHGAP21,PYM1,MTMR2,GRAP,MIOS,PAK6,CCN3,TGFB1I1,DPP4,STX6,RIGI,GSK3A,BVES,PTEN,PPP1R12A,MAPRE2,SLC6A1,FHL3,MYH2,NDE1,PDE2A,OLFM3,CAMK2N2,GABRB3,MPP1,ABHD17A,SLC6A12,RAP2B,YWHAZ,RPS27A,TMOD3,C1QL2,RPL4,GUCY1B1,CDH11,TBC1D24,RAB8B,MTDH,DRD3,MAP2K1,RPS23,HNRNPD,RPL18,RPS2,SNAP29,KCNA2,LIN7C,RS1,CTNNA1,RPL24,ELFN1,CHRDL1,BCL2L1,RAP1B,FERMT2,SLC6A2,NCKAP1,PSEN2,FLRT3,BACE1,GAD2,USP14,SLC6A3,TMUB1,ARFGAP1,PLXNC1,PALS2,SNAP91,GRIK1,COPS5,YWHAG,VAMP7,RPL3,PAFAH1B1,CTNND1,ARPC2,TUFM,PLCB1,ELK1,DRD1,FABP5,AIF1L,CNR1,RPL8,GNAI2,PHB2,ARPC3,JAK1,SLC16A1,IRF2,PRRT1,MACO1,CSRP1,SPECC1L,ADGRL3,RPL26,MAPRE1,HOMER1,CRYAB,UBE3A,RAB11B,KCNMA1,SLC8A1,STX10,NPY,CACNG3,HRH2,EIF5B,CHRM3,FGF13,CPSF2,ILDR1,HTR1A,CD99L2,RPS4X,LAP3,RAB3D,C1QC,LRRTM1,GABRG2,CSK,PLP1,OPRK1,PABPC1,GTF2F1,CLDN22,SLC29A1,PRNP,MDC1,EPS8,CYTH2,NEFL,THY1,RPS13,GNG3,HOMER3,EIF4EBP2,SYNGR3,PIK3CA,COMT,RAB11A,RAB6B,GABARAP,RPL27,COPS4,MPST,ITGA2,OCEL1,G3BP1,USP8,CAV2,NINJ1,PRSS12,PNOC,VAMP2,MRPS18B,LGI1,ITGB5,RPL19,NPTN,CDH13,ACTR2,MEF2C,SVOP,KCND3,INSYN2B,RPS26,FAM107A,DPEP1,CD81,FZD4,PDIA3,DBH,LPAR2,CAMK2N1,PICK1,ATAT1,NCSTN,RAB5A,NOS1AP,STK38,NPR2,FXYD6,TCAF2,EIF3D,UCN,VAMP5,RPL37A,FBP2,TMEM47,SLC1A3,MYH1,KCNJ3,SIPA1L1,KCNMB1,UBE2L3,EXOC3,LRP6,SLC31A1,MEF2B,GLRB,ATP6V1C1,NPBWR1,ATP1B1,NTNG2,SEMA4C,PPP1CC,FLRT2,CACNB4,CDC42SE1,PPP1CB,PICALM,SNX14,IGSF21,CALY,LAMP5,PTN,JAML,ATP1A2,NETO1,PPFIA2,HSPA8,GJA10,CCDC85B,AP2M1,SYNGR4,GPR37,EIF2S2,LRRC4,STXBP6,CDH7,HAPLN2,CTNNB1,ATP6AP2,NF2,INA,SNAP23,RIMS4,KCNJ10,ASIC1,ILK,IQSEC1,TRIP4,SNAPIN,RPL9,RPL15,PTPN5,RPS20,HNRNPH2,LCP1,GNA11,RPS28,RPL6,YWHAH,GJB1,EPCAM,FLOT1,ASCC1,RAC2,SYNPR,CDK4,RPLP2,HMGA1,KCNJ2,FCHSD2,STAU1,ROCK1,EIF2S1,SCN1B,NLGN2,CLDN24,RIT2,PAK2,CBLN2,PIK3R1,RTN4,IL1RAP,PPIA,TADA1,AJM1,RAB4A,NPY5R,MAP1LC3A,CD151,KCNJ8,PIP5K1A,MME,C9orf72,GRM2,NDFIP1,INSYN1,CTBP1,CALR,TSPAN15,KRIT1,MKLN1,PLAA,CUL3,NECTIN2,PPP2R1A,RPLP0,RRAS2,FRRS1L,RHOB,EIF4E,RANBP6,SLC32A1,NRP1,ITK,CDK5R1,KCNC1,SYT4,SLITRK2,RPS15,HTR1F,NRN1,EIF3E,DCP2,CBLN4,GJC1,YWHAB,MPZ,SV2B,HTR2A,VDAC1,EIF4A3,TRAPPC4,KCNB1,PLCXD3,SLC6A7,SPOCK1,RPS29,GIT2,ZDHHC17,RAB23,RAP2A,RPLP1,KLHL24,SLC39A3,NGDN,GABRB2,ATP1A3,RAB3C,CBLN3,LRRC4B,LARGE1,CDCA3,LPXN,RANGRF,P2RY1,VAMP3,CLIC4,ACTL9,PRKCE,SLC17A5,STAC3,RPL7,SST,S100A11,DGCR8,PIK3R2,CNP,TMEM204,PPT1,CNTN2,CLDN8,RHEB,PMP22,CPLX3,CHN2,SCHIP1,CHRNB2,INPP4A,NOG,DLG3,SLC18B1,GLRA2,RHOG,PPIB,CORO1C,CYFIP2,LPAR1,BORCS5,EFNA5,FGF12,KRT8,PDYN,RPS9,NME2,GJB2,CDC42,GNAQ,VEZT,RPS14,MAP1S,MCMBP,CAV1,SNCG,CAV3,LHFPL4,CNTNAP1,LYPD6,NCK1,CDH8,TMED9,HACD3,TIAM1 |
| 5.692e-08 | -16.68 | IPO7 (importin 7) | protein interactions | 10527 | 285 | 122 | 19454 | 5460 |
BAP1,RPA3,PPM1G,SIRT7,SYVN1,SQSTM1,FBXW7,HSPA5,ATG16L1,CFTR,RPA2,METTL14,RNF146,HECTD1,CCNF,ZNF330,PTEN,RPGRIP1L,VIRMA,SLC25A1,SPOP,TXNIP,RIC3,ZBTB38,NRP1,PPIG,UBE2H,DNAJC19,METTL18,NOSIP,HAPSTR1,RPL23A,NUP107,KPNA2,SOCS2,FBXO25,VPS16,H2BC14,TMEM126A,COMTD1,CHRM3,MAP1LC3B,AURKAIP1,RPL15,SMAD1,TFCP2,SIGLECL1,CAPZA2,DNAJC2,APEH,PTPN1,CD274,TES,CAND1,VTI1B,DNAJC1,PRNP,MDM2,CDC5L,KARS1,HDAC6,MPHOSPH10,SHC1,SSX2IP,LCA5,HSPA8,EP300,RP2,STAU1,FAM234A,H1-5,SEC62,RND2,CSNK1A1,TRMT112,PIH1D1,SLC25A3,LMBR1L,BAD,RAN,FAM43A,RPL35,MAD2L1,RPL19,ESR2,MYC,CUL3,FAS,H1-10,DCAF4,BRCA1,NSA2,RIT1,ILK,RPL31,EFNB1,COX8A,KRAS,G3BP1,B3GNT2,RAF1,RANBP1,NUP153,ASPM,SOX2,RPS7,EZH2,CHMP4C,RPL18,PHB1,IGBP1,HP1BP3,DIRAS3,HSP90AB1,CEP19,PIK3R1,IFI16,FAM174A,PFDN5,DDRGK1,RPL23,HSPB1 |
| 5.692e-08 | -16.68 | P4HA1 (prolyl 4-hydroxylase subunit alpha 1) | protein interactions | 5033 | 285 | 122 | 19454 | 5460 |
RNF113A,SYVN1,BAP1,HSPA5,IRF7,PDHB,CFTR,CDC42,UQCRC1,CPSF4,SF3A1,CYC1,MET,UBE2M,HSP90B1,FGFR1,COX6C,SF3B6,CCNF,UQCRC2,INPP5K,CSTF3,SMURF1,CTSB,MGST3,COPE,TUFM,HMOX2,DNAJC8,ZNF687,FOXA3,CALU,XPOT,DNAJC10,EMC2,IGF1R,SMN1,DNAJC30,WASL,FCF1,AURKAIP1,CTDSP2,UBL4A,FURIN,SLC25A24,NDUFS3,TFRC,RB1,COX4I1,SRP14,SLAIN2,CDK9,TOP1,PRNP,GTF2E1,CSNK2A1,LAMTOR2,FAM20C,EMC4,DPP4,CALR,SNRNP70,POR,PSMA3,HADHA,SF3B1,HSPA8,P4HA2,NMRAL1,TMEM106B,DNAJC3,SNRPA,RNF41,HSCB,NPTN,TOMM22,WDR77,ARMCX3,MAP2K1,FOXS1,SEC61B,SF3B4,PRMT5,SNRPD2,ZMYM2,FOXP3,VDAC2,LMBR1L,NCKAP1,FBXO22,ATP5F1B,MLF2,SNRPB,CUL3,AUH,MYC,COX6B1,HSP90AA1,H2AZ2,COX8A,PSMA1,EMC8,EEF2,ZNF397,SOX2,MED9,E2F4,TOP3B,RBM12,RAF1,ZNF526,ATP6V1A,CORO1C,HSP90AB1,COX14,NDUFS8,UQCRH,SUMO2,LYAR,CTNNB1,NDUFV2,TMEM30A |
| 5.873e-08 | -16.65 | VPS45 (vacuolar protein sorting 45 homolog) | protein interactions | 11311 | 155 | 75 | 19454 | 5460 |
STYK1,RB1CC1,HNRNPD,CBL,TRAPPC2L,RHOG,DAG1,COPS5,LAMP3,FAM20C,RAB5C,ATG9A,LAMP2,CAV1,HSP90AB1,EGLN3,STX6,DIRAS3,RHOH,RAB1B,HNRNPL,ARF6,CAND1,VTI1B,RAC2,EED,GJA1,RAB35,HRAS,PTPN1,STX12,RAB4A,TFRC,EZH2,VPS33A,TMSB10,SNAP29,RIGI,RAB3B,KRAS,ARL5B,IGF1R,TMT1A,EHD4,STX8,NAPA,SCFD1,TRIM23,RHOB,LAMTOR1,STX16,RAB11A,VAMP5,RAB2A,ESR2,RHOJ,STX10,PTEN,VAMP3,UBE2M,FGFR1,VPS18,VPS4B,RPA2,CDC42,RND2,BET1,ATG16L1,STX7,NAPG,RAB9A,RAB5A,EP300,SLC39A9,RPA3 |
| 5.873e-08 | -16.65 | RNF185 (ring finger protein 185) | protein interactions | 91445 | 155 | 75 | 19454 | 5460 |
KRAS,PSMA5,HUWE1,COA1,SRPRB,TMEM33,RPS27A,TUSC3,PSMD12,SACM1L,TMEM147,RPN1,ZRANB2,PSMC3,RAD23B,UBL4A,FAF2,YIPF4,ERLIN2,DIPK1A,UBE2V1,LHFPL1,ARL6IP5,TNFSF18,MAPRE2,CGAS,TOMM70,TMPO,ERLIN1,ACSL4,FAM241B,UBE2D1,STYK1,ATG9A,MOV10,DNAJB2,TMEM19,UBE2E2,TMBIM6,RNF5,UBE2D3,UBE2K,PHB2,ATAD1,PXMP2,TMUB1,DVL2,APMAP,DERL1,RNF103,UBAC2,SIGMAR1,IDH2,HSP90B1,UBE2W,TMUB2,CFTR,UBB,LMBR1L,S1PR4,PSMA6,ATL1,EDNRA,PSMC5,SRP54,UBE2I,SGTA,ATP1B3,UBE2E3,TYROBP,ATP1A1,UBE2H,PSMA4,ARL6IP6,UFD1 |
| 5.896e-08 | -16.65 | POR (cytochrome p450 oxidoreductase) | protein interactions | 5447 | 212 | 96 | 19454 | 5460 |
LMAN1,TMPO,SPPL3,DERL2,PRNP,HSD17B11,RAC2,PTPN1,SRPRA,COMT,CYP2D6,POR,ESYT1,LAMTOR2,FAM20C,EMC4,ADIPOR2,SLC6A8,FKBP8,RIGI,RAB3B,FGF12,SRPRB,EMC2,TFRC,NDUFS3,CCDC47,VIRMA,UQCRC2,NRP1,SPOP,TUFM,HMOX2,DAD1,PDHB,SYVN1,DERL1,RTN4,RAB9A,CYP17A1,RARS1,CYC1,SSR1,UQCRC1,CDC42,ST7,NDUFS8,UQCRH,RHOH,CORO1C,ATP6V1A,CYB5A,CD63,PHB1,NDUFB8,RHOG,NDUFV2,XPO1,FAM241A,UBXN6,KRAS,EMC8,EWSR1,CYP2C9,TMT1A,CCR1,ITGB5,MOB3C,STIM1,RPN1,RAB4A,CHMP4C,PDHA1,DNAJC25,ISG15,EEF2,APEX1,ATP5F1B,STAT1,SEC61B,LMBR1L,CYB5R3,TOMM40,OST4,CUL3,PXMP2,EMC1,PHB2,RAB5A,PEBP1,CAV2,ARMCX3,RND2,OTULINL,SEC62,PGRMC1 |
| 5.944e-08 | -16.64 | PSME3 (proteasome activator subunit 3) | protein interactions | 10197 | 378 | 154 | 19454 | 5460 |
NDUFB5,PICK1,SREK1IP1,PSMA2,HNRNPF,PCGF3,PSMA1,PSMD12,UTP25,POLDIP3,AHCYL1,PCGF6,SPG21,ZNF526,SF3B5,RPS11,MOB3C,PSME2,PSMB4,PSMB5,BRD9,HNRNPL,CCAR2,HYPK,NDUFS8,EGLN3,DHX15,PSMD3,PFDN5,ZCCHC10,AGR2,MED4,LHX2,LCA5,DUSP9,FLYWCH2,RAB40AL,SF3B1,HSPA8,EP300,NUP50,DDX5,PSMA3,FXR2,SRSF2,COIL,SKP1,PSMB3,PRR13,RPP21,CDKN1A,PSMB7,MAP2K1,PIH1D1,AVPI1,VDAC2,FAM91A1,TRMT6,FAU,SNRPD2,GTF2F1,MATR3,ATP5F1B,PSMD4,TP53TG5,SSH3,DYNLL1,PSMB6,ERH,CREBBP,MYC,SFN,CUL3,KLHDC8A,PSMA4,PSMD1,BAG3,BRCA1,PSMD14,RPS26,HTRA2,PSME1,HAPSTR1,SNAPC3,DHX9,HSD17B10,SEM1,PSMA5,HUWE1,KPNA2,RASL10B,THRAP3,DUSP21,CAPZA1,RIGI,IMP3,STRBP,TP53,PSMB9,TAF1D,RPL15,TNFAIP8L1,TFCP2,MRPL36,RP9,MRPL51,CCDC69,CDR2L,PSMB1,ARL4D,FZR1,MIF,MRPL50,MDM2,PTP4A3,MOV10,CMSS1,RPA3,BAP1,SNAPC1,PML,ZKSCAN1,AMACR,CLK1,PIAS1,HSPA5,MRPL20,PSMC4,ATG16L1,SUMO1,FBXL19,CDC42,MRPS34,RPA2,WRAP53,ZCCHC17,SF3B6,CCNF,NUDT18,LIG3,PSMA6,PSMC5,UBE2I,ZMAT5,ADRM1,SMURF1,EAF2,VIRMA,RPL22,PSMB2,NTAQ1,FBXO7,PSMG3,UBE2H |
| 5.966e-08 | -16.63 | ADRB2 (adrenoceptor beta 2) | protein interactions | 154 | 340 | 141 | 19454 | 5460 |
SEC22B,CRYM,JKAMP,IDH2,HSP90B1,STOM,SNCG,IDH3A,GFM1,DLAT,PDHB,DAD1,HSPA5,TMUB1,RGS2,NPTX1,CSK,ATP5F1A,TUFM,RAP2C,ATP1B3,ATP1A1,OAT,AP2A1,UQCRC2,SEC61A1,RAB14,KCNJ3,UBB,SRC,GNAI2,TRAF1,VIRMA,FAM162A,EEF1A1,MAP1LC3B,TFRC,NHERF1,NDUFS3,GNAI3,ADRB3,SLC25A10,BACE1,ATP2B4,SLC25A11,RAB27A,PTGER1,PC,AKAP12,TSPAN7,HNRNPK,SRPRB,TMEM33,ARF4,UST,FKBP8,TMEM144,CD81,HDAC6,GNG2,GAPDH,ELOC,CD9,RAB3A,EEF1B2,GTF2B,AIFM1,TCTA,CD4,RGS10,PRNP,TOMM70,TMCC2,ILVBL,MDM2,PGRMC1,TSHR,IDH3B,YIPF5,MRPL12,ATP5PO,NDUFA5,SLC25A3,GNA14,ARRDC3,RNF5,IL1B,NDUFS2,ADRB2,PHB2,EEF1G,GNB4,RNF41,CUL2,CAV3,UFD1,LMNB1,RPS5,SERPINH1,GNG12,VDAC2,MOG,RAN,AP2M1,RGS5,ATP5F1B,TUBB,GPR37,GNB1,HSDL2,ETFB,ERLIN2,EEF2,RPN1,PDHA1,HGS,ADCY3,SLC25A5,GNA11,HSPD1,HNRNPA2B1,NDUFA4,ATP6V0B,ADRB1,PDIA6,HNRNPF,VDAC1,RAB18,HS2ST1,SYNJ2BP,PRDX1,VPS26A,ARHGAP5,PPP3CA,PHB1,ADGRG1,TSG101,PTGDS,RPLP1,MITF,EGLN3 |
| 6.037e-08 | -16.62 | MAPK6/MAPK4 signaling | REACTOME pathways | R-HSA-5687128 | 90 | 53 | 10285 | 3229 |
PSMB11,JUN,PSMC5,PSMB10,PSMA5,PSMA4,PSMB3,PSMA2,PSMB6,PSMB1,CDC42EP2,PSMD3,PSMB7,PSMC4,PSMA3,PSMB5,CDC42,PSMD14,TNRC6C,UBB,IGF2BP1,UBA52,PRKACB,CDK1,PSME1,RAG1,AGO1,PSMD10,PSMD7,MOV10,HSPB1,PSMA6,XPO1,PSMD1,PSMB2,PSMD12,MAPK4,PSMC1,MYC,SEPTIN7,PSMA1,PSMC3,PSMD4,CDC42EP3,RPS27A,MAPKAPK5,PSMD6,PAK2,PSMB4,PSME2,CCND3,PSMB9,SEM1 |
| 6.086e-08 | -16.61 | BET1 (Bet1 golgi vesicular membrane trafficking protein) | protein interactions | 10282 | 384 | 156 | 19454 | 5460 |
STX16,SLC30A5,NOP16,SERPINH1,SCFD1,CGRRF1,CYB561,FTSJ3,GCC1,SEC61B,RETREG3,CYB5R3,VDAC2,FAM91A1,MANSC1,REEP4,MB21D2,RAB6A,SEC62,OTULINL,PAFAH1B1,NOTCH2,PGRMC1,GOSR2,BET1,ASZ1,ATP5PO,VAPB,HADHA,BET1L,JAGN1,STX7,NOP53,STAU1,GOSR1,CYFIP2,WDR11,FAM174A,RAB5C,CLPX,AHSA1,STX1A,RHOG,STX5,NRSN1,GJA1,MRTO4,WDR6,NUP35,TMEM237,VAMP7,LYAR,RHOH,OCRL,EIF2S1,ERLIN2,ARFGEF1,TRMT1L,HGS,STX12,CRELD1,RPN1,RINT1,TMT1A,TMEM87A,SCYL2,TFG,POLDIP3,VAMP8,EPHA4,GORASP2,SEC13,VAMP5,SLC25A1,CALU,XPOT,NAPA,EPHA2,ARFGAP3,STX10,EIF2S2,TMEM74,CYBC1,ELOVL4,VAMP3,SEC63,BCCIP,TECR,SNX3,MGST3,CNP,CDC42,SEC22B,RABL3,LEMD3,CHRNB2,SLC12A2,GOLGA5,USE1,SSR1,LMNA,RAB9A,DERL1,ARFIP1,BANF1,TMX2,GRPEL1,USP8,NAPG,YKT6,LAMP3,HM13,RELL1,KARS1,AKAP8L,SLC2A1,SEC23A,RGP1,RAC2,HSD17B11,EHBP1,KRR1,SSMEM1,COX4I1,SRPRA,HACD3,STT3A,SURF6,CRB3,STX6,SLC38A2,LMAN1,ARF6,VTI1B,COG1,MARCHF4,UBIAD1,DDX39A,MRPL47,STRBP,SNAP29,TBK1,RBM34,TFRC,SNAP23,PTGES,STX18,MRPS18B,NKRF,SLC25A10,STX8,ARF4,SRPRB,TMEM33,HUWE1,SLC7A14 |
| 6.188e-08 | -16.60 | cellular response to organic cyclic compound | biological process | GO:0071407 | 464 | 190 | 18204 | 5365 |
FOLR1,NHERF1,HSP90B1,PDE2A,WBP2,PTGER1,NFKB1,DRD1,CGAS,GNA11,CFTR,CYP1B1,FKBP4,P2RY11,VPS54,CDK4,STC1,ACTB,ADIPOQ,SHMT1,MUL1,H2AZ1,ROCK2,IL10,HNRNPD,CRHBP,UBE2L3,ATP1A1,PAQR8,RAP1A,PDE12,PHB1,PPP1R1B,TOP2B,GABRB3,GNB1,RALB,NKX3-1,FBP1,ABHD2,SLC6A4,EGR1,FGF23,ALPL,MECP2,ESR2,NCSTN,EZH2,MLC1,NR2E1,RAN,CDKN1B,JUP,PQBP1,PGR,CYP7A1,SP1,SLC16A1,CCNA2,MDM2,TAF7,GNAI3,P2RY12,ITGA6,DDX5,PTGES3,P2RY1,MGARP,UGT1A1,TMEM38B,TRIP4,COMT,DAG1,SRC,CALY,HSPA8,GNG2,KLF4,TFPI,PHB2,PIK3CG,INSIG2,LEP,OR51E2,SMAD1,JAK2,STAT1,KDM1A,LRP6,RAMP3,ADCY2,EGLN2,GSK3A,GNA14,RAP1B,GRIA1,TADA3,CTNNA1,PAK2,SLC8A1,ATP1A2,AR,CYP1A1,MSN,NSG1,CALR,CTNNB1,GJB2,SLC1A1,VDR,GABRG2,NPR2,AANAT,SLC1A2,KCNMB1,P2RY4,GCLC,MIR182,FAM107A,GSTM2,AIFM1,DHX9,SPP1,DDIT4,FOLR2,HAND2,CST11,ADTRP,SULT1A3,DRD3,ITGA2,ELK1,SMYD3,RIGI,SIN3A,ADCY3,CAV1,IFNB1,RBFOX2,HTR1A,GPBAR1,MAVS,USP8,WNT10B,CIB2,MEF2C,EFNA5,MSTN,RUVBL2,PCK2,GABRB2,TLR9,PLCB1,IFIH1,RWDD1,MIR342,BRCA1,ATP1A3,MSX2,SELENON,MIR96,MIR21,ARL6IP5,MIR185,TLR3,RNF14,UBE3A,FBXO32,EIF4E,CREB1,IGF1R,SFRP1,BGLAP,GNAQ,PADI2,GNAO1,YWHAH,ATP5F1A,HTR2A,INPP5K,ERRFI1,CDK1,KLF9,SMAD5,IRF3,PPARA,FLOT1,OPRM1,RXRG,SLC1A3 |
| 6.273e-08 | -16.58 | IQCB1 (IQ motif containing B1) | protein interactions | 9657 | 274 | 118 | 19454 | 5460 |
RAB35,KCNA2,PSMB5,PSMB4,KRT8,SPINT2,EGLN3,PEG10,PRDX1,XPO1,YWHAH,EXOC1,GAS8,PEDS1,YWHAB,HSPB1,MRFAP1L1,HNRNPA2B1,EFNB1,TRIM21,PSMA1,GUK1,HNRNPF,PSMA2,CPLX1,RAF1,TUBA1A,TMEM59,SPG21,TUBB4B,CA14,VAMP2,PPID,PNMA2,GDI2,SESTD1,ANAPC2,ACTB,TUBB,DYNLL1,PSMB6,GRB10,PSMA4,CUL3,MRPL16,CKB,HSP90AA1,PFDN2,MDH1,SERPINH1,PEBP1,CXCR4,HSPA8,PSMA3,HADHA,OXCT1,ATP6V1G2,TRIM52,FTL,SKP1,PSMB3,PAFAH1B1,TANK,GPC4,STXBP1,NUDT3,PSMB7,SLC25A3,PDE9A,PSMB1,TRAK2,EIF2B5,PGAM1,HDAC6,GAPDH,MAP1B,LTBR,RAB1A,TMED1,PSMA5,SMN1,EEF1A1,UBE2V1,CTLA4,DTD1,CDIPT,TUBA1B,PSMA6,CAB39,TMEM74,RAB3C,ALB,RAB14,UBB,CEP97,PSMB2,TRIM32,CDC16,PTPN11,CSGALNACT2,EXOC5,ATP5F1A,CNNM4,XPOT,ATP1A1,PEA15,MAPRE1,CALU,BAP1,RPA3,MNS1,PGK1,UBE2K,LDOC1,HSPA5,DDAH1,HSP90B1,TMOD1 |
| 6.359e-08 | -16.57 | cellular response to nitrogen compound | biological process | GO:1901699 | 580 | 230 | 18204 | 5365 |
SLC2A8,MIR106B,YWHAG,TLR3,MIR200A,EPHA4,SOS2,DEFB124,LY6H,CHRM4,SFRP1,IGF1R,CSK,AHCYL1,MIR107,BGLAP,GNAQ,GNAO1,SOCS2,AKT2,ATP5F1A,INPP5K,HTR2A,CA2,CHRM5,IRF3,CDK5R1,OPRM1,FLOT1,SLC1A3,ACHE,RIGI,SIN3A,PAX6,IFNB1,CAV1,HTR1A,MAVS,WNT10B,EDNRA,CD36,CIB2,MEF2C,LDOC1,STAMBPL1,CAV3,PLCB1,TLR9,PCK2,GABRB2,IFIH1,GNRHR2,RGS10,BRCA1,JAK1,ATP1A3,SELENON,IDE,MIR146A,PSEN1,DPEP1,IGF1,EP300,UCP2,PIK3R3,NSG1,SESN3,CTNNB1,GH1,SLC1A1,GJB2,NPR2,GABRG2,MAP1B,AGTRAP,SLC1A2,AANAT,GPT,GCLC,P2RY4,PTPN22,TBC1D4,AKT1,AIFM1,GSTM2,DHX9,RTF2,STAT6,FOLR2,TLR6,DDI1,SULT1A3,ADRB2,DRD3,SELENOS,GRB10,ATP2B4,BCL2L1,CHRM1,JAK2,EIF4EBP2,STAT1,PCSK9,KDM1A,CAV2,PRKCB,HDAC5,GNA14,GSK3A,SHC1,CRHR1,RAP1B,XBP1,GRIA1,CPEB1,CTNNA1,SOX9,GNAI2,RAB13,SLC8A1,NCOA5,CRKL,PIK3CA,MDM2,GNAI3,ICAM1,TP53,P2RY12,HPCA,GPR173,CAMP,MIR143,P2RY1,TSHR,MGARP,TMEM38B,CSH1,COMT,LARGE1,PTPN1,GHR,CALY,SRC,GNG2,KLF4,BACE1,MIR140,PIK3CG,INSIG2,TLR4,LEP,NR4A2,NSMCE3,NFE2L2,SLC6A4,EGR1,MECP2,NCSTN,CHRNA7,CHRNB2,EZH2,PIK3R1,KLHL22,GAB1,PIK3R2,PQBP1,JUP,SESN2,AMIGO1,CHMP5,SP1,PPARG,CCNA2,SHOC2,RPL23,STC1,CYP11B2,ACTB,SHMT1,TNF,ADIPOQ,RAF1,ROCK2,MUL1,HRH3,HNRNPD,CRHBP,RAP1A,TRAF2,MIR145,PDE12,PPP1R1B,TOP2B,GABRB3,GNB1,RALB,CDK5,MIR98,FCGR2B,CXCR4,FBP1,AGER,HRAS,FOLR1,NPPC,NHERF1,VAMP2,FOS,HSP90B1,PDE2A,CASP4,PTGER1,CHRM3,NFKB1,DRD1,RAB31,GUCY1B1,SLC22A12,CYP11B1,CGAS,RB1,GNA11,CFTR,GJA1,RARRES2,CASTOR2,CYP1B1,P2RY11,FOXC2,STAT5A |
| 6.373e-08 | -16.57 | CDCA3 (cell division cycle associated 3) | protein interactions | 83461 | 174 | 82 | 19454 | 5460 |
NTRK2,IGF1R,DDR1,TMT1A,SFXN1,ARF4,FLOT1,FKBP8,KRAS,RAB3B,TRAF2,CTDSP2,MTCH2,RND3,CDK5R1,CCR1,STIM1,RAB4A,PTRH2,GJA1,AIFM1,RAB35,HRAS,COX4I1,EPHB6,DIRAS3,STX6,TMPO,PLGRKT,SLC25A12,CAV1,COX14,ARF6,FZR1,RHOH,LAMP3,ATG9A,LAMP2,RAB5C,STYK1,RHOG,ESYT1,SYVN1,TMEM185A,RAB5A,AKAP1,RAB9A,MAVS,DERL1,RHOU,TOMM20,STX7,SKP1,CERS2,SLC25A51,CDC42,SEC62,TIMM29,ST7,TOMM22,ATP6V1C1,ATG16L1,GTF2H5,ARL15,CTDSP1,FGFR1,RMDN3,SEC61B,TRAF1,APEX1,MGST3,RHOJ,DNAJC5,BAG3,RAB2A,RAB11A,NTRK3,NRP1,FIS1,CHORDC1,LAMTOR1,RHOB |
| 6.377e-08 | -16.57 | LPAR1 (lysophosphatidic acid receptor 1) | protein interactions | 1902 | 204 | 93 | 19454 | 5460 |
REEP6,SYP,SNX14,ARL6IP6,CSGALNACT2,ACP2,CD47,SC5D,ADGRL3,SCAMP2,SELENOT,PIGW,LEMD3,TM9SF1,STOM,GOLGA5,HACD2,CERS2,TESC,ADGRE2,FITM2,TMEM11,MSMO1,NOP9,EXTL2,DERL2,TNFSF18,ARL6IP5,STARD3NL,SLC39A10,ARL10,TSPAN3,GNAI3,RNF121,CTLA4,ZMYM3,ALG11,TMEM126A,ATP5PB,LPCAT3,EMC2,ATP2B4,STX8,SLC30A5,TM9SF4,KDSR,REEP4,LGALS3,B4GALT3,LRRC8A,GPR89A,SLC30A7,RETREG3,SERINC1,PIGK,GAMT,FAM8A1,SIGMAR1,SEC62,GOSR2,SLC19A2,GJC1,CERS6,ZDHHC17,STX7,CMTM6,SLC35F2,MIA2,TAPBP,TSPAN15,TMEM106B,CXCR4,TMEM164,FAM241B,FAM241A,FAM20B,EMC6,RMND1,PEX13,STX5,MFSD5,GPR137,CRELD1,ENPP4,VAMP2,PCDH19,SACM1L,PGAP4,EMC8,KRAS,NDUFB5,GPAA1,TMEM87A |
| 6.412e-08 | -16.56 | GNL2 (G protein nucleolar 2) | protein interactions | 29889 | 352 | 145 | 19454 | 5460 |
TP53,STRBP,RPL15,AURKAIP1,WBP11,RBM34,CDK8,RP9,SRP72,HBP1,SNIP1,RPL3,RPL23A,H3C1,ADD2,RPL17,MRPS18C,FAM133B,SPATS2L,MPG,CHCHD1,SNRNP70,TUBG1,NOL12,RPS2,KRR1,MRPS9,SRP14,CAND1,RPS16,FZR1,MRPS23,CDC5L,SURF6,ZBTB2,DKC1,RBM42,FGF13,CDK7,SNRNP27,ZCCHC17,MRPS34,LMNA,RPA2,RPL26L1,RPLP0,SIRT7,NLE1,RPA3,SNAPC1,DDX46,MTDH,RNF113A,RPL4,NPM3,DGCR8,RPL7A,DNAJC8,USP14,RPL26,RC3H2,MECP2,UBE2H,ZNF330,EIF2AK2,METAP2,PSPC1,RPS3,POLR3H,FGFBP1,PRKRA,RPL13A,SRPK2,RPL22,RPP25,SMURF1,DHX38,RAF1,H1-3,RPL18,FGF3,PPAN,RPL31,RPS24,SRSF7,HMGN4,DHX16,G3BP1,H1-6,KRAS,SRSF4,MRPS17,WWP2,MRPS35,IFI16,DDRGK1,XPO1,SKIC8,DDX23,DICER1,LHX2,DRG1,MPHOSPH6,RSBN1L,MRPS26,MRTO4,PHB1,SRSF1,RPL8,LYAR,ISG20L2,NOB1,RPS10,SYK,MFAP1,NKAPD1,C1D,NOP53,STAU1,UFL1,G3BP2,MRPS7,MYC,RBM15B,ZNF668,DCAF4,RBM27,MRPS25,MYO6,DNAJB6,RIT1,H1-1,NSA2,GTF2F1,RPS9,GTF2F2,RPL37A,FBXO22,RPL35,SNRNP40,RANBP6,RPL19,RPL10,PRRC2A,APEX1 |
| 6.481e-08 | -16.55 | FCERI mediated NF-kB activation | REACTOME pathways | R-HSA-2871837 | 79 | 48 | 10285 | 3229 |
SEM1,PSMB9,PSME2,UBE2D1,IKBKB,PSMB4,TRAF6,PSMD6,RPS27A,PSMD4,PSMC3,PSMA1,PSMC1,UBE2N,PSMD12,BCL10,TAB2,PSMD1,PSMB2,PSMA6,UBE2V1,NFKBIA,PSMD7,PSMD10,PSME1,SKP1,UBA52,UBB,RASGRP2,PRKCQ,PSMD14,TAB1,PSMA3,PSMB5,PSMC4,PSMB7,PSMD3,PSMB1,PSMA2,PSMB6,FBXW11,PSMB3,PSMA4,NFKB1,PSMA5,PSMB10,PSMC5,PSMB11 |
| 6.518e-08 | -16.55 | PFAS (phosphoribosylformylglycinamidine synthase) | protein interactions | 5198 | 150 | 73 | 19454 | 5460 |
MOV10,GTF2E1,ATG7,COPS5,TRAF6,PDCD10,DCAF11,DNAJC7,DFFA,TFE3,SERPINC1,PRNP,EGLN3,ZNF593,G6PD,TOP3B,KBTBD4,TP53,EEF2,BZW2,VAC14,PABPC1,PC,EMC2,KRAS,SEPHS1,MYC,CUL3,CIAO1,LDHB,USP14,CKB,SPOP,LAMTOR1,CCDC22,ATG3,FBXW11,YWHAZ,UBE2H,RIT1,OPTN,GSK3A,SGTA,MSN,EIF4H,MTM1,SSH3,PPAT,TUBB,ACTB,MAT2B,FERMT2,RABIF,VIRMA,APEX1,ATG16L1,CAPN1,GTF3C4,DET1,RPA2,PAK2,ISOC1,ACACA,PIH1D1,RPA3,BAP1,SIRT7,HSPA8,RAB5A,PRDX6,STAU1,DUSP26,GINS3 |
| 6.616e-08 | -16.53 | protein modification by small protein conjugation | biological process | GO:0032446 | 695 | 269 | 18204 | 5365 |
KLHL7,DCAF4,TRIM68,BRAP,CDC16,UBE2E2,UBE2K,WWP2,UBE3A,RNF14,RCHY1,FBXO11,COPS7A,TRAF3IP2,KBTBD13,FBXO32,ANAPC4,FZR1,CDC20,SOCS2,UBB,RNF122,HECTD3,TRIM34,COPS2,SHPRH,HERC3,PELI3,MARCHF5,SOCS4,WSB1,MED21,RNF181,NEUROD2,PELI1,RNF34,TRAF7,KLHL25,UBE2A,URM1,SOCS3,IFI27,TRIM11,TNKS,NEURL2,RC3H2,NMI,VPS18,RNF7,CBFB,MED27,FBXO25,USP5,ATG7,IFIH1,KLHL3,SPOP,UBA3,SOCS5,SMURF1,WWP1,ZBTB16,TRIM54,UBE2B,BRCA1,COPS4,KLHL24,UBE2I,ANAPC2,RNF113A,UBE2S,TRIM26,EGR2,TNKS2,RNF103,UBE2W,DCAF11,FEM1C,PPP1R11,RNF39,UCHL3,KLHL12,NEDD8,FBXO9,WDR77,RLIM,KLHL15,TNFAIP3,CTNNB1,RING1,RNF11,RNF208,TRIM8,UBE2V1,KBTBD2,TRIM37,MSL2,UBE2V2,HERC4,UBE2G2,DCAF16,AKT1,FEM1B,SIAH2,RNF128,ISG15,MARCHF3,RPS27A,RNF8,UBA52,UBE2F,RNF167,ASB3,MARCHF9,E4F1,MED31,ZBED1,CAND1,ANAPC11,OS9,PRPF19,CDK5RAP3,SYVN1,COPS5,SUMO1,RNF126,CTU1,TRIM22,PCMTD1,SPSB1,CBL,TOPORS,UBE2M,SKP1,TRIM63,UBE2N,TRIM24,UBE2D1,MARCHF4,DCAF5,WDSUB1,CDC26,FBXL3,RNF146,MDM2,DTL,SPOPL,VCPIP1,CDC23,ZC4H2,SUMO3,MED17,RNF121,ZNF451,TRIM45,ANAPC16,SENP5,UBE2D3,ASB11,SUMO2,G2E3,TRIM35,ENC1,CBLL1,HUWE1,CRBN,ANKIB1,FBXO30,TRIM21,FBXL7,RNF41,TRIM27,RAB40AL,DET1,CUL2,RNF139,NSMCE3,FBXO7,NFE2L2,UBE2H,RBCK1,SIAH1,TRIM15,TRIM44,FBXO22,RNF115,SPSB3,CCAR1,RNF20,NQO1,ZNRF1,HECTD1,UBR7,CDCA3,TRIM10,KLHL22,COP1,CUL3,TRIM52,ASB7,RNF187,TRIM3,ASB8,UFL1,AREL1,NBN,DDRGK1,NT5C2,DCUN1D5,APPBP2,KCTD10,MUL1,CDK8,TRIM32,TRAF1,UBE2L3,FBXO31,TRAF2,TRIM62,IRF2BP1,KBTBD6,ASB1,ELOC,BIRC2,TRIM6,STUB1,KCTD11,FEM1A,BFAR,KLHL9,MED10,CISH,OTULIN,ANAPC13,STX1A,MED30,FBXW7,MED11,RNF182,HDAC6,HECW1,RNF5,TRIM5,IRF2BPL,DCUN1D1,UBE2E3,PML,ATG3,DCUN1D3,RNF152,RAG1,FBXW11,TNFAIP1,TRIM23,RNF141,RNF144B,CCNF,MYLIP,TRAF6,NDP,KCTD9,NAE1,RNF10,PIAS1,RNF26,UFM1,RNF40,FBXO3,RNF133 |
| 6.684e-08 | -16.52 | positive regulation of cell migration | biological process | GO:0030335 | 592 | 234 | 18204 | 5365 |
STAT5A,MIEN1,FOXC2,CCR2,AIF1,CCL19,ARF6,CLDN3,CYP1B1,ACVR1,MIR222,CCL25,RARRES2,MIR181D,PRKCA,CCL4L1,PLP1,DRD1,TERT,CCL18,TMSB4X,CCL2,CXCL10,TNFRSF14,RHOB,PLG,MIR23A,PYCARD,HRAS,ZNF304,GFUS,CREB3,AGER,HDAC6,ELP3,CXCR4,TBC1D24,CD40,CCL23,ACVR1B,CLDN4,EPHA2,CXCL12,MAPRE2,FGF7,HMGB1,FGF16,SELENOK,RAB11A,MED23,MIR145,CX3CR1,TRIM32,ROCK2,XCL1,SMAD3,CX3CL1,MIR101-1,VSIR,TNF,DDRGK1,F10,MIR30A,FZD4,SP1,MIR296,NTRK3,CXCL13,CCL1,AAMP,RHOJ,MIR711,GPNMB,PIK3R1,GAB1,CCAR1,MIR29A,SEMA7A,VEGFA,IL23A,BMPR2,IL34,NFE2L2,LGALS3,TLR4,THY1,MIR939,PIK3CG,CCL8,MIR590,CCL11,CBLL1,ARHGEF39,ANGPT1,ZNF609,SRC,RAC2,FGFR1,ITGAV,ACKR3,MIR143,SOD2,MIR135B,CLEC7A,MAP3K3,ITGA6,P2RY12,TNFAIP6,IFNG,MADCAM1,RRAS2,ICAM1,STK4,F7,CD47,TIAM1,LPAR1,MDM2,CXCL8,ARHGAP5,SDCBP,CRKL,TGFBR2,PLAA,MIR221,SNAI2,GNAI2,KIT,SOX9,MET,MIR20A,CCL21,XBP1,TWIST2,MIR10B,MIR448,CCR1,PRKCE,TIRAP,NRP1,ACTN4,FGF1,JAK2,CD151,ATP8A1,ITGA2,SEMA3C,TNFSF18,PROX1,CCL20,CCR7,CDH13,CCR6,SEMA5A,IL1B,AKT1,FAM107A,PPP3CA,WNT7A,MIR182,CCL24,ADAMTS1,TCAF2,ATP5F1B,FGF10,CALR,PIK3R3,MAP2K3,IL1A,TGFB2,PDCD10,ACTA2,IGF1,MIR146A,MIR519D,PTN,HBEGF,MIR21,FGFBP1,S100A11,CLDN1,SEMA4C,ELP6,UBE2I,MIR31,CD99L2,GLIPR2,IL4,MIR342,TACR1,HSPA5,RTN4,MIR208A,MSTN,NUS1,MIR150,SWAP70,MIR210,CAV1,PAX6,DAPK3,VEGFC,EMC10,IQSEC1,MIR10A,OXSR1,CSF2,FUT1,CD274,FAM89B,IL12A,AKT3,MIR132,CCL3,ATP5F1A,AKT2,HSPB1,SEMA6C,CDC42,MMP9,MIR126,IGF1R,IL6,FERMT2,CCL17,MMP14,FGR,AKAP12,DEFB124,EPHA4,MIR200A,GPSM3,CCL5,FOXP1 |
| 6.692e-08 | -16.52 | PEX19 (peroxisomal biogenesis factor 19) | protein interactions | 5824 | 185 | 86 | 19454 | 5460 |
FAS,SMAD2,FIS1,DLG4,SELENOT,RMDN3,PSMD6,F11R,DYRK1A,ABHD12,CHST7,ATG16L1,BORCS6,UBAC2,RDH12,CYC1,IRF3,ATP5MK,EXD2,CD40,BAP1,TMX2,NUBP2,AKAP1,RAB9A,GRPR,OIP5,SLC25A51,EIF1B,MRPL20,FBXO30,PEX26,PXMP2,TOMM20,HIGD2A,PMP22,MARCHF5,FAR2,FAM174A,CENPP,CMSS1,QPCTL,FAM20B,PPIB,XPO1,MUL1,IFNB1,HSPB1,HAX1,PEX3,PSMB4,CD274,HACD3,PSMB1,EXT1,MFSD5,DSTN,HSD17B11,PEX13,SELENON,STK3,DIRAS3,SLC25A17,UQCRH,COMTD1,DCAKD,HINT3,FAF2,MTARC2,ASPM,PSORS1C2,CA14,SIGLECL1,GLE1,GLCE,COX8A,SEMA4C,PGAP4,PTPN4,PSMA5,IL23A,RIGI,GALNT2,HS2ST1,TUSC3,GSKIP |
| 6.739e-08 | -16.51 | TRMT61B (tRNA methyltransferase 61B) | protein interactions | 55006 | 280 | 120 | 19454 | 5460 |
MRPL23,ATP5F1B,MRPL13,TRMT11,DLST,MTG1,TACO1,MRPS25,AK3,PYCR1,CUL3,PMPCA,AUH,FMC1,MRPS7,OXCT1,NDUFS2,RTKN,ATPAF2,NDUFA5,PDP2,ACAA2,CTBP1,MRPS18A,ATP5PO,MRPL12,TIMM13,PRDX3,IDH3B,ASB8,NDUFS8,GATD3,NXT1,PPP2CB,MRPS26,RHOG,MRPL18,NDUFV2,MRPL9,MRPS35,MTRF1,CLPX,KGD4,ATP5F1D,ETFA,KRAS,MRPS11,COX8A,HINT2,THNSL1,PREPL,HSPD1,NDUFA12,PDHA1,PNMA2,NDUFS6,ETFB,HSDL2,DYRK1A,ACAT1,MRPS28,FBLN5,MRPL53,PPTC7,MRPS16,TUFM,PYCR2,NDUFAF2,MRPL20,POLDIP2,MRPL40,MRPL41,NME4,IRF7,GFM1,SQSTM1,DLAT,TRIM10,MTRES1,HEXIM1,HIKESHI,QRSL1,MRPS34,SPRYD4,MRPL10,MRPL24,MRPS23,MALSU1,ATP5PD,DBT,MRPL50,MGME1,COX4I1,SSBP1,MRPS9,TRMT5,LYPLAL1,GRSF1,ABHD10,MRPL22,FASTKD5,HNRNPK,HSPE1,MRPS33,PDE12,HSD17B10,THG1L,MRPS18B,ATP5PF,EIF1AD,ACADSB,NDUFS3,BCS1L,METTL15,GLRX5,PPIF,MRPL11,MRPL47,NDUFA2,ATP5PB |
| 6.785e-08 | -16.51 | TCP1 (t-complex 1) | protein interactions | 6950 | 519 | 201 | 19454 | 5460 |
STAU1,UFL1,DDX5,HSPA8,HDAC5,DDX39B,PACRG,PIH1D1,PPT1,UBL3,ESR2,APEX1,SNRNP40,COP1,PSMD14,CCT2,PLA2G15,PSMA4,KLHDC8A,MYC,APOBEC3B,KRAS,ACTR1B,CDK5,CCT8,PABPC1,CTTNBP2,PLS3,DCAF8L2,TUBB4B,SOX2,TUBA1A,ISG15,HEXA,HSP90AB1,CCT7,SUMO2,DYNC1I2,WDR82,CCDC71,POU5F1,AGR2,DCAF5,CTNNB1,ACTR3B,DDRGK1,DCAF4L2,IFI16,MAPK4,HDAC3,DERL1,HCFC2,BAP1,HEXIM1,UBE2M,SSR1,SAMM50,RPA2,WRAP53,TRIM68,CDC20,SMURF1,KCTD9,BUB3,MAP3K3,MOB4,CREB1,RPS3,UQCRC2,UBE2H,ATP1A1,DTL,RC3H2,RAP2C,AKT1,SLC25A1,STRADB,MEPCE,RASL10B,KDM4B,DYNC1I1,POC1B,PSME1,METTL18,MAP1B,TFCP2,RPAP2,ACTR1A,RPSA,TP53,KBTBD4,CDC5L,TMPO,TUBG1,B9D1,COPS5,FAM20C,PPP2R2C,CRY1,FBXW4,THOC3,PPARG,TOR1AIP2,ACTL6A,WDR77,ALKBH3,GNB1,GPR37,TUBB,ACTB,PRDX2,ILK,RIT1,HSP90AA1,DCAF4,BRCA1,CUL3,ACO2,SAR1B,PCGF6,TRIM37,RBBP7,G3BP1,HECTD3,TRIP4,POLR2C,NME1,EZH2,RPN1,WDR37,ERLIN2,E2F4,RAF1,B3GNT2,CETN2,PPIA,EGLN3,MAP1LC3A,IGBP1,PHB1,PPP2CB,TRAF3IP3,FOLR1,DCAF11,SKIC8,GABARAP,PIAS1,FBXW7,IRF7,GTF2I,SQSTM1,PRPF4,RPA3,DVL2,PDCL,METTL14,CDK1,WDR83,WDR5B,ATG16L1,VIRMA,SH3BP4,ARMC6,YES1,ABHD17A,NDN,PTEN,RPS20,UBASH3B,GANAB,ZBTB18,PPM1M,SMAP2,TUBA1B,CCNF,CDC73,STK24,AR,FBXO7,CIAO1,FBXO25,DNAAF10,HUWE1,HAPSTR1,FAF1,RNF181,PPP4C,MMACHC,ACTR2,MAP1LC3B,CCT5,ZBTB2,EEF1AKMT3,SMAD3,EFNA3,FGR,CRBN,SUV39H1,HDAC6,EMC4,FNDC11 |
| 6.913e-08 | -16.49 | regulation of protein stability | biological process | GO:0031647 | 326 | 141 | 18204 | 5365 |
HSP90AA1,UTP25,ZBED3,PRNP,PHB2,STK3,DAD1,DNAAF10,TRIM21,FLOT1,PTGES3,PPIB,HSPA8,HSPD1,SRC,BAG2,PRKRA,GPIHBP1,LAMP2,CREB1,ATP1B3,USP2,CRYAB,CAMLG,ZSWIM7,GNAQ,MDM2,TMEM183A,ZNF207,RPAP3,FBXL3,TP53,MOSMO,EPHA4,STK4,CCT5,TOMM7,TCP1,RPL23,CD81,CDC73,HDAC3,CUL3,RTN4,KLF1,CDC37L1,PIK3R1,UBE2B,CREBL2,YWHAZ,STX12,HSP90AB1,PIM2,CTSA,CDKN2AIP,RUVBL2,NF2,HYPK,FBXO7,TYROBP,PFDN6,PYURF,RNF139,USP8,APTX,WNT10B,TRIM44,NDC80,GAPDH,GOLGA7,RPS7,DPM2,TESC,HDAC6,RNF5,FBXW7,RNF128,CCAR2,DDI1,MCM8,CCT8,CREBBP,PYCARD,CCT7,PDRG1,STUB1,FAM107A,CLU,TRIM37,CMTM6,LMNA,USP13,RABL3,NAPG,SAV1,UBL4A,NOP53,MSX1,CRTAP,TAF9,PHB1,RUVBL1,MT3,TF,PDCD10,NAA15,IGF1,EP300,DDRGK1,CALR,MUL1,NAA16,CHP1,MIR101-1,SMAD3,ATP1B1,H1-5,CDK7,TRIM24,CCNH,TADA3,CTNND1,CSNK2A1,DNLZ,MYLIP,BAG3,TMEM88,PIH1D1,TERT,FBXW11,SYVN1,DERL1,QRSL1,P3H1,SUMO1,PTEN,STXBP1,CCT2,PFDN2,SH3GLB1,TTI2 |
| 6.914e-08 | -16.49 | TSFM (Ts translation elongation factor, mitochondrial) | protein interactions | 10102 | 367 | 150 | 19454 | 5460 |
NDUFA5,UBAC2,MRPS18A,CPLX2,ATP5PO,NDUFAF3,MRPL12,PRDX3,ACTL6A,MRPS7,PHB2,OXCT1,NDUFS2,HSCB,HADHA,ATP5IF1,HSPA8,NGRN,DNAJB6,MRPS25,CYP1A1,AK3,MRPL16,MRM2,HNRNPAB,PYCR1,PMPCA,GFUS,ACO2,MTG2,AUH,CLIC4,APEX1,NDUFAF4,ATP5F1B,MRPL23,MRPL13,MTG1,DLST,TACO1,NDUFA12,NDUFS6,PDHA1,NUDT19,GTF2E2,ETFB,RAF1,HSDL2,HNRNPDL,MRPS17,ETFA,ATP5F1D,KGD4,MRPS11,COX8A,HINT2,THNSL1,HSPD1,PREPL,MRPS26,MRPL18,GAS8,NDUFV2,MRPL9,STOML2,MRPS35,HMGA1,MDFI,MTRF1,DDX50,CLPX,WIF1,PPIA,NDUFS8,PNPLA8,HNRNPL,FAHD1,GATD3,PHB1,MTRES1,RPA2,MRPS34,QRSL1,MRPL10,CDC42,NDUFAB1,MRPL20,POLDIP2,GRPEL1,OGDHL,MRPL41,MRPL40,PDHB,NME4,MRPL17,DLAT,GFM1,TWNK,IDH3A,RPA3,OAT,MRPS16,TUFM,CEP70,PYCR2,NDUFAF2,ACAT1,MRPS28,MRPL53,MRPL49,MRPL51,NDUFS3,ACOT13,ACADSB,METTL15,BCS1L,HADH,PPIF,MRPL47,NDUFA2,ATP5PB,MRPS18C,MRPL22,FASTKD5,HSPE1,PDE12,MRPS33,REXO2,THG1L,HSD17B10,MRPS18B,ATP5PF,MRPL52,TRMT5,SLC2A1,LYPLAL1,COX5A,GRSF1,MRPL24,MRPS23,ATP5PD,DBT,MALSU1,MRPL50,MGME1,COX4I1,ARMC1,ALYREF,MRPS9,SDHB |
| 7.038e-08 | -16.47 | regulation of response to biotic stimulus | biological process | GO:0002831 | 534 | 214 | 18204 | 5365 |
LYPLAL1,TAX1BP1,CD36,POLR3F,OPTN,NMI,CLEC6A,MAVS,TAB1,SERPINB9,CPTP,CAV1,IFNB1,TRIM11,TYROBP,RIGI,SIN3A,LYAR,MIR146A,MIR21,SFN,LILRA2,MIR149,APOBEC3F,SH2D1A,MYD88,GFI1,ZMPSTE24,RTN4,IFIH1,TLR9,IFNK,APOBEC3G,DAPK1,PYDC2,RSAD2,TRAF3IP2,USP38,LRRC14,IL12B,POLR3B,FGR,UBE2K,TLR3,CCL5,FOXP1,FLOT1,PELI1,RNF34,HSP90AA1,USP15,IRF3,LILRB1,ELMOD2,MATR3,FOXP3,IL12A,CD274,HSPD1,BCL10,MIF,OAS1,TRAF3IP3,CCDC92,DEFB114,PRKCE,LACC1,TIRAP,MIR708,PLA2G5,STAT1,NR1H2,IRF7,TLR7,NLRP6,MIR200C,BANF1,KLRD1,PAK2,IFI35,BECN1,STAT2,FAM3A,EIF2AK2,CD14,MIR20A,TRIM22,KLK5,TNFAIP3,CLPB,FCN2,EP300,NFKBIA,HCFC2,CREBBP,TLR6,KLK3,ISG15,NCR3,IL1B,NOP53,DHX9,TRAFD1,AKT1,PTPN22,RNF115,SAMHD1,ATAT1,IL23A,YTHDF2,TRIM15,CNOT7,TRIM44,PPM1B,IKBKB,IL15,NFE2L2,TICAM1,TLR1,BPIFB1,CSNK1A1,SLC15A2,PPARG,IFI16,TLR8,YWHAZ,IRAK4,TRIM3,IRF1,PQBP1,UFD1,PIK3R1,ZNRF1,LGR4,NEK7,CLEC7A,IL21,IL17F,SQSTM1,LEP,TLR4,MIR140,TRIM21,NONO,NECTIN2,SEC14L1,PTPN11,FGL2,MICB,PHB2,TOMM70,HEXIM1,HSPA8,SRC,PTPN1,MIR26B,PRDX2,CGAS,KCNJ8,ARG2,LSM14A,PSPC1,TASL,MAP2K6,TMEM126A,MAPKAPK3,NINJ1,XRCC5,TRIB1,TBK1,RNF26,PLSCR1,TIFA,IRF4,TLR5,TICAM2,TLR10,NLRP3,TRAF6,EIF4E2,TLR2,MIR17,CLEC12B,PRKCA,LY96,SELENOK,TRIM6,LACRT,BIRC2,PHB1,TRIM62,PIK3AP1,KLRC2,TRIM32,MUL1,CX3CL1,SARM1,TNF,NT5C2,DUSP10,CD226,TRIM5,PYCARD,FCGR2B,S100A8,EMILIN1,NFKBIL1,OTULIN,ABHD17A,MBL2,NLRP1,HMGB1,CD1D,SYK |
| 7.096e-08 | -16.46 | CDKN1A (cyclin dependent kinase inhibitor 1A) | protein interactions | 1026 | 373 | 152 | 19454 | 5460 |
RPS4X,ZBTB16,FHL3,TRIM21,PCNA,CDK5,HNRNPA2B1,GADD45A,KLHL23,HSPD1,AKT2,RNF126,RPL18,NTN4,HDAC11,JUN,CRTC2,TUBA1A,E2F4,VDR,CKS1B,CCT7,MITF,SUMO3,RNF144B,ATP6V1A,TSG101,S100A8,FBXO32,MGMT,DCAF11,CDKN1B,UBE2D1,ACTL6B,PPFIBP1,CCND3,SKP1,CMTM6,YTHDF1,EP300,DDX5,PSMA3,HSPA8,MED31,CKS2,PCLAF,CDKN1A,H1-5,APEX1,LRIF1,GADD45G,RBBP4,RPL35,FBXO22,TUBB,ACTB,ATP5F1B,RPS9,CDC7,KRTAP3-1,BAD,GNG12,EIF4EBP3,HSP90AA1,SP1,GADD45B,TFDP2,CCDC85B,CUL2,RUSC2,MYC,NFYA,CREBBP,TNKS2,HNRNPK,DYNC1I1,CELF6,CPNE2,SLC25A11,FAF1,RAB1A,TBC1D4,NFE2L2,EEF1A1,TP53,CDK4,CDC5L,MDM2,TOP1,RPS16,PPP1R18,FZR1,TNKS,RB1,CDK6,SMAD3,EEF1B2,RPS2,ESYT1,SMAD4,MED21,GAPDH,PPM1D,CXCL13,HDAC6,CSNK2A1,TLE1,NFKB1,FNDC11,HSPA5,SS18,ADAMTS10,PDHB,KDM1A,TRIM3,POLD2,TFIP11,CZIB,CDK1,CCNA2,CCND1,ING5,CCN3,RPS14,TRAF1,DDAH2,BCCIP,CDC20,UBB,NR1H2,CTSB,TRIM54,DAPK3,TXN,ZBTB17,CSNK2B,PSMC5,TRIM27,TMSB4X,OPTN,FKBPL,STUB1,INPP5K,IGF2BP1,DTL,PHKA1,GMNN,BRAP,CCNB1,AKT1,SPRED1,TAF5L |
| 7.173e-08 | -16.45 | small ribosomal subunit | cellular component | GO:0015935 | 77 | 45 | 19108 | 5553 |
RPS20,CHCHD1,RPS14,RPSA,RPS16,MRPS16,MRPS21,RPS12,RPS27L,EIF2D,RPS10,RPS23,RPS28,MRPS35,UBA52,RPS4X,RPS2,MRPS26,MRPS7,RPS7,RPS26,IMP3,MRPS11,MRPS17,FAU,RPS29,MRPS9,RPS11,RPS24,RPS13,RPS17,MRPS23,MRPS33,MRPS18C,MRPS28,RPS15,RPS5,MRPS18B,RPS3,RPS9,MRPS25,MRPS18A,MRPS34,RPS27A,AURKAIP1 |
| 7.198e-08 | -16.45 | PSMB6 (proteasome 20S subunit beta 6) | protein interactions | 5694 | 235 | 104 | 19454 | 5460 |
MOB3C,EZH2,TUBA1A,ISG15,NAA15,B3GNT2,RAF1,ERRFI1,RPS27A,PSMD12,PSMA1,KRAS,PSMA2,RBBP7,RPAP3,RUVBL2,MRPS11,UBE3A,CCT8,ELP6,AGR2,PSMD10,CTNNB1,PRPF19,PSMD3,DYNC1I2,SPTAN1,PSME2,PSMB5,PPP2CB,PSMB4,CAV2,PSMB7,MAP2K1,PSMB3,DDI1,PSMC1,SKP1,HSPA8,PSMA3,RIT1,COX16,POMP,PSMD14,PSMD1,CPSF2,MYC,PSMA4,PSMB6,ESR2,PSMD4,PSMD6,RPL35,LMBR1L,MRPL33,RAD23B,PSMC3,CAPZA2,PSMB9,TP53,PSMB10,VTA1,SNRPG,CAPZA1,VPS16,PSMA5,CSE1L,MAP1B,PSME1,TCOF1,PSMG2,PSMD7,COPS5,GTF2E1,KARS1,MDM2,PSMB1,PTPN1,CD274,ZNF574,UBE2M,PRKCA,HEXIM1,GRM2,CFTR,PAAF1,PSMC4,SYVN1,DERL1,BAP1,SOD1,PRPF4,CDC73,PDCD4,UBE2H,FBXO7,USP14,PSMB2,VIRMA,ADRM1,PSMC5,RPS20,CCNF,PSMA6 |
| 7.206e-08 | -16.45 | SERPINH1 (serpin family H member 1) | protein interactions | 871 | 286 | 122 | 19454 | 5460 |
PDIA3,YWHAG,PPIB,YWHAH,AGR2,PEX3,POU5F1,CBL,FEZ1,PHB1,FOLR1,C1QL3,ATXN10,HNRNPL,NOP58,OS9,LANCL1,EGLN3,RAF1,TUBA1A,ISG15,FAF2,PDHA1,CHMP4C,EZH2,HNRNPA2B1,PDIA6,VDAC1,KRAS,PSMA2,AHCYL1,HNRNPDL,RAB11A,MYC,TOMM40,BTF3,BRCA1,ARHGAP19,BAX,NTRK3,DLST,LMBR1L,SEC61B,SMU1,LGALS3,ESR2,BET1,H1-5,EDEM3,ELK4,TOM1L2,CTBP1,PAK2,PPARG,CNDP2,PIH1D1,TMEM106B,PEBP1,AKAP1,HSPA8,ADRB2,YTHDF1,STAU1,STX7,PXMP2,COIL,FAM20C,CALR,DPP4,TIAM1,CD9,DNAJC7,AIFM1,COQ8A,SEC23A,MCL1,PREP,FZR1,TMED9,CAV1,CDK9,TMPO,TP53,MTCH2,UBL4A,UBE2B,TFRC,FURIN,C1QC,MAP1B,IGF1R,HSD17B10,ZC3H11A,SOS2,ARF4,SUGP1,CTSD,CEP70,CFL1,UBE2H,CTNNA1,CCNF,TXN,CTSB,SPR,ARHGAP1,SEC22B,UBA52,SLC35F6,CFTR,GABRA1,FGFR1,METTL14,RPA2,SIRT7,BAP1,RPA3,SOD1,RAB9A,HNRNPH2,FBXW7,HSPA5 |
| 7.309e-08 | -16.43 | EDC4 (enhancer of mRNA decapping 4) | protein interactions | 23644 | 210 | 95 | 19454 | 5460 |
PNRC1,MIR363,SFN,CUL3,MIR98,MIRLET7D,LMBR1L,PPARG,SUPT3H,NPTN,FXR2,MIR106A,G3BP2,RFC4,DDX5,DR1,AGR2,MIR1-1,MED4,DDX1,IFI16,XPO1,YWHAG,YWHAH,CPEB1,MIR29C,SUMO2,WIF1,MIR214,MIR141,PDHA1,CRKL,TOP3B,JUN,MIR222,WDR37,LGR4,G3BP1,DCP2,ARHGAP15,ABCF1,HNRNPA2B1,LSM14A,MRPS11,BAG2,TADA3,RC3H2,UBE2H,TADA1,TAF5L,VIRMA,CCNF,LURAP1,EIF2AK2,GSK3A,TRIM24,RPA2,EIF2B3,LSM2,WWP1,GIT2,MIR21,SUPT7L,HEXIM1,MIR1-2,CDC42,CFTR,SGF29,MIR107,HSPA5,RPA3,SIRT7,MIR205,LSM12,MIR34C,H2AC4,TAF9,MIR34A,MOV10,CCL5,EDC3,EIF2B2,CDK9,TMPO,MDM2,CDC5L,MIR106B,MIR20A,ILF2,TP53,MIR200C,LSM4,MIRLET7C,MRPS18C,MIR200A |
| 7.613e-08 | -16.39 | PTP4A2 (protein tyrosine phosphatase 4A2) | protein interactions | 8073 | 114 | 59 | 19454 | 5460 |
GPAA1,STX8,EWSR1,RABGGTB,BLOC1S2,FHL3,SNAP23,KRAS,TRIM26,VAMP8,AHCYL1,RIGI,PRDX4,SNAP29,SNAPIN,FNTB,CAPN2,STX12,STX5,ATP6V1A,VTI1B,SPTAN1,STX6,PTP4A3,HSP90AB1,DHX15,LAMP2,KXD1,LAMTOR2,AKAP8L,ATP6V1D,NAPG,GOSR1,MCMBP,STX7,GNB4,ATP6V1G1,ATP6V1C1,SPTBN1,SEC22B,GOSR2,PRDX3,STXBP1,DUSP22,PTP4A2,STX17,VAMP3,PSMC5,LAMTOR3,MYC,CARS1,STX16,CNNM4,LAMTOR1,BLOC1S5,NAPA,TNFAIP8,HSP90AA1,RIT1 |
| 7.613e-08 | -16.39 | HADH (hydroxyacyl-CoA dehydrogenase) | protein interactions | 3033 | 114 | 59 | 19454 | 5460 |
RPA3,COX17,CLK1,RTN4,GFM1,HSCB,LAP3,SPR,CDC42,NEK7,RPA2,ACAA2,IDH2,RNF103,PITPNA,MTRES1,CCDC90B,PRDX2,LDHA,STAT1,TXN,TXNDC12,CLIC4,AUH,MTG2,PMPCA,FBXO7,MTPN,TUFM,CGRRF1,PSMD14,FXN,UBE2H,HSPD1,HINT2,COX8A,PSMA2,PSMA1,ETFA,FKBP2,FASTKD5,ETFB,MRPL11,HADH,GLRX5,METTL15,PDHA1,RAD1,SSBP1,AIFM1,COX4I1,UBE2N,ANXA4,GATD3,RAB11B,MOV10,ADH1A,RHOG,MRPS26 |
| 7.613e-08 | -16.39 | PSAP (prosaposin) | protein interactions | 5660 | 114 | 59 | 19454 | 5460 |
UBL3,CFTR,GABARAPL2,PPP1CB,SSR1,KLF3,PRKCA,BAP1,SOD1,HSPA8,APPBP2,SRI,GPC1,BCL6,SAP18,HNRNPC,CUL3,MYC,CTSD,MCM3,ISCA2,BAG3,MTPN,BRCA1,FXN,NRP1,SMAD2,GTF2F1,ACTB,TSN,TXNDC12,TXN,CTSB,DYRK1A,RAF1,GLRX5,SURF4,HSPA13,MSRB3,BACE1,TCOF1,HINT1,UBE3A,SNAP23,THRAP3,CD1B,ZBED1,GUK1,LAMB2,RIGI,AK2,SMAD9,RPL9,GATD3,SNRPA1,SUMO2,OSBP,NUP35,HSP90AB1 |
| 7.737e-08 | -16.37 | TIPARP (TCDD inducible poly(ADP-ribose) polymerase) | protein interactions | 25976 | 1540 | 523 | 19454 | 5460 |
STT3A,COQ8A,SYNCRIP,NKAP,ILVBL,TMPO,CDC5L,KARS1,TUBG1,SNRNP70,CDK12,USP15,NOSIP,SLC25A11,RPL3,ABCE1,TMEM33,SRPRB,MNAT1,SRFBP1,NAA35,IPO8,CDK4,WBP11,ZMYM3,ZMYM4,CHAMP1,IK,TMEM165,ACADSB,PSMC3,UBN1,ZBTB33,PSMA6,LIG3,MOB4,QSER1,PSMC5,ABHD14B,EIF2S2,BUB3,ADRM1,PPP1R10,BCCIP,NAA50,GSTK1,CEP85,UTS2,EIF3G,SNX5,THUMPD1,RNF113A,KDM1A,EIF4E,ZC3H15,MARS1,HSPA5,SPTBN1,SUMO1,GTF3C4,SMYD3,RPA2,RPRD1B,IDH2,EIF2B3,E2F6,HECTD1,SRSF1,MAGED2,EIF2S1,AFTPH,FAM98A,TRIR,STK4,UTP6,FKBP4,CCT8,RPAP3,RUVBL2,RTCB,PDIA6,ZNF609,SATB1,RPL28,HNRNPDL,RANBP1,SOX2,KIF2A,UCK2,ZRANB2,MTA2,PHF12,EFHD2,PHKB,GTF2F1,GTF2F2,PHF21A,PSMD4,USP16,ATP6AP2,MLF2,FTSJ3,RBM27,NSA2,RFC4,HIRA,XRCC5,HSPA8,EP300,TRIM22,EMC1,EYA3,SSR3,STAU1,NUP62,TANK,NEK7,PLAA,CTBP1,PAK2,UBAC2,PIH1D1,AIFM1,HACD3,SRPRA,HSD17B11,EIF2B5,MAPRE2,TOP1,G6PD,EI24,GLO1,SLC2A1,PSMD7,DNAJC7,TOPBP1,SLC25A10,NSDHL,EHD4,RING1,SEPTIN7,ZC3H11A,HSD17B10,WASL,THRAP3,CTNND1,RPS13,RNF20,MDC1,EIF3E,MSH6,MTA3,YTHDF2,LBR,DDX39A,NECAP2,DMAP1,PPME1,SRP72,GSK3A,RTRAF,PRKRA,GANAB,DTYMK,TRIM24,ZNF622,TXN,RPL13A,SNX3,TECR,SEC63,CSK,PYCR2,AR,NONO,KPNA6,CHORDC1,XPOT,TADA1,PRPF4,FADS2,PNO1,CERS2,GTF2I,DGCR8,EIF5B,RPL4,SMC4,MBD3,TMEM209,CPSF4,PSMC4,EEF1E1,HACD2,TOX4,THOC2,IGBP1,XPO5,HP1BP3,RPLP1,COPS2,POLR3F,NOP58,OCRL,SPTAN1,SNX1,CCAR2,MPP1,ATXN10,SNX2,NTMT1,CACYBP,LRWD1,ZBED4,PSMD3,TAF7,STOML2,TRA2A,RHOG,PSMD10,RPL23,MORC2,TRIP4,PPAN,RPS24,UBE3A,RBBP7,G3BP1,GNL1,ETFA,MRPS17,MCM6,RFC3,RFC2,PCGF6,TPD52,FEN1,NUP153,GFPT1,STIM1,SF3B5,GTPBP1,CPSF1,PELO,RAN,RPL37A,AP2M1,RBBP4,RPL35,DYNLL1,RPL7L1,UMPS,MAD2L1,GNB1,TNPO3,RIOK2,SAMHD1,RFC5,RNF40,RHEB,MCM4,MCM3,BLVRA,MYO6,NUP50,NUBP2,TTC1,ATAD1,MCMBP,NSFL1C,COIL,POLA2,PSMC1,UNC45A,IDH3B,EHD1,ETF1,MED23,ADNP,MRPS9,RPL32,ADD1,CDK6,CAND1,RPS27L,EDC3,API5,SMCHD1,RPL24,KPNA1,AKAP8L,TAF9,MAP4,TRMT5,MYD88,MAP1B,CLPB,NEDD8,NUP107,PSMA5,CSE1L,HNRNPK,RPL17,RDH11,COMMD8,ESS2,DDX42,SURF4,CBX3,SLC25A24,SF3B6,PSPC1,UQCRC2,SEC61A1,PHAX,INTS12,EIF4H,CHMP5,AKT1,PSMB2,RAB2A,SMARCA5,SUGP1,CCNB1,RPL7A,PHKA1,MRPS16,CDKN2AIP,MAIP1,RPL27,DDX46,BAP1,PML,NBN,GTF2H4,CD2AP,TFIP11,TFB1M,SIN3A,CCDC71,PRCC,FUBP3,NOB1,RPS10,TTC9C,HNRNPL,OSBP,SNRPD3,PEG10,IFI16,BAZ1B,DDX50,RPL6,RAB5C,PTDSS1,SPATA2,DEGS1,DRG2,DDX1,ABCF1,CDK5,BCL9,NAB1,RUVBL1,RPS4X,CCAR1,UTP25,RAB18,TRMT1L,DHX38,PTRH2,TAF10,RPS23,MIDEAS,ATXN1L,CMTR1,ZMYM2,TAGLN2,MATR3,TAMM41,STAT1,LRIF1,POLR2B,RPL10,NCKAP1,ALG5,CREBBP,HNRNPAB,HNRNPC,PSMA4,PSMD1,CPSF2,RPS26,SERPINH1,SMARCD3,DDX39B,SF3B1,UFL1,TRA2B,LYPLA2,TOMM22,ZC3H14,MAP2K1,EIF4B,NUFIP2,CSNK1A1,CNDP2,RPL12,EIF4E2,MYBL2,RB1,RPL35A,COG1,NCBP2,CDK9,KIAA1143,CNN3,OSBPL8,NKRF,SFXN1,PQBP1,HUWE1,VRK1,FARSA,FASTKD5,VPS16,SMN1,PTGES3,TMEM126A,EIF2AK2,CTTN,TMOD3,COPE,FERMT2,SCML2,PDCD5,CEP97,TAF5L,ZNF687,RPL26,RACGAP1,AP2A1,CDC73,MAPRE1,RPA3,PPM1G,DVL2,HELLS,SPCS2,RTN4,BRIX1,SF3A1,SLC35E1,SYNRG,UBLCP1,STOM,RARS1,RPL9,MRTO4,TYMS,ATP6V1A,RPLP2,SRSF10,STK3,DHX15,HNRNPA1,RB1CC1,DICER1,PDAP1,ZYX,NUDT5,SCYL2,NEK9,HNRNPA2B1,SKA1,BAG2,SRSF7,ZNF592,PSMD12,GTF3C3,FOXP4,FLOT1,SSRP1,RAD21,ARFGAP1,RAF1,RBM12,HSDL2,NAA15,CSNK1E,ERLIN2,SKA3,RPN1,JPT2,SART3,SNRPE,SNRPD2,SNRPD1,IFT172,ZMAT2,TAB1,ACTB,USP5,PRRC2A,ERH,SMARCE1,MRPL16,JPT1,PRPF31,FYTTD1,BRCA1,SCFD1,RPS5,LSM14B,ARMT1,RMI1,TXNL1,PSMA3,ASRGL1,ACTL6A,MAPKAPK5,SKA2,ARCN1 |
| 7.907e-08 | -16.35 | USP19 (ubiquitin specific peptidase 19) | protein interactions | 10869 | 140 | 69 | 19454 | 5460 |
RPAP3,EWSR1,TRIM21,CAMK2G,G3BP1,TMEM33,VDAC1,CSE1L,SRPRB,TICAM1,FKBP8,RIGI,TBK1,MAP1LC3B,FAF2,CD2BP2,NFE2L1,ACADSB,PDHA1,BIRC5,AIP,TTC9C,CACYBP,HSP90AB1,LAMP2,CDC37L1,SEC61A2,ATG7,SIAH2,SMAD4,FKBP4,TRAF6,BECN1,MGMT,DNAJC7,IRF3,SYVN1,BIRC2,HSPA8,SQSTM1,DERL1,MAVS,DCTN3,ATAD1,CRYL1,UNC45A,G3BP2,OTULINL,FUNDC1,RFXANK,DET1,CFTR,CDK1,CCNF,STUB1,FKBPL,LMBR1L,SEC61A1,SIAH1,SUCLG2,MAT2B,TNPO3,APEX1,CUL3,HNRNPAB,HMOX2,MLF2,FERD3L,HSP90AA1 |
| 7.933e-08 | -16.35 | regulation of interleukin-10 production | biological process | GO:0032653 | 65 | 40 | 18204 | 5365 |
TLR2,HSPD1,FOXP3,CD274,MIR106A,IL4,LILRB1,MIR194-1,SYK,TLR9,HMGB1,SASH3,CD83,IL20RB,AGER,PDCD1LG2,PYCARD,TLR4,CD40LG,LILRB4,CD46,MIR98,ISG15,MIRLET7C,FCGR2B,IRF4,IDO1,XCL1,IL12B,RAD21,TYROBP,CD47,VSIR,IL13,IL23A,TUSC2,IL6,CLEC7A,CD28,MIR145 |
| 7.960e-08 | -16.35 | CHCHD1 (coiled-coil-helix-coiled-coil-helix domain containing 1) | protein interactions | 118487 | 241 | 106 | 19454 | 5460 |
RCL1,FTSJ3,MRPS25,HNRNPC,PMPCA,PYCR1,CBX5,NDUFAF4,MRPL23,RPL7L1,MRPL13,TACO1,DLST,NDUFA5,MRPL12,NDUFAF3,COIL,MRPS7,TRA2B,NDUFS2,DDX39B,MRPS26,MAGOH,PPM1K,WDR12,MRPL18,MRPL9,NDUFV2,CLPX,MRPS35,STOML2,NDUFS8,SRSF10,HNRNPL,NOP58,SRSF1,PHB1,NDUFA12,NDUFS6,H1-3,RAF1,SRSF4,MRPS17,HNRNPDL,SSRP1,KGD4,SRSF7,PREPL,MRPS16,CHCHD4,NDUFAF2,RPF2,PYCR2,IDE,MRPS28,MACROH2A1,MRPL53,EIF2AK2,UTP15,HEXIM1,MRPS34,ZCCHC17,POLDIP2,MRPL20,BRIX1,AATF,WDR3,MRPL17,MRPL40,MRPL41,TWNK,DLAT,ESYT1,MPHOSPH10,CHCHD1,GRSF1,MOV10,DKC1,MRPL24,MRPS23,SURF6,NKAP,MRPL50,BRMS1L,LDLR,PWP2,MRPS9,MRPL49,NEFL,RBM34,NDUFS3,PPIF,ESS2,BCS1L,IMP3,MRPL47,NDUFA2,IPO8,MEPCE,MRPS33,CDC40,IMP4,NOC4L,HAPSTR1,MRPS18B,NKRF |
| 8.259e-08 | -16.31 | AHCY (adenosylhomocysteinase) | protein interactions | 191 | 278 | 119 | 19454 | 5460 |
LDHB,TBCE,CUL3,MYC,MYO6,H2AZ2,BRCA1,BLVRA,SNRPD2,ENO2,PAPSS2,MAT2B,ACTB,LGALS3,PIH1D1,ARCN1,EIF4B,MAP2K1,DDX5,EP300,HDAC5,APPBP2,HSPA8,TMEM106B,FOS,NSFL1C,SERPINB6,GPC1,STAU1,HSCB,UFL1,DDRGK1,CTNNB1,XPO1,PRDX1,HSPB1,AGR2,ATP6V1A,DHX15,TCP1,ERLIN2,PPP2R1A,ACTN4,SOX2,TRAF2,HEXA,E2F4,RAF1,MOB3C,NME1,EZH2,EWSR1,CCT8,AHCYL1,HNRNPDL,PSMD12,RUVBL1,KRAS,GMPS,ATP5F1A,CARS1,UBE2H,SPOP,MSN,CTNNA1,SMAP2,CCNF,DYRK1A,UBA3,IDE,ADRM1,CTSB,NDN,GABARAPL2,CFTR,UBA52,ATG16L1,UBE2M,HEXIM1,JUP,RPA2,LMNA,DERL1,PML,BAP1,RPA3,INPPL1,MARS1,EIF4E,SMC4,NUCKS1,FBXW7,GTF2I,GAPDH,COPS5,HDAC6,SMCHD1,NME2,PTPN1,PRNP,CAND1,UBR7,MAP1LC3B,CCT5,TP53,RRM1,KBTBD4,FBP1,PSMC3,TFCP2,HSPA13,EMC2,ERO1A,GLUL,PSME1,PPP1R12A,HNRNPK,HUWE1,NEDD8 |
| 8.297e-08 | -16.30 | CYC1 (cytochrome c1) | protein interactions | 1537 | 216 | 97 | 19454 | 5460 |
RHOG,HSPB1,DDRGK1,NDUFV2,RAB1B,EGLN3,UQCRH,NDUFS8,PHB1,ATP6V1A,CORO1C,PDHA1,RPN1,NDUFA12,EEF2,ACTN4,PPP2R1A,VDAC1,KRAS,EMC8,IMMP2L,COX7B,NDUFA4,COX8A,MYC,TOMM40,ACTB,FBXO22,ATP5F1B,PARL,ESR2,LMBR1L,BAD,VDAC2,ARMCX3,ATP5PO,SLC25A3,MYL6,TOMM22,NDUFAF3,PHB2,EMC1,NDUFS2,UFL1,HSCB,HADHA,POR,ATP5MG,COX5A,EMC4,MTMR12,CALR,MOV10,GRSF1,TPM3,ATP1B1,SLC25A12,MYL12A,ILVBL,LMAN1,ATP5PD,COX4I1,AIFM1,SSBP1,NDUFS3,MTCH2,FBP1,APOO,SFXN1,RAB1A,EMC2,ATP1B3,UBE2H,ATP1A1,RALB,NDUFB10,TUFM,HMOX2,ATP5F1A,MGST3,VIRMA,UQCRQ,UQCRC2,CCNF,METTL14,HSP90B1,SSR1,SAMM50,COX6C,RPA2,CYC1,ATG16L1,CDK7,UQCRC1,PDHB,RPA3,DLAT |
| 8.312e-08 | -16.30 | SSR1 (signal sequence receptor subunit 1) | protein interactions | 6745 | 439 | 174 | 19454 | 5460 |
HMOX2,TMEM106C,CCNF,METAP2,VKORC1L1,TECR,UBB,SEC63,VIRMA,PSMC4,RABL3,COQ8B,SEC22B,TPT1,ARHGAP1,ST7,LMNA,SLC12A2,METTL14,TMX4,GRM2,PDCL,MET,RPA3,RTN4,SPCS2,MTDH,CERS2,YKT6,RPL4,TMEM209,TMEM199,NFKB1,EI24,ATP5MG,HM13,POR,ESYT1,OSBPL8,HACD3,SRPRA,PTPN1,HSD17B11,CCDC47,CCT5,EEF1A1,LBR,HSPA13,SRP72,SERPINA1,FAM169A,NSDHL,SFXN1,RPL23A,HUWE1,PSEN1,RIGI,MDC1,VEZT,CUL3,LMNB1,SCFD1,VMP1,ILK,ARF1,SEC61B,RPL35,RPL19,TOR1AIP2,PGRMC1,RND2,OTULINL,MED23,VAPB,NMRAL1,PTN,RHOG,CDK5RAP3,PHB1,CYB5A,ODC1,EGLN3,SLMAP,RAB11B,B3GNT2,MACO1,FAF2,RPN1,STIM1,EZH2,CYB5B,TMT1A,BCKDK,EMC8,RETREG1,KCNQ5,RPL7A,GORASP2,CHCHD4,UBE2H,UQCRC2,ATL1,SRP54,CDC42,GABRA1,CFTR,RPA2,USE1,CYC1,LEMD3,TEX264,DERL1,HSPA5,ABCC2,DPP4,EDEM1,DHRS7,SMIM12,AGPAT1,CD274,CAMLG,RNF128,RAC2,CAND1,ARL6IP5,DNAJC1,TMPO,DKC1,LMAN1,PREB,SNAP29,CDK4,UBIAD1,SURF4,RNF8,STX18,BCAP29,YIF1A,SRPRB,FKBP8,OST4,MYC,TMEM38B,CCT2,LMBR1L,ATP6AP2,ESR2,ATP6V1C1,BET1,SEC62,EDEM3,FDFT1,TMEM106B,RAB5A,UFL1,PHB2,SSR3,PTDSS1,RAB5C,DDRGK1,DRG1,NDUFB8,SSR2,SRSF1,STX5,RHOH,TCP1,ELK1,STBD1,TUBA1A,DNAJC25,RINT1,KRAS,NUP42 |
| 8.327e-08 | -16.30 | NIK-->noncanonical NF-kB signaling | REACTOME pathways | R-HSA-5676590 | 60 | 39 | 10285 | 3229 |
PSMA4,PSMC5,PSMB11,PSMB10,PSMA5,PSMB6,PSMA2,FBXW11,PSMD1,PSMB2,PSMB3,PSMA6,PSMD3,MAP3K14,PSMB7,PSMB1,PSMB5,PSMA3,PSMD12,PSMC1,PSMC4,PSMC3,PSMD14,PSMA1,UBA52,RPS27A,UBB,PSMD4,UBE2M,PSMD10,PSME2,UBA3,PSMD6,SKP1,PSMB4,PSME1,PSMB9,SEM1,PSMD7 |
| 8.349e-08 | -16.30 | breast | COSMIC cancer mutations | breast | 16375 | 4753 | 16828 | 4835 |
CCDC167,DBNDD1,GIPC3,NGRN,RAD1,NFE2L2,POLR2C,GNAQ,LPAR6,PITPNB,USP46,SMAD2,SNX3,TBC1D5,DBH,CLRN1,SIKE1,NDN,ARMC6,CHCHD1,PPIC,MMAA,NCOA5,RUVBL2,GOSR1,IGF2BP1,CRMP1,TCP1,KCNH8,HPS6,OR2F1,CH25H,TMEM19,SLC35A5,LGI1,CDC5L,TAF11,EMX1,PKIB,UBTD2,HNRNPL,IREB2,CD80,RABIF,ADRM1,CNOT7,TAF2,SGMS2,NCSTN,ANXA7,SSR3,LIN7C,PFDN1,SLC38A2,HS3ST5,PLAC9,GPR22,P2RY10,NKX6-2,DPPA2,PMP2,PI3,EIF5A2,SMURF1,STX16,FKBP4,PSKH1,CCL1,NGDN,CTRB2,PRR19,UBE2N,ANO3,PSMB2,FGF22,CX3CL1,TNNI1,PEBP1,ADRA1A,IL5,PTGDS,CTTNBP2NL,VDR,MYO1B,QSER1,SLC2A1,SRSF12,GPT,GPN2,SLC6A1,TLR4,ADRB2,VAMP1,CBX7,COL3A1,PAK1IP1,MRPL36,AMACR,NR0B1,FITM2,TRIM22,CYB5R4,SPOP,DEFB129,CASP4,SLC15A2,SLC52A3,B2M,TIFA,SASH3,TPRA1,SDS,DIRAS1,GINS4,ABCE1,PRRT1,CYP7A1,DCUN1D1,RPS24,MCM6,NUDT4,ITM2A,EAF2,DCK,ADH1A,LRRC8C,DMAP1,NOP16,ZNF32,KCNB1,TNFRSF9,OR7D4,PEX26,BAZ1B,OR4E2,PAQR8,PPP1CC,MYH1,IFT57,VDAC2,DCTN6,ACVR1,BCL2L1,YWHAG,ICA1,SCAMP5,CST3,PLEKHO2,LYZL4,LRRTM1,RNF152,UQCRC2,MRPL33,KLHL28,EDEM3,TPPP2,EGLN2,ATP2B4,SIGMAR1,IFNK,DUSP9,CFDP1,RBPJ,MRPL17,CXCL9,FBXL3,QRSL1,VIPR1,RPS15,ASB1,ACTN4,GATAD1,PTGES3,RGS10,RETN,NKRF,MCPH1,EDDM3B,ZDHHC8,ISOC1,LRAT,TCOF1,PSMB11,HSP90B1,TMEM97,NSDHL,MED13L,IDH3A,PATE4,RFC5,JRKL,MPST,PSMC4,ASRGL1,MFSD6,POU3F4,MADCAM1,ESAM,PCCB,HSD17B3,NEO1,RLN3,ANKRD50,SLC35C1,NXT1,YES1,RNF208,GRIA1,CRYGA,CBLN3,CLIP3,SLC25A42,VAC14,GAPDH,GKAP1,UBL4A,SERPINB11,RPL17,HDAC5,FABP12,FGL2,PI15,HECTD3,ACHE,UBE2B,CSE1L,IRF2BP1,FBXO3,STX1A,GUK1,AGAP2,CAPZA1,CLDN6,NEK9,FMO3,TNFSF10,CDK5RAP3,OR4N2,MNAT1,STAC3,FAM3A,SNAP23,FAM76B,RNF146,SAP30L,PDIA2,PICK1,NTRK3,TSSK1B,CCAR1,ELOF1,PAQR4,GGCX,BOLA1,TSPAN7,PIK3R1,ACOX1,F7,FADS2,IFT52,G3BP2,OR10G3,OR2J3,DCLRE1C,SUMO1,KDM2A,POLD2,KLHDC8A,EXOSC8,ZNF574,LMBRD1,UCK2,ITGA2,SLC31A1,DIO3,COX6B1,SRSF1,CDK2AP2,IGSF21,PRPF18,CAV3,EPHA2,FGF7,MAPRE2,MRPL41,RALYL,MRAS,CYP1B1,MDH1,ELK1,FAM168B,RAB28,COX17,DDI1,MMP14,RAB6B,ATP6V1G2,MRPS35,CBL,LHB,INSIG2,DEFB124,COPS4,KCNK17,ZGLP1,ANGPT1,NCALD,WDR6,ACOT6,IL12B,HSDL1,KLHL23,TMEM184C,NOB1,MED17,DCP2,BAG2,PHF12,ZBTB33,GEMIN7,PLXNC1,UGT2A3,TAAR6,BLOC1S3,PHC1,EPYC,SELENOT,GRAP,RIMS3,CUTA,DLAT,RMI1,CAMK2N2,PNMA2,ANKRD49,CD38,MT1A,PACRG,TAS2R16,OSGEPL1,HP1BP3,MCM8,UTP15,GRM8,EIF4E2,IL13,OR4N5,ZMYM2,CFL2,SLMAP,SNX5,EXOSC4,BUB3,JUP,DDT,ALKBH3,EXT1,MSRB3,EIF3E,CTBP1,CDC42EP4,FASLG,KLRD1,TIMM8B,IRAK1BP1,TMEM74,MGAT4B,PLP1,DCAKD,XPNPEP1,RNF41,ZNF7,LMNA,PHF1,DCUN1D3,CYP3A5,CD52,GTPBP2,C1GALT1C1,LGI3,EIF2AK2,TRIM27,COPS2,LIMD2,SRGN,KLHL32,RAB31,STC1,OR8K1,DYRK1A,DRP2,EIF2D,AIG1,NEUROD6,INSM2,NCR3LG1,TSHR,SLC25A20,RALGAPA2,PPTC7,PCK2,GANC,ACO1,SATB1,TRA2A,PRMT5,BEND6,G0S2,OR5I1,TAS2R46,NOSIP,NR4A2,UBXN6,KCNF1,NME2,CD4,SFXN1,UBAC2,MYT1L,USP2,CYB5R1,LRTM2,POC1B,GPHA2,REXO2,DTD1,NELL2,NDUFB5,TM2D2,SUB1,OR52W1,SCN1B,CDC40,CPE,SLC39A13,CYP4F12,DCAF4,PCSK2,ARHGEF6,ERP29,PTTG1,BCCIP,TM4SF1,IRF2,MCAT,SEC63,NUDCD3,INPP5K,NOVA1,DEFB115,SSBP3,NXPH3,TACO1,NSA2,WFDC5,CAMK1,NOL7,SNX2,TRIM8,FAHD1,RPL13A,TAGLN2,RPP14,HRAS,WDR20,SYT4,KIF3B,HTRA1,MITF,LCA5L,IKBKB,HELLS,CRB3,DHRS7,VLDLR,VAMP3,WDR83,CLVS2,IQCF5,PHF23,COX10,BSCL2,RNASEK,CDK8,MTX2,MAEL,TFG,CYB5A,ELOVL3,ALKBH2,SKA3,RPS29,DEFB121,NCKIPSD,CTSB,LRTOMT,NFE2,SLC16A4,POGK,TRIM52,HNRNPA1,ACOT8,LECT2,PPIA,FBP2,RSPH1,ZDHHC15,MAP3K12,COX19,SOX3,RPS4X,TMOD3,ZSCAN5A,VSTM2A,B4GALT7,SMCHD1,MRPL40,CD1E,GTF2IRD1,TRMT11,CLCA1,CNOT6L,PGM1,NAT9,HADH,RPL8,IKZF2,CLEC9A,MRFAP1,MEF2B,WASF3,PRKCQ,GABRG2,TFIP11,MAD2L1,CA10,MAP2K6,RASGEF1C,PCMTD1,TOMM7,SEPHS1,ANAPC11,LACRT,VPS4B,TMEM160,FOXP3,LDLR,OR7E24,RBM42,PPP5C,GSTA4,RHBDD3,TREML1,SOCS4,MED9,GHR,MED30,CXCL11,SLC6A8,CUL2,PYCARD,GNB1,GLTP,CDC16,ASB8,ORMDL1,INPP5E,SF3A1,GNAI3,PSPC1,TRAPPC10,MCHR1,SFN,ZNF596,RING1,RBFOX3,SSR1,AVPI1,SMARCD3,NETO2,CHID1,DISC1,COIL,ZFP64,TUBB,LSM14B,STX10,FAM50B,SFTPA1,SYCE3,TIAM1,THAP2,IL4,PAQR9,TRIM63,FAM110B,STBD1,OVGP1,EMP2,LILRB1,GLRB,EHHADH,TRIM46,GPX2,HCLS1,DNAJC1,IL15,MRPL10,YBEY,NTPCR,PNOC,CYP27B1,HMG20A,BTF3L4,ARL6IP6,TLE1,UTS2,RRN3,DHPS,NIF3L1,TMEM14B,GNG5,NDUFB10,POMT2,POLR2F,PADI2,OGN,SCPEP1,TMEM190,NSFL1C,NUP50,IFNGR1,TPGS2,NDUFA2,RIMS4,OSGEP,SCN3B,NMI,LRRC57,PLSCR4,MOG,SPATA6,FAM162B,GLT8D2,VTI1B,ARHGAP5,CCL20,MRPS7,ZNF575,LIN7B,PCDH9,ZRANB2,ARHGAP25,DES,RIC3,TCAP,MYOZ3,EIF4E3,FTL,TMC7,LRIF1,STIM1,GRPEL2,FLRT3,TNFSF13,CD248,ZNF668,RSRC1,RPL35A,MSL2,FLCN,CXCL12,SLC25A28,SLC39A3,SERPINI1,IDO1,PPM1D,KLHL12,SH3BP5L,MED31,NAA50,FCGR2A,CELF6,TUBA1A,RPL7,YTHDF1,CHST11,HMX2,UNC50,ICAM3,LUM,SEMA6C,CCDC85B,NEUROG2,MTMR6,HNRNPD,PDCD1,MS4A7,KCTD15,PAFAH1B1,SLC25A11,CKLF,CCT7,PSMD12,RGS19,RCE1,MGAT1,RASGRP3,ENTPD3,CDC42EP3,RNF115,MCM3,RAB33B,SECISBP2L,IFIT2,PIP5K1A,IZUMO1,PEG10,PSMB6,ZCCHC17,BAHD1,DHRS7B,PTGER4,TOMM20,TRAF3IP2,NLRP6,CHRDL1,CD2AP,SRC,VPS28,MPZ,KRTAP12-4,IFNA2,IDH1,TUFM,GNG13,OR51M1,RASL10A,SULT1A3,METTL6,TERT,SLC35B4,MKKS,PIK3R3,LANCL1,CISD1,MORC4,CHCHD3,NFKBIB,ZNF280B,MMP21,EID1,EPO,CCSAP,RPS13,UGDH,PGAM1,AP2S1,RNF121,PTPN22,SOCS3,FOLR2,PDRG1,DCUN1D5,PPIH,HDDC2,CD1A,LPAR1,HSP90AA1,RFC2,SNX18,TYW3,LNX2,MATN4,DDAH2,ACTB,ZER1,CNTN1,GNB4,CPNE1,NPY,SLAIN2,CAMLG,PLA2G12A,CNR1,TAS1R2,ZBTB2,MFN1,DAD1,GGT7,GRXCR1,PSMA2,DNAJB2,EFHD2,PPP4C,PPIG,NRBF2,UBFD1,NAA35,GSTM2,COMMD5,SST,PFDN4,GABRA2,RAB30,RSAD2,NICN1,TMEM208,RERE,GRID1,PPP1R12A,CCDC122,IL6,SYVN1,HSCB,CES5A,TFEB,GABRB2,ARMC1,LGR4,HECTD1,DYNC1I1,FGF10,TLR2,DNTT,OSBP,GOLGA5,RLN2,OR9K2,NDUFS3,HPGDS,SSRP1,PAIP1,TTC32,OCIAD2,TWSG1,MED21,PSMC1,TBC1D4,UNC119B,RPAIN,XXYLT1,GIMAP4,MORN4,ISCU,FCHSD2,ELAVL2,MOSPD1,OR5AP2,UBE2M,PIR,TRIM10,SLC6A12,UBE2E3,AGAP1,KBTBD4,PNO1,CYP2F1,PSME1,CLVS1,FAU,RAB22A,AK5,GTF2E1,TNNC2,OR8I2,SMC4,FZR1,SLC22A8,DRD1,SMAD4,SLC1A3,GPR85,PPP2R3A,BAK1,ATP1B1,ELK4,FAIM,SMARCA5,CNPY4,DRAM1,VKORC1L1,IL1RAP,FXR2,AURKAIP1,AKR7A2,FOXP4,TMEM182,RNF126,LDHB,RPF1,GPBAR1,ITGAV,USP5,MXI1,FERD3L,NUP37,LRRC1,TM9SF4,TCEANC2,ELAVL4,RPS27L,SEC61A2,STK11,COMT,TESK2,GOLPH3L,TNNT2,TP53INP2,GPSM3,LAMTOR3,ZNF175,SNRPD3,SEC62,FGF12,RIMKLA,GPX4,EXOC1,PHAX,BAALC,FKBP10,TMEM106A,ANGPTL2,LY6G6C,RHCE,FUT1,DOHH,BAP1,PLAA,RPRM,GPR26,IL1B,SYS1,ARL4A,ARFGAP3,LITAF,LRRC4,DRAP1,MEF2C,RGMA,DNAJC10,IRF6,RAF1,GPNMB,PRRG1,SAT2,RNF14,GTF3C3,CSTB,MCHR2,KLHL7,OR51A4,DET1,ZNF330,SCYL2,COG1,RPL10L,PHKA1,ALG2,MBLAC2,UBN1,TPSG1,UBE2F,FOXP2,CYP17A1,SLC22A12,SNAPC2,CCHCR1,RPS5,PDE9A,SLC1A1,CCDC71,CYTH1,DDX5,EIF4A3,ADNP,LAMTOR1,RAP2C,GSTK1,NAE1,RPS11,KCNMB2,GTPBP1,TMOD1,TNFRSF14,TXNRD1,KATNAL1,AZI2,ARL15,ILVBL,EGFL8,NDUFA12,NUDT5,TGIF2LX,ATP1A1,CRKL,B4GALT1,STARD13,AOX1,PSMA5,DNAJB6,ZFAND2B,KDSR,CD1B,LRRN1,GCC1,DNAJC27,RP2,CENPP,STX12,FBP1,GZMK,CNPPD1,NLRP1,NRSN1,HOXB1,RHOB,OR4K17,TMUB2,MAX,YIPF4,CSNK2B,LCMT1,MRPS18A,TRIM11,C1QL3,VMO1,PROM1,TOPBP1,QPCTL,RBM18,RPL3,MTG1,GLRA1,G2E3,E2F4,MYD88,FCF1,MRPL52,CD1D,PLN,GLYAT,GFI1,TMEM209,FLRT2,BOLA3,DEDD,PPM1G,CDC42EP2,CBX5,ARL10,MYCT1,FAM118B,MAGOHB,TM9SF1,COMMD2,SVOP,PEX5L,CDC123,UCK1,GNAI2,GABARAPL1,CD46,KCNMB1,TRMT1L,MICB,NUP153,TOR1AIP2,STOML2,OTUD6A,GPR15,PPARA,COPS7A,RNF20,ACTL9,GTF2A2,TPT1,SNCB,ATL1,RRAS2,POLR3F,RPL35,FRS3,RERG,ASB3,CHMP5,ZMYM4,EIF2S2,BTG1,AGPAT1,GNA14,CXCR6,CISH,TXNL4A,TSC22D3,NANP,USP14,DUSP26,EYA3,CNTNAP1,ANAPC13,TMEM176A,HDAC6,PBLD,RNF39,PSMD14,THY1,TESC,YWHAB,ZNF692,SLC25A44,CDSN,SESN3,PHB2,TTC1,MMADHC,NR1H2,BMP1,PRPF31,TMEM95,LEPROTL1,SYT2,SPOPL,TBC1D24,ST6GALNAC3,EDNRA,TPBG,KCNQ5,DAPK1,PDE1A,LILRA1,STXBP6,ZCCHC12,ARRDC3,EEF1G,LRWD1,SLC25A17,NFYB,ODC1,SLC25A23,DSN1,ZC3H15,SFTPC,SLC6A4,PDSS2,YIPF5,TOB2,FNTB,NME4,CDK5,GNG3,MRPL51,PATE2,RNF26,RAB13,OR10G2,MAP1LC3A,SNAPC5,RPP21,NDC80,PLAC8,CYB5R3,DRG2,THBS3,SNAI2,TRUB1,CALR,MAMDC2,TSG101,ADCY2,PKIG,MOBP,OAF,HEXB,SYNGR4,PPFIBP1,CYTL1,NDUFA4,SLC45A3,SHMT1,MSX1,CHRM1,IL3,DLG1,P2RY11,TLR6,RPN1,CD151,KCTD9,STAT1,ZNF507,PAX6,MRPS33,LMBRD2,LMO3,UGP2,EIF2S1,HEXIM1,DPP4,PRDX2,PC,RAB5A,APOBEC3D,NEK2,NDUFV2,ZNF526,NDUFB7,KCNA3,F10,SSBP1,PTN,TMEM31,SP4,OR4N4,ZBED4,DYNLT3,CD79B,WASL,SDC4,GOLGA7,REP15,TMCC1,RAB14,BVES,EIF3G,MEPCE,CCIN,UBE2L3,TTPAL,PMAIP1,PDE4B,SPEM1,CYP3A43,CSNK1G3,RAB39B,MRPS11,AKR1C1,SREK1IP1,FTSJ1,CNTROB,ABHD10,HUWE1,CPLX2,PRND,NDUFC2,TMEM205,TRIM34,RGL2,ITGB5,BLCAP,ICOS,NINJ1,CAV1,B4GALT4,RPS2,YIPF3,LXN,TCEAL8,GSTA2,TMEM127,HCAR1,MCL1,FAM53C,ALG11,NDUFA1,DDAH1,GPR35,HFE,ZBED1,DPH5,PNMA3,RB1,TRIM29,OIP5,CORO6,TNKS2,LILRA2,LY6H,HSPB2,COMMD9,CBLN1,STK3,DCAF12L2,PLSCR1,PTP4A3,CREBZF,PAQR3,JAK2,PROK1,MRPS18C,NT5DC1,TRIM36,ING2,ARL2BP,CHRM3,TSR2,SPP1,FAM149B1,FRZB,PRSS23,GPR17,GPC1,PLCB1,ZNHIT6,GXYLT2,KCNJ2,EPHA4,NPY1R,PSMD10,GCLC,CPLX3,TNNI3K,LIAS,ARL4D,CITED1,CDK12,DLK2,PLG,DMTF1,TNFAIP6,FBXW7,PSMB7,MAGEB10,CXCR3,HOMER3,TAF1D,SHPRH,KCNJ10,ADORA1,SPATA2,SLCO3A1,OR4K2,GRM1,PCGF6,FAM81A,EHD4,ZNF511,CEND1,STAMBP,HNRNPF,SLC25A1,OST4,STARD3NL,YWHAZ,ICAM2,ABHD8,OR8H3,SLC8A1,LSM14A,CAPN2,BOK,OR6X1,TNR,TM4SF18,SLC29A1,SURF2,GJA1,MAGED2,CCNA2,TM4SF20,RNF222,REEP4,AASDHPPT,MIS12,TMEM89,CAND1,PRNP,HSD17B10,GABRA1,ASPA,BCL9,LYPD6,ELMO2,TRPC1,HS2ST1,GTPBP8,DR1,CBX3,GTF2F1,DLST,GSTCD,E4F1,TMED9,SYNPR,BCL6,SSX2IP,ZNF263,TPPP3,SGTA,MTDH,USP6NL,CA2,SNX10,APEX2,ADORA3,SF3B1,TAB1,AKR1B1,MAD2L1BP,TMEM47,LY96,AP1S2,ANKMY2,CNN3,CPT1B,ZBTB39,RBM27,CDH11,PSMC3,JAKMIP2,SNRNP40,FAM83B,IVNS1ABP,PIK3CA,PAIP2,NDUFS2,TMEM185A,PSD2,BAX,PEBP4,GH1,ATP1A3,NUDT2,NPM3,TSPAN15,TMEM38B,GSTM4,CRTC2,RPIA,VTA1,COX6C,PICALM,LST1,XAF1,PIK3AP1,FEM1C,COCH,TAS2R13,DBR1,ZNF451,PRKCE,GNRH1,WDSUB1,PRKRA,TSPAN17,COX6B2,RNF133,TMEM170A,MT1E,DPH3,LRRC40,CRISP1,ELK3,CD81,SLX1A,RHOBTB3,HGS,POLDIP3,POLR2L,FSTL1,UBE2E2,NUDT9,CYGB,IL17F,PPAT,TNF,GGH,CCR4,CHRAC1,KLF3,LZTFL1,SNRPB2,SUMO2,TFB1M,CGGBP1,PHF13,RPL26L1,PARP2,NF2,ABHD12,BANF1,CARTPT,SESTD1,KLHL1,FOXA3,SGMS1,RBBP8,MGAT4A,ATAD1,TRIM45,DUSP21,IGSF11,CYP2C9,MRPS34,CDC7,MPPED2,PRL,FBXO8,NDST3,SLC19A3,OLR1,TYROBP,WDR11,NHEJ1,SLC35B3,FHOD3,AIPL1,PEX13,TBC1D25,TNFAIP8L1,NBN,VMAC,IL2,SEC13,WDR5B,ZDHHC4,CDC20,SNRPG,ADTRP,ACCS,TIMP4,XRCC5,CPNE2,IFT172,CYTH4,TMBIM1,RAMP3,KLRC2,TOX4,CENPL,TRIM26,NUCKS1,IER3,FEM1B,MRPL9,UBE2G2,MECR,SGIP1,MRPS17,FXN,UPRT,SUPT3H,WSB1,LYZ,TOPORS,OAZ1,SLC25A5,PRR13,FAM136A,SLC35E4,FAM151B,CYBRD1,MACROD1,ZNF518B,ADCK1,RPE,SULT1B1,KLHL25,TMEM165,OR8B4,IRF7,PTP4A2,FAM3C,MFAP3L,SLU7,VEZT,KCTD3,PIH1D1,RDH11,LBX1,NKAP,LRRC8A,SSPN,CNPY1,GNGT2,HAUS2,OR5M9,GALC,RP9,ELFN2,DMPK,ELFN1,MBD3,CDC23,MPG,TANK,SYNGR3,BRAP,TTC9C,GMPS,PELO,THUMPD1,GORASP2,RXRG,SNAP25,CCR7,IGF1,CMA1,DLGAP4,GRIK1,RRAGB,SNRPE,GALNT2,IL18BP,RASL12,ANXA4,RUNX1,SLC12A2,RPS20,GJC1,NAA16,TAPT1,MED10,TYMS,ZFAND6,SCML1,DUSP3,SUCLG2,PDE7A,ZNF581,VPS18,GHRL,CIAO1,ATP8A1,KIF3C,PSEN1,MAGEC2,OR13A1,LCORL,EDA2R,FKBP1B,LMO2,RBP2,TLCD1,AQP11,SSBP4,RASSF8,KCTD17,CLEC6A,DIRAS2,MREG,ACER3,ARHGAP12,EIF5B,PFKFB2,SRFBP1,FAM161A,ANKRD6,PDE12,YTHDF2,IMPA2,FUNDC1,AP1M1,ECHDC1,UBA52,TMEM196,TRAM1,TADA3,MGMT,SP1,CCSER2,ITM2B,MTCH2,MDC1,TRAPPC6A,ROCK2,KCND3,FUBP3,VPS72,KRIT1,TBCCD1,TRAF6,RPL18,GIN1,TKTL1,CCDC106,ETNK2,CLDND1,RPS10,SPRY1,ZDHHC16,TEX261,OR4D5,MSH6,RAP2A,PPP1R11,MDFI,POLR1D,GPR160,DTWD2,PSMD3,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,POLE3,KRTAP8-1,GP9,OR51E2,RNF10,FAM133B,GLCE,SSNA1,GK5,SLC25A24,SUPT5H,PDCL,RPL10,TRIP4,STAR,ST3GAL2,TAS2R7,CD209,FBXW4,P2RY4,IP6K1,IL2RB,PTGFR,TAB2,SRPK2,RGP1,CCDC90B,PIWIL1,TRAF3IP3,TMEM107,RPA2,RNASE9,GADD45G,YPEL4,PRSS8,LDB2,TMEM100,DCTPP1,OR4A47,PRCP,EID2B,CPXM1,THAP1,UNC79,CD34,FBXL4,ZNF428,PDE2A,TNFSF8,CDIPT,PYCR2,FKBPL,RAB6A,RGN,CTTNBP2,PLAC1,SCAND1,PSMD7,SIN3A,CDK7,CRY1,CD40,AIP,SLC6A2,TNFSF15,PMPCA,TLR8,MED22,ARFGEF1,NOG,ZNF622,ATG9A,S100A11,VPS54,SLC25A27,RBMS2,TGFB2,BOLL,MX1,GLOD4,PIGA,THOC3,BTG3,DPEP3,TMEM183A,IGFBP3,GADD45A,GRPR,RUSC2,CD9,OR1M1,RNASEH2C,HSPD1,EIF1AX,LRRC28,TCEA2,PARD6A,NPC2,TMEM115,NUPR1,PNPLA4,PIAS1,CAP2,TMEM81,EXOC3,SAP18,DDR1,SPG21,TIA1,SLC22A6,FHL3,TICAM2,FAM20B,PQBP1,GPRASP2,PPWD1,NRM,THAP8,WDR45,CRYBA1,MPV17L2,HSPB6,GNA11,SERTAD2,HSPA5,ITGB8,BTG2,VAV2,CCDC3,GNB3,HINFP,NUFIP2,CMC1,TMEM229B,TRIM44,LRP10,NR1I3,RANBP1,CTLA4,RBM5,ATF3,MAP1LC3B,PRSS37,PDLIM3,IFRD1,DEFB1,ACSS2,RHOU,B3GALT4,DLG3,CEBPE,RPL22,TMEM176B,SNX11,RPLP1,SERPINB9,MT1X,UBE2V1,TIMMDC1,IMP4,TRNP1,HELT,PDE6A,CENPM,EMX2,SEC61G,SSH3,HOXB8,GFM1,ADIPOR1,PRM1,GAL3ST4,MET,FZD6,POPDC3,RETSAT,SLC7A11,SNN,SNRPA1,ANKRD46,CEP70,ABHD2,ARL6IP5,CTDSPL2,DTL,PSMG2,NDFIP1,KDM1A,CCDC22,TBCEL,UNC45A,FKBP2,PRSS35,ISG20,TMEM87A,RALB,NUDT1,GMNN,CYP26A1,CAMKV,F2,ARL5B,ESYT1,ANKH,VPS26B,YKT6,AANAT,EDC3,HAPLN2,SAP30BP,WNT2,GMDS,TRAPPC3,NRGN,CSRNP3,LDB1,MFSD3,BIRC5,RASSF4,KCTD20,SERPINA3,CLK1,SKAP2,RSL24D1,TRAF1,BRS3,ZMAT3,NAA30,C9orf72,CDR2,PTGER2,NETO1,DDX39B,CGRRF1,LSM4,HSD17B8,IRF9,SEMA3C,DOK6,PSMB4,HERC3,LRRN4CL,PDCD10,GDAP1L1,SSBP2,WTAP,RPL31,ZSWIM7,MGST3,TSPAN3,BAD,HAS3,OLA1,PRPS1,AKR1E2,CRHR1,NOC4L,UQCRC1,CDKN1B,CMBL,COX7B2,SCHIP1,HMGN4,MEA1,TAF9,SCG5,PHOSPHO2,NMRAL1,MAT2A,RFX5,TMEM198,TRAPPC2L,OR6C4,CD200,TMEM168,ST8SIA4,USE1,TMEM220,NCK1,STRADB,LRP3,SIAH1,PLEKHF1,AHSA1,ZBTB6,SLC15A1,KCTD16,GPR78,HNRNPAB,ZNF655,TEX19,TRIM62,KLF12,MLN,IAH1,WDR12,GLO1,RAB1A,PDCD1LG2,NEU1,VSTM4,AMELX,PIGK,PELI1,CNOT8,MAP1B,ZDHHC17,FBXO31,VSTM2L,SCN2B,ANKRD10,TEF,TCTA,PCP2,SOD2,ADD2,DCAF16,CLRN2,SRD5A3,OR4K13,DNM2,TSPYL4,C1QL2,PLCXD3,REG1A,MMP20,GTF3C4,SMARCB1,HTR2A,ACTR1B,STAP1,STARD5,FMO1,ABCC2,SUGP1,ALG5,DEXI,RIMKLB,AQP3,PRELID1,ETFA,CD59,ECD,PRSS1,APEX1,PSMC5,ITPRIPL2,JMJD8,GAB1,AKT2,CHST10,KCNG3,SOX9,OR2D3,PNPO,COTL1,GPM6A,HS3ST3A1,TICAM1,HIGD1C,TLR5,LCN1,RFC4,SEMA7A,NAP1L5,APOC2,CYB5B,ZCRB1,MED4,BCKDK,OR9I1,TRMT5,HPCAL1,LIPT2,MRGPRX1,TBC1D1,GPR34,XBP1,RPF2,TIMM13,GABBR1,ERCC3,THG1L,PDLIM4,TACR1,ARHGAP19,CEP57L1,OSBPL8,CA14,DIS3L,NAP1L3,CEACAM5,DRD3,MTA3,EMILIN3,CHRM5,NACC2,TMEM126A,SETD3,GPR75,ACP2,FOSL2,GNPAT,ACTL6A,STARD7,DIO2,EGR1,WBP11,ZNF436,ZNF343,SYPL1,CHTOP,CORO1C,RACGAP1,RBM3,RRP7A,CCDC126,STT3A,MAGEA4,PIK3CG,RPSA,NPBWR1,HYAL2,UBE2S,ERLIN2,ARHGAP15,RHOH,OPRL1,LYPLAL1,HSDL2,DYNLL1,PLP2,DUS4L,ABCF1,SMG5,NUP62,RNF139,ADRB3,FMOD,TBC1D16,CA12,SLC7A1,SPATA4,CMTM7,LEMD3,IRF4,CSRP1,CCND3,STX5,ARL6,RAB11B,MARCKSL1,IFNAR1,SDR16C5,SLA2,THOC6,TNPO2,HINT1,RPAP3,RXFP2,RAB9A,CCL11,MB21D2,LCN15,PGAP3,TCEA1,HM13,BCAS4,SLC39A10,MCCD1,VCPIP1,OAZ3,JUNB,ALCAM,SNRPD1,CCL24,LIPA,RNF182,RELL1,TIMM17A,SMAD9,UFSP1,PTPN5,CYP4F22,MVD,STK38L,PIGC,ARFGAP1,SHC3,CDC26,PREP,SLITRK1,DDIT3,SRP72,EDEM2,FIS1,RPL28,CACNB2,HCFC1R1,RBM41,COPE,RWDD1,SLC25A3,PABPC5,HCFC2,LSM5,DCTN3,PRKCB,IRF2BPL,RGL1,SUV39H1,RPL4,SEC14L5,SPAG11B,HBP1,CKS1B,DYNLRB2,DIRAS3,TP53TG5,ATG16L1,SIGLEC5,HDAC11,TTLL10,CHCHD2,SKP1,CSF2,PCYT1B,KRT8,PRELP,GJB1,GCHFR,HNRNPH3,LCP1,AGGF1,TPST1,ZNF200,IZUMO2,IFI16,PTPRZ1,SART3,MYLIP,SUPT4H1,FAM174A,VPS39,INA,CFTR,ATG3,CLP1,CLPX,OR5AN1,VWF,ATP6V1D,CDKN2D,ESD,GPR37,TMEM39A,ART5,PSMB10,CDK17,CRYZ,FOXC2,PITPNA,RAB32,CRYBA4,BLVRA,FAM193B,APOBEC3B,MLH3,PCBP4,TULP3,HS3ST1,BMPR1B,OR4M1,SPDYE4,ADH1B,RANBP10,MED27,SRM,PSMD1,BARX2,MPP1,SEC61A1,TTR,METTL18,RSBN1L,GAD2,BGLAP,CDC42SE1,COX7B,RHOG,NOL12,FAM83A,ASB11,RGS1,SDHC,KIAA1958,EID2,ZNF345,FOXD3,FBLN5,LYRM2,MAEA,CXCL10,SLC37A4,CDH7,ASCC1,SMUG1,UBXN2B,DUSP18,TPD52L1,ZNF770,ZHX1,SERTAD1,KCNIP2,ERRFI1,FA2H,HNMT,DPAGT1,CTSA,ZCCHC7,PHTF2,PPIL3,GPR83,LPCAT3,BTBD10,PDCD5,PRDX3,EMILIN1,LRRC14,ZBTB26,CKB,TUBA1B,THAP6,HMGB1,PHF7,MRPS26,GNG11,EIF2B2,ZMYM6,ARF1,DCTN4,MAP2K3,SEC22A,DOK5,FIG4,LSM12,CXXC1,RPL7A,SPHK2,FAM20C,RCHY1,MRPL12,FGR,B3GALT2,PPT1,ARF6,LRFN3,TNIK,S100B,PDE6D,OR5K1,PDZK1IP1,OR4B1,UBE3A,SH3BP4,LEP,SMARCE1,PITHD1,ZC4H2,CETN2,TADA1,ZC3H14,CBFB,ASPM,EFNA5,IFNA13,CACNG3,RIT2,MID1IP1,TDP1,SPCS1,GLIPR2,PLEKHF2,SNRNP70,SERINC1,SLC6A7,MAGEB1,DICER1,SLITRK5,SAP30,RNASE4,DDIT4L,FGF16,POU5F1,MSN,HBM,ZNF362,RPL19,IL21,ARL11,FHIT,MAP3K3,KRTAP4-1,TECR,MRPL16,RNF7,EZH1,ARGLU1,PNRC1,SLC41A1,LAMTOR2,MXD1,MFAP1,UBE2I,UCP2,TMEM106B,H19,SPRED1,NONO,POLL,TSSC4,MAK16,ALDH1L1,EIF4EBP2,OR2A2,HPCA,SV2B,ZNF805,SOST,TCP11L1,GPR37L1,NDUFAF2,SNTA1,SNAPC1,GFOD1,SIVA1,EMC4,ZBTB42,TNFAIP3,ABHD16B,RAP2B,MTMR12,DUOXA2,MMACHC,TRAF7,IQSEC1,NOL4,FYTTD1,SIRT7,ETV6,RRAGA,TAPBPL,CWF19L1,CDK6,DCAF5,ESR2,SNRPD2,FAM13B,ADCY3,CLEC12B,OAZ2,SFTPD,SOCS2,INTS12,CYP2D6,CTNNB1,RAB8B,PROX1,PRKX,FGF13,RTP4,ZMAT5,LSM6,SYNGR1,NAB1,ENPEP,VPS4A,USP39,CERK,SLPI,USP38,ZNF174,OTUD6B,SETD4,LCN6,FBXO9,COX7A1,WFDC13,ACOT13,TMED3,RPGRIP1L,OR2W1,CCND1,KLF10,MRPL47,S100PBP,TMEM33,MPHOSPH10,AP3S2,ARHGAP21,SCG2,RHCG,SPINK13,BMPR1A,FAF2,CETN3,URM1,CTSK,CACYBP,RAB3C,MTAP,PWP2,DUSP1,TGFB1I1,BATF,TOLLIP,STX8,S100A10,FAM200A,NFYA,CPT2,CHST9,ANP32B,NDNF,AP1G2,DCAF8L2,NLGN2,DEK,SLC5A6,CYP4F8,PRKD3,SPEF1,NUP107,OR52M1,SCAMP2,CD164,BPGM,CDKN3,PPIB,MRPS25,RBCK1,NFE2L1,AKR1A1,NOP58,SPATS2L,MRGPRX4,FABP5,CTSD,PGAP2,COA4,INPPL1,ING5,BACH1,MIA2,KIF2A,ENTPD4,SLC35A2,ARMC8,PTDSS1,ID1,POU1F1,CYC1,CCDC42,NPTN,FCAR,CRYBA2,DEGS1,XPO1,EXOC2,GJA10,SLC25A32,EFHC1,KIAA0040,EEF2,THRAP3,CREB3,RNF103,TF,INTS10,SURF4,XPO5,GPR162,APOBEC3C,ZNF513,SLC7A4,ZMYND11,SLC20A2,PCDHA5,UBXN10,PFDN6,LDHA,NUBP2,PRCC,GSK3A,ABCC5,THOC1,RANGRF,RC3H2,FATE1,ATP2C1,DNAL4,GNMT,CCL25,CREBL2,TXNIP,AQP4,GLE1,WDR37,EIF4EBP3,OR51S1,ZSCAN1,SLC39A9,FURIN,DHX9,PSMD6,IL23A,GALE,SH3GLB2,EIF2B5,CIRBP,ANKIB1,ENDOD1,OSR2,CXXC5,MOB3C,LASP1,PHKG1,SPOCK1,NEK7,UTS2R,GTF2A1,WBP2,FUT8,PGBD2,SIPA1L1,STAMBPL1,CLDN14,ZKSCAN1,HSPE1,RPL37A,SERPINH1,RAB4A,SOX21,TRA2B,DHX16,LEAP2,HADHA,LHFPL1,B4GALT6,HSPB1,KCNA2,GXYLT1,OR6M1,NUDT16,FRA10AC1,PDIA3,XPOT,CXCL1,ISYNA1,NDUFB8,APH1A,EIF1AD,NAA11,LEPR,STX17,WNT7A,MSX2,NLE1,KRR1,PELI3,SNAI3,CDC37L1,FGF17,HBB,NEDD8,CXCR1,PTCRA,TRMT6,NDUFA5,CCL21,KCND2,IL34,DFFA,RASGRP2,LPXN,ST13,CD2,POLR2I,FBXO30,TIGD7,WWP2,RABAC1,UCKL1,RAP1A,ACAA2,BRMS1,PAOX,CD3G,KIF1C,GAS8,CHRNA7,CDKL2,NPVF,AKR1C2,IGFBP4,LMBR1L,OPA3,TAC1,TBCE,SPATA2L,IPP,NQO1,OXNAD1,BRI3,OCEL1,ADAT1,HEXA,TMED1,RBM23,AZIN1,PSME2,INO80C,ABCB1,HBE1,AZGP1,FGF1,JAK1,LBH,GTF2E2,MLF1,MAGOH,TBC1D10C,NKX3-2,CCL19,DHRS3,TNFAIP8L2,DEFB116,NDST1,DNAL1,KTI12,SMAP2,RAB3B,CDCA3,ATP6V1G1,MTPN,WDR77,FZD4,MEST,AAMP,TMEM213,MX2,GPBP1L1,ZCCHC10,SYN3,MFSD6L,LYG2,ZNF24,FBXO42,TMEM215,TSEN54,SERPINB10,LHX2,UBAP1,ZYX,CDC73,CYP27A1,S100A6,DYNC1I2,BTF3,MMP9,VRK1,ROPN1B,PGK1,HEBP1,PACSIN3,SLC7A9,ALKBH4,SNAP91,MYH2,DNAJC5,TMIGD1,KPNA1,CSNK2A1,PIWIL4,GRSF1,RARRES2,ATF4,CTNNBIP1,GNG7,GSTO2,KBTBD2,SUPT7L,JOSD1,P4HA2,OR4D9,AFTPH,LSM3,RS1,KIT,SLC39A7,SORD,SBK2,MCOLN1,PSMB5,ENPP4,CCT5,SMCP,AGK,FBXO32,ANAPC2,PRPF4,ZNF593,ARMCX5,RAB18,IDH2,FKBP14,CD58,AGER,IMPACT,CAMK2G,SRP54,TMX4,BUD31,CIB3,TACR3,PRMT2,CACNB4,RPL15,TUBG1,GHITM,TTC4,SCFD1,CCDC47,SHC1,OR4K1,PYGM,FGFR1,CAMK2N1,HCRT,CRYGB,PPP3CA,KCNJ11,CD200R1,CCDC127,PEX3,RCVRN,FAM89B,FRMD8,RFX4,ZDHHC14,PKNOX1,ADRB1,PCDHB8,RBM17,HEY2,TRAPPC1,NIPA2,RABL2B,PAEP,CLDN11,FAM199X,NPY2R,LRP12,RNASET2,SPTAN1,SLC35E3,HNRNPC,SETD5,PTPN1,ZBTB38,HECW1,TRIM37,NFIL3,PGS1,RBBP7,SLC25A21,RMND5B,ARMCX2,ACTA2,SIX5,TRIM21,PPARG,ARFIP1,GALNT12,SPR,SF3B4,IL20RB,DKK3,CRABP2,RPS23,DPP10,PRRC2A,CDO1,RAB11A,PPIL4,CCNI,ASMT,TLR9,L1CAM,FIBIN,WDR38,SNX20,DLX1,AKT1,APEH,FGD2,COMTD1,FNDC8,PSMA3,CCDC69,GALNT1,SOCS5,AK2,GSTO1,TMEM156,SPRN,EHBP1,MGP,MDM2,MRPL13,EXOC8,PFDN5,UST,GNRHR2,TOM1L2,LYAR,B9D1,NUDT3,CNP,RND3,PLA2G5,KLK9,ARHGAP1,DOK4,RNF141,KLHDC8B,TRIM32,CD99L2,SNRNP27,PRIM2,PDIA6,UBR7,SDR42E1,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,E2F6,GFM2,GDI2,MRPL23,ZNF207,EDF1,ATP6V0B,TMEM219,C1QC,TRIM3,TMUB1,POLR3H,ZNF671,SLC25A31,SLC17A5,RPS14,LIG3,LYPLA1,MEAF6,UGCG,CDK5R1,NRP1,NCKAP1,CNIH4,GLUL,LMO4,ATPAF2,KIAA0232,CLU,CCR6,TAAR1,SLAMF9,ZMYND19,XAGE5,APOBEC3A,ZNF397,ID4,SEC14L1,ZNF319,ARMCX1,UBE2A,CHRM4,CCT2,ATP6V0E1,UBE2D3,NHP2,TRIM23,NAIF1,IRF1,OR8B8,P2RY1,ING1,STRBP,CASK,GAL3ST1,OR4D11,LTBR,GRPEL1,ELMO1,TCP11L2,PRPSAP1,GABARAP,FGFR1OP2,HSBP1,DHRS4,SLC35A1,IMMP2L,MEF2A,RAG1,ENY2,SLC30A5,KLK3,SNAPIN,ZNF304,MRPL50,MRPL24,OSM,IL15RA,SLC38A9,MIOS,PPP1R2,FAM78A,RMND1,CYP11B1,PYDC2,GRM2,CTNNBL1,GALNT4,IDH3B,SENP5,GPAA1,JAKMIP1,ADGB,TLR3,EIF4H,ITK,NCR3,FAM8A1,LRRC69,SWAP70,HSD11B1,CYP39A1,MYL12A,GNRH2,CHDH,ATAT1,ARMC7,CIDEB,IPO8,TMSB10,ZBTB5,ZC3H7A,AIF1L,CCR2,DSTYK,TMEM123,MRPS23,FUNDC2,CSRNP1,SYP,ATG4A,ZNF862,SFRP4,RGS7BP,CDKN2AIP,FCN2,RER1,ISG20L2,GPHN,POLE4,HSP90AB1,TEX30,SEC61B,GPR65,BCL7B,TOM1,DNAJC22,EIF2B3,TMX3,HTR5A,TCF23,PAPSS2,GBE1,CHGA,APOO,BCS1L,SNX17,GPR137,NRSN2,SRRM5,TMEM144,TOP1,GCNT3,OPRK1,NKX3-1,F9,PGPEP1,ZNF740,NDUFS8,CYP2C18,MYO6,KDM4B,TMEM184B,ZNF287,ACAT1,GIT2,OAS1,NKIRAS1,CXCL3,GTF2B,RUVBL1,SDF2L1,RAB3D,LAMB2,SLC13A5,CLDN4,GPX6,POPDC2,GREM2,TGIF2,RDH10,PDCD4,LDOC1,GPAM,CREBBP,PRPF19,OR4Q3,HTR1F,TRIM54,RPLP2,CDC42SE2,ACBD7,FAM98A,ADIPOQ,ANKRA2,ERH,ALKBH5,UHMK1,CRTAP,LCP2,IK,CLDN1,ABHD6,METTL2A,TFCP2,AKAP14,NDUFAF4,CRYBB2,FAM162A,CTDSP1,CCNB1,SLC35D1,SMU1,RMI2,COL1A2,SAT1,CSGALNACT1,R3HCC1,METTL14,VAMP5,EDEM1,GNG2,JPH4,AMIGO1,PTS,TOR2A,MBL2,GTF2H2,MAP3K11,NDUFB4,RAC2,LCA5,STK24,MRPS21,PYROXD2,TAS2R40,LRP6,PARP11,SLC32A1,POR,ST3GAL5,IFRD2,ZNF501,CEP97,IL18,DERL1,ST3GAL1,CSNK1A1L,SOX2,STXBP1,KLC2,PAX9,PCMTD2,STOX2,ERV3-1,CD36,IRF3,MTHFD2L,DPEP1,UQCRH,PRKAB1,STAU1,STOML3,TSN,SLC41A3,SERINC3,KLK6,FKTN,DNAJC3,RNASEH1,TMED7,NOS1AP,BCL10,KCNMA1,MBD5,ADPRH,PDHA1,DUSP19,NME1,STMN2,RGS2,NR1I2,CNNM4,NPR2,CDK4,RBM7,TRAF2,KCNK13,ABHD4,PCDHB1,BRCA1,EWSR1,B9D2,TMEM204,PROS1,GPX3,MRPS16,ABHD14B,EED,MTRF1,ZNF592,DTYMK,TGFB3,TRIM24,MRFAP1L1,ACSL4,CIB2,YAF2,ELP3,CALHM2,GMPPB,LMNB1,BECN1,FAM219B,CCDC25,TES,OSTM1,CHMP2A,EMP3,MSMP,HSPA8,VMP1,CBR4,SLC19A2,GOLGA7B,TSPO2,OLFML3,SH3GLB1,THTPA,PREPL,RNF113A,EFNB1,IFNA10,DEFB114,MT1M,TFE3,COMMD8,ITGA6,CSNK1A1,PELP1,ADIG,NTN4,RTKN,FUT9,PHYH,IL10,UBE2V2,RPLP0,BZW2,OR10G9,TSPAN5,RINT1,KHDC1,NAT2,SPECC1L,B3GALNT1,CREB3L4,EIF3K,CD274,FABP7,BCAP29,ZBTB17,DDX39A,RAB40AL,AKAP12,IGBP1,SSU72,BLOC1S2,SNCG,SNAPC3,COX4I2,CDKN2C,CALHM3,LHFPL4,EIF4E,TRIM5,TMSB4X,PHYHIP,DYRK1B,FN3KRP,WIF1,ACADSB,SNX24,ISG15,OR10G7,STAT6,FGFBP2,ARCN1,EZH2,KCNIP3,INPP4A,AMT,RAB9B,SACM1L,VPS33A,CD226,CRBN,ZFP1,PDYN,B4GALT3,SNRPA,CMPK1,BEND5,CCNF,VAMP2,TRAPPC6B,WDR44,GPIHBP1,CTNNA1,RAB2A,SELENOK,STK38,TIMM10,WEE2,PCDH19,RAB5C,PNP,AP1AR,SMN1,FOLR1,RAB37,SLC6A11,C1QL1,IFI35,PSRC1,FBXO25,CSTF2T,CAV2,DERL2,TXNL1,TIMP1,PLEKHJ1,MLF2,ELMOD1,RPL23A,LYNX1,IL6ST,TMEM59,EIF4B,PPP2R1A,SMAD3,SLC25A4,PTHLH,MRTO4,AMY2B,RBMX2,NDE1,CD2BP2,TDRD7,HMBS,LDHAL6B,CCDC65,SNIP1,SLC4A8,LY6G5C,UBE2D1,ACTL6B,FAM168A,RAB1B,INHA,RPAP2,RGS5,OR5L1,ZBTB45,ABHD13,HRH3,SOS2,PIWIL2,SLC23A2,GYS1,PGM2L1,ROGDI,CDKN1A,GK2,FOXN2,RBFOX2,ELSPBP1,STX18,ORAI3,SLITRK2,MED11,CLIC2,SDHAF2,PPFIA3,OTUD7B,TCEAL7,GDE1,TMEM14A,GPX5,TRIQK,PCGF3,CPSF2,CDH8,MYEF2,PNPLA8,TAF5L,MOV10,NGB,UQCR11,GLT8D1,SLC43A2,ZCCHC9,TMEM91,CASP12,TEX12,HIGD2A,B3GNT2,TOP3B,GRIA2,LRRC24,MRGPRX2,DDX4,CAB39,LIX1,KLK5,SLC7A14,DDX42,PXMP2,ATP1A2,PPP1R16A,MT2A,GMPPA,CYB561D2,RPL6,SPRR1B,TUSC3,CXCL14,ADAMTS1,CLDN8,BNIP3L,KIAA0408,RNF122,NAPG,CREB1,SERPINA5,BICD2,TMEM177,FMO2,GLIPR1,SQSTM1,RPP25,RAN,RBM12,BRD9,LCN9,HAND2,PGR,POLR3B,NPY5R,CDH13,CXCR4,HSPA14,GTF2F2,DLG4,PAFAH1B2,OR2H2,CCL17,KIAA1191,KCNH1,SLCO1A2,KCNK10,ZNF609,TMCC2,SELENOS,MANSC1,GJB2,WDR3,KRT7,PLEKHA8,TMEM106C,SRP14,NUS1,ACTR2,TAS2R5,TMEM203,OR4F6,CRYBB3,APLN,TMEM164,ACP6,SYNJ2BP,PLAGL1,PAPOLB,SESN2,TRAM1L1,RFXANK,KLHL15,GCA,ZNF576,UPF3B,RABL3,ISCA2,EHD1,MPV17,CHST1,FCHO2,TRAM2,PPP1CB,DNAJC8,TNFSF18,PPDPF,FAM107A,RNF167,CRYGD,RAB33A,SPTBN1,TNRC6C,RNASEL,CHI3L1,UTP23,GNPNAT1,GIMAP2,TOMM40L,FERMT2,EIF3J,WWP1,RHOJ,CBLN4,CD47,S100A8,HIRA,IFNG,JUN,TMEM50B,ZNF687,OGG1,CCR3,SUMO3,OPHN1,PTGER1,CMAS,RAB23,SFT2D2,CCL8,NAA60,CAPZA2,SLC35E1,RB1CC1,RFTN2,TPPP,PPID,YPEL5,ATP6V1C1,GGCT,RCBTB1,HNRNPA2B1,TAPBP,MAPK1IP1L,PLA2G15,OR2A25,STX6,FANCG,PRKAG1,HNRNPK,PAFAH1B3,NFKB1,SCD5,MAFG,ACAP2,LHFPL2,FOS,DYRK2,EGLN3,CLDN22,OS9,RPL26,POMP,OAT,MRPS28,RIOK2,HTRA2,NDUFAB1,JAGN1,SNAP29,TYW5,CBLN2,NUDT12,RPL27A,NEUROD2,BABAM1,METTL15,PGRMC1,PTK7,COX20,DHX38,GPR171,COX8A,LGALS8,USP8,TMEM147,CNDP2,PPFIA2,FBXW11,CINP,BCL7C,IL1A,OR4D6,THBD,CREG2,PCYOX1L,PLD3,AGPAT5,DNTTIP1,HR,LRRC3,DKC1,ARPC3,FBXO44,NXT2,CHST2,HNRNPA0,IKZF5,FZD3,CD247,RHOBTB1,CDAN1,OPRM1,SPRED2,DDX23,PCNA,PDE1B,PIK3R2,NDUFS6,TMEM126B,CTSC,OR10A4,ELMOD2,USP15,LPAR2,FKRP,CNRIP1,APOBEC3G,TWIST2,NTRK2,PABPC1,GNG12,ARG2,DNAJB9,RNF144B,SIAE,ISX,TOMM6,GAMT,RTN4,GLRX5,GNAZ,NRN1,MAPRE1,CTXN1,GNG10,MUL1,SMG9,SEC22C,METAP2,MME,ZFAND2A,TXNDC12,RWDD3,CENPW,ATG4C,SNRNP48,FRRS1,GFPT1,SDHB,NEGR1,FDFT1,SIT1,CCDC160,RPA3,MOXD1,EPHX1,CXCL13,ABHD5,CKS2,RORB,CLDN3,CLDN24,ADAM21,RLIM,PTEN,DEPDC1B,INO80E,CRLF3,UCN,MGAT5B,THAP7,UAP1,NDUFAF3,CHPF2,IER2,PPP1R1B,RND2,COMMD3,BMPR2,SCG3,OLFM3,RASD1,CCS,NLRP3,ILDR1,SHISAL2B,SCGB1D1,OXSR1,ILF2,ORC5,ZNF365,BAG3,KDELR1,TOM1L1,RRM1,RBM22,KRAS,RPS16,CNTN2,ASNSD1,NR2F6,HERC4,DKK1,PSMB1,CRIP1,ZMYM3,SUFU,MTA2,CCDC86,MRGPRX3,FBXL19,LAPTM4A,CHIC2,CHCHD4,SLC38A7,PGGT1B,KCNC1,OXTR,METTL21A,POP5,PSORS1C2,G3BP1,CHAC2,MFSD5,FGFBP1,MRPL18,NUF2,TMEM101,HINT2,OR13C8,SLC16A1,PCDHB13,RPS27A,DSTN,DAPK3,RAPGEF5,ELOVL7,DBT,TPD52,FBXL14,RHEB,DHX15,OVOL1,NPPC,PSMD4,RPS7,GRAP2,RAB27A,GPX1,TRIM15,RELL2,SLC6A6,SLC30A7,TCF19,CCDC134,DDX46,PDHB,MAT2B,ZNF664,MLC1,OCRL,XCL1,BBS5,RPS6KA4,GANAB,LARP4B,OR2Y1,STX11,SERPINA1,PMP22,SCLT1,MRPL11,DAAM1,LRRTM3,ANKRD34B,LSM10,HSPA13,NPSR1,LMAN1,SH2D1A,UBB,SLC11A2,PPP2R5E,TOR3A,GLRX,CBLL1,UBA3,SRSF7,EPCAM,PCDH17,TAGLN3,STAT2,SAV1,IL22,PRR3,RPL7L1,CSTF3,HENMT1,CSGALNACT2,ST6GAL1,REEP3,BFAR,TOMM22,TMEM179B,IRAK4,IMP3,UBL3,TMEM30A,AFAP1L2,COMMD6,KCNJ3,B3GALT1,GNPDA1,SNX22,SFXN2,CST11,FASTKD5,NCDN,GNAO1,CYP21A2,MRPL34,NDUFB6,TMEM117,TMEM170B,TMEM167B,HSD17B6,PLCB2,MAP2K1,APOBEC3F,FPGT,LRRC3B,EIF4A2,OTX2,MAGEH1,PRDM4,FEZ1,COPS5,STAT5A,ADAMTS10,MRPL20,EP300,AKAP8L,RNF8,PEA15,LAMP2,TMEM237,CGB8,TMEM45A,RNASE1,NLRP9,FAM43A,LLPH,GSTP1,CCL2,PPM1K,OR8B12,AR,IFI6,EFNA3,TPM3,SNRPB,ELOVL1,MORC2,SSR2,SOSTDC1,RIT1,OR10P1,GPX7,CHRNB2,PTPN4,HP,VAMP7,CTTN,STOM,CLLU1,RPL23,SPIN3,ANP32A,FBXO7,RABGGTB,SLC2A3,SEMA4C,CYP2C8,METTL22,ASZ1,CAPN1,USP3,TGFBR2,CEBPG,CDNF,TNFRSF1B,TIMP3,PPP3R2,PRSS12,PRMT6,PMM2,TTL,TMEM70,MPDU1,VAMP8,PPAN,IL2RA,SF3B5,RCL1,KLHL24,GABPA,FKBP8,PPP2CB,ZNRF1,CHST13,CLEC18A,SMAD1,AQP2,SPC24,CDCA7L,MRPL22,SS18,CD1C,RAB19,UMPS,IFIH1,NUDT7,FCGR2B,BIRC2,MTM1,EPS8,RFXAP,UPK1A,HOXC4,CHCHD6,SIAH2,POLR1B,CER1,MCM4,SCNM1,DCTD,FAM177A1,STARD4,THOC2,ORC6,FLOT1,NR2E1,DROSHA,KLHL22,MAVS,UBP1,IGF1R,FAM219A,CX3CR1,SLCO2B1,PDAP1,SOX14,CEP19,CHMP4C,ODAM,VDAC1,CLPB,FEN1,KLF1,ASB7,PRKACB,GLRX2,LANCL2,APOBEC3H,ADD1,JKAMP,CBR3,CLEC2B,SEPHS2,CHKB,CCNY,ELF5,CLDN12,GPR176,PKP4,SCML2,DNAJC19,VGLL4,FCGR1A,GSTM5,ERAS,PLEKHO1,MYBL2,ZNF326,CRHBP,CNOT2,OTOS,ACBD6,RNF34,OR10A6,OR4D2,KLF4,COPS7B,DENND2D,LRRC8B,ETF1,TRIM68,ATG7,NFKBIA,NPW,TUSC1,PREB,FAM53B,PRDX1,TAF10,PARL,DHRS13,UBE2W,TSNAX,POLR2B,LRRC61,UBIAD1,GTDC1,ATP6V1A,TMEM59L,EGFL7,HLF,SERPINC1,ACP5,GPM6B,REG1B,FBXO22,RFC3,SLC7A8,FAF1,VEGFA,TP53INP1,IQCK,AVL9,DECR2,DTWD1,ATXN10,TBC1D13,ASTN1,SOD1,NCBP2,SMPD2,CCR1,REN,GNPDA2,TMOD2,PTPN11,SOBP,NAPA,NOTCH2,CRAT,TM4SF19,SLC25A12,HMGCS1,CLCN6,AK3,PFDN2,LTB,TCEAL1,USP16,TMED5,HARBI1,SHOC2,HDHD3,DRGX,PSMA1,RPL32,DDRGK1,RPL27,PPP1R1A,MSTN,RNF148,PRICKLE2,MTF1,PTH2,DIO1,VGLL2,SLC16A10,SYNCRIP,SLC35F2,TRMT112,CLDN9,KIAA0513,SEMG2,CCNH,UBASH3B,POLA2,POLB,MNS1,CSH1,UBL5,BTN2A2,IFNB1,LTA,MRPS9,ABCG2,UGT1A1,FAM83C,KANSL3,TOR1B,SPSB3,PIP4K2C,STUB1,KLF9,TMEM41A,IL1R2,FAM181B,NKIRAS2,ACVR1C,SNRK,TEX264,AVPR1B,ST7,TRAK2,SERPINB1,UBLCP1,SRSF2,GSTA1,DDX50,RPRD1A,GTF2H5,SLC25A10,HINT3,VRTN,ZNF821,PLS3,ST8SIA5,CYP1A1,TNKS,SLC22A17,STK4,SPON1,PPP2R2C,BST2,ROMO1,CRYAB,PPY,DNAJC2,GNB1L,ATP1B3,ZNF473,SELL,KIAA1143,GNL1,NAB2,FXYD6,ZBTB25,CD28,TLR10,WDR82,OR4S2,TAF7,APOC4,CYTH2,RNF11,SYNGR2,TMEM11,FAM169A,TNFAIP1,S1PR4,APBB3,MCMBP,SEMA5A,AGTRAP,CRADD,PPP1R3C,KCNAB1,CNOT6,REEP6,MATR3,CHPF,LAMP3,TP53I3,DPM2,RNASE6,KDELR2,DAP,DDX1,RPS26,RNF40,BRIX1,IRGQ,CFL1,KLHL3,UBE2H,FARSA,EXD2,KBTBD6,PTPMT1,ZNF704,OXCT1,ENO2,PSENEN,SLC2A8,CD86,PNMA5,MANBAL,SFRP1,ELF1,WSCD1,TMX2,HTR1A,METAP1,ZC3H11A,CCL27,G6PC3,RANBP6,SLC25A39,CD14,PRR5L,CYP2R1,SLCO1B3,GOSR2,FGF23,MKLN1,CCL28,ASF1A,PPP1R8,SHISA2,KCTD10,RAB35,MAB21L1,FEM1A,CD40LG,SMG8,TMEM50A,LILRB4,TAS2R39,MYC,VPS26A,CMTM6,EEF1E1,TCF21,CNKSR3,CASC3,SLC6A3,HEBP2,SP2,VAPB,PNMA1,CALML5,TOP2B,PSMG3,GPR173,OR5V1,TUSC2,SEC23A,TIRAP,GEMIN8,MYL6,RPS9,AGA,CD63,LCN8,CPSF4,TMEM174,MORF4L1,NLGN1,TTC23,PCBD1,AGR2,CACNB3,KBTBD3,PCSK9,PSMA6,PARM1,DNAJC24,AKAP1,CLEC1A,ALB,CCM2,SLC35F1,PSEN2,SNX1,FTH1,IL2RG,PIWIL3,DUSP10,BACE1,SLC38A1,SLC48A1,CDC42,TNFAIP8L3,SLC25A26,SYK,VPS16,ACO2,CLN8,TTC33,C2CD4C,OR2AT4,RPL39,TESK1,DVL2,TMEM108,SURF6,BRD3,FAR2,PRKCA,TFPI,PAAF1,UCHL3,TRAPPC4,EEF1A1,GAS2,MAP3K21,WRAP53,MMD,KLHL26,BET1L,HMOX2,HNRNPH2,COX11,CLIC4,NPTX1,AHCYL1,ALDH1A3,IZUMO4,ADM2,FOXP1,SLC4A10,HOMER1,PSMB9,PDE8A,TRIM6,PYGB,ENC1,KCNJ8,SAMM50,EFHD1,C2CD2,ADIPOR2,LAP3,SLC20A1,ALPL,RCCD1,EXTL2,API5,LRRTM2,TST,DGCR8,RNF5,RPL9,ZMAT2,NT5C2,DOLK,EHD3,MRPS18B,ST3GAL4,DNAJC30,P2RY12,FKBP1A,SRXN1,SPRYD4,KCNS1,TPH2,PHACTR1,SAMHD1,CRYM,DNAJC4,EIF3D,RBP5,CCDC92,AKT3,POLD4,MAN1A2,ERVFRD-1,GRB10,CSNK1E,SKA1,CHMP2B,ELOVL4,PAK6,RBBP4,COX6A2,POLR3GL,UBTD1,TMPO,MAD2L2,ABCB9,FAS,ATF1,COX16,CUL3,PLSCR3,ARMCX3,OR5A2,CTDSP2,RPL10A,FAH,CAMSAP2,ACVR1B,SDC2,NPC1L1,KLHL9,TIMM8A,CARHSP1,ACTR1A,LAT2,FITM1,SNX14,AIFM1,COQ10B,POLR2G,RAD21,RAP1B,AKAP17A,TXNRD2,DNAJB4,C2CD2L,GLRA2,RPL29,MRPL53,HDAC3,PI16,BHLHE40,MAP1S,FABP4,COX4I1,MPHOSPH6,TOMM40,GREM1,LRRC4B,GDPD3,ARPP19,ANAPC4,ERLEC1,CEP85,SRPRB,FGF3,DRG1,SDCBP,MED23,USP13,TMEM42,SNX33,NDP,SMNDC1,NEURL2,PDP2,CNTFR,KRT222,SNX12,POLR2D,ARPC2,CLEC7A,APPBP2,GPR146,OPTN,KCTD11,PID1,NECAP2,SRSF4,EXOSC3,ATXN1L,SH3BGRL,IL7,ATP6V1E2,ZHX3,ENHO,GINS3,MYL12B,CALU,AIF1,SRSF10,HBEGF,TMEM60,CHN2,OR1F1,RPS3,LRRC20,EGR2,HAX1,USP30,RAD23B,FOXJ3,ORMDL3,CTNND1,KPNA2,LCN12,FAM91A1,SMYD3,DDIT4,RAB3A,LUC7L3,HHIP,MAP4,LGALS3,NMBR,CA8,KBTBD13,OR10Q1,YIF1A,TSPAN11,MND1,GGPS1,IPCEF1,FOXI3,UTP6,OR1S1,SH2D5,HMGA1,C1QTNF1,HSD17B11,PPME1,ZNF177,ZNF652,ZNF267,IDE,TTC8,TFRC,AUH,PLCL1,ICAM1,MTMR2,YWHAH,FAM187B,MRPL49,GABRB3,ADAMTS20,GFOD2,DUSP22,SOD3,KCTD12,UQCRQ,RPL12,CD83,DNAJC7,CCT8,TMBIM6,LSM2,PABPC1L,ZNF189,EEF1B2,RBM15B,MIF,ACTR3B,ZNF22,TFDP2,C1D,TMEM45B,BCL2A1,RGMB,ZNF688,SPINT2,HRH2,AP2A1,APTX,DGCR6L,WNT10B,HMX1,SPSB1,RBBP9,FBXO11,NTNG2,ETFB,VIP,LRRC8D,FCER1G,CYB561,BET1,IRF8,KPNA6,RWDD4,TOX,PTRHD1,HSD17B1,TMED4,TBC1D17,HEXIM2,SLC25A46,FTSJ3,TSEN34,SYNDIG1,GSTM3,PPM1B,PKIA,TRIM35,TRAFD1,OSGIN2,LIMS2,MZT2B,GPC4,NECAP1,HBA1,GADD45B,STX7,SENP8,MGST2,KIN,KRTAP3-1,TAX1BP1,AP2M1,PRDX6,INMT,NFKBIL1,CRELD1,PPM1M,TP53,TNFSF12,RDH12,ZNF790,TAX1BP3,ARF4,SCGB1C1,GABPB1,EIF1B,MT3,SERTAD3,ZNF250,OR10A7,PSMA4,DNASE1L1,GABARAPL2,PML,DAG1,ZBED3,SETD7,PPIF,DUSP6,MTHFS,MAF1,TXN,CYB5D2,RPS12,POP7,STYK1,LYPLA2,SNRPN,TSPO,DCAF4L2,RPRD1B,RHBDL3,TRMT61A,CAMP,COX5A,THNSL1,SLC1A2,PHF21A,CYP11B2,FBXL7,LBR,CELA3B,OMG,GPD2,RPL24,CRYL1,SERPIND1,CHST7,ORAI2,GNPTG,ENO1,OLFM2,RGS6,CSTA,TBC1D19,CLSTN3,RASL11A,PRDX4,SLC25A14,NUP35,MECP2,ZNHIT1,TFPT,ELOVL6,ALOX5AP,ADK,G6PD,F11R,FTHL17,WDR55,RALA,EBLN2,NAA15,SYBU,EXOC5,SERPINB6,RNF128,PTGES,ACADS,TLR7,GAPT,VASH1,PPP2R5A,RHAG,IL12A,CCR5,SAR1B,CAPG,OGDHL,TLR1,ZBTB16,ANAPC16,CHORDC1,PAPOLA,DHRS1,HCST,FBXO34,BRMS1L,OR5B3 |
| 8.518e-08 | -16.28 | protein maturation | biological process | GO:0051604 | 483 | 196 | 18204 | 5365 |
PDIA3,ATG4A,GALNT2,GRPEL2,VSIR,NAA15,PPIC,GRPEL1,CCT8,DNAJC4,TESC,PFDN5,KLK6,SCG5,H2BC1,CLU,DFFA,MME,DNAJC10,STUB1,P3H1,LIPT2,CASP4,SPCS1,DNAJC1,HSP90B1,CLPX,PRSS37,NPPC,GLRX5,PRSS12,PPIF,PPIH,DPP4,YIPF5,BOLA2B,NLRP3,NAA11,FKBP4,DNLZ,TBCEL,BOLA3,LMAN1,THBD,TTC1,RP2,DNAJC7,WDR83OS,CIAO1,SPCS3,SPPL3,FKBP8,PFDN1,F7,DNAJC2,FKBP10,SEC11A,ISCA2,PSEN2,BACE1,TOR1B,BAG2,PPIL3,SERPINH1,HSPA8,PPIB,TOR2A,PPID,PTGES3,CHORDC1,PSENEN,NDUFAB1,TBCE,SRGN,AASDHPPT,PDIA6,B2M,NCSTN,IKBKB,MYRF,CHCHD4,RCE1,MKKS,HSPB6,UNC45A,CDC123,METAP2,DNAJB4,IFI16,PGK1,TCP1,CAPN2,CCT5,SLC30A5,NAA35,DNAJC5,TMEM208,CCDC47,SPCS2,LTO1,CYFIP2,CRTAP,NUDCD3,AANAT,BAK1,NAA16,CALR,METAP1,EP300,APH1A,CCT7,CREBBP,PDRG1,DNAJC24,FKRP,PDIA2,MPDU1,SDF2L1,BMP1,TTC4,FKBP2,BAD,PARL,HSPA14,AHSA1,DOHH,CCS,TSPAN15,PCSK9,CCT2,PFDN2,FKBP1A,RIC3,HSPE1,CISD1,ATG4C,DNAJC25,ERO1A,PPIG,BAG3,AIP,TSPAN5,IL1R2,PRCP,PFDN4,CSNK2A1,CPE,PPIA,HSPB2,HSPB1,CRYAB,IFT172,SELENOF,ERP29,GP9,ACTMAP,PMPCA,DUOXA2,MMP14,IMMP2L,DNAJC19,STOML2,SPON1,ST13,NAA50,HSP90AA1,REN,HSPD1,PCSK2,DHPS,ATP6AP2,HYPK,YAE1,RUVBL2,NAA60,FKBP1B,SNAPIN,TAPBP,HSP90AB1,CMA1,F9,FURIN,HSPA13,PFDN6,PRDX4,DNAJB2,DNAJC3,PSEN1,FXN,ENPEP,HM13,DNAJB6,HTRA2,CDC37L1,HSPA5,ZMPSTE24 |
| 8.553e-08 | -16.27 | protein-containing complex organization | biological process | GO:0043933 | 2067 | 713 | 18204 | 5365 |
SF3B6,TM9SF4,KRIT1,SNRPB,TRIM21,ANGPT1,SMARCA5,PPID,CLDN14,CALY,SLC25A46,SRC,NRDE2,PTGES3,EXT1,METTL22,PRKRA,PDCL,MED17,NBN,EIF3K,TFIP11,IFI16,PET117,LPXN,CELF6,MIR29A,TMEM199,TRAPPC4,SMARCB1,MECP2,SIGMAR1,PRMT6,COX17,FCHO2,NDUFA5,MED30,PCGF3,MACROH2A2,SETD5,COX19,CLU,KCNG3,CLTRN,KMT5B,TAF9,COL1A2,GPAA1,CRTC2,HMGN4,RNF40,NINJ1,H2AZ2,TXNL4A,HP1BP3,VPS16,CD2AP,FGF13,ALOX5AP,KCTD16,LRIF1,KCNJ8,SSNA1,NDUFB5,SRPRA,SNRPD2,PML,CBR4,TRAF7,MAP4,SNAP91,GNMT,LUC7L3,PALS2,MTA3,DMAP1,CBX3,MRPS7,HSPD1,VPS33A,MORC2,KCNA2,OTX2,CFL2,NDUFB6,COPS7A,SNRPB2,STOML2,KCNF1,TRAPPC1,COX7A1,AQP4,UBE2B,RTN4,DNM2,NOPCHAP1,FMC1,H3C1,NDUFS3,SRSF10,RPLP0,RCBTB1,SNAPIN,BAP1,AQP2,MED29,KHDC4,SIN3A,CHMP2A,INO80E,SDHAF2,H2AC6,LSM4,PRMT5,GABARAP,NOP53,GMNN,ZMYND11,LMNA,GPX1,H2AC7,COPS7B,SLC1A2,VAMP1,BOK,HSD17B10,WDR77,EIF3D,CATIP,UQCC3,EP300,DR1,RPSA,GEMIN8,RRN3,RIC3,SKP1,SS18,PHF21A,NUP153,H2AC4,CREBZF,HPF1,TMEM126B,ABCE1,ACACA,TUBA1A,SMCHD1,BAD,GSK3A,EIF3G,ASF1A,CAND1,USP3,JAK2,STXBP1,FBXL19,MIS12,MED31,MORF4L1,LRRC8A,TRIM27,EYA3,UGDH,POLE3,DNAAF10,TFPT,DNAJC2,HDAC11,HUWE1,PIWIL4,CHMP1B,RRP7A,NDUFAB1,TBCE,SRSF1,VPS4A,COX10,MITF,VPS72,EEF1AKMT3,BCS1L,TAF7,SRPRB,RPL23,ZNHIT1,CALHM3,GABARAPL2,LYRM2,RNF20,EZH2,EZH1,COA1,RPS5,H2BC14,CAPG,MKKS,CHCHD4,EGR1,SRP54,RAD21,PYCARD,BRIX1,ZNF304,STXBP6,PREB,H2BC1,INO80C,ZDHHC8,KCTD11,BCL7B,HMGB1,SNX14,TRIM6,VAMP7,ATL1,H1-1,ETF1,TRAF2,CBX5,TRAF1,H2AZ1,RAF1,RBBP7,ATPAF2,TMEM126A,BCL7C,RPS28,CGGBP1,PPIH,H1-6,NEFL,PRKCA,OGG1,PSMG3,RAG1,H2AX,CIDEB,USP16,SPHK2,PPAN,CFDP1,RPF2,KCNA3,VAMP2,DNAL1,PSMD10,PWP2,KDM4B,UBE2A,SNAP25,H2AC13,UQCC6,NAA50,HSP90AA1,EED,MED21,USP15,EIF2S2,NDUFA12,RPS6KA4,SNIP1,CDK1,SSBP1,GATAD1,KCNJ2,SLU7,FAF2,SELENOF,MYC,RPL23A,PHF13,PEG10,ZNF207,ARB2A,RPS27L,CLDN1,SNRPG,APOBEC3F,BRCA1,LIX1,TAF2,NUDT5,ZMPSTE24,IFIH1,MSRB1,KCTD17,TMEM70,HSP90AB1,NAA60,MEAF6,VCPKMT,ARPC2,PFDN6,MCOLN1,WASF3,KCTD15,CREBBP,WDCP,JCHAIN,PIWIL2,TPPP,DDIT4,VPS4B,FARSA,NPM3,DYRK1A,EIF2D,EIF3J,WASL,SOX2,TRIM37,NDUFA1,NCK1,RING1,TWNK,GTF2H5,SNRPD3,KLHL12,DPY30,SRPK2,PICALM,PYM1,NDUFA2,PRM1,BAZ1B,TADA3,NFE2,GPX4,NAP1L3,SETD3,SNRPE,DIRAS3,HNRNPC,UBN1,SNRPA1,EEF2KMT,MAP1LC3A,PRKCB,NAP1L5,MACROH2A1,COIL,H2BC11,NLRP6,CCT2,HSD17B8,COX14,TRAPPC2L,POMP,UQCC2,H2BC17,NDE1,NDUFAF6,CHTOP,NDUFB10,H1-3,ADRM1,SUPT4H1,GFM2,CENPW,NUP107,CBX7,APEX1,NDUFS2,NDUFAF3,COX20,BMERB1,RCCD1,PIK3CA,TIAM1,TAF10,TCAP,NLE1,NDUFB8,STX17,NIBAN2,NDUFAF4,TIMM21,STMN2,DEK,COX16,H2AJ,TCP1,PRKACB,KCND3,SSRP1,CUL3,SETD4,WDR19,METTL21A,GTF3C4,SATB1,CAPZA2,SAMHD1,VRK1,MTA2,RRM1,EIF3E,AP2S1,NDUFB4,NSMCE3,HIGD2A,TMEM170A,GTF2E1,MED22,ALKBH4,APOBEC3C,HDAC6,HSCB,SGF29,KCTD3,FOXA3,CD40,MED10,NLRP1,MRM2,HR,MED23,VMP1,ASIC1,MED9,TRMT112,TRIM32,PARP2,KCTD10,RS1,APEH,SLC2A1,ACOT13,XRCC5,PIAS1,VAMP3,PRPF31,FKBP4,TACO1,TBCEL,CENPP,H2AC1,SNAP23,APOBEC3A,PIH1D1,LRRC61,ATP5F1D,SPMIP6,WBP2,ARL6,EHD3,CLXN,H2AC25,GCFC2,NHERF1,DAPK3,SMN1,SMARCE1,SNAP29,LMNB1,SF3B4,PRNP,FOXP3,ACTL6A,DDX39B,PADI2,CHMP1A,BAHD1,LAMP2,DDX1,UBE2K,G3BP2,IMMP2L,UBE2S,LPCAT3,AQP11,EHD4,NACC2,RPL10,HDAC3,MLLT6,SMARCD3,GTF2A1,MED27,TAPBP,BABAM1,OTUD6B,CHMP2B,CRYZ,SAR1B,PAX6,CCDC65,SSBP3,TPPP2,SMYD3,FKRP,PRND,CFAP73,KCND2,AIFM1,FAM107A,CLP1,MIR182,TAPBPL,TOX,RBBP4,SIRT7,CALR,NSG1,BRD9,ENY2,KIF2A,PSMG2,PHF1,HIRA,HIGD1C,ANP32B,FAS,ATF1,PLA2G5,KCNS1,TAF11,TSG101,PHC1,TFG,USP39,DLG4,RPS15,JADE1,RBMX2,PIP4P1,HOMER1,HSPA8,LARGE1,PCGF2,GEMIN7,ZNHIT3,EHD1,PCGF6,SOD2,EPOP,TUBG1,SLC7A9,MAEL,TP53,STK4,KCTD12,MDM2,ACTL6B,DDX23,CD247,DSTN,CHMP4C,RBM15B,COA5,CHMP5,PPP2R1A,DDX46,MAPRE1,SUV39H1,CD3G,HELLS,ATAT1,LHX2,B2M,CCSAP,PIWIL1,GABARAPL1,SDHAF4,APOC2,CDAN1,SAMM50,CDC123,DET1,MZB1,IL1RAP,GTF2A2,KDM2A,MED11,TOPBP1,PFDN5,HFE,CXCL12,BCL6,HMG20A,SLAIN2,PHB1,MID1IP1,OIP5,RUVBL1,PDIA3,TESPA1,SF3B1,NDUFAF2,CAPZA1,CX3CL1,HAUS2,SHMT1,ACTB,HMGA1,CSNK2B,TIFA,IRF4,H1-5,AIF1,ALDH1A3,KCTD9,TPPP3,SNRPD1,NLRP3,COA4,H2AB1,PPM1D,SDHAF1,RB1,NUP35,LRRC8D,CD2BP2,TNFAIP1,PRPF18,TRAPPC6A,TAFAZZIN,CASP4,RPL6,EID2,SDR16C5,NDN,RBM5,CDK9,TSPYL4,MED4,TOP1,RIOX2,SUPT5H,ZNF518B,CFL1,STK3,SRSF12,SETD7,TSSC4,HEY2,NDUFB7,MAP1LC3B,SHPRH,BCL10,MIF,NDUFS8,CRYAB,AGO1,NUPR1,FERMT2,PSMG4,IL2RB,DDX42,RPS14,KCNB1,FAM50B,ADD2,KCNC1,RPL10L,NDUFC2,MYD88,NTMT1,H2BC9,MDC1,RUVBL2,ING2,AP2M1,VTI1B,H1-10,KANSL3,FURIN,THG1L,ADRB2,DDX4,HCFC2,ZNHIT6,SLC31A1,MBD3,MAT2A,THAP7,RNF8,SF3A1,NAPG,DHX9,VAMP8,CHRAC1,MSL2,LSM2,RERE,RLIM,LRWD1,GTF2B,DLG1,SF3B5,MTRF1,BANF1,NAPA,LRRC8C,FMOD,DICER1,SNAI2,BECN1,TRAPPC3,SART3,SOX9,VTA1,VIPAS39,NUCKS1,PRMT2,HDAC5,STPG4,ING5,PRPF19,KDM1A,BUD23,MIR29C |
| 8.589e-08 | -16.27 | peptidase complex | cellular component | GO:1905368 | 121 | 63 | 19108 | 5553 |
SGF29,PSMD7,SPCS3,ZFAND2B,CAPN2,PSMB7,SUPT7L,PSMA3,CAPN1,PSMA1,SF3B5,PSMA5,F7,PSMB5,HSPB1,TXNL1,PSMD14,PSMB11,RAD23B,PSMB1,TADA3,PAAF1,GPAA1,ZFAND2A,PSMC5,PSMA6,PSMC3,PSMC4,TADA1,PIGK,FCN2,CRADD,PSME1,SPCS1,PSMD6,HTRA2,SEC11A,SUPT3H,THBD,PSMC1,PSMB10,PSME2,PSMD3,SPCS2,PSMB2,TAF10,UBE3A,PSMA2,TAF5L,PSMB9,PSMD10,ENY2,TAF9,PSMD4,USP14,ADRM1,PSMB3,PSMD1,MBL2,PSMA4,PSMD12,PSMB4,PSMB6 |
| 8.599e-08 | -16.27 | MED31 (mediator complex subunit 31) | protein interactions | 51003 | 122 | 62 | 19454 | 5460 |
SMAD2,MED10,RFC5,HMOX2,CACNB4,MED22,POLR2B,GADD45G,GSTM4,ERH,ELMO1,MED17,MOB4,NFKBIA,PAFAH1B3,ANXA7,RPA2,MED23,FBXL19,MED30,CDKN1A,MAFG,CDK7,ZSCAN1,LYPLA2,MED11,EEF1G,FBXW7,SAT1,MED13L,RBM23,MED4,HSPB1,MED27,MED21,MED29,AGR2,PRDX1,MOV10,FAM118B,CCT7,POLR2I,WDCP,POLR2G,POLR2C,POLR2D,CPE,BIRC5,CDK8,UBE2B,RPAP2,EGR2,RAF1,MTA3,SERPINB9,MED9,PFDN1,SMN1,ZBTB45,KRAS,ORAI2,PQBP1 |
| 8.633e-08 | -16.27 | C15orf48 (chromosome 15 open reading frame 48) | protein interactions | 84419 | 135 | 67 | 19454 | 5460 |
TMEM70,NDUFV2,COX5A,STOML2,ATP5PD,NDUFS8,HEBP1,COX20,ACSL4,TIMM8B,COQ8A,RAB35,NDUFB4,OCIAD2,NDUFA12,CCR1,CYB5B,DHRS7B,NDUFS3,NDUFS6,HINT3,GLRX5,LYPLA1,ATP5PB,NDUFA2,MTCH2,RDH11,CHCHD2,SLC16A1,CLPB,GNG5,COX8A,UQCC2,ATP5PF,SFXN1,FIS1,BAX,FBXO7,SLC25A1,NDUFAF2,PMPCA,IDE,ROMO1,CHCHD3,UQCRQ,NDUFAF4,TAMM41,TXN,CPT2,TIMM21,ACAT1,UQCRC2,CYB5R3,ACACA,SLC25A3,NDUFA5,TIMM23,ATP5PO,COX6C,SAMM50,NDUFAF3,POLDIP2,NDUFS2,COX17,ATP5F1E,MAIP1,ATP5MK |
| 8.715e-08 | -16.26 | TMCO1 (transmembrane and coiled-coil domains 1) | protein interactions | 54499 | 175 | 82 | 19454 | 5460 |
ATP5PB,CCDC47,DDX39A,MGARP,PPP2R1A,STIM1,RPN1,PRKAG1,RAB1A,TMT1A,LPAR2,TMEM147,KRAS,RAB3B,PSEN1,RPL17,RIGI,RNF26,LAMP2,RAB5C,LAMP3,CCR6,DDRGK1,SLC2A1,ESYT1,PTPN1,CD274,DUSP6,HSD17B11,CAND1,FZR1,RPS10,RAB1B,EGLN3,RBM42,RAMP3,NUP35,PGRMC1,OTULINL,YIPF5,SEC62,CDC42,DUSP22,ST7,RPA2,SSR1,GRM2,GPR35,SLC25A3,CYC1,RPA3,TMEM106B,VIPR1,DERL1,HSCB,UFL1,PDHB,STAU1,SSR3,PXMP2,CLDND1,STX7,GPR17,SYP,RHOB,ATP1A1,UBE2H,CCNF,UQCRC2,LMBR1L,S1PR4,SEC61A1,SERINC1,SYNGR1,SEC61B,SLC1A1,RAB14,LAMTOR3,APLNR,UQCRQ,VIRMA,ESR2 |
| 8.715e-08 | -16.26 | TXNIP (thioredoxin interacting protein) | protein interactions | 10628 | 175 | 82 | 19454 | 5460 |
ECD,TRAF6,SLC2A1,CDKN1B,DNAJC7,WWP2,SIVA1,GAPDH,XPO1,COPS5,CSNK2A1,NOP58,HSP90AB1,MAGED2,PIK3CA,PLS3,TUBB4B,RPN1,HSPA13,SART3,TXNRD1,TP53,PPP2R1A,TUBA1A,EEF1A1,KPNA2,RUVBL1,HUWE1,PSMA5,PSMA1,ZBTB16,PSMA2,HNRNPDL,GTF3C3,S100B,PDIA6,ZC3H11A,PCNA,RUVBL2,TXNIP,DCAF16,CCT2,NLRP3,RGMA,ATP1A1,CDC73,HSP90AA1,AP2A1,PTPN11,MCM3,PRPF31,TUBB,TXN,PSMD4,ESR2,KBTBD6,SCML2,HOMER1,CTTN,ZBTB33,DDIT4,FAM91A1,RPS20,ADNP,WWP1,HSP90B1,TOX4,LUC7L3,EIF4B,UBA52,SAP30BP,STK38,FBXW7,KDM1A,GTF2I,HDAC3,MBD3,DDX46,RAB5A,TXNL1,HSPA8,HSPB2 |
| 8.763e-08 | -16.25 | TECR (trans-2,3-enoyl-CoA reductase) | protein interactions | 9524 | 264 | 114 | 19454 | 5460 |
RPN1,CHMP4C,PDHA1,RAF1,B3GNT2,SOX2,TUBA1A,KRAS,VDAC1,BCKDK,ZC3H7A,RB1CC1,PEX3,ATG9A,DYRK1B,MAPK4,MAP3K14,DDRGK1,RAB1B,EGLN3,RAB35,PHB1,VAPB,ELOVL1,SLC25A3,TOMM22,BET1,PGRMC1,EHD1,UFL1,STAU1,YTHDF1,COIL,G3BP2,DDX39B,JAGN1,TMEM106B,HSPA8,HACD1,AKAP1,EP300,LAMTOR1,LMNB1,RHOB,NTRK3,ILK,RIT1,CUL3,RAB11A,BTF3,ACTB,ESR2,MAD2L2,VDAC2,LMBR1L,DLST,RETREG3,FURIN,UBL4A,CCDC47,TP53,AURKAIP1,SLC7A14,TOLLIP,SRPRB,SLC25A10,RAB1A,MAP1B,SLC16A1,ABCE1,STX18,SNRNP70,DPP4,NFKB1,HDAC6,CAND1,FZR1,ARF6,CRB3,CD274,PTPN1,RPA2,STOM,SSR1,GRM2,METTL14,ATG16L1,GABRA1,CFTR,HACD2,CERS2,RPA3,PRKCB,RNF113A,SPOP,CISD1,RC3H2,MFSD14B,ATP1A1,UBE2H,CREB3,PTPN11,FBXO7,DNAJC5,GORASP2,COPE,VIRMA,SEC63,CCNF,UQCRC2,ELOVL4,ALG2,SEC61A1,PTEN |
| 8.800e-08 | -16.25 | TMPRSS2 (transmembrane serine protease 2) | protein interactions | 7113 | 336 | 139 | 19454 | 5460 |
KARS1,TMEM199,CALR,OSBPL8,TMEM11,SLC35A1,ESYT1,PSMD7,SEC23A,SRPRA,ANKRD46,ARL6IP5,CXCL9,COMTD1,CCDC47,TP53,SELENOK,YTHDF2,MRPL11,SLC25A24,GNAI3,TFRC,SFTPC,ADAMTS1,ARPC3,ERG28,ABCE1,IGF1R,STX8,SLC25A11,CLEC7A,SFXN1,ERLEC1,HUWE1,ADIPOQ,HMOX2,TUFM,RACGAP1,GORASP2,CTSD,SLC25A1,VAMP5,XPOT,CALU,ATP1B3,GANAB,SEC61A1,CYBC1,PELP1,PLP1,GNAI2,DEK,TMOD3,PLP2,NTPCR,EDDM3B,SEC22B,MET,CHPF2,CDK1,RPA2,HSP90B1,CLK1,EGFL7,DLAT,TMEM243,RPA3,ITM2B,BANF1,HSPA5,AIF1L,DDRGK1,CLPX,STOML2,C2CD2L,CDK5RAP3,XPO5,STX5,SPINT2,DNM2,PTK7,MPDU1,LANCL1,COCH,RAB1B,HNRNPL,ACTN4,ERLIN2,STBD1,NEU1,PGAP2,PLD3,HGS,RPN1,MYO1B,BAG2,NDUFA4,RAB18,TMEM60,TNF,ETFA,VDAC1,GGH,FMC1,VEZT,CUL2,PLN,SERPINH1,FAXDC2,DCAF4,CGRRF1,MYO6,TMEM229B,VDAC2,GNG12,B4GAT1,ATP6AP2,GNB1,GPC4,SEC22A,EDEM3,RAB6A,CTXN3,TOMM22,EFHD1,PGRMC1,CMTM7,FAM3C,HADHA,DDX39B,ATPAF2,TMEM106B,ZDHHC17,SAP18,ITGAV,STX7,EMC1,UFL1,FXR2 |
| 8.844e-08 | -16.24 | protein-folding chaperone binding | molecular function | GO:0051087 | 133 | 69 | 18094 | 5411 |
CDKN1B,PTGES3,SLC12A2,GPR37,METTL21A,HSPB6,USP13,GRPEL1,PFDN6,DNAJB9,GRPEL2,FGF1,DNAJB2,PPID,HIKESHI,DNAJC1,BIRC5,TFRC,DNLZ,MVD,WRAP53,BAK1,ERP29,BAX,SYVN1,PFDN4,CALR,STUB1,DNAJC3,ATP1A1,BIRC2,AHSA1,CLU,CDK1,SOD1,DNAJC8,CFTR,CDC37L1,DNAJB6,TBCE,UBL4A,TTC4,HSPE1,CTSC,VWF,ST13,HSPA8,HSPD1,BAG3,HSCB,DNAJC2,ALB,SLC25A17,RPS3,TIMM10,NUP62,BAG2,CYP1A1,DNAJB4,PACRG,PLG,PRNP,HSPA5,TERT,DNAJC10,SDF2L1,ATP1A2,ATP1A3,TP53 |
| 8.911e-08 | -16.23 | Hh mutants that don't undergo autocatalytic processing are degraded by ERAD | REACTOME pathways | R-HSA-5362768 | 58 | 38 | 10285 | 3229 |
PSMB3,PSMA6,PSMB6,PSMA2,PSMD1,PSMB2,PSMC5,PSMB11,PSMB10,PSMA5,PSMA4,ERLEC1,PSMD12,PSMC1,PSMC4,PSMB5,PSMA3,OS9,PSMB1,PSMD3,PSMB7,UBB,SYVN1,PSMD4,UBA52,RPS27A,PSMA1,DERL2,PSMD14,PSMC3,PSMD7,PSMB9,SEM1,PSMD6,PSMB4,PSME1,PSMD10,PSME2 |
| 9.003e-08 | -16.22 | TACC1 (transforming acidic coiled-coil containing protein 1) | protein interactions | 6867 | 167 | 79 | 19454 | 5460 |
TOMM20,PXMP2,STX7,RNF41,KDM1A,KRT222,SYVN1,AKAP1,RAB5A,RAB9A,DERL1,FAM50B,EXD2,TMOD1,VAPB,SSR1,FGFR1,RND2,OTULINL,CDC42,SEC62,ST7,TOMM22,ESR2,VIRMA,STAT2,MGST3,RMDN3,SEC61B,TUBA1B,NTRK3,FIS1,MAPRE1,NIF3L1,FBXW11,S100A11,OST4,CUL3,RAB11A,PFDN1,TUSC3,FKBP8,SNRPG,KRAS,RAB3B,POC1B,IGF1R,CYP2C9,TMT1A,STIM1,RPN1,TUBB4B,PTRH2,RAB4A,NHERF1,DNAJC25,MTCH2,LMAN1,TMPO,STX6,COX14,DNAJC1,GJA1,HSD17B11,RAC2,STX5,SOSTDC1,PTPN1,RAB35,ARL10,RB1CC1,BRD3,RHOG,TDRD7,ESYT1,KXD1,RAB5C,MARCHF5,SLC25A46 |
| 9.003e-08 | -16.22 | GDI1 (GDP dissociation inhibitor 1) | protein interactions | 2664 | 143 | 70 | 19454 | 5460 |
RAB5C,RAB32,RAB23,RAB22A,H2BC17,RAB3A,FUBP3,FBXO32,RAB31,RAB35,RAC2,PRNP,RHOH,FAM98A,DCUN1D1,RAB1B,RAB11B,RAB33A,HEXA,SOX2,RAB4A,RAB6B,GDI2,EZH2,RAB1A,MAP1B,RAB13,RAB27A,RAB3B,GNL1,NEDD8,RAB8B,SAR1B,RAB18,RIGI,PSEN1,RAB11A,ALDH1L1,RAB2A,ACO2,HSPA14,DNAJC5,GGH,AR,RUNX1,LGALS8,SPOP,ZNHIT6,MSN,SGTA,TAGLN2,RAB14,GNAI2,VIRMA,ACAP2,TANK,RAB6A,CFTR,CDC42,RPA2,PAK2,SIRT7,SOD1,RPA3,BAP1,RAB5A,RAB9A,RABAC1,UCHL3,GINS3 |
| 9.061e-08 | -16.22 | Srp72 (signal recognition particle 72) | protein interactions | 66661 | 208 | 94 | 19454 | 5460 |
RPS14,RPLP0,RPL26L1,TFB1M,SIRT7,PNO1,UTP23,RPL4,RPS15,RPS17,RPL7A,ZNF687,IGF2BP1,RPS12,SRP54,POP7,RPS3,BCCIP,RPL22,RPL13A,RPP25L,ZNF622,RPL15,H2AX,CHAMP1,HSD17B10,RPL3,RPL23A,NKRF,RPL17,MEPCE,RPS13,NOC4L,IMP4,PAK1IP1,MPG,SPATS2L,ATP5MG,ERCC3,RPL10A,RPS2,RPL24,RPL32,MRPS9,EIF2B2,SEMA3C,RPS16,RPL27A,TRMT112,CCDC86,HADHA,RFC4,CMAS,STAU1,TSR3,RPS29,RFC5,NOP16,RPS5,FTSJ3,H1-10,RPS9,FAU,RPL19,RPL10,RPL7L1,RPS7,TPD52,TRMT1L,RPS23,RPL18,RPS11,RPS24,HNRNPA2B1,RPL31,TRIP4,RFC3,RFC2,RPS4X,RPL28,RPL6,RIOX2,HMGA1,BAZ1B,RPL23,HP1BP3,EED,RPL8,HMG20A,RPL7,LYAR,NOP58,MEAF6,RPS10 |
| 9.135e-08 | -16.21 | cellular response to endogenous stimulus | biological process | GO:0071495 | 1135 | 414 | 18204 | 5365 |
P2RY4,ELAVL4,VSTM2A,ITGB5,WNT7A,FAM107A,AIFM1,TBC1D4,AKT1,NDNF,TGFB3,TLR6,DRD3,SMAD4,GRB10,SELENOS,IGF1,EP300,UCP2,PIK3R3,NSG1,CALR,GH1,CTNNB1,SLC1A1,AGTRAP,NPR2,MAP1B,HYAL2,SLC1A2,CTSK,MT3,GPT,OXTR,XBP1,GRIA1,PID1,FLRT3,PAK2,MIR130A,TGFBR2,SLC8A1,TRIM24,AR,NCOA5,CRKL,BCL2L1,JAK2,FGF1,NR1H2,STAT1,PCSK9,NRP1,RAMP3,PRKCE,EGLN2,GSK3A,RGMA,UGCG,ACACA,AKT2,PRL,JUN,CA2,ERRFI1,EEF1A1,PPARA,RXRG,VEGFC,SLC1A3,SLC2A8,YWHAG,TMEM100,ACVR1C,UBE3A,RNF14,EIF4E,AHCYL1,CSK,NDST1,BGLAP,MIR107,GNAQ,ADIPOR2,PADI2,GNAO1,PLCB1,TLR9,PCK2,TNFRSF1B,RWDD1,GNRHR2,SMURF1,JAK1,MSX2,SELENON,EHD4,FGFBP1,MIR30B,MIR21,SMYD3,SIN3A,PAX6,SERPINB9,WNT10B,DSTYK,EDNRA,CD36,CIB2,NUS1,ARPC3,LDOC1,FGF16,GNB1,ACVR1B,RAB14,NKX3-1,FCGR2B,NOG,HDAC6,ADIPOR1,STC1,LHB,SMAD3,DUSP22,WNT2,HNRNPD,COL1A2,UBE2L3,CRHBP,TMEM108,RAP1A,EIF4A3,YES1,CD2AP,RARRES2,MIR183,NDP,CYP1B1,FKBP4,RAB35,P2RY11,FRS3,VPS54,STAT5A,FEZ1,NPPC,BMPR1B,NHERF1,FOS,CCL2,PML,SOSTDC1,WBP2,PDE2A,NFKB1,DRD1,GNA11,EXT1,PTGES3,MGARP,SST,CSH1,SRC,CALY,GNG2,TFPI,PHB2,BACE1,MIR140,PIK3CG,INSIG2,LEP,PIK3CA,ICAM1,NTF4,STK16,PDCD4,P2RY12,CAMP,MIR143,ACAP2,NR2E1,PIK3R1,RAN,PIK3R2,AMIGO1,NTRK3,FLRT2,STMN2,NTRK2,SHOC2,MIR493,RXFP2,ABHD2,SMAD9,AKR1C2,NFE2L2,AKR1C1,BMPR1A,FGF23,MECP2,BMPR2,VEGFA,LPXN,GCLC,SPINT2,PTPN22,PDE8A,COL3A1,GSTM2,DDIT4,STAT6,FOLR2,CST11,ADTRP,SULT1A3,ADRB2,NOTCH2,ACTA2,TGFB2,MAP2K3,DUSP3,FGF10,SESN3,GJB2,GABRG2,AANAT,GHRL,MIR20A,CPEB1,TADA3,CTNNA1,SOX9,CBL,BECN1,SNAI2,FMOD,RAB13,ATP1A2,CHST11,RGMB,OR51E2,SMAD1,EIF4EBP2,MIR339,KDM1A,CTSB,GAD2,CAV2,HDAC5,SHC1,GNA14,RAP1B,CRHR1,PDCD5,YWHAH,ID1,ATP5F1A,HTR2A,REN,INPP5K,KLF9,SMAD5,USP15,OPRM1,MIR106B,CCL5,SOS2,MIR200A,EPHA4,DEFB124,DLX1,PELP1,PTGER2,FERMT2,FBXO32,CSNK1E,IGF1R,CREB1,SFRP1,FLCN,HSPB1,SOCS2,MARS1,MIR142,GABRB2,HTRA2,ZMPSTE24,SMAD2,BRCA1,ATP1A3,MIR149,CLDN1,IDE,DTYMK,GPR22,PSEN1,MIR146A,CAV1,RBFOX2,TAB1,HTR1A,USP8,FURIN,ZYX,MEF2C,STAMBPL1,EFNA5,MSTN,CAV3,TOP2B,FGF7,GABRB3,HFE,CDK5,MIR98,CXCR4,ITGB8,FBP1,AGER,HRAS,MIR23A,CHRDL1,FGF3,TWSG1,CYP11B2,ACTB,ADIPOQ,TNF,SHMT1,FGF17,MIR1298,RAF1,XCL1,IL10,PTGFR,AVPR1B,ATP1A1,MSX1,PAQR8,MIR145,CX3CR1,PHB1,PPP1R1B,GJA1,CFTR,CASTOR2,ACVR1,ARF6,FOXC2,FUT8,CSNK2B,FOLR1,VAMP2,HSP90B1,NDN,EID2,CASP4,PTGER1,RAB31,SLC22A12,CYP11B1,CITED1,RB1,FGFR1,P2RY1,TSHR,UGT1A1,TMEM38B,TRIP4,COMT,PTPN1,FGF22,GHR,HSPA8,KLF4,PTPN11,PAX9,TLR4,CXCL8,MDM2,TAF7,TAC1,GNAI3,TP53,FKBP8,HPCA,SOST,GPR173,LEPR,DDX5,EHD1,GAB1,KLHL22,JUP,SESN2,PGR,CHMP5,CXCL13,SP1,PPARG,MIR212,CCNA2,PTGER4,RPL23,MIR30A,NR4A2,SLC6A4,EGR1,MKKS,ESR2,NCSTN,EZH2 |
| 9.150e-08 | -16.21 | RAB14 (RAB14, member RAS oncogene family) | protein interactions | 51552 | 197 | 90 | 19454 | 5460 |
STX7,NRBF2,EMC1,ADRB2,GPM6A,PMAIP1,AKAP1,PIH1D1,KCTD12,DUSP22,ATP6V1C1,ACTL6A,ATP6AP2,MB21D2,LAMTOR3,LMBR1L,FIS1,OSGEP,LAMTOR1,TOMM40,MYC,KRAS,HNRNPF,VDAC1,ENPP4,CCR1,STX12,MOB3C,EZH2,RAB4A,GDI2,DSTYK,HSDL2,FEN1,RAF1,RAB1B,OCRL,AASDHPPT,EED,RAB35,DUSP6,HAX1,AGR2,PRPF19,LAMP2,IFI16,RAB5C,HSPA5,ABCC2,FLCN,RTN4,BAP1,RPA3,HEXIM1,RPA2,STX17,FGFR1,WWP1,CDC42,CFTR,TIMMDC1,VIRMA,GARIN6,TXN,THAP8,VAMP3,CCNF,OPTN,SCAMP2,NRP1,SH3BP5L,LGALS8,EXOC5,RAB2A,SEC13,OLA1,RAB1A,TFRC,MAP1LC3B,RRM1,UBL4A,ILVBL,ARF6,DERL2,COMT,AGPAT1,CD81,LAMP3,EMC4,LAMTOR2 |
| 9.440e-08 | -16.18 | MRPS2 (mitochondrial ribosomal protein S2) | protein interactions | 51116 | 270 | 116 | 19454 | 5460 |
MRPS25,NOA1,MCAT,AUH,MYC,MTG2,PMPCA,CUL3,DYNLL1,ESR2,RPL10,TACO1,CCDC90B,MTG1,RPS9,KLC2,TIMM29,HSCB,UFL1,NOP53,RANBP10,MRPS7,NGRN,EXD2,RHOG,MRPS26,ARMC8,MTRF1,RPL6,MRPS35,ATG7,HNRNPA1,DDRGK1,TRA2A,RMND1,HDHD5,GATD3,PDHA1,RPS23,RAF1,TPD52,LYPLA1,SOX2,KRAS,KGD4,MRPS17,IMMP2L,HSPD1,MKLN1,HINT2,HSD17B8,ZC3H7A,MRPS11,COX8A,SRSF7,MRPS16,RC3H2,YPEL5,DNAJC19,UBE2H,RPL26,TUFM,MRPS21,MRPS28,LMNA,RPA2,MRPS34,FGFR1,HEXIM1,ZNF574,MTRES1,KLF4,COQ8B,CRAT,RBMS2,CDK7,KLF12,SLC25A51,CRYZ,RPA3,GID4,GID8,GFM1,TMEM70,CHCHD1,SNRNP70,GRSF1,NR2F6,E4F1,CAND1,FZR1,CGAS,RBM42,SLC25A12,MRPS23,MRPS9,SSBP1,COX4I1,MGME1,ACTA2,ALYREF,TRMT10B,PRR3,GFM2,TP53,MRPL11,AURKAIP1,APOBEC3D,METTL15,MRPS33,MRPS18C,MEPCE,FASTKD5,MRPS18B,HAPSTR1,CLPB |
| 9.471e-08 | -16.17 | Stabilization of p53 | REACTOME pathways | R-HSA-69541 | 56 | 37 | 10285 | 3229 |
PSMB3,PSMA6,PSMD1,PSMB2,PSMA2,PSMB6,PSMB11,PSMC5,PSMB10,PSMA5,PSMA4,PSMD12,PSMC4,PSMC1,COP1,PSMB5,PSMA3,MDM2,PSMB1,PSMD3,PSMB7,PSMD4,UBB,UBA52,RPS27A,PSMA1,PSMC3,PSMD14,TP53,PSMD7,PSMB9,SEM1,PSMD6,PSME1,PSMB4,PSME2,PSMD10 |
| 9.471e-08 | -16.17 | SCF-beta-TrCP mediated degradation of Emi1 | REACTOME pathways | R-HSA-174113 | 56 | 37 | 10285 | 3229 |
PSMA1,PSMC3,PSMD14,PSMD4,UBB,RPS27A,UBA52,PSME1,PSMB4,PSMD6,SKP1,PSMD10,PSME2,PSMD7,SEM1,FZR1,PSMB9,PSMB10,PSMA5,PSMB11,PSMC5,PSMA4,PSMA6,PSMB3,PSMB2,PSMD1,PSMA2,PSMB6,PSMB1,CDC20,PSMB7,PSMD3,PSMC4,PSMC1,PSMD12,PSMB5,PSMA3 |
| 9.471e-08 | -16.17 | Degradation of AXIN | REACTOME pathways | R-HSA-4641257 | 56 | 37 | 10285 | 3229 |
PSMA4,PSMB11,PSMC5,PSMB10,PSMA5,PSMB2,PSMD1,PSMA2,PSMB6,TNKS,PSMB3,PSMA6,PSMD3,PSMB7,PSMB1,PSMA3,PSMB5,PSMD12,PSMC4,PSMC1,PSMC3,PSMD14,PSMA1,UBA52,RPS27A,RNF146,PSMD4,UBB,PSMD10,PSME2,PSMD6,PSME1,PSMB4,PSMB9,SEM1,PSMD7,TNKS2 |
| 9.518e-08 | -16.17 | CAV2 (caveolin 2) | protein interactions | 858 | 112 | 58 | 19454 | 5460 |
ATP5MK,ATP5IF1,TACR1,ATP5F1E,RER1,PHB2,STK38,ATG16L1,SDCBP,ATP5PO,CAV2,VDAC2,S1PR4,EDNRA,REEP4,ATP5F1B,SRC,PSMB6,ATP5F1A,RHOB,IVNS1ABP,KCNMA1,ATP5PF,SFXN1,TMEM147,PRPSAP1,VDAC1,ATP5F1D,TMEM33,TRIM37,AKAP12,PRPS1,PDE2A,RAP1A,STBD1,ATP5PB,DRD1,YIPF3,RPN1,SURF4,NUPR1,CYB5B,PHB1,STT3A,HACD3,HRAS,RAB35,RAP1B,RAB1B,CAV1,ATP5PD,ATP5MG,HM13,CSNK2A1,NCK1,POR,RHOG,HSPB1 |
| 9.518e-08 | -16.17 | TTLL12 (tubulin tyrosine ligase like 12) | protein interactions | 23170 | 112 | 58 | 19454 | 5460 |
NDN,TUBB,UBE2V2,VIRMA,TNPO3,OPTN,SRXN1,LMBR1L,STUB1,XPOT,DNAJB6,AR,GGH,STAU1,RPA3,BAP1,SIRT7,FAM222B,NUP50,DR1,TTC1,VPS4B,RPA2,PSMB7,RPRD1B,FKBP10,RPL35A,CPNE1,TTC9C,SUMO2,EGLN3,CAV1,WIF1,SIN3A,RPRD1A,EEF1AKMT3,FBXO32,PBDC1,SEC23A,UBE2D1,YWHAG,UFM1,RBCK1,UBE2A,SOCS2,AHCYL1,ZYX,PPP1R12A,DNAJB4,ACTR2,UBE2B,ZRANB2,PPME1,CCR1,RAF1,TP53,MAP1LC3B,EEF1A1 |
| 9.528e-08 | -16.17 | Cytoplasmic Ribosomal Proteins | WikiPathways | WP477 | 90 | 57 | 5310 | 1910 |
RPL8,RPL10A,RPL27A,RPS13,RPS26,RPL23A,RPS2,RPS29,RPLP0,RPL35,RPL7A,RPL24,RPLP1,RPS28,RPL23,RPL31,FAU,RPL7,UBA52,RPL6,RPL4,RPS17,RPS27A,RPS9,RPL19,RPS3,RPL10,RPL35A,RPL12,RPL15,RPL29,RPS24,RPS15,RPL32,RPL17,RPL9,RPL26,RPL28,RPS10,RPL22,RPS14,RPS4X,RPS12,RPS20,RPS23,RPL27,RPS11,RPS16,RPS5,RPLP2,RPL18,RPS7,RPSA,RPL39,RPL13A,RPL3,RPL37A |
| 9.655e-08 | -16.15 | PDIA6 (protein disulfide isomerase family A member 6) | protein interactions | 10130 | 293 | 124 | 19454 | 5460 |
CDC73,UBE2H,CALU,LGALS8,RC3H2,TXNIP,DNAJC10,FBXO7,CIAO1,SMURF1,VIRMA,GTF2A1,TRIM24,CCNF,CTTN,HEXIM1,UBE2M,RPA2,P3H1,HSP90B1,METTL14,CFTR,ATG16L1,JMJD8,PIAS1,HSPA5,DPEP3,RPA3,SOD1,BAP1,UGDH,TNFRSF14,NME2,CRBN,HDAC6,CSNK2A1,COPS5,CD81,DPP4,CALR,CXCL12,ADIPOR2,PLEKHO1,FAM20C,CAND1,KCTD15,FZR1,CLN8,HSPA13,DDX42,ACOT13,H2AX,UBR7,RPSA,MEPCE,GNMT,HUWE1,DNAJC30,POC1B,HSD17B10,FAF1,KLHL24,NTRK3,COP1,SERPINH1,DCAF4,PDE4B,MYC,CUL3,MAT2B,PSMD4,TENT5C,PRMT5,SMU1,SEC61B,TACO1,ZHX3,LMBR1L,DLST,PIH1D1,DET1,NEK7,NOTCH2,UBL3,PAFAH1B1,FBXL4,UFL1,ADRB2,ATP5IF1,TXNL1,HDAC5,PMAIP1,EP300,TTC1,PSMA3,DNAJC3,TMEM106B,MED4,PPP3CA,AGR2,DDRGK1,IFI16,PDIA3,PFDN5,DNAJB9,CCAR2,KCTD10,IGBP1,XPO5,PHB1,PLD3,SART3,EZH2,RPN1,NGB,CHMP4C,RAF1,TPD52,B3GNT2,CSNK1E,TXNRD1,RBBP7,EWSR1,UBE3A |
| 9.675e-08 | -16.15 | negative regulation of transmembrane transport | biological process | GO:0034763 | 145 | 73 | 18204 | 5365 |
MIR212,PPIF,ARL6IP5,MIR153-1,ATP1A2,PLN,TLR9,MIR208A,PID1,GSTO1,MIR129-1,PRKCB,PRKCE,GSK3A,FKBP1B,SRI,CRHR1,CAV3,MIR448,GPR35,SUMO1,EPO,CTTNBP2NL,FKBP1A,CLIC2,KCNAB1,CAV1,MIR200C,PPP3R2,FABP5,PCSK9,MIR208B,OAZ2,CRBN,CAB39,HECW1,OXSR1,DRD3,LEP,SELENOS,GRB10,PPP3CA,MIR30D,AKT2,MIR495,MIR186,VDAC1,TMBIM6,RGS2,IL1B,INPP5K,GSTM2,AKT1,OAZ3,TCAF2,MIR1-1,SESTD1,MIR143,OAZ1,MIR9-1,MIR107,MMP9,MIR34A,MIR873,TNF,PEA15,SLC43A2,MIR34B,MIR133B,MIR192,ISCU,MIR24-1,MIR185 |
| 9.814e-08 | -16.14 | RCN1 (reticulocalbin 1) | protein interactions | 5954 | 239 | 105 | 19454 | 5460 |
RNF41,AKAP1,EP300,SPECC1L,TMEM106B,LCA5,ATPAF2,DNAJC3,SLC25A3,MYL6,MAP2K1,LMO3,TOM1L2,LMO4,YIPF5,ASB8,BET1,JAK2,GADD45G,LGALS3,MTM1,MATR3,SEC61B,ENO2,EFHD2,SRXN1,HTRA2,ILK,HMGCS1,BTF3,GFUS,CUL3,MYC,LMO2,IMMP2L,SAR1B,ENKD1,CCAR1,UFM1,ZYX,GNB1L,CHMP4C,HDAC11,TUBB4B,ASPM,PPIL3,B3GNT2,TOP3B,PCSK9,DNAJB9,CETN3,HP1BP3,DCAF11,HSPA5,METTL22,FBXW7,RAB9A,EGFL7,BAP1,CYC1,HAUS2,MET,PTPN22,HSP90B1,CFTR,VIRMA,ARMC6,RPGRIP1L,COPE,CTSB,MACROH2A1,PTEN,MSN,SGTA,TUBA1B,ENO1,CCNF,CALU,UBE2H,NRP1,DNAJC10,GMPS,SMARCA5,PTGES3,DUSP19,DUSP21,DNAJC30,HSPE1,HSD17B10,IGF1R,IDH1,EFHC1,FURIN,ILF2,TFRC,TES,SEC23A,RCHY1,SSX2IP,KPNA1,COPS5,FAM20C,CALR,DPP4,MOV10 |
| 9.842e-08 | -16.13 | SPR (sepiapterin reductase) | protein interactions | 6697 | 107 | 56 | 19454 | 5460 |
COX4I1,DSTN,GATD3,MIF,SUMO2,NUP35,PSMD3,PRDX1,ELOC,SMAD4,HINT2,IGF1R,HINT1,UFM1,CAMK2G,SRPRB,HSPE1,AHCYL1,MPST,CMPK1,NDUFA2,GLRX5,HADH,RAD23B,MRPL53,LDHA,TAGLN2,PRDX2,LGALS3,YES1,SRC,CLIC4,MYC,SUGP1,ACO2,PMPCA,MTPN,MDH1,FXN,SERPINH1,PEBP1,RPA3,PTRHD1,PPM1G,SOD1,COX17,HSPA8,PRDX6,YKT6,LYPLA2,POLDIP2,CRYZ,LAP3,RPA2,GSTP1,PIH1D1 |
| 9.868e-08 | -16.13 | MRPS28 (mitochondrial ribosomal protein S28) | protein interactions | 28957 | 225 | 100 | 19454 | 5460 |
PTEN,MRPL53,TUFM,USP14,DNAJC19,UBE2H,IGF2BP1,YPEL5,SQSTM1,GFM1,BAP1,UTP23,CRYZ,ABCC2,MRPL41,RBMS2,KLF12,KLF4,MTRES1,HEXIM1,GRM2,MRPS34,TRMT10B,PRR3,COX4I1,ALYREF,SSBP1,MRPS9,AIFM1,SYNCRIP,ZBTB2,MRPS23,CGAS,CAND1,FZR1,GRSF1,TMEM70,SNRNP70,CHCHD1,MRPS18B,PQBP1,SLC25A10,SNRPG,MEPCE,MRPS18C,FASTKD5,SRPRB,METTL15,AURKAIP1,TP53,MRPL11,ILF2,GFM2,MRPL13,RPS9,CCDC90B,MTG1,TACO1,PRRC2A,DYNLL1,CUL3,PMPCA,CFAP20,NDUFB6,MTG2,MYC,AUH,MCAT,MRPS25,RBM27,YWHAZ,FBXW11,LAMTOR1,RPS28,EXD2,NGRN,HSCB,UFL1,MRPL12,GATD3,RMND1,HNRNPL,DDRGK1,YWHAH,HNRNPA1,MRPS35,MTRF1,MRPS26,RHOG,MRPS11,SRSF7,COX8A,HINT2,RBM3,HSPD1,MRPS17,FGD2,SOX2,RAF1,PDHA1 |
| 9.879e-08 | -16.13 | regulation of epithelial cell proliferation | biological process | GO:0050678 | 415 | 172 | 18204 | 5365 |
TMIGD1,FGF16,MIR495,MIR205,FGF7,HMGB1,SAV1,CXCL12,NOG,EAF2,HDAC6,FBXW7,NKX3-1,MIR98,NME2,DUSP10,STK11,HRAS,MIR23A,ZNF304,MIR361,TNF,CCR3,IL10,RBPJ,MIR24-1,MIR101-1,SMAD3,DBH,WNT2,RAB33B,LACRT,FA2H,EGFL7,PRKCA,MIR222,AGGF1,CDK4,STAT5A,CCL2,MIR16-1,RB1,MIR424,NME1,FGFR1,VASH1,TNFSF12,ANGPT1,CCL11,PHB2,APLNR,LEP,KRIT1,CDK6,IFT52,MIR133B,STK4,SYNJ2BP,MIR15A,MIR135B,MIR34A,MIR193A,CDKN1B,MIR30E,PGR,PPARG,MIR503,JAML,SP1,MIR181C,BMPR1A,VEGFA,B2M,MIR29A,SOX2,WNT7A,AKT1,MIR152,CDH13,SEMA5A,PROX1,PDCD10,HMX2,IGF1,NOTCH2,OVOL1,TGFB2,WDR77,VDR,CTNNB1,FGF10,TNFAIP3,IRF6,GPX1,CCL24,ODAM,GHRL,RGN,PROK1,XBP1,SOX9,MIR130A,ATP5IF1,MIRLET7B,SNAI2,CCND1,DLG1,MIR492,MIR497,TRIM24,AR,MIR29C,LIMS2,MIR200C,NRP1,CAV2,FGF1,B4GALT1,STAT1,MIR10B,BAD,ATP5F1A,PRL,APLN,KLF9,OSR2,FUT1,AKT3,MIR132,SCG2,IL12A,MIR10A,MTA3,VEGFC,STK3,EMC10,CCL5,CASK,POLD4,IL12B,SFRP1,FLCN,MIR126,MYC,BAX,IFT172,NUPR1,CDC42,RTN4,FMC1,RGCC,TACR1,IFT57,MIR342,AQP11,SLC39A9,SFN,CLDN1,MIR149,MIR146A,MIR21,MIR30B,FGFBP1,CDC73,PTN,PAX6,CAV1,WNT10B,GPBAR1,MIR129-1,MEF2C,MIR150 |
| 9.925e-08 | -16.13 | ORF50 (ORF50) | protein interactions | 4961526 | 92 | 50 | 19454 | 5460 |
MAT2A,ZSCAN25,FYTTD1,CHTOP,MCAT,ZNF177,UBE2I,ERH,ACAP2,SUMO1,ATP6V1E2,ZCCHC17,ZNF326,HECTD1,RPL27,TCEA1,DDX5,LCP1,SRSF2,PHB2,HSPA5,SPATS2L,HM13,UBE2D1,MRPS26,HNRNPD,SRP14,RPL9,RPS16,EIF2S1,LYAR,SNRPA1,SUMO3,SUMO2,MDM2,CCT7,HSP90AB1,CWC15,PPP2R1A,FAF2,CTSA,RBPJ,ILF2,SNRPE,PABPC1,PCNA,SRSF7,TRIM26,HNRNPK,RUVBL1 |
| 1.002e-07 | -16.12 | VAPB (VAMP associated protein B and C) | protein interactions | 9217 | 449 | 177 | 19454 | 5460 |
GPAA1,TMT1A,SACM1L,G3BP1,FAF2,RAF1,RPN1,VAMP2,STIM1,NME1,NGB,NDUFS6,GJA1,PHB1,ERLIN1,WIF1,WDR44,STK3,SNX2,FAM174A,MARCHF5,MAP1S,PTPN5,RB1CC1,STX1A,RHOG,TTC1,DUSP9,STX7,COIL,PXMP2,RND2,OTULINL,PGRMC1,VAPB,RMDN3,SEC61B,PIGK,GNB1,MAD2L2,REEP4,SYNE4,RAB11A,SCN3B,NTRK3,SCFD1,YWHAZ,CYB561,LMNB1,GNG5,IGF1R,NTRK2,PTGES,NSDHL,LTBR,FAF1,RIGI,LBR,CCDC47,COMTD1,TMEM101,HSD17B11,PTPN1,ATP5PD,FAM118B,AIG1,ARF6,LAMP3,SLC25A46,STYK1,OSBPL8,ESYT1,SYVN1,RTN4,KLHL28,SQSTM1,SLC39A9,RPA3,FAXC,ST7,SYNRG,TIMMDC1,SEC22B,COX6C,LMNA,STOM,TUBA1B,ELOVL4,TECR,SEC63,COPE,CYP2C9,KRAS,TUBA1A,DNAJC25,SOX2,NDUFA12,RAB4A,PTRH2,STX5,RAB35,COX14,AFTPH,RHOH,OSBP,YWHAG,YWHAH,STK4,LAMP2,RAB5C,YWHAB,NDUFB8,DEGS1,AGR2,HSPA8,RAB5A,JAGN1,OXCT1,SEC62,VAMP1,TOMM22,BET1,PPT1,RETREG3,LMBR1L,CBX5,ESR2,RNASEK,SLC1A3,OST4,HNRNPC,FIS1,ZMPSTE24,SPCS3,ABCE1,CYBRD1,MPST,FKBP8,RHBDD3,KPNA2,RAB3B,ATP5PB,UBL4A,TP53,MTCH2,SLC25A24,TFRC,RAC2,COX4I1,TMPO,SELENOI,LMAN1,SURF6,FZR1,DNAJC1,CAND1,DHRS7,MTMR12,ZDHHC15,AQP2,BCL10,RAB9A,DERL1,TMX2,TOMM20,CDC42,CFTR,RPA2,FGFR1,SSR1,SLC1A1,UQCRC2,PRKACB,MORF4L1,KCNB1,SNX5,BICD2 |
| 1.004e-07 | -16.11 | LAP3 (leucine aminopeptidase 3) | protein interactions | 51056 | 102 | 54 | 19454 | 5460 |
PRDX1,COX5A,ARMC8,COX4I1,GATD3,TES,SPPL3,MIF,UBL5,TP53,HADH,GLRX5,ISG15,EZH2,CBX3,SH3GLB1,ZYX,GUK1,MPST,SAR1B,MYC,PMPCA,PIK3R3,MTPN,RHEB,SPOP,NIF3L1,DCAF4,FXN,UBE2H,MDH1,ACOX1,UQCRC2,CTSB,PRDX2,TENT5C,PRKCE,TAB1,CBX5,ESR2,CLIC4,SPR,IDH2,ZCCHC17,GSTP1,UBE2M,RPA3,BAP1,UGDH,HSPA8,PRDX6,ARPC2,UFL1,CRYZ |
| 1.004e-07 | -16.11 | SKP1 (S-phase kinase associated protein 1) | protein interactions | 6500 | 458 | 180 | 19454 | 5460 |
CDKN1B,KDM2A,UBE2D1,NDC80,MARCHF5,CACYBP,EGLN3,MPP1,SNX18,COPS7B,FBXO32,PSMB5,PSMB4,PHB1,RBPJ,FBXL3,CHMP4C,CKS1B,RAF1,AHCYL1,PCGF6,COPS4,PCGF3,ARB2A,RIT1,HSP90AA1,PFDN2,DCAF4,BRCA1,FAS,CUL2,CUL3,ACTB,DYNLL1,WNT10B,PSMB7,CDKN1A,FBXO30,SKP1,FBXL4,PSMA3,CRY1,FBXW4,BRD3,FBXO34,MED21,CRBN,NME2,NFKB1,CDK9,PSMB1,CDCA3,SSU72,ETV6,SMAD3,PDE6D,FBXO8,UBE2B,TBK1,PSEN1,FBXO25,BACH1,RING1,FAF1,DEDD,CCDC22,PIP4K2C,PPP1CC,FBXO7,CDC16,VIRMA,PTEN,GSK3A,CCNF,CCNA2,CCND1,MBD3,FBXO9,FBXW7,YWHAB,CDC23,DRG2,IKBKB,CTNNB1,YWHAG,TTC9C,HNRNPL,EED,CORO1C,FBXO31,MOB3C,KLHL12,BTG1,GHR,CBLN4,FBXL7,MAX,MAGEC2,FKBP2,FOXN2,RUVBL1,KRAS,PSMA1,PSMA2,TRIM21,FBXO11,RUVBL2,FBXO3,POLR1B,COP1,FBXW11,BAG3,BTF3,PSMA4,SFN,MYC,LMO2,MORC4,PSMB6,FBXO22,ANAPC2,NFKBIB,NFKBIA,FBXL14,PIH1D1,CTBP1,PAK2,PSMB3,FBXO42,PTAR1,STAU1,PCGF2,YAF2,HSPA8,USP15,H2AC4,SNRNP70,TUBG1,GAPDH,COPS5,CSNK2A1,MBD5,FZR1,CAND1,MCL1,PHC1,NUPR1,CDK4,TP53,MEPCE,KPNA2,PSMA5,NEDD8,BHLHE40,UBE2H,ANAPC4,KCNMA1,FBXO44,GJB2,CCNB1,RNASET2,PSMB2,TRAF1,KCTD9,TRAF7,CSNK2B,PSMA6,KLF4,HECTD1,GIT2,UBE2M,HEXIM1,BTG2,RPA2,CFTR,FBXL19,RNF113A,PML,ARHGEF6,BAP1 |
| 1.012e-07 | -16.11 | FLII (FLII actin remodeling protein) | protein interactions | 2314 | 276 | 118 | 19454 | 5460 |
RTCB,RUVBL2,AHCYL1,NAT9,RFC2,TRIM37,RUVBL1,KRAS,TNF,RBBP7,TULP3,TNPO2,ISG15,SOX2,OTUD6B,CRYGD,TOP3B,RAF1,RBPJ,SMARCB1,POLR2C,MTA2,EIF1AX,VPS33A,EGLN3,DYNC1I2,TTC9C,CTNNB1,TRIM8,PRKX,IFI16,DCAF11,MED4,HAX1,DDX1,EP300,AKAP1,HSPA8,RFC4,DDX39B,FTL,FBXO30,STAU1,PPP1CB,ACTL6A,CSNK1A1,ANAPC2,PRMT5,DLST,APEX1,ESR2,PPP5C,ACTB,RBBP4,FBXO22,MATR3,BTF3,CUL3,MYC,HSP90AA1,FBXW11,BRCA1,LAMTOR1,DHX9,PPP1R12A,MYD88,MSH6,PTGES3,PSMB10,FBXO25,KPNA2,ACTR1A,FBP1,NUPR1,DISC1,CAPZA2,MYL12A,CDK9,HDAC6,CALR,USP15,TUBG1,SMG5,RPL27,BAP1,RPA3,HSPA5,CRYL1,SMC4,FBXW7,DGCR8,KDM1A,CFTR,CCND1,ATG16L1,TMOD1,EIF2B3,RPA2,CTU1,RTRAF,TUBA1B,EIF4A3,OPTN,CCNF,VIRMA,SH3BGRL,ADRM1,TMOD3,DAPK1,AR,PPP1CC,SUB1,SMARCA5,AKT1,HERC4,PAIP2,CCDC174,SPOP |
| 1.024e-07 | -16.09 | Golgi membrane | cellular component | GO:0000139 | 683 | 261 | 19108 | 5553 |
MGAT5B,ZDHHC4,ROCK1,GOLGA7B,INPP5E,STX10,ARFGAP3,DIPK2A,CREB3,TAPBPL,NAA60,FKTN,CHST13,STX5,AP1G2,SACM1L,SURF4,ATP6V1D,FURIN,RAB6A,MGAT1,MARCHF4,RNASEK,TMED7,GALNT2,AP1M1,RER1,SLC35B4,NDFIP1,RHOU,FAM20B,GNAI3,B3GALT4,PXYLP1,CD1E,SCFD1,TMEM115,GORASP2,PARM1,CYTH2,SLC35B3,LST1,SLC30A5,YKT6,GNPTG,SLC35A2,RRAS2,PGAP4,CD59,RAB6B,NOTCH2,KRAS,RAB11A,GABARAP,FUT8,APOO,FOLR1,CYTH1,MARCHF9,SYT4,RND3,ST8SIA5,C1GALT1C1,CHST11,TLR9,TLCD3B,PSEN2,MOSPD1,HAS3,CHPF2,STX12,CNIH1,UNC50,ARFGAP1,SCAMP5,APH1A,ARF1,SLC35A5,PDCD10,GNPNAT1,GAD2,TNKS2,FUT1,EXT1,SLC35A1,UST,B3GALT1,TVP23B,ATG9A,TPST1,GJA1,ZDHHC15,SYS1,ATP6AP2,GASK1B,SERINC3,OPTN,ARFGEF1,SNAPIN,B4GALT4,CHST2,GLIPR2,ST3GAL4,RAB9A,TMEM87A,NDST1,SGMS2,TLR7,MAN1A2,HRAS,UBIAD1,TMEM165,TRAF3IP3,TLR3,PGAP2,B4GALT6,B4GALT3,DNM2,SEC23A,WSCD1,SLC39A13,CYTH4,B4GALT7,COG1,OSBP,TNKS,GOLGA7,COPZ2,RAB1B,PAQR3,GPR89A,PLD3,GOSR1,GOLPH3L,SGMS1,HYAL2,ENTPD4,RHEB,NLRP3,NCSTN,CLSTN3,B4GALT1,TEX261,ARHGAP21,STX6,RAB2A,RAB33B,TMEM59L,EMP2,IL15RA,BET1L,SLC30A7,HUWE1,ARCN1,ATL1,PGAP3,HS2ST1,LYSET,RAB30,ST3GAL1,TRIM23,SYBU,ATP6V0B,GOSR2,B4GAT1,GALNT12,NDST3,ST6GALNAC3,CDC42,AGTRAP,ATP2C1,CAV1,SNAP29,CSGALNACT1,ST3GAL2,GCNT3,CAV3,TMED3,GALNT4,GABARAPL2,SLC35C1,FKRP,RAB14,LITAF,PSEN1,TAPBP,BET1,GCC1,YIF1A,MGAT4A,STX18,FUT9,TMED9,GALNT1,TRAPPC3,B3GALT2,CREB3L4,MGAT4B,CSGALNACT2,GALNT17,PSENEN,TLR8,KDELR2,LMAN1,ARF4,ZDHHC8,CAV2,VAC14,KPNA2,TMEM50B,TRAPPC4,CHST7,RAB1A,ARFIP1,ICA1,GOLGA5,ACER3,FIG4,ST8SIA4,UGCG,ST3GAL5,CHST9,B3GALNT1,ST6GAL1,ZDHHC17,RNF121,CHPF,ITM2B,CHP1,SVIP,GLCE,HS3ST5,PYCARD,LARGE1,STX16,COPE,RGP1,FAM20C,SLC2A1,KDELR1,TMEM59,QPCTL,LDLRAD4,RAB33A,STK24,CHST10,RIC3,TMEM167B,PLEKHA8,B3GNT2,PITPNB,GAL3ST1,HS3ST3A1,AP1S2,B2M,SEC22B,ATP6V1A,PROS1,NOSIP,SH3GLB1,CHST1 |
| 1.026e-07 | -16.09 | regulation of catalytic activity | biological process | GO:0050790 | 1395 | 498 | 18204 | 5365 |
LEP,FASLG,HNRNPA2B1,CD200,THY1,PIK3CG,PLCB2,PSEN2,HEXIM1,PHB2,WRAP53,ANGPT1,SERPINH1,ADRA1A,SRC,SH3BP4,CHTOP,FAM162A,PTGES3,SERPINI1,LGR4,MIR15A,SERINC1,GPIHBP1,CACUL1,ROCK1,PDCD4,SERPINB11,TCIM,TAB2,IFNG,TIAM1,NOSIP,CAMK1,NBN,RXFP2,RGP1,CCNB1,STIM1,TFIP11,NTRK2,TCP1,NTRK3,MIR218-1,IFI16,CCL1,UBASH3B,TIMP1,CEP85,RGS6,VEGFA,IL23A,RALGAPA2,PRELID1,FGF23,COX17,STK38,CCAR2,STK11,S100A8,RPS7,HDAC6,NKX3-1,FBXW7,TMBIM6,CCL23,ARFGEF1,CD40,RALB,NLRP1,MIR205,SYK,FGF16,DUSP1,BIRC2,EGLN3,TMIGD3,LAMP3,SERTAD1,SERPINB1,RAP1A,HNRNPD,UBE2L3,DUSP22,MIR24-1,ISCU,SMAD3,VSIR,TRIB1,MIR378A,XRCC5,CCL19,P2RY11,DIRAS1,GRM2,CCNF,CAMK2N2,GADD45A,TRAF6,GSKIP,PLN,CCNH,NEK2,CCL4L1,NFKB1,TERT,CHN2,PIH1D1,CRADD,DRD1,TESK1,MAPKAPK5,JMJD8,CHI3L1,SEMG2,CCL2,NHERF1,SERPINA5,TMBIM1,EEF1A1,SPRY1,PRNP,BVES,MIR130B,ERRFI1,USP6NL,HSPD1,PLXNC1,PPP1R17,PPP1R12A,MMP9,CD86,GNAQ,SERPINA1,TOM1L1,ERP29,BAX,TBC1D25,IL12B,LDB2,FGR,YWHAG,ACVR1C,MAGEC2,RPS2,MIR21,UBE2S,CDKN3,LCP2,SFN,DNAJB6,RGCC,MCL1,SMG8,PPP2R5A,RGS10,EMP2,NOS1AP,PRKAG1,NUS1,HP,MIR210,PMAIP1,LPAR2,DSTYK,VAV2,EDNRA,SERPINB9,BCL2A1,SIPA1L1,GPR65,MAD2L2,DRD3,ARHGAP15,TANK,KHDC1,TLR6,IL1B,SIAH2,AIFM1,SERPIND1,TBC1D4,AKT1,TNFSF15,CYFIP2,CCND3,GPX1,CCL24,MT3,CCNI,BAK1,TXN,VDR,HYAL2,GSTP1,CTSK,GH1,TAX1BP3,BOK,SNX18,PDCD10,RFC3,SPRED1,IGF1,APH1A,DKC1,DIRAS2,SOD1,SLC8A1,CARTPT,ATP5IF1,PAK2,SKP1,MSH6,PLAA,MIRLET7B,TGFBR2,CAAP1,CDK12,CCND1,ARRDC3,KIT,GNAI2,RLN2,ANP32B,FAS,ODAM,EIF4A2,MET,LMO4,HPF1,ADRB3,ABCE1,DEFB114,BAD,FGD2,PSMA3,GSK3A,CDK5RAP3,DVL2,LRP6,PLA2G5,CAND1,NR1H2,FGF1,PKIB,PTEN,JAK2,TSG101,BCL2L1,PIP5K1A,TLR4,IFI6,TRIM27,DLG4,MIR590,CCL8,KLF4,CCL11,SPTSSB,RAP2C,PTPN1,BAG2,GHR,ADORA3,TIMP4,PTPRQ,MIR26B,PSENEN,FGFR1,TSHR,POR,NEK7,MIR34A,CLEC7A,ITGA6,TP53,SVBP,GNAI3,LPAR1,TNFSF10,TAF7,RGS1,DIPK2A,CCNY,PAQR3,CAP2,RPL23,CCNA2,PSME2,PPARG,CXCL13,RHOG,PRKCQ,MIR711,CDKN1B,CHRNA7,EZH2,ITK,PRIM2,NCSTN,PSMB9,APOC2,AGAP1,CYP27B1,GAPDH,RBCK1,IKBKB,IL34,LGALS3,SERPINA3,DUSP10,PKIA,AGER,HRAS,PYCARD,S100A10,CAB39,BCCIP,ARHGAP12,HEXIM2,RGS2,CLDN4,EPHA2,FEM1A,DFFA,CORO1C,HMGB1,MAPRE2,PHB1,PPP1R1B,RPS3,MID1IP1,TRAF2,CDKN2C,RFC5,AVPR1B,XCL1,MUL1,ROCK2,CX3CL1,RAF1,TNF,ADIPOQ,TBC1D1,ZC3H15,MAP3K11,DDRGK1,CAMK2N1,ACTB,CAPN1,PLSCR1,CTSD,TBC1D16,NHEJ1,CCR2,F2,CLDN3,TBC1D5,LDB1,PSME1,AZIN2,NLRP3,CCL25,YWHAB,MIR17,TBC1D17,DDR1,RB1,STRADB,NLRP2,TBC1D10C,DAP,SPINDOC,CCL18,CDKN1A,ZNF622,SPHK2,TMSB4X,HSP90B1,RFC4,TBC1D13,PSMD10,CDK5R1,RNF34,MAP3K12,HSP90AA1,SOCS4,SSBP1,TPD52L1,HTR2A,BCL10,INPP5K,PSRC1,CCL3,PDCD5,PRDX3,HSPB1,DUSP19,FZR1,DAPK1,PPIA,CDC20,RTRAF,IGF1R,SFRP1,CCL17,TIMP3,MYC,FERMT2,MMUT,EPHA4,TLR3,CCL5,EFNA3,CST3,ARL6IP5,PPP1R2,PSEN1,LILRB4,RPS27L,CD4,UBE2I,FXN,IL4,SERPINB10,SERPINB6,IFT57,SOCS5,GFI1,HTRA2,PKIG,EFNA5,CAV3,MEF2C,AGAP2,HSP90AB1,NDUFA4,CDKN2D,FKBP1B,FURIN,TNKS,TAB1,CAV1,GREM1,ADRB2,CCL20,PROX1,C9orf72,CCR7,MIR152,FEM1B,PKP4,SPOCK1,DHX9,PTPN22,SOX2,RFC2,RAP2B,PCNA,TGFB2,CHP1,DUSP3,MAP2K3,IL1A,PARM1,DPEP1,DBNDD1,IGBP1,DLG3,HSPE1,BANF1,FIS1,CSTB,CSTA,TOPORS,CBL,S1PR4,CCL21,MIR20A,CSNK2A1,ARHGAP25,DIRAS3,OAS1,CRHR1,FCGR1A,MAP2K1,HGS,MACROH2A1,CAV2,MIR339,FKBP1A,MIR29C,MAD2L1,MMD,CCT2,ATP2B4,RASGRP2 |
| 1.029e-07 | -16.09 | Proteasome | KEGG pathways | hsa03050 | 45 | 33 | 7161 | 2463 |
IFNG,PSMA4,PSMA2,PSMA1,PSMD6,PSME2,PSMD14,PSMB9,PSMA5,PSMB3,PSMD7,PSMB6,PSMB2,PSMD3,PSME1,PSMC4,PSMA6,PSMB10,PSMC1,PSMC5,PSMC3,PSMB7,POMP,PSMB4,PSMB5,ADRM1,PSMD4,PSMB11,PSMB1,PSMA3,SEM1,PSMD1,PSMD12 |
| 1.029e-07 | -16.09 | Proteasome | KEGG pathways | ko03050 | 45 | 33 | 7161 | 2463 |
PSMD1,PSMD12,SEM1,PSMA3,PSMB11,PSMB1,PSMB5,PSMB4,POMP,PSMB7,PSMD4,ADRM1,PSMC3,PSMC5,PSME1,PSMB10,PSMC1,PSMA6,PSMC4,PSMD7,PSMB2,PSMD3,PSMB6,PSMB3,PSMA5,PSMA2,PSMA1,PSMA4,IFNG,PSMB9,PSMD14,PSME2,PSMD6 |
| 1.047e-07 | -16.07 | TCTN2 (tectonic family member 2) | protein interactions | 79867 | 302 | 127 | 19454 | 5460 |
LYPD6,TLCD2,MGAT1,SEC63,VKORC1L1,TECR,VAMP3,B4GALT1,ATP1B3,SDF2L1,GRID1,HMOX2,CSGALNACT2,DEPDC1B,ST8SIA4,YKT6,CERS2,TMEM209,HSPA5,DAD1,FADS2,TEX264,NXPE3,SPCS2,HSP90B1,LEMD3,ARHGAP1,JMJD8,ADIPOR1,SEC22B,TMEM219,RABL3,CLSTN3,HACD2,HYAL2,DNAJC1,ARL6IP5,TMPO,LMAN1,CAMLG,HACD3,SRPRA,PTPN1,ESYT1,POR,SLITRK5,AGPAT1,BRD3,OSBPL8,NUS1,DHRS7,ADIPOR2,EMC4,TMEM199,CALR,DAG1,B9D1,HM13,SRPRB,FKBP8,LPCAT3,NSDHL,RUSF1,RAB1A,EMC2,GALNT12,TMX3,SURF4,POMT2,DHRS7B,CCDC47,PREB,LBR,SPCS1,ATP6AP2,ABHD12,CYB5R3,LMBR1L,GPR89A,LRP12,SPCS3,VMP1,ZMPSTE24,CNIH4,OPRM1,VEZT,TMEM38B,KCNJ8,TMED3,SSR3,RER1,EMC1,B9D2,TLCD1,ITGAV,JAGN1,VAPB,NDUFA5,GOSR2,BET1,TMEM231,GLRB,SEC62,AGK,ASIC1,NDUFS8,SLMAP,RAB31,STX5,BPNT2,PTDSS1,PROS1,DDRGK1,EMC6,EMC8,SEC11A,PDIA6,SCD5,SLC39A7,RPN1,STIM1,VAMP2,PLD3,TMEM39A,EMC10,DIPK1A,FAF2 |
| 1.071e-07 | -16.05 | Toll-like receptor signaling pathway | KEGG pathways | hsa04620 | 104 | 62 | 7161 | 2463 |
CD40,TLR9,TAB1,IL6,TLR5,CCL5,TRAF6,MAP2K1,TLR1,IFNA10,NFKB1,TOLLIP,AKT3,CXCL9,IFNB1,MYD88,IL12A,NFKBIA,IRF3,TIRAP,CCL4L1,CXCL8,IFNA2,TLR3,CTSK,FOS,CCL3,CXCL10,CD80,TICAM2,MAP2K6,TAB2,PIK3R3,TLR2,IRF7,PIK3CA,TNF,CD86,IL1B,IFNA13,AKT2,JUN,STAT1,TICAM1,TBK1,IL12B,MAP2K3,IFNAR1,TLR4,TLR6,MAPK10,TLR8,IKBKB,SPP1,CD14,LY96,PIK3R1,AKT1,IRAK4,TLR7,PIK3R2,CXCL11 |
| 1.071e-07 | -16.05 | Toll-like receptor signaling pathway | KEGG pathways | ko04620 | 104 | 62 | 7161 | 2463 |
CXCL11,PIK3R2,AKT1,IRAK4,TLR7,LY96,PIK3R1,CD14,MAPK10,TLR8,SPP1,IKBKB,IFNAR1,TLR4,TLR6,MAP2K3,IL12B,TBK1,TICAM1,AKT2,JUN,STAT1,IL1B,IFNA13,PIK3CA,TNF,CD86,IRF7,MAP2K6,TAB2,PIK3R3,TLR2,CD80,TICAM2,CCL3,CXCL10,FOS,TLR3,CTSK,IFNA2,CCL4L1,CXCL8,NFKBIA,IRF3,TIRAP,IL12A,AKT3,IFNB1,CXCL9,MYD88,IFNA10,NFKB1,TOLLIP,TLR1,CCL5,TRAF6,MAP2K1,IL6,TLR5,TAB1,TLR9,CD40 |
| 1.076e-07 | -16.04 | FFAR2 (free fatty acid receptor 2) | protein interactions | 2867 | 120 | 61 | 19454 | 5460 |
CCDC167,CLDN4,AGTRAP,EDDM3B,CMTM7,FAM3C,SLC35E3,SMCO4,SYNDIG1,TMEM243,TMEM203,DERL1,SLC39A9,TEX264,SLC35B4,GJB2,SLC38A1,FIS1,FAXDC2,FCER1G,CGRRF1,GNAO1,TMEM229B,CDIPT,PLP1,NRM,SELENOK,GNAQ,UNC50,ERG28,YIF1A,IGF1R,TMEM147,RUSF1,STX8,LEPROTL1,SACM1L,ALOX5AP,TMEM60,NSG1,TNF,GPR37L1,EMC6,SCGB1D1,SLC41A1,FAM20B,TMEM144,PMP22,SLC38A7,CLEC1A,BTN2A2,FXYD6,TMEM11,MFSD5,RPRM,LAPTM4A,TMEM97,CNIH1,TSPO2,ANKRD46,CXCL9 |
| 1.076e-07 | -16.04 | UBE2S (ubiquitin conjugating enzyme E2 S) | protein interactions | 27338 | 120 | 61 | 19454 | 5460 |
TTC4,RBCK1,CDK20,ANAPC11,HNRNPDL,MEPCE,HECTD3,RNF8,CSNK1E,TBK1,FZR1,CDC5L,CDK9,MDM2,UBE2N,SYNCRIP,ATP6V1A,USP15,CDC23,CDKN1B,UBFD1,PPP2R5A,USP2,KARS1,CTNNB1,FBXW7,UBE2D3,UCHL3,HSPA5,XRCC5,RPA3,YAF2,EP300,BIRC2,HSPA8,RNF7,IFTAP,RPA2,STAMBP,ZC3H14,USP6NL,LRRC3B,USP5,UBB,CDC20,UBE2S,NFKBIA,OPTN,ANAPC2,PTEN,SYNGR1,UBE2H,ANAPC4,PDCD4,IGF2BP1,CREBBP,CDC16,AKT1,KANSL3,RNF40,OTUD7B |
| 1.076e-07 | -16.04 | TOMM70 (translocase of outer mitochondrial membrane 70) | protein interactions | 9868 | 120 | 61 | 19454 | 5460 |
TOMM22,CDK7,KLF3,RPA2,IRF3,RPA3,MAVS,AKAP1,HSPA8,ADRB2,PHB2,SLC25A51,STAU1,EYA3,EMC1,ABCC2,TOMM20,FBXL4,TOMM40,H2BC9,BTF3,HTRA2,FIS1,HSP90AA1,TUBA1B,LMBR1L,OPTN,SFXN2,LAMTOR3,RPL13A,MGST3,PARL,ESR2,MTCH2,E2F4,TBK1,TOMM7,SNAPIN,APOO,GDI2,OTULIN,SFXN1,RAB1A,DHX9,USP30,PTGES3,IMMP2L,PTPN5,MARCHF5,CALR,AGR2,TRAF6,HSPB1,COX4I1,AIFM1,PTPN1,KCTD10,COX14,PLGRKT,SLC25A12,EGLN3 |
| 1.078e-07 | -16.04 | RUVBL1 (RuvB like AAA ATPase 1) | protein interactions | 8607 | 540 | 207 | 19454 | 5460 |
VPS72,PELO,SNRPD1,TUBB,RBBP4,ACTB,CUL3,ACO2,HNF1B,PRPF31,BRCA1,RIT1,ILK,PFDN6,PFDN2,FBXW4,CFDP1,TERT,PSMA3,CRY1,SRI,SKP1,ACTL6A,KCND3,PPARG,PHB1,NOP58,INO80E,UBXN6,TAF7,PSMD3,ACTL6B,TERC,TRIP4,INO80C,RBBP7,FLOT1,AHCYL1,RAF1,NGB,NME1,EZH2,SMAP2,TUBA1B,CCNF,PELP1,CFAP298,UBE2I,MSN,NDN,VIRMA,JUNB,SH3BGRL,PPP1CC,AR,FBXO7,DEPDC1B,TXNIP,ZNHIT3,PRPF4,SOD1,MME,RPA3,NCDN,MAVS,FBXW7,SMC4,ATG16L1,STOM,LMNA,TTI2,RCHY1,EEF1AKMT3,AIFM1,WDCP,H2AZ1,ASNSD1,CDK9,HDAC6,ECD,CRBN,SMG9,TFPT,SLC25A10,FAF1,PPP1R12A,HINT1,IGF1R,HSD17B10,DNAAF10,TSSC4,HUWE1,PTGES3,FBXO25,EEF1A1,MAP2K3,ACTR2,DMAP1,PPME1,ZNHIT6,PRMT5,TRIM29,SNRNP40,MATR3,POLR2B,MYC,CREBBP,BTF3,PSMD1,PELI3,LAMTOR1,SMARCD3,HIRA,HSPA8,HDAC5,STAU1,UFL1,SRSF2,PPT1,FDFT1,PIH1D1,EED,SUMO2,DYNC1I2,MEAF6,WWP2,CTNNB1,DDRGK1,XPO1,AGR2,TNFSF13,HSPB1,PABPC1,RUVBL2,RPAP3,EWSR1,RUVBL1,VDAC1,KRAS,MED9,MAX,TNPO2,SOX2,TUBA1A,ISG15,SMNDC1,H2BC1,TUBB4B,MOB3C,MTA2,MACROH2A1,ADRM1,NOPCHAP1,MORF4L1,SLC25A1,SMARCA5,SPOP,UBE2H,ATP1A1,BAP1,RNF113A,HSPA5,ING5,NTPCR,CFTR,CDC42,POLR1D,RPA2,HEXIM1,UBE2M,PREP,TMED9,CAND1,FZR1,SPPL3,PLG,CDC5L,DKC1,TMPO,KLK3,FAM20C,B9D1,CSNK2A1,COPS5,SHC1,SNRNP70,USP15,LSM3,KPNA1,SMG8,TAF9,PSME1,SNIP1,MAP1B,METTL18,KPNA2,DYNC1I1,FKBP8,MEPCE,PDRG1,INSIG2,ZNHIT1,H2AX,DDX42,TFCP2,NUPR1,PSMC3 |
| 1.081e-07 | -16.04 | cellular oxidant detoxification | biological process | GO:0098869 | 91 | 51 | 18204 | 5365 |
HBB,GSTK1,GPX5,TXNRD3,SOD1,TXNRD2,GSTO2,HBE1,GPX4,NQO1,GSTO1,SESN2,IPCEF1,GSTA1,SELENOW,MGST2,HP,GPX3,CCS,HBM,SRXN1,ALOX5AP,MGST3,PRDX4,CLIC2,GSTT1,GPX2,PRDX6,SELENOT,SELENOS,PRDX2,GPX6,PRDX1,GPX7,SOD3,GSTM2,GSTP1,TXN,TXNDC17,HBA1,CYGB,TP53INP1,SELENOF,TXNRD1,GPX1,PTGES,PRDX3,MT3,SOD2,ALB,UBIAD1 |
| 1.111e-07 | -16.01 | immune system process | biological process | GO:0002376 | 1991 | 688 | 18204 | 5365 |
BAP1,POLR3F,PMAIP1,IREB2,TCF21,LIG3,SELL,SIN3A,IFI27,LYAR,VAV2,SERPINB9,AQP4,LILRA2,CXCL3,INHA,EMP2,DNM2,JAK1,LST1,RGCC,CD99L2,LEAP2,MAEA,SYNCRIP,RSAD2,CSK,SPG21,PI3,CAMLG,STOML2,CXCL9,FOXP1,IL12B,MX2,ALCAM,RNASE6,POLR3B,RPS17,FGR,RPL39,PELI1,IFNGR1,PNP,CD79B,TRIM34,HSPD1,LACC1,CD34,RAB27A,DEFB114,STXBP1,JAK2,TIRAP,BST2,STAT1,IRAK1BP1,ATP5IF1,MSN,TMEM229B,CRKL,UBE2N,LMO4,TNFSF13,CDC42EP2,CD14,EIF2AK2,POLL,HYAL2,SHLD1,CTSK,CTNNB1,SP2,CCL24,TMEM106A,EP300,CD164,KARS1,PIK3R3,SEMA3C,ISG20,TANK,AKAP17A,TNFSF15,TFE3,SEMA7A,KDELR1,LILRA1,EXOSC3,MOG,FBXO7,TICAM1,BMPR1A,MIR181C,SFXN1,RPS24,IFI16,TLR8,NBN,EIF2B5,ACTR2,BPIFB1,PQBP1,IRF1,PRKRA,RAB8B,SFTPA1,LGR4,TMEM45B,SLC39A3,IFNG,FAU,SERINC3,FGL2,HEXIM1,PHB2,RNASE4,SQSTM1,LEP,CD1A,TRIM21,EPS8,EXT1,TNFSF12,PNMA1,SRC,NFKB1,KCNJ8,IL15RA,RNASET2,ARG2,CCL4L1,HCLS1,SLC11A2,PSPC1,TASL,PML,SFTPD,CCL19,TLR5,RAB35,CTLA4,NINJ1,ADGRE2,CD38,CD2AP,TLR10,TICAM2,TSPO2,TRAF6,PIK3AP1,KLRC2,DEFB115,TUSC2,SELENOK,TRIM62,LMBR1L,SARM1,IFIT2,SMAD3,FCGR2B,PKNOX1,PSMA1,CLU,OTULIN,CCL23,CBFB,CD28,TAX1BP1,ZYX,FKBP1B,POLR3H,ST3GAL1,MEF2C,MSRB1,MCOLN1,SOCS3,CAV1,TRIM11,IFNB1,RC3H2,CLDN1,IDE,APOBEC3F,PSEN1,LILRB4,CD4,PLPP6,PTN,TRIM26,ZMPSTE24,SLPI,IRF9,IFIH1,ALKBH5,APOBEC3G,DAPK1,IFNAR1,ITM2A,G3BP1,SOS2,NFIL3,HSP90AA1,SMAD5,TNFSF8,APOBEC3D,CD83,BPIFB3,SASH3,APLN,PELI3,PRKCB,CHGA,FOSL2,LTA,OAS1,CRHR1,TRAF3IP3,CD151,IRF7,NLRP6,H2BC11,USP14,ATP1B1,IFI35,CCL21,TRIM22,FAM3A,DEFB116,FGF10,IRF6,IL2RG,NCK1,TF,POLB,NOTCH2,SRPK2,CRIP1,TGFB2,IL1A,CLPB,FCN2,FOLR2,RPL22,WFDC13,JCHAIN,CCL20,TNFSF18,CREBBP,PTPN22,IRF2,TTC4,C1QC,NCSTN,YTHDF2,EZH2,IL3,CHRNB2,ITK,RAB32,IL7,PTGDS,EPO,SRP54,GAPDH,EGR1,IKBKB,IL34,PPARG,JAML,LIPA,RACGAP1,PTGER4,F11R,SLA2,PRKCQ,CLEC7A,IL21,AZI2,ITGA6,IL13,H2BC12,SLC39A7,CXCL8,RGS1,MADCAM1,SPAG11B,CTSC,SPPL3,IDO1,CD1E,DCLRE1C,PTPN11,CCL8,CCL11,MICB,TOMM70,TRIM27,LRRC8A,NONO,CDK6,FOXI3,AZGP1,RAC2,PRDX2,PLPP4,NKAP,ADORA1,RAG1,TRIM23,CGAS,INPPL1,ICOS,VAMP2,TNFRSF14,CXCL10,APOBEC3B,F2,CCR2,RHOH,TMEM126A,CD1C,PSME1,MRGPRX2,DBH,CX3CR1,TRAF2,NMBR,LY96,TRIM6,VAMP7,CCR3,IL10,CACNB3,RAF1,CXCR4,GTPBP1,BATF,AGER,PYCARD,HRAS,MBL2,CD1D,HMGB1,YTHDF1,CXCR1,RAB6A,H2BC1,MPIG6B,CDC42EP4,CD80,HP,TAPBP,OPTN,NCAPG2,GNL1,RIGI,GPR65,MAD2L2,ADSS2,WNT10B,NMI,SAR1B,CLEC6A,LCP2,DHX16,IFNA2,TLR9,IFNK,TNFRSF1B,SH2D1A,PSMB11,WFDC5,IL6,TRAF3IP2,BAX,PYDC2,CD86,IFNA10,NKX3-2,G3BP2,TREML1,DDX1,FCER1G,CXCL14,DAPK3,VPS26B,TMED1,MATR3,MX1,FOXP3,CD274,PRKCE,CPLX2,CDK5RAP3,SYVN1,LCP1,CCL28,B4GALT1,PAK2,MSH6,IL2,TGFBR2,MIRLET7B,LAT2,SOD1,KLRD1,FCAR,TOLLIP,RPL13A,XBP1,KIT,TUBB4B,FAS,BAK1,RHAG,TNFAIP3,TOX,CCND3,CXCL11,UBE2W,NFKBIA,ROMO1,CALR,FBXO9,TLR6,NCR3,IFNA13,SLAMF9,PPP3CA,TAPBPL,IL1B,AKT1,CD248,VEGFA,IL23A,SAMHD1,LYZ,IL15,TLR1,SIT1,OPRK1,KLF1,PIK3R2,TPD52,TRIM10,PIK3R1,OSM,CCL1,CTNNBL1,ROCK1,CAMP,IL17F,PIK3CA,CD47,PAFAH1B1,TCIM,ICAM1,CD58,CNIH1,CD40LG,FASLG,TFEB,PDE4B,PIK3CG,REG1B,THY1,IL18,PRDX1,TRIM35,CACNB4,SEMG2,CCL2,MAP2K6,IL2RA,TUBB,VAMP3,DPP4,BPGM,TBK1,XRCC5,APOBEC3A,SNAP23,SLC12A2,CD1B,G6PD,RARRES2,TLR2,PDCD1,TMOD3,TRIM32,GPAM,YES1,CMTM7,LAMP3,RAB33A,CD2,S100A8,HSCB,HDAC6,TRIM5,STK11,APOBEC3C,NLRP1,CCR4,CH25H,SYK,CD40,SWAP70,TYROBP,NCR3LG1,CHID1,WDR37,CCL27,MAVS,PDP2,CD46,MFSD6,MIR146A,CD81,NLRP9,PSMB10,IL20RB,IL4,MYD88,IGF1R,CCL17,FTH1,PPIA,CDC42,CNPY3,CCL5,ADD2,ABCB9,RPS14,TRIM68,TLR3,IL2RB,DEFB124,RAB4A,IRF3,STX8,BTN2A2,CSF2,AKAP1,SLC48A1,RNF34,MIF,CCL3,LILRB1,BCL10,SCG2,IL12A,MRC1,MAP2K1,HDAC5,CCR1,IRF8,MAP3K14,CCDC92,REG1A,FCGR1A,TLR7,FKBP1A,IL5,DHX15,TRIM29,SKAP2,LTBR,EFNB1,BECN1,IGBP1,DLG1,DNAJB9,CYBC1,IL1R2,STAT2,NDFIP1,CBL,S1PR4,OLR1,CCR5,RAB29,LTB,DEFB1,OTUD7B,JAGN1,IL18BP,TRIM8,EIF2B3,CD209,PLD3,DPEP1,HRH2,RNF8,ISG15,STAT6,CCR7,CCR6,UAP1,HCFC2,HAND2,CXCL1,RAB3B,CXCR6,RABL3,VAMP8,DHX9,B2M,PSMB9,ATAT1,EIF2B2,HMCES,LGALS3,GAPT,SDHAF4,TRIM15,CYP27B1,RBCK1,RAB3C,SLC15A2,CXCL13,FCMR,UFL1,APOBEC3H,CD247,CD3G,NQO1,HELLS,IRAK4,CHMP5,PPP2R1A,TNFAIP8L2,LEPR,ENDOD1,TNFSF10,ST6GAL1,TP53,IFI6,TLR4,SEC14L1,MSMP,TMEM33,ACKR3,PPIB,LILRA3,CASP4,CCL18,CITED1,RB1,SLC25A5,NLRP2,GPR89A,TNFAIP1,CYP11B1,TBC1D10C,LSM14A,NHEJ1,AIF1,TIFA,IRF4,MAPKAPK3,CTSD,PDCD1LG2,CKLF,GJA1,CXCR3,CEBPG,CCL25,NLRP3,FCGR2A,TESPA1,PHB1,PDE12,PDIA3,TNF,DEFB121,XCL1,RBPJ,CX3CL1,ITGB8,IL1RAP,GPR15,PLG,TOP2B,CXCL12,BCL6,HFE |
| 1.125e-07 | -16.00 | STOML2 (stomatin like 2) | protein interactions | 30968 | 248 | 108 | 19454 | 5460 |
FAF1,RAB1A,SFXN1,EMC2,DNAJC30,FASTKD5,PSMB10,RIGI,ATP5PB,MRPL11,APOO,METTL15,NDUFS3,GFM2,SYNCRIP,SSBP1,COQ8A,COQ10B,FZR1,ATP5PD,LMAN1,PRELID1,SLC25A46,ESYT1,CHCHD1,TMEM70,USP15,MAIP1,RPA3,PNO1,SIRT7,GFM1,MRPL40,SLC25A51,HSPA5,COQ8B,CFTR,RPA2,METTL14,FGFR1,STOM,MTRES1,HAUS2,CCNF,MOB4,PTPMT1,UQCRQ,VIRMA,ATP5F1A,TUFM,RC3H2,NRP1,DNAJC19,UBE2H,NDUFA4,EWSR1,OPA3,HINT2,COX8A,VDAC1,PDHA1,CHMP4C,CYB5B,MYEF2,PHB1,GATD3,ADCK1,EGLN3,RMND1,HSP90AB1,MTRF1,PSMD3,RAB5C,DDRGK1,ACP6,STK4,RHOG,AGR2,MRPS26,CBL,EXD2,HSPA8,RABAC1,PSMA3,HADHA,PMAIP1,EMC1,UFL1,HSCB,PHB2,SLC25A3,TACO1,DLST,CCDC90B,CYB5R3,MTM1,MATR3,ACTB,TENT5C,ESR2,MYC,MTG2,AUH,FMC1,CUL3,PMPCA,RIOK2,ILK |
| 1.126e-07 | -16.00 | ACLY (ATP citrate lyase) | protein interactions | 47 | 311 | 130 | 19454 | 5460 |
PDIA3,PRPF19,IFI16,CTNNB1,AGR2,TRAF6,PSMD10,AHSA1,HNRNPD,MAGED2,ATXN10,CCT7,DHX15,MAX,RAF1,MSX2,PPP2R1A,ISG15,GABARAPL1,TRAF2,CHMP4C,EZH2,MOB3C,HGS,CCT8,KLHL25,HNRNPA2B1,PCNA,RUVBL1,HNRNPF,SAR1B,PAK6,CBLL1,MCM6,PSMD12,CUL2,HNRNPC,CUL3,USP13,MYC,SNRPB,BAG3,PSMD14,BRCA1,TFDP2,CCT2,RAN,LMBR1L,ACTB,PSMD6,TUBB,ATP5F1B,TNPO3,PRKAB1,RPE,NEK7,PPT1,PIH1D1,ARCN1,EP300,HDAC5,CRY1,HSPA8,STAU1,PPP2R2C,EMC1,UFL1,PYGB,KARS1,GAPDH,HDAC6,SHC1,NME2,RPS2,TFE3,SDHB,CD274,STT3A,CAND1,CCT5,TP53,MAP1LC3B,CBX3,PSMC3,NUPR1,RAB1A,ABCE1,ERO1A,HNRNPK,TOLLIP,CSE1L,KPNA2,NUP107,HUWE1,CAPZA1,PTPN11,MAT2A,AR,USP14,SPOP,UBE2H,ATP1A1,CTTN,CTNNA1,RPS3,CCNF,OPTN,GANAB,KCTD9,VIRMA,CAPN1,ARHGAP1,CFTR,LMNA,RPA2,UBE2M,HEXIM1,SIRT7,BAP1,HELLS,INPPL1,RPA3,DERL1,SQSTM1,SYVN1,SMC4,NUCKS1,FBXW7,GTF2I,MARS1 |
| 1.136e-07 | -15.99 | MAT2A (methionine adenosyltransferase 2A) | protein interactions | 4144 | 195 | 89 | 19454 | 5460 |
RNF7,PIH1D1,CSNK1A1,ACSS2,PRDX3,UFL1,PEBP1,HSPA8,DDX5,YAF2,CCT2,RIT1,MYC,PSMA4,CUL2,CUL3,TMEM213,RPL35,TUBB,MAT2B,AP2M1,EZH2,CHMP4C,HGS,OTULIN,TUBA1A,EEF2,KRAS,SAR1B,PABPC1,CCT8,VCPIP1,ARMC8,IFI16,XPO1,DHX15,TMEM237,DUSP6,PSMB5,PHB1,ARHGAP25,RPA2,UBE2M,HNRNPH3,LEMD3,ATG16L1,CAPN1,EEF1E1,CDC42,CFTR,MARS1,BAP1,UGDH,SOD1,RPA3,CSTB,SQSTM1,UBE2H,MAT2A,FBXO7,ARHGAP21,TUFM,SMURF1,VIRMA,RPS3,CCNF,CTNNA1,UBE2I,MSN,TRIM24,CCT5,DUSP1,CTNNBL1,HNRNPK,MEPCE,MAP1B,ERO1A,HSD17B10,KARS1,EMC4,COPS5,ELOC,FZR1,VCPKMT,PRNP,G6PD,SDHB,DFFA,PSMB1 |
| 1.147e-07 | -15.98 | NIPSNAP2 (nipsnap homolog 2) | protein interactions | 2631 | 149 | 72 | 19454 | 5460 |
ESR2,RHOJ,MGST3,RALA,PYGM,GANAB,VDAC2,GNG12,ATP1A1,NRP1,LAMTOR1,BTF3,CUL3,AUH,AATF,GABARAP,PHB2,PDHB,HADHA,SQSTM1,TRIM5,PGK1,PML,RPA3,CYC1,SCLT1,SAMM50,RPA2,VAPB,COX6C,ATP5PO,GABARAPL2,CRAT,PGRMC1,SEC22B,ATP5PD,EGLN3,PRNP,RHOH,CYB5A,MAP1LC3A,PHB1,COX4I1,SRSF1,FKBP4,CTNNB1,ATP1B1,KLHL22,XPO1,MARCHF5,COX5A,SLC25A46,MOV10,PTGES3,COX7B,TRIM37,DCP2,COX8A,RUVBL2,NDUFA4,SFXN1,HSPD1,SLC25A24,MTA2,SF3B5,RPN1,MAP1LC3B,GABARAPL1,DDX39A,WBP11,ACTN4,ATP5PB |
| 1.154e-07 | -15.97 | ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3) | protein interactions | 478 | 220 | 98 | 19454 | 5460 |
SIGLECL1,ADORA3,KBTBD4,CHRM3,FAM162A,MGARP,TNFSF8,ATP1A2,RAB1A,MAP1B,LRRN4CL,SLC2A1,FAM187B,NXT2,EI24,ATP1B1,PRNP,KCNMB2,ST3GAL5,ILVBL,SRPRA,TREML1,DECR2,LHFPL4,NAA30,FA2H,ARL4D,CTDSP1,GPR35,HEXIM1,SEC22B,HCST,KLRD1,HSPA5,TMX2,IRF3,SNX14,ATP1B3,RIC3,ATP1A1,TYROBP,LYPD6,DHRS13,ALG2,CHRM4,SYNGR1,DTWD2,STK16,COX4I2,LGR4,ARL5B,VDAC1,HS2ST1,MRGPRX4,NDUFA4,CD83,AKAP14,PRND,UBE3A,FXYD6,VPS4A,FAM174A,ICAM2,CX3CL1,RAB1B,AGK,RAMP3,CCT7,OPRL1,SSR2,MPDU1,ATP6V1A,SLC25A3,TOMM22,TMEM231,SEC62,DIO3,SLC15A1,RER1,TACR3,CXCR4,TSPAN15,TACR1,CGRRF1,KLK5,THTPA,ST3GAL1,GPBAR1,PRMT6,GPR17,LYZL6,GPNMB,VDAC2,LMBR1L,S1PR4,EDNRA,TNFRSF9,GPR173 |
| 1.159e-07 | -15.97 | TOLLIP (toll interacting protein) | protein interactions | 54472 | 349 | 143 | 19454 | 5460 |
WBP2,ACTMAP,ARRDC3,RLIM,HADHA,HSPA8,BIRC2,NOP53,SRI,YTHDF1,PAFAH1B1,TOM1L2,ATP5PO,MYL6,RTF2,EIF4B,LMBR1L,BST2,TUBB,TAX1BP1,SIAH1,NDFIP1,ESR2,NCKAP1,TOM1L1,PSMA4,TOMM40,LDB1,MYO6,CCT2,ZYX,FAM168A,SLC39A7,PCNA,TRIM21,G3BP1,ZBTB16,TFG,COPS4,POLDIP3,RNF26,RAB18,CCAR1,ODAM,RANBP1,MSX2,TMEM59,SOX2,VPS33A,PLD3,HGS,SDC4,TNIK,TSG101,MAP1LC3A,ZHX1,TTC9C,PEG10,RAB5C,MAP1S,CDIP1,CLPX,PDIA3,CTNNB1,XPO1,PPFIBP1,TRAF6,DRG2,IKBKB,PPP3CA,SPCS2,SQSTM1,TLR2,IL1RAP,CLU,AKR7A2,DDIT4L,PSMC4,RBFOX2,FTH1,UBLCP1,HSP90B1,STOM,SDCBP,HECTD1,EIF2AK2,CCNF,CREB1,RPS3,RTRAF,NMI,SRPK2,GNAI2,DYRK1A,TECR,RSPH1,ZMYND19,RETSAT,USP14,AR,NTAQ1,RUNX1,TLR9,IVNS1ABP,STN1,SORD,PNPO,AP2A1,ATP1A1,BHLHE40,ZNF787,PPP1R12A,TLR4,SNAP23,TAGLN3,RING1,TOLLIP,TOM1,NOC4L,AKAP12,NEDD8,VTA1,DDX39A,IK,GUCD1,RBM34,TFRC,TLR3,DMAP1,RP9,APEH,MRPL49,TBC1D4,PSMB1,RAP1B,PRNP,CAV1,SLC38A2,RBM17,GRSF1,SMCHD1,SNRNP70,SLC2A1 |
| 1.170e-07 | -15.96 | PKM (pyruvate kinase M1/2) | protein interactions | 5315 | 417 | 166 | 19454 | 5460 |
DNAJB6,BAX,HSP90AA1,ICAM1,PSMD14,CYP1A1,BRCA1,BAG3,AK3,BTF3,PDE4B,LDHB,CUL2,CUL3,MYC,LGALS3,TUBB,PRDX2,ENO2,TRIM44,GNG12,AKR1A1,ANXA7,PIH1D1,ACAA2,CDKN1A,PGRMC1,LYPLA2,RPP14,FBXL4,STAU1,FXR2,EMC1,UFL1,PSMA3,EP300,CRY1,HDAC5,TRUB1,HSPA8,DDX39B,ARMC8,HSPB1,MGMT,HNRNPD,TST,AGR2,AK2,DDRGK1,CTNNB1,HNRNPA1,DIRAS2,WWP2,PDIA3,IFI16,HSP90AB1,EGLN3,PPIA,SUMO2,TRIM35,HNRNPL,PHB1,FOLR1,MOB3C,PPID,NME1,CHMP4C,RPN1,EZH2,MSX2,ISG15,B3GNT2,ANP32A,RAF1,SAR1B,TRIM37,SEMA4C,KRAS,TNF,UFM1,UBE3A,EWSR1,ZC3H7A,MKLN1,HNRNPA2B1,UBE2H,CDC73,TRIM23,RC3H2,AR,IFNAR1,FBXO7,CFL1,GSTK1,VIRMA,CD47,TXNDC12,LDHA,KCTD9,NDN,ACAT1,PTEN,CYRIB,EIF4A3,QNG1,STUB1,CCNF,UBE2M,HEXIM1,FGFR1,WWP1,IDH2,RPA2,CFTR,SNRNP27,SUMO1,ATG16L1,CCR4,PRDX6,RNF113A,PGK1,BANF1,PML,BAP1,HELLS,DVL2,RPA3,FOXP1,CNN3,KPNA1,NXT2,NME2,MPG,GAPDH,CD81,COPS5,HDAC6,EMC4,CDK9,MDM2,FZR1,RAP1B,OLFM2,SRP14,CD274,RAD23B,RNF8,PPME1,SOD2,CAPZA2,TNFAIP8L1,TFCP2,TMEM205,H2AX,EEF1A1,CDK4,TP53,SMN1,MEPCE,HNRNPK,TRIM63,TGFBR2,HUWE1,PSMA5,EMC2,FAF1 |
| 1.172e-07 | -15.96 | XRCC5 (X-ray repair cross complementing 5) | protein interactions | 7520 | 492 | 191 | 19454 | 5460 |
ILF2,FBP1,POLL,VRK1,HUWE1,MSH6,MDC1,VTA1,HSD17B10,HDAC6,TOP1,PRNP,POLE3,NHEJ1,H2AZ1,SMAD3,METTL14,GOLGA5,JUP,TPT1,NFYB,ATG16L1,CDK7,EIF3J,NUCKS1,DGCR8,NF2,SIRT7,RPA3,SOD1,PPM1G,MME,HOXC4,CDC16,AR,USP14,NDN,VIRMA,CCNF,OPTN,PTEN,TRIM24,UBE2I,GANAB,NGB,CHMP4C,EZH2,VPS33A,RNF126,RBPJ,POLR2D,B3GNT2,ZNF263,NAA15,RAF1,TRIM37,SAR1B,SSRP1,MORC2,PCNA,HNRNPD,AHSA1,HMGA1,HNRNPA1,LRWD1,PHB1,EMC9,PPARG,KCND3,SUPT4H1,UCHL3,COIL,PSMA3,TERT,CRY1,BRCA1,RIT1,BAX,PAXX,CUL2,CUL3,NFYA,SAMHD1,USP5,UBE2S,SNRPD2,RNF8,NUPR1,FURIN,TP53,NDST1,H2AX,CSE1L,H3C1,MEPCE,PHF1,DHX9,ABCE1,RPL24,H2AC4,KARS1,CSNK2A1,FZR1,TMPO,SSBP1,HBB,RNF146,WWP1,RPA2,UBE2M,HEXIM1,CFTR,NBN,BAP1,ORC6,DERL1,RNF113A,RC3H2,CHRAC1,SPOP,UBE2H,ZBTB38,ATP1A1,SMARCA5,SLC25A1,PRKACB,ADRM1,KCTD9,SRPK2,SMURF1,ROCK1,LIG3,DCLRE1C,MACROH2A1,EIF2S2,SUPT5H,TOP3B,MAX,MSX2,ISG15,SOX2,VDAC1,HMGN4,KRAS,PELI1,TOP2B,EWSR1,RUVBL2,AGR2,YWHAB,HSPB1,CBL,RIOX2,WWP2,IFI16,DDRGK1,CTNNB1,XPO1,DYNC1I2,SUMO2,HNRNPL,EIF2S1,PGR,MACROD1,EED,PIH1D1,EIF4B,MTF1,NEK7,STAU1,UFL1,XRCC5,RFC4,CD40,DDX39B,YAF2,EP300,HDAC5,HSPA8,ATG3,LAMTOR1,ICAM1,HNRNPC,MYC,COX6B1,BTF3,MATR3,APEX1,ESR2,CMTR1,IRF2 |
| 1.175e-07 | -15.96 | positive regulation of apoptotic signaling pathway | biological process | GO:2001235 | 143 | 72 | 18204 | 5365 |
SOD1,NACC2,BECN1,FIS1,PAK2,LTBR,PPP2R1A,CTNNA1,FAS,MCL1,HTRA2,BAD,G0S2,MIR198,PMAIP1,FAF1,MIR210,CRADD,MIR16-1,PML,RBCK1,SIAH1,ING5,NHERF1,EEF1E1,BMPR1B,CAV1,IFNB1,JAK2,PYCARD,RPL26,PLEKHF1,DDIT3,TLR4,STK3,TRAF7,ATF3,NKX3-1,FBXW7,TLR6,MIR449A,RPS7,S100A8,BCL10,TPD52L1,TNFSF12,MIR186,MIR26B,PDIA3,RPS3,NCK1,MIR15A,UBB,NUPR1,LTB,BAX,MYC,HYAL2,SFRP1,TRAF2,CTSK,FLCN,MSX1,PRKRA,SERINC3,STK4,CTSC,BOK,TP53,PEA15,TNF,TNFSF10 |
| 1.186e-07 | -15.95 | NCLN (nicalin) | protein interactions | 56926 | 176 | 82 | 19454 | 5460 |
RPN1,EZH2,RHOBTB1,RND3,CCDC47,RAF1,TOP3B,CBLN4,APOO,LBR,DNAJC30,TMEM33,HUWE1,TNF,RIGI,RPL17,EMC2,TMEM147,SEC11A,SLC2A1,RHOG,CDK5RAP3,DRG1,PEX3,RB1CC1,PTDSS1,FAM20C,EMC4,RAB3D,EI24,DDRGK1,COPS5,EMC6,RHOH,ARF6,FBXO32,COX4I1,PHB1,RAC2,RPA2,ARL15,PGRMC1,CDC42,RND2,TMEM106A,FBXW7,RPL4,STAU1,UFL1,EMC1,COIL,TMEM106B,EXD2,RHOU,TMX2,RPA3,DERL1,AKAP1,EP300,SPCS2,RHOB,SPCS3,CKB,CALU,UBE2H,NRP1,ATP1A1,CUL3,TMEM38B,LRRC8C,RHOJ,SPCS1,FBXO22,SEC63,ESR2,RPL19,VIRMA,LMBR1L,SELENOT,CCNF,SEC61B,SERINC1 |
| 1.202e-07 | -15.93 | Small_GTPase_Ras-type | interpro domains | IPR020849 | 21 | 18 | 18521 | 5414 |
HRAS,RAP2A,RALB,DIRAS3,RAP2B,RALA,RIT2,DIRAS2,RAP1A,RIT1,RRAS2,DIRAS1,RHEB,RAP2C,ERAS,RAP1B,MRAS,KRAS |
| 1.219e-07 | -15.92 | NOP56 (NOP56 ribonucleoprotein) | protein interactions | 10528 | 556 | 212 | 19454 | 5460 |
RPL7A,SUB1,AKT1,RC3H2,UBE2H,CALU,IGF2BP1,ATP1A1,ZNF330,PSPC1,RPS3,FGFBP1,RBMX2,EIF2S2,SRPK2,GTF3C4,AGO1,RPA2,KLF4,BAP1,RNF113A,EXOSC4,WDR3,HSPA5,DPP4,COPS5,CSNK2A1,CHCHD1,SNRNP70,H2AC4,RPL24,RPL10A,KPNA1,RPS2,RPL32,PNMA3,NKAP,RPS16,CAND1,SURF6,LMAN1,DKC1,TP53,SRFBP1,KBTBD4,BMPR2,DISC1,RBM34,RP9,NUPR1,DHX9,RPL3,IMP4,RPL17,H2BC14,MEPCE,MYC,BTF3,THAP7,FTSJ3,H1-10,ATG3,CIRBP,POLR1B,SERPINH1,NSA2,DLST,GTF2F1,FBXO22,SNRNP40,RPL10,APEX1,MTF1,RPL27A,INSYN2A,TRMT112,RFC4,EP300,STAU1,EMC1,UFL1,RPL6,RIOX2,IFI16,DDX50,DDRGK1,PPIB,AGR2,EED,LYAR,SUPT5H,EEF2,RPS7,SOX2,DNAJC25,H1-3,NCSTN,TUBA1A,HDAC11,RPL18,TOP2B,ABCF1,RPL31,VDAC1,KRAS,RPS4X,TUFM,DNAJC8,HMOX2,KPNA6,RUNX1,RPL26,ENO1,OPTN,CCNF,UBE2I,PTEN,RPS12,RTRAF,GANAB,RPL13A,RPL22,DEK,RPS14,KLF12,HSP90B1,METTL14,LMNA,RPLP0,RARS1,SIRT7,RPA3,PPM1G,MTDH,FBXW7,RPL4,DGCR8,AATF,BRIX1,MOV10,GRSF1,CALR,MPHOSPH10,BRD3,KRR1,ACTA2,RPL12,SRP14,TOP1,RPL35A,ZBTB2,TRIM6,RPL15,EEF1A1,MLLT6,ILF2,NKRF,TCOF1,EMC2,HSD17B10,RPL23A,SMN1,RPS13,CUL3,NOP16,RAB11A,RFC5,PRPF31,BRCA1,RIT1,RPS5,PELO,RPS9,ZMAT2,RPL37A,RPL19,PRRC2A,MAD2L2,MFAP1,NKAPD1,CCDC86,NOP53,UCHL3,COIL,PDIA3,HNRNPA1,DDX23,RPL23,MED4,MRTO4,FBXO32,RPL8,RPL9,RPL7,NOP58,DHX15,E2F4,RAF1,CHMP4C,EZH2,RPN1,RPS11,PPAN,SCYL2,SLC25A5,RPS24,ERP29,ASF1A,DHX16,SSRP1,RFC3,RFC2 |
| 1.222e-07 | -15.92 | RHOB (ras homolog family member B) | protein interactions | 388 | 832 | 301 | 19454 | 5460 |
EPHA2,LRP6,PIP4K2C,DEPDC1B,RACGAP1,TECR,SH3BP4,UBB,FERMT2,GNAI2,F11R,RPL13A,YES1,GANAB,SLC11A2,MSN,UBE2I,RPS12,ACAT1,VAMP3,GAB1,HYCC1,CTNNA1,TUBA1B,OXSR1,JUP,CTDSP1,PICALM,STOM,SLC12A2,SIPA1L1,CNP,UBA52,SNRPN,PIP5K1A,ARHGAP1,SEC22B,PIAS1,UTP23,TMEM209,CDC42EP4,IL1RAP,YKT6,NF2,SLC7A1,B2M,PDHB,PIK3R2,ITGA2,INPPL1,LRRC8D,OSBPL8,SLC2A1,EXOC2,TIAM1,ESYT1,SLC35A5,RAB23,DAG1,ATP1B1,RELL1,CAV1,ARF6,ALCAM,PRNP,DLGAP4,CDCA3,C2CD2,HACD3,EHBP1,ILF2,ALPL,PDE6D,CASK,ZDHHC8,KRIT1,SLC29A1,RPL15,TMEM126A,CMPK1,CTNND1,FASTKD5,FARSA,SEPTIN7,CCNY,SNAP23,IGF1R,SHISA2,HSD17B10,EMC2,STX8,RAB1A,NSDHL,DLG1,GARRE1,SFXN1,SCFD1,SLC7A11,MYO6,MRPL16,MAP3K21,TOMM40,NIBAN2,CUL2,PKP4,RAB11A,CHCHD3,PRDX2,LRRC8A,LAMTOR3,AP2M1,FZD6,CLDN3,LRRC1,FAM91A1,ARF1,GNG12,SLC25A3,MYL6,ATP5PO,EHD1,PPP1CB,FAM234A,NOTCH2,DAAM1,PSMC1,STX7,TSR3,NPTN,ATAD1,RP2,CLDN1,HADHA,PRKD3,CXCR4,UPF3B,RTKN,C2CD2L,RASSF8,LRRC57,PRDX1,RAB32,MTRF1,PIK3R1,PPIA,ERLIN1,TMEM237,WDR44,OCRL,SPTAN1,GJA1,NEO1,PLEKHO2,SPRED2,WDR6,MRTO4,PHB1,STX12,RPS11,PGGT1B,ITGB5,VAMP2,RPN1,PCDH17,RPL29,PPP2R1A,TULP3,DCUN1D3,IFNGR1,MARCKSL1,DLG3,FLOT1,SEMA4C,ACVR1B,JAK1,PLCB1,SCYL2,ATP1A1,ATP1B3,RAP2C,ARHGAP21,CNNM4,SLC6A6,RAB2A,SLC25A1,NDUFAF2,CCNB1,RPL7A,ROCK1,SMURF1,SRC,RALA,MACROH2A1,STX10,UQCRC2,NECTIN2,CSNK1G3,SDCBP,CDC42,SPTBN1,FTSJ1,ARFIP1,RAB9A,TNFAIP1,BAP1,LRP10,KPNA1,NUS1,SLITRK5,LANCL2,CD81,LMAN1,SLC38A2,STX6,ARL6IP5,VTI1B,FCHO2,PLSCR3,FLRT2,SLC39A10,RAP1B,STT3A,ACSL4,ITGA6,UGCG,SGIP1,CERK,EXOC3,TFRC,CCM2,RBM34,BMPR2,NHERF1,UBIAD1,ARHGAP12,SNAP29,RAP1A,SLC6A8,RDH11,AKAP12,CSE1L,KPNA2,RAB13,RPL3,SLC16A1,PALM2AKAP2,ATP2B4,SLC38A1,CKB,LAMTOR1,PSMD1,RALGAPA2,SLC1A3,STX16,EPS8,ESR2,RRAS2,FAM83B,CAV2,CSNK1A1,PAK2,SDC2,MAP2K1,IL6ST,USP6NL,GNB4,ITGAV,ABCC5,PACSIN3,BMPR1A,ARHGAP5,PPFIBP1,OLR1,YWHAG,XPO1,TENM3,CTNNB1,IQSEC1,RAB5C,WWP2,VAMP7,CORO1C,C2CD4C,TNIK,RAB35,ADCY3,HGS,PTRH2,TMEM59,PCDH19,ETFB,VAMP8,RAB8B,RAB18,SLC20A2,ROCK2,CDK5,EFNB1,GNA11,TMEM87A,TOP2B |
| 1.234e-07 | -15.91 | TRIM5 (tripartite motif containing 5) | protein interactions | 85363 | 90 | 49 | 19454 | 5460 |
TRIM35,UBE2N,RB1CC1,USP15,UBE2D1,PSMD7,XPO1,API5,TRIM34,USP2,MNAT1,TRIM21,EWSR1,TFPT,MAP3K11,TAB2,UBE2V1,TRIM6,UBB,UBE2V2,OTUD6A,USP5,YES1,LGALS3,PSMC5,SGTA,CREB1,UBE2H,LGALS8,RUNX1,NTAQ1,PCBD1,TRIM32,TNFAIP3,NFYA,CUL3,COIL,PIAS1,UBE2K,UBE2D3,PHB2,TRIM5,SQSTM1,USP39,CFTR,PSMC4,UBE2W,EHHADH,SUMO1 |
| 1.235e-07 | -15.91 | FGF11 (fibroblast growth factor 11) | protein interactions | 2256 | 168 | 79 | 19454 | 5460 |
LMNA,EIF4B,RPL27A,PPP1CB,RPL4,EIF5B,CXXC1,SKP1,MRPS7,PSMC1,SPECC1L,UGDH,RPL27,HADHA,DCAF16,PSMD14,CCT2,HSP90AA1,HNRNPAB,STAC3,MAT2A,MYC,NONO,PROX1,MATR3,RANBP6,TXN,RPL19,ERH,RPL22,PSMB6,CBX5,PSMA6,TUBA1B,SF3B4,SNRPD1,PSMC5,MRPL49,TBC1D4,PSMC3,RPL18,GPBP1L1,CCT5,STRBP,THAP1,RPS7,RPAP2,SERPINA3,SRPRB,HUWE1,PSMA5,AHCYL1,HNRNPA2B1,MYO1B,RPL3,SMCHD1,NOS1AP,DCAF5,DICER1,MAP4,HNRNPD,PRDX1,MOV10,PRPF19,PSMD3,TPM3,HNRNPA1,CCAR2,TCP1,SNRPD3,MRPL50,HSP90AB1,DHX15,MDM2,PSMB5,AIFM1,RPL9,PSMB1,LDLR |
| 1.245e-07 | -15.90 | RBM4 (RNA binding motif protein 4) | protein interactions | 5936 | 297 | 125 | 19454 | 5460 |
PRPF31,ZNF668,CUL2,CUL3,MYC,NSA2,MIR363,MIRLET7B,SF3B4,DLST,MIRLET7D,MATR3,DDX5,EP300,MIR106A,STAU1,HSCB,XPO1,MIR29C,VPS26A,MIR143,MIR221,MIR1-1,POU5F1,HNRNPD,DDX1,PEDS1,MIR31,MIR141,MIR214,HP1BP3,EED,MIR7-2,NUP35,EGLN3,PPIA,MIR9-1,HNRNPL,EEF2,TULP3,MIR222,SOX2,PDHA1,MIR206,MIR9-2,PABPC1,PAX6,MIR155,HNRNPF,RPL26,RPL7A,RPF2,RBM7,UBE2H,NRP1,MIR145,PTEN,PRKRA,POP7,SMAD5,SRPK2,RPP25,RPP25L,MIR1-2,MIR34B,MIR7-1,UTP15,MIR21,RPLP0,RPL26L1,HNRNPH3,HEXIM1,ZCCHC17,RPA2,RNF113A,MIR34C,MIRLET7I,HNRNPH2,NLE1,MIR205,RBM23,BAP1,MIR10B,RPA3,PPM1G,BRIX1,MIR29A,UTP23,RBM22,MIR7-3,WDR3,COPS5,GRSF1,MIR34A,SNRNP70,PWP2,MIR25,RPL32,MIR106B,SURF6,MRPL24,CDC5L,RBM42,DKC1,MIR429,MIRLET7G,CAND1,RPL15,MIR200C,ESS2,EEF1A1,KBTBD4,FURIN,NUPR1,RBM34,CDK8,MIR20A,MIR17,DHX9,MIR9-3,MIR200A,MIR16-2,MIRLET7C,HNRNPK,PAK1IP1 |
| 1.255e-07 | -15.89 | COX7C (cytochrome c oxidase subunit 7C) | protein interactions | 1350 | 95 | 51 | 19454 | 5460 |
TOMM22,UQCRC1,COX6C,ATP5PO,VAPB,HSP90B1,CYC1,PGK1,HADHA,PMAIP1,PDHB,NDUFS2,PHB2,SLC25A51,COX6B1,NDUFB10,TOMM40,NRP1,RIT1,UBE2H,UQCRC2,VDAC2,PSMA6,SEC61B,MGST3,ATP5F1B,ACTB,UQCRQ,ATP5PB,MTCH2,SKA3,PDHA1,NDUFS3,SLC25A24,NDUFB5,NDUFA4,COX8A,VDAC1,COX7B,CIDEB,CALR,COX5A,TMBIM6,AGR2,COX4I1,PHB1,CORO1C,CYB5A,MYL12A,ATP5PD,NDUFS8 |
| 1.265e-07 | -15.88 | MRPS9 (mitochondrial ribosomal protein S9) | protein interactions | 64965 | 370 | 150 | 19454 | 5460 |
GATD3,FBXO32,SRSF1,RMND1,HNRNPA1,TRA2A,DDRGK1,MTRF1,MRPS35,RPL6,MRPS26,ARMC8,RHOG,SKIC8,MRPL18,HECTD3,EWSR1,HINT2,MRPS11,SRSF7,COX8A,HSPD1,RBM3,MRPS17,IMMP2L,HNRNPDL,KRAS,NUP42,SOX2,TULP3,RPL18,PDHA1,RPS9,MRPL13,FAU,TACO1,MTG1,CCDC90B,RPL10,ESR2,RPL19,PRRC2A,MRPL23,RPL35,LAMTOR3,SNRPB,MTG2,MYC,AUH,HNRNPC,PSMA4,PMPCA,CUL3,NSA2,MCAT,NOA1,FBXW11,MRPS25,SNRPA,NGRN,EXD2,MRPS7,HSCB,UFL1,NOP53,STAU1,MRPL12,TIMM29,RPL27A,PABPC5,FGF17,PRR3,TRMT10B,PSMB1,SRP14,SSBP1,ALYREF,RCHY1,COX4I1,RBM42,SURF6,MRPS23,SLC25A12,FZR1,CAND1,MRPL50,CGAS,E4F1,GRSF1,DNAJC4,NOL12,SNRNP70,CHCHD1,TMEM70,CLPB,RPL3,MRPS18B,EMC2,FASTKD5,MRPS18C,MEPCE,RPL17,MRPS33,PSMA5,H3C1,DNAJC30,APOBEC3D,AURKAIP1,METTL15,STRBP,MRPL11,TP53,GFM2,STARD13,MRPS28,PTEN,BCCIP,MRPS21,ATP5F1A,AR,TUFM,CSK,PSMB2,NAPA,IGF2BP1,DNAJC19,UBE2H,MRPS16,RC3H2,SQSTM1,GFM1,RPA3,CRYZ,MRPL40,FBXW7,SLC25A51,RPL4,MRPL41,KLF12,RBMS2,ATG16L1,ZNF574,RPL26L1,HEXIM1,MTRES1,KLF4,ACACA,MRPS34,RPA2,FGFR1 |
| 1.271e-07 | -15.88 | ACAT1 (acetyl-CoA acetyltransferase 1) | protein interactions | 38 | 212 | 95 | 19454 | 5460 |
MRPS26,HSPB1,AK2,RHOG,AGR2,DDRGK1,MTRF1,CRIP1,PRDX1,NUP35,GATD3,PDHA1,TOMM7,SOX2,RAF1,UBE2A,RAD21,FLOT1,EWSR1,HINT2,COX8A,HSPD1,RHOB,AK3,MTG2,AUH,MYC,ACO2,CUL3,PMPCA,ESR2,TUBB,TAX1BP1,TENT5C,TACO1,CCDC90B,DLST,SIGMAR1,ACAA2,PAFAH1B1,EIF1B,UFL1,STAU1,HDAC5,COX17,HSPA8,PDSS2,EXD2,TOPBP1,TMEM70,COPS5,ATP1B1,GRSF1,ILVBL,SDHB,SSBP1,CD274,AIFM1,AURKAIP1,EEF1A1,METTL15,UBL4A,MRPL11,FASTKD5,PSMB10,MEPCE,HSPE1,CSE1L,ABCE1,HSD17B10,SFXN1,ATP1B3,SPOP,CFL1,TUFM,UQCRQ,DYRK1A,VIRMA,ACAT1,PTEN,STUB1,CCNF,UBE2M,MTRES1,RPA2,IDH2,ATG16L1,AKR7A2,CRYZ,MARS1,FBXW7,GFM1,RPA3,SOD1,SIRT7 |
| 1.290e-07 | -15.86 | cellular component biogenesis | biological process | GO:0044085 | 2716 | 915 | 18204 | 5365 |
ACTB,PNO1,HAUS2,SHMT1,NGRN,CX3CL1,CAPZA1,SF3B1,NDUFAF2,TEX12,TESPA1,TRAPPC14,MID1IP1,OIP5,PDIA3,RUVBL1,SLAIN2,CSRP1,RANGRF,RSL24D1,PFDN5,HFE,CLDN4,CXCL12,PHACTR1,CDK5,NSFL1C,MED11,EMILIN1,MOBP,FITM1,MYO1B,IL1RAP,MZB1,GTF2A2,RIOX2,MED4,LSM14A,LSM3,RBM5,TSPYL4,TMEM107,CASP4,RPL6,EID2,PRPF18,BOLA1,TRAPPC6A,TAFAZZIN,TNFAIP1,CD2BP2,SDHAF1,WDR44,LRRC8D,RP2,GJA1,COA4,H2AB1,NLRP3,KCTD9,SNRPD1,TPPP3,CNTN1,BOLA3,ARF6,CLDN3,ALDH1A3,TIFA,H1-5,AIF1,CSNK2B,CTSD,DDX23,SDCBP,KCTD12,MDM2,CIAO1,STK4,VCPIP1,SLC7A9,TP53,KIF3B,TUBG1,OCEL1,SOD2,NEK7,EHD1,RPL35,GABRA1,GEMIN7,ZNHIT3,EMG1,CIAO3,LARGE1,RAP2C,HOMER1,RBMX2,PIP4P1,ARF4,DLG4,USP39,IMP3,RPS15,CDC123,DET1,GABRA2,SAMM50,GPM6A,CEP70,SDHAF4,GABARAPL1,B2M,ATAT1,CFAP91,DROSHA,TLCD2,CD3G,PPP2R1A,DDX46,MAPRE1,SUV39H1,CHMP5,COA5,CHMP4C,CD247,GTF2B,GJB2,ADD1,GJB1,RAB29,GABRG2,LTO1,LSM2,FBLN5,GAS8,COL3A1,CHRAC1,DHX9,VAMP8,RAB1B,NAPG,PKP4,SF3A1,MAT2A,C9orf72,SLC31A1,CFAP20,ADRB2,ZNHIT6,NHP2,BUD23,PRPF19,CFAP61,ACTL9,HGS,VIPAS39,RABL2B,WDR11,NSA2,VTA1,EXOSC4,RPL7,GHRL,BAG3,SART3,SOX9,IMP4,SPATA6,BECN1,TRAPPC3,NAPA,FMOD,LRRC8C,CBLN1,DICER1,BANF1,RAB13,DLG1,UBXN10,SF3B5,ADD2,SPEF1,KCNC1,KCNB1,IL2RB,DDX42,RPS14,PELP1,IFT172,CLDN22,FERMT2,PSMG4,FLCN,CDC42,CRYAB,LIMD2,AGO1,NUPR1,NDUFS8,MIF,SHPRH,BCL10,MAP1LC3B,TLCD1,RFX4,TSSC4,NDUFB7,UNC119B,HEY2,ATP6V1D,C1QL2,SRSF12,STK3,THG1L,CLDN24,H1-10,SWAP70,RPS9,SEPTIN7,RUVBL2,AP2M1,SURF6,OPHN1,IFT22,H2BC9,NPTN,NDUFC2,CBLN2,FXN,RPL10L,SPTBN1,RS1,SLC2A1,UBAP1,KCTD10,XPO1,WEE2,TRMT112,TRIM32,VMP1,GLUL,ASIC1,TMOD3,MED9,RAB33A,TMA16,MED23,MRM2,RAB33B,MAK16,GK2,NLRP1,MED10,RAB14,CD40,NOC4L,KCTD3,POLDIP2,HDAC6,HSCB,NOL7,MED22,MALSU1,NHERF1,GLRX5,CLXN,GCFC2,MRTO4,NUP62,EIF5B,ARL6,EHD3,TUBB,CBLN4,ATP5F1D,LRRC61,SPMIP6,PIH1D1,DRD1,TMEM231,CCDC42,SNAP23,C1D,RPS13,TLR2,FKBP4,PRPF31,TACO1,TBCEL,CENPP,NTN4,FAM161A,PIAS1,VAMP3,RPL7L1,XRCC5,NPTX1,ACOT13,TCAP,NLE1,IFT52,PAFAH1B1,WDR12,TIAM1,TAF10,NDUFS2,NDUFAF3,COX20,FIG4,TNNT2,NUP107,NLGN1,P2RY12,ROCK1,CENPW,SERINC1,ADRM1,GNPAT,WDR55,H1-3,NDE1,NDUFAF6,RB1CC1,NDUFB10,H2BC17,POMP,UQCC2,WRAP53,UTP25,RPL35A,THY1,COX14,NECTIN2,TRAPPC2L,HSD17B8,PMP22,HIGD2A,TMEM170A,RPS12,NDUFB4,RPS11,EIF3E,AP2S1,ARHGEF6,RRM1,CEP85,CAPZA2,SAMHD1,RAN,WDR19,CLDN12,SSRP1,CUL3,KCND3,BSCL2,TERB2,YWHAZ,PRKACB,NDUFAF4,TIMM21,COX16,TCP1,STX17,GORASP2,NDUFB8,PCDHB13,DKC1,CIBAR1,CALR,NSG1,NUDCD3,RBBP4,MAP1B,TAPBPL,FAM107A,WNT7A,CLP1,ITGB5,KCND2,AIFM1,RPS4X,CFAP73,METTL15,EXOSC8,PRND,B9D1,RPL26,FKRP,ITGA2,GPC1,PIP5K1A,TFG,KCNS1,TAF11,TSG101,PLA2G5,FTSJ3,RPGRIP1L,NRP1,SRFBP1,CCDC69,KRT8,ATF1,LCP1,NUBP2,RPL27,FAS,ANP32B,FLRT3,KIT,PSMG2,HIRA,HIGD1C,PAK2,AR,REEP4,KIF2A,RAB23,IMMP2L,MACIR,G3BP2,BBS5,POP5,GPM6B,UBE2K,DDX1,TP53INP1,UTP6,HAPLN2,ASPM,CEP19,CETN2,DDX39B,NOP58,CHMP1A,ATXN10,SCLT1,RCL1,PRNP,SNAP29,E2F4,CLIP3,SF3B4,SLX1A,FAM149B1,SMN1,CCDC65,SSBP3,SMYD3,TPPP2,SAR1B,CRYZ,RPL7A,RBIS,TAPBP,CHMP2B,OTUD6B,EXOSC1,MNS1,TP53INP2,MED27,GTF2A1,ATG7,HDAC3,FHOD3,RPL10,NACC2,SLC39A9,OCRL,EHD4,AQP11,UBE2S,TNIK,LPCAT3,RBM34,ATPAF2,RAF1,TRAF1,TRAF2,ATL1,CNTNAP1,H1-1,TRIM6,RAB11A,RPS3,CINP,GABRB3,YTHDF1,MAPRE2,ZDHHC8,KCTD11,VPS28,EMC6,NTNG2,H2BC1,BCCIP,PREB,S100A10,PYCARD,BRIX1,STXBP6,KCNA3,VAMP2,DNAL1,INPPL1,PSMD10,RPF2,ZNF593,HSP90B1,PPAN,ZNF622,ATG3,CIDEB,USP16,ASIC2,PSMG3,H2AX,TFB1M,CTTN,NEFL,PRKCA,RPS16,H1-6,LDB1,PPIH,EXOC5,BOLA2B,RPS28,CDH11,TMEM126A,SRPRB,LPAR1,TAF7,BCS1L,NOP9,MITF,ITGA6,COX10,VPS4A,ATG101,FGFR1,SRSF1,NDUFAB1,TBCE,RAC2,CHMP1B,RRP7A,EMP3,POLR1B,UGDH,DNAAF10,POLE3,LRRC8A,FKBP10,LSM6,SRP54,CHCHD4,CNOT7,MKKS,YTHDF2,H2BC14,RPS5,COA1,CEP41,CAPG,RAB32,GABARAPL2,LYRM2,TMOD1,RAP2A,CALHM3,STX12,JUP,TMEM237,RACGAP1,CLSTN3,PAK1IP1,SRPK2,REEP3,SNRPD3,STBD1,KLHL12,GTF2H5,TWNK,SHOC1,NCK1,CLDN9,RAP2B,TRIM37,NDUFA1,WASL,EIF2D,EIF3J,NPM3,VPS4B,FARSA,CDH13,TPPP,CREBBP,PROX1,WDCP,JCHAIN,WASF3,KCTD15,NCKAP1,HPS6,TTC8,CCT2,H2BC11,NLRP6,COIL,CAV2,MACROH2A1,TMOD2,PLS3,MAP1LC3A,WDR3,NAP1L5,COPS5,SNRPA1,SNRPE,RAP1B,METTL25B,UBN1,GPX4,NAP1L3,CIRBP,CFAP298,CCL21,CTNNA1,PICALM,NDUFA2,ZNF207,PEG10,FITM2,G3BP1,RPL23A,CDC20,SLU7,TDRD7,KCNJ2,CLDN6,INPP5K,CDK1,SNIP1,SSBP1,EIF2S2,NDUFA12,HSP90AA1,MED21,WDR45,UQCC6,PWP2,SNAP25,ADGRL3,ACHE,CFAP161,PFDN6,CAV1,MCOLN1,ARPC2,TNKS,FCF1,NAA60,ZYX,RAB1A,TMEM70,HSP90AB1,MSRB1,CNTROB,KCTD17,CAV3,IFIH1,GABRB2,MPHOSPH6,IFT57,TAF2,ALKBH5,SNRPG,UBE2I,WBP11,CLDN1,YBEY,RPS27L,ATG9A,GJC1,PSEN1,MTM1,CDH8,ATG4A,ATG16L1,CDH7,EIF1AX,KCNJ10,CRTC2,ISCU,GPAA1,COL1A2,TAF9,ESAM,EIF4A3,RAP1A,RILPL2,CLTRN,COX19,KCNG3,CLU,TMIGD1,MACROH2A2,MED30,FCHO2,RPS7,NDUFA5,PSPC1,DISC1,SNRPD2,PML,CBR4,CFAP97D1,SRPRA,EIF2S1,NDUFB5,KCNJ8,SSNA1,UBXN2B,KCTD16,ALOX5AP,FGF13,CD2AP,NEK2,TSR3,PLN,TRAF6,NLGN2,HP1BP3,UTP23,TXNL4A,RAB19,SYCE3,NINJ1,BIRC5,DYNLL1,SNX10,MED17,TESK2,RAB8B,PDCL,MEF2A,PRKRA,TOM1,EXT1,PTGES3,MTMR2,CALY,SRC,SLC25A46,ANGPT1,C1QL3,SMARCA5,PPID,CLDN14,ISCA2,TM9SF4,KRIT1,EPS8,SNRPB,SQSTM1,SF3B6,COX17,MPV17L2,MECP2,SMARCB1,NDC80,NOB1,SLITRK1,SIGMAR1,TMEM199,TRAPPC4,EDC3,LPXN,CELF6,EXOSC3,CLDN8,KRR1,ISG20L2,UTP15,RPS24,NOP16,PET117,AP3S2,EIF3K,ACTR2,NBN,RPP25,DR1,RPSA,GEMIN8,AP1M1,PDCD10,UQCC3,WDR77,EIF3D,CATIP,VAMP1,BOK,POP7,HSD17B10,RPF1,CTNNB1,SLC1A2,IFT25,COPS7B,CYFIP2,AIF1L,GMNN,NOP53,MIOS,LSM4,GABARAP,PRMT5,RSPH1,ISG20,SDHAF2,MIS12,MED31,PTEN,JAK2,STXBP1,STX7,CAND1,TSR2,EIF3G,ASF1A,FGD2,UGCG,BAD,ACACA,RAB27A,ABCE1,TUBA1A,SSX2IP,CD34,RIOK2,TMEM126B,ENKD1,AATF,GRIA1,NUP153,STK26,RRN3,RIC3,CRKL,ATG4C,KCNF1,STOML2,RPS17,RNASEL,LDB2,SNRPB2,LRRC4,NDUFB6,COPS7A,CFL2,RTKN,PCDH17,KCNA2,OTX2,HAS3,AP1S2,MRPS7,HSPD1,WSB1,PALS2,GNMT,LUC7L3,FLOT1,SNAP91,MAP4,TRAF7,LYAR,CHMP2A,CLDN11,RPS23,NOA1,KHDC4,MED29,MLH3,AQP2,VAV2,RPL26L1,MPHOSPH10,SRSF10,RPLP0,GJA10,H3C1,NDUFS3,DNM2,NOPCHAP1,SEPTIN6,FMC1,ILDR1,B9D2,SMURF1,RTN4,EMP2,NGDN,MYBL2,TIA1,UBE2B,AQP4,POC1B,MTG2,CD9,TRAPPC1,COX7A1 |
| 1.300e-07 | -15.86 | negative regulation of endothelial cell migration | biological process | GO:0010596 | 101 | 55 | 18204 | 5365 |
ATP2B4,MIR200C,MIR29C,MIR137,MIR204,MECP2,MIR16-1,MIR129-1,HDAC5,MEF2C,MIR424,MIR320A,MIR20A,MIR193A,GADD45A,MIR206,JUP,RGCC,MIR149,CXCL13,MIRLET7B,MIR212,PPARG,MIR221,MIR503,MIR497,CSNK2B,MIR21,MIR492,MIR146A,MIR133B,STC1,SPRED1,MIR188,MIR505,PDCD10,TNF,SVBP,MIR24-1,MIR101-1,MIR640,SYNJ2BP,MIR15A,VASH1,HMGB1,MIR205,MIR495,MIR132,MIR885,STARD13,MIR10A,KLF4,MIR152,MIR361,KRIT1 |
| 1.304e-07 | -15.85 | POLDIP2 (DNA polymerase delta interacting protein 2) | protein interactions | 26073 | 201 | 91 | 19454 | 5460 |
RMND1,LYRM2,GATD3,HDHD5,MRPS26,RHOG,CLPX,MTRF1,IMMP2L,CHCHD2,EPHA4,G3BP1,COX8A,HINT2,PCNA,NDUFA4,HSPD1,CPE,FAM136A,DHRS3,PDHA1,EZH2,SOX2,PPP2R1A,MAD2L2,PARL,ESR2,NDUFAF4,TAB1,ZMYM2,MTG1,CCDC90B,TACO1,LSM14B,HTRA2,PMPCA,MRM2,CUL3,FMC1,ACO2,AUH,MTG2,HSCB,NMRAL1,EXD2,NGRN,PIH1D1,MED23,DHRS4,AGTRAP,COQ10B,HDHD3,AIFM1,COQ8A,SSBP1,CHCHD1,HDAC6,GRSF1,MOV10,MPST,MEPCE,FASTKD5,DNAJC30,H3C1,RNF8,GFM2,NDUFS3,METTL15,AURKAIP1,TP53,MRPL11,CMPK1,PTPMT1,PTEN,UBE2H,RC3H2,DNAJC10,TUFM,ATP5F1A,FBXO7,POLDIP2,NME4,GFM1,POLD2,RPA3,MTRES1,GSTP1,RPA2,PAK5,SPR,COQ8B |
| 1.304e-07 | -15.85 | SUN2 (Sad1 and UNC84 domain containing 2) | protein interactions | 25777 | 201 | 91 | 19454 | 5460 |
CDK7,ST7,CDC42,TMEM106A,HECTD1,SSR1,LMNA,RPA2,DERL1,RNF113A,LGI1,RPA3,HSPA5,UGP2,FTSJ1,ST8SIA4,CSGALNACT2,ARL6IP6,UBE2H,RC3H2,PIP4K2C,ENDOD1,SDF2L1,RPS20,DNASE1L1,METAP2,GXYLT1,VIRMA,ACVR1C,RHOJ,COPE,NRM,CLEC2B,GBE1,DISC1,SFTPC,PIK3CA,GOLGA7B,BSCL2,HAPSTR1,LRP3,SCGB1D1,SLC25A46,RAC2,ELSPBP1,CAV1,TNFSF18,DNAJC1,SEC62,DHRS4,RND2,OTULINL,FKBP14,RAB5A,SKP1,TACR3,FBXL4,NOP53,HSCB,GGH,CAV3,FBXW11,LMNB1,SEC61B,ESR2,CBLN4,SOX2,JUN,DNAJC25,PI15,HGS,PLD3,NCR3,RPN1,EZH2,PDIA6,TMT1A,TMEM87A,ATP5F1D,ACADS,CFC1,RAB5C,IFI16,YWHAB,RHOG,WDR6,CD1A,SRSF10,RHOH,COPS7B,DNAJB9 |
| 1.312e-07 | -15.85 | PTMA (prothymosin alpha) | protein interactions | 5757 | 190 | 87 | 19454 | 5460 |
GSK3A,GTF2A1,MSN,TRIM24,CCNF,VDAC2,MIDEAS,ENO1,RAN,GMDS,ACTB,RPGRIP1L,TOMM40,CREBBP,CCNB1,CUL3,H1-1,CKB,HSPA8,PGK1,VIPR1,STK26,EP300,NUBP2,YAF2,PSMA3,DDX39B,INPPL1,SOD1,DVL2,MEF2A,ZDHHC17,HSPA5,SRSF2,EIF5B,NSFL1C,PHB2,CFTR,CCNA2,TOMM22,NUP62,PSRC1,HEXIM1,UBE2M,CDK1,ISOC1,DSTN,PSME2,KLHL7,SIN3A,CD274,SRP14,SYNCRIP,PPIA,CDK17,MIF,SUMO2,YWHAH,PPIB,HNRNPA1,DNTTIP1,CTNNB1,CALR,H2AC14,PDIA3,KPNA1,YWHAB,AGR2,TRIM21,PCNA,HNRNPA2B1,RPS27A,RIGI,ANP32B,KRAS,PSMA1,KPNA2,HSPE1,MARCKSL1,TBK1,ANP32A,CDK4,CAPN2,NUPR1,APTX,EZH2,CAPZA2 |
| 1.325e-07 | -15.84 | CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3) | protein interactions | 54927 | 243 | 106 | 19454 | 5460 |
APOO,MTCH2,FAM13B,FURIN,CARD19,CLPB,HAPSTR1,EFHC1,SFXN1,MDC1,PDE2A,DNAJC30,LAMP3,GPRASP2,SLC25A46,DNAJC4,SSX2IP,DNAJC7,TMEM70,ESYT1,TRAK2,RAC2,COX4I1,AIFM1,HRAS,PLGRKT,SLC25A12,DNAJC1,CFTR,FAXC,CDC42,HEXIM1,SAMM50,RNF113A,DLAT,SQSTM1,HSPA5,TOMM20,SLC25A51,DNAJC5,NTAQ1,DEPDC1B,EXOC5,RAB2A,UBE2H,CHCHD6,TRIM27,OPTN,TRAF1,VIRMA,SMURF1,RHOJ,MGST3,TOP3B,B3GNT2,CHMP4C,PDHA1,EZH2,NDUFA4,ENKD1,IMMP2L,VDAC1,G3BP1,KRAS,RAB5C,LAMP2,HSPB1,RHOG,PHB1,NUP35,COX14,RMND1,EGLN3,RHOH,SNRPD3,ADCK1,NUDT3,DUSP22,TIMM29,RND2,PPP1CB,MTX2,TOMM22,ATP5PO,AKAP1,ARMCX2,RNF11,PHB2,UFL1,CCDC85B,TOMM40,ACO2,MYC,ARMC7,HTRA2,RHOB,LMNB1,SEC61B,RMDN3,CCDC90B,DLST,LMBR1L,ESR2,PARL,TRIM29,MTM1 |
| 1.326e-07 | -15.84 | PARP1 (poly(ADP-ribose) polymerase 1) | protein interactions | 142 | 1260 | 435 | 19454 | 5460 |
GSTM3,AGR2,RFX5,CORO1C,MACROD1,HMG20A,FAM98A,MEAF6,PGR,LYAR,ISG15,SOX2,MSX2,KIF2A,MAX,SUPT5H,MTA2,ZRANB2,KDELR1,RUVBL2,TOP2B,HMGN4,MLF2,NSA2,DNAJB6,THOC6,POLR1B,CHTOP,FTSJ3,PHKB,GTF2F1,TRIM29,ZNF362,RPL27A,FBXO42,PIH1D1,RAB30,HDAC5,HSPA8,EP300,RFC4,SLU7,XRCC5,STAU1,COPS5,ZNF24,POLB,TUBG1,SMAD4,SYNCRIP,STT3A,CD274,TMPO,DKC1,CDC5L,SHPRH,H2AX,ZMYM4,ZMYM3,PREB,RRM1,SRFBP1,RNF8,PHC1,TFCP2,GPD2,RBM34,NECAP1,RPL3,TRAFD1,TCEA2,CAPZA1,RASL10B,H2BC9,MAT2A,RSPH1,SUB1,PKNOX1,EIF2S2,PSMA6,LIG3,ZNF330,PAFAH1B3,ROCK1,SRC,BUB3,SNRNP27,CFTR,SUMO1,UBE2M,HEXIM1,HECTD1,RPA2,CWF19L1,PRDX6,BANF1,HSPA5,PRPF19,RSBN1L,TST,PPP3CA,NQO1,KDM2A,GJA1,HP1BP3,DNM2,PHB1,CACYBP,NTMT1,CETN2,NOP58,SNX2,CCAR2,SAP30,FEN1,RNF126,NLRP2,EZH2,AKT2,MORC2,ATF3,MCM6,RFC2,ANP32B,RFC3,TRIM37,RHEB,RFC5,SAMHD1,RIOK2,MCM3,MCM4,HNF1B,CUL2,CUL3,SP1,LMNB1,UBE2S,PARP2,PELO,TNPO3,RPL19,AKR1C2,RPL35,RPL7L1,PRDX3,PPP1CB,TIMM29,NCALD,H1-5,MED23,APOBEC3C,RTKN,COIL,POLA2,GTF2E1,HDAC6,GLO1,CALR,NFKB1,EMC4,TLE1,TOPBP1,SLC2A1,MPHOSPH10,SEC23A,H2AZ1,HACD3,CTDSPL2,UBP1,RCHY1,EIF2B2,TOP1,MLLT6,MAP1LC3B,LBR,DDX39A,SERPINB9,MTA3,ILF2,NUDT16,HAPSTR1,HINT1,MRPL22,OLA1,MSH6,EIF3E,THRAP3,ATP5F1A,NONO,AR,USP14,GMPS,TXNIP,IVNS1ABP,TDP1,GSK3A,UBE2I,STUB1,SH3BP4,CYP4F12,ATG16L1,RPLP0,MACROH2A2,IFRD1,CDK1,LMNA,JUP,SQSTM1,PNO1,MBD3,AATF,DGCR8,SMC4,NUCKS1,HMGB1,DNTTIP1,DDRGK1,CTNNB1,DDX50,IFI16,BAZ1B,WWP2,H2BC17,ARHGAP5,NCK1,SIN3A,ANXA4,SWAP70,HNRNPL,ECHDC1,SUMO2,NUDCD3,H1-3,TRMT1L,SMARCB1,APTX,MOB3C,RPS23,H2BC1,EWSR1,PRPS1,PELI1,BTF3,CPSF2,SNRPB,BAG3,MYC,CREBBP,HNRNPAB,H1-1,SERPINH1,IRF2,PAPSS2,CMTR1,CBX5,LRIF1,NCKAP1,APEX1,RPL10,TAGLN2,MTF1,CSNK1A1,PPT1,DR1,SRSF2,TRA2B,UFL1,E4F1,KPNA1,H2AC4,SMCHD1,SSBP1,MBD5,SPPL3,FZR1,CAND1,ATP5PB,STRBP,RPSA,TP53,CAPN2,NUPR1,CBX3,SURF4,CDK8,CAPZA2,CLPB,ZNF451,MEPCE,MPST,LPCAT3,H3C1,NEDD8,ZNF365,CSE1L,SMARCA5,SLC25A1,CCNB1,EXOSC1,IGF2BP1,CDKN2AIP,UBE2H,MECP2,CHRAC1,MACROH2A1,PSPC1,CTSB,HPF1,DAPK1,MAFG,LEMD3,RNF146,PGK1,DERL1,DLAT,BAP1,RPL27,PML,METTL22,WDR3,HDAC3,BCL7C,HMGA1,ATG9A,RB1CC1,HNRNPD,PPM1B,MAP1LC3A,PSMB5,SRSF10,RPL29,PPP2R1A,JUN,NAA15,B3GNT2,RAF1,ARFGAP1,RPS11,GDI2,CHMP4C,HECTD3,PCNA,PRPSAP1,SCD5,RPS27A,GTF3C3,PSMD12,SACM1L,RAD21,SSRP1,ZBTB16,DHX16,PRPF31,SMARCE1,RPS29,NFYA,BRCA1,SNRPD2,ZMAT2,S100A6,VPS72,CD86,ERH,CLIC4,USP5,RANBP6,ACTB,LGALS3,TUBB,MED17,CDKN1A,ASRGL1,ACTL6A,MFAP1,KCTD12,LARP4B,ZFP64,EMG1,NKAPD1,NOP53,H2AC14,MOV10,CNN3,EMX2,BRD3,SPP1,ECD,MYBL2,LDLR,RB1,SMAD3,CDK9,MDM2,RPL35A,H2AJ,FBP1,TMEM126A,TOPORS,FAM169A,GPX7,ACTR2,FAF1,NKRF,H2AC6,HUWE1,VRK1,DNAJC8,RACGAP1,CDC73,AP2A1,SMAD2,CCNF,CTTN,CTNNA1,FERMT2,UBE2L3,VIRMA,NDN,CPT2,CCNA2,SF3A1,NFYB,PIP5K1A,HNRNPH3,METTL14,PICALM,KIN,RAB33B,HELLS,RPA3,PPM1G,PIAS1,BRIX1,NF2 |
| 1.326e-07 | -15.84 | SRC (SRC proto-oncogene, non-receptor tyrosine kinase) | protein interactions | 6714 | 624 | 234 | 19454 | 5460 |
DEFB116,SHC1,TPM3,CSNK2A1,KARS1,DPP4,TMPO,CYSTM1,GRM1,FZR1,CEBPG,LHFPL2,ITK,AIP,TSPAN3,WBP11,TMSB10,CENPM,TP53,UBL4A,PHF1,SCML1,HNRNPK,MRPS33,AKAP12,GALNT12,ABCE1,ATP2B4,KCNB1,ATP1A1,TLR9,CFL1,PTGER2,KCNQ5,PTPN11,TNFAIP3,SMARCA5,AKT1,RAB2A,SRC,BCCIP,SRPK2,TRAF1,NR1I2,PRKCE,STAT5A,GPX1,PRSS8,CSNK2B,STAT6,PRKCA,STX17,FGFR1,DDX4,CD46,RPA2,CD2AP,HSPA5,HDAC3,RAB9A,NR1I3,YWHAB,CBL,IKBKB,CTNNB1,YWHAG,YWHAH,LCN6,LAMP2,HSP90AB1,HNRNPL,PGR,POLR2L,FAM136A,ISG20,RND3,SMARCB1,CA14,SPG21,NCSTN,ERRFI1,FASLG,CBLL1,KRAS,GJB1,EPHA4,EFNB1,CDK5,PABPC1,S100B,CRMP1,LAMTOR1,BRMS1,HNRNPC,EPS8,COX6B1,CREBBP,EFNA5,RABIF,RPL10,ESR2,POLR2B,TOM1L1,MANSC1,STAT1,DLG4,NFKBIA,ZNF189,DOK4,CAV2,MAP2K1,PAK2,SDC2,CD59,SYK,MRPS7,ADRB2,HNRNPA0,EP300,HSPA8,TMEM220,FGR,TIAM1,PTGER4,MED21,PROM1,DAG1,LAMP3,CD36,CAV1,MDM2,POLR2I,ARF6,HRAS,PTPN1,ACBD7,ADRB3,POLR2G,DMAP1,IZUMO1,GPAM,SLC29A1,PSMB9,MAP1LC3B,TBK1,RIGI,CTNND1,FN3KRP,WASL,IGF1R,RNF133,TLR4,MAPRE1,AR,SKAP2,NONO,CNTNAP1,CSK,FERMT2,YES1,ABHD17A,CTTN,TUBA1B,ENO1,PELP1,STUB1,GAB1,AGAP1,MET,JUP,FBP2,CDK1,ARHGAP1,SPR,USP8,CERS2,GTF2I,MAVS,VIPR1,INPPL1,RPA3,CDKN1B,TRAF6,HNRNPA1,PIK3R1,ATG9A,TMEM170A,SPTAN1,TRIM15,CCAR2,AFAP1L2,CX3CL1,RPLP2,GJA1,PPP2CB,DNM2,DHRS3,POLR2D,POLR2C,IFNGR1,ACTN4,E2F4,RAF1,VDR,KIT,TRMO,PLSCR1,NLRP3,FHIT,HSP90AA1,RHOB,FAS,FYTTD1,SMARCE1,RAB11A,GRB10,DEFB114,PIK3R3,JAK2,TUBB,LAMTOR3,POLR2F,EDNRA,ANXA7,SLC25A3,FERRY3,OTULINL,KCND3,RNF11,STX7,CYFIP2,TERT,HADHA,TMEM185A |
| 1.346e-07 | -15.82 | TCEA1 (transcription elongation factor A1) | protein interactions | 6917 | 118 | 60 | 19454 | 5460 |
DSTYK,GTF2E2,TULP3,TP53,NAA16,ATP5PB,ARFGAP1,TRMT1L,POLR2C,POLR2G,CDK8,EZH2,MRPS11,TCEA2,DUSP19,RIGI,CSE1L,KRAS,G3BP1,SLC25A32,GTF2E1,SLC38A7,ERCC3,MED4,SKIC8,ANKRD49,G6PC3,EED,GTF2B,ZBTB2,CDK9,CDK7,SETD3,SF3A1,MED23,RPA2,DDX5,EP300,ELOF1,DDX46,BAP1,STAU1,MCM3,AR,SORD,DNAJB6,CDC73,CYP1A1,CHORDC1,GTF2F2,ZMAT2,GTF2F1,PTCRA,NFKBIA,BCCIP,EAF2,POLR2B,SNRNP40,MED17,LDHA |
| 1.350e-07 | -15.82 | IFITM3 (interferon induced transmembrane protein 3) | protein interactions | 10410 | 511 | 197 | 19454 | 5460 |
BANF1,ITM2B,LSM12,RAB9A,DLAT,AIF1L,PIP4P1,CLDND1,NTPCR,RPA2,SDCBP,BORCS5,UQCRC2,CDIPT,LIG3,PSMC5,SEC61A1,SLC1A1,ROCK1,SRC,LHFPL6,C9orf72,GORASP2,ST13,ATP1B3,SNX14,ATP1A1,CALU,ATP5PF,ABCE1,PSMA5,SRPRB,TMEM33,TGFBR2,ATP5PB,TP53,TFRC,SURF4,CAPZA2,NHERF1,PCMTD2,GNAI3,TRAPPC3,MIOS,ARL6IP5,TMED9,FUNDC2,TSPO,KARS1,DDX39B,XRCC5,FXR2,RER1,MTMR6,BORCS6,DIO3,CSNK1A1,VDAC2,RETREG3,PSMD4,ATP5F1B,ESR2,EPS8,RALGAPA2,UFD1,LAMTOR1,CRMP1,ZMPSTE24,CD83,MYO1B,ROCK2,VDAC1,POLDIP3,SNAPIN,PCDH19,HGS,CRKL,RAB35,MAGED2,CORO1C,SPINT2,TRAPPC10,RAB1B,EIF2S1,VAMP7,LANCL1,XPO1,FAM241A,FAM241B,DVL2,RPA3,SQSTM1,RTN4,YKT6,USP8,HMGB1,CHMP2B,RABL3,ARHGAP1,SLC35E1,CNP,PICALM,STAMBP,STUB1,PLP1,VAMP3,SMAP2,SNX12,MSN,TMOD3,SNX3,YES1,TECR,VIRMA,ATP5F1A,RACGAP1,ARFGAP3,NAPA,AP2A1,REEP6,TRAPPC1,STX8,TOM1,ARF4,PTGES3,VPS16,MRPL11,YTHDF2,ACTR2,ADAMTS1,VAC14,TRAPPC13,HACD3,EHBP1,CDCA3,SEC23A,CGAS,DERL2,ATP5PD,TRAPPC6B,CALR,ATP5MG,LAMTOR2,TRAPPC4,ATPAF2,TSPAN15,ATP5IF1,RABAC1,HADHA,SLC35F2,YTHDF1,STX7,RNF11,RRAGA,PGRMC1,LMO4,ATP5PO,MYL6,GNG12,FAM91A1,EDNRA,AP2M1,MB21D2,ACTB,REEP4,LAMTOR3,GPR37,CHCHD3,GNB1,BORCS7,CHP1,VEZT,FMC1,OPRM1,CUL2,MYO6,OSTM1,NDUFA4,JAK1,BAG2,ACTN4,FAF2,ERLIN2,RPN1,VAMP2,VPS33A,AQP3,STX12,TMEM14B,PLD3,ATP6V1A,SNX17,OCRL,SNX2,SPTAN1,TMEM208,RHOG |
| 1.350e-07 | -15.82 | p53-Dependent G1 DNA Damage Response | REACTOME pathways | R-HSA-69563 | 65 | 41 | 10285 | 3229 |
SEM1,PSMB9,PSMD7,PSME2,PSMD10,PSME1,PSMB4,PSMD6,RPS27A,UBA52,CCNA2,PSMD4,UBB,PCBP4,PSMD14,PSMC3,TP53,PSMA1,PSMB5,PSMA3,MDM2,PSMC4,COP1,PSMC1,CDKN1B,PSMD12,PSMB7,PSMD3,PSMB1,CDKN1A,PSMB2,PSMD1,PSMA2,PSMB6,PSMA6,PSMB3,PSMA4,PSMB10,PSMA5,PSMB11,PSMC5 |
| 1.350e-07 | -15.82 | p53-Dependent G1/S DNA damage checkpoint | REACTOME pathways | R-HSA-69580 | 65 | 41 | 10285 | 3229 |
PSMD10,PSME2,PSMD6,PSME1,PSMB4,PSMB9,SEM1,PSMD7,PSMC3,PSMD14,TP53,PSMA1,UBA52,RPS27A,PSMD4,PCBP4,UBB,CCNA2,PSMD3,PSMB7,CDKN1A,PSMB1,MDM2,PSMA3,PSMB5,CDKN1B,PSMD12,PSMC4,COP1,PSMC1,PSMA4,PSMB11,PSMC5,PSMA5,PSMB10,PSMD1,PSMB2,PSMA2,PSMB6,PSMB3,PSMA6 |
| 1.352e-07 | -15.82 | GPR35 (G protein-coupled receptor 35) | protein interactions | 2859 | 131 | 65 | 19454 | 5460 |
GOLGA5,SLC12A2,GHITM,GALNT1,FTH1,YIPF5,SLC19A2,SYNGR2,SLC37A4,CERS6,DAD1,ZDHHC17,MFSD3,CMTM6,CERS2,RNF5,RTN4,ATP5IF1,RAB29,ATP2C1,ATP1A1,ATP5MC1,ATP1A3,ATP5F1A,KDSR,TNPO3,YES1,LGALS3,ATP5F1B,SLC30A7,GNAO1,CH25H,KTI12,SCAMP2,CCL1,PLD3,KDELR1,SURF4,TMEM94,AGPAT5,YIPF3,SELENOK,ATP5PB,RIGI,SACM1L,VDAC1,APH1A,TSPAN7,GPR146,RUSF1,NSDHL,FITM2,FAM241B,SLC2A1,TMBIM6,CD81,ATP5MG,EI24,MSMO1,AIG1,ATP5PD,DERL2,VTI1B,STARD3NL,MCOLN1 |
| 1.361e-07 | -15.81 | negative regulation of translation | biological process | GO:0017148 | 206 | 96 | 18204 | 5365 |
MIR132,MIR26B,DAPK3,MIR939,ATF4,MIR590,MIR148B,ENC1,EPHA4,MIR133B,MIR106B,MIR15A,AGO1,MIR107,MIR135B,DAPK1,MIR126,MIR1-1,EIF4E,MIR379,MIR31,TIA1,MIR106A,TRIM3,SESN2,SYNCRIP,MIR148A,MIR100,BTG2,MIR208A,MIR146A,EIF4EBP3,MIR21,MIR96,MIR212,MIR503,MIR218-1,MIRLET7I,MIR204,EIF3E,MIR181C,MIR298,GAPDH,RNF139,MIR28,MIR874,MIR29A,IFRD2,MIR210,RGS2,MIR1271,MIR182,MIR495,MIR205,MALSU1,MIR98,MIR144,CALR,MIR24-1,MIR101-1,MIR346,SHMT1,MIR877,MIR9-1,RPS3,MIR345,INPP5E,MIR145,EIF4A3,TNRC6C,PAIP2B,EIF4E2,EIF2AK2,CIRBP,MRPL13,MIR214,CSNK2A1,MIR17,CPEB1,MIR20A,MIR181D,RPL13A,MIR378A,MIR221,PAIP2,MIR125A,EIF4EBP2,LSM14A,MIR29C,IGF2BP1,MIR200C,MIR10B,MIR448,TYMS,MIR16-1,EIF2S1 |
| 1.368e-07 | -15.80 | LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1) | protein interactions | 55004 | 714 | 263 | 19454 | 5460 |
NOS1AP,RAC2,ATP8A1,DSTN,ADD1,SLC39A10,FCHO2,VTI1B,STX6,SLC38A2,MTCH2,SNAP29,UBIAD1,CAPZA2,EXOC3,TFCP2,TFRC,SPRY1,SH3GLB1,SLC25A11,ATP2B4,PALM2AKAP2,SLC16A1,RAB3B,SLC6A8,RAB2A,NDUFAF2,C9orf72,DNAJC5,GORASP2,ST13,ENDOD1,AP3S2,SNX5,ATP1A1,NECTIN2,ALG2,CDIPT,STX10,SEC61A1,MRPS28,SRC,ROCK1,CAPN1,SPTBN1,CDC42,VIPAS39,BORCS5,RPA2,SDCBP,CSNK1G3,VPS54,BAP1,RAB9A,ARFIP1,FTSJ1,TUSC2,PIP4P1,SLC38A7,RAB5C,LAMP2,SLC38A9,PPFIBP1,FKBP4,DEGS1,IKBKB,AVL9,DRG1,TNIK,RAB35,FAM219B,STX5,RHOH,RAB1B,VAMP7,ARFGEF1,SPG21,NUDCD3,SNAPIN,KDELR1,RAB4A,NUDT19,HGS,RND3,TMEM87A,RTCB,EFNB1,RUVBL1,SLC20A2,ROCK2,KRAS,VAMP8,BAG3,SLC1A3,CKB,SLC38A1,CCDC90B,FAM83B,ATP5F1B,ESR2,ATP6AP2,TOMM22,MTMR6,USP6NL,TOM1L2,BORCS6,LMBRD2,TPD52L1,CSNK1A1,KLC2,TMEM106B,XRCC5,PEBP1,RAB5A,HSPA8,GOSR1,ABCC5,LAMTOR2,SLC25A46,KXD1,RELL1,RAB23,HDAC6,LAMP3,SLC2A1,OSBPL8,DNAJC7,EHBP1,HRAS,CDCA3,CGAS,ELAPOR2,ARF6,CAV1,EEF1A1,SLC29A1,CASK,DLG1,GARRE1,SFXN1,SLC25A10,RAB1A,STX8,EHD4,SNAP23,IGF1R,VRK1,FARSA,CTNND1,ARF4,PSEN1,DEPDC1B,ARFGAP3,AP2A1,EPHA2,STK11,SMAP2,CCNF,VAMP3,GAB1,STUB1,SNX12,YES1,RHOJ,SNX3,RAB14,ANKH,TECR,FERMT2,UBA52,PIP5K1A,ARHGAP1,PSMC4,ATG16L1,CNP,SYNRG,PICALM,GOLGA5,STOM,SLC12A2,JUP,CDK1,PTP4A2,BORCS8,RPA3,MME,RHOU,ITGA2,FLCN,PIK3R2,YKT6,CERS2,SLC7A1,ATG4C,BRIX1,CDC42EP4,ATG9A,UBXN6,PIK3R1,WDR11,RHOG,LRRC57,VPS4A,WDR6,ATP6V1A,CYB5A,GJA1,SNX1,SNX2,AGK,OCRL,CACYBP,RAF1,TPD52,PLEKHA8,PRKAG1,VPS33A,VAMP2,STX12,NUDT5,SCYL2,COX8A,BLOC1S2,ETFA,SEMA4C,RRAGB,FLOT1,PSMD12,PKP4,RAB11A,NIBAN2,TOMM40,MAP3K21,RHOB,WDR20,MYO6,NLRP3,FAM219A,CNIH4,ARF1,FAM91A1,SEC61B,AP2M1,LAMTOR3,RBBP4,MB21D2,BORCS7,NDUFAF4,NOTCH2,RRAGA,PRKAB1,DUSP22,RND2,EHD1,VPS18,MYL6,PRKD3,ATP2C1,CLDN1,TTC1,CCDC186,STX7,PSMC1 |
| 1.380e-07 | -15.80 | positive regulation of mononuclear cell proliferation | biological process | GO:0032946 | 146 | 73 | 18204 | 5365 |
PDCD1LG2,MIR30B,MIR21,CD81,CD46,CCR2,IL2,TGFBR2,AIF1,EFNB1,CCL19,TRAF6,MYD88,TACR1,PRKCQ,IL4,TLR9,CD38,MEF2C,IL7,CHRNB2,IL23A,CD28,CD80,TIRAP,CDKN1A,IL2RA,BCL2L1,IL5,IL15,TICAM1,EPO,JAK2,PYCARD,PELI1,AGER,CD40LG,LEP,TLR4,IL6ST,IL12A,FOXP3,CD274,BCL6,IL1B,CD40,DHPS,HMGB1,SASH3,CD1D,PPP3CA,IL18,PNP,MIF,CD86,NCK1,RPS3,SELENOK,IL13,TFRC,GPAM,FGF10,IL21,IL6,SLC39A10,IL1A,SLC7A1,XCL1,ST6GAL1,IL12B,IGF1,CD209,CCL5 |
| 1.392e-07 | -15.79 | VAV1 (vav guanine nucleotide exchange factor 1) | protein interactions | 7409 | 204 | 92 | 19454 | 5460 |
DNAJC1,CD28,LCP2,ACTA2,HACD3,HRAS,ALDH1A3,SHC1,TMOD2,HNRNPK,SRPRB,FARSA,TMEM33,PRDX4,ARF4,SLC25A11,PPP1R12A,SLC25A10,PALM2AKAP2,HAPSTR1,DDX39A,COPE,TECR,TUBA1B,GAB1,ZNF655,PHAX,RTRAF,SEC61A1,IVNS1ABP,ATP1A1,SLC25A1,AR,RACGAP1,TUFM,CFL1,ATP5F1A,SMC4,LIN7C,PTPN22,FGFR1,TMOD1,MET,ATG16L1,CFTR,CDC42,PRKCQ,DNM2,EED,RHOG,HSPB1,RPL23,CBL,PIK3R1,SIAH2,XPO1,PPIB,RUVBL1,VDAC1,PRPS1,FLOT1,SRSF4,S100B,SLC25A5,ZYX,PRPSAP1,BLOC1S2,TUBB4B,EZH2,SF3B5,RAF1,TUBA1A,JUN,SIAH1,TUBB,CHP1,JAK2,SERPINH1,LDHB,MRPL57,CDSN,ATP5MK,XRCC5,SPECC1L,CXCR4,MAP2K1,ATP5PO,SLC25A3,TOMM22,SYK,MRPL12,IL6ST |
| 1.398e-07 | -15.78 | UNC93B1 (unc-93 homolog B1, TLR signaling regulator) | protein interactions | 81622 | 412 | 164 | 19454 | 5460 |
PHB1,ATP6V1A,XPO5,TCP1,SNRPD3,TMEM237,OS9,NDUFS8,ERLIN1,STOML2,FATE1,EXOC1,XPO1,HAX1,VPS4A,RINT1,PCNA,ATP5F1D,ETFA,VDAC1,SACM1L,RAB18,RAF1,DCAKD,MACO1,TNPO2,ERLIN2,YIPF3,TUBA1A,AQP3,PTRH2,RPN1,PLD3,SNRPE,PIGK,CYB5R3,RAN,VDAC2,GPR173,GPR89A,SLC30A7,SNRPD2,SNRPD1,EDNRA,ATP5F1B,CHP1,ESR2,NDUFAF4,B4GAT1,TNPO3,POLR2B,GGH,SAMHD1,CKB,DNAJB6,SCFD1,TSPAN15,CXCR4,ATP5IF1,ATP5F1E,ATAD1,EEF1G,PHB2,GOSR1,UFL1,EMC1,NDUFS2,PGRMC1,NUP62,YIPF5,PRDX3,SEC62,SYNDIG1,VAPB,ATP5PO,LMBRD2,SLC25A3,ARCN1,FDFT1,UBE2G2,COX4I1,SSMEM1,PTPN1,AIFM1,COQ8A,STT3A,HACD3,DERL2,EIF2B5,GNPTG,COG1,TMED9,DNAJC1,CAND1,ILVBL,ATP5PD,ATP5MG,COX5A,EI24,ATP1B1,HM13,TM4SF18,TUBG1,P2RY1,OSBPL8,DNAJC7,UPK1A,ATP5PF,GARRE1,TMX3,EMC2,CLPB,FARSA,CSE1L,GPR37L1,RNF115,ERLEC1,MSH6,SLC6A8,SMIM11,FASTKD5,IPO8,CCDC47,ATP5PB,TFRC,SURF4,TLR3,SEMA7A,PSMC3,SELENOF,SCAMP2,TLR8,CDIPT,SYNGR1,CTSB,COPE,SEC63,TECR,CIAO1,NDUFB10,HMOX2,CNNM4,ATP5F1A,EXOC5,TLR9,DNAJC10,ATP1B3,ATP1A1,XPOT,MAIP1,VIPR1,SMC4,CERS2,MARS1,TMEM209,SEC22B,COQ8B,RABL3,CFTR,ST7,TRAM1,SLC35E1,EIF2B3,TTI2 |
| 1.402e-07 | -15.78 | TRUB2 (TruB pseudouridine synthase family member 2) | protein interactions | 26995 | 347 | 142 | 19454 | 5460 |
FAHD1,PHB1,PNPLA8,NDUFS8,SRSF10,HNRNPL,PAIP1,TRA2A,HNRNPA1,NDUFV2,MRPL9,STOML2,MRPS35,CLPX,MTRF1,LAMP2,MRPS26,RHOG,MRPL18,MRPS11,SRSF7,HINT2,HNRNPA2B1,UQCC2,PREPL,RPL31,HSPD1,HNRNPDL,MRPS17,ETFA,NUP42,ATP5F1D,KGD4,KRAS,ETFB,HSDL2,RAF1,NDUFA12,PDHA1,NDUFS6,NUDT19,MRPL13,DLST,TACO1,NDUFAF4,MRPL23,ATP5F1B,MRPL16,PMPCA,HNRNPAB,PYCR1,AUH,H1-1,MCAT,BOLA1,NOA1,FBXW11,MRPS25,HADHA,ATP5F1E,NGRN,MRPS7,PHB2,MRPL57,TRA2B,NDUFS2,MRPL12,NDUFAF3,PABPC5,NDUFA5,RNF7,ATP5PO,MRPS18A,PRR3,COX4I1,SDHB,SSBP1,MRPS9,MRPL24,MRPS23,MALSU1,RBM42,ATP5PD,DBT,MRPL50,ATP5MG,COX5A,MICB,GRSF1,RPS2,SNRNP70,HSD17B10,CLPB,MRPS18B,ATP5PF,MRPL52,MRPL22,FASTKD5,MRPS18C,HNRNPK,HSPE1,MRPS33,BCS1L,METTL15,APOBEC3D,HADH,PPIF,DUSP1,DDX39A,MRPL11,NDUFA2,MRPL47,ATP5PB,MRPL51,MRPL49,ILF2,NDUFS3,ACAT1,MRPS28,EIF2AK2,MRPL53,MRPS21,PYCR2,NDUFAF2,MRPS16,GFM1,DLAT,TWNK,MRPL20,POLDIP2,UTP23,MRPL40,MRPL41,NME4,MRPL17,PDHB,FTH1,RBMS2,MRPL10,MTRES1,QRSL1,MRPS34 |
| 1.408e-07 | -15.78 | STX18 (syntaxin 18) | protein interactions | 53407 | 139 | 68 | 19454 | 5460 |
PXMP2,STX7,HSCB,GOSR1,NAPG,BET1L,RAB9A,DERL1,RPA3,DVL2,CHRNB2,USE1,SSR1,FGFR1,OTULINL,CNPY3,SEC62,ST7,PGRMC1,BET1,FUT8,SEC22B,TECR,SEC61B,STX10,VAMP3,S100A6,LMBR1L,SCFD1,NAPA,RIT1,RACGAP1,STX16,VAMP5,VAMP8,FKBP8,KRAS,SRPRB,SNAP23,STX8,CYP2C9,RINT1,TMT1A,STX12,NUPR1,STIM1,RPN1,IFT57,DISC1,DNAJC25,SNAP29,CCDC47,TP53,CHRM3,VAMP7,STX6,EGLN3,TMPO,RTL6,DNAJC1,VTI1B,HSD17B11,RAC2,STX5,PTPN1,RHOG,ESYT1,FAM20C |
| 1.408e-07 | -15.78 | ERG28 (ergosterol biosynthesis 28 homolog) | protein interactions | 11161 | 139 | 68 | 19454 | 5460 |
MGST3,NR1H2,REEP4,DYNLL1,CREB1,PAFAH1B3,ELOVL4,ENO1,RETREG3,FAS,CYB561,MFSD14B,CREB3,TM4SF19,SCN3B,SNRPB,TTR,HMGB1,JAGN1,PHYHIP,COX17,HSPA8,SAT1,CCDC106,ZFP64,LMNA,STOM,LSM2,HNRNPH3,CCL18,ANXA7,PPP1R8,TMEM106A,CDC42,POLR3F,PIGY,MSMO1,TLCD4,SSMEM1,S100A8,HSD17B11,CLN8,LDLR,NCR3LG1,STX1A,PDZK1IP1,AQP2,MPHOSPH6,MOV10,ZNF24,FAM174A,FCGR2B,CRADD,HSPE1,GPR37L1,TFG,NAT9,SNRPG,SEPHS1,NSDHL,GADD45A,PQBP1,ERG28,RAB27A,TMEM31,AQP3,POLR2C,SERPINB9 |
| 1.411e-07 | -15.77 | SRPK2 (SRSF protein kinase 2) | protein interactions | 6733 | 708 | 261 | 19454 | 5460 |
GTF2E1,GRSF1,MOV10,ERCC3,BRD3,KRR1,ZBTB2,AKAP17A,NCBP2,CDK9,TOP1,RPL15,EXOSC8,LBR,DDX39A,MAP2K3,TAF1D,SRP72,CASK,ALPL,VAC14,LLPH,RPL23A,TCOF1,NKRF,MDC1,VRK1,THRAP3,NSG1,CTNNBL1,DNAJC8,GGCX,MAPRE1,PPIG,GSK3A,PRKRA,EIF4A3,TUBA1B,CCNF,PELP1,VIRMA,RPL22,RPL13A,LDHA,TXN,CDK7,MYLIP,ATG16L1,MACROH2A2,RPLP0,RPL26L1,CARHSP1,ZCCHC17,LMNA,SQSTM1,H2BC12,CLK1,PRPF4,PPM1G,RPA3,UTP23,AATF,GABARAP,CDC42EP4,BRIX1,RPL4,FBXW7,DGCR8,TRA2A,HNRNPA1,MAP1S,HMGA1,DROSHA,WDR12,DDX23,ELP6,HP1BP3,RPLP2,MRTO4,DHX15,PPIA,SRSF10,ZNF593,TNFAIP8L2,MAK16,GABARAPL1,TPD52,RAF1,MACO1,SNRPE,SRSF8,SRSF7,FAM76B,PPAN,ARGLU1,AHCYL1,AP1M1,SRSF4,ZNF592,MCM4,RBM15B,ZNF668,CUL3,NOP16,RIT1,LMNB1,OCEL1,FAM43A,SNRPD1,RSRC1,PRRC2A,BTG3,ACTB,ATAT1,ALKBH3,MAPKAPK5,MFAP1,VAV2,APOBEC3C,USP39,NUP50,CCDC86,PSMA3,UPF3B,COIL,NOP53,SRI,MZT2B,COMMD5,RBM17,SELENOS,RIT2,TCEANC2,RPL10A,MAP4,MAGEB1,CDK12,SMCHD1,SNRNP70,ADPRH,NXT2,POLB,RPL32,SLAIN2,SURF6,CDC5L,DKC1,TMPO,NKAP,RPS16,CAND1,ZMYM4,TMSB10,WBP11,ARHGAP12,CCM2,RBM34,DNAJC2,LRRN4CL,RPL3,MRPS18B,SNIP1,RPL17,SRSF12,FGF12,TOLLIP,HNRNPK,RPL7A,AKT1,RPF2,SLC25A1,UBE2H,PHAX,FGFBP1,RBMX2,ZNF330,PSPC1,SRPK2,SRC,DYRK1A,EGLN2,SNRNP27,GTF3C4,HECTD1,LUC7L3,DYRK2,TFIP11,ZNF326,PTPN22,RNF113A,HNRNPH2,TWNK,MAPKAPK3,RBM23,DDX46,BAP1,CLU,DDRGK1,NGDN,WWP2,UBE2E2,PTDSS1,DDX50,YWHAB,MAGOH,DRG1,EED,HOMER3,SRSF1,LYAR,HNRNPL,RPS10,CBLN4,SOX2,VSTM2L,GHR,ZRANB2,SDR42E1,MYO1B,PABPC1,TOP2B,RPL31,POLDIP3,RPL28,CCAR1,KRAS,GXYLT2,PELI1,BAG3,DRAP1,SNRPB,BTF3,HNRNPC,NSA2,H1-1,RPS26,FTSJ3,RBM27,CHTOP,SRXN1,ESR2,APEX1,CBX5,SNRNP40,MATR3,CAVIN2,NEK7,EIF4B,EP300,DDX5,GNGT2,HERC3,XRCC5,LCA5,DDX39B,SNRPA,STAU1,UFL1,TRA2B,SRSF2,FXR2 |
| 1.419e-07 | -15.77 | UBE2D3 (ubiquitin conjugating enzyme E2 D3) | protein interactions | 7323 | 266 | 114 | 19454 | 5460 |
RNF41,RNF11,STAU1,UBE2D3,RNF5,IL1B,RMND5B,TERT,RNF10,RLIM,PCGF2,SAT1,BIRC2,TRIM5,PIH1D1,RNF7,KLHL3,PTAR1,UBTD1,SIAH1,HECW1,SMU1,UBE2S,NFKBIA,COP1,FBXW11,BRCA1,CUL2,PCGF6,MSL2,RNF26,TRIM37,XPNPEP1,PELI1,PCGF3,TRIM26,UFM1,TRIM11,UBE3A,TRIM21,HECTD3,PCNA,MAEA,RNF126,ISG15,TUBA1A,HSP90AB1,TRIM35,RPLP1,CBL,TRAF6,UBE2D1,SIAH2,MARCHF5,WWP2,TRIM8,PRPF19,SQSTM1,RNF113A,SYVN1,RNF34,TRIM10,TRIM3,HECTD1,RNF103,RNF146,WWP1,TRIM68,WSB1,MYLIP,PDCD5,SMURF1,DAPK3,TRIM54,UBASH3B,TRIM27,RNF122,STUB1,MARCHF3,TRIM23,BFAR,FBXO7,TRIM32,RIGI,FBXO25,RBCK1,TRIM63,POLL,HUWE1,NEDD8,RNF115,ANAPC11,RING1,RNF167,NOSIP,RNF8,RNF181,TOPORS,PPP4C,ZNRF1,TRIM62,MDM2,DCUN1D1,FZR1,TRIM45,RNF128,AREL1,H2AC4,CRBN,MUL1,CSNK2A1,HDAC6,NFKB1,RNF14 |
| 1.422e-07 | -15.77 | SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1) | protein interactions | 6598 | 350 | 143 | 19454 | 5460 |
CALR,ERCC3,GTF2E1,COPS5,H2AC4,LY96,MED21,BRD3,ZNF688,H2AZ1,RB1,PSMB1,TOP1,KLF1,CAND1,CXCL11,MXI1,PTP4A3,CDK9,TP53,SOX9,ING1,MAP1LC3B,TAF1D,H2AX,CDK8,OTX2,BHLHE40,SNIP1,PPP1R12A,ZC3H11A,KPNA2,MDC1,AKT1,SMARCA5,PPP1CC,KPNA6,NONO,GORASP2,AR,ATP5F1A,RUNX1,MECP2,UBN1,EIF4A3,CCNF,MRPL53,PTEN,MACROH2A1,ING2,TRIM27,KCTD9,NMI,DEK,SRC,SCML2,SF3A1,ELP3,CNP,CCNH,GRM2,SAMM50,TFIP11,CYB5D2,SQSTM1,TNFAIP1,SMC4,NUCKS1,KDM1A,SS18,MBD3,LDOC1,WWP2,BAZ1B,HMGA1,TRA2A,ACTL6B,BCL7C,XPO1,HNRNPD,RB1CC1,CDC23,ARL11,SIN3A,DNM2,BRD9,XPO5,SPTAN1,TRIM35,E2F4,RAF1,SAP30,SOX2,JUN,NCSTN,EZH2,RPN1,HGS,MTA2,SMARCB1,RBPJ,RINT1,TOP2B,BCL7B,PICK1,ASF1A,RBBP7,PAX6,SSRP1,CUL3,HNRNPC,MYC,CREBBP,DRAP1,CPSF2,SMARCE1,BRCA1,LMNB1,FAS,DLST,RAN,GTF2F1,SEC61B,MCPH1,PRMT5,FBXO22,RBBP4,ACTB,ESR2,USP5,GADD45G,ACTL6A,LNX2,PPP1CB,CCL21,FOS,SMARCD3,HIRA,DPH6,EP300,DDIT3,SAP18,ZDHHC17 |
| 1.426e-07 | -15.76 | MRPS10 (mitochondrial ribosomal protein S10) | protein interactions | 55173 | 218 | 97 | 19454 | 5460 |
MRPS23,MRPL24,RBM42,TRMT10B,PRR3,KRR1,SSBP1,MRPS9,SDHB,SRP14,NOL12,RPS2,TMEM70,CHCHD1,SNRNP70,E4F1,GRSF1,MOV10,MRPS18C,MEPCE,FASTKD5,MRPS18B,RPL23A,GFM2,NDUFS3,METTL15,AURKAIP1,APOBEC3D,MRPL11,ROMO1,MRPS28,DNAJC19,IGF2BP1,RC3H2,TUFM,RPL26,CRYZ,RPL4,GFM1,BAP1,MTRES1,ZNF574,MRPS34,RBMS2,KLF12,GTF2H4,RMND1,KCTD10,HNRNPL,GATD3,RPL9,ARMC8,POU5F1,MRPS26,MRPL18,RHOG,DDRGK1,TRA2A,HNRNPA1,RPL6,BAZ1B,MTRF1,IMMP2L,MRPS17,SRSF4,SRSF7,MRPS11,HINT2,PPAN,HSPD1,OTULIN,RPL18,H1-3,RAF1,RPL10,RPL19,RPL35,RPL7L1,MRPL23,RPS9,CCDC90B,MTG1,TACO1,MCAT,RPS5,MRPS25,BAG3,PMPCA,MYC,AUH,MTG2,MRPS7,NOP53,HSCB,EXD2,SNRPA,NGRN |
| 1.440e-07 | -15.75 | MTRES1 (mitochondrial transcription rescue factor 1) | protein interactions | 51250 | 289 | 122 | 19454 | 5460 |
OXCT1,PHB2,MRPL57,TRA2B,NDUFS2,MRPS7,NGRN,HADHA,ATP5F1E,MRPL34,ATP5IF1,MRPS18A,MED23,ATP5PO,NDUFA5,MRPL12,NDUFAF3,PRDX3,MED17,MRPL23,ATP5F1B,NDUFAF4,DLST,MTG1,TACO1,MRPL13,NOA1,MRPS25,PYCR1,PMPCA,HNRNPAB,MRPL16,ETFA,KGD4,ATP5F1D,HNRNPDL,RPS27A,MRPS17,THNSL1,PREPL,MRPS11,COX8A,HINT2,PDHA1,NDUFS6,NDUFA12,ETFB,HSDL2,HNRNPL,PNPLA8,NDUFS8,PHB1,MRPL18,MRPS26,MRPS35,STOML2,CLPX,MRPL9,NDUFV2,MRPL40,MRPL41,NME4,MRPL17,PDHB,MRPL20,POLDIP2,GRPEL1,IDH3A,GFM1,DLAT,TWNK,QRSL1,MRPS34,CDK1,MTRES1,CFTR,NDUFAB1,MRPL10,MRPL53,ACAT1,MRPS28,MRPS16,PYCR2,NDUFAF2,HSPE1,MRPS33,PDE12,MRPL22,FASTKD5,MRPS18C,ATP5PF,MRPL52,HSD17B10,THG1L,MRPS18B,NDUFS3,MRPL51,MRPL49,MRPL33,MRPL47,NDUFA2,ATP5PB,BCS1L,METTL15,PPIF,HADH,MRPL50,MRPS23,MRPL24,ATP5PD,DBT,ALYREF,COX4I1,MGME1,SDHB,SYNCRIP,MRPS9,SLC2A1,TRMT5,GRSF1,LYPLAL1,COPS5 |
| 1.461e-07 | -15.74 | SRPRB (SRP receptor subunit beta) | protein interactions | 58477 | 318 | 132 | 19454 | 5460 |
USP16,FBXO22,ESR2,MAD2L2,LMBR1L,SF3B4,RMDN3,SEC61B,NTRK3,MYC,CUL3,TMED4,RAB11A,RHEB,TOMM40,CASP4,GOSR1,RNF5,NPTN,UCHL3,STAU1,RER1,ADRB2,TMEM106B,PMAIP1,MIA2,TTC1,PLAA,FDFT1,BET1,PGRMC1,OTULINL,RND2,SEC62,RAB6A,TIMM29,RHOH,EGLN3,RMND1,PHB1,DUSP6,RFX5,STX5,CDK5RAP3,RHOG,LAMP2,DDRGK1,ARL5B,KRAS,G3BP1,S100A10,SAR1B,RAB18,CYP2C9,TMT1A,UBE3A,EZH2,RPN1,PTRH2,RAB4A,RND3,RAF1,DCAKD,DNAJC25,TMBIM1,NCSTN,ERLIN2,NDN,RHOJ,SNX3,TECR,UBE2L3,VIRMA,SEC63,CCNF,PSPC1,METAP2,MRPS28,SEC61A1,SRP54,SMPD2,EPHA2,UBE2H,TRIM32,RETSAT,SUGP1,USP14,DAD1,RPA3,TMX2,SYVN1,DERL1,LMNA,RPA2,SSR1,EPHX1,TM9SF1,UBE2M,LEMD3,ATG16L1,SPR,UQCRC1,CDC42,ST7,ANKRD46,DNAJC1,RPS16,PTP4A3,PTPN1,SRPRA,RCHY1,HSD17B11,TES,RAC2,POR,ESYT1,DHRS7,PSEN1,RDH11,FAF1,STX8,RNF167,PQBP1,SLC16A1,RAB13,STX18,IGF1R,SRP72,UBL4A,CCDC47,PREB,PPIF |
| 1.467e-07 | -15.74 | OVOL2 (ovo like zinc finger 2) | protein interactions | 58495 | 126 | 63 | 19454 | 5460 |
AIF1L,HDAC3,UNC45A,POLDIP2,NRBF2,XRCC5,JAGN1,DDX5,IPP,HNRNPH3,WDR77,TOM1L2,SIPA1L1,CDC42,TMOD3,STAT1,UBE2V2,CTNNA1,EFHD2,ARF1,MACROH2A1,CSNK2B,PRMT5,H2AZ2,IVNS1ABP,LAMTOR1,SMAD2,LRP6,HSP90AA1,SUB1,SMARCA5,BAG3,RUVBL1,THRAP3,SSRP1,CTNND1,ARF4,RPS27A,RBM3,SCYL2,PPP1R12A,SEC11A,HECTD3,ZNF526,TNPO2,FNTB,DDX39A,ARF6,DHX15,MDM2,CDK9,AIFM1,SMAD3,H2AZ1,PPM1B,SMAD4,NME2,KARS1,CTNNB1,TRA2A,PID1,CSNK2A1,HNRNPA1 |
| 1.469e-07 | -15.73 | TBC1D5 (TBC1 domain family member 5) | protein interactions | 9779 | 83 | 46 | 19454 | 5460 |
RAB4A,NGB,TFRC,MAP1LC3B,GABARAPL1,FBXL7,KRAS,RIGI,CCAR1,ZBTB25,EIF1AD,VPS26B,RHOG,STYK1,YWHAB,CBL,VPS26A,EDEM1,ATG9A,YWHAH,XPO1,YWHAG,SNX1,RHOH,SNX2,HNRNPL,RAC2,MAP1LC3A,PICALM,RPA2,GABARAPL2,CDC42,PML,RPA3,RAB9A,YWHAZ,SNX5,SFN,CUL3,LRRC73,RAB11A,CSK,SNX3,RHOJ,ESR2,AP2M1 |
| 1.477e-07 | -15.73 | NDUFV3 (NADH:ubiquinone oxidoreductase subunit V3) | protein interactions | 4731 | 174 | 81 | 19454 | 5460 |
RHOG,CHCHD1,TMEM70,MRPS26,DNAJC4,NDUFB8,MTRF1,GRSF1,MOV10,NDUFV2,NDUFS8,RMND1,SLC25A12,AIFM1,SSBP1,NDUFB4,COX4I1,SSMEM1,GATD3,NDUFA1,PDHA1,AQP3,NDUFS6,NDUFS3,GFM2,NDUFA12,CRELD1,MRPL11,TP53,NDUFA2,YIPF3,METTL15,DNAJC30,FASTKD5,IMMP2L,NDUFB5,SFXN1,CLPB,HINT2,COX8A,SAYSD1,HTRA2,DNAJC19,MTG2,AUH,NDUFAF2,NDUFB7,NDUFB6,NDUFB10,PMPCA,H2BC9,TUFM,PARL,LMBR1L,TACO1,MTG1,CCDC90B,SERINC1,CYBC1,WRAP53,VAPB,VPS18,MTRES1,NDUFA5,SLC25A3,TIMMDC1,CDC42,NDUFAB1,TIMM29,HSCB,NDUFS2,PHB2,SLC25A51,CRYZ,TMX2,NGRN,EXD2,PHYHIP,GRIA2,GFM1,NDUFC2 |
| 1.483e-07 | -15.72 | TLR2 (toll like receptor 2) | protein interactions | 7097 | 48 | 31 | 19454 | 5460 |
TMOD1,HSP90B1,STX17,MAP2K1,TIRAP,SMAD1,LGR4,FBP1,ATG16L1,CD14,TICAM1,AP1M1,ANP32B,TOLLIP,HMGB1,TLR2,MYD88,BMPR1A,PIK3AP1,IRF3,CLEC7A,LY96,TLR10,SFTPA1,AKT1,PIK3R1,CREBBP,TLR6,TLR1,STAT5A,HRAS |
| 1.503e-07 | -15.71 | response to ethanol | biological process | GO:0045471 | 126 | 65 | 18204 | 5365 |
SOD1,PSMD14,RPL15,CNR1,CYP7A1,CLDN3,OPRK1,IL2,CLDN1,CD14,TACR1,G6PD,MYD88,CBL,NQO1,CDO1,TYMS,TUFM,CRHR1,CHRNB2,OGG1,MSTN,PRKCB,PRKCE,USP46,GLRA2,ELK1,NPPC,RPL10A,FOS,PAX6,SETD7,EPS8,PPARA,OPRM1,DRD3,LEP,S100A8,CDK1,RGS2,DMAP1,HSPA8,GABBR1,ATP5F1A,UGT1A1,SOD2,BGLAP,KCNMB1,BIRC2,SLC23A2,IL13,TP53INP1,CRHBP,BAK1,CTSK,DBH,IGF1R,GLRA1,ST6GAL1,GNRH1,RGS19,TNF,ADIPOQ,POLB,SLC6A3 |
| 1.511e-07 | -15.71 | RALGAPA1 (Ral GTPase activating protein catalytic subunit alpha 1) | protein interactions | 253959 | 71 | 41 | 19454 | 5460 |
APEX1,DYRK1A,CAV1,VIRMA,STX6,DIRAS3,LMAN1,SLMAP,NKIRAS2,RHOJ,RHOH,HNRNPL,GFOD1,AP2M1,RAB35,HRAS,STYK1,YWHAB,YWHAZ,RHOB,RHOG,DNAJC5,YWHAG,YWHAH,LAMP3,RAB11A,SFN,MYC,DPP4,RAB2A,LAMP2,STX7,KRAS,RAB9A,MEA1,RHOU,SGIP1,RND3,RAB4A,CDC42,DLG3 |
| 1.511e-07 | -15.71 | UNKL (unk like zinc finger) | protein interactions | 64718 | 71 | 41 | 19454 | 5460 |
SMAD2,PPP1R16A,CPSF2,MGAT5B,MCM4,BAG3,NTAQ1,PSMA4,CUL3,DDX50,PRPF19,CDC5L,SRPK2,SMURF1,GGPS1,PSMB6,KCTD9,PSMB1,PRMT5,ATXN1L,PSMA6,PSMB5,ACACA,TFIP11,CTBP1,APOBEC3C,FRS3,EXOSC8,SMAD1,PSMB3,TOP3B,TRIM63,CRYBA2,KDM1A,PSMA1,PSMA5,HNRNPF,PSMA3,PABPC1,RPS28,PREPL |
| 1.518e-07 | -15.70 | NAP1L1 (nucleosome assembly protein 1 like 1) | protein interactions | 4673 | 324 | 134 | 19454 | 5460 |
VDAC1,RPS4X,RAD21,SSRP1,RPL31,MYO1B,COX8A,EZH2,H2BC1,NGB,CHMP4C,EIF1AX,RPL18,B3GNT2,RAF1,ASPM,ISG15,SOX2,INA,SUMO2,OSBP,EGLN3,DIRAS3,RPL9,RPL8,PHB1,MAGED2,COPS2,PPM1B,CDC23,HSPB1,RPL23,WWP2,RPL6,XPO1,DDRGK1,UFL1,GPC1,LCA5,EP300,CFDP1,PPT1,RPL27A,KCND3,SUPT4H1,LGALS3,RBBP4,APEX1,RPL19,ESR2,JAK2,LMBR1L,VDAC2,DLST,EIF3K,RPL37A,GTF2F1,FAS,MED10,BRCA1,SP1,H1-1,ILK,MYC,CREBBP,CUL2,NOP16,CUL3,TOMM40,BAG3,HUWE1,H3C1,VRK1,FBXO25,MEPCE,RPL17,RPL23A,HAPSTR1,HSD17B10,TFCP2,CAPZA2,TP53,H2AX,AURKAIP1,FNTB,RPL15,FZR1,CAND1,PRNP,ZBTB2,NAP1L5,H2AZ1,GTF2B,RPL12,ALYREF,RPL24,H2AC4,SNRNP70,RPL10A,CSNK2A1,COPS5,NR2F6,HDAC6,RPS15,FBXW7,BAP1,RPA3,PPM1G,THUMPD1,PML,SIRT7,RNF113A,RPA2,UBE2M,HEXIM1,HECTD1,ATG16L1,UBA52,CFTR,DYRK1A,VIRMA,RPS3,CCNF,ZNF330,CTNNA1,CSNK2B,MACROH2A1,CHORDC1,BICD2,RC3H2,PDCD4,UBE2H,PPP1CC,USP14 |
| 1.540e-07 | -15.69 | SNRNP27 (small nuclear ribonucleoprotein U4/U6.U5 subunit 27) | protein interactions | 11017 | 166 | 78 | 19454 | 5460 |
CD2BP2,RAF1,RBM12,NAA15,H2AJ,FEN1,SNRPE,PPME1,CARD19,CHMP4C,NHERF1,HINT1,ARGLU1,ZYX,SAR1B,SNRPG,MEPCE,VRK1,LASP1,CTNNBL1,DHX16,KRAS,PPIL4,IFI16,UQCR11,ANKRD50,PDCD10,RPRD1A,NUP35,ZBTB2,RBM42,CGGBP1,MAPRE2,LSM5,SNRPA1,ARF6,ETF1,EHHADH,SNRPN,PPP1R8,SUMO1,WDR5B,SF3A1,HECTD1,OXSR1,PICALM,PAK2,USP39,RPRD1B,STK26,PMAIP1,PRPF4,DDX46,PSENEN,ANAPC15,PTPN11,NAA50,RAB2A,HSPA14,MYC,UBE2H,HTRA2,ARMT1,PEA15,CHORDC1,GTF2F1,EZH1,CYB5R3,EFHD2,VAMP3,SRPK2,ESR2,TNPO3,DUSP3,IFI6,SPCS1,SNRNP40,SNX3 |
| 1.546e-07 | -15.68 | RNA splicing, via transesterification reactions | biological process | GO:0000375 | 255 | 114 | 18204 | 5365 |
RBM5,SNRPD2,RBM42,COIL,HNRNPF,CDC5L,PRPF19,DHX15,DDX39A,FRA10AC1,LSM3,GCFC2,PABPC1,SNRPA1,CD2BP2,RSRC1,SNRPE,HNRNPC,SMU1,IK,TRA2B,PRPF18,PRPF31,SART3,CWF19L1,SNRPD1,LSM8,SF3B5,PPIH,CWC15,TXNL4A,CASC3,MFAP1,WDR77,SRSF2,RBM17,SF3B1,SRSF8,SRPK2,GEMIN8,SNRPD3,MAGOH,SMNDC1,LSM2,SNRPN,ZMAT2,EIF4A3,WDR83,DHX9,DBR1,PRPF4,SRSF7,SF3A1,HNRNPH3,LSM4,SNRNP27,PRMT5,UBL5,LSM6,KHDC4,SRSF10,CELF6,SRSF4,MPHOSPH10,DDX46,CTNNBL1,SYNCRIP,PQBP1,BUD31,ESS2,TRA2A,PPWD1,RBM22,SNRNP40,ZCRB1,RNF113A,METTL14,CDC40,DHX16,SNRPG,SNRPA,TFIP11,SNRNP70,DDX42,DDX1,SNRPB2,HNRNPA1,DDX23,NCBP2,DDX5,LSM5,SLU7,MAGOHB,DDX39B,DHX38,SCNM1,PPIL3,HSPA8,SNIP1,SRSF1,GEMIN7,NOVA1,HNRNPA2B1,RBM41,SRSF12,SNRPB,HNRNPK,USP39,SMN1,SF3B6,RBMX2,TSSC4,SF3B4,LUC7L3 |
| 1.549e-07 | -15.68 | SRP54 (signal recognition particle 54) | protein interactions | 6729 | 134 | 66 | 19454 | 5460 |
TES,SRP14,PTPN1,CDC5L,EGLN3,TMPO,DERL2,HNRNPL,FZR1,RPS16,DNAJC1,XPO1,WWP2,MRPS11,BAG2,DHX9,RPL31,FKBP8,SMN1,MRPS18C,SRPRB,CSE1L,KRAS,G3BP1,SOX2,MRPL11,RAF1,SERPINA1,SRP72,RPS11,DNAJC2,DMAP1,STIM1,SEC61B,SRP54,GSK3A,METAP2,PSPC1,SF3B6,RPL19,VIRMA,ESR2,PRKCE,DNAJC5,MYC,MAPRE1,UBE2H,RIT1,DERL1,STK26,HSPA8,PML,RPA3,G3BP2,SMC4,STAU1,RPL4,DUSP22,SEC62,MND1,TPT1,SF3A1,SSR1,MED23,CPLX2,RPA2 |
| 1.557e-07 | -15.68 | CLEC16A (C-type lectin domain containing 16A) | protein interactions | 23274 | 622 | 233 | 19454 | 5460 |
HDAC6,HM13,GMPPA,ISYNA1,GMPPB,ORC5,DNAJC7,EXOC2,PSMD7,NME2,GTF2A2,SLC2A1,PSMB1,SLC25A12,NKIRAS2,COG1,BCS1L,MTARC2,MAP2K3,SELENOK,TBK1,TMEM126A,CCDC47,DHRS7B,ACTR2,PC,MSH6,CTNND1,PSEN1,NSMCE3,DNAJC30,CAMK2G,HUWE1,PPP1CC,KPNA6,CIAO1,GGCX,XPOT,CDC73,STK24,ASCC1,SFXN2,TRIM27,STUB1,VIRMA,SLC25A4,COPE,CNP,SLC35E1,SNRPN,COQ8B,RBFOX2,RABL3,HNRNPH3,MRPS34,ARPC2,IDH3A,PPM1G,RPA3,UQCC3,WDR11,SAV1,MAP1S,DYRK1B,AHSA1,VPS4A,RASSF8,PSMD10,DDX23,IGBP1,PSMB4,PPP2CB,DNM2,STK3,NDUFS8,ERLIN1,FAF2,RAF1,OTULIN,POLR2C,DTWD2,NME1,RIMOC1,VPS26B,PRPSAP1,NDUFA4,RFC3,SACM1L,MCM6,DHX16,MCM4,PMPCA,PYCR1,RAB11A,MTG2,CNIH4,RMDN3,CDC7,PIGK,CPSF1,FAM91A1,NDUFAF4,GNB1,UMPS,ACTB,RANBP6,TIMM29,PPP1CB,PRDX3,TOR1AIP2,WDR77,NDUFA5,ARCN1,ARMCX3,LARP4B,VAPB,NUBP2,RLIM,PSMA3,ATP5MK,HSDL1,UNC45A,SKP1,RADX,MCMBP,ATAD1,RBFOX3,ENY2,ACOT8,TSNAX,KPNA1,TAF9,COQ8A,ILVBL,RAB39B,TMPO,CAND1,ACTR1A,IPO8,CDK4,PREB,TMEM165,ARPC3,ACADSB,DISC1,TRAFD1,FKBP8,POLE4,TOR2A,SRPRB,NUP107,PSMA5,ARHGAP21,EXOC5,RAB2A,SMARCA5,GEMIN8,DNAJC10,CISD1,RAP2C,PTPMT1,SEC61A1,CDIPT,SF3B6,DYRK1A,CTSB,MKKS,MRPL10,GTF3C4,ACACA,TFB1M,UBE2M,IDH2,SAMM50,HPS6,EXOSC4,POLD2,PSEN2,TMEM263,FTSJ1,HDAC3,STK4,IQSEC1,YWHAH,RAB5C,SEC61A2,ZCCHC10,DCAF5,HDHD5,COCH,HNRNPL,RAB1B,KIF2A,ETFB,NDUFA12,UCK2,PDIA6,RABGGTB,MYO1B,SECISBP2L,PSMA2,PSMA1,USP30,MLF2,COX11,SNRPB,PCCB,SLC1A3,POLR1B,DNAJB6,KBTBD6,APEX1,POLR2B,PSMB6,PSMD6,TAMM41,STAT1,NDUFAF3,YIPF5,PSMB3,NUP62,TRMT112,UBAC2,STK26,CNKSR3,RNF41,HIGD2A,SSR3,TIMM17A,NDUFS2,UFL1,EMC1,FXR2 |
| 1.563e-07 | -15.67 | PSMF1 (proteasome inhibitor subunit 1) | protein interactions | 9491 | 98 | 52 | 19454 | 5460 |
PSMC3,RNF126,NHERF1,ADAMTS1,CD2BP2,PSMB9,TRAF2,TBK1,RIGI,UBE2A,PSMA5,PSMA1,PSMA2,SEM1,MRPS11,PSMG2,WWP2,PSMD3,EGLN3,RAB33A,HNRNPL,PSMB1,PSMB4,CTBP1,PAK5,PSMB7,SPMIP6,RALYL,SNRNP27,PSMB3,LNX2,HOXB8,RBFOX2,PSMC4,SKP1,PSMC1,LDOC1,HSPA8,DVL2,H1-1,PSMG3,STK11,CYP1A1,CCDC85B,PSMD1,FBXO7,PSMA4,PSMB2,PSMD6,PSMD4,PSMA6,CCNF |
| 1.569e-07 | -15.67 | STIM1 (stromal interaction molecule 1) | protein interactions | 6786 | 377 | 152 | 19454 | 5460 |
FKBP8,EDEM2,RAB3B,NUP107,IGF1R,STX18,NSDHL,SFTPC,SURF4,LBR,CLEC2B,INSIG2,SNAP29,PREB,CCDC47,LMAN1,TMPO,STX6,PRNP,DNAJC1,ARF6,RAC2,CDCA3,METTL6,HSD17B11,CAMLG,PTPN1,SRPRA,OSBPL8,STYK1,ESYT1,POR,TRPC1,LAMP3,HM13,SLC25A46,DHRS7,EI24,TMEM199,TMEM209,YKT6,SLC7A1,MTDH,DERL1,RAB9A,RTN4,SYVN1,LGI1,RPA3,SLC39A9,TEX264,LEMD3,PDCL,USE1,SSR1,HSP90B1,GRM2,TMX4,FGFR1,LMNA,RPA2,ST7,TMEM106A,CDC42,SEC22B,ARHGAP1,RABL3,SEC63,RHOJ,ZNF622,SRP54,ATL1,GXYLT1,CCNF,CD1E,MAPRE1,SDF2L1,HMOX2,GORASP2,EXOC5,HSPA14,SAR1B,RETREG1,KRAS,TMT1A,RINT1,CYP2C9,PLD3,RND3,PTRH2,RAB4A,STIM1,RPN1,IFNGR1,DNAJC25,FAF2,STBD1,MACO1,COX14,SLMAP,EGLN3,CD1A,RHOH,CYB5A,STX5,GJA1,RAB35,YWHAB,AHSA1,C2CD2L,CDK5RAP3,RHOG,DDRGK1,YWHAH,LRRTM1,YWHAG,MARCHF5,RAB5C,LAMP2,PXMP2,STX7,STAU1,UFL1,HSCB,RAB5A,RABAC1,HEXB,VAPB,CNPY3,RND2,OTULINL,SEC62,PGRMC1,TOR1AIP2,ESR2,ATP6AP2,REEP4,IP6K1,SEC61B,RMDN3,ARF1,LMBR1L,VMP1,H1-1,SCFD1,NTRK3,FIS1,LMNB1,YWHAZ,GGH,RAB11A,VEZT |
| 1.587e-07 | -15.66 | CISD2 (CDGSH iron sulfur domain 2) | protein interactions | 493856 | 224 | 99 | 19454 | 5460 |
HMOX2,SLC35B4,UBE2H,CISD1,CYBC1,CDIPT,SEC63,VKORC1L1,COPE,ST7,TMEM106A,CDC42,CHRNB2,SSR1,LMNA,RPA2,DERL1,TMEM243,SQSTM1,RAB9A,RTN4,LRP10,RPA3,ATP1B1,LAMP3,ADIPOR2,BTN2A2,ESYT1,SPP1,RAC2,HSD17B11,COX4I1,IER3,PTPN1,AIG1,TMPO,DNAJC1,ARF6,MTCH2,IL1R2,CENPM,TBK1,CCDC47,TLR3,LTBR,RUSF1,FKBP8,RAB3B,GPR37L1,LRP3,NSG1,VMP1,LMNB1,SEC61B,VDAC2,LMBR1L,TAX1BP1,OTULINL,SEC22A,SEC62,PGRMC1,BET1,EHHADH,VAPB,RAB5A,AKAP1,DNAJC22,PXMP2,STX7,SLC31A1,LRRTM1,MARCHF5,RAB5C,PLPP4,TSPAN10,ATG9A,LAMP2,HNRNPD,C2CD2L,AGR2,FAM241B,RHOG,KCNA2,RAB35,OSBP,DNAJC25,PGAP2,STX12,CRELD1,STIM1,RPN1,TMT1A,NDUFA4,IMMP2L,SACM1L,LEPROTL1,VDAC1,MYORG,KRAS |
| 1.595e-07 | -15.65 | IKZF3 (IKAROS family zinc finger 3) | protein interactions | 22806 | 301 | 126 | 19454 | 5460 |
H1-3,SPG21,RPS7,CKS1B,MTA2,SMARCB1,RPS11,STK16,SNRPE,TUBB4B,RUVBL2,TRIM21,OAZ3,RPS24,FHL3,HSPD1,SLC25A5,HNRNPA2B1,RPL28,PAX6,FANCG,ENKD1,CHCHD2,RBBP7,HNRNPF,PSMA1,RUVBL1,HNRNPA1,PRDX1,HMGA1,PRPF19,PIK3R1,PFDN5,STAMBPL1,RPL23,BCL2L1,ARMC8,RPLP2,SIN3A,CBFB,PPIA,EGLN3,HNRNPL,LMO4,CDKN1A,H1-5,ACTL6A,TRAPPC6A,FRS3,HSPA8,HDAC5,STK26,DDX5,ATPAF2,SAP18,EEF1G,SNRPB,LMO2,IKZF2,CDKN2D,HSP90AA1,EXOC8,ARMC7,RBBP8,SNRPD2,CDC7,FOXP3,ZMYM2,CPSF1,SCNM1,MAD2L2,TCAP,RBBP4,EEF1A1,ESS2,IKZF5,CDK4,GRAP2,ILF2,CBX3,EFHC1,RPL23A,DHX9,EMC2,STX11,KPNA2,HNRNPK,CRYBA4,GAPDH,USP2,TAF9,RPS2,CRBN,NXT2,RPL24,RPL12,HRAS,SYNCRIP,PPP1R18,TOP1,RPS14,ATG16L1,CCND1,SUMO1,ING5,GID4,NHP2,MBD3,LDOC1,HSPA5,KDM1A,HMGB1,PIK3R2,NTAQ1,RUNX1,NONO,CTSD,CCHCR1,UBE2I,ALB,MRPL53,ENO1,LDHA,MAGOHB,BUB3,YES1 |
| 1.606e-07 | -15.64 | SLC10A6 (solute carrier family 10 member 6) | protein interactions | 345274 | 177 | 82 | 19454 | 5460 |
TMEM50B,SFXN1,RUSF1,STX8,UNC50,SLC35G2,OR7D4,ERG28,TF,TMEM60,FKBP8,SACM1L,SFT2D2,PSEN1,SELENOK,NEU1,MFSD6,NRM,TMEM252,UBIAD1,CTSA,CYB5B,TMEM14B,STX12,COMT,TMEM14A,COX20,FA2H,SLC66A2,MFSD5,ANKRD46,AIG1,TSPO2,CNIH1,FUNDC2,SLC38A7,TMEM208,SLC25A46,SYNJ2BP,SLC41A1,TMEM107,EMC6,SCAMP5,TMEM11,FXYD6,BTN2A2,C2CD2L,ZDHHC15,ORMDL1,JAGN1,SLC39A9,DERL1,TMEM203,TMEM243,PSENEN,SLC7A1,STX7,PIP4P1,GOSR2,SEC22B,CFTR,VAMP1,CCDC167,PLP2,SMCO4,PIP4P2,FAM3C,CYB5R3,VAMP3,CDIPT,PLP1,TMEM229B,SYNGR1,TVP23B,THBD,TECR,GJB2,SLC35B4,FAXDC2,SLC38A1,FMO1,FIS1 |
| 1.612e-07 | -15.64 | Dectin-1 mediated noncanonical NF-kB signaling | REACTOME pathways | R-HSA-5607761 | 61 | 39 | 10285 | 3229 |
PSMD7,SEM1,PSMB9,PSME1,PSMB4,PSMD6,SKP1,UBA3,PSMD10,PSME2,UBE2M,PSMD4,UBB,RPS27A,UBA52,PSMA1,PSMD14,PSMC3,PSMC4,PSMC1,PSMD12,PSMB5,PSMA3,PSMB1,MAP3K14,PSMB7,PSMD3,PSMA6,PSMB3,PSMD1,PSMB2,FBXW11,PSMA2,PSMB6,PSMA5,PSMB10,PSMB11,PSMC5,PSMA4 |
| 1.617e-07 | -15.64 | WDR1 (WD repeat domain 1) | protein interactions | 9948 | 199 | 90 | 19454 | 5460 |
SPOP,MAPRE1,UBE2H,AKT3,PCBD1,USP14,RGN,CFL1,CFL2,TXN,NDN,DAPK1,LDHA,CTSB,SH3BGRL,CTTN,ENO1,MSN,CSNK2B,MOB4,LDHAL6B,RPA2,CFTR,FBXW7,UBE2K,TXNDC17,BAP1,RPA3,PPIH,PRDX6,PSMG4,SYVN1,HSPB2,NME2,GMPPB,CALR,MOV10,DPP4,HDAC6,DSTN,CAPZA2,TFRC,UAP1,CBX3,NUPR1,PPME1,TP53,MVD,GGCT,FARSA,HSPE1,NUP107,RIGI,ABCE1,ATG3,VMP1,RIT1,LDHB,CUL3,MYC,GALE,BAG3,ACTB,STAT1,APEX1,ATP6AP2,ENO2,CTBP1,ADSS2,GSTO2,PPP1CB,OXCT1,FOS,DDX39B,HSPA8,BIRC2,AGR2,UBE2D1,SYNJ2BP,CTNNB1,TYMS,CHMP4C,NME1,EZH2,TOP3B,ISG15,SOX2,KRAS,RBBP7,SAR1B |
| 1.630e-07 | -15.63 | STX1A (syntaxin 1A) | protein interactions | 6804 | 188 | 86 | 19454 | 5460 |
CPLX1,PLPP6,VPS16,STX11,PSEN1,VAMP8,TNF,TMEM60,SLC6A3,SNAP23,RAB27A,CDK5,GPM6B,ERG28,STX8,CYB5B,STX12,AQP3,CHMP4C,VAMP2,NRM,PGAP2,SNAP29,AIG1,STX6,VAMP7,SNAP25,ANKRD46,VTI1B,STX5,SLC6A2,TRAF3IP3,BTN2A2,HAX1,STX1A,SYT4,CSNK2A1,CD81,CLEC1A,PLPP4,VSTM4,TMEM199,STX7,GPM6A,OIP5,PSMA3,TMEM254,JAGN1,FAM3C,CDR2,CMTM7,VPS18,USE1,CPLX2,VAPB,SDCBP,STXBP1,VAMP1,CFTR,SEC22A,SEC22B,AGTRAP,BET1,GOSR2,APEX1,DYRK1A,DAPK1,STX10,UBE2I,ETNK2,PLP1,VAMP3,CCSER2,TMEM100,KCNB1,PLN,NAPA,SLC6A1,SYP,STXBP6,STX16,SLC6A4,RNF40,VAMP5,TMEM41A,ZNF250 |
| 1.656e-07 | -15.61 | GATA4 (GATA binding protein 4) | protein interactions | 2626 | 401 | 160 | 19454 | 5460 |
NDE1,ACTL6A,H1-5,PGRMC1,SLC25A3,ATP5PO,HSPA8,SF3B1,DDX5,EP300,RFC4,XRCC5,FOS,SAP18,TRA2B,SRSF2,HNRNPA0,HAND2,PHB2,EEF1G,SMARCE1,PCCB,MLF2,CUL2,RAB11A,PYCR1,HNRNPAB,SP1,HSP90AA1,H1-1,DNAJB6,FYTTD1,CHTOP,ZMYM2,VRTN,INTS10,RAN,CYB5R3,MAD2L2,RPL10,ATP5F1B,MATR3,SOX2,RPS7,RAF1,RBPJ,SF3B5,MTA2,SMARCB1,SNRPE,RPS23,TUBB4B,RPN1,EZH2,RAB6B,EWSR1,RTCB,SLC25A5,MEF2C,HSPD1,NDUFA4,RBM3,HNRNPA2B1,RFC2,POLDIP3,FLOT1,HNRNPF,RBBP7,VDAC1,RUVBL1,YWHAG,HNRNPA1,PRPF19,BAZ1B,DDX1,HNRNPD,HSPB1,EED,CORO1C,BRD9,PHB1,DHX15,EDF1,RBFOX2,SF3A1,CPSF4,PAX9,UBE2M,HNRNPH3,MACROH2A2,CDK1,RPA2,CHMP1A,HNRNPH2,ARPC2,RPA3,NBN,MBD3,PIAS1,PIP4P1,HSPA5,SS18,KDM1A,RPS15,WDR3,HDAC3,GTF2I,HMGB1,ATP5F1A,KPNA6,NONO,TUFM,SMARCA5,SEC13,PYCR2,CDC73,ATP1A1,LCORL,AP2A1,PPIG,CDKN2AIP,CSNK2B,PSPC1,TUBA1B,LIG3,ZBTB33,EZH1,MAGOHB,BUB3,ATP5PB,MTA3,TP53,TOPORS,ILF2,PHC1,IK,ZNF787,BHLHE40,SLC25A11,SNRPG,MSH6,MDC1,RPL17,THRAP3,KPNA2,CSNK2A1,TMA16,TPM3,ELOC,CALR,ID1,AKAP8L,RPL24,SNRNP70,GATAD1,SSBP1,ALYREF,RPL32,TOP1,PRNP |
| 1.656e-07 | -15.61 | SNRPB (small nuclear ribonucleoprotein polypeptides B and B1) | protein interactions | 6628 | 488 | 189 | 19454 | 5460 |
PHB1,IFIT2,DHX15,CACYBP,HNRNPA1,PSMD3,PRPF19,HNRNPD,SKIC8,DDX23,SRSF7,FHL3,PCNA,HNRNPA2B1,HSPD1,UBE2A,PPWD1,SRSF4,JUN,PPP2R1A,RAF1,RBM12,SART3,SNRPE,POLR2C,SF3B5,CHMP4C,ZMAT2,SNRPD2,SNRPD1,RSRC1,CPSF1,PNMA1,ERH,SNRPB2,TUBB,PRPF31,CUL3,CUL2,NLRP3,ZCRB1,PSMA3,FAM168B,COIL,WDR77,MFAP1,USP39,CWC15,ZBTB2,NCBP2,THOC1,DCUN1D1,HDAC6,CRBN,ERG28,ZC3H11A,PQBP1,MDC1,SMN1,RIGI,SNRPG,THRAP3,TSSC4,CTNNBL1,HUWE1,LSM4,EXOSC8,DDX39A,CD2BP2,GEMIN7,ILF2,EIF4A3,VIRMA,YES1,DNAJC8,SKAP2,PPIG,CDC73,PPIH,KIN,PRPF4,RPA3,LSM8,SNRPN,SF3A1,TXNL4A,LSM2,METTL14,TOX4,WDR82,SRSF1,POLR2L,LSM5,SNRPA1,SNRPD3,HNRNPL,DDRGK1,WWP2,PFDN5,MAGOH,EWSR1,CMTR2,POLDIP3,HNRNPDL,CCAR1,SOX2,SUPT5H,TOP3B,SMNDC1,CAAP1,SF3B4,PRMT5,SMU1,ESR2,POLR2B,SNRNP40,TTC33,SNRPB,BTF3,HNRNPAB,HNRNPC,MYC,THOC6,ICAM1,CHTOP,RAB5A,DDX5,HSPA8,SF3B1,DDX39B,SNRPA,SAP18,STAU1,UFL1,TRA2B,HNRNPA0,ZC3H14,NCOA5,ALYREF,MRPS9,SYNCRIP,CDC5L,RBM42,NKAP,CAND1,FZR1,SPPL3,API5,COPS5,CD81,RBM17,LSM3,SNRNP70,DHX9,SNIP1,MEPCE,CDC40,SNRNP48,NUPR1,IK,DDX42,PHAX,GCFC2,SF3B6,SRPK2,SMURF1,PPP1R10,SUGP1,UBE2H,IGF2BP1,SERTAD3,GEMIN8,TRIM23,LSM6,CWF19L1,BAP1,DDX46,SNAPC1,HSPA5,OIP5,RBM22,PPP1R8,LUC7L3,HEXIM1,TFIP11,UBE2M,ZNF326,RPA2,RPRD1B |
| 1.661e-07 | -15.61 | G protein activity | molecular function | GO:0003925 | 46 | 31 | 18094 | 5411 |
RIT2,RAB11B,RALA,RERG,HRAS,RASL10A,CDC42,RAP2A,ERAS,RAP1A,RIT1,RASL11A,MRAS,RAB5A,ARF6,RASL12,GNA11,RAB1B,RALB,RAB5C,RAN,RASL10B,RAP2C,SAR1B,RAB1A,RAP2B,RAB27A,KRAS,RAB4A,RAP1B,RAB11A |
| 1.669e-07 | -15.61 | EIF3B (eukaryotic translation initiation factor 3 subunit B) | protein interactions | 8662 | 307 | 128 | 19454 | 5460 |
EIF3D,WWP2,DRG1,AHSA1,AGR2,RPLP2,EED,DYNC1I2,RPS10,EIF2S1,PAIP1,RPS7,RPS23,RPS11,BZW2,CHMP4C,VPS33A,RPS24,PABPC1,TRIP4,RPL31,RAD21,RPS4X,GNL1,EMC8,KRAS,PSMA1,G3BP1,MCM4,RPL39,RIOK2,BTF3,CUL3,MYC,LMO2,RIT1,SETD7,RPS5,RPS26,ICAM1,H1-10,BRCA1,SEC61B,CMTR1,EIF3K,FAU,APEX1,PRRC2A,EIF4A2,RPL27A,PIH1D1,NUFIP2,EIF4B,EMC9,EP300,RAB5A,HDAC5,RPS28,UPF3B,G3BP2,STAU1,GPC1,EIF1B,UFL1,CD81,CSNK2A1,USP3,ENY2,RPL10A,RPS2,CDK12,CD4,RPL32,SRP14,RBM42,NCBP2,TMPO,MDM2,RPS27L,FZR1,RPS16,TP53,RPSA,FBP1,SRP72,DNAJC2,TNNI1,RPL23A,ABCE1,RIGI,EIF3E,RPS13,MEPCE,EIF4EBP2,GPRASP3,IL2RB,UBE2H,ATP1A1,EIF3G,ASCC1,RPS12,RPS20,EIF2S2,METAP2,EIF4A3,PSPC1,RPS3,CCNF,RPL22,VIRMA,SMURF1,NREP,EIF3J,NDUFAB1,TPT1,RPS14,ATG16L1,UBE2M,HEXIM1,SSR1,RPA2,BAP1,RPA3,EIF4E,MRPL40,HMGB1,RPS15,NF2 |
| 1.669e-07 | -15.61 | UBE2D2 (ubiquitin conjugating enzyme E2 D2) | protein interactions | 7322 | 307 | 128 | 19454 | 5460 |
RTF2,RDH12,RNF7,VPS18,DUSP14,LNX2,RNF11,RNF5,BIRC2,TRIM5,TTC1,RLIM,RMND5B,RNF10,ARRDC3,PMAIP1,COP1,PHF7,BRCA1,RNF40,NFYA,CUL3,UBTD1,SIAH1,TRIM46,HECW1,ANAPC2,NFKBIA,RNF126,FBXL3,TRAF2,CSNK1E,RAF1,RNF26,AHCYL1,PELI1,UFM1,TRIM26,TRIM37,HECTD3,TRIM21,TRIM11,UBE3A,CDKN1B,CBL,UBE2D1,TRAF6,SIAH2,TRIM34,TAX1BP3,WWP2,TRIM8,MARCHF5,TRIM35,AASDHPPT,UBE2M,TRIM36,HECTD1,RAG1,RNF146,RNF103,UBE2F,WWP1,WSB1,MYLIP,TPT1,UBE2K,RNF34,SYVN1,SQSTM1,TRIM10,TRIM3,MARCHF3,STK11,UBE2H,HERC4,SPOP,TRIM23,RC3H2,BRAP,FBXO7,BFAR,ARL6IP6,TRIM32,CCNB1,SMURF1,UBB,UBE2L3,UBA3,TXN,THAP8,TRIM54,QSER1,TRIM27,TRAF7,UBASH3B,UBE2I,STUB1,ACOX1,RNF122,TOPORS,RNF8,RNF181,ZNRF1,TRIM62,MAP1LC3B,UBE2V1,TP53,RNF20,RIGI,HUWE1,RNF115,ANAPC11,NEDD8,TRIM63,RBCK1,POLL,RING1,RNF167,AREL1,MUL1,FCGR2A,NFKB1,RNF14,MDM2,TRIM45,MTAP,RCHY1 |
| 1.669e-07 | -15.61 | TIMM44 (translocase of inner mitochondrial membrane 44) | protein interactions | 10469 | 227 | 100 | 19454 | 5460 |
BET1,TIMM17A,UFL1,HSCB,EMC1,EXD2,NGRN,EP300,RAB5A,RBM27,DNAJB6,SERPINH1,RIT1,PMPCA,CUL3,RAB11A,MTG2,AUH,MYC,PARL,CCDC90B,MTG1,TACO1,PDHA1,OTULIN,RAF1,TUBA1A,CHCHD2,KRAS,RNF26,IMMP2L,NDUFA4,HSPD1,SLC25A5,COX8A,HINT2,RHOG,MRPS26,MTRF1,DDRGK1,PPIB,DYNC1I2,COX14,RMND1,EGLN3,HDHD5,FBXO32,GATD3,THY1,FGFR1,LMNA,RPA2,MTRES1,COQ8B,CFTR,SLC25A51,FBXW7,COL3A1,CRYZ,GRPEL1,RPA3,MAIP1,GFM1,RAB9A,SYVN1,PRKCB,DNAJC19,UBE2H,COL1A2,OAT,SUGP1,TUFM,GRPEL2,SLC25A4,VIRMA,MRPL53,PTPMT1,ACAT1,NDUFS3,GFM2,NDUFA2,MRPL11,METTL15,APOO,PPIF,AURKAIP1,SFT2D2,FASTKD5,SFXN1,IGF1R,EFHC1,TMEM70,CHCHD1,GRSF1,FZR1,COX4I1,COQ8A,AIFM1,SSBP1,TES |
| 1.677e-07 | -15.60 | protein-containing complex assembly | biological process | GO:0065003 | 1279 | 459 | 18204 | 5365 |
NUP153,HIGD1C,HIRA,PSMG2,RIC3,RRN3,TMEM126B,FAS,ANP32B,ASF1A,EIF3G,BAD,ATF1,ACACA,TUBA1A,MED31,TFG,MIS12,STXBP1,JAK2,TAF11,KCNS1,CAND1,PRMT5,CFAP73,LSM4,PRND,SDHAF2,FKRP,TAPBPL,GMNN,CLP1,FAM107A,AIFM1,KCND2,NOP53,RBBP4,SLC1A2,COPS7B,GEMIN8,RPSA,DR1,UQCC3,EIF3D,CATIP,WDR77,HSD17B10,NSG1,CALR,BOK,VAMP1,AQP4,NACC2,AQP11,EHD4,LPCAT3,UBE2S,COX7A1,TRAPPC1,FMC1,NOPCHAP1,DNM2,RTN4,RPL10,OTUD6B,TAPBP,MED27,RPLP0,SRSF10,GTF2A1,NDUFS3,H3C1,TPPP2,SMYD3,CHMP2A,SSBP3,CCDC65,KHDC4,MED29,SAR1B,AQP2,CRYZ,PALS2,PRNP,GNMT,LUC7L3,SF3B4,SNAP29,SNAP91,TRAF7,MAP4,SMN1,OTX2,KCNA2,HSPD1,MRPS7,NDUFB6,COPS7A,DDX39B,KCNF1,IMMP2L,STOML2,G3BP2,UBE2K,SNRPB2,DDX1,TXNL4A,VAMP3,PIAS1,XRCC5,NINJ1,ACOT13,CD2AP,SNAP23,CENPP,HP1BP3,TBCEL,TACO1,FKBP4,PRPF31,NDUFB5,SPMIP6,ATP5F1D,LRRC61,SSNA1,KCNJ8,PIH1D1,KCTD16,ALOX5AP,FGF13,NHERF1,GCFC2,CLXN,EHD3,CBR4,ARL6,PML,SNRPD2,SRPRA,KCTD3,NDUFA5,HSCB,FCHO2,MED22,CLU,KCNG3,COX19,NLRP1,MACROH2A2,MED10,CD40,MED30,TRIM32,COL1A2,TAF9,MED9,ASIC1,MED23,CLTRN,MRM2,SLC2A1,RS1,CRTC2,KCTD10,GPAA1,TCP1,PET117,COX16,NDUFAF4,TIMM21,EIF3K,NDUFB8,WDR19,CUL3,SSRP1,KCND3,PRKACB,TRAPPC4,TMEM199,SAMHD1,CAPZA2,LPXN,CELF6,TMEM170A,HIGD2A,COX17,NDUFB4,AP2S1,EIF3E,RRM1,SIGMAR1,SMARCB1,SNRPB,TRAPPC2L,KRIT1,COX14,TM9SF4,SF3B6,HSD17B8,EXT1,PTGES3,H1-3,NDUFB10,NDUFAF6,NDE1,H2BC17,SLC25A46,SRC,CALY,CLDN14,PPID,SMARCA5,UQCC2,ANGPT1,POMP,PDCL,CENPW,PRKRA,ADRM1,NLE1,TCAP,TAF10,TIAM1,COX20,NDUFAF3,NDUFS2,MED17,NUP107,TRAPPC3,BECN1,DICER1,LRRC8C,NAPA,FMOD,NDUFA2,PICALM,SF3B5,DLG1,NAP1L3,GPX4,SOX9,SART3,NAP1L5,SNRPA1,UBN1,SNRPE,CCT2,H2BC11,NLRP6,COIL,PRPF19,MACROH2A1,FARSA,SF3A1,TPPP,MAT2A,JCHAIN,SLC31A1,WDCP,CREBBP,ZNHIT6,KCTD15,ADRB2,WASF3,NDUFA1,CHRAC1,WASL,EIF3J,VAMP8,EIF2D,DHX9,NAPG,TWNK,NCK1,LSM2,SRPK2,KLHL12,SNRPD3,GTF2B,GTF2H5,SNRPG,CLDN1,RPL10L,RPS27L,IFIH1,H2BC9,TAF2,NDUFC2,H1-10,NAA60,TMEM70,HSP90AB1,KCTD17,MSRB1,AP2M1,RUVBL2,THG1L,MCOLN1,PFDN6,ARPC2,NDUFA12,EIF2S2,NDUFB7,HEY2,MED21,TSSC4,HSP90AA1,SRSF12,UQCC6,STK3,SNAP25,PWP2,NDUFS8,KCNJ2,MIF,BCL10,SHPRH,SSBP1,SNIP1,CDK1,PSMG4,RPL23A,FERMT2,SLU7,NUPR1,CRYAB,AGO1,KCNC1,ADD2,KCNB1,PEG10,ZNF207,RPS14,DDX42,IL2RB,ALDH1A3,PPIH,AIF1,H1-5,TIFA,RPS28,CSNK2B,TMEM126A,NEFL,COA4,H2AB1,NLRP3,H1-6,SNRPD1,TPPP3,KCTD9,RPL6,EID2,CASP4,TAFAZZIN,H2AX,TRAPPC6A,PRPF18,PSMG3,CD2BP2,TNFAIP1,LRRC8D,SDHAF1,PSMD10,DNAL1,VAMP2,KCNA3,RPF2,MED4,PPAN,TSPYL4,RBM5,USP16,CIDEB,MED11,PREB,STXBP6,PYCARD,BRIX1,GTF2A2,IL1RAP,MZB1,KCTD11,ZDHHC8,CXCL12,HFE,PFDN5,H2BC1,TESPA1,TRAF1,TRAF2,H1-1,RUVBL1,PDIA3,OIP5,ATL1,MID1IP1,SLAIN2,TRIM6,ATPAF2,SHMT1,HAUS2,CX3CL1,CAPZA1,RAF1,NDUFAF2,SF3B1,CD247,LYRM2,CD3G,MAPRE1,CALHM3,PPP2R1A,DDX46,COA5,CAPG,H2BC14,RPS5,COA1,B2M,ATAT1,DET1,CDC123,SAMM50,SRP54,CHCHD4,MKKS,SDHAF4,HOMER1,PIP4P1,RBMX2,DNAAF10,POLE3,UGDH,RPS15,LRRC8A,USP39,DLG4,ZNHIT3,GEMIN7,SRSF1,TBCE,NDUFAB1,LARGE1,RRP7A,TUBG1,MITF,COX10,SOD2,EHD1,SRPRB,DDX23,KCTD12,MDM2,TAF7,BCS1L,STK4,TP53,SLC7A9 |
| 1.685e-07 | -15.60 | CD4 (CD4 molecule) | protein interactions | 920 | 116 | 59 | 19454 | 5460 |
SELL,RPL22,GNAI2,EIF4A2,TUBB,RPS12,IL2RA,RPS9,STUB1,VDAC2,VAMP3,ENO1,HSP90AA1,ATP5F1A,CTSD,ADRB2,HSPA8,DDX5,CXCR4,MME,INPPL1,RPLP0,ABCB1,EIF2B3,SYK,UBA52,MYL12A,CD28,CD2,HSP90AB1,RPS10,MARCHF4,RPL7,KRT8,CD4,RPLP1,EEF1B2,PHB1,HNRNPD,TMEM11,CD81,HNRNPA1,EIF3D,GAPDH,PIK3R1,SIVA1,DPP4,CXCL12,SSRP1,VDAC1,CCR5,HSPD1,HNRNPA2B1,RPL18,HGS,TFRC,SPG21,CD38,RPSA |
| 1.689e-07 | -15.59 | TMPRSS11B (transmembrane serine protease 11B) | protein interactions | 132724 | 416 | 165 | 19454 | 5460 |
VDAC2,MAD2L1,CHCHD3,GNB1,ATP6AP2,ALG5,B4GAT1,LRRC8A,B4GALT3,TIMM21,RPS29,SLC1A3,GGH,ST3GAL2,VEZT,CUL2,ATP1A3,MYO6,MIA2,HADHA,CXCR4,ATP2C1,TMEM106B,XRCC5,COIL,ITGAV,STX7,EMC1,UFL1,SLC31A1,CD59,RAB6A,GLRB,TOMM22,PGRMC1,NOTCH2,SLC16A10,TOR1AIP2,CSNK1A1,EMC9,XPO5,STX5,PTK7,MPDU1,NPC2,LANCL1,GFOD1,OSBP,ASIC1,DDRGK1,PIK3R1,SLC38A7,TMEM30A,HAX1,LRRC57,FAM241B,CDK5RAP3,NCR3LG1,SLC39A3,EFNB1,PLCB1,TMEM87A,SLC25A5,NDUFA4,TMED7,RFC3,VDAC1,FAF2,TMEM59,NCSTN,ACTN4,PCDH19,ERLIN2,DIPK1A,STBD1,TAPT1,PLD3,VAMP2,STIM1,RPN1,SEC61A1,B4GALT1,SRP54,CDIPT,PELP1,NECTIN2,TECR,ROCK1,MGAT1,TMOD3,SNX3,CNNM4,HMOX2,GORASP2,ATP1A1,NRP1,XPOT,CALU,ATP1B3,GEMIN8,MTDH,SPCS2,DLAT,RAB9A,RTN4,RPA3,TEX264,ITM2B,TMEM263,TMEM209,AIF1L,FTSJ1,RABL3,SEC22B,ARHGAP1,MET,CHPF2,GALNT1,RPA2,CDCA3,SEC23A,COQ8A,PTPN1,SRPRA,ITGA6,CAMLG,LMAN1,SLC38A2,MSMO1,DNAJC1,ARL6IP5,CD151,ATP1B1,KARS1,TMEM199,CALR,ACOT8,LRFN3,DHRS7,EMC4,OSBPL8,ADGRE2,POR,STX18,ABCE1,TMX3,IGF1R,GALNT12,EMC2,STX8,RAB1A,SLC25A11,RNF167,SFXN1,ATP2B4,EDEM2,PSEN1,FKBP8,ERLEC1,CCDC47,PREB,TP53,MRPL11,TFRC,TMEM165 |
| 1.692e-07 | -15.59 | MCL1 (MCL1 apoptosis regulator, BCL2 family member) | protein interactions | 4170 | 129 | 64 | 19454 | 5460 |
UBXN6,BAK1,EDEM1,VCPIP1,BCL2L1,TRAF6,BECN1,IL10,MCL1,YBEY,TNKS,BOK,HRAS,IER3,EGLN3,CAV1,SPPL3,FZR1,MAPK10,TP53,MLLT11,KCNF1,JOSD1,PRKAG1,PCNA,TRIM11,STX8,EDEM2,RIGI,KRAS,HUWE1,VDAC1,BAG3,MYC,USP13,HSP90AA1,BAX,RIT1,SERPINH1,H1-1,FBXW11,GSK3A,EDNRA,BAD,CHRM4,CDC20,APEX1,RANBP6,CPT2,DYNLL1,DUSP22,PRKAB1,TPT1,CDK1,HSPA8,PMAIP1,EP300,SQSTM1,PEBP1,DAD1,SLC5A6,SKP1,FBXW7,NSFL1C |
| 1.705e-07 | -15.58 | PRPF6 (pre-mRNA processing factor 6) | protein interactions | 24148 | 310 | 129 | 19454 | 5460 |
SF3B4,SNRPD2,SMU1,SNRPD1,DLST,SNRPB2,MATR3,FBXO22,SNRNP40,BTF3,PRPF31,SNRPB,MYC,CUL3,FHIT,RIT1,BRCA1,HSPA8,SF3B1,EP300,DDX39B,SNRPA,CXCR4,SNRK,SAP18,COIL,EMC1,UFL1,SRSF2,FXR2,RFXANK,WDR77,PIH1D1,CTBP1,USP39,EMC9,EED,LSM5,SUMO2,SNRPA1,SNRPD3,CTNNB1,TRA2A,DDRGK1,PRPF19,WWP2,YWHAB,DDX23,EWSR1,RPS24,RTCB,SRSF7,MRPS11,SRSF8,RPL31,SSRP1,AHCYL1,KRAS,NCSTN,TRMT1L,RAF1,TPBG,E2F4,SNRPE,EZH2,HDAC11,NME1,PDHA1,CCNF,ZNF330,CTTN,GCFC2,EIF4A3,VIRMA,SRPK2,DEPDC1B,AR,UBE2H,BICD2,LSM6,PGK1,RNF113A,RPA3,BAP1,PRPF4,TRIM3,PML,LGI1,SIRT7,IDH3A,VPS28,FBXW7,RBM22,CFTR,SF3A1,TXNL4A,SNRPN,HEXIM1,TFIP11,RPA2,LMNA,LSM2,ZNF326,RCHY1,RBM42,CDC5L,FZR1,TOP1,THOC1,LSM3,IL17F,H2AC4,SNRNP70,KIAA1143,HAPSTR1,SNIP1,MEPCE,RPS13,SNRPG,TSSC4,LSM4,SNRNP48,PSMA5,THRAP3,CD2BP2,EXOSC8,TP53,NUPR1,IK |
| 1.742e-07 | -15.56 | macromolecule biosynthetic process | biological process | GO:0009059 | 3197 | 1063 | 18204 | 5365 |
SYNCRIP,NGDN,CREBL2,TIA1,ESS2,RWDD1,INHA,MRPL22,METTL2A,RPS2,EEF1G,RBFOX3,ECD,PHKG1,ENPEP,WDR82,ELP6,EIF4E3,HSPA13,LYAR,SNAPC3,ELK1,RPS23,MED29,KHDC4,HYPK,SRSF10,RPLP0,LIG3,H3C1,RPLP1,RMND1,POLR3F,BAP1,SNAPIN,RPL26L1,MPHOSPH10,MRPS7,AURKAIP1,HSPD1,HAS3,ST13,OSGEPL1,RPL39,THUMPD1,GAL3ST4,MRPL11,EEF1A1,LUC7L3,RPS17,POLR3B,RNASEL,DUOXA2,SNRPB2,RNF14,THRAP3,STOML2,ASMT,VIRMA,ERP29,GTF2F1,POLL,EIF2AK2,MRPS18B,RIOK2,RIC3,RRN3,TRIM24,GYS1,ATG4C,CDK12,GALNT17,TSR2,TSPAN15,INTS6L,MED31,CHPF,DDX39A,JAK2,BAD,UGCG,TUBA1A,ABCE1,B4GALT7,KPNA6,POLR1D,EIF3G,NOP53,MRPS35,AKAP17A,GON7,DPH3,MRPS34,GRB10,SMAD4,ISG20,LSM4,PDIA2,PRMT5,RPS27A,RPN1,WDR77,NAA16,CSTF3,EIF3D,KARS1,POP7,HSD17B10,EP300,DR1,RPSA,GEMIN8,RFC3,MAGOH,TSNAX,TMEM106A,CYFIP2,SLC1A1,CRTAP,RPF1,CTNNB1,SHLD1,IRF1,SLC30A5,DTWD2,PQBP1,DNAJC5,TMEM208,MAN1A2,PIGK,C1GALT1C1,UTP15,GTF2IRD1,ALYREF,KRR1,EIF3K,MGAT1,HS3ST3A1,EIF1AD,METTL14,EIF2B5,NBN,RPP25,RPS24,IFI16,PGK1,CCT5,TFIP11,SNAPC2,GOLGA7,UBL5,MECP2,SMARCB1,NOB1,IVNS1ABP,B4GALT4,DNAJB4,GCNT3,MRPL50,PDIA6,SRSF4,CELF6,EXOSC3,ADGRG1,BMPR2,DRAP1,SRC,PPIL3,ANGPT1,SERPINH1,PIWIL3,SMARCA5,PPID,EIF1B,CSTF2T,GXYLT2,PTGES3,EXT1,NRDE2,SRGN,MGAT4B,ATF4,NOVA1,POLR2F,SNRPB,HNRNPK,SQSTM1,POLR2G,SF3B6,ISCA2,METTL6,TCOF1,PSEN2,CHPF2,MRPL51,FAU,RBM27,MED17,GALNT1,TENT2,ZRANB2,DTL,RPL8,CPSF1,DHX38,MEF2A,MRPL53,ELOF1,PRKRA,CSGALNACT2,NAA11,FKTN,DNLZ,NDP,THBD,TTC1,CD2AP,TSR3,ZDHHC16,MRPL24,FAM20B,DNAJC7,TMEM59,GRM2,UTP23,TXNL4A,RPAP2,SNRPD2,HNRNPF,MRPL18,TFCP2,CLPX,BMPR1B,PRSS37,UGP2,RPL32,PRSS12,FOS,P3H1,LIPT2,MRPL33,PABPC1,SUPT3H,MGAT4A,MRPL20,EIF2S1,RPL24,B3GNT2,FUT9,GTF2E2,TERT,KCNJ8,HS3ST1,NFKB1,WDR83,RPL19,RPL3,MED30,CLU,ZDHHC4,GRPEL1,TYW3,SNRNP27,ELP3,DNAJC4,PKNOX1,RPS7,TRMT1L,EIF1AX,SMAD3,GPAA1,ATG4A,ATG16L1,CMTR1,ELOC,SELENOK,NXT2,TAF9,SNRPN,POLD2,HNRNPD,EIF4A3,SMAD2,TAF2,BUD31,ALKBH5,RBM22,ZCRB1,IRF9,MPHOSPH6,ZMPSTE24,RNF113A,ARB2A,RPS27L,MRPS21,PSEN1,EGR2,SNRPG,SNRPA,APOBEC3F,MRPS23,WBP11,YBEY,SNRNP70,POLR2I,FCF1,RBFOX2,SMG5,NDST3,MRPS33,MTG1,PFDN6,PRDX4,ST3GAL1,POLR3H,RPP14,NAA60,FKBP1B,CDKN2D,CD28,CBFB,HSP90AB1,OST4,SNIP1,ATP6AP2,POLR2D,WDR45,NAA50,PWP2,DAD1,EIF2S2,POLR3GL,HSP90AA1,NFIL3,MED21,USP15,PMPCA,MRPS26,THOC2,MRPL16,HNRNPA1,WWP2,MRPS28,DNAJC19,SPON1,SLU7,HSPB2,MARS1,HSPB1,SCNM1,TDRD7,SELENOF,RPL23A,TYW5,ACTMAP,CREB1,MRPL9,MTF1,CWF19L1,AIP,PRCP,CDK7,MRPL36,HSPE1,CISD1,COIL,MACROH2A1,SMAD1,CCT2,PFDN2,COPS5,SNRPA1,SNRPE,METTL25B,HNRNPC,FOSL2,AHSA1,WDR3,EIF2D,PXYLP1,EIF3J,QNG1,NPM3,TTC4,NFKBIB,GAL3ST1,CREBBP,PROX1,RPL22,ZDHHC24,RTCB,FARSA,PIWIL2,MPDU1,RP9,PPP1R3C,DTWD1,GTF2H5,MRPL40,METAP1,SRPK2,KRAS,SNRPD3,DPY30,POLB,TCEANC2,IL2RG,DRG2,RPP21,TWNK,PCNA,SNAPC1,GOLGA7B,GLE1,SPCS2,CCNA2,B4GALT6,RPL23,LIPA,ST8SIA4,POLE4,PPARG,MYRF,IKBKB,CHCHD4,EGR1,MKKS,LSM6,POLR2L,MNAT1,NR4A2,EPO,PTGDS,AASDHPPT,MRPL47,RPS20,EDEM3,RPS5,NCSTN,EIF4H,RRP7A,PIWIL4,FGFR1,SRSF1,ATXN1L,CMTR2,HELT,NDUFAB1,COMT,PSENEN,TBCE,UGDH,POLE3,NONO,DNAJC2,MRPS18A,DDIT3,TSEN54,FKBP10,SEC11A,POLR1B,ERCC3,SPPL3,FKBP8,NOP9,PFDN1,CHST10,ABCC5,TAF7,PGAP4,VPS72,ZMAT5,EIF4E2,RPS16,LDB1,LMAN1,DIS3L,MTRES1,KTI12,SCN2B,WDR83OS,RPS28,HSD17B1,PPIH,POMT2,BOLA2B,HSP90B1,SPHK2,PPAN,INPPL1,EEF1B2,RPF2,TSEN34,FRA10AC1,QRSL1,ANKH,TFB1M,OGG1,TRA2B,SPCS1,PIR,KLK6,H2BC1,RPS29,ZDHHC8,DFFA,MME,BRIX1,PRPF4,DPAGT1,CD226,CARS1,BATF,HNRNPH3,GTPBP1,S100A10,SRSF2,SRSF8,GALNT2,ZC3H15,NAA15,POLDIP3,ADIPOQ,ETF1,PPP1R1B,EEF2,RPS3,MSX1,RPL10,ATG7,HDAC3,SRD5A3,CDC73,B3GALNT1,RBM34,DNAJB2,B3GALT4,ST3GAL2,RAMAC,DNAJC3,DHX16,HM13,DNAJB6,AQP11,EDNRA,RPL27A,WNT10B,MAD2L2,GFPT1,URM1,RIGI,PAX6,PAPOLA,NUS1,SLC35C1,MED27,GTF2A1,TUFM,NCAPG2,RPL7A,TAPBP,EXOSC1,PIGW,FOXP3,RCL1,FUT1,ERRFI1,DHPS,RPLP2,AKT2,HS3ST5,COPS2,TENT4A,SMN1,DUS4L,RPL12,CLIP3,SF3B4,POLR2C,DDX1,MMP14,ZDHHC14,DNTT,POLD4,IMMP2L,POP5,NKX3-2,THOC6,PAIP1,LSM5,DDX39B,NOP58,PADI2,ADAT1,EIF4E,TRAF3IP2,HEXA,GP9,NDST1,IL6,UTP6,XBP1,TSPAN5,RPL13A,RPL27,PFDN4,EIF4A2,CPE,TERC,DOLK,AR,MRPL52,SOD1,SNAPC5,PAIP2,HIRA,IL2,MSH6,CYTL1,NR1H2,B4GALT1,FTSJ3,PCSK9,TAF11,PPP5C,RPL4,RPRD1A,PARL,DIO2,SMU1,B3GALT2,SRFBP1,GLCE,DOHH,AKT1,BMP1,IL1B,ELAVL4,CEBPE,KBTBD2,CLP1,PDRG1,CCT7,DNAJC24,RPL26,FKRP,EIF4B,SLAMF9,RPS4X,METTL15,MTERF2,UBA52,FUBP3,EXOSC8,GRSF1,CHCHD1,SIRT7,SKIC8,CALR,DKC1,APH1A,IGF1,MRPL23,WTAP,ENY2,B4GAT1,NUDCD3,VDR,BAK1,CTNNBL1,CPSF2,PIK3R1,CCDC47,ST3GAL5,CUL3,MRPL49,STT3A,CDC40,TRUB1,DEK,HS2ST1,TCP1,CAPN2,NIBAN2,PIGY,EIF3E,MRPL41,RCE1,BCL9,RRM1,GTPBP2,PPM1B,UNC45A,HSPB6,RPS12,GTF2E1,RPS11,SAMHD1,GTF3C4,RPL31,WRAP53,TOR2A,GTF2H2,CHST1,CHTOP,HNRNPA2B1,RBM41,CD40LG,TRMT11,UTP25,BACE1,RPL35A,CHST13,RBMS2,NUP107,APEX1,F7,WDR12,TAF10,ADRM1,MAGOHB,WDR55,RPS10,THOC1,GFM2,SUPT4H1,RPS13,MRPS25,PRPF31,FKBP4,ST8SIA5,TBCEL,APOBEC3A,MRPL12,C1D,MRPS9,CCNH,MRPL13,GTDC1,TRMT6,PPIF,DPP4,YIPF5,TRMT10B,VPS54,AKAP8L,RPL7L1,DNAJC1,POLR2B,EIF5B,RBM42,KIN,WBP2,RPL10A,NPPC,GLRX5,MGAT5B,MRTO4,GCFC2,EXTL2,PIH1D1,PIGA,MED10,SCG5,HNRNPL,ARFGEF1,NOC4L,MAK16,PPIC,APOBEC3C,ZC3H11A,CCAR2,SELENOT,MED22,FOXA3,POLDIP2,SGF29,MRPL17,ZDHHC17,DPM2,TESC,INTS12,EAF2,NOL7,TCEA1,XPO1,RBM17,VSIR,APEH,MED23,NPC2,MRM2,CNOT6L,TRMT112,GLUL,MRPS18C,MED9,MYD88,GTF2H4,TAF5L,HTRA2,KLHL3,THAP1,HSPA5,PAAF1,CDC37L1,RPL37A,DGCR8,FXN,LSM10,RPL10L,MRPL57,FAM98A,F9,RPL17,FURIN,RPL18,SNRNP48,EEF1E1,FASTKD5,THG1L,TRMO,GPBP1L1,ALG5,YAE1,RUVBL2,SWAP70,RPS9,MRPS16,CMA1,REN,PMM2,PCSK2,EIF5A2,NXT1,OSGEP,SRSF12,GTF2F2,TSSC4,UST,BARX2,GBE1,DDX42,TLR3,RPS14,PELP1,ZDHHC15,SREK1IP1,TUSC3,PPIA,CRYAB,PGAP3,AGO1,SECISBP2L,IFT172,RCHY1,RTRAF,ARMC7,ERO1A,PPIG,PDF,BAG3,SART3,ALG11,MRPS17,SOX9,CPSF4,IL1R2,NSA2,HNRNPA0,CSNK2A1,EXOSC4,CPEB1,RPL7,SUB1,QTRT2,MTRF1,LSM8,RBM23,CHST11,SF3B5,DNAJC25,GXYLT1,IMP4,TOPORS,CWC15,POLA2,DICER1,CDC5L,PELO,PRPF19,DHX15,NHP2,XXYLT1,TSN,EIF4EBP2,BUD23,FKBP1A,CTU1,HSPA14,DRG1,CCS,DHX9,SDF2L1,RPP25L,DBR1,COL3A1,FKBP2,CHRAC1,PRDM4,DDX4,ADRB2,ZNF345,SRSF7,ZNHIT6,CCR6,SF3A1,GALNT4,THOC3,STAT6,RNF8,GTF2B,ST6GALNAC3,GFM1,CHST9,EIF2B3,SMNDC1,RPL29,LTO1,LSM2,RPRD1B,PGAP2,LTB,TRMT5,ZMAT2,AANAT,SUGP1,B4GALT3,DDX46,NAA35,SUV39H1,FYTTD1,MRPL10,TRA2A,PPWD1,ALG2,SNRNP40,RPL15,GMPPB,RBM15B,TRMT61A,RBM3,MLF1,GAPT,CDC123,LGALS3,METAP2,WDR6,HMCES,PRIM2,EIF2B2,GTF2I,TCEA2,DROSHA,PIWIL1,RPS26,ZNF326,B2M,BAG2,INTS10,LARGE1,HSPA8,PPIB,RPL9,GEMIN7,ITGAV,CHORDC1,ZNHIT3,SAP18,ZNF473,TRIP4,EMG1,POLR1H,TMEM165,USP39,IMP3,MRPS11,RPS15,TLR4,RARS1,B3GALT1,ST3GAL4,KLF4,RBMX2,TOR1B,CIAO1,SPCS3,MAEL,TP53,ST6GAL1,DDX23,HENMT1,PIGC,TRMT13,DDX5,NCBP2,FTSJ1,RPL35,ZC3H7A,CSGALNACT1,EPOP,NLRP3,GTF3C3,CEBPG,BOLA3,RBM38,CNTN1,SNRPD1,CHST2,RP2,H2AB1,GALNT12,CHST7,CASC3,FUT8,MFAP1,NHEJ1,ABCF1,RBM5,CDK9,SUPT5H,NFYA,MED4,LSM3,CD2BP2,RSRC1,TYMS,RB1,IK,CASP4,RPL6,PRPF18,PFDN5,RSL24D1,PLAC8,BCL6,RPL28,STUB1,SSU72,DNAJC10,CCT8,GTF2A2,MED11,PCLAF,MRPL34,HINFP,SF3B1,GRPEL2,TNF,PDE12,PDIA3,PHB1,TEX12 |
| 1.748e-07 | -15.56 | Degradation of DVL | REACTOME pathways | R-HSA-4641258 | 59 | 38 | 10285 | 3229 |
PSMC1,CUL3,PSMC4,PSMD12,PSMB5,PSMA3,PSMB1,DVL2,PSMB7,PSMD3,PSMA6,PSMB3,PSMA2,PSMB6,PSMD1,PSMB2,PSMA5,PSMB10,PSMC5,PSMB11,PSMA4,PSMD7,SEM1,PSMB9,PSMB4,PSME1,PSMD6,PSMD10,PSME2,HECW1,UBB,PSMD4,RPS27A,UBA52,PSMA1,KLHL12,PSMC3,PSMD14 |
| 1.752e-07 | -15.56 | FFAR1 (free fatty acid receptor 1) | protein interactions | 2864 | 230 | 101 | 19454 | 5460 |
ATP1A3,COX6B1,PARL,TNPO3,NDUFAF4,SLC30A7,GGT7,RMDN3,FDFT1,MTX2,TOMM22,YIPF5,RER1,ATAD1,CMTM6,TMEM160,ATP2C1,RAB5A,SLC20A1,PEX3,SLC25A21,SYNJ2BP,FAM20B,WDR11,ADCK1,ECHDC1,RMND1,MPDU1,KDELR1,PTRH2,GNAQ,TMT1B,YIPF3,ARL5B,RAB18,SACM1L,NDUFB5,PLSCR1,JAK1,ENDOD1,GGCX,RETSAT,HMOX2,YES1,SLC25A4,MGST3,RAB14,VKORC1L1,UQCRQ,CDIPT,SLC1A1,SFXN2,CHCHD6,SAMM50,GHITM,STX17,SLC12A2,GALNT1,SDCBP,COX6C,TIMMDC1,COQ8B,GABARAPL2,KDELR2,ABCC2,TMEM209,UQCC3,TMEM263,RAB29,NDUFC2,RAB9A,DERL1,TMEM70,RAB3A,SLC25A46,TMBIM6,DERL2,EIF2B5,SPPL3,MSMO1,NDUFB4,COX4I1,GNPAT,LDLR,XXYLT1,C2CD2,DECR2,TMEM165,DHRS7B,IPO8,TMEM126A,CCDC47,AGPAT5,MAP2K3,RAB3B,LPCAT3,FASTKD5,ATP2B4,DDR1,RUSF1,RAB13 |
| 1.772e-07 | -15.55 | regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001236 | 157 | 77 | 18204 | 5365 |
RAF1,ICAM1,IL1A,STK4,CX3CL1,IGF1,PEA15,TNF,TNFSF10,PDIA3,MIR142,GPX1,TRAF1,ITGA6,LTB,TNFAIP3,FGF10,DBH,HYAL2,GSTP1,SFRP1,TRAF2,SRC,SCG2,BCL10,AKT1,IL1B,SIAH2,FEM1B,PELI3,TNFSF12,FAIM,LMNA,ITGAV,ZMYND11,GCLC,FGFR1,PRDX2,RB1CC1,TMBIM1,PYCARD,RNF34,PAK5,STK3,IFI6,TLR4,EYA3,ATF3,CSF2,TLR6,PML,RBCK1,NRP1,LGALS3,BCL2L1,BMPR1B,CAV1,G0S2,IL7,STRADB,CTTN,MIR198,FAF1,PMAIP1,TERT,PPP2R1A,CTNNA1,MCL1,MIR222,ACVR1,BRCA1,HTRA2,AR,SNAI2,PAK2,MIR221,LTBR |
| 1.775e-07 | -15.54 | KIF5B (kinesin family member 5B) | protein interactions | 3799 | 316 | 131 | 19454 | 5460 |
TUBA1A,PPP2R1A,MOB3C,PDHA1,EZH2,RUVBL2,RPAP3,PABPC1,CCT8,TFG,PSMD12,VDAC1,PSMA2,HNRNPF,EXOC1,CTNNB1,YWHAG,INSYN1,PPIB,YWHAH,PSMD3,PRPF19,PIK3R1,IFI16,YWHAB,MED4,LBX1,PSMD10,AZIN1,PSMB5,PSMB4,DHX15,EGLN3,DYNC1I2,SUMO2,RPS10,NEK7,PPP1CB,PSMB3,NUP62,KLC2,EIF4B,RNF7,PSMB7,NUP50,EP300,HSPA8,XRCC5,MCMBP,STAU1,MCM3,PSMD1,CUL2,PSMA4,RUSC2,RAB11A,SFN,CUL3,MYC,YWHAZ,PSMD14,BRCA1,GCC1,AP1G2,SYBU,PRMT5,DLST,LMBR1L,ESR2,PSMB6,PSMD6,SYNE4,TSN,TAX1BP1,PSMD4,TP53,CASK,PSMC3,POLR2G,DHX9,SNAP23,ABCE1,PSME1,PALM2AKAP2,CAPZA1,RNF20,MEPCE,HUWE1,PSMA5,TPM3,COPS5,NFKB1,MAP4,TSNAX,PSMD7,NME2,TRAK2,PTPN1,CD274,CDC5L,MYL12A,CDK9,SNAP25,CFTR,ACACA,PRKCA,CDR2,HEXIM1,METTL14,LSM2,RPA2,SQSTM1,PML,SIRT7,PRPF4,BAP1,SOD1,RPA3,HSPA5,KDM1A,SGF29,ST13,UBE2H,POU1F1,RPS20,PSMC5,CCNF,VIRMA,HOMER1,ADRM1,COPE |
| 1.796e-07 | -15.53 | protein folding | biological process | GO:0006457 | 215 | 99 | 18204 | 5365 |
LMAN1,RP2,TTC1,CSNK2A1,PFDN4,WDR83OS,DNAJC7,ERO1A,BAG3,PPIG,FKBP4,AIP,TBCEL,DNLZ,PPIH,RIC3,HSPE1,DNAJC25,PPIF,CCT2,NPPC,PFDN2,CLPX,FKBP1A,HSP90B1,DNAJC1,HSPA14,AHSA1,P3H1,CLU,FKBP2,DNAJC10,DFFA,SDF2L1,PFDN5,TTC4,PDIA2,DNAJC4,MPDU1,DNAJC24,PPIC,PDRG1,CCT7,CCT8,GRPEL1,GRPEL2,CALR,NUDCD3,CRTAP,PDIA3,CCDC47,HSPA5,CDC37L1,DNAJC5,TCP1,CCT5,DNAJB6,DNAJB2,DNAJC3,HSPA13,CDC123,HSPB6,UNC45A,PFDN6,PRDX4,DNAJB4,CHCHD4,MKKS,FKBP1B,B2M,TAPBP,HSP90AB1,HYPK,PDIA6,RUVBL2,PTGES3,CHORDC1,TBCE,PPIL3,BAG2,HSPD1,HSPA8,PPID,PPIB,TOR2A,TOR1B,HSP90AA1,DNAJC2,ST13,FKBP10,PFDN1,DNAJC19,FKBP8,SELENOF,ERP29,PPIA,HSPB2,CRYAB,HSPB1 |
| 1.834e-07 | -15.51 | MRPS30 (mitochondrial ribosomal protein S30) | protein interactions | 10884 | 205 | 92 | 19454 | 5460 |
SRSF4,MRPS17,HSPD1,LSM14A,HINT2,VPS26B,RAF1,HNRNPL,GATD3,FAHD1,RHOG,MRPL18,SKIC8,MRPS26,HNRNPD,ARMC8,MTRF1,RPL6,HNRNPA1,MRPL9,HSCB,RER1,MRPL57,NGRN,EXD2,MRPL34,MRPS18A,SLC25A3,RPL27A,MRPL12,MRPL23,RPL35,RPL19,RPL10,PRRC2A,TACO1,CCDC90B,MTG1,RPS9,MRPL13,RIT1,AUH,MTG2,PMPCA,MRPL16,FASTKD5,MRPL22,MEPCE,RPL17,MRPL52,RPL23A,GFM2,MRPL33,MRPL51,MRPL49,MRPL11,MRPL47,AURKAIP1,METTL15,MRPL50,PRNP,MALSU1,MRPL24,SSBP1,SNRNP70,TMEM70,GRSF1,RBFOX3,MRPL17,YKT6,MRPL40,MRPL41,MRPL20,UTP23,SNAPC1,RPA3,PGK1,GFM1,RPA2,RPL26L1,MTRES1,NDUFAB1,MRPL10,CFTR,RBMS2,RPL13A,MRPL53,IGF2BP1,UBE2H,ZMYND19,RPL26,TUFM |
| 1.842e-07 | -15.51 | positive regulation of cell motility | biological process | GO:2000147 | 619 | 241 | 18204 | 5365 |
MIR448,TWIST2,MIR10B,CCR1,PRKCE,ACTN4,FGF1,TIRAP,NRP1,ATP8A1,JAK2,CD151,CRKL,SNAI2,TGFBR2,PLAA,MIR221,GNAI2,SOX9,KIT,XBP1,MET,MIR20A,CCL21,TF,ADAMTS1,CCL24,DEFB1,FGF10,TCAF2,ATP5F1B,IL1A,PIK3R3,MAP2K3,TGFB2,CALR,IGF1,PDCD10,ACTA2,TNFSF18,PROX1,CCL20,CFAP20,ITGA2,SEMA3C,CCR6,SEMA5A,CDH13,CCR7,AKT1,IL1B,MIR182,FAM107A,PPP3CA,WNT7A,MIR150,NUS1,MSTN,SWAP70,MIR210,CAV1,PAX6,PTN,HBEGF,MIR21,FGFBP1,MIR146A,MIR519D,UBE2I,S100A11,CLDN1,SEMA4C,ELP6,MIR342,TACR1,MIR31,CD99L2,GLIPR2,IL4,MIR208A,HSPA5,RTN4,SEMA6C,CDC42,MMP9,HSPB1,FERMT2,CCL17,MIR126,IGF1R,IL6,FGR,AKAP12,DEFB124,EPHA4,MIR200A,DUOXA2,MMP14,FOXP1,GPSM3,CCL5,EMC10,DAPK3,VEGFC,MIR10A,CSF2,OXSR1,IQSEC1,CD274,FAM89B,IL12A,AKT3,MIR132,FUT1,AKT2,CCL3,ATP5F1A,CCL4L1,PLP1,CCL18,DRD1,TERT,TMSB4X,CXCL10,TNFRSF14,CCL2,MIEN1,STAT5A,ARF6,CLDN3,CCR2,FOXC2,CCL19,AIF1,CCDC25,CCL25,RARRES2,CYP1B1,ACVR1,MIR222,MIR181D,PRKCA,MED23,RAB11A,SELENOK,TRIM32,CX3CR1,MIR145,SMAD3,CX3CL1,MIR101-1,ROCK2,XCL1,DDRGK1,VSIR,TNF,PYCARD,HRAS,MIR23A,PLG,ZNF304,CREB3,GFUS,AGER,RHOB,TBC1D24,HDAC6,ELP3,CXCR4,ACVR1B,CLDN4,EPHA2,BCL6,CXCL12,CD40,CCL23,FGF7,HMGB1,MAPRE2,FGF16,MIR29A,CCAR1,BMPR2,IL23A,VEGFA,SEMA7A,IL34,LGALS3,NFE2L2,F10,MIR30A,SP1,MIR296,NTRK3,CXCL13,FZD4,MIR711,GPNMB,CCL1,AAMP,RHOJ,PIK3R1,GAB1,TACR3,SOD2,MIR135B,MIR143,P2RY12,ITGA6,TNFAIP6,CLEC7A,MAP3K3,ICAM1,STK4,IFNG,MADCAM1,RRAS2,ARHGAP5,SDCBP,F7,CD47,TIAM1,LPAR1,MDM2,CXCL8,THY1,PIK3CG,MIR939,TLR4,CCL11,CBLL1,ARHGEF39,MIR590,CCL8,SRC,ANGPT1,ZNF609,FGFR1,ACKR3,ITGAV,RAC2 |
| 1.861e-07 | -15.50 | CMPK1 (cytidine/uridine monophosphate kinase 1) | protein interactions | 51727 | 106 | 55 | 19454 | 5460 |
OXCT1,GPC1,HSCB,POLDIP2,GRPEL1,RHOU,RPA3,EP300,STX17,GSTP1,DDAH1,SPR,STXBP1,NEK7,NDUFAB1,CDC42,RND2,RHOJ,CLIC4,SUCLG2,EIF2AK2,TRIM23,RHOB,GLOD4,RIT1,UBE2H,NRP1,ACO2,ATP5F1A,ETFA,KRAS,MPST,BACE1,HINT2,PDHA1,ACOT13,GDI2,EZH2,FURIN,FEN1,RRM1,PGM1,GLRX5,SOX2,MAP1LC3B,RHOH,AK5,NUP35,CAV1,HDHD3,GATD3,LCMT1,AGR2,CIDEB,MOV10 |
| 1.873e-07 | -15.49 | DDB1 (damage specific DNA binding protein 1) | protein interactions | 1642 | 614 | 230 | 19454 | 5460 |
ARGLU1,PCNA,RBBP7,LASP1,SSRP1,COPS4,RAD21,PSMD12,RAF1,ZNF263,SAP30,FAF2,PPP2R1A,CHMP4C,EZH2,PHB1,COPS2,SNX2,COPS7B,LRWD1,CGGBP1,EGLN3,HMGA1,PSMD3,DYRK1B,WDR11,TRAF6,PSMD10,SKIC8,DDX23,HAX1,DCAF11,CDKN1B,TERT,HADHA,CMAS,TOR1AIP2,WDR77,KCND3,LMO4,DET1,CDKN1A,SUPT3H,RNF7,RSRC1,RBBP4,DYNLL1,TUBB,ACTB,IP6K1,CLIC4,CUL3,SAMHD1,RNF40,DCAF4,BRCA1,MYO6,ILK,RAB1A,RING1,HUWE1,PPDPF,MTA3,EEF1A1,MAP2K3,RCHY1,AIFM1,PTPN1,H2AZ1,PSMB1,PRNP,DCUN1D1,ZBTB2,MDM2,TLE1,SUV39H1,CRBN,TOPBP1,DNAJC7,PRPF4,SIRT7,RPA3,HELLS,RTN4,FBXW7,NUCKS1,NF2,DGCR8,MEF2A,MBD3,ATG16L1,SAP30BP,LSM2,METTL14,OXSR1,VAMP3,CCNF,ALB,PTEN,ACAT1,VIRMA,TECR,USP14,BRAP,DCAF16,PABPC1,BCL9,RUVBL2,EWSR1,HNRNPF,KRAS,PSMA1,PAK6,CCAR1,DHX38,RPS7,SOX2,ISG15,DCAF8L2,MOB3C,DCUN1D5,MTA2,SIN3A,GNB3,EED,DYNC1I2,ELK1,DCAF4L2,CNOT2,CTNNB1,DDRGK1,AGR2,DCAF5,POU5F1,CBL,FOS,XRCC5,EP300,HSPA8,HDAC5,ARHGEF39,EEF1G,UFL1,FBXO42,PPT1,NCOA5,PIH1D1,CNDP2,DDIT4,PRMT5,SMU1,FBXO22,SNRNP40,PSMD6,MATR3,STAT1,ESR2,APEX1,PSMB6,PPP5C,CBX5,COPS7A,MYC,MLF2,PSMD1,FTSJ3,PSMD14,TRIB1,H1-1,COP1,MAP1B,H3C1,NEDD8,PHF1,MEPCE,TP53,MTCH2,H2AX,CBX3,RNF8,NUPR1,CD274,MIF,CAND1,SPPL3,FZR1,CDC5L,ELOC,COPS5,CSNK2A1,SNRNP70,BECN1,SHC1,H2AC4,USP15,MAP4,CDK12,BANF1,BAP1,RNF113A,DERL1,HDAC3,RGS2,HSPA5,WSB1,CFTR,AGO1,WWP1,RPA2,RAG1,LUC7L3,HEXIM1,DYRK2,TFIP11,UBE2M,PSMA6,DCLRE1C,MACROH2A1,PSMC5,ADRM1,BUB3,NR1I2,SUB1,SMARCA5,FBXO44,UBE2E3,KCNMA1,UBE2H,DTL,ZBTB38 |
| 1.895e-07 | -15.48 | endopeptidase complex | cellular component | GO:1905369 | 86 | 48 | 19108 | 5553 |
RAD23B,PSMB1,PSMB11,PSMA6,ZFAND2A,GPAA1,PSMC5,PAAF1,PSMA3,PSMA1,CAPN1,CAPN2,PSMB7,ZFAND2B,PSMD7,TXNL1,PSMD14,HSPB1,PSMB5,PSMA5,PSMB9,PSMB2,PSMD3,UBE3A,PSMA2,PSMB4,PSMB6,MBL2,PSMA4,PSMD12,USP14,PSMD4,ADRM1,PSMD1,PSMB3,PSMD10,PSMD6,FCN2,PSME1,CRADD,PIGK,PSMC3,PSMC4,PSME2,PSMB10,THBD,PSMC1,HTRA2 |
| 1.906e-07 | -15.47 | negative regulation of endothelial cell proliferation | biological process | GO:0001937 | 78 | 45 | 18204 | 5365 |
SYNJ2BP,MIR126,MIR34A,MIR15A,MIR133B,TNF,PDCD10,MIR24-1,IL12B,MIR98,MIR152,KRIT1,MIR361,MIR495,MIR205,PRL,VASH1,ATP5F1A,MIR132,SCG2,IL12A,MIR16-1,MIR129-1,MIR424,MEF2C,MIR29C,CAV1,CCL2,STAT1,CAV2,MIR149,ATP5IF1,MIR503,PPARG,MIR21,MIR30B,MIR497,MIR146A,MIR492,MIR193A,GHRL,MIR342,MIR222,RGCC,MIR30E |
| 1.919e-07 | -15.47 | PSMG1 (proteasome assembly chaperone 1) | protein interactions | 8624 | 101 | 53 | 19454 | 5460 |
PSMC3,CAPZA2,PSMB9,RAF1,ACO1,UBE2A,CA10,CAPZA1,PSMA2,SEM1,PSMA5,PSMA1,KRAS,HSPD1,EHD4,BRD3,PSMG2,SNRNP70,PSMD3,SPTAN1,SEC23A,PSMB1,AIFM1,PSMB4,RPA2,PSMB7,SOST,CDK7,PSMC4,FAM89B,PSMB3,PSMC1,PAFAH1B2,PSMG4,PSMA3,RPA3,PSMG3,RIT1,POMP,BRCA1,CCDC22,PSMD1,BAG3,PSMB2,PSMA4,HNRNPC,PSMB6,APEX1,PSMD4,PSMD6,RTRAF,PSMC5,PSMA6 |
| 1.921e-07 | -15.47 | PRDX6 (peroxiredoxin 6) | protein interactions | 9588 | 236 | 103 | 19454 | 5460 |
HDAC6,GLO1,EMC4,AKR1B1,SDHB,SSU72,COX4I1,GLRX5,H2AX,PGM1,FBP1,TP53,FURIN,TFCP2,HINT1,HSD17B10,HUWE1,MTPN,SFTPA1,CSK,ATP1A1,FXN,UBE2H,PPTC7,CCNF,ENO1,SUCLG2,VIRMA,LDHA,NDUFAB1,CD2AP,CDK7,CFTR,SPR,UBE2M,GSTP1,RPA2,LMNA,IDH2,PRDX6,GPX4,BAP1,SOD1,RPA3,CRYZ,BCL6,DDRGK1,PRDX1,AHSA1,NQO1,HSPB1,GSTO1,PEDS1,AGR2,TRAF6,GATD3,ATP6V1A,FOLR1,PHB1,HNRNPL,SUMO2,ISG15,SOX2,LYPLA1,RAF1,E2F4,EZH2,NME1,RAB4A,CHMP4C,SCPEP1,PCNA,HINT2,GUK1,G3BP1,VDAC1,CAPG,MYC,ACO2,CUL3,PMPCA,MDH1,APEX1,CLIC4,ESR2,PRDX2,TAGLN2,TENT5C,NEK7,LAP3,PIH1D1,ARCN1,MAP2K1,HDAC5,HSPA8,TXNL1,PMAIP1,PTRHD1,ASB3,EMC1,UFL1,OXCT1,STAU1 |
| 1.941e-07 | -15.45 | positive regulation of tissue remodeling | biological process | GO:0034105 | 23 | 19 | 18204 | 5365 |
MIR34C,IL12B,ROCK2,MIR34B,IL18,MIR20A,MIR214,PPP3CA,MIR17,IL15,MIR34A,TMBIM1,MIR143,MIR195,IL23A,ROCK1,MIR16-1,IL2,IL21 |
| 1.947e-07 | -15.45 | positive regulation of defense response | biological process | GO:0031349 | 430 | 176 | 18204 | 5365 |
TLR2,TRAF6,NLRP3,TLR10,TICAM2,PLSCR1,TBK1,XRCC5,NINJ1,MAPKAPK3,TMEM126A,TLR5,TIFA,CCR2,PDE2A,MAP2K6,TASL,PSPC1,LSM14A,CGAS,ALOX5AP,NPY5R,CASP4,KCNJ8,OTULIN,SYK,CD1D,HMGB1,NLRP1,FEM1A,MBL2,PYCARD,TRIM5,STAP1,CD226,EMILIN1,S100A8,CX3CL1,CAMK2N1,TNF,TRIM62,VAMP7,PHB1,LY96,TRIM6,KLRC2,PIK3AP1,PQBP1,TRIM3,IRAK4,CCL1,OSM,ZNRF1,SETD4,PTGER4,TLR8,IFI16,IKBKB,TRIM15,TLR1,TICAM1,IL15,ATAT1,IL23A,SRC,IL18,NECTIN2,NONO,PIK3CG,TLR4,HEXIM1,TOMM70,PHB2,IDO1,IFNG,CTSC,CD47,IL17F,NEK7,PDCD4,IL21,CLEC7A,CD14,MIR206,KLRD1,CNR1,BECN1,IFI35,PAK2,IL2,PLA2G5,TIRAP,NLRP6,TLR7,IRF7,DEFB114,FCGR1A,TRAF3IP3,OAS1,LTA,LACC1,PRKCE,VAMP8,DHX9,IL1B,PTPN22,CREBBP,NCR3,KLK3,TLR6,CCR7,FCN2,CLPB,GRPR,MIR144,KARS1,NFKBIA,EP300,KLK5,CCL24,TNFAIP3,HYAL2,MGST2,MYD88,SH2D1A,TLR9,IFNK,IFIH1,RTN4,MIR21,FABP4,CD81,LILRA2,MAVS,TAB1,CLEC6A,NMI,RIGI,SIN3A,TYROBP,IFNB1,CAV1,MEF2C,CASP12,OPTN,UCN,POLR3F,CD36,CD28,LDLR,HTR2A,HSPD1,BCL10,DDT,CD274,IL12A,MATR3,CCL3,RNF34,PELI1,FLOT1,IL6ST,IRF3,USP15,HSP90AA1,TLR3,UBE2K,POLR3B,IL12B,GPSM3,CCL5,NUPR1,MIR142,IL6,RSAD2,MIR126 |
| 1.950e-07 | -15.45 | VPS13A (vacuolar protein sorting 13 homolog A) | protein interactions | 23230 | 96 | 51 | 19454 | 5460 |
RAB9A,AKAP1,TOMM20,CDC42,POLR1D,SEC62,OTULINL,RND2,CNPY3,TOMM22,VPS4B,VAPB,SSR1,RMDN3,SEC61B,CYB5R3,VIRMA,RHOJ,ACTB,RAB2A,RAB11A,PDE7A,FIS1,UBE2H,RHOB,TMT1A,IMMP2L,FKBP8,ADD2,KRAS,EEF1A1,FAF2,DNAJC25,MTCH2,RPN1,TMEM31,RAB4A,HSD17B11,GJA1,RAC2,RAB35,LMAN1,DNAJC1,RHOH,ATG7,SLC25A46,EDEM1,RAB5C,DNAJC7,HAX1,RHOG |
| 1.957e-07 | -15.45 | DCPS (decapping enzyme, scavenger) | protein interactions | 28960 | 390 | 156 | 19454 | 5460 |
UBA3,GNAI2,DYRK1A,DEK,CDC20,CSTF3,MSN,RPS20,RPS12,MACROH2A1,ENO1,ACOX1,SF3B6,RPS3,RRP7A,AP2A1,ANAPC4,CDC73,LSM6,TUFM,KPNA6,RUNX1,RPL7A,AATF,HSPA5,BRIX1,WDR55,FBXW7,RBM22,PPP1R2,PDHB,HNRNPH2,PML,RARS1,UTP15,LSM2,RPRD1B,RPS14,DKC1,TMPO,THOC1,EIF2B5,CGAS,TOP1,MRPL50,RPL35A,RPS16,FZR1,PWP2,KRR1,RPL12,METAP1,SRP14,RPL10A,SMCHD1,TUBG1,SUV39H1,GAPDH,MDC1,RIGI,RPS13,KPNA2,THRAP3,NOC4L,NUP107,DHX9,RPL3,PIK3AP1,NAE1,SEMA7A,GNAI3,POLR2G,ACTR2,RBM34,CHAMP1,GINS4,DDX39A,H2AX,IMP3,SNRPB2,LRIF1,PPP5C,RPF1,RBBP4,TENT5C,PSMD6,SNRPD2,SNRPD1,S100A6,RCL1,THOC6,POLR1B,RIT1,LMNB1,FTSJ3,H2AZ2,SAMHD1,NOP16,GINS3,COIL,SRM,HNRNPA0,EMG1,SF3B1,ATP5MK,XRCC5,NCOA5,MFAP1,ATP5PO,SUPT4H1,H1-5,DHX15,SNRPD3,SNRPA1,ZNF740,NOP58,MEAF6,RPS10,HP1BP3,NXT1,EED,POLR2L,THOC2,FCGR1A,PDCD10,LAT2,NGDN,XPO1,BAZ1B,PRDX1,HMGA1,PRPF19,SSRP1,AP1M1,KRAS,RTCB,RUVBL2,TRIM21,TOP2B,HNRNPA2B1,SLC25A5,SART3,SNRPE,RPS11,SMNDC1,PDHA1,EZH2,CA14,GLE1,CSTF2T,EEF2,RPS7,MAK16,TUBA1A,ETFB,ACO1 |
| 1.968e-07 | -15.44 | HNRNPUL1 (heterogeneous nuclear ribonucleoprotein U like 1) | protein interactions | 11100 | 334 | 137 | 19454 | 5460 |
RBM22,FBXW7,DGCR8,HSPA5,MARS1,SIRT7,BAP1,RPA3,SQSTM1,GFM1,RNF113A,HNRNPH2,METTL14,GRM2,SAMM50,RPA2,KLF4,GIT2,HNRNPH3,HEXIM1,ATG16L1,KLF12,CFTR,PRMT2,AGO1,DYRK1A,VIRMA,SMURF1,EIF4A3,OPTN,CCNF,PTEN,RC3H2,IVNS1ABP,UBE2H,AR,PPP1CC,TUFM,NEDD8,RIGI,SMN1,FASTKD5,MEPCE,PSME1,RAB1A,DHX9,ERG28,NUPR1,ILF2,MRPL11,TP53,FBP1,METTL15,CD2BP2,MAP2K3,MAP1LC3B,EEF1A1,DCUN1D1,CAND1,RPS16,TMPO,RCHY1,ETV6,SYNCRIP,LDLR,TES,SNRNP70,H2AC4,GRSF1,COPS5,HDAC6,STAU1,HNRNPA0,UFL1,G3BP2,SNRPA,NGRN,DDX5,EP300,PIH1D1,MED31,ELK4,SNRNP40,MATR3,SNRPB2,APEX1,DES,USP5,CPSF1,TACO1,SF3B4,YWHAZ,FBXW11,BRCA1,ZMPSTE24,TMEM179B,CRMP1,OSGEP,CUL2,CFAP20,CUL3,MYC,BAG3,BTF3,MAPK1IP1L,G3BP1,HNRNPF,HNRNPDL,UBE2A,EWSR1,ELF1,DHX15,RAB11B,HSP90AB1,CACYBP,PEG10,FUBP3,PHB1,GATD3,EED,TSG101,AGR2,YWHAB,MRPS26,RB1CC1,DDX1,WWP2,MTRF1,PDIA3,IFI16,DDRGK1,ZNF207,YWHAG,HNRNPA1,XPO1,YWHAH,CPEB1 |
| 1.977e-07 | -15.44 | MTX2 (metaxin 2) | protein interactions | 10651 | 156 | 74 | 19454 | 5460 |
TOMM22,RPS14,TIMM29,FAXC,SAMM50,RPA2,SLC25A3,PDCL,EXD2,DDX39B,RPA3,AKAP1,MAVS,SQSTM1,TXNL1,SLC25A51,PHB2,YKT6,UFL1,TRA2B,BNIP3L,EXOC5,MAPRE1,HTRA2,VMP1,FIS1,CCDC90B,OPTN,VDAC2,LMBR1L,CHCHD6,EDNRA,ACTB,ESR2,PARL,CHCHD3,MTCH2,TPD52,APOO,SOX2,MGARP,CHMP4C,CARD19,NDUFA4,SFXN1,LRRN4CL,SLC2A8,CLPB,DNAJC30,USP30,KRAS,FKBP8,RNF26,IMMP2L,SRSF4,PDE2A,FAM174A,SLC25A46,MOV10,SLC2A1,DNAJC4,AREL1,COX4I1,PHB1,PTPN1,AIFM1,TRAK2,EED,RHOH,SLC25A12,PLGRKT,RMND1,COX14,DUOXA2 |
| 1.977e-07 | -15.44 | SUN1 (Sad1 and UNC84 domain containing 1) | protein interactions | 23353 | 156 | 74 | 19454 | 5460 |
ST7,OTULINL,RND2,TMEM106A,CDC42,SEC62,HSP90B1,GP9,SSR1,LMNA,TSPAN15,CYB5D2,TEX264,AKAP1,RAB9A,DERL1,CLEC12B,PXMP2,RAB11A,MYC,CSGALNACT2,RHOB,LMNB1,SDF2L1,DPEP1,ST8SIA5,GXYLT1,LMBR1L,SEC61B,RHOJ,ZNF507,SEC63,NRM,DNAJC25,APOO,CLEC2B,RAB4A,SFTPC,RPN1,PDE6D,NCR3,CRELD1,TMT1A,CYP2C9,TYW5,BSCL2,LRP3,DNAJC30,G3BP1,FKBP8,RAB5C,MARCHF5,SLC25A46,IFI16,MDFI,LAMP2,LAMP3,HSPB8,LRRTM1,ESYT1,RHOG,TSNAX,PEX3,PTPN1,RAB35,RAC2,GJA1,HSD17B11,RHOH,TNFSF18,DNAJC1,DNAJB9,LMAN1,TMPO |
| 1.996e-07 | -15.43 | OTULINL (OTU deubiquitinase with linear linkage specificity like) | protein interactions | 54491 | 402 | 160 | 19454 | 5460 |
DHRS1,SCFD1,VMP1,ZMPSTE24,SPCS3,SLC41A3,LRRC8C,SLC30A5,TMEM38B,VEZT,KDSR,ABHD12,CHP1,ATP6AP2,NDUFAF4,IP6K1,LRRC8A,REEP4,SPCS1,RETREG3,SLC30A7,GGT7,RMDN3,GPR89A,LMBR1L,FDFT1,VAPB,TMEM115,EMC9,BET1,GOSR2,TOR1AIP2,ITGAV,GOSR1,EMC1,NDUFS2,BET1L,JAGN1,ATP2C1,C2CD2L,CDK5RAP3,EMC6,DDRGK1,NDUFS8,PGS1,NUP35,OSBP,CYB5A,STX5,NDUFA12,TAPT1,CYB5B,PLD3,TMEM14B,STIM1,RPN1,FAF2,PLEKHA8,STBD1,MACO1,DCAKD,EMC10,SACM1L,SAR1B,RETREG1,EMC8,NUP42,SEMA4C,SCD5,SEC11A,TMEM87A,RINT1,TMT1A,NAPA,GGCX,SMPD2,ARFGAP3,HMOX2,GORASP2,C9orf72,VKORC1L1,SRC,SEC63,DHRS13,CAB39,ODR4,STX10,ATL1,LEMD3,USE1,GOLGA5,SSR1,TMX4,SLC12A2,TRAM1,SLC35E1,EHD3,ST7,RABL3,ARHGAP1,SEC22B,TMEM209,CERS2,YKT6,MTDH,SPCS2,DERL1,ITGA2,LRRC8D,GRAMD2B,TEX264,TMX2,RAB29,TMEM263,FADS2,NUS1,AREL1,OSBPL8,AGPAT1,POR,ESYT1,HM13,RAB23,KLHL22,EI24,TMEM199,SELENOS,DHRS7,EMC4,LMAN1,TMPO,STX6,SLC38A2,VTI1B,DNAJC1,ANKRD46,ARL6IP5,HSD17B11,SLC39A10,PTPN1,SSBP1,SRPRA,ITGA6,CAMLG,TMEM31,LBR,PREB,CCDC47,SLC6A8,FKBP8,RDH11,SRPRB,RAB27A,STX18,YIF1A,TMX3,EMC2,RUSF1,STX8,NSDHL |
| 2.004e-07 | -15.42 | PRPF19 (pre-mRNA processing factor 19) | protein interactions | 27339 | 405 | 161 | 19454 | 5460 |
PSMA2,KRAS,PRPS1,SSRP1,UBE2A,PFDN1,CCT8,DNTT,RPS24,CHMP4C,SMNDC1,PDHA1,EZH2,RPN1,GLE1,MOB3C,E2F4,KHDC4,RAF1,SOX2,SNRPA1,SNRPD3,BUD31,RPS10,DHX15,PPIA,SLMAP,EGLN3,PRCC,RBM5,PSMB4,SRSF1,EED,PPM1B,AGR2,HSPB1,MAGOH,AHSA1,WWP2,PFDN5,LAMP2,IFI16,PIK3R1,PRPF19,CTNNB1,DDRGK1,HNRNPA1,YWHAG,STAU1,KRT222,UFL1,UBE2D3,SRSF2,SNRPA,EP300,PSMA3,DDX5,HSPA8,SF3B1,HDAC5,EMC9,CTBP1,USP39,ACTL6A,NDE1,MTF1,SNRNP40,LGALS3,APEX1,BORCS7,PSMB6,DLST,CMTR1,SNRPD2,SF3B4,SNRPD1,BRCA1,GCC1,HSP90AA1,CUL3,MYC,SNRPB,RNF40,KPNA2,VRK1,TSSC4,CDC40,CTNNBL1,HUWE1,MEPCE,RNF20,TCOF1,BHLHE40,SNIP1,HSD17B10,EXOC3,DDX42,IFT57,NUPR1,ILF2,PPP4C,TBK1,ESS2,CD2BP2,TOP1,CAND1,FZR1,CWC15,CDC5L,ZBTB2,RBM42,SRP14,ECD,SNRNP70,KPNA1,MOV10,KARS1,COPS5,CSNK2A1,FBXW7,RBM22,NF2,DGCR8,AATF,MARS1,HSPA5,PRPF4,RPA3,DVL2,BAP1,RNF113A,CWF19L1,CZIB,RPA2,LMNA,HEXIM1,TFIP11,PPP1R8,WDR83,SF3A1,RBFOX2,CDK7,EGLN2,RAB14,VIRMA,ENO1,CTNNA1,GCFC2,EIF4A3,SF3B6,CCNF,STUB1,PTEN,RC3H2,ZNHIT3,UBE2H,NAPA,GSTK1,SEC13,PTPN11,AR |
| 2.007e-07 | -15.42 | MRPS12 (mitochondrial ribosomal protein S12) | protein interactions | 6183 | 239 | 104 | 19454 | 5460 |
CDK7,MRPL10,MRPS34,ACACA,GFM1,DLAT,TWNK,MRPL40,MRPL41,MRPL17,PDHB,NME4,MRPL20,POLDIP2,PYCR2,MRPS16,NRP1,RPS3,MRPL53,CCNF,ACAT1,MRPS28,MRPL47,NDUFA2,ATP5PB,BCS1L,PPIF,NDUFS3,MRPL49,ATP5PF,MRPL52,MRPS18B,ERG28,MRPS33,ZSCAN5A,MRPL22,MRPS18C,GRSF1,SNRNP70,SLC2A1,MGME1,MRPS9,METAP1,MRPL50,MRPL24,ZBTB2,MRPS23,NOTCH2,MRPL12,NDUFAF3,MRPS18A,NDUFA5,HADHA,ATP5IF1,UFL1,NDUFS2,MRPS7,HNRNPAB,PYCR1,MYC,NOA1,MRPS25,RIT1,CRMP1,DLST,TACO1,MRPL13,DKK3,TUBB,MRPL23,NDUFAF4,MAD2L2,RPL10,LRIF1,ETFB,RAF1,TOP3B,ERLIN2,TUBA1A,SOX2,PDHA1,NDUFS6,NUDT19,NDUFA12,PREPL,HINT2,ETFA,KGD4,KRAS,HNRNPDL,MRPS17,STOML2,MRPS35,DDX50,CLPX,CNOT2,DDRGK1,NDUFV2,MRPL9,MRPL18,MRPS26,HNRNPL,ERLIN1,NDUFS8 |
| 2.020e-07 | -15.41 | Vif-mediated degradation of APOBEC3G | REACTOME pathways | R-HSA-180585 | 55 | 36 | 10285 | 3229 |
PSMA2,PSMB6,PSMB2,PSMD1,PSMA6,PSMB3,PSMA4,PSMB10,PSMA5,PSMC5,PSMB11,PSMA3,PSMB5,PSMC1,PSMC4,PSMD12,PSMB7,PSMD3,APOBEC3G,PSMB1,RPS27A,UBA52,UBB,PSMD4,PSMC3,PSMD14,ELOC,PSMA1,SEM1,PSMB9,PSMD7,PSMD10,PSME2,PSMB4,PSME1,PSMD6 |
| 2.023e-07 | -15.41 | regulation of transmembrane transport | biological process | GO:0034762 | 485 | 195 | 18204 | 5365 |
FABP5,COX17,NFE2L2,EPO,FXYD6,PRRT1,OSBPL8,UBASH3B,SLC38A1,GSTO1,AMIGO1,PIK3R1,STOM,MIR153-1,OPRK1,MIR212,STIM1,IFNG,NLGN1,MIR133B,CACNB2,MIR34B,MIR873,MIR34A,MIR143,OAZ1,IL13,SCN1B,HPCA,MEF2A,MIR1-1,SESTD1,OAZ3,STAC3,KCNJ11,TMEM38B,PIK3CG,THY1,PDE4B,DLG4,LEP,APLNR,HOMER1,PHB2,PSEN2,NETO1,PTPN11,CRBN,PML,TMSB4X,JPH4,SPHK2,CXCL10,NHERF1,VAMP2,NPSR1,CCL2,PLP1,SRI,FGF13,ASIC2,DRD1,TERT,KCNJ8,CHRM3,CACNB4,NLGN2,AZIN2,KCNJ3,G6PD,CFTR,PLN,SCN2B,CAPN1,PPIF,CCR2,F2,SLC25A27,KCNJ10,SCN3B,CX3CL1,CACNB3,ISCU,MIR24-1,CD63,XCL1,ACTB,ADIPOQ,TNF,CLTRN,LACRT,YES1,CRHBP,VMP1,RGS2,TMBIM6,MIR495,RANGRF,HECW1,TESC,MIR208B,OAZ2,CAB39,EDNRA,CAV1,CLIC2,KCNAB1,GPR35,CAV3,FKBP1B,MIR210,MIR129-1,NDUFA4,CREBL2,NOS1AP,MIR208A,KCNIP3,TLR9,ARPP19,CACNG3,MIR21,PSEN1,ARL6IP5,SELENON,RNASEL,MIR185,DPP10,WWP2,CXCL9,KCNC1,PEA15,SLC43A2,MIR223,MIR107,MMP9,DAPK1,BAX,ATP1B3,AHCYL1,INPP5K,CA2,VDAC1,TRPC1,YWHAH,AKT2,KCNJ2,MIR186,OPRM1,FGF12,SNTA1,PRNP,OXSR1,CLIP3,ACTN4,SLMAP,PCSK9,ATP2B4,MIR200C,PPP3R2,KCNS1,FKBP1A,CTTNBP2NL,SUMO1,MIR448,CRHR1,GSK3A,KCNIP2,PRKCB,PRKCE,PID1,AZIN1,ATP1A2,SLC8A1,DLG1,ATP1B1,ABCB1,CHP1,MIR192,IGF1,KCNMB1,CXCL11,MIR9-1,GH1,SLC1A2,TCAF2,BAK1,AKT1,GSTM2,IL1B,PPP3CA,MIR30D,SELENOS,GRB10,ADRB2,DRD3 |
| 2.053e-07 | -15.40 | MRPS7 (mitochondrial ribosomal protein S7) | protein interactions | 51081 | 343 | 140 | 19454 | 5460 |
NOP16,CUL3,HNRNPAB,PMPCA,MYC,AUH,MTG2,MRPL16,MRPS25,MCAT,MTG1,CCDC90B,FAU,TACO1,RPS9,RPL7L1,RPL35,PARL,RPL19,RPL10,TOM1L1,FGF17,DUSP14,CTBP1,EXD2,NGRN,DDX39B,HSCB,UFL1,MRPS35,RPL6,MTRF1,DDRGK1,TRA2A,HNRNPA1,AK2,RHOG,MRPL18,CDK5RAP3,MRPS26,SRSF1,PHB1,RPL8,GATD3,RPL7,RMND1,ZNF263,TOP3B,TULP3,SOX2,PDHA1,MOB3C,PPAN,HNRNPA2B1,LSM14A,HSPD1,COX8A,SRSF7,MRPS11,HECTD3,HINT2,IMMP2L,SRSF4,MRPS17,NDUFB10,TUFM,RPL26,CALU,MAPRE1,DNAJC19,UBE2H,IGF2BP1,CCNF,PTEN,SRC,SMURF1,COQ8B,KLF12,RBMS2,FGFR1,GRM2,MRPS34,RPA2,KLF4,MTRES1,ZNF574,RPL26L1,HEXIM1,BAP1,PPM1G,GFM1,FBXW7,RPL4,HMGB1,CRYZ,UTP23,GRSF1,E4F1,CHCHD1,SNRNP70,TMEM70,TUBG1,USP15,DNAJC4,ALYREF,KRR1,ACTA2,RCHY1,SRP14,MRPS9,SSBP1,PRR3,TRMT10B,CGAS,FZR1,CAND1,SURF6,MRPS23,ZBTB2,RBM42,MRPL11,METTL15,H2AX,APOBEC3D,AURKAIP1,EEF1A1,GFM2,CLPB,RPL23A,MRPS18B,RPL3,DNAJC30,PSMA5,MRPS33,H3C1,RIGI,RPL17,FASTKD5,MRPS18C,MEPCE |
| 2.059e-07 | -15.40 | EIF2S2 (eukaryotic translation initiation factor 2 subunit beta) | protein interactions | 8894 | 225 | 99 | 19454 | 5460 |
METAP2,PSPC1,RPS12,CSNK2B,GSK3A,SUB1,USP14,EIF3G,MAPRE1,UBE2H,EXOSC1,BAP1,RPA3,RAB9A,MTDH,PRKCB,EXOSC4,FBXW7,TOMM20,UBA52,CFTR,EIF2B3,METTL14,FGFR1,RPA2,CD274,EIF2B5,PRNP,FZR1,RPS16,CAND1,CDC5L,RBM42,MBD5,TLE1,CSNK2A1,HDAC6,SNRNP70,SFXN1,IGF1R,TP53,RPL15,H2AX,AURKAIP1,DNAJC2,SRP72,RNF8,NUPR1,ILF2,SELENOF,CMTR1,RAN,CCDC90B,FAU,RPL37A,ZCCHC7,MAD2L2,RAB11A,CUL3,MYC,CDC123,NFYA,COPS7A,CYP1A1,NSA2,RIT1,CRMP1,XRCC5,TXNL1,STAU1,UFL1,G3BP2,BET1,TOMM22,ETF1,EMC9,MRTO4,PHB1,RPS10,NOP58,EIF2S1,TOR1B,VPS26A,HMGA1,DDRGK1,XPO1,AGR2,NCK1,DRG1,ETFA,KRAS,ZBTB16,G3BP1,RNF26,TULP3,TUBA1A,EZH2,MOB3C,RPS11 |
| 2.061e-07 | -15.39 | MRPL39 (mitochondrial ribosomal protein L39) | protein interactions | 54148 | 211 | 94 | 19454 | 5460 |
METTL14,PAK5,KLF4,MTRES1,UBE2M,RBMS2,MRPL10,MRPL41,MRPL40,MRPL17,MRPL20,NHP2,GID4,MTDH,GFM1,UBE2H,TUFM,NONO,VIRMA,MRPL53,MRPL49,MRPL51,MRPL33,GFM2,TP53,MRPL47,MRPL11,METTL15,AURKAIP1,RPL17,FASTKD5,MRPL22,MRPL52,TMEM70,SNRNP70,CHCHD1,GRSF1,MRPL50,CAND1,MRPL24,MALSU1,MRPS9,SSBP1,PRR3,MRPS18A,MED23,RPL27A,DUSP14,MRPL12,MRPL57,HSCB,TRA2B,RANBP10,EXD2,NGRN,HSPA8,MRPL34,BRCA1,MCAT,CUL3,PMPCA,MTG2,AUH,MYC,MRPL16,LAMTOR3,MRPL23,RPL19,RPL10,MTG1,DLST,TACO1,MRPL13,SOX2,KRAS,H1-6,UTP25,HSPD1,HINT2,EWSR1,MRPL18,SKIC8,RHOG,ARMC8,MRPS26,RPL6,MTRF1,TRA2A,MRPL9,HNRNPA1,HMG20A,SRSF10,FBXO32,GATD3 |
| 2.118e-07 | -15.37 | WDR41 (WD repeat domain 41) | protein interactions | 55255 | 127 | 63 | 19454 | 5460 |
RPA3,EXD2,RAB5A,AKAP1,RAB9A,MAVS,DERL1,PXMP2,TOMM20,TSPAN5,STX7,TOMM22,OTULINL,RND2,SEC62,CDC42,ST7,RPA2,SSR1,FGFR1,RMDN3,SEC61B,MGST3,RHOJ,SEC63,RAB2A,C9orf72,RAB11A,ATG101,LAMTOR1,FIS1,CYP2C9,TMT1A,DNAJB4,PICK1,IGF1R,KRAS,RAB3B,FKBP8,MTCH2,DNAJC25,STIM1,RPN1,RAB4A,PTRH2,FURIN,PTPN1,RAB35,ARL10,HSD17B11,DNAJC1,ARF6,RHOH,LMAN1,COX14,LAMP2,RAB5C,MARCHF5,SLC25A46,LAMP3,RHOG,RB1CC1,DNAJC7 |
| 2.136e-07 | -15.36 | SEPTIN7 (septin 7) | protein interactions | 989 | 200 | 90 | 19454 | 5460 |
MTCH2,YTHDF2,UBR7,MAP1LC3B,AURKAIP1,IK,SURF4,NUPR1,RNF8,SH3GLB1,DYNC1I1,RIGI,LAMP3,HDAC6,SMCHD1,SRP14,HRAS,ARF6,CDC5L,CDK9,ARHGAP1,CFTR,CDC42,METTL14,ZNF326,RPA2,RPA3,SEPTIN6,BAP1,SQSTM1,CDC42EP4,HSPA5,SUB1,RAB2A,SMARCA5,GORASP2,BICD2,CHORDC1,UBE2H,CCNF,UBE2I,COPE,VIRMA,HEXA,E2F4,TPBG,SOX2,NCSTN,MOB3C,TOP2B,SCYL2,SRSF7,CDK5,KRAS,FLOT1,RAB5C,LAMP2,TRA2A,XPO1,DRG1,NAB2,PRCC,RAB35,ATP6V1A,GJA1,SNRPA1,BUD31,DIRAS3,MRPL12,PPT1,GRIK1,DNAJC3,CDC42EP2,HSPA8,SSR3,TRA2B,SAP18,STX7,HNRNPC,MYC,HMGCS1,BRCA1,RHOB,RIT1,BAX,VDAC2,CDC42EP3,LMBR1L,TENT5C,ESR2 |
| 2.160e-07 | -15.35 | SKIC8 (SKI8 subunit of superkiller complex) | protein interactions | 80349 | 228 | 100 | 19454 | 5460 |
NDUFA2,CCT5,CENPM,MRPL36,CDK8,DNAJC2,ACVR1,MRPL33,TAF2,MSRB3,H3C1,PSMA5,PDRG1,MRPL22,KARS1,RBM17,COPS5,SLC35A1,RPL24,MRPS9,FZR1,TOP1,PRNP,CGAS,MRPS23,SF3A1,CCND1,SEC22B,MRPL10,CFTR,DCTN4,USE1,RARS1,RPA3,BAP1,PGK1,TCEA1,UBE2K,CIAO1,PTPN11,PPP1CC,CDC73,UBE2H,CCNF,SF3B6,MRPS21,SMURF1,DUSP10,UBA3,VIRMA,DYRK1A,ERRFI1,HEXA,SUPT5H,EZH2,SF3B5,LTO1,RINT1,CCT8,MRPS11,SRSF7,PFDN1,SSRP1,COPS4,IFI16,PFDN5,WWP2,XPO1,CDC23,PHB1,PPP2CB,TCP1,CHMP2A,CCT7,MRPS18A,PIH1D1,SNRPA,SF3B1,MRPL57,PYGB,G3BP2,CUL3,GRB10,RNF40,PSMD1,SNRPB,TTC33,CCT2,PFDN2,PFDN4,RIT1,PFDN6,H1-1,PELO,RAN,SNRPD2,MCPH1,MRPL13,ESR2,SNRPB2 |
| 2.166e-07 | -15.35 | regulation of viral process | biological process | GO:0050792 | 168 | 81 | 18204 | 5365 |
MIR130A,APOBEC3F,IFI16,PPIH,APOBEC3H,PLSCR1,CD4,BANF1,IFNA2,STOM,TRIM26,CSNK2B,SLPI,TRIM22,IFIH1,APOBEC3A,TRIM10,HACD3,SNX3,EIF2AK2,MIR141,CD28,KPNA6,OAS1,PABPC1,TSG101,KPNA2,TRIM11,IFNB1,FURIN,CNOT7,TRIM15,APOBEC3B,TMEM39A,BST2,STAT1,MAVS,ISG15,CXCR4,HEXIM1,TRIM5,ISG20,TRIM27,TRIM21,NECTIN2,PPARA,PROX1,APOBEC3C,APOBEC3D,MORC2,MBL2,TOP2B,CH25H,HS3ST5,HMGB1,TRIM34,PPID,INPP5K,MX1,DHX9,RSAD2,STAU1,TRIM32,TRIM8,APOBEC3G,TRIM6,PPIA,VPS4A,TRIM62,PDE12,UBP1,LAMP3,DDX5,TNF,CXCL8,CD209,VAPB,CCL5,SRPK2,TRIM68,RNASEL |
| 2.179e-07 | -15.34 | RBMS2 (RNA binding motif single stranded interacting protein 2) | protein interactions | 5939 | 245 | 106 | 19454 | 5460 |
MIR205,MIR34C,MRPL40,MRPL41,MRPL17,MRPL20,MIR29A,RBFOX2,MIR1-2,AGO1,MRPL10,ZNF326,MRPS34,MIR7-1,RPL26L1,SMAP2,ENO1,PHAX,MRPS28,MRPS21,EIF4H,ZNHIT3,CASC3,CDKN2AIP,PAIP2,ELAVL2,IGF2BP1,GLUL,MRPL52,EHD4,ZC3H11A,MRPS18B,MRPS33,MIR16-2,MIRLET7C,MRPL22,MRPS18C,YTHDF2,MRPL11,MRPL47,STRBP,APOBEC3D,MRPL51,MRPL49,MRPL33,KRR1,SYNCRIP,MRPS9,PRR3,MRPL50,PRNP,MRPL24,CDC5L,MALSU1,DKC1,CMSS1,MOV10,APOBEC3F,NGRN,AKAP1,MRPL57,STAU1,TRA2B,MRPS7,PABPC5,DET1,LARP4B,MRPS18A,NUFIP2,MRPL13,MRPL23,PRRC2A,HNRNPC,CUL3,MYC,APOBEC3B,MRPL16,NOA1,MRPS25,DCAF4,H1-1,GTPBP2,MCAT,MIR9-2,PABPC1,MRPS11,MIR155,NUP42,G3BP1,H1-6,MRPS17,PAIP2B,MIR222,SOX2,SART3,FUBP3,MIR7-2,HNRNPL,PAIP1,NUP35,SRSF10,MRPS35,XPO1,MRPL9,MRPL18,MRPS26 |
| 2.202e-07 | -15.33 | MSH2 (mutS homolog 2) | protein interactions | 4436 | 288 | 121 | 19454 | 5460 |
AKT1,CAP2,HSPA14,SLC25A1,SMARCA5,ST13,EPHA2,ZBTB38,DTL,ATP1A1,UBE2H,CALML5,RPGRIP1L,VIRMA,TPT1,CDC42,SETD3,JUP,RPA2,LMNA,FBP2,METTL14,STX17,RPLP0,UBE2M,WTAP,RPA3,NBN,SIRT7,DGCR8,HSPA5,HDAC6,SLC2A1,TDRD7,HRAS,RB1,SEC23A,TES,TOP1,PTP4A3,IAH1,CDK9,CDC5L,FBP1,TP53,GBE1,EEF1A1,H2AX,SMAD1,GGCT,PPP3R2,CDK8,IK,NUPR1,RAD1,GALNT12,H3C1,SMN1,MSH6,ALDH1L1,CREBBP,MYC,CUL3,CUL2,PDE4B,MCM8,BRCA1,PFDN4,RPS5,TRMT6,LMBR1L,MATR3,TRIM29,TUBB,ESR2,MAD2L2,NEK7,CDKN1A,PIH1D1,ANXA7,RFC4,XRCC5,APPBP2,EP300,STAU1,EEF1G,COIL,RPP14,PPIB,XPO1,DDX23,FKBP4,CBL,HNRNPD,MGMT,HSPB1,FABP5,FBXO32,SUMO2,SRSF10,EGLN3,DHX15,CEP19,RAF1,MAX,FEN1,ZNF263,E2F4,SUPT5H,ARFGEF1,FAF2,VPS33A,MOB3C,RNF126,TOP2B,PCNA,RPS24,SRSF7,AP1M1,SSRP1,RAD21 |
| 2.204e-07 | -15.33 | BMP4 (bone morphogenetic protein 4) | protein interactions | 652 | 135 | 66 | 19454 | 5460 |
RPS23,RPL18,RGMB,RPS11,BMPR2,GPX7,CBLN4,RPS7,TOP3B,RPL28,RPS13,ADIPOQ,TNFSF8,DHX9,RPL3,RPL23A,EWSR1,PABPC1,RPL31,RPL23,MAP4,HNRNPA1,RPL6,CFC1,PROS1,BMPR1B,CALR,RPL7,TOP1,TWSG1,HTRA1,RPL35A,SOSTDC1,RPL8,RPL12,SYNCRIP,RPL9,RPLP0,P3H1,SUFU,RPL27A,CLU,HSPA5,RPL4,STAU1,GREM2,FXR2,NOG,RPL27,BMPR1A,DCAF16,H1-10,SDF2L1,CHRDL1,RPL26,HNF1B,RPL10,SRPK2,RPL19,RPL22,ZNF622,RPS9,RPS20,HS3ST1,EIF4A3,RPS3 |
| 2.204e-07 | -15.33 | MRPS15 (mitochondrial ribosomal protein S15) | protein interactions | 64960 | 135 | 66 | 19454 | 5460 |
KLF12,RBMS2,METTL14,MRPS34,MTRES1,KLF4,ZNF574,HEXIM1,BAP1,SNRPA,MRPS7,CUL3,MYC,PRKACB,NOA1,MRPS25,MRPS16,H1-1,UBE2H,MCAT,EXOC8,CDC73,RPS9,MRPS28,MRPS21,SRC,ESR2,RPL10,RPL19,MRPL11,STRBP,AURKAIP1,PDHA1,HSPD1,MRPS11,SRSF7,COX8A,MRPS18B,MRPS33,VPS16,MRPS17,MEPCE,MRPS18C,MRPS35,RPL6,GRSF1,TRA2A,TMA16,COPS5,HNRNPA1,SNRNP70,LHX2,MRPS26,POU5F1,ALYREF,SRSF1,RCHY1,MRPS9,ACSL4,PRR3,TRMT10B,MPP1,CGAS,FZR1,CAND1,MRPS23 |
| 2.206e-07 | -15.33 | H1-8 (H1.8 linker histone) | protein interactions | 132243 | 42 | 28 | 19454 | 5460 |
RPL27,RPL3,STAU1,H1-6,BRIX1,RPL17,RPS27A,RPS14,RPL15,RPL29,LLPH,GLE1,RPL26L1,RPL32,RPS3,ZNF22,RPL8,HP1BP3,RPL37A,RPF1,RPL13A,RPL22,SURF6,RPL19,RPL6,RPL7A,FTSJ3,H1-1 |
| 2.229e-07 | -15.32 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | biological process | GO:0000377 | 251 | 112 | 18204 | 5365 |
RBM22,SNRNP40,TRA2A,ESS2,PPWD1,ZCRB1,SYNCRIP,PQBP1,DDX46,CTNNBL1,BUD31,SNRPA,DHX16,SNRPG,TFIP11,SNRNP70,RNF113A,CDC40,METTL14,LSM6,KHDC4,UBL5,SRSF10,SRSF4,CELF6,GEMIN7,SRSF1,PPIL3,SNIP1,HSPA8,LUC7L3,SF3B4,TSSC4,RBMX2,RBM41,HNRNPA2B1,SRSF12,NOVA1,SNRPB,SF3B6,HNRNPK,USP39,SMN1,DDX23,DDX42,HNRNPA1,SNRPB2,DDX1,SLU7,NCBP2,DDX5,LSM5,SCNM1,DDX39B,MAGOHB,DHX38,SNRPD1,PRPF31,SART3,CWF19L1,CWC15,TXNL4A,CASC3,PPIH,MFAP1,LSM8,SF3B5,DDX39A,LSM3,FRA10AC1,GCFC2,RBM42,COIL,CDC5L,HNRNPF,RBM5,SNRPD2,DHX15,PRPF19,PRPF18,TRA2B,CD2BP2,PABPC1,SNRPA1,RSRC1,HNRNPC,IK,SMU1,SNRPE,DBR1,WDR83,DHX9,LSM4,SNRNP27,HNRNPH3,PRMT5,SF3A1,SRSF7,PRPF4,SRPK2,GEMIN8,SNRPD3,MAGOH,SRSF2,WDR77,SRSF8,RBM17,SF3B1,ZMAT2,SNRPN,EIF4A3,LSM2 |
| 2.229e-07 | -15.32 | mRNA splicing, via spliceosome | biological process | GO:0000398 | 251 | 112 | 18204 | 5365 |
LSM2,SNRPN,ZMAT2,EIF4A3,WDR77,SRSF2,SF3B1,RBM17,SRSF8,SRPK2,GEMIN8,SNRPD3,MAGOH,PRPF4,SRSF7,SF3A1,LSM4,SNRNP27,HNRNPH3,PRMT5,WDR83,DHX9,DBR1,PABPC1,CD2BP2,SNRPA1,RSRC1,SNRPE,IK,HNRNPC,SMU1,TRA2B,PRPF18,SNRPD2,RBM5,COIL,RBM42,HNRNPF,CDC5L,PRPF19,DHX15,DDX39A,LSM3,FRA10AC1,GCFC2,LSM8,SF3B5,PPIH,CWC15,CASC3,TXNL4A,MFAP1,SART3,PRPF31,CWF19L1,SNRPD1,DDX5,NCBP2,LSM5,SLU7,DDX39B,MAGOHB,DHX38,SCNM1,DDX42,DDX1,SNRPB2,HNRNPA1,DDX23,HNRNPA2B1,SRSF12,RBM41,NOVA1,SNRPB,HNRNPK,USP39,SMN1,SF3B6,RBMX2,TSSC4,SF3B4,LUC7L3,PPIL3,HSPA8,SNIP1,SRSF1,GEMIN7,SRSF10,SRSF4,CELF6,UBL5,LSM6,KHDC4,RNF113A,METTL14,CDC40,SNRPG,DHX16,SNRPA,TFIP11,SNRNP70,DDX46,CTNNBL1,PQBP1,SYNCRIP,BUD31,ESS2,TRA2A,PPWD1,SNRNP40,RBM22,ZCRB1 |
| 2.238e-07 | -15.31 | AHCYL1 (adenosylhomocysteinase like 1) | protein interactions | 10768 | 367 | 148 | 19454 | 5460 |
PPP1R12A,MAP1B,CAMKV,RASL10B,VRK1,FGF12,THRAP3,PTGES3,SEPHS1,FAM13B,CCT5,CD2BP2,UBE2V1,GINS4,UBE2B,RAC2,TES,FZR1,MIF,AKAP17A,MYL12A,STX6,CAV1,MOV10,COPS5,TPM3,SNRNP70,STYK1,SOD1,RPA3,PPM1G,SNCG,RHOU,BAP1,RBM23,PML,CLK1,SMC4,HSPA5,CPSF4,UBA52,SPR,CDC42,CFTR,VPS4B,RPA2,PTP4A2,FGFR1,HEXIM1,HECTD1,STAT6,RPS3,STUB1,TUBA1B,SNX12,HEXIM2,SYT2,SGTA,PTEN,MACROH2A1,TMOD3,TXN,ADRM1,RHOJ,SNX3,UBE2L3,SRPK2,SMARCA5,PTPN11,DNAJC5,AR,PIP4K2C,ATP1A1,UBE2H,ZYX,CDKN2C,RBBP7,UFM1,EPHA4,PSMA1,KRAS,GNL1,RUVBL1,PSMD12,UTP25,AHCYL1,PAK6,ANP32B,ANP32A,ZNF263,CSNK1E,PTS,PPIL3,SOX2,JUN,ACTN4,FBXL7,TNPO2,TULP3,NFKBIL1,STMN2,TUBB4B,ZRANB2,RND3,HGS,CLK4,SIN3A,RAB35,SRSF1,TYMS,COPS2,TTC9C,SUMO2,MAPK4,VPS26A,XPO1,FAM241A,SPON1,NT5C2,UBE2D1,RHOG,SNRPA,HSPA8,YAF2,TTC1,UCHL3,EEF1G,SKP1,SEC62,TOM1L2,SOST,MYL6,SRXN1,DOK4,RPL37A,TAGLN2,PSMD4,PSMD6,TNPO3,BTG3,MYC,HNRNPC,PLEKHJ1,PSMD14,FBXW11,HSP90AA1,NTRK3,SERPINH1 |
| 2.240e-07 | -15.31 | Activation of NF-kappaB in B cells | REACTOME pathways | R-HSA-1169091 | 68 | 42 | 10285 | 3229 |
PSMA3,PSMB5,PSMC4,PSMC1,PSMD12,BCL10,PSMB7,PSMD3,NFKBIB,PSMB1,PRKCB,PSMD1,PSMB2,PSMA2,PSMB6,FBXW11,PSMA6,PSMB3,PSMA4,NFKB1,PSMB10,PSMA5,PSMB11,PSMC5,SEM1,PSMB9,NFKBIA,PSMD7,PSME2,PSMD10,IKBKB,PSME1,PSMB4,SKP1,PSMD6,RPS27A,UBA52,PSMD4,UBB,PSMC3,PSMD14,PSMA1 |
| 2.262e-07 | -15.30 | ELOC (elongin C) | protein interactions | 6921 | 231 | 101 | 19454 | 5460 |
CBFB,S100A8,MRAS,EGLN3,DHX15,IFI16,WWP2,ASB1,DDRGK1,FEM1B,CENPW,CISH,CSTA,ASB7,POU5F1,DRG1,CPTP,RBM3,CCT8,KRAS,XPNPEP1,COPS4,B3GNT2,RAF1,FAF2,DNAJC25,PLS3,EZH2,GHR,MOB3C,DIO2,TCEAL1,CBX5,APEX1,ESR2,CUL2,CUL3,OSGEP,ILK,RAB40AL,APPBP2,DDX5,EIF1B,ADRB2,MCMBP,ASB3,ASB8,TANK,PRDX3,RNF7,FEM1A,ZER1,PIH1D1,CTDSPL2,SOCS4,DCUN1D1,FZR1,ASB11,PRNP,LRRC14,MOV10,COPS5,SAT2,EPOP,PSMD7,ID1,MAP1B,SPSB1,ABCE1,SERTAD1,NEDD8,DNAJC30,HNRNPK,SOCS2,RNF20,CAPZA1,SOCS3,DDX39A,PCMTD2,SPSB3,CCNF,MAT2A,FBXO7,DNAJC8,NEURL2,NAPA,UBE2H,BAP1,RPA3,SQSTM1,RNF113A,FBXW7,GABARAP,ATG16L1,SPR,ARHGAP1,WSB1,CFTR,METTL14,UBE2M,HEXIM1 |
| 2.271e-07 | -15.30 | BMPR1A (bone morphogenetic protein receptor type 1A) | protein interactions | 657 | 203 | 91 | 19454 | 5460 |
SF3B4,AP2M1,SEC61B,RAN,ZNF189,APLNR,TAB1,MANSC1,TUBB,MYC,HSP90AA1,DESI2,PSMD14,LMNB1,RHOB,HSPA8,OR1M1,ARRDC3,BMPR1A,SLC31A1,CD59,GINM1,FKBP1A,MAP2K1,PEG10,HSP90AB1,CX3CL1,CTNNB1,CNOT2,SEC61A2,WWP2,SLC20A1,PDCD1,RUVBL2,CD83,TRMO,GFPT1,TMEM59,IFNGR1,TMEM204,AQP3,CIB2,SFRP4,SMURF1,GNAI2,RHOJ,ATP5F1A,IFNAR1,TUFM,SLC25A1,FKBP1B,AP2A1,TLR2,RHOU,SNX11,CLDND1,TICAM2,HSPA5,LITAF,IGFBP3,CDC42,AVPR1B,FBP2,HRAS,RPRM,CDK9,CAV1,MARCHF4,CAND1,ZMYND11,MICB,BMPR1B,USP15,RNF133,TSPAN17,GALNT12,RUSF1,TGFBR2,EEF1A1,SMAD1,FBP1,TBK1,CTXN1,RGMB,IL20RB,FURIN,CTLA4,CDK8,BMPR2,ACVR1,ACADSB |
| 2.281e-07 | -15.29 | CDK1 (cyclin dependent kinase 1) | protein interactions | 983 | 560 | 212 | 19454 | 5460 |
PPM1B,BCL2L1,PPP3CA,CDKN1B,LYZ,HMGA1,PRDX1,CCAR2,RGCC,STK3,LRWD1,EGLN3,MRTO4,PHB1,DNM2,VPS33A,EZH2,E2F4,CKS1B,RAF1,FEN1,ERLIN2,PPP2R1A,G3BP1,ZBTB16,FANCG,SAR1B,UBE2A,GADD45A,SCYL2,MEF2C,SLC25A5,UBE3A,PCNA,ZC3H7A,BRCA1,LMNB1,RIT1,HTRA2,NTRK3,HSP90AA1,SP1,CUL3,NFYA,MCM4,SAMHD1,TUBB,PRDX2,ERH,PELO,KCTD12,PSRC1,MFAP1,PGRMC1,H1-5,KCND3,NDE1,DUSP22,CDKN1A,TIMM29,NSFL1C,CCND3,COIL,FGR,TLE1,GTF2E1,HDAC6,TOP1,ARF6,MRPS23,PTPN1,CTDSPL2,H2AZ1,RB1,DCK,TES,CCT5,MAP1LC3B,POLL,CNOT7,HUWE1,DUSP21,PPP1R12A,HSD17B10,IGF1R,PIP4K2C,CIAO1,USP14,PPP1CC,GMNN,RACGAP1,AR,NONO,RUNX1,YES1,NDN,COPE,TXN,CCNF,OPTN,UBE2I,GRM2,JUP,LMNA,CDK1,MTRES1,CCND1,NFYB,CCNA2,CDK7,FBXW7,HMGB1,NF2,DCTN6,SIRT7,RPA3,DVL2,SQSTM1,PRKCB,HSPB1,ARMC8,MGMT,IFI16,CTNNB1,DDRGK1,XPO1,TCP1,CDK17,CCT7,RAB4A,STMN2,MOB3C,ZRANB2,H1-3,SOX2,VDAC1,KRAS,PAK6,GADD45B,CHTOP,LAMTOR1,H1-1,CDKN3,SFN,MYC,BAG3,CUTA,PSMD1,MATR3,USP16,GADD45G,DLST,IRF2,ACAA2,CKS2,PAFAH1B1,STAU1,BOLA2B,UFL1,DDX39B,EP300,HDAC5,CCNI,SNRNP70,H2AC4,CXCR1,MAP4,CSNK2A1,NKAP,FZR1,TMPO,ALYREF,SSBP1,CDK6,ADD1,MCL1,TMEM165,NHERF1,NUPR1,RNF8,BIRC5,TP53,CDK4,KBTBD4,MVD,IKZF5,TGFBR2,AKAP12,PSMA5,MEPCE,IDH1,SPOP,UBE2H,PTTG1,DTL,ANAPC4,CCNB1,TIA1,SRC,CDC20,PSMA6,CREB1,RPS3,MACROH2A1,CSNK2B,IDH2,BTG2,FGFR1,RPA2,HEXIM1,PML,BAP1 |
| 2.309e-07 | -15.28 | regulation of multicellular organismal development | biological process | GO:2000026 | 1484 | 524 | 18204 | 5365 |
PRMT5,DRD3,AMELX,SMAD4,INO80E,PPP3CA,WNT7A,AKT1,BMP1,IL1B,TNFAIP3,CTNNB1,MAP1B,VDR,CTSK,CCL24,MT3,OXTR,TOX,RETN,IGF1,NFKBIA,DR1,EP300,PDCD10,SPRED1,SKIC8,ASPA,CTDSP1,CCND1,MIR221,MIR130A,IL2,TGFBR2,MIRLET7B,CARTPT,SLC8A1,SOD1,RND2,MIR492,MIR377,XBP1,KIT,FLRT3,RLN2,L1CAM,GSK3A,RGMA,BAD,CD34,PTEN,MIR125A,FGF1,STAT1,NRP1,HAX1,MIR10A,SPRY1,PPARA,GPR137,EMC10,SMARCE1,VEGFC,KLHL25,GPR37L1,OTX2,JUNB,PPP1R12A,PRL,ACTL6A,PNP,PLXNC1,LDLR,AKT3,FOXP3,MIR1224,ERRFI1,MIR885,FUT1,SLITRK5,HAPLN2,IL6,ID4,BTG1,MMP9,BGLAP,CD86,ASPM,FOXP1,GPM6B,LRRTM1,NKX3-2,TMEM100,MIR223,MIR185,MMP14,IL12B,MIR375,MSX2,ANAPC2,SYT4,SFN,IFNA2,MIR30B,MIR21,INHA,CDC73,MMP20,TLR9,PLCB1,TNFRSF1B,SMARCD3,EMP2,RTN4,MIR548C,ADM2,SMURF1,ELAPOR2,ZBTB16,GPRASP3,JAK1,RGCC,MIR210,CD80,PAX6,TSPAN18,MIR204,WNT10B,FBXW7,NME2,NOG,FCGR2B,TESC,SGF29,HDAC6,STK11,MIR205,PITHD1,FGF16,SYK,PROM1,MACROH2A2,SAV1,ACVR1B,KLF10,CD40,RAB14,MINAR1,WNT2,TRIM32,SLITRK2,GLUL,GPR171,CD2,VSIR,MIR24-1,MIR101-1,SMAD3,CERS2,ATRAID,PARP2,PTHLH,LRTM2,CCL19,EEIG1,RNF10,LRRN1,TRIB1,MIR378A,XRCC5,NINJ1,CTLA4,SGMS2,TLR2,G6PD,AGGF1,FXR2,TRAF6,GADD45A,NLGN2,SLC12A2,MIR222,CYP1B1,IL15RA,MIR16-1,TERT,FGF13,BMPR1B,IL2RA,DUSP6,FOS,HCLS1,CHI3L1,DISC1,JMJD8,PML,FGL2,UTP25,KRIT1,ATF4,PIK3CG,MIR939,THY1,RNF41,FASLG,LEP,TNFSF12,IL18,SRGN,MTMR2,DAG1,MIR34C,TMEM176B,HOXB8,ROCK1,CAMP,MIR143,MIR15A,PAFAH1B1,MIR34B,IL17F,MIR873,TIAM1,TCIM,NLGN1,IFNG,FIG4,PGK1,FLRT2,NIBAN2,NTRK2,STIM1,FZD4,CTNNBIP1,NR2E1,PIK3R1,IRF1,MIR30E,AMIGO1,IL23A,BMPR2,SEMA7A,VEGFA,TFE3,MIR29A,NF2,UBASH3B,HSPB6,PRMT6,FBXO7,NFE2L2,MIR137,IL15,BMPR1A,MIR181C,PRELID1,FGF23,SLITRK1,MECP2,SMARCB1,SEMA5A,KLK3,ISG15,TPPP,MTDH,BHLHE40,PROX1,GREM1,ADRB2,WASF3,DKK1,RFLNA,C1QC,SPP1,MIR25,FAM20C,FGF10,ADD1,ADAMTS1,SPRED2,IL2RG,NOTCH2,KRAS,TGFB2,IL1A,SNAI2,DICER1,CBLN1,IFRD1,MAFG,DLG1,GHRL,RGN,MIR20A,TADA3,PROK1,CTNNA1,FZD3,TNR,RHEB,SOX9,NDFIP1,LTA,TOB2,MAP2K1,CCR1,PRKCB,PPP1CC,HGS,TMEM176A,MIR200C,ATP2B4,IL5,SMAD1,IRF7,MIR29C,KDM1A,MACROH2A1,ING5,BTN2A2,IL6ST,HEY2,SYNDIG1,TGIF2,OPRM1,CFL1,FRZB,YWHAH,SASH3,CD83,CCL3,MIR132,CDK1,OSR2,LILRB1,MYC,CREB1,MIR126,SFRP1,SLC20A2,NUPR1,AGO1,HSPB1,LRRTM3,MIR142,EFNA3,MIR106B,SOS2,EPHA4,TLR3,DLX1,CD46,AQP3,CBLN2,CD4,PTN,EGR2,PSEN1,MIR146A,LILRB4,MIR208A,RUNX1,ZMPSTE24,SOCS5,TCTA,IL4,NPTN,BRCA1,MIR31,VGLL4,CMA1,CBFB,CD28,PTPRZ1,SEPTIN7,MEF2C,MIR150,EFNA5,CAV3,RUVBL2,TYROBP,CAV1,IFNB1,TRIM11,RC3H2,MEAF6,EMILIN1,TBC1D24,ITGB8,CXCR4,S100A10,TRIM46,GABPA,LRRC24,AGER,MIR361,ZNF304,MIR23A,BATF,RHOB,DUSP10,IL1RAP,TAPT1,MIR495,HMGB1,DDAH1,MME,CXCL12,BCL6,INO80C,EPHA2,CDK5,RGS2,TESPA1,NKX6-2,MSX1,CX3CR1,MIR145,CCM2,RUVBL1,PRKX,LRRTM2,CCR3,ACTB,TNF,ADIPOQ,MIR505,CX3CL1,MIR1298,FERD3L,ROCK2,MIR640,IL10,RBPJ,F2,FOXC2,CCR2,IRF4,RHOH,GJA1,PRKCA,NEFL,CFTR,MIR17,MIR214,NLRP3,ACVR1,LDB1,ASIC2,RAG1,LRRC4B,ZNF365,MIR424,ANKH,ADNP,RB1,CXCL10,KLF4,ZBED3,CCL11,TOMM70,PTPN11,MIR590,CDK6,TFPT,APLNR,TLR4,MGP,FGFR1,VASH1,NKAP,MIR99B,PRDX2,CRABP2,HELT,TNFAIP6,MITF,SYNJ2BP,MIR1-1,MIR34A,IL13,BRINP1,ACTL6B,CXCL8,FKBPL,TP53,CTSC,CXCL13,RACGAP1,SP1,UFL1,MIR503,CLSTN3,PPARG,MIR212,SFRP4,MIR30A,GAB1,BTG2,TSPO,CDKN1B,MIR193A,F11R,GPNMB,JUP,FAXDC2,RHOJ,PI16,YTHDF2,CCSAP,B2M,MIRLET7G,LHX2,IL7,CHRNA7,EZH2,DROSHA,GTF2I,LGALS3,TPBG,CYP27B1,MYRF,IL34,IKBKB |
| 2.343e-07 | -15.27 | HCFC1 (host cell factor C1) | protein interactions | 3054 | 271 | 115 | 19454 | 5460 |
FBXW11,MYO6,BRCA1,RIT1,SETD7,SP1,HSP90AA1,CUL3,MYC,SNRPB,KANSL3,PRPF31,IRF1,THAP7,SIAH1,RBBP4,FBXO22,TNPO3,RAN,IRF2,EMC9,PIH1D1,THAP2,THAP6,PPP1CB,SNRPA,DR1,HDAC5,HSPA8,DPY30,WWP2,TAF7,HMGA1,ACTL6B,SUMO2,HSP90AB1,EGLN3,PPIA,SIN3A,EED,WDR82,EZH2,MOB3C,SMARCB1,TXNRD1,E2F4,TOP3B,RAF1,MAX,SAP30,EEF2,NFE2L1,NUDCD3,JUN,ASF1A,FOXN2,RUVBL1,KRAS,RBBP7,RERE,SSRP1,HNRNPDL,RUVBL2,INO80C,UBE2H,ZBTB38,SMAD2,CREB3,CARS1,AR,TUFM,PPP1CC,GABPA,BUB3,ZBTB17,VIRMA,DDAH2,PELP1,CCNF,SGTA,SENP5,CSNK2B,RPA2,LMNA,HEXIM1,SNRPN,ATG16L1,CREBZF,HSPA5,CXXC1,HCFC2,PML,SIRT7,BAP1,RPA3,H2AC4,PSMD7,CLP1,TAF9,GAPDH,CSNK2A1,TOP1,MBD5,POLE3,H2AZ1,AIFM1,GABPB1,TP53,KBTBD4,THAP1,SMAD1,EGR2,H2AX,EEF1A1,HCFC1R1 |
| 2.343e-07 | -15.27 | GNB1 (G protein subunit beta 1) | protein interactions | 2782 | 271 | 115 | 19454 | 5460 |
GNB3,CCT7,EGLN3,ATXN10,TCP1,XPO1,GNG11,MRGPRX1,PFDN5,PIK3R1,PSMD3,PIK3CG,AKT2,GNA11,HSPD1,PFDN1,TRIM37,KCTD17,VDAC1,TRIM26,GNG3,MED9,GNG13,RAF1,GNAQ,EZH2,SEC61B,CYB5R3,LMBR1L,GNG12,VDAC2,MAD2L2,ESR2,CUL3,MYC,ACO2,CDKL2,CCT2,PMAIP1,NMRAL1,GNGT2,HDAC5,HACD1,HSPA8,EXD2,DUSP9,DDX39B,GNB4,ADRB2,GABBR1,PPP1CB,VAPB,COX4I1,HACD3,CD274,MDM2,COPS5,CD81,GNG2,HDAC6,MOV10,RGS6,HSD17B10,NTRK2,GNG5,ABCE1,HAPSTR1,FKBP8,GNG10,PSMB9,RAP1A,CCT5,GNAI3,RNF8,NUPR1,VAC14,DISC1,TFCP2,PIK3CA,GNAO1,METAP2,SCAMP2,CCNF,VIRMA,GNAI2,SMURF1,KCNJ3,NDN,AR,PPP1CC,USP14,ATP5F1A,CARS1,AKT1,UBE2H,NRP1,MAVS,SQSTM1,PRKCB,SYVN1,BAP1,SOD1,RPA3,HSPA5,RASD1,CDC42,COMMD3,PAQR3,ATG16L1,PDCL,MET,FGFR1,SAMM50,GNG7,RPA2 |
| 2.383e-07 | -15.25 | SEC63 (SEC63 homolog, protein translocation regulator) | protein interactions | 11231 | 332 | 136 | 19454 | 5460 |
G3BP1,EMC8,ZC3H7A,GPM6B,SCD5,CYP2C9,ARGLU1,TMT1A,RINT1,TAPT1,RPL18,PLD3,STK16,RPN1,STIM1,YIPF3,DNAJC25,MACO1,MARCKSL1,RAF1,STBD1,ARFGAP1,EMC10,RPS10,STX5,RAB35,DUSP6,RB1CC1,CDK5RAP3,DDRGK1,QPCTL,SEC61A2,PTDSS1,STX7,UFL1,EMC1,RAB5A,EP300,AKAP1,DUSP9,DNAJC3,TMEM106B,ATP5PO,VAPB,SEC62,OTULINL,TMEM231,TOR1AIP2,BET1,PGRMC1,ATP6AP2,ESR2,REEP4,RMDN3,SEC61B,LMBR1L,RPS5,SCFD1,SPCS3,FAS,LMNB1,IRF1,VEZT,MYC,GPBAR1,CDKN3,POLE4,FKBP8,CACNG3,DNAJC30,SRPRB,RAB3B,TGFBR2,SLC16A1,LPAR2,IGF1R,EMC2,LBR,PREB,CCDC47,ATP5PB,TBK1,TP53,TMPO,LMAN1,ATP5PD,SPPL3,FZR1,ARF6,DNAJC1,HSD17B11,FA2H,SRPRA,HACD3,SRP14,STT3A,PTPN1,CAMLG,OSBPL8,ESYT1,HM13,TMEM199,EMC4,SLC25A46,TOMM20,CLDND1,HSPA5,YKT6,RPL4,SYVN1,RAB9A,DERL1,RTN4,MTDH,TEX264,RPA3,LEMD3,LMNA,RPA2,SLC12A2,FGFR1,SSR1,TRAM1,ST7,RABL3,SEC22B,TECR,VIRMA,EIF4H,RPGRIP1L,SEC61A1,CALU,HMOX2,C9orf72,GSTK1,VAMP5 |
| 2.385e-07 | -15.25 | HDAC4 (histone deacetylase 4) | protein interactions | 9759 | 397 | 158 | 19454 | 5460 |
RPS12,UBE2I,TRIM27,CDPF1,ENO1,STUB1,VIRMA,NR1H2,AR,CEP70,RPS17,ATP5F1A,FAM110B,NUDT4,SMAD2,BICD2,FAM53C,PGK1,RPL27,UGDH,HSPA5,BCL6,LDOC1,MEF2A,HMGB1,RPS15,HDAC3,SIPA1L1,SUMO1,RPS14,ACACA,IFRD1,AGAP1,CDR2,TFIP11,HSP90B1,EIF4E2,CDR2L,SYNCRIP,SDHB,HRAS,SMAD3,CDK9,POLE3,KCTD3,RPS16,SUV39H1,ELOC,TPM3,GAPDH,NFKB1,TNFRSF14,SSX2IP,SHC1,TIAM1,NME2,EIF3E,RPL17,SRSF12,OLA1,THRAP3,HUWE1,EGR2,LBR,EEF1A1,CCT5,KIF1C,RPSA,STARD13,APEH,CAMK1,FOXP3,SNRPD2,NFKBIA,PNMA1,FAU,GNB1,APEX1,FCHSD2,CBX5,CHCHD3,RFXAP,TUBB,RBBP4,STAT1,PRDX2,ATP5F1B,BRMS1,MAP3K21,RAB11A,PSMA4,SFN,IKZF2,PFDN6,DNAJB6,SERPINH1,RPS5,SP1,HSP90AA1,YWHAZ,HDAC5,HSPA8,RTKN,RPS28,DDX39B,TNFSF10,NSFL1C,CDKN1A,ETF1,CD59,RFXANK,PGRMC1,INPP5E,SYK,CSNK1A1,SLC25A3,NDUFA5,CTBP1,PPARG,RFX5,RPL9,SIN3A,NUP35,HSP90AB1,ANKRA2,CACYBP,SUMO2,HNRNPL,CTNNB1,YWHAG,HNRNPA1,YWHAH,MAP1S,GSTM3,PDIA3,YWHAB,CAMSAP2,HSPB1,BCL2L1,AGR2,PPM1B,TESK2,BAG2,CDK5,RUVBL2,PICK1,ATF3,RINT1,MORC2,MEF2C,HSPD1,RPS27A,PFDN1,S100A10,ZBTB16,ACTN4,PPP2R1A,EZH2 |
| 2.385e-07 | -15.25 | SRSF7 (serine and arginine rich splicing factor 7) | protein interactions | 6432 | 397 | 158 | 19454 | 5460 |
ARGLU1,SRSF8,MRPS11,EWSR1,HNRNPF,RBBP7,TNF,TFPI,KRAS,COPS4,PPWD1,E2F4,RAF1,B3GNT2,EZH2,SKA3,SNRPE,ZRANB2,SRSF1,FOLR1,HP1BP3,EED,SNRPD3,BUD31,SNRPA1,DHX15,SRSF10,WWP2,MRPS35,DDX50,TRA2A,EIF3D,DDRGK1,MRPL9,HNRNPA1,XPO1,SKIC8,MRPL18,DDX23,MAGOH,VPS4A,RB1CC1,MRPS26,DDX39B,NGRN,EP300,HSPA8,NMRAL1,EEF1G,STAU1,UFL1,TRA2B,ATP6V1G1,MRPS7,SAP18,ZC3H14,ELK4,MRPS18A,USP39,NCOA5,MRPL13,SNRPD2,SNRPD1,RPL35,SNRNP40,MATR3,ESR2,IREB2,CUL2,HNRNPC,GRB10,MYC,APOBEC3B,SNRPB,BTF3,MRPS25,DCAF4,ATG3,RIT1,COP1,NKRF,SNIP1,MRPL52,DHX9,MRPS18B,SEPTIN7,VRK1,THRAP3,CDC40,NEDD8,MRPS33,MRPS18C,MEPCE,KIF1C,FBP1,IK,SURF4,NUPR1,MRPL51,ILF2,ALYREF,MRPS9,CDK6,MRPL50,CAND1,FZR1,MRPS23,CDC5L,DKC1,CDK9,TMPO,MALSU1,MOV10,DPP4,APOBEC3F,HDAC6,COPS5,CHCHD1,SNRNP70,DDX46,RNF113A,CLK1,TWNK,FBXW7,HMGB1,RBM22,MRPL17,RPS15,MRPL20,LIAS,SF3A1,CPSF4,METTL14,ZNF326,SDCBP,MRPS34,LUC7L3,TFIP11,ZNF574,ENO1,EIF4A3,SF3B6,CCNF,PTEN,PRKRA,PHAX,MRPS28,NDN,SRPK2,DYRK1A,PPP1CC,USP14,FBXO7,RC3H2,CASC3,UBE2H,PPIG,PTTG1 |
| 2.387e-07 | -15.25 | RHOJ (ras homolog family member J) | protein interactions | 57381 | 628 | 234 | 19454 | 5460 |
FLOT1,AHCYL1,ACVR1B,JAK1,SLC39A7,SCYL2,STX12,ITGB5,STIM1,VPS33A,RPN1,PCDH17,TULP3,IFNGR1,LGR4,PPIA,TMEM237,RAB11B,OCRL,SPTAN1,GJA1,NEO1,WDR6,PHB1,MRTO4,RAB32,PIK3R1,STX7,CXCR4,ATP2C1,SLC25A3,EHD1,ETF1,NOTCH2,DAAM1,TOR1AIP2,CHCHD3,LRRC8A,AP2M1,FAM177A1,SLC7A11,CNIH4,ILK,VMP1,YWHAZ,MRPL16,TOMM40,NIBAN2,PKP4,RPS13,ADD2,SLC25A32,WASL,SNAP23,HSD17B10,LTBR,RAB1A,STX8,NSDHL,EHD4,DLG1,SFXN1,DHRS7B,CASK,ZDHHC8,KRIT1,LBR,SLC29A1,TMEM126A,CMPK1,CAV1,C2CD2,CDCA3,EHBP1,OSBPL8,SLC2A1,TIAM1,ESYT1,RAB23,CDC42SE2,DAG1,ATP1B1,RELL1,BMPR1B,ATP5MG,UQCC3,CDC42EP4,NF2,YKT6,PDHB,B2M,EIF5B,SLC7A1,PIK3R2,SQSTM1,MET,CTDSP1,JUP,PAK5,STOM,PICALM,SLC12A2,CNP,PDE8A,PIP5K1A,SEC22B,ARHGAP1,SNRPN,SH3BP4,UBB,FERMT2,GNAI2,RPL13A,SNX3,YES1,SLC11A2,GANAB,RPS12,VAMP3,GAB1,CTNNA1,LRP6,EPHA2,SMAD2,DEPDC1B,VAMP8,RAB18,PAK6,SLC20A2,ROCK2,CDK5,EFNB1,GNA11,TOP2B,HGS,PTRH2,KDELR1,TMEM59,MFSD6,VAMP7,GFOD1,SPINT2,RAB35,PTK7,YWHAB,ARHGAP5,DRG2,YWHAH,PPFIBP1,YWHAG,OLR1,CTNNB1,UTP6,TBC1D5,WWP2,RAB5C,PTDSS1,GNB4,ITGAV,PACSIN3,ABCC5,EMC1,BMPR1A,PAK2,UBAC2,IL6ST,USP6NL,TAMM41,RRAS2,FAM83B,MTG1,SLC38A1,SLCO3A1,LAMTOR1,PSMD1,RALGAPA2,SLC1A3,SLC6A8,RDH11,AKAP12,NEDD8,CSE1L,SRPRB,SLC16A1,ABCE1,PALM2AKAP2,SLC25A11,BHLHE40,UGCG,CERK,GNAI3,EXOC3,TFRC,BMPR2,ACVR1,SNAP29,LMAN1,STX6,TMPO,SLC38A2,VTI1B,FCHO2,FLRT2,RAP1B,ADD1,SLC39A10,STT3A,ITGA6,NUS1,SMAD4,SLITRK5,NOS1AP,RAB9A,DERL1,ITM2B,ARHGEF6,LRP10,TFB1M,GIT2,LEMD3,SDCBP,CDC42,SPTBN1,ROCK1,RALA,STX10,UQCRC2,NECTIN2,ATP1A1,ATP1B3,ARHGAP21,SLC6A6,RAB2A,SLC25A1 |
| 2.410e-07 | -15.24 | cellular homeostasis | biological process | GO:0019725 | 689 | 264 | 18204 | 5365 |
TXNRD3,CNR1,ATP1A2,SLC8A1,CARTPT,SOD1,PICALM,FIS1,ATP1B1,PLAA,NDFIP1,FRRS1,BAG3,ERO1A,RGN,MIR320A,GRIA1,SLC30A7,XBP1,SLC4A8,NUCKS1,CCR1,PRKCB,EGLN2,LACC1,CAV2,GNB3,ATP2B4,MT1E,DRD3,SELENOS,SMAD4,SLC31A1,PRND,ACO1,FTHL17,GLRX2,ATP6V1G1,PPP3CA,GCLC,ATP6V1C1,P2RY4,GPX1,MT3,TF,VDR,RHAG,BAK1,TXN,ATP5F1B,GSTP1,TXNRD1,TWNK,SLC1A1,BOK,CALR,ATP6V1G2,IL1A,CHP1,UCP2,MIR146A,PSEN1,MTM1,TXNRD2,DNAJB2,ATP2C1,UBE2S,AQP11,CCDC186,SLC39A9,IDE,AQP4,ATP1A3,FXN,NPTN,SLC38A3,MCL1,SMAD2,RTN4,PCK2,ORMDL1,MSTN,IREB2,CAV3,KCTD17,CHMP2B,CMA1,TPT1,BAP1,SNAPIN,FKBP1B,EDNRA,FTL,PAX6,SIN3A,PRDX4,ATP6V1A,IFNB1,CAV1,SLC1A3,RNASEK,ATP6V1D,E2F4,GRM1,MT1X,OXSR1,PRNP,TRPC1,ATP6AP2,HTR2A,CA2,CNNM4,VPS33A,CCL3,KCNJ2,FTH1,PRDX3,CFL2,IL6,IGF1R,LAMP2,SLC6A2,MYC,ATP1B3,BAX,UBE3A,UBE2K,RMDN3,NELL2,KCNB1,CCL5,ATP6V0B,STOML2,FITM2,NPTX1,SLC25A27,CCL19,VPS54,BOLA2B,F2,CCR2,SLC29A1,GRM2,MT2A,BOLA3,SLC12A2,PLN,CFTR,DMPK,TMEM203,LRRC8D,ADNP,SRI,SLC22A12,GPR89A,ANKH,MIR16-1,CACNB4,BOLA1,TRA2B,MT1M,HSP90B1,PML,CCL2,GLRX5,SLC11A2,DISC1,CLCN6,NPPC,NHERF1,TASL,SMDT1,SELENOT,AGER,SLC22A17,PLG,S100A8,FBXW7,FOXA3,PRDX6,CCL23,TMBIM6,CD40,KCNMA1,RAB11B,CXCL12,HFE,ORMDL3,COX19,TFRC,TRIM6,SELENOK,TMEM106B,CLTRN,ATP1A1,TRIM32,CYBRD1,PPT1,CX3CL1,ISCU,ATP6V0E1,SLC39A10,SMAD3,RAF1,VAPB,SLC7A11,STC1,FUNDC2,FATE1,CCDC22,STIM1,CYP7A1,SV2B,OPRK1,CCL1,SLC30A5,PIK3R2,NQO1,CCDC47,PIK3R1,CHRNA7,SLC41A1,HEXB,B2M,MIRLET7G,TMEM199,ALPL,MAIP1,FGF23,NFE2L2,MT1A,SLC4A10,CYB561,DDIT3,FASLG,LRRC8A,KRIT1,TMEM165,ATF4,TM9SF4,SLC25A23,CCL8,COX11,CCL11,LARGE1,CIAO3,ADORA1,PRDX2,P2RY1,KCNJ11,PRDX1,MIR15A,SLC39A7,SOD2,NEO1,RHCG,APEX1,SNX10,CLIC4,ICAM1,ARF1,SLC39A13,PIK3CA,CACNB2 |
| 2.436e-07 | -15.23 | TRAP1 (TNF receptor associated protein 1) | protein interactions | 10131 | 442 | 173 | 19454 | 5460 |
CFL1,PRKACB,NDUFAF2,RPL7A,CCNB1,OAT,UBE2H,MRPS28,PTPMT1,RPS3,SMURF1,KCTD9,HEXIM1,UBE2M,RPA2,QRSL1,SAMM50,IDH2,GFM1,BAP1,DDX46,GRPEL1,HSPA5,NME4,GAPDH,TPM3,LYPLAL1,RBM17,TRMT5,SMAD4,EXT1,MRPS9,SSBP1,COX4I1,UBE2N,MGME1,ESD,TLR6,TLR1,CDC5L,HADH,H2AX,GLRX5,ATP5PB,CDK4,TFCP2,CLPB,IDH1,THG1L,MAP1B,ATP5PF,PDE12,AKAP12,TGFBR2,SNRPB,MYC,COX6B1,MCPH1,VDAC2,TACO1,DLST,CCDC90B,ESR2,APEX1,ATP5F1B,ISCU,EDEM3,MRPL12,LAP3,SF3B1,HDAC5,NDUFS2,EEF1G,RER1,STAU1,OXCT1,PHB2,NDUFV2,AK2,AGR2,MAGED2,GLRX,PNPLA8,LYRM2,SOX2,ISG15,KIF2A,CRKL,HGS,PLS3,PDHA1,CDK5,PAX6,KGD4,VDAC1,RUNX1,ATP5F1A,DNAJC8,PYCR2,ACAT1,CCNF,VIRMA,NDN,RHOJ,CDK7,PCK2,SF3A1,PSMC4,ATG16L1,MYL12B,CDK1,METTL14,RTN4,RPA3,SOD1,POLDIP2,EIF5B,GRSF1,PTGER4,RB1,TES,DBT,CDK9,MRPL24,EEF1A1,PPIF,TNFAIP8L1,NDUFS3,HSD17B10,SFXN1,FASTKD5,ABHD10,HSPE1,ACO2,AUH,CUL3,TXNRD2,PYCR1,ENO2,MAD2L1,NDUFAF4,SNRPB2,ACTB,IDH3B,RPE,ATP5IF1,HADHA,HSCB,ZNF207,PDIA3,CLPX,STOML2,MRPS35,MRPS26,RHOG,FOLR1,PHB1,DHX15,RAF1,HSDL2,EZH2,VAMP2,CHMP4C,NDUFS6,HINT2,COX8A,HSPD1,PREPL,SLC25A5,MRPS17,RAD21,UFM1,ETFA |
| 2.450e-07 | -15.22 | ERBB3 (erb-b2 receptor tyrosine kinase 3) | protein interactions | 2065 | 338 | 138 | 19454 | 5460 |
GABARAPL1,RPN1,STIM1,MTMR2,EIF1AX,HGS,CRKL,SLC25A5,HNRNPA2B1,CDK5,FHL3,CHN2,HNRNPF,S100A10,MRPS17,RPS27A,TFG,PIK3R1,SHC3,ZNF207,FAM241B,HBA1,NCK1,PPM1B,MRPS26,POU5F1,PPM1K,RPL23,TMEM14A,SH2D1A,YBEY,TRIR,UQCRH,HSP90AB1,DUSP14,MTMR6,SYK,HSH2D,BEND5,IL6ST,VAV2,VAPB,HBE1,FKBP1A,HSPA8,SLC31A1,SAP18,STAP1,RNF41,HNRNPAB,PIK3R3,SOCS5,YWHAZ,CHTOP,MRPS25,PFDN4,PDF,PFDN2,SCFD1,HSP90AA1,SLA2,ACTB,TVP23B,TUBB,SNRPB2,JAK2,TP53,SELENOK,SOCS3,PIK3CA,GRAP2,MAP1B,DDR1,TCEA2,ERG28,MRPS18B,HINT1,PSMA5,L1CAM,EGR1,SOCS2,DUSP21,VTA1,PTGES3,DUSP19,LAMTOR2,SNAP91,HDAC6,SHC1,FGR,ITK,SRPRA,AIFM1,ACTA2,RPS27L,MDM2,LCP2,MRPS23,TXNL4A,DUSP18,NDUFAB1,GABARAPL2,TCP11L1,MRPS34,JUP,FGFR1,HBB,GOLGA5,SSR1,HNRNPH3,MET,INPPL1,HNRNPH2,RTN4,B2M,USP8,PIK3R2,HSPA5,CSK,AKT1,PTPN11,CFL1,ATP5F1A,TUFM,PPP1CC,CHCHD4,SF3B6,TUBA1B,TMA7,PPM1M,PRSS8,MRPS28,PTEN,TXN,YES1,SRC,DYRK1A,SRPK2 |
| 2.469e-07 | -15.21 | ASPH (aspartate beta-hydroxylase) | protein interactions | 444 | 303 | 126 | 19454 | 5460 |
FGFBP1,SFXN2,SLC1A1,STX10,VAMP3,UQCRC2,FBLN5,CHRM5,VIRMA,DYRK1A,KCNIP3,RNASEH1,SLC25A4,NTAQ1,FBXO7,HMOX2,TUFM,NAPA,ATP1A1,UBE2H,CALU,SPOP,RC3H2,SYVN1,SQSTM1,RPA3,TMX2,WFDC5,PIP4P1,HSPA5,PDHB,TMEM167B,FBXW7,UQCRC1,FTH1,TIMMDC1,CYC1,RPA2,STX17,NELL2,SRPRA,MGME1,CDK9,STX6,PLEKHF2,RPS16,VTI1B,CGAS,EI24,CALR,FAM20C,SMDT1,IL21,POR,BGLAP,SNRNP70,SOD3,STX18,EMC2,BCAP29,LTA,STX8,SMIM11,TGFBR2,CLEC2B,CCDC47,TP53,FAM162A,GPX7,RELL2,NDUFS3,RETREG3,SEC61B,LMBR1L,ESR2,ATP5F1B,OST4,MYC,CUL3,TM9SF4,TAFAZZIN,ATP1A3,RAB5A,HADHA,SLC35F2,TMEM160,TMEM106B,EXD2,CDSN,STX7,SLC37A4,UFL1,PTN,HSCB,CMTM6,NOTCH2,VAPB,SDC2,SIGMAR1,ATP6V1A,DEFB1,MPDU1,VAMP7,NDUFS8,UQCRH,HNRNPL,NDUFV2,MAP3K14,FAM241A,DDRGK1,WWP2,SEC61A2,CBL,AGR2,COX8A,SMIM19,EMC8,SOX2,GTF2E2,EEF2,RAF1,E2F4,STX12,MOB3C,CTSA,PDHA1 |
| 2.469e-07 | -15.21 | EBNA1BP2 (EBNA1 binding protein 2) | protein interactions | 10969 | 303 | 126 | 19454 | 5460 |
KRR1,SYNCRIP,SRP14,RB1,ARL4D,TES,CAND1,RPS16,FZR1,KLF9,ZBTB2,SURF6,TMPO,EMC4,GRSF1,API5,COPS5,SNRNP70,CHCHD1,H2AC4,MPHOSPH10,NOL12,SNIP1,RPL3,H3C1,RPL17,TP53,MRPL11,RPL15,RBM34,NUPR1,RNF8,HBP1,ZNF330,EIF2AK2,CCNF,GSK3A,PRKRA,RPL13A,ZNF622,SRPK2,SMURF1,RPL7A,RPF2,PPP1CC,CEP70,RPL26,RC3H2,UBE2H,RRP7A,SIRT7,NLE1,RPA3,SNAPC1,RPL27,MTDH,RNF113A,FBXW7,RPL4,NPM3,AATF,BRIX1,CFTR,KLF12,GRM2,METTL14,RPA2,CDK1,MACROH2A2,RPLP0,MRTO4,SRSF1,RPL8,EED,RPL7,LYAR,NOP58,DHX15,RPL6,WWP2,IFI16,MAP3K14,DDRGK1,WDR12,DDX23,LHX2,DRG1,FGF3,RPL31,RPS24,H1-6,SRSF4,RPL28,RAF1,MAK16,SOX2,HDAC11,RPL18,MTMR2,RPS9,RPL37A,SNRNP40,PSMD6,RPL10,APEX1,CUL3,GRB10,MYC,BTF3,THAP7,FTSJ3,BRCA1,DCAF4,ARHGAP19,RIT1,DNAJB6,NSA2,H1-1,EP300,HSPA8,NOP53,STAU1,SAP18,SYK,RPL27A,ADNP |
| 2.469e-07 | -15.21 | VAMP3 (vesicle associated membrane protein 3) | protein interactions | 9341 | 303 | 126 | 19454 | 5460 |
LMAN1,STX6,AIG1,CAV1,VTI1B,RPL35A,ARF6,EIF2B2,HSD17B11,LHFPL2,CD4,LMBRD1,RAC2,PTPN1,HRAS,COMT,STYK1,SLC2A1,MED21,ESYT1,LAMP3,CD81,LAMTOR2,PLEKHO1,STX11,PSEN1,RAB3B,SLC16A1,BSCL2,STX18,MLC1,SNAP23,PTGES,RAB1A,STX8,VAC14,TFRC,TMEM31,MAP1LC3B,SNAP29,JPH4,CENPM,MGST3,RAB14,RHOJ,STX10,VAMP3,SCAMP2,ELOVL4,ATP1A1,NAPA,ATP1B3,DNAJC5,MGST2,RAB2A,VAMP5,NAPG,DERL1,RAB9A,RPA3,RHOU,TMX2,LMNA,RPA2,ZMYM6,PTP4A2,USE1,SNRNP27,CDC42,TIMMDC1,DIRAS3,VAMP7,TMEM237,RAB11B,RAB1B,RHOH,GJA1,NRSN1,ATP6V1A,RAB35,STX1A,TMEM30A,PDZK1IP1,RHOG,LAMP2,MTRF1,RAB5C,FAM174A,VAMP8,CPLX1,KRAS,COX8A,RINT1,TMT1A,SYPL1,RND3,STX12,ENPP4,MOB3C,VAMP2,ZC4H2,RAB4A,ATP6AP2,MANSC1,RETREG3,RMDN3,SEC61B,FIS1,LAMTOR1,RHOB,STX16,TM4SF19,TM4SF20,SCN3B,RAB11A,STX7,RNF11,GOSR1,RAB5A,BET1L,PMAIP1,VSIR,RND2,DUSP22,PTAR1,BET1 |
| 2.481e-07 | -15.21 | Regulation of DNA replication | REACTOME pathways | R-HSA-69304 | 77 | 46 | 10285 | 3229 |
PSMA1,PSMC3,CCNA2,PSMD4,MCM3,RPS27A,PSMB4,PSMD6,PSME2,ORC6,SEM1,PSMB9,FZR1,PSMA6,PSMB2,PSMD1,CDKN1A,MCM8,PSMC1,PSMD12,GMNN,PSMD14,RB1,UBB,UBA52,PSME1,PSMD10,PSMD7,PSMA5,PSMB10,PSMB11,PSMC5,PSMA4,MCM4,PSMB3,PSMA2,PSMB6,MCM6,PSMB1,PSMB7,PSMD3,ORC5,PSMC4,CDKN1B,PSMB5,PSMA3 |
| 2.482e-07 | -15.21 | RBFOX2 (RNA binding fox-1 homolog 2) | protein interactions | 23543 | 277 | 117 | 19454 | 5460 |
MIR200C,BCS1L,MIR17,VAC14,RNF8,MIR200A,RPL3,MIR9-3,TOLLIP,APH1A,HNRNPK,RPS13,MIRLET7C,MIR16-2,SMN1,RIGI,RBM17,RBFOX3,SPATS2L,PPIL4,APOBEC3F,MIR34A,SPMIP9,MIR25,GATAD1,MIRLET7G,MIR429,RBM42,SURF6,SF3A1,MIR34B,RBFOX2,RBMS2,RPA2,LMNA,MIR21,MIR7-1,RPA3,RBM23,MIR10B,MIR205,HNRNPH2,MIRLET7I,MIR34C,RPL4,RBM22,MIR29A,MIR107,FBXO7,ST13,SPOP,RC3H2,ELAVL2,MIR16-1,GIMAP4,SFXN2,RBM12,MIR222,SOX2,RBM38,TUBA1A,RPN1,FAM136A,MIR9-2,SDHC,MIR206,HNRNPF,MAPK1IP1L,MIR155,RERE,HMGA1,PDIA3,PRPF19,MIR143,MIR29C,HNRNPA1,MIR31,MIR221,MIR1-1,MIR140,PHB1,BOLL,MIR141,MIR214,HNRNPL,LSM5,MIR9-1,DYNC1I2,PEG10,EGLN3,TRMT61A,TIMM29,LARP4B,SNRPA,RPS28,FAM168B,DDX5,PSMA3,YTHDF1,MIR106A,MYC,HNRNPAB,CUL3,DCAF4,MIR363,PHF12,MTG1,ATXN1L,PRMT5,SF3B4,CDC7,MIRLET7B,MATR3,SNRNP40,PRRC2A,PARL,ESR2 |
| 2.484e-07 | -15.21 | RPUSD3 (RNA pseudouridine synthase D3) | protein interactions | 285367 | 195 | 88 | 19454 | 5460 |
MRPS16,CHCHD4,NDUFAF2,EMILIN1,PYCR2,RHOJ,MRPS28,ACAT1,TFIP11,MRPS34,KDELR2,CDC42,RBMS2,MRPL20,NME4,PDHB,MRPL41,CLK1,DLAT,SNRNP70,GRSF1,DBT,MALSU1,RBM42,MRPS23,MRPL50,PRR3,RAC2,MRPS9,MRPL49,MRPL51,MINDY3,NDUFS3,PPIF,DUSP1,BCS1L,ATP5PB,MRPL47,NDUFA2,MRPS33,NUP107,HSPE1,MRPS18B,ATP5PF,MCAT,MRPS25,RHOB,FBXW11,MYC,PYCR1,NDUFAF4,ATP5F1B,MRPL13,TACO1,DLST,NDUFA5,PRDX3,MRPL12,FTL,MRPS7,NDUFS2,PHB2,NGRN,MRPS26,FKBP4,MRPL9,NDUFV2,HNRNPA1,STOML2,MRPS35,NDUFS8,YBEY,PHB1,NDUFA12,NDUFS6,PDHA1,NUDCD3,RAF1,HSDL2,ETFB,MRPS17,ATP5F1D,ETFA,NUP42,KGD4,SRSF7,HSPD1,PREPL |
| 2.491e-07 | -15.21 | VRK3 (VRK serine/threonine kinase 3) | protein interactions | 51231 | 138 | 67 | 19454 | 5460 |
SOX2,RPS7,EEF2,MAX,RAF1,CCT5,YTHDF2,SP4,TP53,TUBB4B,RPL23A,RPS24,HSPD1,HNRNPA2B1,H2BC14,RPL17,HNRNPK,KCTD17,HNRNPA1,CTNNB1,H2AC14,HMGA1,PRDX1,RB1CC1,ANKRD50,FOXP1,EMX2,RPL10A,UQCR11,RPLP2,RPLP1,RPL12,ALYREF,DHX15,RPS10,TCP1,PRNP,PPP1CB,RPS14,SNRPN,HSPA8,SQSTM1,FOXD3,BANF1,XRCC5,EEF1G,CFL1,FBXO7,BTF3,RPS17,HNRNPC,PSMA4,CCNB1,HSP90AA1,CCT2,NR2E1,BICD2,SNRPD1,CSNK2B,RPS20,IRF2,EZH1,IFI6,TAB1,PRKCE,TUBB,SPINDOC |
| 2.504e-07 | -15.20 | negative regulation of growth | biological process | GO:0045926 | 227 | 103 | 18204 | 5365 |
MT2A,IFRD1,ADRB3,GJA1,TNR,G6PD,GSK3A,MT1M,SERTAD3,DCUN1D3,FGF13,RB1,RGMA,PTEN,NRP1,CDKN1A,ING5,BST2,SPHK2,PML,NOG,EAF2,HDAC6,TRIM46,FBP1,SEMA5A,ADRB2,SERTAD2,MT1E,GREM1,CCAR2,ADIPOR1,SMAD4,DUSP10,STK11,RGS2,MINAR1,MIR25,CDK5,SPP1,SAV1,PLAC8,BCL6,ACVR1B,MSX1,HYAL2,CCN3,CDKN2C,PHB1,ING1,MT3,CRLF3,RBBP7,NAIF1,PPT1,MUL1,TGFB2,SMAD3,FXN,TP53TG5,OSGIN2,DNAJB2,CGRRF1,RTN4,CDKN1B,BRCA1,PI16,SESN2,EI24,CDKN2D,VGLL4,BMPR2,ESR2,CDKN2AIP,CAV3,NDUFS3,MSTN,RERG,SLC6A4,MT1A,MECP2,CYP27B1,ADRB1,MT1X,TMEM196,TOMM70,STK3,PPARA,JADE1,PSRC1,CCDC85B,FRZB,ENO1,SH3BP4,SFRP1,MIR1-1,CRYAB,SOCS2,BTG1,MIR873,FOXP1,TP53,STK4 |
| 2.559e-07 | -15.18 | positive regulation of locomotion | biological process | GO:0040017 | 633 | 245 | 18204 | 5365 |
SWAP70,MIR210,MSTN,NUS1,MIR150,PAX6,CAV1,SEMA4C,ELP6,CLDN1,S100A11,UBE2I,MIR519D,MIR146A,MIR21,FGFBP1,HBEGF,PTN,RTN4,HSPA5,MIR208A,IL4,GLIPR2,CD99L2,MIR31,TACR1,MIR342,IL6,IGF1R,MIR126,CCL17,FERMT2,HSPB1,MMP9,CDC42,SEMA6C,CCL5,GPSM3,FOXP1,MMP14,DUOXA2,MIR200A,EPHA4,DEFB124,AKAP12,FGR,IQSEC1,OXSR1,CSF2,MIR10A,BVES,VEGFC,DAPK3,EMC10,ATP5F1A,CCL3,AKT2,FUT1,MIR132,AKT3,FAM89B,SCG2,IL12A,CD274,PRKCE,CCR1,MIR10B,TWIST2,MIR448,CD151,JAK2,ATP8A1,NRP1,TIRAP,FGF1,ACTN4,MIR221,PLAA,TGFBR2,SNAI2,CRKL,CCL21,MIR20A,MET,XBP1,SOX9,KIT,GNAI2,ATP5F1B,TCAF2,FGF10,DEFB1,CCL24,ADAMTS1,TF,ACTA2,PDCD10,IGF1,CALR,TGFB2,PIK3R3,IL1A,MAP2K3,CDH13,CCR7,SEMA5A,CCR6,SEMA3C,ITGA2,CFAP20,CCL20,PROX1,TNFSF18,WNT7A,PPP3CA,FAM107A,MIR182,IL1B,AKT1,VEGFA,SEMA7A,BMPR2,IL23A,CCAR1,MIR29A,TPBG,NFE2L2,LGALS3,IL34,FZD4,NTRK3,CXCL13,MIR296,SP1,MIR30A,F10,GAB1,PIK3R1,RHOJ,AAMP,CCL1,GPNMB,MIR711,MAP3K3,CLEC7A,TNFAIP6,P2RY12,ITGA6,MIR143,MIR135B,SOD2,TACR3,CXCL8,MDM2,TIAM1,LPAR1,CD47,F7,SDCBP,ARHGAP5,RRAS2,MADCAM1,IFNG,STK4,ICAM1,MIR590,CCL8,ARHGEF39,CBLL1,CCL11,TLR4,MIR939,PIK3CG,THY1,RAC2,ACKR3,ITGAV,FGFR1,ZNF609,ANGPT1,SRC,TERT,DRD1,CCL18,PLP1,CCL4L1,CCL2,TNFRSF14,CXCL10,TMSB4X,AIF1,CCL19,CCR2,FOXC2,CLDN3,ARF6,STAT5A,MIEN1,PRKCA,MIR181D,MIR222,ACVR1,CYP1B1,RARRES2,CCL25,CCDC25,CX3CR1,MIR145,TRIM32,RAB11A,SELENOK,MED23,TNF,VSIR,DDRGK1,XCL1,ROCK2,MIR101-1,CX3CL1,SMAD3,CXCR4,ELP3,HDAC6,TBC1D24,RHOB,GFUS,CREB3,AGER,ZNF304,PYCARD,HRAS,MIR23A,PLG,CCR4,FGF16,FGF7,MAPRE2,HMGB1,CCL23,CD40,BCL6,CXCL12,EPHA2,CLDN4,ACVR1B |
| 2.581e-07 | -15.17 | mitochondrial outer membrane | cellular component | GO:0005741 | 219 | 99 | 19108 | 5553 |
FUNDC2,CISD1,VAMP1,TOMM7,DELE1,HAX1,CYB5A,ARMCX3,CPT1B,SLC25A46,MGST3,ARMC1,BCL2L1,CHCHD6,TOMM20,KRAS,APOO,SLC11A2,MTX2,MIEF1,MTCH2,PPP1CC,BAD,UBB,RAB32,MT3,QTRT2,UBA52,EXD2,IFI27,RAF1,TSPO,HINT2,TOMM6,BAX,SFXN2,RPS27A,COX14,RSAD2,TOMM70,PDE2A,ARMCX1,PGR,SARM1,BECN1,AGPAT5,PTRH2,DMPK,TRAF3IP3,PHB2,MAVS,BNIP3L,MTARC2,MUL1,FATE1,CNR1,SAMM50,TUFM,BAK1,ATP5MC3,DCAKD,FUNDC1,RMDN3,CNP,SH3GLB1,STARD7,MARCHF5,TAFAZZIN,RAC2,CYP27B1,UFL1,THG1L,ACSL4,MGARP,AKAP1,VDAC1,SNN,CYB5B,GK2,TOMM40,SYNJ2BP,USP30,ARMCX2,AGK,BCL2A1,ATAD1,TOMM40L,CYB5R3,VDAC2,MFN1,EPHA4,MCL1,CHCHD3,FIS1,TOMM22,PGRMC1,GPAM,BOK,PMAIP1 |
| 2.610e-07 | -15.16 | PA2G4 (proliferation-associated 2G4) | protein interactions | 5036 | 260 | 111 | 19454 | 5460 |
WWP2,HMGA1,PDIA3,MAP3K14,CTNNB1,DDRGK1,ZNF207,PHB1,RPL8,SIN3A,FOLR1,RPLP2,CETN3,E2F4,RAF1,ZNF263,CHMP4C,PRKAG1,EZH2,PLS3,RPL18,HNRNPA2B1,PDIA6,TRIM37,G3BP1,RPL28,TMED7,RRN3,MYC,ATG101,BRCA1,H1-1,EIF3K,CMTR1,IRF2,FAU,LMBR1L,ACTB,ATP5F1B,RPL10,RPL19,ESR2,SNRPB2,MRPL12,KCTD12,USP39,PIH1D1,EP300,HSPA8,HDAC5,ARHGEF39,G3BP2,NRBF2,MOV10,SUV39H1,HDAC6,UBE2N,RCHY1,CD274,RPL12,RB1,TOP1,RPS27L,RPS16,FZR1,DCUN1D1,MDM2,RBM42,UBL4A,RPL15,DNAJC2,NUPR1,SRP72,DHX9,RPL23A,HNRNPK,RNF20,VAMP5,AKT1,USP14,DNAJC8,AR,PPTC7,UBE2H,MAPRE1,ATP1A1,EIF2AK2,PSPC1,STUB1,TRIM24,UBE2I,EIF2S2,NDN,MYL12B,SF3A1,ATG16L1,RBFOX2,IDH2,RPA2,RPLP0,SH3GLB2,PRKCA,RPA3,BAP1,RPL27,PRKCB,RPL4,FBXW7,EIF5B,AATF,HSPA5 |
| 2.697e-07 | -15.13 | TSC2 (TSC complex subunit 2) | protein interactions | 7249 | 187 | 85 | 19454 | 5460 |
SLC39A9,P4HA2,RAB5A,RAB9A,NPTN,RPL4,RP2,CCND3,RRAGA,CCND1,HCST,CCNA2,CDK1,SERPINI1,PIH1D1,CCNF,ARF1,LMBR1L,CD79B,B4GALT1,RALA,DAPK1,BTG3,APEX1,DYRK1A,AKT1,TMED5,CUL3,MORF4L1,SFN,CCNB1,GPR17,CIAO1,PTPN11,RHEB,LAMTOR1,RHOB,CD226,YWHAZ,SMAD2,IGF2BP1,STK11,RAB1A,CD83,SLC39A7,RUVBL2,PICK1,EFNB1,UBE3A,IGF1R,RRAGB,DNAAF10,SEMA4C,TRIM63,TBK1,TOP3B,B3GNT2,RPSA,RAP1A,EEF1A1,SIGLECL1,TRAPPC13,OTULIN,CYB5B,SMAD3,CBFB,EEF1AKMT3,SPINT2,CAND1,CAV1,LAMP2,MDFI,EDEM1,TSPAN10,LAMP3,YWHAH,YWHAG,GAPDH,MUL1,TRAPPC2L,HAX1,POU5F1,CBL,CDKN1B,YWHAB |
| 2.697e-07 | -15.13 | TRIM26 (tripartite motif containing 26) | protein interactions | 7726 | 187 | 85 | 19454 | 5460 |
PCNA,PSME1,MNAT1,ANP32B,MEPCE,TRIM26,CAMK2G,PSMA1,THAP1,RPS7,SOX2,EEF1A1,SNAP29,TBK1,ANP32A,ZNF263,RNF126,CASK,HBP1,DECR2,PHB1,ANXA4,ZBTB2,MYL12A,RPL7,CGAS,TOP1,SUMO2,CAND1,HNRNPL,CTNNB1,DDRGK1,TPM3,XPO1,PRDX1,IFI16,NQO1,SSX2IP,RPS2,UBE2D1,YAF2,RNF10,SQSTM1,TXNL1,HSPA8,IRF3,EXD2,PYM1,LCA5,UTP23,FBXW7,UBE2D3,ATG16L1,MACROH2A2,STOM,LMNA,USP39,PTP4A2,ALB,MACROH2A1,CHRM5,ENO1,RPS3,DCLRE1C,USP5,ESR2,APEX1,GNB1,RPL35,ACTB,TAB1,LGALS3,LDHA,EIF4H,RPL26,THAP7,RPL7A,CUL3,CREB3,SLC7A11,ZBTB38,PHF7,DCAF4,ARFGAP3,FAS |
| 2.725e-07 | -15.12 | regulation of macromolecule biosynthetic process | biological process | GO:0010556 | 5528 | 1772 | 18204 | 5365 |
FASLG,PIK3CG,HNRNPA2B1,EID1,UQCC2,BZW2,WRAP53,ELK3,IL18,MIR891B,GTF2H2,MIR572,MAGOHB,ETV6,MIR143,STAU1,NEO1,MIR139,PDCD4,CBX7,IFT52,MIR493,TRUB1,CRYM,NIBAN2,ISX,ELK4,MIR218-1,TCP1,H2AJ,MAGED4B,FOXP2,MIR30E,MIR922,MIR24-2,SETD4,NR0B1,CUL3,NR2E1,PIK3R1,RAN,MIR874,CCAR1,MIR652,SLC38A2,BCL9,MIR532,MIR194-2,MIR455,MIR298,MIR769,IL15,MIR137,TLR1,CCAR2,MIR592,MED22,ALKBH4,CREB3,SGF29,HDAC6,INTS12,MIR208B,NME2,FOXA3,MAGEB1,MIR616,CD40,TMBIM6,MED10,ACVR1B,NR1I3,YES1,BIRC2,ASB1,HR,PRKAB1,TNRC6C,ATRAID,TCEA1,SPTBN1,CD2,NIF3L1,VRTN,STAT5A,VIP,RNF26,AKAP8L,RNF10,PTHLH,CYP1B1,TLR2,RPS13,MIR183,MRPL13,HNRNPDL,CCNH,GTDC1,MRPL12,ZNF575,PIH1D1,MIR16-1,WBP2,ZNF805,NUP62,MAPKAPK5,MRTO4,H2AC25,MIR7-1,MAP2K6,DAPK3,MIR607,CARHSP1,SF3B4,MIR589,PRNP,MIR130B,MATR3,FOXN2,UHMK1,HMX1,COPS2,PSMA6,AKT2,SOX21,LSM5,PAIP1,CD86,PYDC2,AGPAT1,TOM1L1,IL6,EFCAB7,MIR379,TRAF3IP2,FCER1G,DDX1,ELF1,MIR223,G3BP2,NKX3-2,DNAJC3,FABP4,CDC73,MEF2B,IFNA2,METTL18,RPL10,MIR580,E2F6,SMG8,MIRLET7D,MIR196B,MLLT6,ADM2,KCNIP3,ORMDL1,TNFRSF1B,PLCB1,TLR9,GTF2A1,MED27,TAPBP,ANXA4,CD80,GABPB1,UCN,FOXS1,NMI,CLEC6A,MIR204,MIR423,ZNF576,ZBTB33,IKZF2,SSBP3,MAD2L2,EIF4B,MIR595,MIR211,TLR6,AGR2,EXOSC8,MTERF2,SLCO3A1,IL1B,ZNF787,DYRK1B,MIR569,AKT1,PPP3CA,CLP1,ELAVL4,MIR182,TOX,CCND3,INPP5E,NEUROD6,CREB3L4,MT3,MXI1,GSTP1,MAX,TXN,TNFAIP3,RBBP4,SKIC8,MIR639,CALR,MIR675,GRSF1,ENY2,WTAP,CNOT2,PTRH2,DKC1,IGF1,MIR604,HMX2,UBE2D1,HNRNPAB,TGFBR2,PHF1,KIT,EIF4A2,MIR1251,MET,MIR320A,MIR631,MIR448,ZNF343,CDK5RAP3,NR1H2,TSG101,E4F1,APLNR,TLR4,ARF4,TGIF2LX,ZBED3,KLF4,RAP2C,CIAO3,SAP18,ZNF574,MIR26B,CRABP2,TRIP4,PCGF2,MIR99B,CNOT8,ZC3H7A,ASCC1,PCGF6,ZNF362,NEK7,SOD2,SOST,EPOP,MAEL,CIAO1,MIR671,ACTL6B,APOBEC3H,EPCAM,MLF1,MIR212,MIR503,SUFU,RHOG,MLF2,SUV39H1,IMPACT,KLHL22,PLGRKT,HELLS,GTF2I,TCEA2,PRIM2,EIF2B2,LHX2,B2M,IFRD2,RPS26,TRIM44,RBCK1,HMCES,C1QTNF1,HINT1,ZNF668,MIR638,LUM,RNF139,IL1RAP,MZB1,TCF19,ZNF511,LURAP1,MIR1296,FBP1,HINFP,ITGB8,ELAVL2,EMILIN1,MED11,HFE,PFDN5,CTDSPL2,BCL6,SH3BGRL,HMG20A,SSU72,ORMDL3,TOP2B,EDA2R,PDE12,RUVBL1,MIR191,CDK8,SF3B1,RBPJ,XCL1,NAB2,BRMS1L,MIR9-2,TNF,SHMT1,HMGA1,ACTB,TWSG1,FGF3,NEUROG2,FOXC2,AIF1,MIR764,CNTN1,RBM38,PAIP2B,CEBPG,MIR17,GJA1,RNF141,CITED1,RB1,TYMS,NAB1,MIR338,PHF12,SDR16C5,RBM5,DRGX,NDN,CDK9,RIOX2,NFYA,SRSF12,BARX2,IL6ST,GTF2F2,BTN2A2,STOX2,RFX4,CSF2,LILRB1,CCL3,ID1,YWHAH,PPIA,MAGEH1,SFRP1,RTRAF,CSNK1E,RBM12,MIR7-2,PELP1,ZNF821,MIR942,MOSPD1,DEFB124,MIR605,EPHA4,MIR200A,ZNF322,CD81,TULP3,NLRP9,ZNF436,MIR149,CD46,TAF5L,NPTN,MYD88,SOCS5,IL20RB,HSPA5,BEND6,TOX4,RPS9,FURIN,KANSL3,MAVS,ZBTB17,MIR760,MIR661,TYROBP,FASTKD5,MIR876,HCFC2,ZNF345,BHLHE40,ZNF501,MIR1226,ISG15,THAP7,UAP1,SPP1,MIR25,RABL3,DHX9,MIR30D,MSL2,MIR517B,TRIM8,TLE1,LTB,MIR597,NEDD8,MIR370,RLIM,MIR449B,MIR346,MIR215,DLG1,IGBP1,SF3B5,CNOT6,IKZF5,DNAJB9,BANF1,DICER1,ZCCHC7,TOPORS,STAT2,MIR429,EXOSC4,RGN,MIR551B,SUB1,IL1R2,ANKRD49,MIR488,HGS,PRMT2,MAP2K1,HDAC5,MIR511,PPP1CC,MIR936,TOB2,STPG4,KDM1A,BUD23,TSN,TLR7,ZBED1,MIR29C,RGMB,EDF1,IL5,SQSTM1,LEP,COMMD6,POLR2G,MIR601,CD200,ZNF175,TCOF1,PHB2,MIR148B,PIWIL3,ZNF740,EIF1B,SMARCA5,MIR765,STK16,HOXB8,MIR7-3,MED17,MIR873,MIR34B,EIF2B5,EIF4EBP3,MIR153-1,RFXANK,EIF3K,CCDC3,MIR563,MIR618,MIR296,MYT1L,CIPC,TLR8,NTRK3,ZNF319,BRMS1,TRIM3,MIR100,MIR625,GTF2IRD1,SRSF4,TFE3,SEMA7A,MIR549A,DRAP1,SMARCB1,BMPR1A,SOX3,NFE2L2,DNAJB4,PRMT6,MPV17L2,PKNOX1,RPS7,NFKBIL1,NKX3-1,MED30,OTULIN,MACROH2A2,MIR23B,CLU,TFRC,ELOC,PNRC1,MIR920,SERPINB1,TUSC2,CRTC2,MAGEB10,NR2F6,PCBD1,H2AZ2,SFTPD,TLR5,ZBTB25,NDP,FKTN,FXR2,GADD45A,NEK2,CD38,CD2AP,PABPC1,MIR491,SNAI3,TERT,MIR141,EIF2S1,PML,HCLS1,TFCP2,BMPR1B,IFNGR1,RXRG,PELI1,PPARA,NEUROD2,ZNF263,MIR10A,DMAP1,ENO1,LDLR,HAS3,PRL,TRIM34,MIR186,JUNB,OTX2,BTG1,ZNF267,RFX5,CSK,MIR633,GTF2F1,ERP29,RNASEL,LDB2,FGR,THRAP3,ECD,CKS2,MIR21,ANAPC2,ELP6,WDR82,CPNE1,CREBL2,NGDN,SYNCRIP,MIR330,DNM2,IREB2,TCF21,DXO,FOXD3,SRSF10,CD36,RBBP9,MIR129-1,BAP1,MED29,IFI27,PC,SMAD4,INO80E,RNF128,LSM4,MIR938,NOP53,MIR578,EID2B,MIR1271,UBE2V1,TSNAX,H2AC7,KLK5,SHLD1,HYAL2,MIR1227,SP2,CTNNB1,KARS1,EIF3D,NAA16,MAGOH,PDCD10,MIR384,DR1,SNX5,NCOA5,MIR497,RRN3,CARTPT,SLC8A1,UBE2N,MIR155,MIR221,PSMC3,SS18,RLN2,EIF2AK2,CD14,LMO4,GRIA1,RIOK2,TNFSF13,MIR377,CREBZF,CD34,SMCHD1,RAB27A,ABCE1,DEFB114,CRY1,LACC1,DVL2,LRP6,STAT1,USP3,CAND1,LMO2,PTEN,MCPH1,JAK2,MORF4L1,MED31,FBXL19,MIR500A,DDIT3,MIR586,DNAJC2,POLE3,MIR590,SMG9,TOMM70,ADORA3,SIX5,FGF22,NKAP,MIR340,P2RY1,SRSF1,UBE2D3,ATG101,UBP1,ITGA6,MIR770,FKBP8,CXCL8,MIR133B,MIR30A,CCDC22,PPARG,EMX1,PGR,ZNHIT1,SESN2,MIR106A,SLA2,PRKCQ,F11R,MIR193A,UFD1,EZH2,UPF3B,CHRNA7,MIR554,NFYB,MIRLET7G,NCSTN,EIF4H,YTHDF2,MKKS,IL34,IKBKB,MIR422A,EGR1,ZNF664,EPO,MNAT1,NR4A2,MIR28,HRAS,PYCARD,GABPA,GTPBP1,MIR875,HNRNPH3,LBX1,RGS2,SSBP4,HMGB1,BCL7B,LY96,CX3CR1,MIR145,ZSCAN5A,MSX1,TRAF1,TAGLN3,NKX6-2,RFC5,STN1,PTGFR,MIR611,IL10,MIR640,FERD3L,ARMCX3,RAF1,SRSF2,MIR505,NAA15,RBBP7,CRLF3,POLDIP3,DDRGK1,MIR636,BCL7C,PLSCR1,CCR2,F2,POMT2,ACVR1,EIF4E2,PRKCA,BRD3,ADNP,DAP,CGAS,TRA2B,ZBTB45,NFE2L1,BHLHA9,APOBEC3B,USP16,RFC4,ZNF593,INPPL1,CTDSP2,TNFSF8,NFIL3,MED21,EED,MIR557,OSR2,RPS6KA4,MIR194-1,ATP6AP2,CDK1,SNIP1,DDT,APOBEC3D,PDCD5,MIR105-2,MARS1,MIR142,MIR490,HSPB1,DAPK1,MIR126,MIR553,MIR184,MYC,LRRC14,DLX1,SSBP2,ITM2A,GPSM3,MIR106B,CASK,TNKS2,PSEN1,CD4,ZHX1,SNRNP70,ZNF687,MIR324,UBE2I,APOBEC3F,BUD31,MIR31,SLC38A3,BRCA1,ALKBH5,MIR342,SMAD2,IRF9,ZNF397,RBM22,SUPT7L,RAB1A,PIM2,MEAF6,MTG1,TNKS,RBFOX2,CAV1,IFNB1,RBBP8,PPP1CB,MEPCE,MIR147B,ZBTB18,PROX1,CREBBP,TNFSF18,MIR152,KLK3,ZNF177,DYRK1A,WASL,GCLC,NCK1,IRF6,IL2RG,TF,FGF10,IL1A,PPP1R3C,DPY30,KRAS,PICALM,LITAF,PYM1,AIP,MTF1,TRIM22,MIR656,DIRAS3,OAS1,SETD3,TWIST2,HNRNPC,COPS5,SUMO1,CDCA7L,FOSL2,LTA,ZBTB26,XPO5,ACTN4,ZSCAN1,MIR1260B,IRF7,NLRP6,SMAD1,CCT2,MIR200C,MIR425,CD40LG,MIR939,TFEB,MIR140,PDE4B,CD58,CCDC85B,RB1CC1,KLF3,H1-3,MIR15A,PHAX,SUPT4H1,ROCK1,APEX1,ZC4H2,IL17F,TAF10,CD47,PIK3CA,TAF1D,CAMK1,KRBOX4,FZD4,CAPN2,DEK,SOX14,OSM,YWHAZ,CCL1,PRKACB,MIR301B,PIK3R2,KLF1,MIR944,SATB1,ZNF704,VEGFA,MTA2,CLK1,IL23A,PPM1B,EIF3E,FGF23,MTPN,NUDT16,NSMCE3,SELENOT,MIR129-2,TRIM5,MALSU1,APOBEC3C,EWSR1,EAF2,PRR5L,S100A8,TESC,NOG,PRDX6,FBXW7,BOLL,HNRNPL,NLRP1,HILPDA,PITHD1,FGF16,SYK,CNOT6L,RASD1,SERTAD1,MED23,LAMP3,ZSCAN25,MAGEA4,MED9,TRMT112,UBE2L3,GPAM,TRIM32,MIR101-1,VSIR,MIR363,APBB3,CDK4,MIR32,MIR632,ZBTB39,XRCC5,TBK1,CYRIB,PIAS1,VAMP3,ZNF287,TACO1,MIR373,H2AC1,APOBEC3A,C1D,SERTAD3,CIART,PDE2A,DNAJC1,POU1F1,RBM42,ARL2BP,EIF5B,PSMC5,CHCHD2,CLEC9A,CCL2,IGF2BP1,NPPC,KLHL25,SMARCE1,TENT4A,E2F4,LMNB1,HAX1,MIR1224,FOXP3,CD274,PPP1R12A,PPP2CB,ACTL6A,PADI2,CHMP1A,BAHD1,PTP4A3,ID4,ZBTB2,EIF4E,TP53INP1,ZNF581,MMP14,ZNF513,GNRH1,MAGEC2,MACIR,MIR648,ZNF507,MIR96,DNAJB6,SFN,NACC2,MIR383,MIR148A,ZNF24,ZBTB16,HDAC3,SMARCD3,IFNK,MIR454,PRKAG1,MIR887,TP53INP2,WNT10B,TXNIP,MIR577,RIGI,PAX6,SMYD3,GFPT1,SERTAD2,ITGA2,CCT7,RPL26,FUBP3,RPS4X,DUSP26,ACO1,TGFB3,SIAH2,WNT7A,VSTM2A,CEBPE,MIR374A,MIR877,ZNF688,MIR345,TEF,BAK1,VDR,SIRT7,TCF23,MIR331,PPP1R11,BRD9,CLK4,SAP30,NFKBIA,MIR492,AR,SOD1,IL2,MIRLET7B,CYTL1,MIR130A,CCND1,HIRA,TSC22D3,PAIP2,PID1,MED13L,XBP1,RPL13A,ATF1,DIO2,SMU1,MIR10B,RGMA,MIR450B,GNB3,MIR187,ACP5,FGF1,MIR125A,TAF11,PHC1,TCEAL1,CER1,ZNF790,JADE1,MIR147A,PAX9,HSPA8,CSRNP3,BAG2,INTS10,ZNF473,ZNHIT3,DDX5,NCBP2,MIR1-1,MIR583,TP53,MIR188,MDM2,HENMT1,SDCBP,RBM3,RBM15B,UFL1,HOMER3,FOXJ3,MIR218-2,MIR193B,TRIM52,CDKN1B,TRA2A,MIR1249,DROSHA,HEXB,MIR198,ZNF326,FAF1,PIWIL1,MIR195,ZNF526,TRIM15,ZBTB14,ZNF189,KPNA2,MIR335,ZNF692,MIR628,GTF2A2,PKIA,CCT8,MIR649,MIR98,KDM2A,CDK5,HEXIM2,MIR615,PLAC8,FGF7,ING1,PHB1,MIR624,FCGR2A,MUL1,NGRN,ANKRA2,MIR1298,CX3CL1,MIR552,PDCD1LG2,H1-5,IRF4,FUT8,CLDN3,CASC3,NLRP3,MIR214,H2AB1,MIR502,ZBED4,ZHX3,PPM1D,NLRP2,MIR301A,ZNF655,TMEM107,ILK,RPL6,EID2,MIR16-2,CDKN1A,MDFI,MIR105-1,TOP1,LSM14A,MED4,SUPT5H,TENT5C,KLF12,ZNF518B,MIR1225,STK3,SETD7,IRF3,MAP3K12,HEY2,RWDD3,EIF5A2,IL12A,MIR132,BCL10,HNF1B,MIF,NUPR1,SECISBP2L,AGO1,CRYAB,MIR302B,FLCN,ZNF652,MIR761,MIR484,MIR3173,AKAP12,DYRK2,RPS14,TLR3,TRIM68,DMTF1,CCL5,RORB,DGCR8,NKRF,MIR146A,SCML1,FAM98A,MIR662,MIR504,IL4,ILF2,MDC1,THAP1,RUVBL2,DKK3,ING2,LANCL2,MIR150,SPIN3,TADA1,MIR452,CPTP,MIR101-2,CHID1,GPBP1L1,SRSF7,LCORL,DDX4,ADRB2,HAND2,PRDM4,MBD3,CCR7,RNF8,STAT6,MIR367,GLRX2,HOXB1,MIR600,DKK1,RFC2,MIR9-1,SCAND1,LSM2,OTUD7B,RPRD1B,ZNF596,RERE,LRP3,MIR192,MAP2K3,PLD3,PARM1,RBM23,ZNF7,SNAI2,MIR489,NDFIP1,SART3,SOX9,CPEB1,CSNK2A1,HNRNPA0,GHRL,HOXC4,DHRS7B,PAEP,MIR558,NUCKS1,IRF8,CCR1,SAP30L,TRIM29,PRPF19,PELO,ING5,NR1I2,MIR339,CDC5L,EIF4EBP2,CD200R1,HNRNPK,ZNF22,ATF4,TRIM21,NOVA1,HEXIM1,ZNF609,ANGPT1,PPID,SRC,CDK20,MIR34C,NRDE2,SRGN,PTGES3,LGR4,MIR135B,MEF2A,PRKRA,IFNG,ZBTB5,BIRC5,TENT2,METTL14,ACTR2,TCEAL7,CTNNBIP1,CCT5,LMO3,MIR551A,NTRK2,IFI16,INSM2,UTP15,AFAP1L2,ITM2B,IRF1,PQBP1,MIR542,MOG,EXOSC3,CELF6,MIR29A,EDC3,TAL2,BMPR2,MECP2,MIRLET7I,MIR181C,TICAM1,SMAD9,STAP1,MIR653,ELP3,ZNF32,FCGR2B,ATF3,PCGF3,KLF10,MIR599,MIR924,SETD5,MIR205,SELENOK,TRIM62,IRF2BP1,TMIGD3,EIF4A3,KMT5B,TAF9,WNT2,HNRNPD,CCN3,CSRNP1,DUSP22,SMAD3,MIR24-1,SCML2,ELF5,RNF40,PLAGL1,TRIB1,MIR378A,HOXD12,CCL19,TICAM2,HP1BP3,MIR222,POU3F4,TRAF6,MIR802,MIR181D,MIR1180,NUDT12,HLF,MIR937,PLP1,SUPT3H,LRIF1,ZKSCAN1,NFKB1,ARG2,RPAP2,HNRNPF,CHI3L1,PSPC1,FOS,IRF2BPL,PRSS37,EMX2,CXXC1,FLOT1,ZFP1,MIR449A,MTA3,MIR885,CBX3,HSPD1,MORC2,JUN,PNP,ZFP64,MIR107,RSAD2,MIR1-2,USP2,RNF14,IL12B,UBE3A,PCBP4,POLR3B,MIR185,STOML2,MIR190A,FOXP1,RBFOX3,MIR519D,INHA,MTG2,MIR30B,MSX2,LILRA2,MIR375,TIA1,RGCC,MYBL2,ZNF280B,ILDR1,POGK,MIR548C,MIR651,ABCC2,MIR197,POU5F1,H3C1,RMND1,ZNF592,MIR33B,MIR593,POLR3F,MIR210,EIF4E3,SIN3A,ELK1,LYAR,TANK,SELENOS,MIR9-3,DRD3,H2AC6,MIR92B,PRMT5,MIR99A,MIR136,AKAP17A,GMNN,ZNF862,LMNA,ZMYND11,GPX1,ANXA7,TMEM106A,LSM14B,BACH1,OVOL1,WDR77,PIK3R3,RFC3,EP300,CRKL,MSN,TRIM24,CDK12,CTDSP1,PHF21A,H2AC4,MIR643,MIR206,MLLT11,SNX12,ODAM,AATF,DEDD,GSK3A,KPNA6,RAMP3,TIRAP,PKIB,BST2,MIR573,MAF1,TRIM27,FOXI3,CDK6,NONO,TFPT,HDAC11,PTPN11,HUWE1,ENC1,CKS1B,VGLL2,SCAMP5,MIR155HG,ACSS2,PIWIL4,HELT,ATXN1L,FGFR1,ZNF671,IL13,MIR609,MIR34A,CLEC7A,IL21,MIR216A,VPS72,MITF,ZNF451,TENT5D,IDO1,TAF7,SFRP4,RPL23,PTGER4,MIR626,CCNA2,SP1,MIDEAS,RNF187,GPNMB,JUP,MIR711,DCP2,BTG2,TSPO,ZBTB6,RNF20,IER2,RFXAP,EZH1,MIR1262,ITK,IL7,ESR2,FZD6,CNOT7,TGFB1I1,MYRF,GAPDH,MIR934,SLC6A4,RAD21,POLR2L,LSM6,BATF,ZNF304,MIR361,MIR23A,AGER,S100A10,LARP4B,EPHA2,ZNF770,INO80C,CXXC5,YTHDF1,MIR495,EEF2,RPS3,TRIM6,FOXP4,ETF1,TRAF2,CBX5,NMBR,YAF2,MIR567,H2AZ1,ROCK2,FGF17,LBH,ADIPOQ,ACOT8,MIR1277,RHOH,MIR581,MIR657,MIRLET7C,CGGBP1,LDB1,XAF1,MTRES1,DIS3L,TFDP2,OGG1,MIR424,FBXW11,RAG1,SPINDOC,H2AX,JPH4,SPHK2,TNFRSF14,CXCL10,PSMD10,MAGED2,KDM4B,H2AC13,CDK5R1,HSP90AA1,TGIF2,SMAD5,KLF9,SAP30BP,APLN,MOV10,GATAD1,HTR2A,INPP5K,PSRC1,CD83,MIR190B,SASH3,APOBEC3G,PRDX3,TDRD7,MIR556,FRMD8,CREB1,WWP2,HNRNPA1,MIR216B,GLO1,THOC2,SPON1,G3BP1,LILRB4,ARB2A,RPS27L,EGR2,HBEGF,AP2A1,TRIM26,ZBTB42,ZGLP1,TAF2,WWP1,GFI1,ZMYM2,ZMPSTE24,RUNX1,MIR208A,IFIH1,PKIG,ZCCHC17,MSTN,MEF2C,BEND5,CD28,TAX1BP1,HSP90AB1,CBFB,VGLL4,RC3H2,SMG5,TRIM11,SP4,GREM1,MIR940,MTDH,ADTRP,CDH13,PIWIL2,CCNQ,HSBP1,PXYLP1,ABHD14B,NFKBIB,PDE8A,SOX2,PTPN22,IRF2,USP13,TRIM37,MXD1,ZBTB38,RING1,PCNA,MIR612,MIR144,PAK6,METAP1,CRYBA1,CHP1,TGFB2,HNRNPH2,ACTA2,RASL11A,CRIP1,NOTCH2,SRPK2,SVIP,RBM7,CDK7,MAFG,ATP1B1,BAZ1B,NFE2,TADA3,CIRBP,HBP1,CCL21,MIR20A,TRAF3IP3,ZNF250,SHC1,CTBP1,PRKCB,ZNF174,PAGR1,ZC3H14,RIT2,MACROH2A1,MIR708,ATP2B4 |
| 2.753e-07 | -15.11 | HIV Infection | REACTOME pathways | R-HSA-162906 | 236 | 111 | 10285 | 3229 |
ARF1,AP2A1,PSMB3,CD247,CHMP5,SLC25A4,PSMA5,CCNH,MNAT1,POLR2B,TAF2,PPIA,PSMD10,KPNA1,UBA52,TCEA1,TAF7,TAF10,GTF2A2,GTF2F2,POLR2G,SUPT4H1,GTF2B,CCR5,TAF11,SSRP1,PSMC1,ERCC3,CDK9,FURIN,NUP42,PSMB2,PSMD1,PSMA6,HMGA1,VTA1,GTF2H4,VPS4A,TSG101,POLR2C,NUP62,SEM1,NCBP2,VPS4B,PAK2,PSMB4,GTF2H5,RPS27A,PSMD4,AP1S2,PSMC3,TAF9,PSMA1,PSMA3,PSMB5,PSMC4,CXCR4,PSMD3,APOBEC3G,PSMB7,PSMB1,NUP50,PSMB6,PSMA2,CD28,BANF1,GTF2A1,PSMA4,PSMC5,PSMB11,PSMB10,B2M,PSMD7,GTF2E2,CDK7,SKP1,ELMO1,PSME1,POLR2D,POLR2L,GTF2H2,UBB,RANBP1,AP1M1,PSMD14,POLR2F,ELOC,SLC25A5,PSMD12,NUP37,XRCC5,RAN,CD4,VPS28,AP2M1,POLR2I,GTF2F1,XPO1,NUP107,FEN1,AP2S1,PSMB9,NUP153,CHMP2B,CHMP4C,SUPT5H,PSME2,GTF2E1,PSMD6,NUP35,CHMP2A |
| 2.757e-07 | -15.10 | GTPBP10 (GTP binding protein 10) | protein interactions | 85865 | 133 | 65 | 19454 | 5460 |
MALSU1,SURF6,CAND1,FZR1,MRPL50,PCBP4,GATD3,FAHD1,SSBP1,FBXO32,MRPS26,RPL10A,SMAD4,MRPL18,RHOG,SNRNP70,CHCHD1,DDRGK1,IFI16,GRSF1,MTRF1,PFDN5,PLEKHO1,RPL28,IMMP2L,RPL3,CLPB,DHX9,COX8A,FGF3,GFM2,DCUN1D5,EXOC3,PDHA1,METTL15,RAF1,MRPL11,MAGEB10,RPL10,RPL7L1,RPL13A,PRKRA,MRPL13,TACO1,IRF2,PNMA1,MTG1,UBE2H,MECP2,ZNF668,TUFM,MYC,AUH,MTG2,RPL7A,PMPCA,UFL1,RPL4,GFM1,AMACR,EXD2,RPL26L1,RPLP0,MTRES1,APOBEC3C |
| 2.757e-07 | -15.10 | DUT (deoxyuridine triphosphatase) | protein interactions | 1854 | 133 | 65 | 19454 | 5460 |
LGALS3,UMPS,COPE,PRDX2,TAGLN2,PPP5C,ENO2,ENO1,NUDT18,MSN,PTEN,POLR3B,RHOB,RIT1,UBE2H,CUL3,MYC,CFL1,GRPEL1,MAVS,GPX4,HSPA8,METTL14,CTBP1,CDK1,CKS2,PIH1D1,LEMD3,HEXIM1,SPR,CDC42,RND2,PRNP,RAB1B,PLEKHF2,G6PD,RAB11B,NUDT9,TYMS,AK2,GSTO1,COTL1,PPP1R11,HSPB1,GAPDH,SPATA2,HNRNPA1,KRAS,RIGI,IMPA2,COPS4,HSPD1,RAB1A,TAGLN3,HINT1,ABCE1,SOS2,TGIF2,GDI2,NGB,EZH2,UBL4A,TPD52,PPARA,EEF1A1 |
| 2.758e-07 | -15.10 | WDR76 (WD repeat domain 76) | protein interactions | 79968 | 374 | 150 | 19454 | 5460 |
ATP5F1B,TUBB,RBBP4,ACTB,POLR2B,CBX5,GNB1,PARP2,CKB,CCT2,LMNB1,YWHAZ,HSP90AA1,BAX,POLR1B,HNRNPAB,CUL3,HNRNPC,SMARCE1,PRPF31,MCM4,CPSF2,PCCB,SLC31A1,HNRNPA0,TRIM52,FTL,XRCC5,HSPA8,HADHA,APOBEC3C,ACAA2,SLC25A3,ACTL6A,PGRMC1,TIMM13,PRDX3,NOP58,GFOD1,SPTAN1,TCP1,DYNC1I2,CETN2,CCT7,CCDC71,DNM2,MRTO4,SRSF1,KRT8,H2BC17,HNRNPD,DDX1,YWHAB,DPY30,WWP2,PPIB,XPO1,DDRGK1,RBBP7,KRAS,LAMB2,GTF3C3,POLDIP3,SSRP1,HNRNPDL,PCGF6,HSPD1,SLC25A5,CCT8,HNRNPA2B1,PCNA,BAG2,RTCB,EZH2,TUBB4B,RPS23,MAX,RAF1,FEN1,SUPT5H,TUBA1A,PPP2R1A,TNPO2,PPP1R10,RPL22,PSPC1,TNFRSF1B,CTNNA1,TUBA1B,LIG3,EIF4A3,RTRAF,SEC61A1,CSNK2B,MACROH2A1,DNAJC10,ATP1A1,SMARCA5,RUNX1,RPS17,ATP5F1A,TUFM,NONO,GTF2I,KDM1A,RPL4,HMGB1,SMC4,HSPA5,RPA3,HELLS,EGFL7,H2BC12,LMNA,RPA2,H2BC11,RPRD1B,HSP90B1,PICALM,MACROH2A2,SPTBN1,MYL12B,GTF3C4,TOP1,AIFM1,SSBP1,SYNCRIP,HRAS,H2AZ1,SMCHD1,H2AC4,EXOC2,BRD3,H3C1,CSE1L,H2AC6,MSH6,EIF3E,MAP1B,PSME1,DHX9,HSD17B10,EXOC3,CHAMP1,CBX3,CAPZA2,RAD23B,RPSA,CCT5,EMILIN3 |
| 2.765e-07 | -15.10 | cytokine receptor binding | molecular function | GO:0005126 | 273 | 121 | 18094 | 5411 |
CCL5,CCL17,TGFBR2,FKBP1A,IL7,IL15,IL3,IL22,IL17F,JAK1,IFNA10,CCL11,SIVA1,TGFB3,PIK3R1,VEGFC,GREM1,IL13,CCL2,XCL1,TNFSF18,IL12A,TRAF6,TNFSF10,DEFB114,IL21,LTB,TOLLIP,CXCL9,CXCL10,PYCARD,IL34,IL10,IL2,CXCL12,CCL19,CX3CR1,NTF4,IL4,CCL23,CNIH4,IFNK,FEM1B,SYK,CSF2,IL1B,TRIM37,CCL8,STAT1,CCL27,CSH1,CX3CL1,IL23A,CCL20,CXCL3,CCL3,IFNG,BEX3,GH1,SHC1,TNFSF13,CCL24,TNF,CCL28,CXCL11,CCL1,IFNB1,SMAD3,SPRED1,TNFSF8,TNFSF15,CXCL13,FASLG,CXCL14,CCL21,CD40LG,IFNA2,IL5,STAP1,IL1A,SMURF1,TRAF1,IL18,IL1RAP,CCR2,IFNA13,JAK2,DDT,CCL18,MYD88,TNFSF12,LTA,CXCL8,IL12B,CXCL1,DEFB1,MIF,TMBIM1,SPRED2,EFNA5,IL6,TLR5,CCL25,RNF41,OSM,IL6ST,SMAD2,USP15,CKLF,EPO,CCL4L1,SDCBP,TRAF2,TGFB2,MSMP,PRL,VEGFA,TLR9,SOCS2,FERMT2,IRAK4 |
| 2.780e-07 | -15.10 | GEMIN4 (gem nuclear organelle associated protein 4) | protein interactions | 50628 | 266 | 113 | 19454 | 5460 |
DMPK,KRAS,EWSR1,POLR2C,RHOBTB1,SNRPE,NFKBIL1,CHMP4C,HDAC11,SPG21,RAF1,B3GNT2,EGLN3,SNRPD3,HAX1,DICER1,HSPB1,RPL23,P2RY10,DDRGK1,HR,PXMP2,UFL1,TRA2B,NPTN,DUSP26,CD40,SNRPA,CRYAB,MED23,TIMM29,MTX2,MORC4,MAD2L2,ESR2,SNRPB2,ERH,LGALS3,SNRPD2,SNRPD1,PHF21A,LMBR1L,S1PR4,BAD,ILK,MYO6,SNRPB,MYC,CUL3,OPRM1,GPR17,SMN1,SNRPG,CTNNBL1,DHX9,GEMIN7,PPP4C,TAF2,SPRY1,SIGLECL1,MGARP,CD2BP2,UBL4A,COMTD1,KBTBD4,MTCH2,CDK4,ILVBL,CDC5L,TOP1,PSMB1,COX20,FA2H,SYNCRIP,EEF1AKMT3,USP15,MUL1,SLC2A1,CHCHD1,SNRNP70,RPL24,GTF2E1,COPS5,KARS1,USP2,KDM1A,SQSTM1,RPA3,BAP1,SIRT7,TTI2,RPA2,CDK1,P2RY12,ZNF326,LSM2,METTL14,FAXC,HCST,AGO1,GTF2H4,SNRPN,VIRMA,SRP54,PTEN,CCNF,TYROBP,UBE2H,MRPS16,GEMIN8,TIA1,PHKA1,CIAO1 |
| 2.784e-07 | -15.09 | intracellular signaling cassette | biological process | GO:0141124 | 837 | 313 | 18204 | 5365 |
PPP3CA,CXCR6,PDE8A,KBTBD2,CEBPE,RAP2B,NDNF,IL1B,BTBD10,SIAH2,AKT1,GSTM2,DELE1,TNFSF15,CDH13,CCR7,TLR6,MAPK4,CCR6,NYAP2,SMAD4,FKRP,GRB10,TANK,CREBBP,PDE1A,IGF1,KRAS,NFKBIA,EP300,TAX1BP3,KARS1,CHP1,MAP2K3,PIK3R3,NPR2,FGF10,CTNNB1,DEFB1,RIT1,OXTR,TRIM8,RALA,TF,NFE2,CREBZF,CDC42EP2,RHEB,SOX9,CCR5,TGFBR2,ATP1B1,BECN1,LAT2,CRKL,DLG1,SLC8A1,ATP1A2,RND2,AR,TLR7,PTEN,PPP5C,GRAP,PPP3R2,ATP2B4,NCKAP1,SMAD1,RASGRP2,RIT2,IRAK1BP1,NCALD,PRKCE,ADCY2,MAP2K1,CCR1,PPP1CC,MAP1LC3A,MAP3K14,IGFBP4,ATF1,DIRAS3,RAP1B,JUN,RAB18,CCL3,JUNB,RAB9A,ROPN1B,ERRFI1,CDK1,BCL10,HTR2A,SCG2,MAP3K12,GRAP2,SMAD5,BTN2A2,SPRY1,PDE7A,STK3,CFL1,GDI2,RGS19,G3BP1,G3BP2,PEA15,DOK6,SOS2,TLR3,BRAP,DEFB124,PDE6A,RAB4A,IGF1R,CREB1,FLCN,MYC,CRYAB,DUSP19,RTKN,CDC42,PLA2G4B,ZMPSTE24,TLR9,HACD3,SMAD2,MYD88,IGFBP3,MTM1,MIR146A,CD4,TNIK,PRDX4,MCOLN1,CLIC2,CAV1,PPP1CB,DOK4,USP8,VAV2,TAB1,CDC42EP4,CD28,CD36,FKBP1B,CAV3,RERG,MEF2C,DDAH1,STUB1,GNB1,CCR4,SYK,CXCR1,ELMO1,CD40,RHOU,BCL6,RALB,EPHA2,CXCR4,PRR5L,RASL10A,NKX3-1,NFKBIL1,RGL2,BATF,RHOB,DUSP10,ERAS,MAPK10,CREB3,HRAS,TNF,CCR3,MAP3K11,ROCK2,SMAD3,RAF1,CCM2,CX3CR1,TRAF2,RAP1A,RHBDD3,COL1A2,RAB33B,BIRC2,RHOBTB1,RASD1,LACRT,RAB33A,RAB9B,RGL1,PLN,DUSP9,DMPK,CD2AP,CXCR3,CEBPG,TLR2,TRAF6,P2RY11,AIF1,CCR2,TIFA,RAB35,RASGEF1C,MAPKAPK3,RHOH,CDC42EP3,TRIB1,TBK1,DUSP6,FOS,CHI3L1,NPPC,INPPL1,MAP2K6,PDE2A,CDKN1A,MAPKAPK5,PML,RPAP2,NFKB1,CHRM3,KCNJ8,GUCY1B1,NKIRAS2,ILK,EIF2S1,CITED1,ADNP,RB1,FGF13,STRADB,MRAS,CGAS,TBC1D10C,OPRL1,RAC2,TMEM38B,ACKR3,ITGAV,FGFR1,RAB30,PRDX1,KCNJ11,ARHGAP1,RAP2C,NKIRAS1,ADRA1A,CCL11,TLR4,DDIT3,PDE4B,EPS8,KRIT1,ATF4,PIK3CG,CXCL8,TIAM1,PIK3CA,NUDT4,PAFAH1B1,SDCBP,ARHGAP5,RRAS2,DOK5,TAB2,TP53,MAP3K21,MAP3K3,SYNJ2BP,MIR1-1,MEF2A,ROCK1,HPCA,P2RY12,PDE9A,RABIF,RAPGEF5,PIK3R2,IMPACT,SBK2,RAP2A,PIK3R1,RND3,RHOJ,IRAK4,GSTO1,RHOG,YWHAZ,LIPA,RACGAP1,TLR8,CAP2,RAB39B,RASGRP3,CCNA2,RFXANK,GARRE1,SHOC2,PTGER4,NFE2L2,SMAD9,PDE1B,RCE1,ARHGEF6,IKBKB,FGF23,ADGRG1,NF2 |
| 2.785e-07 | -15.09 | VANGL1 (VANGL planar cell polarity protein 1) | protein interactions | 81839 | 229 | 100 | 19454 | 5460 |
STX7,PXMP2,SAP18,NT5C3A,RNF41,HADHA,EMP3,RAB5A,SDC2,THAP2,BET1,SEC62,RND2,OTULINL,MANSC1,APEX1,ESR2,RMDN3,SEC61B,LAMTOR1,FBXW11,MYO6,RHOB,NTRK3,RAB11A,EPHA4,KRAS,FLOT1,ARGLU1,CD83,TMT1A,COX8A,RPS24,RPN1,STIM1,NFKBIL1,RAB4A,RND3,ZRANB2,MOB3C,OTULIN,DNAJC25,RHOH,DIRAS3,RAB35,SDC4,GJA1,RHOG,LAMP2,SYNJ2BP,ZCCHC10,INO80E,RAB5C,RHOU,DVL2,DERL1,RAB9A,FGFR1,SSR1,ATG16L1,CDC42,FBXL19,ST7,SMYD3,RAPGEF5,RHOJ,RPL22,SEC63,VIRMA,TNFRSF1B,FGFBP1,CYBC1,LGALS8,TYROBP,EPHA2,RAB2A,DNAJC5,CAMKV,RAB3B,ARF4,FKBP8,NTRK2,RP9,JPH4,ARF6,DNAJC1,TMPO,STX6,LMAN1,CAV1,HRAS,PTPN1,HSD17B11,RAC2,ESYT1,STYK1,BRD3,DPP4,SLC25A46,LAMP3 |
| 2.799e-07 | -15.09 | PURB (purine rich element binding protein B) | protein interactions | 5814 | 141 | 68 | 19454 | 5460 |
MYC,RPL7A,CUL3,RPL26,PSMD1,RC3H2,MIR363,UBE2H,FAU,RPS3,PRKRA,PRMT5,PTEN,RPL35,ESR2,SRPK2,MAD2L2,RBFOX2,MIR34B,SYK,FGF13,CFTR,RPA2,HEXIM1,RPLP0,MACROH2A2,MIR7-1,RPA3,MIRLET7I,PRKCB,MTDH,EP300,RPL4,MIR7-3,UTP23,GRSF1,CSNK2A1,MIR29C,CPEB1,RPL24,H2AC4,SNRNP70,MIR31,RPS2,POU5F1,SRP14,KRR1,NABP1,MIR25,RPS10,PRNP,CGAS,MIRLET7G,CD1A,RAF1,ARFGEF1,RPSA,CCR1,RPL31,MIR9-2,RPL23A,RPL3,CNOT7,H1-6,G3BP1,AP1M1,MEPCE,RFC3 |
| 2.799e-07 | -15.09 | MAPK7 (mitogen-activated protein kinase 7) | protein interactions | 5598 | 141 | 68 | 19454 | 5460 |
HSP90AB1,EGLN3,SPPL3,GJA1,CORO1C,GYS1,HSPB1,YWHAB,PPP3CA,CD9,GAPDH,YWHAH,XPO1,YWHAG,PFDN5,PRPS1,H2BC14,PFDN1,RUVBL1,TMEM33,BAG2,GPSM3,PRPSAP1,RUVBL2,MEF2C,SLC25A5,NFE2L2,TUBB4B,ACTN4,TP53,PTS,RAF1,TRMT1L,APEX1,NR1I2,TUBB,SPINDOC,ACTB,SLC25A4,GANAB,GTF2A1,TUBA1B,ENO2,PFDN6,HSP90AA1,PFDN2,PFDN4,ATP1A1,IVNS1ABP,YWHAZ,BAG3,ATP5F1A,H2BC9,MYC,HSPA5,MEF2A,H2BC12,HSPA8,ZKSCAN1,FOS,PML,SNRPA,MACIR,SLC25A3,PRKCA,HSP90B1,JUP,ELK4 |
| 2.815e-07 | -15.08 | CD81 (CD81 molecule) | protein interactions | 975 | 292 | 122 | 19454 | 5460 |
GNAI3,TFRC,LBR,EEF1A1,TP53,SERPINB9,RPL17,H2BC14,CTSC,EIF3E,RPS13,TF,HNRNPK,MRPS18B,GNG5,RPL23A,ADRA1A,RPS2,CD9,SHC1,RPL24,GAPDH,GNG2,CD81,TMPO,RPS16,CD151,ALCAM,CD4,RAC2,ALYREF,RPL12,ITGA6,SYNCRIP,RPLP0,GPR35,LMNA,H2BC11,CD46,GNG7,RPS14,RPL4,RPS15,H2BC12,TMX2,RPL27,PDCD4,ATP1A1,EIF3G,TUFM,NONO,H2BC9,ATP5F1A,CFL2,CFL1,AKT1,GNAI2,RPL22,CCR2,F11R,RAB14,MSN,CSNK2B,TUBA1B,CHRM4,VAMP3,RPS3,RPS23,H2BC1,TUBB4B,H1-3,ACTN4,TUBA1A,ANP32B,RPS4X,KIT,LASP1,ZBTB16,PDIA6,SRSF8,EWSR1,HNRNPA2B1,PABPC1,RPL31,GNA11,STX1A,CBL,HNRNPD,PDZK1IP1,H2BC17,HNRNPA1,RPL6,INPP4A,CRIP1,DHX15,SNRPD3,RPLP2,CD63,ATP5PO,TSHR,RPL27A,ADRB2,SDHAF4,DDX5,RPS28,OXTR,H1-1,RHOB,SNRPB,MRPL16,SAMHD1,GNB1,RPL35,RBBP4,TUBB,ACTB,EIF4A2,RPS9,BST2,SNRPD1,EIF3K,FAU |
| 2.823e-07 | -15.08 | FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3) | protein interactions | 117246 | 386 | 154 | 19454 | 5460 |
ZNF574,RPL26L1,RPLP0,HEXIM1,RPA2,CDK7,ATG16L1,PSMC4,BRIX1,UTP23,WDR55,RPL4,EIF5B,NPM3,DGCR8,RAB9A,MTDH,RNF113A,SIRT7,BAP1,RPA3,UBE2H,PPP1CC,DNAJC8,RPL7A,RPF2,DEK,RPL22,VIRMA,SRPK2,SMURF1,RPL13A,ZNF622,NDN,PRKRA,CSNK2B,FGFBP1,ZNF330,EIF2AK2,PSPC1,SF3B6,CCNF,SRP72,ILF2,HBP1,RBM34,LLPH,CDK8,RPL15,AURKAIP1,RPSA,TP53,RPL17,MEPCE,H3C1,RPL23A,RPL3,SNIP1,RPL10A,BRD3,NOL12,SNRNP70,H2AC4,MPHOSPH10,CHCHD1,TUBG1,COPS5,CSNK2A1,HDAC6,PLEKHO1,GRSF1,SURF6,CDC5L,KLF9,CDK9,DKC1,CGAS,CAND1,RPS16,KRR1,RCHY1,SRP14,AGGF1,PALS2,APOBEC3C,BET1,RPL27A,H1-5,SYK,NOP53,STAU1,UFL1,SAT1,NSA2,H1-1,DNAJB6,RIT1,MYO6,ZNF668,RPL39,GRB10,RAB11A,CUL3,MYC,APEX1,RPL10,RPL19,SNRNP40,RPL35,RPS9,RPL37A,SURF2,RPL18,SART3,PPID,CHMP4C,EZH2,LGR4,ISG15,NCSTN,SOX2,MAK16,H1-3,SUPT5H,E2F4,RAF1,FANCG,RPL28,MRPS17,UBE2A,HMGN4,G3BP1,KRAS,RPS24,PPAN,RPL31,DRG1,LHX2,WDR12,DDX23,DDRGK1,RPL6,WWP2,IFI16,LYAR,NOB1,NOP58,PAIP1,HP1BP3,EED,SRSF1,MRTO4,RPL9,RPL8 |
| 2.835e-07 | -15.08 | POLR2H (RNA polymerase II, I and III subunit H) | protein interactions | 5437 | 215 | 95 | 19454 | 5460 |
WWP2,DDRGK1,CTNNB1,IKBKB,RASSF8,MED4,POLR2L,PHB1,RPRD1A,POLR3F,EGLN3,SUPT5H,MED9,MAX,TRMT1L,GTF2E2,SART3,POLR2D,POLR2C,RUVBL2,RPAP3,RUVBL1,KRAS,CUL3,MYC,NFYA,LMO2,BAG3,FBXW11,BRCA1,MED10,PFDN6,MAF1,POLR1B,RIT1,PFDN2,NFKBIB,GTF2F2,GTF2F1,POLR2F,POLR3B,INTS10,MED17,ESR2,POLR2B,PIH1D1,MED31,XRCC5,CD40,MED13L,MED11,SKP1,ERCC3,NFKB1,POLR3GL,CSNK2A1,GTF2E1,MED29,MED21,NME2,MED27,BRD3,GTF2B,POLR2I,TOP1,ASNSD1,PSMB9,RPAP2,CDK8,NUPR1,POLR2G,METTL18,HSD17B10,KPNA2,DNAAF10,SOCS2,PDRG1,MED22,AR,SPOP,UBE2H,CCNF,POLR3H,PTEN,SRC,TPT1,NFYB,UBE2W,POLR1D,MED30,RPRD1B,JUP,ELOF1,FBXW7,POLR1H |
| 2.877e-07 | -15.06 | SLC10A1 (solute carrier family 10 member 1) | protein interactions | 6554 | 120 | 60 | 19454 | 5460 |
VKORC1L1,TVP23B,VAMP3,CDIPT,CYB5R3,SLC38A1,SLC35E4,FAXDC2,SMPD2,FCER1G,ARL6IP6,STX7,RABAC1,DERL1,ORMDL1,LRP10,FDFT1,VAPB,IFTAP,SEC22A,TMUB2,CFTR,GOSR2,TMEM97,TSPO2,CXCL9,SLC66A2,COX20,FA2H,BTN2A2,FAM241B,FXYD6,EMC6,SLC41A1,ORMDL3,PMP22,SLC38A7,SLC25A46,SFT2D2,FKBP8,TOMM6,SACM1L,TMEM60,UNC50,ATP6V0B,YIF1A,TMEM147,RUSF1,SFXN1,STX12,CYB5B,TFRC,TMBIM1,YIPF4,UBIAD1,GDE1,MFSD6,INSIG2,SELENOK,NEU1 |
| 2.886e-07 | -15.06 | positive regulation of lymphocyte proliferation | biological process | GO:0050671 | 143 | 71 | 18204 | 5365 |
CD38,TLR9,TACR1,PRKCQ,TRAF6,MYD88,IL4,CD46,CCL19,AIF1,EFNB1,CCR2,IL2,TGFBR2,MIR30B,MIR21,PDCD1LG2,CD81,IL5,IL2RA,TICAM1,JAK2,EPO,IL15,CDKN1A,TIRAP,IL23A,CD80,CD28,IL7,MEF2C,CHRNB2,CD1D,HMGB1,SASH3,PNP,IL18,MIF,PPP3CA,BCL6,FOXP3,IL12A,CD274,DHPS,IL1B,CD40,IL6ST,PELI1,AGER,PYCARD,TLR4,CD40LG,LEP,IGF1,CD209,CCL5,IL1A,SLC39A10,XCL1,SLC7A1,IL12B,FGF10,GPAM,IL6,IL21,CD86,TFRC,IL13,NCK1,RPS3,SELENOK |
| 2.900e-07 | -15.05 | positive regulation of catabolic process | biological process | GO:0009896 | 622 | 241 | 18204 | 5365 |
MIR24-1,ROCK2,DDRGK1,TNF,ATG16L1,VSIR,PDE12,CNOT6L,PSMC4,LACRT,TRIM6,HNRNPD,TRIM32,RHBDD3,SLC25A4,TNRC6C,MIR145,MIR191,RALB,VPS28,ORMDL3,MIR495,PSMC1,CLU,HMGB1,YTHDF1,STUB1,STK11,MIR23A,TRIM5,PLEKHF1,FBXW7,MIR98,PRR5L,ABHD5,OAZ2,GTPBP1,SH3GLB1,PSMD10,SUPT5H,PSMC5,DISC1,MIR424,PABPC1,TRIM23,SLC25A5,RNF152,MIR16-1,MIR491,MYLIP,FXR2,MIR373,MIR181D,MIR214,TRIB1,TBK1,HSPB8,VIP,TMEM59,PIP4K2C,MIRLET7C,PIAS1,GNAI3,IFNG,MIR34B,CCNY,MDM2,DTL,STX5,MIR135B,ATG101,OAZ1,TOM1,ROCK1,OAZ3,MIR1-1,PTPN1,BAG2,ADORA1,SH3BP4,ASB11,SUMO2,MIR340,TNFSF12,CNOT8,RB1CC1,MIR26B,MIR140,TRIM21,TFEB,RNF41,POLR2G,SQSTM1,MIR181C,TGFB1I1,APOC2,CNOT7,DET1,RNF139,FBXO7,NFE2L2,TICAM1,MIR137,BNIP3L,EXOSC3,YTHDF2,MIR195,FAF1,FBXO22,SESN2,MIR106A,MIR625,HECTD1,BTG2,MIR100,COP1,CDKN1B,MIR193A,DCP2,CSNK1A1,CCDC22,SGTA,METTL14,UFL1,MIR212,GRSF1,ZFAND2A,SNX18,PACSIN3,MIR192,IGF1,SVIP,CNOT2,MIR9-1,TRIM8,TNFAIP3,SESN3,SEC22B,AKT1,NOP53,IL1B,GCLC,USP13,MTDH,C9orf72,ADRB2,MIR211,GABARAP,RNF128,SNX33,EXOSC8,MIR125A,PCSK9,MIR708,MIR200C,PTEN,RGMA,BAD,SUMO1,CDK5RAP3,PRKCE,EGLN2,GSK3A,BAG3,MIR206,SOX9,NDFIP1,TRIM22,MIR20A,MIR320A,CSNK2A1,MIR497,MSN,CNOT6,BECN1,MIR130A,PSMC3,MIRLET7B,MIR185,TRIM68,MIR106B,MIR223,FZR1,DAPK1,CDC20,NUPR1,AGO1,MIR142,RCHY1,TP53INP1,BAX,ZER1,CSNK1E,IER3,IL6,FLCN,LDLR,HTR2A,VDAC1,MOV10,MIR885,AKT2,TRIM34,MIR190B,PPARA,WDR45,TRAF7,SOCS4,MIR130B,PAFAH1B2,HSP90AA1,MIR204,MIR423,FURIN,RC3H2,CAV1,IFNB1,CAV3,DXO,USP5,PIM2,VGLL4,OPTN,MIR210,MIR342,IL4,ALKBH5,ATG7,TLR9,TNFRSF1B,SOCS5,SMURF1,DNAJB2,MIR96,MIR30B,MIR519D,PSEN1,MIR146A,CD81,MIR149,IDE |
| 2.913e-07 | -15.05 | PDIA4 (protein disulfide isomerase family A member 4) | protein interactions | 9601 | 431 | 169 | 19454 | 5460 |
H1-5,TOR1AIP2,PAFAH1B1,PRDX3,SEC62,CNPY3,EDEM3,KLF3,ISOC1,FKBP10,PEBP1,DNAJC3,DDX39B,TMEM106B,P4HA2,VLDLR,HSPA8,ATP5IF1,MIA2,EP300,AKAP1,STK26,EMC1,PRCP,STAU1,PAFAH1B2,PXMP2,GGH,SPCS3,BRCA1,NTRK3,ZMPSTE24,SERPINH1,LMBR1L,PIGK,RMDN3,SEC61B,PSMD4,B4GALT3,TUBB,GADD45G,ATP6AP2,NAA15,B3GNT2,ANP32A,RAF1,DHX38,E2F4,CCDC134,DNAJC25,ERLIN2,RPS7,CBLN4,RPN1,EZH2,STIM1,IRF8,CHMP4C,NGB,PTRH2,PLD3,NCR3,EWSR1,SEC11A,PDIA6,ERP29,FKBP2,AHCYL1,IMMP2L,ANP32B,SAR1B,PDIA3,IFI16,YWHAG,PPIB,YWHAH,EIF3D,AGR2,PEX3,YWHAB,BCL2L1,PHB1,PCSK9,DNAJB9,DYNC1I2,SUMO2,ERLIN1,COX14,OS9,CDK7,CFTR,RPRD1B,P3H1,RPA2,FGFR1,WWP1,HSP90B1,UBE2M,MET,HEXIM1,BAP1,APMAP,RPA3,SOD1,ARHGEF6,SIRT7,PGK1,CST11,PPP1R2,WDR55,HSPA5,ARHGAP21,SLC35B4,TUFM,SDF2L1,STK24,DNAJC10,LGALS8,NRP1,CALU,UBE2H,GXYLT1,CCNF,TUBA1B,GANAB,DNASE1L1,TRIM24,MSN,RAPGEF5,CTSB,MGST3,SEC63,CCDC47,TP53,H2AX,APOO,GPX7,TFRC,HSPA13,SELENOF,PPME1,CAPN2,NAE1,PCYOX1L,ERO1A,IGF1R,DNAJC30,HSPE1,VWF,RIGI,PRDX4,CALR,DPP4,EDEM1,PGAM1,HDAC6,TPM3,AKAP8L,ZNF652,UBE2N,COX4I1,OR4N5,CHID1,LDLR,MIF,THOC1,LMAN1,EPHB6,PLGRKT |
| 2.923e-07 | -15.05 | TRRAP (transformation/transcription domain associated protein) | protein interactions | 8295 | 754 | 274 | 19454 | 5460 |
TXN,TMOD3,ZNF622,SLC25A4,TECR,SEC63,VIRMA,GNAI2,ASTN1,TRIM27,ALB,ODR4,TADA3,IVNS1ABP,PIM2,TADA1,TAF5L,EMILIN1,CTSD,AR,PPP1CC,GMPS,SGF29,USP8,MBD3,LSM8,RPA3,PPM1G,SIRT7,TRNP1,PPIH,ARPC2,MTDH,HSP90B1,H2AC7,TTI2,TMOD1,SH3GLB2,EPHX1,PLAC1,RABL3,CPSF4,BRINP1,ELP3,KLF12,DCUN1D1,CDK9,TOMM70,ASNSD1,H2AZ1,LDLR,PRICKLE2,MPHOSPH10,DNAJC7,EI24,HDAC6,CTNNBL1,EIF3E,MDC1,TCOF1,RGS6,DMAP1,ILF2,AKR1C1,ING1,DDX39A,SOX9,LGALS3,MED17,MAD2L2,VPS72,SNRPD2,FAS,PSKH1,HNF1B,CFAP20,PYCR1,CUL3,TXNRD2,SCN3B,RFC5,SMARCE1,MCM4,CCDC186,SKP1,UNC45A,G3BP2,ADGB,EMG1,MED23,VAV2,H2AC1,MYL6,NDE1,WDR77,ACTL6A,H1-5,SUPT3H,PRDX3,CDKN1A,TIMM29,RAB6A,INA,LRRC24,SPTAN1,TRIM15,CACYBP,CNTROB,PPIA,DHX15,PSMB5,MRTO4,FAM3A,XPO5,BRD9,DDX23,SKIC8,HNRNPD,PDIA3,DYRK1B,TAF7,PSMD3,FIG4,EMC6,TMED7,COPS4,SSRP1,HSPD1,PCNA,SLC39A7,SRSF7,BPIFB1,EZH2,GDI2,DHRS3,KBTBD3,EIF1AX,SF3B5,HSDL2,E2F4,WDR37,IRF2BP1,BUB3,CDC20,NR1I2,RSL24D1,RASL11A,PSPC1,LIG3,PSMA6,NIF3L1,CISD1,CSGALNACT1,VPS39,MORF4L1,ARHGAP21,H2BC9,KDM1A,STK38,SEPTIN6,TMEM263,HPS6,RPA2,CLIP3,SUPT7L,CYC1,SPTBN1,ING5,MPV17,CDC42,SHPRH,ILVBL,SURF6,TEF,SSBP1,STT3A,HCLS1,RAC2,CENPL,SMCHD1,KPNA1,LSM3,TAF9,ENY2,RBM17,CSNK2A1,H3C1,CEACAM5,KPNA2,CAPZA1,RDH11,FKBP8,ZBTB25,CLPB,CDK8,TMEM165,SLC25A24,TSPAN3,STRBP,MTCH2,TP53,APOO,ZMYM4,CYP27A1,STAT2,NDFIP1,FBXO22,PSMB6,ACAP2,ALG5,APEX1,VDAC2,VMAC,ZMYM2,SF3B4,SPCS3,RBBP8,PIWIL4,PRSS1,RCL1,MYC,HNRNPAB,TRA2B,SRSF2,SOX3,TRIM52,RFC4,SNRPA,SMARCD3,AKAP1,DR1,RAP2A,GSTM2,EIF4B,RPP21,HNRNPL,RAB1B,MEAF6,FAM98A,TMEM97,CCT7,PCDH9,EED,S100A8,PPFIA3,AK2,CASP12,NCK1,YWHAB,HSPB1,BAZ1B,RAB5C,YWHAG,CTNNB1,KRAS,DCP2,VDAC1,RUVBL1,HNRNPDL,RBM3,TRIM21,RUVBL2,RTCB,TUBB4B,H2BC1,RHOBTB1,TAF10,MAX,TOP3B,PTS,HEXA,FBXL7,H1-3,ELF1 |
| 2.940e-07 | -15.04 | STAT6 (signal transducer and activator of transcription 6) | protein interactions | 6778 | 82 | 45 | 19454 | 5460 |
JUN,EEF1A1,TP53,PGGT1B,RAD23B,JAK1,DHX9,FKRP,IFNG,RIGI,AHCYL1,PDE12,API5,NFKB1,IRF4,TRAF6,DSTN,IGBP1,RB1,ZBTB2,EHD1,STAT6,PPARG,WWP1,RLIM,EP300,NUBP2,PPM1G,INPPL1,LITAF,USP8,FBXO7,IFNAR1,CREBBP,GFUS,PKNOX1,TRIM24,SRXN1,SH3BGRL,SRC,APEX1,NMI,CEBPE,STAT2,ACTB |
| 2.948e-07 | -15.04 | MRPL4 (mitochondrial ribosomal protein L4) | protein interactions | 51073 | 272 | 115 | 19454 | 5460 |
ZMYND19,TUFM,TRIM23,TEX19,RC3H2,DNAJC19,UBE2H,YPEL5,MRPL53,CCNF,CINP,RBFOX2,RBMS2,MRPL10,MTRES1,KLF4,CYC1,GID8,GID4,RPA3,GFM1,MRPL40,MRPL41,MRPL17,MRPL20,NHP2,GRSF1,CSNK2A1,SNRNP70,CHCHD1,TMEM70,RPS2,SSBP1,PRR3,MRPL50,PRNP,FZR1,CAND1,MRPL24,SLC25A12,MALSU1,MRPL11,MRPL47,GNPNAT1,METTL15,APOBEC3D,AURKAIP1,NEFL,MRPL51,MRPL49,GFM2,MRPL33,MRPL52,RPL17,MRPL22,FASTKD5,MEPCE,CFAP20,CUL3,PMPCA,MTG2,AUH,MYC,MRPL16,FBXW11,HTRA2,MCAT,RIT1,MTG1,CCDC90B,ACKR3,TACO1,MRPL13,MRPL23,APEX1,RPL19,PRRC2A,ESR2,RPL27A,MRPL12,ELK4,MRPS18A,EXD2,NGRN,RMND5B,HSPA8,MRPL34,MRPL57,TRA2B,HSCB,RANBP10,SAV1,MTRF1,TRA2A,ATG7,HNRNPA1,MRPL9,RHOG,MRPL18,ARMC8,MRPS26,HNRNPD,RPL8,GATD3,SRSF10,CSNK1E,SOX2,MAEA,HSPD1,PCNA,MKLN1,HINT2,KRAS,H1-6,IMMP2L |
| 2.962e-07 | -15.03 | RBM28 (RNA binding motif protein 28) | protein interactions | 55131 | 336 | 137 | 19454 | 5460 |
SNRNP70,CHCHD1,NOL12,GRSF1,DPP4,PLEKHO1,E4F1,RPS16,CAND1,FZR1,ARF6,CGAS,TOP1,SEMA3C,DKC1,KLF9,SURF6,ZBTB2,SRP14,SYNCRIP,KRR1,LLPH,TFRC,RBM34,ILF2,SRP72,TP53,AURKAIP1,RPL15,PAK1IP1,H3C1,RPS13,RPL17,RIGI,SNIP1,RPL3,RPL23A,MECP2,RC3H2,UBE2H,RPF2,RPL7A,RPS17,RPL26,DNAJC8,PPP1CC,ZNF622,RPL13A,RHOJ,SRPK2,RPL22,RSL24D1,CCNF,ZNF330,EIF2AK2,METAP2,PRKRA,FGFBP1,RBMX2,RPA2,RPLP0,RPL26L1,MACROH2A2,RPS14,FGF13,CDK7,NPM3,DGCR8,FBXW7,RPL4,STK38,UTP23,RPA3,NLE1,SIRT7,RNF113A,MTDH,RAB9A,DDX23,LHX2,DRG1,IFI16,WWP2,MAP3K14,DDRGK1,POLR3F,LYAR,RPL8,CBFB,SRSF1,EED,EZH2,SKA3,HDAC11,SART3,RPL18,RAF1,H1-3,JUN,SOX2,MAK16,ISG15,ELF1,PSMA1,SRSF4,RPL28,RPL31,PPAN,RPS24,LAMTOR1,BRCA1,RHOB,ZCRB1,CDKL2,H1-1,MYC,MTG2,CUL3,GRB10,RAB11A,RPL7L1,SNRNP40,RPL19,RPL10,RPL37A,APOBEC3C,H1-5,SYK,MTF1,BET1,FGF17,UFL1,ZNF692,NOP53,STAU1,COIL,EP300 |
| 2.979e-07 | -15.03 | CREB3L1 (cAMP responsive element binding protein 3 like 1) | protein interactions | 90993 | 204 | 91 | 19454 | 5460 |
GOSR2,BET1,PGRMC1,SEC22A,MRPL12,VAMP1,CTXN3,SMCO4,CMTM7,FAM3C,JAGN1,SPOCK1,EMP3,TMEM203,DDIT3,TLCD1,STX7,VEZT,CYB561D2,PLN,FAXDC2,TMEM229B,PGAP2,NEU1,VAMP2,SEC61G,CTSA,TMEM14B,TMEM147,TNF,LEPROTL1,SACM1L,PLPP6,SYNJ2BP,PLPP4,PMP22,TMEM208,FXYD6,TMEM14A,MFSD5,TSPO2,TIMMDC1,TRAM1L1,SEC22B,PLP2,HACD2,CFTR,TIMM23,TEX264,SLC39A9,ORMDL1,SLC2A3,ENTPD3,SLC7A1,NINJ1,FBXW7,MGST2,CREB3,CSGALNACT2,SLC35B4,PLP1,SYNGR1,CYBC1,MGST3,TECR,INSIG2,UBIAD1,NRM,AGPAT5,TFRC,RUSF1,STX8,TMEM50B,ERG28,NSG1,ADIPOQ,GPR37L1,TSPO,TMEM19,SCGB1D1,TMBIM6,DOLK,TMEM11,ZDHHC15,ADGRE2,AQP2,COMT,COX20,FA2H,ANKRD46,CD99L2 |
| 2.983e-07 | -15.03 | PFDN6 (prefoldin subunit 6) | protein interactions | 10471 | 160 | 75 | 19454 | 5460 |
PTGES3,PFDN1,PDRG1,RUVBL1,DNAAF10,PCGF3,RBBP7,KRAS,DYNC1I1,RUVBL2,RPAP3,EWSR1,POC1B,MOB3C,TUBB4B,RPAP2,ACTR1A,TUBA1A,E2F4,RAF1,ASNSD1,SLMAP,EGLN3,DYNC1I2,FZR1,CEBPG,IGBP1,WDR82,POLR2L,EEF1AKMT3,PPP2CB,DCAF11,SKIC8,DCAF5,TUBG1,SPATA2,PFDN5,WWP2,POLR1H,MBD3,FBXW7,ARHGEF39,NUBP2,PRPF4,RPA3,BAP1,DUSP9,PIH1D1,RPRD1B,POLR1D,RPL10,VIRMA,TNPO3,POLR2B,TUBB,ACTB,SNRNP40,POLR2F,POLR3H,POLR3B,TUBA1B,POLR1B,RIT1,PFDN2,COP1,CDC73,UHMK1,PFDN4,CCHCR1,DCAF4,RC3H2,PPP1CC,TTC33,CUL3,MYC |
| 3.030e-07 | -15.01 | GADD45GIP1 (GADD45G interacting protein 1) | protein interactions | 90480 | 275 | 116 | 19454 | 5460 |
ENKD1,SRSF7,HINT2,PICK1,FBXO11,HECTD3,LSM14A,GADD45A,RPL31,MTMR2,PTRH2,KIF2A,RAF1,HMG20A,GATD3,FAHD1,MRPS26,MRPL18,RHOG,GAS8,MRPL9,HNRNPA1,WWP2,RPL6,RAB5C,KRBOX4,MTRF1,MRPL57,HSCB,TMEM177,MRPL34,TMEM160,NGRN,FOXS1,MRPS18A,MRPL12,RPL27A,RPL10,RPL19,GADD45G,RPL35,MRPL23,RPS9,MRPL13,MTG1,TACO1,PNMA1,GADD45B,MRPS25,FBXW11,MRPL16,PMPCA,MYC,AUH,RPL17,MEPCE,MRPL22,ABCE1,RPL23A,MRPL52,MRPL49,MRPL51,MRPL33,GFM2,NFE2L2,METTL15,AURKAIP1,APOBEC3D,MRPL47,MRPL11,MRPL24,MALSU1,MRPL50,PSMB1,PRR3,SSBP1,TMEM70,SNRNP70,EDC3,GPRASP2,COPS5,UTP23,MRPL20,LDOC1,MBD3,OIP5,MRPL41,MRPL40,MRPL17,RNF113A,GFM1,EXOSC4,MTRES1,TFIP11,MMADHC,PTP4A2,RBMS2,MRPL10,TPT1,TRAF1,IDE,MYG1,RPL13A,TRIM24,CSNK2B,TRIM27,MRPL53,UBE2H,PSMG3,TUFM,AR,CEP70,NTAQ1,FBXO7,RPL26,LRRC73 |
| 3.033e-07 | -15.01 | Mitochondrial protein import | REACTOME pathways | R-HSA-1268020 | 62 | 39 | 10285 | 3229 |
COA4,CMC4,TOMM7,TOMM20,GRPEL1,BCS1L,HSCB,TOMM22,TOMM40,DNAJC19,TIMM23,PMPCA,MTX2,CHCHD2,VDAC1,TIMM21,HSPD1,TOMM70,ACO2,CHCHD3,CHCHD4,SLC25A4,CYC1,SLC25A12,COX19,SAMM50,TAFAZZIN,FXN,TIMM13,ATP5F1A,TIMM8B,TOMM6,GRPEL2,TIMM10,ATP5MC1,COX17,ATP5F1B,TIMM8A,TIMM17A |
| 3.062e-07 | -15.00 | ATP6AP2 (ATPase H+ transporting accessory protein 2) | protein interactions | 10159 | 304 | 126 | 19454 | 5460 |
UBAC2,ATP6V1C1,CD59,SEC22A,NRDE2,SEC62,OTULINL,RND2,EMC1,GDPD3,GOSR1,AZGP1,ATP6V1G1,PACSIN3,STX7,PXMP2,TMEM106B,TMEM203,TMEM185A,RAB5A,LMNB1,LAMTOR1,RIT1,FIS1,SCFD1,RAB11A,CUL3,APEX1,ATP6AP2,LMBR1L,ST8SIA5,SEC61B,RMDN3,RPN1,STIM1,STX12,ETFB,TOP3B,DNAJC25,SERPINA3,KRAS,ZBTB16,FLOT1,FKBP2,TMT1A,OSTM1,SCPEP1,PICK1,RHOG,WWP2,RAB5C,PMP22,PDIA3,CHMP2A,RAB11B,CHI3L1,TMEM97,RAB35,ATP6V1A,S100A8,SSR1,JUP,LMNA,CHRNB2,TIMMDC1,SEC22B,SYNGR2,ATP6V0E1,RABL3,SLC35F6,ST7,CDC42,CD2AP,TMEM106A,CERS2,NINJ1,TMUB1,CHMP2B,DERL1,RAB9A,VIPR1,SYVN1,REN,VAMP5,CREB3,RAB14,COPE,RALA,SEC63,SH3BP4,ENO1,STUB1,VAMP3,DTYMK,CALML5,ACTR2,SFTPC,TFRC,CCDC47,WBP11,MAP1LC3B,MECR,RBCK1,RAB3B,NSG1,FKBP8,ADRA1A,AGA,ESYT1,SLC2A1,ATP6V1D,LAMTOR2,TMEM199,DPP4,LAMP3,ARF6,DNAJC1,TMPO,SLC38A2,LMAN1,SDHB,PTPN1,TES,RAC2,RAP1B,HSD17B11 |
| 3.084e-07 | -14.99 | SNARE complex | cellular component | GO:0031201 | 50 | 32 | 19108 | 5553 |
STX11,VTI1B,CPLX1,SNAP23,NAPA,STX1A,VAMP2,STX17,GOSR2,GOSR1,SEC22B,STX7,STX18,STX8,BET1,STX10,STX16,CPLX3,STX12,NAPG,USE1,VAMP7,CPLX2,SNAP25,VAMP3,BET1L,YKT6,STX5,VAMP1,SNAP29,VAMP8,STX6 |
| 3.112e-07 | -14.98 | NOP58 (NOP58 ribonucleoprotein) | protein interactions | 51602 | 278 | 117 | 19454 | 5460 |
SOX2,NUP153,NCSTN,RPS7,RAF1,E2F4,RPS11,EZH2,CHMP4C,PDHA1,RUVBL2,RPAP3,RPS24,UBE3A,TRIM11,RPL31,RPS4X,G3BP1,KRAS,RUVBL1,CDK20,VDAC1,GNL1,XPO1,DDRGK1,IFI16,RPL6,WWP2,POU5F1,DDX23,AGR2,EED,PHB1,DHX15,POLR3F,NOP58,RPL7,SUMO2,PIH1D1,PPARG,MAP2K1,HSPA8,EP300,COIL,B9D2,UFL1,STAU1,BTF3,MYC,CUL3,SERPINH1,RIT1,FTSJ3,LMNB1,DCAF4,ATG3,RPL37A,DLST,ZNHIT6,ESR2,RPL10,MAD2L2,RPL19,APEX1,SNRNP40,HBP1,AP1S2,NUPR1,HSD17B10,EMC2,TCOF1,RPS13,SMN1,KPNA2,NOC4L,CSNK2A1,GRSF1,KPNA1,BRD3,MAP4,H2AC4,CHCHD1,MPHOSPH10,SNRNP70,KRR1,DKC1,ZBTB2,CAND1,IFRD2,FZR1,RPS14,CCND1,UTP15,ACACA,RPA2,LMNA,METTL14,RPA3,BAP1,SIRT7,NHP2,WDR3,RPL4,FBXW7,KPNA6,CIAO1,ATP1A1,UBE2H,RC3H2,ZNHIT3,TXNIP,EIF2S2,UBE2I,PTEN,CCNF,ZNF330,NOPCHAP1 |
| 3.115e-07 | -14.98 | MAP3K5 (mitogen-activated protein kinase kinase kinase 5) | protein interactions | 4217 | 136 | 66 | 19454 | 5460 |
CUL3,SFN,PTPN11,AKT1,CREBBP,TNFAIP3,GADD45B,YWHAZ,FBXW11,FAS,HSP90AA1,STK11,EIF2AK2,STUB1,APOBEC3G,UBE2I,PSMC5,TRAF7,SIAH1,TXN,MAP3K3,TRAF1,VIRMA,JAK2,DYRK1A,PPP5C,SUMO1,PSMC4,CDKN1A,TPD52L1,EP300,TERT,NF2,PSMC1,TNNT2,UBXN6,PIK3R1,MAPK4,GAPDH,YWHAH,YWHAG,TRAF6,BRD3,YWHAB,RB1CC1,MAP2K6,EEF1AKMT3,AIFM1,CDK6,FZR1,EGLN3,GLRX,CDK4,TOP3B,RAF1,TULP3,SOCS3,TRAF2,MAP2K3,PRKAG1,TNFAIP8L1,PSMC3,IGF1R,TOLLIP,SMN1,DUSP19 |
| 3.127e-07 | -14.98 | SBF1 (SET binding factor 1) | protein interactions | 6305 | 144 | 69 | 19454 | 5460 |
YWHAG,YWHAH,SUV39H1,DDRGK1,HENMT1,UBXN6,TLE1,DNAJC7,HSPB1,RHOG,RAC2,HRAS,RAB35,EEF1AKMT3,EGLN3,TRMT61A,CX3CL1,ARF6,GFOD1,RHOH,PRNP,TULP3,ZNHIT1,TOP3B,MTMR2,RND3,TNFAIP8L1,PNMA2,RAB6B,EFNB1,RPAP3,IFT52,UQCC2,TFPT,PSME1,PTGES3,SSRP1,KRAS,CRYBA4,TGFBR2,DNAJC5,MYC,COL1A2,MRPS16,FBXW11,RHOB,PPM1M,CRYBB3,LURAP1,CTTN,CIB2,CTTNBP2NL,ESR2,MANSC1,RHOJ,IGFBP3,CDC42,RND2,CDKN1A,NEK7,RPA2,FGFR1,RHOU,SIRT7,TRIM52,WDR55,FTL,SLC31A1,STAU1 |
| 3.132e-07 | -14.98 | response to inorganic substance | biological process | GO:0010035 | 505 | 201 | 18204 | 5365 |
ATF1,TUBA1A,KRT8,SUMO1,GSK3A,KCNIP2,MAP1LC3A,CCS,SLC25A24,CPNE2,STAT1,PPP5C,ATP2B4,RASGRP2,SOD1,ATP1A2,CYP1A1,HBB,BECN1,KIT,CD14,MTF1,GRIA1,SELENOV,IL18BP,GPX1,MT3,TF,KCNMB1,TXN,BAK1,MAP1B,AANAT,PCNA,TNFAIP3,CYP2R1,ADD1,SLC1A1,CALR,IL1A,SLC6A3,UCP2,DPEP1,CRIP1,MT1E,OSER1,AMELX,DDI1,STAT6,CCR7,RTF2,ACO1,GLRX2,AKT1,AIFM1,SLC6A1,PPP3CA,GCLC,SELENOM,KCNH1,MEF2C,HP,BAP1,FKBP1B,TXNIP,AQP2,MCOLN1,CAV1,ADSS2,FABP4,NUDT1,DTYMK,TXNRD2,CLDN1,FXN,AQP3,CPNE1,TACR1,KCNMB2,MIR342,TLR9,PLCB1,PRDX3,CRYAB,BGLAP,MMP9,MIR107,IL6,AHCYL1,CREB1,UBE3A,HNRNPA1,GLRA1,KCNB1,KCNC1,IMPA2,NEUROD2,CSF2,MT1X,PRNP,SOD3,TRPC1,CDK1,JUN,ATP5F1A,JUNB,PPP2CB,ADNP,ALOX5AP,OGG1,CYP11B1,ANKH,GUCY1B1,TERT,MT1M,ATP5F1D,EIF2S1,GLRA2,HSP90B1,FOS,SLC11A2,PPIF,HSD17B1,NPTX1,PLSCR1,CCL19,CUTA,VPS54,MT2A,SLC12A2,CYP1B1,G6PD,NEFL,TFRC,RPS3,EIF4A3,TRAF2,HNRNPD,CYBRD1,CRHBP,KCNJ10,CYP11B2,RHOB,S100A8,FBP1,HDAC6,KCNMA1,HFE,TOP2B,SLC41A1,EZH2,SLC38A2,NCSTN,B2M,GPHN,ALPL,MECP2,FGF23,NFE2L2,MT1A,MNAT1,NSMCE3,CCNA2,STIM1,CAPN2,SLC25A12,SELENOW,CDKN1B,NQO1,ALG2,TSPO,NEK7,SOD2,MEF2A,CYGB,HPCA,HBA1,NLGN1,TP53,TNNT2,CLIC4,MDM2,SLC13A5,PIK3CA,DLG4,CER1,ATF4,BACE1,SLC25A23,SELENOP,KLF4,FIBIN,HOMER1,HSPA8,SRC,ADORA1,PRDX2,PCGF2,COMT,FGFR1,PRDX1 |
| 3.150e-07 | -14.97 | MRPL24 (mitochondrial ribosomal protein L24) | protein interactions | 79590 | 207 | 92 | 19454 | 5460 |
SRSF4,IMMP2L,HINT2,COX8A,HSPD1,RPS11,RPL18,PDHA1,SOX2,GATD3,FAHD1,RPL8,MRPS26,MRPL18,RHOG,MRPL9,HNRNPA1,DDRGK1,MTRF1,RPL6,HSCB,TMEM177,NGRN,EXD2,MRPS18A,MRPL12,RPL27A,RPL10,RPL19,MRPL23,RPL35,RPS9,MRPL13,TACO1,MTG1,RPS5,HTRA2,PSKH1,MYC,AUH,MTG2,PMPCA,CUL3,MEPCE,MRPL22,FASTKD5,RPL17,ERLEC1,EMC2,SNIP1,MRPL52,MRPL33,ILF2,GFM2,MRPL51,AURKAIP1,APOBEC3D,METTL15,TBK1,MRPL47,TP53,MRPL11,MALSU1,SLC25A12,CGAS,MRPL50,PRR3,SSBP1,RPL32,TMEM70,SNRNP70,CHCHD1,GRSF1,ABCC2,RPS15,NPM3,MRPL41,MRPL40,GFM1,HEXIM1,DYRK2,ZNF574,MTRES1,RPA2,MRPL10,RBMS2,SMYD3,RPL13A,MRPL53,UBE2H,RPL26,TUFM |
| 3.150e-07 | -14.97 | ZFP36L2 (ZFP36 ring finger protein like 2) | protein interactions | 678 | 207 | 92 | 19454 | 5460 |
RPS15,STK38,SQSTM1,BANF1,SPTBN1,RPL22,LDHA,TXN,RPS3,CTNNA1,ENO1,TUBA1B,IRF6,EIF3G,IVNS1ABP,CFL1,NONO,RPS13,HSPE1,THRAP3,HNRNPK,HAPSTR1,POLR2G,JCHAIN,TLCD3B,RPL15,TMPO,RPS16,MIF,SYNCRIP,BRD3,GAPDH,MOV10,HSPA8,DDX5,HADHA,ATP2C1,EIF4B,MYL6,MRPL12,ESR2,ATP5F1B,TAGLN2,AKR1C2,TUBB,RPL35,PRMT5,MAB21L1,S100A6,DLST,HSP90AA1,RPS5,PRSS1,FYTTD1,YWHAZ,SFN,CUL3,HNRNPAB,LDHB,RPS4X,PRPS1,HNRNPDL,FLOT1,G3BP1,KGD4,PRPSAP1,FBXO11,TRIM21,RPS24,HSPD1,PABPC1,HNRNPA2B1,ZRANB2,RPS11,TPPP,PLS3,NME1,EEF2,RPS7,TOP3B,PPIA,HNRNPL,RPS10,CCAR2,RPLP1,RPLP2,YWHAB,PPIB,YWHAH,YWHAG,XPO1,PRDX1 |
| 3.187e-07 | -14.96 | positive regulation of leukocyte proliferation | biological process | GO:0070665 | 164 | 79 | 18204 | 5365 |
NCK1,RPS3,SELENOK,IL13,TFRC,CD86,IL21,IL6,GPAM,FGF10,NMBR,SLC7A1,ST6GAL1,XCL1,IL12B,SLC39A10,IL1A,CD209,CCL5,IGF1,CD40LG,LEP,TLR4,PYCARD,PELI1,AGER,IL6ST,CSF2,IL1B,CD40,DHPS,IL12A,FOXP3,CD274,BCL6,PPP3CA,IL18,PNP,RAC2,MIF,HMGB1,SASH3,CD1D,CHRNB2,MEF2C,IL7,CD28,CD80,IL23A,TIRAP,CDKN1A,IL34,BST2,IL15,TICAM1,EPO,JAK2,IL2RA,BCL2L1,IL5,CD81,PDCD1LG2,MIR30B,MIR21,IL2,CCR2,TGFBR2,AIF1,CCL19,EFNB1,CD46,IL4,KIT,TRAF6,MYD88,TACR1,PRKCQ,TLR9,CD38 |
| 3.220e-07 | -14.95 | ELOVL5 (ELOVL fatty acid elongase 5) | protein interactions | 60481 | 360 | 145 | 19454 | 5460 |
APLNR,ATP6AP2,ARF1,DPEP1,SLC38A1,SCFD1,VMP1,FAM219A,GCC1,LMNB1,VEZT,RAB11A,STX7,UFL1,GOSR1,TIMM17A,BET1L,ATP2C1,ARCN1,TMEM115,VAPB,YIPF5,SEC62,RAB6A,GINM1,GOSR2,PGRMC1,BET1,NOTCH2,TOR1AIP2,GJA1,SGMS1,STX5,CYB5A,RPL8,C2CD2L,SLC20A1,CDK5RAP3,DDRGK1,SYNJ2BP,PTDSS1,TSPAN10,SLC35A2,RETREG1,SAR1B,EMC8,SEMA4C,JAK1,TMEM87A,RINT1,CRELD1,TAPT1,CYB5B,STIM1,VAMP2,FAF2,TMEM59,YIPF3,IFNGR1,STBD1,MACO1,ARFGEF1,TECR,ROMO1,SEC63,SLC25A4,STX10,VAMP3,NECTIN2,LRP6,EPHA2,ATP1A1,SNX5,ARFGAP3,DEPDC1B,HMOX2,GORASP2,TMEM209,YKT6,CERS2,SLC7A1,RPL4,SPCS2,MTDH,RTN4,ARFIP1,TMEM243,TEX264,SLC39A9,PDCL,VPS54,LEMD3,LMNA,SYS1,USE1,SSR1,GOLGA5,SLC12A2,TMX4,PLP2,RABL3,UBA52,ARHGAP1,SEC22B,LMAN1,SLC38A2,TMPO,CAV1,DNAJC1,ARL6IP5,COG1,CDCA3,PTPN1,HACD3,SRPRA,CAMLG,OSBPL8,AGPAT1,SLC2A1,POR,SMIM12,ESYT1,HM13,EI24,TMEM199,DHRS7,SLC6A8,FKBP8,TMEM33,SRPRB,RPL3,STX18,BSCL2,TMX3,NSDHL,FAM169A,TFRC,SURF4,TMEM165,LBR,H2AX,UBIAD1,SNAP29,CCDC47,PREB |
| 3.233e-07 | -14.94 | NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9) | protein interactions | 4704 | 313 | 129 | 19454 | 5460 |
NDUFA12,PDHA1,NDUFS6,DNAJC25,RAF1,IMMP2L,EMC8,KRAS,VDAC1,HINT2,NDUFB5,HSPD1,SDHC,NDUFA4,MRPS26,NDUFB8,RHOG,SKIC8,AGR2,XPO1,NDUFV2,MTRF1,MAPK4,EGLN3,NDUFS8,COX14,RMND1,CORO1C,GATD3,ATP6V1A,PHB1,PIH1D1,NDUFA5,KLF3,ATP6V1C1,TOMM22,HSCB,NDUFS2,EMC1,PHB2,NMRAL1,HADHA,EMP3,NGRN,EXD2,TOMM40,BTF3,MYC,NDUFB7,AUH,COX6B1,MTG2,NDUFB6,PMPCA,CUL3,APLNR,IREB2,ACAP2,MAD2L2,MTM1,ATP5F1B,LMBR1L,TACO1,VDAC2,CCDC90B,MTG1,GFM2,NDUFS3,APOO,AURKAIP1,METTL15,ATP5PB,MRPL11,NDUFA2,MTCH2,FASTKD5,DNAJC30,SFXN1,POR,CHCHD1,TMEM70,HDAC6,CALR,GRSF1,LAMTOR2,MYL12A,ARL6IP5,NDUFA1,SDHB,SSBP1,AIFM1,NDUFB4,COMT,COX4I1,CYC1,MTRES1,COX6C,RPA2,PTPN22,SSR1,HSP90B1,UQCRC1,NDUFAB1,CFTR,TIMMDC1,TPT1,ABCC2,CRYZ,KDM1A,PDHB,PGK1,GFM1,NDUFC2,DVL2,MME,RPA3,NRP1,DNAJC19,ATP1B3,RC3H2,ATP5F1A,TUFM,NDUFB10,UQCRQ,VIRMA,MGST3,GMDS,CYBC1,UQCRC2 |
| 3.260e-07 | -14.94 | SOCS1 (suppressor of cytokine signaling 1) | protein interactions | 8651 | 163 | 76 | 19454 | 5460 |
TUBB,YES1,JAK2,SRC,PTEN,MRPS28,SNRPD1,CCT2,PIM2,HSP90AA1,CUL2,IL2RB,PTPN11,SLC25A1,USP13,IFNAR1,RPL39,PRKACB,HMGB1,PIK3R2,IRF7,ASB3,IRF3,CXCR4,TRIM5,HSPA8,VAV2,SLC25A3,MET,SPTBN1,WSB1,ATAT1,TIRAP,TCP1,CAND1,HSP90AB1,PPIA,SSBP1,ETV6,ITK,TRAF6,NCK1,PDCD1,TUBG1,OSBPL8,HSPB1,DICER1,AKAP8L,TRIM8,PIK3R1,CTNNB1,ELOC,IGF1,THRAP3,KIT,PRPS1,SOCS2,NDUFA4,CCT8,CLEC7A,SLC25A5,S100B,BAG2,HSD17B10,IGF1R,PRPSAP1,JAK1,ABCE1,JOSD1,TUBB4B,CRKL,GHR,TP53,CCT5,PTS,IFNGR1 |
| 3.318e-07 | -14.92 | COA7 (cytochrome c oxidase assembly factor 7) | protein interactions | 65260 | 123 | 61 | 19454 | 5460 |
PCNA,EFHC1,CLPB,GPSM3,ABCF1,SFXN1,ENKD1,MDC1,IMMP2L,GUK1,KRAS,DNAJC30,TRIM63,APOO,HOXB1,PGM1,MSRB3,PDHA1,SDHAF2,AIFM1,FAM219B,COX4I1,EGLN3,SLC25A12,PLGRKT,COX14,CRHBP,ACOT8,DNAJC4,FBXO34,HSPB2,ACP5,PRDX6,TXNDC17,TIMP3,SLC25A51,PHB2,TIMM29,LAP3,FKBP10,LMNA,PAK5,IDH2,OPTN,PARL,CLIC4,LYZL6,FBXO22,B4GALT3,MTPN,COX11,ISCA2,SNRPB,ACO2,PMPCA,FXN,RIT1,HTRA2,GLOD4,CHCHD4,PSMD14 |
| 3.329e-07 | -14.92 | Hh mutants abrogate ligand secretion | REACTOME pathways | R-HSA-5387390 | 60 | 38 | 10285 | 3229 |
UBB,PSMD4,SYVN1,RPS27A,UBA52,PSMA1,DERL2,PSMD14,PSMC3,PSMD7,SEM1,PSMB9,PSMB4,PSME1,PSMD6,PSME2,PSMD10,PSMA6,PSMB3,PSMB6,PSMA2,PSMB2,PSMD1,PSMB10,PSMA5,PSMC5,PSMB11,PSMA4,PSMC1,PSMC4,ERLEC1,PSMD12,PSMB5,PSMA3,PSMB1,OS9,PSMB7,PSMD3 |
| 3.329e-07 | -14.92 | CDT1 association with the CDC6:ORC:origin complex | REACTOME pathways | R-HSA-68827 | 60 | 38 | 10285 | 3229 |
PSMB1,PSMB7,MCM8,PSMD3,PSMC4,ORC5,PSMC1,PSMD12,PSMA3,PSMB5,PSMB10,PSMA5,PSMB11,PSMC5,PSMA4,PSMA6,PSMB3,PSMD1,PSMB2,PSMA2,PSMB6,PSME1,PSMB4,PSMD6,PSMD10,PSME2,ORC6,PSMD7,SEM1,PSMB9,PSMA1,GMNN,PSMC3,PSMD14,PSMD4,UBB,RPS27A,UBA52 |
| 3.347e-07 | -14.91 | BSCL2 (BSCL2 lipid droplet biogenesis associated, seipin) | protein interactions | 26580 | 185 | 84 | 19454 | 5460 |
CXCL9,PLEKHF2,ANKRD46,HNRNPL,LHFPL1,MSMO1,SLC25A17,PHB1,HAS3,SPMIP9,RPRM,MFSD5,AGR2,DEGS1,FITM2,UPK1A,NUS1,TMEM164,ICAM2,SLC25A46,TMEM19,FAM20B,ORMDL3,DNAJC30,NSG1,RHBDD3,PGAP4,YIF1A,TSPAN17,SLC39A3,SFTPC,SLC35F1,SLC25A24,TSPAN3,IL20RB,RNF121,METTL15,GABARAPL1,YIPF3,CD47,SC5D,TRIM54,LRRC8A,B4GAT1,CLRN2,SCAMP2,ELOVL4,VAMP3,GPR89A,ENDOD1,TLR9,CD226,SYP,GABRG2,TMEM41A,LHFPL6,DEPDC1B,ATAD1,SLC25A51,GOSR1,TLCD1,CERS6,TSPAN5,TICAM2,ZDHHC17,CLDND1,TMEM106B,SLC35F2,DERL1,GP9,USE1,TMEM115,TMEM95,LMBRD2,IFRD1,CHRNB2,CMTM7,TRAM1L1,FUT8,ADIPOR1,GJC1,ST7,HACD2,GLRA2 |
| 3.366e-07 | -14.90 | Psmb5 (proteasome (prosome, macropain) subunit, beta type 5) | protein interactions | 19173 | 63 | 37 | 19454 | 5460 |
PSMB7,TIMM23,PSMC3,PSMC4,PSMB3,YIPF5,PSMA2,PSMA5,PSMA1,PSMD12,TOMM20,PSMC1,PSME1,CRY1,UBE3A,HSD17B10,PSMA3,PSMG2,PSMD7,PSMD14,UBFD1,PSMB2,PSMD3,PSMA4,FBXO7,PSMD1,PSMD4,MEAF6,ADRM1,B4GALT4,PSMB6,PSME2,PSMB4,PSMA6,PARP2,PSMC5,PSMB1 |
| 3.366e-07 | -14.90 | TACR1 (tachykinin receptor 1) | protein interactions | 6869 | 63 | 37 | 19454 | 5460 |
LPCAT3,CERS2,TMEM147,NDUFC2,PLSCR1,NDUFB5,TSPAN15,CAV2,TSPAN3,LMBRD2,SIGMAR1,NDUFS6,GOLGA5,YIPF3,CCDC167,HACD2,SYNGR2,ATP5PB,TMEM126A,ADIPOR1,VKORC1L1,ATP5PD,SLMAP,CAV1,ARL6IP5,ADCK1,ATP5F1B,TAC1,MFSD5,GPR89A,TMEM164,NDUFB8,ATP1A3,ENDOD1,ATP5F1A,SLC25A46,PKP4 |
| 3.392e-07 | -14.90 | ITGB1 (integrin subunit beta 1) | protein interactions | 3688 | 322 | 132 | 19454 | 5460 |
SNX17,GJA1,CD63,RAB35,DIRAS3,RHOH,HNRNPL,RAB5C,PIK3R1,PDIA3,LAMP2,CD58,YWHAB,RHOG,ARHGAP5,COX8A,PICK1,TMT1A,HSPD1,SAR1B,RAB8B,TSPAN11,TRIM37,G3BP1,KRAS,ARL5B,ACTN4,TUBA1A,DNAJC25,RAF1,CRKL,PLD3,RND3,RAB4A,NME1,CHMP4C,RPN1,EZH2,STIM1,SEC61B,LGALS3,RFC5,RAB11A,EPS8,CUL3,RIT1,ILK,LMNB1,RHOB,LAMTOR1,RAB5A,TMEM106B,STX7,ITGAV,PXMP2,GPC1,EMC1,HSCB,SEC62,RND2,OTULINL,CLDN4,PIH1D1,CSNK1A1,RAC2,HSD17B11,DSTN,ITGA6,HRAS,PTPN1,SMAD3,CAV1,STX6,TMPO,LMAN1,ARF6,DNAJC1,CD151,DAG1,CD81,LAMP3,CD36,DPP4,FBXO34,ESYT1,SHC1,CD9,SPP1,IGF1R,EMC2,RAB13,RAB3B,TOLLIP,AGER,ENO1,SEC63,VIRMA,FERMT2,RHOJ,PRKCE,CD47,DNAJC5,RAB2A,CALU,CDC73,NCKIPSD,EPHA2,LGALS8,RAB9A,DERL1,ITGA2,SYVN1,PML,RHOU,RPA3,HSPA5,MEF2A,FBXW7,PDHB,NF2,ST7,CFTR,CDC42,ACACA,PRKCA,ARL15,MET,SSR1,PICALM,CD46,LMNA,RPA2 |
| 3.397e-07 | -14.90 | regulation of vascular endothelial cell proliferation | biological process | GO:1905562 | 54 | 34 | 18204 | 5365 |
MIR24-1,CCL2,MIR29C,MIR133B,MIR200C,MIR34A,MIR29A,MEF2C,MIR150,MIR135B,MIR424,DBH,MIR126,MIR129-1,APLN,MIR30E,MIR132,AKT3,PROK1,MIR193A,GHRL,HMGB1,MIR495,FGFR1,MIR492,MIR21,MIR30B,SLC39A9,MIR152,MIR503,PPARG,MIR130A,MIR98,SP1 |
| 3.399e-07 | -14.89 | MAP2K1 (mitogen-activated protein kinase kinase 1) | protein interactions | 5604 | 264 | 112 | 19454 | 5460 |
PEBP1,BMPR1A,HSPA8,EP300,HSCB,MLH3,TOMM22,RPE,PPARG,MAP2K1,HEXB,CSNK1A1,PAPSS2,LAMTOR3,PSMB6,RPL10,MYC,GRB10,MCM3,MCM4,YWHAZ,PSMD14,RPS6KA4,RHOB,BAX,HSP90AA1,OSGEP,TRIB1,DNAJB6,MAP3K11,ABCF1,PCNA,CDK5,ZC3H7A,PSMA1,KRAS,HNRNPDL,RAF1,RPL29,SKA3,RPS23,RPL8,THOC2,ODC1,NOP58,RPL7,ELK1,WIF1,HSP90AB1,HMGA1,RAB5C,HNRNPA1,YWHAG,YWHAH,NT5C2,PSMD10,TRAF6,HNRNPD,YWHAB,HSPB1,DVL2,RPA3,TLR2,PRDX6,NPM3,STK38,HMGB1,FBXW7,WDR83,TPT1,CAPN1,ING5,RPA2,JUP,OPTN,CTNNA1,UBE2I,CTSB,SRC,PTPN11,RPL7A,BRAP,ATP5F1A,STK11,SMAD2,MAP1B,IGF1R,AKAP12,RNASE9,HNRNPK,WASL,TGFBR2,TUSC3,MSH6,PIK3CA,CBX3,NFE2L2,HRAS,KRR1,MAP2K6,DNAJC1,CPNE1,PLEKHF2,CAND1,RPL35A,TMPO,G6PD,SLAIN2,FAM20C,LAMTOR2,CCL4L1,CD9 |
| 3.427e-07 | -14.89 | SREBF2 (sterol regulatory element binding transcription factor 2) | protein interactions | 6721 | 290 | 121 | 19454 | 5460 |
FTL,AZGP1,ZDHHC17,ATAD1,SRM,RER1,TTC1,EP300,FDFT1,SKA2,BEND6,RPP21,PRKAB1,APEX1,PARL,PSMD4,DKK3,ZMYM2,OR9I1,SF3B4,PELO,LMBR1L,WNT10B,CD79B,PAPSS2,HTRA2,FIS1,CRMP1,SP1,BAX,SLC7A11,CGRRF1,H1-10,MCM8,MRM2,TMED5,CREBBP,NFYA,SACM1L,RBBP7,FHL3,ATP6V0B,TMEM268,FGF3,ZYX,CYP2C9,SLC4A8,PDHA1,ZC4H2,SKA3,LGR4,ERLIN2,TMEM59,CFAP97D1,OS9,RAB11B,OSBP,HNRNPL,MEAF6,SPINT2,AZIN1,EED,KCNA2,DICER1,RNF139,KDM2A,EMC6,MTRF1,PRDX1,INPP4A,HSPA5,PIAS1,FBXW7,HDAC3,ACACA,HEXIM1,CHRNB2,GP9,SYS1,HCST,FAXC,TMEM106A,SUMO1,SPTBN1,VIRMA,SMURF1,SC5D,ZNF655,UBE2I,CREB1,SLC25A39,TPPP3,CDKN2AIP,UBE2H,DNAJC19,NR0B1,SUB1,SLC25A1,RIGI,MSH6,VPS16,EGR1,HNRNPK,HAPSTR1,CLPB,TGIF2,GLUL,NAE1,OTX2,AGPAT5,CCT5,INSIG2,HINFP,KMT5B,MARCHF4,LDLR,GATAD1,EIF4E2,SMAD3,COPS5,EMC4 |
| 3.429e-07 | -14.89 | MTRFR (mitochondrial translation release factor in rescue) | protein interactions | 91574 | 227 | 99 | 19454 | 5460 |
NDUFV2,MRPL9,RAB5C,MRPS35,STOML2,HMGA1,CLPX,DDX50,MRPS26,MRPL18,NDUFS8,SRSF10,HNRNPL,ETFB,NDUFA12,NDUFS6,PDHA1,NUDT19,MRPS11,HINT2,PREPL,HNRNPDL,SSRP1,MRPS17,KGD4,ETFA,MRPL16,HNRNPAB,PYCR1,MRPS25,NOA1,MRPL13,MTG1,DLST,TACO1,NDUFAF4,MRPL23,MRPL12,NDUFA5,MRPS18A,HADHA,MRPL34,NGRN,MRPS7,COIL,MRPL57,NDUFS2,TRA2B,COX5A,GRSF1,ALYREF,MRPS9,MRPS23,MRPL24,DBT,MRPL50,METTL15,BCS1L,HADH,PPIF,NDUFA2,MRPL47,MRPL49,MRPL51,NDUFS3,HSD17B10,MRPS18B,MRPL52,MRPS18C,MRPL22,HSPE1,HNRNPK,MRPS33,PYCR2,RPF2,NDUFAF2,MRPS16,ACAT1,MRPS28,EIF2AK2,VAMP3,MRPL53,MRPS21,MRPL10,NDUFAB1,MTRES1,HNRNPH3,MRPS34,QRSL1,DLAT,GFM1,TWNK,MRPL20,POLDIP2,MRPL41,MRPL40,NME4,PDHB,MRPL17 |
| 3.447e-07 | -14.88 | TDRKH (tudor and KH domain containing) | protein interactions | 11022 | 75 | 42 | 19454 | 5460 |
MTARC2,GGCT,TOP3B,TOMM22,MTCH2,E2F4,MTX2,PTRH2,LCN1,MAVS,RAB5A,AKAP1,EXD2,TOMM20,PXMP2,AZGP1,FKBP8,HSCB,PHB2,RAB3B,PIWIL1,GPRASP2,NONO,SLC25A46,FAM193B,MARCHF5,PEX3,PIWIL4,FIS1,ARHGAP19,LANCL2,RMDN3,AIFM1,PTPN1,SRSF1,KTI12,UBE2N,COX14,PLGRKT,ESR2,SELENON,MGST3 |
| 3.449e-07 | -14.88 | OLA1 (Obg like ATPase 1) | protein interactions | 29789 | 131 | 64 | 19454 | 5460 |
ALYREF,PHB1,LDLR,CAV1,HMGA1,WWP2,COPS5,GAPDH,TUBG1,AGR2,SNRNP70,HSPB1,MORC2,SNIP1,EWSR1,UBE3A,KRAS,HUWE1,LSM4,UBE2A,SAR1B,RIGI,RAD21,RAF1,TXNRD1,TP53,NDUFA2,SOX2,EZH2,SNRPE,SART3,RNF8,STUB1,CCNF,EFHD2,PRMT5,TXN,RAB14,NDN,YES1,TUBB,ACO2,PRPF31,BAG3,YWHAZ,BRCA1,MAPRE1,UBE2H,RPA3,PRPF4,PPIH,EP300,RAB5A,STAU1,BCL6,LSM8,CDC42,STXBP1,NEK7,LMNA,RPA2,RPL26L1,LEMD3,SHOC2 |
| 3.449e-07 | -14.88 | GTF2E1 (general transcription factor IIE subunit 1) | protein interactions | 2960 | 131 | 64 | 19454 | 5460 |
TRIM15,KCTD10,SNRPD3,NDUFB4,GTF2B,XPO5,IKBKB,GTF2A2,MED21,DDX23,RPL23,TAF7,ERCC3,GTF2E1,H3C1,PPWD1,SNIP1,EWSR1,CDK8,CBX3,POLR2G,SMARCB1,TP53,RRM1,GTF2E2,TRIM29,MED17,COPE,TAF11,SRPK2,ERH,PSMB6,POLR2B,ZNF330,GTF2F1,TRIM24,GTF2H2,GTF2F2,GTF2A1,BRCA1,FAS,RIT1,SETD7,CARS1,DRAP1,BTF3,EEF1G,FBXW7,RBM22,CMAS,COIL,PML,SLC39A9,NUP50,TCEA1,TTC1,EXOSC4,LMNA,CDK1,GTF2H5,SH3GLB2,GTF2H4,CDK7,ZSCAN1 |
| 3.457e-07 | -14.88 | GTPBP4 (GTP binding protein 4) | protein interactions | 23560 | 402 | 159 | 19454 | 5460 |
DDX23,WDR12,LHX2,DICER1,DRG1,IFI16,RPL6,YWHAG,DDRGK1,NOP58,RPS10,FAM98A,LYAR,RPL8,MRTO4,FBXO32,SRSF1,EED,PNMA2,SART3,RPL18,RAF1,MAGEB10,SOX2,MAK16,G3BP1,H1-6,KRAS,HMGN4,RPL28,RPL31,FGF3,PPAN,RPS24,PSKH1,LMNB1,DCAF4,RHOB,MYO6,DNAJB6,RIT1,H1-1,NSA2,MYC,RAB11A,GRB10,ZNF668,MATR3,RPL35,RPL7L1,SPCS1,RPL19,RPL10,APEX1,RPL37A,PPARG,SYK,MTF1,BET1,UFL1,ZNF692,PSENEN,NOP53,STAU1,COIL,G3BP2,DNAJC22,AZGP1,DDX39B,RAB5A,EP300,DDX5,MPHOSPH10,CHCHD1,SNRNP70,KPNA1,NOL12,RPS2,BRD3,RPL10A,COPS5,RPS16,CAND1,FZR1,DKC1,RBM42,KLF9,SURF6,ZBTB2,SRP14,RCHY1,KRR1,DNAJC2,RBM34,HBP1,ILF2,NUPR1,SRP72,IMP3,PREB,KBTBD4,RPSA,TP53,AURKAIP1,RPL15,H3C1,TGFBR2,MEPCE,RPL17,SNIP1,MRPS18B,RPL3,RPL23A,MECP2,RC3H2,TXNIP,ATP1A1,UBE2H,MAPRE1,RPF2,RPL7A,CIAO1,ANAPC15,NDN,RPL13A,SRPK2,RPL22,CCNF,PSPC1,EZH1,ZNF330,EIF2AK2,METAP2,FGFBP1,PRKRA,RPA2,RPL26L1,RPLP0,ZNF574,MACROH2A2,IFRD1,RPS14,KLF12,CDK7,DGCR8,NPM3,WDR3,RPL4,FBXW7,UTP23,AATF,BRIX1,RPA3,RPL27,SNAPC1,NLE1,SIRT7,RNF113A,RAB9A |
| 3.476e-07 | -14.87 | HIF1A (hypoxia inducible factor 1 subunit alpha) | protein interactions | 3091 | 429 | 168 | 19454 | 5460 |
NQO1,CBL,TRAF6,PSMD10,UBE2D1,IKBKB,CTNNB1,XPO1,LAMP2,HMGA1,HSP90AB1,OS9,ELK1,EGLN3,CCAR2,HNRNPL,XPO5,SIN3A,SART3,RWDD3,FAF2,JUN,PPP2R1A,TUBA1A,RBM38,ISG15,MAX,RFC3,RFC2,RUVBL1,TRIM37,HNRNPF,BAG2,FHL3,MYO1B,RUVBL2,TRIM21,SETD7,DNAJB6,HSP90AA1,ICAM1,SP1,BRCA1,MCM3,OTUD7B,SAMHD1,RFC5,PYCARD,CUL2,PSMA4,MYC,CREBBP,APEX1,POLR2B,UMPS,MATR3,PELO,VEGFA,CPSF1,EPO,MED23,CDKN1A,IDH3B,MYH1,GKAP1,ACTL6A,UNC45A,FBXO30,NSFL1C,RNF5,PCGF2,MED13L,EP300,RLIM,TTC1,HSPA8,HDAC5,SAT1,FOS,XRCC5,CXCR4,RFC4,CLP1,KPNA1,SHC1,EIF5A2,ELOC,HDAC6,COPS5,CSNK2A1,SAT2,TCEANC2,MDM2,NAA11,CDK9,MIF,CAND1,DCUN1D1,FZR1,RB1,CDK6,MCL1,AIFM1,SMAD3,ALDH1A3,FBXO8,PSMC3,RAD23B,ACTR2,CDK8,METTL15,ING1,DDX39A,H2AX,MAP2K3,TP53,CDK4,MSH6,PTGES3,TMEM33,SRPRB,NEDD8,RAB13,FAF1,EPHA2,XPOT,STK11,TXNIP,TUFM,RACGAP1,RHOBTB3,KPNA6,AR,RUNX1,H2BC9,AKT1,VIRMA,EAF2,SRC,EGLN2,LDHA,CTSB,NDN,UBE2I,CREB1,STUB1,HECTD1,CX3CR1,HEXIM1,JUP,CDK1,SMYD3,NTPCR,ELP3,MAFG,CAPN1,SUMO1,UTP23,PIAS1,FBXW7,HDAC3,GTF2I,NF2,SQSTM1,PGK1,NBN,MYH2,BAP1 |
| 3.498e-07 | -14.87 | VAMP4 (vesicle associated membrane protein 4) | protein interactions | 8674 | 139 | 67 | 19454 | 5460 |
STX8,TMT1A,RINT1,TOP2B,STX18,SNAP23,PTGES,KRAS,AP1M1,STX11,SNAP29,DDX39A,MAP1LC3B,TMEM59,TMEM205,RAB4A,ZNF526,STX12,RAB35,SSMEM1,GJA1,STX5,VTI1B,ARF6,NTMT1,STX6,CAV1,LAMP2,ATG9A,RAB5C,LAMP3,CSNK2A1,STX1A,TMX2,RAB5A,RAB9A,GOSR1,NAPG,STX7,FAM234A,RABL3,GOSR2,CFTR,LMNA,CZIB,STOM,USE1,ELOVL4,CYB5R3,CSNK2B,RETREG3,SYT2,STX10,TRIM54,MGST3,REEP4,RAB2A,TM4SF19,COX6B1,SCN3B,RAB11A,MBLAC2,DNAJC5,STX16,LAMTOR1,SCFD1,NAPA |
| 3.499e-07 | -14.87 | COX5A (cytochrome c oxidase subunit 5A) | protein interactions | 9377 | 213 | 94 | 19454 | 5460 |
NDUFS3,ATP5PB,MRPL11,MTCH2,APOO,EXOSC8,DNAJC30,DUSP19,SFXN1,ATP5PF,TMEM70,DNAJC4,COX5A,TPM3,FZR1,HTRA1,PRNP,SLC38A2,ATP5PD,ZBTB2,PLGRKT,SLC25A12,SYNCRIP,SSBP1,AIFM1,COX4I1,COX6C,METTL14,HSP90B1,GSTP1,CYC1,ACACA,PDHB,SLC25A51,HSPA5,ATP1B3,FXN,NDUFB10,GSTK1,ATP5F1A,NONO,TUFM,MGST3,VIRMA,UQCRC2,PTPMT1,PDHA1,COX4I2,G3BP1,GUK1,CHCHD2,VDAC1,ATP5F1D,IMMP2L,NDUFA4,OPA3,HINT2,COX8A,RHOG,MRPS26,MTRF1,COX14,RMND1,NUP35,PHB1,GATD3,CYB5A,MED23,ATP5PO,LAP3,TIMM29,HNRNPA0,HSCB,PHB2,RER1,EXD2,HADHA,PMAIP1,LMNB1,HTRA2,COX6B1,AUH,MYC,MTG2,PMPCA,CUL3,ATP5F1B,ACTB,RPL35,CLIC4,PARL,ESR2,TACO1,CCDC90B |
| 3.538e-07 | -14.85 | AIMP1 (aminoacyl tRNA synthetase complex interacting multifunctional protein 1) | protein interactions | 9255 | 247 | 106 | 19454 | 5460 |
DDRGK1,MAP3K14,MIR29C,WWP2,GSTM3,MIR140,MIR31,MIR214,CORO1C,MIR7-2,PHB1,DHX15,SNRPD3,SUMO2,CCAR2,TRIR,HNRNPL,EIF2S1,ISG15,MIR222,SOX2,TOP3B,RAF1,MOB3C,PNMA2,PDHA1,PLS3,MIR206,PABPC1,CCT8,EMC8,CUL2,PSMA4,MYC,BRCA1,MIRLET7B,SNRPD2,RAN,LMBR1L,MIRLET7D,MAT2B,PSMD6,EIF4A2,BET1,RPL27A,PIH1D1,EMC9,EP300,NMRAL1,HSPA8,G3BP2,EMC1,COPS5,KARS1,DPP4,MAP4,MIR34A,TSNAX,MIR25,UBE2N,MIR106B,RPL15,MIR15A,COMTD1,RNF8,MIR17,RPL23A,GLUL,MAP1B,RAB1A,RPL17,MIRLET7C,MEPCE,USP14,TUFM,ATP5F1A,RPL7A,MAT2A,UBE2H,SPOP,MSN,OPTN,SRC,VIRMA,HOMER1,FTH1,CFTR,EEF1E1,SPTBN1,MIR34B,MIR7-1,RARS1,RPLP0,METTL14,HSP90B1,SDCBP,MIR34C,RNF113A,MIRLET7I,MIR205,BAP1,MIR107,HSPA5,MARS1,FBXW7,MIR7-3 |
| 3.549e-07 | -14.85 | STT3A (STT3 oligosaccharyltransferase complex catalytic subunit A) | protein interactions | 3703 | 166 | 77 | 19454 | 5460 |
FAM20C,ADIPOR2,EDEM1,COPS5,FAM241A,SLC2A1,ESYT1,RB1CC1,HSPB1,ARMC8,COQ8A,CD274,PHB1,FBXO32,CETN3,RAC2,FZR1,HNRNPL,DERL2,RHOH,KCTD10,EGLN3,COX14,CCDC47,TP53,AURKAIP1,FAF2,MAP1LC3B,TULP3,RPN1,OTULIN,KRAS,PSEN1,FKBP8,OST4,CUL3,RAB11A,TIA1,RHOB,NTRK3,UBE2H,CCNF,LMBR1L,ZNF330,SEC61B,SARM1,RHOJ,ESR2,VIRMA,SEC63,TFEB,PGRMC1,BET1,TPT1,RND2,CDC42,EDEM3,RPA2,GRM2,METTL14,CAV2,HAUS2,RPA3,RHOU,EXD2,TMEM106B,HSPA8,AKAP1,PMAIP1,EP300,RAB9A,HSCB,EMC1,DAD1,COIL,TMUB1,HSPA5 |
| 3.603e-07 | -14.84 | regulation of cellular biosynthetic process | biological process | GO:0031326 | 5616 | 1797 | 18204 | 5365 |
TOP2B,ORMDL3,SSU72,HMG20A,BCL6,SH3BGRL,HFE,PFDN5,CTDSPL2,EMILIN1,ELAVL2,MED11,ITGB8,HINFP,MIR1296,FBP1,LURAP1,TCF19,ZNF511,IL1RAP,MZB1,TWSG1,FGF3,ACTB,HMGA1,TNF,SHMT1,MIR9-2,BRMS1L,XCL1,NAB2,SF3B1,RBPJ,CDK8,AVPR1B,ATP1A1,MIR191,RUVBL1,PDE12,EDA2R,GJA1,MIR17,CNTN1,RBM38,PAIP2B,CEBPG,MIR764,AIF1,FOXC2,NEUROG2,NFYA,RIOX2,CDK9,DRGX,NDN,RBM5,SDR16C5,PHF12,MIR338,NAB1,TYMS,CITED1,RB1,RNF141,CNOT8,MIR99B,PCGF2,CRABP2,TRIP4,SAP18,ZNF574,MIR26B,CIAO3,RAP2C,KLF4,ZBED3,TGIF2LX,ARF4,APLNR,TLR4,ACTL6B,MIR671,CIAO1,MAEL,EPOP,SOST,LEPR,SOD2,NEK7,ZNF362,PCGF6,ZC3H7A,ASCC1,PLGRKT,HELLS,KLHL22,IMPACT,SUV39H1,MLF2,SUFU,RHOG,MIR503,MLF1,MIR212,APOBEC3H,EPCAM,RNF139,ZNF668,MIR638,LUM,HMCES,C1QTNF1,HINT1,RBCK1,APOC2,TRIM44,RPS26,IFRD2,B2M,LHX2,EIF2B2,PRIM2,TCEA2,GTF2I,MSL2,MIR517B,MIR30D,DHX9,RABL3,SPP1,MIR25,UAP1,ISG15,THAP7,MIR1226,ZNF501,BHLHE40,HCFC2,ZNF345,MIR449B,MIR346,NEDD8,RLIM,MIR370,MIR597,LTB,TLE1,TRIM8,IL1R2,SUB1,MIR551B,RGN,EXOSC4,MIR429,STAT2,TOPORS,ZCCHC7,DICER1,DNAJB9,BANF1,IKZF5,SF3B5,IGBP1,CNOT6,MIR215,DLG1,RGMB,IL5,EDF1,TLR7,MIR29C,ZBED1,BUD23,TSN,KDM1A,MIR936,STPG4,TOB2,HDAC5,MIR511,MAP2K1,PPP1CC,HGS,PRMT2,MIR488,ANKRD49,YWHAH,ID1,CCL3,LILRB1,BTN2A2,STOX2,CSF2,RFX4,GTF2F2,IL6ST,BARX2,SRSF12,ZNF322,MIR605,EPHA4,MIR200A,MOSPD1,DEFB124,ZNF821,MIR942,MIR7-2,PELP1,RBM12,CSNK1E,RTRAF,IGF1R,MAGEH1,SFRP1,PPIA,BEND6,SOCS5,IL20RB,HSPA5,MYD88,NPTN,TAF5L,CD46,MIR149,ZNF436,NLRP9,ARPP19,TULP3,CD81,MIR876,FASTKD5,TYROBP,MIR661,ZBTB17,MIR760,MAVS,FURIN,KANSL3,RPS9,TOX4,NR1I3,MED10,ACVR1B,TMBIM6,CD40,MAGEB1,FOXA3,MIR616,NME2,INTS12,MIR208B,SGF29,HDAC6,CREB3,STK11,ALKBH4,MIR592,MED22,CCAR2,NIF3L1,CD2,SPTBN1,TCEA1,ATRAID,TNRC6C,PRKAB1,ASB1,HR,YES1,BIRC2,STAR,MRPL12,GTDC1,MRPL13,CCNH,HNRNPDL,TLR2,RPS13,MIR183,CYP1B1,PTHLH,AKAP8L,RNF10,RNF26,VIP,STAT5A,VRTN,MAP2K6,H2AC25,MRTO4,MIR7-1,MAPKAPK5,ZNF805,NUP62,WBP2,RDH10,MIR16-1,PIH1D1,ZNF575,MIR891B,MIR572,GTF2H2,IL18,ELK3,WRAP53,BZW2,UQCC2,EID1,HNRNPA2B1,PIK3CG,INSIG2,FASLG,IFT52,CBX7,MIR139,PDCD4,NEO1,STAU1,ETV6,MIR143,MAGOHB,NR2E1,RAN,PIK3R1,MIR24-2,CUL3,NR0B1,SETD4,MIR922,MIR30E,FOXP2,MAGED4B,MIR218-1,TCP1,H2AJ,ELK4,NIBAN2,ISX,CRYM,TRUB1,MIR493,TLR1,MIR137,MIR769,IL15,MIR455,MIR298,MIR194-2,FABP5,MIR532,BCL9,SLC38A2,MIR652,MIR874,CCAR1,SLC45A3,MIR182,ELAVL4,PPP3CA,CLP1,AKT1,DYRK1B,MIR569,IL1B,ZNF787,MTERF2,SLCO3A1,EXOSC8,TLR6,AGR2,MIR595,MIR211,EIF4B,IGF1,MIR604,HMX2,PTRH2,DKC1,ENY2,CNOT2,WTAP,MIR675,GRSF1,CALR,SKIC8,MIR639,TNFAIP3,RBBP4,TXN,GSTP1,MAX,MT3,CREB3L4,MXI1,INPP5E,NEUROD6,TOX,CCND3,MIR631,MIR320A,EIF4A2,MET,MIR1251,KIT,PHF1,TGFBR2,UBE2D1,HNRNPAB,E4F1,TSG101,NR1H2,CDK5RAP3,ZNF343,MIR448,PSMA6,AKT2,COPS2,UHMK1,FOXN2,HMX1,MATR3,PRNP,MIR130B,CARHSP1,SF3B4,MIR589,MIR607,DAPK3,NKX3-2,MIR223,G3BP2,ELF1,FCER1G,ERLIN2,DDX1,MIR379,TRAF3IP2,IL6,EFCAB7,AGPAT1,TOM1L1,PYDC2,CD86,LSM5,PAIP1,SOX21,PLCB1,TLR9,KCNIP3,ORMDL1,TNFRSF1B,MLLT6,ADM2,MIR196B,MIRLET7D,SMG8,E2F6,METTL18,RPL10,MIR580,IFNA2,MEF2B,CDC73,FABP4,DNAJC3,MAD2L2,SSBP3,IKZF2,ZBTB33,MIR204,CLEC6A,ZNF576,MIR423,NMI,FOXS1,GABPB1,UCN,ANXA4,CD80,TAPBP,MED27,GTF2A1,HMGB1,BCL7B,SSBP4,LBX1,RGS2,MIR875,HNRNPH3,GTPBP1,GABPA,HRAS,PYCARD,MIR636,DDRGK1,CRLF3,POLDIP3,NAA15,MIR505,RBBP7,SRSF2,ARMCX3,RAF1,MIR611,IL10,MIR640,FERD3L,STN1,PTGFR,TAGLN3,TRAF1,NKX6-2,RFC5,MSX1,ZSCAN5A,MIR145,CX3CR1,LY96,PRKCA,BRD3,EIF4E2,ACVR1,POMT2,CCR2,F2,PLSCR1,BCL7C,INPPL1,ZNF593,RFC4,USP16,APOBEC3B,NFE2L1,BHLHA9,ZBTB45,TRA2B,CGAS,DAP,ADNP,MIR340,SRSF1,P2RY1,NKAP,FGF22,SIX5,ADORA3,SMG9,TOMM70,MIR590,DNAJC2,POLE3,MIR586,DDIT3,MIR133B,CXCL8,FKBP8,ITGA6,MIR770,UBP1,ATG101,UBE2D3,UFD1,MIR193A,F11R,SLA2,PRKCQ,SESN2,MIR106A,PGR,ZNHIT1,PPARG,EMX1,CCDC22,MIR30A,NR4A2,MIR28,MNAT1,EPO,ZNF664,MIR422A,EGR1,IKBKB,IL34,MKKS,YTHDF2,NCSTN,EIF4H,NFYB,MIRLET7G,CHRNA7,MIR554,EZH2,UPF3B,GCLC,WASL,DYRK1A,ZNF177,KLK3,MIR152,PROX1,CREBBP,TNFSF18,MIR147B,ZBTB18,KRAS,DPY30,IL1A,PPP1R3C,FGF10,TF,IRF6,IL2RG,NCK1,MIR656,TRIM22,MTF1,AIP,PYM1,LITAF,PICALM,MIR200C,CCT2,MIR425,SMAD1,IRF7,NLRP6,MIR1260B,ZSCAN1,ACTN4,ZBTB26,XPO5,FOSL2,LTA,COPS5,CDCA7L,SUMO1,HNRNPC,OAS1,DIRAS3,TWIST2,SETD3,MIR105-2,PDCD5,APOBEC3D,DDT,ATP6AP2,SNIP1,CDK1,OSR2,MIR194-1,RPS6KA4,MIR557,EED,MED21,NFIL3,TNFSF8,CTDSP2,CASK,MIR106B,ITM2A,GPSM3,FITM2,DLX1,LRRC14,SSBP2,MYC,MIR184,MIR126,MIR553,DAPK1,HSPB1,MIR490,MIR142,MARS1,RBM22,IRF9,ZNF397,SMAD2,MIR342,ALKBH5,SLC38A3,BRCA1,BUD31,MIR31,APOBEC3F,UBE2I,ZNF687,SNRNP70,ZHX1,MIR324,CD4,TNKS2,PSEN1,PPP1CB,MEPCE,RBBP8,CAV1,IFNB1,RBFOX2,TNKS,MTG1,MEAF6,PIM2,RAB1A,SUPT7L,MIR23B,CLU,MACROH2A2,OTULIN,MED30,NKX3-1,NFKBIL1,PKNOX1,RPS7,PCBD1,NR2F6,MAGEB10,CRTC2,TUSC2,SERPINB1,PNRC1,MIR920,ELOC,TFRC,NEK2,CD38,CD2AP,FXR2,GADD45A,NDP,FKTN,ZBTB25,SFTPD,TLR5,H2AZ2,BMPR1B,TFCP2,HCLS1,PML,EIF2S1,MIR141,MIR491,SNAI3,TERT,PABPC1,MIR765,EIF1B,SMARCA5,PIWIL3,ZNF740,MIR148B,TCOF1,PHB2,ZNF175,MIR601,CD200,COMMD6,POLR2G,SQSTM1,LEP,MIR34B,MIR873,MIR7-3,MED17,STK16,HOXB8,MIR625,GTF2IRD1,MIR100,TRIM3,BRMS1,ZNF319,NTRK3,MIR296,TLR8,MYT1L,CIPC,MIR563,MIR618,CCDC3,EIF3K,RFXANK,MIR153-1,EIF4EBP3,EIF2B5,MPV17L2,PRMT6,SOX3,DNAJB4,NFE2L2,BMPR1A,SMARCB1,DRAP1,MIR549A,SEMA7A,TFE3,SRSF4,UBE2V1,EID2B,MIR1271,MIR578,NOP53,MIR938,LSM4,RNF128,SMAD4,INO80E,SNX5,DR1,MIR384,PDCD10,MAGOH,EIF3D,NAA16,KARS1,CTNNB1,SP2,MIR1227,HYAL2,SHLD1,KLK5,H2AC7,TSNAX,GPT,TNFSF13,MIR377,CREBZF,RIOK2,GRIA1,LMO4,CD14,EIF2AK2,RLN2,SS18,MIR221,MIR155,PSMC3,CARTPT,UBE2N,SLC8A1,RRN3,MIR497,NCOA5,MORF4L1,MED31,FBXL19,MIR500A,PTEN,JAK2,MCPH1,LMO2,USP3,CAND1,STAT1,LRP6,DVL2,LACC1,CRY1,DEFB114,SMCHD1,CD34,ABCE1,RAB27A,MIR186,OTX2,JUNB,PRL,TRIM34,HAS3,LDLR,ENO1,DMAP1,MIR10A,NEUROD2,ZNF263,PELI1,PPARA,RXRG,IFNGR1,THRAP3,LDB2,RNASEL,FGR,ERP29,GTF2F1,CSK,RFX5,MIR633,BTG1,ZNF267,DNM2,MIR330,SYNCRIP,NGDN,CREBL2,CPNE1,ELP6,WDR82,ANAPC2,MIR21,ECD,CKS2,PC,MED29,IFI27,BAP1,RBBP9,MIR129-1,CD36,SRSF10,FOXD3,IREB2,TCF21,DXO,FGF7,PLAC8,MIR615,HEXIM2,CDK5,MIR98,KDM2A,MIR649,PKIA,CCT8,GTF2A2,MIR628,MIR1298,CX3CL1,NGRN,ANKRA2,MUL1,FCGR2A,MIR624,MID1IP1,PHB1,ING1,ZHX3,PPM1D,ZBED4,MIR502,MIR214,H2AB1,NLRP3,CASC3,CLDN3,H1-5,IRF4,FUT8,PDCD1LG2,MIR552,SUPT5H,TENT5C,TOP1,LSM14A,MED4,MIR105-1,CDKN1A,MDFI,MIR16-2,EID2,RPL6,TMEM107,ILK,ZNF655,MIR301A,NLRP2,ZNHIT3,ZNF473,INTS10,BAG2,CSRNP3,HSPA8,MIR147A,PAX9,JADE1,ZNF790,CER1,SDCBP,HENMT1,MDM2,MIR188,TP53,MIR583,MIR1-1,NCBP2,DDX5,TRA2A,CDKN1B,TRIM52,MIR193B,MIR218-2,HOMER3,FOXJ3,RBM15B,UFL1,RBM3,ZNF692,MIR335,KPNA2,CYP27B1,ZNF189,ZBTB14,TRIM15,MIR195,ZNF526,FAF1,PIWIL1,ZNF326,MIR198,MIR1249,DROSHA,HEXB,RFC2,MIR600,DKK1,HOXB1,MIR367,GLRX2,RNF8,STAT6,CCR7,HAND2,PRDM4,MBD3,LCORL,SRSF7,DDX4,ADRB2,PARM1,PLD3,MAP2K3,MIR192,LRP3,RERE,ZNF596,OTUD7B,RPRD1B,MIR9-1,LSM2,SCAND1,HOXC4,DHRS7B,PAEP,GHRL,CPEB1,CSNK2A1,HNRNPA0,SOX9,NDFIP1,SART3,MIR489,SNAI2,ZNF7,DCAF5,RBM23,CD200R1,EIF4EBP2,CDC5L,MIR339,PPTC7,NR1I2,PRPF19,TRIM29,PELO,ING5,SAP30L,CCR1,IRF8,NUCKS1,MIR558,MIF,HNF1B,MIR132,BCL10,IL12A,EIF5A2,RWDD3,HEY2,IRF3,MAP3K12,SETD7,STK3,MIR1225,KLF12,ZNF518B,RORB,CCL5,DMTF1,RPS14,TLR3,TRIM68,DYRK2,AKAP12,MIR3173,MIR761,MIR484,ZNF652,FLCN,MIR302B,NUPR1,SECISBP2L,AGO1,CRYAB,THAP1,MDC1,MIR504,IL4,ILF2,MIR662,FAM98A,SCML1,MIR146A,DGCR8,NKRF,GPBP1L1,CHID1,MIR101-2,CPTP,MIR452,TADA1,SPIN3,LANCL2,MIR150,ING2,DKK3,RUVBL2,HILPDA,PITHD1,SYK,FGF16,NLRP1,HNRNPL,BOLL,PRDX6,FBXW7,PRR5L,EAF2,TESC,S100A8,NOG,EWSR1,APOBEC3C,MALSU1,TRIM5,SELENOT,MIR129-2,MIR363,APBB3,VSIR,MIR101-1,TRIM32,TRMT112,UBE2L3,GPAM,MED9,MAGEA4,ZSCAN25,MED23,LAMP3,SERTAD1,CNOT6L,RASD1,C1D,APOBEC3A,H2AC1,MIR373,TACO1,ZNF287,VAMP3,PIAS1,TBK1,CYRIB,XRCC5,CDK4,MIR632,MIR32,ZBTB39,NPPC,IGF2BP1,PSMC5,CLEC9A,CCL2,CHCHD2,RBM42,ARL2BP,EIF5B,POU1F1,DNAJC1,PDE2A,CIART,SERTAD3,H1-3,RB1CC1,KLF3,CCDC85B,CD58,TFEB,MIR140,PDE4B,MIR939,CD40LG,TAF1D,IL17F,TAF10,PIK3CA,CD47,ZC4H2,APEX1,ROCK1,SUPT4H1,PHAX,MIR15A,MIR944,KLF1,PIK3R2,MIR301B,PRKACB,OSM,CCL1,YWHAZ,SOX14,DEK,KRBOX4,FZD4,CAPN2,CAMK1,NSMCE3,NUDT16,MTPN,EIF3E,FGF23,PPM1B,IL23A,CLK1,MTA2,VEGFA,SATB1,ZNF704,CEBPE,MIR374A,VSTM2A,WNT7A,TGFB3,SIAH2,DUSP26,ACO1,RPS4X,FUBP3,RPL26,CCT7,SERTAD2,ITGA2,SAP30,NFKBIA,CLK4,PPP1R11,BRD9,MIR331,TCF23,SIRT7,BAK1,VDR,TEF,ZNF688,MIR345,MIR877,RPL13A,XBP1,MED13L,PID1,TSC22D3,CCND1,HIRA,PAIP2,CYTL1,MIR130A,IL2,MIRLET7B,SOD1,AR,MIR492,TCEAL1,PHC1,TAF11,MIR125A,FGF1,ACP5,MIR187,GNB3,MIR450B,RGMA,SMU1,MIR10B,ATF1,DIO2,PPP2CB,PPP1R12A,ACTL6A,FOXP3,CD274,MIR1224,HAX1,E2F4,LMNB1,SMARCE1,TENT4A,KLHL25,MACIR,GNRH1,MAGEC2,ZNF513,MMP14,TP53INP1,ZNF581,ZBTB2,EIF4E,ID4,BAHD1,PTP4A3,PADI2,CHMP1A,IFNK,SMARCD3,HDAC3,MIR148A,ZNF24,ZBTB16,MIR383,NACC2,SFN,DNAJB6,MIR96,ZNF507,MIR648,SMYD3,GFPT1,RIGI,PAX6,MIR577,WNT10B,TXNIP,MIR887,TP53INP2,PRKAG1,MIR454,MIR495,YTHDF1,CXXC5,ZNF770,INO80C,EPHA2,LARP4B,S100A10,AGER,MIR361,ZNF304,MIR23A,BATF,ADIPOQ,FGF17,LBH,H2AZ1,MIR567,YAF2,ROCK2,NMBR,CBX5,TRAF2,ETF1,FOXP4,RPS3,EEF2,TRIM6,MTRES1,DIS3L,TFDP2,XAF1,LDB1,CGGBP1,MIRLET7C,MIR657,RHOH,MIR581,ACOT8,MIR1277,PSMD10,TNFRSF14,CXCL10,JPH4,SPHK2,H2AX,SPINDOC,FBXW11,RAG1,MIR424,OGG1,ATXN1L,FGFR1,HELT,PIWIL4,ACSS2,MIR155HG,VGLL2,SCAMP5,ENC1,CKS1B,HUWE1,PTPN11,HDAC11,NONO,CDK6,TFPT,FOXI3,TRIM27,TAF7,IDO1,TENT5D,ZNF451,VPS72,MITF,MIR216A,CLEC7A,IL21,MIR34A,IL13,MIR609,ZNF671,RNF20,TSPO,ZBTB6,BTG2,DCP2,JUP,GPNMB,MIR711,RNF187,CYP7A1,MIDEAS,SP1,CCNA2,PTGER4,MIR626,SFRP4,RPL23,RAD21,POLR2L,LSM6,SLC6A4,GAPDH,MIR934,TGFB1I1,MYRF,CNOT7,FZD6,ESR2,MIR1262,ITK,IL7,RFXAP,EZH1,IER2,TRIM37,IRF2,USP13,SOX2,PTPN22,PDE8A,NFKBIB,ABHD14B,PXYLP1,HSBP1,CCNQ,CDH13,PIWIL2,MTDH,ADTRP,MIR940,GREM1,NOTCH2,RBM7,SRPK2,SVIP,RASL11A,CRIP1,ACTA2,HNRNPH2,CHP1,TGFB2,CRYBA1,METAP1,PAK6,MIR144,MIR612,RING1,PCNA,ZBTB38,MXD1,HBP1,CCL21,MIR20A,TADA3,NFE2,CIRBP,BAZ1B,ATP1B1,CDK7,MAFG,ATP2B4,RIT2,MACROH2A1,MIR708,ZC3H14,ZNF174,PAGR1,CTBP1,PRKCB,SHC1,ZNF250,TRAF3IP3,SASH3,PSRC1,CD83,MIR190B,HTR2A,INPP5K,GATAD1,APLN,MOV10,KLF9,SAP30BP,SMAD5,TGIF2,HSP90AA1,CDK5R1,H2AC13,MAGED2,KDM4B,SPON1,G3BP1,THOC2,GLO1,WWP2,HNRNPA1,MIR216B,CREB1,FRMD8,MIR556,PRDX3,TDRD7,APOBEC3G,MIR208A,IFIH1,PKIG,ZMYM2,RUNX1,ZMPSTE24,GFI1,TAF2,WWP1,ZGLP1,HBEGF,TRIM26,ZBTB42,AP2A1,EGR2,LILRB4,RPS27L,ARB2A,SP4,TRIM11,SMG5,RC3H2,VGLL4,ERLIN1,HSP90AB1,CBFB,TAX1BP1,CD28,BEND5,MEF2C,ZCCHC17,MSTN,MIR205,SETD5,MIR599,MIR924,KLF10,PCGF3,ATF3,ZNF32,FCGR2B,ELP3,MIR653,STAP1,ELF5,SLC7A11,SCML2,MIR24-1,SMAD3,CSRNP1,DUSP22,HNRNPD,WNT2,CCN3,TAF9,KMT5B,EIF4A3,TRIM62,IRF2BP1,TMIGD3,SELENOK,MIR181D,NUDT12,MIR1180,MIR802,POU3F4,TRAF6,HP1BP3,TICAM2,MIR222,CCL19,HOXD12,TRIB1,MIR378A,PLAGL1,RNF40,PRSS37,IRF2BPL,FOS,CHI3L1,PSPC1,HNRNPF,RPAP2,ARG2,NFKB1,LRIF1,ZKSCAN1,PLP1,SUPT3H,MIR937,HLF,PTGES3,SRGN,NRDE2,MIR34C,CDK20,SRC,PPID,ZNF609,ANGPT1,HEXIM1,TRIM21,NOVA1,ATF4,ZNF22,HNRNPK,TENT2,BIRC5,ZBTB5,IFNG,PRKRA,MEF2A,MIR135B,LGR4,PQBP1,ITM2B,IRF1,AFAP1L2,UTP15,INSM2,IFI16,STARD4,NTRK2,LMO3,MIR551A,CCT5,CTNNBIP1,TCEAL7,METTL14,ACTR2,SMAD9,TICAM1,MIR181C,MIRLET7I,MECP2,BMPR2,TAL2,EDC3,MIR29A,EXOSC3,CELF6,MIR542,MOG,LMNA,ZMYND11,ZNF862,GMNN,AKAP17A,MIR136,PRMT5,MIR99A,MIR92B,H2AC6,MIR9-3,DRD3,TANK,SELENOS,EP300,RFC3,PIK3R3,WDR77,OVOL1,BACH1,LSM14B,TMEM106A,ANXA7,GPX1,AATF,SNX12,ODAM,MIR206,MLLT11,MIR643,H2AC4,CTDSP1,PHF21A,CDK12,TRIM24,MSN,CRKL,MAF1,BST2,MIR573,PKIB,TIRAP,RAMP3,KPNA6,GSK3A,DEDD,JUN,PNP,MORC2,HSPD1,CBX3,MIR885,MTA3,MIR449A,ZFP1,FLOT1,EMX2,CXXC1,FOXP1,MIR190A,STOML2,MIR185,DUOXA2,POLR3B,PCBP4,UBE3A,IL12B,RNF14,USP2,MIR1-2,RSAD2,BGLAP,MIR107,ZFP64,MIR651,ABCC2,MIR548C,POGK,ILDR1,ZNF280B,MYBL2,RGCC,TIA1,MIR375,LILRA2,MSX2,MTG2,MIR30B,INHA,MIR519D,RBFOX3,ELK1,LYAR,SIN3A,EIF4E3,MIR210,POLR3F,MIR593,MIR33B,RMND1,ZNF592,MIR197,H3C1,POU5F1 |
| 3.629e-07 | -14.83 | inner mitochondrial membrane protein complex | cellular component | GO:0098800 | 148 | 72 | 19108 | 5553 |
ATP5MG,NDUFAB1,ATP5MC3,TIMM23,COX7A1,SMDT1,SDHB,NDUFS3,COX6B1,NDUFA4,NDUFS2,PHB2,ATP5F1B,NDUFS6,SAMM50,PHB1,TIMM21,SDHC,ATP5PB,NDUFS8,NDUFC2,MTX2,NDUFA1,TIMM10,NDUFB10,ATP5PF,UQCC3,GRPEL1,UQCR11,CYC1,NDUFV2,NDUFB4,NDUFA5,COX4I1,COX7B,BCS1L,ATP5PO,NDUFB8,CHCHD6,UQCRC2,NDUFB6,COX6A2,COX8A,ATP5F1E,ATP5F1D,NDUFB5,APOO,GRPEL2,TIMM17A,ATP5F1A,UQCRC1,MPC1,AGK,NDUFA2,UQCRH,PDSS2,COX5A,ATP5PD,NDUFB7,ROMO1,COX6C,ATP5MC1,DNAJC19,PPIF,TRMT10B,UQCRQ,COX4I2,IMMP2L,TIMM29,CHCHD3,NDUFA12,ATP5MK |
| 3.651e-07 | -14.82 | small molecule metabolic process | biological process | GO:0044281 | 1614 | 564 | 18204 | 5365 |
UGP2,NPPC,CLPX,PDE2A,HPGDS,NUDT9,UCK1,CBR4,SLC25A44,CYP2C9,CACNB4,RDH10,THTPA,NDUFB5,EXTL2,FUT9,ARG2,ATP5F1D,ALOX5AP,MGAT4A,PLP1,HSD17B3,LIPT2,TPST1,FMO3,CD38,GSTM4,APOBEC3A,NUDT12,NDP,CYP1B1,ENTPD4,TLR2,G6PD,URAD,PTHLH,STAT5A,UMPS,ACAT1,BPGM,MECR,MMAA,SLC2A1,LHB,SARM1,PCBD1,MCAT,ERH,NT5C2,UCKL1,CRTC2,GLUL,GPAM,SLC23A2,FA2H,STAR,EGLN3,NPC2,PRKAB1,PPAT,GK2,CH25H,SYK,NPY1R,SDS,MSMO1,NDUFA5,DPM2,HSD17B6,AKR1B1,NME2,ATF3,ADIPOR1,GFUS,APOBEC3C,HNMT,SNX17,AKR1C1,NDUFB4,ABHD2,AKR1C2,PTS,RRM1,ETFB,FABP5,HACD1,AKR7A2,ALPL,MECP2,NUDT16,SFXN1,FGF23,CYP4V2,HMGCS1,SLC38A1,MGST3,SMUG1,CMPK1,LYPLA1,SAMHD1,PPM1K,VKORC1L1,CA12,RAN,FAH,GSTO1,NDUFS6,SLC25A32,ASNSD1,AK5,DDAH2,SLC52A3,ELOVL4,PGK1,NDUFB8,MGAT1,CRYM,ATP5PB,PIK3CA,NUDT4,PAFAH1B1,ELOVL3,NMRK1,MACROD1,SERINC3,GMPS,ADK,NDUFS2,OARD1,LYPLA2,PGM1,DBT,CYP39A1,GNPAT,DECR2,DLST,SLC25A21,NDUFB10,NME1,PTGES3,CHST1,PDSS2,KCNJ11,MMADHC,NT5C3A,ACO2,ATP5MC3,ADH1B,COX11,AIG1,RETSAT,ABCG2,UGT2A3,INSIG2,IDH2,HSD17B8,LEP,PDE4B,FAHD1,ATF4,PCSK9,PLA2G5,B4GALT1,VLDLR,ADCY2,EGLN2,CRY1,ACER3,SCPEP1,SPTSSA,SLC25A10,AKR1A1,ATP5MC1,ACACA,DCK,BAD,COQ8A,DOLK,EHHADH,PNPO,XBP1,MMACHC,TP53I3,PLAA,GDPGP1,GAMT,CYP2C8,RPE,UQCC3,UCP2,CYB5R3,IGF1,HSD17B10,NPC1L1,COQ10B,GK5,KARS1,ASPA,TTR,CRYL1,NPR2,GSTP1,CYP2R1,CRTAP,ATP5PD,GPX1,PRPS1,GPT,BRS3,KBTBD2,ESD,AKT1,PYCR2,CA10,PCCB,HACD4,ACO1,LBR,FKRP,PFKFB2,REXO2,ADCY3,GMDS,GFPT1,ADSS2,PC,ELOVL7,PHYH,SLC25A42,DCAKD,ENTPD3,PNPLA8,CD36,ASRGL1,NUDT19,PRKAG1,NDUFS3,IREB2,NUS1,PCK2,PLCB1,OGDHL,MFN1,MTAP,HACD3,GUK1,TKTL1,PRPSAP1,MGST2,OCRL,MDH1,SLC35A2,RIMKLB,DHRS4,HADH,ETFA,SRD5A3,CYP27A1,STOML2,ACSL4,FBP2,RAB23,ERLIN2,SUCLG2,IDH3A,ABHD6,AHCYL1,ENPP4,NDUFB6,NANP,HEXA,SEPHS2,ADIPOR2,DEGS1,CRMP1,ACAA2,PNP,MAT2B,MORC2,AKT2,ERRFI1,VDAC1,FUT1,ENO1,CA2,LDLR,SLC37A4,DLAT,GNMT,IMPA2,SULT1B1,GNPNAT1,UCK2,SLC1A3,PPARA,UPRT,GPD2,INPPL1,FOLR1,DCTD,SDR16C5,APOBEC3B,SPHK2,LRAT,MPST,ELOVL6,GUCY1B1,NFE2L1,ELOVL1,FDFT1,OGG1,NUDT3,ECHDC1,TYMS,CYP11B1,SLC22A12,GGT7,ANKH,MTHFS,PDHA1,CFTR,AZIN2,CA14,FUT8,AMT,ALDH1A3,SDHB,HSD17B1,ACOT8,GGCX,ADIPOQ,CYP17A1,TNF,PLAAT3,SHMT1,CYP11B2,PPT1,RDH12,DBH,DDAH1,CYP4F12,CYP3A5,MME,BCKDK,RDH11,EPHA2,ABHD5,GTPBP1,FBP1,ATP5MK,DPAGT1,PYCARD,PTGDS,GNPDA2,HINT1,CLN8,CBR3,CYP27B1,GAPDH,PNPLA4,SLC25A11,CYP2C18,PYCR1,HEXB,FAR2,AK3,ATP5F1E,AASDHPPT,PDE9A,SDHC,CDO1,GSTO2,KDSR,GNPDA1,NQO1,ALG2,SLC25A12,SESN2,ADH1A,GSTA1,PPARG,CYP7A1,NSDHL,LIPA,ACOX1,SLC16A1,APOBEC3H,SC5D,GMPPB,PAPSS2,NUDT7,ACCS,FADS2,UBIAD1,ST6GAL1,TP53,HADHA,IDO1,GNAI3,PEDS1,NDUFV2,CYGB,ACBD7,CSGALNACT1,CNP,LEPR,FHIT,UGT1A1,CRABP2,COMT,NDUFAB1,MTHFD2L,FGFR1,GGTA1,HSPA8,SCD5,ACSS2,GHR,INPP4A,PIP4P1,IP6K1,SPTSSB,MPP1,DHRS3,ENO2,UGDH,SORD,RIMKLA,KDM1A,KGD4,ILVBL,DNPH1,GAD2,LDHAL6B,PRKCB,SLC19A3,OAS1,IDH1,GHRL,RGN,DHRS7B,GPX4,AZIN1,MTARC2,ATP5PF,TECR,TST,ATP1B1,MVD,DLG1,NDUFA2,ATP1A2,GLRX,CYP1A1,P4HA2,PDE1A,RPIA,DPEP1,OSBP,ATP5MG,FPGT,DHRS7,ATP5F1B,SLC2A3,ACADS,CPT1B,LIAS,CPT2,NUDT2,GDPD3,PDE8A,NDUFA1,CA8,PGM2L1,GCLC,LDHA,SLC5A6,PEX13,OLA1,PLA2G15,QNG1,ABHD14B,PGAM1,GSTM2,FMO1,SEPHS1,AMACR,MAT2A,MPDU1,RBP2,PDHB,UAP1,ADTRP,SULT1A3,ATP6V1A,GALE,COQ8B,MOXD1,CRAT,AK2,DCTPP1,NME4,ODC1,LDHB,CMAS,ERLIN1,ACOT6,IDH3B,SLC25A17,OXCT1,ST3GAL1,CYP2D6,NUDT5,IL4,BRCA1,ABHD12,NDUFC2,SLC6A8,ATP5PO,APOBEC3F,EPHX1,NUDT1,DTYMK,CYP4F22,SLC19A2,PLPP6,SPR,FITM2,DNAJC30,FMO2,TPH2,CASK,CYP4F8,MMUT,NUDT18,HACD2,GLO1,IER3,ALDH1L1,PTGES,G6PC3,APOBEC3G,SLC25A1,AUH,ABHD10,PLA2G4B,ATP5F1A,APOBEC3D,MIF,ISYNA1,NDUFS8,CYP26A1,MBLAC2,PMM2,HTR2A,OAT,NDUFB7,UST,ACADSB,NDUFA12,PDE7A,GLYAT,GDE1,CYP2F1 |
| 3.843e-07 | -14.77 | TPD52L2 (TPD52 like 2) | protein interactions | 7165 | 150 | 71 | 19454 | 5460 |
PPP2R5E,PSMD4,GABPA,MYC,RAB2A,RAB11A,DRAP1,DNAJC5,LAMTOR1,NIF3L1,RHOB,BICD2,PFDN2,OSGEP,CALU,BAP1,PPM1G,INPPL1,RPA3,PML,RAB9A,ARPC2,PMAIP1,RAB5A,GTF2I,PAFAH1B2,GPC1,STAU1,STX7,PIP4P1,CDC42,CDK7,ABHD5,VAV2,RPA2,TPD52L1,RAB35,HRAS,COQ8A,ARF6,PRNP,DIRAS3,LMAN1,CALR,LAMP2,ATG9A,MOV10,RAB5C,COPS5,LAMP3,BTF3L4,RHOG,THG1L,COX8A,HSD17B10,PDIA6,KRAS,TRIM26,RAB3B,PTGES3,AHCYL1,SAR1B,ANP32A,RAF1,TPD52,TXNRD1,EZH2,GABPB1,RAB4A,ACTR2,SH3GLB1 |
| 3.849e-07 | -14.77 | PIAS2 (protein inhibitor of activated STAT 2) | protein interactions | 9063 | 169 | 78 | 19454 | 5460 |
ZNF319,PML,DDX39B,RPA3,HDAC3,GTF2I,PIAS1,TICAM2,COIL,SUMO1,CDKN1A,MX1,GTF2IRD1,SNAI2,CTBP1,LMNA,RPA2,KLF3,PAX9,ELK3,ZNF330,CREB1,UBASH3B,UBE2I,ZMYM2,TRIM27,PRKRA,SIAH1,SPINDOC,PLAGL1,DES,ESR2,GRM8,UBE2L3,HOMER1,MYC,CREBBP,AKT1,AR,TRIM23,LMNB1,CCHCR1,GLUL,ZNF451,SNIP1,PCNA,TRIM63,ZBED1,HUWE1,ZBTB16,SYN3,SMN1,MX2,TP53,EXOSC8,MSX2,JUN,TRAF2,PHC1,ETV6,SMAD3,TSR2,SEC23A,SUMO3,SUMO2,PRNP,MITF,PGR,HMG20A,CGGBP1,FAM118B,PPIA,ELK1,IFIH1,SIAH2,EDC3,YWHAH,SMAD4 |
| 3.878e-07 | -14.76 | KASH5 (KASH domain containing 5) | protein interactions | 147872 | 113 | 57 | 19454 | 5460 |
FIS1,CDC73,NTAQ1,TTC23,SLC35B4,TMEM41A,ZNF250,EFNA5,ESR2,CYBC1,SGTA,SMCO4,LMNA,MMP14,RNF146,PLP2,VAMP1,CTXN3,GABARAPL2,FAM161A,PGRMC1,GOSR2,MTX2,BET1,KDM1A,DERL1,CLDN8,JAGN1,ITM2B,FAM50B,TMEM11,FAM241B,FATE1,SLC41A1,TMEM199,FRA10AC1,TMEM19,CIB3,ANKRD46,PPP1R18,VTI1B,CXCL9,MFSD5,STX5,TRAF3IP3,STX12,VAMP2,CRABP2,STBD1,PGAP2,PLPP6,GALNT2,TNF,NSG1,ADIPOQ,DNAJC30,TMEM147 |
| 3.878e-07 | -14.76 | HCCS (holocytochrome c synthase) | protein interactions | 3052 | 113 | 57 | 19454 | 5460 |
RDH11,COA4,NSDHL,SFXN1,NDUFA4,FAM136A,MGARP,APOO,DCAKD,LYPLA1,PHF23,SNX20,MTCH2,WIF1,COX14,SLC25A12,PLGRKT,FZR1,TXNRD3,AGK,SNX1,AIFM1,COMT,COX4I1,ESYT1,CIDEB,LAMTOR2,CERS6,MRPL17,PHB2,GRPR,SLC25A51,COX17,RMND5B,PEBP1,PIH1D1,CYC1,ACACA,ARMCX3,CDC42,TIMM29,TIMMDC1,VIRMA,PARL,RAB14,CPT2,TXNDC12,TAX1BP1,TNFRSF9,RRAS2,OPTN,MID1IP1,CYB5R3,TYROBP,TADA1,RAB2A,KCNQ5 |
| 3.878e-07 | -14.76 | BMI1 (BMI1 proto-oncogene, polycomb ring finger) | protein interactions | 648 | 650 | 240 | 19454 | 5460 |
ATF1,CAPG,PYCR1,CUL3,CFAP20,LSM14B,AP2M1,EIF3K,RSRC1,PRRC2A,ERH,DYNLL1,TUBB,CDKN1A,ACTL6A,SLC25A3,LARP4B,ADNP,FOXS1,G3BP2,SKP1,CSRP1,YTHDF1,PTN,EIF3D,TRA2A,HNRNPD,CDKN1B,DROSHA,WDR12,DDX23,HP1BP3,RPLP1,KRT8,MRTO4,PSMB5,MYEF2,CBFB,ZNF593,RPL7,BUD31,KCTD10,AGK,NOP58,RPL29,SART3,AP2S1,NME1,EZH2,RPN1,RPS24,BAG2,UBE3A,SRSF7,SLC39A7,ZC3H7A,NDUFA4,ARGLU1,MRFAP1L1,TRIP4,SLC25A5,PCGF6,PPWD1,SRSF4,CBX7,TRIM37,DHX16,PCGF3,G3BP1,ZBTB16,TUFM,AR,RPL26,ZNF687,CASC3,AP2A1,CCHCR1,UBE2I,PTEN,RPS20,RTRAF,PRKRA,TRIM27,FBLN5,EIF4A3,TUBA1B,VIRMA,DEK,SCML2,RPL13A,EIF3J,RBFOX2,RPLP0,LMNA,RPA3,NHP2,DGCR8,APOBEC3F,SPATS2L,MOV10,ESYT1,KRR1,EIF4E2,AIFM1,SRP14,HACD3,G6PD,NCBP2,LBR,MRPL11,YTHDF2,TRAPPC13,ILF2,IGF1R,RING1,ZC3H11A,ZNF787,NKRF,SFXN1,TFPT,RAB1A,SLC25A10,SMN1,PRDX4,EIF3E,CTNND1,TUSC3,ARF4,SOCS2,THRAP3,SNRPB,SFN,CDKN3,HNRNPAB,HNRNPC,PRMT6,CREBBP,H1-1,FTSJ3,H1-10,CHTOP,CCT2,CIRBP,SMU1,RPL10,LRIF1,CBX5,ATP5F1B,DUSP14,NCOA5,NUFIP2,MAP2K1,PCGF2,EP300,YAF2,XRCC5,CCDC9B,DDX39B,SAP18,STAU1,UBE2D3,FXR2,HNRNPA0,PPIB,IFI16,BAZ1B,MAGOH,CBL,EED,FUBP3,RAB35,PGR,ZNF740,PAIP1,RPS10,SOX2,UBL5,PNMA2,TUBB4B,RTCB,RUVBL2,EWSR1,CCT8,LSM14A,HNRNPF,TIA1,SUGP1,SMARCA5,IGF2BP1,ELAVL2,SPOP,EIF3G,MACROH2A1,CSNK2B,PSPC1,RPS3,SRPK2,EIF4H,AGO1,SPTBN1,ACACA,LUC7L3,E2F6,TFIP11,ZNF326,RPA2,TWNK,MAPKAPK3,NBN,BANF1,RBM22,NME4,KDM1A,CSNK2A1,USP15,AKAP8L,H2AC4,ALYREF,EEF1B2,DKC1,TMPO,KCTD3,CAND1,H2AX,WBP11,TP53,IL1R2,STRBP,RRM1,PHC1,SFTPC,IK,NFE2L2,CBX3,SLC25A11,PALM2AKAP2,MEPCE,KPNA2,SCML1,H3C1 |
| 3.883e-07 | -14.76 | UBA2 (ubiquitin like modifier activating enzyme 2) | protein interactions | 10054 | 236 | 102 | 19454 | 5460 |
LIAS,SUMO1,RPA2,TTI2,SEPHS2,BAP1,SNCG,RPA3,PRIM2,DERL1,KDM1A,BRIX1,CARS1,XPOT,CDC73,PTTG1,CALU,UBE2H,STUB1,CCNF,UBE2I,COPE,NDN,CHMP5,PPAT,DYNLT3,NDUFA2,CBX3,UBE2B,RAD23B,FURIN,TAF2,EHD4,HAPSTR1,HSD17B10,REXO2,PSMA5,CTNNBL1,PDE12,NEDD8,RBCK1,CTSC,CENPP,RBM17,COPS5,GTF2E1,SRP14,GNPAT,CEBPG,EIF2B5,CAV1,ACTL6A,PGRMC1,PSMB3,PAFAH1B1,EDEM3,TOM1L2,NEK7,MFAP1,RFC4,LCA5,PSMA3,SRSF2,ATP6V1G1,MYC,PSMA4,CUL3,PSMD1,MCM3,SNRPB,BAG3,RBBP8,SRXN1,ZNHIT6,PRMT5,IREB2,CLIC4,USP5,MED9,STMN2,ARGLU1,SDHC,UBE3A,PSMA1,KRAS,PSMA2,RPS27A,AHCYL1,SAR1B,WDR11,ZCCHC9,HSPB1,RPL8,PSMB4,TTC9C,NOP58,ZNF511,ATXN10,SNRPD3,SUMO3,SUMO2,CHMP2A |
| 3.883e-07 | -14.76 | CTSL (cathepsin L) | protein interactions | 1514 | 236 | 102 | 19454 | 5460 |
RNF5,EMC1,YTHDF1,GNB4,SNRPA,ATPAF2,DDX39B,XRCC5,TMEM106B,HADHA,ATP5PO,TOMM22,EFHD1,PGRMC1,TIMM13,CBX5,CLIC4,VDAC2,DLST,MCPH1,SLPI,MYO6,CTSK,SERPINH1,FMC1,CUL2,RAB11A,MLF2,VDAC1,FKBP2,RAB18,SSRP1,POLDIP3,NDUFA4,MYO1B,BAG2,ERP29,RPN1,PLD3,ACTN4,FAF2,ERLIN2,SPTAN1,NUP35,LANCL1,THOC2,PHB1,EED,XPO5,SPINT2,CSTA,PDIA3,CST3,PDHB,GTF2I,CLU,MARS1,RPA3,BANF1,CSTB,ITM2B,ARPC2,DLAT,RPA2,HSP90B1,RARS1,EEF1E1,CXCL8,IGFBP3,NTPCR,TXNDC12,STUB1,PELP1,CDIPT,GANAB,SGTA,ALB,CALU,RSPH1,PPP1CC,TUFM,HUWE1,CTSC,RIGI,MDC1,PRDX4,SLC25A11,ZC3H11A,TFRC,ARPC3,ADAMTS1,GNAI3,YTHDF2,MRPL11,TP53,LMAN1,SSBP1,AKAP8L,CALR,MOV10,KARS1,GLO1 |
| 3.952e-07 | -14.74 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | REACTOME pathways | R-HSA-8854050 | 56 | 36 | 10285 | 3229 |
PSMA5,PSMB10,PSMB11,PSMC5,PSMA4,PSMA6,PSMB3,PSMD1,PSMB2,PSMB6,PSMA2,PSMB1,PSMB7,PSMD3,PSMC4,PSMC1,PSMD12,PSMA3,PSMB5,PSMA1,PSMC3,PSMD14,PSMD4,UBB,RPS27A,UBA52,PSME1,PSMB4,PSMD6,SKP1,PSME2,PSMD10,FBXL7,PSMD7,SEM1,PSMB9 |
| 3.978e-07 | -14.74 | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 | gene3d domains | 3.60.20.10 | 24 | 19 | 14470 | 4137 |
PSMB2,PSMA5,PSMB1,PSMB10,PPAT,PSMB9,GFPT1,PSMB3,PSMA6,PSMB4,PSMA3,ASNSD1,PSMB6,PSMA1,PSMA4,PSMB11,PSMA2,PSMB5,PSMB7 |
| 4.011e-07 | -14.73 | GTF2H2C (GTF2H2 family member C) | protein interactions | 728340 | 45 | 29 | 19454 | 5460 |
HNRNPL,IL18,GGPS1,UBA3,CLK4,FAM43A,DYNLRB2,CDC7,GTF2F1,GTF2H2,RIT1,BRD3,MYC,ERCC3,CUL3,NTAQ1,XPO1,AR,KRAS,FBXW7,STAU1,IRAK4,EXOC3,GTF2H5,ILF2,GTF2H4,HEXA,PRMT2,CDK7 |
| 4.038e-07 | -14.72 | regulation of transferase activity | biological process | GO:0051338 | 645 | 248 | 18204 | 5365 |
MAP2K1,GSK3A,HGS,CDK5RAP3,DVL2,DIRAS3,DEFB114,BAD,FCGR1A,JAK2,PTEN,TSG101,MMD,MAD2L1,CCT2,MACROH2A1,LRP6,FGF1,PKIB,PAK2,SKP1,TGFBR2,TOPORS,CCND1,ARRDC3,CDK12,DLG3,SOD1,DIRAS2,SLC8A1,CARTPT,BANF1,MIR20A,EIF4A2,MET,LMO4,HPF1,KIT,CBL,TXN,PCNA,GSTP1,HYAL2,GH1,CCND3,MT3,CCNI,PARM1,PDCD10,RFC3,SPRED1,IGF1,DBNDD1,DKC1,TGFB2,CHP1,MAP2K3,DUSP3,CCR7,TLR6,GREM1,ADRB2,PROX1,PTPN22,RFC2,RAP2B,FEM1B,IL1B,AKT1,TNFSF15,AGAP2,HSP90AB1,CDKN2D,PRKAG1,CAV3,CAV1,MAD2L2,DSTYK,TNKS,TAB1,CDKN3,LCP2,SFN,UBE2I,LILRB4,RPS2,CD4,MIR21,UBE2S,EMP2,SOCS5,PKIG,IL4,RGCC,SMG8,PPP2R5A,RTRAF,IGF1R,TOM1L1,ERP29,MYC,FERMT2,PRDX3,HSPB1,DUSP19,FZR1,PPIA,CD86,GNAQ,CDC20,YWHAG,CCL5,MAGEC2,IL12B,EPHA4,TLR3,LDB2,FGR,EEF1A1,MAP3K12,HSP90AA1,SOCS4,SPRY1,PRNP,CDK5R1,PSRC1,ERRFI1,TPD52L1,INPP5K,SPINDOC,PIH1D1,TESK1,RB1,STRADB,CHI3L1,PSMD10,NHERF1,CDKN1A,ZNF622,MAPKAPK5,JMJD8,RFC4,CCL19,F2,DIRAS1,TRIB1,XRCC5,GSKIP,DDR1,CCNH,NEK2,LDB1,CCNF,CAMK2N2,TRAF6,GADD45A,RAP1A,TRAF2,HNRNPD,RFC5,CDKN2C,UBE2L3,PHB1,DUSP1,RPS3,SERTAD1,ADIPOQ,TNF,MAP3K11,CAMK2N1,ACTB,DUSP22,MIR24-1,CAB39,RPS7,FBXW7,BCCIP,DUSP10,STK38,PKIA,STK11,PYCARD,HRAS,FEM1A,CORO1C,FGF16,HEXIM2,CD40,RGS2,EPHA2,RALB,IL23A,UBASH3B,CHRNA7,EZH2,CEP85,PRIM2,RBCK1,IL34,PPARG,NTRK2,NTRK3,TCP1,MIR218-1,PAQR3,CAMK1,RPL23,NBN,CCNA2,CCNB1,CDKN1B,PRKCQ,MIR711,CACUL1,PDCD4,MIR15A,NEK7,MIR34A,SERINC1,TAF7,DIPK2A,CCNY,TCIM,TAB2,IFNG,KLF4,HEXIM1,PHB2,SPTSSB,TLR4,TRIM27,DLG4,LEP,HNRNPA2B1,CD200,PIK3CG,THY1,MIR26B,PTPRQ,PTGES3,FGFR1,RAP2C,WRAP53,ANGPT1,PTPN1,BAG2,SRC,GHR |
| 4.069e-07 | -14.71 | AGO2 (argonaute RISC catalytic component 2) | protein interactions | 27161 | 451 | 175 | 19454 | 5460 |
IGBP1,TSG101,PHB1,DNM2,FOLR1,MIR139,HNRNPA1,DICER1,RB1CC1,CDKN1B,HNRNPD,ZC3H7A,HNRNPA2B1,TRIP4,H19,TNF,G3BP1,MYORG,ACTN4,ZNF263,RAF1,MFAP3L,AP2S1,RPS11,MIR340,MIR769,CNOT6,PRRC2A,ACTB,SOCS5,CUL2,CUL3,LSM14B,MIR188,MIR363,HSP90AA1,YWHAZ,BRCA1,G3BP2,HAND2,YTHDF1,CYFIP2,MYH1,MIR579,IRF2BPL,LARP4B,PPARG,LDLR,EIF4E2,SRPRA,DFFA,NCBP2,CALR,MOV10,CRBN,GARRE1,CNOT6L,TRIM63,CNOT7,MIR15A,MAP2K3,DDX39A,YTHDF2,TBK1,MIR216A,ILF2,MLLT11,KRIT1,TRIM24,RPS20,PRKRA,SMAP2,MIR16-1,STUB1,CCNF,VIRMA,GMPS,USP14,PAIP2,AP2A1,MIRLET7I,MIR182,RPA3,MIR378A,MIR144,FUBP3,MIR612,HSP90AB1,HNRNPL,IQSEC1,MIR101-2,CNOT8,CPEB1,MIR29C,CNOT2,IFI16,MIR140,MIR221,AGR2,FKBP4,TRIM11,MIR183,RUVBL2,LSM14A,PABPC1,TFG,PELI1,HNRNPF,DCP2,SOX2,TOP3B,GLE1,MIRLET7B,ESR2,MIR324,MATR3,TBC1D1,HNRNPC,HNRNPAB,MYC,S100A11,DDX5,HSPA8,FOS,STAU1,FXR2,UFL1,NDUFS2,RPL27A,CNDP2,EIF4B,MIR204,PPT1,MCL1,SYNCRIP,SHPRH,FCHO2,MIF,CAND1,GAPDH,EDC3,COPS5,GPRASP2,MIR652,PEBP4,DHX9,ABCE1,MIR16-2,RBCK1,TNRC6C,TP53,IPO8,RRM1,NAA35,PSMC3,TAB2,PSMA6,CCSER2,DUSP3,RAPGEF5,MIR375,CEP85,PDCD4,IGF2BP1,RC3H2,RNF113A,DDX46,MIR107,MIR29A,TOMM20,EIF4E,GREM2,AGO1,MIR21,MIR142 |
| 4.079e-07 | -14.71 | Metabolism of polyamines | REACTOME pathways | R-HSA-351202 | 87 | 50 | 10285 | 3229 |
PSME2,PSMD6,PSMB4,PSMB9,SEM1,SRM,CKB,PSMC3,PSMA1,OAZ1,PSMD4,PSMD12,PSMC1,ODC1,SLC6A11,MTAP,PSMB2,PSMD1,AZIN1,PSMA6,PSMD10,SLC6A7,OAZ3,PSME1,SLC6A12,PSMD7,NQO1,PSMD14,OAZ2,NMRAL1,GAMT,ARG2,AZIN2,PAOX,SLC6A8,PSMD3,PSMB7,PSMB1,PSMB5,PSMA3,PSMC4,PSMA4,PSMC5,PSMB11,PSMA5,PSMB10,SAT1,PSMA2,PSMB6,PSMB3 |
| 4.094e-07 | -14.71 | response to molecule of bacterial origin | biological process | GO:0002237 | 354 | 148 | 18204 | 5365 |
NQO1,TLR9,PCK2,TSPO,TNFRSF1B,SLPI,GFI1,MGST2,MIR342,MYD88,IRAK4,CHMP5,CXCL13,OPRK1,CLDN1,CAPN2,MIR21,PTGER4,CDC73,MIR146A,CXCL3,TLR1,EPO,TICAM1,CYP27B1,ALPL,CD80,B2M,CD36,MEF2C,LDOC1,PRDX2,UGT1A1,BCL10,REN,FOXP3,IL12A,SRC,CD274,LILRB1,CSF2,IRF3,MIR140,PELI1,PDE4B,TLR4,FASLG,CXCL9,FOXP1,CXCL8,MIR223,IDO1,DEFB124,AKAP12,IL12B,TAB2,PDCD4,PTGER2,IL6,MMP9,SOD2,CAMP,CD86,IFNAR1,IL13,PRDX3,CNP,MIR142,RPL13A,THBD,XBP1,MIR20A,MIR17,HNRNPA0,TLR2,CD14,NLRP3,TRAF6,CCR5,TLR10,TICAM2,PLAA,CYRIB,TRIB1,PDCD1LG2,CYP1A1,LITAF,MAPKAPK3,CDK4,CNR1,FBXO3,CXCL10,FOS,JAK2,CCL2,ACP5,MIR105-1,MIR187,TIRAP,FOSL2,LTA,PTGER1,NFKB1,PRKCE,HDAC5,MRC1,IRF8,KCNJ8,CITED1,DIO2,CEBPE,HMGB1,PTPN22,NFKBIB,FMO1,AKT1,WDR83,IL1B,CD40,NFKBIL1,S100A8,FCGR2B,TLR6,CCR7,MTDH,CXCL1,PYCARD,STAP1,DUSP10,SELENOS,NFKBIA,PLSCR3,TNF,MAP2K3,IL1A,IL10,PTGFR,TNFAIP3,FGF10,GJB2,GSTP1,CX3CR1,PLSCR4,LIAS,CXCL11,IL18BP,LY96,TRIM6 |
| 4.126e-07 | -14.70 | IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) | protein interactions | 8517 | 436 | 170 | 19454 | 5460 |
ODAM,SUPT5H,PTS,TRAF2,HPCAL1,TNPO2,CAAP1,EIF1AX,POLR2D,NLRP2,MRFAP1L1,ARGLU1,RPAP3,TRIM26,EPHA4,TNF,G3BP1,SEMA4C,TRIM37,CCAR1,ENKD1,IRAK4,UBXN6,GSTM3,TAF7,PFDN5,INO80E,MAP3K14,SPATA2,IKBKB,TRAF6,PPM1B,PHB1,PSMB5,KRT8,CETN3,PRKCQ,NTMT1,PRPF18,EGLN3,HSP90AB1,RAB11B,MACROD1,LNX2,TANK,INSYN2A,CDKN1A,RNF7,CSNK1A1,SLU7,PRKD3,CD40,XRCC5,TRIM5,BIRC2,NMRAL1,TRIM22,DDIT3,PSMA3,UBE2D3,NSFL1C,RNF11,NRBF2,CREBBP,MYC,CUL3,RAB11A,BAG3,GCC1,RBBP8,PLEKHJ1,HSP90AA1,PHF7,AVPI1,NFKBIA,RAN,NFKBIB,ARPP19,PHF21A,HDDC2,TAX1BP1,TRIM29,TAB1,GADD45G,POLR2B,JAK2,TBK1,TP53,CDK4,EEF1A1,MLLT6,TFRC,TLR3,GINS4,RBM34,TAB2,PPP4C,MYD88,LTBR,CPNE2,CNOT7,RBCK1,FRMD8,ARF4,STX11,SMN1,RIGI,NFKB1,USP2,GTF2E1,TMA16,GLO1,TUBG1,BCL10,KPNA1,ID1,SSX2IP,FGR,HCLS1,AIP,NAP1L5,ITK,EEF1AKMT3,TES,ARF6,SURF6,AKR7A2,ATG16L1,LPXN,TPT1,ACBD6,NTPCR,TCP11L1,HSP90B1,WWP1,CNTN2,PDCL,SCLT1,GIT2,RNF34,PRKCB,SQSTM1,MAVS,NF2,KDM1A,NHP2,AKT1,TNFAIP3,MTPN,TRAF3IP2,DNAJC8,PPP1CC,RACGAP1,KPNA6,TRIM23,PIM2,STK11,CCHCR1,MAPRE1,VAMP3,OPTN,INHA,UBE2I,RPS12,DAPK1,PRKCE,UBB,IDE,TRAF1,SRC |
| 4.160e-07 | -14.69 | ROCK1 (Rho associated coiled-coil containing protein kinase 1) | protein interactions | 6093 | 172 | 79 | 19454 | 5460 |
ANKRD49,SMAD4,IKBKB,RHOG,LAMP3,HNRNPA1,NDC80,EDEM1,LAMP2,DPP4,NUF2,ZBTB2,PRNP,TRIM15,RHOH,IL18,ARF6,RAC2,TSG101,ADD1,DFFA,RAB35,HRAS,RHOBTB1,HGS,RND3,RAB4A,TPPP,HEXA,TP53,NAA15,ADD2,FLOT1,HNRNPK,ROCK2,KRAS,MLC1,HAPSTR1,NUDT5,PPP1R12A,UBE2H,SMAD2,CRMP1,RHOB,LAMTOR1,CFL1,RNF40,MORF4L1,CUL3,CDKN3,CUL2,LMO2,RAB2A,VIRMA,DES,SMAD5,ROCK1,SMURF1,MED17,RHOJ,PTEN,MSN,CCNF,GAB1,UBE2M,FGFR1,LMNA,MED23,ELK4,CDC42,UNC45A,CERS2,UFL1,RAB5A,EP300,HSPA8,ANAPC16,XRCC5,DNAJC3 |
| 4.160e-07 | -14.69 | UBXN4 (UBX domain protein 4) | protein interactions | 23190 | 172 | 79 | 19454 | 5460 |
RND3,PTRH2,RAB4A,RPN1,STIM1,DNAJC25,MTCH2,CCDC47,FKBP8,RAB3B,KRAS,IGF1R,FBXO11,SFXN1,TMT1A,CYP2C9,PEX3,ESYT1,RHOG,LAMP3,EDEM1,FAM20C,SLC25A46,RAB5C,MARCHF5,LAMP2,UBXN6,ATG9A,STX6,TMPO,LMAN1,DIRAS3,DERL2,ARF6,DNAJC1,RAC2,HSD17B11,GJA1,ACTA2,ARL10,RAB35,PTPN1,AIFM1,SSR1,RPA2,ST7,CDC42,SEC62,RND2,OTULINL,MTX2,TOMM22,DNAJC22,STX7,PXMP2,TOMM20,NSFL1C,RAB9A,MAVS,DERL1,RAB5A,AKAP1,SYVN1,HSPA8,EXD2,RPA3,FIS1,LMNB1,RAB11A,CIAO1,SEC63,TOM1L1,MAD2L1,IP6K1,MGST3,ODR4,SEC61B,RMDN3,PSMA6 |
| 4.259e-07 | -14.67 | CSE1L (chromosome segregation 1 like) | protein interactions | 1434 | 291 | 121 | 19454 | 5460 |
COQ8A,CD274,MTAP,PREP,CDC5L,DPP4,HDAC6,H2AC4,SLC2A1,KPNA1,PSME1,HAPSTR1,KPNA2,HUWE1,FBXO25,COMTD1,MVD,RRM1,NHERF1,RNF181,PPME1,CCNF,PTPMT1,ACAT1,SRP54,RHOJ,KCTD9,LDHA,VIRMA,BCCIP,RPL22,VAMP5,KPNA6,AR,DEPDC1B,CHORDC1,UBE2H,CDC73,PML,SIRT7,RPA3,BAP1,RNF113A,TCEA1,VIPR1,PGK1,FBXW7,HSPA5,CCND1,SMYD3,CFTR,GABRA1,CDC42,STOM,RPA2,HEXIM1,UBE2M,ATP6V1A,SUMO2,RHOH,HNRNPL,EGLN3,PDIA3,PSMD3,DDRGK1,XPO1,YWHAG,AGR2,UBFD1,XPNPEP1,HNRNPF,RRAGB,KRAS,G3BP1,UBE2A,RAF1,B3GNT2,EEF2,ERLIN2,FAF2,ISG15,AQP3,CHMP4C,EZH2,CYB5B,MOB3C,RAN,LMBR1L,STAT1,PSMB6,PPP5C,CUL3,GPR17,ACO2,MYC,RHOB,LMNB1,BRCA1,CKB,RIT1,XRCC5,CD40,NUP50,PMAIP1,EP300,BIRC2,TXNL1,HACD1,HDAC5,STAU1,RP2,UFL1,EMC1,UCHL3,NPTN,UNC45A,GINS3,RND2,PLAA,PIH1D1,CNDP2 |
| 4.270e-07 | -14.67 | Regulation of Apoptosis | REACTOME pathways | R-HSA-169911 | 54 | 35 | 10285 | 3229 |
PSMD6,PAK2,PSME1,PSMB4,PSME2,PSMD10,PSMD7,PSMB9,SEM1,PSMA1,PSMC3,PSMD14,PSMD4,UBB,UBA52,RPS27A,PSMB1,PSMD3,PSMB7,PSMD12,PSMC4,PSMC1,PSMA3,PSMB5,PSMB11,PSMC5,PSMB10,PSMA5,PSMA4,PSMB3,PSMA6,PSMD1,PSMB2,PSMA2,PSMB6 |
| 4.318e-07 | -14.66 | SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor) | protein interactions | 6830 | 211 | 93 | 19454 | 5460 |
PIH1D1,SUPT4H1,CDKN1A,COIL,FBXW4,SLU7,SNRPA,NUP50,EP300,FTSJ3,BRCA1,PSMD14,DNAJB6,RIT1,PFDN2,PFDN4,LMO2,OST4,MYC,CREBBP,SNRPB,RNF40,MED17,SNRNP40,ESR2,POLR2B,POLR2F,MCPH1,EZH2,POLR2C,POLR2D,SUPT5H,PI15,KIAA0408,RUVBL1,S100A10,KRAS,SSRP1,RPL31,HSPD1,BAG2,FAM168A,RUVBL2,RPAP3,DEGS1,DCAF5,DDX23,WWP2,BAZ1B,HNRNPL,FBXO32,POLR2L,CCDC71,RPRD1A,EED,HSP90B1,RPA2,RPRD1B,HAUS2,PAAF1,HMGB1,FBXW7,HSPA5,SIRT7,RPA3,TCEA1,ELOF1,STK11,AKT1,PPP1CC,GMNN,VIRMA,SRPK2,ZNF330,CCNF,GAB1,TRIM24,MACROH2A1,TP53,RPAP2,H2AX,MDC1,RIGI,RNF20,H2AC4,TUBG1,SUV39H1,CSNK2A1,TMA16,TOP1,SPPL3,TMPO,RCHY1 |
| 4.331e-07 | -14.65 | CLEC7A (Dectin-1) signaling | REACTOME pathways | R-HSA-5607764 | 101 | 56 | 10285 | 3229 |
TRAF6,PSMD6,PSMB4,CLEC7A,IKBKB,UBE2D1,PSME2,PSMB9,SEM1,IL1B,PSMA1,PSMC3,PSMD4,PPP3CA,UBE2M,RPS27A,MAP3K14,TAB2,BCL10,PSMD12,PSMC1,UBE2N,UBE2V1,PSMA6,PSMD1,PSMB2,PYCARD,SRC,UBA3,SKP1,PSME1,PSMD10,PSMD7,NFKBIA,PSMD14,UBB,UBA52,SYK,PSMB1,AHCYL1,PSMD3,PSMB7,PSMC4,PSMB5,PSMA3,TAB1,PSMC5,PSMB11,PSMB10,PSMA5,NFKB1,PSMA4,PSMB3,PSMA2,PSMB6,FBXW11 |
| 4.382e-07 | -14.64 | regulation of biosynthetic process | biological process | GO:0009889 | 5686 | 1817 | 18204 | 5365 |
EP300,RFC3,PIK3R3,WDR77,OVOL1,BACH1,LSM14B,ANXA7,TMEM106A,GPX1,LMNA,ZMYND11,ZNF862,GMNN,AKAP17A,MIR136,PRMT5,MIR99A,MIR92B,H2AC6,MIR9-3,DRD3,AMELX,TANK,SELENOS,MAF1,MIR573,BST2,PKIB,TIRAP,RAMP3,KPNA6,GSK3A,DEDD,AATF,SNX12,ODAM,MIR206,MLLT11,MIR643,H2AC4,CTDSP1,PHF21A,CDK12,TRIM24,MSN,CRKL,FOXP1,MIR190A,STOML2,DUOXA2,MIR185,PCBP4,POLR3B,RNF14,IL12B,UBE3A,USP2,MIR1-2,RSAD2,BGLAP,MIR107,ZFP64,JUN,PNP,MORC2,HSPD1,CBX3,MIR885,MTA3,GNMT,MIR449A,ZFP1,FLOT1,EMX2,CXXC1,ELK1,LYAR,SIN3A,EIF4E3,MIR210,POLR3F,MIR593,MIR33B,RMND1,ZNF592,POU5F1,MIR197,H3C1,MIR651,ABCC2,POGK,MIR548C,ZNF280B,ILDR1,MYBL2,RGCC,TIA1,MIR375,LILRA2,MSX2,MTG2,MIR30B,INHA,MIR519D,RBFOX3,ELF5,SCML2,SLC7A11,MIR24-1,SMAD3,CSRNP1,DUSP22,HNRNPD,WNT2,CCN3,TAF9,KMT5B,EIF4A3,IRF2BP1,TRIM62,TMIGD3,SELENOK,MIR205,SETD5,MIR924,MIR599,KLF10,PCGF3,ATF3,ZNF32,FCGR2B,ELP3,MIR653,STAP1,PRSS37,IRF2BPL,FOS,CHI3L1,PSPC1,HNRNPF,RPAP2,ARG2,NFKB1,ZKSCAN1,LRIF1,PLP1,SUPT3H,MIR937,HLF,NUDT12,MIR1180,MIR181D,MIR802,POU3F4,TRAF6,TICAM2,HP1BP3,MIR222,CCL19,HOXD12,TRIB1,MIR378A,PLAGL1,RNF40,TENT2,BIRC5,ZBTB5,IFNG,PRKRA,MEF2A,MIR135B,LGR4,PTGES3,SRGN,NRDE2,MIR34C,CDK20,SRC,PPID,ZNF609,ANGPT1,HEXIM1,TRIM21,NOVA1,ATF4,ZNF22,HNRNPK,SMAD9,TICAM1,MIR181C,MIRLET7I,MECP2,BMPR2,EDC3,TAL2,MIR29A,EXOSC3,CELF6,MIR542,MOG,PQBP1,IRF1,ITM2B,AFAP1L2,UTP15,INSM2,IFI16,STARD4,NTRK2,LMO3,DDAH2,MIR551A,CCT5,CTNNBIP1,TCEAL7,METTL14,ACTR2,NOTCH2,SRPK2,RBM7,SVIP,RASL11A,CRIP1,ACTA2,HNRNPH2,TGFB2,CHP1,CRYBA1,PAK6,METAP1,MIR144,MIR612,RING1,PCNA,ZBTB38,MXD1,TRIM37,IRF2,USP13,PTPN22,SOX2,NFKBIB,PDE8A,ABHD14B,PXYLP1,HSBP1,CCNQ,CDH13,PIWIL2,MTDH,ADTRP,GREM1,MIR940,ATP2B4,MACROH2A1,RIT2,MIR708,ZC3H14,ZNF174,PAGR1,CTBP1,PRKCB,SHC1,ZNF250,TRAF3IP3,HBP1,CCL21,MIR20A,TADA3,NFE2,CIRBP,BAZ1B,ATP1B1,CDK7,MAFG,SPON1,G3BP1,DNAJC30,THOC2,GLO1,WWP2,MIR216B,HNRNPA1,FRMD8,CREB1,MIR556,TDRD7,PRDX3,APOBEC3G,SASH3,CD83,PSRC1,MIR190B,HTR2A,INPP5K,GATAD1,APLN,MOV10,KLF9,SAP30BP,SMAD5,HSP90AA1,TGIF2,CDK5R1,H2AC13,KDM4B,MAGED2,SP4,TRIM11,SMG5,RC3H2,VGLL4,ERLIN1,HSP90AB1,CBFB,TAX1BP1,CD28,BEND5,MEF2C,ZCCHC17,MSTN,IFIH1,MIR208A,PKIG,ZMYM2,ZMPSTE24,RUNX1,GFI1,TAF2,WWP1,ZGLP1,HBEGF,AP2A1,TRIM26,ZBTB42,EGR2,LILRB4,RPS27L,ARB2A,ADIPOQ,LBH,FGF17,YAF2,MIR567,H2AZ1,ROCK2,NMBR,CBX5,TRAF2,FOXP4,ETF1,EEF2,RPS3,TRIM6,MIR495,YTHDF1,CXXC5,INO80C,ZNF770,EPHA2,LARP4B,S100A10,AGER,MIR361,ZNF304,MIR23A,BATF,PSMD10,TNFRSF14,CXCL10,SPHK2,JPH4,SPINDOC,H2AX,FBXW11,RAG1,MIR424,OGG1,DIS3L,MTRES1,TFDP2,XAF1,LDB1,CGGBP1,MIRLET7C,MIR657,RHOH,MIR581,ACOT8,MIR1277,TAF7,IDO1,TENT5D,ZNF451,MITF,VPS72,MIR216A,CLEC7A,IL21,MIR34A,TMEM14B,IL13,MIR609,ZNF671,ATXN1L,FGFR1,HELT,PIWIL4,ACSS2,MIR155HG,VGLL2,SCAMP5,ENC1,CKS1B,HUWE1,PTPN11,HDAC11,NONO,CDK6,TFPT,FOXI3,TRIM27,RAD21,POLR2L,LSM6,SLC6A4,GAPDH,MIR934,TGFB1I1,MYRF,CNOT7,FZD6,ESR2,ITK,MIR1262,IL7,RFXAP,EZH1,IER2,RNF20,BTG2,TSPO,ZBTB6,DCP2,GPNMB,JUP,MIR711,RNF187,CYP7A1,MIDEAS,SP1,CCNA2,MIR626,PTGER4,SFRP4,RPL23,SAP30,NFKBIA,CLK4,PPP1R11,BRD9,MIR331,TCF23,SIRT7,BAK1,VDR,TEF,ZNF688,MIR345,MIR877,CEBPE,MIR374A,VSTM2A,WNT7A,SIAH2,TGFB3,DUSP26,ACO1,RPS4X,FUBP3,RPL26,CCT7,SERTAD2,ITGA2,TCEAL1,PHC1,TAF11,FGF1,MIR125A,ACP5,MIR187,GNB3,MIR450B,RGMA,SMU1,MIR10B,DIO2,ATF1,RPL13A,XBP1,MED13L,PID1,HIRA,CCND1,TSC22D3,PAIP2,CYTL1,MIR130A,IL2,MIRLET7B,SOD1,AR,MIR492,MACIR,GNRH1,MAGEC2,ZNF513,MMP14,TP53INP1,ZNF581,ZBTB2,EIF4E,ID4,BAHD1,PTP4A3,CHMP1A,PADI2,PPP2CB,PPP1R12A,ACTL6A,FOXP3,CD274,MIR1224,HAX1,LMNB1,E2F4,TENT4A,SMARCE1,KLHL25,SMYD3,GFPT1,PAX6,RIGI,MIR577,WNT10B,TXNIP,TP53INP2,MIR887,PRKAG1,MIR454,IFNK,SMARCD3,HDAC3,MIR148A,ZNF24,ZBTB16,MIR383,NACC2,DNAJB6,SFN,MIR96,ZNF507,MIR648,MIR363,APBB3,VSIR,MIR101-1,TRIM32,TRMT112,GPAM,UBE2L3,MAGEA4,MED9,ZSCAN25,MED23,LAMP3,SERTAD1,CNOT6L,RASD1,HILPDA,FGF16,PITHD1,SYK,NLRP1,HNRNPL,BOLL,PRDX6,FBXW7,EAF2,PRR5L,TESC,NOG,S100A8,EWSR1,APOBEC3C,MALSU1,TRIM5,SELENOT,MIR129-2,NPPC,IGF2BP1,PSMC5,CLEC9A,CCL2,CHCHD2,RBM42,ARL2BP,EIF5B,DNAJC1,POU1F1,PDE2A,CIART,SERTAD3,C1D,APOBEC3A,H2AC1,MIR373,ZNF287,TACO1,VAMP3,PIAS1,CYRIB,TBK1,XRCC5,CDK4,MIR632,MIR32,ZBTB39,NOSIP,TAF1D,IL17F,TAF10,CD47,PIK3CA,ZC4H2,APEX1,ROCK1,SUPT4H1,PHAX,MIR15A,H1-3,RB1CC1,KLF3,CCDC85B,CD58,MIR140,TFEB,PDE4B,MIR939,CD40LG,NSMCE3,NUDT16,MTPN,EIF3E,FGF23,PPM1B,CLK1,MTA2,IL23A,VEGFA,SATB1,ZNF704,MIR944,KLF1,PIK3R2,MIR301B,PRKACB,OSM,CCL1,YWHAZ,SOX14,DEK,FZD4,KRBOX4,CAPN2,CAMK1,PARM1,PLD3,MAP2K3,MIR192,LRP3,PAOX,RERE,ZNF596,OTUD7B,RPRD1B,MIR9-1,SCAND1,LSM2,RFC2,MIR600,DKK1,HOXB1,MIR367,GLRX2,RNF8,STAT6,CCR7,HAND2,PRDM4,MBD3,LCORL,SRSF7,DDX4,ADRB2,CD200R1,EIF4EBP2,CDC5L,MIR339,PPTC7,NR1I2,PRPF19,TRIM29,ING5,PELO,SAP30L,CCR1,IRF8,NUCKS1,MIR558,HOXC4,DHRS7B,PAEP,GHRL,CPEB1,CSNK2A1,HNRNPA0,SOX9,NDFIP1,SART3,MIR489,SNAI2,ZNF7,DCAF5,RBM23,RORB,CCL5,DMTF1,RPS14,TLR3,TRIM68,AKAP12,DYRK2,MIR3173,MIR761,MIR484,ZNF652,MIR302B,FLCN,SECISBP2L,NUPR1,CRYAB,AGO1,MIF,HNF1B,BCL10,MIR132,IL12A,RWDD3,EIF5A2,MAP3K12,HEY2,IRF3,SETD7,STK3,ZNF518B,KLF12,MIR1225,GPBP1L1,CHID1,MIR101-2,CPTP,MIR452,TADA1,SPIN3,LANCL2,MIR150,ING2,RUVBL2,DKK3,THAP1,MDC1,MIR504,IL4,ILF2,MIR662,FAM98A,SCML1,MIR146A,DGCR8,NKRF,CX3CL1,MIR1298,NGRN,ANKRA2,MUL1,FCGR2A,MIR624,MID1IP1,PHB1,ING1,FGF7,PLAC8,MIR615,HEXIM2,CDK5,MIR98,KDM2A,MIR649,PKIA,CCT8,GTF2A2,MIR628,SUPT5H,TENT5C,LSM14A,TOP1,MED4,MIR105-1,CDKN1A,MDFI,MIR16-2,EID2,RPL6,ILK,TMEM107,TAFAZZIN,ZNF655,MIR301A,NLRP2,ZHX3,PPM1D,ZBED4,MIR502,MIR214,H2AB1,NLRP3,CASC3,CLDN3,H1-5,FUT8,IRF4,PDCD1LG2,MIR552,SDCBP,HENMT1,MDM2,MIR188,TP53,MIR583,MIR1-1,NCBP2,DDX5,ZNHIT3,ZNF473,INTS10,BAG2,CSRNP3,HSPA8,PAX9,MIR147A,JADE1,ZNF790,CER1,ZNF692,MIR335,KPNA2,CYP27B1,ZNF189,ZBTB14,TRIM15,MIR195,ZNF526,FAF1,PIWIL1,ZNF326,MIR198,MIR1249,DROSHA,HEXB,TRA2A,CDKN1B,TRIM52,MIR193B,MIR218-2,HOMER3,FOXJ3,RBM15B,UFL1,RBM3,MIR384,SNX5,DR1,PDCD10,MAGOH,EIF3D,NAA16,KARS1,CTNNB1,SP2,MIR1227,SHLD1,HYAL2,KLK5,H2AC7,TSNAX,GPT,UBE2V1,EID2B,MIR1271,MIR578,NOP53,MIR938,LSM4,RNF128,SMAD4,INO80E,MORF4L1,MED31,FBXL19,MIR500A,JAK2,PTEN,MCPH1,LMO2,USP3,CAND1,STAT1,LRP6,DVL2,LACC1,CRY1,DEFB114,CD34,SMCHD1,ABCE1,RAB27A,TNFSF13,CREBZF,MIR377,RIOK2,GRIA1,LMO4,EIF2AK2,CD14,RLN2,SS18,MIR155,MIR221,PSMC3,UBE2N,CARTPT,SLC8A1,RRN3,MIR497,NCOA5,THRAP3,LDB2,RNASEL,FGR,ERP29,GTF2F1,RFX5,CSK,ABHD6,MIR633,BTG1,ZNF267,MIR186,JUNB,OTX2,PRL,TRIM34,HAS3,ENO1,LDLR,DMAP1,MIR10A,NEUROD2,ZNF263,PELI1,PPARA,IFNGR1,RXRG,PC,MED29,IFI27,BAP1,RBBP9,MIR129-1,CD36,SRSF10,FOXD3,IREB2,TCF21,DXO,NOS1AP,DNM2,MIR330,NGDN,SYNCRIP,CREBL2,CPNE1,ELP6,WDR82,ANAPC2,MIR21,ECD,CKS2,PCBD1,NR2F6,MAGEB10,CRTC2,TUSC2,SERPINB1,PNRC1,MIR920,ELOC,TFRC,MIR23B,CLU,MACROH2A2,OTULIN,MED30,NKX3-1,NFKBIL1,RPS7,PKNOX1,BMPR1B,TFCP2,HCLS1,PML,EIF2S1,MIR141,SNAI3,MIR491,TERT,PABPC1,NEK2,CD2AP,CD38,FXR2,GADD45A,NDP,FKTN,ZBTB25,SFTPD,TLR5,H2AZ2,MIR34B,MIR873,DYNLL1,MIR7-3,MED17,STK16,HOXB8,MIR765,EIF1B,SMARCA5,PIWIL3,ZNF740,MIR148B,TCOF1,ZNF175,PHB2,MIR601,CD200,COMMD6,POLR2G,SQSTM1,LEP,MPV17L2,PRMT6,SOX3,DNAJB4,NFE2L2,BMPR1A,SMARCB1,DRAP1,MIR549A,SEMA7A,TFE3,SRSF4,MIR625,GTF2IRD1,MIR100,BRMS1,TRIM3,NTRK3,ZNF319,MIR296,MYT1L,TLR8,CIPC,MIR563,MIR618,CCDC3,EIF3K,RFXANK,MIR153-1,EIF4EBP3,EIF2B5,KRAS,DPY30,IL1A,PPP1R3C,FGF10,TF,IRF6,IL2RG,NCK1,GCLC,WASL,DYRK1A,ZNF177,KLK3,MIR152,PROX1,TNFSF18,CREBBP,MIR147B,ZBTB18,CCT2,MIR200C,MIR425,SMAD1,IRF7,NLRP6,MIR1260B,ZSCAN1,ACTN4,ZBTB26,XPO5,FOSL2,LTA,COPS5,SUMO1,CDCA7L,HNRNPC,DIRAS3,OAS1,TWIST2,SETD3,IDH1,MIR656,TRIM22,MTF1,AIP,PYM1,LITAF,PICALM,CASK,MIR106B,ITM2A,GPSM3,FITM2,DLX1,LRRC14,SSBP2,MYC,MIR184,MIR126,MIR553,DAPK1,MIR490,HSPB1,MARS1,MIR142,MIR105-2,PDCD5,APOBEC3D,DDT,ATP6AP2,SNIP1,CDK1,OSR2,RPS6KA4,MIR194-1,MIR557,MED21,EED,NFIL3,TNFSF8,CTDSP2,PPP1CB,MEPCE,RBBP8,CAV1,IFNB1,RBFOX2,TNKS,MTG1,MEAF6,PIM2,RAB1A,SUPT7L,RBM22,IRF9,ZNF397,MIR342,SMAD2,SLC38A3,BRCA1,ALKBH5,BUD31,MIR31,APOBEC3F,UBE2I,SNRNP70,ZHX1,ZNF687,MIR324,CD4,PSEN1,TNKS2,MIR636,DDRGK1,CRLF3,POLDIP3,NAA15,MIR505,RBBP7,SRSF2,ARMCX3,RAF1,MIR611,IL10,MIR640,FERD3L,STN1,PTGFR,TRAF1,TAGLN3,RFC5,NKX6-2,MSX1,MIR145,CX3CR1,ZSCAN5A,LY96,BCL7B,HMGB1,SSBP4,LBX1,RGS2,MIR875,HNRNPH3,GTPBP1,GABPA,HRAS,PYCARD,INPPL1,ZNF593,RFC4,USP16,APOBEC3B,BHLHA9,NFE2L1,ZBTB45,TRA2B,CGAS,DAP,ADNP,PRKCA,BRD3,EIF4E2,ACVR1,POMT2,CCR2,F2,PLSCR1,BCL7C,SLC35B4,MIR133B,CXCL8,FKBP8,CYGB,ITGA6,MIR770,UBP1,ATG101,UBE2D3,MIR340,P2RY1,SRSF1,NKAP,SIX5,FGF22,ADORA3,SMG9,TOMM70,MIR590,DNAJC2,POLE3,MIR586,DDIT3,NR4A2,MIR28,MNAT1,EPO,ZNF664,MIR422A,EGR1,IKBKB,IL34,MKKS,YTHDF2,EIF4H,NCSTN,NFYB,MIRLET7G,CHRNA7,MIR554,EZH2,UPF3B,UFD1,MIR193A,F11R,SLA2,PRKCQ,SESN2,MIR106A,PGR,ZNHIT1,PPARG,EMX1,CCDC22,MIR30A,IGF1,MIR604,HMX2,PTRH2,DKC1,ENY2,CNOT2,WTAP,GRSF1,MIR675,CALR,SKIC8,MIR639,TNFAIP3,RBBP4,TXN,GSTP1,MAX,MT3,CREB3L4,MXI1,INPP5E,NEUROD6,TOX,CCND3,SLC45A3,MIR182,ELAVL4,PPP3CA,CLP1,AKT1,DYRK1B,MIR569,IL1B,ZNF787,MTERF2,SLCO3A1,EXOSC8,TLR6,AGR2,MIR595,MIR211,EIF4B,E4F1,TSG101,NR1H2,CDK5RAP3,ZNF343,MIR448,MIR631,MIR320A,EIF4A2,MIR1251,MET,KIT,PHF1,TGFBR2,UBE2D1,HNRNPAB,NKX3-2,MIR223,G3BP2,ELF1,DDX1,ERLIN2,FCER1G,MIR379,TRAF3IP2,EFCAB7,IL6,AGPAT1,TOM1L1,CD86,PYDC2,LSM5,PAIP1,SOX21,PSMA6,AKT2,COPS2,UHMK1,FOXN2,HMX1,MATR3,PRNP,MIR130B,CARHSP1,SF3B4,MIR589,MIR607,DAPK3,MAD2L2,SSBP3,IKZF2,ZBTB33,CLEC6A,MIR204,ZNF576,MIR423,NMI,FOXS1,GABPB1,UCN,ANXA4,CD80,TAPBP,MED27,GTF2A1,TLR9,PLCB1,KCNIP3,ORMDL1,TNFRSF1B,MLLT6,ADM2,MIR196B,MIRLET7D,SMG8,E2F6,METTL18,RPL10,MIR580,LPCAT3,IFNA2,MEF2B,CDC73,FABP4,DNAJC3,CD2,NIF3L1,SPTBN1,TCEA1,ATRAID,TNRC6C,PRKAB1,ASB1,HR,YES1,BIRC2,STAR,NR1I3,MED10,ACVR1B,TMBIM6,CD40,MAGEB1,FOXA3,MIR616,NME2,INTS12,MIR208B,SGF29,HDAC6,CREB3,STK11,ALKBH4,MIR592,MED22,CCAR2,MAP2K6,MRTO4,H2AC25,MIR7-1,MAPKAPK5,ZNF805,NUP62,WBP2,RDH10,MIR16-1,PIH1D1,ZNF575,MRPL12,GTDC1,MRPL13,HNRNPDL,CCNH,TLR2,RPS13,MIR183,GCHFR,CYP1B1,PTHLH,AKAP8L,RNF10,RNF26,STAT5A,VIP,VRTN,IFT52,CBX7,MIR139,PDCD4,NEO1,STAU1,ETV6,MIR143,MAGOHB,MIR891B,MIR572,GTF2H2,IL18,ELK3,WRAP53,UQCC2,BZW2,EID1,HNRNPA2B1,PIK3CG,INSIG2,FASLG,TLR1,MIR137,MIR769,IL15,MIR455,MIR298,MIR194-2,FABP5,MIR532,BCL9,SLC38A2,MIR652,MIR874,CCAR1,NR2E1,PIK3R1,RAN,MIR24-2,CUL3,SETD4,NR0B1,MIR922,MIR30E,FOXP2,MAGED4B,TCP1,MIR218-1,H2AJ,ELK4,NIBAN2,ISX,CRYM,TRUB1,MIR493,MIR346,MIR449B,NEDD8,RLIM,MIR370,MIR597,LTB,TLE1,TRIM8,MSL2,MIR517B,MIR30D,DHX9,RABL3,SPP1,MIR25,UAP1,ISG15,THAP7,MIR1226,ZNF501,BHLHE40,HCFC2,ZNF345,RGMB,IL5,EDF1,TLR7,MIR29C,ZBED1,BUD23,TSN,KDM1A,MIR936,TOB2,STPG4,MIR511,HDAC5,MAP2K1,PPP1CC,HGS,PRMT2,MIR488,ANKRD49,IL1R2,MIR551B,SUB1,RGN,EXOSC4,MIR429,STAT2,TOPORS,ZCCHC7,DICER1,HBB,DNAJB9,BANF1,IKZF5,IGBP1,SF3B5,CNOT6,MIR215,DLG1,ZNF322,MIR605,MIR200A,EPHA4,DEFB124,MOSPD1,ZNF821,MIR942,MIR7-2,PELP1,RBM12,CSNK1E,RTRAF,IGF1R,MAGEH1,SFRP1,PPIA,YWHAH,ID1,CCL3,LILRB1,BTN2A2,STOX2,RFX4,CSF2,IL6ST,GTF2F2,BARX2,SRSF12,MIR876,FASTKD5,TYROBP,MIR661,ZBTB17,MIR760,MAVS,FURIN,KANSL3,RPS9,TOX4,BEND6,IL20RB,SOCS5,HSPA5,MYD88,NPTN,TAF5L,CD46,MIR149,ZNF436,NLRP9,ARPP19,TULP3,CD81,TWSG1,FGF3,ACTB,HMGA1,TNF,SHMT1,MIR9-2,BRMS1L,XCL1,NAB2,SF3B1,RBPJ,CDK8,AVPR1B,ATP1A1,MIR191,RUVBL1,PDE12,EDA2R,ORMDL3,TOP2B,SSU72,DDAH1,HMG20A,BCL6,SH3BGRL,HFE,PFDN5,CTDSPL2,EMILIN1,ELAVL2,MED11,ITGB8,HINFP,FBP1,MIR1296,LURAP1,TCF19,ZNF511,MZB1,IL1RAP,NFYA,RIOX2,TMSB4X,CDK9,RBM5,DRGX,NDN,SDR16C5,PHF12,MIR338,NAB1,TYMS,CITED1,RB1,RNF141,GJA1,MIR17,CNTN1,RBM38,PAIP2B,CEBPG,MIR764,AIF1,FOXC2,NEUROG2,ACTL6B,MIR671,CIAO1,MAEL,EPOP,SOST,LEPR,NEK7,SOD2,ZNF362,PCGF6,ZC3H7A,ASCC1,MIR99B,CNOT8,CRABP2,TRIP4,PCGF2,SAP18,ZNF574,MIR26B,CIAO3,RAP2C,KLF4,ZBED3,TMEM14A,TGIF2LX,ARF4,TLR4,APLNR,RNF139,ZNF668,MIR638,LUM,C1QTNF1,HMCES,HINT1,RBCK1,APOC2,TRIM44,RPS26,IFRD2,B2M,EIF2B2,LHX2,PRIM2,GTF2I,TCEA2,PLGRKT,HELLS,KLHL22,IMPACT,SUV39H1,MLF2,SUFU,RHOG,MIR503,MIR212,MLF1,APOBEC3H,EPCAM |
| 4.424e-07 | -14.63 | response to abiotic stimulus | biological process | GO:0009628 | 1100 | 398 | 18204 | 5365 |
EGLN3,BIRC2,TFRC,ASIC1,TRIM32,HNRNPD,PARP2,SMAD3,SLC7A11,SLC2A1,CDH8,NR2F6,STC1,CCAR2,STK11,HDAC6,NOG,AKR1B1,NKX3-1,CD40,WDR83,NLRP1,FGF16,HILPDA,GNA11,DRD1,CRADD,KCNJ8,TERT,NFKB1,CACNB4,EIF2S1,DCUN1D3,PDE2A,PML,DISC1,CHI3L1,FOS,H2AC25,CLCN6,NGB,NPPC,XRCC5,PIAS1,TLR5,PICK1,DPP4,NDP,SLC12A2,HP1BP3,GADD45A,TLR2,KCNJ3,THBD,CD38,TCIM,NDUFS2,F7,PIK3CA,DTL,TCAP,FBXL3,LEP,TM9SF4,ATF4,MIR140,BACE1,HIKESHI,PHB2,PSEN2,PPID,SRC,DAG1,FAM162A,SST,GTF2H2,KCNJ11,MGARP,EXT1,BNIP3L,TIMP1,VEGFA,SLC38A2,TMEM199,MECP2,RRM1,MTPN,NFE2L2,DNAJB4,NSMCE3,PDE1B,HSPB6,EIF2B5,CAPN2,FZD4,TLR8,IFI16,PGK1,SLC52A3,ELOVL4,IRF1,PIK3R1,GPX1,RETN,OXTR,MT3,HYAL2,SLC1A2,MAP1B,BAK1,AGTRAP,TXN,SLC1A1,CTNNB1,CYP2R1,KARS1,CALR,DIO3,UCP2,EP300,NFKBIA,IGF1,SMAD4,TANK,ITGA2,DRD3,RPL26,TGFB3,IL1B,NDNF,NOP53,KCND2,AKT1,AIFM1,LMNA,TUBA1A,BAD,MIR448,KRT8,EGLN2,CRY1,PRKCE,STAT1,FGF1,PTEN,BCL2L1,SLC8A1,SOD1,TRIM63,MSH6,TSC22D3,CCND1,KIT,CD14,FAS,TERC,GRIA1,CYB5R4,ADRB3,MIEF1,GNAQ,ACAA2,BGLAP,MMP9,BAX,USP2,TP53INP1,IL12B,MMP14,MIR223,SLC2A8,SLC1A3,VEGFC,PPARA,ADRB1,NEUROD2,GRM1,OXSR1,HSPD1,AKT2,GJA10,BABAM1,PMAIP1,UCN,MIR210,EDNRA,TXNIP,AQP2,ADSS2,ELK1,GPR65,DNAJC3,MIR21,UBE2B,RGCC,ATG7,PPP1R1B,DBH,ATP1A1,RAF1,RBBP7,TNF,ADIPOQ,MAPK10,RHOB,HRAS,PYCARD,AGER,PCLAF,FBP1,CAB39,CXCR4,KCNMA1,CDK5,TOPBP1,PLAC8,RAB11B,CXCL12,MME,STUB1,OGG1,LRRC8D,RAG1,GUCY1B1,ADO,H2AX,ASIC2,CDKN1A,DRGX,HSP90B1,CXCL10,NHEJ1,SLC25A27,CLDN3,SLC29A1,AIPL1,NLRP3,SCN2B,MIR214,MIR17,PPM1D,GJA1,IL13,MIR34A,SOD2,SOST,GNGT2,HPCA,CYGB,TP53,FKBPL,RCVRN,ERCC3,TAC1,LPAR1,MDM2,LRRC8A,EYA3,SLC4A10,TLR4,HMOX2,DCLRE1C,CCL11,MICB,CLCA1,LXN,NETO1,HSPA8,CIAO3,GHR,ADORA1,LARGE1,COMT,RAD1,P2RY1,ANO3,TMEM87A,CHRNB2,CHRNA7,ATAT1,EIF2B2,MKKS,FANCG,EGR1,EPO,SLC6A4,RAD21,NR4A2,PTGER4,CCNA2,PPARG,SCFD1,LIPA,SUV39H1,JUP,F11R,CDKN1B,COP1,BTG2,TSPO,NQO1,STRBP,CPT1B,EIF2B3,KCNMB1,AANAT,PCNA,GTF2H5,CLPB,IL1A,CHP1,TGFB2,POLB,CRIP1,KRAS,ADRB2,CREBBP,FUNDC1,BHLHE40,REEP6,DDIT4,RNF8,GLRX2,HSBP1,ATP6V1G1,COL3A1,SOX2,GCLC,SUMO1,NUCKS1,MAP1LC3A,PPP1CC,MAP3K14,LTA,FOSL2,GAD2,KDM1A,TLR7,NABP1,ATP2B4,RAB3A,CYP1A1,ATP1A2,LRRC8C,LTBR,SNAI2,BECN1,CBL,SOX9,FEN1,ERO1A,BAG3,FZD3,CIRBP,CPEB1,MIR20A,GHRL,HSPB1,CRYAB,SLU7,HSPB2,SFRP1,MIR126,IGF1R,MYC,AKAP12,TLR3,MIR106B,KCNC1,UBE2A,RNF34,HSP90AA1,SOD3,IL12A,HTR2A,BCL10,KCNJ2,RUVBL2,CAV3,MSTN,HSP90AB1,CDKN2D,CAV1,MCOLN1,ATP6V1A,PPP1CB,MIR146A,PTN,TXNRD2,AQP3,SERPINB6,BRCA1,ABHD12,ALKBH5,MYD88,TACR1,ZMPSTE24,HTRA2 |
| 4.469e-07 | -14.62 | Chemokine signaling pathway | KEGG pathways | ko04062 | 182 | 95 | 7161 | 2463 |
CXCL1,GNB4,CXCL10,CCR3,CCL4L1,PRKACB,GSK3A,CCR7,HRAS,SRC,NFKBIA,CCL19,ROCK2,GNG13,RAP1A,CXCR4,CCL11,GNG3,FGR,CCL5,GNG10,CXCR3,WASL,RASGRP2,RAP1B,CCL25,CCL17,JAK2,PLCB2,CX3CR1,AKT1,CXCR1,PIK3R2,GNAI3,CCR4,CRKL,CCR2,CCL21,IKBKB,GNB3,NFKBIB,CCL18,CXCL3,ITK,GNAI2,CCL23,ROCK1,CCL2,SOS2,GNG5,PIK3R3,CCL3,ADCY3,GNG7,SHC3,CX3CL1,RAF1,CXCL8,CCR6,NFKB1,CCL20,GNB1,AKT3,CXCL9,CCL1,CCL24,ELMO1,ADCY2,CCL8,STAT2,MAP2K1,CCR1,CCL28,CXCL13,GNG12,CDC42,CXCL11,KRAS,CXCR6,GNGT2,CCL27,PIK3R1,TIAM1,VAV2,SHC1,PLCB1,PRKCB,AKT2,STAT1,GNG11,GNG2,CCR5,CXCL12,PIK3CA,RAC2 |
| 4.469e-07 | -14.62 | Chemokine signaling pathway | KEGG pathways | hsa04062 | 182 | 95 | 7161 | 2463 |
GNG10,WASL,CXCR3,RASGRP2,RAP1B,CCL25,CCL17,CCL11,CXCR4,GNG3,FGR,CCL5,CCR3,CCL4L1,PRKACB,GSK3A,CCR7,HRAS,SRC,NFKBIA,CCL19,ROCK2,GNG13,RAP1A,GNB4,CXCL1,CXCL10,CCL23,ROCK1,CCL2,SOS2,GNG5,PIK3R3,CXCL3,ITK,GNAI2,CCR4,CRKL,CCR2,CCL21,IKBKB,GNB3,NFKBIB,CCL18,JAK2,PLCB2,CX3CR1,AKT1,CXCR1,PIK3R2,GNAI3,CCL28,CXCL13,GNG12,NFKB1,CCL20,GNB1,AKT3,CXCL9,CCL1,ELMO1,CCL24,ADCY2,CCL8,STAT2,MAP2K1,CCR1,RAF1,CCR6,CXCL8,CCL3,ADCY3,GNG7,SHC3,CX3CL1,PIK3CA,CXCL12,RAC2,PRKCB,AKT2,STAT1,GNG11,GNG2,CCR5,TIAM1,SHC1,VAV2,PLCB1,CDC42,CXCL11,KRAS,CXCR6,GNGT2,CCL27,PIK3R1 |
| 4.474e-07 | -14.62 | G1/S DNA Damage Checkpoints | REACTOME pathways | R-HSA-69615 | 67 | 41 | 10285 | 3229 |
PSMB3,PSMA6,PSMD1,PSMB2,PSMA2,PSMB6,PSMB11,PSMC5,PSMA5,PSMB10,PSMA4,PSMD12,CDKN1B,PSMC4,PSMC1,COP1,MDM2,PSMA3,PSMB5,CDKN1A,PSMB1,PSMD3,PSMB7,PSMD4,PCBP4,UBB,CCNA2,UBA52,RPS27A,PSMA1,PSMD14,PSMC3,TP53,PSMD7,PSMB9,SEM1,PSMD6,PSME1,PSMB4,PSMD10,PSME2 |
| 4.474e-07 | -14.62 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4477 | 1415 | 16828 | 4835 |
RAB3B,GRAP,MLF1,ZBTB33,JAK1,BAG2,SERPINB10,MCM8,FBXO42,DLAT,FZD4,DNAJC5,JUP,VRK1,EXT1,PGK1,MMP9,BUB3,CFL2,SNX5,ZYX,ZMYM2,KIT,RS1,LMNA,PHF1,PLP1,RNF41,TMEM74,CTNNBIP1,GNG7,KPNA1,CSNK2A1,AGER,RAB18,IDH2,FKBP14,INSM2,RAB31,ARMCX5,DYRK1A,DRP2,AGK,FBXO32,ANAPC2,TRIM27,COPS2,C1GALT1C1,EIF2AK2,PPP3CA,NME2,FGFR1,SHC1,SCFD1,SATB1,CIB3,PRMT2,ACO1,PCK2,CAMK2G,SRP54,ARHGEF6,RABL2B,FAM199X,HEY2,PCDHB8,ZDHHC14,ADRB1,FRMD8,USP2,CAMK1,SNX2,NSA2,TRIM21,ARMCX2,RMND5B,NOVA1,SEC63,RBBP7,HECW1,TRIM37,PTTG1,PTPN1,IKBKB,AKT1,FGD2,L1CAM,HRAS,RAB11A,ASMT,TRIM8,DKK3,CNP,TFG,RND3,CDK8,PFDN5,COX10,MDM2,MRPL13,WDR83,SOCS5,AK2,RPS4X,SOX3,RSPH1,ZDHHC15,MAP3K12,E2F6,ZMPSTE24,FBP2,CD99L2,POGK,PRIM2,TRIM32,NFE2,RNF141,ALKBH2,KLK9,ARHGAP1,DOK4,NCKIPSD,LIG3,PRKCQ,IKZF2,PGM1,TRIM3,APOBEC3A,ID4,PPP5C,XAGE5,LDLR,FOXP3,CCR6,CLU,ANAPC11,LMO4,RASGEF1C,MAD2L1,CDK5R1,MAP2K6,ASB8,INPP5E,CDC16,LTBR,GNB1,CASK,IRF1,CUL2,PYCARD,SLC6A8,TRIM23,ARMCX1,UBE2A,GHR,CCT2,UBE2D3,CXCL11,MED9,SOCS4,PPP1R2,MRPL50,SLC30A5,KLK3,SMARCD3,SFN,RAG1,ENY2,RING1,DHRS4,GNAI3,TRIM46,DNAJC1,HCLS1,SWAP70,MYL12A,ITK,GPAA1,JAKMIP1,TIAM1,TRIM63,SENP5,CTNNBL1,IDH3B,NCOA5,RUVBL2,IGF2BP1,SIKE1,SNX3,USP46,SMAD2,PITPNB,NONO,POLL,GNAQ,SPRED1,RAD1,NFE2L2,ETV6,RABIF,SIRT7,TRAF7,CDC5L,DUOXA2,MTMR12,RAP2B,TNFAIP3,CTNNB1,UBE2N,RAB8B,SOCS2,FKBP4,PSKH1,SMURF1,P2RY10,SLC38A2,DCAF5,TAF2,CDK6,SGMS2,NCSTN,CBX7,USP38,USP39,CERK,NAB1,IL5,LSM6,PEBP1,PROX1,PRKX,FGF13,CX3CL1,ITM2A,ADH1A,BMPR1A,ARHGAP21,RHCG,MCM6,KLF10,DIRAS1,CCND1,SASH3,CASP4,FBXO9,COX7A1,SPOP,NR0B1,BCL2L1,DCAF8L2,ANP32B,ACVR1,IFT57,PPP1CC,NFYA,DUSP1,BATF,RAB3C,MTAP,TNFRSF9,DMAP1,CXCL9,RBPJ,DUSP9,AKR1A1,BPGM,CDKN3,EGLN2,RNF152,NUP107,DEK,PRKD3,POU1F1,CYC1,SLC35A2,NKRF,MCPH1,ID1,RGS10,KIF2A,INPPL1,ASB1,FBXL3,APOBEC3C,POU3F4,XPO5,RNF103,IDH3A,RFC5,THRAP3,MED13L,NSDHL,XPO1,EXOC2,FATE1,HECTD3,DNAL4,HDAC5,UBL4A,GSK3A,GAPDH,LDHA,VAC14,YES1,FAM3A,NEK9,TNFSF10,FURIN,CDK5RAP3,AGAP2,FBXO3,UBE2B,CSE1L,NEK7,PICK1,NTRK3,PHKG1,TSSK1B,CIRBP,SAP30L,RNF146,POLD2,KDM2A,SUMO1,LHFPL1,HSPB1,DCLRE1C,HADHA,RAB4A,DHX16,SERPINH1,PIK3R1,HSPE1,TSPAN7,SNAI3,MAPRE2,EPHA2,NLE1,SRSF1,ITGA2,COX6B1,APH1A,XPOT,CXCL1,WWP2,RABAC1,RAP1A,FBXO30,RASGRP2,ST13,MMP14,RAB6B,RAB28,MDH1,ELK1,MRAS,CXCR1,NEDD8,COPS4,KCNK17,LMBR1L,CBL,GAS8,CDKL2,RAB9B,INPP4A,FKBP10,FGF12,EZH2,LAMTOR3,STAT6,SNX24,TP53INP2,STK11,TESK2,DYRK1B,WIF1,RPS27L,WDR44,MEF2C,CTNNA1,RAB2A,CCNF,LITAF,ARL4A,BAP1,RPRM,FUT1,PHKA1,FBXO25,SCYL2,RAB37,DET1,WEE2,PCDH19,RNF14,PNP,RAB5C,STK38,PRRG1,DNAJC10,RAF1,RAP2C,SMAD3,PPP2R1A,DDX5,EIF4A3,IL6ST,CYTH1,UBE2F,FOXP2,TIMP1,RAB1B,RGS5,SNIP1,UBE2D1,LDHAL6B,TNFRSF14,RBMX2,PPFIA3,CLIC2,NLRP1,FBP1,SLITRK2,CDKN1A,RP2,FOXN2,KDSR,DNAJC27,CRKL,SOS2,PPM1G,E2F4,TOPBP1,G2E3,TRIM11,PROM1,PCGF3,TCEAL7,MAX,RHOB,CAB39,KLK5,DDX4,GNAI2,MRGPRX2,TOP3B,CBX5,RERG,BNIP3L,CXCL14,ADAMTS1,RRAS2,PPP1R16A,COPS7A,DDX42,RNF20,NUP153,OTUD6A,HDAC6,RNF39,ANAPC13,PAFAH1B2,CXCR4,HSPA14,PGR,RAN,TSC22D3,USP14,CXCR6,GNA14,ZMYM4,BTG1,SERPINA5,BICD2,ASB3,RNF122,TMEM164,APLN,MMADHC,NUS1,PLEKHA8,YWHAB,PPP1CB,NFYB,RABL3,UPF3B,ZCCHC12,KLHL15,DAPK1,PDE1A,SESN2,UTP23,RNASEL,RNF26,RAB13,GNG3,CDK5,RAB33A,TOB2,RNF167,TNFSF18,RAB23,PPFIBP1,PTGER1,SUMO3,OPHN1,OGG1,CCR3,PKIG,JUN,RHOJ,CBLN4,WWP1,FANCG,PAX6,STAT1,ZNF507,RPN1,PPID,RAB14,RIOK2,RPL26,TMCC1,DYRK2,FOS,EGLN3,DYNLT3,TMEM31,MAFG,F10,NEK2,NFKB1,PC,PRKAG1,RAB5A,HNRNPK,APOBEC3D,GNG5,DSTYK,CCR2,HMG20A,IPO8,HSP90AB1,POLE4,GPHN,SFRP4,CSRNP1,PADI2,SYP,ATG4A,FUNDC2,ARHGAP25,DNAJC22,BCL7B,SERPINI1,PPM1D,IDO1,CXCL12,F9,PGPEP1,TNFSF13,TOP1,APOO,SNX17,ICAM3,RAB3D,RUVBL1,GIT2,NKIRAS1,KDM4B,RAB33B,CDC42EP3,MCM3,TRIM54,RCE1,RASGRP3,RGS19,LDOC1,PDCD4,CREBBP,FAM162A,CCNB1,AKAP14,CHRDL1,NLRP6,METTL2A,PTGER4,TRAF3IP2,UHMK1,ERH,PIP5K1A,MAP3K11,GTF2H2,PIK3R3,MORC4,TERT,GNG2,RASL10A,IDH1,SAT1,GNG13,SRC,FOLR2,PTPN22,SOCS3,PGAM1,LRP6,RNF121,STK24,NFKBIB,MMP21,RAC2,PRKAB1,GNB4,CNTN1,ACTB,PAX9,CSNK1A1L,LNX2,SOX2,SNX18,RFC2,DERL1,KLK6,DNAJC3,SERINC3,TAS1R2,TSN,STAU1,PLA2G12A,BRCA1,RAB30,TRAF2,CDK4,NPR2,PFDN4,RGS2,DUSP19,NME1,PPP4C,PDHA1,BCL10,NOS1AP,DNAJB2,TRIM24,ACSL4,CIB2,EED,LGR4,HSCB,TFEB,PPP1R12A,EWSR1,VMP1,HSPA8,SSRP1,BECN1,LMNB1,MED21,DNTT,OSBP,GOLGA5,SMC4,RAB22A,UBE2V2,AK5,ITGA6,CSNK1A1,UBE2M,PIR,TRIM10,TFE3,UBE2E3,MOSPD1,RNF113A,EFNB1,FCHSD2,NUP37,TRIM5,EIF4E,COX4I2,CDKN2C,ITGAV,MXI1,USP5,FOXP4,RNF126,LDHB,DDX39A,IGBP1,AKAP12,SMARCA5,DRAM1,BAK1,ELK4,CD274,FAIM,PPP2R3A,FZR1,SMAD4,RNF8,PEA15,FXN,UPRT,EP300,MECR,ADAMTS10,UBE2G2,COPS5,TRIM26,STAT5A,MAGEH1,OTX2,EIF4A2,FEZ1,PLCB2,MAP2K1,APOBEC3F,CYTH4,PTP4A2,FAM3C,PTPN4,VEZT,RIT1,TPM3,SNRPB,AR,ADCK1,SLC25A5,NLRP9,WSB1,TOPORS,LYZ,LAMP2,TANK,TNFRSF1B,MPG,TGFBR2,DMPK,USP3,CDC23,GNGT2,OR5M9,RABGGTB,NKAP,FBXO7,RPL23,SPIN3,KCTD3,VAMP7,CTTN,RASL12,SMAD1,GABPA,FKBP8,PPP2CB,RRAGB,CCR7,TTL,PPP3R2,TIMP3,GMPS,SIAH2,CER1,BIRC2,MTM1,FCGR2B,SUCLG2,DUSP3,SCML1,UMPS,TYMS,SS18,RUNX1,GJC1,IGF1R,CX3CR1,ARHGAP12,UBP1,DIRAS2,ORC6,DROSHA,STARD4,THOC2,EDA2R,FKBP1B,LMO2,FAM177A1,PSEN1,MAGEC2,MCM4,MDC1,SP1,MGMT,TRAM1,TADA3,FUNDC1,ASB7,PRKACB,FEN1,IMPA2,SPRY1,CNOT2,MYBL2,PLEKHO1,ERAS,TKTL1,SCML2,DNAJC19,ELF5,TRAF6,ROCK2,KRIT1,RNF10,POLE3,NFKBIA,PREB,NCAPG2,ETF1,PPP1R11,KLF4,DENND2D,COPS7B,MSH6,RAP2A,RNF34,RFC3,GPM6B,IP6K1,FBXO22,FBXW4,P2RY4,HLF,SERPINC1,RPL10,FBXL4,PTPN11,NOTCH2,CCR1,DTWD1,RPA2,ASTN1,TP53INP1,TRAF3IP3,FAF1,TAB2,SRPK2,ARFGEF1,TLR8,CD40,SLC6A2,TNFSF15,PLAC1,SIN3A,CDK7,TCEAL1,RAB6A,USP16,RGN,FKBPL,ZNF428,TNFSF8,GADD45A,GRPR,BTG3,PIGA,RNF148,PPP1R1A,MSTN,SPSB3,DDR1,TOR1B,SAP18,PIAS1,PNPLA4,POLA2,POLB,CCNH,EIF1AX,HSPD1,GNA11,HSPA5,SERPINB1,SRSF2,HSPB6,SNRK,WDR45,NKIRAS2,ACVR1C,PQBP1,GPRASP2,PIP4K2C,STUB1,PPP2R2C,STK4,TNKS,SLC22A17,PLS3,TRIM44,GNB3,HINFP,VAV2,ITGB8,BTG2,COX8A,HUWE1,USP8,CPLX2,PTK7,FTSJ1,DHX38,PGRMC1,RAB39B,CSNK1G3,UBE2L3,PMAIP1,TCEAL8,BCL7C,NINJ1,FBXW11,RGL2,ITGB5,PPFIA2,TRIM34,RB1,TRIM29,PNMA3,DKC1,ZBED1,FBXO44,PLD3,NDUFA1,HFE,MCL1,GSTA2,NT5DC1,TRIM36,NDUFS6,JAK2,DDX23,PCNA,PIK3R2,SPRED2,DCAF12L2,FZD3,RHOBTB1,PTP4A3,HSPB2,NXT2,STK3,TNKS2,GNAZ,PLCB1,DNAJB9,RNF144B,SPP1,NTRK2,GNG12,APOBEC3G,TSR2,OR10A4,USP15,FBXW7,CDK12,ARL4D,CITED1,PSMD10,TNNI3K,EPHA4,CXCL13,RORB,CKS2,CCDC160,SDHB,PCGF6,MAGEB10,CXCR3,UAP1,CCNA2,MAGED2,RLIM,PTEN,SURF2,TNR,BOK,YWHAZ,ICAM2,NLRP3,CBX3,RASD1,RND2,PPP1R1B,BMPR2,BCL9,HSD17B10,IER2,SNX10,ZMYM3,USP6NL,HERC4,DKK1,RRM1,RBM22,KRAS,BCL6,BAG3,OXSR1,ORC5,DLST,TMEM185A,PIK3CA,CDH11,CHIC2,TMEM47,FBXL19,AP1S2,APEX2,SUFU,SF3B1,DAPK3,COCH,RAPGEF5,PICALM,COX6C,NUF2,CRTC2,BAX,UBE2E2,RPS6KA4,RHOBTB3,DDX46,OCRL,ELK3,DPH3,CD81,GRAP2,RAB27A,COX6B2,RNF133,PRKCE,TSPAN17,FBXL14,RHEB,SESTD1,PPP2R5E,SH2D1A,FOXA3,PARP2,NF2,HSPA13,DAAM1,SERPINA1,SUMO2,CCR4,KLF3,TNF,FBXO8,ST6GAL1,CDC7,TRIM45,SRSF7,DUSP21,SAV1,STAT2,CBLL1,RBBP8,UBA3,SGMS1,TIMP4,XRCC5,GNAO1,CDC20,SNX22,IL2,NBN,TBC1D25,IRAK4,WDR11,NHEJ1,CCND3,RAB11B,ARL6,SNX12,IRF4,CMTM7,NEURL2,PLP2,RNF139,NUP62,NDP,SMG5,USP13,FGF3,RAB9A,IL7,SRSF4,TNPO2,SH3BGRL,APPBP2,SMAD9,PTPN5,FOXJ3,USP30,JUNB,RAD23B,VCPIP1,RPS3,TCEA1,BCAS4,CHN2,DDIT3,SHC3,CDC26,DDIT4,SMYD3,STK38L,PIGC,RAB3A,CTNND1,KPNA2,CKS1B,AUH,TFRC,RGL1,SUV39H1,HMGA1,PRKCB,PABPC5,FOXI3,RBM41,LCP1,PCYT1B,GJB1,SKP1,DNAJC7,ADAMTS20,HDAC11,DUSP22,PLCL1,YWHAH,DIRAS3,CDK17,ATP6V1D,CDKN2D,BCL2A1,TFDP2,SUPT4H1,VPS39,ZNF189,PTPRZ1,EEF1B2,MPP1,RANBP10,BMPR1B,TULP3,MLH3,FBXO11,PCBP4,SPSB1,APOBEC3B,RBBP9,WNT10B,FOXC2,RAB32,PITPNA,ASB11,RGS1,SDHC,RHOG,FAM83A,COX7B,IRF8,KPNA6,TOX,TP53,DUSP18,SMUG1,KIN,ASCC1,CXCL10,SENP8,GPC4,FOXD3,FBLN5,TRIM35,PPM1B,PML,DNASE1L1,ARF4,SERTAD1,ARF1,GNG11,HMGB1,DUSP6,PDCD5,ARF6,FBXL7,LBR,FGR,SPHK2,RCHY1,RPRD1B,CXXC1,STYK1,MAP2K3,DOK5,TFPT,RIT2,ALOX5AP,PRDX4,SLC25A14,NUP35,MECP2,ZC4H2,CETN2,CBFB,RGS6,SMARCE1,ENO1,UBE3A,CHST7,SERPIND1,ORAI2,TNIK,PPP2R5A,TLR7,SAP30,POU5F1,MSN,FGF16,PTGES,MAGEB1,DICER1,RNF128,SYBU,SERPINB6,FTHL17,RALA,G6PD,ADK,MID1IP1,BRMS1L,UBE2I,MXD1,MFAP1,HCST,FBXO34,ZBTB16,EZH1,CAPG,RNF7,SAR1B,CCR5,MAP3K3,RNF11,CYTH2,RPL22,WDR82,DLG3,RHOU,ACSS2,DNAJC2,GNB1L,ATF3,RANBP1,MET,FZD6,CRADD,PPP1R3C,HELT,SERPINB9,UBE2V1,S1PR4,SNX11,GMNN,RALB,FKBP2,CCDC22,RNF40,KDM1A,DDX1,TP53I3,SNRPA1,ABHD2,BIRC5,FGF23,RANBP6,LDB1,SFRP1,ELF1,PNMA5,ENO2,PSENEN,UBE2H,CAMKV,ARL5B,VPS26A,HERC3,EEF1E1,PTGER2,MYC,CD40LG,RAB35,MAB21L1,BRS3,PPP1R8,ZMAT3,TRAF1,SERPINA3,RASSF4,CLK1,GEMIN8,MYL6,PRPS1,GPR173,TOP2B,BAD,VAPB,PDCD10,AKAP1,PSMA6,HMGN4,NLGN1,COX7B2,CDKN1B,TRIM62,SYK,VPS16,ACO2,CDC42,AHSA1,PLEKHF1,DUSP10,STRADB,SIAH1,NCK1,IL2RG,SNX1,PSEN2,FBXO31,PIGK,EEF1A1,GAS2,AMELX,GLO1,PRKCA,RAB1A,PDCD1LG2,BRD3,TESK1,DVL2,TTC33,RPL39,ALDH1A3,CLIC4,ANKRD10,HNRNPH2,SMARCB1,MMP20,ENC1,PLCXD3,TRIM6,PYGB,FOXP1,SLC4A10,RFC4,COTL1,FKBP1A,APEX1,GAB1,AKT2,RNF5,CHMP2B,PAK6,GRB10,CSNK1E,AKT3,POLD4,BCKDK,DNAJC4,ARMCX3,NAP1L3,CUL3,ARHGAP19,FAS,ATF1,ERCC3,COX6A2,XBP1,MAD2L2,RBBP4,GPR34,RAP1B,AKAP17A,RAD21,DNAJB4,AIFM1,SNX14,TIMM8A,EGR1,ACVR1B,ARHGAP15,ANAPC4,RHOH,UBE2S,LRRC4B,PIK3CG,COX4I1,MAGEA4,HDAC3,RBM3,GLRA2,RACGAP1,CORO1C |
| 4.481e-07 | -14.62 | SLC4A7 (solute carrier family 4 member 7) | protein interactions | 9497 | 175 | 80 | 19454 | 5460 |
FLOT1,RPL28,PHF1,RAB3B,KRAS,COX8A,NTRK2,EGFL8,TMT1A,MOB3C,SLC4A8,RND3,NHERF1,RAB4A,RPN1,IZUMO1,UBR7,GDE1,CLEC2B,DNAJC25,CHRM3,KBTBD4,CAV1,STX6,DIRAS3,LMAN1,RHOH,ARF6,CX3CL1,DNAJC1,RPL35A,RAC2,HSD17B11,GJA1,RAB35,HRAS,PTPN1,YWHAB,STYK1,MSMB,RHOG,YWHAG,YWHAH,LAMP3,RAB5C,LAMP2,STX7,EMC1,DERL1,RAB9A,RAB5A,RHOU,SSR1,ST7,CFTR,CDC42,SEC62,RND2,OTULINL,BET1,CLDN4,APEX1,VIRMA,LGALS3,RHOJ,SEC61B,TMEM74,DLG4,TNFRSF1B,PSMG3,NTRK3,YWHAZ,RHOB,LGALS8,LAMTOR1,DNAJC5,RAB11A,CIAO1,SFN,RAB2A |
| 4.509e-07 | -14.61 | NMI (N-myc and STAT interactor) | protein interactions | 9111 | 116 | 58 | 19454 | 5460 |
PSMA1,CNOT7,LSM4,HNRNPK,TOLLIP,AP1M1,TRIM21,MAD2L1BP,GFM2,SMARCB1,HGS,APEH,SNAPC5,NECAP2,HNRNPL,COPS7B,LCA5L,SPTAN1,DSTN,RB1,SMCHD1,VPS26A,API5,KDM1A,IRF7,CNKSR3,HSPA8,EXOSC4,DCTN3,LMNA,SH3GLB2,STAT6,MTMR6,ASRGL1,H1-5,CNP,STAT5A,THAP8,STAT1,ACTB,GGPS1,NMI,SNRPD1,UBE2I,MCPH1,CKB,H1-10,BRCA1,LMNB1,PSMG3,EMILIN1,MYC,C9orf72,IFI35,CDKN2D,MORF4L1,BRMS1,MCM4 |
| 4.558e-07 | -14.60 | rRNA binding | molecular function | GO:0019843 | 65 | 39 | 18094 | 5411 |
RBM34,TACO1,FASTKD5,MRPS18A,UTP23,MRPS17,NGRN,RPL12,NOP53,RPS9,NOL12,RNASEL,RPF2,RPS13,RPL8,MRPL18,RPS3,MRPS7,MRPS18C,CIRBP,PPAN,RPS4X,RPL9,EMG1,RPL23A,RPS5,TST,MRPL11,RPLP0,RPF1,MDM2,IMP3,UTP25,RPL23,MRPL20,MRPL16,IMP4,RPS11,BRIX1 |
| 4.584e-07 | -14.60 | CDK-mediated phosphorylation and removal of Cdc6 | REACTOME pathways | R-HSA-69017 | 52 | 34 | 10285 | 3229 |
PSMC4,PSMC1,PSMD12,PSMA3,PSMB5,PSMB1,PSMB7,PSMD3,PSMA6,PSMB3,PSMB2,PSMD1,PSMA2,PSMB6,PSMB10,PSMA5,PSMB11,PSMC5,PSMA4,PSMD7,SEM1,PSMB9,PSME1,PSMB4,PSMD6,PSMD10,PSME2,PSMD4,UBB,RPS27A,UBA52,PSMA1,PSMC3,PSMD14 |
| 4.591e-07 | -14.59 | SERBP1 (SERPINE1 mRNA binding protein 1) | protein interactions | 26135 | 580 | 217 | 19454 | 5460 |
PRRC2A,RPL7L1,MRPL23,SEC61B,RPL37A,UBE2S,TRMT6,FAU,ARMT1,FYTTD1,GALE,RPS29,RIOK2,CUL3,G3BP2,NOP53,YTHDF1,RNF10,EMG1,CCDC86,TERT,UPF3B,LARP4B,APOBEC3C,VAV2,EHD1,WDR77,ZNF593,MAP1LC3A,MRTO4,PHB1,DNM2,AHSA1,MRPS26,TRIM37,DHX16,G3BP1,TNF,RPS24,UBE3A,ZC3H7A,MORC2,GTPBP1,RPS11,CHMP4C,OTUD6B,RAF1,RBM12,B3GNT2,VIRMA,SEC63,DYNLT3,NDN,RAB14,RPS20,METAP2,CYRIB,CCNF,VAMP3,ATP5F1A,FBXO7,NHP2,PIAS1,FBXW7,RPL4,NF2,MRPL17,MTDH,SIRT7,RPA3,SH3GLB2,GRM2,PICALM,METTL14,MRPS34,UBLCP1,CDK7,PIP5K1A,RPS14,ATG16L1,ZBTB2,CDK9,LDLR,KRR1,EIF4E2,PTPN1,HDAC6,SPATS2L,MOV10,MICB,MDC1,VTA1,FBXO25,RNF20,MRPL22,VRK1,CTNNBL1,HUWE1,HSD17B10,HAPSTR1,CPNE2,FAF1,NSDHL,SRP72,TOPORS,YTHDF2,FBP1,RPL10,ESR2,TRIM29,GTF2F1,GTF2F2,CMTR1,NSA2,RPS26,FTSJ3,MRPS25,PSMD14,BTF3,TBCE,SFN,MYC,MRPS7,STAU1,UFL1,FXR2,STK26,PIH1D1,CSNK1A1,GAMT,EIF4B,NUFIP2,MAP2K1,DYNC1I2,DBR1,ECHDC1,RPS10,FAHD1,DUSP6,FUBP3,RPRD1A,DRG1,AGR2,CTNNB1,DDRGK1,MRPL9,PPFIBP1,WWP2,RIOX2,IFI16,CNOT2,PICK1,PABPC1,RPS23,FAM136A,SMNDC1,CAAP1,PDHA1,TNPO2,KIF2A,HPCAL1,MSX2,SOX2,ISG15,UBA3,CSTF3,RPS3,PSPC1,UBE2H,SNX5,IGF2BP1,RC3H2,BICD2,VAMP5,RPL7A,PTPN11,RNF113A,TRIM3,BAP1,RAG1,HEXIM1,UTP15,UBE2M,PRKCA,TFB1M,IDH2,RPA2,RPRD1B,MRPL10,SURF6,DKC1,RBM42,MBD5,RPS16,CAND1,FZR1,MRPS9,SYNCRIP,MAP4,SNRNP70,EDC3,GAPDH,CD81,TMA16,CSNK2A1,ENY2,RDH11,MEPCE,CSE1L,NEDD8,NAE1,MAP1B,RNF8,HBP1,DNAJC2,TP53,FAM162A |
| 4.631e-07 | -14.59 | IFITM1 (interferon induced transmembrane protein 1) | protein interactions | 8519 | 353 | 142 | 19454 | 5460 |
SNX12,SMAP2,SCAMP2,LIG3,PELP1,SRC,YES1,SNX3,TMOD3,RACGAP1,GORASP2,SLC25A1,C9orf72,CALU,AP2A1,NAPA,DLAT,RAB9A,RTN4,SQSTM1,VIPR1,SNX11,BANF1,RPA3,PIP4P1,CHMP2B,USP8,YKT6,AIF1L,NTPCR,CNP,ARHGAP1,STAMBP,PICALM,BORCS5,SDCBP,RPA2,TRAPPC3,SEC23A,CDCA3,EHBP1,CAMLG,TRAPPC6B,FUNDC2,MIOS,GLO1,CD81,LAMTOR2,KARS1,CALR,ATP6V1D,TRAPPC4,LPAR2,SLC25A11,PSME1,STX8,VPS16,PTGES3,TOM1,TOLLIP,TP53,MRPL11,YTHDF2,GFOD2,GNAI3,VAC14,ACTR2,ADAMTS1,ARPC3,NHERF1,TFRC,AP2M1,VDAC2,GNG12,GNB1,BORCS7,LAMTOR3,ACTB,PSMD4,MB21D2,RAB11A,CUL2,FMC1,MYO6,LAMTOR1,HADHA,TMEM106B,ATPAF2,DDX39B,HIRA,STX7,YTHDF1,FXR2,TOM1L2,BORCS6,PGRMC1,EFHD1,TOMM22,RRAGA,MTMR6,CSNK1A1,ATP6V1A,SPINT2,CORO1C,TSG101,MAGED2,LANCL1,TMEM170A,VAMP7,AGK,GFOD1,EIF2S1,OCRL,WDR11,SLC38A9,LRRC57,BAG2,MYO1B,NDUFA4,OSTM1,TMEM87A,TFG,RAB18,HS2ST1,VAMP8,VDAC1,ERLIN2,TMEM59,SNAPIN,PCDH19,ACTN4,E2F4,TRMT1L,PLD3,CRKL,GNAZ,AP2S1,HGS,STX12,PDHA1,VPS33A,VAMP2 |
| 4.635e-07 | -14.58 | MRPL17 (mitochondrial ribosomal protein L17) | protein interactions | 63875 | 156 | 73 | 19454 | 5460 |
MTRF1,GRSF1,ATG7,MRPL9,SNRNP70,CHCHD1,TMEM70,RHOG,MRPL18,ARMC8,MRPS26,POU5F1,SSBP1,GATD3,PRR3,MRPL50,FZR1,UBTD2,MALSU1,MRPL11,MRPL47,METTL15,APOBEC3D,AURKAIP1,DUSP1,MRPL51,RPL18,MRPL49,RPS23,ILF2,GFM2,MRPL52,SRSF7,RPL23A,HINT2,KRAS,HNRNPF,IMMP2L,RPL17,MRPL22,PMPCA,AUH,MYC,MTG2,TUFM,MRPS25,UBE2H,MTG1,MRPL53,TACO1,MRPL13,RPS9,POLR3B,RPL35,RPL13A,MRPL23,MAD2L2,RPL19,RPL10,MPV17,MRPL12,RBMS2,MRPL10,MRPS18A,MTRES1,SLC25A3,ZNF574,NGRN,GFM1,MIS12,PHB2,MRPL41,NHP2 |
| 4.635e-07 | -14.58 | NLRP7 (NLR family pyrin domain containing 7) | protein interactions | 199713 | 156 | 73 | 19454 | 5460 |
PPP1CB,AGO1,SAP30BP,RPLP0,EIF4B,STAMBP,H2BC11,GSTM2,PEBP1,AZGP1,IL1B,SRSF2,DGCR8,ATP5F1A,RPL26,PPP1CC,PCCB,CPSF2,HNRNPAB,RPL7A,HNRNPC,GCC1,LMNB1,CHTOP,CALML5,RPL37A,PSPC1,RPS3,ENO1,DLST,EIF4A3,TMSB4X,RPL19,RPL10,PRDX2,LDHA,RPL35,TUBB,DDX39A,RPL29,EEF2,RPS7,RPSA,ILF2,RPL18,NME1,RPL3,RPL23A,DHX9,SRSF7,MORC2,FAF1,HNRNPA2B1,RPL28,RPL17,H2AC6,HNRNPF,ZBTB16,PPIB,RPL6,RBM17,CSTA,DROSHA,HBA1,RPL24,S100A8,WDR82,RPLP2,RPL9,SRSF1,DHX15,RPL35A,RPL7 |
| 4.660e-07 | -14.58 | regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001242 | 189 | 88 | 18204 | 5365 |
RRN3,SOD1,PPIF,SNAI2,BECN1,FIS1,XBP1,MIR17,BAD,PARL,PTPMT1,SYVN1,MIR16-1,KDM1A,NHERF1,BCL2L1,PYCARD,RPL26,CREB3,PLEKHF1,CCAR2,SELENOS,NKX3-1,FBXW7,RPS7,FCGR2B,S100A8,CXCL12,TXNDC12,AKT1,TMBIM6,CLU,NCK1,RPS3,GPX1,TAF9,TRIM32,CTNNB1,MSX1,IL10,BOK,SGMS1,VDAC2,MIR21,NACC2,MCL1,HTRA2,HELLS,NDUFS3,ING2,PMAIP1,MIR195,CDKN2D,PYCR1,TPT1,IVNS1ABP,SIAH1,CAV1,FBXO7,EPO,NFE2L2,ATF4,NONO,HNRNPK,DDIT3,USP15,SRC,MIR132,ENO1,PTPN1,MIR186,ACKR3,MIF,PPIA,MMP9,SOD2,MIR15A,UBB,NUPR1,HSPB1,BAX,MYC,ERP29,FLCN,PRKRA,SERINC3,TP53,MDM2 |
| 4.726e-07 | -14.56 | MRPL27 (mitochondrial ribosomal protein L27) | protein interactions | 51264 | 189 | 85 | 19454 | 5460 |
MTRES1,RPLP0,MRPS18A,MRPL12,RBMS2,MRPL10,GTF2H4,FTL,MRPL20,NHP2,MRPL40,MRPL41,MRPL57,TRA2B,MRPL17,HSCB,GFM1,MRPL34,EXD2,NGRN,UBE2H,ATP1A1,RC3H2,PCCB,TUFM,FBXO7,MRPL16,PMPCA,AUH,MYC,MTG2,RPL10,RPL19,PSMB6,RPL13A,RPL35,MRPL23,RPS9,MRPL13,MTG1,MRPL53,ZNF22,TACO1,MRPL51,RPL18,MRPL49,TAF2,MRPL33,METTL15,AURKAIP1,MRPL11,MRPL47,RIGI,RPL17,MRPL22,H1-6,FHL3,HINT2,MRPL52,HSPD1,MRPS26,RPS2,H2AC4,CHCHD1,TMEM70,RHOG,MRPL18,TRA2A,ACTL6B,HNRNPA1,MRPL9,RPL6,MTRF1,MRPL24,MALSU1,SRSF10,MRPL50,RPL7,FZR1,FAHD1,GATD3,PRR3,THOC2,SSBP1,COQ8A |
| 4.743e-07 | -14.56 | RPS17 (ribosomal protein S17) | protein interactions | 6218 | 277 | 116 | 19454 | 5460 |
RPL6,XPO1,DDRGK1,CTNNB1,DRG1,RPL23,RPL9,RPL8,PHB1,RPLP2,RPLP1,RPS10,B3GNT2,E2F4,SOX2,H1-3,RPS7,EZH2,CHMP4C,RPS11,MTMR2,RPL18,RPS23,RPL31,RPS24,G3BP1,TNF,KRAS,RPS4X,RAD21,MYC,CUL3,BTF3,RPS29,PSKH1,ATG3,RPS5,RPS26,H1-1,RIT1,FAU,CMTR1,RPL37A,RPS9,SEC61B,RPL35,RPL10,RPL19,H1-5,EIF4B,PIH1D1,RPS28,YAF2,UFL1,STAU1,G3BP2,CDC37L1,COPS5,HDAC6,TUBG1,RPL24,SNRNP70,RPS2,RPL12,KRR1,RCHY1,FZR1,CAND1,RPS16,PRNP,PTP4A3,TMPO,RBM42,CDK9,SURF6,ZBTB2,KBTBD4,UBL4A,TP53,RPSA,TFCP2,DNAJC2,SRP72,NUPR1,RPL23A,HUWE1,VRK1,RPS13,PAGR1,MEPCE,PPP1CC,RC3H2,CDC73,UBE2H,RPS3,METAP2,PTEN,RPS20,SMURF1,RPL22,VIRMA,RPS14,FGF13,CFTR,RPA2,RPLP0,HEXIM1,RPL27,BAP1,RPA3,SQSTM1,RNF113A,RPS15,HMGB1,FBXW7,RPL4 |
| 4.760e-07 | -14.56 | KRR1 (KRR1 small subunit processome component homolog) | protein interactions | 11103 | 365 | 146 | 19454 | 5460 |
RPS2,NOL12,TAF9,SNRNP70,H2AC4,MPHOSPH10,SPATS2L,CMSS1,MOV10,CDC5L,ZBTB2,SURF6,RBM42,DKC1,PRNP,CGAS,FZR1,SPPL3,CAND1,RPS16,PRR3,RBM34,LLPH,RPL15,H2AX,APOBEC3D,AURKAIP1,RPSA,IMP3,RPL17,RPS13,SRSF12,MEPCE,IMP4,NOC4L,TGFBR2,PAK1IP1,H3C1,RPL23A,RPL3,NKRF,SNIP1,ELAVL2,ZSCAN25,RPL26,RPS17,RPL7A,SMARCA5,RPF2,RSL24D1,SRPK2,SMURF1,RPL13A,ZNF622,MACROH2A1,FGFBP1,PRKRA,PHAX,RPS3,ZNF770,UTP15,ZNF574,RPLP0,RPL26L1,HEXIM1,GRM2,H2BC11,RPA2,KLF12,RBMS2,RPS14,BRIX1,UTP23,AATF,RPL4,RPS15,MAVS,SIRT7,RPA3,MRPS26,ZCCHC9,WDR12,DDRGK1,NGDN,MRPL9,RPL6,DDX50,IFI16,BAZ1B,SNRPA1,RPL7,RPS10,NOP58,HP1BP3,SRSF1,FBXO32,MRTO4,FABP5,RPS11,EZH2,RPS7,H1-3,SOX2,MAK16,RAF1,RPS27A,SRSF4,RPS4X,GNL1,KRAS,H1-6,RPS24,EWSR1,PPAN,RPL31,NSA2,H1-1,RPS5,H1-10,ZCRB1,FTSJ3,FYTTD1,ZNF668,NOP16,RAB11A,CUL3,MYC,ESR2,RPL10,RPL19,RPL7L1,RPF1,RPL35,RPS9,ZNF189,ZNF22,MAP2K1,BET1,H1-5,MRPS7,STAU1,NOP53,UFL1,CCDC86,EP300,SF3B1 |
| 4.769e-07 | -14.56 | JAK1 (Janus kinase 1) | protein interactions | 3716 | 234 | 101 | 19454 | 5460 |
STAT6,ARL15,CFTR,HCST,CDC42,FBXW7,CLDND1,TICAM2,PML,RHOU,SYVN1,UBE2H,IL2RB,PTPN11,IFNAR1,RHOJ,STAT5A,VIRMA,SMURF1,EIF2AK2,EIF4A3,GAB1,STUB1,SLC1A1,TRIM27,DISC1,IL20RB,TP53,UBL4A,SOCS3,MGARP,TGFBR2,FN3KRP,IL6,SOCS2,CCR5,IGF1R,EID1,EMC4,NFKB1,LAMP3,TOP1,PRNP,SPPL3,MDM2,CD274,SMAD3,AIFM1,CTDSPL2,SYK,IL2RG,RND2,IL6ST,TIRAP,TSHR,SLC15A1,UFL1,JAKMIP1,UPF3B,PEBP1,CXCR4,BRCA1,RHOB,HSP90AA1,MANSC1,STAT2,STAT1,USP16,JAK2,APLNR,PRMT5,GHR,CCR1,RAF1,IFNGR1,LPAR6,ISG15,TNF,KRAS,CD83,OSTM1,S100B,TRIM11,JAK1,EFNB1,PDCD1,AK2,RHOG,MAGOH,CBL,HNRNPD,FAM174A,LAMP2,IFI16,PIK3R1,CISH,P2RY10,HSPB8,SPTAN1,RHOH,CX3CL1 |
| 4.796e-07 | -14.55 | UFD1 (ubiquitin recognition factor in ER associated degradation 1) | protein interactions | 7353 | 148 | 70 | 19454 | 5460 |
CFL1,MYC,USP13,PAPOLA,PDCD4,MAPRE1,GZMK,SPCS3,ETNK2,ANAPC2,CCNF,NFKBIA,CLRN2,LDHA,CD2AP,TPT1,UBAC2,EP300,UNC45A,TMUB1,FBXW7,HMGB1,NSFL1C,ADRB2,PPIB,MOV10,ATG9A,UBXN6,MTMR12,SELENOS,VCPIP1,HSPB1,DEGS1,UBXN10,AGR2,PSMD7,UBE2N,ARMC1,CHMP2A,DHX15,CAV1,DCUN1D1,SNX1,SVIP,SUMO3,FAF2,ISG15,ERLIN2,DPH5,UBL4A,TRMT1L,KBTBD4,ADORA1,TP53,BIRC5,EZH2,PLS3,TMEM31,PIK3CA,KDELR1,RTCB,UBE3A,FAF1,GLUL,SACM1L,IMMP2L,SEM1,NEDD8,HUWE1,TGFBR2 |
| 4.809e-07 | -14.55 | ZC3H11A (zinc finger CCCH-type containing 11A) | protein interactions | 9877 | 203 | 90 | 19454 | 5460 |
IER2,LARP4B,PCLAF,ZC3H14,PABPC5,UFL1,HSPA8,SF3B1,NKAPD1,THOC3,SLU7,DDX39B,SNRPA,SERPINH1,ELAVL4,BRCA1,RBM27,CHTOP,FYTTD1,SNRPB,RNF40,CUL3,HNRNPC,MYC,ESR2,SNRPB2,SF3B4,SMARCB1,EZH2,GLE1,PAIP2B,E2F4,TOP3B,SSRP1,NUP42,TRIM37,RTCB,SRSF8,PABPC1,MIR9-2,CTNNB1,TRA2A,DDRGK1,PPIB,SRSF10,MIR9-1,SUMO2,HNRNPL,MIR141,MIR214,THOC2,GRM2,RPA2,RBMS2,SF3A1,ATG16L1,AATF,PFKFB2,SIRT7,PML,RPA3,PPIG,ELAVL2,TXNIP,NONO,SUGP1,VIRMA,SNX3,NDN,EIF2AK2,TNFRSF1B,CCNF,MRPL53,SOD2,PPIF,APOBEC3D,NDUFA2,KIF1C,CDC40,DHX9,PQBP1,SNRNP70,TUBG1,AKAP17A,RBM42,THOC1,TOP1,RPL35A,FZR1,ALYREF |
| 4.854e-07 | -14.54 | cellular response to lipid | biological process | GO:0071396 | 534 | 210 | 18204 | 5365 |
HMGB1,SYK,GNB1,CD40,PTK7,NFKBIL1,NKX3-1,FBP1,TESC,PYCARD,STAP1,STC1,TNF,PTGFR,IL10,ROCK2,H2AZ1,CRHBP,UBE2L3,WNT2,HNRNPD,CX3CR1,PLSCR4,PAQR8,ATP1A1,LY96,PHB1,YES1,CFTR,MIR17,TRAF6,NLRP3,TLR2,FKBP4,CYP1B1,TICAM2,VPS54,PDCD1LG2,XRCC5,CDK4,CXCL10,CCL2,FOS,SPHK2,WBP2,NFKB1,MGARP,PTGES3,TRIP4,UGT1A1,SRC,BRINP2,DAG1,GNG2,HSPA8,PHB2,TFPI,KLF4,PDE4B,MIR140,LEP,INSIG2,TLR4,BRINP1,TAF7,LPAR1,CXCL8,PDCD4,DDX5,CAMP,TSPO,RAN,MLC1,NR2E1,CHMP5,IRAK4,PGR,OPRK1,CXCL13,CYP7A1,CAPN2,FZD4,PTGER4,CCNA2,AKR1C2,ABHD2,AKR1C1,TICAM1,SLC6A4,FGF23,ESR2,MIR182,CEBPE,P2RY4,FAM107A,NFKBIB,PTPN22,AKT1,AIFM1,SPP1,IL1B,DDIT4,ADTRP,CXCL1,HAND2,MTDH,CST11,SELENOS,ITGA2,PLSCR3,NFKBIA,IL1A,MAP2K3,CALR,GJB2,TNFAIP3,GSTP1,VDR,KCNMB1,CXCL11,XBP1,TADA3,MIR20A,CCR5,CD14,PID1,SOX9,PLAA,LITAF,BRINP3,AR,ATP1A2,MSN,OR51E2,JAK2,PHC1,LRP6,MIR187,RAMP3,GSK3A,IRF8,EGLN2,MRC1,HDAC5,ADCY2,PRKCE,BAD,ACACA,YWHAH,ATP5F1A,CD274,LDLR,BCL10,KLF9,LILRB1,ERRFI1,CSF2,IRF3,RXRG,PPARA,CXCL9,RORB,MIR223,MIR185,RNF14,UBE3A,IL12B,FBXO32,EIF4E,PTGER2,SFRP1,CREB1,IGF1R,IL6,CD86,MMP9,BGLAP,PADI2,HTRA2,TNFRSF1B,TLR9,PCK2,PLCB1,GFI1,RWDD1,MYD88,MIR342,ATP1A3,CLDN1,MSX2,CDC73,MIR21,MIR96,MIR146A,CXCL3,ELK1,SMYD3,ADCY3,PAX6,GPBAR1,RBFOX2,USP8,WNT10B,CD36,CD80,MEF2C,RUVBL2,MSTN,EFNA5,LDOC1 |
| 4.855e-07 | -14.54 | SNRPA1 (small nuclear ribonucleoprotein polypeptide A') | protein interactions | 6627 | 280 | 117 | 19454 | 5460 |
ESS2,CD2BP2,TP53,ILF2,SEPTIN7,SNIP1,METTL18,MEPCE,SMN1,SNRPG,CDC40,PSMA5,HUWE1,THRAP3,MOV10,RBM17,SNRNP70,SYNCRIP,SRP14,KRR1,MBD5,CWC15,CDC5L,FZR1,TOP1,SNRNP27,CDK7,SF3A1,SNRPN,HEXIM1,TFIP11,STOM,LSM2,CWF19L1,RPA3,BAP1,DDX46,PRPF4,UTP23,HSPA5,RBM22,DNAJC8,SUGP1,CDC73,UBE2H,RC3H2,PHAX,PTEN,SF3B6,CCNF,GCFC2,PSMA6,SMURF1,SOX2,SF3B5,POLR2D,MOB3C,SNRPE,SMNDC1,CHMP4C,PICK1,SRSF7,HSPD1,HNRNPA2B1,ARGLU1,PSMA2,H1-6,KRAS,XPO1,HNRNPA1,DDRGK1,IFI16,LAMP2,PRPF19,POU5F1,RB1CC1,STAMBPL1,EED,RBM5,PHB1,IFIT2,SRSF1,PSMB5,DHX15,RPS10,SNRPD3,BUD31,TOMM22,PSMB3,ZC3H14,PIH1D1,SF3B1,HSPA8,EP300,DDX5,DDX39B,SLU7,SNRPA,UPF3B,COIL,UFL1,SRSF2,EEF1G,PRPF31,SNRPB,MYC,CUL3,HNRNPC,ICAM1,RPS5,SNRPD2,SF3B4,SNRPD1,RPS9,ESR2,SNRPB2,SNRNP40 |
| 4.902e-07 | -14.53 | regulation of leukocyte proliferation | biological process | GO:0070663 | 268 | 117 | 18204 | 5365 |
BCL6,IL1B,CD40,CD1D,HMGB1,PTPN22,PPP3CA,AGER,PYCARD,TNFSF18,GREM1,MZB1,FCGR2B,STAT6,IL1A,SLC39A10,XCL1,IL10,TWSG1,IGF1,CD209,VSIR,TFRC,NCK1,RPS3,SELENOK,TNFAIP3,NMBR,FGF10,CTNNB1,GPAM,GSTP1,TRAF6,KIT,NDFIP1,CD38,PDCD1LG2,CTLA4,DLG1,SFTPD,CCL19,EFNB1,AIF1,CCR2,IL2,TGFBR2,BST2,CDKN1A,TIRAP,PLA2G5,BCL2L1,IL5,TNFRSF14,IL2RA,JAK2,ARG2,FOXP3,IL12A,CD274,DHPS,LILRB1,SASH3,IL18,RAC2,PNP,MIF,PELI1,TNFSF8,TLR4,CD40LG,LEP,BTN2A2,CSF2,PRNP,IL6ST,CCL8,SOS2,MIR185,IDO1,ST6GAL1,SLC7A1,IL12B,CCL5,SDC4,CD86,IL13,IL6,IL21,TACR1,GPNMB,PRKCQ,MYD88,IRF1,IL4,LST1,TLR9,TNFRSF1B,IL20RB,MIR30B,TNFRSF9,MIR21,LILRB4,CD81,CD46,MIR181C,IL34,LGALS3,TYROBP,TICAM1,EPO,IL15,IL7,MEF2C,CHRNB2,IL23A,CD80,CD28 |
| 4.933e-07 | -14.52 | ATXN2L (ataxin 2 like) | protein interactions | 11273 | 257 | 109 | 19454 | 5460 |
MCRIP2,DDX5,HADHA,HSPA8,STAU1,G3BP2,MFAP1,NUFIP2,PAPSS2,AP2M1,MIRLET7B,ESR2,MIRLET7D,PAPOLA,SFN,CUL3,MYC,GGH,BTF3,MIR98,BRCA1,MYO6,YWHAZ,MIR363,HNRNPA2B1,PABPC1,FAM76B,ZC3H7A,G3BP1,KRTAP12-4,E2F4,RAF1,B3GNT2,JUN,SOX2,ISG15,MIR7-2,PHB1,BOLL,RPL8,MIR214,WDR82,FAM98A,SLMAP,PEG10,WWP2,NDC80,CTNNB1,YWHAH,YWHAG,MIR31,YWHAB,MIR1-1,RB1CC1,MIR205,SIRT7,RPA3,MIR10B,BAP1,RNF113A,LSM12,MIRLET7I,MIR7-3,MIR34B,CFTR,GRM2,RNF103,RPA2,TOX4,MIR7-1,HEXIM1,MIR21,FBLN5,CTTN,CCNF,PSPC1,RPS20,NDN,PPP1R10,AAMDC,NONO,RC3H2,MECP2,SPOP,UBE2H,SNIP1,ABCE1,RPL23A,MIR16-2,MEPCE,MIRLET7C,YTHDF2,KBTBD4,MIR200C,MIR17,DDX42,NUPR1,TAF2,SMAD3,MIR25,TOP1,MIRLET7G,FZR1,TMPO,CDK9,GMPPB,EDC3,PPIL4,MIR34A |
| 4.942e-07 | -14.52 | ATG7 (autophagy related 7) | protein interactions | 10533 | 395 | 156 | 19454 | 5460 |
ATP6V1D,SMG8,TRAPPC4,BECN1,TRAPPC2L,GAPDH,EDEM1,EI24,CDK9,EIF2B2,CDK6,RPL32,SRP14,RNF181,MRPL33,PPP4C,ACTR2,ARPC3,CBX3,MAP1LC3B,MAP2K3,TBK1,VPS16,DNAAF10,SLC16A1,RPL23A,RAB1A,TRAPPC1,STK11,CCDC22,STXBP6,ATP1B3,NCAPG2,TUFM,GMPS,RHOBTB3,RUNX1,ATP5F1A,FBXO7,CARS1,TRIM32,SMARCA5,VPS39,UBA3,RPL22,CEP97,ROMO1,PTPMT1,WDR45,GTF2A1,POP7,MID1IP1,CTTN,PELP1,SHOC2,RPLP0,PDCL,RARS1,UTP15,SYS1,EIF2B3,WRAP53,GABARAPL2,COMMD3,CCND1,ACBD6,MARS1,GABARAP,DNLZ,GRPEL1,SMC4,TTR,MRPL17,ARPC2,SQSTM1,PRIM2,UGDH,TMEM30A,RB1CC1,PSMD10,PEDS1,RHOG,UTP6,XPO1,MAP1S,ATG9A,HMGA1,UBXN6,HSP90AB1,CHMP2A,TRIR,SNX1,SNX2,KCTD10,HNRNPL,MAP1LC3A,ARHGAP25,PHB1,PPP2CB,SPRED2,CBFB,WDR6,NLRP2,RPS23,RPL18,UCKL1,PGGT1B,GDI2,VPS33A,GABARAPL1,TUBA1A,GCLC,PSMD12,RTCB,GPSM3,RUVBL2,ABCF1,GADD45A,PPAN,RPL31,POLR1B,RCL1,VMP1,RPS5,ATG3,TAFAZZIN,BAG3,RPL39,ATG101,MTG2,NCKAP1,APEX1,MAT2B,GGPS1,TAX1BP1,ATP5F1B,STAT1,AP1G2,RPL37A,FAM91A1,IRF2,FAU,TRMT112,VPS18,MED23,ETF1,SUPT4H1,RPP21,TIMM10,DUSP14,ATP6V1C1,NRBF2,IL1B,EP300,COMMD2,RLIM |
| 4.944e-07 | -14.52 | energy derivation by oxidation of organic compounds | biological process | GO:0015980 | 257 | 113 | 18204 | 5365 |
CYC1,ATG3,KGD4,PHKA1,UGP2,IDH1,ATP5F1D,NDUFB5,GSK3A,TAFAZZIN,COX8A,PPP1CC,ATP5PF,PID1,NDP,ADRB3,PDHA1,NDUFA2,GYS1,PYGB,SLC25A14,SDHB,VPS54,COX4I1,COX6A2,PPP1R3C,COX4I2,ATP5MG,COQ10B,STBD1,UQCC3,MT3,ATP5PD,ATP5F1B,ETFRF1,AKT1,NDUFA1,UQCR11,SDHAF2,PDHB,ACO1,NDUFA5,SDHAF4,COX5A,ETFB,COX6B2,PPP1CB,GFPT1,NDUFB4,UQCRC2,IDH3B,ATP5F1E,NDUFS3,IREB2,GABARAPL1,UCN,NDUFA4,NDUFS6,COX7B2,OGDHL,SLC25A12,PHKB,NDUFC2,SDHC,SLC25A51,ETFA,COX6C,NDUFB8,PPP1R2,COX7A1,FXN,UQCRQ,PHKG1,ATP5PO,MDH1,GBE1,PYGM,NDUFS2,IDH3A,SUCLG2,UQCRH,TP53,IMMP2L,COX7B,STOML2,ATP5PB,LEPR,DLST,SOD2,COX6B1,UQCRC1,NDUFB6,COX10,PPP1R1A,NDUFV2,DLAT,PTGES3,AKT2,NDUFS8,COMT,NDUFAB1,ATP5F1A,RB1CC1,NDUFB10,GPD2,WDR45,IDH2,LEP,IL6ST,NDUFA12,ACO2,GNMT,NDUFB7 |
| 4.956e-07 | -14.52 | EEF1G (eukaryotic translation elongation factor 1 gamma) | protein interactions | 1937 | 401 | 158 | 19454 | 5460 |
ZNF24,FAM20C,KARS1,COPS5,GTF2E1,CXCL13,HDAC6,DNAJC7,FBXO34,CAMLG,EEF1B2,PRNP,FZR1,CAND1,RPS16,CDC5L,PLGRKT,DKC1,MVD,WBP11,MLLT6,EEF1A1,TP53I3,TFCP2,TNFAIP8L1,RNF8,ILF2,MAP1B,FAF1,HSD17B10,THRAP3,CDK2AP2,TRIM63,NEDD8,SEM1,MEPCE,RGL2,CARS1,AKT1,HMOX2,TRIM23,EIF3G,SPOP,MAPRE1,UBE2H,CDC73,TUBA1B,PSPC1,CCNF,GSK3A,COPE,MKKS,NDN,DYRK1A,PDCD5,VIRMA,SMURF1,ATG16L1,CDK7,CFTR,CDC42,METTL14,DRD3,RPA2,UBE2M,HEXIM1,RPL26L1,HNRNPH3,BAP1,RPA3,INPPL1,SOD1,MTDH,CCDC106,RNF113A,FBXW7,NPM3,HSPA5,EID2B,WWP2,DDRGK1,YWHAG,HNRNPA1,AGR2,PPM1B,DDX23,GSTO1,PHB1,FOLR1,RPL8,COPS2,EED,SNRPA1,SUMO2,HMG20A,CCT7,SRSF10,FEN1,RAF1,MSX2,GTF2E2,ISG15,SNAPIN,SOX2,PDHA1,EZH2,MTA2,CRELD1,GADD45A,PABPC1,SRSF7,TRIM21,TRIM37,VDAC1,PTPN4,RBBP7,AHCYL1,GTF3C3,CUL2,CUL3,MYC,PSMD1,SAMHD1,BTF3,PSMD14,YWHAZ,BRCA1,CMTR1,DLG4,DLST,ARF1,GTF2F1,SNRPD2,TUBB,MATR3,PSMD4,ESR2,CBX5,GADD45G,NUDT3,TMC7,PPT1,PIH1D1,MED31,RPS28,MCRIP2,PSMA3,EP300,HDAC5,SAT1,HSPA8,ADRB2,GPC1,EEF1G,STAU1,UCHL3,UFL1,ZDHHC17 |
| 4.963e-07 | -14.52 | PDIA3 (protein disulfide isomerase family A member 3) | protein interactions | 2923 | 410 | 161 | 19454 | 5460 |
DLST,SEC61B,RMDN3,RBBP4,DYNLL1,TAGLN2,SNRPB2,ATP6AP2,PARL,CUL3,MYC,BTF3,DCAF4,CKB,SERPINH1,COP1,TMEM106B,PEBP1,DNAJC3,DDX39B,EP300,AKAP1,TAPBP,HSPA8,ATP5IF1,DNAJC22,PACSIN3,PXMP2,FBXL4,PAFAH1B1,MRPL12,EDEM3,DET1,PRDX3,SEC62,CNPY3,PPT1,PAK2,ATP5PO,ADSS2,PLAA,KLF3,CNDP2,PIH1D1,PSMB5,ANXA4,ATP6V1A,CORO1C,SUMO2,DNAJB9,HSP90AB1,GSTM3,HMBS,ZNF207,CTNNB1,PPIB,AGR2,CDK5RAP3,HSPB1,RPL23,HNRNPA2B1,HSPD1,UBE3A,PDIA6,TRIM37,IFNG,ANP32B,HNRNPDL,ARFGEF1,B3GNT2,RAF1,ANP32A,SOX2,PDHA1,CHMP4C,NGB,PLS3,EZH2,PLD3,ITGB5,ENO1,CCNF,TRIM24,INHA,SEC61A1,CTSB,LDHA,BCCIP,VIRMA,PTPN11,HSPA14,DNAJC5,MTPN,DNAJC10,CALU,UBE2H,BAP1,RPA3,SOD1,ITGA2,ACP5,PGK1,SYVN1,HMGB1,EIF5B,CLU,HSPA5,PIAS1,CAPN1,JMJD8,UBA52,ATG16L1,RBFOX2,CFTR,MND1,METTL14,HSP90B1,IDH2,RPA2,UBE2M,COX4I1,UBE2N,EFNA3,ITGA6,CD274,LDLR,MTAP,SEMA3C,MIF,CAV1,PLGRKT,MDM2,ATP5PD,FAM20C,PGAM1,CALR,DPP4,GAPDH,COPS5,HDAC6,SLC2A1,DNAJC4,BACE1,PSME1,RAB1A,ERO1A,ABCE1,SOS2,HNRNPK,DNAJC30,CD1B,TOLLIP,CSE1L,HSPE1,MRPL47,RRM1,MAP1LC3B,NHERF1,HSPA13,RAD23B,PPME1 |
| 5.036e-07 | -14.50 | DAP3 (death associated protein 3) | protein interactions | 7818 | 321 | 131 | 19454 | 5460 |
SOX2,CHMP4C,HINT2,SRSF7,MRPS11,HSPD1,LSM14A,RBM3,MRPS17,SRSF4,IMMP2L,HNRNPA1,TRA2A,DDRGK1,MTRF1,MRPS35,STOML2,RPL6,WWP2,MRPS26,HNRNPD,ARMC8,LHX2,RHOG,GATD3,FUBP3,RMND1,HNRNPL,PGR,TIMM29,NGRN,EXD2,RNF11,MRPS7,HSCB,UFL1,NOP53,MTG2,MYC,AUH,PMPCA,PYCR1,CUL3,HSP90AA1,MCAT,FBXW11,MRPS25,RPS9,TACO1,MTG1,CCDC90B,ESR2,RPL19,PRRC2A,RPL10,RPL35,APOBEC3D,DUSP1,AURKAIP1,PPARA,METTL15,MRPL11,GFM2,RNF8,CLPB,HAPSTR1,MRPS18B,FASTKD5,MEPCE,MRPS18C,RIGI,RPL17,DNAJC30,COPS5,E4F1,MOV10,GRSF1,COX5A,DNAJC4,SNRNP70,CHCHD1,TMEM70,PRR3,TRMT10B,SYNCRIP,SRP14,MRPS9,SSBP1,ALYREF,RCHY1,COX4I1,SURF6,MRPS23,ZBTB2,FZR1,CGAS,PRNP,KLF12,RBMS2,CFTR,ZNF574,DYRK2,HEXIM1,MTRES1,KLF4,HAUS2,MRPS34,RPA2,GRM2,SQSTM1,GFM1,BAP1,RPA3,PPM1G,CRYZ,SLC25A51,HMGB1,RPL4,FBXW7,RPL26,AR,TUFM,IGF2BP1,UBE2H,DNAJC19,RC3H2,MRPS28,PTEN,CCNF,EIF4A3,SMURF1 |
| 5.059e-07 | -14.50 | PRPF38A (pre-mRNA processing factor 38A) | protein interactions | 84950 | 159 | 74 | 19454 | 5460 |
SRSF8,SRSF7,FAM76B,SNIP1,MEPCE,RPS13,SRSF4,MYORG,TSSC4,KRAS,RPL29,E2F4,RAF1,H2AJ,TAF2,NUPR1,TMEM14B,PDHA1,DDX42,EED,FOLR1,ZBTB2,PTP4A3,PPIL4,CSNK2A1,TMA16,XPO1,ZCCHC10,IFI16,UQCR11,ANKRD50,SNRNP70,H2BC17,SQSTM1,KIN,CLK1,ACER3,NKAPD1,RPA3,POLA2,PSENEN,SUMO1,MFAP1,NUFIP2,SDCBP,LMNA,RPA2,TOX4,CSNK2B,PRMT5,AP2M1,EZH1,DLST,EIF4A3,CTTN,TACO1,PSPC1,SRPK2,NOPCHAP1,ESR2,UBE2V2,PPP1R10,SPCS1,IFI6,ANAPC15,CFAP20,SEC13,MYC,RIT1,UBE2H,PPIG,PEA15,PIP4K2C,MECP2 |
| 5.072e-07 | -14.49 | LNPK (lunapark, ER junction formation factor) | protein interactions | 80856 | 286 | 119 | 19454 | 5460 |
UBB,SEC63,TMEM74,CDIPT,ATL1,SYP,ATP1B3,PHKA1,HMOX2,DNAJC5,TMEM209,CERS2,YKT6,SLC7A1,LPAR1,MTDH,SPCS2,DERL1,RTN4,RAB9A,RPA3,TEX264,NCDN,PDCL,LEMD3,RPA2,SSR1,USE1,GPR35,CHMP1A,SLC12A2,ST7,TPRA1,RABL3,ARHGAP1,SEC22B,LMAN1,DNAJC1,CAND1,ARL6IP5,HSD17B11,PTPN1,SRPRA,CAMLG,OSBPL8,POR,ESYT1,HM13,EI24,DPP4,TMEM199,SELENOS,SLC25A46,DHRS7,SLC6A8,FKBP8,CD1B,RAB3B,NOC4L,LPAR2,STX18,YIF1A,NSDHL,VAC14,LBR,SLC51A,CCDC47,PREB,ATP6AP2,RANBP6,PHKB,SEC61B,ARF1,LMBR1L,SCFD1,ZMPSTE24,LMNB1,VEZT,CUL3,PXMP2,STX7,UFL1,SYNPR,TMED3,TACR1,RAB5A,ARCN1,VAPB,OTULINL,SEC62,LMO3,PGRMC1,TOR1AIP2,SLMAP,STX5,CYB5A,RAB35,CDK5RAP3,UBE2D1,DDRGK1,PAX6,TFG,RETREG1,EMC8,KRAS,SCD5,TMT1A,RINT1,TAPT1,KLHL12,CYB5B,STIM1,RPN1,RAB4A,DNAJC25,FAF2,NUDCD3,STBD1,MACO1 |
| 5.072e-07 | -14.49 | UBE2D1 (ubiquitin conjugating enzyme E2 D1) | protein interactions | 7321 | 286 | 119 | 19454 | 5460 |
NBN,TRIM3,TRIM10,MYLIP,CDK7,WWP1,RNF103,RNF146,RAG1,HECTD1,DYRK2,RNF122,STUB1,TRIM24,PTEN,UBASH3B,TRAF7,TRIM27,NR1H2,TRIM54,SMURF1,TRIM32,TNFAIP3,FBXO7,BFAR,TRIM23,SPOP,DTL,RNF167,HSD17B10,RING1,TOM1,POLL,TRIM63,RBCK1,ANAPC11,RNF115,HUWE1,RIGI,TRIM62,TAF1D,UBE2B,ZNRF1,RNF8,RNF181,TOPORS,RCHY1,TRIM45,RNF128,SHPRH,MARCHF4,CAND1,FZR1,CDC5L,MDM2,RNF14,KLHL9,HDAC6,MUL1,CRBN,AREL1,FOS,HERC3,PMAIP1,EP300,ARRDC3,RNF10,TRIM22,RLIM,TRIM5,BIRC2,UBE2D3,RNF5,SKP1,RNF11,CDKN1A,RNF182,RNF7,CRYAB,PSMB7,ANXA7,NFKBIA,HECW1,SIAH1,APEX1,UBTD1,CUL3,CUL2,CREBBP,BRMS1,BRCA1,COP1,GADD45A,UBE3A,TRIM11,TRIM21,KCTD17,TRIM37,UFM1,TRIM26,KRAS,PELI1,AHCYL1,RNF26,TRAF2,FAF2,RNF126,IGBP1,TRIM35,TRIM8,MARCHF5,WWP2,SIVA1,CTNNB1,SIAH2,TRAF6,UBE2D1,NQO1,CBL |
| 5.072e-07 | -14.49 | SF1 (splicing factor 1) | protein interactions | 7536 | 286 | 119 | 19454 | 5460 |
CTTN,CAB39,UBE2L3,RSPH1,CIAO1,RUNX1,RC3H2,TRIM23,EXOSC1,RBM7,RPA3,BAP1,IDH3A,PML,HNRNPH2,PGK1,METTL22,SF3A1,WDR83,RBFOX2,CDC42,PRMT2,CFTR,LMNA,RPA2,STOM,HEXIM1,TFIP11,MIR106B,UBE2N,SEC23A,TES,RPL35A,MIRLET7G,CWC15,NFKB1,RBM17,RPL24,KPNA1,MIR34A,FAF1,ZC3H11A,EMC2,HNRNPK,SRPRB,ABHD10,MVD,FBP1,HADH,ARHGAP12,EXOSC8,DISC1,NUPR1,SF3B4,TENT5C,IREB2,SNRPB2,MYC,CUL3,TMED4,HNRNPC,SAMHD1,TOMM40,CIRBP,CCDC25,RIT1,SLU7,DDX39B,SNRPA,XRCC5,SF3B1,HSPA8,HDAC5,EP300,PSMA3,UFL1,STAU1,YTHDF1,RNF41,ACTL6A,WDR77,PLAA,APOBEC3C,CTBP1,MAP2K1,EIF4B,SIN3A,FUBP3,EED,HNRNPL,OSBP,BUD31,SNRPA1,KCTD10,WWP2,MMUT,HNRNPA1,DDRGK1,PDAP1,PLSCR1,HNRNPA2B1,EWSR1,BAG2,FAM168A,HNRNPF,KRAS,TNF,VDAC1,MIR155,UBL5,RAF1,HSDL2,SUPT5H,GFPT1,TNPO2,EZH2,STIM1,VAMP2,PPID |
| 5.133e-07 | -14.48 | regulation of phosphorylation | biological process | GO:0042325 | 994 | 363 | 18204 | 5365 |
CLEC6A,DSTYK,SMYD3,MAD2L2,PAX6,ZNF592,PRKAG1,UCN,CD80,CD36,SMG8,PPP2R5A,RGCC,CREBL2,IFNK,TLR9,MOB3C,EMP2,HDAC3,IFNA2,MIR21,MIR30B,TNIK,INHA,DNAJC3,EHD4,CDKN3,LCP2,SFN,LDB2,FGR,UBE2K,IL12B,YWHAG,MMP9,CD86,IFNA10,GNAQ,ERP29,BAX,MOB3B,IL6,TOM1L1,ROPN1B,ERRFI1,FLOT1,VEGFC,HAX1,SPRY1,PRNP,CLIP3,EEF1A1,FGF1,PKIB,NRP1,LRP6,PTEN,JAK2,TSG101,DEFB114,BAD,CDK5RAP3,DVL2,PRKCE,GSK3A,FAS,KIT,PID1,ODAM,LMO4,MET,SOD1,CARTPT,SLC8A1,DIRAS2,AR,CRKL,CTDSP1,CCND1,CDK12,MIR221,PAK2,IL2,TGFBR2,PIK3R3,IGF1,PDCD10,SPRED1,MT3,CCNI,CCND3,GH1,SLC1A1,BAK1,TXN,HYAL2,GSTP1,AKT1,NOP53,TNFSF15,IL1B,GRB10,SLCO3A1,IFNA13,TLR6,FGF23,MIR137,IL15,CEP85,NF2,UBASH3B,IL23A,SEMA7A,VEGFA,OSM,CCNB1,CAMK1,NBN,MIR218-1,NTRK3,TLR8,NTRK2,TCIM,TAB2,IFNG,NTF4,PIK3CA,DYNLL1,CAMP,MIR15A,CACUL1,PDCD4,ROCK1,SRC,ANGPT1,PTGES3,IL18,RB1CC1,CSH1,PIK3CG,THY1,SQSTM1,LEP,HEXIM1,PHB2,ARL2BP,MAP2K6,NHERF1,DUSP6,HCLS1,CHI3L1,TESK1,PIH1D1,DRD1,RARRES2,CCNF,CAMK2N2,GADD45A,TRAF6,GSKIP,CCNH,TBK1,TRIB1,XRCC5,CCL19,DIRAS1,MIR24-1,WEE2,DUSP22,SERTAD1,TFRC,YES1,DUSP1,LACRT,RAP1A,RALB,CD40,SYK,FGF16,STK11,STAP1,STK38,NKX3-1,FBXW7,PRR5L,HDAC6,MAVS,TAB1,SOCS3,CAV1,IFNB1,EFNA5,CAV3,CDKN2D,AGAP2,HSP90AB1,IL4,NPTN,PKIG,CNKSR3,SOCS5,CD4,HBEGF,PSEN1,MIR146A,LILRB4,IGFBP3,EPHA4,TLR3,MIR106B,CCL5,PPIA,PRDX3,HSPB1,DUSP19,FERMT2,RTRAF,IGF1R,SFRP1,MIR132,BCL10,HTR2A,INPP5K,IL12A,TPD52L1,MIF,PSRC1,CDK5R1,CTDSP2,PARD6A,SOCS4,CSF2,IL6ST,MAP3K12,HSP90AA1,MACROH2A1,RIT2,IL5,TLR7,MMD,FCGR1A,DIRAS3,MAP2K1,HGS,STAT2,SOX9,CBL,RGN,MIR20A,TADA3,DLG3,TGFB2,CHP1,MAP2K3,DUSP3,OSBP,KRAS,DBNDD1,TF,SPRED2,NCK1,FGF10,DKK1,BTBD10,RAP2B,PTPN22,ADTRP,PROX1,TNFSF18,C9orf72,GREM1,ADRB2,CCR7,IL34,IKBKB,CNOT7,EPO,IL7,CHRNA7,EZH2,IL3,GPNMB,MIR711,SESN2,PGR,FAXDC2,RAP2A,CDKN1B,IMPACT,CCNA2,PAQR3,PPARG,MIR212,STK4,TP53,FKBP8,SDCBP,CCNY,TAF7,DIPK2A,LEPR,MIR34A,IL13,KCTD20,ITGA6,IL21,PTPN1,FGF22,GHR,RAP2C,FGFR1,P2RY1,MIR26B,PTPRQ,TLR4,APLNR,TRIM27,DLG4,ZBED3,PTPN11,CDKN1A,ZNF622,PSMD10,TNFRSF14,ADNP,RB1,STRADB,ILK,ACVR1,LDB1,DDR1,CLDN3,F2,CX3CL1,RAF1,ROCK2,FGF3,MAP3K11,DDRGK1,CAMK2N1,ACTB,TNF,ADIPOQ,FGF17,PHB1,RPS3,TRIM6,CDKN2C,TRAF2,CX3CR1,EPHA2,HEXIM2,RGS2,CORO1C,FGF7,DNAJC10,PKIA,AGER,PYCARD,HRAS,DUSP10,BCCIP,CAB39 |
| 5.134e-07 | -14.48 | SLC1A5 (solute carrier family 1 member 5) | protein interactions | 6510 | 240 | 103 | 19454 | 5460 |
ARF6,SPPL3,CAND1,LMAN1,CAV1,HRAS,ACSL4,COQ8A,TES,RAC2,STYK1,DPP4,SLC25A46,FAM20C,LAMP3,SRPRB,RAB3B,PSEN1,MAP1B,SFXN1,TFCP2,SLC25A24,TP53,TRIM6,MTCH2,RHOJ,CD47,DYRK1A,SMAD5,VIRMA,PLP1,VAMP3,CCNF,ALB,RC3H2,ATP1A1,UBE2H,RAB2A,PYCR2,DNAJC5,RHOU,NCDN,PML,RAB9A,RPA2,GRM2,WWP1,ARL15,CDC42,CDK7,HACD2,RHOH,EGLN3,DIRAS3,RAB35,MPDU1,PHB1,GJA1,SDHAF2,RHOG,AGR2,SLC25A28,LAMP2,SYNJ2BP,MRPS35,RAB5C,YWHAH,DDRGK1,EPHA4,KRAS,VDAC1,FLOT1,ZC3H7A,COX8A,RAB4A,RND3,TOP3B,RAF1,LGR4,LGALS3,ALG5,GNB1,ESR2,LMBR1L,CYB5R3,SERINC1,GPR89A,LAMTOR1,RHOB,NTRK3,MYC,RAB11A,CUL3,ADRB2,STX7,PMAIP1,EP300,RAB5A,TBC1D17,CLDN4,RND2,YIPF5,NEK7 |
| 5.151e-07 | -14.48 | CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X) | protein interactions | 10845 | 181 | 82 | 19454 | 5460 |
POLDIP2,HSCB,EP300,GFM1,RAB9A,AMACR,EXD2,ATPAF2,NGRN,MTRES1,PDP2,LMNA,QRSL1,KCTD12,CDC42,BET1,TOMM22,ESR2,PTPMT1,CCDC90B,LIG3,TACO1,CCNF,UBE2H,LSM14B,THTPA,BRCA1,FBXW11,TUFM,ATP5F1A,CUL3,PMPCA,MRM2,ETFBKMT,FMC1,AUH,MYC,MTG2,CSK,IMMP2L,RIGI,FASTKD5,HSPE1,TOLLIP,CHCHD2,H3C1,G3BP1,COX8A,HINT2,HSPD1,EHD4,MAP1B,DHRS3,NDUFS3,PDHA1,AURKAIP1,MAP1LC3B,MRPL11,TOP3B,RAF1,FASLG,RMND1,COX14,EGLN3,FZR1,FAHD1,GATD3,LDLR,COX4I1,PHB1,FBXO32,SSBP1,AIFM1,SDHB,MRPS26,CDKN1B,CHCHD1,RHOG,BABAM1,EMC4,GRSF1,MTRF1 |
| 5.171e-07 | -14.48 | LSM2 (LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 57819 | 170 | 78 | 19454 | 5460 |
LSM8,COIL,FBXW7,RBM22,PPIH,LSM12,PRPF4,SNRPA,HEXIM1,SNRPN,PPP1R8,SF3A1,BCCIP,ESR2,ACTB,SNRNP40,TRIM54,RALA,ZMAT2,SNRPD2,PRMT5,SNRPD1,RSRC1,PSPC1,PNMA1,RIT1,CRMP1,LMNB1,GEMIN8,LSM6,SNRPB,PRPF31,SMN1,SSRP1,SNRPG,MEPCE,HNRNPK,CTNNBL1,CDC40,DHX16,TSSC4,ZBTB16,KRAS,G3BP1,LSM4,ERG28,LSM14A,HNRNPA2B1,PQBP1,NUPR1,SART3,SNRPE,ZRANB2,IK,JUN,SOX2,CD2BP2,WBP11,DHX38,CDC5L,DKC1,RBM42,SNX1,LSM5,TOP1,BUD31,SNRPA1,SNRPD3,FZR1,RAB1B,RBM5,PRCC,USP15,YWHAB,LSM3,SNRNP70,DDX23,EDC3 |
| 5.188e-07 | -14.47 | protein ubiquitination | biological process | GO:0016567 | 620 | 239 | 18204 | 5365 |
RNF126,SYVN1,CAND1,OS9,PRPF19,ANAPC11,E4F1,MED31,TRIM24,UBE2D1,MARCHF4,UBE2N,WDSUB1,DCAF5,TOPORS,SKP1,TRIM63,CBL,PCMTD1,SPSB1,TRIM22,RNF208,TRIM8,TNFAIP3,CTNNB1,RING1,RNF11,FBXO9,NEDD8,WDR77,RLIM,KLHL15,RNF103,PPP1R11,FEM1C,KLHL12,RNF39,UCHL3,DCAF11,UBE2W,ASB3,RNF167,MARCHF9,RNF128,UBA52,RNF8,RPS27A,ISG15,MARCHF3,AKT1,DCAF16,SIAH2,FEM1B,MSL2,KBTBD2,UBE2V1,TRIM37,HERC4,UBE2G2,UBE2V2,MED27,FBXO25,USP5,VPS18,RNF7,CBFB,TNKS,NEURL2,RC3H2,NMI,IFI27,TRIM11,SOCS3,UBE2S,TRIM26,RNF113A,TNKS2,KLHL24,ANAPC2,ZBTB16,WWP1,TRIM54,UBE2B,BRCA1,KLHL3,SMURF1,SOCS5,SPOP,CDC20,FZR1,SOCS2,UBB,FBXO32,KBTBD13,TRAF3IP2,RCHY1,FBXO11,ANAPC4,CDC16,UBE2K,UBE2E2,BRAP,TRIM68,WWP2,RNF14,UBE3A,DCAF4,KLHL7,PELI1,RNF34,UBE2A,TRAF7,KLHL25,WSB1,SOCS4,NEUROD2,RNF181,MED21,SHPRH,MARCHF5,PELI3,HERC3,RNF122,HECTD3,TRIM34,TNFAIP1,RNF141,TRIM23,RNF152,RAG1,FBXW11,ATG3,IRF2BPL,UBE2E3,RNF26,RNF40,FBXO3,RNF133,RNF10,TRAF6,CCNF,MYLIP,NAE1,NDP,KCTD9,RNF144B,ASB1,KBTBD6,ELOC,TRIM62,IRF2BP1,TRIM6,BIRC2,TRAF1,UBE2L3,CDK8,TRIM32,FBXO31,TRAF2,KCTD10,MUL1,NT5C2,APPBP2,TRIM5,MED11,FBXW7,HDAC6,HECW1,RNF5,RNF182,MED10,CISH,KLHL9,MED30,ANAPC13,OTULIN,BFAR,FEM1A,STUB1,KCTD11,RNF115,SPSB3,CCAR1,FBXO22,RBCK1,TRIM15,SIAH1,TRIM44,CUL2,RNF139,DET1,UBE2H,FBXO7,NFE2L2,NBN,ASB8,AREL1,TRIM3,RNF187,ASB7,HECTD1,UBR7,CDCA3,TRIM10,KLHL22,RNF20,NQO1,ZNRF1,TRIM52,COP1,CUL3,UBE2D3,ANAPC16,TRIM45,ZC4H2,VCPIP1,CDC23,RNF121,MED17,FBXL3,CDC26,SPOPL,MDM2,RNF146,DTL,FBXL7,TRIM21,TRIM27,RAB40AL,RNF41,ENC1,CBLL1,ANKIB1,FBXO30,CRBN,HUWE1,ASB11,TRIM35,G2E3 |
| 5.200e-07 | -14.47 | MAP2K5 (mitogen-activated protein kinase kinase 5) | protein interactions | 5607 | 119 | 59 | 19454 | 5460 |
TP53,CDK4,CCT5,RAF1,MAP2K3,GUCD1,TUBB4B,CBX3,LSM14A,SLC25A11,CCT8,CDKN2C,MORC2,BAG2,PIK3CG,THRAP3,DUSP21,RPL28,PFDN5,HMGA1,BECN1,HSPB1,MAP2K6,H2AZ1,CDK6,GRM1,TCP1,FZR1,HSP90AB1,CCT7,ASRGL1,LNX2,MACROH2A2,SLC25A3,MET,PARD6A,STAMBP,SQSTM1,TERT,HSPA8,ELOF1,NF2,SFN,AKT1,MYC,PPP1CC,ATP5F1A,CHTOP,YWHAZ,CCT2,HSP90AA1,EPHA2,STK11,ENO1,TUBA1B,BAD,TRAF7,TUBB,MAP3K3 |
| 5.200e-07 | -14.47 | STBD1 (starch binding domain 1) | protein interactions | 8987 | 119 | 59 | 19454 | 5460 |
AKAP1,RAB5A,RAB9A,DERL1,PXMP2,PYGB,STX7,GABARAP,OTULINL,RND2,SEC62,CDC42,GABARAPL2,ST7,TOMM22,CAV2,SSR1,RMDN3,SEC61B,PPP1R3C,SEC63,PYGM,RAB11A,FIS1,CYP2C9,ZNF787,TMT1A,MEPCE,FKBP8,RIGI,RAB3B,GABARAPL1,DNAJC25,MTCH2,TP53,GBE1,STIM1,RPN1,PTRH2,RAB4A,GJA1,MAP1LC3A,XPO5,HSD17B11,RAC2,PTPN1,RAB35,GYS1,LMAN1,TMPO,DNAJC1,GPRASP2,LAMP3,MOV10,RAB5C,MARCHF5,SLC25A46,RHOG,ESYT1 |
| 5.222e-07 | -14.47 | RAB25 (RAB25, member RAS oncogene family) | protein interactions | 57111 | 263 | 111 | 19454 | 5460 |
EHD1,IL6ST,NOTCH2,MED31,CNDP2,VAPB,AKAP1,CSRP1,STX7,LYPLA2,CAPG,NIBAN2,GPR176,LDHB,RAB11A,SLC38A1,FAM91A1,EFHD2,RAN,ESR2,CLIC4,TAGLN2,SSH3,SOX2,NUDCD3,STBD1,ARFGAP1,STX12,ITGB5,AP2S1,RAB4A,GDI2,SCYL2,FLOT1,SEMA4C,PPFIBP1,TBC1D5,TAF7,NCK1,AGR2,PLEKHO2,STX5,SWAP70,CACYBP,WDR44,RAB11B,HNRNPL,OCRL,SNX1,SNX2,SYNRG,CDK7,PKIG,ARHGAP1,LEMD3,SDCBP,STX17,MTDH,ITGA2,RTN4,ARFIP1,MAVS,MME,YKT6,STK38,EXOC5,GORASP2,C9orf72,PTPN11,EPHA2,ATP1A1,EIF3G,ARFGAP3,SH3BP5L,STX10,VAMP3,OPTN,NECTIN2,CTTN,LDHA,TMOD3,RAB14,YES1,SNX3,MGARP,ARHGAP12,SNAP29,CCDC47,EXOC3,TFRC,ACVR1,NHERF1,SNAP23,RAB1A,EHD4,DLG1,CTNND1,RAB3B,COMMD5,BMPR1B,PGAM1,CNN3,SMAD4,ESYT1,SHC1,RAP1B,PTPN1,ITGA6,EHBP1,STX6,TMPO |
| 5.275e-07 | -14.46 | UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII) | protein interactions | 27089 | 151 | 71 | 19454 | 5460 |
CYC1,SLC25A3,HAUS2,RPA2,COX7B2,HSP90B1,UQCRC1,BORCS6,ATG16L1,TOMM22,FTL,PDHB,NDUFS2,UFL1,PHB2,HADHA,RPA3,PML,NRP1,CDC73,ATP1A1,NLRP3,UBE2H,RIT1,TOMM40,COX6B1,NDUFB7,MGST3,ATP5F1B,LAMTOR3,CPT2,ACAT1,LMBR1L,UQCRC2,VDAC2,OPTN,GPD2,PDHA1,NDUFS3,COX4I2,FAF2,FBP1,ATP5PB,BPIFA2,NDUFA2,MTCH2,RAB1A,SFXN1,NDUFA4,CIART,UQCR11,NDUFB8,ATP1B1,DDRGK1,ATP5MG,STOML2,EGLN3,UQCRH,ATP5PD,CYSTM1,NDUFS8,ILVBL,LMAN1,WIF1,TMEM248,RAB1B,CORO1C,ATP6V1A,SSBP1,PHB1,COX4I1 |
| 5.323e-07 | -14.45 | G6PD (glucose-6-phosphate dehydrogenase) | protein interactions | 2539 | 195 | 87 | 19454 | 5460 |
UBE2V1,RAD23B,NHERF1,ERO1A,PC,RAB1A,SEPHS1,HDAC6,PGAM1,EMC4,DNAJC7,IAH1,CAV1,G6PD,CDC42,CAPN1,SHOC2,RPA2,IDH2,METTL14,RNF113A,ARFIP1,RPA3,BAP1,PPP1R2,MAT2A,CDC73,ATP1A1,UBE2H,CCNF,STUB1,VIRMA,DYRK1A,ZNF622,EIF4H,PRKCE,PPAT,SOX2,TPD52,RANBP1,MTMR2,EZH2,PLS3,AKT2,CA10,SAR1B,UFM1,TNF,KRAS,TRIM37,YWHAH,YWHAG,XPO1,GSTM3,NAB2,UBFD1,HSPB1,YWHAB,AGR2,TRMT61A,EGLN3,OCRL,RPE,CNDP2,PAK2,MAP2K1,ISOC1,HSPA8,HSCB,STAU1,BAG3,MYC,SFN,RAB11A,LDHB,PSMA4,GFUS,RIT1,ARMT1,CKB,MYO6,YWHAZ,AP2M1,RAN,MAT2B,ESR2,FBXO22 |
| 5.344e-07 | -14.44 | U4/U6 x U5 tri-snRNP complex | cellular component | GO:0046540 | 40 | 27 | 19108 | 5553 |
LSM5,SNRPA,SNRPD1,LSM3,SNRPB,SNRPD3,DDX23,SNRNP40,SART3,ZMAT2,SNRPN,RBM42,TXNL4A,LSM8,PRPF18,SNRPD2,LSM6,LSM2,PPIH,CD2BP2,LSM4,SNRNP27,PRPF4,USP39,SNRPE,SNRPG,PRPF31 |
| 5.344e-07 | -14.44 | spliceosomal tri-snRNP complex | cellular component | GO:0097526 | 40 | 27 | 19108 | 5553 |
ZMAT2,SNRPN,SART3,PRPF18,LSM8,RBM42,TXNL4A,DDX23,SNRNP40,SNRPB,SNRPD3,SNRPD1,LSM3,LSM5,SNRPA,SNRPE,SNRPG,USP39,PRPF31,LSM4,SNRNP27,PRPF4,LSM2,CD2BP2,PPIH,LSM6,SNRPD2 |
| 5.439e-07 | -14.42 | IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2) | protein interactions | 10644 | 342 | 138 | 19454 | 5460 |
MRPS18B,MIR9-3,DHX9,MIR200A,MEPCE,MIRLET7C,MIR16-2,DUSP1,MIR15A,MIR200C,APOBEC3D,YTHDF2,MIR17,PRR3,MIR25,MIR106B,MRPS9,SYNCRIP,MIR429,CDK9,MRPS23,CAND1,FZR1,MIRLET7G,HDAC6,MOV10,GRSF1,MIR34A,TDRD7,SNRNP70,LSM12,MIRLET7I,MIR34C,SMG5,RPA3,MIR10B,BAP1,SIRT7,MIR205,AATF,MIR29A,MIR107,MIR7-3,FBXW7,AGO1,MIR1-2,RBMS2,CFTR,MIR34B,HEXIM1,MIR21,MIR7-1,HECTD1,KLF4,RPA2,MRPS34,RPS20,MIR16-1,EIF2AK2,VIRMA,NDN,CIAO1,IGF2BP1,ELAVL2,UBE2H,MRPS16,RC3H2,MIR145,MIR206,ZC3H7A,COX8A,LSM14A,RBM3,PABPC1,HNRNPA2B1,MIR9-2,G3BP1,NUP42,MIR155,MIR222,SOX2,TOP3B,RAF1,GTPBP1,GLE1,MIR141,MIR214,MIR7-2,PHB1,FUBP3,PAIP1,HNRNPL,MIR9-1,CPEB1,MIR29C,HNRNPA1,DDRGK1,IFI16,SAV1,WWP2,MRPS35,MIR143,DDX1,HNRNPD,MIR221,MRPS26,MIR1-1,MIR140,MIR31,HSPA8,RAB5A,AKAP1,MCRIP2,MIR106A,G3BP2,MRPS7,UFL1,STAU1,YTHDF1,PABPC5,DUSP14,LARP4B,CDC7,MIRLET7B,KTI12,CMTR1,MIRLET7D,PRRC2A,MIR98,BTF3,MYC,CUL3,HNRNPAB,HNRNPC,GRB10,MIR363,LSM14B,DCAF4 |
| 5.493e-07 | -14.41 | oxidoreductase activity | molecular function | GO:0016491 | 709 | 272 | 18094 | 5411 |
GSTM2,DIO1,NDUFS3,TXN,CYGB,RSBN1L,ETFA,KCNAB1,CYP1B1,CYP2C9,CYB561,GSTO1,SELENOF,CYP4F12,CYP39A1,PRDX4,GPD2,GSTP1,GPX7,TYW5,NDUFC2,GFOD2,ALOX5AP,CLIC2,CYP2D6,PDIA2,PDHA1,DHRS13,NDUFB7,SOD2,SDHC,SELENON,HBB,PIR,AKR1B1,OGDHL,KDM4B,NDUFA12,PCYOX1L,FA2H,SDR42E1,PGK1,GPX3,TXNRD1,SORD,DBH,COX8A,P4HA2,CYP4F8,FADS2,NQO1,PYROXD2,CRYM,NDUFA5,DEGS1,HMOX2,TMX4,FMO1,HSD17B1,TXNDC17,ACADS,CYC1,CYBRD1,GFOD1,GSTK1,GPX6,NDUFB5,TMX3,P3H1,HSDL1,ADH1A,GPX5,HBA1,LBR,GSTT1,TXNL1,UQCRC1,FAXDC2,TP53I3,AIFM1,PDHB,SRD5A3,FRRS1,PNPO,FMO3,OGFOD3,TXNDC12,HSDL2,DNAJC10,IDH1,TXNRD2,PTGES,NDUFS2,HSD17B8,COX7B,DIO3,CYB5R1,SRXN1,PRDX6,MSRB3,HSD17B6,DECR2,ALDH1A3,MTHFD2L,CYB561D2,GPX1,CYP1A1,CYP27A1,NDUFV2,PYCR1,PCBD1,KDM1A,HSD11B1,DHRS4L1,MDH1,DHRS7,TXNRD3,COX6B1,AKR7A2,DOHH,IDH3A,G6PD,NDUFA2,HBE1,NDUFB10,CYB5R4,NGB,HADHA,MGST3,RDH11,RDH10,NSDHL,LACC1,LDHA,ALKBH4,CYP21A2,CH25H,CYP11B1,LDHB,PYCR2,PEDS1,ALKBH2,CYB5R3,ACADSB,IPCEF1,CYP3A5,SOD3,SELENOT,AOX1,CYP3A43,COX4I1,AKR1E2,GPX2,NDUFB8,BLVRA,ADH1B,KGD4,GPHN,NDUFS6,PDIA3,COX6A2,DHRS1,TPH2,MOXD1,DIO2,AKR1C2,SDHB,CYB5B,TECR,EGLN3,GAPDH,FAR2,DHRS11,IDO1,DBT,LDHAL6B,CDO1,CYP2C8,CYP17A1,NDUFA4,UGDH,TMX2,DLAT,RRM1,CRYL1,EGLN2,DHRS4,COX5A,CYP26A1,KIAA1191,CBR3,CBR4,AKR1A1,MSRB1,ALKBH5,NDUFA1,RIOX2,PRDX1,GPX4,AKR1C1,SPR,SOD1,RETSAT,NDUFB4,CYB5A,CYP2C18,COX7A1,CRYZ,IDH3B,CYP11B2,GSTA1,CHDH,SESN3,MTARC2,OXNAD1,SESN2,APEX1,VKORC1L1,ADO,CHCHD4,SELENOM,PHYH,CYP27B1,RDH12,HSD17B3,KDM2A,CYP7A1,MECR,GFUS,POR,PRDX2,CYP2F1,CTBP1,SDR16C5,CYP4V2,DUS4L,CYP2R1,KDSR,CCS,SC5D,PDIA6,UQCRH,DHRS3,HADH,ALKBH3,HR,NDUFB6,FMO2,ERO1A,MGST2,HBM,COX4I2,PAOX,DHRS7B,CRAT,GLRX2,MSMO1,SCD5,MMACHC,GSTO2,FXN,EHHADH,NDUFS8,ACOX1,CYP4F22,HSD17B10,HSD17B11,PRDX3,FTH1,GLRX,ALDH1L1,IDH2 |
| 5.499e-07 | -14.41 | VTI1B (vesicle transport through interaction with t-SNAREs 1B) | protein interactions | 10490 | 184 | 83 | 19454 | 5460 |
TMEM74,SYT2,STX10,PPP2R5E,SESTD1,VAMP3,LMBR1L,EIF4A3,MAD2L2,ESR2,RNASEK,ACP2,SYNE4,REEP4,RHOJ,MANSC1,CREB3,KDSR,CSK,VAMP5,SCN3B,SCFD1,NAPA,CASC3,STXBP6,LAMTOR1,RHOB,RAB5A,RAB9A,JAGN1,STX7,TNFSF12,NAPG,OTULINL,CDC42,CFTR,DUSP22,CDK7,NUP62,ATG16L1,BET1,SEC22B,STAMBP,LMNA,PTP4A2,CD46,USE1,MANBAL,GPR35,EIF2B3,STX5,RAC2,ARL10,VAMP7,STX6,CRB3,CAV1,EIF2B5,EIF2B2,LAMP3,EXOC1,MDFI,ATG9A,LAMP2,PTPN5,RAB5C,STX1A,STAMBPL1,FCGR1A,RHOG,MED21,ECD,STX18,STX8,STX11,KRAS,MAP1LC3B,SNAP29,STX12,AP1S2,TMEM14B,AQP3,RAB4A |
| 5.516e-07 | -14.41 | RAB11A (RAB11A, member RAS oncogene family) | protein interactions | 8766 | 822 | 294 | 19454 | 5460 |
PSEN1,ARF4,CTNND1,IGF1R,HSD17B10,SNAP23,GNG5,DLG1,NKRF,EHD4,NSDHL,RAB1A,KRIT1,SLC29A1,MAP1LC3B,CCDC47,CAV1,G6PD,NCBP2,ARF6,PPP1R18,CDCA3,HSD17B11,KRR1,EHBP1,RCHY1,SRPRA,PTPN1,OSBPL8,CNN3,EXOC2,ESYT1,SLC2A1,RAB23,LAMP3,ATP5MG,TMEM199,AATF,YKT6,ITGA2,MAVS,RTN4,MTDH,GRIA2,DCTN6,MME,PDCL,NOL7,SLC12A2,GOLGA5,PICALM,DCTN4,JUP,CNP,SYNRG,ARHGAP1,SEC22B,ATG16L1,RABL3,TPRA1,VIRMA,FERMT2,TECR,SLC25A4,YES1,SNX3,TMOD3,CTTN,SMAP2,SCAMP2,GAB1,OPTN,VAMP3,NAPA,NRP1,EPHA2,STK24,SH3BP5L,ARFGAP3,HMOX2,DEPDC1B,ATP5F1A,SEC13,RETREG1,FLOT1,SEMA4C,TMT1A,SCYL2,RPS11,ITGB5,STX12,GDI2,EZH2,VAMP2,SCHIP1,STIM1,IFNGR1,PPP2R1A,FAF2,MACO1,TPD52,ARFGAP1,RAF1,WDR44,RAB11B,SNX2,SNX1,SPTAN1,OCRL,XPO5,PLEKHO2,OCIAD2,PHB1,PSMB4,MRTO4,WDR6,CDK5RAP3,WDR11,MARCHF5,UBXN6,PRDX1,ATP6V1G1,STX7,PXMP2,CSRP1,NOP53,SLC35F2,HADHA,PMAIP1,EXD2,VPS18,ABCB1,VAPB,RAB6A,EHD1,NOTCH2,CLIC4,ACTB,RANBP6,SEC61B,CYB5R3,GRIA1,ARF1,FAM91A1,SCFD1,LMNB1,RHOB,CAPG,MAP3K21,RAB11A,NOP16,PKP4,VEZT,NIBAN2,SLC6A8,SRPRB,RAB3B,AKAP12,H3C1,CHMP1B,RAB13,SLC16A1,PALM2AKAP2,RBM34,NHERF1,TFRC,EXOC3,UBIAD1,UBL4A,SNAP29,SURF6,STX6,TMPO,SLC38A2,LMAN1,CYSTM1,SPPL3,RAC2,TRAPPC3,RAP1B,SLC39A10,CAMLG,ITGA6,CD274,STT3A,COQ8A,COPS5,PGAM1,KARS1,HSPA5,GRPEL1,STK38,RAB9A,ARFIP1,PSEN2,TEX264,CSNK1G3,LEMD3,HEXIM1,VIPAS39,IDH2,RPA2,SDCBP,CFTR,CDC42,SPTBN1,SRC,DAPK1,STX10,SLC1A1,EIF2S2,GNAO1,NECTIN2,CALU,UBE2H,SNX5,ATP1A1,BICD2,ATP1B3,EIF3G,CISD1,GORASP2,DNAJC5,EXOC5,PTPN11,SPRED1,SLC25A1,RAB2A,POLDIP3,VAMP8,ROCK2,VDAC1,SLC20A2,KRAS,ACTR1B,EFNB1,RABGGTB,TMEM87A,GNA11,CRKL,PDHA1,RAB4A,PLS3,ISG15,SERPINA3,SOX2,ARFGEF1,STBD1,LANCL1,VAMP7,LYAR,ASIC1,RAB1B,AFTPH,EIF2S1,STX5,TRAPPC10,SWAP70,AGR2,NCK1,TBC1D5,EXOC1,CTNNB1,YWHAG,PPFIBP1,RAB5C,LAMP2,LYPLA2,PHB2,STAU1,RAB5A,AKAP1,ADSS2,TMEM115,SEC62,IL6ST,MTMR6,ATP6AP2,TRIM29,TAGLN2,FAM83B,EFHD2,SERPINH1,GTPBP2,ICAM1,SLC38A1,ATG3,FTSJ3,LAMTOR1,SLC1A3,TBC1D1,RALGAPA2,GPR176,OST4 |
| 5.620e-07 | -14.39 | C9orf72 (C9orf72-SMCR8 complex subunit) | protein interactions | 203228 | 76 | 42 | 19454 | 5460 |
SYN3,COIL,TOMM20,SMN1,FKBP8,RAB8B,EXD2,RAB9A,MAVS,PTRH2,FURIN,ATG16L1,TOMM22,MTCH2,TANK,AZI2,DNAJC25,OTULINL,ST7,RAB6A,DNAJC1,EIF2B2,RAB33A,RAB39B,SEC63,COX14,HMG20A,NMI,RAB35,PTPN1,POP7,RMDN3,VRTN,LAMTOR1,RHOG,FIS1,RB1CC1,C9orf72,LAMP2,SLC25A46,MARCHF5,ATG101 |
| 5.691e-07 | -14.38 | VAMP8 (vesicle associated membrane protein 8) | protein interactions | 8673 | 96 | 50 | 19454 | 5460 |
STX18,SNAP23,STX8,SYPL1,STX11,KRAS,RAB3B,MAP1LC3B,SNAP29,TOP3B,TRIM6,STX12,VAMP2,RAB4A,HRAS,UBE2G2,STX6,CAV1,RAB11B,ARF6,SNAP25,LAMP3,LAMP2,MDFI,RAB5C,STX1A,RHOG,MED21,RAB9A,RAB5A,RHOU,RPA3,STX7,NAPG,USP8,CDC42,BET1,STAMBP,PTP4A2,RPA2,STX17,GNPDA1,VAMP3,RHOJ,DNAJC5,RAB11A,VAMP5,NAPA,LAMTOR1,RHOB |
| 5.704e-07 | -14.38 | response to lipopolysaccharide | biological process | GO:0032496 | 333 | 140 | 18204 | 5365 |
TLR2,CD14,NLRP3,CCR5,TRAF6,TICAM2,RPL13A,XBP1,THBD,MIR20A,MIR17,HNRNPA0,TRIB1,PDCD1LG2,CYP1A1,LITAF,MAPKAPK3,CDK4,CNR1,FBXO3,PLAA,ACP5,MIR187,TIRAP,CXCL10,JAK2,FOS,CCL2,CITED1,DIO2,FOSL2,LTA,PTGER1,MRC1,NFKB1,PRKCE,HDAC5,IRF8,KCNJ8,AKT1,FMO1,WDR83,IL1B,CD40,CEBPE,HMGB1,PTPN22,NFKBIB,MTDH,CXCL1,PYCARD,STAP1,DUSP10,SELENOS,NFKBIL1,S100A8,CCR7,MAP2K3,IL1A,IL10,PTGFR,NFKBIA,PLSCR3,TNF,CXCL11,LIAS,IL18BP,TRIM6,LY96,TNFAIP3,FGF10,GJB2,GSTP1,CX3CR1,PLSCR4,MGST2,MIR342,MYD88,IRAK4,CHMP5,PCK2,NQO1,TLR9,TNFRSF1B,TSPO,SLPI,GFI1,MIR21,PTGER4,CDC73,CXCL3,MIR146A,CXCL13,OPRK1,CLDN1,CAPN2,CYP27B1,ALPL,TICAM1,EPO,MEF2C,LDOC1,CD80,CD36,BCL10,REN,FOXP3,SRC,IL12A,CD274,LILRB1,UGT1A1,PRDX2,MIR140,PELI1,PDE4B,TLR4,FASLG,CSF2,IRF3,IDO1,AKAP12,TAB2,IL12B,CXCL9,FOXP1,CXCL8,MIR223,MMP9,SOD2,CD86,CAMP,IFNAR1,PRDX3,IL13,MIR142,CNP,PTGER2,PDCD4,IL6 |
| 5.749e-07 | -14.37 | ANXA2 (annexin A2) | protein interactions | 302 | 366 | 146 | 19454 | 5460 |
RAB1A,HSD17B10,RPS13,RIGI,SMN1,TP53,INSIG2,H2AX,MAP1LC3B,EEF1A1,GGCT,TNFAIP8L1,DISC1,RNF8,SYNCRIP,EFNA3,AIFM1,CD274,TCEAL8,CD4,FZR1,PLG,CDK9,TMPO,NFKB1,ADIPOR2,USP2,HDAC6,SHC1,DNAJC7,RPS2,DVL2,BAP1,RPA3,PML,PRKCB,RNF113A,MTDH,FBXW7,HMGB1,PIAS1,HSPA5,BCL6,UBA52,NEK2,CDC42,CDK7,CFTR,JUP,RPA2,METTL14,PRKCA,HEXIM1,WTAP,STAT6,CCNF,TRIM27,CALML5,MACROH2A1,PTEN,RAB14,CTSB,TENT2,TFEB,SRC,VIRMA,AKT1,CTSD,PTPN11,ARHGAP21,DNAJC8,SPOP,BICD2,LGALS8,CDC73,UBE2H,HNRNPA2B1,TRIM21,EWSR1,PCNA,CCDC32,UBE3A,TRIM26,TRIM37,S100A10,UBE2A,CBLL1,B3GNT2,LYPLA1,ERRFI1,RAF1,ANP32A,TXNRD1,PPP2R1A,ISG15,SOX2,MSX2,EZH2,PDHA1,CHMP4C,FABP5,FOLR1,PHB1,S100A8,KRT8,SNX17,HNRNPL,CACYBP,PDIA3,DCAF4L2,HMGA1,WWP2,MAP1S,HNRNPA1,CSTA,AGR2,PPM1B,MGMT,PEBP1,DDX39B,NMRAL1,HSPA8,TERT,PMAIP1,EP300,EMC1,CDSN,AZGP1,PPP1CB,PPT1,PIH1D1,S100A6,DLST,RNF208,CAVIN2,PRDX2,MYC,CUL2,RAB11A,BTF3,BAG3,GALE,YWHAZ,RHOB,SP1,SETD7 |
| 5.752e-07 | -14.37 | TNFR2 non-canonical NF-kB pathway | REACTOME pathways | R-HSA-5668541 | 104 | 57 | 10285 | 3229 |
UBE2M,PSMD4,RPS27A,PSMA1,TNFSF13,TRAF2,PSMC3,SEM1,PSMB9,PSMB4,PSMD6,PSME2,BIRC2,PSMA6,TNFRSF9,TNFSF18,PSMB2,PSMD1,PSMC1,PSMD12,LTB,TNFSF8,MAP3K14,TNF,UBB,UBA52,TNFRSF14,CD40,PSMD14,PSMD7,TNFSF15,PSME1,CD40LG,SKP1,UBA3,PSMD10,LTA,PSMB3,PSMB6,FBXW11,PSMA2,PSMB10,PSMA5,PSMC5,PSMB11,LTBR,PSMA4,FASLG,EDA2R,PSMC4,TNFSF12,PSMB5,PSMA3,PSMB1,TNFRSF1B,PSMB7,PSMD3 |
| 5.766e-07 | -14.37 | protein localization to mitochondrion | biological process | GO:0070585 | 85 | 47 | 18204 | 5365 |
CHCHD4,MAVS,TIMM29,MAIP1,TIMM23,TOMM20,SAMM50,FBXO7,TIMM8B,TOMM40L,TOMM6,DNLZ,TIMM8A,AIP,MTX2,TSPO,AGK,TIMM17A,TIMM21,FIS1,TOMM7,TRMT10B,BCS1L,PMPCA,FKBP8,DNAJC19,ROMO1,IMMP2L,GRPEL2,SARM1,RALA,TIMM13,TOMM40,BAX,AKT1,AIFM1,HSPD1,MARCHF5,MGARP,TOMM22,GRPEL1,MTCH2,DDIT3,TOMM70,ISG15,HSP90AA1,TIMM10 |
| 5.778e-07 | -14.36 | SGTA (small glutamine rich tetratricopeptide repeat co-chaperone alpha) | protein interactions | 6449 | 275 | 115 | 19454 | 5460 |
GPX7,TMEM31,TFRC,HSPA13,ARPC3,CAPZA2,NPVF,UBL4A,CD2BP2,LSM4,ADIPOQ,CAPZA1,SOD3,EDA2R,PPIC,SPP1,TIAM1,SMCHD1,MSMB,EDEM1,MSTN,FZR1,TWSG1,PRNP,TMPO,CD99L2,CD274,IER3,ADAM21,DSTN,SEC23A,CXCL8,GABARAPL2,WFDC5,PIAS1,TUSC2,BAP1,IRF3,VIP,MAVS,SDF2L1,FERD3L,NRP1,COL1A2,PSMB2,ST13,DNAJC5,PHKA1,USP14,NRSN2,F11R,ADRM1,TXNDC12,OPTN,SGTA,RPN1,GDI2,CTSA,PSORS1C2,GHR,WBP1L,ACTN4,CYB5R1,RPL29,SPINK9,PSMD12,AHCYL1,CPLX1,FSTL1,PABPC1,PCNA,LDLRAD4,BAG2,ERP29,SYT4,AGR2,PDCD10,YWHAB,PPIB,HNRNPL,C1QTNF1,PGR,RNF144B,AASDHPPT,WFDC13,HSP90AB1,SDC4,STX5,ADSS2,ACAA2,TMEM174,TMUB2,IL6ST,PTN,CDSN,TNFSF12,NMRAL1,HSPA8,TRIM5,NUP50,SLPI,PSMD14,RBM27,SCFD1,HSP90AA1,BTF3,GGH,SRGN,ACTB,PPP1R3C,USP5,LMBR1L,CD79B,DKK3,SEC61B |
| 5.806e-07 | -14.36 | cellular detoxification | biological process | GO:1990748 | 117 | 60 | 18204 | 5365 |
SESN2,IPCEF1,GSTA1,MGST2,SELENOW,GSTO1,MTARC2,GPX4,NQO1,GSTO2,HBE1,SOD1,TXNRD2,TXNRD3,GSTK1,GPX5,HBB,GSTT1,PRDX4,CLIC2,MGST3,ALOX5AP,HBM,SRXN1,AKR1A1,GPX3,HP,CCS,GSTM2,RDH11,ESD,SOD3,PRDX1,GPX7,PRDX2,GPX6,SELENOT,SELENOS,ABCG2,LANCL1,PRDX6,GPX2,ALB,GSTM3,UBIAD1,MT3,SOD2,GPX1,PTGES,PRDX3,HBA1,TP53INP1,CYGB,SELENOF,TXNRD1,GSTP1,RAB29,TXN,RDH12,TXNDC17 |
| 5.855e-07 | -14.35 | EIF3D (eukaryotic translation initiation factor 3 subunit D) | protein interactions | 8664 | 232 | 100 | 19454 | 5460 |
RPA2,HEXIM1,UBE2M,TFIP11,ATG16L1,EIF3J,CDC42,FBXW7,HSPA5,EIF4E,MBD3,SIRT7,RPA3,SOD1,BAP1,TRIM23,EIF3G,UBE2H,CIAO1,RSPH1,CEP70,TUSC1,CFL1,NDN,VIRMA,METAP2,PSPC1,RPS20,RPS12,CSNK2B,TRIM27,NUPR1,SRP72,POLR2G,MTA3,EIF4EBP2,EIF3E,MEPCE,HSD17B10,RPL23A,ABCE1,USP3,ENY2,CSNK2A1,EIF2B5,CAND1,RPS16,FZR1,CD274,CD4,ADNP,EIF4B,BEND5,SUPT4H1,STAU1,UFL1,EIF1B,RPS28,EP300,HSPA8,SAT1,DCAF4,FBXW11,CUL3,CREBBP,MYC,BTF3,RPL35,TENT5C,MATR3,PSMD4,EIF4A2,ESR2,EIF3K,RPS9,EZH2,SART3,POLR2C,RPS11,RAF1,KRAS,G3BP1,CBLL1,RAD21,UBE2A,RPS4X,PSMD12,SRSF7,PICK1,RPL23,POU5F1,HAX1,RB1CC1,WWP2,DDRGK1,EIF3D,XPO1,KCTD10,CHMP2A,HOMER3 |
| 5.886e-07 | -14.35 | presynapse | cellular component | GO:0098793 | 569 | 219 | 19108 | 5553 |
DRD1,ELK1,CNR1,YWHAH,KCNH1,DNM2,FLOT1,PHB2,ARL6IP5,ACTB,NTF4,CACNB2,CTNND1,ARF6,RPL22,VPS18,PRRT1,SYNPR,CDK5,SYNGR1,ATP6V1G1,SLC35F1,SLC1A1,GAD2,LGI3,BACE1,SLC6A3,SCAMP5,STXBP1,CHRM1,ADORA3,RAB3A,APH1A,ATP8A1,PPFIA2,KCNJ11,SLC6A2,STX12,HSPA8,SYNGR4,FLRT3,PSEN2,AP2M1,PRKCB,STX1A,ASIC1,SEPTIN6,SNAP91,ATP2B4,GRIK1,RAB13,IQSEC1,PPFIBP1,YWHAG,NTRK2,COPS5,SNAPIN,ATP6AP2,CTNNB1,FZD3,RIMS4,SYN3,KCNJ10,SNAP23,RAB5C,RABAC1,VAMP1,WNT7A,CTBP1,OPRK1,PRNP,SLC29A1,KCNC1,CDK5R1,SYNDIG1,SYNGR3,SYT4,RAB6B,KCNA3,NEFL,CASK,SYP,SLC32A1,AP2S1,SLC4A8,SLC6A4,NLGN1,RAB11B,STX10,SLC8A1,NLGN2,SLC6A11,HRH3,DNAJC5,SLC4A10,SDCBP,SRSF10,ATP6V1G2,MME,KCNJ8,C9orf72,GRM2,ATP6V1D,RAB3D,PDE4B,CPLX1,NPY5R,STX11,P2RY1,GABBR1,C1QL1,RAB40AL,HCRT,SLC2A1,LRFN3,NPTN,SVOP,LRRC4B,STX16,PCDH17,CPLX2,RIMS3,ATP6V1A,PPFIA3,PPT1,LPAR2,PICK1,CRHBP,SLC17A5,KCTD16,RAB3B,TNIK,DISC1,HTR2A,SV2B,SNAP25,ICA1,TRAPPC4,DLG4,VAC14,SYNGR2,AP3S2,CTTNBP2,CLN8,COPS4,ITGA2,RAP1A,PSENEN,ADORA1,SYPL1,ROGDI,VAMP2,GPM6A,EPHA4,RAB3C,GABRA2,GIT2,SYT2,LIN7B,FCHO2,PRSS12,ZDHHC17,VTI1B,TPBG,PNOC,SNCB,RAB8B,SEMA4C,NTNG2,KCTD12,SNCG,KCNA2,SNAP29,GUCY1B1,ZNRF1,ATP6V1C1,P2RY4,TBC1D24,RGS7BP,CDH8,PICALM,STX7,LAMP5,IGSF21,TMED9,BCL2L1,PPP1CC,PSEN1,CACNB4,CNTN1,LIN7C,CNTNAP1,FXYD6,CHRNB2,UCN,NOG,GRIA1,SLC18B1,STX6,EFNB1,MT3,RAB33B,MTMR2,GRAP,CPLX3,NCSTN,SLC1A2,RAB5A,PDE2A,OPHN1,UBE2L3,PDYN,EXOC3,SLC6A12,SLC35G2,KCNJ3,BORCS5,LPAR1,SLC6A1 |
| 5.910e-07 | -14.34 | POLR2E (RNA polymerase II, I and III subunit E) | protein interactions | 5434 | 278 | 116 | 19454 | 5460 |
TRMT1L,MED9,SUPT5H,PPP2R1A,GTF2E2,POLR2C,POLR2D,TAF10,RUVBL2,RPAP3,KRAS,RUVBL1,SSRP1,WWP2,XPO1,UBE2D1,MED4,RPRD1A,PHB1,POLR2L,POLR3F,EGLN3,PPP1CB,FKBP14,MED31,PIH1D1,SNRPA,FOS,XRCC5,HSPA8,MED13L,HSCB,MED11,SKP1,LMO2,MYC,CUL3,BRMS1,SNRPB,MED10,FAS,BRCA1,HSP90AA1,PFDN2,RPS5,RIT1,POLR1B,PFDN6,MAF1,LMBR1L,INTS10,POLR3B,GTF2F1,POLR2F,GTF2F2,MED17,SPINDOC,TRIM29,POLR2B,MAD2L2,ESR2,RPAP2,EEF1A1,PSMB9,CDK8,POLR2G,NUPR1,HSD17B10,KPNA2,DNAAF10,TRIM63,PDRG1,MDC1,PTGES3,GTF2E1,COPS5,CSNK2A1,POLR3GL,MED27,MED21,MED29,COQ8A,GTF2B,POLR2I,TOP1,ASNSD1,INTS6L,ATG16L1,MED30,POLR1D,CFTR,PAAF1,ZSCAN1,ST7,RPA2,RPRD1B,HSP90B1,UBE2M,RPA3,SOD1,BAP1,PML,ELOF1,FBXW7,STK38,POLR1H,SMARCA5,SEC13,MED22,PPP1CC,UBE2H,CCNF,CSNK2B,INTS12,POLR3H,SRC |
| 6.080e-07 | -14.31 | THOC7 (THO complex subunit 7) | protein interactions | 80145 | 109 | 55 | 19454 | 5460 |
FYTTD1,NIF3L1,CHTOP,ZCRB1,LMNB1,RBM27,ALKBH5,UBE2H,THOC6,USP13,MYC,MED22,RNF40,BTF3,SNRPB,PSPC1,EIF4A3,ENO1,ANAPC2,RPA2,TRMT112,ATG16L1,SF3A1,ZC3H14,BORCS6,MRPL12,PPP1R2,ZC3H15,AATF,SNRPA,CCDC9B,THOC3,RPA3,DDX39B,MNS1,SF3B1,SNRNP70,TNFAIP6,MOV10,NDC80,THOC1,TOP1,RBM42,AKAP17A,THOC2,ALYREF,GNAZ,RAF1,E2F4,DDX39A,SSRP1,POLDIP3,ZC3H11A,RTCB,DHX9 |
| 6.093e-07 | -14.31 | NDUFB10 (NADH:ubiquinone oxidoreductase subunit B10) | protein interactions | 4716 | 130 | 63 | 19454 | 5460 |
MRPS7,UQCC3,PHB2,PIK3R2,SLC25A51,PDHB,HSCB,NDUFC2,CYC1,NDUFA5,SLC25A3,PTPN22,ATP5PO,COX6C,NDUFAF3,TIMMDC1,NDUFAF4,PARL,VIRMA,ACTB,ATP5F1B,MRPL13,CCDC90B,LMBR1L,UQCRC2,OPTN,CCNF,FAS,TUFM,ATP5F1A,NDUFB7,MYC,RIGI,FKBP8,DNAJC30,VDAC1,SFXN1,NDUFA4,NDUFB5,HGS,SLC25A24,RNF181,NDUFA12,NDUFS6,NDUFS3,APOO,MTCH2,NDUFA2,HTR2A,RMND1,SLC25A12,EGLN3,ATP5PD,NDUFS8,GATD3,NDUFA1,COX4I1,PHB1,AIFM1,TMEM70,TPM3,NDUFV2,COX5A |
| 6.098e-07 | -14.31 | IL7R (interleukin 7 receptor) | protein interactions | 3575 | 138 | 66 | 19454 | 5460 |
SNRPA,DDX39B,DDX5,EMG1,SQSTM1,HADHA,SF3B1,HNRNPA0,AGTRAP,RRAGA,IL2RG,SF3A1,HNRNPH3,EIF2AK2,RPS3,FAU,CPSF1,RPS20,SNRPD1,SNRPD2,STAT5A,RPL22,HNRNPC,HNRNPAB,SNRPB,NONO,H1-10,CIRBP,ZNF787,RBM3,PABPC1,RPL31,DHX9,JAK1,G3BP1,KIT,RAD21,SNRPG,HNRNPDL,GTF3C3,SOCS2,RPSA,RPL15,RPL29,IL7,EXOC3,RPL18,SNRPE,ILF2,ALYREF,SDC4,SRP14,SYNCRIP,RPL8,SNRPD3,TOP1,RPL7,HNRNPL,RPL6,PIK3R1,CISH,YWHAG,SNRNP70,MAP4,CBL,HNRNPD |
| 6.135e-07 | -14.30 | SNARE interactions in vesicular transport | KEGG pathways | ko04130 | 34 | 26 | 7161 | 2463 |
VAMP5,USE1,STX18,STX7,SNAP23,VAMP2,STX17,SNAP29,YKT6,SEC22B,STX6,STX1A,BET1,STX10,GOSR1,VAMP3,BET1L,STX5,STX8,VAMP1,STX11,VAMP7,STX16,VTI1B,VAMP8,GOSR2 |
| 6.135e-07 | -14.30 | SNARE interactions in vesicular transport | KEGG pathways | hsa04130 | 34 | 26 | 7161 | 2463 |
STX6,BET1,STX1A,YKT6,SEC22B,STX17,SNAP29,VAMP2,STX7,SNAP23,VAMP5,USE1,STX18,GOSR2,VAMP8,STX16,VTI1B,VAMP7,VAMP1,STX11,STX8,STX5,VAMP3,BET1L,GOSR1,STX10 |
| 6.165e-07 | -14.30 | Degradation of GLI2 by the proteasome | REACTOME pathways | R-HSA-5610783 | 61 | 38 | 10285 | 3229 |
SEM1,PSMB9,PSMD7,PSMD10,PSME2,PSME1,PSMB4,SKP1,PSMD6,RPS27A,PRKACB,UBA52,PSMD4,UBB,PSMD14,PSMC3,PSMA1,PSMB5,PSMA3,PSMC4,PSMC1,PSMD12,PSMB7,PSMD3,PSMB1,PSMB2,PSMD1,PSMA2,PSMB6,CSNK1A1,PSMA6,PSMB3,PSMA4,SUFU,PSMB10,PSMA5,PSMB11,PSMC5 |
| 6.165e-07 | -14.30 | GLI3 is processed to GLI3R by the proteasome | REACTOME pathways | R-HSA-5610785 | 61 | 38 | 10285 | 3229 |
PSMB9,SEM1,PSMD7,PSME2,PSMD10,SKP1,PSMD6,PSMB4,PSME1,UBA52,RPS27A,PRKACB,UBB,PSMD4,PSMD14,PSMC3,PSMA1,PSMA3,PSMB5,PSMD12,PSMC1,PSMC4,PSMD3,PSMB7,PSMB1,PSMA2,PSMB6,PSMD1,PSMB2,PSMB3,PSMA6,CSNK1A1,SUFU,PSMA4,PSMC5,PSMB11,PSMB10,PSMA5 |
| 6.168e-07 | -14.30 | NEDD4L (NEDD4 like E3 ubiquitin protein ligase) | protein interactions | 23327 | 284 | 118 | 19454 | 5460 |
DLG3,RAF1,HGS,LDLRAD4,CDK5,TRIM37,ACVR1B,KRAS,UBE2E2,STOML2,PRKX,SIVA1,CTNNB1,YWHAH,XPO1,YWHAG,UBE2D1,IKBKB,YWHAB,HAX1,SPHK2,MAP1LC3A,HNRNPL,KIF3B,NPC2,SYK,IL2RG,EDEM3,OTULINL,IL6ST,H2AC1,RNF7,CRYAB,PIP4P2,TMEM174,WBP2,PYM1,BMPR1A,ARRDC3,SLC31A1,UBE2D3,RANBP10,MT2A,TGFB1I1,RNF11,SFN,GRB10,CAV3,RHOB,YWHAZ,KCNA3,SP1,APEX2,VDAC2,GRIA1,NDFIP1,PSMD4,SUSD6,TMEM101,TMEM252,H2AX,TFRC,PIK3CA,ILDR1,CYBRD1,TOLLIP,FGF12,RASL10B,LRP3,MOV10,ATP1B1,TMA16,CLIC2,MAGEB1,UBE2N,CD274,SMAD3,RNF128,DECR2,TSC22D3,IFRD2,CPNE1,SURF6,SLC22A8,KCNAB1,MAPKAPK3,RPA3,RHOU,DVL2,GPX4,SLC22A6,LPAR1,CERS2,NF2,UBE2K,LITAF,PRRG1,AATF,HSPA5,NHP2,AKT3,AKT1,TNFAIP3,OGG1,UBE2E3,CCDC22,KCNB1,TMEM255A,SMAD2,MARCHF3,LURAP1,CCNF,ADRM1,RHOJ,DAPK3,MAP3K3,VIRMA,UBE2L3 |
| 6.168e-07 | -14.30 | ASXL1 (ASXL transcriptional regulator 1) | protein interactions | 171023 | 284 | 118 | 19454 | 5460 |
NUP62,SLC25A3,NDUFA5,TRMT112,ISOC1,HADHA,RLIM,HSPA8,NRBF2,EEF1G,PHB2,RPL39,CUL2,PRSS1,HSP90AA1,RPS5,YWHAZ,CCT2,ATP1A3,ELK3,RAN,VDAC2,TNPO3,GNB1,POLR2B,TUBB,RBBP4,PRDX2,ATP5F1B,EEF2,RPS7,SERPINA3,H1-3,GDI2,EZH2,TUBB4B,BAG2,RUVBL2,PCNA,CCT8,HSPD1,SLC25A5,SSRP1,VDAC1,HNRNPF,HNRNPA1,XPO1,MARCHF5,STOML2,PRDX1,HSPB1,DRG1,XPO5,EED,HSP90AB1,CCT7,PPIA,CACYBP,ERLIN1,TCP1,DYNC1I2,RPS10,NTPCR,CNP,UBA52,SF3A1,PSMC4,RBFOX2,CDK1,ARPC2,PRDX6,H2BC12,BAP1,HSPA5,EIF4E,TUFM,AR,RPS17,ATP5F1A,AKT1,SLC25A1,MAT2A,HSPA14,XPOT,ATP1A1,ALB,SEC61A1,PSMC5,HEY2,ENO1,TUBA1B,UQCRC2,RPS3,VIRMA,EEF1A1,MTCH2,CCT5,PSMC3,CAPZA2,SLC16A1,GLUL,SLC25A10,FASTKD5,FARSA,KPNA2,CAMK2G,HUWE1,GAPDH,CSNK2A1,TSNAX,NME2,MTAP,AIFM1,EEF1B2,SLC25A12,TMPO,MBD5,MIF |
| 6.176e-07 | -14.30 | NONO (non-POU domain containing octamer binding) | protein interactions | 4841 | 493 | 188 | 19454 | 5460 |
NDUFS3,MIR20A,MIR17,TOPORS,CD2BP2,MIR15A,MIR200C,SOCS3,HUWE1,SMN1,ARF4,FAF1,RPL23A,ZC3H11A,ECD,MIR34A,TLE1,ORC5,HDAC6,TOP1,PLEKHF2,CDK9,MIR106B,MIR25,METTL14,CDK1,LMNA,CCND1,ATG16L1,PCK2,CDK7,MIR1-2,FBXW7,MIR7-3,PIAS1,MIR205,RPA3,MIR34C,MIRLET7I,CCDC22,MIR145,CA2,CIAO1,CD164,RALB,NONO,KPNA6,AR,PPP1CC,RUNX1,NDN,VIRMA,CTTN,MIR16-1,CCNF,TRIM24,UBE2I,GSK3A,EZH2,RBPJ,ZNF263,RAF1,UBE2A,MORC2,PCNA,FAM76B,MIR1-1,NDC80,HNRNPA1,NUP35,MIR7-2,PHB1,MIR141,TSG101,KCND3,LMO4,PPP1CB,UCHL3,MIR106A,ASB3,PSMA3,TAFAZZIN,MIR363,CUL2,CUL3,SAMHD1,PDE4B,MIR98,ACTB,MIRLET7D,DDX42,NUPR1,RNF8,H2AX,MIR16-2,MIRLET7C,MEPCE,MIR200A,MIR9-3,DHX9,SNRNP70,COX5A,COPS5,CD81,PPIL4,MIRLET7G,TMED9,CAND1,CDC5L,MIR429,CD274,WWP1,CD46,RPA2,MIR7-1,HECTD1,UBE2M,MIR21,HEXIM1,MIR34B,IGFBP3,MRPL41,HDAC3,MIR107,MIR29A,POLR1H,PML,MIR10B,BAP1,RNF113A,ZFAND6,RC3H2,SPOP,KCNJ2,RBM7,UBE2H,GORASP2,PRKACB,RALA,SRC,PPP1R10,PSPC1,SMARCB1,MIR222,MIR155,KRAS,HNRNPDL,MIR9-2,EWSR1,MIR206,MIR31,AGR2,MIR140,ARMC8,MIR221,MIR143,WWP2,DDRGK1,CTNNB1,XPO1,MIR29C,MIR9-1,SUMO2,RPS10,PEG10,SIN3A,MIR214,EED,UBAC2,PIH1D1,NUFIP2,MTF1,STAU1,FXR2,UFL1,SNRPA,DDX39B,DDX5,EP300,HDAC5,HSPA8,SFN,CREBBP,MYC,BTF3,MATR3,MIRLET7B,PRMT5 |
| 6.204e-07 | -14.29 | SF3A2 (splicing factor 3a subunit 2) | protein interactions | 8175 | 258 | 109 | 19454 | 5460 |
BUD31,SNRPA1,SNRPD3,CCAR2,TRIR,DHX15,SRSF1,RBM5,PRCC,DDX23,SKIC8,PSMD3,PRPF19,HNRNPA1,ZNF207,CCAR1,SRSF4,TFG,HSPD1,ARGLU1,HNRNPA2B1,RBM3,SRSF7,BAG2,SMNDC1,SF3B5,SNRPE,ISG15,SNRNP40,ERH,SNRPB2,ESR2,SNRPD1,SF3B4,SNRPD2,CIRBP,PSMD14,RIT1,NLRP3,MYC,HNRNPC,CFAP20,CUL3,HNRNPAB,PRPF31,SNRPB,TTC33,TRA2B,SRSF2,UFL1,SAP18,SNRPA,DDX39B,SLU7,NKAPD1,HSPA8,SF3B1,DDX5,EP300,USP39,AGGF1,MFAP1,PSRC1,CSNK1A1,NCBP2,CDC5L,CWC15,SYNCRIP,ALYREF,SNRNP70,RBM17,TPM3,API5,LSM4,CDC40,CTNNBL1,HNRNPK,THRAP3,RIGI,SNRPG,SNIP1,PQBP1,HAPSTR1,EMC2,DHX9,DDX42,ILF2,TP53,WBP11,CD2BP2,MAP1LC3B,BUB3,SF3B6,EIF4A3,UBE2H,SUGP1,DNAJC8,RBM22,DDX46,RPA3,PRPF4,RPA2,TFIP11,SAP30BP,RETN,SF3A1,PPP1R8,SNRPN,CDC42 |
| 6.204e-07 | -14.29 | MTNAP1 (mitochondrial nucleoid associated protein 1) | protein interactions | 55028 | 258 | 109 | 19454 | 5460 |
NDUFS3,MRPL49,GFM2,MRPL47,NDUFA2,MRPL11,ATP5PB,METTL15,AURKAIP1,MRPS33,FKBP8,FASTKD5,ATP5PF,HSD17B10,MRPS18B,TMEM70,CHCHD1,COX5A,GRSF1,TOP1,MRPS23,MRPL24,ATP5PD,DBT,MALSU1,COX4I1,MRPS9,AIFM1,SSBP1,GOLGA5,MRPS34,MTRES1,MRPL41,YKT6,PDHB,NME4,CRYZ,MRPL20,POLDIP2,DLAT,GFM1,MRPS16,DNAJC19,OAT,PYCR2,NDUFAF2,TUFM,PSPC1,PTPMT1,ACAT1,MRPS28,NDUFS6,PDHA1,NDUFA12,ETFB,FAF2,ETFA,ATP5F1D,KGD4,USP30,HNRNPDL,IMMP2L,MRPS17,SRSF4,HSPD1,COX8A,HINT2,RHOG,MRPS26,MRPS35,STOML2,CLPX,MTRF1,NDUFV2,NDUFS8,PNPLA8,SDC4,PHB1,GATD3,YBEY,NDUFA5,TOR1AIP2,PTAR1,NDUFAF3,MRPL12,PHB2,NDUFS2,HSCB,MRPS7,EXD2,NGRN,AKAP1,HADHA,MRPS25,HNRNPAB,PMPCA,PYCR1,AUH,MTG2,MRPL23,PARL,NDUFAF4,GPR37,MTG1,DLST,CCDC90B,TACO1,CD79B,MRPL13 |
| 6.244e-07 | -14.29 | membrane | cellular component | GO:0016020 | 9220 | 2832 | 19108 | 5553 |
TMEM60,ROCK1,RHBG,EIF2S1,NUDT1,SCN1B,ADCK1,PAK2,F2,RXFP2,CRHR1,ICAM2,CXCL12,PCDHB8,SNX12,AJM1,UBAP1,SURF4,DHX9,NPY5R,MAP1LC3A,PIP5K1A,TMED7,GRM2,HIGD1C,TMEM174,DNAJC30,KRIT1,NDUFS3,CIBAR1,NECTIN2,SEMA3C,PPP2R1A,HAX1,ARMCX3,NDUFAF3,PROM1,DDRGK1,FRRS1L,TAS2R13,RHOB,GNPTG,CDK5R1,OTULINL,HTR1F,FCGR1A,PDE9A,LAMP3,VPS4A,LIMD2,ARHGAP1,MICB,VPS39,UST,ARHGEF39,LDB2,FCMR,FAM241A,GDE1,RPL9,PTPN5,RPS20,SELENOS,LCP1,LRRC8A,WDR45,DUSP21,YWHAH,TMEM106C,VSIR,RAC2,KLHL7,DPM2,TAS2R5,PAFAH1B3,FAM83B,PAQR3,SGMS1,OSBPL8,RHEB,ADIG,CHRNB2,INPP4A,GPNMB,MARVELD1,DLG3,VPS33A,GLRA2,CMKLR2,MAP1LC3B,EMC2,EFNA5,PLEKHO1,MANBAL,MRPL40,TMBIM1,TNFSF13,DNAJC10,IMMP2L,CKB,SLCO1A2,STOM,UBE2D3,GPR34,CPT1B,CSGALNACT1,SEMA7A,JAGN1,OR2F1,CD226,CAV3,REEP3,MTX2,SMCP,PIK3CG,SLC25A39,PRSS8,LANCL1,TMEM177,PYURF,YIF1A,NRN1,KDELR2,SLC25A51,CREB3L4,TAS2R7,SV2B,EIF4A3,PSMD10,CHST7,CTSK,SLC6A7,C1QTNF1,TMIGD3,GPR83,IFI35,FAM241B,EFNA3,OR10G9,RAP2A,SLC39A3,RELL1,GPSM3,RAB3C,CATSPERZ,EXOC8,SPTSSA,P2RY1,TLR1,VAMP3,OR10Q1,OR10A7,MRPS11,DMPK,PRCP,ENO2,ACTL9,AIG1,LEPROTL1,SAR1B,TMEM256,HSDL2,PIK3R2,DRG2,PCDHA5,MFSD6L,CNTN2,CLDN8,RAB28,STT3A,EMC6,CPSF2,RPS4X,CIDEB,RILPL2,GABRG2,MYORG,FAM187B,LRP10,STK26,GPR22,CD209,PRDX3,GXYLT2,NONO,SMIM13,GPR37L1,PRNP,FAM210A,EPS8,PCDHB1,ABHD13,BCL10,TIMM8B,CYTH2,FRMD8,TAS2R40,CLVS1,SLC5A6,IGF1,TRIM36,TMEM179B,ORAI3,RETREG3,GGT7,TSPAN7,OR4K1,NFE2L2,EEF1A1,PIK3CA,RGMB,RAB11A,TUBB,TMEM176A,STBD1,CBX3,SLC6A2,POPDC2,PSEN2,HAS3,FLRT3,USP14,ILVBL,PML,TMUB1,CCDC167,CTXN2,KARS1,KRR1,COX6B2,STUM,SPRN,PALS2,MRPL57,TMEM170B,CYP4F12,GPAM,PLPP4,SLC39A10,DNAJC25,ARHGAP25,PAFAH1B1,OR6C4,ARPC2,ATP5MG,OR52W1,PDE6A,ARPC3,TMEM164,GCA,TNFRSF14,TWNK,WSCD1,CEND1,BIRC2,ADGRL3,ASTN1,ASPM,MAPRE1,NCAPG2,NLRP3,SLC66A2,CD52,ADGRG1,RAB5A,VSTM4,OR4A47,OR10A6,OR13A1,SESTD1,TMEM213,EIF3D,ALG2,GNB3,SMIM11,MRPL47,CCR3,TRIM27,FBP2,TMEM19,SLC1A3,RNF139,NTN4,CYBRD1,NGRN,LRP6,COQ10B,LBR,TMEM126B,CRELD1,ATP6V1C1,TMEM114,ALKAL1,TIMM21,ENTPD3,BAG3,RETREG1,BST2,HEXB,FLRT2,AQP4,RNF141,CACNB4,SCG3,GCNT3,MRPL36,CYP11B1,GNG12,GALNT1,TMEM33,F7,CALY,UQCRC2,TAPBP,CEACAM5,PTN,NAA35,GAPT,ARMC1,ILF2,ARHGAP5,NDUFB7,SEC61G,DPP10,NINJ1,ST3GAL5,ELOVL7,TBC1D13,ST8SIA4,CHMP4C,SNX10,CCDC25,TFRC,ITGB5,HBA1,PSME2,TRAF7,NPTN,TMEM100,CDH13,GAS8,PYCARD,CLEC2B,GNG13,BNIP3L,MAVS,ARHGAP15,FHIT,FAM8A1,EIF2AK2,PXMP2,PDIA3,RAPGEF5,CNTFR,NDUFC2,STARD7,PAFAH1B2,CYP17A1,IL13,GLIPR1,DBH,DHRS13,MRPL34,NUFIP2,FARSA,TMT1B,GNGT2,SYK,SFTPD,GRID1,AP2S1,LILRA2,FXR2,PIK3R3,HCLS1,TAMM41,RAN,FKTN,KLF9,SWAP70,ATP6V1D,CNRIP1,OR5K1,LYNX1,MCM3,LMNB1,PHKB,NAPA,BAX,CLEC6A,ASIC2,CTSB,LRP12,MARCKSL1,PDIA6,TMEM268,PTP4A2,FCGR2B,CCND1,HSPA13,EFCAB7,MRPL12,MITF,CYP27A1,MRPL49,DNAJB6,KRAS,COX10,RASD1,MGMT,IZUMO2,RGMA,OR9K2,GNPNAT1,ERVV-2,LAPTM4A,RALA,SERPINA5,PSMC4,AGPAT1,PTPRZ1,TMEM87A,SGMS2,CXCL10,SNTA1,SLC7A11,DCAKD,CACNB2,PPM1B,CD40LG,SLC25A12,ITGA6,HILPDA,GPR171,EXTL2,ATP1A1,MAP1B,AKR1A1,GANAB,PEX26,GYS1,PEX13,CX3CL1,STX8,GPR89A,CHMP2B,MFSD3,ZDHHC14,SHISAL2B,DIPK1A,ARHGAP21,MTMR2,EMC8,TMEM59L,CTSA,DPP4,MLF2,FADS2,RIGI,IFNAR1,NECAP1,VKORC1L1,CLPX,TMEM106B,TAB2,PGR,OST4,SLC6A1,BMPR1A,CALHM2,FAR2,ABHD17A,LYSET,RPS27A,RPL4,RETSAT,TBC1D24,PLEKHF1,RAB8B,KHDC1,LILRA3,MAP2K1,RPS2,TMEM243,OR2J3,RNF167,TMED3,CTNNA1,CTSD,GCC1,OR52M1,SMCO3,VTA1,TLR8,FKBP1A,RPL32,NECAP2,ING2,TMCC2,CH25H,VIPAS39,DUOXA2,MYO1B,KCNG3,B3GALNT1,RPS11,TPBG,PTPN4,SOCS2,RALB,VXN,TMEM156,TMEM74B,HIGD2A,STX16,ODR4,MAP2K3,TCTA,CHID1,MED17,SLC39A7,PRPF19,HMOX2,TMEM14A,SEPTIN7,RNF128,LDLRAD4,H2BC11,OLR1,OR8B12,OR9I1,ELMOD2,GOLGA7B,DHRS7B,PSMB2,FKBP2,HACD1,HSPA5,DNAJC5,IFI27,PDLIM4,SSMEM1,PTGFR,FGFBP1,CPTP,CLDND1,JAKMIP1,ARMCX1,ARL14EP,FUBP3,COX6C,CYP2F1,SHISA2,XRCC5,RHOU,TRAF1,GALNT2,RER1,USE1,FMO2,LHFPL2,RPL29,TMEM108,VAMP1,PI3,FGR,WASL,MARCHF9,MDM2,MLC1,NIPA2,CYP3A43,EIF4EBP3,ARHGAP19,AURKAIP1,SPCS2,ZBED1,ST8SIA5,CHST11,ACP5,STXBP1,PTPMT1,GGCX,CHRM4,OR14J1,PMAIP1,ZMYND19,EXT1,KIF3B,CCDC47,SEPTIN6,TMEM254,RAB13,SCAMP2,TFEB,SLITRK1,AQP3,SSR2,ATP5MC3,CLDN14,BAK1,BRI3,MTARC2,SLC25A5,PPP1R16A,NRBF2,ADTRP,ARL6IP5,RAB31,OSBP,RDH12,SYNGR1,HPS6,RPL13A,UTS2R,GOSR1,FGF10,CCDC90B,GRIA1,RNF103,MT3,CYP3A5,TNR,MRPS7,MRPS17,PTGER2,TAS2R46,AAMP,PTPRQ,VEGFA,TOMM70,COX14,ANXA7,EEF2,SFXN2,IFI16,ARL6,NRSN2,KCND2,ZNRF1,P2RY4,OR6X1,TMEM184C,RGS7BP,CAMK2G,BORCS7,ST3GAL2,SDHC,PHB1,RHOBTB1,TEX264,RPL28,ZBTB33,PPP4C,MSN,GNRHR2,CASC3,ADD1,FUT9,CPEB1,TTPAL,ESYT1,ARL4D,CD9,GPR176,HARBI1,CNNM4,TRAF3IP2,CLDN4,TUBA1A,SYPL1,RABIF,TMEM219,SLCO2B1,TESC,LY6G5C,PRKD3,OR1F1,MINAR1,CCDC32,TNFSF18,FDFT1,IL20RB,CHPF,PSMC1,KLRF1,EMC10,AIP,HSD17B3,BLOC1S2,RIMS3,FATE1,SHC1,KPNA6,CCDC134,RPS7,PLA2G15,RGP1,IFI6,EFHD1,SUSD6,IL2RB,SMURF1,MRPS33,SPTBN1,LDLR,AP1S2,TMEM31,HPCA,NDUFA5,RPL35A,UBL4A,PSMD3,CD247,S100A8,TAB1,CYB5R1,NLRP6,RIT2,MRPL20,DIPK2A,OMG,PPIA,SELENOI,MGAT1,TMEM255A,FAM20B,SMIM19,KCNJ8,TOM1L2,CEP41,NCR3,AP1M1,POMP,SNX18,CNIH4,RASGEF1C,CALR,SERPINH1,CD83,CD1B,PRICKLE2,ATF4,CSE1L,SIT1,MRPS35,PIP4P1,IL6,SLC30A5,EMC9,PALM2AKAP2,DIO3,POPDC3,SPRED1,SLC25A42,SLC25A27,GLT8D2,GJA10,MRPL41,SYNGR4,MYL6,TMEM91,RIT1,DRAM1,LRRC4,CDH7,NF2,FAF1,IL1R2,KCNJ10,B3GALT1,GNAO1,SLC2A8,CAPZA2,SH3BGRL,TOMM22,WDR3,HNRNPC,CLIC2,GLIPR2,HNRNPH2,DPAGT1,SLC13A5,B9D2,RPS28,B4GALT3,RPL6,ALG5,ANO3,TSPAN3,CD200R1,SYNPR,STC1,RPLP2,FGFR1,CD200,TMEM176B,MRPL9,GOLPH3L,CAVIN2,OR4D9,COX8A,PRKRA,GOLGA7,GPR146,DAD1,CXCL9,RAF1,OR1S1,METTL25B,TAS1R2,TLR6,GPR173,ROMO1,OR8I2,TMEM45A,MRPL52,S1PR4,CD248,COX4I2,PPIB,TMED5,CORO1C,PPIF,LPAR1,VPS4B,PLPP6,TF,MX2,HSD11B1,GJB2,ATP6V0E1,SLC2A3,TMEM208,ST6GALNAC3,TMEM127,SERPINB1,CD34,LITAF,ZBED3,GALNT4,SLC35F2,LHFPL4,CNTNAP1,NCK1,TMED1,HACD3,ABCG2,ATP5PO,BBS5,OR1M1,GALNT17,CYB5B,OR10G2,YWHAB,VDAC1,PIGY,TMEM50B,TRAPPC4,KCNB1,KLRC2,CYP27B1,B9D1,KCNAB1,ZDHHC17,ST6GAL1,DNAJB2,EEIG1,TSPAN18,IFNGR1,ATP1A3,AZIN2,DECR2,BICD2,FKBP10,LRRC4B,TYROBP,FTH1,RANGRF,ENHO,CFAP95,TNF,PITPNB,RPL7,RGS2,MRPL23,PEX3,SLC25A31,TMEM203,OAS1,CHDH,TMEM204,GAL3ST1,BCS1L,WWP1,SLC8A1,STX10,TMEM205,LEPR,STX5,ACVR1C,VAV2,CHRM3,MAIP1,RAB3D,SNX17,LRRTM1,SLCO1B3,TSPAN5,LY96,GNG2,PRND,OR51A4,SNX22,TMEM70,GORASP2,WTAP,SLC29A1,SNX2,SRI,OR2D3,MRC1,SLC7A14,NPSR1,SERPINB6,RB1CC1,PCMTD1,KDSR,RPS13,MINAR2,TMEM97,RGL1,NDUFA1,CPE,HOMER3,PNPLA8,LGALS3,PLA2G5,SLC41A3,CHCHD6,RAB6B,GABARAP,UNC50,C1GALT1C1,RAB29,PDCD10,RPL10L,GAD2,ARFGAP1,HSD17B10,ELOVL4,GASK1B,TMEM89,MSMO1,CYP39A1,SYS1,LAMTOR2,TLR7,ST3GAL4,TOR1B,EMC4,CTNND1,OR51E2,PLCB1,NOC4L,ELK1,B4GALT6,FABP5,LRRC8B,CNR1,FITM1,GNAI2,MRPL16,JAK1,LMBRD1,ABHD2,CRAT,VPS16,B4GALT7,ZBTB42,RAB37,LEMD3,GNG10,RPL26,HOMER1,TM2D2,OR2Y1,COX4I1,ENTPD4,FAM168B,SH3BP4,CALHM5,NCSTN,GHR,UBAC2,NOS1AP,LRRC24,SLC16A4,GPIHBP1,DEFB1,FXYD6,TCAF2,QTRT2,COX5A,VAMP5,PRKAG1,TRMT10B,XXYLT1,CARD19,EHD1,KCNJ3,PLP2,B4GAT1,SLC15A2,EXOC3,LGR4,NDUFAB1,ATXN10,NPBWR1,ATP1B1,METAP2,LAMP2,TMOD1,RASL12,OR5L1,CYC1,WDR83OS,STX18,SLC23A2,PRRC2A,IGSF21,TRAM1,PRDX6,BSCL2,GPR75,CNKSR3,CLRN2,UQCC6,OCEL1,FA2H,IKBKB,SFRP1,GOLGA5,CAV2,JOSD1,CHST9,PRSS12,SPCS1,PTGER1,SLC12A2,ATP5MC1,PNOC,NAIF1,TLCD1,ANXA4,VAMP2,SOCS5,AQP2,RPL19,TOMM40L,NCR3LG1,ACTR2,SVOP,KCND3,HS3ST5,MINDY3,RNF40,TICAM2,GPR85,FAM107A,DPEP1,MTG1,FZD4,TMEM196,HDAC6,SLC25A11,MRPS28,MX1,PHKA1,MRPS25,PACSIN3,HADHA,TNFAIP8L3,SCYL2,SLC6A11,RARS1,TOM1L1,CD47,MTA2,NPY1R,TMEM237,SUV39H1,CLDN6,RRAGB,EDC3,TNFRSF1B,NAA60,PDE4B,FCAR,FASLG,ERLIN1,SLC4A10,AP2A1,CDC42EP3,NETO2,ALYREF,HYCC1,TMEM81,CBLN1,TMIGD1,CAMKV,MRPL10,TMX2,RPS24,OR10P1,CUTA,OPRL1,SLC6A6,ORC6,TFPI,LRRC40,ENDOD1,LTA,TLR9,ADAM21,CLDN1,LIMS2,HM13,TMEM126A,PSMD12,TMEM170A,TMEM50A,MRPL24,SLCO3A1,STOML2,ENO1,ITPRIPL2,CDIP1,CRKL,FIS1,ATP2B4,GRM1,SEC61A2,NTRK2,HNRNPK,TMEM117,STAT2,CFAP418,TMEM165,SLITRK5,MAN1A2,TBC1D10C,ENPEP,HDAC3,TRAK2,TMEM42,TLR3,IL6ST,SDF2L1,PSMD7,CYTH4,SLC1A1,TICAM1,XBP1,GPHN,STX17,SSPN,TMEM107,NDC80,LDHA,FRZB,TEX261,GRAP,LILRA1,CD86,PPP2R5A,PLPPR1,PDE6D,STX6,BLCAP,ERAS,TMEM191C,PARL,DEGS1,MRGPRX2,HHIP,EMILIN1,ORAI2,TNPO3,SLC6A12,RHCE,RAP2B,NEGR1,SRPRA,DRD3,RPL10,RPS23,TOLLIP,LANCL2,SNAP29,KCNA2,NDUFB4,S100A10,RASGRP3,DKK1,P3H1,ZFAND2B,SLC25A1,TOMM20,ADD2,ARF4,CD14,GLUL,F11R,MGAT4B,CYP2R1,BRCA1,SNN,SPRY1,DLG4,TMBIM6,CAMLG,GLRA1,CHMP1A,FIG4,ERVV-1,OR2A25,NIBAN2,ATAD1,TNFSF12,OR2H2,WBP1L,TMEM184B,PCDH17,RPL12,CD4,DNAJB9,TSPAN17,LPCAT3,GPR162,DLK2,MEST,STMN2,FAM20C,PLEKHA8,SLC20A1,CD1C,TNIK,CCR6,CXCR1,KCTD3,SLC37A4,STK24,TLR4,MCHR1,TRAPPC14,RMDN3,AKT1,SLC38A9,ICAM1,RPRML,ERG28,TSPO,PTP4A3,CHST13,VPS54,SLC39A9,UBA52,TASL,ARFGAP3,LHFPL6,TNFSF8,ARHGAP12,DYNLL1,TNFRSF9,CIB2,EHD4,EIF3K,DDX5,RAB9B,TSHR,CD40,NUF2,TRAM1L1,PREB,OR4S2,CTTN,SPINT2,TMEM115,GRAP2,RPL7A,TM9SF4,RAP2C,FAM174A,TIMMDC1,MFSD6,ENPP4,HPCAL1,AP5M1,CD59,SERTM1,SPEM1,SLAMF9,MTCH2,KCNK13,KLHDC8B,NDUFB8,SEPHS1,GNPAT,RNF133,MAP3K11,IL12B,GNG7,TOMM40,DUSP3,TLCD3B,HEXA,ATG16L1,FEN1,RAB3A,TMEM220,CLEC1A,SLC35A1,SPEF1,MANSC1,ZYX,PIANP,ITGB8,WEE2,RP2,CHIC2,MUL1,OR4B1,TTC1,MOB4,SERPINB9,SLC38A1,CYRIA,NDUFB10,CDK5,ECRG4,SLC38A7,PHTF2,TMEM198,RAB1B,CDK5RAP3,STK38L,UFD1,VPS18,AKAP12,CYSTM1,B4GALT1,RNF34,UGT2A3,CD164,ACVR1,CDC5L,AKT3,INSIG2,TSPO2,SLC30A7,TMEM229B,DNAJC19,TAS2R39,KICS2,CDC42EP4,KIF2A,SLC25A17,PRKCQ,AFAP1L2,TOR1AIP2,TOMM7,ANKH,CNTN1,TMEM94,PSEN1,GABARAPL2,STX7,ABHD6,CSNK1G3,PTPN22,TRPC1,CCNY,LY6H,COA1,NAE1,AIFM1,NHERF1,ATP5PD,ARFIP1,LRRN1,NUP107,LTB,CYRIB,CEBPE,BORCS8,CYP1B1,FCHO2,NCDN,BAALC,RAB18,SLC35E3,CYB5R3,LRAT,RNF121,EPHA4,UBE2B,BCL2A1,GABRA2,FANCG,CACNB3,FAM200A,CATIP,CYP21A2,RPS16,SNX5,NDUFAF6,KDELR1,EHD3,TACR3,SLC48A1,MARS1,SDC4,UBL3,YIPF4,P2RY10,DDX39A,DRP2,PIGA,SLC52A3,RAB33A,PROS1,NOSIP,ICOS,PEX5L,HCST,NLGN2,CLDN24,TSPAN11,IL1RAP,CLEC7A,MIA2,NUP50,CMTM7,TMX3,SNX1,CD151,MME,OR5AN1,CD3G,STARD3NL,NDFIP1,YIPF3,SMIM12,TECR,TLCD4,OR51S1,GLE1,SELENON,SSNA1,MAD2L1BP,HBEGF,MGST2,BAD,JPT2,FMO1,LRRC8C,KCNC1,SYT4,RPS15,TMEM252,HMGB1,APBB3,SDR16C5,PPFIA2,DIRAS2,RETREG2,SYNJ2BP,MOSPD1,STYK1,AP2M1,ELMO2,CTNNB1,PTGER4,MPV17,SNAP23,CERS6,ATG9A,VEGFC,IRF7,RINT1,MCL1,SC5D,ASIC1,ILK,IQSEC1,SNAPIN,DDR1,TMEM45B,WDR6,H3C1,CASP4,SIGLEC5,GJB1,PGAM1,EPCAM,MPDU1,TMEM215,SSR3,DHRS7,SLA2,TOM1,CTSC,REN,TLR10,KCNJ2,RGS6,STAU1,GLO1,RBMX2,TIMM8A,BZW2,ASB3,RCE1,STK16,SOD1,MAMDC2,CD28,DIO2,PAQR4,RPL35,NUP62,SLC18B1,MPV17L2,BECN1,NME1,CYFIP2,BORCS5,VSTM2A,MED4,ACKR3,PDYN,OR8H3,KRT8,RPS9,PNPLA4,GNAQ,RPS14,API5,MGST3,ORMDL1,VAMP8,SLC25A14,PLN,TESPA1,LYPD6,SAYSD1,CDH8,TMED9,TMEM231,FZD6,USP30,EIF3E,EXOC1,PIK3AP1,GJC1,CSGALNACT2,MPZ,SLC7A1,TMEM263,YIPF5,SLC25A3,PIGK,RPS29,UQCRQ,RABGGTB,CDK1,FZR1,SESN2,SVIP,CLCA1,SLC25A26,CD63,SEC61B,LILRB4,MPIG6B,CMTM6,RTP4,OR10A4,HACD4,CLIC4,KLC2,RNF26,STAC3,AP5S1,CHMP5,CTLA4,MARCHF5,CNP,HS3ST3A1,PPT1,RAB11B,REEP4,EDNRA,MGAT5B,EMC1,CFC1,ATP5F1A,PSMD1,CACNG3,HRH2,FGF13,ILDR1,CD99L2,OR2A2,MRPL33,RAB32,S100A6,RAB6A,LDHB,MRPS18C,DERL2,PIGW,TMT1A,RSAD2,SEC11A,DRG1,THBD,REEP6,SLC15A1,PLP1,PABPC1,TMEM101,OR4Q3,CLDN22,ELOVL3,OR5I1,LRRC8D,MOXD1,NRM,LST1,OR4M1,PGAP4,SLC45A3,OLA1,C2CD2,GABARAPL1,FUT8,SOS2,SYNGR3,COMT,ELMO1,SERINC1,RUVBL1,NTPCR,RAP1B,FERMT2,CHPF2,MOG,NCKAP1,EIF4H,BACE1,RPRM,TNKS2,IRAK4,MGARP,TMEM39A,GPR65,OR8K1,RDH10,TOPBP1,ADRB3,ABCE1,PLXNC1,USP6NL,GRIK1,STARD13,B4GALT4,OR6M1,GTF3C3,VAMP7,OR4K17,AIF1L,MAPK10,PHB2,SLC16A1,GLT8D1,SPCS3,PMPCA,CYB561D2,MRAS,GNG11,CRBN,MTG2,POLR2B,HYAL2,SLC7A8,TIMM17A,RHOJ,MTM1,NDUFA2,PSMC3,SLC38A3,FCN2,SIPA1L1,VPS26B,DNAJC4,RASL10B,TRIM23,SLC31A1,RPSA,DHX38,VPS26A,SEC61A1,LSM4,SNX24,TMC7,PPP1CC,FAF2,NAA15,SPTSSB,TMEM168,MIF,SOCS3,JADE1,GPR160,STIM1,ATP5F1E,ST7,RCCD1,JAML,PCYT1B,RPL27,LGALS8,ADCY2,CRLF3,SEC22C,IDE,B3GALT2,TAPT1,ADRM1,GDPD3,TGFBR2,TMEM106A,GAPDH,ANGPT1,ADIPOR2,DERL1,DTL,RHBDL3,SGTA,CNPPD1,TMEM160,COX20,MRPS18B,IER3,PTGDS,NDUFAF4,PLSCR3,ABCB1,P2RY11,HSD17B6,QPCTL,SUCLG2,TMEM190,RPS26,KCNS1,DXO,TRAF6,TGFB3,RPN1,CHST10,SLC7A4,MTHFD2L,CCNB1,OR4D6,COMTD1,SKAP2,COX7B,OR4K2,PICK1,CCR7,INPP5E,CNOT6,TRA2B,FNDC9,DNAL4,SLC4A8,CREB3,PTRH2,SPRED2,BFAR,CNOT7,UGT1A1,CYBC1,TBC1D5,WNT7A,OCRL,ESAM,POR,SPRR1B,LY6G6C,CD1D,CDC42SE2,CISD1,RABAC1,MRGPRX4,KXD1,CBL,KCNK10,CYTH1,AGK,GPC4,OR5A2,CDK9,OR4K13,TENM3,SLC20A2,FUT1,PDSS2,ACSL4,SCAMP5,THG1L,ADORA3,CCR5,APH1A,CHRM1,ARF1,ADK,GNB1,TMEM123,CNOT2,SFT2D2,TVP23B,HNRNPL,OR4F6,PGRMC1,RAB9A,CAP2,CD80,SERPINB10,HTRA2,STX1A,AVPR1B,SUMO1,CKLF,POMT2,CHMP2A,CHST2,MCOLN1,FUNDC1,HRAS,TIMM23,CDAN1,RHAG,NUP153,NDUFS2,NUS1,KCNH8,LAMTOR1,MFSD5,PSKH1,PEG10,NUDT9,CTXN3,RPS17,KCNMB2,RPS5,L1CAM,SLC25A44,TUSC3,ADRB1,SMAD1,SLC1A2,MIOS,IL15RA,EMP2,RNF152,UBB,PTEN,BVES,PPP1R12A,TM9SF1,OLFM3,ERRFI1,GABRB3,SLC19A3,SYBU,VIPR1,TIRAP,AFTPH,NTRK3,RAB19,GNB4,RS1,TIMM10,DNAJB4,CLEC12B,NDUFB5,MARCHF3,RERG,AP3S2,HSPA14,PSENEN,CYP4F8,RAB1A,ZDHHC8,G6PC3,VAC14,MFSD14B,MBL2,CLBA1,UGCG,SYT2,HSP90AA1,CTNNBL1,LIN7B,CYB5D2,GNG5,OR5B3,OR4D11,RHCG,PLGRKT,AGER,MYO6,GPM6A,PDCD1LG2,CX3CR1,JPH4,EI24,AMACR,WDR83,EPHA2,GABBR1,OR4E2,HFE,SAMM50,EHBP1,MRPS26,DPEP3,LRFN3,SYVN1,VSTM2L,NEU1,CDSN,FLCN,ATP5PF,RUVBL2,EIF5A2,MREG,CCR2,KGD4,PSD2,SPTAN1,CHMP1B,ACHE,LTBR,GINM1,PIGC,B2M,EPHB6,SLC25A10,VAPB,RTCB,SRD5A3,TAS2R16,BTN2A2,TFE3,SLC6A4,LRRTM2,FURIN,HSP90AB1,ERO1A,MTMR6,CAND1,TREML1,SDCBP,ATP6V1G2,AIF1,PGK1,TMUB2,SLC22A17,YKT6,LYZL6,SLC51A,HACD2,UQCC3,BORCS6,TULP3,SYNDIG1,RPGRIP1L,HSPB1,TIMM13,PCDHB13,GNA14,SLC35E1,SRPRB,RPL23,HTR5A,NR0B1,OR2AT4,KCNA3,SMCO4,NMBR,LHFPL7,PLA2G4B,CGAS,UQCC2,MAEA,COX16,MRPL51,SERINC3,FZD3,F10,ETV6,RGS10,NDST1,RACGAP1,SCN2B,DHRS3,CISH,THAP7,DAPK1,ACTB,UBIAD1,ARF6,GABRA1,UNC79,CYP2C9,CLCN6,FRS3,DNM2,OR4N5,SEMA5A,TOR4A,ELOVL6,RGS19,CLDN11,SLC22A6,IGSF11,TLR5,MRPS23,LCP2,SLC35F1,DAAM1,HTRA1,TMEM30A,SLC16A10,MYD88,GDI2,PTK7,OR10G3,BET1L,EFNB1,CYB5R4,DCTN3,HDAC11,SGIP1,SARM1,HCFC2,GOSR2,DNAJC7,SFTPA1,SLU7,SLC25A32,SLC35E4,FTL,AGTRAP,RC3H2,UBXN6,CD2,NDST3,OPRM1,CD79B,ADH1A,PCDH19,NSG1,OXTR,GCHFR,DNAJC2,NDUFS6,GAS2,TMEM182,GPC1,FUNDC2,SLC38A2,RAB14,LAMTOR3,CAPN2,GRPR,ALG11,CYP2D6,MRPL53,CLN8,ABCF1,SELL,RDH11,DNAJC22,CCR1,ADORA1,MRPL11,LRRC3,TRAM2,F9,ICA1,ADIPOR1,UQCRH,CXCR6,CLRN1,BOK,LILRB1,MCHR2,FAXC,TIMM29,CHP1,MET,NOA1,HCAR1,MYRF,TNFSF10,P2RY12,TES,RAB40AL,CALHM3,JKAMP,CYP2C8,B3GNT2,KCTD16,GPR26,RAB3B,EVA1A,CD274,BMPR1B,DLST,WDR44,TMEM14B,TLR2,OR4D5,HINT2,SMAD3,GNAZ,EXD2,SACM1L,PIK3R1,RTN4,UCP2,OR4D2,TAPBPL,RAB4A,PCSK2,C9orf72,VLDLR,SEC62,SELENOT,TSPAN15,GRB10,PTCRA,CFTR,APPBP2,CUL3,GPM6B,FAS,EDEM1,CYB5A,APLNR,RPLP0,GPR17,FAM162B,RRAS2,CDIPT,CYP7A1,WWP2,SLC32A1,NRP1,ALPL,CSNK1A1,ITK,SYNRG,APOO,ATP5F1D,SLITRK2,NOTCH2,MRPS34,USP2,HSPA8,GPR78,FAM163B,OR5M9,CSNK2B,RELL2,PAQR8,CA12,SPHK2,GRPEL2,SPPL3,GPR37,CD38,GP9,DUSP18,ATP6AP2,OPTN,RIMS4,TMEM185A,TPST1,SPG21,TMEM74,CPT2,SLC43A2,ROCK2,ELOVL1,DDX50,PTGES,GNA11,TDP1,PREP,GAL3ST4,FLOT1,TSG101,PGAP2,COG1,CDK4,DOLK,SLC6A8,DDX42,OR7E24,FCHSD2,NEO1,MOSMO,ZMPSTE24,TMEM144,COX6A2,FEZ1,DUSP22,COPZ2,EMP3,PMP22,TOMM6,CPLX3,PRKACB,CHN2,GSTK1,SCHIP1,MRGPRX3,RNF146,ABHD12,KIAA0040,SLC25A45,STK11,RAB2A,RHOG,HUWE1,SNX3,MBLAC2,RAB30,TMEM88,GXYLT1,CDC42,OR8G5,VEZT,MIEN1,TMEM199,CAV1,SCD5,CSNK2A1,TPSG1,ICAM3,UQCR11,DNAJC1,GTF2I,NOP58,H2BW1,ADCY3,CCR4,EPHX1,KCNQ5,BET1,TIAM1,ATRAID,LMAN1,AZGP1,OR5V1,CYP2C18,HTR2A,TMEM185B,SH3GLB2,LNX2,UFL1,RAB23,LRRN4CL,ZMAT3,UAP1,ARRDC3,RAB22A,GABRB2,NDUFAF2,SURF2,LARGE1,TRIQK,LPXN,PIP4P2,TLCD2,PRKCE,TMEM95,SLC17A5,GGTA1,CALU,COIL,CLVS2,TAFAZZIN,NDUFB6,SNX33,HNRNPA1,KCNMA1,RAMP3,RCVRN,ZDHHC4,UQCRC1,CLEC9A,CTXN1,RNF148,TAAR6,TERB2,HTR1A,CD58,CYP11B2,SEC22A,HSPD1,IPCEF1,GRM8,ATP5MK,CYP4F22,AMIGO1,NPY2R,MRPS18A,OR2W1,CSK,REP15,RHBDD3,OPRK1,PARM1,RP9,RFTN2,PXYLP1,NDUFS8,PDZK1IP1,SLC35B3,TCIM,SLC35A2,THY1,GRPEL1,GNG3,TMCC1,MIEF1,FAM234A,SFXN1,HYCC2,VMP1,CDK7,SLC25A20,OR13C8,ACP2,INPPL1,RNF122,TENT4A,LORICRIN,RAD21,ERVFRD-1,SLC7A9,FCER1G,SLC6A3,TMEM38B,DDX1,DIRAS3,KCNK17,LARP4B,SNAP91,MFN1,YWHAG,APEH,NCALD,SEC63,TUFM,PCYOX1L,DRD1,RASL10A,RPL8,FITM2,PAQR9,PRRT1,MACO1,ATP1B3,IZUMO1,MRLN,LPAR6,OR8B8,TNKS,CRYAB,OR51M1,ATAT1,NPR2,SNX20,OGFOD3,NPC1L1,KLK6,TMED4,FAXDC2,TMEM47,ARCN1,CPNE2,CYP4V2,APMAP,KCNMB1,MRPL18,CYP1A1,EXOC2,GPR35,CHCHD1,SDC2,GALNT12,GLRB,GPD2,RBM23,HINT1,RALGAPA2,FAM162A,NTNG2,SEMA4C,SYNCRIP,SLMAP,NDUFV2,ZDHHC16,UPK1A,CDC42SE1,PICALM,SNX14,TRAPPC3,RND2,LAMP5,MYLIP,MGAT4A,ATP1A2,NETO1,OR4N4,RNF222,ITGA2,SMIM15,GK2,USP8,AKAP1,NUP35,EFHD2,KPNA2,CD36,STAMBP,ZDHHC24,DVL2,CERK,TAAR1,GLCE,EDEM3,PTDSS1,PHF7,TMEM167B,STAMBPL1,CD81,ADH1B,SCLT1,GPBAR1,DNAJC3,SHC3,LPAR2,SDR42E1,ACVR1B,TM4SF18,DFFA,CLIP3,ABCB9,NFKBIA,SFTPC,EEF1G,ADGRE2,AGPAT5,HNRNPF,IL2RA,MRPL50,STX11,SCN3B,RNF10,CXCR4,GNAI3,SPATA25,RNASEK,LMNA,WDR19,COX6B1,SLC35D1,RPL27A,SLC22A12,B3GALT4,KCNF1,CD1E,RPS12,ARL4A,TM4SF1,FOLR2,YES1,TRIM37,BRS3,CASK,CAPN1,SLC35F6,TNFSF15,VPS28,COQ8B,AQP11,SLC41A1,SORD,ARMCX2,TM4SF20,CNIH1,STX12,MMD,TRAPPC3L,RND3,AVL9,SLC35A5,OR8B4,DES,ANKRD46,XPO1,DHRS4,LYPLA1,CTNNA2,BRAP,ARFGEF1,SYN3,GHITM,RAB5C,PRKCB,SLC25A28,SEMA6C,RAB35,CHCHD3,PPFIBP1,PEDS1,RHOBTB3,SEC13,TMEM209,DSTYK,RHOH,PRRG1,CA2,LMBR1L,RPS10,RAB27A,GPAA1,KCNH1,TMEM11,TRAF3IP3,NDUFA4,CERS2,SLC39A13,SEC23A,ATP6V1G1,PPP5C,PLD3,ZC4H2,DIO1,CD1A,JAK2,OR5AP2,CHRM5,LAT2,SRC,BMPR2,CLTRN,MRPS16,SLC25A21,PPM1G,ATL1,PCNX1,NDE1,ATP6V0B,PDE2A,MPP1,GTPBP1,CCNI,SLC22A8,ST3GAL1,CSTA,NAPG,PYGB,RAB39B,MADCAM1,ANKRA2,CDH11,INPP5K,PDCD1,MTDH,RPL18,ATP2C1,SYNE4,BPNT2,SAMHD1,SLC35C1,FKRP,RRAGA,TMEM248,FMO3,LIN7C,MAGED2,SLC11A2,CDC42EP2,RPL24,CHRDL1,BCL2L1,OSTM1,PRKCA,SIGMAR1,ALOX5AP,FKBP1B,RPL31,GPR137,IZUMO1R,WDR11,COX7B2,LRP3,SNAP25,DAG1,SLC25A24,SLC25A23,MATR3,TYMS,CXCR3,CMAS,DCUN1D3,CHRNA7,DLG1,LHFPL1,TM4SF19,FAM169A,ATG101,ERLIN2,G6PD,KCNIP3,CLDN9,GPR15,PSMC5,TMEM59,CYB561,ITGAV,COPE,TERT,SLC2A1,RIC3,ATP6V1E2,ITM2A,FAM156A,PARD6A,ATP6V1A,RNF182,CHST1,CRB3,PDAP1,PLG,ZNF397,OLFM2,NLGN1,MPC1,ADRB2,FCGR2A,SRXN1,LMBRD2,HRH3,ABCC5,CFL1,SMPD2,AP1G2,COX11,OR7D4,CCDC126,CYP26A1,KLRD1,ACTR1B,ADRA1A,TPRA1,MARCHF4,CPLX1,NDUFA12,HSPE1,TTC8,EDEM2,NMI,SLC35B4,TMX4,TSPAN10,MCM4,IRF4,ACAP2,SCFD1,RNF144B,SLC25A46,PLSCR4,HNRNPA2B1,CLU,ACTN4,STOML3,SYP,RASGRP2,AHCYL1,MRPL17,DIS3L,JUP,ALCAM,FOLR1,PKP4,NSDHL,ORMDL3,RPS3,MS4A7,KCNJ11,ATP8A1,KLHL12,PCSK9,CPNE1,AGAP2,PAK5,SNX11,MRPS9,GJA1,FRRS1,ZDHHC15,CD2AP,AR,NRSN1,EWSR1,PLAAT3,SOCS4,PLEKHF2,TMEM266,KIT,C2CD2L,SERPINC1,PLSCR1,OR10G7,TMEM147,DLGAP4,CLDN3,TMEM41A,CSF2,HGS,CLSTN3,MRGPRX1,GRIA2,CD46,NFE2L1,FGD2,ERP29,CLDN12,DIRAS1,OS9,RAB33B,IGF1R,SSR1,HS2ST1,PGAP3,LRRC57,RNF5,COQ8A,SLC19A2,NUP42,AKT2,SLC35G2,CST3,RGS5,KCNIP2,SMDT1,SDHB,RPL10A,HSP90B1,DELE1,KCTD12,ATP5F1B,MMP14,SLC25A4,TMEM183A,PPP3CA,OR4N2,RUSF1,ELAPOR2,RAP1A,ABHD4,SERPINA1,MRPS21,EDA2R,SELENOK,ABCC2,PIP4K2C,SYNGR2,BCAP29,PCDH9,ACER3,ACTL6A,VTI1B,MRPL22,ITM2B,VDAC2,CBFB,HSD17B8,PTPN1,ACOX1,RGS1,CA14,COX7A1,TACR1,CPLX2,FKBP8,MRPL13,PLS3,TRAF2,LRRTM3,ATP5PB,MAP4,PGS1,MAP3K12,NME4,INHA,ARL6IP6,MFAP3L,SEC22B,IL2RG,SH3GLB1 |
| 6.301e-07 | -14.28 | RPAP2 (RNA polymerase II associated protein 2) | protein interactions | 79871 | 157 | 73 | 19454 | 5460 |
WWP2,TNFAIP6,XPO1,MED27,MED21,TOPBP1,MED4,POLR2L,EHBP1,RPRD1A,DNM2,RXRG,KRT8,PRNP,TCP1,POLR2I,PLEKHF2,KIF3B,HNRNPL,ASNSD1,EGLN3,MED9,CCT5,SPRR1B,DXO,POLR2C,POLR2G,POLR2D,FAM168A,RPAP3,RUVBL2,CPNE2,DNAAF10,KRAS,G3BP1,PDRG1,GTF3C3,CIAO1,MED22,LMO2,PPP1CC,RUNX1,PRPF31,BRCA1,MYO6,MED10,POLR1B,PFDN6,PFDN2,CCNF,POLR2F,POLR3H,POLR3B,MED17,ACTB,EIF4A2,POLR2B,MED30,POLR1D,WWP1,ARMCX3,RPRD1B,MED31,PIH1D1,PDCL,RPA3,RFC4,HELLS,EP300,MED13L,SQSTM1,FBXW7,POLR1H |
| 6.301e-07 | -14.28 | KRT10 (keratin 10) | protein interactions | 3858 | 157 | 73 | 19454 | 5460 |
SRC,VIRMA,KCTD9,NDN,UBASH3B,ALB,AP2M1,EIF4A3,RNF208,ARF1,PRSS1,UBE2H,RC3H2,BTF3,CUL2,SFN,CUL3,MYC,AKT1,PIAS1,FBXL4,PIK3R2,ADRB2,UFL1,CRY1,NMRAL1,BAP1,INPPL1,MME,DDX39B,PIH1D1,WTAP,HEXIM1,METTL14,CFTR,CDK9,MDM2,KCTD10,DCUN1D1,CAND1,ARL4D,PHB1,ARL10,EFNA3,SMAD3,MAGOH,CBL,POU5F1,AGR2,SHC1,TRAF6,DDRGK1,HNRNPA1,COPS5,HDAC6,EMC4,DIRAS2,DPP4,MEPCE,TRIM37,TNF,NEDD8,FAF1,RNF8,GLE1,EZH2,SNAPIN,DDX39A,MAP1LC3B,TP53,INSIG2,FBP1,KBTBD4 |
| 6.387e-07 | -14.26 | GTF3C1 (general transcription factor IIIC subunit 1) | protein interactions | 2975 | 221 | 96 | 19454 | 5460 |
SRSF7,UBE3A,CHCHD2,ASF1A,RPL28,GTF3C3,PAX6,CSNK1E,PNMA5,SUPT5H,MAPK10,NCSTN,SOX2,EZH2,PNMA2,CPE,MOB3C,RHOBTB1,FBXO32,SDC4,PHB1,EED,HNRNPL,SNRPA1,SUMO2,EGLN3,DHX15,UBXN6,ZCCHC10,WWP2,DDRGK1,HIRA,EP300,UFL1,TRIM52,COIL,SAP18,RPL27A,SYK,AGTRAP,USP39,SDC2,TBC1D17,ZMYM2,POLR2F,MATR3,FBXO22,APEX1,MAD2L2,MYC,CUL3,ZNF668,PSKH1,HTRA2,SEPTIN7,H3C1,CRYBA4,PTGES3,MDC1,H2AX,AURKAIP1,CBX3,CDK8,MAGEA4,EEF1AKMT3,RCHY1,FZR1,TOP1,STX6,H2AC4,SNRNP70,RPS2,BRD3,RBM23,BAP1,RPA3,SIRT7,RNF113A,FBXW7,RPL4,CCND1,EDF1,IGFBP3,GTF3C4,KLF12,CDK7,RPA2,CCNF,UBN1,ZNF330,FGFBP1,MACROH2A1,VIRMA,SUB1,ZBTB38,DEDD |
| 6.424e-07 | -14.26 | Golgi apparatus | cellular component | GO:0005794 | 1645 | 565 | 19108 | 5553 |
MAPRE1,RAB37,TMEM30A,GOSR1,JAKMIP2,GDI2,TNKS,RAB1B,PLSCR1,RGS19,OSBP,FAM91A1,B4GALT7,WSCD1,SEC14L1,DNM2,B4GALT6,CHIC2,TRAPPC2L,RP2,SERPINB9,MOB4,RAB31,GLT8D1,UBIAD1,NCALD,VAMP7,SLPI,ARF6,TLR7,USP6NL,NDST1,SCAMP2,ST3GAL4,B4GALT4,RAB13,F10,SERINC3,GASK1B,DCLRE1C,MANSC1,SELENOM,SIX5,CD2AP,ZDHHC15,SYS1,GJA1,EXT1,SLC35A1,TNKS2,GAD2,BACE1,PDCD10,ARFGAP1,CCDC186,INPPL1,CHPF2,UNC50,ATP8A1,RNF133,MS4A7,HAS3,PCSK9,PSEN2,TENT4A,TLCD3B,CHST11,RAB29,C1GALT1C1,RNF122,ST8SIA5,SLC35E1,NFE2L2,FOLR1,PLA2G5,MARCHF9,BCL6,FUT8,GABARAPL1,RNF115,GABARAP,RAB6B,RAB11A,CD59,PGAP4,SLC35A2,CPE,TRAPPC6B,TM9SF4,YKT6,CLU,CLVS1,LST1,TCP1,CYTH2,SLC35B3,PARM1,GORASP2,PRNP,SCFD1,TMEM115,PXYLP1,CTTN,VRK1,RSAD2,RHOU,STK26,SLC35B4,GALNT2,RER1,HS3ST1,MARCHF4,SNX17,TRIM22,RAB6A,FURIN,CIDEB,TREML1,ARL5B,CAND1,ERO1A,SLC39A9,VPS54,CPTP,NPY,CHST13,STX5,RNF148,AP1G2,ABCC5,LAP3,RAB32,ARFGAP3,VAPB,STX10,ADRB2,NLGN1,RAB11B,GOLGA7B,DUSP26,DNAJC5,TAS2R16,ZDHHC4,ALKBH5,MGAT5B,SH3GLB1,NOSIP,PROS1,SEC22B,PICK1,TLR2,AP1S2,LDLR,WDR44,LUM,B3GNT2,TMEM167B,PHF7,RAB33A,CHST10,FMOD,RAB3B,QPCTL,MYRF,IFT57,KDELR1,TICAM2,YIPF4,NSFL1C,RGP1,SDC4,PYCARD,ZDHHC24,GAS8,PRELP,GLCE,HS3ST5,VAMP2,SLC35E3,CHPF,ITM2B,AQP2,LGI1,CHP1,PTGDS,RNF121,PTHLH,CD36,LHB,CHST9,ST3GAL5,ST8SIA4,RAB18,VTI1B,BOK,ACER3,ARFIP1,ICA1,GOLGA5,F9,KPNA2,CAV2,SELENOK,SERPINA1,B3GALT2,TRAPPC3,GALNT1,F7,PICALM,STX18,FUT9,MGAT4A,GAPT,TAPBP,PSEN1,ZDHHC16,RAB14,BST2,RETREG1,GABARAPL2,CAPN2,MMP14,GCNT3,ST3GAL2,GPC1,SDC2,AGTRAP,SLC35E4,CLEC18A,FBXW7,NSG1,OPRM1,NDST3,GALNT12,CD2,G2E3,NAA11,CREG2,B4GAT1,GOSR2,VEGFA,LRP6,TRIM23,CST3,SLC35G2,EXOC3,PGAP3,HS2ST1,BEND5,COMMD9,ARCN1,SLC30A7,BET1L,SOST,DEFB1,FGD2,RAB33B,TMED4,VAMP5,LYPLA2,OGN,B4GALT1,NCSTN,CLSTN3,SLC66A2,NLRP3,TRAPPC6A,SOD3,HYAL2,ATAT1,ENTPD4,SGMS1,MOSMO,GOLPH3L,AP1AR,GPR89A,PAQR3,PLD3,STX8,GOLGA7,COPZ2,FEZ1,PSKH1,GANAB,COG1,PLEKHJ1,SLA2,NEO1,CYTH4,SLC39A13,SEC23A,BGLAP,HDAC3,B4GALT3,RAB27A,PGAP2,TLR3,ATP1A1,GAL3ST4,TRAF3IP3,TMEM165,HRAS,TMEM45B,TMEM209,CD40LG,MAN1A2,FAM241A,ASIC1,SGMS2,NLRP2,SPG21,FCMR,RAB9A,TMEM87A,MCOLN1,CHST2,RHOBTB3,GLIPR2,SNAPIN,AVPR1B,ARFGEF1,OPTN,ATP6AP2,B3GALT1,ATG9A,TVP23B,TPST1,UST,FUT1,SLC35A5,GNPNAT1,SPPL3,LAPTM4A,ARF1,APH1A,SCAMP5,BMP1,MMD,GPC4,PDE9A,PLAGL1,CNIH1,STX12,GLT8D2,MOSPD1,PAQR8,RND3,TRAPPC3L,TLR9,SPP1,SYT4,CYTH1,VCPIP1,PRMT5,SYNRG,APOO,KRAS,NOTCH2,CBL,FAM3C,TPPP,CDIPT,RRAS2,BARX2,CAMSAP2,GNPTG,OCIAD2,RABAC1,SLC30A5,YES1,WNT7A,OCRL,YIPF3,SLC35D1,WDR77,TBC1D5,SRGN,RPS12,CUL3,CD1E,CD1B,B3GALT4,MME,GNAI3,FAM20B,NDFIP1,AP2A1,AP1M1,RNASEK,TMED7,SNX1,MGAT1,ATP6V1D,STX11,TRIM3,SURF4,SACM1L,CLIP3,F2,TAPBPL,CREB3,NAA60,FKTN,SELENOI,DIPK2A,PIK3R1,KIF1C,CD247,INPP5E,FGF7,ROCK1,TOM1L1,RIT2,PHETA2,SCYL2,CHST1,TRAPPC14,ACHE,LTBR,ATP6V1A,CRHBP,B2M,PPT1,GAL3ST1,HS3ST3A1,CD1C,GGTA1,PITPNB,PLEKHA8,RNF128,PREPL,CXCL14,RIC3,CTLA4,STK24,CLVS2,LDLRAD4,CALU,SAR1B,ITM2A,VAMP3,CEP85,SLC39A7,TLR1,TMEM59,FAM20C,SLC2A1,STMN2,PRKCE,COPE,EI24,LARGE1,STX16,BICD2,CBLN3,AZIN2,CHID1,KCNIP3,MPIG6B,FGF23,SVIP,DLG1,ATP1A3,MYO6,GKAP1,ZDHHC17,ST6GAL1,B3GALNT1,UGCG,CLBA1,TRAPPC1,FIG4,SNAP25,WDR11,TRAPPC4,RAB1A,CHST7,TMEM50B,VAC14,MYO1B,YIPF5,DAG1,VIPAS39,ZDHHC8,SPRY1,CD14,ARF4,LMAN1,AP3S2,KDELR2,TLR8,PSENEN,MGAT4B,AKR7A2,GALNT17,CSGALNACT2,TAF11,CREB3L4,HDAC5,ADCY3,TMED9,ALB,TMED1,NBN,SLC11A2,YIF1A,BET1,GCC1,LITAF,TSNAX,FKRP,SLC35C1,CAV3,TMED3,GALNT4,TRAPPC10,MAP2K1,AFTPH,ACO1,CSGALNACT1,SNAP29,BPNT2,ATP2C1,CAV1,ZNF622,GNAQ,RAB39B,NAPG,CDC42,ST6GALNAC3,INPP5K,UBXN2B,FIBIN,TMBIM1,PDE2A,OLFM3,ATP6V0B,SYBU,ST3GAL1,RAB30,LYSET,BECN1,TRIM68,ATL1,TMED5,MSH6,HUWE1,EMP2,UNC45A,IL15RA,STK16,TMEM59L,RAB2A,TRAPPC13,STX6,IL15,ARHGAP21,TEX261,ZDHHC14,DPY30,RHEB,TLR6,BCL9,EMC8,RAF1 |
| 6.427e-07 | -14.26 | MCUB (mitochondrial calcium uniporter dominant negative subunit beta) | protein interactions | 55013 | 168 | 77 | 19454 | 5460 |
ATP5PF,CLPB,MRPS18B,HINT2,MRPS33,ZBTB16,PDE12,ETFA,KGD4,MRPS17,MRPS18C,ATP5PB,MRPL47,ETFB,NDUFA2,FAF2,PPIF,BCS1L,NEFL,PDHA1,NDUFS3,NDUFS6,NDUFA12,MRPL49,MRPS9,PHB1,COX4I1,MRPL50,PNPLA8,DBT,NDUFS8,ATP5PD,MRPS23,MRPL24,GRSF1,MRPS35,COX5A,STOML2,NDUFV2,MRPL9,MRPL18,MRPS26,HADHA,DLAT,PDHB,NME4,NDUFS2,PHB2,MRPL41,GRPEL1,MRPS7,MRPL20,SEC62,NDUFAB1,CNP,MRPL12,NDUFAF3,MRPS34,NDUFA5,MRPL53,TACO1,DLST,MRPS28,ACAT1,IL2RA,MRPL13,PTPMT1,ATP5F1B,APLNR,NDUFAF4,GNAI2,NDUFAF2,NDUFB10,PYCR2,PYCR1,MRPS16,MRPS25 |
| 6.427e-07 | -14.26 | DSTN (destrin, actin depolymerizing factor) | protein interactions | 11034 | 168 | 77 | 19454 | 5460 |
SPR,PPP1CB,TOM1L2,CFTR,ADSS2,IDH2,HEXIM1,STAT6,PIH1D1,BAP1,SOD1,HSPA8,TTC1,RNF113A,AKAP1,SRSF2,COIL,MYC,LDHB,GSTK1,GFUS,CUL3,CFL1,SAMHD1,BTF3,CFL2,ST13,LAMTOR1,POMP,HTRA2,UBE2H,SMU1,GLTP,SGTA,LDHA,DAPK1,ACTB,LGALS3,TAX1BP1,MYG1,SH3BGRL,DNPH1,ESR2,VIRMA,UBA3,NMI,B3GNT2,ETFB,ISG15,URM1,STMN2,PIR,EZH2,UBE2B,SOD2,OTULIN,AKT2,TESK2,UBE3A,G3BP1,TRIM37,HSPE1,FKBP2,CRIP1,HSPB8,LYPLAL1,DDRGK1,NME2,AGR2,PEX3,TST,SMAD9,EED,MIF,EGLN3,CDK9,ATP5PD |
| 6.497e-07 | -14.25 | RNA splicing | biological process | GO:0008380 | 382 | 157 | 18204 | 5365 |
SYNCRIP,PQBP1,DDX46,CTNNBL1,BUD31,TIA1,RBM22,SNRNP40,ALYREF,TRA2A,ESS2,PPWD1,ZCRB1,RNF113A,CDC40,RBFOX3,ECD,ARB2A,METTL14,SNRPA,LSM10,DHX16,SNRPG,RBM15B,TFIP11,FAM98A,SNRNP70,WBP11,RBFOX2,UBL5,SNRNP48,IVNS1ABP,LGALS3,LSM6,KHDC4,SRSF10,CELF6,SRSF4,MPHOSPH10,ZNF326,PPIL3,SNIP1,HSPA8,GEMIN7,SRSF1,SAP18,NRDE2,NOVA1,SRSF12,RBM41,HNRNPA2B1,NONO,SNRPB,SF3B6,TSEN54,USP39,HNRNPK,SMN1,SF3B4,LUC7L3,RBMX2,TSSC4,THOC2,DDX42,SNRPB2,HNRNPA1,DDX1,ZRANB2,DDX23,THRAP3,THOC6,SREK1IP1,SLU7,VIRMA,DDX5,NCBP2,LSM5,SCNM1,MAGOHB,DDX39B,DHX38,THOC1,RTRAF,ARMC7,ZMAT5,PPIG,RBM38,SNRPD1,PRPF31,SART3,CWF19L1,LSM8,SF3B5,RBM23,CWC15,CASC3,TXNL4A,PPIH,CDK12,AKAP8L,MFAP1,COIL,RBM42,CDC5L,HNRNPF,RBM5,SNRPD2,DHX15,PRPF19,DDX39A,TSEN34,FRA10AC1,LSM3,GCFC2,SNRPA1,CD2BP2,PABPC1,RSRC1,IK,SMU1,HNRNPC,SNRPE,PRPF18,TRA2B,AKAP17A,WDR83,DHX9,ELAVL4,DBR1,CLP1,SRSF7,CCAR2,PRPF4,LSM4,HNRNPH3,SNRNP27,PRMT5,THOC3,RTCB,SF3A1,RP9,SRSF2,WDR77,SRSF8,SF3B1,RBM17,SRPK2,GEMIN8,WTAP,SNRPD3,MAGOH,SMNDC1,LSM2,ZMAT2,SNRPN,SUGP1,EIF4A3 |
| 6.529e-07 | -14.24 | regulation of establishment of protein localization | biological process | GO:0070201 | 530 | 208 | 18204 | 5365 |
IL12B,WWP2,UBAC2,RAB23,KCNB1,CCL5,ACVR1C,ACSL4,CDC42,PPIA,PTP4A3,MIEF1,GNAO1,ERP29,IL6,EFCAB7,ARFIP1,SFRP1,RSAD2,CSK,INPP5K,UHMK1,IL12A,CDK1,DMAP1,AKT2,PDCD5,CDK5R1,OPRM1,PARD6A,SNAP25,VEGFC,HAX1,PRNP,HSP90AA1,SAR1B,MAVS,ACHE,IFI27,EFNA5,BAP1,FKBP1B,CD36,MIR148A,SNX3,PLCB1,PCK2,RBM22,HTRA2,PKIG,HDAC3,GNAZ,ATP2C1,PSEN1,MIR146A,HADH,CD81,SYT4,SFN,IL1A,CHP1,TGFB2,OSBP,SIRT7,SVIP,IGF1,DKC1,EP300,PDCD10,ENY2,UCP2,JAGN1,SLC1A1,TCAF2,TXN,RAB29,HYAL2,TGFB3,IL1B,DPH3,PPP3CA,UBE2G2,ADTRP,CCT7,DRD3,PFKFB2,NR1H2,OS9,CCT2,OR51E2,CHRM1,EDEM1,JAK2,TSG101,SUMO1,BAD,LCP1,PARL,PRKCB,PRKCE,CHGA,GSK3A,BAG3,ANP32B,NDFIP1,GHRL,SNX12,CARTPT,CNR1,FIS1,ATP5IF1,TMEM30A,IFNG,TIAM1,MDM2,PGRMC1,DYNLL1,OAZ1,IL13,UBE2D3,HPCA,OAZ3,NEO1,PTPN1,SRC,WRAP53,PPID,ANGPT1,UQCC2,HSPA8,KCNJ11,RAC2,CD200,TM9SF4,TLR4,LEP,LRRC8A,TOMM70,HUWE1,PTPN11,CHCHD4,UBL5,BNIP3L,LYPLA1,JUP,CPLX1,SUFU,RAN,PIK3R1,PIK3R2,STOM,CAMK1,TCP1,SLC16A1,SCFD1,PPARG,CCT5,TOMM7,XPO1,SMAD3,NDUFAF2,ADIPOQ,TNF,APBB3,SLC7A11,ERLEC1,SELENOK,CCN3,UBE2L3,RHBDD3,RHOU,VPS28,CTDSPL2,DERL2,STX1A,CDK5,GOLPH3L,CCT8,PKIA,HRAS,FBXW7,OAZ2,PRR5L,HDAC6,SYBU,SH3GLB1,DNAJC1,VAMP2,HCLS1,P3H1,SRI,GNA11,CHRM3,TLR2,NLGN2,SLC12A2,CD38,CFTR,CD2AP,LMAN1,CTSD,UFM1,C2CD2L,TMEM97,ARF6,PICK1,EDEM2,F2 |
| 6.579e-07 | -14.23 | ANP32B (acidic nuclear phosphoprotein 32 family member B) | protein interactions | 10541 | 149 | 70 | 19454 | 5460 |
MEPCE,AHCYL1,SAR1B,RIGI,HUWE1,TRIM26,H3C1,HSPE1,EWSR1,DMAP1,H2BC1,ACTR2,SOX2,TULP3,ANP32A,MIF,SUMO2,H2AZ1,FAM3A,RCHY1,KPNA1,BCL10,SHC1,AGR2,DNTTIP1,CD81,XPO1,CSNK2A1,PPIB,CALR,PDIA3,PGAM1,GRPEL1,MLH3,EMC1,FBXW7,TLR2,PGK1,ATP5IF1,PSMA3,ARPC2,YAF2,PMAIP1,BAP1,PEBP1,DDX39B,SOD1,RPA3,PIH1D1,DNAJC27,SDCBP,RPA2,H2AC1,PRDX3,POLR1D,PTEN,CCNF,VPS72,STK11,BAX,CDC73,SMAD2,ICAM1,UBE2H,DNAJC19,ATP1B3,KPNA6,MYC,CDC16,DHPS |
| 6.584e-07 | -14.23 | SLC7A1 (solute carrier family 7 member 1) | protein interactions | 6541 | 193 | 86 | 19454 | 5460 |
PIGW,GHITM,LMNA,RPA2,CDC42,PDCD1LG2,SYNGR2,MAVS,VIPR1,SLC39A9,RPA3,SPOP,RAB2A,ACP2,VIRMA,RHOJ,MGST3,SYNGR1,ELOVL4,CCNF,CDIPT,MGARP,ALG11,YIPF4,TP53,MTCH2,FKRP,TGFBR2,FITM2,TMEM11,SLC2A1,ORMDL3,TMBIM6,LAMP3,TMEM19,ARF6,RAC2,SEC23A,GNPAT,COMT,HRAS,SMCO4,TIMM29,SEC62,SLC19A2,CERS6,STX7,PMAIP1,TSPAN15,CD40,RHOB,FCER1G,LAMTOR1,BAG3,SCN3B,PARL,GPR89A,RMDN3,LMBR1L,STX12,RAB4A,RPN1,STIM1,CA14,CYB5R1,TOP3B,HS2ST1,SACM1L,LEPROTL1,KRAS,TMEM268,TMT1A,RHOG,FAM241B,NCR3LG1,FATE1,EMC6,RAB5C,LAMP2,TMEM237,DIRAS3,TSPO2,RHOH,HNRNPL,TMEM14A,RAB35 |
| 6.654e-07 | -14.22 | TMX1 (thioredoxin related transmembrane protein 1) | protein interactions | 81542 | 224 | 97 | 19454 | 5460 |
TMEM179B,SLC35C1,LMNB1,FAS,RAB11A,SEC61B,VDAC2,LMBR1L,MMP14,DUSP22,OTULINL,EHD1,SEC62,PXMP2,STX7,ADRB2,HSCB,PMAIP1,RAB5A,TMEM106B,DNAJC3,CBL,TLR10,RHOG,PMP22,RAB5C,MARCHF5,LAMP2,RPL7,CYB5A,CYB5B,CCR1,EZH2,STIM1,RPN1,DNAJC25,DCAKD,VDAC1,G3BP1,KRAS,EWSR1,TMT1A,UBE2H,CALU,TYROBP,NRP1,SEC63,LYPD6,COPE,TXN,ODR4,CSNK2B,CCNF,HEXIM1,EPHX1,SSR1,RPA2,LMNA,ST7,CDK7,CDC42,HSPA5,RAB9A,DERL1,SQSTM1,SYVN1,GRAMD2B,RPA3,ESYT1,LAMP3,ADIPOR2,DPP4,TLR1,CYSTM1,LMAN1,TMPO,SNN,DNAJC1,ANKRD46,FZR1,RNF128,HSD17B11,COMT,PTPN1,CD274,SRPRA,TSPAN3,DDX42,IZUMO1,CLEC2B,H2AX,FKBP8,RDH11,RAB3B,DNAJC30,IGF1R,BACE1 |
| 6.657e-07 | -14.22 | ACACA (acetyl-CoA carboxylase alpha) | protein interactions | 31 | 460 | 177 | 19454 | 5460 |
XPO1,AGR2,PIGC,CBL,SRSF1,CCDC71,EED,DIPK2A,CDK17,HNRNPL,MACROD1,ARFGEF1,PGAP2,DHX38,TOP3B,MOB3C,RPL18,VDAC1,PSMA1,KRAS,RAB18,TBCE,CYB561D2,MYC,PCCB,PSMD1,TRIB1,COP1,VDAC2,PHF21A,PRMT5,PSMD6,SNRNP40,FBXO22,MATR3,NCKAP1,ESR2,RPL27A,SSBP2,CSNK1A1,PIH1D1,SNRPA,DDX5,EP300,HSPA8,SERPINB6,STAU1,UFL1,COX5A,CSNK2A1,SHC1,UBE2N,UBE2G2,CD274,MRPS9,ARL4D,CDK6,KLF9,PRELID1,CENPM,TP53,KBTBD4,H2AX,RBM34,PSMC3,PSMA5,PSMB2,BFAR,TRIM23,ATP1B3,UBE2H,MID1IP1,PSMC5,ADRM1,CHMP5,MRPS21,DAPK3,CFTR,CDC42,H2BC11,RPA2,CSNK1G3,HECTD1,ACACA,PML,DDX46,BAP1,RNF113A,ELOF1,KDM1A,HDAC3,MARS1,PRDX1,SLC25A28,RHOG,FBXO32,ARHGAP25,NOP58,STK3,EGLN3,CSNK1E,PPP2R1A,PRKAG1,AP2S1,SART3,OTULIN,HNRNPA2B1,NDUFA4,HSPD1,UBE3A,KCTD17,RBBP7,ARL5B,SAR1B,MCM6,CUL3,RIOK2,DCAF4,BRCA1,ELMO2,RIT1,ILK,AP2M1,REEP4,RPL35,RBBP4,TOR1AIP2,PGRMC1,PRKAB1,DET1,PSMB7,UPF3B,PSMA3,RLIM,SDHAF4,NUP50,PSMC1,MOV10,FNDC11,EPOP,ARL10,HACD3,EFNA3,H2AZ1,AIFM1,CDK9,MDM2,MAP1LC3B,SOD2,PC,RIGI,VTA1,ARF4,GMPS,ATP5F1A,CDC73,ENO1,OPTN,CCNF,UBASH3B,PTEN,GANAB,GSK3A,NDN,VIRMA,PSMC4,ATG16L1,METTL14,DCTN4,OXSR1,SIRT7,DVL2,INPPL1,RPA3,PIK3R2,SMC4,MBD3 |
| 6.668e-07 | -14.22 | response to oxidative stress | biological process | GO:0006979 | 365 | 151 | 18204 | 5365 |
IL1A,ROMO1,ADIPOQ,PDCD10,UCP2,SLC7A11,MT3,LIAS,NUDT2,SLC23A2,RPS3,IL18BP,SELENOK,GPX1,TNFAIP3,TRIM32,GJB2,SLC1A1,BAK1,TXN,PCNA,HYAL2,GSTP1,RLIG1,AKT1,AIFM1,PYCR2,PEX13,GLRX2,TOP2B,GCLC,GPX6,TMIGD1,MBL2,OSER1,RHOB,SELENOS,PRDX6,TBC1D24,PRR5L,STAT6,HDAC6,STAT1,FOS,JAK2,CRYGD,CHCHD2,IDH1,OGG1,SLC25A24,EIF2S1,GPX3,MAP1LC3A,CCS,G6PD,MTF1,ERO1A,CYP1B1,CD2AP,CD38,GPX4,SOD1,BANF1,PPIF,BECN1,HBB,AIF1,MIRLET7B,STK26,PSMB5,ERCC3,NDUFS2,MMP14,TP53,UBE3A,MDM2,GPR37,PPIA,DAPK1,MMP9,MIR107,SOD2,MIR34A,PRDX3,CRYAB,CYGB,TP53INP1,HBA1,PRKRA,IL6,STAU1,MSRB3,MPV17,SRC,SOD3,CDK1,HSPA8,GPX7,NDUFS8,PRDX1,PPP2CB,JUN,PRDX2,PCGF2,COMT,HMOX2,ATF4,CYB5B,GPR37L1,SELENOP,NDUFA12,KLF4,OXSR1,MICB,PRNP,GPX2,CHCHD4,TXNIP,EDNRA,NR4A2,THG1L,PRDX4,NFE2L2,SIN3A,NDUFB4,TLDC2,EZH2,SRXN1,FKBP1B,UCN,PYCR1,HP,CD36,TACR1,SESN2,IPCEF1,NQO1,HTRA2,RWDD1,VKORC1L1,STK24,TXNRD2,ARL6IP5,PSEN1,NUDT1,HM13,FXN,SP1,GPX5,SELENON,CAPN2 |
| 6.691e-07 | -14.22 | regulation of trans-synaptic signaling | biological process | GO:0099177 | 495 | 196 | 18204 | 5365 |
FABP5,MECP2,NCDN,S100B,SLC6A4,CHRNA7,PRRT1,CHRNB2,SLC38A1,SLC38A2,NCSTN,CPLX1,CAMKV,SNCG,SLC6A6,NR2E1,PDE9A,SV2B,NTRK2,CLSTN3,ARF1,NLGN1,NTF4,PLCL1,PAFAH1B1,PPFIA3,STAU1,LARGE1,DAG1,ADORA3,ADRA1A,ADORA1,P2RY1,GABBR1,MTMR2,ATF4,SLC4A10,DLG4,SQSTM1,NETO1,HOMER1,BACE1,JPH4,SYBU,VAMP2,ATAD1,CCL2,SYP,DISC1,LGI1,IGSF11,ADNP,NPY5R,CACNB4,DRD1,GUCY1B1,NLGN2,RAB5A,FXR2,SLC12A2,CD2AP,CD38,NEFL,DMPK,CDH11,GRM2,INA,PICK1,CCR2,CX3CL1,KCNJ10,GRM8,ADIPOQ,TNF,SLC7A11,LRRTM2,SNX14,TMEM108,CX3CR1,RAP1A,EIF4A3,ASIC1,STX1A,CDK5,NTNG2,YTHDF1,MME,AGER,PLG,HRAS,CHRDL1,TBC1D24,NOG,HDAC6,SIPA1L1,USP8,ACHE,TYROBP,MEF2C,SYN3,SNAPIN,UCN,VPS18,CHMP2B,NGDN,TACR1,MIR421,MIR342,NPTN,PLCB1,OPHN1,RTN4,MIR30B,PTN,CACNG3,PSEN1,EGR2,CBLN2,GRIA2,MIR324,SYT4,ANAPC2,EPHA4,AKAP12,RIMS3,PREPL,UBE3A,LRRC4,HCRT,CASK,KCNB1,LRRTM1,YWHAG,BGLAP,PCDH17,CDC20,MIR142,DLGAP4,EIF4E,ABHD6,CPLX3,CA2,HTR2A,GRIK1,YWHAH,FLOT1,SNAP25,SLC1A3,GRM1,PRNP,NEUROD2,USP46,CHRM1,JAK2,PTEN,STXBP1,EIF4EBP2,SLC4A8,GRID1,RAP1B,SYNGR1,PRKCB,CPLX2,PRKCE,MIR545,TNR,KIT,GNAI2,GHRL,MIR320A,GRIA1,ATP1A2,CNR1,RAB3A,PAIP2,CBLN1,NSG1,PPFIA2,KRAS,RIMS4,FRRS1L,OXTR,RETN,SLC1A1,MAP1B,MIR95,DKK1,IL1B,P2RY4,SLC6A1,FAM107A,WNT7A,PPP3CA,RNF167,ADRB2,DRD3 |
| 6.815e-07 | -14.20 | MYL12A (myosin light chain 12A) | protein interactions | 10627 | 182 | 82 | 19454 | 5460 |
VDAC2,UQCRC2,GSK3A,PTEN,ATP5F1B,MRPS21,ADRM1,ACTB,ESR2,VIRMA,DYRK1A,MYC,CUL3,TOMM40,FAS,BRCA1,SP1,CDC73,UBE2H,BAP1,PML,FOS,HADHA,NDUFS2,EIF1B,PDHB,FBXW7,PHB2,SMC4,PIAS1,HSPA5,WDR77,TOMM22,UQCRC1,CFTR,CDK7,PSMB7,HSP90B1,HEXIM1,MYL6,SLC25A3,CYC1,PIH1D1,SYNCRIP,COX4I1,PHB1,NDUFB4,PPP2CB,IGBP1,ATP6V1A,CD4,KCTD15,HYPK,NDUFS8,SRSF10,CDK9,CALR,HNRNPA1,SNRNP70,CBL,HSPB1,HSD17B10,TRIM26,TNF,VDAC1,TRIM37,MEPCE,VTA1,MDC1,AHCYL1,RAF1,FBP1,KBTBD4,DDX39A,ISG15,EZH2,TFCP2,NDUFS3,PDHA1,CAPZA2,NUPR1,RPL18 |
| 6.834e-07 | -14.20 | PLD2 (phospholipase D2) | protein interactions | 5338 | 133 | 64 | 19454 | 5460 |
CSK,CUL3,OPRM1,BAG3,PCCB,PEA15,HERC4,ARF1,CCNF,STUB1,CIB2,LURAP1,TMEM74,EIF4A2,TUBB,ACTB,PPP5C,SRC,ASRGL1,PIP5K1A,STXBP1,PRKCA,CAV2,PIH1D1,CXCR4,TEX264,HSPA8,HNRNPH2,THBS3,MTDH,TTC1,MCMBP,CRYL1,FTL,ISYNA1,ANKMY2,ZCCHC10,XPO1,ATG7,INSYN1,GAPDH,CDK5RAP3,ASIC2,POU5F1,DNAJC7,VCPIP1,HACD3,SRPRA,TTC9C,TOMM70,RAMP3,CAV1,SPC24,CHRM3,CDH8,TUBB4B,AQP3,NUPR1,PLD3,TSPAN3,DNAJB4,RPAP3,BAG2,PTGES3 |
| 6.834e-07 | -14.20 | TMED2 (transmembrane p24 trafficking protein 2) | protein interactions | 10959 | 133 | 64 | 19454 | 5460 |
SMPD2,CALU,ATP1A1,SCFD1,RPS26,TM9SF4,TMED4,TMED5,RAB2A,NDUFB10,GORASP2,B4GAT1,ESR2,VIRMA,CYB5R3,CCNF,ARF1,SEC61B,GRM2,RPA2,SEC22B,PGRMC1,RABL3,PTAR1,YIPF5,TMED3,EMC1,HSCB,HSPA5,TMEM106B,PMAIP1,RAB5A,HSPA8,AGR2,CDK5RAP3,DDRGK1,RPS10,RAB1B,TMED9,UQCRH,LMAN1,SDHB,GLT8D1,SURF4,CTXN1,CCDC47,UBL4A,ARFGAP1,FAF2,DNAJC25,SRPRB,DNAJC30,KRAS,SAR1B,GALNT2,RAB18,TOMM6,TMED7,TMED1,FGF3,AKT2,RAB1A,EMC2,MAN1A2 |
| 6.845e-07 | -14.19 | PREB (prolactin regulatory element binding) | protein interactions | 10113 | 160 | 74 | 19454 | 5460 |
RAC2,HSD17B11,CORO1C,RAB35,PTPN1,NUP35,RAMP3,EGLN3,TMPO,LMAN1,DNAJC1,MARCHF4,DDRGK1,FAM20C,SLC25A46,RAB5C,DPP4,ESYT1,RHOG,GNG5,LPAR2,TMT1A,AKT2,CYP2C9,FKBP8,SLC6A8,SRPRB,RAB3B,KRAS,MSX2,SMAD1,CYB5R1,DNAJC25,CCDC47,SLC25A20,RAB4A,RPN1,TFRC,STIM1,SEC61B,RMDN3,CDC7,CYB5R3,LMBR1L,S1PR4,VDAC2,CCNF,SEC63,ESR2,CIAO1,AKT1,RIT1,HSP90AA1,LMNB1,HADHA,RAB9A,MIA2,DERL1,EP300,SYVN1,TEX264,RPA3,STX7,PXMP2,HSCB,NF2,ST7,CDC42,SEC62,OTULINL,TMEM231,SCLT1,SSR1,RPA2 |
| 6.875e-07 | -14.19 | CEP250 (centrosomal protein 250) | protein interactions | 11190 | 270 | 113 | 19454 | 5460 |
KXD1,MOV10,RPL10A,SSX2IP,RPS2,RPL24,TUBG1,ALYREF,MRPS9,RPL12,MRPS23,RPS16,RPL15,EEF1A1,ESS2,ADAMTS1,DHX9,MRPS18B,RPL3,RPL23A,RPS13,ZNF365,NOC4L,AKAP12,HUWE1,RPS17,RPL7A,TRIM32,ANKIB1,CALU,MAPRE1,IGF2BP1,RPS12,ENO1,TUBA1B,RPS3,UBB,RPL13A,DAPK1,NEK2,RPS14,ATG16L1,RPLP0,HBB,MRPS34,SQSTM1,PRPF4,ZKSCAN1,RPL27,HSPA5,MBD3,PIAS1,RPL4,SGF29,F7,YWHAG,PPFIBP1,RPL6,NDC80,MRPS35,PRPF19,RPL23,HAX1,HBA1,HP1BP3,RPLP2,MAGED2,RPL8,DHX15,HSP90AB1,RPL7,SNRPD3,RHOH,RPS10,CRTC2,TUBA1A,RPS23,RPL18,RPS11,TUBB4B,SRSF7,PABPC1,RPL31,RPS4X,GTF3C3,RUVBL1,TRIM37,HNRNPF,HNRNPC,PRSS1,HSP90AA1,H1-10,RPS9,REP15,EIF4EBP3,RPL19,RPL10,RBBP4,TUBB,RPL35,ACTB,MATR3,ATP5F1B,BORCS6,NDE1,NUP62,DDX5,ATP5IF1,HSPA8,HDAC5,FTL,LZTFL1,GRPR |
| 6.900e-07 | -14.19 | H2BC3 (H2B clustered histone 3) | protein interactions | 3018 | 364 | 145 | 19454 | 5460 |
H2AC1,APOBEC3C,TIMM13,ACTL6A,SKP1,HNRNPA0,SRSF2,EP300,CCDC86,XRCC5,ICAM1,BRCA1,CHTOP,YWHAZ,PSMD14,MCM4,CPSF2,BTF3,RFC5,RNF40,PRPF31,CUL3,HNRNPAB,SFN,HNRNPC,CREBBP,ERH,USP38,DYNLL1,RBBP4,PSMD4,USP16,ZMYM2,PARP2,IRF2,SMARCB1,MTA2,CHMP4C,TUBB4B,NUP153,RFC3,SSRP1,RAD21,RFC2,UBE2A,MCM6,RUVBL1,RTCB,RUVBL2,PCNA,AKT2,YWHAB,HNRNPD,DDX1,CBL,H2BC17,YWHAG,DPY30,RPL6,CETN2,HMG20A,SPTAN1,DYNC1I2,SNRPD3,NOP58,KRT8,WDR82,MAGED2,SRSF1,SIN3A,HEXIM1,H2AC7,CDK1,RPA2,LMNA,RPRD1B,H2BC11,GTF3C4,PIP5K1A,SNRPN,SPTBN1,PIAS1,GTF2I,H2BC12,PRKCB,NBN,PPM1G,RPA3,BAP1,IGF2BP1,ATP1A1,RC3H2,RACGAP1,PPP1CC,PRKACB,AKT1,SMARCA5,VIRMA,DYRK1A,CDC20,SCML2,COPE,MACROH2A1,LIG3,EIF4A3,RNF8,RAD23B,SRP72,CHAMP1,DMAP1,TFCP2,ZMYM3,UBR7,H2AX,TP53,KBTBD4,MDC1,MEPCE,RNF20,H3C1,ANAPC11,DHX9,RING1,SEPTIN7,MAP1B,BRD3,KPNA1,H2AC4,EXOC2,TUBG1,EID1,ZMYND11,HDAC6,CD81,USP2,USP3,GRSF1,CDC5L,DKC1,POLE3,MIF,FZR1,SSBP1,H2AZ1,SYNCRIP |
| 6.913e-07 | -14.18 | DHCR7 (7-dehydrocholesterol reductase) | protein interactions | 1717 | 171 | 78 | 19454 | 5460 |
LMAN1,RHOH,ARF6,ARL4D,RAC2,HSD17B11,ARL10,RAB35,CD274,PTPN1,RB1CC1,PEX3,AGR2,RHOG,DDRGK1,ACP6,LAMP3,FAM20C,RAB5C,PTPN5,LAMP2,RNASEL,RAB3B,VDAC1,KRAS,TMT1A,CYP2C9,RHOBTB1,RND3,RAB4A,RPN1,EZH2,DNAJC25,ACTR1A,CCDC47,RAF1,ESR2,VIRMA,RHOJ,NDN,SEC61B,CYB5R3,LMBR1L,UBE2H,RHOB,DCAF4,LMNB1,LAMTOR1,TOMM40,BTF3,RAB11A,CUL3,RAB2A,STX7,COIL,PXMP2,SLC25A51,STAU1,RAB9A,EP300,RNF113A,PRKCB,SYVN1,EXD2,IDH3A,RHOU,BMPR1A,RPA3,SSR1,RPA2,CFTR,SEC62,CDC42,RND2,OTULINL,PGRMC1,BET1,CCND1 |
| 6.970e-07 | -14.18 | AKIRIN2 (akirin 2) | protein interactions | 55122 | 74 | 41 | 19454 | 5460 |
RIGI,PSMD12,PSMC1,MYOZ3,DHX16,HNRNPF,PSMA2,PSMA1,PSMA5,PSMA3,PSME1,RNF181,CSNK1A1,PSMC3,PPID,PSMB7,SPG21,PSMB9,PSMB3,PSMC4,ZBTB2,PSMB6,PSMD6,BUD31,PSMD4,PSMB1,PSMC5,PSMB4,PSMA6,ACTA2,PSMB5,RAN,PSMD7,CCDC85B,NTAQ1,PSMD1,FBXO7,SEC13,PSMA4,PSMB2,PSMD3 |
| 6.970e-07 | -14.18 | BNIP3L (BCL2 interacting protein 3 like) | protein interactions | 665 | 74 | 41 | 19454 | 5460 |
CYB5B,CASK,LMNA,SMCO4,MAP1LC3B,GABARAPL1,GABARAPL2,DOK5,TP53,MTX2,MTCH2,FBXL4,GABARAP,BNIP3L,ADIPOQ,EWSR1,AKAP1,PMAIP1,SQSTM1,KLHL23,RINT1,CLEC7A,ATP5MK,CBL,BAX,BCL2L1,HTRA2,IKBKB,TMEM11,PPTC7,RHEB,BAG3,FATE1,CREBBP,BAK1,SLC25A46,DUSP3,MAP1LC3A,CLN8,BOK,BAD |
| 7.000e-07 | -14.17 | regulation of intracellular transport | biological process | GO:0032386 | 264 | 115 | 18204 | 5365 |
NF2,NUS1,SNAPIN,CD36,CHCHD4,SAR1B,MAVS,MECP2,RNF139,IFI27,PSEN1,CAMK1,CD81,SCFD1,BORCS5,SFN,JUP,SNX3,SUFU,MRLN,RBM22,RAN,PKIG,PIK3R1,MLC1,HDAC3,PIK3R2,CDC42,NCBP2,CRYAB,OAZ1,EHD1,OAZ3,EFCAB7,ARFIP1,IER3,THOC2,MIR185,TMEM30A,UBAC2,IFNG,MX2,RAB23,MDM2,STX18,TM9SF4,LEP,BVES,HSP90AA1,PTPN11,PTPN1,UHMK1,CALY,SRC,CDK1,ANGPT1,DMAP1,ARHGAP1,PPP1R12A,PDCD5,MTMR2,NRDE2,SUMO1,LCP1,PPP1CC,MAP2K1,PCSK9,OS9,CHRM1,VAMP2,EDEM1,JAK2,HCLS1,UFM1,FEZ1,MSN,NUP153,YIPF5,TMEM97,AKAP8L,EDEM2,BAG3,ANP32B,RIOK2,SNX12,PLN,MIR17,ERLEC1,RAB11A,MAP1B,TXN,RAB29,HYAL2,XPO1,CHP1,SMAD3,SIRT7,SVIP,EP300,PDCD10,ADIPOQ,STK11,PKIA,REEP6,OAZ2,PRR5L,TRIM46,RAB11B,CTDSPL2,DERL2,DHX9,CDK5,IL1B,RINT1,UBE2G2 |
| 7.036e-07 | -14.17 | SUGT1 (SGT1 homolog, MIS12 kinetochore complex assembly cochaperone) | protein interactions | 10910 | 273 | 114 | 19454 | 5460 |
ACTR2,EEF1A1,DDX39A,ACTR1A,MTCH2,CNOT6L,STRADB,PTGES3,SEPHS1,FKBP8,DYNC1I1,CAMKV,IDH1,FAF1,LRRC8B,DNAJC7,STYK1,PTGER4,COPS5,CSNK2A1,LRRC40,LMAN1,CDC5L,PSMB1,AIP,AIFM1,MGME1,PARD6A,UBE2M,TRIM36,SHOC2,RPA2,HSP90B1,CFTR,TPT1,CRYZ,MIS12,LCP1,RPA3,PNPO,UBE2H,CHORDC1,BICD2,CFL1,AKT1,MYG1,IDE,CEP97,BUB3,NDN,DAPK1,OPTN,TSSK1B,CCNF,NLRP2,GLE1,PIR,HDAC11,TUBA1A,PPIL3,TXNRD1,AHCYL1,PSMA1,TRIM37,RUVBL2,RPAP3,TESK2,UBE3A,S100B,LSM14A,LRRC57,WDR12,FKBP4,CNOT2,PSMD3,CACYBP,HSP90AB1,CHMP2A,HNRNPL,TTC9C,ADCK1,PSME2,HEXB,PAK2,DET1,FBXL4,RNF41,SKP1,HSPA8,AKAP1,HSP90AA1,HTRA2,NLRP3,DNAJB6,ILK,LAMTOR1,MRPS25,LRRC20,SAMHD1,BTF3,BAG3,MYC,DSN1,RAB11A,HNRNPAB,PPP5C,CLIC4,TUBB,LRRC1,LRRC28,ANAPC2,FBXL14,S100A6,CNOT6 |
| 7.045e-07 | -14.17 | ATP2A1 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1) | protein interactions | 487 | 415 | 162 | 19454 | 5460 |
VAPB,ARMCX3,UBAC2,FDFT1,GOSR2,PGRMC1,BET1,NOTCH2,TOR1AIP2,TLCD1,UFL1,NPTN,RER1,PXMP2,ITGAV,SCFD1,PLN,ZMPSTE24,VMP1,ENTPD4,TMEM38B,VEZT,CUL3,LRRC8A,ABHD12,CHP1,ATP6AP2,CYB5R3,DLST,SLC30A7,GGT7,GPR89A,SEC61B,EZH2,VAMP2,STIM1,RPN1,PDHA1,TAPT1,CYB5B,PLD3,STBD1,MACO1,SUPT5H,FAF2,CYB5R1,TULP3,LGR4,COA1,EMC8,HS2ST1,PAK6,RETREG1,SAR1B,RINT1,SCD5,CDK5RAP3,AGR2,C2CD2L,HSPB8,XPO1,DDRGK1,SLMAP,TMEM97,UQCRH,NUP35,GJA1,STX5,CYB5A,SSR1,USE1,STOM,METTL14,SLC12A2,LEMD3,PIGW,CYC1,RABL3,ARHGAP1,SEC22B,CFTR,HACD2,CERS2,YKT6,HMGB1,LPAR1,CLDND1,TMEM209,TEX264,TMX2,ITM2B,FADS2,MTDH,SPCS2,RTN4,ARFGAP3,AP2A1,DNAJC19,GGCX,DEPDC1B,HMOX2,GORASP2,SH3BGRL,VKORC1L1,UQCRQ,SEC63,VAMP3,ATL1,PTPMT1,GPD2,TFRC,SLC25A24,SNAP29,PREB,CCDC47,FAM162A,LBR,DDX39A,UBIAD1,RAB3B,SRPRB,FKBP8,RIGI,RUSF1,NSDHL,MAP1B,RNF167,ATP2B4,STX18,YIF1A,TMX3,EMC2,MUL1,POR,SMIM12,ESYT1,OSBPL8,AGPAT1,ORC5,EI24,TMEM199,SELENOS,FAR2,DHRS7,HM13,ROGDI,RAB23,ARL6IP5,DNAJC1,ARF6,RPS27L,SLC25A17,LMAN1,TMPO,SLC38A2,PTPN1,ITGA6,SRPRA,HACD3,ST6GAL1,CAMLG,EXT1 |
| 7.071e-07 | -14.16 | ECD (ecdysoneless cell cycle regulator) | protein interactions | 11319 | 112 | 56 | 19454 | 5460 |
VTI1B,DNAJC1,EGLN3,CEP19,KIAA1143,ECD,DNAJC7,MED4,PRPF19,CSNK2A1,XPO1,TPM3,KRAS,TSSC4,HNRNPF,DNAAF10,RUVBL1,PSMB10,RIGI,PTGES3,EWSR1,RAB27A,MYO1B,DNAJC2,GPBP1L1,PSMC3,SART3,KBTBD4,TP53,RBM38,CD2BP2,NDN,SNRNP40,CCNF,GCFC2,CTNNA1,PSMC5,SNRPD2,GSK3A,RPS9,FAS,TXNIP,CUL3,ANAPC15,PSMD1,NONO,HSCB,TRIM52,NCDN,PSEN2,GRIA2,HSPA8,PIH1D1,ATG16L1,WDR83,GABRA1 |
| 7.071e-07 | -14.16 | SARS1 (seryl-tRNA synthetase 1) | protein interactions | 6301 | 112 | 56 | 19454 | 5460 |
HRAS,TSG101,XPO5,SUMO2,MARCHF4,CAV1,GTF2E1,COPS5,XPO1,ATG7,HSPB1,HAX1,KPNA1,DNAJC7,SMG9,EHD4,ASF1A,KRAS,SAR1B,PTGES3,RIGI,DUSP21,MTCH2,TP53,MSX2,CHMP4C,DNAJC2,CTTN,CCNF,LMBR1L,GTF2A1,TENT5C,FBXO22,STAT1,NOPCHAP1,PAPOLA,CUL3,SEC13,SLC25A1,MYC,RIT1,SNX5,PFDN2,OAT,PPM1G,SOD1,RPA3,BAP1,ARFIP1,TTC1,STAU1,FBXW7,EMC1,PPP1R8,ATP6V1C1,RPA2 |
| 7.071e-07 | -14.16 | UBE3A (ubiquitin protein ligase E3A) | protein interactions | 7337 | 406 | 159 | 19454 | 5460 |
PSMB2,AR,USP14,ATP1A1,PDCD4,CCNF,PSMA6,TUBA1B,ENO1,PSMC5,DAPK3,ADRM1,UBB,UBE2L3,RPL22,DEK,VIRMA,BCCIP,PSMC4,ATG16L1,SUMO1,CFTR,RSAD2,P3H1,RPA2,CDK1,CARHSP1,KRT7,ACACA,RPA3,SOD1,PML,IRF3,PGK1,DLAT,CLU,HSPA5,CALR,COPS5,ZFAND2B,EID1,CCDC92,SMAD4,ANKRD49,PSMD7,WDCP,PDE1B,SYNCRIP,HACD3,ACTA2,EEF1AKMT3,UBE2G2,UBE2N,DSTN,PSMB1,MTAP,MDM2,YTHDF2,CDK4,TP53,TMEM31,DDX42,RAD23B,PSMC3,DLG1,SNAPC3,PSMA5,SEM1,SRPRB,POLE4,OLA1,ZNF250,MYC,PSMA4,IRF1,PSMD1,UFD1,CKB,ATP1A3,PSMD14,YWHAZ,BRCA1,PRSS1,RMI1,LMBR1L,DOK4,IRF2,ENO2,PRMT5,PHKB,USP16,PSMD4,PSMD6,ACTB,TUBB,PSMB6,TNPO3,ESR2,PSMB3,ETF1,PSMB7,TCF19,DDX39B,PYM1,WBP2,HSPA8,TXNL1,PSMA3,LCN1,DR1,JADE1,UBE2D3,PSMC1,PXMP2,UNC45A,PSMD3,PDIA3,ATG9A,PRDX1,YWHAG,YWHAH,MRPL9,PHKG1,BTF3L4,CTNNB1,UBE2D1,HBA1,RNF152,PSMD10,CDKN1B,SMAD9,FBXO32,PSMB5,PSMB4,COPS7B,AFTPH,PGR,NOP58,SUMO3,RPL7,LSM5,CCAR2,CGGBP1,PPIA,HSP90AB1,MAPK10,ASPM,FAF2,KDELR1,TMEM14B,CSTPP1,UBE3A,PDIA6,PSMA1,PSMA2,MCM6,PSMD12,CA10,PAX6 |
| 7.085e-07 | -14.16 | regulation of mononuclear cell proliferation | biological process | GO:0032944 | 242 | 107 | 18204 | 5365 |
ARG2,IL2RA,TNFRSF14,IL5,BCL2L1,JAK2,TIRAP,PLA2G5,CDKN1A,TGFBR2,IL2,CCR2,EFNB1,CCL19,AIF1,SFTPD,PDCD1LG2,DLG1,CTLA4,CD38,TRAF6,NDFIP1,GPAM,FGF10,CTNNB1,SELENOK,NCK1,RPS3,TFRC,IGF1,TWSG1,VSIR,CD209,SLC39A10,IL1A,IL10,XCL1,FCGR2B,TNFSF18,PYCARD,AGER,MZB1,HMGB1,CD1D,PPP3CA,PTPN22,BCL6,CD40,IL1B,IL23A,CD28,CD80,MEF2C,IL7,CHRNB2,LGALS3,IL15,TICAM1,EPO,TYROBP,MIR181C,CD46,MIR30B,TNFRSF9,MIR21,CD81,LILRB4,TNFRSF1B,TLR9,IL20RB,MYD88,IRF1,PRKCQ,TACR1,GPNMB,LST1,IL4,IL21,IL6,CD86,IL13,SDC4,CCL5,IDO1,SOS2,MIR185,IL12B,SLC7A1,ST6GAL1,IL6ST,PRNP,BTN2A2,TNFSF8,PELI1,LEP,CD40LG,TLR4,SASH3,MIF,RAC2,IL18,PNP,CD274,IL12A,FOXP3,LILRB1,DHPS |
| 7.093e-07 | -14.16 | Hepatitis B | KEGG pathways | hsa05161 | 144 | 78 | 7161 | 2463 |
PTEN,KRAS,PIK3R1,TGFB3,SMAD3,AKT1,PIK3R2,STAT6,IFNAR1,MMP9,CCND1,CCNA2,TLR4,MAPK10,CREB3L4,CREBBP,IKBKB,FASLG,JUN,AKT2,STAT1,CDK4,CASP12,EGR2,TICAM1,STAT5A,PRKCB,CREB3,CDKN1A,TBK1,RIGI,PCNA,YWHAB,PIK3R3,TLR2,IRF7,PIK3CA,TNF,BAD,BAX,IFNA13,MAVS,TLR3,CREB1,FOS,TGFB2,CDK6,TICAM2,TP53,YWHAZ,EP300,SMAD4,SRC,HRAS,IRF3,NFKBIA,TIRAP,RB1,BIRC5,CXCL8,RAF1,ATF4,IFNA2,JAK1,ELK1,MAP2K1,STAT2,IFIH1,NFKB1,MYC,IFNA10,FAS,IFNB1,AKT3,MYD88,PRKCA,CDKN1B,IL6 |
| 7.111e-07 | -14.16 | small nuclear ribonucleoprotein complex | cellular component | GO:0030532 | 84 | 46 | 19108 | 5553 |
ARFGEF1,SNRPD3,DDX46,SNRPB,LSM3,SNRPD1,LSM5,HEXIM1,SNRPA,SNRPN,ZMAT2,LSM10,TXNL4A,SF3B1,TSSC4,MEPCE,SF3B6,LSM2,SNRPA1,PPIH,RBMX2,SNRPG,USP39,SNRPB2,PRPF4,SNRNP27,SF3A1,SART3,SF3B5,PRPF18,LSM8,SF3B4,RBM42,DDX23,SNRNP40,SLU7,SNRNP70,SNIP1,CD2BP2,DDX39B,LSM6,SNRPD2,SNRPE,LUC7L3,PRPF31,LSM4 |
| 7.175e-07 | -14.15 | STXBP6 (syntaxin binding protein 6) | protein interactions | 29091 | 21 | 17 | 19454 | 5460 |
HRAS,STX8,STX10,SNAP23,XPNPEP1,SNAP25,KRAS,NAPG,VTI1B,STX7,STX6,SNAP29,EXOC1,ATG7,NAPA,STX1A,STX12 |
| 7.223e-07 | -14.14 | TUBA1A (tubulin alpha 1a) | protein interactions | 7846 | 692 | 252 | 19454 | 5460 |
BAG2,SLC25A5,OSTM1,RAD21,CDK20,TRIM37,HOXB1,ERLIN2,FAF2,B3GALT4,OTULIN,STK16,AQP3,NGB,PPID,EZH2,SKA3,COPS2,CCAR2,AGK,ACTL6B,HSPB8,ATG7,NDC80,ICAM2,FAM174A,CAMSAP2,HAX1,RHOG,NUBP2,HADHA,TTC1,NMRAL1,COIL,CFAP119,NPTN,NUDT3,CDKN1A,ALKBH3,SLC25A3,ANXA7,ARMCX3,VAPB,MED23,FAM43A,AP2M1,CD79B,MAT2B,TUBB,RBBP4,SIAH1,PRDX2,JPT1,TOMM40,CUL3,HTRA2,PFDN6,PFDN2,HSP90AA1,KLK5,PFDN4,SP1,YWHAZ,BLVRA,SLC25A10,LTA,TFPT,SMN1,TUSC3,ARF4,TTC4,TCP11L2,DDX39A,LBR,CTDSP2,CLEC2B,CCT5,COMTD1,STARD13,GEMIN7,MLLT11,RB1,NAA30,EEF1AKMT3,AIFM1,DFFA,SRPRA,EFNA3,CDK9,MAPRE2,KCTD15,ARF6,DAG1,HDAC6,LAMP3,SSX2IP,SQSTM1,CST11,WNT7A,TTR,CNP,MX1,WDR5B,RBFOX2,GP9,CTDSP1,PTEN,PPM1M,ENO1,CHRM4,TUBA1B,CCNF,PDCD5,TECR,ABHD17A,TUFM,IL2RB,ZMYND19,MAPRE1,CDC73,STK11,TXNIP,SCPEP1,CCT8,RAB8B,PFDN1,VDAC1,RUVBL1,HNRNPF,SOX2,TUBA1A,ERRFI1,MAX,BTG1,TUBB4B,S100A8,MAGED2,SSR2,HSP90AB1,CCT7,TRMT61A,RAMP3,TCP1,CTNNB1,DDRGK1,WWP2,PFDN5,POU5F1,CBL,NCK1,THBS3,HSPA8,HDAC5,RCCD1,DDX39B,STAU1,PHB2,UFL1,TIMM17A,UBE2D3,INSYN2A,TSHR,PAFAH1B1,TOMM22,SYK,PACRG,UBAC2,PRMT5,VDAC2,CRYBB3,PSMB6,TIMM21,ATP5F1B,MLF2,BRINP3,BTF3,PSMD1,PRMT6,NXPH3,MYC,THTPA,SERPINH1,DNAJB6,ICAM1,CRMP1,PSMD14,CCT2,PELI3,SPCS3,GALNT12,LRRN4CL,RAB13,SLC16A1,POC1B,SLC25A11,TKTL1,MEPCE,PDRG1,TMEM33,TNFSF8,MGARP,TP53,UBL4A,RNF8,SERPINB11,CHAMP1,TFCP2,BRINP2,RPS27L,GAPDH,CD81,COMMD5,DNAJB2,ACOT8,USP15,CXCR1,KPNA1,AKAP8L,FAM187B,SHC1,TUBG1,PGK1,TMEM263,HSPA5,HDAC3,KLRD1,CFTR,NTPCR,GABRA1,HCST,POLR1D,ING5,TRIM36,HEXIM1,SSR1,TCP11L1,SLC1A1,B4GALT1,EIF2S2,CDC20,SMURF1,CEP41,KCTD9,MORF4L1,SLC25A1,MAT2A,AKT1,CALU,ANAPC4,RC3H2,F9,ATP1B3 |
| 7.250e-07 | -14.14 | NPLOC4 (NPL4 homolog, ubiquitin recognition factor) | protein interactions | 55666 | 185 | 83 | 19454 | 5460 |
GLUL,TMT1A,CYP2C9,FAF1,VPS26B,UBE3A,HNRNPK,TGFBR2,KRAS,NEDD8,PDE12,UFM1,FLOT1,TP53,ADORA1,KBTBD4,UBL4A,RAF1,FNTB,ISG15,FAF2,KDELR1,NDUFS3,DXO,TMEM31,EZH2,OR6M1,RAD23B,FBXO32,RPRD1A,SRP14,MRPS9,KCNA2,KCTD10,PRNP,SVIP,HNRNPL,EGLN3,EDEM1,MTMR12,SELENOS,UBXN6,MOV10,ATG9A,ZFAND2B,PPIB,UBXN10,VCPIP1,PSEN2,RPA3,SLC32A1,DR1,ADRB2,NSFL1C,NDUFS2,TMUB1,PXMP2,UBA52,ST7,CDC42,CD2AP,UBAC2,PICALM,RPRD1B,LMNA,FKBP10,EIF4A3,SURF2,NFKBIA,ENO1,CCNF,SEC61B,ETNK2,TXNDC12,SMURF1,CLRN2,LRRC73,PYCR2,USP13,UFD1,MTPN,ADK,GZMK |
| 7.250e-07 | -14.14 | CMBL (carboxymethylenebutenolidase homolog) | protein interactions | 134147 | 79 | 43 | 19454 | 5460 |
RAF1,PGM1,SAP30,H2AX,CD2BP2,RPA2,PIH1D1,FKBP1A,UBE2M,TRAPPC13,PPME1,HEXIM1,SOD2,RPA3,TRAPPC1,TRA2B,MEPCE,EMC4,CUL2,STK38L,DDRGK1,CAPG,AR,BAG3,USP14,AGR2,TRAPPC2L,CRBN,MDH1,UBE2H,NQO1,TRAPPC4,TST,SRSF1,NAP1L5,FABP5,CCNF,TRIM24,EIF4A2,ACP2,VIRMA,SMURF1,TSPYL4 |
| 7.297e-07 | -14.13 | ARHGAP23 (Rho GTPase activating protein 23) | protein interactions | 57636 | 55 | 33 | 19454 | 5460 |
PRDX3,DDX39A,ZC3H14,IPO8,SRFBP1,SAPCD1,NOL7,PNMA2,NEFL,CCDC86,DLAT,PCNA,LSM14A,SNRPA,AZGP1,MEPCE,FARSA,KPNA2,HMGB1,NT5C2,HNRNPA1,YWHAG,MYC,MAT2A,YWHAB,MECP2,HP1BP3,CTNNA1,SF3B6,SNRPB2,VIRMA,TAB1,INA |
| 7.347e-07 | -14.12 | TMEM14B (transmembrane protein 14B) | protein interactions | 81853 | 279 | 116 | 19454 | 5460 |
REEP4,TVP23B,THBD,PRRC2A,CYB5R3,TMEM229B,FCER1G,CYB561,SLC35E4,FIS1,CNIH4,SCN3B,RBM15B,ZDHHC24,TLCD1,NKAPD1,JAGN1,TMEM203,RABAC1,TMEM220,NCOA5,APOC2,MFAP1,HEXB,AGTRAP,SLC16A10,NCALD,SLC48A1,VAMP1,OTULINL,TMEM97,TMEM14A,SLC19A3,MFSD5,SCAMP5,C2CD2L,PDZK1IP1,MARCHF5,PMP22,SYNJ2BP,PSMD3,EMC6,TMEM60,HIGD1C,TOMM6,SAR1B,LEPROTL1,LSM14A,UBE3A,TMEM147,FHL3,SLC39A7,TMEM14B,STX12,DHX38,NEU1,NCSTN,SLC7A8,PLP1,APOC4,PTPMT1,SFXN2,SYNGR1,SMPD2,PPIG,VAMP5,CREB3,CSK,HMOX2,NINJ1,TMUB1,ORMDL1,TMX2,DDX46,TMEM243,TMEM254,STOM,TIMM23,LMNA,SLC35E3,TIMMDC1,SLC35F6,BLCAP,ABHD5,PLP2,TOP1,VTI1B,FUNDC2,STX6,COMT,FA2H,HSD17B11,TMEM42,TMEM11,BTN2A2,CDK12,TMEM19,EI24,TSPO,CIDEB,TMEM199,B4GALT7,FKBP8,TMEM50A,SFT2D2,TMEM50B,SFXN1,STX8,SNIP1,YIF1A,UNC50,SLC35F1,RP9,INSIG2,YIPF4,UBIAD1 |
| 7.351e-07 | -14.12 | UBLCP1 (ubiquitin like domain containing CTD phosphatase 1) | protein interactions | 134510 | 84 | 45 | 19454 | 5460 |
LUM,RPA3,HSPA8,UBE2K,UNC45A,PSMC1,CHRNA7,PAQR3,PSMC4,UBLCP1,PAAF1,RPA2,UBE2M,DOK4,PSMC5,PSMD6,ADRM1,MED17,PSMD4,PSMB2,CABCOCO1,PSMD1,MTPN,PSMD14,UBE2H,ERP29,PRPSAP1,FGF12,TOLLIP,SEM1,PSMD12,PGAP2,GTF2E2,PSMC3,AASDHPPT,HNRNPL,SPPL3,RPL35A,WIF1,ZBTB2,CHI3L1,PSMD3,PSMD7,PSMD10,SMAD4 |
| 7.446e-07 | -14.11 | SRRM1 (serine and arginine repetitive matrix 1) | protein interactions | 10250 | 320 | 130 | 19454 | 5460 |
CCT5,DUSP1,EEF1A1,CD2BP2,RBM34,CBX3,NUPR1,ILF2,SNIP1,HUWE1,RPL17,GRSF1,ZMYND11,GTF2E1,CSNK2A1,SNRNP70,H2AC4,CHCHD1,BRD3,ARL10,ALYREF,LDLR,PRR3,TOP1,CAND1,FZR1,CWC15,CDC5L,TMPO,RBM42,SF3A1,CFTR,GRM2,RPA2,LMNA,RPLP0,SIRT7,NLE1,RBM23,BAP1,MTDH,RNF113A,CLK1,FBXW7,RPL4,GTF2I,EIF5B,CIAO1,DNAJC8,USP14,PPP1CC,NONO,RC3H2,SPOP,UBE2H,NRP1,EIF4A3,CSNK2B,GSK3A,RPL13A,VIRMA,SRPK2,DEK,SMURF1,E2F4,RAF1,RPS7,RHOBTB1,SNRPE,TOP2B,SRSF7,EWSR1,DHX16,H1-6,KRAS,SSRP1,RAD21,SRSF4,RPL28,DPY30,ZCCHC10,IFI16,PRPF19,TRA2A,DDRGK1,YWHAH,YWHAG,DDX23,MAGOH,ASB7,MED4,SRSF1,EED,SNRPA1,SNRPD3,PAIP1,DHX15,ZC3H14,DET1,VPS18,MED23,NCOA5,UPF3B,NKAPD1,DDX39B,SNRPA,DDX5,HSPA8,SF3B1,STAU1,UFL1,SRSF2,TRA2B,SAP18,CUL3,MYC,SNRPB,BTF3,DCAF4,RPS5,CMTR1,CRYBB3,ZNF22,GTF2F1,SF3B4,SNRPD2,SNRPD1,SNRNP40,APEX1,SNRPB2 |
| 7.446e-07 | -14.11 | MGST1 (microsomal glutathione S-transferase 1) | protein interactions | 4257 | 120 | 59 | 19454 | 5460 |
GNB4,PHB2,STAU1,PDHB,EMC1,HADHA,VIP,ATP5MK,RPA3,CAV2,SLC25A3,VAPB,RPA2,RAB6A,PRDX3,GNB1,VIRMA,ESR2,ARMC6,SPCS1,LYZL6,ATP5F1B,BST2,SEC61B,CYB5R3,UQCRC2,DNAJB6,LAMTOR1,HMOX2,RAB11A,MORF4L1,RAB2A,RALB,HS2ST1,GALNT2,EMC2,GNG5,SFXN1,RAB1A,SLC25A24,SLC25A20,RPN1,EEF2,CYB5R1,MAP1LC3B,MTCH2,ATP5PB,CCDC47,RAF1,CDK9,RAMP3,DYNC1I2,ARL6IP5,OCIAD2,PHB1,AGR2,STOML2,ATP5MG,RAB5C |
| 7.476e-07 | -14.11 | mitochondrial transport | biological process | GO:0006839 | 180 | 84 | 18204 | 5365 |
SLC25A20,MIR17,AGK,MTX2,TIMM8A,SLC25A12,DNLZ,SLC25A32,TRMT10B,TOMM7,ATP5IF1,TST,TIMM21,NPTX1,SLC35F6,PPIF,PSEN1,SLC25A51,TIMM17A,MIR29C,SAMM50,TOMM20,TIMM23,BCL2L1,MAIP1,SLC41A3,TIMM29,MRPL18,MPC1,SFXN1,SLC25A26,CHCHD4,GSK3A,TOMM6,SLC25A24,PMAIP1,TOMM40L,SLC25A5,TIMM8B,BAD,MIR29A,BNIP3L,PPM1K,SLC25A3,SLC25A21,TOMM22,GCLC,SLC25A46,HSPD1,AIFM1,TIMM10,SLC25A23,HSP90AA1,SFXN2,TMEM14A,TOMM70,SLC25A31,SMDT1,GHITM,MTCH2,GRPEL1,SLC25A28,UCP2,BLOC1S2,GRPEL2,VDAC2,ROMO1,NAIF1,DNAJC19,MUL1,BOK,TP53,IER3,BAK1,BAX,SLC25A4,TOMM40,SLC25A1,TIMM13,CNP,CPT1B,CPT2,SLC25A39,ACAA2 |
| 7.501e-07 | -14.10 | Class I MHC mediated antigen processing & presentation | REACTOME pathways | R-HSA-983169 | 373 | 161 | 10285 | 3229 |
SEC22B,ANAPC4,CD14,SEM1,PSMB4,CDC23,TLR2,IKBKB,ITGB5,SEC61G,SEC23A,UBE2E2,PSMD4,FBXO31,ANAPC11,HSPA5,RPS27A,ITGAV,KLHL22,UBE2D3,PSMA1,PSMC3,PDIA3,FBXL4,UBE2N,SEC61A1,PSMC1,CUL3,ASB3,FBXO30,SPSB1,RNF144B,FBXO7,UBE2K,PSMA6,PSMB2,PSMD1,TAPBP,ZNRF1,RNF14,UBE2V1,SMURF1,CCNF,VAMP3,HECTD3,TLR1,KBTBD13,FBXO9,FBXL19,RCHY1,RBCK1,TRIM37,CD36,FBXL3,PSMD10,ATG7,MRC1,ASB1,UBA52,VAMP8,SEC13,UBE2S,KLHL25,TLR6,AREL1,DET1,SOCS3,TRIM21,ASB7,KLHL3,PSMB3,ANAPC13,SAR1B,UBE2H,PSMA5,RNF115,SIAH1,FBXW4,HUWE1,FBXW7,MYD88,FZR1,PSMB9,WSB1,RNF126,PSMD6,ANAPC2,TRIM36,RNF41,STUB1,UBE2D1,PSME2,FBXO44,UFL1,UBE2M,RNF182,FBXL14,RLIM,RNF7,KBTBD6,PSMD12,CALR,FCGR1A,TIRAP,HERC3,FBXO22,HERC4,KLHL9,UBE2V2,WWP1,PSMD7,TRAF7,ASB11,UBA3,SKP1,PSME1,UBE2B,CUL2,ASB8,FBXL7,UBB,TLR4,CDC26,UBE2F,SIAH2,ELOC,PSMD14,UBE2L3,HECTD1,UBE2G2,UBE2A,TRIM11,PSMC4,PSMA3,PSMB5,CDC20,TRIM32,TRIM63,PSMB1,CDC16,SNAP23,PSMD3,MYLIP,PSMB7,FBXO32,RNF34,ZBTB16,UBE3A,UBE2E3,SEC61A2,SEC61B,PSMB6,FBXW11,PSMA2,PSMB11,PSMC5,B2M,PSMB10,LY96,PSMA4,UBE2W |
| 7.532e-07 | -14.10 | H2AC21 (H2A clustered histone 21) | protein interactions | 317772 | 216 | 94 | 19454 | 5460 |
PPM1G,RPA3,FLCN,NPM3,DGCR8,HMGB1,RPL4,NUCKS1,TOMM20,UTP23,ATG16L1,TPT1,LMNA,RPA2,RNF146,RPLP0,HEXIM1,MACROH2A2,ENO1,FGFBP1,RPL13A,VIRMA,SRPK2,SMARCA5,RPL7A,H2BC9,RC3H2,ZBTB38,UBE2H,MAPRE1,RPL3,RPL23A,H3C1,MEPCE,RPS13,RPL17,SRFBP1,APOBEC3D,H2AX,RBM34,NUPR1,H2AZ1,KRR1,TOP1,FAM118B,SURF6,SUV39H1,MED27,POLB,H2AC4,RPS2,BRD3,MAP4,EP300,CFDP1,H2BW1,WDR77,H1-5,ZNF428,SDC2,ELOVL1,RPL37A,RPL35,RPL19,PARL,MYC,ZNF668,BTF3,ZCRB1,H1-10,H1-1,RPL31,RUVBL2,H1-6,HMGN4,SRSF4,GOLGA7,SSRP1,BUD23,TOP3B,B3GNT2,MAK16,NGB,H2BC1,CCR1,RPL8,SRSF1,RPS10,LYAR,HMGA1,MRPL18,PPM1B,HNRNPD,ARMC8 |
| 7.532e-07 | -14.10 | ATP2B1 (ATPase plasma membrane Ca2+ transporting 1) | protein interactions | 490 | 216 | 94 | 19454 | 5460 |
EMC2,NTRK2,ATP2B4,RIGI,RAB3B,CSNK2A1,LAMP3,HM13,H2AC4,HSD17B11,RAC2,HRAS,SRPRA,HACD3,STX6,LMAN1,CAV1,FZR1,ARF6,PRNP,CDC42,CFTR,CCND1,PRKCA,RPA2,FGFR1,SSR1,RAB9A,DERL1,RHOU,RPA3,IDH3A,DNAJC5,PNPLA4,RAB2A,ATP1A1,SNTA1,SYNGR1,CCNF,VIRMA,CCR2,RPGRIP1L,RHOJ,ISG15,LGR4,RND3,RPN1,RAB4A,CYP2C9,TMT1A,SSRP1,FLOT1,KRAS,VDAC1,LAMP2,FAM174A,RAB5C,PEX3,RHOG,GJA1,RAB35,LILRB4,DUSP6,FBXO32,PHB1,DIRAS3,HNRNPL,RHOH,SEC62,RND2,H1-5,CLDN4,BET1,HSD17B6,HACD1,RAB5A,AKAP1,PMAIP1,RNF11,STX7,PXMP2,NPTN,EMC1,TOMM40,MYC,RAB11A,LAMTOR1,YWHAZ,RHOB,SEC61B,GPR173,S1PR4,ESR2,MAD2L2 |
| 7.576e-07 | -14.09 | PRPF3 (pre-mRNA processing factor 3) | protein interactions | 9129 | 256 | 108 | 19454 | 5460 |
RPL32,ALYREF,CDC5L,RBM42,TOP1,NKAP,RPS16,FZR1,GPRASP2,RBM17,BRD3,USP15,LSM3,SSX2IP,SNRNP70,H2AC4,TUBG1,SEPTIN7,SNIP1,SNRPG,OLA1,MEPCE,THRAP3,CTNNBL1,H3C1,LSM4,CD2BP2,TP53,NUPR1,CASK,DISC1,CBX3,EIF4A3,VIRMA,TMOD3,AR,CEP70,UBE2H,MAPRE1,NCKIPSD,RC3H2,LSM6,PPIH,PML,PRPF4,RPA3,DVL2,LSM8,RBMS2,SNRNP27,SNRPN,SF3A1,TXNL4A,RPL26L1,TFIP11,LSM2,RPA2,PHB1,LSM5,SNRPD3,SNRPA1,NOP58,HNRNPL,RPS10,TRA2A,DDRGK1,HNRNPA1,DPY30,ZCCHC10,FRA10AC1,IFI16,PSMD3,PRPF19,MPHOSPH6,POU5F1,DDX23,SRSF7,FBXO11,PABPC1,RPL31,SSRP1,CHCHD2,KRAS,CSNK1E,SART3,SNRPE,SMNDC1,SNRPD2,SNRPD1,CPSF1,TACO1,FAU,SNRPB2,SNRNP40,CCDC85B,SNRPB,PRPF31,MYC,BRCA1,EP300,SF3B1,NKAPD1,SLU7,DDX39B,SNRPA,COIL,MFAP1,USP39 |
| 7.576e-07 | -14.09 | ERGIC1 (endoplasmic reticulum-golgi intermediate compartment 1) | protein interactions | 57222 | 256 | 108 | 19454 | 5460 |
UBIAD1,SLC29A1,CCDC47,MRPL11,TFRC,LRRN4CL,YIF1A,SNAP23,RAB1A,PDE2A,SLC6A8,FKBP8,SRPRB,HM13,TMEM199,EI24,DHRS7,AGPAT1,SLC2A1,ESYT1,SRPRA,PTPN1,CAMLG,SLC38A2,TMPO,LMAN1,CAV1,ALCAM,DNAJC1,ARL6IP5,CDK7,RABL3,ARHGAP1,SEC22B,LEMD3,RPA2,SLC12A2,GOLGA5,HSP90B1,ITGA2,SPCS2,TEX264,RDH10,RPA3,FADS2,PRPF4,TMEM209,YKT6,CERS2,DEPDC1B,GORASP2,HMOX2,ATP1A1,EPHA2,ARFGAP3,VAMP3,CCNF,VKORC1L1,VIRMA,GNAI2,COPE,TOMM7,FAF2,HOXB1,MACO1,STBD1,E2F4,CYB5B,RPN1,VAMP2,STIM1,EFNB1,SCD5,HS2ST1,RETREG1,TFG,PPIB,DDRGK1,STX5,WDR6,RAB33A,HNRNPL,RAB1B,INA,RAB6A,DUSP22,TOR1AIP2,PGRMC1,EHHADH,GOSR2,NOTCH2,ARCN1,KCTD12,VAPB,HSPA8,TMEM106B,RER1,TOMM40,VEZT,TMEM38B,SLC38A1,VMP1,LMNB1,FAM83B,ARF1,ATP6AP2,ESR2,ATP5F1B |
| 7.621e-07 | -14.09 | ELOVL4 (ELOVL fatty acid elongase 4) | protein interactions | 6785 | 128 | 62 | 19454 | 5460 |
VAMP1,CCDC167,SEC22A,SEC62,SEC22B,GOSR2,BET1,FDFT1,FAM3C,CMTM7,MMP14,SYNDIG1,SMCO4,VAPB,TMEM243,TMEM203,TMEM254,JAGN1,SLC5A6,SLC7A1,CERS2,HMOX2,VAMP5,FAXDC2,PLN,DPEP1,ELOVL4,CYB5R3,PLP1,CDIPT,FAM177A1,VAMP3,TECR,LYPD6,UBIAD1,INSIG2,YIF1A,BSCL2,UNC50,ERG28,STX8,RAB18,FKBP8,SFT2D2,LEPROTL1,TF,GPR37L1,SLC7A14,ORMDL3,CCR6,EMC6,TMEM19,TMEM199,ADGRE2,BTN2A2,BCL2L1,FXYD6,TMEM11,TMEM42,FA2H,PTPN1,ANKRD46 |
| 7.621e-07 | -14.09 | CDK16 (cyclin dependent kinase 16) | protein interactions | 5127 | 128 | 62 | 19454 | 5460 |
MYC,RAB2A,RAB11A,FAM110B,CUL3,MAP3K21,DEPDC1B,ARHGAP21,LAMTOR1,YWHAZ,RHOB,BRCA1,RC3H2,TBC1D25,CSNK2B,GTF2F1,IRF2BP1,SH3BP4,SIPA1L1,LMNA,FGFR1,SCLT1,HEXIM1,AGAP1,RPA3,INPPL1,RTKN,FAM53C,APPBP2,CYP2C18,MCMBP,CCND3,YWHAG,CSNK2A1,XPO1,LAMP3,YWHAH,EDC3,TIAM1,CDKN1B,YWHAB,CAMSAP2,RAB35,EIF4E2,PPP2CB,SEC23A,ARF6,CDK17,ISG20L2,KCTD3,RHOH,KIF1C,CDK8,CDK5R1,ZYX,CCNY,CDK5,TESK2,KRAS,S100A10,ZBTB14,SRSF12 |
| 7.827e-07 | -14.06 | RALY (RALY heterogeneous nuclear ribonucleoprotein) | protein interactions | 22913 | 335 | 135 | 19454 | 5460 |
TRAF7,RPS20,EIF2AK2,SMURF1,BCCIP,SRPK2,CTSB,DNAJC8,USP14,SMARCA5,FOXA3,RPL7A,ELAVL2,CASC3,UBE2H,SPOP,CWF19L1,MTDH,RHOU,RPA3,AATF,DGCR8,H2AC13,CFTR,RBMS2,ATG16L1,SF3A1,RPL26L1,CDK1,LMNA,SDCBP,RPA2,ZNF326,METTL14,PRR3,SYNCRIP,ACTA2,CDK9,CDC5L,ZBTB2,CAND1,RPL35A,TOP1,CGAS,APOBEC3F,DPP4,MOV10,MAP4,USP15,SNRNP70,CHCHD1,ZC3H11A,HSD17B10,DHX9,SNIP1,RIGI,HUWE1,H3C1,CDC40,HNRNPK,APOBEC3D,OR5A2,THAP1,STRBP,ILF2,NUPR1,TFRC,FOXP3,VDAC2,ESR2,MATR3,SNRNP40,RPL35,RIOK2,BTF3,SNRPB,MYC,HNRNPC,DNAJB6,FBXW11,LMNB1,BRCA1,DCAF4,HSPA8,SF3B1,DDX5,EP300,SNRPA,DDX39B,NKAPD1,HNRNPA0,UFL1,STAU1,RND2,RALYL,PABPC5,ZC3H14,FOXS1,LARP4B,MAP2K1,SKA2,EED,S100A8,RPL9,ERLIN1,DHX15,HNRNPL,RPL7,HNRNPA1,TRA2A,DDRGK1,CTNNB1,RPL6,WWP2,DDX1,HNRNPD,ARMC8,SRSF7,SRSF8,COX8A,RPS24,RPL31,PABPC1,COPS4,HNRNPDL,SSRP1,NUP42,SOX2,RAF1,E2F4,RND3,RHOBTB1,TUBB4B,EZH2,CHMP4C |
| 7.940e-07 | -14.05 | CDK14 (cyclin dependent kinase 14) | protein interactions | 5218 | 46 | 29 | 19454 | 5460 |
KRAS,CCND3,CDK5,CCNY,CAMK1,ACVR1,HEXIM1,CDKN1A,GDE1,CDK17,HNRNPL,MIF,TOP1,EGLN3,SMURF1,VIRMA,HRAS,LDLR,RB1,YWHAZ,CDKN1B,HSP90AA1,FGR,YWHAB,CDKL2,BMPR1B,FBXO7,YWHAG,YWHAH |
| 7.976e-07 | -14.04 | regulation of lymphocyte proliferation | biological process | GO:0050670 | 237 | 105 | 18204 | 5365 |
CCL5,SDC4,SLC7A1,IL12B,MIR185,SOS2,IDO1,IL6,IL21,IL13,CD86,PNP,IL18,RAC2,MIF,SASH3,DHPS,LILRB1,IL12A,FOXP3,CD274,BTN2A2,IL6ST,PRNP,TLR4,CD40LG,LEP,TNFSF8,PELI1,TYROBP,EPO,TICAM1,IL15,LGALS3,MIR181C,CD80,CD28,IL23A,CHRNB2,IL7,MEF2C,IL20RB,TLR9,TNFRSF1B,IL4,LST1,GPNMB,TACR1,PRKCQ,MYD88,IRF1,CD46,LILRB4,CD81,TNFRSF9,MIR21,MIR30B,CD209,VSIR,TWSG1,IGF1,XCL1,IL10,IL1A,SLC39A10,FGF10,CTNNB1,GPAM,TFRC,RPS3,NCK1,SELENOK,PTPN22,PPP3CA,CD1D,HMGB1,IL1B,CD40,BCL6,FCGR2B,MZB1,AGER,TNFSF18,PYCARD,JAK2,IL5,TNFRSF14,IL2RA,CDKN1A,TIRAP,PLA2G5,ARG2,CD38,NDFIP1,TRAF6,SFTPD,AIF1,CCL19,EFNB1,CCR2,IL2,TGFBR2,CTLA4,DLG1,PDCD1LG2 |
| 7.988e-07 | -14.04 | OCRL (OCRL inositol polyphosphate-5-phosphatase) | protein interactions | 4952 | 166 | 76 | 19454 | 5460 |
RAB3B,CHCHD2,KRAS,EIF3E,RAB1A,DHX9,RAB6B,RAB4A,GPX7,AP2S1,SNRPE,SF3B5,TP53,IL1R2,THOC1,RHOH,RAB1B,G6PD,STX6,CDK9,RAB31,PHETA2,RAB35,SPINT2,GJA1,S100A8,WDR82,BPNT2,NME2,SSX2IP,DNAJC7,RAB5C,LAMP2,ATG9A,QPCTL,LAMP3,XPO1,HMGB1,STAU1,FXR2,STX7,RPA3,SNX33,RAB5A,RAB9A,SQSTM1,LSM12,GOLGA5,FGFR1,RPA2,PAK2,SCLT1,BET1,SF3A1,ATG16L1,RAB6A,CDC42,RHOJ,MANSC1,TAB1,RAB14,VIRMA,SCN2B,LMBR1L,AP2M1,RMDN3,BICD2,PLEKHJ1,RHOB,LAMTOR1,AP2A1,NTRK3,RAB11A,AAMDC,MYC,H2BC9 |
| 8.005e-07 | -14.04 | regulation of vascular associated smooth muscle cell proliferation | biological process | GO:1904705 | 93 | 50 | 18204 | 5365 |
MIR1298,MIR185,IL10,IGF1,MDM2,ADIPOQ,TNF,MIR223,SOD2,ADAMTS1,MIR135B,MMP9,MIR34A,MIR15A,PDCD4,DBH,MIR1-1,SRC,APLN,TGFB3,MIR182,JUN,MIR140,BMPR1A,MIR339,CDKN1A,MIR137,JAK2,PTEN,MIR638,MIR448,MIR424,MEF2C,MIR301A,TERT,MIR222,GNAI2,GJA1,MIR208A,MIR20A,CDKN1B,MIR214,MIR17,MIR21,MIR96,MIR146A,MIR130A,PPARG,MIR503,MIR221 |
| 8.012e-07 | -14.04 | MALT1 (MALT1 paracaspase) | protein interactions | 10892 | 67 | 38 | 19454 | 5460 |
HECTD3,SQSTM1,KDM1A,CAMK2G,RBCK1,FEM1C,TRAF2,FEM1A,TAB2,CSNK1A1,OTULIN,STUB1,CCNF,S100A6,NFKBIA,UBE2G2,UBE2N,HNRNPL,UBB,UBE2V2,PRKCQ,APEX1,TNFAIP3,FNDC11,PRMT6,CUL3,USP2,LRRC73,XPO1,COPS5,SUV39H1,BCL10,SMAD4,IKBKB,TRAF6,UBE2H,THTPA,TRIB1 |
| 8.025e-07 | -14.04 | positive regulation of molecular function | biological process | GO:0044093 | 1192 | 426 | 18204 | 5365 |
GSK3A,DVL2,BAD,PTEN,JAK2,PIP5K1A,BCL2L1,LRP6,PLA2G5,TIRAP,PKIB,NR1H2,FGF1,PLAA,TGFBR2,TOR1AIP2,SKP1,MSH6,CCND1,ARRDC3,AR,UBE2N,DIRAS2,SOD1,CARTPT,LMO4,MET,ODAM,ADRB3,ANP32B,KIT,FAS,EIF2AK2,CTSK,BAK1,TXN,VDR,GH1,CCND3,CYFIP2,MT3,CCL24,RFC3,PDCD10,DKC1,EP300,IGF1,APH1A,TAX1BP3,BOK,SNX18,EIF3D,ABCB1,TLR6,SLCO3A1,TANK,KHDC1,DNAJC24,GMNN,DPH3,UBE2V1,IL1B,TNFSF15,TBC1D4,AIFM1,AKT1,LPAR2,PMAIP1,PRKAG1,NUS1,PAX6,GPR65,EDNRA,DSTYK,BCL2A1,SIPA1L1,LCP2,RPS2,UBE2S,DNAJB2,MIR21,RGS10,EMP2,TLR9,MCL1,RGCC,TOM1L1,IL6,BAX,ERP29,GNAQ,MMP9,CD86,ACVR1C,MAGEC2,TBC1D25,IL12B,NEUROD2,PRNP,FLOT1,PPP2CB,PPP1R12A,TRIM34,PSMA6,USP6NL,HSPD1,TERT,CRADD,PIH1D1,DRD1,FGF13,CCL4L1,CHI3L1,SEMG2,CCL2,SYNGR3,MAPKAPK5,DIRAS1,P2RY11,CCL19,XRCC5,NEK2,TRAF6,TLR2,VMP1,RAP1A,UBE2L3,WNT2,HNRNPD,TRIM32,EGLN3,TFRC,TRIM62,TMIGD3,VSIR,CRTC2,SMAD3,ISCU,HDAC6,S100A8,TESC,NKX3-1,FBXW7,TRIM5,STK11,NLRP1,MIR205,SYK,CLU,CD40,CCL23,RALB,RGS6,IL23A,RALGAPA2,COX17,SMARCB1,EIF3E,FGF23,MTPN,PRELID1,FZD4,NIBAN2,STIM1,NTRK2,IFI16,TCP1,NTRK3,RXFP2,CAMK1,NBN,RGP1,RAN,GSTO1,CCL1,GPIHBP1,CACUL1,ROCK1,MIR15A,LGR4,SERINC1,TIAM1,CACNB2,TNNT2,IFNG,TCIM,TAB2,ZC4H2,PHB2,PLCB2,PSEN2,CD40LG,FASLG,HNRNPK,LEP,PIK3CG,THY1,TRIM21,CD200,HNRNPA2B1,FAM162A,IL18,CHTOP,NME1,PTGES3,ANGPT1,WRAP53,SRC,ADRA1A,STAC3,KCNIP2,HDAC5,MAP2K1,AHSA1,CRHR1,COPS5,FCGR1A,MMD,FKBP1A,RASGRP2,CCT2,EDF1,CAV2,ACTN4,ATP1B1,FIS1,TOPORS,HSPE1,DLG3,CCL21,RGN,TRIM22,ARHGAP25,S1PR4,PCNA,ADD1,FGF10,TRIM8,PARM1,TGFB2,CHP1,GTF2B,MAP2K3,CCR7,GREM1,ADRB2,PROX1,C9orf72,TNFSF18,MTDH,HAND2,CCL20,RFC2,TRIM37,PKP4,DHX9,GSTM2,AGAP2,HSP90AB1,NDUFA4,MEF2C,CAV1,CLIC2,TNKS,TAB1,MAVS,IDE,UBE2I,FXN,RPS27L,ARL6IP5,PSEN1,TRIM26,CD4,HTRA2,BUD31,IL4,IFT57,MYD88,IGF1R,SFRP1,FERMT2,ATP1B3,CCL17,MYC,DUSP19,PRDX3,CDC20,PPIA,FZR1,DAPK1,CCL5,ADD2,EFNA3,MMUT,TLR3,EPHA4,TRIM68,HSP90AA1,MAP3K12,STK3,PSRC1,CCL3,PDCD5,TPD52L1,RPS6KA4,SSBP1,HTR2A,BCL10,CCL18,STRADB,NLRP2,RB1,TBC1D10C,DAP,TBC1D13,PSMD10,ZNF622,CDKN1A,RFC4,TMSB4X,F2,CCR2,NHEJ1,CLDN3,TBC1D16,NEUROG2,CTSD,PLSCR1,MIR17,TBC1D17,DDR1,YWHAB,CFTR,TBC1D5,PSME1,CEBPG,CCL25,NLRP3,AZIN2,TRAF2,TRAF1,RFC5,AVPR1B,RPS3,TRIM6,EDA2R,PHB1,MID1IP1,ZC3H15,ADIPOQ,TNF,TBC1D1,DDRGK1,MAP3K11,XCL1,MUL1,IL10,ROCK2,RAF1,CX3CL1,CACNB3,S100A10,CAB39,IL1RAP,PYCARD,HRAS,AGER,DNAJC10,MAPRE2,HMGB1,CORO1C,EPHA2,HFE,CLDN4,B2M,NCSTN,ESR2,EZH2,CHRNA7,PRIM2,ITK,TRIM15,AGAP1,APOC2,RBCK1,IL34,IKBKB,CYP27B1,PPARG,CXCL13,CAP2,PSME2,TRIM52,CDKN1B,GABARAPL2,RHOG,JUP,PRKCQ,MIR1-1,CLEC7A,ITGA6,SCN1B,POR,NEK7,RGS1,DIPK2A,TNFSF10,LPAR1,CCNY,SPPL3,STK4,CCL8,CCL11,KLF4,TRIM27,DDIT3,DLG4,TLR4,MIR26B,PSENEN,TSHR,FGFR1,ADORA3,GHR,PTPN1 |
| 8.102e-07 | -14.03 | POLRMT (RNA polymerase mitochondrial) | protein interactions | 5442 | 205 | 90 | 19454 | 5460 |
TOP3B,LGR4,PDHA1,PNMA2,COX8A,ERP29,KRAS,CHCHD2,KCTD17,MRPS17,IMMP2L,MTRF1,ATG7,DDRGK1,MAP3K14,RHOG,MRPS26,FEZ1,FAHD1,GATD3,NUP35,SYK,NOTCH2,MRPL12,APOBEC3C,EXD2,AKAP1,RAB5A,UFL1,HSCB,STAU1,MTG2,MYC,AUH,GRB10,CUL3,PMPCA,ZNF668,BTF3,MRPS25,RIT1,TACO1,NFKBIA,MTG1,PHF21A,TAX1BP1,FBXO22,ESR2,RPL10,MRPL11,TP53,MAP1LC3B,METTL15,LTBR,FASTKD5,MEPCE,RNF14,GRSF1,KLHL22,SNRNP70,SSBP1,COX4I1,NELL2,SURF6,MRPS23,FAXC,GABRA1,RPA2,FGFR1,TFB1M,ZNF574,HEXIM1,MTRES1,RPA3,TRIM10,SIRT7,AMACR,SQSTM1,GFM1,KDM1A,RPL4,FBXW7,TUFM,RC3H2,UBE2H,FBLN5,FGFBP1,PRKRA,RHOJ,SRPK2 |
| 8.118e-07 | -14.02 | PRAF2 (PRA1 domain family member 2) | protein interactions | 11230 | 102 | 52 | 19454 | 5460 |
ESYT1,ZDHHC15,RAB5C,TSPAN10,LAMP2,DDRGK1,LAMP3,ARL6IP5,ARF6,CAV1,TLCD4,LMAN1,HSD17B11,RPN1,CYB5B,TMEM14B,VAC14,E2F4,MIEF1,DUSP21,PDE2A,RAB1A,CCR5,TSPAN17,LMNB1,LAMTOR1,HMOX2,CSGALNACT2,REEP4,ESR2,DPEP1,LMBR1L,SEC61B,RETREG3,RPA2,CFTR,DUSP22,YIPF5,SEC62,RP2,LPAR1,HSCB,SLC7A1,RNF5,TSPAN5,COIL,RPA3,DUSP9,TMX2,RTN4,DERL1,HSPA8 |
| 8.160e-07 | -14.02 | DDX54 (DEAD-box helicase 54) | protein interactions | 79039 | 353 | 141 | 19454 | 5460 |
APOBEC3C,SYK,PABPC5,BET1,UFL1,FXR2,ZNF692,NOP53,COIL,RAB5A,EP300,PSKH1,BRCA1,LMNB1,RBM27,MRPS25,RIT1,LSM14B,CDKL2,MYC,AUH,CUL3,NOP16,ZNF668,RPL35,FBXO22,ESR2,RPL19,RPL10,PRRC2A,APEX1,RPS9,RPN1,RPS23,RPL18,DNAJC25,ISG15,CHCHD2,KRAS,H1-6,SRSF4,RPL28,MRPS17,RPL31,FGF3,TMT1A,PPAN,RPS24,COX8A,RHOG,DDX23,WDR12,DRG1,IFI16,CLPX,DDX50,RIOX2,MAP3K14,DDRGK1,PGR,RPS10,LYAR,CNTROB,RPL8,RAB35,SRSF1,MAGED2,GATD3,RPA2,LMNA,SSR1,GRM2,RPLP0,MTRES1,RPS14,ATG16L1,TPT1,CDC42,ST7,KLF12,NPM3,DGCR8,RPL4,RPA3,RBM23,SIRT7,RNF113A,MTDH,RAB9A,MECP2,RC3H2,UBE2H,RPL7A,RNASEH1,RPL13A,RPGRIP1L,GRPEL2,SMURF1,SRPK2,SEC63,CCNF,EIF2AK2,ZNF330,PRKRA,CSNK2B,GSK3A,FGFBP1,TFRC,RBM34,HBP1,POLR2G,CASK,SRP72,TP53,MRPL11,LBR,AURKAIP1,RPL15,H3C1,RPL17,RIGI,FAF1,SNIP1,RPL3,SNRNP70,H2AC4,NOL12,RPL10A,DPP4,CSNK2A1,TMED9,DNAJC1,ARF6,FZR1,ZBTB2,SURF6,PTPN1,SYNCRIP,MGME1,KRR1,RAC2 |
| 8.180e-07 | -14.02 | RPL28 (ribosomal protein L28) | protein interactions | 6158 | 437 | 169 | 19454 | 5460 |
CDK7,KLF12,CFTR,RPS14,RPLP0,RPL26L1,ZNF770,SDCBP,RPA2,DCTN4,JUP,ZCCHC17,WWP1,CCDC106,RNF113A,BAP1,RPL27,RPA3,NLE1,BRIX1,HSPA5,RPS15,NPM3,GTF2I,FBXW7,RPL4,PPP1CC,RPF2,RPL7A,PTTG1,UBE2H,CDKN2AIP,TRIM23,RC3H2,PRKRA,PTEN,RPS3,PSPC1,CCNF,METAP2,EIF4A3,RSL24D1,SRPK2,NDN,TAF1D,MAP2K3,MAP1LC3B,LBR,KBTBD4,FBP1,UBL4A,TP53,HBP1,SRP72,TAF2,DNAJC2,RBM34,RPL23A,RPL3,KLHL15,TCOF1,MEPCE,RPL17,DYNC1I1,PAK1IP1,VRK1,COPS5,HDAC6,GPRASP2,API5,ENY2,CENPP,GRSF1,DPP4,EMC4,RPS2,CDK12,MAP4,USP15,SMAD4,SNRNP70,SRP14,RPL32,RCHY1,RBM42,CDK9,DKC1,SURF6,SPPL3,DNAJC1,RPS16,CAND1,MTF1,WDR77,PAFAH1B1,PIH1D1,APOBEC3C,KLF3,EMC9,HSPA8,RAB5A,CMAS,G3BP2,UFL1,STAU1,BTF3,RPS29,MYC,CUL2,CUL3,NSA2,H1-1,RIT1,BRCA1,FTSJ3,RPL37A,SEC61B,ZNF22,CMTR1,ZNF189,RPL19,MATR3,ZCCHC7,RPF1,RPL35,RPL7L1,MAK16,H1-3,ANAPC13,ZNF397,B3GNT2,TRMT1L,RPS11,POLR2C,RPL18,RPS23,EZH2,PDHA1,CHMP4C,TRIP4,SAR1B,KRAS,TNF,TRIM37,VDAC1,XPO1,DDRGK1,CTNNB1,MAP3K14,DDX50,WWP2,RPL6,RB1CC1,MAGOH,DRG1,RPL23,WDR12,AGR2,RPLP2,RPLP1,FOLR1,RPL9,RPL8,PHB1,KIAA0232,RPS10,PCSK9,DYNC1I2,RPL7 |
| 8.180e-07 | -14.02 | SPTAN1 (spectrin alpha, non-erythrocytic 1) | protein interactions | 6709 | 437 | 169 | 19454 | 5460 |
DHX9,PALM2AKAP2,RPL17,TGFBR2,HNRNPK,NEDD8,TSSC4,MAP1LC3B,TP53,UBL4A,RNF8,FURIN,NUPR1,CAPN2,ILF2,DISC1,CAPZA2,NEFL,TFCP2,TFRC,RAC2,TES,ADD1,ACTA2,HRAS,CDC5L,CAV1,CDK9,TMPO,STX6,HDAC6,COPS5,KARS1,DPP4,CNN3,SMCHD1,SHC1,SNRNP70,H2AC4,TUBG1,PRKCB,GRIA2,SIRT7,RPA3,RHOU,BAP1,CRYZ,HSPA5,PIAS1,NUCKS1,SMC4,CERS2,CFTR,CDC42,CAPN1,SPTBN1,UBE2M,TMOD1,METTL14,RPA2,LMNA,JUP,PAK5,PTP4A2,MSN,TRIM24,PTEN,UBASH3B,CTNNA1,CTTN,EIF4A3,CCNF,VIRMA,NMI,DYRK1A,SRC,SMURF1,RHOJ,DAPK1,CTSB,COPE,DNAJC5,USP14,H2BC9,UBE2H,MAPRE1,RC3H2,RPS24,JAK1,EWSR1,FLOT1,FANCG,VDAC1,TRIM37,LASP1,KRAS,KIF2A,ISG15,PCDH19,TXNRD1,RAF1,TOP3B,B3GNT2,TAF10,SMARCB1,RND3,CHMP4C,RAB4A,GJA1,RAB35,HSP90AB1,DIRAS3,SUMO2,RHOH,DBR1,CTNNB1,EXOC1,YWHAH,YWHAG,SAV1,IFI16,BCL2L1,MAGOH,CBL,MED4,PPM1B,AGR2,RHOG,JADE1,RAB5A,GPHN,DDX39B,SAP18,STX7,STAU1,NSFL1C,UFL1,CYFIP2,RND2,PPP1CB,AKIP1,WDR77,TOMM22,KLC2,PPT1,PSMB7,FAU,DES,ESR2,PSMB6,ACTB,TAMM41,STAT1,MCM3,BTF3,SFN,CUL3,RAB11A,HNRNPC,MYC,CREBBP,MCAT,NSA2,HSP90AA1,BRCA1,LMNB1,RHOB,ATG3,YWHAZ |
| 8.212e-07 | -14.01 | UBE2I (ubiquitin conjugating enzyme E2 I) | protein interactions | 7329 | 615 | 227 | 19454 | 5460 |
MAP2K1,CTBP1,PCGF2,EP300,DDX5,HDAC5,FOS,SPECC1L,XRCC5,DDX39B,HIRA,HNRNPC,LMO2,MYC,CREBBP,RBBP8,SF3B4,ZMYM2,NFKBIA,DES,APEX1,RORB,TRIM29,ZCCHC7,MATR3,STAT1,NUDCD3,TRAF2,RANBP1,TAF10,KLHL12,HGS,STMN2,TRIM21,TOP2B,TFG,NFE2,MAPK1IP1L,SATB1,RUVBL1,PELI1,KRAS,ZBED1,XPO1,WWP2,HSPB1,DRG1,DDX1,AGR2,ZHX1,SRSF1,ELK1,SUMO2,MITF,SUMO3,RNF144B,CFTR,XBP1,CD2AP,SUMO1,SUPT7L,DYRK2,RPRD1B,HSPB2,PML,TRIM3,BAP1,POLR1H,UBE2K,KDM1A,CFL2,MAT2A,SUGP1,UBE2H,CALU,POU1F1,ANAPC4,DTL,RC3H2,TRIM23,SPOP,CSNK2B,CREB1,NMI,NR1I2,PLAGL1,TRIM54,IKZF5,EGR2,TP53,NUPR1,PHC1,PSMC3,TAB2,CAPN2,SH3GLB1,CRABP2,TFCP2,DHX9,ZNF451,BHLHE40,SNIP1,RUSF1,HNRNPK,NUP107,ZNF24,TSNAX,NXT2,SMAD4,CDK6,RNF128,CDR2L,ALYREF,BEND5,AGTRAP,LNX2,KLF3,PPARG,RNF10,RABAC1,RNF40,CUL3,RIT1,FHIT,LMNB1,BRCA1,RHOB,FAS,RAN,TSN,ACTB,SIAH1,JUN,NUP153,RAF1,RWDD3,FHL3,PRPSAP1,PCNA,ATF3,MORC2,MEF2C,SSRP1,SRSF4,ZBTB16,FATE1,SIAH2,CREBL2,HNRNPA1,MARCHF5,HMGA1,BCL2L1,CAMSAP2,STX1A,HNRNPD,CDKN1B,TRAF6,THY1,TSG101,RPL8,NUP35,CACYBP,RPL7,NOP58,DPPA2,MX1,EDF1,DCTD,SNAI2,CHMP1A,LMNA,CDK1,TMEM209,MEF2A,NHP2,PIAS1,HMGB1,USP8,GTF2I,B2M,AR,NONO,ZCCHC12,CSGALNACT2,CSK,MAPRE1,PTEN,TRIM24,UBE2I,PRKRA,TRIM27,EIF2AK2,CTNNA1,CCNF,MRPL53,JUNB,NR1H2,KCNIP3,CEBPE,THAP1,SOX9,PPARA,DDX39A,NDUFA2,ZBTB26,TOPORS,SEPTIN7,CACUL1,RNF133,GLUL,FAF1,RIGI,TRIM63,CAMK2G,RNF115,SEM1,ZMYND11,MUL1,SLC2A1,RB1,ETV6,ZBTB2,MDM2,AKAP17A,TOP1,TSC22D3,COG1 |
| 8.373e-07 | -13.99 | negative regulation of angiogenesis | biological process | GO:0016525 | 154 | 74 | 18204 | 5365 |
MIR145,SYNJ2BP,ROCK1,CTNNB1,MIR15A,MIR143,AGO1,MIR34A,ADAMTS1,MIR505,SPRED1,IL17F,TNF,MIR106B,EFNA3,MIR34B,MIR640,ROCK2,TGFB2,MIR185,MIR24-1,MIR1298,KLK3,EMILIN1,KLF4,MIR10A,FASLG,MIR361,MIR939,KRIT1,PRL,VASH1,MIR205,MIR495,MIR885,MINAR1,EPHA2,MIR34C,HGS,MIR16-1,GTF2I,MIR29A,MIR424,MIR29C,MIR137,CXCL10,ATP2B4,MECP2,STAT1,PML,MIR125A,MIR212,CCR2,MIR503,MIR221,NIBAN2,PPARG,MIR375,PGK1,MIR492,MIR146A,MIR21,MIR30B,MIR214,MIR17,MIR193A,MIR20A,GHRL,MIR377,MIR222,SLC12A2,MIR30E,RGCC,GADD45A |
| 8.423e-07 | -13.99 | SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4) | protein interactions | 6597 | 407 | 159 | 19454 | 5460 |
CSNK1A1,ADNP,PALS2,PPARG,CDKN1A,WDR77,ACTL6A,SAP18,STAU1,DDX5,DDIT3,EP300,NEUROG2,FOS,HIRA,SMARCD3,SETD7,RIT1,SP1,BRCA1,LMNB1,CPSF2,IRF1,SMARCE1,HNRNPC,CUL3,MYC,CREBBP,APEX1,ESR2,CBX5,ACTB,SNRNP40,RBBP4,MED17,RFXAP,STAT1,STAT2,GTF2F1,MCPH1,PRMT5,PELO,NFKBIA,MOB3C,TAF10,RBPJ,MTA2,SMARCB1,STMN2,TUBB4B,EZH2,SAP30,SOX2,E2F4,CSNK1E,RAF1,SSRP1,PAX6,GTF3C3,ASF1A,KRAS,RBBP7,EWSR1,ATF3,HNRNPA2B1,TOP2B,BCL7B,MPHOSPH6,HSPB1,LHX2,CTNNB1,ATG7,BCL7C,RAB5C,WWP2,PIK3R1,BAZ1B,HMGA1,ATXN10,SUMO2,POLR3F,BRD9,EED,FBXO32,MYEF2,PHB1,SIN3A,KLF4,PARD6A,E2F6,GRM2,HSP90B1,RPA2,SF3A1,SS18,BCL6,MBD3,NUCKS1,FBXW7,HMGB1,HDAC3,ELOF1,PML,SIRT7,RPA3,STK11,SMAD2,NONO,AR,GMNN,DEPDC1B,RUNX1,SMARCA5,DEK,JUNB,VIRMA,SCML2,CHMP5,NR1H2,CD47,STAT5A,MACROH2A1,ALB,PTEN,CTTN,ZNF330,UBN1,CREB1,CCNF,NFE2L2,CDK8,CBX3,SOX9,H2AX,ING1,RAP1A,TP53,MDC1,KPNA2,H3C1,PPP1R12A,SNIP1,BRD3,TOPBP1,KPNA1,SNRNP70,NR4A2,E4F1,ZMYND11,CSNK2A1,COPS5,CDC5L,MDM2,TOP1,KLF1,CAND1,RB1,H2AZ1,SMAD3 |
| 8.449e-07 | -13.98 | PRKCZ (protein kinase C zeta) | protein interactions | 5590 | 398 | 156 | 19454 | 5460 |
GLO1,API5,GAPDH,PPIL4,HDAC6,CSNK2A1,CALR,TIAM1,COX4I1,AIFM1,STT3A,EEF1B2,HRAS,MRPL50,CAND1,EEF1A1,PPIF,MAP1LC3B,CCT5,MRPL49,HINT1,SLC16A1,DDR1,MRPL52,TLR4,MAP1B,PRDX4,MSH6,PTGES3,EIF3E,OLA1,PSEN1,HSPE1,CSE1L,NEDD8,HUWE1,TUFM,PPP1CC,PRKACB,CFL1,SUB1,SLC25A1,AKT1,AKT3,CALU,OAT,ATP1A1,TLR9,STK24,ATP1B3,RPS12,ACAT1,GSK3A,GANAB,CSNK2B,PSMC5,UQCRC2,MRPL53,STUB1,PDCD5,SRC,TECR,PRKCE,SLC25A4,F11R,GPX1,DAPK3,UQCRC1,CDC42,PSMC4,STAT6,PARD6A,PRKCA,HSP90B1,RNF146,RPA2,CDK1,SQSTM1,PRDX6,PGK1,GID8,SOD1,GABARAP,HSPA5,HMGB1,STK38,NPM3,YWHAH,YWHAG,PPFIBP1,HNRNPA1,XPO1,PRDX1,PDIA3,HSPB1,YWHAB,ARMC8,PPP3CA,AHSA1,TRAF6,FKBP4,MRPL18,IKBKB,RPLP1,FEZ1,HSP90AB1,PPIA,SUMO2,HNRNPL,EEF2,ACTN4,RAF1,MARCKSL1,GDI2,TUBB4B,BAG2,PDIA6,JAK1,TRIM21,PCNA,AKT2,SLC25A5,KCTD17,VDAC1,TRIM26,CHCHD2,PSMD1,H1-1,MDH1,HSP90AA1,SP1,YWHAZ,CCT2,BLVRA,SEC61B,SNRPD2,AP2M1,SNRPD1,CYB5R3,VDAC2,DYNLL1,TUBB,TAB1,PTPRZ1,CAVIN2,MRPL12,PRDX3,PGRMC1,H1-5,SLC25A3,MAP2K1,HADHA,HSPA8,TMEM160,PEBP1,EEF1G |
| 8.449e-07 | -13.98 | MFN2 (mitofusin 2) | protein interactions | 9927 | 139 | 66 | 19454 | 5460 |
NAA15,TOP3B,NUDCD3,CFAP36,CSTPP1,PSMC3,BAG2,TTC4,PSMA1,PSMA5,KRAS,HUWE1,PSMA2,FKBP8,EDEM1,SLC25A46,MARCHF5,TPM3,MFN1,HDAC6,PSMD7,FKBP4,VCPIP1,PSMB5,PSMB4,UBE2N,AIP,THY1,PSMB1,TRAK2,DIPK2A,OCRL,EGLN3,CACYBP,PSMB3,PSMC4,GHITM,SAMM50,CTBP1,RPA2,PSMB7,PIH1D1,EXD2,TMEM160,TTC1,PSMA3,SQSTM1,MAVS,AKAP1,TXNL1,NSFL1C,HSCB,YKT6,HSPA5,PSMC1,C9orf72,ST13,PSMD1,RIT1,UBE2H,PSMA6,PSMC5,PSMD6,PSMD4,PSMB6,UBB |
| 8.518e-07 | -13.98 | GJA8 (gap junction protein alpha 8) | protein interactions | 2703 | 158 | 73 | 19454 | 5460 |
VAMP5,GJB2,MGST2,NDUFB6,ARL6IP6,SEC22C,TMEM100,REEP6,PLN,CCNF,SELENOT,PLP1,CYBC1,LRRC8A,SEC22B,CLDN4,SLC35F6,STXBP1,CTXN3,CCDC167,FGFR1,SMCO4,VAPB,FAM3C,LEMD3,FDFT1,SLC39A9,NDUFC2,TMEM243,STX7,PMP22,SLC38A7,CLEC1A,SLC13A5,TMBIM6,TMEM107,RNF152,AGR2,DOLK,TMEM42,FXYD6,NDUFB8,AQP4,C2CD2L,DEFB121,PSME2,SEC23A,COX20,SLC66A2,GJA1,TWSG1,TMEM97,INSIG2,PGAP2,MFSD6,TMEM45A,MAP1LC3B,SLC29A1,SFTPC,SLC35F1,TMEM182,STX12,NDUFA12,PSME1,NDUFB5,RUSF1,STX8,YIF1A,TMEM147,SLC39A7,ATP6V0B,TMEM60,LEPROTL1 |
| 8.558e-07 | -13.97 | COX6B1 (cytochrome c oxidase subunit 6B1) | protein interactions | 1340 | 97 | 50 | 19454 | 5460 |
ATP1B1,PRDX1,RAB5C,COX5A,VPS26A,AIFM1,COX4I1,COX7A1,PLGRKT,SLC25A12,COX14,CAV1,RMND1,SPPL3,PRNP,APOO,COX4I2,SNAP29,POLR2G,NDUFS6,CLPB,S100B,SFXN1,RIGI,KRAS,COX6B1,MYC,RIT1,CHCHD4,ACOX1,CCNF,UQCRC2,CYB5R3,STUM,UQCRQ,PARL,SRC,YIPF5,TIMMDC1,DYRK2,KLF3,RPA2,COX6C,SYS1,COX7B2,TMEM220,NDUFC2,XRCC5,SLC25A51,PHB2 |
| 8.564e-07 | -13.97 | MRPS24 (mitochondrial ribosomal protein S24) | protein interactions | 64951 | 271 | 113 | 19454 | 5460 |
PDSS2,EXD2,NGRN,MRPS7,RANBP10,UFL1,HSCB,TIMM29,RPS9,CCDC90B,MTG1,TACO1,PARL,KBTBD6,RPL10,DYNLL1,RPL35,PCCB,PMPCA,AUH,MYC,MTG2,MCAT,HTRA2,MRPS25,COX8A,MRPS11,SRSF7,MKLN1,HINT2,HECTD3,MAEA,HSPD1,PREPL,IMMP2L,MRPS17,ZNF263,RPL18,PDHA1,NUDT19,GATD3,SRSF1,HDHD5,RMND1,COX14,TRA2A,DDRGK1,MMUT,HNRNPA1,RPL6,MRPS35,MTRF1,ARMC8,MRPS26,MRPL18,RHOG,GFM1,GID8,RPA3,GID4,CRYZ,OGDHL,FBXW7,RPL4,SLC25A51,RBMS2,KLF12,HAUS2,KLF4,MTRES1,ZNF574,MMADHC,RPA2,MRPS34,MRPS28,CCNF,MRPS21,TUFM,ZMYND19,UBE2H,DNAJC19,YPEL5,SPOP,MRPS16,MRPS18B,RPL23A,CLPB,RPL17,MRPS18C,MEPCE,FASTKD5,CHDH,MRPS33,METTL15,AURKAIP1,APOBEC3D,MRPL11,GFM2,TRMT10B,SSBP1,AIFM1,MRPS9,SYNCRIP,SRP14,MRPS23,SURF6,RBM42,FZR1,E4F1,GRSF1,TMEM70,CHCHD1,SNRNP70 |
| 8.564e-07 | -13.97 | FASTKD2 (FAST kinase domains 2) | protein interactions | 22868 | 271 | 113 | 19454 | 5460 |
EIF2AK2,CCNF,MRPL53,ACAT1,MRPS28,RHOJ,PYCR2,CAP2,NDUFAF2,TUFM,MRPS16,RPA3,RHOU,SQSTM1,GFM1,MRPL41,NME4,MRPL20,CFTR,RBMS2,CDC42,MRPS34,RPA2,MTRES1,ZNF574,MRPS9,AIFM1,SSBP1,PRR3,MRPL50,MRPL24,MRPS23,ATP5PD,RBM42,GRSF1,SNRNP70,CHCHD1,MRPL52,MRPS18B,MRPS33,MRPL22,FASTKD5,GBE1,NDUFA2,MRPL11,METTL15,BCS1L,DUSP1,PPIF,HADH,NDUFS3,MRPL49,MRPL51,GFM2,ILF2,DLST,MTG1,CCDC90B,DPEP1,TACO1,MRPL13,PARL,NDUFAF4,PYCR1,PMPCA,MYC,MTG2,AUH,MRPS25,CIRBP,MCAT,EXD2,NGRN,HSCB,NDUFS2,MRPS7,FTL,PABPC5,MRPL12,RND2,MRPS18A,ATP5PO,NDUFA5,ATP6V1A,FAHD1,GATD3,NDUFS8,MRPS35,MTRF1,NDUFV2,MRPL9,HNRNPA1,RHOG,MRPS26,RBM3,HSPD1,SRSF7,COX8A,MRPS11,HINT2,ETFA,KGD4,NUP42,ATP5F1D,SSRP1,IMMP2L,MRPS17,ETFB,NDUFS6,PDHA1,RHOBTB1,RND3,NDUFA12 |
| 8.585e-07 | -13.97 | CYCS (cytochrome c, somatic) | protein interactions | 54205 | 169 | 77 | 19454 | 5460 |
MDH1,BAX,RBM27,RBM15B,MTPN,GSTK1,STK38L,FMC1,MYC,SUGP1,PARL,PRRC2A,VIRMA,PRDX2,TRIM24,PTPMT1,ACAT1,CYB5R3,GLRX2,RSRC1,OPTN,CCNF,VDAC2,CYC1,RNF7,RPA2,MED23,CCNA2,SNRNP27,UQCRC1,UBA52,PHB2,NME4,MTDH,HSPA8,NLE1,RPS28,CSTB,RPA3,DDX46,HSPB1,BCL2L1,CDK12,MED4,TRAF6,ACP6,ETFRF1,DDRGK1,HDAC6,SELENOS,CAV1,EGLN3,SPPL3,TES,FAAP100,CYB5A,UBE2N,COQ10B,PHB1,AIFM1,ALDH1A3,CYB5B,DCUN1D5,EZH2,RP9,APOO,HADH,COX4I2,CYB5R1,DHX38,RIGI,IMPA2,VDAC1,KRAS,ARGLU1,SFXN1,SNIP1 |
| 8.819e-07 | -13.94 | PSMB5 (proteasome 20S subunit beta 5) | protein interactions | 5693 | 228 | 98 | 19454 | 5460 |
PSMB7,PIH1D1,PSMB3,PRDX3,DDI1,PSMC1,SKP1,HDAC5,HSPA8,PSMA3,POMP,PSMD14,BRCA1,HSP90AA1,RIT1,MYC,PSMA4,PSMD1,CPSF2,BAG3,PSMD4,PSMD6,PSMB6,RAN,SNRPD2,MOB3C,B3GNT2,ACTN4,ISG15,PSMA1,KRAS,PSMA2,CDK20,PSMD12,SAR1B,TOP2B,UBE3A,ELP6,AGR2,TRAF6,PSMD10,PDIA3,PSMD3,PIK3R1,SNRPA1,HSP90AB1,PSME2,PSMB4,RPA2,GRM2,UBE2M,HEXIM1,PSMC4,CFTR,PAAF1,DESI1,MARS1,RPA3,SQSTM1,SPOP,ATP1A1,PSMG3,UBE2H,MAT2A,PSMB2,CEP85,FBXO7,NTAQ1,AR,USP14,ADRM1,SLC25A31,VIRMA,CCNF,PSMA6,PSMC5,PSMC3,RAD23B,PSMB9,UBR7,PSMA5,PSEN1,MEPCE,PSMB10,CAPZA1,FKBP8,MAP1B,PSME1,PSMG2,PSMD7,CLP1,KARS1,MOV10,FZR1,TOP1,PRNP,CD274,PSMB1 |
| 8.855e-07 | -13.94 | Eif3e (eukaryotic translation initiation factor 3, subunit E) | protein interactions | 16341 | 110 | 55 | 19454 | 5460 |
CGGBP1,RPS10,RPS16,HP1BP3,RPL12,RPL8,RPL32,RPS2,RPL23,RPL10A,EIF3D,SPATS2L,RIOX2,RPL6,RPS13,RPS4X,RFC2,RPL17,RPL23A,RPL3,RPS24,PPAN,TOP2B,RPS11,GTPBP1,RPS7,RPL15,RPSA,RPL22,RPL10,RPL19,ZNF622,RPL13A,RPL37A,RPS12,RPS20,RPS3,FAU,EIF3K,IGF2BP1,EIF3G,TBC1D16,RPS29,SMARCA5,RPL7A,BRIX1,RPS15,RPL4,RPL27,PNO1,RPLP0,TRMT112,EIF3J,RPS14,RPL27A |
| 8.932e-07 | -13.93 | ACIN1 (apoptotic chromatin condensation inducer 1) | protein interactions | 22985 | 277 | 115 | 19454 | 5460 |
NUPR1,FURIN,DHRS7B,KLHL26,RIGI,RPS13,THRAP3,CAMKV,DHX9,SEPTIN7,ZC3H11A,SNIP1,BRD3,CD9,SNRNP70,ZMYND11,API5,HDAC6,SNAP91,CSNK2A1,ZBTB2,CAV1,RBM42,CDK9,TOP1,NKAP,VTI1B,ALYREF,SRP14,PRKCA,RPA2,LMNA,DENND2D,TPT1,FUT8,SF3A1,HMGB1,RNF113A,MTDH,SIRT7,BANF1,RPA3,BTBD10,UBE2H,CSGALNACT1,RRP7A,ELAVL2,NRP1,PPP1CC,AR,PCBD1,SUB1,SRPK2,GSK3A,EIF4A3,ZRANB2,CHMP4C,BZW2,HDAC11,PDHA1,NFKBIL1,EZH2,LGR4,E2F4,SUPT5H,RAF1,TOP3B,GOLGA7,SSRP1,SRSF4,KRAS,RTCB,SRSF7,ARGLU1,RPL31,MAGOH,DDX23,YWHAG,HNRNPA1,IFI16,DHX15,RPL7,SUMO2,SNRPA1,COPS2,EED,TMEM184B,TRMT112,ARMCX3,BET1,PABPC5,SAP18,STAU1,EEF1G,PAFAH1B2,UFL1,HSPA8,SF3B1,NKAPD1,DDX39B,PYM1,SNRPA,SNRPB,RIOK2,PSMD1,CUL3,CFAP20,MYC,ESR2,SNRPB2,NDUFAF4,SNRNP40,CAVIN2,SMU1,DLST |
| 8.940e-07 | -13.93 | negative regulation of cell growth | biological process | GO:0030308 | 170 | 80 | 18204 | 5365 |
EI24,GSK3A,CDKN2D,VGLL4,BMPR2,SERTAD3,ESR2,DCUN1D3,RB1,FGF13,CDKN2AIP,NDUFS3,CAV3,RGMA,RERG,CDKN1A,NRP1,MECP2,BST2,SPHK2,CYP27B1,PML,IFRD1,OSGIN2,TP53TG5,DNAJB2,CGRRF1,RTN4,CDKN1B,GJA1,BRCA1,PI16,TNR,G6PD,SESN2,MSX1,SFRP1,HYAL2,CCN3,CDKN2C,CRYAB,PHB1,ING1,BTG1,MT3,CRLF3,RBBP7,NAIF1,FOXP1,TP53,PPT1,MUL1,TGFB2,SMAD3,EAF2,HDAC6,TRIM46,FBP1,TMEM196,TOMM70,SEMA5A,SERTAD2,GREM1,CCAR2,ADIPOR1,SMAD4,STK11,JADE1,PPARA,PSRC1,CCDC85B,FRZB,MINAR1,RGS2,CDK5,SPP1,ENO1,BCL6,ACVR1B,SH3BP4 |
| 9.001e-07 | -13.92 | STRAP (serine/threonine kinase receptor associated protein) | protein interactions | 11171 | 251 | 106 | 19454 | 5460 |
PIH1D1,LARP4B,PPT1,PSMB7,PSMB3,GH1,STAU1,GPC1,UFL1,EP300,HSPA8,HDAC5,SNRPA,RIT1,SP1,BRCA1,MYO6,CCT2,FYTTD1,SNRPB,BTF3,CUL3,PSMA4,PBLD,MYC,PSMB6,TSN,PSMD6,SNRPD2,SNRPD1,SNRPE,MOB3C,NME1,EZH2,SOX2,ACO1,TOP3B,RAF1,B3GNT2,RPS27A,RBBP7,HNRNPF,G3BP1,KRAS,RUVBL2,LSM14A,PSMD10,AGR2,DDRGK1,HNRNPA1,XPO1,WWP2,PSMD3,CCT7,SUMO2,SNRPD3,DYNC1I2,PHB1,LUC7L3,MTRES1,UBE2M,METTL14,RPA2,RPRD1B,CFTR,HSPA5,FBXW7,RPA3,BAP1,UBE2H,IGF2BP1,SMAD2,OAT,GEMIN8,VIRMA,RPL22,SMURF1,ADRM1,PTEN,RPS20,CCNF,RNF8,NUPR1,GEMIN7,CAPZA2,CHAMP1,TP53,SMN1,CAPZA1,TGFBR2,HUWE1,PC,ABCE1,MAP1B,TSNAX,MAP4,SNRNP70,RPL24,HDAC6,COPS5,MOV10,KLF9,PRNP,FZR1,LDLR,SMAD3 |
| 9.151e-07 | -13.90 | modulation of chemical synaptic transmission | biological process | GO:0050804 | 494 | 195 | 18204 | 5365 |
NCDN,SLC6A4,S100B,MECP2,SLC38A1,NCSTN,SLC38A2,CHRNA7,CHRNB2,PRRT1,SNCG,NR2E1,SLC6A6,PDE9A,CPLX1,CAMKV,SV2B,CLSTN3,NTRK2,PAFAH1B1,PPFIA3,ARF1,NLGN1,PLCL1,NTF4,STAU1,GABBR1,P2RY1,MTMR2,DAG1,LARGE1,ADRA1A,ADORA1,ADORA3,NETO1,HOMER1,BACE1,ATF4,SLC4A10,SQSTM1,DLG4,VAMP2,ATAD1,DISC1,SYP,CCL2,SYBU,JPH4,CACNB4,GUCY1B1,DRD1,LGI1,IGSF11,ADNP,NPY5R,DMPK,CD2AP,CD38,NEFL,RAB5A,FXR2,NLGN2,SLC12A2,INA,GRM2,PICK1,CCR2,CDH11,TNF,ADIPOQ,SLC7A11,CX3CL1,KCNJ10,GRM8,TMEM108,ASIC1,RAP1A,EIF4A3,CX3CR1,LRRTM2,SNX14,YTHDF1,MME,STX1A,NTNG2,CDK5,TBC1D24,NOG,HDAC6,AGER,HRAS,PLG,CHRDL1,ACHE,TYROBP,SIPA1L1,USP8,SNAPIN,VPS18,UCN,CHMP2B,MEF2C,SYN3,PLCB1,OPHN1,RTN4,TACR1,NGDN,MIR342,MIR421,NPTN,GRIA2,CBLN2,MIR324,ANAPC2,SYT4,MIR30B,CACNG3,PTN,EGR2,PSEN1,CASK,YWHAG,KCNB1,LRRTM1,EPHA4,RIMS3,AKAP12,HCRT,LRRC4,PREPL,UBE3A,EIF4E,ABHD6,BGLAP,PCDH17,CDC20,DLGAP4,MIR142,YWHAH,CA2,HTR2A,CPLX3,GRIK1,GRM1,PRNP,NEUROD2,FLOT1,SNAP25,SLC1A3,CHRM1,STXBP1,PTEN,JAK2,EIF4EBP2,USP46,SYNGR1,PRKCE,CPLX2,PRKCB,MIR545,SLC4A8,GRID1,RAP1B,GRIA1,GHRL,MIR320A,TNR,KIT,GNAI2,PAIP2,CBLN1,ATP1A2,RAB3A,CNR1,KRAS,RIMS4,FRRS1L,PPFIA2,NSG1,SLC1A1,MIR95,MAP1B,OXTR,RETN,P2RY4,SLC6A1,PPP3CA,WNT7A,FAM107A,DKK1,IL1B,RNF167,DRD3,ADRB2 |
| 9.169e-07 | -13.90 | TBCA (tubulin folding cofactor A) | protein interactions | 6902 | 82 | 44 | 19454 | 5460 |
GLRX5,EZH2,TUBB4B,MSRB3,HINT1,EIF4EBP2,KRAS,GUK1,MPST,AHCYL1,MARCHF5,COX5A,TAF9,COX4I1,GATD3,LYRM2,PRNP,CAV1,LAP3,CDC42,GSTP1,CSTB,RPS28,SOD1,BAP1,PRDX6,ARFIP1,COX17,BCL6,CRYZ,PMPCA,MYC,ISCA2,MTPN,FXN,MDH1,ENO1,CCNF,PSPC1,TRIM24,TXNDC12,GDPGP1,CTSB,CLIC4 |
| 9.235e-07 | -13.90 | protein modification process | biological process | GO:0036211 | 2058 | 701 | 18204 | 5365 |
FAM20C,FEM1B,SEPHS1,COL3A1,MSL2,MARCHF9,CFAP20,RNF167,RNF8,ISG15,GALNT4,ST6GALNAC3,KLHL15,NEDD8,RLIM,DUSP3,GTF2B,UCHL3,TRIM8,PGAP2,OTUD7B,LORICRIN,AANAT,RNF11,CBL,ALG11,PCMTD1,ERO1A,PDF,PPIG,CSNK2A1,HCST,PTPN5,DCAF5,GXYLT1,TNNI3K,TOPORS,OS9,PRPF19,ING5,PPTC7,KDM1A,ANAPC11,OTULINL,RIMKLA,TLR7,ZBED1,FKBP1A,CTTNBP2NL,XXYLT1,CTU1,VIPAS39,SNRK,PRMT2,MAP2K1,PPP1CC,PMM2,HERC3,SHPRH,STK3,RNF34,SETD7,UST,MAP3K12,ETFBKMT,CDC16,DYRK2,TLR3,TRIM68,EPHA4,TUSC3,ZDHHC15,SOCS2,PGAP3,PPIA,FZR1,ABHD10,IGF1R,PPP2R5E,FBXO32,CSNK1E,RCHY1,MTMR6,IL4,TRIM54,SOCS5,NTMT1,SPOP,KLHL3,FAM98A,IGFBP3,PDP2,FXN,CSNK1G3,ALG5,FBXO25,USP5,STAMBPL1,RNF7,BCKDK,CDK5,KLHL9,STUB1,DUSP10,CSKMT,HECW1,RNF5,KDM2A,MED11,EPHB6,MUL1,PPT1,DUSP18,CDK8,KCTD9,GALNT12,PPM1D,RNF133,MAPKAPK3,OTUD6A,CSNK2B,GGCX,FUT8,CDK9,TOP1,RNF141,TNFAIP1,ILK,RNF152,PPIB,PTPN1,LARGE1,TLR4,TSSK1B,TMEM165,FBXO30,CRBN,ST3GAL4,B3GALT1,ST6GAL1,SUMO3,VCPIP1,STK4,MDM2,PIGC,AGA,CDC26,ANAPC16,PTAR1,NEK7,MAP3K3,CAMKV,NAA35,PPP2R1A,B4GALT3,PCMTD2,ASB7,TRIM52,ALG2,PPWD1,KLHL22,NQO1,GMPPB,PPP2R3A,UFL1,SIAH1,TRIM15,PTPN4,TRIM44,RBCK1,METAP2,HINT1,RNF139,DET1,ATAT1,SIAH2,DYRK1B,AKT1,PPP3CA,HERC4,KBTBD2,FKRP,DNAJC24,UBA52,DUSP26,SIRT7,FBXO9,FEM1C,PPP1R11,UBE2W,CLK4,B4GAT1,TNFAIP3,KIT,SPSB1,CPE,COQ8A,DOLK,UBE2D1,TGFBR2,PAK2,TRIM63,B4GALT1,USP46,TSG101,PPP5C,E4F1,PPP3R2,DOHH,PRKCE,FN3KRP,EGLN2,SPRR1B,B3GALT2,SYVN1,CDK5RAP3,FUT1,DHPS,UHMK1,AKT3,COPS2,PPP2CB,PPP1R12A,HECTD3,HS3ST5,AKT2,DAPK3,KLHL25,RNF181,CLIP3,OXSR1,ZDHHC14,UBE2K,ACVR1C,DCAF4,TRAF3IP2,USP38,METTL18,PPP2R5A,ZBTB16,UBA3,HDAC3,ADM2,ATG7,ST3GAL2,B3GALT4,UBE2S,B3GALNT1,TNIK,SRD5A3,AQP11,RIMKLB,NMI,URM1,GFPT1,PRKAG1,NUS1,MED27,SLC35C1,PIGW,OTUD6B,VPS18,DUSP21,ARFGEF1,MED10,ACVR1B,BFAR,PPME1,SYK,TRIM5,PPIC,ALKBH4,STK11,ZDHHC17,HDAC6,S100A8,DPM2,NME2,FBXW7,PARP2,WEE2,KCTD10,DCUN1D5,LACRT,EGLN3,YES1,BIRC2,DUSP1,KBTBD6,ASB1,PRKAB1,RLIG1,GLUL,TRMT112,UBE2L3,TRIM32,FKBP4,ST8SIA5,TLR2,MYLIP,DUSP9,PPM1M,DMPK,CDK4,PPIF,RNF26,TBK1,CSNK1A1L,PIAS1,PICK1,RNF10,MAPKAPK5,CCL2,MGAT5B,DUSP6,PIGA,CHRM3,DCUN1D3,TRIM35,G2E3,ASB11,ADPRH,PARP11,RNF41,ANKIB1,ZC4H2,DPH6,CDC23,MAP3K21,SPOPL,FBXL3,OARD1,LYPLA2,ROCK1,YWHAZ,PRKACB,ST3GAL5,VKORC1L1,CDK17,SETD4,CUL3,CDCA3,TRIM10,ZNRF1,STT3A,CAMK1,PIGY,AREL1,ASB8,RCE1,PPM1B,PPM1G,IL15,NSMCE3,METTL21A,PRRT1,CCAR1,PPM1K,RNF115,CLK1,VRK1,DYRK1A,GAL3ST1,PTPN22,USP13,TRIM37,ZDHHC24,CREBBP,UBE2F,MPDU1,MARCHF3,QPCTL,METAP1,PAK6,KLHL12,RNF39,SNRPD3,DCAF11,SRPK2,RING1,BAZ1B,TRIM22,CDK7,P4HA2,CSTA,USP14,EDEM1,SETD3,RNF126,COPS5,SUMO1,EEF2KMT,CTBP1,PRKCB,MARCHF5,RPS6KA4,CDK1,PELI3,OST4,UBE2A,DAD1,CTDSP2,WDR45,NAA50,CDK5R1,USP15,MED21,SOCS4,WWP2,KLHL7,SLC35A1,PRDX3,CDC20,DAPK1,CREB1,ANAPC4,FBXO11,COPS4,BRCA1,WWP1,IFIH1,EGR2,MTM1,PSEN1,TNKS2,PLPP6,TRIM26,RNF113A,UBE2I,SELENOO,RC3H2,VCPKMT,USP8,TNKS,TAB1,TRIM11,PRDX4,SOCS3,PPP1CB,COQ8B,LYPLAL1,ST3GAL1,PTPRZ1,CBFB,FKBP1B,NAA60,PIM2,STX1A,RAB6A,ABHD17A,ZDHHC8,FEM1A,KCTD11,DPAGT1,MAPK10,CAB39,RNF182,ROCK2,RAF1,NAA15,APPBP2,DDRGK1,MAP3K11,GALNT2,SENP8,TRIM6,PRKX,ETF1,FBXO31,TRAF2,TRAF1,ACVR1,AIPL1,STK38L,DDR1,RNF144B,PRKCA,FBXO3,UFM1,PSMD14,EDEM2,PPIH,POMT2,RABGGTB,ATG3,USP16,DCUN1D1,PGGT1B,UBE2E3,STRADB,TRIM23,RAG1,FBXW11,NDUFAB1,PTPRQ,TTLL10,FGFR1,TRIM27,FKBP10,FBXL7,CDK6,PTPN11,HUWE1,CCL11,ENC1,LCMT1,UBE2D3,PGAP4,IL21,EEF1AKMT3,ZNF451,GOLGA7B,RNF187,PRKCQ,STK24,COP1,UBR7,HECTD1,RNF20,B4GALT6,JOSD1,CCNA2,CSNK1A1,ST8SIA4,DESI1,IKBKB,GAPDH,CHCHD4,UBE2H,CUL2,EZH2,ITK,CEP41,FBXO22,EDEM3,DCAF16,UBE2G2,CDC7,UBE2V2,DPH3,UBE2V1,SDHAF2,ASB3,RPS27A,RNF128,PRMT5,MAPK4,RPN1,WDR77,PRKD3,NAA16,TTL,RNF103,EP300,NTAQ1,COPS7B,RNF208,CRTAP,CTNNB1,EIF2AK2,RIOK2,DESI2,ATG4C,WDSUB1,TRIM24,MARCHF4,UBE2N,STK26,SKP1,CDK12,UBE2M,CTDSP1,GALNT17,CAND1,JAK2,PTEN,MED31,CDKL2,FBXL19,B4GALT7,UGCG,GSK3A,RNF122,TRIM34,PAK5,TRAF7,PELI1,NEUROD2,GNMT,WSB1,RNF14,UBE3A,RNASEL,FGR,UBE2E2,BRAP,NIM1K,UBB,CSK,USP2,COPS7A,STAMBP,PI3,KBTBD13,JAK1,UBE2B,SMURF1,ANAPC2,KLHL24,DPH5,NEURL2,IFI27,BAP1,MED30,OTULIN,ANAPC13,UBL4A,CISH,ZDHHC4,STK38,FNTB,GPAA1,DUSP22,ATG16L1,NT5C2,ATG4A,SELENOK,ELOC,TRIM62,IRF2BP1,NAE1,NDP,FKTN,UBLCP1,TRAF6,CCNF,NAA11,ZDHHC16,TPST1,FAM20B,NEK2,TMEM59,RNF40,TRIB1,PML,IRF2BPL,BMPR1B,MGAT4A,P3H1,LIPT2,SPATA2,B3GNT2,FUT9,SUMO2,PPID,PPIL3,SRC,CDK20,MTMR2,EXT1,GXYLT2,RAB40AL,LEP,MGAT4B,SNRPB,TRIM21,CBLL1,RNF121,MED17,GALNT1,RNF146,DTL,BIRC5,MACROD1,METTL22,USP30,SENP5,TESK2,STK16,TRIM45,MAN1A2,C1GALT1C1,PIGK,TRIM3,SLC30A5,STYK1,NBN,MGAT1,NTRK2,B4GALT4,GOLGA7,BMPR1A,UBL5,GCNT3,FBXO7,NFE2L2,PRMT6,LYPLA1,UBASH3B,SPSB3,BMPR2 |
| 9.320e-07 | -13.89 | PPAN-P2RY11 (PPAN-P2RY11 readthrough) | protein interactions | 692312 | 142 | 67 | 19454 | 5460 |
APEX1,RPL19,RPL10,RPL13A,RPL35,RPL37A,PRKRA,FGFBP1,FAU,RPS3,ZNF330,H1-1,RC3H2,LMNB1,ZNF668,MYC,RPL7A,COIL,FTL,UTP23,DGCR8,NPM3,NOP53,STAU1,RPL4,RNF113A,ZNF574,RPLP0,MACROH2A2,GRM2,CDC42,RPS14,H1-5,SURF6,RPS10,LYAR,RAC2,SRP14,RPL8,SRSF1,KRR1,RPS2,NOL12,RPL10A,DDX23,H2AC4,GRSF1,PLEKHO1,RPL28,PTGES3,RPL17,KRAS,HMGN4,RPL23A,RPL3,RPS24,RPL31,PPAN,ILF2,RPL18,SART3,RBM34,MAK16,H1-3,RPL15,RAF1,RPSA |
| 9.451e-07 | -13.87 | FNDC3A (fibronectin type III domain containing 3A) | protein interactions | 22862 | 286 | 118 | 19454 | 5460 |
ACTB,TUBB,TENT5C,RMDN3,SEC61B,LMBR1L,RAN,DLST,HSP90AA1,CKB,LMNB1,THAP7,MCM4,KDSR,ACO2,LDHB,RAB11A,STX7,CHRNA7,PXMP2,AZGP1,HSCB,NSFL1C,EEF1G,GRPR,HSPA8,RAB5A,OR1M1,XRCC5,ANXA7,SEC62,OTULINL,ACTL6A,NUP35,HSP90AB1,CCAR2,SPTAN1,GJA1,SPINT2,FABP5,DDX1,HNRNPD,AHSA1,RHOG,FKBP4,LAMP2,HNRNPF,SLC25A5,CYP2C9,HSPD1,TMT1A,CCT8,RPN1,STIM1,PDHA1,RAB4A,PTRH2,BZW2,PPP2R1A,DNAJC25,ERLIN2,EEF2,FEN1,HSDL2,SUCLG2,SEC63,BCCIP,LDHA,PSMC5,RPS3,UQCRC2,CD1E,EIF4A3,ENO1,TNFRSF1B,OAT,CALU,EIF3G,NONO,TUFM,PGK1,RAB9A,DERL1,APMAP,P3H1,JUP,IDH2,HSP90B1,SSR1,CDC42,ST7,UBA52,TMPO,STX6,LMAN1,DNAJC1,CD151,HSD17B11,RAC2,SYNCRIP,PTPN1,ESYT1,LANCL2,LAMP3,GAPDH,GMPPA,FKBP8,RAB3B,IGF1R,IDH1,CTXN1,RAD23B,FURIN,MAGEA4,EEF1A1,CCDC47,CCT5,RPSA |
| 9.517e-07 | -13.86 | TMEM192 (transmembrane protein 192) | protein interactions | 201931 | 186 | 83 | 19454 | 5460 |
CTSD,NDUFB6,COX6B1,VAMP5,RPL7A,MBLAC2,GGH,LAMTOR1,RHOB,CD226,NTRK3,NAPA,SEC61A1,TNFRSF9,IL2RA,RAB14,SYNE4,LAMTOR3,NDFIP1,TAB1,ACP2,EFNA5,B4GAT1,SMAD5,FTH1,CNP,SDCBP,SDC2,STOM,SLC12A2,PPT1,HEXB,LEMD3,BOLA3,TSPAN15,SLC2A3,TMEM106B,MRPL34,RAB9A,SQSTM1,PRCP,CLEC12B,TSPAN5,TOMM20,LAMP2,H2AC14,RAB5C,SLC38A7,LAMTOR2,SEC61A2,LAMP3,NGDN,SLC2A1,SMAD3,SDC4,CD63,GYS1,LDLR,EIF2B5,SLC38A2,ERLIN1,CD28,RAMP3,NPC2,MAP1LC3B,TMEM59,SMAD1,TFRC,CTSA,TAB2,PLD3,CYB5B,STX8,SLC25A10,CD83,JAK1,MYO1B,ERO1A,ICAM3,B4GALT7,FLOT1,PAEP,CTSC |
| 9.520e-07 | -13.86 | USE1 (unconventional SNARE in the ER 1) | protein interactions | 55850 | 134 | 64 | 19454 | 5460 |
TRIM27,SEC61B,VAMP3,LMBR1L,VPS72,APEX1,PSMD4,BTF3,CREB3,SCN3B,VAMP5,MFSD14B,SCFD1,EPHA2,NAPA,DERL1,JAGN1,SNAPC1,PXMP2,STX7,GOSR1,YKT6,NAPG,OTULINL,CDC42,SEC62,ST7,TOMM22,GOSR2,BET1,SEC22B,LMNA,SSR1,STX17,HSD17B11,RPLP2,RAC2,STX5,TMPO,NUP35,VTI1B,DNAJC1,KXD1,STX1A,VPS4A,SKIC8,BSCL2,STX18,EMC2,STX8,TYW5,RINT1,TMT1A,FKBP8,POLDIP3,HS2ST1,KRAS,DNAJC25,PPP2R1A,STX12,TAF2,STIM1,RPN1,RAB4A |
| 9.533e-07 | -13.86 | EXOC5 (exocyst complex component 5) | protein interactions | 10640 | 126 | 61 | 19454 | 5460 |
RPA2,HECTD1,TXNL4A,FAM234A,ATG16L1,MTX2,NPY2R,NPTN,KRT222,STX7,RPA3,CD40,DVL2,YWHAZ,EXOC8,ICA1,DSN1,CREBBP,CUL3,PYCARD,GPR17,OPRM1,RAB11A,EXOC5,DNAJC5,ATP5F1B,RALA,RAB14,CHCHD3,ESR2,SCN2B,LURAP1,ENO2,SEC61B,PTEN,CA14,EXOC3,SCHIP1,STIM1,IFT57,RAB4A,HGS,IL1R2,TNPO2,ZNF609,SEMA4C,STX11,OAS1,EFNB1,ERP29,EXOC2,KXD1,USP2,ACTR3B,EXOC1,ADCK1,ARF6,THOC1,BRMS1L,CDC5L,CD274 |
| 9.533e-07 | -13.86 | GET3 (guided entry of tail-anchored proteins factor 3, ATPase) | protein interactions | 439 | 126 | 61 | 19454 | 5460 |
TUBB,PSMB6,ESR2,POLR3B,SEC61A1,SEC61B,SGTA,FAS,PSMD14,NRP1,SCFD1,PSMB2,PSMA4,TTR,NSFL1C,BAP1,RPA3,PML,HSPA8,YAF2,VAPB,RARS1,SEC22B,PSMB3,PGRMC1,SPPL3,EGLN3,PSMB5,CAMLG,PSMB1,STX5,NUDT9,SPP1,SKIC8,AGR2,CDK12,DNAJB2,COPS5,KRAS,HUWE1,PSMA2,GTF3C3,PFDN1,AHCYL1,FAF1,SMIM19,APLN,LDLRAD4,RUVBL2,PDIA6,TUBB4B,GPX7,VAMP2,DISC1,CREB3L4,RNF126,TAF2,CYB5B,UBL4A,MAGEB10,HILPDA |
| 9.533e-07 | -13.86 | HTR2C (5-hydroxytryptamine receptor 2C) | protein interactions | 3358 | 126 | 61 | 19454 | 5460 |
SLC39A10,GJA1,ACTA2,ARL10,CNIH1,CAV1,RMND1,CAND1,DERL2,TMBIM6,DCAF11,FITM2,FAM241B,SLC35G2,ERG28,TMEM147,RINT1,LPCAT3,SLC29A1,TNPO2,ATP5PB,CRELD1,GNAQ,TMEM94,CBX3,SLC35F1,CAMK1,PTRH2,TRMT11,LRRC1,RETREG3,SERINC1,GPR89A,PLP1,DLG4,GPR37,ACP2,SEC63,ATP6AP2,TNPO3,LRRC8A,ATP5F1B,LGALS3,HMOX2,SNTA1,TAPBP,SLC35F2,RTN4,SLC39A9,LIN7C,PPM1G,RETREG2,NT5C3A,CERS6,CERS2,SYNGR2,SLC19A2,LMBRD2,GHITM,EIF2B3,GOLGA5 |
| 9.578e-07 | -13.86 | cell population proliferation | biological process | GO:0008283 | 726 | 273 | 18204 | 5365 |
NKX3-1,POLDIP2,NOG,EAF2,HRAS,STK11,FGF7,CLU,FAM83A,GNB1,EPHA2,SAV1,BCL6,LBX1,CD40,UBE2L3,CDKN2C,GPAM,CCN3,WNT2,GLUL,SERPINB1,MSX1,PRKX,SELENOK,STC1,LMBR1L,TNF,RAF1,GINS4,SMAD3,CX3CL1,RBPJ,IL10,FOXC2,XRCC5,TBK1,CD38,CD2AP,GJA1,DDR1,CLEC12B,MARCKSL1,NDP,ILK,KCNJ8,FGF13,RB1,IGF2BP1,IL2RA,NPPC,DISC1,FOS,CDK9,SPHK2,SDR16C5,CDKN1A,PHB2,CKS1B,PIK3CG,ALKBH3,DDIT3,CER1,SQSTM1,CD40LG,TLR4,NKAP,PRDX1,FGFR1,EXT1,PTGES3,NDE1,IL18,RAC2,PRDX2,SRC,SIX5,GNG2,AZI2,LEPR,LGR4,TMEM14B,ETV6,PAFAH1B1,IFT52,DIPK2A,NDUFS2,STK4,IDO1,TP53,RACGAP1,LIPA,FZD4,TRNP1,NBN,BTG2,NR2E1,HELLS,CDKN1B,NAA35,PRKCQ,ADGRG1,FZD6,BMPR2,YTHDF2,IL23A,VEGFA,CD248,NCSTN,NF2,IL7,IL15,TICAM1,IL34,EGR1,BMPR1A,MECP2,NDC80,GAPT,RRM1,SEMA5A,IFNA13,CDH13,STAT6,TNFSF18,PROX1,HAND2,SMAD4,USP13,IRF2,COL3A1,WNT7A,MIOS,FABP7,AKT1,BTBD10,CTNNB1,TXNRD1,FGF10,GSTP1,NPR2,RERE,BAK1,GPX1,CCND3,IRF6,PAK1IP1,HMX2,KRAS,NOTCH2,IGF1,DIO3,WDR77,ABCB1,TGFB2,OVOL1,CCND1,SNAI2,TGFBR2,IL2,EFNB1,RRN3,AR,TRIM24,DLG1,MSN,PROK1,CTNNA1,FZD3,SART3,GNAI2,NDFIP1,KIT,SOX9,FOSL2,CDK5RAP3,PPP1R8,MAP2K1,BAD,CD34,RAP1B,IGFBP4,SMAD1,OR51E2,BCL2L1,LIMS2,CD151,STAT1,FGF1,B4GALT1,PELO,CAV2,ING5,EIF2S2,CSF2,MTA3,MAB21L1,HEY2,PELI1,PAK5,VEGFC,EMX2,STK3,SASH3,JUNB,HNF1B,COPS2,FOXP3,HSPD1,OSR2,LILRB1,CDK1,ERRFI1,LNX2,BAX,IFT172,FLCN,ID4,NDST1,IL6,ASPM,IFNA10,BGLAP,BTG1,NUPR1,PTGES,YPEL5,ACVR1C,CCL5,FGR,KPNA1,IL12B,MMP14,DSN1,ENPEP,SFN,IGFBP3,POC1B,FAM83B,IFNA2,FGFBP1,CD9,PSEN1,CKS2,ECD,IFNK,THAP1,IL20RB,PSMB10,RUNX1,EMP2,IFT57,SMAD2,ZBTB16,ALKBH5,NAA60,FKBP1B,BAP1,ODC1,BABAM1,CD28,OTUD6B,MEF2C,HHIP,NCAPG2,SLC20A1,IFNB1,CAV1,PAX6,RC3H2,EDNRA,WNT10B,VSTM4 |
| 9.591e-07 | -13.86 | inflammatory response | biological process | GO:0006954 | 559 | 217 | 18204 | 5365 |
TLR3,MACIR,CXCL9,CCL5,MIR223,PYDC2,PLA2G4B,NUPR1,PTGER2,CCL17,TRAF3IP2,IL6,NDST1,SERPINA1,SCG2,FOXP3,RPS6KA4,MIF,CCL3,IFNGR1,MIR130B,TXNIP,TSPAN18,TYROBP,CD36,HP,TACR1,MYD88,IL4,TLR9,TNFRSF1B,IL20RB,NLRP9,IFNA2,PTN,CXCL3,PSEN1,IL1A,MAP2K3,DPEP1,NOTCH2,CERS6,POLB,PLD3,CCL24,LIAS,CXCL11,TNFAIP3,AKT1,DHX9,IL1B,CXCR6,NFKBIB,CXCL1,CCL20,FKRP,NCR3,CCR6,AGR2,FOLR2,TLR6,CCR7,B4GALT1,TIRAP,IL5,SMAD1,NLRP6,JAK2,TLR7,FCGR1A,FOSL2,LACC1,CCR1,HDAC5,ACER3,CD14,CCR5,OLR1,KIT,IL22,DHRS7B,MIR20A,ODAM,CCL21,TOLLIP,HNRNPA0,PRCP,MIR221,PLAA,IDO1,TAB2,IFNG,TAC1,CD47,IL17F,CXCL8,FADS2,IL13,TNFAIP6,CLEC7A,LARGE1,ADORA3,ADORA1,CHST1,MSMP,EXT1,PNMA1,PRDX2,UGT1A1,IL18,PIK3CG,TLR4,CD40LG,LXN,CCL11,CCL8,MIR181C,IKBKB,IL34,SERPINA3,TLR1,TICAM1,EPO,NFE2L2,ATAT1,TIMP1,LYZ,IL23A,SEMA7A,PRKCQ,AFAP1L2,CCL1,PLGRKT,SETD4,CUL3,CDO1,F11R,CTNNBIP1,PTGER4,CXCL13,TLR8,IFI16,LIPA,CX3CL1,IL10,XCL1,PTGFR,RBPJ,CCR3,TNF,TMIGD3,TFRC,LY96,TUSC2,CRHBP,FCGR2A,CX3CR1,BCL6,WDR83,EPHA2,CCL23,CD40,H2BC1,SYK,CLU,HMGB1,NLRP1,MBL2,CCR4,AGER,PYCARD,IL1RAP,FCGR2B,S100A8,CXCR4,BMPR1B,IL2RA,CXCL10,FOS,CCL2,CHI3L1,CCL4L1,MRGPRX1,PLP1,ALOX5AP,NLRP2,CASP4,PTGER1,CCL18,NKIRAS2,NFKB1,KCNJ8,TLR2,RARRES2,CCL25,NLRP3,ACVR1,TLR10,NDP,TICAM2,CD2AP,CHST2,SNAP23,CXCR3,PLSCR1,TBK1,BPGM,NINJ1,ADGRE2,POMT2,TLR5,CCL19,AIF1,ABCF1,VPS54,F2,CCR2 |
| 9.679e-07 | -13.85 | Cross-presentation of soluble exogenous antigens (endosomes) | REACTOME pathways | R-HSA-1236978 | 51 | 33 | 10285 | 3229 |
PSMB11,PSMC5,PSMA5,PSMB10,PSMA4,PSMB3,PSMA6,PSMD1,PSMB2,PSMA2,PSMB6,PSMB1,PSMD3,PSMB7,PSMD12,PSMC4,PSMC1,PSMB5,PSMA3,FCGR1A,PSMA1,PSMC3,PSMD14,PSMD4,MRC1,PSMD6,PSME1,PSMB4,PSME2,PSMD10,PSMD7,PSMB9,SEM1 |
| 9.713e-07 | -13.84 | Cellular responses to stress | REACTOME pathways | R-HSA-2262752 | 451 | 189 | 10285 | 3229 |
GPX2,NUP50,PSMB1,CCAR2,DNAJB6,CDC16,PSMC4,CDK4,IL6,SOD2,PSMB11,PSMA4,EPO,RHEB,RB1CC1,H2BC11,TXNRD2,HSPA14,PSMA2,PSMB6,PSME1,CUL2,H2BC12,MAP2K3,PSMD14,RB1,UBB,RING1,ATG101,ATG9A,NUP37,GPX1,PSMD12,ANAPC16,H2AJ,H2AX,EED,CDK6,RRAGA,ANAPC15,EGLN3,HSBP1,RPA3,CHMP4C,NUP153,SP1,PSMB9,DYNLL1,H2AC14,RRAGB,H2BC9,CCS,PRDX1,MAP1LC3A,HSP90AB1,GPX6,ID1,H1-1,FKBP4,EGLN2,NFKB1,ATG16L1,TXNRD1,H2BC14,GPX5,IL1A,PSMD10,GPX3,SOD1,ASF1A,MOV10,H1-3,TNRC6C,LAMTOR3,MAP2K6,PRKAG1,HIRA,PSMC1,CREBBP,WDR45,ST13,HMGA1,PRDX6,HSP90AA1,PSMD1,PSMB2,NUP42,HDAC6,CDC23,HIKESHI,H2AC4,NBN,NUP62,PSMA1,PSMD4,EZH2,NUDT2,H3C1,GABARAP,GSTP1,PSMB7,PSMD3,CDKN1B,CDKN2D,FOS,PSMB5,PSMA3,PSMB10,DNAJC2,TXN,PSMC5,JUN,H2BC17,PRDX2,RPA2,AGO1,BAG2,PSMD7,ELOC,CXCL8,HSPA8,CDC26,H2AZ2,ATG3,MAPKAPK3,CDKN1A,H2AC7,LAMTOR1,MAPK10,H2AZ1,EEF1A1,NUP107,RBBP4,BAG3,PTGES3,MAPKAPK5,ANAPC2,PSMD6,PSME2,UBE2D1,IFNB1,CHMP2B,H1-5,FZR1,GABARAPL1,CDKN2C,SOD3,H2BC1,CHMP2A,CCNA2,TFDP2,NUP35,MAP1LC3B,TNIK,RBBP7,MDM2,PSMA5,PSMB3,GPX7,ATG4A,DNAJC7,EP300,ERO1A,ATG7,UBA52,CAMK2G,H2AB1,PHC1,GABARAPL2,HSPA13,LAMTOR2,PSMA6,BECN1,PSMB4,UBN1,ATG4C,ANAPC4,VEGFA,PRKAB1,SEM1,H2AC6,UBE2D3,PSMC3,TP53,ANAPC11,LMNB1,RPS27A,HSPA5,PRDX3 |
| 9.779e-07 | -13.84 | nuclear lumen | cellular component | GO:0031981 | 4888 | 1552 | 19108 | 5553 |
GTF2H5,HSP90AB1,ARL14EP,FUBP3,TLE1,CAND1,TREML1,XRCC5,SDCBP,DCAF16,FOSL2,SRSF10,E4F1,EZH2,HR,PSMB2,DEK,SMU1,MED22,SLC25A10,RTCB,RGCC,ALKBH5,H2BC9,EIF2D,HSCB,RBPJ,TFE3,POLR1B,UQCC3,TULP3,RPGRIP1L,MDM2,TIMM13,RPL23,NR0B1,GCFC2,UBE2W,AURKAIP1,WDR82,CBX7,LMO2,CDC20,PRIM2,CCNA2,EID2B,NABP1,CRTC2,STAT1,SIX5,RGS10,ETV6,DCLRE1C,DCUN1D1,POP5,NKRF,SMC4,RACGAP1,MED31,UPF3B,TRIM34,THAP7,MYC,SKP1,COMMD5,ZBED1,MACROH2A1,CGAS,PRMT6,UQCC2,SOX3,MAEA,KPNA1,STXBP1,ZHX1,NOP9,PSMA4,OSBP,PHF12,MORC2,RPL13A,PRPF18,P4HA2,PIR,CDK6,TAX1BP3,ACTB,ASF1A,ZNF24,WDR20,AQP3,IRF9,PPP1R8,ZNF207,GTF2E1,DNAJC8,NRBF2,TAF1D,HNRNPDL,CCDC174,HCFC2,TUBG1,RMI1,MEF2A,UBE2S,GTF2IRD1,SUB1,FOXD3,GOSR2,DNAJC7,NAA11,RMI2,TFPT,IFI16,TP53INP2,GTF2A1,RPRD1B,PAX9,RERE,ZBTB45,HNMT,NOL12,H1-1,FEM1C,GATAD1,DCTN3,FYTTD1,HDAC11,ZNF436,ZBTB33,NR2F6,RBM7,PPP4C,ATXN1L,CASC3,ADD1,CPEB1,CNDP2,ARL4D,SLU7,CD2BP2,ISG20L2,RNF113A,CD2,ADH1A,FBXW7,DDX39B,CIART,CAMK2G,GCHFR,SERTAD2,TSEN34,PHB1,DNAJC2,GPC1,PRKD3,UBE2D1,GFI1,CMTR1,MED10,RPP25,H1-5,RBBP9,BHLHE40,PPARG,PSMC1,RPAIN,ABCF1,GGPS1,FAHD1,ALKBH4,TESC,PCBD1,MRTO4,RPRD1A,SMURF1,SMAP2,CD274,SPTBN1,PPIL4,PRCC,DLST,RBM5,PSMD14,RPF1,DYRK1A,UBL4A,H2AZ1,OARD1,TADA3,PAGR1,AIP,MYRF,FBXL4,KPNA6,RPS7,PLA2G15,ATP6V1D,ELK4,SNRPA,UBE2V2,KMT5B,MCM3,HSPB8,LMNB1,TXNL4A,CNOT7,HNRNPA0,SUPT5H,BANF1,TRA2B,BCCIP,LDB1,RCHY1,ENY2,RAN,CBX5,POLR2D,CREB3,KLF9,POLR2I,C1D,APOBEC3A,CCND1,CCDC22,SETD3,MITF,SF3B4,ZNF175,XPOT,PMM2,CFL2,DNAJB6,COX10,CAPG,H2AC6,COP1,PRPF31,RNF7,DNTTIP1,MYCT1,CNOT2,PSMC4,STAP1,BUD23,CSTB,HNRNPL,RPS6KA4,ABITRAM,UBE2N,SGMS2,SERPINB10,SUMO1,POMT2,SF3B1,ZNF326,EP300,CHST2,MCOLN1,MAF1,MGMT,PLAGL1,CDK9,NAB2,ACACA,TESK2,UHMK1,ADK,FCF1,INTS10,NXT2,PSKH1,PEG10,RBM18,NUDT9,RPS17,RPS5,SYCE3,PDHB,HBP1,HRAS,PRDM4,PPM1B,EMG1,HOXB1,HILPDA,NUP153,EXTL2,RBM22,ZBTB39,NDUFS2,ZNF473,PTEN,CLPX,TAB2,PPP1R12A,PGR,ATF1,NFYA,LSM5,BTG1,ABHD17A,PAPOLA,RPS27A,TAF10,CCT8,DPY30,SMAD1,PHF1,PYM1,MIOS,TGFB1I1,ANAPC11,CWC15,LDOC1,PTPN11,CHAMP1,PSMB6,USP15,SPOP,UBB,ISG20,TSNAX,GTF3C4,EID2,DNAJB4,NDUFB5,METTL14,HDAC5,RERG,VTA1,RPL4,ZNF622,ZMYM2,TOP1,RAD23B,SHOC2,AFTPH,GTF2H2,HNRNPD,RPS2,PPME1,BRD9,ID4,HSP90AA1,CTNNBL1,RPS11,FOXN2,MSX2,RFC4,PTPN4,GON7,AKAP8L,AGER,CDKN2AIP,MYO6,EYA3,CCAR1,CDC26,POLE4,ING2,MXD1,SYVN1,PROX1,RUVBL2,SIAH2,H2BC11,CCR2,ISG15,OLR1,CHMP1B,ZBTB16,RLIM,ELOC,MAP2K3,BAP1,MED17,HFE,SNRPE,SLC39A7,CEP85,EHBP1,MRPS26,TWIST2,PRPF19,CUL2,TRIM22,EDF1,RFC2,INO80C,NXT1,RADX,RSAD2,CDC23,PRDX3,DRG1,TNRC6C,NONO,PSMA2,DUSP26,SNRPA1,GIMAP2,POLR3B,IPO8,MAD2L2,PSMD1,PSMD4,CPSF2,TRMT61A,RPS4X,HYPK,CDKL2,TMEM179B,RBM3,CDKN2D,OLA1,NFE2L2,ZNF451,EEF1A1,RUVBL1,CHTOP,NEDD8,PHF13,EXOSC3,CEBPG,GTF2F1,MDC1,HOXB8,ZNF22,FRMD8,KRR1,TOPBP1,SPRN,FOS,HEXIM1,RFX5,THOC6,ZNF687,SMAD9,FERMT2,CBX3,POLD4,PML,TMUB1,PSMB4,LRIF1,RXRG,CBR3,SP2,NFKBIL1,FTSJ3,H2BC17,HADH,TMA16,SETD5,PHF23,NCAPG2,POLR2B,GTF3C3,RPL3,SAP30BP,IRF3,ARPC2,AATF,AMT,PWP2,HNRNPAB,MAPK10,PHB2,PPWD1,NOVA1,HIRA,PSMC3,TERC,KANSL3,SMAD2,SCNM1,UBE2L3,DYRK1B,NGRN,NEK7,MPHOSPH6,RAB5A,TIMM17A,ELOF1,TNFAIP8,TRIM27,HNF1B,RETREG1,CDC7,PPP1CC,JUNB,NAA15,CACNB4,DLX1,SUPT7L,MRPL36,MIF,CCAR2,RBM42,JADE1,LIPA,UQCRC2,NEK2,JAML,NAA35,MBD3,EGLN3,APOBEC3H,RPSA,PPP1R26,UTP23,PSMB1,DHX38,MYBL2,AIPL1,LSM4,BAG3,PPARA,YPEL4,MED11,RIOK2,ZC3H11A,THAP1,FAM193B,SRSF8,MRPS18B,FGF1,PSME2,TRAF7,RPL27,SRSF7,ILF2,RRP7A,TAPT1,IRF2BP1,TAF5L,ADRM1,CREB1,USP39,ZCCHC7,EIF1AD,DTL,IK,EIF2AK2,DXO,PQBP1,RAPGEF5,PAFAH1B2,CCNB1,NUFIP2,FBXO3,FOXP1,KIN,SKAP2,PYCARD,TRA2A,MEF2C,BOLA3,FAM222B,BNIP3L,FHIT,ARHGAP15,POLR1H,SMUG1,RPS26,OSGEP,POLR1D,ELP3,MBD5,DHX9,PIP5K1A,PYDC2,PPIH,UBE2I,ZBTB38,PHC1,BTBD10,TCF21,RBBP7,E2F6,NUP50,PDHA1,BARX2,DDRGK1,EIF4E,TAF7,PRMT5,CLP1,KLF4,CDK5R1,RPS15,HMGB1,APBB3,ZC3H14,CTBP1,NDUFS3,TRIM6,CCDC106,TENT5C,NR1I3,ZNF692,GLE1,RPA3,SKIC8,ANP32A,MAD2L1BP,TXNRD1,CTNNB1,RNF187,DUSP10,SNAP23,CXXC1,CCNH,NCBP2,LDB2,IRF7,UTP25,MCL1,SRSF4,IQSEC1,FBXO7,DENND2D,SRPK2,TRIP4,POLR2F,E2F4,PDE9A,LSM2,APEX2,CPSF4,CTDSP2,LIMD2,DBR1,SPC24,EGR1,SNAPC2,KLHL7,SUMO2,SLA2,TP53,MED13L,RPL23A,HLF,CTSC,HMGA1,COPS7A,TRIM8,RPS20,PTPN5,GEMIN8,H3C1,CTDSPL2,MORC4,NR4A2,CENPM,ASCC1,TAF2,CMKLR2,BECN1,MSH6,MED30,MXI1,MAGEC2,MED4,SNRPN,MRPL40,TNFSF13,KRT8,RPS9,FAAP100,CACYBP,MED29,GLO1,RBMX2,NICN1,ZMYND11,RNF8,FOXC2,STK16,SOD1,INPP4A,FOXP3,IMP4,PRPF4,NUP62,RPL35,IRF1,PPIG,SGF29,APOBEC3B,RPA2,RNF14,MTX2,MED23,PSPC1,ZBTB26,SUFU,FAM76B,RING1,SPMIP6,TCOF1,RPS14,ZBTB18,SNRPD2,UBE2D3,MED27,MCMBP,API5,WBP2,FBXO11,THAP2,TBK1,ODAM,RPS29,RNF126,GIT2,IFI35,RFXANK,CDK1,TRIM24,PSMD6,FZR1,MTAP,SNAPC3,EGR2,ABHD16B,TFDP2,NAA50,STAT5A,MACROD1,CCND3,EIF3E,DKC1,DCP2,CXXC5,GJC1,CREB3L4,HDHD3,SIRT7,EIF4A3,PSMD10,THOC1,CTSK,KLF3,ZNF609,YIPF5,AKR1B1,MNAT1,STAC3,XPO5,CDCA7L,AP5S1,RIMOC1,LSM8,DRG2,POLR3H,ANAPC15,RALYL,TCEA1,THOC3,CD63,ATPAF2,MPIG6B,CGRRF1,PPM1D,DPPA2,SMARCE1,SAP30,CLIC4,KLC2,CEP19,ADRA1A,ERCC3,ZBTB6,MPG,CCDC86,ZMAT2,NMRAL1,NMI,RSRC1,DDX5,NFE2,NUF2,OLFM2,CFDP1,PSMB3,SUPT4H1,TRMT6,CFL1,VPS54,SDHAF1,UBA52,TASL,SMNDC1,SMCHD1,BIRC5,POLR2C,SF3B5,RPS3,DCTPP1,DSN1,SNIP1,MCM4,IRF4,DR1,REXO2,VRK1,HEY2,RPL7A,RBFOX2,GRAP2,MECP2,POU1F1,HCFC1R1,DNTT,TIMMDC1,SPR,WRAP53,HNRNPA2B1,MRPS9,EXOSC1,POLA2,GJA1,RBM17,CD2AP,H2AX,AR,SPATS2L,EWSR1,UGDH,SENP5,EGLN2,GID8,DUSP3,PARP11,MSX1,CPNE1,RBBP4,POLR3GL,FEN1,NUCKS1,AGAP2,SMYD3,KHDC4,PAK5,GRSF1,HSPB6,PLSCR1,MAGOH,CDK5,TEX12,RBM34,RPL7L1,NR2E1,MCPH1,TIA1,CDK5RAP3,UFD1,GTF2E2,ZMAT5,WBP11,YAF2,WEE2,RP2,UBE2E3,KIT,RPP21,CTNNBIP1,TP53TG5,SNAI2,SERPINB9,RPF2,MRM2,TOP2B,RBM12,CDK20,IGF2BP1,CKS1B,S100PBP,TXNRD3,NRDE2,EAF2,WDR55,NUP42,AKT2,KIF2A,RNF34,ANAPC16,NFE2L1,SETD9,CDC5L,NOB1,PNO1,S100B,MACROH2A2,PSEN1,KCTD10,NOL7,SF3A1,PPP3CA,PSMA5,CCNY,SNRNP40,ENC1,SMDT1,SDHB,LSM6,ZNF655,STK4,ZNF174,RFXAP,FAU,CEBPE,RNF20,UBN1,ACTL6A,BAALC,PRKAB1,ARMC8,UBE2B,CBFB,FANCG,ECD,MIDEAS,CGGBP1,USP13,PIP4K2C,POLR3F,NUP107,DNLZ,HEXIM2,SNAPC5,DDX39A,USP3,NT5C3A,PSMA3,MFAP3L,CSNK1E,SUGP1,IL2RG,CITED1,RAD1,NOSIP,SAP18,ZBTB25,H2BC12,CCDC92,IVNS1ABP,RPS16,NUPR1,DHX16,PCGF3,EZH1,TRAF2,HINFP,MARS1,GTF2A2,CHRAC1,HNRNPF,AGPAT5,METTL21A,ANAPC2,ZNF322,ANAPC4,SIN3A,GNAI3,LMNA,COPS7B,KDM1A,DMTF1,TNFAIP8L3,POLB,FAM118B,RARS1,DFFA,NTMT1,SATB1,MTA2,SUV39H1,HECTD1,NFKBIA,RPAP2,HP1BP3,ANP32B,RPS24,CASK,TRIM5,PSMB7,CDK2AP2,SLC35F6,CSTF2T,SMAD5,ORC6,WDR77,RPL27A,ALYREF,PPID,EXOSC4,CD1E,TRIM45,TCEAL1,RPS12,ARL4A,ID1,FBXL3,CREBBP,CENPL,TRIM37,MRPL10,PRM1,SNRPD3,BRAP,ARFGEF1,DAPK3,POLL,VIRMA,CRADD,PRKCB,CRKL,PFKFB2,STAT6,HNRNPK,STN1,STX12,INTS12,SRSF1,RBBP8,LRWD1,XPO1,LYPLA1,NKAP,PSMD12,FOXA3,PSMD7,PRR13,MAD2L1,KDM4B,ARGLU1,XBP1,PPP5C,ABHD14B,JAK2,NSA2,WDR12,LCMT1,NDC80,SRC,EXOSC8,DDX23,STAT2,SEC13,METTL22,RPS10,PAAF1,HDAC3,GMNN,RCL1,RFC5,TRIM68,PPM1G,PHF21A,SURF6,AKIP1,PNMA2,ZBTB14,SQSTM1,MYG1,YWHAZ,NFYB,BMPR2,DCK,SMARCA5,IL15,GRAP,EEF1AKMT3,PAK6,POGK,BCL9,GTF2B,PRKX,TAF9,PLPPR1,TFCP2,STX6,NDUFB4,CDKN1A,RRAGA,FKRP,S100A10,CRABP2,MAGED2,MPHOSPH10,HOXC4,NBN,MEAF6,RORB,AGO1,CSTA,CENPW,MORF4L1,BRIX1,PIH1D1,MTDH,ELK3,RPS23,TOLLIP,RPL18,GADD45A,CREBZF,BPNT2,LANCL2,SAMHD1,MATR3,CHMP1A,CTDSP1,ZNF593,NUDT16,DROSHA,SOX2,CMAS,DCUN1D3,NIBAN2,PCGF6,PIWIL4,PRKCA,NSMCE3,ZCCHC17,BRCA1,ABHD5,ZCRB1,SETD7,SPRY1,ZCCHC9,DAG1,PLEKHA8,VPS72,COPS2,TNIK,NDN,SIVA1,STK24,DCAF5,XAF1,ATP6V1A,LIG3,H1-10,AKT1,CDK8,NAB1,ZNF397,SNRNP70,UBE2V1,GABPA,PPP1R10,RPL12,DNAJB9,PNMA3,POLE3,NCOA5,PSMC5,CMPK1,COPE,TERT,CDC73,FAM20C,BUB3,NKX3-1,ALKBH2,OGG1,TSPAN5,DMAP1,GLRX2,LSM10,HIKESHI,NLE1,TTC4,HNRNPA1,PCNA,SLC8A1,RSL24D1,SNRPG,THOC2,AKAP17A,DYRK2,SLC35A2,PHAX,GRPEL1,EPOP,RPS13,DUSP6,LGALS3,INO80E,SLX1A,BCL6,RB1,BRMS1L,VMP1,SAP30L,PAK1IP1,TRIM11,CDK7,TCEAL7,DHX15,STUB1,TMEM70,OPRK1,THRAP3,PARM1,WTAP,SRI,LUC7L3,SLC7A14,PIAS1,DCAF11,MAK16,UTP15,TCIM,DDX1,SRSF2,APTX,LARP4B,MCM8,EID1,ESR2,COPS5,RPP14,INPPL1,PSRC1,SUMO3,CETN3,SSU72,JUN,TENT4A,LORICRIN,ATF3,RAD21,RBM27,CETN2,POP7,COMMD8,IRF8,SEC14L1,ZBTB42,SSRP1,RPL26,TNKS,CRYAB,COX4I1,CENPP,TFIP11,MFAP1,ELK1,PLCB1,NOC4L,RASL10A,ZBTB2,FABP5,PCLAF,RPL8,GNAI2,CFAP20,MCM6,HERC4,RBIS,IRF2,GABPB1,COMMD9,RNF208,PPIL3,SNRPD1,TRMT10B,ZNF330,MAGOHB,BAHD1,SF3B6,SNX20,FKBP4,GINS4,TOPORS,KLK6,LYPLA2,SRSF12,PRKAG1,PRMT2,MAP3K14,PARP2,ZBED4,DCAF4,BAZ1B,SHMT1,UPRT,PPP1CB,RRN3,PRRC2A,SHPRH,CHCHD1,GEMIN7,CDKN1B,G2E3,MEF2B,NDUFAB1,EEF1E1,HINT1,CIRBP,UBLCP1,SYNCRIP,ORC5,ZNF501,CBLL1,PRELID1,LSM3,PTHLH,MRFAP1,PSME1,SNRNP48,SUPT3H,NAIF1,STAMBP,VDR,LLPH,RPL19,SNAPC1,ZHX3,COPS4,MTA3,TRMT112,IER2,CPSF1,GINS3,NUP35,KPNA2,PHF7,FAM107A,MZT2B,MED21,DPEP1,TRIM21,NR1I2,MTG1,ADH1B,HDAC6,TCEA2,TP53INP1,DPH3,DVL2,MINDY3,RNF40,IP6K1,ANKRD10,MSL2,SP4,DEDD,CDK12,IMP3,HSBP1,GTF2F2,SHOC1,TADA1,NLRP1,SDHAF2,MLLT11,PCSK2,UBP1,FAM20B,SMN1,POMP,APEX1,PSMD3,TAB1,METTL18,RIT2,SMAD3,BUD31,MTF1,SNRPB2,RTRAF,RSPH1,SPATA2,PCGF2,EMX1,PSMA1,CSNK1A1,NOP53,UBE2M,MAX,SPRED1,NOTCH2,ING5,RASL11A,LYAR,SMARCB1,RFC3,PPAN,TSPAN15,ACADS,BABAM1,MKLN1,ATF4,APPBP2,CUL3,CSE1L,FAS,NR1H2,ELF1,PIP4P1,GTF2H4,SLC30A5,NF2,FAF1,OPTN,SMARCD3,PELP1,WDR5B,WDR3,CPT2,ARL2BP,MAPK4,CLIC2,HNRNPC,NFKB1,USP2,TGIF2,HSPA8,KLF1,FEM1B,CSNK2B,PSMB9,SPHK2,CSTF3,NPM3,POLD2,SNRNP27,DUSP18,POLDIP3,CDK4,OAT,NHP2,ARPP19,DDX42,NEO1,CAVIN2,PSMB5,ZMYM3,PRKRA,H2BC14,ZNHIT1,SOX9,MAP2K6,HNRNPH2,BATF,NUP37,SLC13A5,DDX50,ALKBH3,USP16,TDP1,UTP6,RPS28,BRMS1,FBXO32,KLF12,H2BC1,RDM1,TSG101,OAZ3,SNRPB,PPIB,HUWE1,CDC40,NOP16,MED9,NACC2,POU5F1,THUMPD1,FBXO25,SMAD4,UCHL3,CFAP68,PNMA1,PRKACB,CIPC,RNF146,UNC45A,MRPL52,NHEJ1,STK11,OIP5,LITAF,CDC16,POLR2G,GTF2I,NOP58,HPGDS,PTGES3,SART3,ABCG2,MAPKAPK3,VEZT,TXN,MAPKAPK5,MAP1S,ST6GALNAC3,ZRANB2,ZBTB17,CSNK2A1,UBL5,PSMA6,DDX46,FAM50B,MLH3,ZMAT3,RNASEL,UAP1,EED,TSEN54,RUNX1,NGDN,UBE2A,ACTL6B,PSMB10,IRF2BPL,TAF11,SH3GLB2,RAG1,SRP54,NOL4,RPL7,RBM15B,COIL,RGS2,PAXX,MRPL23,DGCR8,PAX6,PEX3,HNRNPH3,PEA15,OAS1,POLR2L,NDUFB6,SURF2,TSN,ZGLP1,SP1,LPXN,SPIN3,RANGRF,RIOX2,BACH1,KDM2A,MAFG |
| 9.824e-07 | -13.83 | GFM2 (GTP dependent ribosome recycling factor mitochondrial 2) | protein interactions | 84340 | 175 | 79 | 19454 | 5460 |
MRPS9,YBEY,FAHD1,MRPL50,NDUFS8,DBT,ATP5PD,MALSU1,MRPL24,MRPS23,GRSF1,STOML2,MRPS35,MRPL9,NDUFV2,TRA2A,LCN8,SSX2IP,MRPS26,MRPL52,ATP5PF,MRPS18B,HINT2,KRAS,MRPS33,ETFA,KGD4,ATP5F1D,MRPS17,RPL17,ATP5PB,NDUFA2,ETFB,TP53,MRPL47,PPIF,BCS1L,NDUFS6,NDUFS3,PDHA1,NDUFA12,MRPL49,TACO1,MRPL53,DLST,MRPS28,TRIM27,MRPL13,ATP5F1B,NMI,NDUFAF4,IFI35,NDUFAF2,PYCR1,PYCR2,TUFM,MRPS16,MRPS25,FAM107A,RPS5,TWNK,SQSTM1,NDUFS2,MRPL17,NPTN,TRA2B,NME4,MRPL41,NT5C3A,POLDIP2,MRPS7,MRPL20,MRPL10,MRPL12,CDK7,MRPS34,ATP5PO,CZIB,NDUFA5 |
| 9.824e-07 | -13.83 | UCHL3 (ubiquitin C-terminal hydrolase L3) | protein interactions | 7347 | 175 | 79 | 19454 | 5460 |
XRCC5,PEBP1,HELLS,DDX39B,DDX5,TTC1,GPX4,PGK1,HSPA8,HNRNPH2,GPC1,EEF1G,UCHL3,HSP90B1,ACAA2,ZMYM6,TPD52L1,EIF4A3,ENO2,UBE2S,ENO1,MSN,SNRPD1,TRIM27,TSN,TAGLN2,TRIM54,USP5,UBE2L3,CCNB1,PYCR1,NONO,BAG3,LMNB1,TDP1,MAPRE1,HSP90AA1,ZYX,HINT1,HSD17B10,CLPB,TRIM63,SRPRB,CSE1L,NEDD8,AHCYL1,SSRP1,UBE2A,TPD52,SMAD1,UBE2V1,SOX2,DDX39A,NFE2L2,RPN1,TUBB4B,OTULIN,ILF2,SOD2,ZRANB2,ACTA2,AIFM1,NT5DC1,SUMO3,TOP1,SPPL3,HNRNPL,RAB1B,TTC9C,CCT7,ZNF593,POGK,ISYNA1,CTNNB1,COPS5,PPIB,RPL10A,USP15,HNRNPD |
| 9.874e-07 | -13.83 | PSMA8 (proteasome 20S subunit alpha 8) | protein interactions | 143471 | 65 | 37 | 19454 | 5460 |
DESI1,PSMA2,PSMA1,PSMA5,PSMC1,PSMA3,METTL14,CDK1,PSMB7,PSMC3,HEXIM1,PSMB3,RAF1,PSMC4,CFTR,XBP1,PSMB9,SOX2,PSMD6,PSMB6,MDM2,PSMB4,PSMB5,PSMA6,CCNF,PSMB1,PSMC5,PSMD7,PSMD14,PSMG2,PSMA4,PSMB2,SYCE3,PSMD3,POLR3GL,H2BC9,PSMD1 |
| 9.986e-07 | -13.82 | SEC62 (SEC62 homolog, preprotein translocation factor) | protein interactions | 7095 | 493 | 187 | 19454 | 5460 |
STX5,PLPP4,PTDSS1,CTNNB1,DDRGK1,RINT1,CCT8,NUP42,STBD1,KDELR1,CSTPP1,TAPT1,LMBR1L,RETREG3,GGT7,TAX1BP1,ESR2,ATP6AP2,TMEM38B,SLC30A5,ZMPSTE24,EP300,MIA2,RER1,UFL1,CERS6,BET1,GOSR2,YIPF5,SEC62,FDFT1,CAMLG,SLC39A10,ARL6IP5,DNAJC1,LMAN1,FUNDC2,SLC38A2,TMPO,SELENOS,EDEM1,DHRS7,ZNF24,FAM20C,GAPDH,SMIM12,AGPAT1,MAP4,RUSF1,YIF1A,STX18,SRPRB,FKBP8,FKRP,SLC6A8,IPO8,SNAP29,PREB,UBIAD1,TFRC,SURF4,ATL1,SRP54,SC5D,DHRS13,GORASP2,ENDOD1,ATP1A1,TEX264,LPAR1,HSPA5,TSPAN5,SSR1,USE1,EIF2B3,RPA2,LEMD3,CYB5A,MAP1LC3A,WDR44,SLMAP,PDIA3,CDK5RAP3,C2CD2L,TMT1A,SCD5,SEMA4C,EMC8,AHCYL1,HS2ST1,RETREG1,SAR1B,RAF1,MACO1,GABARAPL1,FAF2,VAMP2,STIM1,RPN1,PLD3,CYB5B,ITGB5,ARF1,FAM177A1,GPR89A,SEC61B,RMDN3,REEP4,B4GAT1,ABHD12,TMED4,RAB11A,VEZT,LMNB1,ATP1A3,VMP1,SCFD1,CXCR4,NAP1L3,PGRMC1,NOTCH2,TOR1AIP2,ARMCX3,VAPB,FAM3C,EHBP1,PTPN1,HACD3,SRPRA,CDCA3,HSD17B11,EIF2B5,EIF2B2,ANKRD46,NOP9,EXTL2,EI24,TMEM199,HM13,ASIC2,ESYT1,POR,OSBPL8,STX8,NSDHL,TMX3,LPAR2,B4GALT7,PRDX4,PDE2A,CCDC47,LBR,MAP1LC3B,FAM169A,ELOVL4,ODR4,TMEM74,SEC63,VKORC1L1,HMOX2,ARFGAP3,GGCX,TYROBP,MGAT4B,FADS2,RPA3,DVL2,SPCS2,MTDH,RTN4,YKT6,CERS2,SLC7A1,GABARAP,TMEM209,CHMP2B,FUT8,ARHGAP1,SEC22B,RABL3,GABARAPL2,ST7,HSP90B1,GOLGA5,SLC12A2,TMX4,PDCL |
| 9.987e-07 | -13.82 | CERS2 (ceramide synthase 2) | protein interactions | 29956 | 203 | 89 | 19454 | 5460 |
RAB9A,VIPR1,SYVN1,LPAR1,VPS28,CDC42,CD2AP,GPR35,SSR1,LMNA,CSNK1G3,PRKCA,ELOVL4,PPP2R5E,GNAO1,CSNK2B,YES1,CEP41,NDN,SRC,VIRMA,ROCK1,TECR,PTPN11,ELOVL3,ATP5F1A,NRP1,ATP5PF,DLG1,PALM2AKAP2,SNAP23,YIF1A,CCNY,CPNE2,ELOVL6,ELOVL7,ATP5PB,NFE2L2,HRAS,CDCA3,RAC2,HSD17B11,TNFSF18,RELL1,DPP4,TMBIM6,P2RY1,TMEM106B,TSPAN15,TACR1,BIRC2,ATP5IF1,CNTN1,CERS6,PACSIN3,PYGB,COIL,SLC19A2,SEC62,OTULINL,ELOVL1,S1PR4,SEC61B,GPR173,RETREG3,ATP5F1B,ATP6AP2,EFNA5,ESR2,GPR17,KDSR,FAS,LAMTOR1,HSP90AA1,TMT1A,ATP5F1D,FLOT1,RPN1,GNAZ,GNAQ,CD63,TSG101,SPTAN1,INA,OPRL1,VPS26A,PTPN5,LAMP2,AGR2 |
| 9.987e-07 | -13.82 | PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 54623 | 203 | 89 | 19454 | 5460 |
MSL2,SSRP1,RUVBL1,VDAC1,KRAS,RPL31,RBPJ,ZRANB2,TULP3,SOX2,SUPT5H,SUMO2,FBXO32,PHB1,THOC2,HSPB1,DDX23,SKIC8,XPO1,IFI16,COIL,STAU1,FXR2,DCTN3,PSMA3,EP300,YAF2,XRCC5,RCCD1,SNRPA,SMARCD3,PGRMC1,ACTL6A,APEX1,ESR2,SNRNP40,POLR2F,CDC7,CYB5R3,H1-1,RIT1,FTSJ3,SNRPB,TTC33,PCCB,RNF40,GRB10,MYC,MDC1,RNF20,H3C1,PC,EMC2,ATP5PF,TCOF1,PHC1,NUPR1,POLR2G,CDK8,CDK9,PTP4A3,PRNP,TOP1,TES,EEF1AKMT3,CSNK2A1,COX5A,HMGB1,FBXW7,TCEA1,PML,BAP1,RPA3,ACACA,H2BC11,RPA2,ELP3,MYLIP,SYT2,CSNK2B,ENO1,ZNF330,UBE2H,CDC73,ATP1B3,PPP1CC,CIAO1,PTPN11,HSPA14 |
| 9.991e-07 | -13.82 | TUBG1 (tubulin gamma 1) | protein interactions | 7283 | 366 | 145 | 19454 | 5460 |
STUB1,RPS3,ZBTB33,TUBA1B,GANAB,RPL13A,TXNDC12,RPL10L,UBB,CDC20,RPL22,PDCD5,CEP97,RPS17,RPL26,RACGAP1,DTL,UBE2H,RPA3,BAP1,NBN,RNF113A,SQSTM1,GTF2I,NAPG,RPS15,FBXW7,TMUB1,HSPA5,RPS14,SPTBN1,NTPCR,RPA2,MRPS34,RPLP0,RPL26L1,PARD6A,HAUS2,COQ8A,COX4I1,RPS16,ARF6,CGAS,PRNP,TMPO,CDC5L,ERCC3,MZT2B,TUBG1,RPL24,H2AC4,RPS2,RPL10A,PSME1,RPL3,POC1B,ZC3H11A,CAMK2G,OLA1,RPS13,FASTKD5,RPL17,PRDX4,ANGPT1,TP53,CCT5,EEF1A1,CD2BP2,HBP1,PPP4C,LMBR1L,TRIM44,RPS9,TUBB,ACTB,MYC,CUL3,SAMHD1,CCT2,FTSJ3,BRCA1,H2AZ2,YWHAZ,HSP90AA1,PFDN2,PFDN6,HSPA8,HADHA,COIL,SKP1,MRPS7,SYK,NDE1,TIMM13,CTBP1,CSNK1A1,RAB35,PHB1,MAGED2,SPINT2,RPLP2,RPS10,TCP1,SPTAN1,RPL7,CACYBP,HSP90AB1,LRWD1,CCT7,LAMP2,PIK3R1,TRIM8,PFDN5,RPL6,YWHAH,XPO1,SPATA2,DDRGK1,CDK5RAP3,DDX23,POU5F1,RB1CC1,PEX3,RPL23,HSPD1,RPL31,CCT8,FGF3,BAG2,KRAS,PFDN1,RPS4X,RAB8B,RAF1,TOP3B,FAF2,SOX2,TUBA1A,EZH2,RPN1,TUBB4B,NME1,RPS11,RPS23,CSTPP1 |
| 1.003e-06 | -13.81 | PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha) | protein interactions | 5518 | 632 | 232 | 19454 | 5460 |
SLC25A3,FKBP10,IER2,FOXS1,EHD1,PSMC1,PPP2R3A,PPP2R2C,CRY1,FBXW4,SERTAD2,DUSP9,LSM14B,HSP90AA1,RHOB,MCM3,SAMHD1,CUL3,RAB11A,GRB10,OTUD6A,TNPO3,DYNLL1,TAB1,PRDX2,FAM43A,SNRPD2,ARPP19,BAD,CHMP4C,PPFIA2,EZH2,CTNNA2,RPN1,SKA3,GFPT1,E2F4,RAF1,PSMD12,G3BP1,SCD5,HSPD1,PDCD10,HNRNPA1,HR,PPP2R5A,PRDX1,PSMD3,DHX15,CEP19,SLMAP,EGLN3,CCAR2,KCTD10,SLC6A2,ARHGAP25,NABP1,PPP2CB,TRAF3IP3,CARHSP1,CDK1,CCND1,SEC22B,ATG16L1,PSMC4,POLDIP2,FBXW7,SMC4,SQSTM1,IDH3A,SIRT7,RPA3,SOD1,DVL2,SMAD2,NAPA,STK24,TXNIP,CTNNBIP1,FBXO7,DUSP10,VIRMA,CTTNBP2NL,MGST3,MSN,GANAB,CCNF,STUB1,PPME1,PPP4C,GINS4,EEF1A1,MAP2K3,FAM13B,SNRPG,RIGI,VTA1,CAMK2G,CTNNBL1,SERTAD1,HSD17B10,KLHL15,PC,HAPSTR1,SIKE1,RAB1A,TFPT,PSMD7,FOXC2,CAV1,CDK9,PRNP,RCHY1,SMAD3,PPT1,FBXO42,PAFAH1B1,SYK,TOMM22,ATP6V1C1,RNF41,STAU1,UFL1,EP300,STK26,HSPA8,HDAC5,FOS,THOC6,CKB,SNRPB,BTF3,PSMD1,MYC,ESR2,POLR2B,PPP5C,FBXO22,PSMD6,MRPL13,PRMT5,DLST,LMBR1L,MOB3C,PLS3,EEF2,ANAPC13,SUPT5H,MAX,RAB18,HNRNPF,PSMA1,RPAP3,CTTNBP2,YWHAB,AGR2,CTNNB1,DDRGK1,YWHAG,PPFIBP1,WWP2,IFI16,MACROD1,VAMP7,SUMO2,ZNF511,RPS10,PPFIA3,ACACA,LUC7L3,CYC1,UBE2M,USE1,RPA2,CFTR,CDC42,MARS1,HSPA5,GRPEL1,RNF113A,DERL1,PML,BAP1,UBE2H,RBM7,PTTG1,PDCD4,ATP1A1,RC3H2,ZFAND6,DNAJC5,GSTK1,FGFR1OP2,AKT1,CLCN6,UBA3,CDC20,SMURF1,ADRM1,DAPK1,INTS12,PPP2R5E,CSNK2B,MOB4,PSMC5,TBCCD1,UQCRC2,RPS3,TAF2,PSMC3,PLAAT3,TP53,RPSA,CDK4,CENPM,RAP1A,DUSP19,MEPCE,CDC40,PSME1,NOSIP,SNIP1,MAP1B,USP15,MAP4,CDK12,BCL10,TPM3,COPS5,CDC5L,ARL6IP5,FZR1 |
| 1.007e-06 | -13.81 | POLR1A (RNA polymerase I subunit A) | protein interactions | 25885 | 189 | 84 | 19454 | 5460 |
POLR2B,ESR2,BCCIP,MAD2L2,VIRMA,SRC,COPE,FBXO22,YES1,POLR3B,PTEN,POLR2F,POLR3H,CRYBB3,LMBR1L,ENO1,FBLN5,NFKBIB,PFDN2,NRP1,RPS5,RIT1,POLR1B,PFDN6,TEX19,BRCA1,ATG3,FBXW11,SMARCA5,MYC,RRN3,TRIM52,POLR1H,SKP1,FBXW7,STAU1,RPA3,SIRT7,TRIM10,PIH1D1,RPA2,RPRD1B,HSP90B1,FAXC,POLR1D,CDK7,ATG16L1,NOP58,GFOD1,SPPL3,HNRNPL,POLR2I,SHPRH,RPL9,RPRD1A,POLR2L,ASB7,RPL10A,IKBKB,H2AC4,ECD,CSNK2A1,DDRGK1,NFKB1,MOV10,PDRG1,VTA1,SSRP1,ANP32B,KRAS,DNAAF10,RUVBL1,KPNA2,RPAP3,RUVBL2,TCOF1,POLR2G,POLR2C,POLR2D,NUPR1,RPAP2,EEF1A1,TAF1D,LGR4 |
| 1.011e-06 | -13.80 | Immune System | REACTOME pathways | R-HSA-168256 | 2101 | 751 | 10285 | 3229 |
C1QC,OLR1,FBXW11,ITK,DLG4,CTSC,CREB1,TRIM32,PIK3R1,CCL19,H3C1,CDKN1B,IL1R2,TMBIM1,TIMP1,UBE2A,ELOC,TLR4,HSPA8,DEFB121,PPP5C,AGO1,WASF3,BPIFB4,MX1,ATP6V1E2,CD80,FGL2,FGF17,ELMO2,TICAM1,RAB5C,KLHL9,AP2M1,TOM1,NFKBIB,FCAR,HERC3,MAPKAPK3,CD4,NCR3LG1,MAPK10,TRIM29,TRIM22,CXCR1,RNF7,PPP3CA,NEFL,UFL1,TRIM36,ANAPC2,FZR1,SPRED2,MYD88,FCER1G,KLRF1,ATP6V1C1,TLR9,PSMB3,PEBP1,YES1,SNAP25,FABP5,STX1A,SLPI,YWHAB,TRIM34,STAT2,PNP,UBE2S,SEC13,IL10,CNTFR,PADI2,EIF4E3,FRS3,IL7,TMEM30A,DUSP9,TNFSF15,CD200R1,VAMP3,TRIM8,CD1A,CCNF,TNFAIP6,IL15RA,RAB9B,IL34,ATP6V1G2,TXNIP,PDAP1,MAP3K14,DEFB1,CAMK2G,FBXO30,ASB3,HP,SEC61A1,TP53,CD86,XAF1,PLD3,PTPN1,CFL1,EGR1,COTL1,UBE2E2,PRCP,NLRP3,GCA,POLR3B,IFI27,RAB6A,DUSP3,RIGI,ACTR1A,SYNGR1,ATP6V1D,VEGFA,PSMA4,AGER,PSMB6,TMT1A,CDC20,CD3G,CCL2,PSMB1,TNFRSF1B,AHCYL1,PSMC4,HECTD1,IRF4,RAB27A,PTPN11,SERPINA1,POLR3H,POLR2L,LILRB4,STAT5A,TNF,PELI1,CUL2,LTA,SERPINB6,SHC3,ICAM1,TNFRSF9,DHX9,NUP37,PRKCB,EIF2AK2,CSF2,TNFSF8,JAK1,CAND1,MAP3K11,HCST,JUP,FBXL14,UBE2M,BIRC2,TRIM26,RNF126,NUP153,IL2RA,FBXW4,NFKB1,MET,JUNB,LTBR,HUWE1,IRAK4,SERPINB10,PIP5K1A,IL1A,TANK,KIF3C,ANAPC13,DNASE1L1,ELK1,MX2,DET1,AREL1,TRPC1,TNFSF12,TLR10,FGF22,RBCK1,CCND1,FBXL19,HMOX2,PLPP4,STAT6,CD59,MBL2,IRF7,PSMD1,TAPBP,CNPY3,NCKAP1,ISG20,DYNC1I1,CTSD,CGAS,AP1S2,PSMA1,FBXO31,IFNGR1,RASGRP3,CTSK,STOM,SEC22B,UBE2W,NDN,RHOU,SEC61A2,IL22,DNAJC3,DEGS1,TRIM62,GSTP1,PSMB5,FOS,ADCY3,TRIM35,IL18BP,CD1B,PRKACB,CXCL8,DSN1,CD40LG,ORAI2,ASB11,ATP6AP2,TRIM68,NECTIN2,GHR,RACGAP1,WWP1,TAX1BP1,HEXB,MEF2A,CDKN1A,KPNA2,ICAM2,FGF7,ATP6V0B,CD47,KLC2,RLIM,HEBP2,NEU1,RNF182,SQSTM1,SIGLEC5,HBEGF,PTPN22,CCT2,TLR8,ASB7,ARF1,DEFB124,MDM2,DYNC1I2,WDR83,CD226,PIAS1,KPNA1,KBTBD13,EP300,FGF10,LAMTOR2,CCR6,CYFIP2,MADCAM1,AKT3,RNASEL,IL12A,SPSB1,ARPC3,EEF2,PDIA3,IER3,TRIM46,SPRED1,SEC23A,TICAM2,HMGB1,RAB18,KLRD1,PSMB11,CCL20,SEC61B,NCKIPSD,IL4,CDC16,SNAP23,CSNK2B,MIF,MYLIP,JAK2,NUP50,TRIM63,IL6,SOX2,CD46,CAMP,UBE2L3,PSEN1,RSAD2,CALML5,PPP2R1A,ASB8,LILRA2,ATP6V1G1,ILF2,PRL,DEFB114,TRAPPC1,POLR3F,COL1A2,TNFAIP3,GSK3A,GRAP2,FAF2,RNF41,TRAF6,PSMB9,LAT2,IL15,IFI6,SOCS3,ACTB,FCGR2A,PROS1,ISG15,SELL,CD58,STIM1,PELI3,ASB1,NDUFC2,IL23A,CCL3,IRF1,CD200,NME2,HECTD3,ROCK1,PPP2CB,SMURF1,BCL6,ACTR1B,UBE2V1,KIF2A,NUP42,PSMB2,TUBB,IL20RB,PEA15,IL18,JAML,TMEM179B,PSMC1,KLHL22,IL3,PHB1,OPRM1,SHC1,SOCS2,LYZ,CDC23,CCL11,NUP62,TBC1D10C,CTLA4,DNM2,S100A8,IL2,JUN,TYROBP,B2M,UBE3A,CD28,BRAP,CSK,SAMHD1,LILRA3,LAMP2,INPPL1,CLEC2B,IRF2,CDC26,PRKCA,SOCS5,PDCD1LG2,BRI3,NCSTN,EEF1A1,AP2S1,ENPP4,FBXO22,MME,PPM1B,NUP107,STAT1,CTSA,ATF1,EIF4A3,CAB39,PIK3R3,LTB,MYC,EIF4A2,NLRP1,KBTBD6,RAB31,DUSP10,PSME2,DCTN6,STUB1,HSP90B1,IFNB1,FASLG,CASP4,IFNA2,PSMA5,SAR1B,AP2A1,EIF4E,DCTN4,CD247,IFNG,ICOS,CDC42,TLR6,KLHL25,ARMC8,CTSB,TNFRSF14,TRIM3,PI3,MRC1,FBXL3,SRC,SRP14,FBXO9,TLR7,YWHAZ,NFKBIA,TBK1,PPIA,KIT,IL5,PIP4K2C,FBXO7,UBE2K,POLR3GL,FGF16,VWF,IFNA10,RAP2C,FBXL4,CAPN1,UBE2N,PRDX4,BTN2A2,UBE2D3,APEH,HSPA5,CSH1,RPS27A,IL1RAP,ANAPC11,ITGB5,CST3,CLEC7A,DUSP1,PGM1,KLRC2,B4GALT1,FGFR1,PSMA2,UBE2E3,ADCY2,RNF34,VAV2,CD81,PSMD14,POLR2F,CD40,SIAH2,LCP2,SPTBN1,PTPN4,RAG1,ELMO1,BPIFA2,ANGPT1,UBE2B,PDE1B,MAP2K3,ICAM3,IRF8,CCT8,PRKCE,XRCC5,RNASET2,TLR3,CALR,BST2,BAD,IL1B,CD63,CD274,GOLGA7,FBXO44,EIF4E2,CXCL10,MYH2,PAQR3,UBE2H,IFI16,PIK3R2,IL2RG,OAS1,HSP90AB1,DUSP6,GH1,CISH,KRAS,VAMP8,NPC2,TNRC6C,MAVS,CD36,CAPZA1,FGR,FTH1,TLR1,LGALS3,DEFB115,CD79B,PAFAH1B2,CCR2,SURF4,GLIPR1,AKT1,PIK3CA,HSP90AA1,BCL10,TAB2,DEFB116,MAP2K6,CCR5,CUL3,OSM,SIKE1,BCL2L1,TUBB4B,IRF9,PSMC5,ORMDL3,TXN,PSMB10,CD1C,IFI35,PSMD3,FBXO32,PSMB7,PLAC8,PSMA3,CXCL1,TTR,TRIM11,PGRMC1,AP1M1,CBL,FBXL7,IFIH1,SKP1,UBA3,IL12B,SERPINB1,PSMD7,UBE2V2,RAB3D,HERC4,CMTM6,RAP1A,PGAM1,TIRAP,LAMTOR1,RETN,DEFB129,BATF,MT2A,LILRA1,NUP35,UBE2D1,TRIM5,PSMD6,DNAJC5,GGH,RAB37,TRIM10,S100A11,MAP3K3,FCN2,EDA2R,FGF23,CLEC6A,PDE1A,SH2D1A,PPP2R5E,NCR3,RAB3A,IFNA13,CCL5,CYB5R3,RHOG,S100B,PPP2R5A,PRKCQ,RAP1B,UBA52,CD209,ATG7,RASGRP2,MICB,RCHY1,COMMD3,TRIM37,PIK3AP1,GAB1,PYGB,CHI3L1,SNAP29,ZNRF1,RNF14,CD1D,RNASE6,PSMA6,RNF144B,MCL1,IL2RB,GDI2,KIF3B,IRF6,PSMC3,IFNAR1,TRAF2,TOLLIP,TRIM6,PSMB4,ATP6V1A,SEM1,CD14,CPNE1,ANAPC4,DCTN3,LY96,TLR5,PDCD1,IL17F,ZBTB16,CRKL,CCR1,COMMD9,RAP2B,UBE2G2,MEF2C,UBE2F,UBB,HBB,PSME1,CD34,NCK1,POLR1D,TRAF7,AKT2,CLU,PYCARD,TNFSF18,IL6ST,CHGA,WASL,FTL,IRF3,FCGR1A,PSMD12,BPIFB1,DYNLL1,SARM1,ATP8A1,FGF3,FCGR2B,WSB1,FBXW7,SIAH1,RNF115,SERPINA3,ACTR2,PTEN,SPTAN1,KLHL3,STBD1,TRIM21,TAB1,BIRC5,LEAP2,CYSTM1,TREML1,FGF1,RAB14,PLEKHO2,MAP2K1,ATP6V0E1,SYK,TRIM45,RAF1,CAPZA2,LILRB1,PSMD10,SDCBP,IL13,MOV10,PML,SVIP,MMP9,HRAS,PRDX6,IFIT2,AGA,YPEL5,SUMO1,LAMTOR3,CREBBP,SLC2A3,CTNNB1,TNFSF13,ARPC2,CSTB,ITGAV,PSMD4,SEC61G,TLR2,IKBKB,PAK2,IDH1 |
| 1.021e-06 | -13.79 | PSMD5 (proteasome 26S subunit, non-ATPase 5) | protein interactions | 5711 | 113 | 56 | 19454 | 5460 |
PSMD3,PSMD10,AGR2,PSMD7,CCDC92,ID1,PSMB4,PSMB5,PSME2,HRAS,COPS2,PSMB1,PRNP,PSMB9,TFCP2,PSMC3,PPME1,PSME1,UBE3A,PSMA2,PSMA5,KRAS,PSMA1,RIGI,PSMB10,PSMD12,PSMA4,PSMB2,MYC,USP14,GMPS,BAG3,AR,MCM3,PSMD1,PSMD14,PSMA6,PSMC5,ADRM1,PSMD6,PSMD4,PNP,VIRMA,ESR2,DYRK1A,PSMB6,PSMB3,PSMC4,LNX2,EDEM3,PAAF1,LMNA,PSMB7,PSMA3,PSMC1,RNF11 |
| 1.023e-06 | -13.79 | BCL2L13 (BCL2 like 13) | protein interactions | 23786 | 145 | 68 | 19454 | 5460 |
VIRMA,MGST3,TUBB,ETNK2,GTF2F1,OPTN,VAMP3,PLP1,BAD,CYB5R3,PLN,FIS1,HTRA2,CHCHD4,TOMM40,HMOX2,TOMM20,BNIP3L,CERS6,CERS2,SLC7A1,NPTN,TMEM254,AKAP1,RAB5A,MAVS,ACP5,SMARCD3,SOD1,JAGN1,SPOCK1,EXD2,TMUB2,CDC42,GABARAPL2,TOMM22,AGTRAP,BET1,TMEM97,CRB3,AIG1,COX14,BOK,AIFM1,CAMLG,MGMT,POR,SLC35A1,MARCHF5,SLC25A46,PLPP4,FKBP8,GALNT2,IMMP2L,TNF,KRAS,HNRNPK,ADIPOQ,ERG28,BCL9,STX8,STX12,CDK5R1,ITGB5,TOP3B,NETO2,MTCH2,JPH4 |
| 1.035e-06 | -13.78 | CARM1 (coactivator associated arginine methyltransferase 1) | protein interactions | 10498 | 304 | 124 | 19454 | 5460 |
HNRNPF,KRAS,CCT8,PABPC1,THNSL1,SLC39A7,PCNA,EZH2,JPT2,SMARCB1,MED9,SUPT5H,RAF1,ARFGAP1,B3GNT2,NUDCD3,DYNC1I2,SUMO3,DHX15,HSP90AB1,CCT7,LRRC61,CACYBP,EGLN3,GSTA1,PRCC,FBXO32,EED,DROSHA,FOSL2,CBL,HNRNPD,RAB5C,CDC26,IFI16,PSMD3,CTNNB1,HNRNPA1,SKP1,ATP6V1G1,FOS,XRCC5,SNRPA,RAB5A,EP300,PPT1,CTBP1,RTF2,EIF4B,PSMB3,MTMR6,PSMD6,ACTB,STAT2,DES,PRMT5,BRCA1,KIAA1191,BLVRA,RIT1,ILK,CUL3,RAB11A,CUL2,MYC,CREBBP,SMARCE1,ATG4A,KPNA2,RPIA,HNRNPK,H3C1,CAMK2G,CAPZA1,TICAM1,PSME1,RAB1A,FAF1,TP53,CCT5,KBTBD4,GGCT,ESS2,NECAP2,CAND1,RAB39B,POLE3,MAP2K6,PTPN1,LDLR,TRAPPC2L,CNN3,IRF4,NFKB1,COPS5,FBXW7,KDM1A,MARS1,GABARAP,HSPA5,FABP4,FBXO9,UGP2,RPA3,SLC39A9,RPA2,LMNA,FUT8,PAAF1,CDK7,ADRM1,PPAT,STAT5A,CTNNA1,CCNF,CREB1,UBE2I,RPS20,B4GALT1,HEY2,CHRAC1,SH3BP5L,UBE2H,RAB2A |
| 1.035e-06 | -13.78 | RRP1B (ribosomal RNA processing 1B) | protein interactions | 23076 | 304 | 124 | 19454 | 5460 |
RPL3,RPL23A,ABCE1,H3C1,NUP107,TP53,AURKAIP1,DNAJC2,ILF2,NUPR1,SRP72,SRP14,ALYREF,KRR1,RPS16,DNAJC1,FZR1,TOP1,RBM42,SURF6,ZBTB2,GRSF1,CSNK2A1,MPG,H2AC4,SNRNP70,BRD3,RPL10A,RPA3,NLE1,SIRT7,EXOSC4,RNF113A,RAB9A,DGCR8,NPM3,FBXW7,RPL4,AATF,FGF13,CDK7,KLF12,RPA2,RPL26L1,RPLP0,PRKCA,KLF4,LUC7L3,CCNF,PSPC1,TNFRSF1B,EIF2AK2,ZNF330,CTTN,FGFBP1,CSNK2B,PRKRA,GSK3A,RPL13A,PPP1R10,SRPK2,VIRMA,RPL22,RPL7A,PRKACB,USP14,PPP1CC,MECP2,SDF2L1,RC3H2,ATP1A1,UBE2H,RPL31,TRIP4,RPS24,G3BP1,RPL28,RAF1,MAGEB10,SOX2,DCAF8L2,SART3,RHOBTB1,RPL8,PHB1,SRSF1,FAM98A,BAZ1B,IFI16,WWP2,HNRNPA1,MAP3K14,DDRGK1,DDX23,LHX2,DRG1,ARMC8,HSPA8,UFL1,ZNF692,STAU1,G3BP2,MRPS7,SYK,TOMM22,MTF1,BET1,PPP1CB,TACO1,RPL7L1,RPL35,SNRNP40,CBX5,ESR2,APEX1,MYC,CUL3,RAB11A,ZNF668,PSKH1,H1-10,H1-1,VMP1,CDKL2 |
| 1.037e-06 | -13.78 | Proteasome_sua/b | interpro domains | IPR001353 | 19 | 16 | 18521 | 5414 |
PSMA2,PSMA5,PSMB6,PSMA1,PSMA3,PSMB4,PSMA6,PSMB5,PSMB3,PSMA4,PSMB10,PSMB9,PSMB2,PSMB1,PSMB7,PSMB11 |
| 1.046e-06 | -13.77 | API5 (apoptosis inhibitor 5) | protein interactions | 8539 | 178 | 80 | 19454 | 5460 |
LMNB1,CKB,OSGEP,PDCD4,ZBTB38,ACO2,BAG3,SNRPB,RPL13A,RPL35,ACTB,NMI,EIF4A3,PPP2R5E,SF3B4,SNRPD1,RPA2,STAT6,RPLP0,OXSR1,TPT1,EHD1,GTF3C4,RPL4,STAU1,SAP18,SOD1,DDX39B,THOC3,RPA3,BAP1,RPL27,SNRPA,EP300,YAF2,LSM12,TRIM5,DRG2,RPL24,RPL23,POU5F1,RPS2,RPL6,CTNNB1,NT5C2,YWHAG,RPL7,RPL35A,RPS16,DCUN1D1,HNRNPL,DHX15,CDC5L,RPL8,RPL12,EED,MAD2L1BP,EZH2,NUPR1,GNAI3,RPL18,SF3B5,OSGEPL1,RPL15,DDX39A,XPNPEP1,THRAP3,HNRNPK,H3C1,LASP1,ZNF609,RAD21,RPS4X,RPL28,HNRNPA2B1,PABPC1,RTCB,DHX9,RPL3,EWSR1 |
| 1.051e-06 | -13.77 | Toll-like Receptor Signaling Pathway | WikiPathways | WP75 | 103 | 61 | 5310 | 1910 |
TLR5,TAB1,TBK1,IL1B,JUN,TLR8,PIK3CG,PIK3R2,IFNA13,IFNA2,CXCL11,TIRAP,TOLLIP,TICAM1,TLR3,TLR1,AKT1,CD80,MAP2K6,MAP2K3,MAP2K1,IL6,IL12B,TLR4,TRAF6,PIK3R1,IKBKB,CCL5,MYD88,CXCL10,NFKBIA,IFNA10,IFNAR1,IFNB1,AKT2,SPP1,CD86,LY96,PIK3CA,TNF,IRAK4,NFKB1,CD14,PIK3R3,CXCL8,CXCL9,TLR9,FOS,CD40,MAPK10,TLR6,TAB2,IRF7,AKT3,TICAM2,TLR2,STAT1,IL12A,TLR7,IRF3,CCL3 |
| 1.058e-06 | -13.76 | GPN1 (GPN-loop GTPase 1) | protein interactions | 11321 | 121 | 59 | 19454 | 5460 |
SURF2,CCNF,POLR2F,POLR3H,GPN2,POLR3B,MED17,FBXO22,POLR2B,CUL3,LMO2,TMEM183A,BRCA1,BICD2,LRRC20,ATG3,RIT1,POLR1B,UBE2H,PFDN2,PML,RPA3,HNRNPH2,HSPA8,FBXW7,GON7,POLR1D,WWP1,ARMCX3,P3H1,RPA2,RPRD1B,PIH1D1,POLR2L,RPRD1A,TCP1,POLR2I,HSP90AB1,EGLN3,WWP2,CSNK2A1,XPO1,CRTAP,HNRNPD,TCOF1,CCT8,FAM168A,RPAP3,KPNA2,RUVBL1,KRAS,ZBED1,CCT5,RPAP2,SOX2,POLR2C,PPME1,POLR2G,POLR2D |
| 1.065e-06 | -13.75 | VTI1A (vesicle transport through interaction with t-SNAREs 1A) | protein interactions | 143187 | 58 | 34 | 19454 | 5460 |
NAPA,SCFD1,LAMTOR1,LAMP3,STX16,TMBIM6,LAMP2,RAB2A,EDEM1,VAMP5,RAB5C,STX6,APEX1,ARF6,HNRNPL,VTI1B,TMEM74,STX10,VAMP3,STX12,TFRC,PTP4A2,RAB4A,SNAP29,SEC22B,BET1,STX11,STX7,VAMP8,NAPG,STX18,RAB9A,RAB5A,STX8 |
| 1.066e-06 | -13.75 | OTUD1 (OTU deubiquitinase 1) | protein interactions | 220213 | 167 | 76 | 19454 | 5460 |
FUBP3,PPP2CB,SMAD3,AIFM1,BRD9,SEC23A,MCL1,CCAR2,TCP1,SNRPD3,EIF2S1,HSP90AB1,CDC5L,PPIA,TMPO,PEG10,IRF4,STOML2,PRDX1,PSMD3,CTNNB1,XPO1,LANCL2,RPL23,HSPB1,PABPC1,CCT8,SLC25A10,RPS24,BAG2,RTCB,FARSA,KPNA2,TNF,RPL17,PRDX4,TP53,RPSA,CCT5,RPL15,RPS7,PPIF,DDX39A,NUP153,PPP2R1A,TMEM165,TUBB4B,RPN1,RAD23B,DHRS7B,VDAC2,SEC61B,PSMC5,RPL13A,RBBP4,UMPS,ATP5F1B,RPL10,TECR,SMURF1,CUL3,SLC25A1,MAT2A,MCM3,CHCHD4,CDKN2AIP,IRF3,EEF1G,YTHDF1,IRF7,GTF2I,TOMM20,UBA52,NOTCH2,CDK1,ATP5PO |
| 1.068e-06 | -13.75 | SLC25A24 (solute carrier family 25 member 24) | protein interactions | 29957 | 129 | 62 | 19454 | 5460 |
SLC25A4,ATP5F1B,VIRMA,PARL,ESR2,APLNR,SCN2B,UQCRC2,TMEM108,NDUFB10,TUFM,ATP5F1A,TOMM40,SLC15A1,PHB2,EMC1,PDHB,HSPA5,RNF11,PML,RPA3,SLC39A9,SLC22A6,STOM,RPA2,VAPB,ATP5PO,COX6C,NDUFA5,MPV17,TOMM22,CFTR,AGK,SPPL3,SLC25A12,OPRL1,ATP5PD,EGLN3,PHB1,AIFM1,CYB5A,AGR2,DPP4,CD80,FLOT1,RIGI,PDE2A,NDUFA4,SFXN1,CHST10,SLC25A5,EMC2,BSCL2,AQP3,NDUFS6,PDHA1,E2F4,FBP1,APOO,FAF2,LPAR6,MGARP |
| 1.068e-06 | -13.75 | LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3) | protein interactions | 8649 | 129 | 62 | 19454 | 5460 |
TOMM70,NDUFB4,MRPS9,PTPN1,RAB31,SSBP1,TFE3,ATP6V1A,PRR3,RHOG,RAB5C,LAMTOR2,SLC38A7,MRPS35,MOV10,SLC38A9,VRK1,RRAGB,KRAS,MRPL22,NDUFB5,PTRH2,VAMP2,TFCP2,MRPL51,AP2S1,ILF2,NDUFA2,MRPL47,RPS7,SNAPIN,YES1,RALA,RAB14,BORCS7,SRC,UQCRQ,RHOB,NIF3L1,LAMTOR1,RALB,RAB2A,NDUFB7,TOMM40,ADAMTS10,STX7,PIP4P1,SPCS2,RAB9A,PICALM,BORCS5,MAP2K1,CD46,PTP4A2,NUDT12,SUFU,MPV17,TOMM22,WDR83,RRAGA,BORCS6,CDC42 |
| 1.071e-06 | -13.75 | SBNO1 (strawberry notch homolog 1) | protein interactions | 55206 | 70 | 39 | 19454 | 5460 |
SRSF2,KRAS,STAU1,MCM6,MSH6,ARL6,PTGES3,SSRP1,RPA3,PML,HSPA8,RTN4,NUP50,EP300,CBX3,CDK8,RPA2,P3H1,TP53,GTF3C4,CDC42,MED17,ZBTB2,VIRMA,ESR2,PBDC1,GSK3A,PRMT5,SMAD4,ANKRD49,IVNS1ABP,RIT1,USP15,MYC,SUB1,H2BC9,NTAQ1,ACTR3B,MCM4 |
| 1.071e-06 | -13.75 | TPD52 (tumor protein D52) | protein interactions | 7163 | 95 | 49 | 19454 | 5460 |
MEAF6,PAIP1,PRNP,CACYBP,MRPS23,G6PD,THOC2,PHB1,MAP4,TSNAX,ATG9A,RAB5C,SOCS2,PTGES3,SEPHS1,MRPS11,PDIA6,DMAP1,RAB4A,SH3GLB1,TPD52,E2F4,SPG21,TENT5C,CLIC4,SRPK2,STUB1,ENO2,LAMTOR1,SPOP,PDCD4,CALU,RAB2A,SEC13,RAB11A,CUL3,AR,DNAJC5,BAG3,UCHL3,PIP4P1,BAP1,SNRPA,SOD1,RPA3,RPRD1B,TPD52L1,TPT1,MTX2 |
| 1.079e-06 | -13.74 | transferase activity, transferring alkyl or aryl (other than methyl) groups | molecular function | GO:0016765 | 62 | 37 | 18094 | 5411 |
GSTM2,RABGGTB,PDSS2,GSTT1,MGST2,GSTA2,UBIAD1,FDFT1,HPGDS,GSTT2B,TSR3,GSTM5,GSTO1,GSTA4,MGST3,GSTP1,HMBS,GSTO2,PTGES,DTWD2,ALOX5AP,GGPS1,SRM,DHPS,DTWD1,CLIC2,LANCL1,PGGT1B,GSTM3,GSTM4,COX10,GSTK1,PTAR1,GSTA1,MAT2A,NUS1,FNTB |
| 1.086e-06 | -13.73 | KCND3 (potassium voltage-gated channel subfamily D member 3) | protein interactions | 3752 | 42 | 27 | 19454 | 5460 |
XRCC5,HSPA8,SCN1B,EWSR1,HNRNPF,NDUFS2,G3BP1,RUVBL1,HSPA5,KCND3,LBR,CDK1,TLR3,KCNA2,UQCRC2,TUBA1B,HNRNPL,SPPL3,RAPGEF5,SRC,H2AC14,PYCR2,NONO,KCNIP2,VPS4A,DPP10,HSP90AA1 |
| 1.086e-06 | -13.73 | Psmb4 (proteasome (prosome, macropain) subunit, beta type 4) | protein interactions | 19172 | 42 | 27 | 19454 | 5460 |
PSMB3,PSMC3,PSMB7,PSMA3,PSME1,PSMC1,PSMA1,PSMA5,PSMA2,DNAJC8,PSMD1,FBXO7,PSMA4,PSMD3,PSMB2,PSMD14,DROSHA,PSMG2,PSMB1,PSMC5,PSMB5,PSMA6,CCNF,PSME2,PSMB6,ADRM1,PSMD4 |
| 1.088e-06 | -13.73 | regulation of gene expression | biological process | GO:0010468 | 5398 | 1725 | 18204 | 5365 |
MIR449A,MTA3,CXXC1,EMX2,ZFP1,FLOT1,JUN,PNP,MORC2,MIR885,CBX3,HSPD1,MIR1-2,RSAD2,USP2,MIR107,ZFP64,MIR190A,STOML2,FOXP1,UBE3A,RNF14,IL12B,MIR185,POLR3B,PCBP4,MSX2,MIR375,LILRA2,RBFOX3,MIR519D,MIR30B,MTG2,INHA,POGK,MIR548C,ILDR1,ZNF280B,ABCC2,MIR651,RGCC,TIA1,MYBL2,MIR593,MIR210,POLR3F,ZNF592,RMND1,POU5F1,MIR197,H3C1,MIR33B,SIN3A,LYAR,ELK1,EIF4E3,MIR92B,H2AC6,MIR99A,PRMT5,DRD3,MIR9-3,SELENOS,TANK,GMNN,ZMYND11,LMNA,ZNF862,MIR136,AKAP17A,BACH1,GPX1,LSM14B,ANXA7,TMEM106A,EP300,OVOL1,PIK3R3,WDR77,PHF21A,CTDSP1,CDK12,MSN,CRKL,TRIM24,ODAM,SNX12,AATF,MIR643,H2AC4,MLLT11,MIR206,GSK3A,RAMP3,KPNA6,DEDD,MAF1,TIRAP,BST2,MIR573,HEXIM1,ZNF22,HNRNPK,NOVA1,TRIM21,ATF4,SRGN,NRDE2,PPID,ANGPT1,ZNF609,MIR34C,CDK20,SRC,PRKRA,MEF2A,LGR4,MIR135B,ZBTB5,TENT2,BIRC5,IFNG,NTRK2,MIR551A,LMO3,IFI16,TCEAL7,METTL14,ACTR2,CTNNBIP1,AFAP1L2,UTP15,INSM2,PQBP1,IRF1,BMPR2,CELF6,EXOSC3,MIR542,MOG,TAL2,EDC3,MIR29A,TICAM1,SMAD9,MIRLET7I,MECP2,MIR181C,FCGR2B,ZNF32,ELP3,ATF3,STAP1,MIR653,SETD5,MIR205,KLF10,PCGF3,MIR599,MIR924,KMT5B,EIF4A3,CCN3,HNRNPD,WNT2,TAF9,SELENOK,TMIGD3,TRIM62,IRF2BP1,SCML2,ELF5,DUSP22,CSRNP1,MIR24-1,SMAD3,CCL19,HOXD12,PLAGL1,RNF40,MIR378A,TRIB1,MIR802,MIR1180,MIR181D,NUDT12,TICAM2,HP1BP3,MIR222,TRAF6,POU3F4,NFKB1,LRIF1,ZKSCAN1,ARG2,HLF,SUPT3H,PLP1,MIR937,FOS,PSPC1,CHI3L1,PRSS37,IRF2BPL,HNRNPF,RPAP2,TGIF2,HSP90AA1,SMAD5,H2AC13,KDM4B,MAGED2,CDK5R1,MIR190B,PSRC1,CD83,SASH3,MOV10,APLN,SAP30BP,KLF9,INPP5K,HTR2A,GATAD1,CREB1,FRMD8,TDRD7,PRDX3,MIR556,G3BP1,SPON1,MIR216B,HNRNPA1,WWP2,THOC2,GLO1,ZGLP1,EGR2,ARB2A,RPS27L,LILRB4,ZBTB42,TRIM26,ZMPSTE24,RUNX1,ZMYM2,GFI1,PKIG,IFIH1,MIR208A,WWP1,TAF2,CBFB,CD28,TAX1BP1,VGLL4,ZCCHC17,MSTN,BEND5,MEF2C,TRIM11,SP4,RC3H2,SMG5,CCNQ,PIWIL2,CDH13,GREM1,MIR940,ADTRP,MTDH,SOX2,PTPN22,NFKBIB,PDE8A,TRIM37,USP13,IRF2,HSBP1,ABHD14B,MIR612,RING1,PCNA,MXD1,ZBTB38,HNRNPH2,ACTA2,SRPK2,RBM7,NOTCH2,CRIP1,RASL11A,PAK6,METAP1,MIR144,TGFB2,CHP1,CRYBA1,ATP1B1,MAFG,CDK7,MIR20A,HBP1,CIRBP,TADA3,NFE2,BAZ1B,PRKCB,CTBP1,SHC1,ZC3H14,PAGR1,ZNF174,TRAF3IP3,ZNF250,ATP2B4,MIR708,MACROH2A1,RIT2,HUWE1,PTPN11,HDAC11,CKS1B,ENC1,TRIM27,TFPT,CDK6,NONO,FOXI3,HELT,FGFR1,ATXN1L,MIR155HG,SCAMP5,VGLL2,PIWIL4,ACSS2,MIR216A,IL21,CLEC7A,ZNF451,VPS72,MITF,IL13,MIR609,ZNF671,MIR34A,TAF7,TENT5D,IDO1,MIDEAS,SP1,RPL23,SFRP4,CCNA2,PTGER4,MIR626,DCP2,RNF20,TSPO,BTG2,ZBTB6,MIR711,GPNMB,JUP,RNF187,FZD6,ESR2,IER2,IL7,MIR1262,ITK,EZH1,RFXAP,SLC6A4,POLR2L,LSM6,RAD21,CNOT7,MIR934,GAPDH,MYRF,TGFB1I1,S100A10,LARP4B,BATF,AGER,MIR23A,ZNF304,MIR361,CXXC5,MIR495,YTHDF1,INO80C,ZNF770,EPHA2,CBX5,TRAF2,NMBR,TRIM6,RPS3,EEF2,FOXP4,ETF1,ADIPOQ,LBH,FGF17,ROCK2,YAF2,H2AZ1,MIR567,MIRLET7C,CGGBP1,MIR581,RHOH,MIR1277,MIR657,TFDP2,DIS3L,MTRES1,LDB1,XAF1,H2AX,SPINDOC,FBXW11,RAG1,OGG1,MIR424,PSMD10,CXCL10,TNFRSF14,SPHK2,JPH4,E2F4,LMNB1,HAX1,KLHL25,TENT4A,SMARCE1,ACTL6A,PPP1R12A,PPP2CB,MIR1224,CD274,FOXP3,ID4,ZNF581,TP53INP1,EIF4E,ZBTB2,PADI2,CHMP1A,PTP4A3,BAHD1,ZNF513,MACIR,MAGEC2,GNRH1,MMP14,DNAJB6,SFN,NACC2,MIR648,MIR96,ZNF507,HDAC3,IFNK,SMARCD3,MIR383,ZBTB16,ZNF24,MIR148A,PRKAG1,MIR454,MIR887,TP53INP2,RIGI,PAX6,GFPT1,SMYD3,TXNIP,WNT10B,MIR577,FUBP3,ACO1,DUSP26,RPS4X,ITGA2,SERTAD2,RPL26,VSTM2A,WNT7A,MIR374A,CEBPE,TGFB3,SIAH2,VDR,BAK1,MIR345,ZNF688,MIR877,TEF,PPP1R11,BRD9,NFKBIA,SAP30,CLK4,SIRT7,MIR331,TCF23,MIR130A,CYTL1,MIRLET7B,IL2,PAIP2,HIRA,CCND1,TSC22D3,MIR492,SOD1,AR,RPL13A,MED13L,XBP1,PID1,MIR450B,MIR10B,SMU1,DIO2,ATF1,RGMA,PHC1,TAF11,TCEAL1,MIR187,GNB3,MIR125A,FGF1,ACP5,CD58,CD40LG,PDE4B,TFEB,MIR140,MIR939,KLF3,CCDC85B,H1-3,SUPT4H1,ROCK1,MIR15A,PHAX,PIK3CA,CD47,TAF10,IL17F,TAF1D,APEX1,ZC4H2,CAPN2,FZD4,KRBOX4,SOX14,DEK,CAMK1,KLF1,PIK3R2,MIR944,PRKACB,YWHAZ,CCL1,OSM,MIR301B,VEGFA,MTA2,CLK1,IL23A,ZNF704,SATB1,NSMCE3,PPM1B,NUDT16,MTPN,FGF23,EIF3E,TESC,S100A8,NOG,PRR5L,EAF2,EWSR1,FBXW7,PRDX6,MALSU1,TRIM5,MIR129-2,SELENOT,APOBEC3C,NLRP1,FGF16,SYK,PITHD1,HILPDA,BOLL,HNRNPL,MED9,MAGEA4,ZSCAN25,TRIM32,GPAM,UBE2L3,TRMT112,RASD1,CNOT6L,LAMP3,MED23,SERTAD1,MIR363,APBB3,VSIR,MIR101-1,VAMP3,PIAS1,MIR32,MIR632,ZBTB39,CDK4,CYRIB,TBK1,XRCC5,C1D,APOBEC3A,TACO1,ZNF287,H2AC1,MIR373,SERTAD3,CLEC9A,CHCHD2,PSMC5,IGF2BP1,PDE2A,CIART,ARL2BP,RBM42,EIF5B,POU1F1,DNAJC1,HEY2,IRF3,MAP3K12,STK3,ZNF518B,KLF12,MIR1225,SETD7,MIF,HNF1B,RWDD3,EIF5A2,MIR132,BCL10,IL12A,ZNF652,MIR302B,FLCN,MIR484,MIR761,AGO1,CRYAB,NUPR1,SECISBP2L,CCL5,DMTF1,RORB,MIR3173,TLR3,TRIM68,RPS14,AKAP12,FAM98A,MIR146A,NKRF,DGCR8,SCML1,THAP1,MDC1,ILF2,IL4,MIR504,MIR662,TADA1,SPIN3,MIR452,ING2,DKK3,RUVBL2,LANCL2,MIR150,CPTP,GPBP1L1,MIR101-2,CHID1,STAT6,RNF8,CCR7,DDX4,ADRB2,SRSF7,LCORL,MBD3,HAND2,PRDM4,HOXB1,GLRX2,MIR367,MIR600,DKK1,RERE,RPRD1B,OTUD7B,SCAND1,LSM2,MIR9-1,ZNF596,PLD3,LRP3,MIR192,MAP2K3,ZNF7,MIR489,SNAI2,RBM23,GHRL,HNRNPA0,CSNK2A1,CPEB1,PAEP,DHRS7B,HOXC4,SOX9,SART3,NDFIP1,CCR1,IRF8,SAP30L,MIR558,NUCKS1,EIF4EBP2,CD200R1,NR1I2,ING5,PELO,TRIM29,PRPF19,CDC5L,MIR339,MIR147A,PAX9,CER1,JADE1,ZNF790,ZNF473,ZNHIT3,CSRNP3,HSPA8,INTS10,BAG2,MIR1-1,DDX5,NCBP2,MDM2,MIR188,SDCBP,HENMT1,TP53,MIR583,RBM3,UFL1,RBM15B,CDKN1B,TRIM52,TRA2A,FOXJ3,HOMER3,MIR193B,MIR218-2,ZNF326,ZNF526,MIR195,PIWIL1,FAF1,MIR198,HEXB,DROSHA,MIR1249,KPNA2,ZNF692,MIR335,ZBTB14,TRIM15,ZNF189,MIR649,KDM2A,MIR98,GTF2A2,MIR628,PKIA,FGF7,HEXIM2,CDK5,PLAC8,MIR615,MIR624,FCGR2A,PHB1,ING1,MUL1,MIR1298,CX3CL1,ANKRA2,NGRN,FUT8,IRF4,H1-5,CASC3,CLDN3,MIR552,PDCD1LG2,MIR502,H2AB1,MIR214,PPM1D,ZHX3,ZBED4,NLRP3,ZNF655,EID2,RPL6,ILK,TMEM107,MIR301A,NLRP2,MED4,LSM14A,TOP1,TENT5C,SUPT5H,MDFI,CDKN1A,MIR16-2,MIR105-1,ZNF263,NEUROD2,MIR10A,PPARA,PELI1,RXRG,IFNGR1,HAS3,OTX2,JUNB,MIR186,TRIM34,PRL,DMAP1,ENO1,LDLR,GTF2F1,MIR633,RFX5,CSK,ERP29,ZNF267,BTG1,THRAP3,FGR,RNASEL,LDB2,WDR82,ELP6,ANAPC2,CPNE1,CKS2,ECD,MIR21,MIR330,DNM2,CREBL2,SYNCRIP,NGDN,MIR129-1,RBBP9,CD36,BAP1,FOXD3,DXO,TCF21,IREB2,SRSF10,IFI27,MED29,PC,LSM4,RNF128,SMAD4,INO80E,MIR578,UBE2V1,EID2B,MIR1271,MIR938,NOP53,MIR1227,HYAL2,SHLD1,CTNNB1,SP2,H2AC7,KLK5,TSNAX,PDCD10,MAGOH,MIR384,SNX5,DR1,KARS1,NAA16,EIF3D,PSMC3,MIR155,MIR221,SS18,NCOA5,SLC8A1,UBE2N,CARTPT,RRN3,MIR497,GRIA1,LMO4,CREBZF,MIR377,TNFSF13,RIOK2,RLN2,CD14,EIF2AK2,CRY1,DVL2,LACC1,RAB27A,ABCE1,SMCHD1,CD34,DEFB114,MCPH1,JAK2,PTEN,LMO2,FBXL19,MIR500A,MORF4L1,MED31,LRP6,CAND1,USP3,STAT1,MIR148B,TCOF1,PHB2,ZNF175,COMMD6,POLR2G,LEP,SQSTM1,CD200,MIR601,MIR765,SMARCA5,EIF1B,ZNF740,PIWIL3,HOXB8,STK16,MIR873,MIR34B,MED17,MIR7-3,MIR618,MIR563,CCDC3,ZNF319,NTRK3,CIPC,TLR8,MYT1L,MIR296,MIR153-1,EIF4EBP3,EIF2B5,EIF3K,RFXANK,MIR100,MIR625,GTF2IRD1,BRMS1,TRIM3,SEMA7A,TFE3,DRAP1,MIR549A,SRSF4,DNAJB4,NFE2L2,SOX3,MPV17L2,PRMT6,SMARCB1,BMPR1A,RPS7,PKNOX1,NKX3-1,NFKBIL1,CLU,MIR23B,OTULIN,MED30,MACROH2A2,SERPINB1,MIR920,PNRC1,TUSC2,TFRC,ELOC,MAGEB10,PCBD1,NR2F6,CRTC2,TLR5,SFTPD,H2AZ2,CD2AP,CD38,NDP,ZBTB25,GADD45A,FXR2,MIR141,MIR491,SNAI3,TERT,EIF2S1,PABPC1,HCLS1,BMPR1B,TFCP2,PML,MED21,EED,NFIL3,MIR557,TNFSF8,CTDSP2,MIR105-2,PDCD5,SNIP1,CDK1,ATP6AP2,RPS6KA4,MIR194-1,OSR2,DDT,MIR553,MIR126,MYC,MIR184,MIR490,HSPB1,MARS1,MIR142,DAPK1,GPSM3,CASK,MIR106B,SSBP2,LRRC14,DLX1,MIR324,SNRNP70,ZNF687,ZHX1,APOBEC3F,UBE2I,PSEN1,CD4,ZNF397,IRF9,RBM22,SLC38A3,ALKBH5,BRCA1,BUD31,MIR31,SMAD2,MIR342,RAB1A,PIM2,SUPT7L,RBBP8,IFNB1,CAV1,MEPCE,PPP1CB,MTG1,MEAF6,RBFOX2,TNKS,KLK3,MIR152,ZNF177,ZBTB18,MIR147B,TNFSF18,CREBBP,PROX1,WASL,GCLC,DYRK1A,FGF10,IL2RG,IRF6,NCK1,TF,DPY30,KRAS,IL1A,PYM1,LITAF,PICALM,MIR656,TRIM22,AIP,MTF1,FOSL2,LTA,HNRNPC,SETD3,TWIST2,DIRAS3,OAS1,SUMO1,CDCA7L,COPS5,NLRP6,IRF7,MIR425,MIR200C,SMAD1,XPO5,ZBTB26,ZSCAN1,MIR1260B,ACTN4,MIR590,TOMM70,SMG9,DDIT3,POLE3,DNAJC2,MIR586,P2RY1,SRSF1,MIR340,NKAP,FGF22,SIX5,ADORA3,MIR770,ITGA6,UBE2D3,UBP1,CXCL8,MIR133B,FKBP8,EMX1,PPARG,MIR30A,CCDC22,MIR193A,F11R,UFD1,ZNHIT1,PGR,PRKCQ,SLA2,MIR106A,SESN2,EIF4H,MIRLET7G,NFYB,YTHDF2,MIR554,CHRNA7,UPF3B,EZH2,EPO,ZNF664,MIR28,NR4A2,MNAT1,MKKS,MIR422A,EGR1,IL34,IKBKB,GTPBP1,GABPA,HNRNPH3,MIR875,HRAS,PYCARD,BCL7B,HMGB1,SSBP4,RGS2,LBX1,MSX1,CX3CR1,MIR145,ZSCAN5A,NKX6-2,TAGLN3,TRAF1,LY96,POLDIP3,CRLF3,RBBP7,NAA15,MIR505,MIR636,DDRGK1,IL10,FERD3L,MIR640,MIR611,PTGFR,SRSF2,RAF1,ARMCX3,CCR2,F2,PLSCR1,BCL7C,BRD3,PRKCA,ACVR1,EIF4E2,ZBTB45,TRA2B,NFE2L1,BHLHA9,ADNP,CGAS,DAP,ZNF593,INPPL1,USP16,MIR589,CARHSP1,SF3B4,MIR130B,PRNP,DAPK3,MIR607,COPS2,AKT2,PSMA6,MATR3,HMX1,UHMK1,FOXN2,IL6,EFCAB7,AGPAT1,MIR379,TRAF3IP2,SOX21,PYDC2,CD86,PAIP1,LSM5,NKX3-2,G3BP2,MIR223,FCER1G,DDX1,ELF1,FABP4,DNAJC3,IFNA2,MEF2B,CDC73,ADM2,MLLT6,MIRLET7D,MIR196B,TLR9,PLCB1,TNFRSF1B,KCNIP3,MIR580,RPL10,METTL18,SMG8,E2F6,CD80,ANXA4,TAPBP,UCN,GABPB1,GTF2A1,MED27,IKZF2,MAD2L2,SSBP3,NMI,FOXS1,ZBTB33,MIR423,ZNF576,CLEC6A,MIR204,EXOSC8,AGR2,TLR6,SLCO3A1,MTERF2,MIR211,MIR595,EIF4B,PPP3CA,CLP1,ELAVL4,MIR182,ZNF787,IL1B,AKT1,MIR569,DYRK1B,TXN,MAX,GSTP1,RBBP4,TNFAIP3,CCND3,TOX,MXI1,CREB3L4,MT3,INPP5E,NEUROD6,WTAP,CNOT2,ENY2,HMX2,IGF1,MIR604,PTRH2,DKC1,CALR,MIR639,SKIC8,MIR675,GRSF1,TGFBR2,PHF1,HNRNPAB,UBE2D1,MIR631,MIR320A,MIR1251,MET,EIF4A2,KIT,ZNF343,CDK5RAP3,MIR448,TSG101,E4F1,NR1H2,EID1,FASLG,HNRNPA2B1,PIK3CG,IL18,GTF2H2,MIR572,MIR891B,UQCC2,BZW2,ELK3,NEO1,STAU1,PDCD4,MIR139,MIR143,ETV6,MAGOHB,IFT52,CBX7,ISX,NIBAN2,H2AJ,MIR218-1,ELK4,TRUB1,MIR493,CRYM,SETD4,CUL3,NR0B1,MIR24-2,RAN,PIK3R1,NR2E1,MIR30E,MAGED4B,FOXP2,MIR922,SLC38A2,MIR652,CCAR1,MIR874,MIR137,IL15,MIR769,TLR1,MIR532,BCL9,MIR298,MIR455,MIR194-2,MIR208B,INTS12,HDAC6,SGF29,MIR616,MAGEB1,FOXA3,NME2,MED22,MIR592,CCAR2,CREB3,ALKBH4,NR1I3,TMBIM6,CD40,ACVR1B,MED10,TNRC6C,BIRC2,YES1,PRKAB1,HR,ASB1,CD2,NIF3L1,SPTBN1,ATRAID,TCEA1,RNF10,AKAP8L,PTHLH,VIP,STAT5A,VRTN,RNF26,GTDC1,HNRNPDL,CCNH,MRPL13,MRPL12,CYP1B1,RPS13,MIR183,TLR2,MIR16-1,PIH1D1,ZNF575,MIR7-1,MRTO4,H2AC25,WBP2,MAPKAPK5,NUP62,ZNF805,BARX2,RFX4,STOX2,CSF2,BTN2A2,GTF2F2,IL6ST,SRSF12,CCL3,YWHAH,ID1,LILRB1,RTRAF,SFRP1,MAGEH1,RBM12,CSNK1E,PPIA,ZNF322,MIR942,ZNF821,PELP1,MIR7-2,EPHA4,MIR200A,MIR605,DEFB124,MOSPD1,ZNF436,CD46,MIR149,TULP3,CD81,NLRP9,HSPA5,SOCS5,IL20RB,BEND6,NPTN,TAF5L,MYD88,RPS9,TOX4,TYROBP,MIR661,MIR876,FASTKD5,KANSL3,FURIN,MIR760,ZBTB17,MAVS,THAP7,ISG15,UAP1,ZNF345,HCFC2,MIR1226,BHLHE40,ZNF501,MIR30D,MIR517B,MSL2,MIR25,SPP1,DHX9,LTB,TRIM8,TLE1,MIR449B,MIR346,MIR597,RLIM,MIR370,NEDD8,DICER1,TOPORS,ZCCHC7,CNOT6,IGBP1,SF3B5,DLG1,MIR215,BANF1,DNAJB9,IKZF5,SUB1,MIR551B,EXOSC4,IL1R2,STAT2,MIR429,PPP1CC,HDAC5,MIR511,MAP2K1,HGS,PRMT2,STPG4,TOB2,MIR936,ANKRD49,MIR488,MIR29C,ZBED1,TLR7,TSN,BUD23,EDF1,IL5,RGMB,KDM1A,TGIF2LX,KLF4,ZBED3,TLR4,APLNR,ARF4,PCGF2,TRIP4,CRABP2,MIR26B,ZNF574,SAP18,CNOT8,MIR99B,RAP2C,CIAO3,SOST,EPOP,PCGF6,ASCC1,ZC3H7A,SOD2,ZNF362,MIR671,ACTL6B,MAEL,CIAO1,MIR503,MIR212,MLF1,EPCAM,IMPACT,HELLS,PLGRKT,KLHL22,RHOG,SUFU,SUV39H1,MLF2,IFRD2,B2M,RPS26,GTF2I,TCEA2,LHX2,EIF2B2,LUM,ZNF668,MIR638,HINT1,HMCES,C1QTNF1,RNF139,TRIM44,RBCK1,HINFP,ITGB8,FBP1,MIR1296,MED11,EMILIN1,ELAVL2,MZB1,IL1RAP,LURAP1,ZNF511,TCF19,SSU72,HMG20A,SH3BGRL,BCL6,PFDN5,CTDSPL2,HFE,MIR191,CDK8,EDA2R,PDE12,RUVBL1,SHMT1,TNF,MIR9-2,FGF3,TWSG1,HMGA1,ACTB,NAB2,XCL1,RBPJ,SF3B1,BRMS1L,AIF1,FOXC2,NEUROG2,MIR17,GJA1,PAIP2B,CEBPG,RBM38,CNTN1,MIR764,NAB1,PHF12,MIR338,RB1,CITED1,RNF141,TYMS,NFYA,RIOX2,SDR16C5,CDK9,DRGX,NDN,RBM5 |
| 1.104e-06 | -13.72 | Proteasome | pfam domains | PF00227 | 19 | 16 | 17795 | 5224 |
PSMB10,PSMA2,PSMA5,PSMB6,PSMB7,PSMB2,PSMA1,PSMA3,PSMA4,PSMB5,PSMB1,PSMA6,PSMB11,PSMB3,PSMB9,PSMB4 |
| 1.118e-06 | -13.70 | SH3BGRL (SH3 domain binding glutamate rich protein like) | protein interactions | 6451 | 148 | 69 | 19454 | 5460 |
CTTN,RPS3,STUB1,SH3BGRL,ACTB,LGALS3,TMOD3,CFL1,HNRNPC,SLC25A1,IVNS1ABP,MYO6,MECP2,ITGA2,HADHA,ARPC2,SQSTM1,HSPA8,RPS28,NSFL1C,SLC25A3,AKR1A1,STAT6,PPARG,LXN,SDHAF2,TES,CORO1C,IGBP1,DSTN,PSME2,ACSL4,EEF1B2,ELK1,PPIA,RPL7,LYPLAL1,HSPB1,COTL1,AK2,BAG2,HINT1,PRPSAP1,MYO1B,COA4,ARGLU1,SFXN1,PPP1R12A,PRPS1,CAPZA1,RDH11,RPS4X,RPS27A,RUVBL1,VDAC1,ETFA,PSMA1,PSMA5,ZNF397,CD2BP2,MTCH2,LYPLA1,ACTR2,CAPZA2,ARPC3,EZH2,PLS3,TUBB4B,RP9 |
| 1.143e-06 | -13.68 | STX2 (syntaxin 2) | protein interactions | 2054 | 80 | 43 | 19454 | 5460 |
SNAP29,TP53,MRPL11,VAMP2,CTSA,STX12,STX8,BLOC1S2,SNAP23,VAMP8,MOV10,PLPP4,SYT4,STX1A,CDC23,STX5,VTI1B,ANKRD46,SNAP25,STX6,ATG16L1,BET1,SEC22B,SEC22A,CDK7,STXBP1,VAPB,PTP4A2,CPLX2,ENTPD3,PCGF2,STX7,CERS6,VAMP5,ZCCHC12,STX16,PLN,VAMP3,ENO1,MTG1,CYBC1,RMDN3,UBE2I |
| 1.143e-06 | -13.68 | PLD4 (phospholipase D family member 4) | protein interactions | 122618 | 80 | 43 | 19454 | 5460 |
SDF2L1,SERPINH1,CHPF,RAB14,EIF4A2,ABHD12,B4GAT1,PIGK,B4GALT1,GANAB,ATP5PO,HSP90B1,FKBP10,TM9SF1,CHPF2,SEC22B,EMC1,ITGAV,HSPA5,DNAJC3,PDIA3,HM13,PPIB,OS9,SELENON,PTK7,HACD3,STT3A,FAM3A,XXYLT1,CHID1,TFRC,HSPA13,SELENOF,GNAI3,PLD3,NCSTN,ERLEC1,PRDX4,TMED1,ERP29,TMX3,PDIA6 |
| 1.145e-06 | -13.68 | XRCC1 (X-ray repair cross complementing 1) | protein interactions | 7515 | 159 | 73 | 19454 | 5460 |
HSP90AA1,XPOT,TDP1,BRCA1,RBBP8,GCC1,OGG1,BTF3,APEX1,SNRNP40,UBE2I,CSNK2B,ZNF330,PARP2,LIG3,RAN,IRF2,SF3B6,CCNF,CREB1,GTF2IRD1,PPT1,RNF146,LMNA,RPA2,CCL3,MRPL12,ST7,SEC22B,SMC4,NF2,PPIH,PML,RPA3,FOXD3,BRD3,FOXP1,EMX2,H2AC4,CRBN,POLB,XPO1,CSNK2A1,ORC5,OS9,PRNP,TOP1,ARL6IP5,CAND1,RPL35A,SLC39A10,RAP1B,EED,AIFM1,FURIN,SSBP3,NUPR1,APTX,RAD23B,TOPORS,RBPJ,H2BC1,CBX3,SOX2,H2AX,E2F4,TP53,MAX,SSRP1,H3C1,PELI1,PCNA,KLF10 |
| 1.146e-06 | -13.68 | establishment of protein localization to organelle | biological process | GO:0072594 | 345 | 143 | 18204 | 5365 |
SEC61A1,TIMM8A,AIP,NDP,DNLZ,SEC61B,CBL,NUP153,BECN1,NUP50,FIS1,POLA2,H1-5,TRMT10B,VPS54,TIMM23,TOMM20,CSE1L,PEX3,EDEM1,TSG101,SPRN,PML,NUP62,WBP2,CDKN1A,SRPRA,MACROH2A1,TRAM1L1,TOMM40L,KPNA6,LAMP5,TERT,HGS,DRD1,SPCS1,NUP35,TIMM8B,LMNA,CLU,TRIM37,SYK,FAM53B,PEX26,TOMM22,PPP3CA,RANGRF,AIFM1,AKT1,MACROH2A2,UBL4A,VPS28,PEX13,SSR3,SGF29,TIMM10,GRPEL1,TSPAN10,NFKBIA,ROMO1,UBAP1,GRPEL2,ZFAND2A,LRWD1,RANBP6,TNFAIP3,SEC13,SRP14,LAMP3,SEC63,RALA,ING1,RAB11A,TIMM13,MTX2,RAN,TSPO,PIK3R1,SRP72,AGK,TNPO3,SMURF1,FAM53C,HSPA5,SPCS2,TRAM2,TSPAN17,TIMM21,TOMM7,TIMM17A,CACNG3,SGTA,RPL23,PPP1R10,FBXO7,SAMM50,SEC62,KPNA2,SRP54,CHCHD4,PEX5L,TXNIP,TIMM29,MAIP1,SEC61A2,TOMM6,IPO8,RUVBL2,TNPO2,MGARP,TRAM1,HSPD1,HSPA8,PHB2,RPAIN,TOMM70,HIKESHI,HSP90AA1,MTCH2,STK3,SQSTM1,DDIT3,DNAJC19,ZDHHC15,SRPRB,IMMP2L,GNPTG,BCS1L,SEC61G,STK4,PMPCA,TP53,NUP107,SPCS3,KPNA1,TOMM40,RAB8B,BAX,TRAF3IP2,LAMP2,VPS4A,ZFAND2B,ZFAND6 |
| 1.149e-06 | -13.68 | transferase complex, transferring phosphorus-containing groups | cellular component | GO:0061695 | 295 | 124 | 19108 | 5553 |
TCEA1,POLR2B,CDK8,ACVR1B,POLR2L,CCNB1,CDK6,POLR3H,PHKA1,PIK3R2,PARD6A,CDK5,CDK4,PHKG1,SLA2,TERT,CDC73,NRBF2,CDK12,POLR1H,PAAF1,GTF2E1,POLE3,SOCS4,TADA3,ATG101,PYCARD,CKS2,GTF2E2,DAPK1,CISH,SOCS5,SESN2,PRKAB1,SUPT3H,AKAP14,CCNH,SOCS2,CDK1,POLA2,CNPPD1,MNAT1,VAC14,POLR3F,POLR3GL,POLD2,TGFBR2,POLD4,TAF5L,IKBKB,POLE4,TAF11,CSNK2B,CDK9,CCND3,POLR2F,CDK7,CCNY,POLR2C,PIK3CA,RB1,CDK5R1,SOCS3,TAF7,PIK3CG,CDKN2D,GNPTG,POLR2G,CCND1,POLR1B,CDKN1A,RB1CC1,POLR2I,GTF2H4,SKIC8,CCNA2,PRPS1,CSNK2A1,PRIM2,TBK1,GTF2H2,GTF2F1,CAB39,TBC1D5,CCNI,C9orf72,TENT2,PHKB,XRCC5,MCM3,TERC,CKS1B,ERCC3,BECN1,PRPSAP1,POLR1D,GTF2H5,CHRAC1,GTF2F2,GTF2A2,TAF2,PRKAG1,POLR2D,IGF1R,STK11,PIK3R3,PIK3R1,CCNF,ENY2,CCNQ,ACVR1C,TAF9,GTF2B,ACVR1,MAD2L2,AZI2,STRADB,BCCIP,PRKACB,TANK,PCNA,POLR3B,TAF10,GTF2A1 |
| 1.151e-06 | -13.68 | CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1) | protein interactions | 829 | 337 | 135 | 19454 | 5460 |
DLAT,ARPC2,DCTN6,RPA3,DVL2,BAP1,HSPA5,CFTR,CD2AP,NEK2,CDC42,ARHGAP1,SPTBN1,ATG16L1,UBE2M,RPA2,DCTN4,RPS20,SGTA,MSN,PSMA6,CTTN,EIF4A3,CCNF,CREB1,VIRMA,SH3BGRL,SMURF1,RPGRIP1L,DAPK1,PPP1CC,USP14,AR,UBE2H,MAPRE1,UHMK1,BICD2,RC3H2,NLRP9,LIPA,PSME1,RAB1A,NAE1,MDC1,CNOT6L,PSMB10,RNF20,TTC4,HNRNPK,PSMA5,HUWE1,CNOT7,ACTR1A,CCT5,RNF8,NUPR1,ACTR2,CAPZA2,ARPC3,DISC1,TFCP2,PTPN1,CDC5L,CDK9,PRNP,FZR1,ELOC,MPG,HDAC6,PLEKHO1,TSNAX,AKAP1,STK26,DCTN3,DDX5,SF3B1,HSPA8,NMRAL1,DDX39B,STAP1,MCMBP,STAU1,UFL1,ELK4,PPP1CB,PSMB3,WDR77,CNDP2,PIH1D1,EIF4B,CNOT6,DLST,ESR2,PSMB6,TSN,TAX1BP1,ACTB,BAG3,BTF3,CUL3,CUL2,MYC,CDKL2,VMP1,BRCA1,MYO6,CCT2,FAS,ACTR1B,CCT8,ATF3,S100B,PSMD12,TRIM37,TNF,PSMA1,SOX2,ACTN4,NAA15,B3GNT2,CHMP4C,EZH2,PLEKHO2,PHB1,PSMB5,DNM2,DHX15,EGLN3,HNRNPL,CTNNB1,CNOT8,CNOT2,YWHAB,MAGOH,CBL |
| 1.155e-06 | -13.67 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 3164 | 1044 | 18204 | 5365 |
VSTM2A,WNT7A,PPP3CA,SLC45A3,CEBPE,ELAVL4,MIR182,IL1B,TGFB3,AKT1,DYRK1B,TLR6,FUBP3,AGR2,SLCO3A1,RPS4X,IFNA13,SERTAD2,ITGA2,RPL26,CCT7,ENY2,IGF1,NFKBIA,HMX2,ROMO1,DKC1,CALR,SIRT7,MIR675,SNX18,TCF23,TXN,VDR,GSTP1,MAX,GH1,RBBP4,TOX,CCND3,CREB3L4,MT3,TEF,NEUROD6,MET,XBP1,KIT,PID1,FAS,CYTL1,PAK2,MIR130A,IL2,TGFBR2,CCND1,SOD1,AR,HNRNPAB,TAF11,E4F1,PCSK9,NRP1,NR1H2,MIR125A,FGF1,PRKCE,CDK5RAP3,ATF1,RGMA,AKT2,PPP1R12A,ACTL6A,UHMK1,FOXP3,CD274,SF3B4,PAFAH1B2,CLIP3,E2F4,HAX1,PRNP,KLHL25,SMARCE1,TENT4A,ZNF513,MIR223,MMP14,FCER1G,DDX1,UBE2K,ELF1,MOB3B,EFCAB7,IL6,AGPAT1,TOM1L1,ID4,TP53INP1,TRAF3IP2,PADI2,SOX21,MMP9,CD86,IFNA10,PAIP1,MLLT6,ADM2,HDAC3,IFNK,PLCB1,TLR9,SMARCD3,TNFRSF1B,ZNF24,ZBTB16,PPP2R5A,EHD4,LCP2,DNAJC3,MIR96,IFNA2,TNIK,MEF2B,ZNF507,CDC73,RIGI,PAX6,SMYD3,MAD2L2,SSBP3,WNT10B,DSTYK,CLEC6A,CD80,OPTN,GABPB1,UCN,GTF2A1,PRKAG1,TP53INP2,MED27,NLRP1,NR1I3,HILPDA,FGF16,SYK,PITHD1,BOLL,CD40,MED10,ACVR1B,EAF2,PRR5L,NOG,TESC,SGF29,HDAC6,FOXA3,PRDX6,FBXW7,NME2,TRIM5,MED22,STK11,CREB3,APOBEC3C,ALKBH4,VSIR,NIF3L1,CD2,SPTBN1,WEE2,MIR101-1,TCEA1,MED9,TRIM32,TRMT112,UBE2L3,YES1,BIRC2,STAR,LACRT,MED23,LAMP3,PRKAB1,SERTAD1,MRPL12,APOBEC3A,CYP1B1,ZNF287,RARRES2,TLR2,MIR183,AKAP8L,RNF10,VAMP3,PIAS1,DIRAS1,VIP,STAT5A,TBK1,CYRIB,XRCC5,PSMC5,CLEC9A,CCL2,CHCHD2,MAP2K6,IGF2BP1,PDE2A,WBP2,MAPKAPK5,ARL2BP,NUP62,POU1F1,RDH10,MIR16-1,PIH1D1,SERTAD3,RB1CC1,IL18,CSH1,WRAP53,UQCC2,ELK3,CD58,RNF41,CD40LG,TFEB,MIR140,PDE4B,PIK3CG,TAF10,IL17F,APEX1,TCIM,NTF4,SUPT4H1,CACUL1,ROCK1,ETV6,CAMP,KLF1,SETD4,PIK3R2,NR2E1,PIK3R1,OSM,CCL1,NIBAN2,FZD4,CAPN2,TCP1,SOX14,DEK,ELK4,TRUB1,CAMK1,CCNB1,MIR769,IL15,TLR1,BCL9,MTPN,PRELID1,EIF3E,FGF23,SLC38A2,VEGFA,IL23A,MTA2,CCAR1,RFC2,MSL2,HOXB1,SPP1,BTBD10,DKK1,DHX9,ISG15,STAT6,CCR7,UAP1,HCFC2,ZNF345,ADRB2,HAND2,PRDM4,MBD3,C9orf72,PARM1,LRP3,OSBP,MAP2K3,RERE,SESN3,LTB,RPRD1B,TRIM8,SCAND1,TLE1,SUB1,RGN,CSNK2A1,HNRNPA0,HOXC4,PAEP,STAT2,SOX9,BAG3,TOPORS,BECN1,SF3B5,DLG3,CNOT6,RBM23,DNAJB9,TLR7,ZBED1,RGMB,IL5,EDF1,NR1I2,KDM1A,PRPF19,CDC5L,MIR511,MAP2K1,HDAC5,PRMT2,IRF8,HGS,ANKRD49,FCGR1A,NUCKS1,MIF,HNF1B,CCL3,YWHAH,EIF5A2,TPD52L1,LILRB1,BCL10,MIR132,IL12A,BARX2,HEY2,MAP3K12,IRF3,CSF2,RFX4,IL6ST,GTF2F2,KLF12,SETD7,CCL5,RORB,PELP1,EPHA4,TRIM68,TLR3,MOSPD1,DEFB124,AKAP12,DYRK2,RTRAF,IGF1R,SFRP1,FLCN,FERMT2,NUPR1,AGO1,DUSP19,PPIA,IL20RB,HSPA5,MDC1,IL4,NPTN,ILF2,TAF5L,MYD88,FAM98A,CD46,MIR149,MIR146A,DGCR8,CD81,NKRF,NLRP9,ARPP19,TYROBP,GPBP1L1,EEF1E1,FURIN,KANSL3,ZBTB17,MAVS,TADA1,EFNA5,ING2,RUVBL2,STUB1,ORMDL3,TOP2B,FGF7,PLAC8,SH3BGRL,HFE,HINFP,ABHD5,ITGB8,EMILIN1,MED11,GTF2A2,IL1RAP,MZB1,LURAP1,CCT8,TNF,FGF3,ACTB,HMGA1,XCL1,SF3B1,RBPJ,CX3CL1,NGRN,FCGR2A,SLC25A4,AVPR1B,PHB1,ING1,RUVBL1,MID1IP1,MIR17,GJA1,ZBED4,CNTN1,CEBPG,NLRP3,AIF1,FOXC2,IRF4,CLDN3,NEUROG2,MED4,NFYA,SUPT5H,TENT5C,CDKN1A,TMSB4X,CDK9,NDN,TAFAZZIN,RNF152,ILK,CITED1,RB1,SLC25A5,NLRP2,TRIP4,ZNF473,ZNF574,MIR26B,CSRNP3,RAP2C,HSPA8,PTPN1,BAG2,GHR,PAX9,KLF4,ZBED3,APLNR,TLR4,DLG4,ARF4,JADE1,MDM2,MIR188,SDCBP,ACTL6B,TP53,STK4,GNAI3,SOST,LEPR,SOD2,NEK7,NCBP2,CDKN1B,TRIM52,PLGRKT,TRA2A,RHOG,FOXJ3,RBM3,MIR212,UFL1,EPCAM,ZNF668,LUM,HMCES,KPNA2,C1QTNF1,APOC2,TRIM15,TRIM44,B2M,DROSHA,GTF2I,HEXB,LHX2,PRIM2,UBE2V1,LMNA,TNFSF15,PRMT5,SMAD4,TANK,INO80E,PDCD10,RFC3,SNX5,EP300,PACSIN3,KARS1,EIF3D,PIK3R3,NAA16,WDR77,BACH1,SHLD1,HYAL2,CTNNB1,KLK5,GPT,TMEM106A,GRIA1,ODAM,LMO4,TNFSF13,AATF,CREBZF,GNAI2,RLN2,CD14,EIF2AK2,MIR206,MLLT11,MIR221,PSMC3,CDK12,SS18,MSN,CRKL,DIRAS2,CARTPT,TRIM24,RRN3,JAK2,LMO2,MORF4L1,MED31,LRP6,TIRAP,CAND1,STAT1,PKIB,CRY1,GSK3A,DVL2,RAMP3,LACC1,KPNA6,CD34,RAB27A,BAD,JUN,PNP,HAS3,JUNB,OTX2,PRL,TRIM34,VDAC1,DMAP1,HSPD1,ENO1,LDLR,NEUROD2,ZNF263,MTA3,MIR10A,VEGFC,CXXC1,PELI1,PPARA,FLOT1,IFNGR1,RXRG,STOML2,FOXP1,THRAP3,RNF14,IL12B,UBE3A,DUOXA2,RNASEL,POLR3B,LDB2,FGR,GTF2F1,RSAD2,RFX5,ERP29,MIR107,ZNF267,ZFP64,EMP2,MIR548C,MOB3C,DNM2,RGCC,CREBL2,MYBL2,SYNCRIP,DHRS4,LILRA2,ECD,MIR30B,MIR21,MED29,ELK1,LYAR,RBBP9,CD36,MIR210,POLR3F,FOXD3,RMND1,IREB2,POU5F1,TCF21,MIR33B,MIR205,CLU,KLF10,MED30,RALB,RPS7,FCGR2B,PKNOX1,NKX3-1,ATF3,STAP1,ATG16L1,PCBD1,CSRNP1,ISCU,MIR24-1,CRTC2,SMAD3,KMT5B,RAP1A,EIF4A3,WNT2,HNRNPD,TAF9,TUSC2,TFRC,SELENOK,TRIM62,NEK2,CD38,TICAM2,NDP,FXR2,TRAF6,GADD45A,TLR5,CCL19,PLAGL1,TMEM59,RNF40,HCLS1,FOS,CHI3L1,BMPR1B,IRF2BPL,TFCP2,NFKB1,TERT,TESK1,ARG2,HLF,SUPT3H,PLP1,PABPC1,LIPT2,NRDE2,PTGES3,SMARCA5,ZNF609,ANGPT1,SH3BP4,SRC,ZNF175,PHB2,POLR2G,SQSTM1,HNRNPK,LEP,TRIM21,CD200,ATF4,MED17,TAB2,IFNG,MEF2A,STK16,TOM1,AFAP1L2,UTP15,PQBP1,IRF1,STARD4,NTRK2,LMO3,CCT5,NTRK3,ZNF319,IFI16,TLR8,NBN,EIF2B5,METTL14,ACTR2,RFXANK,FBXO7,SOX3,NFE2L2,TICAM1,AKR1C1,MPV17L2,SMAD9,SMARCB1,MECP2,BMPR1A,TFE3,SEMA7A,BMPR2,EXOSC3,MIR29A,BNIP3L,PTPN22,SOX2,NFKBIB,WASL,TRIM37,IRF2,RAP2B,DYRK1A,ABHD14B,PXYLP1,SNX33,KLK3,CDH13,PIWIL2,GREM1,ZBTB18,MTDH,ADTRP,PROX1,TNFSF18,CREBBP,ACTA2,DPY30,KRAS,NOTCH2,SVIP,SRPK2,RASL11A,MIR144,CHP1,TGFB2,IL1A,PCNA,FGF10,IRF6,IL2RG,NCK1,TF,ZBTB38,CCL21,TADA3,NFE2,CIRBP,TRIM22,AIP,BAZ1B,MTF1,PYM1,CDK7,PICALM,LITAF,MAFG,IRF7,MMD,CCT2,SMAD1,MACROH2A1,RIT2,ACTN4,CTBP1,PRKCB,SHC1,LTA,FOSL2,PAGR1,HNRNPC,OAS1,SETD3,TRAF3IP3,COPS5,PSRC1,CD83,PDCD5,SASH3,ATP6AP2,APLN,CDK1,OSR2,RPS6KA4,HTR2A,DDT,INPP5K,MED21,NFIL3,HSP90AA1,SMAD5,TNFSF8,WDR45,SPON1,GPSM3,G3BP1,CASK,DLX1,WWP2,SSBP2,HNRNPA1,FRMD8,CREB1,MYC,HSPB1,MARS1,DAPK1,IFNAR1,RUNX1,ZMPSTE24,IRF9,RBM22,IFIH1,SLC38A3,BRCA1,BUD31,TAF2,SMAD2,SNRNP70,MIR324,APOBEC3F,ZGLP1,EGR2,TNKS2,PSEN1,RPS27L,CD4,HBEGF,CAV1,IFNB1,MEPCE,MEAF6,TNKS,TAB1,HSP90AB1,AGAP2,CBFB,CD28,RAB1A,PIM2,SUPT7L,MSTN,MEF2C,HMGB1,YTHDF1,SSBP4,ZNF770,INO80C,EPHA2,S100A10,CAB39,GABPA,LARP4B,BATF,PLEKHF1,AGER,ZNF304,PYCARD,MIR23A,HRAS,CRLF3,ADIPOQ,POLDIP3,NAA15,LBH,FGF17,RBBP7,DDRGK1,MAP3K11,H2AZ1,YAF2,MIR640,IL10,ROCK2,PTGFR,ARMCX3,RAF1,MSX1,CX3CR1,TRAF2,MIR145,NMBR,RFC5,EEF2,RPS3,LY96,TRIM6,DDR1,BRD3,TFDP2,ACVR1,LDB1,CCR2,F2,POMT2,PIP4K2C,PLSCR1,MIR657,HSPB8,ZNF593,PSMD10,TNFRSF14,CXCL10,USP16,ZNF622,SH3GLB1,SPHK2,RFC4,FBXW11,TRA2B,ADNP,TRIM23,STRADB,OGG1,CGAS,HELT,P2RY1,FGFR1,SRSF1,VGLL2,SCAMP5,SIX5,FGF22,ACSS2,ADORA1,PTPN11,TOMM70,TRIM27,DDIT3,DNAJC2,CDK6,TFPT,GHITM,CXCL8,TAF7,DIPK2A,CCNY,TENT5D,SPPL3,IDO1,CLEC7A,IL21,KCTD20,ITGA6,VPS72,MITF,IL13,ATG101,UBP1,MIR34A,RAP2A,RNF20,TSPO,PGR,FAXDC2,ZNHIT1,JUP,GPNMB,PRKCQ,RNF187,SESN2,MIR106A,PPARG,SP1,SFRP4,RPL23,CCNA2,PTGER4,SLC6A4,EPO,NR4A2,RAD21,CNOT7,GAPDH,EGR1,CHCHD4,TGFB1I1,IKBKB,MYRF,IL34,NCSTN,NFYB,YTHDF2,ESR2,CHRNA7,EZH2,IER2,IL3,UPF3B,ITK,IL7,RFXAP,EZH1 |
| 1.158e-06 | -13.67 | ARNT (aryl hydrocarbon receptor nuclear translocator) | protein interactions | 405 | 232 | 99 | 19454 | 5460 |
BRCA1,HSP90AA1,ICAM1,SP1,RPS5,MYC,SFN,CUL2,PCCB,MATR3,SNRNP40,MAD2L1,RPL19,ESR2,VEGFA,NFKBIA,GTF2F1,GTF2F2,FEM1A,MYL6,SHMT1,HSPA8,EP300,SMAD9,TNNC2,HSPB1,CIAO3,CTNNB1,RPL7,EGLN3,NUP35,DNM2,S100A8,RPL18,RAF1,RANBP1,H1-3,JUN,SOX2,PPP2R1A,KRAS,RUVBL1,ASF1A,IRAK4,CYP1B1,HSPD1,CDKN2C,MYO1B,RUVBL2,BAG2,EPHA2,STK11,SLX1A,AKT1,SMARCA5,GMNN,KPNA6,NONO,AR,LDHA,GNAI2,CREB1,CTTN,HEY2,UBE2I,JUP,SPTBN1,NF2,HMGB1,RPL4,LSM8,RPA3,RPL27,PML,RTN4,ARPC2,TNFAIP1,BECN1,KPNA1,CSNK2A1,ELOC,RPL35A,CAND1,FZR1,TMPO,CDK9,PTP4A3,AIP,RB1,CDK6,STRBP,MTA3,TP53,CDK4,MAP2K3,TIMM8A,PTGES3,SLC25A11,HAPSTR1 |
| 1.163e-06 | -13.66 | SSR3 (signal sequence receptor subunit 3) | protein interactions | 6747 | 140 | 66 | 19454 | 5460 |
RPLP2,LDLR,PCBP4,PHB1,COX4I1,SSR2,COQ8A,EGLN3,RBM42,ERLIN1,NDNF,FZR1,RPS16,ATP5MG,DRG1,AQP2,RPL10A,RB1CC1,HAPSTR1,SEPTIN7,BCKDK,CYP2C9,PSEN1,VDAC1,ASPM,DDX39A,FAM162A,CCDC47,RAF1,SRP72,CHMP4C,RPN1,EZH2,SEC61B,SEC61A1,LMBR1L,PSPC1,UQCRC2,VDAC2,VIRMA,ESR2,PRRC2A,TCEAL1,PDE4B,HNRNPC,OST4,MAPRE1,HSP90AA1,EPHA2,CHORDC1,RTN4,SQSTM1,RABAC1,SF3B1,DDX39B,RPA3,SAP18,FBXW7,HSCB,YIPF5,PGRMC1,TOMM22,SCLT1,GRM2,SSR1,RPA2 |
| 1.167e-06 | -13.66 | GLP1R (glucagon like peptide 1 receptor) | protein interactions | 2740 | 116 | 57 | 19454 | 5460 |
MFSD5,LAPTM4A,COMT,CD63,IER3,OCIAD2,CYSTM1,AIG1,CAV1,PPIB,CD81,TMBIM6,RAB5C,DHRS7,STOML2,ATP6V0B,ERP29,TMEM147,SPTSSA,MRPL22,TOMM6,EMP2,GJB1,APH1A,NRGN,MTCH2,SELENOK,SYNGR3,POMT2,SERPINA1,RTRAF,AP2M1,TMEM176B,GPR37,CELA3B,ATP6AP2,ATP5F1A,SYNGR4,OST4,CNIH4,ATP5MC3,RTN4,DAD1,SVOP,SLC37A4,FTL,RNF5,NUCKS1,CCDC167,PGRMC1,SUMO1,CEND1,ELOVL1,MYL6,FDFT1,VAPB,SYS1 |
| 1.171e-06 | -13.66 | MAGEB2 (MAGE family member B2) | protein interactions | 4113 | 346 | 138 | 19454 | 5460 |
SRPK2,RSL24D1,RPL10L,CSNK2B,PRKRA,RBMX2,SRP54,MACROH2A1,PSPC1,CDKN2AIP,PPIG,RPL26,RPF2,SMARCA5,RPL7A,UTP23,AATF,BRIX1,HDAC3,RPS15,DGCR8,RPL4,RBM23,RPL27,PML,NLE1,RPLP0,RPL26L1,TFB1M,ZNF574,ZNF770,ZCCHC17,CFTR,RPS14,ATG16L1,PIP5K1A,DKC1,NOP9,SURF6,RPS16,RPL35A,TOP1,PWP2,RPL12,KRR1,CDK12,NOL12,RPS2,RPL10A,MPHOSPH10,CSNK2A1,MOV10,CMSS1,SPATS2L,SRSF12,PSEN1,RPS13,EGR1,RPL17,PAK1IP1,IMP4,RPL3,RPL23A,DHX9,NKRF,SRP72,RBM34,TAF1D,H2AX,FCF1,RPL15,STRBP,IMP3,SRFBP1,TP53,RPL10,RPL19,RPL7L1,RPF1,RPL35,RPL37A,PRMT5,RPS9,ZNF22,RPS26,NSA2,FAS,MRPS25,DCAF4,BRCA1,FTSJ3,NOA1,ZNF668,MYC,SFN,NOP16,UFL1,HSCB,NOP53,STAU1,RAB5A,NKAPD1,LXN,DET1,RPL27A,RPS10,RPL7,LYAR,RPLP1,HP1BP3,RPLP2,RPL8,RPL9,PHB1,MYEF2,SRSF1,RSBN1L,DCAF11,ZCCHC9,DROSHA,DDRGK1,DDX50,WWP2,RPL6,RIOX2,RPL28,MAGEC2,ZBED1,H1-6,RPS24,SRSF8,RPL31,ZRANB2,RPS11,RPS23,RPL18,MAK16,TRMT1L |
| 1.177e-06 | -13.65 | SURF1 (SURF1 cytochrome c oxidase assembly factor) | protein interactions | 6834 | 184 | 82 | 19454 | 5460 |
PDE12,TNFSF8,USP30,KGD4,ETFA,EDEM2,MRPS17,FLOT1,FKBP8,PTGES3,ATP5PF,MRPS18B,CLPB,NUDT19,NDUFS3,AQP3,NDUFS6,NEFL,NDUFA12,MRPL49,ATP5PB,NDUFA2,ETFB,PPIF,MGARP,MRPL50,NDUFS8,ATP5PD,RAMP3,PNPLA8,MRPS23,MRPS9,PHB1,COX4I1,HSD11B1,FKBP4,HAX1,MRPS26,NDUFB8,MOV10,GRSF1,STOML2,COX5A,MRPS35,NDUFV2,NDUFS2,NME4,PHB2,MRPS7,MRPL20,DLAT,MRPS34,COX6C,SAMM50,NDUFA5,CYC1,PTAR1,MTX2,TIMMDC1,HCST,UQCRC1,TIMM13,NDUFAF3,MRPL12,ATP5F1B,SLC25A4,CHCHD3,ESR2,NDUFAF4,TACO1,DLST,MRPS28,PTPMT1,CHCHD6,SYP,MRPS25,CHCHD4,NDUFB10,NDUFAF2,COX6B1,PYCR2,PYCR1 |
| 1.177e-06 | -13.65 | MRPS16 (mitochondrial ribosomal protein S16) | protein interactions | 51021 | 184 | 82 | 19454 | 5460 |
PSMA5,MRPL22,MRPS17,FASTKD5,MRPS18C,MEPCE,IMMP2L,HNRNPDL,SLC25A5,HSPD1,MRPS18B,HINT2,COX8A,MRPS11,PDHA1,GFM2,FAM136A,OTULIN,MRPL11,APOBEC3D,AURKAIP1,SOX2,METTL15,FZR1,CAND1,ATXN10,RMND1,SURF6,MRPS23,MRPS9,SSBP1,COQ8A,ALYREF,PRR3,TRMT10B,GATD3,RHOG,PSMD7,CHCHD1,SNRNP70,TMEM70,MRPS26,USP15,MTRF1,GRSF1,DDRGK1,UFL1,HSCB,FBXW7,PSMC1,CRYZ,AATF,NGRN,BAP1,EXD2,NOG,FAM50B,GFM1,MRPS34,ZNF574,HEXIM1,MTRES1,KLF4,MPV17,TIMM29,KLF12,RPL10,TACO1,CCNF,MTG1,CCDC90B,MRPS25,MCAT,DNAJC19,RIT1,MYC,AUH,MTG2,PMPCA,CUL3,RPL7A,TUFM |
| 1.187e-06 | -13.64 | PARL (presenilin associated rhomboid like) | protein interactions | 55486 | 215 | 93 | 19454 | 5460 |
MTX2,TIMM10,NDUFAF3,TIMM29,TIMM13,NDUFA5,PHB2,HSCB,NDUFS2,MRPS7,TACR3,PYCR1,COX6B1,CMC1,TACO1,CD79B,NDUFAF4,CHCHD3,SOX2,NDUFS6,NDUFA12,FAM136A,CHST10,NDUFB5,PREPL,MRPS11,HINT2,OPA3,CA10,IMMP2L,MRPS35,PDIA3,NDUFV2,AK2,NDUFB8,HAX1,UQCC6,MRPS26,PHB1,OCIAD2,NDUFS8,EGLN3,RAMP3,TIMMDC1,RBFOX2,SAMM50,COX6C,CYC1,PHYHIP,TMEM126B,GFM1,SLC25A51,CLEC12B,NME4,SLC7A1,POLDIP2,GRPEL1,PYCR2,NDUFB10,NDUFAF2,SYP,PTPMT1,CHCHD6,NDUFA2,RAP1A,FAM162A,TMEM126A,ATP5PB,TIMM8A,PPIF,APOO,NDUFS3,COX19,ACADSB,GPD2,SLC25A24,ITGB8,SFXN1,CLPB,HSPE1,DNAJC30,CD80,COX5A,SMIM12,CCDC92,SLC2A1,COX4I1,AIFM1,TIMM8B,EEF2KMT,PLGRKT,SLC25A12,TOMM70 |
| 1.190e-06 | -13.64 | STRN (striatin) | protein interactions | 6801 | 132 | 63 | 19454 | 5460 |
ISCA2,FGFR1OP2,CCHCR1,CCT2,STK24,BRCA1,ENDOD1,PSMC5,RMDN3,MOB4,PLP1,CTTN,CTTNBP2NL,VIRMA,ESR2,DYNLL1,ATG16L1,EEF1E1,TMOD1,TFIP11,RPA2,GOLGA5,RTN4,STK26,EP300,DVL2,RPA3,PML,PPP2R2C,SNX24,CSNK2A1,EXOC1,STK4,PRPF19,PSMD3,MAP1S,PDCD10,DDX1,HSPB1,USP15,SMAD4,TNIK,PPP2CB,TRAF3IP3,SLMAP,CCT7,CAV1,STK3,EIF2S1,TCP1,PRNP,PPP2R1A,TULP3,CCT5,SF3B5,BAG2,TFPT,CTTNBP2,SIKE1,CCT8,RINT1,PSMA5,CAMK2G |
| 1.190e-06 | -13.64 | PYHIN1 (pyrin and HIN domain family member 1) | protein interactions | 149628 | 358 | 142 | 19454 | 5460 |
WDR83,GTF3C4,CHMP1A,ZNF326,MRPS34,MACROH2A2,LUC7L3,WTAP,TFIP11,PML,PRPF4,NBN,PPM1G,EXOSC4,LSM12,PGK1,TWNK,RPL4,EIF5B,AATF,BRIX1,EIF4E,ZNF687,RPL7A,SMARCA5,MECP2,NRP1,UBN1,LIG3,SF3B6,PELP1,MACROH2A1,CSNK2B,ZNF622,MAGOHB,SRPK2,TECR,MRPL47,TP53,STRBP,IKZF5,ZMYM4,WBP11,H2AX,ADAMTS1,LLPH,SRP72,NKRF,TCOF1,MAP1B,MRPS18B,SLC16A1,RPL23A,CDC40,HUWE1,MDC1,MEPCE,MOV10,TMA16,MPHOSPH10,SNRNP70,DNAJC7,RPS2,SRP14,H2AZ1,CWC15,MDM2,TMPO,ZC3H14,DUSP14,ZNF428,GPC4,PSMB7,SDC2,NCOA5,XRCC5,SLU7,HIRA,CCDC86,NOP53,GPC1,LYG2,G3BP2,MRPS7,CUL3,NOP16,MCM4,RPS29,CPSF2,RIOK2,H1-10,FBXW11,PARP2,SNRPD1,ZMYM2,RPL7L1,LGALS3,RPL19,RPL10,CBX5,SUPT5H,RANBP1,RPL29,PLS3,GTPBP1,SART3,MTA2,TOP2B,ABCF1,RPS24,SATB1,TRIM26,RBBP7,DHX16,SSRP1,RFC2,GTF3C3,SRSF4,RPL6,BAZ1B,DDX50,EIF3D,YWHAH,YWHAG,SKIC8,WDR12,DICER1,SDC4,MRTO4,MYEF2,FUBP3,RPL8,RPL9,HP1BP3,RPL7,CCAR2,LYAR,NOB1,RPS10,HNRNPL,SRSF10,CACYBP |
| 1.192e-06 | -13.64 | RNF5 (ring finger protein 5) | protein interactions | 6048 | 124 | 60 | 19454 | 5460 |
CCDC47,INSIG2,YIPF4,UBE2V1,ERLIN2,RUSF1,TMED1,EPHA4,TMEM33,SRPRB,LEPROTL1,PLPP6,SELENOS,SLC38A7,UBE2E2,EDEM1,YWHAH,TMBIM6,ORMDL3,FAM241B,UBE2D1,RNF139,DNAJC7,UBE2N,UBE2G2,S100A8,TYMS,DERL2,EGLN3,ERLIN1,UBE2W,TMUB2,SEC22A,PLP2,ETF1,CFTR,IDH2,JKAMP,GPR35,RABAC1,SYVN1,DERL1,MAVS,UBE2K,UBE2D3,RNF5,ADRB2,TMUB1,TNFAIP3,ARL6IP6,TOMM40,UBE2E3,CYB561,CA2,CCNF,LMBR1L,SLC1A1,CTSB,RBBP4,UBTD1 |
| 1.194e-06 | -13.64 | RTN1 (reticulon 1) | protein interactions | 6252 | 103 | 52 | 19454 | 5460 |
DYRK2,UTP15,LMNA,SDCBP,SSR1,FGFR1,SIGMAR1,OTULINL,SEC62,PXMP2,STX7,CCR4,WDR3,ADRB2,SYVN1,RAB5A,DERL1,EMG1,RTN4,RAB9A,TOMM40,SMARCA5,HNRNPC,DES,GSK3A,SEC61B,MACROH2A1,LMBR1L,SCAMP2,CHRM5,CYB5R3,UGCG,STIM1,SSRP1,RAB3B,ZYX,PLSCR1,TMT1A,BCL2L1,TMEM70,ESYT1,FAM241A,TMPO,FHIP1B,ARL6IP5,PLEKHF2,PRNP,DERL2,HSD17B11,TYMS,RAP1B,PTPN1 |
| 1.196e-06 | -13.64 | PLD3 (phospholipase D family member 3) | protein interactions | 23646 | 235 | 100 | 19454 | 5460 |
SLITRK5,SPP1,ESYT1,AGPAT1,DPP4,NFKB1,FAM20C,COPS5,DNAJC1,PRNP,LMAN1,CAV1,SRPRA,HRAS,HACD3,HSD17B11,GPD2,SURF4,LBR,ERLEC1,TOLLIP,ATP2B4,DNAJC10,STK11,UBE2H,NPTX1,DNAJC5,ARMC6,SEC63,CCNF,SCAMP2,GANAB,LMNA,RPA2,WWP1,HSP90B1,GPR35,TM9SF1,HNRNPH3,LEMD3,CHPF2,CFTR,CYB5D2,RPA3,RHOU,HNRNPH2,EGFL7,RTN4,TMEM30A,BCL2L1,PDIA3,SLC38A7,HNRNPL,SELENON,PGS1,OS9,PSME2,PTK7,MPDU1,PHB1,DIPK2A,GJA1,STIM1,RPN1,TUBB4B,PLD3,HGS,RAF1,DNAJC25,NCSTN,KRAS,TMT1A,PDIA6,MYC,CUL3,OPRM1,SLC1A3,EIF4A2,PPP5C,ABHD12,ESR2,ALG5,LMBR1L,PIGK,SEC61B,SMCO4,LMBRD2,PPT1,ANXA7,FDFT1,CNPY3,OTULINL,SEC62,EDEM3,EMC1,ITGAV,DNAJC3,TMEM106B,RAB5A,ARRDC3 |
| 1.198e-06 | -13.63 | activation of innate immune response | biological process | GO:0002218 | 171 | 80 | 18204 | 5365 |
TBK1,KLRD1,XRCC5,MAPKAPK3,TMEM126A,BECN1,IFI16,TLR8,LILRA2,PAK2,TLR5,TIFA,TLR2,PQBP1,CD14,NLRP3,TRAF6,MYD88,TICAM2,TLR10,IRAK4,TLR9,IFIH1,CGAS,ATAT1,OAS1,TRAF3IP3,LACC1,PRKCE,KCNJ8,CLEC6A,IKBKB,MAVS,TIRAP,NMI,MAP2K6,TLR1,TYROBP,TLR7,IRF7,RIGI,TICAM1,SIN3A,NLRP6,LSM14A,PSPC1,NONO,RNF34,PYCARD,CREBBP,TLR4,TRIM5,HEXIM1,PHB2,TOMM70,IRF3,TLR6,HSP90AA1,HSPD1,BCL10,SRC,CD274,OTULIN,MATR3,SYK,HMGB1,NLRP1,MBL2,PHB1,LY96,TNFAIP3,KLRC2,CLEC7A,PIK3AP1,TLR3,CLPB,FCN2,NFKBIA,EP300,TNF |
| 1.202e-06 | -13.63 | SMN1 (survival of motor neuron 1, telomeric) | protein interactions | 6606 | 293 | 120 | 19454 | 5460 |
MED31,EHHADH,WDR77,COIL,RAB5A,JADE1,DDX5,NMRAL1,SNRPA,RIT1,CHTOP,MYO6,SNRPB,PRPF31,CUL3,ESR2,RPL10,ERH,SNRPB2,LRIF1,RBBP4,ACTB,ATP5F1B,PRMT5,SNRPD2,SNRPD1,CCDC90B,BAD,SNRPE,HDAC11,CHMP4C,PDHA1,EZH2,LSM10,NRN1,TULP3,TUBA1A,RAF1,ARFGAP1,B3GNT2,DMPK,ZBTB16,KRAS,EWSR1,HNRNPA2B1,HSPB1,DICER1,TERC,TRAF6,IKBKB,DDRGK1,ACTL6B,HNRNPA1,XPO1,RPL6,SELENOW,EGLN3,RPL7,SNRPA1,SNRPD3,SUMO3,MPP1,NOP58,ATP6V1A,SIN3A,AGAP1,HNRNPH3,CARHSP1,LSM2,RBFOX2,VPS28,ADAMTS10,KDM1A,SQSTM1,RPA3,BAP1,UBE2H,PPIG,GEMIN8,LSM6,NEURL2,EIF3G,TUSC1,NONO,NTAQ1,TIA1,C9orf72,DDAH2,SRP54,TMSB4X,POP7,CCNF,PSPC1,INPP5K,SULT1A3,GEMIN7,HBP1,PPP4C,EEF1A1,TP53,UBL4A,MDC1,SMN1,SNRPG,THRAP3,LSM4,DYNC1I1,DHX9,PSME1,USP15,RPS2,SNRNP70,GAPDH,TLE1,FAM20C,FNDC11,CDC5L,NKIRAS2,TMPO,SYNCRIP |
| 1.205e-06 | -13.63 | HSD3B7 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7) | protein interactions | 80270 | 385 | 151 | 19454 | 5460 |
RETREG1,SAR1B,SLC35A2,NUP42,SEMA4C,KRAS,EMC8,USP30,SCD5,RINT1,TMEM87A,PLD3,VAMP2,STIM1,NUDT19,RPN1,FAF2,NUDCD3,YIPF3,ARFGEF1,STBD1,MACO1,NUP35,SLMAP,STX5,CYB5A,GJA1,FUBP3,LRRC57,C2CD2L,AGR2,CDK5RAP3,DDRGK1,SLC38A9,YTHDF1,GOSR1,BET1L,EMG1,APPBP2,ZBTB42,FDFT1,ARCN1,VAPB,TMEM115,RAB6A,OTULINL,SEC62,BET1,NOTCH2,GOSR2,PGRMC1,TOR1AIP2,TOMM22,ATP6AP2,REEP4,ATP5F1B,GPR89A,GGT7,CYB5R3,ARF1,ZMPSTE24,VMP1,SCFD1,ICAM1,LMNB1,SLC30A5,RAB11A,VEZT,FKBP8,SLC6A8,SRPRB,ANAPC11,RHBDD3,TMX3,YIF1A,STX18,STX8,RAB1A,RUSF1,NSDHL,OTX2,TMEM31,TFRC,LBR,UBIAD1,YTHDF2,SNAP29,PREB,CCDC47,CAV1,LMAN1,TMPO,SLC38A2,DNAJC1,ARL6IP5,CDCA3,COMT,CAMLG,PTPN1,SRPRA,OSBPL8,BTN2A2,AGPAT1,NUS1,SMIM12,ESYT1,POR,RAB23,HM13,DHRS7,EI24,MOV10,TMEM199,TMEM209,YKT6,CERS2,SLC7A1,SPCS2,MTDH,EGFL7,RTN4,MAVS,TMX2,TEX264,LEMD3,ACACA,SSR1,USE1,STOM,GOLGA5,TMX4,SLC12A2,UBA52,ARHGAP1,SEC22B,RABL3,SEC63,VKORC1L1,SC5D,ZNF655,ELOVL4,ATL1,VAMP3,CDIPT,SNX5,ATP1A1,ARFGAP3,MGAT5B,HMOX2,GORASP2,DEPDC1B |
| 1.211e-06 | -13.62 | regulation of innate immune response | biological process | GO:0045088 | 449 | 179 | 18204 | 5365 |
SFN,MIR149,LILRA2,MIR146A,MIR21,RTN4,GFI1,IFNK,TLR9,IFIH1,SH2D1A,MYD88,TAX1BP1,CD36,POLR3F,LYPLAL1,TYROBP,RIGI,SIN3A,CPTP,CAV1,IFNB1,TRIM11,LYAR,NMI,SERPINB9,CLEC6A,TAB1,MAVS,USP15,IRF3,HSP90AA1,PELI1,RNF34,FLOT1,MATR3,LILRB1,BCL10,HSPD1,IL12A,CD274,RSAD2,USP38,PYDC2,CCL5,LRRC14,IL12B,TLR3,POLR3B,FGR,UBE2K,PAK2,BECN1,IFI35,KLRD1,BANF1,MIR20A,STAT2,EIF2AK2,FAM3A,CD14,PRKCE,LACC1,OAS1,TRAF3IP3,TLR7,IRF7,NLRP6,MIR200C,MIR708,PLA2G5,TIRAP,NR1H2,ISG15,TLR6,NCR3,HCFC2,CREBBP,PTPN22,AKT1,TRAFD1,NOP53,DHX9,TNFAIP3,NFKBIA,EP300,CLPB,FCN2,PPARG,SLC15A2,IFI16,TLR8,CSNK1A1,BPIFB1,ZNRF1,UFD1,PIK3R1,IRAK4,YWHAZ,PQBP1,TRIM3,IRF1,YTHDF2,RNF115,SAMHD1,ATAT1,TICAM1,NFE2L2,TLR1,CNOT7,TRIM15,IKBKB,PTPN11,HEXIM1,PHB2,TOMM70,TLR4,SQSTM1,LEP,NONO,TRIM21,MIR140,SEC14L1,NECTIN2,HSPA8,PTPN1,SRC,CLEC7A,IL21,LGR4,NEK7,TLR5,IRF4,TIFA,MAPKAPK3,NINJ1,TMEM126A,TBK1,PLSCR1,XRCC5,MIR17,CLEC12B,TICAM2,TLR10,TLR2,NLRP3,EIF4E2,TRAF6,KCNJ8,CGAS,LSM14A,PSPC1,MAP2K6,TASL,S100A8,FCGR2B,NFKBIL1,TRIM5,CD226,DUSP10,PYCARD,NLRP1,ABHD17A,MBL2,CD1D,SYK,HMGB1,OTULIN,PIK3AP1,TRIM32,KLRC2,PHB1,BIRC2,TRIM6,LY96,TRIM62,TNF,SARM1,MUL1 |
| 1.232e-06 | -13.61 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | REACTOME pathways | R-HSA-163200 | 113 | 60 | 10285 | 3229 |
COX14,UQCRC1,COX6B1,NDUFB6,TMEM126B,SLC25A27,ATP5PD,ETFB,UQCR11,UQCRQ,NDUFC2,NDUFA4,COX16,ATP5PO,ATP5PB,ATP5MG,SDHC,COX20,UQCRC2,NDUFAF2,ATP5F1D,COX5A,NDUFV2,NDUFA5,ATP5F1A,COX4I1,TACO1,ATP5F1E,ATP5F1B,NDUFB4,NDUFS6,NDUFA2,NDUFAF6,NDUFAF4,COX7B,UCP2,COQ10B,NDUFA12,NDUFS8,NDUFAB1,ATP5MC3,NDUFA1,NDUFS3,SDHB,TIMMDC1,COX6C,NDUFAF3,NDUFS2,COX8A,CYC1,NDUFB10,NDUFB7,SLC25A14,COX11,ATP5MC1,UQCRH,ETFA,NDUFB8,ATP5PF,NDUFB5 |
| 1.236e-06 | -13.60 | MRPS34 (mitochondrial ribosomal protein S34) | protein interactions | 65993 | 299 | 122 | 19454 | 5460 |
MRPS28,MRPS21,TUFM,MRPS16,UBE2H,PSMG3,DNAJC19,IGF2BP1,BAP1,GFM1,SQSTM1,PSMG4,SLC25A51,MRPL41,HMGB1,RPL4,AATF,CRYZ,RBMS2,KLF12,RPA2,ZNF770,MTRES1,KLF4,HEXIM1,RPL26L1,ZNF574,COX4I1,ALYREF,MRPS9,SSBP1,SYNCRIP,SRP14,TRMT10B,PRR3,CGAS,CAND1,FZR1,ZBTB2,MRPS23,DKC1,GRSF1,MOV10,TMEM70,SNRNP70,CHCHD1,TUBG1,USP15,DLG1,MRPS18B,CLPB,DNAJC30,H3C1,MRPS33,MEPCE,MRPS18C,FASTKD5,MRPL11,CDK4,STRBP,METTL15,AURKAIP1,APOBEC3D,GFM2,CIBAR1,ILF2,MTG1,CCDC90B,TACO1,RPS9,RPL35,RPL10,ESR2,PRRC2A,CUL3,PMPCA,MTG2,MYC,AUH,MRPS25,NOA1,FBXW11,PSKH1,MCAT,H1-1,PDF,EXD2,NGRN,NOP53,HSCB,UFL1,MRPS7,TIMM29,PHB1,GATD3,HNRNPL,RMND1,RPL6,MRPS35,MTRF1,DDRGK1,RHOG,LHX2,POU5F1,MRPS26,HSPD1,SLC25A5,PREPL,COX8A,SRSF7,MRPS11,HINT2,HECTD3,KRAS,IMMP2L,MRPS17,SOX2,CHMP4C,PDHA1,NFKBIL1,SKA3,MTA2 |
| 1.244e-06 | -13.60 | RABGEF1 (RAB guanine nucleotide exchange factor 1) | protein interactions | 27342 | 187 | 83 | 19454 | 5460 |
VTI1B,CAND1,TRIM15,THOC1,KCTD10,SLMAP,HSP90AB1,NUF2,CAV1,HMG20A,HRAS,RPRD1A,NRSN1,EED,CRBN,UBE2D1,TRAPPC2L,HNRNPD,CBL,YWHAB,ATG9A,KXD1,RAB5C,GPRASP2,YWHAH,SNAP91,INSYN1,YWHAG,RAB22A,EXOC1,ARL5B,L1CAM,ROCK2,RBCK1,RPS27A,TFPT,CIPC,SLC39A7,CPNE2,SLC39A3,DHX9,IGF1R,EZH2,TMEM31,RAB4A,MAX,B3GNT2,TRAF2,SNAPIN,TRIM54,TAX1BP1,B4GALT3,UBB,SESTD1,ARF1,CCNF,PSMA6,TMEM74,PHF21A,CHRAC1,YWHAZ,CCHCR1,RAB2A,EMILIN1,SFN,RAB11A,SLC30A5,DNAJC5,UBE2D3,OIP5,RNF11,SLC39A9,BIRC2,RAB5A,EP300,ARRDC3,RAB33B,GOLGA5,HSP90B1,UBE2M,GIT2,UBA52,FUT8 |
| 1.262e-06 | -13.58 | localization within membrane | biological process | GO:0051668 | 549 | 213 | 18204 | 5365 |
VPS26A,TIMM10,CDH13,ZDHHC24,VPS39,ASB3,PEX26,TOMM22,LMNA,CMTM6,RAB29,SLC1A1,VPS26C,RALA,EMC2,EMC4,HYCC1,ROMO1,NSG1,ATP1B1,HYCC2,TM9SF1,DLG1,DLG3,LHFPL4,EMC1,RAB13,CPE,SNX12,TSPAN5,SEC61B,TIMM8A,ARL5B,HGS,TMEM88,RAMP3,RER1,STXBP1,PIP5K1A,HPS6,TTC8,TSPAN15,LRP6,SLMAP,LMNB1,HSP90AA1,SNAP25,C1QL2,MTCH2,EMC10,FLOT1,AKT2,ERRFI1,INPP5K,FRMD8,RTP4,BAX,FERMT2,ATP1B3,TOMM40,CAMLG,KCNB1,ZDHHC15,DPP10,PREPL,LRRC4,ZDHHC14,SEC61G,EHD4,VAMP5,AQP11,CD81,ARL6IP5,PTN,TNIK,CACNG3,HSPA5,CRB3,SMURF1,EMP2,KCNIP3,EXOC1,SNX3,TRAM2,PIGW,OPTN,CAV3,CAV1,TIMM29,FCHO2,LIN7B,TESC,S100A10,SSR3,CHRDL1,PLEKHF1,STX16,AGER,ZDHHC4,ABHD17A,CDK5,RAB14,GOLPH3L,RAB6A,UBL4A,EPHA2,EMC6,RAB11B,RAP1A,RILPL2,SRP14,RAB11A,TIMM13,RAB6B,SEC63,TNF,ADIPOQ,SPTBN1,CD2,ROCK2,SCN3B,CACNB3,TRMT10B,EXOC8,VAMP3,PICK1,ARF6,EXOC5,RAB35,NPTX1,STX6,WDR83OS,LAMTOR1,SEC61A1,GLRB,NLGN2,RAB31,SSNA1,TIMM8B,FGF13,LGI1,PEX3,ATAD1,NHERF1,TOMM20,VAMP2,PSMD10,TRAM1L1,ATG3,SRPRA,NETO2,ARL6,EHD3,SH3GLB1,EXOC2,TMEM147,TOMM70,NETO1,DLG4,THY1,TM9SF4,TRAM1,P2RY1,C1QL3,ADORA1,LARGE1,ROCK1,RAB8B,SSR1,EHD1,ZFAND2B,SSR2,SEC23A,RRAGA,TIAM1,CACNB2,SDCBP,SRPRB,MADCAM1,NLGN1,BCS1L,TOMM7,LIN7C,ANKRD50,SGTA,GORASP2,CCDC22,F11R,AGK,SRP72,ACAP2,MTX2,CCDC47,WDR19,RAP2A,GOLGA7B,STX12,JUP,TOMM6,SEC61A2,GPHN,SYS1,RAB32,SRP54,SNX17,SAMM50,TPBG,SEC62,MAIP1,EMC9,EMC8,IKBKB,GOLGA7 |
| 1.272e-06 | -13.57 | MCAM (melanoma cell adhesion molecule) | protein interactions | 4162 | 464 | 177 | 19454 | 5460 |
NECTIN2,RALA,ROCK1,SRC,SPRED1,RAB2A,VAMP5,SLC6A6,GORASP2,CNNM4,ATP1A1,LIN7C,PML,RAB9A,SPTBN1,CDC42,ARL15,CSNK1G3,LEMD3,RAP1B,SLC39A10,ADD1,FLRT2,RAC2,VTI1B,CAND1,PLSCR3,SVIP,SLC38A2,TMPO,DPP4,PALM2AKAP2,ATP2B4,RAB13,SLC16A1,AKAP12,SLC6A8,SNAP29,TFRC,BMPR2,NHERF1,UGCG,GNAI3,SPRY1,LAMTOR1,ICAM1,RAB5A,ADRB2,ITGAV,ABCC5,PACSIN3,USP6NL,CLDN4,IL6ST,KLC2,TNIK,RAB35,RHOH,LAMP2,RAB5C,WWP2,PPFIBP1,CTNNB1,ANKRD50,CDK5,EFNB1,KRAS,ROCK2,VDAC1,SLC20A2,SLC35A2,RAB4A,RND3,ADCY3,VAMP3,GAB1,CTNNA1,MSN,YES1,RHOJ,SNX3,FERMT2,SH3BP4,VIRMA,GNAI2,RALB,FLRT3,DEPDC1B,LGALS8,EPHA2,RHOU,YKT6,IL1RAP,NF2,MPZ,CDC42EP4,SLC5A6,PIP5K1A,CNP,EHD3,CTDSP1,SLC12A2,PICALM,STOM,AGAP1,HRAS,EHBP1,CDCA3,ALCAM,ARF6,CAV1,TMEM199,RELL1,LAMP3,DAG1,RAB23,TIAM1,ESYT1,EHD4,DLG1,SNAP23,CTNND1,ZDHHC8,CASK,SLC23A2,GNG12,LGALS3,CHCHD3,TNPO3,NIBAN2,RAB11A,PKP4,MYO6,WDR20,RHOB,SLC7A11,NPTN,CNTN1,CYFIP2,RP2,STX7,ARL6,GJC1,NOTCH2,EHD1,RND2,STXBP1,SLC25A3,SPRED2,ARL11,PLEKHO2,GJA1,AFAP1L2,MPP1,DIRAS3,TMEM237,WDR44,RHOG,C2CD2L,LRRC57,RPL23,SLC20A1,JAK1,PLCB1,S100A10,RPS27A,AHCYL1,FLOT1,MARCKSL1,E2F4,IFNGR1,DCUN1D3,TULP3,CTNNA2,VAMP2,ITGB5,CYB5B |
| 1.276e-06 | -13.57 | WIF1 (WNT inhibitory factor 1) | protein interactions | 11197 | 143 | 67 | 19454 | 5460 |
ZMPSTE24,ARMT1,ADK,STK24,PIP4K2C,TOMM40,RNF40,HMOX2,GALE,HSPA14,NAA50,GSTK1,UQCRQ,CSTF3,DYRK1A,MGST3,IP6K1,F11R,SNX3,GTF2F1,CYRIB,CYB5R3,OXSR1,GAMT,RPRD1B,VAPB,MAP2K1,IDH2,PICALM,EHD1,UBLCP1,SF3A1,TOMM22,PPP1R8,UFL1,CWF19L1,EMG1,RAB5A,SNCG,RB1CC1,SMCHD1,CRADD,NT5C2,ICOS,SYNJ2BP,MAP1S,NUP35,SNX1,CYB5A,PTPN1,MGME1,NDUFA12,SH3GLB1,PPME1,TFCP2,IK,PTRH2,NAA15,SUPT5H,MTCH2,RDH11,PRPS1,RAB13,PPP1R12A,EHD4,NAE1,SFXN1 |
| 1.281e-06 | -13.57 | negative regulation of vasculature development | biological process | GO:1901343 | 158 | 75 | 18204 | 5365 |
MIR30B,MIR21,MIR146A,MIR492,PGK1,MIR375,MIR221,NIBAN2,MIR503,PPARG,MIR212,CCR2,GADD45A,MIR222,SLC12A2,MIR30E,RGCC,MIR377,MIR20A,MIR193A,GHRL,MIR214,MIR17,MIR424,MIR29A,GTF2I,MIR16-1,HGS,MIR125A,STAT1,PML,MECP2,ATP2B4,CXCL10,MIR137,MIR29C,KRIT1,MIR361,MIR939,FASLG,KLF4,MIR10A,EMILIN1,KLK3,MIR34C,EPHA2,MIR885,MINAR1,MIR495,MIR205,PRL,VASH1,ADAMTS1,MIR34A,AGO1,MIR143,MIR15A,ROCK1,CTNNB1,SYNJ2BP,MIR145,MIR24-1,MIR101-1,MIR185,TGFB2,MIR1298,MIR640,ROCK2,EFNA3,MIR34B,MIR106B,TNF,IL17F,MIR505,SPRED1 |
| 1.288e-06 | -13.56 | MARCHF5 (membrane associated ring-CH-type finger 5) | protein interactions | 54708 | 204 | 89 | 19454 | 5460 |
PTPN1,UBE2N,TOMM70,SLC25A46,LAMP3,MFN1,MED27,DNAJC7,MAP1B,NSDHL,EMC2,YIF1A,RIGI,FKBP8,CCDC47,GNPDA2,NEFL,OPTN,UBE2I,C9orf72,CREB3,CCNB1,UBE2E3,ATP1A1,GRAMD2B,SOD1,SQSTM1,MAVS,MEA1,KDM1A,YKT6,TOMM20,TMEM209,TIMMDC1,CAPN1,UBE2W,RPA2,MANBAL,DDX4,PPP2CB,DNAJB9,HSP90AB1,PSMD3,SLC25A26,MARCHF5,PTPN5,FATE1,DDRGK1,UBE2D1,TRAF6,PEX3,FBXO11,USP30,HS2ST1,FLOT1,STBD1,MIEF1,CYB5R1,FAF2,STIM1,NME1,MTA2,TMEM14B,CYB5B,VDAC2,RMDN3,MYC,RAB11A,PSMD1,TOMM40,ELMOD2,MBLAC2,BLVRA,CGRRF1,LMNB1,FIS1,HSP90AA1,RIT1,EXD2,HSPA8,AKAP1,TRA2B,UBE2D3,PSMC1,PXMP2,SKP1,TANK,FUNDC1,VAPB |
| 1.319e-06 | -13.54 | TUBA1C (tubulin alpha 1c) | protein interactions | 84790 | 449 | 172 | 19454 | 5460 |
MAP2K3,MGARP,EEF1A1,CCT5,INSIG2,TP53,TRIM6,FBP1,UBL4A,COMTD1,PHC1,TFCP2,PPP1R12A,FAF1,LTA,MEPCE,FBXO25,SRPRB,VRK1,HUWE1,TCP11L2,NEDD8,GAPDH,CD81,COPS5,HDAC6,PPM1D,ATP5MG,SNRNP70,H2AC4,SHC1,FAM187B,TUBG1,EPOP,TES,DSTN,AIFM1,SSBP1,CDC5L,TMPO,MDM2,DCUN1D1,CAND1,CDK7,CFTR,CDC42,HCST,GABRA1,WDR5B,WTAP,ARL15,E2F6,HEXIM1,DYRK2,METTL14,SSR1,CTDSP1,RPA2,GALNT1,SQSTM1,RNF113A,CST11,TMEM263,PML,SIRT7,BAP1,RPA3,HSPA5,TMEM209,PIK3R2,RPL4,FBXW7,NF2,IRF7,ATP5F1A,SMARCA5,TRIM32,UBE2H,ATP1A1,TRIM23,TXNIP,RC3H2,SPOP,PTEN,PSMC5,TUBA1B,UQCRQ,SH3BGRL,CDC20,PRKCE,KCTD9,MSX2,TUBA1A,FAF2,TXNRD1,B3GNT2,ERRFI1,STK16,OTULIN,AQP3,TUBB4B,RPN1,EZH2,BAG2,CCT8,SLC25A5,NEK9,OSTM1,HSPD1,COPS4,FLOT1,CDK20,CBX7,KRAS,G3BP1,RBBP7,PCGF3,DDRGK1,P2RY10,FAM174A,UBXN6,HSPB1,POU5F1,CBL,MGMT,HAX1,AGR2,EED,MAGED2,FBXO32,PHB1,RPL8,SSR2,CCT7,OPRL1,HSP90AB1,RAMP3,EGLN3,ELK1,DYNC1I2,ATXN10,SUMO2,TCP1,INSYN2A,YIPF5,PIH1D1,SLC25A3,PSMA3,PCGF2,SF3B1,ATP5MK,STAU1,RNF5,NPTN,UFL1,BRINP3,NXPH3,CUL2,CUL3,MYC,THTPA,FIS1,KLK5,PSMD14,BRCA1,CCT2,SEC61B,AP2M1,CD79B,TUBB,RBBP4,ATP5F1B |
| 1.319e-06 | -13.54 | POLR2K (RNA polymerase II, I and III subunit K) | protein interactions | 5440 | 154 | 71 | 19454 | 5460 |
MED31,PIH1D1,RPRD1B,POLR1D,SMYD3,SUPT4H1,INTS6L,TPT1,POLR1H,FBXW7,SNRPA,PFDN2,POLR1B,PFDN6,MAF1,MED10,BRCA1,FBXO7,SNRPB,MYC,POLR2B,ESR2,SRC,MED17,GPN2,INTS10,POLR3B,INTS12,GTF2F1,POLR2F,GTF2F2,ZNF655,POLR3H,POLR2G,POLR2C,POLR2D,RPAP2,PSMB9,PPP2R1A,GTF2E2,TRMT1L,RAF1,MED9,SUPT5H,PDRG1,SSRP1,MNAT1,SEM1,KRAS,KPNA2,KGD4,DNAAF10,RUVBL1,RUVBL2,RPAP3,MED4,MED27,MED21,MED29,GTF2E1,CSNK2A1,XPO1,POLR3GL,MOV10,ASNSD1,POLR3F,TOP1,POLR2I,RPRD1A,GTF2B,POLR2L |
| 1.324e-06 | -13.54 | CRNKL1 (crooked neck pre-mRNA splicing factor 1) | protein interactions | 51340 | 165 | 75 | 19454 | 5460 |
FBXO22,SNRNP40,VIRMA,SNRPB2,CCNF,PSPC1,DLST,EIF4A3,SF3B4,SNRPD2,LMNB1,PSMD14,HSP90AA1,ELAVL2,RIT1,MYC,HNRNPC,FBXO7,AR,SNRPB,TRA2B,STAU1,COIL,RPA3,DDX39B,SMARCD3,SNRPA,SIRT7,NKAPD1,SF3B1,CLK1,LMNA,RPA2,LSM2,TFIP11,WDR83,SF3A1,SNRPN,RALYL,RPS16,FZR1,TOP1,SNRPA1,CWC15,CDC5L,PRCC,FBXO32,EED,KIAA1143,SNRNP70,HSPB1,MAGOH,IFI16,PRPF19,ZCCHC10,HNRNPA1,TSSC4,CTNNBL1,CDC40,KRAS,NUP42,SSRP1,SNRPG,SNIP1,HNRNPA2B1,ZC3H11A,SRSF7,EZH2,TUBB4B,ILF2,RHOBTB1,SNRPE,RAF1,SUPT5H,NCSTN |
| 1.335e-06 | -13.53 | SLC4A1AP (solute carrier family 4 member 1 adaptor protein) | protein interactions | 22950 | 127 | 61 | 19454 | 5460 |
SNRPA1,THOC1,PRNP,PPP2CB,KRR1,MAP4,CSNK2A1,INSYN1,TCEANC2,IFI16,ZNF24,SOCS2,VTA1,SNRPG,MDC1,KPNA2,HAPSTR1,EWSR1,SF3B5,SNRPE,PSMC3,CDK8,CBX3,MINDY3,PPP2R1A,SNRPB2,ESR2,SSH3,SNRNP40,FBXO22,PSMC5,SF3B4,SNRPD2,PRMT5,FAM177A1,SF3B6,CCNF,ZNF330,RBM7,UBE2H,PSMD1,TTC33,SNRPB,MCM4,DNAJC8,MYC,PSMC1,HSPA5,ASB3,KDM1A,SMC4,HSPA8,SF3B1,STK26,NUP50,RPA3,PML,EIF4B,ACACA,RPA2,SNRPN |
| 1.345e-06 | -13.52 | SNX6 (sorting nexin 6) | protein interactions | 58533 | 207 | 90 | 19454 | 5460 |
HSD17B11,HCLS1,HRAS,STX6,ARF6,LAMP3,DNAJB2,BMPR1B,HENMT1,TSNAX,CHCHD1,IGF1R,HAPSTR1,ATG4A,TGFBR2,TOLLIP,APEH,FURIN,DISC1,TFRC,GTF2A1,OPTN,INPP5K,RHOJ,SNX3,DNAJC5,ZNF687,CABCOCO1,SNX5,NRP1,RAB9A,RPA3,BAP1,DVL2,GTF2I,SNRNP27,TPT1,LEPR,FGFR1,USP46,GJA1,TNIK,RAB35,WIF1,DIRAS3,NTMT1,LRRC61,SNX1,SNX2,TBC1D5,SPATA2,ATG7,RAB5C,NDC80,VPS26A,ATG9A,LAMP2,IFI16,PEX3,FLOT1,PAEP,G3BP1,KRAS,RAB4A,VPS33A,FAM43A,TSN,MTM1,STAT1,BAG3,BRMS1,CUL3,RAB11A,NIBAN2,DNAJB6,FAM221A,KLHL1,NTRK3,BRCA1,RHOB,LAMTOR1,RAB5A,HSPA8,COIL,STX7,PHB2,BET1,SHMT1,ATP6V1C1,VAPB |
| 1.351e-06 | -13.51 | positive regulation of MAPK cascade | biological process | GO:0043410 | 473 | 187 | 18204 | 5365 |
OSM,TNFAIP8L3,GPNMB,RELL2,NTRK2,OPRK1,NTRK3,C1QTNF1,EPO,TPBG,FGF23,IL34,VEGFA,SEMA7A,EZH2,CHRNA7,LAMTOR2,RB1CC1,PRDX2,LAMTOR3,FGFR1,P2RY1,ACKR3,ANGPT1,GHR,SRC,ADORA1,ADRA1A,FGF22,PTPN1,PTPN11,PHB2,LEP,TLR4,PIK3CG,GPR37,LPAR1,SDCBP,DOK5,ICAM1,AVPI1,MAP3K3,ROCK1,DDR1,MIR181D,LAMTOR1,PRKCA,GADD45A,TRAF6,DIRAS1,CCL19,CHI3L1,NPSR1,RELL1,MAP2K6,ZNF622,DRD1,NPY5R,FGF7,HMGB1,SYK,FGF16,CD40,FCGR2B,FBXW7,TRIM5,MIR23A,HRAS,PYCARD,AGER,FGF17,TNF,MAP3K11,ALKAL1,FGF3,DUSP22,ROCK2,RAF1,CX3CL1,MIR24-1,RAP1A,TRAF2,AVPR1B,EDA2R,RPS3,PHB1,PLCB1,TLR9,GADD45B,GLIPR2,MYD88,IGFBP3,SEMA4C,CD81,MIR519D,ARL6IP5,TNIK,CD4,MIR21,DOK4,DSTYK,TAB1,GPBAR1,CD36,LPAR2,MEF2C,CCL3,MIF,TPD52L1,DDT,HTR2A,ADRB1,MAP3K12,GRM1,GPR37L1,OR2AT4,TRAF7,STK3,OPRM1,DNAJC27,DOK6,AKAP12,TLR3,NDST1,MIR126,IGF1R,IL6,FERMT2,ERP29,GADD45G,DUSP19,CDC42,PPIA,PROK1,GHRL,CCL21,ADRB3,GNAI2,ANKRD6,KIT,EIF2AK2,MIRLET7B,LTBR,CRKL,AR,CARTPT,SOD1,DIRAS2,JAK2,PLA2G5,TIRAP,CAV2,RIT2,NRP1,FGF1,SHC1,CCR1,PRKCE,MAP2K1,RAMP3,DVL2,RAP1B,IGFBP4,WNT7A,PDE8A,SOX2,PTPN22,TGFB3,IL1B,DKK1,CCR7,TLR6,ADRB2,DRD3,HAND2,PDCD10,ACTA2,IGF1,NOTCH2,MAP2K3,IL1A,TGFB2,CTNNB1,FGF10,GH1,TMEM106A,MT3 |
| 1.353e-06 | -13.51 | Assembly of the pre-replicative complex | REACTOME pathways | R-HSA-68867 | 69 | 41 | 10285 | 3229 |
PSMA1,GMNN,PSMC3,PSMD14,PSMD4,MCM3,UBB,RPS27A,UBA52,PSME1,PSMB4,PSMD6,PSME2,PSMD10,ORC6,PSMD7,SEM1,PSMB9,PSMB10,PSMA5,PSMB11,PSMC5,PSMA4,MCM4,PSMA6,PSMB3,PSMB2,PSMD1,PSMA2,MCM6,PSMB6,PSMB1,PSMB7,MCM8,PSMD3,PSMC4,ORC5,PSMC1,PSMD12,PSMB5,PSMA3 |
| 1.365e-06 | -13.50 | NCOR1 (nuclear receptor corepressor 1) | protein interactions | 9611 | 329 | 132 | 19454 | 5460 |
EZH2,RBPJ,SMARCB1,SUPT5H,E2F4,TOP3B,VDR,SAP30,TULP3,H1-3,JUN,SOX2,GABARAPL1,ASF1A,TRIM37,ZBTB16,SSRP1,PAX6,BAG2,EWSR1,SLC39A3,LHX2,CBL,HNRNPD,CNOT2,INSYN1,SUMO2,RAB1B,PGR,NUP35,EGLN3,PHB1,CBFB,SIN3A,COPS2,EED,MAP1LC3A,CTBP1,PPARG,KLF3,CDKN1A,PPP1CB,PHB2,ZBTB5,TRIM52,ITGAV,C1D,NUP50,RAB5A,EP300,HDAC5,YWHAZ,SP1,TXNRD2,CREBBP,HNF1B,MYC,THAP7,SMARCE1,SNRNP40,B4GALT3,FBXO22,RBBP4,MATR3,ESR2,CBX5,ATXN1L,NFKBIA,ARF1,CPSF1,NFE2L2,CBX3,TRAPPC13,TAB2,TP53,EGR2,PPARA,MAP1LC3B,BACH1,KDM4B,H3C1,ZSCAN5A,RAB1A,TRAPPC2L,SMAD4,TAF9,KPNA1,NFKB1,ZMYND11,CSNK2A1,MIF,PRNP,ETV6,GTF2B,MYBL2,OLFM2,RPA2,PAX9,FUT8,CCND1,SF3A1,CCL3,GABARAPL2,FBXW7,KDM1A,HDAC3,GABARAP,BCL6,PIAS1,PML,SLC39A9,RPA3,SQSTM1,CLK1,MECP2,POU1F1,EXOSC1,IGF2BP1,RAB2A,CDC16,AR,PPP1CC,RUNX1,NR1H2,VIRMA,NR1I2,ENO1,ZBTB33,CREB1,CCNF,UBE2I,HEY2 |
| 1.367e-06 | -13.50 | PUM1 (pumilio RNA binding family member 1) | protein interactions | 9698 | 279 | 115 | 19454 | 5460 |
PABPC1,LSM14A,TRIM11,BAG2,ZC3H7A,MIR206,NUP42,G3BP1,E2F4,B3GNT2,TOP3B,GLE1,NUDT19,GTPBP1,CYB5B,OTULIN,FUBP3,MIR214,KRT8,FAM98A,NUP35,EGLN3,MIR143,VPS26A,SAV1,CNOT2,XPO1,CNOT8,YWHAG,CPEB1,YWHAH,MIR29C,YWHAB,MIR140,HSPB1,MIR1-1,DDX1,MCRIP2,EP300,AKAP1,HSPA8,YTHDF1,STAU1,FXR2,UFL1,G3BP2,MIR106A,PABPC5,CDKN1A,LARP4B,NUFIP2,LMBR1L,SIAH1,FBXO22,MATR3,PRRC2A,MIRLET7D,HNRNPC,SFN,MYC,MIR98,YWHAZ,FBXW11,GARRE1,MIR200A,MIR9-3,CNOT7,SEPHS1,YTHDF2,TNRC6C,SMAD1,APOBEC3D,MIR20A,MIR17,ILF2,SYNCRIP,MIR106B,MIR25,PRR3,DSTN,MIRLET7G,CAND1,GRSF1,MOV10,SNRNP70,MIR34A,SIRT7,SMG5,RNF113A,MIRLET7I,LSM12,FBXW7,LITAF,MIR107,MIR29A,AATF,RBFOX2,RBMS2,CFTR,AGO1,MIR1-2,MIR7-1,MIR21,SMAP2,CCNF,TRIM24,RPS20,VIRMA,CEP85,RC3H2,MIR145,UBE2H,ELAVL2,PAIP2,IGF2BP1 |
| 1.374e-06 | -13.50 | POU5F1 (POU class 5 homeobox 1) | protein interactions | 5460 | 332 | 133 | 19454 | 5460 |
PSMD3,HMGA1,MRPS35,DPY30,WWP2,PPIB,MRPL9,EIF3D,CTNNB1,AGR2,PSMD10,POU5F1,PDAP1,RPRD1A,FABP5,SIN3A,HDHD5,NOP58,SNRPA1,CCAR2,TCP1,PEG10,PPIA,CETN2,MAX,RPL29,TUBA1A,H1-3,SOX2,RPS7,EEF2,TUBB4B,EZH2,RPS23,RPL31,ABCF1,NDUFA4,EWSR1,BAG2,RTCB,H1-6,GTF3C3,PDE6A,ATG101,MLF2,RBM27,SERPINH1,LSM14B,TRMT6,TUBB,NDUFAF4,SNRPB2,H1-5,PRDX3,SOX21,RPE,CTBP1,NDUFA5,FOXD3,HSPA8,HADHA,EMG1,TRA2B,PPP2R3A,NDUFS2,PRCP,STAU1,POLA2,USP3,RBM17,GAPDH,ELOC,API5,TUBG1,CRBN,RPL24,USP15,SRP14,TOP1,ZBTB2,CDC5L,TOR3A,MRPL47,IPO8,EEF1A1,NDUFS3,PCMTD2,ILF2,RAD23B,OTX2,RAB13,HUWE1,HNRNPK,BACH1,KPNA2,FASTKD5,MSH6,MNAT1,SUGP1,PSMB2,NAA50,ATF4,TIA1,ATP5F1A,AR,NR0B1,POU1F1,ANAPC4,STUB1,DTYMK,TRAF7,GANAB,TXN,SCML2,RPL22,DEK,GTF3C4,KDELR2,ELP3,CFTR,XBP1,MRPS34,P3H1,CDAN1,LEMD3,ARMCX1,ITM2B,NBN,MRPL17,EIF5B,SMC4,HMGB1,MBD3 |
| 1.376e-06 | -13.50 | DDX10 (DEAD-box helicase 10) | protein interactions | 1662 | 179 | 80 | 19454 | 5460 |
NOL12,RPS2,RPL10A,DDX23,ATG7,NGDN,DDRGK1,IFI16,KLF9,ZBTB2,CAND1,RPS16,RPS10,LYAR,EED,RPL8,SRP14,KRR1,SRSF1,RPL18,CDK8,RBM34,AURKAIP1,RPL15,RAF1,SRFBP1,RPSA,TP53,E2F4,SRSF4,RPL17,PTGES3,H3C1,KRAS,H1-6,RPL3,RPL23A,RPS24,TRIM11,SNIP1,RPL31,DNAJB6,RIT1,H1-1,CKB,LMNB1,ATG3,ZNF668,FBXO7,DNAJC8,MYC,RPL7A,ESR2,VIRMA,RPL19,RPL10,APEX1,RPL13A,RPL35,CSNK2B,RPL37A,FGFBP1,PRKRA,RPS3,LMBR1L,ZNF330,RPLP0,RPA2,FGF13,CDK7,H1-5,G3BP2,DGCR8,NPM3,FBXW7,RPL4,STAU1,NOP53,RPA3,SIRT7 |
| 1.389e-06 | -13.49 | TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C) | protein interactions | 9013 | 106 | 53 | 19454 | 5460 |
RIT1,ATG3,CCT2,MECP2,UFD1,RPL7A,RRN3,MYC,SRPK2,ESR2,RPL13A,TRIM24,PRKRA,RPL37A,FGFBP1,TRIM44,RPLP0,APOBEC3C,FGF13,RPS14,STAU1,RPL4,TTR,NPM3,P4HA2,HSPA8,BRD3,RPL10A,CSNK2A1,ZCCHC10,SAV1,CCT7,SURF6,STK3,VPS26C,TCP1,PRNP,RPL8,RBM34,RPL15,H2AX,TAF1D,CCT5,TP53,RAF1,RIGI,RPL17,SMN1,RPL28,FGF12,KRAS,RPL3,HSPD1 |
| 1.390e-06 | -13.49 | mRNA processing | biological process | GO:0006397 | 444 | 177 | 18204 | 5365 |
CLP1,DBR1,ELAVL4,DHX9,AKAP17A,SF3A1,THOC3,PRMT5,LSM4,SRSF7,MAGOH,SNRPD3,WTAP,GEMIN8,SRPK2,WDR77,CSTF3,SUGP1,ZMAT2,LSM2,RPRD1B,SMNDC1,CPEB1,HNRNPA0,CPSF4,CWF19L1,SART3,CDK12,CWC15,RBM23,SF3B5,LSM8,DDX39A,PRPF19,DHX15,CDC5L,COIL,RPRD1A,SNRPE,SMU1,HNRNPC,SNRPA1,SNIP1,TSSC4,LUC7L3,SF3B4,SMN1,TENT4A,SRSF12,SREK1IP1,THOC6,THRAP3,DDX1,HNRNPA1,SNRPB2,RNASEL,DDX42,THOC2,ARMC7,DDX39B,SCNM1,LSM5,VIRMA,SLU7,ZCRB1,ESS2,RBM22,TIA1,BUD31,ALKBH5,SYNCRIP,WBP11,SNRNP70,DHX16,SNRPG,LSM10,SNRPA,RAMAC,ARB2A,ECD,RBFOX3,CDC73,RNF113A,KHDC4,PAPOLA,FASTKD5,SNRNP48,RBFOX2,SRSF10,SSU72,WDR83,HNRNPL,HNRNPH3,SNRNP27,PRPF4,CCAR2,CMTR1,SF3B1,RBM17,SRSF8,SRSF2,EIF4A3,SNRPN,CNOT6L,PDE12,H2AB1,PRPF31,SNRPD1,RBM38,MFAP1,AKAP8L,PPIH,TXNL4A,CASC3,GCFC2,LSM3,TSEN34,FRA10AC1,SNRPD2,RBM5,HNRNPF,RBM42,KIN,PRPF18,TRA2B,IK,RSRC1,PABPC1,CD2BP2,NRDE2,SAP18,ZNF473,CMTR2,SRSF1,CSTF2T,GEMIN7,HSPA8,PPIL3,RBMX2,USP39,HNRNPK,TSEN54,SF3B6,SNRPB,NONO,RBM41,HNRNPA2B1,NOVA1,DDX23,ZRANB2,TENT2,RBM27,ZMAT5,THOC1,DHX38,MAGOHB,NCBP2,DDX5,PPWD1,TRA2A,ALYREF,SNRNP40,CPSF2,CTNNBL1,DDX46,PQBP1,TFIP11,RBM15B,METTL14,TRUB1,CDC40,LSM6,LGALS3,UBL5,ZNF326,SRSF4,CELF6 |
| 1.395e-06 | -13.48 | defense response to other organism | biological process | GO:0098542 | 1006 | 364 | 18204 | 5365 |
TMED1,MATR3,MX1,VPS26B,TRIM34,CXCL14,DAPK3,RPL39,IFNGR1,MX2,FCER1G,DDX1,TREML1,IL12B,POLR3B,RNASEL,FGR,RNASE6,MIR223,G3BP2,CXCL9,IFNA10,PYDC2,RSAD2,IL6,RTP4,PI3,SH2D1A,JAK1,WFDC5,LEAP2,EXOC1,SYNCRIP,ATG7,TLR9,IFNK,DNAJC3,CXCL3,IFNA2,DHX16,LILRA2,AQP4,NMI,CLEC6A,IFI27,SIN3A,RIGI,LYAR,HP,CD36,CDC42EP4,POLR3F,PMAIP1,OPTN,IL1B,DEFB129,ZMYND11,TANK,ISG20,TLR6,IFNA13,FBXO9,PPP1R11,UBE2W,ROMO1,TMEM106A,CXCL11,CCL24,HYAL2,TUBB4B,CD14,EIF2AK2,TOLLIP,CDC42EP2,RPL13A,UBE2N,KLRD1,MIRLET7B,TIRAP,STAT1,ACP5,BST2,LYZL6,STXBP1,JAK2,BCL2L1,RAB27A,DEFB114,LACC1,TRIM35,SRC,NT5C3A,IL18,PRDX1,FASLG,RNASE4,PIK3CG,REG1B,TFEB,MIR140,TRIM21,CD58,PHB2,COTL1,ZNF175,HEXIM1,IFNG,TAB2,FAU,SERINC3,IL17F,CD47,LGR4,CAMP,TMEM45B,PRKRA,CCL1,IRF1,PQBP1,TRIM10,ACTR2,BPIFB1,IFI16,OPRK1,NDUFAF4,TLR8,MIRLET7I,TICAM1,TLR1,LYZ,BNIP3L,SAMHD1,IL23A,CD40,RAB14,OTULIN,CCL23,NLRP1,CH25H,CLU,SYK,TRIM5,APOBEC3C,S100A8,RNASE9,SARM1,ATG16L1,LGALS8,CD2,IFIT2,LACRT,YES1,TRIM62,KLRC2,DEFB115,GPAM,TUSC2,TRIM32,TICAM2,TLR10,TRAF6,TLR2,RARRES2,APOBEC3A,XRCC5,TBK1,BPGM,SFTPD,CCL19,TLR5,VAMP3,TUBB,PML,SEMG2,PSPC1,CCL2,TASL,CCL4L1,KCNJ8,NFKB1,ARG2,RNASET2,LILRB1,ELMOD2,PELI3,MOV10,IL12A,BCL10,CCL3,BPIFB3,MIF,APOBEC3D,AKAP1,TNFSF8,STX8,IRF3,DEFB124,TRIM68,TLR3,CCL5,CNPY3,G3BP1,APOBEC3G,IFNAR1,DAPK1,CDC42,CCL17,MYD88,IRF9,SLPI,IFIH1,MIR146A,PLPP6,TRIM26,NLRP9,CD4,CLDN1,APOBEC3F,RNASE1,CD46,MAVS,TRIM11,IFNB1,NCR3LG1,CHID1,POLR3H,MSRB1,TAX1BP1,RAB1A,ZYX,C1QC,TTC4,DHX9,VAMP8,IRF2,HCFC2,WFDC13,CST11,CCL20,JCHAIN,CXCL1,ISG15,DDIT4,UAP1,CLPB,FCN2,CD209,NOTCH2,SRPK2,TRIM8,NCK1,JAGN1,TF,DEFB116,DEFB1,STAT2,FAM3A,EXOSC4,CCL21,CYBC1,TRIM22,ATP1B1,IFI35,BECN1,TRIM29,DHX15,USP14,TLR7,IRF7,NLRP6,H2BC11,OAS1,CCDC92,REG1A,FCGR1A,IRF8,SHC1,CHGA,MRC1,MAP3K14,FOSL2,LTA,BPIFA2,MIR26B,TMEM33,TRIM27,TLR4,IFI6,NONO,SEC14L1,CCL8,CCL11,SPAG11B,TP53,LYZL4,CXCL8,H2BC12,ENDOD1,CLEC7A,IL21,AZI2,IRAK4,TNFAIP8L2,TRIM52,NQO1,APOBEC3H,LYG2,SLC15A2,PPARG,CXCL13,CNOT7,TRIM15,SDHAF4,RBCK1,IL34,IKBKB,GAPDH,CYP27B1,LGALS3,DROSHA,YTHDF2,EPHA2,PLAC8,MBL2,HMGB1,CD1D,IL1RAP,BATF,PYCARD,HRAS,RBPJ,XCL1,IL10,RAF1,CX3CL1,TNF,DEFB121,TRIM6,LY96,PHB1,VAMP7,PDE12,TRAF2,CX3CR1,NMBR,CEBPG,CCL25,NLRP3,PLSCR1,F2,TIFA,IRF4,AIF1,APOBEC3B,LSM14A,TNFRSF14,VAMP2,CXCL10,NLRP2,TRIM23,CITED1,CGAS,CCL18,CASP4 |
| 1.411e-06 | -13.47 | PTPN11 (protein tyrosine phosphatase non-receptor type 11) | protein interactions | 5781 | 347 | 138 | 19454 | 5460 |
PSMC3,CTLA4,PIK3CA,GPX7,GGCT,PPIF,SOCS3,CCT5,KBTBD4,RIGI,RNF20,RPIA,IGF1R,NTRK2,PSME1,NOSIP,RAB1A,DDR1,STYK1,NXT2,SHC1,MED21,GTF2A2,ORMDL3,FCGR2A,FCGR2B,HDAC6,CALR,CAV1,PRNP,PSMB1,LDLR,SYNCRIP,TREML1,SSBP1,CD274,PRKCA,STAMBP,LEPR,MET,FGFR1,METTL14,HSP90B1,RPA2,CTDSP1,SNRNP27,ARHGAP1,HSPA5,PIK3R2,FBXW7,SIT1,CERS2,GPX4,PRKCB,CSTB,PML,RPA3,UBE2H,CDC73,EPHA2,TXNIP,CHRAC1,IFNAR1,AR,GMNN,MTPN,ATP5F1A,PTPN11,MPIG6B,AKT1,TRIM32,SRC,VIRMA,TECR,STAT5A,PSMA6,GAB1,CRKL,GHR,IFNGR1,GTF2E2,ACTN4,AHCYL1,HNRNPDL,PSMD12,EPHA4,KIT,PIK3CG,JAK1,CCT8,HSPD1,CBL,PDCD1,TRAF6,SKIC8,CTNNB1,SIGLEC5,PIK3R1,GSTM3,PRPF19,PDIA3,CCT7,HSP90AB1,CACYBP,SRSF10,KCTD10,RANGRF,PSMB4,PTK7,DNM2,LILRB4,PIH1D1,MAP2K1,FRS3,IL6ST,OXCT1,STAU1,HSPA8,TMEM220,RPS28,CXCR4,LUM,ILK,DNAJB6,RIT1,COP1,SLC38A1,NTRK3,CYP1A1,RAB11A,PSMA4,HNRNPC,JAK2,LGALS3,STAT1,TCEAL1,EFHD2,PAPSS2 |
| 1.427e-06 | -13.46 | NOP2 (NOP2 nucleolar protein) | protein interactions | 4839 | 398 | 155 | 19454 | 5460 |
NDN,SRPK2,CCNF,ZNF330,EIF2AK2,PRKRA,UBE2I,MECP2,RC3H2,ATP1A1,UBE2H,RPF2,RPL7A,RPL26,H2BC9,CEP70,KPNA6,PPP1CC,DGCR8,NPM3,RPL4,HMGB1,BRIX1,UTP23,AATF,RPA3,SIRT7,PML,RNF113A,MTDH,LMNA,RPA2,METTL14,UTP15,RPLP0,RPL26L1,KLF4,MACROH2A2,ZNF770,ATG16L1,CDC42,FZR1,RPS16,CAND1,DNAJC1,TOP1,CDK9,DKC1,ZBTB2,SURF6,ZNF7,CDC5L,SYNCRIP,KRR1,ALYREF,RPL32,RCHY1,LDLR,ARL4D,CHCHD1,MPHOSPH10,SNRNP70,RPS2,CDK12,NOL12,RPL10A,GRSF1,MOV10,COPS5,HDAC6,H3C1,IMP4,RIGI,RPL17,SNIP1,RPL23A,RPL3,RBM34,DNAJC2,ILF2,NUPR1,TP53,TAF1D,RPL15,MATR3,RPF1,APEX1,RPL19,RPL10,ZNF22,ZNF189,RPL37A,LMNB1,FTSJ3,BRCA1,RPS5,NSA2,H1-1,DNAJB6,MYC,GRB10,CUL3,THAP7,ZNF668,UFL1,STAU1,NOP53,G3BP2,HDAC5,HSPA8,EP300,PPARG,MAP2K1,PIH1D1,MTF1,H1-5,NOP58,RPL7,SUMO2,RPL8,PHB1,MRTO4,EED,RPLP2,HP1BP3,DDX23,MED4,RPL23,LHX2,IFI16,PCNX1,RPL6,WWP2,DDRGK1,KRAS,G3BP1,RPL28,CDCA7L,RPS4X,SSRP1,RPL31,RPS24,EZH2,CHMP4C,HDAC11,RPL18,SART3,RAF1,TOP3B,MAGEB10,NCSTN,SOX2,MAK16,RPS7,LGR4 |
| 1.434e-06 | -13.45 | FASTKD5 (FAST kinase domains 5) | protein interactions | 60493 | 288 | 118 | 19454 | 5460 |
GRSF1,TUBG1,MRPS9,SSBP1,COX4I1,DBT,ATP5PD,MRPS23,MRPL24,MRPL50,HADH,PPIF,MGARP,BCS1L,ATP5PB,MRPL47,NDUFA2,MRPL49,NDUFS3,MRPS18B,CLPB,ATP5PF,MRPS18C,MRPS33,HSPE1,TUFM,NDUFAF2,PYCR2,MRPS16,MRPS28,TRIM27,ACAT1,CCNF,MRPL53,ZNF330,IDE,MRPS21,KLRD1,KCNH1,TIMMDC1,MTRES1,MRPS34,RPA2,QRSL1,DLAT,GFM1,MRPL20,POLDIP2,PDHB,NME4,MRPL41,MRPL40,NDUFV2,MRPL9,CLPX,MTRF1,MAPK4,STOML2,MRPS35,POU5F1,PEX3,MRPS26,RHOG,GATD3,FAHD1,PHB1,NDUFS8,EGLN3,TMEM59,NCSTN,ERLIN2,HSDL2,ETFB,NDUFA12,STK16,NUDT19,AQP3,NDUFS6,PDHA1,HINT2,MRPS11,COX8A,HSPD1,MRPS17,IMMP2L,ETFA,ATP5F1D,KGD4,CCDC85B,MYC,AUH,PMPCA,PYCR1,CUL3,MRPS25,RHOB,MRPL13,TACO1,LMBR1L,DLST,APLNR,NDUFAF4,ATP5F1B,NPY2R,NDUFAF3,MRPL12,NDUFA5,ATP5PO,MRPS18A,UBAC2,AKAP1,EXD2,COIL,MRPS7,HSCB,NDUFS2,NPTN,STAU1 |
| 1.445e-06 | -13.45 | establishment of protein localization to mitochondrion | biological process | GO:0072655 | 75 | 42 | 18204 | 5365 |
TIMM21,TOMM70,FIS1,TOMM7,HSP90AA1,TRMT10B,TIMM10,TIMM17A,GRPEL1,MTCH2,DDIT3,MTX2,TSPO,MGARP,TOMM22,AGK,HSPD1,AIFM1,AKT1,DNLZ,TIMM8A,AIP,TOMM40L,TOMM40,BAX,TOMM6,RALA,TIMM13,TIMM8B,DNAJC19,ROMO1,TOMM20,IMMP2L,TIMM23,SAMM50,FBXO7,GRPEL2,CHCHD4,BCS1L,PMPCA,TIMM29,MAIP1 |
| 1.448e-06 | -13.45 | ACBD5 (acyl-CoA binding domain containing 5) | protein interactions | 91452 | 196 | 86 | 19454 | 5460 |
DNAJC1,PEX13,ARF6,EGLN3,PEG10,TMPO,CNTROB,COX14,PTPN1,ARL10,HSD17B11,RAC2,RHOG,HAX1,PEX3,NFKB1,MOV10,NDC80,MARCHF5,SLC38A7,RAB5C,SLC25A46,EDEM1,GPRASP2,DDRGK1,USP30,RAB3B,FKBP8,RAB1A,PIK3AP1,TMT1A,GARRE1,STIM1,RPN1,CFAP36,CYB5B,PSMC3,UBL4A,TBK1,SNAP29,YTHDF2,DNAJC25,MTARC2,FAF2,IP6K1,PSMD4,SEC63,STUB1,RMDN3,SGTA,SEC61B,TMEM229B,FBXW11,FIS1,ANAPC4,LDHB,PSMD1,ST13,PPP2R3A,YKT6,TOMM20,PXMP2,RPA3,PRPF4,EXD2,HSPA8,RAB5A,AKAP1,DERL1,MAVS,TTC1,RPA2,VAPB,GRM2,SSR1,MYL6,TOMM22,PSMC4,NUP62,UBA52,ARHGAP1,OTULINL,RND2,SEC62,CDC42,ST7 |
| 1.451e-06 | -13.44 | ZW10 (zw10 kinetochore protein) | protein interactions | 9183 | 138 | 65 | 19454 | 5460 |
SCFD1,NAPA,VAMP5,OPRM1,GSTK1,GPR17,STX16,COPE,ACTB,MAD2L1,APLNR,VIRMA,EFNA5,CCNF,LMBR1L,S1PR4,SCN2B,CHRM4,SEC61B,RPA2,LMNA,USE1,STOM,SSR1,FAM234A,PGRMC1,BET1,SEC22B,OTULINL,HCST,CDC42,SEC62,CFTR,GOSR1,NPTN,RPA3,BAP1,EP300,DERL1,RAB9A,TRAF6,PSMD10,P2RY10,DDRGK1,LMAN1,ILVBL,TMPO,PTPN1,EEF1AKMT3,HSD17B11,RAC2,STIM1,SIGLECL1,RPN1,CYB5B,COMTD1,ACTR1A,MAPK10,CD80,ROCK2,PSEN1,TMT1A,RINT1,STX18,ACTR1B |
| 1.458e-06 | -13.44 | DNAJC30 (DnaJ heat shock protein family (Hsp40) member C30) | protein interactions | 84277 | 213 | 92 | 19454 | 5460 |
TMEM31,NDUFS3,BCS1L,SLC51A,CCDC47,TMEM126A,NDUFA2,FKBP8,LRP3,BSCL2,CLPB,ERO1A,MRPS18B,SLC16A1,EMC2,PSMD7,ELOC,CALR,COX5A,LMAN1,MSMO1,NDUFA1,MRPS9,COX4I1,NDUFB4,COX6C,P3H1,LMNA,MRPS34,GHITM,HSP90B1,SAMM50,NDUFAB1,TMEM106A,PSMC4,TIMMDC1,GRPEL1,POLDIP2,NDUFC2,TMEM126B,NBN,MFSD14B,CALU,DNAJC10,FBXO7,CREB3,MGST2,NDUFB10,PYCR2,SEC63,VIRMA,COPE,PYGM,GANAB,CHCHD6,CCNF,NDUFA12,RPN1,PDHA1,NDUFS6,ERP29,PDIA6,S100B,NDUFB5,HAX1,NDUFB8,PPIB,NDUFV2,FATE1,PDIA3,STOML2,NDUFS8,OPRL1,KCNA2,OCIAD2,NDUFA5,NDUFAF3,MTX2,MRPS7,EMC1,NDUFS2,JAGN1,TOMM40,NDUFB7,NDUFB6,CUL2,CHCHD3,NDUFAF4,PARL,REEP4,DKK3,DLST |
| 1.458e-06 | -13.44 | GLS (glutaminase) | protein interactions | 2744 | 213 | 92 | 19454 | 5460 |
ACAA2,EXD2,NGRN,STAU1,HSCB,BAG3,PMPCA,MRM2,MTG2,MYC,AUH,HTRA2,RIT1,TAFAZZIN,MTG1,CCDC90B,TACO1,PARL,TRIM29,TUBA1A,PI15,RAF1,PDHA1,PLS3,EZH2,COX8A,TRIM21,HINT2,HSPD1,IMMP2L,ETFA,TNF,TSPAN10,TAX1BP3,MTRF1,MRPS26,NAB2,RHOG,GATD3,FAHD1,YBEY,COX7A1,SSR2,PSME2,COX14,RMND1,ATXN10,CDC42,UQCRC1,SNRNP27,CAPN1,MTRES1,PARD6A,QRSL1,RPA2,GFM1,AMACR,RHOU,RPA3,CRYZ,TMEM167B,TUFM,DNAJC5,ETFBKMT,RSPH1,SNTA1,PTPMT1,UQCRC2,RHOJ,METTL15,AURKAIP1,MRPL11,MVD,GFM2,LRRN4CL,ABCE1,HAPSTR1,SFXN1,FASTKD5,LAMP3,GRSF1,CHCHD1,TMEM70,CDR2L,COX4I1,SSBP1,AIFM1,MALSU1,MYL12A,PRNP,FZR1,RPL35A |
| 1.461e-06 | -13.44 | LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 27258 | 114 | 56 | 19454 | 5460 |
DDRGK1,USP15,HSPB1,MAP4,BECN1,GSTA1,ALDH1A3,LSM5,KCTD10,SNRPD3,ZNF511,FZR1,SOX2,DDX39A,EEF1A1,SART3,SNRPE,LSM10,LSM14A,SNRPG,MEPCE,RUVBL1,EIF4EBP2,LSM4,CNOT7,G3BP1,SNRPB,PRPF31,CDKN2D,RIT1,EXOSC1,ICAM1,RC3H2,LSM6,ZMAT2,SNRPD2,SNRPD1,CCNF,ESR2,CLIC4,WDR83,WDR77,DDIT4L,HAUS2,KLC2,SH3GLB2,TFIP11,LSM2,KLF3,TNFAIP1,LSM12,PRPF4,LSM8,CCND3,PIAS1,UFL1 |
| 1.461e-06 | -13.44 | ADSS2 (adenylosuccinate synthase 2) | protein interactions | 159 | 114 | 56 | 19454 | 5460 |
EEF2,GNPNAT1,EEF1A1,CBX3,RPS11,CCT8,HSPD1,RPL31,IDH1,HSD17B10,PCNA,HSPE1,THRAP3,H3C1,RBBP7,KRAS,RPL17,IMPA2,PDIA3,AGR2,NME2,HSPB1,DCK,DSTN,PRNP,AASDHPPT,RPS16,TANK,RPE,RPA2,CTBP1,UBE2M,RPS28,RPA3,ARFIP1,NPB,HSPA8,FBXW7,OXCT1,NT5C3A,CDSN,CUL3,RAB11A,MYC,GMPS,PCBD1,CHRAC1,UBE2H,ARMT1,ATP1A1,OAT,EIF4A3,CCNF,RPS3,SGTA,UMPS |
| 1.475e-06 | -13.43 | IGF2R (insulin like growth factor 2 receptor) | protein interactions | 3482 | 294 | 120 | 19454 | 5460 |
TMT1A,SCPEP1,SLC39A3,EWSR1,SLC39A7,COX8A,GALC,KRAS,TOP3B,HEXA,DNAJC25,RPN1,STIM1,EZH2,RAB4A,STX12,RND3,RAB35,FBXO32,EED,MAP1LC3A,GJA1,RHOH,EGLN3,DIRAS3,HSP90AB1,NPC2,LAMP2,ATG9A,RAB5C,RHOG,XRCC5,HSPA8,EP300,RAB5A,PMAIP1,HSCB,PRCP,STAU1,STX7,CLDN4,BET1,SEC62,OTULINL,RND2,CTBP1,HEXB,LMBR1L,ARF1,SERINC1,SEC61B,ESR2,MAD2L2,RPL19,MYC,RAB11A,TM9SF4,SLC30A5,LAMTOR1,PLA2G15,RHOB,LMNB1,NTRK3,RAB1A,B3GALT2,GARRE1,ABCE1,IGF1R,LIPA,AGA,RAB3B,ARF4,MEPCE,CTSC,RIGI,DISC1,TRAPPC13,HRAS,HSD17B11,DSTN,RAC2,ARF6,DNAJC1,STX6,LMAN1,CAV1,NOP9,CSNK2A1,LAMP3,NCDN,SLC39A9,RHOU,RPA3,SIRT7,MGAT4B,ACP5,DERL1,SQSTM1,RAB9A,ATG16L1,CDC42,EIF3J,ST7,SSR1,UBE2M,MET,STUB1,VAMP3,B4GALT1,PTEN,CTSB,RHOJ,VIRMA,RNASET2,RAB2A,CTSD,AKT1,DNAJC5,IGF2BP1,SNX5 |
| 1.486e-06 | -13.42 | ABCC1 (ATP binding cassette subfamily C member 1 (ABCC1 blood group)) | protein interactions | 4363 | 130 | 62 | 19454 | 5460 |
VIRMA,ESR2,APEX1,SEC63,RHOJ,LGALS3,PSMC5,SEC61B,VDAC2,LMBR1L,LAMTOR1,BRCA1,RHOB,LGALS8,ATP5F1A,RAB2A,RAB11A,STX7,AZGP1,MRPL17,TACR1,DERL1,RAB9A,TMX2,RHOU,IDH3A,RND2,OTULINL,CDC42,NDUFAF3,DBT,LMAN1,DIRAS3,CAV1,HNRNPL,ALCAM,ARF6,RHOH,GJA1,RAC2,HRAS,RAB35,TMOD2,SMAD4,RHOG,LAMP3,CSNK2A1,LAMP2,DPP4,RAB5C,PDE2A,FKBP8,FLOT1,PTGES3,KRAS,TMEM33,VDAC1,COX8A,RND3,RPN1,EEF1A1,RPS7 |
| 1.492e-06 | -13.42 | SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1) | protein interactions | 51100 | 122 | 59 | 19454 | 5460 |
ARPC2,C1D,RAB5A,RABAC1,BAP1,STK38,HSCB,ABHD5,FUNDC1,COMMD3,AGTRAP,LAP3,TFIP11,SH3GLB2,GSTP1,P3H1,RPA2,UBE2I,CCNF,GADD45G,TAX1BP1,GORASP2,USP14,SUB1,CUL2,CDKN2D,CALU,BAX,CCDC22,LAMTOR1,NIF3L1,SYP,CHORDC1,DESI2,THG1L,CDK5,SEPTIN7,RABGGTB,GADD45A,SCYL2,PSMA1,TPD52,SYNGR3,SH3GLB1,ACTR2,PRCC,RPRD1A,DNM2,ACSL4,SIN3A,COQ8A,WIF1,VPS26C,SNX1,ZNF576,EDEM1,NDC80,CALR,DRG1 |
| 1.492e-06 | -13.42 | RAB5B (RAB5B, member RAS oncogene family) | protein interactions | 5869 | 122 | 59 | 19454 | 5460 |
HSPA5,HADHA,RAB5A,HSPA8,RABAC1,DUSP9,RPA3,TBC1D17,STX17,RPA2,CDK1,VPS4B,CFTR,CDC42,CEP97,RPGRIP1L,SCAMP2,UQCRC2,CCNF,ARF1,OPTN,FIS1,CHCHD4,PLEKHJ1,RHOB,TUFM,RAB11A,MYC,RAB2A,CTSD,ETFA,DHX9,MAP3K11,RAB1A,HSPD1,CCR1,GDI2,RPN1,TFRC,EZH2,FCF1,CD2BP2,RAP1A,CENPM,RAF1,WIF1,FHIP1B,RAB11B,NDUFS8,POLE3,RAB1B,RPL35A,EED,RAP1B,DUSP6,AGPAT1,UPK1A,AGR2,MOV10 |
| 1.494e-06 | -13.41 | PPP1R12A (protein phosphatase 1 regulatory subunit 12A) | protein interactions | 4659 | 297 | 121 | 19454 | 5460 |
MAPRE1,SH3BP5L,SPOP,PPP1CC,SMARCA5,JUNB,VIRMA,DEK,DYRK1A,SH3BGRL,ROCK1,RPGRIP1L,CTTN,TUBA1B,CCNF,PSPC1,HSP90B1,CDK1,RPA2,P3H1,RPRD1B,FTH1,CFTR,MND1,CDC42,NEK2,UBA52,TPT1,ATG16L1,KDM1A,ARPC2,RPA3,CORO6,BAP1,USP15,SNRNP70,ANKRD49,SMAD4,GAPDH,HDAC6,COPS5,ZBTB2,CDK9,PTP4A3,RPL35A,NUPR1,ACTR2,CAPZA2,CDK8,CBX3,TP53,FBP1,MRPS18C,FBXO25,TOLLIP,ERLEC1,ILK,SETD7,OSGEP,PHF7,YWHAZ,BTF3,SFN,CDKN3,HNRNPC,PSMA4,MYC,APEX1,TNPO3,FBXO22,DYNLL1,MED17,ACTB,SOST,MED23,PPP1CB,G3BP2,STAU1,EMC1,GABBR1,DDIT3,HSPA8,FOS,SPECC1L,DDX39B,ANKRD50,YWHAB,RB1CC1,CTNNB1,SIAH2,YWHAH,YWHAG,PFDN5,PIK3R1,HSP90AB1,WIF1,ATXN10,HNRNPL,WDR82,XPO5,SMARCB1,CHMP4C,RPN1,TUBB4B,PLS3,TULP3,SOX2,ACTN4,ISG15,ZNF263,HNRNPDL,COPS4,AHCYL1,IMMP2L,PFDN1,DMPK,RUVBL1,ROCK2,KRAS,BAG2,NUDT5 |
| 1.496e-06 | -13.41 | NELFCD (negative elongation factor complex member C/D) | protein interactions | 51497 | 101 | 51 | 19454 | 5460 |
PRMT5,PHF21A,ANAPC2,POLR2F,TUBA1B,GSTM4,POLR2B,APEX1,ESR2,AR,COX6B1,ATP1A1,RPS26,RIT1,LAMTOR1,YWHAZ,SQSTM1,NUP50,CDSN,KDM1A,HSCB,PHB2,HMGB1,RPS14,COX6C,PSMB1,FABP5,SRSF1,COX4I1,CCAR2,HYPK,YWHAG,YWHAH,TMBIM6,COX5A,WWP2,HAX1,SMAD4,MUL1,COX8A,UBE3A,KRAS,SEM1,NETO2,SUPT5H,TP53,RPS11,POLR2C,AAMP,OTULIN,HDAC11 |
| 1.496e-06 | -13.41 | IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon) | protein interactions | 9641 | 101 | 51 | 19454 | 5460 |
TRAF3IP2,TNFAIP3,HSP90AA1,YPEL5,PSMD14,CCT2,TRIM27,NFKBIA,FBXO22,TAX1BP1,VAMP1,TANK,EIF4B,LCP1,MAVS,BIRC2,HSPA8,APPBP2,NMRAL1,IRF3,PML,RNF11,IRF7,YWHAH,TRAF6,IKBKB,BCL10,PSMB1,WDR82,HSP90AB1,TCP1,DSTYK,TRAF2,AZI2,PPP2R1A,TRIM6,CCT5,TBK1,TOPORS,CD209,PLS3,PDIA6,RUVBL2,SIKE1,PABPC1,CCT8,MYD88,RIGI,TICAM1,ROCK2,TNF |
| 1.510e-06 | -13.40 | LSM4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 25804 | 171 | 77 | 19454 | 5460 |
XPO1,PPIB,SNRNP70,DDX23,USP15,LSM3,ALYREF,FUBP3,PRCC,RBM5,RPL32,GTF2B,SYNCRIP,SNRPD3,LSM5,TOP1,FZR1,ZNF511,WDR44,RBM42,PRPF18,FBP1,TOP3B,EXOSC8,WBP11,SOX2,SNRPE,SART3,VAC14,PQBP1,TCEA2,LSM14A,HUWE1,KRAS,RBBP7,RIGI,SSRP1,SMN1,OLA1,MEPCE,MYC,SNRPB,PRPF31,RMI2,LSM6,GEMIN8,RIT1,CCNF,ZMAT2,SGTA,SMU1,SNRPD1,PRMT5,SNRPD2,SNRNP40,SNRPB2,NMI,ESR2,SNRPN,WDR77,SF3A1,METTL14,LSM2,USP39,WTAP,KLC2,HEXIM1,RPL26L1,PRPF4,SNRPA,RPA3,DDX39B,PPIH,SF3B1,HSPA5,LSM8,COIL |
| 1.513e-06 | -13.40 | PRKAR1A (protein kinase cAMP-dependent type I regulatory subunit alpha) | protein interactions | 5573 | 300 | 122 | 19454 | 5460 |
RBFOX3,KARS1,TSNAX,MAP4,AGPAT1,WDCP,HRAS,NELL2,MCL1,PRNP,PLEKHF2,G6PD,PTP4A3,CDK4,CCT5,METTL15,EEF1A1,MAP1LC3B,ARPC3,DDX42,PSME1,SLC25A11,PALM2AKAP2,ERO1A,HNRNPK,AKAP12,MEPCE,MAT2A,AKT1,TUFM,PRKACB,CFL1,RC3H2,BAHD1,UBE2H,SMAD2,CREB1,GSK3A,ADRM1,BCCIP,DYRK1A,ROCK1,SMURF1,CAPN1,RBFOX2,FGFR1,JUP,RPA2,ACACA,RARS1,DYRK2,UBE2M,PRKCA,BAP1,KLHL28,SQSTM1,PRKCB,GTF2I,MARS1,HSPA5,FABP4,RPL6,PFDN5,STOML2,IFI16,PRKX,GSTM3,DYRK1B,XPO1,HSPB1,AHSA1,CBL,SPHK2,RPL8,DHX15,CCT7,EGLN3,HEXA,ARFGEF1,RAF1,CSNK1E,TULP3,GABARAPL1,SOX2,TRAF2,KDELR1,PLS3,CSTPP1,MOB3C,EIF1AX,CCT8,PABPC1,HIGD1C,ZBED1,KRAS,RFC2,PYCARD,CUL3,PYCR1,CUL2,MCM3,PRPF31,YWHAZ,DNAJB6,SERPINH1,SETD7,ILK,SP1,RAN,BAD,TAB1,SNRNP40,BTG3,MAT2B,PRDX3,VAPB,PAK2,EIF4B,AKAP1,DDX5,HSPA8,MCMBP |
| 1.517e-06 | -13.40 | TRIP12 (thyroid hormone receptor interactor 12) | protein interactions | 9320 | 199 | 87 | 19454 | 5460 |
RFXANK,AKR1A1,DCTN3,STAU1,RP2,HSCB,GGH,SMARCE1,RPL39,SFN,CUL2,MYC,H1-1,YWHAZ,CPSF1,LMBR1L,APEX1,TAX1BP1,FBXO22,SPCS1,SOX2,ACTN4,RAF1,TAF10,MOB3C,EZH2,KRAS,DDRGK1,YWHAH,YWHAG,RPL6,IFI16,UBXN6,GSTM3,YWHAB,SMAD9,UBE2D1,EED,OCIAD2,SRSF1,FBXO32,CEP19,CYTH4,CFTR,POLR1D,CAPN1,ATG16L1,GRM2,RPA2,LGI1,SIRT7,RPA3,FBXW7,RPL4,CERS2,KPNA6,RPL7A,ATP1A1,MECP2,PRKRA,FGFBP1,ZNF330,CCNF,VIRMA,SRPK2,NMI,DYRK1A,UBE2L3,MAP2K3,TP53,H2AJ,NUPR1,CBX3,RPL3,NAE1,MDC1,MEPCE,TOLLIP,H3C1,BRD3,KPNA1,H2AC4,ARL4D,KRR1,ALYREF,EEF1AKMT3,CDK9 |
| 1.534e-06 | -13.39 | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | REACTOME pathways | R-HSA-1234176 | 67 | 40 | 10285 | 3229 |
PSMC3,PSMD14,PSMA1,UBE2D3,ELOC,RPS27A,UBA52,PSMD4,UBB,EGLN3,PSME2,UBE2D1,PSMD10,CUL2,PSME1,PSMB4,PSMD6,SEM1,PSMB9,PSMD7,PSMA4,PSMB10,PSMA5,EGLN2,PSMB11,PSMC5,PSMB2,PSMD1,PSMA2,PSMB6,PSMA6,PSMB3,PSMB7,PSMD3,PSMB1,PSMB5,PSMA3,PSMC4,PSMC1,PSMD12 |
| 1.534e-06 | -13.39 | Asymmetric localization of PCP proteins | REACTOME pathways | R-HSA-4608870 | 67 | 40 | 10285 | 3229 |
PSMB5,PSMA3,PSMC4,PSMC1,PSMD12,PSMB7,PSMD3,DVL2,PSMB1,PARD6A,PSMB2,PSMD1,PSMB6,PSMA2,PSMA6,PSMB3,PSMA4,SMURF1,PSMB10,PSMA5,PSMB11,PSMC5,SEM1,PSMB9,PSMD7,PSME2,PSMD10,FZD4,PSME1,PSMB4,PSMD6,RPS27A,FZD3,UBA52,MIR937,PSMD4,UBB,PSMC3,PSMD14,PSMA1 |
| 1.534e-06 | -13.39 | gene expression | biological process | GO:0010467 | 2751 | 915 | 18204 | 5365 |
TWNK,SNAPC1,TCEANC2,RPP21,DRG2,IL2RG,SRPK2,KRAS,SNRPD3,DPY30,POLB,DTWD1,METAP1,GTF2H5,MRPL40,FARSA,RTCB,RP9,PIWIL2,MPDU1,RPL22,CREBBP,PROX1,NFKBIB,EIF3J,EIF2D,TTC4,QNG1,NPM3,FOSL2,AHSA1,WDR3,SNRPA1,COPS5,METTL25B,HNRNPC,SNRPE,PFDN2,CCT2,SMAD1,COIL,MACROH2A1,CDK7,CISD1,MRPL36,HSPE1,PRCP,MTF1,MRPL9,AIP,CWF19L1,SELENOF,RPL23A,TYW5,ACTMAP,CREB1,SLU7,HSPB2,HSPB1,SCNM1,TDRD7,MARS1,DNAJC19,MRPS28,SPON1,THOC2,MRPL16,PMPCA,MRPS26,HNRNPA1,WWP2,POLR3GL,EIF2S2,MED21,USP15,HSP90AA1,NFIL3,NAA50,PWP2,SNIP1,ATP6AP2,POLR2D,NAA60,FKBP1B,CBFB,HSP90AB1,CD28,RPP14,POLR3H,PRDX4,PFDN6,FCF1,RBFOX2,MRPS33,SMG5,MTG1,SNRPA,MRPS23,APOBEC3F,SNRPG,YBEY,SNRNP70,POLR2I,WBP11,RNF113A,PSEN1,EGR2,ARB2A,RPS27L,MRPS21,RBM22,ZMPSTE24,ZCRB1,MPHOSPH6,IRF9,TAF2,SMAD2,ALKBH5,BUD31,MSX1,ETF1,PPP1R1B,RPS3,EEF2,GALNT2,POLDIP3,ADIPOQ,NAA15,ZC3H15,SRSF2,SRSF8,HNRNPH3,GTPBP1,S100A10,BRIX1,CARS1,BATF,CD226,PRPF4,RPS29,MME,DFFA,KLK6,PIR,H2BC1,SPCS1,TRA2B,TFB1M,QRSL1,ANKH,OGG1,INPPL1,RPF2,FRA10AC1,TSEN34,EEF1B2,SPHK2,PPAN,HSP90B1,PPIH,BOLA2B,RPS28,HSD17B1,LMAN1,DIS3L,MTRES1,WDR83OS,KTI12,SCN2B,EIF4E2,RPS16,LDB1,VPS72,ZMAT5,PFDN1,TAF7,ERCC3,NOP9,SPPL3,FKBP8,POLR1B,DNAJC2,NONO,SEC11A,DDIT3,MRPS18A,TSEN54,FKBP10,FGFR1,SRSF1,ATXN1L,CMTR2,TBCE,PSENEN,NDUFAB1,COMT,HELT,PIWIL4,RRP7A,RPS20,NCSTN,EIF4H,RPS5,AASDHPPT,MRPL47,NR4A2,POLR2L,LSM6,MNAT1,PTGDS,EGR1,CHCHD4,IKBKB,MYRF,MKKS,LIPA,PPARG,CCNA2,RPL23,GLE1,SPCS2,CTNNB1,SLC1A1,CRTAP,RPF1,SHLD1,TSNAX,CYFIP2,RPSA,GEMIN8,EP300,DR1,MAGOH,CSTF3,NAA16,EIF3D,WDR77,POP7,HSD17B10,KARS1,LSM4,PDIA2,PRMT5,RPS27A,MRPS34,ISG20,SMAD4,GRB10,DPH3,AKAP17A,MRPS35,NOP53,GON7,POLR1D,KPNA6,EIF3G,BAD,ABCE1,TUBA1A,DDX39A,MED31,JAK2,TSR2,INTS6L,TSPAN15,CDK12,RRN3,RIC3,TRIM24,ATG4C,RIOK2,EIF2AK2,POLL,MRPS18B,ERP29,GTF2F1,VIRMA,THRAP3,ASMT,STOML2,DUOXA2,RPS17,POLR3B,RNASEL,SNRPB2,RNF14,THUMPD1,EEF1A1,MRPL11,LUC7L3,ST13,RPL39,OSGEPL1,AURKAIP1,HSPD1,MRPS7,BAP1,SNAPIN,POLR3F,MPHOSPH10,RPL26L1,HYPK,RPLP0,SRSF10,RMND1,H3C1,RPLP1,LYAR,SNAPC3,ELK1,HSPA13,RPS23,MED29,KHDC4,EIF4E3,ENPEP,WDR82,ELP6,METTL2A,MRPL22,RBFOX3,ECD,RPS2,EEF1G,ESS2,RWDD1,NGDN,SYNCRIP,CREBL2,TIA1,HNRNPD,SNRPN,TAF9,EIF4A3,ELOC,NXT2,ATG4A,CMTR1,TRMT1L,SMAD3,EIF1AX,SNRNP27,RPS7,PKNOX1,ELP3,DNAJC4,GRPEL1,TYW3,CLU,RPL19,WDR83,RPL3,MED30,EIF2S1,RPL24,NFKB1,GTF2E2,TERT,KCNJ8,PABPC1,SUPT3H,LIPT2,P3H1,MRPL33,MRPL20,CLPX,PRSS37,TFCP2,FOS,RPL32,PRSS12,HNRNPF,SNRPD2,RPAP2,MRPL18,TXNL4A,UTP23,GRM2,CD2AP,TTC1,THBD,DNAJC7,TSR3,MRPL24,NAA11,DNLZ,NDP,ELOF1,PRKRA,MEF2A,MRPL53,CPSF1,DHX38,TENT2,ZRANB2,RPL8,FAU,MED17,RBM27,PSEN2,ISCA2,TCOF1,METTL6,MRPL51,NOVA1,SNRPB,POLR2F,ATF4,POLR2G,SF3B6,HNRNPK,SQSTM1,CSTF2T,PTGES3,EXT1,SRGN,NRDE2,PPIL3,SMARCA5,PPID,EIF1B,SERPINH1,PIWIL3,DRAP1,ADGRG1,MRPL50,PDIA6,CELF6,SRSF4,EXOSC3,DNAJB4,UBL5,MECP2,SMARCB1,IVNS1ABP,NOB1,PGK1,IFI16,RPS24,TFIP11,SNAPC2,CCT5,EIF3K,EIF1AD,RPP25,NBN,METTL14,EIF2B5,GTF2IRD1,ALYREF,KRR1,PQBP1,DNAJC5,SLC30A5,IRF1,DTWD2,UTP15,TMEM208,TRMT5,ZMAT2,LTB,SUGP1,AANAT,RPL29,LTO1,EIF2B3,SMNDC1,RPRD1B,LSM2,GFM1,GTF2B,THOC3,CCR6,SF3A1,STAT6,RNF8,PRDM4,DDX4,ZNF345,ADRB2,SRSF7,ZNHIT6,DBR1,COL3A1,FKBP2,DHX9,SDF2L1,RPP25L,HSPA14,DRG1,CCS,CTU1,NHP2,FKBP1A,EIF4EBP2,TSN,BUD23,CDC5L,DHX15,PELO,PRPF19,TOPORS,CWC15,IMP4,DICER1,QTRT2,MTRF1,LSM8,SF3B5,DNAJC25,RBM23,NSA2,IL1R2,CPSF4,RPL7,SUB1,HNRNPA0,CPEB1,EXOSC4,CSNK2A1,PPIG,BAG3,PDF,ERO1A,MRPS17,SOX9,SART3,RCHY1,IFT172,RTRAF,ARMC7,PPIA,AGO1,CRYAB,SECISBP2L,SREK1IP1,DDX42,TLR3,RPS14,PELP1,GTF2F2,BARX2,TSSC4,SRSF12,OSGEP,NXT1,REN,EIF5A2,PCSK2,SWAP70,RPS9,MRPS16,CMA1,YAE1,RUVBL2,TRMO,GPBP1L1,EEF1E1,FASTKD5,THG1L,F9,SNRNP48,FURIN,RPL18,RPL17,LSM10,FXN,MRPL57,FAM98A,RPL10L,RPL37A,DGCR8,THAP1,KLHL3,HTRA2,HSPA5,PAAF1,CDC37L1,MYD88,GTF2H4,TAF5L,PDE12,PDIA3,TNF,GRPEL2,SF3B1,MED11,MRPL34,HINFP,CCT8,GTF2A2,STUB1,DNAJC10,SSU72,PLAC8,BCL6,PFDN5,RSL24D1,RPL28,CASP4,RPL6,PRPF18,CD2BP2,RSRC1,RB1,IK,NFYA,SUPT5H,LSM3,MED4,CDK9,RBM5,CASC3,NHEJ1,ABCF1,MFAP1,RP2,H2AB1,GTF3C3,NLRP3,CEBPG,SNRPD1,CNTN1,RBM38,BOLA3,EPOP,NCBP2,DDX5,RPL35,FTSJ1,ZC3H7A,DDX23,HENMT1,TRMT13,CIAO1,TP53,SPCS3,MAEL,KLF4,RBMX2,TOR1B,POLR1H,RPS15,RARS1,TLR4,USP39,IMP3,MRPS11,GEMIN7,ZNHIT3,ITGAV,CHORDC1,RPL9,ZNF473,TRIP4,EMG1,SAP18,INTS10,LARGE1,BAG2,PPIB,HSPA8,RPS26,PIWIL1,ZNF326,B2M,EIF2B2,TCEA2,GTF2I,DROSHA,CDC123,LGALS3,METAP2,WDR6,HMCES,GAPT,TRMT61A,RBM15B,RBM3,MLF1,RPL15,SNRNP40,TRA2A,PPWD1,SUV39H1,DDX46,NAA35,FYTTD1,MRPL10,NUDCD3,VDR,BAK1,APH1A,DKC1,WTAP,ENY2,MRPL23,CHCHD1,GRSF1,CALR,SIRT7,SKIC8,METTL15,MTERF2,RPS4X,EXOSC8,FUBP3,UBA52,RPL26,CCT7,PDRG1,DNAJC24,EIF4B,FKRP,SLAMF9,CEBPE,KBTBD2,ELAVL4,CLP1,AKT1,BMP1,IL1B,SRFBP1,DOHH,SMU1,PARL,DIO2,RPRD1A,PPP5C,RPL4,TAF11,NR1H2,FTSJ3,PCSK9,PAIP2,HIRA,MSH6,CYTL1,IL2,MRPL52,SOD1,AR,SNAPC5,RPL27,RPL13A,XBP1,TSPAN5,PFDN4,EIF4A2,CPE,GP9,TRAF3IP2,EIF4E,IL6,UTP6,PAIP1,LSM5,ADAT1,NOP58,DDX39B,PADI2,IMMP2L,POP5,NKX3-2,THOC6,POLR2C,MMP14,DDX1,RPL12,SF3B4,TENT4A,DUS4L,SMN1,RPLP2,COPS2,RCL1,FOXP3,ERRFI1,DHPS,RPL7A,EXOSC1,TAPBP,MED27,GTF2A1,TUFM,NCAPG2,MAD2L2,URM1,RIGI,PAX6,PAPOLA,RPL27A,WNT10B,EDNRA,HM13,DHX16,DNAJB6,RBM34,DNAJB2,CDC73,DNAJC3,RAMAC,HDAC3,RPL10,TRMT112,MED9,MRPS18C,MED23,NPC2,MRM2,CNOT6L,APEH,VSIR,XPO1,TCEA1,RBM17,FOXA3,TESC,EAF2,NOL7,INTS12,SGF29,MRPL17,PPIC,APOBEC3C,MED22,CCAR2,ZC3H11A,SELENOT,MAK16,HNRNPL,SCG5,MED10,NOC4L,PIH1D1,NPPC,RPL10A,MRTO4,GCFC2,GLRX5,RBM42,EIF5B,KIN,POLR2B,DNAJC1,WBP2,YIPF5,DPP4,RPL7L1,AKAP8L,TRMT10B,VPS54,TRMT6,PPIF,C1D,MRPL12,MRPS9,APOBEC3A,GTDC1,CCNH,MRPL13,MRPS25,RPS13,TBCEL,FKBP4,PRPF31,GFM2,THOC1,SUPT4H1,ADRM1,WDR55,RPS10,MAGOHB,WDR12,TAF10,F7,APEX1,RBMS2,NUP107,TRMT11,UTP25,BACE1,RPL35A,RBM41,HNRNPA2B1,CD40LG,GTF2H2,CHTOP,TOR2A,RPL31,SAMHD1,GTF3C4,UNC45A,HSPB6,RPS12,GTF2E1,RPS11,MRPL41,EIF3E,GTPBP2,RCE1,BCL9,TCP1,DEK,HS2ST1,NIBAN2,CAPN2,MRPL49,CDC40,TRUB1,CCDC47,PIK3R1,CUL3,CTNNBL1,CPSF2 |
| 1.552e-06 | -13.38 | negative regulation of blood vessel morphogenesis | biological process | GO:2000181 | 156 | 74 | 18204 | 5365 |
GHRL,MIR20A,MIR193A,MIR214,MIR17,MIR377,RGCC,MIR30E,MIR222,SLC12A2,GADD45A,PPARG,NIBAN2,MIR503,MIR221,CCR2,MIR212,PGK1,MIR375,MIR146A,MIR492,MIR21,MIR30B,MIR137,MIR29C,ATP2B4,CXCL10,MECP2,MIR125A,STAT1,PML,MIR16-1,HGS,GTF2I,MIR424,MIR29A,MIR205,MIR495,VASH1,PRL,MINAR1,MIR885,MIR34C,EPHA2,KLK3,KLF4,MIR10A,EMILIN1,FASLG,KRIT1,MIR939,MIR361,TNF,IL17F,SPRED1,MIR505,MIR34B,EFNA3,MIR106B,ROCK2,MIR640,MIR1298,MIR24-1,MIR185,TGFB2,SYNJ2BP,MIR145,CTNNB1,ROCK1,MIR143,AGO1,MIR15A,ADAMTS1,MIR34A |
| 1.563e-06 | -13.37 | NRP1 (neuropilin 1) | protein interactions | 8829 | 309 | 125 | 19454 | 5460 |
CSNK1A1,FDFT1,RAB6A,GINM1,TOMM22,EFHD1,PGRMC1,STX7,FXR2,ATAD1,GNA14,HADHA,CXCR4,PEBP1,RAB11A,EPS8,CBX5,GNB1,ESR2,MB21D2,RMDN3,AP2M1,SARM1,SEC61B,FGF7,VDAC2,VEGFA,NDUFA12,HGS,GNAQ,PDHA1,RAB4A,ACTN4,PCDH19,ERLIN2,TNPO2,NAA16,MARCKSL1,RAF1,TMED7,RAB18,SSRP1,TNF,ETFA,VDAC1,PLCB1,MRPS11,NDUFA4,TMEM30A,HNRNPD,C2CD2L,FGF1,FAM241A,STOML2,ICAM2,RAB5C,NUP35,LANCL1,HNRNPL,EIF2S1,KCTD10,PTK7,RAB35,FGFR1,PIP5K1A,AIF1L,NF2,CERS2,FTSJ1,ST8SIA4,TNFAIP1,RPL27,NAPA,NRP1,XPOT,AP2A1,SNX5,SORD,ATP1B3,GORASP2,RAB2A,UQCRQ,DEK,GNAI2,VIRMA,RAB14,CTSB,KCTD9,YES1,SLC25A4,CPT2,SEC61A1,SGTA,SCAMP2,DHRS7B,GNAI3,CTLA4,SURF4,GPD2,AGER,ARPC3,BCS1L,CMPK1,YTHDF2,FAM162A,TP53,FKBP8,CAMKV,TGFBR2,L1CAM,RAB3B,SLC25A10,POR,CSNK2A1,GLO1,KARS1,ILVBL,TMED9,SEMA3C,GNPAT,CDCA3,ITGA6,SRP14,ACSL4,NDUFB4 |
| 1.569e-06 | -13.37 | enzyme binding | molecular function | GO:0019899 | 2086 | 717 | 18094 | 5411 |
LILRB1,SOD1,SHC1,HSP90AA1,ATG16L1,CD28,NEFL,STAT1,CCAR2,ANKMY2,PSMD1,ANKRA2,SRC,TBK1,TRIM37,SHC3,SRSF1,SLC2A1,PGAM1,DYNLL1,PTPN1,PRKRA,ADD2,HDAC6,PEX26,MAP3K12,CST3,CAPN2,CSE1L,GTF2F1,ZNHIT6,AATF,RNF20,GOLGA7B,UBE2D3,PAX6,COL1A2,TIMP1,RALA,YWHAB,PIP5K1A,TCP1,TIRAP,IGBP1,RPS2,ILK,EHHADH,DUSP19,TAX1BP1,ACVR1B,PPME1,SOX9,PRDX3,KLF4,RFC2,MET,PRR5L,SMAD2,PEX5L,CYRIB,RPA2,NCKAP1,PTGES3,NR2E1,TSPAN15,TMEM127,GSTM3,PLG,PPP1R18,JKAMP,CUTA,STAP1,CUL2,CDK5RAP3,GOLGA5,CSTB,MOB4,SOCS5,MECP2,TRIP4,DET1,ERLIN1,TNF,EIF4E,GDI2,PPP1CB,YWHAH,UBE2N,CLU,PTPN22,PFKFB2,MAP1LC3A,DUSP22,UBASH3B,WRAP53,CDC42SE2,DNM2,CKB,STOML2,RNF8,TUBB,STAU1,CREB1,DIRAS1,PSENEN,RGCC,TNFAIP1,CDC42SE1,CNPPD1,SUMO2,SPTBN1,PIWIL1,TRIB1,NACC2,TOLLIP,PLN,UBE2K,RB1,MAD2L2,PDE6D,CASC3,FBXO7,ANAPC2,PHYHIP,CTSC,USP2,CCNB1,DUOXA2,SNX10,IRAK4,HINFP,TERC,TNFRSF1B,HPS6,PPP3R2,MACROH2A1,LDHB,TIAM1,LAMP2,ACTL9,NR1H2,PGR,BACE1,TIMP4,LTBR,RRAGA,CYFIP2,PLCB1,STK38,CDK12,ATP1B1,NDUFS2,DNAJC10,TRIM22,SUMO1,UQCRC1,EMP2,FAM83B,SPRED1,SIAH2,APOC2,LDLR,MEF2B,SART3,ATP2B4,STUB1,PRKAG1,ANKIB1,SCNM1,CHP1,EIF4E2,SVIP,ENO1,FATE1,OXSR1,CXCR4,TRIM34,RAP1A,SH3BP4,PAFAH1B1,CKS2,SRI,GSK3A,CDC42EP4,TNFRSF14,DIO2,FAF1,CSK,AVPR1B,LCP1,BCL10,RHOJ,NKX3-1,DBT,DLG1,CAV2,RPAP2,FAF2,THAP7,IL15RA,RABGGTB,LCORL,CAB39,TANK,AKT1,GNB3,TSPAN5,NEK2,MAP1LC3B,PHKG1,PRDM4,PTN,DDRGK1,GCC1,CBL,UHMK1,SEMG2,CSTA,RUVBL2,NFKBIA,TFRC,DLG3,HACD3,FBXW7,SUMO3,UFL1,ISG15,MAGEC2,CD40,TCF21,TWNK,HAPSTR1,RNF5,DCUN1D1,ARPP19,PIAS1,RANGRF,HGS,CRADD,PACRG,DIS3L,DCUN1D5,PREB,OGG1,VSIR,LIN7B,STX17,HDAC3,YWHAG,MSH6,KPNA2,RIMS3,HYAL2,CAMK2N2,ATP5F1A,MAPRE1,CDKN2C,FGD2,DERL1,RPRD1A,STX8,PPARA,ELMO2,BRMS1L,SMAD1,RHEB,ADIPOR1,SPOP,DUSP1,CHCHD3,MAF1,HACD4,MAVS,STXBP1,TOM1L1,SYVN1,ADCY2,RNF40,NOTCH2,GTF2B,CACYBP,CUL3,AP2A1,GJA1,TMSB4X,UBE2B,TAF7,MAPKAPK3,MAP2K6,GSKIP,SIT1,BAD,CD2,TNPO3,EPS8,JUP,TOPORS,PHB1,FHIT,PRKCB,CBX3,CCNA2,HDAC5,MEF2A,SPOPL,HSPA8,SLPI,GSTM2,SP2,CDK5R1,RHOBTB3,VCPKMT,SRSF2,PSMA3,CTTNBP2NL,SNAP91,RHOU,LRRC14,PRKCE,WDR44,RNF41,SERPINC1,XPO1,SNX3,HM13,TUBA1B,CCND3,EID1,H2AC13,RIMS4,CCT2,BRCA1,SMYD3,XPO5,PTPN5,MIF,GPR37,KIT,GMNN,ANP32B,TAF10,MAP3K11,MAT2B,ARF6,EXOC5,CYP1A1,SMAD5,CAV1,SNRPD3,STAT2,YES1,PSEN1,PLSCR4,PICALM,SLC6A3,PDE8A,RNF34,HACD2,AKAP12,STAT6,EGR2,RHOBTB1,HCLS1,SHPRH,CYB5A,RNF14,SUPT5H,BOK,ATG101,CDKN1A,SELL,SIKE1,RASGRP3,XRCC5,TSG101,DAAM1,MAGEA4,PPP1CC,NCSTN,BIRC5,GPIHBP1,BICD2,LMNB1,TOR1AIP2,BCL2L1,HSPB1,TRIM8,CDC42,ATP5IF1,NCK1,ATP1B3,GABARAPL2,NTRK2,PRKCA,PRNP,PYCARD,FEZ1,RNF152,SQSTM1,COPS5,LSM2,PIH1D1,CLEC6A,CBX5,NRP1,RAB29,PTEN,USP6NL,IKBKB,HSPD1,DVL2,ECD,CYRIA,ALKAL1,GRIA1,UBB,TESK1,FERMT2,H1-5,SFN,RTKN,STIM1,UBE2A,NPC2,CDC42EP2,CCNY,FZD6,MARCHF5,RND3,SIAH1,PTPN11,ANGPT1,MAPRE2,LILRB4,EXOC8,ADRB2,LGALS3,NPC1L1,RPL23,RPRD1B,EEF2,TP53,TBC1D13,NEDD8,GARRE1,LDB1,NELL2,FOXP3,EGR1,MTA2,GIT2,NOP58,CCND1,CCDC186,SERPINB9,SUFU,AKAP8L,FLOT1,FAM83A,POU5F1,CORO1C,ATF4,IPO8,SPHK2,PIK3R2,PDCD10,COTL1,RTN4,FAM20C,STX1A,GHR,KIF3B,CPSF1,ARMT1,METTL21A,PLSCR1,SLC25A5,TFPT,AGAP2,PML,ALOX5AP,PPM1D,HSPA5,PPP1R11,CRY1,AR,GCHFR,FAS,SOD2,CARHSP1,CKS1B,FAM83C,GABARAPL1,HNRNPD,ZMYM2,SERPINA1,RND2,XPOT,ZNF326,ARHGAP1,FLCN,HMGA1,UGT1A1,TULP3,LDB2,PHF1,UBE2W,GSTM4,RILPL2,CACUL1,PKIA,TICAM1,ELOF1,HSP90AB1,AGO1,NHERF1,PRKAB1,VRK1,PPP1R12A,SLC12A2,BTG1,CDC42EP3,HMGB1,MAP2K3,NAE1,JAK2,SDF2L1,UBE2L3,RRN3,CTNNB1,TRIM68,TRAF1,METTL6,ROCK2,PRDX6,RPS3,EPHA4,TOM1L2,SERPINA5,RUSC2,UBA52,RBBP4,DPP4,SMAD3,EEF1A1,BECN1,SMG5,SHOC2,RB1CC1,JAKMIP1,TFEB,JAKMIP2,HPCA,APH1A,SNTA1,CAVIN2,SYK,YWHAZ,UBE2D1,SP1,ESR2,PARD6A,SLC6A4,POLB,C9orf72,ERLIN2,TRAF6,RHOG,TRIM6,RHOH,DCUN1D3,GAS8,HSP90B1,CDK9,MAPK4,CTNNBL1,BFAR,MUL1,PPIB,JAK1,PPP3CA,ATP6V1G1,WDR45,SUPT4H1,RFXANK,CTNND1,PCNA,HINT1,TXNIP,WBP1L,ACTB,FGR,H2AX,CD4,OCRL,NEK9,PEBP1,ACTA2,TIMP3,VAPB,DAPK3,RUVBL1,GNB1,USP13,STOM,TRIM5,HEY2,CACNB4,MAPKAPK5,WDCP,BAG2,TAF9,TSPAN17,STBD1,SDC4,RNF139,SELENOS,ROCK1,RRAGB,ACVR1,HNRNPA0,SERPINB6,FURIN,MDM2,CLEC12B,EXOC2,RGP1,RPS27A,MTF1,ITGAV,RACGAP1,ANAPC4,CAV3,CFTR,TNPO2,PPP1R3C,DLG4,SPATA2,RANBP1,TESPA1,DUSP10,MCM8,RABAC1,ERRFI1,BMPR2,CD247,CDKN2D,GSTP1,RAF1,PIK3R1,UBE2I,TRPC1,DROSHA,RALB,VDAC1,PAXX,PDLIM4,FRS3,FZD4,TAB1,BRMS1,NFE2L2,RTRAF,RNF144B,VWF,SNX12,CAP2,ATG3,NLRP1,PAK2,DNAJC3,DDX5,PPP1R10,CALR,PPP1R27,CAMLG,TRAF2,TSPAN10,NXT1,NOS1AP,EHD1,NHEJ1,MSN,KDM1A,DUSP3,CD226,CDC73,TMBIM6,MTA3,TMEM106B,PPARG,COL3A1,GABARAP,CDKN1B,SPRED2,PICK1,CRKL,TRIM21,TNFAIP3,OS9,ACAT1,MEF2C,DHX9,SPDYE4,PPP2R5A,RPS7,PRKACB,GADD45A,JUN,CAMK2N1,RIGI,ADRM1,LAMTOR1,TNKS2,ABCB1,H2BC9,RFC5 |
| 1.571e-06 | -13.36 | TOR1AIP1 (torsin 1A interacting protein 1) | protein interactions | 26092 | 219 | 94 | 19454 | 5460 |
HSPA13,CBX3,MAD2L1BP,CCDC47,RAB3B,FKBP8,KLHL15,IGF1R,ESYT1,DPP4,SLC25A46,LAMP3,CSNK2A1,DNAJC1,ARF6,LMAN1,TMPO,STX6,PTPN1,AIFM1,GLT8D1,SYNCRIP,HSD17B11,RAC2,RPA2,LMNA,SSR1,MREG,CDC42,ST7,ATG4C,HSPA5,RPA3,SYVN1,DERL1,RAB9A,CHCHD4,CALU,PPP1CC,CTSB,TXN,RHOJ,VIRMA,SEC63,GXYLT1,STIM1,RPN1,RAB4A,E2F4,DNAJC25,KRAS,CA10,CYP2C9,TMT1A,RHOG,AK2,ATG9A,IFI16,LAMP2,RAB5C,DIRAS3,EGLN3,TMEM237,RAB35,GJA1,GTF2IRD1,EMC9,MAP2K1,OTULINL,RND2,SEC62,HSCB,EMC1,OXCT1,PXMP2,STX7,DNAJC22,DNAJC3,TMEM106B,AKAP1,NUP50,RAB5A,LMNB1,NTRK3,DNAJB6,COPS7A,OST4,RAB11A,MAD2L1,CHCHD3,ESR2,LMBR1L,RMDN3,SEC61B |
| 1.571e-06 | -13.36 | TMEM70 (transmembrane protein 70) | protein interactions | 54968 | 219 | 94 | 19454 | 5460 |
HSD17B10,MRPS18B,ATP5PF,MRPL52,MRPS18C,DUSP21,MRPL22,CHDH,PDE12,MRPS33,PPIF,NDUFA2,FAM162A,ATP5PB,MRPL49,NDUFS3,COX4I1,MRPS9,SDHB,MRPS23,MRPL24,ATP5PD,TNFSF18,MRPL50,FZR1,ATP5MG,COX5A,TRMT5,SLC2A1,RTN4,VIPR1,MRPL20,MRPL41,MRPL40,MRPL17,NME4,MRPS34,COX6C,PTPMT1,SLC1A1,ACAT1,MRPS28,CPT2,SLC25A4,PYCR2,RAB2A,ZMYND19,NDUFB10,NDUFAF2,MRPS16,HINT2,NDUFA4,MAEA,HSPD1,SLC25A5,MRPS17,ATP5F1D,KGD4,ETFA,ETFB,RAF1,HSDL2,NDUFA12,NDUFS6,PHB1,NDUFS8,PNPLA8,MRPL9,NDUFV2,STOML2,MRPS35,NDUFB8,MRPS26,ATP5IF1,TSPAN15,MRPS7,PHB2,NDUFS2,NDUFAF3,DUSP22,MRPL12,DHRS4,NDUFA5,ACAA2,MRPS18A,ATP5PO,MRPL13,DLST,TACO1,NDUFAF4,CHCHD3,ATP5F1B,MRPL23,MRPS25 |
| 1.576e-06 | -13.36 | RHOD (ras homolog family member D) | protein interactions | 29984 | 570 | 211 | 19454 | 5460 |
VAMP8,KRAS,SLC20A2,ROCK2,MYO1B,EFNB1,CDK5,SEC11A,BCL7B,TMEM87A,SNAPIN,STBD1,VAMP7,STX5,RAB35,ARHGAP5,PPFIBP1,CTNNB1,TBC1D5,DDRGK1,PTDSS1,ITGAV,PACSIN3,ABCC5,EMC1,ADRB2,MAP2K1,USP6NL,GOSR2,BET1,ESR2,ATP6AP2,NCKAP1,FAM83B,EFHD2,SLC38A1,SPCS3,LAMTOR1,PSMD1,STX16,SLC6A8,FKBP8,AKAP12,NEDD8,CSE1L,SRPRB,SLC16A1,STX18,ABCE1,PALM2AKAP2,EXOC3,TFRC,CCM2,BMPR2,ARPC3,ACVR1,ARHGAP12,SNAP29,PREB,LMAN1,TMPO,SLC38A2,VTI1B,ARL6IP5,FCHO2,FLRT2,RAP1B,SLC39A10,ADD1,STT3A,ITGA6,CAMLG,SMAD4,SLITRK5,CLDND1,AIF1L,RAB9A,GIT2,LEMD3,CSNK1G3,SSR1,CDC42,SPTBN1,ROCK1,STX10,MACROH2A1,NECTIN2,ATP1A1,ATP1B3,DNAJC10,ARHGAP21,GORASP2,SLC6A6,RAB2A,SLC25A1,MCM6,FLOT1,SSRP1,AHCYL1,EMC8,SLC39A7,HINT2,STIM1,RPN1,PCDH17,FAF2,PPP2R1A,MACO1,EMC10,PPIA,RAB11B,TMEM237,OCRL,SPTAN1,XPO5,CETN3,WDR6,PHB1,WDR11,RAB32,PIK3R1,STX7,NSFL1C,EXD2,NDUFA5,VAPB,ETF1,NOTCH2,DAAM1,CHCHD3,PRDX2,LRRC8A,REEP4,LAMTOR3,SPCS1,GPR89A,FAM91A1,SCFD1,SLC7A11,LMNB1,MYO6,MRPL16,TOMM40,NIBAN2,PKP4,CTNND1,ADD2,SNAP23,EMC2,RAB1A,EHD4,NSDHL,DLG1,CASK,DHRS7B,KRIT1,MTARC2,LBR,SLC29A1,CCDC47,CMPK1,CAV1,C2CD2,CDCA3,PTPN1,SRPRA,HRAS,HACD3,EHBP1,OSBPL8,SLC2A1,POR,ESYT1,RAB23,DAG1,RELL1,BMPR1B,EMC4,CDC42EP4,TMEM209,NF2,YKT6,SLC7A1,PIK3R2,MTDH,ARPC2,MAVS,ITGA2,LRRC8D,CTDSP1,JUP,PICALM,STOM,SLC12A2,EIF3J,RABL3,SEC22B,ARHGAP1,SH3BP4,FERMT2,SEC63,TMOD3,YES1,SLC11A2,GAB1,VAMP3,CTNNA1,TUBA1B,EPHA2,SMAD2,DEPDC1B |
| 1.580e-06 | -13.36 | TLR4 (toll like receptor 4) | protein interactions | 7099 | 54 | 32 | 19454 | 5460 |
TRAF6,BCL10,LY96,RBFOX3,USP13,MFN1,CNPY4,TLR1,CAV1,SRC,STUB1,TRIM44,SMAD3,HSP90B1,TLR5,HGS,PPP4C,CD14,TBK1,SYK,TIRAP,HMGB1,TOLLIP,SERTAD1,RNF115,IRAK4,TICAM2,TICAM1,PIK3AP1,RAB1A,MYD88,HSPA8 |
| 1.591e-06 | -13.35 | ZMPSTE24 (zinc metallopeptidase STE24) | protein interactions | 10269 | 141 | 66 | 19454 | 5460 |
OPTN,CYB5R3,COPZ2,SEC61B,MGST3,VIRMA,NDUFB7,MORF4L1,BAG3,TMEM196,CYP1A1,RPA3,MME,TMEM106B,AKAP1,PMAIP1,DNAL4,EMC1,MRPL40,H1-5,PGRMC1,OTULINL,SEC62,ST7,VAPB,RPA2,ARMCX3,KCNA2,PTPN1,HSD17B11,ANKRD46,RPL35A,MARCHF4,FAM118B,PRELID1,WIF1,SYNJ2BP,IFI16,RAB5C,FAM20C,EMC4,MED21,AGR2,RB1CC1,STX8,CYP2C9,MYO1B,SLC39A3,EMC2,COX8A,HNRNPF,FGF12,VDAC1,S100A10,TOMM6,GALNT2,RNF26,TP53,CENPM,ISG15,GTF2E2,NRM,RPN1,CAPZA2,IL7,VAC14 |
| 1.605e-06 | -13.34 | regulation of viral life cycle | biological process | GO:1903900 | 143 | 69 | 18204 | 5365 |
RNASEL,TRIM68,SRPK2,CCL5,CD209,TNF,CXCL8,VAPB,DDX5,TRIM62,PPIA,PDE12,VPS4A,LAMP3,APOBEC3G,TRIM8,TRIM6,RSAD2,STAU1,INPP5K,MX1,PPID,HMGB1,TRIM34,HS3ST5,CH25H,TOP2B,MORC2,APOBEC3D,APOBEC3C,PROX1,TRIM21,NECTIN2,TRIM5,ISG20,ISG15,MAVS,TMEM39A,BST2,CNOT7,TRIM15,APOBEC3B,FURIN,TSG101,KPNA2,TRIM11,IFNB1,PABPC1,OAS1,KPNA6,CD28,SNX3,EIF2AK2,HACD3,IFIH1,TRIM22,APOBEC3A,TRIM10,SLPI,TRIM26,CSNK2B,PLSCR1,CD4,IFNA2,BANF1,APOBEC3H,IFI16,PPIH,APOBEC3F |
| 1.637e-06 | -13.32 | MAFB (MAF bZIP transcription factor B) | protein interactions | 9935 | 245 | 103 | 19454 | 5460 |
COPS5,CSNK2A1,TMA16,CMSS1,MRPS9,KRR1,RBM42,DKC1,CDC5L,MRPS23,RPL35A,TOP1,RPL15,STRBP,YTHDF2,MRPL11,RPSA,MRPL47,HOXD12,CBX3,RBM34,MRPS18B,DHX9,NKRF,DLG1,SLC25A11,OLA1,RIGI,RPL17,HUWE1,BACH1,KPNA2,SMARCA5,ATF4,PIP4K2C,MRPS28,MRPS21,LUC7L3,MRPS34,LIN7C,PPM1G,IRF3,PRPF4,NHP2,BRIX1,IRF7,RPL4,MRPL41,YWHAG,DDX50,HMGA1,MRPS35,MRPS26,COPS2,HP1BP3,RPL9,NOP58,EIF2S1,LYAR,RPL7,PPP2R1A,JUN,RPL18,SART3,MRPS11,PPAN,MRPS17,SRSF4,AHCYL1,RFC2,HNRNPDL,RFC3,PAX6,COPS4,PSMA1,ADO,RFC5,NOP16,CIRBP,CHTOP,ZCRB1,MRPS25,LRRC1,SF3B4,FAU,SNRPB2,USP5,RPL7L1,TRMT112,KCTD12,ZFP64,CCDC86,SNRPA,RFC4,PYM1,RPS28,UPF3B,FOS,GINS3,MRPS7,SRSF2,FXR2,STAU1 |
| 1.639e-06 | -13.32 | STX4 (syntaxin 4) | protein interactions | 6810 | 423 | 163 | 19454 | 5460 |
MACO1,TOP3B,STBD1,MARCKSL1,E2F4,FAF2,IFNGR1,VAMP2,STIM1,RAB4A,STX12,PLD3,RINT1,EFNB1,EMC8,KRAS,SLC20A2,SEMA4C,VAMP8,RETREG1,PPFIBP1,DDRGK1,SYT4,CDK5RAP3,STX1A,WDR6,TRAF3IP3,NEO1,NRSN1,GJA1,STX5,SPTAN1,RAMP3,VAMP7,SLMAP,WDR44,GJC1,TOR1AIP2,GOSR2,PGRMC1,BET1,NOTCH2,SEC22A,VAMP1,STXBP1,VAPB,TSPAN15,TACR1,PSMA3,TMEM203,PMAIP1,RAB5A,UFL1,NSFL1C,STX7,RNF11,NIBAN2,VEZT,RAB11A,PKP4,STX16,RHOB,LMNB1,SCFD1,SLC38A1,FAXDC2,ARF1,FAM91A1,FAM83B,MB21D2,ACTB,PREB,CCDC47,UBL4A,TBK1,SNAP29,CENPM,UBIAD1,SLC29A1,LBR,TFRC,NSDHL,STX8,PALM2AKAP2,SLC25A10,DLG1,STX18,SLC16A1,CYBRD1,SNAP23,STX11,SLC6A8,CTNND1,FKBP8,TMEM199,ATP1B1,POR,ESYT1,OSBPL8,HRAS,SRPRA,PTPN1,EHBP1,CAMLG,SLC39A10,RAC2,CDCA3,PLPPR1,SPPL3,DNAJC1,VTI1B,ANKRD46,SNAP25,STX6,TMPO,SLC38A2,ARHGAP1,SEC22B,UBA52,CDC42,PTP4A2,JUP,LMNA,SLC12A2,TMX4,SSR1,GOLGA5,USE1,SH3GLB2,HECTD1,LEMD3,TEX264,ITM2B,RTN4,DPAGT1,MTDH,SLC7A1,LPAR1,TMEM209,VPS39,KCNQ5,VAMP5,GORASP2,SLC6A6,DNAJC5,HMOX2,STXBP6,CCDC22,ARFGAP3,ATP1A1,NAPA,EPHA2,PLP1,GAB1,VAMP3,ATL1,NECTIN2,SRP54,STX10,YES1,RHOJ,FERMT2,SEC63 |
| 1.641e-06 | -13.32 | CCND2 (cyclin D2) | protein interactions | 894 | 152 | 70 | 19454 | 5460 |
TUBB4B,CBX3,PIK3CA,PSMC3,RPSA,CDK4,RAF1,MAP2K3,CSE1L,SERTAD1,PSMD12,CDKN2C,SEPTIN7,CDK5,PCNA,PSMD10,H2AC4,BECN1,HSPB1,CDKN1B,PFDN5,PSMD3,API5,GRM1,LSM5,SNRPD3,FZR1,MAP2K6,PSME2,RB1,CDK6,CDK1,MET,CCND1,DMTF1,PSMC4,ETF1,CDKN1A,CDK7,KDELR2,ADRB2,NF2,HSCB,BCL6,PSMC1,SPECC1L,RPA3,PCGF2,PSMA3,TERT,H2AZ2,H1-1,PFDN2,EPHA2,STK11,AKT1,ST13,RUNX1,ACTB,TMOD3,ATP5F1B,COPE,STAT5A,UBA3,PSMB6,TUBA1B,S100A6,PTEN,SGTA,PSMC5 |
| 1.654e-06 | -13.31 | SEC61A1 (SEC61 translocon subunit alpha 1) | protein interactions | 29927 | 205 | 89 | 19454 | 5460 |
RAF1,RPS11,SEC61G,EZH2,FLOT1,KRAS,TNF,DDRGK1,PTPN5,PDIA3,ATG9A,MED4,RB1CC1,FBXO32,CSNK1A1,NMRAL1,HSPA8,TMEM106B,EXD2,UPF3B,JAGN1,COIL,ADRB2,SSR3,STAU1,CUL3,MYC,RIT1,ILK,RPS5,NTRK3,YWHAZ,LAMTOR1,SEC61B,LMBR1L,RPL19,RPL35,TP53,CCDC47,SRP72,FURIN,TFRC,IGF1R,RPL3,SLC16A1,MAP1B,MDC1,RPL17,SOCS2,SRPRB,NUP107,FAM20C,NFKB1,DPP4,MOV10,STYK1,ESYT1,PTPN1,RBM42,DERL2,CGAS,RPS16,CDK7,CFTR,RPS14,MET,GRM2,RPA2,DERL1,SYVN1,NCDN,RPA3,HSPA5,RPL4,RPS15,RPL26,SLC25A1,UBE2H,NRP1,RC3H2,PTEN,SEC61A1,PSPC1,UQCRC2,CCNF,SEC63,TECR,RPL13A,NDN |
| 1.673e-06 | -13.30 | regulation of immune system process | biological process | GO:0002682 | 1584 | 549 | 18204 | 5365 |
TOX,GPX1,CCL24,KLK5,SHLD1,TNFAIP3,CTNNB1,CALR,SKIC8,KARS1,IGF1,NFKBIA,EP300,ITGA2,SELENOS,TLR6,NCR3,IL1B,MIR136,TGFB3,AKT1,NOP53,PPP3CA,TAPBPL,BAD,PRKCE,LACC1,CCL28,PLA2G5,TIRAP,BST2,MIR125A,NR1H2,ACP5,STAT1,STX7,STXBP1,JAK2,MSN,LAT2,CRKL,CNR1,UBE2N,CARTPT,SOD1,KLRD1,FCAR,PAK2,MIR221,MIR130A,IL2,TGFBR2,TSC22D3,KIT,EIF2AK2,CD14,SIAE,TNFSF13,XBP1,CD59,PADI2,BGLAP,CD86,PYDC2,IL6,RSAD2,CSK,SPG21,USP38,ZBTB2,BAX,SLC7A1,MMP14,IL12B,FCER1G,DDX1,MIR185,POLR3B,ELF1,FGR,UBE2K,MIR223,STOML2,FOXP1,VEGFC,KLHL25,PELI1,FLOT1,GPR137,SMARCE1,HAX1,OXSR1,PRNP,MATR3,DHPS,LDLR,HSPD1,FOXP3,CD274,PNP,JUNB,CD79B,ACTL6A,FERRY3,CD80,CD36,POLR3F,WNT10B,VAV2,NMI,SERPINB9,ZBTB33,CLEC6A,SIN3A,RIGI,MAD2L2,LYAR,CD9,MIR21,MIR30B,IFNA2,INHA,CDC73,LCP2,SFN,LILRA2,LST1,RGCC,CD99L2,SH2D1A,ZBTB16,RTN4,PLCB1,IFNK,TLR9,TNFRSF1B,SMARCD3,TFRC,YES1,GPR171,BIRC2,DUSP1,SELENOK,TRIM62,MED23,KMT5B,PDCD1,PIK3AP1,CCN3,TRIM32,RHBDD3,KLRC2,GPAM,DUSP22,MIR24-1,SMAD3,SARM1,VSIR,SLC7A11,CD2,STAP1,TRIM5,PSMA1,CREB3,STK11,TESC,S100A8,FCGR2B,FBXW7,NFKBIL1,TMBIM6,OTULIN,KLF10,CD40,ACVR1B,NLRP1,SYK,CLU,PITHD1,CACNB4,NFKB1,KCNJ8,IL15RA,FUT9,ARG2,HCLS1,FOS,PSPC1,CCL2,MAP2K6,TASL,IL2RA,NINJ1,CTLA4,ZBTB39,ADGRE2,TRIB1,TBK1,CYRIB,XRCC5,SFTPD,EEIG1,CCL19,TLR5,VAMP3,DPP4,TICAM2,MIR222,TLR10,CD1B,ZBTB25,TLR2,RARRES2,TRAF6,CLEC12B,CD2AP,CD38,LGR4,HOXB8,P2RY12,TCIM,IFNG,ICAM1,IL17F,CD47,PIK3CA,F7,RNF41,SQSTM1,CD40LG,LEP,CD1A,TRIM21,MIR140,PDE4B,NECTIN2,CD200,THY1,FGL2,HEXIM1,PHB2,PSMB4,ANGPT1,SRC,TMEM176B,IL18,MMP28,EXOSC3,UBASH3B,LPXN,MOG,SAMHD1,RNF115,TFE3,VEGFA,SEMA7A,IL23A,LILRA1,SMARCB1,PRELID1,MIR181C,SIT1,FBXO7,TICAM1,NFE2L2,IL15,TLR1,PRMT6,EIF2B5,CTNNBIP1,TNFRSF9,BPIFB1,IFI16,TLR8,CCL1,YWHAZ,PQBP1,TRIM3,IRF1,ZNRF1,PIK3R1,IL2RG,NCK1,EIF2B3,RAB29,FGF10,TGFB2,IL1A,DUSP3,CLPB,PIANP,FCN2,CD209,NOTCH2,GREM1,HCFC2,CCL20,ADTRP,TNFSF18,CREBBP,ISG15,KLK3,STAT6,CCR7,CCR6,C1QC,TRAFD1,VAMP8,DHX9,PTPN22,WASL,COL3A1,OAS1,TRAF3IP3,TMEM176A,FCGR1A,PRKCB,CCR1,LTA,FOSL2,TOB2,ZBTB26,MIR708,ING5,TLR7,IRF7,FKBP1A,NLRP6,MIR200C,IL5,CD200R1,DLG1,DNAJB9,BANF1,LITAF,EFNB1,BECN1,SNAI2,IFI35,SOX9,STAT2,NDFIP1,FAM3A,CCL21,MIR20A,HCST,MIR142,GPR17,CREB1,SFRP1,MYC,LRRC14,SOS2,TLR3,DEFB124,CCL5,GPSM3,TNFSF8,RNF34,USP15,IRF3,HSP90AA1,BTN2A2,IL6ST,LILRB1,BCL10,HTR2A,DDT,IL12A,MIF,CCL3,CD83,SASH3,LYPLAL1,MSTN,MEF2C,CBFB,TAX1BP1,CD28,SWAP70,BLOC1S3,FURIN,MEAF6,RC3H2,ZBTB17,MAVS,TAB1,TYROBP,CAV1,CPTP,TRIM11,IFNB1,NCR3LG1,MIR146A,PSEN1,LILRB4,CD81,CD4,PLPP6,PTN,CD46,AQP3,MIR149,IL4,TACR1,TCTA,MYD88,RUNX1,SOCS5,IL20RB,GFI1,IFIH1,PHB1,RPS3,LY96,TRIM6,VAMP7,TRAF2,CX3CR1,MIR145,TESPA1,FCGR2A,XCL1,MUL1,IL10,CX3CL1,CACNB3,SLC39A10,ADIPOQ,TNF,TWSG1,ACTB,BATF,DUSP10,CD226,MZB1,MAPK10,AGER,PYCARD,HRAS,GABPA,EMILIN1,BCL6,CXCL12,HFE,ABHD17A,MBL2,CD1D,HMGB1,YTHDF1,RB1,NPY5R,CGAS,TBC1D10C,ZBTB45,RAG1,CDKN1A,SPHK2,MIR105-1,LSM14A,INPPL1,ICOS,TNFRSF14,CXCL10,RHOH,MAPKAPK3,TMEM126A,PLSCR1,PDCD1LG2,AIF1,CCR2,IRF4,TIFA,CD1C,LDB1,NLRP3,CCL25,EIF4E2,MIR17,PRKCA,CHST2,CXCR3,IL13,NEK7,MIR34A,CLEC7A,IL21,TNFAIP6,MITF,MADCAM1,SPPL3,CTSC,IDO1,CD1E,CXCL8,SDC4,ACTL6B,MPP1,TLR4,TRIM27,NONO,CDK6,SEC14L1,PTPN11,CCL8,MICB,ST3GAL4,TOMM70,HSPA8,PTPN1,ADORA1,LILRA3,RAC2,PRDX2,PLPP4,NKAP,DROSHA,CHRNB2,ITK,EIF2B2,ATAT1,IL7,B2M,YTHDF2,TRIM15,CNOT7,RBCK1,IKBKB,IL34,EPO,HMCES,LGALS3,CD247,CSNK1A1,PTGER4,PPARG,SLC15A2,CXCL13,FCMR,LIPA,FAXDC2,IRAK4,GPNMB,SLA2,PRKCQ,TNFAIP8L2,CD3G,UFD1,ZBTB6 |
| 1.681e-06 | -13.30 | NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6) | protein interactions | 4726 | 225 | 96 | 19454 | 5460 |
NDUFC2,GFM1,GID4,GID8,CRYZ,PDHB,SLC25A51,UQCRC1,NDUFAB1,PCK2,OR4S2,MPV17,MTRES1,METTL2A,RPS12,LIG3,RALA,TUFM,NDUFB10,ZMYND19,DNAJC19,UBE2H,SFXN1,FASTKD5,RIGI,NEDD8,RASL10B,DNAJC30,AURKAIP1,METTL15,NDUFA2,MRPL11,GFM2,SLC25A24,NDUFS3,MAD2L1BP,NDUFA1,SSBP1,AIFM1,NDUFB4,COX4I1,DBT,PRNP,GRSF1,MOV10,TMEM70,CHCHD1,TACR1,NGRN,BOLA3,EXD2,RANBP10,NDUFS2,HSCB,NDUFA5,VAPB,TACO1,CCDC90B,MAD2L1,PARL,ATP5F1B,NDUFB6,COX6B1,NDUFB7,MTG2,AUH,PMPCA,HTRA2,MKLN1,HINT2,COX8A,HSPD1,NDUFB5,PREPL,NDUFA4,MAEA,FLOT1,IMMP2L,HSDL2,CRELD1,FAM136A,NDUFA12,PDHA1,GATD3,FAHD1,PHB1,NDUFS8,COX14,RMND1,DYNC1I2,NDUFV2,MTRF1,MRPS26,NDUFB8,ARMC8,RHOG |
| 1.688e-06 | -13.29 | p53-Independent G1/S DNA damage checkpoint | REACTOME pathways | R-HSA-69613 | 54 | 34 | 10285 | 3229 |
UBA52,RPS27A,PSMD4,UBB,PSMC3,PSMD14,PSMA1,PSMB9,SEM1,PSMD7,PSME2,PSMD10,PSMD6,PSME1,PSMB4,PSMD1,PSMB2,PSMA2,PSMB6,PSMB3,PSMA6,PSMA4,PSMB11,PSMC5,PSMB10,PSMA5,PSMA3,PSMB5,PSMD12,PSMC4,PSMC1,PSMD3,PSMB7,PSMB1 |
| 1.688e-06 | -13.29 | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | REACTOME pathways | R-HSA-69601 | 54 | 34 | 10285 | 3229 |
PSMC1,PSMC4,PSMD12,PSMB5,PSMA3,PSMB1,PSMB7,PSMD3,PSMA6,PSMB3,PSMA2,PSMB6,PSMB2,PSMD1,PSMA5,PSMB10,PSMC5,PSMB11,PSMA4,PSMD7,SEM1,PSMB9,PSMB4,PSME1,PSMD6,PSMD10,PSME2,UBB,PSMD4,RPS27A,UBA52,PSMA1,PSMD14,PSMC3 |
| 1.688e-06 | -13.29 | p53-Independent DNA Damage Response | REACTOME pathways | R-HSA-69610 | 54 | 34 | 10285 | 3229 |
UBB,PSMD4,UBA52,RPS27A,PSMA1,PSMD14,PSMC3,PSMD7,PSMB9,SEM1,PSMD6,PSMB4,PSME1,PSME2,PSMD10,PSMB3,PSMA6,PSMB6,PSMA2,PSMD1,PSMB2,PSMC5,PSMB11,PSMB10,PSMA5,PSMA4,PSMD12,PSMC1,PSMC4,PSMA3,PSMB5,PSMB1,PSMD3,PSMB7 |
| 1.702e-06 | -13.28 | SRSF11 (serine and arginine rich splicing factor 11) | protein interactions | 9295 | 191 | 84 | 19454 | 5460 |
METTL14,USP39,TOX4,PAK5,RPA2,SDCBP,TRMT112,HEXIM1,ZC3H14,TANK,LNX2,RBM22,SRSF2,TRA2B,UFL1,SAP18,SNRPA,DDX46,RPA3,MME,RNF113A,EP300,CLK1,RC3H2,FYTTD1,PPIG,UBE2H,RIT1,CUL3,MYC,BRAP,H2BC9,ADRM1,SRPK2,CCNF,SF3B6,SMU1,CHMP4C,IK,NUPR1,ZRANB2,E2F4,TPBG,RAF1,CD2BP2,NCSTN,EEF1A1,HNRNPK,THRAP3,RUVBL1,TOLLIP,ATP5F1D,TFPI,ZNF592,RIGI,PAX6,SRSF4,SRSF12,ARGLU1,SRSF7,EWSR1,SNRNP70,DDX23,CRBN,ZCCHC10,PPP2R5A,PRPF19,IFI16,ZNF207,DDRGK1,TRA2A,CSNK2A1,YWHAG,TOP1,SPPL3,HNRNPL,CAND1,DHX15,SRSF10,MDM2,SRSF1,PHB1,FOLR1,CDK6 |
| 1.708e-06 | -13.28 | PRKDC (protein kinase, DNA-activated, catalytic subunit) | protein interactions | 5591 | 661 | 240 | 19454 | 5460 |
DLST,LMBR1L,ANAPC2,SF3B4,TRIM29,MATR3,APEX1,HNRNPC,MYC,BAG3,BTF3,ATG101,RBBP8,H1-1,THOC6,XRCC5,BMPR1A,SNRPA,DDX5,RAB5A,EP300,HDAC5,HSPA8,SF3B1,ADRB2,STAU1,SRSF2,TRA2B,EMC1,UFL1,MTF1,UBAC2,CSNK1A1,PIH1D1,SRSF1,EED,SNRPD3,SNRPA1,SUMO2,EIF2S1,PGR,HSP90AB1,ELK1,WWP2,MAPK4,DDRGK1,CTNNB1,YWHAG,AGR2,IKBKB,HSPB1,MGMT,POU5F1,RTCB,RUVBL2,RUVBL1,PELI1,CBLL1,DHX38,TOP3B,MAX,ISG15,HDAC11,MOB3C,MTA2,DCLRE1C,SF3B6,EIF2S2,SRP54,CTSB,KCTD9,ROCK1,SUB1,CCNB1,SMARCA5,SLC25A1,AKT1,PRKACB,UBE2H,ATP1A1,NBN,ARHGEF6,BAP1,RNF113A,STK38,HDAC3,HSPA5,CFTR,CDC42,GABRA1,WWP1,RPA2,HEXIM1,DYRK2,CD274,COQ8A,FZR1,CDC5L,TMPO,TSPO,DPP4,E4F1,COPS5,CSNK2A1,H2AC4,BECN1,SHC1,MAP4,MAP1B,SNIP1,DHX9,TOLLIP,NUP107,H3C1,FKBP8,CDK4,CHRM3,TP53,KBTBD4,MGARP,H2AX,TFCP2,BIRC5,NUPR1,RNF8,FURIN,BAD,SEC61B,SNRPD1,AP2M1,SNRPD2,USP5,GPR17,CUL3,NFYA,BRCA1,ILK,SP1,NTRK3,PAXX,HSP90AA1,C1D,CRY1,SLC15A1,UCHL3,UNC45A,TACR3,FAM234A,ACTL6A,NPY2R,EHD1,PHB1,NUP35,EGLN3,SRSF10,PRPF19,PRDX1,HMGA1,UBXN6,HNRNPA1,P2RY10,BCL2L1,AHSA1,AKT2,NUDT5,ZC3H7A,PCNA,TRIM37,RFC2,SAR1B,RAD21,SSRP1,B3GNT2,NAA15,LGR4,JUN,FAF2,PRKAG1,CHMP4C,EZH2,RPS11,CHRM4,CCNF,UBE2I,PTEN,RTRAF,GSK3A,COPE,VIRMA,AR,USP14,CDC73,HOXC4,SMAD2,SIRT7,HELLS,RPA3,CLK1,NUCKS1,FBXW7,HMGB1,DGCR8,GTF2I,ATG4C,NFYB,FAM161A,TPT1,METTL14,GRM2,JUP,LMNA,TTI2,NHEJ1,ARL10,H2AZ1,SRP14,DFFA,SMAD3,DCK,TES,IL18,TOP1,CWC15,CDK9,CALR,HDAC6,STYK1,DNAJC7,EMC2,IGF1R,POLL,VRK1,CD80,PTGES3,MSH6,MDC1,RNF20,FBP1,TNFAIP8L1,ILF2 |
| 1.711e-06 | -13.28 | PRDX3 (peroxiredoxin 3) | protein interactions | 10935 | 283 | 116 | 19454 | 5460 |
CDC42,MTRES1,UBE2M,PARD6A,HEXIM1,RARS1,METTL14,PTP4A2,ZMYM6,RPA2,GFM1,ARHGEF6,BAP1,RPA3,HSPA5,NUCKS1,FBXW7,GTF2I,GORASP2,TUFM,ATP5F1A,CCNB1,RNASET2,CARS1,MAT2A,UBE2H,SPOP,PTEN,EIF2AK2,UQCRC2,CCNF,SLC25A4,TXN,COPE,H2AX,AURKAIP1,AP1S2,TFCP2,HSD17B10,GNG5,SFXN1,ATP5PF,PSME1,RAB1A,PRDX4,ELOC,DAG1,COPS5,ATP5MG,PGAM1,CALR,KARS1,PSMB1,CD274,PRNP,DCUN1D1,PRDX3,DHRS4,PIH1D1,SLC25A3,ARMCX3,ATP5PO,HADHA,DDX5,HDAC5,BIRC2,HSPA8,PEBP1,SNRPA,UFL1,EMC1,GGH,PSMA4,CUL2,CUL3,PMPCA,AUH,MYC,ICAM1,SMU1,DLST,CYB5R3,ACTB,PRDX2,ATP5F1B,EEF2,CYB5R1,RAF1,PDHA1,CHMP4C,PCNA,PABPC1,HSPD1,ANP32B,IMMP2L,FANCG,VDAC1,DDRGK1,PPIB,WWP2,PDIA3,GSTM3,PRDX1,YWHAB,MRPS26,HNRNPD,POU5F1,AGR2,FKBP4,RHOG,IKBKB,GATD3,PSMB5,PHB1,EGLN3,SUMO2 |
| 1.715e-06 | -13.28 | MOB3C (MOB kinase activator 3C) | protein interactions | 148932 | 363 | 143 | 19454 | 5460 |
DDX1,WDR12,FKBP4,XPO1,CTNNB1,NT5C2,PRPF19,PSMD3,PEG10,HSP90AB1,CCT7,EIF2S1,CCAR2,DYNC1I2,SNRPA1,TYMS,MAGED2,ATP6V1A,RAB35,PSMB4,PPP2CB,PSMB5,MTA2,SART3,FAF2,PPP2R1A,SUPT5H,PFDN1,PSMD12,MCM6,RFC3,COPS4,RWDD4,PSMA2,KRAS,G3BP1,RUVBL1,S100A10,RUVBL2,PICK1,PCNA,RTCB,BAG2,CCT8,HSP90AA1,PFDN2,PFDN6,CKB,YWHAZ,PSMD14,SMARCE1,BTF3,JPT1,PSMD1,MCM4,MCM3,LDHB,PSMA4,PSMB6,POLR2B,MAT2B,SIAH1,PSMD6,NUFIP2,PAK2,ACTL6A,PGRMC1,COIL,RPP14,PSMC1,G3BP2,SKP1,MRPS7,UFL1,NOP53,MIA2,PSMA3,RFC4,DNAJC7,USP15,MAP4,POR,PSMD7,ESYT1,ELOC,GAPDH,MFN1,KARS1,ILVBL,TMPO,CDK9,CDC5L,CAV1,CDK6,SRPRA,PSMC3,SRP72,CBX3,TFCP2,NDUFS3,ACTR1A,CTNND1,RNF20,FKBP8,MSH6,RDH11,PSMA5,HUWE1,CSE1L,SEPTIN7,CDKN2AIP,FBXO7,GMPS,ST13,CABCOCO1,CIAO1,RPP25,FERMT2,PDCD5,LDHA,RAB14,BUB3,COPE,RPP25L,PSMC5,EIF2S2,VAMP3,SF3B6,CTNNA1,ENO1,PSMA6,POP7,RARS1,ACACA,JUP,CDK1,SIPA1L1,GTF3C4,PSMC4,MARS1,KDM1A,HMGB1,SMC4 |
| 1.715e-06 | -13.28 | MAP3K7 (mitogen-activated protein kinase kinase kinase 7) | protein interactions | 6885 | 363 | 143 | 19454 | 5460 |
APEX1,ESR2,PPP5C,NDFIP1,TAB1,TRIM29,BST2,NFKBIA,LMBR1L,FAM177A1,MDH1,HSP90AA1,FBXW11,PELI3,PYCARD,SKP1,FBXO30,UFL1,DR1,THBS3,TRIM5,FOS,HIRA,PEBP1,TIRAP,PRDX3,DAAM1,FBXO42,PRKAB1,SYK,HSP90AB1,EGLN3,ZNF593,PRKCQ,KCTD10,COPS7B,TNFAIP8L2,TNIK,HSPB1,MED4,AHSA1,PPM1B,TRAF6,FKBP4,AK2,IKBKB,MAP3K14,XPO1,PPIB,YWHAH,TRIM8,WWP2,PDIA3,SIVA1,RUVBL1,VDAC1,ETFA,TNF,BAG2,PCNA,HGS,FBXL3,NDUFS6,GDI2,EZH2,EEF2,ISG15,PPP2R1A,TRAF2,E2F4,MARCKSL1,PDCD5,MAP3K3,BUB3,PNP,ACAT1,MSN,TRIM27,TMEM74,TNFRSF1B,EIF2AK2,STUB1,CCNF,OPTN,RBM7,UBE2H,OAT,TADA3,TRIM23,TUFM,MTPN,TRAF3IP2,SUB1,EMILIN1,HSPA14,HSPA5,MRPL20,TOMM20,USP8,FBXW7,HMGB1,SGF29,MAVS,PRDX6,PGK1,BAP1,SOD1,UBE2M,HSP90B1,RPA2,PRMT2,ESD,TMPO,POLE3,TRIM45,MAP2K6,SMAD3,USP15,BCL10,MUL1,CRBN,TPM3,GLO1,COPS5,HDAC6,PGAM1,USP2,CALR,STRADB,CAPZA1,POLE4,RBCK1,HSPE1,TGFBR2,HINT1,HSD17B10,HAPSTR1,MYD88,PSMC3,TAB2,SOD2,TLR3,SOCS3 |
| 1.717e-06 | -13.27 | LYAR (Ly1 antibody reactive) | protein interactions | 55646 | 366 | 144 | 19454 | 5460 |
BET1,SYK,PIH1D1,SDC2,EP300,RAB5A,SNRPA,FTL,G3BP2,ARMCX2,NOP53,STAU1,UFL1,ZNF668,BTF3,PDE4B,NOP16,RAB11A,CUL3,MYC,VMP1,NSA2,H1-1,FTSJ3,RPS9,RPL37A,ZNF22,TACO1,APEX1,RPL10,ESR2,RPL7L1,RPF1,ISG15,SOX2,MAK16,MAGEB10,CSNK1E,TOP3B,RAF1,RPL18,CHMP4C,GLE1,EZH2,SREK1IP1,RPS24,RPL31,SSRP1,ZBTB16,H1-6,DDRGK1,RPL6,WWP2,BAZ1B,IFI16,DRG1,RSBN1L,WDR12,DDX23,RPLP2,ZHX1,MYEF2,SRSF1,FBXO32,LYAR,FAM98A,CDK7,TPT1,ZNF770,RPLP0,RPL26L1,RPA2,RAB9A,RNF113A,NLE1,SIRT7,BAP1,INPPL1,BRIX1,UTP23,NHP2,RPL4,FBXW7,KPNA6,RPF2,UBE2H,RC3H2,MECP2,PRKRA,CTTN,METAP2,EIF2AK2,ZNF330,RPS3,PSPC1,DYRK1A,RSL24D1,SRPK2,RPL13A,RPL15,APOBEC3D,AURKAIP1,IMP3,SRP72,NUPR1,ILF2,RBM34,TNFAIP8L1,DHX9,RPL23A,RPL3,NKRF,MDC1,RPL17,IMP4,KPNA2,PAK1IP1,APOBEC3F,COPS5,TMA16,SPATS2L,FOXC2,BRD3,RPL10A,KPNA1,NOL12,MPHOSPH10,SNRNP70,H2AC4,RCHY1,RPL32,SRP14,ZBTB2,SURF6,CD2,RBM42,MBD5,AKAP17A,DKC1,NKAP,CGAS,FZR1,RPS16,CAND1 |
| 1.734e-06 | -13.27 | kidney-carcinoma-renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma | 4535 | 1425 | 16828 | 4835 |
RAB31,ARMCX5,DYRK1A,DRP2,RAB18,FKBP14,IDH2,INSM2,AGER,C1GALT1C1,EIF2AK2,TRIM27,COPS2,AGK,FBXO32,ANAPC2,SHC1,FGFR1,PPP3CA,NME2,CAMK2G,PCK2,SRP54,CIB3,ACO1,SATB1,SCFD1,RABL2B,FAM199X,ARHGEF6,FRMD8,USP2,ZDHHC14,ADRB1,HEY2,ARMCX2,ACTA2,TRIM21,WFDC5,CAMK1,SNX2,PTTG1,PTPN1,TRIM37,HECW1,NFIL3,SEC63,RBBP7,RMND5B,NOVA1,DHRS3,RAB3B,GRAP,JAK1,BAG2,MLF1,ZBTB33,HP1BP3,FBXO42,MCM8,SERPINB10,RIMS3,DLAT,FZD4,JUP,EXT1,VRK1,PGK1,MYH2,DNAJC5,ZMYM2,CFL2,SLMAP,SNX5,MMP9,BUB3,PLP1,RNF41,LMNA,PHF1,KIT,RS1,KPNA1,CSNK2A1,TMEM74,CTNNBIP1,GNG7,CCR6,FOXP3,PPP5C,XAGE5,APOBEC3A,ID4,MAD2L1,CDK5R1,MAP2K6,RASGEF1C,LMO4,CLU,ANAPC11,GNB1,CASK,CDC16,LTBR,ASB8,INPP5E,SOCS4,UBE2A,ARMCX1,CCT2,GHR,CXCL11,UBE2D3,SLC6A8,TRIM23,IRF1,CUL2,PYCARD,PPP1R2,GNAI3,SFN,RAG1,ENY2,RING1,SLC30A5,KLK3,SSR1,SMARCD3,MRPL50,ITK,SWAP70,MYL12A,TRIM46,DNAJC1,CTNNBL1,IDH3B,TIAM1,THAP2,TRIM63,SENP5,JAKMIP1,L1CAM,AKT1,FGD2,IKBKB,TRIM8,DKK3,RAB11A,ASMT,PFDN5,COX10,CDK8,CNP,TFG,RND3,SOCS5,AK2,WDR83,MDM2,MRPL13,ZMPSTE24,FBP2,RSPH1,MAP3K12,ZDHHC15,E2F6,SOX3,RPS4X,ALKBH2,KLK9,DOK4,ARHGAP1,NCKIPSD,RNF141,TRIM32,NFE2,CD99L2,PRIM2,PGM1,IKZF2,LIG3,PRKCQ,TRIM3,KLF10,DIRAS1,ARHGAP21,MCM6,RHCG,ITM2A,ADH1A,BMPR1A,NR0B1,SPOP,CASP4,FBXO9,COX7A1,SASH3,CCND1,IFT57,ACVR1,ANP32B,BCL2L1,DCAF8L2,DMAP1,RAB3C,MTAP,TNFRSF9,DUSP1,BATF,NFYA,PPP1CC,DUSP9,AKR1A1,RBPJ,CXCL9,DEK,PRKD3,RNF152,NUP107,EGLN2,BPGM,CDKN3,SLC35A2,NKRF,MCPH1,ZDHHC8,ID1,POU1F1,CYC1,FBXL3,INPPL1,ASB1,KIF2A,RGS10,SNX3,SIKE1,NCOA5,RUVBL2,IGF2BP1,RAD1,GNAQ,SPRED1,PITPNB,NONO,POLL,ALDH1L1,USP46,SMAD2,SIRT7,ETV6,RABIF,TNFAIP3,KCNH8,RAP2B,DUOXA2,MTMR12,TRAF7,CDC5L,SMURF1,FKBP4,PSKH1,SOCS2,UBE2N,RAB8B,TAF2,CDK6,SGMS2,NCSTN,SLC38A2,P2RY10,USP39,CERK,USP38,CBX7,PROX1,PRKX,FGF13,CX3CL1,LSM6,PEBP1,NAB1,IL5,RAB4A,DHX16,DCLRE1C,LHFPL1,SUMO1,HSPB1,POLD2,KDM2A,TSPAN7,HSPE1,PIK3R1,SERPINH1,EPHA2,NLE1,MAPRE2,XPOT,CXCL1,ITGA2,DIO3,COX6B1,SRSF1,MMP14,RAB6B,RASGRP2,ST13,FBXO30,WWP2,RAP1A,ACAA2,NEDD8,CXCR1,MRAS,MDH1,ELK1,RAB28,KCND2,COPS4,KCNK17,PAOX,GAS8,CDKL2,LMBR1L,NPVF,CBL,APOBEC3C,MED13L,NSDHL,XPO1,EXOC2,IDH3A,RFC5,THRAP3,RNF103,XPO5,POU3F4,UBL4A,HDAC5,FATE1,HECTD3,DNAL4,YES1,VAC14,LDHA,GAPDH,GSK3A,NEK9,TNFSF10,CDK5RAP3,FURIN,FAM3A,UBE2B,CSE1L,FBXO3,AGAP2,PHKG1,PICK1,NTRK3,TSSK1B,NEK7,RNF146,SAP30L,CIRBP,SNIP1,SLC4A8,UBE2D1,RAB1B,RGS5,RBMX2,TNFRSF14,LDHAL6B,RP2,CDKN1A,FOXN2,ORAI3,FBP1,SLITRK2,CLIC2,NLRP1,PPFIA3,CRKL,SOS2,KDSR,DNAJC27,E2F4,PPM1G,MAX,TCEAL7,RHOB,PCGF3,TRIM11,PROM1,TOPBP1,G2E3,GNAI2,DDX4,CAB39,KLK5,CBX5,TOP3B,EZH2,INPP4A,FKBP10,RAB9B,RPS27L,STK11,TESK2,DYRK1B,WIF1,SNX24,TP53INP2,LAMTOR3,STAT6,ARL4A,LITAF,CCNF,WDR44,MEF2C,RAB2A,CTNNA1,FUT1,RPRM,SCYL2,RAB37,PHKA1,FBXO25,DNAJC10,RAF1,STK38,PRRG1,WEE2,PCDH19,RNF14,PNP,RAB5C,DET1,DDX5,EIF4A3,PPP2R1A,SMAD3,RAP2C,TIMP1,UBE2F,FOXP2,IL6ST,CYTH1,CDK5,GNG3,RNF26,RAB13,RNASEL,UTP23,TNFSF18,TOB2,RNF167,RAB33A,OGG1,CCR3,SUMO3,OPHN1,PPFIBP1,SYNGR4,PTGER1,RAB23,WWP1,RHOJ,CBLN4,JUN,PKIG,STAT1,ZNF507,PAX6,FANCG,PPID,RPN1,FOS,DYRK2,OR4N4,EGLN3,DYNLT3,RPL26,TMCC1,RAB14,RIOK2,PC,RAB5A,PRKAG1,HNRNPK,APOBEC3D,NEK2,NFKB1,MAFG,F10,TMEM31,CXCL14,ADAMTS1,RRAS2,BNIP3L,RERG,NUP153,OTUD6A,COPS7A,DDX42,RNF20,PPP1R16A,PGR,EYA3,HSPA14,CXCR4,ANAPC13,GTF2F2,CNTNAP1,PAFAH1B2,HDAC6,RNF39,ASB3,RNF122,ZMYM4,SERPINA5,BTG1,BICD2,GNA14,CXCR6,RAN,USP14,TSC22D3,MMADHC,APLN,TMEM164,YWHAB,PLEKHA8,NUS1,ZCCHC12,RABL3,UPF3B,PPP1CB,NFYB,SESN2,DAPK1,LILRA1,KLHL15,GIT2,NKIRAS1,RUVBL1,ICAM3,RAB3D,LUM,SLC13A5,KDM4B,RGS19,TRIM54,RCE1,RASGRP3,CDC42EP3,MCM3,RAB33B,PDCD4,LDOC1,CREBBP,METTL2A,NLRP6,AKAP14,CHRDL1,FAM162A,CCNB1,PIP5K1A,ERH,UHMK1,PTGER4,TRAF3IP2,GNG2,PIK3R3,MAP3K11,GTF2H2,MORC4,SRC,IDH1,SAT1,GNG13,RASL10A,CCR2,DSTYK,GNG5,HMG20A,IPO8,NDUFA2,GPHN,POLE4,HSP90AB1,FUNDC2,CSRNP1,ATG4A,SYP,PADI2,SFRP4,DNAJC22,PCDH9,ARHGAP25,BCL7B,F9,PGPEP1,CXCL12,SERPINI1,PPM1D,IDO1,APOO,SNX17,TNFSF13,TOP1,EED,ACSL4,TRIM24,CIB2,PPP1R12A,HSCB,TFEB,HSPA8,VMP1,DNTT,OSBP,GOLGA5,SSRP1,TTC32,LMNB1,BECN1,MED21,RAB22A,UBE2V2,AK5,SMC4,FCHSD2,MOSPD1,RNF113A,EFNB1,UBE2M,PIR,TRIM10,TFE3,UBE2E3,CSNK1A1,ITGA6,DDX39A,IGBP1,AKAP12,FOXP4,RNF126,LDHB,COX4I2,CDKN2C,ITGAV,MXI1,USP5,NUP37,TRIM5,EIF4E,FZR1,SMAD4,PPP2R3A,BAK1,ELK4,CD274,FAIM,SMARCA5,DRAM1,PTPN22,SOCS3,FOLR2,NFKBIB,MMP21,RAC2,STK24,PGAM1,LRP6,RNF121,PAX9,ACTB,CNTN1,PRKAB1,GNB4,DERL1,RFC2,SNX18,CSNK1A1L,SOX2,LNX2,SERINC3,KLK6,DNAJC3,STAU1,PLA2G12A,TSN,PFDN4,CDK4,NPR2,RAB30,TRAF2,BRCA1,BCL10,GGT7,NOS1AP,DNAJB2,PDHA1,DUSP19,PPP4C,NME1,RGS2,FCGR2B,SUCLG2,DUSP3,MTM1,BIRC2,SIAH2,POLR1B,KIF3C,CER1,RUNX1,GJC1,SS18,TYMS,UMPS,SCML1,DIRAS2,ARHGAP12,UBP1,IGF1R,CX3CR1,PSEN1,MCM4,MAGEC2,EDA2R,LMO2,FKBP1B,FAM177A1,STARD4,THOC2,ORC6,DROSHA,MGMT,SP1,MDC1,IMPA2,FEN1,FUNDC1,PRKACB,ASB7,TADA3,TRAM1,LANCL2,ERAS,PLEKHO1,MYBL2,CNOT2,SPRY1,ROCK2,KRIT1,ELF5,TRAF6,SCML2,DNAJC19,TKTL1,ADAMTS10,UBE2G2,EP300,FXN,UPRT,RNF8,PEA15,CYTH4,MAP2K1,PLCB2,APOBEC3F,MAGEH1,EIF4A2,OTX2,FEZ1,TRIM26,COPS5,STAT5A,TPM3,SNRPB,RIT1,PTP4A2,FAM3C,PTPN4,WSB1,LYZ,TOPORS,LAMP2,SLC25A5,NLRP9,AR,ADCK1,DMPK,USP3,CDC23,MPG,TGFBR2,TANK,TNFRSF1B,VAMP7,CTTN,RPL23,SPIN3,RABGGTB,NKAP,FBXO7,GNGT2,RRAGB,GABPA,FKBP8,PPP2CB,RASL12,SMAD1,TIMP3,GMPS,PPP3R2,CCR7,TTL,BTG3,GADD45A,GRPR,PPP1R1A,MSTN,RNF148,MX1,PIGA,SAP18,DDR1,SPSB3,HSPD1,EIF1AX,CCNH,POLA2,POLB,PIAS1,PNPLA4,SNRK,WDR45,HSPB6,GNA11,SERPINB1,HSPA5,SRSF2,PIP4K2C,STUB1,PQBP1,GPRASP2,NKIRAS2,ACVR1C,PLS3,TRIM44,TNKS,SLC22A17,STK4,PPP2R2C,ITGB8,BTG2,VAV2,GNB3,HINFP,NCAPG2,ETF1,POLE3,NFKBIA,RNF10,RNF34,MSH6,RAP2A,PPP1R11,KLF4,DENND2D,COPS7B,FBXW4,P2RY4,HLF,SERPINC1,GPM6B,IP6K1,FBXO22,RFC3,RPL10,PTPN11,NOTCH2,FBXL4,FAF1,SRPK2,TAB2,TP53INP1,TRAF3IP3,DTWD1,ASTN1,RPA2,CCR1,CD40,TNFSF15,TLR8,ARFGEF1,TNFSF8,TCEAL1,RGN,FKBPL,RAB6A,USP16,PLAC1,PSMD7,SIN3A,CDK7,DNAJB9,RNF144B,PLCB1,GNAZ,USP15,APOBEC3G,CHRM3,TSR2,SPP1,NTRK2,GNG12,CDK12,FBXW7,EPHA4,PSMD10,TNNI3K,CITED1,ARL4D,CCDC160,CXCL13,RORB,CKS2,MAGEB10,CXCR3,SDHB,PCGF6,RLIM,SURF2,MAGED2,CCNA2,UAP1,YWHAZ,ICAM2,BOK,TNR,NEUROD2,CSNK1G3,RAB39B,PGRMC1,PTK7,FTSJ1,DHX38,COX8A,HUWE1,CPLX2,USP8,UBE2L3,PMAIP1,BCL7C,TCEAL8,TRIM34,PPFIA2,RGL2,ITGB5,FBXW11,NINJ1,ZBED1,DKC1,FBXO44,PNMA3,TRIM29,MCL1,PLD3,NDUFA1,SPRED2,DDX23,PCNA,PIK3R2,NDUFS6,JAK2,NT5DC1,TRIM36,TNKS2,NXT2,HSPB2,STK3,DCAF12L2,PLSCR1,FZD3,PTP4A3,RHOBTB1,DPH3,ELK3,CD81,RHOBTB3,DDX46,OCRL,UBE2E2,RPS6KA4,FBXL14,RHEB,PRKCE,TSPAN17,GRAP2,RAB27A,COX6B2,RNF133,DAAM1,PARP2,NF2,HSPA13,SESTD1,SH2D1A,PPP2R5E,FOXA3,TNF,CCR4,KLF3,SERPINA1,SUMO2,CDC7,ST6GAL1,FBXO8,SGMS1,CBLL1,RBBP8,UBA3,TRIM45,SRSF7,DUSP21,STAT2,SAV1,SNX22,CDC20,GNAO1,XRCC5,TIMP4,IRAK4,NHEJ1,WDR11,TBC1D25,NBN,IL2,RND2,PPP1R1B,BMPR2,BCL9,RASD1,NLRP3,CBX3,HSD17B10,IER2,HERC4,DKK1,USP6NL,SNX10,ZMYM3,OXSR1,ORC5,DLST,BAG3,TMED9,BCL6,RRM1,RBM22,KRAS,CDH11,TMEM185A,APEX2,SF3B1,FBXL19,TMEM47,AP1S2,CHIC2,OR13C8,NUF2,PICALM,COX6C,DAPK3,COCH,RAPGEF5,BAX,CRTC2,RGL1,SUV39H1,IDE,TTC8,TFRC,CKS1B,AUH,RBM41,PABPC5,FOXI3,HMGA1,PRKCB,SKP1,TMBIM6,PCYT1B,GJB1,LCP1,PLCL1,YWHAH,DIRAS3,ADAMTS20,HDAC11,DUSP22,DNAJC7,BCL2A1,ATP6V1D,CDKN2D,HRH2,CDK17,ZNF189,EEF1B2,PTPRZ1,SUPT4H1,VPS39,CLPX,TFDP2,TULP3,BMPR1B,RANBP10,MPP1,FOXC2,RAB32,PITPNA,WNT10B,SPSB1,RBBP9,APOBEC3B,MLH3,FBXO11,PCBP4,NEURL2,CMTM7,SPATA4,SNX12,IRF4,CCND3,ARL6,RAB11B,FGF3,USP13,PLP2,NDP,SMG5,RNF139,NUP62,TNPO2,SRSF4,SH3BGRL,IL7,RAB9A,IFNAR1,SDR16C5,APPBP2,USP30,JUNB,RAD23B,FOXJ3,SMAD9,PTPN5,TCEA1,BCAS4,CHN2,VCPIP1,DDIT3,CACNB2,CYP4F22,CTNND1,KPNA2,SMYD3,DDIT4,STK38L,PIGC,RAB3A,SHC3,CDC26,SPHK2,RCHY1,FGR,ARF6,FBXL7,LBR,MAP2K3,DOK5,STYK1,CXXC1,RGS6,SMARCE1,ZC4H2,CETN2,CBFB,ASPM,PRDX4,SLC25A14,NUP35,MECP2,TFPT,RIT2,ALOX5AP,TNIK,CHST7,SERPIND1,ORAI2,UBE3A,ENO1,MAGEB1,RNF128,DICER1,PTGES,TLR7,SAP30,POU5F1,FGF16,MSN,PPP2R5A,G6PD,ADK,MID1IP1,FTHL17,RALA,SYBU,SERPINB6,ZBTB16,MFAP1,MXD1,HCST,FBXO34,BRMS1L,UBE2I,MAP3K3,RNF7,CCR5,SAR1B,EZH1,CAPG,COX7B,RHOG,FAM83A,ASB11,RGS1,SDHC,KPNA6,TOX,CDH7,KIN,ASCC1,SMUG1,DUSP18,TP53,PPM1B,FBLN5,FOXD3,TRIM35,GPC4,CXCL10,SENP8,DNASE1L1,PML,SERTAD1,ARF4,HMGB1,GNG11,ARF1,PDCD5,DUSP6,CD40LG,PTGER2,MYC,HERC3,RASSF4,SERPINA3,CLK1,TRAF1,BRS3,PPP1R8,ZMAT3,RAB35,TOP2B,BAD,GPR173,PRPS1,GEMIN8,PDCD10,VAPB,PSMA6,AKAP1,CDKN1B,COX7B2,HMGN4,NLGN1,AHSA1,PLEKHF1,DUSP10,CDC42,SYK,ACO2,TRIM62,PSEN2,SNX1,IL2RG,NCK1,STRADB,SIAH1,RHOU,WDR82,DLG3,RPL22,CYTH2,RNF11,RANBP1,ATF3,DNAJC2,GNB1L,ACSS2,MET,FZD6,SNX11,SERPINB9,UBE2V1,S1PR4,HELT,CRADD,PPP1R3C,FKBP2,RALB,GMNN,SNRPA1,ABHD2,TP53I3,DDX1,KDM1A,CCDC22,RNF40,SFRP1,ELF1,LDB1,RANBP6,BIRC5,FGF23,UBE2H,CAMKV,ARL5B,ENO2,PSENEN,PNMA5,GRB10,CSNK1E,CHMP2B,PAK6,DNAJC4,AKT3,BCKDK,POLD4,OR9I1,ARHGAP19,CUL3,ARMCX3,NAP1L3,OR5A2,RBBP4,GPR34,COX6A2,XBP1,MAD2L2,ERCC3,FAS,ATF1,TIMM8A,EGR1,SNX14,AIFM1,RAD21,RAP1B,AKAP17A,DNAJB4,ACVR1B,COX4I1,PIK3CG,LRRC4B,UBE2S,ANAPC4,ARHGAP15,RHOH,GLRA2,RACGAP1,CORO1C,MRPL53,RBM3,HDAC3,MAGEA4,RAB1A,PRKCA,GLO1,PDCD1LG2,AMELX,PIGK,EEF1A1,GAS2,FBXO31,RPL39,TESK1,DVL2,BRD3,AHCYL1,ALDH1A3,HNRNPH2,ANKRD10,CLIC4,SMARCB1,ABCC2,SLC4A10,FOXP1,DCAF16,TRIM6,ENC1,PLCXD3,MMP20,APEX1,GAB1,AKT2,FKBP1A,COTL1,TLR5,RFC4,RNF5 |
| 1.734e-06 | -13.27 | renal_cell_carcinoma | COSMIC cancer mutations | renal_cell_carcinoma | 4535 | 1425 | 16828 | 4835 |
RPS27L,DYRK1B,TESK2,STK11,WIF1,TP53INP2,SNX24,STAT6,LAMTOR3,EZH2,FKBP10,INPP4A,RAB9B,FUT1,RPRM,ARL4A,LITAF,CCNF,WDR44,RAB2A,CTNNA1,MEF2C,DNAJC10,RAF1,STK38,PRRG1,WEE2,RAB5C,PNP,PCDH19,RNF14,DET1,RAB37,SCYL2,PHKA1,FBXO25,TIMP1,UBE2F,FOXP2,IL6ST,CYTH1,EIF4A3,DDX5,PPP2R1A,SMAD3,RAP2C,RBMX2,TNFRSF14,LDHAL6B,SLC4A8,SNIP1,UBE2D1,RGS5,RAB1B,CRKL,SOS2,KDSR,DNAJC27,CDKN1A,RP2,FOXN2,SLITRK2,FBP1,ORAI3,CLIC2,NLRP1,PPFIA3,RHOB,TCEAL7,MAX,PCGF3,TRIM11,PROM1,TOPBP1,G2E3,E2F4,PPM1G,CBX5,TOP3B,GNAI2,DDX4,CAB39,KLK5,NUP153,OTUD6A,COPS7A,RNF20,DDX42,PPP1R16A,ADAMTS1,CXCL14,RRAS2,RERG,BNIP3L,ASB3,RNF122,BTG1,SERPINA5,ZMYM4,BICD2,GNA14,CXCR6,TSC22D3,USP14,RAN,PGR,EYA3,CXCR4,HSPA14,PAFAH1B2,ANAPC13,CNTNAP1,GTF2F2,HDAC6,RNF39,YWHAB,PLEKHA8,NUS1,MMADHC,APLN,TMEM164,SESN2,LILRA1,DAPK1,KLHL15,ZCCHC12,RABL3,UPF3B,NFYB,PPP1CB,TNFSF18,TOB2,RNF167,RAB33A,GNG3,CDK5,RNF26,RAB13,RNASEL,UTP23,WWP1,CBLN4,RHOJ,PKIG,JUN,CCR3,OGG1,SUMO3,OPHN1,PPFIBP1,SYNGR4,PTGER1,RAB23,PPID,RPN1,ZNF507,STAT1,PAX6,FANCG,APOBEC3D,HNRNPK,PRKAG1,RAB5A,PC,NFKB1,NEK2,MAFG,F10,TMEM31,DYRK2,FOS,DYNLT3,OR4N4,EGLN3,RPL26,TMCC1,RIOK2,RAB14,IPO8,HMG20A,CCR2,DSTYK,GNG5,FUNDC2,CSRNP1,PADI2,SYP,ATG4A,SFRP4,NDUFA2,GPHN,POLE4,HSP90AB1,BCL7B,DNAJC22,PCDH9,ARHGAP25,APOO,SNX17,TOP1,TNFSF13,PGPEP1,F9,CXCL12,PPM1D,IDO1,SERPINI1,KDM4B,GIT2,NKIRAS1,RUVBL1,RAB3D,ICAM3,SLC13A5,LUM,CREBBP,LDOC1,PDCD4,RGS19,TRIM54,RCE1,RASGRP3,CDC42EP3,MCM3,RAB33B,PIP5K1A,ERH,UHMK1,PTGER4,TRAF3IP2,METTL2A,NLRP6,AKAP14,CHRDL1,FAM162A,CCNB1,SRC,IDH1,GNG13,SAT1,RASL10A,GNG2,PIK3R3,MAP3K11,GTF2H2,MORC4,NFKBIB,RAC2,MMP21,STK24,RNF121,LRP6,PGAM1,PTPN22,SOCS3,FOLR2,DERL1,RFC2,SNX18,LNX2,SOX2,CSNK1A1L,PAX9,ACTB,CNTN1,GNB4,PRKAB1,STAU1,PLA2G12A,TSN,SERINC3,KLK6,DNAJC3,BCL10,GGT7,NOS1AP,DNAJB2,PDHA1,DUSP19,NME1,PPP4C,RGS2,PFDN4,CDK4,NPR2,RAB30,TRAF2,BRCA1,PPP1R12A,HSCB,TFEB,EED,CIB2,TRIM24,ACSL4,DNTT,GOLGA5,OSBP,BECN1,LMNB1,SSRP1,TTC32,MED21,HSPA8,VMP1,FCHSD2,MOSPD1,EFNB1,RNF113A,PIR,UBE2M,UBE2E3,TRIM10,TFE3,CSNK1A1,ITGA6,RAB22A,AK5,UBE2V2,SMC4,FZR1,SMAD4,PPP2R3A,BAK1,CD274,FAIM,ELK4,SMARCA5,DRAM1,DDX39A,IGBP1,AKAP12,RNF126,FOXP4,LDHB,CDKN2C,ITGAV,COX4I2,MXI1,USP5,TRIM5,EIF4E,NUP37,BAG2,JAK1,MLF1,ZBTB33,DHRS3,GRAP,RAB3B,RIMS3,DLAT,FZD4,HP1BP3,FBXO42,MCM8,SERPINB10,ZMYM2,SLMAP,CFL2,SNX5,MMP9,BUB3,EXT1,VRK1,JUP,PGK1,MYH2,DNAJC5,CSNK2A1,KPNA1,CTNNBIP1,GNG7,TMEM74,PLP1,RNF41,LMNA,PHF1,RS1,KIT,C1GALT1C1,EIF2AK2,TRIM27,COPS2,ANAPC2,FBXO32,AGK,ARMCX5,RAB31,DRP2,DYRK1A,RAB18,IDH2,FKBP14,INSM2,AGER,SRP54,CAMK2G,PCK2,CIB3,ACO1,SATB1,SCFD1,SHC1,FGFR1,PPP3CA,NME2,FRMD8,USP2,ADRB1,ZDHHC14,HEY2,RABL2B,FAM199X,ARHGEF6,PTTG1,PTPN1,HECW1,TRIM37,NFIL3,SEC63,RBBP7,NOVA1,RMND5B,ARMCX2,TRIM21,ACTA2,WFDC5,CAMK1,SNX2,DKK3,TRIM8,RAB11A,ASMT,L1CAM,AKT1,FGD2,IKBKB,SOCS5,AK2,WDR83,MDM2,MRPL13,PFDN5,COX10,CDK8,CNP,RND3,TFG,ALKBH2,KLK9,NCKIPSD,DOK4,ARHGAP1,RNF141,NFE2,TRIM32,PRIM2,CD99L2,FBP2,ZMPSTE24,RSPH1,MAP3K12,ZDHHC15,E2F6,RPS4X,SOX3,TRIM3,PGM1,IKZF2,LIG3,PRKCQ,MAD2L1,MAP2K6,CDK5R1,RASGEF1C,LMO4,CLU,ANAPC11,CCR6,FOXP3,XAGE5,PPP5C,APOBEC3A,ID4,SOCS4,ARMCX1,UBE2A,CXCL11,UBE2D3,GHR,CCT2,SLC6A8,TRIM23,IRF1,CUL2,PYCARD,CASK,GNB1,CDC16,LTBR,ASB8,INPP5E,GNAI3,RAG1,SFN,RING1,ENY2,KLK3,SLC30A5,SMARCD3,SSR1,MRPL50,PPP1R2,CTNNBL1,IDH3B,TIAM1,THAP2,SENP5,TRIM63,JAKMIP1,ITK,SWAP70,MYL12A,TRIM46,DNAJC1,RAD1,GNAQ,SPRED1,PITPNB,NONO,POLL,ALDH1L1,SMAD2,USP46,SNX3,SIKE1,NCOA5,IGF2BP1,RUVBL2,TNFAIP3,KCNH8,RAP2B,MTMR12,DUOXA2,TRAF7,CDC5L,SIRT7,RABIF,ETV6,TAF2,CDK6,NCSTN,SGMS2,SLC38A2,P2RY10,SMURF1,FKBP4,PSKH1,SOCS2,UBE2N,RAB8B,PROX1,FGF13,CX3CL1,PRKX,LSM6,PEBP1,NAB1,IL5,CERK,USP39,USP38,CBX7,NR0B1,SPOP,CASP4,COX7A1,FBXO9,CCND1,SASH3,DIRAS1,KLF10,ARHGAP21,MCM6,RHCG,ITM2A,BMPR1A,ADH1A,DMAP1,MTAP,RAB3C,TNFRSF9,BATF,DUSP1,PPP1CC,NFYA,IFT57,ANP32B,ACVR1,BCL2L1,DCAF8L2,DEK,PRKD3,NUP107,RNF152,EGLN2,CDKN3,BPGM,DUSP9,AKR1A1,RBPJ,CXCL9,FBXL3,INPPL1,ASB1,KIF2A,RGS10,NKRF,MCPH1,SLC35A2,ID1,ZDHHC8,CYC1,POU1F1,MED13L,NSDHL,EXOC2,XPO1,IDH3A,RFC5,THRAP3,RNF103,POU3F4,XPO5,APOBEC3C,YES1,VAC14,LDHA,GAPDH,GSK3A,UBL4A,HDAC5,HECTD3,FATE1,DNAL4,UBE2B,CSE1L,FBXO3,AGAP2,NEK9,FURIN,CDK5RAP3,TNFSF10,FAM3A,SAP30L,RNF146,CIRBP,TSSK1B,PHKG1,NTRK3,PICK1,NEK7,TSPAN7,HSPE1,PIK3R1,SERPINH1,RAB4A,DHX16,DCLRE1C,LHFPL1,SUMO1,HSPB1,POLD2,KDM2A,XPOT,CXCL1,ITGA2,COX6B1,DIO3,SRSF1,EPHA2,NLE1,MAPRE2,NEDD8,CXCR1,MRAS,MDH1,ELK1,RAB28,KCND2,MMP14,RAB6B,RASGRP2,ST13,FBXO30,WWP2,RAP1A,ACAA2,PAOX,CDKL2,GAS8,NPVF,LMBR1L,CBL,KCNK17,COPS4,FGF3,USP13,PLP2,SMG5,NUP62,NDP,RNF139,NEURL2,CMTM7,SPATA4,SNX12,IRF4,CCND3,ARL6,RAB11B,SDR16C5,IFNAR1,APPBP2,SH3BGRL,SRSF4,TNPO2,IL7,RAB9A,BCAS4,TCEA1,CHN2,VCPIP1,USP30,RAD23B,JUNB,FOXJ3,SMAD9,PTPN5,CTNND1,CYP4F22,KPNA2,STK38L,SMYD3,DDIT4,RAB3A,PIGC,SHC3,CDC26,DDIT3,CACNB2,RBM41,PABPC5,FOXI3,HMGA1,PRKCB,SUV39H1,RGL1,IDE,TFRC,TTC8,CKS1B,AUH,PLCL1,YWHAH,DIRAS3,ADAMTS20,DUSP22,HDAC11,DNAJC7,TMBIM6,SKP1,PCYT1B,GJB1,LCP1,EEF1B2,PTPRZ1,ZNF189,SUPT4H1,VPS39,CLPX,TFDP2,BCL2A1,ATP6V1D,CDKN2D,HRH2,CDK17,FOXC2,PITPNA,RAB32,WNT10B,SPSB1,APOBEC3B,RBBP9,MLH3,FBXO11,PCBP4,TULP3,BMPR1B,RANBP10,MPP1,KPNA6,TOX,COX7B,RHOG,FAM83A,ASB11,SDHC,RGS1,PPM1B,TRIM35,FBLN5,FOXD3,GPC4,CXCL10,SENP8,ASCC1,KIN,CDH7,SMUG1,DUSP18,TP53,SERTAD1,ARF4,DNASE1L1,PML,PDCD5,DUSP6,HMGB1,GNG11,ARF1,MAP2K3,DOK5,STYK1,CXXC1,SPHK2,RCHY1,FGR,ARF6,LBR,FBXL7,TNIK,ORAI2,SERPIND1,CHST7,UBE3A,ENO1,SMARCE1,RGS6,CETN2,ZC4H2,ASPM,CBFB,PRDX4,SLC25A14,MECP2,NUP35,TFPT,RIT2,ALOX5AP,MID1IP1,ADK,G6PD,FTHL17,RALA,SERPINB6,SYBU,MAGEB1,DICER1,RNF128,PTGES,SAP30,TLR7,FGF16,MSN,POU5F1,PPP2R5A,MAP3K3,SAR1B,CCR5,RNF7,CAPG,EZH1,ZBTB16,MFAP1,MXD1,FBXO34,HCST,BRMS1L,UBE2I,RANBP1,ATF3,GNB1L,DNAJC2,ACSS2,RHOU,WDR82,DLG3,RPL22,RNF11,CYTH2,SNX11,UBE2V1,S1PR4,SERPINB9,HELT,CRADD,PPP1R3C,FZD6,MET,SNRPA1,ABHD2,TP53I3,KDM1A,DDX1,CCDC22,RNF40,FKBP2,RALB,GMNN,UBE2H,ARL5B,CAMKV,ENO2,PSENEN,PNMA5,ELF1,SFRP1,LDB1,RANBP6,FGF23,BIRC5,RASSF4,SERPINA3,CLK1,TRAF1,PPP1R8,BRS3,ZMAT3,RAB35,CD40LG,PTGER2,MYC,HERC3,PDCD10,VAPB,TOP2B,BAD,PRPS1,GPR173,GEMIN8,CDKN1B,COX7B2,NLGN1,HMGN4,PSMA6,AKAP1,PSEN2,SNX1,IL2RG,NCK1,STRADB,SIAH1,PLEKHF1,AHSA1,DUSP10,CDC42,SYK,ACO2,TRIM62,RPL39,TESK1,DVL2,BRD3,RAB1A,GLO1,PRKCA,PDCD1LG2,AMELX,EEF1A1,PIGK,GAS2,FBXO31,HNRNPH2,ANKRD10,CLIC4,ALDH1A3,AHCYL1,SLC4A10,FOXP1,DCAF16,TRIM6,ENC1,PLCXD3,MMP20,SMARCB1,ABCC2,RNF5,APEX1,AKT2,GAB1,FKBP1A,COTL1,RFC4,TLR5,DNAJC4,POLD4,BCKDK,AKT3,OR9I1,GRB10,CSNK1E,CHMP2B,PAK6,RBBP4,GPR34,COX6A2,XBP1,MAD2L2,ERCC3,ATF1,FAS,ARHGAP19,CUL3,ARMCX3,NAP1L3,OR5A2,ACVR1B,TIMM8A,EGR1,SNX14,AIFM1,RAD21,AKAP17A,RAP1B,DNAJB4,RACGAP1,CORO1C,GLRA2,RBM3,HDAC3,MRPL53,MAGEA4,COX4I1,PIK3CG,LRRC4B,UBE2S,RHOH,ARHGAP15,ANAPC4,CYTH4,APOBEC3F,MAP2K1,PLCB2,FEZ1,EIF4A2,MAGEH1,OTX2,COPS5,TRIM26,STAT5A,ADAMTS10,UBE2G2,EP300,UPRT,FXN,RNF8,PEA15,TOPORS,LYZ,WSB1,LAMP2,NLRP9,SLC25A5,AR,ADCK1,SNRPB,TPM3,RIT1,PTPN4,FAM3C,PTP4A2,VAMP7,CTTN,RPL23,SPIN3,RABGGTB,FBXO7,NKAP,GNGT2,DMPK,USP3,CDC23,MPG,TGFBR2,TANK,TNFRSF1B,TIMP3,GMPS,PPP3R2,TTL,CCR7,RRAGB,PPP2CB,FKBP8,GABPA,RASL12,SMAD1,RUNX1,GJC1,SS18,TYMS,UMPS,SCML1,FCGR2B,SUCLG2,DUSP3,MTM1,BIRC2,SIAH2,CER1,KIF3C,POLR1B,MCM4,MAGEC2,PSEN1,EDA2R,FAM177A1,LMO2,FKBP1B,STARD4,THOC2,ORC6,DROSHA,DIRAS2,ARHGAP12,UBP1,IGF1R,CX3CR1,IMPA2,FEN1,FUNDC1,PRKACB,ASB7,TADA3,TRAM1,LANCL2,MGMT,SP1,MDC1,ROCK2,KRIT1,TRAF6,ELF5,SCML2,DNAJC19,TKTL1,ERAS,MYBL2,PLEKHO1,CNOT2,SPRY1,RNF34,RAP2A,MSH6,PPP1R11,COPS7B,DENND2D,KLF4,ETF1,NCAPG2,POLE3,NFKBIA,RNF10,RPL10,FBXW4,HLF,SERPINC1,P2RY4,IP6K1,GPM6B,FBXO22,RFC3,FAF1,SRPK2,TAB2,TP53INP1,TRAF3IP3,DTWD1,RPA2,ASTN1,CCR1,PTPN11,NOTCH2,FBXL4,TNFSF8,RGN,USP16,FKBPL,RAB6A,TCEAL1,PSMD7,PLAC1,CDK7,SIN3A,CD40,TNFSF15,TLR8,ARFGEF1,PPP1R1A,MSTN,RNF148,MX1,PIGA,BTG3,GADD45A,GRPR,HSPD1,CCNH,EIF1AX,POLA2,POLB,PNPLA4,PIAS1,SAP18,DDR1,SPSB3,STUB1,PIP4K2C,GPRASP2,PQBP1,ACVR1C,NKIRAS2,WDR45,SNRK,HSPB6,GNA11,SRSF2,HSPA5,SERPINB1,ITGB8,BTG2,VAV2,GNB3,HINFP,PLS3,TRIM44,TNKS,SLC22A17,STK4,PPP2R2C,UBE2L3,PMAIP1,CSNK1G3,RAB39B,NEUROD2,PGRMC1,FTSJ1,PTK7,DHX38,HUWE1,COX8A,USP8,CPLX2,TRIM34,PPFIA2,RGL2,ITGB5,FBXW11,NINJ1,BCL7C,TCEAL8,MCL1,NDUFA1,PLD3,DKC1,ZBED1,FBXO44,PNMA3,TRIM29,TNKS2,HSPB2,NXT2,STK3,DCAF12L2,PTP4A3,RHOBTB1,FZD3,PLSCR1,SPRED2,PCNA,DDX23,PIK3R2,NDUFS6,JAK2,TRIM36,NT5DC1,USP15,CHRM3,APOBEC3G,TSR2,NTRK2,SPP1,GNG12,RNF144B,DNAJB9,PLCB1,GNAZ,EPHA4,PSMD10,TNNI3K,CITED1,ARL4D,CDK12,FBXW7,MAGEB10,CXCR3,PCGF6,SDHB,CCDC160,CXCL13,RORB,CKS2,YWHAZ,ICAM2,BOK,TNR,RLIM,SURF2,MAGED2,CCNA2,UAP1,IER2,HSD17B10,RND2,PPP1R1B,BCL9,BMPR2,RASD1,CBX3,NLRP3,OXSR1,DLST,ORC5,TMED9,BAG3,BCL6,KRAS,RRM1,RBM22,DKK1,HERC4,USP6NL,SNX10,ZMYM3,SF3B1,APEX2,TMEM47,FBXL19,AP1S2,CHIC2,CDH11,TMEM185A,BAX,CRTC2,NUF2,OR13C8,COX6C,PICALM,DAPK3,RAPGEF5,COCH,FBXL14,RHEB,PRKCE,TSPAN17,RAB27A,GRAP2,RNF133,COX6B2,CD81,ELK3,DPH3,RHOBTB3,DDX46,OCRL,UBE2E2,RPS6KA4,TNF,CCR4,KLF3,SERPINA1,SUMO2,DAAM1,NF2,PARP2,HSPA13,SESTD1,FOXA3,PPP2R5E,SH2D1A,SGMS1,RBBP8,CBLL1,UBA3,SRSF7,TRIM45,STAT2,SAV1,DUSP21,CDC7,ST6GAL1,FBXO8,IRAK4,WDR11,NHEJ1,TBC1D25,NBN,IL2,SNX22,CDC20,GNAO1,TIMP4,XRCC5 |
| 1.736e-06 | -13.26 | PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1) | protein interactions | 5351 | 286 | 117 | 19454 | 5460 |
VDAC2,LMBR1L,CYB5R3,CDC7,MIRLET7B,SEC61B,FBXO22,MIRLET7D,AUH,MYC,CUL3,CUL2,MIR98,PDE4B,TOMM40,MIR363,DNAJC3,TMEM106B,HSPA8,BIRC2,EP300,AKAP1,EMC1,STAU1,PYGB,TOMM22,DUSP14,CNDP2,DNM2,MIR7-2,PHB1,MIR141,MIR214,HNRNPL,KIF3B,C1QTNF1,MIR9-1,CACYBP,LRWD1,PDIA3,WWP2,MIR143,HNRNPA1,RHOG,CBL,DDX1,MIR221,HSPD1,HNRNPA2B1,PABPC1,MIR9-2,MIR206,VDAC1,RAF1,B3GNT2,E2F4,TXNRD1,DNAJC25,MIR222,ISG15,EZH2,RND3,RPGRIP1L,PTPN11,RC3H2,DNAJC10,STK11,UBE2H,RBM7,CALU,RPA3,NCDN,MIR10B,SIRT7,HNRNPH2,LSM12,MIRLET7I,HMCES,RNF113A,GPX4,GTF2I,MIR7-3,HSPA5,MIR34B,MIR1-2,RPA2,SEPHS2,SSBP1,COQ8A,EFNA3,DLGAP4,CDCA3,CAND1,DCUN1D1,MIRLET7G,GNPTG,DPP4,CALR,COPS5,POR,SNRNP70,DNAJC7,MIR34A,NOSIP,MAP1B,NAE1,IGF1R,EMC2,DNAJC30,MIRLET7C,RIGI,H2AX,MIR15A,MIR17,HSPA13,MIR20A,NUPR1 |
| 1.741e-06 | -13.26 | SPATS2 (spermatogenesis associated serine rich 2) | protein interactions | 65244 | 104 | 52 | 19454 | 5460 |
RPS10,HNRNPL,FAM98A,KCTD10,WIF1,SURF6,KRR1,IFI16,WWP2,XPO1,DDRGK1,ERLEC1,RIGI,RUSF1,MRFAP1L1,LTBR,RPL3,RTCB,PSMC3,MOB3C,RAF1,E2F4,SOX2,ISG15,DAPK1,SPCS1,ESR2,RPL10,TRIM44,TNFRSF1B,LURAP1,FGFBP1,PRKRA,PHAX,AP2M1,RMDN3,RPS20,DCAF4,HSP90AA1,H1-1,MYC,RPL7A,ZNF668,ANAPC15,STAU1,TRIM10,EXOSC4,RNF113A,RPL26L1,NUP62,EHHADH,BORCS6 |
| 1.756e-06 | -13.25 | HINT1 (histidine triad nucleotide binding protein 1) | protein interactions | 3094 | 166 | 75 | 19454 | 5460 |
DDAH2,CLIC4,SH3BGRL,TRIM29,TXNDC12,TAGLN2,PRDX2,TXN,RMDN3,ENO1,ENO2,CCNF,FXN,UBE2H,FKBP1B,CA2,PFDN2,SP1,RGN,MTPN,CDC16,MYC,RGS19,GPC1,SRI,OXCT1,SNX24,PMP2,UCHL3,GPX4,PRDX6,PTRHD1,RPA3,SOD1,BAP1,GSTO2,FKBP1A,SCLT1,RPA2,SNRNP27,JMJD8,SPR,FABP7,ACTL6A,CDK9,PRNP,LYRM2,MITF,MIF,MTAP,GATD3,AKR1B1,SIN3A,FABP5,NME2,CTNNB1,LYPLAL1,PPIB,SAR1B,MPST,GSTT1,FKBP2,HSPE1,GNL1,RUVBL1,GUK1,TAGLN3,HINT1,RUVBL2,EWSR1,EZH2,VPS33A,UBE2V1,HINT3,GLRX5 |
| 1.776e-06 | -13.24 | regulation of inflammatory response | biological process | GO:0050727 | 428 | 171 | 18204 | 5365 |
CCR2,VAMP3,NINJ1,MIR657,MIR222,NLRP3,TLR2,SPATA2,MIR16-1,MIR141,NFKB1,CASP4,NLRP2,NPY5R,RB1,ALOX5AP,IL2RA,VAMP2,PDE2A,MIR105-1,TMSB4X,FCGR2B,S100A8,DUSP10,PSMA1,STAP1,PYCARD,MIR361,AGER,NLRP1,FEM1A,SYK,MIR205,OTULIN,BCL6,MIR145,MIR920,PIK3AP1,RHBDD3,CCN3,BIRC2,YES1,VAMP7,TNF,ADIPOQ,CAMK2N1,IL10,XCL1,SMAD3,CX3CL1,PPARG,AREL1,UFL1,PTGER4,SETD4,CCL1,OSM,TNFAIP8L2,MIRLET7G,SEMA7A,IL23A,MIR195,DROSHA,IL15,MIR181C,MIR590,KLF4,TLR4,PIK3CG,CD200,IL18,PSMB4,SRC,ADORA1,IL21,TNFAIP6,TRIM45,PDCD4,MIR15A,IL13,CD47,CTSC,IFNG,IDO1,IL2,MIR221,IFI35,CNR1,SOD1,MIR20A,GHRL,IL22,NDFIP1,MIR206,LACC1,LTA,FCGR1A,MIR488,DEFB114,NLRP6,MCPH1,JAK2,TLR7,CD200R1,MIR187,ACP5,CCR7,SELENOS,IL1B,DHX9,VAMP8,HYAL2,GSTP1,TNFAIP3,GPX1,CCL24,NFKBIA,IGF1,KARS1,MIR144,MIR149,CD81,FABP4,MIR146A,NLRP9,MIR21,LPCAT3,SOCS5,IL20RB,TNFRSF1B,TLR9,MIR31,ABHD12,IL4,MYD88,MGST2,CD28,CMA1,BAP1,CASP12,SOCS3,NMI,FURIN,MIR204,IRF3,IL6ST,PPARA,CCL3,PSMA6,FOXP3,LDLR,DDT,HTR2A,MIR126,IL6,IER3,MIR142,PTGES,NUPR1,GPR17,PYDC2,MMP9,MIR223,GPSM3,CCL5,FOXP1,MACIR,IL12B,FGR,TLR3,DUOXA2 |
| 1.784e-06 | -13.24 | NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7) | protein interactions | 374291 | 292 | 119 | 19454 | 5460 |
POR,CHCHD1,TMEM70,NR2F6,GPRASP2,GRSF1,EMC4,NDUFA1,SSBP1,COX4I1,GFM2,NDUFS3,APOO,AURKAIP1,BCS1L,METTL15,ATP5PB,MRPL11,MTCH2,NDUFA2,FASTKD5,DNAJC30,CHDH,EMC2,NRP1,DNAJC19,UBE2H,TUFM,HMOX2,NDUFB10,UQCRQ,MGST3,UQCRC2,CINP,CCNF,CYC1,MTRES1,COX6C,RPA2,MMADHC,HSP90B1,UQCRC1,CRAT,MPV17,TIMMDC1,CRYZ,KDM1A,PDHB,SLC25A51,GFM1,NDUFC2,RPA3,MRPS26,POU5F1,NDUFB8,NQO1,RHOG,AGR2,NDUFV2,DDRGK1,MTRF1,EGLN3,UQCRH,NDUFS8,RMND1,COX14,HNRNPL,CORO1C,GATD3,ATP6V1A,HDHD5,PHB1,NDUFA12,NUDT19,EZH2,PDHA1,NDUFS6,EEF2,E2F4,IMMP2L,EMC8,HINT2,PREPL,HSPD1,NDUFB5,BCKDK,NDUFA4,TOMM40,PCCB,AUH,MTG2,NDUFB7,NDUFB6,CUL3,PMPCA,IREB2,NDUFAF4,PARL,ESR2,ATP5F1B,PHF21A,LMBR1L,VDAC2,TACO1,ENO2,CCDC90B,FAM3C,NDUFA5,PDP2,ARMCX3,NDUFAF3,TOMM22,FTL,HSCB,NDUFS2,PHB2,HADHA,NGRN,EXD2 |
| 1.789e-06 | -13.23 | process utilizing autophagic mechanism | biological process | GO:0061919 | 316 | 132 | 18204 | 5365 |
VPS33A,RB1CC1,SRC,CHMP1B,MAP1LC3B,HSPA8,DRAM1,PHB2,HSP90AA1,SNAP29,WDR45,GPR137,TFEB,SQSTM1,EVA1A,RNF41,RAB23,RGS19,MAP1S,TP53,TBC1D25,TP53INP1,LAMP2,VPS4A,TOM1,CHMP1A,ATG101,USP30,KLHL3,DNM2,GABARAPL2,ATG7,SMURF1,LIX1,STX12,CHMP5,TMEM208,UFL1,IFI16,RETREG1,STX17,CHMP4C,FUNDC2,ATG9A,PSEN1,MTM1,RAB39B,CHMP2A,FBXO7,MCOLN1,GABARAPL1,VPS18,PIM2,OPTN,SNAPIN,TRAPPC4,RAB1A,TAX1BP1,CHMP2B,EI24,TP53INP2,VTI1B,USP13,HMGB1,CLU,PTPN22,STUB1,VPS28,VAMP8,RAB1B,EMC6,TMBIM6,NSFL1C,VPS4B,GABARAP,HDAC6,S100A8,VPS39,C9orf72,FUNDC1,STK11,UBXN6,TRIM5,ATG4A,DDRGK1,LGALS8,STBD1,ATG16L1,CTSK,VMP1,RAB2A,RAB33A,VAMP7,ANXA7,FBXL4,TEX264,SNX14,RAB33B,XBP1,VTA1,NRBF2,TBC1D17,TOLLIP,TRAF6,VPS16,BAG3,TBC1D5,RETREG2,BECN1,RIMOC1,TM9SF1,PLAA,TMEM74,FIS1,UFM1,CTSD,RAB19,TMEM59,ATG4C,TSG101,PHF23,RETREG3,SH3GLB1,TMEM39A,ATG3,HGS,MAP1LC3A,IRF8,TAFAZZIN,UBXN2B,DAP,VIPAS39 |
| 1.789e-06 | -13.23 | autophagy | biological process | GO:0006914 | 316 | 132 | 18204 | 5365 |
HSP90AA1,SNAP29,PHB2,SQSTM1,RNF41,EVA1A,GPR137,WDR45,TFEB,VPS33A,RB1CC1,HSPA8,MAP1LC3B,DRAM1,SRC,CHMP1B,LAMP2,TP53INP1,CHMP1A,TOM1,USP30,ATG101,VPS4A,RGS19,RAB23,MAP1S,TBC1D25,TP53,STX17,RETREG1,CHMP4C,IFI16,UFL1,ATG9A,RAB39B,MTM1,PSEN1,FUNDC2,SMURF1,GABARAPL2,KLHL3,DNM2,ATG7,TMEM208,CHMP5,STX12,LIX1,TAX1BP1,RAB1A,CHMP2B,EI24,GABARAPL1,VPS18,TRAPPC4,SNAPIN,OPTN,PIM2,VTI1B,TP53INP2,FBXO7,MCOLN1,CHMP2A,HDAC6,S100A8,VPS4B,GABARAP,UBXN6,TRIM5,FUNDC1,C9orf72,VPS39,STK11,STUB1,PTPN22,HMGB1,USP13,CLU,NSFL1C,TMBIM6,VPS28,EMC6,RAB1B,VAMP8,CTSK,VMP1,RAB2A,SNX14,RAB33B,VAMP7,ANXA7,RAB33A,TEX264,FBXL4,STBD1,ATG16L1,DDRGK1,LGALS8,ATG4A,PLAA,FIS1,TMEM74,RETREG2,TM9SF1,RIMOC1,BECN1,TMEM59,ATG4C,UFM1,RAB19,CTSD,TBC1D17,NRBF2,TOLLIP,XBP1,VTA1,TBC1D5,VPS16,TRAF6,BAG3,IRF8,HGS,MAP1LC3A,TAFAZZIN,VIPAS39,DAP,UBXN2B,TSG101,PHF23,ATG3,RETREG3,SH3GLB1,TMEM39A |
| 1.796e-06 | -13.23 | mitochondrial membrane organization | biological process | GO:0007006 | 115 | 58 | 18204 | 5365 |
MTCH2,GHITM,SLC25A31,TOMM70,TMEM14A,HSP90AA1,TIMM10,SLC25A46,GCLC,TOMM22,CHCHD6,ACAA2,TIMM13,CNP,TOMM40,SLC25A4,BAX,IER3,BAK1,BCS1L,BOK,TP53,MUL1,NAIF1,CIBAR1,ROMO1,UQCC3,VDAC2,BLOC1S2,PPIF,SLC35F6,CHCHD3,ATP5IF1,TRMT10B,TOMM7,APOO,TIMM8A,MTX2,AGK,MIR17,BNIP3L,PPM1K,MIR29A,BAD,TIMM8B,SLC25A5,PMAIP1,TAFAZZIN,TOMM6,GSK3A,TIMM29,MAIP1,BCL2L1,CLN8,TOMM20,MIR29C,SAMM50,TMEM11 |
| 1.800e-06 | -13.23 | ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5) | protein interactions | 10550 | 180 | 80 | 19454 | 5460 |
YWHAB,UPK1A,ESYT1,H2BC17,FAM241B,FAM241A,YWHAG,YWHAH,LAMP3,ICAM2,ADIPOR2,RAB5C,NUP35,TMEM170A,SLC25A12,RHOH,DERL2,ARF6,DNAJC1,RAC2,CLN8,HSD17B11,PTPN1,ACTR2,RPN1,DMAP1,PPP2R1A,DNAJC25,LPAR6,TP53,CCDC47,UBL4A,MAX,TSPAN11,NOC4L,HNRNPK,KRAS,LPAR2,PLSCR1,CCR5,YWHAZ,LMNB1,RHOB,ATP1B3,PRRT1,CIAO1,ESR2,VIRMA,SLC25A4,COPE,CCR2,SLC1A1,SEC61B,GPR173,RETREG3,MOG,CYB5R3,S1PR4,SCLT1,SIGMAR1,SSR1,P2RY12,RPA2,LMNA,ST7,CDC42,SEC62,OTULINL,RND2,ARL6,LPAR1,ARPC2,RTN4,DERL1,TMEM185A,VIPR1,TACR1,SYVN1,TSPAN15,RPA3 |
| 1.806e-06 | -13.22 | RRP12 (ribosomal RNA processing 12 homolog) | protein interactions | 23223 | 295 | 120 | 19454 | 5460 |
COX8A,RPS24,FGF3,RPL31,KRAS,H1-6,CHCHD2,LGR4,SOX2,B3GNT2,TOP3B,SART3,RPS11,HDAC11,CHMP4C,EED,NUP35,RPL7,RPS10,POLR3F,NOP58,DDRGK1,ATG7,RPL6,WWP2,IFI16,LHX2,POU5F1,DDX23,HSPA8,COIL,NOP53,UFL1,RND2,BET1,SYK,H1-5,PIH1D1,RPS9,SEC61B,PRMT5,AP2M1,LMBR1L,APEX1,RPL19,MAD2L2,RPL10,FBXO22,RPL35,ZNF668,RAB11A,CUL3,SCN3B,MYC,H1-1,DNAJB6,ATG3,H1-10,RHOB,PSKH1,RPL23A,ABCE1,RPL3,SNIP1,RIGI,RPL17,RPS13,H3C1,RPL15,AURKAIP1,RPSA,SRP72,HBP1,PRR3,KRR1,SRP14,ZBTB2,SURF6,CAV1,RPS16,CAND1,CSNK2A1,COPS5,HDAC6,GRSF1,RPS2,SNRNP70,H2AC4,CHCHD1,RAB9A,RNF113A,PML,SIRT7,BAP1,RPA3,BRIX1,AATF,FBXW7,RPL4,EIF5B,RBMS2,ATG16L1,RPS14,WDR5B,KLF4,GRM2,RPA2,LMNA,TMEM74,FGFBP1,TNFRSF1B,ZNF330,RPS3,CCNF,SRPK2,VIRMA,DNAJC8,UBE2H,ATP1A1,RC3H2 |
| 1.830e-06 | -13.21 | UBE2V1 (ubiquitin conjugating enzyme E2 V1) | protein interactions | 7335 | 112 | 55 | 19454 | 5460 |
XBP1,HBB,RPA2,SOD1,RPA3,UGDH,RNF10,TRIM5,BIRC2,UBE2K,YKT6,RNF5,UCHL3,ATP6V1G1,RNF11,SFN,LDHB,TRIM32,TRAF3IP2,RC3H2,YWHAZ,PSMD14,CHORDC1,PELI3,POMP,RIT1,STUB1,TAGLN2,TXN,ESR2,UBE2V2,SMURF1,TRAF2,SOX2,UBE2B,ZNRF1,ZYX,HSD17B10,FAM168A,HINT1,KRAS,PELI1,AHCYL1,UBE2A,TRIM8,GMPPB,RNF14,YWHAG,TRAF6,AGR2,NME2,UBE2N,PSMB1,TTC9C,G6PD |
| 1.837e-06 | -13.21 | MAF (MAF bZIP transcription factor) | protein interactions | 4094 | 59 | 34 | 19454 | 5460 |
PSMD12,PSMC1,PSMA1,HUWE1,PSMA5,EP300,PSMA3,FOS,PML,PSMC3,HOXD12,PSMB7,NFE2L2,JUN,SOX9,MAFG,PSMC4,USP5,PSMD4,HNRNPL,PSMD6,PSMC5,UBE2I,SIN3A,PSMA6,HERC4,PSMD14,PSMD7,PSMD1,PSMD3,SMARCA5,CREBBP,ATF4,PSMA4 |
| 1.857e-06 | -13.20 | SF3B5 (splicing factor 3b subunit 5) | protein interactions | 83443 | 128 | 61 | 19454 | 5460 |
HSPD1,SNIP1,RIGI,SNRPG,MEPCE,VRK1,KRAS,RPSA,RAF1,RHOBTB1,SNRPE,PPP4C,SMNDC1,DDX42,SRSF1,CWC15,DHX15,MIRLET7G,SNRPA1,SNRPD3,OCRL,API5,RBM17,WWP2,TAF9,STAMBPL1,RPS2,SNRNP70,SKIC8,SF3B1,RPA3,SNRPA,DDX46,FBXW7,SGF29,UFL1,SUPT3H,SNRPN,SF3A1,ATG16L1,CSNK1A1,TRAPPC6A,SUPT7L,MIR21,TOX4,SF3B4,SNRPD2,SNRPD1,SF3B6,SNRPB2,COPE,PPP1CC,DNAJC8,TTC33,SNRPB,MYC,TAF5L,UBE2H,RIT1,TADA1,TADA3 |
| 1.868e-06 | -13.19 | TGFBR2 (transforming growth factor beta receptor 2) | protein interactions | 7048 | 197 | 86 | 19454 | 5460 |
PSMA3,TERT,SQSTM1,PGK1,PML,ARHGEF6,FADS2,LRP10,HTR1A,BMPR1A,CLU,TGFB1I1,PSMC1,PIK3R2,USP8,SLC7A1,RAB6A,TRAM1,CDC42,ARHGAP1,COQ8B,PSMC4,OXSR1,IDH2,MAP2K1,FGFR1,PLAA,CDK1,RCE1,TSSK1B,VIRMA,SEC63,SLC25A31,ABHD12,SMURF1,UMPS,NDFIP1,YES1,STAT1,UFD1,CCNB1,PIK3R3,PSMA4,HSP90AA1,SMAD2,NRP1,PSMD14,JAK1,FAF1,DDR1,SPSB1,EHD4,CALHM2,TGFBR2,ACVR1B,TRMO,RCVRN,YTHDF2,CCDC47,RAB6B,ACVR1,ATP6V1A,PPP2CB,KRR1,RPL8,SMAD3,ACSL4,WDR6,WDR44,CDC5L,CAV1,PEG10,SPTAN1,ATXN10,ADCK1,CTNNB1,USP2,PIK3R1,SLC20A1,CBL,TGFB2,FBXO34,TGFB3,PEX3,TRAF6,SMAD4 |
| 1.873e-06 | -13.19 | EPB41L2 (erythrocyte membrane protein band 4.1 like 2) | protein interactions | 2037 | 263 | 109 | 19454 | 5460 |
ABCE1,KLHL15,SNIP1,PPP1R12A,MEPCE,CAMKV,TOLLIP,DRD1,TP53,ADORA1,CCT5,TAF2,NUPR1,DDX42,TFCP2,HRAS,SYNCRIP,STX6,ZBTB2,CAV1,ARF6,GRM1,PRNP,NKAP,HDAC6,COPS5,CSNK2A1,H2AC4,SNRNP70,RPA3,BAP1,PML,SIRT7,HSPA5,CERS2,DDAH1,ARHGAP1,ARL15,RPA2,TOX4,DRD3,CCNF,CTNNA1,CTTN,PPP1R10,SRPK2,DDAH2,ATP5F1A,DNAJC5,USP14,PPP1CC,RAB2A,SMARCA5,MLF1,PTPN11,NCKIPSD,PPIG,MECP2,FAM76B,UBE3A,FKBP2,PAX6,FLOT1,COPS4,KRAS,RAF1,ZRANB2,MOB3C,TUBB4B,GJA1,BRD9,COPS2,RAB35,WDR6,SRSF10,DIRAS3,HSP90AB1,NUP35,COPS7B,SPTAN1,YWHAH,YWHAG,HSPB1,YWHAB,FKBP4,PMAIP1,STX7,KRT222,SEC62,WDR77,CLDN4,NUFIP2,MFAP1,CNDP2,GRIA1,ATXN1L,POLR2B,ESR2,APEX1,TAX1BP1,DYNLL1,SNRNP40,RBM15B,COPS7A,MYC,SFN,LAMTOR1,RHOB,YWHAZ |
| 1.899e-06 | -13.17 | NME1 (NME/NM23 nucleoside diphosphate kinase 1) | protein interactions | 4830 | 183 | 81 | 19454 | 5460 |
SORD,UBE2H,YWHAZ,CHRAC1,BRCA1,NIF3L1,CCT2,GORASP2,USP14,CFL1,NTAQ1,CUL3,MYC,CTSD,APEX1,TNPO3,VIRMA,RORB,DYNLL1,TUBB,PTEN,MSN,S100A6,PIH1D1,WTAP,RARS1,PPT1,JUP,VAPB,CFTR,DUSP22,SMYD3,HSPA5,CCND3,RANBP10,OXCT1,EYA3,NME4,FXR2,PRDX6,AKAP1,HDAC5,HSPA8,GID8,BAP1,SOD1,NQO1,HSPB1,AGR2,TIAM1,TUBG1,NME2,PID1,MARCHF5,CRIP1,PRDX1,CCT7,HSP90AB1,TCP1,MIF,KCTD15,NME1,CHMP4C,TNPO2,EEF2,CCT5,FBP1,RAF1,DUSP19,FOXP4,TRIM37,RUVBL1,RBBP7,SREK1IP1,EMC2,IDH1,ZC3H7A,CCT8,HNRNPA2B1,MAP1B,HSPD1 |
| 1.904e-06 | -13.17 | SKI (SKI proto-oncogene) | protein interactions | 6497 | 158 | 72 | 19454 | 5460 |
RIGI,RPS4X,TRIM37,PCNA,MKLN1,MAEA,PABPC1,SLC25A5,AKT2,LTBR,HSPD1,RPL18,SCHIP1,SMAD1,TUBA1A,JUN,SERPINA3,TP53,HSP90AB1,TCP1,HNRNPL,RPS16,RB1,RPL12,SIN3A,SMAD3,ARMC8,RB1CC1,PPM1B,SMAD4,SIAH2,SAV1,DYRK1B,PRDX1,HSPA5,PYGB,GRPEL1,STK38,RPL4,EYA3,HDAC3,DDX5,SQSTM1,HADHA,HSPA8,GID8,PML,RPLP0,ATP5PO,KLF3,WDR77,SMAD5,VIRMA,SLC25A4,ACTB,TUBB,ATP5F1B,LDHA,UBE2I,PRMT5,TUBA1B,UQCRC2,RPS3,ATP1A1,SMAD2,MECP2,AR,TUFM,ATP5F1A,STK38L,ZMYND19,AKT1 |
| 1.904e-06 | -13.17 | APOE (apolipoprotein E) | protein interactions | 348 | 158 | 72 | 19454 | 5460 |
TUFM,HMOX2,ST13,ATP5F1A,RHEB,AKT1,RPS26,HSP90AA1,PDCD4,YWHAZ,ALB,CYB5R3,MID1IP1,UQCRC2,FBXO22,ACTB,MANSC1,PRDX2,CTSB,ATP5F1B,ANKH,TIMM29,PRDX3,UQCRC1,RPS14,CYC1,APOC2,ATP5PO,CYP2C18,HADHA,HSPA8,VLDLR,RPS28,HSPA5,RPL4,PHB2,NPTN,PDHB,CTNNB1,TPM3,IQSEC1,CSNK2A1,CD81,RPL6,MICB,NDUFB8,POR,ATP6V1A,LDLR,PHB1,RPL8,NDUFS8,UQCRH,PRNP,HTRA1,EEF2,RPS7,TMEM59,CYB5R1,ARFGAP1,SLC25A24,NDUFS3,PDHA1,CYP2C8,TFRC,EMC2,SFXN1,S100B,PSEN1,FARSA,VDAC1,EMC8 |
| 1.905e-06 | -13.17 | GRB2 (growth factor receptor bound protein 2) | protein interactions | 2885 | 769 | 274 | 19454 | 5460 |
TOM1L1,PPP5C,NCKAP1,FBXO22,SF3B4,SMU1,CD3G,POMP,CCT2,PNRC1,ATG3,PSMD14,CUTA,BAG3,LMO2,COPS7A,MYC,EPS8,HNRNPC,EEF1G,PHB2,ADRB2,HSPA8,SPATA2L,EP300,MIA2,PIH1D1,CKS2,FRS3,PAK2,IL6ST,CD59,SYK,USP6NL,ELK1,HSP90AB1,CCT7,TCP1,S100A8,SH2D1A,FABP5,CBL,HSPB1,YWHAB,DRG1,NCK1,FKBP4,AGR2,YWHAH,SHC3,YWHAG,WWP2,FKBP2,TFG,KRAS,EPHA4,RUVBL1,ADRB1,RUVBL2,DNAJB4,PIK3CG,UQCC2,CCT8,GHR,BTG1,SLC1A2,CRKL,SH2D5,HGS,TUBB4B,EEF2,ERRFI1,FASLG,MYG1,SRC,IGF2BP1,UBE2H,SNTA1,NIF3L1,H2BC9,GSTK1,PTPN11,HSPA5,BCL2A1,CLU,PARD6A,DRD3,PTPN22,FGFR1,CD2AP,POLR1D,CDC42,DDIT4L,SPTBN1,LCP2,EPHB6,ESD,CD28,MYL12A,SLAIN2,FZR1,CEBPG,HCLS1,ITK,ITGA6,SYNCRIP,CD247,SHC1,FCGR2B,CCL5,HP,FCGR2A,COPS5,CD81,GAPDH,DNAJB2,H2BC14,CAPZA1,STRADB,AKAP12,H3C1,PSMA5,KPNA2,CSE1L,HNRNPK,SOS2,PIK3AP1,MAP1B,PSME1,GRAP2,SPRY1,PIK3CA,IK,NFE2L2,AGER,TMSB10,WBP11,H2AX,ARHGAP12,SELL,PRRC2A,USP5,JAK2,TUBB,DYNLL1,ACTB,TAB1,SNRPD2,AP2M1,FAU,RNF208,NTRK3,HSP90AA1,RIT1,ELMO2,YWHAZ,PIK3R3,CUL3,CSRP1,FTL,DNAJC22,CYFIP2,RNF10,HEXB,SLC25A3,VAV2,OTULINL,WDR77,ACTL6A,PRKAB1,LNX2,PPIA,EGLN3,WDR44,OCRL,COPS7B,SNX18,TSG101,KRT8,COPS2,DNM2,WDR6,PHB1,HNRNPD,CDKN1B,NQO1,PPP3CA,LAT2,PIK3R1,CLPX,BABAM1,RPS27A,COPS4,KIT,BPGM,JAK1,HSPD1,SLC25A5,HNRNPA2B1,AP2S1,KIAA0408,TULP3,PNMA5,TRIM27,PTEN,ODR4,RPS20,UBASH3B,GAB1,STUB1,ENO1,CTTN,CHRM4,AP2A1,EPHA2,NCKIPSD,XPOT,CASC3,SLX1A,SYP,ATP5F1A,RACGAP1,PPP1CC,SKAP2,AR,CSK,CD164,IL2RB,SS18,VPS28,SIT1,B2M,PIK3R2,USP8,H2BC12,PPIH,INPPL1,RHOU,DVL2,RARS1,MET,STAMBP,KRT7,ZMYM6,METTL14,FTH1,ATG16L1,UBA52,MYL12B,NFYB,G6PD,DCUN1D1,PRNP,SOCS4,TCEAL8,RB1,PTPN1,ETV6,HRAS,NAP1L5,DNAJC4,STYK1,CRBN,GRAP,DAG1,WASL,TF,NTRK2,IGF1R,MAP1LC3B,PPARA,MAP2K3,MTA3,CCT5 |
| 1.909e-06 | -13.17 | POMK (protein O-mannose kinase) | protein interactions | 84197 | 266 | 110 | 19454 | 5460 |
VIRMA,TECR,SEC61A1,B4GALT1,SCAMP2,GXYLT1,CDIPT,CD1E,GGCX,LRP6,XPOT,ATP1A1,SDF2L1,TMEM106C,ATP5MC1,CLU,LPAR1,SMC4,CERS2,RPS15,RTN4,VIPR1,MME,CYB5D2,APMAP,CHPF2,TM9SF1,CCL18,GOLGA5,GHITM,TRAM1,TMEM106A,SLC35E1,ILVBL,ATP5PD,STT3A,ACSL4,SRPRA,FITM2,AGPAT1,PSMD7,TUBG1,TMBIM6,KLHL22,ATP5MG,BMPR1B,EI24,LPCAT3,RDH11,PSEN1,CSE1L,SRPRB,YIF1A,TMX3,SLC16A1,SLC25A11,ATP5PF,SLC25A10,TMEM165,SURF4,ATP5PB,ALG5,B4GAT1,ABHD12,REEP4,B4GALT3,SEC61B,RETREG3,GGT7,PIGK,LMBR1L,CD79B,SLC38A1,PSMD14,GGH,KDSR,CERS6,PSMC1,RER1,HSCB,SLC35F2,HADHA,ATP5F1E,FDFT1,ARCN1,ELOVL1,SIGMAR1,ATP5PO,TSHR,SLC19A2,PGRMC1,TLCD4,DNAJB9,XPO1,PTDSS1,SEC61A2,TMED7,ATP5F1D,PGAP4,USP30,SLC39A7,PLD3,CYB5B,AQP3,RPN1,TMEM59L,DIPK1A,TMEM59,DCAKD,B3GNT2 |
| 1.918e-06 | -13.16 | positive regulation of leukocyte activation | biological process | GO:0002696 | 362 | 148 | 18204 | 5365 |
IL1B,CD40,AKT1,BCL6,PPP3CA,HMGB1,CD1D,SYK,CD226,DUSP10,STAP1,PYCARD,AGER,CCR7,TLR6,STAT6,KARS1,XCL1,IL10,SLC39A10,IL1A,VSIR,TNF,CD209,ACTB,EP300,IGF1,CD2,RPS3,NCK1,SELENOK,TFRC,TOX,YES1,IL2RG,SHLD1,MIR145,KMT5B,TESPA1,GPAM,FGF10,NLRP3,TRAF6,CCL21,XBP1,TNFSF13,CD38,RHOH,PDCD1LG2,CYRIB,IL2,CCR2,TGFBR2,EFNB1,MIR130A,AIF1,CCL19,DPP4,TIRAP,CDKN1A,SPHK2,CCL2,JAK2,TNFRSF14,IL2RA,ICOS,IL5,BAD,RAG1,IL15RA,LILRB1,DHPS,IL12A,FOXP3,SRC,CD274,HSPD1,BCL10,CD83,CCL3,IL18,PNP,MIF,SASH3,ACTL6A,NKAP,CD40LG,LEP,TLR4,KLHL25,THY1,SMARCE1,PELI1,NECTIN2,PTPN11,IL6ST,BTN2A2,CTSC,IFNG,SLC7A1,MMP14,IL12B,CCL5,CD47,PIK3CA,ACTL6B,MIR142,IL13,CD86,CSK,CLEC7A,IL21,IL6,IL4,MYD88,TACR1,ZBTB16,PRKCQ,SOCS5,RUNX1,SMARCD3,TLR9,LILRB4,CD81,PLPP6,MIR30B,MIR21,CD4,CD46,SMARCB1,WNT10B,HMCES,CAV1,IL15,TYROBP,EPO,TICAM1,MAD2L2,CHRNB2,EXOSC3,MEF2C,IL7,CD28,B2M,CD80,CBFB,BLOC1S3,IL23A |
| 1.926e-06 | -13.16 | IKBKB (inhibitor of nuclear factor kappa B kinase subunit beta) | protein interactions | 3551 | 217 | 93 | 19454 | 5460 |
LRRC14,EEF1AKMT3,BCL10,DPP4,NFKB1,GTF2E1,COPS5,TOLLIP,KPNA2,SMN1,FAF1,TFRC,ACVR1,TAB2,RNF8,TBK1,TP53,DUSP1,MAP3K3,PRKCE,UBB,ROCK1,TRAF1,SRC,OPTN,EIF2AK2,CSNK2B,TRIM27,RETSAT,AKT1,TNFAIP3,BRAP,TRAF3IP2,RPL4,BNIP3L,PRKCB,MTDH,MAVS,SQSTM1,PRKCA,CXCL8,CCAR2,PRKCQ,EGLN3,HSP90AB1,MACROD1,TNIK,HOMER3,IKBKB,PPM1B,FKBP4,TRAF6,HSPB1,YWHAB,GSTM3,RPL6,CTNNB1,MAP3K14,SPATA2,PELI1,TNF,COPS4,MRFAP1L1,MAP3K11,TRIM21,NLRP2,E2F4,TRAF2,JUN,TAX1BP1,TAB1,USP5,NFKBIA,NFKBIB,RAN,LAMTOR1,BRCA1,FBXW11,HSP90AA1,POLR1B,COPS7A,CREBBP,MYC,CUL3,PYCARD,RNF11,SKP1,CD40,PEBP1,STK26,PPARG,TANK,PRDX3 |
| 1.947e-06 | -13.15 | regulation of protein phosphorylation | biological process | GO:0001932 | 917 | 334 | 18204 | 5365 |
FCGR1A,DEFB114,DIRAS3,CDK5RAP3,DVL2,GSK3A,HGS,PRKCE,MAP2K1,PKIB,FGF1,RIT2,LRP6,MACROH2A1,NRP1,IL5,TSG101,MMD,TLR7,JAK2,PTEN,CARTPT,DIRAS2,SOD1,SLC8A1,CRKL,DLG3,CDK12,CCND1,CTDSP1,IL2,TGFBR2,MIR221,PAK2,FAS,CBL,PID1,KIT,STAT2,SOX9,TADA3,RGN,ODAM,MIR20A,CCNI,SPRED2,MT3,NCK1,CCND3,SLC1A1,GH1,FGF10,GSTP1,HYAL2,BAK1,TXN,CHP1,TGFB2,MAP2K3,DUSP3,PIK3R3,OSBP,DBNDD1,KRAS,IGF1,SPRED1,PDCD10,PROX1,TNFSF18,C9orf72,ADTRP,GREM1,ADRB2,IFNA13,SLCO3A1,CCR7,TLR6,NOP53,DKK1,TNFSF15,AKT1,IL1B,RAP2B,PTPN22,CAV3,PRKAG1,EFNA5,ZNF592,UCN,CDKN2D,CD36,AGAP2,HSP90AB1,CD80,CLEC6A,MAVS,TAB1,SMYD3,MAD2L2,CAV1,IFNB1,SOCS3,PAX6,TNIK,HBEGF,CD4,MIR30B,MIR21,IFNA2,DNAJC3,LILRB4,PSEN1,MIR146A,CDKN3,LCP2,SFN,EHD4,IGFBP3,SMG8,CREBL2,IL4,RGCC,NPTN,MOB3C,PKIG,IFNK,TLR9,SOCS5,EMP2,CNKSR3,HDAC3,IFNA10,GNAQ,PPIA,MMP9,CD86,DUSP19,HSPB1,FERMT2,BAX,ERP29,TOM1L1,SFRP1,RTRAF,IL6,MOB3B,FGR,UBE2K,TLR3,EPHA4,IL12B,MIR106B,YWHAG,CCL5,FLOT1,CTDSP2,CDK5R1,VEGFC,PARD6A,PRNP,IL6ST,SOCS4,HAX1,CSF2,SPRY1,HSP90AA1,MAP3K12,CLIP3,IL12A,MIR132,HTR2A,INPP5K,TPD52L1,ROPN1B,ERRFI1,PSRC1,MIF,STRADB,ADNP,RB1,ILK,TESK1,DRD1,PIH1D1,ARL2BP,CDKN1A,TNFRSF14,NHERF1,MAP2K6,PSMD10,CHI3L1,DUSP6,HCLS1,XRCC5,TRIB1,TBK1,CLDN3,F2,DIRAS1,CCL19,GADD45A,TRAF6,CCNF,RARRES2,CAMK2N2,ACVR1,CCNH,GSKIP,SERTAD1,RPS3,TRIM6,LACRT,YES1,TFRC,DUSP1,PHB1,CDKN2C,CX3CR1,RAP1A,TRAF2,RAF1,MIR24-1,CX3CL1,ROCK2,DUSP22,MAP3K11,DDRGK1,CAMK2N1,ACTB,FGF3,FGF17,TNF,ADIPOQ,HRAS,PYCARD,PKIA,AGER,STK11,STK38,DUSP10,NKX3-1,FBXW7,BCCIP,HDAC6,CAB39,PRR5L,RALB,RGS2,CD40,HEXIM2,FGF7,FGF16,SYK,CORO1C,DNAJC10,CEP85,NF2,IL7,EZH2,IL3,UBASH3B,CHRNA7,IL23A,VEGFA,SEMA7A,IL34,FGF23,CNOT7,IL15,MIR137,EPO,CCNB1,CCNA2,CAMK1,PAQR3,NBN,TLR8,NTRK3,MIR218-1,MIR212,NTRK2,PPARG,SESN2,GPNMB,MIR711,OSM,FAXDC2,RAP2A,IMPACT,CDKN1B,MIR34A,LEPR,CAMP,MIR15A,IL13,CACUL1,PDCD4,IL21,STK4,FKBP8,IFNG,NTF4,TCIM,TP53,TAB2,CCNY,DIPK2A,TAF7,PIK3CA,THY1,PIK3CG,TRIM27,SQSTM1,LEP,DLG4,APLNR,TLR4,ZBED3,PHB2,HEXIM1,PTPN11,SRC,GHR,PTPN1,FGF22,ANGPT1,RAP2C,P2RY1,FGFR1,MIR26B,PTPRQ,RB1CC1,IL18,CSH1 |
| 1.951e-06 | -13.15 | TRMT10C (tRNA methyltransferase 10C, mitochondrial RNase P subunit) | protein interactions | 54931 | 200 | 87 | 19454 | 5460 |
MTRF1,H2AC14,DPP4,GRSF1,EMC4,ASB1,DDRGK1,RHOG,SNRNP70,CHCHD1,TMEM70,MRPS26,POU5F1,AIFM1,SSBP1,GATD3,RAC2,COPS2,FZR1,CAND1,RHOH,EGLN3,CDC5L,FBP1,RAF1,MRPL11,TP53,WBP11,MIR15A,AURKAIP1,MAP1LC3B,METTL15,PDHA1,GFM2,MAP1B,HSPD1,TCOF1,HECTD3,HINT2,HSD17B10,COX8A,G3BP1,CHCHD2,THRAP3,FASTKD5,MEPCE,MTG2,AUH,MYC,CUL3,PMPCA,TUFM,USP14,RHOB,UBE2H,DNAJC19,TACO1,CCNF,MTG1,CCDC90B,MACROH2A1,CAVIN2,RHOJ,PARL,SRPK2,ESR2,BET1,CDC42,RND2,USP39,RPA2,FGFR1,UBE2M,HEXIM1,MTRES1,RHOU,NGRN,PPM1G,EXD2,HSPA8,GFM1,HADHA,AKAP1,UFL1,HSCB,FBXW7,DUSP26 |
| 1.973e-06 | -13.14 | SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2) | protein interactions | 6601 | 325 | 130 | 19454 | 5460 |
RAB1B,SPTAN1,SNRPA1,SIN3A,EED,BRD9,AGR2,POU5F1,HNRNPD,LHX2,IFI16,BAZ1B,PIK3R1,WWP2,BCL7C,ACTL6B,RBBP7,RUVBL1,ASF1A,GTF3C3,PAX6,BCL7B,TOP2B,EWSR1,UBE3A,EZH2,STMN2,MTA2,SMARCB1,POLR2C,RBPJ,RAF1,E2F4,SOX2,JUN,NUP153,NCSTN,SAP30,STAT2,RBBP4,SNRNP40,ACTB,APEX1,ATXN1L,RAN,PRMT5,MCPH1,GTF2F1,LMNB1,BRCA1,SP1,CREBBP,MYC,CUL3,HNRNPC,SMARCE1,DRAP1,CPSF2,SAP18,SMARCD3,HIRA,FOS,EP300,NUP50,DDIT3,PSMA3,ADNP,IFTAP,ACTL6A,KLF1,TOP1,CDC5L,SMAD3,H2AZ1,SMAD4,NOVA1,SNRNP70,BRD3,USP15,MOV10,GTF2E1,CSNK2A1,H3C1,KPNA2,MEPCE,MDC1,MSH6,SNIP1,PPP1R12A,CDK8,TOPORS,ING1,MAP1LC3B,ACTR1A,H2AX,SOX9,TMOD3,VIRMA,NMI,DEK,CCNF,ZNF330,UBN1,ING2,PSMC5,RAB3C,MACROH2A1,SMAD2,UBE2H,AKT1,SMARCA5,H2BC9,RUNX1,AR,KDM1A,FBXW7,MBD3,SS18,RPA3,SIRT7,BANF1,PHYHIP,RPA2,GRM2,HSP90B1,HEXIM1,SF3A1,ATG16L1,CCNH,CFTR |
| 1.977e-06 | -13.13 | ARF1 (ADP ribosylation factor 1) | protein interactions | 375 | 272 | 112 | 19454 | 5460 |
UBE2H,AP3S2,CDC73,ARFGAP3,AGAP2,TUFM,PRKACB,ARHGAP21,RAB2A,VIRMA,COPE,LDHA,RALA,B4GALT1,CYTH1,AGAP1,UBE2M,SSR1,GOLGA5,LDHAL6B,RPA2,TMEM106A,PIP5K1A,RPL4,ARFIP1,RAB9A,TMEM263,RPA3,TRAPPC2L,LAMP3,TMPO,POLE3,PRNP,ARF6,CAND1,RPS16,HSD17B11,PTPN1,TRAPPC13,GLRX5,WBP11,CHRM3,CYTH2,ARF4,RAB3B,HUWE1,IGF1R,HAPSTR1,RPL3,RAB1A,SLC38A1,NOA1,RHOB,LAMTOR1,SLC30A5,GALE,RAB11A,OPRM1,LDHB,B4GALT3,SEC61B,ARF1,ARCN1,USP39,RAB6A,DUSP22,SEC62,GOSR2,STX7,STAU1,EEF1G,PPP2R3A,AKAP1,RAB5A,PEX3,CBL,AHSA1,AGR2,CTNNB1,WWP2,RAB5C,LAMP2,RAB11B,HSP90AB1,DIRAS3,RPL7,RAB1B,GJA1,RAB35,RPL9,RPL18,RPS11,RAB4A,RAB6B,CHMP4C,KDELR1,RPN1,EZH2,STIM1,PLEKHA8,B3GNT2,HTR2A,RAF1,ARFGAP1,ETFA,VDAC1,KRAS,ZC3H7A,SLC39A3,SLC39A7,PICK1,TMT1A |
| 1.988e-06 | -13.13 | RAB11FIP5 (RAB11 family interacting protein 5) | protein interactions | 26056 | 172 | 77 | 19454 | 5460 |
TULP3,GLRX5,PPP2R1A,RAB4A,HINT1,KLHL15,NTRK2,HAPSTR1,TRIM21,RAB3B,KRAS,MPST,FLOT1,ZCCHC10,LAMP2,YWHAG,XPO1,LAMP3,YWHAH,ESYT1,RHOG,YWHAB,STYK1,BRD3,ANXA4,RAB35,SMAD3,RAC2,GATD3,SELENOM,GJA1,ARF6,INA,CAV1,RAB11B,STX6,EGLN3,RBM42,JMJD8,SUMO1,ATG16L1,MRPL12,GABARAPL2,CDC42,FGFR1,PML,DVL2,RHOU,RAB9A,RAB5A,PGK1,SRI,NAPG,SGF29,STX7,RAB11A,MYC,ISCA2,DNAJC5,MTPN,JPT1,YWHAZ,RHOB,LAMTOR1,FXN,NCKIPSD,NTRK3,ENO1,SCAMP2,RHOJ,TXNDC12,RAB14,CTSB,ERH,VIRMA,DDAH2,CBX5 |
| 1.997e-06 | -13.12 | GNAI2 (G protein subunit alpha i2) | protein interactions | 2771 | 243 | 102 | 19454 | 5460 |
EZH2,NGB,GNG3,SOX2,RAF1,TOP3B,MED9,TOMM6,KRAS,GPSM3,PLSCR1,RINT1,BCKDK,CBL,MDFI,MRGPRX1,STK3,HSP90AB1,ADCK1,CORO1C,GNB3,DUSP6,SRSF1,LMBRD2,TSHR,RND2,DUSP22,TOMM22,RGS19,GNB4,ADRB2,NMRAL1,HSPA8,TTC1,PMAIP1,DUSP9,BMPR1A,DDX39B,HSP90AA1,RHOB,LMNB1,BTF3,MYC,OPRM1,GNB1,APEX1,ESR2,EDNRA,RGS5,CYB5R3,VAC14,GNAI3,NUPR1,FURIN,TFCP2,CAPZA2,MAP1LC3B,GNG10,ADORA1,MTCH2,RIGI,CNR1,TOLLIP,GNG5,IGF1R,CCR5,CXCR1,CD81,HDAC6,GNG2,CYSTM1,SLC25A17,CAV1,CD4,P2RY12,PAK5,GNG7,RPA2,METTL14,CXCL8,KDELR2,CFTR,ADIPOR1,HSPA5,RASD1,CRYL1,SQSTM1,RHOU,LHB,RPA3,NRP1,MAPRE1,CHRM1,TNFAIP3,RAB2A,VIRMA,RHOJ,GNAO1,PCP2,PTEN,OPTN,CCNF |
| 1.997e-06 | -13.12 | TPM1 (tropomyosin 1) | protein interactions | 7168 | 243 | 102 | 19454 | 5460 |
TWNK,MYH2,BAP1,FBXW7,HMGB1,CDK7,CFTR,CDC42,SPTBN1,WTAP,TMOD1,SCLT1,HSP90B1,PSMC5,EIF4A3,RPS3,STUB1,CCNF,DYRK1A,HOMER1,AR,NDUFB10,AKT3,SORD,CCHCR1,RAB27A,TFPT,MDC1,PSMB10,TOLLIP,H3C1,TSSC4,TP53,ATP5PB,RNF181,FURIN,RNF8,CAPZA2,TNNI1,TFCP2,SEC23A,TES,PSMB1,RAP1B,ACTA2,COX4I1,CDK9,TMPO,THOC1,KCTD15,TPM3,HDAC6,COX5A,KXD1,TMOD2,DNAJC7,EP300,SF3B1,FOS,TNNT2,STAU1,UFL1,MYH1,PPP1CB,DLST,SRXN1,APEX1,ESR2,ACTB,STAT1,BTF3,MYC,VMP1,SP1,BRCA1,CKB,MT3,ZYX,AHCYL1,TRIM37,ETFA,VDAC1,TNF,PSMA1,G3BP1,TRIM26,ISG15,ACTN4,SNAPIN,JUN,TOP3B,RAF1,RBPJ,RND3,CHMP4C,IRF8,EZH2,THOC2,FHIP1B,CTNNB1,YWHAG,HSPB8 |
| 1.999e-06 | -13.12 | DEPDC1B (DEP domain containing 1B) | protein interactions | 55789 | 186 | 82 | 19454 | 5460 |
UHMK1,ANAPC4,CA2,LAMTOR1,YWHAZ,RHOB,DNAJC5,SMARCA5,CDC16,RAB2A,RAB11A,FAM110B,PYCR1,CHCHD3,RHOJ,AGAP1,ZNF326,LARP4B,CDC42,SIPA1L1,RND2,ATG16L1,STX7,SMC4,FAM53C,RAB9A,AKAP1,RAB5A,RHOU,RTKN,CDC23,STYK1,RHOG,SNRNP70,XPO1,YWHAG,LAMP3,YWHAH,PSMD3,DDX50,LAMP2,RAB5C,ERLIN1,DKC1,DIRAS3,LMAN1,CETN2,CAV1,ARF6,KCTD3,CAND1,DYNC1I2,RHOH,HSD17B11,GJA1,RAC2,HP1BP3,RAB35,RPRD1A,HRAS,COQ8A,EIF4E2,RND3,BIRC5,RHOBTB1,NEFL,RAB4A,NUP153,LBR,SRSF12,MCM6,MDC1,HUWE1,KRAS,RUVBL1,CSE1L,RAB3B,BSCL2,MRPS18B,COX8A,TESK2,SFXN1 |
| 1.999e-06 | -13.12 | CLNS1A (chloride nucleotide-sensitive channel 1A) | protein interactions | 1207 | 186 | 82 | 19454 | 5460 |
CSNK2A1,PGAM1,MAGOH,DDX1,LSM3,PDCD10,RPS2,CRBN,DCK,ALYREF,SYNCRIP,WDR6,MIF,SNRPD3,NOB1,FAM98A,FZR1,SPPL3,RPL15,UBL4A,SNRPE,PIR,PLS3,LSM10,PDIA6,EIF1AD,SMN1,SNRPG,RIGI,MEPCE,VRK1,NEDD8,LSM4,KRAS,PSMA5,G3BP1,SNRPB,CUL3,RIT1,UBE2H,PFDN2,RC3H2,LSM6,FAS,CIRBP,SNX12,WDR45,PRMT5,RTRAF,SNRPD2,SNRPD1,EIF4A3,S100A6,FAU,VIRMA,USP5,DDAH2,SMURF1,ACTB,LGALS3,EIF4A2,ELK4,CDK7,UBA52,SNRPN,WDR77,RBFOX2,ALKBH3,AGAP1,UBE2M,GRM2,LSM2,PTP4A2,EP300,RNF113A,RAB5A,HNRNPH2,NMRAL1,BAP1,HSPA5,UFL1,WDR3 |
| 2.024e-06 | -13.11 | negative regulation of vascular endothelial cell proliferation | biological process | GO:1905563 | 25 | 19 | 18204 | 5365 |
MIR133B,MIR495,CCL2,MIR193A,MIR29C,MIR24-1,MIR132,MIR30E,MIR98,MIR152,MIR126,PPARG,MIR129-1,MIR503,MEF2C,MIR34A,MIR30B,MIR424,MIR492 |
| 2.025e-06 | -13.11 | Simplified Depiction of MYD88 Distinct Input-Output Pathway | WikiPathways | WP3877 | 19 | 17 | 5310 | 1910 |
TLR7,UBE2N,TLR10,TLR2,TRAF6,TLR4,NFKB1,MYD88,IL1A,JUN,TLR1,TLR5,TIFA,TLR6,UBE2V1,TLR9,TLR8 |
| 2.038e-06 | -13.10 | aerobic respiration | biological process | GO:0009060 | 149 | 71 | 18204 | 5365 |
FXN,UQCRQ,SDHB,ATP5PO,MDH1,COX4I1,SLC25A51,NDUFA2,COX6C,NDUFB8,COX7A1,SLC25A14,PDHA1,SDHC,NDUFS6,COX7B2,ATP5PF,NDP,OGDHL,NDUFC2,ATP5F1D,UCN,NDUFB5,TAFAZZIN,COX8A,NDUFA4,IDH3B,ATP5F1E,NDUFS3,IREB2,IDH1,COX6B2,NDUFB4,UQCRC2,CYC1,COX5A,KGD4,PDHB,ACO1,NDUFA12,NDUFA5,ACO2,NDUFB7,IDH2,SDHAF2,NDUFA1,NDUFS8,NDUFAB1,ATP5F1A,NDUFB10,UQCR11,DLAT,NDUFB6,COX10,NDUFV2,ATP5F1B,DLST,COX6B1,UQCRC1,ATP5PD,COX7B,STOML2,ATP5PB,UQCC3,COX6A2,SUCLG2,NDUFS2,IDH3A,UQCRH,COX4I2,ATP5MG |
| 2.039e-06 | -13.10 | DNAJA3 (DnaJ heat shock protein family (Hsp40) member A3) | protein interactions | 9093 | 349 | 138 | 19454 | 5460 |
APOBEC3B,MTG2,MYC,PRMT6,CUL3,NTRK3,HSP90AA1,SCFD1,ILK,GCC1,BRCA1,MRPL13,MCPH1,PHF12,NFKBIB,DLST,NFKBIA,NDUFAF4,JAK2,MAD2L2,MRPL23,TIMM21,TUBB,MRPL12,NDUFAF3,TMEM231,TCF19,NDUFA5,ATP5PO,PPARG,HSPA8,THBS3,RPS28,COIL,MRPS7,UFL1,NDUFS2,PHB2,HNRNPA1,NDUFV2,DDRGK1,MAP3K14,CLPX,STOML2,MRPS35,MRPS26,SMAD9,POU5F1,HAX1,FOSL2,RHOG,PHB1,EGLN3,NDUFS8,RAB1B,PCSK9,TUBA1A,TULP3,B3GNT2,E2F4,ETFB,NDUFA12,SMARCB1,STK16,PLD3,RPS23,PDHA1,HDAC11,CHMP4C,NDUFS6,COX8A,HSPD1,ARGLU1,KRAS,ETFA,MTPN,FBXO7,RUNX1,USP14,NDUFAF2,NDUFB10,PYCR2,UBE2H,ATOSB,RC3H2,PTPMT1,PTEN,MRPL53,STUB1,CCNF,UQCRQ,VIRMA,TXN,EIF4H,ATG16L1,MET,MRPS34,GHITM,FGFR1,GRM2,RNF34,RNF113A,BAP1,GRPEL1,POLDIP2,KDM1A,CIDEB,GRSF1,DPP4,COX5A,SSX2IP,SNRNP70,SDHB,SSBP1,MRPS9,COX4I1,ATP5PD,MRPS23,FZR1,MRPL50,CTDSP2,AURKAIP1,CHRM3,NDUFA2,TP53,FURIN,MRPL49,TFRC,NDUFS3,MRPS18B,IGF1R,RAB1A,FASTKD5,MRPL22,RIGI,FKBP8,HUWE1,NOC4L |
| 2.039e-06 | -13.10 | FNDC3B (fibronectin type III domain containing 3B) | protein interactions | 64778 | 161 | 73 | 19454 | 5460 |
TPM3,KARS1,HSPB1,RPL23,HNRNPD,NCK1,TIAM1,EIF5A2,SPINT2,DSTN,RPL12,SYNCRIP,NUP35,ABHD8,SPMIP5,SNRPD3,TRIM35,RAB1B,RPL15,TRAF2,STPG4,VAC14,DISC1,PC,HSPD1,RAB1A,RPL17,RIGI,RPL28,HNRNPK,G3BP1,ATP5F1A,SPMIP10,CFL1,MCCD1,ZMYND19,MYC,CSK,ATP1A1,YWHAZ,GTF2F1,SLCO1B3,ALB,SLC1A1,HAPLN2,ENO1,RAN,RPS3,PRRC2A,ESR2,DUSP10,VIRMA,ERH,TXN,CDC42,NDUFAB1,UBA52,EEF1E1,RBFOX2,RPS14,SRARP,MYL6,WWP1,TOX4,SPCS2,OR1M1,PSMA3,HSPA8,PGK1,SOD1,ACTMAP,HSPA5,STAU1 |
| 2.041e-06 | -13.10 | nucleobase-containing compound biosynthetic process | biological process | GO:0034654 | 896 | 327 | 18204 | 5365 |
ATP5F1B,VDR,SNAPC1,NPR2,PCNA,CTNNB1,TWNK,RPRD1B,ATP5PD,TCEANC2,PRPS1,NUDT2,ENY2,UQCC3,DPY30,POLB,RFC3,DR1,EP300,DKC1,SKIC8,ATP5MG,GTF2H5,SIRT7,KARS1,GTF2B,FUBP3,MTERF2,PRMT5,PDHB,UAP1,ADRB2,ZNF345,SMAD4,PRDM4,PROX1,CHRAC1,NFKBIB,NDUFA1,CEBPE,NPM3,QNG1,DHX9,ADCY2,POLR1D,ATP5MC1,KPNA6,RPRD1A,ACACA,DCK,JAK2,PPP5C,TAF11,SMAD1,MED31,NHP2,MACROH2A1,DNPH1,NR1H2,CYTL1,IL2,POLA2,TOPORS,HIRA,CDK12,SNAPC5,NDUFA2,TRIM24,AR,CDK7,RRN3,TERC,SUB1,XBP1,SOX9,SART3,ATP5PF,MTF1,TECR,POLL,GTF2F1,CREB1,RCHY1,NDUFB6,SLC25A1,PADI2,MARS1,NKX3-2,DNAJC30,ACSL4,STOML2,POLD4,DNTT,WWP2,MMUT,HACD2,POLR3B,POLR2C,USP15,MED21,BARX2,NDUFB7,HSP90AA1,NFIL3,GNPNAT1,NDUFA12,POLR3GL,GTF2F2,UCK2,SMN1,UPRT,ATP5F1A,PNP,COPS2,NDUFS8,POLR2D,PMM2,FOXP3,DLAT,HSP90AB1,CBFB,CD28,NME4,CDKN2D,POLR3F,NCAPG2,GTF2A1,POLR3H,NDUFS3,LIG3,MED27,ATP6V1A,ADCY3,PAX6,MED29,GPBP1L1,GMDS,MAD2L2,GFPT1,SNAPC3,ADSS2,WNT10B,ELOVL7,AK2,DCAKD,POLR2I,WDR82,APOBEC3F,ATP5PO,DTYMK,CDC73,ZMPSTE24,HDAC3,IRF9,PAAF1,THAP1,MTAP,NDUFC2,TAF5L,GUK1,CREBL2,TAF2,PRPSAP1,SMAD2,GTF2H4,MSX1,MED9,TEX12,TRMT112,POLD2,TAF9,PHB1,PPP1R1B,MED23,ELOC,SHMT1,PPT1,UCKL1,TCEA1,NDUFA5,S100A10,EAF2,HINFP,PKNOX1,SGF29,PCLAF,POLDIP2,FOXA3,ATP5MK,NME2,MED11,GTF2A2,MED22,GFUS,APOBEC3C,SSU72,PPAT,MED30,BCL6,PLAC8,MED10,PIR,NFKB1,TERT,GUCY1B1,GTF2E2,NDUFB5,ATP5F1D,RB1,ELOVL1,OGG1,SUPT3H,TYMS,TFB1M,FOS,MED4,NPPC,NFYA,SUPT5H,TFCP2,DCTD,WBP2,SPHK2,UCK1,POLR2B,CDK9,ELOVL6,RPAP2,SDHB,UMPS,ACAT1,PDHA1,CCNH,MRPL12,APOBEC3A,NUDT12,NDP,CEBPG,LDB1,GTF3C3,NDUFV2,ELOF1,SUPT4H1,MEF2A,EPOP,VPS72,ADRM1,NCBP2,DDX5,TAF10,ATP5PB,TAF7,DTL,ELOVL3,NMRK1,APEX1,MED17,TP53,IDO1,ERCC3,GMPS,NDUFS2,ADK,ATP5MC3,COX11,KLF4,TCOF1,POLR1B,POLR2G,SQSTM1,POLR2F,POLR1H,POLE3,ATF4,UGDH,NDUFB10,NME1,HELT,NDUFAB1,ATXN1L,MTHFD2L,PTGES3,GTF2H2,SMARCA5,WRAP53,SRC,ACSS2,DRAP1,GTF3C4,GTF2I,TCEA2,CMPK1,AK3,ATP5F1E,PRIM2,GNPDA2,NDUFB4,NR4A2,GTF2E1,MNAT1,POLR2L,RRM1,HACD1,BCL9,IVNS1ABP,SMARCB1,EGR1,SNAPC2,NIBAN2,PPARG,MLF1,POLE4,AK5,ELOVL4,SLC52A3,DEK,LIPA,GMPPB,CCNA2,PAPSS2,NDUFB8,SDHC,GNPDA1,GTF2IRD1,PIK3R1,NDUFS6,IRF1 |
| 2.041e-06 | -13.10 | METTL3 (methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit) | protein interactions | 56339 | 278 | 114 | 19454 | 5460 |
TSEN34,ELOC,GAPDH,MOV10,AKAP8L,DNAJC7,RPL24,SNRNP70,OLFM2,SMAD3,SYNCRIP,CDK9,TMPO,TOP1,DDX39A,EEF1A1,CCT5,PSMC3,ILF2,ACTR2,PTGES3,MSH6,THRAP3,HNRNPK,HUWE1,LSM4,TUFM,NONO,ATP5F1A,SMAD2,EIF3G,ALB,ACAT1,PSMC5,EIF4A3,STUB1,VIRMA,TXN,EIF3J,NDUFAB1,GTF3C4,KCNH1,RPS14,PSMC4,WTAP,METTL14,LMNA,RPA2,MTDH,H2BC12,INPPL1,RPA3,HSPA5,EIF4E,GTF2I,DGCR8,TBC1D10C,RPL23,VPS4A,HNRNPD,LYZ,CSTA,CEP19,HSP90AB1,CCT7,TCP1,CCAR2,SNRPD3,SNX2,MPP1,EEF2,ZRANB2,UCKL1,TUBB4B,BAG2,RUVBL2,DNAJB4,EWSR1,CCT8,HSPD1,CBLL1,RUVBL1,RBBP7,HNRNPF,KRAS,BAG3,MLF2,BRMS1,RBM15B,SNRPB,MCM3,PRPF31,RNF40,CUL2,MYC,RIT1,DNAJB6,RPS26,HSP90AA1,CCT2,PRMT5,USP5,POLR2B,DYNLL1,TUBB,ACTB,MATR3,PRDX2,WDR77,EIF4B,DDX5,HSPA8,PSMC1,SRSF2 |
| 2.041e-06 | -13.10 | BASP1 (brain abundant membrane attached signal protein 1) | protein interactions | 10409 | 278 | 114 | 19454 | 5460 |
COPS5,LAMP3,HDAC6,CALR,PGAM1,RAC2,SYNCRIP,CD274,STX6,LMAN1,DKC1,CAV1,ARF6,MIF,TBK1,PSMC3,ACTR2,GAD2,EMC2,SFXN1,FKBP8,HSPE1,RAB3B,ATP5F1A,DNAJC5,RAB2A,AKT3,NRP1,NCKIPSD,TRIM24,UBB,VIRMA,RHOJ,CDC42,FTH1,RPRD1B,HSP90B1,PGK1,RAB9A,BAP1,RHOU,PPM1G,INPPL1,SOD1,HSPA5,CRYZ,NUCKS1,XPO1,PPIB,YWHAH,PDIA3,LAMP2,ISX,RAB5C,YWHAB,RHOG,GJA1,COPS2,WDR6,RAB35,DIRAS3,HMG20A,HSP90AB1,COPS7B,AFAP1L2,RHOH,OSBP,SUMO2,OTUD6B,MSX2,B3GNT2,ANP32A,RND3,NIM1K,RAB4A,CHMP4C,BCKDK,ANP32B,COPS4,FLOT1,KRAS,HNRNPF,TRIM37,MAP3K21,MYC,RAB11A,VMP1,LAMTOR1,CKB,RHOB,ATP6AP2,APEX1,ESR2,PSMD4,TRIM29,DYNLL1,PRDX3,PPP1CB,RND2,WDR77,TPD52L1,PIH1D1,PLAA,ATP5IF1,AKAP1,RAB5A,PEBP1,DDX39B,RPS28,STX7,FTL,G3BP2,EMC1,STAU1 |
| 2.042e-06 | -13.10 | SETX (senataxin) | protein interactions | 23064 | 150 | 69 | 19454 | 5460 |
PAK2,SUMO1,ARHGAP1,RFXANK,FAXC,CD2AP,NPTN,PIAS1,TRIM52,MEF2A,VPS28,CLU,PML,SQSTM1,NUBP2,PSMD14,BRCA1,COP1,THTPA,MYC,GPR17,SNRNP40,TUBB,MAD2L1,GADD45G,VIRMA,ESR2,LURAP1,CIB2,ZMYM2,PPM1M,PTEN,ALB,UBE2I,POLR2F,SIGLECL1,TUBB4B,EZH2,PNMA2,TOPORS,POLR2G,COMTD1,RAF1,SUPT5H,RIGI,PTGES3,SSRP1,SMN1,TFPT,GADD45A,EFNB1,CCL4L1,UBXN6,WWP2,NOL4,PPIB,YWHAH,ACTL6B,ANKRD10,SUMO2,EGLN3,CNTROB,CIB3,CITED1,CDC5L,LCN15,EEF1AKMT3,WDR82,TSG101 |
| 2.054e-06 | -13.10 | SPOUT1 (SPOUT domain containing methyltransferase 1) | protein interactions | 51490 | 131 | 62 | 19454 | 5460 |
EZH2,RRM1,CSNK1E,RAF1,TOP3B,E2F4,MIR15A,MIR200C,MIR222,H1-6,KRAS,MIR155,MIRLET7C,MIR200A,TCOF1,RPL3,SNRNP70,MIR1-1,MIR221,MIR34A,TSNAX,KARS1,CENPP,MIR143,DDRGK1,MIR9-1,MIRLET7G,MIR429,DKC1,MIR106B,EED,MIR141,MIR214,MIR25,DCTN4,GRM2,MIR21,MIR7-1,ACACA,MIR34B,STAU1,MIR29A,UTP23,MIR106A,SNAPC1,MIR205,PRPF4,MIRLET7I,MECP2,ATG3,PIP4K2C,MIR145,H1-1,RIT1,MYC,H2BC9,ATP5F1A,MIRLET7D,ESR2,TACO1,MIRLET7B,CSNK2B |
| 2.059e-06 | -13.09 | GOLGA3 (golgin A3) | protein interactions | 2802 | 223 | 95 | 19454 | 5460 |
DERL1,RAB9A,RETREG2,TOMM20,SMC4,KDM1A,ZSCAN1,ATG16L1,SSR1,FGFR1,GSK3A,TUBA1B,RPS3,VIRMA,JUNB,TRAF1,SMURF1,ADRM1,MGST3,DNAJC5,CIAO1,RAB2A,SMARCA5,UBE2H,EPHA2,NRP1,HAPSTR1,PPP1R12A,FKBP8,RAB3B,MTCH2,TBK1,FURIN,HSD17B11,ARL10,PTPN1,SYNCRIP,PLGRKT,CAV1,TMPO,STX6,DNAJC1,LAMP3,TMA16,SLC25A46,DPP4,KXD1,USP15,TSNAX,RAB5A,AKAP1,EXD2,PXMP2,STX7,STAU1,UFL1,RND2,SEC62,BET1,TOMM22,ANAPC2,SEC61B,PHF21A,RBBP4,PSMD1,HNRNPC,RAB11A,PSMD14,LAMTOR1,UBE3A,TMT1A,GOLGA7,AHCYL1,SAR1B,RUVBL1,LGR4,TRAF2,DNAJC25,TAF10,MTA2,RAB4A,PTRH2,PDHA1,KRT8,GJA1,RAB35,COX14,DIRAS3,CNTROB,KIF3B,INSYN1,NDC80,MARCHF5,RAB5C,LAMP2 |
| 2.074e-06 | -13.09 | DUSP4 (dual specificity phosphatase 4) | protein interactions | 1846 | 115 | 56 | 19454 | 5460 |
TMOD3,ADRM1,TECR,UBE2L3,TNPO3,GNAI2,TRAF1,GNG12,CTNNA1,PSMC5,ABHD14B,RNF187,EPCAM,ZNF655,PSMD14,CRMP1,NUDT1,PSMD1,GORASP2,SRM,GNB4,HSPA5,G3BP2,DDX39B,GID8,PSMA3,PRDX6,NUP50,JUP,PSMC4,SF3A1,CD59,PLEKHF2,LYAR,CCAR2,PPIA,EEF1AKMT3,MAP2K6,PSMB5,DUSP6,PSMB4,CORO1C,GATD3,PSMD7,HSPB1,PSMD3,AMY2B,HSPB8,PSMA1,PSMA2,HSPD1,MYO1B,ACTR1B,ACTR2,PSMC3,MTCH2 |
| 2.144e-06 | -13.05 | protein-RNA complex assembly | biological process | GO:0022618 | 200 | 90 | 18204 | 5365 |
EIF3J,NOP53,EIF2D,DHX9,CLP1,BRIX1,ZNHIT6,PRMT5,LSM4,SF3A1,EIF3D,WDR77,SF3B1,GEMIN8,RPSA,SRPK2,SNRPD3,RUVBL1,LSM2,MRM2,TAF9,SNRPD1,PRPF31,SART3,RPS28,XRCC5,SF3B5,TXNL4A,DICER1,PPAN,COIL,RBM5,SNRPD2,PRPF19,GCFC2,RPF2,SNRPA1,CD2BP2,SNRPE,RPL6,EIF3G,PRPF18,PIH1D1,RRP7A,MRPS7,SNIP1,ZNHIT3,PTGES3,GEMIN7,SRSF1,SNRPB,SRSF12,TRAF7,SF3B6,RPS15,SMN1,USP39,PWP2,EIF2S2,LUC7L3,SF3B4,RBMX2,TSSC4,HSP90AA1,RPS14,DDX42,SNRPB2,DDX1,NLE1,DDX23,SLU7,AGO1,DDX39B,RPL23A,PRKRA,DDX46,RPL10,NOPCHAP1,EIF3K,RPS27L,SNRPG,RPL10L,EIF3E,KHDC4,RPLP0,SRSF10,CELF6,RUVBL2,HSP90AB1,RPS5 |
| 2.158e-06 | -13.05 | mitochondrial matrix | cellular component | GO:0005759 | 494 | 191 | 19108 | 5553 |
OAT,ABHD10,TP53,PMPCA,MRPS23,NUDT9,TWNK,PDE12,DTYMK,MTG2,MRPL9,HADH,PDHB,ISCU,PYROXD2,TUFM,PPTC7,PDP2,DUSP21,SLC25A5,AMT,NDUFS2,GLRX5,MRPL16,ABCE1,MRPL24,GPX1,MRPS9,MRPL51,MRPL57,MTHFS,ARL2BP,ETFBKMT,PCCB,LDHAL6B,IDH2,GRPEL2,MRPL41,AK3,UQCC2,KARS1,GRSF1,HSD17B10,PDSS2,GRPEL1,PDHA1,PHYKPL,OGDHL,MRPL12,ACOT13,GLYAT,MRPL17,MRPL49,CYP27A1,ATP5F1D,MRPS34,AURKAIP1,COX10,NDUFB8,RPS3,NDUFS3,ACADS,TST,SDHAF4,PYCR1,REXO2,TRMT5,MRPS35,HAX1,NDUFS8,MRPL10,DBT,MTRES1,LIPT2,METTL15,MRPS18C,MRPL50,MPG,ACSS2,SDHAF2,OGG1,ETFA,GLRX2,STAR,SOD2,HSPE1,MCAT,MRPS18A,PYCR2,PCK2,PRDX3,NUDT1,HADHA,MRPL20,ATP5F1A,EXD2,SDHAF1,MMAA,HSPD1,MTERF2,MAIP1,MRPL33,MTG1,MRPL23,MTHFD2L,PPM1K,MRPS33,POLDIP2,MRPL34,DLST,CCNB1,MRPS28,MRPS25,PTPN1,MRPL13,BOLA3,SSBP1,SUCLG2,ATP5PB,CBR4,FXN,TERT,MRPS11,NME4,TFB1M,ACP6,ARG2,SHC1,MRPS26,DLAT,RNASEL,CDK1,TYMS,MRPS18B,IDH3B,IDH3A,HSD17B8,CHPF,VDAC2,MRPL22,LIAS,FAHD1,MPST,NUDT2,MRPL11,GFM2,MRPS21,GFM1,VDAC1,MRPL36,AUH,ACAT1,ATP5F1E,CCAR2,MRPL53,BCL2L1,ACAA2,ACADSB,SMDT1,CHCHD1,ISCA2,NDUFAB1,TXNRD2,MMUT,OXCT1,ATP5F1B,CLPX,MRM2,PABPC5,DNAJC19,PPIF,BCKDK,MRPL18,MRPL40,PDE2A,ACO2,MYG1,MECR,ETFB,FASTKD5,MRPS16,GSTK1,MALSU1,NGB,MRPL52,SOD1,PC,MRPS17,MRPL47,MPV17L2,MRPS7 |
| 2.162e-06 | -13.04 | U2-type spliceosomal complex | cellular component | GO:0005684 | 94 | 49 | 19108 | 5553 |
ZMAT2,SNRPN,TXNL4A,SF3B1,SNRPD1,LSM3,SNRPB,SNRPD3,DDX46,LSM5,MAGOHB,CDC40,SNRPG,EIF4A3,SNRPB2,CWC15,CDC5L,IK,PRPF4,LSM2,SF3B6,SMU1,RBMX2,SNRPA1,BUD31,SF3B5,SF3A1,SF3B4,PRPF18,LSM8,GCFC2,SNRNP40,CASC3,DDX42,LUC7L3,SNRPE,PRPF31,PRPF19,RBM22,LSM4,RNF113A,DHX15,SNIP1,SNRNP70,DHX16,SNRPD2,LSM6,MFAP1,TFIP11 |
| 2.164e-06 | -13.04 | NDUFAF1 (NADH:ubiquinone oxidoreductase complex assembly factor 1) | protein interactions | 51103 | 142 | 66 | 19454 | 5460 |
TMEM208,MTRF1,TMEM70,MRPS26,PPP2CB,SSBP1,GATD3,FAHD1,STARD3NL,SPPL3,RMND1,SLC25A12,TMEM97,MRPL11,METTL15,PPP2R1A,FAF2,APOO,PDHA1,NDUFS3,FURIN,NDUFA12,NDUFB5,HSPD1,STX8,LPAR2,HINT2,DNAJC30,COA1,IMMP2L,FASTKD5,PMPCA,MRM2,GPBAR1,KDSR,MTG2,AUH,TUFM,FAS,RIT1,CCDC90B,SCAMP2,S1PR4,TACO1,GPR173,SYNGR1,RETREG3,NDUFAF4,B4GAT1,PARL,TIMMDC1,NDUFAF3,MMP28,MTRES1,EXD2,AMACR,TSPAN15,GFM1,TMEM126B,STK26,NDUFC2,VIPR1,LPAR1,GRPR,SLC25A51,HSCB |
| 2.183e-06 | -13.03 | positive regulation of tumor necrosis factor superfamily cytokine production | biological process | GO:1903557 | 113 | 57 | 18204 | 5365 |
TLR9,IFIH1,PIK3R1,SETD4,TLR2,CD14,MIR206,MYD88,LILRA2,CCL19,CCR2,MIR657,PSEN1,TLR1,TYROBP,RIGI,TICAM1,JAK2,SPHK2,MAVS,TIRAP,IL23A,CD36,OAS1,SYK,CLU,HMGB1,SASH3,MIF,CCL3,BCL10,DDT,DHX9,FCGR2B,PTPN11,AGER,PYCARD,IFNGR1,TLR4,LEP,CD2,IL17F,TLR3,IL1A,AKAP12,IL12B,IFNG,MIR144,FCGR2A,IL6,CLEC7A,FRMD8,CD86,TMEM106A,HSPB1,LY96,SELENOK |
| 2.187e-06 | -13.03 | CD79A (CD79a molecule) | protein interactions | 973 | 255 | 106 | 19454 | 5460 |
PTPMT1,ODR4,VAMP3,CDIPT,TECR,SLC25A4,SLC35B4,HMOX2,REEP6,TMEM243,TMEM254,RAB29,ORMDL1,SLC39A9,SLC7A1,NME4,PLP2,SEC22B,TRAM1L1,EDDM3B,ATG16L1,FCAR,SLC12A2,GHITM,FA2H,IER3,HCLS1,FUNDC2,CNIH1,VTI1B,TMBIM6,SLC41A1,CD81,TMEM107,TMEM19,SLC13A5,ADGRE2,BTN2A2,ZDHHC15,TMEM42,TMEM11,DOLK,YIF1A,STX8,RDH11,FKBP8,ADIPOQ,METTL15,UBIAD1,YIPF4,INSIG2,JCHAIN,SFTPC,TMEM229B,FZD6,CD79B,PNMA1,THBD,HACD4,CYB561D2,MTG2,TM4SF19,FAXDC2,SLC38A1,CYB561,EMP3,CLDN1,JAGN1,CTXN3,CCDC167,EHD1,AGTRAP,BET1,SYK,FDFT1,CMTM7,SMCO4,SLC6A12,VAPB,SLC66A2,MFSD5,TMEM97,TSPO2,FATE1,EMC6,SYNJ2BP,RPL23,C2CD2L,FAM241B,DEGS1,TMEM147,SLC2A8,SACM1L,PLPP6,LEPROTL1,USP30,GJB1,MFSD6,TMEM176A,PGAP2,NEU1,TMEM14B,CYB5B,STX12,AQP3,CTSA |
| 2.196e-06 | -13.03 | Chemokine receptors bind chemokines | REACTOME pathways | R-HSA-380108 | 48 | 31 | 10285 | 3229 |
CCL1,CXCR4,CCL21,CXCL1,CCL5,CCR1,CCR5,CCL19,CCL28,CXCL3,CCR4,CCR7,CCL20,CCR6,CXCR6,CCR2,CXCL12,CXCL9,CX3CR1,CX3CL1,XCL1,ACKR3,CXCL11,CXCL10,CXCL8,CCL27,CXCR1,CCR3,CXCR3,CCL25,CXCL13 |
| 2.199e-06 | -13.03 | RBM17 (RNA binding motif protein 17) | protein interactions | 84991 | 209 | 90 | 19454 | 5460 |
RAF1,SMNDC1,SNRPE,SF3B5,HSPD1,MIR155,KRAS,CCAR1,WWP2,CTNNB1,DDRGK1,XPO1,SKIC8,DDX23,POU5F1,RBM5,SRSF1,TRIR,COMMD6,SNRPA1,SNRPD3,HNRNPL,RPS10,DHX15,LNX2,MFAP1,DDX39B,EP300,COMMD2,HSPA8,SF3B1,SAT1,STAU1,UFL1,CUL3,MYC,SNRPB,SF3B4,SNRPD2,SNRPD1,RPL35,SNRNP40,ESR2,SNRPB2,HINFP,DDX42,SNIP1,DHX9,EMC2,TOLLIP,CTNNBL1,MDC1,SNRPG,RBM17,CSNK2A1,SNRNP70,RPS2,ACTA2,ALYREF,MIR106B,MIR25,MIRLET7G,FZR1,CWC15,CDC5L,DKC1,SF3A1,GTF2H4,SAP30BP,RBFOX2,RPA2,MIR21,RPA3,SNAPC1,DDX46,MIRLET7I,MIR107,SUGP1,PPP1CC,DNAJC8,AR,UBE2H,CCHCR1,SF3B6,CCNF,RPS3,CSNK2B,YES1,SRPK2,SMURF1 |
| 2.200e-06 | -13.03 | UBE3C (ubiquitin protein ligase E3C) | protein interactions | 9690 | 192 | 84 | 19454 | 5460 |
VAPB,PSMB7,RPA2,RSAD2,HSP90B1,FAM3C,ANXA7,PSMC4,FAM234A,PGRMC1,PSMB3,GABRA1,HCST,CFTR,KDM1A,UBE2D3,PEBP1,VIPR1,EP300,BRCA1,PSMD14,NTRK3,UBE2H,PSMB2,USP13,MYC,CCNB1,CUL3,ATP5F1A,PSMD1,PSMD4,ADRM1,PSMD6,PSMB6,UBE2L3,VIRMA,CCNF,SCN2B,CD79B,PSMA6,PSMC5,ALB,CAMK1,MTA2,STK16,PSMC3,TOP3B,RRM1,IL1R2,FAF2,APOO,EEF1A1,MAP1LC3B,CLEC2B,EEF2,SEM1,PSMA2,PSMA5,TNFSF8,PSMA1,DNAAF10,HNRNPK,FN3KRP,PSMD12,RAD21,FAF1,UBE3A,UBE2D1,SMAD4,PEX3,GRSF1,PSMD3,CALR,PDIA3,ICAM2,HNRNPL,KCNMB2,TOP1,DYNC1I2,CCT7,CD274,THOC2,PSMB4,PSMB1 |
| 2.201e-06 | -13.03 | TMEM43 (transmembrane protein 43) | protein interactions | 79188 | 153 | 70 | 19454 | 5460 |
CD63,FBXO32,SRSF1,RMND1,DNAJB9,ARL6IP5,SPPL3,GPRASP2,DDRGK1,IFI16,PCYT1B,CFC1,FAM20C,EMC4,RB1CC1,ARMC8,BCL10,SLC2A1,EMC2,PSEN1,FKBP8,RIGI,RNF26,TMEM59,FAF2,ISG15,YIPF3,TOR3A,E2F4,VAC14,OTULIN,RPN1,BZW2,SFTPC,SEC61B,CCNF,ESR2,VIRMA,SIAH1,ZCCHC12,GGH,TM4SF20,OST4,RAB11A,EXOC8,MCAT,UBE2H,REEP6,ZMPSTE24,SDF2L1,ENDOD1,SYVN1,RTN4,GRAMD2B,RPA3,TMEM106B,TSPAN5,DAD1,UFL1,EMC1,TMEM106A,OTULINL,CFTR,CAV2,FDFT1,VAPB,RPA2,LMNA,SYNDIG1,UBAC2 |
| 2.205e-06 | -13.02 | Degradation of GLI1 by the proteasome | REACTOME pathways | R-HSA-5610780 | 61 | 37 | 10285 | 3229 |
PSMA6,PSMB3,PSMB2,PSMD1,PSMB6,PSMA2,PSMB10,PSMA5,PSMB11,PSMC5,PSMA4,SUFU,PSMC4,PSMC1,PSMD12,PSMB5,PSMA3,PSMB1,PSMB7,PSMD3,PSMD4,UBB,RPS27A,PRKACB,UBA52,PSMA1,PSMD14,PSMC3,PSMD7,SEM1,PSMB9,PSME1,PSMB4,SKP1,PSMD6,PSMD10,PSME2 |
| 2.207e-06 | -13.02 | Post-translational protein modification | REACTOME pathways | R-HSA-597592 | 1034 | 391 | 10285 | 3229 |
ADRM1,H2AC13,UBE2K,F7,BECN1,RAB9B,B4GALT4,DERL1,BABAM1,UBE2N,F10,H2AC6,STT3A,UBE2D3,USP3,RAB8B,TP53,RAB5A,RAB33A,RPS27A,BGLAP,RNF146,GALNT2,RAB6A,USP5,NLRP3,GPIHBP1,B4GALT1,METTL21A,BRCA1,RIGI,UBE2I,GMDS,SAR1B,PSMA5,RAB35,USP14,DCTN4,PSMB3,SCFD1,TMEM115,RAB6B,DOLK,GRIA1,H2AC1,SEC13,SRD5A3,UBE2S,SMAD3,TAF10,EIF5A2,RABGGTB,NFKBIA,CETN2,RAB5C,EEF1A1,NUS1,NUP107,PTRH2,SMAD1,TADA3,CTSA,PIGK,NEDD8,MYC,H2BC1,TOMM20,SPON1,RAD23B,MGAT4B,RAB31,RNF128,WDR20,DCTN6,PSME2,MGAT4A,THY1,DPH3,MIR711,H2BC17,NAPG,CTSC,RNF139,ACTL6A,RAB23,OTULIN,PCGF2,DPH6,KDELR2,NOP58,BET1,B4GALT3,GFUS,UBE2A,DERL2,HSPA8,GOSR1,ADAMTS10,GALNT4,PRND,ST6GALNAC3,RAB11B,CD59,MUL1,PSMD1,RAB13,ARFGAP1,FURIN,BCL10,ST8SIA4,USP30,ST3GAL4,DYNC1I1,SMAD4,PSMA1,TRAPPC6A,SEMA5A,TUSC3,RAB39B,TRAPPC6B,SUMO3,UFD1,SEC22B,PREB,GOSR2,UBE2H,TOMM70,H2BC14,H2AC25,RAB3B,PTP4A2,PIGC,FUT8,INO80E,RNF20,F9,MAVS,MDC1,COPE,CMAS,SENP5,GGCX,CNIH1,NEGR1,IDE,IZUMO1R,VDAC1,EDEM2,ADAMTS20,SPRN,DHPS,RNF181,HNRNPK,NUP37,USP16,RUVBL1,CALR,POMT2,H2AC14,RAB2A,TFPT,ETFBKMT,DPM2,H2BC9,BET1L,BIRC2,PIGW,TFG,HGS,NUP153,RAB3C,NRN1,PSMA4,GMPPB,RWDD3,SLC17A5,UBE2E3,PSMA2,PSMB6,PSMB1,CDC20,EEF2KMT,PSMC4,STX17,SUMO2,SIAH2,RNF5,RAB27A,NSMCE3,PSMD14,STX5,ETFB,RING1,SERPINA1,PMM2,UBE2B,SPTBN1,RAB29,MAN1A2,ALG5,GALNT17,SLC35C1,STAMBPL1,PSMA6,ST3GAL2,GNPNAT1,TRAPPC10,ST8SIA5,USP13,DPH5,ARF4,PHC1,PDIA3,EEF2,METTL22,LMAN1,TRAF2,RAB22A,C1GALT1C1,PSMC3,AR,TOP1,PSMB4,LHB,SEC23A,RAB18,ADAMTS1,SEM1,MAT2B,GCNT3,RNF40,ARF1,RAB3A,DNAJC24,RCE1,TRAPPC3,STAMBP,DYNC1I2,UCHL3,MDM2,RAB19,VCPKMT,TGFBR2,LY6G6C,UBA52,PIAS1,EP300,OTUD7B,RAB4A,RNF103,PIGA,RAB3D,INO80C,JOSD1,SEC22C,H2AC7,CD52,PCNA,CCNA2,NEU1,NUP35,RAB37,PSMD6,GFPT1,MITF,UBE2D1,TNKS2,MPDU1,DPAGT1,PSMB10,PSMC5,UBE2W,SMAD2,POLB,TNKS,OS9,PSMB7,PSMD3,UAP1,MIR7-1,PSMB5,PSMA3,MBD5,ST3GAL1,TRAPPC4,SYVN1,COG1,B4GALT6,GALNT1,ALPL,YKT6,IFIH1,USP15,PSMD7,TMED3,RAB11A,ALG11,SUMO1,PSMB2,NUP42,FOLR2,DOHH,PSMC1,SNX3,FOLR1,GPAA1,MVD,PSMD4,LARGE1,RAB32,GMPPA,RAB33B,RPN1,SLC35A1,H2AC4,KDELR1,B3GNT2,NUP62,PTEN,ARCN1,SPTAN1,HNRNPC,SENP8,TAB1,BIRC5,PROS1,ACTB,RAD21,TMED7,F2,RAB14,GANAB,ST3GAL5,PSMD10,MIA2,PML,CHST10,SKIC8,TMED9,COPZ2,CDC73,ARFGAP3,RRAGA,TRAPPC1,RNF152,CFTR,TNFAIP3,PSMD12,FPGT,RAB30,USP2,DYNLL1,EDEM3,ALG2,TRAF6,EDEM1,NANP,PSMB9,SEC22A,B4GAT1,DAG1,LY6H,CEACAM5,PSMB11,DCTN3,KIN,DAD1,H2BC11,VDAC2,NUP50,BAP1,RAB1A,ADRB2,RAB1B,MGAT1,ST6GAL1,NAPA,FN3KRP,TRAPPC2L,RPS2,NTNG2,UBE2L3,UBE2G2,TOP2B,UBB,GALNT12,RAB9A,PSME1,FKBP8,USP8,H2BC12 |
| 2.210e-06 | -13.02 | DNA Replication Pre-Initiation | REACTOME pathways | R-HSA-69002 | 86 | 48 | 10285 | 3229 |
RPS27A,PRIM2,PSMD4,MCM3,PSMC3,PSMA1,PSMB9,SEM1,ORC6,RPA3,PSME2,PSMD6,PSMB4,PSMB2,PSMD1,PSMA6,CDC7,POLE4,PSMD12,POLA2,PSMC1,MCM8,UBA52,UBB,PSMD14,GMNN,POLE3,PSMD7,PSMD10,PSME1,MCM6,PSMA2,PSMB6,RPA2,PSMB3,PSMA4,MCM4,PSMB11,PSMC5,PSMA5,PSMB10,PSMB5,PSMA3,ORC5,PSMC4,PSMD3,PSMB7,PSMB1 |
| 2.210e-06 | -13.02 | M/G1 Transition | REACTOME pathways | R-HSA-68874 | 86 | 48 | 10285 | 3229 |
CDC7,PSMA6,PSMB2,PSMD1,MCM8,POLA2,PSMC1,PSMD12,POLE4,PSMA1,PSMC3,PSMD4,MCM3,PRIM2,RPS27A,PSMB4,PSMD6,PSME2,RPA3,ORC6,SEM1,PSMB9,PSMB10,PSMA5,PSMC5,PSMB11,MCM4,PSMA4,PSMB3,RPA2,PSMB6,MCM6,PSMA2,PSMB1,PSMB7,PSMD3,ORC5,PSMC4,PSMB5,PSMA3,POLE3,GMNN,PSMD14,UBB,UBA52,PSME1,PSMD10,PSMD7 |
| 2.216e-06 | -13.02 | DNAJC21 (DnaJ heat shock protein family (Hsp40) member C21) | protein interactions | 134218 | 74 | 40 | 19454 | 5460 |
UBE2N,SRP14,MRPS23,RPL10,VIRMA,RPL19,CACYBP,FBXO22,PRNP,FZR1,CAND1,RPS16,ZNF622,H2BC9,RPL7A,WWP2,RPL6,H2AC14,PRDX1,HSPB1,DNAJB6,BPIFA3,DLAT,MRPS18B,TOP2B,MRPS7,MRPS17,GRPEL1,STAU1,RPL4,FBXW7,NUDCD3,TPT1,FBP1,RPL18,AAMP,PPP4C,RPLP0,VAV2,EZH2 |
| 2.229e-06 | -13.01 | DDX56 (DEAD-box helicase 56) | protein interactions | 54606 | 299 | 121 | 19454 | 5460 |
LHX2,DDX23,XPO1,DDRGK1,IFI16,NOP58,RPS10,HNRNPL,LYAR,RHOH,RPL8,MRTO4,SRSF1,RPS11,RPL18,SKA3,SOX2,RPL29,RAF1,TOP3B,MAGEB10,RPL28,H1-6,FAM76B,RPS24,RPL31,PPAN,RCL1,RIT1,H1-1,RHOB,MRPS25,FTSJ3,ZNF668,RPS29,RBM15B,MYC,CUL2,RPL10,MAD2L2,ESR2,APEX1,RPL7L1,RPL35,SNRNP40,RPL37A,RPS9,TACO1,MFAP1,NUFIP2,RND2,BET1,COIL,UFL1,STAU1,EP300,RPS2,MPHOSPH10,SNRNP70,PPIL4,COPS5,GRSF1,DKC1,CDK9,SURF6,CAND1,RPS16,DCUN1D1,TOP1,PRR3,RAC2,MRPS9,SRP14,KRR1,DDX42,RBM34,AURKAIP1,MEPCE,HNRNPK,RPL3,RPL23A,SNIP1,UBE2H,MECP2,RC3H2,RPL26,PRKACB,RPF2,RPL7A,CIAO1,PPP1R10,SRPK2,RPL13A,RHOJ,RPGRIP1L,PRKRA,FGFBP1,EIF2S2,PPP2R5E,CCNF,PSPC1,TNFRSF1B,ZNF330,CTTN,EIF4A3,RPLP0,MRPS34,RPA2,CDC42,FGF13,KLF12,CDK7,ATG16L1,AATF,BRIX1,DGCR8,NPM3,RPL4,RPA3,RPL27,SIRT7 |
| 2.239e-06 | -13.01 | negative regulation of viral process | biological process | GO:0048525 | 93 | 49 | 18204 | 5365 |
MIR141,OAS1,IFNB1,TRIM11,BST2,MAVS,STAT1,APOBEC3B,TRIM15,APOBEC3F,IFI16,BANF1,PLSCR1,IFNA2,TRIM26,CSNK2B,APOBEC3H,TRIM10,APOBEC3A,IFIH1,SLPI,EIF2AK2,SNX3,TRIM32,RSAD2,UBP1,TRIM62,PPIA,TRIM6,TRIM8,APOBEC3G,SRPK2,CCL5,TNF,RNASEL,HEXIM1,ISG15,TRIM21,PROX1,APOBEC3C,ISG20,TRIM5,TRIM27,CH25H,APOBEC3D,MBL2,MORC2,MX1,INPP5K |
| 2.251e-06 | -13.00 | HP1BP3 (heterochromatin protein 1 binding protein 3) | protein interactions | 50809 | 302 | 122 | 19454 | 5460 |
CAND1,RPS16,TOP1,MBD5,CDK9,TMPO,H2AZ1,SRP14,KRR1,PRR3,H2AC4,SNRNP70,BRD3,CSNK2A1,HUWE1,H3C1,VRK1,MEPCE,ARF4,FBXO25,RPL17,RPL3,SURF4,CBX3,LLPH,HBP1,NUPR1,IPO8,TP53,RPL13A,SMURF1,SRPK2,RPS3,CCNF,ZNF330,PRKRA,FGFBP1,ANAPC4,MAPRE1,RRP7A,UBE2H,DEPDC1B,RPL26,PPP1CC,USP14,DGCR8,NPM3,NUCKS1,FBXW7,RPL4,HMGB1,PIAS1,UTP23,RPA3,SIRT7,PML,RNF113A,MTDH,LMNA,RPA2,ZNF326,GRM2,HEXIM1,RPLP0,RPS14,KLF12,FGF13,HNRNPL,RPS10,SUMO2,HMG20A,PHB1,EED,AGR2,HMGA1,IFI16,LAMP2,WWP2,XPO1,DDRGK1,TRA2A,FGD2,H1-6,VDAC1,SRSF4,PPAN,RUVBL2,SRSF7,TRIM11,RPS24,EZH2,PDHA1,RPL18,SART3,TPBG,RAF1,E2F4,ISG15,MAK16,FBXO22,RPL35,APEX1,RPL10,DLST,RPS9,FTSJ3,BRCA1,ZCRB1,LMNB1,HSP90AA1,H1-1,MYC,NOP16,CUL3,RIOK2,UFL1,G3BP2,HSPA8,APOBEC3C,EMC9,SYK,H1-5 |
| 2.252e-06 | -13.00 | DOCK7 (dedicator of cytokinesis 7) | protein interactions | 85440 | 232 | 98 | 19454 | 5460 |
BAG2,KRAS,RBBP7,TRIM37,UBE2A,IMMP2L,COPS4,RAF1,SOX2,LGR4,MOB3C,WDR6,DNM2,RAB35,PPP2CB,COPS2,SOSTDC1,KRT8,COPS7B,EGLN3,HSP90AB1,IFI16,UBXN6,XPO1,YWHAG,YWHAH,YWHAB,BCL2L1,EP300,UFL1,STAU1,DUSP26,RPP14,CDKN1A,MED23,PPT1,PIH1D1,ANXA7,PHF21A,DYNLL1,ESR2,MYC,COPS7A,LDHB,SFN,CUL3,CKB,YWHAZ,FBXW11,MYO6,RHOB,DCAF4,HTRA2,PSME1,ERLEC1,TRIM63,CAPZA1,SMN1,TP53,ARPC3,CAPZA2,CAPN2,NUPR1,CD274,EEF1AKMT3,ARF6,PPP1R18,PRNP,MIF,PTP4A3,MOV10,COPS5,HDAC6,API5,BAP1,IRF3,SIRT7,RTN4,KDM1A,FBXW7,HSPA5,CDC42,RPA2,CCNF,CIB2,GTF2A1,GSK3A,DAPK1,TMOD3,DYRK1A,VIRMA,AKT3,CCNB1,ATP5F1A,USP14,CRLF3,NCKIPSD,UBE2H |
| 2.255e-06 | -13.00 | TRIM6 (tripartite motif containing 6) | protein interactions | 117854 | 57 | 33 | 19454 | 5460 |
VAMP8,RIGI,GTF2I,DHX16,STK38,TRIM5,HSPA8,LCN1,SLC25A5,RAB1A,ABCF1,GSTP1,EIF4B,LMNA,BTG2,GFPT1,EEF1A1,TRIM6,APEX1,HSP90AB1,ATP5F1B,LGALS3,PRMT5,ALB,RPS3,STUB1,CCT2,TRIM23,LGALS8,ATP5F1A,TRIM34,TUFM,MYC |
| 2.271e-06 | -13.00 | ATAD3A (ATPase family AAA domain containing 3A) | protein interactions | 55210 | 305 | 123 | 19454 | 5460 |
RPN1,PDHA1,CHMP4C,B3GNT2,RAF1,TOP3B,SOX2,LGR4,G3BP1,VDAC1,UBE2A,IMMP2L,S100B,NDUFA4,HINT2,COX8A,RHOG,PEX3,NDUFB8,PIK3R1,WWP2,MARCHF5,CPEB1,DDRGK1,CTNNB1,HNRNPL,RHOH,KCTD10,EGLN3,FBXO32,PHB1,KCTD12,MAP2K1,CSNK1A1,SLC25A3,MTF1,PPP2R2C,UFL1,HSCB,PHB2,STAU1,PXMP2,COIL,G3BP2,DDX39B,EXD2,HSPA8,AKAP1,LAMTOR1,RHOB,SP1,HTRA2,ILK,MYC,PMPCA,CUL3,BTF3,MATR3,PARL,BAD,LMBR1L,DLST,CCDC90B,TFCP2,PPP4C,NUPR1,MTCH2,APOO,DNAJC30,FASTKD5,PDE2A,FBXO25,MEPCE,MAP1B,SFXN1,PSME1,ESYT1,TMEM70,DNAJC4,FGR,NFKB1,DPP4,SLC25A46,ATP5MG,HDAC6,CDK9,TMPO,PTP4A3,SLC25A12,CD274,AIFM1,COX4I1,RPA2,GRM2,SSR1,HEXIM1,KLF4,MTRES1,CYC1,HECTD1,CDC42,GABRA1,CFTR,NF2,SLC25A51,DVL2,RPA3,SIRT7,SQSTM1,RNF113A,TXNIP,UBE2H,FBXO7,PPP1CC,TUFM,USP14,RHOJ,SEC63,VIRMA,UQCRC2,CCNF,PTPMT1,TRIM24 |
| 2.291e-06 | -12.99 | GOSR1 (golgi SNAP receptor complex member 1) | protein interactions | 9527 | 110 | 54 | 19454 | 5460 |
LAMTOR1,SCFD1,NAPA,VAMP5,RAB2A,CSGALNACT2,ESR2,APEX1,ATP6AP2,VAMP3,TMEM74,USE1,LMNA,PTP4A2,BET1,GOSR2,SEC22B,PTAR1,CHST7,GABARAPL2,CDK7,OTULINL,SLC35E1,ATAD1,RER1,PHB2,YKT6,STX7,BET1L,RAB9A,RAB5C,PLPP4,LAMP2,MIF,SNAP25,DYNC1I2,CAV1,STX6,KCNA2,PTPN1,HRAS,STX5,CTLA4,STX12,TRAPPC13,SNAP29,TMEM59,SRPRB,KRAS,SAR1B,STX11,STX8,BSCL2,STX18 |
| 2.301e-06 | -12.98 | UBXN1 (UBX domain protein 1) | protein interactions | 51035 | 195 | 85 | 19454 | 5460 |
EGLN3,KCTD10,IGBP1,ATP6V1A,FBXO32,DUSP6,EEF1AKMT3,VCPIP1,CD81,KLHL22,PRPF19,BMPR1B,UBXN6,BABAM1,VTA1,UBE2A,AHCYL1,PSMA1,HUWE1,UFM1,CSE1L,TAGLN3,UBE3A,FAF1,CAPN2,CDK5R1,RNF126,PSMC3,KLHL12,CTLA4,VAMP2,ACVR1,ISG15,FAF2,SMAD1,UBL4A,TXNRD1,CDK4,E2F4,SMURF1,UBE2V2,UBE2L3,PSMD4,UBE2I,SGTA,PTEN,OPTN,TNFRSF1B,FAS,MYO6,WDR20,BRCA1,UFD1,TUFM,CSK,EMILIN1,MYC,CUL2,CUL3,HSPA5,UNC45A,NPTN,HSCB,NSFL1C,HMGB1,PRKCB,BIRC2,HSPA8,TTC1,SQSTM1,MAVS,TNFAIP1,RLIM,STK26,YAF2,RPA3,PIH1D1,JUP,PLAA,VPS4B,RPA2,PPP1CB,CFTR,SEC22B,PAFAH1B1 |
| 2.301e-06 | -12.98 | CRBN (cereblon) | protein interactions | 51185 | 195 | 85 | 19454 | 5460 |
PRKAG1,APTX,ILF2,TP53,RPSA,CCT5,RAF1,JUN,RUVBL1,HNRNPK,PSMA2,ZBTB16,PRPS1,COPS4,EGR1,CCT8,HNRNPA2B1,GLUL,RTCB,PDIA6,BAG2,RUVBL2,SLC16A1,TRIM21,TRAF6,UBE2D1,POLB,AHSA1,POU5F1,CTNNB1,SUV39H1,HDAC6,COPS5,TCP1,SNRPD3,HNRNPL,COPS7B,HSP90AB1,COMT,PSMB4,COPS2,SPRYD4,PAK5,CSNK1A1,PIH1D1,ELF5,OSR2,RPL26L1,UBE2M,SNRPN,WDR77,CFTR,STK38,KDM1A,UBE2D3,ZNF692,BCL6,SKP1,TMEM263,RPL27,SQSTM1,DDX5,IVNS1ABP,BRCA1,KCNMA1,SENP8,HSP90AA1,PIK3R3,HNRNPAB,HNRNPC,COPS7A,SNRPB,ATP5F1A,RPL26,FBXO7,SPINDOC,RPL35,MATR3,ATP5F1B,TXN,APEX1,LIG3,ZMYM2,CMBL,SNRPD1 |
| 2.302e-06 | -12.98 | defense response to symbiont | biological process | GO:0140546 | 894 | 326 | 18204 | 5365 |
YTHDF2,IL23A,SAMHD1,BNIP3L,LYZ,LGALS3,TLR1,TICAM1,GAPDH,CYP27B1,IL34,IKBKB,SDHAF4,CNOT7,TRIM15,CXCL13,TLR8,NDUFAF4,OPRK1,IFI16,PPARG,SLC15A2,BPIFB1,APOBEC3H,ACTR2,NQO1,TRIM10,TRIM52,PQBP1,TNFAIP8L2,IRF1,IRAK4,CCL1,PRKRA,AZI2,IL21,CLEC7A,TMEM45B,CAMP,ENDOD1,LGR4,H2BC12,CD47,IL17F,CXCL8,FAU,SERINC3,TP53,SPAG11B,IFNG,HEXIM1,ZNF175,PHB2,CCL11,CD58,CCL8,SEC14L1,NONO,TFEB,TRIM21,REG1B,PIK3CG,RNASE4,TLR4,IFI6,FASLG,TRIM27,TMEM33,PRDX1,IL18,MIR26B,NT5C3A,SRC,TRIM35,CASP4,RNASET2,ARG2,CCL18,NFKB1,KCNJ8,CCL4L1,CGAS,CITED1,TRIM23,NLRP2,CXCL10,TASL,TNFRSF14,VAMP2,PSPC1,CCL2,LSM14A,SEMG2,PML,APOBEC3B,TUBB,CCL19,AIF1,TLR5,VAMP3,SFTPD,TIFA,F2,PLSCR1,TBK1,XRCC5,APOBEC3A,RARRES2,TLR2,TRAF6,CCL25,NLRP3,CEBPG,TICAM2,TLR10,TRIM32,NMBR,TUSC2,GPAM,KLRC2,DEFB115,TRAF2,CX3CR1,TRIM62,PDE12,VAMP7,PHB1,YES1,LY96,TRIM6,IFIT2,CD2,DEFB121,TNF,ATG16L1,SARM1,CX3CL1,RAF1,XCL1,S100A8,PYCARD,APOBEC3C,TRIM5,IL1RAP,SYK,CLU,CD1D,CH25H,HMGB1,NLRP1,MBL2,CCL23,OTULIN,CD40,OPTN,ZYX,PMAIP1,POLR3F,CDC42EP4,TAX1BP1,MSRB1,POLR3H,LYAR,CHID1,NCR3LG1,RIGI,SIN3A,TRIM11,IFI27,IFNB1,MAVS,CLEC6A,NMI,RNASE1,AQP4,CD46,APOBEC3F,LILRA2,DHX16,CLDN1,NLRP9,IFNA2,TRIM26,PLPP6,MIR146A,CXCL3,DNAJC3,ATG7,IFNK,TLR9,IFIH1,SLPI,IRF9,SYNCRIP,EXOC1,LEAP2,MYD88,WFDC5,JAK1,SH2D1A,CCL17,PI3,RTP4,IL6,RSAD2,PYDC2,CDC42,DAPK1,IFNAR1,IFNA10,APOBEC3G,CXCL9,G3BP1,CNPY3,CCL5,G3BP2,TRIM68,TLR3,RNASE6,FGR,POLR3B,DEFB124,RNASEL,IL12B,TREML1,FCER1G,DDX1,MX2,IRF3,STX8,AKAP1,IFNGR1,RPL39,DAPK3,CXCL14,VPS26B,TRIM34,APOBEC3D,MIF,BPIFB3,CCL3,MX1,BCL10,MATR3,PELI3,MOV10,TMED1,ELMOD2,LILRB1,FOSL2,LACC1,MAP3K14,MRC1,CHGA,IRF8,DEFB114,FCGR1A,REG1A,CCDC92,RAB27A,OAS1,BCL2L1,JAK2,H2BC11,NLRP6,STXBP1,TLR7,IRF7,USP14,BST2,STAT1,DHX15,TIRAP,TRIM29,BECN1,IFI35,ATP1B1,MIRLET7B,KLRD1,UBE2N,RPL13A,TRIM22,CDC42EP2,CYBC1,CCL21,TOLLIP,EXOSC4,CD14,FAM3A,EIF2AK2,STAT2,TUBB4B,DEFB1,DEFB116,HYAL2,CCL24,CXCL11,TMEM106A,TF,NCK1,TRIM8,SRPK2,ROMO1,CD209,UBE2W,FCN2,CLPB,FBXO9,UAP1,IFNA13,DDIT4,ISG15,TLR6,CCL20,CXCL1,JCHAIN,WFDC13,ISG20,HCFC2,TANK,ZMYND11,IRF2,VAMP8,DHX9,TTC4,C1QC |
| 2.303e-06 | -12.98 | glutathione peroxidase activity | molecular function | GO:0004602 | 23 | 18 | 18094 | 5411 |
GPX2,PRDX6,GSTK1,GPX6,GSTA1,GPX1,GPX5,PTGES,GSTT1,GPX4,GSTP1,MGST3,GSTM2,GPX7,CLIC2,MGST2,ALOX5AP,GPX3 |
| 2.317e-06 | -12.98 | PCBP2 (poly(rC) binding protein 2) | protein interactions | 5094 | 264 | 109 | 19454 | 5460 |
SLC7A11,RIT1,BRCA1,BTF3,MYC,CUL2,CUL3,LGALS3,TAX1BP1,UMPS,PIH1D1,APOBEC3C,PPT1,RALYL,WDR77,UFL1,ADRB2,STAU1,HDAC5,NMRAL1,HSPA8,PSMA3,EP300,COMMD2,SNRPA,SLU7,HNRNPD,AGR2,HNRNPA1,PPIB,DDRGK1,CTNNB1,PDIA3,HMGA1,IFI16,IFIH1,WWP2,SRSF10,HNRNPL,CCAR2,SUMO2,EED,FUBP3,PHB1,EZH2,CHMP4C,RAF1,E2F4,SRSF4,UTP25,KRAS,RUVBL1,RUVBL2,SRSF7,SCYL2,PABPC1,IGF2BP1,UBE2H,SPOP,RC3H2,BICD2,FBXO7,TIA1,ATP5F1A,AR,SRC,VIRMA,NDN,POLR3H,CCNF,OPTN,UBE2M,HEXIM1,WTAP,METTL14,GRM2,AGO1,FTH1,CFTR,RBFOX2,WDR83,CCND1,MAVS,RNF113A,BAP1,COPS5,CD81,HDAC6,TMPO,CDK9,CDC5L,FZR1,NKAP,CASK,NUPR1,RNF8,TFCP2,H2AX,DUSP1,EEF1A1,GNPNAT1,UBL4A,PSEN1,ARF4,MEPCE,RIGI,HUWE1,HNRNPK,MAP1B |
| 2.321e-06 | -12.97 | NDUFAF2 (NADH:ubiquinone oxidoreductase complex assembly factor 2) | protein interactions | 91942 | 126 | 60 | 19454 | 5460 |
TACO1,MTG1,CCDC90B,PTPMT1,SEC61B,PARL,VIRMA,MTG2,AUH,PMPCA,TUFM,LAMTOR1,RHOB,LMNB1,HSP90AA1,RPS26,UBE2H,DNAJC19,EXD2,RTN4,GFM1,HSCB,SEC22B,MTRES1,HRAS,SSBP1,AIFM1,COX4I1,GATD3,ARF6,TMEM97,CAV1,MTRF1,GRSF1,LAMP2,EMC4,NDUFV2,RHOG,CHCHD1,TMEM70,MRPS26,NDUFB8,STX8,HSPD1,NDUFA4,HINT2,COX8A,RPS24,KRAS,FASTKD5,IMMP2L,MRPL11,PPIF,SPG21,METTL15,CBLN4,PDHA1,ACOT13,GFM2,CYB5B |
| 2.321e-06 | -12.97 | PRR11 (proline rich 11) | protein interactions | 55771 | 126 | 60 | 19454 | 5460 |
MOV10,NOL12,RPL10A,KCNA2,KRR1,ARL10,HP1BP3,LYAR,DKC1,SURF6,RAF1,TP53,MTCH2,E2F4,FUT9,SOX2,RPL15,LLPH,GNPDA2,RBM34,RPL23A,RPL3,PAK1IP1,NOC4L,RPS13,MYC,RPF2,CIAO1,NOP16,ZNF668,ZCRB1,FTSJ3,ELAVL2,NSA2,H1-1,SORD,CASC3,ZNF22,RPS3,TNFRSF1B,ZNF189,PRKRA,SEC61B,RPL13A,RPL7L1,RSL24D1,SEC63,ESR2,ARHGAP1,RPL26L1,SF3B1,CCDC86,AKAP1,RPS15,RPL4,NOP53,STAU1,BRIX1,FTL,UTP23 |
| 2.349e-06 | -12.96 | WBP11 (WW domain binding protein 11) | protein interactions | 51729 | 145 | 67 | 19454 | 5460 |
PCBP4,EED,COPS2,SEC23A,RBM5,XPO1,MOV10,PIK3R1,ANKRD50,DDX23,EWSR1,RPL31,RUSF1,MAP1B,PQBP1,ARF4,CTNNBL1,LSM4,MAP1LC3B,CD2BP2,RAF1,H2AJ,SUPT5H,JPH4,NUPR1,EZH2,NGB,ARF1,EZH1,ZNF330,SRPK2,ESR2,SRC,TCEAL7,SNRPB2,ATP6AP2,CAVIN2,SNRNP40,IFI6,SPCS1,ANAPC15,PPP1CC,DNAJC8,RSPH1,MYC,PEA15,RIT1,RC3H2,LMNB1,EP300,NUP50,DDX5,HADHA,RPA3,PPM1G,PEBP1,PML,UPF3B,TESC,PSENEN,EEF1G,PPP1CB,MORN4,PRMT2,EHHADH,RPA2,LSM2 |
| 2.353e-06 | -12.96 | DCTD (dCMP deaminase) | protein interactions | 1635 | 28 | 20 | 19454 | 5460 |
MALSU1,CRYZ,DYRK1A,PSMA1,FXR2,FGF12,DYNC1I2,PICK1,PITPNB,UBE2I,NUDT18,NGRN,PEBP1,DCTD,MT1X,SOD2,NIF3L1,SDCBP,BRCA1,GORASP2 |
| 2.375e-06 | -12.95 | DHX57 (DExH-box helicase 57) | protein interactions | 90957 | 238 | 100 | 19454 | 5460 |
SYK,H1-5,RPL27A,PABPC5,LARP4B,APOBEC3C,EP300,HSPA8,STAU1,UFL1,FXR2,G3BP2,ZDHHC17,MYC,ZNF668,LMNB1,DCAF4,H1-1,RPS9,FBXO22,RPL10,ESR2,RPL19,PRRC2A,TOP3B,RAF1,H1-3,OTUD6B,SOX2,SART3,RPS11,FGF3,RPL31,CHCHD2,H1-6,IMMP2L,SRSF4,WWP2,IFI16,DDX50,DDRGK1,DRG1,SRSF1,LYAR,RPS10,TPT1,RPS14,RBMS2,FGF13,GRM2,RPA2,MACROH2A2,HEXIM1,RPL26L1,ZNF574,SIRT7,RPA3,FBXW7,RPL4,CLU,NONO,RC3H2,EIF3G,UBE2H,ATP1A1,RPS3,PSPC1,RPS20,FGFBP1,SRC,UBB,RPSA,RPL15,FNTB,SESN2,SRP72,HBP1,RPL3,RPL23A,RPL17,MEPCE,RPS13,MOV10,GRSF1,COPS5,ZNF473,SNRNP70,H2AC4,NOL12,RPS2,KRR1,SYNCRIP,PRR3,CGAS,RPS16,CAND1,FZR1,DCUN1D1,SURF6,RBM42 |
| 2.398e-06 | -12.94 | TCOF1 (treacle ribosome biogenesis factor 1) | protein interactions | 6949 | 270 | 111 | 19454 | 5460 |
GNL1,TNF,GUK1,RBBP7,RPL28,RPL31,PCNA,NUDT19,RAF1,MAX,LGR4,ANAPC13,NOP58,SRSF10,FOLR1,BRD9,EED,AK2,DDX23,RASSF8,WWP2,PRPF19,DDRGK1,XPO1,OXCT1,COX17,PPT1,PIH1D1,PAFAH1B1,SYK,SNRNP40,CAVIN2,APEX1,PSMB6,POLR2B,LMBR1L,DCAF4,BRCA1,POLR1B,ICAM1,MYC,HNF1B,BTF3,THRAP3,FGF12,CAMKV,RNASEL,RIGI,TCOF1,MAP1B,SNIP1,MSRB3,ATP5PB,TBK1,GLRX5,MAP1LC3B,TOP1,EIF2B5,FZR1,CAND1,CDK9,DKC1,ITK,ARL4D,BECN1,CD9,CSNK2A1,BCL6,POLR1H,MARS1,NHP2,NLE1,SIRT7,APMAP,BAP1,RPL27,RPA3,PPM1G,RTN4,MTDH,RNF113A,HSP90B1,GRM2,RPA2,TM9SF1,HEXIM1,SEC22B,GTF2H4,SF3A1,LIAS,CFTR,DENND2D,TXN,DYRK1A,SRPK2,DUSP10,VIRMA,SMURF1,CCNF,PRKRA,CSNK2B,PKNOX1,SPOP,UBE2H,FXN,ZBTB38,ATP1A1,CIAO1,NPTX1,AKT1,CDC16 |
| 2.401e-06 | -12.94 | SMU1 (SMU1 DNA replication regulator and spliceosomal factor) | protein interactions | 55234 | 198 | 86 | 19454 | 5460 |
IFI16,DDRGK1,XPO1,SNRNP70,TSNAX,PHB1,SRSF1,FBXO32,RPL9,DSTN,CAND1,FZR1,ZBTB2,SRSF10,E2F4,MTCH2,RAF1,TPBG,CD2BP2,NCSTN,IK,ACADSB,NUPR1,MTMR2,RPS11,ARB2A,HSPD1,MRFAP1L1,SLC25A10,PDIA6,HSD17B10,MRFAP1,RPL3,PCNA,FN3KRP,KDM4B,H3C1,TFPI,KRAS,LSM4,G3BP1,HUWE1,RPS4X,CUL3,PYCR1,HNRNPC,MYC,TUFM,AR,SNRPB,PCCB,ATP5F1A,RNF40,SPOP,RIT1,SERPINH1,UBE2H,OAT,UQCRC2,RPS12,SMU1,TXNDC12,MATR3,PRDX2,TXN,ESR2,CCND1,SF3A1,RPL27A,RPS14,UQCRC1,PRDX3,RPA2,LUC7L3,MFAP1,SIRT7,RPA3,SNRPA,EP300,SQSTM1,SF3B1,FBXW7,UFL1,UBE2D3,LSM8,SAP18 |
| 2.429e-06 | -12.93 | DNAJA1 (DnaJ heat shock protein family (Hsp40) member A1) | protein interactions | 3301 | 505 | 189 | 19454 | 5460 |
EEF1AKMT3,RCHY1,EFNA3,AIFM1,TES,ZBTB2,MRPS23,HDAC6,EID1,CRBN,DNAJC7,SFXN1,GARRE1,PPP1R12A,FAF1,IGF1R,HAPSTR1,THRAP3,HUWE1,PSEN1,FBXO25,TBK1,TM4SF1,BCS1L,MAP2K3,TUBA1B,STUB1,CCNF,UBASH3B,PTEN,TXN,VIRMA,UQCRQ,CSK,CDC16,AR,USP14,PPP1CC,FBXO7,CDC73,SIRT7,PPM1G,RPA3,MIS12,FBXW7,NF2,TPT1,CCND1,EEF1E1,ATG16L1,UQCRC1,LSM2,METTL14,GRM2,RARS1,RPLP0,PHB1,FOLR1,COPS2,SPTAN1,EGLN3,MARCHF5,PDIA3,PSMD10,CD58,AHSA1,HAX1,NDUFA4,BAG2,G3BP1,TNF,RBBP7,AHCYL1,HS2ST1,UBE2A,B3GNT2,RAF1,CHMP4C,EZH2,SART3,SNRPD2,TUBB,RBBP4,GPR37,CUL2,CUL3,BRCA1,ILK,NTRK3,HSP90AA1,PSMA3,CRY1,NMRAL1,PPP2R2C,FBXL4,NUDT3,DET1,OTULINL,PPARG,EEF1B2,ARL4D,FZR1,CDC5L,TMPO,MBD5,DPP4,COPS5,SHC1,H2AC4,SNRNP70,USP15,MAP1B,CSE1L,FKBP8,MTCH2,TP53,ACTR1A,DISC1,SELENOF,MACROH2A1,PSMC5,PHAX,ADRM1,PRKCE,SMURF1,ST13,RC3H2,UBE2H,ATP1A1,ZBTB38,PTTG1,BAP1,RNF113A,KDM1A,HSPA5,CFTR,GABRA1,HBB,FGFR1,RPA2,LUC7L3,ACACA,UBE2M,HEXIM1,DYNC1I2,SUMO2,PCSK9,PGR,ELK1,WWP2,CNOT2,DDRGK1,NT5C2,RUVBL2,RUVBL1,TOP3B,TNPO2,TUBA1A,SOX2,NUDCD3,PDHA1,HDAC11,TUBB4B,GLE1,MOB3C,LMBR1L,PRMT5,HNRNPC,LDHB,MYC,BTF3,PSMD14,LAMTOR1,CCT2,OSGEP,TMEM106B,AKAP1,HDAC5,HSPA8,EEF1G,STAU1,TRA2B,UFL1,FBXO42,PPT1,PIH1D1,CSNK1A1,CAV2,PACRG |
| 2.429e-06 | -12.93 | SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide) | protein interactions | 6634 | 341 | 135 | 19454 | 5460 |
RAB27A,SNIP1,SNRPG,SMN1,MEPCE,HUWE1,SNRNP48,LSM4,TSSC4,CDC40,CD2BP2,TP53,FBP1,UBL4A,NUPR1,ILF2,GEMIN7,PSMB1,PREP,ZBTB2,CDC5L,CWC15,RBM42,MBD5,RPS27L,SPPL3,FZR1,DCUN1D1,CAND1,COPS5,CD81,GTF2E1,HDAC6,RBM17,LSM3,H2AC4,SNRNP70,CRBN,NR1I3,RNF113A,BANF1,PRPF4,BAP1,SLC39A9,DDX46,RPA3,HSPA5,LSM8,FBXW7,CDK7,CFTR,SNRPN,TXNL4A,SF3A1,WDR83,UBE2M,TTI2,HEXIM1,LSM2,METTL14,RPA2,LMNA,ZMAT5,EIF4A3,SF3B6,VIRMA,SMURF1,DNAJC8,NTAQ1,UBE2H,LSM6,RC3H2,GEMIN8,SRSF7,EWSR1,PABPC1,CMTR2,HSPD1,KRAS,DHX38,E2F4,RAF1,SNRPE,SART3,SF3B5,SMNDC1,CHMP4C,LSM10,EZH2,EED,IFIT2,SRSF1,PHB1,FOLR1,DHX15,SNRPA1,LSM5,DDRGK1,HNRNPA1,XPO1,WWP2,PRPF19,MAGOH,DDX23,RAB5A,CRY1,SF3B1,HSPA8,SNRPA,DDX39B,SRSF2,UFL1,WDR77,PIH1D1,EIF4B,PPT1,SNRPD1,SNRPD2,PRMT5,SF3B4,SNRPB2,ESR2,CHCHD3,SNRNP40,LGALS3,SNRPB,PRPF31,BTF3,CFAP20,CUL2,CUL3,MYC,RIT1,ICAM1,BRCA1 |
| 2.442e-06 | -12.92 | NDUFA5 (NADH:ubiquinone oxidoreductase subunit A5) | protein interactions | 4698 | 218 | 93 | 19454 | 5460 |
CYB5A,GATD3,CORO1C,PHB1,RMND1,COX14,NDUFS8,EGLN3,BABAM1,MTRF1,POU5F1,MRPS26,RHOG,HINT2,EWSR1,NDUFA4,HSPD1,NDUFB5,IMMP2L,VDAC1,OTULIN,NDUFA12,NDUFS6,MTG1,CCDC90B,TACO1,VDAC2,LMBR1L,ESR2,MAD2L2,PARL,NDUFAF4,ATP5F1B,BAG3,CCDC85B,PMPCA,CUL3,MTG2,AUH,MYC,HSPA8,EXD2,NGRN,ADRB2,HSCB,TIMM29,DHRS4,ATP5PO,NDUFA1,RAC2,COX4I1,AIFM1,SSBP1,SLC25A12,ATP5PD,PLEKHF2,DPP4,GRSF1,DNAJC4,TMEM70,CHCHD1,ABCE1,CLPB,SFXN1,FASTKD5,DNAJC30,METTL15,AURKAIP1,APOO,MTCH2,MRPL11,SLC25A24,GFM2,NDUFS3,CCNF,UQCRC2,VIRMA,TUFM,NDUFB10,DNAJC19,UBE2H,SQSTM1,GFM1,MAIP1,CRYZ,SLC25A51,PDHB,TTR,CDC42,UQCRC1,TIMMDC1,MTRES1,COX6C |
| 2.449e-06 | -12.92 | TRIM23 (tripartite motif containing 23) | protein interactions | 373 | 356 | 140 | 19454 | 5460 |
EHHADH,RPL27A,TOMM22,LMO3,MORN4,UBAC2,ARCN1,RPS28,ATPAF2,RAMAC,EEF1G,FXR2,UBE2D3,PKP4,LDHB,CUL3,ZNF250,LMO2,PCCB,RBM15B,SNRPB,PRPF31,TSEN54,FAM83A,CCDC25,FHIT,RPS5,HSP90AA1,RAN,CYB5R3,SCNM1,TACO1,HAPLN2,LGALS3,SIAH1,TUBB,TRIM29,SNRPB2,ESR2,ARFGAP1,SPG21,RPL29,ACTN4,FAF2,TUBB4B,RPL18,RNF126,HGS,RPS11,DTWD2,PCNA,ZBTB16,PSMA1,RFC3,ENKD1,RPS27A,RPL28,RPL6,UBE2E2,EIF3D,CASP12,UBE2D1,HSPB1,NAB2,MYEF2,RPL8,TSG101,RPL7,PRPF18,PPIA,UBE2W,RPS14,ZNF326,SNAI2,ACACA,CDR2,MET,TMEM263,HCFC2,SQSTM1,RNF34,PIK3R2,RPL4,UTP23,FAM193B,RPL7A,TNFAIP3,TRIM32,TUFM,ATP5F1A,NTAQ1,TRIM23,LGALS8,UBE2H,CDC73,TMSB4X,RPS3,ALB,UBE2I,TRIM27,CYTH1,TRAF1,EAF2,VIRMA,UBE2L3,CCT5,TP53,TRIM6,CMPK1,TBK1,ZNF581,JOSD1,ZFAND2A,MSRB3,TCEA2,INSM2,PC,RPL3,TRIM63,POLL,HUWE1,PSMA5,RIGI,RPL17,CYTH2,PHF1,USP2,GAPDH,RAB23,RPL24,NXT2,ZNF688,RPS2,SMG9,CXCL14,UBE2N,PSMB1,PPP1R18,SURF6,MDM2 |
| 2.450e-06 | -12.92 | Downstream TCR signaling | REACTOME pathways | R-HSA-202424 | 98 | 53 | 10285 | 3229 |
PRKCQ,PSMD14,UBB,UBA52,PSME1,SKP1,PSMD10,NFKBIA,PSMD7,PSMB10,PSMA5,PTEN,PSMC5,PSMB11,PSMA4,NFKB1,CD247,PSMB3,PSMA2,FBXW11,PSMB6,PSMB1,PIK3R1,CD3G,PSMB7,PIK3R2,PSMD3,PSMC4,PSMB5,PSMA3,PSMA1,PSMC3,PSMD4,RPS27A,PSMB4,TRAF6,PSMD6,PSME2,UBE2D1,IKBKB,SEM1,PSMB9,UBE2V1,PSMA6,PIK3CA,PSMD1,PSMB2,CD4,TAB2,BCL10,PSMC1,UBE2N,PSMD12 |
| 2.479e-06 | -12.91 | Regulation of Hypoxia-inducible Factor (HIF) by oxygen | REACTOME pathways | R-HSA-1234174 | 77 | 44 | 10285 | 3229 |
PSMA4,EPO,PSMB10,EGLN2,PSMA5,PSMB11,PSMC5,PSMB6,PSMA2,PSMB3,PSMB7,PSMD3,PSMB1,PSMA3,PSMB5,PSMC4,PSMD14,ELOC,UBA52,UBB,PSMD10,CUL2,PSME1,PSMD7,EP300,PSMB2,PSMD1,PSMA6,PSMC1,PSMD12,CREBBP,PSMC3,UBE2D3,PSMA1,RPS27A,PSMD4,EGLN3,PSME2,UBE2D1,PSMB4,PSMD6,SEM1,PSMB9,VEGFA |
| 2.479e-06 | -12.91 | Cellular response to hypoxia | REACTOME pathways | R-HSA-2262749 | 77 | 44 | 10285 | 3229 |
PSMB3,PSMB6,PSMA2,PSMA5,PSMB10,EGLN2,PSMB11,PSMC5,PSMA4,EPO,PSMC4,PSMA3,PSMB5,PSMB1,PSMB7,PSMD3,UBB,UBA52,ELOC,PSMD14,EP300,PSMD7,PSME1,PSMD10,CUL2,PSMA6,PSMB2,PSMD1,PSMC1,PSMD12,CREBBP,PSMD4,RPS27A,PSMA1,UBE2D3,PSMC3,VEGFA,SEM1,PSMB9,PSMB4,PSMD6,EGLN3,PSME2,UBE2D1 |
| 2.485e-06 | -12.91 | regulation of cellular response to stress | biological process | GO:0080135 | 521 | 202 | 18204 | 5365 |
THY1,DNAJC2,TFPT,HNRNPK,TLR4,EYA3,INSIG2,KLF4,SLC25A23,PTPN1,WRAP53,PRDX1,CHORDC1,TMEM33,ACKR3,MGMT,DDX5,VPS72,NEO1,SERINC3,TP53,ACTL6B,FADS2,TAF10,MDM2,TAF7,ACTR2,SGTA,NBN,DEK,UFL1,TFIP11,ZNHIT1,PIK3R1,STK24,SLC38A2,SMARCB1,EPO,NFE2L2,CREB3,DUSP10,CCAR2,TBC1D24,FBXW7,SGF29,HDAC6,FCGR2B,TXNDC12,CXCL12,INO80C,TMBIM6,BCL7B,HMGB1,TOP2B,CLU,BFAR,STUB1,DDAH1,RUVBL1,RPS3,RPA2,CRHBP,TAF9,TRIM32,MIR145,MSX1,KMT5B,CERS2,ROCK2,DDRGK1,ACTB,SLC7A11,BCL7C,FUT8,MIR222,CEBPG,DNAJC7,ZNF365,SUPT3H,CGAS,EFHD1,OGG1,H2AX,PML,HAPSTR1,FAM168A,CDK9,PSMD10,CHCHD2,SMARCE1,OPRM1,PELI1,PPP4C,USP15,ENO1,MIR132,DMAP1,VDAC1,ACTL6A,MIF,PPIA,NUPR1,BAX,ERP29,MYC,IGF1R,IER3,EPHA4,PHF13,PTN,MIR96,LPCAT3,MIR21,PPP1R10,ARL6IP5,NACC2,DNAJB6,SEMA4C,AQP11,TAF2,TAF5L,BRCA1,SMARCD3,HSPA5,ZMPSTE24,RUVBL2,RMI2,SUPT7L,ING2,FKBP1B,PMAIP1,CDKN2D,MIR210,PNPLA8,BABAM1,CD36,TPT1,TADA1,MEAF6,EEF1E1,MAD2L2,CAV1,CREBBP,RPL26,INO80E,SELENOS,GREM1,RADX,AGR2,RNF8,DHX9,SPP1,FEM1B,DYRK1A,USP13,UBE2V1,UBE2V2,SPRED2,NCK1,FBLN5,FGF10,GSTP1,SHLD1,PCNA,BAK1,TGFB2,IL1A,SIRT7,KLHL15,BOK,EP300,SVIP,SPRED1,ENY2,PDCD10,UBE2N,DNAJB9,SF3B5,IGBP1,SLC25A14,SNAI2,MIR221,FAS,EIF2AK2,TNR,XBP1,CSNK2A1,TADA3,COPS5,BAD,RGMA,SMCHD1,RNF126,SYVN1,MAP2K1,CRY1,TTI2,NR1H2,KDM1A,MORF4L1,BCL2L1,USP14 |
| 2.492e-06 | -12.90 | cytoplasmic pattern recognition receptor signaling pathway | biological process | GO:0002753 | 69 | 39 | 18204 | 5365 |
OAS1,TRAF3IP3,PHB1,ATAT1,CGAS,KCNJ8,PIK3AP1,LACC1,TNFAIP3,CLPB,MAVS,IKBKB,TLR3,LSM14A,TLR7,TNF,IRF7,NLRP6,TICAM1,RIGI,MAP2K6,NFKBIA,TLR4,PYCARD,TBK1,RNF34,TIFA,IRF3,PHB2,TLR8,BECN1,OTULIN,IRAK4,NLRP3,TRAF6,MYD88,NLRP1,IFIH1,TLR9 |
| 2.493e-06 | -12.90 | EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) | protein interactions | 1965 | 244 | 102 | 19454 | 5460 |
EMC4,HDAC6,CSNK2A1,COPS5,SNRNP70,MAP4,CD274,TMED9,CAND1,RPS16,FZR1,EIF2B2,RPS27L,RBM42,RPL15,DNAJC2,POLR2G,ILF2,VAC14,RNF8,FURIN,NUPR1,SRP72,MAP1B,IGF1R,HUWE1,RPL7A,USP14,AR,EIF3G,CDC73,NRP1,UBE2H,CCNF,PSPC1,EIF2AK2,METAP2,EIF2S2,EEF1E1,CFTR,RPA2,EIF2B3,FGFR1,RPLP0,HEXIM1,PRKCA,HECTD1,RPA3,SOD1,BAP1,SYVN1,MTDH,FBXW7,RPL4,MARS1,WWP2,XPO1,DNTTIP1,CTNNB1,DDRGK1,DDX1,HSPB1,DRG1,PHB1,EZH2,RPN1,CHMP4C,PDHA1,EIF1AX,MOB3C,EWSR1,TRIM11,KRAS,RAD21,MYC,CUL3,SFN,RAB11A,BTF3,BRCA1,HSP90AA1,RIT1,LMBR1L,CMTR1,PRMT5,ANAPC2,MAD2L2,RPL19,ESR2,RPL27A,BET1,NEK7,ETF1,NCOA5,PIH1D1,XRCC5,NMRAL1,TERT,UFL1,EIF1B,STAU1,G3BP2 |
| 2.517e-06 | -12.89 | NR3C2 (nuclear receptor subfamily 3 group C member 2) | protein interactions | 4306 | 41 | 26 | 19454 | 5460 |
PIAS1,PTGES3,FAF1,RABAC1,EP300,UBE3A,PPID,SUMO1,TP53,CAND1,PPP5C,EGLN3,CAV1,VIRMA,AIP,STUB1,PSMC5,UBE2I,TRIM24,FKBP4,DNAJC7,HSP90AA1,CREBBP,YWHAH,PROX1,AR |
| 2.530e-06 | -12.89 | positive regulation of epithelial cell migration | biological process | GO:0010634 | 179 | 82 | 18204 | 5365 |
MIR10B,MIR29A,NUS1,MIR150,PRKCE,VEGFA,BMPR2,MIR210,NRP1,TMSB4X,FGF1,NFE2L2,STAT5A,MIR30A,MIR146A,FGFBP1,MIR21,HBEGF,MIR221,FOXC2,TGFBR2,ARF6,MIR296,SP1,MIR222,RHOJ,SOX9,GLIPR2,AAMP,MIR31,TACR1,MIR342,RTN4,MET,PRKCA,GAB1,HSPB1,MIR143,RAB11A,MIR135B,MMP9,MAP3K3,ATP5F1B,MIR126,FGF10,CALR,ROCK2,IFNG,MIR101-1,TGFB2,MAP2K3,MIR200A,ARHGAP5,FOXP1,VEGFC,RHOB,ITGA2,GFUS,EMC10,PROX1,MIR939,PLG,PIK3CG,MIR23A,IQSEC1,HDAC6,MIR10A,SEMA5A,FUT1,CD40,ANGPT1,AKT1,MIR132,AKT3,SRC,ATP5F1A,WNT7A,FGF16,FGFR1,FGF7,HMGB1,MAPRE2 |
| 2.544e-06 | -12.88 | Regulation of mRNA stability by proteins that bind AU-rich elements | REACTOME pathways | R-HSA-450531 | 91 | 50 | 10285 | 3229 |
PSMB11,PSMC5,PSMA5,PSMB10,PSMA4,HNRNPD,EXOSC8,ANP32A,PSMB3,PABPC1,PSMB6,PSMA2,PSMB1,EXOSC4,PSMD3,PSMB7,PSMC4,PSMB5,PSMA3,YWHAB,PSMD14,UBB,UBA52,PRKCA,HSPA8,PSME1,PSMD10,EXOSC1,YWHAZ,PSMD7,DCP2,HSPB1,AKT1,XPO1,PSMA6,PSMD1,PSMB2,PSMD12,PSMC1,TNFSF13,PSMA1,PSMC3,PSMD4,RPS27A,PSMD6,PSMB4,PSME2,EXOSC3,PSMB9,SEM1 |
| 2.550e-06 | -12.88 | protein targeting to mitochondrion | biological process | GO:0006626 | 62 | 36 | 18204 | 5365 |
TOMM40L,TOMM40,TOMM6,TIMM13,TIMM8B,DNAJC19,TOMM20,IMMP2L,ROMO1,TIMM23,SAMM50,FBXO7,GRPEL2,CHCHD4,PMPCA,TIMM29,TOMM70,TIMM21,FIS1,TRMT10B,HSP90AA1,TOMM7,TIMM10,TIMM17A,GRPEL1,MTCH2,MTX2,TSPO,MGARP,TOMM22,AGK,AIFM1,HSPD1,DNLZ,AIP,TIMM8A |
| 2.696e-06 | -12.82 | HEY1 (hes related family bHLH transcription factor with YRPW motif 1) | protein interactions | 23462 | 140 | 65 | 19454 | 5460 |
RPL23,HNRNPD,SMAD9,IQSEC1,HNRNPA1,CSNK2A1,TLE1,HSP90AB1,MDM2,SNRPD3,DERL2,RPS10,RPS16,TNKS,ACTA2,RPL9,SMAD3,RPL12,RPL8,RBPJ,TENT5D,TUBB4B,RPS7,RPL15,TUBA1A,CCT5,TP53,FEN1,HNRNPK,EWSR1,CCT8,HNRNPA2B1,RAB1A,RPS5,NTRK3,NONO,SNRPB,RPS29,RPS17,STK38L,ACTB,TUBB,RPS20,SNRPD1,HEY2,CSNK2B,TUBA1B,TMA7,RPS3,FAU,HECTD1,PCLAF,CREBZF,CDK7,SNRNP27,RPS14,SKP1,HSPA5,STK38,YTHDF1,FBXW7,DDX5,HSPA8,SYVN1,DDX46 |
| 2.699e-06 | -12.82 | GTF2F1 (general transcription factor IIF subunit 1) | protein interactions | 2962 | 207 | 89 | 19454 | 5460 |
RPL31,S100B,RPS24,BAG2,H3C1,KRAS,GNL1,KPNA2,ASF1A,MEPCE,PRPS1,RFC2,TP53,LBH,JUN,GTF2E2,MSX2,CDK8,POLR2G,POLR2C,SMARCB1,POLR2D,PSMC3,CCDC71,EEF1B2,GTF2B,FEZ1,PLPPR1,RPL35A,CDK9,WIF1,TAF7,ERCC3,GTF2E1,CSNK2A1,XPO1,HNRNPA1,DDRGK1,DEGS1,DDX23,MED21,MED4,RPA3,SNRPA,FOS,TCEA1,PTN,PSENEN,EEF1G,FBXW7,STK38,COIL,GTF2H4,WDR77,SF3A1,SNRNP27,CCNH,PRMT2,CFTR,RPA2,CTDSP1,KCTD12,GTF2H5,ZNF330,PRMT5,TRIM27,GTF2A1,GTF2H2,POLR2F,GTF2F2,DAPK1,TUBB,SNRNP40,SPCS1,POLR2B,MAD2L1,TAF11,APEX1,TCEAL7,MYC,CREBBP,STAC3,IRF1,DRAP1,AR,CIRBP,BRCA1,CDC73,UBE2H |
| 2.699e-06 | -12.82 | NOL6 (nucleolar protein 6) | protein interactions | 65083 | 207 | 89 | 19454 | 5460 |
G3BP1,KRAS,MIR155,RPS4X,RPL31,EZH2,RAF1,KIAA0408,RPS7,NOP58,MIR9-1,DHX15,MIR7-2,EED,MIR214,MIR221,MIR1-1,MIR140,IFI16,MIR143,ATG7,MIR29C,G3BP2,TANK,RND2,SNRNP40,SIAH1,MIRLET7D,RPL10,MIRLET7B,RHOB,MIR363,RPS5,RIT1,MYC,MIR98,H3C1,MIRLET7C,MIR16-2,MIR20A,MIR17,HBP1,MIR200C,MIR15A,IKZF5,RPL15,SPPL3,MIRLET7G,MIR429,SURF6,NAP1L5,MIR106B,RAC2,MIR25,MPHOSPH10,MIR34A,BRD3,MOV10,RPL4,MIR7-3,MIR107,MIR29A,AATF,MIR10B,RHOU,RPA3,NLE1,MIR205,SIRT7,MIRLET7I,EXOSC4,MIR34C,RPA2,LMNA,MIR21,MIR7-1,MIR34B,CDC42,MIR1-2,SMURF1,RPS3,CCNF,POP7,FGFBP1,UBE2I,MECP2,RRP7A,UBE2H,RPL7A |
| 2.700e-06 | -12.82 | GABARAPL2 (GABA type A receptor associated protein like 2) | protein interactions | 11345 | 162 | 73 | 19454 | 5460 |
NPSR1,AK2,RB1CC1,RPS2,HNRNPD,PRDX1,TBC1D5,INSYN1,ATG7,TP53INP1,HYPK,CPNE1,ZBTB2,HSP90AB1,HACD3,TSR2,TRIM45,CLN8,BRD9,NUDT19,AAMP,MSRB3,MRPL49,RAP1A,TP53,IRGQ,STBD1,ARFGAP1,VDR,AZI2,GLRX5,GABARAPL1,MAP1LC3B,ATG4A,VDAC1,GUK1,RETREG1,NEK9,TRIM21,ATG3,YWHAZ,CCT2,FXN,HSP90AA1,TBC1D25,CUL3,TRIM32,ISCA2,AK3,TXNDC12,DYNLL1,TAX1BP1,TXN,KBTBD6,GPR37,OPTN,MCPH1,SGTA,KIAA1958,RETREG3,TP53INP2,AGTRAP,SEC62,FUNDC1,GOSR1,BNIP3L,GABARAP,MEF2A,TEX264,TMEM160,HADHA,SQSTM1,RAP2A |
| 2.703e-06 | -12.82 | protein-macromolecule adaptor activity | molecular function | GO:0030674 | 989 | 361 | 18094 | 5411 |
KLHL22,TADA3,MED9,VPS18,USE1,MDC1,STX5,CNOT2,RUVBL1,GNB1,RUVBL2,MED11,TICAM2,TRIM5,DHRS7B,FBXW7,MED17,ZNF451,CTBP1,PIAS1,RETREG1,LMO2,FEM1C,EDF1,SH3BGRL,TAF9,MED4,CRADD,HOMER1,STX17,GAS2,HDAC3,STX12,TRIM24,APEX1,SLA2,RXRG,ING2,AP1G2,KDM2A,HYAL2,APH1A,WDR77,NFKB1,TRIM32,TRIM27,NAB1,SEC22B,STUB1,ENO1,BTG2,GOSR1,SUPT7L,YKT6,PFDN5,CGAS,BUD31,HNRNPC,TRIM6,BFAR,BCL10,YTHDF1,ACSS2,DNAJC2,MED27,FAF2,CAV2,ZBED1,MED21,HCFC2,KLHL3,THAP7,SS18,GNB3,HRAS,NBN,PHF12,CITED1,TAF11,CCAR1,BIRC2,WBP2,SRSF2,PRMT5,NLRP1,COPS2,HPF1,TRAF2,STX6,SAP30,CSNK2B,USP15,SNAP23,AP2M1,MED29,FEM1A,KDM1A,YAF2,SNAP25,CD3G,EID1,NOS1AP,RERE,USP16,C1D,BRCA1,FBXL19,MTA3,SSBP3,DMAP1,MYD88,VAMP2,KRAS,HAX1,NDC80,CRKL,TRIM21,GMNN,ARF6,DHX9,HSBP1,SETD3,PHF13,CAV1,CBFB,ACTL6B,GRB10,MED10,HCLS1,LAMTOR1,DYRK1B,SMARCE1,RETREG3,STX8,JADE1,STX11,AP2S1,RACGAP1,NAPA,TLE1,SPATA2,MAVS,IRF4,GOSR2,MED30,CUL3,FZR1,BET1L,MTDH,MED23,ELOC,EZH1,DDX1,AP2A1,RBFOX2,CNOT6,ROPN1B,YTHDF2,APPBP2,ENY2,RAP2C,FLRT3,PIR,JUP,PIK3R1,PHB1,SARM1,FRS3,HSPA8,TADA1,NFE2L2,SUB1,PRKCB,BET1,UBE3A,RETREG2,NUPR1,FBXO42,DUSP19,NAPG,TAX1BP1,SMARCD3,SEC22A,HIRA,FBXW11,SDCBP,TAF5L,OPTN,STX10,PTPN11,DDX4,TCAP,KLHL25,KLF4,LGALS3,AP1S2,PRMT2,FLRT2,LDB1,SDR16C5,NR0B1,TRIM52,ZMYND11,CREBBP,SETD5,CCND1,G3BP2,STAP1,CUL2,FOXP3,HR,EID2B,MTA2,VAMP1,DGCR8,TRIP4,MECP2,SUFU,ELK1,DET1,IRF2BP1,ATG16L1,SHC1,STX7,HNRNPA2B1,MAP2K1,FHL3,TSG101,BEND6,NCSTN,SAP18,RNF14,NEFL,KCTD17,CD274,TRIM37,TGFB1I1,SMARCB1,MED22,BICD2,TRIM8,MED31,IFNAR1,PEX26,GAB1,RIOX2,ALKBH5,NUCKS1,PRNP,JCHAIN,ACTN4,NLRP6,G3BP1,NCK1,RBBP8,SUPT3H,ATP1B3,VAMP7,CBX5,RNF20,PIH1D1,NUP62,LPXN,SQSTM1,COPS5,IRAK1BP1,EP300,ST13,SERTAD2,COL1A2,IDE,LMO3,SNAP29,TIRAP,DVL2,LMO4,KGD4,TCOF1,PCMTD1,HMGA1,SPSB1,SOCS2,CSTPP1,SKP1,NAB2,SAP30L,DDIT3,LDB2,PCBD1,DYRK1A,VGLL2,BRD3,ACTL6A,SIN3A,RLIM,PEX3,STX18,TICAM1,NHERF1,IGF2BP1,RRAGA,PRPF31,HMGB1,TRIM22,VAMP3,ARL2BP,ATP1B1,BTG1,FBXO9,ALYREF,UBE2L3,CTNNB1,NCOA5,VAMP8,ERG28,VTI1B,SIAH2,SETD4,BECN1,SERINC1,DTL,EID2,CDC42SE2,KLHL15,TRIM62,TRIM11,DNAJB2,FEM1B,STX1A,GNB4,TRIM15,PML,NUP153,PQBP1,FKBP4,CRYM,THRAP3,BCL9,MED13L,EWSR1,STX16,NLRP3,TOPBP1,RB1,AP1M1,CNOT7,CDC20,NFKBIB,AR,FBXO3,GFI1,RAB3A,PSMD10,NIBAN2,MIDEAS,TOB2,AIP,EZH2,SURF6,FBXO7,NME2 |
| 2.736e-06 | -12.81 | RRP15 (ribosomal RNA processing 15 homolog) | protein interactions | 51018 | 151 | 69 | 19454 | 5460 |
RPS24,RPL3,EWSR1,PPAN,RPL31,MAP1B,SRSF4,RPL28,THRAP3,PAK1IP1,KRAS,SOX2,JUN,AURKAIP1,TAF1D,E2F4,RAF1,SART3,CHMP4C,CLN8,MRTO4,KRR1,SRSF1,SYNCRIP,SURF6,CDK9,LYAR,RPS10,DDRGK1,CSNK2A1,COPS5,FAM133B,USP2,IFI16,GRSF1,DRG1,CHCHD1,SNRNP70,DDX23,RNF113A,NLE1,RPL4,NPM3,DGCR8,KLF12,SYK,HEXIM1,RPLP0,RPS9,PRKRA,FGFBP1,CSNK2B,EIF2AK2,NOPCHAP1,ESR2,SRPK2,RPL10,APEX1,SMURF1,CAVIN2,USP14,PPP1CC,RPL7A,CUL3,RPF2,MYC,UBE2H,H1-1,MAPRE1 |
| 2.736e-06 | -12.81 | NFE2L2 (NFE2 like bZIP transcription factor 2) | protein interactions | 4780 | 151 | 69 | 19454 | 5460 |
H3C1,BACH1,KPNA2,NFE2,ATF3,ENC1,TP53,DUSP1,JUN,SMAD1,ELF1,SUMO2,ELK1,TEF,ETV6,DFFA,MAP2K6,CEBPG,FOSL2,DCAF11,HNRNPD,NQO1,UBE2E2,CREBL2,SIAH2,UCHL3,KDM1A,CERS2,HDAC3,SYVN1,DDIT3,TRIM22,ARPC2,SQSTM1,EP300,LMNA,PPARG,MAP2K1,PRKCA,ELF5,PAQR3,SUMO1,CDKN1A,CREBZF,MAFG,EIF3J,ACTB,TUBB,PAQR4,APEX1,OPTN,IRF2,TRIM24,EIF3G,FBXW11,BRCA1,UBE2E3,ATRAID,HSP90AA1,RIT1,CREBBP,MYC,AKT1,CREB3,COPS7A,CUL3,ATF4,IRF1,H2BC9 |
| 2.744e-06 | -12.81 | KPNB1 (karyopherin subunit beta 1) | protein interactions | 3837 | 512 | 191 | 19454 | 5460 |
VDAC1,RUVBL1,NUP42,KRAS,RUVBL2,TAF10,MTA2,SMARCB1,SMNDC1,PDHA1,TUBB4B,GLE1,TNPO2,NUP37,TUBA1A,SNAPIN,RANBP1,MAX,HMG20A,EED,POU5F1,MGMT,AGR2,CTNNB1,DDRGK1,NT5C2,XPO1,EEF1G,STAU1,ADRB2,UFL1,ARRDC3,EP300,HSPA8,HDAC5,LCA5,PIH1D1,CSNK1A1,PPT1,MAP2K1,ZC3H14,NUP62,ESR2,CAVIN2,GTF2F1,DLST,LMBR1L,H1-10,BTF3,PAPOLA,HNRNPC,RUSC2,MYC,MEPCE,KPNA2,CSE1L,NUP107,NOSIP,MAP1B,IPO8,TP53,UBL4A,CDC5L,CAND1,FZR1,CD4,CD274,KPNA1,SMAD4,PPM1D,COPS5,CSNK2A1,SELENOS,HSPA5,RNF113A,DERL1,TRIM3,BAP1,HEXIM1,UBE2M,FGFR1,RPA2,RPRD1B,CFTR,IGFBP3,POLR1D,SUMO1,NOPCHAP1,DYRK1A,SMURF1,KCTD9,BUB3,PHAX,PSPC1,UBE2H,BICD2,SPOP,CCNB1,MORF4L1,SLC25A1,RAD21,GNL1,G3BP1,CHMP4C,EZH2,PLEKHA8,NUP153,B3GNT2,NUP35,EGLN3,NOP58,HP1BP3,COPS2,PHB1,THOC2,AHSA1,MAP3K14,ZNF207,DYRK1B,PTN,NUP50,HADHA,CRY1,PRKD3,ETF1,PPP1CB,H2BW1,JAK2,TAF11,RPL35,LGALS3,RANBP6,POLR2F,RAN,BAD,ILK,RIT1,BRCA1,LMNB1,FAS,SAMHD1,SMARCE1,CUL3,CUL2,NFYA,MDC1,SMN1,RIGI,THRAP3,HUWE1,HSD17B10,HAPSTR1,FAF1,SOX9,LBR,ING1,COMTD1,ZBTB2,CDK9,PRNP,SMAD3,CTDSPL2,CRBN,TMEM209,FBXW7,CERS2,B2M,SQSTM1,SYVN1,SIRT7,RPA3,PPM1G,SOD1,RPL26L1,STOM,GRM2,LMNA,ATG16L1,VIRMA,NDN,UBE2I,PTEN,ZBTB18,CCNF,MAPRE1,SMAD2,TXNIP,PPP1CC,KPNA6,PTHLH,RALB |
| 2.807e-06 | -12.78 | MCM5 (minichromosome maintenance complex component 5) | protein interactions | 4174 | 402 | 155 | 19454 | 5460 |
PHB1,S100A8,MAGED2,SPTAN1,SRSF10,EGLN3,CEP19,HSP90AB1,LANCL1,DHX15,KIAA0232,PRDX1,MDFI,YWHAG,HNRNPA1,CTNNB1,DDRGK1,H2BC17,DICER1,PPP3CA,SLC25A5,NEK9,HNRNPA2B1,RABGGTB,G3BP1,KRAS,MCM6,RPS27A,SSRP1,RAF1,TOP3B,H1-3,KIF2A,EZH2,TUBB4B,H2BC1,PDHA1,MOB3C,NFKBIA,PRMT5,CDC7,MCPH1,MATR3,PSMD4,STAT1,TUBB,ESR2,MYC,CUL3,HNRNPC,MCM4,BAG3,MCM3,MCM8,H2AZ2,LMNB1,BRCA1,HSP90AA1,COP1,RIT1,H1-1,HSPA8,SF3B1,HDAC5,EP300,DDX5,PSMA3,UFL1,STAU1,MCMBP,PHB2,PYGB,POLA2,AZGP1,RRAGA,NUDT3,H2AC1,EIF4B,PIH1D1,H2AZ1,SYNCRIP,FZR1,TOP1,TMPO,CDC5L,ORC5,H2AC14,GPRASP2,HDAC6,CD81,API5,GAPDH,H2AC4,USP15,FAF1,H2AC25,NAE1,IFT52,DHX9,HSD17B10,CAMK2G,H3C1,THRAP3,H2BC14,H2AC6,H2AJ,TP53,EEF1A1,H2AX,GINS4,MINDY3,ILF2,NUPR1,CCNF,PELP1,ENO1,CALML5,PTEN,PYGM,NDN,RALA,COPE,UBB,VIRMA,CIAO1,ATP5F1A,H2BC9,CFL2,CFL1,FBXO7,AR,ZBTB38,UBE2H,ORC6,RPA3,SOD1,RHOU,BAP1,DVL2,SIRT7,H2BC12,TCEA1,PDHB,SF3A1,SPTBN1,ATG16L1,UBA52,RPA2,JUP,LMNA,H2BC11,H2AC7,GRM2,HEXIM1,UBE2M |
| 2.809e-06 | -12.78 | RHO | prosite domains | PS51420 | 37 | 24 | 12186 | 3388 |
RHOBTB1,RHOH,RND3,RAB6A,RAB37,RAB29,RHEB,RAB13,RAP1A,RHOJ,RAB3D,RHOG,RHOB,RAC2,RND2,RHOU,KRAS,MRAS,RAB3A,RAB30,RAB1A,RAB27A,CDC42,HRAS |
| 2.824e-06 | -12.78 | KPNA3 (karyopherin subunit alpha 3) | protein interactions | 3839 | 233 | 98 | 19454 | 5460 |
FAM50B,NUP50,HADHA,EEF1G,FTL,COIL,IER2,GTF2IRD1,NFKBIA,RAN,NFKBIB,RBBP4,SNRNP40,CAVIN2,ESR2,APEX1,MAT2B,POLR2B,CBX5,CUL3,HNRNPC,GRB10,MYC,MCM4,BRCA1,DCAF4,FAS,COP1,GNL1,POLDIP3,GTF3C3,MCM6,MED9,RANBP1,RAF1,NUP153,EZH2,RPS23,OTULIN,RPRD1A,COPS2,DYNC1I2,EGLN3,WWP2,ZCCHC10,HMGA1,NT5C2,HSPB1,CDKN1B,RPA3,BAP1,SQSTM1,FBXW7,NPM3,B2M,ATG16L1,HSP90B1,ZNF326,LMNA,RPA2,ACACA,NOL7,RPL26L1,UBE2M,TUBA1B,CCNF,MACROH2A1,PHAX,HEXIM2,KPNA6,ZCCHC12,ATOSB,MECP2,BAHD1,MAPRE1,EPHA2,MAP1B,KPNA2,THRAP3,TSSC4,HUWE1,MEPCE,IPO8,ACTR1A,MAP1LC3B,NFE2L2,NUPR1,SPMIP9,CTDSPL2,RB1,LDLR,FZR1,NCBP2,NFKB1,ERCC3,PPM1D,BRD3,KPNA1 |
| 2.824e-06 | -12.78 | GLUD1 (glutamate dehydrogenase 1) | protein interactions | 2746 | 233 | 98 | 19454 | 5460 |
FASTKD5,PSMB10,IGF1R,HSD17B10,SFXN1,MAP1B,GFM2,DNAJC2,DDX42,AURKAIP1,MRPL11,RPSA,KBTBD4,TMPO,EPHB6,PRNP,ARF6,COX4I1,AIFM1,CD274,SSBP1,TESK1,TIAM1,TMEM70,CRBN,KLHL22,PPIL4,ENY2,GRSF1,RPL4,GFM1,THUMPD1,BAP1,RPA3,MTRES1,PARD6A,MET,E2F6,PTPN22,METTL14,RPA2,PPP1R10,STAT5A,NDN,GSK3A,CTTN,METAP2,PSPC1,UBE2H,OAT,RC3H2,TUFM,FLOT1,G3BP1,DCP2,COX8A,CDK5,EWSR1,HINT2,HSPD1,RND3,PDHA1,RAB4A,RAF1,NUP35,RMND1,HYPK,GATD3,PHB1,DRG1,HSPB1,PEX3,POU5F1,RHOG,MTRF1,G3BP2,HSCB,AKAP1,HDAC5,HSPA8,EXD2,EMC9,MED23,KLF3,SEC62,BET1,RPL19,DYNLL1,CCDC90B,TACO1,ILK,SP1,NTRK3,CUL3,PMPCA,TXNRD2,AUH,MTG2 |
| 2.832e-06 | -12.77 | SAR1A (secretion associated Ras related GTPase 1A) | protein interactions | 56681 | 318 | 127 | 19454 | 5460 |
EEF1AKMT3,SRPRA,SEC23A,FA2H,LDLR,CAND1,VTI1B,CAV1,AIG1,TMPO,CNIH1,MOV10,CD81,TMEM107,TRAPPC2L,SLC35A1,TMEM42,ADGRE2,CLEC7A,STX8,PC,DHX9,UNC50,ERG28,RPL3,RPL17,PSEN1,SELENOK,NRM,UBIAD1,LBR,TRAPPC13,FRRS1,RPS3,OPTN,VAMP3,PTEN,SYNGR1,B4GALT1,VIRMA,TECR,GJB2,SEC13,VAMP5,RAB2A,GORASP2,HMOX2,ANO3,CHRAC1,IGF2BP1,TMEM263,ORMDL1,SLC39A9,RPA3,TMEM243,RAB9A,DERL1,MAVS,MTDH,TMEM254,LSM12,RPL4,FUT8,TRAM1L1,SEC22B,ST7,CFTR,CDC42,PLP2,GRM2,GOLGA5,STOM,RPA2,LEMD3,ACACA,TMEM14A,RPL9,RPL8,STX5,TRAPPC10,RAB1B,HSP90AB1,TMEM97,MARCHF5,SLC38A7,PMP22,HMBS,AGR2,HNRNPD,TMT1A,TMEM147,SLC39A3,SLC39A7,ACVR1B,TRIM37,KRAS,ARL5B,SAR1B,TFG,RPL28,TPD52,LGR4,EEF2,AQP3,CTSA,STIM1,ARF1,SEC61B,TENT5C,RPL35,SLC30A5,BTF3,PLN,SCFD1,JAGN1,PEBP1,EMP3,EP300,AKAP1,HSCB,GOSR1,STX7,BET1,SEC22A,OTULINL,YIPF5,FAM3C |
| 2.833e-06 | -12.77 | IPO5 (importin 5) | protein interactions | 3843 | 396 | 153 | 19454 | 5460 |
KPNA6,GPRASP3,UBE2H,ATP1A1,NRP1,NAPA,MSN,PTEN,RPS20,SEC61A1,PSMC5,CAB39,ZNF330,CCNF,PELP1,UQCRC2,VIRMA,ADRM1,KCTD9,NDN,GABARAPL2,CFTR,CDK7,POLR1D,CDC42,ATG16L1,NOL7,UBE2M,RNF146,PPIH,SQSTM1,SYVN1,IRF3,NBN,SIRT7,PML,RPA3,BAP1,RHOU,GABARAP,HSPA5,MRPL20,FAM20C,DPP4,TSNAX,MAP4,KPNA1,CHCHD1,H2AC4,PSMD7,LDLR,PREP,CD274,PTPN1,CDC5L,PRNP,CAND1,FZR1,SMAD1,ZMYM3,MAP1LC3B,TAF1D,SRFBP1,FURIN,LLPH,RPL23A,HAPSTR1,PSME1,NOSIP,FAF1,CAPZA1,MEPCE,CSE1L,WASL,NOC4L,H3C1,HUWE1,SFN,CUL3,NOP16,CUL2,NFYA,MYC,LSM14B,TNFAIP8,DCAF4,BRCA1,FAS,RAN,AVPI1,PSMB6,RPL35,LGALS3,PSMD6,RANBP6,DET1,PPP1CB,RPL27A,NUP62,CNDP2,PIH1D1,EIF4B,HEXB,ARMCX3,EP300,AKAP1,EMG1,MRPL34,LCA5,MACIR,COIL,STAU1,MCMBP,MAP3K14,DDRGK1,XPO1,WWP2,PSMD3,RPL23,YWHAB,CBL,PSMD10,AGR2,MAP1LC3A,MAGED2,DHX15,DIRAS3,EGLN3,SUMO2,RPL7,DYNC1I2,RBIS,RPS7,SOX2,GABARAPL1,PPP2R1A,RPL29,NUP153,RANBP1,TXNRD1,TOP3B,B3GNT2,MOB3C,BZW2,EZH2,PLS3,RPN1,CCT8,PABPC1,RPL31,PSMD12,HNRNPF,KRAS |
| 2.834e-06 | -12.77 | ARF6 (ADP ribosylation factor 6) | protein interactions | 382 | 568 | 209 | 19454 | 5460 |
SNX1,SNX2,TMEM237,WDR6,GJA1,PDCD1,RHOG,SLC20A1,LRRC57,PIK3R1,WDR11,SEMA4C,GPAA1,PLCB1,STIM1,EZH2,VAMP2,RPN1,STX12,ITGB5,RAF1,MARCKSL1,TULP3,FAF2,NDUFAF4,ARF1,FAM91A1,RHOB,MYO6,RIT1,SLC7A11,RAB11A,PKP4,NIBAN2,VEZT,RP2,STX7,UPF3B,CLDN1,VAPB,SLC25A3,ARCN1,NOTCH2,PGRMC1,TOR1AIP2,EHD1,ALCAM,CAV1,PTPN1,SRPRA,CDCA3,MSMB,TIAM1,ESYT1,SLC2A1,OSBPL8,RELL1,TMEM199,RAB23,LAMP3,SNAP91,CTNND1,ARF4,DLG1,SFXN1,RAB1A,SNAP23,SEPTIN7,KRIT1,ZDHHC8,FBXO8,CASK,CCDC47,LBR,SLC29A1,SNX3,YES1,F11R,RAB14,SEC63,TECR,SH3BP4,FERMT2,VAMP3,STUB1,WDR45,AP2A1,EPHA2,FLRT3,DHPS,HMOX2,RACGAP1,DEPDC1B,PIK3R2,YKT6,SLC7A1,ATG4C,TMEM209,CDC42EP4,RPA3,ITGA2,STOM,PICALM,GOLGA5,SLC12A2,JUP,CDK1,AGAP1,UBA52,CCND1,PIP5K1A,SEC22B,ARHGAP1,CNP,ASIC1,RAB1B,VAMP7,RAB35,TNIK,C2CD4C,STX5,FKBP4,RAB5C,LAMP2,IQSEC1,PPFIBP1,SLC20A2,ROCK2,KRAS,RAB8B,VAMP8,TMEM87A,RUVBL2,EFNB1,GNAQ,ARFGEF1,HTR2A,RPS7,TUBA1A,RPL10,ATP6AP2,ACAP2,FAM83B,LAMTOR1,THTPA,SLC38A1,TBCE,SLC1A3,STAU1,PHB2,ABCC5,MT2A,AKAP1,YAF2,UBAC2,BET1,USP6NL,FCHO2,ARL6IP5,ILVBL,LMAN1,TMPO,SLC38A2,CAMLG,ITGA6,ARL4D,RAP1B,ADD1,SLC39A10,TUBG1,AGPAT1,DPP4,AKAP12,FKBP8,CYTH2,MEPCE,SLC6A8,ATP2B4,PALM2AKAP2,SLC16A1,TFRC,NUPR1,GNAI3,CHRM3,SNAP29,UBIAD1,RALA,SRC,ROCK1,NECTIN2,CDIPT,UQCRC2,CYTH1,AP3S2,SNX5,ATP1A1,RAB2A,NDUFAF2,GORASP2,ARHGAP21,EXOC5,FTSJ1,ARFIP1,RPA2,LEMD3,CSNK1G3,CAPN1,SPTBN1,SNRNP27 |
| 2.848e-06 | -12.77 | SMAD4 (SMAD family member 4) | protein interactions | 4089 | 503 | 188 | 19454 | 5460 |
CTNNB1,TENM3,DDRGK1,BTF3L4,PPFIBP1,XPO1,SMAD9,PTK7,CHMP2A,HMG20A,PAIP1,TTC9C,ISG15,NCSTN,ARFGEF1,MAX,HGS,DLX1,EWSR1,PAX6,RPL28,ROCK2,CREBBP,RRAS2,DKK3,ZMYM2,ZNF189,ESR2,APEX1,GPNMB,STAT2,CD59,SHMT1,CNDP2,EP300,STK26,DDX39B,COPS5,DNAJB2,CMSS1,USP15,SMG8,SNRNP70,SHC1,SMAD4,RAC2,PREP,ALYREF,METAP1,ITGA6,ITK,FZR1,PLG,PPP3R2,ACADSB,DNAJC2,NHERF1,GPD2,NKX3-2,RAB13,SNIP1,PCYOX1L,METTL18,TGFBR2,RAB3B,PDE12,AKT1,SORD,SNX5,ACOX1,SUCLG2,ROCK1,SMURF1,RALA,HYAL2,SUMO1,SPTBN1,WWP1,STX17,QRSL1,ARFIP1,IRF3,HSPA5,TICAM2,KDM1A,MMUT,MAP1S,TST,TRAF6,MRPL18,CDK5RAP3,RHOG,SASH3,XPO5,PPP2CB,THOC2,KIF3B,JUN,E2F4,TXNRD1,NLRP2,CYB5B,EZH2,UBE3A,FHL3,HECTD3,SYPL1,THNSL1,RPS27A,GNL1,ACVR1B,ARL5B,LAMB2,CAPG,RIOK2,USP13,SP1,BAX,EXOC8,BRCA1,LMO4,CDKN1A,EHD1,RASL12,CRYAB,MED23,RMND5B,DNAJC3,FBXO30,TGFB1I1,RNF11,CYFIP2,HDAC6,NFKB1,FBXO34,EXOC2,TCTA,SMAD3,ALDH1A3,HRAS,TFE3,CITED1,CDK9,PRNP,MRPL50,SMAD1,EEF1A1,GBE1,PDE6D,SERPINA1,MLLT11,PPP1R12A,ABHD10,CSH1,CAMK2G,AR,HSPA14,HERC4,SMAD2,STK24,UBE2I,GNPDA1,EIF4A3,CCNF,STUB1,JUNB,SMAD5,UBE2L3,UBB,SFRP4,CPT2,RHOJ,EIF3J,UBLCP1,EID2,CRAT,UBA52,SPR,FBP2,SQSTM1,INPPL1,RPA3,DAD1,MEF2A,PIAS1,PFKFB2,PIK3R2,IRF7 |
| 2.872e-06 | -12.76 | EIF5B (eukaryotic translation initiation factor 5B) | protein interactions | 9669 | 165 | 74 | 19454 | 5460 |
PHB1,UBE2N,DKC1,CAND1,FZR1,DDRGK1,ZNF207,HDAC6,XPO1,CSNK2A1,WWP2,PDIA3,BRD3,POU5F1,CBL,SNRNP70,AGR2,DEGS1,HAPSTR1,CDK5,CDC42SE1,UBE2A,SRSF12,GNL1,TSSC4,KRAS,GTF2E2,LGR4,SOX2,E2F4,TP53,SUPT5H,FBP1,B3GNT2,NUPR1,OTULIN,RNF8,EIF1AX,DNAJC2,TFCP2,CMTR1,SNRPB2,RHOJ,USP14,SFN,CUL3,MYC,UBE2H,MAPRE1,ZBTB38,BRCA1,FTSJ3,RC3H2,SPOP,PMAIP1,RNF113A,SQSTM1,HSPA8,SIRT7,RPA3,BAP1,NHP2,FBXW7,STAU1,NOP53,UFL1,EIF5B,MRPL12,CDC42,PIH1D1,RPLP0,ZNF574,IDH2,RPA2 |
| 2.884e-06 | -12.76 | CDKN2A (cyclin dependent kinase inhibitor 2A) | protein interactions | 1029 | 330 | 131 | 19454 | 5460 |
EXOC2,BECN1,TDRD7,TUBG1,GAPDH,E4F1,COPS5,MOV10,CDC5L,PTP4A3,MYL12A,MDM2,TOP1,FZR1,NAT2,RAC2,CDK6,HRAS,PSMC3,ING1,CDK4,TP53,EGR1,PSEN1,BACH1,HUWE1,SERTAD1,IGF1R,GALNT12,CDKN2AIP,CASC3,UBE2H,ZBTB38,STK11,EPHA2,AR,PPP1CC,GMNN,ANAPC15,SUB1,ZNF687,AKT1,NMI,SRPK2,SFRP4,RHOJ,ZBTB17,PTEN,UBE2I,OPTN,CCNF,PRKCA,TMOD1,METTL14,GRM2,LMNA,CDC42,TPT1,CCND1,LSM8,DGCR8,IRF7,MIS12,PML,ARHGEF6,BAP1,YWHAB,BCL2L1,PEX3,RHOG,AK2,CDK5RAP3,IKBKB,YWHAG,YWHAH,DYRK1B,SIVA1,ANKRA2,HSP90AB1,EGLN3,RHOH,AZIN1,ARHGAP25,FOLR1,RHOBTB1,TUBB4B,RPS7,EEF2,MAPK10,ISG15,ACTN4,TUBA1A,RAF1,MCM6,UBE2A,FKBP2,PCNA,RUVBL2,CDKN2C,ARGLU1,HNRNPA2B1,MAF1,SP1,HSP90AA1,BRCA1,RHOB,SNRPB,CDKN2D,HNRNPC,CUL2,CUL3,MYC,NCKAP1,ACTB,TUBB,SEC61B,CDC7,UBE2S,RSRC1,LMBR1L,MAP2K1,VAMP1,RND2,PPP1CB,NOP53,SOX3,TERT,RAB5A,EP300,HSPA8,SNRPA |
| 2.897e-06 | -12.75 | SAFB (scaffold attachment factor B) | protein interactions | 6294 | 236 | 99 | 19454 | 5460 |
HDAC3,HMGB1,PIAS1,RPA3,PML,CLK1,CDK1,RPA2,ATG16L1,CAPN1,SRPK2,SF3B6,ACAT1,PEA15,ELAVL2,NRP1,UBE2H,GGCX,ANAPC15,ERLEC1,HNRNPK,SEPTIN7,RPL23A,ABCE1,TFRC,SURF4,NUPR1,FURIN,FBP1,TP53,MAP1LC3B,APOBEC3D,SPPL3,TOP1,CDK9,ZBTB2,LDLR,SNRNP70,TMOD2,DPP4,CSNK2A1,TRA2B,EEF1G,STAU1,SAP18,SNRPA,XRCC5,HSPA8,EP300,USP39,TRMT112,PPP1CB,MATR3,RBBP4,MIRLET7D,ESR2,USP5,APEX1,DLST,SMU1,MIR363,MYC,CUL3,HNRNPC,ATG101,BTF3,MIR98,RNF40,MCM4,SNRPB,SLC1A3,HNRNPF,RBBP7,G3BP1,VDAC1,SSRP1,HSPD1,EWSR1,PDIA6,SRSF7,CHMP4C,PDHA1,TOP3B,TPBG,NCSTN,LGR4,SUMO2,MAP1LC3A,EED,AK2,DDX23,AGR2,HNRNPD,RB1CC1,HSPB1,LAMP2,IFI16,WWP2,HNRNPA1 |
| 2.900e-06 | -12.75 | SPATS2L (spermatogenesis associated serine rich 2 like) | protein interactions | 26010 | 124 | 59 | 19454 | 5460 |
RPL10A,RPS2,WWP2,IFI16,GRSF1,DDRGK1,CSNK2A1,LYAR,CGAS,RPS10,RPS16,SURF6,KRR1,SRSF1,RPL8,GATAD1,RAF1,ISG15,SOX2,EEF1A1,G3BP1,H3C1,LSM14A,RPL31,LTBR,RPS24,RPL3,DCAF4,H1-1,AP2A1,RPL7A,MYC,AR,ANAPC15,ZNF668,RPGRIP1L,RPL13A,DYRK1A,VIRMA,ESR2,LURAP1,TNFRSF1B,TRIM44,PSPC1,RPS20,FGFBP1,PRKRA,FGFR1,ZNF574,RPL26L1,RPLP0,RBFOX2,RPL4,STAU1,FBXW7,ATP5MK,PML,SQSTM1,HSPA8 |
| 2.921e-06 | -12.74 | FKBP3 (FKBP prolyl isomerase 3) | protein interactions | 2287 | 116 | 56 | 19454 | 5460 |
SMURF1,DYNLL1,RTRAF,CSNK2B,CCNF,OSGEP,PACSIN3,YKT6,STAU1,HSPA8,PMAIP1,BAP1,PEBP1,RFC4,EIF2B3,SNRNP27,CDC42,ATG16L1,PPIA,MDM2,CDK9,CGGBP1,CEP19,ZBTB2,WIF1,SUMO2,EIF2B2,CD274,SYNCRIP,DDX1,NME2,AGR2,PPIB,CSNK2A1,TPM3,HMGA1,CALR,MAP1S,PGAM1,FBXO25,ANP32B,TRIM26,ETFA,HINT2,EWSR1,HNRNPA2B1,ABCF1,MTA2,ILF2,MSX2,ANP32A,RAF1,TOP3B,B3GNT2,TP53,E2F4 |
| 2.950e-06 | -12.73 | MRPS22 (mitochondrial ribosomal protein S22) | protein interactions | 56945 | 271 | 111 | 19454 | 5460 |
FASTKD5,MEPCE,MRPS18C,H3C1,DNAJC30,CLPB,MRPS18B,GFM2,AURKAIP1,METTL15,KBTBD4,TMEM126A,UBL4A,MRPL11,TP53,MRPS23,ZBTB2,SLC25A12,FZR1,CAND1,CGAS,TRMT10B,SRP14,AIFM1,SSBP1,MRPS9,ALYREF,RCHY1,COX4I1,DNAJC4,USP15,CHCHD1,SNRNP70,TMEM70,COPS5,E4F1,GRSF1,CRYZ,HMGB1,SLC25A51,GFM1,SQSTM1,RNF113A,BAP1,HEXIM1,KLF4,MTRES1,HAUS2,MRPS34,METTL14,KLF12,ATG16L1,SMURF1,SRC,VIRMA,MRPS28,PTEN,CCNF,IGF2BP1,DNAJC19,UBE2H,RC3H2,TUFM,MRPS17,IMMP2L,RUVBL1,HINT2,MRPS11,COX8A,HSPD1,LSM14A,NFKBIL1,PDHA1,SOX2,RMND1,GATD3,PHB1,MRPS26,POU5F1,RHOG,HNRNPA1,TRA2A,DDRGK1,MTRF1,MRPS35,RPL6,HSCB,UFL1,NOP53,HSPA8,NGRN,EXD2,TIMM29,DUSP14,APEX1,PRRC2A,ESR2,RPS9,TACO1,CCDC90B,MTG1,MCAT,PSKH1,FBXW11,MRPS25,SNRPB,MYC,AUH,MTG2,PMPCA,CUL3 |
| 2.990e-06 | -12.72 | EIF5A (eukaryotic translation initiation factor 5A) | protein interactions | 1984 | 216 | 92 | 19454 | 5460 |
RPS14,ATG16L1,CFTR,SDCBP,RPA2,LMNA,GRM2,METTL14,HEXIM1,UBE2M,RPA3,SOD1,BAP1,RETREG2,DLAT,DHPS,NONO,PPTC7,BICD2,XPOT,UBE2H,OPTN,PSPC1,STUB1,CTTN,EIF2S2,UBE2I,NDN,SMURF1,PPP1R10,BCCIP,VIRMA,MVD,RPSA,DDX42,RPL23A,LIPA,HUWE1,NUP107,MEPCE,DUSP19,CAPZA1,PPIL4,HDAC6,COPS5,EIF5A2,RPL10A,CDK6,FZR1,TOP1,PRNP,NUP62,NEK7,NUFIP2,CNDP2,DDX39B,HSPA8,UFL1,STAU1,DUSP26,MYC,CUL3,CUL2,BTF3,FAS,DLST,PSMD4,ATP5F1B,ESR2,NAA15,NUP153,MSX2,CHMP4C,DOHH,HSPD1,BCKDK,PICK1,FAM76B,EWSR1,PDIA6,DCP2,UBE2A,NDC80,XPO1,DDRGK1,LBX1,AGR2,PHB1,WDR82,TYMS,SUMO2,NTMT1 |
| 2.990e-06 | -12.72 | DLAT (dihydrolipoamide S-acetyltransferase) | protein interactions | 1737 | 216 | 92 | 19454 | 5460 |
AUH,MTG2,MYC,CDKN3,PMPCA,TACO1,MTG1,DLST,CHCHD3,ESR2,TIMM29,PCLAF,PPT1,HSPA8,PSMA3,RAB5A,NGRN,PRKD3,EXD2,NDUFS2,HSCB,ADRB2,MTRF1,IFI16,MRPS26,CBL,RHOG,TSG101,CORO1C,GATD3,KCTD10,TOP3B,RAF1,EZH2,PDHA1,HINT2,COX8A,UBE3A,HSPD1,TRIM37,TUFM,CSK,UBE2H,CCNF,VIRMA,STAT5A,CFTR,RARS1,MTRES1,CYC1,HECTD1,RPA2,METTL14,GFM1,RAB9A,BAP1,DVL2,RPA3,SIRT7,PML,CRYZ,PDHB,NF2,HMGB1,COPS5,HDAC6,ATP1B1,KARS1,DPP4,EMC4,DNAJC4,USP15,CHCHD1,EXOC2,LDLR,SYNCRIP,SDHB,SSBP1,COX4I1,LMAN1,MDM2,MIF,PRNP,AURKAIP1,UBR7,METTL15,MRPL11,HAPSTR1,DHX9,SFXN1,FASTKD5,CAPZA1 |
| 2.990e-06 | -12.72 | spliceosomal snRNP complex | cellular component | GO:0097525 | 75 | 41 | 19108 | 5553 |
SNRPD2,LSM6,DDX39B,PPIH,RBMX2,SNRPA1,SNIP1,CD2BP2,SNRNP70,LSM2,SF3B6,LSM4,SNRNP27,PRPF4,PRPF31,SNRPB2,USP39,LUC7L3,SNRPE,SNRPG,SNRPA,LSM5,SNRPD1,LSM3,SNRPB,SNRPD3,DDX46,SNRNP40,DDX23,TSSC4,SF3B1,RBM42,TXNL4A,SF3B4,PRPF18,LSM8,SF3B5,SART3,ZMAT2,SF3A1,SNRPN |
| 3.018e-06 | -12.71 | positive regulation of blood vessel endothelial cell migration | biological process | GO:0043536 | 79 | 43 | 18204 | 5365 |
NFE2L2,NRP1,TMSB4X,VEGFA,MIR210,MIR10B,MIR150,NUS1,GAB1,PRKCA,MIR31,RHOJ,MIR342,FOXC2,MIR221,MIR296,SP1,STAT5A,MIR146A,MIR30A,FGFBP1,MIR101-1,MIR200A,MAP2K3,MIR126,MAP3K3,ATP5F1B,MIR143,HSPB1,MIR135B,ATP5F1A,HMGB1,FGFR1,CD40,ANGPT1,AKT1,MIR132,AKT3,MIR10A,VEGFC,PLG,MIR23A,MIR939 |
| 3.033e-06 | -12.71 | CELF1 (CUGBP Elav-like family member 1) | protein interactions | 10658 | 277 | 113 | 19454 | 5460 |
NCOA5,LARP4B,MRPS7,G3BP2,YTHDF1,STAU1,DDX5,MCRIP2,MIR363,DCAF4,RBM27,MRPS25,HNRNPC,HNRNPAB,TOM1L1,PRRC2A,RABIF,ESR2,MATR3,MIRLET7B,EZH2,KIF2A,TOP3B,RBM12,CCAR1,MRPS17,DMPK,HNRNPDL,G3BP1,HNRNPF,MIR155,NUP42,EWSR1,ZC3H7A,MIR206,MIR9-2,HNRNPA2B1,LSM14A,PABPC1,CDKN1B,MIR221,MRPS26,HNRNPD,MIR140,MIR31,PSMD10,HNRNPA1,MIR29C,VPS26A,MIR143,MRPS35,HNRNPL,CCAR2,MIR9-1,MIR214,FUBP3,RBM5,MIR7-2,MIR21,MIR7-1,MRPS34,RPA2,AGO1,RBMS2,CPSF4,MIR34B,EIF4E,MIR107,MIRLET7I,LSM12,SMG5,UGDH,MIR10B,RPA3,PML,MIR205,IGF2BP1,UBE2H,CDKN2AIP,RC3H2,NONO,SUGP1,CEP85,CSTF3,MRPS28,PSPC1,CCNF,SMAP2,ILF2,CERK,CDK8,MIR17,WBP11,ESS2,STRBP,YTHDF2,TNRC6C,RIGI,HNRNPK,RPIA,MRPS18B,PQBP1,MIR34A,PPIL4,MOV10,GRSF1,MRPS23,MIRLET7G,MIR25,SYNCRIP,MRPS9,MIR106B,ALYREF |
| 3.044e-06 | -12.70 | ASCC3 (activating signal cointegrator 1 complex subunit 3) | protein interactions | 10973 | 182 | 80 | 19454 | 5460 |
G3BP2,TRIM52,STAU1,FBXW7,KDM1A,NPM3,FXR2,THBS3,NOG,SIRT7,BAP1,RPA3,USE1,CDK1,RPA2,SEC22B,ALKBH3,ATG16L1,PABPC5,VIRMA,ESR2,RBBP4,FBXO22,NDN,PHF21A,PTEN,RPS20,GSK3A,METAP2,CIB2,ENO1,LMBR1L,RPS3,PSPC1,CCNF,UBE2H,DCAF4,EIF3G,ASCC1,BTF3,CUL3,PYCR1,MYC,PTGES3,RPS13,FARSA,G3BP1,BAG2,PABPC1,RINT1,TRIP4,RPS11,EZH2,LGR4,ISG15,SOX2,OTUD6B,ZNF263,RAF1,CGAS,SPPL3,TTC9C,RPS10,CAND1,RPS16,PAIP1,RPLP1,EEF1AKMT3,FBXO32,DCAF11,RPS2,DNAJC7,CDK12,SKIC8,XPO1,HSPB8,WWP2,UBXN6,MOV10,IFI16 |
| 3.047e-06 | -12.70 | VANGL2 (VANGL planar cell polarity protein 2) | protein interactions | 57216 | 168 | 75 | 19454 | 5460 |
OTULIN,RND3,RAB4A,CTLA4,RP9,RPN1,NFKBIL1,TMEM59,DNAJC25,JPH4,FLOT1,TMED7,AP1M1,KRAS,ARGLU1,TMT1A,BRD3,ESYT1,RHOG,LAMP3,ZCCHC10,RAB5C,LAMP2,DPP4,SYNJ2BP,CAV1,TMPO,STX6,LMAN1,DIRAS3,TNFSF18,RHOH,ARF6,DNAJC1,RAC2,SPINT2,HSD17B11,GJA1,SDC4,RAB35,PTPN1,KCNA2,SSR1,SDC2,ST7,CDC42,SEC62,RND2,OTULINL,RNF41,STX7,SAP18,DERL1,RAB9A,SQSTM1,RAB5A,HSPA8,DVL2,RHOU,TEX264,RHOB,LAMTOR1,HFE,DNAJC5,RAB11A,RAB2A,RPL22,SEC63,RHOJ,POPDC2,MANSC1,SEC61B,RMDN3,TNFRSF1B,CD79B |
| 3.047e-06 | -12.70 | KPNA6 (karyopherin subunit alpha 6) | protein interactions | 23633 | 168 | 75 | 19454 | 5460 |
KPNA2,CSE1L,CDK2AP2,RBBP7,G3BP1,ANP32B,MEPCE,MAP1B,SREK1IP1,HAPSTR1,CACUL1,CBX3,NUPR1,SMARCB1,CARD19,RAF1,ANP32A,KBTBD4,MAP1LC3B,NUP153,GFPT1,CD2BP2,LYAR,NOP58,MEAF6,MDM2,NCBP2,CTDSPL2,KLHL7,COPS2,H2AC4,ARMC8,KPNA1,TAF9,CDKN1B,NT5C2,PPM1D,COPS5,HMGB1,PHB2,IL1A,IRF3,RPA3,PPM1G,BAP1,NUP50,RAMAC,TTC1,EXOSC4,LMNA,CFTR,FBXO22,RBBP4,SNRNP40,RANBP6,STAT1,VIRMA,DYRK1A,RAN,SURF2,CCNF,LMBR1L,PSPC1,LMNB1,BRCA1,SPOP,FAS,RIT1,ALKBH5,PTTG1,MORF4L1,CUL3,CREBBP,PPP1CC,NONO |
| 3.081e-06 | -12.69 | Regulation of toll-like receptor signaling pathway | WikiPathways | WP1449 | 145 | 79 | 5310 | 1910 |
IFNA13,MIR98,MBL2,CXCL11,IFNA2,TIRAP,TOLLIP,TLR5,TBK1,TAB1,IL1B,JUN,TLR8,PIK3R2,PIK3CG,TLR4,PIK3R1,TRAF6,IKBKB,SARM1,CCL5,ZMYND11,MYD88,TICAM1,TLR1,TLR3,RBCK1,AKT1,CD80,MAP2K1,IL6,IL12B,MAP2K6,MAP2K3,TRAFD1,PIK3CA,LY96,SYK,PELI1,TMED7,TNF,TNFAIP3,IRAK4,CISH,CD14,NFKB1,MIRLET7I,TIFA,CXCL10,NFKBIA,IFNA10,IFNB1,IFNAR1,AKT2,CD86,SPP1,MIR105-1,TLR2,TICAM2,STAT1,TLR7,IL12A,SFTPD,PELI3,RNF41,CCL3,IRF3,PIK3R3,CXCL8,SQSTM1,CD40,TLR9,FOS,CXCL9,MAPK10,TAB2,TLR6,AKT3,IRF7 |
| 3.085e-06 | -12.69 | BCKDK (branched chain keto acid dehydrogenase kinase) | protein interactions | 10295 | 135 | 63 | 19454 | 5460 |
DYNC1I2,ADCK1,HSP90AB1,CETN2,SSBP1,TIMM8B,AIP,FAHD1,CETN3,AK2,PPM1K,ARMC8,MAP4,PFDN5,FAM174A,CBR4,TPM3,RASL10B,TMEM33,IL12A,PTGES3,DMPK,NDUFA4,SLC25A10,HSPD1,MRPL52,PDHA1,CAMK1,GNAI3,NUDT16,RAF1,TIMM8A,GNAI2,ESR2,PDCD5,TECR,GNG12,CAB39,STN1,SDF2L1,TAFAZZIN,SMPD2,HSP90AA1,MRM2,EPS8,CUL3,SLC25A1,MTG2,FBXO7,SSR3,FBXW7,GCNT3,FXR2,LSM8,AMACR,EXD2,SQSTM1,SSR1,QRSL1,ATG16L1,MRPL12,HCST,TIMM13 |
| 3.126e-06 | -12.68 | Spliceosome | KEGG pathways | ko03040 | 132 | 71 | 7161 | 2463 |
LSM5,CDC40,PRPF19,PQBP1,CDC5L,TXNL4A,LSM2,SRSF2,CTNNBL1,SMNDC1,DDX5,THOC2,SNRPE,SNRPB2,DDX42,PRPF4,SNRPD1,SF3B1,THOC3,SF3B5,USP39,SNRPA1,SRSF7,SRSF4,DDX39B,HNRNPC,HSPA8,EIF4A3,CWC15,SNRPG,SNRPB,SRSF1,MAGOHB,DDX46,TRA2B,SF3B6,RBM17,DHX16,LSM3,PRPF18,SRSF8,WBP11,PRPF31,DDX23,LSM8,LSM4,MAGOH,SRSF10,SNRPD2,SNRPD3,SNRNP40,SNRPA,PPIH,THOC1,ZMAT2,HNRNPK,SNRNP70,DHX38,TRA2A,DHX15,LSM6,RP9,ALYREF,SF3B4,RBM22,NCBP2,SLU7,HNRNPA1,BUD31,SF3A1,SNRNP27 |
| 3.126e-06 | -12.68 | Spliceosome | KEGG pathways | hsa03040 | 132 | 71 | 7161 | 2463 |
CTNNBL1,SMNDC1,LSM2,SRSF2,SNRPE,SNRPB2,DDX42,PRPF4,SNRPD1,DDX5,THOC2,CDC40,PRPF19,LSM5,CDC5L,TXNL4A,PQBP1,SNRPA1,SF3B5,THOC3,USP39,DDX39B,HNRNPC,HSPA8,SRSF7,SRSF4,SF3B1,PRPF31,DDX23,PRPF18,SRSF8,WBP11,MAGOH,LSM4,SRSF10,SNRPD2,LSM8,SNRPB,SRSF1,MAGOHB,DDX46,TRA2B,CWC15,EIF4A3,SNRPG,DHX16,LSM3,SF3B6,RBM17,NCBP2,SLU7,ALYREF,SF3B4,RBM22,SNRNP27,HNRNPA1,BUD31,SF3A1,ZMAT2,SNRPD3,SNRNP40,SNRPA,PPIH,THOC1,DHX15,TRA2A,LSM6,RP9,HNRNPK,DHX38,SNRNP70 |
| 3.160e-06 | -12.67 | MCCC2 (methylcrotonyl-CoA carboxylase subunit 2) | protein interactions | 64087 | 146 | 67 | 19454 | 5460 |
WWP2,AGR2,HSPB1,POU5F1,HNRNPD,DNAJC4,DNAJC7,PHB1,NAP1L5,DNM2,PREP,EED,PRNP,HNRNPL,NDUFS8,EGLN3,TP53,YTHDF2,RAF1,KBTBD4,HDAC11,PDHA1,CYB5B,HSPD1,PC,EMC2,TOLLIP,HUWE1,PMPCA,CUL3,CARS1,NDUFB10,MYC,PCCB,DCAF4,TRIM23,UBE2H,EIF2AK2,CCNF,PTEN,UBASH3B,PHF21A,SMU1,LGALS3,ATP5F1B,TXN,ESR2,PAFAH1B1,SSBP2,DET1,CFTR,FBXL19,RPA2,NDUFA5,ACACA,PIH1D1,NLE1,RPA3,INPPL1,DVL2,EP300,RNF113A,HSPA8,HSPB2,ATP5F1E,ADRB2,KDM1A |
| 3.203e-06 | -12.65 | NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13) | protein interactions | 51079 | 127 | 60 | 19454 | 5460 |
MTMR12,NDUFV2,AGR2,ATP6V1D,COX4I1,AIFM1,NDUFA1,SLC25A12,COX14,NDUFS8,EGLN3,NDUFA2,DUSP1,APOO,AURKAIP1,NDUFS6,NDUFS3,NDUFA12,ATP5PF,NDUFA4,SFXN1,NDUFB5,SLC25A10,HSPD1,UBE3A,CLPB,ABCE1,DNAJC30,KRAS,HUWE1,RIGI,TXNRD2,PYCARD,NDUFB10,NDUFB6,UBE2H,HTRA2,EPHA2,CCDC90B,CCNF,LMBR1L,CPT2,SLC22A12,PARL,NDUFAF4,TPT1,TIMMDC1,NDUFAF3,TIMM23,RPA2,NDUFA5,TMOD1,SCLT1,RPA3,NDUFC2,TMEM126B,HSPB2,FBXW7,NDUFS2,HSCB |
| 3.210e-06 | -12.65 | NFKB1 (nuclear factor kappa B subunit 1) | protein interactions | 4790 | 292 | 118 | 19454 | 5460 |
SMAD4,IRF9,NFKB1,COPS5,COMMD5,PRNP,TSC22D3,DCUN1D1,CDK9,ILVBL,EEF1AKMT3,HACD3,ARL4D,PIK3CA,PPP4C,PPME1,TAB2,COMMD8,FBP1,TBK1,SOCS3,KPNA2,CNOT7,CNOT6L,GLUL,NKRF,BICD2,TNFAIP3,PCBD1,AR,FBXO7,MTPN,ADRM1,TXN,STAT5A,VIRMA,TECR,RPS3,PELP1,STUB1,SF3B6,IL2RA,SEC61A1,SSR1,STAT6,CCN3,CXCL8,COMMD3,HMGB1,FBXW7,RPS15,HDAC3,GTF2I,UBE2K,CLU,ABCC2,TMUB1,PML,PSMD10,IKBKB,VPS26A,RPL6,CNOT2,UBXN6,HMGA1,QPCTL,CTNNB1,XPO1,COMMD6,RPS10,HSP90AB1,DHX15,ANXA4,WDR6,IRF8,HGS,PLD3,CCR1,MTMR2,VDR,ELF1,SERPINA3,JUN,HNRNPF,ATF3,TRIP4,JAK1,RUVBL2,FBXW11,BRCA1,COMMD9,POLR1B,SP1,NTRK3,PSMA4,CUL3,MYC,GGH,BRMS1,IRF1,TUBB,NFKBIB,CNOT6,NFKBIA,IRF2,PALS2,PPARG,CDKN1A,PPP1CB,ATAD1,UBE2D3,SKP1,G3BP2,FOS,DDX5,EP300,COMMD2,HDAC5 |
| 3.222e-06 | -12.65 | UBXN7 (UBX domain protein 7) | protein interactions | 26043 | 171 | 76 | 19454 | 5460 |
TNFAIP1,NUP50,NUBP2,APPBP2,BIRC2,OXCT1,NSFL1C,LZTFL1,UCHL3,SKP1,RPA2,LMNA,VAPB,CSNK1G3,QNG1,FAM91A1,SRXN1,SYT2,ACTB,SNRNP40,KBTBD2,RANBP6,VIRMA,ESR2,SMURF1,UBE2L3,UBE2V2,CUL2,CUL3,MYC,CSK,UFD1,LMNB1,DCAF4,SETD7,ABCF1,ZYX,FAF1,FAM168A,NEDD8,UFM1,PAX6,CSNK1E,TULP3,UBE2V1,TRIM62,JUN,SOX2,FAF2,UBE2B,TMEM31,CBX3,ZNRF1,RAD23B,KLHL12,TOPORS,ZRANB2,SEC23A,SDHAF2,TYMS,KCTD10,CAV1,WIF1,VPS26A,TRIM8,ERCC3,TCEANC2,ATG9A,KLHL22,WDR11,ELOC,TRAF6,UBE2D1,IKBKB,MUL1,VCPIP1 |
| 3.251e-06 | -12.64 | USP32 (ubiquitin specific peptidase 32) | protein interactions | 84669 | 111 | 54 | 19454 | 5460 |
OXSR1,FDFT1,CDK1,ZDHHC17,NME4,GTF2I,SLC31A1,RAB9A,DVL2,TRIM3,LAMTOR1,RHOB,MYC,HSPA14,RAB11A,CUL3,DYRK1A,SRC,ESR2,VIRMA,SNX3,MANSC1,TRIM46,FBXO22,MID1IP1,EIF2AK2,RAB6B,TUBA1A,RIGI,RDH11,KRAS,RBCK1,FARSA,EFNB1,CD83,VCPIP1,NAB2,YWHAB,USP15,LAMP3,UBXN6,ATG9A,LAMP2,CX3CL1,CAND1,MAPRE2,RAP1B,KRT8,HRAS,RAB35,SYNCRIP,PTPN1,FBXO32,EEF1AKMT3 |
| 3.264e-06 | -12.63 | TALDO1 (transaldolase 1) | protein interactions | 6888 | 119 | 57 | 19454 | 5460 |
PGM1,SOX2,RAF1,SPC24,PDE6D,EZH2,CBX3,PLS3,UBE3A,IDH1,EWSR1,SCYL2,RIGI,HSPE1,AGR2,MTAP,DCK,ZHX1,CAV1,RPE,AKR1A1,RPA2,ADSS2,LDHAL6B,PMAIP1,CFDP1,COX17,HSPA8,PSMG4,NMRAL1,INPPL1,RPA3,BAP1,LSM8,BCL6,CSRP1,OXCT1,RNF40,PRKACB,LDHB,SORD,PNPO,PEA15,CHRAC1,BRCA1,GLOD4,CHORDC1,TRIM24,ZNF655,GSK3A,PITPNB,WDR45,ENO1,CYRIB,TUBB,LDHA,PRDX2 |
| 3.270e-06 | -12.63 | cellular response to toxic substance | biological process | GO:0097237 | 127 | 62 | 18204 | 5365 |
GSTK1,GPX5,HBB,TXNRD2,SOD1,TXNRD3,GPX4,NQO1,GSTO2,HBE1,GSTA1,IPCEF1,SESN2,MGST2,SELENOW,CYP1B1,GSTO1,MTARC2,HBM,AKR1A1,SRXN1,CCS,GPX3,HP,ALOX5AP,MGST3,GSTT1,CLIC2,PRDX4,ABCG2,PRDX6,LANCL1,GPX2,SELENOS,SELENOT,PRDX1,GPX7,GPX6,PRDX2,RDH11,GSTM2,ESD,SOD3,HBA1,SELENOF,TXNRD1,TP53INP1,CYGB,RAB29,GSTP1,RDH12,TXNDC17,TXN,SOD2,MT3,GPX1,PRDX3,PTGES,ALB,UBIAD1,GSTM3,TNF |
| 3.271e-06 | -12.63 | viral process | biological process | GO:0016032 | 243 | 105 | 18204 | 5365 |
CCR5,SIVA1,PLSCR1,JPT2,DPP4,BECN1,NUP153,FUT8,EDEM2,CAV2,CTSB,NRP1,TNFRSF14,CCL2,TSG101,IRF7,MGAT4A,KPNA6,SPCS1,GSK3A,EIF3G,MRC1,CTBP1,VPS28,DHX9,EIF2D,EPHA2,VAMP8,RAB1B,AKT1,CXCR6,ITGB5,GPR15,ITGA2,HCFC2,VPS4B,CXCR4,GTF2B,EIF3D,ST6GALNAC3,RPSA,CD209,LAMP3,TRIM62,PHB1,TFRC,CLDN9,AVPR1B,HYAL2,WWP1,CCL1,CHMP5,RAN,F11R,CD4,MGAT1,CSNK1A1,CD81,ST3GAL2,DEK,CD46,IDE,CLDN1,CHMP4C,SMARCB1,FURIN,PC,CHMP2A,CAV1,KPNA2,ST3GAL1,MOG,VPS18,RAB1A,CHMP2B,CD80,HSP90AB1,CLDN6,CHMP1B,DAG1,LDLR,HTR2A,USP6NL,CDK1,PPID,ITGAV,JUN,MGAT4B,NECTIN2,RNASEK,PARD6A,ST3GAL4,ICAM1,SPCS3,GALNT1,TP53,WWP2,ST6GAL1,SLC7A1,SLC20A2,PAIP1,CD86,PPIA,VPS4A,CHMP1A |
| 3.297e-06 | -12.62 | NENF (neudesin neurotrophic factor) | protein interactions | 29937 | 85 | 44 | 19454 | 5460 |
DNAJC10,CALU,RPS26,ACO2,MYC,TUFM,TXNDC12,MRPL23,CLIC4,ENO1,SEC61B,IDH2,JUP,GSTP1,SPR,DDAH1,SPTBN1,CNPY3,NDUFAB1,HSPA5,POLDIP2,TMEM106B,SOD1,DPH6,AKAP1,PRDX6,RPS2,PRNP,SPTAN1,UQCRH,RPL32,HDHD3,SELENOM,GATD3,IGBP1,MRPL49,ILF2,RPSA,SUPT5H,CPLX1,MPST,HINT1,HINT2,RPL3 |
| 3.312e-06 | -12.62 | ENG (endoglin) | protein interactions | 2022 | 205 | 88 | 19454 | 5460 |
TOMM40,CFAP20,PMPCA,TMED4,CHCHD3,LGALS3,TSN,EFHD2,ESAM,PAFAH1B1,TGFB1I1,CCND3,WASF3,NUP50,NUBP2,TMEM106B,FAM168B,MRPS26,TGFB3,LYZ,TGFB2,NDUFV2,NGDN,LRWD1,LANCL1,NOB1,LYAR,PSME2,RNF126,EXOSC3,FOXJ3,SPC24,EMC8,MAPK1IP1L,TRIM21,PRPSAP1,VPS26B,SLC25A5,BCKDK,LSM14A,RBM7,MAPRE1,CDKN2AIP,SORD,TUFM,SMAD5,UBA3,DDAH2,TXN,ABHD14B,MOB4,GTF2H2,CDK1,CHMP1A,COMMD3,RBMS2,SEC22B,EEF1E1,MBD3,EGFL7,SPCS2,MAIP1,GLIPR1,TAF9,CLP1,BCL10,LYPLAL1,MRPS23,MRPL24,PLEKHF2,DSTN,SDHB,GTF2B,HCLS1,CAPN2,ACVR1,BMPR2,SMAD1,ATP5PB,ARF4,RPIA,FN3KRP,TGFBR2,TMEM33,MRPS18B,SNAP23,MAP1B,TCOF1 |
| 3.312e-06 | -12.62 | AMFR (autocrine motility factor receptor) | protein interactions | 267 | 205 | 88 | 19454 | 5460 |
CFTR,UBE2W,PRKCA,PDIA2,HSP90B1,DERL1,MAVS,SPCS2,SCN1B,SYVN1,FADS2,APMAP,SOD1,HSPA5,TMUB1,UBE2K,PSMB2,ATL1,PSMA6,CCL1,TXN,COPE,EEF1A1,DUSP1,INSIG2,PREB,CCDC47,UBL4A,SPRY1,TMEM165,FAF1,MDC1,SRPRB,CSE1L,PSMA5,EDEM1,SELENOS,OSBPL8,PSMB1,UBE2N,UBE2G2,AIFM1,PRNP,SVIP,DERL2,GLRA2,PGRMC1,PSMB3,UBAC2,PSMB7,PSMA3,ADRB2,RNF5,UBE2D3,UFD1,HSD17B3,PSMA4,USP13,CRMP1,PSMD14,WDR20,SEC61B,LMBR1L,APLNR,PSMB6,TOM1L1,PSMD6,ERLIN2,FAF2,OR4N2,STMN2,HSPD1,HS2ST1,RPS27A,PSMA1,PSMA2,CTNNB1,PMP22,PSMD3,ATG9A,HAX1,UBE2D1,PSMB5,PSMB4,KCNA2,OS9,ERLIN1,TCP1 |
| 3.324e-06 | -12.61 | SLC20A2 (solute carrier family 20 member 2) | protein interactions | 6575 | 65 | 36 | 19454 | 5460 |
PTGFR,FURIN,RAB4A,CDC42,RND2,CLDN4,TOR1AIP2,STX7,KRAS,SLC22A6,RAB9A,RAB5A,NTRK2,RHOU,CCR5,SLC20A1,LAMTOR1,RHOG,SYP,RHOB,LAMP3,MOV10,RAB2A,LAMP2,RAB11A,RAB5C,OPRL1,ARF6,RHOJ,ARMC6,RHOH,NRSN1,RAC2,HRAS,RAB35,AIFM1 |
| 3.339e-06 | -12.61 | LACTB (lactamase beta) | protein interactions | 114294 | 188 | 82 | 19454 | 5460 |
MYC,AUH,NDUFB10,PYCR1,PCBD1,TUFM,HMOX2,CHCHD4,HTRA2,UQCRC2,GNPDA1,TSN,CHCHD3,TCEAL7,PARL,ESR2,TIMMDC1,MTX2,PRDX3,UQCRC1,TIMM13,TIMM29,COX6C,SAMM50,ARMCX3,WWP1,CYC1,EXD2,HSPB2,MED13L,PDHB,NME4,NDUFS2,HSCB,PHB2,NSFL1C,STAU1,SLC25A51,POLDIP2,FTL,COX5A,WWP2,NDUFV2,HDAC6,DDRGK1,CTNNB1,AK2,POR,HAX1,DNAJC4,AIFM1,FBXO32,PHB1,COX4I1,CORO1C,PRNP,CGAS,TOMM70,NDUFS8,COX14,SLC25A12,RAF1,TP53,SOX2,APOO,MTARC2,UBXN2B,TIMM8A,NUDT19,NDUFS3,SFTPC,CAPN2,SLC25A24,GLUL,SFXN1,CLPB,EMC2,COX8A,TNF,USP30,KCTD17,IMMP2L |
| 3.354e-06 | -12.61 | NPM3 (nucleophosmin/nucleoplasmin 3) | protein interactions | 10360 | 257 | 106 | 19454 | 5460 |
ARGLU1,RPL31,EWSR1,H1-6,RPL28,MRPS17,UBE2A,RAF1,MAK16,GLE1,EZH2,RPL18,RPL9,RPL8,RPLP2,HP1BP3,EED,MAGED2,HSP90AB1,RIOX2,RPL6,DDX50,DDRGK1,WDR12,EEF1G,NOP53,STAU1,UFL1,RPP14,MAP2K1,TPD52L1,PIH1D1,IRF2BPL,ZNF22,RPS9,RPL37A,RPL7L1,RPF1,ATP5F1B,RPL19,RPL10,NOP16,MYC,ZNF668,FTSJ3,FAS,NSA2,NKRF,RPL23A,RPL3,MRPS18B,SCML1,PAK1IP1,RPL17,MEPCE,MRPL47,IMP3,POP5,RPL15,H2AX,TAF1D,MAP2K3,RBM34,SRP72,RPL32,RPL12,FZR1,MRPS23,SURF6,MRPL24,CDK9,MPHOSPH10,RPL10A,NOL12,PNO1,NLE1,RPL27,BAP1,RHOU,RNF113A,MRPL41,RPL4,RPS15,MRPL20,BRIX1,AATF,WDR55,ATG16L1,UPRT,ZNF574,NOL7,RPLP0,RPL26L1,HEXIM1,PELP1,SENP5,PTEN,RPS20,PRKRA,RPP25L,RPL13A,RSL24D1,RPP25,RPF2,UBE2H,PDCD4 |
| 3.359e-06 | -12.60 | SYAP1 (synapse associated protein 1) | protein interactions | 94056 | 138 | 64 | 19454 | 5460 |
TMT1A,SFXN1,UBE3A,BAG2,IGF1R,RAB3B,ADIPOQ,KRAS,PSMA5,DHX38,MTCH2,PTRH2,STIM1,RPN1,CBX3,FURIN,PSMB4,PTPN1,RAC2,HSD17B11,RPL35A,PLGRKT,COX14,STX6,SLC25A46,LAMP2,MFN1,LAMP3,XPO1,RHOG,RPA3,BAP1,AKAP1,RAB5A,RAB9A,DERL1,SYVN1,STAU1,ATAD1,CERS2,TOMM20,STX7,BET1,TOMM22,ETF1,RND2,SNRNP27,CDC42,SEC62,SSR1,FGFR1,PSMB7,RPA2,CCNF,SEC61B,GSK3A,PSMD6,MGST3,NDN,RAB11A,CYP1A1,LAMTOR1,NTRK3,FIS1 |
| 3.363e-06 | -12.60 | MCM7 (minichromosome maintenance complex component 7) | protein interactions | 4176 | 394 | 152 | 19454 | 5460 |
SNRPA1,HSP90AB1,SRSF10,EGLN3,PHB1,SP2,TSG101,TRAF6,AGR2,DDX23,HSPB1,NAB2,AHSA1,CDKN1B,VPS26A,HMGA1,LAMP2,IFI16,CTNNB1,DDRGK1,CNOT8,ASF1A,KRAS,G3BP1,SSRP1,RAD21,SAR1B,PSMD12,MCM6,TOP2B,RINT1,UBE3A,ACTR1B,ZC3H7A,PCNA,H2BC1,EZH2,STK16,MOB3C,E2F4,RBBP4,SNRNP40,RANBP6,PELO,NFKBIA,PNMA1,PHF21A,SMU1,CDC7,MCM8,RIT1,POLR1B,COP1,CUL3,MYC,MCM4,BAG3,MCM3,BTF3,MCMBP,STAU1,RP2,UFL1,COIL,GINS3,DDX39B,EP300,DDX5,HSPA8,SF3B1,HDAC5,CRY1,PPARG,PAFAH1B1,ASB8,LNX2,MIF,MAPRE2,TOP1,FZR1,ZBTB2,TMPO,ARL10,CD274,H2AZ1,RB1,DSTN,H2AC4,USP15,SSX2IP,ORC5,ELOC,HDAC6,COPS5,CCL2,TRIM63,H3C1,TNFSF8,MNAT1,PTGES3,FBXO25,VTA1,MAP1B,SOS2,CPNE2,HAPSTR1,GINS4,RNF181,ILF2,TP53,ACTR1A,H2AX,NDN,TRIM54,VIRMA,SRC,SMURF1,CCNF,TRIM24,PTEN,RTRAF,TRIM27,STK24,TXNIP,SNTA1,UBE2H,GSTK1,SLC25A1,AR,FBXO7,FBXW7,NUCKS1,KDM1A,MBD3,PIAS1,SIRT7,RPA3,ORC6,BAP1,DVL2,RNF113A,GRM2,RPA2,HAUS2,ACACA,TFIP11,CCND1,SF3A1,CFTR,CDK7,CDC42,CCNH |
| 3.380e-06 | -12.60 | NFU1 (NFU1 iron-sulfur cluster scaffold) | protein interactions | 27247 | 53 | 31 | 19454 | 5460 |
HIRA,ZSCAN5A,HSCB,REXO2,COIL,ABHD10,AGTRAP,PDHA1,APOC2,MET,SOD2,TFIP11,APOC4,PTEN,GATD3,SH3BP4,ACO2,CIDEB,MTG2,AUH,HMGCS1,CUTA,DESI2,TRIM23,NOA1,OAT,HSPB1,MDH1,ZNF688,YWHAB,HTRA2 |
| 3.381e-06 | -12.60 | protein-RNA complex organization | biological process | GO:0071826 | 210 | 93 | 18204 | 5365 |
BRIX1,ZNHIT6,SF3A1,LSM4,PRMT5,DHX9,EIF2D,NOP53,EIF3J,CLP1,RUVBL1,LSM2,MRM2,TAF9,WDR77,EIF3D,SF3B1,SRPK2,RPSA,GEMIN8,SNRPD3,XRCC5,RPS28,SF3B5,TXNL4A,DICER1,PRPF31,SART3,SNRPD1,CD2BP2,SNRPA1,SNRPE,RPL6,PRPF18,PIH1D1,EIF3G,RBM5,SNRPD2,COIL,PPAN,PRPF19,RPF2,GCFC2,SRSF12,SNRPB,TRIM21,PWP2,USP39,SMN1,RPS15,SF3B6,TRAF7,EIF2S2,HSP90AA1,TSSC4,RBMX2,SF3B4,LUC7L3,MRPS7,RRP7A,SNIP1,GEMIN7,SRSF1,PTGES3,ZNHIT3,SLU7,FAF2,DDX39B,AGO1,RPL23A,PRKRA,DDX42,RPS14,DDX1,SNRPB2,DDX23,NLE1,EIF3K,RPS27L,SNRPG,RPL10L,TFIP11,DDX46,RPL10,NOPCHAP1,RPLP0,SRSF10,RUVBL2,CELF6,RPS5,HSP90AB1,EIF3E,KHDC4 |
| 3.399e-06 | -12.59 | MRPS6 (mitochondrial ribosomal protein S6) | protein interactions | 64968 | 174 | 77 | 19454 | 5460 |
RMND1,MRPS23,DBT,DYNC1I2,MRPL50,FZR1,GATD3,ALYREF,SSBP1,MRPS9,MRPS26,TMEM70,SNRNP70,CHCHD1,RHOG,TRA2A,MRPS35,GRSF1,MTRF1,IMMP2L,MEPCE,MRPS18C,FASTKD5,MRPS17,MRPS33,MRPS11,HINT2,MRPS18B,PSME1,RBM3,HSPD1,RNF181,GFM2,PDHA1,METTL15,AURKAIP1,APOBEC3D,MRPL11,RPL10,SRPK2,LRIF1,SMURF1,STAT5A,MRPS21,MTG1,CCDC90B,TACO1,MCAT,DNAJC19,UBE2H,IGF2BP1,RC3H2,MRPS25,NOA1,MRPS16,TUFM,BTF3,CUL3,PMPCA,AUH,MTG2,MYC,CRYZ,MRPS7,FBXW7,HSCB,GFM1,PRKCB,EXD2,NGRN,CORO6,BAP1,MTRES1,FGFR1,MRPS34,KLF12,TIMM29 |
| 3.400e-06 | -12.59 | SLC30A9 (solute carrier family 30 member 9) | protein interactions | 10463 | 149 | 68 | 19454 | 5460 |
FASTKD5,FKBP8,IMMP2L,TNFSF8,DNAJC30,HINT2,COX8A,SFXN1,GFM2,RPN1,GLE1,AQP3,PDHA1,APOO,COMTD1,MRPL11,LMAN1,EGLN3,NUF2,DHX15,RMND1,ARF6,HSD17B11,GATD3,SSBP1,AIFM1,COX4I1,DNAJC4,MRPS26,RHOG,TMEM70,CHCHD1,LAMP3,COPS5,CTNNB1,GRSF1,LAMP2,MTRF1,MARCHF5,RAB5C,SLC25A46,COX5A,PXMP2,HSCB,SLC25A51,PHB2,AKAP1,GFM1,TSPAN15,MTRES1,OTULINL,KLRD1,ST7,PARL,KCTD9,SEC61B,TACO1,LMBR1L,CCDC90B,STK11,DNAJC19,HTRA2,SMPD2,TUFM,RAB2A,MTG2,AUH,PMPCA |
| 3.400e-06 | -12.59 | IGBP1 (immunoglobulin binding protein 1) | protein interactions | 3476 | 149 | 68 | 19454 | 5460 |
CUL3,SFN,RIT1,PFDN6,PFDN2,PAIP2,S100A11,CCT2,POMP,SNX12,SRXN1,CCNF,SH3BGRL,SNX3,LGALS3,PYGM,TAGLN2,STAT1,TOM1L2,STAT6,PSRC1,VPS4B,EP300,MEA1,NUBP2,PML,RPA3,PEBP1,GINS3,MBD3,GLO1,HSPB1,UBE2D1,RPLP1,TES,TYMS,EEF1AKMT3,SRSF1,NHEJ1,PPP2CB,SIN3A,CCT7,NOP9,PPIA,MYL12A,EGLN3,MIF,TCP1,SUMO2,CCT5,PPIL3,RBM12,KBTBD4,RAD23B,PPP4C,UBE2B,STMN2,GINS4,PDIA6,EWSR1,CCT8,PABPC1,RIGI,FBXO25,PFDN1,CAMK2G,NEDD8,KRAS |
| 3.412e-06 | -12.59 | LACTB2 (lactamase beta 2) | protein interactions | 51110 | 80 | 42 | 19454 | 5460 |
NUDT19,ISOC1,GSTP1,FKBP1A,CMPK1,LAP3,SPR,DDAH1,GLRX5,NDUFAB1,MYH1,GUK1,COIL,LYPLA2,MPST,CRYZ,SOD1,PALM2AKAP2,HINT2,TXNL1,HINT1,PRDX6,AK2,TST,MDH1,UBE2H,FXN,PMPCA,MTPN,ISCA2,AKR1C2,CTSB,SIAH1,CLIC4,DDAH2,FABP5,SSU72,HDHD3,ENO1,COX4I1,CMBL,GATD3 |
| 3.435e-06 | -12.58 | response to toxic substance | biological process | GO:0009636 | 246 | 106 | 18204 | 5365 |
TNF,SLC7A11,ALB,ABCB1,TXN,BAK1,RDH12,MAP1B,GSTP1,RAB29,INMT,TXNRD1,GPX1,MT3,GPX6,SLC6A1,ESD,AIFM1,RDH11,GSTM2,PRDX6,MT1E,SELENOT,SELENOS,FOS,GSTT1,KDM1A,CDKN1A,DHX15,MPST,GPX3,CCS,MT1M,AKR1A1,HBM,ALOX5AP,TYMS,HBE1,GRIA1,SCN2B,SLC22A8,NEFL,GPX4,MTARC2,CYP1B1,TLR2,HBB,MT2A,TXNRD3,SOD1,CYP1A1,CCL5,MDM2,GSTM3,KCNC1,UBIAD1,TXNDC17,CYGB,TP53INP1,SELENOF,HBA1,BAX,PTGES,PRDX3,NUPR1,SNN,CNP,SOD2,PRDX2,CCL3,COMT,GPX7,PRDX1,SOD3,CDK1,GPX2,LANCL1,MT1X,ABCG2,GLYAT,ATF4,CYP2F1,SLC6A4,PRDX4,CLIC2,NFE2L2,MT1A,HP,SRXN1,MGST3,GSTO2,NQO1,HTRA2,GSTO1,SELENOW,MGST2,SESN2,IPCEF1,GSTA1,SCFD1,GSTK1,GPX5,SLC15A2,CLDN1,EPHX1,TXNRD2 |
| 3.460e-06 | -12.57 | proteasome core complex | cellular component | GO:0005839 | 20 | 16 | 19108 | 5553 |
PSMB2,PSMA2,PSMB11,PSMA3,PSMA1,PSMB1,PSMB9,PSMB7,PSMB5,PSMB3,PSMA5,PSMB4,PSMB6,PSMA4,PSMA6,PSMB10 |
| 3.467e-06 | -12.57 | ATP9A (ATPase phospholipid transporting 9A (putative)) | protein interactions | 10079 | 75 | 40 | 19454 | 5460 |
B4GAT1,ESR2,FHIP1B,VIRMA,RANBP6,STARD3NL,RETREG3,TMEM74,CHRM5,LMBR1L,VAMP3,KCNA2,RIC3,LAMTOR1,SYP,CCR6,RAB11A,TSPAN10,SCN3B,COX6B1,VPS16,TMED7,STX7,LPAR1,SLC15A1,RAB3B,CHCHD2,RAB9A,LPAR2,ATP2B4,TSPAN15,SH3GLB1,CRELD1,STX12,GPR35,RAB4A,RELL2,IFT57,YIPF3,COMMD8 |
| 3.492e-06 | -12.57 | SLC3A2 (solute carrier family 3 member 2) | protein interactions | 6520 | 346 | 136 | 19454 | 5460 |
E2F4,DIPK1A,LGR4,ISG15,RAB4A,CHMP4C,EZH2,RPN1,CYB5B,PLD3,RND3,SLC1A2,TMT1A,COX8A,VDAC1,KRAS,FLOT1,RAB5C,ATG9A,LAMP2,DDRGK1,AGR2,RHOG,ARMC8,HNRNPD,PHB1,DUSP6,FOLR1,RAB35,GJA1,RHOH,DIRAS3,LRRC61,EGLN3,BET1,SLC16A10,CLDN4,RND2,SEC62,CAV2,PIH1D1,CXCR4,DUSP9,RAB5A,EP300,PMAIP1,HSPA8,EYA3,UFL1,TRA2B,STX7,CUL3,RAB11A,MYC,RHOB,LAMTOR1,RIT1,SLC7A11,HSP90AA1,ICAM1,NTRK3,CYB5R3,NFKBIA,LMBR1L,SEC61B,LGALS3,CAVIN2,MAD2L2,GPR37,TP53,FBP1,MAP2K3,NDUFS3,MAP1B,SLC6A3,EMC2,RAB3B,RIGI,DPP4,HDAC6,LAMP3,CD81,COPS5,NPSR1,CRBN,STYK1,MRPS9,HRAS,RAC2,TES,HSD17B11,PRNP,DNAJC1,ASB11,FZR1,ARF6,CAV1,LMAN1,TMPO,STX6,CFTR,CDK7,CDC42,GRM2,METTL14,FGFR1,RPA2,HEXIM1,ARL15,PML,MGAT4B,RPA3,RHOU,RAB9A,LARGE1,CCR4,HSPA5,GSTK1,RAB2A,CSK,DNAJC5,TXNIP,SPOP,UBE2H,ATP1A1,CDC73,MARCHF3,CCNF,VAMP3,PHAX,RHOJ,SLC25A4,VIRMA,GNAI2,SLC7A8,SMURF1 |
| 3.492e-06 | -12.57 | PDK1 (pyruvate dehydrogenase kinase 1) | protein interactions | 5163 | 352 | 138 | 19454 | 5460 |
TRMT11,MRPL13,TACO1,DLST,APLNR,ATP5F1B,AK3,FMC1,ACO2,AUH,MYC,PYCR1,PMPCA,GPR17,CCT2,CIRBP,BLVRA,MRPS25,HADHA,ATPAF2,CXCR4,MRPS7,NDUFS2,HSCB,NPTN,GRPR,NSFL1C,OXCT1,IDH3B,MYH1,NPY2R,PRDX3,TIMM13,ISCU,NDUFAF3,MRPL12,NDUFA5,MRPS18A,ATP5PO,PAK2,ACAA2,GATD3,SSR2,CCT7,TCP1,NDUFV2,MMUT,HMGA1,CLPX,MRPS35,RASSF8,MRPS26,HINT2,HSD17B8,MRPS11,COX8A,PREPL,UQCC2,LSM14A,CCT8,THNSL1,ATP5F1D,KGD4,ETFA,HSDL2,ETFB,NDUFA12,NUDT19,NDUFS6,PDHA1,ACAT1,MRPL53,SUCLG2,AKT1,NDUFAF2,PYCR2,OAT,MRPS16,PRKCB,DLAT,GFM1,RPA3,IDH3A,POLDIP2,TTR,NME4,PDHB,MRPL41,MRPL40,HCST,MRPL10,MTRES1,RPA2,MRPS34,SPRYD4,QRSL1,FGFR1,SSBP1,MRPS9,SDHB,COX4I1,MGME1,ATP5PD,MALSU1,MRPL24,MRPS23,MRPL50,LAMP3,LYPLAL1,KARS1,GRSF1,PYURF,FOXP1,TRMT5,CRBN,MRPS18B,THG1L,HSD17B10,ATP5PF,FASTKD5,ABHD10,PDE12,CD80,MRPS33,ATG4A,THRAP3,PPIF,GLRX5,METTL15,ATP5PB,MRPL47,NDUFA2,CCT5,MRPL49,OTX2,PIK3CA,NDUFS3,ACADSB |
| 3.516e-06 | -12.56 | positive regulation of lymphocyte activation | biological process | GO:0051251 | 328 | 135 | 18204 | 5365 |
EPO,TICAM1,TYROBP,IL15,HMCES,CAV1,MAD2L2,WNT10B,SMARCB1,CD80,CBFB,B2M,CD28,IL23A,BLOC1S3,EXOSC3,CHRNB2,IL7,MEF2C,RUNX1,SOCS5,TLR9,SMARCD3,IL4,ZBTB16,PRKCQ,TACR1,MYD88,CD46,CD81,LILRB4,MIR30B,CD4,MIR21,CD47,PIK3CA,CCL5,ACTL6B,IL12B,SLC7A1,MMP14,IFNG,IL6,IL21,CLEC7A,CSK,IL13,CD86,MIF,PNP,IL18,CD83,ACTL6A,NKAP,SASH3,DHPS,LILRB1,BCL10,HSPD1,CD274,FOXP3,SRC,IL12A,PTPN11,BTN2A2,IL6ST,KLHL25,TLR4,LEP,CD40LG,PELI1,SMARCE1,THY1,JAK2,CCL2,IL5,ICOS,IL2RA,TNFRSF14,CDKN1A,TIRAP,RAG1,IL15RA,BAD,CCL21,CD38,TNFSF13,XBP1,TRAF6,NLRP3,MIR130A,CCL19,EFNB1,AIF1,TGFBR2,CCR2,IL2,DPP4,RHOH,CYRIB,PDCD1LG2,CD209,VSIR,IGF1,ACTB,EP300,IL10,XCL1,IL1A,SLC39A10,KMT5B,SHLD1,FGF10,GPAM,TESPA1,IL2RG,YES1,TOX,TFRC,SELENOK,RPS3,NCK1,PPP3CA,SYK,CD1D,HMGB1,CD40,IL1B,AKT1,BCL6,STAT6,CCR7,DUSP10,AGER,PYCARD |
| 3.521e-06 | -12.56 | negative regulation of cellular component organization | biological process | GO:0051129 | 709 | 264 | 18204 | 5365 |
SNAPIN,MIR210,SWAP70,CAV3,TRIM11,IFNB1,PFDN6,CAV1,CPTP,MAD2L2,SSH3,TNKS,DNAJB6,MIR149,FXN,PSEN1,TNKS2,MTM1,MIR21,MIR30B,DNAJB2,RTN4,HSPA5,GFI1,TNFRSF1B,DNM2,BRCA1,TRIM54,MIR31,SNX3,TMSB10,IER3,FLCN,TOM1L1,CSK,CRYAB,NUPR1,MIR142,CRMP1,ACAA2,CDC42,PYDC2,CDC20,LRRTM1,ZNF207,CST3,SPEF1,ADD2,UBE3A,HNRNPA1,MMP14,EPHA4,THOC2,MIR185,CLIP3,NEUROD2,PRNP,MAP4,GDI2,SLX1A,YWHAH,LILRB1,INPP5K,AURKAIP1,LDLR,GLCE,HNRNPC,PARL,RGMA,PTEN,STXBP1,MAD2L1,PFDN2,BCL2L1,PCSK9,NRP1,RIT2,TMOD2,NR1H2,PAK2,CBLN1,BECN1,PSMG2,SLC35F6,IFRD1,PICALM,AR,SUB1,MIR20A,BUB3,CCL21,PFDN4,MET,LMO4,RPL13A,CTNNA2,SOX9,BAZ1B,TNR,MAP1B,SPC24,BAK1,RAB29,SEC22B,ADD1,GPX1,MIR9-1,MT3,VDAC2,SVIP,IGF1,EP300,BOK,PIP4P2,PACSIN3,MIR92B,SNX33,SEMA5A,SLC25A31,SMAD4,ADTRP,TOM1L2,FAM107A,PPP3CA,WASL,GCLC,TRIM37,LMNA,DYRK1A,TMEM182,IL1B,SPP1,AKT1,TBC1D4,SPOCK1,DKK1,NOP53,B2M,VEGFA,CAPG,ADCK1,CAPZA2,LGALS3,RAD21,MKKS,APOC2,NDC80,PRELID1,IKBKB,SCFD1,PPARG,TFIP11,STMN2,NBN,PAQR3,CSNK1A1,CTNNBIP1,PTGER4,F11R,DCP2,TMOD1,PIK3R1,KLHL22,TSPO,MAPRE1,NEO1,SOST,ROCK1,USP30,LPAR1,CD47,PIK3CA,MDM2,SDCBP,PAFAH1B1,PFDN1,CAMSAP2,TP53,NLGN1,SPTAN1,BMERB1,LCMT1,HUWE1,CRBN,TMEM14A,CEP97,RNF41,DLG4,PMP22,EPS8,THY1,GHITM,MTMR2,RAD1,ITGAV,MGARP,SMARCA5,SCAMP5,HSPA8,SRC,IL15RA,TESK1,FGF13,IK,SLC25A5,WDR44,ZNF365,PHF23,PSMD10,CXCL10,ATG3,TMSB4X,TMEM39A,MIR105-1,PICK1,DPP4,ARF6,FEZ1,PPIF,PLSCR1,CYRIB,XRCC5,MIR214,MIR17,CD38,FKBP4,MYLIP,CCNF,TLR2,MIR145,TMOD3,TRIM32,SLC25A4,BIRC2,TFRC,LRRTM2,MID1IP1,TNF,ADIPOQ,SPTBN1,ROCK2,DUSP22,MUL1,STN1,CAPZA1,RAF1,CERS2,FCGR2B,HDAC6,TRIM46,MIR98,EMILIN1,STAP1,ABHD17A,CLU,CORO1C,CH25H,MIR205,HMGB1,MINAR1,CDK5,ARFGEF1,NUF2,PFDN5 |
| 3.525e-06 | -12.56 | post-translational protein modification | biological process | GO:0043687 | 858 | 313 | 18204 | 5365 |
RNF11,RING1,CTNNB1,TNFAIP3,TRIM8,OTUD7B,RNF208,COPS7B,UCHL3,TTL,RNF39,KLHL12,PPP1R11,FEM1C,UBE2W,DCAF11,RNF103,KLHL15,RLIM,NEDD8,FBXO9,WDR77,UBA52,MARCHF3,RPS27A,ISG15,RNF8,RNF128,MARCHF9,ASB3,RNF167,UBE2F,UBE2G2,HERC4,UBE2V2,USP13,MSL2,TRIM37,UBE2V1,KBTBD2,SIAH2,FAM20C,FEM1B,AKT1,DCAF16,PRKCB,FN3KRP,SYVN1,CDK5RAP3,VIPAS39,CTU1,RNF126,SUMO1,COPS5,USP14,JAK2,ZBED1,MED31,E4F1,OS9,PRPF19,ANAPC11,USP46,CAND1,OTULINL,TRIM63,SKP1,UBE2M,TOPORS,DESI2,WDSUB1,ATG4C,DCAF5,MARCHF4,TRIM24,UBE2D1,UBE2N,TRIM22,BAZ1B,CBL,SPSB1,PCMTD1,ANAPC4,FBXO32,KBTBD13,TRAF3IP2,USP2,STAMBP,COPS7A,USP38,FBXO11,RCHY1,UBB,SOCS2,CDC20,FZR1,KLHL7,DCAF4,RNF14,UBE3A,WWP2,UBE2K,UBE2E2,CDC16,BRAP,TRIM68,NEUROD2,MED21,RNF181,MAP3K12,USP15,WSB1,SOCS4,UBE2A,KLHL25,TRAF7,RNF34,PELI1,COPS2,HECTD3,TRIM34,RNF122,MARCHF5,RPS6KA4,HERC3,PELI3,SHPRH,CBFB,OTUD6B,RNF7,VPS18,BAP1,USP5,FBXO25,STAMBPL1,MED27,TRIM11,IFI27,SOCS3,URM1,RC3H2,NMI,USP8,NEURL2,TNKS,ANAPC2,KLHL24,UBE2I,TNKS2,EGR2,TRIM26,UBE2S,RNF113A,SOCS5,SMURF1,UBA3,SPOP,KLHL3,IFIH1,ATG7,COPS4,UBE2B,BRCA1,TRIM54,ZBTB16,WWP1,TRAF2,FBXO31,UBE2L3,TRAF1,TRIM32,CDK8,TRIM6,SENP8,BIRC2,ELOC,ASB1,KBTBD6,IRF2BP1,TRIM62,ATG16L1,APPBP2,DCUN1D5,ATG4A,DDRGK1,NT5C2,PARP2,MUL1,KCTD10,HDAC6,HECW1,RNF5,RNF182,MED11,FBXW7,TRIM5,BFAR,STUB1,KCTD11,FEM1A,MED30,OTULIN,STX1A,ANAPC13,CISH,MED10,KLHL9,FBXW11,RAG1,SPATA2,RNF152,DCUN1D3,RNF141,TRIM23,TNFAIP1,UBE2E3,DCUN1D1,IRF2BPL,ATG3,USP16,PML,PIAS1,RNF10,RNF133,FBXO3,RNF40,OTUD6A,UFM1,RNF26,PSMD14,TPST1,RNF144B,PRKCA,NAE1,KCTD9,NDP,TRAF6,MYLIP,CCNF,TRIM45,ZNF451,UBE2D3,SENP5,USP30,ANAPC16,SPOPL,DTL,RNF146,MDM2,FBXL3,CDC26,RNF121,MED17,SUMO3,ZC4H2,LCMT1,CDC23,VCPIP1,ANKIB1,FBXO30,HUWE1,CRBN,CBLL1,ENC1,RAB40AL,PARP11,TRIM27,RNF41,FBXL7,TRIM21,TRIM35,G2E3,SUMO2,ASB11,LARGE1,FBXO22,CCAR1,SPSB3,RNF115,HINT1,UBE2H,NFE2L2,FBXO7,NSMCE3,RNF139,CUL2,DET1,TRIM44,SIAH1,TRIM15,RBCK1,AREL1,UFL1,ASB8,DESI1,STT3A,NBN,JOSD1,CCNA2,TRIM52,CUL3,COP1,CDCA3,TRIM10,KLHL22,UBR7,HECTD1,ZNRF1,NQO1,RNF20,TRIM3,RNF187,ASB7 |
| 3.526e-06 | -12.56 | regulation of cellular response to growth factor stimulus | biological process | GO:0090287 | 374 | 151 | 18204 | 5365 |
CXCL13,MIR296,MIR149,NIBAN2,MIR503,PPARG,MSX2,FZD4,TMEM204,MIR21,MIR30B,FGFBP1,SFRP4,MIR146A,MIR100,LDLRAD4,SMURF1,HSPA5,ELAPOR2,NREP,MIR342,SMAD2,BRMS1,MIR106A,IL4,NPTN,MIR195,LEMD3,MIR210,HSP90AB1,MIRLET7G,VEGFA,ING2,CAV3,DKK3,HHIP,SIN3A,FSTL1,TGFB1I1,MIR204,DSTYK,BCL9,MIR10A,SPRY1,USP15,MIR140,PPARA,VEGFC,CER1,OTX2,PBLD,PTPN1,IL12A,FAM89B,APLN,MIR1224,MIR885,TNFAIP6,ZNF451,NEO1,SOST,MIR1-1,FLCN,SFRP1,MIR302B,PTP4A3,MIR490,MIR15A,UBE2D3,MIR142,SDCBP,CASK,IL17F,PEG10,DOK5,DLX1,TP53,IL12B,FKBP8,MIRLET7B,UBE2D1,MIR497,CHST11,MIR20A,MIR17,MIR214,HTRA1,MIR373,EID2,SAP30L,ILK,PRKCB,MIR16-1,HGS,MIR424,RGMA,CITED1,MIR10B,GREM2,MIR200C,FOLR1,ATP2B4,FKBP1A,FGF1,MIR573,SOSTDC1,NRP1,CAV2,PELO,EMILIN1,MIR98,NOG,ZDHHC17,STK11,MIR361,CREBBP,GREM1,GPC1,CHRDL1,SMAD4,GRB10,FGF16,STUB1,DKK1,CTDSPL2,IL1B,FAM20C,TGFB3,RBBP4,FGF10,CTNNB1,TMEM108,MSX1,MIR145,MT3,SHISA2,SPRED2,CYFIP2,MIR9-1,ING1,TWSG1,NOTCH2,SAP30,EP300,SPRED1,RBBP7,BRMS1L,MIR101-1,SMAD3,CD63,RBPJ |
| 3.560e-06 | -12.55 | RAC1 (Rac family small GTPase 1) | protein interactions | 5879 | 1005 | 346 | 19454 | 5460 |
EHD4,DLG1,EMC2,HSD17B10,SNAP23,HSPE1,TOM1,VWF,CTNND1,CCDC47,SLC29A1,EEF1A1,LBR,ZDHHC8,KRIT1,CASK,SRPRA,HACD3,EHBP1,C2CD2,CDCA3,CAV1,RELL1,HDAC6,RAB23,ARL2BP,SLC2A1,ESYT1,TIAM1,OPHN1,ITGA2,B2M,IL1RAP,HMGB1,TMEM209,BRINP1,SNRPN,CNP,PAK5,JUP,OXSR1,OPTN,VAMP3,YES1,SLC25A4,SH3BP4,PYCR2,DEPDC1B,KPNA6,PPP1CC,XPOT,EPHA2,SLC39A7,JAK1,CHN2,DMPK,MARCKSL1,E2F4,LGR4,STIM1,VAMP2,CFAP36,WDR6,PHB1,XPO5,IGBP1,GJA1,SOSTDC1,OCRL,SPTAN1,ERLIN1,RAB11B,TAF7,WDR11,RHOG,CXCR4,POLA2,WASF3,ETF1,VAV2,MYL6,NDUFA5,RAN,CYB5R3,CLDN3,AP2M1,FZD6,CHCHD3,PARL,TOMM40,RHEB,ELMO2,MYO6,LMNB1,PFDN6,RIT1,PALM2AKAP2,SLC25A11,ABCE1,RPL3,SLC16A1,SRPRB,KPNA2,TOLLIP,SLC6A8,SNAP29,MTCH2,IPO8,ARHGAP12,TFRC,BMPR2,STT3A,COX4I1,ARL6IP5,FCHO2,TMPO,ARHGEF6,TLR2,RAB9A,SPTBN1,SDCBP,RPA2,GSTP1,GIT2,PARD6A,UBE2M,PRKCA,QSER1,STX10,ROCK1,SRC,SLC6A6,RAP2C,ATP1A1,EFNB1,KRAS,ARHGAP15,ARL4A,SOX2,KDELR1,EED,CORO1C,UQCRH,VAMP7,MDFI,PPFIBP1,TBC1D5,HSPB1,HSPA8,EMC1,STAU1,SSR3,GNB4,YIPF5,CNPY3,SDC2,PAK2,FDFT1,FAM83B,BST2,ATP6AP2,EPS8,LAMTOR1,SPCS3,SLC38A1,RAB1A,SFXN1,GARRE1,HUWE1,CDC42SE1,RIGI,ADD2,CMPK1,FAM13B,ALPL,ITGB8,FAM169A,DHRS7B,PTPN1,DLGAP4,IL18,ATP1B1,DAG1,CDC42SE2,POR,NME2,OSBPL8,DVL2,INPPL1,RPA3,NDUFC2,SLC7A1,YKT6,NF2,PIK3R2,CDC42EP4,PDE8A,SEC22B,ARHGAP1,PIP5K1A,ADIPOR1,COX6C,CTDSP1,SLC12A2,STOM,PICALM,MET,AGAP1,GAB1,METAP2,TUBA1B,EIF2AK2,CTNNA1,SLC11A2,COPE,RHOJ,FERMT2,UBB,GNAI2,AGAP2,RACGAP1,MAP3K11,PRPSAP1,TNF,RPS27A,IMMP2L,AHCYL1,GOLGA7,FLOT1,RAF1,RPL29,FAF2,IFNGR1,RPN1,PRKAG1,PCDH17,NME1,ITGB5,EGLN3,PPIA,TMEM237,PIK3R1,RAB32,SLC20A1,BIRC2,HSCB,CYFIP2,STX7,DAAM1,NOTCH2,ELFN2,VAPB,FAM91A1,LRRC8A,ACTB,NIBAN2,PKP4,RAB11A,YWHAZ,RHOB,SLC7A11,SCFD1,HTRA2,ILK,MYD88,AKAP12,H3C1,CSE1L,STRBP,PIK3CA,EXOC3,CCM2,ITGA6,ADD1,RAP1B,SLC39A10,FLRT2,RAC2,VTI1B,SLC38A2,STX6,LMAN1,COX5A,SLITRK5,KPNA1,BAP1,LRP10,DERL1,FTSJ1,CLDND1,CDC42,SSR1,CSNK1G3,LEMD3,NECTIN2,TRAF7,RGL2,AKT1,SLC25A1,RAB2A,ARHGAP21,GORASP2,ATP1B3,UBE2H,CYP1B1,GNA11,CDK5,ROCK2,SLC20A2,PAK6,PRPS1,EEF2,RAB35,SWAP70,RAB1B,DDX50,PTDSS1,WWP2,RAB5C,OLR1,YWHAG,XPO1,CTNNB1,ARHGAP5,NCK1,CDC23,NDUFS2,PHB2,ITGAV,PACSIN3,ABCC5,USP6NL,IL6ST,MAP2K1,LACC1,CSNK1A1,RRAS2,STAT1,NCKAP1,ESR2,PRMT6,SLC1A3,STX16,SLCO3A1,H2AZ2,PDF |
| 3.570e-06 | -12.54 | regulation of nitric oxide metabolic process | biological process | GO:0080164 | 65 | 37 | 18204 | 5365 |
CLEC7A,CD36,CX3CR1,HSP90AB1,TMEM106A,SOD2,DYNLL1,CAV1,TNF,JAK2,TICAM1,CD47,NOSIP,ATP2B4,IFNG,IL10,ROCK2,ACP5,SMAD3,TLR6,MIR212,HSP90AA1,DDAH2,HBB,KLF4,SELENOS,TLR4,DDAH1,RGN,TSPO,MIR99B,NOS1AP,CLU,IL1B,GCHFR,MIR132,AKT1 |
| 3.577e-06 | -12.54 | GRB7 (growth factor receptor bound protein 7) | protein interactions | 2886 | 177 | 78 | 19454 | 5460 |
TRIM36,LUC7L3,ACACA,AGAP1,RARS1,EIF4B,MET,MRPS34,MRPS7,BRIX1,G3BP2,STAU1,RPL4,PDHB,MTDH,HSPA8,RFC4,RPL27,MCAT,AP2A1,AR,PPP1CC,RACGAP1,RPL39,RIOK2,STAC3,SFN,RPF2,TNPO3,RPL10,RPL19,RPL10L,RPP25L,RPL35,RPL13A,MRPS21,ATP5F1B,RPL37A,PHAX,TMSB4X,RPL18,RPN1,RPL15,ZNHIT1,MSH6,HNRNPDL,FARSA,ZBTB16,DYNC1I1,KIT,RPL23A,PICK1,RPL31,RPS2,MRPS26,HNRNPD,SHC1,MAP3K14,PPIL4,MRPS35,RIOX2,RPL6,USP2,TLE1,PSMD3,PRPF19,CAV1,CCT7,DHX15,TOP1,RPL35A,RPLP1,HP1BP3,CORO1C,POLR2L,RPL32,SRP14,RPL12 |
| 3.577e-06 | -12.54 | VAMP2 (vesicle associated membrane protein 2) | protein interactions | 6844 | 177 | 78 | 19454 | 5460 |
RAB2A,RAB11A,SCN3B,SLC30A5,SLC6A4,DNAJC5,LAMTOR1,SYP,RHOB,TDP1,NAPA,SCFD1,VAMP3,RPS12,LGALS3,LAMTOR3,SEC22B,UBA52,SEC62,CDC42,LMNA,VAPB,ACAA2,UBE2M,JAGN1,PRKD3,RABAC1,HSPA8,RAB9A,TMEM185A,RAB5A,NAPG,LPAR1,STX7,ABCC2,TAX1BP3,LAMP2,DPP4,RAB5C,LAMP3,RHOG,STX1A,RAB35,HRAS,HSD17B11,GJA1,RAC2,ARF6,SNAP25,STX6,DIRAS3,CAV1,RAB11B,SNAP29,CENPM,TMEM101,MAP1LC3B,DDX39A,TMEM31,TFRC,EXOC3,RAB4A,STX12,HGS,STX8,SYPL1,TMT1A,COX8A,SNAP23,HUWE1,KRAS,SLC7A14,RAB3B,STX11,FKBP2,VAMP8,CPLX1,FLOT1 |
| 3.595e-06 | -12.54 | USP30 (ubiquitin specific peptidase 30) | protein interactions | 84749 | 106 | 52 | 19454 | 5460 |
PTPN1,AIFM1,CCAR2,TOMM70,PLGRKT,COX14,MARCHF5,RAB5C,SLC25A46,NOL4,CTNNB1,HAX1,PEX3,SFXN1,CLPB,KRAS,FKBP8,IMMP2L,MTCH2,CLEC2B,TIMM8A,PTRH2,C1QC,RMDN3,MGST3,UBB,ESR2,MYC,MTG2,SCN3B,CUL3,TOMM40,RFTN2,FIS1,BAX,NLRP3,HTRA2,CXCR4,EXD2,AKAP1,MAVS,SLC31A1,HSCB,GRPR,SLC25A51,PHB2,TOMM20,PXMP2,SF3A1,TOMM22,MTX2,HCST |
| 3.602e-06 | -12.53 | cellular response to stimulus | biological process | GO:0051716 | 6307 | 1991 | 18204 | 5365 |
IL1RAP,EPHB6,ARHGAP12,TBC1D24,ITGB8,HINFP,FBP1,BCL6,RHOU,RAB11B,HFE,ELMO1,TOPBP1,HSH2D,TOP2B,DDAH1,RUVBL1,PDIA3,PDE12,EDA2R,SEC13,AVPR1B,ATP1A1,TMUB1,XCL1,RBPJ,TWSG1,FGF3,CYP11B2,ACTB,HMGA1,TNF,SHMT1,MAPKAPK3,AIF1,FOXC2,TIFA,CNTN1,CEBPG,GJA1,CXCR3,MIR17,CKLF,OLFML3,MRGPRX1,CYP11B1,TBC1D10C,CALML5,IK,LRRC8D,CITED1,RB1,GREM2,OR52M1,SLC25A5,GPHA2,PTGER1,GPR83,RAB31,TMSB4X,CDK9,NDN,FOLR1,TLR4,MPP1,APLNR,LRRC28,OR5L1,KLF4,ZBED3,HOMER1,INPP4A,LAMB2,LARGE1,BRINP2,GHR,RAP2C,OR4M1,MSMP,ITGAV,GABBR1,ARHGAP1,MGMT,UGT1A1,CRABP2,TRIP4,TMEM38B,PCGF2,RAD1,LEPR,NEK7,SOD2,MCM4,ASCC1,TNFAIP6,SOST,SYNJ2BP,MAP3K3,PPP1R1A,VCPIP1,STK4,GNAI3,MAEL,BRINP1,TNFSF10,SGTA,EPCAM,AOX1,FCMR,SLC16A1,MIR212,NREP,SUV39H1,GSTA1,PPP2R1A,IRAK4,SUFU,CHMP5,RHOG,NQO1,HELLS,KLHL22,CD3G,IMPACT,EIF2B2,ATAT1,IPO8,GABARAPL1,B2M,RBCK1,SIAH1,CBR3,RNF139,MIR638,ZNF668,HMCES,HINT1,CST11,PPY,SLC31A1,CXCL1,RNF167,SULT1A3,OSER1,CCR6,ISG15,RPA3,SDF2L1,DHX9,SPP1,BTBD10,MSL2,RMI1,OR14J1,COL3A1,TLE1,KCNMB1,EIF2B3,TRIM8,IL18BP,DEFB1,LTB,GABRG2,RAB29,MIR370,HRH2,PDE1A,DNAJB9,RAB13,IGBP1,UBXN10,CHST11,DLG1,BECN1,TOPORS,FIS1,HBB,FMOD,OR4K13,CCR5,MCHR2,STAT2,IL1R2,FCGR1A,IGFBP4,TAS2R40,OR4N4,MAP3K14,MAP2K1,HDAC5,PPP1CC,PRMT2,HGS,KCNIP2,CCS,GNA14,NXPH3,KDM1A,OS9,GAD2,SKAP2,SLC38A9,RGMB,OR51E2,IL5,RASGRP2,TLR7,BTN2A2,CSF2,IL6ST,CDNF,STX8,SCG2,MAP1LC3B,LILRB1,CNTFR,FRZB,ID1,YWHAH,RAB18,ATP5F1A,CCL3,PPIA,CDC42,PLA2G4B,RCHY1,PTGER2,TIMP3,IFT172,FERMT2,FBXO32,CSNK1E,IGF1R,SFRP1,EPHA4,MIR200A,DEFB124,IL2RB,RAB4A,PELP1,EFNA3,KCNC1,TULP3,NUDT1,TCP11L2,CD81,AQP3,MIR149,EPHX1,IGFBP3,MYD88,TRIM54,OPHN1,HTRA2,GPR162,IL20RB,SOCS5,HSPA5,STAMBPL1,GSTA4,CDKN2AIP,PLCXD3,DEPDC1B,SHC3,MAVS,FURIN,THG1L,DOK4,EEF1E1,TYROBP,CLIC2,OR9I1,STK11,CREB3,CCAR2,FOXA3,POLDIP2,NME2,RGL2,SGF29,TAS2R7,HDAC6,SCG5,SAV1,ACVR1B,DERL2,TMBIM6,OR4K1,CD40,CH25H,NR1I3,PRKAB1,ASB1,YES1,BIRC2,DUSP1,CMTM7,SLC23A2,LACRT,EGLN3,ASIC1,GLUL,PARP2,CD2,LHB,SLC2A1,OR5K1,VIP,STAT5A,CDC42EP3,PPIF,NPTX1,PTHLH,HCAR1,PICK1,P2RY11,RNF10,CSNK1A1L,FRS3,TLR2,MIR183,GLRB,CYP1B1,FKBP4,OR7D4,HBE1,CTNND1,CLEC12B,DUSP9,TMEM231,OPRL1,CACNB4,CHRM3,MIR16-1,PIGA,DRD1,MAPKAPK5,NUP62,WBP2,HPGDS,NGB,MAP2K6,CLCN6,IL2RA,NHERF1,H2AC25,SYP,VAC14,PIK3CG,INSIG2,FASLG,GNB4,ABCG2,CNIH1,ELK3,TAS1R2,WRAP53,GTF2H2,IL18,CAMP,MIR143,PDCD4,OARD1,STAU1,NDUFS2,PAFAH1B1,IFT52,NLE1,WDR12,TIAM1,RASGRP3,OSGIN2,GARRE1,GORASP2,OR8B4,OR7E24,MIR493,SLC52A3,OPRK1,ASB8,IPCEF1,CCDC47,NR2E1,PIK3R1,RAN,CUL3,RLN3,SSRP1,SBK2,RAPGEF5,LAMTOR2,NF2,SLC38A2,RGS6,MIR455,SIT1,BCL9,RCE1,ARHGEF6,TLR1,ABHD2,OR4A47,IL15,B9D1,RTF2,IFNA13,TLR6,AGR2,AKT1,KCND2,DYRK1B,OR4N5,IL1B,CLEC1A,ESD,KBTBD2,RANBP1,MIR182,ELAVL4,ITGB5,PPP3CA,FAM107A,MT3,NPVF,CCND3,RETN,GH1,TNFAIP3,AGTRAP,TXN,GSTP1,GID8,ABCB1,TTR,NSG1,CALR,SKIC8,IGF1,APH1A,ROMO1,UBE2W,UCP2,KLRD1,RND2,SUSD6,PSMG2,PHF1,MSH6,TGFBR2,FAS,SLCO2B1,KIT,FLRT3,SIVA1,UTS2,MIR320A,EIF4A2,CPE,MET,TOLLIP,MIR448,CDK5RAP3,SYVN1,TMEM88,EGLN2,PAXX,NR1H2,PPP5C,CDC42SE1,SLX1A,GNG5,CXCL14,OR2AT4,DAPK3,OXSR1,PRNP,CARHSP1,MPV17,TMED1,ERRFI1,AKT2,VPS26B,COPS2,PLXNC1,MMP9,CD86,ACAA2,IFNA10,GNAQ,OR5AP2,ADIPOR2,TRAF3IP2,BAX,IL6,MOB3B,LAMP2,CHRM4,TOM1L1,OR51A4,DDX1,FCER1G,KPNA1,ERLIN2,SLC2A8,DNTT,MIR223,ACVR1C,G3BP2,DNAJB2,IFNA2,CDC73,FABP4,DNAJC3,GRIA2,SELENON,OCRL,SLC39A9,MGST2,PPP2R5A,MCL1,TLR9,PLCB1,PTH2,KCNIP3,TNFRSF1B,ADM2,UTS2R,CMKLR2,GNL1,UCN,LPAR2,ANXA4,CD80,ZBTB33,CLEC6A,MGME1,EDNRA,NMI,GPR65,GMDS,MAD2L2,ADSS2,OR2W1,HRAS,PYCARD,GPR78,CD226,BCCIP,TMEM198,OR2H2,CXCR4,GTPBP1,CXCR1,PTK7,MPIG6B,RGS2,HMGB1,BCL7B,GABRB3,GPX6,MBL2,PRKX,PPP1R1B,LY96,TRAF1,RFC5,MSX1,PAQR8,MIR145,CX3CR1,CCM2,CACNB3,RAF1,IL10,PTGFR,MAP3K11,DDRGK1,ZC3H15,RBBP7,HSD17B1,TMEM126A,CACYBP,CCR2,F2,EDEM2,ACVR1,RAD23B,PRKCA,NEFL,CGAS,DAP,VIPR1,ADNP,CTTN,TAS2R46,STRADB,ASIC2,OR4D11,GUCY1B1,GPX3,TRA2B,SH3GLB1,GLRA2,HSP90B1,RFC4,USP16,INPPL1,VAMP2,POLE3,EYA3,DDIT3,OR4N2,DCLRE1C,CCL8,NKIRAS1,FGF22,ADORA1,ADORA3,PLPP4,P2RY1,NKAP,TSHR,RAC2,PRDX2,PSENEN,COMT,ARHGAP21,OR4D2,UBE2D3,CYGB,OR8B12,ITGA6,GPR173,AZI2,CLIC4,ERCC3,RRAS2,FKBP8,CCNY,CXCL8,LPAR1,MRGPRX4,ABCC5,RGS1,RRAGA,MIR30A,PPARG,KCNK10,SLA2,PRKCQ,SESN2,PGR,GABARAPL2,GAB1,UFD1,MIR193A,RABIF,F11R,GSTO2,CHRNA7,EZH2,IL3,NCSTN,NFYB,MIRLET7G,CHCHD4,EGR1,IL34,IKBKB,OR2Y1,MKKS,FANCG,NR4A2,CUL2,MNAT1,EPO,SRP54,CCL20,CREBBP,TNFSF18,DDIT4,GSTM2,ATP6V1G1,GCLC,ADAMTS1,TF,NUDT2,IL2RG,DRG2,NCK1,TWNK,FGF10,RIT1,SPC24,IL1A,GTF2H5,KRAS,OR10G9,ATP1A2,LITAF,PTTG1,OR2D3,ADAMTS20,PDAP1,MTF1,OGN,FEN1,AIP,ARHGAP25,SUMO1,RNF126,OR8K1,DIRAS3,OAS1,CRHR1,LTA,FOSL2,LRP12,MAP1LC3A,ACTN4,OR6C4,CAV2,MIR200C,SMAD1,CHRM1,IRF7,NLRP6,GLYAT,GDI2,TNFSF8,UBE2A,CHRM5,NFIL3,SRM,CDK1,HTR1F,OR4K2,RPS6KA4,KCNJ2,CYP26A1,DAPK1,FAF2,ZSWIM7,SEMA6C,CDC20,HSPB1,TDP1,LY6H,MYC,MIR126,GLRA1,SOS2,DLX1,HCRT,GSTM3,FAAP100,MIR106B,RNF113A,CD4,PTN,MTM1,GPR22,PSEN1,TNKS2,OR4F6,ATP1A3,MIR324,FAM83B,CLDN1,IDE,MIR342,SMAD2,BRCA1,SLC38A3,SERPINB6,MIR31,RBM22,OR10A4,GABRB2,CYP2D6,IRF9,OR6M1,ZYX,CDKN2D,OR10G7,BLOC1S3,CDIP1,RBFOX2,TNKS,TAB1,PPP1CB,ADGRL3,PRDX4,MCOLN1,RBBP8,SOCS3,CAV1,IFNB1,ADIPOR1,STK38,NKX3-1,NFKBIL1,OR4S2,CISH,OTULIN,CCL23,RPL3,RINT1,CLU,GPR85,GNB1,TMIGD1,TEX264,OR13A1,CLTRN,TFRC,POLD2,PIK3AP1,RAP1A,KCNJ10,STC1,ALKAL1,NR2F6,LMBR1L,SARM1,NINJ1,CTLA4,UMPS,RAB35,GRM2,SFTPD,TLR5,GADD45A,NDP,TLR10,CD2AP,LAMTOR1,CD38,GSKIP,PLN,ZDHHC16,FGF13,ALOX5AP,GNA11,SRI,IL15RA,EIF2S1,TERT,CRADD,CHN2,OR4D9,PML,BMPR1B,GSTT1,HCLS1,DISC1,EPS8,KRIT1,WIF1,MCM3,SQSTM1,LEP,RAB40AL,PHB2,SLC25A23,DAG1,SH3BP4,CALY,SMARCA5,GNG2,TNFSF12,MGARP,KCNJ11,SST,CMBL,FAM162A,OR5B3,DOK5,SNX10,PLCL1,GNB1L,ARHGAP5,RNF146,RFXANK,EIF2B5,NTRK3,TLR8,TOMM7,TAAR1,GSTO1,PDIA6,UBASH3B,LPXN,SMUG1,LILRA1,TMEM199,SEMA7A,BMPR1A,IVNS1ABP,MT1A,TCP11L1,PRMT6,AKR1C2,NFE2L2,ASB3,SEMA3C,ARHGAP15,SMAD4,INO80E,MAPK4,PDIA2,GPR146,PYCR2,NOP53,TNFSF15,NDNF,UBE2V1,P2RY4,UBE2G2,BRS3,GPT,RALA,CTNNB1,CYP2R1,SLC1A1,MIR95,HYAL2,SHLD1,PRKD3,CD164,KARS1,PDCD10,SLC8A1,UBE2N,CARTPT,RRN3,NCOA5,CYP2C8,TXNRD3,SS18,MIR221,ATP5IF1,STK26,CD14,EIF2AK2,POLL,IL22,GNAI2,SEC61B,RLN2,HPF1,TNFSF13,CREBZF,CDC42EP2,GRIA1,DEFB114,UGCG,CD34,SMCHD1,ACACA,TUBA1A,DVL2,HBM,LACC1,ASF1A,CRY1,USP3,VLDLR,STAT1,IRAK1BP1,LRP6,MORF4L1,PTEN,JAK2,PPARA,RXRG,IFNGR1,VEGFC,TRAF7,PAK5,GPC4,LANCL1,PPP4C,GRM1,NEUROD2,ADRB1,LDLR,DMAP1,GRIK1,JUNB,PRL,CD79B,TOP3B,SPG21,STAMBP,CSK,ALCAM,BRAP,PDE6A,FGR,YWHAG,NPBWR1,FGFBP1,MIR21,CXCL3,CPNE1,SYNCRIP,UBE2B,JAK1,HACD3,CREBL2,GUK1,PCK2,SLCO1A2,MOB3C,DNM2,GNRHR2,SMURF1,NPB,GNAZ,LIG3,KCNH1,LDOC1,PMAIP1,CD36,SERPINB9,MLH3,NEURL2,OR4Q3,ADCY3,IFI27,GPR15,DUSP10,CHRDL1,KDM2A,MIR98,PCLAF,OR8G5,RNF5,CXCL12,CDK5,FGF7,DNAJC10,STUB1,CYP4F12,CYP3A5,RPA2,ERLEC1,PHB1,ANP32A,TEX12,FCGR2A,RDH12,CX3CL1,GINS4,MUL1,GRM8,VAPB,EXD2,PDCD1LG2,CSNK2B,TENM3,NHEJ1,TAS2R16,FUT8,NLRP3,CCL25,CASTOR2,KCTD9,PPM1D,YWHAB,RGL1,MIR214,SLC22A12,GNG7,NUP35,NPY5R,EID2,CASP4,CCL18,RNF152,ILK,LRAT,MIR105-1,CDKN1A,LSM14A,ALKBH3,IFI6,CYB5B,CER1,DLG4,CLCA1,TAS2R5,PTPN1,LILRA3,PPIB,HSPA8,ACKR3,TMEM33,RAB30,TIMP4,DDX5,OR10A7,POR,NRGN,HPCA,GNGT2,MIR1-1,HTR5A,OR8B8,RCVRN,TP53,SDCBP,UBIAD1,MPG,MDM2,TAC1,TP53TG5,CAP2,DAAM1,CD247,CXCL13,UFL1,CHMP4C,ASB7,HOMER3,S100A6,MLC1,CDKN1B,FAF1,CYP2C18,LGALS3,HAND2,MCM8,SRSF7,ELMO2,ADRB2,SEMA5A,RNF8,STAT6,CCR7,MAT2A,FAM8A1,DKK1,GLRX2,RFC2,CXCR6,SH3BP5L,JAGN1,SESN3,ADD1,GJB2,AANAT,MAP2K3,ZFAND2A,KLHL15,TMUB2,DPEP1,ALB,CD209,CYP1A1,BRINP3,SNAI2,EFNB1,LTBR,LRRC8C,BAG3,S1PR4,ERO1A,RHEB,SOX9,CBL,PTPN5,GHRL,CSNK2A1,CPEB1,PROK1,REG1A,NUCKS1,SYNGR1,MRC1,CCR1,IRF8,CPNE2,CDC5L,STOML3,NR1I2,CTSB,PRPF19,ING5,CD200R1,GRAP,EIF4EBP2,RNF34,SETD7,OPRM1,STK3,CFL1,PDE7A,IRF3,HEY2,MAP3K12,BCL10,REN,IL12A,SHPRH,SOD3,RAB9A,MIF,HNF1B,FZR1,NUPR1,CRYAB,SOCS2,DUSP19,CCL17,PPP2R5E,GGCT,FLCN,TLR3,DYRK2,AKAP12,UBAC2,RORB,CCL5,KCNB1,RGS19,TXNRD2,MIR146A,DGCR8,FXN,CCDC186,TACR1,OR5I1,GTF2H4,IL4,MDC1,GPR35,ING2,EFNA5,GSTA2,DKK3,RUVBL2,CMA1,CCL27,CSNK1G3,SELENOT,PRDX6,FBXW7,OR4K17,PRR5L,TESC,S100A8,NOG,RASL10A,NUF2,RAB14,HILPDA,FGF16,SYK,NPY1R,NLRP1,OMG,CCR4,FAM83A,RAB33A,GPR171,RAB33B,RHOBTB1,RASD1,UBE2L3,OR1M1,DCUN1D5,TBK1,CYRIB,XRCC5,CDK4,MIR32,VAMP3,DIRAS1,PIAS1,VPS54,RARRES2,G6PD,RAB5A,SLC12A2,DMPK,GPR75,GNG12,LRRC40,ARL6,KIN,ARL2BP,PDE2A,NPPC,NPSR1,IGF2BP1,DUSP6,CHCHD2,CCL2,TFEB,MIR140,PDE4B,THY1,RNF41,CD40LG,HIKESHI,MACO1,CD58,BACE1,ASB11,OLFM2,GPX7,LAMTOR3,PRDX1,RB1CC1,CSH1,KLF3,MIR15A,ROCK1,THOC1,P2RY12,MAP3K21,ICAM1,NPY2R,RGS7BP,NLGN1,APEX1,TCIM,RASSF4,NTF4,IL17F,SLC13A5,PIK3CA,CD47,BEX3,LMBRD2,CAMK1,RXFP2,DEK,FZD4,CAPN2,TERB2,PRKACB,AMIGO1,OSM,YWHAZ,CCL1,WDR19,KLF1,VKORC1L1,PIK3R2,TIMP1,SAMHD1,MGST3,IL23A,ALKBH2,VRK1,OR9K2,VEGFA,MTPN,FGF23,RRM1,ALPL,PDE1B,NSMCE3,RPL26,ITGA2,FKRP,NCR3,NYAP2,BMP1,AIFM1,DELE1,GNRH2,OR4E2,TGFB3,SIAH2,CEBPE,WNT7A,NPY,CXCL11,KICS2,OXTR,TXNRD1,RGS5,BAK1,MAP1B,VDR,OR10Q1,GNG3,MRGPRX3,TAX1BP3,GPR34,GRPR,FAM83C,SIRT7,NFKBIA,LPAR6,SOD1,AR,FCAR,LAT2,CNR1,CCND1,CYTL1,PAK2,TRIM63,IL2,MIRLET7B,SLCO1B3,PID1,RPL13A,INSYN2B,XBP1,CD59,BUB3,TERC,KRT8,RGMA,ATF1,LCP1,PRKCE,FGF1,MIR187,PCSK9,NRP1,GNB3,CCL28,PPP3R2,PIP5K1A,PHC1,TENT4A,HAX1,OR13C8,SPRY1,GRAP2,CA2,AKT3,MX1,FOXP3,CD274,PPP1R12A,PPP2CB,ACTL6A,CETN2,PTP4A3,MIEF1,PADI2,GNAO1,TP53INP1,EIF4E,AHCYL1,NDST1,MCM6,UBE2K,POLD4,IMMP2L,GNRH1,TMEM100,MIR96,JKAMP,TNIK,HM13,OR8H3,SEMA4C,LCP2,SFN,GNG10,IFNK,OR2F1,ATG7,HDAC3,INSYN1,CIB2,NUS1,PRKAG1,HHIP,SRXN1,OPTN,CDC42EP4,PNPLA8,HP,BABAM1,SIPA1L1,SAR1B,OR5A2,WNT10B,TXNIP,CRYZ,SMYD3,PAX6,RIGI,AGER,ZNF304,BATF,RHOB,OR10A6,ERAS,TAPT1,MAPK10,OR5M9,CAB39,RDH11,INO80C,EPHA2,RASSF8,CORO1C,MME,OR2A25,CNTNAP1,CINP,RPS3,MS4A7,TRIM6,NMBR,HRH3,CBX5,MRGPRX2,FBXO31,TRAF2,H2AZ1,ROCK2,OR2J3,CCR3,ADIPOQ,FGF17,MLN,PSMD14,HSPB8,UFM1,RHOH,SLC29A1,INA,RASGEF1C,AIPL1,RPS16,STK38L,LDB1,OR5AN1,CFTR,RAB9B,DDR1,OGG1,NKIRAS2,ADO,SPINDOC,H2AX,FBXW11,SPHK2,GPR176,CIDEB,ZNF622,TNFRSF14,CXCL10,NONO,CDK6,TFPT,FAM13B,FAM3C,MICB,CCL11,HUWE1,PTPN11,SCAMP5,TMEM87A,FGFR1,VPS4A,FHIT,MIR34A,PNOC,IL13,MITF,CLEC7A,IL21,APEX2,MADCAM1,SPPL3,TAF7,BLOC1S2,CCNA2,CSNK1A1,PTGER4,SFRP4,RAB39B,RPL23,JAML,CYP7A1,NSDHL,LIPA,RACGAP1,SP1,GPNMB,JUP,SELENOW,RHOJ,OR1S1,RAP2A,BTG2,TSPO,PDE9A,STK24,ITK,RAB32,OR10G2,IL7,CHRNB2,EDEM3,FZD6,TPRA1,ESR2,PYCR1,FBXO22,GAPDH,PLPPR1,TGFB1I1,RAD21,SLC6A4,TPBG,MTDH,ADTRP,ENHO,TOM1L2,GREM1,AP5S1,VPS4B,CDH13,FOLR2,FMO1,PEX13,HSBP1,RAP2B,PTPN22,PDE8A,NFKBIB,ZBTB38,NAT2,GKAP1,ATP5F1B,PCNA,CHP1,TGFB2,CLPB,FCN2,PAK6,NOTCH2,SRPK2,CRIP1,PLSCR3,KLHL12,POLB,CDK7,TAAR6,ATP1B1,FZD3,CTNNA1,TNR,OR51M1,MTARC2,BAZ1B,GPX4,CCL21,HBP1,MIR20A,TADA3,NFE2,RAP1B,TRAF3IP3,MCHR1,PAGR1,SLC25A24,PRKCB,SHC1,CHGA,MACROH2A1,RIT2,TMEM170B,ATP2B4,NCKAP1,NABP1,EDEM1,CRYGD,MAD2L1,CDK5R1,CYP2F1,WDR45,FGF12,SMAD5,SOCS4,USP15,TGIF2,HSP90AA1,HTR2A,INPP5K,APLN,KLF9,CD83,SLU7,IFNAR1,GPR17,PTGES,PRDX3,ZFAND6,SELENOF,IER3,TXNDC17,CREB1,TUBA1B,PRICKLE2,HNRNPA1,DOK6,FMO2,G3BP1,ZNF207,INSYN2A,HBEGF,EGR2,ARL6IP5,LILRB4,RPS27L,POLR2I,S100A11,WWP1,IFT57,MIR421,ARHGAP19,IFIH1,ZMPSTE24,GFI1,MEF2C,CAV3,MSTN,FKBP1B,ERLIN1,HSP90AB1,CD28,DCTPP1,GPBAR1,HTR1A,USP8,RC3H2,ACHE,ATP6V1A,STAP1,AKR1B1,ATF3,FCGR2B,RALB,KLF10,OR5V1,TMIGD3,SELENOK,WNT2,HNRNPD,CCN3,RHBDD3,KLRC2,CRHBP,TAF9,COL1A2,KMT5B,PLSCR4,EIF4A3,SMAD3,CSRNP1,DUSP22,CD63,PLP2,SLC7A11,PDYN,TRIB1,ADGRE2,PACRG,MT2A,CCL19,OR52W1,TRAF6,TICAM2,HP1BP3,NAE1,GSTM4,MRAS,PLP1,CCL4L1,MT1M,B3GNT2,NFKB1,WBP1L,KCNJ8,CYP2C9,RPAP2,SOSTDC1,FBXW4,TAFA1,KLRF1,FOS,CHI3L1,TRIM21,ATF4,HNRNPK,OR2A2,PLCB2,TFPI,PSEN2,FIBIN,ZMAT3,ADRA1A,SRC,PPID,ANGPT1,EXT1,PTGES3,SRGN,NRDE2,TACR3,LGR4,TOM1,ARMT1,PDCL,HBA1,PRKRA,MEF2A,TAB2,IFNG,RNF121,TMEM117,MACROD1,MEIOB,DTL,NUDT4,GPR37,CTNNBIP1,SHOC2,BLOC1S5,FBXO44,NBN,ACTR2,PGK1,FLRT2,IFI16,TFIP11,NTRK2,GSTK1,PQBP1,IRF1,RND3,MAN1A2,MKLN1,BNIP3L,SLC41A1,MOG,BMPR2,ADGRG1,GNG13,TAS2R39,SIGMAR1,NDC80,MECP2,SMAD9,TICAM1,SNX17,AKR1C1,DDI1,MT1E,UBXN6,DRD3,AMELX,GRB10,TANK,SELENOS,GABARAP,AKAP17A,TBC1D4,MIOS,STARD13,LMNA,OR4B1,CDC7,FAM53B,UBE2V2,RNASEH2C,CCL24,IFT25,GPX1,NPR2,SLC1A2,BACH1,CTSK,PIK3R3,NPC1L1,BOK,OR4D6,RNF103,EP300,VDAC2,AP1M1,RFC3,DIRAS2,TRIM24,MSN,CRKL,OR10P1,GNG11,PLAA,MLLT11,GPR160,OR4D5,ADRB3,AATF,NRBF2,G0S2,BAD,GRID1,DERL1,DEDD,AKR1A1,RAMP3,ADCY2,OR1F1,GSK3A,MIR545,NCALD,NPW,TIRAP,BCL2L1,CDKL2,P2RY10,STXBP1,LIMS2,FLOT1,OR10G3,SLC1A3,GPR37L1,MT1X,WSB1,PRELP,IMPA2,SULT1B1,GPX2,HSPD1,TAS2R13,ROPN1B,CBX3,LRRC69,JUN,MORC2,CHCHD6,PPP1R17,BGLAP,MIR107,RTKN,CAMLG,MIR185,UBE2E2,UBE3A,IL12B,RNF14,CXCL9,MYO6,FOXP1,GPR26,STOML2,PEA15,CD9,INHA,ECRG4,AQP4,LILRA2,MSX2,GPX5,MYBL2,OLFM3,RGCC,ABCC2,RGS10,RWDD1,ILDR1,RERG,RMI2,OR51S1,OR8I2,MIR210,BCL2A1,AQP2,APTX,CFC1,VAV2,RRAGB,ELK1,SIN3A,OR6X1 |
| 3.624e-06 | -12.53 | GEMIN2 (gem nuclear organelle associated protein 2) | protein interactions | 8487 | 122 | 58 | 19454 | 5460 |
PSMB1,ACTA2,SRSF1,EGLN3,SNRPD3,DDRGK1,XPO1,SNRNP70,CRTAP,ZCCHC9,DHX9,PAX6,SMN1,SNRPG,SRSF4,KRAS,SPG21,RAF1,COMTD1,CERK,SNRPE,GEMIN7,HDAC11,SIGLECL1,PHF21A,SNRPD2,SNRPD1,SRP54,POLR3B,CHRM4,CCNF,ESR2,TAX1BP1,KPNA6,SNRPB,FBXO7,GPR17,UBE2H,NLRP3,NCKIPSD,BAX,NRP1,GEMIN8,MYO6,LSM6,SNRPA,SNAPC1,BAP1,RPP14,STAU1,KDM1A,SRSF2,FAXC,HCST,SNRPN,GTF2H4,LSM2,P3H1 |
| 3.632e-06 | -12.53 | NSRP1 (nuclear speckle splicing regulatory protein 1) | protein interactions | 84081 | 194 | 84 | 19454 | 5460 |
HNRNPD,ANKRD50,UQCR11,DDX23,HNRNPA1,PPIL4,GAPDH,NDC80,CDK9,FAM98A,HNRNPL,PAIP1,TOP1,MIF,WDR82,SYNCRIP,ILF2,TMEM14B,TAF2,CBX3,DDX42,DISC1,ACTN4,RBM12,RPSA,FBXO25,MEPCE,H3C1,CTNNBL1,CNR1,RPL23A,FAM76B,MRPS11,EMC2,DHX9,RUSF1,SCYL2,SNIP1,PABPC1,HNRNPA2B1,RCL1,UBE2H,ARHGAP19,MECP2,CHORDC1,ANAPC15,RIOK2,ARHGAP21,RBM15B,NONO,CPSF2,CNRIP1,MYC,CIAO1,HNRNPAB,PPP1R10,SNRPB2,APEX1,SRPK2,ACTB,IFI6,SF3B4,RPS9,PSPC1,RPS3,CPSF1,TACO1,CTTN,EZH1,NUFIP2,MFAP1,RPLP0,TOX4,RPA2,ATG16L1,SF3A1,EHHADH,G3BP2,PSENEN,FBXW7,ARHGEF39,HSPA8,SF3B1,SNRPA |
| 3.640e-06 | -12.52 | NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5) | protein interactions | 4725 | 141 | 65 | 19454 | 5460 |
TMEM70,NDUFB8,RAB5C,ACTL6B,NDUFV2,UQCRH,MYL12A,NDUFS8,NDUFB4,PHB1,AIFM1,NDUFA1,CORO1C,PDHA1,NDUFS3,NDUFS6,NDUFA12,EIF1AX,MTCH2,NDUFA2,METTL15,AURKAIP1,DNAJC30,VDAC1,HUWE1,SFXN1,NDUFA4,NDUFB5,BCL7B,HSPD1,CHCHD4,ATP1B3,RIT1,MYC,NDUFB7,NDUFB6,NDUFB10,TOMM40,ACTB,ATP5F1B,NDUFAF4,PARL,UQCRQ,CCDC90B,UQCRC2,LORICRIN,VDAC2,HSP90B1,ARMCX3,COX6C,CYC1,NDUFA5,TIMMDC1,LAP3,TOMM22,NDUFAF3,UQCRC1,PHB2,SLC25A51,PDHB,NDUFS2,HSCB,HADHA,NDUFC2,TMEM126B |
| 3.655e-06 | -12.52 | ATP5MF (ATP synthase membrane subunit f) | protein interactions | 9551 | 114 | 55 | 19454 | 5460 |
MEPCE,DUSP19,ATP5F1D,VDAC1,NDUFA4,ATP5PF,CRELD1,SLC25A20,CHMP4C,FBP1,E2F4,CNTROB,EGLN3,HYPK,MRPL50,RPLP1,COQ8A,PHB1,OCIAD2,TIAM1,ATP5MG,HSPA5,UFL1,KDM1A,FBXW7,RPA3,MME,PML,PRPF4,CAV2,MRPS34,RPA2,CDC42,CFTR,CDK7,ATG16L1,SH3BGRL,UQCRQ,ESR2,VIRMA,MGST3,ATP5F1B,ARMC6,MRPS28,TSSK1B,VDAC2,LMBR1L,BAD,NECTIN2,RIT1,UBE2H,STK24,ATP5F1A,SLC25A1,MYC |
| 3.690e-06 | -12.51 | TRAF5 (TNF receptor associated factor 5) | protein interactions | 7188 | 93 | 47 | 19454 | 5460 |
TRIM8,GAS8,ZMYND11,MAP3K14,TRAF6,TNFRSF14,SRSF1,CIB3,MDM2,SERPINB9,TBK1,THAP1,TRAF2,GARRE1,LTBR,HSD17B10,PICK1,TRIM37,PSMA1,AHCYL1,TICAM1,SEC13,CIAO1,CUL3,CSK,GORASP2,TRAF3IP2,THAP7,NTAQ1,ZFAND6,BEX3,YPEL5,EIF2AK2,ZNF655,TNFRSF9,TRIM27,NMI,SMURF1,HOMER1,SUMO1,TANK,LMO4,COMMD3,SDCBP,CD40,MAVS,CCDC184 |
| 3.696e-06 | -12.51 | CDC27 (cell division cycle 27) | protein interactions | 996 | 240 | 100 | 19454 | 5460 |
CDC23,SKIC8,CTNNB1,CENPW,XPO1,CDC26,PPP2R5A,HMGA1,EGLN3,RBPJ,ZNF526,EZH2,SKA3,ANAPC13,CKS1B,GTF3C3,KRAS,PCNA,TRIM21,MRFAP1L1,NUDT5,RIT1,H1-1,RHOB,BRCA1,CKB,ELMO2,MYC,CREBBP,MAD2L2,ESR2,MAD2L1,PPP5C,LAMTOR3,MCPH1,ANAPC2,FOXP3,UBE2S,ADNP,CDKN1A,SKP1,STAU1,EP300,HSPA8,PYM1,BRD3,LAMTOR2,PGAM1,CDC5L,MXI1,EIF2B2,FZR1,RB1,CDCA3,COMT,RCHY1,SMAD3,H2AZ1,GRAP2,MAD2L1BP,MAP1LC3B,MDC1,RPS13,ANAPC11,H3C1,PSMA5,PTTG1,SMAD2,ANAPC4,GMNN,AR,ANAPC15,CCNB1,PYCR2,CDC16,EMILIN1,DYRK1A,CDC20,ELMO1,BUB3,PTEN,ZNF330,ENO1,CCNF,DCLRE1C,HECTD1,TRIM36,EPHX1,GSTP1,RPA2,CCNA2,NEK2,CCND1,RPS14,NUCKS1,SQSTM1,ANAPC16,RPA3,PPM1G,SNAPC1 |
| 3.696e-06 | -12.51 | ABCD3 (ATP binding cassette subfamily D member 3) | protein interactions | 5825 | 240 | 100 | 19454 | 5460 |
SEC63,DYRK1A,MGST3,CCNF,SPOP,AR,DEPDC1B,RAB2A,TOMM20,MRPL41,FBXW7,KDM1A,RNF113A,MAVS,RAB9A,RETREG2,RPA3,DVL2,MEST,STOM,METTL14,RPA2,CDC42,MPV17,TIMMDC1,ZBTB2,LMAN1,CDK9,PTP4A3,ARF6,RAC2,HSD17B11,ARL10,PTPN1,CD274,HDAC6,SLC25A46,MOV10,FKBP8,MDC1,RAB3B,DHX9,SFXN1,TFCP2,AURKAIP1,MTCH2,ESR2,SEC61B,PHF21A,RMDN3,PELO,BAD,LMBR1L,FIS1,SP1,PSMD14,MLF2,TOMM40,CUL3,SCN3B,RAB11A,MYC,PXMP2,STAU1,UFL1,RAB5A,AKAP1,EP300,EXD2,RND2,PGRMC1,TOMM22,ATP6V1C1,COX14,EGLN3,RHOH,RAB35,HSPB1,HAX1,PEX3,RHOG,DDRGK1,RAB5C,MARCHF5,SYNJ2BP,DYRK1B,UBE2A,TRIM37,PSMA1,KRAS,TMT1A,NDUFA4,CRELD1,RAB4A,PTRH2,PDHA1,EEF2,SOX2,FAF2,RAF1 |
| 3.770e-06 | -12.49 | MED12 (mediator complex subunit 12) | protein interactions | 9968 | 166 | 74 | 19454 | 5460 |
CFTR,MED30,FBXL19,SUPT3H,MED31,CSNK1A1,MED23,MED13L,NR1I3,DDX5,HSPA8,SIRT7,WBP2,G3BP2,FBXW7,SMC4,MED11,KDM1A,AR,RUNX1,ATP5F1A,MED22,CDC16,MYC,CASC3,BRCA1,TADA3,ATG3,STN1,MED10,SEC61B,PTEN,RAN,CCNF,VIRMA,ESR2,POLR2B,FBXO22,MED17,SNRNP40,ATP5F1B,MATR3,SOX9,MED9,CCT5,TOP3B,RAF1,VDR,KLHL12,POLR2C,POLR2G,CDK8,BAG2,TRIP4,POLDIP3,MDC1,RIGI,RPS27A,RUVBL1,THRAP3,ATG7,XPO1,PRPF19,HNRNPD,MED4,MED29,ECD,MED27,MED21,COX20,RPL12,CDK9,POLR2I,NOP58 |
| 3.801e-06 | -12.48 | G-protein beta:gamma signalling | REACTOME pathways | R-HSA-397795 | 51 | 32 | 10285 | 3229 |
IL3,GNB1,GNG7,GNB4,GNG2,GNG12,IL2RA,SHC1,AKT3,GNG3,PIK3CG,AKT1,PIK3CA,PLCB2,GNG13,IL2,GNG10,AKT2,PLCB1,GNG11,IL5,GNG5,JAK1,PIK3R3,IL2RB,GNGT2,GNB3,PIK3R1,CSF2,PIK3R2,IL2RG,JAK2 |
| 3.810e-06 | -12.48 | negative regulation of developmental process | biological process | GO:0051093 | 1000 | 359 | 18204 | 5365 |
MIR214,MIR17,LDB1,ARF6,FOXC2,CCR2,F2,BCL7C,CXCL10,TENT5C,CDKN1A,MIR424,RB1,CITED1,MIR495,BCL7B,HMGB1,HMG20A,PLAC8,BCL6,EPHA2,LBX1,CDK5,RGS2,MIR98,EMILIN1,GABPA,TRIM46,MIR361,DUSP10,FGF3,TWSG1,ACTB,ADIPOQ,TNF,RBBP7,MIR505,LBH,MIR1298,BRMS1L,ROCK2,MIR640,MUL1,RBPJ,NKX6-2,MSX1,MIR145,TRIM6,ING1,TSPO,BTG2,MIR193A,CDKN1B,MIR106A,PI16,SUFU,PPARG,MIR503,MIR212,SLC6A4,TGFB1I1,YTHDF2,B2M,LHX2,ADCK1,GTF2I,EZH2,ITGAV,VASH1,PRDX2,KLF4,TOMM70,CCL11,HUWE1,MIR590,PTPN11,CDK6,TLR4,CER1,DDIT3,BRINP1,ACTL6B,STK4,TP53,MAEL,TNFAIP6,SYNJ2BP,MIR1-1,SOD2,MIR34A,IL13,PAEP,RGN,GHRL,MIR20A,TNR,CTNNA1,SOX9,NDFIP1,SNAI2,DICER1,CBLN1,IFRD1,ATP2B4,SMAD1,MIR29C,TOB2,SAP30L,CCR1,HDAC5,HGS,TMEM176A,TWIST2,SOX2,CEACAM5,DKK1,RFLNA,MIR25,TMEM182,SPP1,C1QC,SEMA5A,KLK3,HAND2,PROX1,ADRB2,GREM1,KRAS,IL1A,TGFB2,LRP3,MIR144,FGF10,ADAMTS1,SPRED2,MIR9-1,MIR208A,RUNX1,LDLRAD4,SOCS5,TCTA,IL4,MIR149,FXN,PTN,MIR146A,PSEN1,LILRB4,TRIM11,IFNB1,CAV1,RC3H2,VGLL4,CBFB,ING2,MSTN,CAV3,FRZB,YWHAH,CCL3,HNF1B,LILRB1,HEY2,STK3,CST3,EFNA3,RORB,MIR106B,EPHA4,TLR3,DLX1,MYC,FERMT2,FLCN,MIR302B,SFRP1,AGO1,MIR142,SOCS2,G6PD,TLR2,GADD45A,SLC12A2,MIR222,PTHLH,RNF10,TRIB1,CTLA4,NPPC,SOSTDC1,PML,MIR16-1,FGF13,MIR205,SAV1,MINAR1,FBXW7,NKX3-1,NOG,FCGR2B,EAF2,HDAC6,STK11,ADIPOR1,MIR24-1,MIR101-1,CERS2,SMAD3,WEE2,CCN3,PDCD1,TRIM62,TFRC,GPR171,PIK3R1,NR2E1,MIR100,IRF1,BRMS1,MIR30E,PGK1,TLCD3B,NIBAN2,SHOC2,METTL14,NFE2L2,MIR137,SOX3,FBXO7,MIR181C,BMPR1A,FGF23,MECP2,BMPR2,VEGFA,NF2,MIR29A,UBASH3B,MGARP,IL18,SRGN,CCDC85B,MIR34C,TMEM176B,FGL2,KRIT1,MIR140,THY1,MIR939,FASLG,LEP,MIR34B,MIR873,IL17F,NLGN1,IFNG,HOXB8,PDCD4,ROCK1,NEO1,MIR143,MIR15A,MIR377,ADRB3,XBP1,MIR320A,KIT,ANP32B,CTDSP1,CCND1,SS18,CDK12,MIR130A,MIR221,IL2,SOD1,CARTPT,MIR492,BCL2L1,PTEN,MIR573,NR1H2,MIR125A,STAT1,NRP1,TMEM215,GSK3A,MIR448,RGMA,MIR182,EID2B,WNT7A,PPP3CA,IL1B,PRMT5,SDHAF2,DRD3,SMAD4,NFKBIA,SAP30,IGF1,SPRED1,BRD9,MIR675,TCF23,WDR77,CALR,SKIC8,RBBP4,CTNNB1,NPR2,CTSK,MT3,RTN4,HDAC3,ZBTB16,ELAPOR2,RGCC,UBE2B,MIR375,MSX2,SYT4,MIR21,IFNA2,MIR30B,CDC73,INHA,MAD2L2,PAX6,SIN3A,MIR204,WNT10B,ACTL6A,PRL,LDLR,FOXP3,MIR885,SPRY1,MIR10A,MIR130B,ADRB1,NEUROD2,PPARA,GPR137,VEGFC,GPR37L1,FOXP1,NKX3-2,MIR185,UBE3A,TP53INP1,MIR379,EIF4E,IL6,ID4,MIR107,MMP9,BGLAP,ASPM |
| 3.822e-06 | -12.47 | Translation initiation complex formation | REACTOME pathways | R-HSA-72649 | 62 | 37 | 10285 | 3229 |
EIF4H,RPS27A,RPS9,RPS13,EIF2S1,RPS29,RPS11,RPS23,RPS2,RPS12,RPS4X,RPS17,RPS10,RPS28,EIF1AX,RPS27L,RPS26,RPS7,RPS5,RPS15,EIF4E,RPS14,EIF3K,PABPC1,EIF3G,RPS3,EIF2S2,EIF3E,EIF4B,FAU,EIF4A2,RPS24,EIF3D,RPS16,EIF3J,RPS20,RPSA |
| 3.868e-06 | -12.46 | regulation of phosphorus metabolic process | biological process | GO:0051174 | 1155 | 409 | 18204 | 5365 |
CACUL1,ROCK1,PDCD4,MIR15A,CAMP,DYNLL1,PIK3CA,IFNG,NTF4,TCIM,TAB2,PHB2,HEXIM1,SQSTM1,LEP,PIK3CG,THY1,MTMR2,RB1CC1,IL18,CSH1,PTGES3,ANGPT1,SRC,VEGFA,SEMA7A,IL23A,UBASH3B,CEP85,NF2,IL15,MIR137,FGF23,CAPN2,NTRK2,TLR8,MIR218-1,NTRK3,CAMK1,NBN,CCNB1,OSM,RAP1A,LACRT,TFRC,YES1,DUSP1,SERTAD1,WEE2,DUSP22,MIR24-1,HDAC6,PRR5L,NKX3-1,FBXW7,STK38,STAP1,STK11,SYK,FGF16,CD40,RALB,DRD1,PIH1D1,TESK1,CHI3L1,DUSP6,HCLS1,NHERF1,MAP2K6,JMJD8,ARL2BP,DIRAS1,CCL19,XRCC5,TBK1,TRIB1,CCNH,GSKIP,TRAF6,GADD45A,CCNF,RARRES2,CAMK2N2,TOM1L1,MOB3B,IL6,BAX,ERP29,GNAQ,IFNA10,MMP9,CD86,YWHAG,IL12B,LDB2,UBE2K,FGR,EEF1A1,CLIP3,PRNP,HAX1,SPRY1,VEGFC,FLOT1,PPARA,PPP1R17,PPP1R12A,ROPN1B,ERRFI1,LDLR,ENO1,CD36,CD80,UCN,PRKAG1,ZNF592,PAX6,SMYD3,MAD2L2,DSTYK,CLEC6A,LCP2,CDKN3,SFN,EHD4,DNAJC3,INHA,TNIK,IFNA2,MIR30B,MIR21,EMP2,HDAC3,MOB3C,TLR9,IFNK,CREBL2,RGCC,PPP2R5A,SMG8,GSTP1,HYAL2,TXN,BAK1,SLC1A1,GH1,CCND3,CCNI,MT3,SPRED1,PDCD10,EP300,IGF1,MIR675,PIK3R3,TLR6,IFNA13,SLCO3A1,GRB10,IL1B,NOP53,TNFSF15,AKT1,GSK3A,PPP1R8,PRKCE,LACC1,CDK5RAP3,DVL2,BAD,DEFB114,TSG101,PTEN,JAK2,GNB3,LRP6,NRP1,PKIB,FGF1,IL2,TGFBR2,ATP5IF1,MIR221,PAK2,TRIM63,CDK12,CCND1,CTDSP1,CRKL,AR,CARTPT,SLC8A1,DIRAS2,SOD1,LMO4,MET,ODAM,PID1,KIT,FAS,IL21,ITGA6,KCTD20,IL13,MIR34A,LEPR,DIPK2A,TAF7,CCNY,SDCBP,FKBP8,SPPL3,TP53,STK4,PTPN11,ZBED3,TRIM27,DLG4,TLR4,APLNR,MIR26B,PTPRQ,P2RY1,FGFR1,RAP2C,ADORA1,GHR,PTPN1,FGF22,EZH2,IL3,CHRNA7,IL7,EPO,LGALS3,CNOT7,APOC2,IL34,IKBKB,MIR212,PPARG,PAQR3,CCNA2,IMPACT,CDKN1B,TSPO,RAP2A,PGR,FAXDC2,SESN2,GPNMB,MIR711,TRAF2,CX3CR1,CDKN2C,AVPR1B,PPP1R1B,RPS3,TRIM6,PHB1,FGF17,TNF,ADIPOQ,DDRGK1,MAP3K11,CAMK2N1,ACTB,FGF3,ROCK2,RAF1,CX3CL1,FBP1,CAB39,BCCIP,DUSP10,PYCARD,HRAS,PKIA,AGER,DNAJC10,FGF7,CORO1C,RGS2,HEXIM2,EPHA2,TAFAZZIN,ILK,STRADB,ADNP,RB1,TNFRSF14,PSMD10,ZNF622,CDKN1A,HSP90B1,SPHK2,TMSB4X,F2,CLDN3,DDR1,YWHAB,LDB1,ACVR1,IGF1R,SFRP1,FLCN,IER3,RTRAF,FERMT2,DUSP19,PRDX3,NUPR1,HSPB1,PPIA,DNAJC30,CCL5,MIR106B,DNAJC19,TLR3,EPHA4,HSP90AA1,MAP3K12,IL6ST,SOCS4,CHRM5,CSF2,PARD6A,CTDSP2,CDK5R1,PSRC1,MIF,TPD52L1,IL12A,BCL10,MIR132,HTR2A,INPP5K,HSP90AB1,AGAP2,FKBP1B,SWAP70,CDKN2D,CAV3,EFNA5,MEF2C,CAV1,IFNB1,SOCS3,TAB1,MAVS,SMG5,IGFBP3,LILRB4,PPP1R2,PSEN1,MIR146A,HBEGF,ARPP19,CD4,SOCS5,CNKSR3,PKIG,IL4,NPTN,FGF10,NCK1,TF,SPRED2,DBNDD1,KRAS,OSBP,CHP1,TGFB2,DUSP3,MAP2K3,CCR7,DDIT4,GREM1,ADRB2,PROX1,C9orf72,TNFSF18,ADTRP,PTPN22,RAP2B,BTBD10,FAM20C,DKK1,HGS,MAP2K1,DIRAS3,IDH1,FCGR1A,MMD,TLR7,FKBP1A,IL5,MACROH2A1,RIT2,FIS1,IGBP1,DLG3,TADA3,MIR20A,RGN,CBL,SOX9,STAT2 |
| 3.927e-06 | -12.45 | UBQLN4 (ubiquilin 4) | protein interactions | 56893 | 249 | 103 | 19454 | 5460 |
PSMC5,FGFBP1,CSNK2B,PSMA6,TXN,CTSB,TRIM32,OAT,VIP,HSPA5,BCL2A1,DESI1,PRL,VPS4B,FA2H,PSMB1,SCG5,SMAD3,CD274,MDM2,SCG2,ORC5,TNFRSF14,H2AC4,SPP1,PPIC,NAE1,PSMA5,SEM1,UBR7,ZMYM4,MLLT6,CD2BP2,EEF1A1,PSMC3,RAD23B,KLHL26,UBE2B,GPX7,TMEM31,PLAAT3,HSPA13,DKK3,ZMYM2,PNMA1,LMBR1L,ESR2,PSMD6,DYNLL1,PSMD4,SRGN,PSMD1,PSMA4,SERPINH1,PSMD14,PSMA3,ATP5IF1,ATP5MK,RNF11,PSMC1,TGFB1I1,CDSN,SRSF2,PTN,PRDX3,GKAP1,CEND1,PSMB3,GJC1,CCL21,ELF5,TYMS,GJA1,MAP1LC3A,PSMB5,TTC9C,C1QTNF1,LAT2,PPIB,VPS26A,WWP2,PSMD3,SMAD9,AGR2,ERP29,PICK1,AHCYL1,PSMD12,FKBP2,UBE2A,DMPK,GJB1,PSMA1,CSTF2T,CYB5R1,CCDC134,TRAF2,CSTPP1,HGS,SMARCB1,PCDH17,KDELR1,RPN1 |
| 3.930e-06 | -12.45 | ARPC4 (actin related protein 2/3 complex subunit 4) | protein interactions | 10093 | 144 | 66 | 19454 | 5460 |
SUMO1,CFTR,PPP1CB,RPA2,RPRD1B,FKBP10,RPA3,ARPC2,HSPA8,CLK1,STAU1,HSPA5,GRPEL1,MYC,USP14,BTF3,PRKACB,NIF3L1,RIT1,UBE2H,CDKN2AIP,VMP1,CALU,EFHD2,EIF3K,ENO1,CTTN,CCNF,MOB4,ACTB,SLC25A4,DAPK1,STAT1,ESR2,SH3BGRL,TOM1L1,PNMA5,TOP3B,FBP1,B3GNT2,SOX2,CHMP4C,ACTR2,CAPZA2,DISC1,PDHA1,ARPC3,EZH2,METTL21A,TFRC,NUPR1,SH3GLB1,PDIA6,WASL,KRAS,MOV10,ACTR3B,HDAC6,BCL7C,XPO1,ATG7,AGR2,UBE2N,SOSTDC1,TMPO,CDK9 |
| 3.930e-06 | -12.45 | COPS7A (COP9 signalosome subunit 7A) | protein interactions | 50813 | 144 | 66 | 19454 | 5460 |
RPA2,UBE2M,WDR77,FBXO42,TOR1AIP2,DET1,HSPA5,RPA3,BTBD10,RAB40AL,FBXW4,DDIT3,DCAF4,FBXW11,DCAF16,NCKIPSD,STK11,DTL,COP1,ANAPC4,NLRP3,MAPRE1,SYCE3,CUL3,CUL2,ATP5F1A,FBXO7,FBXO22,DYNLL1,TOM1L1,VIRMA,JUNB,FBXL14,CTTN,PRMT5,CSNK2B,SYT2,EIF2S2,NFE2L2,RHOBTB1,RAF1,TP53,SOX2,NEDD8,PSMD12,APBB3,COPS4,SAR1B,IMMP2L,EIF3E,PQBP1,IKBKB,CRBN,DCAF11,CDC23,USP15,AP5S1,COPS5,CSNK2A1,FAM98A,DCUN1D1,COPS7B,HSP90AB1,NUF2,KCTD20,COPS2 |
| 3.934e-06 | -12.45 | GSN (gelsolin) | protein interactions | 2934 | 183 | 80 | 19454 | 5460 |
DEPDC1B,BTF3,PDE4B,AR,PPP1CC,CASP4,MYC,CSK,AKT3,RAB11A,FHIT,HSP90AA1,NCKIPSD,VMP1,UBE2H,MYO6,RC3H2,ALB,SESTD1,CTTN,EIF3K,DLST,TOM1L1,SH3BGRL,SRC,ESR2,DAPK1,PSMD4,TMOD3,YES1,ACTB,CFTR,TMOD1,DCTN4,RBM18,STX17,HSPA8,BAP1,GRXCR1,PEBP1,DCTN6,STAU1,HNRNPA1,BCL7C,HDAC6,MPG,PTDSS1,MAP1S,FBXO34,TMOD2,SNRNP70,AGR2,PPM1B,SDHB,TNIK,ACTA2,CDK9,MDM2,PPP1R18,THOC1,ACTN4,ISG15,ACTR1A,B3GNT2,TP53,NUPR1,PIK3CA,TFCP2,EZH2,DISC1,CAPZA2,ACTR2,PIK3CG,ACTR1B,SNIP1,FBXO25,RIGI,TRIM37,WASL,VDAC1 |
| 3.936e-06 | -12.45 | Sf3a1 (splicing factor 3a, subunit 1) | protein interactions | 67465 | 35 | 23 | 19454 | 5460 |
RBM17,SNRPB,TTC33,DNAJC8,SKIC8,CRTAP,SF3B6,SNRPD1,SNRPD2,SF3B4,SNRPD3,SNRPA1,SMURF1,SNRPB2,DHX15,SF3A1,DDX42,P3H1,SF3B5,SNRPE,DDX46,SF3B1,SNRPG |
| 3.945e-06 | -12.44 | NBAS (NBAS subunit of NRZ tethering complex) | protein interactions | 51594 | 101 | 50 | 19454 | 5460 |
SSR1,USE1,ST7,SEC62,OTULINL,SEC22B,PGRMC1,BET1,ATG16L1,NAPG,GOSR1,HSCB,DERL1,RAB9A,OR1M1,DVL2,NAPA,FIS1,SCFD1,DCAF4,GPR17,CUL3,VAMP5,EFNA5,ESR2,VIRMA,COPE,SEC61B,STX12,RPN1,STIM1,MAP1LC3B,DNAJC25,FKBP8,STX18,RINT1,TMT1A,HSPB1,AGR2,SLC25A46,STX6,TOMM70,TMPO,VTI1B,DNAJC1,ANKRD46,HSD17B11,OLFM2,GJA1,PTPN1 |
| 3.945e-06 | -12.44 | PRPF38B (pre-mRNA processing factor 38B) | protein interactions | 55119 | 101 | 50 | 19454 | 5460 |
HECTD1,WRAP53,RPA2,SUMO1,RBFOX2,SAP18,FBXW7,EEF1G,PSENEN,NF2,UFL1,RPA3,UBE2H,RIT1,PEA15,ANAPC15,NOP16,TCEAL7,SRPK2,IFI6,SPCS1,TAX1BP1,AP2M1,EZH1,CCNF,TACO1,TMEM14B,CD2BP2,MAP1LC3B,ESS2,H2AJ,RAF1,DPM2,KRAS,RBBP7,ANKRD50,UQCR11,SNRNP70,MPG,DDRGK1,CTNNB1,YWHAG,PTP4A3,LYAR,PRNP,LSM5,SPPL3,HNRNPL,RPL35A,FOLR1 |
| 3.961e-06 | -12.44 | RELA (RELA proto-oncogene, NF-kB subunit) | protein interactions | 5970 | 456 | 172 | 19454 | 5460 |
PRPS1,CXCL10,TRIM21,IRF8,MTA2,SLC1A2,PGR,COMMD6,SNRPD3,MACROD1,IKBKB,DDX1,RPL6,XPO1,CTNNB1,UBE2D3,SAP18,FOS,HERC3,HSPA8,EP300,NUFIP2,GPC4,AKIP1,PSMD4,STAT1,TCAP,SSH3,IRF2,NFKBIA,DLST,KTI12,NFKBIB,PRMT5,FBXW11,ICAM1,PIWIL4,POLR1B,DNAJB6,LMO2,MYC,CREBBP,PAPOLA,BRMS1,KPNA2,RBCK1,SNIP1,DHX9,PIK3CA,NFE2L2,TP53,CDK4,COMMD8,PLG,GTF2B,SMAD4,SNRNP70,BECN1,AKAP8L,TAF9,KPNA1,CCL5,COMMD5,CSNK2A1,HDAC3,KDM1A,RNASE1,TOMM20,HSPA5,IRF3,PML,HEXIM1,STAT6,KLF4,AGO1,CXCL8,CDC20,NMI,RPS3,ZBTB33,UBE2H,SORD,CCNB1,SUB1,MTPN,AHCYL1,TRIP4,ATF3,BAG2,SRSF7,EZH2,RPN1,VDR,NAA15,GFI1,JUN,ACTN4,MAPK10,HYPK,EGLN3,PPP2CB,UBE2D1,SKIC8,KDM2A,PSMD10,RPL23,ATAD1,SKP1,SAT1,COMMD2,DCTN3,TERT,PPARG,MED23,ACTL6A,RNF182,TIMM13,TAF11,FOXP3,FAS,BRCA1,PAXX,SP1,SETD7,CUL2,RIOK2,IRF1,ANAPC11,TRIM63,EGR1,RIGI,FAF1,SPSB1,NKRF,IGF1R,PPP4C,TBK1,FBP1,SOCS3,PPARA,TIMM8A,TSC22D3,MDM2,CDK9,SMAD3,TIMM8B,MAP2K6,EEF1AKMT3,NFKB1,IRF9,TLE1,HDAC6,GTF2I,HMGB1,FBXW7,PIAS1,AATF,TMUB1,MTDH,SQSTM1,CCND1,CCN3,MX1,UBE2L3,CCNF,STUB1,TXNIP,SMAD2,EPHA2,IRAK1BP1,KPNA6,AR |
| 3.965e-06 | -12.44 | MRPS31 (mitochondrial ribosomal protein S31) | protein interactions | 10240 | 299 | 120 | 19454 | 5460 |
MRPS23,SLC25A12,RBM42,CGAS,FZR1,PRR3,TRMT10B,ALYREF,COX4I1,SRP14,SSBP1,AIFM1,MRPS9,NOL12,DNAJC4,SNRNP70,CHCHD1,TMEM70,E4F1,CSNK2A1,H2AC14,GRSF1,RPL17,FASTKD5,MRPS18C,MEPCE,DNAJC30,SRPRB,MRPS33,IGF1R,CLPB,MRPS18B,GFM2,METTL15,APOBEC3D,DUSP1,AURKAIP1,APOO,MRPL11,MRPS21,PYGM,MRPS28,UBE2H,DNAJC19,IGF2BP1,MRPS16,DNAJC8,TUFM,RPL26,CRYZ,RPL4,SLC25A51,FBXW7,GFM1,BAP1,KLF4,MTRES1,ZNF574,HEXIM1,RPL26L1,FGFR1,GRM2,MRPS34,KLF12,RBMS2,RMND1,HNRNPL,GATD3,FUBP3,ARMC8,MRPS26,RHOG,DDRGK1,TRA2A,HNRNPA1,MRPS35,RPL6,MTRF1,IMMP2L,FLOT1,MRPS17,MRPS11,COX8A,SRSF7,HINT2,PPAN,RBM3,HSPD1,RPL18,PDHA1,TULP3,SOX2,PRRC2A,PARL,ESR2,RPL10,RPL35,RPS9,CCDC90B,MTG1,TACO1,FAM177A1,MCAT,NOA1,MRPS25,PSKH1,CFAP20,PMPCA,CUL3,MTG2,MYC,AUH,MRPS7,PHB2,HSCB,EXD2,NGRN,TIMM29,RPL27A,SYK |
| 3.969e-06 | -12.44 | SUPT5H (SPT5 homolog, DSIF elongation factor subunit) | protein interactions | 6829 | 395 | 152 | 19454 | 5460 |
RPA3,PNO1,PHYHIP,SIRT7,PGK1,ELOF1,RNF34,EIF5B,HDAC3,SAP30BP,INTS6L,CCNH,CDK7,PAK5,RPRD1B,TOX4,RPA2,LMNA,CCNF,TUBA1B,EIF4A3,ENO1,ZNF330,GANAB,CSNK2B,ZNF655,INTS12,MAGOHB,NDN,PPP1R10,CAP2,SUB1,PCBD1,ATP1B3,CDC73,STK11,PDCD4,UBE2H,CPNE2,EMC2,PSMA5,SNRNP48,SEM1,THRAP3,HNRNPK,FGF12,RNF20,MSH6,MNAT1,TP53,MAP2K3,H2AX,WBP11,ZMYM4,CBX3,IK,PPP4C,ILF2,POLR2G,HBP1,NUPR1,H2AZ1,MIOS,THOC1,TOP1,POLR2I,NCBP2,CDK9,CDC5L,MOV10,SETD5,EDEM1,PLEKHO1,CSNK2A1,H2AC4,CLP1,SNRPA,LCA5,DDX39B,SLU7,XRCC5,DDX5,EP300,NUP50,JADE1,EMC1,COIL,WDR77,SUPT4H1,NEK7,NCOA5,DOK4,CMTR1,SNRPD1,PRMT5,INTS10,GTF2F2,POLR2F,SEC61B,SNRNP40,AIPL1,MED17,POLR2B,ERH,APEX1,MYC,HNRNPC,CUL3,PAPOLA,RNF40,SAMHD1,CPSF2,SNRPB,FTSJ3,LMNB1,BRCA1,PLEKHJ1,HSP90AA1,RPL31,FHL3,VPS26B,RPS24,HNRNPF,SSRP1,SUPT5H,DHX38,PPP2R1A,SOX2,EZH2,POLR2D,POLR2C,MOB3C,SSBP3,RPL9,CCDC71,PPP2CB,POLR2L,OCIAD2,SWAP70,MRTO4,WDR82,SUMO2,PPIA,WIF1,IFI16,HMGA1,BAZ1B,WWP2,DDX23,SKIC8,CDKN1B,HSPB1 |
| 3.984e-06 | -12.43 | MRPL40 (mitochondrial ribosomal protein L40) | protein interactions | 64976 | 169 | 75 | 19454 | 5460 |
COX8A,EMC2,HINT2,MRPL52,RPL17,IMMP2L,FASTKD5,SRSF4,KRAS,METTL15,AURKAIP1,MRPL47,MRPL11,ATP5PB,MRPL51,TFCP2,GATD3,FAHD1,MRPS9,SSBP1,SDHB,STK3,MRPL24,CDC5L,MALSU1,MRPL50,FZR1,MRPL9,STOML2,GRSF1,MTRF1,HSPB1,ATP6V1D,MRPS26,TMEM70,SNRNP70,CHCHD1,MRPL18,RHOG,HADHA,GFM1,EXD2,NGRN,MRPL41,PHB2,HSCB,RBMS2,MRPL12,MRPL10,MPV17,RPL27A,MTRES1,MRPS18A,MRPL13,TRIM27,KRTAP3-1,DLST,TACO1,MRPL53,RPL10,RPL19,RPL13A,TAX1BP1,RPL35,MRPL23,TUFM,MRPL16,PMPCA,HNRNPC,MYC,AUH,MTG2,ZMPSTE24,SCFD1,ATP1A1 |
| 3.992e-06 | -12.43 | UCHL1 (ubiquitin C-terminal hydrolase L1) | protein interactions | 7345 | 223 | 94 | 19454 | 5460 |
IDH2,CDK1,RPA2,GSTP1,SPR,DDAH1,NDUFAB1,USP8,HSPA5,POLDIP2,BCL6,GRPEL1,BAP1,RPA3,SOD1,SQSTM1,DERL1,PRDX6,PPTC7,GLOD4,KCNB1,UBE2H,ATP1A1,SMAD2,CCNB1,AKT1,TUFM,TRIM54,NDN,UBB,CTTN,ENO1,UBE2I,ALB,CDK4,ANKRD6,TP53,PGM1,TRIM63,NEDD8,SMN1,RPL17,SMAD4,USP15,DPP4,TPM3,COPS5,MDM2,AIP,SMAD3,CD274,AIFM1,HDHD3,CDK6,RB1,KLF3,FKBP10,STXBP1,OXCT1,ADRB2,PYGB,PMAIP1,NMRAL1,HSPA8,YWHAZ,HSP90AA1,CUL3,MYC,ACO2,CLIC4,DLST,NFKBIA,ANAPC2,NGB,EZH2,CPT1B,TUBA1A,SAR1B,RPS27A,RPS4X,AKT2,PLA2G4B,CDK5,MYO1B,HINT2,TRAF6,CDKN1B,LAMP2,IFI16,CTNNB1,MITF,HSP90AB1,GATD3,WDR82 |
| 3.999e-06 | -12.43 | CSDE1 (cold shock domain containing E1) | protein interactions | 7812 | 252 | 104 | 19454 | 5460 |
LMBR1L,SNRPD2,TSN,TAX1BP1,PSMD6,ESR2,PRRC2A,PSMB6,CUL3,CUL2,MYC,BAG3,BTF3,RNF40,BRCA1,LSM14B,XRCC5,MCRIP2,EP300,HSPA8,ARHGEF39,STAU1,YTHDF1,UFL1,G3BP2,PABPC5,CNPY3,RNF7,LARP4B,PSMB7,CNDP2,PHB1,FUBP3,PAIP1,HNRNPL,DHX15,PPIA,WWP2,PSMD3,DDRGK1,ATG7,XPO1,HNRNPA1,PSMD10,ARHGAP5,HNRNPD,HNRNPA2B1,PABPC1,CCT8,BAG2,ZC3H7A,HNRNPF,G3BP1,SSRP1,PSMD12,SUPT5H,TOP3B,RAF1,PPP2R1A,MOB3C,CCNF,RPS20,GANAB,ADRM1,NDN,VIRMA,BICD2,UBE2H,IGF2BP1,PML,SIRT7,RPA3,RNF113A,LSM12,AATF,HSPA5,UGP2,AGO1,METTL14,RPA2,JUP,PTPN1,STT3A,SYNCRIP,CAND1,FZR1,GMPPB,KARS1,MOV10,COPS5,SNRNP70,TSNAX,MAP4,SNIP1,NAE1,DHX9,HNRNPK,TTC4,HUWE1,CAPZA1,RNF20,TP53,KIF1C,YTHDF2 |
| 4.000e-06 | -12.43 | ANAPC4 (anaphase promoting complex subunit 4) | protein interactions | 29945 | 125 | 59 | 19454 | 5460 |
PTTG1,ANAPC4,BAX,BRCA1,RACGAP1,ANAPC15,DEPDC1B,PYCR2,CCNB1,PYCR1,CUL3,CDC16,COPS7A,ESR2,DYRK1A,CDC20,MAD2L1,FBXO22,BUB3,ANAPC2,UBE2I,PTEN,UBE2S,FAM91A1,CDK1,CCNA2,NEK2,TIMM13,FHOD3,H1-5,SKP1,FBXW7,GPHN,ANAPC16,RPA3,POU5F1,SMG8,CDC23,DCAF11,XPO1,CDC26,MXI1,CCT7,NUP35,FZR1,HP1BP3,COPS2,KLHL7,SRP14,MAD2L1BP,SOX2,ANAPC13,TUBA1A,UBL4A,MDC1,RAD21,ANAPC11,KRAS,PSMA5 |
| 4.028e-06 | -12.42 | Asparagine N-linked glycosylation | REACTOME pathways | R-HSA-446203 | 284 | 125 | 10285 | 3229 |
GMPPA,SEC23A,RPN1,LHB,SEC22B,B4GALT1,SLC35A1,KDELR1,GOSR2,PREB,MVD,LMAN1,STT3A,TRAPPC6A,TRAPPC6B,TUSC3,RPS27A,ARFGAP1,DERL1,ST8SIA4,FOLR1,ST3GAL4,PDIA3,PSMC1,ARF4,DYNC1I1,ALG5,ALG11,CD59,SLC35C1,ST3GAL2,TRAPPC10,ST8SIA5,B4GALT4,GNPNAT1,ST3GAL5,CNIH1,MIA2,CHST10,TMED7,SRD5A3,SEC13,UBA52,CMAS,COPE,GANAB,TMEM115,TRAPPC3,ARF1,DOLK,DYNC1I2,FUT8,GRIA1,GMDS,SAR1B,DCTN4,SPTAN1,SCFD1,ARCN1,GFPT1,BET1L,EDEM1,DCTN6,MGAT4A,TFG,SEC22A,NANP,DPAGT1,MPDU1,DYNLL1,EDEM3,ALG2,NEU1,DPM2,MGAT4B,RAD23B,CTSA,TRAPPC1,SEC22C,CALR,FPGT,RNF103,COPZ2,NUS1,TMED9,EDEM2,ARFGAP3,YKT6,SPTBN1,GOSR1,TMED3,MAN1A2,ST6GALNAC3,TRAPPC2L,B4GALT3,BET1,RNF5,DERL2,GFUS,ST3GAL1,UBB,SYVN1,COG1,TRAPPC4,STX5,PMM2,SERPINA1,B4GALT6,RAB1B,OS9,RAB1A,RNF139,UAP1,ST6GAL1,KDELR2,STX17,MGAT1,NAPA,MIR711,DCTN3,GMPPB,NAPG,DAD1,SLC17A5,CTSC |
| 4.031e-06 | -12.42 | negative regulation of leukocyte adhesion to vascular endothelial cell | biological process | GO:1904995 | 13 | 12 | 18204 | 5365 |
KLF4,MIR221,MIR141,MIRLET7G,MIR146A,CCL21,CXCL12,MIR125A,CCL25,MIR222,MIR31,CCL28 |
| 4.032e-06 | -12.42 | negative regulation of smooth muscle cell proliferation | biological process | GO:0048662 | 70 | 39 | 18204 | 5365 |
MIR15A,MIR143,MEF2C,MIR34A,MIR424,SOD2,MIR145,MIR1-1,PDCD4,BMPR2,TNFAIP3,IFNG,IL12B,IL10,CDKN1A,MIR339,MIR1298,MIR185,MIR223,MIR137,PTEN,ADIPOQ,MIR638,MIR96,MIR140,TRIB1,CTNNBIP1,AIF1,PPARG,IGFBP3,MIR503,KLF4,TGFB3,APLN,OGN,IL12A,MIR214,CDKN1B,MIR182 |
| 4.069e-06 | -12.41 | ACTR1A (actin related protein 1A) | protein interactions | 10121 | 255 | 105 | 19454 | 5460 |
ACTA2,CD274,PRNP,FZR1,CDC5L,MOV10,COPS5,HDAC6,USP15,TTC4,KPNA2,DYNC1I1,HUWE1,CAMK2G,PTGES3,MSH6,CAPZA1,MEPCE,CCT5,COMMD8,FBP1,ACTR1A,CAPZA2,ACADSB,RNF181,CCNF,GANAB,NDN,DYRK1A,DEK,VIRMA,SMURF1,SUB1,STK24,BICD2,MAPRE1,UBE2H,BMERB1,DCTN6,BAP1,RPA3,SQSTM1,SMC4,SPTBN1,PSMC4,AKR7A2,SF3A1,CFTR,HSP90B1,RPA2,DCTN4,UBE2M,HEXIM1,DYNC1I2,TCP1,CCT7,CACYBP,PFDN5,AGR2,FKBP4,YWHAB,RB1CC1,MED4,CCT8,ACTR1B,RPAP3,G3BP1,MCM6,CCAR1,RAF1,TOP3B,NUDCD3,SOX2,TUBB4B,MOB3C,POLR2D,MTA2,PRMT5,ACTB,DYNLL1,RBBP4,MATR3,APEX1,CUL3,MYC,VEZT,MCM4,PSMD1,BTF3,LMNB1,CCT2,PFDN6,RIT1,PFDN2,SCFD1,TTC1,DCTN3,RAB5A,HSPA8,TXNL1,UFL1,PACSIN3,EHHADH,PPT1,PIH1D1 |
| 4.082e-06 | -12.41 | ARL13B (ADP ribosylation factor like GTPase 13B) | protein interactions | 200894 | 314 | 125 | 19454 | 5460 |
JAGN1,CDC42EP2,RAB5A,SLC31A1,STX7,NOTCH2,GOSR2,CLDN4,VAMP1,CCDC167,TMUB2,SMCO4,FDFT1,CMTM7,TMEM229B,FAM83B,CYB561D2,RAB11A,WDR20,RHOB,MYO6,LAMTOR1,FAXDC2,PLN,TMEM60,KRAS,PAEP,FLOT1,RAB18,SACM1L,LEPROTL1,PGAP2,TNPO2,RAB4A,CTSA,VAMP2,TUBB4B,TMEM14B,IFT22,HOMER3,RAB35,GJA1,RHOH,TMEM97,TSPO2,SLC38A7,RAB5C,PMP22,PLPP4,LAMP2,ATG9A,RHOG,FXYD6,ANKRD50,C2CD2L,STX1A,PDZK1IP1,ORMDL1,TEX264,RHOU,RAB9A,CLDN8,ENTPD3,TMEM254,NF2,SLC7A1,ATG16L1,CDC42,PLP2,STOM,NECTIN2,GAB1,CCNF,VAMP3,CDIPT,PLP1,UBE2I,MMD,RHOJ,TECR,SH3BP4,FERMT2,VAMP5,GJB2,RAB2A,DNAJC5,HMOX2,CSGALNACT2,PKNOX1,KCNJ2,DLG1,CLEC7A,RUSF1,STX8,GAD2,ERG28,IFT52,RAB3B,GPR37L1,AKAP12,FKBP8,CTNND1,INSIG2,NRM,CTDSP2,TFRC,APEH,VAC14,RAC2,ADD1,CD151,ANKRD46,ARF6,CAV1,AIG1,FUNDC2,STX6,RELL1,ORMDL3,LAMP3,SLC35A1,TMEM11,BTN2A2,TMEM190,ZDHHC15 |
| 4.099e-06 | -12.40 | RANBP2 (RAN binding protein 2) | protein interactions | 5903 | 317 | 126 | 19454 | 5460 |
PTGES3,HNRNPK,KPNA2,NUP107,EMC2,DHX9,PPP1R12A,NUPR1,ILF2,IK,H2AX,DDX39A,EEF1A1,TP53,KBTBD4,COMTD1,CDC5L,MDM2,TES,RCHY1,CTDSPL2,KPNA1,SNRNP70,NXT2,GAPDH,PPM1D,RBM17,KDM1A,B2M,RNF113A,PML,SIRT7,BAP1,RPA3,UBE2M,RPLP0,RSAD2,LMNA,RPA2,CFTR,POLR1D,SUMO1,TPT1,ATG16L1,RPS14,VIRMA,NDN,PTEN,ALB,UBE2I,RBMX2,CTTN,UQCRC2,CCNF,MAPRE1,RRP7A,UBE2H,CDC73,XPOT,BICD2,PRKACB,SUB1,SMARCA5,SUGP1,SLC25A1,RALB,SSRP1,G3BP1,HNRNPF,PCNA,ARGLU1,TOP2B,HSPD1,MOB3C,TUBB4B,EZH2,LGR4,NUP153,RANBP1,NUP35,DHX15,CHMP2A,EGLN3,SNRPA1,SUMO2,KIF3B,EED,TRAF3IP3,BCL2L1,CTNNB1,XPO1,ADRB2,STAU1,EMC1,HSCB,NUP50,SF3B1,HSPA8,PIH1D1,IER2,NUP62,TNPO3,ESR2,UBTD1,TUBB,PDLIM3,MATR3,PHF21A,SMU1,PRMT5,RSRC1,RAN,NFKBIA,LMBR1L,S100A6,RIT1,FBXW11,LMNB1,BAG3,PSMD1,BTF3,AK3,CUL2,HNRNPC,CUL3,MYC |
| 4.112e-06 | -12.40 | ribosome biogenesis | biological process | GO:0042254 | 306 | 127 | 18204 | 5365 |
NLE1,POP5,WDR12,RPS14,RPS17,RNASEL,PELP1,NOP9,RPL23A,UTP6,WDR55,RPL35,NOP58,ZNHIT3,EMG1,RRP7A,RCL1,MRPS7,UTP25,RPL35A,RPS15,TRAF7,PWP2,IMP3,MPV17L2,RPS12,LYAR,LSM6,RPS11,NOA1,RPS23,FCF1,NOB1,RPL7A,RBIS,RPS9,EXOSC1,MPHOSPH10,RPS5,RPL26L1,RPLP0,EXOSC3,SURF6,DROSHA,RAN,KRR1,MPHOSPH6,SUV39H1,NGDN,UTP15,ISG20L2,RPL10,NOP16,RPS24,YBEY,RPL10L,WBP11,RBM34,MTG2,RPP25,RPS27L,RPSA,DKC1,PAK1IP1,PNO1,XPO1,EIF1AX,NGRN,POP7,GTF2H5,RPF1,TRMT112,GLUL,EIF4A3,LTO1,TMA16,MRM2,CINP,MAK16,RSL24D1,NOP53,NOC4L,NPM3,METTL15,RPS4X,EXOSC8,RPS7,NOL7,RPL26,BRIX1,ISG20,ZNHIT6,MALSU1,NHP2,RIOX2,RPF2,MRTO4,ZNF593,BUD23,TSR2,EIF5B,PPAN,FTSJ3,ZNF622,SRFBP1,RPL6,WDR3,PIH1D1,TFB1M,METTL25B,ABCE1,C1D,NSA2,RPL27,AATF,RIOK2,RPL7,TSR3,EXOSC4,RPS13,RPS16,UTP23,IMP4,RPL7L1,RPS28,RRN3,XRCC5 |
| 4.115e-06 | -12.40 | GNL3 (G protein nucleolar 3) | protein interactions | 26354 | 320 | 127 | 19454 | 5460 |
SYK,MTF1,PPARG,EMC9,MAP2K1,PIH1D1,EP300,RAB5A,UFL1,STAU1,MRPL57,G3BP2,MYC,CUL3,MRPL16,DCAF4,FTSJ3,ATG3,SP1,RPS5,RIT1,H1-1,DLST,RSRC1,RPL37A,MRPL13,SEC61B,RBBP4,SNRNP40,RPL10,RPL19,APEX1,RAF1,E2F4,SOX2,ISG15,RPS7,CHMP4C,PDHA1,RPL18,RPL31,ARGLU1,PPAN,RPS24,RBBP7,KRAS,G3BP1,RPS4X,SSRP1,IFI16,RPL6,WWP2,PPP2R5A,MRPL9,MAP3K14,DDRGK1,DDX23,CDKN1B,RPL23,DRG1,PHB1,EED,NOP58,HNRNPL,RPL7,KCTD10,CEP19,RPS14,KLF12,LMNA,RPA2,METTL14,HEXIM1,RPA3,BAP1,SIRT7,NLE1,RNF113A,MRPL17,RPL4,FBXW7,HMGB1,SUB1,FBXO7,USP14,PPP1CC,AR,RC3H2,UBE2H,RRP7A,CCNF,RPS3,PSPC1,ZNF330,EIF2AK2,TNFRSF1B,METAP2,EIF4A3,PRKRA,RBMX2,PTEN,NDN,BCCIP,TP53,AURKAIP1,RPL15,RBM34,DNAJC2,MRPL51,SRP72,SNIP1,H3C1,GRSF1,RBM17,COPS5,MPG,SNRNP70,RCHY1,KRR1,RPS16,CAND1,FZR1,MDM2,DKC1,RBM42,ZBTB2,SURF6 |
| 4.126e-06 | -12.40 | SLC25A20 (solute carrier family 25 member 20) | protein interactions | 788 | 63 | 35 | 19454 | 5460 |
RAMP3,ACTB,MGST3,PRDX2,OCIAD2,CYB5R3,SYNCRIP,VDAC2,ACOX1,CCNF,FIS1,HNRNPD,TOMM40,ATP5MG,SLC25A1,PDE2A,VDAC1,KDM1A,HADHA,GNG5,HSPA8,SFXN1,ATP5MK,SLC25A5,RAB1A,SLC25A3,JPT2,ARL15,TMEM205,CTDSP2,CRAT,CYB5R1,MGARP,DDX39A,PREB |
| 4.126e-06 | -12.40 | UFC1 (ubiquitin-fold modifier conjugating enzyme 1) | protein interactions | 51506 | 63 | 35 | 19454 | 5460 |
NECAP1,RPA2,FKBP1A,CCR1,TPT1,SPR,UBA52,NECAP2,ETFA,KRAS,UFM1,YKT6,UFL1,NEDD8,LYPLA2,SAR1B,AHCYL1,SOD1,ZYX,RPA3,HINT1,COX17,CDK5RAP3,RIT1,UBE2H,LDHB,CRIP1,DDRGK1,CAPG,NTAQ1,SPPL3,TTC9C,TAGLN2,UBA3,TYMS |
| 4.128e-06 | -12.40 | AARS2 (alanyl-tRNA synthetase 2, mitochondrial) | protein interactions | 57505 | 323 | 128 | 19454 | 5460 |
MTRES1,MRPS34,QRSL1,IDH2,MRPL10,CFTR,CNP,GRPEL1,POLDIP2,MRPL20,NME4,MRPL41,FBXW7,MRPL40,TWNK,DLAT,GFM1,RPA3,AMACR,OAT,MRPS16,ATP5F1A,TUFM,NDUFAF2,PYCR2,SUCLG2,VIRMA,MRPS28,PTPMT1,ACAT1,ZNRF1,NDUFS3,DISC1,ACADSB,PPIF,METTL15,IL1R2,FASTKD5,ABHD10,PDE12,HSPE1,HSD17B10,ATP5PF,TRMT5,SCGB1D1,LYPLAL1,GRSF1,KARS1,DBT,MRPL24,PRNP,MRPL50,RAP1B,SSBP1,MRPS9,COQ8A,SDHB,COX4I1,MGME1,ACAA2,IDH3B,MRPL12,TIMM29,EHHADH,NT5C3A,MRPS7,HSCB,NDUFS2,PHB2,ATP5IF1,HSPA8,HADHA,NGRN,EXD2,FBXW11,NOA1,AK3,AUH,MTG2,PMPCA,PYCR1,CUL3,MRM2,GPR17,PSMB6,ESR2,NDUFAF4,ATP5F1B,TRMT11,SEC61B,IRF2,TACO1,LMBR1L,DLST,MTG1,NDUFA12,NUDT19,NDUFS6,PDHA1,HSDL2,ETFB,MRPS17,IMMP2L,USP30,KRAS,ETFA,KGD4,HINT2,EFNB1,COX8A,MRPS11,HSPD1,PREPL,RBM3,THNSL1,MRPS26,RHOG,YWHAH,NDUFV2,CLPX,MTRF1,PFDN5,MRPS35,STOML2,PNPLA8,GATD3,FAHD1,PHB1 |
| 4.129e-06 | -12.40 | CCDC9 (coiled-coil domain containing 9) | protein interactions | 26093 | 83 | 43 | 19454 | 5460 |
NKAPD1,ARGLU1,TMT1A,DDX39B,SNIP1,SRSF8,SRSF7,EP300,ZC3H11A,NUP42,MDC1,SAP18,KIF1C,ZC3H14,PABPC5,ATG16L1,CFTR,RALYL,PPP2R1A,PNMA2,CTBP1,EZH2,AAMP,TMEM184B,EIF4A3,TUBA1B,THOC2,TBCCD1,SPPL3,PAIP1,VTI1B,AKAP17A,HNRNPC,STN1,AGR2,SNRNP70,DCAF4,FYTTD1,NIF3L1,MAGOH,CASC3,ELAVL2,ID1 |
| 4.139e-06 | -12.39 | MRPS27 (mitochondrial ribosomal protein S27) | protein interactions | 23107 | 326 | 129 | 19454 | 5460 |
EXD2,NGRN,NOP53,STAU1,HSCB,UFL1,MRPS7,MRPL12,TIMM29,MTG1,CCDC90B,TACO1,FBXO22,RPL35,ESR2,PRRC2A,RPL10,NOP16,CUL3,PMPCA,MTG2,MYC,AUH,RIOK2,FBXW11,NOA1,MRPS25,PSKH1,MCAT,LSM14A,HSPD1,MRPS11,COX8A,SRSF7,HINT2,KRAS,IMMP2L,MRPS17,RAF1,SOX2,PDHA1,CHMP4C,PHB1,FBXO31,THOC2,GATD3,RMND1,MRPS35,RPL6,MTRF1,DDRGK1,TRA2A,HNRNPA1,RHOG,MRPL18,MRPS26,BAP1,RPA3,GFM1,RPL4,SLC25A51,RPS15,NPM3,CRYZ,KLF12,RBMS2,CFTR,GRM2,MRPS34,RPA2,LUC7L3,MTRES1,KLF4,HAUS2,ZNF574,HEXIM1,CCNF,PTEN,MRPS28,MRPS21,VIRMA,SMURF1,TUFM,RC3H2,MRPS16,UBE2H,DNAJC19,IGF2BP1,CLPB,HAPSTR1,MRPS18B,MRPS33,SNRNP48,H3C1,RPL17,FASTKD5,MEPCE,MRPS18C,MRPL11,TP53,STRBP,METTL15,APOBEC3D,AURKAIP1,GFM2,ALYREF,COX4I1,RCHY1,SRP14,COQ8A,SSBP1,MRPS9,PRR3,TRMT10B,CGAS,FZR1,DNAJC1,CAND1,MRPS23,CDK9,MOV10,GRSF1,COPS5,CHCHD1,SNRNP70,TMEM70,TSNAX,DNAJC4,NOL12 |
| 4.149e-06 | -12.39 | AATF (apoptosis antagonizing transcription factor) | protein interactions | 26574 | 329 | 130 | 19454 | 5460 |
SNIP1,DHX9,ZC3H11A,RPL3,IMP4,THRAP3,NOC4L,EIF3E,RPL17,CCT5,TP53,RPSA,LLPH,KRR1,RPL32,SRP14,SMAD3,RB1,RPS27L,THOC1,CAND1,RPS16,RPL35A,SURF6,MRPS23,NCBP2,MDM2,NOS1AP,MPHOSPH10,H2AC4,CHCHD1,EXOC2,RPS2,SIRT7,RBM22,RPL4,NPM3,DGCR8,BRIX1,AATF,LDOC1,EIF4E,FGF13,ZNF326,MRPS34,RPLP0,ZNF330,RPS3,RPS20,MSN,PRKRA,FGFBP1,RPL13A,MAGOHB,DAPK3,RPL22,SRPK2,RPL7A,SLC25A1,RPF2,AR,RPL26,FBXO7,MRPS16,IGF2BP1,HNRNPA2B1,SLC25A5,RPL31,RPS24,MYO1B,KRAS,DHX16,UTP25,SRSF4,RPS27A,CCAR1,E2F4,RAF1,KIF2A,H1-3,RPS23,FUBP3,SRSF1,RPL8,THOC2,TSG101,CCAR2,RPS10,HNRNPL,RPL6,DDX50,PRPF19,IFI16,NGDN,UTP6,HNRNPA1,XPO1,DDX23,MPHOSPH6,DDX39B,EMG1,HSPA8,PHB2,STAU1,FXR2,ZC3H14,PPP1CB,PALS2,EIF4B,RPS9,SNRNP40,RPL35,MATR3,RPL10,PRRC2A,RPL19,ESR2,HNRNPC,RAB11A,MYC,ZNF668,H1-10,ATG3,CHTOP,FBXW11,MRPS25,BRCA1,H1-1,RCL1,SP1 |
| 4.169e-06 | -12.39 | outer membrane | cellular component | GO:0019867 | 250 | 106 | 19108 | 5553 |
FUNDC1,DCAKD,ATP5MC3,BAK1,TUFM,BNIP3L,MUL1,MTARC2,MAVS,CNR1,SAMM50,FATE1,PHB2,TRAF3IP3,DMPK,RAC2,TAFAZZIN,STARD7,MARCHF5,CNP,SH3GLB1,RMDN3,USP30,AGK,ARMCX2,SIGMAR1,TOMM40,SYNJ2BP,CYB5B,GK2,SNN,VDAC1,AKAP1,ACSL4,MGARP,THG1L,UFL1,CYP27B1,PMAIP1,ENO1,BOK,PGRMC1,GPAM,TOMM22,FIS1,MCL1,CHCHD3,CYB5R3,EPHA4,MFN1,VDAC2,BCL2A1,ATAD1,TOMM40L,RETSAT,CPT1B,MGST3,SLC25A46,HAX1,DELE1,ARMCX3,CYB5A,TOMM7,SYNE4,FUNDC2,ANKH,VAMP1,CISD1,PPP1CC,BAD,PSEN1,MTCH2,MIEF1,MTX2,APOO,SLC11A2,CHCHD6,TOMM20,KRAS,BCL2L1,ARMC1,TOMM6,TSPO,RAF1,HINT2,IFI27,QTRT2,EXD2,CPTP,UBA52,MT3,RAB32,UBB,PTRH2,AGPAT5,SARM1,BECN1,ARMCX1,PGR,PDE2A,RSAD2,TOMM70,COX14,SFXN2,BAX,RPS27A |
| 4.204e-06 | -12.38 | PPFIA1 (PTPRF interacting protein alpha 1) | protein interactions | 8500 | 206 | 88 | 19454 | 5460 |
RAF1,CARTPT,PPP2R1A,TULP3,VPS33A,PPFIA2,RND3,RPAP3,PICK1,PDIA6,UBE3A,KRAS,FLOT1,PIK3R1,PPP2R5A,YWHAH,YWHAG,PPFIBP1,GAS8,RHOG,DROSHA,YWHAB,RAB35,PPP2CB,GJA1,PPFIA3,RPS10,SPTAN1,OSBP,RHOH,DYNC1I2,DIRAS3,EGLN3,RND2,CDKN1A,STAU1,POLA2,STX7,SFN,CUL2,RAB11A,PSMD1,LAMTOR1,RHOB,BRCA1,YWHAZ,EXOC8,RIT1,PHF21A,MTM1,FBXO22,ACTB,ESR2,APEX1,PPP4C,NTRK2,TOLLIP,STX11,TUBG1,HRAS,RAC2,ARF6,FZR1,STX6,CAV1,CDC5L,PSMC4,ATG16L1,FAM161A,CDC42,CCNH,RPA2,FGFR1,RPA3,RHOU,RAB9A,NF2,KDM1A,RAB2A,DNAJC5,CEP70,ST13,PIP4K2C,GSK3A,NDN,RHOJ,VIRMA,DYRK1A |
| 4.289e-06 | -12.36 | THOC1 (THO complex subunit 1) | protein interactions | 9984 | 189 | 82 | 19454 | 5460 |
RNF8,NUPR1,IK,PDHA1,CAAP1,NFKBIL1,UBR7,ESS2,DDX39A,E2F4,KIF1C,SUPT5H,TOP3B,RAF1,PAX6,SSRP1,POLDIP3,MRPS17,B4GALT7,ATG4A,THRAP3,KRAS,RTCB,DHX9,ZC3H11A,MED4,AGR2,TPM3,FRA10AC1,TNFAIP6,TOP1,THOC1,OCRL,RB1,SRSF1,ALYREF,THOC2,TRMT112,TFIP11,MFAP1,RPA2,MRPL12,ZC3H14,WDR77,SF3A1,ACTL6A,ATG16L1,SAP30BP,AATF,ZC3H15,STAU1,RBM22,TRA2B,SF3B1,DDX39B,CCDC9B,RPA3,THOC3,SNRPA,RIT1,THOC6,BRCA1,RBM27,CHTOP,FYTTD1,SNRPB,RBM15B,GPRASP3,EXOC5,RNF40,USP13,MYC,BCCIP,ESR2,MED17,TRIM54,RTRAF,TRIM27,DLST,GCFC2,CMTR1,EIF4A3 |
| 4.293e-06 | -12.36 | PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1) | protein interactions | 54984 | 96 | 48 | 19454 | 5460 |
SNRNP40,GABPA,TXN,APEX1,ZNF330,ALB,FGFBP1,LMNB1,PLEKHJ1,H1-1,MYC,NTAQ1,MPZ,FBXW7,PAFAH1B2,DGCR8,COIL,RPS28,TERT,EP300,LMNA,RBMS2,ALCAM,RPS10,FAM98A,RPS16,DHX15,CACYBP,SRSF1,GYS1,RPL8,SNRNP70,DDX23,HNRNPD,IFI16,H3C1,PABPC1,EIF1AD,RPL31,RPS24,RPL23A,RPL3,CBX3,TFRC,H2AJ,RAF1,UBL5,TNPO2 |
| 4.293e-06 | -12.36 | precatalytic spliceosome | cellular component | GO:0071011 | 52 | 31 | 19108 | 5553 |
SMU1,RBMX2,SNRPA1,SNIP1,LSM2,RNF113A,SF3B6,SNRPD2,MFAP1,LSM6,DHX16,PRPF31,SNRPB2,SNRPE,SNRPG,LSM4,PRPF4,IK,SNRPD1,LSM3,SNRPB,SNRPD3,MAGOHB,LSM5,TXNL4A,SF3B4,LSM8,SF3B5,SF3A1,ZMAT2,SF3B1 |
| 4.303e-06 | -12.36 | BCR (BCR activator of RhoGEF and GTPase) | protein interactions | 613 | 232 | 97 | 19454 | 5460 |
SIN3A,IL3,GYS1,TSG101,WDR82,HNRNPL,EGLN3,PIK3R1,YWHAH,ATG7,XPO1,YWHAG,CBL,YWHAB,HSPD1,PIK3CG,KIT,MCM6,GTF3C3,TRMT1L,TOP3B,GABARAPL1,TULP3,VPS33A,PNMA2,CRKL,SH2D5,SLA2,AP2M1,PHF21A,DYNLL1,RBBP4,ESR2,JAK2,MYC,SFN,GRB10,MCM4,RHOB,ATG3,YWHAZ,PSMD14,HSP90AA1,HSPA8,HSCB,NOP53,ARHGEF39,STAU1,G3BP2,IGSF21,NRDE2,USP39,CSNK1A1,PTPN1,RB1,NKAP,SURF6,ERCC3,CSNK2A1,API5,SHC1,USP15,DDR1,MAP1B,DLG1,RIGI,PTGES3,TP53,JPH4,ACTR1A,GRAP2,CCNF,STUB1,CTNNA1,GSK3A,CSNK2B,UBASH3B,VIRMA,SRC,RAB2A,PYCR2,PTPN11,SEC13,AP2A1,INPPL1,RPA3,SQSTM1,KDM1A,MRPL41,PIK3R2,GABARAP,VPS28,MRPL10,CDC42,CFTR,RPA2,UBE2M |
| 4.331e-06 | -12.35 | BNIP2 (BCL2 interacting protein 2) | protein interactions | 663 | 73 | 39 | 19454 | 5460 |
FAHD1,SEC61B,SYT2,CYB5R3,SIN3A,TMEM237,ERLIN1,FATE1,RAB11A,PLEKHO1,APOBEC3B,MYC,CREB3,MOV10,ATG9A,EI24,DHRS1,MYO6,LAMTOR1,FAS,DESI2,YIF1A,RAB5A,TMX2,SLC39A9,STX7,SFT2D2,RAB3B,SLC7A14,CDC42,ARHGAP1,ATG16L1,OTX2,ABHD4,FAM3C,SLC35E3,HEXB,FGFR1,LMNA |
| 4.339e-06 | -12.35 | positive regulation of cellular component organization | biological process | GO:0051130 | 1122 | 398 | 18204 | 5365 |
S100A10,TBC1D24,EMILIN1,IL1RAP,TAPT1,HRAS,PYCARD,ZNF304,CCT8,LRRC24,MBL2,STUB1,MAPRE2,CORO1C,RGS2,PTK7,VPS28,HFE,EPHA2,INO80C,CXCL12,MSX1,SLC25A4,FCGR2A,TMEM106B,RPS3,SLAIN2,LRRTM2,RUVBL1,H1-1,TNF,ROCK2,PPT1,MUL1,CX3CL1,CLDN3,ARF6,PIP4K2C,TENM3,MIEN1,DDR1,MIR17,LMAN1,NEFL,TBC1D5,CNTN1,TPPP3,RAB31,ASIC2,SLC25A5,RB1,CTTN,ADNP,LRRC4B,ATAD1,SH3GLB1,CRBN,CCL11,ENC1,DLG4,TRIM27,TLR4,TFPT,CRABP2,RAC2,FGFR1,HSPA8,SGIP1,MIR1-1,CLEC7A,SCN1B,ITGA6,EHD1,NEK7,SDC4,LPAR1,TNFSF10,MIR133B,SDCBP,TMEM30A,TP53,DSTN,CLSTN3,CXCL13,SFRP4,STK24,CDKN1B,MAPRE1,PRKCQ,B2M,CAPG,FAF1,EZH2,ADCK1,ATAT1,TPBG,EPO,RAD21,LGALS3,APOC2,GPM6A,PIWIL2,CCR7,TPPP,ISG15,VPS4B,SEMA5A,WASF3,ADRB2,GREM1,PROX1,WASL,PTPN22,ADD1,NCK1,IL2RG,TF,SMC4,OSBP,FCN2,IL1A,DUSP3,TGFB2,CBLN1,FIS1,BECN1,DLG1,CNOT6,MIR20A,GHRL,CCL21,CBL,SOX9,FEN1,MAP2K1,DRG1,RAP1B,FCGR1A,SUMO1,CLRN1,CD151,NCKAP1,IL5,MIR200C,PFDN2,CCT2,MACROH2A1,RIT2,ANAPC11,KDM1A,RETREG3,HSP90AA1,SYNDIG1,CSF2,WDR45,CDK5R1,PSRC1,PDCD5,MARCHF5,CDK1,EIF5A2,SSBP1,APLN,SFRP1,IGF1R,FERMT2,LRRTM3,CDC20,CDC42,FCHSD2,G3BP1,ZDHHC15,HNRNPA1,CDC16,IL2RB,EPHA4,CLDN1,FAM98A,CBLN2,PSEN1,TNKS2,PTN,AP2A1,CRB3,RUNX1,NPTN,IL4,MYD88,TACR1,SNX3,CD28,FKBP1B,MAD2L1BP,SWAP70,RUVBL2,MSTN,CAV3,EFNA5,AP2M1,KCTD17,SEPTIN7,CAV1,MCOLN1,TYROBP,USP8,MAVS,ARPC2,TNKS,HDAC6,FCGR2B,POLDIP2,STAP1,STK11,TMED9,CLU,SYK,RALB,RAP1A,SLITRK2,TRIM32,HNRNPD,CNOT6L,TFRC,ALKAL1,CD63,SMAD3,LRRN1,CCL19,PICK1,SFTPD,LRTM2,FEZ1,CDC42EP3,XRCC5,NEK2,MIR222,NLGN2,MIR183,FUT9,TESK1,IL15RA,P3H1,CCL2,DISC1,NUP62,PML,MAPKAPK5,CBLL1,FASLG,HNRNPK,THY1,STX18,HNRNPA2B1,EPS8,FAM162A,SERPINI1,NEGR1,ANGPT1,CALY,SRC,DAG1,SURF4,P2RY12,ROCK1,RAB8B,TOM1,PIK3CA,TIAM1,CD47,PAFAH1B1,IFNG,NLGN1,CDC23,CAPN2,CCT5,FZD4,NTRK2,STMN2,FLRT2,TCP1,NTRK3,ACTR2,NBN,CAMK1,SHOC2,CUL3,PIK3R1,AMIGO1,VEGFA,SEMA7A,BMPR2,NF2,IL15,NFE2L2,FBXO7,MECP2,SLITRK1,TLR6,INO80E,SMAD4,ITGA2,DRD3,CCT7,WNT7A,PPP3CA,ELAVL4,TGFB3,IL1B,NDNF,NPR2,MAP1B,BAK1,CTNNB1,GH1,RALA,GPX1,TOX,OXTR,CCL24,CNOT2,DKC1,EP300,IGF1,CALR,BOK,SNX18,ATP5IF1,MIR221,CNR1,MSN,AR,RND2,SOD1,MET,CDC42EP2,FLRT3,KIT,MLLT11,CD14,GSK3A,PRKCE,L1CAM,DVL2,RAB27A,ATF1,LCP1,BAD,RGMA,TSG101,ATP8A1,TIRAP,PLA2G5,NRP1,PCSK9,PKIB,VLDLR,NR1H2,CAND1,IQSEC1,NEUROD2,CLIP3,FLOT1,SLX1A,HAS3,PLXNC1,NCKIPSD,MORC2,ACTL6A,VDAC1,IL6,SLITRK5,BAX,MIEF1,CFL2,MMP9,G3BP2,LRRTM1,CXCL9,FCER1G,ANAPC2,MSX2,PPP1R10,MIR21,SMURF1,PLCB1,RGCC,UBE2B,GPRASP3,CD36,CDC42EP4,PMAIP1,NCAPG2,MNS1,LYAR,MAD2L2,GPR65,TPPP2,WNT10B |
| 4.349e-06 | -12.35 | Chemokine_IL8-like_dom | interpro domains | IPR001811 | 45 | 28 | 18521 | 5414 |
CCL24,CCL1,CXCL13,XCL1,CXCL9,CCL2,CXCL3,CCL25,CCL8,CXCL8,CCL18,CXCL10,CCL11,CX3CL1,CCL27,CCL3,CCL19,CCL17,CCL28,CCL23,CXCL1,CXCL14,CCL4L1,CCL20,CCL5,CCL21,CXCL11,CXCL12 |
| 4.349e-06 | -12.35 | Interleukin_8-like_sf | interpro domains | IPR036048 | 45 | 28 | 18521 | 5414 |
CXCL1,CCL28,CCL23,CCL5,CCL21,CXCL11,CXCL12,CXCL14,CCL4L1,CCL20,XCL1,CXCL9,CCL2,CXCL3,CCL25,CCL8,CXCL8,CCL24,CCL1,CXCL13,CCL18,CXCL10,CCL11,CX3CL1,CCL27,CCL3,CCL19,CCL17 |
| 4.391e-06 | -12.34 | MAP4K1 (mitogen-activated protein kinase kinase kinase kinase 1) | protein interactions | 11184 | 128 | 60 | 19454 | 5460 |
IRF3,SOD1,PYM1,MAVS,SQSTM1,FBXW7,NF2,SKP1,SYK,NDUFA5,PIH1D1,CSNK2B,EIF2S2,HDDC2,MAGOHB,POLR2B,PPP5C,SLC25A1,RPS6KA4,DNAJC10,CCT2,MRPS16,THTPA,HSP90AA1,CCT8,MAP3K11,HSD17B10,RPAP3,THRAP3,PRPS1,PTGES3,RIGI,TMEM101,CCT5,TBK1,UCK2,PDHA1,CRKL,SPRY1,MLLT11,GRAP2,PPP4C,ALPL,PHB1,RPL32,HCLS1,WDR6,TCP1,SPPL3,HSP90AB1,CCT7,LCP2,NKIRAS2,COPS5,NCK1,FKBP4,SHC1,H2AC4,HAX1,VPS4A |
| 4.401e-06 | -12.33 | positive regulation of type I interferon production | biological process | GO:0032481 | 75 | 41 | 18204 | 5365 |
TRAF3IP3,OAS1,CGAS,POLR3F,NMBR,TRIM15,MAVS,POLR3B,STAT1,TLR3,GAPDH,KPNA2,G3BP1,RIGI,TICAM1,IRF7,TLR7,TANK,TLR4,FLOT1,TBK1,HSP90AA1,PTPN11,IRF3,ISG15,TOMM70,TLR8,UAP1,TICAM2,DHX9,TRAF6,IRF1,MYD88,CD14,PQBP1,HSPD1,TLR2,PTPN22,IFIH1,TLR9,SYK |
| 4.406e-06 | -12.33 | NSFL1C (NSFL1 cofactor) | protein interactions | 55968 | 161 | 72 | 19454 | 5460 |
PRMT5,PHAX,MSN,CCNF,SH3BGRL,IDE,UBA3,RPL22,VCF1,GMDS,TENT5C,FBXO7,UFD1,TUFM,PPP1CC,PSMB2,MYC,SFN,CUL3,CUL2,BAX,OAT,CCT2,MYO6,RPA3,PEBP1,BAP1,PXMP2,PSMC1,DNAJC22,PPP1R2,KDM1A,STAU1,GPC1,RND2,CDC42,CDK1,PLAA,RPA2,MCL1,STX5,SRP14,DIRAS3,LMAN1,NUF2,DHX15,SPPL3,PRNP,SPTAN1,RHOH,CTNNB1,UBXN6,VCPIP1,MED4,PPP1R11,UBXN10,RHOG,FAF1,NAE1,PSMD12,SEM1,NEDD8,KRAS,UBXN2B,ISG15,KIF2A,ANP32A,KBTBD4,MTCH2,CAPN2,RHOBTB1,EZH2 |
| 4.440e-06 | -12.32 | Adaptive Immune System | REACTOME pathways | R-HSA-1280218 | 810 | 312 | 10285 | 3229 |
PRKCB,FCGR1A,CALR,PSMD12,ICAM3,AKT2,ICAM1,RNF41,FGF3,FCGR2B,TRAF6,RNF126,PSMB9,WSB1,FBXW7,BAD,GSK3A,GRAP2,DYNLL1,HCST,CD274,UBE2M,FBXL14,FBXO44,MYLIP,SNAP23,CDC16,TRIM63,AHCYL1,PSMB1,CD3G,CDC20,CD81,PSMC4,PSMA4,DCTN3,KLRD1,PDCD1,LY96,PSMB11,FGFR1,SEC61B,UBE2E3,PSMB6,PSMA2,RNF34,ZBTB16,ASB8,CUL2,UBE2B,PSME1,NCK1,CD34,LILRA2,TRAF7,PSMD14,UBE2L3,HECTD1,UBE2G2,SIAH2,PTPN11,CD40,UBE2F,LILRB4,PPP2R1A,LCP2,UBB,BCL10,TAB2,CTSD,DYNC1I1,JAML,PSMC1,CUL3,ACTR1B,PPP2CB,SMURF1,HRAS,KIF2A,UBE2V1,TAPBP,PSMB2,PSMD1,PIK3CA,AKT1,RASGRP3,SHC1,IKBKB,TLR2,SEC61G,CDC23,CTSK,PAK2,SEC22B,CTLA4,AP1S2,PSMA1,KLHL22,ITGAV,PSMD4,FBXO31,TRIM21,PIK3R2,DET1,AREL1,SOCS3,TRPC1,FGF1,SELL,TREML1,HUWE1,MET,NFKB1,RNF115,SIAH1,FBXW4,PTEN,UBE2H,PIP5K1A,ANAPC13,KLHL3,KIF3C,CD200,PSMD10,LILRB1,CD36,RBCK1,FBXL19,MOV10,TLR1,CD79B,HECTD3,KRAS,STIM1,VAMP8,FGF22,SYK,ASB1,RAF1,TNRC6C,NFKBIB,CTSA,CD4,HERC3,CDKN1A,PIK3R3,ICAM2,FGF7,TIRAP,NCR3LG1,AP2S1,WWP1,UBE2V2,RACGAP1,KLHL9,FBXO22,HERC4,AP2M1,RAP1A,STUB1,DCTN6,PSME2,UBE2D1,SIGLEC5,HBEGF,PSMD6,ANAPC2,TRIM36,PTPN22,FZR1,MYD88,LILRA1,KLC2,KBTBD6,RLIM,RNF7,UFL1,RNF182,PSMB7,FBXO32,CREB1,PSMD3,LILRA3,CD1C,PIK3R1,TRIM32,CLEC2B,PSMB5,PSMA3,CDKN1B,UBE2W,DNM2,B2M,PSMB10,PSMC5,TYROBP,UBE3A,SEC61A2,ITK,FBXW11,CTSC,CSK,CD28,FBXL7,AGO1,UBA3,SKP1,CD40LG,ASB11,ORAI2,FGF17,CD80,NECTIN2,PSMD7,CD1B,TRIM11,UBE2A,ELOC,PRKACB,TLR4,CDC26,CBL,PDCD1LG2,AP1M1,MAP3K14,FGF16,RNF144B,FBXO30,SPSB1,ASB3,IER3,UBE2N,SEC61A1,PDIA3,FBXL4,KIF3B,CCNF,CD1A,KIT,GAB1,PIP4K2C,RNF14,ZNRF1,CD1D,MADCAM1,UBE2K,AKT3,PSMA6,FBXO7,ITGB5,SEC23A,PSMB4,CD14,SEM1,ACTR1A,ANAPC4,PSMC3,TP53,UBE2D3,CD86,BTN2A2,RPS27A,HSPA5,ANAPC11,UBE2E2,ARF1,ICOS,YWHAB,CDC42,MDM2,DYNC1I2,PPP2R5A,TLR6,KLHL25,SAR1B,PSMA5,FGF23,PPP2R5E,KLRF1,SH2D1A,AP2A1,YES1,NCR3,CD247,ASB7,PSMB3,DCTN4,FBXL3,MICB,TRIM37,RCHY1,SRC,FBXO9,KBTBD13,PIK3AP1,VAMP3,FGF10,CD200R1,NFKBIA,YWHAZ,RAP1B,PRKCQ,TNFRSF14,SEC13,UBE2S,CTSB,CD209,UBA52,CD226,RASGRP2,ATG7,MRC1 |
| 4.465e-06 | -12.32 | SEC24C (SEC24 homolog C, COPII coat complex component) | protein interactions | 9632 | 192 | 83 | 19454 | 5460 |
ALYREF,EED,PBDC1,CYB5A,SEC23A,CAND1,RAB1B,HSP90AB1,CDC5L,MOV10,ERCC3,WWP2,RAB5C,XPO1,CTNNB1,SPP1,H2AC4,TRAPPC2L,DNAJC4,HNRNPD,DNAJC7,ZYX,RAB1A,MAP1B,SLC39A7,EWSR1,YIF1A,IGF1R,PSMA5,G3BP1,SSRP1,RIGI,AHCYL1,SAR1B,CPLX1,RAF1,TP53,SUPT5H,PPIL3,OTUD6B,EZH2,VPS33A,TRAPPC13,CCNF,ARF1,OPTN,B4GALT1,MSN,PTEN,MAGOHB,GGPS1,ESR2,DYRK1A,RAB2A,MYC,CUL3,SEC13,PSMD1,FBXO7,SLC30A5,BRCA1,IGF2BP1,CRMP1,SERPINH1,UBE2H,HERC4,RPA3,SLC39A9,SIRT7,HSPA8,EP300,MIA2,UNC45A,NOTCH2,FUT8,CD2AP,CDC42,CFTR,RPA2,CTBP1,PICALM,UBE2M,PIH1D1 |
| 4.512e-06 | -12.31 | cell body | cellular component | GO:0044297 | 556 | 210 | 19108 | 5553 |
TLR2,HPCA,CRHBP,PPT1,CYP17A1,BMPR1B,TGFB3,SMURF1,PSD2,CSNK1E,NDN,SIAH2,DISC1,CCR2,SST,HDAC6,DRP2,INHA,BRINP1,RIC3,TNF,ENO2,STMN2,ADNP,P2RY12,TACR3,GABBR1,P2RY1,KCND3,CPLX2,TACR1,TMEM100,PYCARD,CX3CR1,AZIN2,ATP1A3,GABRA2,GPM6A,EPHA4,KLHL24,ROGDI,NCDN,PNOC,SNCB,GLRA1,VTI1B,SLC12A2,PPP1R1B,HSP90AA1,KCNB1,SNAP25,HTR2A,EIF4A3,G3BP1,ADORA1,TGFB2,GLUL,ATP1A2,TIAM1,CCR4,PICALM,CCT7,CAPN2,LYPD6,EFHC1,PSEN1,RPL28,GNB4,SLC38A2,SERPINI1,SNCG,KCNA2,CYGB,TXNRD2,CRMP1,MAP1S,OPRM1,TOP1,RGS7BP,ATXN10,NEGR1,ENC1,SLC2A3,NRSN2,CDC42,KCND2,LRP6,GJB2,PDYN,CCT2,BMPR1A,KLHL1,LPAR1,SLC6A1,SLC1A3,MAGOHB,IGF2BP1,GNB3,GSK3A,IGF1R,UBB,S100B,MIR107,GRIA1,UCN,SOD1,CCN3,CCT5,FKBP4,RAB5A,GHR,SLC1A2,GRIA2,BMPR2,CCT8,PTK7,AKAP12,CRYAB,FEZ1,SRC,SLC38A7,L1CAM,HOMER1,ZC4H2,CX3CL1,ASTN1,STAU1,SLC1A1,PDE1B,KCNJ2,CDK5,CD200,SLC38A1,MAP1B,IL6ST,GLRX5,MOB4,MUL1,GNAI2,BGLAP,KCNH1,TMEM266,ELK1,RRM1,PAFAH1B1,UPF3B,NRSN1,FBXO31,PGRMC1,KCNJ10,GNAO1,FZD3,TMEM50A,NF2,NQO1,SLC6A3,BACE1,GAD2,ADAM21,TAC1,SLC6A2,PDE9A,HSPA8,KCNJ11,TUBB,ELAVL4,FBXW11,HTR5A,SLC25A27,SYT4,SLC6A6,PMM2,CDK5R1,ACTA2,SYNDIG1,ALCAM,KCNC1,EPO,GNG3,FCGR2B,THY1,PHAX,BRINP3,TCP1,PPP2R1A,YKT6,OPRK1,ASIC2,CD40,C9orf72,SMN1,PDE1A,MME,SRSF10,AMIGO1,SLC4A10,GLRX2,PCSK2,FUBP3,CPLX1,HSP90AB1,TNFRSF1B,GNAZ,SLC4A8,BRINP2,RIT2,PACRG,RCVRN,SLC8A1,SCN1B |
| 4.529e-06 | -12.31 | CDC40 (cell division cycle 40) | protein interactions | 51362 | 120 | 57 | 19454 | 5460 |
RPA2,LSM2,MFAP1,SF3A1,WDR83,SNRPN,RALYL,STAU1,SAP18,SNRPA,SNAPC1,DDX39B,NKAPD1,SF3B1,EP300,CCT2,ELAVL2,SMAD2,PFDN2,MYC,HNRNPC,SNRPB,SNRNP40,SMURF1,SNRPB2,ESR2,EIF4A3,ILF2,SNRPE,NUPR1,RAF1,DHX38,PPP2R1A,TRAF2,TSSC4,CTNNBL1,NUP42,SNRPG,SNIP1,ZC3H11A,SRSF7,RTCB,KIAA1143,CHCHD1,MAGOH,PRPF19,IFI16,MOV10,ZCCHC10,FZR1,SNRPA1,SNRPD3,TOP1,MIRLET7G,CCT7,CDC5L,MIR106B |
| 4.529e-06 | -12.31 | DERL2 (derlin 2) | protein interactions | 51009 | 120 | 57 | 19454 | 5460 |
SNX1,MPP1,ARL6IP5,HSP90AB1,OS9,STT3A,PTPN1,KRT8,RAP1B,ESYT1,POR,P2RY1,FXYD6,SELENOS,EDEM1,CCR6,ERLEC1,TNFSF8,VTA1,ATP5PF,EMC2,LPAR2,PDHA1,SERPINA1,CRELD1,CCDC47,FAF2,MGARP,SNX3,RAB14,B4GAT1,APLNR,CYRIB,S1PR4,GPR173,SEC61A1,RETREG3,HEY2,SRP54,EXOC8,CUL3,CUL2,GPM6A,LPAR1,HSCB,EMC1,TTR,RNF5,TSPAN15,RAB5A,RTN4,DERL1,SYVN1,VIPR1,GPR35,LMNA,CFTR |
| 4.531e-06 | -12.30 | HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13) | protein interactions | 345275 | 139 | 64 | 19454 | 5460 |
TMEM14B,TMEM31,VAMP2,NRM,SPG21,YIPF4,INSIG2,SACM1L,SFT2D2,TF,TMEM60,UNC50,SFXN1,RUSF1,ADGRE2,TMEM42,SCAMP5,ORMDL3,FATE1,TSPAN10,TMEM19,SLC25A46,MARCHF5,LRAT,AIG1,TMEM97,ANKRD46,STX5,RAP1B,MFSD5,RPRM,CMTM7,MMP14,VAPB,TIMM23,CCDC167,PLP2,SEC22B,TIMMDC1,AGTRAP,GOSR2,CLDN4,STX7,TMEM167B,TMEM243,TMEM203,RABAC1,JAGN1,RHOU,TMX2,REEP6,TMEM100,SLC35E4,FAXDC2,PLN,SLC35B4,GJB2,VAMP5,TMEM229B,SFXN2,CYBC1,CYB5R3,CDIPT,VAMP3 |
| 4.531e-06 | -12.30 | ZBTB48 (zinc finger and BTB domain containing 48) | protein interactions | 3104 | 139 | 64 | 19454 | 5460 |
APEX1,RPS9,PRKRA,RPS3,H1-1,RRP7A,NSA2,ILK,PTTG1,FTSJ3,BRCA1,ZCRB1,MRPS25,CEP70,ZSCAN25,FBXO7,RPF2,MRPS7,UTP23,RGS2,RPS15,DGCR8,EP300,ZBTB6,HIRA,DVL2,RPLP0,RPL26L1,SDC2,MRPS34,APOBEC3C,CDKN1A,NOTCH2,SURF6,NCBP2,DKC1,LYAR,PRNP,MAP1LC3A,RPL32,SDC4,SRP14,MRPS9,CDC23,MRPS26,TNFRSF14,INO80E,MRPS35,RPL17,MRPS18C,CDK2AP2,MRPS33,MRPS11,RPL23A,FBXO11,MRPS18B,RPL3,ZBTB26,RBM34,EZH2,THAP1,MAK16,MAGEB10,TPD52 |
| 4.533e-06 | -12.30 | EIF3F (eukaryotic translation initiation factor 3 subunit F) | protein interactions | 8665 | 279 | 113 | 19454 | 5460 |
EIF4E2,SRP14,FZR1,MSMO1,TMPO,DKC1,SLC25A17,USP3,CSNK2A1,COPS5,CD81,HDAC6,MAP1B,ABCE1,RAB27A,HNRNPK,HUWE1,EIF4EBP2,EIF3E,MEPCE,TP53,EEF1A1,JOSD1,TUBA1B,ALB,RTRAF,CSNK2B,VIRMA,UQCRQ,SUB1,NONO,USP14,RC3H2,EIF3G,COL1A2,UBE2H,ATP1A1,PML,BAP1,RPA3,FBXW7,GTF2I,CLU,AATF,EIF4E,ATG16L1,EIF3J,CFTR,MAEL,CDC42,RPA2,FBXO32,KRT8,ATP6V1A,HSP90AB1,WWP2,IFI16,EIF3D,HNRNPA1,PPIB,AGR2,SMAD9,HAX1,DDX1,G3BP1,RAD21,UBE2A,SUPT5H,HTR2A,GTF2E2,KIF2A,TUBA1A,ACTN4,SOX2,CHMP4C,TUBB4B,GLE1,EZH2,CSTPP1,HGS,RPS11,EIF3K,MCPH1,PRMT5,ACTB,TUBB,EIF4A2,BTG3,RABIF,PRRC2A,ESR2,RPL10,CUL3,MYC,BTF3,NLRP3,HSP90AA1,ICAM1,HTR1A,DDX5,RAB5A,EP300,HDAC5,HSPA8,EIF1B,PTN,UFL1,G3BP2,CDSN,COIL,NDE1,TIMM29,EIF4B |
| 4.543e-06 | -12.30 | membrane fusion | biological process | GO:0061025 | 157 | 73 | 18204 | 5365 |
CHMP1B,VAMP8,NSFL1C,ROPN1B,STX1A,NAPG,SEC22A,VPS33A,NECTIN2,STXBP6,STX11,STX18,VPS39,SNAP25,STX16,SERPINA5,HUWE1,STX8,SNAP29,FOLR2,CHP1,VCPIP1,VAMP1,LYZL4,STX5,VPS4A,CLTRN,YKT6,VAMP7,GOSR1,CHMP1A,TOM1,GCA,STX10,GOSR2,SEC22B,HYAL2,VPS16,STX12,USE1,CHMP5,IZUMO1R,SNAP23,STX6,RABIF,CD9,BET1,YIPF4,BET1L,YIPF5,DPP4,CRISP1,CHMP4C,VAMP3,NAPA,SYT4,STX17,STX7,PLA2G5,CAV2,CHMP2A,FOLR1,TMEM95,VAMP2,STXBP1,LYZL6,VTI1B,IZUMO1,UBXN2B,VIPAS39,SNAPIN,VPS18,CHMP2B |
| 4.574e-06 | -12.30 | Rab5c (RAB5C, member RAS oncogene family) | protein interactions | 19345 | 112 | 54 | 19454 | 5460 |
COX6B1,ABCG2,STX10,RMDN3,VDAC2,CCNF,CHCHD3,GMDS,UQCRC1,SLC35E1,RAB37,SEC22B,SLC35F6,STOM,UBAC2,JUP,VAPB,TMUB1,PIP4P1,CHMP2B,ATAD1,PHB2,GOSR1,RNF5,NDUFV2,RAB5C,STOML2,PDIA3,TMEM199,ATP6V1A,STX5,PHB1,CCDC127,NDUFB4,CHMP2A,CAV1,SLC38A2,ERLIN1,COG1,RPS10,SPRR1B,ERLIN2,NDUFA2,MACO1,NDUFA12,TMEM165,GDI2,NDUFS6,TFRC,CYBRD1,FLOT1,FKBP8,GALNT2,VDAC1 |
| 4.574e-06 | -12.30 | NFRKB (nuclear factor related to kappaB binding protein) | protein interactions | 4798 | 112 | 54 | 19454 | 5460 |
ACACA,KLF3,RPA2,ACTL6A,COIL,GSTT2B,GTF2I,RPA3,PML,NLE1,XPOT,HSP90AA1,CAV3,AR,VPS39,HNF1B,MYC,EMILIN1,IFI35,CIAO1,CUL2,DDAH2,ESR2,SNRNP40,MANSC1,ACTB,CSNK2B,TMEM74,PSPC1,TNFRSF1B,PSMC3,CBX3,CTLA4,EGR2,ELF1,KBTBD4,SUPT5H,TP53,PRPS1,PAX6,TRIM37,ASF1A,RUVBL1,EWSR1,INO80C,RUVBL2,BAG2,TFPT,BRD3,BCL7C,NFKB1,INO80E,RPS16,SPINT2 |
| 4.576e-06 | -12.29 | protein stabilization | biological process | GO:0050821 | 214 | 94 | 18204 | 5365 |
CCT5,TCP1,RPL23,RTN4,CDC37L1,PIK3R1,UBE2B,CREBL2,STX12,HSP90AB1,PIM2,RUVBL2,HYPK,TYROBP,PFDN6,PYURF,WNT10B,TRIM44,GAPDH,GOLGA7,HSP90AA1,ZBED3,PHB2,STK3,DNAAF10,FLOT1,PTGES3,PPIB,HSPD1,BAG2,GPIHBP1,PRKRA,LAMP2,CREB1,ATP1B3,USP2,CRYAB,CAMLG,ZSWIM7,GNAQ,ZNF207,RPAP3,TP53,EPHA4,STK4,H1-5,ATP1B1,CDK7,CTNND1,CSNK2A1,CCNH,DNLZ,BAG3,TMEM88,PIH1D1,SYVN1,SUMO1,P3H1,STXBP1,PTEN,CCT2,PFDN2,TTI2,TESC,RPS7,FBXW7,CCT8,MCM8,PDRG1,CCT7,STUB1,CLU,TRIM37,USP13,RABL3,NAPG,SAV1,NOP53,MSX1,CRTAP,TAF9,PHB1,MT3,RUVBL1,PDCD10,NAA15,IGF1,EP300,MUL1,CALR,MIR101-1,CHP1,NAA16,SMAD3 |
| 4.591e-06 | -12.29 | MTRF1 (mitochondrial translation release factor 1) | protein interactions | 9617 | 241 | 100 | 19454 | 5460 |
MRPS16,TYW3,CSK,NDUFAF2,PYCR2,YES1,MRPS28,ACAT1,MRPL53,VAMP3,EIF2AK2,QRSL1,MRPS34,MRPL10,MRPL20,POLDIP2,PDHB,NME4,MRPL17,MRPL40,MRPL41,TWNK,GFM1,DLAT,TRMT5,GRSF1,MOV10,COX5A,DBT,MRPL24,MRPS23,MRPL50,MRPS9,MRPL51,MRPL49,NDUFS3,PPIF,BCS1L,ATP5PB,NDUFA2,TP53,MRPL47,MRPL22,FASTKD5,MRPS18C,MRPS33,PDE12,HSPE1,MRPS18B,THG1L,ATP5PF,NOA1,MRPS25,RHOB,MRPL16,FMC1,PYCR1,HNRNPAB,PMPCA,NDUFAF4,MRPL23,ATP5F1B,TRMT11,MRPL13,TACO1,DLST,NDUFA5,MRPS18A,MRPL12,MRPS7,NDUFS2,HADHA,MRPS26,ASB7,MRPL18,MRPL9,NDUFV2,CLPX,STOML2,MRPS35,NDUFS8,HNRNPL,LYRM2,GATD3,KRT8,MTMR2,NDUFA12,PDHA1,NDUFS6,HSDL2,LYPLA1,ETFB,RPS27A,MRPS17,HNRNPDL,ETFA,KGD4,HINT2,MRPS11,PREPL |
| 4.625e-06 | -12.28 | HSPA14 (heat shock protein family A (Hsp70) member 14) | protein interactions | 51182 | 91 | 46 | 19454 | 5460 |
RELL2,DNAJC2,STIM1,GPX7,TAB2,E2F4,RAF1,ATP5PB,KDM4B,KRAS,FKBP8,DRG2,SMAD4,DRG1,UBXN6,PDIA3,MZT2B,HYPK,TRIM35,WIF1,SURF6,FBXO32,EEF1AKMT3,CYB5A,LDLR,RWDD1,PCLAF,RPA2,WRAP53,MTF1,CFTR,SNRNP27,HSCB,LGI1,DNAJC3,RPA3,BRCA1,SPOP,FAS,UBE2H,DNAJB6,FAM107A,DNAJC5,USP14,LMBR1L,POLR3H |
| 4.625e-06 | -12.28 | DAD1 (defender against cell death 1) | protein interactions | 1603 | 91 | 46 | 19454 | 5460 |
HSD11B1,EED,MCL1,STT3A,TMPO,FAM241A,CTNNB1,CCR6,ICAM2,SYNJ2BP,RB1CC1,PDCD1,POR,SMAD4,LDLRAD4,FKBP8,TUSC3,SRPRB,VDAC1,KRAS,TP53,CCDC47,CFAP68,RAF1,RPN1,SLC1A1,LMBR1L,ESR2,TOMM40,TIA1,GPBAR1,TMED5,OST4,RAB2A,RIT1,TYROBP,HSPA8,RPA3,LRRTM2,ADRB2,HSCB,PGRMC1,TMEM231,GPR35,PICALM,RPA2 |
| 4.631e-06 | -12.28 | ELAC2 (elaC ribonuclease Z 2) | protein interactions | 60528 | 178 | 78 | 19454 | 5460 |
MTRES1,RPA2,CTBP1,DDX5,GFM1,HSPA8,AMACR,EXD2,RPA3,NGRN,CRYZ,HSCB,TUFM,GORASP2,PMPCA,PYCR1,AUH,MTG2,MYC,UBE2H,RIT1,SNX5,SMAD2,CCDC90B,MTG1,TACO1,OPTN,VIRMA,TNPO3,MYG1,FERMT2,TSN,TAX1BP1,METTL15,AURKAIP1,GLRX5,MRPL11,TBK1,TOP3B,FEN1,GFM2,PDHA1,BAG2,HSD17B10,COX8A,RING1,HINT2,HSPD1,FKBP8,EIF2D,PFDN1,FASTKD5,HNRNPK,DNAJC30,HNRNPF,KRAS,COPS5,PFDN5,GRSF1,MTRF1,DNAJC7,MRPS26,CHCHD1,SNRNP70,GATD3,YBEY,XPO5,COX4I1,PHB1,FBXO32,PPP2CB,AIFM1,SMAD3,SSBP1,CEP19,RMND1,MALSU1,SUMO2 |
| 4.631e-06 | -12.28 | DICER1 (dicer 1, ribonuclease III) | protein interactions | 23405 | 178 | 78 | 19454 | 5460 |
STAU1,DUSP26,HSCB,EIF4E,NOG,SIRT7,RPL27,RPA3,RNF113A,RPA2,RPLP0,SEC22B,RPL27A,TIMM13,AGO1,RPP25L,RPL13A,VIRMA,MAD2L2,DUSP10,RPL10,SFRP4,EIF2AK2,FBXL14,CCNF,ALB,PTPMT1,PIWIL3,GSK3A,PRKRA,RIT1,DNAJC19,UBE2H,PIWIL4,CFAP20,RPL7A,CUL3,ZMAT3,PIWIL1,KRAS,MSH6,IMMP2L,LECT2,RIGI,SMN1,PIWIL2,PHF1,PPAN,DHX9,RPL3,SIX5,DNAJC2,HDAC11,AAMP,ILF2,CENPM,STRBP,RAF1,DIPK1A,TULP3,RPL15,EMILIN3,ANAPC13,HSP90AB1,CEP19,EGLN3,PTP4A3,RCHY1,SYNCRIP,RPL12,RPLP2,RPLP1,RAP1B,RPL10A,DICER1,RPS2,HNRNPD,MOV10 |
| 4.638e-06 | -12.28 | NEDD4 (NEDD4 E3 ubiquitin protein ligase) | protein interactions | 4734 | 494 | 184 | 19454 | 5460 |
HGS,ERRFI1,FOXJ3,ISG15,CRTC2,VDAC1,RUVBL1,IFNG,NFE2,CDK5,LDLRAD4,RPAP3,YWHAB,PRKX,SIVA1,LAMP2,STK4,YWHAG,XPO1,YWHAH,PPIB,SUMO2,HNRNPL,SLC38A3,HSP90AB1,TNIK,FABP5,LAPTM4A,PIP4P2,ZC3H14,SYK,TOM1L2,ADRB2,RER1,UBE2D3,TRIM52,RANBP10,BMPR1A,PEBP1,PYM1,DDX39B,ARRDC3,RAP2A,STK26,EP300,RPS6KA4,CKB,GFUS,NDFIP1,ATP5F1B,PSMD4,APEX1,POLR2B,TRIM44,DDIT4,VDAC2,GUCD1,SFTPC,SPRY1,RPSA,TMEM252,ESS2,RPAP2,HNRNPK,RBCK1,LRP3,FGF12,CAPZA1,ILDR1,BECN1,AQP2,PGAM1,TPM3,MIF,CD274,FGFR1,SLC22A8,TCP11L1,RPRD1B,RPA2,KCNAB1,UBE2M,MYCT1,CFTR,CCNH,LITAF,TUSC2,PIP4P1,MAPKAPK3,PGK1,AKT3,AKT1,MAP3K3,SRC,SMURF1,CALML5,EZH2,POLR2C,CDK5R1,ANP32A,RAF1,GABARAPL1,JUN,ANP32B,HNRNPA2B1,PLSCR1,SRSF7,KDM2A,UBE2D1,CDIP1,SAV1,PDIA3,HMGA1,HNRNPA1,DNM2,TSG101,GJA1,MAP1LC3A,RNF7,ABCB1,PPARG,TMEM174,IL2RG,CDKN1A,PRDX3,IL1B,SKP1,RNF11,TGFB1I1,WBP2,ATP5IF1,YWHAZ,GRB10,PRDX2,SUSD6,ENO2,SLC23A2,GRIA1,CPSF1,AP1G2,TBK1,SMAD1,MAP1LC3B,THRAP3,TOM1,HSPE1,SERTAD1,EGR1,IGF1R,SLC6A3,PROM1,CLIC2,CALR,THOC1,CGAS,DCUN1D1,CAV1,MDM2,SMAD3,HSP90B1,PIP5K1A,GABARAPL2,PRRG1,GABARAP,NHP2,SOD1,SQSTM1,HMCES,SLC22A6,STK24,TMEM255A,SMAD2,IL2RB,RUNX1,YES1,SMAD5,VIRMA,UBE2L3,UBB,ENO1,CCNF,UBE2I,PTEN,SLC11A2 |
| 4.639e-06 | -12.28 | MRPL1 (mitochondrial ribosomal protein L1) | protein interactions | 65008 | 195 | 84 | 19454 | 5460 |
SLC30A7,RPS20,MRPL13,TACO1,MRPL53,MTG1,RPL19,RPL10,MRPL23,RPL13A,MRPL16,RPL26,TUFM,MTG2,MYC,AUH,PMPCA,CUL3,IGF2BP1,PTTG1,CIRBP,RC3H2,MRPL34,DLAT,GFM1,NGRN,MRPL20,MRPS7,HSCB,MRPL17,MRPL57,MRPL41,MRPL40,MRPL10,RBMS2,MRPL12,RPL27A,MTRES1,MRPS18A,CORO1C,PRR3,GATD3,SSBP1,COQ8A,RPL12,MRTO4,ALYREF,MALSU1,CAND1,FZR1,HNRNPL,MRPL50,MRPL9,HNRNPA1,MTRF1,RPL6,HNRNPD,MRPS26,MRPL18,RHOG,TMEM70,CHCHD1,SNRNP70,HINT2,RPL3,SETD4,SLC25A10,HSPD1,MRPL52,LSM14A,RBM3,FASTKD5,SRSF4,RPL17,NUP42,AURKAIP1,SOX2,METTL15,MRPL47,MRPL11,RANBP1,MRPL33,MRPL49,MRPL51 |
| 4.665e-06 | -12.28 | MRPS33 (mitochondrial ribosomal protein S33) | protein interactions | 51650 | 164 | 73 | 19454 | 5460 |
SRC,RPL10,RPL35,MED17,RPS9,CCDC90B,MTG1,TACO1,UBE2H,CDKN2AIP,MCAT,MRPS25,TUFM,RPL26,RIOK2,PMPCA,MYC,AUH,MTG2,MRPS7,CRYZ,NOP53,RPL4,HSCB,GFM1,EXD2,NGRN,RPL27,MTRES1,ZNF574,FGFR1,MRPS34,TMEM115,KLF12,RBMS2,MRPS23,RBM42,GATD3,TRMT10B,SRP14,SSBP1,MRPS9,MRPS26,NOL12,SNRNP70,CHCHD1,TMEM70,MRPL18,TRA2A,E4F1,RPL6,H2AC14,MTRF1,GRSF1,RPL17,MRPS17,FASTKD5,MEPCE,MRPS18C,SRSF7,MRPS11,RPL23A,HINT2,MRPS18B,HSPD1,RPL18,GFM2,METTL15,APOBEC3D,AURKAIP1,YIPF4,MRPL11,RAF1 |
| 4.684e-06 | -12.27 | positive regulation of proteolysis | biological process | GO:0045862 | 341 | 139 | 18204 | 5365 |
KHDC1,PYCARD,AGER,TANK,NKX3-1,GABARAP,FBXW7,S100A10,SNX33,S100A8,NOP53,CLDN4,TNFSF15,AIFM1,AKT1,IL1B,HMGB1,USP13,MIR205,PSMC1,SYK,GCLC,CLU,STUB1,NLRP1,RPS3,PSMC4,EGLN3,CYFIP2,TRIM32,CTSK,BAK1,ZFAND2A,SMAD3,PACSIN3,MUL1,BOK,ROCK2,DDRGK1,APH1A,VSIR,TNF,TRIB1,CTSD,HSPE1,CLDN3,PIAS1,FIS1,ATP5IF1,PSMC3,NLRP3,FAS,PSME1,ANP32B,MIR17,RGN,DAP,BAD,SUMO1,RGMA,NLRP2,CDK5RAP3,GSK3A,FBXW11,CRADD,BCL2L1,PSMD10,PSMC5,DISC1,SEMG2,JAK2,PTEN,FASLG,TRAF7,SOCS4,BAG2,SRC,HSPD1,BCL10,AURKAIP1,ENO1,HSPA8,SUMO2,PDCD5,FAM162A,PSENEN,CDC20,FZR1,DAPK1,MIR15A,NUPR1,ZER1,CSNK1E,BAX,RCHY1,MYC,CLEC7A,EPHA4,CTSC,IFNG,MMP14,EFNA3,ACVR1C,MDM2,SPON1,TNFSF10,CCDC22,PSME2,CSNK1A1,DNAJB2,MIR21,RPS27L,ARL6IP5,SGTA,PSEN1,IFI16,PPARG,IFT57,MCL1,HECTD1,HTRA2,TNFRSF1B,PLGRKT,SMURF1,SOCS5,COP1,CAV3,USP5,PMAIP1,FBXO22,NCSTN,TGFB1I1,PRELID1,BCL2A1,FURIN,RNF139,DET1,CAV1,NFE2L2 |
| 4.715e-06 | -12.26 | CHML (CHM like Rab escort protein) | protein interactions | 1122 | 56 | 32 | 19454 | 5460 |
MTCH2,RAB6A,SEC62,RAB6B,RAB4A,RPA2,RPN1,RAB29,RPA3,RAB1A,RAB5A,RAB9A,RABGGTB,RAB30,RAB27A,RAB3B,PSMA1,RAB8B,RAB5C,RAB11A,RAB2A,RAB32,LAMTOR1,RAB3A,RAB31,RAB35,SEC61B,RAB9B,RAB1B,RAB14,RAB11B,RAB33A |
| 4.720e-06 | -12.26 | Sm-like protein family complex | cellular component | GO:0120114 | 96 | 49 | 19108 | 5553 |
SNRPE,LUC7L3,PRPF31,LSM4,GEMIN7,CD2BP2,SNIP1,SLU7,SNRNP70,GEMIN8,DDX39B,LSM6,SNRPD2,SF3A1,SF3B5,SART3,SF3B4,LSM8,PRPF18,RBM42,DDX23,SNRNP40,SNRPG,USP39,SNRPB2,SNRNP27,PRPF4,LSM2,SF3B6,SNRPA1,RBMX2,PPIH,ZMAT2,SNRPN,LSM10,TXNL4A,TSSC4,SF3B1,MEPCE,SMN1,ARFGEF1,SNRPB,DDX46,SNRPD3,SNRPD1,LSM3,HEXIM1,LSM5,SNRPA |
| 4.744e-06 | -12.26 | regulation of phosphate metabolic process | biological process | GO:0019220 | 1154 | 408 | 18204 | 5365 |
LGALS3,EPO,IL34,IKBKB,CNOT7,APOC2,IL7,IL3,EZH2,CHRNA7,TSPO,RAP2A,IMPACT,CDKN1B,SESN2,MIR711,GPNMB,FAXDC2,PGR,MIR212,PPARG,CCNA2,PAQR3,CCNY,SDCBP,DIPK2A,TAF7,STK4,FKBP8,SPPL3,TP53,ITGA6,KCTD20,IL21,MIR34A,LEPR,IL13,FGFR1,P2RY1,MIR26B,PTPRQ,GHR,ADORA1,FGF22,PTPN1,RAP2C,ZBED3,PTPN11,DLG4,TRIM27,APLNR,TLR4,TNFRSF14,PSMD10,HSP90B1,SPHK2,TMSB4X,ZNF622,CDKN1A,ILK,TAFAZZIN,STRADB,RB1,ADNP,DDR1,YWHAB,LDB1,ACVR1,CLDN3,F2,ACTB,CAMK2N1,DDRGK1,MAP3K11,FGF3,FGF17,ADIPOQ,TNF,RAF1,CX3CL1,ROCK2,CDKN2C,AVPR1B,TRAF2,CX3CR1,TRIM6,RPS3,PPP1R1B,PHB1,FGF7,CORO1C,DNAJC10,EPHA2,RGS2,HEXIM2,BCCIP,FBP1,CAB39,PYCARD,HRAS,AGER,PKIA,DUSP10,IFNB1,CAV1,SOCS3,TAB1,MAVS,SMG5,FKBP1B,SWAP70,CDKN2D,AGAP2,HSP90AB1,MEF2C,CAV3,EFNA5,PKIG,SOCS5,CNKSR3,NPTN,IL4,IGFBP3,ARPP19,HBEGF,CD4,LILRB4,MIR146A,PSEN1,PPP1R2,MIR106B,DNAJC19,DNAJC30,CCL5,TLR3,EPHA4,FERMT2,FLCN,SFRP1,IGF1R,RTRAF,IER3,PPIA,DUSP19,HSPB1,NUPR1,PRDX3,PSRC1,MIF,IL12A,INPP5K,BCL10,MIR132,HTR2A,TPD52L1,IL6ST,CSF2,SOCS4,CHRM5,HSP90AA1,MAP3K12,CTDSP2,CDK5R1,PARD6A,IL5,MMD,FKBP1A,TLR7,RIT2,MACROH2A1,HGS,MAP2K1,FCGR1A,IDH1,DIRAS3,TADA3,MIR20A,RGN,CBL,STAT2,SOX9,FIS1,DLG3,IGBP1,DBNDD1,KRAS,MAP2K3,DUSP3,CHP1,TGFB2,OSBP,FGF10,SPRED2,TF,NCK1,RAP2B,PTPN22,DKK1,BTBD10,CCR7,DDIT4,TNFSF18,C9orf72,PROX1,ADTRP,ADRB2,GREM1,IL15,MIR137,FGF23,IL23A,SEMA7A,VEGFA,NF2,CEP85,UBASH3B,OSM,TLR8,NTRK3,MIR218-1,CAPN2,NTRK2,CCNB1,NBN,CAMK1,DYNLL1,PIK3CA,NTF4,IFNG,TAB2,TCIM,ROCK1,PDCD4,CACUL1,CAMP,MIR15A,PTGES3,MTMR2,CSH1,RB1CC1,IL18,SRC,ANGPT1,PHB2,HEXIM1,THY1,PIK3CG,LEP,SQSTM1,NHERF1,MAP2K6,CHI3L1,HCLS1,DUSP6,JMJD8,ARL2BP,TESK1,PIH1D1,DRD1,CCNH,GSKIP,TRAF6,GADD45A,CAMK2N2,CCNF,RARRES2,DIRAS1,CCL19,XRCC5,TBK1,TRIB1,MIR24-1,DUSP22,WEE2,RAP1A,SERTAD1,LACRT,DUSP1,YES1,TFRC,SYK,FGF16,RALB,CD40,FBXW7,NKX3-1,HDAC6,PRR5L,STK11,STK38,STAP1,MAD2L2,SMYD3,PAX6,CLEC6A,DSTYK,UCN,CD36,CD80,ZNF592,PRKAG1,MOB3C,IFNK,TLR9,HDAC3,EMP2,PPP2R5A,SMG8,CREBL2,RGCC,SFN,LCP2,CDKN3,EHD4,TNIK,INHA,MIR30B,IFNA2,MIR21,DNAJC3,YWHAG,UBE2K,FGR,LDB2,IL12B,BAX,ERP29,TOM1L1,MOB3B,IL6,IFNA10,GNAQ,CD86,MMP9,PPP1R12A,PPP1R17,ENO1,LDLR,ERRFI1,ROPN1B,PRNP,SPRY1,HAX1,EEF1A1,CLIP3,FLOT1,PPARA,VEGFC,TSG101,JAK2,PTEN,PKIB,FGF1,GNB3,LRP6,NRP1,LACC1,DVL2,CDK5RAP3,PPP1R8,GSK3A,PRKCE,BAD,DEFB114,LMO4,MET,ODAM,FAS,PID1,KIT,CCND1,CDK12,CTDSP1,TGFBR2,IL2,TRIM63,PAK2,MIR221,ATP5IF1,AR,CARTPT,SOD1,DIRAS2,SLC8A1,CRKL,EP300,IGF1,SPRED1,PDCD10,PIK3R3,MIR675,SLC1A1,GH1,HYAL2,GSTP1,BAK1,TXN,CCNI,MT3,CCND3,TNFSF15,NOP53,AKT1,IL1B,IFNA13,SLCO3A1,TLR6,GRB10 |
| 4.745e-06 | -12.26 | LETM1 (leucine zipper and EF-hand containing transmembrane protein 1) | protein interactions | 3954 | 218 | 92 | 19454 | 5460 |
RTN4,GFM1,RPA3,CRYZ,SLC25A51,CDK7,SNRNP27,MND1,TIMMDC1,MTRES1,RPA2,PTPMT1,OPTN,VIRMA,TUFM,CABCOCO1,DNAJC19,MLC1,SFXN1,FASTKD5,METTL15,MAP1LC3B,APOO,AURKAIP1,CENPM,MRPL11,PREB,SNAP29,TBK1,GFM2,SLC25A20,COX4I1,SYNCRIP,SSBP1,AIFM1,PRNP,ARF6,RPL35A,CALR,GRSF1,CHCHD1,TMEM70,DNAL4,PSMA3,HADHA,EP300,AKAP1,EXD2,NGRN,FTL,PHB2,RER1,HSCB,TIMM29,FAM234A,CCDC90B,CYB5R3,MTG1,TACO1,PARL,RABIF,TMEM183A,PMPCA,AUH,MTG2,HTRA2,RCL1,DNAJB6,OSGEP,CYP1A1,COX8A,MRPS11,HINT2,NDUFA4,HSPD1,IMMP2L,KRAS,CYB5R1,CARTPT,B3GNT2,PDHA1,TUBB4B,GATD3,RMND1,COX14,WIF1,ATG7,MTRF1,HSPB1,MRPS26,PEX3,RHOG |
| 4.760e-06 | -12.26 | IL8 | pfam domains | PF00048 | 45 | 28 | 17795 | 5224 |
CXCL14,XCL1,CXCL10,CCL18,CCL4L1,CCL23,CCL28,CCL21,CXCL12,CCL2,CCL27,CX3CL1,CCL24,CCL20,CCL25,CXCL3,CCL3,CXCL8,CCL17,CCL8,CCL19,CCL1,CCL11,CXCL11,CXCL1,CXCL9,CCL5,CXCL13 |
| 4.784e-06 | -12.25 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 2652 | 879 | 18204 | 5365 |
ROCK1,SUPT4H1,ETV6,IL17F,TAF10,APEX1,CD58,PDE4B,TFEB,MIR140,PIK3CG,CD40LG,IL18,ELK3,WRAP53,UQCC2,IL23A,MTA2,SLC38A2,VEGFA,CCAR1,TLR1,IL15,MIR769,MTPN,FGF23,EIF3E,BCL9,SOX14,TCP1,ELK4,DEK,NIBAN2,CAPN2,FZD4,CAMK1,TRUB1,PIK3R1,NR2E1,SETD4,KLF1,PIK3R2,CCL1,OSM,TRIM32,UBE2L3,TRMT112,MED9,LAMP3,PRKAB1,MED23,SERTAD1,BIRC2,YES1,STAR,NIF3L1,CD2,SPTBN1,VSIR,MIR101-1,TCEA1,PRDX6,FOXA3,NME2,NOG,TESC,EAF2,SGF29,CREB3,STK11,ALKBH4,APOBEC3C,MED22,TRIM5,SYK,FGF16,PITHD1,HILPDA,NR1I3,NLRP1,ACVR1B,MED10,BOLL,CD40,SERTAD3,MIR16-1,RDH10,PIH1D1,MAP2K6,IGF2BP1,CCL2,CLEC9A,CHCHD2,PSMC5,ARL2BP,MAPKAPK5,NUP62,POU1F1,WBP2,PDE2A,VAMP3,RNF10,AKAP8L,PIAS1,CYRIB,TBK1,XRCC5,VIP,STAT5A,MRPL12,APOBEC3A,MIR183,TLR2,ZNF287,CYP1B1,TP53INP1,TRAF3IP2,IL6,EFCAB7,ID4,AGPAT1,CD86,PAIP1,PADI2,SOX21,ZNF513,MIR223,ELF1,MMP14,FCER1G,DDX1,HAX1,SF3B4,E2F4,TENT4A,SMARCE1,AKT2,ACTL6A,PPP1R12A,UHMK1,CD274,FOXP3,UCN,GABPB1,CD80,MED27,TP53INP2,GTF2A1,PRKAG1,MAD2L2,SMYD3,SSBP3,RIGI,PAX6,CLEC6A,WNT10B,MIR96,ZNF507,MEF2B,CDC73,DNAJC3,PLCB1,TLR9,SMARCD3,ADM2,HDAC3,MLLT6,ZBTB16,ZNF24,RBBP4,VDR,MAX,TEF,MT3,CREB3L4,NEUROD6,TOX,HMX2,NFKBIA,IGF1,DKC1,ENY2,MIR675,TCF23,CALR,SIRT7,RPS4X,AGR2,TLR6,FUBP3,RPL26,CCT7,ITGA2,SERTAD2,CEBPE,SLC45A3,MIR182,ELAVL4,VSTM2A,PPP3CA,WNT7A,AKT1,DYRK1B,TGFB3,IL1B,CDK5RAP3,RGMA,ATF1,E4F1,TAF11,NR1H2,MIR125A,FGF1,MIR130A,CYTL1,IL2,SOD1,HNRNPAB,AR,XBP1,MET,KIT,PID1,SOST,SOD2,NEK7,NCBP2,ACTL6B,MDM2,TP53,KLF4,ZBED3,PAX9,JADE1,ARF4,TLR4,ZNF473,TRIP4,ZNF574,BAG2,CSRNP3,RAP2C,HSPA8,B2M,LHX2,PRIM2,GTF2I,HEXB,DROSHA,LUM,ZNF668,C1QTNF1,KPNA2,HMCES,APOC2,TRIM44,TRIM15,RBM3,MIR212,EPCAM,PLGRKT,TRA2A,TRIM52,FOXJ3,RHOG,AVPR1B,FCGR2A,RUVBL1,MID1IP1,PHB1,ING1,FGF3,HMGA1,ACTB,TNF,CX3CL1,NGRN,XCL1,RBPJ,SF3B1,MED11,EMILIN1,HINFP,ITGB8,CCT8,LURAP1,GTF2A2,MZB1,IL1RAP,TOP2B,FGF7,SH3BGRL,PLAC8,HFE,ILK,RB1,CITED1,NLRP2,NFYA,TENT5C,SUPT5H,MED4,CDK9,NDN,CLDN3,AIF1,IRF4,FOXC2,NEUROG2,GJA1,ZBED4,MIR17,NLRP3,CEBPG,CNTN1,RTRAF,SFRP1,IGF1R,AGO1,NUPR1,RORB,CCL5,TLR3,AKAP12,DYRK2,MOSPD1,DEFB124,PELP1,CSF2,RFX4,IL6ST,GTF2F2,BARX2,HEY2,IRF3,MAP3K12,SETD7,KLF12,YWHAH,MIF,HNF1B,CCL3,BCL10,MIR132,IL12A,EIF5A2,LILRB1,TADA1,ING2,RUVBL2,GPBP1L1,TYROBP,ZBTB17,MAVS,KANSL3,CD46,MIR149,FAM98A,NLRP9,ARPP19,MIR146A,CD81,NKRF,DGCR8,MDC1,HSPA5,IL20RB,MYD88,ILF2,IL4,TAF5L,LTB,RERE,TLE1,RPRD1B,SCAND1,TRIM8,PARM1,MAP2K3,LRP3,UAP1,STAT6,ISG15,CCR7,MBD3,PRDM4,HAND2,ZNF345,ADRB2,HCFC2,RFC2,MSL2,DHX9,DKK1,HOXB1,SPP1,MAP2K1,HDAC5,MIR511,HGS,IRF8,PRMT2,NUCKS1,ANKRD49,EDF1,IL5,RGMB,ZBED1,TLR7,CDC5L,KDM1A,NR1I2,PRPF19,TOPORS,DNAJB9,CNOT6,SF3B5,RBM23,PAEP,HOXC4,RGN,SUB1,HNRNPA0,SOX9,STAT2,STK16,MEF2A,MED17,IFNG,ZNF175,PHB2,CD200,TRIM21,ATF4,POLR2G,LEP,HNRNPK,SQSTM1,PTGES3,NRDE2,SRC,SMARCA5,ANGPT1,ZNF609,BMPR2,TFE3,SEMA7A,MIR29A,EXOSC3,MPV17L2,SMAD9,TICAM1,NFE2L2,SOX3,BMPR1A,SMARCB1,MECP2,ZNF319,NTRK3,TLR8,IFI16,NTRK2,STARD4,CCT5,LMO3,RFXANK,ACTR2,METTL14,EIF2B5,PQBP1,IRF1,AFAP1L2,UTP15,HNRNPD,WNT2,TAF9,TUSC2,KMT5B,EIF4A3,TRIM62,TFRC,SELENOK,PCBD1,SMAD3,CRTC2,CSRNP1,NKX3-1,ATF3,PKNOX1,RPS7,FCGR2B,STAP1,CLU,MIR205,KLF10,MED30,NFKB1,TERT,PABPC1,SUPT3H,PLP1,HLF,BMPR1B,TFCP2,IRF2BPL,FOS,HCLS1,CHI3L1,CCL19,TLR5,PLAGL1,RNF40,CD38,NEK2,TRAF6,FXR2,NDP,TICAM2,ERP29,GTF2F1,RFX5,RSAD2,MIR107,ZNF267,ZFP64,FOXP1,THRAP3,STOML2,DUOXA2,FGR,RNASEL,POLR3B,LDB2,UBE3A,IL12B,RNF14,MTA3,ZNF263,NEUROD2,PPARA,PELI1,IFNGR1,RXRG,FLOT1,CXXC1,OTX2,JUNB,PRL,PNP,JUN,HAS3,LDLR,ENO1,HSPD1,DMAP1,POLR3F,RBBP9,CD36,MIR33B,RMND1,FOXD3,POU5F1,TCF21,IREB2,LYAR,ELK1,MED29,LILRA2,MIR21,MIR30B,ECD,DNM2,MIR548C,SYNCRIP,MYBL2,RGCC,CREBL2,CTNNB1,HYAL2,SHLD1,BACH1,KLK5,GPT,TMEM106A,EP300,SNX5,PDCD10,RFC3,NAA16,PIK3R3,EIF3D,WDR77,KARS1,PRMT5,TANK,SMAD4,INO80E,LMNA,UBE2V1,RAMP3,DVL2,KPNA6,LACC1,CRY1,GSK3A,RAB27A,CD34,MED31,MORF4L1,JAK2,LMO2,CAND1,STAT1,PKIB,TIRAP,LRP6,CDK12,SS18,PSMC3,RRN3,TRIM24,MSN,CREBZF,TNFSF13,AATF,ODAM,GRIA1,LMO4,EIF2AK2,CD14,MLLT11,MIR206,RLN2,MITF,VPS72,ITGA6,IL21,CLEC7A,UBP1,MIR34A,IL13,TAF7,CXCL8,IDO1,TENT5D,TOMM70,PTPN11,TFPT,CDK6,DNAJC2,DDIT3,TRIM27,SRSF1,P2RY1,HELT,FGF22,SIX5,ACSS2,SCAMP5,VGLL2,YTHDF2,ESR2,NCSTN,NFYB,IL7,ITK,EZH1,RFXAP,UPF3B,IER2,NR4A2,RAD21,EPO,SLC6A4,EGR1,GAPDH,IKBKB,IL34,MYRF,TGFB1I1,CNOT7,SP1,PPARG,CCNA2,PTGER4,RPL23,SFRP4,RNF20,PRKCQ,JUP,MIR106A,RNF187,ZNHIT1,PGR,NMBR,RFC5,MSX1,TRAF2,MIR145,LY96,TRIM6,EEF2,RPS3,DDRGK1,POLDIP3,ADIPOQ,CRLF3,RBBP7,FGF17,NAA15,LBH,RAF1,ARMCX3,IL10,ROCK2,MIR640,YAF2,H2AZ1,PTGFR,LARP4B,S100A10,GABPA,AGER,HRAS,MIR23A,PYCARD,ZNF304,BATF,YTHDF1,HMGB1,ZNF770,INO80C,SSBP4,TRA2B,FBXW11,CGAS,OGG1,CXCL10,TNFRSF14,ZNF593,SPHK2,RFC4,USP16,POMT2,CCR2,PLSCR1,MIR657,BRD3,TFDP2,ACVR1,LDB1,MYC,CREB1,FRMD8,HSPB1,MARS1,CASK,G3BP1,GPSM3,SPON1,HNRNPA1,SSBP2,DLX1,WWP2,SMAD5,MED21,HSP90AA1,NFIL3,TNFSF8,SASH3,PDCD5,CD83,PSRC1,INPP5K,DDT,HTR2A,CDK1,ATP6AP2,APLN,RPS6KA4,OSR2,PIM2,CBFB,HSP90AB1,RAB1A,CD28,MEF2C,SUPT7L,MSTN,MEPCE,IFNB1,CAV1,TNKS,MEAF6,ZGLP1,APOBEC3F,MIR324,SNRNP70,CD4,PSEN1,TNKS2,EGR2,RPS27L,RBM22,IFIH1,ZMPSTE24,RUNX1,IRF9,TAF2,SMAD2,BRCA1,SLC38A3,BUD31,FGF10,PCNA,ZBTB38,TF,IL2RG,IRF6,NCK1,SRPK2,SVIP,KRAS,NOTCH2,RASL11A,ACTA2,DPY30,IL1A,CHP1,TGFB2,MIR144,KLK3,PIWIL2,CDH13,ADTRP,MTDH,CREBBP,PROX1,ZBTB18,GREM1,TRIM37,IRF2,PTPN22,SOX2,WASL,NFKBIB,ABHD14B,PXYLP1,DYRK1A,FOSL2,LTA,PAGR1,PRKCB,CTBP1,SHC1,COPS5,HNRNPC,TRAF3IP3,SETD3,OAS1,CCT2,SMAD1,IRF7,ACTN4,MACROH2A1,RIT2,PYM1,LITAF,PICALM,MAFG,CDK7,TRIM22,CCL21,CIRBP,NFE2,TADA3,MTF1,AIP,BAZ1B |
| 4.828e-06 | -12.24 | AUH (AU RNA binding methylglutaconyl-CoA hydratase) | protein interactions | 549 | 303 | 121 | 19454 | 5460 |
MRPS34,QRSL1,COX6C,HSP90B1,MRPL10,NDUFAB1,NTPCR,GRPEL1,MRPL20,POLDIP2,NME4,PDHB,MRPL17,MRPL41,MRPL40,TWNK,DLAT,GFM1,OAT,ALKBH5,MRPS16,NDUFAF2,PYCR2,MRPS28,ACAT1,MRPL53,MRPL49,MRPL51,NDUFS3,DDX39A,PPIF,HADH,METTL15,BCS1L,ATP5PB,MRPL47,NDUFA2,MRPS18C,MRPL22,FASTKD5,PDE12,MRPS33,HSPE1,MRPS18B,HSD17B10,THG1L,ATP5PF,TRMT5,GRSF1,ATP5MG,COX5A,ATP5PD,DBT,MRPS23,MRPL24,MRPL50,MRPS9,SDHB,COX4I1,MGME1,ALYREF,NDUFA5,VAV2,MRPS18A,ATP5PO,IDH3B,PRDX3,NDUFAF3,MRPL12,MRPS7,NDUFS2,OXCT1,HADHA,NGRN,FAM107A,NSA2,MRPS25,NOA1,MRPL16,AUH,MTG2,HNRNPAB,PYCR1,NDUFAF4,ATP5F1B,MRPL23,MRPL13,TACO1,DLST,NDUFA12,NUDT19,NDUFS6,PDHA1,RAF1,HSDL2,ETFB,MRPS17,COX7B,HNRNPDL,SSRP1,RAD21,KGD4,ETFA,ATP5F1D,HINT2,MRPS11,HSPD1,PREPL,THNSL1,MRPS26,MRPL18,NDUFV2,MRPL9,MMUT,CTNNB1,CLPX,DDX50,STOML2,MRPS35,NDUFS8,HNRNPL |
| 4.843e-06 | -12.24 | response to stimulus | biological process | GO:0050896 | 7803 | 2435 | 18204 | 5365 |
RPL23,SFRP4,RAB39B,PTGER4,CCNA2,CSNK1A1,RACGAP1,SP1,LIPA,NSDHL,JAML,CYP7A1,OR1S1,RHOJ,GPNMB,JUP,SELENOW,STK24,PDE9A,BTG2,TSPO,RAP2A,CHRNB2,IER2,IL7,OR10G2,AK3,RAB32,ITK,FBXO22,PYCR1,ESR2,TPRA1,FZD6,EDEM3,CNOT7,MYRF,TGFB1I1,PLPPR1,GAPDH,SLC17A5,TPBG,SLC6A4,CNTN2,RAD21,LRRC8A,FKBP10,TRIM27,FAM13B,SLC4A10,SEC11A,AZGP1,TFPT,CDK6,NONO,PTPN11,HUWE1,CCL11,OPA3,MICB,SELENOP,NETO1,FAM3C,SCAMP5,SGIP1,VASH1,FGFR1,TMEM87A,H2BC12,IL13,PNOC,MIR34A,FHIT,VPS4A,APEX2,IL21,CLEC7A,MITF,SPPL3,HADHA,MADCAM1,CD1E,IDO1,BLOC1S2,TAF7,FBXO3,RHOH,UFM1,HSPB8,PSMD14,RASGEF1C,INA,SLC29A1,LDB1,STK38L,AIPL1,RPS16,XAF1,SLC22A8,DDR1,SCN2B,RAB9B,CFTR,OR5AN1,OGG1,TRIM23,ANKH,RAG1,FBXW11,ADO,SPINDOC,H2AX,NKIRAS2,ZNF622,CIDEB,GPR176,SPHK2,CXCL10,TNFRSF14,ICOS,TAPT1,MAPK10,OR10A6,ERAS,RHOB,BATF,MIR23A,ZNF304,AGER,OR5M9,CAB39,EPHA2,INO80C,RDH11,OR2A25,MME,RASSF8,CORO1C,TRIM6,MS4A7,CINP,RPS3,CNTNAP1,TRAF2,FBXO31,MRGPRX2,CBX5,NMBR,HRH3,OR2J3,ROCK2,H2AZ1,MLN,FGF17,PLAAT3,ADIPOQ,CCR3,RPS27L,LILRB4,EGR2,ARL6IP5,TRIM26,HBEGF,INSYN2A,PLPP6,S100A11,POLR2I,ABHD12,MIR421,IFT57,WWP1,SNX3,TAF2,GFI1,ZMPSTE24,SLPI,IFIH1,ARHGAP19,CAV3,MSTN,MEF2C,MSRB1,CD28,TAX1BP1,HSP90AB1,ERLIN1,FKBP1B,RC3H2,USP8,GPBAR1,HTR1A,DCTPP1,TRIM11,ATP6V1A,ACHE,FGF12,CYP2F1,WDR45,CDK5R1,TGIF2,HSP90AA1,USP15,NDUFA12,SMAD5,SOCS4,SAP30BP,KLF9,MOV10,PELI3,APLN,INPP5K,HTR2A,CD83,ZFAND6,APOBEC3G,PRDX3,PTGES,GPR17,IFNAR1,SLU7,HSPB2,TUBA1B,CREB1,TXNDC17,IER3,SELENOF,DOK6,HNRNPA1,PRICKLE2,ZNF207,G3BP1,FMO2,CDK7,ATP1B1,IFI35,TAAR6,BAZ1B,MTARC2,OR51M1,TNR,CTNNA1,FZD3,PRCP,CIRBP,TADA3,NFE2,MIR20A,HBP1,CCL21,GPX4,TRAF3IP3,RAP1B,CHGA,SHC1,PRKCB,SLC25A24,PAGR1,MCHR1,TMEM170B,TMEM255A,MACROH2A1,RIT2,MAD2L1,CRYGD,LCN8,USP14,EDEM1,NABP1,HPS6,NCKAP1,ATP2B4,GREM1,TOM1L2,FUNDC1,ADTRP,ENHO,MTDH,FOLR2,CDH13,VPS4B,AP5S1,HSBP1,C1QC,TTC4,PEX13,FMO1,NFKBIB,PDE8A,SOX2,PTPN22,IRF2,RAP2B,CPT1B,ZBTB38,PCNA,DEFB116,ATP5F1B,GKAP1,NAT2,METAP1,PAK6,FCN2,CLPB,TGFB2,CHP1,KLHL12,POLB,SLC6A3,ACTA2,PLSCR3,CRIP1,SRPK2,NOTCH2,ACTR2,NBN,FBXO44,BLOC1S5,SHOC2,BPIFB1,CTNNBIP1,CCT5,TFIP11,GSTK1,NTRK2,IFI16,FLRT2,PGK1,MKLN1,MAN1A2,AFAP1L2,RND3,C1GALT1C1,IRF1,PQBP1,MOG,SLC41A1,EXOSC3,BNIP3L,ADGRG1,BMPR2,MECP2,NDC80,SIGMAR1,MIRLET7I,TAS2R39,GNG13,MIR181C,SNX17,AKR1C1,TICAM1,SMAD9,HNRNPK,ATF4,CD1A,TRIM21,ZMAT3,FIBIN,PLCB2,OR2A2,HEXIM1,TFPI,PSEN2,ANGPT1,PPID,SRC,ADRA1A,MSRB3,NRDE2,SRGN,PNMA1,EXT1,PTGES3,TOM1,LGR4,TACR3,MEF2A,PRKRA,HBA1,PDCL,ARMT1,RNF121,IFNG,TAB2,FAU,GPR37,NUDT4,DTL,MEIOB,MACROD1,TMEM117,ADGRE2,PDYN,ACAT1,TRIB1,CCL19,MT2A,PACRG,LRTM2,NAE1,TICAM2,HP1BP3,TRAF6,OR52W1,THBD,GSTM4,CCL4L1,PLP1,MRAS,KCNJ8,WBP1L,NFKB1,B3GNT2,ARG2,RNASET2,MT1M,SOSTDC1,RPAP2,CYP2C9,PSPC1,CHI3L1,FOS,KLRF1,TAFA1,FBXW4,STAP1,DNAJC4,FCGR2B,ATF3,AKR1B1,KLF10,WDR83,RALB,SELENOK,OR5V1,TMIGD3,TRIM62,PLSCR4,EIF4A3,KMT5B,TMEM108,TAF9,CRHBP,COL1A2,KLRC2,RHBDD3,CCN3,WNT2,HNRNPD,CD63,DUSP22,CSRNP1,SMAD3,SLC7A11,ATG16L1,IFIT2,PLP2,HADH,VWF,ECRG4,INHA,MIR30B,CD9,MSX2,GPX5,LILRA2,AQP4,RGCC,LST1,OLFM3,EXOC1,MYBL2,LEAP2,ILDR1,RWDD1,RGS10,ABCC2,POU5F1,OR8I2,OR51S1,RMI2,RERG,SELL,POLR3F,MIR210,RRAGB,VAV2,CFC1,APTX,AQP2,BCL2A1,OR6X1,SIN3A,LYAR,ELK1,CHMP2A,GPR37L1,SLC1A3,EMX2,UPRT,FLOT1,OR10G3,SULT1B1,GPX2,IMPA2,PRELP,WSB1,MT1X,CBX3,VDAC1,ROPN1B,CNNM4,TAS2R13,CPLX3,HSPD1,PPP1R17,CHCHD6,MORC2,PNP,JUN,LRRC69,CAMLG,RTKN,MIR107,BGLAP,RSAD2,SERPINA1,USP2,IL12B,RNF14,UBE3A,UBE2E2,POLR3B,RNASE6,MIR185,STOML2,PEA15,GPR26,FOXP1,MYO6,CXCL9,CRKL,MSN,TRIM24,DIRAS2,PLAA,GNG11,OR10P1,OR4D5,GPR160,MLLT11,NRBF2,ODAM,AATF,TMEM126B,ADRB3,DEDD,DERL1,BAD,GRID1,G0S2,MIR545,GSK3A,OR1F1,ADCY2,AKR1A1,RAMP3,TIRAP,NPW,NCALD,BST2,LIMS2,P2RY10,STXBP1,CDKL2,BCL2L1,SELENOS,GRB10,TANK,ISG20,AMELX,UBXN6,DRD3,MT1E,DDI1,GABARAP,STARD13,MIOS,TBC1D4,AKAP17A,PDE6D,RNASEH2C,UBE2V2,CDC7,FAM53B,OR4B1,ZMYND11,LMNA,GPX1,TMEM106A,IFT25,CCL24,CTSK,BACH1,SLC1A2,NPR2,INMT,OR4D6,BOK,NPC1L1,PIK3R3,RFC3,AP1M1,VDAC2,EP300,RNF103,CD247,DAAM1,CAP2,TP53TG5,LYG2,SLC15A2,SCFD1,CHMP4C,UFL1,CXCL13,HOMER3,SLC25A12,ASB7,TRIM52,CDKN1B,MLC1,S100A6,DROSHA,SLC22A6,CYP2C18,FAF1,MIR195,TRIM15,SDHAF4,GPM6A,CYP27B1,LGALS3,CER1,DLG4,CYB5B,IFI6,ALKBH3,PAX9,CLCA1,HSPA8,PPIB,LILRA3,TAS2R5,PTPN1,TIMP4,TRAM1,RAB30,TMEM33,ACKR3,POR,OR10A7,DDX5,MIR1-1,GNGT2,HPCA,NRGN,TP53,FKBPL,RCVRN,OR8B8,HTR5A,PSMB5,LYZL4,FADS2,TAC1,MDM2,MPG,UBIAD1,SDCBP,TENM3,CSNK2B,PDCD1LG2,GGCX,FUT8,TAS2R16,IRF4,NHEJ1,ABCF1,ARF6,CLDN3,KCTD9,CASTOR2,CCL25,NLRP3,MIR214,RGL1,YWHAB,PPM1D,NPY5R,NLRP2,NUP35,GNG7,TNFAIP1,SLC22A12,ILK,TMEM107,RNF152,CCL18,CASP4,EID2,LCN1,CDKN1A,MIR105-1,MPST,LRAT,TOP1,LSM14A,DUSP10,CHRDL1,GPR15,RNF5,OR8G5,PCLAF,MIR98,KDM2A,CDK5,KCNMA1,CLDN4,PLAC8,CXCL12,CYP4F12,CYP3A5,STUB1,DNAJC10,FGF7,PHB1,ERLEC1,RPA2,RDH12,ANP32A,FCGR2A,TEX12,MUL1,GRM8,PPT1,GINS4,MIR1298,CX3CL1,EXD2,VAPB,DGCR8,MIR146A,TXNRD2,PDP2,CCDC186,FXN,IL4,GTF2H4,OR5I1,TACR1,PSMB10,MDC1,DKK3,RUVBL2,GSTA2,ING2,EFNA5,GPR35,CMA1,RNF7,SWAP70,CSNK1G3,CCL27,F9,CHID1,CFL1,STK3,OPRM1,RNF34,SETD7,AKAP1,MAP3K12,IRF3,HEY2,PDE7A,ELMOD2,SOD3,SHPRH,IL12A,REN,BCL10,HNF1B,MIF,RAB9A,NDUFS8,DUSP19,SOCS2,CRYAB,NUPR1,FZR1,FLCN,GGCT,PPP2R5E,SLC6A2,CCL17,UBAC2,DYRK2,AKAP12,TRIM68,TLR3,KCNB1,RGS19,CCL5,CST3,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RD1,KCNJ10,SARM1,LMBR1L,CDH8,ALKAL1,NR2F6,STC1,EEF1G,CXCL3,FGFBP1,MIR21,CPNE1,GUK1,CREBL2,PROS1,UBE2B,JAK1,HACD3,SYNCRIP,GNAZ,NPB,SMURF1,GNRHR2,EMP2,DNM2,MOB3C,SLCO1A2,PCK2,KCNH1,LDOC1,ARPC3,GJA10,LIG3,CD36,TPT1,RBBP9,PMAIP1,BAP1,NEURL2,OR4Q3,MLH3,SERPINB9,IFI27,TSPAN18,ADCY3,GPC4,PAK5,RPL39,VEGFC,TRAF7,RXRG,IFNGR1,ST13,PPARA,PELI1,ADRB1,NEUROD2,EEF1A1,PPP4C,GRM1,LANCL1,GRIK1,DMAP1,TRPC1,LDLR,ENO1,TRIM34,TOP3B,PRL,CD79B,JUNB,CSK,GTF2F1,SLITRK5,PI3,STAMBP,SPG21,MX2,FGR,RNASEL,PDE6A,BRAP,ALCAM,NPBWR1,YWHAG,TXNRD3,CYP2C8,TMEM229B,NCOA5,RRN3,SLC8A1,CARTPT,UBE2N,STK26,ATP5IF1,MIR221,SS18,RLN2,SEC61B,GNAI2,IL22,POLL,EIF2AK2,CD14,GRIA1,CDC42EP2,CREBZF,HPF1,TNFSF13,ACACA,TUBA1A,RAB27A,CD34,SMCHD1,UGCG,DEFB114,CRY1,ASF1A,L1CAM,LACC1,HBM,DVL2,LRP6,IRAK1BP1,STAT1,VLDLR,USP3,LYZL6,JAK2,PTEN,MORF4L1,INO80E,SMAD4,ARHGAP15,SEMA3C,ASB3,GPR146,MAPK4,PDIA2,NDNF,TNFSF15,NOP53,PYCR2,SERPIND1,BRS3,UBE2G2,P2RY4,UBE2V1,RALA,GPT,SHLD1,HYAL2,MIR95,SLC1A1,SP2,CTNNB1,CYP2R1,KARS1,CD164,PRKD3,PDCD10,CERS6,F10,AOX1,EPCAM,APOBEC3H,SGTA,RPL15,PAPSS2,MIR212,SLC16A1,FCMR,RHOG,CHMP5,SUFU,IRAK4,GSTA1,PPP2R1A,TNFAIP8L2,SUV39H1,NREP,CDO1,CD3G,IMPACT,KLHL22,ALG2,NQO1,HELLS,STRBP,PLGRKT,IPO8,ATAT1,EIF2B2,B2M,GABARAPL1,GPHN,TRIM44,SIAH1,GAPT,RBCK1,HINT1,HMCES,ZNF668,MIR638,RNF139,CBR3,LRRC28,MPP1,APLNR,TLR4,SEC14L1,HMOX2,TOR1B,PIP4P1,INPP4A,HOMER1,ZBED3,KLF4,OR5L1,OR4M1,RAP2C,CIAO3,GHR,BRINP2,LARGE1,LAMB2,MIR26B,RAD1,CRABP2,PCGF2,TRIP4,TMEM38B,UGT1A1,MGMT,ARHGAP1,MSMP,ANO3,ITGAV,GABBR1,ASCC1,EHD1,CNP,MCM4,ENDOD1,SOD2,NEK7,LEPR,PPP1R1A,MAP3K3,SOST,SYNJ2BP,TNFAIP6,MAEL,ST6GAL1,GNAI3,STK4,VCPIP1,SDC4,TNFSF10,BRINP1,MAPKAPK3,TIFA,FOXC2,AIF1,SLC25A27,ALDH1A3,CEBPG,CNTN1,OLFML3,MIR17,CKLF,CXCR3,CHST2,GJA1,OR52M1,SLC25A5,GREM2,RB1,CITED1,IK,LRRC8D,CALML5,TBC1D10C,CYP11B1,MRGPRX1,RSRC1,TYMS,RAB31,GPR83,PTGER1,GPHA2,NDN,DRGX,CDK9,TMSB4X,FOLR1,IL1RAP,PLG,FBP1,HINFP,ITGB8,TBC1D24,ARHGAP12,EPHB6,HSH2D,TOPBP1,ELMO1,HFE,RAB11B,BCL6,RHOU,DDAH1,TOP2B,EDA2R,CSRP1,PSMA2,PDE12,RUVBL1,PDIA3,ATP1A1,AVPR1B,SEC13,RBPJ,XCL1,TMUB1,SHMT1,TNF,HMGA1,ACTB,DEFB121,CYP11B2,FGF3,TWSG1,CD81,TCP11L2,NUDT1,TULP3,CRYBB2,NLRP9,IGFBP3,MIR149,EPHX1,AQP3,CD46,TRIM54,MYD88,HSPA5,IL20RB,SOCS5,GPR162,HTRA2,OPHN1,CDKN2AIP,GSTA4,STAMBPL1,PLCXD3,FURIN,MAVS,SHC3,DEPDC1B,OR9I1,TYROBP,CLIC2,EEF1E1,DOK4,THG1L,NCR3LG1,STX8,CDNF,IL6ST,CSF2,BTN2A2,CNTFR,MAP1LC3B,LILRB1,SCG2,CCL3,ATP5F1A,RAB18,ID1,YWHAH,FRZB,FTH1,PLA2G4B,CDC42,PPIA,SFRP1,IGF1R,FBXO32,CSNK1E,IFT172,FERMT2,TIMP3,PTGER2,RCHY1,PELP1,RAB4A,DEFB124,IL2RB,EPHA4,MIR200A,CNPY3,KCNC1,EFNA3,DLG1,CHST11,IGBP1,UBXN10,BANF1,RAB13,DNAJB9,FMOD,HBB,FIS1,BECN1,TOPORS,STAT2,MCHR2,CCR5,OLR1,OR4K13,EXOSC4,CYBC1,IL1R2,OR4N4,TAS2R40,IGFBP4,FCGR1A,GNA14,CCS,HGS,PRMT2,KCNIP2,PPP1CC,HDAC5,MAP2K1,MAP3K14,SKAP2,OS9,GAD2,KDM1A,NXPH3,TLR7,RASGRP2,IL5,RGMB,SLC38A9,OR51E2,OSER1,HCFC2,SULT1A3,BHLHE40,RNF167,SLC31A1,CXCL1,PPY,CST11,ISG15,CCR6,UAP1,BTBD10,SPP1,DHX9,SDF2L1,RPA3,COL3A1,OR14J1,SPINT2,RMI1,MSL2,TRIM8,IL18BP,EIF2B3,KCNMB1,TLE1,LIAS,RAB29,GABRG2,LTB,DEFB1,HRH2,MIR370,PDE1A,MIR493,OR7E24,OR8B4,GORASP2,GARRE1,OSGIN2,RASGRP3,STIM1,ASB8,OPRK1,SLC52A3,IPCEF1,SSRP1,RAPGEF5,SBK2,NR0B1,SETD4,RLN3,CUL3,RAN,TRIM10,PIK3R1,ACAP2,NR2E1,CCDC47,NF2,LYZ,LAMTOR2,RGS6,SLC38A2,RCE1,ARHGEF6,BCL9,SIT1,MIR455,IL15,NDUFB4,HSPB6,OR4A47,ABHD2,TLR1,FASLG,INSIG2,REG1B,SLC6A11,PIK3CG,VAC14,CNIH1,ABCG2,GNB4,TRIM35,WRAP53,TAS1R2,ELK3,NT5C3A,IL18,GTF2H2,CHST1,GNPAT,SNN,MIR143,CAMP,STAU1,OARD1,PDCD4,TNNT2,NDUFS2,WDR12,TIAM1,TCAP,NLE1,IFT52,PAFAH1B1,NPTX1,CDC42EP3,PPIF,STAT5A,VIP,BPGM,FAM161A,CSNK1A1L,FRS3,RNF10,P2RY11,PICK1,PTHLH,HCAR1,FKBP4,CYP1B1,GLRB,MIR183,TLR2,DUSP9,CLEC12B,CTNND1,OR7D4,HBE1,SNAP23,OPRL1,TMEM231,DRD1,PIGA,MIR16-1,CHRM3,CACNB4,ATP5F1D,DCUN1D3,HPGDS,WBP2,NUP62,MAPKAPK5,SYP,H2AC25,IL2RA,NHERF1,CLCN6,NGB,MAP2K6,CCAR2,CREB3,STK11,HDAC6,TAS2R7,SGF29,NME2,RGL2,POLDIP2,FOXA3,CD40,OR4K1,TMBIM6,DERL2,ACVR1B,SAV1,SCG5,NR1I3,CH25H,EGLN3,LACRT,CMTM7,SLC23A2,BIRC2,DUSP1,YES1,ASB1,PRKAB1,NPC2,GLUL,RLIG1,ASIC1,PDCD1,PARP2,RNASE9,OR5K1,LHB,SLC2A1,CD2,DNAJC3,FABP4,CDC73,IFNA2,DNAJB2,SLC39A9,OCRL,SELENON,GRIA2,DHX16,MCL1,FGFR1OP2,PPP2R5A,WFDC5,LECT2,MGST2,ADM2,TNFRSF1B,KCNIP3,PLCB1,PTH2,TLR9,GNL1,CMKLR2,UTS2R,CD80,ANXA4,UCN,LPAR2,GUCD1,EDNRA,NMI,DSTYK,MGME1,CLEC6A,MIR204,ZBTB33,ADSS2,GMDS,MAD2L2,GPR65,DAPK3,OR2AT4,CXCL14,GNG5,SLX1A,CDC42SE1,CARHSP1,MIR130B,BVES,PRNP,OXSR1,MATR3,ERRFI1,TMED1,MPV17,PLXNC1,COPS2,VPS26B,AKT2,ADIPOR2,OR5AP2,GNAQ,LSM5,IFNA10,CD86,PYDC2,ACAA2,MMP9,CHRM4,TOM1L1,LAMP2,IL6,MOB3B,TRAF3IP2,BAX,MIR379,RTP4,GP9,ENPP4,FCER1G,KPNA1,DDX1,ERLIN2,OR51A4,TREML1,ACVR1C,G3BP2,MIR223,DNTT,RAB23,SLC2A8,SUSD6,RND2,KLRD1,TGFBR2,MSH6,PSMG2,PHF1,FLRT3,KIT,SLCO2B1,FAS,TOLLIP,MET,CPE,EIF4A2,UTS2,MIR320A,CYB5R4,SIVA1,MIR448,PAXX,ACER3,EGLN2,TMEM88,SYVN1,CDK5RAP3,NR1H2,PPP5C,PFKFB2,SLAMF9,B9D1,AGR2,TLR6,IFNA13,RTF2,ESD,CLEC1A,IL1B,DYRK1B,OR4N5,KCND2,AKT1,FAM107A,PPP3CA,SLC6A1,ITGB5,MIR182,ELAVL4,RANBP1,KBTBD2,RETN,CCND3,NPVF,CREB3L4,MT3,GSTP1,GID8,AGTRAP,TXN,TNFAIP3,GH1,SKIC8,CALR,NSG1,ABCB1,TTR,MIR675,UCP2,RFTN2,UBE2W,ROMO1,APH1A,IGF1 |
| 4.917e-06 | -12.22 | detoxification | biological process | GO:0098754 | 144 | 68 | 18204 | 5365 |
GPX4,NQO1,GSTO2,HBE1,SESN2,IPCEF1,GSTA1,SELENOW,MGST2,GSTO1,MTARC2,MT2A,SLC15A2,GSTK1,GPX5,HBB,SOD1,TXNRD2,TXNRD3,GSTT1,MT1A,CLIC2,PRDX4,NFE2L2,HBM,SRXN1,MT1M,AKR1A1,HP,GPX3,CCS,ALOX5AP,MGST3,PRDX1,GPX7,PRDX2,GPX6,RDH11,GSTM2,ESD,SOD3,ABCG2,PRDX6,LANCL1,MT1X,GPX2,SELENOT,SELENOS,MT1E,ALB,GSTM3,UBIAD1,ABCB1,HBA1,TP53INP1,CYGB,TXNRD1,SELENOF,GSTP1,RAB29,TXN,TXNDC17,RDH12,MT3,SOD2,GPX1,PTGES,PRDX3 |
| 4.917e-06 | -12.22 | regulation of mitochondrion organization | biological process | GO:0010821 | 144 | 68 | 18204 | 5365 |
MGARP,PDCD5,CLU,GCLC,LMNA,FAM162A,STUB1,AKT1,MARCHF5,VDAC1,SSBP1,TMEM14A,FBXW7,HAX1,HDAC6,HUWE1,GHITM,MTCH2,PYCARD,SQSTM1,RNF41,SLC25A31,EP300,PLSCR3,IGF1,TNFSF10,SIRT7,FKBP8,BOK,TP53,MUL1,SLC25A4,BAX,IER3,BAK1,ACAA2,MMP9,RALA,GPX1,MIEF1,TFRC,USP30,TSPO,HTRA2,MLLT11,PID1,STAT2,FXN,PPARG,FIS1,ATP5IF1,CYRIB,PPIF,SLC35F6,PRMT6,BCL2L1,PSMD10,FBXO7,PRELID1,PDE2A,PMAIP1,GSK3A,BNIP3L,BAD,SLC25A5,PARL,CTTN,ADCK1 |
| 4.926e-06 | -12.22 | ZCCHC3 (zinc finger CCHC-type containing 3) | protein interactions | 85364 | 167 | 74 | 19454 | 5460 |
MYC,CUL3,HNRNPC,ZNF668,RPL26,RC3H2,DCAF4,IGF2BP1,PAIP2,ELAVL2,UBE2H,H1-1,FAU,CFAP298,RPS9,RPS20,RPL35,PRRC2A,ESR2,H1-5,PABPC5,RBMS2,RPA2,GRM2,LARP4B,RPLP0,RPA3,SIRT7,EXD2,NOG,UFL1,NOP53,FBXW7,STAU1,IFI16,MOV10,GRSF1,IFIH1,HSPB8,CPEB1,HNRNPA1,DDRGK1,TRA2A,SNRNP70,RPS2,RB1CC1,HRAS,SWAP70,SRSF1,KRR1,FUBP3,PRR3,PAIP1,CAND1,FZR1,CGAS,PRNP,LYAR,SURF6,H1-3,APOBEC3D,PAIP2B,EZH2,HBP1,ILF2,AP2S1,RPL31,RBM3,LSM14A,PABPC1,SRSF7,NUP42,RPL17,RIGI |
| 4.941e-06 | -12.22 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1418 | 481 | 16828 | 4835 |
SPOP,USP15,LPAR2,OTUD6B,NTRK2,CCND1,FRZB,CASP4,PTGER2,MYC,NKIRAS1,DIRAS1,CD40LG,BMPR1A,HERC3,PDCD10,EPHA4,PPP1CC,DUSP1,NPY1R,CREBBP,ACVR1,RASGRP3,CDK12,BAD,TIRAP,YWHAG,BCL2L1,FBXW7,CRHR1,DEK,CDKN1B,CXCR3,PTGER4,SDHB,AGR2,GRM1,DUSP9,RBCK1,STAMBP,RBPJ,INPPL1,CAPN2,YWHAZ,SRC,PSEN2,RASL10A,IDH1,NCK1,CDC42,PTEN,DUSP10,MAP3K11,PIK3R3,SYK,CCNA2,GNAQ,SPRED1,LPAR6,PMAIP1,ATF3,SMAD2,USP46,TLR10,RHOU,CCR2,USP8,PTK7,S1PR4,RGL2,RAP2B,TNFAIP3,KCNH8,TRAF7,PPP1R3C,SFRP4,CAV1,IL1A,FZD6,MET,HSP90AB1,ETV6,CDK6,NCSTN,P2RY10,SMURF1,UBE2N,CTNNB1,RB1,RALB,SOCS2,HSPB2,STK3,ADRA1A,PEBP1,FGF13,FGF22,TOP1,FZD3,ADRB2,PIK3R2,USP39,SFRP1,WNT2,ZNF668,TLR4,SPRED2,TRIM36,KLHL12,FGF23,BIRC5,FLCN,JAK2,USP38,EWSR1,STAMBPL1,RHEB,BCKDK,AKT3,PRKCE,PIK3R1,TFEB,GRB10,CSNK1E,HECTD1,ELK3,KDM2A,TRIM24,TGFB3,RPS6KA4,TLR2,FGF10,PAK6,HSPB1,APH1A,TNF,MAD2L2,ATF1,WNT7A,FAS,ERCC3,CCR4,TACR1,SCLT1,FGF7,PPP2R5E,EPHA2,NF2,CAV3,PARP2,RBBP8,MRAS,ACVR1B,FGF17,CXCR1,CSNK1A1,FOSL2,STAT2,SAV1,ELK1,TFE3,CDC7,RAP1B,WWP2,RAP1A,UBE2V2,PPP2R3A,IRAK4,SMAD4,IL2,BAK1,IGFBP4,NBN,CBL,ELK4,RNF126,PIK3CG,EIF4E,RHOH,XRCC5,USP5,GNAO1,THRAP3,STK24,NFKBIB,EXOC2,RAC2,LRP6,DVL2,PPP1R1B,PRKCA,BCL9,BMPR2,SOCS3,PARP11,NLRP3,HSP90AA1,UCHL3,RASD1,KRAS,GSK3A,BCL6,PRCC,DKK1,HERC4,HECTD3,PRKAB1,RC3H2,CNTN1,FBXL19,SF3B1,TAB1,APEX2,SUFU,UBE2B,CHIC2,PIK3CA,SMARCB1,CDH11,MNAT1,FURIN,TNFSF10,BCL10,BAX,GH1,ANKIB1,P2RY12,PICALM,CDK4,APEX1,AKT2,NTRK3,GAB1,LASP1,TPD52,TLR5,BRCA1,TRAF2,NDE1,EIF2AK2,SS18,RUNX1,FBXO32,PRKCB,TRIM27,BIRC2,DYRK1A,RGL1,TSHR,IDH2,TACR3,LMO2,PSEN1,DIRAS3,SOS2,YWHAH,GYS1,FGFR1,DIRAS2,SHC1,CDKN1A,OTUD7B,IGF1R,LCP1,CX3CR1,CSNK2B,ADRB1,FEN1,USP2,MAX,RHOB,G2E3,HEY2,TRIM11,PRKACB,ATP6V1D,GPR37,MYEF2,MGMT,MYD88,NPY2R,TRIM37,HECW1,WNT10B,TRAF6,PTPN1,FBXO11,BMPR1B,ERAS,SPRY1,PPARG,CD46,STK11,FGF3,WIF1,FGF1,MAP2K1,STAT6,LAMTOR3,MLF1,STAT5A,COPS5,NUP62,JAK1,USP13,EP300,FGF12,ADRB3,EXOC1,RAB9B,CCND3,PEA15,IRF4,BAP1,FZD4,AR,IL1B,GRM8,RAB2A,MEF2C,CCNF,RIT1,RAB9A,STK38,TCEA1,ZMYM2,CDC73,RAF1,MCHR2,VCPIP1,RAB5C,USP3,EXT1,USP30,JUNB,RNF182,BRAP,TNFRSF1B,TGFBR2,FASLG,STK38L,CSNK2A1,TTL,CCR7,IGF1,NMBR,DDIT3,EIF4B,JOSD1,ZNRF1,RASL12,RAP2C,KIT,PPP2CB,PPP2R1A,TGFB2,STYK1,MAP2K3,MAP2K6,NRP1,ANAPC11,SPHK2,IGFBP3,GRPR,UBE2A,POLB,GHR,WWP1,S100B,SOCS4,JUN,P2RY1,PIAS1,UBE3A,LTBR,CBFB,RASL11A,CCR3,LTA,OGG1,TFPT,RIT2,RAB23,DDR1,PTGER1,SFN,RALA,MEF2A,TLR6,ACVR1C,NKIRAS2,IL1R2,PAX6,STAT1,DICER1,PPP2R5A,FANCG,TLR7,MSN,AVPR1B,POU5F1,FGF16,TIAM1,NFKB1,VAV2,NEK2,MAP3K3,SENP5,GRM2,RAB5A,PRKAG1,TLR3,TLR1,CCR5,ZBTB16,CD79B,TNKS,LAMTOR2,ITK,FOS,PPP2R2C,STK4,NUP153,DKK3,OTUD6A,HRAS,PPP1R11,RAP2A,MSH6,RRAS2,APLNR,TLR9,RERG,SDHC,IKBKB,AKT1,OR51E2,MITF,NFKBIA,BTG1,CREB1,SOCS5,MDM2,USP14,RAN,SENP8,WDR83,CXCR6,CISH,EGFL7,NPY5R,CXCR4,P2RY4,GNRHR2,RND3,TP53,TFG,CNTNAP1,PTGFR,FBXO22,PSMD14,VEGFA,NCKIPSD,YWHAB,CCR1,EDNRA,SOX3,PML,PTPN11,NOTCH2,PSMD7,CDK7,DUSP6,USP16,CD40,SLC6A2,SHOC2,PPP1CB,LIG3,TLR8,PRKCQ |
| 4.944e-06 | -12.22 | ZFYVE16 (zinc finger FYVE-type containing 16) | protein interactions | 9765 | 99 | 49 | 19454 | 5460 |
RHOG,MED4,RAB5C,LAMP2,ATG9A,LAMP3,SPTAN1,CAV1,STX6,EGLN3,RAC2,TSG101,GJA1,RAB4A,TFRC,PSMC3,HGS,TP53,KBTBD4,TOLLIP,TOM1,KRAS,EPHA4,RPS27A,RHOB,MYO6,LAMTOR1,UBE2H,PRSS1,RAB11A,PPP1CC,RHOJ,CCNF,PHF21A,FGFR1,RPA2,UBAP1,BET1,ELP3,PPP1CB,PRDX3,KDM1A,VPS28,RNF11,STX7,RPA3,RHOU,RAB5A,RAB9A |
| 4.944e-06 | -12.22 | ESRRB (estrogen related receptor beta) | protein interactions | 2103 | 99 | 49 | 19454 | 5460 |
RPS16,RPS27L,HSP90AB1,GNB3,HACD3,PPP2CB,PHB1,RPS2,RPL23,DNAJB2,GAPDH,HNRNPF,TMEM33,RPS27A,SLC25A5,HSPD1,NDUFA4,SLC39A7,TFRC,ERRFI1,PPP2R1A,EEF1A1,TIMM21,TUBB,GNB1,ESR2,RPS3,TUBA1B,SEC61A1,UBASH3B,DNAJC10,SP1,ATP1A1,HSP90AA1,DNAJB6,SLC25A1,ATP5F1A,TUFM,PHB2,STAU1,GNB4,HSPA5,HNRNPH2,HSPA8,VAPB,SSR1,SLC25A3,RPS14,KDELR2 |
| 4.955e-06 | -12.22 | Rab18 (RAB18, member RAS oncogene family) | protein interactions | 19330 | 569 | 208 | 19454 | 5460 |
OSBPL8,PDE1A,ESYT1,POR,HM13,TMEM199,EI24,CDCA3,C2CD2,TES,EHBP1,SRPRA,PTPN1,SRP72,PPME1,LBR,MTARC2,CCDC47,SNAP23,NSDHL,RAB1A,GGCX,ARFGAP3,CHORDC1,HMOX2,USP14,BRAP,SEC63,PDCD5,VKORC1L1,FERMT2,SLC25A4,ODR4,TMSB4X,CTTN,VAMP3,CCNF,PDCL,SLC12A2,GOLGA5,STOM,LMNA,HACD2,SLC35E1,EDF1,SEC22B,ARHGAP1,RABL3,TMEM209,CHMP2B,CERS2,YKT6,MAVS,RTN4,MTDH,SPCS2,DVL2,PDAP1,VCPIP1,C2CD2L,CDK5RAP3,WDR11,BABAM1,NUP35,WDR44,TMEM237,SLMAP,SNX2,SNX1,SPTAN1,OCRL,IGBP1,CYB5B,JPT2,GDI2,STIM1,NUP153,MACO1,ARFGAP1,TPD52,RETREG1,SAR1B,EMC8,LASP1,SCD5,SLC39A7,ZYX,NUDT5,VMP1,CCDC25,HSP90AA1,SCFD1,LMNB1,CAPG,JPT1,VEZT,NIBAN2,CHP1,SPCS1,REEP4,RMDN3,FAM91A1,ARCN1,ELOVL1,VAPB,RAB6A,EHD1,TOR1AIP2,PGRMC1,UNC45A,CSRP1,TTC1,BET1L,EXD2,MAP4,USP15,SHC1,DHRS7,SLC38A2,TMPO,LMAN1,DNAJC1,VTI1B,ARL6IP5,CAMLG,SURF4,UBIAD1,TMSB10,RAP1A,PREB,SNAP29,FKBP8,SRPRB,MOB3B,AKAP12,BCAP29,YIF1A,RAB27A,STX18,RAB13,BICD2,EIF3G,CISD1,GORASP2,PTPN11,C9orf72,CHMP5,EIF4H,STX10,SRP54,ZBTB33,LEMD3,UBE2M,SSR1,USE1,CD2AP,SPTBN1,ZC3H15,STK38,RAB29,TMEM263,TEX264,PIGC,UBFD1,NCK1,TBC1D5,DDRGK1,PPFIBP1,PTDSS1,HSP90AB1,VAMP7,STX5,CORO1C,SWAP70,CSTPP1,CRKL,TAPT1,STBD1,SLC35A2,ROCK2,NUP42,CCT8,RINT1,TMEM87A,SLC38A1,ATG3,RBM27,LAMTOR1,SLC30A5,BAG3,ATP6AP2,STAT1,TAGLN2,EFHD2,TMEM115,SEC22A,YIPF5,BET1,GOSR2,LYPLA2,SSR3,RER1,GOSR1,TLCD1,UFL1,AKAP1,JAGN1,PYM1 |
| 4.990e-06 | -12.21 | organelle outer membrane | cellular component | GO:0031968 | 248 | 105 | 19108 | 5553 |
RPS27A,SFXN2,BAX,COX14,TOMM70,RSAD2,PDE2A,PGR,ARMCX1,BECN1,SARM1,AGPAT5,PTRH2,UBB,RAB32,MT3,UBA52,CPTP,EXD2,QTRT2,IFI27,HINT2,TSPO,RAF1,TOMM6,ARMC1,BCL2L1,KRAS,TOMM20,CHCHD6,SLC11A2,APOO,MTX2,MIEF1,MTCH2,PSEN1,BAD,PPP1CC,VAMP1,CISD1,FUNDC2,SYNE4,TOMM7,CYB5A,ARMCX3,DELE1,HAX1,SLC25A46,MGST3,CPT1B,RETSAT,TOMM40L,ATAD1,BCL2A1,VDAC2,MFN1,EPHA4,CYB5R3,CHCHD3,MCL1,FIS1,TOMM22,GPAM,PGRMC1,BOK,ENO1,PMAIP1,CYP27B1,UFL1,THG1L,ACSL4,MGARP,AKAP1,SNN,VDAC1,CYB5B,GK2,SYNJ2BP,TOMM40,SIGMAR1,ARMCX2,AGK,USP30,RMDN3,CNP,SH3GLB1,MARCHF5,STARD7,TAFAZZIN,RAC2,DMPK,TRAF3IP3,PHB2,FATE1,SAMM50,CNR1,MAVS,BNIP3L,MTARC2,MUL1,TUFM,BAK1,ATP5MC3,DCAKD,FUNDC1 |
| 5.014e-06 | -12.20 | glutathione metabolic process | biological process | GO:0006749 | 54 | 32 | 18204 | 5365 |
MMACHC,GSTA1,G6PD,GSTM2,MGST2,GLRX2,GSTO1,NDP,GSTM4,GCLC,GSTO2,SOD1,ARL6IP5,GSTK1,GLO1,HPGDS,GSTT1,GSTT2B,DPEP1,GSTM3,SLC7A11,CHAC2,GGT7,SOD2,IDH1,GPX1,GSTA2,GSTA4,SLC1A1,SLC1A2,GSTP1,GSTM5 |
| 5.017e-06 | -12.20 | protein modification by small protein conjugation or removal | biological process | GO:0070647 | 800 | 293 | 18204 | 5365 |
DCAF4,KLHL7,WWP2,RNF14,UBE3A,CDC16,UBE2E2,UBE2K,TRIM68,BRAP,ANAPC4,USP2,COPS7A,STAMBP,FBXO32,TRAF3IP2,KBTBD13,RCHY1,FBXO11,USP38,SOCS2,UBB,CDC20,FZR1,COPS2,RNF122,TRIM34,HECTD3,MARCHF5,HERC3,PELI3,SHPRH,NEUROD2,USP15,RNF181,MED21,WSB1,SOCS4,UBE2A,TRAF7,KLHL25,PELI1,RNF34,IFI27,TRIM11,SOCS3,URM1,RC3H2,NMI,USP8,TNKS,NEURL2,CBFB,OTUD6B,VPS18,RNF7,BAP1,FBXO25,USP5,STAMBPL1,MED27,UBA3,SOCS5,SMURF1,SPOP,IFIH1,KLHL3,ATG7,COPS4,TRIM54,BRCA1,UBE2B,ZBTB16,WWP1,ANAPC2,UBE2I,KLHL24,EGR2,TNKS2,UBE2S,TRIM26,RNF113A,FEM1C,PPP1R11,KLHL12,UCHL3,RNF39,UBE2W,DCAF11,RNF103,KLHL15,FBXO9,NEDD8,WDR77,RLIM,RING1,RNF11,TNFAIP3,CTNNB1,TRIM8,OTUD7B,COPS7B,RNF208,HERC4,UBE2G2,UBE2V2,MSL2,USP13,UBE2V1,KBTBD2,TRIM37,SIAH2,FEM1B,DCAF16,AKT1,UBA52,RPS27A,RNF8,ISG15,MARCHF3,RNF128,MARCHF9,ASB3,UBE2F,RNF167,USP14,ZBED1,MED31,E4F1,OS9,PRPF19,ANAPC11,OTULINL,CAND1,USP46,SYVN1,CDK5RAP3,CTU1,RNF126,COPS5,SUMO1,TRIM22,CBL,PCMTD1,SPSB1,TRIM63,SKP1,UBE2M,TOPORS,DESI2,WDSUB1,DCAF5,TRIM24,UBE2D1,MARCHF4,UBE2N,SPOPL,RNF146,MDM2,DTL,FBXL3,CDC26,RNF121,MED17,ZC4H2,SUMO3,CDC23,VCPIP1,ZNF451,TRIM45,UBE2D3,ANAPC16,USP30,SENP5,TRIM35,SUMO2,G2E3,ASB11,FBXO30,ANKIB1,HUWE1,CRBN,ENC1,CBLL1,TRIM27,RAB40AL,RNF41,FBXL7,TRIM21,UBE2H,HINT1,FBXO7,NFE2L2,CUL2,RNF139,NSMCE3,DET1,SIAH1,TRIM15,TRIM44,RBCK1,FBXO22,SPSB3,CCAR1,RNF115,TRIM52,COP1,CUL3,UBR7,HECTD1,CDCA3,KLHL22,TRIM10,RNF20,ZNRF1,NQO1,RNF187,TRIM3,ASB7,AREL1,ASB8,UFL1,DESI1,NBN,JOSD1,APPBP2,NT5C2,DDRGK1,DCUN1D5,MUL1,KCTD10,FBXO31,TRAF2,TRAF1,UBE2L3,TRIM32,CDK8,SENP8,TRIM6,BIRC2,KBTBD6,ASB1,ELOC,TRIM62,IRF2BP1,BFAR,FEM1A,STUB1,KCTD11,MED30,STX1A,ANAPC13,OTULIN,MED10,CISH,KLHL9,HECW1,HDAC6,RNF5,RNF182,MED11,FBXW7,TRIM5,DCUN1D1,UBE2E3,IRF2BPL,ATG3,USP16,PML,RAG1,FBXW11,SPATA2,DCUN1D3,RNF152,RNF141,TRIM23,TNFAIP1,RNF144B,NAE1,NDP,KCTD9,TRAF6,CCNF,MYLIP,PIAS1,RNF10,FBXO3,RNF40,RNF133,OTUD6A,UFM1,RNF26,PSMD14 |
| 5.062e-06 | -12.19 | SAFB2 (scaffold attachment factor B2) | protein interactions | 9667 | 184 | 80 | 19454 | 5460 |
APOBEC3D,MAP1LC3B,ZNF263,TOP3B,SUPT5H,TP53,E2F4,TOPORS,FURIN,NUPR1,EZH2,PNMA2,IK,CHMP4C,ZC3H11A,EWSR1,EMC2,MAP1B,CCAR1,PSMD12,DPM2,RIGI,SSRP1,G3BP1,VDAC1,HNRNPA1,COPS5,MOV10,HMGA1,IFI16,RB1CC1,ANKRD50,UQCR11,DDX23,SNRNP70,EED,MAP1LC3A,ZBTB2,CAND1,TOP1,SUMO2,PPP1CB,ATG16L1,PABPC5,EHHADH,GIT2,CDK1,RPA2,PPARG,EMC9,GRM2,EP300,SNRPA,RPA3,AATF,PSENEN,HDAC3,HMGB1,STAU1,RNF40,ANAPC15,H2BC9,ATG101,SNRPB,PPP1CC,MYC,HNRNPC,CUL3,DHPS,ELAVL2,NRP1,PEA15,RIT1,PSMD14,EZH1,POLR2B,DYRK1A,ESR2,MATR3,SPCS1 |
| 5.090e-06 | -12.19 | U2-type precatalytic spliceosome | cellular component | GO:0071005 | 50 | 30 | 19108 | 5553 |
SNRPE,SNRPG,PRPF31,SNRPB2,IK,LSM4,PRPF4,RNF113A,LSM2,SNRPA1,SNIP1,SMU1,RBMX2,DHX16,MFAP1,LSM6,SNRPD2,SF3A1,ZMAT2,SF3B5,SF3B4,LSM8,TXNL4A,SF3B1,SNRPB,SNRPD3,SNRPD1,LSM3,LSM5,MAGOHB |
| 5.097e-06 | -12.19 | CHMP2A (charged multivesicular body protein 2A) | protein interactions | 27243 | 107 | 52 | 19454 | 5460 |
RAB2A,MYC,BTF3,TUFM,UFD1,CHMP5,ATP6AP2,CINP,PELO,DLST,CLDN3,VPS4B,CHMP1A,ZNF574,STAMBP,TXNL4A,USP8,CHMP2B,UNC45A,RPA3,SMAD4,SKIC8,VPS4A,DDX1,CDK12,TGFB3,USP15,RAB5C,ATG7,XPO1,NOL4,EIF3D,TRIM35,EIF2B5,CGAS,ERLIN1,CHMP2A,ZBTB2,CHMP4C,RBPJ,RAF1,TBK1,E2F4,CHMP1B,KRAS,MRPS18C,VTA1,PDE2A,TFG,HNRNPDL,MYO1B,SNAP23 |
| 5.101e-06 | -12.19 | DENND5B (DENN domain containing 5B) | protein interactions | 160518 | 17 | 14 | 19454 | 5460 |
PRNP,VIRMA,NTMT1,STX7,RAB35,LDLR,GJA1,PSMD14,LAMTOR1,GRB10,RAB11A,ATG16L1,CSK,ACTR1A |
| 5.123e-06 | -12.18 | ECHS1 (enoyl-CoA hydratase, short chain 1) | protein interactions | 1892 | 227 | 95 | 19454 | 5460 |
USP14,TUFM,HMOX2,OAT,YPEL5,DNAJC19,UBE2H,CHCHD4,ACOX1,SUCLG2,CDC42,CDK7,CAPN1,MTRES1,GFM1,BAP1,GRPEL1,CRYZ,SLC25A51,GRSF1,MOV10,ISYNA1,USP15,TMEM70,CHCHD1,NT5DC1,SSBP1,SYNCRIP,COX4I1,UBE2N,DBT,AURKAIP1,METTL15,UBE2V1,CMPK1,MRPL11,RAP1A,GFM2,SERPINA1,NHERF1,AGA,IDH1,PSMB10,FASTKD5,RIGI,CAMK2G,TF,PSMD1,AUH,MTG2,PMPCA,TXNRD2,YWHAZ,S100A6,TACO1,MTG1,CCDC90B,ENO2,PARL,PRRC2A,STXBP1,LAP3,CNDP2,AKR1A1,CTBP1,ACAA2,HSPA8,ATPAF2,NGRN,EXD2,GINS3,HSCB,EMC1,FXR2,OXCT1,PPIB,PSMD3,MTRF1,MRPS26,RHOG,PPM1B,AGR2,GATD3,SLMAP,RMND1,SUMO3,RAF1,CLDN12,EZH2,PDHA1,HINT2,COX8A,HSPD1,AHCYL1,IMMP2L |
| 5.123e-06 | -12.18 | MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4) | protein interactions | 9448 | 227 | 95 | 19454 | 5460 |
DDRGK1,YWHAG,INSYN1,XPO1,YWHAH,ZCCHC10,RSBN1L,PDCD10,NCK1,RHOG,GJA1,PPP2CB,GYS1,RAB35,TNIK,EGLN3,CACYBP,SLMAP,DIRAS3,PPP2R1A,MOB3C,CRKL,ZRANB2,CTTNBP2,FLOT1,RPS27A,G3BP1,KRAS,EPHA4,RAB11A,SFN,CUL3,NTRK3,HSP90AA1,H1-10,RHOB,BRCA1,LAMTOR1,MANSC1,FBXO22,DYNLL1,FANCD2OS,RAP2A,STK26,STX7,STAU1,UFL1,H2AC14,STYK1,CDK12,RAC2,RPL32,HRAS,H2AZ1,CAV1,CWC15,ARF6,TP53,DISC1,RBM34,CBX3,IGF1R,SIKE1,LTBR,PTGES3,CNOT6L,FN3KRP,CTNNBL1,DNAJC5,PPP1CC,ARHGAP21,SMARCA5,RPF2,FGFR1OP2,UBE2H,STK24,BICD2,RAP2C,SYT2,CSNK2B,MOB4,CTNNA1,VIRMA,CTTNBP2NL,RHOJ,PRKCE,CCL3,ACACA,FGFR1,RPA2,MRPS34,TEX264,RPA3,BRIX1,FBXW7 |
| 5.123e-06 | -12.18 | endosome membrane | cellular component | GO:0010008 | 569 | 214 | 19108 | 5553 |
RAB11A,SYNDIG1,VPS28,DIO3,RHOB,AP5M1,CLVS1,TMEM108,PIP4P1,CD1D,RAP2C,MRC1,SNX2,CFTR,CD1B,ACAP2,PARM1,TSPAN15,OCRL,TBC1D5,REP15,NDFIP1,SNX18,STARD3NL,AP2A1,RNASEK,RHOU,EHD4,LY96,UBAP1,RAB4A,SNX1,SNX17,SNX12,ATP6V1D,FURIN,SLC6A4,TASL,UBA52,CPTP,CLIP3,AP1G2,AP2S1,ABCC5,TOM1L1,PDLIM4,SCYL2,TAB1,ADRB2,RAB11B,MYD88,VPS18,ZMPSTE24,CHMP2B,CD1A,TMEM30A,PLD3,SLC1A1,TICAM1,HPS6,VPS16,TOM1,LAMTOR1,SLA2,RAB31,TSG101,TLR3,KCNH1,RAB27A,CLCN6,OR51E2,PLEKHF2,ARF6,TMEM165,VAMP7,TMEM45B,SCAMP2,MCOLN1,NTRK2,CHMP2A,RAB13,LAMTOR2,TLR7,RAB35,SPG21,FCMR,CDIP1,IRF7,RAB5C,ATG9A,OPTN,ATP6AP2,VPS39,APH1A,SCAMP5,ARHGAP1,VPS4A,PML,IRAK4,BACE1,LAPTM4A,GNPNAT1,ATG16L1,AP2M1,PCSK9,PLA2G4B,TLR9,MMD,LAMP3,STX12,FCGR1A,VTA1,MARCHF3,CTSD,LAMP5,SNX14,SLC11A2,STX7,ABHD6,LAMTOR3,RNF167,PSEN1,DKK1,AQP4,LITAF,RAB14,VAMP8,CAV1,RHOBTB1,VPS26A,LAMP2,RAB8B,PLEKHF1,NSG1,UBE2D3,UBXN6,ATP6V0E1,SLC31A1,LRP6,RPS27A,TF,RAP2B,ABHD17A,TMBIM1,VPS4B,GOSR2,ATP6V0B,EHD1,SNX3,CORO1C,BECN1,TMEM106B,TAB2,UBB,VPS33A,STX6,GRIA1,GPNMB,INPP4A,FGD2,CD164,SNX20,RAB5A,MTMR2,NCSTN,HGS,B2M,SLC38A9,LDLR,WDR44,CHMP1B,ATP6V1A,CD274,CHMP5,TLR4,AP5S1,CLVS2,MREG,PDIA3,LDLRAD4,TRAF6,CD1C,TICAM2,PIP4P2,VAMP3,SLC48A1,HSD17B6,TMEM59,CMTM6,EHD3,WDR83,SNX5,CD63,CX3CR1,ITM2B,EPHA4,TFRC,SNX10,RAP2A,CHMP4C,RAB22A,NCDN,VTI1B,BOK,FIG4,CHMP1A,RAB23,VAC14,MYO1B,USP8,PSENEN,RAP1A,CD14,TLR8 |
| 5.131e-06 | -12.18 | MACROH2A1 (macroH2A.1 histone) | protein interactions | 9555 | 424 | 161 | 19454 | 5460 |
AHCYL1,GOLGA7,POLDIP3,GTF3C3,TRIM37,HMGN4,RUVBL1,VDAC1,KRAS,G3BP1,TRIM26,SREK1IP1,RPS24,RUVBL2,RHOBTB1,RBPJ,CCR1,MTA2,SMARCB1,H2BC1,PDHA1,GDI2,CHMP4C,TUBB4B,EZH2,TRAF2,SOX2,B3GNT2,TOP3B,MAX,RAF1,CETN2,DIRAS3,RHOH,HNRNPL,RPS10,COPS2,EED,NRSN1,FBXO32,SIN3A,PPM1B,KDM2A,RHOG,NT5C2,PTDSS1,PRDX1,IFI16,HMGA1,GPM6A,STAU1,SRSF2,HADHA,XRCC5,NKAPD1,ADNP,SDC2,PPARG,ZNF428,RND2,SSBP2,H2BW1,WDR77,APEX1,ESR2,CBX5,POLR2B,SNRNP40,FBXO22,TUBB,CAVIN2,MATR3,ZMYM2,RAN,ATXN1L,DLST,PHF12,H1-1,CDKL2,COP1,LMNB1,RHOB,ZCRB1,BRCA1,SMARCE1,RIOK2,CUL3,MYC,MSH6,THRAP3,VRK1,HUWE1,H3C1,RPL3,MAP1B,DDR1,SNIP1,NUPR1,HBP1,NECAP1,DMAP1,CBX3,RPL15,ZMYM3,H2AX,CDC5L,TOP1,CGAS,KRR1,SCG5,H2AZ1,SSBP1,AGPAT1,USP15,BRD3,AKAP8L,H2AC4,CHCHD1,MED27,SUV39H1,COPS5,DPP4,GRSF1,MBD3,PIAS1,TOMM20,NUCKS1,HMGB1,GTF2I,HELLS,RPA3,MACROH2A2,RPLP0,METTL14,STX17,LMNA,RPA2,CDK1,GTF3C4,KDELR2,CDC42,TPT1,DEK,SMURF1,RPL13A,ZNF622,HPF1,TRIM24,TUBA1B,ZNF330,CCNF,MAPRE1,UBE2H,ATP1A1,SPOP,MECP2,AR,DNAJC8,USP14,H2BC9,SMARCA5 |
| 5.143e-06 | -12.18 | regulation of cellular catabolic process | biological process | GO:0031329 | 455 | 178 | 18204 | 5365 |
MIR16-1,RNF152,SLC25A5,CTTN,TRIM23,DAP,PHF23,SUPT5H,TMEM39A,SH3GLB1,EXOC8,PIP4K2C,TMEM59,CAPN1,FEZ1,HSPB8,TBK1,STK38L,MYLIP,SLC25A4,TRIM32,LACRT,TRIM6,LAMP3,ATG16L1,TNF,IL10,ATP6V0E1,RNF5,HDAC6,ABHD5,FBXW7,POLDIP2,PLEKHF1,TRIM5,PYCARD,STK11,STUB1,HMGB1,ORMDL3,CDK5,RALB,CTSA,MIR195,LYPLA1,BNIP3L,TIMP1,WDR6,TICAM1,FBXO7,APOC2,GAPDH,SCFD1,UFL1,IFI16,RAB39B,PIK3R2,ATP6V1E2,KLHL22,TSPO,SESN2,ROCK1,TOM1,ATG101,USP30,LEPR,RRAGA,PIK3CA,CCNY,FKBP8,IFNG,TP53,TAB2,GNAI3,DDIT3,LEP,TRIM27,SQSTM1,RNF41,PIK3CG,TFEB,TRIM21,MTMR2,RB1CC1,TIMP4,SH3BP4,ADRA1A,PTPN1,GSK3A,IDH1,PARL,BAD,RGMA,NLRP6,ATP2B4,TSPAN15,PCSK9,MIRLET7B,BECN1,CNR1,CISD1,MET,CSNK2A1,TRIM22,TSPAN5,RHEB,BAG3,SEC22B,SESN3,TRIM8,MT3,EP300,SNX5,SVIP,IGF1,PACSIN3,ATP6V1G2,BOK,SNX18,CRYBA1,VPS26A,SNX33,ADRB2,C9orf72,MTDH,PTPN22,USP13,ATP6V1C1,IL1B,AKT1,ATP6V1G1,HP,PIM2,OPTN,IFNB1,CPTP,ATP6V1A,RRAGB,FURIN,SNRNP70,PSEN1,MTM1,MIR21,ZMPSTE24,HTRA2,TNFRSF1B,TLR9,TSPAN17,MCL1,IL4,EXOC1,FLCN,EIF4E,TIMP3,TP53INP1,HSPB1,NUPR1,DAPK1,ATP6V0B,TBC1D25,TRIM68,PAFAH1B2,EEF1A1,ATP6V1D,ETFBKMT,HAX1,DAPK3,WDR45,GPR137,PPARA,CDK5R1,VPS26B,TRIM34,AKT2,VDAC1,DRAM1,LDLR,HTR2A |
| 5.165e-06 | -12.17 | positive regulation of canonical NF-kappaB signal transduction | biological process | GO:0043123 | 209 | 92 | 18204 | 5365 |
LPAR1,TNFSF10,TLR3,TRIM68,DDX1,TAB2,TRAF3IP2,CLEC7A,MAP3K3,PRL,TRIM34,BCL10,IRF3,FLOT1,TRIM21,PELI1,FASLG,TLR4,SLC20A1,CAV1,S100B,TICAM1,RBCK1,CLEC6A,MAVS,IKBKB,GAPDH,EDNRA,TMEM101,PIM2,VEGFA,CD36,TLR9,TRIM52,MYD88,IRAK4,CCDC22,ATP2C1,CD4,ADIPOQ,TNF,IL1A,CX3CL1,MUL1,LTB,TRIM32,TRAF2,CX3CR1,TMEM106A,TRIM62,TRIM8,TRIM6,EDA2R,TFRC,BIRC2,UBE2V1,CXXC5,IL1B,CD40,CCR7,TLR6,ZDHHC17,TMED4,MTDH,LURAP1,TRIM5,TFG,PPP5C,FKBP1A,IRAK1BP1,NUP62,JMJD8,BST2,TIRAP,DHX15,ILK,FBXW11,PRKCE,PRKCB,GPR89A,TRIM22,GJA1,CCL21,TRAF6,NDFIP1,TICAM2,TIFA,LTBR,CCL19,LITAF,UBE2N,TBK1 |
| 5.166e-06 | -12.17 | STX7 (syntaxin 7) | protein interactions | 8417 | 654 | 235 | 19454 | 5460 |
TMEM87A,TYW5,EFNB1,SLC20A2,KRAS,VAMP8,STBD1,RAB4A,SWAP70,RAB35,RAB31,STX5,RAB1B,AFTPH,VAMP7,RAB5C,LAMP2,DDRGK1,PPFIBP1,TMEM106B,JAGN1,RAB5A,GOSR1,SLC31A1,BET1,GOSR2,MTMR6,USP6NL,LMBR1L,VDAC2,FAM83B,RETREG3,ATP6AP2,TM4SF19,STX16,LAMTOR1,SERPINH1,SLC38A1,PALM2AKAP2,CYBRD1,STX18,SLC16A1,RAB3B,AKAP12,SLC6A8,RAP1A,PREB,UBL4A,SNAP29,TMEM205,UBIAD1,NHERF1,TFRC,EXOC3,CAMLG,RAC2,SLC39A10,ADD1,RAP1B,FCHO2,SVIP,VTI1B,SLC38A2,TMPO,STX6,LMAN1,DPP4,NOS1AP,BAP1,TEX264,TMX2,ARFIP1,RAB9A,LPAR1,NAPG,CLDND1,SPTBN1,CDC42,VIPAS39,USE1,RPA2,LEMD3,ATL1,NECTIN2,STX10,SRC,ACP2,VAMP5,SUGP1,RAB2A,GORASP2,SLC6A6,DNAJC5,EXOC5,ARHGAP21,RIC3,CHCHD4,STXBP6,CISD1,SNX5,ATP1A1,SCYL2,SEMA4C,E2F4,MACO1,MARCKSL1,RAF1,IFNGR1,GTF2E2,STIM1,VPS33A,VAMP2,ITGB5,STX12,WDR6,GJA1,SNX2,SPTAN1,SNX1,OCRL,CX3CL1,WDR44,RAB11B,FAM174A,RHOG,CDK5RAP3,LRRC57,STX1A,C2CD2L,SLC35F2,PMAIP1,TOR1AIP2,NOTCH2,EHD1,RND2,VPS18,VAPB,ARF1,FAM91A1,AP2M1,LAMTOR3,MB21D2,RAB11A,TM9SF4,VEZT,NIBAN2,MAP3K21,MYO6,LMNB1,RHOB,VMP1,SCFD1,DLG1,NSDHL,EHD4,STX8,RAB1A,SNAP23,SEPTIN7,NOC4L,VPS16,ADD2,SFT2D2,CTNND1,CCDC47,SLC29A1,LBR,PPIF,SOD2,EHBP1,HRAS,SRPRA,PTPN1,CDCA3,HSD17B11,ALCAM,ARF6,CAV1,ATP5MG,TMEM199,RELL1,LAMP3,HM13,ESYT1,TIAM1,TMEM184C,OSBPL8,ZKSCAN1,RPA3,RTN4,MTDH,SLC7A1,GTF2I,NF2,YKT6,TMEM209,CDC42EP4,CHMP2B,SEC22B,ARHGAP1,PIP5K1A,UBA52,RABL3,CNP,EHD3,CDK7,SYNRG,SLC12A2,GOLGA5,PICALM,PTP4A2,JUP,LMNA,AP1AR,SMAP2,CTNNA1,SCAMP2,MRPL53,GAB1,VAMP3,YES1,SNX3,RHOJ,RAB14,MGST3,SEC63,FERMT2,SH3BP4,SEC13,CREB3,HMOX2,DEPDC1B,NRP1,NAPA,EPHA2 |
| 5.200e-06 | -12.17 | rough endoplasmic reticulum | cellular component | GO:0005791 | 57 | 33 | 19108 | 5553 |
SEC61A2,SEC62,LRAT,SRPRB,PTGDS,STX17,STAU1,CCDC47,RPN1,TMCC1,TMEM97,PSEN1,MACO1,RAB14,FKRP,RPS29,HCRT,RPS26,RPL18,SEC61A1,HM13,RPS28,RPL6,RPS23,SEC61G,RANGRF,SPPL3,SRPRA,SEC63,RP9,SEC61B,RPL27,RPL4 |
| 5.210e-06 | -12.16 | negative regulation of immune system process | biological process | GO:0002683 | 529 | 203 | 18204 | 5365 |
ABHD17A,HMGB1,SYK,TMBIM6,HFE,BCL6,CXCL12,FCGR2B,EMILIN1,NFKBIL1,FBXW7,DUSP10,PSMA1,STAP1,SARM1,VSIR,ADIPOQ,TNF,TWSG1,MUL1,XCL1,DUSP22,IL10,MIR24-1,CX3CR1,PDCD1,RHBDD3,GPAM,TRIM32,CCN3,YES1,DUSP1,MIR17,CLEC12B,MIR222,CCL25,EIF4E2,CCR2,IRF4,SFTPD,DPP4,CTLA4,PDCD1LG2,TRIB1,CCL2,TNFRSF14,IL2RA,MIR105-1,ARG2,NPY5R,TBC1D10C,CGAS,PRDX2,MMP28,HSPA8,ANGPT1,PSMB4,ADORA1,SRC,TMEM176B,FGL2,SQSTM1,TRIM27,TLR4,THY1,CDK6,TRIM21,MIR140,SEC14L1,CD200,SDC4,IDO1,TNFAIP6,LGR4,MIR34A,UFD1,PIK3R1,YWHAZ,TNFAIP8L2,IRF1,SLA2,GPNMB,PPARG,IFI16,BPIFB1,PTGER4,CSNK1A1,FBXO7,LGALS3,CNOT7,MIR181C,YTHDF2,UBASH3B,LPXN,SAMHD1,RNF115,WASL,COL3A1,PTPN22,TAPBPL,C1QC,TGFB3,AKT1,TRAFD1,TLR6,ISG15,STAT6,SELENOS,GREM1,ADTRP,TGFB2,DUSP3,TNFAIP3,CTNNB1,GPX1,CCL21,MIR20A,CD59,NDFIP1,STAT2,SOX9,FAM3A,IL2,MIR221,MIR130A,SNAI2,TSC22D3,CNR1,DLG1,CARTPT,KLRD1,BANF1,NLRP6,CD200R1,MIR200C,CCL28,MIR708,PLA2G5,ACP5,MIR125A,NR1H2,BST2,TOB2,OAS1,TMEM176A,CCL3,MIF,LILRB1,FOXP3,CD274,LDLR,DDT,USP15,PRNP,BTN2A2,GPR137,PELI1,MIR223,LRRC14,IL12B,FGR,ELF1,MIR185,TLR3,SFRP1,MYC,USP38,PADI2,GPR17,PYDC2,CD86,SOCS5,IL20RB,RUNX1,PLCB1,SH2D1A,IL4,LST1,TCTA,SFN,MIR149,LILRA2,CD46,LILRB4,MIR146A,INHA,MIR21,IFNA2,MIR30B,CPTP,TRIM11,IFNB1,TYROBP,LYAR,RC3H2,NMI,FURIN,MAVS,SERPINB9,TAX1BP1,CBFB,CD80,LYPLAL1 |
| 5.221e-06 | -12.16 | positive regulation of macromolecule biosynthetic process | biological process | GO:0010557 | 2592 | 860 | 18204 | 5365 |
IL15,MIR769,TLR1,BCL9,FGF23,EIF3E,MTPN,VEGFA,SLC38A2,MTA2,IL23A,CCAR1,PIK3R2,SETD4,KLF1,PIK3R1,NR2E1,CCL1,OSM,FZD4,NIBAN2,ELK4,DEK,SOX14,TCP1,TRUB1,CAMK1,IL17F,TAF10,APEX1,SUPT4H1,ROCK1,ETV6,IL18,UQCC2,WRAP53,ELK3,CD58,CD40LG,PIK3CG,PDE4B,TFEB,MIR140,CHCHD2,CCL2,CLEC9A,PSMC5,IGF2BP1,MAP2K6,WBP2,PDE2A,POU1F1,NUP62,ARL2BP,MAPKAPK5,PIH1D1,MIR16-1,SERTAD3,APOBEC3A,MRPL12,ZNF287,CYP1B1,MIR183,TLR2,PIAS1,RNF10,VAMP3,AKAP8L,STAT5A,VIP,XRCC5,CYRIB,TBK1,VSIR,SPTBN1,CD2,NIF3L1,TCEA1,MIR101-1,MED9,UBE2L3,TRMT112,TRIM32,BIRC2,YES1,SERTAD1,LAMP3,PRKAB1,MED23,NR1I3,NLRP1,SYK,FGF16,PITHD1,HILPDA,BOLL,CD40,ACVR1B,MED10,SGF29,NOG,TESC,EAF2,NME2,PRDX6,FOXA3,MED22,TRIM5,ALKBH4,APOBEC3C,CREB3,RIGI,PAX6,SSBP3,MAD2L2,SMYD3,WNT10B,CLEC6A,CD80,UCN,GABPB1,GTF2A1,PRKAG1,MED27,TP53INP2,HDAC3,ADM2,MLLT6,SMARCD3,TLR9,PLCB1,ZBTB16,ZNF24,DNAJC3,MEF2B,ZNF507,CDC73,MIR223,ZNF513,DDX1,FCER1G,MMP14,ELF1,ID4,AGPAT1,EFCAB7,IL6,TRAF3IP2,TP53INP1,SOX21,PADI2,PAIP1,CD86,ACTL6A,PPP1R12A,AKT2,CD274,FOXP3,UHMK1,E2F4,SF3B4,HAX1,TENT4A,SMARCE1,TAF11,E4F1,NR1H2,FGF1,MIR125A,CDK5RAP3,ATF1,RGMA,MET,XBP1,PID1,KIT,IL2,MIR130A,CYTL1,HNRNPAB,AR,SOD1,ENY2,DKC1,HMX2,NFKBIA,IGF1,SIRT7,CALR,TCF23,MIR675,MAX,VDR,RBBP4,TOX,NEUROD6,TEF,CREB3L4,MT3,PPP3CA,WNT7A,VSTM2A,MIR182,ELAVL4,CEBPE,TGFB3,IL1B,DYRK1B,AKT1,AGR2,FUBP3,TLR6,RPS4X,ITGA2,SERTAD2,CCT7,RPL26,HMCES,C1QTNF1,KPNA2,LUM,ZNF668,TRIM44,TRIM15,B2M,GTF2I,HEXB,DROSHA,PRIM2,LHX2,TRIM52,TRA2A,PLGRKT,FOXJ3,RHOG,RBM3,MIR212,EPCAM,MDM2,ACTL6B,TP53,SOST,NCBP2,NEK7,ZNF574,ZNF473,TRIP4,HSPA8,CSRNP3,RAP2C,BAG2,PAX9,ZBED3,KLF4,TLR4,JADE1,ARF4,MED4,TENT5C,SUPT5H,NFYA,NDN,CDK9,ILK,NLRP2,RB1,CITED1,MIR17,ZBED4,GJA1,CEBPG,CNTN1,NLRP3,IRF4,FOXC2,AIF1,CLDN3,NEUROG2,TNF,HMGA1,ACTB,FGF3,RBPJ,SF3B1,XCL1,NGRN,CX3CL1,FCGR2A,ING1,PHB1,RUVBL1,FGF7,TOP2B,HFE,SH3BGRL,PLAC8,ITGB8,HINFP,MED11,EMILIN1,MZB1,IL1RAP,GTF2A2,CCT8,LURAP1,TYROBP,GPBP1L1,KANSL3,MAVS,ZBTB17,TADA1,RUVBL2,ING2,HSPA5,IL20RB,MDC1,TAF5L,ILF2,IL4,MYD88,FAM98A,MIR149,CD46,NKRF,CD81,DGCR8,MIR146A,NLRP9,CCL5,RORB,PELP1,AKAP12,DYRK2,MOSPD1,DEFB124,TLR3,SFRP1,RTRAF,AGO1,NUPR1,HNF1B,CCL3,MIF,YWHAH,LILRB1,EIF5A2,IL12A,MIR132,BCL10,MAP3K12,BARX2,IRF3,HEY2,IL6ST,GTF2F2,CSF2,RFX4,KLF12,SETD7,ZBED1,TLR7,EDF1,IL5,RGMB,PRPF19,NR1I2,KDM1A,CDC5L,PRMT2,IRF8,HGS,MIR511,MAP2K1,HDAC5,ANKRD49,NUCKS1,HNRNPA0,SUB1,PAEP,HOXC4,SOX9,STAT2,TOPORS,RBM23,CNOT6,SF3B5,DNAJB9,PARM1,LRP3,MAP2K3,RERE,LTB,SCAND1,TRIM8,RPRD1B,TLE1,MSL2,RFC2,SPP1,HOXB1,DHX9,DKK1,CCR7,STAT6,ISG15,UAP1,ZNF345,ADRB2,HCFC2,MBD3,HAND2,PRDM4,NFE2L2,TICAM1,SOX3,SMAD9,MPV17L2,SMARCB1,MECP2,BMPR1A,SEMA7A,TFE3,BMPR2,EXOSC3,MIR29A,AFAP1L2,UTP15,IRF1,PQBP1,CCT5,LMO3,NTRK2,TLR8,IFI16,NTRK3,ZNF319,METTL14,ACTR2,EIF2B5,RFXANK,IFNG,MED17,MEF2A,STK16,NRDE2,PTGES3,ANGPT1,ZNF609,SMARCA5,SRC,PHB2,ZNF175,LEP,HNRNPK,SQSTM1,POLR2G,ATF4,CD200,TRIM21,CHI3L1,FOS,HCLS1,TFCP2,IRF2BPL,BMPR1B,TERT,NFKB1,HLF,PABPC1,PLP1,SUPT3H,CD38,NEK2,TICAM2,NDP,TRAF6,FXR2,TLR5,CCL19,RNF40,PLAGL1,PCBD1,CSRNP1,SMAD3,CRTC2,EIF4A3,KMT5B,TAF9,TUSC2,HNRNPD,WNT2,SELENOK,TFRC,TRIM62,CLU,MIR205,MED30,KLF10,RPS7,FCGR2B,PKNOX1,ATF3,NKX3-1,STAP1,MED29,LYAR,ELK1,CD36,RBBP9,POLR3F,POU5F1,TCF21,IREB2,RMND1,FOXD3,MIR33B,MIR548C,DNM2,CREBL2,RGCC,SYNCRIP,MYBL2,LILRA2,ECD,MIR21,MIR30B,STOML2,FOXP1,THRAP3,RNF14,IL12B,UBE3A,FGR,RNASEL,POLR3B,LDB2,RSAD2,RFX5,GTF2F1,ERP29,ZFP64,ZNF267,HAS3,PNP,JUN,PRL,JUNB,OTX2,DMAP1,HSPD1,LDLR,ENO1,ZNF263,NEUROD2,MTA3,CXXC1,RXRG,IFNGR1,FLOT1,PPARA,PELI1,LMO2,JAK2,MED31,MORF4L1,TIRAP,LRP6,STAT1,PKIB,CAND1,GSK3A,KPNA6,LACC1,DVL2,RAMP3,RAB27A,CD34,LMO4,ODAM,GRIA1,CREBZF,TNFSF13,AATF,RLN2,MLLT11,MIR206,CD14,EIF2AK2,PSMC3,SS18,CDK12,MSN,RRN3,TRIM24,RFC3,PDCD10,EP300,SNX5,KARS1,WDR77,NAA16,PIK3R3,EIF3D,HYAL2,BACH1,SHLD1,CTNNB1,TMEM106A,KLK5,LMNA,UBE2V1,PRMT5,TANK,SMAD4,INO80E,EPO,SLC6A4,RAD21,NR4A2,CNOT7,IL34,MYRF,IKBKB,TGFB1I1,EGR1,GAPDH,NFYB,NCSTN,ESR2,YTHDF2,UPF3B,IER2,EZH1,RFXAP,IL7,ITK,RNF20,ZNHIT1,PGR,MIR106A,RNF187,PRKCQ,JUP,PPARG,SP1,RPL23,SFRP4,PTGER4,CCNA2,TAF7,CXCL8,TENT5D,IDO1,IL21,CLEC7A,VPS72,MITF,ITGA6,IL13,MIR34A,UBP1,HELT,SRSF1,P2RY1,SCAMP5,VGLL2,ACSS2,SIX5,FGF22,PTPN11,TOMM70,DDIT3,TRIM27,TFPT,CDK6,DNAJC2,ZNF593,CXCL10,TNFRSF14,USP16,RFC4,SPHK2,TRA2B,FBXW11,OGG1,CGAS,TFDP2,BRD3,LDB1,ACVR1,CCR2,POMT2,PLSCR1,MIR657,RBBP7,LBH,FGF17,NAA15,POLDIP3,CRLF3,ADIPOQ,DDRGK1,PTGFR,MIR640,IL10,ROCK2,H2AZ1,YAF2,RAF1,ARMCX3,TRAF2,MIR145,MSX1,RFC5,NMBR,LY96,TRIM6,EEF2,RPS3,YTHDF1,HMGB1,SSBP4,ZNF770,INO80C,GABPA,S100A10,LARP4B,BATF,PYCARD,MIR23A,HRAS,ZNF304,AGER,IFNB1,CAV1,MEPCE,MEAF6,TNKS,RAB1A,CD28,CBFB,HSP90AB1,PIM2,MSTN,SUPT7L,MEF2C,IRF9,ZMPSTE24,RUNX1,IFIH1,RBM22,BUD31,BRCA1,SLC38A3,SMAD2,TAF2,MIR324,SNRNP70,ZGLP1,APOBEC3F,RPS27L,TNKS2,PSEN1,EGR2,CD4,GPSM3,G3BP1,SPON1,CASK,HNRNPA1,SSBP2,DLX1,WWP2,CREB1,FRMD8,MYC,MARS1,HSPB1,PSRC1,CD83,SASH3,PDCD5,RPS6KA4,OSR2,CDK1,APLN,ATP6AP2,INPP5K,DDT,HTR2A,NFIL3,HSP90AA1,MED21,SMAD5,TNFSF8,IRF7,SMAD1,CCT2,RIT2,MACROH2A1,ACTN4,SHC1,PRKCB,CTBP1,PAGR1,FOSL2,LTA,SETD3,TRAF3IP3,OAS1,HNRNPC,COPS5,CIRBP,TADA3,NFE2,CCL21,TRIM22,BAZ1B,AIP,MTF1,MAFG,LITAF,PICALM,CDK7,PYM1,DPY30,ACTA2,RASL11A,SRPK2,KRAS,NOTCH2,MIR144,IL1A,CHP1,TGFB2,PCNA,FGF10,NCK1,IL2RG,IRF6,ZBTB38,TF,NFKBIB,WASL,SOX2,PTPN22,IRF2,TRIM37,DYRK1A,PXYLP1,ABHD14B,PIWIL2,CDH13,KLK3,ZBTB18,GREM1,CREBBP,PROX1,ADTRP,MTDH |
| 5.227e-06 | -12.16 | LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 123169 | 265 | 108 | 19454 | 5460 |
MRPL57,CMAS,PSMC1,COIL,SNRPA,SLU7,DCTN3,HADHA,EP300,MRPS18A,TMEM115,PSMB7,ACTL6A,SUPT4H1,PSMD6,ACTB,UMPS,ZNHIT6,VPS72,MRPS25,TAFAZZIN,H1-1,SYCE3,SNRPB,PSMD1,MRPL16,SSRP1,COPS4,PPWD1,PSMD12,SDHC,LTO1,RPL31,SRSF7,RUVBL2,POLR2C,SUPT5H,MAX,PPP2R1A,SOX2,CHMP2A,RPLP2,DDX23,SKIC8,CDC23,MRPS35,TAF7,UBXN6,CTNNB1,XPO1,SLC7A1,KDM1A,MARS1,SNAPC1,DDX46,RPL27,RPA3,PRIM2,TCEA1,PGK1,ELOF1,USE1,DCTN4,CDK1,TFB1M,SEC22B,AKR7A2,GTF2H4,MRPL10,MRPS21,DYRK1A,UBA3,ZNF330,SYT2,MRPS28,CSNK2B,MRPS16,UBE2H,CDC73,CIAO1,PTPN11,CDC16,PPP1CC,GPRASP3,REXO2,H3C1,PTGES3,MRPL22,PDRG1,RPL3,MRPL36,POLR2G,MRPL33,CENPM,NDUFA2,RRM1,TOP1,MRPS23,MRPL24,CAMLG,SSBP1,MRPS9,RPL24,SLC35A1,CDK12,RBM17,KARS1,CSNK2A1 |
| 5.275e-06 | -12.15 | BMH2 (14-3-3 family protein BMH2) | protein interactions | 851676 | 187 | 81 | 19454 | 5460 |
RCBTB1,CSNK2B,ALG2,CTTN,STUB1,MAT2B,IDE,ACTB,TXNDC12,GMDS,TUBB,ATP5F1B,MCM3,GMPS,ATP5F1A,MAT2A,CTSD,RBM7,SERPINB1,PRDX6,HSPA8,TXNL1,EXOSC4,SKP1,HSPA5,SMC4,FBXW7,EEF1G,PFKFB2,CSNK1A1,ACACA,KLC2,HSP90B1,KRT8,SEC23A,PPP2CB,EEF1B2,PSME2,G6PD,DHX15,TCP1,KCTD3,NT5C2,TPM3,GAPDH,EDC3,PDIA3,PRDX1,YWHAB,DDX1,H2AC4,TIAM1,IGF1R,PDIA6,PSME1,PABPC1,ZYX,HSPD1,TFG,PRDX4,FN3KRP,RPIA,TF,HNRNPK,RUVBL1,CNOT7,LASP1,EEF2,TUBA1A,ACTN4,EEF1A1,PSMB9,TXNRD1,CDK4,ACO1,CRKL,TBC1D4,PPME1,NME1,BZW2,HSPA13 |
| 5.293e-06 | -12.15 | NSUN2 (NOP2/Sun RNA methyltransferase 2) | protein interactions | 54888 | 268 | 109 | 19454 | 5460 |
PPP1R12A,MAP1B,RAB1A,IGF1R,THG1L,TOM1,FBP1,STRBP,ACTR2,SH3GLB1,NUPR1,GTF2B,AIFM1,DFFA,CD274,ADD1,LDLR,FZR1,CAND1,RPS16,CDK9,CALR,ERCC3,COPS5,GTF2E1,HDAC6,SNRNP70,BAP1,LIN7C,RPA3,PPM1G,SOD1,PNO1,SIRT7,ARPC2,RNF113A,CCR4,CFTR,RPRD1B,RPA2,LMNA,METTL14,FGFR1,PSPC1,CREB1,CCNF,MSN,YES1,ROCK1,DYRK1A,AR,NRP1,MAPRE1,CALU,UBE2H,S100B,NUDT5,UBE3A,TNF,G3BP1,ROCK2,RPS27A,PFDN1,CSNK1E,RAF1,HEXA,EZH2,PDHA1,RPS11,MOB3C,PPP2CB,PHB1,XPO5,SUMO2,PIK3R1,IFI16,WWP2,PFDN5,NDC80,DDRGK1,AGR2,DDX39B,LCA5,DNAJC3,HSPA8,THBS3,UFL1,STAU1,BET1,CDKN1A,KCTD12,PALS2,USP39,PIH1D1,CNDP2,LMBR1L,TSN,MAT2B,MAD2L2,RPL10,MYC,RAB11A,PSMA4,CUL3,RNF40,PSMD14,OSGEP,DNAJB6,SERPINH1 |
| 5.343e-06 | -12.14 | RUNX2 (RUNX family transcription factor 2) | protein interactions | 860 | 76 | 40 | 19454 | 5460 |
TLE1,CCNB1,WWP2,CREBBP,FEM1B,AR,SUV39H1,CTNNB1,BAG3,RUNX1,HDAC6,BGLAP,SMAD2,ALYREF,STUB1,CBFB,SMAD3,RB1,STAT5A,SMAD5,SMURF1,TP53,SOX9,MSX2,SMAD1,DET1,SOX2,JUN,WWP1,CDK1,JCHAIN,XRCC5,FOS,PML,BMPR1A,DVL2,HSPD1,EP300,HDAC5,HDAC3 |
| 5.344e-06 | -12.14 | KIN (Kin17 DNA and RNA binding protein) | protein interactions | 22944 | 66 | 36 | 19454 | 5460 |
RPL18,RPLP0,RPA2,RPL27A,EIF2D,SAR1B,METTL22,RPL4,STAU1,KRAS,DDX5,RPL3,PCNA,PABPC1,RPL31,SNRPA,MIR363,MIR1-1,COP1,PLCL1,SNRNP70,DDX23,DDRGK1,SNRPB,RPL6,RPL7A,MYC,RPL19,SNRNP40,SPPL3,FZR1,ZNF330,PHB1,ALYREF,RPL8,RPL12 |
| 5.359e-06 | -12.14 | SEC23IP (SEC23 interacting protein) | protein interactions | 11196 | 233 | 97 | 19454 | 5460 |
HSPA8,RAB5A,SLC31A1,MCMBP,PXMP2,PTAR1,BET1,RND2,TIMM13,CTBP1,EIF4B,TBC1D13,CSNK1A1,ARF1,LMBR1L,DLST,SEC61B,PHF21A,PRDX2,ACTB,PSMB6,ESR2,BTG3,RAB11A,PRMT6,LAMTOR1,BRCA1,POLD4,NTRK3,LSM14B,CYP2C9,TMT1A,THNSL1,RPAP3,RUVBL2,PCNA,VPS26B,HNRNPF,TRIM37,SAR1B,B3GNT2,EZH2,RAB4A,KLHL12,TSG101,GJA1,ARHGAP25,TRAPPC10,KRT8,G0S2,RAB1B,OSBP,ZNF593,CEP19,NUP35,RAB5C,IFT25,XPO1,RHOG,RPA3,SLC39A9,SYVN1,PPIH,RAB9A,DERL1,KDM1A,SNRNP27,CDC42,RPA2,SSR1,WWP1,FGFR1,UBE2M,CCNF,ZNF518B,RAB2A,TRIM32,SEC13,IGF2BP1,UBE2H,RAB1A,YIF1A,PSMA5,RAB3B,URM1,GPX7,SSU72,DSTN,CEBPG,SEC23A,RAC2,CAV1,SLC25A46,LAMP3,TPM3,TRAPPC2L,MAP4 |
| 5.382e-06 | -12.13 | BRMS1 (BRMS1 transcriptional repressor and anoikis regulator) | protein interactions | 25855 | 94 | 47 | 19454 | 5460 |
WTAP,METTL14,MXD1,RNF113A,EP300,HDAC5,FOS,TGIF2LX,HDAC3,AR,BRMS1,CEP70,SMARCE1,CUL3,HNF1B,CREBBP,DNAJB6,HSP90AA1,SPOP,ING2,SRC,NMI,LRIF1,RBBP4,KLK9,SAP30,ELF1,EEF1A1,ING1,ZNF704,MAX,HBP1,EZH2,TGIF2,PRPS1,RBBP7,CSNK2A1,HDAC6,PFDN5,NFKB1,UBE2D1,GATAD1,SIN3A,KLF9,DIRAS3,BRMS1L,HNRNPL |
| 5.416e-06 | -12.13 | chemical homeostasis | biological process | GO:0048878 | 914 | 330 | 18204 | 5365 |
CAV1,ATP6V1A,PAX6,SIN3A,FTL,AQP2,SAR1B,EDNRA,FKBP1B,SNAPIN,PNPLA8,TPT1,CMA1,KCTD17,NUS1,MIR33B,CIB2,IREB2,CAV3,CMKLR2,ORMDL1,MIR208A,KLHL3,PCK2,MLLT6,RTN4,SMAD2,MIR148A,NPTN,SLC38A3,AQP3,FXN,CIB3,ATP1A3,AQP4,RHBG,SLC39A9,AQP11,CCDC186,SELENON,ATP2C1,FABP4,PSEN1,MIR146A,FITM2,STOML2,ATP6V0B,CCL5,KCNB1,RMDN3,ABHD4,MIR185,UBE3A,BAX,MIR379,ATP1B3,MYC,LAMP2,IGF1R,IL6,BGLAP,ADIPOR2,FTH1,KCNJ2,CCL3,VPS33A,CNNM4,CA2,MIR132,LDLR,HTR2A,INPP5K,ATP6AP2,ERRFI1,DHPS,TRPC1,PRNP,TLCD1,GRM1,MT1X,ATP6V1D,MTCH2,RNASEK,SLC1A3,HPS6,ATP2B4,APOC4,NR1H2,CAV2,PCSK9,LACC1,FOSL2,CCR1,CRY1,PRKCB,BAD,NUCKS1,CYB561D2,SLC4A8,OAS1,ACACA,CYB5R4,XBP1,SLC30A7,PRCP,GRIA1,RGN,MIR320A,FRRS1,NDFIP1,ATP1B1,FIS1,TRIM24,PICALM,CARTPT,SOD1,SLC8A1,ATP1A2,CNR1,NCOA5,PLSCR3,MBD5,UCP2,CHP1,IL1A,MIR144,NPC1L1,BOK,CALR,SLC1A1,RHCE,TWNK,SESN3,HYAL2,GSTP1,ATP5F1B,BAK1,VDR,RHAG,TF,MT3,GPX1,MINAR2,RMI1,MIR182,P2RY4,GCLC,PPP3CA,ATP6V1G1,AKT1,FTHL17,ACO1,PRND,SLC31A1,SMAD4,DRD3,MT1E,MT1A,CLN8,AKR1C1,FGF23,CYP27B1,PNPLA4,ALPL,MAIP1,FABP5,APOC2,TMEM199,VEGFA,B2M,MIRLET7G,HEXB,SLC41A1,ADCK1,CHRNA7,PIK3R1,TSPO,CCDC47,CA12,TLCD2,PIK3R2,SESN2,SLC30A5,CCL1,PRKACB,ZNHIT1,OPRK1,ACOX1,LIPA,SV2B,SLC16A1,CYP7A1,TLCD3B,PPARG,STIM1,CCDC22,FUNDC2,FATE1,SFRP4,CACNB2,RRAGA,PIK3CA,SLC39A13,ARF1,ICAM1,CLIC4,SNX10,COMMD9,RHCG,GPIHBP1,NEO1,SURF4,MIR34A,LEPR,SLC39A7,SOD2,MIR15A,CYP39A1,EHD1,KCNJ11,EXT1,P2RY1,FGFR1,COMT,IL18,SLC25A46,ADORA1,CIAO3,NKIRAS1,CCL11,COX11,PSEN2,PTPN11,MIR590,SLC25A23,CCL8,TM9SF4,ATF4,TMEM165,LRRC8A,LEP,FASLG,CYB561,TLCD4,SLC4A10,TASL,NHERF1,NPPC,DISC1,SLC11A2,GLRX5,HSP90B1,PML,NKIRAS2,MT1M,TRA2B,BOLA1,CACNB4,MIR16-1,ANKH,GPR89A,CYP11B1,SRI,ADNP,LRRC8D,TMEM203,DMPK,CFTR,LAMTOR1,PLN,MYLIP,SLC12A2,BOLA3,GRM2,MT2A,TMEM97,SLC29A1,CCR2,BOLA2B,F2,VPS54,SFTPD,SLC25A27,CCL19,NPTX1,STC1,CYP11B2,SLC7A11,VAPB,ADIPOQ,CRTC2,RAF1,SLC39A10,KCNJ10,SMAD3,ATP6V0E1,ISCU,PPT1,GPAM,CYBRD1,DBH,ATP1A1,CLTRN,NPC2,SELENOK,TMEM106B,TFRC,COX19,ORMDL3,MBL2,CYP4F12,HFE,CXCL12,RAB11B,KCNMA1,CD40,TMBIM6,CCL23,AKR1B1,TMEM174,FOXA3,FBXW7,ABHD5,S100A8,SLC22A17,AGER,STK11,ADIPOR1,SELENOT,SMDT1 |
| 5.446e-06 | -12.12 | positive regulation of catalytic activity | biological process | GO:0043085 | 868 | 315 | 18204 | 5365 |
MEF2C,NUS1,PRKAG1,PMAIP1,LPAR2,HSP90AB1,AGAP2,NDUFA4,BCL2A1,SIPA1L1,TNKS,TAB1,DSTYK,EDNRA,GPR65,CAV1,MIR21,CD4,UBE2S,ARL6IP5,PSEN1,RPS27L,RPS2,FXN,UBE2I,LCP2,IFT57,IL4,RGCC,MCL1,HTRA2,RGS10,EMP2,FZR1,DAPK1,PPIA,CD86,GNAQ,CDC20,DUSP19,CCL17,MYC,ERP29,FERMT2,BAX,IGF1R,TOM1L1,SFRP1,MMUT,EPHA4,TLR3,TBC1D25,IL12B,EFNA3,MAGEC2,CCL5,ACVR1C,PRNP,MAP3K12,HSP90AA1,HTR2A,HSPD1,BCL10,SSBP1,TPD52L1,USP6NL,PDCD5,PPP1R12A,CCL3,PSRC1,BAD,FCGR1A,CRHR1,DVL2,MAP2K1,GSK3A,NR1H2,FGF1,PKIB,CAV2,PLA2G5,CCT2,BCL2L1,PIP5K1A,RASGRP2,JAK2,PTEN,MMD,SOD1,DIRAS2,CARTPT,DLG3,HSPE1,TOPORS,ARRDC3,CCND1,FIS1,SKP1,MSH6,PLAA,TGFBR2,S1PR4,FAS,KIT,ANP32B,ADRB3,ARHGAP25,CCL21,ODAM,LMO4,MET,MT3,CCL24,CYFIP2,CCND3,GH1,BAK1,TXN,VDR,PCNA,CTSK,TGFB2,MAP2K3,SNX18,TAX1BP3,BOK,IGF1,APH1A,DKC1,PDCD10,PARM1,RFC3,CCL20,PROX1,KHDC1,C9orf72,GREM1,ADRB2,TANK,TLR6,CCR7,AIFM1,TBC1D4,AKT1,DHX9,TNFSF15,IL1B,PKP4,RFC2,ITK,PRIM2,CHRNA7,EZH2,IL23A,RALGAPA2,NCSTN,RGS6,CYP27B1,PRELID1,RBCK1,IL34,FGF23,APOC2,AGAP1,COX17,PSME2,RGP1,CAP2,CAMK1,NBN,RXFP2,CXCL13,NTRK3,TCP1,IFI16,STIM1,NTRK2,PPARG,PRKCQ,RHOG,CCL1,CDKN1B,NEK7,SERINC1,LGR4,MIR15A,POR,CACUL1,ROCK1,ITGA6,GPIHBP1,CLEC7A,TCIM,TAB2,IFNG,CCNY,TNFSF10,LPAR1,TIAM1,RGS1,DIPK2A,CD200,HNRNPA2B1,THY1,PIK3CG,TLR4,FASLG,DLG4,LEP,KLF4,PSEN2,PLCB2,PHB2,CCL11,CCL8,PTPN1,SRC,ADRA1A,GHR,ADORA3,WRAP53,ANGPT1,PTGES3,FGFR1,TSHR,CHTOP,FAM162A,MIR26B,PSENEN,CCL4L1,TBC1D10C,DAP,STRADB,NLRP2,CCL18,TERT,CRADD,DRD1,PIH1D1,TMSB4X,MAPKAPK5,RFC4,CDKN1A,ZNF622,PSMD10,TBC1D13,SEMG2,CHI3L1,CCL2,PLSCR1,CTSD,XRCC5,TBC1D16,CLDN3,NHEJ1,P2RY11,CCL19,F2,DIRAS1,AZIN2,NLRP3,CCL25,TRAF6,TBC1D5,PSME1,NEK2,YWHAB,MIR17,TBC1D17,DDR1,TMIGD3,MID1IP1,PHB1,RPS3,EGLN3,HNRNPD,AVPR1B,UBE2L3,RFC5,TRAF2,RAP1A,ISCU,CX3CL1,RAF1,SMAD3,XCL1,MUL1,ROCK2,DDRGK1,MAP3K11,TBC1D1,TNF,ADIPOQ,ZC3H15,VSIR,AGER,STK11,PYCARD,HRAS,NKX3-1,FBXW7,CAB39,S100A10,S100A8,CLDN4,EPHA2,RALB,CCL23,CD40,MIR205,SYK,CORO1C,MAPRE2,HMGB1,NLRP1 |
| 5.456e-06 | -12.12 | EIF4A2 (eukaryotic translation initiation factor 4A2) | protein interactions | 1974 | 159 | 71 | 19454 | 5460 |
MCPH1,CMBL,EIF3K,EIF4A3,CCNF,OPTN,PSPC1,PRRC2A,APEX1,TUBB,EIF4A2,BAG3,RPS29,RUNX1,FBXO7,PDCD4,BRCA1,SPOP,EIF3G,HSPB2,HSPA8,CRY1,DDX39B,RPA3,BAP1,EIF4E,CFTR,NEK2,HECTD1,TRIM36,HEXIM1,EIF4B,RPA2,CD4,CETN2,CDC5L,PPIA,AKAP17A,TMPO,RBM42,SUMO2,PRNP,TOP1,RPS16,EIF3D,DDRGK1,TPM3,CD81,HNRNPA1,MDFI,HSPB1,DRG1,SSX2IP,MYO1B,PABPC1,EIF3E,PFDN1,TRIM37,EIF4EBP2,RPAP2,CD2BP2,RPSA,YTHDF2,TOP3B,OTULIN,PLD3,RNF8,NUPR1,RPS11,VAC14,CHMP4C |
| 5.471e-06 | -12.12 | FSCN1 (fascin actin-bundling protein 1) | protein interactions | 6624 | 236 | 98 | 19454 | 5460 |
DLST,ENO2,FBXO22,SNRNP40,PRDX2,GALE,RHEB,PRPF31,MYC,OXTR,SCFD1,DCAF4,RAB5A,PSMA3,RFC4,DET1,RPL27A,VAPB,ATP5PO,PAK2,EED,PSMB4,PPP2CB,PSMB5,PSME2,DNM2,SNX2,DNAJB9,CTNNB1,VPS26A,PRDX1,RPL23,COTL1,AK2,RHOG,ZYX,CBLL1,IMPA2,RPS27A,TRIM37,RBBP7,G3BP1,FAF2,GTPBP1,CHMP4C,NGB,EZH2,PTEN,SMAP2,PELP1,SEC63,TECR,SMURF1,PRKCE,NDN,RAB14,CIAO1,UBE2H,PML,PRPF4,SIRT7,RPA3,BAP1,CRYZ,HSPA5,UGP2,PIAS1,CFTR,ELP3,SF3A1,ATG16L1,PRKCA,PICALM,METTL14,MRPS34,RB1,TES,DSTN,UBE2N,ACTA2,AIFM1,CGAS,MIF,LRRC40,HDAC6,RPL24,ERO1A,SLC25A11,RAB1A,FKBP8,ARF4,TMEM33,HADH,IPO8,MTCH2,GNAI3,SRP72,ARPC3 |
| 5.472e-06 | -12.12 | endosome | cellular component | GO:0005768 | 1067 | 375 | 19108 | 5553 |
RAB1A,TRAPPC4,CTSK,SNAP25,VIPAS39,MYO1B,VAC14,MBL2,TLR8,AP3S2,PGA4,CD14,ANKRD50,PSENEN,ARRDC3,RAB22A,RAP2A,MYO6,RAB3C,TRAPPC1,TBC1D17,DENND6B,RAB23,CHMP1A,TBC1D16,FIG4,CMTM6,GPR15,TMEM59,HFE,VAMP3,EHBP1,PIP4P2,STMN2,CD63,CX3CR1,EXOC8,CD4,WDR83,CHID1,CHMP1B,ATP6V1A,TRAPPC14,SLC38A9,B2M,CRHBP,LEPROTL1,RNF128,TNF,CD1C,TNIK,SIAH2,LDLRAD4,MREG,CLVS2,AP5S1,TLR4,CHMP5,INPP4A,GPNMB,IL15RA,STX6,TRAPPC13,VPS33A,IFNAR1,UBB,ADRB1,IL15,MTMR2,ATP6V0B,VPS4B,TMBIM1,ACKR3,SQSTM1,ABHD17A,RAP2B,TF,RPS27A,TMEM106B,TAB2,BECN1,NME1,CORO1C,SNX3,LPAR1,RAB8B,PLEKHF1,TOLLIP,MAP2K1,TRAPPC10,TMEM127,CAV1,VAMP8,ATP6V0E1,UBE2D3,SLC11A2,CTSD,MARCHF3,VTA1,TNFAIP1,SERPINB1,LITAF,DKK1,RNF167,APOC2,LAPTM4A,GNPNAT1,AVL9,VPS4A,ARHGAP1,SCAMP5,CCR5,APH1A,VPS39,FCGR1A,STX12,HSPA8,LAMP3,MMD,TLR9,AP2M1,IRF7,RAB9A,CDIP1,FCMR,SPG21,RAB35,AVPR1B,DYNC1I1,CHMP2A,NTRK2,MCOLN1,ATP6AP2,NF2,OPTN,ATG9A,RAB5C,RAB27A,KCNH1,TRAK2,FLOT1,TLR3,TSG101,TMEM45B,TMEM165,CSH1,VPS26C,STX8,AP1AR,PLD3,CHMP2B,CD1A,ZMPSTE24,JAK2,SRC,SLA2,PLEKHJ1,LAMTOR1,TOM1,IL12A,TICAM1,FCHSD2,SLC1A1,CLIP3,AP2S1,CRHR1,ABCB9,SFTPC,TPT1,RAN,TAB1,PHETA2,SCYL2,SFTPD,TOM1L1,CXCR4,MAP1LC3A,TOM1L2,MME,C9orf72,RNASEK,AP2A1,AP1M1,SNX18,STARD3NL,NDFIP1,ATP6V1D,SNX12,SNX1,UBAP1,RAB4A,TRIM3,PTP4A2,CD1D,PIP4P1,TBC1D5,OCRL,CTSB,TSPAN15,CD1B,CFTR,CD1E,VPS28,HMGB1,RHOB,OCIAD2,CCDC22,NRP1,DIO3,USP8,DERL1,RAP1A,TUBA1A,CHMP4C,SNX10,STAMBP,TFRC,LRAT,ITM2B,EPHA4,AQP2,VTI1B,BOK,NCDN,EHD3,HSD17B6,SLC48A1,RAB40AL,TICAM2,PTPN1,SNX5,CD274,IL2RG,LDLR,WDR44,AP1S2,PICK1,PACSIN3,IL2RB,STAMBPL1,TRAF6,RAB3B,HDAC6,PDIA3,RAB33A,FGD2,GRIA1,BET1L,VAMP5,MTM1,RAB33B,TRIM27,HGS,SLC66A2,NCSTN,RAB5A,SNX20,CD164,GOSR2,VPS26B,AKT2,SFTPA1,LRP6,TUBG1,RNF11,EHD1,LAMP2,VPS26A,PHB1,RHOBTB1,GPC1,SLC31A1,ZNRF1,CDKN1B,UBXN6,DDIT3,OPRM1,NSG1,CLEC18A,PICALM,ABHD6,STX7,SNX14,CALY,TRAPPC3,RND2,LAMP5,GH1,ATP1A2,BST2,RAB14,AQP4,PSEN1,MMP14,LAMTOR3,BACE1,IRAK4,PML,AGAP2,TMUB1,SNX11,RAB3A,KCNJ11,RNF133,IL12B,RAB29,PSEN2,PCSK9,PLA2G4B,HAS3,ATG16L1,TLR7,LAMTOR2,RAB13,SCAMP2,CD2AP,CLCN6,TRAPPC2L,DNM2,JAK1,RAB31,VAMP7,ARF6,PLEKHF2,ARPC2,OR51E2,TMEM30A,ASTN1,RAB37,MYD88,VPS18,VPS16,HPS6,ABCC5,AP1G2,RNF148,CPTP,UBA52,TASL,RAB32,SLC6A4,HSPD1,RAB11B,ADRB2,PTP4A3,PDLIM4,LY96,EHD4,RHOU,PRDX3,RAB9B,FURIN,RAB3D,SNX17,DERL2,YKT6,TRAPPC6B,MRC1,TM9SF4,RAP2C,TMEM108,CLVS1,REP15,PARM1,ACAP2,PRL,SNX2,GRAP2,SYNDIG1,PLA2G5,FOLR1,MLC1,RAB11A,NIPA2,AP5M1 |
| 5.477e-06 | -12.11 | JUN (Jun proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 3725 | 452 | 170 | 19454 | 5460 |
VRK1,KPNA2,SEM1,SNRPG,RIGI,EGR1,MEPCE,PSMB10,NKRF,TMED1,NAE1,DHX9,NFE2L2,TAF2,PPP4C,BATF,SNAPC5,TP53,MTA3,MLLT6,TSC22D3,TOP1,MIF,FZR1,SURF6,MDM2,GTF2B,SMAD3,RB1,CEBPG,BECN1,CRBN,SMAD4,TAF9,PLEKHO1,NFKB1,ENY2,TPM3,COPS5,CSNK2A1,NR2F6,OIP5,FBXW7,HDAC3,BCL6,PIAS1,MBD3,MEF2A,PML,RPA3,SQSTM1,SPCS2,MTDH,ELOF1,LSM2,RPA2,STAT6,SUMO1,CCND1,EDF1,COMMD3,CEBPE,BUB3,VIRMA,UBA3,JUNB,UBB,LIG3,FBLN5,UBN1,CREB1,PSPC1,PELP1,CFAP298,UBE2I,COA5,CYTH1,RNF187,MAPRE1,POU1F1,SMAD2,NCKIPSD,ATF4,CSK,CREB3,AR,ATP5F1A,RUNX1,ASF1A,SATB1,AHCYL1,SSRP1,ATF3,TRIP4,MRFAP1L1,EWSR1,FAM76B,PICK1,BTG1,SMARCB1,MAX,VDR,TOP3B,GTF2E2,NFE2L1,MAPK10,TRAF2,SOX2,JUN,SUMO3,ASIC1,SUMO2,EGLN3,RPRD1A,WDR6,COPS2,RPLP2,TSG101,FOSL2,IKBKB,PPP3CA,MED4,HMGA1,IFI16,EXOC1,INSYN1,YWHAH,PHB2,NUDT2,HTR1A,SNRK,FOS,HIRA,SMARCD3,PTRHD1,DDIT3,CFDP1,EP300,HSPA8,PDP2,CTBP1,PPARG,NUFIP2,CEND1,NUP62,MAPKAPK5,CDKN1A,DET1,STAT1,IP6K1,APEX1,PRRC2A,NFKBIA,PHF21A,GTF2F2,GTF2F1,LMNB1,BRCA1,PSKH1,COP1,SP1,NTRK3,HSP90AA1,HNRNPC,CREBBP,MYC,NFYA,ATF1,SNRPB,SMARCE1 |
| 5.616e-06 | -12.09 | PRDX2 (peroxiredoxin 2) | protein interactions | 7001 | 286 | 115 | 19454 | 5460 |
BAX,COP1,CCT2,RHOB,YWHAZ,BTF3,ACO2,MYC,CUL3,PMPCA,CUL2,ESR2,CLIC4,PRDX2,RBBP4,TENT5C,SMU1,BAD,PIH1D1,PPT1,PRDX3,LAP3,WDR77,UFL1,HSPA8,SAT1,YAF2,RTL9,DDX39B,ARMC8,AGR2,DDRGK1,SYNJ2BP,PRDX1,CACYBP,EGLN3,ANKRA2,CCT7,TCP1,MPP1,ATP6V1A,GATD3,FOLR1,PHB1,EZH2,NGB,CHMP4C,SOX2,TUBA1A,PPP2R1A,B3GNT2,SAR1B,RBBP7,EWSR1,CCT8,UBE2H,FXN,GLOD4,LGALS8,ANAPC15,UBB,VIRMA,UBA3,LDHA,NDN,COPE,TXN,PDCL,HEXIM1,UBE2M,GSTP1,HECTD1,WTAP,RPA2,JUP,CDK1,METTL14,NEK2,CFTR,ATG16L1,SPR,CRYZ,HSPA5,RPL4,GPX4,PRDX6,SOD1,RPA3,BAP1,DVL2,RETREG2,HDAC6,COPS5,GAPDH,PGAM1,CDK9,CAND1,PRNP,RAC2,CD274,RPL12,SLC25A20,RNF8,TFCP2,ACTR2,HADH,GLRX5,URM1,TP53,CCT5,PSEN1,PRDX4,MSH6,HSD17B10,HINT1 |
| 5.619e-06 | -12.09 | AMOTL2 (angiomotin like 2) | protein interactions | 51421 | 148 | 67 | 19454 | 5460 |
DDIT3,LIN7C,CCND3,NFIL3,NF2,FXR2,LMO4,LMO3,MTMR6,NUP62,MFAP1,CDR2,WWP1,RNF146,SNRPD2,TRIM27,CINP,CHCHD3,VIRMA,ESR2,APEX1,MAGOHB,DYNLL1,YES1,NTAQ1,SMARCE1,FBXO7,RNF40,GSTM5,MYC,CCHCR1,GCC1,SPOP,TRAPPC14,GNG5,ERP29,FAM168A,TCEA2,TNKS2,RNF20,ZBTB16,ZBED1,SOX2,TRAF2,PPP2R1A,E2F4,RNF8,PSMC3,EZH2,MAGEA4,TRAPPC10,TNKS,TRAPPC3,EIF4E2,CYTH4,PRPF18,TMCC2,BRMS1L,MPP1,GNG11,YWHAH,YWHAG,XPO1,WWP2,NDC80,YWHAB,SPP1 |
| 5.639e-06 | -12.09 | SRSF9 (serine and arginine rich splicing factor 9) | protein interactions | 8683 | 213 | 90 | 19454 | 5460 |
MATR3,ESR2,APEX1,TNPO3,GTF2F1,MYC,CUL3,RNF40,MCM3,SNRPB,UFL1,TRA2B,SRSF2,MCMBP,EEF1G,SNRPA,NKAPD1,EP300,EIF4B,PABPC5,DYNC1I2,SRSF10,SRSF1,EED,MRPL18,MRPS26,RB1CC1,MAGOH,HMGA1,HNRNPA1,DDRGK1,TRA2A,HNRNPF,G3BP1,H1-6,UNC119B,HNRNPDL,SSRP1,HNRNPA2B1,PABPC1,EWSR1,UBE3A,SRSF7,EZH2,CHMP4C,ITGB5,RAF1,TOP3B,SOX2,NUP37,SRPK2,CCNF,EIF4A3,PSMC5,MACROH2A1,RC3H2,PAIP2,NRP1,UBE2H,AR,GTF2I,FBXW7,LMNA,GRM2,HSP90B1,METTL14,PRKCA,SF3A1,CFTR,CAND1,RPS16,FZR1,THOC1,PRNP,TOP1,CDK9,RBM42,CDC5L,EEF1B2,RCHY1,SNRNP70,CHCHD1,BRD3,GRSF1,MDC1,RIGI,SNIP1,GINS4,GFM2,NUPR1 |
| 5.659e-06 | -12.08 | MFAP1 (microfibril associated protein 1) | protein interactions | 4236 | 289 | 116 | 19454 | 5460 |
HSPB1,DDX23,NGDN,GAS8,YWHAG,DNTTIP1,XPO1,FRA10AC1,NDC80,HYPK,WDR82,HOMER3,CEP57L1,TMEM14B,TRAF2,SOX2,E2F4,DHX38,RAF1,PAX6,CDCA7L,ZBTB14,G3BP1,KRAS,RPS24,EWSR1,FAM76B,RPL31,HTRA2,RIT1,SNRPB,PSMD1,MRPL16,STAC3,MYC,SNRPB2,APEX1,TNPO3,ESR2,PSMD4,SMU1,AP2M1,TACO1,PIH1D1,NUFIP2,ZNF428,GKAP1,H1-5,COIL,PSENEN,FXR2,TRA2B,UFL1,ZFP64,EP300,NUP50,SF3B1,SNRPA,BRD3,SSX2IP,CSNK2A1,PPIL4,RBM17,RBM42,CDK9,EIF2B2,TOP1,THOC1,PLEKHF2,TAF2,NUPR1,ZFP1,IK,CBX3,CDK8,DDX42,THAP1,CD2BP2,YIPF4,CENPM,TBK1,MRPL22,STX11,MEPCE,CDC40,TSSC4,SNIP1,UBE2H,PEA15,BICD2,MECP2,SPOP,CEP70,DNAJC8,GPRASP3,DYRK1A,SRPK2,PPP1R10,TRIM54,TRIM24,CTTN,EIF4A3,ZNF330,PSPC1,CCNF,TFIP11,ZNF574,TOX4,RPA2,LMNA,CDK1,SF3A1,LDOC1,RNF113A,PGK1,RPA3 |
| 5.671e-06 | -12.08 | IMMP2L (inner mitochondrial membrane peptidase subunit 2) | protein interactions | 83943 | 382 | 147 | 19454 | 5460 |
ILK,CBR3,MRPS25,NOA1,UFD1,PYCR1,COPS7A,PARL,KBTBD6,NDUFAF4,CHCHD3,TIMM21,DLST,TACO1,NDUFA5,FDFT1,PIH1D1,VPS18,NDUFAF3,TIMM13,PRDX3,MTX2,NUP62,SELENOO,MRPS7,NT5C3A,NDUFS2,EXD2,ATPAF2,DICER1,ARMC8,HNRNPD,MRPS26,AK2,NDUFV2,MRPS35,PIK3R1,CLPX,NDUFS8,PEG10,GSTCD,HNRNPL,POLR2L,POLR2C,NDUFA12,NDUFS6,PRKAG1,NUDT19,CA14,NUP37,FAF2,ATP5F1D,ETFA,KGD4,RRAGB,USP30,MRPS11,VPS26B,HINT2,RPAP3,OPA3,HSPD1,PREPL,DNAJC19,CALU,CISD1,MRPS16,PYCR2,NDUFAF2,SUCLG2,SLC25A4,PTPMT1,GUCY1B1,PSPC1,HECTD1,CYC1,PRKCA,SAMM50,MRPS34,QRSL1,MRPL10,POLR1D,MYL12B,TIMMDC1,COQ8B,PCK2,POLDIP2,GRPEL1,TOMM20,MRPL41,MRPL40,MRPL17,NME4,TMEM126B,GFM1,TWNK,IDH3A,AGPAT1,HDAC6,CSNK2A1,COX5A,GRSF1,RNF14,CALR,SLC25A12,MRPS23,MRPL24,TOMM70,MRPL50,IFRD2,RPL35A,COX4I1,METAP1,SSBP1,AIFM1,MRPS9,SDHB,GEMIN7,CAPN2,PPP4C,NDUFS3,ACADSB,EXOC3,CHAMP1,BCS1L,ZMYM4,PPIF,MTARC2,MAP2K3,GLRX5,NDUFA2,MRPL47,RAP1A,TBK1,RRM1,ATP5PB,VPS16,ABHD10,MRPS18C,FASTKD5,HSPE1,NEDD8,CAMK2G,PDE12,TMX3,CLPB,PPP1R12A |
| 5.671e-06 | -12.08 | COPA (COPI coat complex subunit alpha) | protein interactions | 1314 | 382 | 147 | 19454 | 5460 |
WBP2,HSPA8,SF3B1,NUP50,EP300,BET1L,UFL1,EMC1,STAU1,MTF1,EDEM3,VAPB,ARCN1,CSNK1A1,PIH1D1,LMBR1L,CYB5R3,ANAPC2,SEC61B,MATR3,RPL10,ESR2,TMED5,MYC,DSN1,TMEM38B,HNRNPC,CUL3,ATG101,MCM4,BRCA1,NTRK3,SCFD1,RIT1,EMC8,KRAS,TNF,G3BP1,TRIM37,RPS27A,MCM6,SACM1L,B3GNT2,ARFGAP1,RAF1,DHX38,ISG15,SOX2,RPN1,EZH2,STIM1,PDHA1,CHMP4C,POLR2C,RNF126,PHB1,GJA1,SUMO2,TCP1,EGLN3,ERLIN1,TMEM237,PIK3R1,UBXN6,IFI16,XPO1,WDR11,DDRGK1,CTNNB1,AGR2,POU5F1,BAP1,APMAP,SOD1,PPM1G,RPA3,SIRT7,DERL1,RTN4,FBXW7,PIAS1,HSPA5,ATG16L1,CDC42,GABRA1,CFTR,RPA2,FGFR1,METTL14,GRM2,UBE2M,HEXIM1,HECTD1,CCNF,ATL1,PSMA6,FAM210A,COPZ2,GANAB,PTEN,COPE,TECR,VIRMA,AKT3,VAMP5,DEPDC1B,RUNX1,USP14,RACGAP1,TXNIP,ATP1A1,UBE2H,MAP1B,NSDHL,STX8,SLC25A11,EMC2,FBXO25,RIGI,FKBP8,PRDX4,SMN1,FBP1,INSIG2,NUPR1,PTPN1,CD274,HSD17B11,SEC23A,TES,FZR1,TMPO,LMAN1,ILVBL,ZBTB2,CDC5L,CALR,MOV10,FAM20C,DHRS7,HDAC6,GOLPH3L,KCNJ10,SNRNP70,ESYT1,STYK1,FGR |
| 5.686e-06 | -12.08 | STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B) | protein interactions | 201595 | 242 | 100 | 19454 | 5460 |
RAB11A,OST4,NTRK3,LMNB1,FAS,SEC61B,RMDN3,LMBR1L,EDEM3,SEC62,OTULINL,RND2,BET1,PGRMC1,RNF10,HADHA,EP300,AKAP1,PMAIP1,TMEM106B,DNAJC3,DNAJC22,STX7,PXMP2,STAU1,EEF1G,HSCB,EMC1,DDRGK1,RAB5C,LAMP2,RB1CC1,RHOG,CORO1C,FBXO32,RHOH,DNAJB9,DNAJC25,SOX2,RAB4A,PTRH2,RPN1,STIM1,SRSF7,TMT1A,CYP2C9,RPL31,KRAS,EMC8,TIA1,RAB2A,CALU,DNAJC10,SPOP,SEC63,VIRMA,RHOJ,CTSB,ST7,PLP2,CDC42,SSR1,GRM2,PICALM,HSP90B1,RPA2,LMNA,DERL1,RAB9A,RPA3,HSPA5,PIAS1,DAD1,FBXW7,RPS15,COPS5,LAMP3,EDEM1,SLC25A46,DPP4,ESYT1,POR,RAC2,HSD17B11,MYBL2,SYNCRIP,STT3A,PTPN1,TMPO,LMAN1,ARF6,DNAJC1,TP53,CCDC47,EMC2,FKBP8,TUSC3,BACH1,DNAJC30,RAB3B |
| 5.757e-06 | -12.07 | MYO6 (myosin VI) | protein interactions | 4646 | 373 | 144 | 19454 | 5460 |
RND3,RHOBTB1,SNRPE,RNF126,AP2S1,IRF8,PTRH2,PDHA1,ISG15,TOP3B,RAF1,RPS27A,PCGF3,G3BP1,TNF,PSMA1,SEMA4C,TRIM37,ANKRD50,HNRNPA1,LAMP2,SRSF10,EGLN3,HNRNPL,RHOH,GJA1,RPRD1A,PAK2,PPP1CB,RND2,TOM1L2,STX7,RNF11,FBXO30,UFL1,TRA2B,STAU1,NSFL1C,TXNL1,RAB5A,DDX39B,FOS,WBP2,NTRK3,SP1,DNAJB6,LAMTOR1,RHOB,FTSJ3,MYO6,BTF3,GGH,MYC,CUL3,HNRNPC,PPP1R3C,ESR2,APEX1,STAT1,FBXO22,TAX1BP1,AP2M1,CPSF1,LMBR1L,DLST,NUPR1,FURIN,RAD23B,TFRC,TFCP2,ACTR2,CAPZA2,DNAJC2,RPAP2,KBTBD4,FBP1,IPO8,TP53,FBXO25,SMN1,CAPZA1,TOLLIP,TOM1,ABCE1,NTRK2,HSD17B10,DLG1,FBXO34,TMOD2,SLC2A1,SNRNP70,HDAC6,COPS5,MOV10,DPP4,ZNF24,DBT,STX6,TMPO,G6PD,SURF6,CAV1,ARF6,FCHO2,RAC2,RPA2,JUP,RPRD1B,PICALM,SIPA1L1,CD2AP,CDC42,PRMT2,CFTR,SYNRG,MYL12B,HSPA5,RAB9A,SQSTM1,RPA3,BAP1,RHOU,PML,AP2A1,UBE2H,GEMIN8,H2BC9,DNAJC5,USP14,PPP1CC,TUFM,AR,CSTF3,SH3BGRL,SH3BP4,VIRMA,CTSB,DAPK1,MOB4,CCNF,OPTN,CCSER2,ENO1,CTTN |
| 5.770e-06 | -12.06 | RND2 (Rho family GTPase 2) | protein interactions | 8153 | 437 | 165 | 19454 | 5460 |
RAB32,PIK3R1,WWP2,PTDSS1,OLR1,PPFIBP1,CTNNB1,DDRGK1,WDR11,ARHGAP5,VPS4A,WDR6,PHB1,GJA1,STX5,SPTAN1,VAMP7,PPIA,CACYBP,ERLIN1,RAB11B,STBD1,MACO1,CSNK1E,FAF2,IFNGR1,STIM1,RPN1,PCDH17,PTRH2,TMEM87A,TOP2B,SLC39A7,JAK1,CDK5,EFNB1,SLC20A2,PSMD12,MCM6,SSRP1,FLOT1,GOLGA7,PKP4,MRPL16,TOMM40,PSMD1,MLF2,STX16,LAMTOR1,LMNB1,MYO6,SCFD1,SLC7A11,SLC38A1,FAM91A1,RRAS2,FAM83B,LRRC1,CHCHD3,ATP6AP2,USP6NL,GOSR2,NOTCH2,ETF1,VAPB,DDX39B,CXCR4,EXD2,TXNL1,EMC1,TRA2B,ATAD1,NSFL1C,GNB4,STX7,ITGAV,RELL1,TMEM199,SLITRK5,SLC2A1,POR,NOS1AP,ESYT1,KPNA1,OSBPL8,STT3A,PTPN1,SRPRA,H2AZ1,EHBP1,FLRT2,SLC39A10,ARL6IP5,TOP1,LMAN1,DBT,STX6,SLC38A2,TMPO,CAV1,CMPK1,CCDC47,LBR,TFRC,BMPR2,CASK,RAB1A,NSDHL,DLG1,SLC25A11,SFXN1,SLC16A1,ABCE1,SNAP23,EMC2,NEDD8,CSE1L,SRPRB,CTNND1,SLC6A8,FKBP8,RAB2A,RPF2,SLC25A1,DEPDC1B,RACGAP1,GORASP2,CISD1,EPHA2,XPOT,ATP1A1,VAMP3,UQCRC2,NECTIN2,GANAB,RPS12,MACROH2A1,STX10,YES1,SH3BP4,GNAI2,SPTBN1,RABL3,SEC22B,ARHGAP1,SNRPN,JUP,GOLGA5,STOM,SSR1,SLC12A2,MEST,LEMD3,CSNK1G3,TEX264,ITM2B,LRP10,MTDH,RAB9A,MAVS,YKT6,FTSJ1,PIK3R2,TMEM209,BRIX1 |
| 5.799e-06 | -12.06 | FCER1G (Fc epsilon receptor Ig) | protein interactions | 2207 | 89 | 45 | 19454 | 5460 |
COX20,FA2H,FUNDC2,CNIH1,TSPO2,TMEM19,SLC38A7,TSPO,SYNJ2BP,TMEM107,FXYD6,ADGRE2,PDZK1IP1,C2CD2L,SFXN1,RUSF1,YIF1A,SLC35G2,UNC50,SLC7A14,RIGI,LEPROTL1,NRM,UBIAD1,YIPF4,TMEM31,TMEM14B,NCR3,STX12,CDIPT,SLC1A1,THBD,USP5,USP13,FAXDC2,TMEM179B,SLC39A9,SLC7A1,SEC22B,SYK,VAMP1,PLP2,SYS1,LMNA,FCAR |
| 5.799e-06 | -12.06 | FOXO3 (forkhead box O3) | protein interactions | 2309 | 89 | 45 | 19454 | 5460 |
TERT,EP300,PGK1,PCNA,S100B,CDKN1A,SMAD1,PPP2R1A,H2AX,TP53,TOP3B,VDR,CTBP1,RPA2,LDLR,CDK6,RB1,PPP2CB,SMAD3,VIRMA,ESR2,EGLN3,MDM2,NR1H2,HNRNPL,STK4,CTNNB1,YWHAG,XPO1,ATG101,YWHAH,SFN,CREBBP,MYC,TAF5L,AKT1,YWHAB,CDKN1B,SMAD2,YWHAZ,BRCA1,FKBP4,BICD2,SMAD4,IKBKB |
| 5.799e-06 | -12.06 | positive regulation of biosynthetic process | biological process | GO:0009891 | 2697 | 892 | 18204 | 5365 |
CDK5RAP3,RGMA,ATF1,E4F1,TAF11,FGF1,NR1H2,MIR125A,IL2,MIR130A,CYTL1,HNRNPAB,AR,SOD1,XBP1,MET,PID1,KIT,RBBP4,MAX,VDR,NEUROD6,TEF,CREB3L4,MT3,TOX,DKC1,HMX2,NFKBIA,IGF1,ENY2,TCF23,MIR675,SIRT7,CALR,RPS4X,AGR2,FUBP3,TLR6,CCT7,RPL26,ITGA2,SERTAD2,MIR182,ELAVL4,CEBPE,SLC45A3,PPP3CA,WNT7A,VSTM2A,DYRK1B,AKT1,TGFB3,IL1B,UCN,GABPB1,CD80,TP53INP2,MED27,PRKAG1,GTF2A1,SSBP3,MAD2L2,SMYD3,PAX6,RIGI,CLEC6A,WNT10B,MEF2B,CDC73,ZNF507,MIR96,DNAJC3,SMARCD3,TLR9,PLCB1,ADM2,HDAC3,MLLT6,ZBTB16,ZNF24,TRAF3IP2,TP53INP1,ID4,AGPAT1,EFCAB7,IL6,PAIP1,CD86,PADI2,SOX21,MIR223,ZNF513,ELF1,FCER1G,DDX1,MMP14,HAX1,E2F4,SF3B4,SMARCE1,TENT4A,ACTL6A,PPP1R12A,AKT2,CD274,FOXP3,UHMK1,SERTAD3,PIH1D1,MIR16-1,RDH10,IGF2BP1,MAP2K6,CLEC9A,CHCHD2,CCL2,PSMC5,POU1F1,NUP62,ARL2BP,MAPKAPK5,PDE2A,WBP2,PIAS1,VAMP3,RNF10,AKAP8L,XRCC5,TBK1,CYRIB,STAT5A,VIP,APOBEC3A,MRPL12,MIR183,TLR2,CYP1B1,ZNF287,UBE2L3,TRMT112,TRIM32,MED9,SERTAD1,LAMP3,PRKAB1,MED23,STAR,BIRC2,YES1,SPTBN1,NIF3L1,CD2,VSIR,TCEA1,MIR101-1,NME2,FOXA3,PRDX6,SGF29,TESC,NOG,EAF2,ALKBH4,APOBEC3C,CREB3,STK11,MED22,TRIM5,FGF16,PITHD1,SYK,HILPDA,NR1I3,NLRP1,ACVR1B,MED10,CD40,BOLL,MTA2,IL23A,VEGFA,SLC38A2,CCAR1,TLR1,IL15,MIR769,FGF23,EIF3E,MTPN,BCL9,ELK4,DEK,SOX14,TCP1,CAPN2,FZD4,NIBAN2,TRUB1,CAMK1,PIK3R1,NR2E1,PIK3R2,SETD4,KLF1,CCL1,OSM,ROCK1,SUPT4H1,ETV6,TAF10,IL17F,APEX1,CD58,PIK3CG,PDE4B,TFEB,MIR140,CD40LG,IL18,ELK3,UQCC2,WRAP53,IRF8,PRMT2,HGS,HDAC5,MAP2K1,MIR511,NUCKS1,ANKRD49,IL5,EDF1,RGMB,ZBED1,TLR7,CDC5L,PRPF19,NR1I2,KDM1A,TOPORS,HBB,DNAJB9,RBM23,CNOT6,SF3B5,PAEP,HOXC4,HNRNPA0,SUB1,RGN,SOX9,STAT2,LTB,PAOX,RERE,TLE1,SCAND1,TRIM8,RPRD1B,PARM1,MAP2K3,LRP3,UAP1,CCR7,STAT6,ISG15,MBD3,HAND2,PRDM4,ADRB2,ZNF345,HCFC2,MSL2,RFC2,DHX9,DKK1,SPP1,HOXB1,TADA1,RUVBL2,ING2,GPBP1L1,TYROBP,MAVS,ZBTB17,KANSL3,MIR149,CD46,FAM98A,ARPP19,NLRP9,CD81,NKRF,DGCR8,MIR146A,MDC1,HSPA5,IL20RB,MYD88,TAF5L,ILF2,IL4,SFRP1,IGF1R,RTRAF,AGO1,NUPR1,RORB,CCL5,DYRK2,AKAP12,DEFB124,MOSPD1,TLR3,PELP1,GTF2F2,IL6ST,CSF2,RFX4,BARX2,MAP3K12,HEY2,IRF3,SETD7,KLF12,YWHAH,HNF1B,CCL3,MIF,IL12A,BCL10,MIR132,LILRB1,EIF5A2,ILK,TAFAZZIN,NLRP2,RB1,CITED1,TENT5C,SUPT5H,NFYA,MED4,NDN,CDK9,TMSB4X,CLDN3,IRF4,FOXC2,AIF1,NEUROG2,ZBED4,GJA1,MIR17,NLRP3,CEBPG,CNTN1,AVPR1B,FCGR2A,MID1IP1,RUVBL1,ING1,PHB1,ACTB,HMGA1,FGF3,TNF,NGRN,CX3CL1,RBPJ,SF3B1,XCL1,MED11,EMILIN1,ITGB8,HINFP,CCT8,LURAP1,IL1RAP,MZB1,GTF2A2,FGF7,TOP2B,DDAH1,HFE,PLAC8,SH3BGRL,B2M,PRIM2,LHX2,GTF2I,HEXB,DROSHA,KPNA2,HMCES,C1QTNF1,LUM,ZNF668,TRIM44,TRIM15,APOC2,RBM3,MIR212,EPCAM,TRA2A,PLGRKT,TRIM52,FOXJ3,RHOG,SOST,NCBP2,SOD2,NEK7,ACTL6B,MDM2,TP53,ZBED3,KLF4,PAX9,JADE1,ARF4,TLR4,MIR99B,ZNF574,TRIP4,ZNF473,BAG2,HSPA8,CSRNP3,RAP2C,KPNA6,LACC1,DVL2,RAMP3,GSK3A,CRY1,RAB27A,CD34,MORF4L1,MED31,LMO2,JAK2,PKIB,STAT1,CAND1,TIRAP,LRP6,CDK12,SS18,PSMC3,RRN3,TRIM24,MSN,CREBZF,TNFSF13,AATF,LMO4,ODAM,GRIA1,MLLT11,MIR206,CD14,EIF2AK2,RLN2,CTNNB1,SHLD1,HYAL2,BACH1,TMEM106A,GPT,KLK5,EP300,SNX5,RFC3,PDCD10,WDR77,PIK3R3,NAA16,EIF3D,KARS1,PRMT5,INO80E,TANK,SMAD4,AMELX,LMNA,UBE2V1,POLR3F,CD36,RBBP9,MIR33B,TCF21,POU5F1,IREB2,FOXD3,RMND1,LYAR,ELK1,MED29,LILRA2,MIR30B,MIR21,ECD,DNM2,MIR548C,SYNCRIP,MYBL2,CREBL2,RGCC,ERP29,RFX5,ABHD6,RSAD2,GTF2F1,ZFP64,MIR107,ZNF267,THRAP3,FOXP1,STOML2,FGR,LDB2,POLR3B,RNASEL,DUOXA2,UBE3A,IL12B,RNF14,MTA3,NEUROD2,ZNF263,IFNGR1,RXRG,FLOT1,PPARA,PELI1,CXXC1,PRL,JUNB,OTX2,HAS3,JUN,PNP,HSPD1,ENO1,LDLR,DMAP1,TERT,NFKB1,PABPC1,SUPT3H,PLP1,HLF,IRF2BPL,TFCP2,BMPR1B,CHI3L1,HCLS1,FOS,TLR5,CCL19,RNF40,PLAGL1,CD38,NEK2,TRAF6,FXR2,TICAM2,NDP,TUSC2,TAF9,WNT2,HNRNPD,EIF4A3,KMT5B,TRIM62,SELENOK,TFRC,PCBD1,SMAD3,CRTC2,MIR24-1,CSRNP1,ATF3,NKX3-1,RPS7,FCGR2B,PKNOX1,STAP1,CLU,MIR205,MED30,KLF10,BMPR2,SEMA7A,TFE3,MIR29A,EXOSC3,SMAD9,MPV17L2,NFE2L2,TICAM1,SOX3,BMPR1A,MECP2,SMARCB1,TLR8,IFI16,NTRK3,ZNF319,DDAH2,CCDC3,LMO3,CCT5,NTRK2,STARD4,RFXANK,METTL14,ACTR2,EIF2B5,IRF1,PQBP1,UTP15,AFAP1L2,STK16,MEF2A,IFNG,MED17,PHB2,ZNF175,ATF4,CD200,TRIM21,LEP,HNRNPK,SQSTM1,POLR2G,PTGES3,NRDE2,SRC,ANGPT1,ZNF609,SMARCA5,PAGR1,LTA,FOSL2,SHC1,PRKCB,CTBP1,COPS5,TRAF3IP3,SETD3,OAS1,HNRNPC,SMAD1,CCT2,IRF7,ACTN4,RIT2,MACROH2A1,PICALM,LITAF,MAFG,CDK7,PYM1,TRIM22,CIRBP,NFE2,TADA3,CCL21,MTF1,BAZ1B,AIP,FGF10,PCNA,ZBTB38,TF,NCK1,IL2RG,IRF6,RASL11A,SVIP,SRPK2,KRAS,NOTCH2,DPY30,ACTA2,IL1A,CHP1,TGFB2,MIR144,PIWIL2,CDH13,KLK3,CREBBP,PROX1,ADTRP,MTDH,ZBTB18,GREM1,IRF2,TRIM37,NFKBIB,WASL,SOX2,PTPN22,PXYLP1,ABHD14B,DYRK1A,PIM2,RAB1A,CD28,CBFB,HSP90AB1,MEF2C,MSTN,SUPT7L,MEPCE,IFNB1,CAV1,TNKS,MEAF6,ZGLP1,APOBEC3F,MIR324,SNRNP70,CD4,RPS27L,TNKS2,PSEN1,EGR2,IFIH1,RBM22,IRF9,ZMPSTE24,RUNX1,SMAD2,TAF2,BUD31,SLC38A3,BRCA1,MYC,FRMD8,CREB1,MARS1,HSPB1,CASK,G3BP1,GPSM3,SPON1,SSBP2,HNRNPA1,DLX1,WWP2,SMAD5,NFIL3,HSP90AA1,MED21,TNFSF8,SASH3,PDCD5,PSRC1,CD83,INPP5K,DDT,HTR2A,RPS6KA4,OSR2,CDK1,APLN,ATP6AP2,TRA2B,FBXW11,CGAS,OGG1,CXCL10,TNFRSF14,ZNF593,RFC4,SPHK2,USP16,POMT2,CCR2,F2,PLSCR1,MIR657,TFDP2,BRD3,LDB1,ACVR1,RFC5,NMBR,MIR145,TRAF2,MSX1,TRIM6,LY96,RPS3,EEF2,DDRGK1,RBBP7,NAA15,FGF17,LBH,POLDIP3,ADIPOQ,CRLF3,RAF1,ARMCX3,PTGFR,IL10,ROCK2,MIR640,H2AZ1,YAF2,LARP4B,GABPA,S100A10,HRAS,PYCARD,MIR23A,ZNF304,AGER,BATF,YTHDF1,HMGB1,INO80C,ZNF770,SSBP4,ESR2,YTHDF2,NFYB,NCSTN,EZH1,RFXAP,IL7,ITK,UPF3B,IER2,RAD21,NR4A2,EPO,SLC6A4,IKBKB,MYRF,IL34,TGFB1I1,EGR1,GAPDH,CNOT7,SP1,CYP7A1,PPARG,PTGER4,CCNA2,RPL23,SFRP4,RNF20,MIR106A,RNF187,PRKCQ,JUP,ZNHIT1,PGR,VPS72,MITF,ITGA6,IL21,CLEC7A,MIR34A,UBP1,IL13,TAF7,CXCL8,IDO1,TENT5D,TOMM70,PTPN11,TFPT,DNAJC2,CDK6,DDIT3,TRIM27,SRSF1,P2RY1,HELT,ACSS2,FGF22,SIX5,SCAMP5,VGLL2 |
| 5.829e-06 | -12.05 | UCH proteinases | REACTOME pathways | R-HSA-5689603 | 105 | 55 | 10285 | 3229 |
PSMB7,PSMD3,PSMB1,ACTL6A,BAP1,H2AC1,PSMB5,PSMA3,ACTB,PSMC4,SENP8,UCHL3,PSMA4,PSMB10,PSMA5,PSMB11,PSMC5,PSMB6,PSMA2,H2AC25,PSMB3,USP15,PSMD10,PSME1,PSMD7,INO80E,PSMD14,MBD5,UBA52,TGFBR2,UBB,H2AC7,RUVBL1,PSMC1,PSMD12,NEDD8,H2AC13,ADRM1,PSMD1,PSMB2,INO80C,PSMA6,PSME2,PSMB4,PSMD6,SEM1,PSMB9,H2AC4,H2AC14,PSMC3,PSMA1,H2AC6,RPS27A,TFPT,PSMD4 |
| 5.936e-06 | -12.03 | Cell Cycle Checkpoints | REACTOME pathways | R-HSA-69620 | 201 | 93 | 10285 | 3229 |
PSMD14,CDC26,UBB,PSME1,CDK1,PSMD7,H2BC12,H2BC17,MCM4,PSMA4,PSMB10,PSMC5,SFN,PSMB11,BUB3,PSMB6,MCM6,PSMA2,RNF8,H2BC11,RPA2,PSMB7,CDC16,PSMD3,PSMB1,CDC20,RMI1,PSMB5,PSMA3,ORC5,PSMC4,CDKN1B,H2BC1,H2BC9,RFC4,CCNA2,PSME2,UBE2D1,RPA3,ANAPC15,RFC5,PSMD6,ANAPC2,PSMB9,RFC3,YWHAG,UBE2V2,H2AX,CDKN1A,ANAPC16,CCNB1,PSMD12,MDC1,UBA52,PCBP4,YWHAH,PSMD10,YWHAZ,PSMA5,RMI2,PSMB3,H2BC14,RFC2,YWHAB,MDM2,TP53,PSMC3,PSMA1,RPS27A,ANAPC11,PSMD4,RBBP8,MCM3,RAD1,ORC6,PSMB4,CDC23,BRCA1,SEM1,NBN,ANAPC4,CDC7,PSMD1,PSMB2,PSMA6,SUMO1,MAD2L1,MCM8,TOPBP1,BABAM1,PSMC1,COP1,UBE2N |
| 5.944e-06 | -12.03 | BYSL (bystin like) | protein interactions | 705 | 337 | 132 | 19454 | 5460 |
LMNA,RPA2,MRPS34,WTAP,HEXIM1,RPL26L1,TFIP11,ATG16L1,RPS14,NF2,WDR3,RPS15,AATF,LDOC1,SIRT7,PNO1,RPA3,DVL2,RC3H2,UBE2H,NRP1,DHPS,RACGAP1,CEP70,RPS17,TRIM54,SMURF1,ZNF330,RPS3,ZMAT5,RPS20,RPS12,ZNF655,RTRAF,TRIM27,DNAJC2,RP9,NUPR1,RPSA,CCT5,SRFBP1,THAP1,NOC4L,SMN1,MEPCE,RPS13,STX11,KATNAL1,BHLHE40,MRPS18B,HAPSTR1,CHCHD1,SNRNP70,SSX2IP,RPS2,CSNK2A1,COPS5,RPS27L,RPS16,FZR1,SPPL3,NOP9,ZBTB2,KRR1,SYNCRIP,PWP2,TSR2,PIH1D1,TRMT112,RALYL,UFL1,FXR2,WASF3,COIL,RPS28,PYM1,EMG1,ZFP64,FTSJ3,DCAF4,CCT2,RPS26,RPS5,CUL3,EPS8,LMO2,MYC,ZNF668,RIOK2,ATP5F1B,MB21D2,USP16,ESR2,FAU,LMBR1L,PNMA1,RPS9,CHMP4C,PNMA2,RPS23,RPS11,BUD23,TOP3B,CSNK1E,TULP3,TNPO2,RPS7,TRAF2,ZBTB14,TRIM37,RPS4X,RPS27A,MRPS17,CDCA7L,CCT8,MRFAP1L1,RPS24,PICK1,WDR12,DDX1,MRPS26,CDC23,IFI16,GAS8,DDRGK1,XPO1,TCP1,NOB1,FAM98A,PHB1,CEP57L1,KRT8 |
| 5.948e-06 | -12.03 | ECH1 (enoyl-CoA hydratase 1) | protein interactions | 1891 | 219 | 92 | 19454 | 5460 |
DNAJC4,SSX2IP,COQ10B,ETV6,AIFM1,COQ8A,KLF9,PLGRKT,DBT,GPAM,AURKAIP1,SERPINB9,NDUFS3,KLF10,SFXN1,SEPHS1,HUWE1,ATP5F1A,UBE2H,PTPMT1,PAFAH1B3,CCNF,TRAF1,VIRMA,RPGRIP1L,PRKCE,NDN,CDK7,MTRES1,ACACA,EIF2B3,SPRYD4,RPA2,RAB9A,ARFIP1,APMAP,RPA3,BCL6,TOMM20,NME4,ACP6,ETFRF1,YWHAG,AGR2,TLR10,RHOG,GSTO1,GATD3,HDHD5,COX14,TMEM237,CNTROB,LYRM2,HNRNPL,ADCK1,ELF1,HEXA,PRSS35,RAF1,FAM136A,PDHA1,CHMP4C,COX8A,UBE3A,ZC3H7A,OPA3,NDUFA4,SCYL2,TRIM37,PSMA1,CHCHD2,TRIM26,TIMP1,RAB11A,CUL3,MYC,AUH,BOLA1,NDUFAF4,TAMM41,DUSP22,DHRS4,BET1,TOMM22,PIH1D1,SDHAF4,HDAC5,BOLA3,DNAJC22,EEF1G,FXR2,HSCB |
| 5.970e-06 | -12.03 | CAP1 (cyclase associated actin cytoskeleton regulatory protein 1) | protein interactions | 10487 | 179 | 78 | 19454 | 5460 |
DNAL4,SIRT7,BAP1,RPA3,HSPA5,MARS1,PYGB,NUCKS1,GPC1,CFTR,NEK7,PRDX3,CAPN1,TPD52L1,UBE2M,RARS1,HSP90B1,RPA2,AP2M1,RAN,VDAC2,CCNF,VIRMA,ESR2,MAT2B,PSMD6,ACTB,MCM3,TUFM,MCM4,UFD1,CFL1,PSMA4,HNRNPC,CUL2,CUL3,MYC,CAP2,MAT2A,CTSD,HTRA2,UBE2H,HSP90AA1,ATG3,BRCA1,SCPEP1,ERO1A,HAPSTR1,PABPC1,NEK9,RNASEH2C,RAB1A,HSPD1,MCM6,G3BP1,KRAS,HNRNPF,EEF2,TRAF2,SOX2,EEF1A1,RRM1,RAF1,CHMP4C,EZH2,ACTA2,SYNCRIP,PSME2,NUP35,HSP90AB1,MYL12A,TPM3,GAPDH,ATG7,BCL7C,GSTM3,KARS1,AGR2 |
| 5.970e-06 | -12.03 | NCSTN (nicastrin) | protein interactions | 23385 | 179 | 78 | 19454 | 5460 |
SNRPD2,SMU1,TRMT6,CCNF,LMBR1L,MAD2L2,SRC,YES1,LGALS3,ATP5F1A,CUL3,NOP16,SMARCA5,RRP7A,EPHA2,MARCHF3,ATP1A1,FTSJ3,LMNB1,RAP2A,VIPR1,PSEN2,TMEM106B,RFC4,SAP18,TOMM20,NF2,PSENEN,KLRD1,TIMM29,TAFA1,RPS14,CSNK1G3,TRMT112,RPA2,USP39,MAGED2,SRSF1,RAB31,SLC25A12,SRSF10,TOP1,PRNP,NOP58,MARCHF4,TRA2A,COMMD5,LAMP2,SMAD4,SPP1,SLC2A1,YIF1A,SEPTIN7,EWSR1,TOP2B,BACE1,SFXN1,NDUFB5,SLC25A5,SSRP1,RIGI,MEPCE,FASTKD5,PSEN1,SRPRB,APH1A,THRAP3,HNRNPF,ERLIN2,RPS7,CLEC2B,TPBG,PLD3,TMEM14B,SMARCB1,RPS11,IK,SURF4 |
| 5.978e-06 | -12.03 | COPS7B (COP9 signalosome subunit 7B) | protein interactions | 64708 | 129 | 60 | 19454 | 5460 |
SYCE3,COPS7A,CUL3,CUL2,ATP5F1A,FBXO7,DCAF4,YWHAZ,NCKIPSD,COP1,STK11,SYT2,FBXO22,TENT5C,DYNLL1,UBB,VIRMA,NMI,JUNB,CPSF4,FBXO42,DET1,RPA2,RNF7,HEXIM1,UBE2M,RPA3,BAP1,FBXW4,APPBP2,SKP1,HSPA5,DCAF4L2,AP5S1,COPS5,FEM1B,CRBN,DCAF11,USP15,WDR6,COPS2,DCUN1D1,COPS7B,FAM98A,MIF,PPIA,HSP90AB1,ASPM,TULP3,RHOBTB1,EWSR1,HECTD3,FBXO11,UBE3A,NEDD8,KRAS,APBB3,COPS4,EIF3E,RIGI |
| 5.978e-06 | -12.03 | TIMM29 (translocase of inner mitochondrial membrane 29) | protein interactions | 90580 | 129 | 60 | 19454 | 5460 |
PARL,NDUFAF4,CHCHD3,DLST,TACO1,LMBR1L,CD79B,CHCHD6,MRPS16,FAS,SLC25A51,NDUFS2,SLC7A1,RPA3,DLAT,MAVS,SAMM50,MRPS34,RPA2,CDK1,NDUFA5,MTX2,TOR1AIP2,TOMM22,RBFOX2,TIMM10,NEK7,AGK,SLC25A12,MRPS23,NDUFS8,RAMP3,COX4I1,AIFM1,MRPS9,CDCA3,SMIM12,ATP6V1D,HAX1,UPK1A,MRPS26,MRPS35,COX5A,SRPRB,KRAS,FKBP8,EDEM2,NDUFA4,SFXN1,MRPS18B,CLPB,NDUFS3,AQP3,PDHA1,ITGB8,AP1S2,ATP5PB,APOO,FAF2,NCSTN |
| 5.981e-06 | -12.03 | CHERP (calcium homeostasis endoplasmic reticulum protein) | protein interactions | 10523 | 251 | 103 | 19454 | 5460 |
UBE2H,RBM7,PIP4K2C,AR,ROCK1,SRPK2,VIRMA,YES1,PRKRA,CSNK2B,CCNF,RPS3,RPLP0,HNRNPH3,RPA2,GRM2,SNRNP27,FGF13,SF3A1,RBFOX2,RPL4,STK38,MIRLET7I,RNF113A,RPA3,DDX46,RBM23,SIRT7,RPS2,SMCHD1,SNRNP70,PPIL4,RBM17,CDC5L,RPS16,FZR1,MIRLET7G,PRR3,MIR106B,KRR1,ILF2,MIR200C,RPSA,PSMB10,MIRLET7C,SNRPG,TOLLIP,RPL3,HAPSTR1,DHX9,EMC2,SNIP1,MIR363,RIT1,H1-1,SNRPB,MYC,MIRLET7D,RPL19,SNRPB2,TAX1BP1,RPL35,SNRNP40,SNRPD2,SF3B4,SNRPD1,AGGF1,LARP4B,H1-5,PABPC5,UFL1,SF3B1,COMMD2,DDX23,HNRNPA1,DDRGK1,WWP2,FRA10AC1,DHX15,RPS10,HNRNPL,COMMD6,SNRPA1,SNRPD3,RPLP2,SRSF1,STK16,SNRPE,SMNDC1,H1-3,CCAR1,SRSF4,PDE6A,TRIM26,LASP1,H1-6,KRAS,TRIM21,EWSR1,SRSF7,HSPD1,RPL31,ARGLU1 |
| 5.994e-06 | -12.02 | DAZAP1 (DAZ associated protein 1) | protein interactions | 26528 | 151 | 68 | 19454 | 5460 |
RPA2,CTBP1,CARHSP1,UBE2M,AKR1A1,PIH1D1,ATP6V1C1,PRMT2,CFTR,AATF,RPA3,SOD1,SNRPA,GLOD4,ADK,BRCA1,SERPINH1,RAB2A,MYC,LRRC73,CUL3,CUL2,TIA1,CFL1,AR,CAPG,PRDX2,TAGLN2,DYNLL1,SNX3,SNRNP40,UBE2L3,SH3BGRL,SNX12,EZH2,PIR,PDHA1,TRAPPC13,NUPR1,RAF1,RBM12,NEDD8,G3BP1,ARF4,RAB1A,SLC39A7,EWSR1,IDH1,IGF1R,HNRNPD,CBL,NQO1,CRIP1,PRDX1,GPR171,WWP2,HNRNPA1,COPS5,CAND1,HNRNPL,AASDHPPT,NUP35,PHB1,FUBP3,EED,TRAPPC10,MTAP,FAHD1 |
| 6.051e-06 | -12.02 | PRLR (prolactin receptor) | protein interactions | 5618 | 27 | 19 | 19454 | 5460 |
PPIA,SOCS2,VIRMA,JAK2,PLPP6,CSH1,GHR,H1-1,VAV2,PRL,YWHAZ,FBXW11,SOCS3,YWHAG,CISH,CREBBP,INSIG2,GH1,PTPN11 |
| 6.051e-06 | -12.02 | CXCL2 (C-X-C motif chemokine ligand 2) | protein interactions | 2920 | 27 | 19 | 19454 | 5460 |
PIK3R1,XCL1,CXCL12,EPS8,COPS5,CXCL1,CCL11,CCL5,CCL28,CCL21,CXCR1,CXCL3,CXCL14,ENO1,PLG,CXCL11,CXCL9,DUSP3,CCL8 |
| 6.088e-06 | -12.01 | RNF11 (ring finger protein 11) | protein interactions | 26994 | 165 | 73 | 19454 | 5460 |
RTN4,RNF11,PHB2,UBE2D3,TOM1L2,RAB6A,TRAM1,UBA52,GTF2H4,CSNK1G3,STAMBP,WWP1,SDCBP,MSN,AP2M1,CSNK2B,VDAC2,OPTN,VAMP3,SRC,USP5,SMURF1,UBE2V2,UBB,UBE2L3,CHCHD3,PSMD6,TAX1BP1,TXN,STAT1,PSMD4,USP14,PSMD1,TNFAIP3,AKT1,AP2A1,PSMD14,S100A11,MYO6,UBE2E3,DDR1,SAR1B,RPS27A,PSMD12,HUWE1,TNPO2,UBE2V1,DDX39A,TBK1,HGS,AP2S1,SLC25A24,BMPR2,TFRC,S100A8,PHB1,UBE2N,CCDC127,DCUN1D1,QPCTL,CSNK2A1,UBE2E2,WWP2,USP2,PSMD3,DRG1,SLC20A1,PSMD7,SNRNP70,PSMD10,IKBKB,SMAD4,UBE2D1 |
| 6.095e-06 | -12.01 | positive regulation of immune system process | biological process | GO:0002684 | 986 | 353 | 18204 | 5365 |
EIF2B5,CTNNBIP1,TLR8,IFI16,CCL1,PQBP1,TRIM3,ZNRF1,PIK3R1,EXOSC3,MOG,VEGFA,SEMA7A,IL23A,SMARCB1,TICAM1,IL15,TLR1,LEP,CD40LG,PDE4B,NECTIN2,CD1A,THY1,HEXIM1,PHB2,SRC,IL18,P2RY12,IFNG,ICAM1,PIK3CA,CD47,IL17F,F7,CTLA4,NINJ1,TRIB1,TBK1,CYRIB,XRCC5,CCL19,EEIG1,TLR5,VAMP3,DPP4,TICAM2,TLR10,CD1B,TLR2,RARRES2,TRAF6,CD38,CD2AP,CACNB4,NFKB1,KCNJ8,IL15RA,FOS,HCLS1,PSPC1,CCL2,MAP2K6,IL2RA,TASL,TRIM5,STAP1,STK11,CREB3,FCGR2B,TESC,KLF10,OTULIN,CD40,NLRP1,CLU,SYK,TFRC,YES1,SELENOK,MED23,TRIM62,KMT5B,PIK3AP1,GPAM,KLRC2,VSIR,CD2,MIR30B,MIR21,LCP2,LILRA2,RGCC,SH2D1A,CD99L2,ZBTB16,RTN4,IFNK,TLR9,SMARCD3,CD80,CD36,POLR3F,WNT10B,NMI,VAV2,CLEC6A,RIGI,SIN3A,MAD2L2,KLHL25,VEGFC,PELI1,SMARCE1,FLOT1,OXSR1,HAX1,DHPS,MATR3,HSPD1,CD274,FOXP3,PNP,ACTL6A,CD79B,CD86,IL6,CSK,RSAD2,SPG21,BAX,IL12B,MMP14,SLC7A1,DDX1,FCER1G,FGR,UBE2K,POLR3B,STOML2,FOXP1,LAT2,CRKL,CNR1,KLRD1,UBE2N,MIR130A,PAK2,TGFBR2,IL2,KIT,CD14,TNFSF13,XBP1,BAD,PRKCE,LACC1,TIRAP,PLA2G5,STX7,JAK2,STXBP1,ITGA2,TLR6,NCR3,MIR136,IL1B,AKT1,PPP3CA,TOX,CCL24,KLK5,SHLD1,TNFAIP3,CALR,KARS1,NFKBIA,IGF1,EP300,CD247,CXCL13,LIPA,IRAK4,PRKCQ,SLA2,CD3G,CHRNB2,IL7,EIF2B2,ATAT1,ITK,B2M,TRIM15,IL34,IKBKB,RBCK1,EPO,HMCES,LGALS3,TLR4,NONO,CCL8,PTPN11,TOMM70,MICB,HSPA8,RAC2,PLPP4,NKAP,IL13,NEK7,IL21,CLEC7A,MADCAM1,CTSC,SPPL3,IDO1,CD1E,CXCL8,ACTL6B,MAPKAPK3,RHOH,TMEM126A,PLSCR1,PDCD1LG2,AIF1,TIFA,CCR2,CD1C,NLRP3,PRKCA,RB1,CGAS,RAG1,CDKN1A,SPHK2,LSM14A,ICOS,CXCL10,TNFRSF14,MZB1,DUSP10,CD226,AGER,PYCARD,HRAS,CXCL12,BCL6,HFE,MBL2,CD1D,HMGB1,PHB1,TRIM6,LY96,RPS3,VAMP7,TRAF2,MIR145,CX3CR1,TESPA1,IL10,XCL1,CX3CL1,CACNB3,SLC39A10,TNF,ACTB,PSEN1,CD81,LILRB4,CD4,PTN,PLPP6,CD46,AQP3,IL4,TACR1,MYD88,RUNX1,SOCS5,IFIH1,MSTN,MEF2C,CBFB,CD28,SWAP70,BLOC1S3,RC3H2,MAVS,TAB1,TYROBP,IFNB1,CAV1,NCR3LG1,RNF34,IRF3,USP15,HSP90AA1,BTN2A2,IL6ST,LILRB1,BCL10,HTR2A,IL12A,MIF,CCL3,CD83,SASH3,MIR142,CREB1,TLR3,DEFB124,GPSM3,CCL5,DNAJB9,EFNB1,BECN1,IFI35,CCL21,TRAF3IP3,OAS1,FCGR1A,CCR1,PRKCB,FOSL2,LTA,NLRP6,IRF7,TLR7,IL5,CCL20,TNFSF18,CREBBP,STAT6,KLK3,CCR7,CCR6,C1QC,VAMP8,DHX9,PTPN22,IL2RG,NCK1,EIF2B3,RAB29,FGF10,IL1A,TGFB2,FCN2,CLPB,CD209,NOTCH2 |
| 6.120e-06 | -12.00 | LSM11 (LSM11, U7 small nuclear RNA associated) | protein interactions | 134353 | 47 | 28 | 19454 | 5460 |
SNRPB,XPO1,TAF5L,RIT1,ILK,MRPS26,MRPS25,ZNF473,FOSL2,PRMT5,TMEM74,ESR2,SNRPD3,SNRPN,WDR77,SNRPE,GEMIN7,LSM2,RAB19,MIR20A,LSM10,MIR10B,SMN1,SNRPG,FTL,COIL,MRPS17,KRAS |
| 6.197e-06 | -11.99 | GSTO1 (glutathione S-transferase omega 1) | protein interactions | 9446 | 97 | 48 | 19454 | 5460 |
GSTT1,HSPE1,ETFA,HINT2,TAGLN3,ATP5PF,PPME1,CCS,PGM1,RAF1,TP53,GSTA4,NUDT9,GATD3,HEBP1,PYURF,HSPB1,FGR,LYPLA2,EEF1G,TXNL1,PRDX6,RPA3,SOD1,BAP1,PML,GSTP1,GSTO2,RPA2,CFTR,PCK2,CAPN1,SUCLG2,TAGLN2,LDHA,TXN,TENT5C,ACTB,TRIM24,CCNF,FKBP1B,UBE2H,MDH1,BAG3,GMPS,ACO2,TNFAIP3,PMPCA |
| 6.197e-06 | -11.99 | AKAP11 (A-kinase anchoring protein 11) | protein interactions | 11215 | 97 | 48 | 19454 | 5460 |
MAP1LC3B,SOX2,ETFB,RPL28,LECT2,PICK1,RABGGTB,ZYX,HAX1,YWHAB,SMAD4,YWHAG,HSPB8,YWHAH,DYRK1B,EGLN3,DNAJC1,KRT8,SRP14,PRKCA,VAPB,SEC62,PPP1CB,VPS28,NAPG,HSCB,DERL1,KLHL28,TIMP3,CDKN2AIP,UBE2H,YWHAZ,MYO6,PRKACB,H2BC9,PPP1CC,MLF1,CUL3,SFN,SFRP4,DYRK1A,VIRMA,NDN,FAM43A,AP2M1,GSK3A,SEC61B,DCLRE1C |
| 6.220e-06 | -11.99 | Chagas disease (American trypanosomiasis) | KEGG pathways | hsa05142 | 102 | 57 | 7161 | 2463 |
MYD88,AKT3,IFNB1,TGFBR2,FAS,NFKB1,TRAF6,CCL5,PPP2R1A,IL6,SMAD2,TLR9,IL10,GNAQ,IFNG,CCL3,TGFB2,GNAO1,FOS,GNA14,GNA11,CD247,CXCL8,CD3G,PPP2CB,NFKBIA,IL2,IL12A,TICAM1,GNAI2,PPP2R2C,AKT2,JUN,IL1B,TNF,PIK3CA,CCL2,TLR2,PIK3R3,PIK3R2,AKT1,IRAK4,SMAD3,PLCB2,GNAI3,PIK3R1,TGFB3,C1QC,FASLG,IKBKB,MAPK10,TLR4,TLR6,CALR,PLCB1,IL12B,IFNGR1 |
| 6.220e-06 | -11.99 | Chagas disease (American trypanosomiasis) | KEGG pathways | ko05142 | 102 | 57 | 7161 | 2463 |
IL1B,PIK3CA,CCL2,TNF,PIK3R3,TLR2,TICAM1,PPP2R2C,GNAI2,JUN,AKT2,MAPK10,IKBKB,FASLG,TLR6,TLR4,PLCB1,CALR,IFNGR1,IL12B,PIK3R2,PLCB2,SMAD3,IRAK4,AKT1,PIK3R1,TGFB3,GNAI3,C1QC,PPP2R1A,IL6,SMAD2,IL10,TLR9,IFNB1,AKT3,MYD88,NFKB1,TGFBR2,FAS,CCL5,TRAF6,PPP2CB,CD3G,CXCL8,CD247,NFKBIA,IL2,IL12A,GNAQ,CCL3,IFNG,FOS,GNAO1,TGFB2,GNA11,GNA14 |
| 6.293e-06 | -11.98 | regulation of developmental process | biological process | GO:0050793 | 2540 | 843 | 18204 | 5365 |
NPY1R,SYK,FGF16,PITHD1,PROM1,ACVR1B,SAV1,RAB14,CD40,NME2,FBXW7,SGF29,HDAC6,EAF2,TESC,NOG,STK11,CD2,VSIR,CERS2,MIR101-1,ATRAID,PARP2,WEE2,GPAM,TRIM32,GLUL,PDCD1,CYB5D2,GPR171,SLC23A2,BIRC2,DMPK,SGMS2,G6PD,RARRES2,TLR2,CYP1B1,SLC12A2,NTN4,PTHLH,PIAS1,RNF10,EEIG1,XRCC5,CYRIB,STAT5A,CDC42EP3,NHERF1,IL2RA,NPPC,CCL2,DUSP6,MAPKAPK5,JMJD8,MIR16-1,CCDC85B,IL18,TMEM176B,UQCC2,OLFM2,UTP25,PIK3CG,MIR939,THY1,MIR140,FASLG,RNF41,PAFAH1B1,IL17F,TIAM1,PIK3CA,ZC4H2,FIG4,TCIM,NLGN1,PDCD4,ROCK1,NEO1,CAMP,MIR15A,SYT2,MIR143,NR2E1,PIK3R1,SLC6A6,OSM,YWHAZ,MIR30E,AMIGO1,FZD4,ADIG,CAPN2,NIBAN2,STIM1,CAMK1,HSPB6,IL15,MIR137,FGF23,PRELID1,MTPN,LLPH,IL23A,MTA2,VEGFA,NF2,ELAVL4,MIR182,SLC45A3,WNT7A,PPP3CA,VSTM2A,BMP1,AKT1,IL1B,TGFB3,AGR2,GPC1,SAP30,IGF1,NFKBIA,BRD9,DIO3,SPRED1,CNOT2,TCF23,MYL12B,MIR675,SKIC8,ASPA,CALR,GH1,TNFAIP3,RBBP4,MAP1B,VDR,MT3,RETN,OXTR,TOX,XBP1,DLK2,MIR320A,PID1,ANP32B,FLRT3,KIT,CCND1,IL2,MIRLET7B,TGFBR2,PAK2,MIR130A,AR,RND2,SOD1,MIR492,NR1H2,FGF1,MIR125A,GNB3,PLA2G5,NRP1,CDK5RAP3,RGMA,MIR448,PPP1R12A,ACTL6A,PLXNC1,FOXP3,AKT3,FUT1,ERRFI1,MIR1224,BVES,MIR130B,HAX1,SPRY1,GPR137,TMBIM1,EMC10,SMARCE1,CDC42SE1,DAPK3,KLHL25,GNRH1,TMEM100,MIR223,LRRTM1,NKX3-2,GPM6B,MOSMO,MMP14,EIF4E,MIR379,BAX,TP53INP1,SDC2,ID4,HAPLN2,IL6,ASPM,MMP9,CD86,ZMYM4,MIEF1,SMARCD3,TNFRSF1B,TLR9,PLCB1,HDAC3,ADM2,ZBTB16,SFN,SYT4,TNIK,CDC73,IFNA2,MMP20,SSBP3,MAD2L2,PAX6,MIR204,PLEKHO1,SIPA1L1,FOXS1,WNT10B,CDC42EP4,CD80,FGF7,HMG20A,DDAH1,CLDN4,BCL6,RHOU,CXCL12,PLAC8,CDK5,EMILIN1,MIR98,TBC1D24,HECW1,ITGB8,DUSP10,IL1RAP,ACTB,FGF3,TWSG1,TNF,TBCCD1,BRMS1L,MIR1298,CX3CL1,RBPJ,MUL1,NAB2,TESPA1,LRRTM2,RUVBL1,ING1,ZHX3,GJA1,MIR214,MIR17,NLRP3,RBM38,ARF6,CLDN3,FOXC2,IRF4,PALM2AKAP2,TENT5C,CDK9,CDKN1A,ILK,NAB1,LRRC4B,ZNF365,CITED1,RB1,MIR99B,ITGAV,MGP,CRABP2,TRIP4,GHR,LAMB2,BRINP2,PPIB,ZBED3,KLF4,PAX9,DLG4,CER1,APLNR,TLR4,ACTL6B,SDCBP,BRINP1,MDM2,STK4,MAEL,FKBPL,TP53,TNFAIP6,MIR1-1,SYNJ2BP,DDX5,SOD2,EHD1,IMPACT,CDKN1B,PPP2R1A,NREP,SUFU,RHOG,PI16,UFL1,CXCL13,MIR212,MIR503,LGALS3,HMCES,S100B,CYP27B1,ST7,B2M,CCSAP,ATAT1,LHX2,DROSHA,HEXB,GTF2I,DKK1,TMEM182,SPP1,MIR25,FAM20C,RFLNA,SEMA5A,ISG15,STAT6,BHLHE40,HAND2,MBD3,ADRB2,LRP3,PPFIA2,ADD1,MIR9-1,PAEP,PROK1,GHRL,RGN,NDFIP1,RHEB,SOX9,STAT2,SNAI2,CBLN1,DICER1,FIS1,BRINP3,IFRD1,DLG1,IL5,MIR29C,ING5,KDM1A,SAP30L,TOB2,HGS,HDAC5,MIR511,MAP2K1,PPP1CC,CCR1,TMEM176A,YWHAH,FRZB,CCL3,HNF1B,MIR132,LILRB1,IL6ST,BTN2A2,CSF2,UST,HEY2,C1QL2,OPRM1,STK3,CFL1,EFNA3,RORB,ZDHHC15,ZNF322,CST3,EPHA4,TLR3,FERMT2,IGF1R,MIR302B,SFRP1,FLCN,SOCS2,LRRTM3,NUPR1,AGO1,HTRA2,BEND6,SOCS5,LDLRAD4,TAF5L,IL4,NPTN,FXN,AQP3,CBLN2,MIR149,CD46,IGFBP3,MIR146A,TYROBP,CMA1,MIR150,SEPTIN7,RUVBL2,ING2,EFNA5,MIR205,MACROH2A2,MINAR1,KLF10,NKX3-1,FCGR2B,ADIPOR1,SARM1,SMAD3,MIR24-1,WNT2,CCN3,SLITRK2,RAP1A,KMT5B,TRIM62,TFRC,FXR2,TRAF6,GADD45A,NLGN2,AGGF1,MIR222,LRTM2,LRRN1,CCL19,TRIB1,MIR378A,CTLA4,NINJ1,SYCE3,BMPR1B,CHI3L1,DISC1,HCLS1,FOS,PML,SOSTDC1,IL15RA,TERT,NFKB1,GNA11,FGF13,MGARP,TNFSF12,MTMR2,SRGN,SRC,DAG1,MIR34C,PHB2,FGL2,WIF1,ATF4,KRIT1,EPS8,LEP,CAMSAP2,MIR34B,MIR873,IFNG,HOXB8,LGR4,MIR100,BRMS1,IRF1,PQBP1,MKLN1,FLRT2,ZMYM6,TLCD3B,PGK1,CCDC3,LMO3,NTRK2,SHOC2,BLOC1S5,CTNNBIP1,METTL14,MIR153-1,PRMT6,FBXO7,SOX3,NFE2L2,BMPR1A,MIR181C,SMARCB1,MECP2,SLITRK1,BMPR2,TFE3,SEMA7A,MIR29A,EXOSC3,UBASH3B,EID2B,PRMT5,SMAD4,INO80E,DRD3,ARHGAP15,AMELX,SDHAF2,DR1,EP300,TTL,PDCD10,WDR77,CTNNB1,SHLD1,CTSK,NPR2,CCL24,RALA,CDC42EP2,TNFSF13,ADRB3,MIR377,LMO4,MIR206,EIF2AK2,RLN2,CDK12,SS18,CTDSP1,GAMT,PLAA,MIR221,CARTPT,SLC8A1,CRKL,MSN,BCL2L1,PTEN,JAK2,STAT1,VLDLR,MIR573,L1CAM,TMEM215,DVL2,GSK3A,BAD,FGD2,CD34,PRL,JUNB,OTX2,PNP,LDLR,MIR885,MTA3,MIR10A,NEUROD2,ADRB1,FLOT1,PPARA,GPR37L1,VEGFC,CXCL9,FOXP1,YWHAG,FGR,MIR185,UBE3A,IL12B,SLITRK5,BGLAP,BTG1,MIR107,DNM2,SMURF1,EMP2,RTN4,MIR548C,ELAPOR2,GPRASP3,CREBL2,UBE2B,GLIPR2,RGCC,JAK1,LST1,CPNE1,MIR375,ANAPC2,MSX2,INHA,MIR21,MIR30B,MIR519D,SIN3A,TSPAN18,MIR210,CD36,HMGB1,BCL7B,MIR495,CORO1C,KCTD11,MME,EPHA2,KLK6,INO80C,NTNG2,LBX1,RGS2,CDC42SE2,PTK7,TRIM46,GABPA,S100A10,CXCR4,ZNF304,MIR361,MIR23A,LRRC24,AGER,TAPT1,RHOB,BATF,CCR3,LBH,MIR505,RBBP7,ADIPOQ,PLAAT3,RAF1,ROCK2,IL10,FERD3L,MIR640,NKX6-2,MIR145,CCM2,CX3CR1,MSX1,PRKX,CNTNAP1,TRIM6,TMEM106B,PRKCA,CFTR,NEFL,LDB1,ACVR1,CCR2,F2,GAS2,BCL7C,RHOH,CXCL10,CFDP1,ASIC2,RAG1,ANKH,MIR424,COCH,ADNP,CTTN,VASH1,NKAP,FGFR1,P2RY1,PTPRQ,HELT,PRDX2,AAMDC,CCL11,TOMM70,PTPN11,MIR590,HUWE1,CDK6,TFPT,LRRC8A,DDIT3,MIR133B,CXCL8,LPAR1,CTSC,MITF,CLEC7A,MIR34A,IL13,GAB1,BTG2,TSPO,RAP2A,STK24,F11R,MIR193A,MIR106A,JUP,GPNMB,RHOJ,FAXDC2,ZNHIT1,RACGAP1,SP1,CLSTN3,PPARG,SFRP4,MIR30A,SLC6A4,EPO,TPBG,TGFB1I1,IKBKB,IL34,MYRF,MKKS,YTHDF2,MIRLET7G,FBXO22,IL7,EZH2,UPF3B,CHRNB2,CHRNA7,ADCK1,CEACAM5,SOX2,C1QC,KLK3,TPPP,PROX1,MTDH,WASF3,GREM1,KRAS,NOTCH2,MBD5,SLC6A3,TGFB2,IL1A,MIR144,FGF10,SPRED2,ADAMTS1,IL2RG,TADA3,MIR20A,FZD3,CTNNA1,TNR,MAFG,ADAMTS20,SMAD1,MIR200C,ATP2B4,MMD,IRF7,MACROH2A1,FOSL2,LTA,PRKCB,SETD3,TWIST2,SASH3,CD83,HTR2A,OSR2,MARCHF5,MOV10,CDK1,SMAD5,TGIF2,SYNDIG1,MTCH2,CDK5R1,ZMYM3,MIR106B,FITM2,SOS2,DLX1,MYC,CREB1,MIR126,SLC20A2,CDC20,MIR142,HSPB1,MIR208A,ZMPSTE24,RUNX1,SMAD2,MIR342,TCTA,MIR31,BRCA1,PTN,CD4,LILRB4,MTM1,EGR2,PSEN1,CAV1,TRIM11,IFNB1,SOCS3,MEAF6,RC3H2,FKBP1B,VGLL4,CD28,PTPRZ1,HSP90AB1,CBFB,MEF2C,CAV3,MSTN |
| 6.309e-06 | -11.97 | EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1) | protein interactions | 9695 | 202 | 86 | 19454 | 5460 |
MTM1,ROCK1,STUB1,WDR45,SGTA,SEC61B,PIP4K2C,DNAJC10,ATG3,PSMD14,HSP90AA1,VMP1,VPS39,FBXO7,RNF5,PIK3R2,TMUB1,HSPA5,DNAJC3,TEX264,HSPA8,SYVN1,EP300,OR1M1,MTDH,SQSTM1,DERL1,P3H1,VPS18,SSR1,SAMM50,HSP90B1,METTL14,STX17,ANXA7,RRAGA,ATG16L1,SUFU,CAPN1,TMUB2,SEC62,EDEM3,DNAJB9,DERL2,LMAN1,ERLIN1,OS9,STT3A,ACSL4,WDR6,S100A8,TSG101,MCL1,MCOLN1,MUL1,ESYT1,BECN1,RNF139,RB1CC1,EI24,ATG9A,LAMP2,CALR,SELENOS,MAP1S,EDEM1,PPIB,ATG7,TBC1D5,MFN1,ERLEC1,FAF1,BACE1,RPN1,TAB2,SH3GLB1,RNF121,SESN2,SERPINA1,GNAI3,TBK1,CCDC47,TP53,SUPT5H,FAF2,ERLIN2 |
| 6.319e-06 | -11.97 | AMBRA1 (autophagy and beclin 1 regulator 1) | protein interactions | 55626 | 263 | 107 | 19454 | 5460 |
UBL4A,SOCS3,MAP1LC3B,TIMM8A,MLLT11,PPP4C,PSMC3,MAP1B,CLPB,TRAFD1,HUWE1,PSMA5,DYNC1I1,TTC4,SOCS2,RIGI,GPRASP2,COPS5,ELOC,BECN1,AKAP8L,DNAJC7,SSBP1,AIFM1,AIP,FZR1,TOMM70,PSMC4,CCND1,NTPCR,GABARAPL2,CNP,STAMBP,RPA3,MAIP1,DVL2,TRIM10,RNF113A,SQSTM1,GABARAP,HSPA5,SLC25A1,AKT1,TRIM32,PSMB2,TUFM,SDF2L1,TEX19,CHCHD4,CCNF,STUB1,PSMA6,RNF187,PSMC5,TECR,VIRMA,TOP3B,GABARAPL1,PPP2R1A,TUBA1A,HSPD1,NEK9,CCT8,BAG2,PSMA2,PSMA1,PSMD12,COPS4,PSMD3,CISH,PSMD10,FKBP4,TRAF6,HAX1,HSPB1,CBFB,PSMB5,MAP1LC3A,IGBP1,ATP6V1A,COPS2,CCAR2,EGLN3,PSMB3,ASB8,TIMM13,FEM1A,HSPA8,PSMA3,NDUFS2,UBE2D3,PSMC1,CCND3,COPS7A,MYC,PSMA4,SAMHD1,MLF2,CCT2,ATG3,FBXW11,HSP90AA1,PELO,LRRC28,DYNLL1,PSMD6,MAD2L2 |
| 6.325e-06 | -11.97 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1408 | 477 | 16828 | 4835 |
TSHR,RGL1,BIRC2,DYRK1A,TRIM27,FBXO32,PRKCB,RUNX1,SS18,EIF2AK2,NDE1,IGF1R,CX3CR1,LCP1,OTUD7B,SHC1,CDKN1A,DIRAS2,FGFR1,GYS1,PSEN1,SOS2,DIRAS3,YWHAH,TACR3,LMO2,NPY2R,MYEF2,MYD88,MGMT,ATP6V1D,GPR37,TRIM11,PRKACB,G2E3,HEY2,RHOB,MAX,USP2,FEN1,CSNK2B,ADRB1,CD46,PPARG,SPRY1,ERAS,BMPR1B,FBXO11,PTPN1,HECW1,TRIM37,WNT10B,TRAF6,IRF4,CCND3,RAB9B,PEA15,ADRB3,FGF12,EXOC1,EP300,JAK1,USP13,MLF1,LAMTOR3,STAT6,NUP62,COPS5,STAT5A,FGF3,STK11,MAP2K1,FGF1,WIF1,RIT1,CCNF,RAB9A,GRM8,MEF2C,RAB2A,IL1B,AR,BAP1,FZD4,TGFBR2,FASLG,RNF182,BRAP,TNFRSF1B,USP30,EXT1,JUNB,USP3,VCPIP1,RAB5C,MCHR2,RAF1,ZMYM2,CDC73,STK38,TCEA1,PPP2CB,PPP2R1A,KIT,RASL12,RAP2C,ZNRF1,EIF4B,JOSD1,DDIT3,TTL,CCR7,NMBR,IGF1,CSNK2A1,STK38L,IGFBP3,GRPR,SPHK2,ANAPC11,MAP2K3,MAP2K6,NRP1,TGFB2,STYK1,DDR1,PTGER1,TFPT,RAB23,RIT2,OGG1,LTA,CCR3,CBFB,RASL11A,LTBR,UBE3A,P2RY1,JUN,PIAS1,WWP1,SOCS4,S100B,UBE2A,GHR,POLB,TLR7,POU5F1,MSN,FGF16,AVPR1B,PPP2R5A,FANCG,STAT1,PAX6,IL1R2,TLR6,NKIRAS2,ACVR1C,MEF2A,SFN,RALA,STK4,PPP2R2C,FOS,ITK,CD79B,TNKS,ZBTB16,LAMTOR2,CCR5,TLR3,TLR1,GRM2,PRKAG1,RAB5A,MAP3K3,NEK2,VAV2,NFKB1,TIAM1,SENP5,AKT1,NFKBIA,MITF,OR51E2,RERG,IKBKB,SDHC,TLR9,APLNR,RRAS2,MSH6,RAP2A,PPP1R11,HRAS,NUP153,DKK3,OTUD6A,CNTNAP1,PTGFR,FBXO22,TFG,TP53,RND3,GNRHR2,NPY5R,EGFL7,P2RY4,CXCR4,CXCR6,WDR83,CISH,MDM2,USP14,RAN,SENP8,SOCS5,CREB1,BTG1,PTPN11,NOTCH2,EDNRA,PML,SOX3,CCR1,VEGFA,PSMD14,YWHAB,NCKIPSD,LIG3,PRKCQ,TLR8,PPP1CB,SHOC2,CD40,SLC6A2,USP16,PSMD7,DUSP6,CDK7,BMPR1A,HERC3,CD40LG,DIRAS1,NKIRAS1,PTGER2,MYC,CASP4,NTRK2,FRZB,CCND1,USP15,LPAR2,OTUD6B,SPOP,BCL2L1,YWHAG,CRHR1,FBXW7,TIRAP,CDK12,BAD,RASGRP3,ACVR1,DUSP1,NPY1R,CREBBP,PPP1CC,PDCD10,EPHA4,RBPJ,STAMBP,RBCK1,DUSP9,PTGER4,AGR2,GRM1,SDHB,CDKN1B,DEK,CXCR3,CCNA2,SYK,MAP3K11,PIK3R3,PTEN,DUSP10,CDC42,NCK1,RASL10A,YWHAZ,SRC,PSEN2,INPPL1,CAPN2,PTK7,USP8,RHOU,CCR2,TLR10,USP46,SMAD2,GNAQ,ATF3,SPRED1,LPAR6,PMAIP1,ETV6,MET,FZD6,HSP90AB1,IL1A,CAV1,SFRP4,TRAF7,PPP1R3C,TNFAIP3,KCNH8,RGL2,S1PR4,RAP2B,SOCS2,RALB,RB1,UBE2N,CTNNB1,SMURF1,P2RY10,CDK6,NCSTN,JAK2,FLCN,USP38,TRIM36,BIRC5,KLHL12,FGF23,USP39,WNT2,SFRP1,SPRED2,TLR4,ZNF668,PIK3R2,ADRB2,FZD3,TOP1,FGF13,FGF22,HSPB2,ADRA1A,PEBP1,STK3,PAK6,HSPB1,TRIM24,TGFB3,KDM2A,FGF10,RPS6KA4,TLR2,ELK3,GRB10,CSNK1E,HECTD1,PRKCE,PIK3R1,TFEB,AKT3,BCKDK,EWSR1,STAMBPL1,RHEB,PARP2,CAV3,NF2,EPHA2,FGF7,PPP2R5E,TACR1,SCLT1,CCR4,ERCC3,FAS,ATF1,WNT7A,TNF,APH1A,MAD2L2,UBE2V2,WWP2,RAP1B,RAP1A,CDC7,TFE3,ELK1,SAV1,STAT2,FOSL2,CSNK1A1,FGF17,CXCR1,RBBP8,ACVR1B,MRAS,USP5,GNAO1,EIF4E,RHOH,XRCC5,PIK3CG,RNF126,BAK1,NBN,IGFBP4,ELK4,CBL,IL2,IRAK4,SMAD4,PPP2R3A,UCHL3,RASD1,NLRP3,HSP90AA1,PRKCA,PPP1R1B,PARP11,SOCS3,BMPR2,BCL9,DVL2,LRP6,NFKBIB,RAC2,EXOC2,STK24,THRAP3,RC3H2,CNTN1,PRKAB1,HECTD3,DKK1,HERC4,PRCC,BCL6,KRAS,GSK3A,TNFSF10,FURIN,MNAT1,CDH11,SMARCB1,PIK3CA,CHIC2,APEX2,SUFU,TAB1,UBE2B,FBXL19,TRAF2,BRCA1,TLR5,TPD52,APEX1,NTRK3,GAB1,LASP1,AKT2,P2RY12,PICALM,CDK4,ANKIB1,BCL10,GH1,BAX |
| 6.364e-06 | -11.96 | JUP (junction plakoglobin) | protein interactions | 3728 | 453 | 170 | 19454 | 5460 |
TRIP4,TMT1A,RBM3,OAZ3,RUVBL2,G3BP1,KRAS,EPHA4,GJB1,RPL28,FLOT1,RAB8B,B3GNT2,MAX,SLC25A44,EEF2,CTNNA2,EZH2,PTRH2,NME1,CHMP4C,CCR1,RND3,MOB3C,RAB35,FABP5,PHB1,EED,GJA1,NRSN1,RPLP2,RHOH,SPTAN1,DIRAS3,HSP90AB1,ATG9A,PTDSS1,HNRNPA1,YWHAG,MRPL9,YWHAH,CTNNB1,RHOG,CSTA,NCK1,HSPB1,BCL2L1,PEBP1,DDX39B,XRCC5,BIRC2,HSPA8,SLC35F2,RAB5A,EP300,PMAIP1,PHB2,STX7,CLDN4,RND2,NUDT3,MAP2K1,KLC2,PIH1D1,ARCN1,MYL6,VDAC2,PRDX2,DYNLL1,APEX1,ATP6AP2,DES,OST4,MYC,NFYA,CREBBP,CUL2,RAB11A,GRB10,SCN3B,SAMHD1,MCM3,LAMTOR1,MYO6,YWHAZ,LMNB1,BRCA1,RHOB,NTRK3,HSP90AA1,SNIP1,ABCE1,IGF1R,LIPA,HSD17B10,RPS13,PSEN1,CTNND1,INSIG2,TP53,EEF1A1,TFCP2,CDH8,ILF2,RNF8,RPL12,RAC2,ARF6,TOP1,STX6,MBD5,CAV1,ERCC3,GMPPB,COPS5,HDAC6,GAPDH,SHC1,FBXO34,RPS2,UPK1A,STYK1,RPL10A,RHOU,RPA3,FBXW7,PIAS1,HSPA5,ABCC2,ATG16L1,NFYB,NEK2,CDC42,ST7,CFTR,CDK1,VPS4B,RPA2,METTL14,STX17,FGFR1,GRM2,SHOC2,CCNF,GAB1,CTNNA1,PSMC5,GANAB,CALML5,B4GALT1,CFAP298,PTEN,MSN,RHOJ,GABPA,SMURF1,SRC,VIRMA,CIAO1,LILRA3,NTAQ1,ST13,AR,CTNNBIP1,DNAJC5,SPOP,PIP4K2C,CDC73,MAPRE1,UBE2H |
| 6.383e-06 | -11.96 | LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 51690 | 105 | 51 | 19454 | 5460 |
GXYLT1,SNRPD1,SNRPD2,SGTA,LSM6,GEMIN8,EPHA2,RIT1,MYC,CUL3,PRPF31,LDB1,SNRPB,LSM8,SNRPA,RAB29,PRPF4,TXNL1,PPIH,USP39,LSM2,KLC2,DDIT4L,SF3A1,SNRNP27,HNRNPL,PAIP1,ZNF511,SNRPD3,LSM5,EGLN3,RBM42,WDR44,RFX5,DDX23,FKBP4,LSM3,NPY1R,USP15,DDRGK1,KRAS,LSM4,MEPCE,SSRP1,SMN1,LSM14A,HNRNPA2B1,SNRPE,NUPR1,SART3,EXOSC8 |
| 6.394e-06 | -11.96 | SCY | smart domains | SM00199 | 42 | 25 | 9717 | 2575 |
CCL25,XCL1,CCL18,CCL21,CXCL13,CXCL11,CCL3,CCL20,CCL8,CXCL3,CXCL9,CXCL10,CCL1,CCL2,CCL23,CXCL12,CCL19,CCL17,CX3CL1,CCL5,CCL4L1,CXCL1,CXCL8,CCL24,CCL11 |
| 6.423e-06 | -11.96 | AKT1 (AKT serine/threonine kinase 1) | protein interactions | 207 | 596 | 216 | 19454 | 5460 |
TRAF6,BCL2L1,NQO1,PPP3CA,AHSA1,CDKN1B,BABAM1,RAB3D,PIK3R1,TRIM15,RGCC,STK3,PRKCQ,PPIA,CGGBP1,PSMB4,PTGDS,SOSTDC1,GJA1,NGB,EZH2,SNCB,RAF1,PPP2R1A,BPGM,RPS27A,CDKN2C,AKT2,MAP3K11,BAG2,BRCA1,YWHAZ,BLVRA,ILK,HSP90AA1,SP1,GRB10,RNF40,TUBB,UMPS,ACTB,GNB1,UBE2S,ENO2,BAD,SLC25A3,PSRC1,RPE,CDKN1A,PPP1CB,MLH3,RNF11,JADE1,TERT,RLIM,MUL1,TOPBP1,GMPPA,RNF14,HDAC6,MDM2,TMCC2,MAP2K6,EEF1AKMT3,PTPN1,SMAD3,CCT5,MTA3,TBK1,CTDSP2,MAP2K3,RNF115,RIGI,RNF20,TCOF1,FAF1,IGF1R,FXN,CASC3,NCKIPSD,EPHA2,PEA15,SMAD2,STK11,CSK,PPP1CC,AGAP2,AR,LDHA,UBB,ENO1,CTNNA1,POP7,CTTN,CCNF,GAB1,STUB1,PLP1,PTEN,TRIM24,GSK3A,HSP90B1,CARHSP1,OXSR1,UBA52,KDELR2,FBXW7,PFKFB2,USP8,NF2,PDHB,PIAS1,CSTB,RPA3,TMEM126B,PRKCB,IKBKB,H2BC17,HSPB1,PPP1R11,MAPK4,STK4,CTNNB1,NOL4,YWHAG,TCP1,HSP90AB1,CCT7,TRMT61A,CEP57L1,FBXO31,ZHX1,UCK2,SMARCB1,TOP3B,SOX2,TUBA1A,CCT8,FAM168A,PICK1,RUVBL2,RPS6KA4,CCT2,CKB,DNAJB6,MDH1,SFN,TBCE,MYC,CREBBP,MLF2,ISCA2,STAT1,ESR2,NFKBIA,VEGFA,MXD1,CTBP1,KLHL3,EEF1G,PHB2,CNKSR3,PEBP1,EP300,PCGF2,DDX5,HSPA8,CCNI,GPHN,LANCL2,BECN1,SMAD4,BCL10,MAGEB1,PLEKHO1,XAF1,GAPDH,CSNK2A1,CD81,FZR1,ALYREF,CDK6,NFE2L2,NHERF1,PIK3CA,TBC1D4,RNF8,TP53,CDK4,PREB,RASL10B,KDM4B,EFHC1,ATP1A1,PTPN11,AKT1,AKT3,TNFAIP3,SRPK2,SRC,ZBTB33,CREB1,PSMC5,FGFR1,HBB,CLIP3,RPA2,H2BC11,CAPN1,DDIT4L,CD2AP,HDAC3,HSPA5,IRF3,BAP1,TLR2 |
| 6.458e-06 | -11.95 | PF4V1 (platelet factor 4 variant 1) | protein interactions | 5197 | 21 | 16 | 19454 | 5460 |
CXCL10,CXCL11,CCL27,ALB,CCL21,CCL19,CCL4L1,CCL25,CCL11,CXCL13,H2BC9,CCL28,ATG9A,XCL1,UBA52,CXCL12 |
| 6.475e-06 | -11.95 | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | REACTOME pathways | R-HSA-72662 | 63 | 37 | 10285 | 3229 |
RPSA,EIF3J,RPS20,RPS16,EIF3D,EIF4A2,RPS24,FAU,EIF3E,EIF4B,EIF2S2,RPS3,EIF3G,EIF3K,PABPC1,RPS14,EIF4E,RPS15,RPS5,RPS27L,RPS7,RPS26,RPS28,EIF1AX,RPS10,RPS17,RPS4X,RPS12,RPS2,RPS23,RPS29,RPS11,EIF2S1,RPS13,RPS27A,RPS9,EIF4H |
| 6.523e-06 | -11.94 | TMEM209 (transmembrane protein 209) | protein interactions | 84928 | 143 | 65 | 19454 | 5460 |
LMBR1L,CCNF,RMDN3,SLC1A1,SEC61B,UBE2I,APLNR,CUL3,LMNB1,RHOB,FIS1,HTRA2,BAP1,RPA3,VIPR1,DERL1,RAB9A,RAB5A,STX7,PXMP2,CDC42,SEC62,OTULINL,RND2,ST7,RPA2,LMNA,FGFR1,SSR1,RAB35,PTPN1,HSD17B11,GJA1,RAC2,ARF6,DNAJC1,RHOH,DYNC1I2,EGLN3,DUOXA2,TMPO,RAMP3,LMAN1,NUP35,LAMP2,IFI16,ATG9A,SLC25A46,RAB5C,MARCHF5,RHOG,SLC2A1,ESYT1,NAB2,TMT1A,PSMA5,NUP107,KRAS,NUP153,MGARP,DNAJC25,RPN1,STIM1,AQP3,PTRH2 |
| 6.523e-06 | -11.94 | TMED9 (transmembrane p24 trafficking protein 9) | protein interactions | 54732 | 143 | 65 | 19454 | 5460 |
FAF2,UBL4A,RAF1,CCDC47,TP53,TMED7,TMEM60,RUVBL1,EMC2,TMED1,FGF3,DDX1,CDK5RAP3,NDUFV2,DDRGK1,MOV10,LMAN1,EIF2S1,FZR1,MIF,STX5,KLF3,RPA2,GRM2,FGFR1,UBAC2,SEC22A,CDC42,TOMM22,PGRMC1,TPT1,SEC22B,PIP5K1A,HSPA5,EMC1,HSCB,RER1,YTHDF1,TMED3,HSPA8,RABAC1,SF3B1,PMAIP1,RPA3,TMEM106B,NTRK3,NRP1,SERPINH1,GORASP2,NONO,TMED5,OST4,MYC,TMED4,ITM2A,TOM1L1,VIRMA,ESR2,DEK,THAP8,SEC61B,ACOX1,OPTN,LMBR1L,CYB5R3 |
| 6.687e-06 | -11.92 | NGEF (neuronal guanine nucleotide exchange factor) | protein interactions | 25791 | 74 | 39 | 19454 | 5460 |
ACTR1B,HCFC2,SFXN1,CTNND1,CMAS,EPHA4,SSR3,CSE1L,KPNA2,TRIM63,TAF1D,TOMM22,SF3B5,NOL7,DDX42,FEM1A,LRRN1,NEFL,ZNF326,SH2D1A,SSBP1,SF3B6,RPRD1A,PSPC1,FAM118B,CHCHD3,CDK9,NUP35,CAND1,NOP58,HNRNPL,COPE,PPIB,DEPDC1B,EIF3D,PSMD3,STOML2,SERPINH1,CIRBP |
| 6.700e-06 | -11.91 | HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12) | protein interactions | 51144 | 208 | 88 | 19454 | 5460 |
LMBR1L,SEC61B,TAX1BP1,CUL3,RHOB,NTRK3,AKAP1,RAB5A,SSR3,ADRB2,UFL1,COIL,TOMM22,YIPF5,SEC62,SLC25A3,ELOVL1,PHB1,CYB5A,RAB1B,ELK1,EGLN3,RAB5C,LAMP2,DDRGK1,ATG7,AHSA1,RB1CC1,ETFA,KRAS,SAR1B,RAF1,TOP3B,B3GNT2,SOX2,PPP2R1A,TUBA1A,HDAC11,RPN1,CCNF,UQCRC2,SEC61A1,CTSB,COPE,TECR,RAB2A,USP14,UBE2H,NRP1,ATP1A1,RPA3,NCDN,SQSTM1,RTN4,SYVN1,VIPR1,CERS2,ATG16L1,CFTR,CDK7,CDC42,SSR1,GRM2,HSP90B1,METTL14,RPA2,CYC1,MET,AIFM1,HSD17B11,ARF6,LMAN1,DPP4,ATP1B1,LAMP3,ESYT1,SNRNP70,RAB1A,NSDHL,IGF1R,SLC16A1,SRPRB,TNFSF8,PSEN1,UBL4A,APOO,TFRC,FURIN |
| 6.722e-06 | -11.91 | ZBTB16 (zinc finger and BTB domain containing 16) | protein interactions | 7704 | 171 | 75 | 19454 | 5460 |
BCL6,LDOC1,MBD3,HDAC3,NME4,MTDH,EP300,PMAIP1,ACP5,HDAC5,PML,ZBTB42,ANXA7,LSM2,CDK1,CTDSP1,CDKN1A,MX1,SUMO1,MYLIP,TRAF1,ATP6AP2,GSTM4,CBX5,PRKCE,TRIM54,MAP3K3,UBE2I,ZNF655,GNAO1,TRIM27,EIF2S2,DLST,PAFAH1B3,SP1,CCHCR1,TRIM23,TXNIP,SPOP,CCDC85B,AR,CEP70,TTC23,HBEGF,TIMP1,SMN1,IL6,PHF1,VTA1,TOLLIP,ZBTB16,FHL3,ICAM3,RAB27A,TRIM21,RINT1,PLSCR1,TAB2,MTA2,EZH2,TRAF2,EEF1A1,TP53,CDK4,VDR,LYAR,HNRNPL,RB1,SMAD3,SIN3A,DNM2,CRBN,HDAC6,CD81,ZNF24 |
| 6.741e-06 | -11.91 | MOGS (mannosyl-oligosaccharide glucosidase) | protein interactions | 7841 | 188 | 81 | 19454 | 5460 |
ESYT1,AGR2,TRAPPC2L,MED4,HNRNPD,DPP4,NFKB1,ATP5MG,DDRGK1,RAB1B,CAND1,CD1A,POLE3,HSP90AB1,CD274,PHB1,RAP1B,EED,TRAPPC10,CAMK1,POLR2G,CCDC47,FBP1,RAF1,TOP3B,UBL4A,RANBP1,TP53,E2F4,DNAJC25,SOX2,HNRNPF,H3C1,DNAJC30,VDAC1,RIGI,RPL31,SLC39A7,RPS24,PSKH1,NTRK3,IGF2BP1,UBE2H,MYC,CUL3,TOMM40,SLC30A5,SLC25A4,TECR,ESR2,LMBR1L,VDAC2,CYB5R3,B4GALT1,GANAB,PTEN,SEC61B,CTBP1,LMNA,RPA2,METTL14,GRM2,ACACA,HAUS2,NUP62,ATG16L1,FUT8,CDKN1A,EDEM3,CLEC12B,STAU1,FBXW7,RNF11,HSPA5,NCDN,DNAJC3,RPA3,TMEM106B,SQSTM1,RAB5A,EP300 |
| 6.741e-06 | -11.91 | EMC8 (ER membrane protein complex subunit 8) | protein interactions | 10328 | 188 | 81 | 19454 | 5460 |
EMC6,EMC4,PSMD3,KARS1,MOV10,RPL23,RPL24,RHOG,POR,RAC2,HSD17B11,CORO1C,RPL32,PTPN1,WDR44,TMEM237,UQCRH,TMPO,NDUFS8,RPS16,DNAJC1,RPS7,EEF2,ZNF581,MAP1LC3B,DNAJC25,OR4N2,EMC10,CCDC47,RPS23,MTA2,PDHA1,CHMP4C,NDUFS3,RPN1,EMC2,DHX9,TMT1A,RPL31,FKBP8,RPS13,PSEN1,KRAS,HMOX2,CSGALNACT2,ATG101,OST4,ATG3,RPS12,RPS9,SEC61B,RMDN3,RPS3,LMBR1L,S1PR4,UQCRC2,SEC63,ESR2,COPE,MATR3,ATP5F1B,ST7,UQCRC1,CDC42,SEC62,OTULINL,PGRMC1,CYC1,RARS1,SSR1,LMNA,DERL1,GNRH1,SYVN1,MARS1,PXMP2,PHB2,LPAR1,PDHB,EMC1,HSCB |
| 6.748e-06 | -11.91 | LSM6 (LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 11157 | 92 | 46 | 19454 | 5460 |
SNRPD1,SNRPD2,PRMT5,ZMAT2,HERC4,RIT1,MYC,PRPF31,SNRPB,NAPG,COIL,LSM8,SNRPA,POLD2,PRPF4,PPIH,SDCBP,LSM2,WDR77,SF3A1,SNRPN,ZNF511,SNRPD3,LSM5,TOP1,RBM42,ALYREF,DDX23,LSM3,USP15,KRAS,LSM4,DHX16,MEPCE,SNRPG,RIGI,SSRP1,SMN1,LSM14A,HAPSTR1,LSM10,SNRPE,NUPR1,SART3,E2F4,SOX2 |
| 6.754e-06 | -11.91 | VEZT (vezatin, adherens junctions transmembrane protein) | protein interactions | 55591 | 157 | 70 | 19454 | 5460 |
ESYT1,LAMP3,DLK2,CTNNB1,LAMP2,DPP4,TSPAN10,SLC25A46,RAB5C,STX6,TMPO,LMAN1,TLCD4,HNRNPL,ARF6,DNAJC1,ANKRD46,PLEKHO2,HSD17B11,GJA1,RAC2,RAB35,PTPN1,RPN1,TFRC,STIM1,RAB4A,PTRH2,DNAJC25,ACTR1A,SACM1L,FKBP8,KRAS,RAB3B,IGF1R,CYP2C9,TMT1A,NTRK3,MAPRE1,FAS,S100A11,VEZT,RAB2A,GPR17,RAB11A,SEC63,ACTB,RMDN3,SEC61B,LMBR1L,CHRM4,CTNNA1,RPA2,FGFR1,SIGMAR1,SSR1,CDC42,SEC62,OTULINL,ST7,CCL3,STX7,PXMP2,HSCB,FBXW7,SYVN1,RAB9A,DERL1,RAB5A,CXCR4 |
| 6.757e-06 | -11.90 | OCIAD2 (OCIA domain containing 2) | protein interactions | 132299 | 69 | 37 | 19454 | 5460 |
ESR2,PARL,RMND1,ACTB,MGST3,KCNIP3,HPF1,SENP5,FAM199X,CYB5R3,VDAC2,ICAM1,CYP3A43,TOMM40,RAB11A,ATP5MG,MYC,RPL17,VDAC1,SLC25A51,DNAJC30,AKAP1,HADHA,HSPA8,GNG5,TSPAN15,ATP5MK,SFXN1,RAB1A,RPA3,SLC25A3,SLC25A20,RPA2,APOO,CYB5R1,E2F4,SUPT5H |
| 6.759e-06 | -11.90 | cellular respiration | biological process | GO:0045333 | 180 | 81 | 18204 | 5365 |
CYC1,SDHAF4,COX5A,KGD4,ETFB,COX6B2,NDUFB4,UQCRC2,IDH3B,ATP5F1E,IREB2,NDUFS3,IDH1,UCN,ATP5F1D,NDUFB5,TAFAZZIN,NDUFA4,COX8A,NDUFS6,ATP5PF,COX7B2,NDP,OGDHL,SLC25A12,NDUFC2,PDHA1,SDHC,NDUFA2,SLC25A51,NDUFB8,COX6C,ETFA,COX7A1,SLC25A14,UQCRQ,SDHB,FXN,ATP5PO,MDH1,VPS54,COX4I1,COX6A2,IDH3A,NDUFS2,SUCLG2,COX4I2,UQCRH,ATP5MG,COQ10B,IMMP2L,COX7B,STOML2,ATP5PB,UQCC3,DLST,SOD2,COX6B1,UQCRC1,ATP5PD,NDUFB6,COX10,ETFRF1,ATP5F1B,NDUFV2,DLAT,NDUFA1,NDUFS8,NDUFAB1,NDUFB10,ATP5F1A,UQCR11,GPD2,IDH2,SDHAF2,PDHB,NDUFA12,ACO1,NDUFA5,ACO2,NDUFB7 |
| 6.785e-06 | -11.90 | PROTEASOME_BETA_1 | prosite domains | PS00854 | 12 | 11 | 12186 | 3388 |
PSMB10,PSMB9,PSMB7,PSMB5,PSMA4,PSMB6,PSMB11,PSMB2,PSMB1,PSMB3,PSMB4 |
| 6.797e-06 | -11.90 | RAD21 (RAD21 cohesin complex component) | protein interactions | 5885 | 374 | 144 | 19454 | 5460 |
EED,CCAR2,SUMO2,OSBP,EIF2S1,RPS10,KIF3B,HSP90AB1,CCT7,CD1A,RPL6,EIF3D,CSTA,RPL23,LHX2,CCT8,CTTNBP2,FHL3,DNAJB4,HSD17B8,EWSR1,PCNA,GNL1,RBBP7,ARL5B,G3BP1,RFC3,TFG,GOLGA7,PAX6,RAD21,RPS4X,RPS27A,MAX,NAA15,FEN1,RPS7,H1-3,SOX2,TUBA1A,CHMP4C,EZH2,TUBB4B,GTPBP1,MTA2,RPS11,RAN,PARP2,RBBP4,BMP1,ESR2,RABIF,MAD2L2,RPL10,APEX1,USP13,AUH,MYC,MCM4,MCM3,HSD17B1,PRPF31,BRCA1,CCT2,HSP90AA1,RPS5,THBS3,HSPA8,HAND2,FTL,COIL,PSMC1,TOR1AIP2,H1-5,MYL6,RCHY1,ALYREF,SYNCRIP,SSU72,RPS16,RPL35A,MXI1,CITED1,TMPO,CDK9,API5,TPM3,PPM1D,COMMD5,KPNA1,RPS2,TNFRSF14,DHX9,RING1,RPL23A,KPNA2,H3C1,RPL17,MSH6,OLA1,RPS13,MTA3,H2AJ,CCM2,DISC1,ZNF330,CIB2,CTTN,TMSB4X,RPS3,PSPC1,RPS20,PTEN,STX10,ACAT1,CALML5,DAPK3,DEK,RPL22,SMARCA5,RPS17,CFL1,HFE,CDKN2AIP,SERPINB1,ANAPC4,CSTB,SIRT7,RPA3,MEA1,HNRNPH2,PGK1,FBXW7,SMC4,CLU,WFDC5,MBD3,UBA52,CAPN1,PIP5K1A,RPS14,SETD3,GP9,RPA2 |
| 6.809e-06 | -11.90 | INPP5F (inositol polyphosphate-5-phosphatase F) | protein interactions | 22876 | 38 | 24 | 19454 | 5460 |
LAMP2,RAB2A,SFN,RAB5C,RAB11A,YWHAH,LAMP3,YWHAG,LAMTOR1,YWHAZ,STYK1,YWHAB,RAB35,PHF21A,RHOH,RPA2,RAB4A,RPA3,RAB5A,RAB9A,KDM1A,RAB3B,STX7,SACM1L |
| 6.809e-06 | -11.90 | SLC6A5 (solute carrier family 6 member 5) | protein interactions | 9152 | 38 | 24 | 19454 | 5460 |
TM9SF1,SURF4,SDCBP,SIGMAR1,UBAC2,GOLGA5,YIPF3,YIPF5,ATP5PB,TMEM126A,CERS6,GNG5,TBC1D24,STX1A,UFD1,VKORC1L1,CHP1,ATP5F1B,ARL6IP5,DERL2,RETREG3,GPR89A,STARD3NL,RAB35 |
| 6.810e-06 | -11.90 | MicroRNAs in cancer | KEGG pathways | ko05206 | 299 | 139 | 7161 | 2463 |
MIR1-1,PDCD4,FZD3,NOTCH2,MET,SLC45A3,CDK6,VEGFA,MIR135B,MIR206,RAF1,MIR23B,MIR210,MIR223,MIR150,EP300,MIR101-2,HNRNPK,ABCB1,MIR137,BAK1,NFKB1,SLC7A1,MIR30A,MAP2K1,MIR125A,MIR16-2,MIR221,MIR34B,MIR373,MIR195,MIR375,MIRLET7C,MIR9-2,MIR625,PTEN,KRAS,MIR181C,MIR25,MIR126,MIR129-2,MMP9,MIR107,MIR345,PRKCE,SHC1,MIR214,FOXP1,MIR7-2,MIR143,CDKN1A,MIR29A,MIR99A,PRKCB,MIR26B,MIR30E,MIR335,CYP1B1,MIR181D,MIR146A,MIR141,MIR96,PIK3CA,MIRLET7D,MIRLET7I,MIR15A,MIR183,MIR342,MIR152,TP53,BRCA1,MIR330,MIR16-1,MIR30B,MIR449A,MIR17,TGFB2,MIR423,MIR200A,MIR34A,MIR205,MIR10B,TIMP3,MIR34C,MIR615,TNR,UBE2I,MIR1-2,HRAS,MIR29C,MIR200C,EZH2,MIR9-3,MIR23A,MIR21,MIR133B,MYC,MIR101-1,MCL1,CDKN1B,MIR222,PRKCA,MIR324,PIK3R2,MIR363,MIR9-1,MIRLET7G,MIR100,MIR32,IKBKB,CREBBP,MDM2,CRKL,MIR193B,MIR192,MIR155,MIR28,CCND1,MIR145,MIR215,MIRLET7B,MIR194-1,MIR331,MIR30D,EFNA3,DICER1,MIR20A,IGF2BP1,MIR10A,MIR7-1,MIR106B,BMPR2,MIR31,SOS2,DDIT4,ROCK1,MIR194-2,MIR7-3,MIR129-1 |
| 6.810e-06 | -11.90 | MicroRNAs in cancer | KEGG pathways | hsa05206 | 299 | 139 | 7161 | 2463 |
MIR129-2,MMP9,MIR126,FOXP1,MIR214,PRKCE,MIR345,MIR107,SHC1,MIR9-2,MIRLET7C,MIR195,MIR375,KRAS,PTEN,MIR181C,MIR25,MIR625,MIR141,PIK3CA,MIR96,MIR146A,MIR183,MIR342,MIR152,MIR15A,MIRLET7D,MIRLET7I,PRKCB,MIR143,MIR7-2,MIR99A,MIR29A,CDKN1A,MIR181D,MIR26B,MIR335,CYP1B1,MIR30E,MIR23B,RAF1,MIR210,VEGFA,MIR206,MIR135B,MIR150,EP300,MIR223,FZD3,NOTCH2,MET,PDCD4,MIR1-1,CDK6,SLC45A3,MIR221,MIR125A,MIR16-2,MIR373,MIR34B,NFKB1,BAK1,MIR101-2,MIR137,ABCB1,HNRNPK,MAP2K1,MIR30A,SLC7A1,MIR28,MIR155,CCND1,IKBKB,MIR192,MIR193B,CRKL,MDM2,CREBBP,MIRLET7B,MIR215,MIR145,MIR9-1,MIR324,PIK3R2,MIR363,MIRLET7G,MIR32,MIR100,DDIT4,SOS2,ROCK1,MIR194-2,BMPR2,MIR31,MIR7-3,MIR129-1,MIR30D,MIR331,MIR194-1,MIR7-1,MIR10A,IGF2BP1,MIR106B,MIR20A,EFNA3,DICER1,MIR615,MIR29C,HRAS,MIR200C,TNR,MIR1-2,UBE2I,MIR16-1,MIR330,MIR17,MIR449A,MIR30B,BRCA1,TP53,MIR34A,MIR10B,MIR34C,TIMP3,MIR205,MIR423,TGFB2,MIR200A,CDKN1B,MIR222,PRKCA,MIR133B,MYC,MIR9-3,EZH2,MIR21,MIR23A,MCL1,MIR101-1 |
| 6.836e-06 | -11.89 | TM9SF3 (transmembrane 9 superfamily member 3) | protein interactions | 56889 | 124 | 58 | 19454 | 5460 |
P2RY1,ESYT1,ATP1B1,DPP4,ICAM2,EGLN3,OPRL1,NUP35,ARF6,RAB1B,RHOH,RNF128,RAC2,CRELD1,OTULIN,FURIN,PLD3,RPN1,APOO,FAF2,ISG15,RAF1,B3GNT2,TP53,SACM1L,SLC2A8,COX8A,LRRN4CL,NRP1,UBE2H,LAMTOR1,RHOB,AUH,CUL3,COPE,RHOJ,IL2RA,CCNF,TACO1,S1PR4,LMBR1L,RPA2,P2RY12,STOM,CDC42,SLC35E1,CFTR,HSCB,STAU1,SLC25A51,LPAR1,ADRB2,SYVN1,TACR1,AKAP1,SLC35F2,RPA3,TSPAN15 |
| 6.860e-06 | -11.89 | NUMA1 (nuclear mitotic apparatus protein 1) | protein interactions | 4926 | 432 | 163 | 19454 | 5460 |
MCM6,RPS27A,RAD21,ASF1A,NUP42,RUVBL1,EWSR1,RUVBL2,TOP2B,SMARCB1,DCAF8L2,EZH2,PDHA1,NUP153,NCSTN,ASPM,H1-3,LGR4,NAA15,RAF1,LRWD1,NUP35,HSP90AB1,MEAF6,SUMO2,EED,HP1BP3,AGR2,NCK1,CTNNB1,IFI16,BAZ1B,HMGA1,WWP2,LYPLA2,SRM,MCMBP,STAU1,HDAC5,DDX5,EP300,CNDP2,PALS2,APOBEC3C,PSMB7,PCLAF,MAP2K1,ADNP,EMC9,PPP1CB,CNPY3,NUP62,ACTL6A,CBX5,POLR2B,APEX1,SSH3,MATR3,SNRNP40,FBXO22,DYNLL1,TENT5C,TAX1BP1,RBBP4,ZNF22,PARP2,RAN,DLST,HSP90AA1,H1-1,H1-10,BRCA1,RFC5,RNF40,SMARCE1,BTF3,MCM3,MCM4,MYC,PSMA4,RPS13,CAPZA1,H2AC6,EIF3E,MDC1,NUP107,H3C1,KPNA2,ABCE1,NUPR1,CHAMP1,CBX3,CAMK1,NECAP1,CAPZA2,H2AX,ACTR1A,ZMYM4,ZMYM3,CDK9,R3HCC1,ZBTB2,RPL35A,EIF2B2,CDK6,TNKS,H2AZ1,CTDSPL2,ALYREF,SSX2IP,NPR2,TSNAX,BRD3,POLB,H2AC4,SUV39H1,H2AC14,KXD1,MOV10,EIF5B,GTF2I,NUCKS1,FBXW7,HMGB1,DVL2,HELLS,RPA3,BANF1,PML,SIRT7,NBN,MACROH2A2,VPS4B,RPA2,LMNA,H2AC7,WDR83,SUMO1,CCND1,SMURF1,VIRMA,UBA3,NDN,MACROH2A1,RPS20,UBE2I,CCNF,LIG3,ENO1,CDC73,PTTG1,MAPRE1,UBE2H,TXNIP,CHRAC1,DEPDC1B,BRAP,AR,PPP1CC,EMILIN1,SMARCA5,CDC16,CCNB1 |
| 6.975e-06 | -11.87 | OXA1L (OXA1L mitochondrial inner membrane protein) | protein interactions | 5018 | 146 | 66 | 19454 | 5460 |
GFM1,DERL1,RNF113A,VIPR1,EXD2,CXCR4,RPA3,MRPL20,ABCC2,LPAR1,SLC25A51,HSCB,EMC1,MRPL12,MTRES1,GPR35,RPA2,SLC1A1,MRPL13,PTPMT1,EDNRA,CCDC90B,MRPL53,CCNF,TACO1,ESR2,PARL,APLNR,MRPL23,MTM1,ATP5F1B,TOMM40,PMPCA,CUL3,AUH,UBE2H,RIT1,ILK,NRP1,COX8A,NDUFA4,MRPL52,IMMP2L,TNFSF8,METTL15,MGARP,APOO,FAF2,MTCH2,MRPL51,MRPL49,GFM2,PDHA1,GATD3,SDHB,SSBP1,RMND1,EGLN3,MRPL50,ARF6,CTNNB1,MOV10,TMEM70,RHOG,SLC2A1,MRPL18 |
| 6.992e-06 | -11.87 | NACA (nascent polypeptide associated complex subunit alpha) | protein interactions | 4666 | 191 | 82 | 19454 | 5460 |
SUMO2,FZR1,PPP1R18,FUNDC2,MDM2,PBDC1,ZHX1,RPL24,SPP1,PGAM1,WWP2,PIK3R1,ENY2,DDRGK1,BTF3L4,CSNK2A1,COPS5,PPIB,HDAC6,TRIM37,KRAS,HUWE1,H3C1,PTGES3,RAD21,CTNND1,PPP1R12A,RPL31,FAF1,PC,HSD17B10,EWSR1,PRKAG1,NGB,EZH2,NUPR1,RNF8,RAF1,MSX2,ISG15,H2AX,PPP2R1A,JUN,TENT5C,ESR2,RPL10,VIRMA,LRIF1,MORC4,ZNHIT6,CCDC90B,PTEN,FBXW11,H2AZ2,RC3H2,BRCA1,RIT1,UBE2H,SUB1,CUL3,MYC,MCM4,USP14,BTF3,EEF1G,UFL1,IGSF21,SPECC1L,FOS,BAP1,PEBP1,RPA3,SOD1,DDX5,EP300,NMRAL1,HSPA8,METTL14,EMC9,RPA2,UBE2M,HEXIM1 |
| 6.992e-06 | -11.87 | BMH1 (14-3-3 family protein BMH1) | protein interactions | 856924 | 191 | 82 | 19454 | 5460 |
KCTD3,TCP1,DHX15,G6PD,PSME2,EEF1B2,PPP2CB,SEC23A,KRT8,H2AC4,TIAM1,DDX1,PRDX1,PDIA3,BAK1,EDC3,TPM3,NT5C2,GAPDH,LASP1,CNOT7,RUVBL1,TF,RPIA,HNRNPK,FN3KRP,TFG,PRDX4,HSPD1,ZYX,PSME1,PABPC1,PDIA6,IGF1R,HSPA13,BZW2,NME1,PPME1,CRKL,TBC1D4,TXNRD1,CDK4,ACO1,PSMB9,EEF1A1,ACTN4,TUBA1A,EEF2,ATP5F1B,TUBB,TXNDC12,GMDS,ACTB,MAT2B,IDE,STUB1,BAD,CTTN,ALG2,CSNK2B,RCBTB1,SERPINB1,RBM7,MAT2A,CTSD,ATP5F1A,GMPS,MCM3,EEF1G,PFKFB2,FBXW7,SMC4,HSPA5,SKP1,HSPA8,TXNL1,EXOSC4,PRDX6,HSP90B1,KLC2,ACACA,CSNK1A1 |
| 7.002e-06 | -11.87 | SRP14 (signal recognition particle 14) | protein interactions | 6727 | 353 | 137 | 19454 | 5460 |
MRPS9,PRNP,FZR1,CAND1,SURF6,CDC5L,CDK9,DKC1,MDM2,DNAJB2,TLE1,COPS5,MPHOSPH10,SNRNP70,RPS2,METTL18,RPL3,MRPS18B,SEPTIN7,VRK1,MRPS33,HUWE1,PAK1IP1,MEPCE,MRPS18C,DDX42,CASK,SRP72,NUPR1,EIF4A3,RPS3,CCNF,PTEN,SRP54,PRKRA,MRPS21,ZNF622,RPL22,SEC63,RPF2,CDC16,DNAJC8,RC3H2,SPOP,DNAJC19,UBE2H,NRP1,ANAPC4,BAP1,RPA3,PPM1G,RAB9A,SQSTM1,HMGB1,FBXW7,AATF,ATG16L1,CFTR,RPA2,MRPS34,P3H1,WTAP,RPL26L1,RPLP0,HEXIM1,PHB1,FOLR1,RPLP2,RPLP1,HP1BP3,EED,SNRPA1,LYAR,MRPS35,WWP2,RPL6,PRPF19,LAMP2,DDRGK1,TRA2A,NGDN,ATG7,MRPS26,POU5F1,TMEM87A,MRPS11,GNL1,TNF,H1-6,PSMA1,KRAS,RPL28,UBE2A,RPS4X,B3GNT2,RAF1,ANP32A,TOP3B,MAK16,SOX2,GLE1,EZH2,CYB5B,RPS23,ZNF22,ANAPC2,SNRPD1,SNRPD2,ZCCHC7,RPL35,RPF1,RPL10,RPL19,ESR2,KBTBD6,CUL3,MYC,USP13,ZNF668,BTF3,H2AZ2,FTSJ3,MRPS25,NSA2,RIT1,ICAM1,DDX5,NSFL1C,GPC1,STAU1,UFL1,MRPS7,G3BP2,ASB3,GPC4,PIH1D1,KLC2 |
| 7.038e-06 | -11.86 | SURF4 (surfeit 4) | protein interactions | 6836 | 174 | 76 | 19454 | 5460 |
FGFR1OP2,CUL3,DNAJC5,DNAJC8,ARHGAP19,NRP1,CCNF,LMBR1L,SYNGR1,GPR173,SEC61B,SLC1A1,SNRNP40,VIRMA,APEX1,ATG16L1,SEC62,DIO3,CFTR,RPA2,ATP5PO,STOM,SSR1,GPR35,UBAC2,FAM8A1,CAV2,RPA3,TSPAN15,TMEM106B,SYVN1,SF3B1,VIPR1,RAB5A,AKAP1,SLC35F2,STAU1,SAP18,COIL,HSPA5,MOV10,DPP4,RAB5C,DDRGK1,DEGS1,SLC2A1,RB1CC1,PEX3,DNAJC7,THOC2,PHB1,SRSF1,FBXO32,HP1BP3,DNAJC1,STX6,SERINC3,NOP9,UBL4A,TP53,DNAJC25,NCSTN,YIPF3,LGR4,EZH2,STIM1,RPN1,KDELR1,PLD3,ATP5PF,SFXN1,LPAR2,SEPTIN7,ABCE1,SRSF7,RIGI |
| 7.075e-06 | -11.86 | IPO9 (importin 9) | protein interactions | 55705 | 214 | 90 | 19454 | 5460 |
H2AZ1,SRP14,ARF6,VTI1B,CAND1,PRNP,CDC5L,H2AC4,RAB1A,MEPCE,RIGI,H2AJ,COMTD1,CHRM3,IPO8,H2AX,SIGLECL1,DISC1,ADORA3,CCNF,CHRM4,ZNF330,CTNNA1,PPP2R5E,PTPMT1,GNPDA1,RPGRIP1L,VIRMA,SMARCA5,SLC25A1,FBXO7,ST13,TUFM,BAP1,RPA3,IDH3A,SYVN1,MTDH,FBXW7,HSPA5,ATG16L1,CDC42,CFTR,LMNA,RPA2,STOM,GRM2,HSP90B1,MACROH2A2,FBXO32,KRT8,RPS10,CEP19,XPO1,YWHAG,YWHAH,DDRGK1,RHOG,YWHAB,EFNB1,COX8A,PSMA1,KRAS,B3GNT2,RAF1,RANBP1,PPP2R1A,FAF2,RPN1,H2BC1,LMBR1L,S1PR4,BAD,RAN,POLR3B,TNPO3,USP5,MYC,SFN,CUL3,YWHAZ,DCAF4,HSPA8,HADHA,EP300,RAB5A,SEC62,CTBP1,KLC2,HEXB |
| 7.114e-06 | -11.85 | Cytokine Signaling in Immune system | REACTOME pathways | R-HSA-1280215 | 756 | 292 | 10285 | 3229 |
FASLG,EDA2R,PSMA5,IFNA2,FGF23,EIF4E,PPP2R5E,YES1,PSMB3,PEBP1,IFNA13,IFNG,YWHAB,STX1A,CCL5,TRIM34,PPP2R5A,RAP1B,STAT2,TNFRSF14,IL10,WDR83,TRIM3,UBA52,CNTFR,EIF4E3,IL7,FRS3,DUSP9,KPNA1,SRC,PIAS1,FGF10,TNFSF15,YWHAZ,IL5,LAMTOR2,KIT,TRIM8,IL15RA,IL34,PSMA6,MCL1,RNASEL,MAP3K14,FGF16,CAMK2G,IL12A,IL2RB,IFNA10,VWF,UBE2N,IRF6,TRIM46,TP53,PSMC3,IFNAR1,TOLLIP,TRAF2,CD86,CSH1,RPS27A,EGR1,IL1RAP,XAF1,PTPN1,SPRED1,TRIM6,PSMB4,IFI27,SEM1,RIGI,VEGFA,DUSP1,IRF9,PSMB10,B2M,NDN,PSMC5,IL2,FBXW11,RHOU,IL22,BRAP,CSK,DLG4,INPPL1,PSMB7,IFI35,SAMHD1,PSMD3,H3C1,CCL19,TRIM62,PIK3R1,PSMB5,PSMA3,FOS,CXCL1,IRF2,TIMP1,IL1R2,TRIM35,IL18BP,HSPA8,SOCS5,CBL,CXCL8,PPP5C,SKP1,CD40LG,UBA3,IL12B,GHR,CD80,FGF17,TRIM68,PSMD7,MX1,PPM1B,STAT1,NUP107,RAP1A,EIF4A3,CD4,PIK3R3,CDKN1A,FGF7,KPNA2,LTB,MYC,TRIM29,BATF,EIF4A2,TRIM22,MT2A,NUP35,NEFL,DUSP10,SQSTM1,PSME2,HBEGF,TRIM5,PSMD6,HSP90B1,SPRED2,TRIM10,MAP3K3,IFNB1,MYD88,IRAK4,LTBR,PAQR3,NFKB1,MET,JUNB,IL1A,SPTAN1,IFI6,IL15,IL2RG,PIK3R2,OAS1,TRIM21,MX2,SOCS3,TAB1,BIRC5,ISG15,CISH,GH1,FGF1,TNFSF12,DUSP6,KRAS,MAP2K1,TRIM45,FGF22,SYK,IL23A,PELI3,RAF1,CCL3,PSMD10,IRF1,CD36,IL13,CCND1,MMP9,PML,BCL6,CCR2,STAT6,HRAS,IFIT2,PPP2CB,IRF7,UBE2V1,NUP42,PSMB2,PSMD1,AKT1,PEA15,SUMO1,HSP90AA1,PIK3CA,IL20RB,IL18,TAB2,ISG20,LAMTOR3,MAP2K6,CCR5,CUL3,PSMC1,PSMA1,TNFSF13,OSM,IL3,IFNGR1,PSMD4,PHB1,OPRM1,SOCS2,IKBKB,RASGRP3,SHC1,BCL2L1,NUP62,CCL11,PSMA4,CCL20,FGFR1,PSMB11,PSMB6,IL17F,PSMA2,IL4,JAK2,TNFRSF1B,PSMB1,NUP50,CRKL,CCL2,IL6,SOX2,CCR1,PSMC4,IRF4,PSMD14,PTPN11,CD40,RSAD2,PPP2R1A,PELI1,TNF,STAT5A,UBB,LTA,RAG1,SPTBN1,ANGPT1,PSME1,PRL,ICAM1,IRF8,SHC3,TNFRSF9,IL6ST,TNFSF18,NUP37,EIF2AK2,CSF2,FCGR1A,JAK1,TNFSF8,IRF3,BST2,PSMD12,COL1A2,MAP3K11,IL1B,EIF4E2,UBE2M,BIRC2,CXCL10,FGF3,TRAF6,IL2RA,NUP153,PSMB9,TRIM26 |
| 7.134e-06 | -11.85 | secretory vesicle | cellular component | GO:0099503 | 1076 | 377 | 19108 | 5553 |
ORMDL3,SYNGR3,EEF1A1,NPC2,HP,SYNDIG1,DSN1,TUBB,TMEM179B,CD59,SYP,TRIM36,IGF1,LGALS3,BPIFA2,OLA1,AGA,JUP,FGR,CPE,RAP2C,LYZL6,GHRL,ACTN4,CLU,ENPP4,SERPINB6,VAMP1,TCP1,MOXD1,LHFPL2,OPRK1,CAB39,SRI,ATP6V1G2,TMT1A,XRCC5,SDCBP,RAB9B,HSP90AB1,RAB3D,RAB6A,ACTR1B,TREML1,CAND1,NPY,PSMD1,HSPD1,RARRES2,DYNLL1,CD58,STX10,ADRB2,RAB11B,PSMA2,DNAJC5,FCGR2A,GZMK,RAB37,PNP,TMEM30A,GDI2,PLCB2,KLK9,GCA,ABHD2,PRRT1,SLC35F1,IZUMO1,TNFAIP6,SYNGR1,HEBP2,GNAI2,KIT,FABP5,BRI3,PCYOX1L,RAB31,TOR4A,APEH,VAMP7,SLPI,CALML5,SEPTIN6,LAMTOR2,RACGAP1,SNAP91,COPS5,RAB13,GSTP1,ATG7,MMP9,GAD2,FCER1G,BACE1,RAB3A,STXBP1,STBD1,ATP8A1,KCNJ11,RAP1B,CPNE1,PSEN2,HEXA,LAMP5,PSMA5,RND2,CD9,STX7,PICALM,PRDX6,PSEN1,FAF2,RAB14,BST2,HEXB,MIF,LAMTOR3,SCG3,SEMA4C,LAMP2,GTPBP2,TEX264,ZNRF1,FTL,PSMB1,ATP6V1C1,VEGFA,COTL1,CCT2,SFTPA1,RETN,LACRT,CST3,SLC35G2,EEF2,ANXA7,EXOC3,PSMC3,COMMD9,GRIA1,KLK6,CXCL1,MT3,B4GALT1,NCSTN,CYSTM1,RAB5A,CD46,DBH,GLIPR1,PROS1,SRP14,PAFAH1B2,DNAJC3,SERPINA3,PICK1,TLR2,PSMD14,NDUFC2,TGFB3,RAB3B,DISC1,TICAM2,CARTPT,HCRT,PRDX4,RAB40AL,TMEM190,SVOP,PYCARD,ACTR2,ARMC8,ANXA4,VAMP2,ROGDI,SNX10,GABRA2,KLK5,VDAC2,CYB5R3,CD36,RAB18,VTI1B,FGL2,ICA1,NPPC,CYRIB,SYNGR2,CAV2,SELL,PRSS37,COPS4,SYPL1,SERPINA1,ILF2,RAP1A,HMGB1,SYT4,FAM3C,PLAC8,LYZL4,CAMP,PSMB7,SLC32A1,CAPN1,RABAC1,SLC30A5,TMSB4X,LYZ,GGH,CTSB,CALR,CMA1,SRGN,MME,AP1M1,FCAR,TMX3,ATP6V1D,PDE4B,PCSK2,STX11,SURF4,CHI3L1,RAB4A,SLC4A8,CD47,VWF,TNFRSF1B,PPIA,SFTPC,PSMD3,NUDT1,ROCK1,PAK2,CYB5R1,S100A8,KLK3,GOLGA7,PLEKHO2,CTSC,TOM1,PSMD7,LAMTOR1,SYNPR,TIMP3,ATP6V1G1,PADI2,SIGLEC5,TBC1D10C,RAB27A,HILPDA,PGAM1,NTF4,STX1A,SERPINB10,YPEL5,VEGFC,CDC37L1,SNAPIN,IQSEC1,ATP6AP2,SERPINA5,PGRMC1,RAB5C,SYN3,CSTB,SNAP23,LGI3,TTR,PSMD12,APH1A,SCAMP5,LAMP3,PATE4,STX12,HSPA8,PPFIA2,NFKB1,SYNGR4,CSNK2B,CTSD,TMED9,ALB,TUBB4B,CTNNA1,BCL2L1,MAGED2,DNASE1L1,SERPINB1,IL1B,TOLLIP,LILRA3,RAB8B,SNAP29,CHGA,SERPINI1,VAMP8,CAV1,VEZT,PYGB,SLC2A3,CDC42,CFAP119,STOM,PDYN,TMBIM1,DEGS1,TF,RAP2B,NME2,RHOG,TSSK1B,BORCS5,HUWE1,SPACDR,CTSA,RAB2A,SLC18B1,STX6,MTMR2,SCG2,CPLX3,ADRB1,CCT8,HBB,ATP6V1A,OLR1,SPTAN1,CRHBP,COMMD3,B2M,PLG,PDAP1,PPFIA3,PPT1,ATP6V1E2,TIMP1,NEU1,SLC17A5,S100A11,SST,CXCR1,VAMP3,ITGAV,CYB561,CMTM6,GABBR1,TMEM95,ACTL9,PRCP,HMOX2,DPEP3,TYROBP,STX16,CD63,CLCA1,FTH1,SCG5,RAB3C,SVIP,RNASET2,PGM1,SYT2,HSP90AA1,IDH1,TRAPPC1,SELENOP,PSMD6,SNAP25,TRAPPC4,SV2B,DLG4,CD14,TGFB2,CTTNBP2 |
| 7.143e-06 | -11.85 | MARCHF8 (membrane associated ring-CH-type finger 8) | protein interactions | 220972 | 52 | 30 | 19454 | 5460 |
VAMP7,CGAS,BST2,FA2H,CD274,PTK7,WDR6,CD86,FUBP3,CA2,UBE2H,UBE2D1,FAS,HNRNPA1,HMOX2,RAB5C,IL1RAP,UBE2D3,B2M,HNRNPK,HAPSTR1,CYB5B,VAMP2,ABCB1,TFRC,EXOSC3,PGM1,CCDC47,GOSR2,NOTCH2 |
| 7.165e-06 | -11.85 | PPP4R2 (protein phosphatase 4 regulatory subunit 2) | protein interactions | 151987 | 108 | 52 | 19454 | 5460 |
CDC5L,SNRPA1,FZR1,LCMT1,DSTN,IGBP1,USP15,UBXN10,FAM133B,PRPF19,MSH6,MCM6,KPNA2,TSSC4,PSMA1,PPME1,SF3B5,RPS11,PPP4C,TRAPPC13,METTL15,DHX38,RAP1A,SUPT5H,COMTD1,MARCKSL1,SNRPB2,DYRK1A,MATR3,SNRPD2,SF3B4,MIDEAS,SF3B6,STK24,DNAJC8,DRAP1,MCM4,CUTA,WDR55,SMC4,NUCKS1,TRA2B,RNF113A,NUBP2,SF3B1,INPPL1,UBE2M,CDK1,RPA2,PAAF1,SF3A1,SYK |
| 7.165e-06 | -11.85 | TSSC4 (tumor suppressing subtransferable candidate 4) | protein interactions | 10078 | 108 | 52 | 19454 | 5460 |
SNRPB,MYC,IDE,TRAF1,TAB1,SNRNP40,SNRPD2,AP2M1,SNRPD1,RSRC1,MFAP1,TFIP11,LSM2,WDR83,ATG16L1,TXNL4A,SNRPN,TRIM52,FTL,EIF5B,RBM22,CWF19L1,SLU7,NCDN,KPNA1,DDX23,ECD,INSYN1,TPM3,PRPF19,ZCCHC10,EGLN3,CWC15,CDC5L,SPTAN1,SNRPD3,BUD31,GPBP1L1,MTA2,SNRPE,IK,ESS2,TRAF2,CD2BP2,RAF1,DHX38,SNRPG,CDC40,TSSC4,RUVBL1,RUVBL2,EMC2 |
| 7.222e-06 | -11.84 | regulation of protein kinase activity | biological process | GO:0045859 | 469 | 182 | 18204 | 5365 |
FGFR1,MIR26B,PTPRQ,PTPN1,GHR,SRC,RAP2C,ANGPT1,HEXIM1,PHB2,PIK3CG,THY1,TLR4,LEP,DLG4,TRIM27,CCNY,TAF7,DIPK2A,TAB2,TCIM,IFNG,PDCD4,CACUL1,MIR34A,MIR15A,CDKN1B,MIR711,NTRK3,MIR218-1,PPARG,CCNA2,CCNB1,CAMK1,PAQR3,IL34,IL23A,CEP85,UBASH3B,EZH2,FGF16,CORO1C,RALB,HEXIM2,CD40,RGS2,FBXW7,BCCIP,CAB39,STK11,PKIA,PYCARD,HRAS,DUSP10,STK38,CAMK2N1,ACTB,MAP3K11,TNF,ADIPOQ,MIR24-1,DUSP22,CDKN2C,TRAF2,RAP1A,SERTAD1,DUSP1,PHB1,RPS3,GSKIP,CCNH,CAMK2N2,CCNF,TRAF6,GADD45A,CCL19,DIRAS1,TRIB1,XRCC5,PSMD10,NHERF1,CHI3L1,CDKN1A,TESK1,PIH1D1,RB1,STRADB,PSRC1,INPP5K,ERRFI1,TPD52L1,SPRY1,SOCS4,PRNP,MAP3K12,HSP90AA1,CDK5R1,CCL5,YWHAG,TLR3,EPHA4,FGR,IL12B,ERP29,FERMT2,RTRAF,TOM1L1,CD86,PPIA,GNAQ,HSPB1,DUSP19,PKIG,EMP2,SOCS5,SMG8,RGCC,IL4,SFN,CDKN3,LCP2,MIR21,CD4,LILRB4,CAV1,TAB1,CDKN2D,HSP90AB1,AGAP2,PRKAG1,CAV3,RAP2B,PTPN22,AKT1,TNFSF15,IL1B,TLR6,CCR7,PROX1,ADRB2,IGF1,DBNDD1,PDCD10,SPRED1,MAP2K3,DUSP3,TGFB2,CHP1,GH1,TXN,GSTP1,HYAL2,MT3,CCNI,CCND3,MIR20A,KIT,CBL,CDK12,CCND1,PAK2,TGFBR2,SLC8A1,SOD1,DIRAS2,CARTPT,DLG3,JAK2,PTEN,MMD,TSG101,FGF1,PKIB,MACROH2A1,LRP6,DVL2,CDK5RAP3,MAP2K1,HGS,DEFB114,FCGR1A,DIRAS3 |
| 7.246e-06 | -11.84 | EIF3E (eukaryotic translation initiation factor 3 subunit E) | protein interactions | 3646 | 249 | 102 | 19454 | 5460 |
HEXIM1,UBE2M,PTPN22,RPA2,CFTR,EIF3J,ATG16L1,RGS2,AATF,EIF4E,FBXW7,PML,SIRT7,RPA3,SOD1,BAP1,UBE2H,RC3H2,EIF3G,VIRMA,SMURF1,RPS20,RPS12,CSNK2B,TRIM27,METAP2,CCNF,PSPC1,RPS3,NUPR1,SRP72,TP53,RPSA,MEPCE,TRIM63,EIF4EBP2,HUWE1,HAPSTR1,ABCE1,RPS2,H2AC4,GPRASP2,CD81,CSNK2A1,EMC4,RBM42,TMPO,RPS16,FZR1,PIH1D1,EIF4B,SUPT4H1,G3BP2,ZDHHC17,SAP18,STAU1,UFL1,EIF1B,EP300,RAB5A,RPS28,RIT1,ICAM1,BRCA1,ISCA2,PRPF31,CUL3,COPS7A,MYC,PRRC2A,RPL10,ESR2,EIF4A2,RPS9,EIF3K,CMTR1,RPS23,GPBP1L1,POLR2C,RPS11,CHMP4C,EZH2,VPS33A,ANP32A,UTP25,PSMD12,MAPK1IP1L,KRAS,G3BP1,GPAA1,DRG1,SMAD9,AGR2,CTNNB1,DDRGK1,EIF3D,XPO1,WWP2,COPS7B,RPS10,OCRL,COPS2 |
| 7.271e-06 | -11.83 | EVC2 (EvC ciliary complex subunit 2) | protein interactions | 132884 | 87 | 44 | 19454 | 5460 |
PLD3,ACTR2,STIM1,RPN1,NUDCD3,LBR,MACO1,CCDC47,PREB,FKBP8,SRPRB,BAG2,EMC2,SEC11A,NSDHL,SMAD9,DCAF11,DNAJC7,ESYT1,POR,DDRGK1,YWHAH,DHRS7,TMEM199,STX5,GYS1,CAMLG,PTPN1,SRPRA,ISOC1,ST7,RABL3,UNC45A,SPCS2,TTC1,BANF1,SCFD1,SPCS3,HMOX2,VEZT,SEC63,ATP6AP2,STUB1,LMBR1L |
| 7.352e-06 | -11.82 | BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B) | protein interactions | 701 | 177 | 77 | 19454 | 5460 |
SOCS2,PELI1,KRAS,TRIM37,SEMA4C,BAG2,ZYX,CERK,SKA3,PNMA2,MAD2L1BP,PPP2R1A,ANAPC13,EEF2,CD14,COMTD1,CENPM,TP53,EGLN3,MDM2,CDC5L,MXI1,NUF2,FZR1,NKAP,KRT8,PSMB5,CDC23,MED4,DNAJC7,HSPB1,SKIC8,XPO1,PPP2R5A,CDC26,NDC80,UGP2,KDM1A,HDAC3,CYFIP2,FBXW7,MIS12,ANAPC16,ATP5IF1,HSPA8,PSMA3,SNCG,RPA3,NEK2,CCNA2,SUMO1,CDC20,MAD2L1,DYRK1A,BUB3,PSMD6,TUBB,GANAB,PPP2R5E,PHF21A,ANAPC2,PSMA6,ANAPC4,PTTG1,RIT1,CCT2,S100A11,FBXO7,ANAPC15,TYW3,RPL39,OST4,NAA50,DSN1,CDC16,PSMA4,CUL3 |
| 7.383e-06 | -11.82 | Ribosomal scanning and start codon recognition | REACTOME pathways | R-HSA-72702 | 61 | 36 | 10285 | 3229 |
EIF3G,RPS3,EIF2S2,EIF3E,EIF4B,RPS14,EIF4E,EIF3K,EIF3J,RPS20,RPSA,FAU,RPS24,EIF3D,EIF4A2,RPS16,RPS11,RPS29,EIF2S1,RPS23,RPS2,RPS12,RPS4X,EIF4H,RPS27A,RPS9,RPS13,RPS5,RPS15,RPS17,RPS28,RPS10,EIF1AX,RPS27L,RPS7,RPS26 |
| 7.393e-06 | -11.81 | SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit) | protein interactions | 11198 | 408 | 155 | 19454 | 5460 |
POLB,H2AC4,CHCHD1,CDK12,EMX2,BRD3,CALR,MOV10,DPP4,CSNK2A1,CD81,CAND1,TOP1,CDK9,DKC1,ZBTB2,H2AZ1,RCHY1,CBX3,IK,NUPR1,FURIN,H2AJ,TP53,H2AX,EEF1A1,H3C1,VRK1,POLL,RNF20,MSH6,SNIP1,GLUL,HAPSTR1,ABCE1,POC1B,RING1,DHX9,RC3H2,UBE2H,SMARCA5,CIAO1,AR,PPP1CC,USP14,RHOJ,CEP97,VIRMA,SRPK2,CCNF,LIG3,ZNF330,FGFBP1,CSNK2B,MACROH2A1,TRIM24,H2BC11,RPA2,RNF146,HEXIM1,ACACA,MACROH2A2,ATG16L1,SF3A1,CDK7,FTH1,CFTR,NF2,FBXW7,HMGB1,TOMM20,HSPA5,BAP1,PPM1G,RPA3,NLE1,ELOF1,MTDH,DDX23,PPM1B,MED4,IFI16,XPO1,WDR11,DDRGK1,HNRNPL,SUMO2,COMMD6,CNTROB,MACROD1,HMG20A,DHX15,EED,EZH2,PDHA1,H2BC1,CHMP4C,SMARCB1,AAMP,RHOBTB1,B3GNT2,TOP3B,RAF1,SUPT5H,E2F4,DHX38,NCSTN,ISG15,SOX2,GTF2E2,KRAS,HMGN4,VDAC1,SSRP1,GOLGA7,NEK9,RPL31,TOP2B,PABPC1,EWSR1,FYTTD1,FBXW11,RHOB,DCAF4,BRCA1,ICAM1,RIT1,DNAJB6,MYC,CUL3,SFN,SMARCE1,BTF3,MCM3,MCM4,SNRNP40,RPL10,IRF2,SNRPD1,SNRPD2,USP39,APOBEC3C,MTF1,H2BW1,ACTL6A,RND2,UFL1,STAU1,SAP18,COIL,SNRPA,XRCC5,HSPA8,COMMD2,EP300 |
| 7.393e-06 | -11.81 | PRPF40A (pre-mRNA processing factor 40 homolog A) | protein interactions | 55660 | 408 | 155 | 19454 | 5460 |
WBP11,SERPINB9,H2AJ,TAF2,NUPR1,DDX42,EMC2,DHX9,PPP1R12A,SNIP1,ZNF451,MEPCE,GALNT2,RIGI,VPS16,ERLEC1,WASL,HNRNPK,COPS5,CSNK2A1,PRSS12,PPIL4,GAPDH,CDK12,AKAP8L,BRD3,TSNAX,TCEAL9,SMAD4,SNRNP70,SYNCRIP,RCHY1,CDK9,ZBTB2,RPL35A,NKAP,TOP1,GABRA1,DDIT4L,SF3A1,RPLP0,HECTD1,TOX4,SDCBP,RPA2,RNF113A,DDX46,BAP1,RPA3,SIRT7,PML,PIAS1,NPM3,UBE2K,IL1RAP,NUCKS1,RPL4,AR,NONO,PPP1CC,SMARCA5,VPS39,CAP2,PPIG,UBE2H,MECP2,SPOP,RBMX2,SYT2,GSK3A,UBE2I,PSPC1,PELP1,CCNF,EIF4A3,TUBA1B,CTTN,PPP1R10,DEK,SRPK2,VIRMA,IFI6,RPL13A,NCSTN,B3GNT2,FASLG,RAF1,EMC10,AAMP,SKA3,NFKBIL1,CHMP4C,EWSR1,PICK1,FAM76B,SREK1IP1,SRSF7,SSRP1,G3BP1,KRAS,RBBP7,HNRNPF,HNRNPA1,YWHAG,TRA2A,DDRGK1,IFI16,FRA10AC1,ZCCHC10,ANKRD50,HSPB1,DDX23,EED,ZHX1,MAP1LC3A,FOLR1,SRSF1,SRSF10,NUP35,WIF1,CCT7,NUF2,DHX15,SNRPA1,DAAM1,MFAP1,NUFIP2,TRMT112,SF3B1,DDX5,EP300,SNRPA,DDX39B,NKAPD1,SAP18,CYFIP2,UFL1,STAU1,SMARCE1,SNRPB,CPSF2,MYC,HNRNPC,CFAP20,CUL3,RIT1,CCT2,H1-10,RPL37A,SF3B4,RPS9,CPSF1,SNRPB2,ESR2,SNRNP40 |
| 7.409e-06 | -11.81 | The citric acid (TCA) cycle and respiratory electron transport | REACTOME pathways | R-HSA-1428517 | 158 | 76 | 10285 | 3229 |
NDUFAF2,PDHA1,ACO2,ATP5F1D,COX5A,ATP5F1A,COX4I1,LDHAL6B,TACO1,NDUFV2,NDUFA5,ATP5F1E,ATP5F1B,NDUFB4,NDUFS6,COX14,GLO1,NDUFB6,TMEM126B,ATP5PD,SLC25A27,UQCRC1,COX6B1,NDUFA4,SUCLG2,IDH3A,ETFB,UQCR11,NDUFC2,UQCRQ,COX16,ATP5PO,DLAT,ATP5PB,ATP5MG,SDHC,PDHB,IDH3B,UQCRC2,COX20,NDUFAF3,NDUFS2,NDUFB10,CYC1,COX8A,NDUFB7,SLC25A14,COX11,ETFA,ATP5MC1,UQCRH,IDH2,NDUFB8,ATP5PF,NDUFB5,NDUFAF6,NDUFA2,DLST,COX7B,PDP2,NDUFAF4,COQ10B,UCP2,LDHA,LDHB,MPC1,NDUFS8,NDUFA12,NDUFAB1,ATP5MC3,COX6C,SDHB,NDUFA1,NDUFS3,TIMMDC1,SLC16A1 |
| 7.433e-06 | -11.81 | TTC1 (tetratricopeptide repeat domain 1) | protein interactions | 7265 | 149 | 67 | 19454 | 5460 |
SH3BP4,GNAI2,SULT1A3,SRXN1,CCNF,ANAPC2,LAMTOR1,BICD2,FIS1,HSP90AA1,DNAJB6,CARS1,KPNA6,BAG3,KDM1A,UCHL3,TOMM20,RNF41,TUSC2,BAP1,PPM1G,THOC3,RPA3,SCN1B,HSPA8,AKAP1,RPA2,VAPB,NDE1,TOMM22,SHMT1,EIF3J,FZR1,PRNP,OSBP,LMAN1,HRAS,THOC2,PPP2CB,XPO5,DSTN,GANC,SEC23A,SPP1,KCNJ10,DNAJC7,XPO1,GTF2E1,DYNC1I1,UFM1,SRPRB,PDE2A,AHCYL1,SPSB1,SIKE1,BAG2,PDIA6,GLE1,UBE2B,ZRANB2,GNAQ,KBTBD4,MTCH2,TUBA1A,CYB5R1,GFPT1,ACTR1A |
| 7.433e-06 | -11.81 | PLD6 (phospholipase D family member 6) | protein interactions | 201164 | 149 | 67 | 19454 | 5460 |
CNDP2,CHPF2,EIF2B3,SEC22B,JMJD8,HSPA5,TOMM20,ATAD1,PHB2,EMC1,AKAP1,GFM1,HNRNPH2,EXD2,MME,CYB5D2,ATP2C1,MAIP1,UGDH,SERPINH1,THTPA,GTPBP2,CHPF,SFN,PSMB2,TRIM32,SEC63,ABHD12,MGST3,EIF4A2,GANAB,GGT7,LRRC1,PIGK,CYRIB,PLD3,GNAI3,GFM2,ACTR2,UCK2,TUBB4B,DDX39A,GFPT1,MTCH2,IMPA2,LRP3,ERLEC1,USP30,ERP29,PRPSAP1,SCPEP1,PEX3,ESYT1,TMEM11,HM13,RAB5C,SLC25A46,MICB,OS9,GNPAT,RGP1,DIPK2A,ARL10,PHB1,COQ8A,HACD3,SRPRA |
| 7.433e-06 | -11.81 | CDC25A (cell division cycle 25A) | protein interactions | 993 | 149 | 67 | 19454 | 5460 |
SRC,ROCK1,CDC20,UBB,NFKBIB,FAM91A1,DNAJC10,FBXW11,YWHAZ,DCAF4,AR,H2BC9,FAM193B,CCNB1,SFN,CUL3,CDKN3,NFYA,CREBBP,LMO2,SKP1,FABP4,MCMBP,HDAC3,GTF2I,EP300,CCNI,PPM1G,CSNK1A1,KCTD12,CDK1,CCNA2,CDKN1A,FTH1,POLR1D,EGLN3,NAA11,FZR1,LDLR,MTAP,HRAS,WDR6,SMAD3,YWHAB,WDR11,HCRT,YWHAG,XPO1,YWHAH,USP3,PDIA3,CALR,HMGA1,AHCYL1,MCM6,VAMP8,RBBP7,FBXO11,CDK5,PIK3CG,ALPL,MTA2,PNMA2,HDAC11,EEF1A1,E2F4,RAF1 |
| 7.451e-06 | -11.81 | GEMIN5 (gem nuclear organelle associated protein 5) | protein interactions | 25929 | 255 | 104 | 19454 | 5460 |
MYC,CUL3,SNRPB,FBXW11,BRCA1,LSM14B,S100A6,SNRPD1,SNRPD2,PSMD6,RBBP4,MAD2L1,PSMB6,SNRPB2,ESR2,ACTL6A,PPP1CB,ETF1,EIF4B,PIH1D1,CNDP2,SNRPA,CD40,XRCC5,NPTN,MCMBP,STAU1,PSMD3,DDRGK1,CTNNB1,PSMD10,MED4,RB1CC1,DDX1,THOC2,EED,BRD9,HNRNPL,SNRPA1,SNRPD3,DYNC1I2,SUMO2,DHX15,TOP3B,LGR4,SNRPE,OTULIN,THNSL1,EWSR1,RUVBL2,RUVBL1,PFDN1,SSRP1,GEMIN8,PEA15,UBE2H,PSPC1,CCNF,SRP54,RPS20,TXN,ADRM1,VIRMA,ATG16L1,SF3A1,SNRPN,CDK7,ELP3,RPA2,BAP1,DDX46,RPA3,SIRT7,PRKCB,CLK1,RNF113A,KDM1A,EIF4E,CXXC1,NFKB1,MOV10,COPS5,HDAC6,TPM3,SNRNP70,MAP4,USP15,TSNAX,PTPN1,EEF1AKMT3,RPS16,TOP1,THOC1,RRM1,COMTD1,UBL4A,TP53,MAP1LC3B,CDK8,GEMIN7,PSME1,PTGES3,SNRPG,SMN1 |
| 7.453e-06 | -11.81 | GOSR2 (golgi SNAP receptor complex member 2) | protein interactions | 9570 | 127 | 59 | 19454 | 5460 |
VAMP5,TM4SF19,CSGALNACT2,CYB561,RIC3,TMEM106C,RIT1,NAPA,MFSD14B,SCFD1,ELOVL4,ARF1,SEC61B,DKK3,RETREG3,TAX1BP1,SEC22B,BET1,CHST7,BLCAP,ST7,CDC42,SEC62,OTULINL,TMEM106A,RND2,USE1,PTP4A2,LMNA,RPA2,JAGN1,DERL1,BET1L,LPAR1,GOSR1,EMC1,STX7,FAM174A,FATE1,RHOG,STX1A,PHB1,PTPN1,RAC2,STX5,HSD17B11,MFSD5,RHOH,CX3CL1,TLCD4,STX6,TMEM205,DNAJC25,STX12,STX8,CYBRD1,EMC2,PELI1,KRAS |
| 7.485e-06 | -11.80 | RNF20 (ring finger protein 20) | protein interactions | 56254 | 197 | 84 | 19454 | 5460 |
HNRNPK,XPNPEP1,HNRNPF,KRAS,CAPZA1,MSL2,UBE2A,RNF20,PCNA,UBE2B,RAB6B,DISC1,CDK8,RHOBTB1,MOB3C,RNF126,POLR2C,RBPJ,TP53,SUPT5H,RBM12,SNAP29,GTF2E2,TRAF2,PRNP,SUMO2,CAND1,G0S2,RPL35A,DCUN1D1,SLAIN2,CDK9,NCBP2,ALYREF,PLEKHO2,AGR2,PSMD7,H2AC4,MED21,TSNAX,USP15,RB1CC1,KXD1,PSMD3,PRPF19,TPM3,ELOC,DIS3L,INSYN1,STAU1,SGF29,UNC45A,ZDHHC17,PML,LMNA,MED23,HEXIM1,PGRMC1,NUP62,INSYN2A,FBXL19,VIRMA,UBE2L3,CMTR1,CPSF1,STUB1,RPS3,POLR3H,BRCA1,PSMD14,UBE2H,DNAJB6,CDC73,OAZ1,CUL3,OLFM3,PTPN11,DSN1,AKT1,MYC,AR,RNF40,FBXO7,BRAP |
| 7.522e-06 | -11.80 | STK24 (serine/threonine kinase 24) | protein interactions | 8428 | 163 | 72 | 19454 | 5460 |
CCT5,ATP5PB,ACTR1A,PPP2R1A,MRPL49,GEMIN7,PPP4C,CCR1,CCT8,SIKE1,CTTNBP2,SCPEP1,KPNA2,PSMA5,MCM6,HDAC6,XPO1,PSMD7,SMAD4,ANKRD49,DDX23,PDCD10,PSMB4,PPP2CB,TRAF3IP3,RPL12,SYNCRIP,FABP5,TCP1,SPPL3,CEP19,WIF1,CDC5L,CCT7,ZBTB2,SLMAP,ATG16L1,ISOC1,RPA2,VAV2,WRAP53,HNRNPH3,STK26,DDX5,HSPA8,HSCB,PRCP,G3BP2,SUB1,RAB11A,FGFR1OP2,STK38L,TNFAIP3,STK24,CCT2,SMPD2,OSGEP,STK11,S100A6,DOK4,TRMT6,MSN,MOB4,GANAB,CAB39,TUBB,MED17,DYNLL1,PSMD6,MATR3,MAT2B,CTTNBP2NL |
| 7.522e-06 | -11.80 | PHF5A (PHD finger protein 5A) | protein interactions | 84844 | 163 | 72 | 19454 | 5460 |
SRSF1,PCBP4,FZR1,SUMO2,COMMD6,VPS26C,SNRPD3,SNRPA1,MRPL50,DHX15,ZBTB2,RBM17,PFDN5,HNRNPA1,API5,SKIC8,DDX23,SNRNP70,SNIP1,HSPD1,EMC2,G3BP1,SNRNP48,KRAS,TOLLIP,S100A10,ROCK2,SNRPG,RAF1,NUP153,CD2BP2,EZH2,DDX42,SKA3,SMNDC1,PDHA1,SF3B5,NUPR1,SNRPE,SF3B6,SF3B4,SNRPD2,SNRPD1,ZMAT5,MATR3,RPL35,TAX1BP1,SRPK2,SNRPB2,ADPRM,MYC,SUGP1,PRPF31,DNAJC8,SNRPB,TTC33,ZCRB1,PFDN4,CDC73,UBE2H,RIT1,RBM7,DDX46,SF3B1,YAF2,UFL1,FBXW7,ZDHHC17,AATF,SF3A1,HEXIM1,CSNK1A1 |
| 7.522e-06 | -11.80 | EPAS1 (endothelial PAS domain protein 1) | protein interactions | 2034 | 163 | 72 | 19454 | 5460 |
MED4,KPNA1,AKAP8L,MED29,DDX23,SPP1,IKBKB,MED27,CSTA,ELOC,CTNNB1,XPO1,BCL7C,DPY30,EGLN3,ELK1,POLR2I,MITF,G0S2,PSMB1,MYBL2,MAP1LC3A,S100A8,PHB1,SMAD3,SIN3A,PSMC3,SSBP3,POLR2D,POLR2G,SMARCB1,POLR2C,HILPDA,JUN,YTHDF2,BATF,MAX,EIF3E,GTF3C3,CNOT7,BAG2,EWSR1,MEF2C,PRSS1,SP1,HSP90AA1,ICAM1,MED10,KPNA6,MCM3,PSMD1,OTUD7B,CUL2,MED22,CREBBP,VIRMA,EGLN2,MED17,STAT5A,NDN,STUB1,RPRD1B,USP39,MED23,JUP,PHB2,KDM1A,MED11,DDIT3,SQSTM1,EP300,XRCC5 |
| 7.540e-06 | -11.80 | human chr6p21.33 | chromosome location | human chr6p21.33 | 103 | 43 | 26134 | 5823 |
ATAT1,PSORS1C2,DXO,ATP6V1G2,PPP1R10,NRM,LY6G6C,LTA,IER3,ABCF1,NCR3,MRPS18B,LTB,CDSN,MCCD1,DDR1,MIR877,DDX39B,DDAH2,LSM2,AIF1,TCF19,GTF2H4,GNL1,MDC1,MICB,FLOT1,PRRC2A,LY6G5C,NFKBIL1,TUBB,SAPCD1,CSNK2B,MPIG6B,PPP1R18,DHX16,POU5F1,TNF,NEU1,CYP21A2,CCHCR1,LST1,PRR3 |
| 7.552e-06 | -11.79 | regulation of neuron apoptotic process | biological process | GO:0043523 | 244 | 104 | 18204 | 5365 |
NONO,CDK5R1,ATF4,TRAF7,FASLG,DDIT3,IL6ST,PRNP,MAP3K12,BACE1,HTR2A,CNTFR,ANGPT1,CCL3,SOD2,CDC42,NUPR1,UBB,ROCK1,STAMBP,SNCB,BAX,MIR200A,GBE1,DLX1,TP53,NTF4,PIK3CA,KCNB1,PSEN1,NTRK2,RETREG1,MYBL2,DNAJC5,GPRASP3,MCL1,NQO1,HTRA2,BTG2,MEF2C,CASP12,MIR195,UCN,AGAP2,PYCR1,PTPRZ1,MIR181C,EGR1,VSTM2L,SIGMAR1,MECP2,NR4A2,CLN8,RAD21,FBXO7,HRAS,FBXW7,MIR98,FCGR2B,AIFM1,DKK1,NDNF,CDK5,TGFB3,GCLC,CLU,MT3,PHB1,EGLN3,CTNNB1,SLC1A1,CX3CR1,TGFB2,CX3CL1,PPT1,BOK,IL10,KRAS,SRPK2,MAP3K11,TNF,SARM1,UCP2,SOD1,CCND1,UBE2M,SLC25A27,VPS54,G6PD,NAE1,CD2AP,NEFL,ADNP,CITED1,CASP4,EGLN2,TERT,PCSK9,NRP1,BCL2L1,NPPC,STXBP1,JAK2,CCL2 |
| 7.556e-06 | -11.79 | AKAP12 (A-kinase anchoring protein 12) | protein interactions | 9590 | 138 | 63 | 19454 | 5460 |
RAC2,RAB35,AIFM1,FBXO32,STX6,CAV1,ARF6,KIF3B,RHOH,DYNC1I2,PRNP,HDAC6,LAMP3,GAPDH,STK4,CTNNB1,LAMP2,SAV1,RHOG,SHC1,NSDHL,SFXN1,FLOT1,KRAS,TOLLIP,MAP2K3,KBTBD4,ARFGEF1,TP53,RND3,PTEN,NECTIN2,SRC,VIRMA,LDHA,RHOJ,PRKCE,SAMHD1,RAB2A,RAB11A,KIF3C,RHOB,BRCA1,PRKCB,HSPA8,RAB5A,RHOU,BAP1,STX7,ADRB2,STAU1,CDC42,ELK4,CFTR,CLDN4,ARL15,SCLT1,PRKCA,DYRK2,ARCN1,CAV2,CDK1,MAP2K1 |
| 7.556e-06 | -11.79 | GRK6 (G protein-coupled receptor kinase 6) | protein interactions | 2870 | 138 | 63 | 19454 | 5460 |
STOML2,XPO1,FKBP4,TUBG1,NCR3LG1,DNAJC7,AHSA1,AKAP8L,HAX1,AIP,MAGED2,HSP90AB1,CACYBP,ILVBL,SNCB,CHRM3,TOP3B,NHERF1,RAD23B,CD83,MAP1B,EIF1AD,SLC25A10,CLPB,RPAP3,TTC4,CSE1L,DNAAF10,RCVRN,KRAS,PTGES3,UTP25,FKBP8,CIAO1,FBXO7,MRPL16,DNAJC10,SDF2L1,PFDN6,SERPINH1,ATP1A1,HSP90AA1,STUB1,PTPMT1,EDNRA,MANSC1,KCNIP3,PPP5C,PGRMC1,CNP,CDC42,ADNP,ATP5PO,RPA2,PIH1D1,FDFT1,PRSS23,RHOU,RPA3,SNCG,NUBP2,ADRB2,SLC31A1 |
| 7.566e-06 | -11.79 | RAB9A (RAB9A, member RAS oncogene family) | protein interactions | 9367 | 591 | 214 | 19454 | 5460 |
SCYL2,RETREG1,SEMA4C,RCVRN,FAF2,MACO1,CYB5B,STX12,GDI2,VAMP2,VPS33A,STIM1,RPN1,ATP6V1A,TSG101,WDR6,SLMAP,SNX1,SNX2,OCRL,WDR11,CLPX,CDK5RAP3,RHOG,PMAIP1,RABAC1,STX7,ATAD1,NOP53,RAB6A,DUSP22,RND2,PGRMC1,NOTCH2,TOR1AIP2,TMEM231,NDE1,RRAGA,ARCN1,VPS18,VAPB,SEC61B,ARF1,FAM91A1,BORCS7,LAMTOR3,MB21D2,RHEB,RAB11A,NOP16,VEZT,NIBAN2,SCFD1,RHOB,LMNB1,MYO6,SNAP23,DLG1,STX8,RAB1A,NSDHL,VPS16,ARF4,CTNND1,LBR,SLC29A1,CCDC47,VAC14,CDCA3,EHBP1,PTPN1,SRP14,SRPRA,HACD3,CAV1,ALCAM,LAMP3,HM13,LAMTOR2,KXD1,TMEM199,OSBPL8,ESYT1,SLC2A1,POR,MTDH,RTN4,MAVS,FLCN,SOD1,RPA3,RHOU,TMEM209,CERS2,YKT6,CNP,ARHGAP1,SEC22B,RABL3,BORCS8,GOLGA5,SLC12A2,AP1AR,SLC11A2,SCAMP2,VAMP3,OPTN,VIRMA,SEC63,FERMT2,SLC25A4,SNX3,RHOJ,YES1,HMOX2,RHOBTB3,DEPDC1B,EPHA2,XPOT,NAPA,ARFGAP3,RABGGTB,EFNB1,TMEM87A,POLDIP3,VAMP8,NUP42,SLC20A2,SPG21,TRAF2,SNAPIN,ARFGEF1,TRMT1L,STBD1,HGS,TAPT1,STX5,LANCL1,VAMP7,LYAR,RHOH,RAB1B,TBC1D5,DDRGK1,PPFIBP1,SLC38A9,RPL6,TSPAN10,LAMP2,SPHK2,AKAP1,TMEM106B,STAU1,GOSR1,UFL1,TOM1L2,BORCS6,BET1,TANK,MTMR6,TMEM184B,FAM8A1,FAM83B,ATP6AP2,MANSC1,ATP5F1B,SERPINH1,SLC38A1,FTSJ3,LAMTOR1,STX18,ATP2B4,RUSF1,FKBP8,SLC6A8,RBCK1,UBIAD1,SNAP29,PREB,EXOC3,TFRC,RAC2,SLC39A10,CAMLG,STT3A,LMAN1,SLC38A2,TMPO,STX6,VTI1B,MIOS,KARS1,ATP6V1D,DLAT,RAB9A,ARFIP1,BANF1,TEX264,GRPEL1,PIP4P1,CDC42,LEMD3,FGFR1,BORCS5,EIF2S2,NECTIN2,ATL1,SRC,GORASP2,C9orf72,CALU,ATP1A1,CHCHD4,SNX14 |
| 7.636e-06 | -11.78 | FKBP4 (FKBP prolyl isomerase 4) | protein interactions | 2288 | 261 | 106 | 19454 | 5460 |
MGME1,CD274,RB1,PHYH,PRNP,ARF6,LMAN1,FAM20C,CDC37L1,IRF4,TPM3,CSNK2A1,TRPC1,TAF9,DYNC1I1,PTGES3,TP53,MTCH2,ACTR1A,MAP1LC3B,ACVR1,ACTR2,CBX3,TSSK1B,CCNF,TXNDC12,PRKCE,NDN,KCTD9,VIRMA,SH3BP4,CAP2,AR,CHORDC1,UBE2H,STK11,CDC73,SIRT7,BAP1,RPA3,SQSTM1,FBXW7,SLC25A51,KDM1A,GABARAP,MAP3K12,SAMM50,RPA2,UBE2M,SH3GLB2,KRT8,DYNC1I2,PGR,NUP35,HSP90AB1,CACYBP,DIRAS3,IFI16,CTNNB1,XPO1,AGR2,IKBKB,HSPB1,AHSA1,CDK5,EWSR1,SAR1B,AP1M1,RAF1,SOX2,PRKAG1,CHMP4C,PLS3,GLE1,EZH2,MOB3C,POLR2C,STX12,S100A6,ANAPC2,TUBB,STAT1,PMPCA,MYC,MCM3,MCM4,ATG101,YWHAZ,FBXW11,BRCA1,DCAF4,LAMTOR1,PSKH1,ILK,SP1,HSP90AA1,LCA5,NPB,AKAP1,HSPA8,GPC1,PRKAB1,DET1,NEK7,PRDX3,FKBP1A |
| 7.653e-06 | -11.78 | Ub-specific processing proteases | REACTOME pathways | R-HSA-5689880 | 223 | 101 | 10285 | 3229 |
ADRM1,H2AC13,PSMA6,BECN1,MUL1,PSMD1,PSMB2,USP13,USP30,SNX3,PSMC1,SMAD4,H2AC6,PSMA1,TRAF2,USP3,TP53,PSMC3,AR,PSMD4,RNF146,RPS27A,PSMB4,USP5,UFD1,H2AC4,SEM1,RIGI,PSMA5,PTEN,USP14,MAT2B,TOMM70,PSMB3,H2AC25,H2BC14,RCE1,TAB1,H2AC1,MDM2,SMAD3,TAF10,UBA52,PSMD10,NFKBIA,IDE,VDAC1,SMAD1,PTRH2,TADA3,H2AC7,CFTR,USP16,PSMD12,RUVBL1,USP2,MYC,H2BC1,H2AC14,TOMM20,CCNA2,H2BC9,WDR20,RNF128,TRAF6,PSMD6,PSME2,BIRC2,TNKS2,HGS,PSMB9,PSMB10,PSMC5,PSMB11,SMAD2,H2BC17,PSMA4,POLB,H2BC11,TNKS,VDAC2,PSMA2,PSMB6,PSMB1,ADRB2,CDC20,PSMB7,PSMD3,PSMC4,PSMA3,PSMB5,SIAH2,PSMD14,UBB,PSME1,FKBP8,IFIH1,USP15,USP8,PSMD7,H2BC12 |
| 7.664e-06 | -11.78 | PTBP3 (polypyrimidine tract binding protein 3) | protein interactions | 9991 | 180 | 78 | 19454 | 5460 |
MIR205,RPA3,MIR10B,MIR34C,STAU1,MIR29A,MIR106A,MIR107,COIL,MIR34B,PABPC5,ATG16L1,MIR1-2,PICALM,RPA2,MIR7-1,NCOA5,MIR21,CMTR1,EIF4A3,MIR16-1,PHAX,PRKRA,MATR3,COPE,ESR2,SLC25A31,HNRNPC,IFI35,MIR98,TAS2R39,DCAF4,FTSJ3,MIR145,FYTTD1,CALU,ELAVL2,MIR363,MIR200A,BAG2,TRIM11,MIR206,ZC3H11A,MIR155,G3BP1,MIR16-2,PPWD1,MIRLET7C,E2F4,RAF1,SOX2,MIR222,APOO,CD2BP2,MIR200C,MIR17,MIR20A,CCR1,ILF2,MIR7-2,EEF1AKMT3,MIR106B,MIR25,MIR141,PRR3,CDC5L,MIR429,NCBP2,MIR143,MOV10,UBXN6,MIR29C,MPHOSPH10,MIR31,MIR34A,MIR140,MIR221,MIR1-1 |
| 7.725e-06 | -11.77 | LARP4 (La ribonucleoprotein 4) | protein interactions | 113251 | 200 | 85 | 19454 | 5460 |
NUP35,CDK9,RBM42,LSM5,CGAS,RPS10,HNRNPL,FZR1,RPS16,PAIP1,PRR3,SRSF1,SYNCRIP,PTPN1,DRG1,RPS2,SNRNP70,DDRGK1,MPG,CPEB1,MARCHF5,WWP2,PFDN5,CALR,IFI16,MOV10,EIF2D,FKBP8,PAX6,PFDN1,G3BP1,ZC3H7A,PABPC1,BHLHE40,RNF126,HBP1,RPS7,APOBEC3D,YTHDF2,RPSA,MTCH2,NAA35,B3GNT2,TOP3B,RAF1,APEX1,SRC,RPL10,MGST3,RPS12,RPS20,RMDN3,PSMA6,SMAP2,RPS3,PSPC1,CCNF,MAPRE1,PAIP2,PFDN2,IGF2BP1,RC3H2,CUL3,APOBEC3B,MYC,G3BP2,TOMM20,YTHDF1,STAU1,AKAP1,EP300,EXD2,PML,SIRT7,RPS28,HECTD1,DYRK2,LARP4B,GRM2,CCL3,RBMS2,RPS14,TXNL4A,PABPC5,TOMM22 |
| 7.730e-06 | -11.77 | HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2) | protein interactions | 8924 | 442 | 166 | 19454 | 5460 |
MAPKAPK5,FHOD3,TANK,MRPL12,SOST,FDFT1,DDX39B,EXD2,HERC3,SPECC1L,RAB5A,UBE2D3,CCDC186,RER1,DUSP26,RADX,ZDHHC17,ZBTB5,RNF11,PSMC1,SELENOO,FTL,MYC,CFAP20,BTF3,PSMD1,RMI2,MLF2,MED10,BRCA1,LMNB1,PSMD14,THOC6,RMI1,VDAC2,EIF3K,RPS9,PHKB,CLXN,USP16,MED17,AIPL1,RPL35,ESR2,TOP3B,RAF1,B3GNT2,HSDL2,SNAPIN,NUP153,ASPM,ERLIN2,TUBB4B,PNMA2,MRFAP1L1,PABPC1,ARGLU1,ABCF1,UBE3A,RPS24,PELI1,ETFA,SRSF4,LAMP2,INPP4A,DPY30,NDC80,ZCCHC10,PTDSS1,XPO1,CTNNB1,EIF3D,CSTA,MRPL18,UBE2D1,PPM1B,PSMD10,DDX1,RB1CC1,MED4,PSMB4,MPDU1,OCRL,FAM98A,DHX15,NUF2,PSMC4,SNRNP27,MED30,MRPL10,CDC42,FTH1,LMNA,RPA2,ZCCHC17,CDR2,TFIP11,LUC7L3,RPA3,DDX46,MAPKAPK3,SIRT7,LCP1,MAVS,CCDC65,EIF5B,FBXW7,RPL7A,PHKA1,EIF3G,BICD2,CCDC22,STK11,AP3S2,UBE2H,PPIG,MAPRE1,CCNF,MRPL53,PELP1,CTNNA1,EIF4A3,EPCAM,ZNF622,BUB3,COPE,MAGOHB,UBE2L3,VIRMA,RPL22,TBK1,TP53,DDX39A,SURF4,CDK8,DISC1,RNF8,TAF2,EHD4,ZNF451,SLC16A1,RNF115,TMEM33,DNAAF10,FASTKD5,MDC1,EIF3E,ENY2,HM13,TMA16,SUV39H1,SSX2IP,CDK12,DNAJC7,MAP4,PDE9A,SSBP1,PTPN1,UBE2N,RPL35A,MIOS,TOP1,NKAP,DKC1,MDM2,AKAP17A |
| 7.736e-06 | -11.77 | regulation of cardiac muscle hypertrophy | biological process | GO:0010611 | 69 | 38 | 18204 | 5365 |
CAV3,MIR145,MEF2A,MIR1-1,GSK3A,ROCK1,PARP2,ROCK2,SMAD3,MTPN,FOXP1,MIR34B,ATP2B4,IGF1,SMAD4,MIR21,PPARA,HAND2,PPARG,TRIM63,TOMM70,IL6ST,BECN1,RGS2,MIR25,PI16,ADRA1A,MIR34C,G6PD,PPP3CA,MIR214,MIR17,MIR20A,PDE9A,TNFRSF1B,MIR208A,PRKCA,LMNA |
| 7.769e-06 | -11.77 | RNF111 (ring finger protein 111) | protein interactions | 54778 | 95 | 47 | 19454 | 5460 |
CFAP298,UBE2I,AP2M1,CSNK2B,FBLN5,CREB1,VIRMA,UBE2V2,CREBBP,SUGP1,SETD7,SMAD2,HSP90AA1,PHF7,RBM27,UBE2E3,PML,UBE2K,UBE2D3,UBE2W,SUMO1,UBE2M,VAPB,CTBP1,NRSN1,TSG101,UBE2G2,UBE2N,SMAD3,CGGBP1,SUMO2,SUMO3,TTC9C,CSNK2A1,TRIM8,UBE2E2,MDFI,CDK12,RB1CC1,UBE2D1,TRIM21,PAX6,ANAPC11,UBE2V1,GNAQ,DCUN1D5,NFE2L2 |
| 7.802e-06 | -11.76 | RANGAP1 (Ran GTPase activating protein 1) | protein interactions | 5905 | 267 | 108 | 19454 | 5460 |
KDM2A,PPP2R5A,BABAM1,DDRGK1,PPIB,XPO1,SUMO2,SUMO3,NUP35,EGLN3,SRSF1,PDHA1,TUBB4B,RBPJ,E2F4,RANBP1,SUPT5H,FOXJ3,SOX2,DNAJC25,JUN,NUP153,GNL1,UFM1,KRAS,H1-6,GTF3C3,BRCA1,LMNB1,OSGEP,CUL3,RAB11A,MYC,ESR2,ATP6AP2,DLST,RAN,CPSF1,LMBR1L,SEC61B,CSNK1A1,ARHGEF39,STAU1,EEF1G,EMC1,PCGF2,EP300,HSPA8,H2AC4,NXT2,MUL1,CALR,CCL5,NEUROD6,CSNK2A1,CDC5L,RCHY1,CTDSPL2,ACTR2,DISC1,NUPR1,GNAI3,SH3GLB1,TOPORS,TP53,IPO8,KBTBD4,PPIF,H2AX,HUWE1,NUP107,RIGI,MEPCE,PSEN1,EMC2,THG1L,UBE2E3,BICD2,NIF3L1,UBE2H,SORD,CALU,MAPRE1,SUB1,RUNX1,DEPDC1B,VIRMA,CCNF,UBE2I,PTEN,ZCCHC17,CDK1,RPA2,LMNA,RPRD1B,TFIP11,UBE2M,SUMO1,CPSF4,B2M,TMUB1,PML,SIRT7,ARHGEF6,RPA3,BAP1,PRDX6,ARPC2 |
| 7.864e-06 | -11.75 | CHM (CHM Rab escort protein) | protein interactions | 1121 | 57 | 32 | 19454 | 5460 |
RAB5C,RAB11A,RAB3D,RAB2A,RAB32,UBE2H,RAB3A,RAB9B,RAB31,RAB35,RAB11B,RAB33A,ADRM1,CCAR2,RAB14,RAB1B,RAB6A,KIF2A,TP53,RAB4A,RAB6B,RAB5A,RAB9A,RAB33B,RAB27A,RAB30,RBM3,RAB29,RAB1A,RAB8B,RAB18,RAB3B |
| 7.873e-06 | -11.75 | lysosome | cellular component | GO:0005764 | 762 | 276 | 19108 | 5553 |
TLR8,OSTM1,ATRAID,WDR11,CTSK,GPR137,TRIM29,VTI1B,CHMP1A,TRAPPC1,HSP90AA1,BORCS8,RNASET2,MYO6,CYB5R3,SESN2,CHMP4C,ARRDC3,FTH1,PRELP,BLOC1S2,CHID1,CD63,PYCARD,ACTR2,PRCP,PLA2G15,KLC2,SDC4,PIP4P2,CYB561,SLC48A1,CMTM6,TNFAIP8L2,TMEM59,CHMP5,NDUFC2,AP5S1,SAR1B,EVA1A,FMOD,MREG,NEU1,LUM,FLCN,CD1C,SLC17A5,B2M,SERPINA3,CRHBP,PPT1,LDLR,SLC38A9,AP1S2,TMEM203,DNAJC3,GLIPR1,ATP6V1A,CHMP1B,CD164,MIOS,NCSTN,B4GALT1,RNASE6,HYAL2,CCT8,HGS,RHEB,ENTPD4,IFNAR1,VPS33A,RAB2A,OGN,RNF152,DPP4,CTSA,TM9SF1,BORCS5,TMEM106B,TAB2,CYBRD1,TRIM23,RETN,TMBIM1,SQSTM1,CCT2,ATP6V0B,KICS2,NSG1,UBXN6,TMEM199,ATP6V1C1,STOM,SDC2,ZNRF1,ATP6V0E1,GNAQ,FTL,PYGB,NAPG,SNAP29,VAMP8,GPC1,TOLLIP,VPS26A,LAMP2,PLEKHF1,BORCS7,CAPN2,IL1B,LAMTOR3,FAF2,LITAF,CD34,RNF167,PSEN1,BST2,HEXB,GNB4,SERPINB1,RAB14,RRAGA,PRDX6,MARCHF3,LAMP5,CTSD,LIPA,ABHD6,TUBB4B,STX7,SNX14,SLC11A2,PCSK9,AP2M1,SPHK2,CPNE1,ATG16L1,TLR9,HEXA,HSPA8,MMD,GPC4,LAMP3,ACP2,RAP1B,ATP8A1,VPS39,RAB3A,GNB1,VPS4A,ACP5,DRAM1,BACE1,TTR,LAPTM4A,RAB5C,SLC2A8,SNAP23,ATP6AP2,SNAPIN,CHMP2A,MCOLN1,LAMTOR2,TLR7,TMEM74,CDIP1,RAB9A,FCMR,GNA11,LRRC8A,PLAAT3,TFEB,TMEM165,TMEM45B,VAMP7,SEC13,TLR3,TRAF3IP3,FLOT1,GALC,ENPEP,BRI3,CLCN6,RAB27A,FABP5,HPS6,VPS16,ATP6V1G1,PADI2,SYNGR1,HEBP2,LMBRD1,CTSC,GCA,LAMTOR1,TOM1,VPS18,GDI2,CRYAB,SRC,SLC38A7,RAB37,PLD3,STX17,CHMP2B,TMEM30A,DNAJC5,TOM1L1,SFTPD,ADRB2,RAMP3,RRAGB,TFE3,TASL,ABCB9,UBA52,PSMD1,AP2S1,SURF4,FASLG,USP5,SNX1,RAB3D,ATP6V1D,RAB9B,STARD3NL,RNASEK,C9orf72,VLDLR,AP1M1,AP2A1,GNAI3,CXCR4,MAP1LC3A,SDCBP,CD1E,SRGN,SNX2,CFTR,CD1B,CTSB,GGH,USE1,CALR,OCRL,VAMP1,CD1D,LYZ,PIP4P1,SLC7A14,BCL10,SLC35F6,AGA,OCIAD2,SIAE,CAPN1,TMEM97,BORCS6,GNPTG,KLHL22,AP5M1,MINAR2,TMEM179B,RB1CC1,PLAC8,KXD1,DSN1,TUBB,GABARAP,MLC1,TNFAIP3,EEF1A1,NPC2,MITF,PLA2G5,MARCHF9 |
| 7.873e-06 | -11.75 | lytic vacuole | cellular component | GO:0000323 | 762 | 276 | 19108 | 5553 |
SAR1B,MREG,FMOD,EVA1A,AP5S1,NDUFC2,CHMP5,SLC17A5,LUM,NEU1,CD1C,FLCN,LDLR,PPT1,AP1S2,SLC38A9,B2M,CRHBP,SERPINA3,DNAJC3,TMEM203,ATP6V1A,CHMP1B,GLIPR1,FTH1,CHID1,PRELP,BLOC1S2,ACTR2,CD63,PYCARD,PIP4P2,SDC4,PLA2G15,PRCP,KLC2,CMTM6,TMEM59,TNFAIP8L2,SLC48A1,CYB561,TRIM29,CHMP1A,VTI1B,TRAPPC1,HSP90AA1,BORCS8,MYO6,CYB5R3,RNASET2,ARRDC3,CHMP4C,SESN2,TLR8,ATRAID,OSTM1,GPR137,WDR11,CTSK,LAMTOR3,CAPN2,IL1B,SERPINB1,HEXB,BST2,GNB4,RAB14,RRAGA,CD34,LITAF,FAF2,RNF167,PSEN1,MARCHF3,PRDX6,TUBB4B,ABHD6,STX7,SLC11A2,SNX14,LIPA,LAMP5,CTSD,UBXN6,TMEM199,ATP6V1C1,STOM,NSG1,ATP6V0E1,NAPG,PYGB,FTL,GNAQ,SDC2,ZNRF1,VAMP8,GPC1,SNAP29,PLEKHF1,BORCS7,LAMP2,VPS26A,TOLLIP,TM9SF1,BORCS5,TMEM106B,TAB2,CYBRD1,RETN,TRIM23,ATP6V0B,CCT2,KICS2,TMBIM1,SQSTM1,MIOS,CD164,ENTPD4,RHEB,HGS,HYAL2,CCT8,NCSTN,RNASE6,B4GALT1,OGN,RNF152,VPS33A,IFNAR1,RAB2A,CTSA,DPP4,HEBP2,SYNGR1,ATP6V1G1,PADI2,VPS16,HPS6,LAMTOR1,TOM1,LMBRD1,GCA,CTSC,SRC,CRYAB,VPS18,GDI2,PLD3,TMEM30A,CHMP2B,STX17,RAB37,SLC38A7,LRRC8A,GNA11,VAMP7,SEC13,TMEM45B,TFEB,PLAAT3,TMEM165,TRAF3IP3,GALC,FLOT1,TLR3,CLCN6,BRI3,FABP5,RAB27A,ENPEP,SNAP23,SLC2A8,RAB5C,ATP6AP2,CHMP2A,SNAPIN,MCOLN1,CDIP1,RAB9A,FCMR,TMEM74,TLR7,LAMTOR2,TLR9,HEXA,AP2M1,PCSK9,SPHK2,CPNE1,ATG16L1,RAP1B,ATP8A1,HSPA8,ACP2,LAMP3,GPC4,MMD,RAB3A,VPS39,GNB1,TTR,LAPTM4A,BACE1,VPS4A,ACP5,DRAM1,BORCS6,TMEM97,SIAE,OCIAD2,CAPN1,GNPTG,AGA,SLC35F6,RB1CC1,KXD1,PLAC8,KLHL22,AP5M1,TMEM179B,MINAR2,MLC1,GABARAP,TUBB,DSN1,MITF,MARCHF9,PLA2G5,EEF1A1,NPC2,TNFAIP3,CD1B,CFTR,CD1E,SRGN,SNX2,USE1,CALR,OCRL,GGH,CTSB,LYZ,CD1D,PIP4P1,VAMP1,BCL10,SLC7A14,SURF4,FASLG,RAB3D,ATP6V1D,USP5,SNX1,VLDLR,C9orf72,RNASEK,AP1M1,AP2A1,RAB9B,STARD3NL,CXCR4,MAP1LC3A,SDCBP,GNAI3,SFTPD,DNAJC5,TOM1L1,RAMP3,ADRB2,ABCB9,TASL,TFE3,RRAGB,PSMD1,AP2S1,UBA52 |
| 7.895e-06 | -11.75 | GMPS (guanine monophosphate synthase) | protein interactions | 8833 | 152 | 68 | 19454 | 5460 |
EGLN3,CDC5L,HNRNPL,MTAP,FBXO32,MYEF2,HSPB1,GSTO1,ATG7,DDRGK1,GLO1,BABAM1,RIGI,SAR1B,PAX6,KRAS,RPIA,HAPSTR1,TRIM21,RAB1A,GLUL,PPME1,MOB3C,GPX7,TFRC,EZH2,CHMP4C,CCS,GGCT,GTF2E2,TP53,SUCLG2,TCEAL1,PNP,CTSB,PSPC1,PAPSS2,CCNF,ENO2,EFHD2,RIT1,UBE2H,BRCA1,MTPN,RUNX1,AR,USP14,MYC,SLC25A1,GFUS,CUL3,PMPCA,UFL1,CRY1,HSPA8,DDX5,EP300,BAP1,PPM1G,RPA3,SIRT7,UBE2M,PIH1D1,ACACA,PAK2,ADSS2,RPA2,PCK2 |
| 7.895e-06 | -11.75 | STMN1 (stathmin 1) | protein interactions | 3925 | 152 | 68 | 19454 | 5460 |
RPA3,PPM1G,DDX39B,SOD1,BAP1,PEBP1,RPS28,ATP5IF1,HSPA8,PGK1,EP300,RLIM,GPC1,STAU1,GRPEL1,HSPA5,CDC42,PRDX3,DUSP22,RPA2,LMNA,CDK1,RPRD1B,PRKCA,MYL6,SESTD1,TUBA1B,TRIM24,PDCD5,CYP4F12,CUL3,CDKN3,JPT1,BAG3,PFDN2,UHMK1,UBE2H,RAB1A,CAMK2G,HUWE1,HSPE1,PIWIL1,ANP32B,AHCYL1,IMPA2,ANP32A,EZH2,TUBB4B,STMN2,GDI2,JPT2,CD274,TYMS,MIF,SUMO2,SIVA1,CALR,PDIA3,PGAM1,PPIB,COPS5,CSNK2A1,TPM3,FOSL2,CNTFR,AGR2,CDKN1B,HSPB1 |
| 7.907e-06 | -11.75 | CPD (carboxypeptidase D) | protein interactions | 1362 | 166 | 73 | 19454 | 5460 |
LAMTOR1,RHOB,EPHA2,NTRK3,NRP1,RIT1,RAB2A,MTG2,RAB11A,DNAJC5,TENT5C,VIRMA,APEX1,LMBR1L,SEC61B,FGFR1,MET,CLDN4,BET1,OTULINL,RND2,CDC42,SEC62,ST7,HSCB,STX7,AATF,RHOU,TMEM106B,RAB5A,DERL1,RAB9A,SMAD4,RHOG,STYK1,DPP4,LAMP2,ATG9A,RAB5C,LAMP3,DNAJC1,HNRNPL,ARF6,RHOH,DIRAS3,LMAN1,STX6,CAV1,RAB35,GJA1,HSD17B11,RAC2,STIM1,TFRC,RPN1,RAB4A,PTRH2,RND3,FURIN,UBL4A,IL1R2,DNAJC25,LGR4,KRAS,TNF,EPHA4,RAB3B,CD1B,AP1M1,IMMP2L,TMT1A,IGF1R,COX8A |
| 7.913e-06 | -11.75 | GRWD1 (glutamate rich WD repeat containing 1) | protein interactions | 83743 | 381 | 146 | 19454 | 5460 |
SLC25A3,PPP1CB,RPL27A,COIL,UFL1,HNRNPA0,STAU1,SF3B1,EP300,HADHA,RFC4,HSP90AA1,RCL1,PFDN6,CCT2,ATP1A3,FAS,H1-10,RFC5,SNRPB,MYC,CUL3,HNRNPC,GRB10,POLR2B,RPL10,ESR2,MATR3,RPL37A,DTWD2,RPS11,RHOBTB1,RPS23,RPL18,RPN1,CHMP4C,H1-3,EEF2,TOP3B,E2F4,RPL28,GTF3C3,RFC3,RFC2,KRAS,G3BP1,RUVBL1,MYO1B,RUVBL2,PCNA,EWSR1,TRIM11,RPL31,CCT8,TOP2B,DDX1,RPL23,RHOG,XPO1,DDRGK1,IFI16,DDX50,PFDN5,WWP2,RPL6,HSP90AB1,DHX15,CCT7,RPL7,TCP1,SPTAN1,RHOH,MAGED2,HP1BP3,RPL8,RPL9,PHB1,HEXIM1,CDC42,POLR1D,ATG16L1,MARS1,RPL4,SMC4,MTDH,RNF113A,PPM1G,RHOU,ATP1A1,UBE2H,RC3H2,RPS17,RPL26,USP14,PPP1CC,SLC25A1,CCNB1,RPL7A,SEC13,BCCIP,RPL22,RPL13A,RHOJ,MRPS28,CDIPT,MLLT11,ILF2,NUPR1,DNAJC2,TP53,CCT5,YTHDF2,MEPCE,RPS13,RPL17,H3C1,HUWE1,THRAP3,RPL3,RPL23A,DHX9,SLC25A10,FAF1,METTL18,NKRF,SLC25A11,SFXN1,RPS2,RPL10A,SNRNP70,RPL24,COPS5,GAPDH,MOV10,SLC25A12,ZBTB2,CDC5L,CAND1,FZR1,CGAS,TOP1,RAC2,RPL12,AIFM1,MRPS9,RPL32 |
| 7.929e-06 | -11.74 | SUB1 (SUB1 regulator of transcription) | protein interactions | 10923 | 229 | 95 | 19454 | 5460 |
CHORDC1,STK24,PIM2,SMAD2,UBE2H,SUB1,ST13,SMURF1,CCNF,OPTN,ZNF330,EIF2S2,CSNK2B,SDCBP,RPA2,METTL14,WTAP,UBA52,GTF3C4,CDK7,CFTR,FBXW7,NHP2,HSPA5,BAP1,RPA3,BANF1,KPNA1,CSNK2A1,TOP1,TMPO,DKC1,CDC5L,SMAD3,SH3GLB1,FBP1,TP53,ACTR1A,HUWE1,RIGI,EIF1AD,GLUL,RAB27A,SEPTIN7,EMC2,DHX9,ATG3,SP1,MYC,SFN,CUL3,IRF1,MATR3,CBX5,POLR2B,ESR2,PIH1D1,NEK7,SRSF2,EMC1,UFL1,UNC45A,HSPA8,EP300,COMMD2,DDX23,DRG1,LAMP2,YWHAG,XPO1,YWHAH,DDRGK1,CTNNB1,HNRNPL,COMMD6,PTK7,FOLR1,CLK4,SRSF1,PRCC,EZH2,EIF1AX,MTA2,AAMP,NAA15,TOP3B,SUPT5H,TRIM37,GTF3C3,SSRP1,SCYL2,ABCF1,ARGLU1,CDK5,PCNA |
| 7.929e-06 | -11.74 | PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase) | protein interactions | 5110 | 229 | 95 | 19454 | 5460 |
KLHL26,TFCP2,TP53,KBTBD4,RPIA,HUWE1,HSD17B10,KLHL24,CLP1,COPS5,HDAC6,DPP4,MIF,CAND1,KCTD3,AKR1B1,MTAP,PTPN1,UBE2M,HEXIM1,DYRK2,CYB5R4,LMNA,RPA2,CFTR,SPR,PIAS1,YKT6,PPIH,CSTB,BAP1,RPA3,SOD1,UBE2H,BICD2,DYRK1A,VIRMA,SH3BGRL,SNX3,CCR2,DTYMK,ZBTB18,ENO1,CCNF,MOB3C,FAM136A,ZRANB2,EZH2,SOX2,CSNK1E,B3GNT2,PAX6,TRIM37,ETFA,SCYL2,POU5F1,AGR2,DDRGK1,CRIP1,COPS7B,SDHAF2,FOLR1,PIH1D1,PPT1,PSMB7,TAAR1,NOTCH2,RNF41,STAU1,UCHL3,EIF1B,UFL1,RAB5A,HDAC5,COX17,HSPA8,TMEM106B,PFDN2,BRCA1,RBBP8,CUL2,LDHB,CUL3,HNF1B,MYC,CREBBP,KBTBD6,ESR2,SSH3,AKR1C2,MATR3,PRDX2,DLG4,ENO2,DLST |
| 7.948e-06 | -11.74 | FLOT2 (flotillin 2) | protein interactions | 2319 | 273 | 110 | 19454 | 5460 |
SMAD2,EPHA2,DNAJC19,USP14,DNAJC5,AR,GORASP2,AKT3,RAB2A,SRC,STAT5A,RHOJ,YES1,CSNK1G3,WWP1,SSR1,FGFR1,CDC42,CFTR,UQCC3,MAVS,RAB9A,MME,RPA3,RHOU,IRF3,HDAC6,LAMP3,COPS5,DPP4,IRF4,EPHB6,STX6,CAV1,ARF6,CGAS,PRNP,RAC2,CDCA3,PTPN1,ETV6,NUPR1,TFCP2,TFRC,DXO,DISC1,TUSC3,CHMP1B,RAB3B,RING1,ABCE1,NTRK2,DDR1,FIS1,LAMTOR1,RHOB,MYO6,BTF3,TOMM40,MYC,CUL3,RAB11A,ESR2,ATP6AP2,APEX1,VDAC2,GNG12,CCDC90B,DLST,ELF5,CAV2,RND2,BET1,STX7,TMEM185A,RAB5A,BMPR1A,CBL,HAX1,PEX3,DEGS1,RHOG,ZCCHC9,YWHAH,LAMP2,SYNJ2BP,MARCHF5,RAB5C,DIRAS3,RHOH,GJA1,EED,RAB35,MYEF2,RND3,HGS,IRF8,EZH2,VAMP2,RAB4A,PTRH2,ISG15,EEF2,ERLIN2,UBE2A,TFG,FLOT1,KRAS,EPHA4,VDAC1 |
| 7.953e-06 | -11.74 | positive regulation of tumor necrosis factor production | biological process | GO:0032760 | 109 | 54 | 18204 | 5365 |
MIR657,PSEN1,LILRA2,CCR2,CCL19,MYD88,MIR206,CD14,TLR2,PIK3R1,IFIH1,TLR9,SETD4,OAS1,IL23A,CD36,MAVS,SPHK2,TIRAP,TLR1,TICAM1,RIGI,JAK2,TYROBP,PYCARD,IFNGR1,AGER,LEP,TLR4,PTPN11,FCGR2B,DHX9,DDT,SASH3,HMGB1,SYK,CLU,CCL3,MIF,TMEM106A,LY96,SELENOK,HSPB1,FCGR2A,CLEC7A,FRMD8,IL6,AKAP12,IL1A,TLR3,MIR144,IFNG,IL12B,CD2 |
| 7.973e-06 | -11.74 | EEF1B2 (eukaryotic translation elongation factor 1 beta 2) | protein interactions | 1933 | 183 | 79 | 19454 | 5460 |
CDK9,UQCRH,FZR1,CAND1,CD4,EED,PHB1,EEF1B2,CD274,HSPB1,RPS2,MGMT,CBL,AGR2,DDRGK1,CSNK2A1,HDAC6,MOV10,MEPCE,HUWE1,HSD17B10,EWSR1,ATF3,FAF1,HSPD1,RNF8,MTA2,CHMP4C,TFCP2,EZH2,MLLT6,NUP153,H2AX,EEF1A1,SOX2,ESR2,VIRMA,SMURF1,SH3BGRL,TENT5C,NDN,GTF2F1,ENO1,CCNF,OPTN,UBE2H,BRCA1,TIMP1,CUL2,RPL7A,CUL3,MYC,HSPA5,ADRB2,FBXW7,EEF1G,GPC1,UFL1,PSMA3,EP300,HSPA8,WBP2,SNRPA,BAP1,RPA3,SOD1,DDX39B,PIH1D1,UBE2M,HEXIM1,ARMCX3,WWP1,DRD3,SPRYD4,RPA2,CDKN1A,CDK7,CFTR,TPT1 |
| 7.973e-06 | -11.74 | QKI (QKI, KH domain containing RNA binding) | protein interactions | 9444 | 183 | 79 | 19454 | 5460 |
SOX2,THAP1,RAF1,CENPM,VAC14,CYB5B,IL7,EWSR1,BAG2,FHL3,TRIM11,MIR200A,FKBP2,USP30,HNRNPK,HNRNPA1,UTP6,DDRGK1,LSM3,MED4,MED27,MED29,SNRNP70,TSG101,PCBP4,PRR3,MIR141,HCLS1,SYNCRIP,RPL9,NABP1,FUBP3,RBM42,FZR1,HNRNPL,LSM5,PRNP,HYPK,SNRNP27,RBMS2,DUSP22,MIR34B,WDR77,DUSP14,RBFOX2,TXNL4A,PAX9,MIR7-1,MED31,MED23,HSPA8,HNRNPH2,MIR34C,SNRPA,RBM23,ZKSCAN1,PIAS1,CCND3,AATF,UFL1,OIP5,YTHDF1,FBXO7,MYC,CDKN2D,HNRNPC,IGF2BP1,ELAVL2,RBM7,MED10,DCAF4,CYP1A1,FBXW11,ZMAT5,LMBR1L,ESR2,APEX1,MED17,SNRNP40 |
| 7.973e-06 | -11.74 | RPS27L (ribosomal protein S27 like) | protein interactions | 51065 | 183 | 79 | 19454 | 5460 |
TUBA1A,CTDSP2,RPS7,RPL15,RPSA,RPS11,SRP72,RPL18,RPS23,CHMP4C,RPL23A,RPS24,RPL31,RPS13,RPS4X,MEPCE,RPL17,TNF,G3BP1,FGD2,EIF4EBP2,MAP3K14,RPL6,WWP2,RB1CC1,RPS2,DRG1,RPL10A,RPL23,RPL24,SNRNP70,AGR2,RPLP2,SYNCRIP,RPL9,RPL12,PHB1,RBM42,MDM2,RPS16,EIF2S1,RPL35A,SNRPD3,RPL7,CFTR,SMYD3,RPL27A,HEXIM1,HSPA8,RAB5A,BAP1,PYM1,RPS28,EIF4E,G3BP2,AATF,STAU1,RPL4,MYC,RPL7A,NTRK3,MAPRE1,UBE2H,RC3H2,RPL37A,RPS12,PHF21A,RPS20,SEC61B,FAU,RPS3,PSPC1,CCNF,METAP2,RPL22,ESR2,VIRMA,MAD2L2,RPL19 |
| 8.000e-06 | -11.74 | TSNARE1 (t-SNARE domain containing 1) | protein interactions | 203062 | 36 | 23 | 19454 | 5460 |
LMNA,SDC2,CYB561,STX1A,ZDHHC15,MFSD14B,CNIH4,SNAP29,TM4SF19,TOP3B,NDE1,VEZT,YIPF4,HNRNPL,REEP4,DYNLL1,LEPROTL1,RIGI,JAGN1,TMX2,ELOVL4,RETREG3,TMEM229B |
| 8.004e-06 | -11.74 | Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | REACTOME pathways | R-HSA-936964 | 18 | 15 | 10285 | 3229 |
TBK1,CD14,IRF3,TLR3,TICAM2,UBB,SARM1,RPS27A,TANK,UBA52,TLR4,LY96,IRF7,PTPN11,TICAM1 |
| 8.015e-06 | -11.73 | CDK4 (cyclin dependent kinase 4) | protein interactions | 1019 | 276 | 111 | 19454 | 5460 |
IFI27,CCAR2,EGLN3,ANKRA2,HSP90AB1,PHB1,AK2,PSMD10,CDKN1B,ACTR3B,ZBTB16,CDKN2C,PCNA,UBE3A,IRF8,EIF1AX,CDK5R1,RAF1,E2F4,SOX2,H1-3,ASPM,PPP2R1A,ATP5F1B,TUBB,PAQR4,LMBR1L,PRMT5,CDC7,BRCA1,HSP90AA1,SP1,RIT1,H1-1,MYC,CUL3,CDKN2D,UFL1,CCND3,SKP1,RFC4,DUSP9,HSPA8,TERT,IL15RA,ANXA7,WDR77,LNX2,ZC3H14,PGRMC1,CDKN1A,FZR1,GRM1,TOP1,MAPRE2,PTPN1,RPRM,SMAD3,HRAS,RB1,CDK6,UBXN10,BECN1,NOL12,FGR,BMPR1B,KLHL32,COPS5,SERTAD1,EIF4EBP2,CNOT7,VTA1,RIGI,IGF1R,CAMK1,FBXO8,BIRC5,OTX2,TMEM126A,TP53,CDK4,MAP2K3,EGLN2,DDAH2,CCNF,STUB1,PSMA6,PTEN,ZNF655,SPOP,SMAD2,EPHA2,STK11,UBE2H,SLC25A1,AKT1,AGAP2,NF2,PIAS1,OGDHL,RPA3,MRPS34,CDK1,RPA2,SSR1,CNTN2,HEXIM1,MET,CCND1,KDELR2,CCNA2 |
| 8.076e-06 | -11.73 | PXMP2 (peroxisomal membrane protein 2) | protein interactions | 5827 | 279 | 112 | 19454 | 5460 |
ARCN1,VAPB,RAB6A,TOMM22,TOR1AIP2,PGRMC1,FBXL4,UFL1,GPM6A,NSFL1C,SLC15A1,TXNL1,AKAP1,EXD2,SCFD1,SERPINH1,LMNB1,PSMD1,VEZT,RAB11A,ATP6AP2,ESR2,PSMD4,ATP5F1B,REEP4,EDNRA,LMBR1L,CRELD1,RPN1,STIM1,AQP3,LPAR6,FAF2,NUDCD3,MACO1,STBD1,SAR1B,EMC8,USP30,UBE3A,PEX3,VCPIP1,CDK5RAP3,PPIB,DDRGK1,PDIA3,SIVA1,UBXN6,PTDSS1,MARCHF5,CACYBP,PEG10,NUP35,PEX13,STX5,PDCL,LEMD3,SLC12A2,HSP90B1,GOLGA5,USE1,RABL3,ARHGAP1,SEC22B,UBA52,TMEM209,SLC5A6,YKT6,SQSTM1,MAVS,MTDH,SLC39A9,TEX264,MME,RAB29,CALU,CISD1,ARFGAP3,GORASP2,HMOX2,SLC7A8,SLC11A2,GANAB,SLC1A1,STUB1,PSMC3,UBIAD1,DDX39A,LBR,MTARC2,PREB,CCDC47,UBL4A,SNAP29,FKBP8,HUWE1,CD80,STX18,RAB1A,OSBPL8,POR,ESYT1,SMIM12,HM13,CALR,TMEM199,TMPO,LMAN1,DNAJC1,SRPRA,PTPN1,CAMLG |
| 8.084e-06 | -11.73 | CTSB (cathepsin B) | protein interactions | 1508 | 232 | 96 | 19454 | 5460 |
PDIA3,CST3,PTDSS1,CSTA,AK2,HNRNPD,RNF139,PHB1,XPO5,SPINT2,GATD3,SPTAN1,AASDHPPT,RMND1,OS9,RAF1,H1-3,ACTN4,ERLIN2,EZH2,RPN1,MYO1B,BAG2,ERP29,MMP9,IGF1,S100A10,MYC,PMPCA,CUL3,AK3,SLPI,MYO6,SERPINH1,ESR2,APEX1,CLIC4,LAP3,CNPY3,CDKN1A,MAP2K1,APOC2,ANXA7,LUM,HSPA8,RNF5,KARS1,CALR,BGLAP,TMOD2,EEF1AKMT3,MARCHF4,LMAN1,FAM118B,TP53,GLRX5,ARPC3,SOD2,RNF8,SLC25A11,ERO1A,ABCE1,PRDX4,MPST,CTSD,ATP5F1A,GMPS,SDF2L1,DNAJC10,NRP1,STK11,REN,FXN,CALU,CCNF,GXYLT1,GANAB,CTSB,IRF2BP1,TXNDC12,RPGRIP1L,ST7,HSP90B1,IDH2,RNF103,GSTP1,SCLT1,BAP1,CSTB,NBN,GID8,HSPB2,MTDH,AIF1L,TTR,RGS2 |
| 8.120e-06 | -11.72 | IL17B (interleukin 17B) | protein interactions | 27190 | 77 | 40 | 19454 | 5460 |
RPLP2,PRKRA,MYEF2,ENO2,RPL32,RPL8,SURF6,RSL24D1,KBTBD6,DKC1,ZNF668,CALR,RPF2,DICER1,MPHOSPH10,FTSJ3,WDR12,TTL,RPL3,MKLN1,HNRNPA2B1,DCTN6,NKRF,RPL27,TMEM160,HSPA5,RPL17,STAU1,NUP42,RPL4,NOP53,RBMS2,RPL29,MAK16,RPL18,RPL26L1,RBM34,IPP,GLE1,LLPH |
| 8.120e-06 | -11.72 | Htt (huntingtin) | protein interactions | 15194 | 77 | 40 | 19454 | 5460 |
UQCRC1,STXBP1,CD59,COX6C,NDUFS3,GNAZ,CYC1,CCT8,SEPTIN7,HSD17B10,CNTN1,NPTN,CHCHD2,PHB2,GPM6A,VDAC1,COX6B1,NDUFB10,DNAJB2,HNRNPC,COX5A,DIRAS2,YWHAG,SYP,STX1A,SLC6A1,MDH1,PLP1,UQCRC2,VDAC2,ENO1,NEGR1,SYT2,GNAO1,THY1,SNAP25,PRNP,UQCRH,GNB1,SLC25A12 |
| 8.130e-06 | -11.72 | CDC37 (cell division cycle 37, HSP90 cochaperone) | protein interactions | 11140 | 623 | 224 | 19454 | 5460 |
RIT1,ILK,NTRK3,HSP90AA1,PFDN2,YWHAZ,LMNB1,BRCA1,PSKH1,MAP3K21,RIOK2,CUL3,ACTB,TAB1,TUBB,PRDX2,SNRPD1,PSMB7,TIMM13,SKP1,UNC45A,PXMP2,IL1B,FBXW4,AHSA1,STX1A,FATE1,MAP3K14,HNRNPA1,PRDX1,EGLN3,CGGBP1,DIRAS3,CCAR2,MAP1LC3A,WDR6,SNRPE,PPID,PPP2R1A,GABARAPL1,RAF1,CKS1B,AHCYL1,GCA,CDK20,G3BP1,TESK2,CDKN2C,HNRNPA2B1,SLC25A5,MAP3K11,REEP6,CCHCR1,STK11,EPHA2,PIM2,CHORDC1,AR,CSK,STK38L,YES1,COPE,TXN,ACAT1,MSN,UBE2I,PPM1M,GSK3A,CTTN,TUBA1B,EIF2AK2,STUB1,CCNF,OPTN,MET,LSM2,HSP90B1,CDK1,CDK7,GABARAPL2,ATG16L1,GABARAP,RPL4,SQSTM1,FLCN,PRKCB,PRPF4,PRIM2,RPA3,FGR,STYK1,DNAJC7,CDC37L1,MOV10,CDK9,MAP2K6,ZBTB26,ACTR2,TIMM8A,THAP1,MAP2K3,MAP1LC3B,EEF1A1,TBK1,PTGES3,PSEN1,TTC4,CAMK2G,IGF1R,NTRK2,CDKL2,PSMD14,RPS6KA4,LAMTOR1,THAP7,ATG101,CDKN2D,MYC,APEX1,PPP5C,PRMT5,NFKBIB,CKS2,NCOA5,MAP2K1,ADSS2,EDEM3,NUP62,DDX5,STK26,AKAP1,HSPA8,DDX39B,YWHAB,STAMBPL1,AGR2,FKBP4,AK2,IKBKB,GAS8,STK4,CTNNB1,YWHAG,MRPL9,YWHAH,RPL6,MAPK4,PRKX,MDFI,HSP90AB1,TTC9C,EIF2S1,HOMER3,MOB3C,ZRANB2,PNMA2,EEF2,TRAF2,CBLL1,CCAR1,SSNA1,ZBED1,EPHA4,KRAS,EWSR1,CDK5,RPAP3,CYP2C9,UBE2H,SNX5,EXOSC1,CEP70,GPRASP3,AKT1,AKT3,SRC,BCCIP,PRKCE,MAP3K3,KCTD9,TRIM54,ZNF655,PSMC5,CSNK2B,FKBPL,PRKCA,UBE2M,HEXIM1,FGFR1,SAMM50,RPA2,CRYM,CFTR,SMYD3,HSPA5,FTSJ1,TNFAIP1,BTBD10,BAP1,GRAMD2B,USP15,RPS2,MZT2B,CSNK2A1,LMAN1,EPHB6,CHGA,RPS27L,CDK6,MGME1,ITK,AIP,PDE9A,SBK2,TNNI3K,DISC1,CDK8,ACTR1A,CDK4,FKBP8,HNRNPK,POC1B,PSME1,DDR1 |
| 8.160e-06 | -11.72 | carbohydrate derivative biosynthetic process | biological process | GO:1901137 | 589 | 222 | 18204 | 5365 |
CYTL1,GXYLT1,CHST11,NDUFA2,DOLK,ATP5PF,ALG11,TECR,ADCY2,GLCE,AKR1A1,SLC25A10,B3GALT2,ATP5MC1,B4GALT7,ACACA,DCK,UGCG,CHPF,XXYLT1,DNPH1,B4GALT1,GALNT17,MPDU1,GALNT4,UAP1,PDHB,FKRP,GAL3ST1,NDUFA1,QNG1,IL1B,PXYLP1,NPR2,ATP5F1B,ATP5PD,PGAP2,PRPS1,NUDT2,TMEM106A,B4GAT1,UQCC3,CHST9,IGF1,GK5,ATP5MG,ST6GALNAC3,CRYL1,RPN1,AQP11,ATP5PO,PSEN1,B3GALT4,ST3GAL2,DTYMK,SRD5A3,B3GALNT1,MTAP,NDUFC2,GUK1,PRPSAP1,PIGW,NME4,NDUFS3,ST3GAL1,SLC35C1,NUS1,ADCY3,ATP6V1A,ALG5,GMDS,GFPT1,ADSS2,ELOVL7,AK2,DCAKD,NDST3,NDUFB7,UST,NDUFA12,GAL3ST4,GNPNAT1,UCK2,DAD1,UPRT,PNP,ATP5F1A,HAS3,NDUFS8,HS3ST5,PMM2,FUT1,OST4,DLAT,NDST1,TYW5,NANP,HEXA,NDUFB6,PGAP3,SLC25A1,TUSC3,STOML2,ACSL4,DNAJC30,MMUT,HACD2,FUT8,POMT2,SDHB,UMPS,TMEM59,ACAT1,CHST7,FAM20B,PDHA1,GALNT12,CHST2,ST8SIA5,FKTN,CSGALNACT2,G6PD,HS3ST1,GUCY1B1,PIGA,EXTL2,NDUFB5,B3GNT2,FUT9,ATP5F1D,ELOVL1,MGAT4A,TYMS,MGAT5B,BMPR1B,NPPC,DCTD,UCK1,ELOVL6,DPM2,NDUFA5,ATP5MK,NME2,TYW3,DPAGT1,GFUS,PPAT,GK2,CERK,ARFGEF1,FA2H,SHMT1,GALNT2,PPT1,GPAA1,UCKL1,PIGY,AK5,ST8SIA4,ELOVL4,LIPA,HS2ST1,STT3A,B4GALT6,GMPPB,MGAT1,NDUFB8,PAPSS2,HS3ST3A1,SDHC,ST3GAL5,GNPDA1,ALG2,PIGK,C1GALT1C1,MAN1A2,NDUFS6,SLC30A5,B4GALT3,EDEM3,BMPR2,CMPK1,ATP5F1E,AK3,GNPDA2,GCNT3,NDUFB4,HACD1,B4GALT4,RRM1,CHPF2,ATP5MC3,COX11,B3GALT1,ST3GAL4,TMEM165,SORD,MGAT4B,UGDH,NME1,NDUFB10,NDUFAB1,CHST1,EXT1,GXYLT2,ANGPT1,LARGE1,ACSS2,NDUFV2,CSGALNACT1,PGAP4,ATP5PB,ABCC5,CHST10,ELOVL3,PIGC,GALNT1,ST6GAL1,ADK,NDUFS2,CHST13,GMPS |
| 8.233e-06 | -11.71 | MRPS18B (mitochondrial ribosomal protein S18B) | protein interactions | 28973 | 288 | 115 | 19454 | 5460 |
EXD2,NGRN,PHB2,HSCB,MRPS7,BET1,SYK,DUSP14,TIMM29,MTG1,CCDC90B,TACO1,RPS9,RPL35,RPL10,CUL3,PMPCA,HNRNPAB,MTG2,AUH,MYC,MRPS25,NOA1,PSKH1,MCAT,RBM3,HSPD1,SRSF7,MRPS11,HINT2,EWSR1,MRPS17,RAF1,ZNF263,TULP3,SOX2,PDHA1,NFKBIL1,GATD3,RMND1,MRPS35,CLEC1A,MTRF1,DDRGK1,TRA2A,HNRNPA1,RHOG,MRPS26,LRP10,BAP1,RNF113A,GFM1,SQSTM1,HMGB1,NPM3,CRYZ,SEC22B,FGF13,RBMS2,KLF12,GRM2,SYS1,MRPS34,ZNF770,MTRES1,KLF4,HEXIM1,PSPC1,MRPS28,MRPS21,SRPK2,TUFM,PPP1CC,DEPDC1B,RC3H2,MRPS16,DNAJC19,UBE2H,IGF2BP1,MRPS18B,DNAJC30,MRPS33,RPL17,MRPS18C,MEPCE,FASTKD5,TP53,MRPL11,STRBP,METTL15,AURKAIP1,GFM2,COX4I1,ALYREF,SSBP1,MRPS9,SRP14,RB1,TRMT10B,PRR3,CGAS,CAND1,FZR1,MRPS23,ZBTB2,GRSF1,MOV10,KARS1,E4F1,CD81,SLC35A1,TMEM70,CHCHD1,SNRNP70,DNAJC4 |
| 8.287e-06 | -11.70 | chaperone-mediated protein folding | biological process | GO:0061077 | 74 | 40 | 18204 | 5365 |
HSPE1,CCT8,ST13,DNAJB2,CCT7,DNAJC24,CCT5,DNAJB6,TOR1B,TCP1,TOR2A,PPIB,PPID,FKBP4,HSPA8,DNAJC5,PFDN5,ERO1A,SDF2L1,DFFA,DNAJC7,HSPA5,PFDN4,CSNK2A1,FKBP2,CLU,PTGES3,CHORDC1,HSPB1,P3H1,CRTAP,HSPA14,DNAJB4,PFDN6,HSPB6,UNC45A,CCT2,PFDN2,HSPA13,PFDN1 |
| 8.287e-06 | -11.70 | DTX3L (deltex E3 ubiquitin ligase 3L) | protein interactions | 151636 | 62 | 34 | 19454 | 5460 |
JAK2,ESR2,CGAS,PRNP,STAT1,UBE2I,CCNF,NLRP3,UBE2H,PHF7,UBE2E3,H2AZ2,H2AC4,UBE2D1,GLOD4,AR,PPIB,UBE2E2,CUL3,UBE2K,UBE2D3,G3BP1,LCN1,JAK1,PML,RPA3,HGS,RPA2,H2BC11,SPG21,IFNGR1,UBE2W,NOTCH2,ATG16L1 |
| 8.287e-06 | -11.70 | IFIT1 (interferon induced protein with tetratricopeptide repeats 1) | protein interactions | 3434 | 62 | 34 | 19454 | 5460 |
MOV10,HNRNPC,SNRPB,PCCB,SNRNP70,HSP90AA1,IGF2BP1,IFIT2,SNRPD1,SNRPD2,TES,RPLP1,SNRPA1,SNRPD3,ACTB,CGAS,IFNA10,SNRPB2,TFEB,HSP90AB1,ATG16L1,ISG15,EZH2,ILF2,SNRPE,ACACA,SNRPA,PABPC1,HSPA8,PC,MAVS,EP300,GRPEL1,EIF3E |
| 8.349e-06 | -11.69 | RPL36AL (ribosomal protein L36a like) | protein interactions | 6166 | 297 | 118 | 19454 | 5460 |
MRPL52,RPL23A,RPL3,MRPS33,RPS13,SRSF12,MEPCE,RPL17,UBL4A,APOBEC3D,TAF1D,MAP2K3,IKZF5,RPL15,LLPH,RBM34,SRP72,MRPL51,H2AZ1,SRP14,MRPS9,KRR1,PRR3,RPL35A,RPS16,SEMA3C,RBM42,MDM2,SURF6,MRPL24,ZBTB2,E4F1,SNRNP70,MPHOSPH10,RPL10A,RPL27,PPM1G,HSPB2,RNF113A,RPS15,DGCR8,NPM3,NF2,MRPL40,FTSJ1,RPL4,AATF,UTP23,RPS14,MRPL10,FGF13,CFTR,MRPS34,ZNF574,RPL26L1,RPLP0,HEXIM1,RPS3,MRPL53,TNFRSF1B,EZH1,FGFBP1,GSK3A,PRKRA,RHOJ,RPL13A,CIAO1,RPL7A,RPL26,RC3H2,UBE2H,RPL31,MRPS11,H1-6,TRIM37,RPL28,RPS27A,H1-3,MAK16,RPS7,SKA3,FOLR1,RPL8,RPS10,LYAR,RPL7,WWP2,DDRGK1,MRPL18,AGR2,MRPS26,DICER1,UFL1,STAU1,FTL,MRPS7,RPL27A,H1-5,FGF17,NOTCH2,KLF3,ZNF22,LRRC1,RPL37A,MRPL13,SEC61B,RPL35,RPF1,ESR2,KBTBD6,RPL19,MYC,MRPL16,BTF3,ZCRB1,MRPS25,H1-1,RIT1 |
| 8.359e-06 | -11.69 | CLIC1 (chloride intracellular channel 1) | protein interactions | 1192 | 155 | 69 | 19454 | 5460 |
PPP1CC,NTF4,ST13,ACO2,HNF1B,MYC,UBE2H,GLOD4,SDF2L1,BRCA1,RHOB,ENO1,GGPS1,VIRMA,ESR2,NMI,CLIC4,NDUFAB1,CFTR,WDR77,NUP62,ATG16L1,DDAH1,GSTP1,ARCN1,RPA2,LMNA,IDH2,TXNL1,HSPA8,YAF2,PRDX6,RPA3,SOD1,BAP1,XRCC5,PDHB,GPC1,HDAC6,FRA10AC1,RIOX2,POLB,PSMD10,PPM1B,AGR2,RPLP1,HDHD3,NTMT1,PRNP,SOX2,ISG15,PGM1,RAF1,CMPK1,ATP5PB,NUPR1,EZH2,CAPZA2,HINT2,EWSR1,TAGLN3,HSD17B10,PRDX4,RIGI,SEPHS1,ALOX5AP,PSMA1,PSMA5,TRIM37 |
| 8.380e-06 | -11.69 | FUBP1 (far upstream element binding protein 1) | protein interactions | 8880 | 300 | 119 | 19454 | 5460 |
H2BC17,DDX23,HNRNPD,MAGOH,CRIP1,RAB32,PRPF19,RPL6,HNRNPA1,HNRNPL,TCP1,NUP35,THOC2,SIN3A,FUBP3,EED,PIR,NME1,PDHA1,PLD3,ACO1,KRAS,MAPK1IP1L,FOXP4,HNRNPA2B1,RBM27,BRCA1,CRMP1,THOC6,RIT1,MYC,CUL3,TOMM40,SNRPB,CAPG,CPSF2,MATR3,PRDX2,SNRNP40,PPP5C,ESR2,CPSF1,RPS9,LARP4B,LAP3,WDR77,ZC3H14,PRR13,FXR2,ARHGEF39,STAU1,MT2A,G3BP2,FOXP2,SNRPA,UPF3B,XRCC5,PPIC,SNRNP70,RPS2,FOXP1,MOV10,TLE1,COPS5,CD81,ATP1B1,RPS16,THOC1,PRNP,MDM2,CDK9,CDC5L,HRAS,SYNCRIP,ACTR2,TP53,PGM1,CDC40,KPNA2,ARF4,MDC1,SMN1,RAB1A,RPL3,ZC3H11A,HSD17B10,NIF3L1,CHORDC1,IGF2BP1,CASC3,RUNX1,NONO,AR,BUB3,VIRMA,CCNF,OPTN,PRKRA,PTEN,RPA2,RPRD1B,ZNF326,HNRNPH3,TFIP11,LUC7L3,SPR,CCNH,MAEL,CERS2,RPS15,MRPL41,GRPEL1,BCL6,SNCG,RPA3,SOD1,BAP1,PML,ARPC2 |
| 8.403e-06 | -11.69 | PHGDH (phosphoglycerate dehydrogenase) | protein interactions | 26227 | 342 | 133 | 19454 | 5460 |
KBTBD4,H2AX,EEF1A1,TFCP2,SURF4,NECAP1,IK,RAD23B,CASK,MAP1B,FAF1,ATP5PF,HAPSTR1,HUWE1,THRAP3,HSPE1,MEPCE,FBXO25,MDC1,COX5A,PGAM1,HDAC6,AIFM1,UBE2N,NUDT9,KCTD15,CAND1,CDK9,TMPO,CDC5L,ATG16L1,CCND1,UQCRC1,CDK7,CFTR,RPA2,JUP,FGFR1,GRM2,UBE2M,HEXIM1,BAP1,RPA3,H2BC12,SQSTM1,RNF113A,PDHB,FBXW7,CHMP2B,UQCC3,HSPA5,SMARCA5,NDUFAF2,MORF4L1,FBXO7,ATP5F1A,AR,SPOP,OAT,CDC73,UBE2H,TUBA1B,ALB,NDN,VIRMA,B3GNT2,TOP3B,RAF1,ETFB,NCSTN,ISG15,SOX2,H1-3,EZH2,CHMP4C,MOB3C,HSPD1,PABPC1,RPAP3,KRAS,ETFA,RPS27A,SSRP1,WWP2,XPO1,HNRNPA1,DDRGK1,TRA2A,CTNNB1,CSTA,AGR2,BCL2L1,FOLR1,SRSF1,PHB1,TYMS,EGLN3,SRSF10,NUP35,ADNP,PIH1D1,CSNK1A1,MYL6,DDX39B,HDAC5,HSPA8,EP300,RNF5,SLC31A1,UFL1,PHB2,STAU1,SAP18,MYC,HNRNPC,CUL2,LDHB,CUL3,BTF3,BAG3,BRCA1,COP1,CCDC25,SLC7A11,LMBR1L,S100A6,SMU1,STAT1,ATP5F1B,ACTB,GDPGP1,CHCHD3,MAD2L2 |
| 8.440e-06 | -11.68 | TMEM161A (transmembrane protein 161A) | protein interactions | 54929 | 67 | 36 | 19454 | 5460 |
SLC2A1,P2RY1,PTGER4,OXTR,ATG9A,MYC,CSK,TM9SF4,HDAC6,CCR2,TMED9,NR1H2,ARMC6,GPR37,ELK1,ESR2,APEX1,CCNF,HRAS,S1PR4,CHRM5,GPR173,SEC61B,RPN1,STOM,GPR35,RAF1,CCDC47,OTULINL,YIPF5,SEC62,KRAS,SLC6A8,ATP5PF,TSPAN15,VIPR1 |
| 8.459e-06 | -11.68 | PRKCI (protein kinase C iota) | protein interactions | 5584 | 312 | 123 | 19454 | 5460 |
CCNF,OPTN,GAB1,MRPL53,CSNK2B,PSMC5,PRKCE,ADRM1,SLC25A4,RHOJ,SRC,SMURF1,RAB2A,DNAJC5,PRKACB,STK24,UBE2H,RPA3,RHOU,SQSTM1,SMC4,GREM2,IL1RAP,TTR,FABP4,BRIX1,EDDM3B,GABARAPL2,CDK7,MRPL10,CDC42,SSR1,RPA2,MRPS34,ACACA,PARD6A,PRKCA,MRPS9,SSBP1,HRAS,RAC2,FZR1,CAV1,DPP4,GAPDH,CSNK2A1,IL17F,USP15,NTRK2,KPNA2,TOLLIP,HUWE1,PSMA5,ABHD10,MRPS18C,TP53,MRPL47,MAP1LC3B,DUSP1,CASK,TRAPPC13,NFKBIA,PNMA1,BAD,MRPL23,ESR2,GNB1,SELL,PSMB6,CUL3,PSMD1,RHOB,MRPS25,YWHAZ,NTRK3,HSP90AA1,TMEM160,HSPA8,STAU1,PXMP2,RPL27A,MRPL12,PPP1CB,MAP2K1,FRS3,CTBP1,MRPS18A,SLC25A3,PPP2CB,MAP1LC3A,MAGED2,RHOH,SNRPD3,KIF3B,HNRNPL,TMEM208,MRPS35,DDRGK1,YWHAH,YWHAG,XPO1,ATG7,PPM1B,IKBKB,DDX23,RHOG,HSPB1,YWHAB,RASSF8,SLC25A5,BAG2,ZNF609,KRAS,PSMD12,MCM6,DHX38,ARFGEF1,RAF1,GABARAPL1,ACTN4,PPP2R1A,RAB4A,RND3 |
| 8.462e-06 | -11.68 | NEMF (nuclear export mediator factor) | protein interactions | 9147 | 90 | 45 | 19454 | 5460 |
RAF1,EZH2,SNRPG,DDRGK1,CYP4V2,IFI16,KXD1,COX5A,WWP2,RPL23,SMAD4,DHX15,HNRNPL,RPS16,HYPK,PAFAH1B1,HAUS2,HSP90B1,EXOSC4,EP300,BAP1,ORMDL1,CERS6,PSENEN,UFL1,STAU1,FBXW7,PSMD1,MCM4,CDC16,ZBTB38,STK11,POLR1B,EIF2S2,SEC61B,CCNF,OPTN,TCEAL7,RPL10,RPL19,COPE,PSMD4,ZNF622,SPCS1,MED17 |
| 8.462e-06 | -11.68 | CPOX (coproporphyrinogen oxidase) | protein interactions | 1371 | 90 | 45 | 19454 | 5460 |
HSPA5,HNRNPA0,NUCKS1,PHB2,SLC25A51,TWNK,HSPA8,SOD1,EIF4B,NDUFAB1,PARL,ACTB,DYNLL1,CCNF,HTRA2,CCT2,BRCA1,ATP5F1A,CTSD,CARS1,PSMA4,CUL3,IMMP2L,HNRNPDL,HNRNPK,PCNA,PPP1R12A,RAB1A,SFXN1,APOO,EEF1A1,RRM1,TXNRD1,CACYBP,CCT7,COX14,HSP90AB1,SLC25A12,PLGRKT,LDLR,NUDT9,AIFM1,COX4I1,UBE2G2,ATG7 |
| 8.473e-06 | -11.68 | MRPL12 (mitochondrial ribosomal protein L12) | protein interactions | 6182 | 327 | 128 | 19454 | 5460 |
EIF5B,MRPL17,MRPL40,MRPL41,MRPL20,BAP1,SOD1,SEPTIN6,CCDC65,GFM1,IDH2,TFB1M,RPL26L1,HEXIM1,MTRES1,POLR1D,CD2AP,MRPL10,SUCLG2,MRPL53,ACOX1,MRPS28,PTPMT1,MSN,RC3H2,DNAJC19,UBE2H,RNASET2,RPL7A,MORF4L1,NTAQ1,TUFM,H3C1,FASTKD5,MRPL22,MEPCE,MRPL52,SLC25A10,SEPTIN7,CBX3,GFM2,MRPL33,MRPL51,MRPL49,TBK1,MRPL11,MRPL47,GTPBP8,AURKAIP1,METTL15,FZR1,CAND1,MRPL50,THOC1,MALSU1,CDK9,MRPL24,RPL12,SSBP1,MRPS9,UBE2N,CHCHD1,TMEM70,RPS2,GRSF1,HSCB,UFL1,ADRB2,MRPL57,CMAS,FOXP2,NGRN,EXD2,COX6A2,SAT1,MRPL34,MRPS18A,MRPL12,MRPL23,TAX1BP1,SNRPB2,RPL19,TACO1,DLST,MTG1,CCDC90B,MRPL13,PPP1R16A,RIT1,AUH,MYC,MTG2,CUL3,MRM2,PMPCA,MRPL16,KRAS,UFM1,VDAC1,FOXP4,PREPL,HSPD1,RBM3,LSM14A,BCKDK,HINT2,COX8A,PDHA1,OXNAD1,RPL18,SOX2,OS9,RMND1,MTERF2,THOC2,PHB1,RPLP2,GATD3,AK2,RHOG,MRPL18,MRPS26,HNRNPD,RPL23,MTRF1,PDIA3,MRPL9,DDRGK1 |
| 8.491e-06 | -11.68 | - | gene3d domains | 2.30.30.100 | 25 | 18 | 14470 | 4137 |
LSM14A,EDC3,GEMIN7,SNRPG,LSM6,LSM10,SNRPN,SNRPD1,LSM5,LSM2,SNRPB,SNRPD3,LSM3,LSM4,LSM8,SNRPE,LSM14B,SNRPD2 |
| 8.516e-06 | -11.67 | IMMP1L (inner mitochondrial membrane peptidase subunit 1) | protein interactions | 196294 | 241 | 99 | 19454 | 5460 |
TIMM29,TIMM13,PRDX3,MTX2,NUP62,NDUFA5,PIH1D1,ZER1,VPS18,SELENOO,POLA2,NDUFS2,PYCR1,ILK,CBR3,KIAA1191,DLST,TACO1,PARL,NDUFAF4,CHCHD3,TIMM21,NUP37,POLR2C,FAM136A,NDUFA12,NDUFS6,PRKAG1,NUDT19,RPAP3,OPA3,RINT1,HSPD1,NDUFB5,IMMP2L,USP30,NDUFV2,PDIA3,NDUFB8,HAX1,UQCC6,AK2,POLR2L,CCT7,NDUFS8,PEG10,RAMP3,POLR1D,TIMMDC1,MYL12B,PCK2,CYC1,SAMM50,COX6C,TMEM126B,GFM1,POLDIP2,TSPAN5,NME4,PYCR2,NDUFB10,NDUFAF2,CALU,CHCHD4,SGTA,CHCHD6,PSPC1,QNG1,PDCD5,TIMM8A,BCS1L,APOO,NDUFA2,FAM162A,TBK1,TMEM126A,ATP5PB,SLC25A24,GEMIN7,PPP4C,NDUFS3,ACADSB,GPD2,TMX3,CLPB,SFXN1,PPP1R12A,VPS16,HSPE1,CAMK2G,CSNK2A1,COX5A,DNAJC7,SMIM12,COX4I1,AIFM1,SLC25A12,PLGRKT,TOMM70 |
| 8.529e-06 | -11.67 | MRPS21 (mitochondrial ribosomal protein S21) | protein interactions | 54460 | 122 | 57 | 19454 | 5460 |
ATP5F1A,CUL3,MYC,MCAT,RIT1,MRPS25,RPS9,CCNF,RPL10,RPL35,NDUFAF3,RBMS2,GTF2H4,ACACA,HEXIM1,MRPS34,GFM1,SQSTM1,PGK1,EXD2,PSMC1,HMGB1,HSCB,NDUFS2,TRA2A,RPL6,LAMTOR2,MOV10,GRSF1,MRPS26,SNRNP70,SKIC8,RPLP2,PRR3,TRMT10B,SRSF1,SRP14,MRPS9,MRPS23,MYL12A,RBM42,KCTD10,FZR1,CAND1,METTL15,APOBEC3D,AURKAIP1,CHMP4C,MRPL36,MRPS11,MRPS18B,HSPD1,MRPS17,FASTKD5,MEPCE,MRPS18C,KRAS |
| 8.558e-06 | -11.67 | TUBA1B (tubulin alpha 1b) | protein interactions | 10376 | 455 | 170 | 19454 | 5460 |
SMAD2,EPHA2,RC3H2,CHORDC1,SPOP,RUNX1,MORF4L1,RSPH1,CSK,VIRMA,SRPK2,SRC,PDCD5,DEK,CEP97,PRKCE,ARMC6,NDN,KCTD9,PTEN,UBASH3B,MACROH2A1,PRSS8,OPTN,FKBPL,HEXIM1,UBE2M,FGFR1,TCP11L1,SMYD3,CFTR,GABRA1,CDC42,UBA52,PSMC4,ATG16L1,FBXW7,RNF113A,SQSTM1,FLCN,INPPL1,BAP1,RHOU,USP15,BRD3,MAP4,CD247,SHC1,SNRNP70,TUBG1,HDAC6,CD81,SNAP91,COPS5,SLAIN2,CDC5L,CDK9,TOMM70,TES,RCHY1,CD274,SSBP1,EFNA3,RNF8,RAD1,STARD13,CAPN2,TFCP2,MAP1LC3B,MAP2K3,CCT5,UBL4A,MEPCE,PSEN1,TCP11L2,SLC6A3,LTA,PPP1R12A,MAP1B,RIT1,DNAJB6,PFDN6,PFDN2,SP1,PFDN4,RHOB,PSMD14,CCT2,PSMD1,HNRNPC,MYC,APEX1,TOM1L1,UBE2V2,TUBB,SIAH1,SNRNP40,AP2M1,ZMYM2,NFKBIA,PIH1D1,VAPB,AGTRAP,KCND3,FBXL4,EEF1G,UFL1,SRSF2,PSMA3,TERT,HSPA8,SF3B1,NMRAL1,HSPB1,PPP3CA,VCPIP1,CSTA,RHOG,DDRGK1,HNRNPA1,XPO1,PFDN5,LAMP2,UBXN6,IFI16,PIK3R1,CCT7,PPIA,ELK1,EGLN3,SUMO2,TCP1,RHOH,AFTPH,BRD9,COPS2,MAP1LC3A,EED,PHB1,FOLR1,RHOBTB1,RPL18,MTMR2,EZH2,TUBB4B,KIF2A,TNPO2,LGR4,ERLIN2,SOX2,FAF2,ISG15,TUBA1A,ASPM,SUPT5H,ERRFI1,B3GNT2,AHCYL1,PFDN1,PIWIL1,VDAC1,RUVBL1,TRIM37,RBBP7,KRAS,TNF,UBE3A,RUVBL2,PCNA,CCT8 |
| 8.559e-06 | -11.67 | HRAS (HRas proto-oncogene, GTPase) | protein interactions | 3265 | 712 | 252 | 19454 | 5460 |
TMEM237,RAB11B,WDR44,CACYBP,DIRAS3,MPP1,SPTAN1,SNX17,XPO5,DNM2,LRRC57,RHOG,PIK3R1,UBXN6,FLOT1,RPS27A,RASGRP3,SEMA4C,GPSM3,PLCB1,PLA2G4B,PLSCR1,SNRPE,PLD3,DHRS3,STX12,VAMP2,IFNGR1,DCUN1D3,TULP3,MAPK10,DLG3,RAF1,MARCKSL1,ARFGAP1,TNPO3,CHP1,CHCHD3,UMPS,THBD,AP2M1,SLC30A7,FZD6,CLDN3,SLC23A2,SLC7A11,NTRK3,RHEB,PKP4,CUL3,NIBAN2,CDC123,STX7,RP2,NPTN,MLH3,SLC35F2,TTC1,TMEM185A,CLDN1,RABAC1,DUSP9,MCRIP2,TBC1D24,ANXA7,RAB6A,DUSP22,EHD1,RGL1,PLSCR4,FAM234A,WDR77,CAV1,PRNP,ALCAM,CDCA3,MAP2K6,EHBP1,HRAS,TIAM1,CD9,MED21,DAG1,RAB23,HM13,CALR,RELL1,MOV10,MSH6,ADD2,PSEN1,CTNND1,WASL,RNF115,SNAP23,CCNY,SEPTIN7,DLG1,RAB1A,DHRS7B,PDLIM4,PDE6D,MRPL49,FNTB,SLC29A1,HINT3,PPIF,FERMT2,YES1,SNX3,MGST3,F11R,MSN,DTYMK,SLC11A2,CTNNA1,SCAMP2,OPTN,VAMP3,GAB1,STK11,EPHA2,BRAP,DEPDC1B,RALB,CDC42EP4,DESI1,FBXW7,SLC7A1,YKT6,NF2,CERS2,ITGA2,SLC2A3,LRRC8D,SHOC2,MET,SLC12A2,CTDSP1,AP1AR,CNP,PIP5K1A,SEC22B,VAMP7,CORO1C,PTK7,IL3,TNIK,RAB31,PCDH9,CBL,DUS4L,EXOC1,CTNNB1,OLR1,PPFIBP1,RAB5C,PAK6,SLC35A2,VAMP8,ROCK2,SLC20A2,EPHA4,KRAS,EFNB1,PIK3CG,RABGGTB,TMEM87A,GNAQ,CCR1,ARFGEF1,PRMT5,SLC38A1,ATG3,LAMTOR1,GCC1,SLC1A3,RALGAPA2,CXCL1,EPS8,PACSIN3,GOSR1,RAB5A,BMPR1A,FDFT1,CAV2,MAP2K1,USP6NL,TLR6,ANKRD34B,SLC38A2,PLSCR3,FCHO2,ADD1,MCL1,SLC39A10,RAP1B,SYNCRIP,ITGA6,ACSL4,SMAD4,PLEKHO1,RIT2,SCML1,NEDD8,RAB27A,ABCE1,SOS2,RAB13,SLC16A1,ATP2B4,BMPR2,TMEM165,TFRC,PIK3CA,EXOC3,PLAAT3,UBIAD1,CENPM,CDK4,TP53,SRC,ROCK1,DAPK1,RALA,TRAF7,NECTIN2,SNX5,ATP1A1,ENDOD1,TLR9,RAP2C,STXBP6,SPOP,SNX14,GORASP2,ARHGAP21,RGL2,NDUFAF2,PSMB2,PIP4P1,STK38,LCP1,TLR2,ITM2B,SEPTIN6,GRAMD2B,CSNK1G3,HECTD1,WWP1,CDC42,SPTBN1 |
| 8.561e-06 | -11.67 | G beta:gamma signalling through PI3Kgamma | REACTOME pathways | R-HSA-392451 | 48 | 30 | 10285 | 3229 |
GNG7,GNB4,IL3,GNB1,SHC1,GNG12,IL2RA,GNG2,IL5,GNG5,GNG11,GNG10,IL2,AKT2,GNG13,PIK3CG,AKT3,AKT1,GNG3,PIK3CA,JAK2,IL2RG,PIK3R2,CSF2,PIK3R3,GNGT2,IL2RB,PIK3R1,GNB3,JAK1 |
| 8.610e-06 | -11.66 | regulation of amyloid precursor protein catabolic process | biological process | GO:1902991 | 55 | 32 | 18204 | 5365 |
ROCK1,CSNK1E,GSK3A,MIR107,MIR29A,CHRNA7,LRRTM3,EFNA3,IGF1,SPON1,TNF,MIR29C,FKBP1A,MIR455,MIR24-1,EPHA4,MIR298,MIR339,ROCK2,IFNG,PRNP,SP1,NTRK2,AGER,MIR361,IFNGR1,PICALM,MIR153-1,MIR186,CLU,RTN4,MIR206 |
| 8.634e-06 | -11.66 | DDX20 (DEAD-box helicase 20) | protein interactions | 11218 | 212 | 89 | 19454 | 5460 |
COMTD1,UBL4A,TP53,CD2BP2,SIGLECL1,GEMIN7,DHX9,LSM4,PSEN1,SNRPG,SMN1,COPS5,SNRNP70,SYNCRIP,FA2H,FZR1,SNRPN,HCST,FAXC,CFTR,P2RY12,RPA2,LSM2,GRM2,BAP1,RPA3,SIRT7,FBXW7,CIAO1,TIA1,GEMIN8,RC3H2,UBE2H,DCLRE1C,CCNF,SRP54,PHAX,STAT5A,B3GNT2,TOP3B,RAF1,HDAC11,POLR2C,SNRPE,OTULIN,EWSR1,KRAS,P2RY10,DDRGK1,RB1CC1,HAX1,POU5F1,DICER1,SIN3A,PHB1,SNRPD3,EGLN3,CCT7,MTX2,CRYAB,MFAP1,SNRPA,HDAC5,HSPA8,NPTN,UFL1,HSCB,PHB2,STAU1,COIL,MYC,GPR17,CUL3,SNRPB,MCM3,PSKH1,CCT2,MYO6,DCAF4,COP1,RIT1,SCN2B,BAD,LMBR1L,SNRPD1,SNRPD2,SNRPB2,ESR2,PRRC2A |
| 8.643e-06 | -11.66 | MDC1 (mediator of DNA damage checkpoint 1) | protein interactions | 9656 | 409 | 155 | 19454 | 5460 |
ZNF207,DNTTIP1,DPY30,BABAM1,IFI16,HMGA1,CDH13,CDC23,EED,SRSF1,SIN3A,SUMO2,LYAR,GTF2E2,RPL29,TOP3B,SSBP3,POLR2C,SMARCB1,CHMP4C,BAG2,EWSR1,RFC2,VDAC1,ASF1A,SNRPB,CPSF2,SMARCE1,RFC5,PYCR1,EPS8,HNRNPAB,HNRNPC,DSN1,MYC,USP13,CREBBP,BRCA1,YWHAZ,ANAPC2,MCPH1,RMDN3,PELO,DLST,MIDEAS,VDAC2,PHF12,ESR2,POLR2B,CHCHD3,MAD2L1,TRIM29,TAX1BP1,SNRNP40,TAGLN2,PSMD4,CAVIN2,ESAM,CRYAB,CTBP1,EP300,SPECC1L,XRCC5,SMARCD3,DDX39B,RFC4,STAU1,RADX,PHB2,TPM3,MPG,CSNK2A1,COPS5,RBM17,CENPP,USP15,BRD3,TOPBP1,OSBPL8,SMCHD1,TNKS,ETV6,CDC5L,ZBTB2,MDM2,MYL12A,RPL35A,FZR1,EXOSC8,MAP1LC3B,H2AX,TP53,HINFP,NUPR1,RNF8,PHC1,BIRC5,ILF2,NECAP1,CHAMP1,CDK8,CBX3,MLC1,SLC25A11,SMN1,MDC1,CAPZA1,RIGI,TNKS2,FGF12,VRK1,NSMCE3,THRAP3,H3C1,USP14,AR,DEPDC1B,PYCR2,VAMP5,CDC16,CDKN2AIP,ANAPC4,PTEN,SEC61A1,PRKRA,ENO1,EIF4A3,LIG3,INPP5K,SRPK2,CDC20,COPE,H2AB1,SF3A1,CPSF4,RAG1,SSR1,GHITM,RPA2,LMNA,WRAP53,LSM12,MIS12,ANAPC16,SIRT7,NBN,PML,BANF1,RPA3,CLU,PIAS1,OIP5,NUCKS1,DGCR8,PDHB |
| 8.672e-06 | -11.66 | MRPL20 (mitochondrial ribosomal protein L20) | protein interactions | 55052 | 172 | 75 | 19454 | 5460 |
MRPL13,CCDC90B,TACO1,CCNF,ZNF22,MRPL53,RPL10,RPL19,VIRMA,RPL35,RPL13A,MRPL23,TUFM,RPL26,EPS8,PMPCA,MYC,USP13,AUH,MTG2,UBE2H,RIT1,DNAJC19,AKAP1,GFM1,MIS12,NGRN,FTL,MRPL41,HSCB,NPM3,RBMS2,MRPL12,MRPL10,RPL27A,SLC25A3,MTRES1,MRPS18A,GATD3,FAHD1,EED,PRR3,SSBP1,SDHB,MALSU1,MRPL50,MRPL9,GRSF1,MTRF1,MRPS26,TMEM70,SNRNP70,CHCHD1,MRPL18,RHOG,COX8A,SRSF7,HINT2,LSM14A,HSPD1,MRPL52,UTP25,RPL17,FASTKD5,KRAS,H1-6,METTL15,APOBEC3D,MRPL47,MRPL11,MRPL51,RPL18,MRPL33,GFM2,PDHA1 |
| 8.672e-06 | -11.66 | NHERF1 (NHERF family PDZ scaffold protein 1) | protein interactions | 9368 | 172 | 75 | 19454 | 5460 |
GPC1,YTHDF1,ADRB2,NF2,ABCC2,BCL2A1,STX7,CD40,MME,RNF113A,APPBP2,OPRK1,GRM2,FGFR1,CDK1,LDHAL6B,SLCO1A2,CNDP2,HEXIM1,PRKCA,ARL15,CAPN1,ATG16L1,NEK7,CFTR,SNRNP27,YES1,PTPRQ,IREB2,RPS3,PTEN,MSN,PLCB2,RHOB,YWHAZ,SLCO3A1,CKB,MDH1,VAMP5,LDHB,RAB11A,ACO2,AKT1,RNASET2,ATP5F1A,CSE1L,ZBED1,RIGI,PABPC1,GNA11,PALM2AKAP2,HSPD1,PLCB1,NHERF1,GNAQ,OTULIN,PPME1,SLC4A8,KCTD3,G6PD,ASNSD1,SRSF1,SOSTDC1,DLGAP4,AGR2,SMAD4,BCL10,P2RY1,RPL23,YWHAB,UBFD1,CDKN1B,PDIA3,AP5S1,CTNNB1 |
| 8.683e-06 | -11.65 | generation of precursor metabolites and energy | biological process | GO:0006091 | 356 | 143 | 18204 | 5365 |
UQCC3,RPIA,ADIPOQ,STBD1,UCP2,PPP1R3C,COX4I2,COX6A2,COQ10B,ATP5MG,SLC25A4,ATP5F1B,ETFRF1,MT3,ATP5PD,NDUFA1,LDHA,UQCR11,PGAM1,AKT1,ACO1,PDHB,NDUFA5,SDHAF2,PFKFB2,FKRP,PHKA1,UGP2,CYC1,KGD4,ATG3,MCHR1,NDUFB5,ATP5F1D,PPP1CC,COX8A,TAFAZZIN,THTPA,GSK3A,IDH1,ADRB3,PDHA1,G6PD,NDP,ATP5PF,PID1,SDHB,COX4I1,ATP5IF1,VPS54,BPGM,NDUFA2,ACAT1,RPE,SLC25A14,PYGB,GYS1,COX7B,IMMP2L,ATP5PB,STOML2,UQCRH,NDUFS2,IDH3A,SUCLG2,GBE1,PYGM,TP53,NDUFB6,PGM1,NDUFV2,IER3,PPP1R1A,COX10,ALDH1L1,SOD2,DLST,LEPR,UQCRC1,COX6B1,POR,AKT2,NDUFS8,PTGES3,NDUFB10,ATP5F1A,RB1CC1,COMT,NDUFAB1,HTR2A,ENO1,DLAT,NDUFA12,IL6ST,NDUFB7,GNMT,ACO2,ENO2,GPD2,WDR45,CYB561,LEP,IDH2,GFPT1,COX17,COX6B2,PPP1CB,UQCRC2,NDUFB4,GAPDH,ETFB,COX5A,SDHAF4,UCN,GABARAPL1,NDUFA4,ATP5F1E,OXCT1,IDH3B,NDUFS3,IREB2,GNPDA1,SDHC,NDUFS6,NDUFC2,SLC25A12,PHKB,OGDHL,COX7B2,PGK1,ATP5PO,PHKG1,FXN,LIPA,UQCRQ,ACOX1,MDH1,COX6C,ETFA,NDUFB8,SLC25A51,COX7A1,PPP1R2 |
| 8.730e-06 | -11.65 | regulation of T cell proliferation | biological process | GO:0042129 | 181 | 81 | 18204 | 5365 |
IL4,NDFIP1,PRKCQ,GPNMB,TRAF6,IRF1,IL20RB,TNFRSF1B,CTLA4,CD81,DLG1,LILRB4,TNFRSF9,MIR30B,MIR21,PDCD1LG2,AIF1,CCL19,EFNB1,SFTPD,TGFBR2,IL2,CCR2,CD46,PLA2G5,MIR181C,EPO,JAK2,IL15,LGALS3,IL2RA,TNFRSF14,CD80,CD28,IL23A,ARG2,DHPS,LILRB1,IL1B,BCL6,CD274,FOXP3,IL18,PNP,RAC2,PPP3CA,CD1D,SASH3,HMGB1,LEP,CD40LG,AGER,PELI1,TNFSF8,PYCARD,TNFSF18,BTN2A2,IL6ST,PRNP,IL12B,IL10,SLC7A1,XCL1,IL1A,IDO1,SOS2,SDC4,CD209,CCL5,VSIR,IGF1,TWSG1,TFRC,SELENOK,RPS3,NCK1,CD86,IL6,IL21,CTNNB1,GPAM |
| 8.734e-06 | -11.65 | GTF2F2 (general transcription factor IIF subunit 2) | protein interactions | 2963 | 133 | 61 | 19454 | 5460 |
FBXO22,SPCS1,APEX1,TCEAL7,POLR2B,MAD2L1,ZNF330,TNFRSF1B,FAM177A1,CREB1,POLR2F,GTF2F1,GTF2F2,GSK3A,UBE2H,ATF4,ZMYND19,MYC,AR,ANAPC15,FBXW7,PSENEN,PML,FOS,RPA3,TCEA1,RPA2,LMNA,SUMO1,SHMT1,RPL27A,ATG16L1,CFTR,SUPT4H1,TRAM2,GTF2B,CEBPG,SHLD1,MED29,DDX23,BRD3,WWP2,HMGA1,GTF2E1,XPO1,ASF1A,H3C1,KRAS,PAEP,RPL31,EWSR1,TAF10,OTX2,POLR2C,POLR2G,SUPT5H,GTF2E2,CBLN4,MSX2,JUN,LBH |
| 8.832e-06 | -11.64 | RNA polymerase II transcription regulator complex | cellular component | GO:0090575 | 245 | 103 | 19108 | 5553 |
IRF9,TADA3,BATF,STAT2,GTF2E2,BACH1,MAFG,MED17,ADNP,PAAF1,HNRNPAB,GTF2E1,XBP1,HMGA1,HLF,RXRG,MED21,TCEA1,ING2,TAF5L,ATF3,JUN,TAF11,CBX3,SMAD9,MYC,NFIL3,E2F4,MNAT1,CREB1,CCNH,RFXANK,STAT1,FOS,MED11,CTNNB1,CEBPE,CBFB,PPARG,STAT6,VDR,TRIP4,MED31,MED10,STAT5A,RUNX1,TFDP2,SUPT3H,RFX5,MED27,ATF4,CEBPG,DR1,GTF2F1,DRAP1,DDIT3,GTF2H4,RFXAP,CREBZF,GTF2H2,NR1H2,MED23,TAF7,S100A10,JUNB,CDK7,MAX,SMAD5,RB1,NFE2L2,SMAD3,LDB1,BCL9,MED22,SMAD1,GTF2A1,HYAL2,TAF10,E2F6,CREB3,LMO4,ENY2,GTF2B,TAF9,NFYA,MED9,SMAD2,TLE1,MXI1,ATF1,MED30,ERCC3,TAF2,GTF2A2,GTF2F2,GTF2H5,NONO,NFE2,NFYB,SMAD4,MED29,FOSL2,MED4 |
| 8.839e-06 | -11.64 | regulation of intracellular protein transport | biological process | GO:0033157 | 146 | 68 | 18204 | 5365 |
LEP,PKIA,TM9SF4,PRR5L,OAZ2,PTPN11,HSP90AA1,CDK1,IL1B,DMAP1,CDK5,ANGPT1,PTPN1,UHMK1,CTDSPL2,DERL2,UBE2G2,PDCD5,ERLEC1,OAZ1,CDC42,TXN,EFCAB7,OAZ3,HYAL2,RAB29,IFNG,TMEM30A,UBAC2,SIRT7,CHP1,XPO1,SMAD3,ADIPOQ,MDM2,PDCD10,SVIP,EP300,RAB23,CAMK1,PSEN1,CD81,UFM1,EDEM2,SFN,SUFU,ANP32B,BAG3,JUP,HDAC3,PIK3R2,RBM22,PIK3R1,RAN,PKIG,LCP1,SUMO1,CD36,OS9,CHCHD4,SAR1B,MAVS,JAK2,EDEM1,HCLS1,IFI27,VAMP2,CHRM1 |
| 8.839e-06 | -11.64 | innate immune response-activating signaling pathway | biological process | GO:0002758 | 146 | 68 | 18204 | 5365 |
TLR4,PYCARD,CREBBP,RNF34,TLR6,IRF3,PHB2,OTULIN,CD274,SRC,HSPD1,BCL10,MBL2,NLRP1,SYK,LY96,PHB1,PIK3AP1,CLEC7A,KLRC2,TNFAIP3,FCN2,CLPB,TLR3,TNF,EP300,NFKBIA,TMEM126A,MAPKAPK3,KLRD1,TBK1,TIFA,TLR5,PAK2,TLR8,LILRA2,BECN1,IRAK4,TLR10,TICAM2,MYD88,TRAF6,NLRP3,CD14,TLR2,IFIH1,TLR9,TRAF3IP3,OAS1,CGAS,ATAT1,KCNJ8,PRKCE,LACC1,NMI,TIRAP,MAVS,IKBKB,CLEC6A,LSM14A,NLRP6,RIGI,TICAM1,IRF7,TYROBP,TLR7,MAP2K6,TLR1 |
| 8.848e-06 | -11.64 | DNAJC11 (DnaJ heat shock protein family (Hsp40) member C11) | protein interactions | 55735 | 215 | 90 | 19454 | 5460 |
SAMM50,RPA2,COX6C,UQCRC1,TPT1,TUSC2,GRPEL1,TOMM20,SLC25A51,PML,MME,RPA3,RIC3,PPTC7,SAYSD1,SYP,EMILIN1,MGST3,PNP,PITPNB,CYBC1,SYNGR1,STUB1,PDE6D,APOO,MTCH2,FKBP8,PTGES3,SFXN1,DNAJC7,ELOC,ATP1B1,SLC25A46,CD99L2,PLGRKT,TMPO,SPPL3,COX4I1,ARMC1,AIFM1,ANXA7,PIH1D1,LXN,STXBP1,TIMM29,MTX2,TOMM22,TMEM231,UNC45A,FTL,YTHDF1,PHB2,UFL1,AKAP1,HADHA,HSPA8,EXD2,BMPR1A,RIT1,HTRA2,PFDN6,FIS1,CAPG,CUL3,HNRNPC,AUH,MAD2L2,CHCHD3,PPP5C,APLNR,TAX1BP1,SYNE4,VDAC2,LMBR1L,HS2ST1,KRAS,BAG2,RPAP3,HSPB1,HAX1,FKBP4,CTNNB1,XPO1,MARCHF5,FAM174A,UBXN6,COX14,NDUFS8,EGLN3,PHB1 |
| 8.859e-06 | -11.63 | WDCP (WD repeat and coiled coil containing) | protein interactions | 80304 | 98 | 48 | 19454 | 5460 |
KDM1A,RPA3,HSPA8,GHRL,RPA2,CTBP1,MED31,INSYN2A,AGO1,RPGRIP1L,TAB1,CCNF,PHF21A,COP1,YPEL5,UBE2H,EMILIN1,CUL3,CEP85,CIAO1,RUNX1,TIA1,DYNC1I1,RUVBL1,GNL1,ZYX,GARRE1,PICK1,RUVBL2,UBE3A,SPATA6,VPS33A,RHOBTB1,CSNK1E,CD14,KIF2A,MIF,EGLN3,ITK,ETV6,RAB35,ARHGAP25,TRAK2,KRT8,DDX1,CNOT2,XPO1,INSYN1 |
| 8.859e-06 | -11.63 | FLCN (folliculin) | protein interactions | 201163 | 98 | 48 | 19454 | 5460 |
RAB35,LDLR,CCT7,EGLN3,RAB5C,RAB32,FEM1B,YWHAH,AHSA1,CCT8,RAB1A,HSPD1,LDLRAD4,RAB13,TSPAN17,RAB3B,SEMA4C,RRAGB,ZNF609,PTGES3,RAB18,VTA1,TOP3B,FBP1,MAP1LC3B,TUBA1B,DPEP1,STUB1,RAB14,RPL10,PPP5C,CUL3,RAB2A,BAG3,PIP4K2C,FBXW11,CCT2,LAMTOR1,HSP90AA1,RAB29,RAB9A,RAB33B,SF3B1,GABARAP,WDR77,RRAGA,RABL3,AGAP1 |
| 8.874e-06 | -11.63 | CTTN (cortactin) | protein interactions | 2017 | 400 | 152 | 19454 | 5460 |
HSPA5,AIF1L,HMGB1,ARPC2,RNF113A,BAP1,UGDH,RPA3,PML,UBE2M,MET,HEXIM1,TOX4,RPA2,LMNA,CD2AP,SPTBN1,SUMO1,ARHGAP1,SMURF1,PPP1R10,CTTNBP2NL,IDE,SH3BGRL,SUCLG2,SRC,DAPK1,NDN,YES1,PSPC1,CCNF,METAP2,CTTN,CTNNA1,CA2,NCKIPSD,MAPRE1,UBE2H,MECP2,TXNIP,BICD2,CFL1,CFL2,NONO,RSPH1,AKT1,VTA1,CTNND1,MEPCE,CAPZA1,CAMK2G,WASL,RPL23A,PPP1R12A,FAF1,SNIP1,APEH,TAF2,NUPR1,DDX42,CAPZA2,ARPC3,ACTR2,MAP2K3,EEF1A1,KBTBD4,RRM1,UBL4A,RPSA,CDK9,NOP9,TOP1,PRNP,PREP,TES,SYNCRIP,SHC1,COPS5,TMA16,HDAC6,PPIL4,YTHDF1,OXCT1,STAU1,GPC1,HSPA8,STK26,EP300,HIRA,SPECC1L,NUFIP2,MFAP1,PIH1D1,PPP1CB,ATP6V1C1,NDE1,SYK,EFHD1,SHMT1,APEX1,STAT1,MATR3,ACTB,FBXO22,SF3B4,TACO1,KCNA3,VMP1,RCL1,MYO6,H1-10,RBM15B,MYC,COPS7A,RAB11A,CUL3,RPS27A,RAD21,CBLL1,ASF1A,EWSR1,FAM76B,MYO1B,PDIA6,CTTNBP2,SART3,PDHA1,CHMP4C,ACTN4,SOX2,TULP3,CSNK1E,EGLN3,HNRNPL,FAM98A,LYAR,SNX2,TRIM15,SNX1,SPTAN1,CORO1C,WDR82,THY1,SDHAF2,RPL9,DNM2,KCNA2,HAX1,CBL,ATG7,NDC80,WWP2 |
| 8.968e-06 | -11.62 | MRPL57 (mitochondrial ribosomal protein L57) | protein interactions | 78988 | 106 | 51 | 19454 | 5460 |
AGR2,RHOG,MRPL18,SKIC8,HNRNPA1,CIDEB,MALSU1,MRPL50,GATD3,FAHD1,PRR3,MRPL51,SKA3,DDX39A,MRPL47,RPL17,MRPS11,RPL23A,EWSR1,MRPL52,RIT1,UBE2H,FBXW11,TAFAZZIN,PSMD1,RPL7A,MYC,FMC1,CREB3,RPL19,RPL10,PSMD6,RPL13A,MRPL23,PSMD4,MRPL13,MRPL53,MTRES1,ZNF574,MRPS18A,MRPL12,RBMS2,PLP2,MRPL10,FTL,ABCC2,PSMC1,MRPL41,GFM1,PGK1,NGRN |
| 8.968e-06 | -11.62 | PDRG1 (p53 and DNA damage regulated 1) | protein interactions | 81572 | 106 | 51 | 19454 | 5460 |
CAMLG,POLR2L,RPRD1A,POLR2I,WWP2,DCAF4L2,MED21,DCAF5,SKIC8,MED4,HNRNPD,ASB7,RPAP3,RUVBL2,DNAAF10,RUVBL1,KRAS,PTGES3,PDRG1,PFDN1,E2F4,KBTBD4,TUBA1A,RPAP2,POLR2D,POLR2C,POLR2G,POLR3H,POLR2F,POLR3B,MAP3K3,RANBP6,RPL10,POLR2B,PPP1CC,RNF40,BTF3,PFDN6,POLR1B,PFDN4,HSP90AA1,PFDN2,FBXW4,BAP1,POLR1H,TRIM52,POLR1D,PPP1CB,RPRD1B,PIH1D1,PARD6A |
| 9.022e-06 | -11.62 | RNF31 (ring finger protein 31) | protein interactions | 55072 | 394 | 150 | 19454 | 5460 |
PRSS1,HSP90AA1,CHTOP,RPS29,MLF2,CPSF2,RPL39,CUL3,LMO2,MYC,ERH,RPL35,ACTB,TAB1,STAT1,PACRG,EIF4B,OTULINL,WDR77,UBE2D3,TRA2B,PSMA3,BIRC2,HSPA8,SPATA2L,XRCC5,CD40,RPL23,TRAF6,PPM1B,UBE2D1,STK4,TRA2A,BTF3L4,SPATA2,IQSEC1,HNRNPA1,YWHAG,UBE2E2,UBXN6,HSP90AB1,SRSF10,TCP1,MPP1,HNRNPL,RPS10,TRIM35,KRT8,SRSF1,RPS23,OTULIN,EIF1AX,TUBB4B,TRAF2,CARTPT,FAF2,RPL29,PPIL3,PRPS1,SRSF4,GTF3C3,VDAC1,HNRNPF,TNF,BAG2,SRSF7,LDLRAD4,PABPC1,CCT8,HNRNPA2B1,HSPD1,SLC25A5,CALU,IGF2BP1,NR0B1,UBE2E3,IVNS1ABP,AR,RPS17,RPL26,SLC25A1,TNFAIP3,TRAF1,UBE2L3,UBB,ADRM1,MAGOHB,TXN,PTEN,RPS20,INTS12,RPS12,CALML5,TNFRSF1B,CCNF,OPTN,RPS3,FKBPL,HNRNPH3,PRKCA,CHMP1A,EIF3J,UBE2W,PSMC4,RPS14,HSPA5,STK38,UBE2K,IRF7,GPX4,SQSTM1,H2BC12,MAVS,PRKCB,PRIM2,RPL27,MAIP1,AKAP8L,BCL10,HDAC6,HM13,ZNF24,RPS27L,RPS16,EEF1AKMT3,ALYREF,SMAD3,TAB2,TLR3,METTL15,RPL15,SOCS3,EEF1A1,AZI2,TP53,CCT5,UBL4A,TBK1,PREB,RIGI,VRK1,RBCK1,THRAP3,TSSC4,TRAFD1,SLC16A1,RPL23A,LTBR,SLC25A10,MAP1B |
| 9.119e-06 | -11.61 | IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial) | protein interactions | 55699 | 256 | 104 | 19454 | 5460 |
MGST3,CCNF,STK11,CALU,DNAJC19,CHORDC1,TUFM,TOMM20,GRPEL1,CRYZ,FBXW7,HNRNPH2,DERL1,GFM1,SQSTM1,RPA3,SIRT7,HNRNPH3,MTRES1,JUP,RPA2,MALSU1,PLGRKT,ARF6,HSD17B11,AIFM1,SSBP1,ARL10,COX4I1,DNAJC7,SMG8,DNAJC4,CHCHD1,TMEM70,GRSF1,FASTKD5,DNAJC30,CLPB,SFXN1,GFM2,ILF2,AURKAIP1,METTL15,MRPL11,TP53,PARL,MATR3,STAT2,SMU1,IRF2,TACO1,CCDC90B,MTG1,PFDN4,HSP90AA1,HTRA2,RIT1,LAMTOR1,MTG2,AUH,PMPCA,CUL3,NT5C3A,HSCB,UFL1,PHB2,RER1,AKAP1,NGRN,SNRPA,EXD2,FOXS1,ASB8,COX14,RMND1,HSP90AB1,YBEY,GJA1,GATD3,MRPS26,PEX3,HSPB1,RHOG,AGR2,DRG2,YWHAG,ATG7,YWHAH,MTRF1,PFDN5,IMMP2L,FLOT1,KRAS,EPHA4,HINT2,COX8A,HSPD1,RNF126,EZH2,PDHA1,CHMP4C,PTRH2,ASPM,RAF1 |
| 9.119e-06 | -11.61 | COA3 (cytochrome c oxidase assembly factor 3) | protein interactions | 28958 | 85 | 43 | 19454 | 5460 |
LMBR1L,UQCRC2,VDAC2,UQCRQ,MAD2L2,ATP5F1B,MGST3,TOMM40,PCCB,TUFM,NDUFB10,CMC1,TAFAZZIN,HADHA,RPA3,PDHB,NDUFS2,PHB2,UQCRC1,CYC1,ATP5PO,VAPB,RPA2,CYB5A,ATP6V1A,PHB1,COX4I1,NDUFS8,ATP5PD,COX14,COPS5,MOV10,COX5A,NDUFB8,TMEM70,NDUFA4,CTNNBL1,COX4I2,ATP5PB,MTCH2,SLC25A24,PDHA1,NDUFS3 |
| 9.168e-06 | -11.60 | TADA2A (transcriptional adaptor 2A) | protein interactions | 6871 | 195 | 83 | 19454 | 5460 |
GPSM3,FANCG,CDCA7L,SRSF4,KPNA2,DHX16,HNRNPF,CDC40,WDR37,HELT,IKZF5,ELF1,CCDC134,TP53,PSMC3,HGS,TAF10,ILF2,POLR2C,NFE2L2,CDK8,KRT8,MYEF2,SRSF1,EIF4E2,SIN3A,CDC5L,DHX15,THOC1,TTC9C,TRA2A,CTNNB1,PRPF19,ZNF688,MAGOH,MED4,TAF9,MED29,MED27,DDX5,DR1,SNRPA,RNF41,HSPA5,OGDHL,TRA2B,KDM1A,SGF29,KLF12,SUPT3H,MED30,MTX2,CSNK1G3,LUC7L3,MED31,MFAP1,SUPT7L,MED23,KLF3,PPARG,PHF21A,MCPH1,PSPC1,UBB,POLR2B,MAD2L1,MED17,MAGOHB,TTC23,NONO,PCBD1,PRPF31,ZCCHC12,MED22,HNRNPC,TAF5L,MYC,TADA1,FAM107A,CCHCR1,EXOC8,HSP90AA1,TADA3 |
| 9.168e-06 | -11.60 | BECN1 (beclin 1) | protein interactions | 8678 | 195 | 83 | 19454 | 5460 |
PIK3CG,TRIM21,TCOF1,TOP2B,CAMK2G,DYNC1I1,JUN,TRAF2,MAP2K3,TP53,CDK4,RAF1,NLRP2,BIRC5,TAB2,JOSD1,CDK6,S100A8,GJA1,MCL1,MAP2K6,DIRAS3,GRM1,HYPK,FZR1,NGDN,YWHAH,ATG7,XPO1,YWHAG,EDEM1,USP15,BCL2L1,YWHAB,STYK1,HAX1,LSM3,RB1CC1,KDM2A,PSMD10,TRAF6,EXOC2,BECN1,SQSTM1,TERT,BIRC2,PGK1,MAPKAPK3,TRIM3,HSPA5,NRBF2,FBXW7,HMGB1,STK38,NF2,SGF29,NEK2,KDELR2,HSPB6,NLRP6,BAD,ESR2,DYNLL1,YES1,DAPK1,TUFM,USP14,AR,OTUD7B,ATG101,PYCARD,CUL3,AKT1,TNFAIP3,TRIB1,NLRP3,EPHA2,SMAD2,HSP90AA1,STK11,EXOC8,BRCA1,ATG3 |
| 9.204e-06 | -11.60 | TRIM37 (tripartite motif containing 37) | protein interactions | 4591 | 624 | 224 | 19454 | 5460 |
NTNG2,FAU,ZMAT2,CDC7,TUBB,RPL35,ACTB,EIF4A2,RPL19,GNB1,CUL3,HNF1B,YWHAZ,MYO6,HSP90AA1,FAM107A,RPS5,PYGB,NOTCH2,H1-5,PPARG,MED23,MYL6,SLC25A3,PHB1,RPL8,RPL9,KRT8,CCAR2,RPL7,SPTAN1,RAB11B,PPIA,CNTROB,EGLN3,ERLIN1,PRDX1,HMGA1,PDIA3,HNRNPA1,TRAF6,UBE2D1,RPL23,CAMSAP2,HNRNPD,VCPIP1,HNRNPA2B1,MAEA,HSPD1,SCYL2,SLC25A5,BAG2,PCNA,S100A10,TRIM37,RRAGB,ZNF592,RPS27A,ZNF263,FAF2,KIAA0408,RPL29,ACTN4,NME1,EZH2,RPN1,CYB5B,RPS11,ENO1,TNFRSF1B,TUBA1B,LURAP1,NUDT18,TRIM24,RPS20,PTEN,ALB,RPS12,TRIM27,RPL13A,TMOD3,LDHA,VIRMA,RPL22,UBB,CDC16,PPP1CC,TUFM,ATP5F1A,RPL26,MYH2,SQSTM1,ARPC2,RPL4,B2M,FAM161A,ATG16L1,RPS14,FTH1,SIPA1L1,HSP90B1,LMNA,RPLP0,KRT7,RPL12,HACD3,LDLR,RPL35A,CAV1,G6PD,SSX2IP,RAB1A,LTBR,RPL23A,ZC3H11A,MT1E,CAMK2G,HUWE1,ARF4,RPS13,EEF1A1,ACTR2,SCNM1,MOG,APEX2,VDAC2,ATP5F1B,ESR2,RPL10,HNRNPC,PCCB,RBM27,S100A11,RPS26,RPS28,FAM50B,XRCC5,DDX39B,HSPA8,EEF1G,STAU1,PHB2,UBE2D3,FXR2,MT2A,TANK,EFHD1,CD59,BORCS6,CAV2,DUSP6,CORO1C,RFX5,TCP1,HSP90AB1,RPL6,UBE2E2,DIRAS2,CTNNB1,SPATA2,PPIB,XPO1,HSPB1,RPL31,MYO1B,TRIM21,EWSR1,VDAC1,RPL28,PI15,EEF2,RPS7,TRAF2,TUBA1A,TUBB4B,CSTPP1,RPL18,APTX,UBN1,RPS3,ZNF655,MACROH2A1,RPGRIP1L,IRF2BP1,TRAF1,SMURF1,PPP1R10,RPL7A,CCNB1,CEP85,SUB1,CFL1,UBE2E3,UBE2H,RPL27,UGDH,DLAT,RASD1,HSPA5,SPTBN1,CDC42,H2BC11,ALYREF,SSBP1,SYNCRIP,DSTN,RAP1B,RPS16,SLAIN2,MYL12A,PGAM1,EDC3,TPM3,GAPDH,RPL24,H2AC4,RPL10A,MAP4,DHX9,RPL3,CAPZA1,TP53,ARPC3,DISC1 |
| 9.215e-06 | -11.59 | KRT9 (keratin 9) | protein interactions | 3857 | 147 | 66 | 19454 | 5460 |
SAR1B,ARF4,MEPCE,TRIM37,TNF,ARL5B,NEDD8,UBE3A,FAF1,RNF8,EZH2,LGR4,ISG15,TP53,FBP1,TBK1,DYNC1I2,DCUN1D1,CAND1,ARL4D,ARL10,PHB1,EFNA3,MAGOH,CBL,POU5F1,AGR2,SHC1,PPM1B,TRAF6,DDRGK1,COPS5,HNRNPA1,HDAC6,EMC4,DIRAS2,DPP4,FBXL4,ADRB2,PIK3R2,UFL1,NMRAL1,WBP2,BAP1,DDX39B,INPPL1,WTAP,PIH1D1,HEXIM1,METTL14,CFTR,VIRMA,NDN,KCTD9,UBASH3B,ALB,AP2M1,EIF4A3,RNF208,UBE2H,TRIM23,RC3H2,BTF3,CUL2,CUL3,MYC |
| 9.215e-06 | -11.59 | SIRT2 (sirtuin 2) | protein interactions | 22933 | 147 | 66 | 19454 | 5460 |
PHB2,GSTT2B,FBXL4,RPA3,RTN4,DERL1,SQSTM1,EP300,MTDH,HSPA8,SYVN1,MAP2K1,NUDT12,RPA2,SCLT1,BORCS6,OTULINL,PPP1CB,MANSC1,RPGRIP1L,CDC20,RAN,CTNNA1,VDAC2,ANAPC2,RMDN3,SNRPD1,LAMTOR1,SPOP,OXTR,DNAJB6,PAPOLA,AKT1,BAG3,TUFM,H3C1,GSTT1,IMMP2L,SLC25A5,MORC2,HSPD1,SRSF7,ACTR2,RP9,STIM1,MTCH2,TBK1,TOP3B,GPAM,ING1,DYNC1I2,RPL7,FZR1,VAMP7,MDM2,ACTA2,GYS1,KRT8,MCL1,HSD17B11,H2AC4,DEGS1,AHSA1,CBL,XPO1,HDAC6 |
| 9.256e-06 | -11.59 | POLD1 (DNA polymerase delta 1, catalytic subunit) | protein interactions | 5424 | 221 | 92 | 19454 | 5460 |
MGMT,YWHAB,HSPB1,ATG7,XPO1,HSPB8,CNOT2,UBXN6,EGLN3,LRRC61,WDR44,GFOD1,TCP1,SUMO2,ARHGAP25,PHB1,RNF126,RPN1,RAF1,COPS4,KRAS,LASP1,PCNA,RUVBL2,RTCB,BAG2,S100B,CCT8,COP1,POLD4,RIT1,BRCA1,MCM3,MYC,CUL3,SFN,APEX1,ESR2,MATR3,SNRNP40,FBXO22,TUBB,MCPH1,CRYBB3,MFAP1,MED23,RFXANK,POLA2,CCND3,HSCB,UFL1,SLC31A1,STAU1,HSPA8,DDX5,XRCC5,DNAJC7,COPS5,PTP4A3,POLE3,CDC5L,TOP1,RB1,EEF1AKMT3,TAF2,TBC1D4,GINS4,CCT5,CDK4,TP53,MDC1,CTNNBL1,RBCK1,FARSA,DHX9,ATP1A1,UBE2H,AR,CIAO1,CCNB1,CCNF,CIB2,RPA2,CDK1,CCNA2,ATG16L1,PRKCB,DVL2,BAP1,PRIM2,RPA3,POLD2 |
| 9.265e-06 | -11.59 | immune response | biological process | GO:0006955 | 1349 | 468 | 18204 | 5365 |
TLR1,IL15,TICAM1,BMPR1A,SIT1,IL23A,LILRA1,TFE3,SEMA7A,LYZ,SAMHD1,EXOSC3,PIK3R1,TRIM10,PIK3R2,CTNNBL1,IRF1,PQBP1,OSM,CCL1,IFI16,OPRK1,TLR8,BPIFB1,ACTR2,NBN,IL17F,CD47,ICAM1,FAU,SERINC3,IFNG,TCIM,PRKRA,CAMP,TMEM45B,LGR4,PNMA1,PRDX1,TNFSF12,EXT1,IL18,SRC,TRIM35,PHB2,HEXIM1,CNIH1,FGL2,CD58,REG1B,PIK3CG,TFEB,CD1A,TRIM21,CD40LG,FASLG,RNASE4,TASL,IL2RA,SEMG2,PSPC1,CCL2,PML,TUBB,ARG2,RNASET2,KCNJ8,NFKB1,CCL4L1,APOBEC3A,SNAP23,TRAF6,TLR2,RARRES2,CD1B,TLR10,TICAM2,SFTPD,CCL19,VAMP3,TLR5,XRCC5,TBK1,CTLA4,CD2,IFIT2,SARM1,SMAD3,DEFB115,KLRC2,TRIM32,PDCD1,TRIM62,LAMP3,YES1,CH25H,SYK,CLU,CCR4,NLRP1,CD40,OTULIN,CCL23,S100A8,FCGR2B,APOBEC3C,TRIM5,GPR65,MAD2L2,LYAR,IFI27,SIN3A,RIGI,CLEC6A,SERPINB9,NMI,POLR3F,OPTN,CDC42EP4,CD80,GNL1,TNFRSF1B,TLR9,IFNK,EMP2,WFDC5,LEAP2,SYNCRIP,SH2D1A,JAK1,RGCC,LST1,DHX16,LILRA2,AQP4,LCP2,IFNA2,CXCL3,CXCL9,FOXP1,G3BP2,POLR3B,FGR,ALCAM,RNASE6,MX2,DDX1,FCER1G,TREML1,IL12B,TRAF3IP2,PI3,RSAD2,CSK,IL6,IFNA10,PYDC2,CD86,CD79B,VPS26B,TRIM34,PNP,FOXP3,CD274,HSPD1,MX1,TMED1,MATR3,IFNGR1,CXCL14,DAPK3,RPL39,STXBP1,JAK2,STAT1,IRAK1BP1,BST2,CCL28,TIRAP,LACC1,PRKCE,CPLX2,DEFB114,LCP1,RAB27A,CDC42EP2,XBP1,RPL13A,TNFSF13,TOLLIP,EIF2AK2,FAS,CD14,TUBB4B,KIT,IL2,MIRLET7B,MSH6,FCAR,UBE2N,KLRD1,LAT2,ROMO1,UBE2W,FBXO9,PIK3R3,CD164,KARS1,SP2,SHLD1,CTSK,TMEM106A,CCL24,CXCL11,TNFSF15,IL1B,IFNA13,NCR3,TLR6,TANK,SLAMF9,SEMA3C,ISG20,LGALS3,PTGDS,IKBKB,IL34,GAPDH,CYP27B1,TRIM15,SDHAF4,GAPT,YTHDF2,B2M,ITK,IL7,IL3,NQO1,CD3G,TNFAIP8L2,SLA2,IRAK4,CXCL13,FCMR,SLC15A2,PPARG,PTGER4,CD247,APOBEC3H,RGS1,CXCL8,TNFSF10,CD1E,CTSC,SPAG11B,ST6GAL1,TP53,MADCAM1,CLEC7A,IL21,AZI2,ENDOD1,H2BC12,IL13,ACKR3,TMEM33,LILRA3,CCL11,MICB,CCL8,DCLRE1C,AZGP1,NONO,SEC14L1,TRIM27,IFI6,TLR4,TNFRSF14,VAMP2,CXCL10,ICOS,APOBEC3B,CCL18,CASP4,RAG1,CYP11B1,CGAS,TNFAIP1,NLRP2,CITED1,TRIM23,CXCR3,CCL25,NLRP3,CD1C,CEBPG,CCR2,F2,IRF4,TIFA,AIF1,PDCD1LG2,DEFB121,CCR3,TNF,RAF1,CX3CL1,RBPJ,XCL1,IL10,FCGR2A,NMBR,TRAF2,CX3CR1,MRGPRX2,VAMP7,PDIA3,PDE12,LY96,TRIM6,PHB1,HMGB1,CD1D,MBL2,CXCL12,BCL6,CXCR1,ITGB8,CXCR4,GTPBP1,PYCARD,HRAS,IL1RAP,BATF,NCR3LG1,CHID1,TRIM11,IFNB1,MCOLN1,TYROBP,SOCS3,MAVS,CCL27,RC3H2,ZYX,SWAP70,CD28,TAX1BP1,MEF2C,MSRB1,ST3GAL1,POLR3H,IFIH1,IL20RB,PSMB10,SLPI,MYD88,IL4,APOBEC3F,CD46,CLDN1,PDP2,PLPP6,TRIM26,NLRP9,CD4,LILRB4,CD81,PSEN1,MIR146A,CCL5,CNPY3,G3BP1,ITM2A,IL2RB,DEFB124,TRIM68,TLR3,CCL17,IGF1R,IFNAR1,DAPK1,CDC42,APOBEC3G,FTH1,CCL3,CD83,BPIFB3,APOBEC3D,MIF,IL12A,BCL10,LILRB1,APLN,PELI3,CSF2,NFIL3,STX8,IRF3,AKAP1,TNFSF8,IL5,USP14,IRF7,TLR7,NLRP6,H2BC11,TRIM29,DHX15,MAP3K14,LTA,FOSL2,IRF8,CHGA,MRC1,PRKCB,CCR1,REG1A,FCGR1A,OAS1,CRHR1,CCDC92,TRIM22,IL1R2,CCL21,CYBC1,CCR5,FAM3A,S1PR4,CBL,STAT2,IFI35,ATP1B1,LTBR,CRIP1,NOTCH2,SRPK2,CD209,CLPB,FCN2,IL1A,HRH2,LTB,DEFB1,DEFB116,TF,TRIM8,IL18BP,NCK1,OTUD7B,IL2RG,CXCR6,DHX9,VAMP8,C1QC,TTC4,UAP1,CCR6,CCR7,ISG15,RNF8,STAT6,TNFSF18,WFDC13,CXCL1,JCHAIN,CCL20,HCFC2 |
| 9.288e-06 | -11.59 | Ntn_hydrolases_N | interpro domains | IPR029055 | 33 | 22 | 18521 | 5414 |
PSMB6,PSMA1,PSMA2,PSMB9,PSMB7,PSMB1,PSMB11,PSMB2,PSMA5,PSMA6,PSMB3,PSMB5,PSMA3,PSMB4,AGA,PSMA4,PSMB10,GFPT1,PPAT,GGT7,ASRGL1,ASNSD1 |
| 9.291e-06 | -11.59 | VDR (vitamin D receptor) | protein interactions | 7421 | 125 | 58 | 19454 | 5460 |
MED21,MED4,FGR,NFKB1,RNF14,TAF7,HR,CSNK2A1,SNX18,MDM2,SMAD3,GTF2B,RXRG,RB1,COPS2,GNPAT,EZH2,ACVR1,UCKL1,VDR,TP53,GABARAPL1,JUN,ACTN4,ZBTB16,THRAP3,CDCA7L,BRCA1,CXXC5,POU1F1,SP1,NLRP3,CNRIP1,CREBBP,MYC,CUL3,NTAQ1,RUNX1,PPP1CC,STAT1,NR1H2,TAF11,SRC,PSMC5,TRIM24,MXD1,PPARG,MED23,GABARAPL2,CDK7,CDKN1A,PRCP,ATP6V1G2,STK38,CCND3,FOS,EP300,SQSTM1 |
| 9.291e-06 | -11.59 | BCL2L14 (BCL2 like 14) | protein interactions | 79370 | 125 | 58 | 19454 | 5460 |
IDH3B,PCK2,DDIT4L,COQ8B,RABL3,CDK1,ACAA2,EIF2B3,MAIP1,NDUFS2,BOLA2B,OXCT1,TUFM,PYCR2,BAX,CALU,SDF2L1,TRAPPC14,PSMD14,PRMT5,BAD,POLR2B,SUCLG2,USP5,NDUFAF4,COPE,RBBP4,LGALS3,TUBA1A,PPP2R1A,TP53,MLLT11,MTA2,NUDT19,PICK1,HSD17B10,TRAPPC1,MAP1B,FASTKD5,FKBP8,RBBP7,YWHAG,COPS5,TRAPPC4,BCL2L1,TUBG1,TRAPPC2L,TRAPPC3,TRAPPC10,GATD3,COQ8A,AIFM1,RPRD1A,SDHB,HDHD5,TRAPPC6B,TOMM70,PRNP |
| 9.292e-06 | -11.59 | response to hormone | biological process | GO:0009725 | 784 | 286 | 18204 | 5365 |
SLC22A12,CYP11B1,TYMS,RB1,CITED1,GPR83,RAB31,KCNJ8,NFKB1,CYC1,WBP2,CDKN1A,VAMP2,INPPL1,FOS,HCLS1,CSNK2B,ACAT1,STAT5A,VPS54,FOXC2,CCL19,TLR2,RARRES2,FKBP4,CYP1B1,CD2AP,NEFL,CD38,PHB1,CRHBP,AVPR1B,UBE2L3,MIR145,PAQR8,ATP1A1,SMAD3,RAF1,PTGFR,ROCK2,IL10,CYP11B2,STC1,RBBP7,LHB,SLC2A1,TNF,ADIPOQ,HRAS,STK11,ADIPOR1,NKX3-1,HDAC6,FBP1,CAB39,CLDN4,CXCL12,GNB1,MME,EIF2B2,TIMP1,SRSF4,ESR2,FGF23,EGR1,CYP27B1,TRIM44,ALPL,MKKS,AKR1C2,NR4A2,ABHD2,AKR1C1,NFE2L2,EPO,PTGDS,SHOC2,PTGER4,CCNA2,MIR493,RXFP2,EIF2B5,SFRP4,SP1,OPRK1,PPARG,SESN2,PGR,RAN,BTG2,TSPO,PIK3R1,GAB1,NR2E1,NQO1,CDO1,PIK3R2,CDKN1B,DDX5,LEPR,POR,MIR143,PDCD4,ROCK1,GPR173,SOST,HADHA,F7,TNFSF10,PIK3CA,TAF7,MDM2,REG1B,LEP,INSIG2,TOMM70,FIBIN,ZBED3,PHB2,TFPI,PTPN11,GHR,ADRA1A,SRC,DAG1,PTPN1,HSPA8,GNG2,TSHR,MGARP,PTGES3,COMT,CSH1,TRIP4,SST,UGT1A1,TIMP4,REG1A,UGCG,CRHR1,ACACA,IDH1,TWIST2,RAMP3,FOSL2,SHC1,GSK3A,CRY1,EGLN2,PRKCE,HDAC5,STAT1,NR1H2,CAV2,GAD2,LRP6,CTSB,PCSK9,OR51E2,EIF4EBP2,LCN8,JAK2,AR,TRIM24,ATP1A2,RAB13,NCOA5,CCND1,TRIM63,CTNNA1,PID1,IL22,STAT2,XBP1,RPL27,CPEB1,TADA3,GHRL,CCL21,GRIA1,EIF2B3,GPT,MT3,GPX1,RETN,OXTR,GJB2,SESN3,GH1,CTSK,AANAT,PCNA,NPR2,MAP1B,AGTRAP,PIK3R3,TGFB2,CALR,EP300,UCP2,ADTRP,CST11,SELENOS,FKRP,GRB10,ITGA2,CCR7,STAT6,DDIT4,AKT1,AIFM1,TBC1D4,TGFB3,SPP1,GCLC,KBTBD2,P2RY4,COL3A1,FAM107A,WNT7A,MEF2C,RERG,MSTN,EFNA5,UCN,RBFOX2,SERPINB9,EDNRA,TXNIP,USP8,WNT10B,SMYD3,CAV1,PAX6,DTYMK,HADH,EGR2,GPR22,ATP1A3,IDE,CLDN1,TACR1,JAK1,PLCB1,PCK2,GNRHR2,RWDD1,MIR107,BGLAP,PADI2,SOCS2,ADIPOR2,EIF4E,FBXO32,MIR379,TIMP3,PTGER2,SFRP1,IGF1R,CSK,AHCYL1,CREB1,IL6,SOS2,PELP1,UBE3A,RNF14,MMP14,GNRH1,SLC2A8,GSTM3,ACVR1C,YWHAG,UPRT,RXRG,PPARA,HSP90AA1,REN,INPP5K,CA2,KLF9,ERRFI1,YWHAH,PRL,AKT2,ATP5F1A |
| 9.319e-06 | -11.58 | PRPF4 (pre-mRNA splicing tri-snRNP complex factor PRPF4) | protein interactions | 9128 | 262 | 106 | 19454 | 5460 |
SRPK2,TMOD3,ADRM1,CCNF,UBE2H,SPOP,LSM6,RC3H2,SMARCA5,HSPA5,LSM8,DGCR8,FBXW7,CLK1,RTN4,PPIH,PML,PRPF4,TFIP11,HEXIM1,RPL26L1,AGAP1,WRAP53,LSM2,SNRNP27,TXNL4A,SF3A1,SNRPN,RBM42,FZR1,RPS16,CAND1,TOP1,ALYREF,RPL32,CDK12,LSM3,MAP4,USP15,SNRNP70,NOS1AP,COPS5,OLA1,MEPCE,SNRPG,LSM4,METTL18,SNIP1,CERK,NUPR1,CD2BP2,CCT5,PSMB6,SNRPB2,ESR2,SNRNP40,PRMT5,SNRPD2,FAU,CPSF1,TACO1,PFDN4,PFDN6,RIT1,CCT2,PRPF31,SNRPB,MYC,CUL3,COIL,GPHN,HSPA8,SF3B1,SNRPA,DDX39B,USP39,PSMB7,CCT7,DHX15,RPS10,SNRPA1,SNRPD3,LSM5,TCP1,SRSF1,MGMT,DDX23,XPO1,HNRNPA1,DDRGK1,PSMD3,PRPF19,PFDN5,PFDN1,SSRP1,KRAS,PSMA1,CHCHD2,RUVBL1,RUVBL2,CCT8,SNRPE,SART3,SOX2,CSNK1E,E2F4 |
| 9.319e-06 | -11.58 | ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1) | protein interactions | 25820 | 262 | 106 | 19454 | 5460 |
CAMKV,PDE12,NEDD8,CTSC,RIGI,RAB1A,KLHL15,ILF2,KLHL26,CASK,DCUN1D1,KCTD3,RBM42,DKC1,CAV1,SRP14,EIF4E2,UBE2N,IRF9,H2AC14,KLHL9,TCEANC2,ANKMY2,ELOC,KLHL22,KDM1A,FBXW7,BTBD10,SNAPC1,RPA3,TNFAIP1,P3H1,IPP,ZNF574,CSNK1G3,ZNF501,PIP5K1A,ELP3,KCTD9,UBE2L3,JUNB,CREB1,OPTN,CCNF,SYT2,RCBTB1,SPOP,AP2A1,TNFAIP3,SEC13,DHPS,ZNF687,FBXO7,CFL2,KRAS,FEM1C,FBXO3,KLHL25,FBXO11,TRIM21,SNRPE,SSBP3,KLHL12,ZNF263,PPP2R1A,JUN,TULP3,HNRNPL,SNX18,KCTD10,CBFB,KLHL7,FBXO32,XPO5,UBE2D1,CDKN1B,DDX1,HSPB1,DICER1,VPS26A,UBE2E2,BTF3L4,UBE2D3,GNB4,SKP1,UPF3B,CRY1,APPBP2,DR1,USP39,VAV2,LRRTM3,ZER1,EHHADH,ETF1,FBXO22,RPL10,KBTBD6,FBXW11,BRCA1,RIT1,SETD7,CUL2,CUL3,PRPF31,ATF1 |
| 9.394e-06 | -11.58 | FAM91A1 (family with sequence similarity 91 member A1) | protein interactions | 157769 | 136 | 62 | 19454 | 5460 |
TRIM52,STX7,FBXW7,RAB9A,NUBP2,RAB5A,CXCR4,RPA3,SLC22A8,RPA2,CDC42,KDELR2,RND2,HCST,BET1,TUBB,SYBU,CHRM4,ANAPC4,FIS1,LAMTOR1,FAS,TXNIP,RHOB,RAB2A,NUDT1,RAB11A,CUL3,KRAS,HUWE1,RAB3B,BAG2,TMT1A,AQP3,RAB4A,ZNF397,RAF1,TP53,STX6,LMAN1,DIRAS3,SPPL3,ARF6,RHOH,LHFPL4,RAC2,RAB35,AIFM1,SSR2,EEF1AKMT3,ARL10,MED4,DRG1,RHOG,XPO1,ATG7,TNFAIP6,ATG9A,LAMP2,UBXN6,FAM174A,RAB5C |
| 9.394e-06 | -11.58 | CLCN7 (chloride voltage-gated channel 7) | protein interactions | 1186 | 136 | 62 | 19454 | 5460 |
SEC61B,FAM177A1,ACP2,ATP6AP2,RHOJ,MANSC1,MBLAC2,DNAJC5,CREB3,RAB2A,RAB11A,OPRM1,TMEM179B,LAMTOR1,BLVRA,LGALS8,RHOB,LMNB1,MYO6,MTDH,RAB5A,DERL1,RAB9A,RHOU,TMEM47,STX7,OTULINL,RND2,SEC62,CDC42,ST7,BET1,LMNA,SSR1,SLC66A2,HSD17B11,RAC2,RAB35,LMAN1,STX6,CAV1,TLCD4,ARF6,CGAS,RHOH,LAMP3,DPP4,LAMP2,RAB5C,SLC38A7,RHOG,OSTM1,UBE2A,KRAS,RAB3B,TOP3B,TP53,CTXN1,VAC14,CYB5B,RPN1,RAB4A |
| 9.426e-06 | -11.57 | MRPL49 (mitochondrial ribosomal protein L49) | protein interactions | 740 | 178 | 77 | 19454 | 5460 |
GFM2,STK16,MRPL51,SOX2,DUSP1,METTL15,MRPL47,MRPL11,MEPCE,FASTKD5,RPL17,KRAS,TOLLIP,HINT2,SNIP1,MRPL52,METTL18,MRPS26,MRPL18,RHOG,TMEM70,SNRNP70,CHCHD1,MRPL9,COPS5,GRSF1,MOV10,MTRF1,RPL6,CAND1,MRPL50,GATD3,SSBP1,HRAS,PHB1,ALYREF,MTRES1,MRPS18A,MRPL10,CDC42,RBMS2,GABARAPL2,MRPL12,KLF12,TIMM10,RPL27A,NHP2,HSCB,TMEM177,TRA2B,MRPL17,MRPL41,MIS12,GFM1,NGRN,EXD2,SCFD1,UBE2H,DNAJC19,STK24,FBXW11,RPL26,TUFM,MTG2,MYC,AUH,CUL3,PMPCA,RPL19,MGST3,MRPL23,RPS9,MRPL13,TACO1,MRPL53,MTG1,DLST |
| 9.426e-06 | -11.57 | BRAF (B-Raf proto-oncogene, serine/threonine kinase) | protein interactions | 673 | 178 | 77 | 19454 | 5460 |
SLC25A11,NDUFA4,RAB1A,IGF1R,FARSA,TMEM33,KRAS,MDC1,RPS27A,RAP1A,FBP1,RAF1,MAP2K3,TRAF2,PIK3CA,PPP2CB,MAP2K6,PHB1,HRAS,WDR6,H2AZ1,DELE1,RAP1B,MRAS,CCT7,HSP90AB1,STK3,WWP2,PGAM1,YWHAG,YWHAH,CRBN,NME2,YWHAB,HSPB1,PEBP1,TERT,HSPA8,OIP5,FBXW7,HSPA5,PIP5K1A,UBA52,PSMC4,UBLCP1,MAP2K1,HSP90B1,WWP1,ARMCX3,PAK2,JUP,ZNF189,BAD,FKBPL,PHKB,PTEN,TXNDC12,PRKCE,CTSB,PRDX2,SRC,VIRMA,GNAI2,UBB,SFN,AKT1,BRAP,RHEB,ATP5F1A,HSD17B3,YWHAZ,PIP4K2C,SDF2L1,SPOP,DNAJB6,STK11,HSP90AA1 |
| 9.428e-06 | -11.57 | DDX17 (DEAD-box helicase 17) | protein interactions | 10521 | 376 | 144 | 19454 | 5460 |
RCHY1,SYNCRIP,TOP1,FZR1,CAND1,CDC5L,ZBTB2,CDK9,TMPO,MBD5,MDM2,CD81,COPS5,CSNK2A1,HDAC6,SNRNP70,FAF1,NOSIP,DHX9,HNRNPK,NEDD8,SMN1,MEPCE,TP53,FBP1,WBP11,MAP1LC3B,EEF1A1,TFCP2,NUPR1,ILF2,EIF4A3,PSPC1,CCNF,NDN,CNTNAP1,AR,USP14,PPP1CC,FBXO7,PRKACB,RUNX1,IVNS1ABP,RC3H2,NIF3L1,RBM7,UBE2H,NRP1,NLE1,TRIM3,BAP1,RPA3,RNF113A,KIN,FBXW7,DGCR8,HDAC3,HSPA5,PIAS1,SF3A1,CDK7,METTL14,RPA2,P3H1,HNRNPH3,HEXIM1,RARS1,SRSF1,RBM5,PHB1,EED,MAP1LC3A,SUMO2,HNRNPL,DHX15,CHMP2A,WWP2,PDIA3,DDRGK1,GAS8,CTNNB1,HNRNPA1,YWHAG,XPO1,AGR2,TRAF6,MAGOH,RB1CC1,HNRNPD,DDX1,CBL,MAEA,HSPD1,PCNA,EWSR1,PRPSAP1,TNF,CBLL1,HNRNPDL,SSRP1,SUPT5H,TXNRD1,B3GNT2,LGR4,ISG15,SOX2,CHMP4C,EZH2,CMTR1,SF3B4,SNRNP40,MATR3,CUL2,CUL3,CREBBP,MYC,SNRPB,BTF3,PSMD14,BRCA1,DCAF4,ILK,COP1,ICAM1,XRCC5,WBP2,FOS,SNRPA,DDX39B,DDX5,EP300,HDAC5,HSPA8,TRUB1,STAU1,FXR2,UFL1,HSCB,PYGB,MTF1,EMC9,PPARG,PIH1D1,RTF2 |
| 9.454e-06 | -11.57 | WDR82 (WD repeat domain 82) | protein interactions | 80335 | 198 | 84 | 19454 | 5460 |
SOX2,MAP1LC3B,RAF1,CCT5,SUPT5H,PPIL3,TP53,RNF8,TAF2,DDX42,FAM76B,PPP1R12A,RBM3,MEPCE,RIGI,SSRP1,KRAS,HUWE1,TTC4,CSNK2A1,XPO1,HNRNPA1,PPIL4,ZMYND11,GMPPB,NDC80,PFDN5,DPY30,SNRNP70,FABP5,PHB1,CDK9,CCT7,FZR1,HNRNPL,OCRL,TOP1,MIF,TCP1,PPP1CB,SF3A1,NUFIP2,MFAP1,HEXIM1,DYRK2,TOX4,RPA2,BIRC2,SF3B1,HSPA8,MAVS,SQSTM1,EP300,SNRPA,RPA3,HCFC2,IRF3,CXXC1,STAU1,RBM15B,SNRPB,PPP1CC,USP14,MYC,AAMDC,CUL3,CDC73,SMAD2,OSGEP,PFDN6,UBE2H,RIT1,GLOD4,CCT2,ATG3,RC3H2,PRMT5,CSNK2B,PSPC1,CCNF,CTTN,PPP1R10,POLR2B,ESR2 |
| 9.454e-06 | -11.57 | NDC1 (NDC1 transmembrane nucleoporin) | protein interactions | 55706 | 198 | 84 | 19454 | 5460 |
MAPRE1,NTRK3,BRCA1,RHOB,LMNB1,CIAO1,RAB11A,RAB2A,MYC,SEC63,APLNR,RHOJ,COPE,UBE2I,SEC61B,RAN,DPEP1,LMBR1L,SSR1,LMNA,RPA2,ST7,OTULINL,RND2,YIPF5,CDC42,SEC62,TSPAN5,PXMP2,STX7,SLC25A51,LPAR1,IRF7,HSCB,SLC7A1,AKAP1,RAB5A,DERL1,EMP3,RAB9A,SYVN1,TSPAN15,RPA3,CXCR4,UPK1A,ESYT1,RHOG,LAMP3,LRRTM1,RAB5C,SLC25A46,LAMP2,MDFI,IFI16,NUP35,LMAN1,TMPO,STX6,EGLN3,RHOH,DNAJC1,ARF6,SPPL3,RAC2,SPINT2,GJA1,HSD17B11,PTPN1,RAB35,GNAI3,CRELD1,RAB4A,STIM1,RPN1,DNAJC25,NUP153,FKBP8,SAR1B,RAB3B,KRAS,NUP107,IGF1R,TMT1A,CYP2C9 |
| 9.544e-06 | -11.56 | biological process involved in symbiotic interaction | biological process | GO:0044403 | 262 | 110 | 18204 | 5365 |
WWP2,SLC7A1,ICAM1,CCL5,CHMP1A,SLC20A2,PAIP1,CDC42,CD86,CAMP,PPIA,VPS4A,SAP30BP,HSPA8,PPIB,CDK1,PPID,CLDN6,SRC,INPP5K,CHMP1B,DAG1,HSPD1,HTR2A,LDLR,CCL3,JUN,RAB9A,ITGAV,CFL1,NECTIN2,RNASEK,CCL8,EEF1A1,SMARCB1,GAPDH,IFI27,CAV1,PC,CHMP2A,MOG,CHMP2B,CD80,HSP90AB1,VPS18,CHMP5,MYD88,WWP1,F11R,CD81,APOBEC3H,STOM,CD4,IDE,CLDN1,CHMP4C,SP1,CD46,ROCK2,CD209,EP300,ROMO1,RPSA,SAP30,GPX1,PHB1,CLDN9,TFRC,LAMP3,TRIM62,RAB29,CX3CR1,HYAL2,TUSC2,AVPR1B,EPHA2,VAMP8,AKT1,MBL2,ZDHHC8,ITGB5,ITGA2,PLG,GPR15,CXCR4,VPS4B,CAV2,CTSB,NRP1,CDK9,TSG101,TAF11,NLRP6,ZBED1,TNFRSF14,NUCKS1,MRC1,CBL,MIR222,CCR5,RAB5A,SIVA1,JPT2,PLSCR1,F2,PSMC3,MIR221,DPP4,BECN1,NUP153 |
| 9.549e-06 | -11.56 | MYO1C (myosin IC) | protein interactions | 4641 | 370 | 142 | 19454 | 5460 |
TADA3,TLR9,PPTC7,PNPO,ATP1A1,EPHA2,CIAO1,SMARCA5,AR,PPP1CC,CFL1,CFL2,ARHGAP21,COPE,DAPK1,TMOD3,RALA,CTSB,DYRK1A,DEK,VIRMA,SH3BGRL,CTTN,CCNF,PTEN,MOB4,GRM2,RPA2,LMNA,TMOD1,PRKCA,SPTBN1,RBFOX2,CDK7,CFTR,CDC42,CD2AP,FBXW7,HSPA5,SIRT7,RPA3,SHC1,STYK1,TMOD2,RBM17,DPP4,HDAC6,CGAS,ARF6,PTP4A3,CDK9,TMPO,ACTA2,HACD3,TIMM8B,TES,RAC2,ADD1,DSTN,CAPZA2,ARPC3,TFCP2,NUPR1,FURIN,TP53,FBP1,MAP1LC3B,RIGI,FBXO25,DUSP21,PPP1R12A,RAB27A,SEPTIN7,MYO6,RHOB,LAMTOR1,CDKL2,POLR1B,SP1,COP1,CUL3,RRN3,PYCARD,MYC,BTF3,RIOK2,STAT1,APEX1,CHCHD3,PPP1R3C,DLST,GTF2F1,SMU1,AGGF1,TIMM29,ELK4,TIMM13,PPP1CB,STAU1,SRSF2,FBXO30,UNC45A,SAP18,FOS,BMPR1A,DDX39B,AKAP1,COMMD2,HSPA8,SF3B1,TXNL1,AGR2,RHOG,BCL2L1,CBL,WWP2,BAZ1B,CTNNB1,KCTD10,RHOH,TRIR,SPTAN1,RMND1,STK3,EGLN3,CCDC127,RBM5,RAB35,CORO1C,EZH2,B3GNT2,TOP3B,CSTF2T,ISG15,ACTN4,SOX2,TRIM37,TNF,PSMA1,LASP1,CCAR1,MYO1B |
| 9.639e-06 | -11.55 | ANKRD55 (ankyrin repeat domain 55) | protein interactions | 79722 | 227 | 94 | 19454 | 5460 |
BOLA2B,PHB2,EEF1G,HSPA8,ATP5PO,FRS3,SLC25A3,ACTB,TUBB,ATP5F1B,RPL10,VDAC2,RPS9,PRMT5,YWHAZ,LMNB1,CKB,SERPINH1,HSP90AA1,MCM3,ETFA,RUVBL1,NAT9,MCM6,CCT8,SLC25A5,HSPD1,RTCB,PCNA,CDK5,RPN1,TUBB4B,HGS,EEF2,PPP2R1A,ATXN10,TCP1,CCT7,HSP90AB1,PHB1,RPL9,DNM2,WDR6,YWHAB,PPP3CA,RPL23,RAB5C,PFDN5,YWHAG,XPO1,YWHAH,RPL4,PDHB,HSPA5,MARS1,SSR1,HSP90B1,ACACA,RPLP0,RARS1,ZSCAN1,NTPCR,PYGM,TUBA1B,EIF4A3,RPS3,GANAB,TRIM23,XPOT,ATP1A1,OAT,RPL7A,SLC25A1,ZMYND19,TUFM,CFL1,SRPRB,FARSA,KPNA2,CSE1L,ARF4,SFXN1,SLC25A11,DHX9,IFT52,RPL3,PSMC3,EEF1A1,CAND1,SLC25A12,COQ8A,AIFM1,RPS2,GAPDH |
| 9.734e-06 | -11.54 | PSMB7 (proteasome 20S subunit beta 7) | protein interactions | 5695 | 201 | 85 | 19454 | 5460 |
TPM3,PSMD3,USP15,PSMD10,PSMD7,UBE2D1,PSMG2,PSMB1,PSMB4,PSMB5,PSME2,POLE3,MYL12A,SPTAN1,DYNC1I2,FZR1,RPS10,PSMB9,ISG15,INSIG2,CCT5,NAA15,PSMC3,RAD23B,UBE3A,ERO1A,PSME1,MAP1B,FKBP8,PRDX4,RIGI,PSMD12,RPS27A,MRPL22,CTNNBL1,PSMA2,RBBP7,PSMA1,PSMA5,HUWE1,KRAS,USP14,FBXO7,PSMD1,LDHB,PSMA4,PSMB2,PSMG3,RIT1,UBE2H,PIP4K2C,PSMD14,POMP,GANAB,PSMC5,PSMA6,LMBR1L,VIRMA,CLIC4,PSMB6,ADRM1,PSMD6,MBL2,TMOD3,LDHA,PSMD4,PAAF1,PSMB3,PSMC4,ACACA,PRKCA,UBE2M,PSMB7,DERL1,EMG1,PSMA3,SYVN1,PSMG4,PRPF4,IRF3,BAP1,SKP1,PSMC1,DDI1,DESI1 |
| 9.739e-06 | -11.54 | PLEKHM1 (pleckstrin homology and RUN domain containing M1) | protein interactions | 9842 | 55 | 31 | 19454 | 5460 |
CTDSP1,VPS33A,VPS18,MAP1LC3B,RRAGA,SERPINB9,PRR5L,TOP3B,STX7,VPS16,GABARAP,RRAGB,STX8,LAMTOR1,RHEB,VPS39,LAMP2,SEC13,LAMTOR2,VAMP7,GADD45G,VIRMA,MIOS,FAM98A,HNRNPL,TRIM54,VTI1B,RAP1B,EIF2S2,MOB4,PAFAH1B3 |
| 9.780e-06 | -11.54 | CCND1 (cyclin D1) | protein interactions | 595 | 280 | 112 | 19454 | 5460 |
JUN,PPP2R1A,RBPJ,CDK5,PCNA,BAG2,HSPD1,SLC25A5,CCT8,CDKN2C,MCM6,RFC2,TRMO,KRAS,XPO1,ATG7,CTNNB1,UBXN6,DPY30,AHSA1,CDKN1B,CDH13,SKIC8,KDM2A,XPO5,KRT8,FBXO31,CCT7,IFI27,NOP58,HNRNPL,CCAR2,ATXN10,PPP1CB,CDKN1A,WDR77,DMTF1,PAFAH1B1,TOR1AIP2,CRYAB,CTBP1,PCLAF,HSPA8,EP300,HADHA,RFC4,FOS,CCND3,SKP1,TSR3,RFC5,MLF2,MCM3,CREBBP,CUL3,HSP90AA1,SP1,RIT1,DNAJB6,POLR1B,CCT2,BRCA1,LMNB1,CHTOP,PRMT5,SMU1,USP5,RBBP4,SNRNP40,EEF1A1,MAP1LC3B,CD2BP2,SMAD1,PPP3R2,TP53,CCT5,CDK4,CAMK1,CDK8,ABCE1,MSH6,CSE1L,ERCC3,USP2,TDRD7,PSMD7,MYBL2,RB1,CDK6,MDM2,CDK9,TMPO,FZR1,ARF6,GTF3C4,IGFBP3,CCNA2,BRINP1,CCND1,CDK1,LMNA,SQSTM1,NLE1,IDH3A,HDAC3,RUNX1,PPP1CC,AR,NONO,CREB1,PSMA6,KLK9 |
| 9.837e-06 | -11.53 | HLA-A (major histocompatibility complex, class I, A) | protein interactions | 3105 | 283 | 113 | 19454 | 5460 |
TAX1BP1,LMBR1L,DLST,CYB5R3,LAMTOR1,RHOB,NTRK3,ILK,MYC,RAB11A,EMC1,HSCB,GPC1,ZDHHC17,STX7,BMPR1A,TMEM106B,TAPBP,PMAIP1,RAB5A,EP300,ADSS2,BET1,RND2,SEC62,LILRB1,RHOH,BUD31,DIRAS3,EGLN3,CD1A,FOLR1,RAB35,PHB1,GJA1,RHOG,CBL,LAMP2,IFI16,PDIA3,RAB5C,PTPN5,G3BP1,KRAS,TAPBPL,IMMP2L,HS2ST1,TMT1A,EZH2,RPN1,RAB4A,RND3,RAF1,B3GNT2,DNAJC25,CTSB,RHOJ,UBB,VIRMA,DEK,SRC,CCNF,DNASE1L1,SEC61A1,SPOP,NRP1,UBE2H,RAB2A,DNAJC5,B2M,RPA3,RHOU,ITM2B,SYVN1,DERL1,RAB9A,RPA2,GPR35,FGFR1,MET,SCLT1,PRKCA,SHOC2,TRAM1,CDC42,ARF6,PRNP,LMAN1,CDK9,STX6,CAV1,COQ8A,HRAS,HSD17B11,RNF128,RAC2,ESYT1,DPP4,CALR,FAM20C,EMC4,LAMP3,TOLLIP,CD1B,EMC2,IGF1R,TFRC,SFTPC,MAGEA4,IL20RB,FURIN,MAP1LC3B,CLEC2B |
| 9.837e-06 | -11.53 | vacuole | cellular component | GO:0005773 | 857 | 306 | 19108 | 5553 |
ATG9A,SNAP23,RAB5C,SLC2A8,ATP6AP2,OPTN,MCOLN1,SNAPIN,CHMP2A,FCMR,RAB9A,CDIP1,LAMTOR2,TLR7,TMEM74,HEXA,RAB29,TLR9,CPNE1,ATG16L1,TBC1D25,TRIM32,AP2M1,SPHK2,PCSK9,ATP8A1,RAP1B,MMD,GPC4,ACP2,LAMP3,HSPA8,GNB1,VPS39,RAB3A,BACE1,LAPTM4A,TTR,DRAM1,VPS4A,ACP5,PADI2,ATP6V1G1,SYNGR1,HEBP2,HPS6,TICAM1,VPS16,TOM1,LAMTOR1,CTSC,GCA,LMBRD1,SRC,VPS18,GDI2,CRYAB,CHMP2B,STX17,TMEM30A,PLD3,SLC38A7,RAB37,LRRC8A,GNA11,VAMP7,SEC13,TMEM45B,TMEM165,TFEB,PLAAT3,FLOT1,NRBF2,GALC,TRAF3IP3,TLR3,RAB27A,FABP5,BRI3,CLCN6,TAX1BP1,ENPEP,FASLG,SURF4,ATP6V1D,RAB3D,USP5,SNX1,AP1M1,AP2A1,RNASEK,C9orf72,VLDLR,THBD,STARD3NL,RAB9B,SDCBP,MAP1LC3A,CXCR4,ATP6V1G2,GNAI3,SFTPD,TOM1L1,DNAJC5,RAMP3,ADRB2,RRAGB,TFE3,TASL,ABCB9,AP2S1,PSMD1,UBA52,GNPTG,OCIAD2,CAPN1,SIAE,BORCS6,TMEM97,AGA,SLC35F6,PLAC8,KXD1,RB1CC1,MINAR2,TMEM179B,KLHL22,AP5M1,MLC1,VMP1,DSN1,TUBB,GABARAP,PLA2G5,MARCHF9,GABARAPL1,MITF,TNFAIP3,NPC2,EEF1A1,CFTR,CD1B,SRGN,SNX2,SLC22A17,CD1E,CALR,OCRL,USE1,TBC1D5,CTSB,GGH,PIP4P1,CD1D,LYZ,VAMP1,SLC7A14,BCL10,VTI1B,CHMP1A,TRIM29,BORCS8,HSP90AA1,TBC1D17,TRAPPC1,RAB23,MYO6,CYB5R3,RNASET2,CHMP4C,ARRDC3,SESN2,YWHAB,OSTM1,ATRAID,TLR8,PIP4K2C,VAC14,GPR137,CTSK,WDR11,FMOD,EVA1A,MREG,SAR1B,CHMP5,NDUFC2,AP5S1,SLC17A5,FLCN,CD1C,TRIM21,LUM,NEU1,SLC38A9,AP1S2,PPT1,LDLR,SERPINA3,CRHBP,B2M,GLIPR1,CHMP1B,ATP6V1A,TMEM203,TP53INP1,DNAJC3,SH3GLB1,PRELP,BLOC1S2,CHID1,FTH1,CD63,PYCARD,ACTR2,SDC4,PIP4P2,KLC2,PLA2G15,PRCP,TNFAIP8L2,TMEM59,CMTM6,CYB561,SLC48A1,TM9SF1,BORCS5,BECN1,MAP1LC3B,TAB2,TMEM106B,TRIM23,RETN,TP53INP2,CYBRD1,KICS2,CCT2,ATP6V0B,SQSTM1,TMBIM1,MIOS,CD164,HYAL2,CCT8,HGS,RHEB,ENTPD4,MTMR2,B4GALT1,RNASE6,NCSTN,RNF152,OGN,RAB2A,IFNAR1,VPS33A,CTSA,DPP4,LAMTOR3,GABARAPL2,IL1B,CAPN2,RAB14,RRAGA,GNB4,HEXB,BST2,SERPINB1,PSEN1,RNF167,FAF2,CD34,LITAF,MARCHF3,PRDX6,SNX14,SLC11A2,STX7,TUBB4B,ABHD6,LIPA,LAMP5,CTSD,STOM,ATP6V1C1,UBXN6,TMEM199,NSG1,GNAQ,FTL,NAPG,PYGB,ATP6V0E1,CDC42,SDC2,ZNRF1,TMEM208,GPC1,VAMP8,TEX264,SNAP29,BORCS7,PLEKHF1,TOLLIP,VPS26A,LAMP2 |
| 9.894e-06 | -11.52 | PAXIP1 (PAX interacting protein 1) | protein interactions | 22976 | 349 | 135 | 19454 | 5460 |
ELF5,PPARG,MED23,MT2A,STAU1,PHB2,TRA2B,SRSF2,EP300,FOS,RFC4,H1-10,CIRBP,CUL3,LDHB,PKP4,HNF1B,ESR2,ERH,UMPS,LGALS3,PRMT5,PELO,AAMP,SKA3,SOX2,GCLC,TOP3B,FEN1,PAX6,RFC2,RPS27A,SRSF4,MCM6,RBBP7,G3BP1,SRSF7,PRPSAP1,LHX2,DRG1,POU5F1,CDC23,LRATD1,SCAMP5,DDX23,DIS3L,TRA2A,XPO1,DPY30,STOML2,BABAM1,NPC2,SRSF10,PPIA,SNRPD3,AASDHPPT,LYAR,HP1BP3,FAHD1,S100A8,WDR82,NXT1,SRSF1,KLF4,NOL7,PAX9,CYB5R4,CXXC1,CLU,PIAS1,FBXW7,EIF5B,NME4,PRDX6,PPIH,PML,NBN,HCFC2,SMAD2,ANAPC4,ATP1B3,PPP1CC,AR,RUNX1,HSPA14,CDC16,VIRMA,CDC20,TECR,SNX3,ZNF622,LDHA,COPE,BUB3,RPS20,CSNK2B,PHAX,MOB4,EIF2S2,FBLN5,PSMA6,NUPR1,MRPL33,PGM1,SOX9,CD2BP2,EGR2,H2AX,TP53,COMTD1,MDC1,CAPZA1,PAGR1,THRAP3,H3C1,PPP1R12A,CDK12,SNRNP70,ATP1B1,TPM3,CSNK2A1,IRF4,PCYT1B,CDC5L,NOP9,DKC1,CDK9,TMPO,MYL12A,MAPRE2,SELENOV,ZNF280B,KRR1,ALYREF,RPL12 |
| 9.975e-06 | -11.52 | EPB41L5 (erythrocyte membrane protein band 4.1 like 5) | protein interactions | 57669 | 292 | 116 | 19454 | 5460 |
RND2,KLC2,ATP5IF1,IMPACT,SPECC1L,COIL,STX7,HSCB,STAU1,MCM3,MYC,SFN,RAB11A,H1-1,LAMTOR1,MRPS25,RHOB,LRRC1,MIDEAS,CMTR1,RPL19,KBTBD6,APEX1,RPL35,H1-3,TRAF2,RAF1,RND3,GPBP1L1,NLRP2,RAB4A,PDIA6,RPL31,NEK9,GCA,POLDIP3,SSRP1,FLOT1,KRAS,YWHAH,YWHAG,CTNNB1,NT5C2,PRDX1,LAMP2,RAB5C,ZCCHC10,YWHAB,H2BC17,RHOG,DCAF5,GJA1,RAB35,SRSF1,DIRAS3,RPS10,TTC9C,LYAR,RHOH,AASDHPPT,CDC42,DENND2D,FGF13,RPLP0,ARL15,HECTD1,TWNK,HMCES,RNF113A,RHOU,CXXC1,CDC42EP4,DGCR8,NPM3,DNAJC5,RAB2A,RPL7A,CIAO1,SMAD2,YPEL5,ALKBH5,ATP1B3,PIP4K2C,RC3H2,FGFBP1,PRKRA,SYT2,ACOX1,RPS3,CYRIB,RPL22,PYGM,RPL13A,RHOJ,DDX39A,RPSA,CASK,RP9,RPL3,NTRK2,CAMKV,TTC4,LAMP3,GMPPB,LANCL2,NAA30,RAC2,CDK6,SMAD3,HRAS,SSU72,KRR1,DBT,STX6,CAV1,ARF6 |
| 9.987e-06 | -11.51 | STX10 (syntaxin 10) | protein interactions | 8677 | 109 | 52 | 19454 | 5460 |
SCFD1,NAPA,RHOB,STXBP6,LAMTOR1,STX16,VAMP5,RAB11A,ESR2,ARMC6,RHOJ,TMEM74,VAMP3,RPA2,RND2,OTULINL,CDC42,BET1,SEC22B,ATG16L1,STX7,NAPG,RAB5A,RPA3,RHOU,STX1A,RHOG,LAMP3,RAB5C,LAMP2,ATG9A,STX6,RHOH,VTI1B,RAC2,NRSN1,COQ8A,STX12,RAB4A,TMEM204,TFRC,MAP1LC3B,LPAR6,TMEM101,SNAP29,RAD21,PDE2A,STX11,KRAS,STX18,STX8,RUSF1 |
| 1.001e-05 | -11.51 | THAP12 (THAP domain containing 12) | protein interactions | 5612 | 101 | 49 | 19454 | 5460 |
ESR2,RPL10,RPL19,RPL35,RPL13A,PRKRA,KIAA1958,EIF2AK2,RPS3,MRPS25,ZNF668,CUL3,RPL7A,LRRC73,TMED5,LDOC1,NPM3,MAPKAPK3,DNAJC3,ZNF574,MRPS34,APOBEC3C,FGF13,NOTCH2,RPS14,SURF6,STK3,PRNP,RPS10,RPS16,EIF2S1,PRR3,KRR1,SRSF1,CDR2L,RPL8,RPS2,STK4,HNRNPA1,RIGI,SRSF4,MRPS17,KRAS,SRSF7,RPL3,ZNF526,APOBEC3D,RPSA,TP53 |
| 1.001e-05 | -11.51 | KNL1 (kinetochore scaffold 1) | protein interactions | 57082 | 101 | 49 | 19454 | 5460 |
VIRMA,CDC20,SNRNP40,BUB3,PHF21A,BAD,CRYBB3,COP1,PSMD14,FBXW11,DCAF4,RC3H2,BRCA1,AR,PPP1CC,CIAO1,MLF1,MYC,DSN1,VPS28,KDM1A,MIS12,PML,NLE1,RPA3,LSM2,RPA2,DET1,RFXANK,ATG16L1,CDC5L,NUF2,NAA11,EGLN3,DNAJC7,GAPDH,HSPB8,NDC80,PDIA3,UBXN6,MDC1,SOCS2,KRAS,RBBP7,BAG2,CBX3,SOX2,ETFB,SPC24 |
| 1.003e-05 | -11.51 | regulation of muscle hypertrophy | biological process | GO:0014743 | 72 | 39 | 18204 | 5365 |
PPARA,MIR21,HAND2,SMAD4,BECN1,TOMM70,IL6ST,TRIM63,PPARG,MIR34C,G6PD,ADRA1A,PI16,MIR25,RGS2,LMNA,PRKCA,TNFRSF1B,MIR208A,MIR20A,PDE9A,MIR17,PPP3CA,MIR214,CAV3,MSTN,ROCK1,MEF2A,MIR145,GSK3A,MIR1-1,MTPN,SMAD3,ROCK2,PARP2,ATP2B4,MIR34B,IGF1,FOXP1 |
| 1.003e-05 | -11.51 | LUC7L2 (LUC7 like 2, pre-mRNA splicing factor) | protein interactions | 51631 | 337 | 131 | 19454 | 5460 |
KRAS,RBBP7,TRIM37,RUVBL1,RPS4X,NAT9,PABPC1,PCNA,RPAP3,RUVBL2,SRSF8,SRSF7,EZH2,ZRANB2,SNRPE,RPL18,RPS23,RAF1,E2F4,PAIP2B,FAM98A,PAIP1,SNRPD3,DYNC1I2,ZNF593,SRSF10,FOLR1,SRSF1,PHB1,PBDC1,PSMD10,ZCCHC10,YWHAG,DDRGK1,EXOC1,TRA2A,CTNNB1,TRA2B,PTN,UFL1,STAU1,FTL,SAT1,APPBP2,DDX5,PIH1D1,ATP6V1C1,ZC3H14,NEK7,FBXO22,RBBP4,PSMB6,GADD45G,ESR2,RPL19,SNRPD1,SNRPD2,AP2M1,RPS9,COP1,MYC,NFYA,CFAP20,CUL3,SFN,PIK3R3,HUWE1,SNRNP48,CDC40,THRAP3,SRSF12,MEPCE,SNIP1,MRFAP1,IK,FBP1,CDK4,MAP1LC3B,LBR,RPL15,SPPL3,CAND1,RPS16,NKAP,NAP1L5,SYNCRIP,CRBN,SNRNP70,BRD3,CMSS1,MOV10,CSNK2A1,COPS5,CD81,PPIL4,SMC4,RBM22,HSPA5,BAP1,RPL27,DDX46,KIN,SQSTM1,ARFIP1,RNF113A,LUC7L3,MTRES1,SF3A1,SNRNP27,FTH1,ADRM1,PPP1R10,RPL22,SRPK2,VIRMA,CCNF,CTTN,EIF2S2,PHAX,MOB4,CSNK2B,ALB,STK24,IVNS1ABP,RC3H2,PEA15,CASC3,CARS1,RPL7A,TIA1,USP14 |
| 1.004e-05 | -11.51 | ALDH3A2 (aldehyde dehydrogenase 3 family member A2) | protein interactions | 224 | 298 | 118 | 19454 | 5460 |
CAPZA2,MTCH2,CCDC47,FKBP8,SLC6A8,RAB3B,HUWE1,IGF1R,STYK1,DNAJC7,ESYT1,COPS5,LAMP3,SLC25A46,ATP5MG,ADIPOR2,EDEM1,FAM20C,STX6,TMPO,LMAN1,FZR1,CAND1,DNAJC1,RAC2,HSD17B11,PTPN1,COQ8A,AIFM1,FGFR1,SSR1,RPA2,LMNA,ST7,SMYD3,CDC42,CCND1,TOMM20,RTN4,RAB9A,DERL1,SYVN1,NCDN,RPA3,MME,MAPRE1,CIAO1,SEC63,VIRMA,UQCRQ,ARMC6,NDN,INTS12,CCNF,RHOBTB1,PTRH2,RAB4A,RPN1,STIM1,EZH2,FAF2,DNAJC25,ARFGEF1,SACM1L,G3BP1,TMT1A,CYP2C9,ARMC8,DCAF11,PEX3,CBL,HAX1,RHOG,DDRGK1,RAB5C,MARCHF5,MAPK4,LAMP2,COX14,CEP19,TMEM237,RHOH,GJA1,PHB1,RAB35,SLC25A3,VAPB,SEC62,OTULINL,RND2,MTX2,PGRMC1,ATP6V1C1,TOMM22,STX7,PXMP2,RER1,HSCB,UFL1,PMAIP1,RAB5A,AKAP1,HSPA8,EXD2,TMEM106B,FIS1,NTRK3,YWHAZ,LMNB1,LAMTOR1,RAB11A,CUL3,MAD2L2,ESR2,ANAPC2,SEC61B,RMDN3,LMBR1L |
| 1.006e-05 | -11.51 | PER2 (period circadian regulator 2) | protein interactions | 8864 | 139 | 63 | 19454 | 5460 |
MCM3,PCCB,RPL39,HSP90AA1,FBXW11,YWHAZ,CCT2,CSNK2B,ENO1,CYB5R3,VIRMA,TAGLN2,MATR3,LMO4,TPT1,SPR,PIP5K1A,PSMC4,ACACA,HNRNPH3,PRKCA,HSP90B1,LMNA,H2BC11,HADHA,HNRNPH2,APPBP2,PGK1,CRY1,PML,PRKD3,APMAP,HNRNPA1,SAV1,HMGA1,SMCHD1,NME2,SYNCRIP,CCT7,G6PD,SLMAP,MDM2,EEF2,AURKAIP1,JUN,ACTN4,ASPM,TP53,TOP3B,UBL4A,CSNK1E,CIBAR1,NME1,TFRC,PDIA6,HSD17B10,SEPTIN7,ERO1A,CCT8,HNRNPA2B1,RAB1A,EIF3E,VDAC1 |
| 1.016e-05 | -11.50 | TMEM87A (transmembrane protein 87A) | protein interactions | 25963 | 184 | 79 | 19454 | 5460 |
S1PR4,EDNRA,SYNGR1,KLK6,OAF,FBXO22,B4GAT1,APLNR,RAB11A,GPR17,GPBAR1,SCN3B,CSK,RAB2A,TIMP1,RHOB,LAMTOR1,SYP,TSPAN15,RAB9A,SPCS2,RAB5A,VIPR1,LPAR1,NPTN,STX7,TSPAN5,BET1,GLRA2,EDEM3,CDC42,OTULINL,RND2,SIGMAR1,OXSR1,RAB35,SRP14,HRAS,CHID1,RAC2,GJA1,ADAM21,RHOH,SNX1,PCSK9,ARF6,CAV1,DUOXA2,STX6,DIRAS3,TOR1B,LMAN1,RAB5C,LAMP2,KLHL22,CCR6,LAMP3,CRTAP,RHOG,P2RY1,AGPAT1,UPK1A,TMT1A,ATP5PF,PC,TSPAN17,RAB3B,KRAS,LAMB2,SLC7A14,EDEM2,ARFGEF1,TOR3A,DDX39A,SFTPC,RAB4A,RPN1,TFRC,CPE |
| 1.022e-05 | -11.49 | MRPL19 (mitochondrial ribosomal protein L19) | protein interactions | 9801 | 167 | 73 | 19454 | 5460 |
HSCB,MRPL17,TMEM177,TRA2B,MRPL57,MRPL41,MRPL40,NHP2,MRPL20,RPA3,NGRN,GFM1,RPA2,MRPS18A,MTRES1,MRPL10,RBMS2,MRPL12,MATR3,MRPL23,RPL13A,ESR2,TACO1,MRPL53,CCDC90B,MTG1,MRPL13,FBXW11,UBE2H,AUH,MYC,CUL3,PMPCA,MRPL16,TUFM,H1-6,TRIM63,MEPCE,FASTKD5,HNRNPDL,HSPD1,MRPL52,HINT2,COX8A,PDHA1,GFM2,MRPL49,MRPL51,MRPL47,MRPL11,CENPM,AURKAIP1,SOX2,ANAPC13,METTL15,CAND1,PRNP,MRPL50,SRSF10,MALSU1,MRPL24,SSBP1,GATD3,MRPL18,RHOG,TMEM70,SNRNP70,MRPS26,GRSF1,MTRF1,MRPL9,HNRNPA1,TRA2A |
| 1.022e-05 | -11.49 | OTULIN (OTU deubiquitinase with linear linkage specificity) | protein interactions | 90268 | 167 | 73 | 19454 | 5460 |
CYB5R3,SF3B6,CCNF,PTEN,RMDN3,GSK3A,STAT1,EIF4A2,USP5,SUSD6,MAT2A,TRIM32,PRPF31,BRAP,OTUD7B,HMGCS1,MRPS25,MRPS16,CALU,THOC6,PFDN4,ICAM1,IRF3,DUSP9,ATP2C1,CXCR4,UGDH,DVL2,RPA3,HSPA8,PAFAH1B2,EIF5B,UCHL3,PGRMC1,DUSP14,ETF1,CFTR,HCST,RPA2,ACACA,NDUFA5,STT3A,PSMB1,TES,DSTN,CCAR2,TOMM70,CACYBP,EGLN3,USP3,ACOT8,SYNJ2BP,LAMP2,SPATA2,CSNK2A1,HDAC6,BCL10,DDX23,OSBPL8,MAP1B,FAM168A,ERP29,RBCK1,TNF,CD80,NEDD8,TP53,RRM1,GFPT1,TUBA1A,NHERF1,CYB5B,OTULIN |
| 1.031e-05 | -11.48 | regulation of protein transport | biological process | GO:0051223 | 433 | 169 | 18204 | 5365 |
SUFU,JUP,CPLX1,SNX3,MIR148A,HDAC3,GNAZ,PIK3R2,PCK2,PLCB1,RBM22,PIK3R1,PKIG,RAN,MIR146A,PSEN1,CAMK1,CD81,HADH,ATP2C1,SCFD1,PPARG,SFN,SYT4,SLC16A1,CHCHD4,SAR1B,MAVS,IFI27,ACHE,EFNA5,LYPLA1,CD36,FKBP1B,CDK1,PPID,ANGPT1,UQCC2,HSPA8,DMAP1,PTPN1,UHMK1,IL12A,SRC,KCNJ11,PDCD5,SNAP25,PARD6A,TLR4,VEGFC,LEP,LRRC8A,CD200,OPRM1,TM9SF4,HSP90AA1,PTPN11,IL12B,WWP2,TMEM30A,UBAC2,IFNG,KCNB1,TIAM1,MDM2,CCL5,ACSL4,ACVR1C,PGRMC1,DYNLL1,RAB23,OAZ1,IL13,GNAO1,CDC42,PPIA,OAZ3,EFCAB7,IL6,NEO1,ARFIP1,SFRP1,CSK,RSAD2,ERP29,SLC12A2,ANP32B,NDFIP1,BAG3,TLR2,NLGN2,GHRL,SNX12,CD2AP,CFTR,CD38,CNR1,CARTPT,UFM1,PICK1,F2,EDEM2,C2CD2L,TMEM97,ARF6,OS9,NR1H2,SYBU,DNAJC1,JAK2,HCLS1,EDEM1,TSG101,OR51E2,CHRM1,VAMP2,GNA11,SRI,LCP1,SUMO1,P3H1,BAD,PRKCB,CHRM3,PRKCE,CHGA,STX1A,TGFB3,CDK5,GOLPH3L,IL1B,DERL2,CTDSPL2,VPS28,UBE2G2,PPP3CA,DPH3,DRD3,PFKFB2,ADTRP,PKIA,OAZ2,PRR5L,NDUFAF2,SIRT7,OSBP,IL1A,TGFB2,XPO1,CHP1,SMAD3,PDCD10,APBB3,ENY2,TNF,ADIPOQ,SLC7A11,UCP2,SVIP,IGF1,EP300,JAGN1,ERLEC1,SELENOK,TXN,RAB29,HYAL2,CCN3,RHBDD3 |
| 1.032e-05 | -11.48 | SUPT4H1 (SPT4 homolog, DSIF elongation factor subunit) | protein interactions | 6827 | 60 | 33 | 19454 | 5460 |
PAK5,PPP4C,SUPT5H,SEM1,KRAS,SOCS2,SSRP1,EIF3E,SNRPA,XRCC5,ELOF1,RNF34,EWSR1,EP300,UBE2H,RIT1,MOV10,MYC,WWP2,YWHAH,CSNK2A1,TMA16,ATG7,YWHAG,EIF3D,TOP1,LRIF1,ESR2,APEX1,DOK4,CCDC71,POLR2F,GTF2F2 |
| 1.032e-05 | -11.48 | TBP (TATA-box binding protein) | protein interactions | 6908 | 239 | 98 | 19454 | 5460 |
TCEA1,SPATA25,SNAPC1,CXXC1,MEF2A,PIAS1,HMGB1,NF2,CFTR,EDF1,GTF3C4,NFYB,GTF2H4,SUPT7L,JUP,MSN,UBE2I,POLR3H,GTF2A1,PPM1M,DYRK1A,AR,ATF4,SUB1,TAF5L,EMILIN1,TADA1,TADA3,DHX9,RPL3,MNAT1,HNRNPK,H3C1,HUWE1,TAF1D,TP53,TAF2,SNAPC2,NFE2L2,RB1,GTF2B,MDM2,FZR1,GTF2E1,FOXP1,SSX2IP,TAF9,KIAA1143,GTF2A2,EP300,DR1,DDX5,FOS,FTL,EYA3,MSX1,CTBP1,ABCB1,GTF2F1,GTF2F2,POLR3B,NFKBIB,CPSF1,GNG12,TAF11,POLR2B,CBX5,DRAP1,CPSF2,BTF3,IRF1,RRN3,CREBBP,MYC,SETD7,SP1,BAX,RUVBL2,TRIP4,PAX6,GTF3C3,RUVBL1,GTF2E2,ELF1,JUN,MAX,TAF10,RBPJ,POLR2D,DCAF8L2,TRAM2,POLR2L,SIN3A,RAMP3,POLR3F,DBR1,FATE1,TAF7 |
| 1.034e-05 | -11.48 | Apoptosis | REACTOME pathways | R-HSA-109581 | 172 | 81 | 10285 | 3229 |
SPTAN1,STK26,PSMA2,PSMB6,PSMB3,PMAIP1,FASLG,PSMA4,SFN,PSMB11,PSMC5,LY96,PSMB10,PSMA5,PSMA3,PSMB5,H1-1,YWHAB,PSMC4,PSMD3,PSMB7,PSMB1,SATB1,TLR4,LMNA,UBA52,YWHAH,UBB,PSMD14,PRKCQ,H1-3,BAX,YWHAZ,PSMD7,DAPK3,ROCK1,PSMD10,DFFA,KPNA1,PSME1,BAK1,PSMB2,PSMD1,STK24,PSMA6,AKT1,AKT3,YWHAG,TICAM1,AKT2,ADD1,PSMD12,PSMC1,DAPK1,TLR3,RPS27A,LMNB1,PSMD4,TFDP2,PSMC3,FAS,TP53,CTNNB1,BAD,TRAF2,PSMA1,DYNLL1,PSMB9,SEM1,BCL2L1,GAS2,CD14,H1-5,TICAM2,BIRC2,TNFSF10,PSME2,PSMD6,HMGB1,PAK2,PSMB4 |
| 1.047e-05 | -11.47 | MTRF1L (mitochondrial translation release factor 1 like) | protein interactions | 54516 | 242 | 99 | 19454 | 5460 |
MTRF1,CLPX,STOML2,MRPS35,MRPL9,NDUFV2,MRPS26,GATD3,HNRNPL,NDUFS8,CHI3L1,HSDL2,ETFB,NUDT19,NDUFS6,PDHA1,NDUFA12,PREPL,HINT2,PDIA6,MRPS11,KGD4,ETFA,MRPS17,PMPCA,PYCR1,MRPL16,MRPS25,NOA1,TACO1,DLST,MRPL13,ATP5F1B,MRPL23,NDUFAF4,MRPL12,MRPS18A,NDUFA5,ATP5IF1,HADHA,NDUFS2,MRPS7,GRSF1,COX5A,TRMT5,MRPS9,SSBP1,COX4I1,MGME1,MRPL50,DBT,MRPL24,MRPS23,ATP5PB,MRPL47,NDUFA2,MECR,PPIF,HADH,BCS1L,NDUFS3,MRPL49,MRPL51,MRPL52,ATP5PF,MRPS18B,HSD17B10,PDE12,MRPS33,HSPE1,TTC4,MRPS18C,MRPL22,FASTKD5,NDUFAF2,PYCR2,MRPS16,OAT,MRPL53,MRPS28,ACAT1,COQ8B,TIMMDC1,MRPL10,MRPS34,QRSL1,MTRES1,TWNK,DLAT,GFM1,PDHB,NME4,MRPL17,MRPL41,MRPL40,GRPEL1,CRYZ,POLDIP2,MRPL20 |
| 1.052e-05 | -11.46 | ZRANB2 (zinc finger RANBP2-type containing 2) | protein interactions | 9406 | 187 | 80 | 19454 | 5460 |
SMURF1,UBE2V2,BCCIP,SRPK2,ACTB,SNRPD1,SRXN1,ZNF330,UBE2H,LMNB1,PIP4K2C,RIOK2,MYC,CFAP20,CUL3,COIL,TRA2B,SRSF2,UCHL3,HMGB1,CCDC86,TTC1,PMAIP1,RNF113A,EP300,NUBP2,BAP1,RPA3,UBE2M,EPHX1,RPL26L1,TBC1D17,DYRK2,LUC7L3,USP39,RPA2,CDK1,LMNA,LSM2,ATG16L1,ACTL6A,UBA52,EGLN3,AKAP17A,FZR1,TTC9C,OSBP,TOP1,TYMS,ARL4D,SYNCRIP,SWAP70,RSBN1L,YWHAB,DDX23,SNRNP70,CSNK2A1,DDRGK1,AHCYL1,G3BP1,PSMA1,H3C1,CAMKV,HNRNPK,HAPSTR1,EWSR1,SRSF7,SNIP1,RPL31,ZRANB2,CBX3,EZH2,NFKBIL1,UBE2B,FBXL7,DNAJC25,ZMYM4,RPL15,GTF2E2,B3GNT2 |
| 1.054e-05 | -11.46 | CPT2 (carnitine palmitoyltransferase 2) | protein interactions | 1376 | 65 | 35 | 19454 | 5460 |
SPRED2,COQ8A,MCL1,PTPMT1,GATD3,FAHD1,SSH3,KCTD10,EPHB6,APLNR,UQCRQ,RAB32,ATP5MG,TOMM40,ATP1B1,SMAD4,ATP1B3,TMEM70,KPNA1,NRP1,SLC25A10,RPA3,BAP1,MAIP1,NDUFA4,ARG2,AMACR,SYVN1,MTDH,HSCB,ATP5F1D,GTF3C3,RPA2,QRSL1,NDUFS3 |
| 1.054e-05 | -11.46 | COX17 (cytochrome c oxidase copper chaperone COX17) | protein interactions | 10063 | 65 | 35 | 19454 | 5460 |
EEF1A1,HADH,CDC42,TP53,SPR,LYPLA1,PMAIP1,COX17,ERG28,COA4,TCOF1,KATNAL1,SFXN1,SCYL2,SOD1,RAB1A,PEBP1,COA1,KRAS,AK3,CFL1,PRDX1,RIT1,AK2,ACAT1,CYB5R3,COMT,AIFM1,PLGRKT,COX14,LRIF1,TXNDC12,MIF,LGALS3,TXN |
| 1.056e-05 | -11.46 | PRKCA (protein kinase C alpha) | protein interactions | 5578 | 395 | 150 | 19454 | 5460 |
RPL10,PSMB6,SELL,ACTB,TRIM29,CAVIN2,STARD7,DLG4,NFKBIA,PIGK,BAD,GRIA1,H1-1,HSP90AA1,YWHAZ,LMNB1,FAS,TFDP2,GABRG2,PDE7A,MYC,RGS19,TNNT2,HAND2,PHB2,GPM6A,DDX5,TERT,EP300,TMEM185A,HSPA8,PPY,PEBP1,ANXA7,KLC2,EIF4B,ISOC1,SDC2,PSMB7,PPARG,STXBP1,LNX2,SYK,H1-5,CACYBP,PRKCQ,EIF2S1,GJA1,SDC4,PSMB4,HSPB1,PEX3,MGMT,CBL,IKBKB,CISH,CTNNB1,YWHAG,HSPB8,HR,HMGA1,IMMP2L,SACM1L,PRPS1,NRGN,H1-6,GJB1,KIT,PLCB1,EWSR1,PRPSAP1,PICK1,GTF2E2,KIF2A,GFPT1,H1-3,RAF1,SRC,VIRMA,SMURF1,EGLN2,NR1H2,PRKCE,F11R,SLC1A1,GSK3A,PITPNB,MAPRE1,ATP1A1,PEA15,IVNS1ABP,OGG1,FBXO7,GABRB3,PTPN11,TAS2R7,CCR3,RGS2,EIF4E,HMGB1,PFKFB2,NF2,CERS2,PRKCB,GRIA2,DVL2,RPA3,PARD6A,PRKCA,AVPR1B,HSP90B1,BTG2,LMNA,VPS4B,RPA2,CFTR,FTH1,EDF1,CDC42,PIP5K1A,SNAP25,GRM1,TES,ADD1,PTPN1,SHC1,TIAM1,CD9,SPP1,POLB,FCGR2B,HDAC6,MOV10,RIGI,RDH11,CYTH2,FBXO25,RBCK1,AKAP12,H3C1,SNAP23,SEMG2,SLC25A11,PALM2AKAP2,NFE2L2,NHERF1,PIK3CA,PPARA,TP53,UBL4A |
| 1.068e-05 | -11.45 | ZEB1 (zinc finger E-box binding homeobox 1) | protein interactions | 6935 | 170 | 74 | 19454 | 5460 |
APEX1,RBBP4,RPS9,GTF2A1,INTS10,RTRAF,RPS3,SERPINH1,IGF2BP1,SMAD2,H1-10,DRAP1,TUFM,RPL7A,USP13,CREBBP,HNF1B,HSPA5,G3BP2,RPL4,KDM1A,UCHL3,DDX5,NUP50,EP300,HSPA8,XRCC5,PPM1G,SLC25A3,RPLP0,CTBP1,KLF3,KLF12,RPS14,TCP1,RPL7,RPS16,CDK6,RPLP1,SYNCRIP,SMAD3,AIFM1,VCPIP1,RPS2,DDX1,E4F1,CSNK2A1,COPS5,MRPS35,RPL6,PRDX1,AHCYL1,PAX6,RPS13,RPS4X,G3BP1,TRIM26,HNRNPF,RTCB,DHX9,RPL23A,EWSR1,RPL3,PABPC1,SLC25A5,GTPBP1,ILF2,TUBB4B,CBX3,SMAD1,PPP2R1A,SOX2,TP53,IPO8 |
| 1.077e-05 | -11.44 | DYRK4 (dual specificity tyrosine phosphorylation regulated kinase 4) | protein interactions | 8798 | 32 | 21 | 19454 | 5460 |
STUB1,AIP,CALML5,RBBP4,FKBP8,HSP90AB1,PTGES3,FBXO25,TECR,PPP5C,CACYBP,CUL3,PPP1CC,ST13,CNP,FKBP4,DNAJB6,HAX1,DYRK2,HSP90AA1,ATP1A1 |
| 1.078e-05 | -11.44 | PPP6C (protein phosphatase 6 catalytic subunit) | protein interactions | 5537 | 213 | 89 | 19454 | 5460 |
SP1,HSP90AA1,ILK,RIT1,CCT2,BRCA1,MYC,PSMA4,CUL3,ESR2,RPL10,PSMD4,ACTB,BAD,LMBR1L,MAP2K1,PPP1CB,RPL27A,PGRMC1,SKP1,UFL1,EEF1G,NMRAL1,HSPA8,XRCC5,POU5F1,DDX1,XPO1,DDRGK1,PSMD3,EGLN3,ELK1,CCT7,HSP90AB1,CEP19,RPL7,TCP1,IGBP1,KRT8,RPL8,PSMB5,EEF2,RAF1,KRAS,TNF,PSMA1,LASP1,PSMA2,ETFA,CCT8,ATP1A1,UBE2H,GMPS,TUFM,RPL7A,GANAB,RPS3,CCNF,RPA2,PSMC4,MYL12B,HSPA5,MAVS,RPL27,BAP1,RPA3,NME2,GAPDH,API5,DBT,FZR1,CGAS,EEF1AKMT3,RCHY1,VAC14,TAB2,DNAJC2,COMTD1,TBK1,CCT5,OLA1,ARF4,RIGI,PSMA5,CSE1L,ABCE1,RPL3,IGF1R,IDH1 |
| 1.078e-05 | -11.44 | SYMPK (symplekin scaffold protein) | protein interactions | 8189 | 213 | 89 | 19454 | 5460 |
FKBP4,CPEB1,UBXN6,GSTM3,VPS26A,CACYBP,WIF1,MIR9-1,SUMO2,MIR214,SIN3A,MIR7-2,MTA2,SMARCB1,CYB5B,PDHA1,NUDCD3,CSTF2T,SAP30,TOP3B,SSRP1,RBBP7,KRAS,SEMA4C,MIR155,MIR363,DNAJB6,PSMD1,SNRPB,CPSF2,MYC,MIRLET7D,ESR2,RBBP4,MIRLET7B,S100A6,CPSF1,LMBR1L,NFKBIB,RAN,RFXANK,NPTN,NOP53,RP2,HSPA8,P4HA2,DCTN3,CXCR4,SNRPA,MIR34A,SNRNP70,CDC5L,RPL35A,MIRLET7G,PRNP,TOP1,MYBL2,MIR25,AIP,SSU72,EEF1AKMT3,MIR17,SIGLECL1,MIR200C,MIR16-2,TRIM63,MIR9-3,AR,SMARCA5,CSTF3,TENT2,VIRMA,UBE2I,MIR21,RPA2,RPRD1B,MIR1-2,CPSF4,CCND1,MBD3,MIR29A,MIR107,KDM1A,CLK1,MIRLET7I,RPA3,BAP1,SIRT7,PML |
| 1.078e-05 | -11.44 | SEC24A (SEC24 homolog A, COPII coat complex component) | protein interactions | 10802 | 213 | 89 | 19454 | 5460 |
YWHAH,XPO1,YWHAG,RAB5C,VPS26A,PDAP1,YWHAB,GJA1,IGBP1,EGLN3,NUP35,GFOD1,TTC9C,SNX2,TOP3B,B3GNT2,STIM1,STMN2,SLC39A7,EWSR1,TMT1A,TFG,AHCYL1,SAR1B,ARL5B,EPHA4,ROCK2,PSMD1,CUL3,NTRK3,YWHAZ,SEC61B,ARF1,S100A6,USP16,B4GALT3,OTULINL,PTAR1,BET1,PIH1D1,NUBP2,EP300,TTC1,LAMP3,SLC25A46,TSNAX,STYK1,KCNJ10,SMAD4,TRAPPC2L,DSTN,SEC23A,EPHB6,FAM118B,POLE3,TMPO,CAV1,CAND1,UBXN2B,TP53,TNRC6C,ILF2,FURIN,UBE2B,IGF1R,DDR1,RAB1A,SEC13,B4GALT1,OPTN,CCNF,CREB1,STUB1,ROCK1,VIRMA,ST7,FUT8,SEPHS2,STAT6,RPA2,SSR1,FGFR1,PRKCB,RAB9A,DERL1,ARFIP1,RPA3,SLC39A9,CSTB |
| 1.082e-05 | -11.43 | ZFAND2B (zinc finger AN1-type containing 2B) | protein interactions | 130617 | 41 | 25 | 19454 | 5460 |
ATG9A,PSMD3,CUL3,PSMD10,ASB7,H1-1,PSMC5,PSMD6,UBB,PSMC4,TANK,FAF2,TMC7,PAAF1,ZDHHC4,TMEM31,OR6M1,PSMC3,RHOU,GLUL,UBE3A,DERL1,SEM1,RBCK1,PSMD12 |
| 1.085e-05 | -11.43 | TCR signaling | REACTOME pathways | R-HSA-202403 | 119 | 60 | 10285 | 3229 |
PSMD1,PSMB2,PIK3CA,PSMA6,UBE2V1,PSMD12,UBE2N,PSMC1,TAB2,BCL10,CD4,RPS27A,PSMD4,PSMC3,GRAP2,PSMA1,PTPN22,PSMB9,SEM1,IKBKB,PSME2,UBE2D1,PSMD6,TRAF6,PAK2,PSMB4,PSMA2,FBXW11,ITK,PSMB6,PSMB3,CSK,CD247,NFKB1,PSMA4,PSMB11,PSMC5,PTEN,PSMB10,PSMA5,PSMB5,PSMA3,PSMC4,PSMD3,PIK3R2,PSMB7,CD3G,PIK3R1,PSMB1,UBA52,LCP2,UBB,PSMD14,PRKCQ,NCK1,PSMD7,NFKBIA,PSMD10,SKP1,PSME1 |
| 1.087e-05 | -11.43 | TET2 (tet methylcytosine dioxygenase 2) | protein interactions | 54790 | 131 | 60 | 19454 | 5460 |
TRIM21,SNIP1,HSPD1,PABPC1,MNAT1,TF,EGR2,SOX2,EEF1A1,SMAD1,TP53,PHC1,TBC1D4,BPIFB1,MYL12A,EGLN3,CDC5L,LANCL1,HSP90AB1,EIF2B2,VPS26C,YWHAG,YWHAH,TPM3,ZNF207,GAPDH,ELOC,PRDX1,LYZ,YWHAB,ECD,HSPA8,RNF113A,PML,MBD3,AZGP1,MYL6,CALML5,ALB,PSPC1,ARF1,TUBA1B,ENO1,VPS72,VIRMA,STAT5A,LDHA,ACTB,TUBB,HLF,NONO,AR,HNF1B,MYC,SUB1,CUL2,SFN,UBE2H,YWHAZ,PKNOX1 |
| 1.096e-05 | -11.42 | Host Interactions of HIV factors | REACTOME pathways | R-HSA-162909 | 134 | 66 | 10285 | 3229 |
NUP153,SEM1,PSMB9,NUP62,PSME2,PSMB4,PSMD6,PAK2,RPS27A,NUP35,PSMD4,PSMC3,AP1S2,PSMA1,SLC25A5,PSMC1,PSMD12,NUP37,CDK9,CD4,RAN,PSMB2,PSMD1,AP2M1,NUP42,NUP107,PSMA6,XPO1,AP2S1,HMGA1,PPIA,PSMD7,PSMD10,KPNA1,PSME1,ELMO1,SKP1,UBA52,AP1M1,RANBP1,UBB,PSMD14,ELOC,PSMA3,PSMB5,PSMC4,PSMB7,ARF1,APOBEC3G,PSMD3,NUP50,PSMB1,PSMA2,AP2A1,PSMB6,CD247,PSMB3,CD28,PSMA4,SLC25A4,BANF1,B2M,PSMB10,PSMA5,PSMB11,PSMC5 |
| 1.097e-05 | -11.42 | vacuolar membrane | cellular component | GO:0005774 | 490 | 186 | 19108 | 5553 |
BLOC1S2,CD63,PRCP,KLC2,PIP4P2,CYB561,SLC48A1,CMTM6,TMEM59,CHMP5,NDUFC2,AP5S1,SAR1B,EVA1A,MREG,NEU1,FLCN,SLC17A5,B2M,LDLR,SLC38A9,AP1S2,SH3GLB1,TMEM203,GLIPR1,ATP6V1A,CHMP1B,YWHAB,TLR8,OSTM1,ATRAID,VAC14,WDR11,GPR137,VTI1B,CHMP1A,BORCS8,MYO6,SESN2,CHMP4C,UBXN6,TMEM199,STOM,ATP6V1C1,ATP6V0E1,GNAQ,NAPG,SNAP29,TEX264,VAMP8,LAMP2,PLEKHF1,BORCS7,GABARAPL2,LAMTOR3,LITAF,RNF167,PSEN1,BST2,GNB4,RRAGA,RAB14,LAMP5,CTSD,ABHD6,STX7,SNX14,SLC11A2,CD164,MIOS,NCSTN,B4GALT1,MTMR2,RHEB,ENTPD4,VPS33A,RAB2A,RNF152,DPP4,CTSA,BORCS5,TM9SF1,MAP1LC3B,TAB2,TMEM106B,CYBRD1,TRIM23,TMBIM1,ATP6V0B,KICS2,GNA11,LRRC8A,TFEB,PLAAT3,TMEM165,TMEM45B,VAMP7,SEC13,TLR3,TRAF3IP3,FLOT1,ENPEP,BRI3,CLCN6,HPS6,VPS16,SYNGR1,ATP6V1G1,LMBRD1,LAMTOR1,TOM1,VPS18,SLC38A7,RAB37,PLD3,STX17,CHMP2B,TMEM30A,AP2M1,SPHK2,PCSK9,ATG16L1,CPNE1,TLR9,HSPA8,MMD,LAMP3,ACP2,RAP1B,ATP8A1,VPS39,GNB1,DRAM1,VPS4A,LAPTM4A,RAB5C,SLC2A8,ATG9A,ATP6AP2,CHMP2A,SNAPIN,MCOLN1,TLR7,LAMTOR2,TMEM74,CDIP1,FCMR,SLC22A17,CFTR,CD1B,VAMP1,CD1D,PIP4P1,SLC7A14,SLC35F6,BORCS6,AP5M1,TMEM179B,MINAR2,RB1CC1,KXD1,GABARAP,VMP1,EEF1A1,MITF,GABARAPL1,MARCHF9,DNAJC5,RRAGB,TFE3,TASL,ABCB9,UBA52,AP2S1,SURF4,RAB3D,ATP6V1D,THBD,STARD3NL,RNASEK,VLDLR,AP1M1,AP2A1,ATP6V1G2,GNAI3,MAP1LC3A |
| 1.103e-05 | -11.42 | VRK2 (VRK serine/threonine kinase 2) | protein interactions | 7444 | 216 | 90 | 19454 | 5460 |
DNAJC22,FTL,PXMP2,TACR3,STX7,RAB5A,OTULINL,RND2,SEC62,ESR2,LMBR1L,SEC61B,RMDN3,LMNB1,CCT2,ILK,NTRK3,FIS1,RAB11A,MYC,OST4,KRAS,TMT1A,RPL31,CYP2C9,TMEM88,COX8A,TMEM268,PTRH2,RAB4A,STIM1,RPN1,TMEM14B,RND3,DHX38,RAF1,DNAJC25,FAF2,TCP1,RHOH,NUP35,NTMT1,KCNA2,RAB35,SPINT2,GJA1,RHOG,RAB5C,MARCHF5,ATG9A,LAMP2,DDRGK1,RAB9A,DERL1,CYP2C18,SSR1,LMNA,CHRNB2,SF3A1,ST7,CDC42,RHOJ,SEC63,CIB2,SLC1A1,CIAO1,CSK,RAB3B,TOLLIP,SRPRB,FKBP8,TSPAN17,TP53,CCDC47,TMEM205,MGARP,DNAJC1,TMED9,MARCHF4,ARF6,LMAN1,DUOXA2,TMPO,PTPN1,RAC2,HSD17B11,FAM187B,ESYT1,SLC25A46,LAMP3 |
| 1.110e-05 | -11.41 | UGDH (UDP-glucose 6-dehydrogenase) | protein interactions | 7358 | 96 | 47 | 19454 | 5460 |
HSPB1,TRAPPC4,FAM174A,ATG7,LCN6,LAMP3,SNX1,AK5,EGLN3,TMPO,DUSP6,ARL10,NUDT9,XPO5,EZH2,OTULIN,RAF1,UBE2V1,ISG15,TRIM37,TNF,RIGI,PDIA6,FAS,ATP1A1,CIAO1,MYC,MAT2A,GORASP2,GGH,BAG3,UGT1A1,ESR2,MAT2B,CTTN,CCNF,OPTN,GTF2A1,RNF7,RPA2,LAP3,CFTR,CDC42,STAU1,UGDH,INPPL1,RPA3 |
| 1.123e-05 | -11.40 | B4GALT3 (beta-1,4-galactosyltransferase 3) | protein interactions | 8703 | 104 | 50 | 19454 | 5460 |
OS9,HSP90AB1,ATP5PD,DNAJB9,EED,NRSN1,ADAM21,ATP5MG,ERLEC1,SLC39A7,HSPD1,TRAPPC13,SFTPC,EZH2,TMEM205,CBLN4,TMEM59,ATP5PB,ANP32A,B4GAT1,REEP4,ATP5F1B,PTEN,B4GALT1,DNASE1L1,SURF2,ARF1,CGRRF1,ATP5MC1,ATP5F1A,KDSR,RSPH1,ZDHHC17,CLEC12B,LPAR1,EP300,SAT1,ATP5IF1,SYVN1,SLC39A9,ARL15,FAM8A1,UBE2M,GHITM,GOLGA5,CTBP1,CCL3,KLRD1,TMEM106A,SLC19A2 |
| 1.123e-05 | -11.40 | USP39 (ubiquitin specific peptidase 39) | protein interactions | 10713 | 193 | 82 | 19454 | 5460 |
PRPF31,RUNX1,H2BC9,SNRPB,MYC,HNRNPC,SP1,UBE2H,RIT1,SNRPD2,PTEN,ARF1,SF3B6,CMTR1,NFKBIA,GGPS1,SNRPB2,ESR2,SRPK2,STAT1,SNRNP40,FBXO22,SNRNP27,TXNL4A,SF3A1,RPA2,TRIM5,SF3B1,BAP1,SNRPA,RPA3,SIRT7,PRPF4,LSM8,FXR2,STAU1,DDRGK1,CTNNB1,PRPF19,IFI16,TRIM8,ID1,BRD3,DDX23,SNRNP70,TRAF6,TSR2,SRSF1,PHB1,RBM42,SRSF10,CDC5L,CETN2,FZR1,CAND1,KCTD10,TOP1,NCSTN,CD2BP2,TPBG,CSNK1E,DHX38,TP53,ZRANB2,SNRPE,APEH,NUPR1,SART3,EZH2,ACVR1,RAB27A,PCNA,HAPSTR1,RUVBL2,SRSF7,DHX9,MEPCE,SSRP1,KRAS,LSM4,H3C1,TRIM26 |
| 1.124e-05 | -11.40 | EEF1A2 (eukaryotic translation elongation factor 1 alpha 2) | protein interactions | 1917 | 260 | 105 | 19454 | 5460 |
PBDC1,GJA1,CACYBP,HNRNPL,SUMO2,HSPB8,YWHAH,UBXN6,WWP2,SLC38A7,MGMT,RHOG,AGR2,FKBP4,SREK1IP1,UBE3A,PABPC1,RNF26,HNRNPF,DCP2,ISG15,NCSTN,LGR4,GTF2E2,EEF2,CKS1B,RAF1,E2F4,RPS11,EZH2,CHMP4C,FAM177A1,RAN,ACTB,PSMD1,MYC,CUL2,CUL3,PSMD14,NMRAL1,PSMA3,MIA2,EIF1B,GPM6A,EEF1G,PITHD1,MTF1,SLC25A3,PPT1,CEBPG,EEF1B2,CD274,RPL12,OR4D2,CDK9,DCUN1D1,CAND1,RPL35A,COPS5,CD81,HDAC6,SLC13A5,GMPPB,TUBG1,MAP1B,RAB1A,SOCS2,FBXO25,MEPCE,SMN1,SEM1,NEDD8,TF,MLLT6,EEF1A1,RPSA,TFCP2,CAB39,PTEN,CCNF,CHRM4,HOMER1,VIRMA,KCTD9,RUNX1,GORASP2,USP14,CARS1,CDC73,STK11,UBE2H,PKNOX1,BAP1,RPA3,RPL4,SNRNP27,CDK7,TPT1,UBE2M,HEXIM1,HAUS2,ZMYM6,RPA2,METTL14,WWP1 |
| 1.128e-05 | -11.39 | RNA Polymerase II Transcription Termination | REACTOME pathways | R-HSA-73856 | 71 | 40 | 10285 | 3229 |
CASC3,MIR636,DHX38,SRSF7,SRSF2,EIF4A3,DDX39A,ALYREF,SRSF1,CDC40,ZNF473,LSM10,MAGOH,THOC6,THOC1,CSTF2T,MIR1234,CPSF4,ZC3H11A,SRSF4,CLP1,CPSF2,SLU7,THOC3,POLDIP3,CSTF3,MIR939,DDX39B,SNRPD3,PAPOLA,NCBP2,UPF3B,MAGOHB,CHTOP,THOC2,SNRPG,CPSF1,SNRPE,FYTTD1,SNRPB |
| 1.128e-05 | -11.39 | Cleavage of Growing Transcript in the Termination Region | REACTOME pathways | R-HSA-109688 | 71 | 40 | 10285 | 3229 |
MIR1234,CSTF2T,THOC1,CPSF4,LSM10,ZNF473,THOC6,MAGOH,SRSF4,CLP1,CPSF2,ZC3H11A,SRSF2,SRSF7,MIR636,CASC3,DHX38,SRSF1,ALYREF,CDC40,DDX39A,EIF4A3,SNRPG,SNRPE,SNRPB,FYTTD1,CPSF1,DDX39B,MIR939,PAPOLA,NCBP2,SNRPD3,SLU7,CSTF3,POLDIP3,THOC3,MAGOHB,THOC2,CHTOP,UPF3B |
| 1.142e-05 | -11.38 | SLTM (SAFB like transcription modulator) | protein interactions | 79811 | 145 | 65 | 19454 | 5460 |
LTBR,RIGI,DPM2,SSRP1,MRPS33,ERLEC1,IKZF5,APOBEC3D,SOX2,E2F4,ZNF263,TMEM14B,CHMP4C,DMAP1,SKA3,EZH2,EED,CEP19,CDK9,PTP4A3,TOP1,HNRNPA1,IFI16,MAP4,ANKRD50,UQCR11,AGR2,SNRNP70,DDX23,CCDC65,EP300,EXOSC4,HSPA8,SIRT7,PML,SNRPA,RPL27,RPA3,AATF,HMGB1,PSENEN,ATG16L1,PABPC5,GHITM,RPA2,FGFBP1,EZH1,TACO1,ESR2,SRPK2,MIRLET7D,GGPS1,POLR2B,IFI6,SPCS1,MBL2,TAX1BP1,JAKMIP2,MATR3,ANAPC15,MYC,DNAJC19,PEA15,CHCHD4,LMNB1 |
| 1.144e-05 | -11.38 | TRIP13 (thyroid hormone receptor interactor 13) | protein interactions | 9319 | 266 | 107 | 19454 | 5460 |
UBE2I,SGTA,ZNF655,CCNF,OPTN,FBLN5,CDC20,DDAH2,VIRMA,ARMC6,NTAQ1,USP14,MGAT5B,RAB2A,IL2RB,UBE2H,NIF3L1,PRKCB,RAB9A,SQSTM1,RPA3,BAP1,CRYZ,NME4,FBXW7,TPT1,PAX9,STAMBP,RPA2,SDCBP,TES,HDHD3,PTPN1,EEF2KMT,COMT,SPMIP9,ALYREF,CDC5L,ARF6,PLSCR3,POLR3GL,ANKRD10,MPPED2,H2AC4,HAPSTR1,MAP1B,MEPCE,FBXO25,MDC1,CRYBA2,TTC4,MAP1LC3B,CLEC2B,METTL15,FBXO8,PCMTD2,MAD2L1BP,TNFRSF9,LMBR1L,MIDEAS,MTG1,MAD2L1,MAD2L2,MYC,CUL3,PBLD,RAB11A,CRMP1,COP1,LAMTOR1,AKAP1,DCTN3,ACTMAP,COIL,G3BP2,HSCB,BET1,PRR13,PLSCR4,PIH1D1,KRT8,ARL11,FOLR1,PHB1,POLR2L,LRRC61,EGLN3,HNRNPL,SMUG1,SUMO2,AASDHPPT,DDRGK1,PLAC8,SIGLEC5,CBL,POU5F1,STAMBPL1,PEX3,KRTAP12-4,FLOT1,LASP1,PELI1,G3BP1,NCSTN,MSX2,VDR,PARP11 |
| 1.148e-05 | -11.38 | NSDHL (NAD(P) dependent steroid dehydrogenase-like) | protein interactions | 50814 | 159 | 70 | 19454 | 5460 |
LMAN1,TMPO,RPL35A,GJA1,HSD17B11,RAC2,LDLR,PTPN1,RAB35,COMT,TMEM30A,RHOG,AGR2,ESYT1,LAMP3,CSNK2A1,MOV10,LAMP2,RAB5C,MARCHF5,ADIPOR2,AKAP12,KRAS,RAB3B,ERG28,EMC2,CYP2C9,TMT1A,CCR1,STIM1,RPN1,TMEM31,RAB4A,APOO,DNAJC25,RAF1,MVD,DCAKD,COPE,TENT5C,TAX1BP1,RHOJ,RMDN3,SEC61B,CYB5R3,RHOB,LMNB1,CYP1A1,RAB11A,STX7,HSCB,SLC31A1,EMC1,SYVN1,HSPA8,EP300,RAB9A,DERL1,RPA3,PEBP1,TMX2,VAPB,RPA2,SSR1,GPR35,RND2,OTULINL,SEC62,CDC42,ST7 |
| 1.148e-05 | -11.38 | EPB41L1 (erythrocyte membrane protein band 4.1 like 1) | protein interactions | 2036 | 159 | 70 | 19454 | 5460 |
CAV1,DIRAS3,LMAN1,RHOH,SNRPD3,PRNP,ARF6,HNRNPL,SPPL3,COPS2,RAC2,GJA1,ARMC1,PSMB5,PSMB4,HRAS,RAB35,YWHAB,HSPB1,HAX1,NOS1AP,RHOG,COPS5,YWHAG,YWHAH,ZCCHC10,FLOT1,COPS4,SCML1,KRAS,PSMA5,STARD13,ISG20,ATP5PB,DDAH2,SRPK2,VIRMA,RHOJ,MED17,POP7,CHRM5,GRIA1,YWHAZ,RHOB,AGAP2,DNAJC5,PSMA4,NOP16,RAB11A,COPS7A,RAB2A,CXXC1,STX7,SAP18,POLA2,GPM6A,KRT222,MTDH,NUP50,RHOU,INPPL1,ACACA,DRD3,SDC2,PSMB7,CDC42,RND2,ARHGAP1,PSMB3,WDR77 |
| 1.158e-05 | -11.37 | EXOC7 (exocyst complex component 7) | protein interactions | 23265 | 123 | 57 | 19454 | 5460 |
SEMA4C,RIGI,STX11,POC1B,EFNB1,DISC1,SIGLECL1,IFT57,EXOC3,CA14,HGS,IL1R2,DLG3,TBK1,COMTD1,SNAPIN,PLEKHF2,CDC5L,EGLN3,CD274,H2AC4,EXOC2,RIOX2,PRPF19,KXD1,MOV10,EXOC1,INSYN1,NPTN,KDM1A,BAP1,CXCR4,CD40,RAMAC,ZC3H14,NUP62,CFTR,RALA,TRIM54,APEX1,ESR2,LMBR1L,SCN2B,CCNF,S100A6,PKNOX1,YAE1,EXOC8,CDC73,CCHCR1,RAB11A,GPR17,CUL3,DSN1,CCDC85B,EXOC5,SMARCE1 |
| 1.159e-05 | -11.37 | INSIG2 (insulin induced gene 2) | protein interactions | 51141 | 176 | 76 | 19454 | 5460 |
PSMB3,SLC16A10,ELFN2,JUP,PSMB7,LMNA,ARCN1,CD40,TMX2,HSPA8,PHB2,RNF5,CMAS,HSPA5,SCN3B,PSMA4,ATP5F1A,H2AZ2,PSMD14,ELOVL4,ENO1,VDAC2,RPS3,UQCRC2,RPS12,CYBC1,PRMT5,RMDN3,PSMC5,CAB39,ADRM1,MATR3,PSMD4,COPE,MTCH2,RANBP1,CSNK1E,DDX39A,EEF1A1,FAF2,ACTN4,STIM1,RPN1,TFRC,PLS3,PSMC3,ABHD4,TMEM14B,HNRNPA2B1,LSM14A,SLC25A11,HSPD1,TRIM21,ATP6V0B,GPR37L1,RUVBL1,HNRNPK,PSMA2,PSMD12,PRDX1,GAPDH,TPM3,HNRNPA1,PPM1B,AQP2,RNF139,ALYREF,PSMB1,SEC23A,KRT8,TRMT10B,CAND1,AFTPH,HSP90AB1,TMEM237,TMEM45B |
| 1.162e-05 | -11.36 | Proteasome_bsu_CS | interpro domains | IPR016050 | 12 | 11 | 18521 | 5414 |
PSMB6,PSMB4,PSMB3,PSMB5,PSMB10,PSMA4,PSMB9,PSMB2,PSMB11,PSMB1,PSMB7 |
| 1.165e-05 | -11.36 | positive regulation of cell activation | biological process | GO:0050867 | 381 | 151 | 18204 | 5365 |
CD4,MIR30B,MIR21,PLPP6,CD81,LILRB4,CD46,LILRA2,ZBTB16,PRKCQ,TACR1,MYD88,IL4,TLR9,SMARCD3,RUNX1,SOCS5,IL7,MEF2C,EXOSC3,CHRNB2,IL23A,BLOC1S3,CBFB,CD80,B2M,CD28,WNT10B,SMARCB1,MAD2L2,EPO,TICAM1,TYROBP,IL15,CAV1,HMCES,NECTIN2,PELI1,SMARCE1,THY1,KLHL25,TLR4,LEP,CD40LG,BTN2A2,IL6ST,PTPN11,BCL10,HSPD1,CD274,FOXP3,IL12A,SRC,DHPS,LILRB1,ACTL6A,NKAP,SASH3,MIF,PNP,IL18,CCL3,CD83,CD86,IL13,MIR142,GP9,IL6,IL21,CSK,CLEC7A,IL12B,SLC7A1,MMP14,IFNG,CTSC,ACTL6B,PIK3CA,CD47,CCL5,CYRIB,PDCD1LG2,RHOH,DPP4,CCL19,AIF1,EFNB1,MIR130A,TGFBR2,IL2,CCR2,TRAF6,NLRP3,CD38,TNFSF13,XBP1,CCL21,BAD,IL15RA,RAG1,SPHK2,CDKN1A,TIRAP,IL5,ICOS,IL2RA,TNFRSF14,JAK2,CCL2,AGER,PYCARD,STAP1,CD226,DUSP10,STAT6,TLR6,CCR7,AKT1,BCL6,CD40,IL1B,SYK,CD1D,HMGB1,PPP3CA,IL2RG,TFRC,YES1,TOX,SELENOK,NCK1,RPS3,FGF10,GPAM,TESPA1,KMT5B,MIR145,SHLD1,IL1A,SLC39A10,IL10,XCL1,KARS1,CD2,IGF1,EP300,ACTB,CD209,TNF,ACTA2,VSIR |
| 1.168e-05 | -11.36 | MDH1 (malate dehydrogenase 1) | protein interactions | 4190 | 134 | 61 | 19454 | 5460 |
RPS28,PML,CSTB,RPA3,INPPL1,BAP1,PMAIP1,PRDX6,HSPB2,NMRAL1,GPC1,OXCT1,EMC1,UBA52,SPR,LAP3,CDC42,RPA2,LMNA,LDHAL6B,PIH1D1,UBE2M,NFKBIA,TRIM24,CMBL,TENT5C,LDHA,LDHB,AKT1,ACO2,HMGCS1,CUTA,MTPN,BRCA1,LMNB1,UBE2H,HTRA2,MDH1,HSP90AA1,OAT,EMC2,HSD17B10,REXO2,ABHD10,SAR1B,TP53,RAF1,MSX2,PGM1,SOX2,NHERF1,SOD2,CD274,FABP5,GATD3,HSP90AB1,GLRX,ESD,AGR2,GSTO1,YWHAB |
| 1.171e-05 | -11.35 | RINT1 (RAD50 interactor 1) | protein interactions | 60561 | 225 | 93 | 19454 | 5460 |
CCR6,ZNF688,SSX2IP,CDR2L,EEF1AKMT3,CD274,PTPN1,RB1,RAC2,HSD17B11,DNAJC1,TMPO,STX6,MAP1LC3B,SIGLECL1,TAF2,GRAP2,RBM41,STX18,VAMP5,CCHCR1,NAPA,CTNNA1,CHRM4,VAMP3,ZNF655,GNAI2,SEC63,FAM161A,SEC22B,ATG16L1,SPTBN1,ST7,USE1,SSR1,RPA2,SCLT1,PML,RPA3,SNAPC1,DERL1,SYVN1,PIK3R2,SGF29,BNIP3L,MBD3,GAS8,P2RY10,SKIC8,RHOG,VPS4A,NAB2,CEP57L1,OPRL1,PRPF18,RNF39,DNAJC25,STIM1,HGS,SMARCB1,TMT1A,XPNPEP1,ZBTB16,FANCG,OPRM1,GPR17,LMO2,SMARCE1,BTF3,PRPF31,FAS,TSEN54,SCFD1,EXOC8,FAM107A,SCNM1,TACO1,LMBR1L,S1PR4,SEC61B,FCHSD2,APLNR,BET1,PGRMC1,FAM234A,BORCS6,OTULINL,SEC62,RAB5A,RAMAC,MYOZ3,NFIL3,NPTN |
| 1.171e-05 | -11.35 | protein K11-linked ubiquitination | biological process | GO:0070979 | 31 | 21 | 18204 | 5365 |
UBE2H,UBE2W,UBE2E3,CDC26,ANAPC13,ANAPC11,UBE2B,CDC16,UBE2E2,CDC23,ANAPC2,AREL1,ANAPC4,UBE2L3,UBE2A,UBE2D3,UBE2S,TRIM26,RNF26,RNF115,FZR1 |
| 1.173e-05 | -11.35 | cell activation | biological process | GO:0001775 | 725 | 266 | 18204 | 5365 |
HMGB1,TOP2B,SYK,CLU,CD1D,BCL6,CD40,ITGB8,PKNOX1,FCGR2B,PYCARD,AGER,STK11,BATF,ACTB,CD2,SLC7A11,TNF,LMBR1L,SMAD3,CX3CL1,RBPJ,IL10,TESPA1,TUSC2,GPAM,CX3CR1,MRGPRX2,VAMP7,PDIA3,SELENOK,CSRP1,CMTM7,PHB1,SNAP23,GJA1,CD2AP,CD38,TRAF6,TLR2,CD1C,CEBPG,DPP4,F2,IRF4,CCL19,AIF1,NHEJ1,PLSCR1,RHOH,VAMP2,IL2RA,CXCL10,ILK,IL15RA,MYL12A,KCNJ8,RAG1,TBC1D10C,GPR89A,SLC25A5,PRDX1,NKAP,P2RY1,IL18,PRDX2,SRC,PHB2,MICB,DCLRE1C,FGL2,PIK3CG,CDK6,LRRC8A,CD40LG,LEP,TLR4,MDM2,CXCL8,PIK3CA,ICAM1,IDO1,IFNG,TCIM,TP53,P2RY12,CLEC7A,IL21,AZI2,LEPR,SLC39A7,CAMP,IL13,TPD52,PIK3R1,HELLS,PIK3R2,CD3G,IRF1,TNFAIP8L2,SLA2,PRKCQ,C1GALT1C1,LIPA,JAML,PTGER4,CD247,NBN,TLR1,IL15,SLC6A4,PTGDS,FBXO7,TICAM1,MIR181C,EGR1,GAPT,KDELR1,IL23A,FZD6,B2M,NCSTN,ITK,IL7,EZH2,CHRNB2,EXOSC3,UBASH3B,RAP2B,WNT7A,PPP3CA,COL3A1,PTPN22,AKAP17A,VAMP8,IL1B,RABL3,IFNA13,CCR6,PRMT5,NCR3,PDIA2,CCR7,TLR6,RNF8,STAT6,TNFSF18,RPL22,SLAMF9,SMAD4,EP300,IGF1,NOTCH2,PIK3R3,KARS1,METAP1,CTNNB1,HYAL2,RAB29,BAK1,NPR2,TMEM106A,NCK1,TOX,IL2RG,CCND3,TOLLIP,CCL21,CBL,NDFIP1,KIT,IFI35,IL2,TGFBR2,HBB,LTBR,EFNB1,MSH6,DNAJB9,TMEM229B,DLG1,IGBP1,MSN,LAT2,STXBP1,CD151,FKBP1A,JAK2,BST2,SKAP2,SYVN1,FOSL2,IRF8,CHGA,HDAC5,PRKCE,PRKCB,CPLX2,LCP1,RAB27A,CD79B,SASH3,CCL3,CD83,FOXP3,HSPD1,LILRB1,CSF2,NFIL3,IFNGR1,PELI1,TNFSF8,FOXP1,STOML2,CCL5,ITM2A,AKAP12,TLR3,KPNA1,FCER1G,TREML1,IL12B,BAX,TRAF3IP2,RSAD2,IL6,IFNA10,PPIA,CD86,HSPB1,IFNK,PLCB1,TLR9,IL20RB,EMP2,PSMB10,MYD88,PSMB11,IL4,RGCC,JAK1,ALKBH5,LILRA2,LCP2,PDP2,CD9,IFNA2,CD4,VWF,CD81,PSEN1,IFNB1,TYROBP,SOCS3,VAV2,RC3H2,NMI,WNT10B,FKBP1B,BLOC1S3,SWAP70,CD28,CD80,CBFB,MEF2C,ST3GAL1 |
| 1.177e-05 | -11.35 | oxidative phosphorylation | biological process | GO:0006119 | 105 | 52 | 18204 | 5365 |
COX4I1,ATP5PO,UQCRQ,FXN,SDHB,COX7A1,COX6C,NDUFB8,SLC25A51,NDUFA2,SDHC,NDUFC2,COX7B2,ATP5PF,NDUFS6,NDUFA4,COX8A,TAFAZZIN,NDUFB5,ATP5F1D,NDUFS3,ATP5F1E,UQCRC2,NDUFB4,COX6B2,COX5A,CYC1,NDUFB7,NDUFA5,NDUFA12,SDHAF2,UQCR11,ATP5F1A,NDUFB10,NDUFAB1,NDUFS8,NDUFA1,ATP5F1B,NDUFV2,NDUFB6,ATP5PD,UQCRC1,COX6B1,UQCC3,ATP5PB,STOML2,COX7B,ATP5MG,UQCRH,COX4I2,NDUFS2,COX6A2 |
| 1.183e-05 | -11.35 | SM | prosite domains | PS52002 | 28 | 19 | 12186 | 3388 |
LSM6,LSM4,GEMIN7,LSM14B,SNRPD1,LSM8,LSM3,SNRPD2,LSM2,SNRPE,LSM5,SNRPG,SNRPN,LSM14A,SNRPB,LSM10,LSM12,EDC3,SNRPD3 |
| 1.183e-05 | -11.35 | GNB2 (G protein subunit beta 2) | protein interactions | 2783 | 482 | 178 | 19454 | 5460 |
STK3,CACYBP,ATXN10,PHB1,RPL9,RPL23,NDC80,RFC2,G3BP1,LAMB2,GADD45A,HSPD1,RPS11,EZH2,GNG3,ACTN4,HSDL2,RAF1,GNB1,PRDX2,RPS9,SERINC1,CYB5R3,PELO,GNG12,PFDN6,PFDN4,PFDN2,NTRK3,RNF40,PYCR1,PYGB,PMAIP1,NMRAL1,TXNL1,ANXA7,SLC25A3,MYL6,CDKN1A,LEAP2,ASNSD1,CDK9,FAM118B,CGAS,ADAM21,LRRC40,HDAC6,RIGI,TTC4,PC,RGS6,GNG5,SLC25A10,STX8,MLLT11,DMAP1,GNG10,SLC29A1,CCT5,TBK1,RPL22,GNAI2,LDHA,CCNF,HERC4,EPHA2,PPTC7,AR,HMOX2,PPP1CC,TUFM,ATP5F1A,CIAO1,MEF2A,SMC4,PDHB,BORCS8,PDCL,GNG7,JUP,ATG16L1,RPS14,PCK2,COX14,CCT7,HSP90AB1,TCP1,TTC9C,NOB1,CPLX3,CBL,REG1B,ASB7,AGR2,FKBP4,XPO1,PFDN5,PFDN1,RPS4X,VDAC1,KRAS,PDIA6,RTCB,CCT8,GNA11,CSTPP1,GNAQ,SLC4A8,TUBB4B,TPPP,RPS7,CBLN4,NUDCD3,GNG13,APEX1,ESR2,RPL10,PPP5C,POLR2B,STAT1,FBXL14,VDAC2,CDKL2,COP1,SPCS3,CCT2,PCCB,TBC1D1,BTF3,LDHB,MYC,ADRB2,GNGT2,HDAC5,HSPA8,CSNK1A1,RPL27A,CAND1,COMT,AIP,SNRNP70,MED29,TUBG1,GAPDH,CD81,GNG2,RPL17,PDRG1,TMEM33,KPNA2,RPL3,BHLHE40,GNAI3,FURIN,NUPR1,TFCP2,FMO2,TP53,TXNDC12,STAT5A,PSMC5,SEC61A1,UQCRC2,RPS3,OAT,SPOP,ARL6IP6,CEP85,RPL7A,SLC25A1,HSPA5,CLU,MARS1,RNF113A,NLE1,UGDH,ACACA,CFTR |
| 1.185e-05 | -11.34 | Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1) | protein interactions | 26926 | 14 | 12 | 19454 | 5460 |
STOML2,COX6B1,CHCHD4,AK2,CHCHD6,PHB1,CCNF,CLU,CHCHD3,HMGB1,VDAC1,PHB2 |
| 1.187e-05 | -11.34 | TNPO1 (transportin 1) | protein interactions | 3842 | 284 | 113 | 19454 | 5460 |
CD274,EEF1B2,ALYREF,CD4,LDLR,PRNP,CDC5L,MOV10,COPS5,TMA16,USP15,NOSIP,MAP1B,TCEA2,RPL23A,HAPSTR1,IGF1R,KPNA2,THRAP3,VPS16,COMTD1,RRM1,IPO8,SIGLECL1,CCNF,ZNF330,TUBA1B,PHAX,PTPMT1,UBE2I,MACROH2A1,NDN,VIRMA,RALB,SMARCA5,VAMP5,KPNA6,AR,TMEM255A,ZBTB38,KCNJ2,RPA3,MME,UGDH,BAP1,SIRT7,SQSTM1,FTH1,DCTN4,RPA2,WRAP53,STOM,RPL26L1,SIN3A,COPS2,EGLN3,HMG20A,FAM174A,ATG7,HNRNPA1,NT5C2,DDRGK1,HNRNPD,PEX3,PPP3CA,HNRNPA2B1,RUVBL2,EWSR1,EFNB1,RBBP7,G3BP1,KRAS,RUVBL1,SAR1B,AHCYL1,RANBP1,TXNRD1,SOX2,NUP153,TUBA1A,TNPO2,RPS7,CA14,EZH2,TUBB4B,MTA2,MOB3C,LMBR1L,RAN,RANBP6,RBBP4,IREB2,TNPO3,ACO2,MYC,CUL3,BRCA1,CD40,SNRPA,MACIR,HDAC5,NUP50,YAF2,EP300,HADHA,HNRNPA0,NPTN,EEF1G,STAU1,RP2,COIL,FAM234A,CSNK1A1 |
| 1.190e-05 | -11.34 | DDX42 (DEAD-box helicase 42) | protein interactions | 11325 | 199 | 84 | 19454 | 5460 |
RIT1,RCL1,BRCA1,RPS6KA4,MECP2,SPOP,RBM15B,SNRPB,AR,NONO,DNAJC8,ARHGAP21,MYC,SNRPB2,PPP1R10,LRIF1,SNRPD2,SF3B4,CTTN,PSPC1,TACO1,SF3B6,CPSF1,CCNF,NUFIP2,MFAP1,HEXIM1,TOX4,RPA2,LMNA,ATG16L1,SF3A1,FBXW7,EP300,NUP50,PRKCB,SF3B1,SIRT7,PML,SNRPA,BAP1,RPA3,TIAM1,DDX23,COPS5,PPIL4,RBM17,NDC80,PRPF19,MOV10,CDC5L,DHX15,CDK9,MDM2,TOP1,EED,WDR82,SYNCRIP,SRP14,SNRPE,TAF2,NUPR1,SF3B5,DISC1,CBX3,EXOSC8,FOXJ3,ISG15,CD2BP2,RPSA,CSNK1E,SSRP1,FBXO25,MEPCE,RUVBL1,KRAS,SEM1,PDIA6,UBE3A,RPL23A,FAM76B,RUVBL2,SNIP1,NOSIP |
| 1.196e-05 | -11.33 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5198 | 1609 | 16828 | 4835 |
PPM1G,FLRT2,TAF5L,E2F4,CD1D,TOPBP1,CDH8,G2E3,TRIM11,PROM1,PCGF3,MAX,TCEAL7,RHOB,CAB39,KLK5,DDX4,GNAI2,GRIA2,PEX5L,TOP3B,SLC43A2,CBX5,RAB1B,RGS5,SNIP1,UBE2D1,LDHAL6B,TNFRSF14,RBMX2,GSTK1,PPFIA3,CLIC2,NLRP1,STX18,FBP1,SLITRK2,CDKN1A,RP2,FOXN2,KDSR,DNAJC27,STARD13,CRKL,SOS2,PHKA1,FBXO25,SCYL2,RAB37,DET1,WEE2,RNF14,PCDH19,RAB5C,PNP,STK38,PRRG1,DNAJC10,RAF1,SMAD3,RAP2C,PPP2R1A,DDX5,EIF4A3,IL6ST,CYTH1,UBE2F,FOXP2,TIMP1,RAB9B,INPP4A,FKBP10,EZH2,LAMTOR3,STAT6,SNX24,GPSM3,ISG15,TP53INP2,STK11,DYRK1B,TESK2,FN3KRP,WIF1,RPS27L,WDR44,MEF2C,CTNNA1,RAB2A,CCNF,LITAF,ARL4A,RPRM,FUT1,FANCG,PAX6,STAT1,ZNF507,TLR6,RPN1,PPID,RFTN2,MSX1,RAB14,RIOK2,RPL26,POMP,SDC4,DYRK2,FOS,OR4N4,EGLN3,DYNLT3,TMEM31,SCD5,F10,MAFG,NEK2,NFKB1,PC,PRKAG1,RAB5A,APOBEC3D,HNRNPK,UTP23,RNASEL,RNF26,RAB13,CDK5,GNG3,RAB33A,TOB2,RNF167,TNFSF18,DNAJC8,RAB23,PPFIBP1,PTGER1,SLC45A3,SUMO3,OPHN1,OGG1,CCR3,PKIG,JUN,ADCY2,RHOJ,CBLN4,WWP1,TMEM164,APLN,PHB2,MMADHC,NR1H2,NUS1,PLEKHA8,CDSN,YWHAB,PPP1CB,NFYB,RABL3,UPF3B,ZCCHC12,ARRDC3,KLHL15,DAPK1,SESN2,BNIP3L,RERG,CXCL14,ADAMTS1,RRAS2,PPP1R16A,COPS7A,RNF20,DDX42,NUP153,OTUD6A,HDAC6,PBLD,RNF39,ANAPC13,PAFAH1B2,NPY5R,HSPA14,CXCR4,LCN9,PGR,RAN,USP14,TSC22D3,RBM12,GNA14,CXCR6,ZMYM4,BTG1,SERPINA5,BICD2,ASB3,RNF122,FAM162A,CCNB1,AKAP14,CHRDL1,NLRP6,METTL2A,PTGER4,TRAF3IP2,UHMK1,IZUMO1,ERH,PIP5K1A,PIK3R3,MAP3K11,GTF2H2,MORC4,TERT,GNG2,RASL10A,IDH1,GNG13,SAT1,CD2AP,SRC,ICAM3,RAB3D,RUVBL1,GIT2,NKIRAS1,KDM4B,RAB33B,CDC42EP3,MCM3,RCE1,TRIM54,MGAT1,RASGRP3,RGS19,PDCD4,LDOC1,CREBBP,ARHGAP25,HTR5A,DNAJC22,BCL7B,SERPINI1,IDO1,PPM1D,CXCL12,FLCN,F9,PGPEP1,OPRK1,TNFSF13,TOP1,APOO,TMC7,SNX17,GNG5,DSTYK,CCR2,HMG20A,IPO8,HSP90AB1,POLE4,GPHN,SFRP4,CSRNP1,ATG4A,PADI2,SYP,FUNDC2,SMC4,RAB22A,UBE2V2,AK5,ITGA6,CSNK1A1,UBE2M,PIR,TRIM10,TFE3,UBE2E3,PREPL,MOSPD1,RNF113A,EFNB1,FCHSD2,TSPO2,NUP37,LRRC1,TRIM5,EIF4E,TM9SF4,COX4I2,CDKN2C,ITGAV,MXI1,USP5,FERD3L,FOXP4,RNF126,LDHB,DDX39A,IGBP1,AKAP12,SMARCA5,DRAM1,BAK1,ELK4,FAIM,CD274,PPP2R3A,FZR1,SMAD4,SLC1A3,ACSL4,TRIM24,CIB2,EED,LGR4,ABHD14B,HSCB,TFEB,PPP1R12A,VMP1,HSPA8,SSRP1,LMNB1,BECN1,MED21,DNTT,OSBP,GOLGA5,ZBTB2,KLK6,DNAJC3,SERINC3,TSN,STAU1,PLA2G12A,PCDHB1,BRCA1,TRAF2,RAB30,GABRA2,NPR2,CDK4,PFDN4,RGS2,DUSP19,NME1,PPP4C,PDHA1,NOS1AP,BCL10,KCNMA1,DNAJB2,CD1A,CEP97,FOLR2,PDRG1,PTPN22,SOCS3,PGAM1,RNF121,LRP6,STK24,NFKBIB,MMP21,RAC2,PRKAB1,GNB4,CNTN1,ACTB,PAX9,PCMTD2,CSNK1A1L,SOX2,LNX2,SNX18,TYW3,RFC2,DERL1,CYP4F12,ARHGEF6,RABL2B,FAM199X,NELL2,HEY2,RBM17,ZDHHC14,ADRB1,FRMD8,USP2,CAMK1,SNX2,ARFIP1,SIX5,TRIM21,ARMCX2,RMND5B,NOVA1,MCAT,SEC63,RBBP7,HECW1,TRIM37,PTTG1,PTPN1,BCCIP,AGER,RAB18,NEUROD6,IDH2,FKBP14,INSM2,RAB31,ARMCX5,DYRK1A,DRP2,AGK,ANAPC2,FBXO32,TRIM27,COPS2,C1GALT1C1,LGI3,EIF2AK2,UBAC2,PPP3CA,NME2,CD200R1,FGFR1,SHC1,SCFD1,SATB1,CIB3,ACO1,RALGAPA2,CAMK2G,PCK2,SRP54,KLRD1,DNAJC5,MSRB3,JUP,EXT1,VRK1,PGK1,MMP9,BUB3,CFL2,S100A6,SNX5,OR4N5,ZMYM2,RS1,KIT,CYP3A5,LMNA,PHF1,AFTPH,PLP1,DCAKD,RNF41,TMEM74,GNG7,CTNNBIP1,KPNA1,CSNK2A1,GRAP,RAB3B,DEFB116,MLF1,ZBTB33,JAK1,BAG2,GRM8,TSEN54,SERPINB10,MCM8,UTP15,FBXO42,HP1BP3,MX2,DLAT,FZD4,MIOS,PPP1R2,MRPL50,SLC30A5,KLK3,NETO2,SMARCD3,RAG1,SFN,RING1,ENY2,GNAI3,TRAPPC10,TRIM46,DNAJC1,OVGP1,SWAP70,MYL12A,ITK,EIF4H,JAKMIP1,TIAM1,TRIM63,SENP5,CTNNBL1,IDH3B,APOBEC3A,ID4,RHBDD3,PPP5C,XAGE5,LDLR,FOXP3,CCR6,CLU,ANAPC11,LMO4,RASGEF1C,MAD2L1,CDK5R1,MAP2K6,ASB8,INPP5E,CDC16,LTBR,CASK,GNB1,GLTP,IRF1,CUL2,PYCARD,SLC6A8,TRIM23,ARMCX1,UBE2A,GHR,CCT2,CXCL11,UBE2D3,SOCS4,SOX3,RPS4X,MAP3K12,ZDHHC15,RSPH1,E2F6,ZMPSTE24,FBP2,CD99L2,PRIM2,TRIM32,NFE2,RNF141,KLK9,ALKBH2,DOK4,ARHGAP1,NCKIPSD,LIG3,PRKCQ,SLC17A5,IKZF2,PGM1,TRIM3,GTF2IRD1,IKBKB,AKT1,FGD2,L1CAM,HRAS,RAB11A,ASMT,PRRC2A,TRIM8,DKK3,CNP,TFG,RND3,CDK8,PFDN5,PHF23,COX10,EHBP1,MDM2,MRPL13,WDR83,CCDC69,AK2,SOCS5,CXCL9,RBPJ,DUSP9,AKR1A1,IFNK,BPGM,CDKN3,EGLN2,RNF152,NUP107,DEK,SLC5A6,PRKD3,TCOF1,POU1F1,CYC1,SLC35A2,MCPH1,NKRF,PTDSS1,ID1,KIF2A,RGS10,INPPL1,ASB1,FBXL3,ITM2A,ADH1A,BMPR1A,ARHGAP21,MCM6,RHCG,DIRAS1,KLF10,CCND1,SASH3,CASP4,FBXO9,COX7A1,SPOP,NR0B1,BCL2L1,AP1G2,DCAF8L2,ACVR1,ANP32B,MYH1,IFT57,NFYA,PPP1CC,DUSP1,BATF,BAZ1B,NOP16,RAB3C,MTAP,TNFRSF9,LRRC8C,DMAP1,UBE2N,CTNNB1,RAB8B,SOCS2,FKBP4,PSKH1,SMURF1,P2RY10,SLC38A2,CDK6,TAF2,SGMS2,ANXA7,NCSTN,COL3A1,CBX7,USP38,QSER1,USP39,CERK,TLR4,NAB1,IL5,LSM6,PEBP1,PROX1,PRKX,CX3CL1,FGF13,NCOA5,RUVBL2,IGF2BP1,SIKE1,SOST,SNX3,DBH,TSSC4,ALDH1L1,USP46,SMAD2,NONO,PITPNB,POLL,GNAQ,SPRED1,RAD1,NFE2L2,ETV6,RABIF,SIRT7,FYTTD1,TRAF7,CDC5L,MTMR12,DUOXA2,SLC35A5,RAP2B,TNFAIP3,KCNH8,WWP2,RAP1A,FBXO30,RASGRP2,ST13,MMP14,RAB6B,RAB28,MDH1,ELK1,MRAS,NEDD8,CXCR1,COPS4,KCNK17,LMBR1L,CBL,GAS8,CDKL2,KDM2A,POLD2,GXYLT1,EXOSC8,LHFPL1,SUMO1,HSPB1,DCLRE1C,RAB4A,DHX16,SERPINH1,PIK3R1,HSPE1,TSPAN7,STAMBPL1,MAPRE2,EPHA2,NLE1,SRSF1,ITGA2,COX6B1,PDIA3,XPOT,LMBRD1,CXCL1,FAM3A,NEK9,TNFSF10,FMO3,FURIN,CDK5RAP3,AGAP2,FBXO3,ACHE,UBE2B,CSE1L,NEK7,PHKG1,NTRK3,PICK1,TSSK1B,CIRBP,ENDOD1,SAP30L,RNF146,TXNRD3,APOBEC3C,XPO5,POU3F4,RNF103,IDH3A,RFC5,THRAP3,EEF2,MED13L,NSDHL,XPO1,EXOC2,FATE1,HECTD3,DNAL4,HDAC5,RC3H2,UBL4A,THOC1,GSK3A,GAPDH,LDHA,VAC14,YES1,GRIA1,PSMB10,CDK17,ATP6V1D,CDKN2D,BCL2A1,TFDP2,SUPT4H1,VPS39,ZNF189,EEF1B2,PTPRZ1,MPP1,ETFB,RANBP10,BMPR1B,TULP3,FBXO11,MLH3,PCBP4,FAM193B,SPSB1,APOBEC3B,RBBP9,WNT10B,FOXC2,RAB32,PITPNA,CKS1B,AUH,TFRC,RGL1,SUV39H1,PRKCB,HMGA1,FOXI3,PABPC5,MND1,RBM41,LCP1,PCYT1B,PRELP,GJB1,SKP1,DNAJC7,ADAMTS20,HDAC11,DUSP22,PLCL1,DIRAS3,YWHAH,GABRB3,SMAD9,PTPN5,FOXJ3,USP30,JUNB,RAD23B,VCPIP1,TCEA1,BCAS4,CHN2,HBEGF,CACNB2,SLITRK1,DDIT3,SHC3,CDC26,SMYD3,DDIT4,STK38L,PIGC,RAB3A,CTNND1,KPNA2,FAM91A1,CCND3,RAB11B,ARL6,SNX12,IRF4,CMTM7,NEURL2,PLP2,ABCF1,NDP,RNF139,NUP62,SMG5,USP13,FGF3,RPAP3,RAB9A,IL7,TNPO2,SRSF4,SH3BGRL,APPBP2,PPP2R5A,SLITRK5,TLR7,SAP30,FGF16,MSN,POU5F1,VASH1,PTGES,MAGEB1,DICER1,RNF128,NAA15,SYBU,SERPINB6,FTHL17,WDR55,RALA,G6PD,ADK,MID1IP1,TDP1,MED29,BRMS1L,UBE2I,MFAP1,MXD1,HCST,FBXO34,ZBTB16,PNRC1,OGDHL,CAPG,EZH1,TLR1,RNF7,SAR1B,CCR5,MAP3K3,ARF6,FBXL7,LBR,FGR,SPHK2,RCHY1,CXXC1,STYK1,MAP2K3,DOK5,TFPT,RIT2,ALOX5AP,SLC25A14,PRDX4,NUP35,MECP2,ZC4H2,TBC1D19,CETN2,CBFB,ZC3H14,ASPM,RGS6,SMARCE1,ENO1,UBE3A,SERPIND1,CHST7,ORAI2,TNIK,PML,DNASE1L1,ARF4,SERTAD1,ARF1,GNG11,HMGB1,DUSP6,PDCD5,BTBD10,ASB11,RGS1,SDHC,RHOG,NOL12,FAM83A,COX7B,METTL18,RSBN1L,TMED4,KPNA6,TOX,TP53,DUSP18,TAX1BP1,SMUG1,KIN,CDH7,ASCC1,CXCL10,SENP8,GPC4,FOXD3,FBLN5,TRIM35,PPM1B,AKAP1,PSMA6,HMGN4,NLGN1,COX7B2,CDKN1B,TRIM62,SYK,ACO2,CDC42,AHSA1,PLEKHF1,DUSP10,STRADB,SIAH1,NCK1,IL2RG,SNX1,CCM2,PSEN2,HERC3,PTGER2,MYC,CD40LG,RAB35,BRS3,PPP1R8,ZMAT3,TRAF1,RASSF4,SERPINA3,CLK1,GEMIN8,PRPS1,GPR173,TOP2B,TSPAN3,BAD,VAPB,CALML5,SP2,PDCD10,GMNN,RALB,UNC45A,FKBP2,CCDC22,RNF40,KDM1A,DDX1,TP53I3,SNRPA1,ABHD2,BIRC5,FGF23,RANBP6,LDB1,SFRP1,ELF1,WSCD1,PNMA5,OXCT1,ENO2,PSENEN,UBE2H,CAMKV,ARL5B,RNF11,CYTH2,TMEM176B,RPL22,WDR82,DLG3,OR4S2,RHOU,IFRD1,ACSS2,DNAJC2,GNB1L,ATF3,RANBP1,MET,FZD6,SSH3,CRADD,PPP1R3C,IMP4,HELT,MCMBP,PDE6A,SERPINB9,S1PR4,UBE2V1,SNX11,AKAP17A,RAD21,RAP1B,DNAJB4,AIFM1,SNX14,TIMM8A,EGR1,ACTL6A,ACVR1B,ANAPC4,ARHGAP15,RHOH,UBE2S,LRRC4B,PIK3CG,COX4I1,MAGEA4,RBM3,HDAC3,GLRA2,RACGAP1,CORO1C,CHMP2B,PAK6,GRB10,CSNK1E,AKT3,BCKDK,POLD4,DNAJC4,OR5A2,ARMCX3,NAP1L3,CUL3,ARHGAP19,FAS,ATF1,ERCC3,COX6A2,XBP1,MAD2L2,RBBP4,GPR34,ALG5,SMARCB1,MMP20,OR4K13,ENC1,PLCXD3,TRIM6,FOXP1,SLC4A10,RFC4,OR2D3,COTL1,KCNS1,FKBP1A,APEX1,GAB1,AKT2,RNF5,FBXO31,PIGK,EEF1A1,GAS2,AMELX,RAB1A,GLO1,PRKCA,PDCD1LG2,BRD3,TESK1,DVL2,RPL39,ALDH1A3,AHCYL1,CLIC4,ANKRD10,HNRNPH2,MDC1,SP1,MGMT,TADA3,TRAM1,LANCL2,FUNDC1,PRKACB,ASB7,FEN1,IMPA2,SPRY1,ETNK2,CNOT2,MYBL2,PLEKHO1,ZNF326,ERAS,TKTL1,SCML2,DNAJC19,ELF5,TRAF6,ROCK2,KRIT1,SIAH2,CIAO1,CER1,BIRC2,MTM1,DUSP3,FCGR2B,SUCLG2,UMPS,SCML1,TAPT1,TYMS,MRPL22,SS18,NAA16,SLC12A2,RUNX1,GJC1,IGF1R,CX3CR1,MAVS,ARHGAP12,UBP1,DIRAS2,ORC6,DROSHA,STARD4,THOC2,EDA2R,FKBP1B,LMO2,FAM177A1,PSEN1,MCM4,MAGEC2,OR13A1,TANK,TNFRSF1B,MPG,TGFBR2,DMPK,CAPN1,USP3,CDC23,CYP2C8,LRRC8A,GNGT2,OR5M9,HAUS2,RP9,NKAP,RABGGTB,FBXO7,RPL23,SPIN3,VAMP7,CTTN,RASL12,SMAD1,GABPA,FKBP8,PPP2CB,RRAGB,CCR7,TTL,RXRG,SNAP25,PPP3R2,TIMP3,GMPS,RNF8,PEA15,FXN,UPRT,EP300,ADAMTS10,UBE2G2,STAT5A,COPS5,TRIM26,MAGEH1,OTX2,EIF4A2,FEZ1,PLCB2,MAP2K1,APOBEC3F,CYTH4,FAM3C,PTP4A2,PTPN4,RIT1,ELOVL1,EFNA3,TPM3,SNRPB,AR,ADCK1,ZNF518B,PPM1K,SLC25A5,NLRP9,WSB1,LYZ,TOPORS,LAMP2,GNA11,SERPINB1,HSPA5,SRSF2,HSPB6,ST7,SNRK,WDR45,NKIRAS2,ACVR1C,IL1R2,PQBP1,GPRASP2,PIP4K2C,STUB1,PPP2R2C,STK4,TNKS,SLC22A17,PLS3,TRIM44,CYP1A1,GNB3,HINFP,VAV2,ITGB8,BTG2,GADD45A,GRPR,SYNCRIP,TRMT112,BTG3,GLOD4,PIGA,RNF148,PPP1R1A,MSTN,SPSB3,DDR1,UGT1A1,SAP18,PNPLA4,PIAS1,POLA2,POLB,KIAA0513,EIF1AX,HSPD1,CCNH,UNC79,FBXL4,PTPN11,NOTCH2,CCR1,LDB2,DTWD1,RPA2,ASTN1,TP53INP1,TRAF3IP3,FAF1,SRPK2,TAB2,ARFGEF1,TLR8,CD40,TNFSF15,CRY1,PLAC1,SIN3A,CDK7,TCEAL1,USP16,RAB6A,FKBPL,RGN,TNFSF8,RNF10,POLE3,NFKBIA,NCAPG2,ETF1,CNPY3,CYP4V2,PPP1R11,KLF4,COPS7B,DENND2D,MSH6,RAP2A,RNF34,OR4D5,RFC3,GPM6B,IP6K1,FBXO22,FBXW4,P2RY4,SERPINC1,HLF,RPL10,CXCL13,RORB,CKS2,STAMBP,CCDC160,MOXD1,SNRNP48,SDHB,PCGF6,TAF1D,SPATA2,ADORA1,MAGEB10,CXCR3,UAP1,CCNA2,MAGED2,RLIM,PTEN,SURF2,TNR,BOK,SLC8A1,YWHAZ,ICAM2,GNAZ,PLCB1,DNAJB9,RNF144B,SPP1,NTRK2,GNG12,APOBEC3G,TSR2,USP15,FBXW7,CDK12,ARL4D,CITED1,PSMD10,TNNI3K,EPHA4,RB1,TRIM29,PNMA3,ZBED1,DKC1,FBXO44,HR,NDUFA1,PLD3,MCL1,TMEM127,NT5DC1,TRIM36,JAK2,NDUFS6,DDX23,PCNA,PDE1B,PIK3R2,SPRED2,DCAF12L2,FZD3,RHOBTB1,PTP4A3,NXT2,HSPB2,STK3,TNKS2,COX8A,HUWE1,ABHD10,CPLX2,USP8,PTK7,FTSJ1,DHX38,PGRMC1,CSNK1G3,RAB39B,CYP3A43,PDE4B,UBE2L3,PMAIP1,TCEAL8,BCL7C,NINJ1,FBXW11,RGL2,ITGB5,PPFIA2,TRIM34,FBXO8,ST6GAL1,CDC7,TRIM45,SRSF7,DUSP21,SAV1,STAT2,CBLL1,RBBP8,UBA3,SGMS1,TIMP4,XRCC5,GNAO1,CDC20,SNX22,IL2,NBN,PEX13,TBC1D25,IRAK4,WDR11,NHEJ1,FHOD3,UBE2E2,RPS6KA4,GANAB,RHOBTB3,DDX46,OCRL,DPH3,ELK3,CD81,GRAP2,RAB27A,COX6B2,RNF133,ZNF451,PRKCE,TSPAN17,FBXL14,RHEB,SESTD1,SH2D1A,PPP2R5E,FOXA3,PARP2,NF2,HSPA13,DAAM1,LRRTM3,SERPINA1,SUMO2,CCR4,KLF3,TNF,TMEM185A,PIK3CA,CDH11,CHIC2,TMEM47,FBXL19,AP1S2,APEX2,SF3B1,MTA2,DAPK3,COCH,RAPGEF5,COX6C,PICALM,SLC16A1,NUF2,TMEM101,CRTC2,NPM3,BAX,NLRP3,CBX3,RASD1,PPP1R1B,RND2,BMPR2,BCL9,PRNP,CAND1,HSD17B10,IER2,SNX10,ZMYM3,USP6NL,DKK1,HERC4,RBM22,RRM1,KRAS,BCL6,BAG3,OXSR1,ORC5,DLST |
| 1.196e-05 | -11.33 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5198 | 1609 | 16828 | 4835 |
DHX16,RAB4A,DCLRE1C,HSPB1,LHFPL1,SUMO1,EXOSC8,GXYLT1,POLD2,KDM2A,STAMBPL1,TSPAN7,HSPE1,PIK3R1,SERPINH1,NLE1,EPHA2,MAPRE2,CXCL1,LMBRD1,XPOT,PDIA3,COX6B1,ITGA2,SRSF1,RAB6B,MMP14,ST13,RASGRP2,FBXO30,RAP1A,WWP2,NEDD8,CXCR1,MRAS,ELK1,MDH1,RAB28,KCNK17,COPS4,CDKL2,GAS8,CBL,LMBR1L,APOBEC3C,TXNRD3,EXOC2,XPO1,MED13L,NSDHL,THRAP3,RFC5,EEF2,IDH3A,RNF103,POU3F4,XPO5,THOC1,UBL4A,RC3H2,HDAC5,DNAL4,HECTD3,FATE1,GRIA1,YES1,VAC14,LDHA,GAPDH,GSK3A,CDK5RAP3,FURIN,FMO3,TNFSF10,NEK9,FAM3A,UBE2B,CSE1L,ACHE,FBXO3,AGAP2,TSSK1B,PHKG1,PICK1,NTRK3,NEK7,SAP30L,RNF146,ENDOD1,CIRBP,DIRAS1,KLF10,RHCG,MCM6,ARHGAP21,BMPR1A,ADH1A,ITM2A,NR0B1,SPOP,COX7A1,FBXO9,CASP4,CCND1,SASH3,IFT57,MYH1,ACVR1,ANP32B,DCAF8L2,AP1G2,BCL2L1,DMAP1,LRRC8C,TNFRSF9,MTAP,RAB3C,NOP16,BAZ1B,BATF,DUSP1,PPP1CC,NFYA,IFNK,AKR1A1,DUSP9,RBPJ,CXCL9,PRKD3,SLC5A6,DEK,NUP107,RNF152,EGLN2,CDKN3,BPGM,ID1,PTDSS1,MCPH1,NKRF,SLC35A2,CYC1,POU1F1,TCOF1,FBXL3,ASB1,INPPL1,RGS10,KIF2A,DBH,SNX3,SOST,SIKE1,IGF2BP1,RUVBL2,NCOA5,NFE2L2,RAD1,SPRED1,GNAQ,POLL,PITPNB,NONO,SMAD2,USP46,ALDH1L1,TSSC4,FYTTD1,SIRT7,RABIF,ETV6,KCNH8,TNFAIP3,RAP2B,SLC35A5,MTMR12,DUOXA2,CDC5L,TRAF7,SMURF1,PSKH1,FKBP4,SOCS2,RAB8B,CTNNB1,UBE2N,ANXA7,NCSTN,SGMS2,TAF2,CDK6,SLC38A2,P2RY10,TLR4,CERK,USP39,QSER1,USP38,COL3A1,CBX7,FGF13,CX3CL1,PRKX,PROX1,PEBP1,LSM6,IL5,NAB1,CCR6,FOXP3,LDLR,XAGE5,PPP5C,RHBDD3,ID4,APOBEC3A,MAP2K6,CDK5R1,MAD2L1,RASGEF1C,LMO4,ANAPC11,CLU,GLTP,GNB1,CASK,LTBR,CDC16,INPP5E,ASB8,SOCS4,CXCL11,UBE2D3,CCT2,GHR,UBE2A,ARMCX1,TRIM23,SLC6A8,PYCARD,CUL2,IRF1,PPP1R2,MIOS,TRAPPC10,GNAI3,RING1,ENY2,RAG1,SFN,NETO2,SMARCD3,KLK3,SLC30A5,MRPL50,EIF4H,ITK,MYL12A,SWAP70,OVGP1,DNAJC1,TRIM46,IDH3B,CTNNBL1,SENP5,TRIM63,TIAM1,JAKMIP1,L1CAM,FGD2,AKT1,IKBKB,DKK3,TRIM8,PRRC2A,ASMT,RAB11A,HRAS,COX10,PHF23,PFDN5,CDK8,RND3,TFG,CNP,AK2,SOCS5,CCDC69,WDR83,MRPL13,MDM2,EHBP1,FBP2,ZMPSTE24,E2F6,ZDHHC15,RSPH1,MAP3K12,RPS4X,SOX3,NCKIPSD,DOK4,ARHGAP1,KLK9,ALKBH2,RNF141,NFE2,TRIM32,PRIM2,CD99L2,PGM1,SLC17A5,IKZF2,PRKCQ,LIG3,GTF2IRD1,TRIM3,DRP2,DYRK1A,ARMCX5,RAB31,FKBP14,IDH2,INSM2,NEUROD6,RAB18,AGER,EIF2AK2,LGI3,C1GALT1C1,COPS2,TRIM27,ANAPC2,FBXO32,AGK,SHC1,FGFR1,CD200R1,PPP3CA,NME2,UBAC2,SRP54,CAMK2G,PCK2,RALGAPA2,ACO1,CIB3,SATB1,SCFD1,NELL2,FAM199X,RABL2B,ARHGEF6,CYP4F12,USP2,FRMD8,ADRB1,ZDHHC14,RBM17,HEY2,ARMCX2,SIX5,TRIM21,ARFIP1,SNX2,CAMK1,BCCIP,PTPN1,PTTG1,HECW1,TRIM37,RBBP7,SEC63,MCAT,NOVA1,RMND5B,DEFB116,GRAP,RAB3B,BAG2,JAK1,ZBTB33,MLF1,HP1BP3,FBXO42,UTP15,MCM8,SERPINB10,TSEN54,GRM8,FZD4,DLAT,MX2,PGK1,VRK1,EXT1,JUP,MSRB3,DNAJC5,KLRD1,ZMYM2,OR4N5,SNX5,S100A6,CFL2,BUB3,MMP9,RNF41,DCAKD,PLP1,AFTPH,LMNA,PHF1,CYP3A5,KIT,RS1,CSNK2A1,KPNA1,GNG7,CTNNBIP1,TMEM74,ABHD14B,LGR4,EED,CIB2,TRIM24,ACSL4,PPP1R12A,TFEB,HSCB,HSPA8,VMP1,GOLGA5,OSBP,DNTT,MED21,LMNB1,BECN1,SSRP1,AK5,UBE2V2,RAB22A,SMC4,TSPO2,FCHSD2,EFNB1,RNF113A,MOSPD1,PREPL,UBE2E3,TRIM10,TFE3,PIR,UBE2M,ITGA6,CSNK1A1,IGBP1,AKAP12,DDX39A,LDHB,RNF126,FOXP4,FERD3L,MXI1,USP5,ITGAV,CDKN2C,COX4I2,TM9SF4,EIF4E,TRIM5,LRRC1,NUP37,SLC1A3,SMAD4,FZR1,PPP2R3A,CD274,FAIM,ELK4,BAK1,DRAM1,SMARCA5,SOCS3,PTPN22,PDRG1,FOLR2,CEP97,CD1A,RAC2,MMP21,NFKBIB,STK24,LRP6,RNF121,PGAM1,PCMTD2,PAX9,ACTB,CNTN1,GNB4,PRKAB1,DERL1,RFC2,TYW3,SNX18,SOX2,LNX2,CSNK1A1L,SERINC3,DNAJC3,KLK6,ZBTB2,PLA2G12A,STAU1,TSN,PFDN4,NPR2,CDK4,GABRA2,TRAF2,RAB30,BRCA1,PCDHB1,DNAJB2,KCNMA1,NOS1AP,BCL10,PDHA1,PPP4C,NME1,DUSP19,RGS2,NKIRAS1,GIT2,RUVBL1,RAB3D,ICAM3,KDM4B,RGS19,RASGRP3,MGAT1,RCE1,TRIM54,MCM3,CDC42EP3,RAB33B,CREBBP,PDCD4,LDOC1,METTL2A,NLRP6,CHRDL1,AKAP14,CCNB1,FAM162A,PIP5K1A,ERH,IZUMO1,UHMK1,TRAF3IP2,PTGER4,GNG2,TERT,MORC4,GTF2H2,MAP3K11,PIK3R3,SRC,CD2AP,GNG13,SAT1,IDH1,RASL10A,CCR2,DSTYK,GNG5,IPO8,HMG20A,GPHN,POLE4,HSP90AB1,FUNDC2,ATG4A,SYP,PADI2,CSRNP1,SFRP4,DNAJC22,HTR5A,ARHGAP25,BCL7B,OPRK1,PGPEP1,F9,CXCL12,FLCN,PPM1D,IDO1,SERPINI1,SNX17,TMC7,APOO,TOP1,TNFSF13,CDK5,GNG3,RAB13,RNF26,RNASEL,UTP23,DNAJC8,TNFSF18,TOB2,RNF167,RAB33A,CCR3,OGG1,OPHN1,SUMO3,SLC45A3,PTGER1,PPFIBP1,RAB23,WWP1,RHOJ,CBLN4,ADCY2,PKIG,JUN,ZNF507,STAT1,PAX6,FANCG,MSX1,RFTN2,PPID,RPN1,TLR6,DYNLT3,OR4N4,EGLN3,FOS,DYRK2,SDC4,POMP,RPL26,RIOK2,RAB14,HNRNPK,APOBEC3D,PRKAG1,PC,RAB5A,NFKB1,NEK2,MAFG,F10,SCD5,TMEM31,RRAS2,ADAMTS1,CXCL14,RERG,BNIP3L,OTUD6A,NUP153,RNF20,DDX42,COPS7A,PPP1R16A,PGR,LCN9,HSPA14,CXCR4,NPY5R,PAFAH1B2,ANAPC13,RNF39,PBLD,HDAC6,RNF122,ASB3,BICD2,BTG1,SERPINA5,ZMYM4,CXCR6,GNA14,RBM12,RAN,USP14,TSC22D3,NR1H2,MMADHC,PHB2,APLN,TMEM164,YWHAB,CDSN,PLEKHA8,NUS1,ARRDC3,ZCCHC12,UPF3B,RABL3,PPP1CB,NFYB,SESN2,DAPK1,KLHL15,UBE2D1,SNIP1,RGS5,RAB1B,GSTK1,RBMX2,TNFRSF14,LDHAL6B,FOXN2,RP2,CDKN1A,SLITRK2,FBP1,STX18,NLRP1,CLIC2,PPFIA3,SOS2,CRKL,STARD13,DNAJC27,KDSR,CD1D,E2F4,TAF5L,FLRT2,PPM1G,MAX,TCEAL7,RHOB,PCGF3,PROM1,TRIM11,G2E3,CDH8,TOPBP1,GRIA2,GNAI2,DDX4,KLK5,CAB39,CBX5,SLC43A2,TOP3B,PEX5L,EZH2,FKBP10,INPP4A,RAB9B,RPS27L,WIF1,FN3KRP,TESK2,DYRK1B,STK11,ISG15,TP53INP2,GPSM3,SNX24,STAT6,LAMTOR3,ARL4A,LITAF,CCNF,CTNNA1,RAB2A,MEF2C,WDR44,FUT1,RPRM,RAB37,SCYL2,FBXO25,PHKA1,RAF1,DNAJC10,PRRG1,STK38,PNP,RAB5C,RNF14,PCDH19,WEE2,DET1,EIF4A3,DDX5,PPP2R1A,SMAD3,RAP2C,TIMP1,FOXP2,UBE2F,CYTH1,IL6ST,CD81,DPH3,ELK3,OCRL,DDX46,RHOBTB3,RPS6KA4,GANAB,UBE2E2,RHEB,FBXL14,TSPAN17,PRKCE,ZNF451,RNF133,COX6B2,RAB27A,GRAP2,LRRTM3,DAAM1,HSPA13,NF2,PARP2,FOXA3,SH2D1A,PPP2R5E,SESTD1,TNF,KLF3,CCR4,SUMO2,SERPINA1,CDC7,ST6GAL1,FBXO8,SGMS1,UBA3,RBBP8,CBLL1,STAT2,SAV1,DUSP21,SRSF7,TRIM45,SNX22,CDC20,GNAO1,XRCC5,TIMP4,FHOD3,NHEJ1,WDR11,IRAK4,TBC1D25,PEX13,NBN,IL2,BCL9,BMPR2,PPP1R1B,RND2,RASD1,CBX3,NLRP3,IER2,PRNP,CAND1,HSD17B10,HERC4,DKK1,USP6NL,ZMYM3,SNX10,DLST,ORC5,OXSR1,BAG3,BCL6,KRAS,RRM1,RBM22,CDH11,PIK3CA,TMEM185A,SF3B1,MTA2,APEX2,AP1S2,FBXL19,TMEM47,CHIC2,TMEM101,NUF2,SLC16A1,PICALM,COX6C,RAPGEF5,COCH,DAPK3,BAX,NPM3,CRTC2,RNF144B,DNAJB9,PLCB1,GNAZ,USP15,TSR2,APOBEC3G,GNG12,NTRK2,SPP1,CDK12,FBXW7,EPHA4,TNNI3K,PSMD10,CITED1,ARL4D,MOXD1,CCDC160,STAMBP,CKS2,RORB,CXCL13,CXCR3,MAGEB10,ADORA1,SPATA2,TAF1D,PCGF6,SDHB,SNRNP48,SURF2,RLIM,PTEN,MAGED2,CCNA2,UAP1,ICAM2,YWHAZ,SLC8A1,BOK,TNR,RAB39B,CSNK1G3,PGRMC1,DHX38,FTSJ1,PTK7,CPLX2,USP8,ABHD10,HUWE1,COX8A,PMAIP1,UBE2L3,PDE4B,CYP3A43,BCL7C,TCEAL8,TRIM34,RGL2,ITGB5,PPFIA2,FBXW11,NINJ1,HR,FBXO44,DKC1,ZBED1,PNMA3,TRIM29,RB1,TMEM127,MCL1,NDUFA1,PLD3,SPRED2,PDE1B,PIK3R2,PCNA,DDX23,JAK2,NDUFS6,TRIM36,NT5DC1,TNKS2,STK3,NXT2,HSPB2,RHOBTB1,PTP4A3,FZD3,DCAF12L2,BTG3,TRMT112,SYNCRIP,GRPR,GADD45A,MSTN,PPP1R1A,RNF148,GLOD4,PIGA,SAP18,UGT1A1,DDR1,SPSB3,EIF1AX,CCNH,HSPD1,KIAA0513,POLB,POLA2,PNPLA4,PIAS1,WDR45,SNRK,ST7,HSPB6,SRSF2,SERPINB1,HSPA5,GNA11,STUB1,PIP4K2C,GPRASP2,PQBP1,IL1R2,ACVR1C,NKIRAS2,CYP1A1,TRIM44,PLS3,SLC22A17,TNKS,STK4,PPP2R2C,BTG2,ITGB8,VAV2,HINFP,GNB3,CYP4V2,CNPY3,ETF1,NCAPG2,NFKBIA,POLE3,RNF10,OR4D5,RNF34,RAP2A,MSH6,DENND2D,COPS7B,KLF4,PPP1R11,SERPINC1,HLF,P2RY4,FBXW4,FBXO22,IP6K1,GPM6B,RFC3,RPL10,NOTCH2,PTPN11,FBXL4,UNC79,SRPK2,TAB2,FAF1,TRAF3IP3,TP53INP1,ASTN1,RPA2,DTWD1,LDB2,CCR1,CRY1,TNFSF15,CD40,TLR8,ARFGEF1,TNFSF8,RAB6A,FKBPL,USP16,RGN,TCEAL1,CDK7,SIN3A,PLAC1,FCGR2B,SUCLG2,DUSP3,BIRC2,MTM1,CER1,CIAO1,SIAH2,GJC1,SLC12A2,RUNX1,NAA16,SS18,MRPL22,TYMS,TAPT1,SCML1,UMPS,DIRAS2,UBP1,MAVS,ARHGAP12,CX3CR1,IGF1R,OR13A1,MCM4,MAGEC2,PSEN1,FAM177A1,FKBP1B,LMO2,EDA2R,THOC2,STARD4,DROSHA,ORC6,MGMT,SP1,MDC1,IMPA2,FEN1,PRKACB,ASB7,FUNDC1,TADA3,LANCL2,TRAM1,ERAS,ZNF326,MYBL2,PLEKHO1,CNOT2,ETNK2,SPRY1,KRIT1,ROCK2,ELF5,TRAF6,DNAJC19,SCML2,TKTL1,UBE2G2,ADAMTS10,EP300,UPRT,FXN,PEA15,RNF8,CYTH4,APOBEC3F,PLCB2,MAP2K1,FEZ1,EIF4A2,MAGEH1,OTX2,STAT5A,COPS5,TRIM26,SNRPB,TPM3,EFNA3,ELOVL1,RIT1,PTPN4,PTP4A2,FAM3C,LAMP2,LYZ,TOPORS,WSB1,NLRP9,SLC25A5,PPM1K,ADCK1,ZNF518B,AR,CYP2C8,CDC23,USP3,CAPN1,DMPK,TGFBR2,MPG,TNFRSF1B,TANK,CTTN,VAMP7,SPIN3,RPL23,RABGGTB,FBXO7,NKAP,RP9,OR5M9,HAUS2,GNGT2,LRRC8A,RRAGB,PPP2CB,FKBP8,GABPA,SMAD1,RASL12,GMPS,TIMP3,PPP3R2,SNAP25,RXRG,TTL,CCR7,CSNK1E,GRB10,PAK6,CHMP2B,DNAJC4,BCKDK,POLD4,AKT3,ARHGAP19,CUL3,ARMCX3,NAP1L3,OR5A2,GPR34,RBBP4,MAD2L2,COX6A2,XBP1,ERCC3,ATF1,FAS,EGR1,TIMM8A,AIFM1,SNX14,DNAJB4,AKAP17A,RAD21,RAP1B,ACVR1B,ACTL6A,PIK3CG,COX4I1,LRRC4B,UBE2S,RHOH,ANAPC4,ARHGAP15,CORO1C,RACGAP1,GLRA2,RBM3,HDAC3,MAGEA4,PDCD1LG2,PRKCA,GLO1,RAB1A,AMELX,GAS2,EEF1A1,PIGK,FBXO31,RPL39,DVL2,TESK1,BRD3,AHCYL1,ALDH1A3,HNRNPH2,ANKRD10,CLIC4,SMARCB1,ALG5,FOXP1,SLC4A10,TRIM6,PLCXD3,ENC1,OR4K13,MMP20,AKT2,GAB1,APEX1,FKBP1A,KCNS1,COTL1,OR2D3,RFC4,RNF5,CD40LG,MYC,PTGER2,HERC3,CLK1,SERPINA3,RASSF4,TRAF1,ZMAT3,PPP1R8,BRS3,RAB35,BAD,TSPAN3,TOP2B,PRPS1,GPR173,GEMIN8,PDCD10,SP2,CALML5,VAPB,PSMA6,AKAP1,CDKN1B,COX7B2,NLGN1,HMGN4,DUSP10,AHSA1,PLEKHF1,CDC42,ACO2,SYK,TRIM62,PSEN2,CCM2,SNX1,IL2RG,NCK1,SIAH1,STRADB,RHOU,OR4S2,DLG3,WDR82,RPL22,TMEM176B,RNF11,CYTH2,RANBP1,ATF3,GNB1L,DNAJC2,ACSS2,IFRD1,SSH3,FZD6,MET,SNX11,UBE2V1,S1PR4,SERPINB9,PDE6A,MCMBP,HELT,IMP4,CRADD,PPP1R3C,FKBP2,UNC45A,RALB,GMNN,ABHD2,SNRPA1,TP53I3,KDM1A,DDX1,RNF40,CCDC22,WSCD1,ELF1,SFRP1,LDB1,RANBP6,FGF23,BIRC5,ARL5B,CAMKV,UBE2H,PSENEN,OXCT1,ENO2,PNMA5,RCHY1,SPHK2,FGR,LBR,FBXL7,ARF6,DOK5,MAP2K3,STYK1,CXXC1,SMARCE1,RGS6,ASPM,CBFB,ZC3H14,CETN2,ZC4H2,TBC1D19,MECP2,NUP35,SLC25A14,PRDX4,RIT2,ALOX5AP,TFPT,TNIK,ORAI2,SERPIND1,CHST7,UBE3A,ENO1,RNF128,DICER1,MAGEB1,PTGES,VASH1,POU5F1,FGF16,MSN,SAP30,TLR7,SLITRK5,PPP2R5A,TDP1,MID1IP1,ADK,G6PD,WDR55,RALA,FTHL17,SERPINB6,SYBU,NAA15,PNRC1,ZBTB16,FBXO34,HCST,MXD1,MFAP1,UBE2I,BRMS1L,MED29,MAP3K3,SAR1B,CCR5,RNF7,TLR1,EZH1,CAPG,OGDHL,COX7B,FAM83A,NOL12,RHOG,SDHC,RGS1,ASB11,TOX,KPNA6,TMED4,RSBN1L,METTL18,ASCC1,KIN,CDH7,SMUG1,TAX1BP1,DUSP18,TP53,PPM1B,TRIM35,FBLN5,FOXD3,GPC4,SENP8,CXCL10,DNASE1L1,PML,SERTAD1,ARF4,HMGB1,GNG11,ARF1,BTBD10,PDCD5,DUSP6,SUV39H1,RGL1,TFRC,AUH,CKS1B,RBM41,MND1,FOXI3,PABPC5,HMGA1,PRKCB,SKP1,GJB1,PRELP,PCYT1B,LCP1,GABRB3,DIRAS3,YWHAH,PLCL1,DUSP22,HDAC11,ADAMTS20,DNAJC7,BCL2A1,CDKN2D,ATP6V1D,CDK17,PSMB10,EEF1B2,PTPRZ1,ZNF189,VPS39,SUPT4H1,TFDP2,TULP3,BMPR1B,RANBP10,ETFB,MPP1,RAB32,PITPNA,FOXC2,WNT10B,RBBP9,APOBEC3B,SPSB1,FAM193B,PCBP4,FBXO11,MLH3,NEURL2,CMTM7,IRF4,SNX12,RAB11B,ARL6,CCND3,FGF3,USP13,RNF139,NUP62,SMG5,NDP,ABCF1,PLP2,SH3BGRL,SRSF4,TNPO2,IL7,RAB9A,RPAP3,APPBP2,RAD23B,JUNB,USP30,FOXJ3,PTPN5,SMAD9,HBEGF,CHN2,BCAS4,TCEA1,VCPIP1,DDIT3,SLITRK1,CACNB2,FAM91A1,KPNA2,CTNND1,RAB3A,PIGC,STK38L,SMYD3,DDIT4,CDC26,SHC3 |
| 1.208e-05 | -11.32 | MYH10 (myosin heavy chain 10) | protein interactions | 4628 | 305 | 120 | 19454 | 5460 |
ACTB,LGALS3,RBBP4,PRMT5,EFHD2,HTRA2,SP1,BRCA1,BTF3,RAB11A,CUL3,MYC,STAU1,FXR2,UFL1,EP300,DDX39B,MYL6,PAK2,PRKAB1,WDR77,RMND1,FHIP1B,HNRNPL,EED,PPP2CB,PHB1,MAGOH,BCL2L1,CBL,AGR2,DDX23,CTNNB1,YWHAG,AHCYL1,DPM2,TRIM37,RUVBL1,G3BP1,PSMA1,KRAS,TOP2B,SMARCB1,MTA2,NGB,CHMP4C,EZH2,LGR4,PPP2R1A,ISG15,MED9,RAF1,TOP3B,DEK,VIRMA,GNAI2,ADRM1,NDN,RALA,UBASH3B,TRIM24,PTEN,PSMC5,EIF4A3,CCNF,UBE2H,AR,HSPA5,PIAS1,SMC4,PIK3R2,FBXW7,SIRT7,BAP1,RPA3,HECTD1,ACACA,UBE2M,METTL14,RPA2,DCTN4,CDK7,CFTR,CDC42,MYL12B,MYL12A,CDK9,TMPO,LDLR,ACTA2,ALYREF,COX4I1,SSBP1,FOXP1,USP15,ESYT1,SNRNP70,SHC1,H2AC4,HDAC6,TLE1,DPP4,MSH6,H2BC14,PSMB10,FBXO25,VTA1,KPNA2,H3C1,SEPTIN7,PPP1R12A,BIRC5,PSMC3,NUPR1,CAPZA2,TFCP2,PIK3CA,AURKAIP1,ACTR1A,FBP1 |
| 1.211e-05 | -11.32 | EHD1 (EH domain containing 1) | protein interactions | 10938 | 148 | 66 | 19454 | 5460 |
CIAO1,RAB11A,MYC,RHOB,BRCA1,LAMTOR1,FAS,DNAJB6,EXOC8,AP2A1,OSGEP,PRKRA,RHOJ,TECR,CLDN4,SCP2D1,TOMM22,EHD3,STXBP1,CFTR,GTF3C4,EHD1,STX17,STAT6,ACTMAP,RAB5A,YTHDF1,STX7,FAM174A,VPS26A,ATG9A,LAMP2,API5,DRG2,SMAD4,MUL1,AGPAT1,HSPB1,PDCD10,EHBP1,HRAS,DNM2,RAB35,RAC2,PREP,AASDHPPT,PRNP,ARF6,WIF1,CAV1,CDC5L,ZBTB2,SNAP29,RAF1,HOXB1,PPP2R1A,PGGT1B,CCR1,STX12,EHD4,TRIM11,IGF1R,XPNPEP1,KRAS,PDE12,RIGI |
| 1.212e-05 | -11.32 | negative regulation of intracellular transport | biological process | GO:0032387 | 51 | 30 | 18204 | 5365 |
CD36,TXN,ARFIP1,MAP1B,CRYAB,ERLEC1,SUMO1,ADIPOQ,RAB23,SVIP,OS9,UBAC2,PCSK9,MIR185,CHP1,NUP153,UFM1,PKIA,UBE2G2,MIR17,PLN,SNX12,PKIG,ARHGAP1,MRLN,SUFU,CDK5,ANGPT1,DERL2,SNX3 |
| 1.222e-05 | -11.31 | FBL (fibrillarin) | protein interactions | 2091 | 620 | 222 | 19454 | 5460 |
SRP72,YTHDF2,EEF1A1,LBR,RPL15,NOC4L,RPS13,ARF4,OLA1,SMN1,NKRF,TCOF1,MPHOSPH10,PSMD7,MOV10,SPATS2L,BAK1,TOP1,MRPS23,PTPN1,KRR1,PWP2,CDK1,LMNA,MRPS34,METTL14,GRM2,RPL26L1,NOL7,RPS14,SNRPN,EDF1,EIF5B,FBXW7,RPL4,PIAS1,NHP2,POLDIP2,BRIX1,AATF,HELLS,RPA3,PNO1,SIRT7,PRKCB,SQSTM1,MTDH,ZNHIT3,RPL26,FBXO7,KPNA6,NDN,RPL13A,CCNF,EIF4A3,ENO1,PTEN,EZH2,EXOSC3,CHMP4C,RPS11,NAA15,RAF1,MAK16,G3BP1,TRIM37,S100A10,MRPS17,GTF3C3,SSRP1,RPS24,MRPS26,RPL23,CLPX,MAP3K14,NOP58,RPL7,DHX15,RPL9,RPL8,MRTO4,LARP4B,ARMCX3,TBC1D17,WDR77,NAP1L3,YTHDF1,NOP53,COIL,NKAPD1,UPF3B,NMRAL1,TXNL1,CCDC86,BRCA1,RPS5,LSM14B,NOP16,CUL3,PRPF31,RANBP6,PRRC2A,RPL19,ZMAT2,RPS9,RP9,RBM34,RNF8,NUPR1,STRBP,SRFBP1,IPO8,MRPL47,TP53,ZMYM4,IMP4,MEPCE,PHF1,RPL17,ABCE1,MRPS18B,RPL3,H2AC4,SNRNP70,RPS2,TAF9,KPNA1,TSNAX,RPL10A,COPS5,SPPL3,FZR1,DKC1,SURF6,GTF2B,SYNCRIP,RPL32,RAC2,RPA2,WWP1,UTP15,TRIM36,CDC42,WDR3,ZC3H15,RBM23,BANF1,PGK1,RNF113A,MECP2,SPOP,RC3H2,ZBTB38,ATP1A1,UBE2H,SMARCA5,RSL24D1,SRPK2,RPS3,EIF2S2,RBMX2,PHAX,MTA2,CSTPP1,RPL18,RPS23,TRMT1L,TOP3B,ARFGEF1,SOX2,RPS7,GXYLT2,KRAS,CHCHD2,VDAC1,RUVBL1,RPS4X,UTP25,RPL31,LSM14A,TOP2B,RUVBL2,CDC23,MGMT,MAGOH,DDX50,BAZ1B,WWP2,RPL6,XPO1,DDRGK1,LYAR,FUBP3,MAGED2,EED,MAP2K1,NUFIP2,PIH1D1,MTF1,PAFAH1B1,FXR2,UFL1,STAU1,MRPS7,CD40,DDX5,RAB5A,ATG3,FTSJ3,COP1,POLR1B,RCL1,MYC,PRMT6,RPL39,BTF3,MATR3,SNRNP40,PSMB6,RPL10,DLST,PRMT5 |
| 1.222e-05 | -11.31 | Formation of the ternary complex, and subsequently, the 43S complex | REACTOME pathways | R-HSA-72695 | 53 | 32 | 10285 | 3229 |
RPS5,RPS15,EIF1AX,RPS10,RPS28,RPS17,RPS26,RPS27L,RPS7,RPS23,RPS29,EIF2S1,RPS11,RPS4X,RPS12,RPS2,RPS27A,RPS9,RPS13,EIF3J,RPS20,RPSA,FAU,RPS16,RPS24,EIF3D,RPS3,EIF3G,EIF3E,EIF2S2,RPS14,EIF3K |
| 1.222e-05 | -11.31 | mRNA Splicing - Minor Pathway | REACTOME pathways | R-HSA-72165 | 53 | 32 | 10285 | 3229 |
SRSF1,LSM2,SRSF7,SRSF2,SF3B5,MIR636,POLR2C,SNRPD1,GTF2F1,SF3B4,POLR2I,DDX23,POLR2B,NCBP2,SNRPD3,SNRNP48,POLR2G,DDX42,SNRPE,TXNL4A,GTF2F2,SNRPB,POLR2F,SF3B6,SF3B1,ZMAT5,SNRPD2,SNRNP40,SNRPG,POLR2D,POLR2L,ZCRB1 |
| 1.232e-05 | -11.30 | NKRF (NFKB repressing factor) | protein interactions | 55922 | 234 | 96 | 19454 | 5460 |
PSPC1,CCNF,METAP2,EIF2AK2,ZNF330,PRKRA,FGFBP1,RPL13A,SMURF1,SRPK2,RPL7A,PPP1CC,HMOX2,RC3H2,UBE2H,RPA3,SIRT7,RNF113A,NPM3,DGCR8,RPL4,BCL6,CCL3,RPA2,HEXIM1,RPLP0,KRR1,RCHY1,PRR3,FZR1,CAND1,RPS16,CGAS,RBM42,SURF6,ZBTB2,MOV10,GRSF1,NFKB1,COPS5,CSNK2A1,CHCHD1,SNRNP70,RPS2,KPNA1,SNIP1,RPL23A,RPL3,DHX9,MEPCE,TP53,RPSA,AURKAIP1,HBP1,RPL37A,SNRNP40,RPL35,APEX1,RPL19,MYC,RAB11A,HNRNPC,CUL3,ZNF668,BRCA1,DCAF4,H1-1,DDX5,EP300,UFL1,STAU1,MTF1,BET1,RPL8,SRSF1,RPS10,LYAR,RPL7,DHX15,IFI16,WWP2,HNRNPA1,CPEB1,DDRGK1,DDX23,PEX3,DRG1,RPL31,SRSF7,RPS24,KRAS,H1-6,RAF1,E2F4,SOX2,JUN |
| 1.235e-05 | -11.30 | GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1) | protein interactions | 8729 | 439 | 164 | 19454 | 5460 |
STX6,DBT,CAV1,ST3GAL5,RPS27L,PRNP,CGAS,DERL2,CDK6,HRAS,AIFM1,EIF4E2,UBE2G2,USP15,SLC2A1,PSMD7,SHC1,ECD,PDE1A,CSNK2A1,HDAC6,CTNND1,ARF4,EIF3E,CAPZA1,GALNT2,KPNA2,RAB3B,RNF133,SEPTIN7,PPME1,MGARP,CLEC2B,MAP1LC3B,COMTD1,CHRM3,VKORC1L1,FERMT2,UBB,DYRK1A,SEC63,PDCD5,VIRMA,SRPK2,PSMC5,SEC61A1,WDR45,ODR4,CREB1,CCNF,CHRM4,CTTN,ZBTB33,XPOT,CDC73,TYROBP,IVNS1ABP,BRAP,FBXO7,USP14,CSK,RAB2A,PTPN11,NPM3,STK38,SQSTM1,DVL2,BAP1,RPA3,PRPF4,CDK1,RPA2,JUP,GOLGA5,KDELR2,SLC35E1,HCST,CD2AP,XBP1,CACYBP,EGLN3,HSP90AB1,FAM98A,ECHDC1,SNX2,CCAR2,SNX1,CORO1C,GJA1,RBM5,SWAP70,VCPIP1,YWHAB,PDAP1,ELP6,DRG2,YWHAG,YWHAH,P2RY10,DLK2,WDR11,ATG9A,FAM174A,RAB5C,PSMD12,AHCYL1,RPAP3,PDIA6,ZYX,SCYL2,ARGLU1,TMT1A,CCT8,RPS11,CSTPP1,JPT2,CRKL,STK16,CYB5B,PLS3,VPS33A,EZH2,ACTN4,B3GNT2,ARFGAP1,RAF1,TOP3B,NCKAP1,TAGLN2,RPL7L1,RPL35,ARF1,FAM91A1,EFHD2,FIS1,CCDC25,SCFD1,CHTOP,YWHAZ,FBXW11,BRCA1,PRPF31,JPT1,BAG3,SLC30A5,GPR17,RAB11A,CUL3,SFN,UNC45A,NPTN,HSCB,STAU1,TXNL1,RAB5A,DNAJC3,CD40,KLC2,EIF4B,PLAA,NPY2R,YIPF5,FAM234A,BET1 |
| 1.249e-05 | -11.29 | negative regulation of cell development | biological process | GO:0010721 | 269 | 112 | 18204 | 5365 |
CCL3,PRDX2,YWHAH,FRZB,LILRB1,TMEM176B,FOXP3,LDLR,FGL2,CCL11,GPR37L1,TLR4,THY1,GPR137,CDK6,BRINP1,TP53,DLX1,TLR3,ID4,SFRP1,IL6,TNFAIP6,MYC,SOCS5,RTN4,RUNX1,TSPO,PIK3R1,BTG2,NR2E1,IL4,IRF1,TCTA,SYT4,LILRB4,MIR146A,PSEN1,PTN,INHA,MIR21,IFNA2,MIR30B,TRIM11,IFNB1,PAX6,MIR137,FBXO7,RC3H2,MECP2,MIR181C,BMPR1A,B2M,VEGFA,CBFB,CAV3,UBASH3B,NF2,LHX2,PPP3CA,WNT7A,HMGB1,CDK5,SPP1,C1QC,IL1B,RFLNA,BCL6,HDAC6,TRIM46,FCGR2B,NOG,SEMA5A,FBXW7,DUSP10,DRD3,PROX1,ADIPOQ,TNF,IGF1,WEE2,CERS2,IL1A,NPR2,NKX6-2,CTNNB1,MT3,PAEP,MIR222,TNR,CTNNA1,F2,IL2,RNF10,MIR221,DICER1,SNAI2,PTHLH,CTDSP1,CTLA4,IFRD1,TRIB1,CARTPT,PTEN,NPPC,NRP1,GSK3A,TOB2,FGF13,RB1,TMEM176A,RGMA |
| 1.249e-05 | -11.29 | GPN3 (GPN-loop GTPase 3) | protein interactions | 51184 | 107 | 51 | 19454 | 5460 |
POLR3H,POLR2F,RMDN3,POLR3B,SCN2B,POLR2B,MED17,CUL3,LMO2,HTRA2,GTPBP2,POLR1B,PFDN2,BRCA1,FAS,HSCB,POLR1D,DAAM1,PIH1D1,MED31,WWP1,RPRD1B,CDK1,VAPB,SPINT2,POLR2L,RPRD1A,EGLN3,POLR2I,XPO1,LAMP3,FAM174A,WWP2,SIGLEC5,SKIC8,FAM168A,RPAP3,IMMP2L,PDRG1,DNAAF10,EPHA4,ASPM,RPAP2,CHRM3,MED9,COMTD1,POLR2D,POLR2G,POLR2C,SPSB3,SIGLECL1 |
| 1.251e-05 | -11.29 | H2AC4 (H2A clustered histone 4) | protein interactions | 8335 | 470 | 174 | 19454 | 5460 |
SMARCA5,H2BC9,ATP1A1,UNC79,LIG3,MACROH2A1,IDE,SPTBN1,GTF3C4,CD2AP,H2BC11,RPA2,HEXIM1,BAP1,PPP1R26,RNF113A,USP3,USP2,COPS5,GAPDH,TUBG1,NOL12,SYNCRIP,SSBP1,UBE2N,CAND1,SHPRH,BRMS1L,DKC1,STRBP,TP53,H2AX,ZMYM3,TFCP2,EXOC3,RNF8,DHX9,NEDD8,H3C1,CSE1L,MEPCE,H2BC14,RPL17,CREBBP,HNRNPC,HNRNPAB,CCT2,H1-10,FTSJ3,RBM27,H1-1,MIDEAS,DLST,PRMT5,USP16,PSMD4,RFC4,SNRPA,XRCC5,HSPA8,EP300,FXR2,UBE2D3,HNRNPA0,UFL1,GINS3,DDX50,RPL6,DNTTIP1,H2BC17,CDC23,DDX1,YWHAB,SNRPD3,RHOH,LYAR,HMG20A,SUPT5H,RPS7,TNPO2,PDHA1,SMARCB1,RTCB,H1-6,VDAC1,POLDIP3,CDC16,ZNF687,KPNA6,RACGAP1,PPP1CC,PELP1,EIF2AK2,PTEN,COPE,SCML2,VIRMA,TXNL4A,PIP5K1A,UBA52,ABHD5,CDK1,LMNA,METTL14,RPL26L1,PPM1G,SOD1,RPA3,H2BC12,GTF2I,BRIX1,UTP23,AATF,CXXC1,HDAC6,MPG,EXOC2,H2AZ1,KRR1,TES,EEF1A1,UBR7,ACTR2,RAD23B,SRP72,EHD4,H2AC25,RING1,HSD17B10,ANAPC11,RNF20,EIF3E,RFC5,RNF40,MCM4,BRCA1,ZCRB1,PARP2,TUBB,RFXAP,PRRC2A,H1-5,PPP1CB,APOBEC3C,ADGB,CCDC86,CFDP1,SKP1,HMGA1,HNRNPA1,WDR12,DDX23,HNRNPD,DNM2,PHB1,KRT8,HP1BP3,NOP58,SNX18,SPTAN1,CETN2,LRWD1,ACO1,EZH2,SNRPE,SART3,HNRNPA2B1,TRIM37,RPS27A,GTF3C3,MCM6,RFC2,RFC3,SSRP1 |
| 1.254e-05 | -11.29 | MRPL55 (mitochondrial ribosomal protein L55) | protein interactions | 128308 | 126 | 58 | 19454 | 5460 |
MRPL41,RPL4,MRPL40,GFM1,MRPS18A,MTRES1,RPL27A,RBMS2,MRPL12,MRPL10,RPL35,RPL13A,MRPL23,RPL10,RPL19,TACO1,MRPL53,MRPL13,CHORDC1,PMPCA,AUH,MTG2,MYC,PHKA1,TOMM40,RPL17,FLOT1,HNRNPDL,IMMP2L,MEPCE,SRSF4,MRPL52,SRSF7,HINT2,RPL23A,RPS23,MRPL51,ILF2,MRPL47,MRPL11,RAF1,TOP3B,METTL15,MRPL50,FZR1,MALSU1,SSBP1,MRPS9,FAHD1,GATD3,SNRNP70,MRPL18,RHOG,HNRNPD,MRPS26,RAB5C,MTRF1,MRPL9 |
| 1.254e-05 | -11.29 | TLCD4 (TLC domain containing 4) | protein interactions | 148534 | 99 | 48 | 19454 | 5460 |
COX4I1,COMT,FA2H,TNFSF18,TMEM237,OPRL1,SYNJ2BP,PMP22,TMEM19,EMC6,SLC41A1,SCAMP5,FXYD6,UPK1A,ADGRE2,SFXN1,CLEC7A,ERG28,SLC7A14,TMEM60,YIPF4,YIPF3,CRELD1,STX12,CDIPT,DPEP1,TMEM229B,TVP23B,MYG1,VEZT,KDSR,GJB2,CYP4F22,REEP6,CXCR4,ORMDL1,TSPAN15,NINJ1,GOSR2,SEC22B,CCDC167,SEC22A,CFTR,CTXN3,TMEM115,TIMM23,SYNDIG1,FDFT1 |
| 1.268e-05 | -11.28 | ACBD3 (acyl-CoA binding domain containing 3) | protein interactions | 64746 | 240 | 98 | 19454 | 5460 |
NTRK2,IGF1R,AKAP12,CACNG3,KPNA2,RAB3B,SOCS2,FKBP8,MTCH2,TP53,ACTR1A,FURIN,PSMC3,CD274,PTPN1,HSD17B11,RAC2,DNAJC1,ARF6,EPHB6,LMAN1,TMPO,STX6,CAV1,SLC25A46,FAM20C,LAMP3,GTF2E1,COPS5,SLC35A1,USP15,STYK1,BAP1,SYVN1,DERL1,RAB9A,HMGB1,SMC4,TOMM20,CDC42,ST7,SSR1,FGFR1,METTL14,ACACA,CCNF,GANAB,VIRMA,RAB2A,GORASP2,EPHA2,NRP1,TMT1A,PSMA1,KRAS,EPHA4,G3BP1,MCM6,ERRFI1,ARFGEF1,DNAJC25,TULP3,STIM1,RPN1,RAB4A,PTRH2,RAB35,GJA1,RHOH,NUP35,ATG9A,LAMP2,RAB5C,DDX23,WDR12,RHOG,PMAIP1,STK26,RAB5A,SRSF2,PXMP2,STX7,UNC45A,BET1,OTULINL,RND2,SEC62,LMBR1L,RMDN3,SEC61B,MATR3,CUL3,RAB11A,PSMD1,MCM4,LAMTOR1,NTRK3,FIS1 |
| 1.268e-05 | -11.28 | ANXA1 (annexin A1) | protein interactions | 301 | 240 | 98 | 19454 | 5460 |
ERG28,EMC2,HINT1,FAF1,SOD2,RNF8,PIK3CA,DDX39A,PGM1,TP53,CGAS,CD4,HRAS,HDAC6,GAPDH,MOV10,CRYZ,FBXW7,RNF34,PRDX6,SOD1,RPA3,INPPL1,BAP1,PML,SIRT7,SHOC2,WTAP,RPA2,CZIB,STX17,CFTR,SRC,UBE2I,ENO1,EPHA2,CDC73,STK11,FXN,UBE2H,LGALS8,MTPN,TFG,GUK1,G3BP1,KRAS,TRIM37,UBE3A,UCP2,KLHL23,CCR1,MOB3C,EZH2,PIR,CHMP4C,NGB,SOX2,ISG15,DLG3,PPIA,CCT7,OCRL,SUMO2,FAHD1,KRT8,CBFB,ANXA4,MGMT,HSPB1,UBE2D1,PPM1B,AGR2,HNRNPA1,STK4,HMGA1,MAP1S,PTDSS1,EMC1,STAU1,GPC1,HSPA8,PTRHD1,PEBP1,FKBP1A,ANXA7,WDR77,LRIF1,ESR2,AKR1C2,RNF208,BRCA1,RPS6KA4,YWHAZ,S100A11,BAG3,MYC,PMPCA,RAB11A |
| 1.275e-05 | -11.27 | ABAT (4-aminobutyrate aminotransferase) | protein interactions | 18 | 73 | 38 | 19454 | 5460 |
BAG3,ACP6,HMGCS1,SEC22C,CFL2,CFL1,SORD,MDH1,PYURF,TST,ENO1,FAHD1,AKR1B1,GATD3,SYBU,DSTN,SERINC1,GLTP,CMBL,LDHA,HNRNPL,AKR1C2,FAH,ESD,ETFB,LGR4,PGM1,LDHAL6B,FKBP1A,RAD23B,SOD2,EPHX1,NANP,PEBP1,HINT2,ETFA,HSPE1,GPM6A |
| 1.280e-05 | -11.27 | CCDC8 (coiled-coil domain containing 8) | protein interactions | 83987 | 652 | 232 | 19454 | 5460 |
DOK6,SYNCRIP,CAND1,FZR1,TMPO,ZNF24,GPRASP2,CSNK2A1,GAPDH,TUBG1,SMCHD1,RPS2,FAM222A,RPL10A,MAP4,PALM2AKAP2,MAP1B,RPL3,DHX9,KPNA2,CSE1L,SRPRB,FKBP8,ATP5PB,TP53,EXOC3,NEFL,CAPZA2,UQCRC2,RPS3,LIG3,MRPS28,RALA,SRC,DYRK1A,RAB2A,SMARCA5,RPL7A,DNAJC5,MRPS16,IGF2BP1,ATP1A1,UBE2H,RAB9A,MARS1,HSPA5,CDC42,AGO1,RPA2,ZNF326,ARL15,PRKCA,RAB35,EIF2S1,HNRNPL,TCP1,RHOH,ANKRA2,HSP90AB1,CCT7,BAZ1B,DDX50,RAB5C,RPL6,YWHAH,YWHAG,XPO1,CTNNB1,CDC23,DRG1,S100B,PABPC1,CCT8,ABCF1,MYO1B,RUVBL2,EFNB1,EWSR1,PDIA6,RTCB,CHCHD2,HNRNPF,KRAS,RUVBL1,RPS4X,RPL28,POLDIP3,GLE1,UCK2,PNMA2,RND3,RPL18,RRAS2,FAM83B,SMU1,MATR3,ATP5F1B,STAT1,PSMD1,MLF2,CKB,CCT2,LAMTOR1,CHTOP,SERPINH1,SPECC1L,XRCC5,SF3B1,DDX5,UFL1,TRA2B,HNRNPA0,STAU1,EEF1G,PACSIN3,ZC3H14,AIFM1,H2AZ1,ARF6,ATP5PD,NCBP2,NOP9,CAV1,ATP1B1,LRRC40,EIF5A2,RAB1A,EHD4,SFXN1,NTRK2,SNAP23,EMC2,HUWE1,CTNND1,GALNT2,TBK1,EEF1A1,ILF2,VAMP3,CCNF,FBLN5,CTNNA1,ENO1,ALB,F11R,LDHA,TMOD3,RAB14,RPL13A,RHOJ,GNAI2,RPL22,EMILIN1,ATP5F1A,CSGALNACT2,TUFM,NONO,NRP1,HELLS,NCDN,DVL2,RHOU,MTDH,LARGE1,SMC4,CPSF4,RPS14,SEC22B,CCL3,CNP,CDK1,JUP,LMNA,HSP90B1,SLC12A2,HNRNPH3,RPLP0,RARS1,RPL8,RPL9,PHB1,GJA1,NOP58,CCAR2,RPL7,SNX2,ATXN10,EGLN3,PDIA3,PSMD3,STOML2,HNRNPA1,EIF3D,RHOG,RB1CC1,DICER1,HSPD1,RBBP7,LASP1,G3BP1,LAMB2,ETFA,MCM6,FLOT1,RFC3,RFC2,PPP2R1A,ACTN4,RPS11,RBBP4,CHCHD3,SNRPB2,GNB1,RFC5,MCM4,MCM3,RHOB,LMNB1,YWHAZ,FBXW4,EXD2,HADHA,RP2,STX7,PSMC1,SKP1,PGRMC1,RND2,USP39,ADNP,SLC25A3,ARCN1 |
| 1.284e-05 | -11.26 | DRG2 (developmentally regulated GTP binding protein 2) | protein interactions | 1819 | 58 | 32 | 19454 | 5460 |
NT5C2,API5,XPO1,YWHAH,DHPS,HSPA14,RSBN1L,NAB2,PHF21A,RWDD1,EIF4A3,TNFRSF1B,CCNF,RHOJ,TRIM54,DNAJC1,EHD1,RAF1,SCLT1,ACADSB,DNAJC2,EZH2,RPA2,TMX3,EP300,HSPA8,RPA3,SNIP1,SKP1,TOLLIP,KDM1A,HSCB |
| 1.284e-05 | -11.26 | IFIT2 (interferon induced protein with tetratricopeptide repeats 2) | protein interactions | 3433 | 58 | 32 | 19454 | 5460 |
RAB11B,SNRPB2,LMAN1,DBT,CGAS,TUBB,SNRPD3,SNRPA1,MATR3,HNRNPL,RPLP1,TES,SNRPD2,SNRPD1,HOMER3,HNRNPD,SNRNP70,SNRPB,HNRNPA1,HNRNPAB,WWP2,IFI16,HNRNPDL,RIGI,HNRNPA2B1,PABPC1,RPL31,SNRPA,SNRPE,ILF2,LMNA,ISG15 |
| 1.284e-05 | -11.26 | PPCS (phosphopantothenoylcysteine synthetase) | protein interactions | 79717 | 58 | 32 | 19454 | 5460 |
TCOF1,RPA3,SNAPC1,PSMD12,CTNNBL1,KRAS,GXYLT2,RPE,CDK7,DLG3,CCR1,USE1,RPA2,BPIFB1,VPS33A,LMNA,MED23,COPS2,PRMT5,POLR3B,SPRED2,RPL10,IDE,PSMB6,RPL35,PSMD6,KCTD10,HP,PNPLA4,CDC16,RIT1,LACRT |
| 1.285e-05 | -11.26 | positive regulation of interleukin-10 production | biological process | GO:0032733 | 42 | 26 | 18204 | 5365 |
IL4,CD274,HSPD1,TLR2,IL20RB,CD83,SASH3,HMGB1,SYK,TLR9,CD40LG,TLR4,PYCARD,IRF4,ISG15,CD46,IL12B,XCL1,RAD21,IL13,MIR145,CLEC7A,CD28,IL6,TUSC2,IL23A |
| 1.285e-05 | -11.26 | negative regulation of vascular associated smooth muscle cell proliferation | biological process | GO:1904706 | 42 | 26 | 18204 | 5365 |
IL10,CDKN1A,MIR339,MIR1298,MIR185,MIR223,MIR137,PTEN,ADIPOQ,MIR638,MIR15A,MEF2C,MIR34A,SOD2,MIR424,MIR1-1,PDCD4,TGFB3,APLN,MIR214,CDKN1B,MIR182,MIR140,MIR96,PPARG,MIR503 |
| 1.285e-05 | -11.26 | regulation of defense response to virus by host | biological process | GO:0050691 | 42 | 26 | 18204 | 5365 |
PYCARD,HSP90AA1,APOBEC3F,TOMM70,MICB,LILRB1,IL1B,PQBP1,DHX9,TRIM22,SELENOK,TRIM6,APOBEC3G,CGAS,IL23A,TNFAIP3,TRAF3IP2,IL12B,MUL1,TRIM44,MAVS,STAT1,SIN3A,RIGI,IL15,NT5C2 |
| 1.311e-05 | -11.24 | MXRA7 (matrix remodeling associated 7) | protein interactions | 439921 | 68 | 36 | 19454 | 5460 |
CCDC47,TOP3B,SEC62,OTULINL,DNAJC25,ST7,RPN1,STIM1,MAP2K1,RAB4A,SSR1,CYB5B,TMT1A,HSPA8,RAB9A,DERL1,RAB5A,RAB3B,STAU1,STX7,FKBP8,MOV10,RAB11A,RHOG,ESYT1,LMNB1,RAB35,PTPN1,GUCY1B1,HSD17B11,CYB5A,SEC61B,DNAJC1,TMPO,LMAN1,SEC63 |
| 1.311e-05 | -11.24 | ABCC2 (ATP binding cassette subfamily C member 2) | protein interactions | 1244 | 68 | 36 | 19454 | 5460 |
EEF1A1,SOX2,MRPL10,TOMM22,NDUFA2,JUP,VAMP2,PICALM,SSR1,PTRH2,NHERF1,TOMM20,HNRNPDL,CHCHD2,KRAS,MRPL57,SLC30A5,NFKB1,SYNJ2BP,MRPS35,MRPS26,AP2M1,MRPS28,PRR3,AZIN1,MCPH1,RAB31,S1PR4,NDUFS8,TOMM70,RAB11B,MRPL24,B4GAT1,RAB14,MRPL23,LGALS3 |
| 1.315e-05 | -11.24 | VPS51 (VPS51 subunit of GARP complex) | protein interactions | 738 | 168 | 73 | 19454 | 5460 |
CTBP1,RPA2,GOLGA5,GIT2,SCLT1,VPS54,NUP62,ATG16L1,BET1,CDC42,CDKN1A,BORCS6,NUDT3,NPTN,OIP5,STX7,RPA3,VIPR1,RAB9A,EP300,RAB5A,LAMTOR1,RHOB,CHRAC1,CCHCR1,IGF2BP1,RAB2A,RAB11A,AR,SLC30A5,RHOJ,LMBR1L,CD79B,ARF1,LURAP1,B4GALT1,PHF21A,TFRC,VPS33A,EZH2,AQP3,RAB4A,TRAPPC13,SNAP29,MGARP,TNFSF8,KRAS,RAB1A,TFPT,TMT1A,SLC39A3,RHOG,TRAPPC2L,CDK12,LAMP2,ATG9A,KXD1,FAM174A,EDEM1,LAMP3,EXOC1,RAB1B,ARF6,CAND1,RHOH,STX6,CDC5L,HMG20A,RPRD1A,HRAS,RAB35,AIFM1,GJA1 |
| 1.315e-05 | -11.24 | GAB1 (GRB2 associated binding protein 1) | protein interactions | 2549 | 168 | 73 | 19454 | 5460 |
RHOG,SHC1,NCK1,STYK1,YWHAB,PIK3R1,MAPK4,YWHAG,FCGR2B,YWHAH,SHC3,LAT2,TRIM15,EGLN3,STX6,DIRAS3,CAV1,RAB35,HRAS,ITK,GJA1,GRAP2,GNAI3,CRKL,SOCS3,EPHA4,KRAS,RPS27A,FLOT1,PABPC1,PIK3CG,JAK1,IGF1R,NTRK2,LAMTOR1,SYP,YWHAZ,RHOB,EPHA2,NTRK3,CSK,AKT1,PTPN11,RAB11A,SFN,PIK3R3,TUFM,DNAJC5,BAG3,MAP3K3,YES1,RHOJ,ROCK1,MAD2L1,SRC,APEX1,VIRMA,GAB1,SLA2,GSK3A,CALML5,JUP,VAV2,FGFR1,MET,SYK,HSH2D,PIK3R2,STX7,STAP1,RHOU,INPPL1,NUBP2 |
| 1.317e-05 | -11.24 | REEP2 (receptor accessory protein 2) | protein interactions | 51308 | 63 | 34 | 19454 | 5460 |
TMX2,ATP5PF,RABAC1,DERL1,YIF1A,NUP50,TMEM60,SFT2D2,SEC62,OTULINL,ST7,TMEM31,SSR1,HSD17B11,REEP3,COPE,REEP4,SLC25A46,TMEM208,CAV3,YWHAG,YWHAH,H2BC9,ORMDL3,TMBIM6,TMEM42,MUL1,YWHAZ,LMNB1,KCNIP2,ENDOD1,CYP4F22,C2CD2L,YWHAB |
| 1.317e-05 | -11.24 | ME1 (malic enzyme 1) | protein interactions | 4199 | 63 | 34 | 19454 | 5460 |
TOM1,PPWD1,VTA1,UGDH,BAP1,DDX39B,RPA3,GPX4,OAZ3,RING1,FGFR1,STX17,RPA2,VAC14,FTH1,FCF1,FBXO22,NMI,CTTN,CCNF,LCMT1,MSN,ARPP19,GTF2A1,PREP,AGR2,GSTK1,CUL3,CST3,NFYA,AR,GORASP2,CTNNB1,OTUD7B |
| 1.317e-05 | -11.24 | OAS3 (2'-5'-oligoadenylate synthetase 3) | protein interactions | 4940 | 63 | 34 | 19454 | 5460 |
HSPA8,MAVS,PPM1G,RFC4,PML,G3BP2,FBXW7,NOP53,CNP,H1-5,RAF1,FBP1,E2F4,GPD2,LLPH,EXOSC3,CHMP1A,RPLP1,ARF1,ESR2,VIRMA,CDC5L,ZNF622,IFRD2,TOP1,LYAR,HDAC6,RPL39,MYC,PRPF19,NOP16,SPOP,FTSJ3,CCDC22 |
| 1.328e-05 | -11.23 | RAB11FIP1 (RAB11 family interacting protein 1) | protein interactions | 80223 | 118 | 55 | 19454 | 5460 |
CDC42,RND2,NOTCH2,ATG16L1,FGFR1,RPA2,RAB9A,DDX5,RAB5A,FLCN,RHOU,RPA3,STX7,AR,DNAJC5,PPP1CC,RAB11A,SFN,NTRK3,YWHAZ,RHOB,LAMTOR1,ESR2,VIRMA,RHOJ,TAX1BP1,RAB14,RAB4A,SCHIP1,TRIM21,S100B,CTSC,RNF26,TFG,FLOT1,TOM1,KRAS,XPO1,YWHAG,LAMP3,YWHAH,LAMP2,ATG9A,YWHAB,BRD3,RASSF8,RHOG,RAC2,RNF128,RAB35,CAV1,RAB11B,STX6,EPHB6,RHOH |
| 1.333e-05 | -11.23 | regulation of endocytosis | biological process | GO:0030100 | 295 | 121 | 18204 | 5365 |
CLEC7A,CSK,SYNJ2BP,HPCA,ROCK1,CDC42,LRRTM1,LPAR1,CD47,SDCBP,FCER1G,IFNG,NLGN1,RAB4A,FGR,ARF1,IL2RB,MIR185,CLIP3,CBLL1,DLG4,HNRNPK,FLOT1,SNAP91,VAC14,MTMR2,ITGAV,ANGPT1,SCAMP5,HSPA8,LILRB1,APLN,CALY,SRC,SGIP1,PTPN1,VEGFA,CD36,B2M,CAV3,AP2M1,IL15,SNX17,CAV1,LYAR,LGALS3,APOC2,AP2S1,SYT4,EHD4,PSEN1,SFRP4,AP2A1,OPHN1,MKLN1,IL4,SNX3,FCGR2A,GH1,RALA,IL2RG,LRRTM2,TF,H1-1,ADIPOQ,ACTB,CD63,PACSIN3,PIP4P2,CALR,PPT1,FCN2,CDH13,MIR92B,FCGR2B,SNX33,ITGA2,GREM1,STAP1,CCDC32,PYCARD,MBL2,PPP3CA,WASL,ARFGAP1,HMGB1,SYK,CLU,MIR205,VPS28,DKK1,HFE,RAB31,IL15RA,RAB27A,FCGR1A,CCL2,TSG101,ATAD1,CD151,PLA2G5,ATG3,RIT2,PCSK9,NR1H2,CCL19,SFTPD,PICK1,ARF6,PICALM,PLSCR1,SOD1,MIR17,MIR20A,SNX12,CCL21,CBL,TBC1D5,MIR183,CD14,TLR2 |
| 1.348e-05 | -11.21 | MRPL30 (mitochondrial ribosomal protein L30) | protein interactions | 51263 | 154 | 68 | 19454 | 5460 |
RPL10,RPL19,MRPL23,RPL35,RPL13A,RPS9,MRPL13,ZNF22,MRPL53,MCAT,UBE2H,FBXW11,MRPL16,RPL26,TUFM,MYC,PMPCA,CDKN2D,NHP2,MRPL20,MRPL17,MRPL41,FBXW7,MRPL57,MRPL40,MRPL34,GFM1,NGRN,EXD2,RPL26L1,SLC25A3,MTRES1,MRPS18A,MRPL10,PLP2,RBMS2,MRPL12,RPL27A,MALSU1,MRPL24,MRPL50,SYNCRIP,ALYREF,MRPS26,MRPL18,RHOG,SNRNP70,MRPL9,TRA2A,MTRF1,RPL6,MRPS17,MRPL22,RPL17,KRAS,GJB1,HECTD3,MRPL52,S100B,MRPL33,MRPL49,MRPL51,MAP2K3,METTL15,IKZF5,MARCKSL1,MRPL47,MRPL11 |
| 1.352e-05 | -11.21 | CYB5A (cytochrome b5 type A) | protein interactions | 1528 | 129 | 59 | 19454 | 5460 |
CCR1,SOD2,SLC25A24,RPN1,STIM1,SOX2,CCDC47,MTCH2,KRAS,ARHGAP15,CYBRD1,TMT1A,CYP2D6,AGPAT1,POR,FAM241A,EMC4,COX5A,ISYNA1,ATP5PD,WIF1,NUP35,HNRNPL,SNX2,HSD17B11,SRPRA,PHB1,NDUFA5,COX6C,ATP5PO,LMNA,SSR1,SEC62,OTULINL,ST7,SEC22B,PGRMC1,HSPA5,ATP6V1G1,PHB2,RER1,SYVN1,DERL1,RTN4,AKAP1,TMX2,CYP17A1,FYTTD1,FAS,LAMTOR1,CYP1A1,ENDOD1,OST4,HSPA14,TAB1,SEC61B,GNG12,KCNMB1,CYB5R3 |
| 1.355e-05 | -11.21 | regulation of nitric oxide biosynthetic process | biological process | GO:0045428 | 63 | 35 | 18204 | 5365 |
TSPO,MIR99B,NOS1AP,CLU,RGN,DDAH1,GCHFR,AKT1,MIR132,IL1B,KLF4,DDAH2,HSP90AA1,TLR6,MIR212,HBB,TLR4,ATP2B4,NOSIP,DYNLL1,CAV1,JAK2,CD47,TICAM1,TNF,SMAD3,ACP5,IFNG,IL10,ROCK2,CD36,CX3CR1,CLEC7A,HSP90AB1,SOD2 |
| 1.365e-05 | -11.20 | cellular response to oxygen levels | biological process | GO:0071453 | 161 | 73 | 18204 | 5365 |
NDNF,KCND2,ATP6V1G1,AIFM1,AKT1,NOP53,SRC,STUB1,FAM162A,LMNA,HILPDA,MGARP,MIR140,ATF4,CLCA1,NKX3-1,PHB2,TP53,NDUFS2,LPAR1,MDM2,STC1,MIR106B,MIEF1,EGLN3,ACAA2,MT3,MIR34A,KCNMB1,SFRP1,MIR126,MYC,RGCC,HP1BP3,NDP,CBL,FAS,SUV39H1,ERO1A,TERC,MIR20A,CDKN1B,MIR214,MIR17,CPEB1,ATG7,MIR146A,CCNA2,PPARG,PICK1,BECN1,PGK1,SLC29A1,AQP3,GAD2,FOS,NFE2L2,ATP6V1A,CAV1,NGB,MSTN,MIR448,BNIP3L,BAD,EGLN2,ADO,PRKCE,VEGFA,MAP1LC3A,TERT,MIR210,PMAIP1,TMEM199 |
| 1.372e-05 | -11.20 | leukocyte activation | biological process | GO:0045321 | 599 | 224 | 18204 | 5365 |
CEBPG,CD1C,TLR2,TRAF6,CD2AP,CD38,GJA1,SNAP23,RHOH,NHEJ1,CCL19,AIF1,IRF4,DPP4,IL2RA,VAMP2,SLC25A5,GPR89A,TBC1D10C,RAG1,KCNJ8,IL15RA,CD40,BCL6,SYK,CD1D,CLU,TOP2B,HMGB1,BATF,STK11,AGER,PYCARD,FCGR2B,PKNOX1,ITGB8,IL10,RBPJ,CX3CL1,SMAD3,LMBR1L,TNF,CD2,CMTM7,PHB1,SELENOK,VAMP7,MRGPRX2,CX3CR1,TUSC2,GPAM,TESPA1,PRKCQ,SLA2,TNFAIP8L2,IRF1,PIK3R2,CD3G,HELLS,PIK3R1,TPD52,NBN,CD247,PTGER4,JAML,LIPA,GAPT,MIR181C,EGR1,TICAM1,PTGDS,FBXO7,IL15,TLR1,EXOSC3,CHRNB2,EZH2,IL7,ITK,NCSTN,B2M,IL23A,KDELR1,IL18,PRDX2,NKAP,PRDX1,TLR4,LEP,LRRC8A,CD40LG,CDK6,PIK3CG,FGL2,DCLRE1C,PHB2,MICB,TP53,IFNG,IDO1,ICAM1,CXCL8,IL13,SLC39A7,CAMP,LEPR,AZI2,IL21,CLEC7A,KIT,CBL,NDFIP1,CCL21,TOLLIP,LAT2,MSN,IGBP1,DLG1,TMEM229B,DNAJB9,MSH6,EFNB1,LTBR,TGFBR2,IL2,IFI35,SKAP2,BST2,FKBP1A,JAK2,CD151,RAB27A,LCP1,CPLX2,PRKCB,PRKCE,HDAC5,CHGA,IRF8,FOSL2,SYVN1,RABL3,VAMP8,AKAP17A,PTPN22,PPP3CA,SLAMF9,RPL22,TNFSF18,STAT6,RNF8,CCR7,TLR6,NCR3,CCR6,IFNA13,KARS1,PIK3R3,NOTCH2,EP300,CCND3,IL2RG,TOX,NCK1,TMEM106A,BAK1,RAB29,HYAL2,CTNNB1,ALKBH5,JAK1,IL4,PSMB11,MYD88,PSMB10,EMP2,IL20RB,TLR9,IFNK,PSEN1,CD81,CD4,IFNA2,PDP2,LCP2,LILRA2,WNT10B,NMI,RC3H2,SOCS3,TYROBP,IFNB1,ST3GAL1,MEF2C,CD80,CBFB,CD28,SWAP70,FKBP1B,LILRB1,HSPD1,FOXP3,CD83,CCL3,SASH3,CD79B,PELI1,TNFSF8,IFNGR1,NFIL3,CSF2,IL12B,FCER1G,TLR3,ITM2A,CCL5,STOML2,FOXP1,CD86,IFNA10,IL6,RSAD2,BAX,TRAF3IP2 |
| 1.383e-05 | -11.19 | SEC16A (SEC16 homolog A, endoplasmic reticulum export factor) | protein interactions | 9919 | 409 | 154 | 19454 | 5460 |
CNOT2,SAV1,ATG7,YWHAG,HNRNPA1,XPO1,YWHAH,HSPB8,CTNNB1,IKBKB,RNF152,STAMBPL1,RB1CC1,HSPB1,CBFB,FUBP3,MAP1LC3A,GJA1,TSG101,KRT8,CCAR2,EGLN3,COX14,NUP35,B3GNT2,CSNK1E,TOP3B,RAF1,TUBA1A,ISG15,SOX2,TRAF2,RPN1,STIM1,PDHA1,PTRH2,CHMP4C,HDAC11,MOB3C,KLHL12,SCYL2,ZYX,HNRNPA2B1,TMT1A,PSMA1,TRIM37,SAR1B,MYC,RAB11A,CUL3,BTF3,BAG3,FAM83A,MYO6,DCAF4,BRCA1,PFDN2,ILK,MIDEAS,FAM83B,PHF21A,SEC61B,MTM1,TRIM29,AIPL1,PRRC2A,WDR77,TOMM22,BET1,SEC62,PPP1CB,CNPY3,DET1,NEK7,MED23,CSNK1A1,PIH1D1,P4HA2,RAB5A,ARHGEF39,PXMP2,DPP4,SLC25A46,LAMP3,HDAC6,TUBG1,SHC1,DNAJC7,AKAP8L,ETV6,PTPN1,CD274,AIFM1,HSD17B11,TES,SEC23A,CAND1,TMPO,STX6,KLF9,TBK1,TNRC6C,EGR2,AURKAIP1,CDK8,TFRC,CAMK1,NEFL,CAPZA2,GARRE1,CLPB,HNRNPK,DNAAF10,CNOT6L,CIAO1,CEP85,SEC13,AR,RC3H2,ZBTB38,UHMK1,AP2A1,MAPRE1,UBE2H,CCNF,SMAP2,GSK3A,CTSB,MGST3,DYRK1A,VIRMA,GABRA1,CDK7,ST7,CFTR,RPA2,LMNA,P3H1,PICALM,SSR1,HNRNPH3,BAP1,RPA3,PML,SIRT7,ZKSCAN1,DERL1,RAB9A,SQSTM1,RNF113A,KDM1A,HDAC3,STK38,FBXW7 |
| 1.392e-05 | -11.18 | NDUFB3 (NADH:ubiquinone oxidoreductase subunit B3) | protein interactions | 4709 | 94 | 46 | 19454 | 5460 |
VAPB,COX6C,NDUFA5,NDUFAB1,LPAR1,NDUFS2,HSCB,NDUFC2,EMP3,TACR1,SAYSD1,OPRM1,GPR17,NDUFB10,NDUFB6,NDUFB7,KDSR,CSGALNACT2,PARL,NDUFAF4,DPEP1,PRSS8,AQP3,NDUFS6,NDUFS3,GPR34,CRELD1,NDUFA12,NDUFA2,MGARP,YIPF3,DNAJC30,NDUFA4,NDUFB5,NDUFB8,P2RY10,NDUFV2,CCR6,WIF1,OPRL1,NDUFS8,NDUFB4,COX4I1,NDUFA1,CYB5A,FUT1 |
| 1.392e-05 | -11.18 | TANC1 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1) | protein interactions | 85461 | 94 | 46 | 19454 | 5460 |
AGAP1,FGFR1,RPA2,TRIM52,SQSTM1,HSPA8,DVL2,RPA3,MAPRE1,FBXW11,YWHAZ,BICD2,DNAJC5,SFN,MYC,DYRK1A,VIRMA,HOMER1,ACTB,RHOJ,TRIM24,RMDN3,GSK3A,DLG4,GRIA1,CASK,TOP3B,PTGES3,FKBP8,FLOT1,KRAS,DLG1,ZYX,YWHAB,STYK1,RHOG,CTNNB1,YWHAG,YWHAH,TAX1BP3,MOV10,SPTAN1,HNRNPL,INA,GJA1,RAB35 |
| 1.392e-05 | -11.18 | KDM2A (lysine demethylase 2A) | protein interactions | 22992 | 94 | 46 | 19454 | 5460 |
CREBBP,MYC,RPL7A,CUL3,H1-10,ENO1,ZNF330,MACROH2A1,SNRNP40,CBX5,MAD2L1,ESR2,VIRMA,PSMB3,CCND1,FBXL19,LMNA,RTF2,FOS,EP300,PPP1R2,FBXW7,STAU1,SKP1,BCL6,RAB5C,DPY30,MPG,BECN1,RPRD1A,RPL8,SMAD3,FBXO32,UBE2G2,EED,RPLP2,RB1,HNRNPL,H2AX,CBX3,RBPJ,NUPR1,ACTR1B,FHL3,KRAS,H3C1 |
| 1.397e-05 | -11.18 | MRPL37 (mitochondrial ribosomal protein L37) | protein interactions | 51253 | 220 | 91 | 19454 | 5460 |
UBE2H,MRPL16,TUFM,AUH,MTG2,CUL3,PMPCA,RPL19,VIRMA,RPL10,MRPS21,MRPL23,RPL13A,MRPS28,MRPL13,UQCRC2,MRPL53,TACO1,CCNF,ENO1,CCDC90B,MTRES1,CYC1,MRPS18A,RPA2,NDUFAB1,MRPL10,DHRS4,KLF12,MRPL12,RBMS2,MRPL20,DNLZ,ABCC2,MRPL17,HSCB,EMC1,MRPL40,MRPL41,MRPL57,PGK1,MRPL34,GFM1,NGRN,RPA3,EXD2,MRPS26,RHOG,MRPL18,CHCHD1,TMEM70,HNRNPA1,MRPL9,MTRF1,MOV10,GRSF1,STOML2,ATP5MG,EGLN3,MALSU1,MRPL24,RMND1,KCTD10,MRPL50,GATD3,SSBP1,FBXO32,COX4I1,GFM2,MRPL33,MRPL51,MRPL49,PDHA1,FAF2,AURKAIP1,METTL15,RAF1,MRPL11,MTCH2,MRPL47,MRPL22,FASTKD5,MEPCE,IMMP2L,SMN1,KRAS,HAPSTR1,HINT2,COX8A,MRPL52,HSPD1 |
| 1.399e-05 | -11.18 | Diseases of Immune System | REACTOME pathways | R-HSA-5260271 | 24 | 18 | 10285 | 3229 |
TLR5,LY96,NFKB1,TICAM1,IRAK4,TLR10,TLR4,TLR3,IKBKB,CD36,TLR2,NFKBIB,TLR6,MYD88,NFKBIA,TLR1,CD14,TIRAP |
| 1.399e-05 | -11.18 | Diseases associated with the TLR signaling cascade | REACTOME pathways | R-HSA-5602358 | 24 | 18 | 10285 | 3229 |
CD14,TIRAP,TLR1,NFKBIA,MYD88,TLR6,NFKBIB,IKBKB,TLR2,CD36,TLR3,TLR4,TLR10,IRAK4,TICAM1,NFKB1,LY96,TLR5 |
| 1.412e-05 | -11.17 | PPP2R2A (protein phosphatase 2 regulatory subunit Balpha) | protein interactions | 5520 | 276 | 110 | 19454 | 5460 |
THUMPD1,RPA3,DVL2,DDX46,SNAPC1,RNF113A,DERL1,HMGB1,SMC4,HSPA5,ATG16L1,PSMC4,CFTR,CDC42,RPA2,ACACA,UBE2M,ZNF574,CCNF,PSMC5,ADRM1,NDN,DAPK1,DUSP10,VIRMA,SMURF1,AR,UBE2H,RBM7,ZBTB38,TFPT,NOSIP,ABCE1,KPNA2,SERTAD1,DUSP19,VTA1,RPS13,CCT5,PSMC3,PPME1,PPP4C,FZR1,FOXC2,RBM17,GAPDH,SHC1,KIAA1143,FOS,RPS28,SERTAD2,HSPA8,HDAC5,STAU1,UFL1,PPP2R2C,CMAS,PSMC1,FBXO42,PTAR1,SYK,DET1,IER2,FOXS1,PIH1D1,PELO,PRMT5,SNRPD2,SMU1,RBBP4,PSMD6,MATR3,TCEAL1,RRN3,CUL3,GRB10,CREBBP,BTF3,PSMD1,DCAF4,CCT2,MED10,FAM107A,COP1,CCT8,RBBP7,PSMD12,UBE2A,RAF1,PPP2R1A,MOB3C,RPS11,PPP2CB,FABP5,S100A8,EED,CCAR2,TCP1,DYNC1I2,HNRNPL,TRIM35,CDK17,CCT7,EGLN3,WWP2,HR,PPP2R5A,PSMD3,XPO1,PPP3CA |
| 1.414e-05 | -11.17 | FAM120A (family with sequence similarity 120 member A) | protein interactions | 23196 | 336 | 130 | 19454 | 5460 |
VIRMA,FBLN5,CCNF,PSPC1,TRIM24,PRKRA,GSK3A,FGFBP1,RC3H2,CASC3,CDKN2AIP,UBE2H,IGF2BP1,ELAVL2,FBXW7,MRPL17,NPM3,SIRT7,PML,RPA3,HELLS,BAP1,RNF113A,HNRNPH2,TWNK,WWP1,ZNF326,DCTN4,MRPS34,RPA2,ZNF574,TFIP11,ATG16L1,RBFOX2,RBMS2,CFTR,CCL3,CGAS,MRPL50,CAND1,FZR1,MRPS23,MALSU1,RBM42,ALYREF,MRPS9,SYNCRIP,PRR3,SNRNP70,SSX2IP,RPS2,MOV10,GRSF1,HDAC6,HNRNPK,MSH6,MRPS18C,MAP1B,DHX9,MRPS18B,ZC3H11A,DISC1,MRPL51,ILF2,MRPL47,YTHDF2,STRBP,FBP1,APOBEC3D,MATR3,MAD2L2,GGPS1,CMTR1,MRPL13,DCAF4,MRPS25,BRCA1,NOA1,FBXW11,MCAT,CUL3,HNRNPC,MYC,STAU1,MRPL57,SSR3,YTHDF1,G3BP2,FTL,MRPS7,NGRN,RAB5A,AKAP1,LARP4B,WDR77,PABPC5,DUSP14,SPTAN1,PAIP1,RPS10,HNRNPL,FUBP3,SRSF1,ZCCHC9,HNRNPD,WWP2,CPEB1,HNRNPA1,NUP42,H1-6,G3BP1,RAD21,MRPS17,RBM3,LSM14A,HNRNPA2B1,PABPC1,RPL31,SRSF8,SRSF7,ZC3H7A,EFNB1,NGB,EZH2,SKA3,TOP3B,RAF1,PAIP2B,TNPO2,SOX2 |
| 1.416e-05 | -11.17 | SLC6A15 (solute carrier family 6 member 15) | protein interactions | 55117 | 143 | 64 | 19454 | 5460 |
PHB1,ACSL4,RAB35,RAC2,GJA1,HSD17B11,RHOH,ARL6IP5,SPPL3,ARF6,CAV1,LMAN1,DIRAS3,STX6,RAB5C,ADIPOR2,LAMP2,ATG9A,LAMP3,RHOG,STYK1,TMT1A,GARRE1,RAB1A,NTRK2,COX8A,RAB3B,KRAS,EPHA4,FLOT1,TP53,RAB4A,PTRH2,RPN1,STX12,RND3,VAMP3,LMBR1L,GPR89A,SEC61B,RHOJ,RAB14,RAB11A,RAB2A,DNAJC5,RHOB,LAMTOR1,NTRK3,RHOU,RAB5A,RAB9A,TLCD1,PXMP2,PIP4P1,STX7,BET1,HACD2,RND2,SEC62,CDC42,SSR1,GOLGA5,VAPB,MFAP1 |
| 1.416e-05 | -11.17 | MRPS18A (mitochondrial ribosomal protein S18A) | protein interactions | 55168 | 143 | 64 | 19454 | 5460 |
RPL10,MRPL23,RPL13A,RPL35,LRRC1,MRPL13,MRPL53,ZNF22,TACO1,RIT1,FBXW11,MRPL16,TUFM,MYC,AUH,PMPCA,MRPL20,MRPL17,MRPL40,MRPL57,MRPL41,HSPA8,GFM1,NGRN,MTRES1,MRPL10,MRPL12,RBMS2,RPL27A,MALSU1,MRPL24,FZR1,MRPL50,PRR3,FAHD1,GATD3,SSBP1,NOL12,RHOG,SKIC8,MRPL18,SNRNP70,TMEM70,HNRNPA1,MRPL9,MTRF1,RPL6,FASTKD5,RPL17,H1-6,KRAS,CTNNBL1,RPL23A,RPL3,SRSF7,MRPL52,MRPL33,MRPL51,MRPL49,APOBEC3D,AURKAIP1,METTL15,MRPL11,MRPL47 |
| 1.422e-05 | -11.16 | RPF2 (ribosome production factor 2 homolog) | protein interactions | 84154 | 223 | 92 | 19454 | 5460 |
RPL31,RPL28,KRAS,H1-6,HMGN4,OTUD6B,MAK16,SAP30,LGR4,DLG3,SART3,RPL18,CHMP4C,RPL8,SRSF1,DHX15,HNRNPL,LYAR,DDRGK1,IFI16,WWP2,NMRAL1,EP300,G3BP2,HSCB,UFL1,ZNF692,NOP53,STAU1,RND2,APOBEC3C,RPL37A,ESR2,RPL10,RPL35,RPF1,TUBB,ZNF668,MYC,DNAJB6,RIT1,NSA2,CDKL2,H1-1,FTSJ3,ATG3,RPL3,SNIP1,SEM1,RPL15,ILF2,RBM34,SRP14,KRR1,DKC1,ZBTB2,SURF6,GRSF1,CHCHD1,SNRNP70,MTDH,RNF113A,RPA3,PML,SIRT7,NLE1,AATF,DGCR8,NPM3,RPL4,FBXW7,RPS14,ATG16L1,RPLP0,MACROH2A2,RPA2,LMNA,GRM2,FGFBP1,PRKRA,PTEN,CCNF,EIF2AK2,SMURF1,SRPK2,RPL13A,DNAJC8,RPF2,RPL7A,UBE2H,MECP2,RC3H2 |
| 1.424e-05 | -11.16 | LGALS3 (galectin 3) | protein interactions | 3958 | 330 | 128 | 19454 | 5460 |
LPAR2,ATP2B4,RNF167,SLC6A8,TF,SLC29A1,TMSB10,FCF1,TBK1,TRIM6,SOD2,TSPAN3,DSTN,RPL12,ACTA2,TMPO,CDC5L,ALCAM,CSNK2A1,FCGR2A,HDAC6,C1GALT1C1,ITGA2,SQSTM1,SOD1,ABCC2,SLC5A6,CRYZ,GTF2I,LPAR1,CFTR,SPR,MYL12B,CAPN1,PDCD1LG2,GSTP1,ELMOD1,P2RY12,SDCBP,SLC12A2,STX17,GPR35,HBB,IDH2,SLC11A2,RPS20,CCNF,OPTN,ENO1,SH3BGRL,ACP2,TXN,PTPN11,RPL7A,ATP1A1,ABCG2,PPIG,UBE2H,TRIM23,SLC17A5,OSTM1,SLC25A5,SYPL1,FKBP2,IMPA2,KRAS,TRIM26,RRAGB,NCSTN,RAF1,ENPP4,ADCY3,TMEM182,VAMP2,CHMP4C,AQP3,IGBP1,MAP1LC3A,HEBP1,CD63,RAMP3,PPIA,RAB11B,HSP90AB1,SNRPD3,SLC38A9,CTNNB1,PRPF19,ATG9A,LAMP2,CRIP1,PTDSS1,CD58,AGR2,TRIM5,COX17,HSPA8,EMP3,TRIM22,PEBP1,TMEM160,FBXL4,NPTN,PRR13,SUFU,CSNK1A1,MYL6,KCTD12,ABCB1,PPARG,ACAA2,SNRPD1,SERINC1,SNRPD2,MCPH1,SLCO1B3,APLNR,ESR2,PTPRZ1,LGALS3,RPL35,AK3,SLC1A3,MYC,TMEM179B,SERPINH1,YWHAZ,BRCA1 |
| 1.429e-05 | -11.16 | ATXN2 (ataxin 2) | protein interactions | 6311 | 285 | 113 | 19454 | 5460 |
ABCE1,DHX9,SEM1,MDC1,KBTBD4,NAA35,CCT5,YTHDF2,APOBEC3D,ILF2,SRP72,SYNCRIP,FZR1,CAND1,RPS16,RBM42,CALR,MOV10,CSNK2A1,GAPDH,EDC3,SNRNP70,TDRD7,RPA3,LSM12,LCP1,RPL4,POLR1H,RBFOX2,MIR34B,TPT1,LPXN,RBMS2,WRAP53,RPA2,MIR7-1,PSPC1,CCNF,METAP2,PSMA6,SMAP2,RTRAF,RPS20,GMDS,SRC,VIRMA,EMILIN1,ST13,EIF3G,RC3H2,ELAVL2,PAIP2,IGF2BP1,CASC3,UBE2H,LSM14A,PABPC1,HNRNPA2B1,ZC3H7A,OAZ3,FHL3,RTCB,G3BP1,NUP42,PRPS1,B3GNT2,TOP3B,RAF1,ACTN4,ISG15,PLS3,FUBP3,PHB1,TSG101,FAM98A,HNRNPL,PEG10,EGLN3,NUP35,DHX15,WWP2,HNRNPA1,CPEB1,TRA2A,HNRNPD,DDX1,DRG1,MCRIP2,RCCD1,P4HA2,HSPA8,DDX5,AKAP1,FXR2,TRA2B,YTHDF1,STAU1,ASB3,G3BP2,PABPC5,IDH3B,CNPY3,LARP4B,NUFIP2,EIF4A2,ACTB,ESR2,PRRC2A,RPL10,RPL19,MYC,CUL3,HNRNPAB |
| 1.432e-05 | -11.15 | positive regulation of T cell proliferation | biological process | GO:0042102 | 103 | 51 | 18204 | 5365 |
IL6ST,LEP,CD40LG,PYCARD,AGER,PPP3CA,IL18,PNP,SASH3,HMGB1,CD1D,IL1B,DHPS,CD274,FOXP3,IL21,IL6,GPAM,SELENOK,RPS3,NCK1,TFRC,CD86,CCL5,CD209,IGF1,IL12B,XCL1,SLC7A1,IL1A,TGFBR2,CCR2,IL2,CCL19,EFNB1,AIF1,CD46,CD81,PDCD1LG2,MIR21,MIR30B,IL4,TRAF6,PRKCQ,CD28,CD80,IL23A,IL15,JAK2,EPO,IL2RA |
| 1.435e-05 | -11.15 | FAM135A (family with sequence similarity 135 member A) | protein interactions | 57579 | 81 | 41 | 19454 | 5460 |
RND3,RAB4A,FGFR1,RND2,CDC42,ATG16L1,BET1,UBA52,STX7,FLOT1,EPHA4,KRAS,RAB3B,RAB5A,NTRK2,RAB9A,ZYX,RHOU,GLUL,NTRK3,LAMTOR1,RHOG,RHOB,LAMP3,DNAJC5,LAMP2,RAB2A,ATG9A,RAB5C,RAB11A,DIRAS3,STX6,EGLN3,VIRMA,CAV1,RHOH,RHOJ,GJA1,HRAS,RAB35,TUBA1B |
| 1.440e-05 | -11.15 | MMS19 (MMS19 homolog, cytosolic iron-sulfur assembly component) | protein interactions | 64210 | 294 | 116 | 19454 | 5460 |
COPS5,HDAC6,ERCC3,EDEM1,ADD1,PWP2,HRAS,COQ8A,PTP4A3,ILVBL,KCTD3,PRNP,MAP2K3,APOO,COMTD1,SURF4,ABCE1,SLC25A11,KPNA2,CSE1L,AR,C9orf72,CIAO1,NRP1,STK11,ATP1A1,AP2A1,UBE2H,GEMIN8,EIF2S2,CTU1,CDIPT,CCNF,PPP1R10,RHOJ,PPAT,CDC42,ELP3,CNP,CFTR,WTAP,RSAD2,RPA2,METTL14,SSR1,SQSTM1,BAP1,PRIM2,RPA3,POLD2,PML,MBD3,AATF,EIF5B,MRPL40,NUCKS1,XPO1,DDRGK1,CIAO3,DICER1,SLC25A28,MAGED2,XPO5,EGLN3,ELK1,NUP35,CDK17,EIF2S1,RHOH,SUMO2,NCSTN,MAK16,SOX2,ERLIN2,GTF2E2,B3GNT2,SPC24,RAF1,TOP3B,MOB3C,RHOBTB1,RPN1,PRPSAP1,ABCF1,LTO1,MSL2,KRAS,DCP2,RFC5,MLF2,MYC,CUL3,ILK,RIT1,THOC6,GTF2F1,LMBR1L,S1PR4,ARF1,EIF3K,APLNR,SNRPB2,ESR2,IDH3B,RND2,FOXS1,USP39,APOBEC3C,LARP4B,EP300,AKAP1,DUSP9,POLA2,NPTN,NDUFS2,PHB2 |
| 1.444e-05 | -11.15 | HBP1 (HMG-box transcription factor 1) | protein interactions | 26959 | 121 | 56 | 19454 | 5460 |
SAP30L,RPL18,HBP1,RBM34,SAP30,SMAD1,SUPT5H,SMN1,RPL28,SRSF12,SRSF4,PAK1IP1,RBBP7,TRIM26,EWSR1,MKLN1,PPAN,MAEA,TOP2B,NKRF,MAP1B,ARMC8,RB1CC1,TUBG1,BAZ1B,DKC1,BRMS1L,RPL35A,NOB1,NOP58,HP1BP3,RB1,MRTO4,RPL32,SYNCRIP,SIN3A,LARP4B,CD2AP,BRIX1,RANBP10,RPL4,EP300,GID8,PNO1,GID4,RRP7A,UBE2H,FBXW11,FTSJ3,BRMS1,RIOK2,CREBBP,MYC,MACROH2A1,ING2,RAN |
| 1.447e-05 | -11.14 | BCL6 (BCL6 transcription repressor) | protein interactions | 604 | 226 | 93 | 19454 | 5460 |
AIP,EPHB6,KARS1,IRF4,CRBN,SSX2IP,BRD3,TCOF1,NKRF,SFXN1,LPAR2,ABCE1,CTNNBL1,FARSA,OLA1,ZNHIT1,MTA3,ATP5PB,TP53,YTHDF2,PPIF,CDK8,SRP72,RAD23B,ENO1,GANAB,ZBTB17,PRKCE,JUNB,TRAF1,USP14,AR,PPTC7,DVL2,PML,GFM1,PRDX6,HDAC3,LITAF,MBD3,BCL6,WDR83,SIPA1L1,CCL3,SPMIP6,TFIP11,WTAP,PCDH9,SIN3A,PSMB4,TRAF3IP3,CCT7,MDFI,CNOT2,PFDN5,UTP6,CTNNB1,AK2,KDM2A,DROSHA,FBXO11,PSMA1,PELI1,ZBTB16,RAF1,CFAP97D1,TRAF2,JUN,RPN1,ITGB5,KLHL12,PRMT5,PSMD4,MED17,SIAH1,APEX1,ACO2,CREBBP,CUL3,HBEGF,CFAP161,MCM4,MCM3,HSP90AA1,SP1,PRKD3,HDAC5,EP300,ARRDC3,PHB2,ETF1,MED23,CTBP1 |
| 1.447e-05 | -11.14 | TUBB6 (tubulin beta 6 class V) | protein interactions | 84617 | 226 | 93 | 19454 | 5460 |
HSPA8,UCHL3,G3BP2,WDR77,SRXN1,MYC,CUL3,BTF3,TOMM40,CCT2,FAS,BRCA1,NTRK3,KLK5,ICAM1,COP1,DNAJB6,ILK,HTRA2,OSTM1,EPHA4,G3BP1,AHCYL1,RAF1,B3GNT2,DNAJC25,TUBA1A,ISG15,EZH2,TUBB4B,CHMP4C,MOB3C,PHB1,FBXO32,PCSK9,SUMO2,TCP1,ELK1,EGLN3,CCT7,UBXN6,SAV1,AGR2,INPPL1,RPA3,BAP1,PML,RNF113A,FBXW7,PIK3R2,HSPA5,CLU,CCND1,GABRA1,CFTR,TCP11L1,FGFR1,HEXIM1,CCNF,TUBA1B,KCTD9,NDN,VIRMA,FBXO7,TUFM,TXNIP,DNAJC19,UBE2H,IGF1R,RBCK1,MEPCE,RIGI,MAP2K3,CTDSP2,ZMYM4,TFCP2,CAPZA2,FURIN,RCHY1,EEF1AKMT3,TES,FZR1,CDK9,MOV10,DPP4,MICB,USP2,DNAJB2,HDAC6,PPM1D,CD81,SNRNP70,SHC1 |
| 1.451e-05 | -11.14 | ISY1 (ISY1 splicing factor homolog) | protein interactions | 57461 | 132 | 60 | 19454 | 5460 |
SNIP1,ZC3H11A,KRAS,CTNNBL1,CDC40,TSSC4,NUP42,POLE4,SNRPG,RIGI,SSRP1,CD2BP2,ESS2,DDX39A,CDK8,ILF2,SNRPE,BUD31,SNRPD3,SNRPA1,TOP1,CDC5L,CWC15,PRPF19,MOV10,ZCCHC10,TRA2A,SNRNP70,KIAA1143,BRD3,SNRPA,NKAPD1,RCCD1,CWF19L1,RBM22,STAU1,SAP18,PABPC5,ATG16L1,WDR83,SF3A1,SNRPN,RALYL,TFIP11,PSMA6,GCFC2,UBE2I,SNRNP40,LMO2,HNRNPC,SNRPB,CPSF2,MECP2,FBXW11,LMNB1,EXOC8,ELAVL2,MAPRE1,UBE2H,RIT1 |
| 1.451e-05 | -11.14 | MYEF2 (myelin expression factor 2) | protein interactions | 50804 | 132 | 60 | 19454 | 5460 |
SIRT7,RPA3,RNF113A,MIRLET7I,HDAC5,OIP5,ATG16L1,MIR34B,RPA2,MIR21,SCLT1,RPLP0,MIRLET7B,RPL37A,PRMT5,PRKRA,MATR3,ESR2,TRAF1,MIRLET7D,MYC,AR,GMPS,TRIM23,RC3H2,MIR363,MIR9-2,SFXN1,MIR200A,ERP29,FLOT1,ACTN4,MIR15A,SOX2,MIR20A,EZH2,MIR17,STX12,RAB35,MIR141,MIR25,EED,NKAP,LYAR,MIR9-1,MIRLET7G,PRNP,NUP35,ERLIN1,MIR429,STOML2,DDRGK1,HNRNPA1,MIR29C,MIR31,AGR2,SNRNP70,MIR34A,MIR221,HNRNPD |
| 1.451e-05 | -11.14 | ADD3 (adducin 3) | protein interactions | 120 | 132 | 60 | 19454 | 5460 |
LAMP2,RAB5C,LAMP3,XPO1,RHOG,HSPB1,HRAS,RAB35,GJA1,ADD1,RAC2,ARF6,RHOH,DYNC1I2,LMAN1,DIRAS3,STX6,CAV1,RAF1,TP53,HDAC11,CAPZA2,RND3,THNSL1,GPSM3,KRAS,G3BP1,ADD2,FLOT1,RIGI,RAB2A,CUL3,OPRM1,FAM78A,RAB11A,DNAJC5,LAMTOR1,RHOB,CYP1A1,MAPRE1,CCNF,GSK3A,UBE2I,DAPK1,STAT5A,ACTB,RHOJ,CLDN4,RND2,CDC42,RPA2,FEM1A,BORCS8,ARL15,PRKCA,RPA3,RHOU,PML,RAB9A,STX7 |
| 1.454e-05 | -11.14 | GPR152 (G protein-coupled receptor 152) | protein interactions | 390212 | 197 | 83 | 19454 | 5460 |
COMT,MFSD5,SLC66A2,FA2H,STX5,LHFPL2,ANKRD46,FUNDC2,CNIH1,TSPO2,TMEM97,AIG1,TMEM237,CLEC1A,TMEM208,SLC38A7,CD81,FAM20B,ORMDL3,SLC41A1,TMEM42,ZDHHC15,STX8,TMEM50B,UNC50,ERG28,TSPAN7,TMEM60,ADIPOQ,GPR37L1,SFT2D2,LEPROTL1,SACM1L,PGAP2,NEU1,INSIG2,UBIAD1,YIPF4,MFSD6,TFRC,SFTPC,AQP3,TMEM14B,CYB5B,CDIPT,CYB5R3,CYBC1,MGST3,THBD,MMD,EFNA5,TM4SF19,GJB2,VAMP5,CSGALNACT2,SLC35B4,HMOX2,CYB561,CGRRF1,PLN,SLC38A1,TMEM100,REEP6,FAXDC2,TEX264,JAGN1,ORMDL1,TMEM254,RABAC1,TMEM243,SLC7A1,SLC35F6,SEC22B,TIMMDC1,AGTRAP,BET1,GOSR2,EDDM3B,CCDC167,VAMP1,CTXN3,SMCO4,FDFT1 |
| 1.468e-05 | -11.13 | ribosomal large subunit biogenesis | biological process | GO:0042273 | 68 | 37 | 18204 | 5365 |
RPL7,MAK16,ZNHIT3,NSA2,RPL10,NOP53,RSL24D1,RPL7L1,RPL35A,RPL10L,NOP16,MALSU1,ZNHIT6,TRAF7,RPL26,RBM34,BRIX1,MRTO4,WDR12,RPF2,NLE1,PAK1IP1,FTSJ3,ZNF622,PPAN,RPL26L1,RPL23A,RPL6,RPL7A,RPF1,SURF6,CINP,RPL35,MRM2,TMA16,LTO1,RPLP0 |
| 1.470e-05 | -11.13 | MRPL50 (mitochondrial ribosomal protein L50) | protein interactions | 54534 | 229 | 94 | 19454 | 5460 |
E2F4,FLOT1,IMMP2L,GTF3C3,HSPD1,SRSF7,COX8A,HINT2,MRPL18,RHOG,TST,MRPS26,MRPS35,MTRF1,TRA2A,MRPL9,HNRNPA1,SRSF10,GATD3,MRPS18A,SLC25A3,RPL27A,MRPL12,MRPL57,HSCB,TMEM177,TRA2B,SAP18,EXD2,NGRN,MRPL34,CUL3,PMPCA,MYC,AUH,MTG2,MRPL16,RPL35,REEP3,MRPL23,RPL19,CCDC90B,MTG1,TACO1,MRPL13,MRPL49,MRPL51,MRPL33,GFM2,ILF2,MRPL47,MRPL11,METTL15,DUSP1,AURKAIP1,RPL17,FASTKD5,MRPL22,SLC25A10,MRPL52,TMEM70,CHCHD1,SNRNP70,SMAD4,GRSF1,MRPL50,MRPL24,MALSU1,ALYREF,SSBP1,MRPS9,SYNCRIP,PRR3,MTRES1,RBMS2,KLF12,MRPL10,MRPL41,MRPL40,MRPL17,MRPL20,NHP2,ZC3H15,GFM1,RC3H2,TEX19,UBE2H,DNAJC19,MED22,TUFM,RPL26,VIRMA,SUCLG2,MRPL53 |
| 1.470e-05 | -11.13 | SPPL2B (signal peptide peptidase like 2B) | protein interactions | 56928 | 229 | 94 | 19454 | 5460 |
EXTL2,SPPL3,TMED9,SLC39A10,HACD3,FITM2,OSBPL8,UPK1A,FAM187B,ATP1B1,TMBIM6,CCR6,RIGI,PSEN1,ATP1A2,EMC2,STX18,TMED1,TSPAN3,TMEM165,SURF4,YIPF4,MTCH2,TMEM126A,ACP2,UQCRQ,VKORC1L1,MGST3,SLC11A2,ATP1A1,ENDOD1,PIP4P1,LPAR1,SLC7A1,MAVS,NDUFC2,CYC1,PIGW,CDR2,CHRNB2,GHITM,GOLGA5,GALNT1,HACD2,ADIPOR1,FUT8,EDDM3B,COX14,RMND1,UQCRH,HNRNPL,MCOLN1,ADGRG1,MFSD5,HAS3,PSME2,NDUFB8,PEX3,FXYD6,FAM20B,HS2ST1,ROCK2,PGAP4,SLC35G2,TMT1A,GPAA1,CRELD1,KDELR1,NRN1,MOXD1,YIPF3,TOP3B,NDUFAF4,ABHD12,SYNE4,GPR89A,RCE1,SERINC1,SLC30A7,VMP1,ATP1A3,SLC30A5,TMED4,CERS6,TMED3,RER1,NDUFS2,TLCD1,SLC35F2,CAV2,SIGMAR1,YIPF5,SLC19A2,TMEM231 |
| 1.478e-05 | -11.12 | MAGT1 (magnesium transporter 1) | protein interactions | 84061 | 177 | 76 | 19454 | 5460 |
VDAC1,TGFBR2,FKBP8,NSDHL,LDLRAD4,SKA3,RPN1,CA14,PLD3,TP53,B3GNT2,CCDC47,CFAP68,RAF1,NCSTN,TUBA1A,CLEC2B,DNAJC25,FZR1,DNAJC1,CD151,COX4I1,PTPN1,CD274,RAC2,EED,RHOG,SMAD4,SLC25A46,RPL6,MOV10,DDRGK1,NKIRAS1,PPIB,FBXW7,SSR3,HSCB,HSPA5,TSPAN5,DAD1,TMEM106B,RPA3,DNAJC3,SQSTM1,DERL1,EP300,PRKCB,HSPA8,GRM2,SSR1,FOXS1,LMNA,RPA2,CHRNB2,TMEM231,CDK7,ST7,CDC42,RND2,OTULINL,FBXO22,ESR2,TECR,LMBR1L,VDAC2,SEC61B,SEC61A1,DNAJC10,LMNB1,CALU,TYROBP,NTRK3,OST4,COX10,TOMM40,TIA1 |
| 1.485e-05 | -11.12 | MRPL43 (mitochondrial ribosomal protein L43) | protein interactions | 84545 | 160 | 70 | 19454 | 5460 |
TUFM,MTG2,MYC,AUH,PMPCA,RIT1,DNAJC19,TAFAZZIN,RC3H2,MRPL13,MRPL53,TACO1,MTG1,CCDC90B,PRRC2A,RPL10,RPL19,MRPL23,PSMD4,LAMTOR3,MRPL10,MRPL12,RBMS2,MTRES1,GFM1,NGRN,EXD2,MRPL20,CRYZ,FXR2,HSCB,MRPL40,COPS5,HNRNPA1,MRPL9,MTRF1,GRSF1,MRPS26,RHOG,MRPL18,SMAD4,SNRNP70,CHCHD1,TMEM70,GATD3,SSBP1,ALYREF,COX4I1,MALSU1,MRPS23,CAND1,MRPL50,AURKAIP1,METTL15,RAF1,MRPL11,NDUFA2,E2F4,MRPL47,GFM2,MRPL51,HINT2,MRPS11,MRPL52,HSPD1,SNIP1,FASTKD5,UTP25,KRAS,H1-6 |
| 1.497e-05 | -11.11 | Activated TLR4 signalling | REACTOME pathways | R-HSA-166054 | 115 | 58 | 10285 | 3229 |
TBK1,NFKBIA,MAP2K3,TLR1,SKP1,CD36,PPP2R1A,PELI1,UBB,PELI3,UBA52,TLR4,PTPN11,MAP2K1,MEF2C,TLR6,S100B,DUSP6,TAB1,FOS,ELK1,CREB1,TANK,FBXW11,LY96,JUN,AGER,IRAK4,NFKB1,MYD88,CD14,DUSP3,TRAF6,HMGB1,UBE2D1,BIRC2,TICAM2,TLR2,IKBKB,SARM1,RPS27A,UBE2D3,UBE2N,TIRAP,MAPK10,IRF3,MAPKAPK3,TLR3,MAP2K6,ATF1,TAB2,NFKBIB,DHX9,MEF2A,IRF7,UBE2V1,TICAM1,PPP2CB |
| 1.499e-05 | -11.11 | ZC3H13 (zinc finger CCCH-type containing 13) | protein interactions | 23091 | 146 | 65 | 19454 | 5460 |
PEA15,SMARCA5,OST4,PPP1CC,RNF40,ANAPC15,IFI6,SNRNP40,MED17,TCEAL7,VIRMA,ESR2,SRPK2,SH3BGRL,POLR2B,EIF4A3,EZH1,METTL14,MED23,WTAP,EHHADH,ATG16L1,PABPC5,MED30,PSENEN,HSPA5,SAP18,SIRT7,NLE1,BAP1,CLK1,HSPA8,SNRNP70,MED29,MED21,DDX23,MED27,ANKRD50,MAGOH,UQCR11,USP15,MED4,ID1,WDR11,CSNK2A1,YWHAG,HNRNPA1,YWHAH,THOC1,CDK9,ALYREF,EED,CBX3,SCHIP1,TMEM14B,MED9,DHX38,WBP11,ASF1A,KRAS,PTGES3,SSRP1,RUSF1,RPL31,RING1 |
| 1.508e-05 | -11.10 | GSTM4 (glutathione S-transferase mu 4) | protein interactions | 2948 | 16 | 13 | 19454 | 5460 |
ZBTB16,LRIF1,GSTM4,IGSF21,AGR2,GSTM2,HEXIM1,MED31,GSTM3,TLE1,TP53,GSTM5,BAG3 |
| 1.508e-05 | -11.10 | Hedgehog ligand biogenesis | REACTOME pathways | R-HSA-5358346 | 67 | 38 | 10285 | 3229 |
PSMC1,PSMC4,ERLEC1,PSMD12,PSMA3,PSMB5,PSMB1,OS9,PSMB7,PSMD3,PSMA6,PSMB3,PSMA2,PSMB6,PSMD1,PSMB2,PSMB10,PSMA5,PSMC5,PSMB11,PSMA4,PSMD7,SEM1,PSMB9,PSMB4,PSME1,PSMD6,PSMD10,PSME2,UBB,PSMD4,SYVN1,RPS27A,UBA52,PSMA1,DERL2,PSMC3,PSMD14 |
| 1.515e-05 | -11.10 | epithelial cell proliferation | biological process | GO:0050673 | 175 | 78 | 18204 | 5365 |
IFT57,KIT,SOX9,THAP1,CDKN1B,PROK1,CLEC12B,TRIM24,AR,PSEN1,DLG1,LIPA,CCND1,IGFBP3,SFN,B4GALT1,BMPR1A,FGF1,VSTM4,CDKN1A,SDR16C5,CAV2,OR51E2,BCL2L1,LIMS2,CAV1,BAD,MEF2C,RB1,IGFBP4,CD34,BMPR2,NCSTN,MAP2K1,VEGFA,SAV1,FABP7,EPHA2,ERRFI1,BTBD10,FGF7,HNF1B,STK11,PROX1,STK3,MTA3,NKX3-1,SEMA5A,PHB2,EAF2,NOG,STAT6,CDH13,STK4,WDR77,RAF1,MMP14,OVOL1,RBPJ,NOTCH2,IFT52,HMX2,TNF,CCL5,BGLAP,PRKX,IRF6,LGR4,WNT2,CCN3,FGF10,CTNNB1,IFT172,BAX,BAK1,SERPINB1,IL6,FLCN |
| 1.527e-05 | -11.09 | PNP (purine nucleoside phosphorylase) | protein interactions | 4860 | 76 | 39 | 19454 | 5460 |
GMPS,GLO1,HNRNPA1,IFI16,MOV10,MYC,UBE2H,TRAPPC4,NOS1AP,AGR2,MTAP,GNPDA1,GATD3,ZHX1,ENO1,CCDC90B,ENO2,CCNF,OPTN,LRIF1,PNP,ECHDC1,CFTR,SOX2,TP53,NCALD,SHOC2,PPME1,CHMP4C,RAB4A,RPA2,DERL1,ABCE1,SIRT7,RAB1A,RPA3,BAP1,RIGI,TMEM177 |
| 1.529e-05 | -11.09 | regulation of transporter activity | biological process | GO:0032409 | 253 | 106 | 18204 | 5365 |
MIR873,MIR34B,MIR133B,CACNB2,WWP2,NLGN1,IFNG,MIR1-1,AHCYL1,ATP1B3,HPCA,SCN1B,DAPK1,MMP9,MIR34A,MIR186,YWHAH,STAC3,NETO1,OXSR1,PHB2,HOMER1,FGF12,DLG4,OPRM1,CLIC2,KCNAB1,EPO,CAV1,COX17,EDNRA,MIR129-1,NDUFA4,FKBP1B,CAV3,PRRT1,GPR35,MIR33B,FXYD6,TLR9,MIR208A,NOS1AP,GSTO1,SELENON,STIM1,PPARG,MIR212,MIR153-1,CACNG3,ADIPOQ,ACTB,MIR192,MIR24-1,CHP1,CACNB3,ABCB1,SCN3B,TCAF2,VMP1,CRHBP,MIR9-1,CLTRN,MIR30D,RANGRF,MIR495,GSTM2,CAB39,MIR208B,TESC,HECW1,DRD3,ADRB2,FKBP1A,CTTNBP2NL,SYNGR3,KCNS1,CCL2,MIR200C,VAMP2,PCSK9,SLMAP,JPH4,TMSB4X,SPHK2,ACTN4,PRKCE,CACNB4,CHRM3,KCNIP2,FGF13,SRI,CRHR1,MIR448,SUMO1,PLN,MIR17,SCN2B,CFTR,NDFIP1,NLGN2,CCR2,ATP1B1,CAPN1,PPIF,DLG1,ATP1A2 |
| 1.529e-05 | -11.09 | DPYSL2 (dihydropyrimidinase like 2) | protein interactions | 1808 | 203 | 85 | 19454 | 5460 |
STAU1,GPM6A,MARS1,VPS28,EIF4E,SIRT7,RPA3,BAP1,ARFIP1,HSPA8,RNF7,RPA2,PAK2,TPD52L1,RARS1,UBL3,EEF1E1,CAPN1,WDR83,NEK7,EIF3J,CDC42,TUBB,TENT5C,PRDX2,RANBP6,VIRMA,DYRK1A,ROCK1,RAN,CCNF,UBE2I,AP2M1,BICD2,CGRRF1,YWHAZ,UBE2H,RRP7A,AP2A1,MARCHF3,CRMP1,CUL3,CUL2,MAT2A,MYC,RACGAP1,PPP1CC,GORASP2,RUNX1,TOLLIP,G3BP1,AP1M1,CCT8,RAB1A,ERO1A,SCPEP1,SPSB3,NGB,DISC1,EZH2,PLS3,OTULIN,E2F4,CCT5,LYPLA1,TRAF2,TUBA1A,PLEKHF2,HNRNPL,HSP90AB1,G6PD,NTMT1,TRMT61A,ARMC1,TNIK,TSG101,FKBP4,MAP4,HAX1,CBL,CDC23,WWP2,KARS1,GAPDH,XPO1 |
| 1.530e-05 | -11.09 | E5b (E5b protein) | protein interactions | 1489367 | 180 | 77 | 19454 | 5460 |
QPCTL,TOR4A,TMEM30A,SLC2A1,ESYT1,GJA1,STT3A,SRPRA,COMT,ERLIN1,TMPO,DNAJB9,RPS27L,FAF2,ERLIN2,PREB,SELENOK,MTCH2,RAP1A,PLD3,GPD2,STIM1,SURF4,TMEM165,RPL3,BSCL2,TMX3,SLC25A11,NDUFA4,ATP2B4,RPS13,FKBP8,RDH11,RAB18,PLPP6,SACM1L,SRPRB,PSMD1,HMOX2,UFD1,CHPF,RETSAT,CNTNAP1,ATP1A1,SNX14,ENDOD1,RPL37A,SLC30A7,FZD6,GGT7,SEC61B,CDIPT,CHCHD3,ABHD12,VKORC1L1,SEC63,COPE,LRRC8A,RPL13A,TRAM1,CNP,PGRMC1,NOTCH2,SEC22B,FAM8A1,PIP4P2,STOM,MMP14,GREM1,RTN4,GRAMD2B,APMAP,ATP2C1,GLIPR1,ATP5MK,LRP10,STAU1 |
| 1.532e-05 | -11.09 | ACKR2 (atypical chemokine receptor 2) | protein interactions | 1238 | 89 | 44 | 19454 | 5460 |
SURF4,KDELR1,TMEM126A,YIPF3,PGAP4,CCL2,PRELP,SACM1L,TMEM87A,ATP2B4,EFNB1,FAM241B,CCL11,CCL5,ARL6IP5,DERL2,PTPN1,SIGMAR1,GHITM,GOLGA5,CCL21,CCL19,CAV2,RABL3,SLC19A2,SEC62,YIPF5,CCL3,SLC7A1,CERS2,TMEM167B,CMTM6,RER1,CCL8,ATP5IF1,CCL27,CCL25,ENDOD1,CREB3,CCL28,REEP4,VKORC1L1,EFNA5,SCAMP2 |
| 1.532e-05 | -11.09 | ASGR2 (asialoglycoprotein receptor 2) | protein interactions | 433 | 89 | 44 | 19454 | 5460 |
EIF1AX,GOLGA5,TFRC,HACD2,SEC22A,UBIAD1,PLP2,BET1,JMJD8,TRAM1L1,HSPA5,FKRP,ADIPOQ,ERLEC1,CERS2,TMEM60,EGFL7,DERL1,SYVN1,ORMDL1,CLEC7A,TIMP3,STX8,RPL23,PLN,SLC35A1,HMOX2,FATE1,SLC38A9,PMP22,VAMP5,EDEM1,OS9,AIG1,TSPO2,VTI1B,SENP5,FA2H,ADGRL3,SERINC1,SCAMP2,PTPN1,ACSL4,RPRM |
| 1.532e-05 | -11.09 | GPX4 (glutathione peroxidase 4) | protein interactions | 2879 | 89 | 44 | 19454 | 5460 |
ENO2,GLRX2,ENO1,RAB35,VDAC2,AKR1B1,LHFPL4,IL18,TAX1BP1,PRDX2,TAGLN2,PTPN11,CUL3,PPIB,ATP5F1A,CYB561,UBE2H,RIT1,SOD1,SQSTM1,HINT1,HSD17B10,PRDX6,ELOF1,VDAC1,ETFA,HSPE1,UCHL3,G3BP1,SNRNP48,KRAS,HNRNPA0,HSCB,RIGI,IMPA2,FKBP2,COIL,ETFB,RPE,PPIF,GSTO2,FKBP1A,UBE2M,SOD2 |
| 1.539e-05 | -11.08 | Validated targets of C-MYC transcriptional activation | Pathway Interaction DB | myc_activpathway | 81 | 47 | 2226 | 782 |
MMP9,GAPDH,CCNB1,SMAD3,EIF2S1,MYC,IREB2,MAX,MTDH,TERT,GPAM,TAF9,RIOX2,TFRC,ODC1,SLC2A1,SERPINI1,EP300,BAX,SUPT3H,HMGA1,SMAD4,LDHA,CDK4,TAF10,PDCD10,HUWE1,ENO1,SUPT7L,PMAIP1,RUVBL2,NME2,EIF4E,MYCT1,SHMT1,BIRC5,NDUFAF2,HSP90AA1,RUVBL1,ACTL6A,NME1,PEG10,HSPD1,PRDX3,CREBBP,NBN,TP53 |
| 1.544e-05 | -11.08 | molecular adaptor activity | molecular function | GO:0060090 | 1138 | 404 | 18094 | 5411 |
HNRNPA2B1,MAP2K1,FHL3,ATG16L1,SHC1,STX7,KCTD17,SAP18,RNF14,NEFL,NCSTN,TSG101,BEND6,SMARCB1,MED22,BICD2,TGFB1I1,CD274,TRIM37,ALKBH5,GAB1,RIOX2,MED31,IFNAR1,PEX26,TRIM8,ATP1B3,VAMP7,NCK1,RBBP8,SUPT3H,NLRP6,G3BP1,NUCKS1,PRNP,JCHAIN,ACTN4,NUP62,COPS5,LPXN,SQSTM1,CBX5,RNF20,PIH1D1,COL1A2,IDE,LMO3,SERTAD2,IRAK1BP1,EP300,ST13,LMO4,KGD4,DVL2,EMILIN1,TIRAP,SNAP29,SMARCD3,NKAP,NAPG,TAX1BP1,FBXO42,DUSP19,TAF5L,OPTN,SEC22A,SDCBP,FBXW11,HIRA,KLHL25,KLF4,TCAP,STX10,PTPN11,DDX4,PRMT2,AP1S2,FLRT2,LGALS3,TRIM52,NR0B1,LDB1,SDR16C5,EID2B,MTA2,FOXP3,PSMD4,HR,CREBBP,CCND1,SETD5,G3BP2,STAP1,CUL2,ZMYND11,SUFU,TRIP4,MECP2,VAMP1,DGCR8,IRF2BP1,DET1,TAB2,ELK1,DTL,KLHL15,CDC42SE2,EID2,STX1A,FEM1B,LAMTOR2,DNAJB2,TRIM62,TRIM11,NUP153,PQBP1,CRYM,FKBP4,TRIM15,GNB4,PML,NLRP3,TOPBP1,STX16,THRAP3,BCL9,MED13L,EWSR1,TOLLIP,FBXO3,NFKBIB,AR,AP1M1,RB1,CNOT7,CDC20,TOB2,NIBAN2,MIDEAS,RAB3A,PSMD10,GFI1,NME2,FBXO7,AIP,EZH2,SURF6,SKP1,SOCS2,CSTPP1,PCMTD1,HMGA1,TCOF1,DISC1,SPSB1,LDB2,DDIT3,SAP30L,ISCU,NAB2,PCLAF,RLIM,SIN3A,BRD3,ACTL6A,PCBD1,VGLL2,DYRK1A,NHERF1,IGF2BP1,RRAGA,STX18,TICAM1,PEX3,TRAF3IP3,ATP1B1,ARL2BP,BTG1,FBXO9,VAMP3,TRIM22,PRPF31,HMGB1,DLGAP4,CTNNB1,UBE2L3,ALYREF,VTI1B,PSMG3,ERG28,TYROBP,VAMP8,NCOA5,BECN1,SERINC1,EEF1A1,SETD4,SEPTIN6,SIAH2,RB1CC1,LDLR,NFKB1,APH1A,WDR77,STUB1,TRIM27,SEC22B,NAB1,TRIM32,GOSR1,SUPT7L,BTG2,SP1,ENO1,PFDN5,CGAS,LAMTOR3,SGTA,YKT6,TOMM70,TRIM6,HNRNPC,BUD31,BCL10,BFAR,DLG1,ZBED1,MED21,KLHL3,HCFC2,THAP7,FAF2,CAV2,DNAJC2,ACSS2,MED27,YTHDF1,TANK,CITED1,TAF11,PHF12,TGFBR2,DHX16,IFI27,HRAS,SOD3,NBN,SS18,GNB3,TADA3,MED9,KLHL22,USE1,VPS18,MED11,RUVBL2,RUVBL1,CNOT2,GNB1,MDC1,STX5,H2AZ2,FBXW7,DHRS7B,TRIM5,TICAM2,EDF1,LMO2,FEM1C,RETREG1,PIAS1,MED17,ZNF451,CTBP1,CRADD,MED4,TAF9,SH3BGRL,TRIM24,APEX1,HDAC3,STX12,HOMER1,GAS2,STX17,HYAL2,AP1G2,KDM2A,ING2,SLA2,RXRG,STX11,AP2S1,SEPTIN7,NAPA,CHCHD3,RACGAP1,RETREG3,JADE1,STX8,DYRK1B,CAV3,SMARCE1,GOSR2,MAVS,MED30,IRF4,PPP1R3C,TAPBP,SPATA2,TLE1,MED23,MSL2,BET1L,MTDH,PSMG2,CUL3,FZR1,RBFOX2,AP2A1,EZH1,DDX1,ELOC,ENY2,RAP2C,ROPN1B,YTHDF2,APPBP2,CNOT6,PHB1,PIR,JUP,PIK3R1,FLRT3,CIDEB,PAXX,BET1,UBE3A,PRKCB,TADA1,TAB1,NFE2L2,SAV1,SUB1,SARM1,HSPA8,FRS3,NUPR1,AGER,PRDX4,RETREG2,NLRP1,WBP2,SRSF2,PRMT5,CCAR1,BIRC2,CSNK2B,TRAF2,STX6,SAP30,COPS2,HPF1,C1D,RERE,USP16,NOS1AP,YAF2,SNAP25,EID1,CD3G,SNAP23,USP15,AP2M1,KDM1A,MED29,FEM1A,DMAP1,MYD88,MTA3,SSBP3,FBXL19,BRCA1,CDKN1B,TRIM21,GMNN,CRKL,FIS1,KRAS,VAMP2,HAX1,NDC80,SETD3,ARF6,DHX9,HSBP1,CBFB,ACTL6B,PHF13,CAV1,LAMTOR1,HCLS1,MED10,GRB10 |
| 1.553e-05 | -11.07 | H1-3 (H1.3 linker histone, cluster member) | protein interactions | 3007 | 241 | 98 | 19454 | 5460 |
TP53,CDK4,NUPR1,RNF181,RBM34,NECAP1,RIGI,MEPCE,RPS13,HDAC6,CD81,GRSF1,BRD3,RPS2,CHCHD1,KRR1,CTDSPL2,SURF6,AKAP17A,DKC1,CDK9,RPS16,CDK7,HEXIM1,RPL26L1,PRKCA,UBE2M,RPA2,CDK1,RNF113A,SIRT7,RPA3,HELLS,UTP23,AATF,NUCKS1,RPS15,USP14,ZSCAN25,RPS17,UBE2H,UBASH3B,RPS3,CTSB,RAF1,CHMP4C,EZH2,GLE1,MYO1B,TRIM21,EWSR1,RPL31,RAD21,IRAK4,RPS27A,RPL28,H1-6,DDRGK1,NGDN,RPL6,HMGA1,IFI16,DCAF4L2,POU5F1,HNRNPD,MRPS26,NCK1,AGR2,WDR12,RPS10,H1-5,CSNK1A1,RAB5A,EP300,SF3B1,NMRAL1,GPC1,NOP53,STAU1,ZNF668,PSMD1,CUL3,SFN,GRB10,NOP16,H1-1,ICAM1,RPS5,FTSJ3,LMNB1,ZCRB1,PSMD14,H1-10,SF3B4,ZNF22,ESR2,USP38,RPF1 |
| 1.556e-05 | -11.07 | Downstream signaling events of B Cell Receptor (BCR) | REACTOME pathways | R-HSA-1168372 | 197 | 90 | 10285 | 3229 |
PIP4K2C,HRAS,GAB1,PPP2CB,KIT,AKT3,AKT1,PSMA6,PIK3CA,PSMD1,PSMB2,FGF16,BCL10,PSMC1,IER3,CD86,PSMA1,TP53,PSMC3,PSMD4,RPS27A,PSMB4,IKBKB,RASGRP3,SEM1,FGF23,PSMA5,PTEN,MET,NFKB1,PSMB3,PPP2R5E,PIP5K1A,ICOS,PIK3R2,PPP2R5A,FGF1,MDM2,KRAS,TNRC6C,UBA52,FGF22,SRC,PSMD10,NFKBIA,FGF10,PIK3AP1,MOV10,AKT2,PIK3R3,PRKCB,CDKN1A,NFKBIB,PSMD12,FGF7,GSK3A,BAD,PSMD6,HBEGF,FGF3,PSME2,PSMB9,FGFR1,PSMC5,PSMB11,PSMB10,PSMA4,CD28,PSMB6,PSMA2,FBXW11,PIK3R1,PSMB1,CREB1,PSMD3,PSMB7,CDKN1B,PSMC4,PSMB5,PSMA3,PTPN11,PSMD14,UBB,PPP2R1A,SKP1,PSME1,AGO1,PSMD7,FGF17,CD80 |
| 1.556e-05 | -11.07 | mitochondrial ribosome | cellular component | GO:0005761 | 89 | 45 | 19108 | 5553 |
MRPL33,MRPS7,MPV17L2,MRPS17,MRPL47,MRPL52,MRPL41,MRPS21,MRPS16,MRPL11,MRPL20,MRPL22,MRPS18A,MRPL40,MRPS18B,MRPL18,MRPL57,MRPS18C,MRPL50,MRPL51,MRPS9,MRPL24,MRPL16,MRPS26,MRPL10,MRPS11,MRPS35,MRPL13,CHCHD1,MRPS25,MRPS34,AURKAIP1,MRPL53,MRPS28,MRPL9,MTG2,MRPL34,MRPL49,MRPL17,MRPS33,MRPL36,MRPS23,MRPL23,MRPL12,MTG1 |
| 1.556e-05 | -11.07 | organellar ribosome | cellular component | GO:0000313 | 89 | 45 | 19108 | 5553 |
MRPL23,MRPL12,MRPL50,MRPS18C,MRPL36,MRPS23,MRPS33,MRPL57,MRPL17,MTG1,MRPL24,MRPS9,MRPL51,AURKAIP1,MRPL53,MRPS34,MRPS18A,MRPL22,MRPS25,MRPL18,MRPL49,MRPL34,MRPS18B,MRPL40,MTG2,MRPS28,MRPL9,MRPL20,MRPL11,MRPL13,MRPS16,MRPS21,MRPL41,CHCHD1,MRPL47,MRPS17,MRPS11,MPV17L2,MRPL10,MRPS7,MRPL33,MRPS26,MRPL16,MRPS35,MRPL52 |
| 1.556e-05 | -11.07 | regulation of nucleocytoplasmic transport | biological process | GO:0046822 | 111 | 54 | 18204 | 5365 |
HYAL2,TXN,IER3,EFCAB7,NCBP2,MDM2,RAB23,EP300,IFNG,MX2,SIRT7,SMAD3,CHP1,XPO1,THOC2,PTPN11,HSP90AA1,LEP,PKIA,NRDE2,PPP1R12A,IL1B,DMAP1,ANGPT1,CDK5,CDK1,CTDSPL2,DHX9,UHMK1,CD36,PPP1CC,SUMO1,IFI27,JAK2,HCLS1,MAVS,CHCHD4,SFN,AKAP8L,NUP153,CAMK1,PSEN1,UFM1,PIK3R2,HDAC3,RIOK2,PIK3R1,PKIG,RAN,RBM22,SUFU,ANP32B,JUP,BAG3 |
| 1.561e-05 | -11.07 | RAB35 (RAB35, member RAS oncogene family) | protein interactions | 11021 | 559 | 202 | 19454 | 5460 |
SLC12A2,GOLGA5,PICALM,JUP,LMNA,TIMM23,AGAP1,SEC22B,ARHGAP1,PIP5K1A,UBA52,ATG16L1,RABL3,CNP,CD200,PIK3R2,SLC7A1,NF2,YKT6,TMEM209,CDC42EP4,RPA3,ITGA2,MAVS,GPX4,FLCN,MAPRE1,NRP1,EPHA2,HMOX2,DEPDC1B,YES1,RHOJ,RAB14,F11R,SEC63,CEP97,FERMT2,TECR,SH3BP4,CTNNA1,HYCC1,GAB1,VAMP3,KRIT1,CASK,CCDC47,RPL15,SLC29A1,LBR,ADD2,ARF4,CTNND1,GARRE1,DLG1,NSDHL,RAB1A,SNAP23,SEPTIN7,ESYT1,TIAM1,SLC2A1,OSBPL8,TMEM199,RELL1,DAG1,HM13,HDAC6,ALCAM,ARF6,CAV1,EHBP1,SRPRA,WDCP,PTPN1,CDCA3,VAPB,NOTCH2,PGRMC1,EHD1,PPP1CB,IDH3B,SNX24,STX7,EXD2,PMAIP1,CLDN1,RHOB,LMNB1,FAS,CBR3,SCFD1,PKP4,PIK3R3,NIBAN2,VEZT,TOMM40,MAP3K21,TUBB,FAM91A1,ARF1,GDI2,RPN1,EZH2,VAMP2,STIM1,STX12,MACO1,TULP3,FAF2,SEMA4C,AHCYL1,AKT2,SCYL2,PLCB1,C2CD2L,PIK3R1,SNX2,SPTAN1,OCRL,CNTROB,MYEF2,WDR6,GJA1,RPA2,CSNK1G3,LEMD3,HEXIM1,PDCD1LG2,SPTBN1,CDC42,TEX264,DERL1,ARFIP1,ATP1A1,RPL7A,C9orf72,RAB2A,GORASP2,CNNM4,ARHGAP21,TRIM54,ROCK1,NECTIN2,UQCRC2,MOB4,TFRC,EXOC3,RAP1A,PREB,SNAP29,UBL4A,UBIAD1,AKAP12,FKBP8,SLC6A8,ATP2B4,PALM2AKAP2,ABCE1,SLC16A1,RPL3,NOS1AP,TUBG1,FCHO2,CD99L2,SLC38A2,LMAN1,CAMLG,ITGA6,CD274,RAC2,GNPAT,RAP1B,ADD1,SLC39A10,UBAC2,CAV2,USP6NL,ABCC5,AKAP1,LAMTOR1,SLC38A1,SLC1A3,DTD2,ACAP2,ATP6AP2,ESR2,EFHD2,FAM83B,CA14,MOB3C,ADCY3,STBD1,SLC20A2,TMEM87A,EFNB1,DDRGK1,CTNNB1,PPFIBP1,VAMP7,CD63,STX5 |
| 1.563e-05 | -11.07 | - | gene3d domains | 1.20.5.110 | 48 | 28 | 14470 | 4137 |
STX17,STX1A,TRAF1,STX7,STX11,SNAP23,STX12,STX6,BET1,BCAP29,VTI1B,YKT6,VAMP2,STX10,MFN1,SNAP29,VAMP1,VAMP7,STXBP6,VAMP8,SEC22B,STX8,SNAP25,STX16,VAMP3,VAMP5,BET1L,STX18 |
| 1.563e-05 | -11.07 | XPNPEP1 (X-prolyl aminopeptidase 1) | protein interactions | 7511 | 105 | 50 | 19454 | 5460 |
IRGQ,RAF1,HEXA,GDE1,GUCD1,DISC1,RBPJ,MTMR2,RAD23B,RINT1,PCNA,PDE12,CSE1L,VTA1,DCTPP1,RNF20,MOV10,KARS1,API5,ELOC,AGR2,ATP6V1D,ATP6V1A,RPL35A,SUMO2,PRNP,RHOH,EHD1,GTF3C4,NUDT3,LMNA,PLAA,RPA2,RPA3,HSPA8,RAB30,UBE2D3,DUSP26,PYGB,POLA2,MARS1,HMGCS1,RNF40,BAG3,GORASP2,STXBP6,H2AZ2,CCNF,GNPDA1,MYG1 |
| 1.571e-05 | -11.06 | PPP1R8 (protein phosphatase 1 regulatory subunit 8) | protein interactions | 5511 | 97 | 47 | 19454 | 5460 |
SNRNP27,PPP1CB,GTF2E2,STXBP1,SF3A1,WDR77,NUPR1,VPS4B,EZH2,LSM2,ERG28,HSPA8,APPBP2,SF3B1,RTCB,DDX39B,SNRPA,FBXO25,SSRP1,CTNNBL1,NF2,KRAS,CSNK2A1,PPP1CC,SNRPB,HMGA1,CREBBP,PRPF19,DDX1,CRMP1,DNAJB6,RIT1,NME2,BICD2,CYP1A1,SHC1,ATG3,PREP,EED,FBXO32,PPP5C,WIF1,CDC5L,RPL35A,RBBP4,TOP1,SNRNP40 |
| 1.582e-05 | -11.05 | SLC33A1 (solute carrier family 33 member 1) | protein interactions | 9197 | 183 | 78 | 19454 | 5460 |
RAC2,HSD17B11,PTPN1,HSP90AB1,OPRL1,ILVBL,RBM42,TMPO,TRIR,DNAJC1,ARF6,LAMP3,RAB5C,FAM20C,LAMP2,HAX1,CBL,ESYT1,TRAPPC2L,SLC2A1,RHOG,SLC39A7,BSCL2,TMT1A,RAB1A,TRAPPC1,CYP2C9,FKBP8,RAB3B,ARL5B,KRAS,DNAJC25,MACO1,PLD3,AQP3,RAB4A,STIM1,RPN1,SEC61B,ARF1,NUDT18,LMBR1L,APLNR,TAGLN2,RAB14,ATP5F1A,GPBAR1,RAB11A,GPR17,RAB2A,MAT2A,MCAT,RIT1,PDF,CHRAC1,LMNB1,EP300,RAB9A,DERL1,SYVN1,ATP5F1E,VIPR1,STX7,EEF1G,NF2,SLC7A1,CFTR,ST7,OTULINL,CDC42,SEC62,ACACA,UBE2M,HSP90B1,SSR1,GPR35,LMNA,ATP5PO |
| 1.582e-05 | -11.05 | RO60 (Ro60, Y RNA binding protein) | protein interactions | 6738 | 183 | 78 | 19454 | 5460 |
UGP2,HSPA5,SMC4,HSPA8,RPA3,PPM1G,PRPF4,RPLP0,PSMB7,RPA2,CDC42,UQCRQ,VIRMA,MATR3,PSMD6,SNRNP40,ACTB,ADRM1,TUBB,RBBP4,PPAT,PSMC5,PRMT5,SNRPD2,MACROH2A1,RPS9,LMBR1L,RPS3,TUBA1B,ELAVL2,IGF2BP1,BRCA1,PSMD1,CREBBP,MYC,CSK,CARS1,SUB1,CUL3,HNRNPAB,PAGR1,MEPCE,UBE2A,AHCYL1,PSMA1,HNRNPF,RUVBL1,TRIM21,RUVBL2,PDIA6,DHX9,PPP1R12A,METTL18,FAF1,RBM3,PABPC1,HNRNPA2B1,ILF2,MTA2,GFPT1,ACTN4,EGLN3,FZR1,HNRNPL,SEC23A,COPS2,SYNCRIP,PHB1,HNRNPD,MAP4,USP15,IKBKB,SNRNP70,RPL24,COPS5,HNRNPA1,GAPDH,PSMD3 |
| 1.583e-05 | -11.05 | SLC25A51 (solute carrier family 25 member 51) | protein interactions | 92014 | 149 | 66 | 19454 | 5460 |
USP30,FKBP8,NDUFB5,RUSF1,BSCL2,CLPB,GPD2,CTLA4,NDUFS3,NDUFS6,NEFL,NDUFA12,FAM162A,DDX39A,NDUFS8,TOMM70,SLC25A12,CAV1,MRPS9,AIFM1,COX4I1,PHB1,OCIAD2,CDCA3,AK2,SLC2A1,FKBP4,SMIM12,HAX1,UQCC6,MRPS35,COX5A,STOML2,NDUFS2,PHB2,HIGD2A,TXNL1,TMEM126B,AKAP1,HADHA,MAVS,MRPS34,COX6C,SAMM50,STOM,UBAC2,NDUFA5,PTAR1,FAM234A,MTX2,TIMMDC1,HCST,TIMM13,TIMM29,CDC20,CHCHD3,PARL,NDUFAF4,SCN2B,DLST,PTPMT1,CHCHD6,BOLA1,NDUFB10,FMC1,COX6B1 |
| 1.583e-05 | -11.05 | MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like) | protein interactions | 25902 | 149 | 66 | 19454 | 5460 |
MAPK10,MTARC2,APOO,AURKAIP1,CMPK1,TOP3B,HGS,PDHA1,NDUFS6,EZH2,COX8A,HAPSTR1,HINT2,HSPD1,IMMP2L,XPNPEP1,TGFBR2,COPS5,WWP2,DPP4,GRSF1,CNN3,RHOG,FAHD1,GATD3,FBXO32,COX4I1,AIFM1,CDK9,MALSU1,EGLN3,TRAPPC6B,PAPOLB,RPS16,TPT1,PAFAH1B1,MTRES1,PIH1D1,METTL14,ISOC1,QRSL1,RPA2,AKAP1,HSPA8,EXD2,AMACR,SIRT7,RPA3,NT5C3A,TOMM20,ADRB2,HSCB,UFL1,CASP4,PAPOLA,CUL3,MYC,UBE2H,COP1,TXNIP,SMU1,OPTN,CCNF,VIRMA,FBXO22,TAGLN2 |
| 1.583e-05 | -11.05 | ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) | protein interactions | 471 | 149 | 66 | 19454 | 5460 |
SIRT7,SNRPA,BAP1,RPA3,RTN4,STK26,HSPA8,OXCT1,NSFL1C,SHMT1,SPR,PAFAH1B1,ISOC1,STOM,CTBP1,RPA2,SHOC2,KCNAB1,UBE2M,LMBR1L,CCNF,GNPDA1,MSN,CMBL,GSK3A,PRKCE,TENT5C,GMDS,TXN,NDN,LDHA,MYC,ARMT1,RIT1,UBE2H,NAE1,EMC2,HAPSTR1,JAK1,KRAS,SAR1B,RIGI,HNRNPDL,TP53,KBTBD4,RAF1,PGM1,EEF2,ISG15,ACTR2,ACOT13,EZH2,CAPN2,TYMS,SUMO2,PRNP,CAV1,IFI16,GLO1,CTNNB1,YWHAG,ATG7,HDAC6,AGR2,NME2,HSPB1 |
| 1.583e-05 | -11.05 | MRPL48 (mitochondrial ribosomal protein L48) | protein interactions | 51642 | 149 | 66 | 19454 | 5460 |
RPL18,MRPL51,PDHA1,AURKAIP1,KIF2A,METTL15,MRPL47,MRPL11,MEPCE,FASTKD5,RPL17,IMMP2L,H1-6,HINT2,RPL23A,COX8A,SRSF7,HSPD1,MRPL52,LSM14A,MRPS26,MRPL18,RHOG,CHCHD1,SNRNP70,MRPL9,HNRNPA1,GRSF1,MTRF1,MALSU1,SPPL3,MRPL50,GATD3,FAHD1,SSBP1,SDHB,ZNF574,MTRES1,MRPL10,RBMS2,MRPL12,ATG16L1,LSM8,EMC1,HSCB,MRPL41,FBXW7,MRPL40,EXOSC4,GFM1,NGRN,EXD2,IGF2BP1,TUFM,MTG2,AUH,PMPCA,RPL10,RPL19,MRPL23,RPL35,RPL13A,MRPL13,TACO1,MRPL53,CCDC90B |
| 1.589e-05 | -11.05 | DDX50 (DExD-box helicase 50) | protein interactions | 79009 | 247 | 100 | 19454 | 5460 |
RPL3,SNIP1,RPL17,MEPCE,MAP1LC3B,AURKAIP1,TP53,MRPL11,RBM34,RAC2,ARL4D,KRR1,PTPN1,CD274,SURF6,ZBTB2,CAND1,RPS16,SLC25A46,GRSF1,RPL10A,NOL12,SNRNP70,H2AC4,RNF113A,MTDH,PRKCB,PML,GID8,RPA3,GID4,AATF,RPL4,NPM3,DGCR8,FGF13,ST7,GABRA1,AGO1,CDC42,KLF4,RPLP0,HEXIM1,ZNF574,RPA2,PTEN,FGFBP1,PRKRA,ZNF330,SRPK2,RPL13A,RNASEH1,DEPDC1B,RPL7A,UBE2H,MAPRE1,RC3H2,RPS24,SRSF7,MKLN1,MAEA,RPL31,RPL28,CHCHD2,G3BP1,KRAS,SOX2,CHMP4C,GATD3,EED,SRSF1,RPL8,RPS10,DDRGK1,CPEB1,WWP2,IFI16,LHX2,ARMC8,DDX23,RHOG,EP300,RANBP10,STAU1,UFL1,FXR2,RPS9,SEC61B,RPL10,RPL19,APEX1,RPL35,SNRNP40,BTF3,ZNF668,CUL3,AUH,MYC,H1-1,LMNB1 |
| 1.597e-05 | -11.04 | IRAK2 (interleukin 1 receptor associated kinase 2) | protein interactions | 3656 | 56 | 31 | 19454 | 5460 |
COQ8A,STT3A,SESTD1,HRAS,SARM1,SMURF1,SUB1,TNFAIP3,BAG3,IQSEC1,TRAF6,LACRT,RNF152,PELI3,HSP90AA1,SMAD2,MYD88,MME,TLR4,TOLLIP,YTHDF1,PELI1,IRAK4,TICAM2,PSEN1,FASTKD5,TIRAP,MAP2K1,TLR3,SH3GLB1,SH3GLB2 |
| 1.597e-05 | -11.04 | MPV17 (mitochondrial inner membrane protein MPV17) | protein interactions | 4358 | 56 | 31 | 19454 | 5460 |
MRPL13,VDAC2,NDUFB4,UQCRH,NDUFS8,APEX1,HNRNPL,MRPL23,RALA,LAMTOR3,NDUFB7,MOV10,NDUFB6,STK11,SCFD1,ATP6V1D,MRPS16,NDUFB5,NDUFA4,MRPL22,RPS15,MRPL17,HSCB,MRPL40,CYB5R1,MRPL11,NDUFA12,MRPL51,SLC25A24,FAM3C,NDUFS6 |
| 1.599e-05 | -11.04 | NIT2 (nitrilase family member 2) | protein interactions | 56954 | 71 | 37 | 19454 | 5460 |
ENO1,CREB1,ACAT1,PRNP,TENT5C,LDHA,HNRNPL,SUCLG2,LDHB,ACO2,RNASET2,NPTX1,GMPS,LYPLAL1,S100A11,PEDS1,GSTO1,AK2,SORD,NQO1,PEBP1,PRDX6,PSMG4,NPTN,TMEM177,CRYZ,CMPK1,CFTR,MRPL12,PGM1,CCS,ISG15,ACAA2,PPT1,NUDT19,PIR,SOD2 |
| 1.599e-05 | -11.04 | PSMG2 (proteasome assembly chaperone 2) | protein interactions | 56984 | 71 | 37 | 19454 | 5460 |
POMP,CCDC22,PSMD7,RIT1,PSMG3,PSMB2,PSMA4,FBXO7,PSMB6,PSME2,PSMA6,PSMB5,PSMB4,PSMC5,PSMB1,PSMB7,RPA2,SOST,PSMC3,FAM89B,RAF1,SLC35F6,WDR83,PSMB3,PSMB9,PSMA5,PSMA1,KRAS,PSMA2,SEM1,PAFAH1B2,FARSA,CA10,RPA3,PSME1,PSMG4,PSMA3 |
| 1.599e-05 | -11.04 | Dnajc17 (DnaJ heat shock protein family (Hsp40) member C17) | protein interactions | 69408 | 71 | 37 | 19454 | 5460 |
CDC40,HNRNPF,RBM22,RUVBL1,CWF19L1,RUVBL2,RPL3,BAG2,RPS24,TFIP11,RPLP0,RPL18,SNRPA1,SNRNP40,SNRPD3,TUBB,RPL35,RPL13A,RPL7,CDC5L,DHX15,RPL10,RPS3,RPL12,GCFC2,TUBA1B,SNRPD1,SNRPD2,RPLP2,RPS9,RPLP1,YWHAZ,RPL10A,PRPF19,HNRNPC,RPL7A,RPL26 |
| 1.599e-05 | -11.04 | BTBD2 (BTB domain containing 2) | protein interactions | 55643 | 71 | 37 | 19454 | 5460 |
ERG28,TRIM5,RIGI,SAR1B,IGSF21,COPS4,PTN,TTC4,KPNA2,OTUD6B,EEF1A1,SMAD1,RBM12,TP53,UBE2M,NGB,COPS2,HRAS,PNMA1,CINP,CCDC90B,CEP97,SRC,COPS7B,SVIP,TOP1,COPS5,RUNX1,NTAQ1,GAPDH,DDX50,COPS7A,CUL3,TLE1,COP1,CRMP1,SMAD2 |
| 1.600e-05 | -11.04 | Glutathione metabolism | KEGG pathways | hsa00480 | 54 | 34 | 7161 | 2463 |
IDH2,GPX2,GSTM5,GPX5,GSTP1,LAP3,RRM1,GSTA4,GPX1,HPGDS,GSTM4,GGCT,GSTO1,G6PD,GSTA2,GCLC,ODC1,GPX6,GSTO2,GPX4,MGST2,GSTM3,IDH1,SRM,TXNDC12,GPX3,MGST3,GSTT1,GPX7,GSTT2B,GSTA1,GSTM2,GGT7,GSTK1 |
| 1.600e-05 | -11.04 | Glutathione metabolism | KEGG pathways | ko00480 | 54 | 34 | 7161 | 2463 |
GPX4,GSTO2,GSTM3,MGST2,GCLC,GSTA2,GPX6,ODC1,GGT7,GSTM2,GSTA1,GSTT2B,GSTK1,IDH1,GPX3,SRM,TXNDC12,GSTT1,MGST3,GPX7,GSTP1,GPX5,LAP3,RRM1,GPX2,IDH2,GSTM5,HPGDS,GGCT,GSTO1,G6PD,GSTM4,GSTA4,GPX1 |
| 1.601e-05 | -11.04 | glutathione transferase activity | molecular function | GO:0004364 | 29 | 20 | 18094 | 5411 |
GSTO1,GSTA1,GSTK1,GSTM5,GSTM4,GSTA2,GSTT2B,HPGDS,MGST2,ALOX5AP,CLIC2,LANCL1,GSTM3,GSTM2,GSTO2,GSTA4,MGST3,GSTP1,GSTT1,PTGES |
| 1.619e-05 | -11.03 | SET (SET nuclear proto-oncogene) | protein interactions | 6418 | 253 | 102 | 19454 | 5460 |
EP300,HSPA8,FOS,MRPS7,CDKN1A,PIH1D1,KCTD12,GTF2F2,VPS72,APEX1,ACTB,RPL35,RPL7L1,MATR3,THAP7,IRF1,NOP16,CUL3,H1-1,ICAM1,FTSJ3,FYTTD1,COX8A,UBE3A,RPS24,CDK5,PIK3CG,PPAN,RPL31,PAX6,H1-6,PPP2R1A,SOX2,SUPT5H,MARCKSL1,ANP32A,CDK5R1,H2BC1,NME1,CHMP4C,USP46,PPP2CB,SWAP70,SUMO2,CTNNB1,XPO1,PDIA3,MGMT,AGR2,DDX23,BANF1,BAP1,RPA3,SOD1,UTP23,UGP2,FTH1,UBE2M,HEXIM1,RPL26L1,METTL14,RPA2,SDCBP,MACROH2A1,TRIM24,PTEN,ZNF330,ENO1,CCNF,VIRMA,JUNB,FBXO7,SUB1,CCNB1,HSPA14,GZMK,UBE2H,TRIM23,RPL23A,FAF1,MEPCE,TRIM63,HUWE1,NEDD8,H3C1,H2AX,CHRM3,TP53,NUPR1,GNPDA2,CBX3,KRR1,RCHY1,H2AZ1,MDM2,FZR1,GAPDH,CD81,FAM20C,SPATS2L,TOPBP1,BRD3 |
| 1.619e-05 | -11.03 | C8orf82 (chromosome 8 open reading frame 82) | protein interactions | 414919 | 166 | 72 | 19454 | 5460 |
MRPS35,MOV10,GRSF1,NDUFV2,MRPS26,FUBP3,MRPS9,GATD3,CCAR2,MRPL50,HNRNPL,MRPS23,MRPL24,CCT7,ATP5PD,NDUFS8,ETFB,NDUFA2,ATP5PB,BCS1L,NDUFS3,NDUFS6,CASK,NDUFA12,HNRNPA2B1,HSPD1,HINT2,MRPS18B,KGD4,ETFA,HNRNPK,MRPS33,POLDIP3,HNRNPDL,MRPS18C,MRPS17,MRPL22,PYCR1,PYCR2,NDUFAF2,MRPS25,CCT2,SPOP,MRPS16,IGF2BP1,DLST,TACO1,VAMP3,CPSF1,PSPC1,MRPL53,ACAT1,MRPS28,ATP5F1B,MATR3,MRPL23,APEX1,NDUFAF4,NDUFAF3,MRPL12,MRPS34,QRSL1,ATP5PO,NDUFA5,LEMD3,MTRES1,EXD2,GFM1,MRPL41,NDUFS2,NME4,MRPS7 |
| 1.619e-05 | -11.03 | YME1L1 (YME1 like 1 ATPase) | protein interactions | 10730 | 166 | 72 | 19454 | 5460 |
AK2,ASIC2,TMEM70,HAX1,HSPB1,MAPK4,DDRGK1,SPPL3,ADCK1,EIF2B5,EGLN3,TOMM70,LRRC61,COX14,SLC25A12,COQ8A,SSBP1,AIFM1,COX4I1,SMARCB1,GEMIN7,PLD3,ATP5PB,E2F4,TUBA1A,APOO,DNAJC25,KRAS,USP30,PSEN1,IMMP2L,FKBP8,SFXN1,CLPB,OPA3,COX8A,TYROBP,FIS1,HTRA2,DNAJC19,MYC,NDUFB6,CUL3,ATP5F1A,RANBP6,CHCHD3,SEC63,PARL,ESR2,MAD2L2,LMBR1L,CCNF,PTEN,RPA2,PDP2,GP9,SAMM50,ELOVL1,ATG16L1,COQ8B,TIMMDC1,MTX2,TIMM13,TIMM29,DUSP22,CFTR,EMC1,PHB2,FBXW7,SLC25A51,RPA3,AKAP1 |
| 1.646e-05 | -11.01 | MARK2 (microtubule affinity regulating kinase 2) | protein interactions | 2011 | 259 | 104 | 19454 | 5460 |
RAF1,SOX2,PPP2R1A,STIM1,RND3,GPSM3,KRAS,NUP42,FLOT1,LAMP2,IFI16,ATG9A,RAB5C,YWHAH,HNRNPA1,YWHAG,STK4,DDRGK1,RHOG,YWHAB,CAMSAP2,WDR6,RAB35,GJA1,RHOH,DIRAS3,HSP90AB1,STK3,RND2,PRDX3,CDKN1A,JAKMIP1,RAB5A,UFL1,PHB2,STX7,RNF41,CREBBP,MYC,PMPCA,SFN,RAB11A,CAV3,LAMTOR1,RHOB,YWHAZ,PFDN2,HSP90AA1,AP2M1,RMDN3,FBXO22,MANSC1,ESR2,APEX1,APOO,CAMK1,ACTR2,CAPZA2,CASK,GARRE1,MRPL22,CAPZA1,LAMP3,SMAD4,STYK1,HRAS,NAP1L5,RAC2,ARF6,SPPL3,LMAN1,STX6,TMCC2,CAV1,CDC5L,ATG16L1,CDC42,AGO1,FGF13,RPA2,PARD6A,TRIM36,DVL2,RHOU,MIS12,RAB9A,RAB2A,AKT1,FBXO7,DNAJC5,SPOP,RC3H2,STK11,UBE2H,GAB1,TMEM74,GSK3A,PPP2R5E,DAPK1,MAP3K3,PRKCE,RHOJ,SMURF1,VIRMA |
| 1.657e-05 | -11.01 | NDUFAF3 (NADH:ubiquinone oxidoreductase complex assembly factor 3) | protein interactions | 25915 | 116 | 54 | 19454 | 5460 |
HSCB,NDUFS2,GFM1,TMEM126B,NGRN,DUSP9,SNRPA,EXD2,CYC1,MTRES1,RNF146,CDC42,DHRS4,NDUFAF3,TIMMDC1,AGTRAP,NDUFAF4,PARL,ESR2,MRPS21,LMBR1L,CCNF,TACO1,CCDC90B,UHMK1,DNAJC19,TUFM,AUH,MYC,MTG2,NDUFB10,PMPCA,FASTKD5,IMMP2L,RBCK1,DNAJC30,COA4,HINT2,HSPD1,NDUFB5,NDUFA4,NDUFS3,APOO,MRPL11,EGLN3,NDUFS8,RMND1,FZR1,GATD3,COX4I1,MRPS26,RHOG,CHCHD1,TMEM70 |
| 1.670e-05 | -11.00 | MTAP (methylthioadenosine phosphorylase) | protein interactions | 4507 | 84 | 42 | 19454 | 5460 |
CYRIB,EFHD2,SNX12,ATP6V1A,PNP,TAGLN2,SNX3,SUMO3,TENT5C,PRNP,GLRX,CAV1,APEX1,PDIA3,CFL1,MTPN,CUTA,AR,GMPS,AGR2,CHRAC1,UBE2H,BAP1,RAB1A,RPA3,APPBP2,TAGLN3,HINT1,UBE3A,UFM1,CSE1L,NT5C3A,ARF4,LYPLA2,RBM12,MYLIP,PPIL3,SOX2,RPA2,GNPDA2,SCLT1,PIH1D1 |
| 1.670e-05 | -11.00 | COX7A2L (cytochrome c oxidase subunit 7A2 like) | protein interactions | 9167 | 84 | 42 | 19454 | 5460 |
NDUFS8,MYL12A,UQCRH,UQCRQ,RMND1,MGST3,ATP5F1B,ACTB,CORO1C,VDAC2,UQCRC2,COX4I1,CYB5R3,PHB1,TOMM40,COX6B1,COX5A,HSCB,NDUFS2,PDHB,VDAC1,PHB2,GNG5,COX8A,HADHA,RPA3,NDUFA4,ATP5MK,SLC25A3,CYC1,GPR34,RPA2,COX6C,NDUFS3,COX7B2,HSP90B1,PDHA1,COX4I2,UQCRC1,TOMM22,MTCH2,TIMMDC1 |
| 1.670e-05 | -11.00 | PTAR1 (protein prenyltransferase alpha subunit repeat containing 1) | protein interactions | 375743 | 84 | 42 | 19454 | 5460 |
TMEM165,GOLGA5,FBXO8,PGGT1B,VPS54,TRAPPC13,TAPT1,RABL3,YIPF5,SGMS2,SLC25A51,USP8,PHB2,GOSR1,GTF2I,YKT6,UBE2D3,RAB18,SKP1,SECISBP2L,SLC35A2,SYPL1,RAB1A,CMTR2,SNAP23,SPTSSA,RABGGTB,UNC50,NXT2,EXOC2,SSX2IP,EXOSC1,VPS39,SPPL3,CCT7,CNIH1,SLMAP,CCDC90B,CTDSPL2,VAMP3,NAA30,SGMS1 |
| 1.681e-05 | -10.99 | MSX2 (msh homeobox 2) | protein interactions | 4488 | 189 | 80 | 19454 | 5460 |
PREB,CCDC47,TOP3B,MSX2,DDX39A,PLS3,DTD1,TENT5D,PABPC1,RPL31,DHX9,RPS24,HNRNPK,TOLLIP,HSPE1,MAPK1IP1L,NEDD8,PRPS1,TLE1,GSTM3,PRDX1,HMGA1,HNRNPA1,RPL10A,MT1X,RPL12,DYNC1I2,RPL7,FAM98A,DNAJC1,HSP90AB1,EPHB6,PRR13,SPTBN1,H1-5,SF3A1,EIF3J,HSP90B1,PPARG,FKBP1A,TMEM263,XRCC5,RPL27,PYM1,PGK1,RNF34,SRI,YTHDF1,NUCKS1,MSX1,HMGB1,EEF1G,PTN,CSRP1,LDHB,HNRNPC,RPL7A,MGAT5B,PSMD1,MTPN,H1-10,YWHAZ,CKB,CHORDC1,MDH1,POU1F1,ATP1A1,RPS5,TMA7,SMAP2,RPS3,FAU,GTF2F2,GTF2F1,TUBB,RPL35,TSN,ZBTB17,ATP5F1B,LDHA |
| 1.682e-05 | -10.99 | SLC35C2 (solute carrier family 35 member C2) | protein interactions | 51006 | 127 | 58 | 19454 | 5460 |
ORMDL1,EMP3,SMCO4,VAPB,SYNDIG1,SYS1,FDFT1,FAM3C,SEC22B,GOSR2,PDCD1LG2,BET1,CCDC167,PLP2,SEC22A,THBD,TVP23B,TECR,EFNA5,PLP1,VEGFA,CYBC1,CYB561,PLN,CREB3,TMEM60,TF,ADIPOQ,DNAJC30,LEPROTL1,SACM1L,RIGI,RUSF1,STX8,TMEM50B,TMEM147,YIF1A,TMEM31,SLC35F1,TMEM14B,CYB5B,INSIG2,SELENOK,YIPF4,NRM,VTI1B,TMEM97,CNIH1,TSPO2,TMEM14A,SSMEM1,FA2H,FXYD6,BTN2A2,SLC38A7,EMC6,TMEM107,ORMDL3 |
| 1.690e-05 | -10.99 | regulation of cold-induced thermogenesis | biological process | GO:0120161 | 151 | 69 | 18204 | 5365 |
RHEB,IL4,BSCL2,HDAC3,GHRL,GJA1,ADRB3,DHRS7B,ACOT13,FABP4,HADH,FOXC2,CCR2,IRF4,ARRDC3,WNT10B,FABP5,KDM1A,ALPL,SLC25A44,NR1H2,ELOVL6,JAK2,CAV1,IL15,MAP2K6,ACHE,RB1,DIO2,G0S2,CD36,VEGFA,TFE3,PLAC8,IL18,SYK,ID1,TSHR,TLR4,ADRB2,ADIPOR1,GRB10,DDIT3,LEP,STK11,NOVA1,ATF4,CXCR4,STAT6,IP6K1,ADRB1,HCRT,RBPJ,PLCL1,ADIPOQ,UCP2,ELOVL3,IL13,OXTR,LGR4,ADIPOR2,GADD45G,LEPR,PRKAB1,CPT2,IGF1R,ABHD6,DBH,FLCN |
| 1.697e-05 | -10.98 | BUB3 (BUB3 mitotic checkpoint protein) | protein interactions | 9184 | 218 | 90 | 19454 | 5460 |
PIH1D1,LZTFL1,STAU1,UFL1,TMEM106B,EP300,BRCA1,PSMD14,CCT2,RIT1,CUL3,CUL2,ACO2,MYC,BTF3,KANSL3,ESR2,APEX1,MAD2L1,PARP2,RPL37A,CHMP4C,EZH2,MOB3C,RAF1,JUN,RBBP7,KRAS,RERE,UBE2A,CCT8,AGR2,CDC23,WWP2,ZNF207,DDRGK1,XPO1,TCP1,CCT7,EGLN3,PHB1,KCTD20,DNM2,METTL14,RPA2,HECTD1,CFTR,CXXC1,PML,NLE1,HCFC2,RPA3,DVL2,BTBD10,SQSTM1,ANAPC16,UBE2H,SMAD2,DTL,ZBTB38,ANAPC4,NDN,COPE,BUB3,CDC20,UBB,PTEN,EXOC3,RNF8,RNF181,NUPR1,TP53,CCT5,CENPM,HUWE1,BHLHE40,FAF1,MAP1B,HSD17B10,SNRNP70,HDAC6,COPS5,TOP1,PRNP,NKAP,CPNE1,FZR1,CDC5L,ACTA2,SMAD3 |
| 1.699e-05 | -10.98 | organelle fusion | biological process | GO:0048284 | 127 | 60 | 18204 | 5365 |
CHCHD3,YIPF4,BET1,STX17,SYT4,FIS1,CHMP4C,VAMP3,YIPF5,MCL1,CHMP5,MFN1,VPS16,STX12,STX6,SNAP23,PARL,VIPAS39,VTI1B,CHMP2B,VPS18,SNAPIN,CIDEB,PLA2G5,CAV2,STX7,BCL2A1,STXBP1,VAMP2,THG1L,CHMP2A,STX16,SNAP25,VPS39,STXBP6,STX11,SNAP29,STX8,STX1A,CDK1,CHMP1B,VAMP8,VPS33A,TOM1,CHMP1A,GOSR1,USP30,MIEF1,VAMP7,CLTRN,VPS4A,SEC22B,BAK1,BAX,GOSR2,STX10,VAMP1,VCPIP1,STX5,STOML2 |
| 1.717e-05 | -10.97 | RBM34 (RNA binding motif protein 34) | protein interactions | 23029 | 286 | 113 | 19454 | 5460 |
AURKAIP1,TAF1D,RPL15,LLPH,DNAJC2,HBP1,SRP72,RPL3,RPL23A,H3C1,PAK1IP1,TOLLIP,IMP4,RPS13,GRSF1,DPP4,CSNK2A1,CHCHD1,SNRNP70,NOL12,RPS2,RPL10A,COQ8A,RPL32,KRR1,ALYREF,RPL35A,FZR1,PRNP,CGAS,DKC1,CDK9,KLF9,SURF6,RPA2,RPL26L1,RPLP0,ACACA,MACROH2A2,RPA3,SIRT7,NLE1,MTDH,RNF113A,DERL1,DGCR8,NPM3,RPL4,STK38,UTP23,BRIX1,RPF2,RPL7A,PPP1CC,ZSCAN25,RC3H2,UBE2H,ZNF330,PRKRA,FGFBP1,RBMX2,RPL13A,SMURF1,SRPK2,RAF1,H1-3,MAK16,SOX2,HDAC11,RPL18,RPL31,RPS24,H1-6,RPL28,IFI16,DDX50,RPL6,WWP2,MAP3K14,DDRGK1,DDX23,RSBN1L,LHX2,DRG1,RPL8,RPL9,PHB1,SRSF1,RPLP2,LYAR,SYK,BET1,ZNF692,STAU1,NOP53,COIL,MYC,RAB11A,ZNF668,THAP7,FTSJ3,RHOB,DNAJB6,H1-1,NSA2,RPL37A,RPS9,RPL35,RPL7L1,FBXO22,RPL19,ESR2,RPL10 |
| 1.722e-05 | -10.97 | TMEM106B (transmembrane protein 106B) | protein interactions | 54664 | 307 | 120 | 19454 | 5460 |
EGFL7,RAB9A,HSPA5,CLU,PIP4P1,CHMP2B,LPAR1,CERS2,B2M,TMEM106A,TPT1,SLC35F6,MET,MEST,GP9,SSR1,HSP90B1,STOM,P3H1,GANAB,SEC61A1,GXYLT1,SEC63,TECR,TXNDC12,BUB3,CFL1,CNTNAP1,CTSD,CSK,CALU,ENDOD1,DNAJC10,TMEM106C,SDF2L1,TMX3,BSCL2,ERO1A,CTSC,GALNT2,TUSC3,L1CAM,TMEM33,SRPRB,ERLEC1,TP53,TOR3A,CCDC47,HSPA13,SURF4,STARD3NL,CHID1,XXYLT1,STT3A,GLT8D1,LMAN1,TMED9,LAMP3,DPP4,CALR,STYK1,P4HA2,TAPBP,TMEM106B,DNAJC3,ITGAV,STX7,GNB4,EMC1,EDEM3,CNPY3,AGTRAP,NOTCH2,TOR1AIP2,FAM3C,SLC25A3,HEXB,FKBP10,SIGMAR1,BST2,SLC30A7,PIGK,ATP6AP2,SPCS1,TOMM40,TMED4,TM9SF4,SERPINH1,ZMPSTE24,NTRK3,HSP90AA1,SPCS3,LAMTOR1,ERP29,PDIA6,SEC11A,MYO1B,GPAA1,TMED7,LGR4,ERLIN2,ACTN4,NCSTN,CCDC134,HEXA,EMC10,PLD3,STX12,RPN1,LANCL1,OS9,RMND1,VAMP7,TOR1B,ERLIN1,LAMP2,PDIA3,TMEM30A,CRTAP,AGR2 |
| 1.722e-05 | -10.97 | regulation of monoatomic ion transport | biological process | GO:0043269 | 466 | 179 | 18204 | 5365 |
MMP9,AHCYL1,BAX,ATP1B3,WWP2,HCRT,DPP10,CCL5,CXCL9,KCNC1,CASK,FGF12,PRNP,SNTA1,OXSR1,LILRB1,VDAC1,TRPC1,CA2,HTR2A,INPP5K,CCL3,YWHAH,KCNJ2,CAV3,GPR35,NDUFA4,FKBP1B,UCN,MIR210,EDNRA,HTR1A,CAV1,CLIC2,KCNAB1,MIR21,CD4,SELENON,LILRA2,MLLT6,CNKSR3,KCNIP3,MIR208A,NOS1AP,MRLN,TLR9,TF,KCNMB1,CXCL11,BAK1,TCAF2,CTNNB1,PACSIN3,MIR192,CAMK2G,CHP1,ABCB1,DRD3,ADRB2,AKT1,GSTM2,PPP3CA,MIR30D,CRHR1,SUMO1,MIR448,KCNIP2,PRKCE,CCR1,MCHR1,PCSK9,SLMAP,ACTN4,KCNS1,FKBP1A,CHRM1,MIR200C,PPP3R2,ATP2B4,CNR1,DLG1,SLC8A1,ATP1A2,ATP1B1,GNAI2,IL13,MIR34A,SESTD1,MIR1-1,P2RY12,HPCA,SCN1B,IFNG,RCVRN,CACNB2,TRIM27,LEP,APLNR,ATF4,PIK3CG,THY1,PDE4B,CRBN,PHB2,HOMER1,NETO1,PSEN2,ADORA1,STAC3,TMEM38B,KCNJ11,PLPP4,P2RY1,UBASH3B,FXYD6,B2M,SLC6A4,EPO,COX17,LGALS3,MIR153-1,STOM,MIR212,STIM1,OPRK1,HOMER3,GSTO1,AMIGO1,TSPO,LACRT,VMP1,ATP1A1,CD63,PRSS8,XCL1,SCN3B,KCNJ10,ISCU,MIR24-1,CACNB3,CX3CL1,STC1,HECW1,CAB39,CXCR4,MIR208B,TESC,TMBIM6,HFE,RAB11B,CXCL12,RANGRF,SRI,FGF13,PLP1,MIR424,KCNJ8,DRD1,CACNB4,ASIC2,PML,JPH4,TMSB4X,SPHK2,CCL2,VAMP2,NPSR1,NHERF1,CXCL10,PPIF,CCR2,F2,CNTN1,KCNJ3,G6PD,PLN,SCN2B,CFTR,DMPK |
| 1.726e-05 | -10.97 | AGO4 (argonaute RISC component 4) | protein interactions | 192670 | 108 | 51 | 19454 | 5460 |
SLC25A3,EIF4B,LEPR,STAMBP,WDR77,RPL27A,HSPA5,EEF1G,NF2,HSPA8,RPL27,HSP90AA1,RPS26,IGF2BP1,RPS5,TUFM,TYW3,HNRNPC,SLC25A1,TUBB,RPL35,ACTB,RPS9,TRIM24,PRMT5,SART3,PPME1,TUBB4B,IPO8,TNRC6C,PTS,CCT5,UTP25,PTGES3,ARF4,JAK1,TRIM21,SLC25A10,HSPD1,SLC25A5,DICER1,RPL23,RASSF8,RPL24,ECD,ANKMY2,PRDX1,HSP90AB1,DBT,AGK,SSBP1 |
| 1.726e-05 | -10.97 | SMNDC1 (survival motor neuron domain containing 1) | protein interactions | 10285 | 108 | 51 | 19454 | 5460 |
SF3B1,DDX46,SNRPA,COIL,SF3A1,ATG16L1,FDFT1,LMNA,SNRPD2,SF3B4,SNRPD1,ZNF330,SF3B6,SNRPB2,IDE,RACGAP1,SNRPB,CUL3,MYC,NFYA,RIT1,UBE2H,BRCA1,RPL3,EWSR1,PPAN,ABCF1,HSPD1,RUVBL1,KRAS,ANAPC13,RAF1,NAA35,SNRPE,SF3B5,SELENOF,SMNDC1,CAPZA2,CBX3,PHB1,SRSF1,DHX15,RBM42,SNRPD3,SNRPA1,FZR1,DDRGK1,RBM17,MOV10,PRPF19,CDK5RAP3 |
| 1.729e-05 | -10.97 | IK (IK cytokine) | protein interactions | 3550 | 192 | 81 | 19454 | 5460 |
TOP2B,ARGLU1,MRFAP1L1,SNIP1,RPL31,SRSF7,MRFAP1,SEPTIN7,TOLLIP,TRIM63,THRAP3,CTNNBL1,H3C1,TSSC4,G3BP1,RAB8B,SUPT5H,RPS7,NCSTN,IK,HDAC11,PDHA1,NUPR1,CERK,SNRPE,SRSF1,PPP2CB,TOP1,THOC1,WIF1,CDC5L,SRSF10,EGLN3,FRA10AC1,ZCCHC10,TRA2A,DDRGK1,XPO1,SNRNP70,DDX23,SIRT7,PML,NKAPD1,RPA3,RPL27,SNRPA,RNF113A,EP300,SQSTM1,ADGB,STAU1,UFL1,KDM1A,COIL,SAP18,MBD3,NUP62,ATG16L1,MND1,ZNF326,LSM2,RPA2,MFAP1,ZNF330,EZH1,EIF4A3,CCNF,PPP2R5E,SMU1,FBXO22,SNRNP40,NDN,ESR2,APEX1,SMARCA5,MYC,AR,CEP70,SNRPB,RIT1,UBE2H |
| 1.729e-05 | -10.97 | MED17 (mediator complex subunit 17) | protein interactions | 9440 | 192 | 81 | 19454 | 5460 |
ZCCHC10,CMSS1,BTF3L4,GTF2E1,MED29,MED27,MED21,HNRNPD,MED4,POLR2L,POLR2I,THOC1,MED9,TP53,SUPT5H,SMAD1,RPAP2,CDK8,BIRC5,POLR2G,POLR2C,PPME1,POLR2D,TRIP4,PPP1R12A,EMC2,VRK1,ROCK2,RBBP7,MRPS33,UTP25,RIGI,MED22,LMO2,MYC,CDC123,DRAP1,AR,CPSF2,RUNX1,BRCA1,ATG3,STN1,STK24,MED10,SMAD2,CMTR1,POLR2F,RPL35,ESR2,POLR2B,ROCK1,CBX5,GTF2H4,ATG16L1,UBLCP1,CDK7,EIF3J,FBXL19,MED30,SUPT3H,PICALM,HBB,RPA2,QRSL1,MED23,MED31,MTRES1,SUPT7L,TFIP11,FOS,STK26,MED13L,TCEA1,NR1I3,EXOSC4,ANAPC16,FBXW7,MED11,BCL6,CMAS |
| 1.737e-05 | -10.96 | regulation of mRNA metabolic process | biological process | GO:1903311 | 404 | 158 | 18204 | 5365 |
MOV10,MIR885,HSPA8,MIR340,CNOT8,NRDE2,SAP18,MIR190B,MIR26B,MIR140,HNRNPA2B1,SRSF12,NOVA1,TENT4A,POLR2G,HNRNPK,MIR130B,SF3B4,CARHSP1,MIR185,RNASEL,PCBP4,APEX1,TENT5D,HNRNPA1,MIR34B,MIR106B,THRAP3,MIR223,MIR135B,NCBP2,PAIP1,DDX5,AGO1,MIR142,MAGOHB,ROCK1,TRAF3IP2,MIR1-1,AHCYL1,SYNCRIP,MIR342,MIR106A,MYD88,ALKBH5,TIA1,MIR625,TRA2A,BTG2,MIR100,MIR193A,DCP2,MIR96,MIR30B,CDC73,MIR519D,RBFOX3,MIR146A,ARB2A,METTL14,RBM15B,MIR149,SNRNP70,MIR212,RBM3,RBFOX2,MIR181C,MIR204,MIR423,CNOT7,RC3H2,FASTKD5,MIR137,SRSF10,EXOSC3,CELF6,SRSF4,IREB2,UPF3B,YTHDF2,MIR195,MIR210,HNRNPL,AKT1,DHX9,DYRK1A,BOLL,MIR495,YTHDF1,ELAVL4,MIR23A,SRSF7,MIR211,PRMT5,PRDX6,MIR98,LARP4B,PRR5L,GTPBP1,EXOSC8,MIR24-1,SRSF2,WDR77,ROCK2,MIR192,RBM7,HMX2,SRPK2,WTAP,CNOT2,MAGOH,PDE12,CNOT6L,MIR9-1,HNRNPD,TNRC6C,TRAF2,MIR145,EIF4A3,MIR191,FXR2,MIR206,MIR373,PRKCA,MIR181D,MIR320A,MIR20A,CPEB1,MIR214,HNRNPA0,CIRBP,HNRNPAB,MIR497,VIP,CNOT6,RBM23,CASC3,MIRLET7C,MIR130A,MIRLET7B,CDK9,RBM42,MIR125A,RBM5,PRPF19,TIRAP,MIR708,MIR200C,TENT5C,IGF2BP1,PABPC1,MIR424,SMU1,HNRNPC,ZC3H14,MIR16-1,MIR491,TRA2B |
| 1.738e-05 | -10.96 | DYNC1H1 (dynein cytoplasmic 1 heavy chain 1) | protein interactions | 1778 | 429 | 160 | 19454 | 5460 |
TP53,ACTR1A,DISC1,TFCP2,RNF181,ILF2,MAP1B,HSD17B10,TOLLIP,HNRNPK,AKAP12,H3C1,DYNC1I1,CAPZA1,MEPCE,DPP4,NFKB1,HDAC6,COPS5,PSMD7,NME2,USP15,TSNAX,PTPN1,COQ8A,SYNCRIP,TES,TSR2,COX20,ARF6,CWC15,CDC5L,CCND1,SF3A1,SAP30BP,CFTR,RPA2,DCTN4,HEXIM1,SCLT1,OXSR1,PSEN2,SIRT7,RPA3,BAP1,SQSTM1,FBXW7,STK38,IRF7,GTF2I,BCL6,HSPA5,SLC25A1,USP14,AR,FBXO7,BICD2,TRIM23,SPOP,UBE2H,MAPRE1,SMAD2,NAPA,ATP1A1,CCNF,OPTN,RPS20,CSNK2B,PSMC5,ADRM1,RPGRIP1L,KCTD9,RAB14,VIRMA,DYNLT3,TOP3B,RAF1,MAX,TPD52,NUDCD3,ISG15,PPP2R1A,PDHA1,EZH2,TUBB4B,METTL21A,GLE1,MOB3C,RPS24,RUVBL2,MKLN1,HNRNPF,KRAS,G3BP1,PRPF19,PSMD3,CTNNB1,YWHAG,PSMD10,AGR2,HSPB1,YWHAB,DDX1,HNRNPD,PEX3,PHB1,PSMB5,SRSF1,TNIK,PCBP4,OSBP,SUMO2,SNRPD3,DYNC1I2,SNRPA1,HNRNPL,DHX15,EGLN3,PAFAH1B1,PSMB3,PPP1CB,PPT1,PSMB7,NCOA5,PIH1D1,EIF4B,XRCC5,SNRPA,AKAP1,RAB5A,SF3B1,HSPA8,MCMBP,HSCB,EMC1,SRSF2,CDSN,CUL3,MYC,SNRPB,BTF3,BRCA1,FBXW11,YWHAZ,HSP90AA1,RPS5,SP1,DLST,EIF3K,LMBR1L,SNRPD2,SF3B4,PRMT5,SNRPD1,DYNLL1,TSN,PSMD6,ACTB,MAD2L2,BTG3 |
| 1.740e-05 | -10.96 | human chr3q13.33 | chromosome location | human chr3q13.33 | 31 | 18 | 26134 | 5823 |
TMEM39A,COX17,POPDC2,EAF2,HCLS1,FSTL1,ILDR1,NDUFB4,NR1I2,CD80,RABL3,CD86,MIR198,TIMMDC1,ADPRH,CFAP91,SLC15A2,GTF2E1 |
| 1.748e-05 | -10.95 | RASD2 (RASD family member 2) | protein interactions | 23551 | 22 | 16 | 19454 | 5460 |
RABAC1,SMAD3,GNB3,GNB1,SMURF1,SMAD1,AKT1,TOP3B,RAF1,BMPR1B,PIK3R1,SMAD2,LRP6,ACVR1,SMAD4,PIK3CA |
| 1.750e-05 | -10.95 | NUP160 (nucleoporin 160) | protein interactions | 23279 | 172 | 74 | 19454 | 5460 |
ATG16L1,NUP62,OTULINL,SEC62,LMNA,SSR1,RPL26L1,LEMD3,RPA3,CD40,SIRT7,SNRK,EXD2,HSPA8,NUP50,DERL1,B9D2,DUSP26,TOMM20,MYC,CUL3,SEC13,USP14,LMNB1,RHOB,BRCA1,BICD2,EXOSC1,XPOT,RIT1,MAPRE1,CCNF,SCN2B,FOXP3,PTPMT1,SEC61B,PPP2R5E,VIRMA,ESR2,RAF1,COMTD1,TP53,RANBP1,NUP153,NUP37,CA14,EZH2,RPN1,SIGLECL1,CHMP4C,DISC1,NUPR1,SART3,TMT1A,G3BP1,NUP107,KRAS,TOLLIP,FKBP8,IFI16,EEIG1,SLC25A46,PTPN1,CTDSPL2,RAB35,RCHY1,HSD17B11,EED,STX5,SUMO2,TMPO,EGLN3,NUP35,CETN2 |
| 1.754e-05 | -10.95 | COX5B (cytochrome c oxidase subunit 5B) | protein interactions | 1329 | 141 | 63 | 19454 | 5460 |
CDK5,HSPD1,NUDT5,ATP2B4,BHLHE40,IMMP2L,FLOT1,LSM4,CHCHD2,APOO,PPIL3,PDHA1,NDUFS6,GATD3,RPLP2,AIFM1,COX7A1,PHB1,COX4I1,CDR2L,DBT,COX14,RMND1,SLC25A12,PLEKHF2,TEX12,DPP4,MOV10,COX5A,RAB5C,PSMD7,TMEM70,PDSS2,RTN4,DLAT,CDC42EP2,ATPAF2,VPS28,EMC1,PHB2,OIP5,YIPF5,TIMMDC1,TFIP11,CDR2,VAPB,COX7B2,TRIM27,PNMA1,UQCRC2,CCDC90B,TRAF1,PARL,ATP5F1B,TOMM40,ATP5F1A,AR,AUH,COX6B1,MCCD1,HTRA2,DNAJC19,TRIM23 |
| 1.754e-05 | -10.95 | ATP5IF1 (ATP synthase inhibitory factor subunit 1) | protein interactions | 93974 | 141 | 63 | 19454 | 5460 |
ATP5PD,SLC25A12,SURF6,SUMO2,MIF,NELL2,LHFPL4,GATD3,MRPS26,MED4,TMEM70,TIAM1,PPIB,RELL1,EI24,PDIA3,CALR,TAX1BP3,PGAM1,CYTH2,ANP32B,HNRNPK,PICK1,PDIA6,COX8A,ATP5PF,RPS23,PIK3CA,PDHA1,METTL15,ATP5PB,CSNK1E,TMEM101,ATP5F1B,THAP8,B4GALT3,TACO1,ATP5MC3,UBE2H,ARHGAP19,ARHGAP21,ATP5F1A,BFAR,TUFM,RNASET2,MTG2,PMPCA,CRYZ,CERS2,HMGB1,ATP5IF1,PGK1,ATP5F1E,VIPR1,SOD1,PEBP1,CAV2,MTRES1,ATP5PO,MED23,GPR35,FBXL19,CDC42 |
| 1.754e-05 | -10.95 | TXN2 (thioredoxin 2) | protein interactions | 25828 | 141 | 63 | 19454 | 5460 |
DDIT3,SAT1,TIFA,COX17,RABAC1,PTRHD1,SOD1,TFIP11,DCTD,CHMP1A,GABARAPL2,AGTRAP,SPTBN1,TOMM22,TXN,MRPL23,STUB1,REEP6,GTPBP2,BAX,STN1,TXNIP,CEP70,GPRASP3,AK3,MX2,SSNA1,RPIA,ZBTB14,GUK1,HINT1,COA4,TRIM21,MYO1B,MRFAP1,UQCC2,MRFAP1L1,CSTPP1,MSRB3,ILF2,GUCD1,MAGEA4,TTC32,NUDT19,TMEM205,THAP1,HADH,LYPLA1,CGGBP1,PRNP,LYRM2,MAPRE2,RPS16,FAHD1,RPL9,RPL8,SNRNP70,AK2,WDR12,GPRASP2,COX5A,MOV10,MDFI |
| 1.754e-05 | -10.95 | ABCB7 (ATP binding cassette subfamily B member 7) | protein interactions | 22 | 141 | 63 | 19454 | 5460 |
RHOB,CKB,DNAJC19,UBE2H,PMPCA,CUL3,AUH,MTG2,MAT2A,RAB2A,NDUFB6,TUFM,RHOJ,TAX1BP1,APEX1,VIRMA,ESR2,CCDC90B,CCNF,TACO1,ACAT1,FOXS1,MED23,RPA2,MTRES1,CFTR,UQCRC1,CDC42,MRPL10,SLC25A51,HSCB,RPA3,GFM1,AKAP1,PDCD1,TMEM70,RHOG,ATP6V1D,MTRF1,RHOH,RAMP3,EGLN3,PHB1,AIFM1,SSBP1,RAC2,GATD3,PDHA1,DISC1,AQP3,RPN1,TAF2,MRPL11,MTCH2,MGARP,FAF2,TGFBR2,KRAS,FKBP8,LTO1,NDUFA4,COX8A,HINT2 |
| 1.755e-05 | -10.95 | BIRC2 (baculoviral IAP repeat containing 2) | protein interactions | 329 | 224 | 92 | 19454 | 5460 |
ABHD17A,MAP3K3,ADRM1,UBE2L3,EAF2,TRAF1,OPTN,STUB1,TNFRSF1B,ZFAND6,IGF2BP1,TRIM32,TNFAIP3,TAS2R7,NTAQ1,FBXO7,CERS2,KDM1A,EIF4E,TOMM20,PML,MAVS,SQSTM1,VPS4B,JUP,HSP90B1,AKR7A2,UBE2W,CDC42,UBE2N,BCL10,BECN1,USP15,DNAJB2,XAF1,RNF115,CSE1L,TOLLIP,LTBR,DHX9,TLR3,UBE2B,ILF2,RNF181,BIRC5,TBK1,APOO,UBE2V1,TAX1BP1,CD40LG,UBE2V2,EFNA5,NFKBIA,UBE2S,GCC1,BOLA1,HTRA2,CUL3,CXCL1,RFC5,UBE2D3,BOLA2B,LYG2,TNFSF12,CD40,CXCL3,TIFA,BIRC2,MXD1,HBE1,TANK,PRDX3,PCSK9,EGLN3,PHB1,WDR82,DIPK2A,TSG101,UBE2D1,TRAF6,PPM1K,MAP3K14,TRIM34,TNF,OSTM1,GPSM3,GNAZ,RAF1,TRAF2,TULP3,CSTF2T,LGR4 |
| 1.760e-05 | -10.95 | ANXA6 (annexin A6) | protein interactions | 309 | 100 | 48 | 19454 | 5460 |
CHST11,CD4,MTAP,HNRNPL,SPPL3,PRNP,CGAS,POLE3,CAV1,RAF1,TPD52,H2AX,PLS3,EZH2,DNAJC2,PPME1,MOB3C,METTL18,S100B,EWSR1,IDH1,G3BP1,XPNPEP1,UBE2A,PAK6,RIGI,RPL7A,PDE4B,CHCHD4,NAPA,CDC73,UBE2H,CCNF,KCTD9,TUBB,SMURF1,VIRMA,LMNA,ADSS2,METTL14,PRKCA,SHOC2,RHOU,RPA3,SIRT7,HSPA8,CERS2,OXCT1 |
| 1.790e-05 | -10.93 | LAMP3 (lysosomal associated membrane protein 3) | protein interactions | 27074 | 485 | 178 | 19454 | 5460 |
DHRS7B,KRIT1,SEC14L1,SLC29A1,CCDC47,CTNND1,SNAP23,SEPTIN7,DLG1,STX8,RAB1A,SLC25A10,NSDHL,ESYT1,SLC2A1,RAB23,RAB22A,RELL1,TMEM199,CAV1,ARF6,CDCA3,ARL10,PTPN1,SRPRA,PICALM,GOLGA5,SLC12A2,CTDSP1,CNP,COMMD3,ARHGAP1,SEC22B,RABL3,ATG4C,YKT6,SLC7A1,SPCS2,ITGA2,EPHA2,ARFGAP3,PPP1CC,HMOX2,RHOBTB3,DEPDC1B,VKORC1L1,FERMT2,YES1,SNX3,RAB14,SFXN2,SLC11A2,SNX12,SCAMP2,SMAP2,VAMP3,UCKL1,STX12,VAMP2,VPS33A,STIM1,RPN1,TULP3,DSTYK,FAF2,MARCKSL1,MACO1,JAK1,SCYL2,SLC20A1,MARCHF5,PRKCQ,SNX1,SNX2,OCRL,GJA1,WDR6,VAPB,ABCB1,RAB6A,PGRMC1,NOTCH2,TOR1AIP2,STX7,COMMD2,CLDN1,SLC35F2,UPF3B,ATP2C1,VMP1,SCFD1,LMNB1,RAB11A,VEZT,MAD2L2,CHCHD3,GPR89A,AP2M1,SLC30A7,ARF1,EXOC3,TFRC,METTL15,UBIAD1,SNAP29,SLC25A14,FKBP8,SLC6A8,RAB3B,AKAP12,YIF1A,GALNT12,RAB13,DHRS7,LMAN1,RAB39B,SLC38A2,STX6,TMPO,FCHO2,ARL6IP5,VTI1B,ATP8A1,SLC39A10,CAMLG,LEMD3,CSNK1G3,UTP15,GALNT4,SPTBN1,RAB9A,ARFIP1,UGDH,SNX5,ATP1A1,NCAPG2,GORASP2,SLC6A6,KCNQ5,RAB2A,SRC,ROCK1,STX10,PRSS8,NECTIN2,TUBA1A,SNAPIN,ARFGEF1,STBD1,VAMP8,SLC20A2,ROCK2,EFNB1,TMEM87A,DDRGK1,SLC38A9,PPFIBP1,PTDSS1,TMEM97,VAMP7,RAB1B,STX5,NEK7,BORCS6,BET1,RER1,RAP2A,TMEM106B,SLC38A1,RPS6KA4,LAMTOR1,RALGAPA2,SLC30A5,SLC1A3,TMEM38B,ATP6AP2,TAMM41,FAM83B |
| 1.794e-05 | -10.93 | cellular response to organonitrogen compound | biological process | GO:0071417 | 505 | 192 | 18204 | 5365 |
OPRM1,SLC1A3,AKT2,INPP5K,CA2,HTR2A,SFRP1,CSK,AHCYL1,IGF1R,MIR107,BGLAP,GNAQ,GNAO1,SOCS2,SLC2A8,MIR106B,YWHAG,MIR200A,EPHA4,SOS2,DEFB124,ATP1A3,SELENON,IDE,PSEN1,MIR146A,TLR9,PLCB1,PCK2,GABRB2,GNRHR2,BRCA1,JAK1,CD36,CIB2,MEF2C,LDOC1,STAMBPL1,CAV3,PAX6,SIN3A,CAV1,HTR1A,WNT10B,EDNRA,STAT6,FOLR2,TLR6,SULT1A3,ADRB2,DRD3,SELENOS,GRB10,GCLC,P2RY4,PTPN22,TBC1D4,GSTM2,AKT1,SESN3,CTNNB1,GH1,SLC1A1,GJB2,NPR2,GABRG2,MAP1B,AGTRAP,SLC1A2,AANAT,GPT,IGF1,EP300,UCP2,PIK3R3,NSG1,SLC8A1,RAB13,NCOA5,XBP1,GRIA1,CPEB1,CTNNA1,SOX9,HDAC5,GNA14,SHC1,GSK3A,CRHR1,RAP1B,BCL2L1,JAK2,EIF4EBP2,STAT1,KDM1A,PCSK9,CAV2,KLF4,BACE1,MIR140,PIK3CG,INSIG2,TLR4,LEP,P2RY1,TSHR,MGARP,TMEM38B,CSH1,COMT,PTPN1,GHR,CALY,SRC,GNG2,HPCA,P2RY12,GPR173,CAMP,MIR143,PIK3CA,MDM2,GNAI3,ICAM1,TP53,SP1,PPARG,CCNA2,SHOC2,RPL23,KLHL22,PIK3R1,GAB1,PIK3R2,JUP,SESN2,AMIGO1,CHMP5,NCSTN,EZH2,NR4A2,NFE2L2,SLC6A4,EGR1,MECP2,MIR98,FCGR2B,CXCR4,FBP1,AGER,HRAS,TOP2B,GABRB3,GNB1,CDK5,HNRNPD,CRHBP,RAP1A,MIR145,PPP1R1B,STC1,CYP11B2,ACTB,SHMT1,TNF,ADIPOQ,RAF1,P2RY11,FOXC2,STAT5A,CFTR,GJA1,RARRES2,CASTOR2,CYP1B1,CASP4,PTGER1,NFKB1,DRD1,RAB31,SLC22A12,CYP11B1,RB1,GNA11,NPPC,FOLR1,NHERF1,VAMP2,FOS,HSP90B1,PDE2A |
| 1.794e-05 | -10.93 | extracellular region | cellular component | GO:0005576 | 4350 | 1374 | 19108 | 5553 |
SNAP23,RLN3,HAPLN2,TXNRD1,CTNNB1,MIR204,SNAPIN,CDC37L1,VEGFC,FCMR,NPVF,ESD,MIR454,AP2M1,PPFIA2,IFT172,PATE4,GPX4,ARHGAP1,MICB,VPS4A,REN,PMP2,MIR100,RAC2,TOM1,AOX1,RPL23A,CTSC,CNPY4,STAU1,PPY,DDT,H2AC13,MIR505,DDR1,CCL17,RPS20,DNPH1,SELENOS,MIR99A,H3C1,LCP1,PGAM1,EPCAM,CASP4,RNASE1,YWHAH,LEAP2,MBD5,CHI3L1,MIR340,CMTM7,MIR1296,NXPE3,NDFIP1,BPGM,DEFB121,FGFBP2,PI15,MME,ZBTB38,ROCK1,NUDT1,EIF2S1,SCN1B,MIR425,IL1RAP,TPT1,BPIFB4,CXCL12,F2,MIR192,DEFB129,GNPTG,NDNF,EIF4E,RHOB,LEP,SYT4,HMGB1,PLAA,NECTIN2,DDAH2,GLE1,KRIT1,SPATA6,TMSB4X,HBEGF,PROM1,SEMA3C,PPP2R1A,CDK1,GPX3,PSMD6,MTAP,MIR194-1,RPS29,IFI35,PSORS1C2,SVIP,NAA50,AKR7A2,NRN1,EIF3E,AKR1B1,SLC25A3,C1QTNF1,SPOCK1,MIR590,CTSK,TMEM256,LCN15,S100A11,CHMP5,PPT1,MIR502,COMMD3,CNP,LILRB4,FBP1,CLCA1,CD63,CLIC4,PRCP,ENO2,MIR210,SSBP1,NME1,COL3A1,CYFIP2,MIR101-1,RPS9,CACYBP,CKB,PTH2,VSTM2A,ADPRH,PEBP4,TMBIM1,TNFSF13,PDYN,KRT8,JCHAIN,RHEB,GLO1,MIR335,MAMDC2,SOD1,NOG,DLG3,GSTCD,APOC2,LYPD6,FAM151B,ACTR3B,PITPNA,MIR3173,PRSS8,CDH8,TMED9,ADSS2,SNRPD2,UBE2D3,STOM,GNAQ,RPS14,VAMP8,ODAM,SCGB1D1,VASH1,PALS2,MIR1249,GSTP1,SPRN,B4GALT4,SPINK9,NCKAP1,FLRT3,HAS3,RAP1B,TOR3A,SPON1,AKR1C1,PSMB4,DKK3,KARS1,USP14,IRAK4,MIR208A,HEBP2,ZNF177,CBR3,TNFAIP6,PMPCA,CSRP1,GCA,PEBP1,SFN,PNP,MIR106A,ARPC2,MIR144,VAMP7,RPL3,PAFAH1B1,ARPC3,SLC16A1,AIF1L,LDHB,RAB6A,C1QC,CD209,THBD,LRRC3B,STK26,TMT1A,RPL39,CFC1,ATP5F1A,DUSP26,PSMA2,RAB11B,SCPEP1,LCN9,S100A6,PSMD1,GMPPA,NPY,RPS4X,CD99L2,OLA1,IGF1,RAB11A,RUVBL1,TUBB,FUT8,NPC2,EEF1A1,COMT,MIR619,MIR215,IL5,PRNP,CAB39,NEDD8,PABPC1,TIMM8B,MOXD1,TCP1,MIR384,EPS8,ST8SIA4,MIRLET7G,FGF1,PTGDS,PBLD,ITGB5,KLK5,HBA1,PSME2,TFRC,ILF2,IDE,CCL1,RPL27,ANGPTL2,SRSF7,LGALS8,MIR186,NINJ1,GDPD3,TGFBR2,GAPDH,ANGPT1,FGL2,PDIA3,FMOD,TGFB3,CNTFR,MIR139,CDNF,SRP14,PAFAH1B2,IL13,GLIPR1,DBH,DHRS13,ABCB1,METTL24,CDH13,GAS8,CCL4L1,PYCARD,GGCT,CXCL13,RPS26,MZB1,MIR877,FCN2,MIR20A,AMELX,HIRA,PSMC3,FBP2,NTN4,CYBRD1,NGRN,LRP6,CCT2,CREG2,RUSC2,RAB5A,VSTM4,NLRP3,CD52,ADGRG1,RHOJ,FAH,GNB3,RPL37A,UCN,SCG3,GCNT3,MIF,BST2,HEXB,FLRT2,AQP4,FAF2,CEACAM5,IL3,PTN,GNG12,GALNT1,F7,ATP6V1C1,PSMB1,FGF17,RPSA,H2AC7,WNT2,ALKAL1,MIR1234,CSTB,SFT2D2,HNRNPL,RLN2,PTPRZ1,PGRMC1,SERPINA5,MIR25,ARL15,CXCL10,CKLF,CHMP2A,RAB9A,YPEL5,UBE2N,SERPINB10,STX1A,MIR141,CYTL1,HBE1,UTS2,GPC4,ACSL4,RALA,ARF1,GNB1,MIR769,SLC20A2,MIR30D,LGI3,PDCD5,MIR421,NUDT9,PADI2,TIMP3,IL12A,LECT2,AKR1A1,LAMTOR1,GANAB,PEG10,MIR98,CX3CL1,CHMP2B,ALDH1A3,RPS5,KLK3,CSH1,CD40LG,ATP1A1,HILPDA,DEFB115,TAX1BP1,EXTL2,UBE2V2,ATP6V1D,MYL12B,BAX,RNASE4,NAPA,MIR15A,SFTPD,GRID1,MIR191,HEBP1,MIR424,RAN,FKTN,LILRA2,HSPA13,PLAC9,LYZL4,CFL2,CAPG,EGFL8,GNPDA1,H2AC6,PRDX1,ACTA2,UGP2,TNFAIP3,MARCKSL1,PDIA6,WNT7A,CTSB,CRISP1,LYZ,CD1D,GSTT2B,LY6G6C,PPIC,GNG5,CYB5D2,MIR589,SELENOP,RALB,TRAPPC1,IDH1,HSP90AA1,CCL2,RPS11,MYO6,PGM1,GPM6A,PLA2G12A,PDCD1LG2,RHCG,AGER,IFNB1,PGA4,NELL2,MYO1B,MBL2,RAB1A,MIRLET7D,RUVBL2,H2BC11,VSTM2L,CXCL14,CST11,SEPTIN7,NEU1,CDSN,EPHB6,B2M,OLR1,SPTAN1,ISG15,CHMP1B,ACHE,CHID1,SOSTDC1,TIMP4,GABBR1,HFE,MIR182,SAMM50,PTEN,ABHD8,MIR185,RPS27A,OLFM3,CXCL3,CCN3,CCT8,RNASE6,MTMR2,WNT10B,PSMB6,UBB,CTSA,AGR2,IL15RA,DPP4,MIR652,CER1,GNB4,RS1,OVGP1,ELFN1,VTA1,COL1A2,ALB,CTSD,GPT,RPL4,MIR140,REG1B,RPS2,RAB19,RAB8B,SERPIND1,LILRA3,MIR375,MMP9,KIF3B,MAT2B,CCDC3,FSTL1,GFOD2,CRYL1,F10,CRTC2,RAB13,SCAMP2,ALDH1L1,MSMP,SEMG2,RACGAP1,MIR493,PLA2G4B,MIR148B,MACROH2A1,STXBP1,PSMA4,MIR370,H2AC1,SLC22A6,TAX1BP3,KLK9,GDI2,HTRA1,FGF10,MATN4,GZMK,MIR671,ARF6,MIR320A,RPL22,SLPI,CCL8,ACTB,CES5A,SLITRK1,SEMA5A,TOR4A,BPIFA3,MIR145,DNM2,ERO1A,CAND1,LRRTM2,CCL19,FURIN,HSP90AB1,GALNT2,PGK1,SDCBP,XRCC5,GSTT1,HSPA5,H2BC9,PSMB2,ADM2,RARRES2,MIR30B,IL18BP,PTGFR,FGFBP1,RBP5,TULP3,SIAE,FGR,WASL,PI3,RPL23,HP,HSPB1,GNA14,PRL,RPE,CCL23,MIR223,GHRL,MIR181D,GSTO1,LYZL6,MIRLET7I,MIR214,EDDM3B,GFUS,CPXM1,LCN6,VMO1,COCH,CHP1,MET,LILRB1,TNFSF18,TUBA1A,SYPL1,NDP,SELL,PCBD1,LY6G5C,XPNPEP1,PROK1,F9,RAB3B,SMURF1,MTRNR2L7,LDLR,PSMD14,RPL35A,ELFN2,CD274,SPTBN1,EMC10,H2AZ1,CCDC134,C1QL3,PLA2G15,PRDX4,CARTPT,TNFSF10,BLVRA,SUB1,PLAC1,SERPINB11,ANXA7,EEF2,MYL12A,ARL6,SFTPA1,COTL1,VEGFA,DNAJC7,TOMM70,HNMT,IL1A,MT3,EFNB1,TNR,GRIA1,MSN,LAMTOR3,MLN,CAPN2,CCL24,MIR21,DSTN,RPL28,GPX6,RAB14,GLOD4,MIR1-1,CNDP2,CD9,CCL25,UBXN6,CD2,CD79B,FTL,H2AJ,GPC1,TEX264,ST3GAL2,PHB1,MIR503,IL1R2,CAPZA2,BPIFB3,FAM3A,WFDC5,SH3BGRL,RPL26L1,ATP6AP2,MIR4446,INA,HNRNPC,GLIPR2,MIR34A,IFNG,CSNK2B,PSMB9,EGFL7,NFKB1,HSPA8,APLN,MDH1,BMP1,PI16,SCGB1C1,TTR,MIR148A,CD38,MYL6,STC1,RPLP2,FGFR1,H2BC14,MIRLET7C,PLEKHO2,GOLGA7,PSMB5,ZMPSTE24,FABP4,GNA11,GAL3ST4,FLOT1,TSPAN3,TSG101,KRT7,CD200R1,RPS28,B4GALT3,BGLAP,RAB4A,NPW,PCSK2,CAPZA1,MGAT1,MIR198,C9orf72,VLDLR,AP1M1,ST13,SNX18,TOM1L2,CCL5,S100A8,CYB5R1,FGF7,PSMD3,MIR378A,DIPK2A,PPIA,MIR183,GREM1,CBLN2,PSMA1,NRP1,ALPL,CAMP,RRAS2,MIR10B,FAM3C,WWP2,NOTCH2,GFOD1,APOO,SPP1,CD1B,CUL3,MIR338,CSE1L,MIR130A,CALR,CMBL,SERPINH1,RPLP0,IL6,SIT1,FAS,MIR10A,MIR181C,MIR638,ST6GAL1,ATP1A3,GABRB2,RNASET2,RAB22A,SVBP,FGF23,IL23A,SCG5,APOC4,AHSA1,YWHAB,IRF2BPL,LMAN1,TGFB2,AZGP1,CXCL11,CBLN4,VDAC1,MIR26B,CALU,SST,GNL1,PAEP,TNF,TIMP1,GMDS,WWP1,HBB,OAS1,FTH1,AASDHPPT,CELA3B,OXSR1,CBLN3,IRF6,ENHO,HUWE1,PPIB,SNX3,MIR125A,OAZ3,IFNA10,RHOG,FGF16,BLOC1S5,NME2,GPHA2,MBLAC2,TF,MIR937,VPS4B,FGF12,MIR23A,GSTK1,IL10,IL21,CXCL9,PRKACB,CD248,DEFB114,STK11,IGIP,RAB2A,GALNT4,ACAT1,LCN8,SERPINB1,ICAM3,CD34,ZBED3,GPX7,TUBB4B,GNRH1,MIR16-1,MIR423,TXN,CDC42,SLC2A3,TPSG1,SERPINI1,PSMA6,SNCG,MIR146A,IFNA2,ST3GAL4,YWHAG,IGFBP4,GSTA2,OLFML3,C1GALT1C1,RAB29,AK2,ACP2,MIR92B,WIF1,ADAMTS20,PDCD10,MIR106B,ADAMTS1,ATP1B3,CRYAB,RPL26,CALML5,CTNND1,MIR29C,TUFM,APEH,TOR1B,EMILIN3,H2AC25,TAGLN2,PCYOX1L,PLCB1,FABP5,GNAI2,CFAP20,TWSG1,RAB3D,LRRTM1,MIR222,MIR17,CSK,LY96,MIR532,GNG2,SOD2,PRND,PRDX2,HNRNPA1,PCNA,LAP3,CD58,HSPD1,LEPR,RNASE9,MIR152,CCL28,CPE,FAM234A,BPIFA2,LGALS3,KDSR,THY1,RPS13,MIR24-1,PLA2G5,SRI,MIR361,TST,THRAP3,ZNHIT6,SERPINB6,PDZK1IP1,PRSS1,MIR126,SLC12A2,PSME1,PNOC,CHST9,LHB,GSTM3,PRSS12,CD36,PTHLH,AQP2,LGI1,NCR3LG1,MIR24-2,STAMBP,ANXA4,CTRB2,GK2,LYG2,GSTA1,MPST,NAA16,GSTO2,MIR30E,SPINK13,ART5,MIR142,BTG2,SFRP1,CD81,BPIFB1,DPEP1,LUM,MIR132,MIR29A,SERPINA3,PACSIN3,DNAJC3,PYGM,CCL20,PRELP,ACTR2,CXCL8,MIR150,ADNP,GBE1,RNF11,CPNE2,EHD1,COMMD9,B4GAT1,SLC15A2,MRPL18,CCT5,LRRC24,FKBP4,FAM168B,SH3BP4,SOD3,NCSTN,GHR,CXCL1,OGN,KLK6,LYPLA2,VAMP5,DEFB1,IFNK,GPIHBP1,UPK1A,CCT7,SHMT1,SPAG11B,PRDX6,MGAT4A,ATP1A2,NETO1,PPP1CB,PRRC2A,IL22,AGGF1,ATXN10,ATP1B1,IL34,IL7,HINT1,RALGAPA2,GTPBP2,LAMP2,CCL21,TXNDC17,NTNG2,ELSPBP1,SEMA4C,ENO1,GHITM,RAB5C,HNRNPK,RHOBTB3,PRKCB,RAB35,CHCHD3,TLR9,NPTX1,MMP28,ENDOD1,SORD,LTA,MIR16-2,IGFBP3,PSMD12,MSTN,DES,AMY2B,LYPLA1,LXN,ATP6V1G1,SLC1A1,PSMD7,LAT2,SRC,PATE2,LDHA,CRYZ,DDX23,FRZB,ABHD14B,PLD3,CD1A,MAN1A2,NTF4,MIR205,SEC13,MIR23B,MIRLET7B,PRRG1,IL6ST,TLR3,CA2,RAB27A,ENPEP,FASLG,FCAR,CXCR4,GNAI3,RARS1,TOM1L1,PDE8A,SFTPC,MIR197,LAMB2,TNFRSF1B,EEF1G,VWF,SFRP4,CD47,MIR625,CAPN1,MIR193A,CUTA,PSMB7,SLC35F6,TNFSF15,PLAC8,CRTAP,ANP32B,MOV10,VPS28,TFPI,MSMB,SLC22A12,MIR9-1,CCL18,CD1E,SRGN,OTOS,ALYREF,CMA1,GGH,FOLR2,YES1,MIR339,CBLN1,MIR99B,CHMP1A,CTDSP1,H2AZ2,DEFB116,NIBAN2,WASF3,DLG1,TNFSF12,LCN1,F11R,GSTM2,IL4,PRKCA,CD14,ARF4,GLUL,DAG1,MMP20,RPL31,IZUMO1R,TNIK,ACTR1A,STK24,MIR342,CD1C,GPX5,CRB3,PPFIA3,PDAP1,PLG,CRHBP,ICAM1,GPRASP3,LCN12,ATP6V1A,RPL12,DNAJB9,G6PD,CRYM,OSM,UBE2V1,PRSS35,GFPT1,FAM20C,SLC2A1,NCOA5,PSMC5,TMEM59,CMPK1,MEST,ITGAV,RAP2B,YWHAZ,ST3GAL1,SLC22A8,C1QL2,EMILIN1,HHIP,SQSTM1,CLTRN,CD86,H2AC4,DHRS11,BMPR2,SCG2,IL15,XCL1,IL2,MGP,P3H1,IL1B,DNASE1L1,FKRP,S100A10,CRABP2,DKK1,MAGED2,SLC25A1,CHRDL1,DEFB124,SLC11A2,FGF22,RPL24,FIBIN,CDH11,MIR422A,CSTA,NAPG,PYGB,NEGR1,CHGA,FKBPL,SRPRA,ACO1,TOLLIP,CD2AP,ATG7,ADIPOQ,H2AX,FGF3,GNG7,HEXA,FBLN5,PCSK9,CPNE1,DICER1,IL18,UGDH,IDH2,ATP8A1,TAC1,IL12B,CCL3,AGAP2,RAB3A,MIR628,TPM3,ECRG4,SERPINC1,HSPB6,SLC38A1,PLSCR1,WFDC13,IL17F,CSF2,RAB1B,GREM2,ITGB8,MIR136,NPB,PRSS23,SERPINB9,MIR636,RP2,KIT,MIR301A,MIR374A,ACTR1B,CIB2,DDAH1,NMI,MIR221,DDX5,CD40,HSPE1,EHD4,TSPO,MIR331,MIR28,BRINP2,OLFM2,NLGN1,THBS3,CCDC126,TNFSF8,PSMB3,MIR130B,CFL1,UBA52,AHCYL1,EPO,JUP,AGA,NXPH3,CD59,REG1A,RPS3,DSN1,ALCAM,ADAMTS10,FOLR1,SPINT2,MIR874,BRINP3,SPR,ENPP4,ACTN4,CLU,HNRNPA2B1,MECP2,RAP2C,VTI1B,MTRNR2L3,MIR143,CYB5R3,NUDT5,ITM2B,MIR31,SAT2,ARMC8,RAP1A,SERPINA1,PRSS37,LRRN1,PIP4K2C,LTB,CYRIB,SYNGR2,NHERF1,MIR1304,NPPC,PSMA3,PABPC1L,INHA,PROS1,ICOS,RPS16,H2BC12,MIR484,CCL27,MARS1,SDC4,UBL3,HCRT,LRRTM3,C1QL1,GLRX,CCL11,LRRC57,MIR500A,MIR193B,VIP,CST3,RETN,LACRT,CD46,IFNA13,CD164,HGS,CYSTM1,MIR212,B4GALT1,S100B,IZUMO4,MACROH2A2,TAFA1,MIR363,SOST,MIR107,MMP14,CNTN1,MIR30A,GH1,LY6H,STX7,PSMA5,RPL10A,CLEC18A,HSP90B1,MIR345,ATP5F1B,GNRH2,ANKH,FAU |
| 1.799e-05 | -10.93 | SUMO2 (small ubiquitin like modifier 2) | protein interactions | 6613 | 579 | 208 | 19454 | 5460 |
PDCD4,UBE2H,CARS1,MYG1,TRAF1,RPS3,ZBTB33,CSNK2B,PSMC5,HPS6,RPRD1B,SPTBN1,GTF3C4,KDM1A,MARS1,HSPA5,NBN,PML,HNRNPH2,PGK1,PRDX6,SMCHD1,MAP4,KARS1,PGAM1,TPM3,MIF,TMPO,SYNCRIP,CHAMP1,NFE2L2,NUPR1,RNF8,PSMC3,RRM1,TP53,ZMYM3,ZMYM4,NUP107,CSE1L,KPNA2,HNRNPK,ZNF451,ZBTB25,RPL3,CKB,CCT2,MAF1,MYC,ZMAT3,CPSF2,TAGLN2,ZCCHC7,RPL10,NFKBIA,ZMYM2,ANAPC2,TANK,NEK7,HNRNPA0,EEF1G,SERPINB6,MSX1,DDX39B,RFC4,PEBP1,FOS,XRCC5,HSPA8,SF3B1,EP300,DDX5,DDX1,HSPB1,YWHAB,BAZ1B,PPIB,XPO1,YWHAG,HNRNPL,TCP1,SUMO2,SUMO3,HSP90AB1,SIN3A,FABP5,GYS1,ZHX1,TUBB4B,MTA2,TRMT1L,SUPT5H,SOX2,EEF2,KIF2A,HNRNPF,ZBED1,KRAS,RUVBL1,XPNPEP1,RPS4X,TOP2B,ABCF1,EWSR1,ZCCHC12,PPP1CC,NONO,AR,UBB,PELP1,EIF2AK2,ENO1,TUBA1B,TRIM24,UBE2I,SENP5,LMNA,HSP90B1,RARS1,SF3A1,PSMC4,ATG16L1,SPR,GTF2I,IRF7,RPL4,SMC4,PIAS1,SOD1,CALR,CAV1,ZBTB2,ETV6,SEC23A,TOPORS,TBK1,CCT5,DDX39A,EEF1A1,CTNNBL1,SEM1,HUWE1,HSPE1,TRIM63,CTNND1,ARF4,RNF20,MDC1,MSH6,EHD4,ZC3H11A,HSD17B10,BRCA1,HSP90AA1,SP1,ILK,ACO2,NIBAN2,HNF1B,CUL3,SAMHD1,RFC5,MCM4,MCM3,GGH,EIF4A2,RBBP4,UMPS,TUBB,ACTB,USP5,BAD,ELK3,RAN,ENO2,PRDX3,CMTM6,ZBTB39,PSMC1,ATP5IF1,EMG1,PDIA3,NOP58,SPTAN1,CCAR2,EGLN3,IGBP1,XPO5,HP1BP3,SDHAF2,KRT8,EZH2,CTSA,SOBP,ANP32A,JUN,NUP153,PPP2R1A,TRIM26,RBBP7,S100A10,SSRP1,AHCYL1,ANP32B,RAD21,RFC2,HSPD1,HNRNPA2B1 |
| 1.801e-05 | -10.92 | NAPG (NSF attachment protein gamma) | protein interactions | 8774 | 79 | 40 | 19454 | 5460 |
STX12,USE1,VAMP2,RPA2,PTP4A2,BET1,SEC22B,SNAP29,VAMP8,STX7,FBXW7,GPM6A,YKT6,HSPA8,STX18,STX8,RPA3,HAX1,SCFD1,NAPA,LSM6,STXBP6,TUBG1,STX16,BTF3L4,PRKACB,VAMP5,NUDT1,MDFI,RABIF,VAMP7,STX6,VTI1B,ODR4,STX10,STX5,TYMS,FAM177A1,VAMP3,FAIM |
| 1.804e-05 | -10.92 | YIPF5 (Yip1 domain family member 5) | protein interactions | 81555 | 130 | 59 | 19454 | 5460 |
SLC2A1,RHOG,ESYT1,TAF9,EI24,FAM20C,RAB5C,RAB1B,EGLN3,CAV1,CD63,PHB1,SEC23A,RAC2,MACO1,TP53,MGARP,FAF2,TMED7,HS2ST1,RAB18,RAB1A,ATP5PF,YIF1A,PSMD14,NAPA,ATP1A1,SCFD1,UBE2H,COX6B1,TMED5,RAB2A,TMED4,ATP5F1A,ATP5F1B,ESR2,S1PR4,CCNF,CYB5R3,SLC30A7,RETREG3,SLC1A1,MSN,ATP5PO,TMEM115,GPR35,RABL3,PTAR1,SEC62,SEC22A,HSCB,ADRB2,PHB2,SSR3,RER1,ATP2C1,TSPAN15,VIPR1,RABAC1 |
| 1.804e-05 | -10.92 | CDKN2AIP (CDKN2A interacting protein) | protein interactions | 55602 | 130 | 59 | 19454 | 5460 |
HNRNPA1,XPO1,CLP1,KPNA1,PRR3,ADD1,SSU72,CDC5L,MRPS23,MDM2,POLR2I,KCTD10,PAIP1,FAF2,TP53,E2F4,MAGEB10,SART3,MOB3C,RPS11,RPL3,FGF3,HSPD1,S100B,HNRNPDL,MDC1,UTP25,RAD21,RPL28,HNRNPF,MRPS33,GGH,RUNX1,PRKACB,CUL3,MYC,COL1A2,ELAVL2,BRCA1,CHAC2,PRKRA,ESR2,FBXO22,SNRNP40,MATR3,RBMS2,CCL3,ATG16L1,MACROH2A2,EPHX1,ZNF574,SLC12A2,APOBEC3C,RPA2,PAK2,ATP5PO,RNF113A,RPA3,HSPA5 |
| 1.814e-05 | -10.92 | MBOAT7 (membrane bound O-acyltransferase domain containing 7) | protein interactions | 79143 | 175 | 75 | 19454 | 5460 |
SLC7A1,EMC1,LPAR1,RPA3,PML,TSPAN15,HSPA8,RAB9A,RNF113A,RPA2,SSR1,COX7B2,STOM,TPRA1,SEC62,CDC42,OTULINL,RND2,YIPF5,ST7,RHOJ,APLNR,GPR37,CLRN2,ACAP2,SEC63,APEX1,ESR2,S1PR4,LMBR1L,EDNRA,SEC61B,SYP,LMNB1,MYC,TM4SF20,TM2D2,RAB11A,CIAO1,KRAS,STX8,TMT1A,ATP5PF,ADRA1A,SPTSSA,LRRN4CL,EMC2,RPN1,SIGLECL1,EZH2,STIM1,CRELD1,CYB5B,PTGFR,CCDC47,LBR,DNAJC25,ARF6,RHOH,COX4I1,HSD17B11,LMBRD1,RAC2,STARD3NL,RHOG,ESYT1,UPK1A,CD36,LAMP2,CD200R1,FAM20C,RAB5C,SLC35A5,LAMP3,HM13 |
| 1.814e-05 | -10.92 | NIF3L1 (NGG1 interacting factor 3 like 1) | protein interactions | 60491 | 175 | 75 | 19454 | 5460 |
PNMA1,SULT1A3,QNG1,PAFAH1B3,EIF4A3,CYRIB,TRIM27,KCTD9,TXN,LAMTOR3,YES1,TOM1L1,DYNLT3,APEX1,ACP2,LMO2,DHPS,CDKN2D,CCDC85B,PCBD1,NIF3L1,OSGEP,CALU,RPA3,RABAC1,TIFA,SAT1,RAMAC,PPIH,ARPC2,SQSTM1,FXR2,COIL,GRPEL1,VPS28,LAP3,SPMIP6,LMO3,RPRD1B,ZNF326,EIF4B,DCTD,PPP2CB,TSG101,SH2D1A,COPS2,NT5DC1,MAPRE2,PRNP,EPHB6,KXD1,ORC5,PFDN5,EIF5A2,SSX2IP,PALM2AKAP2,ALKBH4,RBM3,CDKN2C,TRIM21,ZBED1,KCTD17,RPIA,DCTPP1,GNMT,EIF2D,TRAF2,UBXN2B,CCS,SPG21,NGB,ACTR2,NME1,SH3GLB1,STK16 |
| 1.814e-05 | -10.92 | ABCF1 (ATP binding cassette subfamily F member 1) | protein interactions | 23 | 175 | 75 | 19454 | 5460 |
B3GNT2,FBP1,TRIM6,TP53,E2F4,ILF2,RNF8,NUPR1,DNAJC2,CHMP4C,SMNDC1,ABCE1,EMC2,DHX9,RTCB,HNRNPA2B1,TICAM1,RIGI,KRAS,ATG7,COPS5,XPO1,DDRGK1,IFI16,WWP2,DDX1,POU5F1,BRD3,SNRNP70,AGR2,PSMD7,TRAF6,NCK1,EED,H2AZ1,PHB1,RCHY1,FZR1,SPPL3,DYNC1I2,EIF2B2,SUMO2,CCDC181,PAAF1,RPL27A,SYK,PIH1D1,RPA2,METTL14,MAP2K1,EIF2B3,EP300,RNF113A,BAP1,RFC4,RPA3,SIRT7,HNRNPA0,UFL1,FBXW7,H2BC9,MYC,CUL2,SUB1,IRF6,RIT1,UBE2H,PSMC5,RTRAF,CCNF,CMTR1,VIRMA,MATR3,RPGRIP1L,FBXO22 |
| 1.821e-05 | -10.91 | negative regulation of transporter activity | biological process | GO:0032410 | 96 | 48 | 18204 | 5365 |
MIR129-1,PRKCE,FKBP1B,SRI,CRHR1,CAV3,MIR33B,MIR448,GPR35,SUMO1,CTTNBP2NL,EPO,FKBP1A,CLIC2,KCNAB1,CAV1,MIR200C,PCSK9,MIR212,PPIF,MIR153-1,ATP1A2,PLN,MIR17,TLR9,MIR208A,GSTO1,NDFIP1,TCAF2,MIR1-1,MIR9-1,MMP9,MIR34A,MIR873,MIR34B,MIR133B,WWP2,MIR192,MIR24-1,MIR208B,CAB39,HECW1,OXSR1,DRD3,MIR30D,MIR186,MIR495,GSTM2 |
| 1.821e-05 | -10.91 | JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase) | protein interactions | 23210 | 198 | 83 | 19454 | 5460 |
CRMP1,PPIG,RBM27,HMGCS1,CARS1,NAA50,CDC16,STAC3,ELMO1,RANBP6,STAT1,SYT2,RBMX2,GTF2F1,UBE2I,RSRC1,MFAP1,TFIP11,NDUFA5,MED31,LUC7L3,H2BC11,ZCCHC17,CPSF4,ATG16L1,EEF1E1,NHP2,PSMC1,TRA2B,MED11,RNF5,GNA14,PPM1G,RPA3,SLU7,RBM23,DDX46,IRF3,NKAPD1,UCK1,CENPL,PPIL4,CSNK2A1,KARS1,MOV10,HMGA1,TAF7,VPS26A,ZCCHC10,ZNF24,DKC1,AKAP17A,CAND1,TMED9,TOP1,NKAP,RPLP1,BRD9,GATD3,CLK4,WDR6,SWAP70,CXCL14,RBPJ,APEH,NFKBIL1,RP9,UAP1,ARPC3,CAAP1,H1-3,TULP3,RPS7,MED9,DHX38,SSRP1,FLOT1,AHCYL1,H3C1,KRAS,HINT1,ZNF451,ARGLU1 |
| 1.821e-05 | -10.91 | YAF2 (YY1 associated factor 2) | protein interactions | 10138 | 198 | 83 | 19454 | 5460 |
PHC1,RAD23B,IFT57,CBX3,PCDH17,GABPB1,DDX39A,EEF1A1,H2AX,EEF2,RPS7,MAX,RPSA,PFDN1,PAX6,AHCYL1,PCGF6,ANP32B,NEDD8,TRIM26,PCGF3,HNRNPK,RING1,EWSR1,HSPD1,CDK12,DDX1,YWHAB,PPP1R11,AGR2,YWHAH,HNRNPA1,CSNK2A1,POLR3GL,API5,GAPDH,MDM2,HSP90AB1,CAND1,FZR1,ARF6,CLK4,RPLP0,E2F6,MXD1,KLF3,AGGF1,PPP1CB,HSPA5,SKP1,SRSF2,HMGB1,HSPA8,PGK1,PCGF2,YAF2,XRCC5,HSP90AA1,SMAD2,RIT1,COL1A2,YWHAZ,RPS17,FBXO7,ACO2,MAT2A,MYC,PAPOLA,GSTK1,CFAP20,UBB,MORC4,PPP5C,PDCD5,ZNF622,PRDX2,STAT1,RBBP4,CSNK2B,RPS20,PTEN,LORICRIN,UBE2S |
| 1.821e-05 | -10.91 | NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7) | protein interactions | 4701 | 198 | 83 | 19454 | 5460 |
TACO1,LMBR1L,CCDC90B,MRPS28,UBE2I,ATP5F1B,SNX3,UBE2L3,NDUFB10,NDUFB6,MTG2,NDUFAF2,COX6B1,NDUFB7,AUH,SUGP1,PMPCA,TOMM40,TUFM,RBM27,SAYSD1,NRP1,DNAJC19,TMX2,NGRN,RPS28,EXD2,NDUFC2,GFM1,NDUFS2,HSCB,SLC25A51,ARMCX2,STX7,PRKAB1,NDUFAB1,VAPB,PCLAF,NDUFA5,MTRES1,SSBP1,NDUFB4,SSMEM1,FUT1,GJA1,RFX5,NDUFA1,CYB5A,GATD3,NDUFS8,ATP5PD,COX14,GRSF1,MDFI,MTRF1,RAB5C,NDUFV2,RHOG,TMEM70,PPM1B,CHCHD1,MRPS26,NDUFB8,NDUFB5,HSPD1,NDUFA4,PQBP1,HINT2,ZC3H11A,DNAJC30,OLA1,FASTKD5,UBL4A,NDUFA2,MRPL11,AURKAIP1,METTL15,NDUFS3,NDUFS6,CRELD1,GFM2,NDUFA12,SLC25A24 |
| 1.821e-05 | -10.91 | VIPR1 (vasoactive intestinal peptide receptor 1) | protein interactions | 7433 | 198 | 83 | 19454 | 5460 |
SCAMP2,SFXN2,GPR89A,RETREG3,SLC30A7,SLC25A4,CD47,SC5D,ATP5F1B,SRC,ATP6AP2,TNPO3,VKORC1L1,TM9SF4,TMED5,RHOBTB3,ATP5F1A,ATP5MC1,REEP6,SLC35F2,TAPBP,ATP5IF1,VIP,RER1,CMTM6,SLC7A1,CYFIP2,CERS2,TMEM209,ZDHHC17,TIMMDC1,SYNGR2,FAM234A,COQ8B,HACD2,CFTR,KDELR2,SLC35E1,YIPF5,GHITM,STX17,SIGMAR1,FDFT1,TM9SF1,XPO5,RAP1B,MFSD5,DERL2,HNRNPL,SPPL3,ECHDC1,ARL6IP5,MSMO1,RAMP3,SLC25A17,TMEM97,ATP5MG,SEC61A2,SYNJ2BP,EI24,FAM241A,TMBIM6,XPO1,TMEM70,FAM241B,SLC20A1,PEX3,TMEM87A,RUSF1,WASL,CSE1L,SACM1L,RAB18,LPCAT3,PSEN1,ATP5PB,TMEM126A,YIPF3,NCSTN,KDELR1,SURF4,DHRS7B,GNAQ |
| 1.831e-05 | -10.91 | PHAX (phosphorylated adaptor for RNA export) | protein interactions | 51808 | 158 | 69 | 19454 | 5460 |
RPA3,DDX39B,EP300,NSFL1C,NUCKS1,G3BP2,PABPC5,RBMS2,CDC42,HSP90B1,ADNP,RPA2,LMNA,LUC7L3,EIF4B,RAN,REEP4,SNRNP40,SRPK2,RPL10,SNRPB2,GADD45G,CUL3,RPL7A,HNRNPC,CIAO1,NFYA,MYC,SNRPB,GEMIN8,RIT1,ELAVL2,MAP1B,RPS24,SRSF7,RUVBL2,EWSR1,KPNA2,THRAP3,KRAS,HUWE1,SSRP1,MEPCE,YTHDF2,RAF1,COMTD1,TULP3,SOX2,EEF1A1,SKA3,GEMIN7,PHB1,SRSF1,KRR1,COPS2,SNRPA1,CAND1,FZR1,STK3,NCBP2,RAB32,H2AC14,TRA2A,FAM20B,DDRGK1,XPO1,COPS5,SNRNP70,KPNA1 |
| 1.834e-05 | -10.91 | positive regulation of inflammatory response | biological process | GO:0050729 | 154 | 70 | 18204 | 5365 |
PDCD4,IL6,IL21,HYAL2,MIR126,CCL24,VAMP7,NUPR1,MIR142,NFKBIA,CAMK2N1,CD47,GPSM3,TNF,TLR3,CX3CL1,IDO1,IL12B,MIR144,KARS1,IFNG,CTSC,IL6ST,S100A8,CCR7,PIK3CG,PYCARD,TLR4,STAP1,NLRP1,FEM1A,IL18,CCL3,VAMP8,HTR2A,DDT,LDLR,DHX9,IL1B,CASP4,LTA,IL23A,CD28,DEFB114,FCGR1A,ALOX5AP,CASP12,NPY5R,NLRP6,TLR7,IL15,PDE2A,NMI,IFI35,IL2,CCR2,MIR21,PTGER4,FABP4,NINJ1,CD81,CNR1,TLR9,SETD4,MGST2,TLR2,NLRP3,MIR206,CCL1,OSM |
| 1.840e-05 | -10.90 | TMEM65 (transmembrane protein 65) | protein interactions | 157378 | 49 | 28 | 19454 | 5460 |
SFXN1,TMX2,JAGN1,CYBRD1,RTN4,PTGES,S100A10,SRPRB,FBXW7,TIMMDC1,TMEM101,ACAA2,NDUFS6,LMNA,ACAT1,HSD17B11,RETREG3,REEP4,MSMO1,ESR2,PARL,SLC7A8,FAM174A,SCN3B,TAX1BP3,CYB561,TM4SF18,PDZK1IP1 |
| 1.846e-05 | -10.90 | FYN (FYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 2534 | 414 | 155 | 19454 | 5460 |
PAK2,VAV2,RND2,BET1,SYK,CHRNA7,IL1B,HNRNPA0,CNTN1,EMC1,TMEM185A,HSPA8,DDX39B,KCNA3,HSP90AA1,CD226,RHOB,FAS,CCT2,GRB10,PRMT6,PIK3R3,GNB1,JAK2,RPL10,TOM1L1,SNRNP40,SIAH1,TAX1BP1,STAT1,TCAP,PRDX2,PTPRZ1,CD3G,SNRPD2,DLG4,CD79B,DOK4,TRMT6,SLC4A8,TMEM204,EEF2,MAK16,SOX2,ERRFI1,RAF1,FASLG,FLOT1,PRPS1,TNF,EPHA4,KIT,CDK5,PRPSAP1,CCT8,ABITRAM,SPHK2,CBL,TRAF6,DDX23,CTNNB1,HNRNPA1,PTPN5,PIK3R1,HMGA1,CCT7,HSP90AB1,PRKCQ,SRSF10,RHOH,CCAR2,TCP1,THY1,SH2D1A,KCNA2,HEXIM1,HSP90B1,JUP,CDK1,SDCBP,CDC42,MND1,CD2AP,SPR,HSPA5,PIK3R2,KDM1A,SIT1,CERS2,ANAPC16,GID8,RHOU,MAPRE1,SMAD2,CMA1,IVNS1ABP,TEX19,SKAP2,PRKACB,CNTNAP1,PTPN11,IL2RB,CSK,MAT2A,FGFR1OP2,SRC,TECR,YES1,PRKCE,TRIM27,TUBA1B,TMA7,ENO1,ACVR1,RP9,CTLA4,CD2BP2,WBP11,LBR,MAP1LC3B,CCT5,ATP5PB,SNRPG,ADD2,MEPCE,CTNND1,TRIM63,HNRNPK,NTRK2,ABCE1,SLC25A11,TSNAX,CD247,CNN3,NOS1AP,SHC1,MED21,SUV39H1,DAG1,GRAP,FCGR2A,HDAC6,GNG2,CD36,GRSF1,CAV1,CD2,LCP2,GRM1,RAC2,DLGAP4,AIP,ITK,HRAS,ACBD7 |
| 1.864e-05 | -10.89 | SSR4 (signal sequence receptor subunit 4) | protein interactions | 6748 | 201 | 84 | 19454 | 5460 |
TMEM106B,RPA3,MME,SOD1,BAP1,RNF113A,YAF2,RPL4,SSR3,ADRB2,NPM3,G3BP2,COIL,PGRMC1,TPT1,TOMM22,TIMM10,DET1,CFTR,GRM2,SSR1,VAPB,RPA2,SLC25A3,PIH1D1,CYB5R3,CCNF,LMBR1L,UQCRC2,PSPC1,PTEN,SEC61B,HECW1,ESR2,MAD2L2,RPL19,VIRMA,TECR,SMURF1,CUL3,RAB2A,MYC,OST4,KDSR,ATP5F1A,DCAF4,POMP,ILK,HSP90AA1,COP1,MAP1B,VDAC1,TRIM37,HUWE1,RIGI,MEPCE,PSEN1,RPSA,FAM13B,RAF1,UBL4A,CCDC47,DUSP1,RPN1,ILF2,RCHY1,COX4I1,PHB1,SSR2,SNRPD3,RPS16,CAND1,FZR1,HSP90AB1,CCT7,ELK1,EGLN3,TOMM70,ASB1,DDRGK1,HDAC6,COPS5,DRG1,RB1CC1 |
| 1.864e-05 | -10.89 | WDR36 (WD repeat domain 36) | protein interactions | 134430 | 201 | 84 | 19454 | 5460 |
FGF3,GNA11,RPL31,RPS24,G3BP1,KRAS,PTGES3,TP53,RAF1,TOP3B,SOX2,HDAC11,CHMP4C,EZH2,CBX3,RHOBTB1,NUPR1,GNAQ,CAPN2,KRR1,PWP2,ARL4D,NOB1,RPL35A,NOP58,FZR1,DHX15,SURF6,DKC1,FAM118B,IFI16,UTP6,DDRGK1,CHCHD1,MPHOSPH10,DDX23,MPHOSPH6,NLE1,SIRT7,PML,RPA3,SNAPC1,NUP50,EXOSC4,HSPA8,RPL4,STAU1,RP2,WDR3,NPM3,AATF,G3BP2,COIL,RPL27A,ELP3,APOBEC3C,RPA2,RPL26L1,UTP15,UBN1,ZNF330,EIF4A3,CCNF,PLCB2,FGFBP1,RPL13A,RPL35,SNRNP40,YES1,ESR2,SMURF1,CIAO1,MYC,RC3H2,ATG3,FBXW11,MECP2,RIT1,POLR1B,UBE2H,DNAJB6,EXOSC1,RPS5,ATP1A1 |
| 1.877e-05 | -10.88 | SNRPN (small nuclear ribonucleoprotein polypeptide N) | protein interactions | 6638 | 178 | 76 | 19454 | 5460 |
CRTAP,AGR2,SNRNP70,DDX23,RHOG,CRBN,TRA2A,SNRPA1,BUD31,SNRPD3,LSM5,RBM42,RCHY1,RAC2,ARL4D,EZH2,SNRPE,SART3,RND3,SF3B5,TP53,EXOSC8,CD2BP2,ESS2,KRAS,SNRNP48,LSM4,TSSC4,CDC40,SNRPG,MEPCE,CMTR2,LSM6,RHOB,GEMIN8,RC3H2,SFN,MYC,SNRPB,SKAP2,PRPF31,YES1,RHOJ,SNRNP40,SNRPB2,LRIF1,ZMAT5,SNRPD1,PRMT5,SF3B4,SNRPD2,LSM2,CTBP1,P3H1,PIH1D1,TFIP11,HEXIM1,NOL7,EIF4B,TXNL4A,WDR83,WDR77,SF3A1,MAFG,CFTR,CDC42,RND2,SNRNP27,GTF2I,LSM8,COIL,PRPF4,SNRPA,RAB5A,RNF113A,SF3B1 |
| 1.897e-05 | -10.87 | membrane microdomain | cellular component | GO:0098857 | 292 | 118 | 19108 | 5553 |
TLR1,CNR1,RANGRF,TRAF2,IL6ST,ADTRP,SLC2A1,FLOT1,ATP1A1,CDH13,ERLIN2,CD4,JAK2,OLR1,CD1A,CAVIN2,TLR2,ICAM1,PPT1,LAT2,SRC,SLC22A6,LAMTOR1,PLSCR1,TNF,SLC1A1,LCP2,HDAC6,ANGPT1,SLC6A3,BACE1,HTR2A,TGFBR2,VDAC1,EFHD2,DAG1,CAV2,ADCY2,STX12,CD14,RAP1B,ADD2,IKBKB,ATP2B4,EEIG1,DLG1,CHRNA7,CHP1,CD36,CTNNB1,BAALC,GJA1,STOML2,LAMP2,BCL10,FAS,GPM6B,CAV1,GPC1,SERPINH1,KCND2,PRNP,STOM,STIM1,SPRED1,CTSD,TFPI,CTNNA1,TUBB,ATP1A2,KCNA3,MLC1,RGMB,ABCG2,STOML3,S100A10,CD226,PSEN1,CBL,BST2,THY1,CAPN2,LYPD6,CAV3,EMP2,DPP4,SMPD2,CHRNB2,CLIP3,SLC6A4,TNFRSF1B,IGF1R,TNR,EFNB1,SLC1A2,KCNMA1,ADGRG1,HYAL2,BMPR2,ATP5F1A,TLR6,RAB5A,RIT2,NOS1AP,MME,EFNA5,BMPR1A,SDCBP,ERLIN1,PGK1,LRP6,RAP2B,BVES,ADRA1A,FURIN,FASLG,CORO1C,LDHB |
| 1.911e-05 | -10.87 | RAN (RAN, member RAS oncogene family) | protein interactions | 5901 | 405 | 152 | 19454 | 5460 |
EED,XPO5,NXT1,FOLR1,SIN3A,PSMB5,PHB1,SRSF10,PPIA,NUP35,DHX15,SUMO3,RANGRF,RPL7,SUMO2,XPO1,DDRGK1,GSTM3,MAGOH,SKIC8,IKBKB,AGR2,ZC3H7A,NEK9,PABPC1,HNRNPA2B1,SECISBP2L,RAD21,PAX6,SSRP1,KRAS,RBBP7,NUP42,ISG15,NUP153,SOX2,NUP37,SAP30,EEF2,TNPO2,RAF1,RANBP1,MTA2,SMARCB1,AP2S1,GLE1,EZH2,RAB4A,CHMP4C,AP2M1,RAN,GADD45G,MAD2L2,ESR2,RANBP6,FBXO22,RBBP4,BTF3,SMARCE1,CPSF2,MYC,CUL2,PSMA4,CUL3,PFDN4,ILK,SPCS3,CCT2,ATG3,BRCA1,LMNB1,HDAC5,HSPA8,NUP50,EP300,BMPR1A,PRKD3,SAP18,RANBP10,TRA2B,UFL1,ADRB2,STAU1,NUP62,H1-5,PIH1D1,NCBP2,CDK9,G6PD,FZR1,HDAC6,GAPDH,BMPR1B,GRSF1,DNAJC7,KPNA1,TSNAX,NXT2,SNIP1,NUP107,CSE1L,KPNA2,H2AX,EEF1A1,MAP1LC3B,SMAD1,KIF1C,TP53,PPME1,HBP1,BIRC5,NUPR1,TFCP2,EIF2S2,PHAX,MACROH2A1,UBE2I,CREB1,CCNF,OPTN,SF3B6,EIF4A3,VIRMA,NDN,PRKACB,H2BC9,AR,KPNA6,USP14,TUFM,SMARCA5,XPOT,CDC73,SMAD2,UBE2H,TRIM23,BAP1,INPPL1,RPA3,MBD3,HSPA5,MARS1,KDM1A,FBXW7,CFTR,SUMO1,CAPN1,UBE2M,RARS1,HEXIM1,LMNA,RPA2 |
| 1.916e-05 | -10.86 | ADCK1 (aarF domain containing kinase 1) | protein interactions | 57143 | 74 | 38 | 19454 | 5460 |
SLCO1B3,AIFM1,STUB1,CHRM4,ATP5PD,CHCHD3,PRELID1,CACYBP,APLNR,HSP90AB1,GNAI2,OPRL1,ADCK1,EXOC5,MOV10,HMGA1,CFAP20,GPR17,OPRM1,STOML2,HSP90AA1,TACR1,RUSF1,RAB1A,CXCR4,BCKDK,FKBP8,HNRNPDL,PTGES3,SLC31A1,CHCHD2,SLC15A1,GRPR,TGFBR2,HCST,NPY2R,MTCH2,ATP5PO |
| 1.916e-05 | -10.86 | PPIL3 (peptidylprolyl isomerase like 3) | protein interactions | 53938 | 74 | 38 | 19454 | 5460 |
ESR2,SNX3,TAGLN2,TMOD3,MTAP,WDR82,SNX12,IGBP1,CYRIB,SYNCRIP,MAPRE1,UBE2H,TNNC2,IL17F,GLOD4,AR,BAG3,CSNK2A1,PRSS12,MYC,AHCYL1,SEPHS1,RPS13,YTHDF1,PSMA1,SLU7,SOD1,RAD23B,PHC1,TAB2,GINS4,LMNA,CCS,DDX39A,SUMO1,E2F4,ATG16L1,FABP7 |
| 1.916e-05 | -10.86 | CDT1 (chromatin licensing and DNA replication factor 1) | protein interactions | 81620 | 74 | 38 | 19454 | 5460 |
PCNA,EP300,FAF1,TRIP4,MCM6,SKP1,DGCR8,FBXW7,KPNA2,TIMM13,TIMM8A,CCNA2,CKS1B,CDK4,TRAPPC13,HECTD1,CKS2,EZH2,CDK1,HDAC11,CCNF,FBXO31,CDC20,UBB,SLAIN2,CDC5L,FZR1,TOP1,COPS5,XPO1,GMNN,MCM4,BAZ1B,SMARCA5,CCNB1,DTL,CDC23,SPOP |
| 1.922e-05 | -10.86 | CMTM6 (CKLF like MARVEL transmembrane domain containing 6) | protein interactions | 54918 | 87 | 43 | 19454 | 5460 |
GPR173,SPINT2,SLC1A1,RETREG3,SYNGR1,CD274,COQ8A,S1PR4,DUSP10,TMEM237,B4GAT1,SNRPB2,APLNR,SUMO2,SPPL3,HM13,GPBAR1,GPR17,SLC35F2,LPAR2,PCNA,VIPR1,GLIPR1,TSPAN15,TCEA2,CD40,CLDND1,LPAR1,TNFSF8,SPG21,CDKN1A,TMEM106A,TP53,EHHADH,BPIFA2,COMTD1,MIEF1,SPTBN1,STK16,GPR35,SIGLECL1,TMEM95,P2RY12 |
| 1.938e-05 | -10.85 | DIMT1 (DIM1 rRNA methyltransferase and ribosome maturation factor) | protein interactions | 27292 | 181 | 77 | 19454 | 5460 |
COPE,RPL10,EIF3K,CCNF,RPS20,RPS12,AP2M1,BRCA1,H1-10,THTPA,UBE2H,AP2A1,RPS26,CUL3,RPL7A,MYC,BAG3,USP14,RPL26,STAU1,FBXW7,IRF7,UFL1,FTL,RPA3,DDX39B,BAP1,RFC4,GRM2,FGFR1,EIF2B3,RPA2,RPL7,EIF2B2,CAND1,RPS16,FZR1,ZBTB2,DKC1,RBM42,RPL8,SRP14,LDLR,SNRNP70,RPL24,RPL10A,RPL23,PDAP1,DRG1,DDX1,RPS2,CTNNB1,API5,DDRGK1,GPRASP2,HNRNPA1,THRAP3,HNRNPF,KRAS,RPS13,HNRNPA2B1,ABCF1,RPL31,TRIP4,DHX9,TRIM11,RPL3,RPL23A,RNF8,SRP72,RPS11,ILF2,RPL15,DDX39A,AURKAIP1,SOX2,MAP2K3 |
| 1.947e-05 | -10.85 | GRPEL1 (GrpE like 1, mitochondrial) | protein interactions | 80273 | 207 | 86 | 19454 | 5460 |
RIT1,DNAJB6,PFDN4,BRCA1,NIF3L1,TUFM,PMPCA,RAB11A,GRB10,AUH,MYC,MTG2,PARL,VIRMA,SMAD5,SUCLG2,GRPEL2,ELK3,CCDC90B,MTRES1,UBE2M,SCLT1,FKBP10,LMNA,RPRD1B,DNAJC27,CFTR,ELK4,STXBP1,DENND2D,BET1,GTF2H4,TOMM22,GRPEL1,EYA3,OXCT1,HSCB,NF2,RAB5A,GFM1,RAB9A,HSPA8,WBP2,RPA3,DNAJC3,HSPB1,DNAJC4,MRPS26,SHC1,RHOG,YWHAH,ATG7,DNAJB2,DPP4,MOV10,GRSF1,ELK1,RAB33A,GATD3,PHB1,RCHY1,AIFM1,SSBP1,ETV6,ACTR2,PDHA1,TPPP,SPG21,ELF1,MGARP,PPP2R1A,ISG15,RAF1,CMPK1,ANP32B,IMMP2L,CCAR1,DNAJC30,H3C1,KRAS,PSMA1,COX8A,HINT2,DNAJB4,HAPSTR1,SFXN1 |
| 1.952e-05 | -10.84 | chemokine activity | molecular function | GO:0008009 | 49 | 29 | 18094 | 5411 |
CXCL10,CXCL9,CCL24,CCL18,CCL3,CXCL3,CCL20,XCL1,CCL2,CCL4L1,CX3CL1,CCL27,CCL21,CKLF,CCL8,CXCL14,CXCL13,CCL11,CCL25,CCL23,CCL19,CXCL1,CXCL12,CCL1,CCL17,CXCL11,CCL28,CXCL8,CCL5 |
| 1.955e-05 | -10.84 | PHF3 (PHD finger protein 3) | protein interactions | 23469 | 103 | 49 | 19454 | 5460 |
HMGA1,NDC80,YWHAG,TMA16,HNRNPA1,YWHAH,DDX23,ANKRD50,YWHAB,UQCR11,RPL35A,PRNP,TOP1,SUMO2,EGLN3,H2AJ,RAF1,SUPT5H,CBX3,POLR2C,KRAS,H3C1,ASF1A,DPM2,SSRP1,MDC1,MYC,CUL3,SFN,ANAPC15,AR,SNRPB,YWHAZ,CCNF,TACO1,ZNF330,APEX1,VIRMA,ESR2,H1-5,UBA52,CCL3,RPA2,SNRPA,RPA3,PML,SIRT7,CLK1,STAU1 |
| 1.955e-05 | -10.84 | NEPRO (nucleolus and neural progenitor protein) | protein interactions | 25871 | 103 | 49 | 19454 | 5460 |
RPL3,RPL23A,RPS24,RPL31,RPL28,TFG,SCML1,POP5,SART3,MOB3C,RPL18,VPS33A,RPLP2,RPS16,GPRASP2,DDRGK1,WWP2,DDX23,RNF113A,PPM1G,NLE1,RPP14,WDR55,G3BP2,NPM3,RPL4,TIMM13,RPL27A,NOL7,RPLP0,RPA2,TMEM74,FGFBP1,PSPC1,RPS3,ZNF330,POP7,RPP25,ESR2,RPP25L,SNRNP40,ZNF668,MYC,LDHB,SP1,ATP1A1,RIT1,MECP2,DCAF4 |
| 1.955e-05 | -10.84 | LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2) | protein interactions | 28956 | 103 | 49 | 19454 | 5460 |
RING1,BLOC1S2,RRAGB,VRK1,FLOT1,LYPLA1,PRKAG1,PDHA1,NDUFS3,STX12,SDHB,RAC2,ATP6V1A,DPP4,SLC38A7,SLC38A9,RHOG,POR,TMEM184C,CDC23,PEBP1,RAB9A,TMEM185A,PIP4P1,SLC18B1,PRKAB1,RRAGA,UQCRC1,CDC42,BORCS6,FTH1,PTP4A2,BORCS5,MAP2K1,CSNK1G3,UQCRC2,VAMP3,MRPS21,RAB14,YES1,TXNDC12,LAMTOR3,BORCS7,ATP6AP2,ESR2,CDC16,RAB2A,BTF3,LAMTOR1 |
| 1.957e-05 | -10.84 | ZBTB10 (zinc finger and BTB domain containing 10) | protein interactions | 65986 | 147 | 65 | 19454 | 5460 |
HRAS,FUBP3,EGLN3,ZBTB2,CEP19,FAM98A,ZNF576,RPL35A,MIF,CSNK2A1,ERCC3,DDX1,FOXP1,RBM41,RTCB,S100B,LSM14A,PABPC1,PHF1,PAX6,UTP25,LSM4,G3BP1,H3C1,SOX2,FOXJ3,IPO8,RBPJ,MOB3C,RNF8,IRF8,CDC7,CSNK2B,RTRAF,PSPC1,CPSF1,ZNF330,ELK3,PPP1R10,CSTF3,VIRMA,ESR2,MAGOHB,RALA,NONO,AR,PPP1CC,MYC,PKP4,MORF4L1,CUL3,CHCHD4,TEX19,HIRA,COIL,G3BP2,FXR2,NF2,PPP1CB,GTF2H4,FUT8,EHHADH,LACC1,TOX4,RPA2 |
| 1.960e-05 | -10.84 | CSNK2A2 (casein kinase 2 alpha 2) | protein interactions | 1459 | 697 | 245 | 19454 | 5460 |
EP300,PCGF2,YAF2,HSPA8,FOS,RPS28,SAP18,FXR2,GPC4,TANK,RPL27A,CTBP1,SDC2,SF3B4,TAX1BP1,BTF3,CREBBP,MYC,MAF1,ZMPSTE24,CCT2,SREK1IP1,PICK1,RUVBL2,BCL7B,PRPS1,RPS4X,RUVBL1,HNRNPF,PTPN4,EEF2,TRAF2,SOX2,SUPT5H,TRMT1L,MTA2,WDR82,RBM5,SIN3A,HSP90AB1,LYAR,RPS10,YWHAG,XPO1,PPIB,YWHAH,IFT25,IFI16,AQP4,YWHAB,HSPB1,MGMT,RNF113A,ARHGEF6,RPL27,BAP1,HSPA5,KDM1A,HDAC3,GTF3C4,PPP1R8,ACACA,GIT2,PRKCA,HEXIM1,RPA2,CSNK2B,MRPS28,GCFC2,RPS3,ACP2,PPP1R1B,SMURF1,MTPN,UBE2H,UBE2E3,EIF3G,EIF1AD,PIWIL2,MEPCE,ESS2,KIF1C,TP53,RPSA,SNAP29,NUPR1,PHC1,RAD1,RP9,EEF1B2,SSBP1,STT3A,CDC5L,SURF6,NKAP,RPS16,CSNK2A1,PPIL4,SNRNP70,HADHA,DCTN3,CFDP1,SAT1,ATP5IF1,NKAPD1,SKP1,AZGP1,RGS19,COIL,NOP53,NDE1,WDR77,ADNP,MED23,POLR2F,RPS9,POLR3B,CDC7,RSRC1,EIF3K,VPS72,ERH,LGALS3,TUBB,RBBP4,RPL7L1,ATF1,RIOK2,CUL3,RPS5,HSP90AA1,YWHAZ,PPAN,TRIP4,HSPD1,PCGF6,SSRP1,GTF3C3,AP1M1,GNL1,G3BP1,PCGF3,RBBP7,ZNF592,SAP30,TULP3,MAK16,RBM12,RAF1,SART3,COPS2,RPLP1,GPR137,RPL8,EGLN3,EIF3D,FGF1,DPY30,PRPF19,HMGA1,CAMSAP2,RPL23,MED4,STX1A,WDR12,SKIC8,SQSTM1,CCDC106,SIRT7,PRPF4,DVL2,RPA3,PPM1G,CRYZ,MBD3,NUCKS1,FBXW7,HMGB1,PPP1R2,EIF3J,ATG16L1,SAP30BP,SF3A1,PAX9,ZCCHC17,HSP90B1,LMNA,RPS12,PTEN,RPS20,HEXIM2,GTF2A1,PELP1,OPTN,CCNF,RPL22,DEK,VIRMA,PYCR2,ZNF687,CSK,CAP2,NRP1,CCHCR1,NCKIPSD,ZNHIT3,PIP4K2C,ASCC1,HAPSTR1,RING1,TCOF1,TFPT,EIF3E,THRAP3,DNAAF10,HUWE1,ZSCAN5A,ANAPC11,TAF1D,MAP1LC3B,CCT5,JPH4,TBK1,TMEM126A,RAD23B,RB1,RPL12,PTPN1,MRPS23,NOP9,CAV1,AKAP17A,MDM2,EIF2B2,PRNP,EIF2B5,TOP1,KLF1,HDAC6,ADH1A,BRD3,OSBPL8,PSMD7,MED21,SPP1 |
| 1.962e-05 | -10.84 | NFATC3 (nuclear factor of activated T cells 3) | protein interactions | 4775 | 42 | 25 | 19454 | 5460 |
FOS,FLOT1,PIP4P1,RP2,PSMA5,PPP3R2,SUFU,CSNK1A1,RBPJ,TRAPPC3,CDK6,ENO1,SSBP1,ESR2,VIRMA,APEX1,EGLN3,YWHAH,YWHAG,CUL3,SFN,MOV10,YWHAB,BICD2,YWHAZ |
| 1.962e-05 | -10.84 | LAMTOR4 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 4) | protein interactions | 389541 | 42 | 25 | 19454 | 5460 |
SLC38A7,LAMTOR2,MYC,KXD1,NONO,SLC38A9,ARL6IP6,LAMTOR1,CDCA3,LDLR,LAMTOR3,BORCS7,ESR2,RRAGA,BORCS6,DUSP22,TUBA1A,SNAPIN,BORCS5,BIRC5,CCR1,FLCN,RING1,BLOC1S2,RRAGB |
| 1.967e-05 | -10.84 | HTRA2 (HtrA serine peptidase 2) | protein interactions | 27429 | 254 | 102 | 19454 | 5460 |
CUTA,CUL3,PYCR1,HTRA2,MDH1,KBTBD6,NDUFAF4,CHCHD3,TUBB,TAMM41,MRPL23,TIMM13,MTX2,MFAP1,VPS18,BIRC2,NMRAL1,EXD2,CD40,NT5C3A,RANBP10,NDUFS2,NDUFV2,MRPS35,ARMC8,HAX1,MRPS26,TRAF6,MRPL18,AK2,PHB1,POLR2L,NDUFS8,CCAR2,NUP37,TRAF2,TUBA1A,POLR2C,NDUFA12,NDUFS6,PNMA2,PIR,BAG2,MRPS11,RPAP3,MKLN1,CDK5,MAEA,USP30,TNF,NTAQ1,TIA1,PYCR2,UBE2H,PEA15,OAT,CHCHD6,CSNK2B,TRAF1,SNRNP27,POLR1D,MYL12B,SAMM50,VPS4B,CDK1,PAK5,COX6C,MAVS,GID8,BNIP3L,POLDIP2,TMEM209,MRPL41,COX5A,AREL1,MUL1,BCL10,LDLR,DSTN,COX4I1,ARMC1,AIFM1,SLC25A12,MRPL24,TOMM70,RPL35A,ZMYM4,MTARC2,EEF1A1,MRPL47,NDUFA2,CENPM,STRBP,TBK1,SOD2,PPP4C,NDUFS3,HSD17B10,CLPB,VPS16,ABHD10,REXO2 |
| 1.969e-05 | -10.84 | DNAJC28 (DnaJ heat shock protein family (Hsp40) member C28) | protein interactions | 54943 | 95 | 46 | 19454 | 5460 |
MRPS18B,HECTD3,ATP5PF,MRPL22,ATP5F1D,NDUFA2,ATP5PB,RPL18,NDUFA12,NDUFS6,NDUFS3,PHB1,COX4I1,MRPS9,MRPS23,ATP5PD,NDUFS8,MRPL50,NDUFV2,RPL6,MRPS35,STOML2,GRSF1,MTRF1,MRPS26,DCAF5,DLAT,MRPS7,RPL4,PHB2,MRPL40,NDUFS2,NDUFAF3,NDUFA5,MRPS34,ATP5PO,MRPL13,PTPMT1,DLST,TACO1,NDUFAF4,ATP5F1B,PYCARD,PYCR2,RPL7A,NDUFAF2 |
| 1.969e-05 | -10.84 | CDC42BPB (CDC42 binding protein kinase beta) | protein interactions | 9578 | 95 | 46 | 19454 | 5460 |
BRIX1,SLC31A1,STK38,FBXW7,GRPR,STAU1,RHOU,RPA3,RPA2,CDC42,RND2,PPP5C,ESR2,VIRMA,PYGM,RHOJ,TAX1BP1,CSNK2B,LURAP1,SP1,RHOB,H2BC9,DNAJC5,CDKN3,CUL3,PTGES3,FLOT1,KRAS,KCTD17,RPL3,SIKE1,RND3,UBXN2B,LGR4,TOP3B,RAF1,TTC9C,TRIM35,HNRNPL,RHOH,GJA1,RAC2,RAB35,RHOG,HDAC6,DPP4 |
| 1.987e-05 | -10.83 | ANXA5 (annexin A5) | protein interactions | 308 | 210 | 87 | 19454 | 5460 |
EMC2,ANP32B,ABHD10,TRIM26,KRAS,HUWE1,HSPE1,TRIM37,SOX2,CCS,H2AX,ISG15,ANP32A,RAF1,ITGB5,RNF8,EZH2,PIK3CA,TFCP2,PLS3,EED,UBE2N,CGAS,SUMO2,MIF,HDAC6,PPIB,XPO1,HNRNPA1,ACP6,ZNF207,CALR,PDIA3,PGAM1,ARMC8,FGR,GSTO1,AGR2,TXNL1,ATP5IF1,PGK1,NMRAL1,OR1M1,RPA3,SOD1,PRKD3,DDX39B,BAP1,PEBP1,BCL6,EMC1,EIF5B,NEK7,CFTR,MRPL12,CDK7,SUPT4H1,AKR7A2,PCK2,SF3A1,GSTP1,FDFT1,RPA2,RPRD1B,IDH2,HSP90B1,METTL14,TRIM24,IRF2,CCNF,SUCLG2,SNRPB2,TENT5C,TUBB,ACTB,HMGCS1,GMPS,DNAJC8,BAG3,MYC,PMPCA,GFUS,UBE2H,SPOP,FAS,LGALS8,BRCA1 |
| 1.995e-05 | -10.82 | mRNA metabolic process | biological process | GO:0016071 | 608 | 226 | 18204 | 5365 |
RPRD1A,SNRPE,SMU1,HNRNPC,SNRPA1,PRPF19,PELO,DHX15,CDC5L,COIL,NR1H2,TAF11,DDX39A,RBM23,SF3B5,CNOT6,LSM8,HNRNPAB,PYM1,ZCCHC7,CDK12,CWC15,CWF19L1,SART3,CPEB1,EXOSC4,HNRNPA0,TMT1A,CPSF4,LSM2,RPRD1B,SMNDC1,SUGP1,VDR,ZMAT2,SKIC8,WDR77,CSTF3,MAGOH,SNRPD3,CNOT2,WTAP,DKC1,GEMIN8,SRPK2,SRSF7,EXOSC8,SF3A1,PRMT5,THOC3,LSM4,DHX9,AKAP17A,CLP1,DBR1,ELAVL4,DXO,SRSF10,RC3H2,SNRNP48,SMG5,RBFOX2,KHDC4,PAPOLA,FASTKD5,RAMAC,ARB2A,ECD,RBFOX3,CDC73,RNF113A,WBP11,SNRNP70,SNRPG,DHX16,LSM10,SNRPA,TIA1,BUD31,ALKBH5,TAF2,SMG8,SYNCRIP,ZCRB1,ESS2,RBM22,DDX39B,AGO1,SCNM1,LSM5,VIRMA,SLU7,CREB1,ARMC7,DDX1,SNRPB2,HNRNPA1,RNASEL,DDX42,THOC2,SREK1IP1,THOC6,THRAP3,SMN1,TENT4A,SRSF12,TSSC4,LUC7L3,SF3B4,SNIP1,IK,RSRC1,CD2BP2,PABPC1,TRA2B,PRPF18,RBM5,SNRPD2,HNRNPF,KIN,RBM42,MRTO4,GCFC2,LSM3,FRA10AC1,TSEN34,TFCP2,TRMT6,MFAP1,AKAP8L,PPIH,CASC3,TXNL4A,PRPF31,RBM38,SNRPD1,CEBPG,H2AB1,DIS3L,NUDT12,CNOT6L,ETF1,PDE12,PNRC1,EIF4A3,SNRPN,TAF9,SF3B1,RBM17,SRSF8,SRSF2,CMTR1,PRPF4,CCAR2,S100A10,HNRNPH3,SNRNP27,WDR83,HNRNPL,SSU72,UPF3B,EXOSC3,CELF6,SRSF4,EDC3,ZNF326,YTHDF2,CNOT7,EIF3E,NUDT16,UBL5,LSM6,LGALS3,METTL14,TRUB1,CDC40,PPARG,TFIP11,RBM15B,TRMT61A,CPSF2,CTNNBL1,DDX46,PQBP1,DCP2,PPWD1,TRA2A,SNRNP40,ALYREF,DHX38,MAGOHB,NCBP2,DDX5,ZMAT5,THOC1,RBM27,TP53,TAF10,TAF7,DDX23,ZRANB2,TENT2,USP39,TSEN54,HNRNPK,SF3B6,POLR2G,ATF4,SNRPB,NONO,HNRNPA2B1,RBM41,NOVA1,RBMX2,SMG9,CBLL1,HSPA8,PPIL3,SAP18,NRDE2,ZNF473,CNOT8,CMTR2,CSTF2T,SRSF1,GEMIN7 |
| 1.998e-05 | -10.82 | CLCC1 (chloride channel CLIC like 1) | protein interactions | 23155 | 184 | 78 | 19454 | 5460 |
HAX1,TMEM30A,STYK1,RHOG,ESYT1,LAMP3,TMA16,TMBIM6,ATG9A,LAMP2,DPP4,RAB5C,MARCHF5,SLC25A46,LMAN1,TMPO,STX6,DNAJC1,HNRNPL,ARF6,GJA1,HSD17B11,RAC2,PTPN1,RAB35,PLD3,SEMA7A,FURIN,STIM1,RPN1,RAB4A,PTRH2,DNAJC25,COMTD1,CCDC47,FKBP8,RIGI,PSMA5,KRAS,RAB3B,VDAC1,DNAJC30,IGF1R,CYP2C9,PLSCR1,TMT1A,NTRK3,FIS1,RIT1,CALU,CUL3,TBCE,RAB11A,CIAO1,SEC63,SPCS1,RMDN3,PTEN,SEC61B,LMBR1L,ACACA,SSR1,FGFR1,OTULINL,RND2,CDC42,SEC62,ST7,PXMP2,STX7,DNAJC22,NF2,SYVN1,RAB5A,RAB9A,DERL1,DNAJC3,TSPAN15 |
| 2.004e-05 | -10.82 | SLC30A8 (solute carrier family 30 member 8) | protein interactions | 169026 | 69 | 36 | 19454 | 5460 |
GPR37L1,TMEM50A,SFT2D2,ORMDL1,RUSF1,DERL1,PCNA,SYS1,RELL2,GRM2,TMEM31,VAMP2,LMNA,TMEM14B,CMTM7,SELENOK,ERVFRD-1,VAMP1,YIPF4,OTULINL,REEP4,TMEM237,CD99L2,ELOVL4,HSD17B11,SYT2,RMDN3,CGRRF1,FCER1G,TMEM11,REEP6,FAXDC2,PLN,TMEM208,SCN3B,HMOX2 |
| 2.004e-05 | -10.82 | MARCHF1 (membrane associated ring-CH-type finger 1) | protein interactions | 55016 | 69 | 36 | 19454 | 5460 |
JAK1,MAVS,BMPR1A,LRP10,EXD2,FKBP8,GOSR1,USP8,TGFBR2,PPP2R1A,OTULINL,LGR4,IFNGR1,STXBP1,ADIPOR1,MTCH2,NOTCH2,MET,CSNK1G3,TFRC,ABCB1,BMPR2,SLC12A2,HDAC11,STX10,ADGRL3,CD86,STX6,HNRNPL,SNX3,NDFIP1,SLC25A46,MARCHF5,REEP6,UBE2H,UBE2D1 |
| 2.012e-05 | -10.81 | KLF8 (KLF transcription factor 8) | protein interactions | 11279 | 326 | 126 | 19454 | 5460 |
LBR,ZMYM4,ZMYM3,YTHDF2,ILF2,PSMC3,TAF2,DMAP1,RBM34,RING1,MRPS18B,RPS13,EIF3E,PSMA5,NOC4L,AKAP8L,TAF9,FOXP1,PSMD7,MYBL2,PSMB1,GATAD1,TFE3,AIFM1,COX4I1,BRMS1L,PSMC4,RPL26L1,E2F6,HNRNPH3,MRPS34,BAP1,ZKSCAN1,RPS15,DGCR8,GTF2I,HMGB1,RPS17,TAF5L,PSMB2,SEC13,CALU,EIF3G,TADA3,QSER1,PSMC5,ING2,GANAB,TRIM24,PSMA6,MID1IP1,PDCD5,ADRM1,GABPA,PPP2R1A,ELF1,BUD23,MAX,RPS11,PCNA,RUVBL2,FHL3,LSM14A,PSMD12,PCGF6,RAD21,FOXP4,PSMA1,ZNF609,G3BP1,PSMA2,ZBTB14,VDAC1,XPO1,NOL4,EIF3D,CLPX,PSMD3,BAZ1B,ZHX1,PSMB5,PHB1,PSMB4,MEAF6,RPS10,HNRNPL,CCAR2,SUMO2,PRDX3,PGRMC1,PSMB3,TRMT112,ATP5PO,CTBP1,PSMB7,ADNP,PSMA3,EP300,PSMC1,MRPS7,G3BP2,PHB2,NOP53,STAU1,PSMD1,KANSL3,RPL39,RPS29,COX6B1,CREBBP,PSMA4,NOP16,RPS5,SP1,NSA2,PSMD14,ZMYM2,RPL37A,PHF21A,VDAC2,PHF12,VPS72,PSMB6,PRRC2A,PSMD4,PSMD6 |
| 2.022e-05 | -10.81 | RNA Polymerase II Transcription | REACTOME pathways | R-HSA-73857 | 159 | 75 | 10285 | 3229 |
TCEA1,POLR2L,POLR2D,SNRPG,GTF2H2,SNRPB,GTF2F2,GTF2A2,FYTTD1,SUPT4H1,POLR2G,ELOC,TAF10,TAF7,POLR2F,POLR2B,TAF2,MIR939,MNAT1,CDK7,GTF2E2,UPF3B,CPSF4,CSTF2T,MIR1234,THOC1,MAGOH,SRSF4,CCNH,ZC3H11A,GTF2A1,MIR636,CASC3,CDC40,SRSF1,GTF2H5,TAF9,SNRPE,CPSF1,PAPOLA,NCBP2,SNRPD3,EAF2,DDX39B,SUPT5H,POLDIP3,CSTF3,THOC3,SLU7,THOC2,GTF2E1,CHTOP,MAGOHB,CDC73,POLR2I,THOC6,LSM10,GTF2F1,ZNF473,SKIC8,CLP1,GTF2H4,CPSF2,POLR2C,SSRP1,SRSF2,SRSF7,ERCC3,DHX38,TAF11,GTF2B,ALYREF,CDK9,EIF4A3,DDX39A |
| 2.033e-05 | -10.80 | TSC1 (TSC complex subunit 1) | protein interactions | 7248 | 272 | 108 | 19454 | 5460 |
IKBKB,RHOG,CDKN1B,YWHAB,LAMP2,HR,RAB5C,SELENOW,YWHAH,SHC3,YWHAG,CTNNB1,RHOH,CNTROB,HSP90AB1,HOMER3,EZH2,RAB4A,PPFIA2,HGS,CHCHD2,KRAS,RUVBL1,ENKD1,RPAP3,RUVBL2,PICK1,SLC39A7,SLC39A3,GCC1,LAMTOR1,YWHAZ,ICA1,LMO2,TMED5,MYC,CUL3,RAB11A,PRMT6,RHEB,BAG3,HECW1,FBXO22,B4GALT3,ESR2,ARF1,FRS3,PIH1D1,RRAGA,HSH2D,BEND5,TANK,RALYL,NPTN,MYOZ3,NRBF2,STX7,RAB5A,TRAPPC2L,BECN1,SMG9,MOV10,EDEM1,LAMP3,PPP1R18,TOP1,CNIH1,STX6,CDK6,NEFL,TRAPPC13,DOK5,MTCH2,KIF1C,CDK4,SERTAD1,DNAAF10,RIGI,IGF1R,GEMIN8,IGF2BP1,CASC3,ANKIB1,AKT1,RAB2A,CCNB1,CIAO1,CCL28,DAPK1,DYRK1A,LURAP1,B4GALT1,MSN,CDK1,CDR2,TFIP11,TMOD1,MYLIP,ATG16L1,FTH1,NF2,KDM1A,FBXW7,RPA3,TRIM3,FAM222B,DERL1,RAB9A |
| 2.033e-05 | -10.80 | RDX (radixin) | protein interactions | 5962 | 272 | 108 | 19454 | 5460 |
ICAM2,ATG7,CDK5RAP3,FABP5,PSMB5,CORO1C,TRAPPC10,OCRL,TCP1,SPTAN1,SNX2,SLMAP,CCT7,RAF1,ACTN4,MAPK10,PPP2R1A,EEF2,PLS3,GDI2,UCKL1,SH2D5,RINT1,HNRNPA2B1,CCT8,MYO1B,HNRNPF,LASP1,TRIM37,PSMD12,IMPA2,TXNRD2,HNRNPC,UFD1,BRCA1,NTRK3,TRMT6,FAM83B,TAGLN2,ATP5F1B,ACTB,ESR2,ATP6V1C1,NOTCH2,PPP1CB,MRPL12,ACAA2,EIF4B,SPECC1L,NUP50,DDX5,UCHL3,STAU1,CMAS,CALR,ISYNA1,AIFM1,AKR1B1,TES,RAC2,CPNE1,SLAIN2,G6PD,TP53,CCT5,MAP1LC3B,NHERF1,NUPR1,PALM2AKAP2,SNIP1,PPP1R12A,CPNE2,SNAP23,HSD17B10,HSPE1,L1CAM,CAPZA1,CSK,DEPDC1B,TUFM,PHKA1,CALU,CCNF,ENO1,CTTN,GTF2A1,MSN,ZNF622,ROCK1,VIRMA,ARHGAP1,CAPN1,CFTR,RPA2,DRD3,FGFR1,SLC12A2,RPA3,DVL2,BAP1,PML,RNF113A,LCP1,PRDX6,GTF2I,NF2,PIAS1,ABCC2 |
| 2.050e-05 | -10.80 | RAP1GDS1 (Rap1 GTPase-GDP dissociation stimulator 1) | protein interactions | 5910 | 136 | 61 | 19454 | 5460 |
ZNF451,NAE1,KRAS,OLA1,RAP1A,ETFB,DIRAS1,RAB6B,STIM1,GNAZ,IFT22,POLR2L,HRAS,RAB31,RAC2,RAP1B,TTC9C,RAB1B,RBM42,NKIRAS2,DIRAS3,FAM20C,DIRAS2,MOV10,GAPDH,RAP2B,COPS5,RHOG,DNAL1,VASH1,SEPTIN6,RLIM,RAP2A,HSPA8,PAFAH1B2,PPP1R2,SNX24,HSPA5,UNC45A,GINS3,CAPN1,RASL12,RABL3,CDC42,CNPY3,OTULINL,LMNA,RASL10A,RAB28,CTNNA1,MSN,RRAS2,TENT5C,GMDS,PPP5C,CSK,AKT1,RALB,USP14,RHOB,RAP2C |
| 2.051e-05 | -10.79 | AURKAIP1 (aurora kinase A interacting protein 1) | protein interactions | 54998 | 281 | 111 | 19454 | 5460 |
NDUFA12,NDUFS6,RAF1,TRMT1L,ETFB,MRPS17,GTF3C3,KGD4,ETFA,HINT2,FBXO11,FHL3,MRPS11,HSPD1,PPAN,MRPS26,AGR2,MRPL9,NDUFV2,DDX50,CLPX,MRPS35,NDUFS8,LYAR,MAGED2,RPL8,NDUFA5,ATP5PO,MRPS18A,TIMM13,PRDX3,MRPL12,MRPS7,NDUFS2,STAU1,NOP53,DCTN3,HADHA,MRPS25,FTSJ3,CHTOP,NOA1,MYC,PYCR1,CUL3,NOP16,NDUFAF4,ATP5F1B,MRPL23,RPL7L1,MRPL13,TACO1,DLST,GEMIN7,ABHD4,SRP72,LLPH,NDUFS3,RBM34,AURKAIP1,FNTB,STRBP,ATP5PB,NDUFA2,MRPL47,MRPL11,MRPS18C,MRPL22,MRPS33,SEPTIN7,MRPS18B,RPL3,HSD17B10,NKRF,CSNK2A1,KARS1,ATP5PD,MRPS23,MRPL24,MRPL50,MRPS9,TIMM8B,STT3A,SSBP1,RPL32,KRR1,RPL26L1,MRPS34,MMADHC,MRPL10,WDR83,RPS14,POLDIP2,DNLZ,MRPL17,NME4,MRPL41,MRPL40,RNF113A,DLAT,MRPS16,PYCR2,TECR,MRPS21,RPL13A,MRPS28,GSK3A,PRKRA,EIF2S2,ACAT1,MRPL53 |
| 2.053e-05 | -10.79 | KDM4A (lysine demethylase 4A) | protein interactions | 9682 | 59 | 32 | 19454 | 5460 |
TOP3B,MYL12B,TP53,PRDX3,SPRR1B,ABHD5,CCL19,RNF8,POC1B,TRA2B,H3C1,HDAC3,KDM4B,FBXL4,CAPZA1,POLDIP3,RSPH1,MOV10,AR,STK4,CSTA,CHTOP,STK11,H2AZ1,TUBA1B,SRSF1,SNRPD2,PRMT5,LDLR,RB1,FBXO22,VIRMA |
| 2.053e-05 | -10.79 | SERP2 (stress associated endoplasmic reticulum protein family member 2) | protein interactions | 387923 | 59 | 32 | 19454 | 5460 |
TM4SF18,CYB561,CKB,TMEM106C,TMEM179B,SLC38A1,STX1A,MFSD14B,SLC38A7,SCN3B,OPRM1,TM4SF19,FCGR2A,FNDC9,TMEM237,RNASEK,ELOVL4,ACTA2,RETREG3,STOM,LMNA,TMEM31,TMEM14B,TIMMDC1,DDX39A,PSEN1,TMX2,PTGES,CYBRD1,EWSR1,GNG5,BSCL2 |
| 2.058e-05 | -10.79 | MTPN (myotrophin) | protein interactions | 136319 | 150 | 66 | 19454 | 5460 |
GUK1,MPST,RIGI,RAB1A,THNSL1,HINT1,EZH2,MINDY3,DNAJC2,CAPZA2,GNB1L,MSRB3,HADH,GLRX5,DSTYK,MSX2,CNTROB,TMEM237,NUP35,HDHD3,COX4I1,MTAP,ATP6V1A,GATD3,AK2,LANCL2,AGR2,SHC1,DNAJC4,NFKB1,PDIA3,DPY30,CSNK2A1,LRRC40,OXCT1,CRYZ,G3BP2,CMAS,SOD1,BOLA3,RPS28,CSTB,HMCES,PMAIP1,PRDX6,GSTP1,PIH1D1,LAP3,SPR,UBLCP1,TXN,TXNDC12,RBBP4,CLIC4,EFHD2,CYRIB,TRIM24,PIP4K2C,UBE2H,FXN,MDH1,PNPO,PMPCA,PTPN11,GMPS,ISCA2 |
| 2.059e-05 | -10.79 | positive regulation of cell population proliferation | biological process | GO:0008284 | 992 | 351 | 18204 | 5365 |
PLAC8,CXCL12,BCL6,FGF7,BCL7B,HMGB1,CD1D,MIR495,PYCARD,MIR23A,HRAS,ZNF304,AGER,MZB1,SLC39A10,CX3CL1,PTGFR,RBPJ,IL10,XCL1,ACTB,DDRGK1,FGF3,CCR3,LBH,FGF17,TNF,RPS3,PHB1,NMBR,CX3CR1,PRKCA,GJA1,MIR214,MIR17,BCL7C,PDCD1LG2,MIR657,CAPN1,CCR2,F2,SLC25A27,AIF1,SPHK2,CDKN1A,CXCL10,VIPR1,NPY5R,SLC25A5,MIR301A,CITED1,ILK,FGF22,CNOT8,TSHR,FGFR1,ITGAV,ATXN1L,RAC2,CDK6,APLNR,TLR4,CCL11,MIR590,CIAO1,ST6GAL1,ACTL6B,SDCBP,MDM2,SSR1,IL13,IL21,CLEC7A,MAP3K3,RNF187,PRKCQ,MIR711,RHOG,IRAK4,TSPO,S100A6,CDKN1B,CCNA2,EPCAM,RPL23,SP1,UFL1,JAML,MIR503,IL34,EGR1,CNOT7,MNAT1,EPO,S100B,LHX2,IL7,CHRNB2,IL3,EZH2,CHRNA7,DHX9,PROX1,GREM1,SEMA5A,FOLR2,CDH13,IL1A,TGFB2,SRPK2,KRAS,NOTCH2,CD209,ADAMTS1,NCK1,RPRD1B,FGF10,FZD3,PDF,SOX9,PROK1,CSNK2A1,MIR20A,GHRL,DLG1,CNOT6,MVD,SLC35F6,EFNB1,CAV2,KDM1A,IL5,CDCA7L,REG1A,FOSL2,LTA,SHC1,PPP1CC,SCG2,IL12A,MIR132,HTR2A,CNTFR,OSR2,CDK1,APLN,SASH3,MIF,IL6ST,CSF2,MAB21L1,HEY2,EPHA4,CCL5,CDC42,FZR1,PRDX3,FERMT2,MYC,SFRP1,IGF1R,MIR126,MYD88,TACR1,IL4,MIR208A,PTN,HBEGF,CD81,MIR146A,FXN,CD46,CLDN1,FAM98A,GPBAR1,HTR1A,MEF2C,CAV3,ODC1,RPS9,CD28,DERL2,CD40,FGF16,HILPDA,ATF3,NME2,NKX3-1,HDAC6,NOG,MIR101-1,EGFL7,SERTAD1,SELENOK,LACRT,CNOT6L,TFRC,GPAM,WNT2,NLGN2,MARCKSL1,TRAF6,AGGF1,MIR222,CD38,STAT5A,CDK4,VIP,DPP4,PTHLH,CCL19,PML,IL2RA,DISC1,HCLS1,TERT,MIR141,SRC,TNFSF12,NME1,IL18,REG1B,LEP,FASLG,CD40LG,IFNG,BIRC5,ARHGAP5,TIAM1,PIK3CA,CD47,CAMP,MIR135B,CACUL1,OSM,PIK3R1,NR2E1,CUL3,CCNB1,NDUFAF4,NTRK3,NTRK2,FGF23,BMPR1A,MECP2,COX17,AKR1C2,IL15,TICAM1,MIR29A,TIMP1,CCAR1,ADGRG1,IL23A,VEGFA,CD248,AKT1,TGFB3,IL1B,WNT7A,PPP3CA,VSTM2A,CDC7,SMAD4,ITGA2,RPS4X,WDR77,CALR,ROMO1,HMX2,IGF1,BRD9,PDCD10,CCL24,TOX,CTNNB1,TNFAIP3,GID8,PID1,GNAI2,KIT,XBP1,TNFSF13,MIR320A,ODAM,AR,CRKL,SS18,CCND1,MIRLET7B,TGFBR2,IL2,MIR130A,MIR221,STAT1,FGF1,BST2,B4GALT1,TIRAP,NRP1,BCL2L1,JAK2,PTEN,BAD,ROGDI,MIR448,MIR10B,GLCE,ACER3,CD274,FOXP3,AKT3,DHPS,ACTL6A,PRL,JUN,PNP,GNG5,EMC10,PELI1,GPR37L1,VEGFC,MIR10A,MTA3,IL12B,SLC7A1,FOXP1,POLD4,ASPM,CD86,MMP9,STAMBP,ID4,IL6,HAPLN2,SMARCD3,TLR9,MIR548C,RTN4,EMP2,FGFBP1,MIR21,MIR30B,MIR519D,SELENON,AQP11,MIR204,WNT10B,SSBP3,PAX6,CD80 |
| 2.060e-05 | -10.79 | Regulation of RAS by GAPs | REACTOME pathways | R-HSA-5658442 | 70 | 39 | 10285 | 3229 |
PSMD12,PSMC4,CUL3,PSMC1,PSMB5,PSMA3,PSMB1,PSMD3,PSMB7,PSMB3,PSMA6,PSMB2,PSMD1,PSMA2,PSMB6,PSMB11,PSMC5,PSMB10,PSMA5,HRAS,PSMA4,PSMD7,PSMB9,SPRED2,SEM1,PSMD6,PSME1,PSMB4,PSME2,PSMD10,PSMD4,UBB,SPRED1,UBA52,RPS27A,KRAS,PSMA1,PSMC3,PSMD14 |
| 2.067e-05 | -10.79 | ORF3b (ORF3b protein) | protein interactions | 1489670 | 114 | 53 | 19454 | 5460 |
BAG3,MLF2,RUNX1,TBCE,NAPA,EPHA2,BLVRA,ALB,PSMC5,LRP12,STUB1,MYRF,TOM1L1,NDFIP1,PSMD4,MAFG,IL6ST,SLC4A10,UBL3,PSMC4,MET,FGFR1,WBP2,LRP10,BMPR1A,DDX39B,USP8,GLO1,WWP2,DICER1,NOVA1,SNX17,MYEF2,PCDH9,KIAA0232,STX6,MDM2,CCAR2,IFNGR1,ACO1,TP53,BMPR2,ACVR1,TRAFD1,HINT1,BAG2,JAK1,LTBR,DDR1,PSMD12,ACVR1B,TGFBR2,HUWE1 |
| 2.072e-05 | -10.78 | ARHGDIA (Rho GDP dissociation inhibitor alpha) | protein interactions | 396 | 167 | 72 | 19454 | 5460 |
IMPA2,RIGI,KRAS,UFM1,HINT1,HSD17B10,DHX9,PCNA,EWSR1,SDHC,RAB4A,PLS3,PIR,EZH2,MSX2,SOX2,RAP1A,FEN1,RAF1,FASLG,SUMO3,RHOH,RAC2,CD274,COTL1,ST3GAL4,HSPB1,CDKN1B,AGR2,PSMD10,RHOG,HDAC6,BAK1,ISYNA1,PDIA3,ADRB2,FBXW7,UCHL3,EP300,CSTB,SIRT7,RPS28,BAP1,RPA3,UBE2M,STOM,RPA2,LMNA,JUP,CDC42,PAFAH1B1,ACTL6A,APEX1,ESR2,CBX5,TXN,MSN,TRIM24,UBE2I,ENO2,CCNF,MDH1,IGF2BP1,LGALS8,RHOB,FAS,MTPN,RAB11A,CUL3,HNRNPAB,MYC,CSK |
| 2.072e-05 | -10.78 | VAMP5 (vesicle associated membrane protein 5) | protein interactions | 10791 | 167 | 72 | 19454 | 5460 |
TMX3,SNAP23,STX18,RINT1,STX8,PTGES3,RFC2,MDC1,VAMP8,TOM1,CSE1L,ERLIN2,TNPO2,SNAP29,IMP3,TMEM14B,STX12,NHERF1,PTRH2,TFRC,TMEM31,STX5,COMT,TMEM45B,STX6,VAMP7,SNAP25,FNDC9,VTI1B,XPO1,LRFN3,PLAC8,MICB,OSBPL8,STX1A,TM4SF18,BET1L,JAGN1,TMX2,GRAMD2B,STX7,NAPG,GOSR1,YKT6,IL6ST,SEC22B,ING5,GOSR2,BET1,FAM234A,ACTL6A,GSTP1,STX17,USE1,LMNA,STX10,RETREG3,GLIPR2,CYB5R3,ELOVL4,VAMP3,SEC63,ATP6AP2,SNRNP40,STX16,HMOX2,BTF3,NAPA,SCFD1,SLC38A1,TAS2R5,TMEM106C |
| 2.095e-05 | -10.77 | SLC25A11 (solute carrier family 25 member 11) | protein interactions | 8402 | 219 | 90 | 19454 | 5460 |
PEX3,RHOG,AGR2,CTNNB1,DDRGK1,BABAM1,KRBOX4,ELK1,EGLN3,BRD9,PHB1,POLR2C,PDHA1,SOX2,TUBA1A,RAF1,TOP3B,MAGEB10,FLOT1,G3BP1,VDAC1,NDUFA4,LAMTOR1,MYC,CUL3,MAD2L2,ESR2,ACTB,VDAC2,BAD,RND2,CDKN1A,FBXO42,COIL,G3BP2,EMC1,UFL1,STAU1,YTHDF1,ADRB2,HSPA8,HDAC5,NMRAL1,RAB5A,AKAP1,UPF3B,FBXW4,SHC1,HDAC6,DPP4,LMAN1,TMPO,RAC2,AIFM1,FURIN,UBL4A,INSIG2,SOCS2,MDC1,PPP1R1A,FAF1,MAP1B,SLC25A11,UBE2H,RC3H2,FBXO7,USP14,SLC25A1,VIRMA,CTSB,MGST3,RHOJ,YES1,GSK3A,WDR45,CCNF,SMAP2,HEXIM1,PRKCA,RPA2,GRM2,CDC42,CFTR,CDK7,HSPA5,NF2,FBXW7,RNF113A,SQSTM1,RPA3 |
| 2.096e-05 | -10.77 | RABGGTA (Rab geranylgeranyltransferase subunit alpha) | protein interactions | 5875 | 82 | 41 | 19454 | 5460 |
LAMP3,ATG7,GAPDH,BTF3L4,RAB32,RAB5C,VPS26A,SEC13,PFDN2,IRF6,RAB3A,PPP1R16A,RRAS2,RAB9B,EIF2S2,RAB31,HRAS,ILVBL,RAB33A,APEX1,RAB1B,SERPINA3,ETFB,EEF1E1,RTF2,RAB4A,RAB6B,BMPR2,RABGGTB,RAB30,RAB27A,RAB5A,VPS26B,RAB9A,RAB1A,PYM1,PPP1R12A,RAB29,YKT6,KRAS,GPIHBP1 |
| 2.096e-05 | -10.77 | Mapk13 (mitogen-activated protein kinase 13) | protein interactions | 26415 | 82 | 41 | 19454 | 5460 |
PLS3,HSP90B1,GDI2,EEF1A1,EEF2,RPS14,CCT5,TFG,HSPA5,G3BP1,EIF5B,HNRNPK,PGK1,PDIA6,DHX9,PRDX6,GFM1,PABPC1,CCT8,DDX1,YWHAB,CCT2,CKB,YWHAZ,ATP5F1A,HNRNPA1,GAPDH,NONO,PDIA3,PGAM1,LDHB,TMPO,CACYBP,TAGLN2,LDHA,GANAB,RPLP2,RPS3,EEF1B2,ENO1,RAN |
| 2.096e-05 | -10.77 | EXOC6 (exocyst complex component 6) | protein interactions | 54536 | 82 | 41 | 19454 | 5460 |
EXOC5,P2RY10,EXOC1,DSN1,GPR17,RAB11A,FAM174A,CUL3,EXOC8,EXOSC1,EXOC2,PSMD14,ALB,SCN2B,LMBR1L,CHRM4,APLNR,PRDX2,NPY2R,FAM234A,IL1R2,RAP1A,CARD19,GNAQ,SIGLECL1,RPA2,CYP2C8,CA14,EXOC3,VPS33A,SAMM50,EFNB1,CXCR4,NAE1,RPA3,PSEN2,STX11,STX7,NPTN,CD80,SEMA4C |
| 2.099e-05 | -10.77 | RAC3 (Rac family small GTPase 3) | protein interactions | 5881 | 615 | 219 | 19454 | 5460 |
PPP2R1A,IFNGR1,LGR4,MACO1,DLG3,STX12,RPN1,STIM1,PCDH17,JAK1,MAP3K11,AHCYL1,FLOT1,EMC8,WDR11,TAF7,PIK3R1,SLC20A1,GJA1,WDR6,PLAC9,PPIA,TMEM237,OCRL,SPTAN1,EHD1,NOTCH2,DAAM1,ELOVL1,VAPB,ARMCX3,DUSP9,CXCR4,EXD2,STX7,CYFIP2,GPM6A,MAP3K21,MRPL16,NIBAN2,VEZT,PKP4,SLC7A11,SCFD1,YWHAZ,LMNB1,AP2M1,CLDN3,FZD6,FAM91A1,CHCHD3,LRRC8A,LAMTOR3,SLC29A1,LBR,MTARC2,CCDC47,CIBAR1,ZDHHC8,KRIT1,HSD17B10,EMC2,SNAP23,NSDHL,RAB1A,STX8,GARRE1,DLG1,ADD2,DAG1,RAB23,TMEM199,RELL1,OSBPL8,SLC2A1,POR,ESYT1,C2CD2,CDCA3,HACD3,SRPRA,PTPN1,EHBP1,CAV1,ALCAM,RPL35A,CGAS,HACD2,ARHGAP1,PIP5K1A,SEC22B,ADIPOR1,SNRPN,JUP,CTDSP1,SLC12A2,GOLGA5,PICALM,STOM,ITGA2,MAVS,MTDH,TMEM209,CDC42EP4,SLC7A1,B2M,NF2,YKT6,PIK3R2,DEPDC1B,AR,RACGAP1,EPHA2,LRP6,ZSWIM7,SLC11A2,GAB1,VAMP3,CTNNA1,FERMT2,SH3BP4,YES1,TMEM59,STBD1,PTRH2,EFNB1,CDK5,GNA11,VAMP8,RAB18,ROCK2,SLC20A2,OLR1,PPFIBP1,YWHAG,DDRGK1,TENM3,CTNNB1,DDX50,WWP2,YWHAB,ARHGAP5,STX5,RAB35,SWAP70,VAMP7,IL6ST,YIPF5,USP6NL,PAK2,SDC2,BMPR1A,GNB4,ITGAV,ABCC5,PACSIN3,EMC1,STX16,SLC30A5,MYC,EPS8,SLC38A1,LAMTOR1,FAM83B,RRAS2,ATP6AP2,NCKAP1,SNAP29,TFRC,PIK3CA,EXOC3,BMPR2,PALM2AKAP2,SLC6A8,FKBP8,AKAP12,SRPRB,SLITRK5,NOS1AP,SLC39A10,ADD1,RAP1B,FLRT2,RAC2,ITGA6,UBE2G2,SLC38A2,STX6,TMPO,LMAN1,VTI1B,ARL6IP5,FCHO2,CDC42,FBXL19,SPTBN1,GIT2,CSNK1G3,LEMD3,SDCBP,SSR1,RAB9A,ARFIP1,LRP10,ITM2B,ARHGEF6,CLDND1,FTSJ1,ARHGAP21,GORASP2,RAB2A,SLC25A1,ATP1A1,ATP1B3,RAP2C,CISD1,STX10,NECTIN2,ROCK1 |
| 2.107e-05 | -10.77 | GJD3 (gap junction protein delta 3) | protein interactions | 125111 | 452 | 167 | 19454 | 5460 |
SRPRB,FKBP8,CTNND1,SLC6A8,DLG1,NSDHL,RAB1A,PALM2AKAP2,STX8,RUSF1,SNAP23,TMX3,YIF1A,STX18,TMEM165,TFRC,PREB,CCDC47,SNAP29,UBIAD1,SLC29A1,LBR,ALCAM,ARL6IP5,DNAJC1,COG1,CAV1,TMPO,SLC38A2,LMAN1,CAMLG,EHBP1,HACD3,SRPRA,PTPN1,CDCA3,SLC39A10,ESYT1,SLC2A1,POR,AGPAT1,OSBPL8,NUS1,DHRS7,TMEM199,RELL1,RAB23,HM13,USP8,CERS2,YKT6,NLGN1,TMEM209,RAB29,TEX264,LRRC8D,RTN4,ITGA2,SQSTM1,ARFIP1,MTDH,SPCS2,TMX4,SLC12A2,GOLGA5,STOM,SSR1,USE1,JUP,LEMD3,PDCL,ARHGAP1,SEC22B,UBA52,SPTBN1,RABL3,CNP,ST7,SLC35E1,YES1,SEC63,VKORC1L1,FERMT2,SMAP2,NECTIN2,CDIPT,VAMP3,GAB1,SRP54,ARFGAP3,ATP1A1,EPHA2,SEC13,GORASP2,SLC6A6,HMOX2,DEPDC1B,SEMA4C,NUP42,SLC20A2,EMC8,RETREG1,SAR1B,SLC35A2,TMEM87A,SCD5,EFNB1,RPN1,STIM1,VAMP2,HGS,PLD3,ARFGEF1,MACO1,STBD1,IFNGR1,YIPF3,FAF2,SPTAN1,WDR6,STX5,CYB5A,GJA1,CDK5RAP3,PTDSS1,DDRGK1,PPFIBP1,NSFL1C,RER1,UFL1,GOSR1,ATP2C1,BET1L,TXNL1,VAPB,TMEM115,ARCN1,TOR1AIP2,BET1,NOTCH2,PGRMC1,GOSR2,USP6NL,GJC1,TOM1L2,RAB6A,PSMD4,ATP6AP2,FAM91A1,ARF1,FAM83B,GGT7,SLC30A7,MYO6,LMNB1,LAMTOR1,VMP1,ZMPSTE24,SCFD1,SLC38A1,PKP4,RAB11A,NIBAN2,VEZT,TMEM38B,SLC30A5,PSMD1 |
| 2.113e-05 | -10.77 | LTV1 (LTV1 ribosome biogenesis factor) | protein interactions | 84946 | 190 | 80 | 19454 | 5460 |
AHCYL1,RPL17,RPS13,MEPCE,G3BP1,KRAS,H3C1,SRSF7,RPS24,DNAJB4,MAP1B,RPL31,RPS11,RND3,DNAJC2,SOX2,OTUD6B,RPSA,RAF1,ZBTB2,CEP19,RBM42,EGLN3,DIRAS3,CGAS,SPPL3,RPS10,FZR1,DNAJC1,RPS16,NOB1,KRR1,SRSF1,PHB1,SYNCRIP,RPS2,SNRNP70,DDRGK1,API5,HNRNPA1,CSNK2A1,XPO1,G3BP2,STAU1,FBXW7,UFL1,PCGF2,PNO1,DYRK2,HEXIM1,NEK7,ATG16L1,RPS14,SYK,RPL19,RPL10,RPL35,NDN,GTF2F2,RPS20,PTEN,FGFBP1,GSK3A,TUBA1B,LMBR1L,RPS3,CCNF,PPIG,UBE2H,MYO6,FTSJ3,BICD2,RC3H2,DCAF4,FAS,PSKH1,DNAJC8,RIOK2,CUL3,MYC |
| 2.128e-05 | -10.76 | CDC20 (cell division cycle 20) | protein interactions | 991 | 222 | 91 | 19454 | 5460 |
CDKN1A,CKS2,CTBP1,EP300,HSPA8,STAU1,OTUD7B,CUL3,MYC,CREBBP,RIT1,CCT2,ANAPC2,UBE2S,MAD2L2,MAD2L1,TUBB,PPP2R1A,TUBA1A,CKS1B,RAF1,TUBB4B,PCNA,CCT8,HSPD1,HNRNPF,KRAS,DDRGK1,YWHAH,XPO1,YWHAG,CDC26,PPP2R5A,PRDX1,RPL23,HAX1,CDC23,SPINT2,SOSTDC1,PLEKHO2,PPP2CB,FBXO31,CCT7,EGLN3,TCP1,CCNA2,NEK2,RPS14,CDR2,SAMM50,IDH2,FGFR1,RPA2,CDK1,RNF34,ANAPC16,RPA3,HSPA5,SLC25A51,GMNN,ANAPC15,CCNB1,CDC16,PTTG1,ANAPC4,SPOP,PPP2R5E,CCNF,RPS3,UBB,CDC20,BUB3,CCT5,TBK1,MAD2L1BP,MDC1,H3C1,ANAPC11,HUWE1,HDAC6,COPS5,MOV10,ID1,TUBG1,TAS2R13,MYBL2,MCL1,MXI1,CDC5L,CDK9,FZR1 |
| 2.136e-05 | -10.75 | NHLRC2 (NHL repeat containing 2) | protein interactions | 374354 | 372 | 141 | 19454 | 5460 |
RSRC1,RAN,SNRPD2,DYNLL1,RPL35,GPNMB,TRIM29,LGALS3,PSMB6,FMC1,MCM3,GGH,BLVRA,ATG3,MYO6,S100A11,CHTOP,TNFAIP8,RIT1,PEBP1,TTC1,PSMA3,TRA2B,SRSF2,SRM,SRI,CSRP1,MRPS7,SYK,DUSP14,PAFAH1B1,PRDX3,CRYAB,HEXB,ARCN1,CNDP2,ANXA7,HOMER3,PSMB4,ANXA4,FAM98A,MPP1,SNRPD3,EGLN3,GLRX,CHMP2A,RAB32,PDIA3,VPS26A,NT5C2,RHOG,FKBP4,AGR2,PDCD10,ZYX,ARHGAP15,HNRNPF,KRAS,PSMA1,VAMP8,MSL2,IMPA2,ARFGEF1,OTUD6B,PPP2R1A,BPIFB1,GDI2,CTSA,JPT2,CCNF,EIF2AK2,PSMA6,GANAB,PRKRA,EIF2S2,MGST3,CTSB,PNP,RAB14,MAGOHB,HOMER1,IDE,CTTNBP2NL,GNAI2,VIRMA,PLEKHF1,FAH,TFEB,CTSD,SEC13,SORD,SNX5,UBE2H,PPIG,RPA3,BAP1,PGK1,PRDX6,NF2,PCK2,CAPN1,PIP5K1A,RPA2,SCLT1,GSTP1,CYC1,HCLS1,SYNCRIP,HSD17B11,RB1,RAC2,PSMB1,CPNE1,VPS26C,LCP2,LMAN1,RASGRP2,IAH1,SLC25A12,G6PD,GLO1,LYPLAL1,DNAJC7,SLC25A11,ZNF451,TCOF1,RAB27A,CAMK2G,HUWE1,PSMA5,OLA1,RPL17,CTSC,TBK1,SNAP29,PREB,TP53,MAP2K3,VAC14,ILF2,APEH |
| 2.139e-05 | -10.75 | response to ketone | biological process | GO:1901654 | 218 | 93 | 18204 | 5365 |
UCP2,TGFB2,ROCK2,CALR,PTGFR,HNRNPD,GJB2,AANAT,PCNA,OXTR,P2RY4,GNB1,AKT1,AIFM1,CLDN4,SPP1,TGFB3,NKX3-1,DDIT4,FBP1,CCR7,HDAC6,BCL2L1,JAK2,FOS,SPHK2,CDKN1A,WBP2,GAD2,PRKCE,ADCY2,TYMS,ACACA,RPL27,NEFL,CFTR,CD38,CCL21,TLR2,CYP1B1,CBL,CCL19,VPS54,AR,CDK4,MSN,FOXP1,PIK3CA,F7,UBE3A,PTGER2,HPCA,EIF4E,FBXO32,IGF1R,CREB1,SFRP1,BGLAP,KCNJ11,ATP5F1A,COMT,SRC,FOXP3,ERRFI1,HSPA8,GNG2,KLF9,KLF4,FIBIN,ABHD2,ELK1,SMYD3,AKR1C2,PAX6,ADCY3,SIN3A,EPO,CAV1,USP8,TXNIP,EFNA5,MSTN,PCK2,NQO1,TSPO,RWDD1,TACR1,MIR342,MTAP,LIPA,SP1,CLDN1,PTGER4 |
| 2.140e-05 | -10.75 | protein polyubiquitination | biological process | GO:0000209 | 249 | 104 | 18204 | 5365 |
NT5C2,UBE2W,FBXO9,WDR77,MUL1,CTNNB1,TRIM32,TNFAIP3,UBE2L3,TRAF1,TRAF2,TRIM62,IRF2BP1,KBTBD6,BIRC2,TRIM6,TRIM8,UBE2V1,UBE2V2,STUB1,BFAR,UBE2G2,ANAPC13,RNF8,RNF5,HDAC6,RNF167,TRIM5,UBE2E3,ANAPC11,PRPF19,SYVN1,RNF152,FBXW11,RNF126,TRIM22,RNF144B,TRAF6,CBL,TOPORS,SKP1,RNF26,UBE2N,UBE2D1,CDC26,DTL,RNF146,MDM2,TRIM68,CDC23,UBE2E2,UBE2K,CDC16,RNF14,UBE3A,WWP2,TRIM45,TRAF3IP2,ANAPC4,FZR1,UBE2D3,TRIM34,SHPRH,PELI3,MARCHF5,WSB1,HUWE1,ANKIB1,RNF34,TRIM21,PELI1,FBXL7,TRAF7,RNF41,TRIM27,UBE2A,FBXO7,IFI27,UBE2H,RBCK1,TNKS,RC3H2,NMI,CBFB,FBXO22,RNF115,ZNRF1,NQO1,RNF20,KLHL3,HECTD1,SPOP,CUL3,SMURF1,RNF187,TRIM3,BRCA1,UBE2B,AREL1,ANAPC2,TRIM26,UBE2S,NBN,TNKS2 |
| 2.150e-05 | -10.75 | extrinsic apoptotic signaling pathway | biological process | GO:0097191 | 112 | 54 | 18204 | 5365 |
IL1B,ACVR1B,IL12A,DELE1,RB1CC1,PRDX2,TNFSF12,ITGAV,FASLG,SMAD4,STK3,RNF41,GABARAP,PARP2,IFNG,BOK,RAF1,SMAD3,TLR3,IL1A,STK4,CX3CL1,TGFB2,BLOC1S2,TNF,PDIA3,DAPK1,SFRP1,BAK1,BAX,FGF10,MCL1,MLLT11,FAS,CTNNA1,BAG3,PIK3R1,TNFRSF1B,SIVA1,BEX3,IL2,PML,BCL2A1,IFI27,JAK2,BCL2L1,CTTN,DEDD,BAD,IL7,G0S2,KRT8,CRADD,GSK3A |
| 2.150e-05 | -10.75 | SUCLA2 (succinate-CoA ligase ADP-forming subunit beta) | protein interactions | 8803 | 170 | 73 | 19454 | 5460 |
METAP2,CCDC90B,DLST,CCNF,IRF2,TACO1,ESR2,SUCLG2,TUFM,CFL2,PMPCA,CUL3,AUH,MTG2,ZMYND19,RAB2A,HTRA2,MDH1,PSMD14,GFM1,HSPA8,EXD2,IDH3A,RPA3,DNLZ,GRPEL1,NT5C3A,OXCT1,FBXW7,HSCB,STXBP1,MRPL12,CFTR,SEC22B,AGTRAP,MTRES1,RPA2,LMNA,GATD3,TES,SEC23A,SDHB,SSBP1,EGLN3,HNRNPL,ACP6,DHRS7,MTRF1,GRSF1,MRPS26,TMEM70,RHOG,COX8A,MKLN1,HINT2,MAEA,HSPD1,SAR1B,ABHD10,RAD21,IMMP2L,FASTKD5,ETFA,REXO2,METTL15,DIRAS1,FAF2,MRPL11,RRM1,RAF1,SOD2,PDHA1,EZH2 |
| 2.158e-05 | -10.74 | SEPTIN11 (septin 11) | protein interactions | 55752 | 106 | 50 | 19454 | 5460 |
DYRK1A,VIRMA,ESR2,FERMT2,VDAC2,CCNF,RHOB,CHORDC1,UFD1,TOMM40,OXCT1,STAU1,TMEM177,CDC42EP4,RPL27,BAP1,SEPTIN6,RPA3,DNAJC3,EP300,FGFR1,RPA2,CSNK1A1,SEC22B,MRPL12,CFTR,CDC42,MORN4,PRNP,HNRNPL,ARF6,CDK9,PRCC,HRAS,SIN3A,RB1,PEDS1,TST,KRAS,MPST,AP1M1,TCOF1,SCYL2,CDK5,SEPTIN7,MAD2L1BP,NDUFS6,STIM1,SH3GLB1,MAP1LC3B |
| 2.167e-05 | -10.74 | MED1 (mediator complex subunit 1) | protein interactions | 5469 | 193 | 81 | 19454 | 5460 |
CBX3,CDK8,EZH2,CASK,BIRC5,TAF2,POLR2D,POLR2C,POLR2G,TP53,MED9,VDR,RAF1,RPAP2,PPARA,SOX2,THRAP3,POLL,TRIP4,EMC2,MED29,MED21,MED27,DICER1,BRD3,MED4,CDK12,YWHAH,POLR2I,CDK9,MDM2,POLR2L,RBM5,GTF2B,ZNF326,CTBP1,MED23,RPA2,PPARG,MED31,ZNF574,TFIP11,HEXIM1,SUPT7L,ATG16L1,CDKN1A,CDK7,SUPT3H,MED30,FBXL19,STAU1,FBXW7,MED11,EMC1,PML,RPA3,NR1I3,NUP50,EP300,MED13L,STN1,MED10,SETD7,POU1F1,HNRNPC,MED22,MYC,CTSD,AR,BAG3,RUNX1,PSMD6,GABPA,NR1H2,MED17,PSMD4,ESR2,VIRMA,POLR2B,GTF2F2,POLR2F |
| 2.167e-05 | -10.74 | PRDX4 (peroxiredoxin 4) | protein interactions | 10549 | 193 | 81 | 19454 | 5460 |
EZH2,CHMP4C,H2AX,DNAJC25,CSNK1E,RAF1,UBL4A,E2F4,RIGI,PRDX4,HUWE1,EWSR1,POC1B,RPAP3,CBL,TUBG1,AGR2,HDAC6,DDRGK1,DPP4,IFI16,PRDX1,MOV10,ZNF593,EGLN3,PLG,DNAJB9,ARHGAP25,EED,MAP1LC3A,PTPN1,RCHY1,UBE2M,HEXIM1,PIH1D1,PTP4A2,PSMB7,RPA2,PPT1,HSP90B1,SEC62,PRDX3,CDK7,WDR5B,UBA52,FBXO42,EIF4E,HSPA5,UFL1,ARHGEF39,HDAC5,CRY1,HSPA8,HADHA,PMAIP1,RNF113A,EP300,AKAP1,BAP1,DVL2,RPA3,DNAJC3,SOD1,SIRT7,UBE2H,DNAJC10,AR,MYC,CUL2,PYCR2,CUL3,SFN,PYCR1,VIRMA,COPE,CYP27A1,PRDX2,CTSB,SEC61B,CCNF,ENO1 |
| 2.167e-05 | -10.74 | OAT (ornithine aminotransferase) | protein interactions | 4942 | 193 | 81 | 19454 | 5460 |
OAT,UBE2H,HTRA2,MDH1,RSPH1,ACO2,AUH,MYC,MTG2,PMPCA,TXNRD2,CUL3,LDHB,CUTA,PDE4B,SAMHD1,DNAJC5,VIRMA,TACO1,OPTN,CCNF,DLST,MTG1,ENO2,PITPNB,SMU1,PTEN,ADSS2,RPA2,OXSR1,UBE2M,SLC35F6,UBA52,NUDT3,HSCB,RER1,STAU1,NSFL1C,ADRB2,OXCT1,RPA3,SOD1,SIRT7,HDAC5,RTN4,GFM1,NME2,PPM1B,SNRNP70,YWHAB,GRSF1,GMPPB,HDAC6,ESD,AIFM1,SSBP1,CD274,PHB1,DUSP6,PREP,AKR1B1,GATD3,EZH2,TFCP2,CTSA,PPID,PDHA1,SOD2,FAF2,PGM1,G3BP1,HUWE1,REXO2,TF,ABHD10,HSPD1,FAF1,HINT2,IDH1,AGA,COX8A |
| 2.174e-05 | -10.74 | Type II interferon signaling (IFNG) | WikiPathways | WP619 | 37 | 26 | 5310 | 1910 |
PSMB9,IRF1,OAS1,STAT2,ICAM1,SOCS3,CXCL9,STAT1,IL1B,IFNB1,IFNG,IFIT2,IRF9,REG1A,IRF8,CXCL10,ISG15,IRF2,IFI6,JAK2,PTPN11,IFNGR1,EIF2AK2,IRF4,IFNA2,JAK1 |
| 2.188e-05 | -10.73 | STXBP2 (syntaxin binding protein 2) | protein interactions | 6813 | 90 | 44 | 19454 | 5460 |
HSP90B1,VAMP2,CNDP2,CCR1,CENPM,WDR5B,GGCT,JUN,CERS2,HNRNPA0,IL1B,BCL6,CERS6,RIGI,TUSC3,STX11,HNRNPA2B1,GLUL,RPA3,SOD1,BAP1,PEBP1,SNAP23,BAG2,EP300,SLC39A7,STX1A,PTPN11,FAM174A,PLPP4,GMPS,SNRPB,SNRPD3,DYNC1I2,KCTD10,CTSB,PHTF2,RAN,PAPSS2,S100A6,SSU72,SNX17,SNRPD2,GJA1 |
| 2.188e-05 | -10.73 | THOP1 (thimet oligopeptidase 1) | protein interactions | 7064 | 90 | 44 | 19454 | 5460 |
HNRNPL,CHMP2A,IDE,MYG1,EIF4E2,OPTN,SSU72,DCK,CHRAC1,AGR2,PSMG2,UBE2H,SORD,MPHOSPH6,EXOSC1,DDX1,STK11,CUL3,DIS3L,TOLLIP,HSPE1,OXCT1,RBBP7,PYGB,MAPKAPK3,PPM1G,HSPD1,RPA3,IDH1,EXOSC4,ABCE1,EXOSC3,NME1,VAV2,ADSS2,RPA2,PLS3,UAP1,PALS2,CBX3,PIH1D1,TXNRD1,EXOSC8,TRAF2 |
| 2.188e-05 | -10.73 | ERH (ERH mRNA splicing and mitosis factor) | protein interactions | 2079 | 228 | 93 | 19454 | 5460 |
CFTR,CDK7,UPRT,SF3A1,HEXIM1,UBE2M,ZNF574,WWP1,RPA2,CDK1,RNF113A,RPA3,SLC39A9,HSPA5,DGCR8,DNAJC8,PPP1CC,UBE2H,RC3H2,CSNK2B,PSMA6,EIF4A3,CCNF,YES1,LBR,CD2BP2,TP53,UBL4A,FBP1,SNIP1,SMN1,MEPCE,THRAP3,ZNF200,GTF2E1,HDAC6,CSNK2A1,TLE1,SNRNP70,TES,ALYREF,CTDSPL2,ZBTB2,RBM42,TOP1,ELK4,MED31,RAB5A,SF3B1,HSPA8,DDX39B,SNRPA,ASB3,IGSF21,GPC1,UFL1,EIF1B,SNRPB,BTF3,RNF40,MYC,ILK,RIT1,LMNB1,CHTOP,FYTTD1,INTS10,VPS72,ESR2,ERH,SNRPB2,SUPT5H,RAF1,ZNF263,NGB,EZH2,RTCB,SRSF8,PRDM4,POLDIP3,SSRP1,VDAC1,KRAS,ACP6,DDRGK1,WWP2,MAGOH,CBL,DROSHA,AGR2,DDX23,EED,FOLR1 |
| 2.203e-05 | -10.72 | KDSR (3-ketodihydrosphingosine reductase) | protein interactions | 2531 | 98 | 47 | 19454 | 5460 |
DDX39A,ATP5PB,TSPAN3,STX12,ACADSB,RPN1,YIF1A,LPAR2,TSPAN17,ATP5PF,NDUFB5,RAB1A,SLC6A8,FKRP,COA1,KRAS,PGAM1,RELL1,CD63,TLCD4,RAMP3,TNFSF18,VTI1B,RAB1B,HCST,OTULINL,SLC19A2,FUT8,GOLGA5,GPR35,RPA2,NDUFC2,SLC35F2,RABAC1,TSPAN15,RPA3,HSDL1,CERS6,TSPAN5,LPAR1,CERS2,REEP6,SARM1,ACP2,B4GALT3,MGAT1,ATP5F1B |
| 2.203e-05 | -10.72 | FAM210B (family with sequence similarity 210 member B) | protein interactions | 116151 | 98 | 47 | 19454 | 5460 |
VAMP1,HCST,PLP2,CCDC167,BET1,TIMMDC1,HEXB,TIMM23,SMCO4,EMP3,RTN4,TSPAN15,TSPAN5,STX7,LPAR1,HMOX2,SLC35B4,TM4SF20,REEP6,FIS1,CYB5R3,STUM,VAMP3,TIMM8A,INSIG2,CYB5B,CRELD1,TFRC,YIF1A,TSPAN17,ATP6V0B,FSTL1,PLPP6,TF,FAM241A,TMEM107,TMEM19,TSPAN10,SYNJ2BP,ADGRE2,TMEM11,ARL2BP,CD63,RPRM,STX6,EIF2B5,SPPL3 |
| 2.216e-05 | -10.72 | UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) | protein interactions | 7386 | 231 | 94 | 19454 | 5460 |
NDUFAB1,CRAT,MPV17,CYC1,TFB1M,CDK1,RPA2,GFM1,MGAT4B,TXNDC17,RPA3,ABCC2,SLC25A51,NME4,CIAO1,CTSD,OAT,ACAT1,PTPMT1,ACP2,UQCRQ,RAB14,BCS1L,PGM1,APOO,OSGEPL1,GFM2,NHERF1,NDUFS3,SFXN1,ATP5PF,MPST,FKBP8,CHDH,ATP1B1,COPS5,MOV10,TMEM70,NDUFB4,COX4I1,SDHB,SSBP1,CDK9,ILVBL,ISCU,PAFAH1B1,MAP2K1,ACAA2,FOXS1,VAPB,ADSS2,HSPA8,PDSS2,ATP5IF1,EXD2,OXCT1,HSCB,EMC1,TM9SF4,MRM2,TXNRD2,CUL3,MTG2,AUH,COX6B1,MDH1,PDF,BRCA1,TAFAZZIN,PELI3,MTG1,TOMM7,CYB5B,NDUFA12,PDHA1,NDUFS6,NUDT19,HINT2,NDUFA4,BCKDK,PREPL,AP1M1,XPNPEP1,KRAS,G3BP1,CBR4,CLPX,NDUFB8,AGR2,GSTO1,SDHAF2,HDHD5,MACROD1,UQCRH |
| 2.226e-05 | -10.71 | FERMT2 (FERM domain containing kindlin 2) | protein interactions | 10979 | 173 | 74 | 19454 | 5460 |
ARL15,RPA2,PICALM,FGFR1,ISOC1,CDC42,EHD3,CLDN4,STX7,STAU1,GREM2,RAB5A,RAB9A,RPA3,RHOU,IGF2BP1,NTRK3,ILK,LAMTOR1,WDR20,F9,RHOB,BICD2,YWHAZ,DNAJC5,RAB2A,NAA50,MYC,TXNRD2,RAB11A,MAT2B,SMURF1,DYRK1A,APEX1,SRC,RHOJ,SNRPD1,CTNNA1,RND3,MOB3C,SOX2,TP53,FLOT1,PTGES3,KRAS,EPHA4,HNRNPK,IGF1R,ZYX,DDX1,UBFD1,PDCD10,RHOG,YWHAH,LAMP3,XPO1,CTNNB1,GAPDH,LAMP2,RAB5C,DIRAS3,CNTROB,CEP19,CAV1,MARCHF4,G0S2,ARF6,TRIM15,RHOH,GJA1,RAC2,DFFA,HRAS,RAB35 |
| 2.226e-05 | -10.71 | POLR2G (RNA polymerase II subunit G) | protein interactions | 5436 | 173 | 74 | 19454 | 5460 |
POLR1H,FBXW7,MED11,PPP1R2,TCEA1,MED13L,ELOF1,SNRPA,PIH1D1,MED31,WWP1,TRIM68,RPRD1B,POLR1D,MED30,TPT1,UPRT,SRC,DES,ESR2,POLR2B,MED17,POLR3H,GTF2F2,POLR2F,MCPH1,GTF2F1,POLR3B,PRKRA,EIF4A3,POLR1B,RIT1,CDC73,PFDN2,BRCA1,MED10,MED22,COX6B1,LMO2,SSRP1,PDRG1,PHF1,DNAAF10,KRAS,FAM168A,NTRK2,EWSR1,RPAP3,POLR2D,POLR2G,POLR2C,GTF2E2,RPAP2,PSMB9,KIF1C,SUPT5H,MED9,CIB3,POLR2I,TOP1,EIF2S1,POLR2L,RPRD1A,GTF2B,MED4,TRAPPC2L,MED29,MED21,FOSL2,MED27,EIF3D,XPO1,GTF2E1,WWP2 |
| 2.239e-05 | -10.71 | membrane raft | cellular component | GO:0045121 | 290 | 117 | 19108 | 5553 |
RAP1B,ADD2,ADCY2,STX12,CD14,IKBKB,HTR2A,BACE1,TGFBR2,VDAC1,ANGPT1,SLC6A3,DAG1,CAV2,EFHD2,CTNNB1,CD36,STOML2,GJA1,BAALC,ATP2B4,EEIG1,CHRNA7,CHP1,DLG1,CDH13,ERLIN2,CD4,RANGRF,TRAF2,TLR1,CNR1,FLOT1,ATP1A1,IL6ST,ADTRP,SLC2A1,LAMTOR1,TNF,PLSCR1,SLC22A6,HDAC6,SLC1A1,LCP2,OLR1,CD1A,CAVIN2,JAK2,PPT1,LAT2,SRC,TLR2,ICAM1,HYAL2,BMPR2,KCNMA1,SLC1A2,ADGRG1,RAB5A,RIT2,NOS1AP,ATP5F1A,TLR6,SMPD2,CHRNB2,CLIP3,DPP4,EMP2,TNR,EFNB1,SLC6A4,TNFRSF1B,IGF1R,ADRA1A,BVES,FURIN,CORO1C,LDHB,FASLG,EFNA5,BMPR1A,SDCBP,ERLIN1,MME,RAP2B,PGK1,LRP6,KCND2,SERPINH1,STOM,PRNP,FAS,GPM6B,BCL10,CAV1,GPC1,BST2,THY1,STOML3,S100A10,CD226,PSEN1,CBL,CAV3,CAPN2,LYPD6,CTNNA1,STIM1,CTSD,SPRED1,TFPI,MLC1,ABCG2,RGMB,TUBB,ATP1A2,KCNA3 |
| 2.241e-05 | -10.71 | STIM2 (stromal interaction molecule 2) | protein interactions | 57620 | 128 | 58 | 19454 | 5460 |
LIPA,IGF1R,TMT1A,CYP2C9,SAR1B,FKBP8,RAB3B,KRAS,DDX39A,DNAJC25,HEXA,MSRB3,PRKAG1,SFTPC,PTRH2,RPN1,STIM1,RAC2,HSD17B11,GJA1,RAB35,PTPN1,CD1A,TMPO,STX6,EGLN3,LMAN1,DNAJC1,YWHAG,YWHAH,SLC25A46,YWHAB,ESYT1,RHOG,RAB9A,DERL1,SYVN1,STX7,PXMP2,ST7,CDC42,SEC62,OTULINL,RND2,TMEM106A,PRKAB1,HEXB,FGFR1,SSR1,SEC61B,RMDN3,SEC63,BRINP3,HMOX2,NTRK3,YWHAZ,LMNB1,RHOB |
| 2.243e-05 | -10.71 | PPIG (peptidylprolyl isomerase G) | protein interactions | 9360 | 117 | 54 | 19454 | 5460 |
SRPK2,ESR2,LGALS3,IFI6,TRIM54,CCNF,MAPRE1,UBE2H,SP1,ZBTB38,CEP70,SNRPB,ANAPC15,CUL3,MYC,SAP18,PSENEN,RNF113A,CLK1,NKAPD1,SNRPA,SLU7,LARP4B,PABPC5,HMG20A,ZBTB2,NUF2,NKAP,SRSF1,ARMC8,ANKRD50,SNRNP70,DDX23,TRA2A,ZMYND11,YWHAG,ZCCHC10,SMN1,SRSF4,THRAP3,FHL3,SRSF7,ZC3H11A,SNIP1,TMEM14B,SART3,NUPR1,RPS11,PNMA2,CHMP4C,TFCP2,NFKBIL1,THAP1,RAF1 |
| 2.248e-05 | -10.70 | PROTEASOME_BETA_2 | prosite domains | PS51476 | 11 | 10 | 12186 | 3388 |
PSMB9,PSMB10,PSMB7,PSMB6,PSMB5,PSMB4,PSMB3,PSMB1,PSMB11,PSMB2 |
| 2.257e-05 | -10.70 | FDPS (farnesyl diphosphate synthase) | protein interactions | 2224 | 156 | 68 | 19454 | 5460 |
DFFA,SSMEM1,G6PD,PRNP,EMC6,HNRNPA1,XPO1,MOV10,EMC4,CDK12,ABCE1,IDH1,IGF1R,EMC2,PSME1,PABPC1,TCOF1,RINT1,SEPHS1,KRAS,ACTN4,PPP2R1A,RAF1,KBTBD4,RRM1,MED9,RANBP1,PPME1,TAF2,PSMC3,PLS3,NME1,CHMP4C,RMDN3,MSN,CCNF,ENO1,PPP1R10,CLIC4,GPX1,PYGM,TRIM29,TUFM,CREB3,MYC,CUL3,SEC13,PSMA4,SORD,SERPINH1,ZMPSTE24,HSPA8,PDSS2,NMRAL1,ATPAF2,RPA3,ATP6V1G1,EMC1,GTF2I,WDR77,STAMBP,ADSS2,PLAA,RPA2,MED23,USE1,ACAA2,FGFR1 |
| 2.260e-05 | -10.70 | FKBP2 (FKBP prolyl isomerase 2) | protein interactions | 2286 | 77 | 39 | 19454 | 5460 |
DPP4,CUL3,LDHB,GSTK1,PPIB,GLOD4,NME2,LYZ,SSBP1,ENO1,ENO2,DSTN,RAB3C,MSN,TAGLN2,TXN,SUMO3,LGALS3,PPIA,RPL19,ATP6AP2,ARFGEF1,HADH,RAB6A,VAMP2,ACAA2,DNAJC2,CARHSP1,C1QC,FKBP1A,TMEM39A,KATNAL1,GPX4,RAP2A,HSD17B10,HINT1,CRYZ,PTGES3,SKP1 |
| 2.270e-05 | -10.69 | FBXO5 (F-box protein 5) | protein interactions | 26271 | 47 | 27 | 19454 | 5460 |
ANAPC2,ENO1,UBE2S,SRC,CDC20,ACTB,FZR1,TPM3,RIOK2,ANAPC15,CDC26,CUL3,MOV10,CDC16,MYC,ANAPC4,CDC23,BRCA1,FBXW11,ANAPC16,SKP1,BACH1,DHX16,ANAPC11,KRAS,ANAPC13,CDK1 |
| 2.283e-05 | -10.69 | Programmed Cell Death | REACTOME pathways | R-HSA-5357801 | 175 | 81 | 10285 | 3229 |
YWHAH,UBB,TLR4,LMNA,UBA52,H1-3,BAX,PSMD14,PRKCQ,YWHAZ,PSMD7,DAPK3,ROCK1,DFFA,KPNA1,PSME1,BAK1,PSMD10,PSMB3,STK26,SPTAN1,PSMA2,PSMB6,SFN,PSMB11,PSMC5,PSMB10,LY96,PSMA5,PMAIP1,FASLG,PSMA4,PSMC4,PSMA3,PSMB5,H1-1,YWHAB,PSMB1,SATB1,PSMD3,PSMB7,TFDP2,PSMD4,LMNB1,RPS27A,TRAF2,DYNLL1,PSMA1,FAS,PSMC3,TP53,CTNNB1,BAD,H1-5,PSMB9,SEM1,CD14,BCL2L1,GAS2,PSMD6,HMGB1,PAK2,PSMB4,TICAM2,BIRC2,PSME2,TNFSF10,AKT3,PSMA6,AKT1,PSMB2,PSMD1,STK24,AKT2,ADD1,YWHAG,TICAM1,PSMD12,PSMC1,TLR3,DAPK1 |
| 2.291e-05 | -10.68 | MRPL28 (mitochondrial ribosomal protein L28) | protein interactions | 10573 | 240 | 97 | 19454 | 5460 |
TUFM,TRAF3IP2,RPL26,UBE2H,ZNF655,MRPL53,RPL13A,SMYD3,RBMS2,NDUFAB1,MRPL10,MTRES1,ZNF574,CDR2,DYRK2,GFM1,APMAP,RPA3,MRPL20,UTP23,MRPL40,MRPL41,MRPL17,USP2,GRSF1,CHCHD1,SNRNP70,TMEM70,PRR3,ALYREF,SSBP1,MRPL24,TEF,MALSU1,MRPL50,METTL15,APOBEC3D,AURKAIP1,MRPL11,MRPL47,MRPL51,MRPL49,GFM2,ILF2,MRPL33,IGF1R,RPL23A,RPL3,MRPL52,RPL17,FASTKD5,MRPL22,H3C1,MRPL16,PMPCA,CUL3,MYC,MTG2,AUH,HTRA2,MRPS25,MRPL13,MTG1,SCNM1,TACO1,RPL19,RPL10,RPL35,MRPL23,MRPL12,RPL27A,MRPS18A,MRPL34,EXD2,NGRN,MRPS7,MRPL57,HSCB,HNRNPA1,MRPL9,MTRF1,HSPB1,MRPS26,RHOG,MRPL18,FAHD1,GATD3,SRSF10,SOX2,HTR2A,RPL18,SRSF7,HINT2,ENKD1,MRPS17,CDCA7L,SRSF4 |
| 2.297e-05 | -10.68 | ERLIN1 (ER lipid raft associated 1) | protein interactions | 10613 | 142 | 63 | 19454 | 5460 |
EDEM1,EMC4,TMEM199,CTNNB1,DDRGK1,ESYT1,OSBPL8,HSPB1,RNF139,PHB1,MYEF2,PTPN1,COQ8A,SEC23A,FA2H,DYNC1I2,RHOH,ASB11,CHMP2A,TMPO,RAF1,B3GNT2,CCDC47,ERLIN2,FAF2,ISG15,DISC1,RHOBTB1,NDUFA12,VDAC1,TRIM37,MYC,DEPDC1B,RHOB,BRCA1,NTRK3,APEX2,LMBR1L,BAD,CHCHD6,RPGRIP1L,COPE,MAD2L2,DUSP3,CFTR,EDEM3,RND2,SEC22A,CDC42,TMUB2,STOM,UBAC2,RPA2,VAPB,TMEM106B,RPA3,SQSTM1,HSPA8,SYVN1,SSR3,EMC1,RNF5,TMUB1 |
| 2.301e-05 | -10.68 | SNRPG (small nuclear ribonucleoprotein polypeptide G) | protein interactions | 6637 | 176 | 75 | 19454 | 5460 |
LSM6,GEMIN8,ZCRB1,CRMP1,PEA15,UBE2H,MYC,CUL3,PRPF31,BTF3,SNRPB,SNRNP40,PSMB6,SNRPB2,SF3B6,RSRC1,METAP2,ZNHIT6,SNRPD1,SNRPD2,MRPS28,PRMT5,SF3B4,ZMAT5,MED23,LSM2,TFIP11,TXNL4A,WDR83,SF3A1,DDIT4L,SNRPN,PAFAH1B1,SNRNP27,RBM22,ATP6V1G1,SNRPA,PRPF4,CWF19L1,SF3B1,PDSS2,DDX23,SNRNP70,MED4,LSM3,RBM17,TLE1,COPS5,DCUN1D1,CAND1,SNRPD3,SNRPA1,TOP1,RBM42,CDC5L,PHB1,LSM10,SF3B5,GEMIN7,SNRPE,SART3,PPP2R1A,CD2BP2,JUN,ESS2,KRAS,SNRNP48,H3C1,TSSC4,CDC40,MEPCE,SMN1,CMTR2,ERG28,FHL3 |
| 2.340e-05 | -10.66 | protein transmembrane transport | biological process | GO:0071806 | 74 | 39 | 18204 | 5365 |
CHCHD4,PEX5L,SEC61G,EDNRA,TRAM1L1,TIMM23,ROMO1,TOMM20,DNAJC19,GRPEL2,SRP54,SEC62,SEC63,RAB11A,ZFAND2B,BLOC1S3,SEC61A2,TOMM40L,TOMM40,TRAM2,HSPD1,AIFM1,SEC61B,MCL1,HSPA8,DNLZ,PEX13,TRAM1,TRIM37,SEC61A1,HSPA5,TOMM22,PEX26,AZGP1,TIMM17A,GRPEL1,TOMM70,TIMM21,TOMM7 |
| 2.344e-05 | -10.66 | chemokine-mediated signaling pathway | biological process | GO:0070098 | 84 | 43 | 18204 | 5365 |
CCR3,CXCL10,CXCL9,CXCL8,CCL5,CCL2,CX3CL1,XCL1,CCL17,CCL18,CCR1,WBP1L,CX3CR1,CCL4L1,CXCL11,CCL24,GPR35,GPR17,GPR75,ACKR3,CXCR3,CCL21,CCR4,CCL3,CXCR6,CXCL12,CCR5,CCL25,CCL23,CXCR1,CCL1,OXSR1,CXCL13,CCR6,CCL11,CCL19,CXCR4,CCL8,CCR7,CCR2,CCL20,CXCL1,CXCL3 |
| 2.351e-05 | -10.66 | MIF (macrophage migration inhibitory factor) | protein interactions | 4282 | 249 | 100 | 19454 | 5460 |
MCM4,CAPG,MYC,LDHB,SCFD1,HSP90AA1,BEX3,MCM8,S100A11,ESR2,AKR1C2,SEC22A,TIMM13,LAP3,PIH1D1,ATP5IF1,RABAC1,COX17,NANP,PEBP1,UFL1,GOSR1,PPIB,DDRGK1,CRIP1,PDIA3,TRIM8,VPS26A,PPM1B,WDR82,IGBP1,HSBP1,HMG20A,PAIP1,COPS7B,RAB1B,SUMO2,JUN,E2F4,SOBP,PIR,NME1,PDHA1,PABPC1,MCM6,AHCYL1,ANP32B,UFM1,NTAQ1,GORASP2,RAB2A,CCNB1,CEP85,CDC73,UBE2H,TRIM24,CCNF,OPTN,STUB1,ZBTB33,ENO1,VIRMA,LDHA,SIPA1L1,SEC22B,SUMO1,SPR,HEXIM1,DYRK2,RPA2,PGK1,DLAT,SOD1,RPA3,BAP1,PML,YKT6,PDHB,OIP5,COPS5,CSNK2A1,CALR,PGAM1,DSTN,LDLR,WDCP,TMED9,MIF,TBK1,KBTBD4,GBE1,TNRC6C,TP53,PPP4C,TFCP2,HINT1,RAB1A,MEPCE,CTNND1,HSPE1 |
| 2.351e-05 | -10.66 | TPR (translocated promoter region, nuclear basket protein) | protein interactions | 7175 | 249 | 100 | 19454 | 5460 |
HRAS,EEF1B2,CD274,TOP1,CDK9,MDM2,CDC5L,SHC1,SNRNP70,RAB1A,HAPSTR1,NUP107,H3C1,RIGI,DUSP19,KBTBD4,TBK1,IK,NUPR1,SF3B6,CCNF,TXN,TMOD3,NDN,DYNLT3,DYRK1A,VIRMA,SMARCA5,PTPN11,AR,TXNIP,BICD2,XPOT,RRP7A,UBE2H,BAP1,RPA3,SOD1,SIRT7,KDM1A,NF2,CDK7,CFTR,LMNA,CDK1,RPA2,GRM2,EED,BUD31,SNRPA1,SUMO2,GLRX,IFI16,RPL6,DDX1,POU5F1,HNRNPA2B1,KRAS,PTPN4,CBX7,UBE2A,RAD21,COPS4,NUP153,NUDCD3,LGR4,GTF2E2,TUBB4B,PDHA1,MOB3C,SART3,RAN,SNRPD1,RPL37A,PHF21A,DYNLL1,MAD2L1,NDUFB7,MYC,RAB11A,PCCB,CIRBP,BRCA1,COP1,THOC6,RIT1,XRCC5,RAB5A,SRSF2,EMC1,STAU1,SAP18,G3BP2,NUP62,NPY2R,SEC62,PRDX3,PCLAF,MAP2K1,CNDP2 |
| 2.363e-05 | -10.65 | protein K63-linked ubiquitination | biological process | GO:0070534 | 57 | 32 | 18204 | 5365 |
RNF8,RNF5,NBN,TRIM5,TRIM27,RNF167,PELI1,UBE2N,TRIM21,UBE2S,UBE2V2,STUB1,BFAR,UBE2V1,HECTD1,TRIM22,PELI3,UBE2B,TRAF6,TRIM3,TRAF2,TRIM32,TRAF3IP2,RNF152,TRAF1,RNF126,TRIM8,RNF115,UBE2E3,WWP2,PRPF19,UBE2E2 |
| 2.364e-05 | -10.65 | regulation of vesicle-mediated transport | biological process | GO:0060627 | 516 | 195 | 18204 | 5365 |
EHD4,SYT4,PSEN1,ATP2C1,AP2A1,OPHN1,IL4,SNX3,CD36,SNAPIN,VPS18,AP2M1,CAV3,LGI3,FERRY3,CAV1,LYAR,CHMP2A,CLIP3,BVES,SNAP91,CDK5R1,FLOT1,RAB9A,APLN,LILRB1,CPLX3,ARFIP1,CSK,CDC42,KCNB1,LRRTM1,CASK,PREPL,FCER1G,MIR185,RAB4A,FGR,RIMS3,IL2RB,MSN,RAB3A,SOD1,PICALM,MIR20A,CCL21,SNX12,CBL,GNAI2,CD14,CPLX2,PRKCB,MAP2K1,HGS,RAB27A,RAP1B,SLC4A8,FCGR1A,CD151,STXBP1,TSG101,PCSK9,NRP1,PLA2G5,RIT2,NR1H2,MIR92B,SNX33,CDH13,VPS4B,ITGA2,GREM1,ARFGAP1,RAB3B,WASL,WNT7A,PPP3CA,P2RY4,VAMP8,TBC1D4,DKK1,RAB29,GH1,RAB3D,IL2RG,RALA,TF,RIMS4,PIP4P2,CALR,PPFIA2,PACSIN3,FCN2,SCFD1,SV2B,SFRP4,BET1L,LYSET,MKLN1,DNAJC5,CPLX1,VEGFA,B2M,LYPLA1,NF2,IL15,SNX17,LGALS3,RNF139,APOC2,AP2S1,CBLL1,DLG4,HNRNPK,VAC14,STX18,RAC2,MTMR2,P2RY1,ITGAV,ARHGAP1,SCAMP5,ANGPT1,HSPA8,PTPN1,SGIP1,CALY,SRC,SYNJ2BP,CLEC7A,ROCK1,HPCA,IL13,EHD1,VPS4A,SDC4,LPAR1,CD47,SDCBP,NLGN1,IFNG,ARF1,CCL19,SFTPD,PICK1,CCR2,YIPF5,ARF6,ADGRE2,PLSCR1,MIR17,CFTR,TBC1D5,MIR183,TLR2,RAB5A,CACNB4,RAB31,IL15RA,WDR44,ATAD1,SYP,CCL2,VAMP2,ATG3,SPHK2,FCGR2B,S100A10,CCDC32,STAP1,STXBP6,PYCARD,MBL2,SYK,RINT1,CLU,MIR205,HMGB1,STX1A,CDK5,RAB11B,VPS28,HFE,RAP1A,KLRC2,FCGR2A,RAB33B,RAB11A,H1-1,LRRTM2,VAMP7,ADIPOQ,ACTB,PPT1,CD63 |
| 2.365e-05 | -10.65 | KAT5 (lysine acetyltransferase 5) | protein interactions | 10524 | 330 | 127 | 19454 | 5460 |
ESR2,LRIF1,GADD45G,ACTB,TAX1BP1,TRIM29,MCPH1,EDNRA,FOXP3,SNRPD2,VPS72,SCFD1,HSP90AA1,BRCA1,FAS,PPP1R16A,ZNF668,CUL3,CREBBP,MYC,ZBTB5,SRSF2,ZNF692,IL1B,IL1A,JADE1,EP300,SAT1,SERTAD2,MED23,PPARG,GKAP1,ACTL6A,CCT7,CCAR2,MEAF6,ZNF511,POLR3F,ODC1,GSTO1,SIAH2,SPATA2,YWHAG,NDUFV2,MDFI,TRIM37,ZBTB14,RUVBL1,KRAS,PTPN4,PCNA,RUVBL2,PICK1,ATF3,RBPJ,CRELD1,UCKL1,H2BC1,ZNF526,SAP30,GTF2E2,SNAPIN,E2F4,MAX,PDCD5,NMI,PRKCE,LDHA,UBASH3B,UBE2I,TRIM27,ZBTB33,CREB1,MAPRE1,TRIM23,CEP70,AR,KPNA6,CCNB1,MORF4L1,RGL2,HDAC3,SQSTM1,CCDC106,NBN,PML,KLF4,TFIP11,HNRNPH3,PLAC1,TRIM68,LMNA,CDK1,CDC42,ING5,FAM161A,SUMO1,UPRT,ZBTB2,TMCC2,KLK3,MDM2,RCHY1,ETV6,H2AZ1,NAP1L5,KPNA1,SSX2IP,H2AC4,MFN1,GAPDH,HDAC6,ZNF24,NFKB1,PTGES3,STX11,H3C1,HINT1,ZNF513,GEMIN7,MAD2L1BP,IK,DMAP1,H2AX,DDX39A,TP53,RRM1 |
| 2.366e-05 | -10.65 | NOS1AP (nitric oxide synthase 1 adaptor protein) | protein interactions | 9722 | 109 | 51 | 19454 | 5460 |
FLOT1,FGF12,SYN3,CAMKV,KRAS,NTRK2,SREK1IP1,PCNA,HSPD1,NUPR1,RND3,NFKBIL1,RP9,AKAP17A,STX6,NKAP,RHOH,GJA1,RAB35,BRD3,YWHAH,XPO1,YWHAG,RAB5C,ZCCHC10,AATF,FTL,NHP2,STX7,STAU1,OIP5,RASD1,PRPF4,NKAPD1,RHOU,ZCCHC17,RND2,ING5,ESR2,VIRMA,DYRK1A,RHOJ,PNP,RALA,AP2M1,SMAP2,NTRK3,PIP4K2C,LAMTOR1,DNAJC5,TOMM40 |
| 2.369e-05 | -10.65 | ARCN1 (archain 1) | protein interactions | 372 | 205 | 85 | 19454 | 5460 |
TES,GJA1,HDHD3,CAV1,CDC5L,EPHB6,CNTROB,EGLN3,HYPK,NOB1,FZR1,ARF6,GOLPH3L,DDRGK1,XPO1,FAM20C,PSMD3,STYK1,AGR2,HINT2,TMT1A,MORC2,ARF4,MCM6,AKAP12,KRAS,PGM1,INSIG2,RAF1,FEN1,RNF181,EZH2,SEC61B,MSN,GANAB,COPZ2,ENO1,ARF1,CCNF,LMBR1L,VIRMA,CLIC4,ARMC6,TMOD3,MATR3,TXN,COPE,USP14,PDE4B,CUL3,PSMA4,ACO2,MYC,UBE2H,NTRK3,TRIM23,GLOD4,EP300,PRDX6,RAB9A,SF3B1,HSPA8,PRKCB,SNRK,WBP2,RPA3,DDX39B,SOD1,PPM1G,BAP1,PXMP2,STAU1,FBXW7,CFTR,NDUFAB1,DDAH1,CNDP2,ARCN1,HEXIM1,UBE2M,GSTP1,IDH2,FGFR1,JUP,RPA2 |
| 2.373e-05 | -10.65 | MINK1 (misshapen like kinase 1) | protein interactions | 50488 | 179 | 76 | 19454 | 5460 |
YWHAB,OSBPL8,NCK1,CSNK2A1,INSYN1,YWHAG,YWHAH,CNOT2,LAMP2,ZCCHC10,CAV1,HNRNPL,ARF6,RHOH,GJA1,RAC2,HRAS,WDR6,RAB35,TNIK,TRAF3IP3,ACTA2,RPL32,ZRANB2,MOB3C,GTPBP1,FNTB,TP53,CNOT6L,PTGES3,FLOT1,CNOT7,KRAS,EFNB1,NTRK2,MAP1B,HSP90AA1,NTRK3,ALKBH5,LAMTOR1,YWHAZ,PKNOX1,RHOB,RIOK2,SNRPB,DNAJC5,NFYA,FGFR1OP2,SUB1,PKP4,SFN,CTTNBP2NL,ESR2,FANCD2OS,RHOJ,DYNLL1,MOB4,CSNK2B,RPL37A,TUBA1B,ARL15,AVPR1B,RPA2,FGFR1,GPC4,PRKAB1,BRIX1,GTF2I,STAU1,HADHA,SQSTM1,STK26,RAB5A,RAP2A,TEX264,CNKSR3 |
| 2.380e-05 | -10.65 | regulation of autophagy | biological process | GO:0010506 | 362 | 143 | 18204 | 5365 |
GAPDH,RRAGB,TICAM1,ATP6V1A,FBXO7,IFNB1,WDR6,CPTP,BNIP3L,LYPLA1,PIM2,CTSA,OPTN,EXOC1,SESN2,IL4,MCL1,TLR9,KLHL22,TSPO,HTRA2,ZMPSTE24,ATP6V1E2,PIK3R2,RAB39B,MTM1,UFL1,IFI16,SCFD1,SNRNP70,TRIM68,GNAI3,TP53,TAB2,TBC1D25,FKBP8,IFNG,CCNY,PIK3CA,ATP6V0B,RRAGA,LEPR,DAPK1,HSPB1,ATG101,NUPR1,USP30,TOM1,ROCK1,TP53INP1,EIF4E,FLCN,SH3BP4,ADRA1A,VDAC1,DRAM1,TRIM34,VPS26B,RB1CC1,TRIM21,TFEB,CDK5R1,WDR45,GPR137,RNF41,DAPK3,LEP,DDIT3,SQSTM1,TRIM27,HAX1,EEF1A1,PAFAH1B2,ATP6V1D,SH3GLB1,TMEM39A,SUPT5H,NLRP6,PHF23,DAP,BAD,CTTN,TRIM23,SLC25A5,PARL,RNF152,GSK3A,BAG3,STK38L,RHEB,TRIM22,MET,CSNK2A1,HSPB8,TBK1,CAPN1,FEZ1,CISD1,TMEM59,BECN1,PIP4K2C,MIRLET7B,EXOC8,ATP6V0E1,SNX18,CRYBA1,BOK,IL10,ATP6V1G2,SVIP,EP300,SNX5,ATG16L1,LAMP3,LACRT,TRIM6,TRIM8,SESN3,TRIM32,SLC25A4,SEC22B,ATP6V1G1,AKT1,RALB,CDK5,ATP6V1C1,ORMDL3,USP13,HMGB1,PTPN22,STUB1,STK11,MTDH,C9orf72,PYCARD,ADRB2,TRIM5,PLEKHF1,FBXW7,POLDIP2,RNF5,VPS26A,HDAC6 |
| 2.385e-05 | -10.64 | RNF125 (ring finger protein 125) | protein interactions | 54941 | 40 | 24 | 19454 | 5460 |
TP53,UBE2W,BHLHA9,TRIM21,EFHC1,JAK1,PML,RIGI,UBE2D3,G3BP1,UBE2K,MYOZ3,CSK,FNDC11,UBE2E2,USP2,NLRP3,UBE2D1,CD274,CTTN,UBE2N,UBE2L3,ACTB,TRIM46 |
| 2.385e-05 | -10.64 | TAGLN3 (transgelin 3) | protein interactions | 29114 | 40 | 24 | 19454 | 5460 |
PMM2,GSTO1,FKBP1B,FABP5,ENO1,ENO2,SNX12,MTAP,TAGLN2,TXN,SUMO3,SNX3,CLIC4,FABP7,GDI2,HEXIM1,FKBP1A,PGK1,HINT1,HSD17B10,YKT6,UFM1,TOLLIP,HSPE1 |
| 2.391e-05 | -10.64 | ATP6V1H (ATPase H+ transporting V1 subunit H) | protein interactions | 51606 | 131 | 59 | 19454 | 5460 |
ARMC6,ATP6AP2,ACOX1,OPTN,VDAC2,CCNF,LMBR1L,RMDN3,BRCA1,ZMPSTE24,ARMT1,IGF2BP1,CUL3,GPR17,RAB2A,NF2,NPTN,ATP6V1G1,HSPA8,VIPR1,ADSS2,TANK,DAAM1,ATP6V1C1,HCST,CDC42,RAB11B,WDR44,RAMP3,CDK9,EGLN3,UBE2N,AIFM1,ATP6V1A,TES,SLC25A28,SLC2A1,ATP6V1D,GMPPB,USP3,LAMP2,SPATA2,FEM1B,P2RY10,ROGDI,CD80,KRAS,LRRN4CL,HSD17B10,AQP3,EZH2,CYB5B,CCR1,ATP5PB,EEF2,SOX9,FAF2,SOX2,MGARP |
| 2.404e-05 | -10.64 | VPS13B (vacuolar protein sorting 13 homolog B) | protein interactions | 157680 | 72 | 37 | 19454 | 5460 |
RAB11A,CSK,UBXN6,COMMD5,RHOG,LAMTOR1,STYK1,H1-1,DNAJC7,HAX1,EEF1AKMT3,CIB2,STUB1,FAM177A1,RAC2,SPEF1,GJA1,RHOH,HNRNPL,CAV1,VIRMA,ESR2,STX6,SNX20,BET1,CSNK1E,RND2,DNAJC25,RAB4A,RAB6B,TMT1A,RAB9A,RAB5A,BAG2,HSPA8,RAB3B,ARL5B |
| 2.410e-05 | -10.63 | EIF3A (eukaryotic translation initiation factor 3 subunit A) | protein interactions | 8661 | 318 | 123 | 19454 | 5460 |
EIF4A2,RPL19,ESR2,RPL10,EIF3K,CMTR1,FAU,RPS9,BRCA1,YWHAZ,RIT1,SETD7,ICAM1,RPS26,CUL3,MYC,RIOK2,TOMM40,STAU1,UFL1,EIF1B,G3BP2,PEBP1,CFDP1,RAB5A,EMC9,PIH1D1,EIF4B,DYNC1I2,PAIP1,RPS10,HMG20A,RPLP1,EED,AGR2,DRG1,AHSA1,RNF139,WWP2,IFI16,EIF3D,HNRNPF,G3BP1,KRAS,EMC8,SSRP1,RAD21,BZW2,PDHA1,EZH2,RPS23,SART3,RNF126,GPBP1L1,RPS11,E2F4,B3GNT2,LGR4,NDN,EIF4H,SRPK2,VIRMA,SMURF1,METAP2,CCNF,PSPC1,RPS3,RPS20,RPS12,GSK3A,EIF3G,UBE2H,MAPRE1,PPIG,ATP1A1,RUNX1,FBXW7,RPL4,CERS2,AATF,EIF4E,PML,SOD1,RPA3,PPM1G,BAP1,SQSTM1,ZCCHC17,RPA2,HEXIM1,KRT7,UBE2M,TFIP11,ATG16L1,CFTR,EIF3J,TOP1,RPS16,FZR1,MSMO1,RBM42,TFE3,USP3,ENY2,PPM1D,HDAC6,CSNK2A1,CD81,TGFBR2,SEM1,EIF4EBP2,EIF3E,DUSP21,MEPCE,ABCE1,CPNE2,DNAJC2,TFCP2,NUPR1,SRP72,TP53,YTHDF2,KBTBD4 |
| 2.411e-05 | -10.63 | ATP5ME (ATP synthase membrane subunit e) | protein interactions | 521 | 85 | 42 | 19454 | 5460 |
VDAC2,SSBP1,MOG,ATP5PD,PARL,ESR2,ATP5F1B,RPS16,ATP5F1A,TOMM40,CIDEB,MTG2,MYC,ATP5MG,SMAD2,NRP1,ILK,SMAD4,ATP5IF1,ATP5F1E,FOS,ATP5PF,SFXN1,CHMP2B,CERS6,CERS2,G3BP1,VDAC1,RER1,ATP5F1D,MAP1LC3B,SPG21,ATP5PB,SLC19A2,FAM13B,TIMMDC1,CAV2,CYC1,RPA2,SPRYD4,ATP5PO,NDUFS3 |
| 2.415e-05 | -10.63 | CASP3 (caspase 3) | protein interactions | 836 | 208 | 86 | 19454 | 5460 |
MDM2,PRKCQ,GLRX,STK3,EIF2S1,TOP1,SPTAN1,IL18,NEO1,ADD1,MCL1,RB1,LCMT1,DFFA,HCLS1,AIFM1,HSPB1,PPP3CA,SLC35A1,SNRNP70,BECN1,YWHAG,STK4,MAP3K14,CTNNB1,PLEKHO1,PSEN1,MDC1,PTGES3,ZBTB16,HSPE1,PLA2G4B,HSPD1,OTULIN,BIRC5,SRP72,NFE2L2,TRAF2,EEF2,TP53,ROCK1,TRAF1,KCNIP3,STAT1,GMDS,HEY2,CCNF,EIF2AK2,CTTN,DEDD,PTTG1,SP1,BAX,LSM14B,UBE2H,ARMT1,LMNB1,BRCA1,FBXW11,STK24,SOCS5,SAMHD1,GMNN,CASP4,BAG3,AR,AKT3,AKT1,EIF4E,MEF2A,TNFSF10,HMGB1,BIRC2,TRUB1,RPA3,PSEN2,EIF4B,MET,CRYAB,PAK2,PICALM,IDH3B,CDC42,CDKN1A,EIF3J,PIP5K1A |
| 2.429e-05 | -10.63 | positive regulation of protein modification process | biological process | GO:0031401 | 762 | 276 | 18204 | 5365 |
XRCC5,TBK1,FAM161A,PIAS1,DIRAS1,F2,CCL19,CLDN3,POMT2,ACVR1,TRAF6,RARRES2,STRADB,ADNP,PIH1D1,WBP1L,TESK1,ILK,DCUN1D3,CDKN1A,NDN,PML,ARL2BP,CHI3L1,PHF23,HCLS1,DCUN1D1,TNFRSF14,PSMD10,MAP2K6,HRAS,AGER,STK11,HDAC6,PRR5L,CAB39,FBXW7,NKX3-1,CD40,RALB,STUB1,FGF7,SYK,FGF16,TRIM6,LACRT,RPS3,BIRC2,PHB1,YES1,TFRC,TRAF2,CX3CR1,RAP1A,UBE2L3,ROCK2,MUL1,RAF1,CX3CL1,FGF17,TNF,ADIPOQ,DCUN1D5,DDRGK1,MAP3K11,FGF3,NBN,CAMK1,NTRK2,NTRK3,OSM,FAXDC2,BRMS1,GPNMB,CUL3,CDKN1B,RAP2A,IL3,EZH2,CHRNA7,VEGFA,SEMA7A,IL23A,FGF23,IL34,RBCK1,EGR1,IL15,EPO,TICAM1,NSMCE3,DLG4,LEP,SQSTM1,TLR4,APLNR,PIK3CG,PTPN11,HUWE1,PHB2,ANGPT1,RAP2C,GHR,ADORA1,SRC,FGF22,PTPN1,MIR26B,CSH1,IL18,RB1CC1,FGFR1,P2RY1,IL13,MIR34A,CAMP,LEPR,IL21,CACUL1,NTF4,IFNG,SPPL3,TAB2,TP53,TCIM,STK4,DIPK2A,CCNY,CRKL,DLG3,UBE2D1,UBE2N,CARTPT,DIRAS2,TGFBR2,IL2,SKP1,PAK2,MIR221,ARRDC3,CCND1,TOPORS,NDFIP1,KIT,SOX9,FAS,TOLLIP,ODAM,DERL1,FCGR1A,GSK3A,CRY1,MAP2K1,DVL2,CDK5RAP3,NRP1,KDM1A,FGF1,MMD,JAK2,PTEN,IL5,TANK,ADRB2,GREM1,TNFSF18,PROX1,ADTRP,TLR6,CCR7,IFNA13,SLCO3A1,GABARAP,IL1B,DYRK1A,TNFSF15,NOP53,AKT1,FAM107A,PTPN22,UBE2V2,RAP2B,UBE2V1,NCK1,CCND3,MT3,TXN,FGF10,GH1,OSBP,MAP2K3,PIK3R3,CHP1,TGFB2,PDCD10,SVIP,KRAS,IGF1,RPS2,PSEN1,TNIK,UBE2S,HBEGF,CD4,MIR21,MIR30B,IFNA2,LCP2,EHD4,CREBL2,NPTN,RGCC,IL4,PPP2R5A,HSPA5,HDAC3,EMP2,NOS1AP,MOB3C,IFNK,ATG7,PRKAG1,EFNA5,CD36,CD80,HSP90AB1,AGAP2,UCN,NMI,TAB1,MAVS,CLEC6A,IFNB1,CAV1,MAD2L2,SMYD3,VEGFC,FLOT1,PELI1,HSP90AA1,MAP3K12,CLIP3,PRNP,IL6ST,CSF2,HAX1,TPD52L1,RWDD3,IL12A,BCL10,HTR2A,PSRC1,MIF,PPP1R12A,DUSP19,UBB,NUPR1,CDC20,IFNA10,CD86,MMP9,FZR1,PPIA,TOM1L1,MOB3B,IL6,FERMT2,ERP29,RCHY1,UBE3A,IL12B,UBE2K,TLR3,EPHA4,CCL5,MAGEC2 |
| 2.446e-05 | -10.62 | FAM241A (family with sequence similarity 241 member A) | protein interactions | 132720 | 101 | 48 | 19454 | 5460 |
PGRMC1,ST7,LPAR1,RER1,TACR3,CLDND1,DAD1,TMX2,CD40,TSPAN15,VIPR1,RABAC1,RTN4,ATP1B3,NRP1,ATP5MC3,ATP1A1,REEP6,OST4,TMEM38B,PLP1,MOG,STUM,FZD4,RETREG3,RPN1,AQP3,KLHL26,CYB5B,TPBG,MACO1,TMT1B,TP53,APH1A,AHCYL1,FKBP8,MAN1A2,POR,FAM241B,ESYT1,TSPAN10,TMEM208,EMC6,ARL6IP5,OPRL1,TMEM170A,STT3A,CYB5A |
| 2.446e-05 | -10.62 | PRKCG (protein kinase C gamma) | protein interactions | 5582 | 101 | 48 | 19454 | 5460 |
TUBB4B,DDX39A,NRGN,RIGI,CYTH2,PRPS1,SLC25A5,HSPD1,PRPSAP1,PICK1,BAG2,TIAM1,YWHAB,HSPB1,YWHAG,CTNNB1,G6PD,HSP90AB1,AIFM1,GJA1,SDC2,PARD6A,PRKCA,ANXA7,SLC25A3,PCK2,CDC42,GABRA1,STXBP1,EIF4E,RANBP10,RGS2,DVL2,PEBP1,PRKCB,HSPA8,TRIM5,DNAJC10,IVNS1ABP,CCHCR1,HSP90AA1,EXOC5,FBXO7,DNAJC5,PRKCE,SMURF1,PNMA1,GSK3A |
| 2.452e-05 | -10.62 | ATP6V0A1 (ATPase H+ transporting V0 subunit a1) | protein interactions | 535 | 162 | 70 | 19454 | 5460 |
LGALS8,LAMTOR1,SCFD1,EPHA2,CSK,NONO,DNAJC5,SLC30A5,LGALS3,RHOJ,MGST3,APEX1,ATP6AP2,SRC,ESR2,ROCK1,LMBR1L,VAMP3,ZNF267,ATP5PO,RPA2,CSNK1G3,SLC25A3,ATP6V0E1,ATP6V1C1,BORCS6,FTH1,CDC42,RND2,STK38,ATP6V1G2,STAU1,RPS15,EMC1,ATP6V1G1,RPA3,SLC35F2,EMP3,TMEM185A,ESYT1,SLC2A1,ATP6V1D,PLPP4,LAMTOR2,RAB5C,TMEM199,BTF3L4,MRPL50,RHOH,TTC9C,VAMP7,PTPN1,RAC2,CD4,ATP6V1A,RNF128,PTRH2,VAMP2,EZH2,CTNNA2,GNAZ,TP53,MARCKSL1,GTF2E2,DNAJC25,RIGI,TFG,TOMM6,CYTH2,EMC2 |
| 2.459e-05 | -10.61 | MYCBP2 (MYC binding protein 2) | protein interactions | 23077 | 211 | 87 | 19454 | 5460 |
CCNF,GUCY1B1,NDP,UBE2L3,DYRK1A,VIRMA,SRPK2,RSPH1,CIAO1,LILRA3,CFL1,AR,PPP1CC,TXNIP,BAP1,SOD1,RPA3,SIRT7,CCDC65,KDM1A,FBXW7,AATF,ATG16L1,MYLIP,FAXC,RPA2,HECTD1,ARL6IP5,CGAS,SLAIN2,BAK1,CD81,TESK1,MAP4,IGFBP4,USP15,FAF1,SFXN1,LRRN4CL,METTL15,PHF21A,STAT2,BTG3,ESR2,MYC,LDHB,CUL3,SFN,GGH,YWHAZ,COP1,RPS5,OAZ1,NGRN,CRY1,UBE2D3,SERPINB6,STAU1,SKP1,ASB8,CSRNP1,HNRNPL,EGLN3,HSP90AB1,STK3,YWHAG,YWHAH,AGR2,TLR10,MED4,YWHAB,LSM14A,HNRNPA2B1,FHL3,VPS26B,PDIA6,UBE3A,SKA1,RBBP7,NUP42,SESN3,TOP3B,RAF1,LGR4,KIF2A,TUBB4B,HDAC11 |
| 2.460e-05 | -10.61 | RBBP7 (RB binding protein 7, chromatin remodeling factor) | protein interactions | 5931 | 478 | 175 | 19454 | 5460 |
PHF1,PSMA5,H3C1,ABCE1,RPL3,IDH1,MAP1B,HBP1,NUPR1,NKX3-2,ZMYM3,TP53,CDC5L,SPPL3,SHPRH,BRMS1L,GATAD1,USP15,CSNK2A1,GAPDH,HSPA5,KDM1A,RNF113A,BAP1,BANF1,UBE2M,HEXIM1,LUC7L3,ACACA,WRAP53,RPA2,CAPN1,MYG1,NR1I2,BUB3,ADRM1,TXNDC12,ING2,RPS3,UBN1,ZBTB38,UBE2H,CHRAC1,SMARCA5,RPL7A,MORF4L1,RPS4X,PSMA1,RUVBL1,RUVBL2,PDIA6,MTA2,SMARCB1,SOX2,RPS7,HMG20A,CCT7,DYNC1I2,SUMO2,TCP1,EED,ZHX1,CCDC71,SIN3A,DDRGK1,PFDN5,SAP18,UFL1,OXCT1,EEF1G,HDAC5,HSPA8,EP300,HIRA,NACC2,ADSS2,RPL27A,CBX5,PSMB6,ESR2,PSMD6,ZMYM2,PRMT5,PHF12,CCT2,PSMD1,RPL39,BTF3,PCCB,BRMS1,CPSF2,MYC,CREBBP,GFUS,SFN,LSM4,HUWE1,FN3KRP,CDK2AP2,THRAP3,HSPE1,HSD17B10,TCOF1,TOPORS,SAP30L,MAP2K3,ING1,MTA3,CCT5,PHF23,ZBTB2,DCK,RB1,H2AZ1,EPOP,CD9,SUV39H1,MBD3,GTF2I,NUCKS1,SMC4,FBXW7,RPA3,SIRT7,CDAN1,LMNA,METTL14,ATG16L1,RPS14,TPT1,EAF2,VIRMA,RPL13A,CCNF,TUBA1B,EZH1,RPL26,KPNA6,PPP1CC,AHCYL1,RAD21,ASF1A,SRSF7,ARGLU1,EZH2,NME1,ACTN4,SAP30,EGLN3,ARHGAP25,COPS2,RPL23,PSMD3,HMGA1,PSMC1,TGIF2LX,PSMA3,PSMB7,WDR77,ACTL6A,MAD2L2,PRDX2,RBBP4,MED17,SNRPD2,RAN,SP1,HSP90AA1,PFDN6,NLRP3,ILK,ARHGAP19,DCAF4,BRCA1,CUL3 |
| 2.467e-05 | -10.61 | RAD1 (RAD1 checkpoint DNA exonuclease) | protein interactions | 5810 | 52 | 29 | 19454 | 5460 |
TUBA1B,CSNK2B,PRMT5,RPS20,RFC5,COPS5,CSNK2A1,OGG1,POLB,BRCA1,DNAJC7,TOPBP1,RIT1,RFC4,CHCHD2,KRAS,ZBTB14,RFC3,CMAS,MSH6,RFC2,WDR77,FEN1,LBR,MAP1LC3B,HADH,GTF3C4,RPA2,RAD1 |
| 2.467e-05 | -10.61 | HELZ2 (helicase with zinc finger 2) | protein interactions | 85441 | 52 | 29 | 19454 | 5460 |
RPS3,PRR3,CGAS,RPS10,RPS16,ESR2,VIRMA,MYC,IFI16,DCAF4,SIRT7,HUWE1,G3BP1,SLC31A1,FTL,RIGI,BCL6,FBP1,ATG16L1,PABPC5,RAF1,TOP3B,RBMS2,APOBEC3D,ISG15,PPARA,SOX2,PPARG,EZH2 |
| 2.471e-05 | -10.61 | CCR10 (C-C motif chemokine receptor 10) | protein interactions | 2826 | 11 | 10 | 19454 | 5460 |
CCL28,CCL27,CXCL13,CCL2,ARPC3,CCL25,PRRC2A,RIGI,CCR7,CCL19 |
| 2.513e-05 | -10.59 | BANF1 (BAF nuclear assembly factor 1) | protein interactions | 8815 | 185 | 78 | 19454 | 5460 |
MTA2,NUPR1,SSBP3,FURIN,APTX,CBX3,NGB,CHMP4C,DNAJC2,SOX2,CD2BP2,TOP3B,MDC1,SSRP1,PAEP,H3C1,RBBP7,G3BP1,KRAS,TNF,EPHA4,VRK1,VDAC1,ATP5PF,HNRNPD,CBL,RB1CC1,BRD3,BCL7C,HDAC6,DDRGK1,DPP4,HMGA1,DPY30,TMPO,CNTROB,CDK9,NUP35,FZR1,TOP1,SNRPD3,H2AZ1,HEXIM1,MET,LUC7L3,LMNA,METTL14,COMMD3,ZNF428,ACTL6A,ATG16L1,BET1,UFL1,TRA2B,NUCKS1,RNF113A,RAB9A,INPPL1,SOD1,BAP1,BANF1,NTRK3,SP1,UBE2H,H1-1,LMNB1,BTF3,SMARCE1,USP14,PPP1CC,TUFM,MYC,CUL3,HNRNPC,SUB1,RPL10,APEX1,RBBP4 |
| 2.542e-05 | -10.58 | EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3) | protein interactions | 9451 | 148 | 65 | 19454 | 5460 |
TMPO,LMAN1,ASIC1,FMOD,DNAJC1,EIF2S1,RAC2,HSD17B11,GJA1,RAB35,PTPN1,ESYT1,RHOG,IKBKB,COPS5,DLK2,SLC25A46,FKBP8,TMED7,TUSC3,RAB3B,TMT1A,ILF2,NFE2L2,SFTPC,PTRH2,RPN1,STIM1,DNAJC25,B4GAT1,SEC63,VIRMA,TRAF1,SEC61B,RMDN3,UBE2H,HSP90AA1,HFE,FAS,BFAR,GLT8D2,PCDHB1,SCN3B,OST4,AKT1,HSPA5,BCL6,STX7,DAD1,PXMP2,RAB9A,DERL1,RAB5A,DNAJC3,RHBDL3,OGFOD3,CHRNB2,HSP90B1,SSR1,ST7,SEC62,CDC42,TMEM106A,OTULINL,RND2 |
| 2.547e-05 | -10.58 | RPS29 (ribosomal protein S29) | protein interactions | 6235 | 165 | 71 | 19454 | 5460 |
WWP2,HDAC6,DDRGK1,AGR2,SNRNP70,RPS2,CBL,FOLR1,RPL9,RPL8,RPS10,FZR1,RPS16,RPL7,PRNP,RBM42,RPSA,DNAJC25,RPS7,RPS11,RPS23,ABCE1,RPS24,KRAS,EPHA4,TNF,VRK1,RPL28,RPS13,RPS4X,MEPCE,MYC,CIAO1,RPL26,RPS17,PPP1CC,BAG3,SPOP,LMNB1,RPS5,NTRK3,RPS26,MAPRE1,DNAJC19,UBE2H,FAU,RPS3,RPS12,RPS20,RPS9,EIF4A2,UMPS,DYNLT3,RPL19,RPL10,ESR2,RPS14,RPL26L1,HEXIM1,KLF4,RPL27,BAP1,PYM1,GLIPR1,RPS28,SYVN1,EXOSC4,EIF1B,RPS15,UFL1,HMGB1 |
| 2.547e-05 | -10.58 | MRM3 (mitochondrial rRNA methyltransferase 3) | protein interactions | 55178 | 165 | 71 | 19454 | 5460 |
MRPL10,USP39,RPLP0,MTRES1,JAGN1,NGRN,ATPAF2,GFM1,LCN1,EP300,UFL1,MRPS7,MTG2,MYC,AUH,CUL2,NUDT1,PMPCA,FBXO7,TUFM,RC3H2,MAPRE1,PSPC1,MRPL53,TACO1,MTG1,PRKRA,MRPL13,CPT2,LAMTOR3,PARL,ESR2,RPL10,MARCKSL1,RAF1,TBK1,MRPL11,MRPL47,UBIAD1,AURKAIP1,METTL15,PDHA1,NDUFS6,SMNDC1,NUPR1,HSPD1,RPL23A,HINT2,FHL3,GAD2,COX8A,KRAS,TNF,FASTKD5,GALNT2,IMMP2L,MTRF1,GRSF1,IFI16,DDRGK1,MRPL18,SNRNP70,MRPS26,BTN2A2,SSBP1,GATD3,CAND1,RPS16,MRPL50,MALSU1,AIG1 |
| 2.547e-05 | -10.58 | MUC1 (mucin 1, cell surface associated) | protein interactions | 4582 | 165 | 71 | 19454 | 5460 |
NINJ1,EMP3,TMEM243,ENTPD3,CMTM7,WWP1,GALNT1,JUP,SMCO4,PPARG,CDKN1A,GALNT4,PLP2,CCDC167,TRAM1L1,SEC22B,EDDM3B,NUP62,SRC,ESR2,TECR,CD47,THBD,TMEM229B,PLP1,SLC35E4,BAX,PLN,HSP90AA1,OSGEP,SLC35B4,CSGALNACT2,VAMP5,GALNT2,PLPP6,CTNND1,ADIPOQ,CLDN6,TMEM147,GALNT12,ERG28,UNC50,CYB5B,SFTPC,CTSA,AQP3,TMEM59L,EZH2,VAMP2,PPIF,JUN,NEU1,TP53,SELENOK,INSIG2,TMEM97,CXCL9,ANKRD46,MFSD5,ACTA2,TMEM14A,BTN2A2,AQP2,C2CD2L,TMEM11,SCAMP5,IKBKB,CTNNB1,EMC6,SLC38A7,TMEM199 |
| 2.551e-05 | -10.58 | LHFPL4 (LHFPL tetraspan subfamily member 4) | protein interactions | 375323 | 31 | 20 | 19454 | 5460 |
YTHDF1,GTF2I,ATP5F1B,SPPL3,RABIF,PRPS1,ACP2,FKRP,ACOX1,FAM91A1,TEX264,CBFB,LCP1,GPX4,ATP5IF1,STOM,ATP1A3,GAMT,RABL3,HSDL2 |
| 2.570e-05 | -10.57 | THRAP3 (thyroid hormone receptor associated protein 3) | protein interactions | 9967 | 407 | 152 | 19454 | 5460 |
HMGB1,FBXW7,AATF,RPA3,PPM1G,RNF113A,CLK1,WWP1,METTL14,LMNA,RPA2,NUDT12,HEXIM1,SF3A1,CDK7,CDC42,NEK2,PRKCE,MAGOHB,SRPK2,DEK,SMURF1,EIF4A3,CCNF,SF3B6,ALB,MACROH2A1,PHAX,CSNK2B,GSK3A,IVNS1ABP,RC3H2,UBE2H,CASC3,PPIG,PPP1CC,AR,CAMKV,MDC1,SMN1,MEPCE,TCOF1,SNIP1,MAP1B,DHX9,IK,CDK8,NUPR1,TP53,FBP1,EEF1A1,APOBEC3D,CD2BP2,THOC1,TOP1,CAND1,CAV1,ZBTB2,RBM42,ALYREF,H2AZ1,TES,ARL4D,CD9,SNRNP70,CDK12,H2AC14,API5,CSNK2A1,EEF1G,STAU1,UFL1,ASB3,SAP18,UPF3B,NKAPD1,DDX39B,PYM1,SNRPA,EP300,RAB5A,DDX5,HSPA8,SF3B1,ADSS2,LXN,ZC3H14,ALKBH3,ELK4,RBBP4,MATR3,CAVIN2,SNRPB2,APEX1,ERH,DLST,SNRPD2,LMNB1,FBXW11,CDKL2,H1-1,HNRNPC,MYC,HNF1B,SNRPB,BTF3,RNF40,VDAC1,CHCHD2,RBBP7,KRAS,SSRP1,AHCYL1,UBE2A,SRSF4,TRIP4,SRSF7,SRSF8,EWSR1,HDAC11,PDHA1,EZH2,GLE1,TUBB4B,SKA3,SART3,SUPT5H,VDR,RAF1,MAX,TNPO2,LGR4,SOX2,ISG15,NCSTN,SNRPA1,HNRNPL,SRSF1,COPS2,DROSHA,DDX23,MAGOH,AHSA1,MED4,WWP2,HMGA1,CTNNB1,DDRGK1,NT5C2,TRA2A,XPO1,YWHAG |
| 2.578e-05 | -10.57 | GLG1 (golgi glycoprotein 1) | protein interactions | 2734 | 112 | 52 | 19454 | 5460 |
RNF128,NRSN1,FBXO32,FZR1,EIF2B5,GOLPH3L,ETFRF1,TSEN34,NFKB1,RPL6,OSBPL8,AGR2,SLC2A8,UST,RIGI,CAMKV,DNAJC25,TULP3,STK16,AQP3,DKK3,SEC61B,BAD,NFKBIB,NFKBIA,ESR2,VIRMA,TAX1BP1,MYC,CSK,NRP1,SDF2L1,PSMD14,CGRRF1,HSPA8,HADHA,SQSTM1,RAB5A,MTDH,RPA3,TMEM106B,ITM2B,GTF2I,UFL1,HSCB,NEK7,ATG16L1,GINM1,SYK,FAM8A1,PIH1D1,RPA2 |
| 2.578e-05 | -10.57 | RECQL5 (RecQ like helicase 5) | protein interactions | 9400 | 112 | 52 | 19454 | 5460 |
SNRNP40,MED17,POLR2B,ESR2,SRPK2,CREB1,CCNF,FBLN5,ZNF330,POLR2F,MED10,BRCA1,MYC,LMO2,TIMP1,PITHD1,EEF1G,RPA3,NLE1,NBN,KIN,RPRD1B,WWP1,STAMBP,TOP1,POLR2I,RPRD1A,POLR2L,LDLR,MED21,DDX23,FOSL2,MED27,MED4,WWP2,H3C1,RIGI,MDC1,EIF2D,RPL31,PCNA,FAM168A,EZH2,DDX42,DXO,POLR2D,POLR2C,POLR2G,TOP3B,SUPT5H,TP53,RPAP2 |
| 2.580e-05 | -10.57 | SLC22A4 (solute carrier family 22 member 4) | protein interactions | 6583 | 188 | 79 | 19454 | 5460 |
ARL10,HRAS,RAC2,MFSD5,DERL2,RHOH,SPPL3,TLCD4,CAV1,SLC25A17,DHRS7,SLC25A46,ORMDL3,TMEM11,DOLK,RHOG,FITM2,NDUFB8,SMDT1,ATP2B4,TRAPPC1,TMEM87A,SLC25A23,B4GALT7,COA1,LPCAT3,EIF2D,SLC6A8,AGPAT5,CYB5R1,YIPF3,PTRH2,NHERF1,STIM1,SLC25A24,CRELD1,DHRS3,NDUFA12,SMAP2,ALG2,SELENOT,PTPMT1,GPR89A,ADGRL3,SERINC1,CYBC1,ABHD14B,DHRS13,TAMM41,PARL,UQCRQ,SLC25A42,SLC30A5,RHOB,TAFAZZIN,DNAJC19,VMP1,TSPAN15,ORMDL1,RHOU,TMEM126B,RTN4,SLC35F2,HACD1,SLC25A51,TMEM177,SLC5A6,CERS6,PXMP2,STX7,SLC19A2,HACD2,RND2,CDC42,CTDSP1,TMEM115,LMBRD2,PIGW,CSNK1G3 |
| 2.580e-05 | -10.57 | PDLIM5 (PDZ and LIM domain 5) | protein interactions | 10611 | 188 | 79 | 19454 | 5460 |
BRCA1,BICD2,CALU,ZMPSTE24,UBE2H,ILK,ZBTB38,PSMA4,RAB11A,CUL3,EMILIN1,ST13,DNAJC8,HSD17B1,ACTB,TSN,PRKCE,ADRM1,TMOD3,NDN,DYRK1A,ESR2,CDPF1,EIF4A3,MIDEAS,STUB1,CCNF,MAP2K1,LMNA,RPA2,SPTBN1,CFTR,NUCKS1,STAU1,HSCB,COIL,BAP1,SQSTM1,PRKCB,HSPA8,YWHAB,HSPB1,MED4,SSX2IP,CBL,KARS1,CTNNB1,XPO1,COPS5,HDAC6,KCTD10,HNRNPL,CEP19,CACYBP,FBXO32,SRP14,SMAD3,SIN3A,TES,METTL6,DSTN,CBX3,RAD23B,TXNRD1,KBTBD4,TPD52,RAF1,ANP32A,TULP3,HNRNPK,G3BP1,CAMK2G,PDE12,CAPZA1,CBLL1,ZYX,RAB1A,BAG2,ZC3H7A |
| 2.602e-05 | -10.56 | PNO1 (partner of NOB1 homolog) | protein interactions | 56902 | 123 | 56 | 19454 | 5460 |
RB1,EED,RXRG,EGLN3,NCBP2,CGAS,NOB1,RPS16,CAND1,FZR1,CTNNB1,DDRGK1,HNRNPA1,XPO1,STOML2,IFI16,BRD3,RPS24,PICK1,HNRNPA2B1,RPS13,RPS7,SOX2,MAP1LC3B,RPSA,SUPT5H,COMTD1,CSNK1E,RPS23,DCUN1D5,HBP1,RPS11,RPS9,RPS20,RPS12,CCNF,RPS3,FAU,LMBR1L,PSPC1,ESR2,RPL10,FRZB,MYC,UBE2H,RPS26,RPS5,EP300,RPA3,PYM1,G3BP2,NPM3,WDR3,TMOD1,GSTP1,RPA2 |
| 2.602e-05 | -10.56 | UBA5 (ubiquitin like modifier activating enzyme 5) | protein interactions | 79876 | 123 | 56 | 19454 | 5460 |
PGK1,EP300,RPS28,MRPL17,UBE2K,NSFL1C,PRDX3,GABARAPL2,LAP3,MREG,SH3GLB2,PRKCA,IPP,HSP90B1,GANAB,CYTH1,PSPC1,PNMA1,VAMP3,ACOX1,UBE2L3,APEX1,ESR2,USP5,ATG101,CRMP1,THTPA,NAE1,SFXN1,CCT8,RNF20,KRAS,UFM1,HSPE1,ETFA,HADH,DDX39A,CARTPT,PGM1,NAA15,SNAP29,APEH,JPT2,ADAMTS1,LDLR,ALYREF,BOLL,RPL32,NCBP2,CDC5L,RPS16,EIF2S1,XPO1,ATP6V1D,GSTO1,FKBP4 |
| 2.602e-05 | -10.56 | ERO1A (endoplasmic reticulum oxidoreductase 1 alpha) | protein interactions | 30001 | 123 | 56 | 19454 | 5460 |
HSPA5,APPBP2,HSPA8,HNRNPH2,DDX5,PMAIP1,NUP50,RHOU,DNAJC3,RPA3,TMEM106B,PDIA2,PAK2,RPA2,PSMB7,P3H1,CAPN1,TANK,MAT2B,CTSB,MSN,SEC61B,CCNF,AP2A1,CALU,UBE2H,LACRT,YWHAZ,DNAJC10,TUFM,NIBAN2,MAT2A,RIGI,DNAJC30,ERO1A,AKT2,HNRNPA2B1,PPME1,TFRC,GPX7,PLS3,EZH2,BPIFB1,H2AX,MAP1LC3B,TRAF2,G6PD,HSP90AB1,PRNP,TNIK,AGR2,COPS5,PDIA3,DPP4,GRSF1,FAM20C |
| 2.602e-05 | -10.56 | ETF1 (eukaryotic translation termination factor 1) | protein interactions | 2107 | 123 | 56 | 19454 | 5460 |
EIF2S2,ALB,NDN,TSN,FBXO22,RHOJ,ESR2,NCKAP1,MYC,CYP1A1,ATG3,PDCD4,NTRK3,RIT1,DNAJB6,RPA3,RHOU,HSPA8,PRKCB,RNF5,BCL6,ACTL6A,RND2,SNRNP27,CDC42,RPA2,METTL14,CD274,CORO1C,RAC2,RPL35A,EIF2S1,RHOH,MBD5,SLC38A7,VPS26A,ATG7,XPO1,COPS5,AGR2,PABPC1,DNAJB4,ABCE1,UBE3A,MRPS11,PSMA1,G3BP1,KRAS,PTGES3,RNF26,SAR1B,GTF2E2,RPS7,RND3,OTULIN,RHOBTB1 |
| 2.613e-05 | -10.55 | regulation of interleukin-1 beta production | biological process | GO:0032651 | 110 | 53 | 18204 | 5365 |
IL6,SERPINB1,CLEC7A,GSTP1,CX3CR1,MIR920,TNFAIP3,HSPB1,MIR877,PYDC2,TMEM106A,TNF,IGF1,FOXP1,IFNG,MIR144,MIR101-1,CX3CL1,SMAD3,CCR7,TLR6,MIR98,TLR4,AGER,MIR361,PYCARD,NLRP1,CCL3,MIR132,CD36,MIR195,ARG2,NLRP2,MIR488,TYROBP,JAK2,CPTP,RAD21,MIR708,EGR1,ACP5,PML,MIR204,CCL19,IFI16,LILRA2,TLR8,LILRB4,GHRL,MIR181D,MIR206,NLRP3,MYD88 |
| 2.616e-05 | -10.55 | cellular component assembly | biological process | GO:0022607 | 2472 | 815 | 18204 | 5365 |
FITM2,ZNF207,PEG10,G3BP1,TDRD7,CDC20,SLU7,RPL23A,SSBP1,SNIP1,CDK1,CLDN6,INPP5K,KCNJ2,PWP2,SNAP25,UQCC6,WDR45,HSP90AA1,MED21,EIF2S2,NDUFA12,ARPC2,TNKS,CAV1,PFDN6,MCOLN1,ADGRL3,CFAP161,ACHE,CAV3,KCTD17,MSRB1,CNTROB,RAB1A,HSP90AB1,TMEM70,NAA60,ZYX,ALKBH5,IFT57,TAF2,IFIH1,GABRB2,ATG9A,GJC1,RPS27L,MTM1,PSEN1,CLDN1,UBE2I,SNRPG,GTF2H5,STBD1,KLHL12,SNRPD3,REEP3,SRPK2,NCK1,CLDN9,SHOC1,TWNK,EIF2D,EIF3J,WASL,RAP2B,NDUFA1,TRIM37,WASF3,KCTD15,WDCP,PROX1,CREBBP,JCHAIN,CDH13,TPPP,VPS4B,FARSA,MACROH2A1,TMOD2,CAV2,PLS3,COIL,H2BC11,NLRP6,NCKAP1,TTC8,HPS6,CCT2,RAP1B,SNRPE,UBN1,SNRPA1,MAP1LC3A,NAP1L5,CTNNA1,CIRBP,CCL21,CFAP298,GPX4,NAP1L3,PICALM,NDUFA2,BCS1L,TAF7,LPAR1,SRPRB,ATG101,VPS4A,COX10,ITGA6,MITF,EMP3,RRP7A,CHMP1B,NDUFAB1,RAC2,TBCE,FGFR1,SRSF1,FKBP10,LRRC8A,UGDH,DNAAF10,POLE3,CNOT7,MKKS,CHCHD4,SRP54,RAB32,CEP41,CAPG,H2BC14,RPS5,COA1,YTHDF2,TMEM237,CALHM3,STX12,JUP,LYRM2,GABARAPL2,RAP2A,TMOD1,CLSTN3,RACGAP1,RAF1,ATPAF2,RPS3,TRIM6,RAB11A,CNTNAP1,H1-1,ATL1,TRAF2,TRAF1,NTNG2,H2BC1,VPS28,EMC6,ZDHHC8,KCTD11,MAPRE2,GABRB3,YTHDF1,PYCARD,BRIX1,STXBP6,PREB,S100A10,BCCIP,ATG3,CIDEB,USP16,HSP90B1,PPAN,RPF2,DNAL1,VAMP2,KCNA3,INPPL1,PSMD10,CTTN,PSMG3,H2AX,ASIC2,LDB1,H1-6,PRKCA,NEFL,TMEM126A,CDH11,RPS28,BOLA2B,EXOC5,PPIH,LRRC4,SNRPB2,STOML2,KCNF1,CFL2,PCDH17,RTKN,COPS7A,NDUFB6,MRPS7,AP1S2,HSPD1,HAS3,KCNA2,OTX2,TRAF7,MAP4,FLOT1,SNAP91,LUC7L3,GNMT,WSB1,PALS2,VAV2,AQP2,MLH3,MED29,KHDC4,RPS23,NOA1,CLDN11,CHMP2A,NDUFS3,H3C1,GJA10,RPLP0,SRSF10,TIA1,UBE2B,MYBL2,SMURF1,B9D2,ILDR1,EMP2,RTN4,NOPCHAP1,DNM2,FMC1,SEPTIN6,TRAPPC1,COX7A1,CD9,POC1B,AQP4,VAMP1,HSD17B10,BOK,WDR77,CATIP,EIF3D,AP1M1,PDCD10,UQCC3,DR1,GEMIN8,RPSA,CYFIP2,COPS7B,IFT25,SLC1A2,CTNNB1,NOP53,MIOS,GMNN,AIF1L,SDHAF2,RSPH1,GABARAP,PRMT5,LSM4,STX7,CAND1,STXBP1,JAK2,PTEN,MED31,MIS12,SSX2IP,CD34,ACACA,TUBA1A,BAD,UGCG,FGD2,ASF1A,EIF3G,GRIA1,TMEM126B,ENKD1,CRKL,ATG4C,RRN3,RIC3,STK26,NUP153,SNX10,MED17,DYNLL1,BIRC5,TOM1,MEF2A,PRKRA,TESK2,PDCL,RAB8B,C1QL3,ANGPT1,CLDN14,PPID,SMARCA5,SRC,SLC25A46,CALY,MTMR2,PTGES3,EXT1,SQSTM1,SF3B6,TM9SF4,SNRPB,KRIT1,EPS8,ISCA2,NDC80,SMARCB1,MECP2,SIGMAR1,SLITRK1,COX17,MPV17L2,LPXN,CELF6,EDC3,TMEM199,TRAPPC4,CLDN8,ACTR2,NBN,EIF3K,AP3S2,PET117,GPAA1,CRTC2,EIF1AX,KCNJ10,ISCU,CDH7,ATG16L1,ATG4A,CDH8,CLTRN,RAP1A,RILPL2,TAF9,ESAM,COL1A2,MED30,MACROH2A2,TMIGD1,COX19,CLU,KCNG3,FCHO2,NDUFA5,CFAP97D1,SRPRA,PML,SNRPD2,CBR4,DISC1,PSPC1,FGF13,ALOX5AP,KCTD16,UBXN2B,KCNJ8,SSNA1,EIF2S1,NDUFB5,HP1BP3,NLGN2,TRAF6,PLN,NEK2,CD2AP,NINJ1,SYCE3,RAB19,TXNL4A,IL2RB,RPS14,DDX42,KCNB1,ADD2,KCNC1,SPEF1,NUPR1,CRYAB,LIMD2,AGO1,CDC42,FLCN,FERMT2,CLDN22,IFT172,PSMG4,MAP1LC3B,SHPRH,BCL10,MIF,NDUFS8,STK3,C1QL2,SRSF12,TSSC4,ATP6V1D,HEY2,NDUFB7,UNC119B,TLCD1,RFX4,CLDN24,THG1L,RUVBL2,AP2M1,SEPTIN7,H1-10,SWAP70,NPTN,NDUFC2,H2BC9,IFT22,OPHN1,RPL10L,FXN,CBLN2,GTF2B,LSM2,FBLN5,GJB1,RAB29,GABRG2,ADD1,GJB2,PKP4,NAPG,DHX9,RAB1B,VAMP8,COL3A1,CHRAC1,GAS8,ZNHIT6,ADRB2,C9orf72,CFAP20,SLC31A1,MAT2A,SF3A1,PRPF19,RABL2B,VIPAS39,WDR11,HGS,ACTL9,CFAP61,SART3,SOX9,BAG3,GHRL,VTA1,DLG1,UBXN10,SF3B5,RAB13,BANF1,CBLN1,NAPA,LRRC8C,FMOD,DICER1,SPATA6,TRAPPC3,BECN1,SLC7A9,TP53,CIAO1,VCPIP1,STK4,KCTD12,MDM2,DDX23,SDCBP,GABRA1,EHD1,OCEL1,SOD2,NEK7,KIF3B,TUBG1,RAP2C,CIAO3,LARGE1,ZNHIT3,GEMIN7,DLG4,USP39,RPS15,ARF4,RBMX2,PIP4P1,HOMER1,CEP70,SDHAF4,GPM6A,GABRA2,SAMM50,DET1,CDC123,CFAP91,ATAT1,B2M,GABARAPL1,CHMP5,COA5,MAPRE1,PPP2R1A,DDX46,CD3G,TLCD2,CD247,CHMP4C,SF3B1,NDUFAF2,NGRN,CAPZA1,CX3CL1,HAUS2,SHMT1,ACTB,SLAIN2,CSRP1,MID1IP1,RUVBL1,PDIA3,OIP5,TRAPPC14,TESPA1,TEX12,CDK5,PHACTR1,NSFL1C,HFE,CLDN4,PFDN5,CXCL12,RANGRF,IL1RAP,MZB1,GTF2A2,MYO1B,MOBP,FITM1,EMILIN1,MED11,RBM5,TSPYL4,LSM14A,MED4,LSM3,WDR44,SDHAF1,LRRC8D,CD2BP2,TNFAIP1,PRPF18,BOLA1,TAFAZZIN,TRAPPC6A,TMEM107,RPL6,EID2,CASP4,BOLA3,CNTN1,TPPP3,SNRPD1,KCTD9,NLRP3,H2AB1,COA4,GJA1,RP2,CSNK2B,CTSD,H1-5,TIFA,AIF1,CLDN3,ARF6,ALDH1A3,DDX1,UBE2K,G3BP2,BBS5,GPM6B,IMMP2L,RAB23,MACIR,CHMP1A,DDX39B,CETN2,CEP19,ASPM,HAPLN2,TP53INP1,ATXN10,SCLT1,FAM149B1,SMN1,SLX1A,SNAP29,E2F4,SF3B4,PRNP,CRYZ,SAR1B,SSBP3,CCDC65,SMYD3,TPPP2,GTF2A1,MNS1,TP53INP2,MED27,TAPBP,OTUD6B,CHMP2B,RPL10,FHOD3,HDAC3,ATG7,UBE2S,TNIK,LPCAT3,OCRL,SLC39A9,EHD4,AQP11,NACC2,NSG1,CALR,CIBAR1,MAP1B,NUDCD3,RBBP4,AIFM1,KCND2,CLP1,WNT7A,FAM107A,ITGB5,TAPBPL,FKRP,GPC1,ITGA2,B9D1,PRND,CFAP73,PLA2G5,NRP1,RPGRIP1L,TSG101,TAF11,KCNS1,PIP5K1A,TFG,ATF1,LCP1,KRT8,CCDC69,FLRT3,ANP32B,KIT,FAS,NUBP2,KIF2A,REEP4,AR,PAK2,HIRA,PSMG2,HIGD1C,NUP107,TNNT2,FIG4,NLGN1,NDUFAF3,NDUFS2,COX20,TAF10,TIAM1,TCAP,PAFAH1B1,IFT52,NLE1,GNPAT,ADRM1,P2RY12,CENPW,ROCK1,UQCC2,POMP,WRAP53,H2BC17,NDE1,NDUFB10,RB1CC1,NDUFAF6,H1-3,HSD17B8,PMP22,THY1,TRAPPC2L,COX14,NECTIN2,ARHGEF6,RRM1,EIF3E,AP2S1,NDUFB4,TMEM170A,HIGD2A,CEP85,SAMHD1,CAPZA2,YWHAZ,PRKACB,TERB2,KCND3,BSCL2,SSRP1,CLDN12,CUL3,WDR19,PCDHB13,GORASP2,NDUFB8,STX17,NDUFAF4,TIMM21,TCP1,COX16,WEE2,KCTD10,RS1,SLC2A1,UBAP1,SPTBN1,MRM2,RAB33B,RAB33A,MED23,TMOD3,ASIC1,VMP1,MED9,TRIM32,RAB14,CD40,MED10,GK2,NLRP1,MED22,HSCB,HDAC6,KCTD3,POLDIP2,TUBB,CBLN4,NUP62,EHD3,ARL6,EIF5B,CLXN,GLRX5,GCFC2,NHERF1,CCDC42,TMEM231,PIH1D1,DRD1,LRRC61,ATP5F1D,SPMIP6,TACO1,PRPF31,FKBP4,CENPP,TBCEL,TLR2,SNAP23,NPTX1,ACOT13,XRCC5,PIAS1,FAM161A,VAMP3,NTN4 |
| 2.624e-05 | -10.55 | Sm | interpro domains | IPR047575 | 28 | 19 | 18521 | 5414 |
SNRPD3,EDC3,LSM6,LSM12,LSM10,SNRPG,LSM5,LSM14B,LSM14A,LSM4,SNRPD2,SNRPD1,LSM8,SNRPN,LSM3,LSM2,SNRPB,SNRPE,GEMIN7 |
| 2.631e-05 | -10.55 | BLOC1S6 (biogenesis of lysosomal organelles complex 1 subunit 6) | protein interactions | 26258 | 80 | 40 | 19454 | 5460 |
RINT1,CORO6,SKA1,BLOC1S2,STX18,SMN1,RIGI,VAMP8,STX11,TBK1,NUP62,BLOC1S3,SNAPIN,BORCS5,AGGF1,PTP4A2,CDK5R1,STX12,LURAP1,OLFM2,NDN,PLEKHF2,CCR2,HSBP1,BORCS7,EPS8,RAB5C,NDC80,SYCE3,TPM3,NTAQ1,INSYN1,CCDC22,BLOC1S5,MED21,LAMTOR1,BCAS4,STX1A,CCHCR1,EXOC8 |
| 2.637e-05 | -10.54 | focal adhesion | cellular component | GO:0005925 | 427 | 163 | 19108 | 5553 |
SDCBP,CD151,RHOU,PIP5K1A,MME,RPS9,NME2,YWHAZ,TADA1,RHOG,PPP1R12A,MAPRE2,PPIB,CORO1C,ARL14EP,FHL3,CFL1,DPP4,RPS4X,CD99L2,LAP3,PPIA,SLC6A4,RPL37A,ATAT1,DCTN4,AKAP12,PTK7,NCSTN,CD46,HSPA5,TGFB1I1,PPP1CB,CTNNA1,ALCAM,ADD1,HSPB1,RPS15,CD9,HACD3,RPL23,RPS3,KRAS,PPP1CC,RRAS2,THY1,FLRT2,TRIM15,RPS13,CBL,RHOB,CD59,CASK,MSN,CAPN1,CAV3,MMP14,LAMTOR3,JUP,NRP1,CAPN2,MDC1,MAP2K1,CAV1,RPL18,RPS2,RPLP0,YES1,ACTN4,CDC42,RPL4,CALR,RPS14,PABPC1,REXO2,CTTN,RPL10A,NECTIN2,RPL7A,HSP90B1,ZYX,RPLP1,ILK,PPFIBP1,CHP1,RPL19,ITGB5,HNRNPK,RPL9,YWHAG,RPS29,CTNNB1,GIT2,RPS11,SNAP23,GJA1,RPL31,LIMS2,CAV2,DAG1,RALA,ARF1,RPL27,FERMT2,TM4SF20,HSPA8,RND3,ITGA2,NCKAP1,G3BP1,FLRT3,YWHAB,PIK3R2,JAK2,L1CAM,RPS5,MAPRE1,SRC,LASP1,B2M,ICAM1,GDI2,RAC2,FAM107A,RPLP2,CSRP1,RPL7,CD81,HMGA1,PDIA3,RPS17,RPL13A,EHD3,EPHA2,RPS10,AIF1L,DNM2,RPL6,ITGAV,RPL8,TES,SHC1,ARPC3,SDC4,RPS7,FLOT1,JAK1,IRF2,CNN3,CDH13,ACTR2,ACTB,RPL3,STX16,LCP1,RPL12,RPS16,ARF6,RPL22,LPXN,ITGB8,ARPC2,ITGA6 |
| 2.639e-05 | -10.54 | DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) | protein interactions | 8445 | 168 | 72 | 19454 | 5460 |
RPLP0,SLC25A3,WTAP,SSBP2,RPL27A,NDE1,NOTCH2,SUMO1,NF2,PDHB,RPL4,FBXW7,HMGB1,G3BP2,CXXC1,FTL,HSPA5,HSPA8,TERT,DDX5,EIF3G,KIF3C,EPHA2,HSP90AA1,COX6B1,RPL7A,CFAP20,MAGOHB,NR1I2,SRPK2,CPSF1,CCSER2,DLST,UBE2I,CAPZA2,PNMA2,ZRANB2,TAF2,RNF8,RPL18,TBK1,TP53,YTHDF2,DDX39A,AKAP12,MEPCE,UBE2D1,DCAF5,DDX1,RB1CC1,RPS2,MAGOH,MOV10,KXD1,MAPK4,SAV1,STK4,TRA2A,SIAH2,RPS16,KIF3B,CCAR2,EIF2B5,RPL7,MIF,NKAP,MDM2,SRSF10,NCBP2,MRPL24,FUBP3,WDR82 |
| 2.649e-05 | -10.54 | RHOF (ras homolog family member F, filopodia associated) | protein interactions | 54509 | 671 | 236 | 19454 | 5460 |
NEDD8,AKAP12,CSE1L,SRPRB,SLC6A8,PALM2AKAP2,SLC16A1,ABCE1,EXOC3,TFRC,CCM2,BMPR2,SNAP29,ARHGAP12,ARL6IP5,CAND1,SPPL3,FCHO2,LMAN1,STX6,SLC38A2,TMPO,STT3A,ITGA6,FLRT2,RAP1B,SLC39A10,ADD1,SLITRK5,KPNA1,AGPAT1,FTSJ1,CLDND1,RAB9A,VPS4B,SSR1,GIT2,LEMD3,SPTBN1,CDC42,KLRD1,RALA,ROCK1,UQCRC2,NECTIN2,LIG3,QSER1,STX10,ATP1B3,DNAJC10,ATP1A1,SLC25A1,RAB2A,PTPN11,ARHGAP21,CFL2,SLC6A6,SLC20A2,ROCK2,VAMP8,PRPS1,TOP2B,EFNB1,CDK5,SEC11A,UCK2,TOP3B,TUBA1A,TTC9C,ASIC1,STX5,ARHGAP5,DRG2,TOX,ANKRD50,DDX50,RAB5C,WWP2,PTDSS1,PPFIBP1,XPO1,OLR1,CTNNB1,TBC1D5,EMC1,ITGAV,ABCC5,PACSIN3,PAK2,MAP2K1,USP6NL,ESR2,ATP6AP2,NCKAP1,KTI12,MTG1,RRAS2,FAM83B,SLCO3A1,SPCS3,LAMTOR1,SLC38A1,SLC1A3,STX16,RPS13,ADD2,RAB1A,EHD4,NSDHL,DLG1,SFXN1,HAPSTR1,SNAP23,EMC2,ZDHHC8,KRIT1,CASK,DHRS7B,FAM169A,CCDC47,CMPK1,LBR,MAP2K3,SLC29A1,CAV1,PTPN1,SRPRA,HACD3,EHBP1,ACTA2,CDCA3,C2CD2,SLC2A1,POR,ESYT1,TIAM1,OSBPL8,MOV10,RELL1,HDAC6,RAB23,CDC42SE2,ATP1B1,DAG1,NF2,YKT6,B2M,SLC7A1,PIK3R2,UQCC3,TMEM209,CDC42EP4,PPM1G,HELLS,ITGA2,JUP,PICALM,STOM,SLC12A2,COQ8B,PDE8A,SNRPN,SEC22B,PIP5K1A,ARHGAP1,RPL13A,ARMC6,YES1,UBB,SH3BP4,FERMT2,GAB1,VAMP3,HYCC1,CTNNA1,ENO1,EIF2AK2,WDR45,SLC11A2,RPS12,EPHA2,XPOT,DEPDC1B,FLOT1,SSRP1,GSTT1,AHCYL1,SLC39A7,PCNA,STIM1,RPN1,PCDH17,PRKAG1,CSNK1E,FAF2,PPP2R1A,ACTN4,SPTAN1,ATXN10,PPIA,TMEM237,RAB11B,WDR6,MRTO4,PHB1,PLEKHO2,XPO5,RAB32,PIK3R1,WDR11,NSFL1C,CXCR4,VAPB,NOTCH2,TOR1AIP2,EHD1,ETF1,LRRC8A,SPCS1,ACTB,CHCHD3,MAD2L2,FAM91A1,PIGK,RPL37A,BLVRA,LMNB1,MYO6,SCFD1,SLC7A11,ILK,NIBAN2,PKP4,MRPL16,TOMM40,RHEB |
| 2.663e-05 | -10.53 | SLC18A1 (solute carrier family 18 member A1) | protein interactions | 6570 | 151 | 66 | 19454 | 5460 |
TMEM42,C2CD2L,ADGRE2,BTN2A2,PMP22,SLC38A7,EMC4,CD81,VTI1B,ANKRD46,ADCK1,SPPL3,CNIH1,TSPO2,TMEM97,RPRM,TMEM14A,TFRC,PTRH2,CTSA,OTULIN,TMEM14B,SELENOK,EMC10,INSIG2,NEU1,YIPF4,SLC29A1,MFSD6,TMEM205,NRM,RHBDD3,TMEM60,EMC8,STX8,EMC2,TMEM147,FCER1G,ZMPSTE24,VAMP5,CYB561D2,GJB2,SLC35B4,TECR,FAM91A1,PLP1,SYNGR1,PTPMT1,SMCO4,VAPB,SDC2,FAM8A1,FAM3C,GJC1,AGTRAP,ADIPOR1,PLP2,SEC22A,HACD2,PXMP2,STX7,DPH6,ORMDL1,RABAC1,NDUFC2,TMEM203 |
| 2.663e-05 | -10.53 | NOL12 (nucleolar protein 12) | protein interactions | 79159 | 151 | 66 | 19454 | 5460 |
SF3B1,NLE1,DVL2,BRIX1,NHP2,SAP18,STAU1,RPL4,NOP53,NPM3,FGF17,ZNF770,RPL26L1,MRPS18A,FGFBP1,ZNF189,RPL19,RPF1,RPL13A,ZCCHC7,CEP70,ZNF668,RPL7A,MYC,RIT1,H1-1,NSA2,RPS5,ZCRB1,FTSJ3,MRPS25,KIAA1191,FYTTD1,MRPS11,RPL31,MRPS18C,SRSF12,CDCA7L,CHCHD2,PAK1IP1,MRPS33,KRAS,H1-6,MAK16,RPSA,CDK4,SART3,SOD2,RBM34,KRR1,SRSF1,RPL8,MRPS9,SURF6,DKC1,LYAR,RPS16,RPS10,MRPS35,RIOX2,DDX50,NOL12,SSX2IP,MRPS26,RPS2,H2AC4 |
| 2.692e-05 | -10.52 | CDKN1B (cyclin dependent kinase inhibitor 1B) | protein interactions | 1027 | 137 | 61 | 19454 | 5460 |
CCNA2,CDK7,CDKN1A,CCND1,RPL27A,H1-5,CKS2,CDK1,NUP50,HSPA8,SKP1,CCND3,YKT6,KPNA6,BAG3,IRF1,CCNB1,MYC,AKT1,H1-1,COP1,HSP90AA1,YWHAZ,TXNIP,DCAF4,UBE2I,UBE2S,DCLRE1C,SRC,JAK2,UBB,UBE2L3,YES1,SIAH1,MAPK10,TRAF2,SUPT5H,CDK4,CKS1B,NHERF1,UBE2B,CAMK1,IGF1R,UBE3A,TRIM21,CDK5,KPNA2,YWHAG,XPO1,COPS5,YWHAH,WWP2,CLPX,YWHAB,KPNA1,PSMB1,CDK6,RCHY1,ARL11,PRNP,CDK17 |
| 2.697e-05 | -10.52 | MDM4 (MDM4 regulator of p53) | protein interactions | 4194 | 104 | 49 | 19454 | 5460 |
S100B,HAPSTR1,UBE3A,RNF115,PELI1,MNAT1,TP53,CDK4,RPL15,EZH2,SMAD3,RCHY1,RB1,HNRNPL,VPS26C,MDM2,USP2,YWHAH,YWHAG,SMAD4,UBE2D1,BECN1,YWHAB,MAGEB1,NBN,EP300,NF2,RPS15,UBE2D3,ASRGL1,PPP1CB,CDKN1A,CSNK1A1L,CDK1,HBB,CSNK1A1,ARF1,PSMC5,ALB,RPS20,TRIM46,APEX1,AKT1,SFN,PPP1CC,YWHAZ,HSP90AA1,EPHA2,COP1 |
| 2.705e-05 | -10.52 | cytoplasmic vesicle membrane | cellular component | GO:0030659 | 1230 | 421 | 19108 | 5553 |
ZDHHC17,RAB23,CLBA1,SYT2,CHMP1A,FIG4,RAB22A,RAP2A,GABRB2,SVIP,RAB3C,MYO6,LMAN1,CD14,NECAP2,TLR8,FZD6,KDELR2,AP3S2,PSENEN,RAB1A,SNAP25,SV2B,MYO1B,VAC14,DLG4,CD1C,SLC17A5,AP5S1,TLR4,CHMP5,SAR1B,LDLRAD4,CXCR1,MREG,CLVS2,OLR1,CHMP1B,ATP6V1A,B2M,SNX33,SLC38A9,STX16,TYROBP,CLCA1,CX3CR1,CD63,WDR83,CD4,TLR1,CYB561,VAMP3,ITGAV,CMTM6,TMEM59,PRCP,TMEM95,COPE,PIP4P2,CLIC4,HMOX2,RHOG,TMEM106B,TAB2,BECN1,SNX3,BORCS5,CORO1C,TMBIM1,GABRB3,ATP6V0B,DEGS1,VPS4B,TF,RPS27A,ABHD17A,RAP2B,ARHGAP21,CPLX3,MTMR2,TLR6,IL15RA,PDE6D,INPP4A,GPNMB,VPS33A,UBB,NECAP1,STX6,SLC18B1,LITAF,DKK1,RNF167,SAYSD1,TMED3,CTSD,SLC11A2,VTA1,BCL2L1,MARCHF3,ATP6V0E1,SLC2A3,RAB39B,TMEM199,TBC1D24,UBE2D3,STOM,LILRA3,AFTPH,PLEKHF1,RAB8B,SNAP29,CAV1,VAMP8,OPTN,SERPINA5,ATP6AP2,SLC2A8,RAB5C,PGRMC1,SNAP23,SYN3,ATG9A,SPG21,SERPINB10,RAB35,STX1A,IRF7,CDIP1,RAB9A,FCMR,SNAPIN,CHMP2A,NTRK2,GDE1,MCOLN1,STX12,HSPA8,CNIH1,LAMP3,MMD,FCGR1A,AP2M1,SYNGR4,TLR9,VPS4A,LAPTM4A,GNPNAT1,SPPL3,APH1A,RALA,VPS39,SCAMP5,ARHGAP1,RAC2,SYNPR,SLA2,LAMTOR1,TOM1,SLC1A1,TICAM1,SEC23A,SLC39A13,ATP6V1G1,ZMPSTE24,GPR89A,PLD3,CD1A,CHMP2B,STX17,COPZ2,TMEM165,SEC13,TMEM45B,SIGLEC5,KCNH1,RAB27A,TBC1D10C,TLR3,TSG101,SNX12,TMX3,FCAR,SNX1,SPRED2,ATP6V1D,SURF4,UBAP1,RAB4A,MME,CD3G,STARD3NL,SNX18,NDFIP1,TMED7,RNASEK,AP1M1,AP2A1,TOM1L1,TAB1,SCYL2,CYB5R1,SLC4A8,AP2S1,CD47,CLIP3,TNFRSF1B,DIPK2A,RHOB,DIO3,SLC32A1,SYT4,SYNRG,VPS28,AQP11,TSPAN15,TBC1D5,OCRL,CALR,WNT7A,APPBP2,CD1B,CFTR,CAMKV,HBEGF,SLC30A5,CD1D,PIP4P1,CD36,NCDN,RAB18,BOK,VTI1B,SLC12A2,ANXA4,VAMP2,TFRC,CHMP4C,SNX10,GABRA2,AQP2,ITM2B,EPHA4,SELL,SYPL1,RAP1A,USP8,ICA1,SYNGR2,CAV2,NDUFC2,TRAF6,FZD4,RAB3B,PDIA3,DBH,CD274,SEC22B,GLIPR1,TLR2,PICK1,WDR44,LDLR,AP1S2,SVOP,SNX5,SLC48A1,EHD3,KDELR1,HSD17B6,TICAM2,TMEM190,SGIP1,EHD1,ARCN1,SLC15A2,GOSR2,ANXA7,SLC35G2,LRP6,EXOC3,CYSTM1,NCSTN,GRIA2,B4GALT1,HGS,SNX20,CD164,CD46,RAB5A,GRIA1,NPC1L1,FGD2,VAMP5,AQP4,PSEN1,BST2,RAB14,SCG3,LAMTOR3,CD9,CALY,LAMP5,RND2,STX7,ABHD6,SNX14,TAPBP,ZNRF1,SLC31A1,AGTRAP,NSG1,UBXN6,ATP6V1C1,LAMP2,VPS26A,SEMA4C,CAMK2G,SNX24,RHOBTB1,GJA1,TLR7,LAMTOR2,SCAMP2,RAB13,STBD1,KLHL12,RAP1B,ATP8A1,PLA2G4B,PCSK9,ATG16L1,CPNE1,IRAK4,PML,BACE1,GAD2,FCER1G,RAB3A,CYB561D2,PRRT1,VPS16,IZUMO1,HPS6,SLC35F1,SYNGR1,RAB37,TMEM30A,VPS18,MYD88,NCALD,VAMP7,PLEKHF2,OR51E2,ARF6,GABRA1,DNM2,CLCN6,BRI3,FABP5,RAB31,SNX17,CIDEB,RAB6A,FURIN,RAB3D,GABRG2,ATP6V1G2,LY96,EHD4,RHOU,RAB9B,ADRB2,STX10,RAB11B,DNAJC5,PDLIM4,FCGR2A,CPTP,UBA52,ABCC5,STX5,AP1G2,CACNG3,DYNLL1,SLC6A4,TASL,RAB32,CD58,SYP,AP5M1,TMEM179B,CD59,LGALS3,WASL,CPE,MDM2,SYNGR3,ORMDL3,GABARAPL1,SYNDIG1,FOLR1,RAB11A,OPRK1,PARM1,LHFPL2,REP15,REEP6,SNX22,SNX2,SRI,ACAP2,RAP2C,YKT6,MRC1,TMEM108,VAMP1,SERPINB6,ENPP4,CLVS1,MOXD1 |
| 2.709e-05 | -10.52 | CKB (creatine kinase B) | protein interactions | 1152 | 232 | 94 | 19454 | 5460 |
ARMC8,HAX1,UBFD1,PDIA3,DDRGK1,YWHAG,PPIB,SUMO2,HNRNPL,CNTROB,GJA1,NGB,EZH2,MOB3C,RND3,RAF1,MSX2,EEF2,ACTN4,PPP2R1A,SOX2,VDAC1,RRAGB,HNRNPA2B1,UBE3A,RHOB,LMNB1,LAMTOR1,ILK,LDHB,CUL3,MYC,ACO2,ACTB,TAB1,USP38,DLST,ANAPC2,SNRPD1,ISOC1,PAK2,CNDP2,PGRMC1,B9D2,UFL1,PEBP1,PSMA3,AKAP1,HDAC5,USP15,CALR,MOV10,TPM3,API5,HDAC6,FZR1,G6PD,DFFA,AIFM1,NHERF1,TFCP2,MTCH2,HNRNPK,TRIM63,CSE1L,HSPE1,HUWE1,DUSP19,MAP1B,SOS2,PPTC7,RC3H2,UBE2H,PDCD4,AKT1,AR,PPP1CC,KCTD9,NDN,NMI,ENO1,CCNF,TRIM24,METTL14,HSP90B1,RPA2,LMNA,UBE2M,HEXIM1,SIRT7,BAP1,RPA3,SOD1,SQSTM1 |
| 2.730e-05 | -10.51 | RPRD1A (regulation of nuclear pre-mRNA domain containing 1A) | protein interactions | 55197 | 171 | 73 | 19454 | 5460 |
TFPT,RPAP3,TRIM21,EWSR1,MRPS11,G3BP1,DNAAF10,PDRG1,SSRP1,PTGES3,MAX,TP53,CENPM,RPAP2,JUN,GTF2E2,FNTB,DXO,ACTR2,POLR2C,POLR2G,SH3GLB1,POLR2D,HGS,EEF1AKMT3,POLR2L,SPPL3,POLR2I,NUF2,HMG20A,MOV10,ANKMY2,MED21,KDM2A,POU5F1,MED4,NUP50,KDM1A,MCMBP,OIP5,PITHD1,POLR1H,SNRNP27,POLR1D,RFXANK,SDCBP,RPRD1B,GOLGA5,GIT2,PIH1D1,S100A6,LMBR1L,SURF2,POLR3B,ALB,POLR2F,POLR3H,PHF21A,POLR2B,LMO2,MYC,RIOK2,DEPDC1B,GGH,MED10,BRCA1,MYO6,CYP1A1,YWHAZ,CCDC22,PFDN2,CCHCR1,POLR1B |
| 2.730e-05 | -10.51 | CCNA2 (cyclin A2) | protein interactions | 890 | 171 | 73 | 19454 | 5460 |
CCND3,SKP1,POLA2,TTR,EP300,RPA3,RFC4,HIRA,CKS2,RPA2,CDK1,CDK7,CCNA2,CDKN1A,CCND1,NFYB,H1-5,RPS14,USP6NL,TAF11,DYRK1A,CDC20,MAD2L1,PSMD4,ALB,EIF2AK2,MIDEAS,PSMA6,H1-1,DTL,ANAPC4,SP1,BRCA1,TFDP2,CCNQ,GMNN,SAMHD1,CCNB1,CREBBP,NFYA,TF,ANAPC11,KRAS,RPAP3,PCNA,CDK5,TBC1D4,SERPINA1,BTG1,E2F4,TP53,CDK4,CKS1B,FEN1,LRWD1,CITED1,PRKCQ,CDK9,TOP1,PGR,SPPL3,FZR1,RB1,CDK6,LDLR,IL10,MYBL2,CDKN1B,CTNNB1,COPS5,DNTTIP1,TAF7,DYRK1B |
| 2.730e-05 | -10.51 | MRPL3 (mitochondrial ribosomal protein L3) | protein interactions | 11222 | 171 | 73 | 19454 | 5460 |
MRPS26,HNRNPD,CHCHD1,SNRNP70,TMEM70,RHOG,MRPL18,HNRNPA1,MRPL9,MTRF1,GRSF1,MALSU1,MRPL50,CAND1,GATD3,FAHD1,PRR3,ALYREF,RPL32,SSBP1,MRPS9,MRPL51,RPL18,NDUFS3,METTL15,APOBEC3D,AURKAIP1,MRPL11,MRPL47,RPL17,H1-6,KRAS,EMC2,SRSF7,HINT2,PPAN,MRPL52,HSPD1,RPS5,TUFM,MRPL16,CIAO1,PMPCA,MYC,AUH,MTG2,RPL10,PRRC2A,RPL19,RPL35,RPL13A,MRPL23,MRPL13,MTG1,MRPL53,RPS3,CCNF,TACO1,MTRES1,FOXS1,MRPL12,RBMS2,TIMM13,MRPL10,RPS14,ATP6V1G1,MRPL41,MRPL17,RPS15,HSCB,GFM1,EXD2,NGRN |
| 2.737e-05 | -10.51 | oxidoreductase activity, acting on peroxide as acceptor | molecular function | GO:0016684 | 59 | 33 | 18094 | 5411 |
MGST2,GPX3,HBM,SESN2,CYGB,TXNRD1,GSTM2,GSTT1,IPCEF1,SESN3,GPX5,HBA1,SELENOF,PRDX4,PRDX1,GPX2,HBE1,ALOX5AP,CLIC2,GPX7,GPX4,MGST3,GSTP1,PRDX2,PTGES,GPX6,GPX1,GSTA1,GSTK1,HBB,PRDX3,TXNDC17,PRDX6 |
| 2.737e-05 | -10.51 | protein targeting to ER | biological process | GO:0045047 | 41 | 25 | 18204 | 5365 |
SSR3,VPS54,SGTA,TRAM1,SEC61A1,HSPA5,SPCS2,SRP72,UBL4A,TRAM2,SEC61B,SEC61A2,SRP14,SPCS1,SEC63,ZFAND2B,SRPRB,SRP54,SEC62,EDEM1,ZFAND2A,SEC61G,SPCS3,TRAM1L1,SRPRA |
| 2.737e-05 | -10.51 | cell redox homeostasis | biological process | GO:0045454 | 41 | 25 | 18204 | 5365 |
PRDX6,BOLA2B,KRIT1,TXNRD2,SELENOT,SELENOS,TXNRD3,DDIT3,PRDX1,GCLC,NQO1,PRDX2,ERO1A,GLRX2,BOLA3,TXNRD1,BOLA1,TXN,EGLN2,GPX1,PRDX3,GLRX5,PRDX4,NFE2L2,APEX1 |
| 2.759e-05 | -10.50 | KCTD5 (potassium channel tetramerization domain containing 5) | protein interactions | 54442 | 96 | 46 | 19454 | 5460 |
UBE2H,RC3H2,FAS,GORASP2,CUL3,RPL7A,FAM193B,CUL2,CNRIP1,GNB1,SMURF1,KCTD9,PRDX2,GNG12,GIT2,UBE2M,FGFR1,GNG7,CDK7,HSPA5,GNB4,FBXW7,UFL1,DGCR8,ZNF692,EP300,DDRGK1,GNG2,XPO1,EGLN3,CD1A,SPPL3,FZR1,GJA1,SRSF1,CD274,EFNA3,KCND2,NHERF1,TMEM45A,SOX2,B3GNT2,FBP1,RIGI,KCTD17,TNF |
| 2.767e-05 | -10.49 | KCTD10 (potassium channel tetramerization domain containing 10) | protein interactions | 83892 | 197 | 82 | 19454 | 5460 |
ATP6V1A,STT3A,AIFM1,SYNCRIP,NDUFB4,FUBP3,TOMM70,SURF6,DCUN1D1,HNRNPL,SNX1,KCTD10,SNX2,GTF2E1,COPS5,ATG7,EIF3D,KXD1,RPL6,LSM3,ABCE1,PCNA,PDIA6,FAF1,TCEA2,EDEM2,TICAM1,MRPL22,COPS4,CTNNBL1,NEDD8,TOM1,DDX39A,EEF1A1,PPP2R1A,IRGQ,YTHDF2,RAD23B,PLS3,RPN1,MINDY3,MRPL36,CFAP36,CAPZA2,PAPSS2,IREB2,RPL19,UBA3,CEP97,MRPS21,CPT2,ACTB,PSMD6,NTAQ1,BTF3,LMO2,TNFAIP3,USP13,CUL3,PTPN11,EXOSC1,IGF2BP1,NRP1,CDKN2AIP,LMNB1,HSPB2,HNRNPH2,DLAT,DDX5,TNFAIP1,MAVS,PPM1G,SETD3,STXBP1,ATG16L1,PAFAH1B1,UBE2M,LUC7L3,LMNA,GALNT1,USP39,SOST |
| 2.770e-05 | -10.49 | regulation of type I interferon production | biological process | GO:0032479 | 126 | 59 | 18204 | 5365 |
TRIM15,TIRAP,NMI,PPM1B,STAT1,MAVS,GAPDH,KPNA2,IRF7,TLR7,TYROBP,RIGI,TICAM1,OAS1,TRAF3IP3,CGAS,IRF8,POLR3F,TICAM2,IRF1,TRAF6,MYD88,TLR2,XAF1,PQBP1,CD14,CUL3,IFIH1,UFD1,KLHL22,TLR9,RNF26,TBK1,MIR21,BANF1,TLR8,IL10,POLR3B,TLR3,G3BP1,NMBR,LILRB1,DHX9,HSPD1,MIR26B,PTPN22,SYK,TRIM27,TANK,TLR4,FLOT1,PYCARD,TRIM21,PTPN11,HSP90AA1,ISG15,IRF3,TOMM70,UAP1 |
| 2.770e-05 | -10.49 | DNAJB11 (DnaJ heat shock protein family (Hsp40) member B11) | protein interactions | 51726 | 334 | 128 | 19454 | 5460 |
MET,EPHX1,HEXIM1,WTAP,P3H1,GRM2,HSP90B1,METTL14,GABRA1,AGO1,CFTR,ATG16L1,TPT1,HSPA5,IRF7,GTF2I,BAP1,NRP1,NAPA,UBE2H,SNX5,CALU,SDF2L1,DNAJC10,RUNX1,DNAJC8,CEP70,SPRED1,DDAH2,VIRMA,DYRK1A,SEC63,ACP2,RALA,CTSB,PNP,EIF4H,GANAB,CCNF,STUB1,FURIN,RNF8,PSMC3,DDX42,TFRC,GPX7,MAP2K3,RRM1,PSEN1,PRDX4,CAPZA1,HNRNPK,DNAJC30,ERO1A,EMC2,IGF1R,FAF1,TUBG1,DPP4,CALR,FAM20C,EDEM1,LMAN1,EPHB6,ATP5PD,TMPO,RNF128,SEC23A,AIFM1,PTPN1,EFNA3,FKBP10,ATP5PO,PPT1,PRDX3,TMEM231,EMC1,PTN,MCMBP,ADRB2,HSPA8,HDAC5,AKAP1,DDX5,DNAJC3,TMEM106B,PFDN2,NTRK3,CRMP1,ILK,FAS,BRCA1,RNF40,DRAP1,MYC,CUL3,CUL2,MAT2B,SEC61B,PELO,PLD3,EZH2,RPN1,HDAC11,TUBA1A,B3GNT2,GJB1,ROCK2,ERP29,PDIA6,BAG2,TRIM11,HSPD1,CCT8,PPIB,EIF3D,IFI16,PRPF19,GSTM3,PDIA3,EGLN3,NUF2,OS9,PCSK9,SNX1,SNX2,CORO1C,ANXA4 |
| 2.782e-05 | -10.49 | RPL37 (ribosomal protein L37) | protein interactions | 6167 | 154 | 67 | 19454 | 5460 |
HSCB,MRPL17,RPS15,MRPL57,RPL4,MRPL40,MRPL20,MRPS7,RPL27,SQSTM1,MRPS18A,RPL26L1,RPLP0,MFAP1,ATG16L1,UBA52,MRPL10,RANBP6,MRPL23,SRPK2,RPL22,RPS3,CTTN,RPL37A,RPS9,MRPL13,LSM14B,POLR1B,RIT1,H1-1,MYC,GRB10,MRPL16,KRAS,MRPS18C,MRPL22,RPS13,RPL17,RIGI,RPL31,RPL23A,HAPSTR1,RPS11,MRPL49,MRPL51,MRPL47,MRPL11,H2AX,RPL29,RPL35A,MRPL50,MDM2,WIF1,MRPL24,MRPS9,RPL12,RPL9,RPLP2,MRPL18,RPL24,SNRNP70,RPL23,RPL10A,DPP4,RPL6,WWP2,MRPL9 |
| 2.782e-05 | -10.49 | CSTF2 (cleavage stimulation factor subunit 2) | protein interactions | 1478 | 154 | 67 | 19454 | 5460 |
DDX1,AKAP8L,MAP4,KIAA1143,SNRNP70,CPEB1,XPO1,ANKRD10,MOV10,CNOT2,BABAM1,PAPOLB,CHMP2A,TOP1,PRNP,HDHD3,SSU72,FEZ1,NUPR1,HGS,AGER,NUP153,CSTF2T,METTL15,MAX,SSRP1,TFG,ERG28,EWSR1,PALM2AKAP2,PABPC1,CDC73,PFDN6,BRCA1,CYP1A1,RUNX1,CPSF2,NONO,SNRPB,PAPOLA,SUB1,CSTF3,ESR2,FBXO22,ANAPC2,CCNF,CPSF1,LMBR1L,UFSP1,HEXIM1,EIF4B,RPA2,CD2AP,CPSF4,ATG16L1,CDSN,LSM8,AATF,EEF1G,NOP53,KRT222,RP2,AKAP1,RPA3,BAP1,SNRPA,FAM168B |
| 2.784e-05 | -10.49 | organelle | cellular component | GO:0043226 | 14500 | 4322 | 19108 | 5553 |
HADHA,KDM1A,COPS7B,TNFAIP8L3,PHETA2,SCYL2,STRADB,POLB,RARS1,PDE8A,MORN4,TOM1L1,CD47,TMEM237,MTA2,HECTD1,SUV39H1,RRAGB,EDC3,ENKD1,GATD3,TNFRSF1B,NAA60,STPG4,PDE4B,NAP1L5,GTF2A2,CHRAC1,FCAR,ANAPC2,ANAPC4,FASLG,ERLIN1,SCAND1,APOBEC3D,DRGX,AP2A1,NKX3-2,CDC42EP3,NETO2,AK5,ALYREF,PPID,TRIM45,EXOSC4,SRGN,DNAL1,MIS12,USP46,MRPL10,CAMKV,TMIGD1,PRM1,HP1BP3,CRTAP,RPS24,TMX2,ANP32B,OCIAD2,CDK2AP2,CUTA,OPRL1,ACOT13,ORC6,TFPI,ENDOD1,STN1,NFIL3,ACOT8,TLR9,NPTX1,INTS12,OTX2,TEF,LRWD1,LIMS2,HM13,AMY2B,DCUN1D5,FOXA3,TMEM126A,PSMD12,TMEM170A,SNRPD3,MRPL24,TMEM50A,DAPK3,TGIF2LX,STOML2,ENO1,CDIP1,CRKL,FIS1,PFKFB2,ATP5IF1,ATP2B4,GRM1,DYNC1I1,NTRK2,SEC61A2,TMEM117,STAT6,HNRNPK,STAT2,MIR23B,CFAP418,TMEM165,PFDN4,MAN1A2,UBA3,METTL22,TBC1D10C,HDAC3,PAAF1,ENPEP,RCL1,DUSP9,TRAK2,IL6ST,TLR3,RFC5,SDF2L1,TCAP,PRR13,PSMD7,KRTAP12-4,CYTH4,SLC1A1,TICAM1,MAD2L1,XBP1,ABHD14B,GPHN,STX17,SSPN,NSA2,DTYMK,TMEM107,LCMT1,MDFI,NDC80,LDHA,CRYZ,EXOSC8,SMARCA5,GRAP,TEX261,IL15,H2AC4,PAK6,CD86,PPP2R5A,PRKX,GTF2B,PLPPR1,SPACDR,PDE6D,STX6,TRIM68,SURF6,AKIP1,PNMA2,FHL3,PARL,DEGS1,EMILIN1,HHIP,CAMK2N2,TNPO3,RAP2B,YWHAZ,FIBIN,BRIX1,CFAP119,TNNT2,SRPRA,TOLLIP,RPS23,RPL10,GADD45A,CREBZF,PPP2CB,LANCL2,SNAP29,CHGA,KCNA2,CDKN1A,NDUFB4,EFHC1,S100A10,DKK1,PDCL,P3H1,ZFAND2B,MPHOSPH10,HOXC4,NBN,MEAF6,RORB,SLC25A1,COA5,AGO1,TOMM20,PIWIL4,RBP2,ADD2,NUDT2,GLUL,CD14,ARF4,ZCCHC17,MGAT4B,GSTM2,F11R,CYP2R1,BRCA1,ZCRB1,SNN,SPRY1,DLG4,CAMLG,TMBIM6,ZNF862,GLRA1,H1-3,FIG4,CHMP1A,NUDT16,DROSHA,CHCHD4,PCGF6,NIBAN2,ATAD1,PELO,GABPA,PPP1R10,RPL12,IFT22,CD4,DNAJB9,POLE3,LPCAT3,CRYM,PNMA3,MEST,STMN2,FAM20C,MIR342,COPS2,PLEKHA8,CD1C,CCR6,TNIK,TRIM54,CXCR1,SIVA1,SLC37A4,STK24,TLR4,ACTR1A,DCAF5,TRAPPC14,MCHR1,RMDN3,AKT1,SLC38A9,PPFIA3,CDK8,GPRASP3,CRHBP,NAB1,ICAM1,ERG28,CFDP1,TSPO,FAM81A,PTP4A3,ZNF362,CHST13,CFAP298,UBA52,SDHAF1,VPS54,SLC39A9,TASL,ARFGAP3,DYNLL1,CEP19,CIB2,ARL5B,EHD4,NMRAL1,RAB9B,DDX5,EIF3K,NUF2,CD40,SNIP1,TRAM1L1,INSYN2A,PREB,H2AB1,DR1,CTTN,GRAP2,RPL7A,TMEM115,TM9SF4,TDRP,MECP2,ASPA,RAP2C,POU1F1,BRINP3,HCFC1R1,TIMMDC1,ENPP4,SPR,AP5M1,CD59,SERTM1,SMCHD1,MTCH2,REG1A,DCTPP1,NDUFB8,RCBTB1,SEPHS1,RNF133,UGDH,GNPAT,UBXN10,MAP3K11,IL12B,TOMM40,DUSP3,GNG7,GID8,HEXA,MSX1,TLCD3B,FBLN5,DICER1,ATG16L1,MAB21L1,RBBP4,FEN1,IFTAP,AK3,TPM3,GRSF1,RAB3A,ZNF575,RABL2B,MSRB1,SLC35A1,SPEF1,DCTN6,ATG7,MANSC1,ZYX,SPATS2L,CCS,ZMAT5,GTF2E2,SIAH1,POU3F4,ITGB8,WEE2,ZNF664,YAF2,RP2,TRAPPC2L,UBE2E3,CHIC2,MUL1,TP53TG5,SNAI2,TTC1,MOB4,SERPINB9,MAGOH,SLC38A1,CDK5,NDUFB10,TEX12,RBM34,RPL7L1,SLC38A7,EHHADH,PHTF2,NR2E1,TIA1,TMEM198,STK38L,CDK5RAP3,RAB1B,JAKMIP2,UFD1,VPS18,IRAK1BP1,AKAP12,CYSTM1,B4GALT1,RNF34,CD164,LHX2,SETD9,CDC5L,MIR107,AKT3,SOST,GADD45B,S100B,VRTN,SSX2IP,MACROH2A2,TAFA1,INSIG2,RBM12,MIR193B,MRM2,IGF2BP1,TSPO2,SLC30A7,CKS1B,DNAJC19,S100PBP,TXNRD3,KICS2,WDR55,CDC42EP4,LCA5,KIF2A,SLC25A17,PRKCQ,LSM6,ZNF655,CLEC18A,TOR1AIP2,IFIT2,TOMM7,MIR30A,CNTN1,PSEN1,GABARAPL2,ABHD6,STX7,CSNK1G3,SF3A1,NOL7,PSMA5,PTPN22,GH1,CCNY,PRSS37,MIDEAS,COA1,CGGBP1,NAE1,NHERF1,AIFM1,NPPC,ATP5PD,ARFIP1,NUP107,HSPB2,POLR3F,CYRIB,BORCS8,CEBPE,BLOC1S3,FCHO2,CYP1B1,TRIM29,CSKMT,NCDN,GNPDA2,RAB18,BAALC,SLC35E3,PRKAB1,SAT2,ARMC8,LRAT,RNF121,CYB5R3,MIR31,UBE2B,EPHA4,BCL2A1,GABRA2,FANCG,ZBTB25,CCDC92,H2BC12,CATIP,CYP21A2,SNX5,NUPR1,RPS16,DHX16,NDUFAF6,TACR3,KDELR1,EZH1,EHD3,BAG2,GLRX,SLC48A1,MARS1,SDC4,UBL3,YIPF4,HEXIM2,DRP2,DDX39A,CCDC69,NT5C3A,PIGA,SLC52A3,PSMA3,RAB33A,SUGP1,CSNK1E,RAD1,PROS1,NOSIP,OAZ1,PSMD3,APEX1,CDKN3,FGF7,CD247,METTL18,S100A8,TAB1,RIT2,NLRP6,CYB5R1,BUD31,MRPL20,MMAA,SNRPB2,PPIA,DIPK2A,SELENOI,SPATA2,CAPZA1,MIR198,MGAT1,SDHAF2,NLRP1,MLLT11,MCAT,FAM20B,TOM1L2,KCNJ8,CEP41,ST13,AP1M1,POMP,SNX18,CNIH4,CALR,PPAN,MIR130A,SERPINH1,MKLN1,PRICKLE2,BABAM1,CD1B,SDHAF4,ATF4,CSE1L,SIT1,NR1H2,ELF1,MRPS35,PRR19,PIP4P1,IL6,DYNLRB2,SLC30A5,EMC9,MIR10B,TSR2,CAMSAP2,DIO3,OGDHL,CAMP,UBE2M,NOP53,SPRED1,SLC25A42,SLC25A27,RASL11A,GLT8D2,NFKB1,TGIF2,MDH1,MIR34A,MRPL41,PSMB9,SYNGR4,TTR,CSTF3,EIF2S2,TMEM91,MYL6,RANBP1,DRAM1,SNRNP27,LRRC4,BMP1,SPRYD4,NF2,FAF1,INA,KCNJ10,B3GALT1,CAPZA2,SLC2A8,HMX1,PELP1,SH3BGRL,WDR5B,TOMM22,NLRP2,WDR3,HPF1,FTSJ1,ARL2BP,MAPK4,CLIC2,TAL2,HNRNPC,GLIPR2,MAP2K6,HNRNPH2,DPAGT1,B9D2,GAMT,SLC13A5,USP16,ZFAND2A,BRMS1,RPL6,B4GALT3,RPS28,BGLAP,FBXO32,ALG5,RFX4,RDM1,TSPAN3,H2BC1,KRT7,STC1,SYNPR,FGFR1,RPLP2,SKA1,ARPP19,VMAC,TMEM176B,MRPL9,PSMB5,CAVIN2,GOLPH3L,ZMYM3,COX8A,PRKRA,H2BC14,MIRLET7C,SOX9,GOLGA7,PLEKHO2,SPATA4,PPP1R18,DAD1,ING1,RAF1,TLR6,ROMO1,MRPL52,S1PR4,CD248,SNRPB,COX4I2,INTS6L,JMJD8,PPIB,CORO1C,PPIF,CDC40,TMED5,LPAR1,MIR125A,NACC2,VPS4B,FGF12,SPOPL,PLPP6,NME2,TF,MX2,FBXO25,HSD11B1,GJB2,SLC2A3,ATP6V0E1,TMEM208,TXN,ST6GALNAC3,TMEM127,SNCG,SERPINB1,OIP5,CD34,LITAF,ZBED3,POLR2G,GALNT4,LHFPL4,TUBB4B,NCK1,HPGDS,ZNF581,MIR423,TMED1,HACD3,PTGES3,MOB3B,MAPKAPK3,ABCG2,TRIM26,ATP5PO,BBS5,TNFAIP1,CCDC172,IRF2BPL,TGFB2,ERH,TAF11,GALNT17,CYB5B,YWHAB,PIGY,TMEM50B,VDAC1,TRAPPC4,RAG1,KCNB1,B9D1,CYP27B1,FAM50B,ZDHHC17,ST6GAL1,GKAP1,DENND6B,RNASEL,DNAJB2,IDH3B,FGF23,INSM2,RUNX1,SCG5,EEIG1,NGDN,RNASET2,ATP1A3,PSMB10,DECR2,OXSR1,AZIN2,BICD2,IRF6,FKBP10,CBLN3,TYROBP,LRRC4B,SP1,FTH1,AASDHPPT,TNFAIP8L2,RANGRF,RIOX2,BACH1,MAFG,CFAP95,SRP54,TNF,PITPNB,RPL7,MIR26B,RBM15B,SST,PAXX,RGS2,GNL1,MRPL23,HNRNPH3,SLC25A31,TMEM203,PEX3,HBB,OAS1,GAL3ST1,CHDH,BCS1L,WWP1,DTD1,STX10,SLC8A1,OSGEPL1,HSDL1,STX5,MIR152,CHRM3,EIF5B,LAP3,MAIP1,AKAP17A,BUB3,RAB3D,ZNF704,TLNRD1,SNX17,LRRTM1,CFAP36,TSPAN5,DMAP1,SOD2,LY96,GNG2,LSM10,GLRX2,NLE1,IPP,MIR17,CELF6,SNX22,GORASP2,TMEM70,THRAP3,WTAP,SRI,SNX2,MRC1,SLC7A14,LUC7L3,HSD17B11,UTP15,ZNHIT6,SERPINB6,RB1CC1,KDSR,R3HDM4,EPOP,RPS13,MINAR2,TMEM97,HOMER3,CPE,NDUFA1,PNPLA8,LGALS3,BPIFA2,PLA2G5,SLC41A3,EIF4EBP2,CFAP73,BRMS1L,CHCHD6,RAB6B,PAK1IP1,GABARAP,MIR24-1,ZNF287,AK2,UNC50,PSRC1,SUMO3,CETN3,RAB29,C1GALT1C1,GPX2,JUN,TRIM32,RPL10L,PDCD10,GAD2,MIR92B,HSD17B10,ARFGAP1,ELOVL4,TMEM89,GASK1B,APOBEC3G,MSMO1,SRSF2,MIR146A,APTX,CYP39A1,SYS1,IGFBP4,GSTA2,MCM8,LAMTOR2,TLR7,ESR2,COPS5,ST3GAL4,TOR1B,EMC4,TFIP11,CTNND1,DDX4,OR51E2,ELK1,NOC4L,PLCB1,TMSB10,FABP5,LRRC8B,B4GALT6,GNAI2,CFAP20,FITM1,CNR1,PCLAF,MRPL16,HERC4,MCM6,H2AC25,JAK1,TAGLN2,RBIS,IRF2,ADAMTS1,COMMD8,LMBRD1,ABHD2,SPECC1L,CRAT,ABHD10,IRF8,OTUD7B,SEC14L1,VPS16,ZBTB42,B4GALT7,SSRP1,RPL26,LEMD3,RAB37,HOMER1,CRY1,COX4I1,DESI1,FAM168B,ENTPD4,SH3BP4,SOD3,GHR,NCSTN,UBAC2,NOS1AP,FKBP4,TPGS2,PC,DEFB1,TOPORS,QTRT2,COX5A,LYPLA2,VAMP5,PRKAG1,RNF208,COMMD9,TRMT10B,XXYLT1,ZNF330,NAP1L3,CARD19,EHD1,MAGOHB,PLP2,ACO2,BAHD1,SLC15A2,B4GAT1,HMCES,EXOC3,HDHD5,GEMIN7,ZNF345,VGLL4,ATXN10,LBX1,NDUFAB1,EEF1E1,ATP1B1,TMOD1,LAMP2,ZNF501,ORC5,CBLL1,PRMT2,ZBED4,PARP2,MAP3K14,CYC1,WDR83OS,CCT7,UPRT,STX18,PPP1CB,PRRC2A,TRAM1,PRDX6,BSCL2,GSTA1,MPST,NAA16,CLRN2,LIAS,UQCC6,MTA3,OCEL1,IKBKB,FA2H,TRMT112,ZNF518B,SFRP1,GOLGA5,GINS3,CPSF1,CAV2,CHST9,TCP11L1,GRXCR1,PRSS12,SPCS1,SLC12A2,MCRIP2,ATP5MC1,SNRNP48,NAIF1,VAMP2,ANXA4,VDR,RPL19,AQP2,SNAPC1,TOMM40L,ACTR2,DPH3,SVOP,CLK4,KCND3,HS3ST5,MINDY3,COX19,RNF40,IFT57,ADNP,GBE1,ZNF576,TICAM2,MED21,GPR85,MZT2B,FAM107A,DPEP1,NEUROG2,MTG1,BPIFB1,FZD4,HDAC6,SLC25A11,TCEA2,TP53INP1,MRPS28,MX1,PYGM,MRPS25,PACSIN3,TMT1B,SUPT5H,HEBP1,SFTPD,SYK,CWF19L1,MIR191,GRID1,ZNF365,FXR2,AP2S1,ENY2,BCL7B,ZNF250,RAN,CBX5,TAMM41,HCLS1,KLF9,POLR2D,FKTN,SWAP70,ATP6V1D,FAM161A,USP5,ELK4,UBE2V2,SNRPA,HSPB8,LYNX1,MCM3,LMNB1,ZC3H15,ETFA,TXNL4A,TESK1,NAPA,HNRNPA0,TACO1,BAX,PCK2,KCTD17,CTSB,PDIA6,MARCKSL1,GSTT2B,TOX,PTP4A2,RNF7,RBM38,POLR2I,TPPP,FNTB,CCND1,HSPA13,CCDC22,EFCAB7,MRPL12,ACTA2,MITF,ZNF175,XPOT,TNFAIP3,MRPL49,CYP27A1,HMG20A,CFL2,DNAJB6,KRAS,COX10,RASD1,GNPDA1,MGMT,PLAGL1,RGMA,PET117,FKBP14,TESK2,MIR30D,LAPTM4A,TUBA1B,GNPNAT1,PDCD5,RALA,FCF1,SERPINA5,PSMC4,CSTB,AGPAT1,ABITRAM,TMEM87A,SGMS2,UBE2N,SF3B1,EP300,ZNF326,SNTA1,DCAKD,PPM1B,CD40LG,SLC25A12,HILPDA,PKNOX1,EXTL2,ZNF513,ATP1A1,FRA10AC1,MAP1B,ZBTB39,AKR1A1,GANAB,CNPY3,NXT2,INTS10,PEX26,RBM18,PADI2,PEX13,GPR89A,AP1AR,STX8,CHMP2B,ALDH1A3,HBP1,CCT8,TAF10,ETFB,ZDHHC14,PHF1,DIPK1A,MTMR2,ARHGAP21,EMC8,TGFB1I1,TMEM59L,LDOC1,CTSA,DPP4,MLF2,FADS2,PSMB6,USP15,TRAPPC13,PPP3R2,RIGI,IFNAR1,SPOP,ZMYM6,ZSWIM7,NECAP1,VKORC1L1,ANKRD6,CLPX,ZNF821,STOX2,MAPRE2,TAB2,TMEM106B,OST4,PGR,ATF1,NFYA,LSM5,FAR2,FAM53C,LYSET,MIR185,ABHD17A,RPS27A,RPL4,ZC3H7A,ZNF622,TBC1D24,ZMYM2,RETSAT,GPT,TOP1,UBXN2B,PLEKHF1,RAB8B,SERPIND1,MAP2K1,SHOC2,LILRA3,HNRNPD,RPS2,PPME1,ISG20,RNF167,TMED3,CTNNA1,TRAFD1,METTL14,KBTBD6,CTSD,EIF2B5,GCC1,VTA1,STRBP,TLR8,CCAR1,RPL32,FKBP1A,PGA4,NECAP2,POLE4,CDC26,ING2,TMCC2,CH25H,SERTAD3,RANBP10,MIRLET7D,VIPAS39,DUOXA2,MYO1B,TBC1D17,TRAPPC1,ASB11,BRD9,KCNG3,B3GALNT1,IDH1,CTTNBP2NL,RPS11,CCIN,BOLA1,TPBG,SELENOP,GON7,PTPN4,RALB,VXN,AKAP8L,ZNF770,NTAQ1,HIGD2A,CFAP161,STX16,MAP2K3,GARIN2,BEX3,CHID1,SLC39A7,PIWIL2,MED17,BAP1,HMOX2,ACP6,PRPF19,TMEM14A,RNF128,SEPTIN7,CXCL14,SPMIP10,TNPO2,LDLRAD4,H2BC11,FNDC8,OLR1,MEIOB,ELOC,DHRS7B,GOLGA7B,SMU1,DEK,PSMB2,KRTAP4-1,FKBP2,HACD1,JPT1,ALKBH5,DNAJC5,HSPA5,PDLIM4,H2BC9,IFI27,EIF2D,RBPJ,PIWIL3,IL18BP,CPTP,CEP97,JAKMIP1,ARMCX1,ARL14EP,GARRE1,COX6C,CYP2F1,TLE1,FUBP3,SHISA2,RHOU,XRCC5,FOSL2,E4F1,SRSF10,LTO1,MAGEA4,RER1,GALNT2,USE1,CREBL2,FMO2,LHFPL2,PYCR1,USP38,GHRL,CBX7,MIRLET7I,GSTO1,LMO2,RPL29,MIR214,EID2B,ELF5,RPE,TMEM108,LACC1,MIR223,NABP1,VAMP1,MYEF2,SIAE,MSRB3,PIWIL1,FGR,WASL,NFKBIB,ZNF671,MARCHF9,NUDT7,MDM2,MLC1,NIPA2,CYP3A43,UBE2W,EIF4EBP3,ARHGAP19,AURKAIP1,MYC,SPCS2,ZBED1,MACROH2A1,COMMD5,ST8SIA5,CHST11,PRMT6,SOX3,ACP5,PTPMT1,STXBP1,ZHX1,GGCX,NOP9,PTTG1,PMAIP1,KIF3B,EXT1,MMP9,MAT2B,SIX5,CCDC3,DCLRE1C,SELENOM,POP5,DCUN1D1,ALDH1L1,CCDC47,SMC4,NKRF,SEPTIN6,MED31,UPF3B,RAB13,SCAMP2,TFEB,SLITRK1,WDR20,SSR2,AQP3,IRF9,ATP5MC3,MIR671,RPL22,ZNF207,CLDN14,BAK1,BRI3,SLC25A5,MTARC2,DNAJC8,NRBF2,ARL6IP5,TAF1D,RAB31,OSBP,H2AC1,RDH12,SYNGR1,PDE12,HPS6,TCF19,RPL13A,GOSR1,P4HA2,FGF10,PHYH,TAX1BP3,FOXI3,KLK9,RPRD1B,IL1A,NOL12,FEM1C,H1-1,PAPOLB,CCDC90B,GRIA1,RNF103,CYP3A5,GATAD1,MT3,MRPS7,ZNF189,MRPS17,HNRNPDL,CCDC174,BEND5,TAS2R46,UBE2S,GTF2IRD1,AAMP,SUB1,COTL1,FOXD3,VEGFA,PTPRQ,NAA11,RMI2,TOMM70,COX14,TFPT,IFI16,EEF2,SFXN2,ANXA7,ARL6,NRSN2,EEF1B2,KCND2,ISG20L2,CARHSP1,ZNRF1,H2AJ,RGS7BP,FBXW7,DDX39B,BORCS7,CAMK2G,SDHC,MMUT,ST3GAL2,PHB1,RHOBTB1,TEX264,ZBTB33,RPL28,MIR21,GLOD4,DNAJC24,PPP4C,PDLIM3,ZNF280B,MSN,MACIR,CASC3,CNOT8,CNDP2,ADD1,FUT9,CPEB1,ESYT1,CD9,ARL4D,ZNF7,HARBI1,GGPS1,TRAF3IP2,TTI2,DNAAF10,TUBA1A,SYPL1,TESC,JRKL,PCBD1,RBM41,XPNPEP1,PRKD3,DLAT,GFI1,CMTR1,ROGDI,RBMS2,FDFT1,RPP25,CHPF,RBBP9,PSMC1,H2AZ1,KRT222,TADA3,EMC10,PAGR1,HSD17B3,RIMS3,BLOC1S2,AIP,FATE1,SHC1,FBXL4,RPS7,CCDC134,KPNA6,RGP1,PLA2G15,CNN3,TMPO,EFHD1,IFI6,IL2RB,MRTO4,SMAP2,MRPS33,SMURF1,PPM1K,TSC22D3,PPIL4,SPTBN1,LDLR,ANKRD34B,RPF1,AP1S2,UBL4A,RPL35A,NDUFA5,RHBG,ROCK1,NUDT1,EIF2S1,ADCK1,UBE2I,ZBTB38,PHC1,PAK2,F2,MIR192,CRHR1,ANKRD49,TPT1,CXCL12,MCCD1,MMADHC,SNX12,AJM1,UBAP1,CHI3L1,DHX9,SURF4,MAP1LC3A,TRUB1,PIP5K1A,PI15,TMED7,TMEM174,HIGD1C,CTBP1,DNAJC30,SPATA6,NDUFS3,KRIT1,CIBAR1,NR1I3,ZNF692,DDAH2,NECTIN2,SEMA3C,PPP2R1A,HAX1,ARMCX3,NDUFAF3,ANP32A,PROM1,RSBN1L,DDRGK1,PDHA1,RHOB,GNPTG,TAF7,DTWD2,KLF4,CDK5R1,PRMT5,CMC1,OTULINL,DDIT4,HELLS,SKA2,FCGR1A,PDE9A,LSM2,LAMP3,ISX,CPSF4,CTDSP2,VPS4A,LIMD2,ARHGAP1,VPS39,DBR1,EGR1,RGN,DUSP10,RNF187,UST,CCNH,NCBP2,LDB2,FCMR,ADGB,FAM241A,SRPK2,TRIP4,DENND2D,RPL9,GDE1,RPS20,PTPN5,DNPH1,RPL15,GEMIN8,SELENOS,LCP1,CTDSPL2,LRRC8A,DDT,RRM1,PDP2,NR4A2,RNASE1,FAM149B1,YWHAH,TMEM106C,DUSP21,CENPM,KLHL7,RAC2,MED13L,AOX1,DPM2,HLF,NUDT12,PMP2,MYOZ3,COPS7A,MIR100,PAQR3,TRIM8,SGMS1,OSBPL8,RHEB,NICN1,ADIG,FOXC2,CHRNB2,GPNMB,INPP4A,DLG3,MARVELD1,ZNF319,IMP4,SPMIP5,VPS33A,PPIG,PFDN5,PABPC5,TAF2,GLRA2,MIR101-1,CMKLR2,NUDT4,EMC2,MAP1LC3B,MSH6,MAGEC2,PEBP4,PLEKHO1,UBE2H,DNAJC10,TMBIM1,TNFSF13,SNRPN,MRPL40,IMMP2L,CACYBP,FAAP100,MED29,CKB,SAV1,SPMIP6,TTC23,ADSS2,ZBTB18,UBE2D3,STOM,SNRPD2,ISCA2,CSGALNACT1,CPT1B,JAGN1,CAV3,REEP3,RNF14,MED23,SMCP,MTX2,APOC2,SLC25A39,PRSS8,PSPC1,TMEM177,CFAP61,PYURF,HENMT1,FAM76B,YIF1A,PITPNA,KDELR2,SLC25A51,CXXC5,HAPSTR1,CREB3L4,TRIM52,SIRT7,SV2B,EIF4A3,PSMD10,CHST7,CTSK,AKR1B1,MNAT1,SPOCK1,RNF126,GPR83,IFI35,RFXANK,FAM241B,EGR2,RAP2A,DYNLT3,NAA50,RPLP1,RWDD3,STAT5A,RELL1,RNASEH2C,RAB3C,CATSPERZ,CASP12,EXOC8,CGRRF1,SPTSSA,FBP1,SMARCE1,P2RY1,TLR1,SAP30,KLHL3,VAMP3,ISOC1,ACTL9,ENO2,PRCP,MRPS11,DMPK,LEPROTL1,SAR1B,CDCA7L,HSDL2,TMEM256,S100A11,PIK3R2,LSM8,RPL17,DRG2,TXNL1,CLDN8,GIMAP2,PSMA2,DUSP26,RAB28,IPO8,EMC6,STT3A,MAD2L2,UFM1,NPY,PSMD4,CPSF2,TRMT61A,RPS4X,HYPK,CIDEB,EDF1,CUL2,RILPL2,GABRG2,RFC2,MYORG,INO80C,NXT1,STAR,STK26,RPL39,PRDX3,NONO,EXOSC3,GTF2F1,CEBPG,MIR215,MIR619,GPR37L1,PRNP,HOXB8,FAM210A,EPS8,BCL10,TIMM8B,CYTH2,FRMD8,ZNF22,CLVS1,TRIM36,NEFL,IGF1,TMEM179B,RETREG3,ZFP64,KLF10,NFE2L2,NPC2,EEF1A1,RGMB,RAB11A,TUBB,RNF115,TLDC2,SPON1,CBX3,STBD1,PSEN2,FLRT3,HAS3,TBC1D25,USP14,ILVBL,RTF2,TOP3B,PML,AKR1C1,TMUB1,KARS1,COX6B2,KRR1,SPRN,MRPL57,EIF4E2,PALS2,CYP4F12,GPAM,GSTP1,ZSCAN25,ZNF687,DNAJC25,NUDCD3,PAFAH1B1,ARPC2,ATP5MG,PWP2,RBFOX3,ERLEC1,PDE6A,ARPC3,RXRG,FAM91A1,CSRP1,GCA,WSCD1,TWNK,ZNF177,CEND1,TNFAIP6,CRYBA1,BIRC2,HADH,ASTN1,SFN,PNP,ASPM,SETD5,MAPRE1,BEND6,NCAPG2,NLRP3,SLC66A2,ADGRG1,CD52,RAB5A,PKIA,NGB,TNFAIP8,SESTD1,FAH,ALG2,GNB3,TRIM27,MRPL47,PPWD1,NOVA1,FBP2,KANSL3,MYH1,SLC1A3,SMAD2,MIR20A,RNF139,ZNF343,CCT2,KLHL1,CREG2,CYBRD1,DET1,LRP6,NGRN,MBD3,LBR,COQ10B,TMEM126B,NAA30,ATP6V1C1,PSMB1,OVOL1,TIMM21,AIPL1,LINC02914,BAG3,PPARA,BST2,HEXB,RETREG1,FLRT2,ATOSB,AQP4,CACNB4,TUSC2,GCNT3,SCG3,DLX1,MRPL36,CYP11B1,GNG12,GALNT1,F7,TMEM33,CALY,NEK2,CEACAM5,TAPBP,UQCRC2,NAA35,PTN,ARMC1,GAPT,AZIN1,SRSF7,ILF2,EIF3G,ARHGAP5,G3BP1,NDUFB7,SEC61G,SRFBP1,ZCCHC7,CNTROB,ST3GAL5,ELOVL7,GPBP1L1,YPEL4,MED11,COA4,ST8SIA4,CHMP4C,ZC3H11A,SNX10,MAEL,CSRNP3,TFRC,ITGB5,PBLD,HBA1,KLK5,PSME2,TRAF7,NPTN,TMEM100,CDH13,PYCARD,GAS8,TRA2A,GGCT,MEF2C,MZB1,MAVS,BNIP3L,PPM1M,FHIT,POLR1H,ARHGAP15,FAM8A1,INSYN2B,TBCEL,CBR4,PXMP2,EIF2AK2,TRMT1L,FMOD,PDIA3,PQBP1,NDUFC2,RAPGEF5,STARD7,PAFAH1B2,GLIPR1,CYP17A1,DBH,MRPL34,FBXO3,NUFIP2,CDNF,ZCCHC12,DMTF1,MKKS,KIF1C,SDS,FAM118B,NTMT1,DFFA,MT1X,SATB1,SFRP4,CLIP3,SFTPC,NFKBIA,ABCB9,MIR197,LAMB2,EEF1G,VWF,BOLA2B,CLK1,HNRNPF,AGPAT5,MTRES1,METTL21A,ZNF322,UCKL1,SCN3B,BTF3,MRPL50,STX11,CXCR4,FABP7,SIN3A,RNF10,TBC1D1,GNAI3,RNASEK,WDR19,LMNA,RPL27A,WDR77,SLC35D1,COX6B1,CMA1,GGH,ZFP1,MSMB,SLC22A12,KCNF1,B3GALT4,MIR9-1,CD1E,RPS12,TCEAL1,ARL4A,GNB1L,CREBBP,FBXL3,ID1,TRMT5,CENPL,SSBP3,TRIM37,YES1,PHYKPL,RPAP2,PLAC8,CEP70,TRIM5,CASK,CAPN1,MIR193A,SLC35F6,PSMB7,CSTF2T,VCPIP1,SMAD5,VPS28,AQP11,COQ8B,MOV10,TMOD2,ARMCX2,TM4SF20,SORD,COMMD6,CNIH1,STX12,MMD,RND3,TRAPPC3L,THAP6,SRSF1,CMTR2,SLC35A5,RBBP8,AVL9,DES,PHACTR1,LYPLA1,XPO1,DHRS4,CTNNA2,IGFBP3,NKAP,BRAP,GPX1,ARFGEF1,POLL,SYN3,GHITM,RAB5C,VIRMA,CRADD,PRKCB,SLC25A28,RAB35,CHCHD3,PEDS1,RHOBTB3,TMEM209,SEC13,NTF4,MIRLET7B,ZNF805,CA2,RAB27A,GPAA1,RPS10,LMBR1L,KCNH1,TRAF3IP3,TMEM11,GMNN,NDUFA4,PDIA2,CERS2,ATP6V1G1,SEC23A,SLC39A13,SPMIP9,ARGLU1,KDM4B,PLD3,ZC4H2,PPP5C,CD1A,DIO1,SH2D5,JAK2,WDR12,TFG,LAT2,SRC,DDX23,BMPR2,DCK,EEF1AKMT3,SCG2,CLTRN,MRPS16,POGK,BCL9,ZNF526,TAF9,SLC25A21,TFCP2,GSK3A,PPM1G,PHF21A,ATL1,NDE1,ATP6V0B,ZBTB14,PDE2A,MPP1,SQSTM1,MYG1,CCNI,SLC22A8,ST3GAL1,TMOD3,NFYB,CSTA,RAB39B,PYGB,NAPG,MORF4L1,CENPW,CDH11,ANKRA2,MIR422A,INPP5K,PIH1D1,ELK3,MTDH,ACO1,ATP2C1,SHLD1,RPL18,SYNE4,BPNT2,SAMHD1,SLC35C1,FMO3,RRAGA,FKRP,DNASE1L1,BCL7C,ZNF688,LIN7C,CRABP2,MAGED2,MGP,CAMK1,IL1B,ZNF592,SLC11A2,CDC42EP2,RPL24,CHRDL1,BCL2L1,OSTM1,PRKCA,NSMCE3,FOXJ3,SIGMAR1,ALOX5AP,RPL31,GPR137,FKBP1B,ABHD5,WDR11,COX7B2,SS18,SETD7,SNAP25,DAG1,ZCCH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ACAA2,MYLIP,CCSER2,NETO1,ATP1A2,MGAT4A,COPS4,MIR30E,GSTO2,GK2,BTG2,TBCE,AKAP1,USP8,NUP35,IER2,KPNA2,CCDC42,TSPYL4,LSM3,LHB,GSTM3,PTHLH,CD36,MRFAP1,MIR126,ELP6,PSME1,SUPT3H,STAMBP,LGI1,LLPH,ZHX3,HERC3,ZDHHC24,DVL2,GLCE,EDEM3,PRELP,ANKRD10,IP6K1,MSL2,SP4,CDK12,DEDD,IMP3,HSBP1,PTDSS1,PHF7,STAMBPL1,TMEM167B,NR1I2,TRIM21,LUM,SCLT1,CD81,ADH1B,CFAP90,DNAJC3,TDRD7,LPAR2,MIR29A,KRTAP8-1,SERPINA3,CCR7,CNOT6,INPP5E,BCCIP,TRA2B,BANF1,DNAL4,LDB1,RCHY1,SLC4A8,PDE7A,CREB3,GTDC1,SPRED2,PTRH2,SELENOF,BFAR,KMT5B,TRIM3,CNOT7,MIR15A,UGT1A1,MYL12B,CYBC1,TBC1D5,OCRL,WNT7A,POR,CRISP1,COP1,TRIB1,PRPF31,RTKN,PPIC,CD1D,LYZ,DBT,MYCT1,DNTTIP1,RABAC1,CDC42SE2,CISD1,C1D,APOBEC3A,LYZL4,KXD1,CBL,METTL6,SETD3,SF3B4,UGP2,PRDX1,CYTH1,PMM2,CAPG,STARD4,H2AC6,MAF1,IFT25,AGK,TRIM46,GPC4,CDK9,NAB2,ACACA,LGI3,SLC20A2,UHMK1,FUT1,MT1A,PDSS2,NQO1,THG1L,SCAMP5,ACSL4,CHRM1,APH1A,WDR37,CCR5,GNB1,TEX19,ADK,ARF1,TMEM123,CNOT2,URAD,STAP1,BUD23,DYNC1I2,TVP23B,SFT2D2,RPS6KA4,HNRNPL,PGRMC1,RAB9A,CAP2,YPEL5,STX1A,HTRA2,SERPINB10,ARL15,AVPR1B,SUMO1,POMT2,CHMP2A,VGLL2,MCOLN1,CHST2,TPPP3,FUNDC1,HRAS,CSH1,TIMM23,EMG1,PRDM4,CDAN1,HOXB1,MGME1,TAX1BP1,NUP153,HAUS2,RBM22,GALC,GLRX5,NDUFS2,LAMTOR1,NUS1,PSKH1,ZNF652,PEG10,NUDT9,TTL,RPS17,TIMP3,IL12A,KLK3,RPS5,SYCE3,PDHB,SLC25A44,TUSC3,RMND1,ADRB1,DPY30,SMAD1,SLC1A2,PYM1,RNASE6,MIOS,CCN3,G0S2,TPPP2,CWC15,ANAPC11,AGR2,PTPN11,EMP2,IL15RA,MLF1,CHAMP1,RNF152,UBB,ZNF473,PTEN,ABHD8,CIMIP2C,CDK17,PPP1R12A,PPP1R11,CSTPP1,TM9SF1,MYH2,BTG1,OLFM3,LCORL,GABRB3,ERRFI1,BTG3,PAPOLA,SYBU,CRYGB,CFAP91,ZNF263,RAD23B,TIRAP,AFTPH,GTF2H2,TRNP1,REG1B,TBCCD1,RAB19,GNB4,SPMIP8,TSNAX,OVGP1,GTF3C4,TIMM10,EMX2,EID2,AUH,DNAJB4,COL1A2,NDUFB5,ALB,HDAC5,NEUROD6,ACADSB,MARCHF3,RERG,IKZF5,AP3S2,CTTNBP2,HSPA14,YTHDF2,ANKRD50,GFM2,PSENEN,CYP4F8,RAB1A,G6PC3,ZDHHC8,MXD1,MBL2,VAC14,UGCG,ID4,CLBA1,SYT2,HSP90AA1,LIN7B,CTNNBL1,FOXN2,GNG5,QRSL1,RFC4,MSX2,FAM53B,RHCG,TEDC2,AGER,CDKN2AIP,MYO6,GPM6A,PGM1,EYA3,CX3CR1,JPH4,EI24,AMACR,WDR83,FBXO22,GABBR1,HFE,SNRPE,UBE2E2,EHBP1,CEP85,SAMM50,DPEP3,MRPS26,TWIST2,TFB1M,ARG2,FXN,LRFN3,PROX1,SYVN1,CST11,NEU1,ATP5PF,FLCN,RPP25L,SIAH2,RUVBL2,CCR2,MREG,EIF5A2,KGD4,ISG15,SPTAN1,CHMP1B,ACHE,LTBR,ZBTB16,RLIM,PIGC,B2M,NKIRAS1,HR,MED22,SLC25A10,PACRG,VAPB,RTCB,RGCC,TAS2R16,SRD5A3,GSKIP,HSCB,MIR30B,RBP5,CCNF,TFE3,SLC6A4,MTERF2,RARRES2,LRRTM2,GTF2H5,FURIN,HSP90AB1,ERO1A,MTMR6,TREML1,CAND1,SDCBP,ATP6V1G2,LBH,IFIH1,DCAF16,GSTT1,AIF1,FOXP4,EZH2,PGK1,SPINDOC,PRL,SLC22A17,WDR82,CDC20,LYZL6,YKT6,SLC51A,CCSAP,HACD2,SRP72,PRIM2,CCNA2,POLR1B,UQCC3,TULP3,BORCS6,RPGRIP1L,HP,SYNDIG1,PITHD1,MTPN,HSPB1,TIMM13,GNA14,PCDHB13,SLC35E1,SRPRB,RPL23,NR0B1,HTR5A,GCFC2,DHRS1,SKP1,LDHAL6B,ETFBKMT,PLA2G4B,CGAS,UQCC2,KPNA1,MAEA,COX16,PSMA4,FSTL1,MRPL51,PFDN2,SERINC3,CRYL1,CRTC2,F10,STAT1,RGS10,ETV6,NDST1,SEMG2,GK5,RACGAP1,MEPCE,DHRS3,UBE2K,TRIM34,LSM14A,THAP7,G3BP2,DAPK1,PYROXD2,ASF1A,ACTB,ZNF24,UBIAD1,GABRA1,CABCOCO1,ARF6,SERTAD1,SLPI,PPTC7,PPP1R8,GTF2E1,CLCN6,CYP2C9,MIR145,DNM2,SEMA5A,TOR4A,ELOVL6,CLDN11,RGS19,SLC22A6,PHF12,IGSF11,MORC2,MRPS23,SLC35F1,DAAM1,PRPF18,SLC16A10,ZNF596,PIR,TMEM30A,HTRA1,CDK6,GZMK,FERD3L,MYD88,GDI2,PLCB2,PAX9,GTF2A1,ZBTB45,RERE,NEUROD2,HNMT,CSNK1A1L,BET1L,EFNB1,DCTN3,CYB5R4,HDAC11,FYTTD1,PSMG2,ZNF436,SGIP1,CCDC65,HCFC2,TUBG1,FABP12,SARM1,MEF2A,RMI1,GOSR2,OPHN1,DNAJC7,SFTPA1,MYL12A,TP53INP2,SLC25A32,CD2BP2,SLC35E4,SLU7,AGTRAP,FTL,RC3H2,RNF113A,CD2,UBXN6,CIMIP1,DDIT3,NDST3,NSG1,OPRM1,CD79B,ADH1A,CIART,GCHFR,ZNF790,SERTAD2,TSEN34,NDUFS6,DNAJC2,GPC1,GAS2,FUNDC2,DSTN,NR2F6,RAB14,RBM7,ATXN1L,LAMTOR3,CAPN2,ALG11,CYP2D6,MRPL53,CLN8,ABCF1,SCML1,RPAIN,RDH11,SELL,FAHD1,GFM1,ALKBH4,MRPL11,TRAM2,F9,ICA1,UQCRH,VMO1,GFUS,UBE2D1,BOK,SLAIN2,CLRN1,IFRD1,MED10,CCDC181,TIMM29,H1-5,CHP1,BHLHE40,PPARG,NOA1,OARD1,MYRF,BLVRA,TNFSF10,TES,RAB40AL,PRDX4,CARTPT,CYP2C8,JKAMP,B3GNT2,SOX21,RAB3B,EVA1A,RPRD1A,CLXN,CD274,PRCC,DLST,PSMD14,RBM5,WDR44,TRIM35,TLR2,TMEM14B,DYRK1A,PEX5L,QSER1,PPIH,NLGN2,BTBD10,TCF21,ZNF507,BPIFB4,RBBP7,NUP50,MIA2,E2F6,OSGEP,POLR1D,TMX3,ELP3,MTMR12,SNX1,MBD5,NIF3L1,IREB2,PTS,MME,CD3G,PYDC2,TSSC4,BPGM,NDFIP1,STARD3NL,YIPF3,PSMB11,TLCD4,TECR,TBC1D4,FBXL19,CCDC106,TRIM6,TENT5C,PLAA,GLE1,SELENON,GPRASP2,SSNA1,RPA3,SETD4,CNOT6L,SKIC8,TMSB4X,MAD2L1BP,HBEGF,MGST2,BAD,BARX2,RANBP6,JPT2,EIF4E,FMO1,LURAP1,MATCAP1,LRRC8C,CLP1,RPS15,SYT4,HMGB1,APBB3,SDR16C5,TCP11L2,ZC3H14,COX17,POLR2F,IFT172,CSRNP1,E2F4,PPFIA2,PCCB,PATE4,RETREG2,SYNJ2BP,ESD,CCDC85B,MOSPD1,AP2M1,APEX2,TNNC2,GPX4,MT2A,SPC24,ZNF32,SNAPC2,TXNRD1,MPV17,CTNNB1,CERS6,SNAP23,ATG9A,CXXC1,VEGFC,IRF7,UTP25,RINT1,SRSF4,MCL1,SC5D,ASIC1,ILK,FBXO7,IQSEC1,SNAPIN,CDC37L1,TMEM45B,DDR1,WDR6,UBASH3B,MIR99A,H3C1,ISCU,H2AC13,VPS26C,MORC4,CASP4,SIGLEC5,GJB1,EPCAM,PGAM1,MPDU1,ASCC1,SLA2,SSR3,DHRS7,SUMO2,TOM1,TP53,RPL23A,CTSC,HMGA1,RGS6,KLHL15,STAU1,ASRGL1,RBMX2,GLO1,MYT1L,TIMM8A,RCE1,ZMYND11,RNF8,JCHAIN,SOD1,MAMDC2,STK16,YBEY,IDO1,FOXP3,DGCR6L,PRPF4,NUP62,RPL35,SLC18B1,IRF1,MPV17L2,PDCD4,BECN1,MED30,NME1,CYFIP2,COL3A1,BORCS5,MXI1,VSTM2A,LMO3,MED4,ACKR3,PDYN,KRT8,RPS9,PNPLA4,GNAQ,TCOF1,RPS14,MCMBP,MED27,NUDT19,API5,WBP2,MGST3,ORMDL1,VASH1,THAP2,FBXO11,TBK1,VAMP8,CYGB,SLC25A14,PLN,ODAM,TESPA1,SGF29,APOBEC3B,GSTCD,RPA2,SAYSD1,TMED9,ZBTB26,TMEM231,ACTR3B,SUFU,RING1,FZD6,USP30,EIF3E,SOX14,CCND3,DKC1,DCP2,GJC1,AKR7A2,CSGALNACT2,HDHD3,PAOX,ZNF267,THOC1,KLF3,ZNF609,YIPF5,SLC25A3,MIR194-1,RPS29,PIGK,GIT2,UQCRQ,CDK1,DHRS4L1,FZR1,PSMD6,TBC1D16,GPX3,TRIM24,SNAPC3,KRTAP3-1,MTAP,ZNF304,TFDP2,ABHD16B,SESN2,MACROD1,SVIP,CLCA1,CD63,SLC25A26,THOC3,SEC61B,ATPAF2,MPIG6B,LILRB4,DPPA2,PPM1D,ZNF200,CMTM6,SSBP1,HACD4,CLIC4,KLC2,MVD,STAC3,RNF26,XPO5,CHMP5,CTLA4,RIMOC1,AP5S1,MARCHF5,POLR3H,RALYL,ANAPC15,CNP,PPT1,HS3ST3A1,TCEA1,COMMD3,POLR3B,SNRPA1,ROPN1B,UBE3A,SCPEP1,RAB11B,REEP4,MGAT5B,HSH2D,EMC1,ATP5F1A,GMPPA,PSMD1,CACNG3,FGF13,RAB32,MRPL33,S100A6,RAB6A,TRIM22,LDHB,ACSS2,DERL2,MRPS18C,METTL15,PIGW,TMT1A,RADX,SEC11A,RSAD2,CDC23,DRG1,TNRC6C,THBD,CAB39,REEP6,NEDD8,PABPC1,PHF13,ELOVL3,MDC1,LRRC8D,MOXD1,TCP1,LST1,NRM,PDF,CDKL2,PGAP4,RBM3,TIGD7,CDKN2D,OLA1,FUT8,GABARAPL1,C2CD2,MTRF1,ZNF451,COMT,SYNGR3,SERINC1,RUVBL1,CHTOP,FBXW11,SMAD9,TOR3A,RAP1B,FERMT2,CHPF2,NCKAP1,POLD4,BACE1,TNKS2,MIR208A,IRAK4,CCDC186,MGARP,PSMB4,TMEM39A,LRIF1,UNC119B,TOPBP1,RDH10,ABCE1,FOS,HEXIM1,RFX5,THOC6,USP6NL,RFLNA,GRIK1,STARD13,B4GALT4,VAMP7,GTF3C3,RPL3,SAP30BP,MIR106A,IRF3,AMT,KATNAL1,AATF,AIF1L,HNRNPAB,MAPK10,PHB2,SLC16A1,ZNF787,GLT8D1,OSR2,SPCS3,CYB561D2,PMPCA,PEBP1,CBR3,HEBP2,CRBN,SP2,FTSJ3,H2BC17,NFKBIL1,TMA16,MTG2,PHF23,POLR2B,ARMC7,HYAL2,NEK7,MPHOSPH6,IKZF2,STK38,PKIB,SSH3,TIMM17A,ELOF1,SSBP4,RHOJ,ZKSCAN1,NDUFA2,RPL37A,MTM1,AMELX,HIRA,TAGLN3,PSMC3,TERC,SCNM1,FCN2,SIPA1L1,RUSC2,UBE2L3,VPS26B,DYRK1B,TRIM23,SLC31A1,APOBEC3H,EGLN3,NKX6-2,RPSA,PPP1R26,UTP23,MIR1234,DHX38,MYBL2,VPS26A,SEC61A1,LSM4,H2AC7,SNX24,FMC1,SRARP,CDC7,HNF1B,JUNB,PPP1CC,FAF2,NAA15,SPTSSB,TMEM168,SUPT7L,MIF,RBM42,CCAR2,STIM1,JADE1,LIPA,ATP5F1E,RCCD1,JAML,RPL27,PCYT1B,ANGPTL2,LGALS8,SEC22C,CRLF3,B3GALT2,RRP7A,TAPT1,IDE,IRF2BP1,TAF5L,ADRM1,GDPD3,CINP,CREB1,ANGPT1,GAPDH,FGL2,USP39,DERL1,MND1,EIF1AD,IK,DTL,SGTA,CNPPD1,TMEM160,RIOK2,COX20,SRSF8,FAM193B,THAP1,MRPS18B,PTGDS,IER3,FGF1,GADD45G,NDUFAF4,PLSCR3,BOLA3,ABCB1,HSD17B6,FAM222B,QPCTL,SUCLG2,TMEM190,SMUG1,RPS26,DXO,TRAF6,RPN1,TGFB3,MTHFD2L,CHST10,SRP14,CCNB1,KIN,HOXD12,FOXP1,CAMK2N1,COX7B,SKAP2,PICK1 |
| 2.785e-05 | -10.49 | ATPAF1 (ATP synthase mitochondrial F1 complex assembly factor 1) | protein interactions | 64756 | 126 | 57 | 19454 | 5460 |
RPA2,MTRES1,TOMM22,HSCB,TOMM20,PXMP2,CRYZ,NGRN,RPA3,EXD2,GFM1,AKAP1,FIS1,HTRA2,DNAJC19,MTG2,AUH,PMPCA,MRM2,TUFM,ATP5F1B,SH3BGRL,PARL,TACO1,CCDC90B,RMDN3,PDHA1,PTRH2,GFM2,MRPL11,MTCH2,DDX39A,AURKAIP1,METTL15,FASTKD5,IMMP2L,RIGI,FKBP8,HSPD1,GNA11,HINT2,COX8A,RHOG,TMEM70,MRPS26,MTRF1,GRSF1,SLC25A46,MALSU1,DIRAS3,COX14,MACROD1,AIFM1,SSBP1,YBEY,FAHD1,GATD3 |
| 2.785e-05 | -10.49 | EHBP1 (EH domain binding protein 1) | protein interactions | 23301 | 126 | 57 | 19454 | 5460 |
MGST3,RHOJ,ACAP2,RMDN3,PHF21A,SEC61B,LAMTOR1,RHOB,FIS1,NTRK3,RAB11A,KDM1A,STX7,TOMM20,RHOU,RPA3,RAB9A,DERL1,RAB5A,FGFR1,TOMM22,H1-5,BET1,SEC62,CDC42,EHD1,RND2,HNRNPL,RHOH,STX6,MDM2,CAV1,COX14,RAB35,HRAS,PTPN1,EEF1AKMT3,GJA1,RAC2,RHOG,STYK1,SLC25A46,XPO1,YWHAG,COPS5,YWHAH,KRAS,RAB3B,FLOT1,FKBP8,TMT1A,IGF1R,IFT57,PTRH2,RAB4A,MTCH2,RPAP2 |
| 2.785e-05 | -10.49 | PAK1IP1 (PAK1 interacting protein 1) | protein interactions | 55003 | 126 | 57 | 19454 | 5460 |
LYAR,PLEKHF2,RPS10,SURF6,MDM2,SRSF1,KRR1,RPL8,SRP14,SNRNP70,RPL10A,KPNA1,NOL12,RPS2,IFI16,DDRGK1,HMGN4,KRAS,RPL17,SRSF4,RPL28,PPAN,RPL31,RPL3,RPL23A,RBM34,NUPR1,RPL18,HBP1,RPSA,RAF1,RPL35,RPL13A,ESR2,RPL19,RPL10,SMURF1,PRKRA,RPL37A,FGFBP1,ATG3,SPOP,UBE2H,RIT1,H1-1,RPL7A,CUL3,MYC,ZNF668,RPL4,UFL1,NPM3,DGCR8,UTP23,RPA3,RPA2,RPLP0 |
| 2.785e-05 | -10.49 | TARBP2 (TARBP2 subunit of RISC loading complex) | protein interactions | 6895 | 126 | 57 | 19454 | 5460 |
ILF2,RBPJ,SRP72,DNAJC2,SOX2,EMILIN3,RPL15,STRBP,RAF1,PHF1,RIGI,TGIF2,RPL3,DHX9,PPAN,TCEA2,TCOF1,NKRF,HSPB1,DICER1,MED21,TRAF6,DDX50,CDK9,EGLN3,AKAP17A,RPS16,TOP1,PRNP,HP1BP3,SRPRA,PTP4A2,VAV2,AGO1,TPT1,NF2,HSCB,IRF7,STAU1,RPL4,RNF113A,ZMAT3,MLF1,MYC,CFAP20,CUL3,ESR2,MTM1,KCNIP3,RPL13A,RPP25L,RPL35,SRP54,PRKRA,NUDT18,PSPC1,EIF2AK2 |
| 2.796e-05 | -10.48 | MTMR12 (myotubularin related protein 12) | protein interactions | 54545 | 45 | 26 | 19454 | 5460 |
NDUFS8,NPPC,VIRMA,MTM1,TIMM21,ZDHHC15,CBL,AVL9,YWHAB,YWHAZ,YWHAH,YWHAG,UFD1,SFN,MTMR12,GMPPB,CMAS,RTCB,RPA3,S100B,MTMR2,CYC1,RPA2,VAPB,DUSP1,AKR7A2 |
| 2.819e-05 | -10.48 | SLC1A1 (solute carrier family 1 member 1) | protein interactions | 6505 | 174 | 74 | 19454 | 5460 |
CMTM6,SYNPR,RNF5,TMEM209,PXMP2,DAD1,PIP4P1,RAB29,INPPL1,CXCR4,DERL1,FGFR1,STX17,VAPB,LMNA,TM9SF1,ELOVL1,PRKCA,TIMMDC1,TOMM22,COQ8B,HACD2,YIPF5,SLC25A4,SNX3,NDFIP1,VKORC1L1,FAM210A,DLG4,S1PR4,PTPMT1,GPR89A,SFXN2,CHCHD6,FCER1G,LGALS8,TMEM179B,DNAJC19,VMP1,TM9SF4,RAB11A,FMC1,SLC1A3,ACVR1B,PGAP4,EPHA4,GOLGA7,PSEN1,JAK1,EWSR1,TMEM165,KDELR1,RELL2,AQP3,NRN1,SURF4,DHRS7B,TMEM126A,TUBA1A,YIPF3,ARL6IP5,HNRNPL,SLC25A17,VAMP7,ACSL4,SNX17,SLC35A1,TMEM70,SLC20A1,PEX3,SEC61A2,TSPAN10,TMBIM6,ORMDL3 |
| 2.819e-05 | -10.48 | SCYL2 (SCY1 like pseudokinase 2) | protein interactions | 55681 | 174 | 74 | 19454 | 5460 |
TFRC,CHMP4C,RAB4A,SH3GLB1,KBTBD4,TP53,SOX2,MAP1LC3B,TNF,TRIM37,VDAC1,RAB3B,GARRE1,CDK5,SEPTIN7,HSD17B10,BAG2,RHOG,AK2,FBXO34,MAGOH,LAMP2,ATG9A,EMC4,XPO1,LAMP3,DDRGK1,CNTROB,STX6,POLE3,DIRAS3,CDC5L,RAB35,CD274,ALYREF,PRCC,GJA1,KRT8,CDK1,RPA2,FGFR1,ATG16L1,TOMM22,BET1,UFL1,PFKFB2,STX7,TOMM20,RPA3,SOD1,CRY1,COX17,HSPA8,RAB9A,SQSTM1,AKAP1,RAB5A,LAMTOR1,CHORDC1,PSMD14,RHOB,UBE2H,STK38L,CTSD,RAB11A,SUB1,GORASP2,RHOJ,ESR2,VIRMA,EIF4A3,SMAP2,RMDN3,PTEN |
| 2.819e-05 | -10.48 | SLC16A1 (solute carrier family 16 member 1) | protein interactions | 6566 | 174 | 74 | 19454 | 5460 |
G3BP1,KRAS,SRPRB,DNAJC30,GNG5,GNA11,MAP1B,NDUFA4,NDUFS3,DNAJC2,PDHA1,TUBA1A,LGR4,TP53,CYSTM1,EGLN3,SERINC3,ARF6,BRD9,RAC2,COQ8A,HRAS,RAB35,PHB1,DEGS1,CRBN,YWHAH,ATG7,NGDN,DDRGK1,RAB5C,COIL,STX7,HSPA5,UFL1,KDM1A,STAU1,PRKCB,PMAIP1,AKAP1,ARRDC3,MME,RPA3,UBE2M,RPA2,GRM2,METTL14,RND2,CDC42,CFTR,CDK7,TOMM22,TECR,VIRMA,SEC63,RALA,RHOJ,GNAO1,SEC61A1,PTPMT1,PHF21A,CCNF,VAMP3,LMBR1L,UBE2H,ILK,LAMTOR1,RHOB,DNAJC5,RAB2A,MYC,CUL3,RAB11A,CUL2 |
| 2.819e-05 | -10.48 | PKN2 (protein kinase N2) | protein interactions | 5586 | 174 | 74 | 19454 | 5460 |
EEF1G,STAU1,HSCB,MARS1,TMUB1,RPA3,EP300,THBS3,HDAC5,LSM2,FGFR1,VAPB,RPA2,RARS1,EEF1E1,TANK,RABL3,RPE,TRAM1,RND2,CDC42,RHOJ,VIRMA,JUNB,CCNF,ANAPC2,PTEN,WDR20,RHOB,LSM6,CYP1A1,EIF3G,RIT1,HSP90AA1,SFN,CCNB1,FAM193B,AKT1,MYC,DNAJC5,DNAJC8,BTF3,TGFBR2,CAMKV,KDM4B,LSM4,KRAS,PSMA5,PNMA2,VPS33A,TRMT1L,ATP5PB,TULP3,EEF1A1,SUMO2,RHOH,RPL35A,CEP19,CETN2,CDC5L,ZBTB2,ERLIN1,RAC2,PPM1B,NCK1,RHOG,HSPB1,LSM3,AHSA1,KARS1,UBXN6,PPIB,INSYN1,YWHAG |
| 2.830e-05 | -10.47 | PICALM (phosphatidylinositol binding clathrin assembly protein) | protein interactions | 8301 | 247 | 99 | 19454 | 5460 |
DDIT3,STX7,STXBP1,AP2M1,DOK4,DLST,ATXN1L,APEX1,LAMTOR3,MED17,OST4,PAPOLA,RAB11A,NTRK3,DNAJB6,ILK,VMP1,LAMTOR1,RPS6KA4,RHOB,BRCA1,CYP1A1,MYO6,EWSR1,BAG2,HNRNPA2B1,FLOT1,HNRNPDL,KRAS,SOX2,ISG15,RBM38,RND3,CCR1,CSTPP1,RPN1,GJA1,MAP1LC3A,DNM2,RAB35,DIRAS3,WIF1,XPO1,HNRNPA1,TBC1D5,ATG9A,LAMP2,CBL,DDX1,HNRNPD,STAMBPL1,RHOG,AGR2,RPA3,RHOU,PML,DAD1,ABCC2,HSPA5,SNRNP27,CDC42,POLR1D,ATG16L1,SH3GLB2,RPA2,FGFR1,RTRAF,GSK3A,CCSER2,SMAP2,FERMT2,SMURF1,DYRK1A,RHOJ,CARS1,SEC13,SERPINB1,AP2A1,HAPSTR1,RDH11,SLC25A32,EEF1A1,KBTBD4,CAPZA2,RAC2,ILVBL,CDK9,STX6,ZBTB2,CDC5L,ARF6,PRNP,FCHO2,ST3GAL5,HDAC6,LAMP3,SNAP91,FAM20C,STYK1 |
| 2.838e-05 | -10.47 | RBM48 (RNA binding motif protein 48) | protein interactions | 84060 | 75 | 38 | 19454 | 5460 |
ERH,FAM118B,GADD45G,PNP,TSR2,PAFAH1B3,SCNM1,GYS1,SPRED2,ARMC7,MPHOSPH6,HSPB1,OSGEP,TAF9,FXYD6,GSTO1,RFC5,NTAQ1,ZNF24,GLYAT,TNFSF10,SMN1,MNAT1,KPNA2,CCDC106,RAB27A,SAT1,COX17,CDKN2C,ATPAF2,EIF1AD,ANXA7,CSTPP1,RPA2,MAFG,CDKN1A,PPP1R8,SERPINB9 |
| 2.838e-05 | -10.47 | TXNL4A (thioredoxin like 4A) | protein interactions | 10907 | 75 | 38 | 19454 | 5460 |
SNRPD2,SYNCRIP,CHMP2A,ESR2,RBM42,TOP1,SNRPD3,SNRNP40,SNRPB,EXOC5,TSNAX,ID1,H2AC4,SNRNP70,DDX23,EP300,SF3B1,PRPF4,GRIA2,PQBP1,SNRPA,SSRP1,SNRPG,FBXW7,RBM22,TSSC4,HNRNPF,KRAS,CD2BP2,SNRPN,DDIT4L,SF3A1,ATG16L1,PDE6D,SNRPE,TPD52L1,GSTP1,USP39 |
| 2.841e-05 | -10.47 | response to cocaine | biological process | GO:0042220 | 55 | 31 | 18204 | 5365 |
PPP1R1B,CHRNB2,OXTR,TACR3,SLC1A2,DRD1,HDAC5,CRHBP,SLC1A1,GAD2,MECP2,UBE3A,MYRF,SLC6A3,MDM2,SLC6A4,TIAM1,SLC1A3,CNR1,DRD3,CCNA2,HSP90AA1,OPRK1,HOMER1,GRM2,CDK5,HTR2A,COMT,GRIA1,SLC6A1,ELAVL4 |
| 2.842e-05 | -10.47 | CENPM (centromere protein M) | protein interactions | 79019 | 140 | 62 | 19454 | 5460 |
COPS5,CENPP,PDCD10,DICER1,CENPL,SKIC8,RAP1B,RPRD1A,HRAS,APOO,ANAPC13,PPP2R1A,RBM12,RAP1A,TAF2,GNAZ,VAMP2,NRN1,SKA3,CCNY,NDUFB5,STX8,TMT1A,COPS4,SAR1B,H3C1,CTNNBL1,KRAS,NAA50,RALB,TBCE,GSTK1,RIT1,HTRA2,ZMPSTE24,PCP2,VAMP3,EFHD2,CYB5R3,CYRIB,METAP2,UBTD1,SRC,BUB3,YES1,SNX3,SF3A1,PAFAH1B1,GAMT,MFAP1,ACACA,CTDSP1,PALS2,GNG7,RPRD1B,RAB5A,SNAPC1,SLC39A9,FLYWCH2,YKT6,TRA2B,FBXW7 |
| 2.842e-05 | -10.47 | PPME1 (protein phosphatase methylesterase 1) | protein interactions | 51400 | 140 | 62 | 19454 | 5460 |
PPP4C,PPME1,CAMK1,NHERF1,TMEM165,ACTR2,PPP2R1A,GTF2E2,EEF2,PGAP2,G3BP1,RNASE9,HNRNPF,CSE1L,RUVBL1,ERO1A,PCNA,PDCD10,GSTO1,SSBP4,COPS5,GAPDH,CALR,PDIA3,NFKB1,KARS1,PPP2R5A,ZBTB2,WIF1,PAIP1,XPO5,FBXO32,PPP2CB,FKBP10,RPRD1B,LMNA,RPA2,P3H1,HSP90B1,SNRNP27,MYH1,UNC45A,GON7,HSPA8,LCP1,RPA3,DNAJB6,BRCA1,MCM3,GMPS,CTSD,GFUS,LDHB,TOM1L1,LDHA,PNP,MED17,CMBL,CCNF,SURF2,RAN,CYRIB |
| 2.842e-05 | -10.47 | AGO3 (argonaute RISC catalytic component 3) | protein interactions | 192669 | 140 | 62 | 19454 | 5460 |
STAU1,PHB2,YTHDF1,STK38,FXR2,TOMM20,RPA3,RNF113A,RPA2,EIF4B,WDR77,SPTBN1,CFTR,AGO1,TUBB,TAB1,COPE,VIRMA,PRRC2A,PPP5C,SF3B6,PSPC1,TRIM24,PRMT5,BRCA1,HSP90AA1,CUL3,CEP85,MYC,FBXO7,PRPF31,G3BP1,CNOT7,PTGES3,CNOT6L,LSM14A,PABPC1,GARRE1,RUVBL2,ZC3H7A,TRIM21,TUBB4B,IPO8,TNRC6C,YTHDF2,RAF1,EEF1A1,TUBA1A,SPTAN1,RANGRF,CAND1,HSP90AB1,DBT,FUBP3,DICER1,HNRNPD,ANKMY2,MOV10,CNOT2,QPCTL,CPEB1,XPO1 |
| 2.846e-05 | -10.47 | regulation of biological process | biological process | GO:0050789 | 12079 | 3677 | 18204 | 5365 |
ZMYM6,PGK1,DDAH2,MIR551A,LMO3,TFIP11,CGRRF1,BLOC1S5,SHOC2,RGP1,IRF1,ITM2B,DNAJC5,MKLN1,AFAP1L2,UTP15,ADGRG1,BNIP3L,MIR29A,TAL2,EDC3,MOG,MIR542,CELF6,EXOSC3,SMAD9,SNX17,GNG13,MECP2,NDC80,MIRLET7I,TFPI,OR2A2,PLCB2,ATF4,NOVA1,HNRNPK,ZNF22,PNMA1,XPNPEP1,EXT1,NRDE2,SRC,MIR34C,PSMB4,ZNF609,PPID,MEF2A,PRKRA,MIR135B,TOM1,LGR4,USP30,TMEM117,BIRC5,CAMSAP2,GPR37,DTL,LRRN1,CCL19,MIR378A,ADGRE2,TMEM59,PLAGL1,MIR1180,THBD,CCDC25,NLGN2,POU3F4,OR52W1,AGGF1,CCNF,MIR222,HP1BP3,TESK1,MT1M,LRIF1,ZKSCAN1,NFKB1,WBP1L,LIPT2,EFHD1,CCL4L1,PLP1,SUPT3H,HLF,FBXW4,PSPC1,RPAP2,SOSTDC1,HNRNPF,SYBU,HINT2,ATF3,AKR1B1,ZNF32,MIR653,GFUS,CCDC32,MIR205,SETD5,WDR83,MIR924,PCGF3,KLF10,CRHBP,COL1A2,ESAM,RHBDD3,HNRNPD,EIF4A3,TMEM108,TMIGD3,IRF2BP1,PLP2,SLC7A11,SCML2,SMAD3,ISCU,CD63,DUSP22,CSRNP1,MSX2,INHA,MIR30B,VWF,MIR519D,ABCC2,ZNF280B,ILDR1,POGK,RTN4,MIR548C,RGS10,EXOC1,OLFM3,SNAPIN,MIR593,POU5F1,H3C1,OR51S1,RMND1,LYAR,ELK1,EIF4E3,BCL2A1,VAV2,WSB1,MT1X,IMPA2,FLOT1,OR10G3,GPR37L1,LRRC69,KCNA2,VPS33A,PPP1R17,MORC2,OVGP1,TAS2R13,CPLX3,VDAC1,COPS7A,USP2,SERPINA1,MIR1-2,CFL2,UBB,CAMLG,CXCL9,PEA15,GPR26,UBE2E2,POLR3B,MIR185,ARRDC3,PHF21A,CTDSP1,PLAA,SKP1,OR10P1,DIRAS2,CRKL,MSN,AATF,ODAM,MLLT11,OR4D5,H2AC4,MIR643,GPR160,RAMP3,AKR1A1,PPP1R8,GSK3A,OR1F1,GRID1,G0S2,SSX2IP,ATP8A1,BCL2L1,MAF1,STXBP1,P2RY10,NCALD,PKIB,BST2,GABARAP,PRMT5,H2AC6,KHDC1,LZTFL1,SDHAF2,ISG20,MT1E,MIR9-3,DPH3,LMNA,UBE2V2,MIOS,TBC1D4,STARD13,CRTAP,CTSK,SLC1A2,NPR2,TMEM106A,CCNI,CCL24,GPX1,WDR77,PIK3R3,OR4D6,BOK,LIN7C,SP1,RACGAP1,LIPA,CYP7A1,MIR626,PTGER4,CCNA2,FUNDC2,RPL23,SFRP4,BTG2,RNF20,STK24,PDE9A,RELL2,RHOJ,ESR2,FZD6,FBXO22,EZH1,ITK,OSBPL8,POLR2L,LSM6,TPBG,TGFB1I1,PLPPR1,MIR934,GAPDH,CNOT7,C1QL1,CCL11,SELENOP,PTPN11,FOXI3,AZGP1,CDK6,TRIM27,SLC4A10,DHRS3,ATXN1L,PTPRQ,ACSS2,SGIP1,ICA1,MITF,ZNF451,IL21,CLEC7A,MIR216A,PNOC,SLC39A7,FHIT,PFDN1,BLOC1S2,CD1E,IDO1,TENT5D,CGGBP1,RASGEF1C,GAS2,HSPB8,PSMD14,ACOT8,MIR581,TFDP2,MTRES1,CFTR,DDR1,XAF1,PSME1,NKIRAS2,ANKH,MIR424,LGI1,TRIM23,TNFRSF14,PSMD10,ICOS,ATAD1,JPH4,ZNF622,PREB,S100A10,MIR23A,ZNF304,STXBP6,MAPK10,OR10A6,BATF,YTHDF1,RASSF8,MIR495,OR2A25,MME,CXXC5,ZNF770,INO80C,CNTNAP1,SNX14,MS4A7,MLN,FGF17,ADIPOQ,ROCK2,YAF2,MIR567,ZBTB42,AP2A1,TRIM26,PLPP6,INSYN2A,ARB2A,PPP1R2,MIR208A,IFIH1,ARHGAP19,CRB3,ZMPSTE24,RUNX1,SLPI,ZMYM2,IFT57,MIR421,SNX3,ERLIN1,TAX1BP1,CBFB,CNTROB,MEF2C,KCTD17,MSTN,LYPLAL1,SLC20A1,GPBAR1,ARPC2,PRCC,RC3H2,SOCS4,SMAD5,TGIF2,KDM4B,MAGED2,FGF12,AKIP1,H2AC13,MIR190B,CD83,GATAD1,MARCHF5,KLF9,SAP30BP,MOV10,APLN,CREB1,FRMD8,ANAPC4,SLC20A2,GPR17,MIR556,ZFAND6,APOBEC3G,PTGES,PRDX3,FMO2,DNAJC19,ZNF207,DNAJC30,G3BP1,SPON1,MIR216B,HNRNPA1,WWP2,PRICKLE2,ATP1B1,CSTB,GPX4,NFE2,TADA3,HBP1,CCL21,CTNNA1,BAZ1B,PAGR1,SHC1,PRKCB,TRAF3IP3,ZNF250,NABP1,ATP2B4,MAD2L1,RIT2,MACROH2A1,VPS4B,PIWIL2,TPPP,CCNQ,TOM1L2,MIR940,GREM1,IRF2,RAP2B,TRIM37,NFKBIB,PTPN22,SOX2,PXYLP1,ABHD14B,C1QC,GKAP1,SEC22B,RING1,MIR612,SPRED2,MXD1,PLSCR3,DBNDD1,CRIP1,SRPK2,POLB,SLC6A3,HNRNPH2,ACTA2,SMC4,CRYBA1,METAP1,STMN2,SOX14,SERPINC1,LMBRD2,TNFRSF9,RXFP2,CAMK1,SLC6A6,PIK3R2,KLF1,MIR301B,CCL1,YWHAZ,OSM,AMIGO1,RALGAPA2,CTSA,VRK1,MTA2,CD248,TIMP1,ZNF704,SATB1,NSMCE3,VSTM2L,FGF23,EIF3E,ALPL,CARD19,PPM1B,RRM1,MACO1,BACE1,CD58,THY1,PDE4B,TFEB,TNFAIP8L1,RNF41,SERPINI1,H1-3,CCDC85B,TMEM176B,OLFM2,P2RY12,ROCK1,STX10,SUPT4H1,CTTNBP2,CDSN,MPZ,SYT2,CACNB2,FBXL3,ELOVL3,F7,PIK3CA,CD47,NPY2R,ZC4H2,MAP3K21,SPTAN1,APEX1,RGS7BP,NLGN1,PIAS1,DIRAS1,VAMP3,XRCC5,CYRIB,ACOT13,CDK4,APOBEC3A,C1D,DMPK,MIR373,MYLIP,TACO1,CD1B,ZNF287,SLC12A2,SERTAD3,GNG12,LRRC40,SLC16A10,PSD2,GPR75,IGF2BP1,CLEC9A,PSMC5,DNAJC1,POU1F1,RBM42,CIART,PRDX6,RASL10A,EWSR1,ZDHHC17,NOG,S100A8,APOBEC3C,MIR129-2,SELENOT,MALSU1,TRIM5,PITHD1,CCR4,FAM83A,PROM1,HNRNPL,TXNDC12,BOLL,TRMT112,TRIM32,TMOD3,RAB33A,KBTBD6,MED23,PSMC4,RAB33B,GPR171,DCUN1D5,NAIF1,VSIR,MIR363,OR1M1,CERS2,MIR101-1,NACC2,SFN,DNAJB6,EHD4,AQP11,ZNF507,MIR96,MMP20,MIR648,ATG7,OR2F1,UBA3,ZBTB16,KCNMB2,OCIAD2,SH2D1A,MIR383,RPRM,OPTN,BABAM1,CHMP2B,CDC42EP4,MIR887,TP53INP2,SLC35C1,HHIP,CASP12,PRKAG1,GFPT1,TPPP2,PAX6,OR5A2,MIR577,SAR1B,WNT10B,OR13C8,SPRY1,HAX1,LMNB1,PAFAH1B2,TENT4A,ACTL6A,PPP2CB,FOXP3,MX1,CA2,DRAM1,EIF4E,SDC2,TP53INP1,POPDC2,AHCYL1,CETN2,GADD45G,PADI2,MACIR,LRRTM1,MOSMO,MMP14,PAIP2,HIRA,CCND1,MIRLET7B,SOD1,MIR492,CNR1,XBP1,CD59,INSYN2B,RPL13A,PFDN4,PATE4,GLCE,PRKCE,KRT8,DIO2,ATF1,PARL,LCP1,PIP5K1A,TCEAL1,PPP3R2,TAF11,MIR125A,B4GALT1,RPGRIP1L,PCSK9,MIR187,NYAP2,ACO1,NCR3,CCT7,FKRP,ITGA2,CEBPE,NPY,WNT7A,VSTM2A,ARFGAP1,DELE1,GNRH2,TGFB3,SIAH2,OR4E2,RAB3D,RGS5,TXNRD1,MRGPRX3,VDR,OR10Q1,KICS2,TEF,CXCL11,MIR877,MIR345,OXTR,ZNF688,CLK4,LPAR6,SPRED1,DIO3,PPP1R11,TCF23,FBXO9,SNX18,MYL12B,SIRT7,FAM83C,GRPR,UFL1,CXCL13,RETREG1,SLC15A2,PSME2,CD247,CAP2,TRA2A,CCDC134,TRIM52,ASB7,FOXJ3,HOMER3,PIWIL1,ZNF526,ST7,LRFN3,DROSHA,MIR1249,MIR198,LGALS3,DET1,KPNA2,WDR6,ZNF189,GPM6A,CYP27B1,ZBTB14,ST3GAL4,PAX9,JADE1,CER1,IFI6,MGP,RAB30,TMEM33,ZNHIT3,TIMP4,LILRA3,INTS10,PTPN1,HSPA8,PPIB,KIF3B,SSR1,OR10A7,API5,SDCBP,MIR188,FADS2,SUMO3,OR8B8,MAP1S,TP53,CDK2AP2,RCVRN,FKBPL,CLDN3,CASC3,TAS2R16,CSNK2B,MIR552,PPM1D,RGL1,YWHAB,CASTOR2,NLRP3,CCL25,KCTD9,TPPP3,ILK,RNF152,EID2,GGT7,NLRP2,TENT5C,LSM14A,MIR16-2,CDKN1A,MIR98,HECW1,RNF5,MIR649,PCLAF,GPR15,PKIA,DUSP10,MIR628,GTF2A2,FGF7,RANGRF,DNAJC10,CLDN4,KLHL9,CDK5,FCGR2A,NEK9,MIR624,MID1IP1,ING1,PHB1,HAUS2,ANKRA2,CX3CL1,ATP6V0E1,PPT1,GRM8,MUL1,CBLN2,CCDC186,FAM98A,MIR146A,THAP1,OR5I1,ILF2,MIR504,SWAP70,TADA1,CMA1,LANCL2,MIR150,GPR35,USP5,RUVBL2,DKK3,MIR101-2,GPBP1L1,CSNK1G3,MAP3K12,IRF3,RNF34,KLF12,MIR1225,FBXO8,PARD6A,STK3,IL12A,REN,MIR132,RWDD3,PPP2R5E,SLC6A2,CCL17,MIR302B,GGCT,ZNF652,DUSP19,CRYAB,SECISBP2L,SPEF1,CST3,RORB,AKAP12,DYRK2,DDX42,TLR3,RPS14,UBAC2,MIR3173,SNAI2,MIR489,NAPA,LTBR,EFNB1,ZNF7,CYP1A1,DLG3,DHRS7B,PROK1,HNRNPA0,CPEB1,BAG3,SART3,NDFIP1,CBL,SOX9,RHEB,DRG1,CCR1,TMEM176A,REG1A,CCDC92,MIR558,CD200R1,CYTH2,MIR339,STOML3,CDC5L,ING5,PELO,TRIM29,DNPH1,ANAPC11,CTSB,PPTC7,CCR7,STAT6,RNF8,SETD9,C9orf72,MBD3,HAND2,CFAP20,LCORL,RFC2,CXCR6,CHRAC1,MIR600,RAB1B,TRAFD1,GLRX2,RFLNA,ADD1,SHISA2,SH3BP5L,LSM2,MIR9-1,RPRD1B,OTUD7B,PPFIA2,KLHL15,MYT1L,TOMM7,CCDC3,BORCS5,MIR563,TRNP1,EIF4EBP3,MIR625,GTF2IRD1,TRIM3,TAAR1,GSTO1,MIR549A,DRAP1,TFE3,EI24,SRSF4,LPXN,UBASH3B,COX17,PRMT6,NCDN,MPV17L2,MT1A,TCP11L1,NFE2L2,DNAJB4,EFHC1,SMARCB1,SLITRK1,ZNF175,CBLL1,MCM3,WIF1,CD200,KRIT1,MIR601,POLR2G,KCNJ11,MGARP,MIR765,FAM162A,SST,CALY,STAC3,GNG2,EIF1B,TRIM45,STK16,RNF146,SERINC3,PLCL1,MED17,DOK5,MIR7-3,RAB35,H2AZ2,SFTPD,JPT2,CTLA4,CD2AP,NEK2,PLN,DNAJC7,MARCKSL1,GADD45A,VPS16,UBLCP1,FXR2,CAMK2N2,IL15RA,CRADD,SNAI3,TERT,MIR141,PABPC1,GNA11,ALOX5AP,TFCP2,TASL,PML,NFKBIL1,OR4S2,PKNOX1,RPS7,ADIPOR1,STK38,PSMA1,RINT1,MIR23B,TMIGD1,GNB1,MACROH2A2,CCL23,OTULIN,ANAPC13,TUSC2,MIR920,PIK3AP1,SLITRK2,SERPINB1,CLTRN,OR13A1,CDH8,ALKAL1,NT5C2,STC1,LMBR1L,CRTC2,DHRS4,ANAPC2,WDR82,ELP6,CACNG3,FGFBP1,MIR21,RPS2,CXCL3,COX7A1,DNM2,MIR330,SYNCRIP,MAEA,ELAPOR2,TSPAN17,CREBL2,CD99L2,PROS1,GLIPR2,UBE2B,PMAIP1,BAP1,SLC32A1,RBBP9,HYPK,FERRY3,FGFBP2,LIG3,IREB2,SYN3,FOXD3,PC,MED29,TSPAN18,TTC23,PPP4C,MIR10A,GRM1,GAL3ST4,ZNF263,NEUROD2,RXRG,SNAP91,PPARA,PELI1,TRAF7,VEGFC,PRL,OTX2,NCKIPSD,AURKAIP1,LDLR,TRPC1,KBTBD13,ERP29,MIR633,ABHD6,CSK,ZNF267,BTG1,CRMP1,THRAP3,NPBWR1,LDB2,RNASEL,BRAP,LRRC4,UBE2M,CRISP1,SS18,NUP153,MIR155,ATP5IF1,MIR221,SLC8A1,CARTPT,UBE2N,NCOA5,RIOK2,CDC42EP2,MIR377,CREBZF,TNFSF13,LMO4,GRIA1,RLN2,IL22,TMEM215,TEX261,LACC1,SLC4A8,ABCE1,SMCHD1,MIR500A,FBXL19,MORF4L1,APOC4,LMO2,JAK2,PTEN,TTI2,VLDLR,CAND1,LRP6,MAPK4,LSM4,VPS26A,ASB3,SMAD4,ARHGAP15,SEMA3C,MIR1271,P2RY4,UBE2V1,BRS3,ASZ1,NDNF,SLC1A1,CTNNB1,HYAL2,MIR1227,GPT,COPS7B,CYFIP2,CAMK2G,CD164,PACSIN3,PPARG,CLSTN3,CCDC22,SRARP,UFD1,RABIF,F11R,MIR193A,PRKCQ,SLA2,TMEM237,PGR,RPS20,MIRLET7G,EIF4H,UPF3B,IL3,EZH2,ADCK1,MIR554,CUL2,MNAT1,MIR28,AP1AR,FSTL1,PTGDS,IL34,OR2Y1,CCL8,MIR586,DNAJC2,EYA3,TSHR,NKAP,SRSF1,P2RY1,PSENEN,PRDX2,CHMP1B,NKIRAS1,SCN1B,ITGA6,OR8B12,AZI2,UBE2D3,OR4D2,MIR133B,CCNY,RRAGA,LPAR1,MRGPRX4,ARF1,SVBP,CTSC,RRAS2,PPIH,PIP4K2C,EDEM2,BCL7C,PLSCR1,CDH11,TMEM126A,SLC35B4,LMAN1,BRD3,PRKCA,EIF4E2,RAD23B,TBC1D5,CD1C,NFE2L1,TRA2B,GUCY1B1,VIPR1,CGAS,CTTN,ADNP,RELL1,INPPL1,TBC1D13,DCUN1D1,ELOVL6,GLRA2,TBC1D19,HAPSTR1,SH3GLB1,OR2H2,HNRNPH3,BCCIP,CXCR4,PYCARD,OR2W1,LRRC24,CD226,GABRB3,BCL7B,MAPRE2,HMGB1,CD1D,ZDHHC8,ABHD17A,FEM1A,VPS28,RGS2,MPIG6B,PTK7,CDC42SE2,CXCR1,SSBP4,CDKN2C,CX3CR1,CCM2,PAQR8,RAB11A,PPP1R1B,MAP3K11,DDRGK1,MIR636,NAA15,CRLF3,SLC39A10,CACNB3,MIR611,UBE2I,APOBEC3F,CLDN1,MIR324,ZNF687,ZHX1,PTN,GJC1,TNKS2,GPR22,MTM1,OR10A4,RBM22,CYP2D6,MIR342,SERPINB6,SLC38A3,OR10G7,CNPY4,PIM2,ZYX,NDUFA4,AGAP2,MEPCE,PPP1CB,ADGRL3,SOCS3,RBBP8,PRDX4,MCOLN1,CDIP1,MEAF6,MTG1,BTF3,NFIL3,EED,CTDSP2,GDI2,ZMYM3,MIR105-2,APOBEC3D,DDT,OSR2,CDK1,OR4K2,ATP6AP2,MIR184,ATP1B3,MIR126,CDC20,DAPK1,MIR142,CASK,RIMS3,PREPL,PHF13,DLX1,CSTA,LITAF,PICALM,PYM1,ADAMTS20,TRIM22,FEN1,MTF1,FAM3A,CTNNA2,AIP,ORC5,LTA,CDCA7L,SUMO1,CLRN1,CRHR1,IDH1,SETD3,HNRNPC,RNF126,SMAD1,MIR425,IRF7,RER1,ACTN4,RETREG3,MIR1260B,ZNF177,DDIT4,KLK3,CYTH4,CCL20,JCHAIN,SELENOM,CEACAM5,FABP7,ATP6V1G1,GSTM2,RIT1,CPT2,TF,ADAMTS1,IRF6,PAK1IP1,MBD5,KRAS,DPY30,IL1A,ASB8,H2AJ,STIM1,ISX,NIBAN2,CCNB1,CRYM,GARRE1,RASGRP3,MIR493,BET1L,OR7E24,PCDHB13,PIK3R1,CCDC47,SSRP1,RAPGEF5,SETD4,NR0B1,MIR24-2,KCND3,CPLX1,MAGED4B,FOXP2,MIR30E,NF2,LAMTOR2,CEP85,PRRT1,CCAR1,HSPB6,RPS12,ABHD2,TLR1,IL15,MIR137,MIR298,PPM1G,SIT1,MIR455,ARHGEF6,LLPH,FABP5,SCHIP1,PIK3CG,HNRNPA2B1,FASLG,PMP22,GTF2H2,MIR572,PBLD,IL18,BZW2,TRIM35,WRAP53,SERPINB11,TES,PDCD4,MIR139,CACUL1,STAU1,SESTD1,NEO1,ETV6,PAFAH1B1,SPOPL,WDR12,TIAM1,CDC23,PTHLH,CSNK1A1L,PICK1,AKAP8L,PPIF,CDC42EP3,STAT5A,SNAP23,SGMS2,MRPL12,DUSP9,HNRNPDL,CTNND1,MRPL13,OR7D4,GCHFR,CYP1B1,DCUN1D3,DRD1,PIH1D1,MIR16-1,RDH10,CACNB4,OPRL1,ZNF575,NHERF1,MRTO4,H2AC25,ZNF805,MAPKAPK5,EXOC2,FOXA3,MAGEB1,HDAC6,SGF29,MIR208B,STK11,CREB3,TMED9,CCAR2,MED22,PSMC1,CH25H,ACVR1B,MED10,SAV1,ARFGEF1,OR4K1,TMBIM6,GLUL,VMP1,ASIC1,HR,PRKAB1,NPC2,PTCRA,LACRT,EGLN3,STAR,CMTM7,BIRC2,SLC23A2,YES1,SPTBN1,CD2,NIF3L1,OR5K1,TCEA1,KCTD10,XPO1,SCYL2,PARP2,PRSS8,GRIA2,OCRL,CDKN3,LPCAT3,PPP1R10,LEPROTL1,ORMDL1,TLR9,MIR196B,PPP2R5A,SMG8,MGST2,MIR580,METTL18,UCN,TAPBP,ANXA4,CMKLR2,NCAPG2,GMDS,MAD2L2,IKZF2,MIR423,ZBTB33,FOXS1,DSTYK,MIR130B,IQSEC1,MIR589,SF3B4,GNG5,MIR607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KRBOX4,AREL1,BEX3,BICD2,MIR944,WDR19,BSCL2,CTNNBL1,PRKACB,OR9K2,IL23A,CLK1,VEGFA,FXYD6,SAMHD1,PDE1B,NUDT16,MTPN,PRELID1,UTP25,STX18,MIR939,MIR140,CD40LG,PRDX1,LAMTOR3,KLF3,CSH1,RB1CC1,ASB11,THOC1,LYPD6,GPIHBP1,MIR15A,PHAX,ZFAND2B,TAF1D,NOSIP,TAF10,IL17F,ICAM1,NTF4,RASSF4,TCIM,DPP4,TMEM97,VPS54,TBK1,MIR632,FEZ1,ZBTB39,MIR32,STX6,RAB5A,RARRES2,H2AC1,G6PD,NPSR1,SYPL1,NPPC,CHCHD2,CCL2,PHF23,SEMG2,CLXN,DUSP6,ARL6,JMJD8,EIF5B,ARL2BP,TUBB,PDE2A,OR4K17,FBXW7,LIN7B,TESC,EAF2,PRR5L,STX11,NPY1R,SYK,FGF16,HILPDA,NLRP1,NUF2,RAB14,UBE2L3,GPAM,ZSCAN25,CYB5D2,MAGEA4,MED9,SERTAD1,LAMP3,RASD1,FA2H,RHOBTB1,CNOT6L,APBB3,OR8H3,SYT4,LCP2,SEMA4C,TNIK,UBE2S,TMEM204,SMARCD3,IFNK,GNG10,HDAC3,MIR148A,ZNF24,HP,PNPLA8,NUS1,INSYN1,MIR454,SMYD3,RIGI,SIPA1L1,PEX5L,TXNIP,SNTA1,SNAP29,E2F4,GRAP2,CLIP3,SMARCE1,KLHL25,PPP1R12A,CD274,AKT3,MIR1224,ZBTB2,ZNF581,ID4,NDST1,HAPLN2,PTP4A3,ASPM,BAHD1,GNAO1,CHMP1A,MIEF1,MAGEC2,POLD4,GNRH1,TMEM100,ZNF513,UBE2K,MCM6,TSC22D3,CAAP1,IL2,TRIM63,MIR130A,CYTL1,PAK2,LHFPL4,FCAR,AR,KIF2A,LAT2,MED13L,TERC,BUB3,PID1,CPLX2,PSMA3,MIR450B,RGMA,MIR10B,SMU1,PHC1,ACP5,FGF1,USP46,CCL28,GNB3,NRP1,RPS4X,DUSP26,FUBP3,TMED4,RPL26,GPC1,SLC25A31,SERTAD2,MIR374A,AIFM1,BMP1,GNG3,TCAF2,MAP1B,BAK1,NFKBIA,SAP30,CIBAR1,BRD9,MIR331,ASPA,PIP4P2,GPR34,TAX1BP3,RBM15B,TNNI1,RBM3,CHMP4C,SCFD1,ANGPTL2,TP53TG5,DAAM1,MLC1,S100A6,CDKN1B,MIR218-2,NAA35,MIR193B,CAMKV,FAF1,MIR195,ZNF326,HEXB,MIR335,ZNF692,GABRA2,TRIM15,CEP70,ARHGEF39,MIR147A,CRBN,ZNF790,DLG4,ACKR3,ZNF473,BAG2,TAS2R5,CYRIA,CSRNP3,GNGT2,HPCA,NRGN,MIR1-1,NCBP2,DDX5,GABRA1,HENMT1,TAC1,MDM2,HTR5A,MIR583,ARF6,FUT8,IRF4,H1-5,PDCD1LG2,TENM3,ZBED4,ZHX3,H2AB1,MIR214,MIR502,TMEM107,CCL18,CASP4,RPL6,ZNF655,TAFAZZIN,GNG7,TNFAIP1,ZNF365,GPR89A,NPY5R,WDR44,MIR301A,SUPT5H,PALM2AKAP2,MED4,TOP1,MIR105-1,LRAT,MDFI,KDM2A,OR8G5,CCT8,CHRDL1,STUB1,MIR615,PLAC8,CXCL12,KCNMA1,PNMA2,GOLPH3L,HEXIM2,ANP32A,TESPA1,ERLEC1,RPA2,CAMK2N1,VAPB,NGRN,MIR1298,TBCCD1,NDUFAF2,FXN,SCML1,NKRF,DGCR8,MDC1,CYTH1,TACR1,MIR662,GADD45B,IL4,MIR452,SPIN3,EFNA5,ING2,AP2M1,CHID1,CPTP,CCL27,PDE7A,UST,HEY2,OPRM1,C1QL2,SETD7,ZNF518B,CFL1,RAB9A,HNF1B,MIF,BCL10,ELMOD2,EIF5A2,MIR484,MIR761,FLCN,ARFIP1,FZR1,SOCS2,AGO1,NUPR1,DMTF1,FCHSD2,KCNB1,RGS19,CCL5,CDC16,TRIM68,BRINP3,IFRD1,RBM23,RAB3A,MVD,DCAF5,AZIN1,PAEP,PTPN5,HOXC4,CSNK2A1,GHRL,ERO1A,S1PR4,SYNGR1,SAP30L,IRF8,NUCKS1,SKA3,GRAP,EIF4EBP2,CTTNBP2NL,FKBP1A,PRPF19,DHX15,NR1I2,SEMA5A,SPINK13,REEP6,PRDM4,DDX4,ADRB2,SRSF7,GAS8,RAB3B,SPOCK1,DKK1,VAMP8,MIR367,TMEM182,PKP4,HOXB1,PAOX,GJB2,SESN3,RERE,ZNF596,SCAND1,JAGN1,ALB,DPEP1,PLD3,PARM1,CD209,ZFAND2A,MAP2K3,DUSP3,MIR192,LRP3,TLR8,CIPC,MIR296,NTRK3,ZNF319,MIR618,RFXANK,EIF3K,EIF2B5,MIR153-1,MIR100,BRMS1,LYSET,SLC38A1,LILRA1,SEMA7A,AKR1C2,FBXO7,SOX3,BMPR1A,IVNS1ABP,COTL1,PHB2,TCOF1,MIR148B,SLC25A23,FGL2,TM9SF4,EPS8,LEP,RAB40AL,SQSTM1,COMMD6,MMP28,TNFSF12,NME1,SH3BP4,DAG1,ZNF740,SERPINH1,C1QL3,PIWIL3,SMARCA5,RAB8B,HOXB8,OR5B3,ARHGAP5,MIR34B,GNB1L,DYNLL1,MIR873,GRM2,C2CD2L,TLR5,NINJ1,LAMTOR1,CD38,GSKIP,KCNJ3,ZBTB25,FKTN,TLR10,NDP,EIF2S1,FUT9,CHN2,MIR491,SPATA2,UBXN2B,SRI,FGF13,BMPR1B,DISC1,HCLS1,OR4D9,NKX3-1,GPR85,CLU,CISH,TMEM164,MED30,MINAR1,RAP1A,PNRC1,ELOC,GIT2,DDIT4L,TFRC,NR2F6,PCBD1,SARM1,MAGEB10,KCNJ10,CPNE1,CKS2,ECD,NOS1AP,MOB3C,PCK2,GNAZ,NPB,SMURF1,GNRHR2,EMP2,PEBP1,GPRASP3,NGDN,RHOBTB3,HACD3,JAK1,TPT1,CD36,MIR129-1,SRSF10,GJA10,TCF21,DXO,LGI3,NDUFS3,KCNH1,LDOC1,ARPC3,IFI27,ADCY3,OR4Q3,NEURL2,SERPINB9,LANCL1,ADRB1,EEF1A1,IFNGR1,GPC4,PAK5,MAP4,TRIM34,CD79B,JUNB,MIR186,HAS3,ENO1,GRIK1,USP6NL,DMAP1,STAMBP,SPG21,RFX5,GTF2F1,SLITRK5,YWHAG,FGR,PDE6A,ALCAM,MX2,STK26,PSMC3,RRN3,MIR497,CD14,EIF2AK2,GNAI2,L1CAM,DVL2,CRY1,FGD2,UGCG,DEFB114,RAB27A,TUBA1A,CD34,MED31,MCPH1,IRAK1BP1,STX7,STAT1,USP3,RNF128,GPR146,INO80E,EID2B,CALHM2,MIR578,UBE2G2,TNFSF15,NOP53,SERPIND1,MIR938,SP2,SHLD1,MIR95,TSNAX,KLK5,H2AC7,RALA,CERS6,DR1,SNX5,MIR384,TTL,MAGOH,PDCD10,PRKD3,NAA16,EIF3D,KARS1,DESI1,KCNK10,EMX1,FATE1,MIR30A,PAQR3,GAB1,HECTD1,GABARAPL2,COP1,MIR106A,SESN2,ZNHIT1,FAXDC2,LEMD3,YTHDF2,NFYB,NCSTN,CHRNA7,SERPINA3,NR4A2,ZNF664,EPO,IKBKB,EGR1,MIR422A,CHCHD4,MKKS,TOMM70,SMG9,OR4N2,MIR590,POLE3,DDIT3,PLPP4,MIR340,COMT,RAC2,ADORA3,ADORA1,SIX5,FGF22,AAMDC,MIR770,CYGB,GPR173,ARHGAP21,UBP1,ATG101,RGS1,CXCL8,SKA2,ERCC3,CLIC4,LCMT1,TMEM30A,FKBP8,POMT2,CCR2,F2,CAPN1,NEFL,TBC1D17,RNF144B,H1-6,AZIN2,ACVR1,BHLHA9,ASIC2,ZBTB45,OR4D11,DAP,NUDT3,STRADB,TAS2R46,VAMP2,ZNF593,RFC4,NETO2,HSP90B1,APOBEC3B,USP16,TMEM198,MIR875,GABPA,TRIM46,GTPBP1,HRAS,GPR78,MBL2,DFFA,KCTD11,KLK6,PNMA3,LBX1,NTNG2,RFC5,NKX6-2,TRAF1,TAGLN3,MIR145,ZSCAN5A,DBH,MSX1,PRKX,VAMP7,LY96,RBBP7,MIR505,ZC3H15,POLDIP3,TBC1D1,RAF1,ARMCX3,SRSF2,PTGFR,STN1,MIR640,FERD3L,IL10,ATP1A3,IDE,FAM83B,SNRNP70,CD4,RNF113A,OR4F6,PSEN1,GABRB2,ZNF397,IRF9,SMAD2,BUD31,MIR31,ALKBH5,BRCA1,BLOC1S3,CDKN2D,ODC1,RAB1A,ST3GAL1,OR6M1,SUPT7L,IFNB1,CAV1,TAB1,TNKS,RBFOX2,MIR557,CHRM5,MED21,MTCH2,TNFSF8,CYP26A1,PDCD5,KCNJ2,RPS6KA4,MIR194-1,HTR1F,SNIP1,SSBP1,ZER1,MYC,FBXO11,LY6H,MIR553,SEMA6C,MARS1,MIR490,HSPB1,MIR106B,SLC43A2,FITM2,GPSM3,ITM2A,GLRA1,SOS2,SSBP2,HCRT,LRRC14,PDAP1,ATP1A2,OR10G9,HSPE1,OR2D3,SLC35F6,ARHGAP25,MIR656,OGN,FOSL2,MAP1LC3A,LRP12,COPS5,TWIST2,DIRAS3,OAS1,OR8K1,CHRM1,TTC8,MIR200C,CCT2,H2BC11,NLRP6,CD151,ZSCAN1,OR6C4,CAV2,XPO5,ZBTB26,MIR152,CREBBP,TNFSF18,PROX1,WASF3,ZBTB18,MIR147B,GCLC,WASL,TM4SF20,DYRK1A,FGF10,SPC24,NCK1,DRG2,IL2RG,PPP1R3C,ELK4,OPRK1,TCP1,MIR218-1,ADIG,STOM,OSGIN2,OR8B4,TRUB1,RAN,TRIM10,NR2E1,ZNRF1,CDK17,SBK2,ATP6V1E2,CUL3,RLN3,PSMD1,MIR922,RGS6,MIR652,SLC38A2,CAPZA2,RNF115,MIR874,HIGD2A,OR4A47,MIR769,MIR194-2,AP2S1,RCE1,BCL9,MIR532,GNB4,EID1,CNIH1,REG1B,NECTIN2,VAC14,INSIG2,MIR891B,NEGR1,ELK3,UQCC2,TAS1R2,SURF4,CAMP,MAGOHB,MIR143,NLE1,IFT52,BMERB1,FIG4,TNNT2,CBX7,NTN4,YIPF5,HCAR1,FAM161A,FRS3,P2RY11,EEIG1,RNF10,RNF26,VRTN,NPTX1,VIP,CLEC12B,CCNH,GTDC1,RPS13,MIR183,TLR2,FKBP4,GLRB,CHRM3,TMEM231,IL2RA,CLCN6,MAP2K6,SYP,SYNGR3,MIR7-1,NUP62,EHD3,HPGDS,WBP2,NME2,RGL2,MIR616,POLDIP2,TAS2R7,INTS12,ALKBH4,MIR592,BFAR,NR1I3,DERL2,SCG5,CD40,TNRC6C,PDCD1,ASB1,EGFL7,DUSP1,LHB,SCN3B,ATRAID,WEE2,SLC39A9,SELENON,CDC73,MEF2B,IFNA2,DNAJB2,DNAJC3,FABP4,TNFRSF1B,KCNIP3,PLCB1,PTH2,MIRLET7D,ADM2,MLLT6,E2F6,RPL10,MCL1,LPAR2,GABPB1,VPS18,CNRIP1,CD80,UTS2R,MNS1,DRP2,MED27,GNL1,GTF2A1,CCDC65,SSBP3,GPR65,ZNF576,MIR204,CLEC6A,PLEKHO1,EDNRA,NMI,BVES,PRNP,OXSR1,CARHSP1,TMBIM1,CDC42SE1,DAPK3,CXCL14,PDLIM4,PLXNC1,FOXN2,FUT1,MATR3,TMED1,MIR379,USP38,TOM1L1,AGPAT1,IL6,GNAQ,LSM5,IFNA10,CD86,ZMYM4,ADIPOR2,SOX21,OR5AP2,RAB23,ACSL4,G3BP2,ACVR1C,DNAJC27,MIR223,NKX3-2,DDX1,OR51A4,TBC1D25,PHF1,HNRNPAB,RND2,SIVA1,TOLLIP,EIF4A2,MIR320A,MIR631,MTRNR2L3,SYVN1,CDK5RAP3,EGLN2,ROGDI,PLA2G5,VPS39,B9D1,EIF4B,MIR595,ELAVL4,TAPBPL,SLC45A3,KBTBD2,FAM107A,CLP1,MIR569,DYRK1B,OR4N5,KCND2,IL1B,RBBP4,TNFAIP3,MAX,GID8,MXI1,CREB3L4,PTRH2,HMX2,IGF1,CNOT2,ENY2,UBE2W,ATP6V1G2,NSG1,SV2B,EPCAM,APOBEC3H,HELLS,IMPACT,LHFPL2,MAPRE1,SUV39H1,RHOG,IRAK4,PI16,PSMB9,CCSAP,IFRD2,ATAT1,TCEA2,IPO8,RNF139,HINT1,HMCES,ZNF668,SIAH1,TMEM14A,OR5L1,SEC14L1,LRRC28,CNOT8,MIR99B,ARHGAP1,CHORDC1,MSMP,GABBR1,MIR26B,RAD1,SAP18,CRABP2,CIAO3,OR4M1,RAP2C,EPOP,TNFAIP6,PPP1R1A,SKA1,SOST,SOD2,ASCC1,CNP,OAZ1,MCM4,ACTL6B,CDC26,BRINP1,GNAI3,MAEL,TIFA,FOXC2,NEUROG2,GJA1,CKLF,MIR17,MIR764,CNTN1,RBM38,GPHA2,RAB31,NAB1,CALML5,LRRC4B,SLC25A5,RB1,IK,TNNC2,RIOX2,NFYA,FOLR1,TMSB4X,TMEM39A,SDR16C5,MED11,ELAVL2,EPHB6,ARHGAP12,MIR1296,FBP1,ABHD5,HINFP,ZNF511,TCF19,IL1RAP,TOP2B,CTDSPL2,BCL6,ELMO1,SLC25A4,AVPR1B,MIR191,ATP1A1,ACTB,FGF3,TNF,CAPZA1,RBPJ,SF3B1,NAB2,MIR149,AQP3,CD46,LSM10,IGFBP3,ARPP19,ATP2C1,NLRP9,CD81,TCP11L2,OPHN1,TMEM127,HSPA5,SOCS5,GPR162,LDLRAD4,MYD88,NPTN,H1-10,MAD2L1BP,ANAPC15,VTI1B,TOX4,NCR3LG1,KCNAB1,CLIC2,MIR760,ETFBKMT,CSF2,STOX2,STX8,ATP6V1D,RASL10B,RAB18,TEDC2,TPD52L1,FBXO32,FERMT2,IFT172,RBM12,PTGER2,RCHY1,SFRP1,IGF1R,PLA2G4B,FTH1,ZNF322,ZDHHC15,EFNA3,KCNC1,GBE1,IL2RB,EPHA4,MIR605,PELP1,MIR7-2,BECN1,TOPORS,TNNI3K,FMOD,HBB,DICER1,FIS1,IKZF5,BANF1,DNAJB9,MIR215,CNOT6,IGBP1,IL1R2,SUB1,RGN,MIR429,ANKRD6,MIR936,GNA14,KCNIP2,HGS,PRMT2,HDAC5,MAP2K1,FCGR1A,MIR488,BTG3,TAS2R40,WDR11,SLC38A9,OR51E2,TSN,BUD23,MIR29C,ZBED1,NXPH3,SKAP2,SLMAP,UAP1,THAP7,ISG15,ZNF501,SLC31A1,MSL2,ATP6V1C1,DHX9,SDF2L1,RPA3,BTBD10,SPP1,GJB1,RAB29,GABRG2,EIF2B3,KCNMB1,TRIM8,MIR449B,FRRS1L,PDE1A,RLIM,MIR370,OSBP,HRH2 |
| 2.851e-05 | -10.47 | Influenza A | KEGG pathways | ko05164 | 172 | 85 | 7161 | 2463 |
PIK3R3,NLRP3,MAP2K6,RNASEL,IRF7,PRSS1,DDX39B,TNF,NXT2,HSPA8,PIK3CA,CCL2,IFNA13,IL1B,VDAC1,STAT1,JUN,AKT2,FURIN,EIF2S1,MX1,PRKCB,TICAM1,KPNA1,RIGI,TBK1,PLG,IFNGR1,IL12B,RSAD2,MAP2K3,NFKBIB,IL18,TLR4,IFNAR1,IVNS1ABP,IKBKB,FASLG,MAPK10,CREBBP,OAS1,PIK3R1,IRF9,SOCS3,IRAK4,TLR7,AKT1,KPNA2,JAK2,PIK3R2,DNAJC3,PRKCA,ACTB,CPSF4,PYCARD,IL6,IL1A,MAP2K1,STAT2,CCL5,IFIH1,FAS,NXT1,NFKB1,IFNA10,MYD88,IFNB1,TNFSF10,AKT3,IL12A,EIF2AK2,EP300,IRF3,NFKBIA,CXCL8,PML,RAF1,IFNA2,JAK1,ICAM1,MAVS,TLR3,CXCL10,IFNG,XPO1 |
| 2.851e-05 | -10.47 | Influenza A | KEGG pathways | hsa05164 | 172 | 85 | 7161 | 2463 |
HSPA8,NXT2,CCL2,PIK3CA,TNF,DDX39B,IFNA13,IL1B,MAP2K6,RNASEL,NLRP3,PIK3R3,IRF7,PRSS1,PRKCB,TICAM1,MX1,EIF2S1,PLG,TBK1,KPNA1,RIGI,JUN,AKT2,VDAC1,STAT1,FURIN,IFNAR1,IL18,TLR4,MAPK10,CREBBP,IKBKB,IVNS1ABP,FASLG,IFNGR1,IL12B,NFKBIB,MAP2K3,RSAD2,KPNA2,JAK2,TLR7,IRAK4,AKT1,DNAJC3,PIK3R2,OAS1,SOCS3,PIK3R1,IRF9,IL6,IL1A,PRKCA,CPSF4,PYCARD,ACTB,NFKB1,NXT1,IFNA10,FAS,IFNB1,AKT3,TNFSF10,MYD88,CCL5,MAP2K1,STAT2,IFIH1,CXCL8,RAF1,PML,ICAM1,IFNA2,JAK1,EIF2AK2,EP300,IL12A,IRF3,NFKBIA,IFNG,CXCL10,XPO1,TLR3,MAVS |
| 2.854e-05 | -10.46 | regulation of cell migration involved in sprouting angiogenesis | biological process | GO:0090049 | 82 | 42 | 18204 | 5365 |
NRP1,MIR101-1,SPRED1,MIR188,PDCD10,MIR29C,MIR200C,MIR15A,MIR10B,MIR150,MIR424,VEGFA,MIR126,MIR16-1,MAP3K3,HDAC5,MIR31,MIR885,STARD13,RHOJ,MIR206,AKT3,MIR132,MIR20A,MIR320A,MIR193A,NR2E1,MIR205,MIR495,MIR146A,MIR23A,MIR497,MIR361,FGFBP1,FOXC2,MIR503,MIR221,MIR149,MIR296,FBXW7,MIR10A,KLF4 |
| 2.865e-05 | -10.46 | MED23 (mediator complex subunit 23) | protein interactions | 9439 | 253 | 101 | 19454 | 5460 |
PSMD7,SLC35A1,MED29,MED21,SMAD4,MED27,BRD3,COX5A,EMC4,KARS1,ENY2,HACD3,RB1,CDK8,GINS4,TP53,EXOSC8,CTNNBL1,SNRPG,RNF20,PSMB10,PPP1R12A,ABCE1,RING1,STN1,AP2A1,MED22,ZNF687,CAP2,AR,DYRK1A,ROCK1,PPP1R10,SRP54,SSR1,COX6C,RPA2,MTRES1,WTAP,CNP,CFTR,MED30,FBXL19,FBXW7,KDM1A,POLDIP2,BCL6,PML,RPA3,NR1I3,TCEA1,LCP1,PSMD10,RPL23,VCPIP1,MED4,DYRK1B,ATG7,AGK,PHB1,COPS2,CORO1C,RBPJ,MED9,SPC24,VDR,FOXJ3,TUBA1A,TRIM37,PSMA2,ZNF592,TRIP4,MED10,COX16,RBBP8,GPR17,SCN3B,CREBBP,RFC5,IRF1,PSMD6,MED17,ESR2,GNG12,VDAC2,SEC61B,PHKB,VPS18,CTBP1,MED31,PGRMC1,PPP1CB,STAU1,MED11,TRA2B,EMC1,CMAS,HADHA,MED13L,EP300,ATP5IF1 |
| 2.881e-05 | -10.45 | RNH1 (ribonuclease/angiogenin inhibitor 1) | protein interactions | 6050 | 203 | 84 | 19454 | 5460 |
IFI16,PRDX1,TPM3,DDRGK1,YWHAG,SNRNP70,YWHAB,ALYREF,PPP2CB,LDLR,DSTN,CCAR2,CGAS,RAB1B,RPS10,CEP19,MYL12A,EGLN3,RAF1,PPP2R1A,SOX2,EZH2,PSMC3,NUPR1,HSD17B10,RNASE4,ERO1A,RUVBL2,RPAP3,TRIM37,G3BP1,KRAS,PSMA1,HNRNPF,PTGES3,IMMP2L,RPL17,PSMD12,CUL3,MRM2,SFN,MYC,TNFAIP3,SLC25A1,ST13,PSMD1,PSMD14,TLR9,FAS,SPOP,UBE2H,HOXC4,CDC73,PSMA6,CCNF,SEC61B,PSMC5,PSMD6,ADRM1,NDN,PARL,ESR2,CDC20,UBA52,CFTR,METTL14,LSM2,SDCBP,PSMB7,ADSS2,ACACA,SH3GLB2,SIRT7,PRPF4,RBM23,RPA3,EP300,SMC4,RNASE1,UFL1,HSPA5,G3BP2,PSMC1,POLA2 |
| 2.886e-05 | -10.45 | HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B) | protein interactions | 3182 | 310 | 120 | 19454 | 5460 |
MRPS26,HNRNPD,DROSHA,RHOG,DDRGK1,YWHAG,HNRNPA1,MTRF1,HMGA1,IFI16,CACYBP,HNRNPL,GATD3,EED,IFIT2,PHB1,PDHA1,CHMP4C,EZH2,ACTN4,HNRNPDL,G3BP1,EWSR1,PABPC1,LSM14A,HNRNPA2B1,RPL31,HSPD1,RIT1,HSP90AA1,FBXW11,BRCA1,MRPS25,SNRPB,LDHB,HNRNPC,CUL2,PMPCA,CUL3,MTG2,MYC,AUH,SNRNP40,ACTB,CMTR1,TACO1,PIH1D1,PPT1,MRPS7,PYGB,STAU1,HNRNPA0,UFL1,NUP50,HSPA8,EXD2,SNRPA,NGRN,H2AC4,SNRNP70,CRBN,GAPDH,COPS5,HDAC6,MOV10,GRSF1,TOP1,FZR1,DCUN1D1,CAND1,DLGAP4,UBE2G2,RCHY1,SYNCRIP,SSBP1,NUPR1,ILF2,METTL15,H2AX,DUSP1,MRPL11,UBL4A,RIGI,MDC1,MEPCE,NEDD8,H3C1,HSD17B10,EMC2,SNAP23,DHX9,MRPS18B,FAF1,UBE2H,ELAVL2,PTTG1,IGF2BP1,IVNS1ABP,RC3H2,AR,TUFM,SMURF1,IDE,PTEN,RPS3,CCNF,MTRES1,UBE2M,HEXIM1,METTL14,RPA2,CDC42,ATG16L1,RBFOX2,HSPA5,SQSTM1,GFM1,BAP1,SOD1,RPA3 |
| 2.900e-05 | -10.45 | ACOT7 (acyl-CoA thioesterase 7) | protein interactions | 11332 | 157 | 68 | 19454 | 5460 |
RPA2,LMNA,CRYAB,NCOA5,RPS14,CDC42,SIPA1L1,ETF1,COIL,HSPA5,RNF41,BAP1,SOD1,RPA3,PRDX6,GFM1,SPOP,PKNOX1,BRCA1,TNFAIP8,UBE2H,SORD,KDSR,MYC,ACO2,RETSAT,CUL3,PSMD1,CFL2,ATP5F1A,PSMD4,NDN,RAN,ATXN1L,GANAB,RPN1,EZH2,ITGB5,RAD23B,SRP72,SART3,ATP5PB,YTHDF2,PPIF,THAP1,PSMA1,GUK1,FARSA,OLA1,DUSP19,SAR1B,ENKD1,SFXN1,TCOF1,ABCE1,HSD17B10,UBE3A,RHOG,AK2,NME2,AGR2,PDIA3,KARS1,GAPDH,PPIA,CCT7,CAV1,DSTN |
| 2.906e-05 | -10.45 | ADSL (adenylosuccinate lyase) | protein interactions | 158 | 177 | 75 | 19454 | 5460 |
GNAI3,RAD23B,EIF1AX,VPS33A,TULP3,GTF2E2,MTCH2,CCT5,COMTD1,CTSC,SAR1B,XPNPEP1,PDE12,G3BP1,KRAS,HNRNPA2B1,SFXN1,EHD4,USP15,SSX2IP,DCAF11,MED4,DRG2,FKBP4,CTNNB1,API5,BTF3L4,NT5C2,ATG7,CRIP1,WIF1,CCT7,CNTROB,DERL2,PRNP,TCP1,PAIP1,LCMT1,TYMS,KRR1,OXSR1,RPA2,ADSS2,PTP4A2,RPE,SNRNP27,CCN3,TIMMDC1,G3BP2,MARS1,HSPA5,STAU1,SMC4,GTF2I,YAF2,MAVS,HSPA8,RPA3,SOD1,BMPR1A,DNAJB6,RIT1,ALKBH5,COP1,ATG3,YWHAZ,USP14,MTPN,LDHB,ACO2,SLC25A1,MYC,PPP5C,GPX1,COPE |
| 2.906e-05 | -10.45 | SCAMP1 (secretory carrier membrane protein 1) | protein interactions | 9522 | 177 | 75 | 19454 | 5460 |
KRAS,ARL5B,RAB3B,VAMP8,ARF4,SAR1B,FLOT1,RAB1A,TMT1A,BSCL2,GAD2,SNAP23,UBE3A,TFRC,RAB4A,RPS11,STX12,TP53,SPG21,ARF6,RAB1B,SNAP25,RHOH,PRNP,STX6,DIRAS3,LMAN1,VAMP7,CAV1,RAB11B,HRAS,RAB35,ARL11,HSD17B11,GJA1,RAC2,RHOG,HAX1,STYK1,MOV10,LAMP2,ATG9A,RAB5C,LAMP3,STX7,PIP4P1,RPA3,TSPAN15,RAB9A,ARFIP1,RTN4,RAB5A,RPA2,ARL15,ATG16L1,CDC42,SYNRG,CFTR,RAB14,RHOJ,APEX1,GNB1,VAMP3,CCNF,SCAMP2,LAMTOR1,RHOB,ABCG2,NTRK3,MAPRE1,DNAJB6,TMEM179B,RAB2A,RAB11A,DNAJC5 |
| 2.923e-05 | -10.44 | regulation of amyloid-beta formation | biological process | GO:1902003 | 48 | 28 | 18204 | 5365 |
IGF1,MIR29C,TNF,SPON1,MIR298,EPHA4,MIR24-1,MIR455,MIR339,ROCK2,IFNG,ROCK1,CSNK1E,GSK3A,MIR29A,CHRNA7,LRRTM3,CLU,MIR186,RTN4,MIR206,SP1,PRNP,NTRK2,IFNGR1,PICALM,MIR361,MIR153-1 |
| 2.923e-05 | -10.44 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological process | GO:1903587 | 48 | 28 | 18204 | 5365 |
MIR497,MIR23A,MIR361,FGFBP1,MIR21,MIR146A,APLNR,MIR149,MIR10A,MIRLET7B,MIR503,IL12A,MIR342,MIR132,MIR222,MIR495,MIR193A,MIR424,MIR15A,MIR10B,VEGFA,MIR126,MIR16-1,MIR101-1,MIR24-1,IL12B,MIR29C,PDCD10 |
| 2.934e-05 | -10.44 | CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1) | protein interactions | 54901 | 206 | 85 | 19454 | 5460 |
SYVN1,RAB5A,DERL1,RAB9A,RPA3,PXMP2,STX7,HSCB,RND2,OTULINL,TMEM106A,CDC42,SEC62,ST7,UPRT,LMNA,SSR1,FGFR1,RMDN3,ANAPC2,SEC61B,CCNF,LMBR1L,ESR2,SEC63,TRIM54,TYW3,NAA50,CUL3,GSTK1,CIAO1,RAB11A,NTRK3,FIS1,MAPRE1,LMNB1,TMEM268,IGF1R,CYP2C9,TMT1A,FKBP8,KRAS,RAB3B,DNAJC25,JUN,FAF2,LGR4,TOP3B,STIM1,BPIFB1,RPN1,RAB4A,AQP3,PTRH2,GJA1,RAP1B,HSD17B11,SPINT2,RAC2,PTPN1,DNM2,RAB35,LMAN1,EGLN3,STX6,TMPO,TMEM237,MARCHF4,DNAJC1,ALCAM,ARF6,RHOH,LAMP3,LRRTM1,DDRGK1,DPP4,ATG9A,LAMP2,RAB5C,FAM20C,SLC25A46,HAX1,RNF139,RHOG,ESYT1 |
| 2.947e-05 | -10.43 | nucleobase-containing small molecule metabolic process | biological process | GO:0055086 | 593 | 220 | 18204 | 5365 |
PDE9A,SDHC,RAN,GNPDA1,NQO1,NDUFS6,AK5,LIPA,ELOVL4,SLC52A3,PGK1,GMPPB,APOBEC3H,NUDT7,PAPSS2,NDUFB8,MGAT1,HINT1,NDUFB4,GNPDA2,RRM1,HACD1,GAPDH,NUDT16,HMGCS1,FAR2,CMPK1,SMUG1,AK3,SAMHD1,ATP5F1E,NDUFAB1,NDUFB10,NME1,MTHFD2L,HSPA8,ACSS2,NT5C3A,ATP5MC3,COX11,IDH2,MPP1,UGDH,PDE4B,ENO2,NUDT4,ATP5PB,NMRK1,MACROD1,ELOVL3,GMPS,GNAI3,NDUFS2,ADK,IDO1,OARD1,NDUFV2,PGM1,CNP,CSGALNACT1,DLST,FHIT,TPST1,PDHA1,APOBEC3A,NUDT12,CD38,G6PD,ENTPD4,FUT8,URAD,SDHB,PTHLH,ACOT8,UMPS,BPGM,ACAT1,UGP2,NPPC,CLPX,APOBEC3B,NUDT9,PDE2A,DCTD,ELOVL6,UCK1,GUCY1B1,CACNB4,ATP5F1D,NDUFB5,EXTL2,OGG1,ELOVL1,TYMS,NUDT3,PPAT,EPHA2,NDUFA5,GTPBP1,NME2,ATP5MK,DPAGT1,APOBEC3C,GFUS,SARM1,SHMT1,NT5C2,ERH,PPT1,UCKL1,GPAM,NUDT5,PCK2,GUK1,OGDHL,NDUFC2,MFN1,MTAP,PRPSAP1,MDH1,APOBEC3F,ATP5PO,NUDT1,DTYMK,REXO2,ATP6V1A,ADCY3,PC,ADSS2,GMDS,GFPT1,AK2,ELOVL7,ENTPD3,DCTPP1,DCAKD,NME4,LDHB,NUDT19,ACOT6,NDUFS3,ATP5F1A,PNP,APOBEC3D,NDUFS8,PMM2,DLAT,HTR2A,ENO1,SULT1B1,GNMT,NDUFB7,GNPNAT1,NDUFA12,PDE7A,UCK2,UPRT,GPD2,GLYAT,FITM2,DNAJC30,ACSL4,STOML2,RAB23,FMO2,CASK,HACD2,SUCLG2,MMUT,NUDT18,ALDH1L1,IER3,NDUFB6,ENPP4,CRMP1,APOBEC3G,SLC25A1,ATP5PF,TECR,ATP1B1,TP53I3,DLG1,MVD,RPE,NDUFA2,GLRX,ATP1A2,DNPH1,KDM1A,ADCY2,ATP5MC1,IDH1,ACACA,BAD,DCK,PDE8A,LDHA,NDUFA1,OLA1,QNG1,PGAM1,ABHD14B,FMO1,PDHB,UAP1,FKRP,PFKFB2,SULT1A3,UCP2,UQCC3,PDE1A,RPIA,ATP5MG,KARS1,TTR,ATP5F1B,NPR2,ATP5PD,NUDT2,PRPS1 |
| 2.974e-05 | -10.42 | RNPS1 (RNA binding protein with serine rich domain 1) | protein interactions | 10921 | 408 | 152 | 19454 | 5460 |
HMG20A,WDR44,SRSF10,SNRPA1,RPL7,OCRL,PAIP1,BRD9,SRSF1,MAGOH,YWHAB,RPL23,MED4,RSBN1L,CRTAP,DDX23,DDRGK1,ZNF207,TRA2A,CTNNB1,ZNF345,YWHAG,XPO1,RIOX2,RPL6,PRPF19,SSRP1,GTF3C3,SRSF4,ZBTB14,VDAC1,KRAS,DHX16,SRSF7,PICK1,MKLN1,SART3,CHMP4C,NFKBIL1,EZH2,SUPT5H,DHX38,RAF1,APEX1,ESR2,RPL35,RPS9,SMU1,DLST,HTRA2,RPS5,COP1,LMNB1,CPSF2,SNRPB,RNF40,PRPF31,CFAP20,HNRNPC,CUL2,CUL3,MYC,STX7,SAP18,TRA2B,SRSF2,TSR3,UFL1,EP300,HSPA8,SF3B1,NKAPD1,UPF3B,SNRPA,PYM1,KCTD12,TMEM115,TIMM13,NRDE2,ZC3H14,ZBTB2,AKAP17A,NKAP,MRPL50,TOP1,RPL35A,CAND1,RPL10A,BRD3,AKAP8L,CDK12,SNRNP70,NOS1AP,ZNF473,API5,APOBEC3F,COPS5,CSNK2A1,STX11,RPS13,SCML1,THRAP3,CDC40,CAMKV,HSD17B10,KLHL15,ZC3H11A,RPL3,SNIP1,NUPR1,TAF2,TOPORS,IK,TAF1D,TBK1,DEK,SRPK2,CSTF3,BUB3,TRIM24,SRP54,HEXIM2,CSNK2B,EIF4A3,PPIG,MAPRE1,CASC3,UBE2H,ELAVL2,AP2A1,PIP4K2C,AR,PPP1CC,AATF,RPL4,HMGB1,RPS15,RNF113A,GID8,NLE1,DDX46,DVL2,RPL27,LUC7L3,HEXIM1,RARS1,ZCCHC17,P3H1,LMNA,CDK1,DENND2D,SF3A1 |
| 2.991e-05 | -10.42 | PAIP1 (poly(A) binding protein interacting protein 1) | protein interactions | 10605 | 143 | 63 | 19454 | 5460 |
PABPC1,SNIP1,EMC2,RUVBL2,HNRNPDL,KIF1C,TPD52,TOP3B,PAIP2B,H2AX,PPME1,ILF2,SYNCRIP,PABPC1L,MIF,PRNP,CAND1,HNRNPL,FZR1,NUP35,SRSF10,WWP2,MOV10,APOBEC3F,DDRGK1,TRA2A,TDRD7,SNRNP70,SMAD4,HNRNPD,PPM1G,RPA3,NUBP2,NUP50,SQSTM1,HSPA8,RPS15,WDR77,PABPC5,RBMS2,FTH1,ZNF326,LARP4B,LMNA,NCOA5,LUC7L3,OPTN,CCNF,SF3B4,NDN,IREB2,CUL3,HNRNPC,MYC,FTSJ3,BICD2,ASCC1,EIF3G,CDKN2AIP,CASC3,PDCD4,PAIP2,ELAVL2 |
| 2.991e-05 | -10.42 | DDX41 (DEAD-box helicase 41) | protein interactions | 51428 | 143 | 63 | 19454 | 5460 |
MEPCE,RIGI,PSMA5,KRAS,TRIM26,TRIM37,MAP1B,RPL31,SOX2,RAF1,CDC5L,NKAP,BRMS1L,SIN3A,ANKRD50,BRD3,DDX23,TUBG1,SNRNP70,H2AC4,NOS1AP,CHCHD1,CSNK2A1,YWHAG,HDAC6,DDRGK1,IFI16,MOV10,FAM20C,COIL,UFL1,HSCB,FBXW7,STAU1,EP300,RNF113A,SNRPA,BAP1,DVL2,RPA3,KLC2,HEXIM1,PIH1D1,HECTD1,RPA2,GRM2,CFTR,WDR77,ESR2,SNRNP40,SIAH1,CLVS2,TRIM24,CCNF,EIF4A3,ZNF330,UBE2H,RIT1,RUNX1,SNRPB,CEP70,MYC,CUL3 |
| 3.015e-05 | -10.41 | NUTF2 (nuclear transport factor 2) | protein interactions | 10204 | 118 | 54 | 19454 | 5460 |
HINT1,TAGLN3,TGIF2,PCNA,FKBP2,XPNPEP1,CAMK2G,LASP1,CTNNBL1,KRAS,NUP153,KHDC4,TAF2,NME1,TP53I3,RAB11B,HMG20A,NUP35,EMC6,PGAM1,EMC4,MOV10,SLC35A1,AGR2,YAF2,CCDC106,GPX4,PGK1,FAM50B,RPA3,SOD1,BAP1,MYOZ3,PRCP,NME4,TRA2B,RPE,SUMO1,NUP62,MFAP1,ZNF574,RPRD1B,UBE2I,ZMAT2,RAN,CHCHD3,RPL35,TAGLN2,BTF3,RAB11A,UBE2H,RIT1,AP2A1,PPP1R16A |
| 3.017e-05 | -10.41 | BLTP3B (bridge-like lipid transfer protein family member 3B) | protein interactions | 23074 | 70 | 36 | 19454 | 5460 |
YWHAG,YWHAH,RAB2A,ATG9A,LAMP2,RAB11A,FAM174A,RAB5C,SFN,YWHAB,LAMTOR1,RHOG,YWHAZ,RAB35,STX6,ESR2,DYNLL1,MIF,CDC42,RND2,FNTB,DIO3,ATG16L1,RND3,TFRC,FGFR1,RAB4A,RAB9A,COX8A,RAB5A,RPA3,STX7,ARL6,RAB8B,SCML1,RAB3B |
| 3.017e-05 | -10.41 | NGFR (nerve growth factor receptor) | protein interactions | 4804 | 70 | 36 | 19454 | 5460 |
NFKBIB,NDN,SIAH1,MDM2,CAV1,TRAF1,PRKACB,BFAR,NTF4,UFD1,BEX3,IKBKB,SHC1,TRAF6,NTRK3,IL2,MAGEH1,MYD88,BACE1,SQSTM1,NTRK2,TRA2B,TTR,CD80,TRIM37,NSMCE3,EGR1,BNIP3L,SMN1,TP53,H2AX,TRAF2,CDKN1A,STMN2,TCF19,ANXA7 |
| 3.065e-05 | -10.39 | EMC10 (ER membrane protein complex subunit 10) | protein interactions | 284361 | 50 | 28 | 19454 | 5460 |
CYB5B,EMC9,ST7,OTULINL,DNAJC25,OR4N2,CCDC47,DNAJC22,ADIPOQ,EMC1,GJB1,EMC8,EMC2,TMEM106B,OXTR,ESYT1,CGRRF1,SDF2L1,RHOG,EMC6,SCGB1D1,EMC4,MOV10,SEC63,CCR2,DNAJC1,RAC2,LMBR1L |
| 3.065e-05 | -10.39 | PITPNB (phosphatidylinositol transfer protein beta) | protein interactions | 23760 | 50 | 28 | 19454 | 5460 |
APEX1,NUP35,ESD,TAGLN2,ENO1,GLRX2,HSPB1,OAT,ATG3,ADK,TIA1,ACO2,MOV10,UGP2,PMAIP1,HSD17B10,HSPA8,RPA3,SOD1,HSDL1,PITPNA,DCTD,PRKCA,LMNA,RPA2,LMO4,PGM2L1,ETFB |
| 3.092e-05 | -10.38 | positive regulation of mRNA metabolic process | biological process | GO:1903313 | 231 | 97 | 18204 | 5365 |
MIR106A,MIR342,ALKBH5,MIR625,BTG2,TRA2A,MIR193A,MIR100,DCP2,MIR30B,MIR96,CDC73,MIR146A,MIR519D,METTL14,MIR149,SNRNP70,RBM3,MIR212,MIR181C,MIR423,MIR204,RC3H2,CNOT7,MIR137,EXOSC3,UPF3B,MIR210,YTHDF2,MIR195,MOV10,MIR885,HSPA8,MIR340,CNOT8,MIR26B,MIR190B,MIR140,POLR2G,MIR130B,SF3B4,MIR185,MIR34B,THRAP3,MIR106B,MIR223,MIR135B,NCBP2,AGO1,MIR142,ROCK1,MIR1-1,MIR373,FXR2,MIR206,MIR181D,MIR320A,MIR20A,CIRBP,MIR214,MIR497,CNOT6,MIR130A,MIRLET7C,MIRLET7B,MIR125A,MIR708,PRPF19,MIR200C,MIR424,PABPC1,MIR16-1,TRA2B,MIR491,MIR495,YTHDF1,MIR23A,MIR211,PRDX6,PRMT5,MIR98,EXOSC8,GTPBP1,PRR5L,MIR24-1,WDR77,ROCK2,MIR192,HMX2,CNOT2,PDE12,CNOT6L,MIR9-1,HNRNPD,TNRC6C,MIR145,MIR191 |
| 3.093e-05 | -10.38 | cellular component organization or biogenesis | biological process | GO:0071840 | 5850 | 1840 | 18204 | 5365 |
NUCKS1,SLC66A2,VIPAS39,SKA3,SYNGR1,TAGLN2,CYTH2,ING5,PELO,PRPF19,FKBP1A,EMC1,IFRD1,MTRF1,RAB3A,IMP4,SNAI2,EFNB1,NAPA,LRRC8C,BAG3,ERO1A,SOX9,SART3,VTA1,GHRL,LTO1,LORICRIN,JAGN1,EMC4,LSM2,ADD1,GJB2,RERE,GRXCR1,LRWD1,SYNGR2,PPFIA2,MBD3,MCM8,CFAP20,C9orf72,PRSS1,REEP6,DDX4,ADRB2,ELMO2,ZNHIT6,SF3A1,SEMA5A,RNF8,MAT2A,CCR7,VAMP8,KXD1,RAB1B,H2BW1,DKK1,RFLNA,NAPG,PKP4,GAS8,RFC2,TOMM22,CHRAC1,RAB3B,COG1,GPR35,ING2,EFNA5,AP2M1,SURF6,RUVBL2,SWAP70,CMA1,TMEM11,CPTP,MATN4,CBLN2,FXN,NDUFC2,MDC1,IFT22,NTMT1,CRYAB,AGO1,NUPR1,GGCT,FLCN,DDX42,RPS14,CST3,SPEF1,FAM50B,KCNB1,FCHSD2,SETD7,C1QL2,PARD6A,CFL1,STK3,ZNF518B,HEY2,BCL10,SHPRH,NDUFS8,MIF,TNFAIP1,CD2BP2,SH3GLB2,ZNF365,NUP35,SDHAF1,WDR44,CASP4,RPL6,EID2,ILK,TMEM107,TRAPPC6A,TAFAZZIN,BOLA1,SUPT5H,TOMM20,LSM3,MED4,LSM14A,TOP1,CSNK2B,CLDN3,ARF6,IRF4,H1-5,EXOC3,NLRP3,KCTD9,TPPP3,BOLA3,PPM1D,RP2,COA4,H2AB1,MIR214,MID1IP1,PHB1,RPA2,TESPA1,TEX12,CX3CL1,GINS4,NGRN,NDUFAF2,PPT1,MUL1,CLVS1,VAPB,HAUS2,MYO1B,GTF2A2,CHRDL1,KDM2A,PCLAF,PITPNA,CXCL12,RSL24D1,CLDN4,KCNMA1,CDK5,GOLPH3L,SEC22A,FGF7,RANGRF,LRFN3,CFAP91,HEXB,DROSHA,PIWIL1,ST7,GPM6A,CDAN1,CEP70,SDHAF4,SNX2,CDC123,DET1,GABRA2,BET1,CAP2,DAAM1,CD247,UFL1,RBM15B,CHMP4C,RETREG1,DDX46,FOXJ3,S100A6,TLCD2,OCEL1,RPL35,GABRA1,KIF3B,STARD5,TP53,MAP1S,SDCBP,MDM2,LYZL4,JADE1,IFI6,USP39,DLG4,RBMX2,PTPN1,CYRIA,HSPA8,RAB30,TMEM33,ZNHIT3,TRAM1,RGMA,KRT8,PARL,LCP1,ATF1,SRFBP1,PRKCE,B4GALT1,RPGRIP1L,NRP1,GNB3,PIP5K1A,PHC1,TAF11,SOD1,LHFPL4,AR,REEP4,KIF2A,CNR1,PPFIBP1,HIRA,PAK2,PID1,TUBB4B,NUBP2,RPL27,TERC,MND1,B4GAT1,MAP1B,BAK1,PYROXD2,SNX18,SIRT7,CIBAR1,BRD9,RPL26,ITGA2,SLC25A31,GPC1,FKRP,NYAP2,RPS4X,TMED4,AIFM1,BMP1,SIAH2,TGFB3,NPY,WNT7A,TP53INP2,OPTN,RPL7A,RBIS,OTUD6B,CHMP2B,CDC42EP4,BABAM1,PEX5L,SAR1B,SIPA1L1,CRYZ,TPPP2,SMYD3,PAX6,TNIK,UBE2S,MMP20,AJM1,NACC2,AQP11,EHD4,SEMA4C,DNAJB6,SFN,SYT4,CATSPERZ,FHOD3,ATG7,SMARCD3,HDAC3,ASPM,BAHD1,CETN2,MIEF1,DDX39B,CHMP1A,PADI2,SDC2,TP53INP1,HAPLN2,UTP6,AHCYL1,MCM6,UBE2K,MMP14,MACIR,IMMP2L,LRRTM1,GLTP,POP5,BBS5,BORCS6,TENT4A,SMARCE1,SPRY1,HAX1,SNTA1,CLIP3,SNAP29,E2F4,LMNB1,AKT3,FOXP3,RCL1,ACTL6A,PPP2CB,PPP1R12A,CCDC42,TIMM8B,SPMIP6,LRRC61,ARL6,EIF5B,CBLN4,DCTN6,TRAM1L1,TUBB,NPPC,IGF2BP1,GFOD2,GCFC2,CHCHD2,GLRX5,CCL2,CLXN,CYRIB,XRCC5,ACOT13,FEZ1,DPP4,VAMP3,RPL7L1,TRMT10B,VPS54,PIAS1,H2AC1,RAB5A,TBCEL,SLC12A2,USE1,CENPP,PRPF31,TACO1,C1D,DMPK,APOBEC3A,CLRN2,STX6,MED23,RAB33A,YKT6,RAB33B,RHOBTB1,FA2H,TRIM32,TRMT112,MED9,TMOD3,NAIF1,APEH,UBAP1,RS1,STX11,APOBEC3C,MALSU1,FBXW7,KCTD3,NOG,ZDHHC17,HSCB,NUF2,RAB14,NLRP1,MAK16,OMG,SAMHD1,PPM1K,GTF3C4,SATB1,METTL21A,VRK1,MTA2,BORCS7,VEGFA,MTPN,PRELID1,EIF3E,RRM1,NSMCE3,TMEM170A,RPS11,NDUFB8,BICD2,STMN2,NDUFAF4,DEK,BSCL2,TERB2,AMIGO1,PRKACB,YWHAZ,WDR19,AGK,PIK3R2,CDSN,ROCK1,GFM2,STX10,P2RY12,SUPT4H1,COX20,SPTAN1,ZC4H2,NLGN1,APEX1,NTF4,RAB22A,CACNB2,PIK3CA,TAF10,ARFGAP3,COX14,TRAPPC2L,TFEB,THY1,STX18,PMP2,PARP11,HSD17B8,HIKESHI,UTP25,RPL35A,BACE1,H1-3,NDUFAF6,CHTOP,RB1CC1,SNRPA1,SNRPE,RAP1B,WDR3,PRKCB,NAP1L5,CHGA,SHC1,PLS3,TMOD2,MACROH2A1,NCKAP1,HPS6,MAD2L1,NDUFA2,CHCHD3,ATP1B1,TNR,SPECC1L,CTNNA1,FZD3,BAZ1B,GPX4,CFAP298,CCL21,CIRBP,TADA3,NFE2,SHOC1,EMC2,PCNA,RING1,SEC22B,TGFB2,CHP1,PAK6,SRPK2,REEP3,NOTCH2,PLSCR3,SMC4,KLHL12,SNRPD3,WDCP,FUNDC1,GREM1,FARSA,VPS4B,TPPP,SNX33,FOLR2,PIWIL2,CDH13,TIMM10,EIF3J,PEX13,NPM3,C1QC,TRIM37,NDUFA1,RAP2B,SOX2,LCA5L,MSRB1,CNTROB,KCTD17,CAV3,HSP90AB1,PTPRZ1,FCF1,ARPC2,USP8,VCPKMT,ACHE,CFAP161,ATP6V1A,PFDN6,STARD3NL,EGR2,RPS27L,ARB2A,ATG9A,YBEY,WBP11,SNX3,TAF2,IFT57,CLVS2,IFIH1,NUDT5,ZMPSTE24,SLU7,TDRD7,PRDX3,ZFAND6,SELENOF,TOMM40,SNCB,TMSB10,IER3,TUBA1B,CREB1,G3BP1,ATP6V0B,ZNF207,PEG10,CDK5R1,WDR45,UQCC6,SNAP25,H2AC13,KDM4B,NDUFA12,EIF2S2,USP15,HSP90AA1,INPP5K,CLDN6,GATAD1,TRIM36,PSRC1,LGI1,OGG1,PLEKHJ1,H2AX,PSMG3,RAG1,FBXW11,PPAN,SPHK2,ZNF622,CIDEB,BORCS8,ATG3,PSMD10,PLEKHA8,RPF2,CFDP1,RPS28,DES,UFM1,RHOH,ACOT8,CGGBP1,INA,EXOC5,GAS2,EXOC8,BOLA2B,STK38L,RPS16,LDB1,MTRES1,DDR1,ATL1,H1-1,CNTNAP1,ETF1,TRIM6,SNX14,TMEM106B,CINP,RPS3,CBX5,TRAF2,ROCK2,H2AZ1,PLAAT3,AGER,STXBP6,BRIX1,ZNF304,KATNAL1,RHOB,TAPT1,PLEKHF1,PREB,S100A10,INO80C,STX1A,CORO1C,YTHDF1,RAB32,EZH1,OSBPL8,CHRNB2,MREG,H2BC14,RPS5,CEP41,CAPG,GAPDH,MYRF,CNOT7,CLN8,CNTN2,LSM6,RAD21,TPBG,FUNDC2,CSNK1A1,RPL23,TPM3,RAB39B,YIPF4,RACGAP1,LIPA,CETN3,JUP,STX12,RHOJ,TMOD1,RNF20,RAP2A,TSPO,BTG2,VPS4A,VPS72,MITF,EEF1AKMT3,SRPRB,TAF7,BLOC1S2,DNAAF10,TFPT,UGDH,GHITM,LRRC8A,TRIM27,FKBP10,POLR1B,C1QL1,CEP97,CCL11,HUWE1,PTPN11,HDAC11,PIWIL4,EMP3,FGFR1,ATXN1L,NDUFAB1,BAD,B4GALT7,SSX2IP,FAM91A1,EIF3G,GSK3A,BCL2L1,ATP8A1,LIMS2,STXBP1,RIC3,ATG4C,MSN,CRKL,PHF21A,SKP1,TOR1AIP2,TIMM8A,H2AC4,IZUMO1R,AATF,ENKD1,TMEM126B,IFT25,CCL24,GPX1,CRTAP,RPF1,NPR2,CTSK,SLC1A2,CATIP,WDR77,BOK,HSD17B10,VAMP1,GEMIN8,EP300,UQCC3,VDAC2,CAVIN2,RFC3,AP1M1,RSPH1,ISG20,SDHAF2,PDLIM3,GABARAP,PRMT5,H2AC6,MIOS,STARD13,ZMYND11,LMNA,GMNN,RPLP0,RCBTB1,RMI2,H3C1,SNAPIN,MPHOSPH10,RPL26L1,BCL2A1,AQP2,VAV2,LYAR,CHMP2A,SIN3A,CLDN11,MTG2,CD9,AQP4,EXOC1,MYBL2,LST1,MFN1,TIA1,SEPTIN6,FMC1,NOPCHAP1,RTN4,ILDR1,B9D2,RTKN,PCDH17,CFL2,UBB,CAMLG,COPS7A,RNF14,SNRPB2,KCNF1,MYO6,STOML2,FLOT1,SERPINA5,PALS2,MTA3,WSB1,GNMT,LUC7L3,HSPD1,MRPS7,ROPN1B,CBX3,KCNA2,VPS33A,CHCHD6,MORC2,EFHD1,MRAS,PLP1,KCTD16,IZUMO1,B3GNT2,TESK1,LRIF1,KCNJ8,SYBU,PSPC1,RAB19,NRN1,ESYT1,SYCE3,ARMC1,RNF40,TXNL4A,LRTM2,NLGN2,TRAF6,HP1BP3,ESAM,TAF9,COL1A2,TMEM108,KMT5B,RILPL2,PLSCR4,EIF4A3,TEX19,ISCU,SMAD3,GPAA1,IFIT2,HMGN4,ATG16L1,CDH7,CCDC32,FCGR2B,NDUFA5,FCHO2,UBL4A,PCGF3,KCNG3,SETD5,EDC3,BNIP3L,MIR29A,CELF6,EXOSC3,BMPR2,TOMM6,EMC9,SIGMAR1,MECP2,NDC80,MAIP1,BLOC1S5,NBN,TMED3,ACTR2,NOP16,IFI16,FLRT2,RPS24,ZMYM6,TFIP11,STARD4,AP3S2,PQBP1,RND3,UTP15,MKLN1,ISG20L2,SNCG,KRR1,CORO6,SNX1,USP30,TOM1,PDCL,PRKRA,MEF2A,BIRC5,CAMSAP2,MEIOB,GPR37,STX5,TRIM21,SF3B6,PSEN2,ISCA2,SLC25A46,SRC,PPID,ANGPT1,PTGES3,EXT1,SRGN,MTMR2,NRDE2,FCGR1A,WDR11,RABL2B,STPG4,CFAP61,HDAC5,ACTL9,PRMT2,HGS,KCNIP2,KDM1A,NHP2,MIR29C,BUD23,BANF1,RAB13,SF3B5,UBXN10,DLG1,BECN1,TRAPPC3,SPATA6,DICER1,FIS1,FMOD,CBLN1,ABITRAM,NSA2,RPL7,EXOSC4,FBLN5,GABRG2,RAB29,GJB1,GTF2B,RLIM,OSBP,LCA5,SLC31A1,CXCL1,ZNF501,HCFC2,GINS3,THAP7,RPA3,DHX9,SPP1,ATP6V1C1,RMI1,SPINT2,MSL2,COL3A1,SEPTIN7,VTI1B,RPS9,H1-10,SSH3,KANSL3,FURIN,THG1L,TYROBP,CLDN24,ATP2C1,RPL10L,MYD88,NPTN,HTRA2,OPHN1,TMEM127,H2BC9,CDC42,PPIA,LIMD2,PSMG4,RCHY1,GOSR2,FERMT2,IFT172,CLDN22,IGF1R,EPHA4,IL2RB,PELP1,ZDHHC15,EFNA3,KCNC1,ADD2,NELL2,SRSF12,RNASEK,TLCD1,RFX4,NDUFB7,UNC119B,CDNF,ATP6V1D,STX8,TSSC4,FHL3,MAP1LC3B,RAB18,CCL3,LRRC4B,RB1,LRRC8D,SLC25A5,PRPF18,RAB31,CDK9,TSPYL4,TMSB4X,NDN,DRGX,RBM5,SDR16C5,FOLR1,RIOX2,NEUROG2,CTSD,ALDH1A3,RETREG2,AIF1,TIFA,FOXC2,CNTN1,SNRPD1,GJA1,SEC61A1,MIR17,OIP5,RUVBL1,PDIA3,LRRTM2,SLAIN2,CSRP1,SEC13,SLC25A4,TRAPPC14,CAPZA1,SF3B1,HMGA1,ACTB,PNO1,SHMT1,TNF,PLG,MZB1,IL1RAP,ARHGAP12,EPHB6,TBC1D24,MED11,EMILIN1,CNN3,FITM1,MOBP,RHOU,BCL6,PFDN5,HFE,TOPBP1,ELMO1,NSFL1C,PHACTR1,TOP2B,HMG20A,ATAT1,LHX2,GPHN,GABARAPL1,CCSAP,B2M,APOC2,SIAH1,LUM,SAMM50,S100B,SGTA,SLC16A1,DSTN,SUV39H1,NREP,PPP2R1A,MAPRE1,APOO,TNFAIP8L3,COA5,CHMP5,RHOG,HELLS,KLHL22,IMPACT,CD3G,NEK7,SOD2,PCGF6,MCM4,CSGALNACT1,ASCC1,EHD1,CNP,TNFAIP6,TUBG1,EPOP,SKA1,STK4,VCPIP1,CIAO1,SLC7A9,MAEL,DDX23,ACTL6B,PPFIA3,SDC4,KCTD12,ARF4,TMEM165,RPS15,IMP3,HOMER1,SPTSSB,ZBED3,TMEM14A,TMEM147,PIP4P1,TOR1B,TMED7,LARGE1,LAMB2,CIAO3,RAP2C,GEMIN7,CHORDC1,ANO3,CRABP2,TMEM38B,PCGF2,TRIP4,EMG1,KRT7,CDK5RAP3,CCDC69,FTSJ3,PLA2G5,TFG,KCNS1,TSG101,RND2,HIGD1C,PSMG2,PHF1,MSH6,FAS,KIT,ANP32B,FLRT3,FHIP1B,MT3,NEUROD6,TOX,RBBP4,TNFAIP3,NUDCD3,ABCB1,CALR,NSG1,ATP6V1G2,SKIC8,DKC1,ROMO1,ENY2,UCP2,VPS39,B9D1,CFAP73,METTL15,EXOSC8,PRND,KCND2,AKT1,TAPBPL,ELAVL4,MIR182,ITGB5,SLC6A1,ACP2,FAM107A,CLP1,PPP3CA,DRP2,MED27,MNS1,GTF2A1,NCAPG2,UCN,GABPB1,VPS18,EXOSC1,TAPBP,PLEKHO1,MGME1,CCSER2,EDNRA,MAD2L2,TMEM95,CCDC65,SSBP3,LPCAT3,RBM34,DTD1,SELENON,SLC39A9,OCRL,RPL10,MCL1,MLLT6,ACAA2,ZMYM4,MMP9,CEP19,NOP58,DEGS1,HEXA,BAX,RTP4,IL6,LAMP2,KLHDC8B,DDX1,RAB23,GPM6B,G3BP2,ACVR1C,EMC10,SLX1A,DAPK3,SMN1,FAM149B1,OXSR1,PRNP,SF3B4,IQSEC1,UHMK1,MPV17,TMED1,AKT2,SCLT1,PDLIM4,ATXN10,TMEM231,ATP5F1D,CACNB4,PIH1D1,DRD1,EXOC2,EHD3,NUP62,WBP2,CLCN6,NHERF1,MRTO4,H2AC25,SYP,RNF26,PPIF,CDC42EP3,NPTX1,NTN4,YIPF5,PICK1,AKAP8L,FAM161A,RPS13,TLR2,GLRB,FKBP4,CYP1B1,SNAP23,NPC2,TMA16,HR,MRM2,TIMM13,STAR,VMP1,GLUL,ASIC1,XPO1,KCTD10,WEE2,PARP2,CD2,SPTBN1,SLC2A1,STK11,TMED9,ALKBH4,STX16,MED22,CCAR2,POLDIP2,FOXA3,NOL7,HDAC6,SGF29,MED10,NOC4L,CD40,ARFGEF1,GK2,CAPZA2,NF2,CEP85,PRRT1,AP2S1,EMC8,ARHGEF6,LLPH,RPS12,GTF2E1,HIGD2A,NDUFB4,CCNB1,GORASP2,PCDHB13,BET1L,COX16,H2AJ,TCP1,TIMM21,NIBAN2,STX17,KCND3,MTX2,CCDC47,RAN,NR2E1,SETD4,CUL3,CLDN12,SSRP1,CAMP,ADRM1,SERINC1,WDR55,MIR143,ETV6,GNPAT,CENPW,LYPLA2,SURF4,NEO1,STAU1,CDC23,BMERB1,NDUFS2,NDUFAF3,CBX7,FIG4,NUP107,TNNT2,NLE1,IFT52,PAFAH1B1,TCAP,TIAM1,WDR12,RCCD1,NECTIN2,HNRNPA2B1,FASLG,PMP22,H2BC17,WRAP53,POMP,UQCC2,NEGR1,NDUFB10,NDE1,EEF2KMT,SUMO1,COPS5,CLRN1,METTL25B,HNRNPC,UBN1,SETD3,DIRAS3,MAP1LC3A,LRP12,COIL,KLHL1,ACTN4,RETREG3,CAV2,CCT2,TTC8,NLRP6,H2BC11,RER1,PYM1,PICALM,PTTG1,SLC35F6,ADAMTS20,PRM1,FEN1,CTNNA2,NAP1L3,ARHGAP25,FBXL4,ADAMTS1,TF,CLDN9,NCK1,FGF10,TWNK,ADAMTS10,GTF2H5,KRAS,PAK1IP1,DPY30,STBD1,JCHAIN,CREBBP,PROX1,KCTD15,WASF3,DDIT4,ATP6V1G1,EIF2D,DYRK1A,GCLC,WASL,PLEKHF2,PIM2,ZYX,BLOC1S3,NAA60,TMEM70,AGAP2,RAB1A,TNKS,MEAF6,ADGRL3,MCOLN1,PRDX4,CAV1,PTN,PSEN1,MTM1,GPR22,GJC1,APOBEC3F,ATP1A3,SNRPG,UBE2I,CLDN1,TRAM2,LIX1,BRCA1,ALKBH5,OR10A4,GABRB2,MPHOSPH6,FAF2,CDC20,SEMA6C,GOSR1,MYC,RPL23A,PHF13,CBLN3,FITM2,NAA50,MTCH2,PWP2,ZMYM3,UBE2A,EED,MED21,SNIP1,CDK1,SSBP1,ATP6AP2,RPS6KA4,KCNJ2,TRAPPC13,TFB1M,CTTN,ADNP,ASIC2,SH3GLB1,RFC4,HSP90B1,USP16,INPPL1,KCNA3,DNAL1,VAMP2,PEX3,ZNF593,PLSCR1,BCL7C,HSD17B1,CDH11,TMEM126A,RIMOC1,POMT2,PPIH,AZIN2,EIF4E2,H1-6,TRAPPC10,NEFL,PRKCA,LMAN1,MCMBP,WDR83OS,RAB6B,VAMP7,RAB11A,RFC5,TRAF1,TAGLN3,RAB2A,CX3CR1,MIR145,CCM2,CACNB3,RAF1,ARMCX3,STN1,ATPAF2,DDRGK1,RBBP7,MMP21,PYCARD,BCCIP,CXCR4,TRIM46,EMC6,VPS28,RAB6A,PTK7,H2BC1,NTNG2,GABRB3,HMGB1,BCL7B,MAPRE2,DFFA,KCTD11,PITPNB,ZDHHC8,CHRNA7,ADCK1,UPF3B,EZH2,YTHDF2,COA1,CHCHD4,EGR1,IKBKB,MKKS,FANCG,TRAK2,NR4A2,SRP54,B4GALT6,EMX1,CLSTN3,PRKCQ,SESN2,CALHM3,ZNHIT1,TMEM237,LYRM2,TMED5,GABARAPL2,RABIF,F11R,RANBP10,ARHGAP21,ATG101,SCN1B,ITGA6,COX10,SVBP,BCS1L,ARF1,ERCC3,TMEM30A,NOP9,LPAR1,SKA2,POLE3,DNAJC2,EYA3,TOMM70,DCLRE1C,RRP7A,CHMP1B,SRSF1,TBCE,RAC2,FGD2,UGCG,ACACA,TUBA1A,RAB27A,ABCE1,CD34,SMCHD1,BLCAP,L1CAM,ASF1A,TSR2,CAND1,USP3,STX7,VLDLR,MIS12,FBXL19,MORF4L1,MED31,JAK2,PTEN,MCPH1,LYZL6,RRN3,NUP153,CRISP1,SS18,ATP5IF1,STK26,CREBZF,HPF1,RIOK2,CDC42EP2,GRIA1,LMO4,KLK5,H2AC7,COPS7B,CYFIP2,CTNNB1,SLC1A1,SHLD1,HYAL2,EIF3D,POP7,PACSIN3,RPSA,DR1,PDCD10,TTL,SEMA3C,INO80E,SMAD4,LSM4,ASZ1,PHETA2,NOP53,NDNF,AIF1L,PEX26,SRSF10,GJA10,ARPC3,NDUFS3,BAP1,PMAIP1,CD36,TRAPPC6B,MLH3,TIMM29,NOA1,RPS23,KHDC4,MED29,CKS2,COX7A1,TRAPPC1,CPNE1,KLHL24,POC1B,ANAPC2,NGDN,MAEA,UBE2B,NOS1AP,DNM2,EMP2,SMURF1,GCA,KBTBD13,NDUFB6,SLITRK5,CSK,ALCAM,RPS17,RNASEL,LDB2,LRRC4,SNAP91,TRAF7,MAP4,GPC4,PAK5,NEUROD2,AP1S2,USP6NL,DMAP1,OTX2,TOP3B,HAS3,NCKIPSD,UBXN2B,FGF13,ALOX5AP,NDUFB5,RPL24,EIF2S1,SSNA1,TERT,CBR4,SNRPD2,PML,SRPRA,CFAP97D1,BMPR1B,TASL,HCLS1,DISC1,SLC11A2,NINJ1,C2CD2L,RAB35,UTP23,H2AZ2,TSPO2,GADD45A,MARCKSL1,VPS16,NDP,LAMTOR1,CD2AP,NEK2,TSR3,PLN,TEX264,CLTRN,RAP1A,SLITRK2,KCNJ10,EIF1AX,CRTC2,CDH8,ATG4A,STK38,RPS7,MACROH2A2,MED30,CLU,COX19,TMIGD1,LPXN,TRAPPC4,TMEM199,TFE3,SEMA7A,SLITRK1,EFHC1,SMARCB1,NOB1,MPV17L2,COX17,PRMT6,NCDN,FBXO7,EIF3K,SNX11,ELFN1,RPP25,PET117,BORCS5,TOMM7,LYSET,CLDN8,METTL22,GOLGA5,CHAMP1,TMCC1,RAB8B,TESK2,MED17,SNX10,ARHGAP5,SEC23A,DYNLL1,KRIT1,EPS8,SNRPB,MCM3,TM9SF4,SQSTM1,COTL1,PHB2,IGSF21,DAG1,CALY,SMARCA5,CLDN14,SERPINH1,C1QL3,MMP28,MGARP |
| 3.112e-05 | -10.38 | protein localization to organelle | biological process | GO:0033365 | 752 | 272 | 18204 | 5365 |
DISC1,SPRN,PEX3,RPF2,TOMM20,TIMM23,TRAM1L1,CDKN1A,WBP2,SRPRA,PML,NETO2,NUP62,SH3GLB1,ARL2BP,ARL6,TERT,DRD1,SPCS1,LAMP5,TMEM107,TIMM8B,IK,NUP35,RB1,LGI1,WDR83OS,SEC61A1,BRD3,NDP,DNLZ,H1-5,TRMT10B,VPS54,ARF6,RAB35,NPTX1,XRCC5,SARM1,GRPEL2,UBAP1,DDRGK1,GPAA1,RANBP6,XPO1,MSX1,SRP14,SEC13,LACRT,TIMM13,ING1,RAB11A,RAB33B,RPA2,RAB6B,SEC63,LAMP3,RANGRF,MAPRE2,SYK,CLU,CDK5,RAB6A,TOPBP1,UBL4A,VPS28,EMC6,MACROH2A2,SGF29,SSR3,GRPEL1,STK11,KPNA2,SRP54,FBXO7,SAMM50,SEC62,RAD21,MAIP1,EMC8,EMC9,CHCHD4,TOMM6,SEC61A2,KDELR1,EZH2,IPO8,OSBPL8,SYS1,SPCS2,SRP72,AGK,GABARAPL2,PIK3R1,TSPO,RAN,CCDC47,WDR19,MTX2,PGR,MAPRE1,TOMM7,TIMM21,SCG3,SGTA,PAQR3,NBN,BICD2,RPL23,RRAGA,MDM2,GNPTG,SRPRB,NUP107,FKBP8,SNX10,TMEM30A,SPCS3,TP53,BCS1L,STK4,RAB8B,CHAMP1,EHD1,ZFAND2B,VPS4A,SRGN,MGARP,TRAM1,HSPA8,C1QL3,WRAP53,SH3BP4,RRP7A,CDK20,TOR1B,UTP25,TMEM147,RPAIN,PHB2,HIKESHI,TOMM70,NETO1,SQSTM1,DLG4,DDIT3,INSIG2,ARF4,TSG101,RER1,CSE1L,EDEM1,MCPH1,H2BC11,MACROH2A1,OS9,NRP1,HGS,CHGA,KPNA6,TOMM40L,SUMO1,BCAP29,CPE,TOLLIP,BUB3,CBL,H2AC4,SEC61B,TIMM8A,AIP,SOX9,ARL5B,POLA2,TOR1AIP2,FIS1,SKP1,NUP50,NUP153,BECN1,TOPORS,LMBRD1,LHFPL4,EMC1,ROMO1,NFKBIA,CALR,ZFAND2A,LRWD1,RAB29,TXN,NUDCD3,KDELR2,TNFAIP3,RALA,EMC4,EMC2,KICS2,PPP3CA,FAM53B,PEX26,TOMM22,LMNA,TRIM37,PEX13,NOP53,DHX9,AIFM1,AKT1,TIMM10,ISG15,RNF128,PDIA2,FKRP,TSPAN10,MCM8,PAX6,TIMM29,TXNIP,TNKS,MAVS,PEX5L,TAX1BP1,OPTN,RUVBL2,SUPT7L,SMURF1,TNPO3,FAM53C,HSPA5,RTN4,MDC1,TIA1,TSPAN17,TRAM2,ZBTB16,DNAJB6,CD81,PPP1R10,TULP3,TNKS2,CACNG3,TIMM17A,IMMP2L,ZDHHC15,DNAJC19,KPNA1,DDX1,UBAC2,PMPCA,SEC61G,LAMP2,EFCAB7,TRAF3IP2,BAX,TOMM40,ZFAND6,CAMLG,TNPO2,MARCHF5,ROPN1B,CDK1,HSPD1,HTR2A,HSP90AA1,LMNB1,ATP6V1D,FAM149B1,STK3,EMC10,C1QL2,MTCH2 |
| 3.122e-05 | -10.37 | PTRH2 (peptidyl-tRNA hydrolase 2) | protein interactions | 51651 | 218 | 89 | 19454 | 5460 |
RND2,DUSP22,PGRMC1,VAPB,ATP5PO,TLR5,RAB5A,AKAP1,DUSP9,CXCR4,EXD2,EMC1,UFL1,HSCB,EYA3,GRPR,VEZT,SCFD1,RHOB,MYO6,SEC61B,LMBR1L,ESR2,LAMTOR3,TUBB,ACTB,DNAJC25,YIPF3,RAF1,STBD1,HGS,STIM1,PTRH2,FLOT1,CHCHD2,KRAS,USP30,DDRGK1,RB1CC1,DUSP6,EGLN3,RAMP3,WIF1,LEMD3,JUP,RPA2,MTDH,RTN4,DERL1,MAVS,SQSTM1,RPA3,PHYHIP,ABCC2,TMEM209,RPS15,GPIHBP1,HMOX2,GORASP2,LHFPL6,C9orf72,VAMP5,SYNGR1,CCNF,VIRMA,COPE,RHOJ,CCDC47,CHRM3,CBX3,ATP5PF,ARF4,PDE2A,FKBP8,NUP107,SRPRB,ANKMY2,RPS2,ATP6V1D,MED21,ESYT1,SNRNP70,CDCA3,PTPN1,EHBP1,ATP5PD,CAV1,RPL35A,FZR1 |
| 3.125e-05 | -10.37 | NTAQ1 (N-terminal glutamine amidase 1) | protein interactions | 55093 | 430 | 159 | 19454 | 5460 |
HMG20A,NUP35,NUF2,EGLN3,CGGBP1,KCTD10,SNRPD3,ZNF511,PSMB5,ZNF436,HOMER3,DNM2,PPM1K,NAB2,AGR2,NDC80,PFDN5,SIVA1,MDFI,INPP4A,DCTPP1,VXN,MATN4,SSNA1,ZBED1,HIGD1C,MRFAP1L1,KLHL12,FAM136A,PNMA2,NME1,STMN2,GNG3,TRAF2,CRTC2,PTS,PNMA5,VDR,APEX1,CHCHD3,LRIF1,ACTB,SIAH1,BPIFB3,PGPEP1,SPINDOC,TSN,TAX1BP1,LDB2,PRMT5,KRTAP3-1,PNMA1,ZHX3,HTRA2,SLC15A2,LSM14B,S100A11,PLEKHJ1,RBBP8,SLPI,ISCA2,THAP7,LIN7B,SFN,MTG2,LMO2,FTL,ATP6V1G1,SAP18,COIL,BOLA2B,LZTFL1,DNAL4,CCDC184,SAT1,TIFA,BIRC2,RABAC1,TRIM5,MTHFD2L,NCOA5,RTF2,GSTO2,THAP6,CTBP1,MRPL12,BORCS6,LMO3,BEND5,LNX2,SPDYE4,ZBTB2,MALSU1,TNR,GSTA4,GNPTG,MIF,KCTD15,MIOS,SELENOV,ETV6,TSNAX,SSX2IP,MSMB,CENPP,GNMT,SMN1,STX11,RPIA,PPP1R27,TOLLIP,HSPE1,THG1L,SIKE1,MYD88,VAC14,GNPDA2,ACOT13,GPX7,EXOSC8,THAP1,EMILIN3,SNAP29,TRAF1,GMDS,JAKMIP2,PYGM,KCTD9,TRIM54,TRIM24,TRIM27,CSNK2B,INPP5K,REEP6,CCHCR1,STN1,TRIM23,ARFGAP3,PCBD1,CEP70,NTAQ1,CEP85,MED22,DHPS,LRRC73,CSK,TRIM32,TICAM2,TNFAIP1,LSM12,CDR2,SH3GLB2,ZCCHC17,PAK5,JUP,LMNA,FTH1,NDUFAB1,KCNH1 |
| 3.154e-05 | -10.36 | cytosolic small ribosomal subunit | cellular component | GO:0022627 | 44 | 26 | 19108 | 5553 |
RPSA,RPS14,RPS20,RPS27L,RPS12,EIF2D,RPS16,RPS23,RPS28,UBA52,RPS4X,RPS10,RPS26,FAU,RPS2,RPS7,RPS11,RPS24,RPS13,RPS29,RPS17,RPS15,RPS5,RPS27A,RPS3,RPS9 |
| 3.201e-05 | -10.35 | PLEKHA5 (pleckstrin homology domain containing A5) | protein interactions | 54477 | 224 | 91 | 19454 | 5460 |
CCDC92,PROM1,MAP4,STYK1,HRAS,EIF4E2,RAC2,ARF6,KCTD3,STX6,EPHB6,CAV1,IGF1R,LSM4,SRSF12,CDC16,CIAO1,DNAJC5,RC3H2,SH3BP5L,ANAPC4,MAPRE1,CTNNA1,GSK3A,RHOJ,DYRK1A,SRPK2,VIRMA,SPTBN1,RPS14,CDC42,SIPA1L1,FGFR1,TRIM36,AGAP1,DVL2,RHOU,RAB9A,KDM1A,PPP2R5A,XPO1,YWHAG,YWHAH,CTNNB1,RHOG,CDC23,CAMSAP2,YWHAB,RAB35,PPP2CB,WDR82,GJA1,KRT8,RHOH,SPTAN1,EGLN3,DIRAS3,MAX,PPP2R1A,KIF2A,PNMA2,RAB4A,RND3,RHOBTB1,SLC25A5,MRFAP1L1,ZYX,FHL3,TESK2,KRAS,LAMB2,FLOT1,MYC,RAB11A,SFN,LAMTOR1,YWHAZ,RHOB,COP1,NTRK3,PHF21A,FBXO22,ESR2,DES,GINM1,RND2,RTKN,CCDC186,TRIM52,STX7,FTL |
| 3.220e-05 | -10.34 | HTR1B (5-hydroxytryptamine receptor 1B) | protein interactions | 3351 | 60 | 32 | 19454 | 5460 |
TMEM87A,HTR1A,CERS2,ATP5F1D,RER1,GALNT2,SYNGR2,ATP5PB,FAM234A,FUT8,ATP5PO,CD209,SIGMAR1,GOLGA5,ELOVL1,FAM3C,GXYLT1,MPDU1,SCAMP2,RMDN3,RETREG3,XXYLT1,ATP5F1B,VKORC1L1,ATP5PD,MSMO1,KDSR,MDFI,GSTK1,ATP5F1A,FAM20B,NME2 |
| 3.226e-05 | -10.34 | IDH2 (isocitrate dehydrogenase (NADP(+)) 2) | protein interactions | 3418 | 189 | 79 | 19454 | 5460 |
ARCN1,GSTP1,ACAA2,RNF103,RPA2,CDK1,CFTR,MRPL12,IDH3B,NDUFAB1,TIMMDC1,SF3A1,LAP3,SLC15A1,ADRB2,HSCB,UFL1,RNF5,EIF5B,PRDX6,TXNL1,IDH3A,RPA3,PTRHD1,BAP1,SLC39A9,DNAJB6,FXN,OSGEP,ICAM1,NAPA,USP14,FBXO7,PMPCA,RAB11A,ACO2,CLIC4,SNRPB2,CDC20,LGALS3,CTSB,ACAT1,ENO1,IRF2,CCNF,SOD2,CCR1,PDHA1,CAPZA2,EZH2,PGM1,GNPNAT1,HADH,ACTN4,GLRX5,TGFBR2,CD80,IDH1,HINT2,TRIM21,AGPAT1,TST,RB1CC1,SMCHD1,AGR2,RHOG,ZNF207,LYPLAL1,DDRGK1,PDIA3,G6PD,WIF1,PRNP,GATD3,FAHD1,NRSN1,DSTN,UBE2N,AIFM1 |
| 3.236e-05 | -10.34 | POLR3B (RNA polymerase III subunit B) | protein interactions | 55703 | 121 | 55 | 19454 | 5460 |
POLR2L,RPRD1A,POLR2I,POLR3F,NOB1,ASNSD1,EMC4,MOV10,ATG9A,POLR3GL,CSNK2A1,BRD3,MED4,PSME1,RPAP3,DNAAF10,CTNNBL1,KRAS,PTGES3,PDRG1,GTF3C3,TP53,TRMT1L,EEF1A1,RPAP2,APOBEC3D,POLR2C,POLR2G,POLR2D,RBPJ,POLR2F,POLR3H,GSK3A,POLR3B,MATR3,POLR2B,DSN1,MYC,SMARCA5,PPP1CC,UBE2H,RIT1,POLR1B,MAF1,PFDN6,PFDN2,RPA3,P4HA2,MRPL17,POLR1H,TPT1,POLR1D,RPA2,RPRD1B,PIH1D1 |
| 3.239e-05 | -10.34 | TBL2 (transducin beta like 2) | protein interactions | 26608 | 166 | 71 | 19454 | 5460 |
CCNF,MRPL53,LMBR1L,DPEP1,GSK3A,SF3B4,PRKRA,RMDN3,SEC61B,FBXO22,CHCHD3,RPL10,SEC63,SUGP1,ATF4,CUL3,CIAO1,BTF3,RBM27,SERPINH1,RPA3,TEX264,TSPAN15,MTDH,EP300,RNF113A,PMAIP1,RTN4,UFL1,NF2,BCL6,ATG16L1,OTULINL,FAXC,SEC62,ST7,LMNA,RPA2,GRM2,SSR1,FGFR1,RPLP0,SPINT2,RAC2,DNAJC1,FZR1,TOP1,RAMP3,WIF1,ZBTB2,NUP35,PTPN5,WWP2,FAM20C,HDAC6,COPS5,DDRGK1,SNRNP70,ESYT1,MAP1B,TSPAN17,EMC2,KRAS,RIGI,B3GNT2,CCDC47,NDUFA2,SOX2,ISG15,LGR4,SOD2 |
| 3.264e-05 | -10.33 | peroxidase activity | molecular function | GO:0004601 | 57 | 32 | 18094 | 5411 |
HBE1,GPX2,SELENOF,PRDX1,PRDX4,GSTM2,IPCEF1,GSTT1,HBA1,GPX5,GPX3,MGST2,HBM,TXNRD1,SESN2,CYGB,PRDX6,TXNDC17,PRDX3,GSTA1,GPX1,GPX6,GSTK1,HBB,GPX7,GSTP1,MGST3,GPX4,PTGES,PRDX2,ALOX5AP,CLIC2 |
| 3.278e-05 | -10.33 | regulation of immune response | biological process | GO:0050776 | 944 | 334 | 18204 | 5365 |
IL15,HMCES,TICAM1,NFE2L2,TLR1,LGALS3,CNOT7,TRIM15,IKBKB,RBCK1,B2M,YTHDF2,IL23A,LILRA1,MOG,LPXN,EXOSC3,ATAT1,EIF2B2,ITK,RNF115,SAMHD1,CD3G,UFD1,PIK3R1,ZNRF1,YWHAZ,IRAK4,IRF1,TRIM3,PQBP1,PRKCQ,SLA2,SLC15A2,PPARG,TLR8,IFI16,LIPA,FCMR,CXCL13,CD247,EIF2B5,BPIFB1,CSNK1A1,PIK3CA,CD47,IL17F,IFNG,SPPL3,CD1E,IDO1,IL21,CLEC7A,LGR4,MIR34A,NEK7,IL18,PLPP4,PSMB4,HSPA8,LILRA3,SRC,PTPN1,PTPN11,FGL2,TOMM70,MICB,PHB2,HEXIM1,LEP,SQSTM1,TRIM27,TLR4,THY1,CD200,SEC14L1,PDE4B,NECTIN2,CD1A,NONO,TRIM21,MIR140,PSPC1,LSM14A,TNFRSF14,TASL,INPPL1,MAP2K6,MIR105-1,SPHK2,KCNJ8,CACNB4,NFKB1,ARG2,NPY5R,CGAS,CLEC12B,MIR17,CD2AP,CD38,CD1B,CD1C,TLR10,TICAM2,TRAF6,EIF4E2,NLRP3,TLR2,IRF4,TIFA,CCR2,TLR5,CCL19,TMEM126A,MAPKAPK3,CTLA4,NINJ1,XRCC5,PLSCR1,TBK1,CYRIB,VSIR,SARM1,TNF,IL10,DUSP22,MUL1,XCL1,SMAD3,SLC39A10,CACNB3,TRAF2,PIK3AP1,KMT5B,PDCD1,FCGR2A,TESPA1,KLRC2,TRIM32,TRIM6,LY96,RPS3,PHB1,BIRC2,TFRC,YES1,TRIM62,MBL2,ABHD17A,NLRP1,HMGB1,SYK,CD1D,CLU,CD40,OTULIN,HFE,BCL6,FCGR2B,S100A8,NFKBIL1,MAPK10,DUSP10,PSMA1,CD226,TRIM5,BATF,STAP1,HRAS,PYCARD,AGER,STK11,IFNB1,TRIM11,CAV1,CPTP,SIN3A,RIGI,TYROBP,NCR3LG1,MAD2L2,LYAR,NMI,RC3H2,VAV2,FURIN,TAB1,MAVS,CLEC6A,SERPINB9,CD36,CD28,TAX1BP1,CD80,POLR3F,LYPLAL1,MEF2C,GFI1,SOCS5,IL20RB,RTN4,TNFRSF1B,IFIH1,IFNK,TLR9,SH2D1A,RGCC,IL4,MYD88,SFN,LCP2,MIR149,LILRA2,CD46,CD81,LILRB4,MIR146A,PSEN1,IFNA2,CD4,MIR21,STOML2,CCL5,FOXP1,FCER1G,IL12B,LRRC14,FGR,UBE2K,ELF1,POLR3B,TLR3,CSK,RSAD2,IL6,BAX,USP38,SPG21,GPR17,CD86,PYDC2,SASH3,CD79B,JUNB,LILRB1,MATR3,CD274,FOXP3,IL12A,HSPD1,BCL10,HSP90AA1,IRF3,USP15,IL6ST,PRNP,BTN2A2,FLOT1,RNF34,PELI1,JAK2,FKBP1A,NLRP6,IRF7,TLR7,CD200R1,MIR200C,MIR708,PLA2G5,TIRAP,STX7,NR1H2,PRKCB,PRKCE,LACC1,LTA,FOSL2,TRAF3IP3,OAS1,FCGR1A,MIR20A,XBP1,CD59,HCST,TNFSF13,NDFIP1,STAT2,KIT,EIF2AK2,FAM3A,CD14,IL2,PAK2,IFI35,BECN1,CRKL,CNR1,LAT2,FCAR,KLRD1,BANF1,UBE2N,EP300,NFKBIA,KARS1,PIANP,FCN2,CLPB,DUSP3,TGFB2,RAB29,SHLD1,TNFAIP3,GPX1,EIF2B3,KLK5,COL3A1,PTPN22,MIR136,IL1B,C1QC,DHX9,NOP53,AKT1,TRAFD1,CCR7,TLR6,STAT6,ISG15,KLK3,NCR3,SELENOS,HCFC2,CREBBP |
| 3.280e-05 | -10.33 | DPF2 (double PHD fingers 2) | protein interactions | 5977 | 332 | 127 | 19454 | 5460 |
TXNDC12,DEK,PSPC1,CCNF,METAP2,TUBA1B,PHAX,MACROH2A1,ZNF655,SMARCA5,CDC16,CARS1,RPL26,RUNX1,AR,LDOC1,MBD3,SS18,BRIX1,BANF1,PRKCB,LCP1,RPRD1B,RPA2,ZNF326,HBB,HSP90B1,H2AC7,PAX9,KLF4,LUC7L3,CAPN1,POLR1D,FZR1,PRNP,TOP1,CDK9,MYL12A,DBT,H2AZ1,CHID1,SNRNP70,ID1,BRD3,NFKB1,IRF4,COPS5,PPIL4,HDAC6,H3C1,IMP4,OLA1,ARF4,CAPZA1,TFRC,ACOT13,RAP1A,H2AX,EGR2,SOX9,MRPL23,TAGLN2,ACTB,RBBP4,ESR2,ARF1,MRPL13,CIRBP,MYC,HNF1B,COPS7A,HNRNPC,CUL3,HNRNPAB,IRF1,SMARCE1,MCM3,PCCB,CMAS,EEIG2,SMARCD3,FOS,SF3B1,DDX5,DDIT3,PPARG,ELF5,MYL6,ACTL6A,RAB6A,COPS7B,INA,FUBP3,RPLP2,BRD9,DDX1,HNRNPD,LHX2,VPS26A,MRPS35,WWP2,BCL7C,ACTL6B,RAP2B,PSMA1,EMC8,LASP1,ETFA,MCM6,SSRP1,PAX6,COPS4,BCL7B,SCYL2,RINT1,PICK1,FAM76B,PDIA6,EZH2,SF3B5,POLR2C,SMARCB1,MTA2,GFPT1,NCSTN,H1-3,SOX2 |
| 3.296e-05 | -10.32 | regulation of growth | biological process | GO:0040008 | 603 | 223 | 18204 | 5365 |
TNR,ADRB3,GHRL,CSNK2A1,EXOSC4,SOD1,IFRD1,RND2,AR,CRKL,GAMT,IL2,PLAA,BST2,NRP1,DNPH1,ING5,BCL2L1,RASGRP2,PTEN,TSG101,RGMA,IGFBP4,FOSL2,L1CAM,EGLN2,PRKCB,GSK3A,LRP12,AKT1,SPOCK1,SPP1,MIR25,FAM107A,PROX1,MT1E,GREM1,SERTAD2,ADRB2,SMAD4,SEMA5A,AGR2,TGFB2,IGF1,MBD5,DIO3,SLC6A3,TTL,MT3,GH1,MAP1B,HYAL2,BRCA1,PLCB1,MIR208A,HTRA2,DNM2,ZMPSTE24,RTN4,RUNX1,HDAC3,MIR548C,SMURF1,DNAJB2,HBEGF,CDC73,MTM1,FXN,IGFBP3,ANAPC2,SYT4,SFN,MIR204,FOXS1,MEAF6,MAD2L2,SIN3A,RERG,MEF2C,EFNA5,NDUFS3,CAV3,MSTN,CDKN2AIP,BAP1,CDKN2D,VGLL4,UCN,ENO1,CDK1,FRZB,SASH3,PSRC1,HNF1B,PPARA,STK3,PAK5,TMEM196,MT1X,HEY2,ADRB1,MMP14,FOXP1,BTG1,CDC42,CRYAB,SOCS2,CREB1,SFRP1,G6PD,MIR222,GJA1,CD38,LAMTOR1,DDR1,STAT5A,MT2A,TMEM97,FOXC2,F2,VPS54,SPHK2,PML,CDKN1A,NPPC,PSMD10,DUSP6,DISC1,LGI1,ADNP,FGF13,CTTN,RB1,MT1M,DCUN1D3,SERTAD3,BCL6,CXCL12,SAV1,PLAC8,ACVR1B,DERL2,CISH,MINAR1,CDK5,RGS2,NPY1R,STK11,DUSP10,ADIPOR1,CCAR2,CXCR4,EAF2,NOG,S100A8,FBP1,TRIM46,HDAC6,SMAD3,PPT1,MUL1,RBPJ,PARP2,NAIF1,DCUN1D5,CRLF3,RBBP7,RAB33B,TFRC,SLC23A2,PHB1,ING1,WNT2,TRIM32,CCN3,GPAM,CDKN2C,MSX1,PRKCQ,SESN2,PPP2R1A,PI16,KLHL22,CDKN1B,OSGIN2,TP53TG5,CGRRF1,CLSTN3,BMPR1A,CYP27B1,MTPN,MKKS,MECP2,MT1A,SLC6A4,IL7,LAMTOR2,BMPR2,ESR2,EI24,SEMA7A,VEGFA,SH3BP4,GHR,PPIB,FGFR1,CRABP2,CSH1,CCDC85B,JADE1,LEP,SELENOP,TOMM70,MIR590,STK4,TP53,MAEL,SDCBP,PAFAH1B1,MIR873,PIK3CA,SYT2,MIR1-1 |
| 3.302e-05 | -10.32 | NGRN (neugrin, neurite outgrowth associated) | protein interactions | 51335 | 233 | 94 | 19454 | 5460 |
ETFB,RAF1,NDUFS6,PDHA1,NDUFA12,RBM3,PPAN,RPL31,SRSF7,COX8A,KGD4,ETFA,NUP42,HNRNPDL,MRPS17,SRSF4,RPL6,MRPS35,CLPX,TRA2A,MRPL9,NDUFV2,HNRNPA1,MRPL18,MRPS26,RPL7,HNRNPL,NDUFS8,NDUFAF3,MRPL12,MRPS18A,NDUFA5,GTF2H5,MRPL57,NOP53,NDUFS2,TRA2B,MRPS7,HNRNPAB,PYCR1,HNRNPC,AUH,MYC,MRPL16,MRPS25,FBXW11,CIRBP,MCAT,DLST,TACO1,MRPL13,MRPL23,NDUFAF4,MRPL47,NDUFA2,MRPL11,STRBP,NDUFS3,MRPL49,MRPL51,MRPL52,MRPS18B,MRPS33,MRPS18C,MRPL22,GRSF1,MRPS9,SSBP1,PRR3,RAP1B,MRPL50,MRPL24,MRPS23,RBM42,RBMS2,MRPL10,MRPS34,MTRES1,DCTD,ZNF574,DLAT,GFM1,TWNK,MRPL41,MRPL40,NME4,MRPL17,MRPL20,POLDIP2,PYCR2,RPL26,MRPS16,MRPL53,MRPS28 |
| 3.304e-05 | -10.32 | PDCD5 (programmed cell death 5) | protein interactions | 9141 | 78 | 39 | 19454 | 5460 |
CDC42,TUBA1A,NUDT3,RAF1,TP53,CCT5,MOB3C,LMNA,RPA2,TUBB4B,SAMM50,CASTOR2,PICK1,YAF2,ACP5,RPA3,BAP1,CCT8,BCKDK,KRAS,KDM1A,UBE2D3,EEF1G,STAU1,ATP1B1,UBE2H,CCT2,TUBG1,CCNF,TUBA1B,EEF1AKMT3,MDM2,LRIF1,CCT7,CETN2,TCEAL1,FZR1,TRIM35,PRNP |
| 3.348e-05 | -10.30 | PPA1 (inorganic pyrophosphatase 1) | protein interactions | 5464 | 169 | 72 | 19454 | 5460 |
SUCLG2,DDAH2,VIRMA,NDN,PRDX2,MCPH1,CCNF,RAN,NRP1,CDC73,UBE2H,BRCA1,RHOB,ATP5F1A,CFL2,TUFM,GMPS,MYC,CUL3,PMPCA,HNRNPC,PTPN11,BCL6,STAU1,GPC1,HSPA8,NMRAL1,PMAIP1,LCA5,SOD1,RPA3,BAP1,RHOU,HEXIM1,GSTP1,UBE2M,PIH1D1,LMNA,RND2,CDC42,PRDX3,CFTR,PCK2,NPC2,SPPL3,PRNP,RHOH,RAC2,CD274,AIP,UBE2N,HSPB1,GSTO1,AGR2,COPS5,GLO1,PDIA3,SAR1B,KRAS,HSPD1,RHOBTB1,FURIN,PLS3,CBX3,CHMP4C,EEF1A1,CCS,EEF2,GGCT,RAF1,TP53,E2F4 |
| 3.348e-05 | -10.30 | CUL9 (cullin 9) | protein interactions | 23113 | 169 | 72 | 19454 | 5460 |
UBE2E2,MRPS35,CSNK2A1,MUL1,EIF5A2,ESYT1,SHC1,TGFB2,CDC23,FAM222A,DOK6,UBE2G2,EEF1AKMT3,PSMB1,TTC9C,TOP3B,TP53,SOX2,DDX39A,NUP153,ZNF397,RAB6B,ITGB5,CASK,AP2S1,BIRC5,SCYL2,HNRNPA2B1,DHX9,NEDD8,PSMA1,MRPS33,VDAC1,PRELP,GTF3C3,CDC16,CUL3,HNRNPC,HMGCS1,H2BC9,MRPS16,TEX19,ANAPC4,GTPBP2,GAB1,VDAC2,EIF4A3,APEX2,MRPS28,FAM83B,ANAPC2,SNRNP40,UBE2L3,UBB,SH3BP4,NCKAP1,AGO1,UBE2F,RNF7,ISOC1,ZNF770,MYL6,SLC25A3,SIRT7,CLK1,DLAT,MTDH,HADHA,SRSF2,PFKFB2,ITGAV,SKP1 |
| 3.360e-05 | -10.30 | Antigen processing: Ubiquitination & Proteasome degradation | REACTOME pathways | R-HSA-983168 | 311 | 131 | 10285 | 3229 |
SOCS3,AREL1,DET1,TRIM21,KLHL25,PSMA5,UBE2H,HUWE1,SIAH1,FBXW4,RNF115,ANAPC13,PSMB3,ASB7,KLHL3,RBCK1,TRIM37,RCHY1,PSMD10,FBXL3,HECTD3,FBXL19,FBXO9,KBTBD13,UBE2S,ASB1,ATG7,UBA52,SPSB1,FBXO30,RNF144B,PSMC1,CUL3,UBE2N,FBXL4,ASB3,UBE2V1,RNF14,ZNRF1,CCNF,SMURF1,PSMA6,UBE2K,FBXO7,PSMB2,PSMD1,CDC23,PSMB4,ANAPC4,SEM1,PSMA1,UBE2D3,KLHL22,PSMC3,ANAPC11,FBXO31,PSMD4,UBE2E2,RPS27A,PSMB1,TRIM63,TRIM32,CDC20,FBXO32,PSMB7,MYLIP,CDC16,PSMD3,PSMC4,PSMA3,PSMB5,PSMB10,PSMC5,PSMB11,UBE2W,PSMA4,ZBTB16,RNF34,FBXW11,PSMB6,PSMA2,UBE3A,UBE2E3,PSME1,UBE2B,UBA3,SKP1,ASB8,FBXL7,CUL2,TRAF7,PSMD7,ASB11,ELOC,SIAH2,TRIM11,UBE2A,HECTD1,UBE2G2,PSMD14,UBE2L3,UBB,UBE2F,CDC26,HERC3,PSMD12,KLHL9,WWP1,UBE2V2,HERC4,FBXO22,TRIM36,PSMD6,ANAPC2,PSME2,UBE2D1,STUB1,RNF41,FBXW7,RNF126,WSB1,FZR1,PSMB9,KBTBD6,RNF182,FBXL14,UBE2M,UFL1,FBXO44,RNF7,RLIM |
| 3.369e-05 | -10.30 | RFC5 (replication factor C subunit 5) | protein interactions | 5985 | 195 | 81 | 19454 | 5460 |
RPA2,MED23,HEXIM1,MED31,DDIT4L,PSMC4,ATG16L1,CCND1,CFTR,LMO3,HSCB,UFL1,FBXW7,NUCKS1,POLA2,COIL,RPA3,CD40,RFC4,BIRC2,NMRAL1,RC3H2,COP1,ZBTB38,RIT1,UBE2H,MYC,CUL3,BTF3,DAPK1,TRIM29,FBXO22,RPL35,LRIF1,RPL10,ESR2,VDAC2,CCNF,ZNF330,PTEN,MTMR2,RAD1,NUPR1,RNF8,EEF1A1,SOX2,EXOSC8,H3C1,HUWE1,KRAS,MEPCE,MDC1,SSRP1,RFC3,RFC2,RPAP3,RUVBL2,PCNA,H2AC4,SNRNP70,HAX1,NAB2,TSNAX,BRD3,DRG1,UBXN6,HMGA1,WWP2,XAF1,DDRGK1,CAND1,FZR1,TOP1,SUMO2,EGLN3,CDC5L,GTF2B,H2AZ1,PHB1,EED,RB1 |
| 3.392e-05 | -10.29 | ASL (argininosuccinate lyase) | protein interactions | 435 | 27 | 18 | 19454 | 5460 |
FBP1,RAF1,NTAQ1,BAG3,TUFM,GINS4,PDHA1,CBL,NCDN,ACOX1,TRIM3,CLK1,OVGP1,ARPC2,NEDD8,MCMBP,APEX1,SRPK2 |
| 3.400e-05 | -10.29 | regulation of viral genome replication | biological process | GO:0045069 | 85 | 43 | 18204 | 5365 |
APOBEC3F,PPIH,IFI16,APOBEC3H,PLSCR1,BANF1,SLPI,IFIH1,APOBEC3A,HACD3,EIF2AK2,CD28,OAS1,PABPC1,IFNB1,APOBEC3B,CNOT7,BST2,TMEM39A,MAVS,ISG15,ISG20,APOBEC3C,PROX1,APOBEC3D,MORC2,TOP2B,PPID,INPP5K,MX1,STAU1,RSAD2,TRIM6,APOBEC3G,PDE12,PPIA,DDX5,CXCL8,VAPB,TNF,CCL5,SRPK2,RNASEL |
| 3.413e-05 | -10.29 | RNA polymerase II-specific DNA-binding transcription factor binding | molecular function | GO:0061629 | 342 | 137 | 18094 | 5411 |
TADA3,SMARCD3,WBP2,HMGA1,COMMD6,DDRGK1,PHB2,FOXP1,CALR,GTF2I,CSNK2B,DDIT3,DDX5,HAND2,HIRA,KLF4,C1D,WWP2,NFKBIA,SIN3A,SMAD2,E4F1,NIF3L1,PPID,NR1H2,FBP1,ZNHIT3,KDM1A,PRMT2,DMAP1,PPARG,FOS,TCF21,TCF23,HEY2,POU1F1,ANXA4,TP53,CRKL,NR0B1,LMO2,TAF10,MED17,LDB1,HMGB1,SDR16C5,CTBP1,MTA2,TRIM68,SETD3,CTNNB1,MED4,DHX9,FOXP3,MEF2C,NR1I2,CREBBP,SMAD4,JUN,CDK5RAP3,TRIM24,PSMA6,TRIP4,HDAC3,BHLHE40,TTC8,SMAD3,HCLS1,EGR2,H2BC9,ELK1,ATF4,YWHAH,GTF2A2,PPARA,CD34,SMARCE1,STAT1,DUSP26,MED30,RNF14,NR4A2,TRIM32,LRIF1,SMARCB1,SRC,TGFB1I1,MTDH,SP1,NOTCH2,GTF2B,CREB1,TAF7,HSPB1,PROX1,FKBP4,RERG,CPNE1,VDR,ID4,RAD23B,RBBP8,THRAP3,CRY1,MKKS,TRIB1,BUD31,BBS5,ACTN4,FAF1,PADI2,BCL10,STK4,JUP,RBPJ,PAGR1,ADD1,AR,RB1,GTF2A1,NKX3-1,MAD2L2,MEF2A,GABARAPL1,TOB2,SRARP,HDAC5,PRKCB,NFE2L2,BRMS1,PSMD10,PCNA,EP300,ACTB,TAF11,IFI27,AIP |
| 3.415e-05 | -10.28 | KEAP1 (kelch like ECH associated protein 1) | protein interactions | 9817 | 311 | 120 | 19454 | 5460 |
MED4,DCAF11,PSMD10,IKBKB,UBE2D1,STK4,XPO1,IFIH1,STK3,HSP90AB1,EGLN3,TRIM15,MAP1LC3A,WDR82,KLHL12,PRKAG1,EEF2,NFE2L1,DIPK1A,GABARAPL1,MED9,RAF1,UBE2A,CDK20,TRIM37,RBBP7,KLHL1,HSP90AA1,ICAM1,COP1,SP1,BRCA1,DCAF4,FBXW11,ELMO2,BAG3,MCM3,IRF1,CUL3,CUL2,NIBAN2,ESR2,MAD2L1,PAQR4,SYNE4,TAX1BP1,SNRNP40,PSMD4,SSH3,POLR2F,PHF21A,RRAS2,BAD,ARCN1,ETF1,KLHL3,MCMBP,STAU1,NUP50,EP300,DDIT3,HSPA8,TMEM160,USP15,LSM3,IL17F,SMCHD1,TUBG1,GAPDH,GPRASP2,CSNK2A1,FAM20C,CAV1,RB1,CDK6,LDLR,SESN2,NFE2L2,PIK3CA,ENC1,SOX9,MAP1LC3B,GLRX5,RIGI,FKRP,TOLLIP,KLHL24,PTTG1,ATRAID,KPNA6,NTAQ1,CCNB1,CIAO1,NUDT4,ASTN1,DYRK1A,PRKCE,GABPA,SGTA,GSK3A,EZH1,CTTN,OPTN,CCNF,BORCS8,GABARAPL2,CCND1,PAQR3,SNRPN,WDR83,ATG16L1,GABARAP,TUSC2,CLU,TSPAN5,KDM1A,SQSTM1,KLHL28,SYVN1,BAP1 |
| 3.430e-05 | -10.28 | ATM (ATM serine/threonine kinase) | protein interactions | 472 | 308 | 119 | 19454 | 5460 |
SIRT7,NBN,PML,AATF,ATG16L1,TPT1,EEF1E1,HCST,RPA2,LMNA,UTP15,PRKCA,DYRK2,CREB1,DCLRE1C,CTTN,AMIGO1,ODR4,PTEN,ALB,TXN,NREP,VIRMA,SMARCA5,GMNN,PPP1CC,SPOP,TDP1,STK11,SPSB1,HUWE1,H3C1,CD80,POLL,RNF20,ZNF821,RIGI,MSH6,EIF3E,MDC1,MTA3,TP53,H2AX,NFE2L2,ACVR1,IK,VAC14,CD274,NHEJ1,DCK,NAT2,TOP1,CDK9,MDM2,CD99L2,EDEM1,COPS5,HDAC6,E4F1,BCL10,DNAJC7,KPNA1,TOPBP1,CXCR4,XRCC5,HSPA8,RAP2A,UCHL3,NPTN,NOP53,STAU1,FAM234A,NPY2R,CDKN1A,ZER1,SCN2B,MCPH1,TRIM29,FBXO22,APLNR,APEX1,ESR2,OPRM1,GPR17,CUL3,RHEB,RNF40,RBBP8,YWHAZ,BRCA1,CXXC5,GNA11,CDKN2C,TOP2B,PCNA,SRSF8,PELI1,TRIM37,MAGEC2,FEN1,B3GNT2,ERRFI1,PPP2R1A,LPAR6,SMARCB1,RNF126,CYB5B,SIN3A,NKX3-1,BAZ1B,MAP1S,P2RY10,ACTL6B,IKBKB,TRAF6,KDM2A,CBL,UCK1,DDX1 |
| 3.437e-05 | -10.28 | MRPL45 (mitochondrial ribosomal protein L45) | protein interactions | 84311 | 198 | 82 | 19454 | 5460 |
TUFM,RPL26,PMPCA,CUL3,AUH,MTG2,TRIM23,MRPL13,CCDC90B,MTG1,FAU,MRPL53,TACO1,RPL19,PRRC2A,VIRMA,RPL35,RPL13A,MRPL23,MRPL12,RBMS2,MRPL10,RPL27A,MTRES1,MRPS18A,FOXS1,RPA2,GFM1,EXD2,NGRN,RPA3,UTP23,FBXW7,MRPL41,TMEM177,MRPL17,HSCB,HNRNPA1,MRPL9,PFDN5,RPL6,MTRF1,SYNJ2BP,GRSF1,MRPS26,CHCHD1,SNRNP70,TMEM70,RHOG,MRPL18,GATD3,FAHD1,PRR3,ALYREF,SDHB,SSBP1,MRPL24,MALSU1,MRPL50,METTL15,APOBEC3D,AURKAIP1,MRPL11,MRPL47,MARCKSL1,MRPL51,MRPL49,GFM2,MRPL33,PDHA1,COX8A,HINT2,MRPL52,HSPD1,RIGI,IMMP2L,RPL17,FASTKD5,SRSF4,MEPCE,NUP42,G3BP1 |
| 3.437e-05 | -10.28 | VAC14 (VAC14 component of PIKFYVE complex) | protein interactions | 55697 | 198 | 82 | 19454 | 5460 |
MPPED2,BCL2L1,AMT,LAMP2,ATG9A,SIGLEC5,TMBIM6,DDRGK1,FIG4,XPO1,EIF2S1,SMUG1,SLMAP,EGLN3,SPMIP9,EEF1AKMT3,CD274,HDHD3,NGB,PCMTD2,CD209,NUDT19,TFRC,VAC14,MTCH2,COMTD1,TOP3B,METTL15,KHDC1,CRYBA2,TRIM63,LASP1,CD80,LSM4,PELI1,CYTH2,HS2ST1,PHF1,PHYKPL,BHLHE40,ATP2B4,RNASEH2C,CRYBA1,ZMPSTE24,CUL3,PBLD,GPR17,HNF1B,MGAT5B,PHKA1,NTAQ1,EIF4A2,MGST3,OTOS,SRPK2,DDAH2,GNAI2,ESR2,APEX1,GNB1,VAMP3,UFSP1,LMBR1L,CNTN2,WRAP53,EHHADH,PRR13,WDR83,FAM234A,RBFOX2,HCST,NDUFAB1,HSCB,NPTN,GINS3,FAM50B,RPA3,ACTMAP,BAP1,EP300,MAVS,RAB9A |
| 3.439e-05 | -10.28 | ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1) | protein interactions | 55139 | 43 | 25 | 19454 | 5460 |
PSMD12,PSMA5,FBXW7,STAT6,PSMC3,PSMB7,NAA35,PSMC4,RAF1,EGLN3,ESR2,NRSN2,PSMD6,PSMC5,CTTN,PSMA6,CA2,FAS,PSMD7,RC3H2,XPO1,SNRPB,PSMD3,PSMB2,EDEM1 |
| 3.439e-05 | -10.28 | ATG2A (autophagy related 2A) | protein interactions | 23130 | 43 | 25 | 19454 | 5460 |
RAB4A,GABARAPL1,MAP1LC3B,OTULINL,TOP3B,RIGI,PHB2,RAB3B,RAB9A,DNAJC7,ATG3,DCAF4,ATG7,XPO1,H2BC9,EDEM1,RAB5C,UBTD1,VIRMA,ARF6,MAGED2,WDR45,MAP1LC3A,OPTN,S100A6 |
| 3.442e-05 | -10.28 | UBA3 (ubiquitin like modifier activating enzyme 3) | protein interactions | 9039 | 86 | 42 | 19454 | 5460 |
UBE2F,RNF7,LMNA,CAPN2,UBE2M,RAF1,NAA15,SYNRG,ANAPC13,JUN,PPP2R1A,NSFL1C,TRIM63,NEDD8,NF2,KDM1A,KRAS,COPS4,IMPA2,SAR1B,TXNDC17,RPA3,NAE1,CPNE2,SKIC8,UBE2H,RIT1,MCM3,XPO1,ATG7,COPS5,PRNP,KCTD10,PRDX2,UBA3,PELO,DFFA,OPTN,COPS2,LDLR,NT5DC1,DSTN |
| 3.442e-05 | -10.28 | TRABD (TraB domain containing) | protein interactions | 80305 | 86 | 42 | 19454 | 5460 |
EGLN3,UQCRQ,SLC25A12,ADCK1,NT5DC1,LMBR1L,COQ8A,CCNF,PHB1,UHMK1,FIS1,HAX1,ILK,LAMTOR1,NME2,BECN1,RHOB,PPTC7,TOMM40,RNF40,SLC25A46,MARCHF5,CUL3,FBXL4,HSCB,CDK20,SLC25A51,HSPA8,MAVS,AKAP1,HSDL1,MAP1B,RPA3,EXD2,BCKDK,RND3,RPA2,SAMM50,CDC42,COQ8B,MTCH2,MTX2 |
| 3.442e-05 | -10.28 | UBE2V2 (ubiquitin conjugating enzyme E2 V2) | protein interactions | 7336 | 86 | 42 | 19454 | 5460 |
RC3H2,MUL1,BCL10,VPS26A,TRIM32,SIAH2,SHPRH,SIAH1,ACTB,TRIM54,TTC9C,UBE2L3,LRIF1,UBE2N,TUBA1B,STUB1,SEC23A,MOB4,UBE2B,ZNRF1,RNF8,RAD23B,ZRANB2,UBE2M,TP53,TPT1,UBE2V1,TRAF2,CD2BP2,ETFA,TRIM63,RBCK1,CHCHD2,UFM1,IGSF21,CPLX1,RNF11,ARGLU1,ZYX,TRIM5,BIRC2,HAPSTR1 |
| 3.456e-05 | -10.27 | HIPK2 (homeodomain interacting protein kinase 2) | protein interactions | 28996 | 94 | 45 | 19454 | 5460 |
XAF1,HMGA1,DYRK1B,SIAH2,TP53INP1,NKX3-1,SMAD3,MYBL2,SUMO2,SUMO3,HNRNPL,MDM2,TP53,SMAD1,DDX39A,TRAF2,CBX3,ZYX,FBXO3,FHL3,PAX6,CREBBP,AR,RUNX1,CXCL1,DCAF4,MECP2,SPOP,RGMA,SMAD2,STUB1,UBE2I,ZMYM2,SIAH1,VIRMA,DYRK1A,SUMO1,WSB1,CTBP1,HEXIM1,PML,DDX39B,EP300,FBXW7,AATF |
| 3.459e-05 | -10.27 | proteasome core complex, beta-subunit complex | cellular component | GO:0019774 | 11 | 10 | 19108 | 5553 |
PSMB1,PSMB9,PSMB7,PSMB10,PSMB6,PSMB4,PSMB11,PSMB3,PSMB5,PSMB2 |
| 3.459e-05 | -10.27 | PAWR (pro-apoptotic WT1 regulator) | protein interactions | 5074 | 124 | 56 | 19454 | 5460 |
EED,SNX2,CAND1,HMG20A,HDAC6,PPP3CA,ABCF1,PSME1,FAF1,TFPT,SPSB1,TRIM21,TOM1,G3BP1,TNF,KRAS,FBXO25,RAF1,THAP1,MAP1LC3B,DDX39A,CAPZA2,APEH,CCNF,RRAS2,ACTB,TXN,STAT1,DAPK3,SSH3,APEX1,DYRK1A,VIRMA,IDE,HNRNPC,NIBAN2,MYC,CARS1,BTF3,BICD2,HTR1A,PML,BAP1,DDX39B,PPM1G,MIA2,SQSTM1,TXNL1,NUCKS1,HSPA5,AATF,SHMT1,ATP6V1C1,CFTR,DET1,CNDP2 |
| 3.471e-05 | -10.27 | H1-10 (H1.10 linker histone) | protein interactions | 8971 | 257 | 102 | 19454 | 5460 |
RPL23A,METTL18,FAF1,RIGI,H3C1,VRK1,SRP72,APEH,DNAJC2,NECAP1,AIFM1,KRR1,MBD5,ZBTB2,FZR1,SPPL3,CAND1,RPS16,TOP1,HDAC6,H2AC14,ENY2,GRSF1,H2AC4,SNRNP70,EXOSC4,RNF113A,BAP1,HELLS,SOD1,RPA3,SIRT7,AATF,NUCKS1,RPL4,FBXW7,CDC42,CDK7,XBP1,CFTR,TPT1,HEXIM1,RPA2,PSPC1,CCNF,CTTN,METAP2,ZNF330,DYRK1A,NMI,DNAJC8,RPL7A,CALU,UBE2H,RC3H2,RPS24,RPL31,PABPC1,TNF,G3BP1,VDAC1,OTUD6B,SOX2,H1-3,MSX2,B3GNT2,EZH2,PDHA1,HDAC11,EED,DNM2,PHB1,RPS10,HNRNPA1,DDRGK1,MAP3K14,HMGA1,IFI16,VPS26A,WWP2,HNRNPD,DRG1,AGR2,KDM2A,NCK1,G3BP2,UFL1,H1-5,PAFAH1B1,SEC61B,DLST,POLR2B,NCKAP1,ESR2,RPL10,RPL19,TRIM29,RPL35,MYC,GRB10,TM9SF4,CUL3 |
| 3.483e-05 | -10.26 | ATP6V1E1 (ATPase H+ transporting V1 subunit E1) | protein interactions | 529 | 113 | 52 | 19454 | 5460 |
ATP6V1A,THY1,TLDC2,TYMS,COX4I1,ALYREF,SSBP1,NDUFS8,UQCRH,ATP1B1,ROGDI,TMOD2,ATP6V1D,DRG1,CBL,TRAF6,POR,SFXN1,SOCS2,XPNPEP1,S100A10,TRIM26,KRAS,EMC8,PPIF,SOX2,SLC25A24,NUPR1,CYB5B,NDUFS3,NHERF1,TFRC,ATP6AP2,LAMTOR3,YES1,HMOX2,SLC30A5,HMGCS1,SAMHD1,SUGP1,RIT1,ATP1B3,HSPB2,RHOU,ABCC2,ATP6V1G1,ATP6V1G2,UQCRC1,ATP6V1C1,ATP6V0E1,PICALM,PTP4A2 |
| 3.483e-05 | -10.26 | ARHGAP36 (Rho GTPase activating protein 36) | protein interactions | 158763 | 113 | 52 | 19454 | 5460 |
USP15,MRPS26,HAX1,STOML2,CLPX,DDX50,PDIA3,NT5C2,API5,XPO1,CSNK2A1,PPIB,CAND1,NOP58,HACD3,COQ8A,RPN1,SLC25A24,LBR,SRPRB,HSPE1,FARSA,CSE1L,KPNA2,HUWE1,CHCHD2,RPS27A,MAGED4B,PREPL,ZYX,HSD17B10,SDF2L1,RPS29,PRKACB,TAB1,CHCHD3,PSPC1,ARF1,ACAT1,MRPS28,GANAB,STOM,USP39,ATP5PO,NDUFA5,SUFU,RBFOX2,TOMM22,MRPS7,CLU,TMEM263,PPM1G |
| 3.483e-05 | -10.26 | CARS1 (cysteinyl-tRNA synthetase 1) | protein interactions | 833 | 113 | 52 | 19454 | 5460 |
HNRNPA1,ATG7,GTF2E1,GSTM3,KARS1,WWP2,TRAF6,SEC23A,AIFM1,KMT5B,SPPL3,CAND1,SUMO2,GFPT1,MLLT6,EEF1A1,TXNRD1,APEH,FAF1,PSMD12,KRAS,CTNNBL1,TRIM63,PSMD1,BTF3,CARS1,RIT1,BRCA1,CTNNA1,EIF2AK2,IDE,GNB1,PPAT,PRDX3,ATG16L1,SHMT1,RARS1,PIH1D1,PTP4A2,RPA2,PICALM,HSPA8,DDX5,TTC1,SNAPC1,DVL2,PPM1G,RPA3,PACSIN3,LITAF,STAU1,EEF1G |
| 3.491e-05 | -10.26 | CACYBP (calcyclin binding protein) | protein interactions | 27101 | 263 | 104 | 19454 | 5460 |
ILK,HSP90AA1,LAMTOR1,BEX3,FAS,SNRPB,PRPF31,HNRNPAB,PSMA4,ACO2,USP13,MYC,TUBB,SIAH1,PRDX2,TAGLN2,ANAPC2,S100A6,CSNK1A1,PIH1D1,DET1,RND2,RNF41,SKP1,PXMP2,STAU1,EYA3,UFL1,HNRNPA0,AKAP1,HSPA8,PEBP1,HNRNPD,PPM1B,FKBP4,AGR2,RHOG,CTNNB1,SIAH2,DDRGK1,PRDX1,IFI16,MAPK4,HSP90AB1,STK3,DIRAS3,EGLN3,CACYBP,ADCK1,OTULIN,RHOBTB1,CHMP4C,GLE1,EEF2,ISG15,TPD52,TESK2,RUVBL2,RPAP3,EWSR1,S100B,UBE2H,PEA15,FBXO7,RPL7A,PTPN11,VIRMA,UBB,CCR2,NDN,UBE2I,OPTN,CCNF,TSSK1B,STUB1,PRKCA,HSP90B1,SAMM50,RPA2,POLR1D,ATG16L1,SQSTM1,DERL1,RPA3,BAP1,DNAJC7,TUBG1,GAPDH,SLC25A12,LMAN1,FZR1,PREP,HRAS,ACTR2,CBX3,EEF1A1,ACTR1A,FKBP8,PTGES3,HSD17B10,PSME1,FAF1,RAB1A,DDR1 |
| 3.501e-05 | -10.26 | SETDB1 (SET domain bifurcated histone lysine methyltransferase 1) | protein interactions | 9869 | 201 | 83 | 19454 | 5460 |
CDKN1A,SUFU,PPP1R8,HECTD1,ANXA7,ADNP,CCDC106,ZFP64,HADHA,RNF10,TTC1,SAT1,PML,OLFML3,FBXO30,BRIX1,POLA2,ZDHHC17,UBE2K,TTR,KDM1A,HMOX2,EXOC5,CUL3,GPR17,LDHB,AKT1,CREBBP,UBE2H,HSP90AA1,UBE2I,PRKRA,MOB4,ZMYM2,EFHD2,PAFAH1B3,ZBTB33,BTG3,ERH,LRIF1,CBX5,THAP8,FAF2,PHF13,CDK4,CFAP68,ZNF263,SERPINB9,CRELD1,MAD2L1BP,DAP,CBX3,CLPB,BHLHE40,PSME1,TCOF1,ORAI2,SNIP1,MAP1B,AKT2,SMN1,TOLLIP,GNL1,S100A10,H3C1,SUV39H1,MZT2B,XPO1,SNAP91,ZNF24,MOV10,POU5F1,TIAM1,GSTO1,ARL14EP,RB1,RPLP2,SIN3A,AIFM1,FAM118B,MDM2,SUMO2,SLC38A3 |
| 3.501e-05 | -10.26 | RACGAP1 (Rac GTPase activating protein 1) | protein interactions | 29127 | 201 | 83 | 19454 | 5460 |
STX18,BCL7B,ZYX,AKT2,H3C1,G3BP1,KRAS,CHN2,VRK1,ROCK2,RAF1,TOP3B,E2F4,DLG3,NUPR1,SMNDC1,CHMP4C,CAPZA2,SYNCRIP,TRAF3IP3,EGLN3,SURF6,CDC5L,FZR1,FAM98A,ARF6,PLG,YWHAH,YWHAG,MPG,DDRGK1,IFI16,HMGA1,PIK3R1,YWHAB,MED21,TUBG1,H2AC4,PSMD7,SQSTM1,RPA3,CSTB,GID8,TMEM263,GPC1,STAU1,PPP1CB,RND2,CD2AP,KLF12,TANK,SLC16A10,PRSS23,LMNA,CDK1,RPA2,IPP,RTRAF,SYBU,TRIM27,CCNF,ZNF330,PSMA6,LIG3,RSRC1,DYRK1A,APEX1,RPGRIP1L,TAB1,SAMHD1,PSMD1,RACGAP1,MYC,SFN,MORF4L1,PKP4,ANAPC4,RIT1,VMP1,ELMO2,BRCA1,RHOB,YWHAZ |
| 3.505e-05 | -10.26 | PNN (pinin, desmosome associated protein) | protein interactions | 5411 | 269 | 106 | 19454 | 5460 |
MAD2L1,ESR2,SNRPB2,ERH,SNRNP40,SNRPD2,PELO,DLST,CDKL2,FYTTD1,RHOB,BTF3,SNRPB,MYC,CFAP20,HNRNPC,SAP18,HSPA8,SF3B1,DDX39B,SNRPA,NKAPD1,CTBP1,PCLAF,LARP4B,RALYL,PABPC5,ZC3H14,SRSF10,PAIP1,C1QTNF1,SNRPA1,DYNC1I2,BRD9,KRT8,RSBN1L,MAGOH,DDX23,YWHAH,YWHAG,HNRNPA1,TRA2A,IFI16,PRPF19,RPL6,SRSF4,SSRP1,KRAS,SRSF7,ARGLU1,NFKBIL1,SKA3,HDAC11,CHMP4C,PDHA1,ANAPC13,B3GNT2,SUPT5H,SRPK2,GSK3A,RBMX2,EIF4A3,ELAVL2,CASC3,UBE2H,PPIG,PPP1CC,AR,HMGB1,RBM22,CLK1,RNF113A,RPA3,SIRT7,NOG,WWP1,ZCCHC17,DENND2D,SF3A1,AKAP17A,CDK9,RBM42,CDC5L,ZBTB2,TOP1,NKAP,ITK,BRD3,NOS1AP,SNRNP70,CSNK2A1,API5,ZMYND11,RIGI,CAMKV,CDC40,THRAP3,ZC3H11A,SNIP1,TCEA2,ILF2,TOPORS,NUPR1,PSMC3,CD2BP2,TBK1 |
| 3.509e-05 | -10.26 | TUBB2A (tubulin beta 2A class IIa) | protein interactions | 7280 | 281 | 110 | 19454 | 5460 |
HUWE1,FBXO25,MEPCE,FAF1,TFCP2,DISC1,CAPN2,SERPINB9,KBTBD4,TP53,MAP2K3,ZMYM4,VCPKMT,FZR1,MDM2,RCHY1,EEF1AKMT3,TES,SSX2IP,CLP1,MICB,LAMP3,HDAC6,PPM1D,CD81,IRF7,FBXW7,METTL22,RHOU,BAP1,SQSTM1,RPA2,TCP11L1,HEXIM1,ARL15,TMOD1,TPT1,HCST,CFTR,CNP,KCTD9,RHOJ,CDC20,PAFAH1B3,TUBA1B,PTEN,TRIM23,UBE2H,RSPH1,RAB2A,MORF4L1,ETFBKMT,RUNX1,FBXO7,TUFM,USP14,VDAC1,RUVBL1,FLOT1,EZH2,TUBB4B,PDHA1,MOB3C,HGS,B3GNT2,SOX2,TUBA1A,ELK1,EGLN3,CCT7,SSR2,TNIK,PHB1,FBXO32,RPLP1,KRT8,AGR2,CBL,AHSA1,RPL23,FAM174A,DDRGK1,NSFL1C,ADRB2,FBXL4,COIL,RABAC1,HSPA8,SAT1,PSMA3,PLAA,PPT1,WDR77,ALKBH3,KCND3,STXBP1,TUBB,ESR2,PAPSS2,LMBR1L,AP2M1,CCT2,LAMTOR1,FAS,PSMD14,KLK5,ILK,CUL3,CUL2,BTF3 |
| 3.515e-05 | -10.26 | NFS1 (NFS1 cysteine desulfurase) | protein interactions | 9054 | 138 | 61 | 19454 | 5460 |
PICK1,HINT2,GPSM3,COX8A,HSPD1,NDUFA4,FASTKD5,CDNF,ABHD10,IMMP2L,KRAS,LSM4,PPP2R1A,CARTPT,METTL15,MRPL11,GFM2,PHC1,GPX7,PDHA1,GATD3,AIFM1,SSBP1,COX4I1,RMND1,WIF1,ATG7,KLHL22,MTRF1,GRSF1,MRPS26,RHOG,SMAD4,CHCHD1,TMEM70,HDAC5,HSPA8,GFM1,PCGF2,EP300,RNF113A,NGRN,SOD1,EXD2,CRYZ,HSCB,ISCU,NDUFAB1,MTRES1,TACO1,CCDC90B,MTG1,USP5,PARL,TUFM,AUH,MTG2,PMPCA,RIT1,DNAJB6,ATG3 |
| 3.542e-05 | -10.25 | DDX23 (DEAD-box helicase 23) | protein interactions | 9416 | 462 | 169 | 19454 | 5460 |
MATR3,SNRNP40,FBXO22,TUBB,ERH,APEX1,SNRPB2,RSRC1,CMTR1,DLST,SNRPD1,MIRLET7B,SNRPD2,GTF2F2,GTF2F1,LMNB1,BRCA1,FTSJ3,MIR363,RIT1,MYC,PRMT6,PRPF31,SNRPB,MCM4,UFL1,STAU1,NOP53,EEF1G,COIL,SAP18,SNRPA,SLU7,NKAPD1,SF3B1,RNF10,DDX5,EP300,STK26,USP39,MFAP1,NOP58,LYAR,SNRPD3,LSM5,SRSF10,LRWD1,THOC2,MIR7-2,RBM5,MIR214,MIR141,RSBN1L,DDX50,IFI16,MIR143,HNRNPA1,DDRGK1,KRAS,DHX16,SRSF4,SSRP1,POLDIP3,MORC2,TOP2B,EWSR1,SLC35G2,SRSF7,CAAP1,CHMP4C,ZRANB2,SNRPE,OTULIN,RAF1,SUPT5H,DHX38,ISG15,RPS7,GTF2E2,SRPK2,VIRMA,CCNF,LIG3,GCFC2,RBMX2,LSM6,STK24,PIP4K2C,CDC73,PPIG,UBE2H,SUGP1,SUB1,PRKACB,AR,SMC4,FBXW7,HMGB1,BRIX1,HSPA5,AATF,HELLS,DDX46,RPA3,PRPF4,SIRT7,CLK1,MIRLET7I,KIN,RNF113A,LMNA,RPA2,LSM2,TFIP11,LUC7L3,MIR7-1,TXNL4A,SF3A1,WDR83,SNRPN,GABRA1,RPS16,NKAP,MIRLET7G,TOP1,RBM42,MIR429,AKAP17A,DKC1,SURF6,CDC5L,CWC15,H2AZ1,MIR106B,ALYREF,MIR25,TUBG1,MPHOSPH10,H2AC4,SNRNP70,CDK12,RBM17,PPIL4,GTF2E1,LSM4,PSMA5,TSSC4,THRAP3,KPNA2,MEPCE,SNRPG,MSH6,TCOF1,NKRF,HAPSTR1,RP9,DDX42,DISC1,RBM34,IK,NUPR1,CERK,TBK1,SRFBP1,WBP11,CD2BP2,H2AX,MIR200C,EEF1A1 |
| 3.555e-05 | -10.24 | GPC1 (glypican 1) | protein interactions | 2817 | 175 | 74 | 19454 | 5460 |
CLU,EEF1G,NSFL1C,HNRNPA0,UCHL3,SRSF2,SPCS2,SQSTM1,HADHA,PGK1,WNT2,FKBP1A,EIF4B,LRRTM3,LMNA,WDR77,SF3A1,RPL27A,ERH,TAX1BP1,SPCS1,RPS20,PTEN,OAF,FGFBP1,CTTN,S100A6,VEGFA,SORD,MDH1,MAPRE1,RPS5,CGRRF1,S100A11,SPCS3,RACGAP1,HBEGF,SFN,RPL7A,MYC,HNRNPK,CAMKV,G3BP1,SEC11A,HINT1,RPL23A,ATP2B4,NUPR1,NHERF1,EZH2,H1-3,RPSA,CMPK1,RMND1,PPIA,RPL12,SRP14,EEF1B2,FOLR1,SYNCRIP,HNRNPD,RPS2,FKBP4,CTNNB1,TPM3,DAG1,YWHAH,HDAC6,FGF1,PPIB,RPL6,PFDN5,USP3,HMGA1 |
| 3.618e-05 | -10.23 | HAX1 (HCLS1 associated protein X-1) | protein interactions | 10456 | 397 | 148 | 19454 | 5460 |
GEMIN7,NEFL,GPD2,TFCP2,APOO,CTDSP2,MTCH2,FAM13B,FKBP8,RIGI,DUSP21,FBXO25,L1CAM,DNAJC30,CAMKV,HUWE1,IGF1R,EMC2,ABCE1,HAPSTR1,CLPB,SFXN1,RAB3A,DNAJC4,DNAJC7,SHC1,BECN1,GNG2,SNAP91,SLC25A46,MOV10,PLGRKT,SLC25A12,LMAN1,PRNP,SPPL3,TES,RGS1,RNF128,COX4I1,KIAA0513,HCLS1,AIFM1,PTPN22,STX17,CFTR,GABRA1,POLR1D,SEC22B,POLR1H,CLU,HSPA5,SLC25A51,YKT6,NAPG,RNF113A,MAVS,GRIA2,TMEM263,UBE2H,DNAJC19,RC3H2,GEMIN8,SYP,AR,HPCA,RAB2A,MLF1,VIRMA,CDC20,UBB,PPAT,RAB14,GNAO1,CTTN,CCNF,STUB1,GNAQ,RAB6B,GDI2,AQP3,PDHA1,NUDT19,HPCAL1,HOXB1,ERLIN2,DNAJC25,TUBA1A,MAPK10,RAF1,FLOT1,MATN4,CDK20,LASP1,PSMA1,USP30,GPM6B,EWSR1,ARGLU1,HSPB1,STX1A,CDH13,SLC25A28,RHOG,EIF3D,XPO1,NDC80,PIK3R1,HSP90AB1,NUF2,COX14,EGLN3,MAGED2,PHB1,WDR6,CBFB,ABCB1,DUSP22,RAB6A,TIMM29,STXBP1,TANK,H1-5,NCALD,DUSP26,GPM6A,PHB2,UFL1,IL1A,CNTN1,AKAP1,RAB5A,ILK,HTRA2,HSP90AA1,NTRK3,CRMP1,CKB,ARHGAP19,RFC5,CUL3,CDKN3,ESR2,PARL,POLR2B,ATP5F1B,MTM1,PELO |
| 3.630e-05 | -10.22 | apoptotic signaling pathway | biological process | GO:0097190 | 315 | 126 | 18204 | 5365 |
ATF4,TFPT,DDIT3,FASLG,DAPK3,RNF41,STK3,IFI6,TNFSF12,ITGAV,RB1CC1,SST,PRDX2,PCGF2,IL12A,ADORA1,BAX,FLCN,SFRP1,IER3,GGCT,DDX5,DAPK1,FHIT,SOD2,NUPR1,TMEM117,BLOC1S2,DYRK2,STK4,TLR3,MAEL,IFNG,TP53,IFI16,SFN,BEX3,RPS27L,ARL6IP5,NBN,PSEN1,HTRA2,PIK3R1,TNFRSF1B,STK24,CUL3,MCL1,BRCA1,PMAIP1,CD28,BNIP3L,IL7,CUL2,CAV1,IFI27,HINT1,TICAM1,CDIP1,BCL2A1,IVNS1ABP,GABARAP,DDIT4,PYCARD,HRAS,STK11,SMAD4,CLU,DNAJC10,EPHA2,DELE1,ACVR1B,AIFM1,IL1B,TMBIM6,FGF10,CTNNB1,TRAF2,BAK1,PDIA3,GPX1,SELENOK,EDA2R,CRIP1,EP300,POLB,TNF,PDCD10,VDAC2,RAF1,SMAD3,TGFB2,IL1A,CX3CL1,PARP2,BOK,TOPORS,IL2,FIS1,MSH6,RRN3,SIVA1,PRKCA,CD38,GSKIP,ERO1A,MLLT11,BAG3,CTNNA1,FAS,CYP1B1,CASP4,GSK3A,CRADD,BAD,DAP,KRT8,G0S2,DEDD,CTTN,BCL2L1,JAK2,PML,CIDEB,ZNF622,ING5,CDKN1A |
| 3.640e-05 | -10.22 | positive regulation of phosphorylation | biological process | GO:0042327 | 619 | 228 | 18204 | 5365 |
DUSP19,PPIA,MMP9,CD86,IFNA10,IL6,MOB3B,IGF1R,TOM1L1,ERP29,FERMT2,IL12B,TLR3,EPHA4,UBE2K,CCL5,VEGFC,FLOT1,CLIP3,MAP3K12,HSP90AA1,HAX1,CSF2,IL6ST,PRNP,TPD52L1,BCL10,HTR2A,IL12A,MIF,PSRC1,EFNA5,PRKAG1,HSP90AB1,AGAP2,CD80,CD36,UCN,DSTYK,CLEC6A,MAVS,TAB1,CAV1,IFNB1,SMYD3,MAD2L2,PSEN1,IFNA2,CD4,MIR21,MIR30B,HBEGF,TNIK,EHD4,LCP2,IL4,NPTN,RGCC,CREBL2,EMP2,HDAC3,IFNK,MOB3C,CCND3,MT3,TF,TXN,GH1,FGF10,OSBP,TGFB2,PIK3R3,MAP2K3,PDCD10,KRAS,IGF1,GREM1,ADRB2,ADTRP,PROX1,TNFSF18,CCR7,TLR6,SLCO3A1,IFNA13,IL1B,BTBD10,AKT1,TNFSF15,RAP2B,BAD,FCGR1A,MAP2K1,GSK3A,DVL2,NRP1,FGF1,JAK2,MMD,IL5,DLG3,CRKL,CARTPT,DIRAS2,AR,PAK2,MIR221,IL2,TGFBR2,CCND1,KIT,SOX9,FAS,ODAM,LMO4,MET,IL13,LEPR,CAMP,IL21,CACUL1,KCTD20,ITGA6,TCIM,TP53,TAB2,IFNG,NTF4,STK4,DIPK2A,SDCBP,CCNY,TLR4,APLNR,SQSTM1,LEP,DLG4,PIK3CG,PTPN11,PHB2,RAP2C,ANGPT1,PTPN1,FGF22,SRC,GHR,IL18,RB1CC1,CSH1,MIR26B,PTGES3,P2RY1,FGFR1,CHRNA7,EZH2,IL3,SEMA7A,VEGFA,IL23A,IL34,FGF23,EPO,IL15,CAMK1,NBN,NTRK2,NTRK3,FAXDC2,OSM,GPNMB,CDKN1B,RAP2A,YES1,TFRC,PHB1,RPS3,TRIM6,LACRT,TRAF2,RAP1A,CX3CR1,WEE2,ROCK2,CX3CL1,RAF1,ADIPOQ,TNF,FGF17,FGF3,MAP3K11,DDRGK1,AGER,STK11,HRAS,PRR5L,CAB39,HDAC6,NKX3-1,FBXW7,CD40,RALB,EPHA2,SYK,FGF16,FGF7,ADNP,STRADB,PIH1D1,TESK1,ILK,CDKN1A,ZNF622,ARL2BP,HCLS1,CHI3L1,MAP2K6,PSMD10,TNFRSF14,TBK1,XRCC5,CCL19,F2,DIRAS1,CLDN3,ACVR1,RARRES2,TRAF6,DDR1 |
| 3.655e-05 | -10.22 | E7 (transforming protein E7) | protein interactions | 1489079 | 178 | 75 | 19454 | 5460 |
NDFIP1,ACTB,HECW1,TRIM54,JUNB,UBB,SCNM1,ENO1,ACKR3,AP2M1,FBXW11,TFDP2,PPIG,AP2A1,CUL2,CUL3,HNRNPAB,CREBBP,MYC,TRIM32,LMO2,CDC16,IRF1,TRAF3IP2,EEF1G,CCND3,RNF11,TRIM3,PML,BTBD10,SNAPC1,H2BC12,TNFAIP1,TRIM22,SPCS2,SYVN1,TRUB1,TOX4,ZER1,ZBTB42,SAP30BP,CCNA2,CDKN1A,CNP,AKIP1,IGFBP3,TRIM15,MIF,FZR1,FUBP3,RPL9,PSMB1,RB1,TRAF6,MAP1S,TOR4A,ELOC,ZBTB14,ZBTB16,SOCS2,UBE2A,ZBTB25,KLHL25,STX8,CDK5,PCNA,TRIM21,JAK1,RPL3,PDLIM4,CDK4,E2F4,EEF1A1,TRAF2,JUN |
| 3.660e-05 | -10.22 | Proteasome_suB-type | interpro domains | IPR023333 | 11 | 10 | 18521 | 5414 |
PSMB4,PSMB2,PSMB5,PSMB3,PSMB11,PSMB1,PSMB7,PSMB10,PSMB9,PSMB6 |
| 3.683e-05 | -10.21 | WDR11 (WD repeat domain 11) | protein interactions | 55717 | 127 | 57 | 19454 | 5460 |
HAPSTR1,RING1,LRRN4CL,PSMA1,PSMA2,PTGES3,SSRP1,DHX38,MGARP,GABARAPL1,ZNF397,CBX3,DISC1,AQP3,RAB4A,PHB1,ARL10,RAC2,HNRNPL,FZR1,ARF6,RHOH,TNFAIP6,ATG9A,LAMP2,RAB5C,DDRGK1,RHOG,SNRNP70,DRG1,CXCR4,RPA3,HSPA8,RAB9A,EP300,TRIM52,HSPA5,BET1,KDELR2,CDC42,RND2,RPA2,PSMA6,COPE,ESR2,VIRMA,EMILIN1,MYC,SMARCA5,RAB11A,PSMA4,CUL3,FAS,LAMTOR1,FBXW11,XPOT,UBE2H |
| 3.695e-05 | -10.21 | LLGL1 (LLGL scribble cell polarity complex component 1) | protein interactions | 3996 | 141 | 62 | 19454 | 5460 |
RND2,CDC42,TIMM13,RPA2,CD46,RNF146,PARD6A,RPA3,RHOU,NUBP2,RAB5A,SQSTM1,RAB9A,HSCB,STX7,RAB2A,MYC,CUL3,RAB11A,DNAJC5,LAMTOR1,RHOB,FBXW11,NTRK3,HSP90AA1,UBE2H,TRIB1,CCNF,PPM1M,COPE,RHOJ,ESR2,GABARAPL1,TUBA1A,RND3,POLR2C,NTRK2,BAG2,IGF1R,KRAS,FLOT1,PTGES3,LAMP2,UBXN6,RAB5C,LAMP3,RHOG,DNAJC7,ARL11,HRAS,RAB35,EEF1AKMT3,GJA1,RAC2,ARF6,TOP1,RHOH,LMAN1,DIRAS3,STX6,EGLN3,CAV1 |
| 3.695e-05 | -10.21 | UBE2K (ubiquitin conjugating enzyme E2 K) | protein interactions | 3093 | 141 | 62 | 19454 | 5460 |
BRCA1,RC3H2,MARCHF3,SLC7A11,CCNB1,BAG3,BFAR,SIAH1,TSN,TXN,DEK,SMURF1,UBB,CCNF,UBE2I,TRAF7,TRIM27,SDCBP,ARL15,TPT1,UBA52,UBLCP1,RNF182,RNF5,NF2,RNF41,DDI1,ZDHHC17,TXNDC17,TRIM3,HELLS,RLIM,TRIM5,HSPA8,CASP12,SKIC8,WWP2,NFKB1,TRIM34,HNRNPA1,PRNP,HNRNPL,FZR1,TRIM35,MDM2,UBE2N,TYMS,KRIT1,TP53,DSTYK,UBE2V1,TRIM63,RBCK1,ANAPC11,H3C1,NEDD8,RIGI,PAX6,RNF167,RAB1A,PICK1,RING1 |
| 3.707e-05 | -10.20 | CAT (catalase) | protein interactions | 847 | 158 | 68 | 19454 | 5460 |
FAM20C,ACOT8,MOV10,PRDX1,TLR10,CD274,GNPAT,FAHD1,DECR2,PHYH,G6PD,PNPLA8,TP53,B3GNT2,HSDL2,PGM1,SOX2,MAP1LC3B,DISC1,STIM1,NUDT19,MOB3C,CSTPP1,RNF8,TBC1D19,SOD2,MYO1B,HSPE1,PSMD12,PTPN11,LDHB,GSTK1,MYC,MLF2,CFL1,CFL2,YWHAZ,MECP2,SNX5,UBE2H,SORD,CTNNA1,ENO1,ZBTB33,GNG12,ACOX1,CCNF,UBE2I,PTEN,CTSB,PRDX2,LDHA,DYRK1A,SCML2,EHHADH,CFTR,NEK2,DHRS4,METTL14,ISOC1,NUDT12,JUP,RPA2,SOD1,DDX39B,RPA3,ATP5IF1,GRPEL1 |
| 3.707e-05 | -10.20 | SMPD4 (sphingomyelin phosphodiesterase 4) | protein interactions | 55627 | 158 | 68 | 19454 | 5460 |
TMPO,STX6,LMAN1,NUP35,ARF6,DNAJC1,RHOH,EED,HSD17B11,GJA1,RAC2,RAB35,PTPN1,DNAJC7,PEX3,HAX1,STYK1,ESYT1,LAMP3,ATG9A,SLC25A46,FAM20C,MARCHF5,RAB5C,FKBP8,NUP107,KRAS,RAB3B,CYP2C9,TMT1A,FURIN,RPN1,STIM1,AQP3,RAB4A,NUP153,DNAJC25,CCDC47,SRFBP1,SEC63,ESR2,RMDN3,ANAPC2,SEC61B,CCNF,MAPRE1,LMNB1,NONO,CIAO1,FOXA3,RAB11A,CUL2,STX7,PXMP2,EXOSC4,HSPA8,RAB9A,DERL1,RAB5A,RPA3,LMNA,SSR1,SEC62,CDC42,RND2,OTULINL,ST7,ATG16L1 |
| 3.718e-05 | -10.20 | Toll Like Receptor 7/8 (TLR7/8) Cascade | REACTOME pathways | R-HSA-168181 | 93 | 48 | 10285 | 3229 |
IKBKB,TICAM2,DUSP3,TRAF6,HMGB1,CD14,MYD88,RPS27A,TAB2,ATF1,NFKBIB,MAPKAPK3,TLR3,MAP2K6,MAPK10,UBE2N,TICAM1,PPP2CB,IRF7,UBE2V1,MEF2A,DHX9,SKP1,MAP2K3,TLR7,NFKBIA,MEF2C,MAP2K1,TLR4,UBA52,PELI1,PPP2R1A,PELI3,UBB,ELK1,CREB1,TAB1,FOS,S100B,DUSP6,IRAK4,NFKB1,LY96,TLR8,JUN,AGER,TLR9,FBXW11 |
| 3.718e-05 | -10.20 | MyD88 dependent cascade initiated on endosome | REACTOME pathways | R-HSA-975155 | 93 | 48 | 10285 | 3229 |
DUSP3,HMGB1,TRAF6,IKBKB,TICAM2,MYD88,CD14,RPS27A,TLR3,MAPKAPK3,MAP2K6,TAB2,ATF1,NFKBIB,UBE2N,MAPK10,IRF7,UBE2V1,TICAM1,PPP2CB,DHX9,MEF2A,SKP1,NFKBIA,MAP2K3,TLR7,MAP2K1,MEF2C,PELI1,PPP2R1A,PELI3,UBB,TLR4,UBA52,ELK1,CREB1,DUSP6,S100B,TAB1,FOS,LY96,TLR8,JUN,AGER,IRAK4,NFKB1,TLR9,FBXW11 |
| 3.788e-05 | -10.18 | FAM162A (family with sequence similarity 162 member A) | protein interactions | 26355 | 68 | 35 | 19454 | 5460 |
GHITM,RPA2,UBL4A,SSR3,SLC25A51,VDAC1,ADRB2,SLC7A14,EMC1,SIAE,MRPL22,NDUFA4,SFXN1,RPA3,RAB5A,GPM6B,TMEM70,LMNB1,ATP1A3,CBL,HSP90AA1,NRP1,TM9SF4,SLC25A1,SSH3,HNRNPL,COPE,VIRMA,PARL,SLC25A12,PRELID1,SPRED2,AIFM1,VDAC2,RMDN3 |
| 3.788e-05 | -10.18 | GTPBP6 (GTP binding protein 6 (putative)) | protein interactions | 8225 | 68 | 35 | 19454 | 5460 |
RIGI,MRPS17,ATP5F1D,TOLLIP,THBS3,GFM1,HINT2,AMACR,PSME1,EXD2,MTRES1,PDHA1,MRPL12,FAXC,MRPL11,TOP3B,ESR2,RAMP3,AGK,HNRNPL,MRPL23,GATD3,DKK3,YBEY,LURAP1,SSBP1,THTPA,RHOB,RPL24,TUFM,RUNX1,MTRF1,MTG2,EMILIN1,AUH |
| 3.804e-05 | -10.18 | TMEM126B (transmembrane protein 126B) | protein interactions | 55863 | 48 | 27 | 19454 | 5460 |
SFXN1,MRFAP1L1,NDUFB5,DHX9,NDUFC2,SLC22A6,FBXW7,SLC25A51,DNAJC30,IMMP2L,TIMMDC1,NDUFAF3,APOO,NDUFS3,AIFM1,LDLR,DHX15,ESR2,PARL,OPRL1,NDUFAF4,APEX1,APLNR,GPR17,AKT1,PDCD1,SPOP |
| 3.804e-05 | -10.18 | PTTG1IP (PTTG1 interacting protein) | protein interactions | 754 | 48 | 27 | 19454 | 5460 |
VAMP3,HRAS,AMIGO1,VTI1B,CAVIN2,STX6,ATP6AP2,RAB11A,RPS17,TMEM106C,PTTG1,NAPA,STX8,RPL27,NSDHL,CLEC7A,TTC1,KRAS,THRAP3,VAMP8,STX7,TP53,TMEM115,TFRC,RAB4A,EPHX1,STX12 |
| 3.804e-05 | -10.18 | MIGA1 (mitoguardin 1) | protein interactions | 374986 | 48 | 27 | 19454 | 5460 |
CHRM4,RAC2,DYNLL1,VIRMA,DYRK1A,APLNR,MARCHF5,GPR17,SLC25A46,NCR3LG1,FIS1,EXD2,AKAP1,MAVS,EFNB1,HSCB,FKBP8,TOMM20,MTCH2,MTX2,COMTD1,TOMM22,TMEM126A,HCST,CLEC2B,APOBEC3D,SIGLECL1 |
| 3.825e-05 | -10.17 | UBTF (upstream binding transcription factor) | protein interactions | 7343 | 219 | 89 | 19454 | 5460 |
RPL31,UBE3A,RPS24,COX8A,EWSR1,KRAS,GOLGA7,B3GNT2,SOX2,ACTN4,ISG15,CHMP4C,NFKBIL1,EZH2,LYAR,WIF1,WWP2,IFI16,DDRGK1,DDX23,AHSA1,NKAPD1,EP300,NOP53,STAU1,UFL1,COIL,ZMYM2,FBXO22,SNRNP40,RPL10,APEX1,RRN3,CREBBP,MYC,BTF3,BRCA1,ATG3,SERPINH1,DNAJB6,KCNA3,TCOF1,TOLLIP,H3C1,CAMKV,CDK4,TAF1D,CTDSP2,PIK3CA,CBX3,NUPR1,RCHY1,RB1,CGAS,SHPRH,VTI1B,CDC5L,ZBTB2,MDM2,TMPO,TLE1,CSNK2A1,BRD3,SIRT7,NOG,RPA3,RNF113A,FBXW7,UTP23,CCND1,SUMO1,ATG16L1,CFTR,CCNA2,GRM2,METTL14,RPA2,LMNA,ZNF330,FGFBP1,GSK3A,VIRMA,SRPK2,RPL22,SMURF1,SMARCA5,DNAJC8,AR,PIP4K2C |
| 3.830e-05 | -10.17 | CXCL11 (C-X-C motif chemokine ligand 11) | protein interactions | 6373 | 25 | 17 | 19454 | 5460 |
CXCL9,CCL8,CXCL10,CCR3,CXCR3,CCL1,CXCL14,CCL25,SMARCB1,CCL21,DPP4,CXCL12,CCL20,XCL1,CCL24,CCL11,CCL5 |
| 3.830e-05 | -10.17 | C6orf47 (chromosome 6 open reading frame 47) | protein interactions | 57827 | 25 | 17 | 19454 | 5460 |
VAPB,MEST,DNAJB6,RAB5C,SELENOK,RBM17,OTULINL,SEC62,MAD2L1,TACR3,ACP2,RUSF1,ENO2,RABAC1,HSD17B11,SEC61B,RTN4 |
| 3.830e-05 | -10.17 | GRHPR (glyoxylate and hydroxypyruvate reductase) | protein interactions | 9380 | 97 | 46 | 19454 | 5460 |
NMRAL1,TXNL1,HSPA8,PRDX6,RTN4,SOD1,FOS,POLDIP2,NDUFAB1,LAP3,SPR,GSTP1,EIF4B,AKR1A1,ARCN1,IDH2,CDC7,GLTP,GTF2F1,ACOX1,ENO1,CLIC4,USP14,MYC,ACO2,CTSD,PMPCA,FXN,HINT2,SLC25A5,MPST,UFM1,HSPE1,ETFA,GLRX5,PGM1,CMPK1,ETFB,PIR,AKR1B1,GATD3,PPIA,HSP90AB1,GLO1,MOV10,AGR2 |
| 3.830e-05 | -10.17 | COX7A2 (cytochrome c oxidase subunit 7A2) | protein interactions | 1347 | 97 | 46 | 19454 | 5460 |
GOLGA7,PSMB10,DNAJC30,VDAC1,NDUFA4,MTMR2,PDHA1,NDUFS3,EZH2,APOO,SLC25A12,EGLN3,MYL12A,NDUFS8,PRNP,ATP6V1A,CORO1C,COX4I1,PHB1,UPK1A,AGR2,CSTA,HDAC6,DNLZ,PHB2,PDHB,NDUFS2,HSCB,HADHA,PMAIP1,ATP5MK,CYC1,ACACA,COX7B2,HSP90B1,FBXL19,TOMM22,UQCRQ,ACTB,ATP5F1B,PTPMT1,SEC61B,UQCRC2,VDAC2,RIOK2,COX6B1 |
| 3.842e-05 | -10.17 | UBAC2 (UBA domain containing 2) | protein interactions | 337867 | 161 | 69 | 19454 | 5460 |
TRIM23,NONO,UFD1,BAG3,TOMM40,APEX1,ATP6AP2,RPL10,APLNR,UBB,CLRN2,RHOJ,PTEN,ZMYM2,CALML5,LMBR1L,CCNF,CSNK1A1,TBC1D17,RPA2,CFTR,CDC42,SEC22B,TPT1,ATP6V1C1,CHRNA7,TSPAN5,SLC25A51,HSCB,EMC1,DERL1,SYVN1,EXD2,MIR182,DUSP9,RHOU,MME,PEX3,RHOG,HM13,ADIPOR2,SLC25A46,ATG9A,ERLIN1,RHOH,ARF6,TMED9,CAND1,COX4I1,PHB1,RAB35,KCNA2,PDHA1,SURF4,TMEM31,RPN1,ERLIN2,GDE1,TUBA1A,FAF2,TP53,ADORA1,SOCS2,FASTKD5,VDAC1,KRAS,EMC2,TSPAN17,GLUL |
| 3.843e-05 | -10.17 | HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11) | protein interactions | 51170 | 382 | 143 | 19454 | 5460 |
LEMD3,PDCL,USE1,SSR1,GOLGA5,SYS1,TMX4,SLC12A2,METTL14,LMNA,PLP2,UBA52,SEC22B,ARHGAP1,RABL3,TMEM209,TMEM167B,CERS2,YKT6,MTDH,SPCS2,RTN4,ORMDL1,FADS2,TEX264,TMX2,ATP1A1,ARFGAP3,SMPD2,HMOX2,GORASP2,CSGALNACT2,DEPDC1B,SEC63,SFRP4,DHRS13,COPE,CYBC1,ATL1,VAMP3,CCNF,LBR,UBIAD1,SNAP29,CCDC47,PREB,FKBP8,SLC6A8,SFT2D2,ADIPOQ,SRPRB,TMX3,YIF1A,UNC50,ERG28,STX18,STX8,RUSF1,NSDHL,OSBPL8,AGPAT1,SMIM12,ESYT1,TMEM42,POR,RAB23,HM13,ATP5MG,SLC25A46,DHRS7,EI24,TMEM199,LMAN1,SLC38A2,TMPO,DNAJC1,ANKRD46,ARL6IP5,CAMLG,PTPN1,SRPRA,HACD3,SIGMAR1,VAPB,OTULINL,SEC22A,SEC62,BET1,GOSR2,EHHADH,NOTCH2,PGRMC1,TOR1AIP2,STX7,UFL1,HSCB,TMEM203,VMP1,ZMPSTE24,SCFD1,LMNB1,RAB11A,TMEM38B,VEZT,ATP6AP2,ABHD12,REEP4,TVP23B,GPR89A,GGT7,CYB5R3,FAM177A1,ARF1,CYB5B,PLD3,TMEM14B,HDAC11,STIM1,VAMP2,RPN1,FAF2,NEU1,STBD1,MACO1,SACM1L,SAR1B,RETREG1,NUP42,RASGRP3,EMC8,SCD5,RINT1,C2CD2L,FAM241B,CDK5RAP3,DDRGK1,PTDSS1,PGS1,NUP35,CYB5A,STX5,GJA1,PHB1 |
| 3.843e-05 | -10.17 | HARS2 (histidyl-tRNA synthetase 2, mitochondrial) | protein interactions | 23438 | 184 | 77 | 19454 | 5460 |
RAF1,IMP3,IL1R2,MRPL11,MIR17,PDHA1,MOB3C,OSTM1,MRFAP1L1,HSPD1,NDUFA4,HAPSTR1,HSD17B8,HINT2,COX8A,KRAS,ATP5F1D,MRPS17,IMMP2L,VPS16,MIR16-2,MTRF1,GRSF1,MOV10,FAM174A,PFDN5,LAMP3,RHOG,ACOT6,PDYN,MIR34A,SDHB,MIR106B,SSBP1,KRR1,YBEY,FAHD1,GATD3,MIR141,NAA30,NUDT9,RPL35A,MIR9-1,MALSU1,PRKAB1,MIR34B,AGTRAP,HCST,MRPL12,MED23,RPA2,ACAA2,GTF2H5,MTRES1,SRARP,RPA3,AMACR,MIRLET7I,GFM1,HSCB,GPIHBP1,STX7,MRPS7,MIR29A,AUH,MTG2,CABCOCO1,TUFM,SMPD2,TFDP2,MIR145,PHF7,DNAJB6,BST2,TXN,MRPL23,PARL |
| 3.843e-05 | -10.17 | AGPS (alkylglycerone phosphate synthase) | protein interactions | 8540 | 184 | 77 | 19454 | 5460 |
MRPS23,PNPLA8,CNTROB,LMAN1,MDM2,PHYH,KCTD10,PEX13,NOP58,GNPAT,DECR2,CORO1C,PHB1,NDUFB8,POR,COPS5,ATG7,ACOT8,SAR1B,TOMM6,EMC8,G3BP1,EMC2,GNG5,GARRE1,SFXN1,TMEM87A,RAB1A,PDHA1,HDAC11,NDUFS3,NUDT19,EZH2,EEF2,CYB5R1,KIF1C,HSDL2,PREB,RAF1,CEP97,VIRMA,LGALS3,ACTB,ATP5F1B,CYB5R3,UQCRC2,OPTN,ACOX1,NRP1,EPHA2,CHORDC1,TUFM,HMOX2,ATP5F1A,GSTK1,MYC,NDUFB10,PHB2,PDHB,UCHL3,HSCB,HADHA,EP300,HSPA8,NCDN,DVL2,RPA3,SLC25A3,ATP5PO,NUDT12,RPA2,CDK7,UQCRC1,PRDX3,DHRS4,EHHADH,ATG16L1 |
| 3.873e-05 | -10.16 | POLR2D (RNA polymerase II subunit D) | protein interactions | 5433 | 144 | 63 | 19454 | 5460 |
ELOF1,SNRPA,SMARCD3,XRCC5,FTL,POLR1H,MED11,POLR1D,MED30,ZSCAN1,TPT1,PIH1D1,MED31,RPRD1B,WWP1,POLR3B,INTS10,POLR3H,POLR2F,GTF2F1,POLR2B,SRC,MED17,TRIM29,IRF1,MCM3,MYC,LMO2,MED22,PFDN2,POLR1B,RIT1,MED10,BRCA1,CPNE2,RPAP3,FAM168A,PDRG1,SSRP1,KRAS,EMX1,SEM1,DNAAF10,PSMB9,ACTR1A,RPAP2,SUPT5H,MED9,E2F4,POLR2D,POLR2C,POLR2G,GTF2B,RPRD1A,POLR2L,SNRPA1,POLR2I,TOP1,WWP2,MED4,MED21,MED27,MED29 |
| 3.877e-05 | -10.16 | NME1-NME2 (NME1-NME2 readthrough) | protein interactions | 654364 | 89 | 43 | 19454 | 5460 |
MRPS28,SNX12,ENO1,ENO2,UBB,LDHA,TAGLN2,SNX3,CFL2,CFL1,TUFM,LDHB,FKBP1B,OAT,FIS1,CALU,HSPA8,AKAP1,RPA3,SOD1,HSPA5,NME4,EEF1G,DDAH1,FKBP1A,AKR1A1,PIH1D1,RPA2,ADSS2,DSTN,AKR1B1,NME2,AK2,BAG2,IDH1,HINT1,TAGLN3,HSPD1,FKBP2,PPIF,UBE2V1,RAF1,NME1 |
| 3.877e-05 | -10.16 | UBE2B (ubiquitin conjugating enzyme E2 B) | protein interactions | 7320 | 89 | 43 | 19454 | 5460 |
MED31,ZRANB2,H2BC1,UBE2B,UBE2V1,MAP1LC3B,UBA52,TP53,AHCYL1,CPLX1,ABHD10,SKP1,RNF20,UBE2A,SRSF2,TTC1,PCNA,BIRC2,RNF167,NBN,ZYX,SERPINH1,CRMP1,CDKN1B,RC3H2,UBE2D1,CTNNB1,RNF40,CSK,PSMB2,CBX5,MDM2,UBE2L3,UBE2V2,SEC23A,TRIM45,ZMYM2,TYMS,DSTN,IGBP1,SRSF1,SRXN1,SSBP1 |
| 3.931e-05 | -10.14 | macroautophagy | biological process | GO:0016236 | 204 | 87 | 18204 | 5365 |
TBC1D5,BAG3,VPS16,TRAF6,VTA1,ATG4C,CTSD,RAB19,UFM1,TMEM74,PLAA,RIMOC1,BECN1,RETREG2,ATG3,RETREG3,TSG101,VIPAS39,UBXN2B,TAFAZZIN,HGS,MAP1LC3A,NSFL1C,EMC6,RAB1B,VAMP8,VPS28,UBXN6,FUNDC1,VPS39,GABARAP,VPS4B,STBD1,ATG16L1,LGALS8,DDRGK1,ATG4A,RAB33B,SNX14,TEX264,VAMP7,RAB33A,RAB2A,CTSK,VMP1,CHMP5,STX12,LIX1,SMURF1,ATG7,GABARAPL2,KLHL3,MTM1,PSEN1,ATG9A,CHMP4C,STX17,RETREG1,UFL1,MCOLN1,CHMP2A,TP53INP2,VTI1B,EI24,CHMP2B,RAB1A,PIM2,SNAPIN,GABARAPL1,MAP1LC3B,CHMP1B,SRC,RB1CC1,VPS33A,SQSTM1,WDR45,SNAP29,PHB2,TP53,RAB23,USP30,ATG101,TOM1,CHMP1A,VPS4A,LAMP2,TP53INP1 |
| 3.935e-05 | -10.14 | CCAR2 (cell cycle and apoptosis regulator 2) | protein interactions | 57805 | 324 | 124 | 19454 | 5460 |
TMPO,CDK9,MDM2,EEF1AKMT3,SNRNP70,USP15,COPS5,PPIL4,HDAC6,GAPDH,SUV39H1,TPM3,MEPCE,MAP1B,HSD17B10,PSMC3,KBTBD4,CDK4,EEF1A1,DUSP1,ADRM1,SRC,EAF2,VIRMA,CCNF,PSMA6,EIF4A3,PSMC5,RC3H2,ZBTB38,RBM7,UBE2H,GSTK1,CIAO1,AR,WDR3,HDAC3,SMC4,AATF,DVL2,BAP1,RPA3,SOD1,SIRT7,PRKCB,SQSTM1,CDK1,RPA2,METTL14,DYRK2,RARS1,HEXIM1,TPT1,CCND1,UBA52,EEF1E1,CDK7,CFTR,RPS10,HNRNPL,SUMO2,HSP90AB1,ANKRA2,RBM5,IKBKB,POU5F1,PSMD3,IFI16,HNRNPA1,XPO1,YWHAH,CPEB1,SIAH2,ACTR3B,USP30,HNRNPF,ASF1A,TRIM37,RAD21,HSPD1,EWSR1,TRIM21,RUVBL2,BAG2,PDIA6,UBE3A,EZH2,MOB3C,OTULIN,RAF1,PPP2R1A,TUBA1A,SOX2,MATR3,SNRNP40,TENT5C,NCKAP1,MAD2L2,PNMA1,CMTR1,FOXP3,PRMT5,YWHAZ,BRCA1,HSP90AA1,HTRA2,CREBBP,MYC,PSMA4,CUL3,FXR2,B9D2,PSMC1,TRIM52,POLA2,HDAC5,HSPA8,DCTN3,RAB5A,STK26,EP300,PPT1,RPL27A,DUSP14 |
| 3.953e-05 | -10.14 | RALGAPB (Ral GTPase activating protein non-catalytic subunit beta) | protein interactions | 57148 | 63 | 33 | 19454 | 5460 |
RND2,CDC42,DLG3,ACACA,SGIP1,RAB4A,MEA1,RAB9A,RHOU,STX7,FBXW7,LAMP3,YWHAH,ATG7,YWHAG,RALGAPA2,DNAJC5,LAMP2,RAB11A,YWHAB,RHOG,RHOB,YWHAZ,TMEM74,SLMAP,NKIRAS2,STX6,ESR2,VIRMA,GFOD1,HNRNPL,RHOH,RHOJ |
| 3.953e-05 | -10.14 | HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) | protein interactions | 3155 | 63 | 33 | 19454 | 5460 |
MS4A7,RNF126,CTDSP1,PIR,ETFB,HSCB,KGD4,ETFA,ADAMTS10,COX17,LSM12,HSD17B10,ATPAF2,RAB1A,CA2,COTL1,IKBKB,GSTO1,NTAQ1,TOMM40,PCCB,LYPLAL1,ACO2,RAB11A,DBT,ESD,AKR1C2,TXNDC12,GATD3,CCNF,GTF2B,CYB5R3,MGME1 |
| 3.953e-05 | -10.14 | FAM111A (FAM111 trypsin like peptidase A) | protein interactions | 63901 | 63 | 33 | 19454 | 5460 |
BRCA1,RPL10A,H1-1,CDC23,RPS2,RPL7A,ZNF668,CGAS,RPL13A,RPL35,PRNP,LYAR,HNRNPL,RPS10,RPL19,RPL10,SURF6,SRSF1,RPL8,SRP14,FGFBP1,PRKRA,RPLP0,TP53,SF3A1,RAF1,NCSTN,RPL4,NPM3,RPL28,RPL31,RPL3,RPL23A |
| 3.959e-05 | -10.14 | lactone metabolic process | biological process | GO:1901334 | 11 | 10 | 18204 | 5365 |
SLC2A3,AKR1A1,GCLC,AKR1B1,SLC2A1,RGN,GSTO2,ATP1A2,SLC23A2,GSTO1 |
| 3.959e-05 | -10.14 | L-ascorbic acid metabolic process | biological process | GO:0019852 | 11 | 10 | 18204 | 5365 |
SLC2A3,GCLC,AKR1A1,AKR1B1,SLC2A1,RGN,GSTO2,ATP1A2,SLC23A2,GSTO1 |
| 3.974e-05 | -10.13 | MCCC1 (methylcrotonyl-CoA carboxylase subunit 1) | protein interactions | 56922 | 164 | 70 | 19454 | 5460 |
TP53,KBTBD4,ABHD10,SAR1B,ARF4,ARL5B,HUWE1,PC,SOS2,HSD17B8,SLC25A10,HSPB1,DDX1,TRAF6,TMEM70,AGR2,CBR4,COMMD5,PFDN5,ISX,MALSU1,ARL4D,YBEY,ARL10,ACTA2,HDHD3,NAP1L5,ACACA,ACAA2,RPA2,METTL2A,DCTN4,LDHAL6B,CTBP1,DET1,CFTR,FBXL19,MX1,PPP1R8,SSBP2,DUSP14,STAU1,KDM1A,MAVS,NPB,HSPA8,ATPAF2,RPA3,MAIP1,DVL2,SCFD1,TRIM23,FAM83A,TUFM,PCCB,MRM2,PNPLA4,MTG2,MYC,DYRK1A,IREB2,LGALS3,NDN,MRPL23,PTEN,PHF21A,RNF208,CCNF,ARF1,UQCRC2 |
| 3.982e-05 | -10.13 | SLC15A3 (solute carrier family 15 member 3) | protein interactions | 51296 | 231 | 93 | 19454 | 5460 |
LMBRD2,ATP5PO,ARCN1,PGRMC1,TIMM13,PHB2,STAU1,HADHA,LAMTOR1,CKB,CUL2,HNRNPAB,ATP5F1B,TNPO3,CHP1,PIGK,VDAC2,SEC61B,RETREG3,SLC30A7,PTRH2,RPN1,SNRPE,PLD3,ERLIN2,TUBA1A,FAF2,ATP5F1D,VDAC1,PGAP4,CHCHD2,RAB18,SACM1L,SLC39A7,VPS4A,HAX1,STOML2,MDFI,XPO1,ERLIN1,PHB1,GJA1,EIF2B3,SEC22B,RABL3,COQ8B,ST7,SLC35E1,TRAM1,CERS2,MAIP1,PPM1G,DNAJC10,ATP1B3,OAT,XPOT,ATP1A1,CIAO1,NDUFB10,ATP5F1A,COPE,CTSB,TECR,TRIM27,SURF4,MLLT11,YTHDF2,IPO8,CCDC47,ATP5PB,LBR,HUWE1,ERLEC1,RIGI,MSH6,ATP5PF,TMX3,CLPB,COX5A,ATP5MG,EI24,ATP1B1,EIF2B5,DERL2,CAND1,ILVBL,ATP5PD,COX4I1,HACD3,AIFM1,TIMM8B,PTPN1,STT3A |
| 3.984e-05 | -10.13 | organelle localization | biological process | GO:0051640 | 535 | 200 | 18204 | 5365 |
STX16,STX11,TMED9,STK11,TRIM46,HDAC6,PREB,CDK5,STX1A,NSFL1C,RAB6A,NUF2,RAB11B,SYK,TMEM106B,RAB11A,YKT6,VMP1,MRGPRX2,MUL1,ARMCX3,XPO1,TBCCD1,VAPB,ARMC1,FEZ1,ESYT1,EXOC8,VAMP3,EXOC5,TRAPPC10,EXOC3,STX6,SNAP23,GJA1,CFTR,NEFL,LAMTOR1,RB1,UBXN2B,FBXW11,TRAPPC6A,TESK1,BORCS8,NUP62,EXOC2,SYBU,CDK9,ARL6,NHERF1,RPS15,PIK3CG,TRAPPC2L,TFEB,PIP4P1,ZBED3,PSEN2,CHMP1B,NDE1,MGARP,CHAMP1,ARHGAP21,VPS4A,SKA1,MEF2A,KIF3B,STX10,NOP9,MAP1S,NLGN1,CDC23,ARFGAP3,STX5,BLOC1S2,SKA2,PPFIA3,PAFAH1B1,ACTR2,BICD2,BLOC1S5,CCNB1,STX17,ARCN1,AP3S2,BORCS5,CHMP4C,CHMP5,YWHAZ,TERB2,STX12,MAPRE1,CUL3,RAN,BORCS7,MREG,TRAPPC4,NDC80,MKKS,PTGDS,TRAK2,AP1AR,RNF167,VPS4B,HSBP1,PEX13,VAMP8,KXD1,WASL,LMNA,MAP1B,SPC24,FGF10,CTNNB1,PPFIA2,KLHL12,PDCD10,KLC2,RAB3A,KIF1C,DLG1,LAT2,PICALM,TRAPPC3,BECN1,CBL,KIT,BUB3,ENKD1,SKA3,ABCE1,TUBA1A,RAB27A,WDR11,COPS5,CHGA,CTBP1,CPLX2,FAM91A1,CAV2,STX7,ACTN4,TSG101,MAD2L1,STXBP1,MCPH1,TFG,HPS6,MIS12,MAP4,SNAP25,CFL1,SNAP91,SNAP29,LMNB1,STX8,SYNDIG1,BVES,SPRY1,PSRC1,VPS33A,TRAPPC13,CHMP1A,GNAO1,UBB,CEP19,ASPM,CDC42,AHCYL1,FLCN,BORCS6,ZNF207,BBS5,DYNC1I1,KCNB1,TRAPPC1,MTM1,PSEN1,SYT4,FAM98A,CCDC186,DSN1,MFN1,UBE2B,EXOC1,HDAC3,DNM2,CAV3,SYN3,VTI1B,RAB1A,CHMP2B,VPS18,BLOC1S3,SNAPIN,TRAPPC6B,SAR1B,STARD3NL,CDR2L,PAX6,CHMP2A |
| 3.985e-05 | -10.13 | RHOT2 (ras homolog family member T2) | protein interactions | 89941 | 318 | 122 | 19454 | 5460 |
CUL3,MYC,VEZT,SPCS3,ILK,RPS26,SCFD1,NTRK3,KLK5,FIS1,LMBR1L,SARM1,RMDN3,FAM83B,RANBP6,MAD2L2,ATP6AP2,APEX1,CHCHD3,APLNR,MTX2,TOMM22,TIMM29,TSHR,ARMCX3,VAPB,EXD2,RAB5A,AKAP1,PHB2,EMC1,HSCB,FBXL4,PXMP2,ARMCX2,PTPN5,MARCHF5,DDRGK1,RHOG,HAX1,PHB1,RPL9,C2CD4C,STX5,COX14,NDUFS8,EGLN3,TOP3B,STBD1,MACO1,B3GNT2,EEF2,FAF2,CHMP4C,PTRH2,STIM1,RPN1,CYB5B,TMEM14B,BCKDK,SCYL2,HNRNPF,EMC8,USP30,C9orf72,ARFGAP3,CHCHD4,PPTC7,CISD1,NRP1,EIF4A3,CCNF,CHMP5,MGST3,VIRMA,TECR,SEC22B,TIMMDC1,RABL3,CDC42,SAMM50,VIPAS39,LEMD3,PDCL,RAB29,RPA3,MTDH,MAVS,YKT6,TMEM209,MRPL20,BNIP3L,TOMM20,SLC25A46,FNDC11,COPS5,SMIM12,ESYT1,RPS2,EHBP1,CAMLG,PTPN1,AIFM1,TRAK2,CDCA3,LMAN1,FUNDC2,TNRC6C,MTCH2,SNAP29,CCDC47,PREB,MGARP,NDUFS3,DHX9,EMC2,RAB13,RAB3B,NUP107,FKBP8,VTA1,FKRP |
| 3.993e-05 | -10.13 | ANKRD49 (ankyrin repeat domain 49) | protein interactions | 54851 | 53 | 29 | 19454 | 5460 |
ROCK1,FKBPL,RIT1,FAM107A,STK24,PKNOX1,BTF3L4,CMSS1,MOV10,CMAS,ENKD1,ROCK2,KRAS,TCEA1,UBE3A,STK26,POLD2,PPP1R12A,LIN7C,BCL7B,PYM1,CSNK1A1,CHMP1A,QRSL1,CSNK1A1L,CFTR,CNPY3,CSNK1E,CPSF4 |
| 3.993e-05 | -10.13 | TRIAP1 (TP53 regulated inhibitor of apoptosis 1) | protein interactions | 51499 | 53 | 29 | 19454 | 5460 |
PRELID1,SH3BGRL,SLC25A12,PLGRKT,PARL,COX14,PLEKHF2,TXNDC12,AIFM1,COMT,CYB5R3,COX4I1,MED29,ELMOD2,AK3,ATG7,BAG3,LAMTOR2,KRAS,SLC25A51,COA4,PTRHD1,PEBP1,SFXN1,JCHAIN,CDC42,NDUFAF3,LYPLA1,TP53 |
| 4.001e-05 | -10.13 | regulation of tissue remodeling | biological process | GO:0034103 | 88 | 44 | 18204 | 5365 |
MIR214,MIR17,MIR20A,RUNX1,CD38,PRKCA,GJA1,GPNMB,IL2,PPARG,CARTPT,IL15,MIR16-1,MIR195,IL23A,UBASH3B,PPP3CA,IL18,SYK,SPP1,SRC,MIR34C,LEP,GREM1,TMBIM1,GPR137,HAND2,MIR34B,CST3,IL12B,TP53,ROCK2,SFRP1,IL21,CSK,IL6,ROCK1,TNFAIP3,MIR143,TFRC,MIR34A,TF,LEPR,BGLAP |
| 4.013e-05 | -10.12 | CPLX4 (complexin 4) | protein interactions | 339302 | 108 | 50 | 19454 | 5460 |
ORMDL1,SLC39A9,TMEM203,TMEM243,TMEM254,HACD1,HSPA8,SEC22B,AGTRAP,EFHD1,CTXN3,PLP2,GRM2,SMCO4,CDIPT,TMEM229B,CYBC1,CBX5,VAMP5,SLC35B4,PLN,STX8,GAD2,TF,ADIPOQ,TMEM60,PGAP2,SELENOK,INSIG2,NRM,UBIAD1,SFTPC,CTSA,TMEM14B,CYB5B,ACTA2,TRAF3IP3,TMEM14A,AIG1,CNIH1,TMEM97,TSPO2,TMEM19,PLPP4,SLC38A7,SYNJ2BP,CD81,TMEM107,SLC35A1,TMEM42 |
| 4.013e-05 | -10.12 | FKBP1A (FKBP prolyl isomerase 1A) | protein interactions | 2280 | 108 | 50 | 19454 | 5460 |
PIR,NUDT19,ACVR1,PPIF,MSX2,ACVR1B,HSPE1,FKBP2,GSTT1,HINT1,HSD17B10,TAGLN3,NME2,FKBP4,DCAF11,DDT,TST,PPP3CA,PMM2,PPIB,MDM2,FABP5,CTBP1,GSTO2,FKBP1A,CDC42,YKT6,GPC1,TGFB1I1,PEBP1,BMPR1A,BAP1,RPA3,SOD1,NMRAL1,GPX4,PMAIP1,DCAF16,HSP90AA1,TOMM40,BAG3,TXN,TAGLN2,APEX1,CCNF,ENO2,ENO1,CMBL,SF3B4,RPS9 |
| 4.013e-05 | -10.12 | IPPK (inositol-pentakisphosphate 2-kinase) | protein interactions | 64768 | 108 | 50 | 19454 | 5460 |
SC5D,CD47,LGALS3,LRRC8A,ACP2,SMAD5,SELENOT,VAMP3,GPR89A,ADGRL3,SERINC1,RETREG3,SNX14,REEP6,VEZT,KDSR,SLC30A5,CSGALNACT2,LPAR1,CERS2,CERS6,ZDHHC17,TESC,TSPAN15,CXCR4,GOLGA5,LEMD3,PIGW,HACD2,RMND1,EXTL2,ARL10,GPR137,FAM241B,TMEM11,FITM2,CDK12,TMEM164,FAM241A,FAM20B,LPCAT3,SACM1L,ATP2B4,STX8,NDUFB5,TMEM87A,HAPSTR1,ENPP4,YIPF4,PCDH19 |
| 4.014e-05 | -10.12 | PRKCB (protein kinase C beta) | protein interactions | 5579 | 234 | 94 | 19454 | 5460 |
H2AJ,H2AX,LBR,RPL15,DDX42,BMPR2,SLC25A10,H2AC25,GABRB2,SLC16A1,HUWE1,H3C1,AKAP12,RBCK1,H2AC6,RIGI,H2BC14,CYTH2,H2AC14,TSEN34,SLC2A1,TIAM1,OSBPL8,H2AZ1,RB1,MDM2,COQ8B,UBA52,CNP,COX6C,H2BC11,CDK1,DRD3,H2AC7,PRKCA,LEMD3,DVL2,DDX46,PRKCB,H2BC12,DERL1,H2AC13,EIF4E,RGS2,AKT1,PTPN11,FBXO7,EIF2S2,GSK3A,HPF1,PRKCE,TECR,UBB,HSDL2,BAG2,KIT,RASGRP3,NRGN,CCAR1,HNRNPDL,DDX50,YWHAG,CISH,IKBKB,LST1,HSPB1,PPP2CB,GJA1,SPTAN1,CCAR2,RPL27A,H1-5,STXBP1,ETF1,SDC2,APOBEC3C,ANXA7,ARCN1,PEBP1,EP300,SRSF2,GABRG2,MLF2,BLVRA,RPS6KA4,LMNB1,H2AZ2,HSP90AA1,H1-1,PELO,STAT1,TAMM41,TVP23B,GNB1 |
| 4.026e-05 | -10.12 | regulation of lymphocyte activation | biological process | GO:0051249 | 505 | 190 | 18204 | 5365 |
BAD,IL5,JAK2,PLA2G5,TIRAP,IL2,TGFBR2,EFNB1,MIR130A,SOD1,KLRD1,DLG1,XBP1,TNFSF13,CCL21,NDFIP1,TNFAIP3,FGF10,CTNNB1,SHLD1,NCK1,TOX,IL2RG,EP300,IGF1,CD209,DUSP3,IL1A,CCR7,STAT6,TNFSF18,PPP3CA,PTPN22,AKT1,IL1B,BLOC1S3,CD28,CD80,CBFB,MEF2C,MAD2L2,CAV1,IFNB1,TYROBP,RC3H2,WNT10B,CD46,INHA,MIR30B,IFNA2,MIR21,CD4,LILRB4,CD81,SMARCD3,TNFRSF1B,TLR9,IL20RB,SOCS5,RUNX1,MYD88,TACR1,ZBTB16,IL4,LST1,CSK,SFRP1,IL6,CD86,CCL5,FGR,MIR185,SOS2,SLC7A1,MMP14,IL12B,IL6ST,PRNP,BTN2A2,SMARCE1,PELI1,TNFSF8,KLHL25,ACTL6A,SASH3,JUNB,CD83,PNP,MIF,FOXP3,IL12A,CD274,BCL10,HSPD1,LILRB1,DHPS,ARG2,IL15RA,RAG1,TBC1D10C,CGAS,TNFRSF14,IL2RA,ICOS,CCL2,CDKN1A,DPP4,CCR2,IRF4,SFTPD,CCL19,AIF1,PDCD1LG2,CYRIB,CTLA4,RHOH,CD38,NLRP3,TRAF6,TESPA1,KLRC2,RHBDD3,GPAM,KMT5B,RPS3,SELENOK,TFRC,YES1,ACTB,TWSG1,CD2,VSIR,SLC39A10,XCL1,IL10,DUSP22,FCGR2B,PYCARD,AGER,DUSP10,MZB1,BATF,HMGB1,CD1D,SYK,HFE,BCL6,CD40,IL23A,B2M,IL7,DROSHA,CHRNB2,EXOSC3,LGALS3,HMCES,IL15,FBXO7,EPO,TICAM1,MIR181C,SIT1,PRELID1,SMARCB1,TNFRSF9,TNFAIP8L2,IRF1,GPNMB,PRKCQ,CLEC7A,IL21,IL13,ACTL6B,CD47,PIK3CA,SDC4,IDO1,IFNG,PTPN11,FGL2,THY1,CD40LG,LEP,RNF41,TLR4,NKAP,PRDX2,RAC2,IL18,SRC |
| 4.039e-05 | -10.12 | cellular response to molecule of bacterial origin | biological process | GO:0071219 | 221 | 93 | 18204 | 5365 |
MIR21,CDC73,MIR146A,CXCL3,CXCL13,OPRK1,CAPN2,MIR342,MYD88,IRAK4,CHMP5,TLR9,TNFRSF1B,TSPO,GFI1,MEF2C,LDOC1,CD80,CD36,TLR1,TICAM1,MIR140,PDE4B,TLR4,CSF2,IRF3,BCL10,SRC,CD274,LILRB1,MMP9,CAMP,CD86,PDCD4,IL6,DEFB124,IL12B,CXCL9,CXCL8,MIR223,CYRIB,PDCD1LG2,LITAF,CDK4,PLAA,TLR2,CD14,NLRP3,TRAF6,CCR5,TLR10,TICAM2,XBP1,MIR20A,MIR17,NFKB1,MRC1,PRKCE,HDAC5,IRF8,MIR105-1,MIR187,TIRAP,CXCL10,JAK2,CCL2,MTDH,CXCL1,PYCARD,STAP1,SELENOS,NFKBIL1,FCGR2B,TLR6,AKT1,IL1B,CD40,CEBPE,HMGB1,PTPN22,NFKBIB,CXCL11,LY96,TNFAIP3,GSTP1,CX3CR1,PLSCR4,MAP2K3,IL1A,IL10,NFKBIA,PLSCR3,TNF |
| 4.042e-05 | -10.12 | Electron Transport Chain | WikiPathways | WP111 | 92 | 52 | 5310 | 1910 |
COX7A1,NDUFAB1,NDUFS6,NDUFS8,COX6A2,ATP5PB,ATP5F1E,UQCRQ,ATP5PF,COX7B,ATP5MC3,NDUFV2,ATP5F1D,COX11,ATP5F1B,NDUFB6,COX8A,ATP5F1A,ATP5MC1,ATP5MG,ATP5PO,NDUFA4,SDHC,COX4I1,COX6C,NDUFB4,ATP5PD,SLC25A5,UQCRC2,NDUFS3,COX17,SDHB,UCP2,NDUFB5,SLC25A27,COX6B1,NDUFA2,NDUFA12,SLC25A4,UQCR11,NDUFS2,NDUFA1,NDUFA5,NDUFB8,NDUFC2,NDUFB10,COX5A,ATP5IF1,SLC25A14,UQCRH,UQCRC1,NDUFB7 |
| 4.048e-05 | -10.11 | regulation of defense response to virus | biological process | GO:0050688 | 63 | 34 | 18204 | 5365 |
TRAF3IP2,IL23A,TNFAIP3,CGAS,SELENOK,TRIM6,APOBEC3G,CCDC92,NT5C2,IL15,RIGI,SIN3A,MAVS,STAT1,TRIM44,IL12B,PPM1B,MUL1,TOMM70,MICB,APOBEC3F,HSP90AA1,FGL2,PYCARD,RNF26,TRIM22,MIR26B,ZMPSTE24,DHX9,FOXP3,PQBP1,ELMOD2,IL1B,LILRB1 |
| 4.095e-05 | -10.10 | antiviral innate immune response | biological process | GO:0140374 | 51 | 29 | 18204 | 5365 |
NLRP1,MBL2,IFIH1,MX1,EIF2AK2,TRAF6,DHX16,PHB2,UAP1,HCFC2,UBE2N,TBK1,AKAP1,TNF,UBE2W,NLRP6,RIGI,IFIT2,CXCL10,DHX15,CLPB,MAVS,PRKRA,NMBR,PHB1,NCK1,OAS1,TRIM6,PDE12 |
| 4.095e-05 | -10.10 | canonical NF-kappaB signal transduction | biological process | GO:0007249 | 51 | 29 | 18204 | 5365 |
TRIM8,BIRC2,NFKB1,NKIRAS2,MAP3K14,ROCK1,ROCK2,IKBKB,IRAK1BP1,DEFB124,TLR3,TLR7,PRDX4,EP300,NFKBIA,TANK,MIR146A,TLR4,TBK1,TIFA,TLR8,NFKBIL1,HACD3,TRAF6,NKIRAS1,AKT1,TLR2,PRDX1,TLR9 |
| 4.095e-05 | -10.10 | positive regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001238 | 51 | 29 | 18204 | 5365 |
TNFSF12,HTRA2,BCL10,CTNNA1,PPP2R1A,PAK2,LTBR,TLR6,ATF3,STK3,TLR4,PYCARD,TNF,TNFSF10,CAV1,PEA15,BMPR1B,STK4,RBCK1,PML,HYAL2,SFRP1,TRAF2,FAF1,LTB,PMAIP1,MIR198,G0S2,PDIA3 |
| 4.103e-05 | -10.10 | FAM9B (family with sequence similarity 9 member B) | protein interactions | 171483 | 167 | 71 | 19454 | 5460 |
STK3,RMND1,SURF6,LYRM2,PHYH,PPP1R18,GFOD1,TSG101,CEP57L1,RPL9,RPRD1A,DNAJC4,CDC23,LBX1,CENPL,ACP6,MRPL9,NOL4,RBM17,UBE2E2,ZCCHC10,FNDC11,SMN1,AP1M1,CDCA7L,POLL,SSNA1,BLOC1S2,HAPSTR1,TCEA2,TBC1D4,RNF8,SMARCB1,PPARA,AURKAIP1,SNX20,SNAP29,FCHSD2,RSL24D1,MYG1,GPX1,TBC1D25,CHRAC1,PSMD14,FERD3L,SLPI,EIF3G,TBC1D1,TUFM,SFN,MORF4L1,GSTK1,NDUFB10,BCL2A1,CDC42EP4,CDSN,CMTM6,CCDC106,MNS1,RBM23,MFAP1,SDCBP,LMNA,RPRD1B,TOM1L2,MRPL10,DENND2D,ISCU,BET1,FAM161A,NDE1 |
| 4.140e-05 | -10.09 | CEP170 (centrosomal protein 170) | protein interactions | 9859 | 294 | 114 | 19454 | 5460 |
RPA2,SDCBP,SCLT1,HECTD1,HAUS2,LUC7L3,ATG16L1,CFTR,GTF2I,FBXW7,OIP5,RPA3,BAP1,SIRT7,PML,TRIM10,GPX4,SQSTM1,PEA15,UBE2H,MAPRE1,EMILIN1,CCNB1,MTPN,NDN,DAPK3,RPGRIP1L,SRPK2,VIRMA,CCNF,PSPC1,SMAP2,CSNK2B,PTEN,ACTR2,DISC1,KBTBD4,TMSB10,MAP2K3,NECAP2,TFPT,STX8,SNRNP70,SHC1,MAP4,KLHL9,CSNK2A1,VTI1B,SLAIN2,SURF6,NELL2,TNKS,MTAP,COX20,VAV2,CSNK1A1,INPP5E,MTMR6,BORCS6,PPP2R3A,UFL1,STAU1,UNC45A,LCA5,HSPA8,BRCA1,YWHAZ,SETD7,MYC,SFN,CUL3,BTF3,MB21D2,ESR2,IRF2,CYB5R3,TUBB4B,SKA3,PNMA2,CRKL,RAF1,B3GNT2,SOX2,SNAPIN,KIF2A,DSTYK,LASP1,TRIM37,VAMP8,MRFAP1L1,BAG2,UBE3A,SKA1,DRG2,NCK1,ASB7,CBL,RB1CC1,MED4,YWHAB,IFI16,YWHAH,YWHAG,XPO1,INSYN1,DDRGK1,HNRNPL,OCRL,CCAR2,KCTD10,EGLN3,CEP19,PHB1,SNX17 |
| 4.164e-05 | -10.09 | DDX27 (DEAD-box helicase 27) | protein interactions | 55661 | 288 | 112 | 19454 | 5460 |
KLF12,RPS14,RPLP0,GRM2,RPA2,MTDH,RNF113A,NLE1,SIRT7,RPA3,UTP23,RPL4,DGCR8,NPM3,RPL26,RPL7A,UBE2H,ATP1A1,PRKRA,FGFBP1,EIF2AK2,ZNF330,CCNF,RPL22,SRPK2,SMURF1,RHOJ,RPL13A,AURKAIP1,TP53,RPSA,SRP72,HBP1,RBM34,RPL23A,RPL3,DDR1,SNIP1,RPL17,TGFBR2,H3C1,E4F1,API5,GRSF1,RPL10A,RPS2,NOL12,H2AC4,KRR1,SYNCRIP,SURF6,KLF9,TOMM70,CDK9,DKC1,CGAS,FZR1,RPS16,MTF1,SYK,H1-5,APOBEC3C,EP300,STAU1,NOP53,ZNF692,ZNF668,RAB11A,MYC,H1-1,DNAJB6,FTSJ3,PPP1R16A,RPS9,RPL37A,APEX1,RPL10,RPL19,SNRNP40,RPL35,RPL7L1,SOX2,MAK16,RAF1,RPL18,CHMP4C,HDAC11,RPS24,PPAN,RPL31,RPL28,SRSF4,ASF1A,HMGN4,RUVBL1,H1-6,KRAS,DDRGK1,YWHAG,WWP2,IFI16,RPL23,LHX2,DDX23,WDR12,EED,SRSF1,RPL9,RPL8,LYAR,RPS10,NOP58 |
| 4.173e-05 | -10.08 | AGRN (agrin) | protein interactions | 375790 | 258 | 102 | 19454 | 5460 |
PGAM1,MOV10,TPM3,DAG1,TUBG1,SPP1,CCL4L1,ELSPBP1,SEC23A,RPS27L,THOC1,PGM1,DISC1,TNNI1,SRP72,MAP1B,PC,HNRNPK,CTNNBL1,CAMKV,OLFM3,SUGP1,CHCHD4,SDF2L1,SNX14,TUBA1B,TMSB4X,ENO1,FBLN5,RPS3,GTF2A1,LDHA,PYGM,RPL22,VIRMA,MYL12B,PIP5K1A,CCL3,CZIB,HSP90B1,OSER1,DVL2,H2AC13,ARMCX5,AIF1L,ZC3H15,CFC1,MAP1S,PDIA3,HMGA1,TENM3,STK4,HNRNPA1,AGR2,HSPB1,ABITRAM,BOLL,COPS2,SPTAN1,DNAJB9,OS9,HSP90AB1,RANBP1,NAA15,TOP3B,MAX,PI15,CBLN4,EEF2,ACTN4,H2BC1,RPN1,EZH2,ZRANB2,PABPC1,FSTL1,TRIM11,EWSR1,TRIM21,SLC39A7,SACM1L,RFC3,HNRNPAB,CUL3,MYC,CKB,PRSS1,PAXX,TUBB,EIF4A2,PSMD4,ACAP2,B4GAT1,ESR2,PGRMC1,RRAGA,NUFIP2,OLFML3,HADHA,DDX5,HSPA8,NSFL1C |
| 4.178e-05 | -10.08 | BLK (BLK proto-oncogene, Src family tyrosine kinase) | protein interactions | 640 | 196 | 81 | 19454 | 5460 |
ATP5IF1,BIRC2,TLR2,ATP5F1E,CXCR4,JAKMIP1,CNKSR3,ATP5MK,HSPA5,FXR2,PHB2,YTHDF1,GLRA2,EEF1E1,HEXIM1,MET,ZBTB42,CSNK1A1,CDK1,ATP5PO,ZMYM6,HSP90B1,RPL37A,SNRPD1,GAB1,CINP,CD79B,GNG12,SRC,BTG3,ATP5F1B,TUBB,ATP5F1A,FBXO7,SKAP2,AR,PIK3R3,HNRNPC,GRB10,HSP90AA1,CDKN2AIP,CCT2,DNAJC10,PICK1,UBE3A,LRTM2,ATP5PF,CCT8,EDEM2,CTNND1,APBB3,ARL5B,KIT,CNOT7,ATP5F1D,SOCS3,DNAJC25,NCSTN,ISG15,TULP3,EEF2,ATP5PB,CCT5,CRKL,SSBP3,CAMK1,TLR3,AIP,ATP5PD,HSP90AB1,CCT7,FCGR2B,FCGR2A,GAPDH,MTRF1,PIK3R1,ATP5MG,CBL,CDC23,BCL2L1,HSPB1 |
| 4.183e-05 | -10.08 | DCTN1 (dynactin subunit 1) | protein interactions | 1639 | 457 | 167 | 19454 | 5460 |
STK24,BICD2,BMERB1,MAPRE1,UBE2H,SNX5,AKT1,RAB2A,GSTK1,CCNB1,MTPN,ARHGAP21,ZNF622,GPX1,CEP41,SNX3,SMURF1,VIRMA,CCSER2,GANAB,RPA2,DCTN4,UBE2M,HEXIM1,TRIM36,HECTD1,SPTBN1,SAP30BP,FAM161A,EDF1,UQCRC1,NEK2,CFTR,KDM1A,SMC4,FBXW7,ZC3H15,BAP1,RPA3,ZKSCAN1,IRF3,DCTN6,HSPB2,RNF113A,PSMD7,MAP4,USP15,RNF14,MOV10,PGAM1,ABRACL,HDAC6,FZR1,MAPRE2,ESD,SLAIN2,MAP2K6,ACTA2,TES,SEC23A,DISC1,CAPZA2,RNF181,YTHDF2,IPO8,MAP2K3,ACTR1A,MAP1LC3B,EEF1A1,DYNC1I1,KPNA2,MEPCE,RIGI,MSH6,CAPZA1,HAPSTR1,YWHAZ,PSMD14,MYO6,CHTOP,BRCA1,LSM14B,MYC,CUL3,BTF3,MCM3,MCM4,BAG3,PDLIM3,STAT1,MATR3,ACTB,TRIM29,DYNLL1,PSMB6,POLR2B,APEX1,ESR2,SKA2,PSRC1,NDUFA5,PAFAH1B1,RFXANK,GKAP1,RAB6A,TBCEL,SRSF2,UFL1,YTHDF1,STAU1,PACSIN3,FBXW4,SPECC1L,UPF3B,JAKMIP1,TMEM256,TXNL1,HSPA8,DCTN3,NUBP2,CFDP1,STK26,SPHK2,CAMSAP2,YWHAB,VPS26A,NDC80,MAP1S,YWHAH,TBC1D5,BTF3L4,EIF3D,DYNC1I2,SNX2,AGK,SNX1,HYPK,EGLN3,NUF2,RAB35,DNM2,SRSF1,FBXO32,SKA3,TUBB4B,EZH2,MTA2,MOB3C,NAA15,SPC24,TOP3B,KIAA0408,ERLIN2,DSTYK,LGR4,KIF2A,G3BP1,LASP1,TRIM26,CCAR1,MCM6,UBE2A,PFDN1,SDHC,ZC3H7A,ACTR1B,SKA1 |
| 4.190e-05 | -10.08 | E6 (early protein) | protein interactions | 1489480 | 34 | 21 | 19454 | 5460 |
RFC2,RPL10,PPIA,IL18,CHCHD2,RNF10,PSMB1,PSMB5,IRF3,SMAD3,SMAD2,TADA3,TFDP2,POMP,CDKN1A,COPS5,SIPA1L1,TPT1,ATF4,RPSA,CCNB1 |
| 4.190e-05 | -10.08 | FOXO4 (forkhead box O4) | protein interactions | 4303 | 34 | 21 | 19454 | 5460 |
AKT2,S100B,SMAD3,MDM2,CREBBP,FEN1,AKT1,VDR,TP53,CCND1,SFN,YWHAG,FBXO7,XPO1,YWHAH,CDKN1A,CTNNB1,SMAD4,YWHAZ,COP1,YWHAB |
| 4.194e-05 | -10.08 | KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1) | protein interactions | 10657 | 358 | 135 | 19454 | 5460 |
WDR77,PPP1CB,PALS2,PSMB7,SNRPA,GPHN,CRY1,HSPA8,MIA2,EMG1,DDX5,EP300,FXR2,UFL1,PSMC1,PACSIN3,MYC,CREBBP,RUSC2,PSMA4,HNRNPC,CUL3,PIK3R3,BTF3,SNRPB,CIRBP,PSMD14,FBXW11,BRCA1,DLG4,MATR3,ACTB,SNRNP40,PSMD6,TENT5C,PSMB6,B3GNT2,DLG3,DHX38,NCSTN,SOX2,LGR4,TNPO2,PIR,GLE1,EZH2,NGB,MTA2,CRKL,EWSR1,RUVBL2,UBE3A,KIT,SSRP1,CBLL1,PIK3R1,WWP2,HNRNPA1,DDRGK1,CTNNB1,AGR2,DROSHA,NCK1,HNRNPD,CBL,SIN3A,PSMB5,PHB1,AZIN1,COPS2,HNRNPL,DHX15,RBFOX2,ATG16L1,UBA52,CDC42,AGO1,CD2AP,CFTR,TRIM68,CDK1,RPA2,GRM2,UBE2M,BAP1,RPA3,CLK1,KDM1A,CSK,SKAP2,PPP1CC,SPOP,RC3H2,SMAD2,NCKIPSD,RBM7,UBE2H,STUB1,SRP54,GSK3A,MOB4,UBASH3B,YES1,SRC,VIRMA,SRPK2,FBP1,WBP11,GGTA1,DUSP1,DISC1,GRAP2,PSMC3,RNF181,RAB1A,FAF1,PSME1,DLG1,DHX9,HNRNPK,CD81,GRAP,HDAC6,SNRNP70,FGR,USP15,ITK,SYNCRIP,SCG5,RCHY1,DCUN1D1,FZR1,CAND1,TOP1,CDC5L |
| 4.215e-05 | -10.07 | OPRL1 (opioid related nociceptin receptor 1) | protein interactions | 4987 | 100 | 47 | 19454 | 5460 |
NDUFB5,ATP2B4,RINT1,SLC25A14,LPCAT3,PGAP4,DNAJC30,SLC20A2,DDX39A,METTL15,ATP5PB,ENPP4,TSPAN3,SLC25A24,ACSL4,RAB39B,ATP5PD,TLCD4,SPPL3,HNRNPL,ADCK1,FAM241A,ATP5MG,TMEM164,DEGS1,SLC35F2,GNA14,TMEM126B,MGAT4B,RGS19,CERS6,CERS2,HACD2,ADIPOR1,SLC19A2,TM9SF1,LMBRD2,ATP5PO,PTEN,METAP2,ATP5F1B,ACTB,ATP5F1A,ST3GAL2,PNOC,OPRM1,ATP1A3 |
| 4.221e-05 | -10.07 | CCDC102B (coiled-coil domain containing 102B) | protein interactions | 79839 | 150 | 65 | 19454 | 5460 |
CDK1,SDCBP,TFIP11,MFAP1,RARS1,ZBTB42,ATG16L1,FAM161A,EHHADH,XBP1,LMO4,NME4,SGF29,DCTN6,CCDC86,NIF3L1,ARFGAP3,CCHCR1,SNX5,ZNF250,CACNB4,SFN,FBXO7,EXOC5,NTAQ1,TTC23,MAGOHB,TRIM54,ZNF622,TAB1,PSMD6,TRIM27,SRP54,TNNI1,DISC1,TAB2,ARL4A,PNMA5,SNAPIN,POP5,MSX2,SPG21,PSMA1,RAD21,ENKD1,FLOT1,PICK1,VPS26B,NXT2,TRAPPC4,ZNF688,FNDC11,TPM3,SPATA2,EDC3,PPP1R18,SNX1,PRPF18,TRAPPC6B,CEP19,CEP57L1,ARL4D,RGP1,TRAPPC3,TRAPPC10 |
| 4.221e-05 | -10.07 | TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1) | protein interactions | 7073 | 150 | 65 | 19454 | 5460 |
PIR,MIR20A,EZH2,NUPR1,RAF1,KIF2A,SOX2,VDAC1,MAPK1IP1L,G3BP1,UFM1,NEDD8,RNF26,RIGI,MIR9-2,GADD45A,PABPC1,FAM168A,SNRNP70,COTL1,MIR34A,AKAP8L,POU5F1,SAV1,COPS5,XPO1,MIR29C,DCUN1D1,CAND1,KLF1,INA,FUBP3,PHB1,SSBP1,MIR106B,THY1,ACAA2,EMC9,RPA2,PRR13,KRTAP8-1,SRI,HSCB,MIR29A,MIR106A,FAM168B,SNRPA,PTRHD1,RPA3,SOD1,MIR145,BRCA1,CUL2,CUL3,CREBBP,MYC,TOMM40,FBXO22,APEX1,PRRC2A,ESR2,MRPL53,CCNF,MRPS28,SF3B4 |
| 4.221e-05 | -10.07 | DSC2 (desmocollin 2) | protein interactions | 1824 | 150 | 65 | 19454 | 5460 |
STX7,RHOU,RAB5A,DERL1,RAB9A,SLC35F2,CLK1,JUP,CLDN4,RND2,TMEM106A,OTULINL,CDC42,SEC62,RHOJ,GXYLT1,LMBR1L,SEC61B,TRIM24,RHOB,CMA1,YWHAZ,SDF2L1,LAMTOR1,CSGALNACT1,EPHA2,LILRA3,SFN,RAB11A,RAB2A,DNAJC5,EPHA4,KRAS,FLOT1,TMT1A,SKA1,NTRK2,RPN1,RND3,SOX2,CLEC2B,RHOH,ARF6,CAV1,LMAN1,DIRAS3,CD1A,STX6,EEF1AKMT3,RAB35,HRAS,ARL4D,RAC2,NRSN1,GJA1,HSD17B11,RHOG,TNFSF13,BRD3,YWHAB,STYK1,CFC1,LAMP2,YWHAH,YWHAG |
| 4.228e-05 | -10.07 | BZW1 (basic leucine zipper and W2 domains 1) | protein interactions | 9689 | 170 | 72 | 19454 | 5460 |
LDHA,SNRNP40,PSMD6,RHOJ,ADRM1,RBBP4,ESR2,LMBR1L,SNRPD1,SF3B4,PRMT5,SNRPD2,GPR17,RAB11A,LDHB,PSMD1,PRPF31,KPNA6,SRSF2,HSCB,NF2,SMC4,SNRPA,BAP1,RPA3,TXNL1,HSPA8,SF3B1,SQSTM1,EP300,VAV2,RPA2,STOM,FKBP10,EIF4B,HECTD1,ETF1,DUSP22,SNRPA1,SNRPD3,SUMO2,SRSF10,CDC5L,CWC15,CD274,SRSF1,LDLR,SNRNP70,AGR2,USP15,PSMD3,PRPF19,EDEM1,PTPN5,PSMA1,HNRNPF,CD80,RUVBL1,SAR1B,RUVBL2,HSD17B10,KDELR1,BZW2,ILF2,MTA2,GNAI3,MOB3C,COMTD1,ACTR1A,ZMYM3,EEF2,TNPO2 |
| 4.241e-05 | -10.07 | PRDM4 (PR/SET domain 4) | protein interactions | 11108 | 23 | 16 | 19454 | 5460 |
EMX1,SERTAD1,HDAC3,CTNNBL1,STK38,DBT,EIF4E,ERH,APEX1,DYRK1A,SMAD3,PRDM4,MSRB3,RUNX1,NT5C2,CFTR |
| 4.277e-05 | -10.06 | GST_CTER | prosite domains | PS50405 | 32 | 20 | 12186 | 3388 |
GSTM3,GSTT2B,GSTM4,HPGDS,GSTP1,GSTA2,GSTO2,GSTCD,GSTA4,MARS1,GDAP1L1,EEF1E1,GSTM2,GSTO1,GSTA1,GSTT1,GSTM5,CLIC4,EEF1G,CLIC2 |
| 4.297e-05 | -10.06 | DUSP6 (dual specificity phosphatase 6) | protein interactions | 1848 | 122 | 55 | 19454 | 5460 |
TMEM11,VPS4A,HSPB1,MDFI,RAB5C,ADIPOR2,QPCTL,CAND1,NKIRAS2,TMEM97,GLT8D1,GTF2B,SRPRA,COX4I1,UBE2G2,DUSP6,RP9,PTRH2,ARPC3,GNAI3,TMEM126A,MGARP,G3BP1,TRIM37,SRPRB,RIGI,CCT8,MAEA,RAB13,TMX3,TRIM11,CCT2,OAT,MAT2A,RPL39,MBLAC2,RAB14,HDDC2,TIMM21,CHP1,GNAI2,NDUFAF4,SEC63,CYBC1,PTPMT1,FDFT1,TIMMDC1,SRM,PSMC1,G3BP2,HSPA5,UGDH,MAIP1,DUSP9,HSPA8 |
| 4.297e-05 | -10.06 | RTCA (RNA 3'-terminal phosphate cyclase) | protein interactions | 8634 | 122 | 55 | 19454 | 5460 |
MIR205,MIR10B,RPA3,MIR34C,MIRLET7I,HSCB,ATG16L1,MIR34B,CNTN2,FOXS1,RPA2,MIR7-1,MIR21,MIR16-1,MIRLET7B,MYC,MIR145,UBE2H,MIR363,MIR9-2,NDUFA4,BCKDK,OSTM1,MIR200A,RPL23A,MIR155,PAEP,MIR16-2,MIRLET7C,MIR15A,MIR222,MIR17,OTX2,EEF1AKMT3,MIR7-2,PHB1,ELSPBP1,MIR106B,MIR141,MIR214,MIR25,MIR9-1,MIRLET7G,FZR1,RPS10,CAND1,MIR429,MIR143,DDRGK1,LAMP3,MIR29C,MIR31,SNRNP70,CSTA,MIR1-1 |
| 4.319e-05 | -10.05 | VPS4A (vacuolar protein sorting 4 homolog A) | protein interactions | 27183 | 84 | 41 | 19454 | 5460 |
BAP1,RINT1,EP300,SRSF7,CHMP1B,IRF7,TRA2B,VTA1,KCND3,SEC22B,RND2,CFTR,VPS4B,CHMP4C,USE1,CHMP1A,ZNF574,HGS,CCNF,LMBR1L,DUSP6,PCBP4,COPE,CHMP5,CGAS,EGLN3,TMEM248,CHMP2A,MYC,CUL3,BABAM1,BTF3,PSMD1,RHEB,ATP1A3,LAMTOR1,ATG3,SNRNP70,VPS4A,THTPA,UBE2H |
| 4.319e-05 | -10.05 | SHMT1 (serine hydroxymethyltransferase 1) | protein interactions | 6470 | 84 | 41 | 19454 | 5460 |
STXBP1,SHMT1,ATP6V1C1,APEH,PRSS23,CHMP4C,GNPDA2,RPA2,ARFIP1,TTC1,EFNB1,HAPSTR1,RPA3,BAP1,HSPE1,STK38,HSCB,GORASP2,IFNAR1,FBXO7,CARS1,MDFI,NIBAN2,MCAT,DEDD,SPOP,SMAD4,GTF2F2,CSNK2B,XPO5,PBDC1,CTTN,CCNF,SULT1A3,IDE,IREB2,EGLN3,PPAT,TSN,SNX2,STAT1 |
| 4.329e-05 | -10.05 | NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11) | protein interactions | 54539 | 92 | 44 | 19454 | 5460 |
NDUFB8,RAB5C,FATE1,NDUFV2,SLC25A12,CYSTM1,NDUFS8,NDUFB4,COX4I1,AIFM1,SDHB,NDUFA1,NDUFS6,NDUFS3,SURF4,NDUFA12,NDUFA2,DNAJC30,GJB1,NDUFA4,SFXN1,NDUFB5,NDUFB6,NDUFB10,NDUFB7,LAMTOR3,ATP5F1B,VIRMA,PARL,APLNR,RPA2,VAPB,NDUFA5,TIMMDC1,NDUFAF3,NDUFAB1,SLC25A51,NDUFS2,HSCB,PIP4P1,TMEM185A,PMAIP1,TMEM126B,NDUFC2 |
| 4.329e-05 | -10.05 | ZNF770 (zinc finger protein 770) | protein interactions | 54989 | 92 | 44 | 19454 | 5460 |
MRPS34,APOBEC3C,RPLP0,MACROH2A2,RPL27A,FGF17,CFTR,DGCR8,RPL4,RNF113A,MRPS25,RPL7A,ZNF668,GGH,RPL35,RPL13A,RPL19,TNFRSF1B,RPL37A,PRKRA,FGFBP1,ZMYM2,RPS9,LLPH,RPL18,MRPS17,RPL28,RPL17,RPL31,PPAN,RPL3,MRPS18B,RPL23A,NOL12,RPS2,RPL10A,E4F1,RPS10,RPL7,LYAR,SURF6,RPL8,KRR1,PRR3 |
| 4.329e-05 | -10.05 | TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D) | protein interactions | 79101 | 92 | 44 | 19454 | 5460 |
PTN,NPM3,STAU1,RPL4,APOBEC3C,RPLP0,RPL26L1,RPS14,ING5,FGF13,RPL13A,LRIF1,DDAH2,SRPK2,TRIM44,TMSB4X,CSNK2B,FGFBP1,MCPH1,MECP2,POLR1B,RRN3,RPL7A,CEP70,RPL28,RPL17,RIGI,FAF1,PPAN,RPL3,RPL23A,EZH2,LLPH,RBM34,SMARCB1,RAF1,TAF1D,HSP90AB1,RPL8,FEZ1,UBE2D1,POLB,FAM20C,CSNK2A1 |
| 4.341e-05 | -10.04 | RSBN1L (round spermatid basic protein 1 like) | protein interactions | 222194 | 111 | 51 | 19454 | 5460 |
H3C1,SRSF4,RPL17,RPL31,RPL23A,CBX3,RBM34,ZRANB2,RAF1,RPS10,RPS16,LYAR,NKAP,RPL8,DDX23,SNRNP70,DRG2,RPS2,BRD3,IFI16,ZCCHC10,DDRGK1,FBXW7,COIL,ZDHHC17,PPM1G,APOBEC3C,RPLP0,RPL26L1,SNRNP40,DYNLL1,RPL13A,FBXO22,DYRK1A,APEX1,RPL22,ESR2,VIRMA,RPL19,PSPC1,RPS3,ZNF330,PRKRA,FGFBP1,PSMD14,ZBTB38,H1-1,MYC,RPL7A,ZNF668,SAMHD1 |
| 4.341e-05 | -10.04 | PDE12 (phosphodiesterase 12) | protein interactions | 201626 | 111 | 51 | 19454 | 5460 |
DNAJC19,BRCA1,SPOP,TUFM,FBXO7,CUL3,PMPCA,AUH,MTG2,MYC,APEX1,APEX2,LMBR1L,TACO1,CCNF,MTRES1,STAT6,RPA2,DHRS4,EHD1,DNLZ,STAU1,HSCB,GFM1,EP300,EXD2,RPA3,MRPS26,TMEM70,RHOG,SMAD4,COPS5,MTRF1,EGLN3,GATD3,ATP6V1A,SSBP1,RAD23B,PGGT1B,PDHA1,METTL15,MRPL11,TP53,UBL4A,IMMP2L,DCTPP1,XPNPEP1,CHCHD2,COX8A,HINT2,HSPD1 |
| 4.346e-05 | -10.04 | regulation of non-canonical NF-kappaB signal transduction | biological process | GO:1901222 | 109 | 52 | 18204 | 5365 |
IFI35,MIR149,CPNE1,CCL19,MIR21,LITAF,TRIM26,DLG1,TLR9,TLR2,EIF2AK2,NLRP3,IL23A,NLRP2,TLR7,RBCK1,MIR204,ACTN4,PPM1B,TRIM15,RC3H2,TRIM44,NMI,PHB2,AGER,PYCARD,GREM1,AKIP1,TLR4,ADIPOR1,PRDX1,MIR182,IL18,PTPN22,MIR132,IL1B,PDCD4,CCN3,CD86,PYDC2,PTP4A3,PHB1,BIRC2,MIR9-1,RPS3,TRIM6,TNF,MIR223,TLR3,TCIM,IL12B,CALR |
| 4.347e-05 | -10.04 | CASC3 (CASC3 exon junction complex subunit) | protein interactions | 22794 | 136 | 60 | 19454 | 5460 |
NUFIP2,RPLP0,LARP4B,RBMS2,PABPC5,SAP18,STAU1,NOP53,EP300,LSM12,NKAPD1,NBN,UPF3B,MCRIP2,PYM1,MAPRE1,ELAVL2,PAIP2,HNRNPC,MYC,AKT1,ESR2,PRRC2A,MAGOHB,EIF4A3,PSPC1,ILF2,PAIP2B,APOBEC3D,OTUD6B,YTHDF2,KIF1C,B3GNT2,RAF1,THRAP3,NUP42,SRSF7,EWSR1,ARGLU1,PABPC1,RBM3,SNIP1,MAGOH,YWHAB,SNRNP70,TRA2A,XPO1,YWHAG,YWHAH,GRSF1,HNRNPL,RPS16,VTI1B,PAIP1,CAND1,CDK6,SRSF1,ALYREF,PHB1,PTPN1 |
| 4.349e-05 | -10.04 | SLC7A5 (solute carrier family 7 member 5) | protein interactions | 8140 | 173 | 73 | 19454 | 5460 |
DNAJC5,RAB2A,RAB11A,ATP1A1,CDC73,RIT1,ATP1B3,LAMTOR1,RHOB,SEC61A1,ARF1,VIRMA,ESR2,RHOJ,RND2,CDC42,TOMM22,CLDN4,PGRMC1,BET1,CAV2,PIH1D1,RPA2,MAP2K1,HSPA8,RNF113A,PMAIP1,RAB5A,EP300,RAB9A,RPA3,RHOU,STX7,LAMP3,ATG9A,DPP4,LAMP2,RAB5C,RHOG,GJA1,TES,RAC2,HRAS,FOLR1,RAB35,PHB1,DIRAS3,ELK1,LMAN1,STX6,EGLN3,CAV1,ARF6,RHOH,NCSTN,LGR4,TOP3B,TP53,RND3,FURIN,PLD3,RPN1,CHMP4C,RAB4A,PTRH2,SLC16A1,TMX3,COX8A,MAP1B,FLOT1,H3C1,KRAS,RAB3B |
| 4.349e-05 | -10.04 | CCAR1 (cell division cycle and apoptosis regulator 1) | protein interactions | 55749 | 173 | 73 | 19454 | 5460 |
RB1,MIR106B,FUBP3,RBM5,MDM2,HSP90AB1,HNRNPL,CAND1,DYNC1I2,TOP1,COMMD6,MIRLET7G,HNRNPA1,TBC1D5,RBM17,MED4,SSX2IP,KPNA1,SNRNP70,PCNA,EMC2,FHL3,ACTR1B,ZYX,MEPCE,SSRP1,HNRNPK,TOLLIP,ACTR1A,ZNF263,MARCKSL1,BUD23,UBL4A,RAF1,E2F4,TP53,SNRPE,EZH2,CCNF,NFKBIB,SMURF1,SNRPB2,APEX1,SRPK2,VIRMA,PSMD4,SNRNP40,FBXO22,SNRPB,AR,MYC,CIAO1,SFN,CCNB1,HSP90AA1,UBE2H,H2AZ2,PRKCB,HSPA8,SF3B1,RNF113A,SNRPA,DDX46,RPA3,SIRT7,GRPEL1,CLU,AATF,STAU1,HMGB1,ATG16L1,SF3A1,RPA2 |
| 4.349e-05 | -10.04 | MYO1D (myosin ID) | protein interactions | 4642 | 173 | 73 | 19454 | 5460 |
FLOT1,MDC1,FBXO25,KRAS,PSMA1,TNF,ERLEC1,TP53,B3GNT2,TOP3B,RAF1,FURIN,PDHA1,TFCP2,TFRC,GJA1,PHB1,COX4I1,RAB35,RMND1,TMPO,CDK9,PTP4A3,HDAC6,UBXN6,DPP4,STYK1,TMOD2,SHC1,EID1,HSPA8,PML,SIRT7,FOS,RHOU,RPA3,FTL,SKP1,STAU1,CFTR,TOR1AIP2,ATG16L1,PSMC4,TFIP11,RPA2,UBASH3B,PTEN,DKK3,LURAP1,PELO,DLST,CCNF,ESR2,VIRMA,SMURF1,UBB,SH3BGRL,ACTB,RHOJ,STAT1,TMOD3,CTSB,DAPK1,AR,BTF3,RAB11A,SCN3B,CUL3,MYC,ILK,UBE2H,EPHA2,RHOB |
| 4.365e-05 | -10.04 | TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | REACTOME pathways | R-HSA-975138 | 91 | 47 | 10285 | 3229 |
NFKBIA,TLR7,MAP2K3,SKP1,UBB,PELI3,PPP2R1A,PELI1,UBA52,TLR4,MAP2K1,MEF2C,S100B,DUSP6,FOS,TAB1,CREB1,ELK1,FBXW11,TLR9,JUN,AGER,TLR8,LY96,NFKB1,IRAK4,MYD88,CD14,HMGB1,TRAF6,DUSP3,TICAM2,IKBKB,RPS27A,UBE2N,MAPK10,MAP2K6,TLR3,MAPKAPK3,NFKBIB,ATF1,TAB2,DHX9,MEF2A,UBE2V1,PPP2CB,TICAM1 |
| 4.429e-05 | -10.02 | cellular response to biotic stimulus | biological process | GO:0071216 | 247 | 102 | 18204 | 5365 |
CSF2,IRF3,PDE4B,MIR140,DDIT3,TLR4,CD274,SRC,BCL10,LILRB1,PDCD4,CLEC7A,IL6,CAMP,CD86,MMP9,CXCL9,MIR223,CXCL8,DEFB124,TP53,IL12B,OPRK1,CXCL13,CAPN2,CDC73,MIR21,CXCL3,MIR146A,TSPO,TNFRSF1B,TLR9,CCDC47,HSPA5,GFI1,ZMPSTE24,MYD88,MIR342,CHMP5,IRAK4,CD36,CD80,MEF2C,LDOC1,TLR1,TICAM1,TXNIP,NFKBIL1,TLR6,FCGR2B,PYCARD,CXCL1,MTDH,SELENOS,STAP1,HMGB1,CEBPE,SYK,NFKBIB,PTPN22,AKT1,CD40,IL1B,TNFAIP3,CX3CR1,PLSCR4,GSTP1,CXCL11,LY96,PLSCR3,NFKBIA,NOTCH2,TNF,MAP2K3,IL1A,IL10,PLAA,LITAF,PDCD1LG2,CYRIB,CDK4,XBP1,MIR17,MIR20A,CCR5,TRAF6,NLRP3,CD14,TLR2,TLR10,TICAM2,IRF8,MRC1,HDAC5,PRKCE,NFKB1,CXCL10,CCL2,JAK2,MIR105-1,TIRAP,MIR187 |
| 4.476e-05 | -10.01 | TGS1 (trimethylguanosine synthase 1) | protein interactions | 96764 | 71 | 36 | 19454 | 5460 |
DNAJB4,SEPTIN7,CRY1,EP300,SNRPA,NAE1,COIL,SNRPG,KRAS,FBXW7,IGFBP3,CFTR,SNRPN,SNRPE,LSM10,SNRPD2,EED,MAGED2,FAM177A1,LURAP1,NFKBIB,RSRC1,EGLN3,VIRMA,SNRPB2,NOP58,SNRPA1,SNRPD3,XPO1,SNRPB,CREBBP,SSX2IP,KPNA1,RIT1,FTSJ3,SNRNP70 |
| 4.482e-05 | -10.01 | biological process involved in interaction with host | biological process | GO:0051701 | 152 | 68 | 18204 | 5365 |
ITGB5,ITGAV,CDK1,PPID,CLDN6,EPHA2,SRC,CHMP1B,VAMP8,HTR2A,HSPD1,AKT1,DAG1,LDLR,CXCR4,VPS4B,ITGA2,GPR15,NECTIN2,RNASEK,CD209,RPSA,WWP2,SLC7A1,ICAM1,HYAL2,AVPR1B,CHMP1A,PHB1,TFRC,CLDN9,SLC20A2,LAMP3,CD86,VPS4A,TRIM62,PPIA,F11R,SIVA1,CHMP5,CBL,CCR5,WWP1,IDE,CLDN1,CHMP4C,DPP4,BECN1,CD46,NUP153,CD81,JPT2,PLSCR1,CD4,CAV1,TSG101,PC,TNFRSF14,CHMP2A,CAV2,NRP1,CTSB,CD80,CHMP2B,MRC1,HSP90AB1,VPS18,MOG |
| 4.494e-05 | -10.01 | intracellular organelle | cellular component | GO:0043229 | 13594 | 4062 | 19108 | 5553 |
TOR4A,ELOVL6,DNM2,CLCN6,GTF2E1,CYP2C9,PPTC7,SLPI,PPP1R8,GABRA1,CABCOCO1,ARF6,SERTAD1,ZNF24,UBIAD1,DAPK1,PYROXD2,ASF1A,ACTB,FERD3L,GDI2,MYD88,PLCB2,CDK6,GZMK,PRPF18,SLC16A10,ZNF596,PIR,TMEM30A,MORC2,MRPS23,DAAM1,SLC35F1,PHF12,CLDN11,RGS19,COX16,PSMA4,UQCC2,KPNA1,MAEA,PLA2G4B,CGAS,LDHAL6B,ETFBKMT,DHRS1,SKP1,LSM14A,TRIM34,G3BP2,THAP7,MEPCE,DHRS3,UBE2K,SEMG2,GK5,RACGAP1,NDST1,ETV6,RGS10,STAT1,SERINC3,CRTC2,F10,FSTL1,MRPL51,PFDN2,PRIM2,SRP72,CCNA2,SLC51A,CCSAP,HACD2,WDR82,LYZL6,CDC20,YKT6,PRL,SLC22A17,SPINDOC,GCFC2,SRPRB,RPL23,NR0B1,TIMM13,SLC35E1,HP,RPGRIP1L,SYNDIG1,PITHD1,MTPN,HSPB1,TULP3,BORCS6,UQCC3,POLR1B,SLC6A4,MTERF2,RARRES2,TFE3,RBP5,CCNF,HSCB,TAS2R16,SRD5A3,GSKIP,RTCB,RGCC,SLC25A10,MED22,PACRG,VAPB,HR,FOXP4,EZH2,ATP6V1G2,LBH,DCAF16,IFIH1,AIF1,SDCBP,TREML1,CAND1,ERO1A,MTMR6,HSP90AB1,GTF2H5,FURIN,PRDX4,CARTPT,TES,RAB40AL,MYRF,OARD1,NOA1,TLR2,TMEM14B,DYRK1A,RBM5,PSMD14,WDR44,TRIM35,PRCC,DLST,CD274,CLXN,RAB3B,EVA1A,RPRD1A,B3GNT2,SOX21,CYP2C8,JKAMP,UQCRH,F9,ICA1,TRAM2,MRPL11,GFM1,ALKBH4,FAHD1,ABCF1,CLN8,RPAIN,SCML1,RDH11,SELL,BHLHE40,PPARG,TIMM29,H1-5,CHP1,MED10,CCDC181,IFRD1,UBE2D1,BOK,CLRN1,SLAIN2,FUNDC2,NDUFS6,DNAJC2,GPC1,GAS2,TSEN34,SERTAD2,GCHFR,ZNF790,NSG1,ADH1A,OPRM1,CIART,UBXN6,CD2,DDIT3,NDST3,RC3H2,RNF113A,CD2BP2,SLC35E4,SLC25A32,SLU7,FTL,AGTRAP,CYP2D6,MRPL53,ALG11,CAPN2,LAMTOR3,ATXN1L,NR2F6,DSTN,RAB14,RBM7,HDAC11,FYTTD1,PSMG2,ZNF436,EFNB1,DCTN3,CYB5R4,BET1L,CSNK1A1L,HNMT,ZBTB45,RERE,NEUROD2,PAX9,GTF2A1,SFTPA1,TP53INP2,MYL12A,DNAJC7,GOSR2,OPHN1,TUBG1,HCFC2,FABP12,SARM1,MEF2A,RMI1,SGIP1,CCDC65,GLRX5,NDUFS2,RBM22,GALC,NUP153,TAX1BP1,HAUS2,MGME1,CDAN1,HOXB1,CSH1,TIMM23,EMG1,PRDM4,HRAS,TPPP3,FUNDC1,SLC25A44,PDHB,KLK3,RPS5,SYCE3,IL12A,TIMP3,NUDT9,TTL,RPS17,PEG10,LAMTOR1,NUS1,PSKH1,ZNF652,APH1A,WDR37,CCR5,GNB1,TEX19,ADK,ARF1,PDSS2,MT1A,NQO1,THG1L,ACSL4,SCAMP5,FUT1,LGI3,UHMK1,ACACA,CDK9,NAB2,GPC4,TRIM46,MAF1,AGK,IFT25,CHMP2A,VGLL2,CHST2,MCOLN1,SUMO1,AVPR1B,POMT2,YPEL5,STX1A,SERPINB10,HTRA2,RAB9A,RPS6KA4,HNRNPL,PGRMC1,DYNC1I2,TVP23B,SFT2D2,STAP1,BUD23,TMEM123,CNOT2,URAD,MYCT1,DNTTIP1,RABAC1,CDC42SE2,CISD1,CD1D,LYZ,DBT,PPIC,TRIB1,PRPF31,RTKN,COP1,POR,CRISP1,TBC1D5,OCRL,WNT7A,CAPG,STARD4,H2AC6,PMM2,SF3B4,UGP2,PRDX1,CYTH1,SETD3,METTL6,CBL,APOBEC3A,C1D,KXD1,LYZL4,PDE7A,CREB3,SLC4A8,RCHY1,DNAL4,LDB1,TRA2B,BCCIP,BANF1,CCR7,CNOT6,INPP5E,CYBC1,UGT1A1,MYL12B,CNOT7,TRIM3,KMT5B,BFAR,SELENOF,GTDC1,SPRED2,PTRH2,FXN,DPEP3,TWIST2,MRPS26,TFB1M,ARG2,HFE,SNRPE,UBE2E2,EHBP1,CEP85,SAMM50,FBXO22,GABBR1,WDR83,JPH4,AMACR,EI24,CX3CR1,NKIRAS1,B2M,PIGC,ZBTB16,LTBR,ACHE,RLIM,SPTAN1,ISG15,CHMP1B,KGD4,SIAH2,RUVBL2,CCR2,MREG,EIF5A2,NEU1,RPP25L,FLCN,ATP5PF,PROX1,SYVN1,CST11,MBL2,VAC14,ZDHHC8,G6PC3,MXD1,RAB1A,CYP4F8,YTHDF2,ANKRD50,GFM2,PSENEN,HSPA14,AP3S2,CTTNBP2,EYA3,CDKN2AIP,MYO6,PGM1,AGER,FAM53B,RHCG,TEDC2,FOXN2,QRSL1,RFC4,MSX2,CTNNBL1,ID4,UGCG,CLBA1,HSP90AA1,SYT2,TBCCD1,TRNP1,AFTPH,GTF2H2,TIRAP,RAD23B,CFAP91,ZNF263,CRYGB,IKZF5,NEUROD6,ACADSB,MARCHF3,RERG,ALB,HDAC5,COL1A2,NDUFB5,DNAJB4,GTF3C4,TIMM10,AUH,EMX2,EID2,OVGP1,GNB4,TSNAX,SPMIP8,UBB,RNF152,EMP2,IL15RA,MLF1,CHAMP1,CWC15,TPPP2,ANAPC11,AGR2,PTPN11,CCN3,G0S2,MIOS,SMAD1,PYM1,RNASE6,TUSC3,RMND1,ADRB1,DPY30,SYBU,PAPOLA,GABRB3,ERRFI1,BTG3,BTG1,OLFM3,LCORL,CSTPP1,TM9SF1,MYH2,PPP1R11,CIMIP2C,CDK17,PPP1R12A,ZNF473,PTEN,SLC16A1,ZNF787,GLT8D1,PHB2,HNRNPAB,MAPK10,AMT,KATNAL1,AATF,AIF1L,IRF3,SAP30BP,VAMP7,GTF3C3,RPL3,ARMC7,POLR2B,PHF23,TMA16,MTG2,H2BC17,FTSJ3,NFKBIL1,CBR3,HEBP2,CRBN,SP2,PEBP1,OSR2,CYB561D2,SPCS3,PMPCA,TMEM39A,LRIF1,CCDC186,PSMB4,MGARP,IRAK4,BACE1,POLD4,TNKS2,NCKAP1,CHPF2,SMAD9,TOR3A,RAP1B,FERMT2,B4GALT4,GRIK1,STARD13,USP6NL,RFLNA,RFX5,THOC6,HEXIM1,FOS,ABCE1,RDH10,TOPBP1,LST1,NRM,MOXD1,TCP1,LRRC8D,MDC1,ELOVL3,PHF13,NEDD8,PABPC1,REEP6,CAB39,CHTOP,FBXW11,SERINC1,RUVBL1,ZNF451,COMT,SYNGR3,FUT8,GABARAPL1,C2CD2,MTRF1,OLA1,TIGD7,CDKN2D,PGAP4,CDKL2,RBM3,PDF,RAB32,MRPL33,S100A6,FGF13,PSMD1,CACNG3,ATP5F1A,MGAT5B,HSH2D,EMC1,REEP4,POLR3B,SNRPA1,UBE3A,RAB11B,THBD,TNRC6C,DRG1,RSAD2,SEC11A,CDC23,PIGW,TMT1A,RADX,ACSS2,DERL2,MRPS18C,METTL15,LDHB,TRIM22,RAB6A,RPS26,TMEM190,SMUG1,QPCTL,SUCLG2,HSD17B6,FAM222B,BOLA3,NDUFAF4,PLSCR3,COX7B,SKAP2,PICK1,HOXD12,KIN,FOXP1,CCNB1,SRP14,RPN1,TGFB3,CHST10,MTHFD2L,TRAF6,DXO,EIF1AD,IK,DTL,GAPDH,FGL2,USP39,DERL1,MND1,GDPD3,ADRM1,CINP,CREB1,IRF2BP1,TAF5L,B3GALT2,RRP7A,IDE,TAPT1,LGALS8,SEC22C,CRLF3,PCYT1B,RPL27,PTGDS,IER3,FGF1,GADD45G,FAM193B,SRSF8,THAP1,MRPS18B,RIOK2,TMEM160,COX20,SGTA,CNPPD1,SNX24,FMC1,LSM4,H2AC7,VPS26A,SEC61A1,DHX38,MYBL2,UTP23,PPP1R26,NKX6-2,RPSA,SLC31A1,APOBEC3H,EGLN3,JAML,RCCD1,STIM1,JADE1,LIPA,ATP5F1E,RBM42,CCAR2,TMEM168,SUPT7L,MIF,SPTSSB,NAA15,FAF2,SRARP,HNF1B,CDC7,PPP1CC,JUNB,NDUFA2,MTM1,RPL37A,ZKSCAN1,PKIB,SSH3,TIMM17A,ELOF1,SSBP4,IKZF2,STK38,MPHOSPH6,HYAL2,NEK7,TRIM23,VPS26B,DYRK1B,RUSC2,UBE2L3,SIPA1L1,SCNM1,TERC,TAGLN3,HIRA,PSMC3,AMELX,ASCC1,PGAM1,MPDU1,SIGLEC5,GJB1,MORC4,CASP4,H2AC13,VPS26C,UBASH3B,H3C1,ISCU,TMEM45B,WDR6,ASRGL1,STAU1,RGS6,KLHL15,HMGA1,RPL23A,CTSC,SLA2,SUMO2,SSR3,DHRS7,TP53,TOM1,SPC24,SNAPC2,ZNF32,GPX4,MT2A,TNNC2,APEX2,AP2M1,MOSPD1,RETREG2,CCDC85B,SYNJ2BP,ESD,PCCB,PATE4,POLR2F,IFT172,PPFIA2,CSRNP1,E2F4,SNAPIN,CDC37L1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22,FNTB,CCND1,POLR2I,TPPP,CBX5,RAN,TAMM41,HCLS1,KLF9,POLR2D,FKTN,ZNF250,ENY2,BCL7B,ZNF365,FXR2,AP2S1,CWF19L1,SYK,SFTPD,TMT1B,SUPT5H,BAX,PCK2,TACO1,TESK1,HNRNPA0,ZC3H15,TXNL4A,ETFA,HSPB8,MCM3,LYNX1,LMNB1,UBE2V2,SNRPA,FAM161A,ELK4,USP5,SWAP70,ATP6V1D,TMEM14A,HMOX2,PRPF19,ACP6,SLC39A7,PIWIL2,BAP1,MED17,BEX3,CHID1,MAP2K3,CFAP161,STX16,NTAQ1,HIGD2A,ELOC,MEIOB,OLR1,H2BC11,LDLRAD4,FNDC8,TNPO2,RNF128,SEPTIN7,SPMIP10,CXCL14,MYO1B,VIPAS39,DUOXA2,RANBP10,CH25H,SERTAD3,ING2,TMCC2,POLE4,CDC26,PGA4,NECAP2,TLR8,CCAR1,RPL32,FKBP1A,ZNF770,AKAP8L,SELENOP,GON7,PTPN4,VXN,BOLA1,TPBG,CTTNBP2NL,RPS11,CCIN,TBC1D17,ASB11,BRD9,TRAPPC1,KCNG3,IDH1,B3GALNT1,PPME1,RPS2,MAP2K1,SHOC2,LILRA3,HNRNPD,SERPIND1,RAB8B,PLEKHF1,UBXN2B,TOP1,ZMYM2,TBC1D24,RETSAT,ZNF622,RPL4,ZC3H7A,STRBP,VTA1,EIF2B5,GCC1,TRAFD1,METTL14,KBTBD6,CTSD,CTNNA1,TMED3,RNF167,ISG20,IFNAR1,SPOP,ZSWIM7,ZMYM6,NECAP1,USP15,TRAPPC13,PSMB6,PPP3R2,RIGI,MLF2,DPP4,FADS2,TMEM59L,CTSA,LDOC1,EMC8,TGFB1I1,PHF1,ZDHHC14,DIPK1A,MTMR2,ARHGAP21,TAF10,CCT8,ETFB,RPS27A,LYSET,ABHD17A,FAM53C,FAR2,NFYA,LSM5,OST4,ATF1,PGR,STOX2,MAPRE2,TAB2,TMEM106B,VKORC1L1,CLPX,ANKRD6,ZNF821,ARPC3,PWP2,ERLEC1,RBFOX3,ARPC2,ATP5MG,PAFAH1B1,NCAPG2,PNP,ASPM,SFN,BEND6,SETD5,MAPRE1,HADH,BIRC2,ASTN1,TNFAIP6,CRYBA1,WSCD1,TWNK,ZNF177,CEND1,CSRP1,GCA,RXRG,FAM91A1,KARS1,TMUB1,ILVBL,PML,RTF2,TOP3B,USP14,PSEN2,FLRT3,TBC1D25,HAS3,CBX3,STBD1,SPON1,NUDCD3,ZNF687,DNAJC25,CYP4F12,GSTP1,ZSCAN25,GPAM,EIF4E2,MRPL57,SPRN,COX6B2,KRR1,FRMD8,ZNF22,CLVS1,TIMM8B,CYTH2,BCL10,HOXB8,FAM210A,PRNP,GTF2F1,CEBPG,EXOSC3,RNF115,TUBB,TLDC2,RGMB,RAB11A,EEF1A1,NPC2,KLF10,NFE2L2,ZFP64,RETREG3,TMEM179B,TRIM36,IGF1,NEFL,HYPK,CPSF2,TRMT61A,RPS4X,PSMD4,NPY,MAD2L2,UFM1,RAB28,EMC6,STT3A,IPO8,GIMAP2,PSMA2,DUSP26,NONO,PRDX3,RPL39,STAR,STK26,INO80C,NXT1,GABRG2,RFC2,MYORG,EDF1,CUL2,RILPL2,CIDEB,FAM8A1,TBCEL,CBR4,POLR1H,ARHGAP15,FHIT,MAVS,BNIP3L,PPM1M,MZB1,TRA2A,MEF2C,TMEM100,PYCARD,GAS8,CDNF,ZCCHC12,NUFIP2,FBXO3,DBH,MRPL34,STARD7,PAFAH1B2,GLIPR1,CYP17A1,NDUFC2,RAPGEF5,TRMT1L,FMOD,PDIA3,PQBP1,PXMP2,EIF2AK2,ZCCHC7,CNTROB,SRFBP1,NDUFB7,SEC61G,G3BP1,ILF2,EIF3G,ARHGAP5,SRSF7,AZIN1,KLK5,HBA1,PSME2,TRAF7,ITGB5,MAEL,CSRNP3,TFRC,CHMP4C,ZC3H11A,SNX10,COA4,ST8SIA4,MED11,GPBP1L1,YPEL4,ST3GAL5,ELOVL7,PPARA,LINC02914,BAG3,AIPL1,TIMM21,PSMB1,OVOL1,NAA30,ATP6V1C1,TMEM126B,LBR,MBD3,COQ10B,NAA35,PTN,ARMC1,GAPT,NEK2,UQCRC2,TAPBP,GALNT1,TMEM33,F7,CALY,MRPL36,CYP11B1,SCG3,DLX1,GCNT3,AQP4,ATOSB,CACNB4,TUSC2,HEXB,BST2,RETREG1,FLRT2,TRIM27,MRPL47,ALG2,PKIA,TNFAIP8,NGB,SESTD1,RAB5A,SLC66A2,NLRP3,CYBRD1,LRP6,DET1,NGRN,CREG2,CCT2,KLHL1,MYH1,SLC1A3,SMAD2,ZNF343,RNF139,KANSL3,NOVA1,FBP2,PPWD1,CENPM,DUSP21,TMEM106C,NR4A2,PDP2,CTDSPL2,LRRC8A,RRM1,LCP1,RPS20,PTPN5,DNPH1,RPL15,GEMIN8,SELENOS,OSBPL8,TRIM8,SGMS1,PAQR3,MYOZ3,COPS7A,NUDT12,PMP2,DPM2,HLF,KLHL7,RAC2,MED13L,VPS39,DBR1,EGR1,RGN,ARHGAP1,CTDSP2,LIMD2,VPS4A,ISX,CPSF4,PDE9A,LSM2,LAMP3,FCGR1A,GDE1,RPL9,SRPK2,TRIP4,DENND2D,FAM241A,LDB2,FCMR,CCNH,NCBP2,UST,RNF187,DUSP10,ANP32A,PROM1,NDUFAF3,HAX1,ARMCX3,PPP2R1A,ZNF692,NR1I3,DDAH2,CIBAR1,DNAJC30,NDUFS3,KRIT1,HIGD1C,TMEM174,CTBP1,SKA2,OTULINL,DDIT4,HELLS,KLF4,CDK5R1,PRMT5,CMC1,TAF7,DTWD2,GNPTG,RHOB,RSBN1L,DDRGK1,PDHA1,TPT1,CRHR1,ANKRD49,F2,PAK2,PHC1,ZBTB38,ADCK1,UBE2I,ROCK1,RHBG,NUDT1,EIF2S1,TMED7,PIP5K1A,TRUB1,MAP1LC3A,DHX9,SURF4,UBAP1,CHI3L1,MMADHC,SNX12,MCCD1,ACTL9,DMPK,MRPS11,PRCP,ISOC1,KLHL3,TLR1,SAP30,VAMP3,SMARCE1,CGRRF1,SPTSSA,FBP1,EXOC8,CASP12,CLDN8,TXNL1,DRG2,LSM8,PIK3R2,RPL17,S100A11,SAR1B,HSDL2,CDCA7L,LEPROTL1,AKR1B1,MNAT1,PSMD10,CHST7,CTSK,SV2B,EIF4A3,TRIM52,SIRT7,CXXC5,HAPSTR1,CREB3L4,SLC25A51,KDELR2,RNASEH2C,RAB3C,RELL1,RWDD3,STAT5A,RAP2A,DYNLT3,RPLP1,NAA50,FAM241B,EGR2,RFXANK,IFI35,RNF126,JAGN1,CSGALNACT1,CPT1B,ISCA2,ADSS2,ZBTB18,UBE2D3,STOM,SNRPD2,SAV1,SPMIP6,FAM76B,YIF1A,PITPNA,PYURF,HENMT1,TMEM177,CFAP61,PSPC1,SMCP,MED23,APOC2,MTX2,SLC25A39,CAV3,REEP3,RNF14,VPS33A,PPIG,IMP4,SPMIP5,MARVELD1,ZNF319,GPNMB,INPP4A,FOXC2,ADIG,RHEB,NICN1,MED29,CKB,IMMP2L,CACYBP,FAAP100,TNFSF13,UBE2H,TMBIM1,DNAJC10,SNRPN,MRPL40,PLEKHO1,MAGEC2,MSH6,CMKLR2,NUDT4,EMC2,MAP1LC3B,PFDN5,PABPC5,TAF2,GLRA2,SNAI2,TTC1,MOB4,SERPINB9,TP53TG5,MUL1,RP2,UBE2E3,CHIC2,TRAPPC2L,WEE2,ZNF664,YAF2,SIAH1,POU3F4,ZMAT5,GTF2E2,CDK5RAP3,STK38L,RAB1B,UFD1,JAKMIP2,VPS18,NR2E1,TIA1,TMEM198,SLC38A7,RPL7L1,EHHADH,PHTF2,RBM34,TEX12,CDK5,NDUFB10,MAGOH,GRSF1,RAB3A,FEN1,AK3,TPM3,MAB21L1,RBBP4,DICER1,ATG16L1,TOMM40,DUSP3,GID8,HEXA,TLCD3B,MSX1,IL12B,RNF133,UGDH,GNPAT,UBXN10,MAP3K11,CCS,SPATS2L,ZYX,DCTN6,ATG7,MANSC1,SLC35A1,SPEF1,RABL2B,MSRB1,ZNF575,TIMMDC1,SPR,ENPP4,BRINP3,HCFC1R1,RAP2C,POU1F1,TDRP,TM9SF4,ASPA,MECP2,GRAP2,RPL7A,TMEM115,H2AB1,DR1,CTTN,TRAM1L1,PREB,SNIP1,RCBTB1,SEPHS1,DCTPP1,NDUFB8,SMCHD1,MTCH2,AP5M1,CD59,SERTM1,DYNLL1,ARFGAP3,TASL,CFAP298,UBA52,SDHAF1,VPS54,SLC39A9,CHST13,FAM81A,PTP4A3,ZNF362,TSPO,CFDP1,ERG28,EIF3K,RAB9B,DDX5,NUF2,CD40,NMRAL1,EHD4,ARL5B,CIB2,CEP19,YIPF4,MARS1,SDC4,GLRX,SLC48A1,BAG2,EHD3,EZH1,KDELR1,DHX16,NDUFAF6,CYP21A2,SNX5,NUPR1,RPS16,CCDC92,H2BC12,CATIP,ZBTB25,OAZ1,NOSIP,RAD1,PROS1,SUGP1,RAB33A,CSNK1E,NT5C3A,PIGA,SLC52A3,PSMA3,DDX39A,CCDC69,HEXIM2,CYRIB,NUP107,POLR3F,HSPB2,ATP5PD,ARFIP1,NHERF1,AIFM1,NPPC,NAE1,MIDEAS,COA1,CGGBP1,PRSS37,BCL2A1,GABRA2,FANCG,LRAT,CYB5R3,RNF121,EPHA4,UBE2B,ARMC8,SLC35E3,PRKAB1,NCDN,GNPDA2,BAALC,RAB18,TRIM29,CSKMT,BLOC1S3,FCHO2,CYP1B1,BORCS8,CEBPE,TOMM7,IFIT2,TOR1AIP2,ZNF655,CLEC18A,LSM6,PRKCQ,GH1,CCNY,SF3A1,NOL7,PSMA5,PTPN22,STX7,ABHD6,CSNK1G3,GABARAPL2,PSEN1,TAFA1,S100B,VRTN,SSX2IP,MACROH2A2,SOST,AKT3,GADD45B,CDC5L,CD164,SETD9,LHX2,RNF34,CYSTM1,B4GALT1,IRAK1BP1,AKAP12,KIF2A,SLC25A17,WDR55,CDC42EP4,LCA5,KICS2,DNAJC19,S100PBP,TXNRD3,TSPO2,SLC30A7,CKS1B,IGF2BP1,RBM12,INSIG2,MRM2,TLR3,RFC5,RCL1,DUSP9,TRAK2,HDAC3,PAAF1,ENPEP,TBC1D10C,METTL22,MAN1A2,PFDN4,UBA3,TMEM165,STAT2,LDHA,EXOSC8,MDFI,LCMT1,NDC80,NSA2,DTYMK,ABHD14B,GPHN,SSPN,STX17,SLC1A1,MAD2L1,TICAM1,XBP1,CYTH4,KRTAP12-4,SDF2L1,PRR13,TCAP,PSMD7,FOXA3,PSMD12,TMEM126A,DCUN1D5,HM13,TEF,LRWD1,LIMS2,OTX2,NPTX1,TLR9,INTS12,ACOT8,STN1,NFIL3,STAT6,HNRNPK,SEC61A2,TMEM117,NTRK2,DYNC1I1,PFKFB2,ATP5IF1,ATP2B4,GRM1,CDIP1,FIS1,CRKL,TGIF2LX,DAPK3,STOML2,ENO1,MRPL24,TMEM50A,TMEM170A,SNRPD3,MRPL10,TMIGD1,CAMKV,PRM1,USP46,MIS12,TRIM45,EXOSC4,SRGN,DNAL1,PPID,AK5,ALYREF,ORC6,TFPI,CDK2AP2,ACOT13,OPRL1,OCIAD2,HP1BP3,CRTAP,RPS24,ANP32B,TMX2,GATD3,ENKD1,TNFRSF1B,NAA60,RRAGB,EDC3,MTA2,HECTD1,SUV39H1,CD47,RARS1,TOM1L1,PDE8A,SCYL2,PHETA2,STRADB,POLB,TNFAIP8L3,HADHA,COPS7B,KDM1A,NKX3-2,CDC42EP3,APOBEC3D,DRGX,AP2A1,SCAND1,ERLIN1,ANAPC4,FASLG,ANAPC2,FCAR,PDE4B,STPG4,GTF2A2,NAP1L5,CHRAC1,STMN2,FAM20C,MEST,POLE3,CRYM,PNMA3,LPCAT3,RPL12,IFT22,CD4,DNAJB9,PPP1R10,PELO,GABPA,CDK8,GPRASP3,CRHBP,NAB1,RMDN3,SLC38A9,AKT1,PPFIA3,TRAPPC14,SLC37A4,SIVA1,DCAF5,ACTR1A,STK24,TLR4,TNIK,TRIM54,CXCR1,COPS2,PLEKHA8,CD1C,DLG4,SPRY1,BRCA1,ZCRB1,SNN,MGAT4B,GSTM2,CYP2R1,ZCCHC17,GLUL,ARF4,CD14,PIWIL4,ADD2,NUDT2,RBP2,ATAD1,PCGF6,NIBAN2,DROSHA,CHCHD4,NUDT16,GLRA1,H1-3,FIG4,CHMP1A,ZNF862,CAMLG,TMBIM6,SNAP29,LANCL2,CHGA,KCNA2,GADD45A,CREBZF,PPP2CB,TOLLIP,RPS23,RPL10,TNNT2,SRPRA,CFAP119,FIBIN,BRIX1,SLC25A1,COA5,TOMM20,AGO1,MEAF6,RORB,MPHOSPH10,NBN,HOXC4,ZFAND2B,P3H1,EFHC1,S100A10,DKK1,CDKN1A,NDUFB4,STX6,PLPPR1,SPACDR,PDE6D,GTF2B,PRKX,PPP2R5A,PAK6,H2AC4,CD86,SMARCA5,GRAP,IL15,TEX261,YWHAZ,TNPO3,RAP2B,CAMK2N2,PARL,DEGS1,FHL3,PNMA2,AKIP1,SURF6,TRIM68,TAGLN2,JAK1,RBIS,IRF2,MRPL16,HERC4,H2AC25,MCM6,CFAP20,GNAI2,PCLAF,CNR1,FITM1,NOC4L,PLCB1,ELK1,TMSB10,FABP5,B4GALT6,LRRC8B,DDX4,OR51E2,EMC4,TFIP11,CTNND1,TOR1B,CRY1,COX4I1,DESI1,RPL26,LEMD3,RAB37,HOMER1,SSRP1,VPS16,ZBTB42,B4GALT7,SEC14L1,ABHD2,LMBRD1,COMMD8,IRF8,CRAT,SPECC1L,ABHD10,OTUD7B,ADAMTS1,ELOVL4,HSD17B10,ARFGAP1,RPL10L,PDCD10,GAD2,TRIM32,CETN3,C1GALT1C1,RAB29,SUMO3,GPX2,JUN,ZNF287,AK2,UNC50,PSRC1,ESR2,COPS5,ST3GAL4,MCM8,TLR7,LAMTOR2,IGFBP4,APTX,SYS1,CYP39A1,APOBEC3G,MSMO1,SRSF2,TMEM89,GASK1B,UTP15,SERPINB6,ZNHIT6,HSD17B11,SLC7A14,LUC7L3,MRC1,WTAP,SNX2,SRI,GORASP2,TMEM70,THRAP3,CELF6,SNX22,PAK1IP1,GABARAP,CHCHD6,RAB6B,EIF4EBP2,CFAP73,BRMS1L,PLA2G5,SLC41A3,PNPLA8,BPIFA2,LGALS3,TMEM97,NDUFA1,CPE,EPOP,MINAR2,RPS13,RB1CC1,KDSR,R3HDM4,AKAP17A,LAP3,MAIP1,CHRM3,EIF5B,STX5,OSGEPL1,HSDL1,STX10,SLC8A1,DTD1,IPP,MIR17,NLE1,SOD2,DMAP1,LY96,LSM10,GLRX2,TSPAN5,CFAP36,SNX17,LRRTM1,BUB3,ZNF704,RAB3D,TLNRD1,TICAM2,ADNP,ZNF576,IFT57,COX19,RNF40,CLK4,HS3ST5,MINDY3,DPH3,SVOP,ACTR2,PACSIN3,MRPS25,TP53INP1,MRPS28,MX1,TCEA2,FZD4,SLC25A11,HDAC6,DPEP1,NEUROG2,MTG1,MED21,FAM107A,MZT2B,GPR85,GINS3,CPSF1,CAV2,GOLGA5,IKBKB,TRMT112,FA2H,ZNF518B,MTA3,UQCC6,OCEL1,NAA16,LIAS,BSCL2,MPST,SNAPC1,TOMM40L,VDR,RPL19,AQP2,ANXA4,VAMP2,NAIF1,ATP5MC1,SNRNP48,SPCS1,SLC12A2,MCRIP2,PRSS12,CHST9,TCP11L1,ZNF501,ORC5,CBLL1,TMOD1,LAMP2,EEF1E1,VGLL4,ATXN10,NDUFAB1,LBX1,GEMIN7,ZNF345,HDHD5,TRAM1,PRDX6,PRRC2A,STX18,PPP1CB,CCT7,UPRT,WDR83OS,PRMT2,PARP2,CYC1,MAP3K14,ZBED4,PRKAG1,LYPLA2,VAMP5,TOPORS,QTRT2,COX5A,PC,DEFB1,FKBP4,TPGS2,UBAC2,NOS1AP,GHR,NCSTN,ENTPD4,SOD3,SH3BP4,EXOC3,SLC15A2,B4GAT1,HMCES,ACO2,PLP2,BAHD1,NAP1L3,MAGOHB,EHD1,CARD19,XXYLT1,TRMT10B,ZNF330,RNF208,COMMD9,RDM1,H2BC1,KRT7,ALG5,FBXO32,RFX4,B4GALT3,BRMS1,RPL6,RPS28,BGLAP,ZFAND2A,USP16,B9D2,SLC13A5,GAMT,DPAGT1,MAP2K6,HNRNPH2,GOLGA7,SOX9,PLEKHO2,PRKRA,H2BC14,ZMYM3,COX8A,MRPL9,PSMB5,CAVIN2,GOLPH3L,VMAC,TMEM176B,SKA1,ARPP19,FGFR1,RPLP2,STC1,SYNPR,SNRNP27,BMP1,TMEM91,MYL6,RANBP1,DRAM1,TTR,CSTF3,EIF2S2,PSMB9,SYNGR4,MRPL41,MDH1,GLT8D2,NFKB1,TGIF2,TAL2,HNRNPC,CLIC2,GLIPR2,FTSJ1,ARL2BP,MAPK4,NLRP2,WDR3,HPF1,WDR5B,TOMM22,CAPZA2,SLC2A8,HMX1,SH3BGRL,PELP1,B3GALT1,FAF1,INA,NF2,SPRYD4,IL6,DYNLRB2,SLC30A5,PRR19,PIP4P1,MRPS35,ELF1,NR1H2,SDHAF4,ATF4,CSE1L,BABAM1,MKLN1,PRICKLE2,CD1B,SERPINH1,CALR,PPAN,RASL11A,SLC25A42,SLC25A27,SPRED1,NOP53,UBE2M,CAMSAP2,DIO3,OGDHL,CAMP,TSR2,EMC9,SELENOI,SPATA2,PPIA,DIPK2A,MMAA,SNRPB2,MRPL20,BUD31,METTL18,TAB1,S100A8,RIT2,CYB5R1,NLRP6,CD247,CDKN3,APEX1,PSMD3,FGF7,POMP,SNX18,CNIH4,AP1M1,TOM1L2,KCNJ8,CEP41,MCAT,FAM20B,MLLT11,SDHAF2,NLRP1,MGAT1,CAPZA1,BACH1,MAFG,RIOX2,RANGRF,TNFAIP8L2,FTH1,SP1,FKBP10,BICD2,IRF6,CBLN3,TYROBP,DECR2,AZIN2,GAL3ST1,CHDH,BCS1L,WWP1,HBB,OAS1,SLC25A31,HNRNPH3,TMEM203,PEX3,PAXX,RGS2,GNL1,MRPL23,SST,RBM15B,PITPNB,RPL7,CFAP95,SRP54,TNF,B9D1,CYP27B1,RAG1,TRAPPC4,PIGY,VDAC1,TMEM50B,CYB5B,GALNT17,YWHAB,ERH,TAF11,TGFB2,IRF2BPL,RNASET2,ATP1A3,PSMB10,NGDN,INSM2,RUNX1,EEIG1,SCG5,DNAJB2,IDH3B,FGF23,RNASEL,ZDHHC17,ST6GAL1,GKAP1,DENND6B,FAM50B,SNCG,TMEM127,ST6GALNAC3,TXN,TMEM208,SLC2A3,ATP6V0E1,BBS5,TNFAIP1,MAPKAPK3,MOB3B,ABCG2,TRIM26,ATP5PO,ZNF581,TMED1,HACD3,PTGES3,NCK1,TUBB4B,HPGDS,POLR2G,GALNT4,CD34,LITAF,ZBED3,SERPINB1,OIP5,MRPL52,S1PR4,ROMO1,TLR6,RAF1,DAD1,ING1,SPATA4,PPP1R18,MX2,TF,FBXO25,HSD11B1,GJB2,PLPP6,NME2,FGF12,SPOPL,NACC2,VPS4B,LPAR1,PPIB,PPIF,CORO1C,TMED5,CDC40,COX4I2,SNRPB,INTS6L,JMJD8 |
| 4.510e-05 | -10.01 | Proteasome, 20S core particle | KEGG pathways | M00340 | 15 | 13 | 7161 | 2463 |
PSMA4,PSMA2,PSMA1,PSMB7,PSMA5,PSMB4,PSMB5,PSMB3,PSMB6,PSMB1,PSMB2,PSMA3,PSMA6 |
| 4.510e-05 | -10.01 | Proteasome, 20S core particle | KEGG pathways | hsa_M00340 | 15 | 13 | 7161 | 2463 |
PSMA4,PSMA2,PSMA1,PSMA5,PSMB7,PSMB5,PSMB4,PSMB3,PSMB6,PSMB1,PSMB2,PSMA3,PSMA6 |
| 4.555e-05 | -10.00 | MRPL52 (mitochondrial ribosomal protein L52) | protein interactions | 122704 | 156 | 67 | 19454 | 5460 |
MTRES1,ZNF574,RPL26L1,MRPS18A,MRPL12,RBMS2,MRPL10,PABPC5,MRPL20,MRPL40,RPL4,MRPL57,MRPL41,TMEM177,MRPL17,GFM1,MRPL34,EXD2,NGRN,H1-1,RC3H2,TUFM,MRPL16,PMPCA,RPL7A,MYC,MTG2,RPL19,RPL10,RPL35,RPL13A,MRPL23,RPS9,MRPL13,MTG1,MRPL53,CREB1,TACO1,MRPL51,MRPL49,GFM2,MRPL11,MRPL47,RPL17,MRPL22,ERLEC1,SRSF7,RPL23A,RPL3,HINT2,BCKDK,RBM3,MRPS26,RPS2,TMEM70,RHOG,MRPL18,HNRNPA1,MRPL9,GRSF1,MRPL24,MALSU1,MRPL50,GATD3,PRR3,ALYREF,SSBP1 |
| 4.556e-05 | -10.00 | biological regulation | biological process | GO:0065007 | 12501 | 3796 | 18204 | 5365 |
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4,OR52W1,NLGN2,CCDC25,HP1BP3,MIR222,MIR1180,THBD,CFL2,CAMLG,UBB,COPS7A,USP2,MIR1-2,SERPINA1,MIR185,POLR3B,UBE2E2,CXCL9,GPR26,PEA15,FLOT1,OR10G3,GPR37L1,MT1X,WSB1,IMPA2,SULT1B1,CPLX3,TAS2R13,VDAC1,KCNA2,LRRC69,OVGP1,MORC2,PPP1R17,VPS33A,RMND1,OR51S1,H3C1,POU5F1,SNAPIN,MIR593,BCL2A1,EIF4E3,AQP2,VAV2,ELK1,LYAR,MIR30B,INHA,MIR519D,VWF,MSX2,EXOC1,OLFM3,MFN1,ABCC2,RGS10,MIR548C,RTN4,POGK,ZNF280B,ILDR1,CCL24,CCNI,TMEM106A,GPX1,CRTAP,NPR2,SLC1A2,CTSK,PIK3R3,WDR77,BOK,OR4D6,DDI1,KHDC1,MT1E,MIR9-3,LZTFL1,SDHAF2,ISG20,PRMT5,GABARAP,H2AC6,TBC1D4,MIOS,STARD13,LMNA,DPH3,UBE2V2,G0S2,GRID1,SSX2IP,AKR1A1,RAMP3,OR1F1,GSK3A,PPP1R8,BST2,PKIB,NCALD,BCL2L1,ATP8A1,STXBP1,P2RY10,MAF1,DIRAS2,MSN,CRKL,CTDSP1,PHF21A,ARRDC3,OR10P1,SKP1,PLAA,MLLT11,GPR160,MIR643,OR4D5,H2AC4,AATF,ODAM,FHIT,SLC39A7,PNOC,ZNF451,MITF,MIR216A,CLEC7A,IL21,IDO1,CD1E,TENT5D,PFDN1,TMEM183A,BLOC1S2,CDK6,DNAAF10,FOXI3,AZGP1,DHRS3,SLC4A10,TRIM27,SELENOP,CCL11,C1QL1,PTPN11,SGIP1,ACSS2,ICA1,ATXN1L,PTPRQ,ITK,AK3,EZH1,OSBPL8,FZD6,ESR2,FBXO22,GAPDH,MIR934,PLPPR1,TGFB1I1,AGAP1,CNOT7,POLR2L,LSM6,TPBG,CCNA2,FUNDC2,MIR626,PTGER4,SFRP4,RPL23,CYP7A1,LIPA,SP1,RACGAP1,LIN7C,RELL2,STX12,RHOJ,RNF20,BTG2,PDE9A,STK24,CNTNAP1,MS4A7,SNX14,YAF2,MIR567,ROCK2,ADIPOQ,FGF17,MLN,STXBP6,ZNF304,MIR23A,BATF,OR10A6,MAPK10,S100A10,PREB,ZNF770,INO80C,MIR495,RASSF8,YTHDF1,CXXC5,MME,OR2A25,LGI1,MIR424,ANKH,TRIM23,NKIRAS2,JPH4,BORCS8,ZNF622,ICOS,PSMD10,TNFRSF14,ATAD1,PSMD14,HSPB8,MIR581,ACOT8,CGGBP1,RASGEF1C,GAS2,XAF1,PSME1,CFTR,MTRES1,TFDP2,DDR1,MIR556,GPR17,SLC20A2,PRDX3,PTGES,ZFAND6,APOBEC3G,ANAPC4,CREB1,FRMD8,PRICKLE2,WWP2,MIR216B,HNRNPA1,DNAJC19,FMO2,SPON1,G3BP1,ZNF207,DNAJC30,H2AC13,FGF12,AKIP1,KDM4B,MAGED2,SOCS4,SMAD5,TGIF2,GATAD1,APLN,MOV10,SAP30BP,MARCHF5,KLF9,CD83,MIR190B,KCTD17,MEF2C,CNTROB,LYPLAL1,MSTN,ERLIN1,CBFB,TAX1BP1,ARPC2,GPBAR1,PRCC,RC3H2,SLC20A1,INSYN2A,PLPP6,ZBTB42,TRIM26,AP2A1,PPP1R2,ARB2A,SNX3,MIR421,IFT57,ARHGAP19,MIR208A,IFIH1,ZMYM2,RUNX1,ZMPSTE24,SLPI,CRB3,SPRED2,MXD1,GKAP1,MIR612,RING1,SEC22B,CRYBA1,METAP1,SRPK2,CRIP1,PLSCR3,DBNDD1,SMC4,HNRNPH2,ACTA2,SLC6A3,POLB,TOM1L2,MIR940,GREM1,VPS4B,CCNQ,TPPP,PIWIL2,ABHD14B,PXYLP1,C1QC,TRIM37,RAP2B,IRF2,SOX2,PTPN22,NFKBIB,ZNF250,TRAF3IP3,AHSA1,PAGR1,PRKCB,SHC1,RIT2,MACROH2A1,ATP2B4,NABP1,MAD2L1,CD52,CSTB,ATP1B1,CTNNA1,BAZ1B,GPX4,HBP1,CCL21,NFE2,TADA3,SERINC1,ETV6,CACUL1,MIR139,PDCD4,TES,SERPINB11,NEO1,SESTD1,STAU1,CDC23,PAFAH1B1,WDR12,TIAM1,SPOPL,HNRNPA2B1,PIK3CG,PMP22,FASLG,SCHIP1,WRAP53,BZW2,TRIM35,MIR572,GTF2H2,IL18,PBLD,LAMTOR2,CEP85,NF2,CCAR1,PRRT1,MIR455,PPM1G,SIT1,MIR298,FABP5,LLPH,ARHGEF6,TLR1,ABHD2,HSPB6,RPS12,MIR137,IL15,RASGRP3,GARRE1,CCNB1,CRYM,PCDHB13,OR7E24,BET1L,MIR493,H2AJ,ASB8,NIBAN2,ISX,STIM1,CPLX1,KCND3,MIR30E,MAGED4B,FOXP2,CCDC47,PIK3R1,MIR24-2,SETD4,NR0B1,RAPGEF5,SSRP1,PTCRA,NPC2,PRKAB1,HR,YES1,SLC23A2,CMTM7,BIRC2,EGLN3,LACRT,STAR,ASIC1,VMP1,GLUL,XPO1,KCTD10,TCEA1,PRSS8,SCYL2,PARP2,NIF3L1,CD2,SPTBN1,OR5K1,TMED9,STK11,CREB3,MED22,CCAR2,FOXA3,MAGEB1,MIR208B,SGF29,HDAC6,SAV1,MED10,ACVR1B,TMBIM6,OR4K1,ARFGEF1,PSMC1,CH25H,OPRL1,ZNF575,DCUN1D3,RDH10,CACNB4,MIR16-1,PIH1D1,DRD1,EXOC2,MAPKAPK5,ZNF805,NHERF1,MRTO4,H2AC25,DHRS11,STAT5A,CDC42EP3,PPIF,PTHLH,AKAP8L,PICK1,CSNK1A1L,GCHFR,CYP1B1,MRPL12,SGMS2,SNAP23,OR7D4,CTNND1,MRPL13,DUSP9,HNRNPDL,MMP9,PYDC2,ACAA2,PAIP1,ENPP4,GP9,BAX,TRAF3IP2,EFCAB7,MOB3B,LAMP2,CHRM4,ELF1,SLC7A1,TREML1,ERLIN2,KPNA1,FCER1G,SLC2A8,GPM6B,GPR137,EMC10,SLX1A,GNG5,MIR607,OR2AT4,MIR130B,SF3B4,MIR589,IQSEC1,UHMK1,MPV17,HMX1,FAM89B,ERRFI1,DHPS,HS3ST5,PSMA6,AKT2,VPS26B,COPS2,ATXN10,NCAPG2,CMKLR2,POPDC3,UCN,ANXA4,TAPBP,ZBTB33,MIR423,DSTYK,FOXS1,MAD2L2,GMDS,IKZF2,LPCAT3,SRD5A3,PPP1R10,GRIA2,CDKN3,OCRL,MGST2,SMG8,PPP2R5A,METTL18,MIR580,TLR9,ORMDL1,LEPROTL1,MIR196B,MT3,INPP5E,NEUROD6,NPVF,TOX,CCND3,RETN,GH1,TXN,AGTRAP,GSTP1,GRSF1,TTR,MIR675,ABCB1,CALR,SKIC8,MIR639,MIR604,APH1A,ROMO1,DKC1,WTAP,UCP2,SGMS1,MIR211,PFKFB2,MTERF2,RADX,SLCO3A1,RTF2,IFNA13,EXOSC8,TLR6,AGR2,AKT1,CLEC1A,ZNF787,RANBP1,MIR182,SLC6A1,ITGB5,HERC4,PPP3CA,MIR448,TMEM88,ZNF343,ACER3,NR1H2,E4F1,TFG,PPP5C,TSG101,KCNS1,KLRD1,UBE2D1,PSMG2,MSH6,TGFBR2,FAS,KIT,ANP32B,FLRT3,CYB5R4,TSPAN5,UTS2,DLK2,CPE,MIR1251,MET,LEPR,NEK7,ZNF362,ANAPC16,PCGF6,ZC3H7A,EHD1,MAP3K3,SYNJ2BP,AVPI1,VCPIP1,STK4,CIAO1,ST6GAL1,PPFIA3,KCTD12,SDC4,TNFSF10,MIR671,TMEM165,ARF4,APLNR,MPP1,TLR4,RPS15,KLF4,ZBED3,HOMER1,INPP4A,PIP4P1,TGIF2LX,IP6K1,LAMB2,BRINP2,LARGE1,GHR,ITGAV,ANO3,UGT1A1,MGMT,TRIP4,PCGF2,TMEM38B,ZNF574,LHX2,EIF2B2,PRIM2,GTF2I,RPS26,GPHN,B2M,RBCK1,APOC2,TRIM44,MIR638,LUM,S100B,C1QTNF1,PAPSS2,SGTA,F10,FCMR,SLC16A1,MIR503,MIR212,MLF1,DSTN,NREP,MLF2,TNFAIP8L2,PPP2R1A,TNFAIP8L3,SUFU,CHMP5,PLGRKT,NQO1,KLHL22,CD3G,CDO1,PDIA3,PDE12,RUVBL1,LRRTM2,SLAIN2,CSRP1,EDA2R,CDK8,SEC13,DIO1,TRAPPC14,BRMS1L,XCL1,SPATA4,TWSG1,CYP11B2,HMGA1,SHMT1,MIR9-2,LURAP1,PLG,MZB1,PSMD3,EMILIN1,TBC1D24,ITGB8,OAZ2,FITM1,RAB11B,RHOU,SH3BGRL,HFE,PFDN5,NSFL1C,TOPBP1,BCKDK,HSH2D,PHACTR1,ORMDL3,DDAH1,SSU72,HMG20A,MRGPRX1,TYMS,CYP11B1,TBC1D10C,CITED1,PTPMT1,RNF141,GREM2,OR52M1,MIR338,PHF12,PTGER1,GPR83,CDK9,RBM5,DRGX,NDN,CTSD,MIEN1,TBC1D16,MAPKAPK3,LYNX1,ALDH1A3,AIF1,SLC25A27,PAIP2B,CEBPG,CHST2,CXCR3,OLFML3,PPIA,CDC42,LRRTM3,TIMP3,CSNK1E,RTRAF,MAGEH1,MMUT,MIR200A,MOSPD1,DEFB124,RAB4A,ZNF821,MIR942,ADD2,SRSF12,BTN2A2,RFX4,TLCD1,IL6ST,GTF2F2,BARX2,CDNF,MAB21L1,SCG2,LILRB1,CNTFR,FRZB,ID1,YWHAH,ATP5F1A,CCL3,SEPTIN7,STAMBPL1,CDKN2AIP,RPS9,PLCXD3,MYORG,ZBTB17,DEPDC1B,SHC3,MAVS,SSH3,FURIN,TMEM101,KANSL3,MIR876,FASTKD5,EEF1E1,DOK4,TYROBP,MIR661,OR9I1,TULP3,ZNF436,TRIM54,TAF5L,SERPINB10,MRLN,BEND6,HTRA2,SPOP,IL20RB,TLE1,FBLN5,LTB,DEFB1,GTF2B,NEDD8,PIANP,MIR597,MIR346,CST11,PPY,MIR1226,RNF167,CXCL1,BHLHE40,HCFC2,ZNF345,CCR6,FEM1B,RABL3,FAM20C,MIR25,CMTM6,CA8,MIR517B,SPINT2,OR14J1,MIR30D,COL3A1,IGFBP4,OR4N4,ANKRD49,MAP3K14,TOB2,STPG4,MIR511,PPP1CC,KDM1A,OS9,GAD2,RGMB,EDF1,IL5,RASGRP2,NHP2,TLR7,RAB13,SF3B5,SLC25A14,CHST11,DLG1,ZCCHC7,CBLN1,PDF,TMEM168,OR4K13,MCHR2,CCR5,ABITRAM,STAT2,HCST,MIR551B,EXOSC4,STK16,TRIM45,SERINC3,DOK5,MIR7-3,MED17,PLCL1,RNF146,MIR601,KRIT1,CD200,WIF1,MCM3,POLR2G,CBLL1,ZNF175,STAC3,CALY,EIF1B,GNG2,MIR765,MGARP,KCNJ11,SST,FAM162A,UBASH3B,LPXN,SRSF4,DRAP1,MIR549A,TMEM199,EI24,TFE3,GOLGA7,SLITRK1,SMARCB1,EFHC1,TCP11L1,MT1A,MPV17L2,NCDN,PRMT6,COX17,NFE2L2,DNAJB4,TRNP1,EIF4EBP3,MYT1L,BORCS5,MIR563,CCDC3,TOMM7,TAAR1,TRIM3,GSTO1,MIR625,GTF2IRD1,OR13A1,CLTRN,TUSC2,SERPINB1,PIK3AP1,SLITRK2,MIR920,CRTC2,STC1,NT5C2,ALKAL1,CDH8,LMBR1L,STK38,ADIPOR1,PSMA1,NFKBIL1,PKNOX1,RPS7,OR4S2,MACROH2A2,ANAPC13,OTULIN,CCL23,MIR23B,RINT1,GNB1,TMIGD1,PABPC1,ALOX5AP,GNA11,MYL12A,IL15RA,MIR141,TERT,SNAI3,CRADD,PML,TFCP2,TASL,CTLA4,JPT2,RAB35,SFTPD,H2AZ2,CAMK2N2,VPS16,UBLCP1,FXR2,MARCKSL1,GADD45A,NEK2,CD2AP,DNAJC7,PLN,BTG1,ZNF267,CRMP1,ERP29,KBTBD13,CSK,ABHD6,MIR633,BRAP,LDB2,RNASEL,LRRC4,THRAP3,NPBWR1,PELI1,PPARA,SNAP91,RXRG,TRAF7,VEGFC,GAL3ST4,PPP4C,GRM1,MIR10A,NEUROD2,ZNF263,LDLR,AURKAIP1,TRPC1,OTX2,PRL,NCKIPSD,LIG3,FGFBP2,HYPK,FERRY3,FOXD3,SYN3,IREB2,SLC32A1,BAP1,PMAIP1,RBBP9,TTC23,PC,TSPAN18,MED29,MIR21,FGFBP1,CACNG3,COX7A1,CXCL3,RPS2,DHRS4,ELP6,WDR82,ANAPC2,ELAPOR2,MAEA,SYNCRIP,UBE2B,GLIPR2,CD99L2,PROS1,TSPAN17,CREBL2,DNM2,MIR330,COPS7B,GPT,CYFIP2,CTNNB1,SLC1A1,MIR1227,HYAL2,CD164,PACSIN3,CAMK2G,ASB3,SEMA3C,ARHGAP15,SMAD4,LSM4,MAPK4,VPS26A,ASZ1,NDNF,P2RY4,UBE2V1,MIR1271,BRS3,SLC4A8,SMCHD1,ABCE1,LACC1,TMEM215,TEX261,CAND1,TTI2,VLDLR,LRP6,MORF4L1,FBXL19,MIR500A,PTEN,JAK2,LMO2,DTD2,APOC4,SLC8A1,UBE2N,CARTPT,NCOA5,CYP2C8,NUP153,SS18,CRISP1,UBE2M,MIR155,ATP5IF1,MIR221,IL22,RLN2,HPF1,TNFSF13,CREBZF,MIR377,CDC42EP2,RIOK2,GRIA1,LMO4,OR4D2,UBE2D3,OR8B12,ITGA6,SCN1B,AZI2,SVBP,ARF1,RRAS2,CTSC,CHST10,CCNY,MIR133B,MRGPRX4,LPAR1,RRAGA,DNAJC2,MIR586,EYA3,CCL8,NKIRAS1,CHMP1B,SRSF1,P2RY1,NKAP,TSHR,PRDX2,PSENEN,ADCK1,MIR554,EZH2,IL3,UPF3B,RPS20,EIF4H,MIRLET7G,PNPLA4,IL34,OR2Y1,AP1AR,MIR28,CUL2,MNAT1,PTGDS,FSTL1,CCDC22,SRARP,CLSTN3,PPARG,SLA2,PRKCQ,PGR,TMEM237,UFD1,MIR193A,RABIF,F11R,PPP1R1B,RAB11A,CDKN2C,PAQR8,CX3CR1,CCM2,CACNB3,SLC39A10,MIR611,MIR636,MAP3K11,DDRGK1,CRLF3,NAA15,LRRC24,OR2W1,PYCARD,CD226,HNRNPH3,BCCIP,OR2H2,CXCR4,VPS28,CDC42SE2,SSBP4,CXCR1,PTK7,MPIG6B,RGS2,CD1D,MAPRE2,BCL7B,HMGB1,GABRB3,FEM1A,ABHD17A,ZDHHC8,CGAS,VIPR1,ADNP,CTTN,NFE2L1,GUCY1B1,TRA2B,SH3GLB1,HAPSTR1,GLRA2,ELOVL6,TBC1D19,INPPL1,RELL1,DCUN1D1,TBC1D13,PLSCR1,BCL7C,SLC35B4,HSD17B1,TMEM126A,CDH11,PIP4K2C,PPIH,EDEM2,EIF4E2,CD1C,TBC1D5,RAD23B,PRKCA,BRD3,LMAN1,DAPK1,ZSWIM7,CDC20,MIR142,ATP1B3,MIR184,MIR126,RIMS3,PHF13,DLX1,PREPL,CASK,GDI2,CTDSP2,ZMYM3,EED,BTF3,NFIL3,DDT,ATP6AP2,OR4K2,CDK1,OSR2,MIR105-2,APOBEC3D,ZYX,PIM2,CNPY4,OR10G7,AGAP2,NDUFA4,CDIP1,MTG1,MEAF6,PPP1CB,ADGRL3,MEPCE,MCOLN1,PRDX4,SOCS3,RBBP8,PTN,GPR22,MTM1,TNKS2,GJC1,APOBEC3F,UBE2I,ZNF687,ZHX1,MIR324,CLDN1,MIR342,SLC38A3,SERPINB6,RBM22,OR10A4,CYP2D6,ADAMTS1,CPT2,TF,IRF6,RIT1,IL1A,KRAS,MBD5,PAK1IP1,DPY30,JCHAIN,CCL20,CYTH4,ZNF177,KLK3,DDIT4,GSTM2,ATP6V1G1,FABP7,SELENOM,CEACAM5,CLRN1,CDCA7L,SUMO1,HNRNPC,RNF126,CRHR1,SETD3,IDH1,LTA,ORC5,MIR1260B,RETREG3,ACTN4,MIR425,SMAD1,IRF7,RER1,PYM1,PICALM,LITAF,ADAMTS20,CSTA,MTF1,FAM3A,FEN1,AIP,CTNNA2,TRIM22 |
| 4.564e-05 | -9.99 | ULK1 (unc-51 like autophagy activating kinase 1) | protein interactions | 8408 | 139 | 61 | 19454 | 5460 |
EXOC8,HSP90AA1,NLRP3,YWHAZ,OTUD7B,ATG101,JPT1,C9orf72,TRIM32,RALB,STK38L,ESR2,DAPK3,LDHA,TRIM27,BAD,OPTN,STAMBP,SDCBP,NLRP6,GABARAPL2,PRKAB1,ATG16L1,NRBF2,CLU,GABARAP,FLCN,ATP5F1E,BIRC2,SQSTM1,IRF3,RB1CC1,STAMBPL1,MAP4,STYK1,MUL1,EXOC2,PEDS1,BECN1,TRAF6,YWHAG,HDAC6,ATG9A,ATP5PD,HSP90AB1,HSBP1,GJA1,MAP1LC3A,SESN2,JOSD1,PRKAG1,H2AX,MAP1LC3B,GABARAPL1,TOP3B,TBK1,TP53,G3BP1,TRIM21,RAB1A,ATP5PF |
| 4.564e-05 | -9.99 | APOO (apolipoprotein O) | protein interactions | 79135 | 139 | 61 | 19454 | 5460 |
SFXN1,NSDHL,EMC2,CLPB,FLOT1,CENPM,E2F4,HSDL2,SNAP29,TMEM126A,SPG21,TIMM8A,TRAF2,NDUFS3,ACTR2,GPD2,SLC25A24,OCIAD2,COX4I1,PHB1,AIFM1,SLC25A12,TOMM70,NDUFS8,COX5A,SLC25A46,STOML2,LRRC40,SMIM12,NDUFB8,UQCC6,HAX1,RPA3,TMEM126B,NUBP2,BIRC2,PHB2,UFL1,NDUFS2,HIGD2A,UQCC3,TIMMDC1,MTX2,TIMM29,NDUFAF3,TIMM13,SAMM50,HSP90B1,COX6C,RPA2,CYC1,NDUFA5,CHCHD6,SLC25A4,NDUFAF4,PARL,CHCHD3,CEP85,COX6B1,NDUFB10,CHCHD4 |
| 4.569e-05 | -9.99 | SCAMP2 (secretory carrier membrane protein 2) | protein interactions | 10066 | 125 | 56 | 19454 | 5460 |
PLD3,STX12,AQP3,RPN1,TFRC,TP53,ATP5PB,SNAP23,LPAR2,BSCL2,ATP5PF,P2RY1,LAMP3,TMEM208,RAB5C,ATP5MG,LAMP2,SYNJ2BP,ATG9A,RAB11B,STX6,PHB1,HRAS,GOLGA5,SYNDIG1,GPR35,CFTR,TOMM22,RABL3,SYNGR2,TSPAN5,STX7,GPM6A,LPAR1,RAB5A,RTN4,RAB9A,VIPR1,TSPAN15,JAGN1,NAPA,NRP1,LRRC8C,SLC6A4,RAB11A,RAB2A,VIRMA,GNB1,ATP5F1B,RAB14,RETREG3,SYNGR1,MOG,VAMP3,CCNF,LMBR1L |
| 4.608e-05 | -9.99 | WBP4 (WW domain binding protein 4) | protein interactions | 11193 | 103 | 48 | 19454 | 5460 |
ZNF207,SNRNP70,DDX23,DNM2,SNRPD3,ZBTB2,DHX15,RBM42,PPIA,DHX38,WBP11,EZH2,SNRPE,ARGLU1,PABPC1,EWSR1,HNRNPK,LSM4,KRAS,NONO,SNRPB,TIA1,PRPF31,H2BC9,LSM6,RIT1,PSPC1,DOK4,CPSF1,SF3B4,SNRNP40,MED17,BUB3,SNRPN,SF3A1,WDR83,SNRNP27,TFIP11,RARS1,PRPF4,FAM50B,SNRPA,SQSTM1,EP300,SF3B1,RBM22,EIF5B,COIL |
| 4.608e-05 | -9.99 | PLPBP (pyridoxal phosphate binding protein) | protein interactions | 11212 | 103 | 48 | 19454 | 5460 |
ARFIP1,STK26,EIF4E,PAFAH1B2,NME4,TRA2B,UBE2K,PRCP,PPP1R2,GTF3C4,ASRGL1,PCK2,PIH1D1,CAV2,HEXB,MAP2K1,ISOC1,CMBL,SMU1,GGH,TUFM,ANAPC15,PAPOLA,CARS1,STK38L,COP1,CHORDC1,DNAJB4,NAE1,SATB1,SLC25A32,SOX2,CENPM,TMEM101,CDK5R1,CAPN2,NDUFS3,OXNAD1,GPX7,FAHD1,MYEF2,TOMM70,SUMO3,FCGR2A,HNRNPA1,CFC1,WWP2,AHSA1 |
| 4.624e-05 | -9.98 | DCAF13 (DDB1 and CUL4 associated factor 13) | protein interactions | 25879 | 217 | 88 | 19454 | 5460 |
TXNDC12,SPCS1,PRDX2,STAT1,TXN,PPP1R10,EZH1,CTTN,OPTN,RPS3,PSPC1,PTEN,RPS12,DCAF4,FTSJ3,ATG3,MECP2,CCT2,DNAJB6,PFDN6,PEA15,HSP90AA1,CIAO1,MYC,RPS29,PCCB,NONO,FTSJ1,STAU1,PSENEN,RPS15,AATF,FTL,SIRT7,RPA3,EXOSC4,RPA2,NUFIP2,UTP15,EHHADH,WDR83,NDE1,MTF1,POLR1D,TOP1,PRNP,TCP1,NOB1,RPS16,NOP58,FAM98A,CCT7,CDK9,KRR1,RPL8,PWP2,EED,DCAF5,UQCR11,NDC80,IFI16,ZMYND11,MRPL9,PPIL4,FN3KRP,NOC4L,NEDD8,KRAS,MEPCE,SNIP1,S100B,PDIA6,FAM76B,RPL23A,EXOSC3,GNPDA2,DDX42,TAF2,TMEM14B,AP1S2,RPS11,TP53,CCT5,H2AJ,RPS7,EXOSC8,LBH,JUN |
| 4.625e-05 | -9.98 | choroid_plexus_papilloma | COSMIC cancer mutations | choroid_plexus_papilloma | 8 | 8 | 16828 | 4835 |
PTPN11,IDH1,NF2,IDH2,CTNNB1,TP53,SMARCB1,TERT |
| 4.625e-05 | -9.98 | central_nervous_system-choroid_plexus-other-choroid_plexus_papilloma | COSMIC cancer mutations | central_nervous_system-choroid_plexus-other-choroid_plexus_papilloma | 8 | 8 | 16828 | 4835 |
TERT,SMARCB1,TP53,CTNNB1,IDH2,NF2,IDH1,PTPN11 |
| 4.630e-05 | -9.98 | lytic vacuole membrane | cellular component | GO:0098852 | 446 | 168 | 19108 | 5553 |
CTSA,AP2S1,DPP4,UBA52,RRAGB,ABCB9,TASL,TFE3,RNF152,VPS33A,RAB2A,ENTPD4,RHEB,NCSTN,B4GALT1,MIOS,CD164,DNAJC5,ATP6V0B,KICS2,TMBIM1,GNAI3,RNASEK,VLDLR,AP1M1,AP2A1,CYBRD1,TRIM23,STARD3NL,ATP6V1D,RAB3D,TAB2,TMEM106B,SURF4,TM9SF1,BORCS5,PLEKHF1,BORCS7,LAMP2,SLC7A14,VAMP8,CD1D,PIP4P1,SNAP29,VAMP1,ATP6V0E1,GNAQ,NAPG,UBXN6,CFTR,STOM,ATP6V1C1,CD1B,STX7,ABHD6,MITF,SNX14,MARCHF9,SLC11A2,CTSD,LAMP5,EEF1A1,BST2,GNB4,RAB14,RRAGA,KXD1,AP5M1,LITAF,PSEN1,RNF167,TMEM179B,MINAR2,BORCS6,LAMTOR3,SLC35F6,GPR137,LAPTM4A,WDR11,DRAM1,VPS39,GNB1,RAP1B,TLR8,ATP8A1,OSTM1,ATRAID,HSPA8,MMD,LAMP3,ACP2,TLR9,SPHK2,PCSK9,AP2M1,CPNE1,ATG16L1,CHMP4C,CDIP1,FCMR,TLR7,LAMTOR2,SESN2,TMEM74,MYO6,SNAPIN,CHMP2A,MCOLN1,BORCS8,ATP6AP2,VTI1B,CHMP1A,RAB5C,SLC2A8,BRI3,CMTM6,CLCN6,TMEM59,ENPEP,CYB561,SLC48A1,TRAF3IP3,FLOT1,PIP4P2,TLR3,PRCP,KLC2,SEC13,VAMP7,TMEM45B,CD63,PLAAT3,TFEB,TMEM165,LRRC8A,BLOC1S2,GNA11,PLD3,TMEM203,STX17,GLIPR1,CHMP2B,TMEM30A,ATP6V1A,CHMP1B,SLC38A7,RAB37,LDLR,SLC38A9,AP1S2,B2M,VPS18,LAMTOR1,TOM1,SLC17A5,LMBRD1,NEU1,FLCN,SYNGR1,ATP6V1G1,SAR1B,EVA1A,MREG,HPS6,VPS16,NDUFC2,CHMP5,AP5S1 |
| 4.630e-05 | -9.98 | lysosomal membrane | cellular component | GO:0005765 | 446 | 168 | 19108 | 5553 |
ENTPD4,RHEB,B4GALT1,NCSTN,MIOS,CD164,DNAJC5,CTSA,AP2S1,UBA52,DPP4,RNF152,RRAGB,ABCB9,TFE3,TASL,RAB2A,VPS33A,RAB3D,ATP6V1D,TAB2,TMEM106B,TM9SF1,BORCS5,SURF4,KICS2,ATP6V0B,TMBIM1,GNAI3,AP1M1,AP2A1,RNASEK,VLDLR,TRIM23,STARD3NL,CYBRD1,GNAQ,NAPG,ATP6V0E1,STOM,CFTR,ATP6V1C1,CD1B,UBXN6,BORCS7,PLEKHF1,SLC7A14,LAMP2,PIP4P1,VAMP8,CD1D,VAMP1,SNAP29,RAB14,RRAGA,KXD1,GNB4,BST2,PSEN1,RNF167,MINAR2,TMEM179B,AP5M1,LITAF,LAMTOR3,BORCS6,SLC35F6,SNX14,SLC11A2,MARCHF9,ABHD6,STX7,MITF,LAMP5,CTSD,EEF1A1,ATP8A1,OSTM1,ATRAID,TLR8,RAP1B,MMD,ACP2,LAMP3,HSPA8,TLR9,CPNE1,ATG16L1,AP2M1,PCSK9,SPHK2,GPR137,LAPTM4A,DRAM1,WDR11,GNB1,VPS39,BORCS8,ATP6AP2,VTI1B,CHMP1A,RAB5C,SLC2A8,FCMR,CHMP4C,CDIP1,SESN2,TLR7,LAMTOR2,TMEM74,MYO6,MCOLN1,CHMP2A,SNAPIN,CD63,TMEM45B,SEC13,VAMP7,TMEM165,PLAAT3,TFEB,LRRC8A,GNA11,BLOC1S2,TMEM59,BRI3,CLCN6,CMTM6,CYB561,SLC48A1,ENPEP,FLOT1,PIP4P2,TRAF3IP3,KLC2,TLR3,PRCP,TOM1,SLC17A5,LAMTOR1,FLCN,LMBRD1,NEU1,EVA1A,MREG,SAR1B,SYNGR1,ATP6V1G1,CHMP5,NDUFC2,AP5S1,HPS6,VPS16,CHMP2B,GLIPR1,STX17,ATP6V1A,TMEM30A,CHMP1B,TMEM203,PLD3,SLC38A7,RAB37,SLC38A9,AP1S2,LDLR,VPS18,B2M |
| 4.632e-05 | -9.98 | C-type lectin receptors (CLRs) | REACTOME pathways | R-HSA-5621481 | 144 | 68 | 10285 | 3229 |
PSMD14,KRAS,PRKACB,UBA52,SYK,CD209,UBB,RAF1,PSMD10,PSME1,SRC,UBA3,SKP1,NFKBIA,EP300,PSMD7,FCER1G,PSMA4,NFKB1,PSMB10,PSMA5,PSMC5,PSMB11,FBXW11,CLEC6A,PSMB6,PSMA2,PSMB3,PSMB7,PSMD3,PSMB1,AHCYL1,TAB1,PSMB5,PSMA3,PSMC4,PSMC3,PSMA1,IL1B,RPS27A,UBE2M,PSMD4,PPP3CA,PSME2,UBE2D1,IKBKB,PSMB4,CLEC7A,PAK2,TRAF6,PSMD6,SEM1,PSMB9,HRAS,ICAM3,UBE2V1,PYCARD,PSMB2,PSMD1,PSMA6,MAP3K14,TAB2,BCL10,ICAM2,PSMC1,UBE2N,CREBBP,PSMD12 |
| 4.670e-05 | -9.97 | SLC25A6 (solute carrier family 25 member 6) | protein interactions | 293 | 371 | 139 | 19454 | 5460 |
TXNIP,TRIM23,RC3H2,SMAD2,UBE2H,RPL7A,FBXO7,AR,KLK9,NDN,RPL10L,SLC25A4,PRKCE,SH3BGRL,SRC,VIRMA,TRAF1,CCNF,CHRM4,PRSS8,KLK6,CALML5,TRIM24,PTEN,RPA2,CTDSP1,LMNA,FGFR1,METTL14,GRM2,HEXIM1,CDC42,UQCRC1,GABRA1,CDK7,CFTR,NF2,TOMM20,HSPA5,INPPL1,RPA3,RNF113A,SNRNP70,TMEM70,FAM187B,BRD3,RPL10A,KARS1,DPP4,EMC4,PMM2,COPS5,HDAC6,FZR1,CAND1,TFCP2,SLC25A20,FURIN,NUPR1,SLC25A24,KBTBD4,FBP1,UBL4A,TP53,H2AX,MGARP,MAP1LC3B,HUWE1,TNFSF8,PAGR1,SOCS2,MEPCE,PSMB10,RIGI,MAP1B,GLUL,LRRN4CL,COP1,MYC,CUL3,BTF3,BAG3,RPL10,MAD2L2,CD79B,DLST,DKK3,SMU1,AP2M1,CRYAB,PPT1,PRSS23,PIH1D1,TIMM10,TOMM22,ASB8,FBXO42,TIMM13,NPTN,UCHL3,EMC1,UFL1,ADRB2,COIL,TMEM106B,HDAC5,NMRAL1,HSPA8,THBS3,EP300,RAB5A,AGR2,PDCD1,AHSA1,MGMT,HSPB1,NDUFB8,DDRGK1,MAP3K14,RAMP3,ELK1,PHB1,VAMP2,EZH2,AQP3,CHMP4C,SDR16C5,B3GNT2,TUBA1A,ISG15,SOX2,G3BP1,VDAC1,OSTM1,PLSCR1,SLC25A5,NDUFA4,COX8A,TRIM11 |
| 4.672e-05 | -9.97 | ERCC8 (ERCC excision repair 8, CSA ubiquitin ligase complex subunit) | protein interactions | 1161 | 114 | 52 | 19454 | 5460 |
HNRNPD,POU5F1,IFNK,COPS5,ZNF24,PFDN5,MDM2,CCT7,RPS10,COPS7B,RPS16,TOP1,TCP1,S100A8,COPS2,FABP5,AIP,SSBP1,PSMB5,TUBB4B,CCT5,TP53,RPSA,PFDN1,COPS4,PCNA,RUVBL2,DNAJB4,BAG2,DHX9,HSPD1,ATF3,CCT8,PFDN4,COP1,PFDN2,PFDN6,CCT2,PSMD1,FBXO44,OGG1,COPS7A,UQCRQ,CSNK2B,PRMT5,GTF2H2,EIF3K,PRKCA,UBE2M,RPS15,HSPA8,RPS28 |
| 4.672e-05 | -9.97 | UIMC1 (ubiquitin interaction motif containing 1) | protein interactions | 51720 | 114 | 52 | 19454 | 5460 |
DLST,CDPF1,ALB,UBA3,ESR2,UBB,CUL3,CREBBP,USP13,PPP1CC,BRCA1,RBBP8,PML,WBP2,RPA3,LIN7C,RFC4,DVL2,NOP53,G3BP2,SUMO1,RPL27A,CCNA2,RPA2,CDK1,SSU72,TNKS,COPS2,SUMO2,CPNE1,MDM2,DPY30,RIOX2,BABAM1,MOV10,F7,SPATA2,THNSL1,NAE1,LDLRAD4,H3C1,G3BP1,FANCG,MDC1,CAPZA1,TNKS2,TP53,COMMD8,ZMYM3,H2AX,CBX3,CASK |
| 4.717e-05 | -9.96 | RABL3 (RAB, member of RAS oncogene family like 3) | protein interactions | 285282 | 159 | 68 | 19454 | 5460 |
DNAJC25,FURIN,KDELR1,RAB4A,RPN1,STIM1,TMT1A,CYP2C9,FKBP8,ARF4,RAB3B,KRAS,LAMP3,SLC25A46,TMEM208,RAB5C,RELL1,LAMP2,ESYT1,RHOG,RAC2,HSD17B11,LHFPL4,GJA1,RAB35,PTPN1,CAV1,TMPO,STX6,EGLN3,LMAN1,DNAJC1,ST7,SEC62,CDC42,RND2,OTULINL,YIPF5,BET1,PTAR1,SIGMAR1,STOM,SSR1,LMNA,RAB9A,DERL1,RAB5A,FLCN,SYVN1,TSPAN15,STX7,PXMP2,CAV3,CIAO1,RAB11A,SLC35C1,LMNB1,GPR173,GPR89A,SEC61B,RMDN3,SYNGR1,SCAMP2,LMBR1L,CCNF,SEC63,ATP6AP2,ESR2 |
| 4.718e-05 | -9.96 | UBE2A (ubiquitin conjugating enzyme E2 A) | protein interactions | 7319 | 223 | 90 | 19454 | 5460 |
PCNA,CDK5,HECTD3,HNRNPA2B1,HNRNPDL,UBE2A,AP1M1,ZBED1,RPS23,NFKBIL1,CTNNA2,BRD9,GJA1,TYMS,TNIK,DHX15,ATXN10,FAM98A,EIF3D,PRPF19,PSMD3,RPL23,HNRNPD,UCHL3,CD59,RPS9,RETREG3,ZMYM2,CBX5,RBBP4,RPL35,TAX1BP1,SNRPB,TOMM40,RNF40,HNRNPC,NSA2,CRMP1,FTSJ3,POMP,CPNE2,RNF167,ABHD10,OLA1,RNF20,CSE1L,THRAP3,H3C1,UBE2V1,LBR,TP53,JPH4,GNAI3,UBE2B,PSMB1,TES,RPL12,SSBP1,SYNCRIP,SRP14,MDM2,CDK9,SHPRH,CSNK2A1,RPL10A,SMCHD1,NBN,RPA3,NF2,NPM3,EIF5B,CNP,CD2AP,UBA52,TPT1,GSTP1,SDCBP,RPA2,CDK1,ACAT1,TRIM27,CTNNA1,EIF4A3,CCNF,UQCRC2,UBE2L3,UBB,BUB3,NONO,PSMB2 |
| 4.718e-05 | -9.96 | GSX1 (GS homeobox 1) | protein interactions | 219409 | 46 | 26 | 19454 | 5460 |
NAA50,NDUFAF2,PDCD10,ZMPSTE24,VAMP3,CYB5R3,EFHD2,CDCA3,HSBP1,DUSP3,NUP35,LYPLA1,FEN1,APOO,DHRS4,BCS1L,NRN1,RPRD1B,CRABP2,PPID,DCUN1D5,PTRHD1,PYM1,PSMG4,YKT6,SAR1B |
| 4.724e-05 | -9.96 | RB1 (RB transcriptional corepressor 1) | protein interactions | 5925 | 368 | 138 | 19454 | 5460 |
EPO,PPARG,CTBP1,MED23,CDKN1A,PPP1CB,CCND3,EP300,HSPA8,FOS,HSP90AA1,SP1,LMNB1,BRCA1,RBBP8,TFDP2,FAS,ELMO2,MCM4,LDB1,RNF40,RFC5,CUL3,PIK3R3,LMO2,MYC,ESR2,CBX5,UMPS,RBBP4,STAT1,ANAPC2,VEGFA,SMARCB1,HDAC11,EZH2,ELF1,JUN,TUBA1A,RBBP9,E2F4,RAF1,VDR,PAX6,HNRNPDL,PCGF6,MCM6,CCAR1,TRMO,PCGF3,RBBP7,ZBTB16,CHN2,CDK5,RINT1,PPAN,FKBP4,KDM2A,PSMD10,NDC80,DYRK1B,PIK3R1,PPIA,MITF,PHB1,STAT6,CCL19,E2F6,STX17,RPA2,CDK1,FBP2,LMNA,RPRD1B,CCNA2,PRMT2,CCND1,AATF,HMGB1,HDAC3,KDM1A,PPP1R26,PRKCB,SIRT7,PML,IRF3,PNO1,SNAPC1,HERC4,TADA1,PPP1CC,AR,CCNB1,MORF4L1,FOXA3,CDC16,TAF5L,NMI,DYRK1A,CEBPE,UBE2I,PRKRA,TRIM27,PELP1,BIRC5,HBP1,ENC1,CBX3,PLA2G12A,GBE1,TP53,CDK4,MTA3,UBL4A,FBP1,MNAT1,GALNT12,MRPS18B,MRFAP1,RING1,HAPSTR1,SNAPC3,ATP5PF,BGLAP,SHC1,EID1,E4F1,SUV39H1,COMMD5,CSNK2A1,CITED1,MDM2,CDK9,TMPO,THOC1,FZR1,RB1,CDK6 |
| 4.746e-05 | -9.96 | Non-alcoholic fatty liver disease (NAFLD) | KEGG pathways | ko04932 | 145 | 73 | 7161 | 2463 |
UQCRC2,SDHB,COX5A,NDUFC2,COX7B2,PRKAB1,COX6B1,IL6,ADIPOR2,IL1A,NDUFA2,NDUFB4,NFKB1,FAS,DDIT3,AKT3,NDUFB10,ADIPOR1,NDUFB6,NDUFV2,XBP1,CXCL8,GSK3A,ATF4,CYC1,UQCRH,LEPR,COX6C,COX7A1,NDUFA5,COX4I1,PIK3R3,COX7B,PIK3CA,NDUFB5,TNF,NDUFA12,PRKAG1,NDUFA4,BAX,IL1B,JUN,AKT2,NDUFAB1,NDUFS6,COX8A,NDUFB8,EIF2S1,SDHC,NDUFS3,COX6A2,NDUFS2,ADIPOQ,NDUFB7,UQCR11,MAPK10,PPARA,TRAF2,IKBKB,FASLG,UQCRQ,NDUFA1,LEP,NDUFS8,SOCS3,PIK3R1,COX4I2,AKT1,UQCRC1,MAP3K11,CDC42,COX6B2,PIK3R2 |
| 4.746e-05 | -9.96 | Non-alcoholic fatty liver disease (NAFLD) | KEGG pathways | hsa04932 | 145 | 73 | 7161 | 2463 |
TNF,PIK3CA,NDUFB5,IL1B,NDUFA12,BAX,NDUFA4,PRKAG1,PIK3R3,COX7B,EIF2S1,NDUFS3,SDHC,NDUFAB1,AKT2,JUN,NDUFB8,COX8A,NDUFS6,UQCR11,NDUFB7,NDUFA1,UQCRQ,FASLG,IKBKB,PPARA,TRAF2,MAPK10,NDUFS2,COX6A2,ADIPOQ,AKT1,CDC42,PIK3R2,MAP3K11,COX6B2,UQCRC1,NDUFS8,LEP,COX4I2,PIK3R1,SOCS3,PRKAB1,COX7B2,IL1A,ADIPOR2,IL6,COX6B1,SDHB,UQCRC2,NDUFC2,COX5A,FAS,NFKB1,AKT3,DDIT3,NDUFA2,NDUFB4,CXCL8,XBP1,NDUFV2,NDUFB6,UQCRH,CYC1,ATF4,GSK3A,NDUFB10,ADIPOR1,COX7A1,COX4I1,NDUFA5,COX6C,LEPR |
| 4.750e-05 | -9.95 | LIPT1 (lipoyltransferase 1) | protein interactions | 51601 | 17 | 13 | 19454 | 5460 |
KRAS,STAT2,RP2,DBT,BAP1,FOS,PALS2,SLC25A28,PRKCA,RIT1,SUFU,HPCAL1,METTL15 |
| 4.756e-05 | -9.95 | AK3 (adenylate kinase 3) | protein interactions | 50808 | 66 | 34 | 19454 | 5460 |
CFL1,ACO2,UBE2H,FXN,AK2,GATD3,ACAT1,FAHD1,CYB5R3,PPIA,TXN,SPPL3,DAPK3,TRIM54,CTSB,LGALS3,TXNDC12,TENT5C,GABARAPL2,RPS14,LYPLA1,SOD2,MSRB3,EZH2,NUDT19,DISC1,PDHA1,ACAA2,COA4,COX17,APPBP2,PTRHD1,HSPD1,ZDHHC17 |
| 4.769e-05 | -9.95 | VPS4B (vacuolar protein sorting 4 homolog B) | protein interactions | 9525 | 79 | 39 | 19454 | 5460 |
CFTR,DDX39A,PPP1R8,H1-5,PRKCA,CHMP1A,JUP,HSPA8,BIRC2,KATNAL1,RPL31,GRXCR1,RIGI,AHCYL1,VTA1,USP8,YTHDF1,CHMP1B,IL1B,KDM1A,BTF3,CUL3,BABAM1,VPS26A,HTRA2,EPHA2,VPS4A,ATP5MC1,PHF21A,IGBP1,TYMS,PHB1,CCNF,CHMP2A,CHMP5,TUBB,CGAS,RALA,TTC9C |
| 4.769e-05 | -9.95 | NUCB2 (nucleobindin 2) | protein interactions | 4925 | 79 | 39 | 19454 | 5460 |
GNAI3,FKBP10,HSPA13,TFRC,JUN,YIPF5,MGARP,GTF2H4,TIMM10,IMMP2L,CLU,HSPA5,SLC7A1,AKAP1,GADD45A,GLUL,TMEM106B,DNAJC3,NAE1,CALU,CDC73,BRCA1,DNAJC10,STAR,XPO1,CUL2,DPP4,JUNB,APEX1,NR1I2,SPTAN1,MANSC1,DNAJB9,CTSB,NDN,HNRNPL,COPE,CEBPG,SEC61B |
| 4.777e-05 | -9.95 | GNAT2 (G protein subunit alpha transducin 2) | protein interactions | 2780 | 19 | 14 | 19454 | 5460 |
GNG3,MYC,SNX5,GNAI3,ARMCX3,METTL14,GPSM3,GNAO1,ACSL4,UNC119B,SNX1,SNX2,ADRB2,EPHA4 |
| 4.784e-05 | -9.95 | schwannoma | COSMIC cancer mutations | schwannoma | 27 | 18 | 16828 | 4835 |
EWSR1,GNAQ,STK11,IDH1,KLF4,KRAS,HRAS,PTEN,SMARCB1,PIK3CA,TERT,IDH2,AKT1,NF2,ETV6,CTNNB1,GNA11,KIT |
| 4.797e-05 | -9.94 | sulfur compound biosynthetic process | biological process | GO:0044272 | 155 | 69 | 18204 | 5365 |
MGST2,CSGALNACT2,TECR,GSTA1,MTAP,CHST2,FMO3,CDO1,PDHA1,HS3ST3A1,PAPSS2,ACAT1,SLC19A2,CHST7,ST3GAL2,CHST11,ELOVL4,HS2ST1,NDST3,MPST,ELOVL6,HACD1,ELOVL7,B4GALT4,CHPF,GGT7,ST3GAL1,ELOVL1,ACACA,AKR1A1,EXTL2,B3GNT2,HS3ST1,THTPA,SLC19A3,GLCE,FMO1,ACSS2,DLAT,GGTA1,ANGPT1,EXT1,MTHFD2L,HS3ST5,CHST1,GCLC,MAT2B,UGDH,PDHB,ST3GAL4,UST,MAT2A,CHPF2,MMUT,HACD2,CHST13,PPT1,ELOVL3,CHAC2,CHST9,ACSL4,LIAS,B4GAT1,CSGALNACT1,SLC25A1,SLC1A1,GSTP1,NDST1,SLC1A2 |
| 4.822e-05 | -9.94 | regulation of metal ion transport | biological process | GO:0010959 | 393 | 152 | 18204 | 5365 |
MIR448,MIR424,PLP1,SUMO1,FGF13,CRHR1,SRI,MCHR1,CCR1,PRKCE,CACNB4,DRD1,KCNIP2,SPHK2,JPH4,ACTN4,PML,SLMAP,PCSK9,ATP2B4,MIR200C,PPP3R2,NHERF1,CXCL10,NPSR1,VAMP2,FKBP1A,CCL2,KCNS1,ATP1A2,SLC8A1,DLG1,ATP1B1,F2,G6PD,CNTN1,GNAI2,DMPK,PLN,SCN2B,CXCL11,TF,KCNMB1,LACRT,CTNNB1,BAK1,ATP1A1,VMP1,CACNB3,CX3CL1,CHP1,ISCU,MIR24-1,SCN3B,PRSS8,XCL1,CAMK2G,MIR192,PACSIN3,CD63,STC1,ADRB2,DRD3,TESC,MIR208B,CAB39,CXCR4,HECW1,AKT1,CXCL12,GSTM2,HFE,TMBIM6,RANGRF,MIR30D,PPP3CA,FXYD6,GPR35,UBASH3B,CAV3,MIR210,UCN,FKBP1B,B2M,LGALS3,EPO,KCNAB1,CLIC2,CAV1,CD4,MIR21,MIR153-1,LILRA2,OPRK1,STIM1,SELENON,MIR212,AMIGO1,GSTO1,HOMER3,TLR9,MRLN,TSPO,NOS1AP,KCNIP3,MIR208A,CNKSR3,MLLT6,MIR34A,IL13,ATP1B3,SCN1B,BAX,HPCA,MIR1-1,SESTD1,AHCYL1,DPP10,WWP2,HCRT,RCVRN,IFNG,CASK,KCNC1,CACNB2,CXCL9,CCL5,PDE4B,THY1,PIK3CG,ATF4,FGF12,APLNR,TRIM27,OXSR1,PSEN2,NETO1,HOMER1,SNTA1,PRNP,STAC3,INPP5K,HTR2A,ADORA1,TRPC1,VDAC1,LILRB1,KCNJ2,PLPP4,YWHAH,TMEM38B,CCL3 |
| 4.833e-05 | -9.94 | CTNND1 (catenin delta 1) | protein interactions | 1500 | 232 | 93 | 19454 | 5460 |
FBXW7,RPA3,SOD1,RHOU,DVL2,RNF113A,RAB9A,SQSTM1,RPA2,JUP,ATG16L1,CFTR,CDC42,YES1,SRC,DYRK1A,SMURF1,ZBTB33,CTNNA1,EIF4A3,CTTN,CCNF,GSK3A,RC3H2,SPOP,UBE2H,RAB2A,DNAJC5,ARHGAP21,CTNND1,PSEN1,CDH8,NUPR1,MIF,ARF6,CAV1,CDC5L,LMAN1,STX6,HRAS,RAC2,CDH11,KLHL22,HDAC6,LAMP3,STAU1,HSCB,STX7,RAB5A,HSPA8,PPT1,VAV2,CLDN4,RND2,FBXO22,ACTB,MATR3,AP2M1,RHOB,YWHAZ,LAMTOR1,NTRK3,CUL3,RAB11A,MYC,KRAS,G3BP1,EPHA4,FLOT1,RAB4A,MOB3C,RND3,RAF1,CSNK1E,SOX2,SUMO2,RHOH,HNRNPL,DIRAS3,EGLN3,FBXO32,RAB35,GJA1,RHOG,YWHAB,RAB5C,LAMP2,IFI16,TAX1BP3,CTNNB1,YWHAH,YWHAG,XPO1 |
| 4.833e-05 | -9.94 | H1-0 (H1.0 linker histone) | protein interactions | 3005 | 232 | 93 | 19454 | 5460 |
SMARCB1,PDHA1,EZH2,E2F4,FEN1,MCM6,VDAC1,TRIM37,RBBP7,G3BP1,TRIM11,RUVBL2,CDK5,NCK1,AGR2,MAP3K14,DDRGK1,WWP2,CDC26,HMGA1,IFI16,BAZ1B,NUP35,HP1BP3,EED,PHB1,PRSS23,MAP2K1,DET1,H1-5,G3BP2,STAU1,UFL1,HSPA8,DDX39B,DCAF4,RPS6KA4,NOA1,H1-10,MCM4,BTF3,SFN,MYC,DLST,PARP2,NUPR1,NECAP1,TP53,CDK4,H2AJ,VRK1,KPNA2,H3C1,GLCE,MAP1B,BRD3,H2AC4,MED27,DPP4,GRSF1,H2AC14,ZBTB2,TSPYL4,CGAS,PRNP,CAND1,FZR1,H2AZ1,MACROH2A2,LMNA,CDK1,RPA2,XBP1,CDK7,NUCKS1,RNF113A,PRKCB,SOD1,PPM1G,MAPRE1,RC3H2,H2BC9,FBXO7,CDC16,SMARCA5,DYRK1A,HPF1,PTEN,MACROH2A1,PRKRA,FGFBP1,LIG3,CCNF |
| 4.840e-05 | -9.94 | RPF1 (ribosome production factor 1 homolog) | protein interactions | 80135 | 128 | 57 | 19454 | 5460 |
E4F1,IFI16,RPL10A,RPS2,NOL12,SRSF1,KRR1,SRP14,RPL8,SURF6,LYAR,RPS10,RPS16,RPL15,MAK16,H1-3,MAGEB10,E2F4,RPL18,SART3,RPL23A,RPL3,RPL31,RPL17,RPL28,HMGN4,KRAS,RPL26,ZNF668,RPL7A,MYC,RPF2,H1-1,ZCRB1,LMNB1,MECP2,PRKRA,FGFBP1,RPL37A,RPL10,ESR2,RPL35,RPL13A,FGF13,RPL27A,MACROH2A2,RPLP0,RPL26L1,APOBEC3C,RPA2,EP300,RPA3,FTL,STAU1,RPL4,NPM3,DGCR8 |
| 4.840e-05 | -9.94 | ARL2 (ADP ribosylation factor like GTPase 2) | protein interactions | 402 | 128 | 57 | 19454 | 5460 |
CDC16,TBCE,CUL3,PTTG1,RIT1,SPOP,YWHAZ,ZMAT5,OPTN,ACOX1,CCNF,UBA3,PSMD4,PSMD6,TUBB,ACTL6A,PAFAH1B1,ZNF574,SCLT1,MTRES1,RPA2,USE1,PRKCB,KDM1A,PPP2R2C,HSCB,YWHAH,CENPW,MOV10,CDC23,YWHAB,RPL23,ARL2BP,RHOG,SKIC8,NCR3LG1,FAHD1,RPLP1,PPP2CB,PPIA,PPP2R1A,ANAPC13,RAF1,CENPM,TAF2,PDE6D,TUBB4B,SKA3,PDHA1,CFAP36,COX8A,UNC119B,PPWD1,PRPS1,HNRNPDL,KRAS,CTNNBL1 |
| 4.861e-05 | -9.93 | CAMSAP1 (calmodulin regulated spectrin associated protein 1) | protein interactions | 157922 | 87 | 42 | 19454 | 5460 |
ZYX,RPA3,LCA5,MRFAP1L1,TMT1A,DERL1,KDM1A,TRIM37,STAU1,TOP3B,MAP1LC3B,BORCS6,KIF2A,SMAD1,TUBB4B,STIM1,RPA2,RBPJ,TRIM36,HRAS,MAP1LC3A,GSK3A,KRT8,EGLN3,DYRK1A,VIRMA,ESR2,SRPK2,HMGA1,NDC80,SFN,YWHAG,YWHAH,YWHAZ,BICD2,STK11,MED4,SMAD9,SSX2IP,MAPRE1,CAMSAP2,YWHAB |
| 4.886e-05 | -9.93 | establishment of protein localization to mitochondrial membrane | biological process | GO:0090151 | 33 | 21 | 18204 | 5365 |
BAX,TOMM70,TOMM40,TIMM10,TRMT10B,HSP90AA1,TOMM6,TOMM7,MTCH2,TIMM13,TIMM8B,TOMM20,ROMO1,MTX2,TOMM22,AGK,SAMM50,BCS1L,MAIP1,TIMM8A,TIMM29 |
| 4.891e-05 | -9.93 | MST1R (macrophage stimulating 1 receptor) | protein interactions | 4486 | 188 | 78 | 19454 | 5460 |
CBL,DDX1,BCL2L1,YWHAB,SHC1,GK5,RPL24,YWHAH,YWHAG,TPM3,KARS1,PDIA3,PIK3R1,PFDN5,LMAN1,SURF6,EIF2S1,CORO1C,HP1BP3,SRP14,RPS11,NCR3,SRP72,GLE1,SFTPC,CAPZA2,LBR,RPL29,MAP2K3,CLEC2B,TOP3B,UBL4A,RANBP1,ARF4,POLDIP3,GJB1,ZBED1,DNAAF10,ERP29,HSP90AA1,SERPINH1,PFDN6,SDF2L1,FTSJ3,YWHAZ,H1-10,AKT1,SMARCA5,SFN,JAK2,RPL19,RPL22,GNB1,SRC,RPL35,YES1,RPS9,ST8SIA5,SF3B6,GAB1,STUB1,FAU,RPL26L1,PRKCA,AGGF1,HSP90B1,TMEM106A,HYAL2,PRKAB1,RPL27A,EEF1E1,UNC45A,FABP4,BRIX1,HSPA8,AKAP1,MTDH,DVL2 |
| 4.893e-05 | -9.93 | CPSF1 (cleavage and polyadenylation specific factor 1) | protein interactions | 29894 | 238 | 95 | 19454 | 5460 |
MIR16-2,RNF20,MIRLET7C,NUPR1,ILF2,DDX42,MIR15A,MIR200C,CDK9,MIRLET7G,TOP1,FZR1,MYBL2,MIR106B,SSU72,MIR34A,SNRNP70,MED27,PPIL4,HDAC6,COPS5,MOV10,MIR29A,MIR107,FBXW7,MIRLET7I,NLE1,PRPF4,SIRT7,MIR205,RPA3,MIR7-1,DYRK2,MIR21,RPA2,MIR1-2,PIP5K1A,MIR34B,CPSF4,VIRMA,CSTF3,PPP1R10,QSER1,CCNF,UBE2H,CDC73,AR,SSRP1,CBLL1,GTF3C3,MIR155,KRAS,FAM76B,MIR206,EZH2,CSTF2T,LGR4,RAF1,TOP3B,COPS2,MIR214,EED,FBXO32,MIR221,MIR31,CPEB1,WWP2,MIR143,TAF7,STAU1,HSCB,UFL1,TRA2B,EP300,HSPA8,SNRPA,CSNK1A1,PPP1CB,ZNF362,ZC3H14,PRRC2A,ESR2,TAF11,FBXO22,SIAH1,MIRLET7B,CPSF1,MYO6,ARHGAP19,CPSF2,SNRPB,MIR98,CUL3,PAPOLA,MYC |
| 4.904e-05 | -9.92 | MRRF (mitochondrial ribosome recycling factor) | protein interactions | 92399 | 295 | 114 | 19454 | 5460 |
MRPL20,POLDIP2,BRIX1,NME4,PDHB,MRPL17,MRPL40,MRPL41,TWNK,GFM1,DLAT,IDH3A,ZNF501,QRSL1,MRPS34,MRPL10,ATG16L1,MRPS28,ACAT1,MRPL53,OAT,MRPS16,SYP,ANAPC15,NDUFAF2,FGFR1OP2,PYCR2,FASTKD5,MRPL22,MRPS18C,MRPS33,PDE12,HNRNPK,SRPRB,MRPS18B,HSD17B10,THG1L,MRPL52,ATP5PF,MRPL49,NDUFS3,HADH,PPIF,BCS1L,METTL15,ATP5PB,NDUFA2,MRPL47,MALSU1,ATP5PD,DBT,MRPS23,MRPL24,MRPL50,SYNCRIP,MRPS9,ALYREF,GRSF1,COX5A,MRPS7,NDUFS2,ATP5IF1,HADHA,PYM1,NDUFA5,ATP5PO,MRPL12,NDUFAF3,AGTRAP,NDUFAF4,MRPL23,ATP5F1B,TRMT11,MRPL13,TACO1,DLST,MRPS25,AUH,PMPCA,PYCR1,HNRNPAB,MRM2,SRSF4,MRPS17,HNRNPDL,KGD4,ATP5F1D,ETFA,HINT2,MRPS11,FHL3,SKA1,PREPL,HSPD1,ARGLU1,HNRNPA2B1,NDUFA12,PDHA1,NDUFS6,RAF1,ETFB,NDUFS8,HNRNPL,PHB1,MRPS26,MED4,MRPL18,NDUFV2,MRPL9,PPIB,DDX50,CLPX,MRPS35,STOML2 |
| 4.908e-05 | -9.92 | carbohydrate biosynthetic process | biological process | GO:0016051 | 128 | 59 | 18204 | 5365 |
HAS3,AKT2,EXT1,PTGES3,SDS,FUT1,PGAM1,SLC37A4,AKT1,ENO1,MPDU1,FBP1,B3GALT1,ATF3,AKR1B1,ST3GAL4,LEP,PPARA,ENO2,SORD,ATF4,CHST9,FBP2,CHST10,PPP1R3C,CHST13,GBE1,CRTC2,NDST1,PGM1,G6PC3,CSGALNACT1,SLC25A1,LEPR,RGN,PCK2,SLC25A12,CSGALNACT2,G6PD,FUT8,MDH1,PGK1,PHKG1,HS2ST1,B3GALT4,CHST11,ST3GAL2,GYS1,B3GALNT1,UGP2,PC,B4GALT1,NDST3,CRY1,SLC25A11,AKR1A1,SLC25A10,FUT9,B3GALT2 |
| 4.940e-05 | -9.92 | DDX31 (DEAD-box helicase 31) | protein interactions | 64794 | 244 | 97 | 19454 | 5460 |
PRKRA,FGFBP1,ALB,ZNF330,SMURF1,RPL22,SRPK2,RPL13A,RPL26,CIAO1,RPL7A,MECP2,LACRT,RPA3,NLE1,SIRT7,CLU,DGCR8,B2M,TTR,NPM3,RPL4,KLF12,FGF13,RPS14,RPLP0,RPL26L1,MACROH2A2,GRM2,SRP14,KRR1,DKC1,SURF6,CAND1,SCGB1D1,HP,PLEKHO1,NOL12,RPL10A,SNRNP70,RPL23A,RPL3,RPL17,H3C1,TF,RPSA,JCHAIN,ILF2,SERPINA1,LLPH,RBM34,RPL37A,FAU,APEX1,RPL10,RPL19,ESR2,SNRNP40,RPL7L1,RPL35,ZNF668,MYC,H1-1,DNAJB6,RHOB,LCN1,COIL,AZGP1,ZNF692,NOP53,STAU1,RPL27A,H1-5,FGF17,APOBEC3C,SERPINC1,RPL8,SRSF1,RPS10,LYAR,DDRGK1,CST3,LYZ,LHX2,DDX23,COX8A,RPS24,RPL31,SRSF4,RPL28,HMGN4,H1-3,SERPINA3,RAF1,MAGEB10,SART3,BPIFB1 |
| 4.969e-05 | -9.91 | Glutathione-S-Trfase_C_sf | interpro domains | IPR036282 | 40 | 24 | 18521 | 5414 |
GSTM4,CLIC2,CLIC4,GSTP1,GSTM3,HPGDS,GSTA2,GSTO1,GSTM2,EEF1G,CARS1,GSTCD,GDAP1L1,GSTM5,MARS1,GSTT1,EEF1E1,GSTT2B,EEF1B2,MTX2,FAXC,GSTA4,GSTO2,GSTA1 |
| 4.982e-05 | -9.91 | GNB5 (G protein subunit beta 5) | protein interactions | 10681 | 51 | 28 | 19454 | 5460 |
GNG2,COPS5,PFDN5,CCT2,LDLR,CSNK2B,OLFM2,GNB1,CCT7,USP38,TCP1,PSMD4,CDKN1A,EIF3J,ASPM,GNG3,CCT5,GNG13,RGS7BP,MVD,ANXA7,PDCL,CTBP1,GNG7,RGS6,GNG5,FKBP8,BNIP3L |
| 4.982e-05 | -9.91 | GPATCH11 (G-patch domain containing 11) | protein interactions | 253635 | 51 | 28 | 19454 | 5460 |
SF3B5,SNRPE,EZH2,SDCBP,LMNA,SMNDC1,RAF1,SF3A1,SNRPN,SNRPG,UFL1,H1-6,PICK1,SF3B1,EWSR1,KPNA1,DNAJC8,SNRPB,RBM17,SNRPB2,DEK,RPS16,PRNP,TRIR,SNRPA1,SNRPD2,RPLP2,SF3B6 |
| 4.982e-05 | -9.91 | RNF216 (ring finger protein 216) | protein interactions | 54476 | 51 | 28 | 19454 | 5460 |
TLR4,PML,FAM168A,UBE2D3,RNF11,TICAM1,TIRAP,TLR3,TLR5,ZFAND2A,OPTN,ACTA2,UBASH3B,SUMO2,UBE2L3,DYRK1A,USP5,VIRMA,TNFAIP3,MOV10,PRKACB,XPO1,UBE2D1,BECN1,BRCA1,TLR9,COP1,UBE2H |
| 4.982e-05 | -9.91 | KIF2B (kinesin family member 2B) | protein interactions | 84643 | 51 | 28 | 19454 | 5460 |
STK3,HOMER1,COMMD6,FBXO22,DAPK3,FEM1B,STK4,RUNX1,SAV1,CDC26,DSN1,CDC16,UBE2H,CDC23,TMEM164,CCDC22,BICD2,COMMD2,MIS12,ANAPC16,SIKE1,BACH1,STAU1,COMMD3,COMMD8,SPC24,H1-5,ACACA |
| 4.984e-05 | -9.91 | synaptic vesicle | cellular component | GO:0008021 | 222 | 92 | 19108 | 5553 |
SYNGR4,SYPL1,PSEN2,ATP8A1,CTTNBP2,PPFIA2,COPS4,HSPA8,STX12,SCAMP5,DLG4,RAB3A,SYNGR2,APH1A,GAD2,SV2B,LGI3,BACE1,SNAP25,ICA1,TRAPPC4,VTI1B,SYN3,RAB5C,ATP6AP2,SYT2,RAB13,IQSEC1,RAB3C,GABRA2,COPS5,SNAPIN,ROGDI,SEPTIN6,STX1A,SNAP91,VAMP2,NTF4,STX16,SVOP,RAB40AL,HCRT,GABBR1,SYNGR1,ATP6V1G1,RAB3B,DISC1,SLC35F1,SLC17A5,PRRT1,SYNPR,PPT1,PICK1,ATP6V1A,RAB5A,DNAJC5,RAB11B,MTMR2,STX10,CPLX3,NCSTN,SLC18B1,MT3,STX6,GRIA1,SLC4A8,BORCS5,STX11,ATP6V1D,RAB3D,PDE4B,SLC35G2,ATP6V1G2,MME,ATP6V1C1,OPRK1,ZNRF1,RABAC1,VAMP1,RAB8B,SEMA4C,SLC32A1,PSEN1,SYP,BCL2L1,PICALM,STX7,SYNDIG1,LAMP5,SYNGR3,TMED9,SYT4 |
| 4.987e-05 | -9.91 | TOR1AIP2 (torsin 1A interacting protein 2) | protein interactions | 163590 | 191 | 79 | 19454 | 5460 |
CCNF,LMBR1L,SEC61B,RMDN3,RHOJ,SEC63,SH3BP4,APLNR,COPS7A,LMNB1,TMEM106B,RAB5A,RAB9A,DERL1,TXNL1,SYVN1,HSCB,ARL6,PXMP2,STX7,CCND1,SLC16A10,TIMM29,ST7,TMEM106A,OTULINL,CDC42,SEC62,DDX4,SSR1,LMNA,ACACA,PHB1,FBXO32,PTPN1,ACSL4,NDUFA1,RAC2,TES,EXT1,HSD17B11,TCP1,DNAJC1,ARF6,TOR1B,PXYLP1,LMAN1,TMPO,RAB5C,SLC25A46,USP3,EMC4,FAM174A,FAM20C,SYNJ2BP,LAMP3,COPS5,XPO1,ESYT1,RHOG,RPL23,RPS2,TMT1A,CYP2C9,SLC20A2,RAB3B,TRIM63,KRAS,SLC25A14,COPS4,RAD21,TP53,B3GNT2,DNAJC25,SFTPC,RAB4A,STIM1,RPN1,CYB5B |
| 4.987e-05 | -9.91 | EXOC4 (exocyst complex component 4) | protein interactions | 60412 | 191 | 79 | 19454 | 5460 |
RALB,SYCE3,MYC,RAB11A,GPR17,SMARCE1,EXOC5,LAMTOR1,EXOC8,CCHCR1,CCNF,LMBR1L,DLG4,RRAS2,ANAPC2,PHF21A,RALA,APLNR,ESR2,VIRMA,PTAR1,ATG16L1,CFTR,BORCS6,RPA2,FGFR1,SCLT1,HECTD1,RPA3,CXCR4,TRIM5,AKAP1,SQSTM1,KDM1A,FBXW7,STAU1,KRT222,STX7,MBD3,NFKB1,DPP4,KXD1,NDC80,YWHAH,YWHAG,INSYN1,EXOC1,TPM3,DDRGK1,H2AC4,EXOC2,BECN1,MED4,GJA1,DLGAP4,HNRNPL,ATP5PD,STX6,CNTROB,EGLN3,CAV1,CDC5L,TOP3B,COMTD1,SNAP29,DLG3,IL1R2,ING1,GTF2E2,EXOC3,SCHIP1,TFRC,RAB4A,DISC1,SIKE1,POC1B,KRAS,STX11,CAPZA1 |
| 5.002e-05 | -9.90 | NOC2L (NOC2 like nucleolar associated transcriptional repressor) | protein interactions | 26155 | 274 | 107 | 19454 | 5460 |
ILF2,FURIN,NUPR1,RBM34,RPL15,KBTBD4,TP53,RPS13,RPL17,RIGI,RPL3,CPNE2,SNIP1,RPL10A,H2AC4,MPG,DPP4,MOV10,PLEKHO1,MDM2,DKC1,FZR1,SRP14,RCHY1,EEF1AKMT3,RPL26L1,RPLP0,MACROH2A2,WTAP,RPA2,FGF13,RPS14,AATF,NPM3,DGCR8,FBXW7,RPL4,DERL1,RPA3,RPL27,SNAPC1,PML,SIRT7,NLE1,NOG,PTTG1,ZBTB38,UBE2H,MECP2,RPF2,RPL7A,SRPK2,RPL22,RPL13A,PRKRA,FGFBP1,PTEN,EIF2AK2,ZNF330,RPL18,EZH2,RPN1,CHMP4C,MAK16,TOP3B,MAGEB10,RPL28,GOLGA7,KRAS,H1-6,JAK1,RPS24,RPL31,FGF3,DDX23,PPIB,XPO1,MAP3K14,DDRGK1,UBXN6,IFI16,DHX15,LYAR,EED,RPL8,MRTO4,APOBEC3C,MAP2K1,SYK,MTF1,COIL,STAU1,DNAJB6,RIT1,ILK,CDKL2,NSA2,FTSJ3,MYC,SCN3B,LRIF1,ESR2,RPL19,APEX1,RPL7L1,RPL35,LMBR1L |
| 5.004e-05 | -9.90 | PAM16 (presequence translocase associated motor 16) | protein interactions | 51025 | 117 | 53 | 19454 | 5460 |
PHB1,FEZ1,SSBP1,HRAS,GATD3,FZR1,HNRNPL,ATG9A,MTRF1,TMEM70,RHOG,TMOD2,MRPS26,NDUFA4,BLOC1S2,MRFAP1,HINT2,FASTKD5,NDUFA2,MTCH2,FAM13B,MRPL11,METTL15,AQP3,CCDC90B,TACO1,PTPMT1,ACTB,TMOD3,RANBP6,PARL,VIRMA,PMPCA,MYC,AUH,TUFM,CEP70,ATP5F1A,DNAJC19,TSPAN15,EXD2,ATP5MK,MME,MAIP1,GFM1,SLC25A51,GPM6A,TIMM17A,HSPA5,PGRMC1,NPY2R,ATP5PO,MTRES1 |
| 5.004e-05 | -9.90 | CHORDC1 (cysteine and histidine rich domain containing 1) | protein interactions | 26973 | 117 | 53 | 19454 | 5460 |
SNRNP27,UBE2M,RPA2,LMNA,TCEA1,HSPA8,RPA3,SSR3,SUB1,UBE2H,SORD,HSP90AA1,CYP1A1,BICD2,SPOP,CHORDC1,ABHD14B,TUBA1B,DLST,BCCIP,PPP5C,TCAP,MSX2,GTF2E2,UBE2V1,TP53,KBTBD4,SH3GLB1,CAPN2,CHMP4C,GPX7,CDK5,SEPTIN7,DDR1,SCYL2,TTC4,CSE1L,G3BP1,KRAS,KDM4B,DDRGK1,XPO1,DPY30,CDC37L1,DRG1,YWHAB,AHSA1,FKBP4,CDCA3,XPO5,PRCC,HSP90AB1,RPL35A |
| 5.006e-05 | -9.90 | NOA1 (nitric oxide associated 1) | protein interactions | 84273 | 106 | 49 | 19454 | 5460 |
DCTPP1,MRPS17,MRPS18C,MEPCE,IMMP2L,HINT2,MRPS18B,COX8A,MRPS11,PDHA1,PNMA2,AURKAIP1,MAP1LC3B,MRPL11,MRPS23,SURF6,SPPL3,TRMT10B,GATD3,BOK,SSBP1,AIFM1,MRPS9,SRSF1,MRPS26,RHOG,SNRNP70,KLHL22,TRA2A,MTRF1,HSCB,RBM22,HSPA8,EXD2,ZNF574,MTRES1,MRPS34,APOBEC3C,RBMS2,RPL27A,RPL10,RPL19,ARF1,MCAT,MRPS25,H2BC9,CSK,AUH,GRB10 |
| 5.010e-05 | -9.90 | EIF3H (eukaryotic translation initiation factor 3 subunit H) | protein interactions | 8667 | 268 | 105 | 19454 | 5460 |
USP3,ENY2,EDC3,GTF2E1,CSNK2A1,CD81,COPS5,CDK12,AIFM1,TOP1,RPS16,RBM42,TP53,YTHDF2,RRM1,EEF1A1,DISC1,TAF2,SRP72,MRPS18B,ABCE1,CPNE2,EIF4EBP2,EIF3E,RIGI,MEPCE,MED22,TUFM,EIF3G,UBE2H,PTTG1,PDCD4,TUBA1B,CTTN,METAP2,CCNF,PSPC1,RPS20,CSNK2B,UBA3,VIRMA,SMURF1,SPTBN1,ATG16L1,EIF3J,GABRA1,RPA2,LUC7L3,HEXIM1,UBE2M,SOD1,RPA3,BAP1,MAVS,RPL4,EIF4E,RPL6,WWP2,EIF3D,HNRNPA1,XPO1,DRG1,MGMT,TCP1,SNRPD3,LYAR,HNRNPL,HSP90AB1,HMG20A,EZH2,SKA3,SART3,GPBP1L1,RPS11,SCYL2,G3BP1,PAEP,COPS4,SSRP1,PSMD12,SFN,MYC,CCDC85B,BRCA1,LMNB1,FAS,ICAM1,HSP90AA1,EIF3K,RPS9,PRMT5,ACTB,EIF4A2,ESR2,EMC9,EIF4B,PEBP1,EP300,RAB5A,TMEM203,EMG1,STAU1,EIF1B,TRA2B,G3BP2 |
| 5.026e-05 | -9.90 | NUP214 (nucleoporin 214) | protein interactions | 8021 | 165 | 70 | 19454 | 5460 |
NUP35,CDK9,SUMO2,XPO5,TSG101,ETV6,SMAD3,NXT2,SMAD4,CTNNB1,XPO1,IFI16,IMMP2L,NUP42,NUP107,G3BP1,KRAS,HAPSTR1,NUPR1,ACOT13,GLE1,TUBB4B,EZH2,SMAD1,NUP153,EEF1A1,SOX2,RANBP1,E2F4,TOP3B,DYRK1A,VIRMA,ESR2,RPL19,TAX1BP1,FBXO22,PHF21A,UBE2I,RAN,LMBR1L,S100A6,CCNF,MAPRE1,RIT1,UHMK1,XPOT,SMAD2,BRCA1,CHORDC1,CFL1,CUL2,CUL3,MYC,EMILIN1,G3BP2,CSRP1,FXR2,KDM1A,RNF113A,HDAC5,SIRT7,DVL2,RPA3,ACACA,VPS4B,RPA2,LMNA,NEK7,NUP62,SYK |
| 5.034e-05 | -9.90 | nucleoside triphosphate biosynthetic process | biological process | GO:0009142 | 99 | 48 | 18204 | 5365 |
UCK2,COX11,ATP5MK,NDUFA12,NME2,NDUFA5,NDUFB7,ATP5MC3,NDUFA1,NDUFS8,NDUFB10,ATP5F1A,NME1,NDUFAB1,NUDT2,ATP5PD,NDUFB6,NDUFV2,ATP5F1B,UCKL1,NDUFS2,ADK,ATP5MG,ATP5PB,UQCC3,STOML2,DNAJC30,DTYMK,NDUFA2,NDUFB8,ATP5PO,LIPA,SDHB,NDUFS6,NDUFC2,ATP5PF,SDHC,AK3,TYMS,ATP5F1E,NDUFS3,NDUFB5,ATP5MC1,ATP5F1D,NME4,UCK1,ATP6V1A,NDUFB4 |
| 5.069e-05 | -9.89 | ubiquitin conjugating enzyme complex | cellular component | GO:0031371 | 8 | 8 | 19108 | 5553 |
RNF20,UBE2V1,STUB1,UBE2N,UBE2B,UBE2A,UBE2V2,RNF40 |
| 5.077e-05 | -9.89 | TRMT1L (tRNA methyltransferase 1 like) | protein interactions | 81627 | 194 | 80 | 19454 | 5460 |
FEM1A,RPA2,APOBEC3C,LMNA,MACROH2A2,HEXIM1,RPL26L1,BET1,RPL27A,SYK,NTPCR,POLR1D,GABRA1,RPL4,ZNF692,GTF2I,UFL1,MIR106A,G3BP2,NOG,NLE1,BAP1,RPA3,TCEA1,RAB9A,EP300,RNF113A,RC3H2,MECP2,THTPA,CUL3,MYC,UFD1,SNRNP40,RPL13A,TAX1BP1,RPL10,RPL19,PSPC1,CCNF,POLR3H,POLR2F,POLR3B,FGFBP1,EZH2,MIR17,SRP72,PPP4C,GBE1,RPL15,AURKAIP1,SOX2,HNRNPK,VRK1,RPL28,RPS13,MEPCE,EIF1AD,RPL31,HSPD1,RPL23A,RPL3,SNRNP70,MIR34A,DRG1,PLEKHO1,WWP2,IFI16,DDRGK1,MAP3K14,POLR3GL,COPS5,SUMO2,FZR1,POLR3F,RPS16,CAND1,CDC5L,RBM42,MIR141 |
| 5.077e-05 | -9.89 | PDCD6 (programmed cell death 6) | protein interactions | 10016 | 194 | 80 | 19454 | 5460 |
CCNF,VIRMA,ESR2,CLIC4,DAPK1,TXN,SMARCE1,BAG3,MYC,CSK,CCNB1,CUL3,CUL2,SEC13,GFUS,UBE2H,PRR19,ADK,FAS,HNRNPH2,MIA2,SQSTM1,ARFIP1,RPA3,CSTB,HDAC3,NF2,CNPY3,CFTR,CCNA2,TPT1,HNRNPH3,HAUS2,PIH1D1,AKR1A1,ANXA7,RPA2,LMNA,IGBP1,TSG101,TYMS,SEC23A,LMAN1,CPNE1,CAND1,KCTD15,RAB1B,MIF,HDAC6,XPO1,MOV10,NFKB1,HEBP2,WWP2,DDX1,MED4,TSNAX,MAP4,DROSHA,CPNE2,MAP1B,PABPC1,DUSP21,TFG,SAR1B,RIGI,SEPHS1,IMPA2,MAPK1IP1L,TOLLIP,TRIM37,H2AX,ERLIN2,RAF1,FASLG,TP53,SMARCB1,CRKL,KLHL12,CHMP4C |
| 5.088e-05 | -9.89 | AXL (AXL receptor tyrosine kinase) | protein interactions | 558 | 347 | 131 | 19454 | 5460 |
MRPS25,CHTOP,YWHAZ,SERPINH1,NSA2,HSP90AA1,PIK3R3,RPL39,RPL7L1,SEC61B,VAPB,PAFAH1B1,USP6NL,ETF1,SLC31A1,G3BP2,MRPS7,PYGB,ARRDC3,HADHA,HSPA8,YWHAB,CBL,UBXN6,BAZ1B,PDIA3,PIK3R1,SHC3,SNX1,EIF2S1,HSP90AB1,PPIA,RAMP3,SWAP70,MRTO4,RPLP1,TMEM204,RPN1,PLD3,STBD1,ERRFI1,RUVBL1,RAD21,RPS27A,NDUFA4,PABPC1,PPAN,ERP29,BAG2,EFNB1,DNAJC10,SDF2L1,CALU,EPHA2,XPOT,OAT,CIAO1,PTPN11,RPF2,SLC25A1,SMARCA5,ZNF622,VIRMA,SRC,CYP4F12,SEC63,CIB2,CTTN,GAB1,STUB1,SGTA,MACROH2A1,SLC1A1,SEC61A1,GANAB,EIF2S2,WWP1,HSP90B1,MRPS34,JUP,RARS1,EEF1E1,CFTR,CNP,MRPL10,LPAR1,PIK3R2,MRPL17,TICAM2,IRF3,MYH2,SEPTIN6,TEX264,MTDH,ITGA2,RTN4,ESYT1,SHC1,SLC2A1,TUBG1,KARS1,CALR,LRRC40,COPS5,ARF6,SURF6,ILVBL,LMAN1,TMPO,UBE2N,EEF1AKMT3,MRPS9,SRPRA,ARL4D,CDCA3,SEC23A,ACVR1,NHERF1,GNAI3,BIRC5,DDX39A,TGFBR2,TMEM33,HNRNPK,SRPRB,AKAP12,PRDX4,ARF4,FBXO25,DLG1,ERO1A |
| 5.097e-05 | -9.88 | t_SNARE | smart domains | SM00397 | 22 | 15 | 9717 | 2575 |
VTI1B,STX5,STX7,STX10,BET1,STX17,STX11,SNAP25,STX6,SNAP29,STX16,SNAP23,STX1A,STX8,STX12 |
| 5.108e-05 | -9.88 | ENO2 (enolase 2) | protein interactions | 2026 | 131 | 58 | 19454 | 5460 |
FKBP1B,NTRK3,BMERB1,OAT,CHCHD4,GMPS,PPP1CC,EXOC5,CUL3,TXNRD2,CUL2,AKT1,ST3GAL2,PNP,TAGLN2,TXN,PTEN,MSN,EFHD2,ENO1,ACOX1,FKBP1A,HEXIM1,PPT1,OXCT1,UCHL3,GPX4,PGK1,SOD1,BAP1,MAP4,NME2,GAPDH,PPIB,PGAM1,CALR,SUMO2,SUMO3,CAND1,AKR1B1,FABP5,NGB,EZH2,PLS3,TFCP2,EEF1A1,TPD52,NAT9,RIGI,FKBP2,HSPE1,TF,UBE3A,IDH1,TAGLN3,HSD17B10,HINT1,RAB1A |
| 5.108e-05 | -9.88 | MRPL51 (mitochondrial ribosomal protein L51) | protein interactions | 51258 | 131 | 58 | 19454 | 5460 |
MRPL33,RPL18,MRPL49,MRPL11,MRPL47,KRAS,SRSF4,MRPL22,RPL17,MRPL52,RPL3,SRSF7,RHOG,MRPL18,SNRNP70,MTRF1,RPL6,MRPL9,MRPL50,MALSU1,MRPL24,ALYREF,PRR3,LDLR,MRPS18A,FEM1A,MTRES1,RPL27A,MPV17,MRPL10,MRPL12,RBMS2,TMEM177,MRPL17,HSCB,MRPL40,MRPL41,MRPL57,MRPL20,FTL,NGRN,GFM1,PSMG3,MCAT,AUH,MYC,RPL26,MRPL16,TUFM,MRPL23,LAMTOR3,RPL13A,RPL19,MRPL53,TACO1,MTG1,RPS9,MRPL13 |
| 5.109e-05 | -9.88 | Innate Immune System | REACTOME pathways | R-HSA-168249 | 1285 | 465 | 10285 | 3229 |
MBL2,IRF7,SURF4,GLIPR1,CD59,STAT6,PAFAH1B2,CCR2,NCKAP1,AKT1,PIK3CA,HSP90AA1,PSMD1,CNPY3,MAP2K6,BCL10,TAB2,DEFB116,CGAS,CUL3,CTSD,PSMA1,SIKE1,CTSK,RASGRP3,TUBB4B,STOM,BCL2L1,SERPINB10,MET,NFKB1,IRAK4,HUWE1,PAQR3,IFI16,PIP5K1A,TANK,IL2RG,DNASE1L1,PIK3R2,HSP90AB1,ELK1,DUSP6,KRAS,NPC2,TNRC6C,MAVS,FGF22,TLR10,VAMP8,FGR,CD36,CAPZA1,DEFB115,HMOX2,PLPP4,FTH1,TLR1,LGALS3,ICAM3,DHX9,SHC3,CCT8,PRKCE,XRCC5,RNASET2,TLR3,CSF2,CAND1,BST2,JAK1,IL1B,CD63,MAP3K11,BAD,GOLGA7,JUP,UBE2M,BIRC2,MYH2,IL2RA,AGER,FGFR1,PSMA4,PSMB6,PSMA2,TMT1A,ADCY2,CD3G,TNFRSF1B,PSMB1,AHCYL1,PSMC4,VAV2,RAB27A,PTPN11,PSMD14,POLR2F,LCP2,PELI1,SERPINA1,POLR3H,POLR2L,ELMO1,BPIFA2,ANGPT1,PDE1B,SPTBN1,PTPN4,SERPINB6,MAP2K3,TNFAIP6,PIP4K2C,KIT,IL5,ATP6V1G2,UBE2K,RAB9B,DEFB1,CAMK2G,TXNIP,PDAP1,POLR3GL,FGF16,MAP3K14,RAP2C,HP,CAPN1,UBE2N,VWF,IFNA10,PRDX4,CD86,UBE2D3,TP53,COTL1,PRCP,PLD3,APEH,CFL1,RPS27A,POLR3B,RAB6A,DUSP3,CLEC7A,NLRP3,GCA,CST3,DUSP1,PGM1,KLRC2,B4GALT1,RIGI,SYNGR1,ATP6V1D,CASP4,IFNA2,PSMA5,FCER1G,PSMB3,PEBP1,CD247,YES1,ATP6V1C1,TLR9,ICOS,SNAP25,FABP5,TLR6,SLPI,YWHAB,CDC42,CTSB,ARMC8,PNP,PI3,PADI2,SRC,DUSP9,TMEM30A,FRS3,TBK1,NFKBIA,PPIA,SRP14,TLR7,RAB5C,EEF1A1,TICAM1,TOM1,ENPP4,MME,FCAR,PIK3R3,MAPKAPK3,CD4,NFKBIB,CTSA,ATF1,CAB39,MAPK10,CXCR1,NLRP1,PPP3CA,NEFL,DUSP10,RAB31,PSME2,IFNB1,MYD88,HSP90B1,SPRED2,JUN,TYROBP,IL2,OLR1,B2M,C1QC,DNM2,S100A8,CD28,DLG4,BRAP,CSK,CTSC,FBXW11,ITK,TRIM32,PIK3R1,LILRA3,CREB1,LAMP2,IRF2,CDKN1B,TMBIM1,TLR4,HSPA8,PRKCA,WASF3,DEFB121,AGO1,PPP5C,NCSTN,ATP6V1E2,BRI3,FGL2,FGF17,CD80,ELMO2,BPIFB4,UBE2V1,YPEL5,PRDX6,HRAS,PPP2CB,AGA,ACTR1B,PEA15,PSMB2,TUBB,LAMTOR3,CREBBP,SLC2A3,PSMC1,TMEM179B,ARPC2,CTNNB1,PSMD4,PHB1,CSTB,ITGAV,IL3,PAK2,IDH1,LYZ,IKBKB,SHC1,TLR2,TBC1D10C,ACTR2,LAT2,PTEN,SERPINA3,SPTAN1,STBD1,TRIM21,CYSTM1,SELL,FGF1,ACTB,FCGR2A,PROS1,TAB1,ISG15,LEAP2,PLEKHO2,MAP2K1,CD58,RAB14,PELI3,RAF1,NDUFC2,ATP6V0E1,SYK,SDCBP,NME2,IRF1,CAPZA2,PSMD10,SVIP,MMP9,ROCK1,MOV10,AKT2,CLU,CHGA,DEFB114,PYCARD,FTL,TRAPPC1,WASL,PSMD12,BPIFB1,TNFAIP3,IRF3,FCGR1A,POLR3F,DYNLL1,GRAP2,GSK3A,FAF2,ATP8A1,SARM1,TRAF6,FGF3,PSMB9,PSMB11,LY96,TLR5,KLRD1,NCKIPSD,CSNK2B,SNAP23,MIF,JAK2,COMMD9,CD46,RAP2B,CAMP,PSEN1,MEF2C,UBB,PPP2R1A,CALML5,PSME1,HBB,ATP6V1G1,ILF2,POLR1D,NCK1,SNAP29,CYFIP2,PYGB,GAB1,LAMTOR2,CCR6,CHI3L1,RNASE6,AKT3,PSMA6,IL2RB,IER3,GDI2,ARPC3,EEF2,TRAF2,TOLLIP,PSMC3,SPRED1,HMGB1,PSMB4,ATP6V1A,TICAM2,RAB18,CD14,SEM1,CPNE1,CCT2,FGF23,TLR8,CLEC6A,PDE1A,PPP2R5E,DEFB124,RAB3A,IFNA13,S100B,RHOG,PPP2R5A,MDM2,CYB5R3,PRKCQ,RAP1B,ATG7,RASGRP2,UBA52,CD209,WDR83,COMMD3,EP300,FGF10,PIK3AP1,HEXB,RAB3D,TAX1BP1,CMTM6,RAP1A,MEF2A,CDKN1A,DEFB129,TIRAP,FGF7,PGAM1,ATP6V0B,ICAM2,LAMTOR1,RETN,CD47,NEU1,HEBP2,PSMD6,DNAJC5,GGH,HBEGF,RAB37,SIGLEC5,UBE2D1,FCN2,S100A11,TXN,ORMDL3,PSMC5,PSMB10,DEGS1,GSTP1,PSMD3,DNAJC3,PSMB7,PLAC8,PSMB5,PSMA3,CXCL1,FOS,TTR,ADCY3,PGRMC1,AP1M1,PRKACB,SKP1,IFIH1,UBA3,DSN1,ATP6AP2,PSMD7,SERPINB1 |
| 5.138e-05 | -9.88 | INSR (insulin receptor) | protein interactions | 3643 | 344 | 130 | 19454 | 5460 |
KRAS,PDIA6,JAK1,NDUFA4,HGS,CRKL,RPN1,STIM1,RAF1,OS9,WDR44,SNX2,SNX1,HNRNPL,OCRL,COCH,STX5,SNX17,GJA1,WDR6,PTK7,YWHAB,CBL,HAX1,CDK5RAP3,DDRGK1,QPCTL,PSMD3,PIK3R1,HMGA1,RNF41,ITGAV,ADRB2,GOSR1,EMC1,DNAJC3,ARCN1,SLC25A3,FKBP10,VAPB,CHP1,JAK2,MAD2L1,ARF1,DOK4,SERPINH1,SCFD1,RHOB,LAMTOR1,GGH,CAV3,GRB10,SFN,PIK3R3,CUL3,VEZT,NIBAN2,DUSP19,SOCS2,SRPRB,HSPE1,EMC2,IGF1R,SELENOF,ADAMTS1,SOCS3,LY6H,CCDC47,PLA2G5,DOK5,CAV1,CDCA3,HSD11B1,SEC23A,TRAPPC3,EHBP1,SRPRA,HACD3,HRAS,SYNCRIP,PTPN1,OSBPL8,SHC1,ESYT1,SCGB1D1,FCGR2B,EMC4,DPP4,TMEM209,FABP4,HSPA5,CHMP2B,PIK3R2,GPIHBP1,YKT6,IRF7,SQSTM1,MTDH,INPPL1,LEMD3,PRKCA,MET,HSP90B1,NTPCR,TMEM106A,ARHGAP1,SPR,RABL3,DUSP18,AKR7A2,SRC,SEC63,VIRMA,TECR,STAT5A,COPE,GANAB,DNASE1L1,SEC61A1,STUB1,GXYLT1,GAB1,SNX5,OAT,EPHA2,SMAD2,DNAJC10,SDF2L1,PTPN11,CSK |
| 5.159e-05 | -9.87 | regulation of kinase activity | biological process | GO:0043549 | 531 | 198 | 18204 | 5365 |
CD86,PPIA,GNAQ,HSPB1,PRDX3,DUSP19,ERP29,FERMT2,RTRAF,TOM1L1,IGF1R,TLR3,EPHA4,FGR,LDB2,IL12B,CCL5,YWHAG,CDK5R1,SPRY1,SOCS4,PRNP,EEF1A1,MAP3K12,HSP90AA1,INPP5K,ERRFI1,TPD52L1,PSRC1,PRKAG1,CAV3,CDKN2D,AGAP2,HSP90AB1,TAB1,DSTYK,CAV1,MIR21,CD4,LILRB4,SFN,CDKN3,LCP2,SMG8,PPP2R5A,RGCC,IL4,PKIG,EMP2,SOCS5,MT3,CCNI,CCND3,GH1,TXN,HYAL2,GSTP1,MAP2K3,DUSP3,CHP1,TGFB2,IGF1,DBNDD1,PDCD10,SPRED1,PROX1,ADRB2,TLR6,CCR7,AKT1,TNFSF15,IL1B,RAP2B,PTPN22,DEFB114,FCGR1A,BAD,DIRAS3,DVL2,CDK5RAP3,MAP2K1,HGS,FGF1,PKIB,LRP6,MACROH2A1,PTEN,JAK2,MMD,TSG101,DIRAS2,CARTPT,SOD1,SLC8A1,DLG3,CCND1,CDK12,PAK2,TGFBR2,KIT,CBL,MIR20A,MET,LMO4,MIR34A,MIR15A,PDCD4,CACUL1,TAB2,TCIM,IFNG,CCNY,TAF7,DIPK2A,PIK3CG,THY1,TLR4,DLG4,LEP,TRIM27,HEXIM1,PHB2,PTPN1,GHR,SRC,RAP2C,ANGPT1,FGFR1,PTPRQ,MIR26B,CEP85,UBASH3B,EZH2,IL23A,IL34,CCNA2,CCNB1,NBN,PAQR3,CAMK1,MIR218-1,NTRK3,PPARG,NTRK2,MIR711,CDKN1B,SERTAD1,DUSP1,PHB1,RPS3,CDKN2C,RAP1A,TRAF2,MIR24-1,DUSP22,ACTB,CAMK2N1,MAP3K11,ADIPOQ,TNF,STK11,PKIA,PYCARD,HRAS,STK38,DUSP10,FBXW7,BCCIP,CAB39,EPHA2,RALB,HEXIM2,RGS2,CD40,CORO1C,FGF16,RB1,STRADB,TESK1,PIH1D1,CDKN1A,ZNF622,PSMD10,NHERF1,CHI3L1,TRIB1,XRCC5,CCL19,DIRAS1,F2,CAMK2N2,CCNF,GADD45A,TRAF6,LDB1,GSKIP,CCNH,DDR1 |
| 5.164e-05 | -9.87 | TMEM237 (transmembrane protein 237) | protein interactions | 65062 | 197 | 81 | 19454 | 5460 |
ADIPOQ,EMC8,KRAS,TMEM60,LEPROTL1,RUSF1,LTA,STX8,TMEM147,EMC2,CTSA,BPIFB1,SRP72,CYB5B,JCHAIN,INSIG2,MACO1,CCDC47,RAF1,IFNGR1,MFSD6,RHOH,CXCL9,PRNP,ARF6,TLCD4,SLC38A2,HRAS,SRPRA,RPRM,RAC2,MFSD5,TMEM42,FXYD6,TMEM11,RHOG,BTN2A2,SLC38A7,TMEM144,ORMDL3,SLC41A1,TMEM107,EMC6,CMTM6,SLC7A1,EMC1,LRP10,SLC39A9,JAGN1,RHOU,MTDH,TMEM254,FKBP14,GRM2,BET1,CLDN4,BLCAP,CFTR,SEC22A,CCDC167,CDC42,RHOJ,EFNA5,METAP2,VAMP3,VEGFA,RETREG3,RHOB,LGALS8,SLC35E4,TMEM179B,SP1,GJB2,TM4SF19,MAT2A,RAB2A,DNAJC5,SLC35B4,MTPN,FBXO7,SLC16A4 |
| 5.174e-05 | -9.87 | NUP133 (nucleoporin 133) | protein interactions | 55746 | 168 | 71 | 19454 | 5460 |
NUP153,ACTR1A,NUP37,RAF1,COMTD1,RANBP1,CDK4,TP53,E2F4,NUPR1,SKA3,GLE1,VPS33A,STIM1,HDAC11,CHMP4C,COX8A,POLE4,UBE2A,FKBP8,G3BP1,NUP107,KRAS,CSNK2A1,XPO1,IFI16,DDX1,EED,COQ8A,PTPN1,RCHY1,EGLN3,TMPO,CETN2,NUP35,DNAJC1,SEC62,NUP62,SF3A1,RPL26L1,LMNA,DERL1,NUP50,RPA3,SIRT7,TOMM20,B9D2,DUSP26,BTF3,NONO,MYC,SEC13,RAB11A,CUL3,XPOT,MAPRE1,LMNB1,BRCA1,BICD2,ZMYM2,FOXP3,GSK3A,SEC61B,PTPMT1,LMBR1L,CCNF,RAN,ESR2,VIRMA,TCAP,RPGRIP1L |
| 5.212e-05 | -9.86 | CBARP (CACN subunit beta associated regulatory protein) | protein interactions | 255057 | 74 | 37 | 19454 | 5460 |
SHOC2,RND3,SLC35F6,CDC42,RND2,KRAS,FLOT1,STX7,SLC39A9,RHOU,RAB9A,NTRK2,FBXW11,YWHAZ,RHOB,RHOG,STYK1,YWHAB,SFN,PPP1CC,DNAJC5,YWHAG,YWHAH,RHOJ,RHOH,CD151,CAV1,STX6,DIRAS3,TRAF3IP3,HRAS,RAB35,UBASH3B,RAC2,CACNB3,MFSD5,GJA1 |
| 5.212e-05 | -9.86 | ARL3 (ADP ribosylation factor like GTPase 3) | protein interactions | 403 | 74 | 37 | 19454 | 5460 |
YWHAB,UBE2H,TRAPPC4,YWHAZ,ARL2BP,LAMTOR1,YWHAG,LAMP3,YWHAH,TLE1,ALKBH2,LAMP2,RAB2A,SURF6,LRIF1,PRNP,ARF6,PDE6D,TRAPPC13,CRABP2,CFAP36,ACTR2,CTDSP2,TUBA1A,TP53,RBM12,IMPA2,DNAAF9,SLC37A4,UNC119B,CSRP1,RP2,ARPC2,AKAP1,ATP5IF1,HSPA8,TMEM263 |
| 5.212e-05 | -9.86 | KCNK1 (potassium two pore domain channel subfamily K member 1) | protein interactions | 3775 | 74 | 37 | 19454 | 5460 |
EI24,SYNJ2BP,CREB3,TMED4,TM9SF4,CBL,RMDN3,UBE2I,ACSL4,CDIPT,SRPRA,MPDU1,EXTL2,VKORC1L1,SEC63,ACP2,ARL6IP5,DERL2,SLC25A4,YIPF3,TMEM126A,COQ8B,LEMD3,DHRS7B,TMEM14B,LMNA,HSPA13,STOM,SIGMAR1,TMEM87A,ATP2C1,TMED1,LPCAT3,RAB18,PGAP4,CMTM6,RER1 |
| 5.212e-05 | -9.86 | TBC1D9B (TBC1 domain family member 9B) | protein interactions | 23061 | 74 | 37 | 19454 | 5460 |
LAMP2,CUL3,GPR17,TAFAZZIN,TYROBP,LMBR1L,S1PR4,EEF1AKMT3,MAP1LC3A,FAM43A,TMEM108,ARL4D,SPINT2,ILVBL,ABHD12,VIRMA,LANCL1,TOP3B,COMTD1,MAP1LC3B,FAXC,GABARAPL1,SEC62,CLEC2B,CFTR,GABARAPL2,VAPB,RPA2,SIGLECL1,AQP3,ADORA3,RPA3,EFNB1,RAB9A,HSCB,SEMA4C,PIP4P1 |
| 5.212e-05 | -9.86 | IRF1 (interferon regulatory factor 1) | protein interactions | 3659 | 74 | 37 | 19454 | 5460 |
FLOT1,SS18,H3C1,FBXW7,DR1,UBE3A,EP300,SMARCD3,E2F6,POLR2D,IRF8,MED23,NFE2L2,DDX39A,MDM2,SEC63,STAT1,CSNK2B,GTF2F1,IRF2,SP2,STUB1,CBL,HSP90AA1,CDKN1B,SPOP,TRAF6,BCL7C,CSNK2A1,DRAP1,NFKB1,HMGA1,CREBBP,IRF9,ERCC3,SUB1,XAF1 |
| 5.270e-05 | -9.85 | Interleukin-10 signaling | REACTOME pathways | R-HSA-6783783 | 49 | 29 | 10285 | 3229 |
IL1A,ICAM1,IL4,CCR2,CCL20,CXCL1,CCL5,JAK1,CCR1,IL6,CCR5,IL18,CCL2,CSF2,CCL19,IL12A,TNFRSF1B,CXCL8,TNF,IL1R2,TIMP1,CD86,IL1B,IL10,IL12B,CD80,CXCL10,CCL3,IL13 |
| 5.270e-05 | -9.85 | MED27 (mediator complex subunit 27) | protein interactions | 9442 | 98 | 46 | 19454 | 5460 |
MED11,FBXW7,RPA3,MED13L,RPA2,MED23,MACROH2A2,MED31,ATG16L1,FBXL19,MED30,MED17,POLR2B,CPSF1,CCNF,POLR2F,MACROH2A1,MED10,STN1,RIT1,MYC,MED22,FBXO7,AR,TRIP4,TOP2B,CDK8,POLR2C,POLR2G,POLR2D,RBPJ,ARFGAP1,RAF1,H2AJ,MED9,RPAP2,HNRNPL,POLR2I,H2AZ1,POLR2L,MED21,MED29,MED4,H2AC14,MARCHF5,ZCCHC10 |
| 5.283e-05 | -9.85 | DCTN2 (dynactin subunit 2) | protein interactions | 10540 | 335 | 127 | 19454 | 5460 |
TNIK,PHB1,RPLP1,DYNC1I2,SNRPA1,UQCRH,CNTROB,EGLN3,CCDC172,NUF2,HSP90AB1,IFI16,DDX23,MED4,RINT1,GADD45A,BLOC1S2,ACTR1B,TRIM11,PSMA2,KRAS,PSMA1,RUVBL1,PSMD12,MCM6,CCAR1,TRMT1L,MARCKSL1,SPC24,ARFGEF1,SOX2,PPP2R1A,TUBB4B,SKA3,CHMP4C,MTA2,POLR2D,MOB3C,HGS,PRMT5,MATR3,PSMD4,RBBP4,DYNLL1,TENT5C,ACTB,GADD45G,PSMB6,MYC,CUL3,RAB11A,PSMD1,MCM4,CKB,LMNB1,MYO6,PEBP1,UPF3B,EXD2,EP300,DCTN3,PSMA3,HSCB,FXR2,PSMC1,TOMM22,PAFAH1B1,BORCS6,ELOVL1,COQ8A,EHBP1,ARMC1,VTI1B,RPS16,FZR1,PRNP,CDC5L,MED29,USP15,FAF1,HAPSTR1,CTNNBL1,PSMA5,DYNC1I1,KPNA2,MEPCE,CAPZA1,DUSP19,TBK1,KBTBD4,TP53,ACTR1A,IFT57,DISC1,CAPZA2,DNAJC2,RNF181,TSSK1B,CCNF,GNAO1,PSMC5,SMURF1,VIRMA,DYRK1A,EMILIN1,DNAJC8,BICD2,CCDC22,UBE2H,MAPRE1,RPA3,BAP1,PML,DCTN6,EXOSC4,SMC4,AKR7A2,PSMC4,CFTR,RPA2,DCTN4,COX6C,HEXIM1,ZNF574,UBE2M,SCLT1,HECTD1 |
| 5.317e-05 | -9.84 | ARHGAP21 (Rho GTPase activating protein 21) | protein interactions | 57584 | 171 | 72 | 19454 | 5460 |
RND3,SAPCD1,PNMA2,NECAP1,CAPZA2,DDX42,TULP3,SOX2,TOP3B,CSNK1E,FLOT1,CTNND1,KRAS,BAG2,ZYX,S100B,YWHAB,NCK1,RHOG,CTNNB1,YWHAH,PPIL4,XPO1,YWHAG,LANCL1,SLC25A12,CAV1,DIRAS3,EGLN3,STX6,VPS26C,ARF6,PLG,KRT8,RAC2,GJA1,RAB35,HRAS,TRIM36,TMOD1,PPP1CB,CDC42,STX7,HSCB,KDM1A,ATP5IF1,ZNF177,UBE2H,MAPRE1,SP1,RHOB,BRCA1,LMNB1,YWHAZ,PPP1CC,SFN,PKP4,RAB2A,MAT2A,VIRMA,MAT2B,PPP1R10,FBXO22,ACTB,RHOJ,MSN,PHF21A,GSK3A,FBLN5,CTNNA1,ARF1,PSPC1 |
| 5.317e-05 | -9.84 | PRKACB (protein kinase cAMP-activated catalytic subunit beta) | protein interactions | 5567 | 171 | 72 | 19454 | 5460 |
CSNK2A1,XPO1,HP,PKIA,CBL,AKAP8L,PKIB,DDX23,SPP1,TRAF6,RAC2,NHEJ1,NAA11,HSP90AB1,HNRNPL,TOP1,DDX39A,ARFGAP1,ETFB,POLR2C,CSTPP1,H2BC1,ACTR2,AKAP14,RABGGTB,PICK1,DHX9,PALM2AKAP2,PFDN1,TF,ACVR1B,FBXO7,H2BC9,NONO,MLF1,HSP90AA1,MAPRE1,CDKN2AIP,H2AZ2,AP2M1,GSK3A,BAD,DCLRE1C,ARF1,AVPI1,RAN,POLR2B,DYRK1A,RAPGEF5,MATR3,DYNLL1,BMP1,MYH1,RPE,RPL27A,PKIG,SUMO1,TFIP11,VAPB,LMNA,H2AC1,APPBP2,MAVS,DDX5,ARPC2,KLHL28,AKAP1,TIMP3,XRCC5,MYH2,NAPG,NOP53 |
| 5.319e-05 | -9.84 | H1-4 (H1.4 linker histone, cluster member) | protein interactions | 3008 | 509 | 183 | 19454 | 5460 |
PML,DERL1,RNF113A,EXOSC4,RPS15,SDCBP,RPA2,ZNF770,TFB1M,PRKCA,HEXIM1,RPS3,MACROH2A1,RBMX2,PHAX,PYGM,RSL24D1,SRPK2,RPL7A,SMARCA5,RPF2,H2BC9,RPS17,RC3H2,BICD2,CDKN2AIP,ELAVL2,TRAFD1,RPL3,IMP4,H3C1,RPL17,MEPCE,IMP3,RBM34,CBX3,NUPR1,PREP,SPPL3,RPS16,SURF6,TMPO,DKC1,CMSS1,TCEANC2,CD81,RPL10A,RPS2,NOL12,SLU7,HSPA8,SF3B1,STAU1,UFL1,CRYBB3,SNRNP40,CBX5,HNRNPC,MYC,BTF3,PSMD14,FTSJ3,CCT2,NSA2,COP1,ICAM1,TOP2B,RPL31,H1-6,RPS4X,MSX2,H1-3,GLE1,TPPP,RPL18,SRSF1,SNRPA1,RPS10,ISG20L2,RPL6,DDX50,IFI16,BAZ1B,MRPL9,AGR2,SIRT7,HELLS,RPA3,PRKCB,RPL4,FBXW7,BRIX1,AATF,UTP23,PIAS1,UBA52,RBFOX2,CDK7,RBMS2,GRM2,FBP2,ZNF574,RPL26L1,RPLP0,EIF2AK2,UBASH3B,RPS20,PRKRA,RPL13A,VIRMA,TUFM,USP14,RPL26,NKRF,ZC3H11A,RPL23A,FRMD8,NOC4L,TOM1,VRK1,PAK1IP1,RIGI,MRPL22,RPS13,RPL15,FCF1,MAP1LC3B,SRP72,KRR1,ARL10,RPL12,TES,MYBL2,NOP9,ZBTB2,MRPS23,CDK9,SPATS2L,MOV10,NFKB1,GRSF1,MPHOSPH10,DNAJC7,YTHDF1,NOP53,CCDC186,POLA2,H1-5,MFAP1,RPS9,RPL37A,RPL7L1,RPF1,NOP16,GRB10,PDE4B,ZNF668,ZCRB1,FYTTD1,RPS5,RPS24,UBE3A,IRAK4,TXNRD1,B3GNT2,MAK16,CHMP4C,PHB1,RPL9,RPLP2,RPLP1,HP1BP3,CETN2,SRSF10,VPS26A,HNRNPA1,INSYN1,ZCCHC9,WDR12,PPP3CA,BCL2L1,RSBN1L,HNRNPD |
| 5.319e-05 | -9.84 | RHOH (ras homolog family member H) | protein interactions | 399 | 509 | 183 | 19454 | 5460 |
PIK3R1,WDR11,SPTAN1,SNX2,OCRL,TMEM237,RAB11B,PPIA,ERLIN1,PHB1,WDR6,GJA1,NEO1,PCDH17,STIM1,RPN1,STX12,IFNGR1,FLOT1,PSMD12,MCM6,HSPD1,JAK1,SLC39A7,LMNB1,MYO6,SLC7A11,PKP4,NIBAN2,MRPL16,TOMM40,LRRC8A,CHCHD3,FAM91A1,AP2M1,CLDN3,VAPB,TCF19,NOTCH2,DAAM1,MTX2,ETF1,ELFN2,NSFL1C,ESYT1,POR,SLC2A1,OSBPL8,RELL1,DAG1,CAV1,DBT,EHBP1,PTPN1,HACD3,CDCA3,C2CD2,DECR2,NDUFS3,CASK,ALPL,CCDC47,CMPK1,MTARC2,CTNND1,DLG1,SFXN1,RAB1A,EHD4,SNAP23,HSD17B10,EMC2,HAPSTR1,EPHA2,XPOT,DEPDC1B,YES1,SH3BP4,IFNA10,FERMT2,TUBA1B,VAMP3,RPS12,GANAB,STOM,GOLGA5,SLC12A2,JUP,MET,MEST,SEC22B,ARHGAP1,CNP,PIK3R2,YKT6,SLC7A1,CDC42EP4,TMEM209,MAVS,WWP2,RAB5C,PTDSS1,TBC1D5,PPFIBP1,OLR1,VAMP7,SPINT2,TMEM59,SLC20A2,ROCK2,XPNPEP1,TOP2B,TMEM87A,CDK5,EFNB1,LAMTOR1,H1-1,SLC38A1,MLF2,STX16,PSMD1,LRIF1,SCNM1,RRAS2,FAM83B,UBAC2,PAK2,BET1,GOSR2,USP6NL,EMC1,PACSIN3,ABCC5,ITGAV,GNB4,NOS1AP,H2AC4,SLITRK5,KPNA1,TPM3,ARL6IP5,LMAN1,SLC38A2,STX6,TMPO,STT3A,ITGA6,FLRT2,SLC39A10,RAP1B,ADD1,BMPR2,PIK3CA,TFRC,SNAP29,CSE1L,SRPRB,NEDD8,AKAP12,FKBP8,SLC6A8,ABCE1,ATP1B3,ATP1A1,RAB2A,SLC25A1,GORASP2,H2BC9,ROCK1,ZBTB33,NECTIN2,STX10,MACROH2A1,SSR1,SDCBP,LEMD3,TFB1M,SPTBN1,CCNH,CDC42,FTSJ1,ITM2B,RAB9A |
| 5.331e-05 | -9.84 | locomotory behavior | biological process | GO:0007626 | 197 | 84 | 18204 | 5365 |
IDO1,GLRA1,EPHA4,NPY2R,KCNJ10,PPT1,PAK6,UBE3A,NTF4,FIG4,PAFAH1B1,LRRTM1,SLC6A3,GPR37,SOD2,PPP1R1B,GNAO1,CNP,HOXB8,USP2,SLC1A1,HEXA,DBH,CXCL12,LARGE1,KCND2,SLC25A46,PEX13,NEGR1,NPY1R,ELAVL4,MYG1,TBCE,ZDHHC8,EPS8,ASTN1,FGF12,DRD3,SLC4A10,SNAP25,PAK5,FKRP,CEND1,DLG4,SELENOP,GRM1,C1QL1,CRBN,KLHL1,EGR1,SOBP,HPGDS,MECP2,CIART,CLN8,NR4A2,PDE1B,PTEN,ANKH,GNG7,CHRNB2,HEXB,TUBA1A,CACNB4,PRKCE,DRD1,TNR,NLGN2,CNTN1,ABHD12,GLRB,SNCG,TMOD1,HTRA2,ZMPSTE24,SOD1,ATP1A2,ALDH1A3,OPRK1,FXN,DPP4,CSTB,FZD4,ARCN1 |
| 5.336e-05 | -9.84 | PLS1 (plastin 1) | protein interactions | 5357 | 120 | 54 | 19454 | 5460 |
MT2A,HSCB,LCP1,DVL2,CNPPD1,SCLT1,HEXIM1,FKBP14,FGFR1,ZMYM6,PRDX3,SNRNP27,ATG16L1,APEX1,BORCS7,ESR2,ACTB,MSN,NFKBIA,FKBPL,UBE2H,DNAJB6,FYTTD1,MTPN,CAPZA1,PRPS1,UBE2A,GSKIP,SLC25A32,PDIA6,INO80C,DTD1,NUPR1,FAM136A,DHRS3,CCR1,CHMP4C,PLS3,SPG21,ISG15,SOCS3,CARTPT,SOX2,SPTAN1,METTL6,CXCL14,CBL,FKBP4,DDRGK1,FCGR2A,ISYNA1,NDC80,CRHBP,GSTM3 |
| 5.374e-05 | -9.83 | TMEM199 (transmembrane protein 199) | protein interactions | 147007 | 134 | 59 | 19454 | 5460 |
CCR2,REEP4,SEC63,ATP6AP2,ESR2,ELOVL4,SEC61B,HFE,LMNB1,RIT1,RAB2A,RAB11A,STX7,PXMP2,DNAJC22,JAGN1,DERL1,RAB9A,RAB5A,TMEM185A,LMNA,SSR1,ATP6V0E1,TIMMDC1,CDC42,SEC62,OTULINL,RND2,ST7,ARF6,DNAJC1,ERLIN1,TMPO,LMAN1,RAB35,PTPN1,HSD17B11,GJA1,RHOG,ESYT1,STX1A,LAMP2,RAB5C,LAMP3,KRAS,RAB3B,FKBP8,CYP2C9,TMT1A,TSPAN17,COX8A,RPN1,STIM1,RAB4A,TMEM14B,CCDC47,CLEC2B,DDX39A,DNAJC25 |
| 5.375e-05 | -9.83 | - | gene3d domains | 2.60.200.10 | 15 | 12 | 14470 | 4137 |
IRF3,SMAD9,IRF9,SMAD5,IRF7,SMAD1,IRF4,SMAD4,SMAD3,IRF8,IRF6,SMAD2 |
| 5.395e-05 | -9.83 | CDK12 (cyclin dependent kinase 12) | protein interactions | 51755 | 206 | 84 | 19454 | 5460 |
SRSF1,ATXN10,FZR1,NUP35,CHMP2A,CDK9,EGLN3,ZCCHC10,ERCC3,BAZ1B,DDRGK1,CSNK2A1,YWHAG,SNRNP70,DDX23,ANKRD50,UQCR11,CDK12,MGMT,AKT2,EWSR1,THRAP3,CDK20,KRAS,ERLEC1,LASP1,RIGI,PCGF6,SRSF4,RPL28,H2AJ,RAF1,TOP3B,CKS1B,MAX,RPL15,PPP2R1A,ANAPC13,SOX2,CBX3,TMEM94,CDK8,TMEM14B,EZH1,RPS3,CCNF,TRIM24,PRKRA,FGFBP1,RPL37A,SNRNP40,IFI6,RPL13A,VIRMA,SRPK2,ESR2,MYC,PPP1CC,PSMD1,ANAPC15,RC3H2,SPOP,UBE2H,RIT1,NLE1,PRPF4,BAP1,RPA3,EP300,NUP50,YAF2,CLK1,CCNI,RPL4,DGCR8,SRSF2,ATG16L1,RPS14,LIAS,WDR77,RPA2,CKS2,HEXIM1,RPLP0 |
| 5.399e-05 | -9.83 | EMC7 (ER membrane protein complex subunit 7) | protein interactions | 56851 | 151 | 65 | 19454 | 5460 |
GTF2H4,CDC42,SEC62,RND2,OTULINL,ST7,SCGB1C1,TMEM95,RPA2,EMC9,RPA3,DNAJC3,TMEM106B,HSPA8,DERL1,EMC1,CD200,PIP4P1,PXMP2,HSPA5,DNAJC22,TM4SF20,TMED5,SUB1,H2BC9,ATP1B3,SDF2L1,LMBR1L,RMDN3,SYNGR1,KLK6,SEC61B,SEC63,CCDC47,RAF1,OR4N2,EMC10,DNAJC25,TFRC,RPN1,CA14,PTRH2,SLC4A8,TSPAN3,TMT1A,LPAR2,EMC2,EMC8,KRAS,DNAJC30,CD1B,TMED7,SLC25A46,EMC4,ADCY2,EMC6,KLHL22,RHOG,ESYT1,PTPN1,PLAC9,RAC2,DNAJC1,TMED9,CD151 |
| 5.399e-05 | -9.83 | AAAS (aladin WD repeat nucleoporin) | protein interactions | 8086 | 151 | 65 | 19454 | 5460 |
UBE2H,NRP1,NTRK3,BRCA1,RHOB,AR,MYC,POPDC2,RHOJ,SEC61B,UBE2I,CIB2,LMBR1L,LORICRIN,CCNF,SSR1,RPA2,ST7,CDC42,SEC62,RND2,OTULINL,G3BP2,HSCB,EMP3,DERL1,AKAP1,ELOF1,RHOU,RPA3,RB1CC1,ESYT1,RHOG,COPS5,XPO1,LAMP3,SLC25A46,IFI16,MDFI,ATG9A,UBXN6,NUP35,RHOH,RAC2,HSD17B11,DUSP6,HRAS,PTPN1,GNAI3,CRELD1,CHMP4C,SKA3,RPN1,EZH2,NUP153,ISG15,MTCH2,FKBP8,UBE2A,TGFBR2,KRAS,NUP107,G3BP1,IGF1R,TMT1A |
| 5.423e-05 | -9.82 | RAD54L2 (RAD54 like 2) | protein interactions | 23132 | 90 | 43 | 19454 | 5460 |
ZMYM2,UBE2I,ATXN1L,FBLN5,HOMER1,DYRK1A,VIRMA,ESR2,SIAH1,TAX1BP1,AR,COP1,POU1F1,LMNB1,BRCA1,PSMA3,SQSTM1,RAP2A,RPA3,PML,PIAS1,FXR2,H1-5,SUMO1,PPARG,RPA2,EGLN3,FAM118B,HMG20A,SUMO3,SUMO2,DYRK1B,PRKX,ISX,BHLHE40,CNOT7,EGR2,TRAF2,TULP3,THAP1,TP53,ZBTB26,CBX3 |
| 5.423e-05 | -9.82 | MyD88-independent TLR3/TLR4 cascade | REACTOME pathways | R-HSA-166166 | 99 | 50 | 10285 | 3229 |
S100B,DUSP6,FOS,TAB1,CREB1,ELK1,FBXW11,TANK,AGER,JUN,LY96,NFKB1,NFKBIA,TBK1,MAP2K3,SKP1,UBB,PPP2R1A,UBA52,TLR4,MAP2K1,PTPN11,MEF2C,UBE2N,IRF3,MAPK10,MAP2K6,MAPKAPK3,TLR3,NFKBIB,ATF1,TAB2,DHX9,MEF2A,UBE2V1,IRF7,PPP2CB,TICAM1,MYD88,CD14,HMGB1,TRAF6,DUSP3,TICAM2,IKBKB,UBE2D1,BIRC2,SARM1,RPS27A,UBE2D3 |
| 5.423e-05 | -9.82 | Toll Like Receptor 3 (TLR3) Cascade | REACTOME pathways | R-HSA-168164 | 99 | 50 | 10285 | 3229 |
TANK,FBXW11,LY96,JUN,AGER,NFKB1,S100B,DUSP6,TAB1,FOS,ELK1,CREB1,PPP2R1A,UBB,UBA52,TLR4,PTPN11,MAP2K1,MEF2C,TBK1,NFKBIA,MAP2K3,SKP1,DHX9,MEF2A,IRF7,UBE2V1,TICAM1,PPP2CB,UBE2N,MAPK10,IRF3,MAPKAPK3,TLR3,MAP2K6,ATF1,TAB2,NFKBIB,SARM1,RPS27A,UBE2D3,MYD88,CD14,DUSP3,HMGB1,TRAF6,UBE2D1,BIRC2,TICAM2,IKBKB |
| 5.423e-05 | -9.82 | TRIF-mediated TLR3/TLR4 signaling | REACTOME pathways | R-HSA-937061 | 99 | 50 | 10285 | 3229 |
LY96,JUN,AGER,NFKB1,TANK,FBXW11,ELK1,CREB1,DUSP6,S100B,TAB1,FOS,PTPN11,MAP2K1,MEF2C,PPP2R1A,UBB,UBA52,TLR4,SKP1,NFKBIA,TBK1,MAP2K3,IRF7,UBE2V1,TICAM1,PPP2CB,DHX9,MEF2A,TLR3,MAPKAPK3,MAP2K6,ATF1,TAB2,NFKBIB,UBE2N,MAPK10,IRF3,UBE2D3,SARM1,RPS27A,DUSP3,HMGB1,TRAF6,UBE2D1,BIRC2,TICAM2,IKBKB,MYD88,CD14 |
| 5.446e-05 | -9.82 | lipid biosynthetic process | biological process | GO:0008610 | 592 | 218 | 18204 | 5365 |
FA2H,STAR,PRKAB1,GPAM,PPT1,GPAA1,CERS2,CYP17A1,LHB,PLAAT3,CYP11B2,MCAT,ABHD5,DPM2,FITM1,HSD17B6,AKR1B1,PCYT1B,CERK,BCKDK,MSMO1,CISH,CH25H,ORMDL3,ELOVL1,PTPMT1,FDFT1,PLP1,GGT7,CYP11B1,HSD17B3,TAFAZZIN,RDH10,PIGA,FUT9,HPGDS,HINT2,SPHK2,CBR4,ELOVL6,CYP2C9,DHRS11,INPPL1,HSD17B1,ACOT8,CYP21A2,ACAT1,MECR,PLSCR1,PIP4K2C,ALDH1A3,ST8SIA5,G6PD,SELENOI,CHKB,CFTR,SGMS2,GSTM4,CYP39A1,PGAP4,GNPAT,DECR2,SERINC1,PEDS1,FIG4,PIK3CA,FADS2,ELOVL3,PIGC,HSD17B11,INSIG2,HSD17B8,VAC14,PIK3CG,INPP4A,IP6K1,ST3GAL4,SPTSSB,B3GALT1,ABCG2,GGTA1,SCD5,SDR42E1,LARGE1,ACSS2,TMEM38B,MTMR2,NDUFAB1,PTGES3,PDSS2,HEXB,FAR2,HMGCS1,CYB5R1,FABP5,B4GALT4,HACD1,CYP27B1,SACM1L,PTGDS,ABHD2,CLN8,PGS1,TAMM41,SC5D,PTDSS1,B4GALT6,PIGY,CCDC3,ELOVL4,CYP7A1,TLCD3B,ST8SIA4,NSDHL,LIPA,FAXDC2,PIGK,SLA2,HDHD5,B4GALT3,SLC30A5,AGK,ST3GAL5,PIK3R2,KDSR,BPNT2,TSPO,PIK3R1,PGAP2,HYCC1,LIAS,INPP5E,GSTP1,CYP2R1,NPC1L1,HSD17B10,OSBP,ST6GALNAC3,PIK3R3,PRKD3,SGMS1,CYB5R3,CERS6,PLSCR3,LBR,HACD4,PLA2G15,GSTM2,AMACR,GAL3ST1,ACACA,UGCG,ACER3,SPTSSA,B3GALT2,PRPF19,ERG28,PTEN,PIP5K1A,MVD,CYP2C8,CYP1A1,ETNK2,BECN1,HYCC2,TECR,DOLK,DHRS7B,GPX4,XBP1,PTGES,PGAP3,SOCS2,SLC25A1,DEGS1,ACAA2,CDIPT,AGPAT1,MTMR6,HACD2,ABHD4,CYP27A1,FITM2,ACSL4,IMPA2,GAL3ST4,SOCS4,ERRFI1,FUT1,INPP5K,AGPAT5,MIF,ISYNA1,GGPS1,PRKAG1,SMPD2,ST3GAL1,NUS1,PIGW,PNPLA8,ACP6,ELOVL7,SOCS3,MTM1,ST3GAL2,B3GALT4,LPCAT3,CYP4F22,PLPP6,B3GALNT1,SRD5A3,OCRL,HACD3,BRCA1,CYP2D6,SOCS5,PCK2,ORMDL1 |
| 5.463e-05 | -9.81 | CASP8 (caspase 8) | protein interactions | 841 | 209 | 85 | 19454 | 5460 |
RB1,MAP1LC3A,TSC22D3,SNRPD3,CDK9,USP2,CTNNB1,MAP3K14,CRADD,TRAF6,BECN1,IKBKB,BCL2L1,CDKN1B,CDH13,GLCE,FAF1,PDIA6,PLA2G4B,EDA2R,HECTD3,TNF,AP1M1,TICAM1,PSEN1,TP53,COMMD8,FASLG,ERRFI1,SERPINB9,ERLIN2,SOX2,TRAF2,MAP1LC3B,TLR3,TFCP2,IFT57,HBP1,TOPORS,EIF2AK2,PARP2,OPTN,GRIA1,PTEN,MSN,UMPS,KLK9,TRAF1,SRC,PYCARD,CUL3,MYC,TNFAIP3,GMNN,CASP4,AR,BFAR,STK24,ATP1A3,FAS,CASC3,NLRP3,ILK,KLK5,PEA15,DEDD,BAX,FIS1,IRF3,PSEN2,PML,RPA3,BAP1,SQSTM1,PRDX6,BIRC2,RNF34,IL1B,TNFSF10,PIAS1,SUMO1,PICALM,CLIP3,RPA2,CRYAB |
| 5.463e-05 | -9.81 | BMS1 (BMS1 ribosome biogenesis factor) | protein interactions | 9790 | 209 | 85 | 19454 | 5460 |
IFI16,WWP2,CSNK2A1,DDRGK1,DDX23,CHCHD1,SNRNP70,RPS2,SRP14,RPL8,KRR1,PRR3,ARL4D,RPS10,FZR1,RPS16,CDK9,ZBTB2,SURF6,CDC5L,KLF9,FBP1,RAF1,RPSA,TP53,E2F4,H1-3,RPL15,LLPH,SNIP1,RPL31,RPL23A,RPL3,RPS24,KRAS,HMGN4,RPS13,SRSF4,RPL28,RPL17,H2BC14,MYC,RPL7A,ZNF668,DNAJC8,PSMD14,LMNB1,RHOB,H1-1,RCL1,DNAJB6,UBE2H,RPS3,EIF4A3,ZNF330,PRKRA,FGFBP1,CSNK2B,SNRNP40,RPL35,RPL13A,APEX1,RPL19,ESR2,SRPK2,VIRMA,RPS14,H1-5,FGF13,RPA2,APOBEC3C,LMNA,ZNF574,RPLP0,RPL26L1,MACROH2A2,RPA3,SIRT7,NPM3,DGCR8,UFL1,STAU1,RPL4,COIL,FTL |
| 5.527e-05 | -9.80 | SEC23B (SEC23 homolog B, COPII coat complex component) | protein interactions | 10483 | 212 | 86 | 19454 | 5460 |
TNRC6C,TOP3B,KDELR1,KLHL12,FURIN,GARRE1,TMED1,RAB1A,ZYX,IGF1R,NTRK2,CPNE2,SLC39A7,TRIM63,EPHA4,KRAS,RIGI,SAR1B,SLC25A46,FATE1,YWHAG,XPO1,YWHAH,TRAPPC2L,KCNJ10,YWHAB,STYK1,CBL,ALYREF,PHB1,CD274,PTPN1,SEC23A,EED,SUMO3,SUMO2,DCUN1D1,RAB1B,TMED9,CAND1,HSP90AB1,EGLN3,EPHB6,FUT8,UBA52,BET1,SYK,ST7,CFTR,OTULINL,FGFR1,CTBP1,RPA2,GALNT1,PIH1D1,CSNK1A1,UBE2M,SIRT7,PML,SLC39A9,RPA3,DDX39B,EP300,NF2,SKP1,SEC13,GRB10,CUL3,MYC,OST4,AR,SLC30A5,BRCA1,UBE2H,NTRK3,IGF2BP1,EPHA2,EIF4A3,SMAP2,ARF1,CCNF,SYNE4,ESR2,UGT1A1,SRPK2,VIRMA |
| 5.587e-05 | -9.79 | SREK1 (splicing regulatory glutamic acid and lysine rich protein 1) | protein interactions | 140890 | 177 | 74 | 19454 | 5460 |
MYC,HNRNPC,ZNF668,DNAJC8,STK24,RC3H2,LMNB1,H1-1,UBE2H,RPS3,SNRPD1,FGFBP1,PRKRA,RPL37A,SNRNP40,IFI6,RPL35,FBXO22,RPL13A,RPL22,RPL19,SRPK2,FGF13,RPA2,SH3GLB2,ACACA,RPA3,DDX39B,RNF113A,TRA2B,DGCR8,SRSF2,STAU1,SAP18,ZCCHC10,RAB5C,HNRNPA1,CSNK2A1,GPRASP2,DDX23,SNRNP70,RPS2,SSX2IP,HNRNPD,RPL10A,BRD3,FOLR1,SRSF1,RPS10,PAIP1,SNRPA1,SNRPD3,SRSF10,MDM2,CDC5L,NAA15,E2F4,RPSA,PAIP2B,VPS33A,ILF2,ZRANB2,RPL31,PABPC1,HNRNPA2B1,RPL23A,RPL3,SRSF7,SRSF8,H1-6,THRAP3,HNRNPK,SRSF4,SSRP1 |
| 5.634e-05 | -9.78 | - | gene3d domains | 1.20.1050.10 | 34 | 21 | 14470 | 4137 |
EEF1G,MTX2,EEF1E1,GSTT1,GSTT2B,GSTA2,GSTA1,GSTM3,CLIC4,GDAP1L1,MARS1,GSTA4,GSTM5,GSTM4,HPGDS,CLIC2,GSTM2,GSTCD,GSTO2,GSTP1,GSTO1 |
| 5.637e-05 | -9.78 | SUPV3L1 (Suv3 like RNA helicase) | protein interactions | 6832 | 137 | 60 | 19454 | 5460 |
KCTD9,PARL,CLIC4,MYC,AUH,PMPCA,CUL3,GFUS,HNRNPC,ZMAT3,TUFM,SPOP,MRPS25,ELAVL2,CDKN2AIP,RPA3,EXD2,HNRNPH2,HSPA8,GFM1,WASF3,RBFOX2,RBMS2,RPA2,MRPS34,MTRES1,MRPS9,SSBP1,ARMC1,PRR3,GATD3,PAIP1,RBM42,MRPS23,WIF1,CDC5L,GRSF1,MTRF1,TNFAIP6,HNRNPA1,SMAD4,MRPS26,HSPD1,RBM3,MRPS18B,HINT2,SRSF7,MRPS11,COX8A,HNRNPF,KRAS,MRPS18C,FASTKD5,MRPS17,HNRNPDL,IMMP2L,MRPL11,SOX2,PDHA1,ILF2 |
| 5.637e-05 | -9.78 | CDC42BPA (CDC42 binding protein kinase alpha) | protein interactions | 8476 | 137 | 60 | 19454 | 5460 |
DPP4,LAMP2,YWHAG,YWHAH,SNRNP70,RHOG,YWHAB,FCGR1A,DNAJC7,HRAS,RAB35,CTDSPL2,RAC2,GJA1,RHOH,ARF6,HNRNPL,CAV1,STX6,CDK9,DIRAS3,TOP3B,RAF1,LGR4,SNAPIN,SOX2,SKA3,VPS33A,RND3,KCTD17,KRAS,PTGES3,FLOT1,RPL28,RAB11A,CDKN2D,RPL7A,SFN,MYC,RAB2A,STK38L,AR,DNAJC5,YWHAZ,RHOB,LAMTOR1,UBE2H,SP1,LURAP1,CSNK2B,RHOJ,VIRMA,CDC42,RND2,ARL15,RHOU,STK38,SLC31A1,STX7,PYGB |
| 5.640e-05 | -9.78 | TRAF3 (TNF receptor associated factor 3) | protein interactions | 7187 | 218 | 88 | 19454 | 5460 |
WDR82,HDHD3,PDE9A,ETV6,TRAF3IP3,RNF144B,ZMYND11,MAP3K14,ATP1B1,MFN1,IFT25,TNFRSF14,PPP3CA,GSTO1,SPP1,EDA2R,EWSR1,HECTD3,GALC,MYD88,LTBR,TLR4,ABCF1,TICAM1,TFG,TNF,TRIM37,MAP1LC3B,TRAF2,DDX39A,AZI2,SNAP29,TBK1,CSNK1E,ALPL,CARD19,APEH,RNF126,TLR3,RRAS2,TNFRSF9,TRIM24,UBE2I,OPTN,CREB1,TNFRSF1B,GUCY1B1,SMURF1,VIRMA,TRAF1,DYRK1A,SRC,TAX1BP1,OTUD7B,NTAQ1,PRKACB,IRF1,TRAF3IP2,PPP1CC,RETSAT,PYCARD,CUL3,HNRNPC,ASCC1,FAS,BEX3,IL15,TLR9,BIRC2,TIFA,FAM53C,CCDC184,NMRAL1,MAVS,SQSTM1,CD40,IRF3,UGP2,EYA3,PIK3R2,STK38,CDC42,SYK,NUP62,TANK,GSTP1,APOBEC3C,MAP2K1 |
| 5.667e-05 | -9.78 | EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma) | protein interactions | 8891 | 123 | 55 | 19454 | 5460 |
CD226,RIT1,GPR17,CUL3,MYC,DUSP3,VIRMA,VPS72,SCN2B,LMBR1L,CCNF,SYT2,EIF2S2,RTRAF,EIF2B3,RPA2,PIP4P2,CDC42,SEC62,PIP4P1,EXD2,RFC4,BAP1,RPA3,NDUFB8,SMDT1,DDX1,DDRGK1,HNRNPA1,CSNK2A1,XPO1,ATG7,EIF2B2,EIF2B5,EIF2S1,VTI1B,EGLN3,FBXO32,CD4,SIGLECL1,CA14,ILF2,STX12,TP53,COMTD1,TOP3B,TULP3,CLEC2B,MAP1LC3B,G3BP1,KRAS,ABCF1,DHX9,RTCB,EFNB1 |
| 5.671e-05 | -9.78 | SRP-dependent cotranslational protein targeting to membrane, translocation | biological process | GO:0006616 | 8 | 8 | 18204 | 5365 |
SEC61B,TRAM1L1,ZFAND2B,TRAM2,SRP54,SEC61A2,TRAM1,SEC61A1 |
| 5.703e-05 | -9.77 | regulation of interleukin-8 production | biological process | GO:0032677 | 102 | 49 | 18204 | 5365 |
RAB1A,MIR129-1,ANXA4,MIR488,TLR1,CHI3L1,RIGI,TLR7,MAVS,MIR204,TIRAP,LILRA2,TLR8,MIRLET7C,TLR5,MIR146A,TLR9,MIR100,MYD88,MIR106A,CD14,TLR2,AFAP1L2,MIR920,CLEC7A,HYAL2,IL6,OTUD7B,MIR106B,CD2,TNF,IL17F,ADIPOQ,TLR3,IL10,MIR98,KLF4,TLR6,CD58,PYCARD,LEP,DDIT3,TLR4,HMGB1,SYK,PTPN22,BCL10,MIR132,IL1B |
| 5.721e-05 | -9.77 | cytoplasmic side of membrane | cellular component | GO:0098562 | 197 | 83 | 19108 | 5553 |
EFCAB7,RGS2,JUP,TRAF6,BORCS6,GNG3,GNG11,CACNB4,LITAF,KXD1,STAC3,GNB4,MYD88,KRAS,OTULINL,PPP3CA,EEF1A1,GNA14,PTPN22,GNG10,JAK2,GNG12,PKP4,CYTH1,SOCS3,BIRC2,GNA11,BLOC1S2,LILRB4,G6PD,SNX5,MIEN1,CD2,RGS1,PTPN1,GNAQ,RPS26,C2CD2L,JAK1,GNAI2,RPS28,KIT,TRAF2,GNG13,TIRAP,BORCS7,BORCS5,PTPN4,GNAO1,GNG5,BECN1,PTEN,BORCS8,KCNAB1,RPS29,SNX18,DLG1,SNAPIN,TRAF1,AP2A1,HTRA2,RACGAP1,GNAI3,GNG2,CDIP1,CHMP4C,AP2M1,IKBKB,GNG7,RAB5A,GNGT2,FERMT2,FKBP1A,RPL27,TRAF3IP2,DLG4,GNB1,GNB3,S100A6,HM13,GNAZ,AP2S1,SPPL3 |
| 5.721e-05 | -9.77 | PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) | protein interactions | 5295 | 394 | 146 | 19454 | 5460 |
CD40,HSPA8,RAB5A,EP300,SLC31A1,HSCB,CHRNA7,ZDHHC17,G3BP2,WASF3,LNX2,SYK,TSHR,IL6ST,RND2,ERAS,VDAC2,NFKBIA,RRAS2,CD3G,KBTBD2,PPP5C,TOM1L1,GNB1,JAK2,ACO2,GRB10,CUL3,PIK3R3,FAS,LAMTOR1,YWHAZ,RHOB,BRCA1,NTRK3,PIK3CG,JAK1,FGD2,EPHA4,KRAS,KIT,ETFA,IL13,IMMP2L,FLOT1,SSRP1,FASLG,RAF1,RND3,GHR,HGS,GNAQ,CRKL,DNM2,RAB35,WDR6,SRSF1,PSMB5,GJA1,RHOH,NYAP2,PIK3R1,PRPF19,INPP4A,ICOS,YWHAG,SHC3,CTNNB1,RHOG,NCK1,AHSA1,HAX1,CBL,RHOU,INPPL1,MME,TLR2,SQSTM1,TTR,HDAC3,IL1RAP,PIK3R2,FTSJ1,ARHGAP1,PRMT2,CDC42,CD2AP,HCST,XBP1,FGFR1,MET,UQCRC2,GAB1,TUBA1B,TLR8,PTEN,YES1,RHOJ,SRC,VIRMA,AKT1,RAB2A,PTPN11,IL2RB,AGAP2,IFNAR1,AR,RACGAP1,PTTG1,EPHA2,PPP1R12A,PIK3AP1,DDR1,IGF1R,NTRK2,HNRNPK,TGFBR2,PSEN1,WBP11,PIK3CA,TLR3,CTLA4,CBX3,ILF2,PSMC3,ITK,HRAS,ALYREF,RAC2,CD4,RB1,ARF6,SPPL3,CD28,EPHB6,LCP2,CAV1,DPP4,CSNK2A1,FCGR2A,GAPDH,TUBG1,PROM1,SHC1,CD247,STYK1 |
| 5.735e-05 | -9.77 | FXR1 (FMR1 autosomal homolog 1) | protein interactions | 8087 | 538 | 192 | 19454 | 5460 |
SERTAD1,CAMK2G,VWF,ERG28,MAGEA4,SRP72,YTHDF2,THOC1,ZBTB2,UBP1,LDLR,FGR,PCED1A,FBXW7,AATF,SIRT7,RPA3,MTDH,EGFL7,GRM2,PTP4A2,CDR2,SH3GLB2,DCTD,FAM161A,CCN3,ATG16L1,CCNA2,FTH1,MX1,YES1,MAGOHB,ENO1,STUB1,CCNF,RPS20,GSK3A,MAPRE1,AP2A1,PYCR2,NONO,AR,USP14,TRIM37,G3BP1,IMMP2L,AP1M1,BCKDK,TRIP4,SRSF7,GPSM3,ZC3H7A,NME1,CHMP4C,EZH2,STK16,E2F4,RAF1,KCTD10,CCAR2,OCRL,INA,LRWD1,DHX15,PHB1,DNM2,THOC2,YTHDF1,UCHL3,CYFIP2,SKP1,G3BP2,COIL,UPF3B,MCRIP2,RABAC1,LARP4B,FOXS1,MYL6,MFAP1,PRSS23,BEND5,ERVFRD-1,WDR77,H1-5,SLC48A1,ACTB,TUBB,DYNLL1,TSN,PRRC2A,PNMA1,ZMAT2,CDC7,AP2M1,HTRA2,GRB10,PYCR1,CUL3,CDC123,PRPF31,RPIA,ZNF821,TCEA2,BHLHE40,PSME1,NEFL,IK,PSMC3,SPRY1,NUPR1,TP53,FZR1,RPS16,CAND1,SLAIN2,TMPO,PDE9A,SNRNP70,TDRD7,CCDC92,TSNAX,PLEKHO1,API5,CSNK2A1,COPS5,CLU,PML,TRIM3,BAP1,CORO6,TNFAIP1,SMG5,RNF113A,HNRNPH2,LSM12,RPA2,AGO1,SRPK2,SMURF1,PAFAH1B3,PSPC1,PSMC5,TRAF7,CSNK2B,RC3H2,SPOP,ZBTB38,CCNB1,SSNA1,CA10,DCTPP1,LSM14A,GLE1,TOP3B,TRAF2,HMG20A,FUBP3,DUSP6,SRSF1,HOMER3,MAGOH,HSPB1,DDX1,WWP2,DDX50,IFI16,DDRGK1,YWHAG,YWHAH,STAU1,FXR2,UFL1,EMC1,RNF41,JAKMIP1,DDX39B,EP300,HDAC5,HSPA8,NUFIP2,PRR13,SUFU,LAP3,RALYL,LRIF1,CMTR1,CRMP1,RUSC2,MYC,PCCB,BTF3 |
| 5.737e-05 | -9.77 | ZC3H3 (zinc finger CCCH-type containing 3) | protein interactions | 23144 | 224 | 90 | 19454 | 5460 |
RPLP2,SRSF1,MRPS26,ZCCHC9,MRPL9,DDX50,MRPS35,RPS27A,AHCYL1,RPS24,MRPS11,MRFAP1L1,PNMA2,MAK16,ESR2,RPF1,RPL7L1,MRPL13,ZNF22,MIDEAS,PARP2,KIF3C,H1-1,NSA2,FTSJ3,MRPS25,ZCRB1,HNRNPC,NOP16,MRPS7,FTL,STAU1,MRPL57,NOP53,MRPL34,NGRN,NKAPD1,APOBEC3C,NOTCH2,DKC1,MALSU1,SURF6,THOC1,MRPS9,RPL32,KRR1,RPL10A,MPHOSPH10,APOBEC3F,MOV10,SPATS2L,MRPS18C,PAK1IP1,MRPS33,NOC4L,RPL3,MRPS18B,RPL23A,LTBR,MRPL52,NKRF,LLPH,RBM34,CTDSP2,APOBEC3D,RPL15,IKZF5,MRPL11,RSL24D1,MRPS21,RPL13A,TMEM74,RBMX2,TNFRSF1B,EIF2AK2,PTTG1,ELAVL2,MRPS16,RPL26,RPF2,RPL7A,UTP23,AATF,BRIX1,MRPL17,RPS15,RPL4,RPL26L1,ZNF574,MRPS34 |
| 5.755e-05 | -9.76 | RAB5IF (RAB5 interacting factor) | protein interactions | 55969 | 101 | 47 | 19454 | 5460 |
ATP6V1A,SPINT2,CORO1C,PHB1,COX4I1,AIFM1,HACD3,SLC25A12,NDUFS8,HNRNPL,COX5A,CLPX,PSMD3,NDUFB8,PDCD1,NDUFA4,RIGI,MTCH2,CHRM3,CCDC47,MTMR2,NDUFS3,PDHA1,SURF4,PTPMT1,TMEM74,CYB5R3,VDAC2,UQCRC2,TNPO3,UQCRQ,ATP5F1B,MGST3,PCCB,TOMM40,AUH,HADHA,SSR3,PHB2,NDUFS2,PDHB,UQCRC1,RFXANK,TOMM22,CYC1,HSP90B1,COX6C |
| 5.755e-05 | -9.76 | PREPL (prolyl endopeptidase like) | protein interactions | 9581 | 101 | 47 | 19454 | 5460 |
MRPL12,MRPL10,ACAA2,MRPS34,METTL2A,MTRES1,EXD2,BAP1,GFM1,MRPL41,HSCB,CRYZ,COIL,ETFBKMT,PMPCA,MRM2,AUH,MTG2,TUFM,MRPS25,MCAT,LIG3,MTG1,PARL,MRPL11,PDHA1,NDUFS6,APEH,PREPL,HSPD1,COX8A,HINT2,IMMP2L,MRPS17,PFDN5,MTRF1,CHCHD1,RHOG,MRPS26,COX4I1,SDHB,SSBP1,LDLR,FAHD1,GATD3,YBEY,TEX30 |
| 5.755e-05 | -9.76 | ZCCHC17 (zinc finger CCHC-type containing 17) | protein interactions | 51538 | 101 | 47 | 19454 | 5460 |
EED,RPL32,FOLR1,CGAS,NKAP,SUV39H1,CSNK2A1,ZCCHC10,CHCHD1,NOS1AP,RPL17,AP1M1,RPL28,H1-6,SAP30,RAF1,H2AJ,JCHAIN,BPIFB1,CSNK2B,CCNF,RPS3,SRPK2,ESR2,RPL22,RPL13A,NDN,NTAQ1,UBE2H,PTTG1,ZBTB38,MECP2,MARS1,FTL,ZDHHC17,PFKFB2,KDM1A,FXR2,ZC3H14,EHHADH,LAP3,ATG16L1,MACROH2A2,HECTD1,ZCCHC17,SDCBP,LXN |
| 5.779e-05 | -9.76 | TOMM20 (translocase of outer mitochondrial membrane 20) | protein interactions | 9804 | 227 | 91 | 19454 | 5460 |
SLC25A3,VAPB,ATP5PO,ARMCX3,H1-5,TOMM22,SUFU,PTN,UFL1,BIRC2,AKAP1,HADHA,TTC1,EXD2,FAM107A,RIT1,BTF3,TOMM40,MYC,CUL2,CHCHD3,TAB1,FAM83B,RMDN3,SARM1,VDAC2,CYB5R3,CYB5B,NUDT19,FAF2,TOMM7,NCSTN,IMMP2L,USP30,KRAS,VDAC1,ETFA,SCYL2,SLC25A5,CDC23,RHOG,TRAF6,FEM1B,DDRGK1,MARCHF5,RAB1B,FEZ1,SRSF1,RPA2,CFTR,PCK2,ATG16L1,TOMM20,ABCC2,YKT6,MAVS,RPA3,PML,CDC73,UBE2H,CISD1,FBXO7,RAB2A,C9orf72,SEC63,PRKCE,EIF2S2,MACROH2A1,OPTN,CCNF,MAP1LC3B,MTARC2,SNAP29,ATP5PB,TNRC6C,FKBP8,RIGI,NUP107,ABCE1,HSD17B10,RAB1A,ATP5PF,SFXN1,MOV10,ATP5PD,TOMM70,CDCA3,PTPN1,AIP,NDUFB4,EHBP1 |
| 5.779e-05 | -9.76 | response to bacterium | biological process | GO:0009617 | 681 | 247 | 18204 | 5365 |
CD40,RAB14,PLAC8,WDR83,EPHA2,NLRP1,CCR4,MBL2,SYK,CD1D,HMGB1,STAP1,DUSP10,PYCARD,S100A8,FCGR2B,RNF5,NFKBIL1,IL10,RBPJ,PTGFR,RNASE9,PLAAT3,TNF,ADIPOQ,DEFB121,LACRT,TRIM6,LY96,PLSCR4,CX3CR1,TUSC2,DEFB115,TICAM2,TLR10,RARRES2,TLR2,TRAF6,NLRP3,MIR17,PPM1D,THBD,CDK4,MAPKAPK3,FBXO3,TBK1,TRIB1,CYRIB,PDCD1LG2,SFTPD,F2,CLDN3,LRAT,MIR105-1,FOS,CCL2,SEMG2,CXCL10,TNFRSF14,CITED1,NFKB1,KCNJ8,CASP4,PTGER1,BPIFA2,SRC,IL18,UGT1A1,PRDX2,RNASE4,TLR4,FASLG,PDE4B,MIR140,TFEB,TAB2,SPAG11B,FAU,IDO1,CXCL8,IL17F,RGS1,LYZL4,IL13,CNP,H2BC12,SOD2,CAMP,PDCD4,IRAK4,CHMP5,NQO1,TSPO,LYG2,PTGER4,CAPN2,SLC15A2,CXCL13,OPRK1,ALPL,GPM6A,SLC17A5,CYP27B1,RBCK1,TICAM1,EPO,TLR1,DROSHA,LYZ,B2M,IL23A,IL1B,FMO1,AKT1,PTPN22,WASL,NFKBIB,CEBPE,DEFB129,SELENOS,JCHAIN,CXCL1,CCL20,MTDH,CST11,WFDC13,ISG15,TLR6,CCR7,IL1A,MAP2K3,FCN2,PPP1R11,NFKBIA,NOTCH2,PLSCR3,ROMO1,GPX1,IL18BP,CXCL11,LIAS,TF,MIR95,RAB29,DEFB116,GSTP1,FGF10,TNFAIP3,DEFB1,GJB2,CD14,CCR5,MIR20A,HNRNPA0,RPL13A,XBP1,CNR1,TMEM229B,LITAF,CYP1A1,MIRLET7B,PLAA,DHX15,MIR187,TMEM255A,TIRAP,ACP5,NLRP6,JAK2,H2BC11,LYZL6,OAS1,DIO2,DEFB114,FCGR1A,MRC1,HDAC5,PRKCE,MIR545,CHGA,SHC1,IRF8,LTA,FOSL2,LILRB1,REN,BCL10,CD274,IL12A,FOXP3,RPL39,ST13,PELI1,TNFSF8,IRF3,CSF2,IL12B,FCER1G,TLR3,RNASE6,AKAP12,FGR,DEFB124,MIR223,FOXP1,CXCL9,PRDX3,MIR142,CD86,MMP9,LSM5,IFNAR1,IL6,PTGER2,PI3,OCIAD2,SNX3,MGST2,LEAP2,WFDC5,MYD88,MIR342,MIR421,SLPI,GFI1,TLR9,PCK2,TNFRSF1B,CXCL3,FABP4,MIR146A,CD4,MIR21,CDC73,CCDC186,CLDN1,RNASE1,MAVS,CAV1,NCR3LG1,LDOC1,MEF2C,CD80,CD36,RAB1A,HP,OPTN |
| 5.788e-05 | -9.76 | USP4 (ubiquitin specific peptidase 4) | protein interactions | 7375 | 157 | 67 | 19454 | 5460 |
LSM8,PRPF4,RAB30,MAVS,PPIH,LSM2,ANXA7,KLF4,INSYN2A,CDKN1A,TRIM54,ELMO1,TCEAL1,JUNB,VIRMA,CDPF1,PSMA6,PSMC5,PTEN,RBBP8,ATP1B3,LSM6,STN1,SLX1A,AKT1,SFN,MCCD1,RHEB,PRPF31,BRAP,LSM4,HUWE1,KRAS,TRIM63,MEPCE,SMN1,RIGI,PICK1,PCNA,TRIM21,IRF8,SART3,SNAP29,VDR,TP53,TRAF2,PGM1,PRNP,PPIA,PTP4A3,NPC2,EEF1AKMT3,EIF4E2,RB1,IKBKB,SMAD4,TCEAL9,TRAF6,USP15,UBXN6,PRPF19,IRF4,YWHAH,CTNNB1,EDC3,EXOC1,ATP1B1 |
| 5.815e-05 | -9.75 | TOMM5 (translocase of outer mitochondrial membrane 5) | protein interactions | 401505 | 112 | 51 | 19454 | 5460 |
ADCK1,NDUFS8,OCIAD2,PHB1,NDUFB4,COX4I1,CORO1C,ATP6V1A,ESYT1,HNRNPD,NDUFB8,SYNJ2BP,PPIB,FKBP8,TOMM6,RAB1A,NDUFA4,ERG28,EMC2,RPN1,RAB19,PDHA1,NDUFS3,SLC25A20,MTCH2,E2F4,MGST3,ATP5F1B,UQCRQ,UQCRC2,VDAC2,DNAJC10,ATP1A1,RAB2A,TOMM40,PCCB,PDHB,NDUFS2,PHB2,GNB4,DAD1,HADHA,AKAP1,HSP90B1,CYC1,SLC25A3,NDUFA5,TOMM22,PGRMC1,UQCRC1,CD59 |
| 5.815e-05 | -9.75 | response to topologically incorrect protein | biological process | GO:0035966 | 134 | 61 | 18204 | 5365 |
DNAJC10,STUB1,CLU,TRAM1,TMBIM6,HSPA8,SERPINH1,PTPN1,HSPD1,SDF2L1,DERL2,TOR1B,DNAJC4,HSP90AA1,HDAC6,ATF3,DDIT3,SELENOS,CREB3,ATF4,UBE2W,VAPB,KLHL15,BAK1,BAX,ERLEC1,HSPB1,HSPB2,FAF2,CREB3L4,KBTBD6,CUL3,HSPA5,CREBZF,XBP1,UFD1,BAG3,EIF2AK2,ERO1A,EDEM2,PACRG,CCND1,DNAJC3,HSPE1,DNAJB9,DNAJB2,JKAMP,HSPB8,NFE2L2,DNAJB4,EDEM1,CAV1,OS9,RPAP2,HSP90AB1,CDK5RAP3,EDEM3,OPTN,EIF2S1,RNF126,DERL1 |
| 5.827e-05 | -9.75 | negative regulation of protein modification process | biological process | GO:0031400 | 421 | 161 | 18204 | 5365 |
LILRB4,DNAJC3,PAQR3,MIR146A,PSEN1,RPL23,BEX3,ARPP19,MIR212,SFN,IGFBP3,PPARG,UFL1,MIR218-1,NTRK3,UBE2B,MIR711,IMPACT,SOCS5,CDKN1B,CNKSR3,PKIG,TSPO,CAV3,UBASH3B,CEP85,NF2,FKBP1B,SWAP70,IVNS1ABP,TRIM44,IKBKB,CAV1,PAX6,SOCS3,MIR137,LGALS3,MAD2L2,SQSTM1,TRIM27,PARD6A,THY1,CTDSP2,TRIM21,PRNP,ZBED3,SNTA1,SOCS4,SPRY1,HEXIM1,ANGPT1,ERRFI1,BAG2,PTPN1,MIR132,INPP5K,PTPRQ,CAMLG,MIR15A,DUSP19,HSPB1,MIR34A,GNAQ,PPIA,FLCN,SFRP1,RTRAF,BAX,ROCK1,PDCD4,IFNG,FKBP8,SVBP,SPOPL,YWHAG,TAF7,MIR106B,CRKL,TRIB1,SLC8A1,IL2,PLAA,PAK2,CTDSP1,CBL,PID1,GADD45A,G6PD,CAMK2N2,GSKIP,RGN,MIR20A,YWHAB,ADNP,RB1,P3H1,DEFB114,PPP1R8,PRKCE,CRY1,DCUN1D3,TESK1,CDK5RAP3,LRP6,HINT2,MACROH2A1,CDKN1A,PKIB,TSG101,MAD2L1,DUSP6,PTEN,FKBP1A,ATP2B4,STK38,DUSP10,C9orf72,PYCARD,PKIA,HDAC6,PRR5L,ISG15,RPS7,TPPP,TBC1D24,IL1B,MINAR1,RGS2,CDK5,HEXIM2,DKK1,VPS28,AKT1,HMG20A,DNAJC10,PTPN22,GCLC,CORO1C,PPP1R1B,RPS3,NCK1,DUSP1,SPRED2,GSTP1,HYAL2,BAK1,CRTAP,TNFAIP3,CTNNB1,SIRT7,ROCK2,DUSP22,MIR24-1,MIR101-1,CHP1,DUSP3,SPRED1,ADIPOQ,TNF,DBNDD1,CAMK2N1 |
| 5.835e-05 | -9.75 | SF3B6 (splicing factor 3b subunit 6) | protein interactions | 51639 | 183 | 76 | 19454 | 5460 |
TPBG,RAF1,JCHAIN,RPS11,PPP4C,SF3B5,IFT22,SNRPE,MOB3C,NUPR1,OTULIN,DDX42,SMNDC1,CHMP4C,SOS2,SRSF7,HSD17B10,RPS24,SNIP1,HSPD1,SNRPG,SNRNP48,THRAP3,VDAC1,HNRNPA1,TRA2A,PRPF19,NFKB1,LAMP2,RBM17,SKIC8,EED,SRSF1,PHB1,CDC5L,DHX15,CAND1,SNRPD3,SNRPA1,TOP1,ATG16L1,SF3A1,HEXIM1,USP39,RPA2,ZNF326,SF3B1,EP300,DDX46,SNRPA,RPA3,UFL1,RPL4,TTC33,SNRPB,DNAJC8,MYC,SUGP1,UBE2H,THOC6,ZCRB1,LMNB1,FTSJ3,SRP54,SNRPD1,SNRPD2,SF3B4,SF3B6,CCNF,RAN,SCNM1,DLST,SNRPB2,ESR2,VIRMA,SNRNP40 |
| 5.847e-05 | -9.75 | MTFR2 (mitochondrial fission regulator 2) | protein interactions | 113115 | 44 | 25 | 19454 | 5460 |
FKBP8,PXMP2,TOMM20,PHB2,GABBR1,DDIT3,AKAP1,EXD2,TFIP11,EZH2,CFTR,NPY2R,MTCH2,TOMM22,MGST3,RMDN3,GUCY1B1,AIFM1,HTRA2,DICER1,FIS1,TRIM23,SLC25A46,CUL3,MARCHF5 |
| 5.847e-05 | -9.75 | P2RY1 (purinergic receptor P2Y1) | protein interactions | 5028 | 44 | 25 | 19454 | 5460 |
SCAMP2,RETREG3,ATP5F1B,DERL2,SC5D,VKORC1L1,ATP5PD,MSMO1,SERINC3,EI24,VPS26A,ATP5F1A,OSBPL8,TMEM87A,GNA11,CERS2,GPM6A,CERS6,SACM1L,ATP5PB,ADORA1,SLC19A2,YIPF3,ATP5PO,NHERF1 |
| 5.850e-05 | -9.75 | EIF3I (eukaryotic translation initiation factor 3 subunit I) | protein interactions | 8668 | 233 | 93 | 19454 | 5460 |
SUB1,AR,EIF3G,PDCD4,UBE2H,PSPC1,CCNF,METAP2,VIRMA,ATG16L1,TPT1,EIF3J,CFTR,METTL14,UBE2M,HEXIM1,BAP1,SOD1,PPM1G,SIRT7,HMGB1,EIF4E,NFKB1,USP3,CSNK2A1,CD81,CRBN,CDK12,TES,CD4,FZR1,RPS16,EIF2B5,RBM42,LMAN1,TP53,DNAJC2,SRP72,RNF8,METTL18,STX18,HSD17B10,HUWE1,EIF4EBP2,NEDD8,TGFBR2,RPS13,EIF3E,MYC,ACO2,CUL3,SFN,PSMD1,FAS,YWHAZ,BRCA1,ICAM1,RIT1,RAN,EIF3K,RPL37A,SEC61B,IFT172,EIF4A2,PSMB6,ESR2,RPL10,KCTD12,EIF4B,NMRAL1,RAB5A,EP300,TRA2B,EIF1B,UFL1,G3BP2,WWP2,YWHAG,DDRGK1,EIF3D,PPM1B,DRG1,LYAR,B3GNT2,SKA3,EZH2,RPS11,NDUFB5,RUVBL2,SRSF7,G3BP1,KRAS,RAD21 |
| 5.870e-05 | -9.74 | Sm | smart domains | SM00651 | 20 | 14 | 9717 | 2575 |
SNRPD3,LSM5,LSM6,LSM4,SNRPD2,SNRPB,SNRPG,LSM10,LSM8,SNRPE,LSM3,SNRPN,LSM2,SNRPD1 |
| 5.895e-05 | -9.74 | IRF3 (interferon regulatory factor 3) | protein interactions | 3661 | 140 | 61 | 19454 | 5460 |
TANK,PSMB7,CSNK1G3,PSEN2,IRF3,TLR2,SQSTM1,MAVS,EP300,IRF7,HDAC3,UFL1,TICAM2,CREBBP,AKT1,RALB,TRAF3IP2,FBXO7,OTUD7B,KPNA6,ATP1A3,PSMD14,TEX36,HSP90AA1,SMAD2,CDKL2,UBE2H,SGTA,APEX1,CCDC47,TBK1,MAP1LC3B,TRAF2,SYNGR3,OTULIN,NUDT5,TRIM21,EWSR1,UBE3A,PSMA5,TRIM26,KIT,TRIM63,KPNA2,TICAM1,RIGI,FLOT1,CXCL10,FKBP8,PRDX1,XPO1,PPIB,MAP3K14,SMAD4,TRAF6,CBL,WDR82,RB1,TOMM70,SLMAP,LRWD1 |
| 5.895e-05 | -9.74 | STEAP3 (STEAP3 metalloreductase) | protein interactions | 55240 | 140 | 61 | 19454 | 5460 |
SEC63,RANBP6,RHOJ,BAD,VAMP3,FAM177A1,DPEP1,CTNNA1,SETD7,TMEM179B,LAMTOR1,RHOB,MBLAC2,DNAJC5,RAB2A,RAB11A,SCN3B,STX7,BNIP3L,RAB9A,RAB5A,MTDH,RHOU,CDC42,RND2,TPT1,BET1,STX6,DIRAS3,LMAN1,CAV1,ARF6,RHOH,GJA1,THY1,RAC2,HRAS,RAB35,RPRM,RHOG,MED29,LAMP3,ATG9A,DPP4,LAMP2,RAB5C,PDE2A,KRAS,RAB3B,NTRK2,MRFAP1L1,GARRE1,CD83,NDUFA4,CTXN1,RND3,RPN1,TFRC,RAB4A,TOP3B,PARM1 |
| 5.895e-05 | -9.74 | DHCR24 (24-dehydrocholesterol reductase) | protein interactions | 1718 | 140 | 61 | 19454 | 5460 |
CUL3,BTF3,SYP,ATP1A3,PSMD14,ENDOD1,ANAPC4,LMBR1L,CCNF,SYNGR1,SLC30A7,SLC1A1,SEC61B,STAT1,COPE,NDUFAF4,RABL3,PGRMC1,FUNDC1,RPA2,LMNA,SLC12A2,SIGMAR1,CAV2,RPA3,TSPAN15,VIPR1,DERL1,RTN4,LPAR1,STAU1,CCR4,ATG9A,ADIPOR2,WWP2,PTPN5,SLC2A1,P2RY1,IKBKB,RB1CC1,POU5F1,ARMC8,HRAS,PTPN1,CD274,FBXO32,ACTA2,PHB1,HSD17B11,AGK,TMPO,FUNDC2,EGLN3,MDM2,UBL4A,TP53,STIM1,ATP5PF,NDUFA4,LPAR2,PSEN1 |
| 5.898e-05 | -9.74 | NOP53 (NOP53 ribosome biogenesis factor) | protein interactions | 29997 | 284 | 110 | 19454 | 5460 |
SOX2,H1-3,MAK16,EZH2,MOB3C,RHOBTB1,RPL31,RPS24,PSMA1,KRAS,RPS27A,MRPS35,IFI16,DDRGK1,DDX23,ZCCHC9,LHX2,MRPS26,SRSF1,RPL8,LYAR,RPL7,RPS10,BET1,SYK,NGRN,EP300,NOP53,ZNF692,FTL,RAB11A,MYC,ZNF668,FTSJ3,MRPS25,ZCRB1,PSKH1,FYTTD1,H1-1,NSA2,RIT1,ZNF189,RPS9,RPL37A,SNRNP40,RPL7L1,RPL35,APEX1,RPL10,ESR2,RPL19,RPSA,TP53,AURKAIP1,RBM34,RPL23A,RPL3,IMP4,TOLLIP,MRPS33,RIGI,RPL17,MRPS18C,GRSF1,MOV10,CSNK2A1,MPHOSPH10,USP15,RPL10A,RPS2,NOL12,KRR1,MRPS9,ARL4D,PRR3,CAND1,SURF6,KLF9,MDM2,DKC1,SPTBN1,CPSF4,CFTR,MRPS34,RPLP0,RPL26L1,SIRT7,RAB9A,RPL4,RPS15,EIF5B,DGCR8,NPM3,NF2,BRIX1,RPL7A,RPF2,CEP70,PRKACB,CASC3,UHMK1,ZNF330,EIF2AK2,PTEN,TRIM27,PRKRA,FGFBP1,CSNK2B,RPL13A,SRPK2 |
| 5.913e-05 | -9.74 | DDX39A (DExD-box helicase 39A) | protein interactions | 10212 | 1081 | 360 | 19454 | 5460 |
GIN1,POLR2C,RPN1,IL7,AQP3,PCDH17,SLC17A5,CIPC,IRAK4,COPS4,SSRP1,FOXP4,WDR19,BABAM1,PMP22,PTPN5,NABP1,PRPF18,OPRL1,CEP19,AFAP1L2,RNF182,ELFN2,NUDT3,SLC48A1,MAPKAPK5,PAOX,DAAM1,FOXS1,TXNL1,RNF11,PXMP2,PPP2R2C,UCHL3,HSCB,MRPL57,HSD17B1,IRF1,SLC16A4,AUH,ZNF250,LIN7B,ARHGAP19,TRIQK,BRCA1,SNRPD1,GPR89A,ACTB,ACCS,FCF1,GBE1,KLHL26,ITGB8,TSPAN17,CPNE2,EGFL8,SPATA6,TTC8,HHIP,RERG,ZSCAN5A,ANAPC11,RNF115,CDK2AP2,NOC4L,SLC35A5,PMM2,EMX2,CDK9,MSMO1,AK5,THOC1,RASGEF1C,CDK7,ATP6V0E1,SF3A1,WDR5B,ZNF671,WTAP,NUDT12,MPV17L2,SPCS2,RPA3,FAM222B,LRRTM2,LSM8,ARMCX5,FBXW7,HMOX2,LCORL,HEXIM2,CAMK2N1,VIRMA,NDN,NREP,TUBA1A,SPG21,ABHD6,SLC25A44,SLC4A8,NDUFA12,GHR,CLDN12,NIM1K,KGD4,DDRGK1,IFI16,IFT25,VSTM4,DENND6B,NCK1,ACHE,KCNG3,HNRNPL,SUMO2,TIRAP,TMC7,AKIP1,BRI3,BET1,ZC3H14,EIF4B,PDSS2,DDX39B,UFL1,ATG101,SNRPB,TBC1D1,MYC,CNRIP1,PHF7,PDF,KCNA3,RPS26,H1-1,TMEM179B,PSMD14,ESR2,SSH3,PTPRZ1,TVP23B,EMILIN3,KBTBD4,INSIG2,NUPR1,PIK3CA,DXO,METTL18,KLHL24,POLE4,RPIA,HNRNPK,COMMD5,ELOC,API5,CEP15,TMEM19,CXCL12,LSM3,MED29,ALYREF,IER3,MYL12A,AGO1,KCNJ11,DYRK2,HIKESHI,IPP,MAIP1,TMEM263,TRIM3,PRKACB,CEP70,SLC6A1,PDCD4,UBE2H,SORD,ENDOD1,CHCHD4,AMIGO1,TBCCD1,RBM38,PGGT1B,SSBP3,TMEM59L,EZH2,VAMP2,ZC3H7A,SLC35G2,FHL3,TRIP4,PLPP6,ETFA,ZBTB14,AHSA1,BCL2L1,TRAF6,CYP27B1,THOC2,PPP2CB,PHB1,LCA5L,KCTD10,PRKAB1,PSRC1,FAM3C,SAT1,TMEM74B,TMEM185A,CXCR4,HAND2,SOCS5,KDSR,NDUFB6,CUL3,FAM229A,FOXI3,TMEM100,CTSK,LMNB1,OVGP1,ING1,DDX39A,SLC25A20,STX8,MRPL22,SOCS2,TCP11L2,CD80,SERTAD1,TMEM199,FOXC2,CDC37L1,STYK1,EPOP,SLC2A1,MED21,NOVA1,GK5,CD9,EEF1AKMT3,TOP1,ATG16L1,WDR83,MYL12B,GRM2,MNS1,MAVS,ORMDL1,HYCC2,USP14,FLRT3,TMEM255A,BBS5,UBE2I,OPTN,CIB2,EAF2,F11R,KCNJ3,NR1H2,ISG15,SOX2,MSX2,NAA16,ARFGEF1,PPIL3,PIR,METTL21A,ZC4H2,TPPP,SEC61G,HDAC11,ICAM3,SREK1IP1,TMEM87A,CMTR2,NDUFB5,PABPC1,UCN,LEPROTL1,RWDD4,SLC38A9,NT5C2,GSTM3,SIVA1,AGR2,DUS4L,EED,LAPTM4A,CEP57L1,TOR1B,RMND1,VAMP1,LDAH,SLC19A2,FBXO42,NMRK1,RAB30,HSPA8,TIFA,RAP2A,YAF2,SNRPA,PRCP,SSR3,TIMP1,OST4,PIWIL4,PHOSPHO2,ARMC7,PLA2G15,CHTOP,USP38,TCEAL1,CYP26A1,URM1,EGR2,GDE1,NKX3-2,ACADSB,STRADB,MOB3B,TOLLIP,ACOT8,TMEM144,DNAJB2,SLC35A1,RNF128,COQ10B,NDUFB4,ANKRD34B,CDC5L,SLAIN2,P2RY11,MAEL,UBE2W,TRIM36,CYB5R4,RPA2,VPS4B,TMEM81,LCP1,HCFC2,TSPAN5,ZNF322,SLC25A51,MGST2,FOXA3,ZBTB38,SERTAD3,RAP2C,CRLF3,ADAMTS20,MOB4,PAFAH1B3,MYG1,SMURF1,SRPK2,SC5D |
| 5.947e-05 | -9.73 | PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase) | protein interactions | 10606 | 245 | 97 | 19454 | 5460 |
FOLR1,SWAP70,PHB1,HNRNPL,PRDX1,PDIA3,DDRGK1,TRAF6,FKBP4,AGR2,MED4,HSPB1,YWHAB,UBE3A,UFM1,KRAS,ETFA,HNRNPDL,SAR1B,IMPA2,TXNRD1,SUPT5H,GABARAPL1,MSX2,PRKAG1,MOB3C,AP2S1,ARF1,DLST,ZMYM2,PRDX2,FBXO22,MYC,PYCR1,CUL3,SAMHD1,BRCA1,RIT1,SERPINH1,HSPA8,CRY1,TTC1,UFL1,EMC1,FXR2,TMEM177,STAU1,SHMT1,NEK7,PIH1D1,SYNCRIP,PREP,MIF,SHC1,FAF1,EMC2,HUWE1,HSPE1,RPIA,PRDX4,RRM1,MAP1LC3B,GLRX5,GINS4,ACTR2,UBE2B,DNAJC2,POLR2G,CCNF,NUDT18,STUB1,CTTN,MOB4,ZBTB18,UBE2I,VIRMA,PYCR2,AR,NIF3L1,GLOD4,CDC73,UBE2H,RPA3,BAP1,SIRT7,SLC2A3,SQSTM1,FBXW7,UGP2,PSMC4,ATG16L1,GABARAPL2,RPA2,PTP4A2,HEXIM1,UBE2M,WTAP |
| 5.951e-05 | -9.73 | LIG3 (DNA ligase 3) | protein interactions | 3980 | 186 | 77 | 19454 | 5460 |
JUN,SOX2,H2AX,TOP3B,MAX,SPC24,TP53,RBPJ,FURIN,NUPR1,APTX,EZH2,CBX3,NDUFS6,H2BC1,EMC2,RPL31,PREPL,SSRP1,MDC1,H3C1,HDAC6,CTNNB1,MOV10,IFI16,HMGA1,CLPX,BRD3,EMX2,FOXP1,CRBN,POLB,DDX23,H2AC4,EED,H2AZ1,TMPO,MACROD1,TOP1,ST7,TPT1,LMNA,KLF3,PPARG,RPA2,RPRD1B,HSP90B1,RNF146,EXOSC4,FOXD3,RPA3,BAP1,NBN,PML,XRCC5,OGDHL,HSPA5,FTL,NF2,NUCKS1,BTF3,RACGAP1,AR,FMC1,MYC,PYCARD,BAX,TDP1,CSNK2B,IRF2,ZNF330,TNFRSF1B,PARP2,CMTR1,VIRMA,ESR2,APEX1 |
| 5.956e-05 | -9.73 | nerve_sheath | COSMIC cancer mutations | nerve_sheath | 48 | 27 | 16828 | 4835 |
IDH1,KRAS,PTEN,TERT,FGFR1,JAK2,ETV6,NF2,TP53,KIT,MET,NFE2L2,EWSR1,SS18,STK11,GNAQ,KLF4,HRAS,EZH2,CDH11,SMARCB1,PIK3CA,IDH2,AKT1,RB1,GNA11,CTNNB1 |
| 5.973e-05 | -9.73 | TGFBR1 (transforming growth factor beta receptor 1) | protein interactions | 7046 | 251 | 99 | 19454 | 5460 |
UBE2E3,NRP1,EPHA2,FKBP1B,SMAD2,SKAP2,USP14,RHOJ,SMURF1,ACVR1C,CDC20,UBB,VIRMA,STUB1,TSSK1B,RNF146,OXSR1,PARD6A,SPTBN1,UBA52,CDC42,KLRD1,PIK3R2,CDC42EP4,CLU,RHOU,PML,ARHGEF6,PRPF4,MYT1L,SQSTM1,RAB33B,SMAD4,FBXO34,USP15,DPP4,BMPR1B,USP2,SAT2,CAV1,ITK,SMAD3,ARL4D,CDK6,ENC1,BMPR2,ACVR1,SFTPC,TAB2,IL20RB,PREB,CDK4,CLEC2B,SMAD1,TNFSF8,RAB3B,TOLLIP,TGFBR2,PSEN1,STX8,TTPAL,RAB13,PSMD14,RHOB,PLEKHJ1,HSP90AA1,KLHL1,RAN,CSNK1A1,FKBP1A,RASL12,RNF5,RNF11,RGS19,RTKN,TTC1,RAP2A,EP300,RHOG,IKBKB,SKIC8,TRAF6,TGFB3,TGFB2,PIK3R1,ICAM2,CTNNB1,NKIRAS1,CDK17,RHOH,PEG10,GNB3,RAB6B,PLD3,NUP37,CHN2,ARHGAP15,RPS27A,RPAP3 |
| 5.974e-05 | -9.73 | TRIM71 (tripartite motif containing 71) | protein interactions | 131405 | 64 | 33 | 19454 | 5460 |
MIR155,NOP53,SRSF4,MIR29A,RPL31,DHX9,EZH2,THAP2,PABPC5,RAF1,MIR100,TP53,MIR15A,MIR1-2,CDKN1A,FGF13,RPS16,RPL35,SURF6,RPL19,RPS3,KRR1,PRR3,TRAK2,MIR25,MIR1-1,IGF2BP1,H1-1,DICER1,SYCE3,RPL26,ZNF668,E4F1 |
| 5.974e-05 | -9.73 | TBXA2R (thromboxane A2 receptor) | protein interactions | 6915 | 64 | 33 | 19454 | 5460 |
ZDHHC17,PRDX4,BMPR1A,GNA11,GHRL,FGFR1,PRKCA,AAMP,SLC25A24,GNAQ,RAF1,ADIPOR1,SLC19A2,RPGRIP1L,SC5D,GNB1,GNAI2,KCNMB1,RETREG3,MFSD5,PLCB2,NME2,YWHAZ,KCNMA1,ZDHHC15,CSK,SIVA1,RAB11A,GJB2,ARL6IP6,GNG2,SLC35B4,SLC41A1 |
| 5.986e-05 | -9.72 | SPAG9 (sperm associated antigen 9) | protein interactions | 9043 | 257 | 101 | 19454 | 5460 |
RBBP4,PSMD6,EIF4A2,APEX1,NFKBIA,PRMT5,BRCA1,KIAA1191,LAMTOR1,MYC,MCM4,PSMD1,SYNPR,PSMC1,TSPAN15,RCCD1,RFC4,EP300,HSPA8,EMC9,PSMB7,TMEM184B,NEK7,FAM219B,DDX23,PPM1K,MED4,FAM174A,LAMP2,PSMD3,HNRNPA1,RUVBL1,HNRNPF,ARL5B,RBBP7,PSMA1,ZBED1,MCM6,CD83,NDUFB5,RUVBL2,MTA2,MED9,ARFGEF1,ARFGAP1,MAX,PPP2R1A,ADRM1,ABHD17A,MAP3K3,VIRMA,CCNF,SGTA,SLC1A1,PSMC5,SYNGR1,IVNS1ABP,SYP,BMERB1,FAM163B,NONO,SMC4,ATG4C,HSPA5,PIP4P1,PRPF4,SIRT7,PML,BAP1,RAB9A,METTL14,PTP4A2,ACACA,UBE2M,MREG,RPS14,SYNGR2,MND1,CD2AP,GTF3C4,SPPL3,ARF6,ARL10,CD274,USP15,STYK1,ZNF24,NFKB1,TPM3,PPM1D,KPNA2,NUP107,HUWE1,VTA1,DMAP1,PSMC3,TP53,COMTD1,MAP1LC3B,ACTR1A,MAP2K3 |
| 5.989e-05 | -9.72 | PALD1 (phosphatase domain containing paladin 1) | protein interactions | 27143 | 77 | 38 | 19454 | 5460 |
FIS1,RHOG,LAMTOR1,RHOB,TLR9,LAMP2,SLC25A46,RAB11A,NXPH3,CUL3,ARF6,RAC2,SEC61B,RAB35,PTPN1,LMNA,RPA2,AQP3,RAB4A,SEC62,CDC42,ST7,TOP3B,MTCH2,UNC119B,TACR3,PXMP2,KRAS,IRF7,LSM12,DERL1,RAB9A,AKAP1,BAG2,MACIR,RPA3,GADD45A,TMT1A |
| 5.996e-05 | -9.72 | NKAP (NFKB activating protein) | protein interactions | 79576 | 126 | 56 | 19454 | 5460 |
RSBN1L,BRD3,ARMC8,ANKRD50,DDX23,CHCHD1,SNRNP70,NOS1AP,CSNK2A1,YWHAG,DDRGK1,ZCCHC10,FRA10AC1,AKAP17A,DHX15,NKAP,LYAR,SYNCRIP,MYEF2,TOPORS,CHMP4C,YIPF4,THAP1,TBK1,RAF1,BPIFA2,AP1M1,H1-6,HECTD3,SREK1IP1,SNIP1,UBE2H,PPIG,CHCHD4,RC3H2,RIOK2,CEP70,SNRPB,MYC,SRPK2,ESR2,BUB3,CSNK2B,AP2M1,RBMX2,CCNF,DYRK2,CDK1,ZCCHC17,ZC3H14,FTL,RNF113A,LCN1,SNRPA,UPF3B,NKAPD1 |
| 5.996e-05 | -9.72 | POLR2I (RNA polymerase II subunit I) | protein interactions | 5438 | 126 | 56 | 19454 | 5460 |
PFDN2,POLR1B,UBE2H,CDKN2AIP,RIT1,MED10,BRCA1,LMNB1,LMO2,MYC,CUL3,MED22,POLR2B,SRC,MED17,POLR3B,POLR2F,INTS12,POLR3H,FBLN5,MED31,PIH1D1,RPRD1B,WWP1,MED30,POLR1D,POLR1H,MED11,ATP6V1G2,MED13L,SNRPA,MED4,MED27,MED21,MED29,XPO1,COPS5,WWP2,DCUN1D1,GTF2B,RPRD1A,POLR2L,POLR2G,POLR2C,POLR2D,CDK8,RPAP2,PSMB9,MED9,SUPT5H,PDRG1,KRAS,DNAAF10,RPAP3,CPNE2,FAM168A |
| 6.000e-05 | -9.72 | ATF4 (activating transcription factor 4) | protein interactions | 468 | 93 | 44 | 19454 | 5460 |
ASB7,POU5F1,MOV10,NDC80,MDM2,EGLN3,NAP1L5,GTF2B,CEBPG,LDLR,NFE2L2,DISC1,POLR2C,SNAP29,BATF,SOX2,JUN,NFE2L1,APH1A,AP1M1,NFE2,ATF3,GCC1,LMNB1,FBXW11,TBC1D25,CREB3,CREBBP,ATF4,DAPK3,CEBPE,EGLN2,JUNB,NFKBIA,TRIM24,GTF2F2,CREBZF,GABBR1,TTR,LDOC1,FOS,CCDC106,EP300,DDIT3 |
| 6.000e-05 | -9.72 | MRPL35 (mitochondrial ribosomal protein L35) | protein interactions | 51318 | 93 | 44 | 19454 | 5460 |
MRPL10,RBMS2,MRPL12,ZNF574,ACACA,MTRES1,MRPS18A,MRPL34,MRPL20,FTL,HSCB,RPL4,MRPL41,MRPL40,MRPL16,RACGAP1,MYC,MRPL13,MRPL53,METAP2,RPL10,RPL19,RANBP6,MRPL23,RPL35,H2AX,RAF1,MRPL47,MRPL33,MRPL49,MRPL51,RPL23A,SRSF7,MRPL52,RPL17,H1-6,MRPL9,HNRNPA1,MTRF1,MRPL18,PRR3,FAHD1,MALSU1,MRPL50 |
| 6.062e-05 | -9.71 | CBX4 (chromobox 4) | protein interactions | 8535 | 189 | 78 | 19454 | 5460 |
CDK9,TOP1,WDR82,EED,RB1,RPL8,BRD3,YWHAB,KDM2A,H2AC4,YWHAH,PPIL4,TMA16,CSNK2A1,YWHAG,SUV39H1,MEPCE,PCGF6,H3C1,PCGF3,ZBED1,SATB1,KCTD17,SCML1,HNRNPK,RING1,FAM76B,RPL23A,HAPSTR1,TRIM21,MORC2,GADD45A,TAF2,PHC1,DDX42,PNMA2,JUN,SOX2,ISG15,MED9,PPP1R10,VIRMA,ESR2,CSNK2B,UBE2I,PSPC1,RPS3,FBLN5,CTTN,SPOP,YWHAZ,NONO,SLC25A1,CREBBP,SFN,COIL,G3BP2,SKP1,GTF2I,RPS15,PCGF2,YAF2,TTC1,IMPACT,HELLS,PML,MAPKAPK3,ATP5MK,MFAP1,NUFIP2,MYL6,LMNA,TOX4,SDC2,CTBP1,MX1,LNX2,SUMO1 |
| 6.096e-05 | -9.71 | CCND3 (cyclin D3) | protein interactions | 896 | 85 | 41 | 19454 | 5460 |
CDK4,CCND1,DMTF1,VDR,TOP3B,CCNA2,CDKN1A,PPP1CB,CRABP2,NME1,CDK1,HGS,TFIP11,SH3GLB2,CDKN2C,FHL3,MNS1,CDK5,PCNA,RIGI,CLU,PSMC1,STAP1,CDKN2D,MAPK4,CREBBP,PPP1CC,POLR3GL,RUNX1,FAS,MAF1,CDKN1B,KLK5,LSM3,EIF3K,VGLL4,CDK6,RB1,TSG101,HNRNPL,DYRK1A |
| 6.096e-05 | -9.71 | MYD88 (MYD88 innate immune signal transduction adaptor) | protein interactions | 4615 | 85 | 41 | 19454 | 5460 |
MYD88,PIK3AP1,TLR4,SPOPL,TLR7,TLR2,RNF113A,SQSTM1,IL1RAP,IRF7,PELI1,CYTH2,IRAK4,SYK,TIRAP,TLR3,TLR5,UBAP1,SMAD3,TLR8,TSG101,BST2,SARM1,TXN,HNRNPL,SPPL3,SIAH1,MDM2,SMURF1,PRDX1,IRF4,NTAQ1,HDAC6,CISH,SIAH2,GLOD4,SPOP,TLR9,TLR10,TRAF6,RNF152 |
| 6.148e-05 | -9.70 | WDTC1 (WD and tetratricopeptide repeats 1) | protein interactions | 23038 | 143 | 62 | 19454 | 5460 |
CCNF,TXNDC12,MAD2L2,PPP5C,CUL3,COPS7A,PNOC,PCCB,FBXW11,CCT2,PFDN6,PFDN4,PFDN2,BAP1,TXNL1,UNC45A,FUT8,ATG16L1,ZCCHC17,MED23,PIH1D1,ACACA,PDCL,AIP,COPS2,NAA30,EED,DECR2,TRMT10B,TCP1,COPS7B,CCT7,HSP90AB1,CGGBP1,CACYBP,PXYLP1,USP3,ANKMY2,PFDN5,PDIA3,NT5C2,XPO1,COPS5,FKBP4,MED4,DNAJC7,BCKDK,PC,MRPS11,SRSF7,RUVBL2,TTC4,SOCS2,PRELP,CCT5,KBTBD4,PLA2G12A,NUDCD3,SERPINB11,UCK2,CHMP4C,MSRB3 |
| 6.148e-05 | -9.70 | EPHA5 (EPH receptor A5) | protein interactions | 2044 | 143 | 62 | 19454 | 5460 |
FTSJ1,PIK3R2,HADHA,BANF1,SEPTIN6,LIN7C,ARCN1,PICALM,JUP,VAPB,ATP5PO,PAK2,SLC22A8,NTPCR,CDC42,NOTCH2,USP6NL,EFNA5,GNB1,MB21D2,SMAP2,GAB1,FAM91A1,EPHA2,SLC38A1,RHOB,MYO6,GORASP2,PIK3R3,PTPN11,PKP4,NIBAN2,POLDIP3,DUSP21,SLC39A7,DLG1,TSPAN3,HGS,NUDT19,TRAF2,SNAP29,FCHO2,SNX2,OCRL,CDCA3,RAC2,SEC23A,NRSN1,EHBP1,PTPN1,EFNA3,TNIK,WDR6,TRAPPC4,NCK1,SHC1,ESYT1,NOS1AP,CDK5RAP3,RHOG,CTNNB1,PIK3R1 |
| 6.148e-05 | -9.70 | AARS1 (alanyl-tRNA synthetase 1) | protein interactions | 16 | 143 | 62 | 19454 | 5460 |
CHMP4C,EZH2,MAP1LC3B,TP53,TPD52,RIGI,KRAS,HSD17B10,EMC2,ABCE1,AGR2,PPM1B,FKBP4,YWHAG,ATG7,ANKMY2,PDIA3,MOV10,HSP90AB1,IAH1,CACYBP,SUMO2,PRNP,GJA1,ACTA2,EEF1B2,PIH1D1,UBE2M,RPA2,NEK7,CFTR,CDC42,SAP18,FBXW7,EMC1,SQSTM1,SIRT7,BAP1,RPA3,SOD1,CALU,RIT1,HSP90AA1,BRCA1,SPOP,NIF3L1,CDKN3,SFN,CUL3,MYC,VIRMA,ESR2,TOM1L1,FBXO22,STAT1,KCTD9,PPP2R5E,EIF4A3,ENO1,LMBR1L,OPTN,CCNF |
| 6.155e-05 | -9.70 | RER1 (retention in endoplasmic reticulum sorting receptor 1) | protein interactions | 11079 | 163 | 69 | 19454 | 5460 |
TSPAN5,GOSR1,HSCB,EMC1,GFM1,SLC35F2,TMEM185A,VIPR1,SYVN1,RABAC1,RPA3,CAV2,HBB,SIGMAR1,HSP90B1,ATP5PO,RPA2,SEC62,YIPF5,SEC22B,PGRMC1,ATG16L1,ESR2,SYNGR1,SLC11A2,DPEP1,LMBR1L,VDAC2,CCNF,OAT,SCFD1,ENDOD1,ATP1A3,GORASP2,ATP5F1A,RAB2A,SYCE3,TMED7,SRPRB,TMEM33,KRAS,TMX3,RAB1A,CCR1,STX12,CRELD1,SCAND1,AQP3,PPIF,ETFB,CCDC47,RAF1,UBL4A,ATP5PD,TMED9,LDLR,CYB5A,CD274,OSBPL8,UPK1A,TST,RHOG,FAM241A,CCR6,LAMP3,ATP5MG,COX5A,PMP22,RAB5C |
| 6.167e-05 | -9.69 | MRPL53 (mitochondrial ribosomal protein L53) | protein interactions | 116540 | 192 | 79 | 19454 | 5460 |
MRPL34,GFM1,NGRN,RPS28,EXD2,STX7,MRPL20,HSCB,MRPL17,MRPL41,MRPL57,MRPL40,MRPL10,MRPL12,SPR,MTRES1,MRPS18A,MRPS28,MRPL13,UBE2I,TACO1,MTG1,CCDC90B,UBE2L3,MRPL23,TAX1BP1,SNX3,MRPL16,TUFM,AUH,SUGP1,MYC,PMPCA,DNAJC19,UBE2H,RBM27,HINT2,ZC3H11A,HSPD1,MRPL52,LSM14A,PQBP1,MEPCE,FASTKD5,MRPL22,PAX6,PPIF,AURKAIP1,METTL15,KIF2A,THAP1,UBL4A,MRPL47,MRPL11,MRPL33,SMARCB1,GFM2,MRPL49,MRPL51,NDUFS3,PCBP4,RFX5,GATD3,THY1,SSBP1,DBT,MALSU1,MRPL24,MRPL50,MRPL9,PPIB,GRSF1,MTRF1,BABAM1,SSX2IP,MRPS26,MRPL18,CHCHD1,SNRNP70 |
| 6.167e-05 | -9.69 | COX2 (cytochrome c oxidase subunit II) | protein interactions | 4513 | 192 | 79 | 19454 | 5460 |
COX6C,RPA2,METTL14,HSP90B1,STOM,SSR1,GRM2,CYC1,SLC25A3,TOMM22,UQCRC1,PDHB,PHB2,SLC25A51,HSPA5,BCL6,RPA3,HSPB2,HADHA,GFM1,PMAIP1,COX16,MYC,AKT1,RALB,PMPCA,TOMM40,ATP5F1B,MGST3,ACTB,UQCRQ,ESR2,VIRMA,LMBR1L,UQCRC2,VDAC2,CCDC90B,RPN1,EZH2,GPD2,PDHA1,NDUFS3,ATP5PB,PREB,RAF1,PPP2R1A,APOO,FAF2,PSMA1,TRIM37,VDAC1,COX7B,RAD21,SFXN1,NDUFA4,HINT2,COX8A,POR,TMEM70,SMDT1,CALR,DPP4,COX5A,NDUFV2,CTNNB1,RAB1B,MYL12A,NDUFS8,COX14,RMND1,SLC25A12,SDHB,AIFM1,COX7A1,COX4I1,PHB1,CORO1C,COX20,GATD3 |
| 6.215e-05 | -9.69 | KIF26B (kinesin family member 26B) | protein interactions | 55083 | 49 | 27 | 19454 | 5460 |
CDK1,CASK,ASB8,WBP11,CDC42,MX1,TRAF2,RND2,CBLL1,DLG1,LIN7C,CDK5,YWHAZ,RHOB,RHOG,YWHAB,SFN,LIN7B,YWHAG,YWHAH,RHOH,PRNP,SPPL3,VIRMA,RAC2,CDK6,GSK3A |
| 6.220e-05 | -9.69 | HBS1L (HBS1 like translational GTPase) | protein interactions | 10767 | 115 | 52 | 19454 | 5460 |
SLC31A1,STAU1,RPA3,CXCR4,PML,EXOSC4,EP300,RPA2,HECTD1,FAXC,GPX1,SRPK2,APEX1,CCNF,PELO,GSK3A,DTYMK,RPS20,FAS,BICD2,EXOSC1,RPS5,RBM7,MYC,CUL3,PSMD1,ISCA2,PTGES3,CPLX1,EIF1AD,LIPA,EXOSC3,TP53,GCHFR,TULP3,MSX2,EXOSC8,RPS16,RAB39B,EGLN3,CEP19,SURF6,AIFM1,UBE2G2,EIF4E2,SKIC8,MPHOSPH6,LAMP3,XPO1,COPS5,DDRGK1,DIS3L |
| 6.220e-05 | -9.69 | SSMEM1 (serine rich single-pass membrane protein 1) | protein interactions | 136263 | 115 | 52 | 19454 | 5460 |
PLPP6,LEPROTL1,TMEM60,TNF,SEC11A,ERG28,RUSF1,STX8,CTSA,AQP3,TMEM45A,MFSD6,NRM,TP53,PGAP2,CSNK1E,TMEM97,CXCL9,MFSD5,TMEM14A,DEFB121,SLC35A1,SLC41A1,FATE1,SLC38A7,PLPP4,TLCD1,TMEM243,TMEM203,HSPA8,SLC39A9,JAGN1,SLC35E3,FAM3C,CSNK1A1,CMTM7,STOM,BET1,BLCAP,EFNA5,SMAD5,CLRN2,SPCS1,CYBC1,CDIPT,SLC38A1,PDF,ENDOD1,CYB561,HMOX2,CSGALNACT2,GJB2 |
| 6.223e-05 | -9.68 | RNF26 (ring finger protein 26) | protein interactions | 79102 | 59 | 31 | 19454 | 5460 |
PSME1,TMED1,SPECC1L,SQSTM1,TMEM33,TOLLIP,UBE2D3,RNF26,PDE2A,MTX2,UBE2W,ETF1,RAB6A,FAF2,SAMM50,STOM,UBE2G2,CYB5R3,PSME2,EIF2S2,TAX1BP1,RAB1B,NAA50,RAB2A,CALR,ENDOD1,UBE2D1,BLVRA,USP15,ZMPSTE24,CA2 |
| 6.245e-05 | -9.68 | RSRC1 (arginine and serine rich coiled-coil 1) | protein interactions | 51319 | 104 | 48 | 19454 | 5460 |
DHX9,PQBP1,GLUL,SSRP1,SNRPG,TSSC4,EEF1A1,CD2BP2,RAF1,SNRPE,AAMP,HDAC11,FOLR1,DKC1,COMMD6,HNRNPL,SPPL3,ACTR3B,YWHAG,CSNK2A1,XPO1,UQCR11,SNRNP70,DDX23,COMMD2,EXOSC4,SF3B1,RPA3,DVL2,LUM,SNRPA,NHP2,POLR1D,UBA52,ATG16L1,TFIP11,VPS18,LSM2,RPA2,CSNK2B,SRPK2,IFI6,SNRNP40,RACGAP1,SNRPB,PAPOLA,CFAP20,UBE2H |
| 6.258e-05 | -9.68 | U2 snRNP | cellular component | GO:0005686 | 25 | 17 | 19108 | 5553 |
SF3B1,SNRPN,SNRPG,SF3A1,SNRPE,SF3B5,SF3B4,SNRPB2,SNRPD2,SF3B6,SNRPD3,DDX46,SNRPB,SNIP1,SNRPA1,RBMX2,SNRPD1 |
| 6.266e-05 | -9.68 | PYCR1 (pyrroline-5-carboxylate reductase 1) | protein interactions | 5831 | 195 | 80 | 19454 | 5460 |
MTRES1,PIH1D1,CD46,DUSP14,ATG16L1,PAFAH1B1,CRYZ,HSCB,UCHL3,NPTN,FBXW7,HNRNPH2,HSPA8,ANAPC16,GFM1,LCA5,NGRN,BAP1,PEBP1,IDH3A,EXD2,ANAPC4,COP1,HTRA2,BRCA1,DEPDC1B,BAG3,CDC16,AUH,MYC,MTG2,CREBBP,CUL3,PYCR2,PMPCA,VIRMA,PARL,ARMC6,SMU1,ANAPC2,TACO1,CCDC90B,GFM2,EZH2,PDHA1,AURKAIP1,TNPO2,METTL15,RAF1,CCDC47,E2F4,MRPL11,FASTKD5,PRDX4,MDC1,SEPHS1,IMMP2L,G3BP1,CDK2AP2,HINT2,COX8A,NUDT5,HSPD1,SFXN1,HNRNPD,CDC23,MRPS26,RHOG,CHCHD1,GRSF1,MTRF1,COX14,RMND1,FZR1,GATD3,AIFM1,CD274,SSBP1,COX4I1,ARMC1 |
| 6.271e-05 | -9.68 | PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) | protein interactions | 5300 | 373 | 139 | 19454 | 5460 |
TFPT,HINT1,TAGLN3,DYNC1I1,THRAP3,HNRNPK,HSPE1,VPS16,TP53,MLLT6,SOCS3,UBXN2B,CHAMP1,NHERF1,TBC1D4,ETV6,PTPN1,SMAD3,MCL1,RB1,SELENOV,RPL35A,CDK9,ZBTB2,GRSF1,TLE1,CSNK2A1,SSBP4,PKIB,CDK12,SOD1,IRF3,PML,GPX4,HDAC3,PPP1R2,FBXW7,RPL4,BCL6,AATF,ATG16L1,SPR,CCND1,NEK2,SNRNP27,RPRD1B,CDK1,BTG2,CARHSP1,LEPR,CCNF,HEXIM2,TRIM27,CSNK2B,SNX12,GSK3A,JAKMIP2,SNX3,GABPA,UBB,TRAF1,VIRMA,DDAH2,CCNB1,CFL1,NONO,CHPF,AR,EIF3G,BICD2,NCKIPSD,AP2A1,FKBP1B,SMAD2,UBE2H,MAP3K11,GPAA1,PABPC1,G3BP1,KRAS,ZBTB14,UBE2A,DMPK,TFG,PAX6,FASLG,RAF1,SUPT5H,E2F4,JUN,TRAF2,GTF2E2,ZNF526,RAB4A,POLR2D,SSBP3,FABP5,DUSP6,PPIA,NUP35,CEP19,STK3,DHX15,MDFI,INO80E,ZCCHC10,MAP1S,CPEB1,CTNNB1,CDKN1B,NAB2,FOS,CCDC184,GPHN,HADHA,DDX5,EP300,FOXP2,G3BP2,NUP62,SSBP2,PPARG,FKBP1A,ZBTB42,PNMA1,CCDC90B,NFKBIA,RNF208,ATP5F1B,TAGLN2,LRIF1,MYC,HNRNPC,THAP7,RBBP8,CYP1A1,BRCA1,SP1,OSGEP |
| 6.272e-05 | -9.68 | cytochrome complex | cellular component | GO:0070069 | 36 | 22 | 19108 | 5553 |
COX5A,COX7B2,COX8A,COX10,COX7B,NDUFA4,COX4I1,UQCRC2,UGT1A1,UQCRH,COX6A2,BCS1L,UQCR11,COX7A1,UQCC3,COX6B1,COX4I2,COX6B2,UQCRQ,CYC1,UQCRC1,COX6C |
| 6.307e-05 | -9.67 | regulation of ERK1 and ERK2 cascade | biological process | GO:0070372 | 295 | 118 | 18204 | 5365 |
HMGB1,SYK,MIR205,PDE8A,PTPN22,EPHA2,IL1B,ATF3,EMILIN1,FBXW7,PRMT5,DUSP26,ZDHHC17,CCR7,PYCARD,MIR23A,HRAS,AGER,HAND2,SMAD4,DUSP10,ALKAL1,IGF1,NOTCH2,SPRED1,ADIPOQ,TNF,ACTA2,CRYBA1,DUSP3,CX3CL1,IL1A,MIR24-1,RAP1A,MIR145,GSTP1,SPRED2,MT3,PHB1,PRKCA,DDR1,CCL21,GNAI2,MIRLET7B,CCL19,MIR221,DLG1,CRKL,NHERF1,NPSR1,MIR200C,CHI3L1,NLRP6,DUSP6,FGF1,PLA2G5,TIRAP,NRP1,RAMP3,SHC1,CCR1,MAP2K1,TBC1D10C,MIR424,NPY5R,RAP1B,P2RY1,ACKR3,CCL3,MIF,ADRA1A,SRC,HTR2A,DDT,PTPN1,ANGPT1,PHB2,SPRY1,BTN2A2,PTPN11,MAP3K12,OPRM1,OR2AT4,TRAF7,TLR4,MIR133B,DNAJC27,TIAM1,ICAM1,AKAP12,EPHA4,MIR185,FERMT2,FLCN,CSK,MIR126,SYNJ2BP,TLR9,CNKSR3,GPNMB,YWHAZ,GLIPR2,TNFAIP8L3,NTRK3,LMO3,NTRK2,MIR503,CD4,MIR21,MIR519D,TPBG,EPO,GPBAR1,FGF23,DSTYK,SEMA7A,CD36,CHRNA7 |
| 6.321e-05 | -9.67 | SLC38A2 (solute carrier family 38 member 2) | protein interactions | 54407 | 129 | 57 | 19454 | 5460 |
KRAS,TOLLIP,RAB3B,STX11,SAR1B,FLOT1,TMT1A,COX8A,RPN1,RAB4A,CCDC47,TP53,LPAR6,ARF6,RHOH,STX6,LMAN1,DIRAS3,CAV1,TMEM237,RAB35,HRAS,HSD17B11,GJA1,RAC2,RHOG,LAMP2,COX5A,RAB5C,YWHAG,LAMP3,YWHAH,STX7,TSPAN5,RHOU,RPA3,DERL1,RAB9A,SQSTM1,RAB5A,RPA2,BET1,CDC42,SEC62,OTULINL,RND2,RHOJ,ATP6AP2,VIRMA,LMBR1L,SEC61B,LAMTOR1,RHOB,RAB2A,RAB11A,GJB2,DNAJC5 |
| 6.321e-05 | -9.67 | GUK1 (guanylate kinase 1) | protein interactions | 2987 | 54 | 29 | 19454 | 5460 |
LAP3,GABARAPL2,GLRX5,NUDT19,MSRB3,NDUFA4,TCOF1,PRDX6,HSD17B10,HINT1,SRI,KRAS,PMPCA,COX5A,GSTK1,MOV10,ISCA2,MTPN,AK2,FXN,HNRNPD,BAX,FAHD1,TXNDC12,LYRM2,TXN,CLIC4,TMEM97,ESD |
| 6.321e-05 | -9.67 | TICAM1 (TIR domain containing adaptor molecule 1) | protein interactions | 148022 | 54 | 29 | 19454 | 5460 |
XPO1,TRIM8,TNFAIP3,TRAF6,TRAF1,KCTD10,RNF144B,GPX1,TRAF2,TRAM1,TIRAP,AZI2,TANK,SYK,TBK1,PIK3CA,TLR3,MAVS,TLR2,IRF3,ABCF1,INPPL1,TLR4,RIGI,TICAM1,TICAM2,SRSF4,IRF7,PELI1 |
| 6.329e-05 | -9.67 | ATP13A1 (ATPase 13A1) | protein interactions | 57130 | 166 | 70 | 19454 | 5460 |
ARF6,BUD31,TLCD4,NUP35,TMEM237,HSD17B11,VCPIP1,RB1CC1,LAMP2,TSPAN10,RAB5C,CCR6,LRRTM1,LAMP3,TMBIM6,FAM241A,SLC7A14,RIGI,CYP2C9,SNIP1,TMT1A,CD83,LPAR2,EMC2,RPN1,DISC1,TMEM14B,CCDC47,TOP3B,RAF1,IL1R2,ISG15,DNAJC25,MMD,APEX1,SEC63,RNASEK,ESR2,LMBR1L,CCNF,ELOVL4,CYB5R3,TNFRSF9,SYNGR1,SEC61B,CD226,TYROBP,MFSD14B,RIT1,GABRG2,GPBAR1,SCN3B,RUNX1,EMC1,PXMP2,COIL,CD40,RPA3,TSPAN15,APPBP2,DERL1,LMNA,RPA2,SSR1,MANBAL,TPRA1,PGRMC1,SEC62,OTULINL,DIO3 |
| 6.359e-05 | -9.66 | PDXDC1 (pyridoxal dependent decarboxylase domain containing 1) | protein interactions | 23042 | 198 | 81 | 19454 | 5460 |
BET1,OTULINL,RND2,CDC42,RFXANK,DUSP22,CFTR,CDK7,FGFR1,RPA3,SLC39A9,CXCR4,SLC22A6,RAB5A,RAB9A,DCTN3,SLC15A1,PHB2,NSFL1C,PXMP2,STX7,SLC5A6,RAB2A,GPR17,RAB11A,GGH,FAS,LAMTOR1,NTRK3,EPHA2,HTRA2,ARF1,LMBR1L,CHRM4,NFKBIB,TMEM108,TAX1BP1,APLNR,VIRMA,LPAR6,TFRC,PTRH2,RAB4A,AQP3,MAD2L1BP,RND3,DDR1,TMT1A,EFNB1,NTRK2,BCAP29,VPS26B,TRIM11,CD80,KRAS,RAB3B,ARF4,SAR1B,DPP4,LAMP2,UBXN6,GSTM3,FAM174A,P2RY10,LAMP3,RPAIN,SMAD4,SLC2A1,RHOG,AGR2,STYK1,RAB35,EEF1AKMT3,GJA1,RAC2,ARL4D,TRIM35,STX6,WDR44,CAV1,OPRL1 |
| 6.453e-05 | -9.65 | ABC-family proteins mediated transport | REACTOME pathways | R-HSA-382556 | 107 | 53 | 10285 | 3229 |
PEX3,PSMD1,PSMB2,ABCC2,PSMA6,RNASEL,DERL1,ERLIN1,PSMC1,CFTR,PSMD12,ABCF1,PSMC3,EIF2S1,ABCB1,PSMA1,RPS27A,ERLIN2,PSMD4,PSME2,PSMB4,PSMD6,SEM1,PSMB9,ABCE1,PSMA4,PSMA5,PSMB10,EIF2S2,PSMB11,PSMC5,PSMB6,PSMA2,PSMB3,PSMB7,PSMD3,ABCC5,PSMB1,OS9,PSMB5,PSMA3,PSMC4,ABCB9,ERLEC1,PSMD14,DERL2,RNF5,UBA52,UBB,PSMD10,KCNJ11,PSME1,PSMD7 |
| 6.497e-05 | -9.64 | TIMM13 (translocase of inner mitochondrial membrane 13) | protein interactions | 26517 | 169 | 71 | 19454 | 5460 |
YBEY,ETV6,AIFM1,TIMM8B,COX4I1,EGLN3,COX14,NUP35,PLGRKT,SLC25A12,CPNE1,CAND1,MIF,BCL7C,DDRGK1,MAP3K14,RASSF8,PDYN,TST,DICER1,TUBG1,RHOG,SNRNP70,RPL24,CLPB,SFXN1,BCKDK,HNRNPA2B1,SOCS2,STRADB,PCGF6,IMMP2L,KRAS,CDK20,APOO,AURKAIP1,TIMM8A,OARD1,ILF2,CAPZA2,CAB39,MOB4,SF3B4,ALB,PARL,LYZL6,MGST3,MATR3,PSMD6,MYC,CUL2,CUL3,ANAPC4,PIM2,HTRA2,RIT1,YWHAZ,RC3H2,SF3B1,SNRPA,BAP1,LCA5,SOD1,RPA3,HSPA5,PHB2,SLC25A51,TIMM10,COQ8B,LMNA,PPT1 |
| 6.532e-05 | -9.64 | response to chemokine | biological process | GO:1990868 | 92 | 45 | 18204 | 5365 |
XCL1,CX3CL1,CCL5,CXCL8,CCL2,CCR3,CXCL9,CXCL10,DUSP1,CXCL11,CCL24,GPR35,CCL4L1,GPR17,GPR75,WBP1L,CCR1,CX3CR1,CCL17,CCL18,CXCR1,SLC12A2,CCL23,CCL1,CXCL12,CCL25,CCR5,CCL21,CCL3,CXCR6,CCR4,ACKR3,CXCR3,CXCL3,CCL20,CXCL1,CXCR4,CCL19,CCR7,CCR2,CCL8,CXCL13,OXSR1,CCL11,CCR6 |
| 6.532e-05 | -9.64 | cellular response to chemokine | biological process | GO:1990869 | 92 | 45 | 18204 | 5365 |
CCL2,CCL5,CXCL8,CXCL10,CXCL9,CCR3,XCL1,CX3CL1,CX3CR1,CCR1,WBP1L,CCL18,CCL17,DUSP1,GPR75,GPR17,CCL4L1,GPR35,CXCL11,CCL24,CCR4,CXCR6,CCL3,CCL21,CXCR3,ACKR3,CCL1,CCL23,SLC12A2,CXCR1,CCR5,CCL25,CXCL12,CCL8,CCR2,CCR7,CCL19,CXCR4,CCR6,CCL11,OXSR1,CXCL13,CXCL3,CXCL1,CCL20 |
| 6.589e-05 | -9.63 | CAST (calpastatin) | protein interactions | 831 | 96 | 45 | 19454 | 5460 |
STAU1,RPA3,BAP1,PSMB7,PCLAF,STX17,RARS1,PIH1D1,PSMB3,CAPN1,CFTR,VIRMA,CCNF,PSMA6,CKB,UBE2H,CSK,NONO,PSMA5,COPS4,PABPC1,HNRNPA2B1,PLS3,PTRH2,PPFIA2,CAPN2,PPME1,SART3,TBK1,RAF1,FNTB,FZR1,HNRNPL,PRNP,SUMO2,HTRA1,SNRPD3,HSP90AB1,CCT7,PSMB5,PPFIA3,HSPB1,PDIA3,GSTM3,COPS5 |
| 6.610e-05 | -9.62 | ILK (integrin linked kinase) | protein interactions | 3611 | 312 | 119 | 19454 | 5460 |
GGT7,RAN,POLR2B,PPP5C,ACAP2,ERH,APEX1,ATP5F1B,CYP26A1,MTM1,BTF3,MYC,CUL3,HSP90AA1,ILK,CCT2,CKB,BRCA1,LMNB1,HSPA8,DDX5,ATP5MK,ITGAV,TOMM22,ADNP,SPINT2,SIN3A,WDR6,CACYBP,EGLN3,HSP90AB1,DHX15,CCT7,TCP1,SUMO2,XPO1,ACP6,CTNNB1,STOML2,HAX1,HSPB1,FKBP4,RUVBL2,PRPSAP1,EWSR1,BAG2,CCT8,NDUFA4,IMMP2L,RBBP7,LASP1,HNRNPF,RUVBL1,SOX2,KIF2A,RAF1,RPN1,UCK2,SEC61A1,TRIM27,CDIPT,CCNF,STUB1,CTNNA1,TMSB4X,TECR,FERMT2,PPAT,RHOJ,ATP5F1A,CTSD,AKT1,SLC25A1,CSK,PTPN11,IGF2BP1,ATP1A1,CALU,RPA3,UGP2,MARS1,FBXW7,CDC42,CNP,LIMS2,ACACA,SDCBP,LMNA,RPA2,PICALM,SSR1,SLC12A2,AIFM1,SSBP1,AIP,ALYREF,ILVBL,CAV1,PRNP,CGAS,COPS5,ELOC,MOV10,AKAP8L,NPR2,SLC2A1,SHC1,SLC16A1,ABCE1,TRAFD1,FAF1,SLC25A10,PPP1R12A,FKBP8,PTGES3,CCDC47,CCT5,TMEM165,NDUFS3 |
| 6.625e-05 | -9.62 | NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8) | protein interactions | 4714 | 118 | 53 | 19454 | 5460 |
ATP1A1,PIM2,HMOX2,TOMM40,NDUFAF2,NDUFB7,PARL,UQCRQ,ATP5F1B,IL2RA,CCDC90B,UQCRC2,SLC25A3,EIF2B3,SSR1,SAMM50,VAPB,UQCRC1,TPT1,TIMMDC1,PHB2,HSCB,HADHA,NDUFC2,TACR1,TMEM70,POR,NDUFV2,ATP5MG,NDUFS8,LMAN1,HNRNPL,RPL35A,XXYLT1,NDUFA1,FUT1,CORO1C,COX4I1,GPR34,NDUFA12,CRELD1,NDUFS3,AQP3,NDUFS6,RPN1,YIPF3,APOO,MTCH2,DNAJC30,EMC2,NDUFA4,NDUFB5,RAB1A |
| 6.625e-05 | -9.62 | CACTIN (cactin, spliceosome C complex subunit) | protein interactions | 58509 | 118 | 53 | 19454 | 5460 |
MRPL22,DPM2,KRAS,CHCHD2,H3C1,ZC3H11A,TMEM14B,CBX3,EZH2,NECAP1,CHMP4C,H2AJ,RAF1,JPH4,PRPF18,PTP4A3,CDC5L,SPTAN1,COPS2,DNAJC4,ANKRD50,UQCR11,DDX23,CSNK2A1,XPO1,GTF2E1,DDX50,ZCCHC10,COIL,ACER3,EXOSC4,RPA3,NKAPD1,LMNA,ATG16L1,SUMO1,APEX1,TNPO3,ESR2,SRPK2,RNASEH1,SNRNP40,PSMD6,IFI6,CSNK2B,EIF4A3,PELO,EZH1,HSP90AA1,UBE2H,RC3H2,BTF3,MYC |
| 6.643e-05 | -9.62 | FASTKD3 (FAST kinase domains 3) | protein interactions | 79072 | 132 | 58 | 19454 | 5460 |
MRPS25,MRPS16,PYCR1,HNRNPAB,PYCR2,NDUFAF4,DLST,TACO1,MRPL53,MRPS28,MRPS34,NDUFA5,AGTRAP,MRPL12,HCST,NPY2R,MRPL41,NDUFS2,NME4,MRPS7,CXCR4,TNFSF13,MRPS26,MRPS35,GRSF1,NDUFV2,P2RY10,MRPL9,LAMP3,MRPL50,AGK,MRPL24,MRPS23,NDUFS8,DBT,MRPS9,NDUFS3,NDUFS6,PDHA1,MRPL49,NDUFA12,ETFB,NDUFA2,MRPL47,PPIF,KGD4,ETFA,CD80,MRPS33,HNRNPDL,SIAE,ABHD10,MRPS18C,MRPS17,HSPD1,OSTM1,MRPS11,MRPS18B |
| 6.659e-05 | -9.62 | MYO5A (myosin VA) | protein interactions | 4644 | 172 | 72 | 19454 | 5460 |
NEK2,PPP1CB,MYL12B,ATG16L1,STX7,TRIM52,FBXW7,STAU1,RAB9A,SQSTM1,SIRT7,TRIM3,GRIA2,FOS,RHOU,BAP1,LAMTOR1,AR,USP14,DNAJC5,BTF3,PDE4B,RAB11A,MYC,RAB2A,CREB3,APEX1,ESR2,VIRMA,SH3BGRL,DYNLL1,TMOD3,DKK3,MOB4,LURAP1,CTTN,GRIA1,HGS,RHOBTB1,NUPR1,RND3,NEFL,CAPZA2,PNMA2,RAB4A,PLS3,EZH2,EXOC3,ISG15,DPM2,FBXO25,TRIM37,RAB3B,TNF,RAB27A,RAB3A,PEX3,EID1,LAMP3,HDAC6,ZCCHC10,LAMP2,OS9,FHIP1B,CDK9,PTP4A3,RHOH,CGAS,EIF2B5,HNRNPL,FEZ1,RAB35 |
| 6.659e-05 | -9.62 | DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease) | protein interactions | 22894 | 172 | 72 | 19454 | 5460 |
KRAS,SOCS2,RIGI,SEPHS1,SCYL2,CDK5,SEPTIN7,EXOSC3,SH3GLB1,RNF126,SSBP3,CD14,TP53,EXOSC8,GTF2E2,TULP3,TRIM35,PRNP,NTMT1,WIF1,SURF6,CD274,EEF1AKMT3,PRCC,PHB1,TES,MED29,KPNA1,MPHOSPH6,DRG1,UBXN6,BABAM1,DDRGK1,HSCB,STAU1,FBXW7,BMPR1A,RBM23,RPA3,SIRT7,PML,HSPA8,EXOSC4,DCTN3,C1D,EP300,PALS2,LMNA,RPA2,RNF103,ATG16L1,RFXANK,SNRNP27,ZNF428,DUSP22,ZBTB17,MED17,PPP5C,RAN,CHORDC1,TXNIP,CYP1A1,OSGEP,EXOSC1,DNAJB6,RIT1,UBE2H,MYC,SUB1,CUL3,MTPN,GGH |
| 6.740e-05 | -9.60 | RPP30 (ribonuclease P/MRP subunit p30) | protein interactions | 10556 | 107 | 49 | 19454 | 5460 |
MEPCE,KRAS,HUWE1,POP5,SOX2,RAF1,MOB3C,MAGEA4,PSMB1,PHB1,SURF6,HMG20A,WDR44,FZR1,CAND1,RPS16,DDRGK1,ATG7,IFI16,SNRNP70,RPA3,INPPL1,RPP14,STAU1,NPM3,UFL1,RPP21,HEXIM1,RPA2,PTEN,PSMA6,POP7,CCNF,MAD2L2,ESR2,RPP25,RPP25L,MLF2,DNAJC8,CUL3,MYC,CALU,DNAJB6,THTPA,UBE2H,RIT1,H1-10,ATG3,PSMD14 |
| 6.740e-05 | -9.60 | BCS1L (BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone) | protein interactions | 617 | 107 | 49 | 19454 | 5460 |
MTG1,CCDC90B,TACO1,SAYSD1,RIT1,NRP1,PMPCA,MTG2,AUH,TUFM,MBLAC2,LITAF,HSCB,CRYZ,EXD2,RPA3,MTDH,GFM1,RPA2,MTRES1,RBFOX2,MRPL10,MX1,AIFM1,SSBP1,GATD3,CHCHD1,RHOG,BRD3,MRPS26,VPS26A,GRSF1,MDFI,MTRF1,DNAJC30,CD80,KRAS,IMMP2L,MATN4,FASTKD5,HSPD1,COX8A,HINT2,PDHA1,UCKL1,CRELD1,GFM2,MRPL11,METTL15 |
| 6.740e-05 | -9.60 | SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1) | protein interactions | 6599 | 355 | 133 | 19454 | 5460 |
EZH2,RBPJ,SMARCB1,MTA2,MOB3C,TAF10,RHOBTB1,RAF1,E2F4,SOX2,JUN,MSX2,SAP30,RBBP7,ASF1A,RUVBL1,PAX6,SSRP1,PLSCR1,BCL7B,TOP2B,EWSR1,HNRNPD,LHX2,BAZ1B,HMGA1,IFI16,WWP2,RAB5C,BCL7C,SPTAN1,NUP35,SIN3A,FUBP3,SRSF1,EED,BRD9,PPARG,GSTO2,ACTL6A,STAU1,SAP18,HIRA,SMARCD3,DDX39B,FOS,DDIT3,EP300,LMNB1,BRCA1,SP1,SLC15A2,CREBBP,HNF1B,MYC,HNRNPC,CUL3,SMARCE1,CPSF2,DRAP1,STAT2,ACTB,SNRNP40,RBBP4,APEX1,TNPO3,RAN,KRTAP3-1,PRMT5,GTF2F1,MCPH1,CDK8,TP53,H2AX,EGR2,ZNF581,MAP1LC3B,ING1,SOX9,KPNA2,MEPCE,MSH6,MDC1,PPP1R12A,SMAD4,SNRNP70,DNAJC7,USP15,BRD3,CIDEB,MOV10,HDAC6,GTF2E1,FZR1,KLF1,CAND1,TOP1,H2AZ1,SMAD3,DCTN4,HSP90B1,GRM2,E2F6,HEXIM1,ATG16L1,SF3A1,CCNH,KDM1A,SMC4,NUCKS1,MBD3,SS18,SIRT7,RC3H2,STK11,SMAD2,SMARCA5,AKT1,RUNX1,AR,NONO,MGAT5B,TMOD3,DEK,NMI,VIRMA,UFSP1,CCNF,TUBA1B,UBN1,ZNF330,ING2,MACROH2A1 |
| 6.744e-05 | -9.60 | NSA2 (NSA2 ribosome biogenesis factor) | protein interactions | 10412 | 213 | 86 | 19454 | 5460 |
NOP53,CCDC86,HSH2D,H1-5,RPL35,RPL19,ESR2,RPL37A,FTSJ3,MRPS25,ZCRB1,LMNB1,H1-1,AUH,MYC,ZNF668,KRAS,RPL28,SRSF4,UBE2A,FGF3,TYW5,RPL31,RTCB,RPL18,SART3,RAF1,MAK16,LYAR,SPTAN1,RPL7,RPS10,CNTROB,SRSF1,MRTO4,RPL8,IFI16,DDRGK1,RPL4,DGCR8,NPM3,BRIX1,UTP23,SIRT7,NLE1,RPL27,RPA3,RPA2,MACROH2A2,ZNF574,RPL26L1,RPLP0,RPS14,FGF13,RPL13A,RSL24D1,SRPK2,EIF2AK2,CCNF,EIF2S2,PRKRA,RPL7A,RPF2,RPL26,RPL17,RPL23A,RPL3,RBM34,NUPR1,RPL15,APOBEC3D,CGAS,PRNP,FZR1,RPS16,ZBTB2,SURF6,KRR1,RPL32,SRP14,MRPS9,CD9,RPL10A,RPS2,NOL12,E4F1 |
| 6.747e-05 | -9.60 | negative regulation of response to external stimulus | biological process | GO:0032102 | 428 | 163 | 18204 | 5365 |
CLEC12B,MIR20A,GHRL,THBD,IL22,NDFIP1,CTNNA2,STAT2,MIR222,SLC12A2,EIF4E2,NLRP3,FAM3A,TNR,IL2,F2,AIF1,MIR221,DPP4,CLDN3,KLRD1,BANF1,SOD1,TRIB1,RNF26,CCL2,PTEN,NLRP6,CD200R1,IL2RA,NRP1,MIR187,MIR105-1,ACP5,NR1H2,TMSB4X,DRD1,MIR16-1,NFKB1,MIR141,ARG2,NPY5R,OAS1,RB1,RGMA,MIR488,MIR424,DEFB114,FEM1A,SYK,MIR205,SPP1,OTULIN,TRAFD1,HDAC6,FCGR2B,ISG15,NFKBIL1,SEMA5A,SELENOS,DUSP10,PSMA1,DRD3,STAP1,GREM1,PLG,ADTRP,SLC6A3,TNF,ADIPOQ,NT5C2,IGF1,IL10,MUL1,CERS2,SMAD3,MIR1298,DUSP3,MIR145,MIR920,GSTP1,CCN3,TNFAIP3,GPX1,LACRT,DUSP1,YES1,IL20RB,SOCS5,TNFRSF1B,MIR31,YWHAZ,PROS1,IL4,TNFAIP8L2,SFN,PPARG,LILRA2,MIR149,IFI16,CXCL13,MIR146A,PTGER4,MIR21,CD9,LPCAT3,C1QTNF1,SOCS3,LYAR,NMI,CNOT7,PPM1B,FURIN,MAVS,MIR204,MIR181C,SERPINB9,MIRLET7G,MIR195,YTHDF2,UBASH3B,SAMHD1,MIR26B,MIF,PRDX2,MMP28,PSMB4,LILRB1,FOXP3,SRC,ADORA1,DDT,LDLR,MIR590,BACE1,FGL2,USP15,MICB,TFPI,KLF4,CD200,PPARA,TRIM21,MIR223,MACIR,CASK,IL12B,ST6GAL1,FGR,EPHA4,MIR126,IER3,NEO1,TNFAIP6,TRIM45,USP38,MIR142,PADI2,MIR15A,IL13,GPR17,MIR34A,PYDC2 |
| 6.751e-05 | -9.60 | PPIB (peptidylprolyl isomerase B) | protein interactions | 5479 | 303 | 116 | 19454 | 5460 |
SEC61B,ENO2,PPP5C,ESR2,FBXO22,UFD1,MYC,SFN,PSMA4,SERPINH1,CKB,HSPA8,ATP5IF1,AKAP1,DDIT3,DNAJC3,DDX39B,PEBP1,HIRA,PXMP2,NAP1L3,UCHL3,STAU1,GPC1,SERPINB6,PRDX3,FKBP1A,PIH1D1,EED,DNM2,OS9,DNAJB9,TTC9C,SUMO2,PDIA3,WWP2,CBL,POU5F1,PEX3,COTL1,AGR2,PCNA,EWSR1,PPWD1,FKBP2,ANP32B,TRIM37,RAF1,ANP32A,B3GNT2,CFAP97D1,EZH2,RPN1,SGTA,TRIM24,CCNF,MRPL53,ENO1,VIRMA,STAT5A,GORASP2,SUGP1,CSK,UBE2H,CALU,CISD1,DNAJC10,PGK1,GPX4,KICS2,SOD1,RPA3,BAP1,IRF3,HSPA5,FBXL19,CFTR,ATG16L1,HEXIM1,RPA2,RPRD1B,PRL,HSP90B1,METTL14,CD274,CAMLG,MDM2,TMPO,PRNP,MIF,SHPRH,HDAC6,ZMYND11,GAPDH,MOV10,DPP4,CALR,PGAM1,ISYNA1,EMC4,EDEM1,EIF5A2,ZC3H11A,DHX9,HSD17B10,HINT1,MEPCE,LSM4,HSPE1,DNAJC30,UBL4A,RRM1,TP53,SOD2,NUPR1,HSPA13 |
| 6.791e-05 | -9.60 | Immunoproteasome | KEGG pathways | hsa_M00337 | 17 | 14 | 7161 | 2463 |
PSMA4,PSMA1,PSMA2,PSME2,PSMB9,PSMA5,PSMB4,PSMB3,PSMB2,PSMB1,PSME1,PSMA3,PSMB10,PSMA6 |
| 6.791e-05 | -9.60 | Immunoproteasome | KEGG pathways | M00337 | 17 | 14 | 7161 | 2463 |
PSMB4,PSMB3,PSMA5,PSMB9,PSME2,PSMA2,PSMA1,PSMA4,PSMB10,PSMA6,PSMA3,PSME1,PSMB2,PSMB1 |
| 6.794e-05 | -9.60 | ZMYND11 (zinc finger MYND-type containing 11) | protein interactions | 10771 | 88 | 42 | 19454 | 5460 |
SRSF1,EZH1,PELP1,FAU,SMAD3,UBE2I,ZHX1,WDR82,TAB1,PRNP,DYNLL1,MAGOHB,TRAF1,VIRMA,RPL10,SRSF10,SMARCA5,ZMYND11,PPIB,TRAF6,SPOP,PPIG,LSM14B,SMAD2,PABPC1,TOP2B,BMPR1A,LTBR,G3BP1,H3C1,MAGEC2,PIAS1,MRPL22,SRSF4,SAP18,MEPCE,TP53,RPL29,TRAF2,EZH2,TFIP11,E2F6 |
| 6.802e-05 | -9.60 | MCFD2 (multiple coagulation factor deficiency 2, ER cargo receptor complex subunit) | protein interactions | 90411 | 80 | 39 | 19454 | 5460 |
NLRP3,PSMD7,PSMD14,SLC35A1,CHCHD4,YWHAG,MCM3,KLHL9,PSMD3,CARS1,UBXN6,SEC13,TXNRD2,LMAN1,COPE,SPPL3,GPX1,PSMD4,TMOD3,PSMD6,SNRPD1,IGBP1,DSTN,SGTA,ACOX1,POLR2D,SYS1,ACTN4,YIPF5,PSMC4,PSEN1,PSMD12,SKP1,HSPA5,CAPZA1,SEPHS1,RIGI,RUVBL2,IDH1 |
| 6.804e-05 | -9.60 | RBM19 (RNA binding motif protein 19) | protein interactions | 9904 | 216 | 87 | 19454 | 5460 |
ARL4D,HP1BP3,PRR3,KRR1,SRP14,SURF6,NOP9,LYAR,RPL7,RPS10,RPS16,NGDN,MOV10,IFI16,RPS2,RSBN1L,NOL12,MPHOSPH10,H2AC4,ZCCHC9,DDX23,RPS24,RPL23A,RPL3,NKRF,FGF3,RPL31,RPL17,RPS13,SRSF4,NOC4L,HMGN4,H1-6,KRAS,RPL15,APOBEC3D,H2AX,H1-3,TOP3B,RAF1,RPL18,LLPH,RPS9,PRKRA,FGFBP1,ZNF330,ZNF22,FAU,RPS3,RPL19,VIRMA,ESR2,SRPK2,RPL35,RPL13A,RPL26,ZNF668,RPL7A,MYC,NSA2,H1-1,UBE2H,RIT1,FBXW11,ZCRB1,FTSJ3,RC3H2,CCDC86,HSPA8,AATF,UTP23,STAU1,NOP53,RPL4,DGCR8,RBMS2,FGF13,RPS14,PABPC5,H1-5,ZNF770,MACROH2A2,UTP15,ZNF574,RPL26L1,RPLP0,APOBEC3C |
| 6.814e-05 | -9.59 | WARS1 (tryptophanyl-tRNA synthetase 1) | protein interactions | 7453 | 175 | 73 | 19454 | 5460 |
CD81,XPO1,NT5C2,PDIA3,PSMG2,AGR2,SMCHD1,TSG101,DNM2,HNRNPL,PRNP,ISG15,PPP2R1A,EEF1A1,SH3GLB1,MTA2,PSMC3,PLS3,EZH2,NME1,ABCE1,ZC3H7A,PCNA,UBE3A,EHD4,CCT8,PSMD12,CAPZA1,RIGI,HNRNPDL,XPNPEP1,HNRNPK,CDK2AP2,KPNA2,ATP5F1A,TUFM,MYC,CTSD,CUL2,CALU,UBE2H,HERC4,CCDC22,FBXW11,GANAB,RTRAF,GNPDA1,OPTN,CTNNA1,USP5,RABIF,NDN,ATP5F1B,CEP41,GMDS,GTF3C4,EHD1,NEK7,NUDT3,ATG16L1,ACSS2,TMOD1,EIF4B,RPA2,PSMA3,BAP1,RPA3,MAPKAPK3,SIRT7,PYGB,HSPA5,GTF2I,STAU1 |
| 6.817e-05 | -9.59 | CLEC4E (C-type lectin domain family 4 member E) | protein interactions | 26253 | 352 | 132 | 19454 | 5460 |
HMOX2,RACGAP1,GORASP2,CALU,ATP1B3,LIG3,UBB,TMOD3,NTPCR,SEC22B,ARHGAP1,TMOD1,ZNF326,RPA2,DLAT,MTDH,SPCS2,ARPC2,RTN4,SYVN1,ITM2B,BANF1,RAB29,RPA3,AIF1L,PDHB,DHRS7,EMC4,KARS1,CALR,TMEM199,TMOD2,OSBPL8,AGPAT1,ESYT1,POR,SEC23A,UBE2G2,CAMLG,PTPN1,SRPRA,LMAN1,DKC1,CXCL9,ARL6IP5,TMEM205,TP53,MRPL11,YTHDF2,CCDC47,PREB,GNAI3,ACTR2,ARPC3,CAPZA2,TFRC,EMC2,SLC25A11,STX8,NSDHL,RIGI,RDH11,PTGES3,FASTKD5,ERLEC1,RAB11A,FMC1,VEZT,SLC7A11,FCER1G,MYO6,ATP1A3,FZD6,SLC30A7,GGT7,VDAC2,GNG12,GNB1,ATP6AP2,ABHD12,TAX1BP1,GPC4,PGRMC1,TOR1AIP2,EFHD1,TOMM22,FAM3C,FAM8A1,HADHA,TAPBP,XRCC5,ATPAF2,DNAJC3,YTHDF1,UFL1,EMC1,FXR2,CBR4,DDRGK1,PDIA3,CLPX,TMEM30A,CDK5RAP3,STX5,SPINT2,XPO5,ADGRG1,PTK7,LANCL1,NUP35,SPTAN1,RAB1B,ERLIN2,TMEM59,ACTN4,EMC10,STBD1,PLD3,TAPT1,PDHA1,STIM1,RPN1,MRPS11,MYO1B,NDUFA4,SSRP1,POLDIP3,RFC3,RAB18,VDAC1,ETFA,EMC8 |
| 6.864e-05 | -9.59 | SMAD-like_dom_sf | interpro domains | IPR017855 | 15 | 12 | 18521 | 5414 |
IRF9,SMAD5,SMAD3,IRF8,IRF7,SMAD4,IRF6,SMAD1,IRF4,SMAD2,SMAD9,IRF3 |
| 6.872e-05 | -9.59 | UTP3 (UTP3 small subunit processome component) | protein interactions | 57050 | 152 | 65 | 19454 | 5460 |
IMP3,E2F4,RPSA,SOX2,CTNNA2,RPL18,RPL31,FGF3,PICK1,RPL3,RPL23A,RPS24,H3C1,KRAS,TF,IMP4,CDCA7L,RPL17,UTP25,IFI16,NGDN,DDX23,CHCHD1,MPHOSPH10,RPS2,TESK1,RPL8,SYNCRIP,SRSF1,KRR1,ZHX1,RPS16,RPS10,FZR1,KCTD10,H1-5,FGF13,RPA2,RPLP0,ZNF574,RPA3,RHOU,EXOSC4,P4HA2,PTN,DGCR8,NOP53,STAU1,MYC,RPL7A,HNRNPC,ZNF668,H2BC9,CEP70,RIT1,H1-1,ZNF330,CSNK2B,PRKRA,RPL37A,FGFBP1,FBXO22,SNRNP40,ESR2,APEX1 |
| 6.872e-05 | -9.59 | LSM12 (LSM12 homolog) | protein interactions | 124801 | 152 | 65 | 19454 | 5460 |
PHB1,FUBP3,CAND1,RPS16,FZR1,OCRL,FAM98A,DCUN1D1,IFI16,MOV10,NDC80,COPS5,API5,EDC3,CTNNB1,SNRNP70,LSM3,DDX1,MED4,LSM14A,PABPC1,ZC3H7A,RTCB,G3BP1,HUWE1,MDC1,SAR1B,RAF1,TOP3B,B3GNT2,E2F4,YTHDF2,SOX2,DSTYK,PDHA1,CCNF,IRF2,PSPC1,SMAP2,RTRAF,RPS20,VIRMA,PRRC2A,ESR2,AAMDC,MYC,CUL3,NTAQ1,BTF3,FAS,EIF3G,BICD2,IGF2BP1,UBE2H,RIT1,CASC3,MCRIP2,RCCD1,HSPA8,NF2,FXR2,YTHDF1,G3BP2,LSM2,NUFIP2 |
| 6.888e-05 | -9.58 | CDH1 (cadherin 1) | protein interactions | 999 | 757 | 260 | 19454 | 5460 |
FAM83B,EFHD2,ESR2,PSMB6,TRIM29,TAGLN2,STAT2,STAT1,SSH3,BAG3,RMI2,SFN,CREBBP,SLC38A1,RPS26,H1-10,S100A11,EP300,HSPA8,XRCC5,DDX39B,LYPLA2,EEF1G,IL6ST,USP6NL,CSNK1A1,EIF4B,KLC2,MAP2K1,PAK2,STX5,SWAP70,ANXA4,HSP90AB1,CTNNB1,TENM3,TOR4A,NGDN,PPFIBP1,RPL6,TAX1BP3,YWHAB,MAGOH,UBFD1,CBL,NCK1,DUS4L,ARHGAP5,MYO1B,CCT8,TMEM87A,CBLL1,RAB8B,PAK6,RUVBL1,ROCK2,KRAS,EEF2,RANBP1,MAX,CRKL,TUBB4B,MACROH2A1,NECTIN2,CCSER2,SRC,ROCK1,CHMP5,CTSB,EIF4H,GORASP2,ARHGAP21,CCNB1,RPL7A,AKT1,SPRED1,SNX5,PTTG1,GLOD4,STXBP6,CCDC65,PRDX6,ARFIP1,HSPA5,TUSC2,ZC3H15,STK38,CFTR,CD2AP,CDC42,SPTBN1,HECTD1,KLF4,IDH2,FGFR1,STX17,SDCBP,CDK6,ADD1,ITGA6,TMPO,SNAP25,PLSCR3,NR2F6,CSNK2A1,USP15,MAP4,RPS2,RPL24,IDH1,GALNT12,ATP2B4,DDR1,PALM2AKAP2,CAPZA1,CSE1L,HNRNPK,H3C1,EGR2,CDK4,SNAP29,SAPCD1,SH3GLB1,NHERF1,BMPR2,NFE2L2,CDH8,EXOC3,CDK8,AP2M1,RAN,FAM91A1,MAD2L2,TUBB,MB21D2,CAPG,HSD17B3,JPT1,PKP4,VEZT,NIBAN2,ILK,HSP90AA1,DCAF4,BRCA1,MYO6,YWHAZ,HADHA,UNC45A,GPC1,NSFL1C,UCHL3,EHD1,ELFN2,DAAM1,NOTCH2,VAPB,CRYAB,KRT8,IGBP1,PLEKHO2,RAB11B,SPTAN1,SNX1,SNX2,PRDX1,PDAP1,LRRC57,AHSA1,VCPIP1,RB1CC1,ARGLU1,NUDT5,HSPD1,ZYX,SCYL2,PLSCR1,FLOT1,ANP32B,AP1M1,LASP1,CCS,ACTN4,RPL29,TPD52,NLRP2,JPT2,CDK5R1,BZW2,TMEM204,CTNNA2,STIM1,CTNNA1,ENO1,CTTN,GAB1,VAMP3,HYCC1,YES1,F11R,LDHA,TMOD3,GMNN,USP14,HYCC2,MAPRE1,EPHA2,STK24,RTN4,ARPC2,MAVS,INPPL1,CDC42EP4,CHMP2B,USP8,YKT6,NF2,FTH1,ARHGAP1,RARS1,MET,SH3GLB2,TMOD1,PICALM,GOLGA5,SLC12A2,LMNA,JUP,CDCA3,TES,EHBP1,SMAD3,PTPN1,HRAS,CAV1,MDM2,IL18,PPP1R18,DAG1,ISYNA1,RELL1,TMEM199,CNN3,ESYT1,SNAP23,LIPA,SEPTIN7,RPL23A,DLG1,RAB1A,EHD4,EIF3E,OLA1,CTNND1,PSEN1,RPL15,LBR,EEF1A1,PPME1,ILF2 |
| 6.893e-05 | -9.58 | vesicle membrane | cellular component | GO:0012506 | 1251 | 424 | 19108 | 5553 |
VPS18,MYD88,TMEM30A,RAB37,SYNGR1,SLC35F1,HPS6,IZUMO1,VPS16,PRRT1,CYB561D2,RAB31,FABP5,BRI3,CLCN6,DNM2,GABRA1,ARF6,OR51E2,PLEKHF2,VAMP7,NCALD,RAB13,SCAMP2,TLR7,LAMTOR2,GJA1,RAB3A,FCER1G,GAD2,BACE1,PML,IRAK4,ATG16L1,CPNE1,PLA2G4B,PCSK9,ATP8A1,RAP1B,KLHL12,STBD1,RAB11A,FOLR1,GABARAPL1,SYNDIG1,ORMDL3,SYNGR3,MDM2,CPE,LGALS3,WASL,TMEM179B,CD59,AP5M1,SYP,MOXD1,CLVS1,VAMP1,SERPINB6,ENPP4,TMEM108,MRC1,YKT6,RAP2C,ACAP2,SNX2,SRI,SNX22,REP15,REEP6,LHFPL2,PARM1,OPRK1,RAB9B,RHOU,STK26,EHD4,LY96,ATP6V1G2,GABRG2,RAB3D,RAB6A,FURIN,CIDEB,SNX17,CD58,RAB32,TASL,SLC6A4,DYNLL1,CACNG3,AP1G2,STX5,ABCC5,UBA52,CPTP,FCGR2A,PDLIM4,DNAJC5,RAB11B,STX10,ADRB2,AP1S2,LDLR,WDR44,PICK1,TLR2,GLIPR1,SEC22B,CD274,DBH,PDIA3,RAB3B,TRAF6,FZD4,NDUFC2,TMEM190,TICAM2,HSD17B6,TRAF2,KDELR1,EHD3,SLC48A1,SNX5,SVOP,EPHA4,ITM2B,AQP2,GABRA2,SNX10,CHMP4C,TFRC,VAMP2,ANXA4,BOK,VTI1B,SLC12A2,RAB18,NCDN,CD36,CAV2,SYNGR2,ICA1,USP8,RAP1A,SYPL1,SELL,TAPBP,SNX14,ABHD6,STX7,RND2,LAMP5,CALY,CD9,LAMTOR3,SCG3,RAB14,BST2,PSEN1,AQP4,RHOBTB1,SNX24,CAMK2G,SEMA4C,VPS26A,LAMP2,ATP6V1C1,UBXN6,NSG1,AGTRAP,SLC31A1,ZNRF1,EXOC3,LRP6,SLC35G2,ANXA7,GOSR2,SLC15A2,ARCN1,EHD1,SGIP1,VAMP5,FGD2,NPC1L1,GRIA1,RAB5A,CD46,CD164,SNX20,HGS,B4GALT1,GRIA2,NCSTN,CYSTM1,COPZ2,CHMP2B,STX17,CD1A,GPR89A,PLD3,ZMPSTE24,ATP6V1G1,SLC39A13,SEC23A,SLC1A1,TICAM1,TOM1,LAMTOR1,SYNPR,SLA2,RAC2,TSG101,TLR3,TBC1D10C,RAB27A,KCNH1,SIGLEC5,SEC13,TMEM45B,TMEM165,MCOLN1,GDE1,NTRK2,CHMP2A,SNAPIN,FCMR,RAB9A,CDIP1,IRF7,RAB35,STX1A,SERPINB10,SPG21,ATG9A,SYN3,SNAP23,PGRMC1,RAB5C,SLC2A8,ATP6AP2,SERPINA5,OPTN,SCAMP5,ARHGAP1,VPS39,APH1A,RALA,SPPL3,GNPNAT1,LAPTM4A,VPS4A,TLR9,SYNGR4,AP2M1,FCGR1A,MMD,LAMP3,HSPA8,STX12,CNIH1,AQP11,SYNRG,VPS28,SYT4,SLC32A1,DIO3,RHOB,PIP4P1,CD1D,SLC30A5,HBEGF,CAMKV,CFTR,CD1B,APPBP2,OCRL,CALR,WNT7A,TBC1D5,TSPAN15,AP1M1,AP2A1,TMED7,RNASEK,NDFIP1,SNX18,STARD3NL,CD3G,MME,RAB4A,UBAP1,SURF4,ATP6V1D,SPRED2,FCAR,SNX1,TMX3,SNX12,DIPK2A,TNFRSF1B,CLIP3,AP2S1,CD47,SLC4A8,CYB5R1,SCYL2,TAB1,TOM1L1,SLC38A9,SNX33,B2M,CHMP1B,ATP6V1A,OLR1,CLVS2,MREG,CXCR1,SAR1B,LDLRAD4,CHMP5,TLR4,AP5S1,SLC17A5,CD1C,HMOX2,PIP4P2,CLIC4,COPE,TMEM95,PRCP,TMEM59,CMTM6,ITGAV,VAMP3,CYB561,TLR1,CD4,WDR83,CX3CR1,CD63,CLCA1,TYROBP,STX16,MYO6,RAB3C,SVIP,GABRB2,RAP2A,RAB22A,FIG4,CHMP1A,SYT2,CLBA1,RAB23,ZDHHC17,DLG4,VAC14,MYO1B,SV2B,SNAP25,RAB1A,PSENEN,AP3S2,KDELR2,FZD6,TLR8,NECAP2,CD14,LMAN1,MARCHF3,BCL2L1,VTA1,SLC11A2,NCK1,CTSD,TMED3,SAYSD1,RNF167,DKK1,LITAF,VAMP8,CAV1,SNAP29,PLEKHF1,RAB8B,AFTPH,LILRA3,STOM,UBE2D3,TBC1D24,TMEM199,RAB39B,SLC2A3,ATP6V0E1,RAP2B,ABHD17A,RPS27A,TF,DEGS1,VPS4B,ATP6V0B,GABRB3,TMBIM1,CORO1C,BORCS5,SNX3,BECN1,TMEM106B,TAB2,RHOG,SLC18B1,STX6,UBB,NECAP1,VPS33A,GPNMB,INPP4A,PDE6D,IL15RA,TLR6,MTMR2,ARHGAP21,CPLX3 |
| 6.949e-05 | -9.57 | MAP4 (microtubule associated protein 4) | protein interactions | 4134 | 288 | 111 | 19454 | 5460 |
ADRM1,VIRMA,SRPK2,CCNF,TUBA1B,PSMC5,RPS20,SNTA1,UBE2H,CCNB1,USP14,LSM8,MARS1,HSPA5,RPA3,BAP1,SIRT7,PML,PRPF4,TWNK,RNF113A,NR1I3,RPA2,CDK1,RARS1,HEXIM1,UBE2M,TRIM36,RPS14,ATG16L1,CAPN1,CDC42,FZR1,PRNP,CDK9,SSBP1,LDLR,LSM3,RPS2,KARS1,HDAC6,TPM3,RAB1A,ABCE1,EMC2,RNF8,STRBP,TP53,TUBB,ACTB,PSMD6,ENO2,SNRPD2,AP2M1,BRCA1,CHTOP,MYC,SFN,CUL2,PSMA4,HNRNPC,PSMD1,BAG3,STAU1,HSPA8,RAB5A,EP300,EMC9,RNF7,PIH1D1,H1-5,PPP1CB,SEC62,EIF2S1,NOP58,HNRNPL,SUMO2,DYNC1I2,DHX15,FOLR1,RXRG,PHB1,PSMD10,HSPB1,PSMD3,GSTM3,WWP2,PFDN5,HNRNPF,LASP1,G3BP1,TRIM37,PSMD12,RPL28,PABPC1,CCT8,BCKDK,RUVBL2,EZH2,NGB,MTA2,POLR2C,MOB3C,TPD52,RAF1,B3GNT2,E2F4,ISG15,PPP2R1A,KIF2A,LGR4 |
| 6.959e-05 | -9.57 | URI1 (URI1 prefoldin like chaperone) | protein interactions | 8725 | 135 | 59 | 19454 | 5460 |
DMAP1,POLR2D,POLR2C,POLR2G,MED9,PPP2R1A,RPAP2,KRAS,NOC4L,RUVBL1,DNAAF10,PDRG1,RIGI,PTGES3,BCL7B,RUVBL2,RPAP3,FAM168A,ASB7,YWHAB,PFDN5,WWP2,XPO1,HNRNPL,NOP58,POLR2I,EGLN3,RPRD1A,POLR2L,PPP2CB,RPRD1B,LMNA,WWP1,PIH1D1,WDR77,POLR1D,PPP1CB,DET1,TRIM52,STAP1,POLR1H,AKAP1,PSMD14,PFDN4,PFDN2,HSP90AA1,PFDN6,POLR1B,RIT1,MAT2A,AKT1,CIAO1,PPP1CC,POLR2B,VIRMA,POLR3B,POLR3H,GTF2F2,POLR2F |
| 6.959e-05 | -9.57 | LRRC15 (leucine rich repeat containing 15) | protein interactions | 131578 | 135 | 59 | 19454 | 5460 |
OAZ3,CACUL1,FSTL1,FBXO3,THNSL1,PLPP6,TFG,FNTB,SRFBP1,TCAF2,TP53,GEMIN7,SGIP1,OTULIN,EZH2,CAPZA2,PNMA2,CACNB3,OR51E2,GATD3,SCG5,RAB39B,SRSF10,MACROD1,RAB11B,CD99L2,FMOD,CPLX3,CBR4,PTDSS1,USP15,TNFSF13,PSMD7,NPSR1,RAB40AL,FOS,FBXL4,FOXP2,KDELR2,SETD3,NEK2,USP6NL,DUSP14,DDIT4L,LACC1,ELMOD1,MMP14,DRD3,DNASE1L1,ESR2,F11R,POPDC2,B3GALNT1,ATG101,ISCA2,CHST9,CSGALNACT1,BLOC1S5,SYP |
| 7.003e-05 | -9.57 | Pfdn2 (prefoldin 2) | protein interactions | 18637 | 28 | 18 | 19454 | 5460 |
PIH1D1,PFDN6,PFDN4,TIMM23,YIPF5,RPAP2,PFDN5,CCT7,PDRG1,PFDN1,RUVBL1,MED17,DNAAF10,COPS7B,RUVBL2,RPAP3,CCT8,CCNF |
| 7.028e-05 | -9.56 | UPF3B (UPF3B regulator of nonsense mediated mRNA decay) | protein interactions | 65109 | 121 | 54 | 19454 | 5460 |
TRIM36,ACACA,HBB,EXOSC4,RLIM,SQSTM1,PYM1,DDX39B,UPF3B,SAP18,UFL1,STAU1,MYC,RAB2A,CIAO1,CASC3,NR2E1,RHOB,RC3H2,RMDN3,SEC61A1,EIF4A3,SRPK2,MAGOHB,WBP11,SOX2,TBK1,RAF1,SLC4A8,EZH2,VPS33A,JAK1,RPS24,RPL31,SLC25A11,MEPCE,KRAS,THRAP3,XPO1,COPS5,CSNK2A1,LAMP3,DDRGK1,IFI16,MAGOH,SNRNP70,SRSF1,ALYREF,PHB1,FZR1,ARF6,CAND1,SNRPA1,NKAP |
| 7.028e-05 | -9.56 | ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1) | protein interactions | 23204 | 121 | 54 | 19454 | 5460 |
TMEM14B,HGS,STARD4,SPG21,YIPF4,FAF2,TP53,RIGI,RETREG1,THRAP3,GAD2,BSCL2,PICK1,GLCE,ESYT1,GAS8,GOLPH3L,RAB5C,TMEM248,RAB33A,SNX2,SNX1,ARL6IP5,ARL4D,MFSD5,FDFT1,SDCBP,LMNA,EHD3,NUDT3,ARL6,FBXW7,FXR2,RNF5,RTN4,RABAC1,RETREG2,SNX11,REEP6,MFSD14B,SCFD1,SNX10,GORASP2,TUFM,NTAQ1,RAB2A,MYG1,SNX3,REEP4,MGST3,UBE2I,SNX12,RETREG3,INPP5K |
| 7.028e-05 | -9.56 | PRMT3 (protein arginine methyltransferase 3) | protein interactions | 10196 | 121 | 54 | 19454 | 5460 |
GFPT1,TP53,SNAP29,SAR1B,CAPZA1,IMMP2L,RNF20,VTA1,HNRNPK,CSE1L,DHX16,PSME1,FAF1,HSPD1,RPS2,HNRNPD,CSTA,ELOC,XPO1,INSYN1,HNRNPA1,GMPPB,EGLN3,CNTROB,OSBP,XXYLT1,SEC23A,PTPN1,EIF4B,RPA2,PSMB7,PRMT2,MCMBP,STAU1,HSCB,ARFIP1,XRCC5,RPA3,DDX39B,PRSS1,NAPA,SAMHD1,PRMT6,MYC,USP5,IDE,PSMD6,ADRM1,STAT1,RPS20,GSK3A,TUBA1B,CTNNA1,CCNF |
| 7.031e-05 | -9.56 | KRT17 (keratin 17) | protein interactions | 3872 | 231 | 92 | 19454 | 5460 |
SHC1,RPS2,EMC4,KARS1,CALR,GAPDH,HDAC6,COPS5,RPS16,FZR1,MBD5,ARL10,RPL12,HRAS,TES,RNF8,TP53,RPSA,FBP1,EEF1A1,HNRNPK,MEPCE,RC3H2,UBE2H,ATP1A1,AGAP2,ATP5F1A,CFL1,EXOC5,PYGM,VIRMA,UBB,ENO1,RPS3,ALB,RPS20,UBASH3B,JUP,CYC1,WTAP,HEXIM1,KRT7,EEF1E1,CFTR,PIK3R2,KDM1A,CRYZ,HSPA5,INPPL1,DLAT,RHOG,HSPB1,CBL,LYZ,RB1CC1,PRDX1,HNRNPA1,HSP90AB1,FUBP3,KRT8,S100A8,RAB6B,PDHA1,EZH2,TUBB4B,RND3,NETO2,EEF2,SNAPIN,RPS4X,HNRNPA2B1,HSPD1,SLC25A5,TRIM21,YWHAZ,CKB,PRSS1,HSP90AA1,CRMP1,HNRNPC,CCDC85B,MCM3,PSMD1,ERH,RNF208,AP2M1,PPT1,EEF1G,CNTN1,ZDHHC17,DDX39B,HSPA8 |
| 7.040e-05 | -9.56 | CYB5B (cytochrome b5 type B) | protein interactions | 80777 | 279 | 108 | 19454 | 5460 |
RPL24,SMAD4,ISYNA1,MOV10,ORC5,NOP9,LMAN1,FNDC9,COG1,ALCAM,CLN8,RAC2,GNPAT,HSD17B11,COQ8A,AIFM1,SRP14,TMEM165,TFRC,GDE1,MTCH2,TBK1,CCDC47,CSE1L,TMX3,EMC2,MFSD14B,ATP1A1,ATP1B3,DNAJC5,CREB3,RAB2A,NDUFAF2,TMEM41A,VIRMA,ENO1,SSR1,GOLGA5,STOM,RPA2,LMNA,CDC42,BNIP3L,TOMM20,MTDH,RTN4,RAB9A,RPA3,HELLS,SLC39A9,STX1A,PDZK1IP1,PEX3,ZCCHC9,RHOG,FAM241A,HNRNPA1,RAB5C,MARCHF5,PLPP4,STOML2,SYNJ2BP,TMEM237,UQCRH,THY1,MFSD5,CORO1C,OTULIN,DCUN1D5,NDUFA12,RPN1,TNPO2,ACTN4,CYB5R1,EMC10,RAF1,TRIM37,KRAS,TMT1A,NDUFA4,FIS1,CGRRF1,CCT2,FAS,SLC30A5,TMEM38B,TNPO3,REEP4,SEC61B,RETREG3,CYB5R3,CAV2,PLAA,DUSP22,DET1,OTULINL,SEC62,TOR1AIP2,COIL,PHB2,EMC1,HSCB,NPTN,SDHAF4,AKAP1,HSPA8,HSDL1,DUSP9 |
| 7.060e-05 | -9.56 | REL (REL proto-oncogene, NF-kB subunit) | protein interactions | 5966 | 380 | 141 | 19454 | 5460 |
TRAPPC6A,NMRK1,SLC6A12,TIMM13,GPC4,NDUFAF3,CDKN1A,NDE1,EHHADH,SKP1,TSR3,GPC1,ADRB2,HSPA8,SAT1,EP300,HADHA,ATPAF2,RPS26,FHIT,SP1,POLR1B,HTRA2,ARMC7,FBXW11,SLC41A3,PRPF31,ZDHHC24,LMO2,OST4,CREBBP,PAPOLA,CDKN2D,PSMA4,GADD45G,MAD2L2,RABIF,CLIC4,MB21D2,FOXP3,CPSF1,NFKBIA,SCNM1,NFKBIB,STK16,NGB,PSORS1C2,SPG21,ELF1,CKS1B,HNRNPF,LASP1,CHCHD2,ZBTB16,PSMA1,TMEM268,PICK1,OAZ3,BAG2,DNTT,AKT2,CDKN2C,STAMBPL1,SLC39A13,IKBKB,SHC3,XPO1,EIF3D,ATG9A,RPL6,EGLN3,CIB3,CGGBP1,CEP19,NABP1,POLR2L,SDCBP,TCP11L1,TRIM68,LSM2,MRPL10,CHIC2,MBD3,BCL6,UBE2K,GTF2I,MIEN1,SQSTM1,GID8,RAB29,EXOSC1,FKBP1B,MTPN,CTNNBIP1,AR,C9orf72,DHPS,MORF4L1,VIRMA,MAGOHB,TRIM27,UBASH3B,CCNF,CINP,EIF4A3,PPP4C,SPRY1,MSRB3,TMEM165,NECAP1,NFE2L2,SOCS3,EXOSC8,POP5,TBK1,TP53,TSSC4,PAK1IP1,KPNA2,SEPTIN7,CPNE2,EFHC1,NKRF,SMG9,ZNF688,EIF5A2,TRAPPC2L,NXT2,CSNK2A1,GRAP,NFKB1,FNDC11,KLHL32,ACOT8,EPHB6,THOC1,TSC22D3,GTF2B,CDR2L,CXCL14,EIF4E2 |
| 7.066e-05 | -9.56 | LGALS3BP (galectin 3 binding protein) | protein interactions | 3959 | 276 | 107 | 19454 | 5460 |
DNAJC25,CRTC2,FAF2,SOX2,TUBA1A,RAF1,EZH2,TUBB4B,BAG2,HSPD1,BCKDK,CCT8,UBE2A,RPS4X,PAX6,CPEB1,SIGLEC5,WWP2,VCPIP1,RPL23,TRAF6,DROSHA,ARHGAP25,MAGED2,TRAPPC10,PHB1,HSP90AB1,CCT7,TCP1,PPT1,HSPA8,GPHN,HDAC5,NT5C3A,ITGAV,FXR2,PHB2,SAMHD1,MYC,CUL3,CUL2,NTRK3,HSP90AA1,SP1,CCT2,BRCA1,PHKB,IRF2,TUBB,DYNLL1,ACTB,LGALS3,H2AX,CD248,TBK1,KBTBD4,CD14,CCT5,PPME1,SELENOF,CD209,SURF4,IGF1R,NKRF,CTNND1,RIGI,NEDD8,COPS5,MZT2B,TUBG1,PPIC,CD9,SHC1,EFNA3,SYNCRIP,ITGA6,ETV6,DNAJC1,CAND1,MIOS,DCUN1D1,PRNP,GABRA1,MX1,CFTR,MET,ACACA,TWNK,SQSTM1,RPA3,DVL2,PRPF4,HSPA5,SLC25A51,ARHGAP21,FBXO7,DNAJC5,VAMP5,FOXA3,DNAJC19,UBE2H,LGALS8,GANAB,TRIM27,UBASH3B,CCNF,VIRMA |
| 7.075e-05 | -9.56 | transport vesicle | cellular component | GO:0030133 | 437 | 164 | 19108 | 5553 |
RAB11B,ERG28,NCSTN,MTMR2,STX10,CPLX3,RAB5A,DNAJC5,ERP29,AP1G2,STX5,SLC4A8,GRIA1,STX6,MT3,SLC18B1,CIDEB,PDE4B,SPRED2,RAB3D,ATP6V1D,FURIN,RAB6A,BLOC1S5,ARCN1,SURF4,PCSK2,BORCS5,STX11,GOSR2,MME,ATP6V1G2,TMED7,AP1M1,AP2A1,SLC35G2,NRSN2,YIPF3,OPRK1,ZNRF1,ATP6V1C1,RAB8B,YKT6,AFTPH,SEMA4C,CHGA,RABAC1,SLC30A5,VAMP1,IGF1,RAB14,SYP,OVGP1,PSEN1,CD59,SCG3,TMED3,SLC32A1,CPE,TMEM168,PICALM,STX7,SYNRG,SYNDIG1,FOLR1,TMED9,SYT4,LAMP5,SYNGR3,BET1,RAB11A,BCL2L1,COPS4,CTTNBP2,ATP8A1,KDELR2,PPFIA2,CNIH1,HSPA8,STX12,LMAN1,KLHL12,NPTX1,PSEN2,SYPL1,SYNGR4,BACE1,SV2B,LGI3,GAD2,RAB1A,TRAPPC4,ICA1,SNAP25,GOLGA5,SCAMP5,CAV2,RAB3A,SYNGR2,APH1A,DLG4,CLBA1,ATP6AP2,SYT2,BLOC1S3,SYN3,VTI1B,CLRN1,RAB5C,RAB9A,ROGDI,SNAP91,SPG21,VAMP2,SEPTIN6,STX1A,NRSN1,IQSEC1,CHP1,AQP2,RAB13,COPS5,SNAPIN,RAB3C,GABRA2,SEC13,VAMP7,NTF4,AZIN2,NCALD,STX16,SVOP,PLEKHF2,KDELR1,GABBR1,RAB27A,VAMP3,COPE,RAB40AL,HCRT,PRRT1,SYNPR,SLC17A5,SEC23A,SYNGR1,SAR1B,ATP6V1G1,RAB3B,DISC1,SLC35F1,AP1AR,SSPN,STX17,TMEM30A,ATP6V1A,SEC22B,GOSR1,DBH,PPT1,AP1S2,B2M,RAB1B,COPZ2,PICK1 |
| 7.075e-05 | -9.56 | cell-substrate junction | cellular component | GO:0030055 | 437 | 164 | 19108 | 5553 |
ARF1,RALA,CAV2,DAG1,LIMS2,RPL31,G3BP1,FLRT3,YWHAB,NCKAP1,ITGA2,RND3,HSPA8,FERMT2,TM4SF20,RPL27,HNRNPK,RPL9,YWHAG,CHP1,RPL19,ITGB5,ILK,PPFIBP1,RPLP1,ZYX,GJA1,SNAP23,RPS11,CTNNB1,GIT2,RPS29,IRF2,CNN3,JAK1,SDC4,FLOT1,RPS7,TES,ARPC3,SHC1,RPL8,ITGAV,RPL6,DNM2,RPS10,AIF1L,EHD3,EPHA2,ITGA6,ITGB8,LPXN,RPL22,ARPC2,RPS16,ARF6,RPL12,STX16,LCP1,ACTB,ACTR2,RPL3,CDH13,ICAM1,GDI2,B2M,LASP1,SRC,MAPRE1,JAK2,L1CAM,RPS5,PIK3R2,RPL13A,PDIA3,RPS17,CD81,HMGA1,RPL7,CSRP1,RPLP2,FAM107A,RAC2,RPL37A,SLC6A4,PPIA,LAP3,RPS4X,CD99L2,DPP4,CFL1,TGFB1I1,HSPA5,CD46,NCSTN,AKAP12,PTK7,DCTN4,ATAT1,YWHAZ,NME2,RPS9,PIP5K1A,MME,SDCBP,CD151,RHOU,FHL3,ARL14EP,CORO1C,PPIB,CIB2,PPP1R12A,MAPRE2,RHOG,TADA1,ACTN4,YES1,RPLP0,CAV1,RPL18,RPS2,MAP2K1,MDC1,NECTIN2,HSP90B1,RPL7A,RPL10A,REXO2,CTTN,RPS14,PABPC1,CALR,CDC42,RPL4,KRAS,RPS3,RPL23,HACD3,RPS15,CD9,HSPB1,ADD1,CTNNA1,ALCAM,PPP1CB,CAPN2,LAMTOR3,NRP1,JUP,MSN,CAPN1,MMP14,CAV3,RPS13,RHOB,CBL,CD59,CASK,TRIM15,PPP1CC,RRAS2,THY1,FLRT2 |
| 7.099e-05 | -9.55 | LARS2 (leucyl-tRNA synthetase 2, mitochondrial) | protein interactions | 23395 | 155 | 66 | 19454 | 5460 |
HSPD1,COX8A,HINT2,HSD17B8,RASL10B,ATP5F1D,KRAS,ABHD10,IMMP2L,FASTKD5,MRPS17,MRPL11,UBL5,TOP3B,PDHA1,GFM2,COX4I1,SSBP1,SDHB,FAHD1,GATD3,YBEY,RMND1,WIF1,MALSU1,PFDN5,GRSF1,MTRF1,CBR4,SMAD4,RHOG,TST,MRPS26,AMACR,EXD2,RPA3,RHOU,GFM1,HSCB,NPTN,CRYZ,MRPS7,DUSP22,HCST,TIMM13,GRM2,ACAA2,RPA2,MTRES1,TFB1M,CCDC90B,LIG3,OPTN,TACO1,GPX1,VIRMA,MRM2,PMPCA,ETFBKMT,AUH,MTG2,TUFM,PCCB,FBXW11,TAFAZZIN,RIT1 |
| 7.099e-05 | -9.55 | TNKS1BP1 (tankyrase 1 binding protein 1) | protein interactions | 85456 | 155 | 66 | 19454 | 5460 |
HSCB,KDM1A,FBXW7,DCTN3,SQSTM1,RPA3,PML,SIRT7,RPA2,CFTR,SPTBN1,DYRK1A,FANCD2OS,ACTB,GSK3A,TRIM24,PHF21A,CCNF,CNOT6,UHMK1,RC3H2,GADD45B,BTF3,PSMD1,USP14,RAB2A,CEP85,RAB11A,CNOT6L,TNKS2,CCAR1,FLOT1,CAPZA1,RIGI,KRAS,G3BP1,CNOT7,TOLLIP,HNRNPK,ZYX,S100B,GARRE1,GPBP1L1,NUPR1,MOB3C,EZH2,CBX3,CAPZA2,TOP3B,B3GNT2,YTHDF2,EGLN3,CAV1,CDC5L,ARF6,TSG101,TNKS,TES,RAB35,PSMD7,YWHAH,XPO1,CSNK2A1,IFI16,NFKB1,CNOT2 |
| 7.103e-05 | -9.55 | A2M (alpha-2-macroglobulin) | protein interactions | 2 | 181 | 75 | 19454 | 5460 |
SCGB1D1,AGPAT1,RAB3A,MED4,STAMBPL1,LYZ,TNFRSF14,RAP1B,IL10,GJA1,KCTD15,KLK3,TRIM6,RAF1,UBR7,H2AX,SOX2,ADAMTS1,CYP2C8,PHC1,PDE6D,CCR1,GALNT12,IGF1R,EGFL8,CDK2AP2,FARSA,KRAS,SMN1,PAEP,PDE2A,SLC6A4,HMOX2,UFD1,RHEB,ALKBH5,UBE2H,OAT,FIS1,ATP1A1,PDF,EXOSC1,HSP90AA1,TUBA1B,ENO2,EGLN2,ACTB,UMPS,NDN,PRDX2,CTSB,TOM1L1,DUSP14,RETN,CDK7,CDKN1A,CFTR,CDC42,IL4,FKBP14,STX17,VAV2,ANXA7,LEP,FBXW4,NCDN,CYP2C18,EGFL7,HSPA8,HSPB2,IL1B,TTR,B2M,HSPA5,RPP14 |
| 7.103e-05 | -9.55 | GRIPAP1 (GRIP1 associated protein 1) | protein interactions | 56850 | 181 | 75 | 19454 | 5460 |
KRT8,TES,PSMB1,CEP57L1,EEF1AKMT3,RPRD1A,RAB35,NUF2,HMG20A,CCT7,PRPF18,STX6,PPP1R18,GAS8,EXOC1,USP2,LAMP2,HSPB1,TSNAX,RPS2,SMAD4,SPP1,RHOG,TCEA2,TFPT,ENKD1,RIGI,ZNF365,TRAF2,MLLT6,SNAPC5,MAX,RAD1,RAB4A,DISC1,TFRC,ZMAT2,PHF21A,GRIA1,S100A6,SMURF1,ADRM1,ACTB,TTC23,SMARCE1,RAB11A,ZNF250,SMAD2,CCHCR1,BICD2,LAMTOR1,RAB5A,RAB9A,FAM50B,CYB5D2,RPA3,STAP1,STX7,OIP5,DUSP26,KDM1A,PPP1CB,CCNH,EHHADH,FAM161A,ING5,ATG16L1,MYL6,MFAP1,ARL15,GIT2,FEM1A,GOLGA5,FGFR1,RPA2 |
| 7.116e-05 | -9.55 | TIR | prosite domains | PS50104 | 26 | 17 | 12186 | 3388 |
TLR7,TLR3,TICAM2,SARM1,TICAM1,TLR8,TLR2,PIK3AP1,TLR5,TLR4,TIRAP,IL1RAP,TLR1,TLR10,TLR6,MYD88,TLR9 |
| 7.121e-05 | -9.55 | UBA1 (ubiquitin like modifier activating enzyme 1) | protein interactions | 7317 | 340 | 128 | 19454 | 5460 |
TSSC4,HUWE1,KPNA2,SOS2,HSD17B10,RAD23B,TFCP2,UBE2B,EEF1A1,KBTBD4,GBE1,TP53,TMCC2,UBTD2,G6PD,PRNP,RAC2,UBE2N,UBE2G2,EEF1AKMT3,TAF9,HDAC6,COPS5,MZT2B,KARS1,EMC4,GRPEL1,MARS1,UBE2K,SQSTM1,RPA3,SOD1,SEPTIN6,BAP1,HELLS,IRF3,HEXIM1,UBE2M,ACACA,RPA2,CDK1,GABRA1,CFTR,ATG16L1,UBE2W,EEF1E1,ARHGAP1,UBE2L3,VIRMA,DNPH1,SMAD5,NDN,KCTD9,BUB3,ARMC6,PTEN,CCNF,CDC73,UBE2H,UBE2E3,PPTC7,MTPN,USP14,IFNAR1,GORASP2,MAT2A,CAP2,UBE2A,AP1M1,RPS27A,RAD21,G3BP1,KRAS,XPNPEP1,PABPC1,HNRNPA2B1,ABCF1,HGS,EZH2,NGB,SOX2,GFPT1,HSP90AB1,HNRNPL,SUMO2,ARHGAP25,AHSA1,MGMT,UBE2D1,FKBP4,YWHAH,YWHAG,XPO1,IFI16,MARCHF5,UBE2E2,FRA10AC1,UBE2D3,UCHL3,STAU1,HSPA8,BIRC2,HDAC5,CRY1,DNAJC3,PIH1D1,NEK7,EDEM3,FBXO42,PGRMC1,USP5,ESR2,TAX1BP1,DLST,UBE2S,HSP90AA1,PFDN4,SP1,RIT1,RHOB,BRCA1,YWHAZ,PSMD14,FBXW11,BAG3,MYC,CUL3,LDHB |
| 7.123e-05 | -9.55 | DNM2 (dynamin 2) | protein interactions | 1785 | 267 | 104 | 19454 | 5460 |
PHB1,FBXO32,DNM2,CCT7,EGLN3,SNX18,DDRGK1,PPIB,PIK3R1,MPHOSPH6,HNRNPD,NCK1,AGR2,RTCB,RUVBL2,EFNB1,RBM3,KRAS,ZBTB16,GTF2E2,SNAPIN,CRKL,SMARCB1,POLR2C,CCR1,VPS33A,ANAPC2,CCDC90B,SCN2B,ESR2,DYNLL1,SLC30A5,BAG3,RIT1,DNAJB6,H1-10,EP300,HSPA8,DDX39B,PACSIN3,STAU1,FXR2,RPE,EHD1,ZER1,NUFIP2,PALS2,SEC23A,TES,CD274,HRAS,CDC5L,CDK9,GMPPB,RPS2,SHC1,H2AC4,CCR5,CAPZA1,MRPS18C,MEPCE,DYNC1I1,RPAP2,TP53,MTCH2,GBE1,RNF8,GRAP2,SH3GLB1,AMIGO1,CTTN,OPTN,VIRMA,SRC,SH3BP4,LYPD6,PYGM,BUB3,NTAQ1,PTPN11,UBE2H,AP2A1,TYROBP,ZFAND6,SNX33,MAVS,HMCES,SIRT7,PML,RPA3,BAP1,RHOU,HMGB1,FBXW7,CFTR,CD2AP,MND1,HCST,ATG16L1,PICALM,FGFR1,RPA2,CDK1,SDCBP |
| 7.136e-05 | -9.55 | SLC25A46 (solute carrier family 25 member 46) | protein interactions | 91137 | 264 | 103 | 19454 | 5460 |
BSCL2,EMC2,NUP107,FKBP8,CCDC47,PREB,SNAP29,MTCH2,LBR,APOO,MTARC2,NEFL,SRPRA,PTPN1,CAMLG,EHBP1,ARMC1,HSD17B11,SEC23A,TRAK2,TMPO,FUNDC2,LMAN1,EMC4,HM13,MFN1,TMEM11,MUL1,ESYT1,TEX264,SLC22A6,MAVS,MTDH,YKT6,BNIP3L,TMEM209,SLC5A6,RABL3,ARHGAP1,SEC22B,SLC22A8,SAMM50,PDCL,LEMD3,OPTN,CCNF,CHCHD6,IL2RA,SLC7A8,SEC63,C9orf72,SEC13,CISD1,MFSD14B,FHL3,USP30,S100A10,VDAC1,LEPROTL1,STBD1,FAF2,ERLIN2,RPN1,STIM1,AQP3,CRELD1,SLC66A2,STX5,NUP35,DDX50,STOML2,MARCHF5,DDRGK1,PDCD1,HAX1,EXD2,TACR1,TXNL1,AKAP1,EMC1,SLC15A1,FBXL4,TOMM22,TOR1AIP2,MTX2,FUNDC1,VAPB,UBAC2,ARMCX3,RMDN3,SPCS1,REEP4,APLNR,CHCHD3,VEZT,GPR17,OPRM1,TOMM40,LAMTOR1,LMNB1,BAX,FIS1,SCFD1 |
| 7.140e-05 | -9.55 | PRR3 (proline rich 3) | protein interactions | 80742 | 246 | 97 | 19454 | 5460 |
MALSU1,DKC1,NOP9,MRPL24,KLF1,RPS16,MRPL50,PRR3,SYNCRIP,MRPS9,KRR1,MGME1,RPS2,CLP1,APOBEC3F,CMSS1,MOV10,MRPL22,RPS13,SRSF12,MRPS18C,RPL17,NOC4L,HNRNPK,MRPS18B,MRPL52,NKRF,MRPL51,EXOSC8,STRBP,MRPL47,MRPS21,PRKRA,MRPS28,RPS3,ELAVL2,CDKN2AIP,MRPS16,RPL26,ZSCAN25,MRPL20,ABCC2,UTP23,RPS15,MRPL17,ZNF574,RPL26L1,ZNF770,MRPS34,ZNF326,RBMS2,FGF13,LRWD1,HNRNPL,RPS10,HP1BP3,MRPS26,MRPL9,MRPS35,ASF1A,MRPS11,SRSF8,RPL31,RBM3,PABPC1,CRKL,PAIP2B,E2F4,RPL19,MATR3,LAMTOR3,RPS9,MRPL13,ZNF22,RPS5,MCAT,TSEN54,FYTTD1,ZCRB1,MRPS25,ZNF668,MRPL16,APOBEC3B,MYC,HNRNPC,MRPS7,HNRNPA0,NOP53,MRPL57,CCDC86,PSMA3,RAMAC,NGRN,SNRPA,MRPS18A,APOBEC3C,PABPC5 |
| 7.149e-05 | -9.55 | SEPTIN9 (septin 9) | protein interactions | 10801 | 249 | 98 | 19454 | 5460 |
LSM14A,PABPC1,HSPD1,MYO1B,KRAS,FLOT1,E2F4,RAF1,ACTN4,PDHA1,EZH2,VAMP2,PLS3,NIM1K,MOB3C,ATP6V1A,EED,HNRNPL,UBXN6,PDIA3,ACTR3B,NDUFV2,XPO1,AGR2,HNRNPD,STAU1,CD59,MRPL12,PPP1CB,VAPB,PIH1D1,PELO,TRMT6,GNG12,FBXO22,TENT5C,PSMD6,ATP5F1B,ESR2,CUL3,HNRNPC,MYC,BTF3,JPT1,RBM27,BRCA1,MYO6,SERPINH1,LSM14B,ICAM1,EXOC8,PPP1R12A,SNAP23,SEPTIN7,CPNE2,TP53,NUPR1,GNAI3,CD274,HRAS,MCL1,PRNP,PPP1R18,TMED9,CAV1,CDC5L,CDK9,GOLPH3L,TPM3,COPS5,KPNA1,PML,RPA3,SEPTIN6,BAP1,MTDH,LRRC3,CDC42EP4,HSPA5,SEC22B,PSMC4,CFTR,CD2AP,CDC42,FGFR1,RPA2,TRIM36,PRKCA,CCNF,MSN,VIRMA,DYRK1A,SUCLG2,FERMT2,GORASP2,BICD2,MAPRE1,STK11 |
| 7.187e-05 | -9.54 | LUZP4 (leucine zipper protein 4) | protein interactions | 51213 | 99 | 46 | 19454 | 5460 |
RPS13,POLDIP3,THRAP3,SRSF7,PALM2AKAP2,PPP1R12A,PLS3,H1-3,ACTN4,RPS7,RPSA,SRSF10,PPP1R18,THOC1,THOC2,ALYREF,SRSF1,DDX1,TMOD2,MAGOH,FOSL2,RPL24,CSNK2A1,SAP18,AIF1L,RPS15,APPBP2,DDX5,DDX39B,FOS,BANF1,SPECC1L,H2AC7,PPP1CB,EFHD1,RPL27A,SRPK2,ERH,RPL22,RPL35,MACROH2A1,EIF4A3,CHTOP,CFL2,RPL26,STK38L |
| 7.187e-05 | -9.54 | KCTD12 (potassium channel tetramerization domain containing 12) | protein interactions | 115207 | 99 | 46 | 19454 | 5460 |
HECTD1,TPD52L1,RARS1,NUFIP2,LMNA,RPA2,CDK1,KCTD12,TOMM22,ARHGEF39,YTHDF1,TSR3,PDHB,RCCD1,RPA3,LCA5,BAP1,DVL2,TIA1,CUL3,AKT3,CEP97,GABPA,RPGRIP1L,LGALS3,RANBP6,RAB14,GTF2F1,CCNF,NUDT16,KCTD16,TOP3B,RPS4X,SOCS2,KRAS,EWSR1,RPL23,KPNA1,RPL24,DDRGK1,GNG2,CLPX,GSTM3,CEP19,OSBP,CD274 |
| 7.187e-05 | -9.54 | BNIP3 (BCL2 interacting protein 3) | protein interactions | 664 | 99 | 46 | 19454 | 5460 |
CLEC7A,MAP1LC3B,TMEM205,MTCH2,TMEM101,MAP1LC3A,CLN8,SEC23A,RAC2,RPRM,TLCD4,FATE1,ZDHHC15,TMEM30A,BCL2L1,FAM241B,TMEM11,TM4SF18,AKAP1,SQSTM1,TMX2,JAGN1,ATP5MK,FBXL4,BNIP3L,PLP2,SEC22A,ENPEP,MTX2,LMNA,CLDN9,AMIGO1,ELOVL4,GPR37,RNASEK,ESR2,CD47,RHEB,BAG3,CREB3,SCN3B,MFSD14B,BAX,HTRA2,TMEM106C,PPTC7 |
| 7.187e-05 | -9.54 | ZBTB11 (zinc finger and BTB domain containing 11) | protein interactions | 27107 | 99 | 46 | 19454 | 5460 |
RPS2,E4F1,MOV10,ZCCHC10,RPL6,FZR1,RPS10,RPS16,CGAS,RPL7,RPL8,KRR1,SRSF1,H2AX,RPSA,SRSF4,RPL17,RPL3,RPL31,PPAN,H1-1,ZCRB1,RPL26,ZNF668,MYC,ATP6AP2,DYRK1A,RPL10,RPL19,ESR2,SNRNP40,RPL35,RPL13A,RPF1,PRKRA,PHF21A,RPS9,RPS3,ZNF330,ZNF574,RPLP0,APOBEC3C,COIL,RPL4,RNF113A,SIRT7 |
| 7.212e-05 | -9.54 | ovary-low_malignant_potential_(borderline)_tumour-serous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-serous | 32 | 20 | 16828 | 4835 |
SMAD4,HRAS,KRAS,PIK3R1,IDH1,FGFR1,PIK3CA,PTEN,DICER1,RB1,MET,KIT,CTNNB1,BRCA1,TP53,JAK2,AKT1,IDH2,FBXW7,PPP2R1A |
| 7.238e-05 | -9.53 | PPFIBP2 (PPFIA binding protein 2) | protein interactions | 8495 | 42 | 24 | 19454 | 5460 |
CLK1,TRIP4,SPECC1L,RIGI,KRAS,SOX2,SNAP29,CCR1,CRKL,PPFIA2,TSG101,PPFIA3,HRAS,RTL6,HNRNPL,PRNP,H2BC9,YWHAH,PPFIBP1,YWHAG,API5,SFN,PSMD14,YWHAZ |
| 7.238e-05 | -9.53 | ADORA2B (adenosine A2b receptor) | protein interactions | 136 | 42 | 24 | 19454 | 5460 |
DDX39A,TMBIM6,SYNGR2,GGCX,FAM241B,SURF4,GOLGA5,GTF2IRD1,SIGMAR1,ZNF267,RETREG3,SLC30A7,LPAR2,XPO5,SLC39A10,TMEM87A,SDC4,SCAMP2,TSPAN15,LRP10,VKORC1L1,NOP9,PGAP4,REEP4 |
| 7.245e-05 | -9.53 | Spliceosome, U4/U6.U5 tri-snRNP | KEGG pathways | M00354 | 30 | 21 | 7161 | 2463 |
TXNL4A,LSM3,LSM6,SNRPG,SNRNP40,PPIH,LSM5,SNRPD3,SNRPB,LSM8,PRPF4,SNRNP27,SNRPD2,SNRPD1,SNRPE,LSM4,CD2BP2,USP39,LSM2,PRPF31,DDX23 |
| 7.245e-05 | -9.53 | Spliceosome, U4/U6.U5 tri-snRNP | KEGG pathways | hsa_M00354 | 30 | 21 | 7161 | 2463 |
PRPF31,DDX23,USP39,LSM2,SNRNP27,PRPF4,SNRPD1,SNRPD2,SNRPE,LSM4,CD2BP2,LSM8,SNRPB,SNRPG,SNRNP40,PPIH,LSM5,SNRPD3,TXNL4A,LSM3,LSM6 |
| 7.249e-05 | -9.53 | IRAK4 deficiency (TLR2/4) | REACTOME pathways | R-HSA-5603041 | 11 | 10 | 10285 | 3229 |
MYD88,TLR6,TIRAP,CD14,TLR4,TLR1,LY96,IRAK4,TLR2,CD36 |
| 7.249e-05 | -9.53 | MyD88 deficiency (TLR2/4) | REACTOME pathways | R-HSA-5602498 | 11 | 10 | 10285 | 3229 |
IRAK4,TLR2,CD36,LY96,TIRAP,CD14,TLR1,TLR4,MYD88,TLR6 |
| 7.269e-05 | -9.53 | PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1) | protein interactions | 9088 | 138 | 60 | 19454 | 5460 |
TMT1A,RNASEH2C,MAPK10,DNAJC25,TMEM101,CKS1B,TOP3B,CTXN1,RPN1,STIM1,SPINT2,HP1BP3,HSD17B11,MFSD5,EEF1AKMT3,ACTA2,THOC2,PTPN1,TMPO,DNAJC1,FATE1,MARCHF5,RAB5C,H2AC14,DRG1,RHOG,DERL1,HADHA,CLDN8,OR1M1,SNX11,TMX2,CHRNA7,STX7,PXMP2,SMC4,ST7,CCNA2,SEC62,TMEM106A,OTULINL,EFHD1,CKS2,SSR1,CDK1,LMNA,TMEM229B,PTEN,SEC61B,RETREG3,ELOVL4,SEC63,EIF4H,CCNB1,ZMPSTE24,ATP1A1,MFSD14B,NOA1,H2AZ2,LMNB1 |
| 7.304e-05 | -9.52 | positive regulation of transferase activity | biological process | GO:0051347 | 381 | 147 | 18204 | 5365 |
WRAP53,TPD52L1,ANGPT1,PTPN1,SRC,GHR,PSRC1,MIR26B,PTGES3,FGFR1,TLR4,LEP,DLG4,CD200,HNRNPA2B1,PIK3CG,MAP3K12,HSP90AA1,KLF4,PRNP,PHB2,TCIM,TAB2,IL12B,IFNG,TLR3,EPHA4,CCL5,DIPK2A,CCNY,MAGEC2,DUSP19,FZR1,PPIA,NEK7,CD86,SERINC1,CDC20,IGF1R,TOM1L1,CACUL1,ERP29,MYC,FERMT2,IL4,RGCC,PRKCQ,CDKN1B,EMP2,CAMK1,NBN,RPS2,MIR21,CD4,UBE2S,NTRK2,LCP2,NTRK3,TCP1,UBE2I,DSTYK,RBCK1,TNKS,IL34,TAB1,PRKAG1,CHRNA7,EZH2,PRIM2,HSP90AB1,AGAP2,IL23A,IL1B,CD40,AKT1,RALB,EPHA2,TNFSF15,RFC2,GREM1,ADRB2,STK11,PROX1,HRAS,CAB39,CCR7,TLR6,FBXW7,TGFB2,MAP2K3,TNF,ADIPOQ,PDCD10,PARM1,RFC3,IGF1,MAP3K11,DKC1,CCND3,PHB1,RPS3,MT3,TXN,PCNA,RAP1A,TRAF2,GH1,HNRNPD,UBE2L3,RFC5,KIT,TRAF6,DDR1,MET,LMO4,NEK2,DLG3,CARTPT,DIRAS2,XRCC5,CCL19,SKP1,DIRAS1,F2,TGFBR2,TOPORS,ARRDC3,CCND1,CDKN1A,ZNF622,MAPKAPK5,FGF1,PKIB,RFC4,JAK2,PTEN,CHI3L1,MMD,CCT2,PSMD10,STRADB,BAD,FCGR1A,MAP2K1,GSK3A,PIH1D1,DVL2 |
| 7.332e-05 | -9.52 | LSM_dom_sf | interpro domains | IPR010920 | 23 | 16 | 18521 | 5414 |
LSM6,LSM10,SNRPD3,LSM5,LSM14B,SNRPG,SNRPD2,LSM14A,LSM4,SNRPD1,LSM3,SNRPN,LSM8,LSM2,SNRPB,SNRPE |
| 7.427e-05 | -9.51 | PSME2 (proteasome activator subunit 2) | protein interactions | 5721 | 124 | 55 | 19454 | 5460 |
WWP2,PSMD3,MGMT,CBL,PSMD7,PSMD10,PSMG2,PSMB1,PSMB5,PSMB4,PSME2,FZR1,PSMB9,MTCH2,UBL5,PSMC3,PLD3,HSD17B10,PSME1,RPL31,RNF26,PSMB10,PSMD12,PSMA5,PSMA1,PSMA2,SEM1,BAG3,PSMD1,FBXO7,PSMA4,PSMB2,EPHA2,PSMD14,PSMC5,PSMA6,CCNF,VIRMA,PSMB6,SH3BGRL,PSMD6,TENT5C,PSMD4,CFTR,PSMB3,PSMC4,PIH1D1,STX17,PSMB7,SDCBP,PSMA3,HSPA8,SIRT7,SOD1,PSMC1 |
| 7.427e-05 | -9.51 | neuronal cell body | cellular component | GO:0043025 | 489 | 181 | 19108 | 5553 |
HSP90AB1,CPLX1,PCSK2,FUBP3,SLC4A10,GLRX2,AMIGO1,SRSF10,MME,SMN1,PDE1A,C9orf72,CD40,SCN1B,RCVRN,SLC8A1,BRINP2,SLC4A8,TNFRSF1B,THY1,PHAX,KCNC1,CDK5R1,ALCAM,SLC6A6,PMM2,SYT4,HTR5A,SLC25A27,FBXW11,ELAVL4,ASIC2,OPRK1,PPP2R1A,YKT6,BRINP3,FZD3,TMEM50A,PGRMC1,FBXO31,NRSN1,UPF3B,KCNJ11,TAC1,PDE9A,SLC6A2,HSPA8,ADAM21,GAD2,BACE1,SLC6A3,NQO1,SLC38A1,CDK5,CD200,SLC1A1,PDE1B,KCNJ2,STAU1,ASTN1,ZC4H2,CX3CL1,HOMER1,SLC38A7,L1CAM,SRC,FEZ1,CRYAB,PAFAH1B1,RRM1,TMEM266,ELK1,KCNH1,BGLAP,MUL1,MOB4,MAP1B,IL6ST,GLRX5,IGF2BP1,MAGOHB,SLC1A3,SLC6A1,LPAR1,KLHL1,BMPR1A,PDYN,LRP6,PTK7,AKAP12,BMPR2,GRIA2,GHR,RAB5A,FKBP4,CCN3,SOD1,UCN,MIR107,GRIA1,S100B,IGF1R,UBB,GSK3A,SLC38A2,PSEN1,EFHC1,LYPD6,CAPN2,PICALM,CCR4,TIAM1,ATP1A2,KCND2,SLC2A3,NRSN2,CDC42,NEGR1,ENC1,ATXN10,RGS7BP,MAP1S,TOP1,OPRM1,CRMP1,TXNRD2,CYGB,SNCG,KCNA2,SERPINI1,HSP90AA1,PPP1R1B,SLC12A2,VTI1B,GLRA1,PNOC,SNCB,NCDN,ROGDI,KLHL24,EPHA4,GPM6A,GABRA2,ATP1A3,TGFB2,ADORA1,G3BP1,EIF4A3,HTR2A,SNAP25,KCNB1,TNF,RIC3,BRINP1,DRP2,INHA,CCR2,SST,HDAC6,NDN,SIAH2,PSD2,CSNK1E,TGFB3,SMURF1,CYP17A1,BMPR1B,PPT1,CRHBP,HPCA,CX3CR1,PYCARD,AZIN2,TMEM100,KCND3,CPLX2,TACR3,GABBR1,ADNP,STMN2,ENO2 |
| 7.460e-05 | -9.50 | STAT3 (signal transducer and activator of transcription 3) | protein interactions | 6774 | 427 | 156 | 19454 | 5460 |
VEGFA,RRAS2,ETNK2,RPS9,TCEAL1,STAT1,SIAH1,MORC4,JAK2,ESR2,APEX1,LMO2,TM4SF19,MYC,CREBBP,NFYA,PIK3R3,SFN,CUL3,MBLAC2,BRCA1,HSP90AA1,SP1,COP1,SETD7,CXCR4,FOS,EP300,HSCB,PAFAH1B2,ADRB2,SRI,RP2,SSBP2,SYK,NUP62,TIRAP,TSHR,IL6ST,CDKN1A,NUFIP2,CNDP2,PIH1D1,SIN3A,OCIAD2,PGR,GSTCD,HSP90AB1,PDIA3,PIK3R1,WWP2,DLK2,YWHAG,SIAH2,TRAF6,CBL,RB1CC1,HSPB1,BCKDK,ATF3,GADD45A,JAK1,ZC3H7A,TRIM11,LASP1,LAMB2,SEMA4C,MAGEC2,ARFGAP1,RAF1,CA8,JUN,EZH2,GHR,CCR1,MOB3C,CCNF,OPTN,PELP1,CREB1,EIF2AK2,UBE2I,IL2RA,TRIM24,STAT5A,COPE,IDE,VIRMA,NMI,SRC,TRIM32,TNFAIP3,VPS39,PTPN11,IL2RB,AR,CEP70,KPNA6,IFNAR1,NIF3L1,IVNS1ABP,BICD2,UBE2H,PSMG3,RPA3,PML,BANF1,PGK1,PRKCB,ARFIP1,HDAC3,IL1RAP,GTF2I,KDM1A,FBXW7,PIK3R2,OGDHL,TMUB1,CCND1,NFYB,CAPN1,RPA2,RPRD1B,HSP90B1,STX17,FGFR1,MET,LEPR,HECTD1,STAT6,PTPN1,EEF1AKMT3,RB1,TRIM45,TES,MDM2,CDK9,MOV10,NFKB1,HDAC6,COPS5,NXT2,KPNA1,FGR,AGPAT1,CCR5,BHLHE40,IGF1R,RNF115,TP53,SOCS3,MAP2K3,SMAD1,NFE2L2,SPRY1,SRP72 |
| 7.482e-05 | -9.50 | CTNNA1 (catenin alpha 1) | protein interactions | 1495 | 325 | 123 | 19454 | 5460 |
ANKMY2,KARS1,CSNK2A1,COPS5,TDRD7,ECD,HRAS,RAC2,SEC23A,TES,CAND1,CAV1,CDC5L,CDK9,RRM1,FBP1,SMAD1,EEF1A1,EGR2,MAP2K3,CDH8,HSPA13,TFCP2,SAPCD1,DLG1,SNAP23,HSD17B10,CTNND1,PSEN1,FAM110B,MAT2A,AKT1,CARS1,CSK,CTNNBIP1,DNAJC5,AR,ARHGAP21,SPOP,MAPRE1,CTNNA1,CTTN,CFAP298,MSN,UBE2I,GSK3A,RHOJ,DUSP10,VIRMA,DYRK1A,SFRP4,FERMT2,ATG16L1,SPTBN1,CFTR,SIPA1L1,CDC42,FGFR1,STX17,JUP,FBP2,RPA2,MET,SIRT7,RPA3,YKT6,HSPA5,TAX1BP3,PRPF19,CTNNB1,IQSEC1,AGR2,RHOG,ARMC8,RASSF8,TNIK,RAB35,MAGED2,OSBP,SPTAN1,ATXN10,EGLN3,E2F4,RANBP1,PDHA1,CTNNA2,TUBB4B,PLS3,MOB3C,CCT8,RINT1,ZYX,KRAS,EPHA4,FLOT1,UBE2A,GRB10,PKP4,CUL2,PSMA4,MYC,VEZT,HSD17B3,RHOB,BRCA1,FBXW11,ILK,LSM14B,SERPINH1,NTRK3,ZNF189,LMBR1L,TSN,FBXO22,ACTB,NDUFAF4,MAP2K1,CTBP1,EIF4B,HSPA8,TXNL1,POLA2,STX7 |
| 7.485e-05 | -9.50 | SKA3 (spindle and kinetochore associated complex subunit 3) | protein interactions | 221150 | 190 | 78 | 19454 | 5460 |
COPS4,ATP5F1D,THRAP3,CTNNBL1,SKA1,BAG2,SRSF7,ZC3H7A,NUDT5,GDI2,KIF2A,PGM2L1,ANAPC13,TUBA1A,PPP2R1A,MAGEB10,CENPM,SRFBP1,SPC24,EGLN3,SPPL3,LHFPL2,COPS2,UBP1,CAMSAP2,KPNA1,MED4,SNRNP70,CENPW,YWHAH,NOL4,COPS5,YWHAG,NDC80,USP2,BAZ1B,CMSS1,FTL,ZDHHC17,SAP18,GNB4,MCMBP,MRPL57,STK38,PPP2R2C,TRA2B,KDM1A,PPIH,CCDC86,HMCES,LEMD3,CSNK1A1,TRIM36,LUC7L3,ZNF574,MAP2K1,SKA2,MRPS34,DCTN4,RPA2,PAFAH1B1,ESR2,POLR2B,ROMO1,TUBB,PHF21A,PHAX,PELO,CCNF,STUB1,MAPRE1,PTTG1,TAFAZZIN,CCDC85B,SFN,PYCR2,SEC13,NAA50 |
| 7.503e-05 | -9.50 | regulation of connective tissue replacement | biological process | GO:1905203 | 15 | 12 | 18204 | 5365 |
MIR16-1,PPARG,MIR195,ROCK1,MIR34A,PPP3CA,MIR17,MIR214,RUNX1,MIR34B,ROCK2,MIR34C |
| 7.505e-05 | -9.50 | CCNA1 (cyclin A1) | protein interactions | 8900 | 62 | 32 | 19454 | 5460 |
MCM6,TGFB1I1,PSMA2,EP300,CKS2,CDK1,H2BC1,VPS18,CDKN1A,CCNA2,CKS1B,H1-5,NFYB,TP53,CDC20,SRC,FZR1,PGR,CCAR2,MYBL2,RB1,CDKN1B,SP1,ANAPC4,H1-1,BRCA1,COPS5,SAMHD1,CTNNB1,MCM4,NFYA,USP2 |
| 7.510e-05 | -9.50 | GSR (glutathione-disulfide reductase) | protein interactions | 2936 | 91 | 43 | 19454 | 5460 |
AIFM1,FOLR1,DNAJB9,NUP35,AHSA1,HSPD1,IDH1,AGA,TF,RAF1,MVD,DDX39A,ISG15,EEF2,PIR,CRABP2,CSTPP1,ACOX1,CCNF,OPTN,ENO2,LDHA,TXNRD2,CUTA,TOMM40,CHCHD4,OAT,UBE2H,MDH1,DDX39B,DNAJC3,RPA3,BAP1,LSM12,UFL1,OXCT1,HSPA5,LAP3,CDC42,ADSS2,RPA2,PIH1D1,CNDP2 |
| 7.523e-05 | -9.49 | ARFGEF3 (ARFGEF family member 3) | protein interactions | 57221 | 75 | 37 | 19454 | 5460 |
YWHAH,LAMP3,P2RY10,GPR17,CUL3,RAB5C,LAMP2,RAB2A,FIS1,RHOG,LAMTOR1,GSK3A,ST6GAL1,LMBR1L,RAB35,ESR2,SRPK2,VIRMA,RHOJ,ARF6,HNRNPL,NPY2R,CDC42,ATG16L1,PRKCA,SIGLECL1,RAB9A,SQSTM1,IGF1R,RAB5A,VIPR1,RHOU,CD40,STX7,TACR3,PHB2,NPTN |
| 7.523e-05 | -9.49 | PAAF1 (proteasomal ATPase associated factor 1) | protein interactions | 80227 | 75 | 37 | 19454 | 5460 |
PSMB1,PSMC5,PSMB4,PSMB5,PSMA6,PTPN1,PSMB6,EGLN3,ADRM1,PSMD6,PSMD4,SSH3,USP14,PSMD1,ZFAND2B,PSMA4,PSMD3,PSMD10,PSMD7,PSMD14,CCDC92,PSMA3,GPHN,ABCF1,RPA3,PSMD12,PSMC1,SEM1,PSMA2,PSMA5,PSMA1,UBLCP1,PSMB3,PSMC4,ANXA7,PSMC3,PSMB7 |
| 7.523e-05 | -9.49 | ZC3H8 (zinc finger CCCH-type containing 8) | protein interactions | 84524 | 75 | 37 | 19454 | 5460 |
RPS16,RPS10,HNRNPL,FZR1,RPL7,RPL35,LYAR,SYNCRIP,RPS3,SRSF1,KRR1,PRR3,RPS9,CRLF3,ZCRB1,SNRNP70,RPS2,RIT1,NLRP3,H1-1,MYC,CUL3,CSNK2A1,RPL26,E4F1,H1-6,KRAS,RPL17,RPL31,THUMPD1,RPL23A,RPL26L1,ZNF574,MACROH2A2,RPSA,FGF17,RBMS2 |
| 7.523e-05 | -9.49 | JUND (JunD proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 3727 | 75 | 37 | 19454 | 5460 |
FOSL2,SMAD4,BRCA1,COP1,PLEKHO1,COPS5,TPM3,PRKCQ,MDM2,NUP35,SLC25A12,JUNB,CREB1,SMAD3,UBN1,CYTH1,CEBPG,LMNA,PPARG,NFE2L2,HINFP,TOP3B,BATF,CCND1,MLLT6,SOX2,JUN,NFE2L1,ASF1A,EGR1,MEF2A,BCL6,HIRA,ATF3,FOS,DDIT3,EP300 |
| 7.543e-05 | -9.49 | vacuole organization | biological process | GO:0007033 | 193 | 82 | 18204 | 5365 |
SMURF1,GABARAPL2,FHIP1B,CLVS2,LAMTOR1,ATG7,CHMP5,NDP,LYSET,STX12,VPS16,TRAF6,BAG3,STX17,VPS54,CHMP4C,LIPA,BECN1,ATG9A,ATG4C,MTM1,HSD17B1,PSEN1,CTSD,RAB19,ATP6V1A,TASL,CHMP2A,CLN8,ATG3,PLA2G5,MAP1LC3A,TFE3,RAB1A,CHMP2B,TMEM199,GABARAPL1,VPS18,SNAPIN,HEXB,VIPAS39,UBXN2B,TP53INP2,VPS33A,RB1CC1,ACP2,EXT1,MAP1LC3B,HSPA8,RAB14,NSFL1C,ATP6AP2,EMC6,CHMP1B,RAB1B,ATP6V1D,VPS4B,GABARAP,WDR45,TFEB,RNASEK,TMEM165,STBD1,ATG16L1,ATP6V0B,ATG4A,RAB23,CLVS1,FIG4,PPT1,LAMP2,VMP1,NPR2,HEXA,TP53INP1,TOM1,CHMP1A,TMEM106B,RAB33B,ATG101,RAB33A,VPS4A |
| 7.575e-05 | -9.49 | vesicle organization | biological process | GO:0016050 | 337 | 132 | 18204 | 5365 |
CHMP5,STX12,SNX3,CUL3,TMEM127,DNM2,YIPF4,TRAPPC1,BET1,SNX11,BLOC1S5,STX17,SYT4,AP3S2,CHMP4C,AQP11,USP8,TRAPPC6B,SAR1B,CAV1,ATP6V1A,CHMP2A,AP2M1,PLEKHF2,RAB32,VTI1B,RAB1A,CHMP2B,VPS18,BLOC1S3,TRAPPC4,SNAPIN,ATP6AP2,AP1S2,CHMP1B,VPS33A,SRGN,TRAPPC13,SQSTM1,DLG4,FASLG,SNAP25,TRAPPC2L,RNASEK,SNAP91,NECTIN2,STX8,SNAP29,ATP6V1D,SNX10,RAB22A,STX5,ARFGAP3,BLOC1S2,SEC23A,ATP6V0B,ZDHHC15,PAFAH1B1,TOM1,CHMP1A,GOSR1,VPS4A,CREB1,SURF4,GOSR2,STX10,TMCC1,VPS16,TRAPPC10,PLN,STX6,SNAP23,FHIP1B,VTA1,LAMTOR1,RAB3A,PICALM,RNF26,EXOC8,VAMP3,TRAPPC3,YIPF5,CIDEB,CAV2,PLA2G5,STX7,TSG101,SYP,STXBP1,TFG,VAMP2,HPS6,CD34,CCDC42,VIPAS39,RAB27A,HGS,ACTL9,PLEKHJ1,TRAPPC6A,GOLPH3L,RAB14,STX1A,PHETA2,VPS28,ATP6V1G1,VAMP8,WASL,CORO1C,ATP6V1C1,PLEKHF1,STX16,VPS39,STXBP6,TMED9,STX11,PREB,S100A10,SNX33,VPS4B,VAMP1,ATP6V1G2,AP1M1,KLHL12,UBAP1,VAPB,RAB11A,VAMP7,CLTRN,SEC22B,RAB29,SEC13 |
| 7.592e-05 | -9.49 | Selenium Micronutrient Network | WikiPathways | WP15 | 87 | 49 | 5310 | 1910 |
PRDX1,F2,SOD1,GPX6,TXNRD3,PNPO,CCL2,IL6,GPX2,SELENOI,LDLR,SERPINA3,SELENOS,IL1B,PRDX4,PLG,SELENOK,MSRB1,TXNRD2,SOD3,TXNRD1,SELENOO,DIO1,ALB,GPX1,GPX3,SOD2,DIO2,ICAM1,GPX4,SELENOW,HBB,SELENOF,SELENOP,TNF,PRDX3,ALOX5AP,NFKB1,SEPHS2,F7,DIO3,SELENOT,IFNG,HBA1,PRDX2,SELENOV,SELENOM,SELENON,TXN |
| 7.612e-05 | -9.48 | U2-type prespliceosome assembly | biological process | GO:1903241 | 25 | 17 | 18204 | 5365 |
SNRPD3,SF3B1,SNRPB2,SNIP1,SNRPD1,DDX46,SNRPD2,DDX42,RBMX2,SF3B4,SF3A1,SNRPG,SNRPE,SF3B5,SF3B6,SNRPA1,SNRPB |
| 7.646e-05 | -9.48 | DENND4A (DENN domain containing 4A) | protein interactions | 10260 | 83 | 40 | 19454 | 5460 |
SIPA1L1,ATG16L1,INPP5E,RAB4A,CLK1,RAB9A,TESK2,RPA3,RTKN,STX7,SRSF12,RIGI,ASB3,HSCB,SERTAD1,YWHAG,CSNK2A1,YWHAH,PCBD1,MYC,ATG9A,RAB11A,SFN,NTRK3,YWHAB,LAMTOR1,SNRNP70,YWHAZ,METTL6,GSK3A,KRT8,RAB35,CCNF,EIF4E2,STX6,EGLN3,CAV1,VIRMA,CEBPE,KCTD3 |
| 7.646e-05 | -9.48 | ARHGEF10 (Rho guanine nucleotide exchange factor 10) | protein interactions | 9639 | 83 | 40 | 19454 | 5460 |
RAB3B,FBXW7,ARHGEF39,STX7,ZYX,HSPA8,FHL3,NTRK2,BAG2,FGFR1,PTRH2,HECTD1,SART3,SSBP2,BET1,RFXANK,PRDX3,CDC42,CD2AP,STX6,VIRMA,RAB35,EEF1AKMT3,S100A8,GJA1,LAMTOR1,TIAM1,ICAM1,NTRK3,EPHA2,STYK1,UBE2H,MICB,PIK3R1,HMGA1,UBXN6,RAB11A,SFN,HSPB8,GGH |
| 7.647e-05 | -9.48 | protein localization to endoplasmic reticulum | biological process | GO:0070972 | 72 | 37 | 18204 | 5365 |
SPCS1,KDELR1,SRP14,KDELR2,SEC61A2,ZFAND2B,SEC63,BCAP29,EDEM1,SEC62,RER1,SRP54,SRPRB,DDRGK1,SRPRA,SPCS3,GPAA1,TRAM1L1,UBAC2,OS9,SEC61G,ZFAND2A,VPS54,PDIA2,SSR3,INSIG2,SGTA,FKRP,SRP72,HSPA5,SPCS2,SEC61A1,TRAM1,GABARAPL2,SEC61B,TRAM2,UBL4A |
| 7.666e-05 | -9.48 | EMD (emerin) | protein interactions | 2010 | 771 | 264 | 19454 | 5460 |
BTF3,MYC,OST4,TMEM38B,ZMPSTE24,DNAJB6,SMU1,GGT7,LMBR1L,IRF2,DLST,APEX1,ATP6AP2,SEC62,TOMM22,GOSR2,BET1,CSNK1A1,UBAC2,HDAC5,HSPA8,PCGF2,EP300,RAB5A,DDX39B,SAP18,UFL1,DDRGK1,CTNNB1,LAMP2,RAB5C,YWHAB,HSPB1,STX5,RAB35,ELK1,TUBA1A,SOX2,DNAJC25,STBD1,TAPT1,SMARCB1,ZRANB2,GLE1,TUBB4B,PDHA1,PTRH2,RAB4A,EWSR1,CYP2C9,RINT1,KRAS,TCF23,VDAC1,NUP42,GORASP2,CEP70,C9orf72,SLC25A1,ATP1A1,PDCD4,UBE2H,RC3H2,SRP54,CSNK2B,ATL1,SRC,BCCIP,RNASEH1,CDC42,GABRA1,CFTR,LEMD3,RPA2,USE1,SSR1,DERL1,RAB9A,RNF113A,TEX264,TMX2,BANF1,PML,HDAC3,COPS5,FAM20C,ADIPOR2,DHRS7,AKAP8L,AGPAT1,TUBG1,RAC2,STT3A,CAMLG,SSMEM1,COMT,TMPO,STX6,LMAN1,ARL6IP5,DNAJC1,UBIAD1,PREB,SNAP29,ZFP1,STX18,YIF1A,DHX9,PSME1,FKBP8,NUP107,H3C1,HNRNPK,SRPRB,RAB3B,KCNJ8,MCM4,VEZT,ACO2,CUL2,RAB11A,CUL3,SP1,NTRK3,SCFD1,VMP1,ILK,LMNB1,RMDN3,SNRPD1,GPR89A,SEC61B,BAD,ARF1,AVPI1,JAK2,ACTB,REEP4,TUBB,RND2,OTULINL,KCND3,TOR1AIP2,PGRMC1,NOTCH2,TMEM174,ARCN1,SLC25A3,VAPB,KLF3,ADNP,NMRAL1,HADHA,ZFP64,NUP50,STX7,PXMP2,DNAJC22,HSPB8,FATE1,DPY30,RB1CC1,MED4,HAX1,STX1A,C2CD2L,RHOG,CDK5RAP3,GJA1,CYB5A,WDR6,CBFB,ARL11,TRAF3IP3,PHB1,EGLN3,SLMAP,NUP35,LRWD1,TMEM237,SPTAN1,NUP153,FAF2,MACO1,B3GNT2,ZNF263,RAF1,CYB5B,RPN1,EZH2,STIM1,CHMP4C,SCD5,TMT1A,MCM6,UBE2A,RETREG1,SAR1B,EMC8,G3BP1,TRIM37,CTNNBIP1,HMOX2,PPP1CC,CREB3,ARFGAP3,PTEN,CCNF,SEC63,VIRMA,ST7,KLF12,RABL3,SEC22B,ARHGAP1,MET,PAK5,LMNA,SLC12A2,LSM2,TMX4,METTL14,GOLGA5,GRM2,SYVN1,RTN4,MTDH,RPA3,CHMP2B,TMEM209,LSM8,YKT6,NF2,FBXW7,HM13,LAMP3,HDAC6,TMEM199,MOV10,SLC25A46,CNN3,STYK1,OSBPL8,POR,ESYT1,HSD17B11,CDCA3,SRPRA,PTPN1,EHBP1,RCHY1,ARL10,CDK9,ZBTB2,ARF6,LBR,CCDC47,FAM169A,SRP72,IGF1R,NSDHL,SIKE1,MDC1,VRK1 |
| 7.694e-05 | -9.47 | HGS (hepatocyte growth factor-regulated tyrosine kinase substrate) | protein interactions | 9146 | 512 | 183 | 19454 | 5460 |
HNRNPK,RBCK1,TOLLIP,PSMA5,NEDD8,STX11,TP53,KBTBD4,NEFL,GOLGA7B,TFRC,SAPCD1,CD4,SNAP25,STX6,RASSF4,CSNK2A1,SMAD4,AKAP8L,TRIM10,TRIM3,RAB9A,OIP5,LITAF,TUSC2,SUMO1,ING5,FGFR1,KLF4,IL2RA,TRIM54,TRAF1,NMI,ROCK1,MED22,MAT2A,DNAJC5,EXOC5,TRIM23,SNX5,ATP1A1,SERTAD3,RINT1,FAM168A,MAPK1IP1L,EPHA4,KRAS,HNRNPDL,TFG,PAX6,ODAM,CFAP68,CSTF2T,PTRH2,HGS,SMARCB1,CEP57L1,RPRD1A,NRSN1,RANGRF,LRRC61,WWP2,SYNJ2BP,ARMC8,YWHAB,ARRDC3,HSPA8,ADRB2,BET1,NUP62,SYK,TOMM22,BORCS6,ATXN1L,DLG4,VEGFA,BST2,USP16,ESR2,TOM1L1,BRINP3,LAMTOR1,ARMC7,CRMP1,TLR4,LTBR,NTRK2,TTC4,PSMB11,TCP11L2,SMAD1,MAP1LC3B,CTLA4,CASK,SMAD3,SEC23A,PRNP,CAV1,TMCC2,FNDC11,NFKB1,MOV10,MED21,STYK1,RHOU,SQSTM1,EGFL7,NF2,LDOC1,TIMMDC1,UBA52,SPMIP6,MED30,MEST,CDR2,MET,LURAP1,SMAP2,PELP1,CCNF,UBE2I,TRIM27,SNX12,SNX3,RHOJ,JAKMIP2,SMAD5,CTTNBP2NL,UBB,IL2RB,NDUFB10,RHOBTB3,RUNX1,NRP1,EPHA2,SMAD2,TMT1A,ZYX,MRFAP1L1,BAG2,LASP1,RFC2,AHCYL1,FANCG,FLOT1,ACTN4,VAMP2,PLD3,STX12,FBXO32,PSMB4,TSG101,GJA1,SNX2,SNX1,DIRAS3,NDC80,PIK3R1,PEDS1,BCL2L1,MED4,VPS4A,G3BP2,CCND3,RNF11,CDSN,WDR77,STXBP1,LMO4,GKAP1,SDS,PNMA1,TUBB,FCHSD2,OPRM1,CUL3,DSN1,RHOB,PPP1R16A,VMP1,RIT1,EXOC8,NTRK3 |
| 7.705e-05 | -9.47 | NFATC2 (nuclear factor of activated T cells 2) | protein interactions | 4773 | 196 | 80 | 19454 | 5460 |
IRF7,KDM1A,MRPL17,MBD3,HSPA5,POLDIP2,RPA3,RFC4,HIRA,IDH3A,FOS,XRCC5,HSPA8,EP300,HADHA,RPA2,VAPB,CTBP1,ADNP,MED31,ACTL6A,NFYB,IDH3B,GTF3C4,CNP,MAFG,CEBPE,IRF2BP1,RBBP4,CBX5,VIRMA,JUNB,DEK,CREB1,UQCRC2,UBE2S,LIG3,ZMYM2,FOXP3,GTF2H2,MACROH2A1,YWHAZ,CREBBP,SMARCA5,IKZF2,SMARCE1,RUNX1,RFC5,TUFM,CSE1L,SATB1,EGR1,SSRP1,RFC3,RFC2,CHAMP1,CBX3,MTA2,SUPT5H,SOCS3,JUN,TUBA1A,PPP2R1A,EEF2,TCP1,CACYBP,AIFM1,SSBP1,ETV6,RB1,TAF9,RPL23,YWHAB,IFI16,ERCC3,IRF4,ZNF24,YWHAG,HNRNPA1,SUV39H1 |
| 7.708e-05 | -9.47 | GABA-ergic synapse | cellular component | GO:0098982 | 78 | 39 | 19108 | 5553 |
EFNA5,ABHD6,SLC6A6,SLITRK2,GABRB2,GABRA2,LRRTM2,LRRTM1,DISC1,GABRG2,SLC32A1,SST,LPAR1,SLC6A1,LHFPL4,NPY5R,GABBR1,DRD1,PLCB1,GAD2,NPY,CNR1,PHB2,FLOT1,DAG1,CDH13,KCND2,CTBP1,NLGN1,CLSTN3,NLGN2,SLITRK1,CBLN4,KCND3,PCDH17,GLRB,SLC6A11,GABRA1,GRID1 |
| 7.708e-05 | -9.47 | SMIM12 (small integral membrane protein 12) | protein interactions | 113444 | 35 | 21 | 19454 | 5460 |
PXMP2,SLC25A12,PARL,COX14,SLC25A51,VRK1,PHB2,HSD17B11,SEC61B,AKAP1,DERL1,AIFM1,TMT1A,COX4I1,SFXN1,SSR1,APOO,SEC62,TIMM29,ST7,RAB5C |
| 7.708e-05 | -9.47 | TECTB (tectorin beta) | protein interactions | 6975 | 35 | 21 | 19454 | 5460 |
PTPN1,MACROH2A1,PWP2,RAP1B,NOC4L,WDR3,ARL6IP5,RDH11,SSRP1,DAD1,MTCH2,NDUFA2,RETSAT,TOMM22,AGPAT5,TOMM40,MAK16,PTRH2,IDH2,ZMPSTE24,UTP15 |
| 7.722e-05 | -9.47 | Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | REACTOME pathways | R-HSA-6814122 | 43 | 26 | 10285 | 3229 |
TCP1,GNG12,GNG2,CCT7,MIR197,GNB1,CSNK2A1,GNB4,GNG7,CCT5,GNAI2,PDCL,RGS6,CSNK2B,GNAZ,GNGT2,GNB3,CCT8,GNG13,GNG3,GNAI3,GNG5,GNG11,GNAO1,GNG10,CCT2 |
| 7.739e-05 | -9.47 | LRBA (LPS responsive beige-like anchor protein) | protein interactions | 987 | 164 | 69 | 19454 | 5460 |
GPR17,RAB11A,MLF2,BAG3,RIC3,LAMTOR1,DNAJB6,TYROBP,NTRK3,CCNF,SLC1A1,PHF21A,PPM1M,ADRM1,FBXO22,DYRK1A,VIRMA,BET1,CFTR,INSYN2A,RND2,FGFR1,RPA2,RPA3,INPPL1,RAB9A,RAB5A,KDM1A,TUSC2,STX7,ATG9A,LAMP2,MOV10,COPS5,YWHAG,DLK2,LAMP3,YWHAH,AGR2,RHOG,NCR3LG1,STYK1,MED4,DCAF11,ARL10,HRAS,CD274,GJA1,RHOH,CCAR2,HNRNPL,CAV1,STX6,DIRAS3,TOP3B,COMTD1,TMEM126A,MAP1LC3B,RAB4A,CTLA4,TFRC,HSPA13,CYB5B,TMT1A,NTRK2,SEMA4C,RIGI,HS2ST1,ARF4 |
| 7.739e-05 | -9.47 | KIF1B (kinesin family member 1B) | protein interactions | 23095 | 164 | 69 | 19454 | 5460 |
TRAK2,EIF4E2,FUBP3,ARL10,THOC2,DIRAS3,HNRNPL,KCTD3,CSNK2A1,YWHAG,CPEB1,YWHAH,MOV10,YWHAB,TDRD7,VPS26B,DLG1,RIGI,PGM1,ACTN4,EEF1A1,DLG3,KIF1C,YTHDF2,IPO8,TOP3B,CASK,PSMC3,STARD13,GTPBP1,POLR2C,PNMA2,RAB4A,UBE2I,DLG4,PSMA6,FBLN5,ENO1,PRRC2A,VIRMA,CHP1,ACTB,SIAH1,CAV3,SFN,RSPH1,MAPRE1,RBM7,PDF,YWHAZ,PIP4K2C,BRCA1,PKNOX1,SNTA1,POMP,RAB9A,HSPA8,RTKN,RPA3,FTL,ARHGAP1,PAFAH1B1,LPXN,SPTBN1,TRIM36,CSNK1A1,PARD6A,KLC2,VIPAS39 |
| 7.750e-05 | -9.47 | TBC1D8 (TBC1 domain family member 8) | protein interactions | 11138 | 47 | 26 | 19454 | 5460 |
MUL1,SPP1,LAMTOR1,LAMP2,FAM174A,RAB11A,LAMP3,DNAJC1,RHOH,RHOJ,MRPL50,DIRAS3,LMAN1,TRAF1,CAV1,THOC2,GJA1,GSK3A,RAB4A,RND3,COMTD1,RND2,CDC42,KRAS,FLOT1,RHOU |
| 7.750e-05 | -9.47 | TEX29 (testis expressed 29) | protein interactions | 121793 | 47 | 26 | 19454 | 5460 |
GNA11,RUSF1,CLEC7A,TMEM147,RP2,FAM234A,PTS,PLAA,SMCO4,PTRH2,GOLGA5,TMX4,CMTM7,FAM3C,LEMD3,RHAG,STX10,NDFIP1,CLRN2,SLC38A2,TMEM19,GJB2,FBXO7,TMBIM6,TMEM11,TMEM190 |
| 7.750e-05 | -9.47 | ARHGEF15 (Rho guanine nucleotide exchange factor 15) | protein interactions | 22899 | 47 | 26 | 19454 | 5460 |
H1-5,CDC42,PRDX3,CDK7,DDX42,ZNF326,SF3B5,CSTPP1,FAM76B,HSD17B10,UBE3A,EPHA4,LASP1,FARSA,RPS27A,PYCR2,GORASP2,DNAJC5,BICD2,CALU,PSPC1,MOB4,MSN,PPP1R10,ATP5PD,MRPS23 |
| 7.791e-05 | -9.46 | TSN (translin) | protein interactions | 7247 | 102 | 47 | 19454 | 5460 |
TSN,APEX1,CCNF,CTNNA1,PSMA6,EIF4A3,ZBTB18,RPS20,UBE2I,HOXC4,UBE2H,NIBAN2,MYC,NTAQ1,GORASP2,ST13,GTF2I,UBE2K,NF2,UCHL3,MCMBP,RPA3,P3H1,SDCBP,RPA2,EIF4B,GIT2,ATP6V1C1,SHMT1,PPP1CB,ETF1,PRNP,SNX2,SIN3A,PTPN1,WDR12,TSNAX,MAGOH,PPP3CA,PSMD3,HNRNPF,TTC4,PFDN1,CAPZA1,PICK1,ABCE1,MSX2 |
| 7.791e-05 | -9.46 | ATP5MK (ATP synthase membrane subunit k) | protein interactions | 84833 | 102 | 47 | 19454 | 5460 |
BNIP3L,UFL1,HADHA,ARRDC3,RPA3,SLC25A3,CAV2,METTL14,SPRYD4,RPA2,MAD2L2,ESR2,VIRMA,ARMC6,MGST3,SEC61B,PTPMT1,CYB5R3,LMBR1L,CCNF,ILK,UBE2H,TAFAZZIN,USP14,ATP5F1A,BTF3,CUL3,VDAC1,CHCHD2,SFXN1,NDUFA4,MAP1B,SLC25A5,SLC25A20,CYB5R1,SOX2,UBL4A,EGLN3,EIF2B5,FZR1,OCIAD2,PHB1,ESYT1,DDRGK1,SPATS2L,ATP5MG,PRDX1 |
| 7.797e-05 | -9.46 | cellular response to decreased oxygen levels | biological process | GO:0036294 | 146 | 65 | 18204 | 5365 |
MIR106B,STC1,MDM2,TP53,MYC,SFRP1,MIR126,MIR34A,KCNMB1,ACAA2,MT3,EGLN3,MIEF1,MGARP,LMNA,HILPDA,FAM162A,STUB1,SRC,NOP53,KCND2,AKT1,AIFM1,NDNF,PHB2,CLCA1,NKX3-1,ATF4,MIR140,NGB,NFE2L2,FOS,GAD2,PMAIP1,MIR210,VEGFA,TERT,MAP1LC3A,EGLN2,ADO,PRKCE,BNIP3L,BAD,MIR448,MSTN,MIR17,CPEB1,MIR214,TERC,MIR20A,CDKN1B,ERO1A,SUV39H1,CBL,RGCC,HP1BP3,NDP,AQP3,SLC29A1,PGK1,BECN1,PPARG,PICK1,CCNA2,MIR146A |
| 7.814e-05 | -9.46 | regulation of post-translational protein modification | biological process | GO:1901873 | 250 | 102 | 18204 | 5365 |
TRIM21,PELI1,SQSTM1,HSP90AA1,HUWE1,BAG2,BCL10,ANGPT1,RWDD3,PPIB,COPS2,CDC20,PPIA,FZR1,CAMLG,UBB,COPS7A,RCHY1,FLCN,SVBP,UBE3A,MAGEC2,SPOPL,UBE2S,BEX3,DNAJB2,RPS2,RPL23,UBE2I,UFL1,COPS4,UBE2B,TSPO,HSPA5,CDKN1B,HDAC3,CUL3,HSP90AB1,RBCK1,EGR1,IVNS1ABP,TRIM44,NMI,NSMCE3,MAD2L2,CAV1,TICAM1,TANK,GABARAP,FBXW7,ISG15,RPS7,NOP53,VPS28,AKT1,SIAH2,MINAR1,CDK5,UBE2V1,GCLC,FAM107A,HMG20A,STUB1,PTPN22,UBE2V2,COPS7B,RPS3,BIRC2,CRTAP,UBE2L3,TNFAIP3,CTNNB1,CHP1,MIR101-1,SIRT7,MUL1,DCUN1D5,UBE2D1,UBE2N,ARRDC3,TOPORS,PIAS1,PLAA,SKP1,TRAF6,NDFIP1,TOLLIP,COPS5,DERL1,P3H1,DCUN1D3,CDK5RAP3,GSK3A,WBP1L,PRKCE,CRY1,KDM1A,PSMD10,PHF23,MAD2L1,DCUN1D1,PTEN |
| 7.821e-05 | -9.46 | DZIP3 (DAZ interacting zinc finger protein 3) | protein interactions | 9666 | 127 | 56 | 19454 | 5460 |
SPTAN1,NUF2,HMG20A,UBE2N,FUBP3,RPRD1A,TSG101,BECN1,H2AC4,UBE2D1,MED4,NDC80,UBE2E2,ZNF24,ZCCHC10,MOV10,MIR29C,TOLLIP,TOM1,HNRNPF,PCGF3,AP1M1,TFPT,ZC3H7A,TRIM21,MIR20A,RNF181,TP53,YTHDF2,MAX,UBE2V1,MATR3,PRRC2A,UBE2V2,UBE2I,PHF21A,ZMYM2,BRCA1,UBE2E3,MYO6,UBE2H,CCHCR1,RUNX1,OIP5,YTHDF1,UBE2K,KDM1A,UBE2D3,RNF11,AKAP1,BIRC2,GOLGA5,GIT2,UBE2W,CCND1,TOM1L2 |
| 7.821e-05 | -9.46 | PPIL1 (peptidylprolyl isomerase like 1) | protein interactions | 51645 | 127 | 56 | 19454 | 5460 |
NUDT19,RAF1,SSRP1,PPWD1,CDC40,H3C1,LSM4,EWSR1,SNIP1,LHX2,TST,GSTO1,HNRNPA1,SAT2,COPS5,PMM2,CWC15,CDC5L,ESD,RBM42,TOP1,BUD31,FZR1,RAC2,SYNCRIP,FKBP1A,TFIP11,LSM2,RPA2,LMNA,PPP1R8,WDR83,DDIT4L,WDR77,SPDYE4,SF3A1,LNX2,STAU1,RBM22,UFL1,ELOF1,SF3B1,CWF19L1,RPA3,SNRPA,UBE2H,RIT1,SNRPB,MYC,ESR2,SRPK2,GADD45G,AKR1C2,CMBL,GCFC2,CCNF |
| 7.821e-05 | -9.46 | RRM1 (ribonucleotide reductase catalytic subunit M1) | protein interactions | 6240 | 127 | 56 | 19454 | 5460 |
TXN,RAB14,RPL35,GPR37,LRIF1,RPL10,DYRK1A,CCNF,CTNNA1,CTTN,ZNF655,PFDN2,UBE2H,RIT1,MYC,CUL3,PPP1CC,HSCB,TMEM177,RPA3,EP300,SQSTM1,RPA2,PAK2,HEXIM1,PIH1D1,CDC42,FZR1,SUMO2,MDM2,EGLN3,DHX15,CD274,LCMT1,DNAJC7,PDIA3,EMC4,GTF2E1,PPIB,YWHAG,XPO1,COPS5,ARL5B,G3BP1,KRAS,CSE1L,IMMP2L,CCT8,EMC2,CBX3,OTULIN,RNF126,CMPK1,RRM1,MAP1LC3B,EEF2 |
| 7.867e-05 | -9.45 | COX14 (cytochrome c oxidase assembly factor COX14) | protein interactions | 84987 | 144 | 62 | 19454 | 5460 |
SLC25A12,COX14,NDUFS8,TOMM70,CDCA3,COX4I1,EHBP1,TIMM8B,STT3A,PTPN1,WDR6,SRPRA,HAX1,SMIM12,AK2,COX5A,KARS1,CLPX,ARF4,ETFA,USP30,CLPB,FAM136A,NDUFS3,NDUFS6,STIM1,NUDT19,TMEM31,TIMM8A,MTARC2,NDUFA2,ETFB,MRPL11,SNAP29,CCDC47,NDUFAF4,CHCHD3,ATP5F1B,COPE,DLST,TACO1,CALU,KIAA1191,PYCR2,PYCR1,COX6B1,C9orf72,YKT6,NDUFS2,AKAP1,HADHA,MAVS,COX17,EXD2,NDUFA5,SAMM50,LMNA,VAPB,ATP5PO,TIMM13,MTX2,TOMM22 |
| 7.916e-05 | -9.44 | Prpf8 (pre-mRNA processing factor 8) | protein interactions | 192159 | 52 | 28 | 19454 | 5460 |
SNRNP40,SNRPD3,DHX15,CWC15,CDC5L,RSRC1,SNRPD2,SNRPD1,ECD,DDX23,PRPF19,SNRPB,PRPF31,RUVBL1,TSSC4,LSM4,LSM8,SNRPG,PRPF4,NCDN,PPIH,RUVBL2,USP39,SNRPE,TFIP11,DHX38,SNRNP27,CD2BP2 |
| 7.916e-05 | -9.44 | TMEM222 (transmembrane protein 222) | protein interactions | 84065 | 52 | 28 | 19454 | 5460 |
TMX2,PTGES,RTN4,ERG28,BSCL2,KRAS,LMNA,TMEM14B,CLRN1,GNAI3,PRSS23,ELOVL4,SSMEM1,COMT,RETREG3,ARF6,RNASEK,CRB3,FAM174A,RAB2A,MOV10,CREB3,RUNX1,LAMP3,NCR3LG1,STX1A,ZDHHC15,UPK1A |
| 7.918e-05 | -9.44 | regulation of toll-like receptor 4 signaling pathway | biological process | GO:0034143 | 36 | 22 | 18204 | 5365 |
TRIM32,TNFAIP3,TAX1BP1,MIR200C,MIR708,TIRAP,IFI35,MIR149,LILRA2,FLOT1,BPIFB1,MIR140,PELI1,SQSTM1,MIR146A,NINJ1,PIK3R1,ZNRF1,PTPN22,MIR20A,CD14,TICAM2 |
| 7.944e-05 | -9.44 | negative regulation of protein transport | biological process | GO:0051224 | 119 | 55 | 18204 | 5365 |
DERL2,IL12A,ANGPT1,CDK5,IL1B,KCNJ11,DPH3,UBE2G2,PPP3CA,CD200,ADTRP,PKIA,OPRM1,DRD3,PTPN11,CHP1,IL12B,NDUFAF2,WWP2,UBAC2,SVIP,RAB23,KCNB1,ADIPOQ,ENY2,ACVR1C,UCP2,ERLEC1,JAGN1,GNAO1,CCN3,ERP29,TXN,NEO1,SFRP1,CSK,RSAD2,MIR148A,SNX3,SUFU,NDFIP1,PKIG,GHRL,SNX12,GNAZ,UFM1,MIR146A,HADH,SYT4,OS9,SUMO1,LYPLA1,FKBP1B,CHGA,CD36 |
| 8.027e-05 | -9.43 | sulfur compound metabolic process | biological process | GO:0006790 | 311 | 123 | 18204 | 5365 |
GGT7,IDH1,ACACA,ELOVL1,B3GNT2,SLC25A10,EXTL2,AKR1A1,GLCE,THTPA,SLC19A3,HS3ST1,GSTM5,ELOVL6,MPST,HPGDS,GSTT1,GSTT2B,CHPF,CHST7,SOD1,ACAT1,ACOT8,CHST11,MVD,STAT5A,TST,MMACHC,TECR,CSGALNACT2,G6PD,NDP,FMO3,CHST2,GSTM4,PDHA1,TPST1,B4GAT1,LIAS,GPX1,SLC1A1,GPAM,SLC1A2,GSTP1,PPT1,DPEP1,SLC7A11,CHST9,SULT1A3,GPC1,PDHB,MAT2A,ABHD14B,GSTM2,FMO1,GLRX2,SLC5A6,GCLC,ST3GAL1,HEXB,FAR2,GSTA2,ACOT6,GSTA4,NUDT19,HMGCS1,NDST3,EDNRA,B4GALT4,ELOVL7,HACD1,NUDT7,SLC19A2,PAPSS2,HS3ST3A1,ST3GAL2,ARL6IP5,HS2ST1,ELOVL4,GSTK1,GSTA1,MGST2,TKTL1,GSTO1,MTAP,BPNT2,CDO1,GSTO2,SOD2,DLST,SLC25A1,CSGALNACT1,HEXA,NDST1,AHCYL1,CHST13,SUCLG2,HACD2,GLO1,MMUT,GSTM3,ELOVL3,ACSL4,FITM2,CHAC2,UGDH,GLYAT,ST3GAL4,GAL3ST4,SULT1B1,CHPF2,UST,GNMT,DLAT,GHR,ACSS2,ANGPT1,GGTA1,CHST1,HS3ST5,EXT1,MTHFD2L,MAT2B |
| 8.032e-05 | -9.43 | positive regulation of protein phosphorylation | biological process | GO:0001934 | 574 | 211 | 18204 | 5365 |
FGF10,GH1,TXN,MT3,CCND3,IGF1,KRAS,PDCD10,MAP2K3,PIK3R3,TGFB2,OSBP,IFNA13,SLCO3A1,TLR6,CCR7,TNFSF18,PROX1,ADTRP,ADRB2,GREM1,RAP2B,TNFSF15,AKT1,IL1B,DVL2,GSK3A,MAP2K1,FCGR1A,IL5,MMD,JAK2,FGF1,NRP1,CCND1,TGFBR2,IL2,PAK2,MIR221,DIRAS2,CARTPT,CRKL,DLG3,ODAM,FAS,KIT,SOX9,FERMT2,ERP29,TOM1L1,IL6,MOB3B,IFNA10,CD86,PPIA,MMP9,DUSP19,CCL5,UBE2K,EPHA4,TLR3,IL12B,PRNP,IL6ST,CSF2,HAX1,HSP90AA1,CLIP3,MAP3K12,FLOT1,VEGFC,PSRC1,MIF,IL12A,HTR2A,TPD52L1,UCN,CD36,CD80,HSP90AB1,AGAP2,EFNA5,PRKAG1,MAD2L2,SMYD3,IFNB1,CAV1,TAB1,MAVS,CLEC6A,LCP2,EHD4,HBEGF,TNIK,MIR30B,CD4,IFNA2,MIR21,PSEN1,MOB3C,IFNK,HDAC3,EMP2,CREBL2,RGCC,NPTN,IL4,RAP1A,TRAF2,CX3CR1,LACRT,TRIM6,RPS3,PHB1,YES1,TFRC,DDRGK1,MAP3K11,FGF3,FGF17,TNF,ADIPOQ,RAF1,CX3CL1,ROCK2,FBXW7,NKX3-1,HDAC6,PRR5L,CAB39,HRAS,AGER,STK11,FGF7,SYK,FGF16,RALB,CD40,TESK1,ILK,PIH1D1,STRADB,ADNP,TNFRSF14,PSMD10,MAP2K6,CHI3L1,HCLS1,ARL2BP,CDKN1A,CLDN3,F2,DIRAS1,CCL19,XRCC5,TBK1,TRAF6,RARRES2,ACVR1,CACUL1,IL21,CAMP,LEPR,IL13,CCNY,DIPK2A,STK4,NTF4,IFNG,TP53,TAB2,TCIM,PHB2,PTPN11,PIK3CG,DLG4,LEP,SQSTM1,APLNR,TLR4,FGFR1,P2RY1,MIR26B,CSH1,RB1CC1,IL18,GHR,SRC,FGF22,PTPN1,ANGPT1,RAP2C,IL23A,SEMA7A,VEGFA,IL3,EZH2,CHRNA7,IL15,EPO,IL34,FGF23,NTRK3,NTRK2,NBN,CAMK1,RAP2A,CDKN1B,GPNMB,OSM,FAXDC2 |
| 8.041e-05 | -9.43 | TERC (telomerase RNA component) | protein interactions | 7012 | 10 | 9 | 19454 | 5460 |
TERT,RUVBL2,RUVBL1,RIGI,SMN1,VIRMA,TERC,NHP2,DKC1 |
| 8.125e-05 | -9.42 | RAP1B (RAP1B, member of RAS oncogene family) | protein interactions | 5908 | 170 | 71 | 19454 | 5460 |
CDC42,RGL1,WRAP53,RPA2,GHITM,RASL10A,CNDP2,CAV2,BAP1,NGRN,RPA3,VIPR1,HSPA8,RAB5A,PDHB,GRPR,STX7,ZDHHC17,RGS2,RGL2,CABCOCO1,RAB11A,KIAA1191,RHOB,UQCRC2,OPTN,RHOJ,LRIF1,ATP6AP2,DDAH2,USP5,ESR2,KBTBD4,RAF1,CENPM,TP53,E2F4,EZH2,KRIT1,RAB4A,ILF2,ITGB8,STX12,IL20RB,FAF1,SHISA2,EMC2,TRIM37,TOLLIP,RAB8B,MOV10,MRPS35,TLE1,RAB5C,HDAC6,PCED1A,TM4SF18,TPGS2,AGPAT1,DICER1,RAB35,HRAS,PLPPR1,RAC2,FZR1,ARF6,RPL35A,RHOH,DERL2,ZBTB2,CCT7 |
| 8.137e-05 | -9.42 | PDCD6IP (programmed cell death 6 interacting protein) | protein interactions | 10015 | 211 | 85 | 19454 | 5460 |
HAPSTR1,HSD17B10,KRAS,G3BP1,TOLLIP,UBE2A,AHCYL1,SAR1B,TFG,TOP3B,TUBA1A,DRD1,MAP1LC3B,PIR,EZH2,PDHA1,CHMP4C,CBFB,TSG101,MAP1LC3A,TES,HNRNPL,CGAS,SUMO2,MIF,RAMP3,ESD,CNTROB,DPP4,IFI16,WWP2,YWHAG,YWHAH,CTNNB1,TUBG1,AGR2,COTL1,CXCR1,BAP1,SOD1,SIRT7,HSPA8,ARRDC3,IL1B,NF2,SRI,STAU1,RNF11,VPS28,SPR,TPT1,CD2AP,SDCBP,RPA2,VPS4B,LRRN1,DRD3,PIH1D1,LMBR1L,CCNF,ENO1,DLST,SCAMP2,PRDX2,YES1,TAB1,TUBB,UQCRQ,SRC,MYC,GSTK1,CUL3,BTF3,BAG3,SPOP,GLOD4,NEURL2,TRIM23,STK24,BRCA1,NRP1,HTRA2,VMP1,UBE2H,RIT1 |
| 8.141e-05 | -9.42 | ABT1 (activator of basal transcription 1) | protein interactions | 29777 | 381 | 141 | 19454 | 5460 |
MRPS11,PICK1,RPL31,UTP25,CA10,CDCA7L,SAP30,TRMT1L,RAF1,RPL18,RPS11,EZH2,GLE1,RPLP2,SRSF1,WDR6,STK3,LYAR,RPS10,STK4,NGDN,MRPL9,RAB5C,SAV1,MRPS35,ZBED4,RSBN1L,MRPS26,DROSHA,DCAF5,ZCCHC9,CCDC86,SF3B1,NMRAL1,NGRN,MRPS7,MRPL57,NOP53,STAU1,YTHDF1,APOBEC3C,MRPS18A,RPL37A,ZNF22,RPL19,KBTBD6,SYNE4,RPF1,RPL35,RPL7L1,MRPL23,MRPL16,ZNF668,RIOK2,MYC,APOBEC3B,NSA2,RPS5,MRPS25,ZCRB1,FTSJ3,FYTTD1,MRPS18B,RPL3,RPL23A,NKRF,MRPL52,RPL17,RIGI,MRPS18C,SRSF12,NOC4L,PAK1IP1,MRPS33,RPL15,APOBEC3D,MRPL47,MRPL11,STRBP,SRP72,TOPORS,ADAMTS1,RBM34,LLPH,KRR1,MRPS9,SRP14,NAP1L5,MRPL24,MRPS23,SURF6,DKC1,PRNP,CAND1,RPS16,APOBEC3F,E4F1,HDAC6,CSNK2A1,MOV10,RPL10A,CDK12,NOL12,RPS2,MPHOSPH10,CCDC106,PRPF4,RPL27,AATF,CXXC1,BRIX1,RPL4,MRPL41,NPM3,DGCR8,RPS15,PIP5K1A,ZNF770,RPLP0,RPL26L1,ZNF574,TFB1M,MRPS34,CSNK2B,PHAX,PRKRA,FGFBP1,TRIM27,RPS3,RSL24D1,RPP25,RPL13A,RPP25L,MRPS21,PPP1CC,CEP70,RPL7A,RPF2,CDKN2AIP,RRP7A,MRPS16 |
| 8.156e-05 | -9.41 | secretory granule | cellular component | GO:0030141 | 897 | 312 | 19108 | 5553 |
EEF2,CST3,TF,ANXA7,SFTPA1,RETN,LACRT,NME2,RAP2B,EXOC3,TMBIM1,PDYN,COTL1,CCT2,VEGFA,DEGS1,HUWE1,RHOG,TSSK1B,PSMC3,COMMD9,RAB2A,CXCL1,KLK6,SLC18B1,SPACDR,CTSA,CD46,NCSTN,CYSTM1,B4GALT1,SCG2,CCT8,ADRB1,PRDX6,CD9,ALB,CTSD,PSMA5,RND2,STX7,TUBB4B,CTNNA1,MIF,IL1B,SCG3,LAMTOR3,FAF2,MAGED2,PSEN1,BST2,HEXB,SERPINB1,RAB14,DNASE1L1,SNAP29,TEX264,CHGA,SERPINI1,VAMP8,CAV1,TOLLIP,LAMP2,LILRA3,GTPBP2,PSMB1,CFAP119,STOM,VEZT,SLC2A3,CDC42,FTL,PYGB,RNASET2,KLK5,SVIP,CYB5R3,VDAC2,PGM1,ANXA4,VAMP2,SCG5,ARMC8,SNX10,SELENOP,RAB18,VTI1B,PSMD6,CD36,TRAPPC1,HSP90AA1,SYT2,IDH1,CYRIB,CAV2,ICA1,FGL2,SNAP25,SV2B,NPPC,SYPL1,SERPINA1,ILF2,RAP1A,TGFB2,CD14,SELL,PRSS37,TLR2,B2M,SERPINA3,COMMD3,CRHBP,PSMD14,PLG,PPFIA3,PDAP1,HBB,DBH,DNAJC3,PAFAH1B2,OLR1,SPTAN1,SRP14,GLIPR1,PROS1,ATP6V1A,TGFB3,NDUFC2,S100A11,SST,CXCR1,TIMP1,NEU1,ATP6V1E2,TMEM95,PRDX4,ACTL9,PRCP,CARTPT,TICAM2,HCRT,TMEM190,DPEP3,HMOX2,ITGAV,VAMP3,CYB561,CMTM6,FTH1,TYROBP,CLCA1,CD63,PYCARD,ACTR2,RAB9B,AP1M1,MME,TMT1A,XRCC5,SDCBP,SURF4,PCSK2,TREML1,CAND1,RAB4A,CHI3L1,TMX3,HSP90AB1,FCAR,ACTR1B,ATP6V1D,RAB3D,RAB6A,TNFRSF1B,DYNLL1,VWF,RARRES2,HSPD1,SFTPC,CD58,PPIA,PSMD1,NPY,CD47,DNAJC5,PAK2,FCGR2A,S100A8,CYB5R1,ADRB2,ROCK1,PSMA2,PSMD3,NUDT1,DSN1,TUBB,SYT4,HMGB1,ORMDL3,NPC2,EEF1A1,HP,AGA,PSMB7,CAMP,BPIFA2,OLA1,LGALS3,CAPN1,JUP,CPE,FGR,TMEM179B,CD59,FAM3C,TRIM36,IGF1,PLAC8,LYZL4,TMSB4X,SLC30A5,CLU,ACTN4,SERPINB6,VAMP1,ENPP4,MOXD1,LYZ,TCP1,RAP2C,GHRL,LYZL6,SRI,SRGN,GGH,CTSB,LHFPL2,CAB39,CMA1,CALR,SNAPIN,CDC37L1,RAB13,YPEL5,LAMTOR2,RACGAP1,SERPINB10,VEGFC,RAB5C,PGRMC1,GSTP1,ATG7,CSTB,MMP9,SNAP23,SERPINA5,ATP6AP2,RAB3A,PSMD12,STXBP1,TTR,FCER1G,CPNE1,HEXA,CSNK2B,HSPA8,PATE4,STBD1,LAMP3,RAP1B,NFKB1,KCNJ11,ATP8A1,KLK9,GOLGA7,PLEKHO2,GDI2,PLCB2,KLK3,PNP,RAB37,GZMK,TMEM30A,TNFAIP6,IZUMO1,TIMP3,SYNGR1,PADI2,HEBP2,ABHD2,CTSC,GCA,LAMTOR1,TOM1,PSMD7,TOR4A,RAB31,PGAM1,KIT,GNAI2,SIGLEC5,BRI3,PCYOX1L,HILPDA,TBC1D10C,RAB27A,FABP5,SLPI,CALML5,APEH,VAMP7 |
| 8.177e-05 | -9.41 | cellular response to dsRNA | biological process | GO:0071359 | 23 | 16 | 18204 | 5365 |
FLOT1,CGAS,PDE12,IRF3,NFKB1,MUL1,DHX9,MAVS,RALB,PQBP1,TLR3,IFNB1,CAV1,RIGI,GRIA1,IFIH1 |
| 8.198e-05 | -9.41 | IKK complex recruitment mediated by RIP1 | REACTOME pathways | R-HSA-937041 | 24 | 17 | 10285 | 3229 |
TICAM1,UBE2D3,LY96,UBE2V1,RPS27A,SARM1,TLR4,UBA52,UBB,BIRC2,UBE2D1,IKBKB,TICAM2,TLR3,TRAF6,CD14,UBE2N |
| 8.203e-05 | -9.41 | DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8) | protein interactions | 22826 | 214 | 86 | 19454 | 5460 |
RPL35A,UBE2N,SRP14,SYNCRIP,ELOC,RBM17,RPL17,MEPCE,FBXO25,EGR1,NOC4L,H3C1,NEDD8,HUWE1,DHX9,EMC2,DDX42,SURF4,CBX3,WBP11,RAP1A,TBK1,SRPK2,MACROH2A1,RPS12,GTF2A1,ZNF330,SF3B6,RPL7A,RPF2,HSPA5,RPL4,WDR3,PPM1G,RPA3,HELLS,DDX46,RPLP0,E2F6,LMNA,RPA2,SF3A1,DHX15,CNTROB,RPL7,SNRPD3,SNRPA1,TTC9C,EED,BTF3L4,HNRNPA1,RPL6,HMGA1,ROCK2,KRAS,G3BP1,EWSR1,TOP2B,HNRNPA2B1,HSPD1,RPS23,SF3B5,EIF1AX,GDI2,E2F4,APEX1,SNRPB2,ERH,CBX5,PPP5C,RBBP4,SF3B4,SNRPD2,RIT1,RCL1,FTSJ3,H1-10,SNRPB,PMPCA,MYC,COIL,YTHDF1,PMAIP1,SF3B1,PYM1,MFAP1 |
| 8.208e-05 | -9.41 | NARS1 (asparaginyl-tRNA synthetase 1) | protein interactions | 4677 | 130 | 57 | 19454 | 5460 |
SCLT1,RARS1,EIF4B,JUP,RPA2,HCST,SNRNP27,ATG16L1,HSPB2,NUP50,BAP1,RPA3,XRCC5,SIRT7,DNAJB6,UBE2H,RIT1,CIRBP,CD226,FTSJ3,SAMHD1,USP14,NCAPG2,MYC,CABCOCO1,GFUS,CUL2,GRB10,LILRA3,PAPOLA,RABIF,VIRMA,TRMT11,GANAB,BAD,CCNF,OPTN,UBE2S,EZH2,JUN,GTF2E2,RAF1,CENPM,DUSP19,CBLL1,PRPS1,KRAS,S100A10,RPL24,KARS1,IFI16,HNRNPL,RPL35A,SUMO2,OSBP,SEC23A,PTPN1 |
| 8.225e-05 | -9.41 | PDK3 (pyruvate dehydrogenase kinase 3) | protein interactions | 5165 | 116 | 52 | 19454 | 5460 |
FASTKD5,COX8A,HINT2,CCT8,HSPD1,GFM2,EIF1AX,PDHA1,UBR7,METTL15,TULP3,MRPL11,CCT5,RMND1,CCT7,HSP90AB1,MIF,TCP1,GATD3,YBEY,HDHD5,SSBP1,ECD,MTRF1,GRSF1,DNLZ,PDHB,HSCB,GFM1,DLAT,EXD2,DVL2,RPA3,MTRES1,FDFT1,RPA2,ZC3H14,PGRMC1,ACAP2,VIRMA,ESR2,STAT5A,CCDC90B,STUB1,TACO1,HSP90AA1,CCT2,TUFM,PMPCA,CUL3,AUH,MTG2 |
| 8.230e-05 | -9.41 | CWF19L1 (CWF19 like cell cycle control factor 1) | protein interactions | 55280 | 70 | 35 | 19454 | 5460 |
SNRPB,PRPF19,MYC,HNRNPC,ELAVL2,YWHAB,UBE2H,YWHAZ,METAP2,TOM1L1,WIF1,CDC5L,SNRPB2,DBR1,SNRPA1,RALYL,ATG16L1,E2F4,ILF2,SNRPE,CBX3,LMNA,RPA2,RAP2A,BAG2,THBS3,EP300,RPA3,SNRPG,PTGES3,KRAS,H3C1,UFL1,TSSC4,FBXW7 |
| 8.230e-05 | -9.41 | CAVIN3 (caveolae associated protein 3) | protein interactions | 112464 | 70 | 35 | 19454 | 5460 |
XPO1,GPRASP2,TPM3,CEP70,TUFM,MYC,FGFR1OP2,RAB5C,RPS26,CALU,CCT2,RHOB,BRCA1,TMPO,ATP6AP2,MRPL23,MATR3,RPS16,SPTAN1,H2AX,YIPF5,TIMM8A,SPTBN1,NUP62,SNAP29,STBD1,ILF2,TFIP11,MRPL49,MRFAP1,TMEM147,PC,MRFAP1L1,SFXN1,FBXW7 |
| 8.238e-05 | -9.40 | ATP6V1C1 (ATPase H+ transporting V1 subunit C1) | protein interactions | 528 | 94 | 44 | 19454 | 5460 |
HSPA8,ARFIP1,RPA3,TXNDC17,VTA1,ATP6V1G1,KRAS,PHB2,GPM6A,ATP6V1G2,PPP2R1A,ATP6V1C1,SHMT1,PAK2,PTP4A2,RPA2,UBAC2,SSR1,TYMS,GTF2A1,TLDC2,CDCA3,ATP6V1A,CTTN,IDE,ATP6AP2,ESR2,RAB14,STAT1,MGST3,SNX2,SNX1,TSN,TENT5C,ATG7,MOV10,MRPS35,CBL,PSMG3,RIT1,ATP6V1D,FAS,CISD1,IVNS1ABP |
| 8.238e-05 | -9.40 | NAA50 (N-alpha-acetyltransferase 50, NatE catalytic subunit) | protein interactions | 80218 | 94 | 44 | 19454 | 5460 |
TIMM8B,AIFM1,NIPA2,WIF1,PRELID1,FERMT2,NAA11,MBD5,HYPK,ACTB,RPL35A,HNRNPL,HDAC6,ARL6IP6,MMUT,COPS5,MYC,RIT1,DNAJB6,OSGEP,POU5F1,HNRNPD,DNAJC7,CYP1A1,HSD17B10,HSPA8,BHLHE40,SFXN1,RPA3,GOLGA7,HNRNPDL,RNF26,PHB2,KRAS,SNRNP27,ANAPC13,GCLC,TANK,CENPM,NAA16,NAA15,OTX2,RPA2,SKA3 |
| 8.261e-05 | -9.40 | LSM | pfam domains | PF01423 | 19 | 14 | 17795 | 5224 |
SNRPG,LSM6,LSM10,LSM2,SNRPD3,SNRPE,SNRPB,SNRPD1,SNRPN,LSM5,LSM8,LSM4,SNRPD2,LSM3 |
| 8.297e-05 | -9.40 | Degradation of beta-catenin by the destruction complex | REACTOME pathways | R-HSA-195253 | 83 | 43 | 10285 | 3229 |
CTBP1,UBA52,PPP2R1A,UBB,PSMD14,PSMD7,PSMD10,PSME1,SKP1,PPP2R5E,PSMB6,PSMA2,PSMB3,PSMA4,PSMA5,PSMB10,PSMB11,PSMC5,PSMA3,PSMB5,PSMC4,PPP2R5A,PSMB7,PSMD3,PSMB1,RPS27A,PSMD4,CTNNB1,PSMC3,PSMA1,SEM1,PSMB9,PSME2,PSMB4,PSMD6,PSMB2,PSMD1,CSNK1A1,PSMA6,PPP2CB,TLE1,PSMC1,PSMD12 |
| 8.318e-05 | -9.39 | ERCC6 (ERCC excision repair 6, chromatin remodeling factor) | protein interactions | 2074 | 220 | 88 | 19454 | 5460 |
ATP5PO,UQCRC1,SUMO1,RNF11,MBD3,GRPEL1,MRPL20,HSPA5,RPS15,GTF2I,SF3B1,DDX5,HELLS,XRCC5,PRPF4,PML,NBN,BAX,ZBTB38,MAPRE1,FYTTD1,RBBP8,BRCA1,MRPS25,PSMD1,RPL39,NONO,OGG1,RPS29,SMARCA5,MYC,UQCRQ,POLR2B,CLIC4,RPL10,VIRMA,COPE,CTSB,FBXO22,RBBP4,PSMC5,SNRPD1,CSNK2B,MRPL13,UBE2I,TACO1,EIF4A3,POLR2D,MTA2,POLR2C,POLR2G,PNMA2,ACTR2,GTF2E2,MTA3,MRPL11,CCT5,E2F4,TP53,MRPL47,PSMD12,PTGES3,COPS4,RBBP7,H3C1,PCNA,MRPS18B,SLC39A7,RPS24,ATF3,TOP2B,MRPS26,DDX1,RHOG,DDX23,H2AC4,EIF3D,PSMD3,BAZ1B,MDM2,PPIA,CAND1,MRPL50,TOP1,SUMO2,CORO1C,SSBP1,PSMB5 |
| 8.332e-05 | -9.39 | DNAJB1 (DnaJ heat shock protein family (Hsp40) member B1) | protein interactions | 3337 | 280 | 108 | 19454 | 5460 |
ABCG2,PEA15,SPOP,DNAJC5,DNAJC8,MLF1,AKT1,VIRMA,RAB14,IRF2BP1,CTSB,GSK3A,STUB1,CCNF,E2F6,FGFR1,LMNA,RPA2,CDK7,CFTR,EDF1,ATG16L1,POLDIP2,HSPA5,GRPEL1,STK38,PSEN2,PML,BAP1,SOD1,RPA3,DNAJC7,TUBG1,SPP1,DAG1,PLEKHO1,CAV1,MDM2,FZR1,RAP1B,SRP14,TMSB10,TP53,PTGES3,FKBP8,PPDPF,OLA1,DNAJC30,HUWE1,PDE12,SFXN1,ZNF451,DNAJB6,BRCA1,LMNB1,BLVRA,BRMS1,BAG3,MLF2,SFN,CUL3,MYC,ERH,ESR2,CBX5,GPR37,EFHD2,LMBR1L,PPT1,ATP5PO,STXBP1,ETF1,PGRMC1,MTX2,STAU1,HSPA8,SPECC1L,DNAJC3,NQO1,MED4,HAX1,YWHAG,HNRNPA1,YWHAH,RAB5C,EGLN3,RPS10,TTC9C,MAGED2,TSG101,PRCC,RAB35,OTULIN,PPID,CTSA,SMNDC1,GDI2,EZH2,VAMP2,CYP2C8,ISG15,FAF2,PCGF6,RAD21,BAG2,EWSR1,DNAJB4,BCKDK |
| 8.354e-05 | -9.39 | cellular response to exogenous dsRNA | biological process | GO:0071360 | 17 | 13 | 18204 | 5365 |
FLOT1,CGAS,IRF3,MUL1,MAVS,DHX9,RALB,TLR3,PQBP1,IFNB1,CAV1,RIGI,IFIH1 |
| 8.391e-05 | -9.39 | positive regulation of interleukin-12 production | biological process | GO:0032735 | 43 | 25 | 18204 | 5365 |
HMGB1,TLR9,SYK,PLCB1,TRAF6,IRF1,TLR2,HSPD1,CD40,CCR7,CCL19,AGER,CD40LG,LEP,TLR4,IDO1,TLR3,IFNG,TIRAP,IL12B,LTB,IL23A,CLEC7A,IRF8,CD36 |
| 8.398e-05 | -9.38 | RSL24D1 (ribosomal L24 domain containing 1) | protein interactions | 51187 | 105 | 48 | 19454 | 5460 |
ZNF574,RPLP0,RNF113A,NPM3,DGCR8,RPL4,LSM8,MYC,RPL7A,FBXO7,ZNF668,LMNB1,PEA15,H1-1,NSA2,RIT1,FGFBP1,RPL37A,PRKRA,MCPH1,RPL13A,RPL35,RPL7L1,RPL10,RPL19,ESR2,MAGEB10,MAK16,RPL15,RPL31,SNIP1,PPAN,FGF3,RPL23A,EWSR1,RPL3,KRAS,RPL28,IFI16,CDC23,RPL8,KRR1,SRSF1,MRTO4,RPS10,CAND1,LYAR,SURF6 |
| 8.404e-05 | -9.38 | NEIL1 (nei like DNA glycosylase 1) | protein interactions | 79661 | 274 | 106 | 19454 | 5460 |
NOP16,MYC,MRPL16,ZNF668,FTSJ3,ZCRB1,NSA2,RPS5,PARP2,ZNF22,MRPL13,RPL37A,RPF1,RPL7L1,ZCCHC7,MRPL23,APEX1,APOBEC3C,MRPS18A,NGRN,CCDC86,SF3B1,STAU1,NOP53,MRPS7,MRPS35,DDX50,NGDN,MRPL9,WDR12,ARMC8,MRPS26,RBM5,DUSP6,RPL8,RPL9,HP1BP3,RPLP2,RPL7,HNRNPL,ZNF397,MAK16,GLE1,RPS24,MRPS11,TRIM26,H1-6,RPS4X,MRPS17,RPF2,RPS17,LIG3,RPS3,PRKRA,CSNK2B,MRPS28,RPP25L,SRPK2,RSL24D1,RPS14,MRPL10,MRPS34,ZNF770,RPLP0,RPL26L1,ZNF574,MRPL17,RPS15,AATF,BRIX1,MOV10,CMSS1,APOBEC3F,CSNK2A1,MPHOSPH10,POLB,RPL10A,NOL12,RPS2,KRR1,MRPS9,RPS16,ZNF7,CDC5L,MRPS23,SURF6,DKC1,MRPL47,H2AX,RBM34,RAD1,MRPL51,SRP72,NKRF,MRPL52,RPL3,MRPS18B,RPL23A,HAPSTR1,IMP4,CTNNBL1,PAK1IP1,MRPS33,RPL17,MRPS18C,MEPCE |
| 8.434e-05 | -9.38 | E5 (transforming protein E5) | protein interactions | 1489077 | 150 | 64 | 19454 | 5460 |
SLC30A7,FZD6,GGT7,SEC61B,PIGK,TECR,ABHD12,RPL13A,KDSR,ATP1A1,ENDOD1,RABAC1,TAPBP,MAVS,RTN4,ATP2C1,APMAP,DAD1,RER1,SSR3,PHB2,TRAM1,SEC62,RABL3,TM9SF1,FAM8A1,ATP5PO,STOM,MMP14,UBAC2,GJA1,STT3A,PTPN1,LAPTM4A,HACD3,TMPO,ERLIN1,SELENON,CAV1,DERL2,HM13,QPCTL,TOR4A,PDIA3,TMEM184C,SLC2A1,TMX3,SEC11A,GPAA1,NDUFA4,ATP5PF,ATP2B4,RAB18,ERLEC1,TMEM33,SRPRB,YIPF4,FAF2,YIPF3,ERLIN2,MTCH2,PLD3,SURF4,TMEM165 |
| 8.451e-05 | -9.38 | Fc epsilon receptor (FCERI) signaling | REACTOME pathways | R-HSA-2454202 | 372 | 151 | 10285 | 3229 |
WDR83,UBA52,SYK,FGF22,RAF1,RASGRP2,TNRC6C,RAP1B,PRKCQ,KRAS,MAP2K1,MOV10,NFKBIA,FGF10,PIK3AP1,PSMD10,FRS3,DUSP9,SRC,PIP5K1A,PPP2R5E,SPTAN1,PSMB3,PEBP1,FCER1G,PAQR3,MET,NFKB1,LAT2,PSMA5,PTEN,FGF23,TAB1,YWHAB,MDM2,PPP2R5A,FGF1,DUSP6,IL2RG,PIK3R2,ICOS,IL3,RPS27A,SPRED1,PSMD4,PHB1,TP53,PSMC3,PSMA1,CD86,SEM1,DUSP1,RASGRP3,SHC1,IKBKB,PSMB4,PAK2,PSMB2,PSMD1,PEA15,AKT3,PSMA6,AKT1,PIK3CA,IL5,HRAS,GAB1,PPP2CB,KIT,LAMTOR2,PIP4K2C,UBE2V1,VWF,CUL3,PSMC1,IER3,UBE2N,TAB2,BCL10,FGF16,LAMTOR3,CAMK2G,IL2RB,PPP2R1A,LCP2,UBB,PSMD14,PTPN11,FGF17,CD80,PSMD7,PPP5C,AGO1,SPTBN1,ANGPT1,PSME1,SKP1,PSMA2,ITK,FBXW11,PSMB6,BRAP,CSK,CD28,DLG4,PSMA4,PSMB10,FGFR1,PSMC5,IL2,JUN,PSMB11,VAV2,PSMB5,PSMA3,FOS,PSMC4,CDKN1B,PSMB7,JAK2,PSMD3,CREB1,PSMB1,AHCYL1,PIK3R1,NEFL,DUSP10,PPP3CA,BAD,MAP3K11,GSK3A,GRAP2,SPRED2,IL2RA,PSMB9,UBE2D1,PSME2,FGF3,HBEGF,TRAF6,PSMD6,SHC3,RAP1A,AKT2,FGF7,JAK1,MAPK10,PSMD12,CSF2,PIK3R3,CDKN1A |
| 8.452e-05 | -9.38 | positive regulation of innate immune response | biological process | GO:0045089 | 288 | 115 | 18204 | 5365 |
TRIM3,MYD88,PQBP1,SH2D1A,IRAK4,IFIH1,IFNK,TLR9,ZNRF1,RTN4,IFI16,TLR8,LILRA2,CLEC6A,IKBKB,TAB1,MAVS,TRIM15,NMI,TLR1,CAV1,IFNB1,TYROBP,TICAM1,RIGI,SIN3A,ATAT1,POLR3F,CD36,SRC,IL12A,CD274,HSPD1,BCL10,MATR3,FLOT1,PELI1,NONO,RNF34,NECTIN2,TLR4,PHB2,TOMM70,HEXIM1,HSP90AA1,USP15,IRF3,POLR3B,UBE2K,TLR3,IL12B,CCL5,NEK7,CLEC7A,RSAD2,IL21,NLRP3,TRAF6,TLR2,CD14,TICAM2,TLR10,XRCC5,TBK1,KLRD1,PLSCR1,TMEM126A,MAPKAPK3,NINJ1,IFI35,BECN1,TIFA,PAK2,TLR5,PLA2G5,TIRAP,TASL,MAP2K6,LSM14A,PSPC1,TLR7,IRF7,NLRP6,CGAS,OAS1,TRAF3IP3,LACC1,KCNJ8,PRKCE,DHX9,OTULIN,HMGB1,CD1D,SYK,MBL2,NLRP1,PTPN22,PYCARD,CREBBP,CD226,TRIM5,NCR3,TLR6,CLPB,FCN2,EP300,NFKBIA,TNF,TRIM62,TRIM6,LY96,PHB1,KLRC2,TNFAIP3,PIK3AP1 |
| 8.463e-05 | -9.38 | RET (ret proto-oncogene) | protein interactions | 5979 | 268 | 104 | 19454 | 5460 |
SNAP29,DOK5,CCDC47,DDX39A,H3C1,TF,TTC4,SRPRB,CTNND1,SMN1,STX18,EMC2,IGF1R,HSD17B10,SHC1,ESYT1,OSBPL8,LMAN1,TMPO,DOK6,PTPN1,SRPRA,SYNCRIP,AIP,CAMLG,SEC23A,TES,CDCA3,PDCL,LEMD3,TXNL4A,SEC22B,YKT6,CERS2,NF2,B2M,TTR,PIK3R2,CHMP2B,CLU,HSPA5,LCP1,SDF2L1,ARFGAP3,PEA15,NRP1,OAT,C9orf72,CCNB1,PTPN11,FBXO7,GORASP2,SRC,GAB1,VAMP3,SMAP2,ALB,EPCAM,NUDT19,STIM1,CFAP36,CRKL,HGS,MACO1,NUDCD3,FAF2,PCDH19,NCSTN,TULP3,PFDN1,MYO1B,CDK5RAP3,NCK1,HNRNPD,CBL,PIK3R1,SHC3,CTNNB1,DDRGK1,CACYBP,WDR44,PTK7,PTGDS,SPINT2,STX5,VAPB,GTF2IRD1,NOTCH2,EMC1,DUSP26,BMPR1A,RABAC1,CKB,SCFD1,HSP90AA1,CRMP1,NIBAN2,VEZT,GRB10,TIMP1,MB21D2,SIAH1,CHP1,DOK4 |
| 8.475e-05 | -9.38 | SEC23A (SEC23 homolog A, COPII coat complex component) | protein interactions | 10484 | 232 | 92 | 19454 | 5460 |
PHB1,FBXO32,DNM2,OSBP,SUMO2,SUMO3,NUF2,ERLIN1,FATE1,XPO1,AGR2,EWSR1,ROCK2,EPHA4,PSMA1,SAR1B,AP1M1,FASLG,RAF1,TOP3B,SOX2,GFPT1,CHMP4C,STMN2,KLHL12,HGS,S100A6,LMBR1L,USP16,UBE2V2,CUL3,CUL2,MYC,SAMHD1,BRCA1,DCAF4,SERPINH1,NTRK3,MIA2,TTC1,HSPA8,STAU1,UNC45A,BET1,GLRA2,YIPF5,CSNK1A1,PIH1D1,EIF4B,ARMC1,CD274,PTPN1,CAND1,DCUN1D1,PLGRKT,MINAR1,CDC5L,TMEM45B,SLC25A46,EMC4,STYK1,FAF1,IGF1R,NEDD8,RIGI,TNRC6C,INSIG2,TP53,STRBP,WBP11,UBE2B,FURIN,CTNNA1,EIF4A3,CCNF,STUB1,SGTA,MSN,SNX3,VIRMA,DYRK1A,SEC13,PSMB2,CARS1,UBE2H,SIRT7,RPA3,BAP1,SLC7A1,CFTR,FGFR1,RPA2 |
| 8.502e-05 | -9.37 | amide metabolic process | biological process | GO:0043603 | 385 | 148 | 18204 | 5365 |
XPNPEP1,MTHFD2L,PNP,PSENEN,REN,DLAT,ACSS2,GGTA1,ATP6AP2,PCSK2,PSEN2,B3GALT1,SPTSSB,BACE1,GLYAT,ATF4,ELOVL3,GSTM3,ASMT,CHAC2,ACSL4,FITM2,MMUT,ABHD4,SUCLG2,GLO1,HACD2,ST6GAL1,NANP,HEXA,SOD2,DLST,DEGS1,SLC25A1,GNPDA1,HTRA2,ORMDL1,AGK,GSTO2,ST3GAL5,MGST2,GSTA1,B4GALT3,SLC30A5,SLC25A32,GSTO1,ST8SIA4,TLCD3B,ENPEP,ELOVL4,GSTK1,IDE,CYP4F22,NUDT7,PSEN1,ARL6IP5,B4GALT6,B3GALT4,ST3GAL2,CLN8,GNPDA2,SLC25A42,B4GALT4,HACD1,ELOVL7,FURIN,NUDT19,CMAS,NCSTN,CMA1,HMGCS1,ST3GAL1,AASDHPPT,NEU1,GSTA4,PLAAT5,HEXB,FAR2,SMPD2,ACOT6,GSTA2,GCLC,ORMDL3,SLC5A6,MME,GAL3ST1,SCG5,GSTM2,CERK,DYRK1A,GLRX2,PLA2G15,PDHB,ITGB8,APH1A,DPEP1,CERS6,NT5C2,GALC,APEH,PLAAT3,SHMT1,SLC7A11,SGMS1,CERS2,PPT1,OSBP,ST6GALNAC3,GPAM,SLC1A1,GSTP1,SLC1A2,AANAT,GPX1,FA2H,SGMS2,GSTM4,MTHFS,PDHA1,CPE,G6PD,MMACHC,TECR,NDP,BECN1,YIPF5,DPP4,URAD,SOD1,ACAT1,MVD,ACOT8,FOLR1,GSTT1,GSTT2B,ELOVL6,CYP2C9,HPGDS,ARG2,B3GALT2,GSTM5,SPTSSA,ACER3,GGT7,UGCG,ELOVL1,IDH1,ACACA |
| 8.520e-05 | -9.37 | TOP2B (DNA topoisomerase II beta) | protein interactions | 7155 | 238 | 94 | 19454 | 5460 |
RPA2,LMNA,METTL14,CDC42,ATG16L1,SUMO1,HDAC3,HMGB1,FBXW7,NUCKS1,RPA3,PML,NLE1,PDCD4,NAPA,DNAJC8,AR,VIRMA,SRPK2,RHOJ,CSNK2B,UBE2I,CCNF,PSPC1,ZNF330,HBP1,NUPR1,CBX3,IK,NECAP1,TP53,PTGES3,H3C1,VRK1,SEPTIN7,ZNF451,TOPBP1,BRD3,MED27,BECN1,SNRNP70,ZMYND11,TLE1,POLE3,ZBTB2,RPS16,TOP1,H2AZ1,PPARG,RND2,ACTL6A,COIL,TRIM52,G3BP2,ASB3,FTL,STAU1,EP300,FOXD3,XRCC5,RHOB,DCAF4,BRCA1,PSMD14,SMARCE1,MYC,OTUD6A,RPL10,APEX1,ACTB,SNRNP40,DLST,MTA2,SMARCB1,RHOBTB1,SNRPE,EZH2,CHMP4C,NCSTN,ISG15,SSRP1,RPS24,RPL31,TOP2B,DDX23,XPO1,IFI16,HMGA1,BAZ1B,WWP2,SUMO2,RHOH,PSMB5,SRSF1 |
| 8.535e-05 | -9.37 | XIAP (X-linked inhibitor of apoptosis) | protein interactions | 331 | 241 | 95 | 19454 | 5460 |
TUFM,NTAQ1,CCNB1,TRIM32,AKT1,PTTG1,PTEN,UBE2I,STUB1,UBB,UBE2L3,MAP3K3,CDC42,UBE2W,CDK1,PPIH,SQSTM1,PML,IRF3,TPM3,XAF1,ERCC3,BMPR1B,SSX2IP,BCL10,UBE2N,SRPRA,AIFM1,CCL17,MDM2,HTRA1,UBE2V1,KBTBD4,TBK1,BIRC5,TAB2,BMPR2,FAF1,STRADB,RIGI,TOLLIP,SERTAD1,TTC23,CASP4,RFC5,CXCL1,HNRNPC,CUL3,HTRA2,BAX,BOLA1,BRCA1,CCT2,GCC1,RPS9,FAIM,USP5,UBE2V2,SIAH1,TAB1,DYNLL1,PRDX2,PRDX3,CRYAB,BIRC2,ACTMAP,SKP1,BOLA2B,PHB2,UBE2D3,UCHL3,HNRNPA1,YWHAG,UBE2E2,TRIM8,SIVA1,PPM1K,HAX1,CASP12,TRAF6,UBE2D1,ATP6V1A,PHB1,DNM2,HSP90AB1,HNRNPL,EEF2,TRAF2,CCS,RAF1,CKS1B,OSTM1,UBE2A,ACVR1B,TRIM37 |
| 8.540e-05 | -9.37 | PARVA (parvin alpha) | protein interactions | 55742 | 78 | 38 | 19454 | 5460 |
ILK,CRMP1,CCNB1,RAB11A,CHMP2A,CDC5L,ZBTB2,FERMT2,OSBP,PPAT,ACTB,RAC2,FBXO32,CREB1,HRAS,TBC1D17,ZRANB2,LIMS2,MAP2K1,NFE2L1,SOX2,OTUD6B,TANK,LPXN,DPH5,ATG16L1,UGP2,GCA,FBXW7,EMC8,KRAS,UBE3A,HNRNPH2,HSPB2,PML,HNMT,RPA3,CMTR2 |
| 8.545e-05 | -9.37 | MRPL38 (mitochondrial ribosomal protein L38) | protein interactions | 64978 | 244 | 96 | 19454 | 5460 |
GATD3,SRSF10,RPL6,MTRF1,TRA2A,HNRNPA1,MRPL9,RHOG,MRPL18,ARMC8,MRPS26,MAEA,HSPD1,HINT2,KRAS,FLOT1,ENKD1,OTULIN,MTG1,TACO1,MRPL13,MRPL23,BTG3,PRRC2A,ESR2,RPL19,RPL10,PRMT6,PMPCA,AUH,MTG2,BAG3,MRPL16,TSEN54,RIT1,EXD2,NGRN,MRPL57,MYOZ3,TMEM177,TRA2B,HSCB,CMAS,LYG2,RANBP10,DUSP14,RPL27A,MRPL12,MRPS18A,FOXS1,HRAS,MRPS9,SSBP1,MRPL50,CGAS,PRNP,ARF6,PPP1R18,ZBTB2,MRPL24,MALSU1,GRSF1,CSNK2A1,SNRNP70,TMEM70,TSNAX,MRPL52,ERG28,RPL17,MRPL11,TP53,MRPL47,METTL15,AURKAIP1,MRPL51,MRPL49,ILF2,MID1IP1,MRPL53,GSTK1,TUFM,UBE2H,GFM1,SQSTM1,MRPL40,MRPL41,MRPL17,MRPL20,NHP2,MPV17,RBMS2,MRPL10,CHMP1A,RPA2,MTRES1,HAUS2 |
| 8.545e-05 | -9.37 | ASH2L (ASH2 like, histone lysine methyltransferase complex subunit) | protein interactions | 9070 | 244 | 96 | 19454 | 5460 |
HCFC2,BAP1,HSPA5,POLDIP2,CXXC1,NUCKS1,FBXW7,ZSCAN1,PSMC4,DYRK2,WWP1,PICALM,ZMYM6,RPA2,PSMC5,CSNK2B,PELP1,SMURF1,BUB3,AR,PPP1CC,RUNX1,TRIM32,CDC73,SMAD2,PIP4K2C,MDC1,PAGR1,KPNA2,KDM4B,H3C1,RPL15,SMAD1,TP53,RAD23B,MSRB3,CCDC69,PCMTD2,LDLR,H2AZ1,PTPN1,ELOC,CSNK2A1,USP15,TSNAX,KPNA1,EP300,COX17,HSPA8,FOS,SNRPA,PPARG,PRMT5,RPL37A,RAN,DLST,S100A6,ESR2,POLR2B,TUBB,RBBP4,RBM15B,KANSL3,PRPF31,RHEB,TIMP1,CUL3,MYC,RIT1,SP1,HSP90AA1,DCAF4,BRCA1,RERE,PAX6,RUVBL1,HNRNPF,RBBP7,SAP30,ELF1,SOX2,E2F4,CSNK1E,EZH2,WDR82,SIN3A,DYNC1I2,CCAR2,CTNNB1,XPO1,DPY30,TAF7,HMGA1,LHX2,SMAD9,KDM2A |
| 8.550e-05 | -9.37 | FBXO32 (F-box protein 32) | protein interactions | 114907 | 247 | 97 | 19454 | 5460 |
GMPPA,CDK9,ILVBL,KRR1,STT3A,MRPS9,SEC23A,SURF4,UAP1,PPME1,DUSP1,LBR,TTC4,NOC4L,FARSA,NUP107,AKAP12,VPS16,CTNND1,VTA1,FBXO25,NAE1,EHD4,SLC25A10,PC,CLPB,BICD2,IGF2BP1,DHPS,MORF4L1,SMARCA5,HSPA14,GMPS,CFL1,DEK,CSTF3,EIF2AK2,MACROH2A1,SEC61A1,EIF2B3,DCTN4,KLF4,ACACA,PPP1R8,PSMC4,SAP30BP,SMC4,WDR3,BRIX1,HELLS,NCDN,PRIM2,MAVS,HMCES,KDM2A,MRPS35,BABAM1,CLPX,ATXN10,LYAR,FAM98A,LRWD1,FBXO32,FUBP3,DNM2,TSG101,HGS,ACO1,NUP37,ERLIN2,RPL29,FAF2,GNL1,TFG,COPS4,PSMD12,VPS26B,UBE3A,PRPSAP1,ARMT1,PMPCA,TBCE,NIBAN2,SAMHD1,NCKAP1,CPSF1,SMU1,PAK2,CTBP1,PLAA,TOR1AIP2,CDKN1A,IDH3B,SERPINB6,MCMBP,SKP1,UNC45A |
| 8.588e-05 | -9.36 | HTATSF1 (HIV-1 Tat specific factor 1) | protein interactions | 27336 | 133 | 58 | 19454 | 5460 |
HDAC6,CSNK2A1,COPS5,TCEANC2,SNRNP70,MAP1LC3A,RCHY1,FEZ1,CDK9,SNRPA1,CD2BP2,H2AX,TP53,SUPT5H,SNRPE,EZH2,CBX3,DNAJC2,EWSR1,TCOF1,SRSF4,SNRPG,SNRPB,NIBAN2,CUL3,STK11,UBE2H,RBM7,FYTTD1,SNRPD2,SEC61B,GTF2F2,SF3B6,CCNF,PELP1,ESR2,VIRMA,SRPK2,SNRPB2,MED17,SNRNP40,SUPT4H1,SF3A1,SNRPN,PIP5K1A,DYRK2,HEXIM1,UBE2M,CSNK1A1,RPA2,SF3B1,HSPA8,PGK1,CLK1,NUP50,RPA3,SLU7,COIL |
| 8.588e-05 | -9.36 | PPP4C (protein phosphatase 4 catalytic subunit) | protein interactions | 5531 | 133 | 58 | 19454 | 5460 |
STK24,GLYATL3,CCT2,HTRA2,RIT1,CUL3,FBXO22,SLC25A31,TMSB4X,SELENOT,SF3B6,SF3B4,RPA2,TPT1,FBXO42,SUPT4H1,PPP2R2C,UBE2D3,HDAC3,RPA3,RNF113A,STK26,SF3B1,TRAF6,UBXN10,TUBG1,PRPF19,NFKB1,ATG7,COPS5,XPO1,TCP1,MIF,SPPL3,HNRNPL,CAND1,CCT7,CDC5L,PPP2CB,LCMT1,IGBP1,PPME1,SF3B5,SUPT5H,CCT5,TP53,DHX38,TRMT1L,PPP2R1A,JUN,EEF1A1,KRAS,MSH6,IMMP2L,SMN1,MCM6,CCT8,TLR4 |
| 8.588e-05 | -9.36 | ZMYM3 (zinc finger MYM-type containing 3) | protein interactions | 9203 | 133 | 58 | 19454 | 5460 |
GPR17,CUL3,MYC,GGH,USP14,BRCA1,ZNF330,MIDEAS,LMBR1L,MACROH2A1,PHF21A,ZMYM2,DYNLL1,RBBP4,ESR2,CBX5,UBB,SUMO1,PCK2,KLF12,GTF2IRD1,RPA2,KLF3,SIRT7,PML,RPA3,LPAR1,NUCKS1,KDM1A,HDAC3,GTF2I,HMGA1,MOV10,YWHAG,NOL4,HDAC6,H2AC4,TGFB3,H2AZ1,SIN3A,THOC2,CDK6,GRM1,SUMO2,ZBTB2,ATP5PB,BUD23,ZMYM4,SPG21,H2AX,CBX3,MTA2,ATP5PF,GPHA2,ZSCAN5A,RBBP7,PAX6,FOXP4 |
| 8.605e-05 | -9.36 | Mitochondrial translation elongation | REACTOME pathways | R-HSA-5389840 | 88 | 45 | 10285 | 3229 |
MRPL52,MRPS9,MRPS17,MRPL36,MRPL34,MRPL10,MRPS7,MRPS16,MRPS11,MRPS35,MRPS34,MRPL51,MRPS25,KGD4,MRPL18,TUFM,MRPL12,MRPL17,MRPL24,MRPS21,MRPL40,MRPL47,MRPS18B,MRPL50,MRPL41,MRPL33,MRPL20,MRPS28,MRPS23,MRPS33,MRPL23,MRPL49,MRPS26,GFM1,MRPS18C,AURKAIP1,CHCHD1,MRPL22,MRPL9,MRPL13,MRPL16,MRPL57,MRPL53,MRPS18A,MRPL11 |
| 8.671e-05 | -9.35 | Chemokine_b/g/d | interpro domains | IPR039809 | 41 | 24 | 18521 | 5414 |
CX3CL1,CCL3,CCL17,CCL19,CCL18,CCL11,CXCL10,CXCL13,CCL24,CCL1,CXCL3,CCL25,CCL8,CXCL8,CXCL9,XCL1,CCL2,CCL20,CCL4L1,CXCL12,CCL5,CCL21,CCL23,CXCL1 |
| 8.704e-05 | -9.35 | GNAI1 (G protein subunit alpha i1) | protein interactions | 2770 | 153 | 65 | 19454 | 5460 |
RGS10,PGR,STK3,DUSP6,BCL2L1,CBL,DPP4,CMKLR2,PSMD3,DDRGK1,GNG2,HDAC6,CD81,CNR1,BCKDK,CCR5,GPSM3,IGF1R,GNG5,NGB,TFCP2,PDE6D,FURIN,GNAI3,E2F4,RAF1,TOP3B,HTR2A,GNG10,GNG3,CD47,GNAI2,GNB1,PPP5C,CCNF,S1PR4,PTEN,PCP2,RGS5,GNAO1,CRHR1,NRP1,OPRM1,AR,BTF3,THAP7,ADRB2,RASD1,EMC1,GNB4,RGS19,RPA3,CXCR4,VIPR1,NMRAL1,DRD3,METTL14,FGFR1,RPA2,PAK5,GNG7,KLHL3,DUSP22,GABRA1,TSHR |
| 8.714e-05 | -9.35 | SUMO3 (small ubiquitin like modifier 3) | protein interactions | 6612 | 119 | 53 | 19454 | 5460 |
ZMYM2,SENP5,UBE2I,ENO2,RAN,ZBTB33,ENO1,ESR2,TAGLN2,ZCCHC12,DRAP1,UFD1,CSK,CUL3,MAPRE1,FAM221A,PCGF2,INPPL1,MAPKAPK3,FOS,PML,PIAS1,ZBTB39,UCHL3,TTR,IRF7,CDKN1A,UBE2M,ANXA7,SEC23A,MTAP,EGLN3,CAV1,SUMO2,COPS5,XPO1,MOV10,ISYNA1,SNRNP70,EWSR1,TAGLN3,UBE3A,ZNF451,PFDN1,FKBP2,PAX6,SMN1,JUN,RAF1,RANBP1,TP53,RAD23B,RNF8 |
| 8.750e-05 | -9.34 | MAPK cascade | biological process | GO:0000165 | 222 | 92 | 18204 | 5365 |
BRAP,TLR3,MAP3K21,PAFAH1B1,PEA15,CRYAB,DUSP19,MYC,MAP3K3,MEF2A,FLCN,SCG2,ADRA1A,CDK1,FGFR1,ITGAV,CCL3,TLR4,STK3,SPRY1,BTN2A2,CCL11,MAP3K12,FGF23,IKBKB,ARHGEF6,RCE1,PPP1CB,CAV1,MEF2C,NF2,CAV3,CD36,MYD88,IRAK4,HACD3,YWHAZ,SBK2,RASGRP3,PTGER4,TNIK,IGFBP3,MAP2K3,SMAD3,RAF1,KARS1,KRAS,MAP3K11,TNF,TF,OXTR,FGF10,CTNNB1,RHBDD3,NPR2,CCM2,IL1B,STUB1,HRAS,MAPK10,DUSP10,GRB10,SMAD4,MAPK4,MAPKAPK5,RIT2,MAP2K6,INPPL1,SMAD1,PPP5C,DUSP6,TLR7,TBC1D10C,IGFBP4,FGF13,STRADB,MAP3K14,PPP1CC,NFKB1,PRKCE,MAP2K1,KCNJ8,MAP1LC3A,CCR5,SOX9,CD2AP,DUSP9,TRIB1,AR,MAPKAPK3,CRKL,BECN1 |
| 8.799e-05 | -9.34 | Beta-catenin independent WNT signaling | REACTOME pathways | R-HSA-3858494 | 149 | 69 | 10285 | 3229 |
PSMA3,PSMB5,PDE6A,PSMC4,PSMD3,PSMB7,PSMB1,AP2A1,PSMB6,PSMA2,GNG13,PSMB3,PLCB2,PLCB1,GNG5,PSMA4,GNG10,PSMC5,PSMB11,PSMA5,PSMB10,MOV10,GNG12,PSMD7,GNG2,FZD4,PSMD10,AGO1,PSME1,UBA52,PRKCA,GNB1,UBB,TNRC6C,PSMD14,GNG7,DAAM1,PSMD12,PSMC1,FZD6,PRKCB,GNGT2,GNB3,DVL2,AP2M1,PSMB2,PSMD1,PARD6A,PSMA6,GNG3,SMURF1,GNG11,AP2S1,GNAO1,PSMB9,SEM1,RAC2,PSME2,PSMD6,PSMB4,FZD3,RPS27A,PSMD4,PPP3CA,MIR937,PSMC3,CTNNB1,GNB4,PSMA1 |
| 8.819e-05 | -9.34 | regulation of cytokine production involved in inflammatory response | biological process | GO:1900015 | 80 | 40 | 18204 | 5365 |
MIR197,EZH2,PDCD4,BAP1,KPNA6,MIR338,MIR16-1,MIR129-1,IL6,CLEC7A,MIR125A,TLR3,MIR675,MACIR,CHID1,TICAM1,GPSM3,IL17F,TNF,PLD3,MIR378A,MIR21,PPARA,MIR140,PYCARD,MIR146A,TLR4,LEP,LILRB4,MIR98,MIR324,IRF3,MIR221,TLR6,F2,MYD88,MIR222,MIR136,IL1R2,MIR17 |
| 8.942e-05 | -9.32 | intracellular chemical homeostasis | biological process | GO:0055082 | 581 | 213 | 18204 | 5365 |
ATP6V1D,PRNP,GRM1,MT1X,SLC1A3,RNASEK,CCL3,VPS33A,KCNJ2,ATP6AP2,TRPC1,CNNM4,CA2,HTR2A,LAMP2,IGF1R,BAX,ATP1B3,MYC,FTH1,FITM2,STOML2,CCL5,ATP6V0B,KCNB1,UBE3A,RMDN3,SLC39A9,AQP11,CCDC186,FXN,ATP1A3,AQP4,MIR146A,PSEN1,ATP2C1,RTN4,ORMDL1,PCK2,SLC38A3,NPTN,SMAD2,TPT1,CMA1,FKBP1B,SNAPIN,CAV3,IREB2,KCTD17,CAV1,ATP6V1A,PAX6,SIN3A,FTL,EDNRA,PRND,FTHL17,ACO1,SMAD4,DRD3,MT1E,SLC31A1,PPP3CA,P2RY4,GCLC,ATP6V1G1,GSTP1,ATP5F1B,BAK1,VDR,RHAG,SLC1A1,TWNK,GPX1,TF,MT3,UCP2,CALR,BOK,CHP1,IL1A,ATP1B1,FIS1,CNR1,PICALM,CARTPT,SLC8A1,SOD1,ATP1A2,GRIA1,RGN,MIR320A,XBP1,SLC30A7,NDFIP1,FRRS1,PRKCB,CCR1,LACC1,NUCKS1,SLC4A8,ATP2B4,CAV2,CCL8,SLC25A23,CCL11,COX11,LRRC8A,FASLG,CYB561,SLC4A10,ATF4,TM9SF4,TMEM165,KCNJ11,P2RY1,ADORA1,CIAO3,RHCG,NEO1,MIR15A,SLC39A7,SOD2,PIK3CA,CACNB2,SLC39A13,ARF1,ICAM1,CLIC4,STIM1,OPRK1,SV2B,CYP7A1,CCDC22,FUNDC2,FATE1,PIK3R2,PIK3R1,CCDC47,CCL1,SLC30A5,B2M,MIRLET7G,TMEM199,HEXB,SLC41A1,CHRNA7,MT1A,MAIP1,FGF23,S100A8,FOXA3,SELENOT,SMDT1,SLC22A17,AGER,COX19,ORMDL3,KCNMA1,CD40,TMBIM6,CCL23,HFE,CXCL12,RAB11B,ATP1A1,CYBRD1,TMEM106B,SELENOK,TFRC,CLTRN,SLC7A11,VAPB,STC1,PPT1,RAF1,SLC39A10,SMAD3,ISCU,ATP6V0E1,CCR2,BOLA2B,F2,VPS54,CCL19,SLC25A27,GRM2,MT2A,SLC29A1,NPTX1,PLN,TMEM203,DMPK,CFTR,BOLA3,SLC12A2,BOLA1,TRA2B,CACNB4,MIR16-1,MT1M,SRI,ADNP,LRRC8D,GPR89A,DISC1,SLC11A2,GLRX5,TASL,NHERF1,NPPC,PML,HSP90B1 |
| 8.949e-05 | -9.32 | CPLX1 (complexin 1) | protein interactions | 10815 | 40 | 23 | 19454 | 5460 |
TAGLN2,SNAP25,PRNP,PPIA,UBE2V2,VAMP3,SGTA,POMP,STX1A,OPRM1,PFDN5,DPY30,JPT1,GLO1,NEDD8,GINS3,SNRPA,HSPA8,NUBP2,CPLX2,VAMP2,UBE2B,AGTRAP |
| 8.949e-05 | -9.32 | SBF2 (SET binding factor 2) | protein interactions | 81846 | 40 | 23 | 19454 | 5460 |
FBXO7,XPO1,FBXW11,AK2,HNRNPD,EEF1AKMT3,SYNCRIP,RAB35,SNRPD2,TXNDC12,HNRNPL,VIRMA,G6PD,TP53,TOP3B,MACROH2A2,PIH1D1,MTMR2,PPM1G,FHL3,FBXW7,SLC31A1,DCTPP1 |
| 8.949e-05 | -9.32 | NDUFAF8 (NADH:ubiquinone oxidoreductase complex assembly factor 8) | protein interactions | 284184 | 40 | 23 | 19454 | 5460 |
SLC16A1,ATP5F1E,CLPB,HNRNPA2B1,TUBA1B,ATP5PD,POLDIP2,STARD7,CHCHD2,SPINDOC,CPT2,TUBB,DHRS4,HNRNPA1,WDR77,ATP5PB,PMPCA,RPL6,STOML2,MRPS35,NDUFA5,ATP5PO,NDUFS3 |
| 8.960e-05 | -9.32 | NUDT19 (nudix hydrolase 19) | protein interactions | 390916 | 136 | 59 | 19454 | 5460 |
UBE2H,FXN,EPHA2,NTRK3,LAMTOR1,TUFM,AK3,PMPCA,AUH,MTG2,NDUFAF4,TXN,ANAPC2,CCDC90B,CCNF,IRF2,FKBP1A,FGFR1,RPA2,GABARAPL2,CRYZ,NT5C3A,TOMM20,STAU1,PHB2,AKAP1,SQSTM1,CSTB,EXD2,PTRHD1,RPA3,HAX1,DNAJC7,AK2,GRSF1,NPC2,CEP19,COX14,LRRC61,GATD3,YBEY,SSBP1,AIFM1,FABP5,MSRB3,POLR2C,VAC14,PDHA1,VPS33A,MTCH2,MRPL11,TOP3B,IMMP2L,FASTKD5,GUK1,HINT2,TCOF1,GARRE1,HSPD1 |
| 8.960e-05 | -9.32 | FPR2 (formyl peptide receptor 2) | protein interactions | 2358 | 136 | 59 | 19454 | 5460 |
FUNDC2,MSMO1,RMND1,ARL6IP5,DERL2,MFSD5,CD63,SSMEM1,CAMLG,PEX3,FITM2,FAM241B,CAMP,FXYD6,DOLK,SLC38A9,FAM241A,MZT2B,SYNJ2BP,TMEM208,SLC6A8,HS2ST1,RRAGB,GPAA1,TMEM87A,ATP2B4,SURF4,AGER,YIPF3,SLC29A1,ATP5PB,VKORC1L1,ATP5F1B,REEP4,GPR89A,NIPA2,SCAMP2,VMP1,REEP6,ATP1A3,SLC30A5,LRRC8C,PXMP2,SLC5A6,CERS6,RER1,RTN4,SLC35F2,DERL1,HSDL1,RAB29,TMEM184B,LMBRD2,STOM,SIGMAR1,HACD2,RABL3,SYNGR2,SLC19A2 |
| 8.960e-05 | -9.32 | CAMLG (calcium modulating ligand) | protein interactions | 819 | 136 | 59 | 19454 | 5460 |
RAB5C,SLC25A46,LAMP2,PPIB,LAMP3,AGR2,ESYT1,RHOG,CAMLG,IER3,KCNA2,PTPN1,RAB35,GJA1,HSD17B11,DNAJC1,ARF6,LMAN1,TMPO,STX6,DNAJC25,RAB4A,STIM1,HSPA13,RPN1,TMEM31,CRELD1,TMT1A,CYP2C9,RAB3B,ADIPOQ,KRAS,FKBP8,PDRG1,RAB11A,LMNB1,RNF122,CCDC90B,SEC61B,RMDN3,TXNDC12,F11R,SEC63,PGRMC1,ST7,OTULINL,CDC42,SEC62,SSR1,HSP90B1,LMNA,RAB5A,RAB9A,DERL1,SYVN1,EEF1G,TMUB1,PXMP2,STX7 |
| 8.960e-05 | -9.32 | CDK13 (cyclin dependent kinase 13) | protein interactions | 8621 | 136 | 59 | 19454 | 5460 |
RPA2,CDK1,RPLP0,HEXIM1,H1-5,PPP1CB,CNP,NOP53,RPL4,SKP1,RPA3,HADHA,RNF113A,RC3H2,HSP90AA1,FBXO44,RNASEH1,RPL13A,TUBB,PPP5C,APEX1,ESR2,VIRMA,SRPK2,RPS3,PSPC1,CCNF,FGFBP1,TUBB4B,EZH2,SPSB3,POLR2C,MOB3C,MTA3,TOP3B,RAF1,CDK4,JPH4,TUBA1A,DSTYK,EEF2,CHCHD2,SRSF4,SNIP1,NDUFA4,FBXO11,RPL23A,DDX23,PPM1B,CDK12,TTC9C,HNRNPL,RPS16,CDK9,HSP90AB1,AIP,KRR1,SRSF1,RB1 |
| 8.965e-05 | -9.32 | NOL10 (nucleolar protein 10) | protein interactions | 79954 | 156 | 66 | 19454 | 5460 |
SNRNP40,RPL13A,RPL35,PPP5C,APEX1,RPL19,SRPK2,ESR2,RPS3,EIF4A3,ZNF330,FGFBP1,CCT2,FBXW11,ATG3,DCAF4,RIT1,MYC,RPL7A,USP14,NPM3,DGCR8,SRI,STAU1,RPL4,COIL,AATF,RPA3,SIRT7,NLE1,RPA2,RPLP0,RPL26L1,FGF13,SPPL3,RPS10,SURF6,ZBTB2,CCT7,SRSF1,KRR1,MRTO4,EED,DDX23,MPHOSPH10,CHCHD1,H2AC4,RPS2,IFI16,ATG7,NGDN,KRAS,IMP4,RPL17,SNIP1,RPL31,PPAN,FGF3,RPL3,RPS24,SKA3,H2AJ,RAF1,IMP3,RPSA,TP53 |
| 8.965e-05 | -9.32 | TWF1 (twinfilin actin binding protein 1) | protein interactions | 5756 | 156 | 66 | 19454 | 5460 |
ACTR1B,ABCE1,CSE1L,XPNPEP1,HNRNPF,ZBED1,TNF,PRPS1,CAPZA1,UBE2A,FBXO25,DDX39A,SERPINA3,ACTR1A,ACTR2,BMPR2,CAPZA2,BPIFB1,TFRC,NUPR1,SMARCB1,JCHAIN,CORO1C,PRNP,INA,CDC5L,CDK9,DPP4,HDAC6,BCL7C,YWHAG,COPS5,LYZ,RPA3,NCDN,SQSTM1,NMRAL1,UFL1,UNC45A,ATP6V1G1,EEF1E1,ATG16L1,PPP1CB,DCTN4,RPA2,KCTD12,CTTN,GNG12,CSNK2B,CDC7,TUBB,ACTB,DAPK1,CTSB,TMOD3,USP5,UBA3,GNB1,SH3BGRL,RAB11A,CAP2,MYC,USP14,BTF3,CFL1,ICAM1 |
| 8.982e-05 | -9.32 | H1-1 (H1.1 linker histone, cluster member) | protein interactions | 3024 | 466 | 168 | 19454 | 5460 |
H1-6,MCM6,RPS27A,RPL28,IRAK4,GADD45A,CDK5,SLC39A3,RPS24,PLCB1,EZH2,STIM1,TPPP,GLE1,FGF10,RPS23,MAK16,H1-3,MMAA,WDR37,HNRNPL,RPS10,LYAR,RHOH,RPL8,SRSF1,EED,RPLP1,HP1BP3,RPLP2,MRPL18,ARHGAP5,SKIC8,ZCCHC9,HNRNPD,CDKN1B,RSBN1L,DDX50,RPL6,WWP2,MRPL9,NGDN,NOP53,STAU1,ABCC5,ADGB,SF3B1,EP300,LRRTM3,H1-5,DET1,RPF1,RBBP4,RPL7L1,ACTB,ZNF22,FAU,FAIM,ZNF189,RPL37A,SNRPD1,RPS9,FYTTD1,LMNB1,ZCRB1,FTSJ3,DCAF4,PSMD14,ICAM1,RPS26,RPS5,FAM219A,NSA2,MYC,PMPCA,CDKN2D,NOP16,ZNF668,THAP7,MCM4,PAK1IP1,H3C1,HNRNPK,IMP4,NOC4L,THRAP3,MEPCE,RPS13,RPL17,MRPL52,NKRF,RPL3,DMAP1,RBM34,IMP3,OSGIN2,RPSA,CDK4,DDX39A,MAP1LC3B,ZMYM4,RPS16,DKC1,CDC5L,SURF6,AIFM1,RPL12,KRR1,MCL1,CDK6,MPHOSPH10,H2AC4,NOL12,RPS2,RPL10A,EMX2,MOV10,H2AC14,SPATS2L,ZFAND2B,CD81,E4F1,APOBEC3F,RPS15,RPL4,NHP2,UTP23,AATF,BRIX1,DVL2,HELLS,SIRT7,BANF1,PRKCB,LMNA,CDK1,MRPS34,HEXIM1,RPLP0,RPL26L1,PRKCA,ZNF574,RBMS2,CDK7,CCNA2,PRKCE,SRPK2,DEK,RSL24D1,PELP1,RPS3,PRKRA,FGFBP1,RBMX2,RPS20,MACROH2A1,UBASH3B,BICD2,PDCD4,CDC73,ELAVL2,RPF2,CCNB1,RPL7A,RPS17,H2BC9,RPL26,ZSCAN25 |
| 9.003e-05 | -9.32 | GSK3B (glycogen synthase kinase 3 beta) | protein interactions | 2932 | 831 | 282 | 19454 | 5460 |
GMPS,HMOX2,PPP1CC,AR,NONO,FBXO7,PIM2,LRP6,EPHA2,STK11,MSN,ALB,GANAB,GSK3A,CTNNA1,ENO1,CTTN,TUBA1B,GAB1,STUB1,CEP97,CTTNBP2NL,PRSS37,SYNRG,SIPA1L1,CCND1,SAP30BP,RARS1,MET,PDCL,RPLP0,CDR2,HSP90B1,SNAI2,H2AC7,PICALM,LMNA,H2BC12,SQSTM1,HMCES,PRKCB,GID8,RPA3,INPPL1,DVL2,POLDIP2,BRIX1,PIAS1,FBXW7,PPP1R2,HDAC6,TLE1,NFKB1,SSX2IP,ECD,CRBN,TRAK2,SMAD3,PTPN1,ALDH1A3,CAV1,G6PD,MDM2,EIF2B5,SMAD1,SOX9,GGCT,EEF1A1,ANKRD6,TBK1,APEH,SRP72,ERG28,VTA1,CTNND1,PSEN1,GALE,MCM3,SAMHD1,IRF1,NIBAN2,ILK,HSP90AA1,SP1,LMNB1,YWHAZ,TAFAZZIN,GNG12,GNB1,DYNLL1,SYNE4,LMO4,PPP1CB,NOTCH2,ASRGL1,MYL6,SLC25A3,ARCN1,PMAIP1,HADHA,DCTN3,BIRC2,ATP5IF1,TXNL1,DUSP9,SKP1,IGSF21,PSMC1,NSFL1C,PTN,ACTL6B,UBXN6,PDIA3,DICER1,BCL2L1,PPP3CA,CAMSAP2,HAX1,HNRNPD,VCPIP1,LYZ,RASSF8,TRAF6,UBE2D1,DDX23,RPLP1,EGLN3,CACYBP,MPP1,SNX2,INA,NFE2L1,JUN,GFI1,GFPT1,ACTN4,TXNRD1,FEN1,OTULIN,NLRP2,CDK5R1,RBPJ,BZW2,GDI2,BPIFB1,UBE3A,HNRNPA2B1,ATF3,HSPD1,MAP3K11,AKT2,SLC25A5,SSRP1,NAT9,MCM6,UFM1,ARHGAP21,PRKACB,FAM193B,PTPN11,RPF2,AKT3,AKT1,TNFAIP3,IGF2BP1,BICD2,RC3H2,TLR9,SPOP,CSNK2B,SRP54,MID1IP1,CREB1,BCCIP,EIF4H,WSB1,CAPN1,HECTD1,ACACA,DYRK2,PRKCA,SSR1,RPA2,RPRD1B,ELOF1,UGDH,MARS1,HSPA5,BCL2A1,RPS15,KDM1A,EDC3,GAPDH,HP,COPS5,EDEM1,MAP4,AREL1,RPS2,SNRNP70,SMAD4,AKR1B1,ADD1,MCL1,CD274,TMPO,UBXN2B,TP53,RRM1,TBC1D4,CAPN2,DISC1,NFE2L2,GPD2,TFRC,ABCE1,MAP1B,CAPZA1,GSKIP,CSE1L,HNRNPK,SCML1,H3C1,DYNC1I1,RPL39,BTF3,PSMD1,LDHB,MYC,MDH1,FBXW11,CCT2,KIAA1191,GTF2F2,DKK3,DDIT4,LMBR1L,APEX1,STAT2,TCAP,FBXO42,SUFU,TANK,FKBP14,PAK2,DDX5,SF3B1,HSPA8,EEF1G,CTNNB1,PPFIBP1,XPO1,RPL6,YWHAB,FKBP4,AK2,S100A8,ZHX1,MAGED2,GYS1,SWAP70,CLK4,TNIK,HSP90AB1,CCT7,TCP1,MITF,LYAR,DYNC1I2,AFTPH,EEF2,TRAF2,CARTPT,TUBA1A,TPPP,MYO1B,CDK5,EWSR1,TRIM21,CCT8,PABPC1,XPNPEP1 |
| 9.005e-05 | -9.32 | SLC39A14 (solute carrier family 39 member 14) | protein interactions | 23516 | 108 | 49 | 19454 | 5460 |
PEX3,STYK1,RHOG,LAMP3,CD81,LAMP2,DPP4,RAB5C,FAM20C,LMAN1,DIRAS3,STX6,CAV1,ARF6,RHOH,AGK,GJA1,HSD17B11,RAC2,RAB35,HRAS,RND3,RAB4A,MAP1LC3B,COMTD1,TP53,RIGI,KRAS,RAB3B,LAMTOR1,RHOB,RAB2A,RAB11A,RHOJ,SEC61B,OPTN,RPA2,VAPB,RND2,SEC62,CDC42,BET1,STX7,SLC25A51,ADRB2,SYVN1,RAB5A,RAB9A,RHOU |
| 9.005e-05 | -9.32 | IMP4 (IMP U3 small nucleolar ribonucleoprotein 4) | protein interactions | 92856 | 108 | 49 | 19454 | 5460 |
FTL,AATF,STAU1,NOP53,ZNF692,DGCR8,UFL1,NMRAL1,RPA3,ZNF574,RPLP0,RPL26L1,RPA2,H1-5,APEX1,ESR2,RPL10,RPL13A,PRKRA,FGFBP1,RPL37A,RPS3,H1-1,RIT1,ATG3,RPL26,ZNF668,RPL7A,MYC,RPL17,UTP25,SRSF4,KRAS,S100B,RPL31,ILF2,RBM34,IMP3,SURF6,LYAR,RPS10,LDLR,KRR1,SRSF1,RPL8,MPHOSPH10,CHCHD1,DDRGK1,IFI16 |
| 9.005e-05 | -9.32 | CARS2 (cysteinyl-tRNA synthetase 2, mitochondrial) | protein interactions | 79587 | 108 | 49 | 19454 | 5460 |
TIMM8A,METTL15,MAP1LC3B,GABARAPL1,AURKAIP1,MRPL11,PDHA1,COX8A,SDHC,HSPD1,IMMP2L,FASTKD5,MTRF1,GRSF1,MRPS26,TMEM70,RHOG,TCEAL9,MRPL18,GATD3,MAP1LC3A,SSBP1,SLC25A12,PPIA,RGCC,COCH,GABARAPL2,CAPN1,MTRES1,RPA2,GFM1,PGK1,EXD2,RPA3,PTRHD1,GABARAP,TRA2B,HSCB,TUFM,CFL1,PMPCA,MTG2,AUH,CARS1,SPOP,PTEN,TACO1,PSMB6,PSMD4 |
| 9.064e-05 | -9.31 | RAB geranylgeranylation | REACTOME pathways | R-HSA-8873719 | 64 | 35 | 10285 | 3229 |
RAB31,RAB32,RABGGTB,RAB9A,RAB39B,RAB33A,RAB2A,RAB5A,RAB14,RAB8B,RAB19,RAB22A,RAB27A,RAB3C,RAB11A,RAB29,RAB18,RAB33B,RAB6A,RAB37,RAB13,RAB9B,RAB3B,RAB3D,RAB11B,RAB35,RAB5C,RAB4A,RAB30,RAB3A,RAB23,RAB6B,RAB1B,RAB1A,PTP4A2 |
| 9.080e-05 | -9.31 | PRDM16 (PR/SET domain 16) | protein interactions | 63976 | 188 | 77 | 19454 | 5460 |
CYC1,RPA2,KLF3,H2BC11,ATP5PO,CTBP1,KLF12,PPP1CB,CAPN1,HSPA5,MBD3,PDHB,FXR2,HADHA,XRCC5,RPA3,DNAJB6,SMAD2,RPS26,ATP1A1,TUFM,RIOK2,SAMHD1,CUL3,SMARCA5,TECR,RBBP4,COPE,MACROH2A1,CSNK2B,RTRAF,AP2M1,SNRPD1,ELK3,MTA2,ACTR2,TMEM165,NDUFS3,RPN1,CBX3,RPS7,ACTR1A,EGR2,TOP3B,ATP5PB,SSRP1,RIGI,EIF3E,AP1M1,RPS27A,MCM6,KPNA2,RBBP7,H3C1,MYO1B,ATP5PF,SLC25A11,NDUFA4,MAP1B,WDR11,EIF3D,CSNK2A1,COX5A,HMGA1,BAZ1B,ACOT8,PSMD3,CDC5L,ATP5PD,TOP1,NOP58,HP1BP3,TSG101,DLGAP4,MAGED2,SMAD3,THOC2 |
| 9.092e-05 | -9.31 | RHOQ (ras homolog family member Q) | protein interactions | 23433 | 441 | 160 | 19454 | 5460 |
LAMTOR2,RELL1,DAG1,NOS1AP,TIAM1,ESYT1,SLC2A1,SLITRK5,OSBPL8,EHBP1,ITGA6,CDCA3,SLC39A10,RAP1B,ADD1,FLRT2,FCHO2,VTI1B,CAV1,STX6,SLC38A2,TMPO,GFOD2,SLC29A1,BMPR2,PIK3CA,TFRC,ZDHHC8,EXOC3,CASK,UGCG,VAC14,CIBAR1,DLG1,RAB1A,STX8,SNAP23,SLC16A1,WASL,AKAP12,ADD2,SLC6A8,CTNND1,C9orf72,SLC25A1,PPP1CC,DEPDC1B,ARHGAP21,NTAQ1,ATP1B3,ATP1A1,EPHA2,CTNNA1,NECTIN2,GAB1,VAMP3,MACROH2A1,STX10,TRAF7,GANAB,SNX3,YES1,ROCK1,FERMT2,SH3BP4,ADIPOR1,ARHGAP1,PIP5K1A,SPTBN1,CNP,CDC42,SLC12A2,PICALM,STOM,GOLGA5,TIMM23,SDCBP,JUP,CSNK1G3,LEMD3,GIT2,PARD6A,LRP10,ITM2B,ARHGEF6,RAB9A,ITGA2,PIK3R2,FTSJ1,NF2,YKT6,CDC42EP4,CLDND1,WWP2,PIK3R1,WDR11,CTNNB1,OLR1,PPFIBP1,ARHGAP5,WDR6,NEO1,GJA1,BUD31,SPTAN1,GFOD1,TMEM237,VAMP7,DLG3,MARCKSL1,IFNGR1,RPL29,PPP2R1A,TMEM59,PCDH17,PLD3,STX12,AKT2,SCYL2,GNA11,CDK5,EFNB1,JAK1,ROCK2,SLC20A2,FLOT1,VAMP8,PKP4,PIK3R3,ACO2,RALGAPA2,LRRC8C,SLC30A5,BTF3,YWHAZ,LAMTOR1,ILK,SLC7A11,SLC38A1,CDC42EP3,FAM83B,RRAS2,NDFIP1,LAMTOR3,LRRC8A,CHCHD3,NOTCH2,DAAM1,USP6NL,RRAGA,IL6ST,MORN4,EHD1,ABCB1,PAK2,CDC42EP2,PACSIN3,ABCC5,STX7,ITGAV |
| 9.131e-05 | -9.30 | aerobic electron transport chain | biological process | GO:0019646 | 75 | 38 | 18204 | 5365 |
NDUFA1,NDUFS8,NDUFB10,UQCR11,SDHC,NDUFAB1,NDUFS6,NDUFC2,COX7B2,UQCRQ,SDHB,NDUFA5,NDUFB7,COX4I1,SLC25A51,NDUFA2,COX6C,NDUFB8,COX7A1,SDHAF2,COX7B,UQCRC2,UQCC3,NDUFB4,UQCRH,CYC1,COX4I2,COX6A2,NDUFS2,COX5A,NDUFB5,NDUFB6,NDUFV2,NDUFA4,COX8A,UQCRC1,NDUFS3,COX6B1 |
| 9.131e-05 | -9.30 | ATP biosynthetic process | biological process | GO:0006754 | 75 | 38 | 18204 | 5365 |
NDUFB5,ATP5MC1,NDUFB6,ATP5F1D,NDUFV2,ATP5F1B,ATP5F1E,NUDT2,ATP5PD,NDUFS3,ATP5PB,ATP6V1A,UQCC3,DNAJC30,STOML2,NDUFB4,NDUFS2,ATP5MG,ATP5PO,COX11,ATP5MK,NDUFA12,SDHB,LIPA,NDUFA5,NDUFB7,ATP5MC3,NDUFA2,NDUFB8,NDUFA1,NDUFS8,NDUFB10,ATP5F1A,SDHC,NDUFAB1,NDUFS6,NDUFC2,ATP5PF |
| 9.148e-05 | -9.30 | positive regulation of endothelial cell migration | biological process | GO:0010595 | 133 | 60 | 18204 | 5365 |
MIR135B,HSPB1,MIR143,ATP5F1B,MAP3K3,MIR126,MIR200A,MAP2K3,MIR101-1,CALR,ROCK2,FOXP1,GFUS,MIR23A,PLG,MIR939,PIK3CG,PROX1,EMC10,VEGFC,RHOB,MIR10A,SEMA5A,AKT3,MIR132,AKT1,CD40,ANGPT1,FUT1,FGFR1,FGF16,HMGB1,ATP5F1A,WNT7A,MIR150,NUS1,MIR29A,MIR10B,MIR210,VEGFA,FGF1,TMSB4X,NRP1,NFE2L2,FGFBP1,MIR21,MIR30A,MIR146A,STAT5A,SP1,MIR296,MIR221,FOXC2,MIR342,RHOJ,MIR31,AAMP,PRKCA,GAB1,MET |
| 9.165e-05 | -9.30 | GTF2I (general transcription factor IIi) | protein interactions | 2969 | 354 | 132 | 19454 | 5460 |
PPARG,SOST,PPT1,EIF4B,PIH1D1,PTAR1,PPP1CB,RFXANK,PRDX3,ZNF428,UFL1,STAU1,MCMBP,STX7,SLU7,HIRA,EP300,DDX5,GCC1,CCT2,BRCA1,CYP1A1,FBXW11,MYC,CUL3,PSMA4,BTF3,MATR3,STAT1,RBBP4,TSN,RPL7L1,PGPEP1,LGALS3,MAT2B,JAK2,ESR2,MAD2L2,NFKBIA,NFKBIB,ZMYM2,PHF21A,EZH2,CHMP4C,PDHA1,MTA2,TRMT1L,TOP3B,RAF1,SOX2,TULP3,RBBP7,RPL28,KLRF1,EWSR1,ERP29,TRAF6,CBL,RPL6,DPY30,NDC80,INO80E,HNRNPA1,HNRNPL,SUMO2,TCP1,SNX1,EGLN3,HSP90AB1,SIN3A,GJA1,EED,RPA2,LMNA,HEXIM1,SNRPN,CFTR,HDAC3,GTF2I,KDM1A,LSM8,RPA3,INPPL1,BAP1,SIRT7,PML,TLR9,TXNIP,SMAD2,UBE2H,USP14,TUFM,AR,TRIM54,MAP3K3,ZBTB17,VIRMA,SRC,CCNF,UBE2I,TRIM24,MACROH2A1,CBX3,TFCP2,TAB2,TOPORS,RAD23B,FBP1,TP53,TRIM6,EEF1A1,ZMYM3,HNRNPK,MEPCE,RIGI,TFPT,NAE1,PSME1,RAB27A,HAPSTR1,LIPA,TUBG1,H2AC4,NFKB1,MDM2,PTP4A3,DFFA,RCHY1,CDR2L,COMT,EEF1AKMT3,LHFPL4 |
| 9.216e-05 | -9.29 | regulation of peptidase activity | biological process | GO:0052547 | 306 | 121 | 18204 | 5365 |
VEGFA,NCSTN,PMAIP1,CDKN2D,PSMB9,TIMP1,CAV1,SERPINA3,FURIN,BCL2A1,PRELID1,GAPDH,SERPINB9,SFN,DNAJB6,PPARG,IFI16,RPS27L,ARL6IP5,MIR21,PSME2,HTRA2,SERPINB10,SERPINB6,MCL1,IFT57,CLEC7A,SERPINA1,BAX,SERPINB11,MYC,TIMP3,MIR15A,DAPK1,MMP9,ACVR1C,TNFSF10,CST3,EFNA3,SVBP,EPHA4,KLF4,FASLG,SERPINA5,IFI6,RNF34,FAM162A,PSENEN,TIMP4,SERPINI1,PDCD5,SERPINH1,SRC,HSPD1,BCL10,CRADD,PIH1D1,PSMA3,NLRP2,DAP,BAD,SEMG2,JAK2,MIR29C,BCL2L1,MIR339,MIRLET7B,CSTB,PAK2,FIS1,CLDN3,CAAP1,CSTA,HSPE1,IGBP1,CTSD,CSNK2A1,MIR17,ANP32B,PSME1,NLRP3,FAS,CTSK,SERPINB1,BAK1,GPX1,EGLN3,RPS3,BIRC2,CYFIP2,LAMP3,VSIR,TNF,DDRGK1,DPEP1,APH1A,ROCK2,BOK,MUL1,SMAD3,RAF1,MIR24-1,MIR152,S100A8,NKX3-1,TANK,PYCARD,KHDC1,AGER,SOX2,NLRP1,HMGB1,SYK,MIR205,SIAH2,TNFSF15,SPOCK1,CLDN4,SERPIND1,AIFM1,AKT1 |
| 9.243e-05 | -9.29 | Signaling by the B Cell Receptor (BCR) | REACTOME pathways | R-HSA-983705 | 229 | 99 | 10285 | 3229 |
PSMB11,FGFR1,PSMC5,PSMB10,PSMA4,CD28,PSMB6,FBXW11,PSMA2,PIK3R1,AHCYL1,PSMB1,PSMD3,CREB1,PSMB7,CDKN1B,PSMC4,PSMB5,PSMA3,PTPN11,PSMD14,UBB,CBL,PPP2R1A,SKP1,PSME1,AGO1,PSMD7,FGF17,CD80,ORAI2,NCK1,AKT2,CDKN1A,PRKCB,PIK3R3,NFKBIB,PSMD12,FGF7,GSK3A,BAD,PSMD6,HBEGF,FGF3,PSME2,PSMB9,FGF23,PTEN,PSMA5,NFKB1,MET,PSMB3,PIP5K1A,PPP2R5E,ICOS,PIK3R2,FGF1,PPP2R5A,MDM2,TRPC1,STIM1,KRAS,TNRC6C,FGF22,SYK,UBA52,SRC,PSMD10,PIK3AP1,FGF10,CD79B,NFKBIA,MOV10,PIP4K2C,PPP2CB,KIT,HRAS,GAB1,PIK3CA,PSMA6,AKT3,AKT1,PSMD1,PSMB2,FGF16,BCL10,IER3,PSMC1,CD86,PSMA1,PSMC3,TP53,PSMD4,RPS27A,PSMB4,IKBKB,SHC1,RASGRP3,SEM1 |
| 9.322e-05 | -9.28 | ZCCHC8 (zinc finger CCHC-type containing 8) | protein interactions | 55596 | 139 | 60 | 19454 | 5460 |
ATG16L1,PSMC4,PABPC5,RPA2,SNRPA,RPA3,INPPL1,SIRT7,EXOSC4,C1D,PPP2R2C,KDM1A,ZC3H15,MYC,CUL3,AR,SNRPB,BRCA1,RC3H2,EXOSC1,RBM7,THOC6,RIT1,PSMC5,PHF21A,TRIM24,MATR3,PSMB6,MAD2L1,ESR2,PPP2R1A,SOX2,EXOSC8,EZH2,EXOSC3,POLR2C,CYP2C9,EWSR1,SRSF7,DHX9,PSMA1,HNRNPF,SSRP1,MICB,CSNK2A1,XPO1,YWHAH,DIS3L,SNRNP70,DROSHA,HNRNPD,KPNA1,MPHOSPH6,YWHAB,EIF4E2,COX4I1,HNRNPL,THOC1,TOP1,NCBP2 |
| 9.322e-05 | -9.28 | LHFPL5 (LHFPL tetraspan subfamily member 5) | protein interactions | 222662 | 139 | 60 | 19454 | 5460 |
JAGN1,TEX264,TMX2,EMP3,ENTPD3,TMEM254,SEC22B,TIMMDC1,CTXN3,SEC22A,PLP2,LMNA,CMTM7,ELOVL4,PLP1,VAMP3,TMEM229B,GGT7,RMDN3,SERTM1,GJB2,SCN3B,CREB3,SLC35B4,CYB561,TMEM100,REEP6,TMEM50B,RUSF1,ERG28,GPR37L1,TSPAN7,TMEM60,INSIG2,UBIAD1,TMEM31,TFRC,GNAQ,HAS3,SSMEM1,RPRM,MFSD5,FNDC9,TMEM248,TMEM97,SYNJ2BP,TSPO,SLC41A1,CD81,TMEM107,TM4SF18,SLC35A1,TMEM42,FXYD6,FCGR1A,BTN2A2,CLDN22,AQP2,PDZK1IP1,ZDHHC15 |
| 9.330e-05 | -9.28 | COPS4 (COP9 signalosome subunit 4) | protein interactions | 51138 | 194 | 79 | 19454 | 5460 |
COPS2,WDR6,FBXO32,LRRC14,HSP90AB1,COPS7B,DCUN1D1,PRNP,KCTD10,CSNK2A1,COPS5,ELOC,FEM1B,NT5C2,MOV10,DCAF4L2,TAF7,AP5S1,DCAF11,IKBKB,SKIC8,CRBN,SRSF7,PPP1R12A,APBB3,COPS4,CTNNBL1,NEDD8,HUWE1,KRAS,KPNA2,TOLLIP,ANAPC13,DDX39A,SNAPIN,KBTBD4,TP53,CENPM,RHOBTB1,MOB3C,IRF8,SKA3,PRMT5,SYT2,ZNHIT6,CSTF3,VIRMA,UBA3,DYNLL1,FBXO22,SNRNP40,ATP5F1A,FBXO7,BAG3,CCDC85B,COPS7A,SYCE3,CUL3,CUL2,NCKIPSD,DTL,STK11,COP1,DCAF4,EP300,RPA3,BAP1,FOS,SIRT7,FBXW4,SKP1,HSPA5,DET1,WDR77,FBXO42,TOR1AIP2,UBE2M,RPA2,ZNF326 |
| 9.330e-05 | -9.28 | CLK2 (CDC like kinase 2) | protein interactions | 1196 | 194 | 79 | 19454 | 5460 |
SRSF10,HNRNPL,PRR3,EED,SRSF1,ZNF436,PTPN1,WDR6,YWHAB,RSBN1L,ZNF473,SNRNP70,TRA2A,YWHAH,YWHAG,CSNK2A1,ZCCHC10,RIGI,MEPCE,SRSF12,SRSF4,NUP42,THRAP3,HNRNPF,HUWE1,SRSF8,SRSF7,ZC3H11A,PABPC1,SNIP1,PRM1,RNF8,NFKBIL1,PAIP2B,APOBEC3D,JPH4,UBL5,ZNF263,SRPK2,TNPO3,UBE2I,CSNK2B,AP2M1,TRIM27,CPSF1,GTPBP2,CASC3,RBM7,HSP90AA1,ELAVL2,DCAF4,BRCA1,CPSF2,ATG101,HNRNPC,AKT1,SAP18,FTSJ1,YTHDF1,TRA2B,CLK1,PRPF4,NKAPD1,SNRPA,TEX264,NCOA5,CSNK1A1,LUC7L3,DYRK2,LARP4B,SDCBP,RBMS2,SNRNP27,EHHADH,ZC3H14,CPSF4,DDIT4L,PABPC5,ATG16L1 |
| 9.344e-05 | -9.28 | apoptotic mitochondrial changes | biological process | GO:0008637 | 65 | 34 | 18204 | 5365 |
IFIT2,NAIF1,BCL2L1,MIR29C,VDAC2,BLOC1S2,BCL2A1,TP53,BOK,ATG3,PIM2,BAX,SLC25A4,PMAIP1,GGCT,BAK1,ACAA2,SOD2,BNIP3L,PPM1K,MIR29A,BAD,CLU,PPP2CB,MIR17,AKT1,HSPD1,MCL1,FIS1,SFN,PPIF,IFI6,CCAR2,NPTX1 |
| 9.381e-05 | -9.27 | HSPA6 (heat shock protein family A (Hsp70) member 6) | protein interactions | 3310 | 302 | 115 | 19454 | 5460 |
FGFR1,DYRK2,HEXIM1,CFTR,CDK7,GABRA1,PIK3R2,KDM1A,HSPA5,PML,INPPL1,BAP1,NR1I3,TLR9,RC3H2,NCKIPSD,PSMB2,AKT1,CSK,ATP5F1A,RHOJ,DHRS13,KCTD9,NDN,VIRMA,CYP4F12,TSSK1B,PTEN,ZBTB18,TFCP2,INSIG2,TP53,UBL4A,KBTBD4,MAP2K3,NEDD8,MEPCE,SNIP1,FAF1,MAP1B,SHC1,VASH1,DNAJC7,DNAJB2,GAPDH,HDAC6,COPS5,PLEKHF2,FZR1,CDC5L,TMPO,CDK9,SSBP1,SYNCRIP,RNF7,PPARG,PIH1D1,EIF4B,FUNDC1,PRDX3,KRT222,TMEM106B,HSPA8,PELI3,KIAA1191,ILK,DNAJB6,HSP90AA1,SCFD1,COP1,GRB10,COPS7A,MYC,MLF2,BAG3,DYNLL1,PPP5C,RAN,LMBR1L,BAD,PHF21A,LRRC28,AP2M1,EZH2,RAF1,EEF2,CDK20,COPS4,AHCYL1,PABPC1,HSPD1,DNAJB4,RPAP3,TRIM21,CBL,HNRNPD,VCPIP1,STOML2,GSTM3,CISH,MAP3K14,PPIB,COMMD6,COPS7B,HNRNPL,DHX15,HSP90AB1,NUP35,ELK1,EGLN3,PHB1,DUSP6,FOLR1,WDR6,COPS2 |
| 9.381e-05 | -9.27 | RAB3B (RAB3B, member RAS oncogene family) | protein interactions | 5865 | 302 | 115 | 19454 | 5460 |
VAMP8,SEMA4C,TMEM87A,SCYL2,STX12,STIM1,VAMP2,RAB19,FAF2,MACO1,STBD1,RAB11B,CD1A,VAMP7,OCRL,STX5,CDK5RAP3,DDRGK1,ICAM2,RAB5C,LAMP2,STX7,TACR3,GRPR,SLC15A1,STAU1,UFL1,AKAP1,EXD2,VAPB,RAB6A,TOR1AIP2,PGRMC1,NOTCH2,MTMR6,ATP6AP2,RABIF,APLNR,MB21D2,ATP5F1B,FAM83B,VRTN,FAM91A1,ARF1,SLC38A1,SCFD1,LMNB1,LAMTOR1,HSD17B1,RAB11A,CUL3,VEZT,IL12A,FKBP8,SLC6A8,SNAP23,NSDHL,RAB1A,ACVR1,TFRC,SMAD1,MGARP,UBIAD1,SLC29A1,LBR,MTCH2,PREB,CCDC47,SNAP29,CAV1,SLC38A2,LMAN1,CGAS,KCTD15,DNAJC1,CDCA3,EHBP1,CAMLG,SRPRA,PTPN1,OSBPL8,RAB3A,ESYT1,POR,SMAD4,LAMP3,TMEM199,YKT6,RTN4,ARFIP1,MAVS,MTDH,FLCN,TEX264,LEMD3,PDCL,HEXIM1,SLC12A2,GOLGA5,CFTR,SEC22B,ARHGAP1,RABL3,SEC63,UBB,CHRM4,VAMP3,ATP1A1,NRP1,EPHA2,ARFGAP3,GORASP2,HMOX2,DEPDC1B,RAB2A |
| 9.390e-05 | -9.27 | LDLR (low density lipoprotein receptor) | protein interactions | 3949 | 410 | 150 | 19454 | 5460 |
NSDHL,SLC25A10,SFXN1,GLCE,SNAPC3,ERG28,IMP4,KPNA2,CD1B,OLA1,UST,OSGEPL1,YTHDF2,CDK8,TMEM165,SNAPC2,MRPL33,SOD2,MRPL51,PHETA2,EIF4E2,LDLR,EXT1,LCMT1,GATAD1,FCHO2,PRNP,MIF,POLE3,ASNSD1,MSMO1,CD36,AP5S1,USP3,USP2,CHCHD1,SMG9,SMG8,MAP4,RPL10A,WNT7A,FLCN,TMEM126B,DLAT,PDHB,HDAC3,SGF29,GREM2,HSPA5,MYLIP,SF3A1,TIMMDC1,NFYB,TMEM106A,CCNA2,HSP90B1,HEXIM1,HAUS2,PELP1,CREB1,SMURF1,ROMO1,VIRMA,UBA3,CSK,HSPA14,SLC25A1,PTPN11,ATF4,TYW3,USP14,SPOP,CMA1,DNAJC10,PPTC7,ELAVL2,PNPO,PREPL,MORC2,SLC39A7,TRIM37,MSL2,RAB18,SACM1L,CBLL1,B3GNT2,PI15,MAX,WBP1L,TOP3B,E2F4,SAP30,EZH2,TLNRD1,PDHA1,MATCAP1,SART3,NCR3,POLR2L,EED,YBEY,NRSN1,RPLP2,SNX17,RPLP1,PCSK9,DNAJB9,PDIA3,CLPX,ATG9A,INPP4A,BABAM1,DLK2,EMC6,TIMP3,C1D,RAB5A,HNRNPA0,NDUFS2,SSR3,RER1,POLA2,GINS3,NDUFAF6,MTF1,GINM1,SLC16A10,CYP3A5,FDFT1,PIH1D1,PHF12,PELO,CLVS2,SNRPD1,USP16,CREBBP,ACO2,LDHB,MPC1,NXPH3,CUL3,HMGCS1,MCM8,WDR20,OAZ1,KLK5,CBR3,HTRA2,RIT1,GTPBP2 |
| 9.401e-05 | -9.27 | LSM10 (LSM10, U7 small nuclear RNA associated) | protein interactions | 84967 | 24 | 16 | 19454 | 5460 |
WDR77,MOV10,TOP3B,LSM3,RIT1,SNRPE,MIR20A,ZNF473,LSM6,BMPR2,HAPSTR1,MIR10B,SMN1,SNRPG,KRAS,SNRPD3 |
| 9.401e-05 | -9.27 | GST_NTER | prosite domains | PS50404 | 22 | 15 | 12186 | 3388 |
GSTA4,GDAP1L1,GSTT2B,GSTM3,GSTA2,GSTO2,GSTP1,HPGDS,GSTM4,EEF1G,GSTO1,GSTM2,GSTM5,GSTT1,GSTA1 |
| 9.401e-05 | -9.27 | MSRB3 (methionine sulfoxide reductase B3) | protein interactions | 253827 | 89 | 42 | 19454 | 5460 |
C1QL1,BAP1,PTRHD1,FAM168B,TCOF1,PRDM4,PICK1,FHL3,GUK1,SRI,CDK2AP2,TRIM63,ATG16L1,LNX2,GLRX5,METTL15,GABARAPL2,FTH1,DET1,METTL21A,NUDT19,CHMP4C,UFSP1,KLHL7,EEF1AKMT3,AZIN1,TXN,SNRNP40,LYRM2,TXNDC12,MOV10,MTPN,AK3,ISCA2,GAPDH,AK2,SPOP,SKIC8,TRIM23,DCAF4,COP1,FXN |
| 9.404e-05 | -9.27 | Human Thyroid Stimulating Hormone (TSH) signaling pathway | WikiPathways | WP2032 | 68 | 40 | 5310 | 1910 |
GNAI3,MIR937,MAP2K1,CREB1,MAP2K3,MAP2K6,RB1,FOS,AKT1,CCND3,EGR1,STAT1,MYC,PIK3R1,ADCY2,GNAQ,CDK4,PLCB1,IGF1R,JUN,MYL12B,GNG2,APEX1,GNAO1,HRAS,ADCY3,TSHR,SRC,KCNIP3,RAF1,JAK2,PIK3R2,GNAI2,RAP1A,RAP1B,PIK3CA,CDKN1B,GNB1,MIR197,JAK1 |
| 9.419e-05 | -9.27 | Toll Like Receptor 4 (TLR4) Cascade | REACTOME pathways | R-HSA-166016 | 126 | 60 | 10285 | 3229 |
CREB1,ELK1,TLR6,S100B,DUSP6,FOS,TAB1,AGER,JUN,LY96,DNM2,NFKB1,IRAK4,FBXW11,TANK,SKP1,CD36,PTPN4,NFKBIA,TBK1,TLR1,MAP2K3,MAP2K1,PTPN11,MEF2C,PELI3,UBB,PPP2R1A,PELI1,UBA52,TLR4,MAP2K6,MAPKAPK3,TLR3,NFKBIB,ATF1,TAB2,UBE2N,IRF3,TIRAP,MAPK10,UBE2V1,IRF7,PPP2CB,TICAM1,DHX9,MEF2A,HMGB1,TRAF6,DUSP3,TICAM2,TLR2,IKBKB,UBE2D1,BIRC2,MYD88,CD14,UBE2D3,SARM1,RPS27A |
| 9.432e-05 | -9.27 | MITF (melanocyte inducing transcription factor) | protein interactions | 4286 | 60 | 31 | 19454 | 5460 |
TFEB,VIRMA,UBE2I,RB1,TFE3,STUB1,CLK4,YWHAB,FBXW11,PSMD14,CTNNB1,FBXO7,YWHAG,XPO1,YWHAH,USP13,PAX6,PIAS1,ADRB2,SQSTM1,HINT1,EP300,FOS,PML,OTX2,CDKN1A,EGR2,SOX2,SUMO1,ATG16L1,RRAGA |
| 9.432e-05 | -9.27 | PIM3 (Pim-3 proto-oncogene, serine/threonine kinase) | protein interactions | 415116 | 60 | 31 | 19454 | 5460 |
RPF2,SFN,TPM3,HSP90AA1,HSPB1,H2AZ1,GNG12,BAD,ADD1,CORO1C,TMOD3,YES1,SPTAN1,DKC1,SRC,GNB1,GNAI2,SPTBN1,TOP3B,TPT1,TP53,ACTN4,CD59,LMNA,ARPC3,GNAI3,MYO1B,COIL,CAPZA1,RIGI,FLOT1 |
| 9.432e-05 | -9.27 | RNF13 (ring finger protein 13) | protein interactions | 11342 | 60 | 31 | 19454 | 5460 |
AP3S2,UBE2E3,LGALS8,LMNB1,UBE2D1,DHRS7,TMED5,MYC,LAMP2,VAMP7,MANSC1,STAT5A,VTI1B,SPINT2,AP1G2,CD63,UBE2N,TSPAN3,AP1S2,STX12,SNAPIN,PGRMC1,PIP4P1,UBE2D3,SQSTM1,SEC11A,SPCS2,CCNY,VIPR1,RNF167,HSDL1 |
| 9.440e-05 | -9.27 | Glutathione-S-Trfase_C-like | interpro domains | IPR010987 | 32 | 20 | 18521 | 5414 |
GSTM4,GSTCD,GDAP1L1,CLIC2,GSTM5,MARS1,GSTT1,EEF1E1,CLIC4,GSTT2B,GSTP1,GSTM3,HPGDS,GSTA2,GSTO1,GSTA4,GSTA1,GSTO2,GSTM2,EEF1G |
| 9.442e-05 | -9.27 | pattern recognition receptor signaling pathway | biological process | GO:0002221 | 125 | 57 | 18204 | 5365 |
TMEM126A,MAPKAPK3,TBK1,TIFA,TLR5,TLR8,BECN1,IRAK4,TICAM2,TLR10,TRAF6,MYD88,NLRP3,CD14,TLR2,IFIH1,TLR9,TRAF3IP3,OAS1,CGAS,ATAT1,KCNJ8,PRKCE,LACC1,TIRAP,NMI,IKBKB,MAVS,LSM14A,TICAM1,NLRP6,RIGI,IRF7,TLR7,MAP2K6,TLR1,TLR4,PYCARD,RNF34,TLR6,IRF3,PHB2,OTULIN,CD274,HSPD1,BCL10,MBL2,NLRP1,LY96,PHB1,PIK3AP1,TNFAIP3,FCN2,CLPB,TLR3,TNF,NFKBIA |
| 9.447e-05 | -9.27 | NEK4 (NIMA related kinase 4) | protein interactions | 6787 | 574 | 202 | 19454 | 5460 |
PFKFB2,SYNRG,RPS14,CPSF4,CDK1,GOLGA5,H2AC7,TMEM74,RPS12,RPS20,STUB1,TUBA1B,CTNNA1,ENO1,CTTNBP2NL,RPL22,VIRMA,JUNB,SLC25A4,ATP5F1A,NONO,PPP1CC,TUFM,MAPRE1,STK24,RPL23A,HSD17B10,H2AC25,RPS13,H2AC6,PTGES3,MDC1,TCP11L2,ERLEC1,CTDSP2,EEF1A1,RPL15,H2AJ,CCT5,ILF2,ABHD4,NLRP1,TRAK2,H2AZ1,AIFM1,RPL12,ACTA2,RPL35A,TOP1,LAMP3,MFN1,H2AC14,UPK1A,EIF5A2,FOXD3,ATPAF2,FTL,FOXP2,DUSP26,PRKAB1,ACTL6A,PGRMC1,MYL6,SLC25A3,H2AC1,VPS18,SNRPD1,SNRPD2,RPS9,IFT172,CPSF1,MRPL23,ACTB,TUBB,RBBP4,RPL35,PRPF31,ELMOD2,MCM3,MCM4,RPS5,HSP90AA1,KLHL1,CBR3,YWHAZ,MYO6,OMG,PCNA,BAG2,RPS24,SLC25A5,ZYX,HNRNPA2B1,RPS27A,ACTN4,ERLIN2,FEN1,POLR2C,SF3B5,SNRPE,RPN1,BZW2,RPLP1,HP1BP3,RPL8,PPP2CB,DHX15,CCAR2,RPL7,SPTAN1,HNRNPA1,PSMD3,PRPF19,PDIA3,PRDX1,HNRNPD,SKIC8,PPM1B,RPL27,PML,H2AC13,SEPHS2,TRIM36,HECTD1,ADAMTS20,RPS3,CACNB2,RPGRIP1L,RPS17,IGF2BP1,CALU,CHCHD4,CLPB,RPL3,DHX9,MAP1B,ATP5PF,SLC25A11,CAPZA1,H2AX,ACTR1A,ZMYM4,CHRM3,RPSA,SLC39A10,SYNCRIP,EEF1B2,SSBP1,UGT2A3,RPL32,MYL12A,TMPO,CDC5L,RPS16,DNAJB2,RBM17,RPS2,AKAP8L,MAP4,RPL10A,RPL24,SMCHD1,SF3B1,HNRNPA0,SRSF2,RPL27A,SF3B4,REG1A,ATP6AP2,RPL10,ATP5F1B,MATR3,TTC33,COX10,PSMA4,HNRNPC,SFN,PAPOLA,PIWIL4,H2AZ2,RUVBL2,RPS4X,PSMA1,HNRNPF,PSMA2,RUVBL1,TUBA1A,EEF2,FAM83C,RPS23,TUBB4B,CORO1C,SSR2,SRSF1,HSP90AB1,HNRNPL,SNRPD3,TCP1,YWHAG,XPO1,DDX50,YWHAB |
| 9.452e-05 | -9.27 | SEPHS1 (selenophosphate synthetase 1) | protein interactions | 22929 | 73 | 36 | 19454 | 5460 |
ATG3,WDR12,HSPB1,CRMP1,CUL3,PYCR1,XAF1,SEC13,TUFM,XPO1,HYPK,UMPS,G6PD,CLIC4,CSTF3,MAT2B,FAIM,COPS2,ZNF526,CRKL,SEPHS2,PPIL3,TPD52,SLC35F6,SOX2,ACADS,REXO2,SEPHS1,AHCYL1,IGSF21,ZBTB25,BAP1,RTCB,ERG28,HSPA8,SAT1 |
| 9.452e-05 | -9.27 | FSD1 (fibronectin type III and SPRY domain containing 1) | protein interactions | 79187 | 73 | 36 | 19454 | 5460 |
VTA1,PYGB,FTL,PTRHD1,EHD4,SPECC1L,BIRC2,CDK5,GNG5,TCEA1,PAK2,DISC1,GAMT,SCLT1,STAMBP,TRIM36,EFHD1,ARHGAP1,DDAH1,ETF1,UBLCP1,SRC,EFHD2,CHAC2,FAHD1,TES,PPP1R16A,ARL2BP,CHRAC1,UBE2E3,SERPINB1,UBFD1,NAA50,PTPN11,YWHAH,HMGCS1 |
| 9.452e-05 | -9.27 | RELL1 (RELT like 1) | protein interactions | 768211 | 73 | 36 | 19454 | 5460 |
SNX18,RHOH,RHOJ,ATP5F1B,MGAT1,ARF6,CAV1,DIRAS3,HRAS,RAB35,RAC2,GJA1,RHOB,LAMTOR1,RHOG,RAB5C,LAMP2,RAB2A,KDSR,DNAJC5,LAMP3,CERS2,KRAS,STX7,PDE2A,RHOU,ATP5IF1,RELL2,RND3,OXSR1,BET1,TCAF2,ATP5PB,RABL3,RND2,CDC42 |
| 9.525e-05 | -9.26 | CSNK1E (casein kinase 1 epsilon) | protein interactions | 1454 | 296 | 113 | 19454 | 5460 |
BICD2,DNAJC10,UBE2H,CA2,SEC13,FAM110B,PPP1CC,ARHGAP21,FBXO7,PPP1R10,TNFRSF1B,CTTN,CCNF,FKBPL,PPP2R5E,STOX2,TMEM74,CSNK2B,RPA2,ACACA,SNX22,FAXC,KDELR2,TRIM3,PRPF4,PNO1,DVL2,TEX264,MAVS,TIAM1,ANKRD49,KLHL22,PPIL4,TMA16,FZR1,AKAP17A,RAB39B,SSMEM1,SCG5,ALYREF,WDCP,DCK,FAM199X,NLRP1,CAPZA2,DDX42,DTD1,INSIG2,TP53,ANKRD6,FBP1,SOCS3,ARHGAP12,FKBP8,PRDX4,RIGI,CTNND1,PSME1,EIF1AD,LTBR,SNIP1,YWHAZ,FBXW11,TAFAZZIN,FAM83A,BLOC1S5,FAM107A,CUL3,CUL2,MYC,UBE2S,TACO1,PRMT5,FAM83B,RMDN3,RNF7,USP39,CSNK1A1,MAPKAPK5,RND2,RP2,SNX24,UNC45A,FOXP2,FTL,HSPA8,ATP5IF1,CRY1,PPM1B,YWHAB,CDC23,NDC80,SAV1,DPY30,TMEM208,ZCCHC10,TRA2A,YWHAH,XPO1,DBNDD1,YWHAG,LYAR,NOB1,STK3,MTA2,CSNK1E,TULP3,KIF2A,DHX16,AHCYL1,PDIA6,TRIM11,LDLRAD4 |
| 9.547e-05 | -9.26 | GPI (glucose-6-phosphate isomerase) | protein interactions | 2821 | 200 | 81 | 19454 | 5460 |
CUL3,ACO2,MYC,BAG3,PSMD1,PPTC7,BRCA1,GLOD4,SORD,UBE2H,ATP1A1,ENO1,PTPRZ1,NDN,TAMM41,VIRMA,SNRPB2,CFTR,NEK7,MRPL12,NDUFAB1,IGFBP3,IDH2,RPA2,SPRYD4,FKBP1A,AKR1A1,ANXA7,ARCN1,MET,UBE2M,RPA3,SOD1,PEBP1,BAP1,PRDX6,HSPA8,TMEM256,EMC1,EIF5B,LYPLA2,PMM2,DPP4,PDIA3,ZNF207,HDAC6,PPM1D,CSNK2A1,AGR2,BRD3,NQO1,MT1X,TST,UBE2N,SDHB,LDLR,TES,ESD,RAF1,TOP3B,CMPK1,FEN1,PGM1,SOX2,HADH,ISG15,CHMP4C,NGB,EZH2,PLS3,TFCP2,MOB3C,PPME1,EMC2,PCNA,HAPSTR1,PIK3CG,KRAS,EPHA4,HUWE1,SOCS2 |
| 9.586e-05 | -9.25 | IL2 signaling events mediated by STAT5 | Pathway Interaction DB | il2_stat5pathway | 30 | 21 | 2226 | 782 |
PIK3CA,CDK6,STAT5A,SP1,SHC1,CCND3,ELF1,CCNA2,JAK1,PIK3R1,MYC,PTPN11,FASLG,LTA,IL2,IL2RB,IL2RA,IL4,BCL2L1,FOXP3,IL2RG |
| 9.591e-05 | -9.25 | DUSP11 (dual specificity phosphatase 11) | protein interactions | 8446 | 81 | 39 | 19454 | 5460 |
MRPL13,PRR3,RPL32,FBLN5,SYNCRIP,SURF6,MRPL24,THOC1,MRPL50,MRPS21,HNRNPA1,CIAO1,MRPS35,HNRNPC,RPS2,MRPS26,MRPS25,FBXW11,MRPL18,MRPS16,MRPS11,SRSF7,FGF3,AHCYL1,PTGES3,MRPS7,MRPL22,KCTD17,RPS15,RPL15,RBMS2,DDX39A,APOBEC3D,NOTCH2,RAF1,PABPC5,PRKCA,APOBEC3C,KCTD12 |
| 9.591e-05 | -9.25 | DNMT3L (DNA methyltransferase 3 like) | protein interactions | 29947 | 81 | 39 | 19454 | 5460 |
GTF2H2,SMAD3,CREB1,NR1I2,ESR2,JUNB,RSL24D1,NR1H2,CREBL2,LDB1,ATF1,NFKB1,ATF4,ID1,LHX2,NR2E1,SMAD4,MECP2,FOSL2,DR1,DDIT3,NR1I3,FOS,ATF3,MEF2A,EGR1,PAX6,NFIL3,GTF2I,HAND2,JUN,EGR2,SMAD1,KLF12,MAX,DMTF1,E2F4,TP53,E2F6 |
| 9.610e-05 | -9.25 | P2RY2 (purinergic receptor P2Y2) | protein interactions | 5029 | 111 | 50 | 19454 | 5460 |
YIPF5,SLC19A2,TOMM22,RABL3,CAV2,FAM8A1,GOLGA5,GHITM,DERL1,SYVN1,ATP5IF1,TMEM160,DAD1,ITGAV,CMTM6,RER1,GOSR1,RNF5,SLC30A5,TM9SF4,NLRP3,ENDOD1,ATP1A3,INTS12,SLC30A7,SCAMP2,APEX1,SRC,TNPO3,VKORC1L1,CD47,LBR,SLC29A1,IPO8,ITGB5,KDELR1,SURF4,RINT1,ATP2B4,GPAA1,TMEM87A,SACM1L,HS2ST1,PGAP4,MOV10,SYNJ2BP,STX5,SLC39A10,RMND1,DERL2 |
| 9.643e-05 | -9.25 | MPRIP (myosin phosphatase Rho interacting protein) | protein interactions | 23164 | 203 | 82 | 19454 | 5460 |
PTP4A3,SNRNP70,UQCR11,ANKRD50,YWHAB,ZNF24,IFI16,DPP4,CTNNB1,HDAC6,YWHAH,YWHAG,ERLEC1,TNF,PSMA1,DPM2,FBXO25,PPP1R12A,NTRK2,TMEM147,CHMP4C,CAPZA2,TFCP2,APEH,NUPR1,FURIN,PSMC3,RND3,JPH4,RAF1,TOP3B,ISG15,RPGRIP1L,ACTB,ESR2,VIRMA,DYRK1A,SH3BGRL,UBE2V2,CTTN,CCNF,PTEN,RHOB,YWHAZ,ARMC7,EPHA2,NRP1,SFN,MYC,DNAJC5,PPP1CC,RACGAP1,USP14,AGAP2,PDE4B,BTF3,STAU1,FBXW7,NF2,SGF29,LSM8,PACSIN3,HSPA5,FOS,RPA3,DDX39B,RHOU,SQSTM1,MIA2,AP1AR,RPA2,VAPB,CSNK1A1,TMOD1,PGRMC1,CAPN1,TPT1,WDR77,WDR83,ATG16L1,CFTR,PPP1CB |
| 9.654e-05 | -9.25 | regulation of mitotic cell cycle | biological process | GO:0007346 | 530 | 196 | 18204 | 5365 |
MIR195,TPRA1,EZH2,MIR29A,MIR137,FBXO7,MIR638,RAD21,MNAT1,RRM1,SMARCB1,NDC80,CHMP4C,NBN,PSME2,CCNB1,MIR193A,CUL3,CDKN1B,RNF20,KLHL22,BTG2,AFAP1L2,GPNMB,ANAPC16,TMEM14B,MIR15A,NEK7,VPS4A,DTL,MDM2,BRINP1,NLE1,CDC26,SDCBP,PAFAH1B1,MIR133B,ACTL6B,BIRC5,TP53,CDK2AP2,CDC23,LCMT1,ERCC3,PTPN11,KLF4,CKS1B,PHB2,JADE1,CDK6,FGFR1,TRIM35,BRINP2,MIR16-1,CACNB4,CRADD,ZNF655,TERT,DYNLT3,DCUN1D3,RB1,IK,CCL2,NHERF1,CDKN1A,CDK9,NUP62,PML,AIF1,CDK4,RNF40,BCL7C,CCNH,MIR214,NEK2,PRKCA,ACVR1,MIR222,NAE1,PSME1,TMOD3,FBXO31,NEK9,CDKN2C,DUSP1,RPA2,RAB11A,TNF,CRLF3,ACTB,IL10,POLDIP2,NKX3-1,PKIA,RINT1,MIR495,BCL7B,TOPBP1,ANAPC13,NUF2,BCL6,BABAM1,CD28,PIM2,RPRM,CDKN2D,MAD2L1BP,ANAPC15,RBBP8,SIN3A,MAD2L2,MEPCE,WNT10B,ANAPC2,LSM10,CKS2,ECD,MIR519D,RPS27L,PPP1R10,MIR21,CDC73,ZMPSTE24,HDAC3,PLCB1,THAP1,MDC1,SMARCD3,MIR208A,RGCC,BRCA1,MAEA,ANAPC4,IER3,TOM1L1,EIF4E,USP2,CDC42,FZR1,BTG1,CDC20,ZNF207,UBE2E2,CDC16,BTN2A2,MTA3,DAPK3,SMARCE1,CTDSP2,ACTL6A,CDK1,AURKAIP1,PRMT2,CDK5RAP3,BTG3,MIR29C,PTEN,MAD2L1,NABP1,E4F1,ANAPC11,CAV2,MIR221,CTDSP1,PSMG2,CCND1,DLG1,BRINP3,CDK7,CYP1A1,BUB3,AATF,RIOK2,FZD3,SPC24,FGF10,CTNNB1,CCND3,ADAMTS1,TTL,IGF1,OVOL1,DUSP3,IL1A,PRMT5,VPS4B,DRD3,RPL26,TOM1L2,GMNN,CDC7,FAM107A,IL1B,RPA3,AKT1,NOP53 |
| 9.659e-05 | -9.25 | BCLAF1 (BCL2 associated transcription factor 1) | protein interactions | 9774 | 290 | 111 | 19454 | 5460 |
WWP1,RPA2,LEMD3,EPHX1,DYRK2,SF3A1,CDK7,FBXW7,HMGB1,RPS15,AATF,RPA3,RPL27,RNF113A,RTN4,CLK1,RC3H2,UBE2H,STK11,CCNB1,PPP1CC,PRKCE,YES1,NDN,SRPK2,VIRMA,SMURF1,CCNF,RPS3,GSK3A,CSNK2B,IK,NUPR1,MTCH2,FBP1,CD2BP2,THRAP3,CAMKV,TCOF1,SNIP1,ZC3H11A,CD9,SNRNP70,CDK12,MOV10,H2AC14,CSNK2A1,THOC1,TOP1,CAND1,ZBTB2,ALYREF,ARL4D,LARP4B,ALKBH3,ELK4,STAU1,UFL1,ASB3,NKAPD1,THOC3,DDX39B,SNRPA,RAB5A,HSPA8,SF3B1,LMNB1,CHTOP,THOC6,CDKL2,CUL3,HNRNPC,MYC,APOBEC3B,HNF1B,BAG3,SNRPB,RIOK2,BTF3,RNF40,SNRNP40,MATR3,ERH,CMTR1,RPS9,HDAC11,GLE1,DCAF8L2,SART3,SUPT5H,RAF1,PAIP2B,DNAJC25,SOX2,ISG15,CHCHD2,KRAS,POLDIP3,SSRP1,ARGLU1,RPL31,TRIP4,SRSF7,DDX23,BCL2L1,AHSA1,MED4,DDRGK1,XPO1,YWHAG,THOC2 |
| 9.661e-05 | -9.24 | NCOA4 (nuclear receptor coactivator 4) | protein interactions | 8031 | 45 | 25 | 19454 | 5460 |
XPO1,BTF3,AR,AKT1,RNF14,CUL3,PSMD14,GTF2B,OPTN,EGLN3,SPPL3,TAX1BP1,MAP1LC3B,FTH1,VDR,RAF1,PPARG,TRIM5,RNF10,SQSTM1,GRIA2,PSMC1,FTL,TFG,HUWE1 |
| 9.661e-05 | -9.24 | PILRB (paired immunoglobin like type 2 receptor beta) | protein interactions | 29990 | 45 | 25 | 19454 | 5460 |
ATP5F1B,ASIC1,ATP6AP2,KDSR,EI24,PTPN11,ATP5MG,ATP5F1A,FAM241A,FAM241B,NME2,ATP5MC1,BRCA1,TMEM70,REEP6,TSPAN15,TAPBP,SLC35F2,RTN4,CERS2,RIGI,ATP5PB,SLC19A2,ATP5PO,GALNT1 |
| 9.718e-05 | -9.24 | ATP4A (ATPase H+/K+ transporting subunit alpha) | protein interactions | 495 | 100 | 46 | 19454 | 5460 |
KBTBD4,FAF2,LGR4,VAMP2,STX12,GNAQ,RAB1A,SYPL1,ATP1A2,VAMP8,CTNND1,RAB5C,GNG2,ATP1B1,AGR2,HAX1,PTPN1,ARMC1,ATP6V1A,ARL6IP5,RAB11B,CAV1,TPRA1,SYNGR2,SEC22B,VAMP1,SLC12A2,HEXIM1,EPHX1,FAM3C,MRC1,ANXA7,CLK1,UFL1,GPM6A,STX7,VAMP5,RAB11A,ATP1A3,NAPA,ATP1A1,RRP7A,VAMP3,SCAMP2,GANAB,GNAI2 |
| 9.718e-05 | -9.24 | PRIM1 (DNA primase subunit 1) | protein interactions | 5557 | 100 | 46 | 19454 | 5460 |
MDFI,MOV10,UBXN6,ATG7,YWHAG,BTF3L4,EEF1AKMT3,TOP1,EGLN3,POLE3,HSP90AB1,TP53,CDK8,PNMA2,PSMC3,S100B,PCNA,RPAP3,KRAS,H3C1,PSMA2,CCAR1,MDC1,CIAO1,BTF3,STN1,RIT1,TNFRSF1B,POLR3H,MAD2L1,PSMC4,TANK,PSMB3,RFXANK,CDK7,LMNA,RPA2,DUSP9,PRIM2,RPA3,XRCC5,POLD2,SLC31A1,STAU1,PSMC1,POLA2 |
| 9.718e-05 | -9.24 | UMPS (uridine monophosphate synthetase) | protein interactions | 7372 | 100 | 46 | 19454 | 5460 |
ISOC1,RPA2,ADSS2,SEPHS2,HSCB,RPA3,EP300,EXOSC4,RIT1,UBE2H,CALU,VMP1,CUL3,AKT1,RPS29,DLST,CCNF,CDC42EP3,LMBR1L,GNPDA1,GNPDA2,PIK3CA,TP53,GBE1,RAF1,PLA2G12A,TGFBR2,EPHA4,SEPHS1,PSEN1,RB1CC1,PGAM1,FAM174A,MOV10,HMBS,GLO1,DDRGK1,PRNP,SUMO2,AASDHPPT,CDC5L,EGLN3,PHB1,HRAS,RB1,SNX17 |
| 9.719e-05 | -9.24 | regulation of monoatomic ion transmembrane transporter activity | biological process | GO:0032412 | 214 | 89 | 18204 | 5365 |
CACNB4,PRKCE,CHRM3,KCNIP2,MIR448,SUMO1,FGF13,SRI,CRHR1,MIR200C,VAMP2,FKBP1A,KCNS1,CCL2,SPHK2,JPH4,TMSB4X,ACTN4,PCSK9,SLMAP,CCR2,ATP1B1,ATP1A2,CAPN1,PPIF,DLG1,CFTR,PLN,SCN2B,NLGN2,CRHBP,TCAF2,VMP1,CHP1,MIR24-1,CACNB3,ABCB1,SCN3B,MIR192,CAB39,TESC,MIR208B,HECW1,DRD3,ADRB2,MIR30D,RANGRF,GSTM2,FKBP1B,NDUFA4,GPR35,FXYD6,CAV3,PRRT1,COX17,KCNAB1,CLIC2,EPO,CAV1,EDNRA,SELENON,STIM1,MIR212,CACNG3,MIR153-1,TLR9,MIR208A,NOS1AP,GSTO1,ATP1B3,HPCA,SCN1B,AHCYL1,MIR1-1,DAPK1,MMP9,CACNB2,WWP2,NLGN1,IFNG,NETO1,OXSR1,PHB2,HOMER1,OPRM1,FGF12,DLG4,YWHAH,STAC3 |
| 9.729e-05 | -9.24 | ACTG1 (actin gamma 1) | protein interactions | 71 | 429 | 156 | 19454 | 5460 |
EED,CORO1C,FEZ1,TNIK,CCT7,HSP90AB1,WDR44,FHIP1B,DYNC1I2,TCP1,SPTAN1,DDRGK1,CTNNB1,BCL7C,WWP2,YWHAB,COTL1,POU5F1,ACTR1B,RUVBL2,CCT8,BCL7B,TFG,RUVBL1,KRAS,LGR4,ISG15,FAF2,TRAF2,B3GNT2,ERRFI1,TOP3B,SMARCB1,EZH2,MCPH1,RAN,RNF208,NCKAP1,USP5,ESR2,PPP5C,ACTB,DYNLL1,ATP5F1B,BTF3,SMARCE1,SFN,MYC,ACO2,SP1,HSP90AA1,PSMD14,YWHAZ,BRCA1,CCT2,DCTN3,PSMA3,GPHN,HSPA8,DDX39B,FBXO30,WASF3,PYGB,ADRB2,UCHL3,UFL1,CYFIP2,ELK4,PPP1CB,TANK,EHHADH,PAFAH1B1,ACTL6A,ARCN1,CSNK1A1,KLC2,PRSS23,LDLR,ADD1,DSTN,H2AZ1,HRAS,G6PD,CDK9,PLG,HDAC6,SPATS2L,TOPBP1,TMOD2,SHC1,TMEM11,MRFAP1,FAF1,DUSP19,RIGI,CAPZA1,FBXO25,MEPCE,CTNND1,WASL,TOLLIP,ARHGAP12,EEF1A1,MAP1LC3B,ACTR1A,CCT5,TP53,INSIG2,UBL4A,NUPR1,ARPC3,DISC1,CAPZA2,DMAP1,CBX3,UBASH3B,TMSB4X,CTTN,OPTN,CCNF,SRPK2,SH3BGRL,USP14,PPP1CC,CFL1,CFL2,NTAQ1,MORF4L1,CAP2,GZMK,NCKIPSD,CCDC22,TLR9,RC3H2,PIP4K2C,SPOP,SQSTM1,ARPC2,RNF113A,MNS1,HSPB2,PSEN2,PML,SS18,HSPA5,SGF29,CDK7,CFTR,SPTBN1,TMOD1,PRKCA,GIT2,HEXIM1,FGFR1,STOM,DCTN4 |
| 9.845e-05 | -9.23 | choroid_plexus | COSMIC cancer mutations | choroid_plexus | 10 | 9 | 16828 | 4835 |
TP53,CTNNB1,KIT,IDH2,IDH1,NF2,PTPN11,TERT,SMARCB1 |
| 9.882e-05 | -9.22 | myosin V binding | molecular function | GO:0031489 | 17 | 13 | 18094 | 5411 |
RAB11B,NPC1L1,RAB6A,RAB39B,RAB6B,RAB14,RAB27A,GRIA1,RAB3B,RAB3D,RAB11A,RAB3C,RAB3A |
| 9.884e-05 | -9.22 | RPAP3 (RNA polymerase II associated protein 3) | protein interactions | 79657 | 212 | 85 | 19454 | 5460 |
RPRD1B,RPA2,SAMM50,TTI2,PARD6A,PIH1D1,POLR1D,PPP1CB,CCNA2,KDM1A,STAU1,POLR1H,HELLS,RPA3,PML,HSPA8,EP300,FBXW11,BRCA1,BICD2,PIP4K2C,STK11,HSP90AA1,PFDN2,HTRA2,PFDN6,RIT1,POLR1B,MYC,TM9SF4,CUL3,SFN,RFC5,ST13,MCM3,PPP1CC,DAPK1,ADRM1,PSMB6,POLR2B,CCNF,NFKBIA,POLR3B,POLR3H,PHF21A,POLR2F,ANAPC2,POLR2D,POLR2G,STX12,POLR2C,KBTBD4,CCT5,PPP2R1A,RPAP2,ACTR1A,KRAS,HNRNPF,DNAAF10,RUVBL1,PDRG1,FBXO25,IMMP2L,PTGES3,PRDX4,PRPS1,FKBP8,RPAP3,RUVBL2,ASB7,YWHAB,HSPB1,ZNF24,WWP2,XPO1,YWHAG,RPS10,NOP58,POLR2I,EGLN3,CACYBP,LMAN1,HSP90AB1,RPRD1A,POLR2L |
| 9.892e-05 | -9.22 | ficolin-1-rich granule lumen | cellular component | GO:1904813 | 124 | 56 | 19108 | 5553 |
MIF,PSMB7,TNFAIP6,JUP,CAPN1,PSMD7,COMMD3,PLEKHO2,PDAP1,PSMD14,EEF1A1,HMGB1,PSMA5,CTSD,PNP,HBB,SRP14,PAFAH1B2,FTH1,PSMB1,CALML5,CTSB,ACTR2,CAB39,APEH,PRDX4,PGAM1,CAND1,ATG7,GSTP1,PSMD6,HUWE1,MMP9,CSTB,PSMC3,HSP90AB1,IDH1,HSP90AA1,ACTR1B,COMMD9,EEF2,CST3,PGM1,NME2,YPEL5,COTL1,SERPINA1,CSNK2B,ILF2,HSPA8,PSMD3,PSMA2,CCT8,PSMD12,PPIA,FGL2 |
| 9.913e-05 | -9.22 | ZNF189 (zinc finger protein 189) | protein interactions | 7743 | 50 | 27 | 19454 | 5460 |
NOTCH2,MACROH2A2,APOBEC3C,RPL23A,RPL3,BMPR1A,RPL28,RPL17,KRAS,DGCR8,NOP53,RPL4,RPL26,STK4,RPL7A,STK11,NOL12,H1-1,SMAD4,FGFBP1,KRR1,CTNNA1,SRC,SURF6,APEX1,STK3,HNRNPL |
| 9.913e-05 | -9.22 | BTBD9 (BTB domain containing 9) | protein interactions | 114781 | 50 | 27 | 19454 | 5460 |
RND3,CTXN1,UBE2M,RAD23B,MSRB3,CSNK1A1L,TIRAP,ATP6V1G1,NEDD8,TRIM63,HSPB2,ZC3H7A,PDIA6,SKA1,VPS26B,TNFAIP1,FAF1,LSM3,EXOSC1,SMAD2,CBR3,KIAA1143,COPS5,CUL3,VIRMA,DCUN1D1,HNRNPL |
| 9.913e-05 | -9.22 | GHR (growth hormone receptor) | protein interactions | 2690 | 50 | 27 | 19454 | 5460 |
IGF1R,JAK1,SKP1,SOCS2,PIK3R2,NEDD8,SOCS3,DDX39A,GH1,GHR,RNF7,SGTA,STUB1,FBXO31,PTPN1,SRPK2,JAK2,STAT5A,ELOC,CISH,PTPN11,GRB10,PIK3R1,AP2A1,SHC1,FBXW11,NCK1 |
| 9.913e-05 | -9.22 | TBC1D17 (TBC1 domain family member 17) | protein interactions | 79735 | 50 | 27 | 19454 | 5460 |
TOP3B,CCT5,MTCH2,GABARAPL1,MAP1LC3B,LGR4,UBAC2,ZRANB2,STX12,SLC25A5,CXCR4,RAB1A,RAB5A,CDKN2D,CUL2,RAB5C,XPO1,FIS1,OPTN,MAP1LC3A,TES,SPPL3,RPS16,OSBP,TAX1BP1,SLC25A31,APEX1 |
| 9.948e-05 | -9.22 | XPO5 (exportin 5) | protein interactions | 57510 | 215 | 86 | 19454 | 5460 |
STBD1,TOP3B,SOX2,NUP153,AQP3,RHOBTB1,SMARCB1,RPL31,PDIA6,KRAS,PFDN5,NDC80,KRBOX4,DDRGK1,NCR3LG1,PPP3CA,MRTO4,SUMO2,ATXN10,SERINC3,RAB33A,SHMT1,DIO3,TSPAN15,LCA5,CD40,EP300,NUP50,TTC1,EMC1,NPTN,CUL3,RAB11A,GPR17,MYC,RIT1,RAN,LMBR1L,GPR173,EDNRA,TNFRSF9,ESR2,MAT2B,APLNR,COMTD1,MAP1LC3B,EEF1A1,TFRC,PPME1,PPP1R12A,IGF1R,HAPSTR1,MEPCE,ANKMY2,DPP4,MOV10,GTF2E1,SMAD4,HRAS,ADD1,CDC5L,ILVBL,PTP4A3,CCND1,HCST,STOM,RPA2,P3H1,SIRT7,RPA3,UGDH,BAP1,RNF113A,VIPR1,HSPA5,GSTK1,RALB,AR,CHORDC1,UBE2H,SNX5,ZNF330,CCNF,AMIGO1,CTSB,VIRMA |
| 1.000e-04 | -9.21 | negative regulation of synaptic transmission | biological process | GO:0050805 | 41 | 24 | 18204 | 5365 |
ACHE,ATAD1,SLC6A4,ADIPOQ,STXBP1,ARF1,DRD1,ABHD6,PCDH17,NPY5R,PRRT1,ADNP,CD38,GABBR1,SLC6A1,GRIA1,ADORA1,TNR,HTR2A,IL1B,GNAI2,GRM2,PICK1,DRD3 |
| 1.005e-04 | -9.21 | DDA1 (DET1 and DDB1 associated 1) | protein interactions | 79016 | 367 | 136 | 19454 | 5460 |
SRP14,ETV6,NT5DC1,TRAPPC3,CAND1,MIF,ESD,SURF6,ZNF24,COPS5,TUBG1,CRBN,MPHOSPH10,AKAP8L,NOSIP,PQBP1,HAPSTR1,SLC16A1,CDC40,BACH1,MNAT1,STRBP,CCT5,CD2BP2,SOCS3,RPL15,CBX3,RP9,CAPZA2,PPP4C,TAF2,RTRAF,PHAX,INTS12,TXN,RPL13A,CSTF3,TFEB,SUGP1,RPL7A,GMPS,RACGAP1,DCAF16,TADA3,UBE2E3,TEX19,DTL,CDC73,BAP1,RDH10,IDH3A,PGK1,HNRNPH2,TCEA1,DGCR8,PIAS1,GTF3C4,DYRK2,HNRNPH3,ACACA,PRCC,RBM5,EED,COPS2,COPS7B,PRPF18,EGLN3,LRWD1,HMGA1,POGK,UBE2E2,EIF3D,NGDN,DCAF5,FOSL2,SKIC8,DROSHA,FKBP4,DCAF11,RPL23,MRPS11,PDIA6,KRAS,RBBP7,ZNF592,ETFA,IMMP2L,SSRP1,COPS4,HNRNPDL,UTP25,ANP32A,SUPT5H,KHDC4,DHX38,JUN,CRTC2,RPS7,ELF1,RIMOC1,RPL18,TRMT6,PSMD4,ZCCHC7,DYNLL1,RBBP4,RPL10,CREBBP,COPS7A,HNRNPC,CFAP20,CUL3,SAMHD1,MCM3,CPSF2,SNX10,DCAF4,COP1,FOS,EMG1,HADHA,DR1,EP300,SRM,EYA3,RADX,LNX2,RPL27A,LAP3,ASB8,TOR1AIP2,AGTRAP,RFXANK,DET1,ADNP,FEM1A |
| 1.005e-04 | -9.21 | LNX1 (ligand of numb-protein X 1) | protein interactions | 84708 | 565 | 199 | 19454 | 5460 |
YWHAZ,ZCRB1,BLVRA,EXOC8,HSP90AA1,PKP4,TMED4,TSN,LRRC3B,JAK2,PNMA1,AP2M1,ABCB1,AGTRAP,ALKBH3,LNX2,FOXP2,PSMC1,COIL,ATPAF2,ZFP64,CLDN1,SAT1,BIRC2,RABAC1,TRAF6,LHX2,NAB2,INO80E,NDC80,TRIM8,HSBP1,ZNF593,EGLN3,PPIA,MYEF2,TSG101,PPID,NME1,PNMA5,SNCB,CA8,ZNF263,GTF2E2,PPP2R1A,ACTN4,KCTD17,FLOT1,AP1M1,MRFAP1L1,FHL3,REEP6,AP2A1,DHPS,LRRC73,GMNN,SCML2,EIF4A3,TRIM27,HEXIM2,PRKRA,LSM2,PAK5,DCTD,SEC22B,SMC4,RPL4,SGF29,CDC42EP4,LDOC1,ORMDL1,PPIH,CLK1,KXD1,SUV39H1,GOLPH3L,MAPRE2,ZBTB2,CAMK2N2,MDM2,CITED1,UBP1,JOSD1,ZBTB26,FBP1,EXOSC8,THAP1,PQBP1,CPNE2,CIRBP,CDKN2D,PBLD,TMED5,TBC1D1,CCDC85B,DRAP1,THAP7,TAX1BP1,LDB2,RABIF,SCNM1,TACO1,VMAC,PRMT5,CTBP1,PRR13,PAFAH1B1,DUSP14,NUP62,BORCS6,TBCEL,ISCU,SNRPA,DDIT3,TIFA,DRG1,ZCCHC10,RIOX2,PFDN5,C1QTNF1,HMG20A,CIB3,RAB33A,SRSF1,HOMER3,PSME2,CLK4,STX5,PPFIA3,METTL21A,DCUN1D5,KLHL12,PTS,NUP37,SPG21,TRAF2,SSNA1,ZBED1,HNRNPF,PAK6,DCTPP1,LEPROTL1,S100B,FBXO11,TRIM21,RUVBL2,TRIM23,BICD2,EXOSC1,PTPN11,CEP85,TNFAIP3,PCBD1,CEP70,EIF4H,DAPK1,TRIM54,KCTD9,SRC,TRAF1,PAFAH1B3,CDIPT,ZNF655,WWP1,TRIM68,PRKCA,TFIP11,SCLT1,NDUFAB1,MARS1,TRIM10,TRIM3,TNFAIP1,DERL1,EXOSC4,NXT2,KPNA1,ZNF24,CMSS1,ORMDL3,ELOC,EDC3,PNMA3,RPS27L,TMED9,LCP2,EEF2KMT,GUCD1,GRAP2,SAPCD1,SP4,TP53,ZNF581,RBCK1,MSANTD4,SCML1,RPIA,EIF1AD,THG1L |
| 1.006e-04 | -9.20 | RAE1 (ribonucleic acid export 1) | protein interactions | 8480 | 221 | 88 | 19454 | 5460 |
ELOVL1,FKBP1A,AGGF1,PSMB7,STXBP1,NUP62,POLA2,OXCT1,NUP50,DDX39B,PRKD3,YWHAZ,FBXW11,UFD1,SFN,CUL3,ESR2,TAGLN2,DYNLL1,SMU1,POLR3B,LMBR1L,RAN,EFHD2,SMARCB1,GLE1,CHMP4C,NUP153,CCS,SOX2,RAF1,RANBP1,KRAS,NUP42,MAGED4B,LSM14A,PABPC1,MED4,ARMC8,XPO1,YWHAH,DDRGK1,CTNNB1,IFI16,EGLN3,NUP35,STK3,TMEM237,AASDHPPT,WDR82,LMNA,HSP90B1,FAXC,ATG16L1,SF3A1,DGCR8,FBXW7,DERL1,RNF113A,BAP1,SOD1,PRIM2,XPOT,PTTG1,MAPRE1,UBE2H,PPP1CC,BUB3,TXN,GSK3A,POLR3H,CCNF,NUPR1,KBTBD4,TP53,MPST,PSMA5,NUP107,HAPSTR1,HINT1,MAP1B,FAF1,MAP4,USP15,UBXN10,ESD,MIOS,SPPL3 |
| 1.011e-04 | -9.20 | Hedgehog 'on' state | REACTOME pathways | R-HSA-5632684 | 86 | 44 | 10285 | 3229 |
SMURF1,SUFU,GAS8,SPOP,PSMD1,PSMB2,CSNK1A1,PSMA6,CDC73,CUL3,PSMC1,PSMD12,PSMC3,PSMA1,RPS27A,EFCAB7,PSMD4,PSME2,PSMB4,PSMD6,SEM1,PSMB9,PSMA4,PSMA5,PSMB10,PSMB11,PSMC5,PSMB6,PSMA2,PSMB3,PSMB7,PSMD3,PSMB1,HHIP,PSMA3,PSMB5,PSMC4,PSMD14,UBA52,UBB,PSMD10,PSME1,SPOPL,PSMD7 |
| 1.012e-04 | -9.20 | GAPVD1 (GTPase activating protein and VPS9 domains 1) | protein interactions | 26130 | 171 | 71 | 19454 | 5460 |
PSMC1,HSPA5,KDM1A,SNX24,SMC4,STAU1,TXNL1,HSPA8,SQSTM1,EP300,SIRT7,CSNK1A1,ACACA,PSMB7,VAV2,CSNK1A1L,GTF3C4,DUSP22,SF3A1,APEX1,VIRMA,ESR2,CPT2,MED17,FBXO22,ADRM1,PSMC5,GSK3A,PRMT5,PHF21A,LMBR1L,CCNF,TSSK1B,PSMA6,UBE2H,YWHAZ,IVNS1ABP,BRCA1,PSMD1,GGH,MCM4,CUL3,SFN,MCM6,VTA1,DUSP19,AHCYL1,RAD21,ARL5B,KPNA2,FBXO11,BAG2,PDIA6,FAF1,PSMC3,CSNK1E,EGLN3,SUMO2,PRNP,COPS2,RAB35,EEF1AKMT3,CBL,YWHAB,HSPB1,USP15,YWHAG,XPO1,COPS5,YWHAH,PSMD3 |
| 1.013e-04 | -9.20 | lymphocyte activation | biological process | GO:0046649 | 476 | 178 | 18204 | 5365 |
NCK1,TOX,IL2RG,CCND3,CTNNB1,RAB29,BAK1,PIK3R3,EP300,NOTCH2,TNFSF18,RPL22,SLAMF9,IFNA13,CCR6,NCR3,CCR7,RNF8,STAT6,AKAP17A,RABL3,PPP3CA,PTPN22,LCP1,RAB27A,SYVN1,FOSL2,IRF8,HDAC5,PRKCB,BST2,SKAP2,CD151,FKBP1A,DNAJB9,DLG1,MSN,IGBP1,LAT2,IL2,MSH6,EFNB1,NDFIP1,KIT,CCL21,IFNA10,CD86,TRAF3IP2,BAX,RSAD2,IL6,FCER1G,IL12B,FOXP1,STOML2,ITM2A,PELI1,TNFSF8,NFIL3,FOXP3,HSPD1,LILRB1,CD79B,SASH3,CD83,MEF2C,ST3GAL1,FKBP1B,SWAP70,CD28,CD80,CBFB,RC3H2,WNT10B,IFNB1,SOCS3,IFNA2,CD4,CD81,PSEN1,PDP2,PSMB11,IL4,ALKBH5,JAK1,IFNK,IL20RB,EMP2,PSMB10,VAMP7,SELENOK,PHB1,CMTM7,TESPA1,TUSC2,GPAM,SMAD3,RBPJ,IL10,CD2,LMBR1L,STK11,BATF,FCGR2B,PKNOX1,BCL6,CD40,HMGB1,TOP2B,SYK,CD1D,TBC1D10C,GPR89A,SLC25A5,IL15RA,RAG1,VAMP2,IL2RA,RHOH,DPP4,IRF4,NHEJ1,CCL19,CD1C,CEBPG,GJA1,CD38,CD2AP,LEPR,SLC39A7,CLEC7A,AZI2,IL21,ICAM1,IDO1,TP53,PIK3CG,CDK6,LRRC8A,CD40LG,LEP,TLR4,PHB2,MICB,DCLRE1C,FGL2,PRDX1,NKAP,IL18,PRDX2,ITK,IL7,EZH2,CHRNB2,EXOSC3,IL23A,KDELR1,B2M,NCSTN,EGR1,GAPT,IL15,FBXO7,TICAM1,PTGER4,CD247,NBN,LIPA,JAML,TNFAIP8L2,IRF1,SLA2,PRKCQ,TPD52,PIK3R1,HELLS,PIK3R2,CD3G |
| 1.014e-04 | -9.20 | GTF2B (general transcription factor IIB) | protein interactions | 2959 | 128 | 56 | 19454 | 5460 |
JCHAIN,POLR2D,POLR2C,POLR2G,GTF2E2,PSMB9,JUN,MED9,TP53,VDR,FBXO25,LSM4,KRAS,DHX9,TCEA2,MED4,TAF9,MED21,GTF2E1,WWP2,PRPF18,LSM5,POLR2I,TRAM2,DUSP6,GTF2B,CTBP1,RPA2,GTF2H4,ADRB2,MED11,TCEA1,PSMA3,RAB5A,EP300,PML,RPA3,UBE2H,RIT1,BAX,SERPINB1,ATG3,MECP2,DRAP1,RFC5,ALKBH2,ATF4,CREBBP,RPL10,TAF11,SMURF1,POLR2B,GTF2F2,POLR2F,GTF2F1,PSMC5 |
| 1.016e-04 | -9.19 | ZMYM2 (zinc finger MYM-type containing 2) | protein interactions | 7750 | 257 | 100 | 19454 | 5460 |
SMAD4,CRBN,FOXP1,USP15,ZNF24,KCTD15,H2AZ1,ETV6,SMAD3,MYBL2,ZNF280B,ACOT13,UBE2B,CBX3,CHAMP1,ZBTB26,TP53,ZMYM4,ZMYM3,H2AX,ZSCAN5A,H3C1,ZNF451,SNIP1,DNAJC10,NR2E1,CSK,TAF5L,AR,CEBPE,VIRMA,TUBA1B,CREB1,MACROH2A1,UBE2I,TRIM24,KIAA1958,FGFR1,RPA2,ZNF770,E2F6,HNRNPH3,SUPT7L,SUMO1,PCK2,KLF12,GTF3C4,KDM1A,GTF2I,HDAC3,POLDIP2,PIAS1,TRIM10,PML,ZKSCAN1,RPA3,DERL1,ARL14EP,NOL4,SUMO3,SUMO2,C1QTNF1,TRIM35,HMG20A,SIN3A,EED,NXT1,HDAC11,TUBB4B,MTA2,ZNF263,ZNF397,SOX2,RBBP7,PCGF6,PAX6,FOXP4,GTF3C3,UBE2A,MATN4,HNRNPA2B1,PSMD14,CUL3,CREBBP,MYC,DYNLL1,RBBP4,MAD2L2,ESR2,ZNF174,PHF21A,ZMYM2,ADNP,UBAC2,GTF2IRD1,CTBP1,KLF3,ZNF362,FOXP2,ZBTB5 |
| 1.016e-04 | -9.19 | WWP1 (WW domain containing E3 ubiquitin protein ligase 1) | protein interactions | 11059 | 257 | 100 | 19454 | 5460 |
SFTPC,CDK8,POLR2G,RPSA,TP53,SMAD1,RPAP2,WASL,THRAP3,HNRNPK,EGR1,ARF4,ILDR1,SNAP23,RPL3,RPL24,SLC2A1,SMAD4,RPL10A,MZT2B,DAG1,POLR2I,CD151,RPS16,HRAS,EEF1B2,SMAD3,WWP1,STAT6,MACROH2A2,LITAF,PRRG1,PIP4P1,LRP10,BAP1,DVL2,RTN4,TXNIP,TMEM255A,SMAD2,NONO,PCBD1,RUNX1,TXN,RAB14,PYGM,SMAD5,SMURF1,UBE2L3,EIF4A3,PTEN,EZH2,PLD3,RPS11,POLR2D,POLR2C,TOP3B,RPS7,H1-6,NFE2,FLOT1,RPS27A,RPL28,FAM168A,ERP29,SETD4,EWSR1,LDLRAD4,TRAF6,UBE2D1,HSPB1,BCL2L1,CBL,WWP2,HNRNPA1,ATXN10,HNRNPL,SRSF1,RPLP2,CORO1C,NUFIP2,IL2RG,PHB2,UBE2D3,RNF11,XRCC5,WBP2,ARRDC3,ICA1,HSP90AA1,NDFIP1,MATR3,ERH,RPL10,ESR2,RPL19,POLR2B,FAU,RPS9,LRP12 |
| 1.016e-04 | -9.19 | REXO4 (REX4 homolog, 3'-5' exonuclease) | protein interactions | 57109 | 257 | 100 | 19454 | 5460 |
H1-5,SF3B1,CCDC86,MRPS7,ZNF692,STAU1,ZNF668,MYC,RAB11A,H1-1,NSA2,ZCRB1,MRPS25,FTSJ3,RPL37A,ZNF22,ZNF189,ESR2,RPL19,APEX1,RPL7L1,RPL35,SNRNP40,SOX2,H1-3,RAF1,MAGEB10,RPL18,GLE1,RPS24,RPL31,PPAN,SRSF4,RPL28,PAX6,H1-6,DDRGK1,IFI16,BAZ1B,LHX2,ZCCHC9,DDX23,HP1BP3,RPL8,SRSF1,RPS10,LYAR,KLF12,RPS14,RPLP0,RPL26L1,ZNF574,MACROH2A2,LMNA,CCDC106,RAB9A,SIRT7,PML,NLE1,UTP23,RPS15,DGCR8,NPM3,RPL4,RPL26,RPF2,SMARCA5,RPL7A,CASC3,RC3H2,FGFBP1,PRKRA,ZNF330,SRPK2,BUB3,RPL13A,AURKAIP1,H2AX,RPL15,CBX3,LLPH,RBM34,RPL3,SNIP1,RPL17,H3C1,IMP4,MOV10,GRSF1,CMSS1,RPL10A,MPHOSPH10,ARL4D,SRP14,RPL32,KRR1,DKC1,MDM2,SURF6,ZNF7 |
| 1.017e-04 | -9.19 | TES (testin LIM domain protein) | protein interactions | 26136 | 327 | 123 | 19454 | 5460 |
RFC4,ATP5F1E,EP300,HADHA,TGFB1I1,CSRP1,UNC45A,LAP3,TOR1AIP2,PPP1CB,PLAA,ACAA2,TBC1D17,MYL6,RDH12,ARCN1,AP2M1,ATP5F1B,TAGLN2,STAT1,MB21D2,TUBB,ACTB,ATP6AP2,APEX1,ERH,NFYA,CUL3,ICAM1,OSGEP,ZYX,ALKBH4,FHL3,LASP1,UBE2A,RAB8B,AHCYL1,SACM1L,ACTN4,CTNNA2,TUBB4B,PDHA1,JPT2,OTULIN,LIMD2,DNM2,IFIT2,CORO1C,IGBP1,MAGED2,KRT8,TNFAIP8L2,SPTAN1,HSP90AB1,CCT7,PSMD3,CTNNB1,SIAH2,CRTAP,HAX1,AHSA1,HSPB1,AVL9,RPA3,PML,RNF113A,SQSTM1,H2BC12,AIF1L,FBXW7,PCK2,SPTBN1,ARHGAP1,MYL12B,CFTR,RPA2,CDK1,RPRD1B,TCP11L1,PRKCA,KRT7,SCLT1,CCNF,CTNNA1,TUBA1B,CTTN,SRP54,ARMC6,SH3BGRL,SH3BP4,DYRK1A,RAB2A,CFL1,TUFM,BICD2,EPHA2,SERPINB1,CDC73,UBE2H,CALU,PALM2AKAP2,PC,IGF1R,TRAFD1,HUWE1,SRPRB,THRAP3,TP53,SOCS3,MAP2K3,NECAP2,TFRC,ARPC3,AIFM1,ACTA2,TES,PPP1R18,SNN,MOV10,PGAM1,FCGR2A,H2AC4,CNN3 |
| 1.018e-04 | -9.19 | FLT4 (fms related receptor tyrosine kinase 4) | protein interactions | 2324 | 254 | 99 | 19454 | 5460 |
APMAP,ITM2B,PIK3R2,TMEM209,HSPA5,MRPL10,NTPCR,CNP,CDK1,SEC61A1,EIF2S2,MSN,COPE,SEC63,SMARCA5,PTPN11,SDF2L1,ARFGAP3,LGALS8,EPHA2,XPOT,MRPS18B,DNAAF10,SRPRB,SLC6A8,ARF4,DUSP19,STRBP,CHRM3,DDX39A,PTPN1,MRPS9,SRPRA,AIP,UBE2N,SEC23A,FZR1,ARF6,ILVBL,MRPS23,KARS1,CALR,CXCL13,LRRC40,SHC1,OSBPL8,TTC1,FXR2,UNC45A,NOTCH2,NPY2R,RAB6A,VAPB,SLC25A3,ARCN1,PIH1D1,MRPL23,LGALS3,POLR2B,MAD2L1,ALG5,VEZT,SLC1A3,FBXW11,HSP90AA1,SCFD1,SERPINH1,NDUFA4,BAG2,FHL3,TNF,TFG,SAR1B,TRMT1L,NUDCD3,NUP37,STIM1,NUDT19,PLD3,PTK7,MRTO4,PBDC1,XPO5,MAGED2,EIF2S1,CX3CL1,SNX2,CACYBP,HSP90AB1,VEGFC,PDIA3,PIK3R1,STOML2,SHC3,DDRGK1,CDK5RAP3,NCK1,HAX1,AHSA1 |
| 1.021e-04 | -9.19 | CAPNS1 (calpain small subunit 1) | protein interactions | 826 | 114 | 51 | 19454 | 5460 |
TENT5C,FERMT2,MAT2B,CDC20,APEX1,CCNF,SPOP,YWHAZ,UBE2H,MAT2A,EMC1,ADRB2,HSPA5,RPA3,ARHGEF6,STK26,PAK2,ADSS2,RPA2,ISOC1,WWP1,PIH1D1,IL2RG,CFAP418,CAPN1,AGTRAP,PAFAH1B1,CDC42,CDK7,CFTR,SSBP1,AGR2,SHC1,POU5F1,DRG1,MAP4,WWP2,YWHAG,YWHAH,GAPDH,TNF,HUWE1,RUVBL1,MEPCE,DUSP19,RAB1A,CAPN2,GNAI3,RAF1,CDK4,FNTB |
| 1.021e-04 | -9.19 | CWC15 (CWC15 spliceosome associated protein homolog) | protein interactions | 51503 | 114 | 51 | 19454 | 5460 |
SNRPA,SLU7,DDX39B,SF3B1,HSPA8,SRSF2,ATG16L1,SF3A1,PCK2,TFIP11,EIF4A3,DLST,SNRPD1,SF3B4,SNRPD2,SNRNP40,FBXO22,SNRPB2,MYC,USP13,HNRNPC,CUL3,SNRPB,ARMT1,SNIP1,HNRNPA2B1,EWSR1,SOS2,TSSC4,CTNNBL1,RIGI,RAF1,E2F4,FNTB,EZH2,PDHA1,ILF2,SF3B5,SNRPE,SRSF1,SNRPD3,SNRPA1,PRNP,TOP1,CDC5L,PRPF19,RBM17,HNRNPA1,DDX23,SNRNP70,MAGOH |
| 1.021e-04 | -9.19 | RNF40 (ring finger protein 40) | protein interactions | 9810 | 248 | 97 | 19454 | 5460 |
USP15,MED21,H2AC4,KXD1,NCBP2,CDK9,DCUN1D1,CAND1,TSC22D3,THOC1,OLFM2,NELL2,PSMB1,RB1,PTPN1,ALYREF,UBE2N,PSMC3,DISC1,UBE2B,SNAP29,TP53,RNF20,PDRG1,RIGI,CTNNBL1,THRAP3,ZC3H11A,TFPT,ZNF451,CDC73,NAPA,SPOP,PKNOX1,FBXO7,BRAP,ZCCHC12,AR,AKT1,ROCK1,UBB,VIRMA,MAGOHB,POLR3H,UBE2I,STUB1,LURAP1,WTAP,ZNF326,FBXL19,HSPA5,KDM1A,OIP5,MED4,STX1A,SKIC8,INSYN1,PRPF19,IFI16,EGLN3,WIF1,CCT7,G0S2,SNX2,PLEKHO2,RHOBTB1,TRAF2,RBM12,TOP3B,SUPT5H,UBE2A,MSL2,KRAS,XPNPEP1,EWSR1,HSP90AA1,PFDN2,CCT2,RNF40,ATG101,MYC,DSN1,ERH,SMU1,PHF21A,CMTR1,UBE2S,GTF2H5,EIF4B,TPD52L1,IER2,INSYN2A,BORCS6,NUP62,MCMBP,DDX5,EP300 |
| 1.022e-04 | -9.19 | ARID1A (AT-rich interaction domain 1A) | protein interactions | 8289 | 245 | 96 | 19454 | 5460 |
SKP1,SAP18,FOS,SMARCD3,DDIT3,NUP50,EP300,NUBP2,HSPA8,ADNP,RNF7,KLF3,ELF5,ATP6V1C1,ACTL6A,ETF1,SNRNP40,ACTB,RBBP4,PRMT5,BRCA1,CUL2,HNRNPC,CUL3,MYC,HNF1B,CREBBP,IRF1,SMARCE1,ASF1A,RUVBL1,RBBP7,SSRP1,PAX6,TOP2B,BCL7B,EWSR1,EZH2,SMARCB1,MTA2,SUPT5H,TOP3B,SAP30,ACTN4,SOX2,HNRNPL,PGR,NUP35,MRTO4,PHB1,SIN3A,PTGDS,BRD9,EED,LHX2,WWP2,BAZ1B,ATG7,BCL7C,USP8,NUCKS1,SS18,MBD3,SIRT7,RPA3,ELOF1,RPA2,KLF4,PAX9,VIRMA,CCNF,MACROH2A1,PTEN,ZMAT5,SMAD2,CCDC174,AR,RUNX1,MDC1,SNIP1,HAPSTR1,IK,TP53,SOX9,H2AX,EGR2,ING1,TOP1,KLF1,CDC5L,SMAD3,H2AC4,BRD3,TOPBP1,IRF4,MOV10 |
| 1.022e-04 | -9.19 | regulation of interleukin-1 production | biological process | GO:0032652 | 128 | 58 | 18204 | 5365 |
MIR98,CCR7,TLR6,AGER,MIR361,PYCARD,TLR4,HMGB1,NLRP1,CCL3,MIR132,TNFAIP3,SERPINB1,IL6,CLEC7A,GSTP1,CX3CR1,MIR920,PYDC2,TMEM106A,HSPB1,MIR877,MIR142,IGF1,FOXP1,TNF,MIR101-1,CX3CL1,SMAD3,IL10,IFNG,MIR144,IFI16,LILRA2,TLR8,CCL19,LILRB4,IL1R2,MIR181D,GHRL,MIR206,NLRP3,MYD88,MIR195,ARG2,CD36,MIR488,NLRP2,RAD21,TYROBP,JAK2,CPTP,MIR181C,EGR1,ACP5,PML,MIR204,MIR708 |
| 1.024e-04 | -9.19 | positive regulation of angiogenesis | biological process | GO:0045766 | 186 | 79 | 18204 | 5365 |
CD40,IL1B,FUT1,MIR1224,AKT3,MIR132,DDAH1,MIR99B,TNFSF12,RHOB,GREM1,APLNR,VEGFC,EMC10,ZNF304,MTDH,CXCR4,ITGB8,SEMA5A,EMILIN1,CCL11,KLF4,IL10,TLR3,IL1A,CXCL8,CCR3,MIR143,HSPB1,CAMP,BTG1,CCL24,CX3CR1,MIR1-1,MIR126,MIR31,RLN2,CYP1B1,BRCA1,JAK1,AGGF1,JUP,GHRL,ADM2,RUNX1,MIR20A,EMP2,XBP1,GAB1,NR2E1,PRKCA,MIR30A,NINJ1,MIR30B,MIR378A,MIR21,TGFBR2,MIRLET7B,FOXC2,STIM1,MIR130A,SP1,NRP1,FGF1,MIR125A,JMJD8,CHI3L1,NFE2L2,SMAD1,HSPB6,CD34,CHRNA7,MIR29A,MIRLET7G,VEGFA,TERT,PRKCB,CMA1,MIR210 |
| 1.030e-04 | -9.18 | CENPC (centromere protein C) | protein interactions | 1060 | 92 | 43 | 19454 | 5460 |
MIS12,RPL3,RPS24,RPL31,NLE1,RPL28,COIL,MDC1,DGCR8,H3C1,ASF1A,RPL4,NUP153,RPL15,H1-5,CENPM,RPL18,MACROH2A2,CBX3,RBM34,EED,PRKRA,PTEN,ACTA2,ZNF330,CDC5L,APEX1,NUF2,SNRNP40,SUMO2,PRNP,RPL13A,HNRNPA1,ELOC,DNAJC8,MYC,DSN1,CIAO1,NDC80,BRD3,DDX23,CHTOP,DCAF4 |
| 1.030e-04 | -9.18 | POLR3H (RNA polymerase III subunit H) | protein interactions | 171568 | 92 | 43 | 19454 | 5460 |
UPRT,POLR1D,RPRD1B,PIH1D1,UBE2M,PDCL,ATPAF2,PRIM2,HSPA5,CDC42EP4,POLR1H,HSPA14,RNF40,SAMHD1,PFDN6,POLR1B,RIT1,ELAVL2,PFDN2,POLR2F,POLR3B,POLR2B,TRMT1L,RPAP2,POLR2D,POLR2C,POLR2G,IDH1,RPAP3,DNAAF10,KRAS,RNF20,PDRG1,POLR3GL,MED4,POLR2L,RPRD1A,SNX17,POLR2I,SPPL3,KIF3B,PGR,POLR3F |
| 1.032e-04 | -9.18 | MYH14 (myosin heavy chain 14) | protein interactions | 79784 | 174 | 72 | 19454 | 5460 |
CFTR,H1-5,MYL12B,MYL6,RPA2,METTL14,STX17,RPA3,DDX39B,INPPL1,SIRT7,PML,FOS,CHMP2B,UNC45A,UFL1,PIK3R2,SRI,FBXW7,SSR3,STAU1,BTF3,PDE4B,AR,USP14,CCNQ,MYC,CUL3,RPL7A,CDC73,SP1,BRCA1,CCNF,DLST,ELK3,SH3BGRL,STAT1,MATR3,SNAPIN,OTUD6B,SOX2,LGR4,FCF1,FBP1,RAF1,RNF181,TFCP2,EZH2,IRF8,KLF10,FBXO25,PSMB10,DPM2,MDC1,TNF,PSMA1,H3C1,TRIM37,RUVBL1,HDAC6,CTNNB1,IFI16,ANKRD50,AGR2,SHC1,MYL12A,CDK9,TMPO,PTP4A3,SRSF10,POLE3,HNRNPL |
| 1.032e-04 | -9.18 | KAT2A (lysine acetyltransferase 2A) | protein interactions | 2648 | 174 | 72 | 19454 | 5460 |
H2AC4,BECN1,EID1,SMAD9,KPNA1,TAF9,ENY2,CTNNB1,HDAC6,GRM1,FZR1,ARF6,SMAD3,LDLR,CDK6,NME1,CDK8,TAF10,RBPJ,SF3B5,E2F4,TP53,TOP3B,MAX,WDR37,IKZF5,ELF1,SMAD1,MAP2K3,H2AX,H3C1,PTGES3,POLE4,HAPSTR1,TADA3,TADA1,DTL,STK11,SMAD2,CUL2,TAF5L,MYC,CREBBP,SMARCA5,AKT1,IRF1,MED17,TUBB,LDHA,SMAD5,ESR2,MAD2L1,IRF2,UBE2I,CTBP1,PPARG,KLF3,SUPT7L,PLAC1,ACTL6A,H1-5,KLF12,XBP1,TIRAP,SUPT3H,KDELR2,NF2,SGF29,IRF7,XRCC5,DR1,EP300 |
| 1.035e-04 | -9.18 | POLR1H (RNA polymerase I subunit H) | protein interactions | 30834 | 68 | 34 | 19454 | 5460 |
RPRD1A,POLR2L,POLR3B,POLR2F,UBE2I,POLR3H,POLR2I,POLR2B,ZNF593,RRN3,NONO,IL15,IVNS1ABP,PFDN2,HAX1,MED4,POLR1B,PFDN6,TCOF1,RPAP3,FHL3,DNAAF10,PDRG1,POLR1H,RPAP2,DUSP1,SERPINA3,POLR1D,RPRD1B,POLR2C,POLR2G,POLR2D,TAF2,PIH1D1 |
| 1.035e-04 | -9.18 | DFFA (DNA fragmentation factor subunit alpha) | protein interactions | 1676 | 68 | 34 | 19454 | 5460 |
NUDT5,EWSR1,ROCK2,GTF2I,UNC45A,GNB4,TOM1L2,TUBA1A,ISOC1,NFE2L2,BZW2,NAP1L5,IL18,PRNP,TUBB,UBA3,ROCK1,PPP5C,FERMT2,EGLN3,TSPYL4,MAT2B,FAM118B,BAK1,CIDEB,MAT2A,MOV10,GAPDH,YWHAG,YWHAZ,ATG3,CKB,USP15,HSPB1 |
| 1.035e-04 | -9.18 | GET4 (guided entry of tail-anchored proteins factor 4) | protein interactions | 51608 | 148 | 63 | 19454 | 5460 |
HSP90AB1,CCT7,ATP5PD,EGLN3,AIFM1,RAB3A,EXOC2,AGR2,EDEM1,DNAJB2,MOV10,ENKD1,DUSP21,HUWE1,PSME1,CCT8,FAF1,MAP1B,RNF126,MTA2,SOD2,PLS3,CDK8,KIF2A,ERLIN2,FAF2,TUBA1A,MTCH2,CCT5,TOP3B,UBL4A,TAX1BP1,SEC61B,SGTA,PSMC5,LMBR1L,ABCG2,PSMD14,CCT2,UFD1,BTF3,FBXO7,AKT1,USP13,LSM8,EEF1G,GTF2I,TTR,DDX5,TMEM256,SCN1B,FLYWCH2,RPA3,HEXIM1,EIF4B,GIT2,GRM2,UBAC2,RPA2,VAPB,SDCBP,CDKN1A,PRMT2 |
| 1.046e-04 | -9.17 | PCP/CE pathway | REACTOME pathways | R-HSA-4086400 | 96 | 48 | 10285 | 3229 |
AP2S1,SMURF1,PSMA6,PARD6A,AP2M1,PSMB2,PSMD1,DVL2,PRKCB,PSMC1,FZD6,PSMD12,PSMA1,PSMC3,MIR937,PSMD4,FZD3,RPS27A,PSMB4,PSMD6,PSME2,RAC2,SEM1,PSMB9,PSMA5,PSMB10,PSMC5,PSMB11,PSMA4,PSMB3,PSMA2,AP2A1,PSMB6,PSMB1,PSMB7,PSMD3,PSMC4,PSMA3,PSMB5,DAAM1,PSMD14,UBB,PRKCA,UBA52,PSME1,PSMD10,FZD4,PSMD7 |
| 1.050e-04 | -9.16 | Toll/interleukin-1 receptor homology (TIR) domain | gene3d domains | 3.40.50.10140 | 26 | 17 | 14470 | 4137 |
TICAM1,IL1RAP,SARM1,PIK3AP1,TLR5,TLR6,MYD88,TLR8,TLR9,TLR10,TIRAP,TLR1,TLR3,TLR7,TLR4,TICAM2,TLR2 |
| 1.055e-04 | -9.16 | sphingolipid biosynthetic process | biological process | GO:0030148 | 104 | 49 | 18204 | 5365 |
ELOVL7,B4GALT4,HACD1,SPHK2,ELOVL6,CLN8,ELOVL1,SMPD2,ST3GAL1,UGCG,ACER3,SPTSSA,B3GALT2,FUT9,HACD3,ST8SIA5,B4GALT3,AGK,ST3GAL5,KDSR,SGMS2,ORMDL1,ST3GAL2,B4GALT6,B3GALT4,CYP4F22,B3GALNT1,ELOVL4,ST8SIA4,TLCD3B,ST6GALNAC3,OSBP,HACD2,PRKD3,CERS2,SGMS1,ELOVL3,CERS6,FA2H,DEGS1,CERK,FUT1,LARGE1,GAL3ST1,ORMDL3,HACD4,SPTSSB,ABCG2,B3GALT1 |
| 1.058e-04 | -9.15 | mRNA 3'-end processing | REACTOME pathways | R-HSA-72187 | 62 | 34 | 10285 | 3229 |
UPF3B,CHTOP,THOC2,MAGOHB,THOC3,CSTF3,POLDIP3,SLU7,NCBP2,PAPOLA,MIR939,DDX39B,CPSF1,FYTTD1,EIF4A3,DDX39A,CDC40,ALYREF,SRSF1,DHX38,CASC3,MIR636,SRSF7,SRSF2,ZC3H11A,CPSF2,CLP1,SRSF4,MAGOH,THOC6,CPSF4,THOC1,CSTF2T,MIR1234 |
| 1.060e-04 | -9.15 | CRMP1 (collapsin response mediator protein 1) | protein interactions | 1400 | 131 | 57 | 19454 | 5460 |
NDUFV2,ZNF24,CNN3,HAX1,CBL,AGR2,CDK5RAP3,ARMC1,SWAP70,CCT7,EXOSC8,TUBA1A,OTUD6B,SERPINB9,ARFGAP1,HGS,DISC1,UBE2B,DNAJB4,SNRPG,SEPHS1,NAT9,TFG,UBE2A,HSPE1,TOM1,RGL2,RSPH1,RRP7A,YAE1,CRMP1,FAS,EIF2S2,LRRC1,MOB4,PAFAH1B3,SRC,ROCK1,TUBB,FTH1,PPP1R8,UBA52,ANXA7,CCL18,ARL15,HNRNPH3,LSM2,FGFR1,PPT1,RPA2,RTN4,CCDC106,SAT1,RGS2,GPM6A,PITHD1,HMGB1 |
| 1.060e-04 | -9.15 | TBCD (tubulin folding cofactor D) | protein interactions | 6904 | 131 | 57 | 19454 | 5460 |
NPTN,CRYL1,RPA3,PRKCB,HSPA8,MTDH,TCP11L1,RPA2,CTDSP1,SH3GLB2,KLC2,FAM234A,HCST,STAT1,TUBB,TSN,NMI,SCN2B,LMBR1L,CCNF,S100A6,GTF2A1,RIT1,GPR17,TBCE,CUL3,SCN3B,GORASP2,KRAS,TOM1,IMMP2L,OSTM1,ABCE1,BAG2,TUBB4B,CAPN2,APEH,TOP3B,IL1R2,TUBA1A,ACTN4,MGARP,FAF2,HNRNPL,SNX2,PRNP,POLR2I,WDR12,NCR3LG1,PDCD1,VCPIP1,SMAD9,MAP4,DEXI,LRRC4,ATG7,TPM3 |
| 1.065e-04 | -9.15 | TMCC1 (transmembrane and coiled-coil domain family 1) | protein interactions | 23023 | 22 | 15 | 19454 | 5460 |
MAPRE1,YWHAB,YWHAZ,YWHAH,YWHAG,SFN,ZDHHC17,CBX5,ESR2,VIRMA,RIGI,APEX1,DNAJC1,HNRNPL,PTPN1 |
| 1.065e-04 | -9.15 | E2F8 (E2F transcription factor 8) | protein interactions | 79733 | 22 | 15 | 19454 | 5460 |
ZDHHC17,IFRD2,FHL3,OR1M1,EWSR1,STUB1,CCNF,STAT6,YWHAB,YWHAZ,TFCP2,TTC33,NONO,YWHAG,YWHAH |
| 1.065e-04 | -9.15 | CACUL1 (CDK2 associated cullin domain 1) | protein interactions | 143384 | 22 | 15 | 19454 | 5460 |
H2BC17,SPOP,HBB,CSNK1G3,CSK,KBTBD4,RAP1A,AR,KPNA6,PSMA2,SOCS2,PML,CALML5,NUP50,UBE2I |
| 1.066e-04 | -9.15 | positive regulation of vasculature development | biological process | GO:1904018 | 189 | 80 | 18204 | 5365 |
JMJD8,FGF1,MIR125A,NRP1,HSPB6,SMAD1,NFE2L2,CHI3L1,MIR29A,CHRNA7,CD34,MIR210,CMA1,PRKCB,TERT,VEGFA,MIRLET7G,AGGF1,JUP,BRCA1,JAK1,CYP1B1,RLN2,MIR31,PRKCA,NR2E1,GAB1,XBP1,EMP2,MIR20A,GHRL,ADM2,RUNX1,MIR30B,MIR21,MIR378A,NINJ1,MIR30A,SP1,STIM1,MIR130A,FOXC2,MIRLET7B,TGFBR2,TLR3,IL1A,IL10,CCR3,CXCL8,CCL24,BTG1,CAMP,MIR143,HSPB1,MIR1-1,MIR126,CX3CR1,MIR132,CXCL12,AKT3,MIR1224,IL1B,FUT1,CD40,TNFSF12,MIR99B,DDAH1,MTDH,ZNF304,EMC10,VEGFC,APLNR,RHOB,GREM1,KLF4,EMILIN1,SEMA5A,CCL11,CXCR4,ITGB8 |
| 1.066e-04 | -9.15 | regulation of production of molecular mediator of immune response | biological process | GO:0002700 | 189 | 80 | 18204 | 5365 |
CCR2,IL2,VAMP3,LITAF,IFNA2,DNAJB9,CD81,LILRB4,XBP1,TNFRSF1B,TLR9,TNFSF13,TRAF6,MYD88,NLRP3,NDFIP1,KIT,IL4,LACC1,CD36,B2M,SEMA7A,CD28,CGAS,EXOSC3,TNFRSF14,IL5,MAD2L2,IFNB1,HMCES,TICAM1,RIGI,TLR7,MAVS,ACP5,BST2,SPHK2,PHB2,FCGR2B,STAT6,KLK3,PYCARD,MZB1,CD40LG,TLR4,SASH3,SYK,MIF,IL18,FOXP3,HFE,BCL10,HTR2A,BCL6,ANGPT1,CD40,TGFB3,LILRB1,IL1B,TMBIM6,TRAF2,IL21,RSAD2,SHLD1,CLEC7A,IL6,KMT5B,CD86,KLK5,TRIM6,PHB1,TFRC,IL13,TNF,IL17F,TLR3,TGFB2,DDX1,IL10,XCL1 |
| 1.067e-04 | -9.15 | RHOBTB1 (Rho related BTB domain containing 1) | protein interactions | 9886 | 151 | 64 | 19454 | 5460 |
SSX2IP,KPNA1,MPHOSPH10,SLC2A1,TPM3,COPS5,GRSF1,CCT7,CACYBP,ERLIN1,COPS7B,COPS2,XPO5,WDCP,RHOBTB1,SF3B5,POLR2C,RBPJ,JCHAIN,PRKAG1,RPN1,RPL29,BPIFA2,SSRP1,COPS4,APBB3,RNF20,ROCK2,DHX16,NEDD8,HNRNPA2B1,TOP2B,THOC6,HSP90AA1,XPOT,H2AZ2,MYO6,CCT2,MRPL16,PSMD1,PRPF31,DEPDC1B,RNF40,TOMM40,CUL3,HNRNPC,COPS7A,SLC25A1,MYC,ROCK1,MACROH2A1,GANAB,TUBA1B,HAUS2,SUPT7L,UBE2M,MEST,ETF1,COIL,NOP53,NSFL1C,STK38,TRA2B,TXNL1 |
| 1.067e-04 | -9.15 | OXSR1 (oxidative stress responsive kinase 1) | protein interactions | 9943 | 151 | 64 | 19454 | 5460 |
OARD1,ANP32A,CCR1,RELL2,BAG2,RNASEH2C,TMEM87A,RPL17,TGFBR2,API5,BTF3L4,RPAIN,MSTN,TSPAN10,CFC1,BMPR1B,UBXN6,RELL1,GSTM3,AGPAT1,DDX1,ARL4D,EEF1AKMT3,AIFM1,ELSPBP1,WDR6,WIF1,CDC5L,CDK9,DNAJB9,RPL35A,TRIM35,HNRNPL,SNRNP27,RFXANK,TANK,ATG16L1,ACACA,ARL15,SLC12A2,RPA2,EP300,SQSTM1,HSPA8,PML,LGI1,THUMPD1,RPA3,MARS1,STAU1,HSCB,WDR3,GGH,SFN,AKT1,OAT,CHCHD4,RHOB,ESR2,USP5,MAD2L1,SMURF1,TENT5C,COPE |
| 1.067e-04 | -9.15 | POLR3D (RNA polymerase III subunit D) | protein interactions | 661 | 84 | 40 | 19454 | 5460 |
DCAF8L2,RPRD1B,RPA2,POLR2D,POLR2C,POLR2G,PIH1D1,RBFOX2,TRMT1L,POLR1D,RPAP2,MSX2,KRAS,DNAAF10,GTF3C3,PDRG1,POLR1H,RPA3,ATF3,RPAP3,HSPA8,MED4,PFDN2,PFDN6,MAF1,POLR1B,MYC,HNRNPAB,XPO1,POLR3GL,POLR3F,TAB1,POLR2I,POLR2B,APEX1,RPRD1A,POLR2L,POLR3B,POLR3H,POLR2F |
| 1.067e-04 | -9.15 | IFNGR1 (interferon gamma receptor 1) | protein interactions | 3459 | 84 | 40 | 19454 | 5460 |
RHOU,BMPR1A,RUSF1,LRP10,JAK1,KRAS,STX7,IFNG,CDC42,RND2,IFNGR1,STIM1,SDCBP,FGFR1,CTXN1,IL20RB,TSPAN3,STUB1,HRAS,HCLS1,TMEM74,NRSN1,CX3CL1,STAT1,RHOH,RHOJ,NDFIP1,SRC,CAV1,JAK2,TMEM237,MAD2L2,MOV10,DPP4,PTPN11,RAB11A,IFNAR1,RHOG,RHOB,TMEM100 |
| 1.070e-04 | -9.14 | regulation of cellular process | biological process | GO:0050794 | 11468 | 3490 | 18204 | 5365 |
LBH,CCR3,OR2J3,H2AZ1,FBXO31,TRAF2,CBX5,MRGPRX2,HRH3,NMBR,RPS3,EEF2,TMEM106B,TRIM6,ETF1,H1-1,FOXP4,CORO1C,STX1A,EPHA2,OR5M9,CAB39,LARP4B,PLEKHF1,ERAS,TAPT1,RHOB,MIR361,AGER,CFDP1,RPF2,CXCL10,CIDEB,ATG3,SPHK2,GPR176,RAG1,FBXW11,SPINDOC,H2AX,OGG1,SCN2B,RAB9B,DIS3L,OR5AN1,LDB1,AIPL1,STK38L,EXOC8,MIRLET7C,INA,SLC29A1,MIR1277,RHOH,UFM1,MIR657,DIPK2A,TAF7,SPPL3,MADCAM1,VPS72,KCTD20,ZNF671,IL13,MIR609,TMEM14B,MIR34A,VPS4A,HELT,VASH1,FGFR1,VGLL2,SCAMP5,MIR155HG,PIWIL4,HDAC11,HUWE1,CEP97,MICB,FAM3C,ENC1,NETO1,CKS1B,LRRC8A,FAM13B,GHITM,NONO,TFPT,SLC6A4,RAD21,CLN8,MYRF,CAPG,PYCR1,TPRA1,IER2,CHRNB2,RFXAP,MTRNR2L7,MIR1262,IL7,OR10G2,DCP2,ZBTB6,TSPO,RAP2A,TMOD1,AAMP,OR1S1,RNF187,GPNMB,JUP,MIR711,MIDEAS,JAML,NSDHL,RAB39B,CSNK1A1,KLHL12,RIMS4,RASL11A,NOTCH2,RBM7,SVIP,MIR144,PAK6,CLPB,FCN2,TGFB2,CHP1,PCNA,ATP5F1B,ZBTB38,PDE8A,TMEM115,USP13,HSBP1,FMO1,CDH13,FOLR2,SNX33,MTDH,ENHO,ADTRP,USP14,MMD,EDEM1,NCKAP1,PFDN2,TMOD2,TMEM170B,MIR708,CHGA,CTBP1,ZNF174,ZC3H14,MCHR1,RAP1B,CIRBP,PRCP,MIR20A,CFAP298,OR51M1,FZD3,TNR,IFI35,TAAR6,CISD1,CDK7,MAFG,PEG10,ATP6V0B,DOK6,GLO1,THOC2,TMSB10,IER3,TXNDC17,SNCB,TDRD7,IFNAR1,HSPB2,PSRC1,TRIM36,SASH3,PELI3,HTR2A,INPP5K,HSP90AA1,USP15,SYNDIG1,DAD1,SNAP25,WDR45,CDK5R1,TRIM11,PFDN6,ATP6V1A,SP4,ACHE,USP8,HTR1A,SMG5,CD28,PTPRZ1,HSP90AB1,FKBP1B,VGLL4,ZCCHC17,CAV3,TNFAIP8,BEND5,GFI1,CNKSR3,PKIG,TAF2,TCTA,WWP1,S100A11,ZGLP1,LILRB4,RPS27L,ARL6IP5,EGR2,HBEGF,ATG16L1,ELF5,IFIT2,MIR24-1,TEX19,KMT5B,KLRC2,TAF9,WNT2,CCN3,SELENOK,TRIM62,OR5V1,RALB,MIR599,ELP3,FCGR2B,STAP1,CHI3L1,TAFA1,KLRF1,FOS,IRF2BPL,PRSS37,FAM168A,KCNJ8,ARG2,DYNLT3,KCTD16,MIR937,P3H1,IGSF11,MRAS,MIR802,NUDT12,MIR181D,NAE1,TICAM2,TRAF6,HOXD12,LRTM2,RNF40,SYCE3,PDYN,TRIB1,NUDT4,STX5,PGRMC1,ZBTB5,TENT2,IFNG,TAB2,OAZ3,PDCL,TACR3,MTMR2,SRGN,FAIM,PTGES3,ANGPT1,ADRA1A,CDK20,FIBIN,PSEN2,HEXIM1,TRIM21,CD1A,AKR1C1,TICAM1,TAS2R39,SIGMAR1,UBL5,MIR181C,BMPR2,LYPLA1,SNCG,INSM2,RND3,PQBP1,CCT5,STARD4,NTRK2,FLRT2,IFI16,TLCD3B,METTL14,ACTR2,TCEAL7,NBN,BPIFB1,CTNNBIP1,RFC3,VDAC2,EP300,OVOL1,BACH1,PNMA5,ANXA7,IFT25,LSM14B,FAM53B,GMNN,CDC7,OR4B1,ZNF862,ZMYND11,MIR136,AKAP17A,MIR92B,MIR99A,GRB10,TANK,CEND1,SELENOS,DRD3,AMELX,LIMS2,CDKL2,ABRACL,TSPAN15,NPW,TIRAP,MIR573,MIR545,ADCY2,KPNA6,DEDD,B4GALT7,BAD,DERL1,HTRA1,SNX12,ADRB3,MIR206,GNG11,CDK12,TRIM24,RIC3,STOML2,MIR190A,MYO6,FOXP1,UBE3A,IL12B,DPP10,RNF14,PCBP4,DUOXA2,RSAD2,DLGAP4,ZFP64,BGLAP,PCDH17,MIR107,RTKN,PNP,JUN,RNF122,CBX3,MIR885,ROPN1B,HSPD1,MIR449A,MTA3,TMEM196,SLC1A3,EMX2,CXXC1,ZFP1,SIN3A,OR6X1,CHMP2A,RRAGB,CFC1,POLR3F,MIR210,OR8I2,MIR197,RMI2,ZNF592,RERG,MIR33B,RWDD1,MIR651,FMC1,TIA1,LST1,RGCC,MYBL2,LILRA2,MIR375,HADH,RBFOX3,ECRG4,CD9,MTG2,VAPB,CAMK2N1,NDUFAF2,NGRN,TBCCD1,MIR1298,TESPA1,ANP32A,RPA2,ERLEC1,STUB1,GOLPH3L,PNMA2,KCNMA1,HEXIM2,MIR615,CXCL12,PLAC8,OR8G5,KDM2A,CHRDL1,CCT8,TOP1,MED4,SUPT5H,MDFI,MIR105-1,ZNF655,TAFAZZIN,CCL18,TMEM107,RPL6,CASP4,WDR44,NPY5R,MIR301A,GNG7,GPR89A,ZNF365,TNFAIP1,MIR214,H2AB1,MIR502,ZBED4,ZHX3,H1-5,IRF4,FUT8,ARF6,TENM3,PDCD1LG2,MDM2,TAC1,HENMT1,MIR583,HTR5A,MIR1-1,HPCA,GNGT2,NRGN,DDX5,NCBP2,ZNF473,ACKR3,CYRIA,CSRNP3,BAG2,TAS2R5,MIR147A,CRBN,ARHGEF39,DLG4,ZNF790,MIR335,ZNF692,TRIM15,CEP70,ZNF326,FAF1,MIR195,HEXB,CDKN1B,MLC1,S100A6,CAMKV,NAA35,MIR218-2,MIR193B,RBM3,SCFD1,CHMP4C,RBM15B,DAAM1,TP53TG5,PLD3,CD209,PARM1,ALB,DPEP1,LRP3,MIR192,DUSP3,MAP2K3,RERE,SESN3,SCAND1,JAGN1,ZNF596,RAB3B,GAS8,PKP4,TMEM182,MIR367,HOXB1,DKK1,SPOCK1,VAMP8,SEMA5A,SRSF7,ADRB2,DDX4,REEP6,PRDM4,GRAP,EIF4EBP2,FKBP1A,CTTNBP2NL,PRPF19,NR1I2,DHX15,IRF8,SAP30L,SYNGR1,SKA3,NUCKS1,CSNK2A1,GHRL,AZIN1,HOXC4,PAEP,PTPN5,ERO1A,S1PR4,RAB3A,RBM23,DCAF5,MVD,BRINP3,IFRD1,DMTF1,FCHSD2,CCL5,RGS19,KCNB1,CDC16,TRIM68,FLCN,ARFIP1,MIR761,MIR484,SOCS2,NUPR1,AGO1,FZR1,HNF1B,MIF,RAB9A,EIF5A2,BCL10,UST,HEY2,PDE7A,ZNF518B,CFL1,OPRM1,C1QL2,SETD7,CPTP,CHID1,CCL27,SPIN3,MIR452,AP2M1,ING2,EFNA5,CYTH1,MDC1,GADD45B,MIR662,IL4,TACR1,FXN,DGCR8,NKRF,SCML1,APBB3,ZSCAN25,MED9,MAGEA4,CYB5D2,UBE2L3,GPAM,FA2H,RHOBTB1,CNOT6L,RASD1,SERTAD1,LAMP3,NLRP1,NPY1R,HILPDA,SYK,FGF16,RAB14,NUF2,EAF2,PRR5L,TESC,OR4K17,FBXW7,PHF23,CLXN,SEMG2,CCL2,CHCHD2,DUSP6,NPSR1,NPPC,TUBB,PDE2A,JMJD8,ARL2BP,ARL6,EIF5B,STX6,RAB5A,G6PD,RARRES2,H2AC1,VPS54,TMEM97,DPP4,FEZ1,MIR32,ZBTB39,MIR632,TBK1,IL17F,TAF10,TAF1D,RASSF4,NTF4,TCIM,ICAM1,THOC1,LYPD6,PHAX,MIR15A,ZFAND2B,RB1CC1,KLF3,CSH1,LAMTOR3,PRDX1,ASB11,CD40LG,STX18,MIR939,MIR140,PDE1B,MTPN,NUDT16,PRELID1,VEGFA,OR9K2,IL23A,CLK1,SAMHD1,FXYD6,MIR944,WDR19,PRKACB,CTNNBL1,KRBOX4,FZD4,CAPN2,AREL1,DEK,NDUFAF4,BICD2,BEX3,BRD9,CIBAR1,SAP30,NFKBIA,ASPA,GPR34,TAX1BP3,PIP4P2,MIR331,GNG3,BAK1,MAP1B,TCAF2,MIR374A,AIFM1,BMP1,FUBP3,TMED4,RPS4X,DUSP26,SERTAD2,GPC1,SLC25A31,RPL26,PHC1,GNB3,CCL28,NRP1,ACP5,USP46,FGF1,MIR450B,CPLX2,SMU1,MIR10B,RGMA,BUB3,TERC,MED13L,PID1,IL2,PAK2,CYTL1,TRIM63,MIR130A,TSC22D3,CAAP1,KIF2A,LAT2,FCAR,LHFPL4,AR,TMEM100,ZNF513,GNRH1,POLD4,MAGEC2,UBE2K,NDST1,ID4,HAPLN2,ZBTB2,ZNF581,CHMP1A,GNAO1,MIEF1,BAHD1,ASPM,PTP4A3,PPP1R12A,MIR1224,CD274,AKT3,GRAP2,E2F4,CLIP3,SNTA1,KLHL25,SMARCE1,RIGI,SMYD3,TXNIP,PEX5L,SIPA1L1,PNPLA8,HP,MIR454,NUS1,INSYN1,HDAC3,SMARCD3,GNG10,IFNK,MIR148A,ZNF24,LCP2,SYT4,SEMA4C,OR8H3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SA,SATB1,ZNF704,TIMP1,PIK3R2,KLF1,SLC6A6,OSM,YWHAZ,CCL1,AMIGO1,MIR301B,STMN2,SOX14,RXFP2,CAMK1,LMBRD2,TNFRSF9,PPP1R11,SPRED1,LPAR6,CLK4,SIRT7,FAM83C,GRPR,SNX18,FBXO9,TCF23,MRGPRX3,VDR,OR10Q1,RGS5,RAB3D,TXNRD1,MIR877,OXTR,ZNF688,MIR345,KICS2,CXCL11,TEF,WNT7A,NPY,VSTM2A,ARFGAP1,CEBPE,TGFB3,SIAH2,OR4E2,DELE1,GNRH2,NYAP2,NCR3,ACO1,FKRP,ITGA2,CCT7,TAF11,PIP5K1A,TCEAL1,PPP3R2,PCSK9,MIR187,RPGRIP1L,B4GALT1,MIR125A,GLCE,PRKCE,DIO2,LCP1,ATF1,PARL,KRT8,PFDN4,INSYN2B,XBP1,CD59,RPL13A,PATE4,MIRLET7B,HIRA,CCND1,PAIP2,MIR492,CNR1,SOD1,LRRTM1,MACIR,MOSMO,MMP14,AHCYL1,EIF4E,TP53INP1,SDC2,PADI2,GADD45G,CETN2,PPP2CB,ACTL6A,DRAM1,FOXP3,CA2,MX1,LMNB1,PAFAH1B2,HAX1,OR13C8,SPRY1,TENT4A,PAX6,TPPP2,GFPT1,WNT10B,MIR577,OR5A2,SAR1B,BABAM1,CDC42EP4,CHMP2B,RPRM,OPTN,CASP12,HHIP,PRKAG1,SLC35C1,MIR887,TP53INP2,UBA3,OR2F1,ATG7,MIR383,OCIAD2,SH2D1A,ZBTB16,DNAJB6,SFN,EHD4,AQP11,NACC2,MIR648,ZNF507,MIR96,NAA15,CRLF3,DDRGK1,MAP3K11,MIR636,MIR611,SLC39A10,CACNB3,PAQR8,CCM2,CX3CR1,CDKN2C,PPP1R1B,RAB11A,ZDHHC8,ABHD17A,BCL7B,HMGB1,MAPRE2,CD1D,MPIG6B,RGS2,SSBP4,CXCR1,CDC42SE2,PTK7,VPS28,CXCR4,OR2H2,BCCIP,HNRNPH3,CD226,PYCARD,LRRC24,OR2W1,TBC1D13,INPPL1,RELL1,TBC1D19,GLRA2,SH3GLB1,HAPSTR1,GUCY1B1,TRA2B,NFE2L1,ADNP,CTTN,VIPR1,CGAS,LMAN1,PRKCA,BRD3,TBC1D5,CD1C,EIF4E2,EDEM2,PIP4K2C,TMEM126A,CDH11,BCL7C,PLSCR1,RRAGA,LPAR1,MRGPRX4,CCNY,MIR133B,CTSC,RRAS2,ARF1,SVBP,AZI2,ITGA6,SCN1B,OR8B12,OR4D2,UBE2D3,PSENEN,PRDX2,TSHR,NKAP,SRSF1,P2RY1,NKIRAS1,CHMP1B,CCL8,EYA3,MIR586,DNAJC2,FSTL1,PTGDS,CUL2,MNAT1,AP1AR,MIR28,OR2Y1,IL34,MIRLET7G,EIF4H,RPS20,EZH2,UPF3B,IL3,ADCK1,MIR554,RABIF,F11R,MIR193A,UFD1,TMEM237,PGR,SLA2,PRKCQ,CLSTN3,PPARG,SRARP,CCDC22,DPY30,PAK1IP1,KRAS,MBD5,IL1A,RIT1,IRF6,TF,ADAMTS1,CEACAM5,GSTM2,ATP6V1G1,FABP7,KLK3,DDIT4,ZNF177,CYTH4,CCL20,IRF7,RER1,SMAD1,MIR425,RETREG3,ACTN4,MIR1260B,LTA,CRHR1,SETD3,IDH1,RNF126,HNRNPC,CLRN1,SUMO1,CDCA7L,TRIM22,AIP,CTNNA2,FEN1,MTF1,ADAMTS20,LITAF,PICALM,PYM1,CASK,PHF13,DLX1,PREPL,RIMS3,MIR126,MIR184,ATP1B3,MIR142,CDC20,DAPK1,APOBEC3D,MIR105-2,OSR2,ATP6AP2,CDK1,OR4K2,DDT,BTF3,NFIL3,EED,CTDSP2,GDI2,MCOLN1,PRDX4,SOCS3,RBBP8,ADGRL3,PPP1CB,MEPCE,MEAF6,MTG1,CDIP1,AGAP2,NDUFA4,CNPY4,OR10G7,ZYX,PIM2,CYP2D6,RBM22,OR10A4,SLC38A3,MIR342,CLDN1,ZNF687,ZHX1,MIR324,UBE2I,APOBEC3F,GPR22,MTM1,TNKS2,PTN,LMBR1L,ALKAL1,CDH8,STC1,CRTC2,SLITRK2,PIK3AP1,MIR920,SERPINB1,TUSC2,OR13A1,CLTRN,TMIGD1,GNB1,MIR23B,RINT1,OTULIN,ANAPC13,CCL23,MACROH2A2,OR4S2,PKNOX1,RPS7,NFKBIL1,STK38,ADIPOR1,TASL,TFCP2,PML,SNAI3,TERT,CRADD,MIR141,IL15RA,GNA11,PABPC1,PLN,DNAJC7,NEK2,CD2AP,UBLCP1,VPS16,FXR2,MARCKSL1,GADD45A,CAMK2N2,H2AZ2,SFTPD,RAB35,CTLA4,JPT2,RNF146,PLCL1,DOK5,MIR7-3,MED17,SERINC3,STK16,FAM162A,SST,MGARP,KCNJ11,MIR765,GNG2,EIF1B,CALY,STAC3,ZNF175,CBLL1,POLR2G,WIF1,MIR601,KRIT1,CD200,DNAJB4,NFE2L2,NCDN,COX17,PRMT6,TCP11L1,MPV17L2,SMARCB1,EFHC1,SLITRK1,TFE3,EI24,MIR549A,DRAP1,UBASH3B,LPXN,SRSF4,MIR625,GTF2IRD1,GSTO1,TRIM3,TAAR1,TOMM7,CCDC3,MIR563,BORCS5,MYT1L,EIF4EBP3,TRNP1,CD164,PACSIN3,CAMK2G,HYAL2,MIR1227,SLC1A1,CTNNB1,CYFIP2,GPT,BRS3,MIR1271,UBE2V1,P2RY4,NDNF,ASZ1,VPS26A,MAPK4,LSM4,SMAD4,SEMA3C,ARHGAP15,ASB3,LMO2,JAK2,PTEN,MORF4L1,FBXL19,MIR500A,LRP6,VLDLR,TTI2,CAND1,LACC1,TMEM215,TEX261,SMCHD1,ABCE1,SLC4A8,LMO4,GRIA1,CDC42EP2,RIOK2,TNFSF13,CREBZF,MIR377,IL22,RLN2,MIR221,ATP5IF1,MIR155,SS18,UBE2M,NUP153,NCOA5,UBE2N,CARTPT,SLC8A1,NPBWR1,THRAP3,LRRC4,RNASEL,LDB2,BRAP,ABHD6,CSK,MIR633,ERP29,CRMP1,BTG1,ZNF267,NCKIPSD,PRL,OTX2,TRPC1,AURKAIP1,LDLR,ZNF263,NEUROD2,GRM1,MIR10A,PPP4C,TRAF7,VEGFC,RXRG,PELI1,PPARA,SNAP91,MED29,PC,TTC23,RBBP9,PMAIP1,BAP1,IREB2,FOXD3,SYN3,HYPK,FERRY3,MIR330,DNM2,CD99L2,CREBL2,TSPAN17,UBE2B,GLIPR2,ELAPOR2,MAEA,SYNCRIP,ANAPC2,ELP6,WDR82,DHRS4,COX7A1,CXCL3,CACNG3,MIR21,FGFBP1,MIR9-2,SHMT1,HMGA1,TWSG1,SPATA4,XCL1,BRMS1L,TRAPPC14,CDK8,SEC13,EDA2R,SLAIN2,LRRTM2,PDIA3,PDE12,RUVBL1,HMG20A,SSU72,DDAH1,ORMDL3,BCKDK,HSH2D,PHACTR1,NSFL1C,TOPBP1,HFE,PFDN5,RAB11B,RHOU,SH3BGRL,ITGB8,OAZ2,EMILIN1,TBC1D24,MZB1,PLG,LURAP1,NDN,DRGX,RBM5,CDK9,GPR83,PHF12,MIR338,PTGER1,GREM2,RNF141,OR52M1,CITED1,PTPMT1,TBC1D10C,MRGPRX1,TYMS,OLFML3,CXCR3,CHST2,CEBPG,PAIP2B,SLC25A27,AIF1,ALDH1A3,LYNX1,MAPKAPK3,MIEN1,TBC1D16,CTSD,KCTD12,SDC4,MIR671,TNFSF10,PPFIA3,ST6GAL1,CIAO1,VCPIP1,STK4,MAP3K3,SYNJ2BP,AVPI1,ZC3H7A,EHD1,ANAPC16,PCGF6,ZNF362,LEPR,NEK7,ZNF574,MGMT,PCGF2,TMEM38B,TRIP4,ITGAV,GHR,LAMB2,LARGE1,BRINP2,TGIF2LX,INPP4A,PIP4P1,ZBED3,HOMER1,KLF4,MPP1,TLR4,APLNR,RPS15,ARF4,C1QTNF1,MIR638,LUM,S100B,TRIM44,APOC2,RBCK1,B2M,RPS26,GTF2I,PRIM2,LHX2,EIF2B2,CD3G,KLHL22,PLGRKT,NQO1,SUFU,CHMP5,TNFAIP8L3,MLF2,PPP2R1A,TNFAIP8L2,NREP,MLF1,MIR212,DSTN,MIR503,SLC16A1,FCMR,F10,SGTA,MIR346,MIR597,NEDD8,DEFB1,LTB,FBLN5,TLE1,MIR30D,COL3A1,OR14J1,SPINT2,MIR517B,CA8,FAM20C,MIR25,FEM1B,RABL3,CCR6,HCFC2,ZNF345,BHLHE40,CST11,MIR1226,CXCL1,PPY,RNF167,TLR7,RASGRP2,RGMB,IL5,EDF1,OS9,KDM1A,MIR511,PPP1CC,MAP3K14,STPG4,TOB2,OR4N4,ANKRD49,IGFBP4,EXOSC4,MIR551B,HCST,ABITRAM,STAT2,CCR5,MCHR2,PDF,OR4K13,CBLN1,ZCCHC7,CHST11,DLG1,SF3B5,SLC25A14,RAB13,ADD2,ZNF821,MIR942,MOSPD1,DEFB124,RAB4A,MIR200A,MAGEH1,RTRAF,CSNK1E,TIMP3,LRRTM3,PPIA,CDC42,CCL3,ATP5F1A,ID1,YWHAH,FRZB,LILRB1,CNTFR,SCG2,MAB21L1,CDNF,BARX2,GTF2F2,IL6ST,BTN2A2,RFX4,SRSF12,MIR661,OR9I1,TYROBP,FASTKD5,DOK4,EEF1E1,MIR876,FURIN,KANSL3,TMEM101,SHC3,MAVS,SSH3,ZBTB17,DEPDC1B,MYORG,RPS9,PLCXD3,CDKN2AIP,STAMBPL1,SEPTIN7,IL20RB,HTRA2,MRLN,BEND6,TAF5L,TRIM54,ZNF436,TULP3,OR5K1,SPTBN1,CD2,NIF3L1,SCYL2,PARP2,KCTD10,TCEA1,XPO1,ASIC1,VMP1,GLUL,STAR,EGLN3,LACRT,YES1,CMTM7,SLC23A2,BIRC2,HR,PTCRA,NPC2,PRKAB1,CH25H,ARFGEF1,TMBIM6,OR4K1,MED10,ACVR1B,SAV1,SGF29,HDAC6,MIR208B,MAGEB1,FOXA3,CCAR2,MED22,TMED9,STK11,CREB3,H2AC25,MRTO4,NHERF1,ZNF805,MAPKAPK5,PIH1D1,DRD1,RDH10,CACNB4,MIR16-1,DCUN1D3,ZNF575,OPRL1,MRPL13,CTNND1,DUSP9,HNRNPDL,OR7D4,MRPL12,CYP1B1,CSNK1A1L,AKAP8L,PICK1,PTHLH,STAT5A,CDC42EP3,PPIF,TIAM1,WDR12,PAFAH1B1,CDC23,STAU1,SESTD1,NEO1,TES,MIR139,CACUL1,PDCD4,ETV6,IL18,PBLD,MIR572,GTF2H2,BZW2,TRIM35,WRAP53,SCHIP1,PMP22,FASLG,PIK3CG,HNRNPA2B1,IL15,MIR137,ABHD2,TLR1,HSPB6,RPS12,ARHGEF6,FABP5,MIR455,SIT1,PPM1G,MIR298,PRRT1,CCAR1,CEP85,LAMTOR2,NF2,RAPGEF5,SSRP1,MIR24-2,NR0B1,SETD4,PIK3R1,CCDC47,MAGED4B,FOXP2,MIR30E,CPLX1,NIBAN2,ISX,STIM1,ASB8,H2AJ,BET1L,MIR493,OR7E24,GARRE1,CCNB1,CRYM,RASGRP3,UCP2,SGMS1,WTAP,ROMO1,DKC1,MIR604,APH1A,SKIC8,MIR639,CALR,GRSF1,ABCB1,MIR675,TTR,GSTP1,TXN,AGTRAP,GH1,RETN,TOX,CCND3,NEUROD6,INPP5E,NPVF,MT3,HERC4,PPP3CA,ITGB5,SLC6A1,MIR182,RANBP1,CLEC1A,ZNF787,AKT1,TLR6,AGR2,EXOSC8,IFNA13,RADX,MTERF2,SLCO3A1,PFKFB2,MIR211,TSG101,KCNS1,PPP5C,TFG,E4F1,NR1H2,ACER3,TMEM88,ZNF343,MIR448,CPE,DLK2,MET,MIR1251,UTS2,TSPAN5,ANP32B,FLRT3,KIT,FAS,TGFBR2,MSH6,PSMG2,UBE2D1,KLRD1,GPM6B,SLC2A8,ERLIN2,KPNA1,FCER1G,SLC7A1,ELF1,CHRM4,MOB3B,EFCAB7,TRAF3IP2,BAX,GP9,PAIP1,MMP9,PYDC2,ACAA2,ATXN10,COPS2,VPS26B,PSMA6,AKT2,ERRFI1,DHPS,FAM89B,MPV17,UHMK1,HMX1,IQSEC1,SF3B4,MIR589,MIR130B,OR2AT4,GPR137,EMC10,SLX1A,GNG5,MIR607,IKZF2,MAD2L2,GMDS,FOXS1,DSTYK,MIR423,ZBTB33,TAPBP,ANXA4,UCN,NCAPG2,CMKLR2,MIR196B,ORMDL1,LEPROTL1,TLR9,METTL18,MIR580,PPP2R5A,SMG8,OCRL,CDKN3,GRIA2,PPP1R10,LPCAT3 |
| 1.072e-04 | -9.14 | HAGH (hydroxyacylglutathione hydrolase) | protein interactions | 3029 | 76 | 37 | 19454 | 5460 |
HSPA8,RAB9A,RAB5A,BAP1,HSPD1,SOD1,SFXN1,PSMA1,ETFA,HSPE1,AURKAIP1,APOBEC3A,RAF1,TOMM22,TP53,BET1,PIH1D1,TFRC,LMNA,PTRH2,BST2,AIFM1,COX4I1,PPIA,SMAD5,DUSP3,PLGRKT,CTSB,MGST3,PYGM,COPS5,CFL2,BAG3,DPP4,RAB11A,UBE2H,S100A11 |
| 1.078e-04 | -9.14 | extrinsic component of plasma membrane | cellular component | GO:0019897 | 100 | 47 | 19108 | 5553 |
GNA11,CTNND1,CDH11,GNAQ,CDH13,JAK1,GNAI2,TOLLIP,TIRAP,GNG13,JUP,GNG3,TRAF6,GNG11,GNB4,MYD88,TIAM1,GNA14,PPP3CA,GNG10,JAK2,GNG12,CDH8,PICALM,CTNNA1,PCSK9,AP2M1,GNG7,GNGT2,TRAF3IP2,GNB1,DLG4,GNB3,CDH7,CTNNA2,STXBP1,SNAP25,GNAZ,IRAK4,GNAO1,GNG5,CTNNB1,SNAP91,GNAI3,CRKL,RNF10,GNG2 |
| 1.079e-04 | -9.13 | GJA1 (gap junction protein alpha 1) | protein interactions | 2697 | 572 | 201 | 19454 | 5460 |
AKT1,RAB2A,GORASP2,DNAJC5,ARHGAP21,SNX5,ATP1A1,NECTIN2,RPS3,PRKCE,SRC,SPTBN1,CDC42,LEMD3,PRKCA,VPS54,GSTP1,TEX264,STK38,NOS1AP,BECN1,CAMLG,RAC2,SLC39A10,FCHO2,SLC38A2,STX6,LMAN1,UBIAD1,PIK3CA,TFRC,EXOC3,ATP2B4,MAP1B,PALM2AKAP2,SLC6A8,SLC30A5,LAMTOR1,CKB,CCT2,GCC1,SLC38A1,LMBR1L,FAM83B,PRMT5,ATP5F1B,PSMD4,BET1,USP6NL,TMEM115,EIF4B,RAB5A,HSPA8,UFL1,TSPAN10,PLPP4,RAB5C,LAMP2,DDRGK1,CTNNB1,PPFIBP1,RAB35,TNIK,PCDH9,STX5,RHOH,ARFGEF1,STBD1,PCDH19,TMEM59,SOX2,DNAJC25,HGS,TMEM87A,EFNB1,ROCK2,KRAS,EPHA4,FLRT3,CSK,CREB3,DEPDC1B,ATP5F1A,ARFGAP3,LRP6,EPHA2,GAB1,VAMP3,YES1,RHOJ,FERMT2,SH3BP4,CLRN2,PIP5K1A,ARHGAP1,SEC22B,CCN3,UBA52,RABL3,ATG16L1,SLC12A2,PICALM,GOLGA5,STOM,JUP,LMNA,STAMBP,MET,RHOU,PPM1G,SQSTM1,PRKCB,PIK3R2,USP8,RPL4,YKT6,NF2,GTF2I,TMEM209,GABARAP,TMEM199,MICB,RELL1,RAB23,LAMP3,TIAM1,ESYT1,OSBPL8,UPK1A,EHBP1,ACTA2,SRPRA,PTPN1,CDCA3,HSD17B11,CGAS,PRNP,ARF6,COG1,CAV1,SLC25A12,CCDC47,CD2BP2,EEF1A1,MAP1LC3B,ZDHHC8,CASK,DLG1,NSDHL,SHISA2,IGF1R,SNAP23,TSPAN17,SEPTIN7,CTNND1,GPR17,PKP4,VEZT,NIBAN2,MYO6,YWHAZ,RHOB,LMNB1,SCFD1,DPEP1,ARF1,LRRC1,MB21D2,B4GAT1,NOTCH2,GJC1,WDR77,STXBP1,RND2,VAPB,ARCN1,STX7,PIK3R1,PPM1B,RHOG,CDK5RAP3,WDR6,GJA1,TSG101,SPTAN1,OCRL,MACO1,TULP3,FAF2,RPN1,VAMP2,STIM1,PLD3,STX12,DEFB124,TMT1A,AKT2,SCYL2,TAS1R2,SEMA4C,UBE2A |
| 1.080e-04 | -9.13 | MED8 (mediator complex subunit 8) | protein interactions | 112950 | 117 | 52 | 19454 | 5460 |
POLR2B,MED17,POLR2F,CPSF1,PNMA1,RIT1,SNTA1,MED10,STN1,ATG3,AR,LMO2,MYC,CUL2,MED22,CXXC1,MED11,FBXW7,MED13L,FOS,PML,PHYHIP,MED31,MED23,MED30,FBXL19,CCL3,ACTL6A,ATG16L1,POLR2I,BRD9,POLR2L,MED4,MED27,MED21,MED29,ELOC,GAPDH,MOV10,ZCCHC10,INO80E,KRAS,EWSR1,TRIP4,POLR2G,POLR2C,POLR2D,BIRC5,CDK8,RPAP2,TP53,MED9 |
| 1.087e-04 | -9.13 | U4 snRNP | cellular component | GO:0005687 | 10 | 9 | 19108 | 5553 |
SNRPE,SNRPN,SNRPG,SNRPB,SNRPD3,PRPF31,SNRPD1,DDX39B,SNRPD2 |
| 1.097e-04 | -9.12 | RAP1A (RAP1A, member of RAS oncogene family) | protein interactions | 5906 | 154 | 65 | 19454 | 5460 |
HSPA5,STX7,TACR3,SOD1,DUSP9,RAB5A,PMAIP1,AKAP1,RABAC1,MRPL34,SYVN1,FGFR1,CPLX2,CAV2,BORCS8,DUSP22,GABARAPL2,RGL1,CDC42,TAX1BP1,MGST3,RAPGEF5,PARL,ESR2,VIRMA,RABIF,GNB1,DLST,GNG12,UQCRC2,GANAB,RHOB,FAS,UBE2H,OSGEP,DNAJC8,AR,RHEB,KRAS,HNRNPDL,RAB8B,DUSP19,IMMP2L,RAB1A,FAF1,CACUL1,CHMP4C,KRIT1,TMEM31,PDE6D,IFT22,RAP1A,CENPM,RAF1,KBTBD4,FEN1,PPP2R1A,RPL35A,HNRNPL,POLE3,RASGRP2,RAB35,HNRNPD,RAB5C,LAMP2 |
| 1.104e-04 | -9.11 | ribonucleoside triphosphate biosynthetic process | biological process | GO:0009201 | 91 | 44 | 18204 | 5365 |
COX11,ATP5MK,NDUFA12,NME2,NDUFA5,NDUFB7,ATP5MC3,UCK2,NDUFA1,NDUFS8,ATP5F1A,NDUFB10,NME1,NDUFAB1,NDUFB6,ATP5F1B,NDUFV2,NUDT2,ATP5PD,ATP5PB,UQCC3,DNAJC30,STOML2,UCKL1,NDUFS2,ATP5MG,ATP5PO,SDHB,LIPA,NDUFA2,NDUFB8,SDHC,NDUFS6,NDUFC2,ATP5PF,NDUFB5,ATP5MC1,ATP5F1D,NME4,ATP5F1E,NDUFS3,ATP6V1A,NDUFB4,UCK1 |
| 1.105e-04 | -9.11 | TMEM72 (transmembrane protein 72) | protein interactions | 643236 | 38 | 22 | 19454 | 5460 |
SLC35A5,SYNJ2BP,PEX3,GGCX,ATP1A3,FXYD6,ENDOD1,SFXN2,SLC1A1,TMEM237,PIGY,MGST3,YIPF5,TUBA1A,KDELR2,CAV2,DHRS7B,SURF4,SAMM50,SIGMAR1,LPCAT3,RER1 |
| 1.106e-04 | -9.11 | PIK3R6 (phosphoinositide-3-kinase regulatory subunit 6) | protein interactions | 146850 | 12 | 10 | 19454 | 5460 |
RPL10A,H1-1,TCP1,S100A10,DHX9,HSPA8,PIK3CG,RFC5,ASRGL1,STUB1 |
| 1.106e-04 | -9.11 | EPG5 (ectopic P-granules 5 autophagy tethering factor) | protein interactions | 57724 | 12 | 10 | 19454 | 5460 |
MAP1LC3A,CREBBP,TP53,EDEM1,ZDHHC15,VIRMA,APEX1,RIGI,AGR2,USP8 |
| 1.106e-04 | -9.11 | SHISA5 (shisa family member 5) | protein interactions | 51246 | 12 | 10 | 19454 | 5460 |
COPS5,SGTA,TOP3B,ALG2,TP53,HNRNPD,RIGI,TVP23B,DESI1,SCAND1 |
| 1.107e-04 | -9.11 | USP7 (ubiquitin specific peptidase 7) | protein interactions | 7874 | 791 | 269 | 19454 | 5460 |
WTAP,SHOC2,RPLP0,LEPR,METTL14,PAK5,LMNA,KLF12,TPT1,UBA52,SAP30BP,HMGB1,GTF2I,FLCN,SYVN1,SIRT7,DVL2,PPM1G,RPA3,XPOT,SMAD2,PIP4K2C,AR,IFNAR1,USP14,GMPS,PPP1CC,RPL26,CSK,PNPLA4,VIRMA,SCML2,UBB,NR1H2,ALB,PTEN,TRIM27,CTTN,PELP1,STUB1,CCNF,MAP2K3,ING1,FBP1,MDC1,ARF4,THRAP3,BACH1,TRIM63,NSMCE3,HUWE1,SEM1,PC,ZC3H11A,HAPSTR1,RING1,NKRF,PPP1R12A,ID1,MPG,SUV39H1,HDAC6,ERCC3,CAV1,MDM2,CGAS,RB1,ETV6,SMAD3,PCLAF,ABCB1,PPARG,PGRMC1,BEND5,ALKBH3,SKP1,G3BP2,RNF11,COIL,SLC15A1,MCMBP,TERT,PSMA3,NMRAL1,CRY1,BIRC2,TXNL1,HTRA2,RIT1,SP1,LMNB1,DCAF4,BRCA1,MCM3,MCM4,PKP4,CUL3,ALDH1L1,TNPO3,RBBP4,UMPS,SNRPD1,FOXP3,UBE2S,RNF126,RBPJ,VAMP2,EZH2,NFE2L1,TULP3,ASPM,PPP2R1A,E2F4,GIN1,RAF1,PCGF6,MCM6,SRSF4,PCGF3,DICER1,TRAF6,ZNF207,BABAM1,MARCHF5,TRIM8,PRPF19,HMGA1,DHX15,EGLN3,SPTAN1,TRIM35,GJA1,PSMB5,PSMB4,THOC2,LUC7L3,KLF4,TFIP11,DDX4,WRAP53,RPA2,IPCEF1,NEK2,SPTBN1,BCL6,KDM1A,PML,NBN,ARHGEF6,BAP1,UBE2H,ZBTB38,IGF2BP1,UBE2E3,ST13,RPL7A,SMARCA5,RSPH1,DYRK1A,SRC,TRAF1,BUB3,TRIM54,PITPNB,UBN1,CREB1,RPS3,NUPR1,SH3GLB1,DISC1,CDK8,H2AX,SP4,TP53,KBTBD4,RBCK1,PSMA5,H3C1,DHX9,ABCE1,NAE1,MYD88,USP15,ATP6V1D,KPNA1,SHC1,BECN1,H2AC4,SNRNP70,SMAD4,COPS5,CSNK2A1,PPIL4,PLEKHO1,CDC5L,TMPO,NKAP,GRM1,FZR1,CDR2L,EEF1B2,CD274,PIH1D1,KLC2,EIF4B,TANK,EEF1G,STAU1,UBE2D3,TRIM22,DDX5,AKAP1,PCGF2,YAF2,EP300,HDAC5,SF3B1,THTPA,PHF7,HNRNPC,SFN,MYC,CREBBP,ESR2,PSMB6,FBXO22,HECW1,TCEAL1,MATR3,PSMD4,DLST,MOB3C,CRKL,KIF2A,SPG21,SOX2,TRAF2,TOP3B,PAK6,CCAR1,DCTPP1,RPS4X,FOXN2,ZNF609,KRAS,PSMA2,HNRNPF,TRIM11,EWSR1,PICK1,RUVBL2,MYO1B,TOP2B,PABPC1,TMEM87A,POU5F1,AGR2,DDRGK1,CTNNB1,F7,WWP2,DDX50,IFI16,OSBP,SUMO2,MEAF6,HNRNPL,MAGED2,EED |
| 1.108e-04 | -9.11 | unfolded protein binding | molecular function | GO:0051082 | 116 | 54 | 18094 | 5411 |
DNAJC4,CDC37L1,DNAJB6,CLU,TUBB4B,HSP90AA1,PFDN4,CALR,CCT7,CCAR2,SRSF10,SYVN1,TAPBP,RUVBL2,SRSF12,LMAN1,GRPEL2,DNAJB2,HSPB6,RP2,HSP90AB1,HSPB1,GRPEL1,TOMM20,SERPINH1,PFDN6,PFDN5,CCT2,PTGES3,CRYAB,PDRG1,AIPL1,HTRA2,TTC1,SCG5,HSPA5,ERLEC1,MKKS,CLPX,HSP90B1,CCT8,DNAJB4,PPIB,PFDN1,PFDN2,NUDCD3,HSPA8,HSPD1,HSPB2,HSPE1,CCT5,TCP1,AIP,PPIA |
| 1.108e-04 | -9.11 | PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G) | protein interactions | 5496 | 300 | 114 | 19454 | 5460 |
PSMA1,PTPN4,AHCYL1,SAR1B,PPAN,RPL31,RPS24,EWSR1,H2BC1,STMN2,E2F4,ZNF263,B3GNT2,TULP3,DNAJC25,KCTD10,TTC9C,PAIP1,HMG20A,EGLN3,DIRAS3,PTK7,COPS2,ARHGAP25,GJA1,WDR12,RSBN1L,MED4,AHSA1,MAP1S,WWP2,IFI16,DNTTIP1,ARHGEF39,MRPS7,XRCC5,TTC1,HADHA,EP300,NUP50,HSPA8,ARCN1,PIH1D1,LRIF1,LMBR1L,SRXN1,FAS,VMP1,DNAJB6,PFDN4,CUL3,MYC,THRAP3,KPNA2,H3C1,RNASEL,SOCS2,MEPCE,TCOF1,MAP1B,FAF1,RAB27A,ABCE1,SIX5,CDK8,CBX3,APEH,IPO8,H2AJ,WBP11,H2AX,FZR1,DNAJC1,CAND1,CAV1,H2AZ1,SRP14,CD274,ARL4D,H2AC4,TCEANC2,UGP2,SIRT7,BAP1,RPA3,H2BC12,RNF113A,H2BC11,LMNA,RPA2,STAT6,MACROH2A2,UBE2M,HEXIM1,SPR,PSMC4,SNX3,COPE,DYRK1A,TFEB,SRPK2,VIRMA,ZNF330,OPTN,CCNF,PTEN,SYT2,SNX12,DNAJC19,UBE2H,CARS1,KPNA6,GMPS,DNAJC8 |
| 1.117e-04 | -9.10 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 35 | 21 | 16828 | 4835 |
FBXW7,ETV6,JAK2,AKT1,TP53,KIT,RB1,CTNNB1,EZH2,PTEN,TERT,PIK3CA,IDH1,HRAS,KRAS,SMAD4,NFE2L2,SF3B1,EWSR1,SS18,STK11 |
| 1.117e-04 | -9.10 | RBM12B (RNA binding motif protein 12B) | protein interactions | 389677 | 63 | 32 | 19454 | 5460 |
SQSTM1,HNRNPH2,MIRLET7C,RNF20,G3BP1,B9D2,PPP1CB,SF3A1,NUPR1,EIF4B,CHMP4C,HDAC11,MIRLET7B,EED,NUP35,ESR2,EGLN3,MIRLET7D,SRSF10,SNRNP40,MIRLET7G,MATR3,PPP1CC,HNRNPA1,RNF40,MIR98,MYC,MIR34A,USP15,MIR363,MIR31,DCAF4 |
| 1.117e-04 | -9.10 | TMED1 (transmembrane p24 trafficking protein 1) | protein interactions | 11018 | 63 | 32 | 19454 | 5460 |
EXOC3,NFKBIL1,KLRD1,JUN,E2F4,TP53,FGF17,JPH4,UBL4A,RAF1,RNF26,PDE2A,SGF29,HSCB,RNF5,FGF3,KLK5,SAYSD1,SHC1,CD226,CDK5RAP3,DDRGK1,EXOC1,GORASP2,BFAR,CREB3,GPR37,EGLN3,DUOXA2,TMED9,SMAD3,S1PR4 |
| 1.117e-04 | -9.10 | GP5 (glycoprotein V platelet) | protein interactions | 2814 | 63 | 32 | 19454 | 5460 |
MGST3,ARL6IP5,DERL2,CNPY4,VKORC1L1,MSMO1,ARL10,SLC39A10,ADGRL3,STARD3NL,ATP1A3,ATP5MC1,YWHAZ,TMEM70,F2,TOMM40,RHOBTB3,LRRC40,HMOX2,FAM241A,CNNM4,CMTM6,ATP2C1,HSPD1,RAB29,RTN4,UBAC2,GHITM,TOMM22,SLC19A2,CNPY3,YIPF5 |
| 1.119e-04 | -9.10 | viral life cycle | biological process | GO:0019058 | 178 | 76 | 18204 | 5365 |
SLC20A2,LAMP3,CD86,PPIA,TRIM62,VPS4A,CHMP1A,PHB1,CLDN9,TFRC,AVPR1B,HYAL2,ICAM1,WWP2,SLC7A1,RPSA,CD209,GPR15,NECTIN2,RNASEK,ITGA2,VPS4B,CXCR4,VPS28,CLDN6,EPHA2,RAB1B,VAMP8,CHMP1B,LDLR,DAG1,HTR2A,USP6NL,CDK1,PPID,ITGAV,CXCR6,ITGB5,MOG,KPNA6,VPS18,SPCS1,RAB1A,CD80,CHMP2B,HSP90AB1,MRC1,CTBP1,SMARCB1,CAV2,NRP1,CTSB,FURIN,PC,TNFRSF14,CHMP2A,CCL2,KPNA2,TSG101,CAV1,PLSCR1,CD4,CD81,JPT2,DPP4,DEK,CD46,NUP153,IDE,CLDN1,CHMP4C,CCR5,WWP1,CHMP5,SIVA1,F11R |
| 1.120e-04 | -9.10 | FAM98B (family with sequence similarity 98 member B) | protein interactions | 283742 | 106 | 48 | 19454 | 5460 |
UFL1,FBXW7,MIR7-3,PAFAH1B2,MIR106A,RPA3,BAP1,MIR10B,MIR205,MAPKAPK3,HSPA8,RPA2,ZNF574,ATG16L1,PPP1R8,EHD1,EIF4H,TRIM29,IDE,CCNF,MIR16-1,RTRAF,SPOP,UBE2H,MYC,CUL3,GORASP2,RPL28,BCKDK,RTCB,ACTR2,RAF1,EEF1A1,MIR222,MIR200C,CAND1,MIRLET7G,MIR9-1,PHB1,MIR141,DDX1,MIR34A,MOV10,HNRNPA1,COPS5,XPO1,CD81,DDRGK1 |
| 1.120e-04 | -9.10 | USP6NL (USP6 N-terminal like) | protein interactions | 9712 | 106 | 48 | 19454 | 5460 |
RHOU,RAB5A,STX7,H1-5,DUSP14,RND2,CDC42,CCNA2,FGFR1,UBE2S,RHOJ,VIRMA,CSK,SFN,EPS8,ANAPC15,DNAJC5,LAMTOR1,RHOB,YWHAZ,EPHA2,NTRK3,NTRK2,FAM168A,KRAS,EPHA4,FLOT1,ACTN4,RND3,NUPR1,HRAS,RAB35,COMT,GJA1,RAC2,ARF6,RHOH,EPHB6,DIRAS3,CAV1,ATG9A,WWP2,YWHAH,YWHAG,CTNNB1,RHOG,YWHAB,STYK1 |
| 1.121e-04 | -9.10 | PCK2 (phosphoenolpyruvate carboxykinase 2, mitochondrial) | protein interactions | 5106 | 95 | 44 | 19454 | 5460 |
PRKCE,UBE2L3,LMBR1L,ZMYM2,LACRT,SPOP,COP1,MYC,GMPS,NONO,FBXW7,HSCB,EMC1,TOMM20,NT5C3A,EP300,PAFAH1B1,PGRMC1,SUFU,PRNP,CWC15,NUP35,PPIA,PRCC,AIFM1,SMAD3,GATD3,TES,TSG101,GSTO1,HSPE1,CBLL1,IMMP2L,HSPD1,EMC2,HAPSTR1,NDUFS6,PDHA1,BPIFB1,RAF1,RBM12,ZMYM3,ZMYM4,CCS |
| 1.126e-04 | -9.09 | soft_tissue-nerve_sheath-schwannoma | COSMIC cancer mutations | soft_tissue-nerve_sheath-schwannoma | 26 | 17 | 16828 | 4835 |
IDH2,NF2,AKT1,ETV6,CTNNB1,KIT,PTEN,SMARCB1,PIK3CA,TERT,IDH1,KLF4,KRAS,HRAS,EWSR1,GNAQ,STK11 |
| 1.127e-04 | -9.09 | PLXNB2 (plexin B2) | protein interactions | 23654 | 157 | 66 | 19454 | 5460 |
RHOB,NIF3L1,SDF2L1,NTRK3,CUL3,RAB2A,GGH,HMOX2,SPCS1,RHOJ,LYPD6,APEX1,VIRMA,LMBR1L,VDAC2,SEC61B,DNASE1L1,SSR1,EDDM3B,ST7,SEC62,TSHR,CDC42,RND2,TMEM106A,OTULINL,CLEC12B,ST8SIA4,PTN,TMEM106B,RHOU,RAB9A,DERL1,CST11,HSPA8,RHOG,SMAD4,RAB5C,DPP4,LAMP2,SCGB1D1,LAMP3,RHOH,ARF6,DNAJC1,TLR1,RAB35,RAC2,HSD17B11,ADAM21,SFTPC,RPN1,RND3,YTHDF2,TOP3B,CBLN4,CLEC2B,DNAJC25,SEMA4C,KRAS,SIAE,FKBP8,PFDN1,TMT1A,CYP2C9,IGF1R |
| 1.130e-04 | -9.09 | regulation of T cell activation | biological process | GO:0050863 | 384 | 147 | 18204 | 5365 |
CSK,IL21,IL6,CD86,CCL5,CD47,PIK3CA,SDC4,ACTL6B,IFNG,SLC7A1,IL12B,SOS2,IDO1,PTPN11,FGL2,IL6ST,PRNP,BTN2A2,CD40LG,LEP,KLHL25,THY1,SMARCE1,PELI1,TNFSF8,CD83,RAC2,PNP,IL18,PRDX2,ACTL6A,SASH3,NKAP,JUNB,LILRB1,DHPS,IL12A,FOXP3,SRC,CD274,BCL10,HSPD1,CD28,B2M,CBFB,CD80,IL23A,DROSHA,IL7,CAV1,IFNB1,IL15,EPO,LGALS3,RC3H2,SMARCB1,WNT10B,PRELID1,MIR181C,SIT1,CD46,LILRB4,CD81,TNFRSF9,MIR21,IFNA2,CD4,MIR30B,IL20RB,SOCS5,RUNX1,SMARCD3,TNFRSF1B,IL4,IRF1,TNFAIP8L2,GPNMB,ZBTB16,PRKCQ,TESPA1,GPAM,CTNNB1,NCK1,RPS3,SELENOK,TFRC,YES1,TOX,IL2RG,VSIR,CD209,ACTB,EP300,IGF1,CD2,TWSG1,XCL1,DUSP22,IL10,IL1A,DUSP3,CCR7,DUSP10,BATF,PYCARD,TNFSF18,AGER,PPP3CA,PTPN22,HMGB1,SYK,CD1D,IL1B,HFE,AKT1,BCL6,RAG1,ARG2,BAD,CGAS,CCL2,JAK2,TNFRSF14,IL2RA,ICOS,PLA2G5,CCR2,IL2,TGFBR2,IRF4,SFTPD,AIF1,CCL19,EFNB1,DPP4,DLG1,RHOH,CTLA4,PDCD1LG2,CYRIB,SOD1,CCL21,XBP1,NDFIP1,NLRP3,TRAF6 |
| 1.130e-04 | -9.09 | regulation of leukocyte cell-cell adhesion | biological process | GO:1903037 | 384 | 147 | 18204 | 5365 |
CXCL12,AKT1,BCL6,HFE,IL1B,SYK,CD1D,HMGB1,PTPN22,PPP3CA,AGER,ADTRP,PYCARD,DUSP10,CCR7,IL1A,DUSP3,DUSP22,IL10,XCL1,IGF1,TWSG1,ACTB,EP300,TNF,CD209,VSIR,IL2RG,YES1,TFRC,SELENOK,RPS3,NCK1,GPAM,TESPA1,TRAF6,CCL25,NLRP3,MIR222,NDFIP1,CHST2,XBP1,CCL21,CYRIB,PDCD1LG2,RHOH,CTLA4,DLG1,DPP4,CCL19,AIF1,EFNB1,SFTPD,MIR221,TGFBR2,CCR2,IL2,MIR125A,PLA2G5,CCL28,ICOS,IL2RA,TNFRSF14,JAK2,CCL2,BAD,ARG2,FUT9,MIR141,RAG1,HSPD1,BCL10,CD274,SRC,FOXP3,IL12A,DHPS,LILRB1,SASH3,ACTL6A,NKAP,PNP,PRDX2,IL18,CD83,PPARA,PELI1,THY1,SMARCE1,KLHL25,LEP,CD40LG,KLF4,BTN2A2,ST3GAL4,IL6ST,PRNP,FGL2,PTPN11,IDO1,IL12B,SLC7A1,IFNG,ACTL6B,PIK3CA,CD47,SDC4,CCL5,CD86,IL6,IL21,CSK,ZBTB16,PRKCQ,GPNMB,TNFAIP8L2,IRF1,IL4,MIR31,SMARCD3,RUNX1,SOCS5,IL20RB,MIR30B,CD4,MIR21,IFNA2,MIR146A,CD81,LILRB4,CD46,MIR181C,WNT10B,RC3H2,SMARCB1,LGALS3,EPO,IFNB1,IL15,CAV1,IL7,IL23A,CBFB,CD80,MIRLET7G,B2M,CD28 |
| 1.132e-04 | -9.09 | PF4 (platelet factor 4) | protein interactions | 5196 | 31 | 19 | 19454 | 5460 |
CXCL8,CCL11,CCL5,CCL28,SRGN,CCL20,XCL1,CXCL12,CCL21,SDC2,CCL25,LDLR,CXCL14,CXCR3,CXCL10,CXCL11,THBD,CXCL9,CCL2 |
| 1.132e-04 | -9.09 | CACNG6 (calcium voltage-gated channel auxiliary subunit gamma 6) | protein interactions | 59285 | 31 | 19 | 19454 | 5460 |
RNF121,PIGW,FITM2,TSPAN3,VMP1,LMBRD2,GOLGA5,NRM,SLC19A2,SLC25A14,MSMO1,TNPO3,SLC38A3,LGALS3,MFSD5,RABAC1,SLC35F2,HSPD1,CD63 |
| 1.138e-04 | -9.08 | Mitotic Anaphase | REACTOME pathways | R-HSA-68882 | 179 | 80 | 10285 | 3229 |
PSMA1,PSMC3,SKA2,PSMD4,MIS12,LMNB1,ANAPC11,PPP1CC,RPS27A,PSMD6,ANAPC2,ANAPC15,PSMB4,CDC23,CENPM,UBE2D1,PSME2,PTTG1,ANAPC4,CENPL,PSMB9,MIR484,NUF2,SEM1,KIF2A,CENPP,PPP2CB,NUP107,MAD2L1,XPO1,PSMA6,PSMD1,PSMB2,MAPRE1,B9D2,NUP37,PSMD12,PSMC1,NDC80,ANAPC16,SEC13,RAD21,PSMD14,UBB,VRK1,PPP2R1A,CDC26,UBA52,LMNA,PSME1,DSN1,PSMD10,PSMD7,PAFAH1B1,PSMB11,PSMC5,PSMB10,PSMA5,BANF1,SPC24,PSMA4,PSMB3,PSMA2,PSMB6,TMPO,PPP2R5E,BUB3,CDC20,PSMB1,NDE1,SKA1,CDC16,PSMD3,PSMB7,PSMC4,PPP2R5A,PSMB5,PSMA3,BIRC5,LEMD3 |
| 1.139e-04 | -9.08 | LIMD1 (LIM domain containing 1) | protein interactions | 8994 | 120 | 53 | 19454 | 5460 |
BAG2,ZYX,TULP3,UBR7,PPP2R1A,TNRC6C,KBTBD4,DISC1,VPS33A,KRT8,IGBP1,DSTN,ETV6,EGLN3,CNTROB,ZNF576,SPPL3,TRIM35,HNRNPL,CTNNB1,YWHAH,XPO1,YWHAG,SSX2IP,TRAF6,SQSTM1,PHYHIP,RPA3,RPP14,EIF4E,PYGB,STAU1,PPP2R3A,EHD1,GTF3C4,LPXN,RPA2,GSK3A,PHAX,CTNNA1,CDPF1,CCNF,ESR2,EGLN2,ACTB,RHOBTB3,CUL3,LMO2,UBE2H,PFDN2,NTRK3,TEX19,BICD2 |
| 1.139e-04 | -9.08 | BRCC3 (BRCA1/BRCA2-containing complex subunit 3) | protein interactions | 79184 | 120 | 53 | 19454 | 5460 |
EGLN3,SUMO2,CAND1,CBL,SHC1,CRBN,UBE2D1,CTNNB1,YWHAH,YWHAG,COPS5,WWP2,BABAM1,FANCG,MDC1,MSH6,RNF20,BACH1,HUWE1,CDK5,FAF1,TFPT,MTA2,DNAJC25,TRAF2,TP53,SNAPC5,RAF1,ESR2,JUNB,STUB1,NLRP3,UBE2H,EXOC8,STK11,BRCA1,PPP1CC,DRAP1,IFNAR1,BRAP,FBXO7,RNF40,CUL3,NUCKS1,DNAL4,GPHN,PML,RPA3,WWP1,RPA2,ATP5PO,CD2AP,SF3A1 |
| 1.147e-04 | -9.07 | RNF181 (ring finger protein 181) | protein interactions | 51255 | 137 | 59 | 19454 | 5460 |
ALB,TRIM24,UBB,BUB3,FBXO7,BTF3,NDUFB10,PSMB2,RPL7A,ICA1,UBE2E3,BIRC2,DCTN3,SLC32A1,MT2A,TSR3,UBE2D3,PHB2,MTMR6,TPT1,PSMB3,ARCN1,MYL6,ATP5PO,DCTN4,ZNF326,HSP90B1,CLK4,UBE2N,PEG10,RPL35A,TOP1,TCP1,ADCY2,ATG7,TPM3,PSMD3,KARS1,ADIPOR2,TRIM8,BCL10,UBE2D1,HBA1,PICK1,ACTR1B,RTCB,RPS27A,SEM1,MT1E,RBCK1,CSE1L,ACTR1A,PSMB9,H1-3,NPY5R,BTG1,GNB1L,SNRPE,RNF181 |
| 1.147e-04 | -9.07 | Bmpr1a (bone morphogenetic protein receptor, type 1A) | protein interactions | 12166 | 137 | 59 | 19454 | 5460 |
YES1,CTNNA1,GNG12,STUB1,BST2,CHCHD6,RMDN3,ATP1A1,HSP90AA1,RNF40,ATP5F1A,ARL6IP6,ATAD1,RNF5,GOSR1,PACSIN3,CHMP2B,LRP10,BMPR1A,SNCG,RAB9A,SLC12A2,STOM,HSP90B1,JUP,VAPB,NOTCH2,RABL3,UQCRC1,CAV1,TMEM237,HSP90AB1,ERLIN1,SLC38A2,PPIA,PHB1,NDUFB4,ATP6V1A,SLC39A10,SLC2A1,HSPB1,HAX1,STOML2,WWP2,GAPDH,SRPRB,FKBP8,FLOT1,FASTKD5,RAB1A,LTBR,CYBRD1,SLC16A1,JAK1,TFRC,NDUFA12,ETFB,ERLIN2,FAF2 |
| 1.149e-04 | -9.07 | positive regulation of T cell activation | biological process | GO:0050870 | 255 | 103 | 18204 | 5365 |
IL2RG,YES1,TFRC,SELENOK,NCK1,RPS3,GPAM,TESPA1,XCL1,IL1A,CD209,VSIR,IGF1,ACTB,EP300,DUSP10,AGER,PYCARD,CCR7,IL1B,AKT1,BCL6,PPP3CA,CD1D,SYK,HMGB1,BAD,RAG1,JAK2,CCL2,ICOS,IL2RA,TNFRSF14,RHOH,CYRIB,PDCD1LG2,CCL19,EFNB1,AIF1,TGFBR2,CCR2,IL2,DPP4,TRAF6,NLRP3,CCL21,XBP1,CD86,IL6,IL21,CSK,IL12B,SLC7A1,IFNG,PIK3CA,CD47,CCL5,ACTL6B,KLHL25,LEP,CD40LG,SMARCE1,THY1,PTPN11,BTN2A2,IL6ST,DHPS,LILRB1,HSPD1,BCL10,CD274,IL12A,SRC,FOXP3,IL18,PNP,CD83,SASH3,ACTL6A,NKAP,IL7,CBFB,CD80,B2M,CD28,IL23A,WNT10B,SMARCB1,EPO,IL15,CAV1,CD81,LILRB4,MIR30B,MIR21,CD4,CD46,IL4,ZBTB16,PRKCQ,RUNX1,SOCS5,SMARCD3 |
| 1.152e-04 | -9.07 | PPARG (peroxisome proliferator activated receptor gamma) | protein interactions | 5468 | 285 | 109 | 19454 | 5460 |
NFKBIB,GADD45G,LRIF1,LGALS3,PROX1,CREBBP,SP1,HSP90AA1,SERPINH1,GADD45B,HSPA8,EP300,SMARCD3,XRCC5,FLYWCH2,PSMC1,ZBTB5,PHB2,LMO4,ATP5PO,PPARG,MAP2K1,RFX5,BRD9,FABP5,RPL9,RXRG,SRSF1,NOP58,TCP1,YWHAG,XPO1,CTNNB1,HMGA1,YWHAB,IKBKB,PPM1B,CDK5,RUVBL2,BAG2,TRIP4,TOP2B,CCT8,RPS4X,TRIM37,RUVBL1,JUN,MSX2,ANP32A,VDR,TRIM27,MACROH2A1,UBE2I,TRIM24,MSN,STUB1,RPS3,LIG3,SH3BGRL,STAT5A,NR1H2,TUFM,SMARCA5,RPL7A,POU1F1,ZNHIT3,TADA3,NR0B1,ARPC2,LCP1,NBN,PML,SIRT7,PIAS1,FABP4,HSPA5,GTF2I,HDAC3,PRMT2,IGFBP3,EDF1,ZSCAN1,PAQR3,PRKCA,PDIA2,KLF4,STAT6,RPA2,RB1,SMAD3,MDM2,CAV1,COPS5,MPG,NFKB1,SELENOS,PGAM1,DNAJC7,RPL10A,NR4A2,DHX9,RIGI,HNRNPK,TRIM63,MLLT6,SELENOK,TP53,ILF2,NFE2L2 |
| 1.153e-04 | -9.07 | NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2) | protein interactions | 4695 | 198 | 80 | 19454 | 5460 |
CCDC90B,MTG1,WNT10B,LMBR1L,TACO1,UBE2I,PSMD6,SNX3,LAMTOR3,ATP5F1B,PARL,UQCRQ,CUL3,PMPCA,MRM2,SUGP1,NDUFB7,AUH,MTG2,MYC,NDUFB10,TUFM,TOMM40,BTF3,RBM27,ATP1B3,CISD1,HTRA2,RIT1,DNAJC19,EXD2,PML,NGRN,GFM1,EMP3,NDUFC2,PHB2,HSCB,ABCC2,ARMCX2,SPR,PCLAF,MTRES1,COX4I1,SDHB,SSBP1,FAHD1,GATD3,NDUFA1,RFX5,NUP35,COX14,MTRF1,GRSF1,ATP1B1,NDUFV2,CHCHD1,TMEM70,RHOG,SKIC8,MRPS26,NDUFA4,HSPD1,ZC3H11A,HINT2,DNAJC30,TRMO,IMMP2L,FASTKD5,OLA1,MRPL11,NDUFA2,MTCH2,UBL4A,METTL15,AURKAIP1,NDUFS3,NDUFS6,GFM2,NDUFA12 |
| 1.163e-04 | -9.06 | FGFR1 (fibroblast growth factor receptor 1) | protein interactions | 2260 | 611 | 213 | 19454 | 5460 |
STX18,MLC1,RUSF1,PALM2AKAP2,ATP2B4,MRPS33,TGFBR2,L1CAM,FGF23,SNAP29,RAP1A,TSPAN3,IL20RB,GOLGA7B,TFRC,SFTPC,NHERF1,AGER,TRAPPC3,MRPS9,ITK,TMED9,FCHO2,KARS1,SHC1,RAB9A,SEPTIN6,APMAP,ITM2B,CLU,LITAF,GREM2,NTPCR,HEXIM1,AVPR1B,LEMD3,FGFR1,EIF2S2,SLC1A1,EPCAM,CDC20,ROCK1,SRC,CFL1,GORASP2,AKT1,CCNB1,PTPN11,ATP1B3,LDLRAD4,RUVBL2,S100B,CD83,TFG,EPHA4,VDAC1,ROCK2,TMEM59,TOP3B,NAA16,CRKL,HGS,NUDT19,PLS3,FGF10,RAB4A,NRSN1,CORO1C,TRAPPC10,STX5,TNIK,HSP90AB1,EIF2S1,PPFIBP1,CTNNB1,DDRGK1,YWHAB,NCK1,RAB5A,OR1M1,MRPS7,TSHR,USP6NL,MTMR6,FGF17,NUFIP2,FAM8A1,FRS3,PAK2,ZMYM2,VDAC2,FGF7,NCKAP1,APEX1,ATP5F1B,MANSC1,CREBBP,CRMP1,SERPINH1,IGF1R,HSD17B10,RAB1A,LTBR,ARF4,ADD2,RIGI,NECAP2,CASK,IZUMO1,SEC23A,CDCA3,PTPN1,SRPRA,EHBP1,CDK9,MAPRE2,SNAP91,CDH11,SPATS2L,TRAPPC4,OSBPL8,ESYT1,TMEM209,NF2,YKT6,PIK3R2,USP8,CNP,MREG,ARHGAP1,SEC22B,MET,RARS1,JUP,CDK1,GOLGA5,PICALM,SYT2,MSN,GAB1,SMAP2,CTNNA1,TUBA1B,FERMT2,VIRMA,SEC63,RPL22,LDHA,TMOD3,COPE,RAB14,YES1,FBXO7,IFNAR1,FLRT3,EPHA2,AP2A1,NRP1,ARFGAP3,LGALS8,BAG2,SCYL2,HSPD1,ZYX,NDUFA4,FGF3,ARGLU1,AP1M1,AHCYL1,IFNGR1,WDR37,STX12,STIM1,RPN1,TSG101,ATP6V1A,DNM2,PHB1,WDR44,RAB11B,OCRL,SNX1,SNX2,FGF1,PIK3R1,STOML2,MRPS26,RASSF8,CDK5RAP3,TRAF6,PPM1B,HADHA,DNAJC3,HTR1A,WASF3,CYFIP2,GINM1,PGRMC1,ARCN1,VAPB,ATP5PO,AP2M1,CD79B,JAK2,GNB1,MB21D2,ACTB,VEZT,NIBAN2,SCN3B,HSP90AA1,SCFD1,BAX |
| 1.169e-04 | -9.05 | regulation of signal transduction by p53 class mediator | biological process | GO:1901796 | 107 | 50 | 18204 | 5365 |
ING2,RPS20,PMAIP1,CDK5RAP3,PML,MAPKAPK5,HAPSTR1,KDM1A,EEF1E1,PRMT6,MAP2K6,PSMD10,RPF2,TRIM24,RRN3,MIR21,RPL23,SNAI2,MLF1,ZNHIT1,ZMPSTE24,SPRED2,DDX5,UBB,USP2,TAF9,MYC,MSX1,DYRK2,TP53,PAK1IP1,EP300,SPRED1,MDM2,RPL26,RNF34,STK11,HNRNPK,RPS15,PRMT5,HEXIM1,SETD9,USP15,RPS7,PIP4P1,NOP53,AKT1,DYRK1A,MIR186,MIF |
| 1.171e-04 | -9.05 | nucleic acid catabolic process | biological process | GO:0141188 | 562 | 206 | 18204 | 5365 |
MAK16,DFFA,SSU72,NOC4L,RNASEH1,ELP3,RPS7,NOL7,INTS12,BRIX1,TYW3,CMTR1,TRMT1L,TRMT112,HNRNPD,EIF4A3,PNRC1,ELOC,PDE12,ETF1,MRM2,CNOT6L,NUDT12,DIS3L,C1D,KTI12,TSR3,GTDC1,RPS16,UTP23,CASC3,VPS54,TRMT10B,RPL7L1,TRIR,TRMT6,RPS28,TSEN34,RPF2,MRTO4,PPAN,RNASET2,PIH1D1,TFB1M,PABPC1,CNOT8,CSTF2T,ZNHIT3,ZNF473,EMG1,RRP7A,INTS10,SMG9,METTL6,CBLL1,TRMT11,UTP25,RPL35A,TSEN54,IMP3,RPS15,POLR2G,TENT2,TRMT13,WDR12,NOP9,APEX1,NCBP2,DDX5,FTSJ1,RPL35,MAGOHB,WDR55,DCP2,KRR1,DTWD2,SUV39H1,CPSF2,UTP15,RPS24,TRMT61A,METTL14,RPP25,TRUB1,LSM6,WDR6,EIF3E,NUDT16,CNOT7,NOB1,YTHDF2,EDC3,UPF3B,DROSHA,EXOSC3,DBR1,DPH3,CLP1,RNASEH2C,NOP53,QNG1,NPM3,GON7,RPP25L,RTCB,DNASE1L1,LSM4,METTL15,EXOSC8,RPL26,ISG20,ZNHIT6,DKC1,RBM7,MAGOH,CNOT2,WTAP,CSTF3,GRSF1,DTWD1,GTF2H5,KARS1,SKIC8,POP7,HSD17B10,RPF1,TRMT5,LSM2,RPRD1B,RPP21,RIOK2,NSA2,RPL27,EXOSC4,TMT1A,RPL7,FEN1,IMP4,ZCCHC7,DICER1,HNRNPAB,QTRT2,PYM1,CNOT6,NHP2,BUD23,TSR2,PELO,INTS6L,FTSJ3,SRFBP1,PPP1R8,WDR3,CTU1,RPRD1A,METTL25B,RCL1,THUMPD1,TENT4A,OSGEP,PWP2,DUS4L,OSGEPL1,THRAP3,POP5,RPS17,RNASEL,RPS14,RNASE6,PELP1,DDX1,TYW5,RTRAF,UTP6,LSM5,VIRMA,NOP58,AGO1,ADAT1,MPHOSPH6,SMG8,NGDN,LSM10,WBP11,YBEY,WDR82,ELP6,FAM98A,CDC73,RNF113A,METTL2A,RBM34,MEPCE,THG1L,TRMO,LYAR,URM1,PAPOLA,FCF1,SMG5,RC3H2,RPL7A,EXOSC1,MPHOSPH10,DXO,RPP14 |
| 1.173e-04 | -9.05 | oxidoreduction-driven active transmembrane transporter activity | molecular function | GO:0015453 | 55 | 30 | 18094 | 5411 |
COX8A,COX6B1,COX5A,UQCRC1,NDUFS3,NDUFV2,NDUFB6,NDUFA12,NDUFS6,NDUFB10,NDUFA1,COX4I2,NDUFB8,NDUFA2,COX4I1,COX7B,NDUFS8,CYB5A,NDUFC2,NDUFA5,NDUFB4,NDUFS2,CYB561D2,NDUFB5,NDUFA4,NDUFB7,UQCRH,COX7A1,CYBRD1,CYC1 |
| 1.177e-04 | -9.05 | FGR (FGR proto-oncogene, Src family tyrosine kinase) | protein interactions | 2268 | 87 | 41 | 19454 | 5460 |
AIP,H2AZ1,HCLS1,CORO1C,ACTB,YES1,TCP1,SMURF1,CDK9,NR1I2,CCT7,SRC,HSP90AB1,CSK,HNRNPC,SKAP2,AR,CCT2,GSTO1,CBL,HSP90AA1,FGR,RPL23,HSPB1,CCT8,HNRNPA2B1,PRPSAP1,BAG2,KIT,RANBP10,CCR3,RIGI,PRPS1,VDR,SYK,FASLG,CCT5,CDK4,CDK1,HEXIM1,MET |
| 1.179e-04 | -9.05 | RGS7 (regulator of G protein signaling 7) | protein interactions | 6000 | 20 | 14 | 19454 | 5460 |
YWHAB,GNAI3,GNAZ,GNAQ,PRKCA,HSP90AA1,SNAPIN,CHRM3,CCT5,CSK,CHRM1,MSX1,GNAO1,CHRM5 |
| 1.179e-04 | -9.05 | DENND1B (DENN domain containing 1B) | protein interactions | 163486 | 20 | 14 | 19454 | 5460 |
ARF4,VIRMA,FKBP8,HNRNPL,S100A6,ARF1,RAB35,YWHAB,YWHAZ,YWHAH,XPO1,YWHAG,RBFOX2,SFN |
| 1.180e-04 | -9.04 | purine nucleoside triphosphate biosynthetic process | biological process | GO:0009145 | 86 | 42 | 18204 | 5365 |
ATP5PF,NDUFC2,NDUFS6,NDUFAB1,NME1,SDHC,NDUFB10,ATP5F1A,NDUFS8,NDUFA1,NDUFB8,NDUFA2,ATP5MC3,NDUFB7,NDUFA5,NME2,LIPA,SDHB,NDUFA12,ATP5MK,COX11,ATP5PO,ATP5MG,ADK,NDUFS2,DNAJC30,STOML2,NDUFB4,UQCC3,ATP5PB,ATP6V1A,NDUFS3,ATP5PD,NUDT2,ATP5F1E,NME4,ATP5F1B,NDUFV2,ATP5F1D,NDUFB6,ATP5MC1,NDUFB5 |
| 1.180e-04 | -9.04 | METTL15 (methyltransferase 15, mitochondrial 12S rRNA N4-cytidine) | protein interactions | 196074 | 273 | 105 | 19454 | 5460 |
MTRES1,HECTD1,QRSL1,MRPS34,NDUFAB1,FAXC,MND1,MRPL10,POLDIP2,MRPL20,MRPL40,MRPL41,MRPL17,PDHB,NME4,DLAT,TWNK,ANAPC16,AMACR,DVL2,MRPS16,TUFM,PYCR2,EMILIN1,NDUFAF2,FGFR1OP2,MRPS21,ACAT1,MRPS28,MRPL53,MSRB3,MRPL49,VAC14,NDUFS3,BCS1L,HADH,PPIF,MRPL47,NDUFA2,ATP5PB,MRPL22,MRPS18C,MRPS33,PDE12,BSCL2,MRPS18B,ATP5PF,KLHL22,LAMP3,GRSF1,MRPL24,MRPS23,SLAIN2,MALSU1,DBT,MRPL50,SYNCRIP,MRPS9,NDUFA5,MRPS18A,MRPL12,MRPS7,SLC15A1,NDUFS2,HADHA,ATP5IF1,EXD2,CXCR4,MRPS25,HNRNPAB,CUL3,PYCR1,PMPCA,MTG2,AUH,NDUFAF4,APLNR,MRPL23,ATP5F1B,MRPL13,DLST,TACO1,NDUFA12,PDHA1,NDUFS6,ETFB,HNRNPDL,MRPS17,KGD4,ATP5F1D,ETFA,MRPS11,COX8A,HINT2,MRPS26,MRPL9,NDUFV2,STOML2,MRPS35,OPRL1,NDUFS8,HNRNPL,GATD3,FAHD1,PHB1 |
| 1.182e-04 | -9.04 | IKBIP (IKBKB interacting protein) | protein interactions | 121457 | 163 | 68 | 19454 | 5460 |
HYPK,CGAS,SNX2,DNAJB9,LCA5L,FIBIN,PCDH9,DNM2,SYNCRIP,RB1CC1,FAM20C,EXOC1,TPM3,DNAJC30,BLOC1S2,DISC1,H2BC1,EZH2,IFT57,RPN1,AP2S1,COMMD8,CDK4,RAF1,SERPINB9,CCDC47,SNAPIN,RANBP6,VIRMA,NCKAP1,BORCS7,DYRK1A,PPP1R10,RAN,SEC61B,SFXN2,TRAF7,PSMC5,DNAJC10,CALU,MORF4L1,TMED4,NDUFB6,GPM6A,NF2,CYFIP2,KDM1A,HSPA5,CERS6,TMEM106B,RPA3,DNAJC3,BAP1,ARRDC3,HSPA8,BORCS5,RPA2,P3H1,AGGF1,TFIP11,VPS54,FHOD3,NUP62,ATG16L1,DUSP22,ST7,OTULINL,SEC62 |
| 1.182e-04 | -9.04 | CRYAB (crystallin alpha B) | protein interactions | 1410 | 163 | 68 | 19454 | 5460 |
VEGFA,ALB,PSMD4,CD40LG,DES,CRYBB2,CCDC85B,BAG3,GORASP2,ISCA2,CRYBA1,BAX,SORD,CSGALNACT1,SOD1,FOS,TMEM168,HSPB2,HSPA8,SQSTM1,PSMA3,B2M,CCND1,HSPB6,KRTAP8-1,CRYAB,STX17,APOC2,TRAPPC6A,SCG5,PRNP,PRELID1,PTDSS1,HSPB8,FCGR2A,CTNNB1,CRADD,UBE2D1,SMAD4,TIAM1,CASP12,HBA1,LYZ,CDC23,BCL2L1,HSPB1,AGPAT1,MAP1B,FSTL1,OAZ3,SLC25A32,G3BP1,TFG,MDC1,CRYGD,KBTBD4,TP53,MRPL11,LBH,SOX2,FCF1,TNPO2,VPS33A,TMEM31,NEFL,DISC1,BMPR2,CCR1 |
| 1.183e-04 | -9.04 | regulation of mRNA catabolic process | biological process | GO:0061013 | 290 | 115 | 18204 | 5365 |
MIR206,FXR2,MIR373,MIR181D,PRKCA,MIR214,CIRBP,HNRNPA0,MIR320A,MIR20A,MIR497,HNRNPAB,VIP,CNOT6,CASC3,MIRLET7B,MIR130A,MIRLET7C,MIR125A,TIRAP,MIR708,IGF2BP1,TENT5C,MIR200C,MIR424,PABPC1,HNRNPC,ZC3H14,MIR491,MIR16-1,DHX9,AKT1,BOLL,ELAVL4,YTHDF1,MIR495,MIR23A,MIR211,MIR98,LARP4B,PRR5L,EXOSC8,GTPBP1,MIR24-1,MIR192,ROCK2,MAGOH,CNOT2,PDE12,CNOT6L,MIR9-1,TNRC6C,HNRNPD,EIF4A3,MIR145,TRAF2,MIR191,MIR342,MYD88,MIR106A,SYNCRIP,ALKBH5,BTG2,MIR625,DCP2,MIR100,MIR193A,MIR96,MIR30B,METTL14,MIR519D,MIR146A,MIR149,MIR212,MIR204,MIR423,MIR181C,CNOT7,RC3H2,FASTKD5,MIR137,IREB2,EXOSC3,MIR195,YTHDF2,MIR210,MIR885,MOV10,CNOT8,MIR340,NRDE2,MIR26B,MIR190B,TENT4A,MIR140,POLR2G,MIR130B,CARHSP1,RNASEL,PCBP4,MIR185,APEX1,TENT5D,MIR106B,THRAP3,MIR34B,MIR223,PAIP1,MIR135B,MIR142,MAGOHB,AGO1,TRAF3IP2,ROCK1,MIR1-1 |
| 1.186e-04 | -9.04 | MAP3K11 (mitogen-activated protein kinase kinase kinase 11) | protein interactions | 4296 | 58 | 30 | 19454 | 5460 |
KIF3B,HSP90AB1,ESR2,STUB1,DLG4,GSK3A,RAC2,IKBKB,RHOG,TRAF6,YWHAZ,HSP90AA1,CBL,RB1CC1,AKT1,ATG9A,EPS8,HPCA,COPS5,MAP3K21,RIGI,MAP3K11,TRIM5,MAP3K12,MAP2K1,TOP3B,NCALD,TRAF2,CDC42,HPCAL1 |
| 1.186e-04 | -9.04 | Synaptobrevin | pfam domains | PF00957 | 10 | 9 | 17795 | 5224 |
VAMP3,VAMP7,VAMP2,VAMP1,STXBP6,SEC22B,VAMP8,YKT6,VAMP5 |
| 1.189e-04 | -9.04 | LINC01554 (long intergenic non-protein coding RNA 1554) | protein interactions | 202299 | 140 | 60 | 19454 | 5460 |
CCT7,G6PD,KRT8,KPNA1,PSMD7,POR,GAPDH,XPO1,RPL6,PDIA3,KARS1,EIF3E,OLA1,G3BP1,HNRNPF,IDH1,DHX9,RTCB,PDIA6,ERO1A,SEPTIN7,PABPC1,HSPD1,BZW2,GDI2,TUBB4B,PGM1,EEF2,TUBA1A,PPP2R1A,TXNRD1,RPSA,APEX1,ACTB,TUBB,EIF4A2,MSN,GANAB,ENO1,SERPINH1,HSP90AA1,CCT2,TUFM,ATP5F1A,PMPCA,HSPA5,PSMC1,OXCT1,EEF1G,GTF2I,SQSTM1,RTN4,PGK1,HSPA8,XRCC5,DDX46,KRT7,EIF4B,HSP90B1,ARHGAP1 |
| 1.194e-04 | -9.03 | MCTS1 (MCTS1 re-initiation and release factor) | protein interactions | 28985 | 109 | 49 | 19454 | 5460 |
CYP1A1,UBE2H,MTPN,USP5,NFKBIA,TNFRSF1B,RPS3,NIPA2,VAMP3,RPS12,ZMAT2,RPS20,ISOC1,METTL14,RPA2,UBE2M,ATG16L1,RPS14,RLN2,SNRNP27,HSCB,RPS28,BAP1,NCDN,RPA3,STK26,AGR2,SMAD4,AVL9,RPS2,XPO1,RPS10,RPL35A,NUP35,ZBTB2,DHX15,CORO1C,GPX7,TUBB4B,RPS23,CCR1,CENPM,METTL26,RPSA,RPS7,GTF2E2,OTUD6B,EIF2D,NAE1 |
| 1.194e-04 | -9.03 | WRNIP1 (WRN helicase interacting protein 1) | protein interactions | 56897 | 109 | 49 | 19454 | 5460 |
LMNA,RPA2,WWP1,METTL14,ELP3,EYA3,COIL,RPA3,POLD2,NLE1,PML,IRF3,NUP50,MAVS,BRCA1,DCAF4,MYO6,SMAD2,POLD4,ZBTB38,COP1,MYC,CUL3,PIK3R3,FOXA3,AR,SNRNP40,ESR2,CCNF,CPSF1,LMBR1L,TUBA1B,FOXP3,CBX3,HDAC11,OTULIN,KDM4B,NUP107,TNF,TOLLIP,ADIPOQ,SRSF4,IMMP2L,RIGI,PCNA,TRAF6,XPO1,EGLN3,CDC5L |
| 1.196e-04 | -9.03 | STAT5B (signal transducer and activator of transcription 5B) | protein interactions | 6777 | 123 | 54 | 19454 | 5460 |
SNX3,RBBP4,STAT1,STAT5A,SRC,JAK2,NMI,TOM1L1,SURF2,IL2RA,ATG3,IL15,NIF3L1,PTPN11,IL2RB,PIK3R3,KANSL3,MCMBP,PDHB,CXCR4,RPA3,EP300,DLAT,RPRD1B,RPA2,UBE2M,CDKN1A,LMO4,HNRNPL,AFTPH,PGR,RPRD1A,PTPN1,SHC1,CD247,CBL,HAX1,ANKMY2,USP2,TPM3,SERTAD1,TRMO,KIT,FLOT1,TFG,SOCS2,HNRNPA2B1,CCR5,JAK1,PDHA1,CTLA4,PSMC3,CRKL,GHR |
| 1.196e-04 | -9.03 | VKORC1 (vitamin K epoxide reductase complex subunit 1) | protein interactions | 79001 | 123 | 54 | 19454 | 5460 |
CCDC167,PLP2,TRAM1,MANBAL,LMNA,VAPB,STAT6,CAV2,JAGN1,SAT1,TMEM256,KCNK17,HSCB,FTL,CSK,CREB3,SLC25A1,SPOP,ILK,FIS1,ATP5MC3,APOC4,LMBR1L,RMDN3,ATP6AP2,ESR2,VKORC1L1,TMT1B,MSRB1,TMEM176A,SURF4,SERPINA1,SPTSSA,PDIA6,YIF1A,TF,GJB1,SLC7A14,DPM2,CD81,HDAC6,PPIB,HP,CD9,CDC23,CNN3,MT1X,COMT,CD63,ECHDC1,ARL6IP5,OS9,MSMO1,TMEM45B |
| 1.198e-04 | -9.03 | CREBBP (CREB binding protein) | protein interactions | 1387 | 557 | 196 | 19454 | 5460 |
SUV39H1,IRF9,ERCC3,EID1,MED21,TIAM1,MYBL2,LDLR,SMAD3,ACTA2,CITED1,MDM2,CDK9,ZBTB2,KLF1,EEF1A1,ING1,SMAD1,SOX9,YTHDF2,TOPORS,HOXD12,FAF1,EGR1,MDC1,MSH6,SERTAD1,HUWE1,RUNX1,ZCCHC12,USP14,PPP1CC,NONO,KPNA6,AR,CDC16,CSK,SMAD2,RPS20,UBE2I,TRIM24,PELP1,JUNB,VIRMA,DEK,ZBTB17,CCNA2,CDK7,CPSF4,CCND1,NFYB,JUP,SNAI2,MTDH,PIAS1,IRF7,HMGB1,EIF3D,HMGA1,DYRK1B,RB1CC1,CAMSAP2,CDK5RAP3,UBE2D1,KDM2A,COPS2,EGLN3,NUP35,CCAR2,SPTAN1,JUN,MAPK10,HOXB1,VDR,RBPJ,PCNA,BAG2,TRIP4,ATF3,RBBP7,PCGF3,PROX1,IRF1,ATF1,NFYA,HNF1B,PYCR1,CUL3,SP1,BRCA1,UBE2S,RPL35,RBBP4,TUBB,ACTB,CDKN1A,WDR77,ANXA7,PPARG,MED23,RNF7,SERTAD2,CCND3,TNFSF10,CSNK2A1,XAF1,SMAD4,H2AC4,GTF2B,EGR2,SNAPC5,TP53,HBP1,CDK8,NFE2L2,ACVR1,SOS2,RPL3,SNIP1,MAP1B,ZNF451,H3C1,KPNA2,RBCK1,EXOC5,AKT1,ATF4,PTTG1,SERTAD3,POU1F1,CSNK2B,PSMC5,CREB1,CDC20,SRC,DYRK1A,GABPA,PLAGL1,FBXL19,MAFG,PPP1R8,SUMO1,STAT6,KLF4,RPA2,FGFR1,TLR2,BAP1,IRF3,PML,BCL6,BNIP3L,HDAC3,YWHAH,CTNNB1,LAMP2,MGMT,HSPB1,IKBKB,ZHX1,RXRG,RBM5,ELK1,HMG20A,HNRNPL,EEF2,HEXA,SMARCB1,EWSR1,PAX6,NFE2,RUVBL1,CHRDL1,HLF,BRMS1,MYC,CREBBP,PAPOLA,ICAM1,ATG3,ZMYM2,GTF2F1,ANAPC2,ESR2,STAT2,STAT1,ZCCHC7,MTF1,GSTO2,CTBP1,HSPA8,EP300,DDIT3,DDX5,FOS,MSX1 |
| 1.204e-04 | -9.02 | PIKFYVE (phosphoinositide kinase, FYVE-type zinc finger containing) | protein interactions | 200576 | 43 | 24 | 19454 | 5460 |
VIRMA,CBX5,ESD,MIR140,LAMTOR1,FIG4,LAMP3,LAMP2,ATG9A,BCL6,NPTN,KRAS,H3C1,RAB9A,RAB5A,CDK5,VAC14,RAB4A,VPS33A,TIMM23,ATG16L1,PTAR1,TOP3B,WDR83 |
| 1.204e-04 | -9.02 | EXOC6B (exocyst complex component 6B) | protein interactions | 23233 | 43 | 24 | 19454 | 5460 |
RPA3,EFNB1,RPA2,CA14,EXOC3,CAPZA2,EFHD1,FAM234A,IL1R2,CDK7,RALA,HNRNPL,VIRMA,SCN2B,CMTR1,LURAP1,RPS20,SMAD4,EXOC2,EXOC8,KXD1,RAB11A,EXOC5,EXOC1 |
| 1.208e-04 | -9.02 | ATP6V0D1 (ATPase H+ transporting V0 subunit d1) | protein interactions | 9114 | 166 | 69 | 19454 | 5460 |
RPS16,UQCRH,TMPO,PTPN1,THOC2,ACSL4,ATP6V1A,RPS2,ATP6V1D,NDUFB8,TMEM199,PSMD3,RAB5C,SLC38A7,LAMTOR2,COPS5,SLC38A9,KRAS,ATP1A2,ATP5F1D,VDAC1,TOMM6,SLC25A5,RPN1,SMARCB1,STX12,OTULIN,B3GNT2,ATP5PB,MVD,NDUFA2,MTCH2,FNTB,ATP5F1B,SLC25A4,UBB,ATP6AP2,ESR2,VDAC2,VAMP3,MID1IP1,CYB5R3,ATP1B3,ATP1A3,ATP1A1,VMP1,RIT1,NDUFB7,RAB2A,TOMM40,ATP5F1A,EMC1,ADRB2,STAU1,ATP6V1G1,RPA3,INPPL1,HSPA8,TMEM185A,ATP5PO,PAK2,RPA2,CDK1,SSR1,LEPR,PRKAB1,ATP6V1C1,TOMM22,GABARAPL2 |
| 1.208e-04 | -9.02 | KRI1 (KRI1 homolog) | protein interactions | 65095 | 219 | 87 | 19454 | 5460 |
RAB11A,MYC,DNAJB6,CDKL2,H1-1,DCAF4,ZCRB1,PSMD14,MYO6,PSKH1,RPS9,RPL19,RPL10,APEX1,RPL35,SNRNP40,SYK,PABPC5,EP300,NOP53,DDRGK1,RPL6,IFI16,LHX2,MRPL18,DDX23,PHB1,SRSF1,RPL7,LYAR,RPS10,H1-3,SOX2,RAF1,CHMP4C,RPS24,RPL31,G3BP1,H1-6,CEP70,RPL26,RPL7A,UBE2H,RC3H2,FGFBP1,EIF2AK2,ZNF330,CCNF,RPS3,SRPK2,DYRK1A,RPL13A,RPS14,RPLP0,HEXIM1,ZNF574,RPA2,NLE1,SIRT7,RPA3,AATF,UTP23,RPL4,NPM3,E4F1,DPP4,NOL12,RPS2,MPHOSPH10,SNRNP70,PRR3,KRR1,KLF9,ZBTB2,SURF6,RPS16,FZR1,AURKAIP1,H2AX,APOBEC3D,RPSA,LLPH,RPL3,RPL23A,RPL17,RPS13,H3C1 |
| 1.212e-04 | -9.02 | SLC7A2 (solute carrier family 7 member 2) | protein interactions | 6542 | 98 | 45 | 19454 | 5460 |
LGALS3,RHOJ,GPR17,RAB11A,RAB2A,RHOB,LAMTOR1,TSPAN15,CD40,CXCR4,RHOU,RAB5A,CYP2C18,VIPR1,TSPAN5,STX7,ATP6V0E1,RND2,HCST,SEC62,CDC42,VAPB,RAB35,RAC2,RNF128,RHOH,ARF6,CAV1,DIRAS3,STX6,RAB5C,TSPAN10,LAMP2,DLK2,LAMP3,RHOG,UPK1A,CD83,RAB3B,KRAS,TP53,YIPF3,RAB4A,AQP3,SMARCB1 |
| 1.212e-04 | -9.02 | C3AR1 (complement C3a receptor 1) | protein interactions | 719 | 98 | 45 | 19454 | 5460 |
SNX14,SNTA1,HMOX2,RAB2A,VEZT,ATP5F1B,LRRC8A,SC5D,GPR89A,ADGRL3,GOLGA5,ST7,HACD2,SLC19A2,ZDHHC17,CERS6,CERS2,LPAR1,NDUFC2,SLC35F2,TMEM160,HSDL1,HELLS,ABCB9,TSPAN15,FITM2,FAM241A,ORC5,SLC25A17,MSMO1,RMND1,TLCD4,SPPL3,PEX13,GNPAT,PTPN1,NDUFA12,YIPF3,MACO1,ATP5PB,TCAF2,LPCAT3,B4GALT7,NDUFB5,ATP2B4 |
| 1.212e-04 | -9.02 | NUDT16L1 (nudix hydrolase 16 like 1) | protein interactions | 84309 | 98 | 45 | 19454 | 5460 |
MIRLET7D,ESR2,TCEAL1,MIRLET7B,CCNF,PNMA1,MIR363,MIR145,MIR98,NTAQ1,FBXO7,CUL3,MIR7-3,HNRNPH2,MIRLET7I,RPA3,MIR21,CRYAB,TIMM23,RPA2,TRIM68,MIR34B,SLC25A12,CAND1,SPPL3,MIR9-1,MIRLET7G,SNRPA1,MIR25,MIR141,MIR34A,MIR31,SNRNP70,COPS5,MIRLET7C,HNRNPF,NEDD8,TRIM11,MAP1B,NUDT16,TRAF2,SOX2,MIR200C,RAF1,E2F4 |
| 1.221e-04 | -9.01 | EIF3L (eukaryotic translation initiation factor 3 subunit L) | protein interactions | 51386 | 234 | 92 | 19454 | 5460 |
EMC9,EIF4B,EIF1B,STAU1,G3BP2,UPF3B,RPS28,HDAC5,TXNL1,EP300,RAB5A,PSMD14,BRCA1,RPS5,HSP90AA1,ICAM1,POLR1B,MYC,RRN3,RIOK2,EIF4A2,ESR2,RPL10,LMBR1L,CMTR1,EIF3K,RPS9,SEC61B,EZH2,SART3,SOX2,KRAS,G3BP1,RPS4X,PSMD12,SSRP1,PABPC1,AHSA1,DRG1,IFI16,WWP2,XPO1,EIF3D,DNM2,RPA2,METTL14,UBE2M,HEXIM1,ATG16L1,EIF3J,CFTR,EIF4E,HSPA5,RGS2,BAP1,RPA3,PML,SIRT7,EIF3G,SMAD2,UBE2H,VIRMA,PSPC1,CCNF,METAP2,RPS20,DNAJC2,SRP72,RNF8,TP53,H2AX,EIF4EBP2,TOLLIP,RPS13,EIF3E,HAPSTR1,SNRNP70,CALR,ENY2,EMC4,USP2,CD81,CSNK2A1,HDAC6,FZR1,PPP1R18,RPS16,EIF2B5,RBM42,TMPO,HRAS,COQ8A |
| 1.222e-04 | -9.01 | BARD1 (BRCA1 associated RING domain 1) | protein interactions | 580 | 319 | 120 | 19454 | 5460 |
DRG1,SKIC8,UBE2D1,TRA2A,UBE2E2,HMGA1,DDX50,NPC2,TMEM248,SRSF10,HNRNPL,HP1BP3,ZHX1,FEZ1,SRSF1,SMARCB1,MTA2,DCAF8L2,E2F4,SUPT5H,TRMT1L,HNRNPDL,TFG,RFC2,FKBP2,CCAR1,SRSF4,MCM6,KRAS,UBE3A,SRSF7,EWSR1,TOP2B,BRCA1,YWHAZ,RBBP8,CIRBP,TBC1D1,SNRPB,CPSF2,SAMHD1,HNRNPC,OST4,LRIF1,POLR2B,CBX5,MED17,LGALS3,NFKBIA,FKBP1A,MFAP1,AKIP1,MT2A,PTN,UBE2D3,TRA2B,SRSF2,ZFP64,XRCC5,DDX39B,USP15,TOPBP1,CDK12,AKAP8L,SMCHD1,SNRNP70,H2AC4,TUBG1,ATP1B1,GPRASP2,RBM17,MOV10,NFKB1,CDK9,TOP1,TNKS,GNPAT,UBE2N,RNF8,CBX3,H2AX,TP53,MDC1,MSH6,MEPCE,OLA1,THRAP3,H3C1,NKRF,CDKN2AIP,UBE2E3,LGALS8,DCAF16,ATP1B3,PPP1CC,CEP70,FBXO44,EXOC5,HSPA14,TRAF1,SRPK2,BCCIP,DYRK1A,SNX3,RPS20,ZNF655,MACROH2A1,MOB4,LUC7L3,CDK1,GTF3C4,UBE2W,ING5,PIAS1,LDOC1,RBM22,UBE2K,NPM3,NBN,PPM1G |
| 1.231e-04 | -9.00 | LDAF1 (lipid droplet assembly factor 1) | protein interactions | 57146 | 53 | 28 | 19454 | 5460 |
COQ8A,CYB5R3,HSD17B11,SEC61B,MB21D2,RAB14,RAB1B,TMEM19,RAB5C,FAM241A,STN1,ENDOD1,IL17F,COP1,S100B,TMT1A,BSCL2,GAD2,GIMAP2,RNF26,MTMR6,SLC19A2,SEC62,SEC22A,FAF2,SLC48A1,EZH2,USE1 |
| 1.231e-04 | -9.00 | ZBTB17 (zinc finger and BTB domain containing 17) | protein interactions | 7709 | 53 | 28 | 19454 | 5460 |
HUWE1,GTF2I,TRIM63,BCL6,DVL2,HAPSTR1,RLIM,PMAIP1,EP300,IRF8,MAGEA4,ITGB5,E2F6,MAX,TP53,NOTCH2,GFI1,CDKN1A,MSX2,ZBTB17,PGR,ESR2,HSP90AA1,HSPB1,TOPBP1,MYC,CREBBP,CUL3 |
| 1.231e-04 | -9.00 | RIC3 (RIC3 acetylcholine receptor chaperone) | protein interactions | 79608 | 53 | 28 | 19454 | 5460 |
STX7,PIP4P1,RIGI,TMUB1,PHB2,HSPA8,YIF1A,TAPT1,STX12,TMBIM1,ST7,ERLIN2,MTCH2,GOSR2,RMND1,ACTB,SLC30A7,FA2H,TRAF3IP3,PHB1,BCL2L1,TMEM11,ATP1A3,AGR2,RIC3,FATE1,NCAPG2,SLC30A5 |
| 1.231e-04 | -9.00 | UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X) | protein interactions | 29796 | 53 | 28 | 19454 | 5460 |
NRP1,RIT1,AGR2,DDRGK1,COX6B1,MOV10,RALB,RAB11A,EGLN3,UQCRH,UQCRQ,CYSTM1,VIRMA,TAX1BP1,UQCRC2,CCNF,CYC1,RPA2,NDUFS3,UQCRC1,TIMMDC1,E2F4,RIGI,KRAS,UFL1,GPM6A,OLFML3,RPA3 |
| 1.231e-04 | -9.00 | SUCO (SUN domain containing ossification factor) | protein interactions | 51430 | 53 | 28 | 19454 | 5460 |
DNAJC1,ISG20L2,TMPO,SEC63,APEX1,ZBTB2,RPL10,PTPN1,HSD17B11,PREP,SEC61B,YWHAZ,YWHAB,CALU,YWHAG,YWHAH,PXMP2,BAP1,TRAPPC1,TMT1A,RPN1,TIMM23,SSR1,TAPT1,SLC35F6,SEC62,DNAJC25,ST7 |
| 1.231e-04 | -9.00 | IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma) | protein interactions | 3421 | 53 | 28 | 19454 | 5460 |
IDH1,EP300,HSPD1,PRKD3,PPP1R12A,IDH3A,PQBP1,MRPS7,KPNA2,FBXW7,HNRNPK,ADRB2,IDH3B,EDF1,SPR,EZH2,IDH2,FAHD1,CCNF,MALSU1,APEX1,RPL35A,ACO2,MYC,SUGP1,CIAO1,AHSA1,POU5F1 |
| 1.232e-04 | -9.00 | SAP130 (Sin3A associated protein 130) | protein interactions | 79595 | 169 | 70 | 19454 | 5460 |
VIRMA,ESR2,BCCIP,DYNLL1,RBBP4,ACTB,ING2,SNRPD1,TNFRSF1B,LURAP1,SP1,H1-1,CFL2,MCM4,AR,MYC,HNF1B,SFN,CUL2,MBD3,TGIF2LX,SF3B1,RNF113A,NUP50,PML,PAX9,HECTD1,LMNA,KLF3,MXD1,SUPT3H,KLF9,NUP35,HNRNPL,BRMS1L,SHPRH,MYBL2,EED,GATAD1,RB1,SMAD3,SIN3A,YWHAB,COPS5,PHF1,PSMD12,MCM6,PAX6,RBBP7,G3BP1,ASF1A,HNRNPK,RPAP3,TGIF2,KLF10,ZRANB2,HBP1,MTA2,TAF10,CBX3,ING1,SOX2,RPL29,H2AX,SAP30,MTA3,MAX,PHF23,ZNF704,CCT5 |
| 1.234e-04 | -9.00 | nitric oxide metabolic process | biological process | GO:0046209 | 30 | 19 | 18204 | 5365 |
CYP1B1,MTARC2,ACP5,TLR2,AKT1,SPR,CAV1,TICAM1,DDAH1,NOS1AP,NQO1,CYB5R3,CYB5B,TLR4,CYP1A1,PPARA,TLR6,ARG2,CYGB |
| 1.234e-04 | -9.00 | positive regulation of defense response to virus by host | biological process | GO:0002230 | 30 | 19 | 18204 | 5365 |
TRIM22,SIN3A,RIGI,PQBP1,STAT1,MAVS,IL12B,LILRB1,TRIM44,IL23A,APOBEC3F,TRAF3IP2,TOMM70,HSP90AA1,CGAS,PYCARD,APOBEC3G,SELENOK,TRIM6 |
| 1.234e-04 | -9.00 | transcription initiation at RNA polymerase II promoter | biological process | GO:0006367 | 126 | 57 | 18204 | 5365 |
GTF2A2,POLR2G,MED22,APOBEC3C,SGF29,MED21,GTF2F2,MED11,MED30,POLR2D,MED10,GTF2H2,PADI2,ELOC,MED23,MED9,GTF2F1,TRMT112,TAF9,VPS72,SIRT7,GTF2H5,APEX1,TP53,MED17,ERCC3,GTF2B,DPY30,TAF10,TAF7,DR1,EP300,CDK7,POLR2I,NIBAN2,APOBEC3F,TAF2,PAAF1,CCNH,ZMPSTE24,APOBEC3A,OGG1,GTF2A1,MED27,GTF2E2,MACROH2A1,SMARCB1,WBP2,SPHK2,EGR1,CDK9,MED29,TAF11,MED4,MNAT1,MED31,GTF2E1 |
| 1.241e-04 | -8.99 | TFE3 (transcription factor binding to IGHM enhancer 3) | protein interactions | 7030 | 48 | 26 | 19454 | 5460 |
LAMTOR3,MITF,TFEB,TFE3,SMAD3,AKR1B1,FBXW11,SMAD4,CUL2,XPO1,YWHAG,SMARCE1,BTF3,PHB2,HMGB1,NEDD8,RIGI,RPA3,EWSR1,HDAC5,KLF3,IRF8,RRAGA,TOP3B,KLF12,SOX2 |
| 1.241e-04 | -8.99 | RITA1 (RBPJ interacting and tubulin associated 1) | protein interactions | 84934 | 48 | 26 | 19454 | 5460 |
PSMB7,RBPJ,PSMC3,PSMC4,PSMB3,PSMB9,PSMA2,PSMA1,PSMA5,PSMD12,PSMC1,MAIP1,PSMA3,PSMD10,PSMD14,PSMB2,PSMD3,PSMA4,PSMD1,PSMD6,PSMB6,PSMB4,PSMB5,PSMA6,PSMC5,PSMB1 |
| 1.242e-04 | -8.99 | HDAC1 (histone deacetylase 1) | protein interactions | 3065 | 1067 | 353 | 19454 | 5460 |
ADNP,PPARG,LMO4,TIMM13,UNC45A,TNFSF10,COIL,PSMC1,NUP50,LMNB1,PFDN6,SP1,CUL3,IKZF2,MCM4,RNF40,RBBP4,DYNLL1,TNPO3,PARP2,RAN,FOXP3,EZH2,CDK5R1,RBPJ,E2F4,SAP30,GFI1,RBBP7,G3BP1,PCGF6,ATF3,SLC39A7,PSMD10,HR,PRPF19,CCAR2,SPTAN1,PHB1,WDR6,SNAI2,JUP,TOX4,IFRD1,CCND1,BRINP1,ATG16L1,EID2,SNAI3,HMGB1,SMC4,DESI1,NUCKS1,GTF2I,SS18,MBD3,MYH2,CCSAP,SQSTM1,TXNIP,STK24,NAPA,PPP1CC,KPNA6,NONO,AR,RUNX1,LDHA,ZNF507,SMAD5,UBE2I,UBASH3B,GSK3A,GANAB,DMAP1,SAP30L,PHF23,TBK1,MTA3,SMAD1,ING1,MAP1LC3B,BACH1,CAMK2G,MSH6,RNF20,HSD17B10,PC,RING1,TLE1,NFKB1,ZMYND11,KLF1,ZBTB2,EHBP1,AIFM1,H2AZ1,SRPRA,MXD1,NACC2,CTBP1,TPD52L1,STAU1,SAP18,ZBTB5,RFC4,YAF2,EP300,AKAP1,DDIT3,HSPA8,HDAC5,FTSJ3,S100PBP,RBBP8,PAPOLA,PCCB,BRMS1,USP38,MORC4,NFKBIA,PHF12,ZHX3,PHF21A,KCTD11,CRKL,MTA2,ARFGEF1,CSTF2T,TNPO2,SOX2,SATB1,HIGD1C,ZNF609,RERE,CCT8,TOP2B,RTCB,RUVBL2,RPAP3,HSPB1,TCP1,HMG20A,ELK1,NKX3-1,ZHX1,EED,IDH2,VPS4B,RPA2,ACACA,HECTD1,E2F6,HEXIM1,UBE2M,KDM1A,HSPA5,EID2B,BANF1,RNF113A,NR2E1,MORF4L1,ADRM1,GABPA,BUB3,ZBTB33,CREB1,MOB4,ING2,NFE2L2,TFCP2,NKX3-2,TBC1D4,PSMC3,TAB2,CDK4,RAP1A,ZMYM3,ACTR1A,TMEM33,KPNA2,H2BC14,SLC16A1,SNRNP70,SMAD4,USP15,GPRASP2,CSNK2A1,COPS5,ARL6IP5,H2AC1,CRYAB,SLC25A3,PGRMC1,ACTL6A,CDKN1A,MYH1,TGIF2LX,ZFP64,BRCA1,HSP90AA1,PFDN2,PFDN4,NFYA,SMARCE1,TUBB,ACTB,SNRPD2,CHMP4C,SKA3,RPS11,RAF1,HSDL2,JUN,PPP2R1A,MAPK10,CDK20,ZNF592,ZBTB16,RAD21,OVOL1,AHCYL1,RPS27A,HSPD1,NEK9,SLC25A5,BAG2,PCNA,ELP6,HNRNPD,VCPIP1,RB1CC1,GOLGA5,DCTN4,HAUS2,NFYB,SF3A1,IRF7,NF2,MEF2A,RPA3,DVL2,HELLS,BAHD1,SMAD2,ZNF687,VIRMA,PDCD5,ENO1,TUBA1B,CCNF,TRIM27,CCT5,GPAM,CDK2AP2,TTC4,SMN1,VTA1,TGIF2,CLP1,CNN3,SUV39H1,DERL2,TSC22D3,MDM2,SMAD3,RB1,UBL3,SYK,PHB2,DDX5,CCT2,H1-1,HNRNPC,CREBBP,MYC,BAG3,CPSF2,BTF3,PSMD1,TAX1BP1,MATR3,STAT2,STAT1,ESR2,APEX1,MIDEAS,PRMT5,ZMYM2,H2BC1,TUBB4B,CSTPP1,MOB3C,SMARCB1,RUVBL1,PFDN1,PRDM4,TRIM21,DRG2,DDX1,CDC23,PFDN5,WWP2,CTNNB1,DDRGK1,DNTTIP1,SUMO2,CCT7,TRMT61A,SIN3A,CCDC71,SSR1,KLF4,LUC7L3,PAAF1,CD2AP,HDAC3,BCL6,PML,BAP1,BICD2,MECP2,CCNB1,SMARCA5,ARHGAP21,PLAGL1,STAT5A,CDC20,MACROH2A1,CSNK2B,HEY2,PIK3CA,NUPR1,HBP1,TP53,NEDD8,H3C1,PSMA5,NUP107,PHF1,BHLHE40,CYBRD1,H2AC4,KPNA1,AKAP8L,E4F1,BRMS1L,RPS27L,FZR1,MXI1,LMAN1,ESD,GATAD1 |
| 1.245e-04 | -8.99 | Protein export | KEGG pathways | hsa03060 | 23 | 17 | 7161 | 2463 |
SRPRB,SEC63,SEC61A1,SPCS2,IMMP2L,SPCS3,SEC61G,HSPA5,SPCS1,SRPRA,SEC61A2,SEC11A,SEC62,SRP72,SRP54,SRP14,SEC61B |
| 1.245e-04 | -8.99 | Protein export | KEGG pathways | ko03060 | 23 | 17 | 7161 | 2463 |
SPCS1,SRPRA,SEC61A1,SEC63,SRPRB,SPCS2,HSPA5,SEC61G,IMMP2L,SPCS3,SEC61B,SRP14,SEC11A,SEC61A2,SRP72,SEC62,SRP54 |
| 1.247e-04 | -8.99 | negative regulation of cell cycle G1/S phase transition | biological process | GO:1902807 | 94 | 45 | 18204 | 5365 |
MIR193A,CDKN1B,ACVR1,GPNMB,MIR503,CCND1,CTDSP1,DLG1,RPS27L,CDC73,CCL2,PTEN,MIR137,MIR29C,MIR638,FBXO7,CDKN1A,PML,CRADD,PRMT2,ZNF655,MIR16-1,CACNB4,DCUN1D3,CDKN2D,EZH2,RB1,MIR29A,FAM107A,SOX2,KLF4,MIR10A,BTN2A2,CTDSP2,JADE1,RPL26,CRLF3,MDM2,MIR873,MIR133B,TP53,CDK2AP2,FBXO31,MIR15A,RPA2 |
| 1.248e-04 | -8.99 | MYH9 (myosin heavy chain 9) | protein interactions | 4627 | 663 | 229 | 19454 | 5460 |
PNMA3,FCHO2,MYL12A,TMPO,CDC5L,SSBP1,DSTN,SHC1,SNRNP70,USP15,USP2,COPS5,CSNK2A1,TPM3,KPNA2,PSMB10,CAPZA1,MAP1B,PALM2AKAP2,TCEA2,MRPS18B,CYBRD1,TFCP2,CAPZA2,ARPC3,NUPR1,KBTBD4,TP53,ACTR1A,DAPK3,RALA,PRKCE,ADRM1,CCDC42,PSMC5,MACROH2A1,ATP1A1,OAT,UBE2H,SORD,AKT1,CFL1,CFL2,ARHGAP21,KDM1A,HSPA5,BAP1,PML,TNFAIP1,RNF113A,RPA2,UBE2M,HEXIM1,ACACA,SPTBN1,NEK2,GABRA1,CFTR,DYNC1I2,FHIP1B,HSP90AB1,EED,CORO1C,AGR2,CBL,MAGOH,CIAO3,CCL11,DDRGK1,CTNNB1,PSMA1,KRAS,RUVBL1,DPM2,MYO1B,RUVBL2,TUBB4B,MTA2,OARD1,ARFGEF1,ISG15,PSMD6,PSMB6,APEX1,ESR2,EFHD2,MIDEAS,DYNLRB2,PRMT5,CREBBP,MYC,COPS7A,PSMD1,BTF3,CASP4,UFL1,PACSIN3,DDX39B,SPECC1L,HDAC5,HSPA8,EP300,EIF4B,PIH1D1,SSBP2,CDK9,PTP4A3,ACTA2,LDLR,PSMD7,CNN3,ATP5MG,HDAC6,HUWE1,VTA1,MRPS18C,FBXO25,PPP1R12A,FAF1,ZNF787,SEPTIN7,ACTR2,FBP1,PPIF,FCF1,NDN,TMOD3,NREP,YES1,RPL22,GNAI2,VIRMA,STUB1,CCNF,OPTN,TUBA1B,EIF4A3,CTTN,UBASH3B,UBE2I,MSN,IVNS1ABP,CDC73,NCKIPSD,AP2A1,STK38L,ATP5F1A,PPP1CC,USP14,TUFM,PIK3R2,SMC4,FBXW7,PIAS1,RPA3,MME,PRPF4,SIRT7,SYVN1,ARPC2,MTDH,JUP,METTL14,PICALM,STOM,JKAMP,TMOD1,RPS14,PSMC4,MYL12B,PIP5K1A,CDK7,COPS7B,SPTAN1,PPIA,SRSF10,OS9,WDR6,FOLR1,PHB1,COPS2,TRAF6,PSMD3,ATG9A,HNRNPA1,TNF,TRMO,RBBP7,TRIM37,GCA,AHCYL1,FLOT1,COPS4,HSPD1,MT3,UBE3A,EZH2,NGB,STX12,RAF1,ACTN4,PPP2R1A,OTUD6B,LGR4,ACTB,DYNLL1,GNG12,OVGP1,SNRPD2,AP2M1,YWHAZ,MYO6,BRCA1,SP1,HSP90AA1,DSN1,RAB11A,CUL3,NSFL1C,PSMC1,ARL6,UNC45A,CXCR4,PSMA3,ATP5PO,PSMB7,EMC9,MYL6,PPP1CB |
| 1.250e-04 | -8.99 | Toll-Like Receptors Cascades | REACTOME pathways | R-HSA-168898 | 153 | 70 | 10285 | 3229 |
PTPN11,MAP2K1,CTSB,MEF2C,PELI1,PPP2R1A,PELI3,UBB,TLR10,TLR4,UBA52,SKP1,PTPN4,CD36,TBK1,NFKBIA,MAP2K3,TLR1,TLR7,TLR5,LY96,TLR8,JUN,AGER,S100A8,IRAK4,NFKB1,DNM2,TANK,TLR9,FBXW11,ELK1,CREB1,DUSP6,S100B,TLR6,TAB1,FOS,UBE2D3,RPS27A,SARM1,DUSP3,CTSK,TRAF6,HMGB1,BIRC2,UBE2D1,IKBKB,TLR2,TICAM2,MYD88,HSP90B1,CD14,IRF7,UBE2V1,TICAM1,PPP2CB,DHX9,CNPY3,MEF2A,MAPKAPK3,TLR3,MAP2K6,TAB2,ATF1,NFKBIB,UBE2N,MAPK10,TIRAP,IRF3 |
| 1.252e-04 | -8.99 | NEK2 (NIMA related kinase 2) | protein interactions | 4751 | 126 | 55 | 19454 | 5460 |
HSP90AB1,CHGA,FUNDC2,FZR1,CORO1C,CDC23,BECN1,CTNNB1,TPM3,GAPDH,NDC80,CDC26,HNRNPDL,CAPZA1,HNRNPK,THRAP3,HNRNPF,SEMG2,RUVBL2,TRIM21,HNRNPA2B1,PPP1R12A,PSMC3,DTD1,CAPZA2,EEF2,EEF1A1,TCEAL7,MAD2L1,CDC20,SMURF1,EIF4A2,PRDX2,TMOD3,ANAPC2,CALML5,TRIM27,ANAPC4,PPP1CC,ANAPC15,CDC16,MYC,RNF41,HSPA5,CDSN,FBXW7,PPP1R2,HSPA8,ANAPC16,RPLP0,JUP,PPP1CB,NEK2,TANK,PSMC4 |
| 1.267e-04 | -8.97 | CDK3 (cyclin dependent kinase 3) | protein interactions | 1018 | 112 | 50 | 19454 | 5460 |
CKS2,HEXIM1,CDK1,CCNA2,CDKN1A,MYH1,CCNH,PGRMC1,CCND1,SPDYE4,CCND3,SKP1,FOXP2,HSPA8,CCNI,MYH2,HSP90AA1,STN1,GMNN,RACGAP1,CCNB1,CDKN3,TAB1,PHKB,EIF2AK2,ZNF189,OTX2,CDK5R1,PPARA,ISG15,CDK4,CKS1B,B3GNT2,PAX6,TRIM63,IGF1R,CDK5,SNIP1,MAP1B,AKT2,YWHAB,CDKN1B,STK4,YWHAH,COPS5,SAV1,STK3,HSP90AB1,RB1,CDK6 |
| 1.267e-04 | -8.97 | THADA (THADA armadillo repeat containing) | protein interactions | 63892 | 112 | 50 | 19454 | 5460 |
OPRL1,ILVBL,PRNP,HNRNPL,KRT8,TES,SEC23A,IGBP1,ARL10,CD274,SIN3A,P2RY10,FAM174A,PDIA3,AHCYL1,CD80,EFNB1,CD83,CYB5B,AQP3,SIGLECL1,CA14,MGARP,TP53,TOP3B,COMTD1,APEX1,VIRMA,APLNR,CHRM4,LMBR1L,S1PR4,SCN2B,SRXN1,CCNF,TYROBP,CD226,GPR17,OPRM1,CUL3,STAU1,NPTN,NUBP2,VIPR1,CD40,CFTR,CDC42,HCST,FAM234A,ATG16L1 |
| 1.268e-04 | -8.97 | LRRTM2 (leucine rich repeat transmembrane neuronal 2) | protein interactions | 26045 | 18 | 13 | 19454 | 5460 |
TMEM38B,TOMM40,DDX39A,CNPY3,LGR4,ST7,DCAF4,TTI2,ACTA2,TNF,KCTD15,CNPY4,DAD1 |
| 1.269e-04 | -8.97 | NCBP3 (nuclear cap binding subunit 3) | protein interactions | 55421 | 146 | 62 | 19454 | 5460 |
SF3A1,PABPC5,ZC3H14,RPA2,LARP4B,HNRNPH3,TMEM184B,RPA3,DDX39B,RPL27,SNRPA,PNO1,EP300,COIL,AATF,CUL3,HNRNPC,SNRPB,FYTTD1,CHTOP,ELAVL2,THOC6,LSM14B,ALKBH5,ZNF330,EZH1,RSRC1,DAPK1,FBXO22,SRPK2,ESR2,RAF1,E2F4,SUPT5H,DDX39A,APOBEC3D,PAIP2B,EZH2,NUPR1,SNIP1,RPL31,MRPL52,ARGLU1,ZC3H11A,RTCB,SRSF7,NUP42,SRSF4,POLDIP3,IFI16,RPL6,API5,TRA2A,SNRNP70,THOC2,ALYREF,HP1BP3,PAIP1,THOC1,AKAP17A,NCBP2,CEP19 |
| 1.277e-04 | -8.97 | EIF3M (eukaryotic translation initiation factor 3 subunit M) | protein interactions | 10480 | 175 | 72 | 19454 | 5460 |
PSPC1,OPTN,CCNF,METAP2,CMTR1,VPS72,EIF3K,RPL19,VIRMA,ESR2,EIF4A2,TENT5C,PSMD1,USP14,MYC,KCNJ2,MAPRE1,UBE2H,EIF3G,BRCA1,HSPA8,RAB5A,EP300,CFDP1,RPA3,EIF4E,G3BP2,EIF1B,NF2,RPL4,EIF3J,CFTR,ATG16L1,HEXIM1,EIF4B,ACACA,RPA2,SRP14,FBXO32,UBE2N,RBM42,HMG20A,HNRNPL,FZR1,RPS16,PRNP,CSNK2A1,EIF3D,WWP2,MED4,DRG1,HSPB1,RAB27A,ABCE1,MEPCE,PSMD12,EIF3E,AHCYL1,COPS4,SSRP1,G3BP1,HUWE1,EIF4EBP2,TGFBR2,TP53,RPS11,GPBP1L1,SRP72,SART3,RPN1,PNMA2,CHMP4C |
| 1.278e-04 | -8.96 | GLUTATHIONE_PEROXID_1 | prosite domains | PS00460 | 7 | 7 | 12186 | 3388 |
GPX4,GPX5,GPX3,GPX7,GPX6,GPX2,GPX1 |
| 1.281e-04 | -8.96 | respiratory electron transport chain | biological process | GO:0022904 | 102 | 48 | 18204 | 5365 |
COX7B,IMMP2L,UQCC3,COX4I2,UQCRH,COX6A2,NDUFS2,NDUFB6,ETFRF1,NDUFV2,SOD2,UQCRC1,COX6B1,NDUFA1,NDUFS8,NDUFB10,UQCR11,NDUFAB1,NDUFA12,NDUFA5,NDUFB7,GPD2,SDHAF2,UQCRC2,NDUFB4,CYC1,ETFB,COX5A,NDUFB5,TAFAZZIN,COX8A,NDUFA4,NDUFS3,SDHC,NDUFS6,SLC25A12,NDUFC2,COX7B2,UQCRQ,SDHB,COX4I1,VPS54,NDUFA2,SLC25A51,COX6C,NDUFB8,ETFA,COX7A1 |
| 1.285e-04 | -8.96 | RBM25 (RNA binding motif protein 25) | protein interactions | 58517 | 304 | 115 | 19454 | 5460 |
LMNB1,RIT1,MYC,CFAP20,SFN,PRPF31,SNRPB,DRAP1,SNRPB2,ESR2,CPSF1,TACO1,VPS72,SF3B4,RPL37A,MAP2K1,MFAP1,NUFIP2,UFL1,STAU1,ATP6V1G2,SAP18,SNRPA,DDX39B,UPF3B,HDAC5,SF3B1,EP300,DDX23,SKIC8,ANKRD50,HSPB1,PRPF19,IFI16,ZCCHC10,TRA2A,DDRGK1,SNRPA1,PEG10,SRSF10,WIF1,FOLR1,SRSF1,EED,SKA3,CHMP4C,SMARCB1,B3GNT2,RAF1,E2F4,NCSTN,ISG15,LGR4,MSX2,TRIM37,FAM76B,MYO1B,SRSF7,BAG2,MECP2,RC3H2,UBE2H,VPS39,AR,IFI6,ADRM1,PPP1R10,DEK,PSPC1,CTTN,ENO1,SYT2,GSK3A,UBE2I,TOX4,RPA2,OXSR1,ZNF574,HECTD1,SF3A1,CFTR,NUCKS1,RBM23,RPA3,SIRT7,TCEA1,RNF113A,SNRNP70,BRD3,USP15,MOV10,NFKB1,PPIL4,FZR1,RPS16,NKAP,TOP1,CDK9,RCHY1,DDX42,RNF8,TAF2,NUPR1,H2AJ,RPSA,MAP1LC3B,ACTR1A,VRK1,MEPCE,MSH6,SMN1,PPP1R12A,SNIP1,SEPTIN7,EMC2 |
| 1.289e-04 | -8.96 | AP2M1 (adaptor related protein complex 2 subunit mu 1) | protein interactions | 1173 | 403 | 147 | 19454 | 5460 |
BAP1,DVL2,RPA3,MTDH,MEA1,ABCC2,ATG16L1,SPTBN1,KCNJ11,CFTR,RPA2,FGFR1,PICALM,HEXIM1,RARS1,ACACA,CCNF,TUBA1B,HEXIM2,CSNK2B,RHOJ,SLC25A4,SFRP4,RPL22,MAT2A,PRKACB,IFNAR1,NRP1,STK11,EPHA2,AP2A1,UBE2H,STX8,EIF1AD,TSSC4,L1CAM,TNKS2,CTNND1,RIGI,KBTBD4,TNRC6C,ZNF581,CD2BP2,NECAP2,EEF1A1,MAP1LC3B,CTLA4,NECAP1,CAPZA2,AP1S2,FURIN,NUPR1,SGIP1,HRAS,FAM199X,TES,TNKS,PLEKHF2,NKAP,FCHO2,NAA11,G6PD,TMA16,HDAC6,LAMP3,GAPDH,SHC1,NOS1AP,TIAM1,MAP4,USP15,BMPR1A,DDX39B,NKAPD1,SPECC1L,CRY1,HSPA8,EP300,FXR2,UFL1,ADRB2,STAU1,RNF11,STX7,PRR13,PAK2,LMBRD2,MFAP1,RAN,ATXN1L,AP2M1,AP1G2,ACTB,TUBB,MAT2B,ACAP2,KBTBD6,MYC,CUL2,CUL3,CHRDL1,LAMTOR1,MYO6,RHOB,SLC25A5,MAGED4B,HNRNPA2B1,PCNA,CCDC32,RUVBL2,KRAS,RPS27A,MAGEC2,UTP25,ARFGAP1,RAF1,PTS,TUBA1A,ISG15,OTUD6B,SOX2,TUBB4B,EZH2,GPBP1L1,AP2S1,CORO1C,MAP1LC3A,DPPA2,OCRL,MPP1,RHOH,PRPF18,KIAA0232,ATG9A,LAMP2,ZCCHC10,XPO1,INSYN1,DDRGK1,TBC1D5,CTNNB1,AGR2,MED4,AHSA1,AQP4,BCL2L1,LHX2 |
| 1.297e-04 | -8.95 | ANXA7 (annexin A7) | protein interactions | 310 | 178 | 73 | 19454 | 5460 |
PDHB,SRI,ADAMTS10,RPA3,CSTB,HSPA8,PRKCB,RPA2,ATP5PO,PRKCA,MED31,PAAF1,CTSB,ATP5F1B,TENT5C,RBBP4,FBXO22,ACTB,LRIF1,DDAH2,ESR2,SRC,CCNF,INPP5K,CCDC90B,TMSB4X,ALG2,TMEM108,CRMP1,MYC,CREBBP,TAF5L,TIA1,ZBTB16,G3BP1,DYNC1I1,S100A10,DMPK,PSMB10,FAF1,KLHL23,ERG28,CPNE2,PIR,PLD3,CD14,TP53,KIF1C,CDK4,SOX2,EEF1A1,MAP1LC3B,TUBA1A,HNRNPL,PRNP,SUMO3,PPIA,CCT7,HRAS,ANXA4,ATP6V1A,UBE2D1,CBL,RPS2,MOV10,TLE1,EDEM1,FAM20C,COPS5,MAP3K14,ACTL6B,LYPLAL1,GAPDH |
| 1.297e-04 | -8.95 | F2RL1 (F2R like trypsin receptor 1) | protein interactions | 2150 | 178 | 73 | 19454 | 5460 |
ZDHHC17,SLC18B1,RTN4,SCN1B,CXCR4,ATP2C1,TMX2,SLC32A1,OGFOD3,GOLGA5,STOM,LMNA,MORN4,CAPN1,SYNGR2,COQ8B,TNPO3,B4GAT1,SRC,YES1,B4GALT3,ARMC6,ATP5F1B,INTS12,QSER1,CTNNA1,LRP6,ATP1B3,ATP1A3,HMOX2,ATP5F1A,ARL6IP6,F2,TMED4,TSPAN17,RINT1,TMED1,ATP5PF,RUSF1,PSMC3,BIRC5,TSPAN3,CAPN2,KDELR1,UCK2,AQP3,TNPO2,YIPF3,TMBIM1,DDX39A,IPO8,HSDL2,ATP5PB,RAMP3,SLMAP,PRNP,PLG,XPO5,CD63,SLC43A2,SLC39A13,CNN3,CBL,TMEM70,SLC35A1,FAM241B,COPS5,ADCY2,CD81,ICAM2,ATP5MG,SYNJ2BP,MOV10 |
| 1.297e-04 | -8.95 | BOP1 (BOP1 ribosomal biogenesis factor) | protein interactions | 23246 | 178 | 73 | 19454 | 5460 |
PTEN,GTF2A1,SYT2,PRKRA,MTG1,EIF2AK2,FAU,CCNF,RPL22,SRPK2,ESR2,SMURF1,SNRNP40,RPL13A,RPL35,RPL7L1,BUB3,NDN,GORASP2,CUL3,RPL7A,MYC,DNAJB6,SNX5,FBXW11,RC3H2,ARPC2,RNF113A,NLE1,SIRT7,UGDH,RPA3,FTL,WDR55,STAU1,RPL4,NPM3,UFL1,NDUFAF3,SYK,RPLP0,RPA2,KRR1,SRP14,LYAR,NOP58,CAND1,DDRGK1,CSNK2A1,IFI16,TSNAX,H2AC4,CHCHD1,SNRNP70,DDX23,WDR12,RPS24,KLF10,RPL3,NEK9,RPL31,RPL17,HMGN4,RPS7,JUN,H1-3,AURKAIP1,TP53,RAF1,OTULIN,CHMP4C,CHAMP1,VPS33A |
| 1.301e-04 | -8.95 | MTFR1 (mitochondrial fission regulator 1) | protein interactions | 9650 | 66 | 33 | 19454 | 5460 |
MIA2,DDIT3,AKAP1,S100B,EXD2,TOMM20,PXMP2,FKBP8,GABBR1,HSCB,PHB2,FGL2,TOMM22,RANBP1,MTCH2,MTX2,CAPZA2,RMDN3,PTPN1,AIFM1,ENO1,ARL10,GNB1,ESR2,PLGRKT,MTM1,ACTB,MOV10,SLC25A46,MARCHF5,FIS1,HTRA2,DICER1 |
| 1.303e-04 | -8.95 | DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1) | protein interactions | 1780 | 101 | 46 | 19454 | 5460 |
CCT5,FBP1,ACTR1A,DISC1,CCT8,SEPTIN7,RUVBL1,DYNC1I1,SMN1,PFDN1,RPL28,PFDN5,BTF3L4,FKBP4,BECN1,RPL23,SPHK2,DNAJC7,DNM2,AIP,WDCP,TCP1,DYNC1I2,CCT7,DBT,PAFAH1B1,CDKN1A,DCTN4,ANXA7,EP300,TTC1,STAU1,YTHDF1,EIF4E,CUL3,EMILIN1,BTF3,BICD2,CCT2,PFDN6,HSP90AA1,PFDN2,PFDN4,STUB1,DYNLL1,DYNLT3 |
| 1.303e-04 | -8.95 | GSPT2 (G1 to S phase transition 2) | protein interactions | 23708 | 101 | 46 | 19454 | 5460 |
TRA2B,UFL1,STAU1,ATP6V1C1,SHMT1,RBMS2,ETF1,ADSS2,ZNF326,RPL26L1,PIH1D1,PAPSS2,CTTN,STAT1,IREB2,IDE,MYC,APOBEC3B,HNRNPC,CCT2,PIP4K2C,ELAVL2,ATP1A1,IGF2BP1,CASC3,UBE2H,PABPC1,ZC3H11A,THRAP3,SRSF12,KIF1C,MOB3C,SRSF1,RCHY1,PABPC1L,PAIP1,SNX2,SNX1,SRSF10,MOV10,ATG7,HDAC6,TRA2A,DDRGK1,APOBEC3F,MAGOH |
| 1.307e-04 | -8.94 | POLR2J (RNA polymerase II subunit J) | protein interactions | 5439 | 149 | 63 | 19454 | 5460 |
MRFAP1,RPAP3,CPNE2,FAM168A,TCEA2,PDRG1,SSRP1,KRAS,DNAAF10,SATB1,KCTD17,RPAP2,PSMB9,CD14,MED9,SNAPC5,SUPT5H,POLR2C,POLR2G,POLR2D,RPRD1A,GTF2B,POLR2L,POLR2I,TOP1,WWP2,MED4,MED27,MED21,MED29,ELOF1,SNRPA,TRIM52,POLR1H,AATF,OIP5,MED30,POLR1D,PIH1D1,SDCBP,RPRD1B,WWP1,GPN2,POLR3B,POLR2F,INTS12,GTF2F1,GTF2F2,POLR3H,NFKBIA,POLR2B,SRC,MED17,NTAQ1,SNRPB,LMO2,MYC,CUL3,MED22,PFDN2,POLR1B,MED10,BRCA1 |
| 1.307e-04 | -8.94 | SIN3A (SIN3 transcription regulator family member A) | protein interactions | 25942 | 341 | 127 | 19454 | 5460 |
KLF1,SHPRH,BRMS1L,MXI1,KLF9,ETV6,H2AZ1,COQ8A,SMAD3,MYBL2,GATAD1,NR4A2,TAF9,CYP4V2,TLE1,COPS5,CSNK2A1,H3C1,SEM1,PHF1,SMN1,MDC1,MAP1B,BHLHE40,KLF10,TGIF2,HINT1,NKX3-2,TFCP2,TOPORS,SH3GLB1,HBP1,TAB2,SAP30L,MTA3,PHF23,PHF13,TP53,H2AX,ING1,ZMYM3,VIRMA,ZNF330,HEY2,CAB39,ING2,MACROH2A1,PTEN,MECP2,SMARCA5,MORF4L1,RUNX1,NONO,AR,KDM1A,GTF2I,SMC4,FBXW7,MBD3,HSPA5,BCL6,DDX46,RPA3,PML,RNF113A,RPA2,SNAI2,HECTD1,SEC22B,SUMO2,PHB1,EED,IGBP1,COPS2,POU5F1,ZCCHC10,PFDN5,NT5C2,ZBTB16,RBBP7,S100A10,SATB1,AHCYL1,COX8A,PIR,TUBB4B,EZH2,RBPJ,SMARCB1,MTA2,ZNF263,MAX,ZNF704,E2F4,ISG15,SOX2,SAP30,GTF2E2,RBBP4,TSN,ESR2,PHF12,RAN,ZMYM2,PRMT5,DCAF4,SP1,HSP90AA1,ILK,MYC,ACO2,IKZF2,SMARCE1,BRMS1,CPSF2,TGIF2LX,ZBTB5,SAP18,HDAC5,HSPA8,RLIM,CTBP1,MXD1,LACC1,ACTL6A,NOTCH2,TOM1L2 |
| 1.307e-04 | -8.94 | PLD1 (phospholipase D1) | protein interactions | 5337 | 129 | 56 | 19454 | 5460 |
CFL1,RHEB,RAB11A,CFAP20,RAB2A,CSK,PEA15,RHOB,LAMTOR1,TMEM74,LURAP1,ARF1,VIRMA,ATP6AP2,SRC,ACTB,RALA,STXBP1,FAXC,CDC42,PIP5K1A,PRKCA,EIF2B3,RAB9A,PPM1G,DVL2,CXCR4,TEX264,FTL,SLC31A1,LAMP3,INSYN1,ANKMY2,RAB5C,ZCCHC10,LAMP2,BRD3,ASIC2,RHOG,RAC2,ARL11,RAB35,CAV1,EIF2B5,ARF6,DDX39A,TP53,GPT,RAF1,PLD3,ZRANB2,AHCYL1,PTGES3,KCTD17,S100A10,KRAS |
| 1.307e-04 | -8.94 | ALDH2 (aldehyde dehydrogenase 2 family member) | protein interactions | 217 | 129 | 56 | 19454 | 5460 |
YWHAH,YWHAG,MRPS26,YWHAB,CHCHD1,GATD3,SSBP1,COX4I1,ESD,NUP35,TOP1,SOX2,PPP2R1A,PGM1,RAF1,HEXA,SOD2,SLC25A20,RAD23B,SERPINA1,PDHA1,HINT2,ERG28,HSPD1,IMMP2L,HSPE1,TF,TUFM,AUH,MTG2,PMPCA,CUL3,LDHB,CRMP1,PFDN4,YWHAZ,CALML5,ACOX1,UQCRC2,LDHA,RPL13A,NEK7,RPE,SLC35F6,ATG16L1,MTRES1,LMNA,RPA2,HSPB2,GFM1,RPA3,EXD2,GRPEL1,IGSF21,HSCB,PHB2 |
| 1.308e-04 | -8.94 | CXCL17 (C-X-C motif chemokine ligand 17) | protein interactions | 284340 | 16 | 12 | 19454 | 5460 |
CCL8,CXCL10,CCL2,CXCL9,CXCL14,CCL21,CCL25,CCL5,CCL28,CXCL12,XCL1,CCL20 |
| 1.308e-04 | -8.94 | Atp5f1a (ATP synthase F1 subunit alpha) | protein interactions | 11946 | 16 | 12 | 19454 | 5460 |
ATP5PF,ATP5PB,CCNF,PTEN,ATP5F1E,ATP5IF1,YWHAZ,ATP5F1D,ATP5PO,ATP5F1B,ATP5PD,CHCHD3 |
| 1.331e-04 | -8.92 | BRIX1 (biogenesis of ribosomes BRX1) | protein interactions | 55299 | 292 | 111 | 19454 | 5460 |
DDX23,WDR12,RPL23,DRG1,MED4,RPL6,IFI16,DDRGK1,RPL7,LYAR,DYNC1I2,MRTO4,PHB1,FBXO32,RPL8,EED,CHMP4C,GLE1,SART3,RPL18,MAGEB10,RAF1,RPS7,MAK16,SOX2,ISG15,KRAS,H1-6,RPS4X,SRSF4,RPL28,PABPC1,PPAN,RPL31,RPS24,FTSJ3,RBBP8,LAMTOR1,CIRBP,RIT1,H1-1,NSA2,CUL3,MYC,RPL10,SURF2,RPS9,RPL37A,APOBEC3C,RND2,STAU1,NOP53,UFL1,COIL,H2AC4,CHCHD1,SNRNP70,RPL10A,NOL12,GRSF1,HDAC6,CAND1,RPS16,ZBTB2,RBM42,RCHY1,KRR1,RBM34,LLPH,NUPR1,SRP72,HBP1,ILF2,RPL15,H3C1,RPL17,RPS13,RPL3,RPL23A,RC3H2,MECP2,UBE2H,ATP1A1,RPL7A,PPP1CC,RPL26,RPL13A,ZNF622,SRPK2,RPL22,OPTN,PSPC1,PRKRA,FGFBP1,GRM2,METTL14,RPA2,MACROH2A2,RPLP0,UTP15,RPL4,DGCR8,NPM3,UTP23,AATF,SIRT7,NLE1,RPA3,RPL27,MTDH,RNF113A |
| 1.338e-04 | -8.92 | MED22 (mediator complex subunit 22) | protein interactions | 6837 | 82 | 39 | 19454 | 5460 |
SMAD1,RPAP2,MED30,SOX2,TP53,MED9,LIAS,ATG16L1,MED31,BIRC5,HGS,POLR2G,POLR2C,POLR2D,DCTN4,CDK8,MED23,MED13L,DCTN3,DCTN6,FBXW7,KRAS,MED11,AR,NTAQ1,FBXO7,ZCCHC10,SMAD2,MED4,MED29,MED27,MED21,MED10,CCNF,POLR2B,RPL35,POLR2I,MED17,MRPL50 |
| 1.339e-04 | -8.92 | TUBB4B (tubulin beta 4B class IVb) | protein interactions | 10383 | 523 | 185 | 19454 | 5460 |
FBXO25,TCP11L2,HUWE1,THRAP3,EMC2,RAB1A,FAF1,PPP1R12A,MAP2K3,CCT5,CDK9,DCUN1D1,SCG2,TES,AIFM1,EFNA3,SSX2IP,DNAJC7,TTL,HDAC6,CDC42SE2,SQSTM1,INPPL1,RPA3,WNT7A,HAUS2,DCTN4,ZMYM6,HSP90B1,GRM2,METTL14,CDK7,SH3BGRL,VIRMA,JUNB,PDCD5,CEP97,ZNF622,NDN,SLC25A4,PTEN,CCNF,CTNNA1,TUBA1B,TXNIP,FBXO7,USP14,AHCYL1,RAD21,TNF,GNL1,TRIM37,MORC2,HSPD1,OSTM1,PLD3,EZH2,DSTYK,RAF1,B3GNT2,EGLN3,RPL7,MAP1LC3A,COPS2,RPL8,FOLR1,PHB1,RPL23,CAMSAP2,FBXL4,UCHL3,TXNL1,PSMA3,HADHA,ISOC1,NCALD,TUBB,AP2M1,HSP90AA1,PFDN2,KLK5,PFDN4,PFDN6,FAS,BRCA1,CUL3,CUL2,MEPCE,NEDD8,MAP1B,PSME1,RNF8,TFCP2,ACTR1A,MGARP,ZMYM4,UBL4A,TP53,LMAN1,SLAIN2,CDC5L,CAND1,CD274,SSBP1,USP15,RPL10A,TUBG1,SHC1,CD81,COPS5,HSPA5,RNF113A,BAP1,HEXIM1,UBE2M,HECTD1,RPA2,TCP11L1,GABRA1,CDC42,CFTR,CDC20,SMURF1,TRAF1,DAPK1,PRKCE,MACROH2A1,UBE2H,SPOP,BICD2,RC3H2,TRIM23,RSPH1,SMARCA5,PFDN1,PSMA1,EPHA4,RUVBL1,CCT8,STMN2,TUBA1A,KIF2A,TNPO2,ELK1,HSP90AB1,CCT7,AFTPH,TCP1,SUMO2,DYNC1I2,MAGED2,SIN3A,SSR2,POU5F1,MGMT,CBL,YWHAB,AGR2,XPO1,CTNNB1,DDRGK1,NT5C2,PFDN5,DIRAS2,UFL1,PRCP,PHB2,HSPA8,HDAC5,DNAL4,JAKMIP1,PIH1D1,PAFAH1B1,POLR2B,ZMYM2,ZNHIT6,DLST,COP1,DNAJB6,CCT2,PSMD14,BTF3,MYC,TBCE,HNRNPC |
| 1.339e-04 | -8.92 | MTF1 (metal regulatory transcription factor 1) | protein interactions | 4520 | 115 | 51 | 19454 | 5460 |
RPS4X,AP1M1,RPL28,RPS13,NKRF,HNRNPA2B1,DHX9,RPL3,RPL23A,DNAJC2,RPS11,RPL15,RPS7,EEF1A1,RPL7,RPL35A,RPS16,DHX15,SRSF1,RPL8,LDLR,RPL10A,DRG1,PRPF19,HNRNPA1,RPL4,PHB2,ZC3H15,XRCC5,RPL27,EP300,DDX5,SF3B1,HSPA8,RPLP0,MATR3,ESR2,RPL10,VIRMA,RPL19,RPS3,RPS9,PRMT5,LMNB1,IGF2BP1,RPL7A,HNRNPC,HSPA14,CREBBP,SMARCA5,NONO |
| 1.340e-04 | -8.92 | regulation of endopeptidase activity | biological process | GO:0052548 | 282 | 112 | 18204 | 5365 |
MCL1,SERPINB6,SERPINB10,IFT57,HTRA2,RPS27L,ARL6IP5,PSME2,MIR21,DNAJB6,SFN,PPARG,IFI16,FURIN,SERPINB9,GAPDH,BCL2A1,PRELID1,SERPINA3,TIMP1,VEGFA,NCSTN,PMAIP1,PSMB9,CDKN2D,SERPINH1,SRC,HSPD1,BCL10,FAM162A,PSENEN,TIMP4,PDCD5,SERPINI1,FASLG,IFI6,SERPINA5,RNF34,KLF4,EPHA4,ACVR1C,TNFSF10,EFNA3,CST3,MIR15A,MMP9,DAPK1,SERPINA1,CLEC7A,SERPINB11,BAX,TIMP3,MYC,ANP32B,PSME1,NLRP3,FAS,MIR17,CSNK2A1,HSPE1,IGBP1,CTSD,MIRLET7B,FIS1,PAK2,CAAP1,MIR339,SEMG2,JAK2,MIR29C,BCL2L1,NLRP2,BAD,DAP,PIH1D1,CRADD,PSMA3,SIAH2,SPOCK1,TNFSF15,AIFM1,SERPIND1,AKT1,NLRP1,SOX2,HMGB1,MIR205,SYK,KHDC1,PYCARD,AGER,MIR152,S100A8,NKX3-1,MUL1,ROCK2,BOK,RAF1,SMAD3,MIR24-1,VSIR,TNF,APH1A,DPEP1,RPS3,EGLN3,GPX1,BIRC2,CYFIP2,LAMP3,BAK1,SERPINB1 |
| 1.342e-04 | -8.92 | H2AC20 (H2A clustered histone 20) | protein interactions | 8338 | 289 | 110 | 19454 | 5460 |
CD99L2,RAB39B,MRPL50,KRR1,SCG5,H2AZ1,USP15,BRD3,UPK1A,RPS2,H2AC4,SUV39H1,USP2,SMN1,RNF20,MEPCE,H3C1,RPL3,MAP1B,RNF8,SGIP1,TNNI3K,CAPZA2,UBE2B,GPX7,H2AX,DEK,VIRMA,IFI6,HPF1,MACROH2A1,PRKRA,LIG3,EIF2AK2,PELP1,RPS3,CCNF,MAPRE1,UBE2H,PIM2,MECP2,RPS17,H2BC9,MORF4L1,CXXC1,TOMM20,STK38,USP8,RPS15,FLCN,PRKCB,SIRT7,SLC2A3,BAP1,PPM1G,RAG1,RPLP0,RPL26L1,HEXIM1,STX17,TPT1,HMG20A,CETN2,COPS7B,RPS10,GATD3,USP46,HP1BP3,NRSN1,FOLR1,TNFSF13,HNRNPD,CBL,H2BC17,MSL2,SSRP1,GOLGA7,UBE2A,TRIM37,HMGN4,H1-6,RBBP7,SART3,CCR1,POLR2C,H2BC1,ANP32A,RPL19,RORB,RBBP4,USP16,PRMT5,PARP2,H1-1,SETD7,BRCA1,ZCRB1,LMNB1,RPS6KA4,BLOC1S5,RIOK2,MYC,FOXP2,CCDC86,CFDP1,EP300,HDAC5,LACC1,ELK4,RAB37 |
| 1.342e-04 | -8.92 | YTHDF1 (YTH N6-methyladenosine RNA binding protein F1) | protein interactions | 54915 | 289 | 110 | 19454 | 5460 |
SLC25A12,RPS16,TMED9,FZR1,LHFPL4,SYNCRIP,EEF1AKMT3,RPS2,KCNJ10,SNRNP70,GRSF1,MOV10,PRR32,MEPCE,CNOT7,DYNC1I1,TOLLIP,RPL3,MLC1,FAF1,SLC25A11,GLUL,FURIN,NHERF1,ACADSB,MGARP,TP53,RPSA,YTHDF2,TECR,CEP97,RPS20,ZMAT5,CDIPT,CCNF,RPS3,PSPC1,SMAP2,CTTN,IGF2BP1,UBE2H,BICD2,RC3H2,DNAJC8,CEP85,OIP5,RBM22,LSM12,RPA3,RPL26L1,SCLT1,RPA2,VPS4B,QRSL1,AGO1,CFTR,RBFOX2,CEP19,NUP35,RPS10,FUBP3,NQO1,CPEB1,XPO1,UBXN6,CNOT2,SAV1,ISX,PRELP,SAR1B,LASP1,G3BP1,ZC3H7A,FAM168A,RPL31,PABPC1,LSM14A,FAM136A,SOX2,NUP153,MSX2,RAF1,TOP3B,PPIL3,USP5,PRRC2A,RPL10,ESR2,RPL19,SF3B4,FHIT,SERPINH1,DCAF4,MYC,CUL3,G3BP2,CMAS,B9D2,FXR2,STAU1,AKAP1,MCRIP2,SNRPA,SLC25A3,TMEM184B,KCTD12,LARP4B,EHD1,KRTAP8-1,CDKN1A |
| 1.346e-04 | -8.91 | carbohydrate derivative metabolic process | biological process | GO:1901135 | 975 | 339 | 18204 | 5365 |
AKR1C2,HINT1,NDUFB4,AKR1C1,GNPDA2,GCNT3,NUDT16,GAPDH,AKR7A2,RRM1,B4GALT4,HACD1,EDEM3,BMPR2,HMGCS1,ATP5F1E,SAMHD1,AK3,FAR2,HEXB,CMPK1,SMUG1,RAN,BPNT2,ALG2,GNPDA1,ST3GAL5,SDHC,PDE9A,B4GALT3,SLC30A5,NDUFS6,MAN1A2,PIGK,C1GALT1C1,HS2ST1,LIPA,ST8SIA4,PGK1,ELOVL4,AK5,PIGY,NUDT7,MGAT1,NDUFB8,LYG2,PAPSS2,HS3ST3A1,STT3A,B4GALT6,GMPPB,APOBEC3H,FBXO44,MACROD1,GNPTG,PIGC,AGA,CHST10,ELOVL3,ABCC5,NUDT4,ATP5PB,GNAI3,ADK,CHST13,NDUFS2,GMPS,GALNT1,ST6GAL1,PGM1,TNFAIP6,OARD1,NDUFV2,DLST,PGAP4,CSGALNACT1,CHST1,EXT1,GXYLT2,NDUFAB1,NME1,NDUFB10,ACSS2,NT5C3A,LARGE1,ANGPT1,HSPA8,B3GALT1,ST3GAL4,COX11,CHPF2,ATP5MC3,MGAT4B,UGDH,SORD,ENO2,PDE4B,TMEM165,LEP,MPP1,CLPX,BMPR1B,NPPC,UGP2,CHI3L1,MGAT5B,ELOVL6,CBR4,UCK1,APOBEC3B,NUDT9,PDE2A,DCTD,B3GNT2,ATP5F1D,FUT9,EXTL2,NDUFB5,GUCY1B1,PIGA,HS3ST1,CACNB4,TYMS,NUDT3,OGG1,MGAT4A,ELOVL1,APOBEC3A,CHST2,GALNT12,PDHA1,TPST1,FAM20B,GANC,CSGALNACT2,ENTPD4,G6PD,ST8SIA5,FKTN,SDHB,PTHLH,POMT2,FUT8,EDEM2,CHST7,ACAT1,BPGM,UMPS,ACOT8,TMEM59,GALNT2,NT5C2,ERH,GALC,SHMT1,UCKL1,GPAA1,PPT1,GPAM,FA2H,GK2,PPAT,EPHA2,ARFGEF1,CERK,NME2,AKR1B1,ATP5MK,FBP1,GTPBP1,DPM2,NDUFA5,ITGB8,APOBEC3C,GFUS,DPAGT1,TYW3,ADSS2,GFPT1,GMDS,ALG5,ADCY3,ATP6V1A,DCAKD,DCTPP1,NDST3,EDNRA,AK2,ELOVL7,ACP6,CMAS,NUDT19,NME4,PIGW,NUS1,ST3GAL1,SLC35C1,GANAB,ACOT6,NDUFS3,NEU1,NUDT5,PRPSAP1,GUK1,MFN1,NDUFC2,MTAP,OGDHL,ATP5PO,APOBEC3F,AQP11,SRD5A3,B3GALNT1,DTYMK,B3GALT4,NUDT1,ST3GAL2,PSEN1,RAB23,CASK,STOML2,FBP2,DNAJC30,ACSL4,FITM2,TUSC3,SUCLG2,HACD2,NUDT18,MMUT,HEXA,NANP,BAX,NDUFB6,TYW5,ENPP4,NDST1,ABHD6,IER3,ABHD10,SLC25A1,APOBEC3G,PGAP3,G6PC3,NDUFS8,HS3ST5,HAS3,APOBEC3D,OVGP1,ATP5F1A,PNP,DLAT,OST4,HTR2A,ENO1,PMM2,FUT1,NDUFA12,PDE7A,GNPNAT1,GAL3ST4,SULT1B1,UST,NDUFB7,GNMT,UPRT,GPD2,GLYAT,UCK2,DAD1,CHPF,XXYLT1,EDEM1,GALNT17,B4GALT1,DNPH1,B3GALT2,ATP5MC1,AKR1A1,SLC25A10,GLCE,ADCY2,UGCG,BAD,DCK,ACACA,B4GALT7,DOLK,TECR,ATP5PF,ALG11,KIT,GXYLT1,ATP1B1,CYTL1,RPE,ATP1A2,NDUFA2,DLG1,CHST11,MVD,IGF1,UCP2,UQCC3,RPIA,PDE1A,CHST9,CRYL1,RPN1,ATP5MG,GK5,ST6GALNAC3,HYAL2,NPR2,ATP5F1B,NUDT2,B4GAT1,TMEM106A,PRPS1,ATP5PD,PGAP2,LDHA,NDUFA1,PDE8A,GAL3ST1,PXYLP1,ABHD14B,PGAM1,QNG1,IL1B,OLA1,UAP1,PDHB,GALNT4,MPDU1,SULT1A3,PFKFB2,FKRP,GPC1 |
| 1.346e-04 | -8.91 | Signal amplification | REACTOME pathways | R-HSA-392518 | 33 | 21 | 10285 | 3229 |
GNA11,GNG3,GNAI3,GNB1,P2RY12,GNG13,GNB4,GNA14,GNG10,GNG7,GNG5,P2RY1,GNG11,GNAQ,GNG2,GNAI2,GNG12,GNB3,GNGT2,SRC,MIR197 |
| 1.347e-04 | -8.91 | BGLT3 (beta globin locus transcript 3) | protein interactions | 103344929 | 74 | 36 | 19454 | 5460 |
HSP90B1,JUP,LMNA,RPN1,RPSA,CCT5,EEF2,FAF2,ACTN4,EEF1G,CSE1L,PHB2,HNRNPK,SSRP1,HSPA5,HNRNPA2B1,HSPD1,DHX9,PC,HSPA8,FKBP4,LMNB1,CCT2,CKB,HSP90AA1,TUFM,GAPDH,ATP5F1A,HNRNPA1,MATR3,ATP5F1B,HSP90AB1,CCT7,EIF4A3,PTEN,GANAB |
| 1.353e-04 | -8.91 | SRSF4 (serine and arginine rich splicing factor 4) | protein interactions | 6429 | 286 | 109 | 19454 | 5460 |
SRPK2,TRAF1,DYRK1A,SMURF1,NDN,UBE2I,EIF4A3,UBE2H,PPIG,RC3H2,PPP1CC,USP14,ZSCAN25,AATF,BRIX1,FBXW7,MRPL40,RPS15,DERL1,CLK1,SIRT7,BAP1,RBM23,RPL26L1,ZNF574,LMNA,CPSF4,ZBTB2,CDC5L,MRPL24,AKAP17A,DKC1,TMPO,CAND1,RPS16,KRR1,CDK12,CHCHD1,SNRNP70,ZMYND11,APOBEC3F,GRSF1,RIGI,TICAM1,MEPCE,MRPL22,RPS13,SRSF12,THRAP3,IMP4,PAK1IP1,HUWE1,SNIP1,NUPR1,MRPL51,HBP1,TOPORS,CD2BP2,MRPL47,MRPL11,TBK1,ESR2,CMTR1,ZNF22,NSA2,ZCRB1,FYTTD1,SNRPB,MRPL16,CUL3,SFN,NOP16,HNRNPC,MRPS7,ZDHHC17,STAU1,TRA2B,SRSF2,EP300,CCDC86,NKAPD1,SNRPA,NGRN,ZC3H14,MTX2,SRSF10,RPS10,HP1BP3,RBM5,SRSF1,CLK4,MAGOH,RSBN1L,DDX23,TRA2A,MRPL9,HNRNPA1,RIOX2,MRPS35,IFI16,GTF3C3,G3BP1,SRSF8,EWSR1,ARGLU1,CHMP4C,GLE1,SOX2,MAK16 |
| 1.360e-04 | -8.90 | TXNDC12 (thioredoxin domain containing 12) | protein interactions | 51060 | 132 | 57 | 19454 | 5460 |
AK2,TUBG1,FKBP4,DDRGK1,MZT2B,LAMTOR2,CAV1,PRNP,GATD3,COMT,CAMLG,MSRB3,ACADSB,HADH,H2AX,GLRX5,LYPLA1,FBP1,MX2,RIGI,SAR1B,ABHD10,MPST,RBBP7,GUK1,COA4,HINT1,RAB1A,COP1,FXN,UBE2H,AK3,MTPN,MYC,TXNRD2,CUL3,PMPCA,CTSB,TXN,SMU1,SGTA,CCNF,ENO1,CYB5R3,PIH1D1,CDC42,DET1,GABARAPL2,ATG16L1,ZDHHC17,HSPA5,UFL1,SRI,COX17,PEBP1,BAP1,TMEM106B |
| 1.360e-04 | -8.90 | EIF2A (eukaryotic translation initiation factor 2A) | protein interactions | 83939 | 132 | 57 | 19454 | 5460 |
SNRNP70,ATG7,MPG,UBXN6,TRMT61A,CCT7,RPS10,FZR1,RPL35A,RPS16,EIF2S1,PHB1,RPS23,EZH2,BZW2,RPS7,GTF2E2,B3GNT2,TOP3B,CCT5,E2F4,RPS13,PTGES3,G3BP1,RPS24,BAG2,RPS5,CHORDC1,SPOP,CCT2,CYP1A1,BICD2,PPP1CC,RPS29,MYC,ATF4,CDC20,APEX1,TUBB,PPM1M,EIF2S2,RPS20,CCNF,EIF2AK2,EIF3K,PIH1D1,RPA2,SNRNP27,ATG16L1,CAPN1,TUSC2,STAU1,HSPA8,DDX5,EP300,BAP1,RPA3 |
| 1.362e-04 | -8.90 | AKR1C3 (aldo-keto reductase family 1 member C3) | protein interactions | 8644 | 36 | 21 | 19454 | 5460 |
SIAH2,PGM1,HDAC6,ISG15,MORF4L1,UBE2W,PMM2,AKR1C1,RAF1,CSK,NQO1,MDH1,AGR2,NME2,NUDT19,GATD3,ZHX1,CMBL,LRIF1,CDK9,AKR1C2 |
| 1.362e-04 | -8.90 | F10 (coagulation factor X) | protein interactions | 2159 | 36 | 21 | 19454 | 5460 |
SFTPC,CHAMP1,SDF2L1,CAMP,SERPINA5,GGCX,PIP4P2,F2,PRKAB1,PROS1,F7,TMEM106A,TAB1,SERPINB6,PLG,TFPI,DNAJB9,MGST3,PIP4P1,F10,GAD2 |
| 1.362e-04 | -8.90 | PELI3 (pellino E3 ubiquitin protein ligase family member 3) | protein interactions | 246330 | 36 | 21 | 19454 | 5460 |
STUB1,UBE2N,DNAJB4,HSPA8,PELI1,KRAS,CAMK2G,TRIM63,TUBB,RUVBL1,IRAK4,CCT7,RIGI,ADORA1,PIK3R3,TUBA1A,IQSEC1,MAP3K14,UBE2V1,CCT2,TRAF6 |
| 1.362e-04 | -8.90 | ZNF782 (zinc finger protein 782) | protein interactions | 158431 | 36 | 21 | 19454 | 5460 |
PCCB,UQCRC1,TOMM40,MTCH2,TOMM22,CYC1,PDHA1,NDUFS3,HADHA,ATP6V1A,COX4I1,NDUFA4,PHB1,UQCRC2,VDAC2,UQCRQ,NDUFS8,PHB2,PDHB,ATP5F1B,NDUFS2 |
| 1.372e-04 | -8.89 | PRPF31 (pre-mRNA processing factor 31) | protein interactions | 26121 | 363 | 134 | 19454 | 5460 |
PSMD14,YWHAZ,PPP1R16A,CUL3,ZNF250,MYC,USP13,SNRPB,PRPF31,ZNF668,SIAH1,SNRNP40,FBXO22,APEX1,SNRPB2,RPL10,ESR2,PNMA1,SNRPD1,SNRPD2,USP39,APOBEC3C,SUFU,ELK4,STAU1,UFL1,COIL,SNRPA,DDX39B,ZFP64,EP300,RAB5A,SF3B1,LBX1,DDX23,YWHAB,CDC23,AHSA1,TAF7,IFI16,MDFI,DDRGK1,XPO1,HNRNPA1,SNRPA1,SNRPD3,LSM5,C1QTNF1,CACYBP,PNMA2,SNRPE,TAF10,RHOBTB1,OTULIN,SART3,MAX,RUVBL1,KRAS,RAD21,SSRP1,UTP25,CDCA7L,RINT1,RPL31,RPS24,PICK1,RUVBL2,ZNHIT3,TXNIP,TRIM23,LSM6,BICD2,UBE2H,NCKIPSD,CEP70,GPRASP3,FBXO7,JAKMIP2,ZNF622,VIRMA,SMURF1,LURAP1,ZNF330,PELP1,TRIM27,LSM2,PAK5,RPA2,TFIP11,UBE2M,SNRPN,SF3A1,CDK7,HSPA5,LDOC1,PRPF4,BAP1,DVL2,RPA3,SQSTM1,PPIH,CCDC106,HNRNPH2,SNRNP70,ZNF473,USP15,SSX2IP,KPNA1,LSM3,ZNF24,EMC4,COPS5,PNMA3,TOP1,FZR1,RBM42,TMCC2,CDR2L,UBE2N,KBTBD4,UBL4A,EXOSC8,CD2BP2,RPAP2,HNRNPK,KPNA2,LSM4,CTNNBL1,EIF3E,SNRPG,SMN1,STX11,OLA1,MEPCE |
| 1.373e-04 | -8.89 | DNAJC25 (DnaJ heat shock protein family (Hsp40) member C25) | protein interactions | 548645 | 280 | 107 | 19454 | 5460 |
STX8,NSDHL,RPL3,STX18,TMX3,EMC2,SRPRB,FKBP8,PRDX4,CCDC47,PREB,LBR,RPL15,TFRC,SURF4,PTPN1,SRPRA,UBE2G2,CAMLG,DNAJC1,ARL6IP5,LMAN1,TMPO,TMEM199,DHRS7,EMC4,HM13,ELOC,POR,ESYT1,RPL10A,OSBPL8,PPM1G,RPL27,TEX264,FADS2,RAB29,MTDH,RTN4,YKT6,RPL4,TMEM209,RABL3,SEC22B,ARHGAP1,ST7,LMNA,SSR1,USE1,SLC12A2,RPLP0,LEMD3,GANAB,RPL13A,DHRS13,SEC63,C9orf72,RPL7A,HMOX2,RINT1,SCD5,EMC8,RETREG1,STBD1,MACO1,EMC10,STIM1,RPN1,PTRH2,ZRANB2,TAPT1,PLD3,RPL18,RPL8,RPL9,GJA1,RPLP2,STX5,COCH,RPL7,SLMAP,OS9,RPL6,BABAM1,PTDSS1,EMC6,DDRGK1,DEGS1,CDK5RAP3,HAX1,HADHA,EMC1,GOSR2,NOTCH2,PGRMC1,TOR1AIP2,VAPB,EMC9,FAM177A1,SEC61B,REEP4,ATP6AP2,VEZT,RPS29,SPCS3,LMNB1,SCFD1 |
| 1.373e-04 | -8.89 | SMC2 (structural maintenance of chromosomes 2) | protein interactions | 10592 | 280 | 107 | 19454 | 5460 |
KPNA2,MSH6,VTA1,MEPCE,HAPSTR1,CAPZA2,DISC1,PSMC3,PHF23,COMTD1,ACTR1A,FZR1,CDC5L,PTP4A3,CDK9,EEF1AKMT3,H2AZ1,CD274,NLRP1,USP15,SMC4,IRF3,BAP1,DVL2,RPA3,FGFR1,RPA2,DCTN4,HECTD1,ACACA,UBE2M,HEXIM1,ATG16L1,PSMC4,CDC42,FAXC,ADRM1,VIRMA,TUBA1B,CCNF,PTEN,SRP54,PSMC5,PHAX,TXNIP,RIC3,UBE2H,SUB1,SMARCA5,NCAPG2,RUVBL1,SEMA4C,KRAS,RBBP7,AHCYL1,RAD21,ACTR1B,RUVBL2,EZH2,MOB3C,MTA2,IFT22,B3GNT2,PPP2R1A,TUBA1A,SOX2,CCAR2,SUMO2,EGLN3,PHB1,DNM2,SIN3A,SPINT2,DROSHA,FAM174A,PSMD3,DDRGK1,STAU1,ABCC5,TRIM52,PSMC1,CXCR4,EP300,STK26,HSPA8,SDC2,FOXS1,BET1,RFXANK,SYNE4,TRIM29,RBBP4,BMP1,MATR3,ESR2,MAD2L2,DPEP1,NFKBIA,FOXP3,PRMT5,RIT1,CUL3,MYC,CASP4,MCM4,PSMD1,BTF3 |
| 1.387e-04 | -8.88 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043281 | 165 | 71 | 18204 | 5365 |
CTSD,HSPE1,RPS27L,IGBP1,ARL6IP5,CAAP1,SFN,MIRLET7B,DNAJB6,PPARG,FIS1,PAK2,NLRP3,IFT57,FAS,ANP32B,MCL1,HTRA2,MIR17,CSNK2A1,BAD,DAP,NLRP2,PMAIP1,CDKN2D,CRADD,VEGFA,PIH1D1,BCL2A1,BCL2L1,JAK2,PYCARD,KHDC1,RNF34,FASLG,IFI6,KLF4,NKX3-1,S100A8,TNFSF15,SRC,HSPD1,AKT1,BCL10,AIFM1,SIAH2,HMGB1,PDCD5,SYK,FAM162A,SOX2,NLRP1,LAMP3,DAPK1,MMP9,GPX1,EGLN3,RPS3,MIR15A,BAX,MYC,CLEC7A,BAK1,SMAD3,RAF1,BOK,MUL1,DPEP1,ACVR1C,TNFSF10,TNF |
| 1.391e-04 | -8.88 | USP10 (ubiquitin specific peptidase 10) | protein interactions | 9100 | 274 | 105 | 19454 | 5460 |
KLF4,RARS1,SNAI2,GRM2,METTL14,RPA2,CFTR,CCND1,SPTBN1,HSPA5,FBXW7,RNF113A,SQSTM1,PGK1,PML,RPA3,MAPRE1,IGF2BP1,RC3H2,SPOP,EIF3G,AR,AKT1,SNX3,PTEN,RPS20,EIF2S2,ENO1,METAP2,OPTN,CCNF,PSPC1,NUPR1,SRP72,MAP1LC3B,TP53,YTHDF2,DHX9,BACE1,USP15,MAP4,ID1,SNRNP70,SMAD4,HDAC6,EDEM1,KARS1,CD36,CDC5L,MDM2,RBM42,CGAS,RPS16,FZR1,LDLR,AIFM1,NUFIP2,LARP4B,USP39,SOX21,TANK,G3BP2,SLC18B1,STAU1,YTHDF1,UFL1,FXR2,HSPA8,SF3B1,LMNB1,CUL3,MYC,RPL10,TAB1,EIF4A2,SMU1,UBE2S,RPN1,TOP3B,RAF1,RFC2,RUVBL1,G3BP1,RTCB,TRIM11,RUVBL2,ZC3H7A,PCNA,PABPC1,LSM14A,DRG1,DDX1,TRAF6,CTNNB1,DDRGK1,EIF3D,WWP2,HMGA1,IFI16,CCAR2,SPTAN1,RPS10,HNRNPL,FAM98A,PHB1 |
| 1.392e-04 | -8.88 | lipopeptide binding | molecular function | GO:0071723 | 10 | 9 | 18094 | 5411 |
CD1A,TLR10,TLR1,TLR6,CD1C,CD1B,CD1E,TLR2,CD1D |
| 1.397e-04 | -8.88 | TP53 Regulates Metabolic Genes | REACTOME pathways | R-HSA-5628897 | 82 | 42 | 10285 | 3229 |
COX8A,YWHAG,SESN2,TXNRD1,LAMTOR2,PTEN,TXN,SFN,AKT2,RRAGA,COX4I1,TACO1,AKT3,AKT1,PRDX2,COX5A,SESN3,RHEB,LAMTOR3,GPX2,COX11,G6PD,PRDX1,YWHAB,LAMTOR1,DDIT4,PRKAG1,COX6B1,TP53,COX14,RRAGB,COX16,NDUFA4,COX7B,YWHAH,TNRC6C,AGO1,COX20,COX6C,MOV10,PRKAB1,YWHAZ |
| 1.397e-04 | -8.88 | TRIM27 (tripartite motif containing 27) | protein interactions | 5987 | 498 | 177 | 19454 | 5460 |
KCTD9,RPGRIP1L,BCCIP,PTPMT1,NIF3L1,TRIM23,UBE2E3,UBE2H,TRIM32,FAM193B,UBE2K,MRPL40,EIF4E,RBM23,RAB29,PML,TWNK,SDCBP,USE1,UBE2W,NEK2,FBXL19,CFTR,SLAIN2,UBE2N,CCDC92,KPNA1,USP15,TSNAX,USP2,TPM3,TCEA2,RBM41,DISC1,GFM2,TAB2,MSRB1,TP53,ZNF581,IKZF5,TRIM29,ESR2,TACO1,SURF2,NFKBIA,SCNM1,MIDEAS,GTF2F1,ARMC7,BAG3,SRSF2,UBE2D3,STAU1,SNRPA,LCA5,RAMAC,STK26,MTMR6,EHHADH,PSMB3,HMG20A,IKBKB,STAMBPL1,CDC23,UBE2E2,SPATA2,PSMA1,ARHGAP15,TRIM21,OAS1,TRIM11,NFKBIL1,SMARCB1,HGS,UBL5,MAGOHB,ABHD17A,HYCC1,EIF4A3,TMSB4X,TRIM27,PTEN,UBE2I,ATOSB,CCHCR1,STK38L,ZMYND19,NTAQ1,HYCC2,PPP1CC,GMNN,RACGAP1,PIAS1,MBD3,VPS28,UTP23,RPA3,SQSTM1,SHOC2,ATG16L1,FAM161A,TTLL10,KCTD15,PPP1R18,THOC1,MDM2,EIF4E2,PSMB1,RB1,EID1,MED21,DNAJC7,SMG9,ZNF688,ERCC3,FNDC11,KXD1,FOXC2,HDAC6,FASTKD5,EIF3E,TFPT,GARRE1,CPNE2,JOSD1,GNPDA2,ILF2,TBK1,SIAH1,TENT5C,CHCHD3,MAT2B,SNRPB2,MAD2L2,CDC7,HAPLN2,FAM83A,BRCA1,EXOC8,ILK,ZNF250,CUL3,PRPF31,UCHL3,NOP53,ATPAF2,PPARG,ADNP,IER2,NDE1,CDKN1A,LMO4,IFI27,PRPF18,RAB11B,ARHGAP25,MCOLN1,FXYD6,UBE2D1,RB1CC1,BABAM1,HR,BCL7C,EIF3D,ZBTB16,LASP1,TRIM37,AP1M1,UBE2A,ENKD1,MAGED4B,JAK1,FHL3,PPID,CHMP4C,STK16,CKS1B |
| 1.400e-04 | -8.87 | MED6 (mediator complex subunit 6) | protein interactions | 10001 | 93 | 43 | 19454 | 5460 |
KRAS,MED11,FBXW7,EGR1,SKP1,BCL6,NLE1,MED13L,MED23,CDK8,POLR2D,POLR2C,POLR2G,BIRC5,MED31,HECTD1,ATG16L1,VDR,MED9,FBXL19,MED30,RPAP2,SMAD1,FZR1,MED17,POLR2I,POLR2B,ESR2,CCNF,SMAD3,POLR2F,MED10,MED21,MED27,ATG3,STN1,MED29,MED4,SMAD2,RIT1,ZCCHC10,MED22,AR |
| 1.400e-04 | -8.87 | DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1) | protein interactions | 116092 | 93 | 43 | 19454 | 5460 |
HNRNPL,EIF2S1,ESR2,MIDEAS,POLR2F,H2AC4,PHOSPHO2,STK11,LHX2,HNF1B,MYC,CDC16,WWP2,XPO1,DNTTIP1,HDAC6,AR,KDM1A,KRAS,H3C1,TRIM63,ANP32B,MDC1,PAX6,RPA3,PPM1G,DNTT,PYM1,HAPSTR1,EWSR1,PICK1,RNF113A,RPA2,IRF8,KLF3,MFAP1,PAX9,E2F6,RAF1,EGR2,SOX2,CCNA2,SAP30 |
| 1.400e-04 | -8.87 | LCP1 (lymphocyte cytosolic protein 1) | protein interactions | 3936 | 93 | 43 | 19454 | 5460 |
KRAS,GCA,AIF1,RNF41,BAP1,RPA3,SIRT7,EGFL8,LCP1,MED23,PLS3,RPA2,PPARG,STX17,FKBP14,CCR1,HEXIM1,PPME1,CNDP2,RAD23B,ATG16L1,SSBP2,DDX39A,SOX2,CFTR,FTH1,ACTB,FBXO22,SMURF1,HRAS,LHFPL4,NRSN1,MSN,TTL,BICD2,CYP3A43,CNN3,AGPAT1,UBE2H,PRKX,PTDSS1,RUNX1,PDE4B |
| 1.404e-04 | -8.87 | RPL7L1 (ribosomal protein L7 like 1) | protein interactions | 285855 | 199 | 80 | 19454 | 5460 |
RPL35,RPL13A,MAD2L2,ESR2,RPL10,RPL19,RSL24D1,CCNF,LMBR1L,FGFBP1,PRKRA,RPL37A,RPS9,RIT1,DNAJB6,UBE2H,H1-1,MYC,CUL3,RPL7A,NOP16,GTF2I,UFL1,NPM3,DGCR8,RPL4,NOP53,STAU1,WDR55,G3BP2,MRPS7,FTL,RPA3,RPA2,GRM2,RPLP0,RPL26L1,ZNF574,MACROH2A2,RPS14,KLF12,CAND1,RPS10,SPPL3,CGAS,LYAR,ZBTB2,SURF6,RPL8,SRSF1,KRR1,WDR12,CHCHD1,SNRNP70,RPS2,BRD3,LHX2,BAZ1B,FGF1,CSNK2A1,DDRGK1,KRAS,RPS13,RPL28,RPL17,RIGI,RPL31,RPL3,RPL23A,CHMP4C,MAGEA4,RBM34,SART3,RPSA,MAGEB10,AURKAIP1,SOX2,RPL29,EGR2,RPL15 |
| 1.404e-04 | -8.87 | CAPN1 (calpain 1) | protein interactions | 823 | 199 | 80 | 19454 | 5460 |
RPA3,PSEN2,SIRT7,EP300,COL3A1,IL1A,STAU1,EIF4E,POLA2,GINS3,MARS1,SPTBN1,CFTR,RPA2,LDHAL6B,PAK2,STX17,MAP2K1,CNDP2,GNG12,NFKBIA,RAN,PRMT5,GAS2,MSN,LGALS3,MAT2B,PPP1R10,DES,ESR2,BCCIP,AKT1,MAT2A,NDUFB7,MYC,CUL3,BAG3,TUFM,LAMTOR1,UBE2H,TRIP4,ERO1A,RBBP7,FANCG,CTSC,RAD21,MVD,GPT,TP53,SOX2,NFE2L1,EEF2,FNTB,RP9,BZW2,NHERF1,CDK5R1,CAPN2,CD274,SYNCRIP,ATP6V1A,PTGDS,COG1,INA,ARF6,HNRNPL,SPTAN1,CD99L2,CAV1,G6PD,INPP4A,PDIA3,MARCHF5,EDEM1,GSTO1,AGR2,CBL,HNRNPD,BCL2L1,MAP4 |
| 1.404e-04 | -8.87 | MRPL47 (mitochondrial ribosomal protein L47) | protein interactions | 57129 | 199 | 80 | 19454 | 5460 |
MTG2,AUH,MYC,CUL3,PMPCA,MRPL16,RPL26,TUFM,RC3H2,UBE2H,HTRA2,TACO1,MRPL53,CCDC90B,MRPL13,MRPL23,LAMTOR3,RPL35,RPL13A,RPL19,RPL10,RPL27A,BET1,MRPL10,RBMS2,SMYD3,KLF12,MRPL12,MRPS18A,RPL26L1,MTRES1,NGRN,EXD2,MRPL34,GFM1,HSCB,MRPL17,NPM3,MRPL57,MRPL41,MRPL40,MRPL20,GRSF1,MTRF1,PDIA3,RPL6,MRPL9,HNRNPA1,MRPL18,RHOG,SNRNP70,CHCHD1,POU5F1,MRPS26,SSBP1,ACTA2,PRR3,FAHD1,GATD3,CGAS,MRPL50,MALSU1,MRPL24,MRPL11,AURKAIP1,APOBEC3D,METTL15,MRPL33,GFM2,MRPL49,RPL18,MRPL51,HSPD1,MRPL52,HINT2,FASTKD5,MRPL22,SRSF4,RPL17,IMMP2L |
| 1.405e-04 | -8.87 | CDK17 (cyclin dependent kinase 17) | protein interactions | 5128 | 61 | 31 | 19454 | 5460 |
EGLN3,CDK17,MANSC1,TMEM74,PPP2R5E,PPP2CB,PFDN2,EPHA2,CDKN1B,YWHAB,TDRD7,YWHAZ,YWHAH,XPO1,YWHAG,BAG3,PCCB,GAPDH,SUGP1,DPY30,DHPS,PPP2R5A,UNC45A,PPP2R3A,KRAS,S100B,HEXIM1,ACACA,CDK1,FEM1A,PNMA2 |
| 1.405e-04 | -8.87 | METTL18 (methyltransferase 18, RPL3 N3(tau)-histidine) | protein interactions | 92342 | 61 | 31 | 19454 | 5460 |
PPIH,RUVBL2,RPL3,PRPF4,CCT8,PHYHIP,S100B,RGS2,HSPA5,RUVBL1,KDM1A,CCL3,MND1,DDX39A,FNDC8,B3GALT4,MRPL49,SRP72,RARS1,SNRPD2,EIF3K,SRP14,CCT7,TMEM45B,TCP1,SNRPA1,YAE1,HSP90AA1,H1-10,SMAD4,CCT2 |
| 1.408e-04 | -8.87 | ADAR (adenosine deaminase RNA specific) | protein interactions | 103 | 268 | 103 | 19454 | 5460 |
ILF2,NUPR1,EEF1A1,TBK1,STRBP,TP53,MDC1,MSH6,TOLLIP,RPL3,DHX9,SNIP1,SNRNP70,TMPO,CDK9,CAND1,RPS16,THOC1,TOP1,AIFM1,TFIP11,RPA2,GRM2,METTL14,GTF3C4,RPS14,SPTBN1,SNRPN,PIAS1,AATF,FBXW7,RNASE1,EXOSC4,CLK1,SQSTM1,RPA3,BAP1,DVL2,UBE2H,DEPDC1B,AR,FOXA3,VIRMA,SRPK2,PRKRA,UBE2I,PTEN,CCNF,PSPC1,EIF2AK2,RBPJ,EZH2,AQP3,CHMP4C,PDHA1,SOX2,GTF2E2,RAF1,TRMT1L,UBE2A,HNRNPDL,SSRP1,RAD21,G3BP1,KRAS,RUVBL2,TOP2B,DROSHA,HNRNPA1,XPO1,DDRGK1,IFI16,DHX15,HNRNPL,TTC9C,SNRPA1,EED,THOC2,PHB1,PAK2,FOXS1,NEK7,G3BP2,UFL1,STAU1,HDAC5,EP300,SNRPA,XRCC5,ELAVL4,CDKL2,FTSJ3,FBXW11,BTF3,SNRPB,MYC,CUL3,ESR2,USP38,APEX1,MATR3,FOXP3,ZMYM2 |
| 1.409e-04 | -8.87 | CMAS (cytidine monophosphate N-acetylneuraminic acid synthetase) | protein interactions | 55907 | 118 | 52 | 19454 | 5460 |
ZCCHC10,MTMR12,GRSF1,DDRGK1,FIG4,GTF2E1,ANKRD49,EIF2B2,FAM98A,DNAJC1,MRPL11,INSIG2,NAA15,ATP5PB,EZH2,RAD1,HSPD1,CAMK2G,CHCHD2,H3C1,RPL28,MEPCE,MYC,RSPH1,MTPN,BTF3,BRCA1,UBE2H,DNAJC19,ZNHIT6,VPS72,PTEN,MED17,RNASEH1,RPL19,ESR2,MRPL12,GRM2,SOST,MED23,LMNA,RPA2,HEXIM1,RPA3,SNX33,ANAPC16,HSPA8,YTHDF1,RPL4,UFL1,DNAJC22,ATP6V1G1 |
| 1.409e-04 | -8.87 | WDR18 (WD repeat domain 18) | protein interactions | 57418 | 118 | 52 | 19454 | 5460 |
ESR2,PELP1,CCNF,SF3B6,EIF4A3,CSNK2B,MACROH2A1,NOA1,ATG3,LMNB1,BICD2,PFDN2,VMP1,UBE2H,RIT1,MYC,HNRNPC,CUL3,FBXO7,NPM3,SAP18,RPA3,SIRT7,EXOSC4,HSPA8,RNF113A,FOXS1,LMNA,RPA2,ANXA7,ATG16L1,DUSP22,CGAS,ZBTB2,CDC5L,H2AZ1,SRSF1,DRG1,IFI16,MOV10,GPRASP2,DDRGK1,KRAS,H1-6,RIGI,MDC1,SMN1,SNIP1,EZH2,IK,H2AX,NCSTN |
| 1.410e-04 | -8.87 | negative regulation of vascular endothelial growth factor production | biological process | GO:1904046 | 28 | 18 | 18204 | 5365 |
MIR205,MIR17,MIR20A,MIR106A,MIR373,MIR125A,MIR504,MIR195,MIR147A,MIR16-1,MIR34A,MIR361,MIR107,MIR378A,MIR140,MIR15A,MIR874,MIR146A |
| 1.411e-04 | -8.87 | MECOM (MDS1 and EVI1 complex locus) | protein interactions | 2122 | 357 | 132 | 19454 | 5460 |
SUCLG2,VIRMA,JUNB,COPE,PYGM,TRIM27,PSMC5,CSNK2B,RTRAF,MACROH2A1,UBE2I,ATP1A1,SMAD2,CALU,TUFM,SMARCA5,VPS39,MBD3,RPS15,PDHB,KDM1A,GTF2I,SMC4,FBXW7,OIP5,SQSTM1,MYH2,CYC1,LMNA,KLF12,PSMC4,RBFOX2,DKC1,CDC5L,SYNCRIP,SMAD3,AKAP8L,TSNAX,SMAD4,SMCHD1,CSNK2A1,SUV39H1,COX5A,MSH6,EIF3E,H3C1,KPNA2,MAP1B,SLC25A11,CBX3,ACTR2,EGR2,ACTR1A,LBR,SMAD1,ATP5PB,TP53,APEX1,DES,MATR3,RBBP4,SNRPD1,AP2M1,RRAS2,PHF21A,RAN,ELK3,RPS26,DNAJB6,CCT2,FTSJ3,RHEB,SMARCE1,SAMHD1,CREBBP,NIBAN2,PIK3R3,HNRNPAB,PSMC1,FXR2,NMRAL1,APPBP2,SF3B1,HADHA,XRCC5,CTBP1,MED23,ATP5PO,KLF3,ADNP,MYH1,LNX2,UQCRH,DHX15,NOP58,DYNC1I2,TCP1,MAGED2,HP1BP3,CBFB,THOC2,SRSF1,RB1CC1,TNNC2,HAX1,HSPB1,FOSL2,EIF3D,PRPF19,PSMD3,PRDX1,BAZ1B,RPS27A,AP1M1,SSRP1,HNRNPF,TRIM26,CHCHD2,RBBP7,TRIM37,RUVBL1,MYO1B,RUVBL2,TRIM11,BAG2,MTA2,RPN1,ZC4H2,TUBA1A,JUN,SOX2,RPS7 |
| 1.414e-04 | -8.86 | GPS1 (G protein pathway suppressor 1) | protein interactions | 2873 | 202 | 81 | 19454 | 5460 |
SRPK2,VIRMA,SNRNP40,RBBP4,DYNLL1,FBXO22,IP6K1,MACROH2A1,PHAX,PSMA6,TUBA1B,NFKBIA,LMBR1L,CPSF1,CCNF,FBXL14,UBE2H,RIT1,DTL,STK11,NCKIPSD,DCAF16,DCAF4,SENP8,SPOP,FBXO7,ATP5F1A,CUL2,CUL3,SMARCA5,COPS7A,HSPA5,SKP1,ASB3,SMC4,NF2,HADHA,EP300,APPBP2,HSPA8,FBXW4,RPA3,UBE2M,TBC1D17,RPA2,DET1,HSP90AB1,PRNP,COPS7B,DCUN1D1,COPS2,EIF4E2,WDR6,USP15,DCAF11,CRBN,FEM1B,COPS5,CNOT2,AP5S1,KLHL9,DCAF4L2,COPS4,APBB3,THRAP3,TRIM63,RUVBL1,FEM1C,NEDD8,ERO1A,KLHL24,MAP1B,RHOBTB1,GDI2,TUBB4B,IRF8,SAP30,TULP3,TNPO2,SOX2,TP53 |
| 1.421e-04 | -8.86 | SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) | protein interactions | 6595 | 320 | 120 | 19454 | 5460 |
CMBL,VIRMA,TMOD3,GMNN,AR,NONO,PSMB2,SMARCA5,UBE2H,CALU,MECP2,AOX1,TNFAIP1,SIRT7,BANF1,MBD3,CXXC1,SS18,HSPA5,KDM1A,HMGB1,SEC22B,PAX9,KLF4,P3H1,RPA2,SDCBP,RB1,COQ8A,MDM2,CDC5L,GTF2E1,ZMYND11,GAPDH,TPM3,IRF4,KPNA1,TAF9,BRD3,NR4A2,SNIP1,ZNF821,RIGI,H3C1,KPNA2,H2AX,EGR2,SOX9,ATP5PB,FBP1,RAP1A,CDK8,PRMT5,MCPH1,GTF2F1,RAN,CBX5,ESR2,STAT1,RBBP4,ACTB,SMARCE1,ZMAT3,IRF1,DRAP1,CPSF2,CREBBP,MYC,HNF1B,GCC1,MCM8,BRCA1,HSPA8,EP300,DDIT3,SMARCD3,HIRA,FOS,SAP18,SUPT4H1,ACTL6A,NUP62,ELF5,MYL6,KLF3,PPARG,EED,BRD9,SIN3A,DNM2,PHB1,PPIA,CNTROB,CHMP2A,NUP35,HNRNPL,BCL7C,NOL4,ACTL6B,MAPK4,WWP2,ZCCHC10,HAX1,HSPB1,LHX2,LBX1,PICK1,BCL7B,TOP2B,PAX6,RBBP7,RUVBL1,SOX2,ELF1,SAP30,SMARCB1,MTA2,EZH2,TMEM59L,PPFIA2 |
| 1.426e-04 | -8.86 | Mitotic Metaphase and Anaphase | REACTOME pathways | R-HSA-2555396 | 180 | 80 | 10285 | 3229 |
XPO1,PSMA6,MAD2L1,NUP107,PSMB2,PSMD1,MAPRE1,CENPP,KIF2A,PPP2CB,PSMD12,PSMC1,NDC80,ANAPC16,NUP37,B9D2,PSMD4,LMNB1,MIS12,ANAPC11,PPP1CC,RPS27A,PSMA1,PSMC3,SKA2,PTTG1,ANAPC4,CENPL,MIR484,PSMB9,SEM1,NUF2,ANAPC2,PSMD6,CDC23,PSMB4,ANAPC15,CENPM,PSME2,UBE2D1,PSMB3,PSMB6,PSMA2,BUB3,PPP2R5E,TMPO,PSMC5,PSMB11,PSMB10,PSMA5,BANF1,PSMA4,SPC24,PPP2R5A,PSMC4,PSMB5,PSMA3,LEMD3,BIRC5,CDC20,PSMB1,NDE1,SKA1,PSMD3,CDC16,PSMB7,UBB,VRK1,PPP2R1A,UBA52,LMNA,CDC26,SEC13,RAD21,PSMD14,PSMD7,PAFAH1B1,PSME1,PSMD10,DSN1 |
| 1.427e-04 | -8.85 | TIR_dom | interpro domains | IPR000157 | 26 | 17 | 18521 | 5414 |
TLR7,TLR10,SARM1,TLR4,TICAM2,PIK3AP1,TLR3,TICAM1,TLR1,IL1RAP,TLR9,TLR2,TIRAP,TLR6,TLR5,MYD88,TLR8 |
| 1.430e-04 | -8.85 | Mitochondrial translation termination | REACTOME pathways | R-HSA-5419276 | 87 | 44 | 10285 | 3229 |
MRPS7,MRPS23,MRPS33,GFM2,MRPL49,MRPS11,MRPL23,MRPS16,MRPS25,MRPL51,MRPS34,MRPS35,MRPS26,MRPL47,MRPS9,MRPL52,MRPS18B,MRPL33,MRPL36,MRPL41,MRPL50,MRPS17,MRPL10,MRPS28,MRPL34,MRPL20,MRPL57,MRPL24,MRPS18A,MRPS21,MRPL53,MRPL11,MRPL40,MRPL22,MRPL18,CHCHD1,AURKAIP1,KGD4,MRPS18C,MRPL9,MRPL12,MRPL16,MRPL13,MRPL17 |
| 1.432e-04 | -8.85 | MORF4L1 (mortality factor 4 like 1) | protein interactions | 10933 | 208 | 83 | 19454 | 5460 |
CDC5L,FZR1,MEAF6,GATAD1,RB1,SYNCRIP,H2AZ1,SIN3A,FBXO32,UBP1,CEP57L1,KPNA1,NAB2,BRD3,LHX2,MPG,AP5S1,VPS26A,DNAJB2,MSH6,SYN3,RBBP7,HNRNPK,KPNA2,RUVBL1,ZC3H7A,PICK1,RUVBL2,MRFAP1,FHL3,RBP2,MRFAP1L1,ZBTB26,NUPR1,DMAP1,TFCP2,EZH2,H2BC1,TUBA1A,THAP1,ELF1,TULP3,HINFP,MAX,E2F4,ROCK1,BTG3,RPL10,NMI,ACTB,TAB1,PHF12,TUBA1B,ELK3,VPS72,ICA1,ZMPSTE24,CHTOP,BRCA1,H2AZ2,KPNA6,DRAP1,RACGAP1,MYC,MORF4L1,TNNT2,PSMC1,FXR2,EP300,ARRDC3,RPA3,SH3GLB2,PLAC1,EPHX1,RPRD1B,LMNA,RPA2,VAPB,CTDSP1,MRPL12,ACTL6A,ING5,TPT1 |
| 1.437e-04 | -8.85 | membrane docking | biological process | GO:0022406 | 84 | 41 | 18204 | 5365 |
STX7,ICAM1,CHP1,EXOC2,CAV2,PPFIA3,STX5,KCNB1,STXBP1,VAPB,YKT6,VTI1B,GNAO1,VPS18,ROCK1,STX10,VMP1,AHCYL1,CPLX2,STX12,EXOC1,VAMP8,SNX3,EXOC3,STX1A,CFTR,STX6,PEX26,STX11,ESYT1,SNAP25,STX16,MSN,EXOC5,BVES,PSEN2,SNAP29,STX8,EXOC8,STX17,VAMP3 |
| 1.439e-04 | -8.85 | CDK6 (cyclin dependent kinase 6) | protein interactions | 1021 | 211 | 84 | 19454 | 5460 |
SSBP2,CCND1,UBE2W,SUMO1,CCNH,KDELR2,CDK7,CCNA2,CDKN1A,ZSCAN1,CDK1,RPA2,HEXIM1,MET,RTF2,ACACA,SOD1,RBM23,PML,CCNI,TERT,PSMA3,DDIT3,NF2,SRSF2,TRA2B,CCND3,AKT1,MYC,CDKN2D,RUNX1,FBXO7,AR,CALHM5,SMPD2,EPHA2,HSP90AA1,STK11,COP1,CASC3,UBE2H,H1-1,ZNF174,VGLL4,PPM1M,UBE2I,EGLN2,VIRMA,RAF1,TP53,CDK4,MAP1LC3B,MAP2K3,ZMYM3,EZH2,CDK5R1,NUPR1,MOB3C,SNIP1,CDKN2C,CDK5,PCNA,KLF10,SRSF7,CNOT7,SRSF12,ATG7,CTNNB1,TRA2A,PPM1B,BECN1,CDKN1B,UBE2N,RCHY1,EEF1AKMT3,SRSF1,RB1,CDK6,FZR1,TRIM15,GRM1,ELK1,PEG10,HSP90AB1 |
| 1.439e-04 | -8.85 | CHUK (component of inhibitor of nuclear factor kappa B kinase complex) | protein interactions | 1147 | 211 | 84 | 19454 | 5460 |
HECTD3,MRFAP1L1,MAP3K11,SMN1,SEMA4C,H3C1,TNF,DUSP1,TRAF2,TP53,E2F4,NLRP2,RNF8,DCUN1D5,TAB2,TFRC,UBE2N,EEF1AKMT3,PPP2CB,SMAD3,HSP90AB1,PRKCQ,LRRC14,EGLN3,MYL12A,MAP3K14,CTNNB1,SPATA2,GTF2E1,COPS5,XPO1,HNRNPA1,CSNK2A1,UBXN6,NFKB1,HSPB1,TRAF6,PPM1B,IKBKB,BCL10,EP300,TRIM22,PRKCB,CD40,RPL27,PEBP1,CLU,PIAS1,RNF11,CFTR,INSYN2A,CXCL8,TANK,CCND1,PRKCA,RPA2,PTEN,UBE2I,TRIM27,NFKBIA,EIF2AK2,TNFRSF1B,NFKBIB,CCNF,STUB1,SRPK2,TRAF1,SRC,PRKCE,MAP3K3,GGH,TRAF3IP2,PYCARD,CUL3,PTPN11,AKT1,RETSAT,MYC,CREBBP,TNFAIP3,SMAD2,HSP90AA1,CDC73,UBE2E3 |
| 1.441e-04 | -8.84 | PRRC2C (proline rich coiled-coil 2C) | protein interactions | 23215 | 253 | 98 | 19454 | 5460 |
DDRGK1,YWHAH,CPEB1,PPFIBP1,YWHAG,WWP2,GSTM3,CNOT2,HSPB1,DRG1,RB1CC1,PHB1,FUBP3,SRSF1,HSP90AB1,NUP35,CACYBP,TCP1,LGR4,ISG15,RAF1,B3GNT2,RPS11,EZH2,PLS3,BAG2,RABGGTB,ZC3H7A,LSM14A,PABPC1,HSPD1,HNRNPDL,CHCHD2,G3BP1,EMC8,SFN,MYC,RPL10,PRRC2A,TAX1BP1,EIF4A2,ATP5F1B,WDR77,EMC9,PPT1,LARP4B,PAK2,HSPA8,SNRPA,G3BP2,STAU1,YTHDF1,FXR2,GAPDH,CSNK2A1,ZNF24,MOV10,ENY2,SNRNP70,SYNCRIP,G6PD,CDK9,RBM42,RPS16,FZR1,MAP1LC3B,EEF1A1,TP53,YTHDF2,JPH4,CCT5,TBK1,HINFP,SRP72,RAB1A,SEM1,ERLEC1,UBE2H,MAPRE1,IGF2BP1,RC3H2,EIF3G,RPS20,SMAP2,CCNF,PSPC1,VIRMA,SRPK2,NDN,TXN,CFTR,CAPN1,ATG16L1,HAUS2,RNF113A,SIRT7,BAP1,AATF |
| 1.445e-04 | -8.84 | COQ8A (coenzyme Q8A) | protein interactions | 56997 | 214 | 85 | 19454 | 5460 |
VDAC1,CSE1L,G3BP1,CHCHD2,GTF3C3,NDUFA4,ATP5PF,MAP1B,SLC25A10,CLPB,SLC16A1,PDHA1,RBM34,NDUFS3,RPN1,GPD2,CYB5B,SH3GLB1,ATP5PB,RAF1,HNRNPL,MRPS23,ERLIN1,EGLN3,TMPO,ILVBL,ATP5PD,COQ8A,SIN3A,RPRM,ACSL4,STT3A,MAGED2,ESYT1,ADPRH,TUBG1,AHSA1,STOML2,RAB5C,MOV10,DDRGK1,ORMDL3,XPO1,CMTM6,MRPL41,SSR3,POLDIP2,CLU,G3BP2,NT5C3A,RPA3,RABAC1,ATP5PO,RPA2,FDFT1,TFIP11,PGRMC1,AGTRAP,COQ8B,ABHD5,UQCRC1,CDC42,CPT2,DYNLL1,MRPL23,CYB5R3,IRF2,CCNF,STX10,PTPMT1,MRPS16,ATP1B3,SMPD2,DESI2,REEP6,CALU,UBE2H,SERPINH1,ATP1A1,RAB11A,PMPCA,CUL3,RAB2A,DEPDC1B,MRPL16 |
| 1.446e-04 | -8.84 | Unfolded Protein Response (UPR) | REACTOME pathways | R-HSA-381119 | 92 | 46 | 10285 | 3229 |
HSPA5,EIF2S1,GSK3A,EXOSC3,ATF4,HSP90B1,PREB,GOSR2,GFPT1,ATF3,NFYB,SEC61G,SHC1,EDEM1,SSR1,XBP1,PLA2G4B,DDIT3,ADD1,SRPRA,DCP2,SEC61A1,CALR,SULT1A3,ARFGAP1,CTDSP2,PDIA6,CXCL8,SYVN1,LMNA,SRPRB,SEC62,EXOSC1,YIF1A,NFYA,SEC61A2,SEC61B,ZBTB17,SEC63,EXOSC8,CXXC1,CCL2,DNAJB9,EXOSC4,DNAJC3,FKBP14 |
| 1.446e-04 | -8.84 | Respiratory electron transport | REACTOME pathways | R-HSA-611105 | 92 | 46 | 10285 | 3229 |
COX20,UQCRC2,SDHC,COX6B1,UQCRC1,TMEM126B,NDUFB6,COX14,COX16,UQCRQ,NDUFC2,UQCR11,ETFB,NDUFA4,NDUFS6,NDUFB4,NDUFAF2,NDUFA5,NDUFV2,TACO1,COX4I1,COX5A,NDUFAB1,NDUFA12,NDUFS8,TIMMDC1,NDUFS3,NDUFA1,SDHB,COX6C,NDUFAF6,NDUFA2,COQ10B,NDUFAF4,COX7B,UQCRH,ETFA,COX11,NDUFB5,NDUFB8,COX8A,CYC1,NDUFB10,NDUFS2,NDUFAF3,NDUFB7 |
| 1.446e-04 | -8.84 | RNA destabilization | biological process | GO:0050779 | 182 | 77 | 18204 | 5365 |
MIR1-1,MIR145,MIR191,HNRNPD,ROCK1,MIR9-1,CNOT6L,MIR142,AGO1,PDE12,MIR135B,MIR223,CNOT2,MIR106B,MIR34B,MIR192,ROCK2,MIR24-1,MIR185,EXOSC8,MIR98,MIR130B,MIR211,MIR23A,MIR140,MIR26B,MIR190B,YTHDF1,CNOT8,MIR495,MIR340,MIR885,MOV10,MIR491,MIR16-1,YTHDF2,MIR195,MIR210,DXO,EXOSC3,MIR424,MIR137,MIR200C,CNOT7,RC3H2,MIR708,MIR204,MIR423,MIR181C,MIR125A,MIR212,MIRLET7B,MIR130A,MIRLET7C,MIR149,METTL14,MIR519D,MIR146A,CNOT6,MIR497,MIR96,MIR30B,MIR214,DCP2,MIR100,MIR193A,MIR20A,MIR320A,TNFRSF1B,MIR181D,MIR625,ALKBH5,MIR206,MIR342,FXR2,MIR373,MIR106A |
| 1.447e-04 | -8.84 | Toll Like Receptor 9 (TLR9) Cascade | REACTOME pathways | R-HSA-168138 | 97 | 48 | 10285 | 3229 |
SKP1,MAP2K3,TLR7,NFKBIA,MEF2C,MAP2K1,TLR4,UBA52,PELI1,PPP2R1A,UBB,PELI3,ELK1,CREB1,TAB1,FOS,S100B,DUSP6,IRAK4,NFKB1,LY96,TLR8,AGER,JUN,TLR9,FBXW11,IKBKB,TICAM2,DUSP3,TRAF6,HMGB1,CD14,MYD88,RPS27A,TAB2,ATF1,NFKBIB,MAPKAPK3,TLR3,MAP2K6,MAPK10,UBE2N,TICAM1,PPP2CB,IRF7,UBE2V1,MEF2A,DHX9 |
| 1.454e-04 | -8.84 | MAX (MYC associated factor X) | protein interactions | 4149 | 244 | 95 | 19454 | 5460 |
PSMD6,RPL35,VPS72,PHF21A,TFDP2,FBXW11,HSP90AA1,MYC,PRPF31,BRMS1,GABBR1,SKP1,UNC45A,HIRA,XRCC5,HADHA,YAF2,EP300,MXD1,ACTL6A,PPP1CB,MEAF6,HMG20A,NUF2,RPRD1A,SIN3A,PPP2CB,POU5F1,TAF7,XPO1,ACTL6B,KRAS,ASF1A,RUVBL1,RAD21,PCGF6,MORC2,SDHC,RUVBL2,EZH2,MAX,MED9,TUBA1A,PPP2R1A,JUN,SAP30,TULP3,ZBTB17,PELP1,METAP2,LIG3,UBN1,MACROH2A1,GLOD4,MECP2,ZNHIT3,PIP4K2C,CCHCR1,SMARCA5,MORF4L1,PPP1CC,KDM1A,OIP5,FBXW7,HSPB2,HNRNPH2,JUP,RPA2,CHMP1A,GOLGA5,GIT2,E2F6,FTH1,PLEKHF2,ARL6IP5,TOP1,BRMS1L,MXI1,KLF9,SMAD3,SSBP1,LDLR,SMAD4,CDK12,COPS5,CSNK2A1,THRAP3,TFPT,SNIP1,TCOF1,RING1,CBX3,MRPL36,DMAP1,SPRR1B |
| 1.454e-04 | -8.84 | HSPA4L (heat shock protein family A (Hsp70) member 4 like) | protein interactions | 22824 | 220 | 87 | 19454 | 5460 |
LMBR1L,TAGLN2,TCEAL1,STAT1,FBXO22,MCM3,NFYA,MYC,CUL3,GRB10,NTRK3,SP1,LMNB1,BRCA1,PSMD14,HSPA8,NUBP2,TTC1,EDEM3,KLC2,PIH1D1,FKBP14,KRT8,CBFB,PAIP1,OSBP,CPEB1,IFI16,VPS26A,PPP3CA,PPP1R11,CCAR1,TFG,KIF2A,METTL21A,CHMP4C,PDHA1,MSN,SGTA,PTEN,CCNF,STUB1,CREB1,DUSP10,DNAJC8,NAPA,UBE2H,CALU,RC3H2,TXNIP,DNAJC10,RPA3,BAP1,GRPEL1,TUSC2,HSPA5,PDHB,CFTR,HEXIM1,SCLT1,UBE2M,HECTD1,JUP,RPA2,FGFR1,CEBPG,SEC23A,FZR1,PRNP,CGAS,COPS5,DNAJB2,DNAJC7,H2AC4,DHX9,HINT1,TAGLN3,IGF1R,FAF1,NEDD8,HSPE1,TTC4,MAP2K3,TP53,MTCH2,APEH,DNAJC2 |
| 1.454e-04 | -8.84 | MTREX (Mtr4 exosome RNA helicase) | protein interactions | 23517 | 220 | 87 | 19454 | 5460 |
TOP1,CAND1,DBR1,HNRNPL,FZR1,DHX15,CDC5L,NCBP2,TRMT61A,RCHY1,EIF4E2,EED,SNRNP70,DROSHA,MPHOSPH6,YWHAB,ANKMY2,WWP2,IFI16,DIS3L,DDRGK1,YWHAH,COPS5,CSNK2A1,YWHAG,XPO1,CSE1L,KRAS,RAD21,MEPCE,PABPC1,RPL31,DHX9,RAB27A,EXOSC3,SKA3,TAF10,NUPR1,DOHH,MOB3C,RNF126,E2F4,DHX38,TP53,KBTBD4,EXOSC8,SOX2,PPP2R1A,SNRNP40,MATR3,EIF4A3,CCNF,TRMT6,CSNK2B,SNRPD2,RC3H2,YWHAZ,UBE2H,RIT1,RBM7,HSP90AA1,EXOSC1,SP1,FAM107A,CUL3,MYC,PPP1CC,AR,UFL1,NLE1,SIRT7,RPA3,SNRPA,MTDH,EP300,COMMD2,DDX5,C1D,SYVN1,EXOSC4,METTL14,RPA2,PALS2,CAPN1,SF3A1,SYK,ATG16L1 |
| 1.459e-04 | -8.83 | RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) | protein interactions | 58490 | 226 | 89 | 19454 | 5460 |
TOM1L1,POLR2B,ESR2,SURF2,POLR3B,POLR2F,MED10,MYO6,BRCA1,OSGEP,PFDN2,PFDN6,POLR1B,RIT1,MYC,LMO2,SNRPB,SRM,SNRPA,NMRAL1,EP300,PIH1D1,ACTL6A,SUMO2,HMG20A,WIF1,RPRD1A,POLR2L,WWP2,PFDN5,PPIB,KRAS,SSRP1,BCL7B,EWSR1,RPAP3,BAG2,POLR2D,POLR2C,TPD52,SUPT5H,HEXA,SPG21,TNPO2,CCNF,LIG3,POLR3H,PTEN,UBE2I,TRIM24,NIF3L1,HOXC4,STK11,CALU,MORF4L1,AR,PPP1CC,GRPEL1,POLR1H,SOD1,RPA3,RPRD1B,RPA2,HNRNPH3,DDIT4L,ARHGAP1,POLR1D,SNRNP27,RPL35A,POLR2I,TOP1,CXCL14,PSMB1,TES,RB1,CALR,KXD1,HUWE1,DNAAF10,PDRG1,PPP1R12A,ABCE1,ACTR2,POLR2G,PPME1,NUPR1,CENPM,TP53,RPAP2 |
| 1.461e-04 | -8.83 | TK1 (thymidine kinase 1) | protein interactions | 7083 | 232 | 91 | 19454 | 5460 |
CCDC90B,MAD2L2,LRIF1,ACTB,RBBP4,TRIM46,EIF4A2,ATP5F1B,DRAP1,DBH,CUL3,MYC,COP1,CRMP1,JADE1,HERC3,THOC3,BOLA2B,HSCB,CDKN1A,PIH1D1,MED31,CRYAB,ATP6V1A,SUMO3,MPP1,SNX1,SUMO2,ODC1,ACTL6B,WWP2,CRIP1,ACTR1B,KLHL23,DMPK,RUVBL1,ZBTB16,PTPN4,TUBA1A,ARFGAP1,AAMP,PLD3,EZH2,ALB,TMSB4X,SULT1A3,INPP5K,CCNF,DDAH2,CDC20,GPX1,UBE2H,ZBTB38,EIF3G,DVL2,RPA3,SEPTIN6,ADAMTS10,CFTR,PAAF1,CCND1,AGAP1,CARHSP1,RPA2,CDK1,ADD1,NKIRAS2,KCNMB2,FZR1,GAPDH,FAM20C,TLE1,TSPO,MOV10,RPS2,NEUROD2,MRFAP1,EDA2R,ERG28,KLHL24,PSME1,FAF1,DDR1,DYNC1I1,EEF1A1,MAMDC2,CDK4,TP53,ABHD4,PPP4C,MAGEA4 |
| 1.462e-04 | -8.83 | extrinsic component of cytoplasmic side of plasma membrane | cellular component | GO:0031234 | 47 | 26 | 19108 | 5553 |
GNGT2,TRAF3IP2,GNAQ,GNA11,GNG7,GNAZ,GNAI2,TIRAP,GNG13,GNB3,JAK1,DLG4,GNB1,GNG11,GNB4,TRAF6,GNG5,GNG3,GNAO1,GNAI3,JAK2,GNG10,GNA14,GNG2,GNG12,MYD88 |
| 1.475e-04 | -8.82 | Extension of Telomeres | REACTOME pathways | R-HSA-180786 | 31 | 20 | 10285 | 3229 |
RUVBL2,PCNA,FEN1,POLE3,TERT,PRIM2,RPA2,RFC4,POLD2,POLD4,RFC5,NHP2,RFC2,RPA3,RFC3,POLA2,DKC1,WRAP53,POLE4,RUVBL1 |
| 1.476e-04 | -8.82 | regulation of DNA-binding transcription factor activity | biological process | GO:0051090 | 371 | 142 | 18204 | 5365 |
PHB2,PRNP,KLF4,NEUROD2,MIR140,TRIM21,CD200,CD40LG,TRIM27,DDIT3,STK3,TLR4,COMMD6,PPP2CB,ID1,TRIM34,PSMA6,IL18,FOXP3,ADORA3,BCL10,RPS6KA4,RWDD3,MIR1-1,CLEC7A,IL6,PPIA,PYDC2,MIR15A,NUPR1,PRDX3,MIR133B,G3BP2,ZC4H2,TRIM68,LRRC14,WWP2,UFL1,FZD4,PPARG,CCDC22,TRIM26,CTNNBIP1,MIR21,TCEAL7,SFRP4,TLR9,TRIM52,GFI1,NR0B1,BRMS1,MYD88,JUP,PRKCQ,SUFU,BUD31,RGCC,ESR2,FAF1,FZD6,TAX1BP1,ANXA4,MAD2L2,RBCK1,MAVS,IKBKB,MTPN,TRIM15,FOXS1,SMARCB1,NFKBIL1,SLCO3A1,S100A8,PROX1,BHLHE40,TNFSF18,PYCARD,MTDH,AGER,IL1RAP,TRIM5,UBE2V1,SYK,TRIM37,CLU,DHX9,AKT1,IL1B,CD40,OTULIN,TRAF1,TNFAIP3,WNT2,TRIM32,TRAF2,TRIM62,TMIGD3,MIR9-1,TRIM8,RPS3,EDA2R,TRIM6,TFRC,DDRGK1,EP300,NFKBIA,TNF,CRTC2,SMAD3,CHP1,MIR101-1,MIR144,XCL1,IL10,AR,UBE2N,TRIB1,NEUROG2,TRIM22,CREBZF,NLRP3,TRAF6,TLR2,EIF2AK2,CYP1B1,KIT,CEBPG,CDK5RAP3,DVL2,PRMT2,HDAC5,MIR16-1,DAP,COPS5,SUMO1,RB1,PSMD10,PTEN,LRP6,TIRAP,KDM1A,MDFI |
| 1.478e-04 | -8.82 | EIF3J (eukaryotic translation initiation factor 3 subunit J) | protein interactions | 8669 | 121 | 53 | 19454 | 5460 |
EIF3J,RPA2,EMC9,EIF4B,UBE2M,CSNK1A1,TPD52L1,RPA3,BAP1,XRCC5,HSPA8,RAB5A,RNF113A,EP300,TTC1,NF2,G3BP2,SFN,EIF3G,TADA3,CYP1A1,CCNF,PSPC1,ZNF174,EIF3K,CSNK2B,MED17,SIAH1,JUNB,B3GNT2,GTF2E2,MSX2,UBR7,NFE2L2,RPS11,SRP72,ABCE1,RPS24,G3BP1,EIF3E,CALR,WWP2,CSNK2A1,CTNNB1,EIF3D,SMAD4,DRG1,RPS16,IFRD2,SPPL3,TOP1,RBM42,ZBTB2 |
| 1.484e-04 | -8.82 | CNR2 (cannabinoid receptor 2) | protein interactions | 1269 | 107 | 48 | 19454 | 5460 |
PLSCR1,HECTD3,TMX3,TMEM60,HUWE1,ADIPOQ,COMTD1,CCDC47,PREB,SELENOK,YIPF4,NRM,PLS3,RPN1,GDI2,COQ8A,AIFM1,HACD3,EEF1B2,COX4I1,COMT,ADAM21,S100A8,ARL6IP5,TSPO2,ILVBL,PDIA3,TMEM19,DHRS7,XPO1,TMEM203,SQSTM1,HADHA,RER1,PGRMC1,SEC22B,SEC62,PRDX3,SIGMAR1,SLC25A3,FDFT1,SELENOT,SEC61A1,GGT7,B4GAT1,KDSR,TUFM,SLC35E4 |
| 1.491e-04 | -8.81 | ECI1 (enoyl-CoA delta isomerase 1) | protein interactions | 1632 | 56 | 29 | 19454 | 5460 |
ACTB,TAGLN2,DUSP10,ACOX1,FABP5,CHID1,AGR2,HTRA2,MDH1,OAT,ACP6,HMGCS1,CUTA,TF,HSCB,REXO2,UGP2,RPA3,HSPD1,AGA,PRDX6,RAB9A,HSPA8,RPA2,SOD2,E2F4,PPIL3,CDK7,FBXL19 |
| 1.494e-04 | -8.81 | TMUB1 (transmembrane and ubiquitin like domain containing 1) | protein interactions | 83590 | 69 | 34 | 19454 | 5460 |
NECAP1,TMEM14B,TP53,CCDC47,ERLIN2,NRM,DUSP22,TMUB2,FAF2,ADRB2,RNF5,TMUB1,TSPAN5,DUSP9,TSPAN17,SYVN1,RIC3,TRAF6,TUBG1,KCNJ10,CSGALNACT1,RNF139,EDEM1,NFKB1,TMBIM6,UFD1,ATP6AP2,DUSP3,ERLIN1,CAMLG,LMBR1L,STT3A,CD274,SPINT2 |
| 1.494e-04 | -8.81 | MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3) | protein interactions | 57553 | 69 | 34 | 19454 | 5460 |
KRAS,HSCB,STX7,MDC1,RAB8B,BAP1,TMT1A,VAPB,FGFR1,CAPZA2,PICALM,SSR1,TOP3B,E2F4,SEC62,ST7,RAB1B,HNRNPL,RHOJ,FBXO22,CAV1,ESR2,VIRMA,RAB35,CSNK2B,GSK3A,SEC61B,CHCHD4,RHOB,MED4,VMP1,AKT3,RAB11A,RACGAP1 |
| 1.499e-04 | -8.81 | MTARC2 (mitochondrial amidoxime reducing component 2) | protein interactions | 54996 | 41 | 23 | 19454 | 5460 |
SYBU,RAC2,AIFM1,KCNA2,COX14,MGST3,RHOH,SLC25A46,PEX3,HTRA2,RHOG,AKAP1,EXD2,PDE2A,TOMM20,PXMP2,FTL,IMMP2L,SLC31A1,RP2,CDC42,TOMM22,CRELD1 |
| 1.499e-04 | -8.81 | SNX29 (sorting nexin 29) | protein interactions | 92017 | 41 | 23 | 19454 | 5460 |
HNRNPL,CAV1,VIRMA,TRAF1,RAB35,METAP2,AP2M1,GSK3A,RAC2,DCAF5,LAMTOR1,RHOB,LAMP2,KXD1,ATG9A,LAMP3,STX7,TFPT,RAB9A,RAB5A,DISC1,RAB4A,ATG16L1 |
| 1.499e-04 | -8.81 | QPCT (glutaminyl-peptide cyclotransferase) | protein interactions | 25797 | 41 | 23 | 19454 | 5460 |
CFTR,ELP3,DHRS4,DDX39A,HBP1,MFAP1,MED23,NUBP2,NEDD8,COPS5,CUL3,CUL2,STK38L,UBE2H,FGR,MED4,CMBL,HRAS,NAP1L5,UBB,CAND1,DCUN1D1,FZR1 |
| 1.499e-04 | -8.81 | FAIM (Fas apoptotic inhibitory molecule) | protein interactions | 55179 | 41 | 23 | 19454 | 5460 |
GTF3C4,TRIM62,TPT1,QRSL1,DNAJC27,LMNA,SYS1,TRIM11,GNA11,THUMPD1,RIGI,SEPHS1,NAPG,H2BC9,CASP4,SIVA1,RSPH1,GFUS,H1-1,FAS,TNFRSF1B,CDR2L,CSTF3 |
| 1.501e-04 | -8.80 | positive regulation of endocytosis | biological process | GO:0045807 | 157 | 68 | 18204 | 5365 |
MIR183,CD14,IL4,TBC1D5,CBL,MIR20A,CCL21,MIR17,SOD1,AP2A1,SFRP4,CCL19,SFTPD,PICK1,PCSK9,PLA2G5,LYAR,ATAD1,CD151,IL15,CCL2,TSG101,FCGR1A,AP2M1,RAB27A,CAV3,IL15RA,VEGFA,CD36,B2M,RAB31,SGIP1,CALY,VPS28,HFE,APLN,ANGPT1,HSPA8,CLU,SYK,MBL2,PPP3CA,WASL,PYCARD,FLOT1,ITGA2,GREM1,STAP1,HNRNPK,CBLL1,CLIP3,FCGR2B,FCN2,IL2RB,CALR,PPT1,NLGN1,FCER1G,CD63,IFNG,CD47,CDC42,H1-1,TF,IL2RG,GH1,FCGR2A,CLEC7A |
| 1.508e-04 | -8.80 | ribose phosphate biosynthetic process | biological process | GO:0046390 | 202 | 84 | 18204 | 5365 |
DLAT,ACSS2,NME1,PPAT,NDUFB10,ATP5F1A,NDUFAB1,NDUFS8,NDUFA1,UCK2,UPRT,NDUFB7,NDUFA5,ATP5MC3,NDUFA12,COX11,ATP5MK,PDHB,NME2,PPT1,ATP5MG,UCKL1,MMUT,NDUFS2,ADK,GMPS,HACD2,UQCC3,ATP5PB,ACSL4,STOML2,DNAJC30,ELOVL3,ATP5PD,SLC25A1,PRPS1,NUDT2,NPR2,ATP5F1B,NDUFV2,NDUFB6,NDUFC2,GUK1,ATP5PF,NDUFS6,G6PD,PRPSAP1,TECR,SDHC,PDHA1,UMPS,NDUFB8,NDUFA2,PAPSS2,ACAT1,AK5,ATP5PO,ELOVL4,LIPA,SDHB,HACD1,ELOVL7,AK2,DCAKD,UCK1,ELOVL6,ADCY3,ATP6V1A,NDUFB4,NPPC,ADSS2,ELOVL1,CMPK1,ACACA,NDUFS3,ATP5F1E,AK3,DCK,ADCY2,NME4,GUCY1B1,NDUFB5,ATP5F1D,ATP5MC1 |
| 1.509e-04 | -8.80 | ARHGAP32 (Rho GTPase activating protein 32) | protein interactions | 9743 | 141 | 60 | 19454 | 5460 |
EPHA2,PFDN2,NTRK3,PFDN4,RHOB,DCAF4,YWHAZ,SFN,CEP85,SMURF1,VIRMA,ESR2,SRC,ACTB,RHOJ,SEC61B,CRYBB3,GAB1,CTNNA1,DLG4,CDC42,CCL3,ATG16L1,TRIM52,ASB3,GPHN,SQSTM1,HNRNPD,LHX2,YWHAB,RHOG,NCK1,SHC1,YWHAH,SHC3,GRAP,YWHAG,CTNNB1,MDFI,PIK3R1,EGLN3,CAMK2N2,CAV1,FZR1,ARF6,GJA1,RAC2,ETV6,SYNCRIP,RAB35,CRKL,VPS33A,RAF1,PFDN1,FLOT1,PRDX4,KRAS,NTRK2,ZYX,GARRE1 |
| 1.510e-04 | -8.80 | UBXN8 (UBX domain protein 8) | protein interactions | 7993 | 77 | 37 | 19454 | 5460 |
TBC1D17,TMEM14B,PLD3,RPN1,SURF4,STIM1,SSR1,TMEM165,AQP3,SEC62,OTULINL,DNAJC25,ST7,MTCH2,PXMP2,SLC7A1,KRAS,SLC7A14,ADRB2,SLC15A1,SYVN1,DERL1,TMT1A,VCPIP1,ELAVL2,SLC38A1,FAS,UFD1,MOV10,EDEM1,SELENOS,EGLN3,SPCS1,SLC25A4,HSD17B11,SLC1A1,SEC61B |
| 1.510e-04 | -8.80 | Rmdn3 (regulator of microtubule dynamics 3) | protein interactions | 67809 | 77 | 37 | 19454 | 5460 |
NDUFB8,NDUFV2,STOML2,CHCHD3,ERLIN1,PLGRKT,CAV1,MGST3,RMDN3,ATP6V1A,CHCHD6,VDAC2,UQCRC2,CCDC127,NDUFB4,PHB1,FAM8A1,NDUFA12,VAPB,STOM,NDUFS6,OTUD6B,UQCRC1,ERLIN2,TOMM22,RABL3,TXNL4A,NDUFA2,TMUB1,FLOT1,ATP6V1G1,ATAD1,VDAC1,PHB2,CYBRD1,DERL1,ATP2C1 |
| 1.510e-04 | -8.80 | PDZK1IP1 (PDZK1 interacting protein 1) | protein interactions | 10158 | 77 | 37 | 19454 | 5460 |
SFTPC,GRM2,SDCBP,CYB5B,FAM3C,TMEM14B,STX12,TMEM101,PGAP2,PLP2,NSG1,PLPP6,LEPROTL1,ZDHHC17,JAGN1,TMEM203,ERG28,FCER1G,TMEM11,AQP2,C2CD2L,PMP22,PLPP4,SLC35B4,EMC6,TMEM107,CD81,THBD,TRIM54,AIG1,TSPO2,TMEM97,TMEM14A,RPRM,VAMP3,SFXN2,CYBC1 |
| 1.512e-04 | -8.80 | MED16 (mediator complex subunit 16) | protein interactions | 10025 | 96 | 44 | 19454 | 5460 |
CIB2,MED17,CEBPE,ESR2,POLR2B,MED22,MYC,AR,RUNX1,STN1,MED10,SMAD2,MED13L,FBXW7,MED11,ATG16L1,SUPT3H,FBXL19,MED30,MED23,MED31,SUPT7L,SMAD3,MED29,MED21,FOSL2,MED27,MED4,DNAJC7,HNRNPD,EMC2,BAG2,HAPSTR1,H3C1,RIGI,IMMP2L,TP53,MED9,VDR,SMAD1,WBP11,ACVR1,CDK8,POLR2G |
| 1.516e-04 | -8.79 | regulation of transmembrane transporter activity | biological process | GO:0022898 | 222 | 91 | 18204 | 5365 |
MIR200C,VAMP2,FKBP1A,CCL2,KCNS1,TMSB4X,JPH4,SPHK2,ACTN4,SLMAP,PCSK9,CHRM3,PRKCE,CACNB4,KCNIP2,MIR448,SUMO1,FGF13,CRHR1,SRI,CFTR,SCN2B,PLN,NLGN2,ATP1B1,CCR2,ATP1A2,PPIF,CAPN1,DLG1,ACTB,ABCB1,CACNB3,MIR24-1,CHP1,SCN3B,MIR192,CRHBP,TCAF2,VMP1,CLTRN,RANGRF,MIR30D,GSTM2,TESC,MIR208B,CAB39,HECW1,ADRB2,DRD3,COX17,EPO,KCNAB1,CLIC2,CAV1,EDNRA,FKBP1B,NDUFA4,FXYD6,GPR35,PRRT1,CAV3,TLR9,NOS1AP,MIR208A,GSTO1,STIM1,SELENON,MIR212,CACNG3,MIR153-1,CACNB2,WWP2,NLGN1,IFNG,ATP1B3,SCN1B,HPCA,MIR1-1,AHCYL1,MMP9,DAPK1,YWHAH,STAC3,OXSR1,NETO1,HOMER1,PHB2,OPRM1,FGF12,DLG4 |
| 1.526e-04 | -8.79 | SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1) | protein interactions | 25939 | 170 | 70 | 19454 | 5460 |
JUP,CDK1,EIF4B,DUSP14,TIRAP,CFTR,CCNA2,HSCB,B2M,EEF1G,FBXW7,RPA3,HIRA,XRCC5,HSPA8,RNF113A,OAT,UBE2H,CUL3,CUL2,SAMHD1,FBXO7,KANSL3,ZMAT3,RACGAP1,NONO,COPE,ACTB,VIRMA,DUSP10,CCNF,LMBR1L,CMTR1,GANAB,GSK3A,PPP2R5E,POLR3H,EZH2,CHMP4C,SERPINA1,RAF1,KBTBD4,FAM13B,SUPT5H,TXNRD1,EEF1A1,PPP2R1A,AKAP12,KPNA2,TF,FBXO25,MSH6,FAF1,TRIM21,TUBG1,RPL24,RSBN1L,FAM174A,CD81,MAP3K14,SUMO2,OSBP,PPIA,EGLN3,OS9,AIP,PHB1,FBXO32,DSTN,SEC23A |
| 1.526e-04 | -8.79 | AK4 (adenylate kinase 4) | protein interactions | 205 | 170 | 70 | 19454 | 5460 |
MTRF1,GRSF1,LAMTOR2,MMUT,CCL5,AK2,TMEM70,MRPS26,NQO1,SSBP1,GATD3,RPL35A,CAV1,CEP19,RAF1,LYPLA1,CENPM,GLRX5,METTL15,GTF2E2,NUDT19,PDHA1,ACADSB,FAM136A,MSRB3,PREPL,NSDHL,HSPD1,TCOF1,BCKDK,UNC50,HINT2,PC,COX8A,GUK1,FGF12,FASTKD5,MTG2,AUH,CABCOCO1,PMPCA,MTPN,AK3,CFL2,ISCA2,PCCB,TUFM,UBE2H,FXN,NIPA2,TACO1,CCDC90B,ENO1,TXN,TXNDC12,CPT2,SH3BGRL,RABIF,COQ8B,SNRNP27,GABARAPL2,ZMYM6,MTRES1,PEBP1,EXD2,COX17,GFM1,NPTN,HSCB,GRPEL1 |
| 1.526e-04 | -8.79 | PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) | protein interactions | 5286 | 170 | 70 | 19454 | 5460 |
RHOBTB1,GTPBP1,NUPR1,FAM136A,CAPN2,CAPZA2,LGR4,ACTN4,TMSB10,RAF1,RIGI,PTGES3,DUSP21,TRIM37,BAG2,HNRNPA2B1,YWHAB,NQO1,STAMBPL1,DNAJC7,FKBP4,EIF5A2,ATG7,YWHAG,COPS5,YWHAH,ATG9A,NUP35,EGLN3,STX6,RAC2,SEC23A,MAGED2,MAP1LC3A,EEF1AKMT3,STAMBP,RPLP0,PICALM,RPA2,CDC42,PPP1CB,RND2,ATG16L1,TOMM20,CRYL1,STAU1,AKAP1,THBS3,PGK1,HSPA8,RHOU,RPA3,STK24,YWHAZ,FBXW11,MYO6,LAMTOR1,SFN,CSK,MYC,CDC16,VIRMA,ESR2,AKR1C2,ANAPC2,RMDN3,POLR3B,TRIM27,TMEM74,SMAP2 |
| 1.526e-04 | -8.79 | positive regulation of production of molecular mediator of immune response | biological process | GO:0002702 | 135 | 60 | 18204 | 5365 |
MAVS,SPHK2,HMCES,RIGI,TICAM1,TLR7,TNFRSF14,IL5,MAD2L2,EXOSC3,B2M,SEMA7A,CD36,CD28,LACC1,KIT,IL4,TRAF6,MYD88,NLRP3,XBP1,TLR9,TNFSF13,CD81,DNAJB9,IL2,VAMP3,DDX1,IL10,XCL1,TLR3,IL17F,TRIM6,PHB1,IL13,TFRC,CD86,KLK5,IL21,TRAF2,SHLD1,RSAD2,CLEC7A,IL6,KMT5B,CD40,IL1B,LILRB1,HTR2A,BCL10,MIF,IL18,SASH3,SYK,MZB1,TLR4,PYCARD,STAT6,KLK3,PHB2 |
| 1.546e-04 | -8.77 | UBFD1 (ubiquitin family domain containing 1) | protein interactions | 56061 | 51 | 27 | 19454 | 5460 |
CKB,LDHB,YWHAH,YWHAG,ZNF622,FERMT2,TMEM248,APEX1,G6PD,NFKBIA,UBE2S,PBDC1,RPA2,PAK2,KRIT1,NHERF1,ISOC1,CNDP2,GNAI3,PSMC3,PSMC4,SEM1,CSE1L,HNRNPK,EIF4E,RPA3,EWSR1 |
| 1.547e-04 | -8.77 | respiratory chain complex | cellular component | GO:0098803 | 80 | 39 | 19108 | 5553 |
UQCRC1,NDUFAB1,NDUFS3,SDHB,COX7A1,COX6B1,NDUFA2,NDUFS2,NDUFA4,NDUFS6,UQCRH,COX7B2,SDHC,COX5A,NDUFB7,NDUFS8,NDUFC2,COX6C,NDUFA1,UQCR11,UQCC3,NDUFB10,COX4I2,COX6B2,NDUFB4,NDUFV2,UQCRQ,CYC1,COX7B,COX4I1,NDUFA5,COX6A2,NDUFB6,UQCRC2,NDUFB8,BCS1L,COX8A,NDUFA12,NDUFB5 |
| 1.548e-04 | -8.77 | intracellular anatomical structure | cellular component | GO:0005622 | 15205 | 4510 | 19108 | 5553 |
PLAAT3,TOB2,PLEKHF2,WBP11,RPP21,KIT,TMEM266,PPP1R3C,ACOT6,C2CD2L,PRSS23,CTNNBIP1,TMEM147,PLSCR1,RNASEH1,SERPINC1,CDKN2C,HSPB6,METAP1,CEP57L1,MCPH1,LASP1,CSF2,TNNI3K,PPAT,KLHL12,SENP5,HMX2,IDH2,ATP8A1,MS4A7,KCNJ11,CPNE1,PCSK9,GTPBP8,EGLN2,PARP11,POLR3GL,NUCKS1,SNX11,KHDC4,SMYD3,AGAP2,CIAO1,PAK5,EXOSC1,MRPS9,YAE1,ZDHHC15,RBM17,CD2AP,GJA1,POLA2,NRSN1,AR,SELENOO,H2AX,FGF3,EWSR1,ADIPOQ,IRF4,MCM4,TMX4,LDAH,RBFOX2,SCFD1,HEY2,ZBTB5,VRK1,ACAP2,REXO2,MAGEH1,RNF144B,CLLU1,SLC25A46,WRAP53,ACTN4,HNRNPA2B1,CLU,PNRC1,DNTT,NUDT3,SYP,RASGRP2,BIRC5,AGA,MT1M,DIS3L,JUP,MRPL17,AHCYL1,SF3B5,ORMDL3,POLR2C,NSDHL,PKP4,FOLR1,ELAVL4,STK3,DSN1,GIMAP4,MNS1,RPS3,NEK9,ADRB2,NMRK1,MPC1,THBS3,OLFM2,NLGN1,DCTN4,TCEANC2,FCGR2A,SRXN1,HAND2,COX11,AP1G2,CMC4,SUPT4H1,ABCC5,PSMB3,CFL1,RPIA,TRMT6,SMPD2,CYP26A1,SMNDC1,MARCHF4,ERCC3,ADRA1A,ACTR1B,MPG,DOK6,ZBTB6,CPLX1,ZMAT2,TTC8,NDUFA12,HSPE1,CCDC86,NFE2,SLC35B4,DDAH1,NMI,RSRC1,EDEM2,HS3ST1,COX7A1,IVNS1ABP,ACOX1,RGS1,TPD52,PTPN1,PCGF3,MRPL13,FKBP8,BMERB1,FOXP2,CPLX2,MAP3K12,MAP4,PGS1,TRAF2,HINFP,ATP5PB,PLS3,HCRT,NSFL1C,NME4,TCEAL8,SNAPC5,PABPC1L,ARL6IP6,MFAP3L,POLDIP2,DISC1,PPP1R1A,USP3,SH3GLB1,CITED1,SEC22B,IL2RG,SAP18,USP13,PLAAT5,OTULIN,ECD,MRPS21,SERPINA1,URM1,ABHD4,HELT,RAP1A,THNSL1,BCAP29,SYNGR2,DNLZ,PIP4K2C,SELENOK,EIF4B,RNF20,MTRNR2L3,UBN1,VTI1B,ACTL6A,SKA3,ACER3,RNF181,ESS2,AKAP14,IDH3A,CBFB,HSD17B8,NUDT5,ITM2B,VDAC2,MRPL22,SMDT1,SDHB,ENC1,DTWD1,HSP90B1,STK4,UMPS,RPL10A,DELE1,ZNF174,CRMP1,IFRD2,FAU,RFXAP,ATP5F1B,TRIM15,IFT52,SLC25A4,MMP14,PPP3CA,KCTD10,SNRNP40,GRIA2,CLSTN3,TRAPPC6A,HGS,FASTKD5,NFE2L1,ANAPC16,CD46,MALSU1,CCNQ,PNO1,ETF1,VCPKMT,ERP29,FGD2,EIF2B2,DPH6,SASH3,NOB1,IGF1R,RAB33B,OS9,IZUMO4,CDK20,HS2ST1,PGAP3,MT1E,ZNF740,TOP2B,SSR1,RPF2,BCKDK,NUP42,COQ8A,EAF2,RNF5,NRDE2,RETN,RGS5,LACRT,KCNIP2,CST3,SLC35G2,AKT2,ZNF805,RHOH,DSTYK,NTF4,SEC13,TMEM209,KCNH1,RPS10,LMBR1L,RAB27A,GPAA1,CA2,NDUFA4,SELENOW,GMNN,TRAF3IP3,TMEM11,CERS2,PDIA2,KDM4B,ARGLU1,SPMIP9,SLC39A13,SEC23A,ATP6V1G1,WDR12,JAK2,DIO1,CD1A,PPP5C,ZC4H2,PLD3,DDX23,SRC,TFG,MMD,STX12,CNIH1,COMMD6,SORD,TM4SF20,ARMCX2,CMTR2,MMP28,THAP6,SRSF1,SULT1A3,TRAPPC3L,RND3,DHRS4,XPO1,LYPLA1,AAMDC,PHACTR1,DES,AVL9,SLC35A5,RBBP8,NKAP,CTNNA2,IGFBP3,ARFGEF1,GPX1,BRAP,CRADD,VIRMA,RAB5C,CARS1,GHITM,SYN3,POLL,RAB35,CHCHD3,SLC25A28,PRKCB,RHOBTB3,PPFIBP1,PEDS1,ZFP1,GGH,CMA1,SLC35D1,COX6B1,WDR77,RPL27A,FTHL17,TCEAL1,RPS12,CD1E,MIR9-1,B3GALT4,MSMB,TRMT5,FBXL3,ID1,CREBBP,GNB1L,ARL4A,YES1,TRIM37,SSBP3,CENPL,TRIM5,CASK,CEP70,PLAC8,RPAP2,PHYKPL,CSTF2T,PSMB7,SLC35F6,ETNK2,CAPN1,COQ8B,AQP11,SMAD5,VPS28,VCPIP1,TMOD2,MOV10,KIF1C,DDIT4L,MKKS,DMTF1,NTMT1,DFFA,FAM118B,SDS,CLIP3,SFRP4,SATB1,MT1X,VWF,EEF1G,LAMB2,NFKBIA,ABCB9,SFTPC,MTRES1,AGPAT5,CLK1,HNRNPF,BOLA2B,STX11,MRPL50,BTF3,SCN3B,UCKL1,ZNF322,METTL21A,GNAI3,TBC1D1,RNF10,SIN3A,CXCR4,FABP7,LMNA,WDR19,RNASEK,ATG101,FAM169A,GFPT1,SNRNP70,UBE2V1,CLDN9,CCHCR1,G6PD,KCNIP3,ERLIN2,CLPB,CYB561,ITGAV,CMPK1,TMEM59,NCOA5,PSMC5,GPR15,SLC2A1,TERT,CDC73,SPATA2L,COPE,ATP6V1E2,VPS72,PREPL,RIC3,FAM156A,PARD6A,ITM2A,SCML2,NDN,CHST1,RNF182,ATP6V1A,XAF1,ZNF397,PDAP1,H1-10,PLG,LIG3,FOXJ3,NSMCE3,PRKCA,OSTM1,ALOX5AP,SIGMAR1,SNAP25,ASB1,SS18,SETD7,WDR11,COX7B2,ABHD5,FKBP1B,GPR137,RPL31,ZCCHC9,DAG1,HSD17B1,MATR3,GLYATL3,SLC25A23,SLC25A24,H2AZ2,CXCR3,CTDSP1,H1-6,TYMS,CMAS,DCUN1D3,SOX2,LZTFL1,ZNF593,DLG1,LCA5L,WASF3,CENPW,MORF4L1,NAPG,PYGB,RAB39B,CSTA,PIH1D1,INPP5K,ANKRA2,CDH11,ACO1,MTDH,ELK3,FKBPL,SAMHD1,SYNE4,BPNT2,RPL18,SHLD1,ATP2C1,MAGED2,CRABP2,LIN7C,ZNF688,DNASE1L1,BCL7C,FMO3,FKRP,RRAGA,SLC35C1,IL1B,CAMK1,RPL24,FGF22,CDC42EP2,SLC11A2,ZNF592,BCL2L1,CHRDL1,SCG2,EEF1AKMT3,DCK,BMPR2,BCL9,POGK,MRPS16,CLTRN,TFCP2,SLC25A21,ZNF526,TAF9,GSK3A,PHF21A,PPM1G,NDE1,ATL1,SQSTM1,MPP1,PDE2A,ATP6V0B,ZBTB14,NFYB,TMOD3,ST3GAL1,CCNI,GTPBP1,MYG1,NCALD,FEM1A,CENPP,APEH,TUFM,SEC63,TCF23,MIR29C,CALML5,CCM2,TRIM63,MFAP1,RPL8,DRD1,PCYOX1L,ZBTB2,RASL10A,FITM2,ZNF668,ATP1B3,MACO1,PRRT1,MRLN,PDE1B,IZUMO1,RBCK1,CRYAB,TNKS,INPPL1,ACP2,AGAP1,NCKIPSD,RAD21,RBM27,ATF3,SSU72,LORICRIN,TENT4A,RNF122,SLC6A3,FCER1G,CETN2,TMEM38B,POP7,DDX1,LARP4B,EIF4E3,MID1IP1,EID1,SNAP91,YWHAG,RPP14,MFN1,PARM1,TOR2A,STUB1,OPRK1,TST,DHX15,RAMAC,REP15,RPS27L,PXYLP1,DRAP1,RP9,PIAS1,TRAPPC6B,NDUFS8,FOXS1,TCIM,SLC35B3,MAK16,DCAF11,GRPEL1,PHAX,THY1,SLC35A2,SOBP,TMCC1,MIEF1,DUSP6,SFXN1,HYCC2,RB1,ATG4A,INO80E,BCL6,SLX1A,FBXL7,TCEAL7,SLC25A20,CDK7,TRIM11,SAP30L,VMP1,RAMP3,PCNA,HNRNPA1,PRDX2,UQCRC1,ZDHHC4,MOBP,DUSP1,THOC2,TERB2,SNRPG,UBE2G2,RNF148,CHKB,RSL24D1,POC1B,DYRK2,HSPD1,CYP11B2,SEC22A,CD58,NKX3-1,ALKBH2,OGG1,PFDN1,IPCEF1,CYP4F22,HIKESHI,ATP5MK,CSK,TTC4,MRPS18A,CERK,DVL2,ZDHHC24,TPH2,IP6K1,PRELP,ANKRD10,EDEM3,GLCE,DBNDD1,SP4,MSL2,HSBP1,PTDSS1,IMP3,CDK12,DEDD,BRINP1,LUM,TRIM21,NR1I2,TMEM167B,STAMBPL1,PHF7,CFAP90,GPBAR1,ADH1B,SCLT1,SHC3,TDRD7,DNAJC3,SERPINA3,KRTAP8-1,MIR29A,ACVR1B,LPAR2,GSTO2,COPS4,GK2,ITGA2,USP8,AKAP1,TBCE,BTG2,KPNA2,ISYNA1,IER2,NUP35,CD36,PTHLH,GSTM3,LHB,LSM3,TSPYL4,CCDC42,GMPPB,PSME1,ELP6,MRFAP1,STAMBP,SUPT3H,HERC3,ZHX3,LLPH,LGI1,CHCHD1,SDC2,EXOC2,SHPRH,MOB3C,RBM23,MEF2B,GLRB,GPD2,CDKN1B,G2E3,AGGF1,GALNT12,SEMA4C,CIRBP,TCEAL9,TXNDC17,FAM162A,CRYGD,GTPBP2,HINT1,RALGAPA2,PRELID1,SYNCRIP,SMG5,UBLCP1,ECHDC1,SHMT1,ZDHHC16,DCAF4,BAZ1B,NDUFV2,SLMAP,TRIM44,CDC42SE1,UPK1A,LAMP5,TRAPPC3,RND2,RRN3,SNX14,AKR1C2,PICALM,NETO1,MGAT4A,ATP1A2,CCSER2,MYLIP,ACAA2,SF3B6,MECR,FERRY3,ATAT1,SNX20,CCT5,NPR2,NPC1L1,GINS4,FAXDC2,SRSF12,TMED4,OGN,KLK6,CXCL1,LMO4,PPIL3,SNRPD1,GABPB1,CPNE2,CYP4V2,ARCN1,RNF11,MRPL18,CYP1A1,BRD3,YTHDF1,ROCK2,ELOVL1,BATF,FAM98A,PTGES,GNA11,KCTD15,FABP4,NUP37,DDX50,ALKBH3,PREP,UTP6,TDP1,TSG101,PPP2R5E,PGAP2,ASB7,GAL3ST4,KLF12,FLOT1,OAT,CDK4,POLDIP3,PLEKHJ1,COG1,DDX42,NEO1,FCHSD2,DOLK,NHP2,ZMPSTE24,MOSMO,COPZ2,PIM2,ZNHIT1,LYRM2,DUSP22,COX6A2,FEZ1,FEM1B,HSPA8,KLF1,PELI1,TNNI1,USP2,GRPEL2,DNAJC27,PAQR8,SPHK2,CSNK2B,ZSCAN1,NPM3,POLD2,GPR37,TOX4,CD38,SPPL3,DUSP18,SMARCD3,SSBP2,OPTN,ATP6AP2,RPL26L1,TPST1,RIMS4,TMEM74,SPG21,ETFRF1,MTHFS,CPT2,ACADS,SELENOT,CMBL,TSPAN15,RMND5B,SMARCB1,RFC3,APPBP2,OPA3,CUL3,CFTR,GRB10,GLTP,CYB5A,EDEM1,GALE,FAS,GTF2H4,RPLP0,FAM3C,CYP7A1,WWP2,KLHL22,RRAS2,EMX1,CDIPT,ITK,BHLHA9,ALPL,CSNK1A1,SLC32A1,NRP1,GLYAT,PSMA1,MAX,SPP1,ATP5F1D,APOO,SYNRG,LYAR,MRPS34,NOTCH2,ING5,SMAD3,MSANTD4,HINT2,EXD2,SACM1L,CTU1,GNAZ,MTF1,HINT3,ASZ1,TAPBPL,PCGF2,UCP2,RSPH1,CHCHD2,RTN4,PIK3R1,RTRAF,LIPT2,SHOC1,TADA1,GTF2F2,PCSK2,SESN3,RAB4A,CCL5,TENT2,ARB2A,UBP1,PYCR2,SEC62,SMN1,VLDLR,C9orf72,LARGE1,TSN,SURF2,UBE2F,NDUFAF2,SPIN3,LPXN,TRIQK,ZGLP1,OAZ2,TXNDC12,KDM2A,PRKCE,TMEM95,PIP4P2,PCBP4,NOL4,GGTA1,TIMP1,SLC17A5,FAM110B,TAFAZZIN,DGCR8,ZNF574,CLVS2,KLHL25,COIL,RNF41,CALU,PEA15,PAX6,SNRK,SNX33,MAGEB1,NDUFB6,GMDS,POLR2L,AZGP1,LMAN1,NOPCHAP1,ATRAID,CIMAP1B,CYP2C18,AHSA1,SH3GLB2,HTR2A,UFL1,RAB23,PKIG,PPP1R1B,DDX46,MIR638,UAP1,ZMAT3,MLH3,IL23A,ARRDC3,RAB22A,TSEN54,SVBP,EED,GABRB2,ACTL6B,UBE2A,VEZT,CDC42,MAPKAPK5,GRAMD2B,MAP1S,MIEN1,TMEM199,TXNRD2,TRAPPC10,HMGN4,ZBTB17,ZNHIT3,ZRANB2,PSMA6,UBL5,PGPEP1,OXCT1,SERPINI1,CSNK2A1,CAV1,SCD5,ANAPC13,UQCR11,MAGED4B,GTF2I,DNAJC1,CDC16,ACAT1,SART3,NUBP2,ADCY3,KCNQ5,EPHX1,EIF1AX,NOP58,H2BW1,GPX7,BET1,TIAM1,CPLX3,PNMA1,PRKACB,NREP,UCHL3,TOMM6,CFAP68,RNF146,CIPC,APOBEC3F,GSTK1,FHOD3,SCHIP1,CHN2,GCLC,UNC45A,MAGEB10,KIF3C,ABHD12,MLLT6,RAB2A,NHEJ1,STK11,SLC25A45,BLOC1S5,FGF16,TSSK1B,RHOG,OAZ3,SNAI3,MED9,SNX3,NOP16,HUWE1,APOBEC3C,POU5F1,TMEM88,ZNF511,SMAD4,THUMPD1,RAB30,PDRG1,MBLAC2,UBIAD1,ZNF24,ACTB,ASF1A,PYROXD2,DAPK1,PPP1R8,PPTC7,SLPI,SERTAD1,ARF6,CABCOCO1,GABRA1,GAB1,DNM2,FRS3,TXNIP,CLCN6,GTF2E1,CYP2C9,ELOVL6,TOR4A,RGS19,CLDN11,LCP2,SLC35F1,DAAM1,MRPS23,MORC2,PHF12,GZMK,CDK6,TMEM30A,HTRA1,PIR,SLC16A10,ZNF596,PRPF18,PLCB2,ADPRM,GDI2,MYD88,FERD3L,ETFBKMT,LDHAL6B,SKP1,NMBR,DHRS1,CGAS,PLA2G4B,MAEA,KPNA1,UQCC2,PSMA4,COX16,F10,CRTC2,CRYL1,SERINC3,FZD3,PFDN2,MRPL51,FSTL1,RGS10,ETV6,STAT1,RACGAP1,GK5,SEMG2,MSMP,NDST1,THAP7,G3BP2,LSM14A,TRIM34,CISH,UBE2K,DHRS3,MEPCE,SPINDOC,SLC22A17,PRL,GDPGP1,CCSAP,HACD2,SLC51A,YKT6,LYZL6,CDC20,WDR82,DPH5,CCNA2,PRIM2,SRP72,UQCC3,POLR1B,TULP3,BORCS6,TIMM13,SLC35E1,GNA14,PFDN6,HSPB1,PITHD1,SYNDIG1,MTPN,HP,RPGRIP1L,GCFC2,NR0B1,RPL23,SRPRB,VAPB,PACRG,MED22,SLC25A10,HR,GSKIP,SRD5A3,TAS2R16,RGCC,RTCB,CCNF,RBP5,HSCB,RARRES2,AREL1,MTERF2,SLC6A4,TFE3,GSTA4,HSP90AB1,FURIN,GTF2H5,CAND1,TREML1,MTMR6,ERO1A,AIF1,GSTT1,IFIH1,DCAF16,LBH,ATP6V1G2,SDCBP,TTLL10,PGK1,EZH2,FOXP4,OARD1,NOA1,BCAS4,BLVRA,MYRF,CARTPT,PRDX4,RAB40AL,TES,SOX21,B3GNT2,JKAMP,CYP2C8,CLXN,RPRD1A,EVA1A,RAB3B,DLST,PRCC,CD274,DYRK1A,TMEM14B,TLR2,TRIM35,WDR44,RBM5,ZFAND6,PSMD14,CCR1,FAHD1,SELL,RDH11,RPAIN,SCML1,CLN8,ABCF1,MRPL11,ALKBH4,GFM1,ICA1,F9,TRAM2,UQCRH,SLAIN2,CLRN1,BOK,UBE2D1,GFUS,CCDC181,MED10,FAXC,IFRD1,LILRB1,PPARG,DOHH,BHLHE40,CHP1,H1-5,TIMM29,RNF113A,RC3H2,FTL,AGTRAP,SLU7,CD2BP2,SLC35E4,SLC25A32,CIART,OPRM1,ADH1A,NSG1,DDIT3,NDST3,UBXN6,CD2,SERTAD2,TSEN34,ZNF790,GCHFR,STARD5,FUNDC2,GAS2,GPC1,DNAJC2,NDUFS6,ATXN1L,RBM7,RAB14,SLC38A2,DSTN,NR2F6,CAPN2,LAMTOR3,MRPL53,CYP2D6,ALG11,TANK,NEUROD2,RERE,ZBTB45,GTF2A1,PAX9,HNMT,BET1L,CSNK1A1L,ZNF436,PSMG2,HDAC11,FYTTD1,CYB5R4,DCTN3,EFNB1,RMI1,MEF2A,SARM1,FABP12,TUBG1,HCFC2,FBXO44,CCDC65,SGIP1,DNAJC7,OPHN1,GOSR2,TP53INP2,MYL12A,SFTPA1,HRAS,FUNDC1,TPPP3,HOXB1,CDAN1,PRDM4,EMG1,TIMM23,CSH1,HAUS2,TAX1BP1,NUP153,MGME1,MAT2A,NDUFS2,GLRX5,GALC,RBM22,ANKIB1,PEG10,ZNF652,PSKH1,NUS1,LAMTOR1,TIMP3,IL12A,RPS17,TTL,NUDT9,SYCE3,RPS5,KLK3,SLC25A44,PDHB,TRIM46,GPC4,AGK,IFT25,MAF1,ACACA,NAB2,CDK9,FUT1,UHMK1,LGI3,TEX19,ARF1,ADK,GNB1,WDR37,APH1A,CCR5,ACSL4,SCAMP5,THG1L,NQO1,PDSS2,MT1A,BUD23,STAP1,URAD,CNOT2,TMEM123,PGRMC1,HNRNPL,RPS6KA4,SFT2D2,TVP23B,DYNC1I2,SERPINB10,HTRA2,STX1A,YPEL5,CAP2,PTAR1,FBXO31,RAB9A,MCOLN1,CHST2,VGLL2,CHMP2A,POMT2,SUMO1,AVPR1B,CRISP1,POR,OCRL,WNT7A,TBC1D5,SPRR1B,COP1,PPIC,RTKN,PRPF31,TRIB1,CISD1,CDC42SE2,RABAC1,DNTTIP1,MYCT1,DBT,LYZ,CD1D,CBL,KXD1,LYZL4,C1D,APOBEC3A,SETD3,METTL6,PMM2,CYTH1,PRDX1,UGP2,SF3B4,H2AC6,STARD4,CAPG,BANF1,TRA2B,BCCIP,INPP5E,CNOT6,CCR7,LDB1,DNAL4,SLC4A8,RCHY1,CREB3,PDE7A,SELENOF,PTRH2,SPRED2,GTDC1,TRIM3,BFAR,KMT5B,CNOT7,MAP3K21,CYBC1,MYL12B,UGT1A1,EI24,AMACR,JPH4,CX3CR1,WDR83,SAMM50,EHBP1,CEP85,UBE2E2,HFE,SNRPE,FBXO22,GABBR1,FXN,ARG2,TFB1M,TWIST2,MRPS26,DPEP3,ATP5PF,FLCN,RPP25L,NEU1,PLCL1,CST11,SYVN1,PROX1,VSTM2L,KGD4,MREG,EIF5A2,CCR2,RUVBL2,SIAH2,RLIM,LTBR,ACHE,ZBTB16,CHMP1B,SPTAN1,ISG15,B2M,NKIRAS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APK4,FTSJ1,ARL2BP,SERPINH1,PPAN,CALR,CSE1L,ATF4,SDHAF4,MKLN1,BABAM1,CD1B,PRICKLE2,ELF1,MRPS35,NR1H2,DYNLRB2,SLC30A5,IL6,PIP4P1,PRR19,FAM136A,EMC9,CAMP,OGDHL,DIO3,CAMSAP2,TSR2,SPRED1,NOP53,UBE2M,RASL11A,SLC25A27,SLC25A42,CD247,FGF7,APEX1,CDKN3,PSMD3,BUD31,MRPL20,NLRP6,CYB5R1,RIT2,S100A8,TAB1,METTL18,PGM2L1,SNRPB2,MMAA,SPATA2,SELENOI,DIPK2A,PPIA,PRPSAP1,MGAT1,CAPZA1,MLLT11,NLRP1,SDHAF2,CEP41,SCP2D1,KCNJ8,TOM1L2,FAM20B,MCAT,CNIH4,SNX18,POMP,AP1M1,ST13,TYROBP,CBLN3,IRF6,FKBP10,BICD2,AZIN2,DECR2,OXSR1,AASDHPPT,FTH1,SP1,RANGRF,TNFAIP8L2,MAFG,BACH1,RIOX2,RPL7,PITPNB,SRP54,TNF,CFAP95,MRPL23,GNL1,RGS2,PAXX,SST,RBM15B,HBB,OAS1,PEX3,TMEM203,HNRNPH3,SLC25A31,BCS1L,WWP1,CHDH,GAL3ST1,TGFB2,IRF2BPL,CCDC172,YWHAB,GALNT17,CYB5B,TAF11,ERH,RAG1,TRAPPC4,VDAC1,TMEM50B,PIGY,HMBS,CYP27B1,B9D1,DCTD,KCNB1,DENND6B,GKAP1,ST6GAL1,ZDHHC17,KCNAB1,FAM50B,RNASEL,EEIG1,SCG5,KLHL24,RUNX1,INSM2,IDH3B,FGF23,DNAJB2,PSMB10,ATP1A3,RNASET2,TRMT11,NGDN,TMEM208,ATP6V0E1,LSM12,SLC2A3,CDR2,ST6GALNAC3,TXN,TMEM127,SNCG,ZBED3,CD34,LITAF,OIP5,SERPINB1,GALNT4,POLR2G,PTGES3,HACD3,TMED1,ZNF581,HPGDS,TUBB4B,NCK1,TNFAIP1,BBS5,ATP5PO,TRIM26,ABCG2,MOB3B,MAPKAPK3,ING1,DAD1,PPP1R18,SPATA4,TLR6,RAF1,S1PR4,MRPL52,ROMO1,CD248,JMJD8,TSR3,INTS6L,SNRPB,COX4I2,LPAR1,CDC40,TMED5,CORO1C,PPIF,PPIB,SPOPL,FGF12,VPS4B,NACC2,GJB2,HSD11B1,FBXO25,TF,MX2,NME2,PLPP6,WDR20,TFEB,CLDN14,BAK1,ZNF207,ARHGEF6,RPL22,ATP5MC3,IRF9,AQP3,SSR2,PPP1R16A,DNAJC8,MTARC2,SLC25A5,EIF4A2,BRI3,RAB31,TAF1D,ARL6IP5,NRBF2,RDH12,H2AC1,OSBP,RPL13A,TCF19,HPS6,PDE12,SYNGR1,FGF10,GOSR1,P4HA2,KLK9,FOXI3,PID1,TAX1BP3,PHYH,COMMD5,ZBED1,MACROH2A1,SPCS2,MYC,ST8SIA5,CHST11,ACP5,SOX3,PRMT6,NOP9,PTTG1,GGCX,ZHX1,STXBP1,PTPMT1,PMAIP1,ZMYND19,SELENOM,DCLRE1C,CCDC3,SIX5,MAT2B,ATG4C,MMP9,KIF3B,EXT1,MED31,DESI2,SEPTIN6,SMC4,NKRF,CCDC47,ALDH1L1,DCUN1D1,POP5,SCAMP2,RAB13,UPF3B,LHFPL2,FMO2,CREBL2,USE1,UCK1,PYCR1,MIR214,LMO2,GSTO1,RPL29,MIR181D,MIRLET7I,CBX7,USP38,GHRL,VAMP1,NABP1,MIR223,TMEM108,LACC1,RPE,ELF5,EID2B,IMPA2,PI3,RPAP3,MYEF2,WASL,FGR,PIWIL1,FPGT,MSRB3,AKR1E2,SIAE,KBTBD13,MDM2,NUDT7,MARCHF9,ZNF671,NFKBIB,AURKAIP1,EIF4EBP3,ARHGAP19,UBE2W,NIPA2,CYP3A43,MLC1,FKBP2,KRTAP4-1,HACD1,PSMB2,DEK,SMU1,DHRS7B,GOLGA7B,H2BC9,PDLIM4,EIF2D,IFI27,HSPA5,DNAJC5,ALKBH5,JPT1,PTGFR,CPTP,PIWIL3,RBPJ,JAKMIP1,CEP97,CYP2F1,FUBP3,TLE1,COX6C,GARRE1,ARL14EP,ARMCX1,FOSL2,E4F1,SRSF10,KLHL9,XRCC5,RHOU,SHISA2,TRAF1,GALNT2,RER1,LTO1,MAGEA4,FN3KRP,KRT222,H2AZ1,AIP,HSD17B3,RIMS3,BLOC1S2,PAGR1,EMC10,TADA3,FATE1,EFHD1,IFI6,CNN3,TMPO,PLA2G15,RGP1,KPNA6,CCDC134,RPS7,FBXL4,SHC1,IL2RB,PPM1K,SMURF1,MRPS33,MTRNR2L7,SMAP2,MRTO4,SPTBN1,PPIL4,TSC22D3,NDUFA5,UBL4A,RPL35A,HPCA,AP1S2,RPF1,ANKRD34B,LDLR,DNAAF10,TTI2,TRAF3IP2,GGPS1,RABIF,SYPL1,TUBA1A,TESC,ADO,RBM41,XPNPEP1,PCBD1,JRKL,TEX26,PRKD3,SNCB,GFI1,DLAT,TNFAIP8L1,FDFT1,SULT1B1,RBMS2,ROGDI,CMTR1,PSMC1,RBBP9,RPP25,CHPF,H2AJ,ZNRF1,KIAA0513,CARHSP1,ISG20L2,EEF1B2,NRSN2,DDX39B,FBXW7,RGS7BP,PHB1,ST3GAL2,MMUT,SDHC,CAMK2G,BORCS7,TEX264,RHOBTB1,ZNF280B,PPP4C,PDLIM3,DNAJC24,GLOD4,MIR21,RPL28,ZBTB33,CNOT8,CASC3,MACIR,MSN,ZNF7,ARL4D,CD9,ESYT1,FUT9,CPEB1,ADD1,CNDP2,HARBI1,IL1A,RPRD1B,PAPOLB,FEM1C,H1-1,NOL12,RNF103,GRIA1,CCDC90B,MRPS17,ZNF189,MRPS7,MT3,CYP3A5,GATAD1,BEND5,CCDC174,HNRNPDL,SERPINB11,CDC123,SUB1,AAMP,GTF2IRD1,UBE2S,TOMM70,RMI2,NAA11,VEGFA,FOXD3,COTL1,ARL6,ANXA7,TFPT,EEF2,IFI16,SFXN2,COX14,DCAKD,SLC25A12,CD40LG,PPM1B,EXTL2,PKNOX1,HILPDA,ZBTB39,MAP1B,FRA10AC1,ATP1A1,ZNF513,PEX26,RBM18,INTS10,NXT2,GANAB,CNPY3,AKR1A1,LECT2,PEX13,GYS1,PADI2,ALDH1A3,CHMP2B,STX8,CX3CL1,AP1AR,GPR89A,HBP1,PLAGL1,HBE1,MGMT,TESK2,FKBP14,PET117,RGMA,PDCD5,TUBA1B,LAPTM4A,GNPNAT1,FCF1,RALA,PSMC4,SERPINA5,ABITRAM,AGPAT1,CA8,CSTB,UBE2N,SGMS2,TMEM87A,SNTA1,ZNF326,EP300,SF3B1,CTSB,KCTD17,RIMKLA,MARCKSL1,PDIA6,GSTT2B,RBM38,RNF7,PTP4A2,TOX,CCND1,FNTB,TPPP,POLR2I,MRPL12,CCDC22,HSPA13,CYP27A1,FBXL14,MRPL49,TNFAIP3,XPOT,ZNF175,MITF,FAM13B,ACTA2,GNPDA1,RASD1,COX10,KRAS,DNAJB6,HMG20A,CFL2,DUSP19,HEBP1,SUPT5H,FARSA,TMT1B,CWF19L1,SYK,SFTPD,BCL7B,ENY2,AP2S1,FXR2,ZNF365,POLR2D,FKTN,KLF9,HCLS1,RAN,CBX5,TAMM41,PIK3R3,ZNF250,USP5,ELK4,FAM161A,ATP6V1D,SWAP70,LMNB1,TIFA,MCM3,LYNX1,HSPB8,SNRPA,CNRIP1,UBE2V2,HNRNPA0,NAPA,TESK1,TXNL4A,PHKB,ETFA,ZC3H15,PCK2,BAX,TACO1,STX16,CFAP161,HIGD2A,NTAQ1,CHID1,BEX3,MAP2K3,MED17,BAP1,PIWIL2,SLC39A7,TMEM14A,PRPF19,ACP6,HMOX2,TNPO2,CXCL14,SPMIP10,PHKG1,RNF128,SEPTIN7,FNDC8,LDLRAD4,H2BC11,MEIOB,OLR1,SENP8,ELOC,NECAP2,PGA4,FKBP1A,RPL32,CCAR1,TLR8,TMCC2,ING2,POLE4,CDC26,RANBP10,SERTAD3,CH25H,MYO1B,DUOXA2,VIPAS39,CCIN,RPS11,CTTNBP2NL,IDH1,B3GALNT1,ASB11,KCNG3,TRAPPC1,BRD9,TBC1D17,VXN,SOCS2,PTPN4,RNF39,SELENOP,GON7,TPBG,BOLA1,AKAP8L,ZNF770,ZNF622,ZC3H7A,RPL4,TOP1,UBXN2B,ACTMAP,GPT,RETSAT,TBC1D24,ZMYM2,HNRNPD,SHOC2,LILRA3,MAP2K1,KHDC1,PLEKHF1,RAB8B,SERPIND1,PPME1,RPS2,RNF167,ISG20,TMED3,KBTBD6,CTSD,METTL14,CDO1,TRAFD1,CTNNA1,STRBP,VTA1,GCC1,EIF2B5,ARHGAP21,MTMR2,PHF1,DIPK1A,ZDHHC14,ETFB,TAF10,CCT8,TGFB1I1,EMC8,FADS2,DPP4,MLF2,LDOC1,CTSA,TMEM59L,NECAP1,ZSWIM7,ZMYM6,SPOP,IFNAR1,RIGI,PPP3R2,USP15,PSMB6,TRAPPC13,TAB2,TMEM106B,MAPRE2,STOX2,ZNF821,CLPX,ANKRD6,VKORC1L1,LSM5,NFYA,PGR,OST4,ATF1,FAM53C,FAR2,RPS27A,ABHD17A,LYSET,PAFAH1B1,NKIRAS2,FAM89B,ARPC2,ATP5MG,RBFOX3,ERLEC1,PWP2,ARPC3,GCA,CSRP1,FAM91A1,PAIP2B,RXRG,CRYBA1,TNFAIP6,CEND1,TWNK,ZNF177,WSCD1,BEND6,MAPRE1,SETD5,TRIM62,ASPM,SFN,PNP,ASTN1,HADH,BIRC2,NCAPG2,STBD1,CBX3,SPON1,FLRT3,HAS3,TBC1D25,PSEN2,RTF2,TOP3B,PML,ILVBL,USP14,KARS1,TMUB1,AKR1C1,SPRN,KRR1,COX6B2,ZSCAN25,GSTP1,GPAM,CYP4F12,MRPL57,EIF4E2,DNAJC25,ZNF687,NUDCD3,PRNP,CEBPG,GTF2F1,EXOSC3,BCL10,ABHD13,EPS8,FAM210A,HOXB8,CLVS1,FRMD8,ZNF22,CYTH2,TIMM8B,TMEM179B,NEFL,IGF1,TRIM36,ZFP64,RETREG3,PIK3CA,EEF1A1,NPC2,GDAP1L1,NFE2L2,KLF10,TLDC2,TUBB,RNF115,RAB11A,RGMB,EMC6,IPO8,STT3A,RAB28,DUSP26,PSMA2,GIMAP2,UFM1,ACBD6,MAD2L2,TRMT61A,RPS4X,CPSF2,PSMD4,NPY,HYPK,RILPL2,CUL2,EDF1,CIDEB,NXT1,INO80C,MYORG,RFC2,GABRG2,KIAA1191,RPL39,STK26,STAR,NONO,PRDX3,CD209,NEURL2,MEF2C,TRA2A,BOLL,GGCT,GAS8,PYCARD,TMEM100,CDH13,PPM1M,BNIP3L,MAVS,MZB1,CBR4,TBCEL,FAM8A1,ARHGAP15,POLR1H,FHIT,EIF2AK2,PXMP2,RAPGEF5,NDUFC2,PQBP1,PDIA3,TRMT1L,FMOD,MRPL34,DBH,IL13,CYP17A1,GLIPR1,STARD7,PAFAH1B2,ZCCHC12,CDNF,PPP2R2C,FBXO3,NUFIP2,SRSF7,AZIN1,G3BP1,ARHGAP5,EIF3G,ILF2,SEC61G,NDUFB7,CNTROB,ZCCHC7,SRFBP1,TBC1D13,YPEL4,GPBP1L1,ELOVL7,ST3GAL5,ST8SIA4,COA4,MED11,TFRC,MAEL,CSRNP3,SNX10,ZC3H11A,CHMP4C,PSME2,TRAF7,KLK5,HBA1,ITGB5,FBXO9,PBLD,TMEM126B,HECW1,COQ10B,LBR,MBD3,FGF17,OVOL1,PSMB1,ATP6V1C1,NAA30,AIPL1,TIMM21,PPARA,WNT2,BAG3,LINC02914,TUSC2,CACNB4,AQP4,ATOSB,FLRT2,RETREG1,IMPACT,HEXB,BST2,CYP11B1,MRPL36,SCG3,DLX1,GCNT3,CALY,RGL2,F7,GALNT1,TMEM33,GAPT,ARMC1,PTN,NAA35,UQCRC2,TAPBP,NEK2,SLC66A2,NLRP3,RAB5A,UBTD2,SESTD1,EIF3D,TNFAIP8,NGB,PKIA,MRPL47,CCR3,TRIM27,GNB3,ALG2,FAH,FBP2,NOVA1,PPWD1,PCMTD2,RNF139,ZNF343,SMAD2,SLC1A3,MYH1,KANSL3,CREG2,KLHL1,CCT2,NGRN,DET1,LRP6,CYBRD1,LCP1,SELENOS,GEMIN8,RPL15,DNPH1,RPS20,PTPN5,PDP2,DDT,RRM1,LRRC8A,CTDSPL2,DUSP21,TMEM106C,YWHAH,WDR45,NR4A2,CENPM,HLF,DPM2,AOX1,MED13L,RAC2,KLHL7,COPS7A,FAM83B,MYOZ3,PMP2,PAFAH1B3,NUDT12,SGMS1,TRIM8,PAQR3,OSBPL8,ARMC6,LAMP3,LSM2,GSTM4,PDE9A,FCGR1A,CRIP1,VPS4A,LIMD2,CTDSP2,ISX,CPSF4,RGN,EGR1,DBR1,VPS39,ARHGAP1,DUSP10,RNF187,NCBP2,CCNH,UST,FAM241A,FCMR,LDB2,RPL9,GDE1,DENND2D,TRIP4,SRPK2,KRIT1,NDUFS3,DNAJC30,CTBP1,HIGD1C,TMEM174,DDAH2,NR1I3,ZNF692,CIBAR1,PHYHIP,ARMCX3,HAX1,PPP2R1A,PROM1,ANP32A,NDUFAF3,RHOB,PDHA1,DDRGK1,RSBN1L,DTWD2,TAF7,GNPTG,CMC1,PRMT5,CDK5R1,KLF4,SKA2,HELLS,DDIT4,OTULINL,DHPS,UBE2I,ADCK1,EIF2S1,NUDT1,ROCK1,RHBG,PAK2,PHC1,ZBTB38,ANKRD49,CRHR1,F2,TPT1,SNX12,MMADHC,MCCD1,SURF4,DHX9,CHI3L1,UBAP1,PIP5K1A,TRUB1,MAP1LC3A,TMED7,CASP12,CATSPERZ,FBP1,SPTSSA,CGRRF1,EXOC8,VAMP3,KLHL3,TLR1,SAP30,TRIM10,SMARCE1,MRPS11,PRCP,DMPK,ENO2,ACTL9,ISOC1,SPSB3,LIX1,LEPROTL1,S100A11,HSDL2,CDCA7L,SAR1B,DRG2,RPL17,PIK3R2,LSM8,CLDN8,TXNL1,SLC25A51,KDELR2,SIRT7,TRIM52,CREB3L4,HAPSTR1,CXXC5,CTSK,CHST7,PSMD10,EIF4A3,WSB1,SV2B,SPOCK1,MNAT1,AKR1B1,PLCXD3,IFI35,RNF126,EGR2,FAM241B,RFXANK,STAT5A,GSTM5,RWDD3,RPLP1,NAA50,DYNLT3,RAP2A,RAB3C,RNASEH2C,GPSM3,RELL1,SPMIP6,SAV1,ISCA2,SNRPD2,GNMT,UBE2D3,STOM,ZBTB18,ADSS2,CPT1B,CSGALNACT1,JAGN1,SLC25A39,MTX2,APOC2,SMCP,MED23,PIK3CG,REEP3,RNF14,CAV3,CFAP61,TMEM177,PSPC1,LANCL1,PITPNA,FAM76B,YIF1A,HENMT1,PYURF,NICN1,RHEB,FOXC2,ADIG,ZNF319,MARVELD1,DLG3,INPP4A,GPNMB,PPIG,VPS33A,SPMIP5,IMP4,MAP1LC3B,EMC2,NUDT4,CMKLR2,GLRA2,TAF2,PABPC5,PFDN5,MAGEC2,LRATD1,MSH6,SNRPN,MRPL40,TMBIM1,UBE2H,DNAJC10,TNFSF13,PLEKHO1,CKB,MED29,CACYBP,FAAP100,IMMP2L |
| 1.554e-04 | -8.77 | ARHGEF17 (Rho guanine nucleotide exchange factor 17) | protein interactions | 9828 | 46 | 25 | 19454 | 5460 |
YWHAB,TMOD2,SFN,YWHAG,YWHAH,PRDX2,RPL10L,DYRK1A,ESR2,VIRMA,RASL11A,EFNA3,RTRAF,CAPZA2,ATG16L1,H1-5,WDR83,RASL12,E2F4,TP53,MAP1LC3B,LBR,RERG,PRDX4,BCAP29 |
| 1.555e-04 | -8.77 | mRNA Processing | WikiPathways | WP411 | 132 | 68 | 5310 | 1910 |
PRPF18,SRSF7,CSTF3,HNRNPK,SNRPA,SNRPB,RBM17,CPSF2,TXNL4A,HNRNPA1,SPOP,RBM5,SNRPB2,CSTF2T,DHX38,DNAJC8,DICER1,DHX9,SNRPG,HNRNPAB,CLP1,SRSF4,CLK4,MIR939,SNRNP70,SF3B4,SNRPD1,SRP54,PAPOLA,SF3B1,LSM2,SRSF1,HNRNPA2B1,TRA2B,CLK1,NCBP2,DHX15,MIR636,DDX1,SRPK2,CPSF1,NONO,SNRPE,MIR1234,PRMT2,SUGP1,SNRPA1,CPSF4,DHX16,CD2BP2,PPM1G,CDC40,SF3B5,SNRPD2,HNRNPH2,HNRNPD,SRSF2,SF3A1,SUPT5H,HNRNPC,HNRNPL,PSKH1,MIR7-1,SNRPD3,SNRPN,SNRNP40,SRSF10,PRPF4 |
| 1.555e-04 | -8.77 | negative regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001237 | 100 | 47 | 18204 | 5365 |
CTTN,STRADB,IL7,TERT,NRP1,BCL2L1,LGALS3,AR,MIR221,SNAI2,MIR222,BRCA1,ACVR1,MCL1,CTNNA1,GPX1,MIR142,GSTP1,TNFAIP3,FGF10,ITGA6,IL1A,CX3CL1,ICAM1,RAF1,TNF,PEA15,IGF1,IFI6,EYA3,PAK5,RNF34,TMBIM1,CSF2,PELI3,IL1B,SIAH2,AKT1,SRC,SCG2,PRDX2,RB1CC1,LMNA,ITGAV,ZMYND11,GCLC,FAIM |
| 1.558e-04 | -8.77 | NUDC (nuclear distribution C, dynein complex regulator) | protein interactions | 10726 | 293 | 111 | 19454 | 5460 |
CORO1C,IGBP1,ATXN10,DYNC1I2,CHMP2A,HSP90AB1,PRPF19,GSTM3,VPS26A,XPO1,CTNNB1,SKIC8,RHOG,ARMC8,ZYX,CCT8,DNAJB4,SCPEP1,KRAS,G3BP1,AP1M1,HNRNPDL,COPS4,TUBA1A,EZH2,CPSF1,IFT172,TUBB,TENT5C,FBXO22,PSMB6,PPP5C,ERH,NIBAN2,CUL3,PAPOLA,CUL2,TAFAZZIN,BRCA1,FBXW11,YWHAZ,HSP90AA1,SP1,RIT1,ATP5MK,HSPA8,HDAC5,AKAP1,EP300,YAF2,NUBP2,UFL1,STAU1,CMAS,ATP6V1G1,PAFAH1B1,RND2,DET1,ETF1,PIH1D1,AIFM1,CAMLG,PLEKHF2,EIF2B5,PRNP,LMAN1,CDC5L,KARS1,MOV10,GTF2E1,GAPDH,SLC35A1,FAF1,MAP1B,POC1B,EMC2,HUWE1,DYNC1I1,FKBP8,KBTBD4,GBE1,MTCH2,ACTR1A,ACTR2,PPME1,TSSK1B,CCNF,ENO1,TRIM24,VIRMA,MAT2A,RPS17,SPOP,UBE2H,SOD1,RPA3,BAP1,SLC39A9,PML,CSTB,EXOSC4,MTDH,FBXW7,UGP2,MARS1,WDR5B,MAEL,RPA2,RPRD1B,RARS1,UBE2M |
| 1.559e-04 | -8.77 | Fluid shear stress and atherosclerosis | KEGG pathways | ko05418 | 142 | 70 | 7161 | 2463 |
GSTT2B,SRC,NQO1,MEF2C,IL1R2,SUMO2,SQSTM1,MGST3,ICAM1,VEGFA,NFE2L2,FOS,GSTM3,HSP90AB1,ITGAV,THBD,HMOX2,GSTA2,IFNG,CALML5,TP53,HSP90AA1,ACTB,GSTO1,GSTA4,MEF2A,IL1A,CTNNB1,TXN,GPC1,SDC4,NFKB1,HSP90B1,GSTM5,AKT3,ACVR1,GSTA1,SUMO1,GSTM2,BMPR1B,SUMO3,CAV1,MMP9,CAV3,MAPK10,DUSP1,GSTT1,IKBKB,GSTO2,MGST2,PIK3R1,AKT1,PIK3R2,MAP2K6,RAC2,NPPC,PIK3R3,CAV2,GSTM4,PIK3CA,CCL2,TNF,BMPR1A,BMPR2,IL1B,GSTP1,JUN,AKT2,MIR10A,SDC2 |
| 1.559e-04 | -8.77 | Fluid shear stress and atherosclerosis | KEGG pathways | hsa05418 | 142 | 70 | 7161 | 2463 |
GSTO2,PIK3R1,MGST2,AKT1,PIK3R2,GSTM2,SUMO1,GSTA1,ACVR1,BMPR1B,CAV3,MMP9,CAV1,SUMO3,IKBKB,GSTT1,DUSP1,MAPK10,MIR10A,AKT2,GSTP1,JUN,SDC2,CAV2,PIK3R3,RAC2,NPPC,MAP2K6,GSTM4,TNF,CCL2,PIK3CA,IL1B,BMPR2,BMPR1A,NFE2L2,ITGAV,HSP90AB1,GSTM3,FOS,IFNG,THBD,GSTA2,HMOX2,TP53,CALML5,SRC,NQO1,GSTT2B,IL1R2,MEF2C,SQSTM1,SUMO2,VEGFA,MGST3,ICAM1,CTNNB1,SDC4,GPC1,TXN,HSP90B1,NFKB1,AKT3,GSTM5,HSP90AA1,GSTO1,ACTB,MEF2A,GSTA4,IL1A |
| 1.572e-04 | -8.76 | GPR42 (G protein-coupled receptor 42) | protein interactions | 2866 | 110 | 49 | 19454 | 5460 |
TMBIM6,SLC41A1,TMEM19,SLC38A7,PMP22,ADGRE2,BTN2A2,FXYD6,MFSD5,COMT,RPRM,TMEM237,TSPO2,CXCL9,ANKRD46,NRM,MFSD6,YIPF4,TMEM182,TMEM147,YIF1A,ATP6V0B,ERG28,STX8,RUSF1,ALOX5AP,PAEP,LEPROTL1,TF,ADIPOQ,GPR37L1,TMEM60,NSG1,GJB2,SLC35E4,SLC38A1,SYNGR1,SERINC1,PLP1,EFNA5,SERTM1,CTXN3,CCDC167,GOSR2,DRAM1,FAM3C,SYNDIG1,SMCO4,TEX264 |
| 1.572e-04 | -8.76 | REEP6 (receptor accessory protein 6) | protein interactions | 92840 | 110 | 49 | 19454 | 5460 |
PLP1,CYB5R3,KRTAP3-1,MOG,RETREG3,ODR4,RPS20,KDSR,NTAQ1,PRRT1,GORASP2,SAYSD1,CYB561,REEP6,CXCR4,SNX11,TSPAN15,VIPR1,TMEM185A,SLC35F2,LITAF,TMEM167B,LPAR1,TACR3,IL2RG,TIMMDC1,SDCBP,LMNA,SYS1,COQ8A,CD63,SNX1,TMEM170A,FHIP1B,TLCD4,TMEM208,EMC6,FAM241A,FAM241B,PLSCR1,ATP5PF,UNC50,SLC2A8,PICK1,LEPROTL1,KLRF1,GALNT2,GDE1,SPG21 |
| 1.572e-04 | -8.76 | ARHGAP39 (Rho GTPase activating protein 39) | protein interactions | 80728 | 110 | 49 | 19454 | 5460 |
FKBP4,RHOG,PDIA3,CALR,TPM3,PPIB,LYAR,HNRNPL,CAV1,EGLN3,DKC1,WDR6,PTPN1,RAC2,PDHA1,RPN1,FEN1,ANP32A,PPP2R1A,HSPE1,HMGN4,KRAS,PSMA1,CHCHD2,FLOT1,PRDX4,PCNA,SEPTIN7,RHOB,CKB,CALU,LDHB,MCM3,ST13,PRDX2,VIRMA,ESR2,PSMB6,PSMA6,NFKBIA,GANAB,ATP5PO,PRDX3,CDC42,MRPS7,HSPA5,CNKSR3,GID8,DLAT |
| 1.573e-04 | -8.76 | H2A | smart domains | SM00414 | 19 | 13 | 9717 | 2575 |
H2AC4,H2AC25,H2AC1,H2AJ,H2AZ1,H2AC7,H2AZ2,H2AC14,H2AC6,MACROH2A1,H2AX,MACROH2A2,H2AB1 |
| 1.574e-04 | -8.76 | KLHL20 (kelch like family member 20) | protein interactions | 27252 | 176 | 72 | 19454 | 5460 |
CRMP1,IGF2BP1,CHTOP,IVNS1ABP,MECP2,NTAQ1,PRMT6,HNRNPC,CUL3,SMARCA5,CEP97,CBX5,LRIF1,CSTF3,DAPK1,MACROH2A1,EIF2S2,DOK4,MACROH2A2,UBE2M,UTP15,NUFIP2,CIMIP1,IPP,PICALM,RPRD1B,BCL6,WDR3,SRSF2,TCEA1,PML,PRIM2,PYM1,BCL2L1,SUV39H1,KLHL22,TRA2A,HNRNPA1,XPO1,TMA16,HR,ATG9A,BAZ1B,SLC13A5,NUP35,BUD31,MITF,MIOS,PWP2,KLHL12,STK16,KLHL26,PIR,TNPO2,NUDCD3,LBR,IMP3,STRBP,RBM12,RAD21,MDC1,SSRP1,ENKD1,POLDIP3,DUSP21,NOC4L,NRGN,VRK1,EMC2,ZC3H11A,ERG28,TOP2B |
| 1.579e-04 | -8.75 | Signaling by FGFR2 | REACTOME pathways | R-HSA-5654738 | 75 | 39 | 10285 | 3229 |
FGF16,PIK3R1,FGF7,HNRNPF,FGF1,TIA1,GAB1,HRAS,PPP2CB,POLR2C,FGF23,GTF2F1,POLR2I,PIK3CA,FRS3,FGF3,FGFBP1,SHC1,FGFBP2,SRC,HNRNPA1,FGF10,FGF17,POLR2B,NCBP2,POLR2F,POLR2G,PTPN11,RBFOX2,KRAS,GTF2F2,RPS27A,POLR2D,UBA52,FGF22,POLR2L,PPP2R1A,CBL,UBB |
| 1.595e-04 | -8.74 | axon ensheathment in central nervous system | biological process | GO:0032291 | 26 | 17 | 18204 | 5365 |
CLU,GPM6B,PTEN,MIOS,KCNJ10,MYRF,TLR2,ASPA,CNTN1,NKX6-2,MOBP,ID4,NCSTN,CNTNAP1,PLP1,FA2H,B4GALT6 |
| 1.595e-04 | -8.74 | central nervous system myelination | biological process | GO:0022010 | 26 | 17 | 18204 | 5365 |
CNTN1,ASPA,TLR2,MIOS,KCNJ10,MYRF,GPM6B,PTEN,CLU,FA2H,B4GALT6,PLP1,CNTNAP1,NCSTN,MOBP,ID4,NKX6-2 |
| 1.595e-04 | -8.74 | XAB2 (XPA binding protein 2) | protein interactions | 56949 | 179 | 73 | 19454 | 5460 |
STAU1,NKAPD1,SIRT7,PML,SNRPA,RPA3,EP300,NUP50,MIRLET7I,RPA2,SNRPN,PABPC5,SF3A1,WDR83,MIR34B,RALYL,SNRNP40,SNRPB2,ESR2,VIRMA,EIF4A3,MECP2,UBE2H,ELAVL2,HNRNPC,CUL3,MYC,AR,SNRPB,PRPF31,NUP42,KRAS,TSSC4,CDC40,CTNNBL1,DHX16,AKAP12,SNRPG,SNIP1,SRSF7,BAG2,ZC3H11A,HDAC11,IK,CDK8,NFKBIL1,SNRPE,ILF2,E2F4,TP53,RAF1,SNRPA1,SNRPD3,SUMO2,MAPRE2,TOP1,MIRLET7G,CDC5L,DHX15,EEF1AKMT3,MIR106B,LDLR,SNRNP70,KIAA1143,DDX23,MAGOH,SMAD9,ZCCHC10,PRPF19,IFI16,DDRGK1,HNRNPA1,HSPB8 |
| 1.595e-04 | -8.74 | TEX2 (testis expressed 2) | protein interactions | 55852 | 179 | 73 | 19454 | 5460 |
RAF1,STBD1,DCAKD,CCDC47,FAF2,DNAJC25,STIM1,RPN1,RAB4A,RINT1,TMT1A,RAB13,STX18,BAG2,EMC2,RAB3B,SRPRB,PDRG1,FKBP8,LAMP2,SLC25A46,YWHAH,DDRGK1,ESYT1,DNAJC7,OSBPL8,PTPN1,RAB35,CAMLG,HSD17B11,DNAJC1,LMAN1,SLMAP,TMPO,SEC22B,OTULINL,RND2,FAXC,SEC62,ST7,VAPB,SDC2,USE1,SSR1,UBAC2,LEMD3,RAB5A,RAB9A,RTN4,DERL1,YKT6,EMC1,PXMP2,TOMM20,STX7,TMEM209,PSMB2,VEZT,SFN,RAB11A,MLF2,YWHAZ,FIS1,CNIH4,STUB1,GUCY1B1,GSK3A,SEC61B,COPE,REEP4,UBB,VIRMA,SEC63 |
| 1.599e-04 | -8.74 | CAVIN1 (caveolae associated protein 1) | protein interactions | 284119 | 284 | 108 | 19454 | 5460 |
CRBN,POR,BRD3,KXD1,H2AC14,CSNK2A1,TPM3,EIF2B2,CAV1,PTPN1,RAC2,TNFAIP8L1,GNPDA2,ILF2,ZFP1,NUPR1,SNAP29,FAM162A,SOCS3,THRAP3,TFPT,MAP1B,TCOF1,RPL23A,DHX9,KLHL15,BICD2,CCHCR1,RAB2A,OLFM3,VAMP5,CIAO1,ARHGAP21,ZNF622,RHOJ,DYRK1A,GSK3A,PHAX,MACROH2A1,GOLGA5,GIT2,ATG16L1,UQCRC1,GTF3C4,CDC42,CFTR,KDM1A,HMGB1,OIP5,PPM1G,RHOU,DVL2,SQSTM1,RTN4,RHOG,RAB5C,ZCCHC10,INSYN1,NT5C2,EXOC1,RHOH,NUF2,HMG20A,RPRD1A,RAB35,TNIK,ATP6V1A,COPS2,EZH2,RND3,MAX,RAF1,JUN,TRIM26,PSMA1,KRAS,TRIM37,RPS4X,CDCA7L,RPL31,HECTD3,DCAF4,RHOB,PSMD14,MYC,RAB11A,CAV3,BAG3,CAVIN2,MB21D2,TAX1BP1,SPCS1,KBTBD6,ATP6AP2,BAD,PHF21A,NUP62,PAFAH1B1,RND2,YIPF5,DET1,STAU1,EEF1G,GPC1,SPECC1L,HSPA8,YAF2,RAB5A |
| 1.601e-04 | -8.74 | G-protein activation | REACTOME pathways | R-HSA-202040 | 29 | 19 | 10285 | 3229 |
GNG13,GNB1,OPRM1,GNG3,GNAI3,GNG11,GNG5,GNAO1,GNB4,GNG7,GNG10,GNAI2,GNG12,GNG2,GNAZ,PDYN,MIR197,GNGT2,GNB3 |
| 1.601e-04 | -8.74 | SUZ12 (SUZ12 polycomb repressive complex 2 subunit) | protein interactions | 23512 | 614 | 213 | 19454 | 5460 |
NUP35,SRSF10,ZNF593,ERLIN1,CCAR2,NOP58,HP1BP3,PHB1,THOC2,SKIC8,DDX23,ZNF207,TRA2A,DPY30,STOML2,HMGA1,PRDX1,PRPF19,PDIA3,SSRP1,RAD21,TRIM37,RBBP7,ZNF592,SRSF7,SRSF8,FHL3,SLC39A7,PCNA,RBPJ,EZH2,SAP30,ERH,CHCHD3,MED17,RBBP4,EIF4A2,SNRPD2,SNRPD1,RAN,BRCA1,FYTTD1,MCM4,RBM15B,PYCR1,CFAP20,G3BP2,SKP1,CSRP1,IL1A,IL1B,NUP50,UPF3B,MYL6,MFAP1,ARMCX3,ATP5PO,WDR77,CWC15,ZBTB2,MDM2,NCBP2,TOP1,METTL6,MYBL2,KRR1,SMAD3,AIFM1,H2AZ1,EPOP,SPP1,NFKB1,CALR,ARF4,VRK1,BACH1,THRAP3,BSCL2,NKRF,SFXN1,ILF2,EXOSC8,MTA3,VIRMA,CEP97,UBB,UBE2I,EZH1,CTNNA1,EIF4A3,CCNF,MAPRE1,SDF2L1,PPP1CC,TUFM,AR,SS18,POLDIP2,NHP2,MBD3,NUCKS1,SMC4,GTF2I,RPA3,ARMCX1,MACROH2A2,EIF3J,ELP3,SNRPN,SF3A1,HMG20A,SNRPD3,SNRPA1,EED,RBM5,FUBP3,SRSF1,SIN3A,MAGOH,POU5F1,NGDN,PPIB,CBLL1,CDCA7L,RUVBL2,TRIM21,EWSR1,MTA2,SMARCB1,H2BC1,H1-3,TRMT1L,ESR2,POLR2B,MORC4,CBX5,SNRNP40,ATP5F1B,USP16,SF3B4,THOC6,RCL1,H1-1,FBXW11,H1-10,CHTOP,UFD1,MLF2,LDHB,MYC,SAP18,PHB2,TRA2B,FXR2,DDX5,RTL9,SF3B1,XRCC5,CCDC9B,DDX39B,PYM1,SNRPA,FAM81A,ZC3H14,CDC5L,DKC1,BRMS1L,SHPRH,RPS16,CAND1,PLG,UBE2N,ALYREF,AKAP8L,SNRNP70,H2AC4,ABHD16B,USP3,PHF1,KPNA2,CSE1L,CDC40,H3C1,NUP107,DHX9,SLC25A11,RBM34,NEFL,NECAP1,CDK8,CBX3,H2AX,TP53,BUB3,MACROH2A1,KIAA1958,CSNK2B,EIF2S2,ZNF330,LIG3,SF3B6,CREB1,RC3H2,SMARCA5,RBM22,PML,ACACA,LUC7L3,UTP15,SAMM50,ZNF326,GTF3C4,PPP1R8 |
| 1.602e-04 | -8.74 | PICK1 (protein interacting with PRKCA 1) | protein interactions | 9463 | 477 | 170 | 19454 | 5460 |
GTF2E2,JUN,GFI1,OARD1,TOP3B,DCUN1D5,MOB3C,APTX,SSBP3,SMARCB1,TLNRD1,FBXL3,SCAND1,EFNB1,BLOC1S2,PICK1,AKT2,RFC3,PAX6,ENKD1,CDCA7L,AP1M1,SSNA1,PSMA1,ZBED1,EIF3D,STK4,CTNNB1,DNTTIP1,INO80E,HMBS,CEP57L1,FAM219B,RXRG,HMG20A,CEP19,ZNF593,PRPF18,CGGBP1,BUD31,SNRPA1,ASIC1,ZNF576,LMO3,ISCU,GPC4,TANK,FGF16,EHHADH,NDE1,SSBP2,NCOA5,THAP6,GRIK1,CDC42EP2,ATP5IF1,HSDL1,GRXCR1,BOLA3,PEBP1,COIL,LZTFL1,FXR2,NPTN,TTC23,DRAP1,THAP7,LDB1,PRPF31,GRB10,CDKN2D,ZNF250,GTPBP2,ICA1,FAS,ZMAT2,ATXN1L,DLG4,DPEP1,MTG1,SCNM1,TRIM44,ARF1,AVPI1,GRIA1,SNRPB2,ATP6AP2,GPR37,TSN,RIMS3,IP6K1,PPARA,TBK1,MSRB3,RNF181,RNF8,UGCG,ILF2,MAGEA4,SLC6A3,CPNE2,KLHL24,TCEA2,EIF1AD,RPIA,NOC4L,POLL,SERTAD1,CHMP1B,SSBP4,ZNF24,USP2,TCEANC2,ZNF575,ASIC2,MAP2K6,MGME1,ITGA6,WDCP,EEF2KMT,ZBTB2,ILVBL,GNPTG,CCNH,FAM161A,TFIP11,PRKCA,SH3GLB2,ARL15,DCTD,BTG2,RPA2,ITGA2,ARFIP1,MNS1,PNO1,GRIA2,ARMCX1,MBD3,UBE2K,PCBD1,PRKACB,RUNX1,TYW3,MORF4L1,LRRC73,AKT1,REEP6,FXN,BAHD1,CDC73,SERTAD3,ATOSB,UBE2E3,AMIGO1,PTEN,HEXIM2,EIF4A3,PAFAH1B3,NECTIN2,ZNF330,OPTN,PDCD5,RPP25,CYP21A2,YES1,EIF4H,F11R,TRIM54,KCTD9 |
| 1.605e-04 | -8.74 | Selenium Metabolism and Selenoproteins | WikiPathways | WP28 | 46 | 29 | 5310 | 1910 |
DIO3,SELENOS,SEPHS2,NFKB1,SELENOI,SELENOP,SP1,SELENON,SELENOM,SELENOK,SEPHS1,SELENOV,JUN,SELENOT,GPX1,GPX3,DIO1,SELENOO,TXNRD3,TXNRD1,GPX6,TXNRD2,MSRB1,SELENOW,GPX2,NFE2L2,GPX4,FOS,DIO2 |
| 1.607e-04 | -8.74 | positive regulation of developmental process | biological process | GO:0051094 | 1385 | 468 | 18204 | 5365 |
LRTM2,EEIG1,CCL19,LRRN1,PIAS1,MIR378A,TRIB1,XRCC5,SYCE3,NINJ1,RARRES2,TLR2,AGGF1,NLGN2,TRAF6,FXR2,MIR222,CYP1B1,IL15RA,NFKB1,TERT,BMPR1B,NPPC,IL2RA,HCLS1,FOS,DISC1,CHI3L1,JMJD8,MAPKAPK5,NME2,TESC,NOG,HDAC6,STK11,PITHD1,SYK,PROM1,MACROH2A2,SAV1,ACVR1B,KLF10,CD40,CCN3,TRIM32,WNT2,GPAM,CYB5D2,KMT5B,RAP1A,SLITRK2,SLC23A2,TFRC,VSIR,SMAD3,PARP2,ATRAID,FLRT2,NTRK2,STIM1,NIBAN2,LMO3,CAPN2,ADIG,CCDC3,FZD4,CTNNBIP1,BLOC1S5,SHOC2,CAMK1,SLC6A6,NR2E1,BRMS1,AMIGO1,BMPR2,IL23A,SEMA7A,TFE3,VEGFA,NF2,MIR29A,EXOSC3,HSPB6,MIR137,NFE2L2,IL15,BMPR1A,SLITRK1,MECP2,SMARCB1,LLPH,UTP25,MIR140,ATF4,WIF1,LEP,TNFSF12,IL18,DAG1,SRC,OLFM2,CAMP,LGR4,MIR143,SYT2,PAFAH1B1,TIAM1,ZC4H2,NLGN1,IFNG,SS18,CCND1,MIR130A,MIR221,MIRLET7B,TGFBR2,IL2,PLAA,SLC8A1,RND2,AR,TNFSF13,XBP1,MIR206,KIT,FLRT3,RLN2,DVL2,L1CAM,BAD,CD34,JAK2,FGF1,MIR125A,VLDLR,STAT1,NRP1,PLA2G5,PRMT5,AGR2,AMELX,GPC1,SMAD4,ELAVL4,VSTM2A,PPP3CA,WNT7A,AKT1,BMP1,TGFB3,IL1B,CTNNB1,RBBP4,GH1,MAP1B,VDR,SHLD1,CCL24,TOX,OXTR,RALA,RETN,IGF1,SAP30,EP300,BRD9,DIO3,ASPA,CPNE1,MSX2,SFN,SYT4,ANAPC2,MIR21,MIR30B,MIR519D,PLCB1,TLR9,SMARCD3,TNFRSF1B,ADM2,RTN4,MIR548C,EMP2,SMURF1,GPRASP3,ZBTB16,ELAPOR2,RGCC,GLIPR2,JAK1,CREBL2,MIR210,CD80,CD36,MAD2L2,SSBP3,PAX6,SIN3A,MIR204,WNT10B,FOXS1,SPRY1,HAX1,NEUROD2,SMARCE1,EMC10,FLOT1,KLHL25,VEGFC,OTX2,JUNB,ACTL6A,PRL,PNP,PLXNC1,AKT3,FOXP3,MIR1224,FUT1,BAX,IL6,HAPLN2,SLITRK5,ID4,CD86,BTG1,ASPM,MIEF1,CXCL9,LRRTM1,GPM6B,TMEM100,MIR185,IL12B,MMP14,FOXC2,BCL7C,RHOH,NEFL,CFTR,PRKCA,GJA1,ZHX3,MIR17,MIR214,NLRP3,ACVR1,ASIC2,ILK,RAG1,MIR424,ZNF365,LRRC4B,RB1,ADNP,TBC1D24,EMILIN1,ITGB8,CXCR4,AGER,LRRC24,ZNF304,RHOB,IL1RAP,TAPT1,DUSP10,CORO1C,HMGB1,BCL7B,MME,DDAH1,KCTD11,BCL6,CXCL12,NKX6-2,TESPA1,MSX1,CX3CR1,MIR145,LRRTM2,ING1,TMEM106B,CCR3,ACTB,TNF,ADIPOQ,RBBP7,LBH,CX3CL1,BRMS1L,IL10,MUL1,RBPJ,SP1,UFL1,PPARG,CLSTN3,MIR30A,SFRP4,TSPO,GAB1,IMPACT,F11R,STK24,JUP,MIR106A,ZNHIT1,FAXDC2,MIRLET7G,IL7,CHRNA7,UPF3B,EZH2,LGALS3,S100B,EPO,TPBG,HMCES,CYP27B1,IL34,MYRF,TGFB1I1,MKKS,KLF4,CCL11,ZBED3,MIR590,APLNR,DLG4,LRRC8A,FGFR1,NKAP,MIR99B,CRABP2,BRINP2,LAMB2,GHR,AAMDC,PPIB,MIR1-1,CLEC7A,SOD2,MIR34A,IL13,EHD1,BRINP1,SDCBP,ACTL6B,MIR133B,LPAR1,MDM2,CXCL8,STK4,SNAI2,FIS1,DICER1,CBLN1,BRINP3,ADAMTS20,MIR20A,GHRL,FZD3,SOX9,RHEB,LTA,SAP30L,PPP1CC,CCR1,PRKCB,MIR511,MAP2K1,SETD3,IL5,MIR200C,SMAD1,MMD,KDM1A,MACROH2A1,SEMA5A,STAT6,ISG15,MTDH,PROX1,ADRB2,GREM1,SOX2,DKK1,FAM20C,FGF10,ADD1,IL2RG,MIR9-1,NOTCH2,KRAS,SLC6A3,IL1A,TGFB2,LRP3,CD46,CBLN2,IGFBP3,CD4,PTN,MIR146A,PSEN1,EGR2,MTM1,LILRB4,BEND6,MIR208A,RUNX1,SOCS5,SMAD2,MIR342,NPTN,BRCA1,IL4,MIR31,FKBP1B,CBFB,CMA1,HSP90AB1,PTPRZ1,CD28,MEF2C,MIR150,EFNA5,ING2,CAV3,SOCS3,TYROBP,CSF2,BTN2A2,SMAD5,IL6ST,HEY2,SYNDIG1,TGIF2,MTCH2,OPRM1,CFL1,STK3,FRZB,SASH3,CD83,MIR132,HTR2A,CDK1,MARCHF5,OSR2,MYC,FERMT2,SFRP1,IGF1R,CREB1,MIR126,SLC20A2,CDC20,HSPB1,MIR142,LRRTM3,SOCS2,ZNF322,ZDHHC15,TLR3,EPHA4,DLX1 |
| 1.611e-04 | -8.73 | HMGA2 (high mobility group AT-hook 2) | protein interactions | 8091 | 127 | 55 | 19454 | 5460 |
SMAD1,TP53,ZNF263,EZH2,CHAMP1,CBX3,SSRP1,MDC1,H2AC6,VRK1,RBCK1,H3C1,CTNNB1,E4F1,CSNK2A1,ZNF24,NFKB1,H2AC14,SMAD9,POU5F1,RB1,SMAD3,SYNCRIP,SP2,MDM2,TMPO,TOP1,ETF1,NFYB,H1-5,PSMC4,PRKCA,CDK1,JUP,HSPA8,XRCC5,HMGB1,GTF2I,ARHGAP21,PRMT6,NFYA,MYC,CSK,SMAD2,EPHA2,LMNB1,MACROH2A1,PSMC5,CDC7,DLST,LIG3,PARP2,CREB1,APEX1,SMAD5 |
| 1.611e-04 | -8.73 | AHR (aryl hydrocarbon receptor) | protein interactions | 196 | 127 | 55 | 19454 | 5460 |
CHMP1A,QRSL1,UBLCP1,EIF3J,PSMC4,TRIM52,UCHL3,EMG1,EP300,ANAPC16,HSPA8,SP1,HSP90AA1,ICAM1,STK24,IVNS1ABP,BRCA1,AR,CUL3,SRC,VIRMA,ROCK1,RAB14,ZNF622,PSMD4,GTF2F2,GTF2F1,PPM1M,STUB1,PSMC3,NFE2L2,NAA15,RAF1,RWDD4,PTGES3,UTP25,ROCK2,VRK1,NEDD8,PPP1R12A,CYP1B1,TAF9,SMAD4,BTF3L4,SUV39H1,CTNNB1,XPO1,COPS5,HSPB8,TAF7,CMSS1,PSMD3,EGLN3,RB1,AIP |
| 1.611e-04 | -8.73 | ARFIP1 (ADP ribosylation factor interacting protein 1) | protein interactions | 27236 | 127 | 55 | 19454 | 5460 |
RPA3,RAB5A,RAB9A,HSPA8,PAFAH1B2,TUSC2,STX7,BET1,SHMT1,ATP6V1C1,CNPY3,RPA2,ADSS2,HAUS2,AKR1A1,ARF1,CEP41,ACTB,IDE,RAB11A,GFUS,RAB2A,USP14,RHOB,DESI2,SMPD2,TFDP2,LAMTOR1,PSMG3,DNAJB6,TMT1A,BAG2,PICK1,HSD17B8,CLPB,RAB3B,GIMAP2,ARF4,LYPLA1,KBTBD4,PGM2L1,RAB4A,SYNGR3,RPRM,RAB35,ARF6,G6PD,CDC5L,RAB5C,LAMP2,ATG9A,LAMP3,SMAD4,TSNAX,PPP3CA |
| 1.615e-04 | -8.73 | TNFAIP3 (TNF alpha induced protein 3) | protein interactions | 7128 | 182 | 74 | 19454 | 5460 |
TRIM8,RNF14,NFKB1,UBXN6,GAS8,CTNNB1,YWHAH,YWHAG,TRAF6,BECN1,IKBKB,UBE2D1,GSTO1,BCL10,YWHAB,UBE2N,ACSL4,DIPK2A,KCTD10,TP53,TBK1,TOP3B,TRAF2,AZI2,FBXO3,VRK1,RBCK1,PELI1,G3BP1,TNF,TICAM1,MCM6,CUL3,AKT1,CSK,TNFAIP3,RIOK2,TLR9,TRIM23,STK24,YWHAZ,HSP90AA1,SLC7A11,CCDC90B,OPTN,RPS20,TAX1BP1,STAT1,GNAI2,VIRMA,TRAF1,APEX1,SRC,UBB,TANK,NEK7,GALNT1,GIT2,TRIM3,LRRC69,TBC1D24,ARRDC3,RLIM,SQSTM1,BIRC2,TRIM5,TIFA,IRF7,TTR,RPS15,RNF5,TNFSF10,FABP4,RNF11 |
| 1.624e-04 | -8.73 | PSMG3 (proteasome assembly chaperone 3) | protein interactions | 84262 | 99 | 45 | 19454 | 5460 |
ARFIP1,PSMG4,AMACR,RPP21,PSMB3,ATP6V1C1,PSMC4,SOST,FOXS1,MRPS34,PSMB7,ZMAT5,PSMA6,AVPI1,NMI,PSMD6,THAP8,PSMD1,PSMA4,RIT1,POMP,PSME1,NDUFB5,CA10,APBB3,RASL10B,PSMA5,KRAS,PSMA1,PSMA2,SEM1,PSMB9,IMP3,ZNHIT1,CCDC69,PSMC3,MRPL51,RPS11,PSMB1,CYP27B1,PSMB5,PSMB4,RPL35A,VPS26A,PSMG2 |
| 1.628e-04 | -8.72 | CXCL10 (C-X-C motif chemokine ligand 10) | protein interactions | 3627 | 27 | 17 | 19454 | 5460 |
IRF3,CXCL14,EP300,CXCL9,CXCL11,CXCL10,CCL8,CXCR3,CCR3,CXCL12,XCL1,DPP4,CSK,CCL28,CCL11,CCL5,CCL21 |
| 1.634e-04 | -8.72 | MRPL10 (mitochondrial ribosomal protein L10) | protein interactions | 124995 | 185 | 75 | 19454 | 5460 |
MRPL24,MALSU1,MRPL50,GATD3,MRPS26,SNRNP70,MRPL18,SKIC8,DDRGK1,KLHL22,MRPL9,HNRNPA1,RPL6,GRSF1,MTRF1,IMMP2L,PSMD12,MRPL22,KRAS,COX8A,MRPS11,HINT2,HSPD1,PREPL,MRPL52,KLHL12,MRPL49,MRPL51,MRPL33,GFM2,PDHA1,MRPL36,METTL15,BCS1L,AURKAIP1,MRPL47,MRPL11,RANBP1,RPL19,RPL10,ESR2,MRPL23,MRPL13,TACO1,PNMA1,MRPL53,RIT1,UBE2H,RC3H2,TAFAZZIN,TUFM,MRPL16,PMPCA,MYC,AUH,MTG2,ABCC2,MRPL20,MRPL41,MRPL57,MRPL40,UFL1,HSCB,MRPL17,GFM1,MRPL34,PGK1,EXD2,NGRN,SLC25A3,MTRES1,MRPS18A,RBMS2,MRPL12,MRPL10 |
| 1.637e-04 | -8.72 | ARHGEF10L (Rho guanine nucleotide exchange factor 10 like) | protein interactions | 55160 | 64 | 32 | 19454 | 5460 |
HP1BP3,PSPC1,RPRD1A,SRPRA,CHCHD3,CDK9,NOP58,CAND1,DRAP1,QPCTL,FEM1B,CFL1,STOML2,DDX50,SERPINH1,COP1,GLOD4,LSM12,NDUFA4,SFXN1,PTGES3,BRIX1,NHP2,RPS27A,SSR3,RUVBL1,CSE1L,WASL,SRPRB,TOP3B,ARCN1,CCR1 |
| 1.637e-04 | -8.72 | RAD52 (RAD52 homolog, DNA repair protein) | protein interactions | 5893 | 64 | 32 | 19454 | 5460 |
SUMO1,ARFGAP1,DDX39A,EEF1A1,TUBA1A,LMNA,RPA2,ATP5PO,HSPD1,RPA3,HSPA8,EEF1G,SEM1,LDHB,SEC13,PRDX1,ERCC3,MCM3,GAPDH,BRCA1,YWHAZ,CKB,MAP4,HSP90AA1,RDM1,ENO1,UBE2I,ACTB,PRDX2,HNRNPL,RPS10,PPIA |
| 1.649e-04 | -8.71 | regulation of cell cycle G1/S phase transition | biological process | GO:1902806 | 211 | 87 | 18204 | 5365 |
CDKN1B,MIR193A,MIR214,CCNH,PLCB1,MIR208A,SMARCD3,MIR222,ACVR1,RGCC,PSME1,GPNMB,MIR221,MIR503,AIF1,MLF1,LSM10,CTDSP1,CCND1,MIR519D,ECD,DLG1,RPS27L,PSME2,CYP1A1,CDK7,BCL7C,CDC73,FBXO7,MIR638,PTEN,MIR29C,MIR137,CCL2,ATP2B4,MNAT1,MEPCE,CDKN1A,RRM1,SMARCB1,PML,CACNB4,MIR16-1,PRMT2,TERT,ZNF655,CRADD,CDKN2D,DCUN1D3,PAGR1,RB1,EZH2,MIR29A,SOX2,FAM107A,MIR495,BCL7B,ACTL6A,AKT1,BTN2A2,FBXW7,MIR10A,KLF4,PHB2,RPL26,JADE1,CTDSP2,SMARCE1,MDM2,CRLF3,MIR873,DDRGK1,ACTB,MIR133B,ACTL6B,CDK2AP2,TCIM,TP53,UBE2E2,FBXO31,FGF10,CDKN2C,TMEM14B,RPA2,CCND3,MIR15A,ADAMTS1 |
| 1.659e-04 | -8.70 | NELFB (negative elongation factor complex member B) | protein interactions | 25920 | 113 | 50 | 19454 | 5460 |
ATG16L1,HCST,EIF2B3,RPA2,FOS,RPA3,RFC4,COIL,RUNX1,TOMM40,BRCA1,YWHAZ,KIAA1191,RIT1,NTRK3,ATP1A1,S100A6,POLR2F,CEBPE,ESR2,POLR2B,CENPM,SUPT5H,JUN,RPN1,MOB3C,POLR2C,ILF2,CCT8,ABCF1,DHX9,RPL23A,H3C1,KRAS,SSRP1,WWP2,YWHAH,YWHAG,ELP6,YWHAB,DDX1,ARL10,SRSF1,CD274,SYNCRIP,FABP5,PRNP,POLR2I,EIF2B2,KCTD10 |
| 1.661e-04 | -8.70 | IRF | smart domains | SM00348 | 9 | 8 | 9717 | 2575 |
IRF4,IRF9,IRF6,IRF7,IRF2,IRF3,IRF8,IRF1 |
| 1.662e-04 | -8.70 | negative regulation of catabolic process | biological process | GO:0009895 | 354 | 136 | 18204 | 5365 |
TRAF2,SEC22B,TAF9,HNRNPD,PHB1,LAMP3,MT3,TNF,EP300,DKC1,DDRGK1,SVIP,ATRAID,IL10,SMAD3,RNF5,HDAC6,FBP1,DDIT4,RPS7,POLDIP2,CCAR2,SMAD4,DFFA,PTPN22,ELAVL4,BOLL,IL1B,DHX9,NOP53,HFE,AKT1,GSK3A,CDK5RAP3,HNRNPC,DEDD,DAP,PABPC1,MAD2L1,PHF23,USP14,IGF2BP1,TENT5C,ATP2B4,TIRAP,PML,TMEM39A,MIRLET7B,TRIM63,BECN1,HCAR1,CNR1,FEZ1,VIP,HNRNPAB,HNRNPA0,MET,CIRBP,CSNK2A1,RGN,SNX12,AZIN1,STK38L,AZIN2,FLCN,IER3,TRAF3IP2,EIF4E,ROCK1,TIMP3,USP38,PHAX,CAMLG,USP30,NUPR1,PAIP1,FHIT,LEPR,RRAGA,PIK3CA,THRAP3,TENT2,CST3,TP53,TAB2,TENT5D,ETFBKMT,LEP,TRIM27,RNF41,PIK3CG,TENT4A,PPARA,NRDE2,MTMR2,TIMP4,ADORA1,ADRA1A,HP,HSP90AB1,AGAP2,CTSA,USP5,LYPLA1,ZCCHC17,IREB2,TIMP1,WDR6,CPTP,PRMT6,MAD2L2,RRAGB,FURIN,USP8,AQP11,SCFD1,SNRNP70,PSEN1,MIR146A,RPL23,SGTA,MTM1,MIR21,RGP1,KLHL22,OPHN1,TSPO,GABARAPL2,NQO1,FMC1,SUFU,MCL1,BSCL2,MYD88,SYNCRIP,SNX3 |
| 1.666e-04 | -8.70 | PEX5 (peroxisomal biogenesis factor 5) | protein interactions | 5830 | 191 | 77 | 19454 | 5460 |
GSTK1,LDHB,CUL3,FBXO7,FAS,FTSJ3,BRCA1,STK11,FIS1,ACOX1,S100A6,RMDN3,AP2M1,GSK3A,POLR3H,TRIM24,NUDT7,RANBP6,MGST3,NDN,TECR,IDE,ATG16L1,TOMM22,TIMMDC1,MPV17,PRR13,PAOX,EHHADH,CRAT,DHRS4,NUDT3,RPA2,NUFIP2,RPA3,EXD2,AMACR,SQSTM1,MAVS,TOMM20,PXMP2,PEX26,ACOT8,MOV10,KXD1,USP2,MARCHF5,XPO1,ATG7,SNAP91,PEX3,ANKRD50,PEX5L,PTPN1,DECR2,CACNB3,GNPAT,KRT8,PEX13,PHYH,COX14,HSDL2,MTCH2,TOMM7,KIAA0408,NUDT19,MAD2L1BP,PTRH2,CRELD1,CSTPP1,IDH1,PSMA2,ERLEC1,TRIM37,IFNG,RIGI,FKBP8 |
| 1.670e-04 | -8.70 | HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U like 2) | protein interactions | 221092 | 266 | 102 | 19454 | 5460 |
TMOD3,SRPK2,EIF2AK2,GCFC2,PSPC1,PHAX,RC3H2,CASC3,CDKN2AIP,UBE2H,MAPRE1,RBM7,IGF2BP1,ELAVL2,ATP1A1,CSK,AR,AATF,HSPA5,RNF113A,HNRNPH2,CWF19L1,ZNF326,RPL26L1,TFIP11,RPS14,CDC42,TOP1,CAND1,RPL35A,CDC5L,SLC25A17,RBM42,MRPS9,SYNCRIP,SDHB,PRR3,SNRNP70,MOV10,COPS5,CDC40,MDC1,MEPCE,SRSF12,SNIP1,DHX9,HSD17B10,ZC3H11A,NUPR1,ILF2,TP53,TNRC6C,STRBP,ESS2,H2AX,APOBEC3D,RBBP4,SNRNP40,MATR3,ESR2,BRCA1,FBXW11,CUL3,HNRNPC,APOBEC3B,MYC,SNRPB,AK3,PSMD1,DDX39B,SNRPA,NGRN,CRYAB,FOXS1,ZC3H14,UBL3,WDR77,DUSP14,RND2,RHOH,HNRNPL,RAB11B,RMND1,PHB1,EED,DROSHA,TRA2A,HNRNPA1,RBBP7,SSRP1,MRPS17,HNRNPA2B1,SRSF8,PDHA1,EZH2,SKA3,RHOBTB1,RPL18,RPS11,FAM136A,ERLIN2,SOX2 |
| 1.672e-04 | -8.70 | positive regulation of mRNA catabolic process | biological process | GO:0061014 | 194 | 81 | 18204 | 5365 |
RC3H2,MIR708,CNOT7,MIR423,MIR204,MIR181C,MIR125A,MIR137,MIR200C,EXOSC3,PABPC1,MIR424,MIR491,MIR16-1,MIR210,MIR195,YTHDF2,ALKBH5,MIR373,MIR106A,MIR206,MIR342,FXR2,DCP2,MIR214,MIR320A,MIR20A,MIR193A,MIR100,MIR181D,BTG2,MIR625,METTL14,CNOT6,MIR146A,MIR519D,MIR497,MIR30B,MIR96,MIRLET7B,MIR212,MIRLET7C,MIR130A,MIR149,MIR192,ROCK2,MIR24-1,MIR185,MIR223,CNOT2,MIR106B,MIR34B,MIR142,CNOT6L,MIR9-1,AGO1,MIR135B,PDE12,MIR191,MIR145,MIR1-1,TNRC6C,ROCK1,HNRNPD,MIR885,MOV10,MIR190B,MIR26B,YTHDF1,CNOT8,MIR340,MIR495,POLR2G,MIR211,MIR23A,MIR140,EXOSC8,GTPBP1,PRR5L,MIR130B,MIR98 |
| 1.675e-04 | -8.69 | PUS1 (pseudouridine synthase 1) | protein interactions | 80324 | 130 | 56 | 19454 | 5460 |
NDUFS6,PDHA1,GADD45A,HSPD1,PPP1R12A,COX8A,MRPS11,PCNA,SCPEP1,ATP5F1D,FARSA,PFDN1,PFDN5,NDUFV2,WDR12,PEX3,ZNF664,SSBP1,GATD3,FAHD1,YBEY,RHOH,CEP19,RMND1,MALSU1,MRPL12,CDC42,ACAA2,P3H1,QRSL1,MTRES1,AMACR,EXD2,THUMPD1,PPM1G,RPA3,ARPC2,HSCB,WDR3,MRM2,AUH,MTG2,MYC,EMILIN1,TUFM,PCCB,FBXW11,UBE2H,PFDN4,NRP1,CCNF,TRMT6,GTF2F1,ETNK2,RHOJ,IDE |
| 1.675e-04 | -8.69 | soft_tissue-fat-liposarcoma-pleomorphic | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-pleomorphic | 16 | 12 | 16828 | 4835 |
PTEN,TERT,PIK3CA,FBXW7,KIT,RB1,CTNNB1,TP53,EWSR1,IDH1,HRAS,KRAS |
| 1.675e-04 | -8.69 | FNIP1 (folliculin interacting protein 1) | protein interactions | 96459 | 34 | 20 | 19454 | 5460 |
FLCN,GSK3A,HNRNPL,PTGES3,HSPA5,GABARAP,VTA1,CUL2,CDK4,CUL3,RRAGA,PRKAB1,FEM1B,CFTR,YWHAG,COPS5,YWHAH,PRKAG1,FBXW11,HSP90AA1 |
| 1.675e-04 | -8.69 | CDC42BPG (CDC42 binding protein kinase gamma) | protein interactions | 55561 | 34 | 20 | 19454 | 5460 |
YWHAZ,SMAD4,POU1F1,KXD1,TBK1,UBXN6,ATG16L1,AR,YWHAH,CDC42,DYNLL1,HNRNPL,ESR2,HSPA5,TRMT61A,RPL28,EEF1AKMT3,LURAP1,CRYBB3,HSPA8 |
| 1.675e-04 | -8.69 | FAM86C1P (family with sequence similarity 86 member C1, pseudogene) | protein interactions | 55199 | 34 | 20 | 19454 | 5460 |
DOK6,CTTNBP2,EEF2KMT,MAGED4B,CDR2L,SAT1,CSNK2B,GPSM3,HNRNPF,NT5C3A,ZBTB39,TRAF1,CDKN2D,SFN,YWHAG,YWHAH,SPG21,YWHAZ,SEPHS2,YWHAB |
| 1.675e-04 | -8.69 | CCDC74A (coiled-coil domain containing 74A) | protein interactions | 90557 | 34 | 20 | 19454 | 5460 |
ZNF655,UBE3A,PSMC5,SH2D1A,THNSL1,PSMB4,CEP19,PSMC1,PSMD12,PSMD6,ADRM1,KDM1A,PSMD4,PSMD1,PSMC4,PSMD3,PSMC3,PSMD7,PSMD14,PSMD10 |
| 1.675e-04 | -8.69 | CCL11 (C-C motif chemokine ligand 11) | protein interactions | 6356 | 34 | 20 | 19454 | 5460 |
CCR5,CXCL3,CXCL14,CCL27,CCR2,CXCL11,CXCL9,CCL2,CCR3,CXCL10,CCL8,DPP4,XCL1,CXCL12,CXCL1,CCL5,CCL11,CCL28,NUDT3,CCL18 |
| 1.677e-04 | -8.69 | RNF10 (ring finger protein 10) | protein interactions | 9921 | 80 | 38 | 19454 | 5460 |
UBE2E2,TLE1,RSPH1,MOV10,OST4,YWHAH,XPO1,UBE2E3,UBE2D1,DDX23,DCAF5,UBE2H,HSP90AA1,ENO1,CCDC90B,TBCCD1,UBE2I,RPS20,PRNP,VIRMA,BTG3,APEX1,MDM2,LRIF1,UBTD1,EGLN3,UBE2W,TULP3,UBE2V1,EEF1A1,HAUS2,BCL7B,RPS24,HSPA8,TRIM63,TRIM26,UBE2D3,KDM1A |
| 1.677e-04 | -8.69 | CDV3 (CDV3 homolog) | protein interactions | 55573 | 80 | 38 | 19454 | 5460 |
FIS1,ILK,BICD2,ZFAND6,NAA50,SUGP1,NDUFAF2,RAB11A,CHMP2A,PRNP,GRPEL2,MRPS28,RFX5,RPS20,CCNF,RAB31,MIDEAS,GLIPR2,LEMD3,MOB3C,GNAI3,LMNA,RPA2,LARP4B,UBL4A,NDUFA2,UQCC3,STX7,STAU1,NSFL1C,HSPA8,EWSR1,NUP50,RPA3,BAP1,PPP1R12A,PML,RBM3 |
| 1.677e-04 | -8.69 | FAM133A (family with sequence similarity 133 member A) | protein interactions | 286499 | 80 | 38 | 19454 | 5460 |
TRAF2,THAP1,EIF3J,RAF1,NAA35,HSDL2,TP53,PRR13,PRKCA,HECTD1,MACROH2A2,CASK,ATP5IF1,UBE3A,IMPACT,NKAPD1,SPECC1L,PRCP,PPIL4,CSNK2A1,ACTR3B,CEP70,NT5C2,FAM133B,DHPS,STAC3,LANCL2,BRCA1,TRIM23,NOS1AP,CSNK2B,RBMX2,MACROH2A1,FOLR1,CMTR1,DBT,KCTD9,KCTD10 |
| 1.682e-04 | -8.69 | Global Genome Nucleotide Excision Repair (GG-NER) | REACTOME pathways | R-HSA-5696399 | 85 | 43 | 10285 | 3229 |
RFC2,ACTL6A,POLD4,ACTB,SUMO2,CCNH,COPS7B,POLD2,RPA2,PIAS1,CDK7,MNAT1,CETN2,POLE3,INO80E,GTF2H2,UBA52,PARP2,UBB,COPS2,COPS5,RUVBL1,POLE4,ERCC3,UBE2N,UBE2V2,LIG3,GTF2H4,SUMO1,INO80C,COPS7A,RPA3,SUMO3,RFC5,UBE2I,RFC3,PCNA,RAD23B,RPS27A,GTF2H5,COPS4,RFC4,TFPT |
| 1.683e-04 | -8.69 | DET1 (DET1 partner of COP1 E3 ubiquitin ligase) | protein interactions | 55070 | 153 | 64 | 19454 | 5460 |
RBMS2,ATG16L1,RPL27A,MYL6,ACACA,HSP90B1,TXNL1,HSPA8,CRY1,FOS,CSTB,UNC45A,AZGP1,ST13,PCCB,COPS7A,HSP90AA1,COP1,TRIB1,H1-1,CCT2,ELMO2,UBE2E3,STUB1,PPP5C,JUNB,MAD2L2,TXN,TXNDC12,SOX2,NUDCD3,JUN,CCT5,CYB5B,CSTPP1,MSRB3,CAPZA2,SIX5,DNAJB4,PDIA6,PC,HSD17B10,ARGLU1,COPS4,FN3KRP,TTC4,COPS5,GAPDH,RNF14,PDIA3,UBE2E2,DNAJC7,RPL23,FOSL2,FKBP4,TYMS,COPS2,AIP,MDM2,GLRX,CACYBP,HSP90AB1,DCUN1D1,COPS7B |
| 1.689e-04 | -8.69 | YY1 (YY1 transcription factor) | protein interactions | 7528 | 427 | 154 | 19454 | 5460 |
XRCC5,DDX5,PCGF2,EP300,YAF2,HDAC5,FOXP2,COIL,ACTL6A,ADNP,FKBP1A,NUFIP2,MFAP1,VPS72,ELK3,NIPA2,CPSF1,TACO1,ZHX3,PHF12,ZMYM2,SF3B4,SNRNP40,APEX1,LRIF1,CUL3,CREBBP,HNF1B,MYC,RBM15B,KANSL3,BRCA1,FAS,RCL1,SP1,BAX,MORC2,BAG2,DNAJB4,RUVBL2,SLC39A7,INO80C,FAM76B,SEMA4C,RUVBL1,ZNF592,PCGF6,RAD21,MSL2,FOXP4,PAX6,GTF3C3,MRPS17,MAX,RAF1,SAP30,ELF1,SOX2,EZH2,CRKL,ZRANB2,MTA2,EED,WDR82,ZHX1,IL10,LYAR,FAM98A,EGLN3,PPIA,INO80E,MDFI,LHX2,HCFC2,BAP1,RPA3,USP8,HMGB1,FBXW7,SGF29,HDAC3,GTF2I,HSPA5,CXXC1,BCL6,KLF12,TOX4,RPA2,HEXIM1,CTTN,EZH1,ZNF330,CREB1,PSPC1,TRIM24,INTS12,GABPA,NR1H2,JUNB,BCCIP,PPP1R10,UBB,ZNF687,AAMDC,SMARCA5,H2BC9,TADA3,F9,MECP2,SMAD2,SNIP1,TFPT,RPL23A,RING1,SEM1,H3C1,H2BC14,MDC1,MEPCE,TP53,RPSA,ZNHIT1,ZMYM4,SMAD1,ZMYM3,NFE2L2,GABPB1,TFCP2,CBX3,DMAP1,DDX42,TAF2,SPRY1,RCHY1,SSBP1,SMAD3,RB1,GATAD1,BRMS1L,TOP1,PLEKHF2,CAND1,RPL35A,KLF9,CDK9,MDM2,ZNF24,NFKB1,PPIL4,SMCHD1,SMAD4,FOXP1,TESK1,TAF9 |
| 1.689e-04 | -8.69 | regulation of interleukin-12 production | biological process | GO:0032655 | 64 | 33 | 18204 | 5365 |
TLR4,CD40LG,LEP,AGER,MIR21,CCL19,CCR7,TLR8,LILRB1,CD40,HSPD1,TLR2,IRF1,TRAF6,PLCB1,TLR9,SYK,HMGB1,NFKB1,IRF8,CLEC7A,CD36,IL23A,LTB,IL10,IL12B,IFNG,TIRAP,IDO1,TLR3,ACP5,CD47,FOXP1 |
| 1.689e-04 | -8.69 | proton motive force-driven ATP synthesis | biological process | GO:0015986 | 64 | 33 | 18204 | 5365 |
NDUFB4,STOML2,ATP6V1A,ATP5PB,NDUFS2,ATP5MG,NDUFB6,ATP5MC1,ATP5F1D,NDUFB5,ATP5F1B,NDUFV2,ATP5F1E,NDUFS3,ATP5PD,NDUFA1,NDUFS8,NDUFAB1,ATP5F1A,NDUFB10,SDHC,NDUFS6,ATP5PF,NDUFC2,SDHB,ATP5MK,ATP5PO,NDUFA12,ATP5MC3,NDUFA5,NDUFB7,NDUFA2,NDUFB8 |
| 1.690e-04 | -8.69 | CLEC4D (C-type lectin domain family 4 member D) | protein interactions | 338339 | 260 | 100 | 19454 | 5460 |
CDK5RAP3,TMEM30A,CLPX,DDRGK1,ASIC1,SPTAN1,RAB1B,LANCL1,MPDU1,DNM2,SPINT2,XPO5,PDHA1,RPN1,PLD3,HGS,STBD1,ERLIN2,TMEM59,PCDH19,ACTN4,VDAC1,EMC8,SSRP1,POLDIP3,RAB18,NDUFA4,TMEM87A,MYO1B,MYO6,CUL2,RAB11A,FMC1,VEZT,BTF3,LRRC8A,GNB1,ATP6AP2,CLIC4,CYB5R3,VDAC2,GNG12,PGRMC1,EFHD1,RAB6A,YTHDF1,EMC1,FXR2,XRCC5,ATPAF2,DDX39B,JAGN1,HADHA,ESYT1,POR,OSBPL8,TMOD2,DHRS7,KARS1,CALR,TMEM199,GLO1,ANKRD46,ARF6,DKC1,PTPN1,SRPRA,SEC23A,ACTR2,ARPC3,CAPZA2,TFRC,GNAI3,TP53,YTHDF2,MRPL11,CCDC47,PREB,PTGES3,SLC25A11,EMC2,CALU,TUFM,RACGAP1,GORASP2,TMOD3,CTNNA1,LIG3,PELP1,EPCAM,RPA2,MET,SEC22B,NTPCR,CNP,AIF1L,ITM2B,BANF1,DLAT,ARPC2 |
| 1.690e-04 | -8.69 | presynaptic membrane | cellular component | GO:0042734 | 168 | 71 | 19108 | 5553 |
PSEN2,AP2M1,PSENEN,ADORA1,SLC6A11,SLC1A2,SLC6A2,NCSTN,NLGN2,CPLX3,KCNJ11,PPFIA2,SLC6A4,CHRM1,ADORA3,APH1A,EFNB1,STXBP1,SLC4A8,GRIA1,SLC6A3,SNAP25,HTR2A,CHRNB2,FXYD6,GAD2,LPAR1,SLC6A1,KCNJ3,STX11,RIMS4,ZDHHC17,FCHO2,CTNNB1,GRM2,EXOC3,GRIK1,GPM6A,EPHA4,SNAP91,KCNJ8,ATP2B4,STX1A,PDE2A,RGS7BP,RIMS3,PCDH17,P2RY4,OPRK1,LRRC4B,NPTN,KCNA2,LRFN3,KCTD12,NTNG2,CNR1,KCNH1,GABBR1,DRD1,P2RY1,SYP,CNTN1,KCTD16,PSEN1,CASK,PICK1,KCNA3,LPAR2,IGSF21,PICALM,KCNC1 |
| 1.692e-04 | -8.68 | LYRM4 (LYR motif containing 4) | protein interactions | 57128 | 72 | 35 | 19454 | 5460 |
MTRES1,GPX7,CARTPT,NDUFAB1,ISCU,METTL15,MRPL11,DDAH1,CDNF,FASTKD5,CHCHD2,HSCB,KRAS,FBXW7,HINT2,HAPSTR1,RNF113A,GFM1,HSPD1,EXD2,MRPS26,FXN,RIT1,RHOG,TUFM,KLHL22,MTRF1,AUH,EPS8,PMPCA,IDE,GATD3,TACO1,SSBP1,NECTIN2 |
| 1.692e-04 | -8.68 | CHMP4A (charged multivesicular body protein 4A) | protein interactions | 29082 | 72 | 35 | 19454 | 5460 |
IDH1,HSPE1,RBBP7,SLC25A32,TFG,VTA1,CHMP2B,RANBP1,SOX2,CHMP4C,CHMP1A,ADSS2,VPS4B,RDH12,SMARCB1,STAMBP,SELENOF,EFHD2,CDCA3,DCK,CHMP5,ABHD17A,CHMP2A,ZBTB2,PPIA,NFYA,ARL6IP6,BTF3,NTAQ1,FCGR2A,CHRAC1,FYTTD1,USP15,VPS4A,HOXC4 |
| 1.692e-04 | -8.68 | ANAPC13 (anaphase promoting complex subunit 13) | protein interactions | 25847 | 72 | 35 | 19454 | 5460 |
MYC,MOV10,CDC16,NAA50,CDC26,ANAPC15,COPS5,CENPW,ANAPC4,CDC23,CDK12,DICER1,PELO,COPS2,ANAPC2,FZR1,TUBB,UBA3,CENPM,PAFAH1B1,CDC42,PPP2R1A,ANAPC13,SKA3,SMNDC1,ZNF574,SDHC,TCOF1,CPNE2,ANAPC16,TRA2B,RPL28,SAP18,RIGI,COPS4 |
| 1.692e-04 | -8.68 | FBXO25 (F-box protein 25) | protein interactions | 26260 | 197 | 79 | 19454 | 5460 |
RUVBL2,MYO1B,RPAP3,PPP1R12A,CCT8,RPS27A,MSH6,HNRNPF,ATP1A2,G3BP1,RUVBL1,CSE1L,EEF2,CCT5,PSMC3,DDX42,TUBB4B,RPN1,PPID,IGBP1,HP1BP3,KRT8,RPL12,GTF2B,EIF4E2,FBXO32,ELK1,CDK9,CCT7,CAND1,RPS10,TTC9C,TCP1,XPO1,PSMD3,DNAJB2,HAX1,DNAJC7,IL21,HSPA8,TRUB1,HMCES,SPECC1L,PSMC1,UNC45A,MARS1,HSPA5,SKP1,PRRG1,UBE2D3,PPP1R8,MYL12B,ARHGAP1,PRKCA,BORCS5,PRMT5,PSMC5,ALB,WDSUB1,ENO1,TMA7,MAT2B,ATP5F1B,PSMD4,TMOD3,ACTB,PSMD6,ATP5F1A,SAMHD1,CFL1,DNAJC8,MCM3,HSP90AA1,ATP1A1,XPOT,PNPO,PIP4K2C,UBE2E3,MYO6 |
| 1.692e-04 | -8.68 | SPG21 (SPG21 abhydrolase domain containing, maspardin) | protein interactions | 51324 | 197 | 79 | 19454 | 5460 |
S100B,PCNA,GAD2,KRAS,RRAGB,SATB1,DCTPP1,LEPROTL1,PRPS1,TFG,PAX6,ZNF263,TPD52,PNMA5,ZNF581,DDX39A,APOO,TRAF2,ZMYM3,SPG21,ACOT13,GNAZ,SYNGR3,SPRED2,PSMB4,XXYLT1,CD4,SPMIP5,VAMP7,CIDEB,MOV10,PFDN5,TMEM208,SSBP4,GAS8,NAB2,CLDN22,ATPAF2,RABAC1,RAB9A,RTN4,NME4,EIF1B,CMTM6,GRPEL1,SPTBN1,AGTRAP,PLP2,NRDE2,BORCS6,SPMIP6,RPRD1B,LMNA,TFIP11,ZBTB42,SLC35E3,STUB1,UFSP1,VMAC,SYNGR1,GSK3A,TXN,EIF4H,KCTD9,TRIM54,MYG1,SRC,TRAF1,NDUFAF2,SPRED1,FBXO44,HMGCS1,LAMTOR1,NIF3L1,SYP,TRIM23,CCHCR1,REEP6,ARMC7 |
| 1.713e-04 | -8.67 | Deubiquitination | REACTOME pathways | R-HSA-5688426 | 301 | 124 | 10285 | 3229 |
TFPT,CCNA2,H2BC9,RAD23B,H2BC1,TOMM20,H2AC14,HGS,TNKS2,PSMB9,WDR20,RNF128,PSMD6,TRAF6,UBE2D1,PSME2,BIRC2,INO80C,SMAD1,PTRH2,VDAC1,NEDD8,PSMD12,TNFAIP3,CFTR,USP16,USP2,MYC,RUVBL1,JOSD1,TADA3,H2AC7,UBB,MBD5,SIAH2,PSMD14,PSMD7,H2BC12,FKBP8,IFIH1,PSME1,USP15,USP8,H2BC11,VDAC2,TNKS,PSMA2,PSMB6,PSMC5,PSMB11,PSMB10,POLB,H2BC17,SMAD2,PSMA4,PSMC4,PSMA3,PSMB5,ADRB2,CDC20,BAP1,ACTL6A,PSMB1,PSMD3,PSMB7,PSMD4,AR,RNF146,RPS27A,TRAF2,PSMA1,H2AC6,TP53,PSMC3,USP3,H2AC4,UFD1,RIGI,SEM1,BRCA1,USP5,PSMB4,NLRP3,PSMA6,PSMD1,PSMB2,MUL1,BECN1,ADRM1,H2AC13,STAMBPL1,PSMC1,SNX3,SMAD4,BABAM1,USP13,USP30,TGFBR2,MAVS,UBA52,SMAD3,TAF10,INO80E,EP300,IDE,NFKBIA,OTUD7B,PSMD10,PSMB3,H2AC25,H2BC14,PSMA5,PTEN,TOMM70,MAT2B,USP14,UCHL3,SENP8,STAMBP,MDM2,H2AC1,ACTB,TAB1,RCE1 |
| 1.714e-04 | -8.67 | TRAF6 mediated induction of TAK1 complex | REACTOME pathways | R-HSA-937072 | 17 | 13 | 10285 | 3229 |
TICAM1,LY96,SARM1,RPS27A,UBA52,TLR4,UBB,TAB2,TICAM2,TLR3,TRAF6,CD14,TAB1 |
| 1.718e-04 | -8.67 | axon ensheathment | biological process | GO:0008366 | 130 | 58 | 18204 | 5365 |
DAG1,AKT1,LARGE1,MIOS,SLC25A46,KLK6,MTMR2,GAL3ST1,ORMDL3,CLU,AKT2,MARVELD1,GPC1,PMP22,HRAS,CXCR4,TPPP,MOBP,NAB2,ASPA,FIG4,KCNJ10,RAF1,LPAR1,GPM6B,GALC,MPZ,DEGS1,FA2H,GNPAT,HYCC1,CNTNAP1,ID4,NKX6-2,HEXA,CNTN1,AMIGO1,TLR2,ZNF24,ORMDL1,EGR2,EIF2B5,B4GALT6,CD9,SOD1,DICER1,NTRK2,MYRF,PTEN,CLDN11,HEXB,PLP1,EIF2B2,MAP2K1,NCSTN,NAB1,ACER3,ILK |
| 1.718e-04 | -8.67 | ensheathment of neurons | biological process | GO:0007272 | 130 | 58 | 18204 | 5365 |
CLDN11,PTEN,MYRF,ILK,ACER3,NAB1,MAP2K1,NCSTN,EIF2B2,PLP1,HEXB,ORMDL1,TLR2,ZNF24,AMIGO1,CNTN1,NTRK2,DICER1,SOD1,CD9,B4GALT6,EIF2B5,EGR2,GPM6B,LPAR1,GALC,RAF1,KCNJ10,ASPA,FIG4,NAB2,HEXA,NKX6-2,ID4,HYCC1,CNTNAP1,GNPAT,DEGS1,FA2H,MPZ,MARVELD1,AKT2,CLU,ORMDL3,MTMR2,GAL3ST1,KLK6,MIOS,SLC25A46,LARGE1,AKT1,DAG1,MOBP,TPPP,CXCR4,HRAS,PMP22,GPC1 |
| 1.721e-04 | -8.67 | MAK16 (MAK16 homolog) | protein interactions | 84549 | 156 | 65 | 19454 | 5460 |
RPL31,RPS24,RPL3,HAPSTR1,HMGN4,KRAS,RPL17,RIGI,PAK6,SRSF4,RPS27A,RPL28,RPSA,RAF1,RBM34,NUPR1,RPL32,SRSF1,KRR1,RPL8,SRP14,HP1BP3,LYAR,SURF6,DKC1,MDM2,IFI16,CSNK2A1,ZCCHC9,TSNAX,NOL12,SIRT7,HNRNPH2,STAU1,RPL4,NOP53,NPM3,DGCR8,RPS15,UTP23,BRIX1,MACROH2A2,RPL26L1,RPLP0,PRKRA,FGFBP1,RPL13A,RPL35,RPF1,SNRNP40,SRPK2,RPL19,RSL24D1,LIN7B,RPL7A,CIAO1,RPF2,MYC,ZNF668,FTSJ3,ZCRB1,ATG3,RIT1,NSA2,H1-1 |
| 1.721e-04 | -8.67 | ABCF2 (ATP binding cassette subfamily F member 2) | protein interactions | 10061 | 156 | 65 | 19454 | 5460 |
RPS16,FZR1,CDC5L,ZBTB2,DKC1,CDK9,PHB1,RCHY1,RPL6,WWP2,MOV10,CTNNB1,DDRGK1,COPS5,GNL1,AHCYL1,HNRNPA2B1,MAP1B,IGF1R,EZH2,SKA3,TP53,RAF1,KBTBD4,EEF1A1,FAF2,ISG15,ESR2,RPL10,VIRMA,DYRK1A,MAD2L1,PPP1R10,PPP5C,CCNF,PHF12,PSPC1,LMBR1L,PTEN,BRCA1,THTPA,ILK,CUL3,TM9SF4,MYC,BTF3,FBXO7,FBXW7,STAU1,UFL1,HSCB,EIF5B,HSPA5,ZC3H15,RPA3,RNF113A,EP300,HADHA,PRKCB,GRM2,METTL14,FGFR1,RPA2,PIH1D1,ATG16L1 |
| 1.721e-04 | -8.67 | ETFB (electron transfer flavoprotein subunit beta) | protein interactions | 2109 | 156 | 65 | 19454 | 5460 |
RPA2,METTL14,HEXIM1,IRF2BPL,MTRES1,NDUFAB1,HSCB,STAU1,RER1,ADRB2,CRYZ,SOD1,RPA3,NGRN,EXD2,GPX4,GFM1,RHOB,BRCA1,DNAJC19,DSN1,MTG2,AUH,PMPCA,PRKACB,TUFM,CAPG,ATP6AP2,TACO1,CCDC90B,DLST,PITPNB,GLTP,PDHA1,GFM2,RAF1,MRPL11,AURKAIP1,HADH,METTL15,ETFA,MEPCE,FASTKD5,HSPD1,TMT1A,SFXN1,HINT2,AK2,RHOG,TMEM70,DNAJC7,MRPS26,GRSF1,MTRF1,XPO1,ETFRF1,PPIA,COX14,RMND1,CAV1,SSBP1,AIFM1,COX4I1,DSTN,GATD3 |
| 1.733e-04 | -8.66 | DSG2 (desmoglein 2) | protein interactions | 1829 | 242 | 94 | 19454 | 5460 |
RAB11A,SFN,MYC,OST4,CDKL2,NTRK3,YWHAZ,RHOB,LAMTOR1,SEC61B,DLST,LMBR1L,ESR2,SEC62,RND2,BET1,CLDN4,RAB5A,PMAIP1,HSPA8,STX7,ADRB2,GPC1,CTNNB1,YWHAG,YWHAH,RAB5C,LAMP2,ATG9A,YWHAB,RHOG,SOSTDC1,EED,GJA1,RAB35,EGLN3,DIRAS3,RHOH,ISG15,RAF1,MOB3C,SART3,RND3,PDHA1,PTRH2,RAB4A,RPN1,TMT1A,ZYX,FLOT1,UBE2A,EPHA4,KRAS,CHCHD2,AR,DNAJC5,USP14,RAB2A,NRP1,CTNNA1,CCNF,VAMP3,VIRMA,RHOJ,ST7,CDC42,ARL15,FGFR1,PAK5,JUP,RPA2,RAB9A,DERL1,RHOU,RPA3,PIAS1,HDAC6,LAMP3,STYK1,RAC2,HSD17B11,HRAS,CAV1,STX6,LMAN1,PRNP,ARF6,DNAJC1,TP53,NUPR1,ACTR2,TFCP2,ABCE1,RAB3B |
| 1.733e-04 | -8.66 | ACSL3 (acyl-CoA synthetase long chain family member 3) | protein interactions | 2181 | 242 | 94 | 19454 | 5460 |
SYVN1,DERL1,RAB9A,SQSTM1,RPA3,SIRT7,RPA2,LMNA,SSR1,CDC42,ST7,CFTR,SEC63,GNAI2,VIRMA,COPE,YES1,SLC1A1,CCNF,UBE2H,AR,RAB2A,CIAO1,FKBP8,ADIPOQ,RAB3B,IGF1R,EMC2,FURIN,DDX42,CCDC47,FBP1,TMPO,LMAN1,ARF6,DNAJC1,HSD17B11,TES,RAC2,ACSL4,COQ8A,PTPN1,ESYT1,LAMP3,DPP4,SLC25A46,STX7,PXMP2,UCHL3,UFL1,EMC1,STAU1,HSPA8,RAB5A,EP300,TMEM106B,TSPAN15,SEC62,RND2,OTULINL,MAD2L2,ESR2,RMDN3,SEC61B,LMBR1L,NTRK3,RIT1,FAS,LMNB1,MYC,RAB11A,CUL3,PAEP,KRAS,WDR19,SKA1,CYP2C9,TMT1A,RND3,RPN1,STIM1,PTRH2,RAB4A,DNAJC25,SOX2,B3GNT2,EGLN3,GJA1,RAB35,RHOG,ATG7,MAPK4,LAMP2,RAB5C |
| 1.734e-04 | -8.66 | PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4) | protein interactions | 30849 | 102 | 46 | 19454 | 5460 |
TUBB,FBXO22,ESR2,VIRMA,APLNR,ATG3,LAMTOR1,CCT2,MAPRE1,PFDN4,PFDN2,GPR17,PSMA4,MYC,EEF1G,STAU1,NRBF2,DVL2,RPA3,RAB9A,RAB5A,NUBP2,HECTD1,PARD6A,RPL7,TCP1,CCT7,EGLN3,GJA1,BECN1,SLC2A1,STYK1,YWHAB,PFDN5,LAMP2,MOV10,XPO1,ATG7,YWHAG,YWHAH,KRAS,PFDN1,CCT8,KRIT1,CCT5,MGARP |
| 1.734e-04 | -8.66 | IRF2 (interferon regulatory factor 2) | protein interactions | 3660 | 102 | 46 | 19454 | 5460 |
ATG7,CSNK2A1,NFKB1,DPY30,PPP3CA,GATD3,RPLP1,COQ8A,SSBP1,HDHD5,TMPO,MDM2,PSMC3,NUDT19,IRF8,NFE2L2,UBE3A,RFC2,G3BP1,TRIM63,IRF1,RPL39,TUFM,PYCR2,HSP90AA1,FAU,LIG3,ENO1,STAT1,IRF2BP1,LDHA,IDH3B,IRF2BPL,CDK1,LARP4B,IDH2,LSM12,MTDH,EP300,MAIP1,HIRA,RPA3,XRCC5,HCFC2,NDUFS2,HMGB1 |
| 1.735e-04 | -8.66 | UQCRC1 (ubiquinol-cytochrome c reductase core protein 1) | protein interactions | 7384 | 212 | 84 | 19454 | 5460 |
MOV10,LAMTOR2,EMC4,NDUFV2,CTNNB1,POR,SLC25A28,AGR2,HNRNPD,NDUFB8,COQ8A,AIFM1,PHB1,COX4I1,COMT,CORO1C,ATP6V1A,RAC2,HNRNPL,PRNP,LMAN1,NDUFS8,MYL12A,UQCRH,EGLN3,ZBTB2,UBL4A,MTCH2,MAP1LC3B,CYB5R1,EEF2,NDUFS6,NDUFS3,PDHA1,NDUFA12,SFXN1,RUVBL2,EMC2,EMC8,KRAS,VDAC1,TRIM63,SRPRB,PSMB10,TOMM6,FKBP8,RIGI,MYC,PMPCA,ATP5F1A,HMOX2,PCCB,ATP1A1,RIT1,VDAC2,CCNF,UQCRC2,CYB5R3,SMU1,ATP5F1B,MGST3,ACTB,SLC25A4,UQCRQ,ESR2,VIRMA,TOMM22,CFTR,BORCS6,ARMCX3,STOM,HSP90B1,NDUFA5,CYC1,RPA3,SIRT7,HADHA,RTN4,NDUFS2,EMC1,PDHB,STAU1,PHB2,PIAS1 |
| 1.736e-04 | -8.66 | POLE (DNA polymerase epsilon, catalytic subunit) | protein interactions | 5426 | 133 | 57 | 19454 | 5460 |
EGLN3,POLE3,MDM2,TOP1,TTC9C,EEF1AKMT3,PHB1,TOPBP1,DNAJC7,HAX1,HSPB8,UBXN6,PTGES3,MSH6,SSRP1,POLE4,RPL28,KRAS,BAG2,PCNA,PABPC1,DTWD2,GINS4,VPS33A,EZH2,TOP3B,VIRMA,POLR2B,PSMD4,CIB2,ZNF330,LMBR1L,CCNF,RIT1,BMERB1,POLD4,FBXW11,BRCA1,CIAO1,CUL3,MYC,POLA2,DUSP26,STAU1,HSPA8,XRCC5,TIMP3,POLD2,SIRT7,RPA3,PRIM2,MED23,RPA2,CDK1,CCNA2,CFTR,RFXANK |
| 1.736e-04 | -8.66 | PPA2 (inorganic pyrophosphatase 2) | protein interactions | 27068 | 133 | 57 | 19454 | 5460 |
TAX1BP1,TXNDC12,ENO1,CCNF,SERPINH1,UBE2H,PCCB,TUFM,BAG3,AUH,MTG2,MYC,CTSD,SRI,GFM1,EXD2,RPA3,ARCN1,MTRES1,GSTP1,FKBP14,CD2AP,PRNP,GATD3,COMT,AIP,SSBP1,PPP1R11,HNRNPD,AGR2,RHOG,MTRF1,GRSF1,IMMP2L,SAR1B,MPST,FASTKD5,MEPCE,TRIM63,NEDD8,CHCHD2,UFM1,HINT1,SCPEP1,HINT2,TCOF1,HNRNPA2B1,HSPD1,RAB1A,SLC25A24,SOD2,PDHA1,TIMM8A,GLRX5,MECR,H1-3,TOP3B |
| 1.742e-04 | -8.66 | positive regulation of connective tissue replacement | biological process | GO:1905205 | 12 | 10 | 18204 | 5365 |
ROCK2,MIR34C,MIR34A,MIR16-1,MIR214,MIR17,PPP3CA,ROCK1,MIR34B,MIR195 |
| 1.744e-04 | -8.65 | CCNB1 (cyclin B1) | protein interactions | 891 | 233 | 91 | 19454 | 5460 |
RMDN3,LMBR1L,GADD45G,JPT1,OTUD7B,GRB10,H1-1,RIT1,SP1,BRCA1,GADD45B,RHOB,EP300,SKP1,STAU1,UCHL3,CDKN1A,PRDX3,PPP1CB,H1-5,CKS2,SDHAF2,XPO1,DPY30,MARCHF5,NDC80,PRDX1,CDKN1B,MGMT,PCNA,CDK5,GADD45A,RNASEH2C,MEF2C,CCAR1,TRIM37,KRAS,ERLIN2,TULP3,CKS1B,NGB,EZH2,CSNK2B,PSMA6,RPS3,DCLRE1C,CCNF,VIRMA,CDC20,RHOBTB3,USP14,PPP1CC,CDC16,ANAPC4,AP2A1,SQSTM1,SIRT7,DVL2,RPA3,STK38,UBE2K,CCNA2,CDK7,CCNH,UBA52,RPS14,AKR7A2,TRIM36,FGFR1,BTG2,STOM,RPA2,CDK1,RB1,UBE2N,CDC5L,MIF,TOP1,FZR1,CAND1,GAPDH,MFN1,PLEKHO1,MAP4,MNAT1,TGFBR2,ANAPC11,IKZF5,MAP1LC3B,C1QC,MAD2L1BP |
| 1.745e-04 | -8.65 | TMX2 (thioredoxin related transmembrane protein 2) | protein interactions | 51075 | 221 | 87 | 19454 | 5460 |
YIF1A,NSDHL,RUSF1,SFXN1,TMEM50B,NSG1,SRPRB,CCL2,AGPAT5,NRM,CCDC47,COMMD8,SELENOK,INSIG2,TMEM31,HSD17B11,COX20,FA2H,HSD11B1,IER3,FUNDC2,AIG1,CD81,TMBIM6,LRAT,BTN2A2,SLC35A1,TMEM254,DERL1,TMX2,RPA3,PLP2,HACD2,TRAM1L1,RPA2,CYBC1,VAMP3,CDIPT,MGST3,HMOX2,GJB2,VAMP5,MARCHF3,MFSD14B,SPOP,MLN,LEPROTL1,SACM1L,PAEP,TMEM176A,SLC4A8,STX12,TMEM14B,CTSA,CYB5A,KCNA2,TMEM97,FAM241A,TMEM208,C2CD2L,FAM241B,SCAMP5,RABAC1,TMEM203,EMP3,STX7,CCDC167,OTULINL,VAMP1,CTXN3,GINM1,BET1,CMTM7,FDFT1,FAM3C,SMCO4,VAPB,TMEM115,TLR5,FAM177A1,THBD,TVP23B,REEP4,TM9SF4,FAXDC2,ATP1A3,CGRRF1 |
| 1.746e-04 | -8.65 | CD44 (CD44 molecule (IN blood group)) | protein interactions | 960 | 230 | 90 | 19454 | 5460 |
RHOH,SNX18,RHOG,ATG9A,GTF3C3,KRAS,MMP9,MADCAM1,RND3,MOB3C,EZH2,RAB4A,MSX2,TNPO2,RAF1,APEX1,LGALS3,DYNLL1,PARP2,CYB5R3,SLC7A11,RHOB,TOMM40,HBEGF,SLC16A4,SRGN,MYC,RAB11A,RNF11,STAU1,GPC1,HSPA8,HADHA,EMP3,EP300,TMEM160,VAV2,EHD1,RND2,CDC5L,CAV1,ARF6,GRM1,RAC2,CDK6,CD4,HRAS,OSBPL8,SPP1,POR,TIAM1,CDC40,CAMKV,TGFBR2,ABCE1,SLC16A1,NUPR1,MAP2K3,CDK4,TCAF2,MTCH2,SRC,VIRMA,RHOJ,MSN,CTNNA1,ENO1,CDC73,STK11,EPHA2,COL1A2,LGALS8,CSK,NAA50,AKT1,AKT3,HSPA5,NF2,RBM22,HMGB1,SQSTM1,SNX33,SLC39A9,RHOU,MET,LEMD3,FGFR1,KDELR2,CDC42,IGFBP3 |
| 1.746e-04 | -8.65 | cytoplasmic vesicle lumen | cellular component | GO:0060205 | 326 | 125 | 19108 | 5553 |
SERPINI1,TMSB4X,TEX264,CLU,ACTN4,LYZ,TOLLIP,GHRL,GTPBP2,PSMB1,SRGN,GGH,CAB39,PYGB,FTL,DSN1,TUBB,PRDX6,ALB,NPC2,EEF1A1,CTSD,PSMA5,HMGB1,HP,TUBB4B,PSMB7,AGA,MIF,CAMP,OLA1,SCG3,FGR,JUP,FAF2,FAM3C,MAGED2,SERPINB1,IGF1,HEXB,DNASE1L1,PLAC8,VWF,RARRES2,CXCL1,PPIA,PSMD1,CTSA,S100A8,PSMA2,CCT8,ROCK1,PSMD3,TF,EEF2,RETN,NME2,CCT2,COTL1,SDCBP,XRCC5,VEGFA,FASLG,CAND1,HUWE1,CHI3L1,HSP90AB1,PSMC3,ACTR1B,COMMD9,TOR4A,PRDX4,PGAM1,PCYOX1L,FABP5,RAB27A,SLPI,ACTR2,PYCARD,B2M,GDI2,SERPINA3,PSMD14,PLG,DBH,PNP,PAFAH1B2,DNAJC3,SPTAN1,SRP14,PROS1,TIMP3,TGFB3,S100A11,HEBP2,PADI2,NEU1,TIMP1,GCA,CTSC,PSMD7,CYRIB,PSMD12,TTR,BACE1,SERPINA1,ILF2,CSNK2B,HSPA8,TGFB2,NFKB1,RNASET2,CDC37L1,CYB5R3,ARMC8,VEGFC,SELENOP,ATG7,GSTP1,CSTB,PSMD6,VTI1B,TRAPPC1,IDH1,HSP90AA1 |
| 1.749e-04 | -8.65 | CRCP (CGRP receptor component) | protein interactions | 27297 | 91 | 42 | 19454 | 5460 |
HAPSTR1,RPAP3,PDRG1,POLR1H,KRAS,DNAAF10,POLR1D,RPAP2,RBM12,TRMT1L,POLR2D,POLR2C,POLR2G,CSNK1G3,GNAZ,PIH1D1,RPRD1B,VAV2,POLR3B,POLR3H,POLR2F,RPRD1A,CYRIB,POLR2L,MGME1,LRIF1,POLR2B,SRC,BCCIP,POLR3F,POLR2I,POLR3GL,MOV10,MED4,PFDN2,H1-1,PFDN6,RIT1,POLR1B,MED21,AGR2,CHRAC1 |
| 1.749e-04 | -8.65 | ELK4 (ETS transcription factor ELK4) | protein interactions | 2005 | 91 | 42 | 19454 | 5460 |
ERH,ACAP2,ROCK1,ACTB,HNRNPL,SNRPD1,SNRPD2,PRMT5,CORO1C,DOK4,HSPB1,SERPINH1,ID1,IVNS1ABP,PPM1B,BRCA1,PRPF31,H2BC9,MRPL16,H2AC14,H2AC6,CAPZA1,PRPS1,H2BC14,GRPEL1,H2AC13,THRAP3,TRA2B,H3C1,AKAP12,SRSF7,H2BC12,PRPSAP1,FOS,SIRT7,H2AC25,LUC7L3,H2BC1,H2AC7,ELK4,H2AJ,WDR77 |
| 1.749e-04 | -8.65 | CEP78 (centrosomal protein 78) | protein interactions | 84131 | 91 | 42 | 19454 | 5460 |
UFL1,FBXW7,KCTD17,STAU1,PCGF6,FTL,SOD1,LTBR,DVL2,RPS28,HAPSTR1,EFNB1,SQSTM1,VPS33A,TMEM182,PNMA2,DYRK2,RAF1,ATG16L1,KBTBD4,ASPM,EIF2B5,SUMO2,SH3BP4,STT3A,EEF2KMT,LMBR1L,TMEM74,TRIM24,RC3H2,SNRNP70,HSPB1,MOV10,CREB3,CSK,PDIA3,CALR,XPO1,YWHAG,CTNNB1,DDRGK1,TPM3 |
| 1.757e-04 | -8.65 | EXOSC5 (exosome component 5) | protein interactions | 56915 | 159 | 66 | 19454 | 5460 |
XPO1,FGF1,DDRGK1,DIS3L,LSM3,MPHOSPH6,SNRNP70,PWP2,POLR2L,EIF4E2,PHB1,CDK9,PEG10,FZR1,LCA5L,RPS16,LSM5,TRIM62,SOX2,RPS7,EXOSC8,SH3GLB1,EXOSC3,HAPSTR1,PICK1,FHL3,OSTM1,MEPCE,KRAS,PSMA5,PSMA1,PSMA2,PSMA4,CUL3,HOXC4,EXOSC1,RBM7,UBE2H,ZNF655,PTEN,PSPC1,PSMA6,RPL19,ESR2,NMI,TRIM54,BORCS6,SF3A1,MYLIP,DDIT4L,TFIP11,SH3GLB2,UTP15,PALS2,RPA2,BIRC2,EXOSC4,TNFAIP1,PSMA3,C1D,RPA3,NKAPD1,WDR3,UFL1,MRPL41,STAU1 |
| 1.768e-04 | -8.64 | GST_C | interpro domains | IPR004046 | 22 | 15 | 18521 | 5414 |
HPGDS,GSTM3,GSTP1,EEF1G,GSTM2,GSTA1,GSTA4,GSTO1,GSTA2,GSTT1,MARS1,GSTM5,GSTM4,GSTT2B,EEF1E1 |
| 1.781e-04 | -8.63 | negative regulation of interleukin-10 production | biological process | GO:0032693 | 24 | 16 | 18204 | 5365 |
IL12B,MIR194-1,LILRB1,IDO1,CD274,MIR106A,FOXP3,TYROBP,VSIR,LILRB4,AGER,PDCD1LG2,FCGR2B,MIRLET7C,IL23A,MIR98 |
| 1.791e-04 | -8.63 | AGO1 (argonaute RISC component 1) | protein interactions | 26523 | 162 | 67 | 19454 | 5460 |
EIF4A3,SMAP2,STUB1,TRIM24,TAX1BP1,MATR3,VIRMA,ESR2,PRRC2A,PPP5C,CEP85,HNRNPC,CUL3,MYC,OTUD7B,PAIP2,IGF2BP1,HSP90AA1,DDX46,DDX5,HNRNPH2,YTHDF1,STAU1,FXR2,RBMS2,TRMT13,ZNF326,HEXIM1,FUBP3,SYNCRIP,WDCP,AIP,EIF2B2,PRNP,HNRNPL,CAND1,HSP90AB1,CNOT2,DDX50,MOV10,COPS5,CPEB1,GPRASP2,DICER1,HNRNPD,GARRE1,PABPC1,LSM14A,DHX9,ZC3H7A,RUVBL2,G3BP1,CNOT7,DCP2,HNRNPF,PTGES3,MEPCE,CNOT6L,YTHDF2,TNRC6C,TP53,IPO8,H2AX,DDX39A,SOX2,SART3,ILF2 |
| 1.791e-04 | -8.63 | TAB2 (TGF-beta activated kinase 1 (MAP3K7) binding protein 2) | protein interactions | 23118 | 162 | 67 | 19454 | 5460 |
BICD2,YWHAZ,HSP90AA1,HSPA14,EMILIN1,SFN,USP14,AR,TRIM29,MANSC1,TAB1,ESR2,EIF2AK2,TMEM74,TRIM27,UBE2I,BST2,CTDSP1,RPA2,NLRP6,UBE2M,ATG16L1,TANK,FBXO42,TIRAP,GTF2I,HDAC3,LITAF,MBD3,BAP1,TRIM5,HDAC5,AKAP1,ZFP64,TRIM22,SQSTM1,IKBKB,TRAF6,BECN1,USP15,NFKB1,EDEM1,YWHAH,XPO1,YWHAG,TPM3,ANKRD10,PRNP,CNTROB,EGLN3,SIN3A,TNIK,PPP2CB,TRIM45,SLC19A3,VPS33A,TLR3,TAB2,POLR2C,PPIL3,TRAF2,ISG15,TNF,ZBTB16,RBCK1,ZYX,BAG2 |
| 1.792e-04 | -8.63 | gliogenesis | biological process | GO:0042063 | 275 | 109 | 18204 | 5365 |
TSPO,NR2E1,RTN4,MYD88,EMX1,NTRK2,CD9,METTL14,B4GALT6,EIF2B5,PSEN1,EGR2,PAX6,MYRF,IL34,MECP2,ADGRG1,PTPRZ1,NCSTN,NF2,EIF2B2,HEXB,AKT2,P2RY1,SRSF1,CCL3,SLC25A46,LARGE1,DAG1,LAMB2,PTPN11,HDAC11,IFNGR1,CDK5R1,CDK6,GPR37L1,TLR4,VEGFC,PAFAH1B1,LPAR1,GPM6B,NDUFS2,EPHA4,BMERB1,IFNG,TP53,DLX1,MMP14,RRAS2,P2RY12,ID4,CSK,HAPLN2,GPR17,LEPR,CNP,TLR2,SOX9,RHEB,NDP,CNTN1,VPS54,PICK1,DICER1,SOD1,CCL2,DISC1,PTEN,NDN,ILK,DRD1,NAB1,MAP2K1,PLP1,TUBA1A,RB1,CLU,COL3A1,SOX2,MIOS,AKT1,CDK5,IL1B,MOBP,TPPP,S100A8,HRAS,AGER,WASF3,DUSP10,FKRP,GPC1,CERS6,KRAS,TNF,KCNJ10,RAF1,CX3CL1,TGFB2,ASPA,NAB2,BOK,CDKN2C,NKX6-2,CTNNB1,FGF10,EIF2B3,CNTNAP1,FA2H |
| 1.795e-04 | -8.63 | myeloid leukocyte activation | biological process | GO:0002274 | 155 | 67 | 18204 | 5365 |
TMEM229B,RHOH,LAT2,PSEN1,LCP2,TGFBR2,IRF4,LTBR,AIF1,IFI35,LILRA2,CBL,IL4,KIT,MYD88,TRAF6,TLR2,SNAP23,TLR9,KCNJ8,CHGA,PRKCE,CPLX2,NMI,MIR181C,IL15,TYROBP,PTGDS,JAK2,TICAM1,VAMP2,TLR1,BATF,TLR4,IFNGR1,PIK3CG,PYCARD,AGER,TLR6,ITGB8,FCGR2B,CSF2,VAMP8,CCL3,IL18,HMGB1,SYK,CLU,IL13,VAMP7,TMEM106A,CAMP,HYAL2,CX3CR1,MRGPRX2,TRAF3IP2,IFNG,RBPJ,KARS1,FCER1G,TLR3,CX3CL1,TNF,CCL5,CXCL8,FOXP1,NOTCH2 |
| 1.795e-04 | -8.63 | S1PR4 (sphingosine-1-phosphate receptor 4) | protein interactions | 8698 | 136 | 58 | 19454 | 5460 |
ATP2B4,TMED1,RINT1,TMEM87A,EMC2,RAB13,EMC8,PSEN1,IPO8,PREB,SLC29A1,YIPF3,LBR,KDELR1,MPDU1,SLC39A10,TSG101,ATXN10,EIF2B5,DERL2,ARL6IP5,NOP9,RMND1,MSMO1,SIVA1,SYNJ2BP,FAM241B,OSBPL8,TSPAN15,ATP2C1,TMEM160,TBC1D24,CMTM6,CERS2,CERS6,ABCC2,FUT8,TOMM22,YIPF5,SIGMAR1,GHITM,SAMM50,GOLGA5,PITPNA,CAV2,LEMD3,TM9SF1,SLC1A1,SLC30A7,ACP2,NDUFAF4,TNPO3,CNTNAP1,TM9SF4,CNNM4,SLC30A5,ATP1A3,XPOT |
| 1.795e-04 | -8.63 | CSTF3 (cleavage stimulation factor subunit 3) | protein interactions | 1479 | 136 | 58 | 19454 | 5460 |
STAU1,RPA3,MIRLET7I,HSPA8,SQSTM1,EP300,CD46,RPA2,FEM1A,MIR21,ATG16L1,TIMMDC1,DAPK3,SNRNP40,BMP1,CSTF3,ESR2,LMBR1L,FAIM,CPSF1,METAP2,CYP1A1,MYO6,CDC73,RIT1,PAPOLA,CUL3,AR,CPSF2,H3C1,SEPHS1,COPS4,FAF1,PABPC1,BAG2,NUPR1,TBK1,E2F4,CSTF2T,GTF2E2,FZR1,HNRNPL,TOP1,MIRLET7G,CDK9,PAPOLB,MACROD1,WIF1,CDC5L,SSU72,FBXO32,SNRNP70,AHSA1,MMUT,XPO1,HNRNPA1,DAG1,GAPDH |
| 1.795e-04 | -8.63 | FAM83B (family with sequence similarity 83 member B) | protein interactions | 222584 | 136 | 58 | 19454 | 5460 |
LAMP2,DPP4,ATG9A,RAB5C,YWHAG,YWHAH,LAMP3,RHOG,ARMC8,YWHAB,RAB35,ARL11,GJA1,KRT8,RAC2,ARF6,RHOH,STX6,LMAN1,DIRAS3,SLMAP,CAV1,ANKRA2,CSNK1E,RP9,PNMA2,RAB4A,RND3,KRAS,RAB3B,FLOT1,RAB2A,RAB11A,SFN,DNAJC5,PPP1CC,LAMTOR1,YWHAZ,BICD2,RHOB,UBE2H,RHOJ,ESR2,CDC42,RND2,PAK5,CSNK1A1L,ARL15,CSNK1A1,RHOU,DVL2,RAB9A,AKAP1,RAB5A,RNF113A,PFKFB2,STX7,TOMM20 |
| 1.795e-04 | -8.63 | ROCK2 (Rho associated coiled-coil containing protein kinase 2) | protein interactions | 9475 | 136 | 58 | 19454 | 5460 |
CDC5L,ZBTB2,RHOH,ARF6,SEC23A,ADD1,GJA1,CORO1C,HRAS,DFFA,RHOG,SMAD4,ANKRD49,LAMP3,NDC80,LAMP2,ADD2,PFDN1,KRAS,SLC39A7,TRIP4,PPP1R12A,RHOBTB1,STK16,MTA2,STRBP,NCKAP1,APEX1,RPL10,VIRMA,ROCK1,ACTB,RHOJ,MED17,LURAP1,OPTN,KCNJ2,RHOB,LAMTOR1,RACGAP1,DNAJC8,TYW3,RAB11A,CDKN3,CUL3,RAB2A,LZTFL1,STAU1,EGFL7,EP300,GPHN,HSPA8,RPA3,DNAJC3,FGFR1,LMNA,RPA2,FBXO42 |
| 1.812e-04 | -8.62 | ADP signalling through P2Y purinoceptor 1 | REACTOME pathways | R-HSA-418592 | 25 | 17 | 10285 | 3229 |
GNG10,GNG7,GNA14,GNB4,GNAQ,GNG11,GNG5,P2RY1,GNG3,GNA11,GNG13,GNB1,SRC,GNGT2,GNB3,GNG2,GNG12 |
| 1.815e-04 | -8.61 | MCM3 (minichromosome maintenance complex component 3) | protein interactions | 4172 | 334 | 124 | 19454 | 5460 |
FBP1,TP53,GINS4,MINDY3,ILF2,PPME1,NUPR1,MAP1B,FAF1,HSD17B10,LIPA,CCL2,FBXO25,RIGI,ORC5,CSNK2A1,COPS5,HDAC6,SUV39H1,TPM3,TSNAX,DCUN1D1,FZR1,TOP1,PTP4A3,TMPO,CDC5L,SPTBN1,ATG16L1,CCND1,CDK7,RPA2,JUP,METTL14,HSP90B1,GRM2,UBE2M,HNRNPH3,DVL2,BAP1,SOD1,SNCG,RPA3,HNRNPH2,TCEA1,PDHB,IRF7,FBXW7,BCL6,SMARCA5,AR,TXNIP,ZBTB38,UBE2H,CCNF,TSSK1B,PTEN,NDN,PPAT,VIRMA,UBA3,RAF1,YIPF3,PPP2R1A,EZH2,PDHA1,CHMP4C,POLR2D,MOB3C,SLC39A7,RPAP3,RABGGTB,KRAS,HNRNPF,MCM6,RAD21,SSRP1,TFG,RFC3,YWHAG,DDRGK1,AGR2,FKBP4,MGMT,PPP3CA,PHB1,SUMO2,SPTAN1,EGLN3,CEP19,WDR44,NUP62,RRAGA,PPP1CB,NEK7,PAK2,MAP2K1,PIH1D1,RFC4,HDAC5,CRY1,DDX5,PSMA3,EP300,CYFIP2,UFL1,MCMBP,STAU1,MYC,CUL2,CUL3,BTF3,MCM3,MCM4,BRCA1,HSP90AA1,CDKL2,RIT1,DLST,NFKBIA,CDC7,STAT1,RBBP4,ESR2 |
| 1.815e-04 | -8.61 | CLTA (clathrin light chain A) | protein interactions | 1211 | 334 | 124 | 19454 | 5460 |
DPP4,MOV10,MICB,HDAC6,COPS5,EDC3,NOS1AP,DNAJC7,MYBL2,TES,SEC23A,FCHO2,RPSA,TP53,TNRC6C,MAP1LC3B,TFRC,ACTR2,CAPZA2,TAB2,AP1S2,RNF8,PALM2AKAP2,STX8,NSDHL,LSM4,TCP11L2,TOLLIP,FN3KRP,VTA1,MEPCE,CAPZA1,RPL7A,PYCR2,SEC13,DNAJC5,NONO,LSM6,IGF2BP1,AP2A1,UBE2H,MAPRE1,CCNF,VAMP3,RPS3,SMAP2,WDR45,STX10,CHMP5,DYRK1A,RPS14,ATG16L1,CD2AP,CFTR,SYNRG,AP1AR,PICALM,LSM2,STAMBP,BAP1,RETREG2,TWNK,YKT6,FBXW7,PIAS1,CHMP2B,RGS2,PIK3R1,CTNNB1,CBL,MAP1LC3A,AFTPH,HNRNPL,OCRL,LSM5,CHMP2A,TOP3B,RAF1,EZH2,VPS33A,RAB4A,CHMP4C,STX12,ENPP4,SART3,AP2S1,HGS,MOB3C,SCYL2,LSM14A,HNRNPA2B1,UBE3A,BAG2,DCP2,AP1M1,RPS27A,TFG,TMEM38B,TMED5,MYC,CUL3,BTF3,MAP3K21,PSMD1,BAG3,PNRC1,MYO6,RPS26,DNAJB6,MIDEAS,AP2M1,TRIM29,TAX1BP1,PARL,ESR2,MAD2L2,ATP6AP2,PPP1CB,NANP,HSPA8,TXNL1,ZNF692,STAU1,ADRB2 |
| 1.819e-04 | -8.61 | GPX_AS | interpro domains | IPR029759 | 7 | 7 | 18521 | 5414 |
GPX4,GPX5,GPX2,GPX7,GPX3,GPX1,GPX6 |
| 1.819e-04 | -8.61 | Toll-like_receptor | interpro domains | IPR017241 | 7 | 7 | 18521 | 5414 |
TLR5,TLR6,TLR3,TLR4,TLR2,TLR1,TLR10 |
| 1.824e-04 | -8.61 | TUBGCP4 (tubulin gamma complex component 4) | protein interactions | 27229 | 165 | 68 | 19454 | 5460 |
IMMP2L,TRIM63,KCTD17,KRAS,CTNNBL1,MRPS18B,RPL3,TCOF1,UQCC2,RUSF1,TUBB4B,CD2BP2,TUBA1A,ATP5PB,MRPS23,CDC5L,OPRL1,RPL7,RPS16,RPLP2,HSD17B11,YBEY,MGME1,POU5F1,PDCD1,TUBG1,MZT2B,P2RY10,ATP5MG,HSPA5,MRPS7,SLC5A6,MRPL41,HSPA8,SLC22A6,RPL27,RPA3,RNF146,SIGMAR1,WWP1,PAK5,RPRD1B,RPA2,SYNRG,NUDT3,HCST,TOR1AIP2,CHIC2,APLNR,UBB,RPL35,TXNDC12,TUBB,COPE,TRIM27,CHRM4,PELO,RPS3,RIT1,IGF2BP1,STN1,FBXW11,PHKA1,CCDC85B,OPRM1,GPR17,CUL3,PYCR1 |
| 1.836e-04 | -8.60 | regulation of anatomical structure morphogenesis | biological process | GO:0022603 | 894 | 312 | 18204 | 5365 |
SPRED1,PDCD10,PPFIA2,IL1A,MYL12B,TGFB2,MAP1B,FGF10,CTNNB1,TNFAIP3,RALA,MIR9-1,CCL24,MT3,ADAMTS1,PPP3CA,WNT7A,IL1B,SPP1,DKK1,KLK3,SEMA5A,WASF3,ARHGAP15,GREM1,MTDH,PTEN,MIR29C,SMAD1,ATP2B4,NRP1,STAT1,FGF1,MIR125A,HGS,PRKCB,MAP2K1,L1CAM,DVL2,CD34,FGD2,RGMA,PROK1,GHRL,MIR20A,XBP1,CDC42EP2,MIR377,RLN2,PID1,SOX9,KIT,STAT2,TNR,TGFBR2,MIRLET7B,PLAA,MIR130A,PAK2,MIR221,FIS1,SNAI2,DLG1,MIR492,MSN,AR,RND2,IFRD1,FITM2,FOXP1,MIR106B,CST3,ZDHHC15,EFNA3,UBE3A,FGR,TLR3,EPHA4,MIR185,SFRP1,MIR126,IL6,FERMT2,SDC2,MIEF1,AGO1,HSPB1,ZMYM4,BTG1,CCL3,PLXNC1,YWHAH,PRL,OTX2,MARCHF5,FUT1,MIR885,MIR1224,MOV10,AKT3,MIR132,TGIF2,UST,BVES,SPRY1,MIR10A,DAPK3,ZMYM3,CFL1,VEGFC,MTCH2,EMC10,TMBIM1,CDC42SE1,CDK5R1,TSPAN18,PLEKHO1,SIPA1L1,CDC42EP4,CMA1,MIR210,CAV3,EFNA5,MEF2C,SEPTIN7,SMURF1,RUNX1,ZMPSTE24,ADM2,RTN4,EMP2,MIR31,RGCC,BRCA1,LST1,JAK1,GPRASP3,SYT4,ANAPC2,MIR375,PSEN1,MIR146A,TNIK,MIR21,MIR30B,MIR505,SARM1,TNF,CCR3,ROCK2,IL10,MIR640,MUL1,MIR1298,TBCCD1,MIR24-1,GLUL,CX3CR1,MIR145,CCM2,MSX1,WNT2,SLC23A2,TFRC,DDAH1,FGF7,FGF16,CORO1C,MIR495,MIR205,CD40,MINAR1,CDK5,NTNG2,PTK7,CDC42SE2,CLDN4,EPHA2,CXCL12,RHOU,BCL6,HECW1,HDAC6,TRIM46,NOG,CXCR4,ITGB8,TBC1D24,EMILIN1,RHOB,MIR23A,ZNF304,MIR361,STK11,CCL2,CHI3L1,DISC1,CFDP1,CXCL10,NHERF1,PALM2AKAP2,PML,JMJD8,TERT,MIR16-1,COCH,FGF13,ADNP,MIR424,MIR214,MIR17,NEFL,GJA1,PRKCA,CYP1B1,SLC12A2,MIR222,GADD45A,AGGF1,CCR2,F2,FOXC2,GAS2,CLDN3,NTN4,CDC42EP3,NINJ1,MIR378A,CYRIB,TIAM1,LPAR1,CXCL8,IL17F,MIR34B,PAFAH1B1,FKBPL,NLGN1,MIR1-1,SYNJ2BP,ROCK1,MIR15A,SYT2,LGR4,MIR143,MIR34A,CAMP,CRABP2,VASH1,MIR99B,TNFSF12,FGFR1,P2RY1,SRC,MIR34C,DAG1,PAX9,HUWE1,PHB2,CCL11,KLF4,DLG4,FASLG,LEP,APLNR,PIK3CG,THY1,MIR939,EPS8,KRIT1,MIR137,NFE2L2,HSPB6,MECP2,SLITRK1,BMPR1A,VEGFA,MIRLET7G,SEMA7A,BMPR2,GTF2I,HEXB,CHRNB2,CHRNA7,ADCK1,NF2,MIR29A,F11R,MIR193A,GAB1,NR2E1,RAP2A,MKLN1,RHOG,MIR30E,AMIGO1,RHOJ,PQBP1,GPNMB,JUP,FZD4,MIR212,NTRK2,PPARG,STIM1,MIR503,NIBAN2,SP1,ZMYM6,PGK1,CXCL13,MIR30A,MIR153-1 |
| 1.838e-04 | -8.60 | SAP18 (Sin3A associated protein 18) | protein interactions | 10284 | 291 | 110 | 19454 | 5460 |
EIF4A3,MAGOHB,VIRMA,SMARCA5,FBXO7,NTAQ1,AR,PPP1CC,PHKA1,TADA3,CCDC22,PPIG,MAPRE1,CASC3,UBE2H,PML,RNF113A,KDM1A,MBD3,SF3A1,LMNA,ALYREF,RGS10,MRPL50,TOP1,RBM42,CDC5L,ZBTB2,DPP4,ATP5MG,API5,ZMYND11,SNRNP70,SLC35A1,NOL12,BRD3,SNIP1,SEPTIN7,SOS2,PSMA5,CDC40,CAMKV,THRAP3,EIF3E,ING1,SURF4,IK,TOPORS,NUPR1,RAN,DLST,SMU1,SNRPD2,PHKB,MATR3,ACTB,RBBP4,SNRPB2,ESR2,MYC,HNRNPC,SFN,PSMD1,SNRPB,ATG3,LMNB1,ARMT1,RIT1,SNRPA,DDX39B,UPF3B,SF3B1,TRA2B,SSR3,SAP18,ACTL6A,SUFU,ZC3H14,ADNP,SIN3A,SRSF1,SPTAN1,SRSF10,IFI16,TRA2A,DDX23,HNRNPD,MAGOH,ARGLU1,SRSF8,SRSF7,RTCB,TFPI,KRAS,RBBP7,VDAC1,SSRP1,ZNF263,RAF1,TOP3B,E2F4,NCSTN,ANAPC13,SAP30,SKA3,EZH2,NFKBIL1,CHMP4C,MTA2,SMARCB1 |
| 1.840e-04 | -8.60 | regulation of RNA stability | biological process | GO:0043487 | 281 | 111 | 18204 | 5365 |
MIR204,MIR423,MIR181C,CNOT7,RC3H2,FASTKD5,MIR137,ZCCHC17,IREB2,DXO,EXOSC3,MIR195,YTHDF2,MIR210,MIR342,MIR106A,MYD88,SYNCRIP,ALKBH5,TNFRSF1B,MIR625,DCP2,MIR100,MIR193A,MIR96,MIR30B,METTL14,MIR519D,MIR146A,MIR149,MIR212,PCBP4,RNASEL,MIR185,TENT5D,APEX1,MIR106B,THRAP3,MIR34B,MIR223,PAIP1,MIR135B,PHAX,MIR142,AGO1,TRAF3IP2,ROCK1,MIR1-1,MIR885,MOV10,CNOT8,MIR340,NRDE2,MIR26B,MIR190B,TENT4A,MIR140,MIR130B,CARHSP1,MIR125A,TIRAP,MIR708,IGF2BP1,TENT5C,MIR200C,MIR424,PABPC1,HNRNPC,ZC3H14,MIR491,MIR16-1,MIR206,FXR2,MIR373,MIR181D,PRKCA,MIR214,HNRNPA0,CIRBP,MIR20A,MIR320A,MIR497,VIP,CNOT6,MIRLET7B,MIR130A,MIRLET7C,MIR24-1,MIR192,ROCK2,DKC1,CNOT2,PDE12,CNOT6L,MIR9-1,TNRC6C,HNRNPD,MIR191,TRAF2,MIR145,DHX9,AKT1,BOLL,ELAVL4,YTHDF1,MIR495,MIR23A,MIR211,MIR98,LARP4B,EXOSC8 |
| 1.845e-04 | -8.60 | ZNHIT6 (zinc finger HIT-type containing 6) | protein interactions | 54680 | 83 | 39 | 19454 | 5460 |
SRFBP1,TUBB4B,TAF2,PML,LGI1,PRIM2,SNAPC1,RUVBL2,RUVBL1,KDM1A,KRAS,COPS4,ASB3,FTL,SNRPG,PTGES3,CMAS,TRIM52,CUL3,CDC16,UBXN6,F9,ZNHIT3,MED10,KPNA1,SMAD2,ZNHIT6,CIB2,FBLN5,EEF1AKMT3,CCNF,PRMT5,PRNP,TUBB,ZCCHC7,NOP58,FZR1,EGLN3,NAA11 |
| 1.845e-04 | -8.60 | SYT1 (synaptotagmin 1) | protein interactions | 6857 | 83 | 39 | 19454 | 5460 |
TSHR,UBIAD1,ATG16L1,CYB5B,SDC2,VAMP2,PPARG,EIF2B3,RBM18,SV2B,TMEM254,RAB27A,VLDLR,IRF3,ZDHHC17,TMEM60,GPM6A,CSGALNACT2,FGF1,HMOX2,DNAJC5,CREBBP,SMAD2,STX1A,HAX1,RRP7A,BTN2A2,SYT4,SYT2,SYNCRIP,SIN3A,ARMC1,CD63,RAB33A,CHGA,EIF2B2,SNAP25,EIF2B5,PRNP |
| 1.845e-04 | -8.60 | APOOL (apolipoprotein O like) | protein interactions | 139322 | 83 | 39 | 19454 | 5460 |
SPOP,HTRA2,PMPCA,STOML2,SLC25A46,BAZ1B,STARD7,SLC25A12,PARL,CHCHD3,ATP5PD,EGLN3,COX4I1,DUSP6,AIFM1,CHCHD6,SLC1A1,RMDN3,AQP3,SAMM50,RPA2,COX6C,ATP5PO,CARD19,NDUFA12,MTCH2,MTX2,DDAH1,ATG16L1,APOO,SLC15A1,SLC25A51,CLEC12B,PHB2,CHCHD2,IMMP2L,SFXN1,SLC39A9,ATP5F1E |
| 1.845e-04 | -8.60 | INO80 (INO80 complex ATPase subunit) | protein interactions | 54617 | 83 | 39 | 19454 | 5460 |
RPA2,ACTL6A,TOP3B,ELF1,EGR2,ACTN4,TUBA1A,RPL4,STAU1,RUVBL1,GTF2I,CA10,MBD3,RPA3,TFPT,BAP1,LRTM2,INO80C,HSPA8,RUVBL2,H2AC4,BRD3,RIT1,POU5F1,INO80E,SMARCA5,ACTL6B,BCL7C,ACTB,PLEKHF2,KLF9,VIRMA,ESR2,APEX1,TUBA1B,STUB1,BRD9,FGFBP1,PRMT5 |
| 1.846e-04 | -8.60 | intracellular signal transduction | biological process | GO:0035556 | 1505 | 505 | 18204 | 5365 |
RAB4A,DYRK2,DEFB124,TLR3,SOS2,DOK6,ZNF207,RGS19,G3BP1,PLA2G4B,CDC20,CDC42,DAPK1,FZR1,DUSP19,SOCS2,HSPB1,CRYAB,NUPR1,MYC,FLCN,IGF1R,CREB1,IER3,SCG2,BCL10,HTR2A,RPS6KA4,CDK1,RAB9A,CCL3,MIF,RAB18,GDI2,CFL1,STK3,PDE7A,BTN2A2,SOCS4,SMAD5,MAP3K12,TAB1,SHC3,DEPDC1B,CDIP1,USP8,DOK4,PPP1CB,CAV1,RBBP8,SOCS3,MCOLN1,PRDX4,TYROBP,CLIC2,MEF2C,CAV3,FKBP1B,CD28,MYD88,SMAD2,BRCA1,HTRA2,MDC1,SOCS5,ZMPSTE24,CD4,RPS27L,MIR146A,PSEN1,MTM1,ARL6IP5,IGFBP3,MAP2K3,CHP1,PAK6,CRIP1,SRPK2,NOTCH2,KRAS,POLB,PDE1A,CD209,TF,SH3BP5L,TRIM8,DEFB1,RIT1,SESN3,FGF10,SPC24,GSTM2,BTBD10,RAP2B,PDE8A,CXCR6,CREBBP,CXCL1,GREM1,CCR6,CCR7,CDH13,DDIT4,RNF8,CDC5L,RIT2,PRPF19,NABP1,CD200R1,RASGRP2,NCKAP1,SMAD1,ATP2B4,EIF4EBP2,GRAP,MAD2L1,TLR7,RAP1B,DIRAS3,IGFBP4,MAP3K14,SHC1,MAP1LC3A,PPP1CC,PRKCB,CCR1,MAP2K1,ERO1A,CCR5,SOX9,RHEB,NFE2,ATP1A2,RAB13,DLG1,BECN1,TOPORS,ATP1B1,STK4,FKBP8,MAEL,TP53,RRAS2,SDCBP,RRAGA,MDM2,CXCL8,DDX5,SOD2,FHIT,VPS4A,HPCA,PPP1R1A,MIR1-1,MAP3K3,SYNJ2BP,NKIRAS1,RAP2C,ARHGAP1,FGFR1,RAB30,ACKR3,ITGAV,RAD1,TMEM38B,RAC2,DDIT3,TLR4,IFI6,CCL11,PTPN11,IKBKB,CUL2,HINT1,ITK,PPP2R1A,SESN2,ASB7,PRKCQ,RHOG,IRAK4,RHOJ,KLHL22,RAP2A,STK24,RABIF,IMPACT,PDE9A,CDKN1B,PTGER4,TP53TG5,CCNA2,CAP2,RAB39B,RACGAP1,UFL1,LIPA,CHMP4C,RAF1,ROCK2,MAP3K11,CCR3,TNF,PRKX,EDA2R,PPP1R1B,RPA2,ANP32A,CX3CR1,CCM2,TRAF2,FBXO31,ATP1A1,EPHA2,BCL6,RHOU,TOPBP1,ELMO1,CXCR1,DNAJC10,STUB1,DDAH1,PYCARD,HRAS,MAPK10,ERAS,DUSP10,BATF,RHOB,CAB39,CXCR4,HINFP,ZNF622,CIDEB,CDKN1A,INPPL1,TBC1D10C,CGAS,STRADB,RB1,CITED1,IK,ADNP,ILK,NKIRAS2,CASP4,GUCY1B1,H2AX,STK38L,NLRP3,CEBPG,KCTD9,CXCR3,PPM1D,PRKCA,RGL1,RAB9B,RHOH,MAPKAPK3,RASGEF1C,TIFA,CCR2,AIF1,PDE6A,BRAP,MYO6,G3BP2,PEA15,RTKN,BAX,TRAF3IP2,AKT3,ERRFI1,ROPN1B,JUNB,AKT2,PPP1R17,JUN,FLOT1,DAPK3,PAK5,WSB1,SPRY1,OXSR1,GRAP2,CARHSP1,NEURL2,ZBTB33,BCL2A1,EDNRA,VAV2,MAD2L2,ADCY3,RERG,PMAIP1,CD36,BABAM1,PNPLA8,CD80,CDC42EP4,MCL1,JAK1,HACD3,TNFRSF1B,TLR9,PLCB1,TNIK,SFN,LCP2,PRKD3,PIK3R3,KARS1,BOK,TAX1BP3,EP300,NFKBIA,IGF1,PDCD10,RALA,GPX1,OXTR,CTNNB1,NPR2,BAK1,TNFSF15,NOP53,DELE1,AIFM1,AKT1,SIAH2,IL1B,NDNF,CEBPE,KBTBD2,PPP3CA,ASB3,RPL26,FKRP,GRB10,SMAD4,TANK,NYAP2,MAPK4,TLR6,IRAK1BP1,NCALD,PPP3R2,BCL2L1,JAK2,PPP5C,PTEN,BAD,ATF1,LCP1,DVL2,CDK5RAP3,CRY1,ADCY2,PRKCE,MLLT11,KIT,CDC42EP2,CREBZF,BUB3,RRN3,RND2,AR,SLC8A1,CRKL,LAT2,PSMG2,CCND1,SS18,STK26,TGFBR2,MSH6,PAK2,MAP3K21,PLCL1,TAB2,DOK5,TMEM117,ARHGAP5,PAFAH1B1,GNB1L,NUDT4,PIK3CA,DTL,TIAM1,P2RY12,ROCK1,MEF2A,ASB11,SRC,ADRA1A,KCNJ11,LAMTOR3,PRDX1,PIK3CG,ATF4,KRIT1,EPS8,PDE4B,RAB40AL,LEP,SQSTM1,FIBIN,PLCB2,PSEN2,FGF23,ARHGEF6,RCE1,IVNS1ABP,NDC80,PDE1B,SMAD9,NFE2L2,NF2,LAMTOR2,ADGRG1,RGS6,YWHAZ,GSTO1,RND3,PRKACB,PIK3R1,RAPGEF5,PIK3R2,SBK2,CUL3,RFXANK,SHOC2,GARRE1,RASGRP3,NBN,CAMK1,TLR8,IFI16,ASB8,SMAD3,RAB33A,ASB1,SELENOK,RASD1,LACRT,RHOBTB1,BIRC2,RAB33B,TFRC,COL1A2,RHBDD3,RAP1A,CISH,RALB,SAV1,NUF2,CD40,TMBIM6,SYK,RINT1,CCR4,GNB1,STK11,CREB3,STK38,RGL2,NFKBIL1,NKX3-1,RASL10A,PRR5L,RPAP2,PML,MAPKAPK5,PDE2A,MAP2K6,NPPC,CHI3L1,DISC1,HCLS1,DUSP6,FOS,OPRL1,MRAS,FGF13,EIF2S1,CRADD,KCNJ8,CHRM3,NFKB1,TRAF6,GADD45A,TLR2,NAE1,CYP1B1,DMPK,LAMTOR1,CD2AP,DUSP9,PLN,GSKIP,TBK1,TRIB1,CDC42EP3,RAB35,P2RY11 |
| 1.852e-04 | -8.59 | ACADM (acyl-CoA dehydrogenase medium chain) | protein interactions | 34 | 139 | 59 | 19454 | 5460 |
DDRGK1,YWHAG,PIK3R1,HSPB1,AHSA1,MRPS26,ATP6V1A,GATD3,SSBP1,ESD,CAND1,FAF2,PPP2R1A,GFPT1,TP53,ETFB,E2F4,DISC1,PDHA1,RPN1,COX8A,HSPD1,SAR1B,IMMP2L,MEPCE,AP1M1,ARF4,VDAC1,ETFA,AKAP12,DYNC1I1,GALE,HMOX2,CUL3,LDHB,CTSD,RAB2A,MTG2,ATP1A1,CCNF,VDAC2,ARF1,UQCRC2,SEC63,SUCLG2,TECR,SCML2,LDHA,FAXC,CDC42,SLC25A3,MTRES1,HSP90B1,ACAA2,IDH3A,DDX39B,RPA3,RER1,UFL1 |
| 1.867e-04 | -8.59 | DNAJB6 (DnaJ heat shock protein family (Hsp40) member B6) | protein interactions | 10049 | 359 | 132 | 19454 | 5460 |
RPL6,HSPB8,YWHAH,XPO1,YWHAG,MAP3K14,NT5C2,IQSEC1,DDRGK1,CDK5RAP3,WDR12,SLC25A28,DNM2,MRTO4,PHB1,NRSN1,SNX1,SNX2,NTMT1,EGLN3,HSP90AB1,RAF1,NAA15,SOX2,ISG15,ASPM,TUBA1A,NIM1K,TUBB4B,HDAC11,DNAJB4,BAG2,GNL1,PRPS1,SSRP1,SAR1B,MYC,CUL3,CUL2,MAP3K21,BAG3,GALE,MLF2,BRMS1,BLVRA,FTSJ3,DCAF4,LMNB1,MYO6,HSP90AA1,RCL1,MATR3,RPL7L1,RBBP4,ESR2,APEX1,EHD1,ETF1,NACC2,MAP2K1,GAMT,DNAJC3,HSPA8,STK26,TTC1,MCMBP,DNAJB2,HDAC6,GAPDH,SNRNP70,AKAP8L,DNAJC7,PTPN1,PWP2,RGS10,SURF6,KBTBD4,TP53,SLC29A1,RPL15,PGM1,PIK3CA,RBM34,PPME1,NUPR1,MAP1B,RNF20,FKBP8,RIGI,RPF2,NAA50,HSPA14,AKT1,MLF1,PTPN11,CIAO1,FBXO7,RPL26,HMOX2,SKAP2,RC3H2,STUB1,CYRIB,TUBA1B,DTYMK,QSER1,PTEN,F11R,BCCIP,NOPCHAP1,COQ8B,ATG16L1,CCND1,PPP1R8,POLR1D,CFTR,IDH2,PICALM,UTP15,UBE2M,PPM1G,NLE1,TMEM263,RNF113A,TCEA1,ARFIP1,WDR3,RPL4,FBXW7,USP8,GRPEL1,HSPA5 |
| 1.876e-04 | -8.58 | MRPL33 (mitochondrial ribosomal protein L33) | protein interactions | 9553 | 54 | 28 | 19454 | 5460 |
MRPL10,RBMS2,MRPL12,MRPL47,MRPL51,MTRES1,MRPS18A,PGK1,RETREG2,MRPL22,MRPL20,MRPL9,RIOK2,ATG7,MYC,UBE2H,SKIC8,MRPL18,SNRNP70,MRPL13,LDLR,MRPL53,SYNCRIP,PSMB6,CNTROB,MRPL24,MRPL23,MRPL50 |
| 1.876e-04 | -8.58 | ADP signalling through P2Y purinoceptor 12 | REACTOME pathways | R-HSA-392170 | 23 | 16 | 10285 | 3229 |
GNAI3,GNG3,GNB1,P2RY12,GNG13,GNB4,GNG7,GNG10,GNG5,GNG11,GNG2,GNG12,GNAI2,GNB3,GNGT2,MIR197 |
| 1.883e-04 | -8.58 | nuclear speck | cellular component | GO:0016607 | 414 | 154 | 19108 | 5553 |
SF3A1,JADE1,HDAC5,SART3,PSPC1,FAM76B,CHTOP,RING1,ZC3H14,SNRNP40,NR0B1,HP1BP3,CACNB4,EIF4E,TMEM179B,OIP5,PPP1CC,CSNK1A1,CASC3,AIPL1,PIAS1,LUC7L3,GTF2H2,API5,PRPF31,TCIM,GTF2H4,CBLL1,GADD45A,RFXAP,MORF4L1,RNF113A,THRAP3,CD2BP2,SLU7,DHX15,ALYREF,WTAP,ATF4,DDX39B,COP1,ZBTB18,CNOT7,EAF2,PIP5K1A,RMI2,SRSF10,NRDE2,HIKESHI,RADX,NONO,IFI16,POMP,LMNA,DDX5,ABHD17A,RSRC1,TRIM22,SCNM1,S100PBP,TREML1,NXT1,OGG1,CDC40,TOPORS,UNC45A,HECTD1,THOC2,CWC15,CDC5L,RCHY1,SNRPB2,AKAP17A,FYTTD1,SPOP,SRSF12,PPIG,POLR2D,PRPF4,SMNDC1,IL15,SNRPA1,APEX1,SMU1,PPIH,RNF34,TAB1,ALKBH5,PRCC,ZBTB16,PRPF18,DYRK1A,HBP1,SAP18,NCAPG2,DDX39A,VPS72,HSPB6,PHF7,POLDIP3,HEXIM2,SRP54,PSKH1,MAGOH,FAM107A,DDX42,RBM15B,PQBP1,BNIP3L,PLCB1,NR4A2,ASCC1,TERT,FBXL4,CDK12,PRPF19,SURF2,MEF2C,SNRNP70,THOC3,ATPAF2,LPXN,PPP1R8,TFIP11,SOX2,SRSF8,FAM193B,AR,SRSF4,AKAP8L,SMC4,H2AX,THOC6,SF3B1,THAP7,SUMO1,SRPK2,SRSF2,DDX46,VIRMA,ABITRAM,MSX2,CXXC1,THOC1,UHMK1,EIF4A3,IK,SRSF7,INPPL1,COPS4,SIRT7,SRSF1,RBM27,TAF5L |
| 1.886e-04 | -8.58 | response to metal ion | biological process | GO:0010038 | 343 | 132 | 18204 | 5365 |
MT2A,BECN1,CUTA,VPS54,CYP1A1,PLSCR1,ATP1A2,NPTX1,PPIF,HSD17B1,GRIA1,G6PD,MTF1,CD14,SLC12A2,KIT,EIF2S1,SLC25A24,ATP5F1D,MT1M,TERT,KCNIP2,MAP1LC3A,GSK3A,SUMO1,CYP11B1,ATF1,OGG1,TUBA1A,ALOX5AP,RASGRP2,SLC11A2,PPP5C,FOS,GLRA2,HSP90B1,CPNE2,ACO1,FBP1,S100A8,MT1E,AMELX,GCLC,PPP3CA,SLC6A1,HFE,AKT1,KCNMA1,ADD1,CRHBP,SLC1A1,HNRNPD,CYP2R1,CYBRD1,PCNA,AANAT,TF,KCNMB1,MT3,TFRC,CRIP1,DPEP1,CYP11B2,SLC6A3,UCP2,KCNJ10,IL1A,CALR,FXN,AQP3,CPNE1,CLDN1,STIM1,DTYMK,NUDT1,FABP4,ALG2,TSPO,NQO1,TLR9,CDKN1B,KCNMB2,SLC25A12,GPHN,B2M,NCSTN,MEF2C,SLC41A1,KCNH1,MNAT1,MT1A,CAV1,MCOLN1,NFE2L2,AQP2,FGF23,MECP2,TXNIP,PRNP,FIBIN,HOMER1,MT1X,IMPA2,BACE1,NEUROD2,SLC25A23,ATF4,CER1,DLG4,PPP2CB,JUNB,JUN,HSPA8,SOD3,CDK1,TRPC1,HPCA,AHCYL1,CREB1,MEF2A,MMP9,BGLAP,NEK7,SOD2,KCNC1,MDM2,SLC13A5,KCNB1,GLRA1,CLIC4,TNNT2,NLGN1 |
| 1.886e-04 | -8.58 | NANS (N-acetylneuraminate synthase) | protein interactions | 54187 | 94 | 43 | 19454 | 5460 |
RPA2,CNDP2,AKR1A1,MLH3,FBXW7,EIF4E,RPA3,TLR2,FLCN,GLOD4,CKB,ATG3,STK11,HSP90AA1,MYC,FBXO7,BAG3,PRDX2,SRC,QNG1,CTNNA1,ABHD14B,RRAS2,PLS3,PIR,NHERF1,RAD23B,MVD,E2F4,MSH6,HAPSTR1,BCL10,AK2,AGR2,PDIA3,PRDX1,ODC1,POLE3,HSP90AB1,NPC2,UBE2N,RPLP2,FAHD1 |
| 1.886e-04 | -8.58 | AFG2A (AFG2 AAA ATPase homolog A) | protein interactions | 166378 | 94 | 43 | 19454 | 5460 |
PFDN2,MAPRE1,RIT1,FAS,SNRNP70,FBXW11,PSMD14,BRCA1,XPO1,P2RY10,DDRGK1,CFAP161,MYC,IFI16,FAM174A,PFDN5,CUL3,CDC5L,DYRK1A,VIRMA,MAD2L2,PRNP,SUMO2,PSMC5,CCNF,SSR2,AIFM1,CINP,RAN,HEXIM1,GRM2,CFTR,RPL15,ATG16L1,PSMC4,KBTBD4,SYK,PSMA5,KRAS,UFL1,HSPA8,RNF113A,BAP1 |
| 1.886e-04 | -8.58 | RP9 (RP9 pre-mRNA splicing factor) | protein interactions | 6100 | 94 | 43 | 19454 | 5460 |
LBH,H2AJ,TMEM14B,CBX3,SREK1IP1,RPL31,AP1M1,TOLLIP,FGF12,CSNK2A1,INO80E,IFI16,ANKRD50,UQCR11,NOS1AP,DDX23,DUSP6,FOLR1,PTP4A3,SUMO1,CAPN1,ZC3H14,EHHADH,ATG16L1,SDCBP,LMNA,RNF113A,NKAPD1,FTL,ANAPC15,MYC,UBE2H,FAM83B,CSNK2B,EZH1,OPTN,CCNF,TCEAL7,SH3BGRL,SNRNP40,SPCS1,IFI6,TAX1BP1 |
| 1.889e-04 | -8.57 | organelle membrane fusion | biological process | GO:0090174 | 98 | 46 | 18204 | 5365 |
BET1,YIPF4,YIPF5,CHMP4C,VAMP3,SYT4,STX17,STX12,VPS16,CHMP5,SNAP23,STX6,VTI1B,VIPAS39,SNAPIN,VPS18,CHMP2B,STX7,PLA2G5,CAV2,CHMP2A,VAMP2,STXBP1,STXBP6,STX11,VPS39,STX16,SNAP25,STX8,SNAP29,VAMP8,CHMP1B,STX1A,VPS33A,VPS4A,CLTRN,VAMP7,GOSR1,TOM1,CHMP1A,STX10,GOSR2,SEC22B,VCPIP1,VAMP1,STX5 |
| 1.896e-04 | -8.57 | HDAC9 (histone deacetylase 9) | protein interactions | 9734 | 75 | 36 | 19454 | 5460 |
SERPINA1,HBB,CTBP1,CAMK1,PPARG,MAPK10,RFXANK,JUN,SUMO1,TP53,SYK,BCL6,MEF2A,ZBTB16,HDAC3,HINT1,ZC3H11A,MEF2C,YWHAZ,H1-10,CAPG,HDAC6,MEF2B,SFN,ANKRA2,TMPO,CBX5,SUMO2,TRIM29,TOP1,CCAR2,ALB,HEY2,FOXP3,ETV6,SIN3A |
| 1.905e-04 | -8.57 | IRS4 (insulin receptor substrate 4) | protein interactions | 8471 | 279 | 106 | 19454 | 5460 |
RPA3,BAP1,RHOU,SIRT7,DERL1,NF2,KDM1A,PIK3R2,GABRA1,CDC42,CFTR,RPA2,HAUS2,CCNF,STUB1,PTEN,NDN,CTSB,RHOJ,RAB2A,PTPN11,FBXO7,USP14,SKAP2,RC3H2,UBE2H,CALU,CLPB,IGF1R,SOCS2,PTGES3,TP53,TFCP2,PIK3CA,FZR1,ARF6,STX6,CAV1,ZBTB2,LAMP3,GPRASP2,CSNK2A1,COPS5,TUBG1,AKAP8L,HSPA8,HDAC5,P4HA2,NMRAL1,RAB5A,UFL1,STAU1,STX7,G3BP2,RNF41,RND2,CDKN1A,PHF21A,PPP5C,MYC,SFN,CUL3,PIK3R3,CUL2,LAMTOR1,RHOB,YWHAZ,HSP90AA1,ILK,TESK2,G3BP1,KRAS,FLOT1,RAF1,TUBA1A,PPP2R1A,LGR4,PDHA1,RND3,OTULIN,CRKL,RNF126,WDR6,RAB35,PHB1,GJA1,MAP1LC3A,MAGED2,RHOH,DIRAS3,CACYBP,EGLN3,LAMP2,UBXN6,PIK3R1,SAV1,RAB5C,YWHAH,YWHAG,DDRGK1,RHOG,AGR2,HAX1,RB1CC1,HSPB1,YWHAB |
| 1.907e-04 | -8.56 | smooth_muscle | COSMIC cancer mutations | smooth_muscle | 53 | 28 | 16828 | 4835 |
CDH11,DICER1,EZH2,PIK3CA,PTPN11,AKT1,RB1,CTNNB1,SRSF2,EWSR1,SF3B1,NFE2L2,STK11,SS18,JAK1,HRAS,PTEN,TERT,JAK2,ETV6,CDKN2C,FBXW7,MET,KIT,BRCA1,TP53,IDH1,KRAS |
| 1.907e-04 | -8.56 | HK2 (hexokinase 2) | protein interactions | 3099 | 122 | 53 | 19454 | 5460 |
HEXB,TRIM36,RPA2,TOMM22,PXMP2,TOMM20,MARS1,IRF7,HSCB,SRM,STAU1,AKAP1,EP300,RPA3,SEPTIN6,EXD2,IRF3,FIS1,HSP90AA1,BRCA1,H2AZ2,MYC,CUL3,VIRMA,ZBTB17,BUB3,MGST3,PRKCE,LMBR1L,OPTN,CCNF,ENO1,PPME1,OTULIN,NUDCD3,MTCH2,VDAC1,SEMA4C,NDUFA4,FOXP1,IGFBP4,PROM1,SKIC8,SMAD4,TMA16,EMC4,EGLN3,COX14,SUMO2,XPO5,TES,ARL4D,PTGDS |
| 1.907e-04 | -8.56 | EXOSC7 (exosome component 7) | protein interactions | 23016 | 122 | 53 | 19454 | 5460 |
DXO,EXOSC3,EXOSC8,SOX2,ESS2,SUPT5H,TP53,CCAR1,VRK1,USP30,SNRNP48,DRG1,MPHOSPH6,TSNAX,SNRNP70,DIS3L,DDRGK1,IFI16,MRPL50,MIF,THOC1,FZR1,RPS16,EIF4E2,TFIP11,PALS2,RPA2,RALYL,ATG16L1,RBM22,STAU1,UBE2K,C1D,MTDH,NMRAL1,HSPA8,EXOSC4,DDX46,LUM,RPA3,RBM7,UBE2H,RIT1,EXOSC1,BICD2,DHPS,MYC,ESR2,IP6K1,PTEN,RSRC1,EIF2AK2,PSPC1 |
| 1.908e-04 | -8.56 | FEN1 (flap structure-specific endonuclease 1) | protein interactions | 2237 | 174 | 71 | 19454 | 5460 |
GLOD4,TDP1,MYC,FOXA3,AR,RAB14,APEX1,TNPO3,LMBR1L,CCNF,PARP2,ZNF330,ENO1,FOXP3,PTEN,PTCRA,RPA2,LMNA,CDK1,GSTP1,ARCN1,CHPF2,ACTL6A,DDAH1,NDUFAB1,SNRNP27,CCNA2,CFTR,DGCR8,EEF1G,FBXW7,BAP1,SOD1,RPA3,HSPA8,EP300,DRG1,MOV10,IFI16,HNRNPA1,TRA2A,RPL35A,PRNP,TOP1,CDC5L,HDHD3,UBE2N,CBX3,EZH2,CHMP4C,RAD1,CMPK1,ZNF263,RAF1,BUD23,RAP1A,SOX2,PGM1,GTF2E2,H3C1,SEM1,VRK1,PFDN1,DUSP19,RAD21,MSH6,TFG,SSRP1,RPL31,PCNA,HSD17B10 |
| 1.908e-04 | -8.56 | DUSP14 (dual specificity phosphatase 14) | protein interactions | 11072 | 174 | 71 | 19454 | 5460 |
EPHA2,IGF2BP1,CSGALNACT1,PYCR2,PYCR1,SAMHD1,ISCA2,ANKH,MATR3,TAB1,B3GALNT1,APEX1,DUSP3,ESR2,ACOX1,PRMT5,STX17,ZNF326,DRD3,LACC1,USP6NL,EDF1,KDELR2,FBXL4,FOXP2,MRPS7,LYG2,LGI1,FOS,HSPA8,NPSR1,TNFSF13,PTDSS1,MRPS35,ST6GALNAC3,ISYNA1,ATG7,ORMDL3,CBR4,HNRNPL,CPLX3,CCAR2,CD28,SRSF10,RAB39B,RAB11B,PTK7,SYNCRIP,FUBP3,SCG5,GATD3,OR51E2,CAPZA2,CCR1,FAM136A,GEMIN7,SGIP1,OTULIN,SRFBP1,SOX2,TRAF2,FNTB,HNRNPK,MRPS18C,TFG,FBXO3,NUDT5,HNRNPA2B1,OAZ3,MRPS18B,IGF1R |
| 1.908e-04 | -8.56 | NHERF2 (NHERF family PDZ scaffold protein 2) | protein interactions | 9351 | 174 | 71 | 19454 | 5460 |
CTNNA1,TACO1,ACOX1,PTEN,PLCB2,SLC1A1,SIAH1,PTPRQ,RAB11A,COPS7A,OTUD7B,TOMM40,RHOB,TAFAZZIN,SLCO3A1,DTL,RPS28,ARHGEF6,CD40,AKAP1,RTN4,LSM12,ADRB2,PPP2R3A,WASF3,RNF41,CFTR,GRM2,PPT1,PAK2,SLCO1A2,PRKCA,UBE2M,GIT2,SIN3A,SMAD3,HRAS,COPS2,G6PC3,DLGAP4,PRNP,KCTD10,KCTD3,COPS7B,KIF3B,NPC2,CACYBP,WWP2,CTNNB1,TMA16,COPS5,P2RY1,TST,KLHL24,NUDT5,LPAR2,KCTD17,ZBED1,CHN2,KRAS,COPS4,TUSC3,E2F4,GTF2E2,DDX39A,MAP1LC3B,ACTN4,RPL29,NHERF1,NUDT19,OTULIN |
| 1.910e-04 | -8.56 | Sm_dom_euk/arc | interpro domains | IPR001163 | 20 | 14 | 18521 | 5414 |
LSM5,SNRPG,LSM6,LSM10,SNRPD3,SNRPD1,SNRPD2,LSM4,SNRPB,LSM2,LSM3,LSM8,SNRPN,SNRPE |
| 1.921e-04 | -8.56 | RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) | protein interactions | 5929 | 276 | 105 | 19454 | 5460 |
TOP1,MIOS,CDC5L,DKC1,SMAD3,H2AZ1,RB1,H2AC4,CSNK2A1,KPNA2,H3C1,KDM4B,PAGR1,TCOF1,DISC1,SESN2,TP53,TBK1,EGR2,RPL13A,BUB3,TXN,VIRMA,PELP1,PTEN,UBE2I,CSNK2B,MECP2,SMAD2,CDC73,AKT1,SMARCA5,AR,RUNX1,NUCKS1,KDM1A,CXXC1,MBD3,HCFC2,DYRK2,CCAR2,KCTD10,NOP58,PRPF18,SIN3A,RPLP2,WDR82,KDM2A,LHX2,DPY30,MAP1S,HMGA1,TAF7,CTNNB1,RUVBL1,RBBP7,KRAS,SSRP1,PAX6,RERE,MORC2,RUVBL2,SMARCB1,MTA2,DHX38,MAX,CSNK1E,ELF1,SAP30,SOX2,TUBA1A,TUBB,RBBP4,POLR2B,PPP5C,ELK3,RAN,IRF2,PHKB,BST2,RPL37A,PRMT5,DCAF4,BRCA1,H1-1,CUL3,CREBBP,MYC,HNF1B,RBM15B,CPSF2,SMARCE1,PRPF31,KANSL3,STAU1,TGIF2LX,SAP18,FOS,EP300,PSMA3,PPARG,KLF3,CTBP1,MED23,KLC2 |
| 1.926e-04 | -8.55 | regulation of interleukin-21 production | biological process | GO:0032665 | 7 | 7 | 18204 | 5365 |
MIR215,MIR192,MIR222,MIR21,MIR221,IL6,FOXP1 |
| 1.926e-04 | -8.55 | regulation of calcidiol 1-monooxygenase activity | biological process | GO:0060558 | 7 | 7 | 18204 | 5365 |
IL1B,IFNG,CYP27B1,GFI1,VDR,NFKB1,TNF |
| 1.930e-04 | -8.55 | CCNO (cyclin O) | protein interactions | 10309 | 25 | 16 | 19454 | 5460 |
SATB1,MNAT1,CDK5,PCNA,APPBP2,RPA2,VAV2,CDK1,CDKN1B,CKS2,HSPB1,CKS1B,SUFU,CIAO3,CDKN1A,CDK7 |
| 1.930e-04 | -8.55 | HEBP1 (heme binding protein 1) | protein interactions | 50865 | 25 | 16 | 19454 | 5460 |
SNX3,LGALS3,UBE2L3,PPIA,S100A6,BOLA3,TMSB4X,HSPA8,AKR1B1,GNPAT,GSTO1,ISOC1,CRABP2,GAMT,PYURF,COTL1 |
| 1.935e-04 | -8.55 | regulation of protein catabolic process | biological process | GO:0042176 | 361 | 138 | 18204 | 5365 |
TSPAN15,PCSK9,PSMC5,USP14,MAD2L1,PSMD10,DEDD,SUMO1,RGMA,GSK3A,HGS,EGLN2,CDK5RAP3,NDFIP1,PSME1,RAD23B,SOX9,AZIN2,MYLIP,CSNK2A1,SNX12,TSPAN5,AZIN1,VIP,MSN,TRIB1,PSMD14,PIAS1,PSMC3,PACSIN3,ATRAID,IL10,ZFAND2A,SMAD3,XPO1,TNF,DDRGK1,SVIP,PSMC4,GPX1,PHB1,LAMP3,SEC22B,RHBDD3,TAF9,TNFAIP3,TRIM32,IL1B,NOP53,HFE,VPS28,AKT1,STUB1,USP13,PSMC1,GCLC,PITHD1,CLU,SMAD4,CCAR2,PSMD3,SNX33,OAZ2,RNF128,GABARAP,FBXW7,FURIN,WNT10B,USP8,CAV1,NFE2L2,DET1,MAD2L2,USP5,TIMP1,FBXO22,AGAP2,HSP90AB1,FAF1,CTSA,VGLL4,ODC1,TSPAN17,PSMD1,SNX3,SOCS5,CDKN1B,COP1,HECTD1,GABARAPL2,TNFRSF1B,OPHN1,ATG7,NQO1,CD81,SGTA,MTM1,PSEN1,CSNK1A1,PSME2,RGP1,DNAJB2,IDE,SNRNP70,AQP11,UFL1,DESI1,IFNG,UBE2K,STX5,MDM2,DTL,CST3,CAMLG,UBB,NUPR1,OAZ1,CDC20,FZR1,FHIT,IER3,OAZ3,CSNK1E,ZER1,RCHY1,USP38,ROCK1,TIMP3,SUMO2,BAG2,ASB11,LDLR,TIMP4,TNFSF12,RNF41,HSP90AA1,EEF1A1,SOCS4 |
| 1.935e-04 | -8.55 | HECW2 (HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2) | protein interactions | 57520 | 319 | 119 | 19454 | 5460 |
ZC3H14,PSMB3,ACTL6A,ETF1,LARP4B,PSMB7,NCOA5,TMEM174,UPF3B,EMG1,RTL9,ZFP64,ARRDC3,PAFAH1B2,UBE2D3,GRB10,RBM15B,CPSF2,CHTOP,LMNB1,RPS6KA4,RCL1,LSM14B,GTF2F2,PRMT5,HECW1,SPINDOC,PRDX2,SNRPB2,CBX5,POLR2B,MORC4,CRTC2,DCUN1D5,LSM14A,MORC2,RNASE4,PCNA,LDLRAD4,RAD21,TMED7,MAP1S,ZNF207,PPIB,AVL9,DRG1,DDT,CDC23,SPHK2,HNRNPD,SP2,HMG20A,SRSF10,PIP5K1A,EIF3J,NTPCR,SLC35E1,ZCCHC17,WWP1,LMNA,TRIM3,KIN,LITAF,PRRG1,LYNX1,TAF5L,CSK,CDC16,DNAJC8,CFL1,LACRT,MECP2,ALKBH5,ANAPC4,EIF2AK2,PNP,SMAD5,SMURF1,SCML2,TECR,UBE2L3,CSTF3,CDC20,TP53,GGCT,WBP11,CHAMP1,DMAP1,CBX3,DHRS7B,ILDR1,MEIOB,NOSIP,PC,RING1,LRP3,CTNNBL1,ARF4,FAM133B,GMPPA,ERV3-1,MPG,CSNK2A1,RPL24,SMCHD1,TUBG1,OSBPL8,KPNA1,HACD3,METAP1,MRPS9,ACSL4,PSMB1,PWP2,GATAD1,MIOS,FZR1,RBM42,SLC25A17 |
| 1.936e-04 | -8.55 | TSPAN15 (tetraspanin 15) | protein interactions | 23555 | 273 | 104 | 19454 | 5460 |
MSMO1,EXTL2,SLC25A17,DERL2,ARL6IP5,SLC39A10,FITM2,ADGRE2,NUS1,ESYT1,TMEM70,CCR6,FAR2,EI24,LPCAT3,MAN1A2,LPAR2,DDR1,TSPAN3,SURF4,TMEM205,ALG11,TMEM126A,VKORC1L1,CLRN2,CD47,SC5D,MGST3,SCAMP2,REEP6,DNAJC19,BICD2,HMOX2,CNNM4,RETSAT,RGS2,TSPAN5,LPAR1,SLC7A1,CERS2,RTN4,NDUFC2,RETREG2,PIGW,LEMD3,TM9SF1,GOLGA5,P2RY12,ADIPOR1,FUT8,RABL3,SYNGR2,TLCD4,SLC38A3,XPO5,OCIAD2,CD63,SLC20A1,TMEM164,FAM241B,FAM241A,EMC6,SYNJ2BP,KRAS,PGAP4,EFNB1,TMEM87A,GNA11,GPAA1,LGR4,CYB5R1,LPAR6,ALG5,CHP1,SYNE4,REEP4,LRRC8A,GPR89A,FZD4,RETREG3,SLC30A7,MOG,PIGK,S1PR4,ATP1A3,LRRC8C,TM9SF4,GPR17,KDSR,ENTPD4,CERS6,SLC37A4,TACR3,ZDHHC17,CMTM6,SLC35F2,TACR1,ATP2C1,HSDL1,PIP4P2,RDH12,SIGMAR1,YIPF5,SLC19A2 |
| 1.936e-04 | -8.55 | HSPA1L (heat shock protein family A (Hsp70) member 1 like) | protein interactions | 3305 | 273 | 104 | 19454 | 5460 |
CDC5L,MAPRE2,FZR1,DCUN1D1,CAND1,EEF1AKMT3,HACD3,HRAS,DNAJC7,SHC1,TUBG1,VASH1,GAPDH,COPS5,HDAC6,DNAJB2,NFKB1,FKBP8,MEPCE,CCIN,NEDD8,RPL3,TFCP2,H2AX,MAP1LC3B,TP53,UBL4A,CDC20,UBASH3B,PTEN,STUB1,DNAJC19,NCKIPSD,ST13,DNAJC8,PPP1CC,DNAJC5,ATP5F1A,CNTNAP1,RETSAT,HSPA5,CLU,METTL22,PIK3R2,TNFAIP1,ARFIP1,DLAT,DVL2,BAP1,INPPL1,UBE2M,HEXIM1,FGFR1,CFTR,NEK2,UQCRC1,DENND2D,CCND1,HSP90AB1,CCAR2,PHB1,CBL,AGR2,XPO1,STOML2,RUVBL1,KGD4,SLC25A23,DNAJB4,RUVBL2,HNRNPA2B1,CHMP4C,GDI2,METTL21A,TRAF2,ESR2,TAB1,DYNLL1,LRRC28,AP2M1,UBE2S,CYB5R3,ILK,DNAJB6,HSP90AA1,BRCA1,MLF2,BAG3,BTF3,RAB11A,CUL2,CUL3,NDUFB7,MYC,STAU1,NDUFS2,PSMA3,HSPA8,DNAJC3,SLC25A3,EDEM3,SHMT1,H1-5,TOMM22 |
| 1.942e-04 | -8.55 | TSPAN31 (tetraspanin 31) | protein interactions | 6302 | 49 | 26 | 19454 | 5460 |
MTCH2,FAM162A,ATP5PB,NRM,ALG11,TSPAN15,RETREG2,HSDL1,SLC35F2,B4GALT7,RIGI,RHOBTB3,CD81,FXYD6,FITM2,CD63,PTPN1,LAPTM4A,VAMP3,GPR89A,GJA1,RETREG3,XPO5,SPCS1,LGALS3,DNAJC1 |
| 1.942e-04 | -8.55 | EDNRA (endothelin receptor type A) | protein interactions | 1909 | 49 | 26 | 19454 | 5460 |
MCL1,XPO5,SLC30A7,MPDU1,VKORC1L1,SRC,GNAI2,MGST3,SLC25A4,REEP4,COPS5,TMBIM6,SMPD2,ATP1A3,ENDOD1,TMEM87A,GNA11,RUSF1,PXMP2,ARL5B,KDELR2,SYNGR2,TMEM126A,MTX2,CAV2,KDELR1 |
| 1.942e-04 | -8.55 | RAP1GAP (RAP1 GTPase activating protein) | protein interactions | 5909 | 49 | 26 | 19454 | 5460 |
VPS26C,APEX1,ZNF330,RAP1B,FBXW11,YWHAZ,YWHAB,VPS26A,SFN,YWHAG,FBXO7,XPO1,YWHAH,SKAP2,DYNC1I1,CNR1,RPA3,UBE3A,EZH2,CDK1,GNAI3,GNAZ,RAP1A,TP53,MAP1LC3B,CFTR |
| 1.946e-04 | -8.54 | SLCO4A1 (solute carrier organic anion transporter family member 4A1) | protein interactions | 28231 | 44 | 24 | 19454 | 5460 |
HAX1,KLK5,RHOB,RHOG,TAFAZZIN,LAMP3,RAB5C,RAB2A,LGALS3,RHOJ,RHOH,ARMC6,RAB35,HRAS,ACACA,RAB4A,GP9,CDC42,DDX39A,TOP3B,CCR4,STX7,KRAS,LRRN4CL |
| 1.946e-04 | -8.54 | TMEM203 (transmembrane protein 203) | protein interactions | 94107 | 44 | 24 | 19454 | 5460 |
STOM,MANBAL,TMEM31,LMNA,TMEM14B,PDZK1IP1,TIMMDC1,FAM174A,SCN3B,TOP3B,CREB3,MMD,TMEM60,ATP6AP2,RNASEK,LY6G6C,ELOVL4,SSMEM1,TMX2,CD3G,RMDN3,HSD17B11,MFSD5,RETREG3 |
| 1.950e-04 | -8.54 | KRT6B (keratin 6B) | protein interactions | 3854 | 108 | 48 | 19454 | 5460 |
MEPCE,UBE2A,TRIM37,TRIM26,IGF1R,UBE3A,EWSR1,RNF8,SMARCB1,TFCP2,EZH2,TP53,B3GNT2,CAND1,EFNA3,CBL,DDRGK1,HNRNPA1,COPS5,HDAC6,NDC80,OIP5,KDM1A,UFL1,INPPL1,DDX39B,WTAP,TFIP11,HEXIM1,METTL14,CFTR,NUP62,USP38,VIRMA,SNRNP40,NDN,TRIM54,UBASH3B,RPS20,ALB,AP2M1,EIF4A3,RNF208,UBE2H,YWHAZ,PDE4B,CUL3,MYC |
| 1.951e-04 | -8.54 | CKAP5 (cytoskeleton associated protein 5) | protein interactions | 9793 | 270 | 103 | 19454 | 5460 |
ACTL6A,MFAP1,SDC2,PALS2,HSPA8,AKAP1,RAB5A,STAU1,BTF3,BAG3,MYC,LDHB,OSGEP,DNAJB6,RIT1,YWHAZ,CYP1A1,BRCA1,PHF21A,TRMT6,DLST,PELO,ESR2,SOX2,ANAPC13,B3GNT2,MARCKSL1,CCR1,MOB3C,CYB5B,PLS3,TUBB4B,PNMA2,ZC3H7A,EFNB1,BAG2,EIF2D,KRAS,SEMA4C,YWHAG,YWHAH,DDRGK1,IFI16,NDC80,MED4,AHSA1,EED,SPINT2,KLHL7,FBXO32,EGLN3,WIF1,HSP90AB1,SNRPD3,SUMO2,SNRNP27,ATG16L1,TPT1,UBE2M,HAUS2,RPA2,CDK1,METTL14,CLK1,BAP1,RPA3,SIRT7,HSPA5,KDM1A,NF2,RPS17,MAPRE1,UBE2H,ZNHIT3,CHCHD4,MSN,CCNF,METAP2,TUBA1B,CTTN,DYRK1A,VIRMA,NDN,LDHA,KBTBD4,COMTD1,HSPA13,HAPSTR1,RAB1A,MEPCE,RIGI,CTNNBL1,SEM1,HNRNPK,TGFBR2,CD274,CDK9,CDC5L,SLAIN2,FZR1,RPS16,RPL35A,TOP1 |
| 1.954e-04 | -8.54 | Glutathione conjugation | REACTOME pathways | R-HSA-156590 | 38 | 23 | 10285 | 3229 |
GSTO1,MGST2,GSTO2,GSTP1,GSTA1,GSTK1,GCLC,GSTM4,CNDP2,GSTM5,ESD,CHAC2,GGT7,AKR1A1,GSTA4,GSTA2,GSTT1,HPGDS,GGCT,MGST3,GSTM2,GSTM3,GSTT2B |
| 1.956e-04 | -8.54 | anaphase-promoting complex-dependent catabolic process | biological process | GO:0031145 | 22 | 15 | 18204 | 5365 |
FZR1,CDC20,ANAPC15,UBE2S,ECRG4,ANAPC16,ANAPC4,ANAPC2,FBXO31,CDC23,CDC16,ANAPC11,ANAPC13,CDC26,CUL3 |
| 1.957e-04 | -8.54 | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 36 | 21 | 16828 | 4835 |
SF3B1,EWSR1,SMAD4,NFE2L2,STK11,SS18,IDH1,HRAS,KRAS,PTEN,EZH2,TERT,PIK3CA,JAK2,ETV6,AKT1,FBXW7,RB1,KIT,CTNNB1,TP53 |
| 1.958e-04 | -8.54 | STAM (signal transducing adaptor molecule) | protein interactions | 8027 | 145 | 61 | 19454 | 5460 |
TIMM8A,FURIN,HGS,ZRANB2,VPS33A,STMN2,PIR,BAG2,JAK1,TMT1A,AHCYL1,CPLX1,RPS27A,TOLLIP,TRIM63,PSMA5,EMC8,LAMP3,WWP2,LAMP2,USP15,YWHAB,GJA1,IGBP1,TSG101,RAP1B,CAV1,WIF1,STX6,SNX1,BET1,STAMBP,EMC9,FGFR1,ARRDC3,SQSTM1,HSPA8,PML,PPM1G,CXCR4,RHOU,USP8,PPP1CC,SEC13,CSK,SERPINH1,DNAJB6,EPHA2,NTRK3,S100A11,SNTA1,TRAF7,CYRIB,OPTN,CCNF,STUB1,CD79B,ESR2,JAK2,RHOJ,TRIM54 |
| 1.964e-04 | -8.54 | regulation of interleukin-6 production | biological process | GO:0032675 | 175 | 74 | 18204 | 5365 |
TLR1,CD200R1,TLR7,TYROBP,RIGI,TICAM1,SPHK2,MIR204,MAVS,MIR105-1,TIRAP,MIR708,MIR195,MIR338,UCN,CD36,TLR9,IFIH1,XBP1,GHRL,SETD4,SOCS5,TLR2,MIR206,MYD88,TRAF6,AFAP1L2,LILRA2,TLR8,MIR149,AIF1,CAPN2,MIR657,MIR146A,LILRB4,IL17F,TNF,CD47,MIR101-1,TLR3,CX3CL1,IL1A,IL10,IFNG,MIR144,TNFAIP3,NMBR,IL6,HYAL2,CSK,CLEC7A,TMEM106A,SELENOK,SYK,HMGB1,PTPN22,HSPD1,BCL10,MIR132,FOXP3,DHX9,IL1B,MIR98,PTPN11,TLR6,MIR140,CD200,AGER,MIR361,PYCARD,TLR4,IL1RAP,LEP,SELENOS |
| 1.975e-04 | -8.53 | DBT (dihydrolipoamide branched chain transacylase E2) | protein interactions | 1629 | 183 | 74 | 19454 | 5460 |
PTEN,TACO1,MRPL53,TNFRSF1B,CCDC90B,DLST,ESR2,USP16,GRPEL2,RPGRIP1L,TUFM,ISCA2,RALB,AUH,MTG2,MYC,PMPCA,CDO1,MCAT,PPTC7,MYO6,GFM1,RHOU,EXD2,NF2,RND2,IDH3B,ATG16L1,HECTD1,MTRES1,KLF3,ACAA2,PPT1,FAHD1,GATD3,SSBP1,AIFM1,COX4I1,RBM5,IFIT2,SURF6,RHOH,HDAC6,GRSF1,MTRF1,DDX1,DCAF11,MED4,MRPS26,PPM1K,MRPL18,RHOG,SNRNP70,HINT2,PRDM4,EMC2,MRPS11,COX8A,HSD17B10,TRIP4,MRPS18C,FASTKD5,RIGI,DYNC1I1,HUWE1,KGD4,RBCK1,MECR,METTL15,MRPL11,GFM2,ACOT13,NDUFS6,PDHA1 |
| 1.975e-04 | -8.53 | DEK (DEK proto-oncogene) | protein interactions | 7913 | 183 | 74 | 19454 | 5460 |
H3C1,DHX16,TRIM63,THRAP3,PHF1,MEPCE,RAD21,PPP1R12A,UBE3A,CDK8,CBX3,EZH2,RBPJ,SMARCB1,NUPR1,FURIN,RAF1,ACTR1A,CAND1,TMED9,DHX15,CD274,FBXO32,ALYREF,EED,SNRNP70,POU5F1,ARMC8,BRD3,USP15,BAZ1B,COPS5,CSNK2A1,XPO1,DDRGK1,SRSF2,UFL1,UBE2K,STAU1,FBXW7,RPA3,PYM1,SF3B1,TXNL1,EP300,RPA2,LMNA,METTL14,HEXIM1,ACTL6A,CDC42,POLR1D,TAX1BP1,APEX1,DEK,RPL10,TUBA1B,ZNF330,RPL37A,CSNK2B,GANAB,MACROH2A1,SPOP,FTSJ3,NRP1,AP2A1,H1-1,UBE2H,SMARCA5,CREBBP,MYC,SFN,H2BC9,USP14 |
| 1.979e-04 | -8.53 | RCN2 (reticulocalbin 2) | protein interactions | 5955 | 264 | 101 | 19454 | 5460 |
DRG2,HSPB1,IFI16,DDRGK1,XPO1,DNAJB9,NDUFS8,ELK1,UQCRH,EGLN3,PHB1,FBXO32,IFIT2,BRD9,CYB5A,CORO1C,CHMP4C,NDUFS6,HDAC11,PDHA1,MOB3C,RAF1,B3GNT2,EEF2,GABARAPL1,DNAJC25,ASPM,VDAC1,EMC8,DNAJB4,ILK,SP1,CUL3,PYCR1,BTF3,ATP5F1B,ESR2,CBX5,SEC61B,ARMCX3,NDUFA5,FKBP10,KCND3,UFL1,ASB3,TMEM106B,EP300,AKAP1,POR,EID1,BRD3,TESK1,FAM20C,DNAJC1,FZR1,PTPN1,NDUFS3,CBX3,SLC25A24,TP53,CLEC2B,DNAJC30,PRDX4,RIGI,SFXN1,TFPT,EMC2,IGF1R,RC3H2,DNAJC10,SPOP,UBE2H,DNAJC19,CALU,NDUFB10,AKT1,NPTX1,TUFM,HMOX2,ATP5F1A,PRKCE,VIRMA,DYRK1A,FAM210A,CCNF,UQCRC2,GRM2,FGFR1,HAUS2,CYC1,UBE2M,GTF2H4,GABARAPL2,CFTR,GABRA1,FBXW7,HSPA5,SLC2A3,BAP1,RNF113A,SQSTM1 |
| 1.984e-04 | -8.53 | TUBA4A (tubulin alpha 4a) | protein interactions | 7277 | 501 | 177 | 19454 | 5460 |
G3BP1,CDK20,RPS27A,OSTM1,TRIP4,NDUFA4,EZH2,CHMP4C,AQP3,RAF1,B3GNT2,TXNRD1,FAF2,CD1A,CACYBP,OPRL1,CBFB,FOLR1,PHB1,MAP1LC3A,BCL2L1,P2RY10,UCHL3,NPTN,SLC15A1,FBXL4,UNC45A,NCALD,PRKAB1,DAAM1,STXBP1,TUBB,SIAH1,MAD2L2,CD79B,ENO2,BRCA1,PFDN2,KLK5,PFDN4,ILK,PFDN6,CUL3,CUL2,SAMHD1,CD80,TCP11L2,TTC4,FBXO25,LTA,IGF1R,MLLT11,STARD13,CCT5,EEF1A1,DDX39A,MAP1LC3B,TM4SF1,DCUN1D1,MAPRE2,PRNP,AIFM1,TES,C2CD2,MOV10,HDAC6,CRYZ,RPA3,WNT7A,CST11,PRKCB,RTN4,CTDSP1,HAUS2,PSMC4,RPS14,ATG16L1,ARHGAP1,COPE,VIRMA,GNAI2,CEP97,ENO1,CHRM4,TUBA1B,SENP5,TMEM108,RACGAP1,VDAC1,RUVBL1,RPL28,RAB8B,PRPS1,CCT8,RUVBL2,TUBB4B,NUDCD3,SOX2,TUBA1A,NOB1,TCP1,SUMO2,RAMP3,CCT7,SSR2,S100A8,MAGED2,FKBP4,CBL,HSPB1,PFDN5,YWHAG,XPO1,STAU1,DDX39B,HSPA8,GPHN,THBS3,DNAL4,PIH1D1,CSNK1A1,TOMM22,SYK,INSYN2A,TSHR,POLR2B,PHF12,CCT2,ICAM1,MYC,TBCE,NXPH3,BTF3,PSMD1,BRINP3,NEDD8,HNRNPK,MEPCE,PDRG1,ABCE1,TFCP2,SERPINB11,KBTBD4,TP53,INSIG2,CHRM3,MGARP,CAND1,SLAIN2,CDC5L,BRINP2,TUBG1,CD81,COPS5,ST8SIA4,CRYL1,HSPA5,BAP1,RBM23,HCFC2,TMEM263,PGK1,RPA2,TCP11L1,FGFR1,HEXIM1,TRIM36,HCST,GABRA1,CFTR,CDC20,SRC,KLK6,B4GALT1,RC3H2,UBE2H,SLC25A1 |
| 1.993e-04 | -8.52 | purine ribonucleoside triphosphate biosynthetic process | biological process | GO:0009206 | 85 | 41 | 18204 | 5365 |
NDUFC2,ATP5PF,NDUFS6,ATP5F1A,NDUFB10,NME1,SDHC,NDUFAB1,NDUFA1,NDUFS8,NDUFA2,NDUFB8,NDUFA5,NDUFB7,ATP5MC3,ATP5MK,ATP5PO,COX11,NDUFA12,NME2,LIPA,SDHB,ATP5MG,NDUFS2,ATP5PB,ATP6V1A,UQCC3,DNAJC30,NDUFB4,STOML2,ATP5PD,NDUFS3,ATP5F1E,NUDT2,NDUFV2,ATP5F1B,NME4,NDUFB5,NDUFB6,ATP5MC1,ATP5F1D |
| 1.993e-04 | -8.52 | oligodendrocyte differentiation | biological process | GO:0048709 | 85 | 41 | 18204 | 5365 |
CSK,ID4,PTPRZ1,NCSTN,NKX6-2,CDKN2C,CTNNB1,FA2H,CNP,GPR17,EIF2B3,CNTNAP1,PLP1,EIF2B2,PTEN,PAX6,LPAR1,GPM6B,CERS6,MECP2,ASPA,DLX1,BOK,KCNJ10,MYRF,HDAC11,MOBP,TPPP,NTRK2,EIF2B5,DUSP10,B4GALT6,WASF3,SRSF1,CLU,CDK5,CNTN1,RHEB,SOX9,MIOS,TLR2 |
| 1.994e-04 | -8.52 | ARL1 (ADP ribosylation factor like GTPase 1) | protein interactions | 400 | 186 | 75 | 19454 | 5460 |
ACTB,MAD2L2,VIRMA,NECTIN2,CCNF,RRAS2,CHCHD4,YWHAZ,GCC1,LAMTOR1,UBE2H,FAM219A,SLC38A1,NTRK3,CUL3,MYC,SLC30A5,GORASP2,OTUD7B,STAU1,YKT6,HSCB,GOSR1,UFL1,G3BP2,COIL,RPA3,MME,BET1L,ARFIP1,MAVS,GOLGA5,STOM,GRM2,SLC12A2,RPA2,LEMD3,ARCN1,TOMM22,RABL3,DUSP22,CFTR,ANKRD46,ELK1,TMPO,SLC38A2,PTPN1,SRPRA,STX5,ESYT1,CDK5RAP3,POR,YWHAB,PTPN5,ASB1,DNAJB2,ATG9A,DDRGK1,YWHAH,HSPE1,KRAS,GTF3C3,PSEN1,EFNB1,ACTR2,STIM1,TFRC,OTULIN,ARFGEF1,RAF1,ARFGAP1,PLEKHA8,LBR,CTDSP2,TUBA1A |
| 2.001e-04 | -8.52 | negative regulation of interleukin-1 production | biological process | GO:0032692 | 52 | 28 | 18204 | 5365 |
CPTP,RAD21,IGF1,MIR708,IL10,PML,ACP5,MIR204,MIR181C,CX3CL1,MIR101-1,CX3CR1,MIR920,GSTP1,SERPINB1,TNFAIP3,MIR195,MIR877,MIR142,MIR488,PYDC2,GHRL,MIR181D,IL1R2,NLRP3,MIR132,MIR98,LILRB4 |
| 2.007e-04 | -8.51 | RAB11B (RAB11B, member RAS oncogene family) | protein interactions | 9230 | 148 | 62 | 19454 | 5460 |
KRAS,TRIM37,RAB3B,VAMP8,RIGI,RAB1A,VAMP2,GDI2,STX12,GNAI3,H2AX,GABARAPL1,HADH,RAB1B,RHOH,RBM42,WDR44,HRAS,IFIT2,UBE2N,RHOG,AGR2,RAB5C,PGAM1,YWHAG,PHB2,STX7,NT5C3A,ABCC2,LYG2,BAP1,RPA3,EXD2,RTN4,SLC35F2,RAB5A,RPA2,FGFR1,SSR1,SCLT1,HEXIM1,ELOVL1,DUSP14,CDC42,RND2,RAB6A,RHOJ,LGALS3,ATP6AP2,USP5,ESR2,VAMP3,OPTN,ARF1,ACOX1,SCAMP2,TRIM27,ETNK2,SEC61B,YWHAZ,SH3BP5L,RAB11A |
| 2.007e-04 | -8.51 | EXOSC9 (exosome component 9) | protein interactions | 5393 | 148 | 62 | 19454 | 5460 |
RBM7,UBE2H,EXOSC1,MAP3K21,CUL3,MYC,APEX1,SMURF1,UBE2I,RSRC1,PSMA6,ZNF330,PELO,PSPC1,PIH1D1,METTL14,PALS2,RPA2,SLC35E1,ATP6V1G1,ZDHHC17,EEF1G,UFL1,C1D,EXOSC4,PML,BAP1,LUM,RPA3,PRIM2,DDX39B,DRG1,MPHOSPH6,SNRNP70,ZCCHC9,EIF3D,DDRGK1,DIS3L,MPG,CSNK2A1,COPS5,HP,SUMO2,FZR1,RPS16,CAND1,EIF4E2,SRP14,EXOSC3,EZH2,EXOSC8,DDX39A,SOX2,E2F4,TP53,RAF1,PSMD12,PSMA5,KRAS,H3C1,PSMA2,RPL31 |
| 2.011e-04 | -8.51 | MCUR1 (mitochondrial calcium uniporter regulator 1) | protein interactions | 63933 | 189 | 76 | 19454 | 5460 |
POLDIP2,MRPS7,GRPEL1,PHB2,NDUFS2,NME4,PDHB,DLAT,HADHA,GFM1,PDSS2,NDUFA5,MRPS34,ATP5PO,MRPL12,PRDX3,TIMMDC1,PTAR1,COQ8B,NDUFAF4,CPT2,ATP5F1B,PTPMT1,ACAT1,MRPS28,CCDC90B,DLST,TACO1,MRPL53,MRPS25,NOA1,MRPS16,PYCR2,PYCR1,NDUFB10,FLOT1,FASTKD5,MRPS17,ETFA,ATP5F1D,HSPE1,PDE12,MRPS33,MRPS18B,ATP5PF,THNSL1,HSPD1,PREPL,NDUFA12,NDUFS3,NDUFS6,PDHA1,NUDT19,BCS1L,PPIF,FAF2,ETFB,MRPL47,NDUFA2,HSDL2,ATP5PB,MRPS23,ATP5PD,NDUFS8,SPPL3,COX4I1,PHB1,MRPS9,MRPS26,NDUFV2,MMUT,STOML2,COX5A,MRPS35,GRSF1,CLPX |
| 2.020e-04 | -8.51 | positive regulation of interferon-beta production | biological process | GO:0032728 | 40 | 23 | 18204 | 5365 |
POLR3F,OAS1,IRF7,TLR7,RIGI,TICAM1,TLR3,POLR3B,MAVS,TLR8,TOMM70,ISG15,IRF3,PTPN11,HSP90AA1,TBK1,FLOT1,TLR4,TLR9,IFIH1,TLR2,IRF1,DHX9 |
| 2.022e-04 | -8.51 | secretory granule lumen | cellular component | GO:0034774 | 321 | 123 | 19108 | 5553 |
COTL1,CCT2,VEGFA,SDCBP,XRCC5,TF,EEF2,RETN,NME2,HSP90AB1,PSMC3,COMMD9,ACTR1B,CAND1,HUWE1,CHI3L1,PSMD1,CTSA,VWF,RARRES2,CXCL1,PPIA,CCT8,ROCK1,PSMA2,PSMD3,S100A8,ALB,CTSD,PSMA5,HMGB1,NPC2,EEF1A1,HP,TUBB4B,TUBB,DSN1,PRDX6,FAF2,MAGED2,FAM3C,HEXB,IGF1,SERPINB1,PLAC8,DNASE1L1,AGA,PSMB7,CAMP,OLA1,MIF,SCG3,JUP,FGR,TOLLIP,GHRL,GTPBP2,TEX264,SERPINI1,TMSB4X,CLU,ACTN4,LYZ,GGH,CAB39,FTL,PYGB,PSMB1,SRGN,ARMC8,VEGFC,RNASET2,CDC37L1,CYB5R3,TRAPPC1,HSP90AA1,IDH1,SELENOP,GSTP1,ATG7,CSTB,VTI1B,PSMD6,TTR,CYRIB,PSMD12,TGFB2,HSPA8,NFKB1,SERPINA1,ILF2,CSNK2B,DBH,PNP,SRP14,SPTAN1,DNAJC3,PAFAH1B2,PROS1,B2M,GDI2,SERPINA3,PSMD14,PLG,TIMP1,NEU1,CTSC,GCA,PSMD7,TGFB3,TIMP3,S100A11,PADI2,HEBP2,PCYOX1L,RAB27A,FABP5,PRDX4,TOR4A,PGAM1,PYCARD,ACTR2,SLPI |
| 2.026e-04 | -8.50 | SLC25A10 (solute carrier family 25 member 10) | protein interactions | 1468 | 192 | 77 | 19454 | 5460 |
NRP1,UBE2H,ILK,LAMTOR1,LACRT,RAB2A,MYC,CUL3,TECR,ESR2,DYNLL1,CPT2,FBXO22,MRPS28,SMU1,BAD,PIH1D1,GRM2,ZNF326,GABRA1,CRAT,CFTR,CDK7,MRPL12,BET1,COIL,UFL1,ADRB2,HSPA8,PRKCB,AKAP1,RNF113A,EP300,RTN4,SQSTM1,RHOU,PEX3,ESYT1,AGR2,HDAC6,MRPL9,NR2F6,LAMP3,MMUT,SCGB1D1,MAP3K14,DDRGK1,MOV10,MDFI,MAPK4,ELK1,TMPO,PCSK9,MRPL50,LDLR,COQ8A,PHB1,HDHD5,FBXO32,EZH2,PDHA1,FAF2,SOX2,MAP1LC3B,TUBA1A,ASPM,RAF1,B3GNT2,TP53,SOCS2,FLOT1,DCP2,RUVBL1,HSPD1,MAP1B,NDUFA4,BCKDK |
| 2.027e-04 | -8.50 | vesicle lumen | cellular component | GO:0031983 | 327 | 125 | 19108 | 5553 |
SRGN,PSMB1,GGH,FTL,PYGB,CAB39,CLU,ACTN4,TEX264,SERPINI1,TMSB4X,LYZ,TOLLIP,GTPBP2,GHRL,OLA1,CAMP,MIF,AGA,PSMB7,JUP,FGR,SCG3,MAGED2,FAM3C,FAF2,PLAC8,DNASE1L1,HEXB,SERPINB1,IGF1,PRDX6,TUBB,DSN1,HMGB1,CTSD,PSMA5,NPC2,EEF1A1,ALB,HP,TUBB4B,S100A8,PSMD3,ROCK1,CCT8,PSMA2,RARRES2,VWF,PPIA,CXCL1,CTSA,PSMD1,FASLG,CAND1,CHI3L1,HUWE1,PSMC3,HSP90AB1,COMMD9,ACTR1B,RETN,TF,EEF2,NME2,VEGFA,XRCC5,SDCBP,CCT2,COTL1,SLPI,PYCARD,ACTR2,PRDX4,TOR4A,PGAM1,RAB27A,FABP5,PCYOX1L,S100A11,TIMP3,TGFB3,PADI2,HEBP2,CTSC,GCA,TIMP1,NEU1,PSMD7,GDI2,SERPINA3,B2M,PLG,PSMD14,PNP,DBH,PROS1,PAFAH1B2,DNAJC3,SRP14,SPTAN1,SERPINA1,CSNK2B,ILF2,TGFB2,HSPA8,NFKB1,CYRIB,PSMD12,BACE1,TTR,GSTP1,ATG7,SELENOP,PSMD6,VTI1B,CSTB,HSP90AA1,IDH1,TRAPPC1,CDC37L1,RNASET2,CYB5R3,ARMC8,VEGFC |
| 2.030e-04 | -8.50 | regulation of protein serine/threonine kinase activity | biological process | GO:0071900 | 267 | 106 | 18204 | 5365 |
PPARG,CDKN3,NTRK3,MIR218-1,PAQR3,CAMK1,CCNA2,CCNB1,CDKN1B,PKIG,RGCC,MIR711,CDKN2D,EZH2,CAV3,TAB1,IL34,MAP3K12,SPRY1,HEXIM1,TLR4,CDK5R1,PIK3CG,THY1,MIR26B,PSRC1,FGFR1,TPD52L1,INPP5K,PTPN1,GHR,SRC,PDCD4,ERP29,FERMT2,DUSP19,MIR15A,MIR34A,DIPK2A,CCNY,TCIM,IFNG,CCL19,DIRAS1,CCND1,CDK12,DIRAS2,TRIB1,SLC8A1,MIR20A,CCNH,KIT,CCNF,TRAF6,GADD45A,MAP2K1,PIH1D1,HGS,DVL2,CDK5RAP3,TESK1,RB1,DIRAS3,DEFB114,PTEN,TSG101,PSMD10,CDKN1A,LRP6,MACROH2A1,FGF1,PKIB,CAB39,TLR6,BCCIP,ADRB2,STK38,DUSP10,PKIA,PYCARD,HRAS,PROX1,PTPN22,FGF16,HEXIM2,CD40,RGS2,IL1B,AKT1,RALB,TRAF2,GSTP1,HYAL2,GH1,CDKN2C,DUSP1,CCND3,RPS3,CCNI,SERTAD1,PDCD10,ADIPOQ,TNF,ACTB,MAP3K11,MIR24-1 |
| 2.039e-04 | -8.50 | cullin-RING ubiquitin ligase complex | cellular component | GO:0031461 | 186 | 77 | 19108 | 5553 |
SPSB1,DTL,SPOP,ANAPC11,CCNF,CDC26,ANAPC16,FEM1C,MAD2L2,SKP1,FEM1B,KLHL12,DCAF12L2,FBXO9,FBXO7,CACYBP,DET1,FBXO25,FBXO31,KLHL24,CDC23,KLHL9,DCAF16,SPOPL,FZR1,UBE2S,ANAPC2,CKS1B,DCAF4L2,CAND1,ANAPC4,FBXO44,CUL2,RNF7,SPSB3,ANAPC13,FBXO32,DCAF11,FBXL4,FBXL3,CDC20,KLHL3,COP1,FBXL19,CDKN1B,FBXW7,FBXW4,APPBP2,CUL3,KCTD17,CKS2,WDR77,DCAF8L2,FEM1A,ENC1,FBXO3,FBXL7,FBXW11,TNFAIP1,ZER1,ELOC,KCTD10,KBTBD6,FBXO42,FBXL14,ANAPC15,TMEM183A,KLHL25,CRBN,CDC16,DCAF5,KLHL15,PCMTD1,KLHL7,KLHL22,TRIM21,DCAF4 |
| 2.039e-04 | -8.50 | USO1 (USO1 vesicle transport factor) | protein interactions | 8615 | 195 | 78 | 19454 | 5460 |
PML,RPA3,BAP1,EP300,BET1L,RAB9A,HSPA8,GOSR1,YKT6,KDM1A,BET1,GOSR2,ACTL6A,SETD9,NUP62,STXBP1,SNRNP27,SEC22A,EMC9,HSP90B1,FGFR1,RPA2,PIH1D1,UBE2M,CTTN,LMBR1L,SCN2B,PHF21A,GSK3A,CSNK2B,GANAB,TENT5C,COPE,VIRMA,ESR2,MORF4L1,RAB11A,GPR17,BRCA1,CYP1A1,SPOP,DNAJB6,POLR1B,RIT1,NTRK3,SCFD1,RAB1A,HAPSTR1,EFNB1,TRIM37,HUWE1,KRAS,SAR1B,PHYKPL,TP53,COMTD1,RAF1,MAP1LC3B,GABPB1,PDHA1,MOB3C,CCR1,EFNA3,RPL9,STX5,GJA1,PRNP,WIF1,CDC5L,CAV1,POLE3,MDM2,ZNF593,PTP4A3,STX6,ERLIN1,CTNNB1,COPS5 |
| 2.040e-04 | -8.50 | mRNA destabilization | biological process | GO:0061157 | 178 | 75 | 18204 | 5365 |
EXOSC8,MIR130B,MIR98,MIR211,MIR140,MIR23A,MIR26B,MIR190B,MIR340,MIR495,YTHDF1,CNOT8,MOV10,MIR885,MIR1-1,MIR191,MIR145,HNRNPD,ROCK1,AGO1,CNOT6L,MIR9-1,MIR142,MIR135B,PDE12,CNOT2,MIR223,MIR34B,MIR106B,ROCK2,MIR192,MIR185,MIR24-1,MIRLET7C,MIR130A,MIR212,MIRLET7B,MIR149,MIR519D,MIR146A,CNOT6,METTL14,MIR96,MIR30B,MIR497,MIR100,MIR320A,MIR20A,MIR193A,DCP2,MIR214,MIR625,MIR181D,ALKBH5,FXR2,MIR342,MIR206,MIR106A,MIR373,MIR16-1,MIR491,MIR195,YTHDF2,MIR210,EXOSC3,MIR424,MIR137,MIR200C,CNOT7,MIR708,RC3H2,MIR181C,MIR125A,MIR204,MIR423 |
| 2.043e-04 | -8.50 | ribonucleotide biosynthetic process | biological process | GO:0009260 | 195 | 81 | 18204 | 5365 |
GUK1,ATP5PF,NDUFC2,TECR,NDUFS6,PDHA1,SDHC,UMPS,NDUFA2,PAPSS2,ACAT1,NDUFB8,AK5,SDHB,LIPA,ELOVL4,ATP5PO,AK2,ELOVL7,HACD1,ELOVL6,UCK1,DCAKD,NDUFB4,ATP6V1A,ADCY3,ADSS2,NPPC,NDUFS3,CMPK1,ACACA,ELOVL1,AK3,DCK,ATP5F1E,GUCY1B1,NME4,ADCY2,ATP5MC1,ATP5F1D,NDUFB5,ACSS2,DLAT,NDUFAB1,ATP5F1A,NDUFB10,PPAT,NME1,NDUFA1,NDUFS8,UCK2,UPRT,ATP5MC3,NDUFA5,NDUFB7,PDHB,NME2,ATP5MK,COX11,NDUFA12,ATP5MG,PPT1,GMPS,HACD2,ADK,NDUFS2,MMUT,UCKL1,ACSL4,DNAJC30,STOML2,ATP5PB,UQCC3,ELOVL3,SLC25A1,ATP5PD,NUDT2,NDUFV2,ATP5F1B,NPR2,NDUFB6 |
| 2.050e-04 | -8.49 | postsynapse | cellular component | GO:0098794 | 646 | 229 | 19108 | 5553 |
RPL12,PCDH17,CPLX2,KCND3,MEF2C,LRRC4B,NPTN,HCRT,LRFN3,INSYN2B,P2RY1,LRRTM3,GABBR1,PSD2,DGCR8,DISC1,TNIK,KCTD16,RPL7,DRP2,PICK1,CAMK2N1,HPCA,CNTN2,AKT1,SPTBN1,ADORA1,SIGMAR1,ARF4,EIF3E,ADD2,CTTNBP2,DLG4,SPOCK1,DAG1,KCNB1,SNAP25,USP8,TRAPPC4,EIF4A3,HTR2A,BAALC,NCDN,GLRA1,LIN7B,GABRA2,DLG1,GABRB2,ATAD1,CHRNA7,GPM6A,EPHA4,WASF3,NGDN,AGER,DROSHA,RGS7BP,NSG1,RPL10A,GLRB,RPS14,KCND2,CDC42,KCNA2,KCTD12,SEMA4C,HNRNPD,LHFPL4,PSEN1,LIN7C,CNTN1,PPP1CC,ATP1A2,NETO1,TIAM1,PPP3CA,CALY,IGSF21,SNX14,ABHD6,PICALM,ADD1,CPEB1,PAK6,RAB5A,MTMR2,GRIA2,CLSTN3,BMPR2,RHEB,GSK3A,MT3,DLG3,GRIA1,INPP4A,FXYD6,CHRNB2,SLC6A1,LPAR1,IGF2BP1,PTEN,GLRA2,ABHD17A,GABRB3,OPHN1,SIPA1L1,GABRA1,CTNND1,ARF6,SLITRK1,HNRNPH2,ACTB,DAPK1,MOB4,MAP1B,ATP1A1,PHB2,RPL8,KCNH1,DNM2,RPL6,FABP5,PLCB1,DRD1,SLC1A1,KCNJ2,IGSF11,CDK5,DLGAP4,PRRT1,CRYAB,SRC,HOMER1,CHRM5,JAK2,SH2D5,SSPN,CHMP2B,ZC4H2,GPHN,FLRT3,AP2M1,STX12,HSPA8,PPFIA2,CHRM4,ARF1,CHRM1,RAB3A,LRRC4,STXBP1,TMUB1,SLC6A3,KPNA1,ZDHHC15,KIF3B,SYN3,INA,ATP6AP2,CTNNB1,SNTA1,NTRK2,GRIK1,IQSEC1,GRM1,CAP2,CRKL,PRNP,SLC29A1,CUL3,CTTN,MKLN1,INSYN2A,OPRK1,ASIC2,NETO2,INSYN1,TMEM108,RPLP0,CBLN1,EPS8,MECP2,GHRL,NRP1,HOMER3,GNG3,EIF4E,RPS13,TPPP,FCGR2B,NEFL,KCNA3,ELAVL4,HTR5A,RAB11A,RPS3,PCDHB13,EIF4EBP2,SLC6A6,PKP4,KCNC1,CDK5R1,SYNDIG1,GRID1,PAK2,PDLIM4,FAM81A,SLC6A11,SLC8A1,KCNMA1,NLGN2,NLGN1,SLC6A4,RTN4,CHRM3,CPSF2,CACNG3,AP2S1,CPLX1,GABRG2,RAB4A,LRRTM1,C1QC,PDE4B,LRRTM2,AP2A1,C9orf72,SLC4A10,RNF10 |
| 2.054e-04 | -8.49 | POLR1B (RNA polymerase I subunit B) | protein interactions | 84172 | 151 | 63 | 19454 | 5460 |
IKBKB,KPNA1,NFKB1,IFI16,HDAC6,ATG7,ZNF207,CAND1,GFOD1,POLR2I,EGLN3,RPL9,RPRD1A,POLR2L,MAD2L1BP,POLR2C,POLR2G,POLR2D,NUPR1,RPAP2,TAF1D,KRAS,DNAAF10,KPNA2,PDRG1,MCM6,AKT2,TCOF1,RPAP3,ABCE1,TEX19,RC3H2,ATG3,PFDN2,RPS5,POLR1B,RIT1,PFDN6,MYC,RRN3,LDB1,ACTB,POLR2B,ESR2,APEX1,NFKBIB,POLR3B,POLR2F,POLR3H,RPA2,RPRD1B,GIT2,PIH1D1,CCND1,FAXC,POLR1D,CDK7,STAU1,TRIM52,POLR1H,SKP1,RPA3,TRIM10 |
| 2.054e-04 | -8.49 | CPT1A (carnitine palmitoyltransferase 1A) | protein interactions | 1374 | 151 | 63 | 19454 | 5460 |
ENO1,LMBR1L,UQCRC2,VDAC2,OPTN,SLC1A1,TAX1BP1,LDHA,ATP5F1B,VIRMA,GABRG2,HMOX2,TOMM40,ATP1A3,SLC39A9,HADHA,RNF113A,PHB2,NPTN,EMC1,HSPA5,ATG16L1,ATP6V1C1,KLRD1,CDC42,UQCRC1,PPT1,GP9,CYC1,PIH1D1,PHB1,CORO1C,HNRNPL,CD1A,ERLIN1,DUOXA2,ELK1,NDUFS8,EMC4,MOV10,HDAC6,AGR2,SLC2A1,TUBG1,NDUFA4,MAP1B,HSPD1,EMC2,HUWE1,TP53,NDUFA2,MTCH2,B3GNT2,FBP1,RAF1,LGR4,YIPF3,TMEM59,PDHA1,AQP3,HDAC11,RPN1,PLD3 |
| 2.054e-04 | -8.49 | COLGALT1 (collagen beta(1-O)galactosyltransferase 1) | protein interactions | 79709 | 151 | 63 | 19454 | 5460 |
OS9,CCT7,TMPO,TCP1,C1QTNF1,DNAJB9,PHB1,SSBP1,POU5F1,FKBP4,DAG1,GAPDH,XPO1,EMC4,DPP4,HNRNPDL,HNRNPK,DNAJC30,CSE1L,TOLLIP,RUVBL1,CCT8,RAB1A,HSPD1,PSMC3,NUPR1,PDHA1,TFRC,HSPA13,UBR7,PPP2R1A,TRAF2,E2F4,PSMD6,ACTB,ADRM1,ATP5F1B,CTSB,SEC61B,CDC7,GANAB,PAPSS2,CALU,UBE2H,DNAJC10,ZNHIT3,GMPS,PSMA4,HNRNPC,CUL3,MYC,HSPA5,FBXW7,TMEM106B,PML,DNAJC3,RPA3,PAK2,LMNA,RPA2,UBLCP1,CFTR,CNPY3 |
| 2.055e-04 | -8.49 | TGIF1 (TGFB induced factor homeobox 1) | protein interactions | 7050 | 32 | 19 | 19454 | 5460 |
JUN,COMMD3,EEF1A1,SMAD1,AR,MDFI,SMAD2,RIT1,STK16,MED31,CTBP1,SMAD3,SIN3A,PML,LRIF1,ESR2,MKKS,KRAS,HMGB1 |
| 2.055e-04 | -8.49 | HTR1A (5-hydroxytryptamine receptor 1A) | protein interactions | 3350 | 32 | 19 | 19454 | 5460 |
TRIM21,CORO1C,HTR1A,CREB1,GPR26,TGFBR2,SPPL3,PPP1CC,EEF1A1,JUN,SEC13,WDR77,GNAI3,RPLP0,HNRNPH3,HNRNPD,PSMD7,FGFR1,EIF3G |
| 2.055e-04 | -8.49 | KIAA2013 (KIAA2013) | protein interactions | 90231 | 111 | 49 | 19454 | 5460 |
SFTPC,SKA3,GPR34,CRELD1,TOP3B,COMTD1,CLEC2B,TMEM60,ADRA1A,TSPAN17,BSCL2,LPAR2,PICK1,KPNA1,RNF139,TMEM199,RAB32,TMBIM6,CCR6,SRPRA,STARD3NL,GPR35,P2RY12,RPA2,KLRD1,TMEM106A,LPAR1,CLEC12B,HSPA5,CLDND1,TSPAN15,RPA3,TMEM185A,VIPR1,ATP1B3,ZMPSTE24,NLRP3,HNRNPAB,ZNF687,SCN3B,CSGALNACT2,H2BC9,RALA,ATP6AP2,ESR2,S1PR4,LMBR1L,ST8SIA5,AMIGO1 |
| 2.055e-04 | -8.49 | PCK1 (phosphoenolpyruvate carboxykinase 1) | protein interactions | 5105 | 111 | 49 | 19454 | 5460 |
RPL4,SKP1,PSMC1,DNAJC3,EP300,SQSTM1,GPHN,PSMB7,ZNF501,RPLP0,PCK2,NUP62,PSMC4,CNP,ZDHHC16,RPL10L,ACTB,PSMD6,PRDX2,LDHA,RPS3,UBE2I,ZMYM2,PSMC5,PSMD14,CCT2,SMPD2,AKT1,SRPRB,PSMA2,PSMA5,FBXO25,PSMD12,SOCS2,HSPD1,MRPS18B,INSIG2,CCT5,FAF2,TSC22D3,TCP1,CIB3,PSMB4,PSMB1,MAGED2,ARL2BP,RPL23,TRIM8,ELOC |
| 2.055e-04 | -8.49 | Ube2i (ubiquitin-conjugating enzyme E2I) | protein interactions | 22196 | 111 | 49 | 19454 | 5460 |
PRSS23,VPS4B,LMNA,RPRD1B,CTBP1,RALYL,UBA52,SUMO1,TMEM209,NHP2,HMGB1,YTHDF1,NUP50,CLK1,ATP5MK,MECP2,FAS,ZMAT3,SEC13,TNFAIP3,SRPK2,PRKRA,RAN,CCNF,NME1,LLPH,GLE1,EXOSC8,NUP37,NUP153,STRBP,TRMT1L,RNF20,RUVBL1,KPNA2,NUP42,THRAP3,NUP107,DHX9,SRSF8,RBM3,SLC2A1,HMGA1,NUP35,PEG10,SUMO2,THOC1,MIF,ELSPBP1 |
| 2.056e-04 | -8.49 | regulation of IRE1-mediated unfolded protein response | biological process | GO:1903894 | 14 | 11 | 18204 | 5365 |
COPS5,DNAJB9,PTPN1,BFAR,AGR2,HSPA5,BAK1,UFL1,BAX,DDRGK1,TMEM33 |
| 2.060e-04 | -8.49 | WDFY1 (WD repeat and FYVE domain containing 1) | protein interactions | 57590 | 62 | 31 | 19454 | 5460 |
VPS28,EGR1,STX7,VAMP8,RPA3,TLR3,VAMP2,RPA2,NTPCR,EHD1,TXNL4A,MYLIP,STBD1,GPR37,SNX2,CGAS,SNX1,AP2M1,SCAMP2,VAMP3,FAM219A,TMEM123,BMERB1,OSGEP,GNG2,RAB11A,SEC13,NUDT1,CIAO3,LAMP2,ATG9A |
| 2.060e-04 | -8.49 | CLMN (calmin) | protein interactions | 79789 | 62 | 31 | 19454 | 5460 |
CTNNA1,PTPN1,SEC61B,HSD17B11,AP2M1,ACTB,PRNP,HNRNPL,DNAJC1,VIRMA,ESR2,TMPO,UBB,SFN,CTNNB1,PPP1CC,YWHAG,YWHAH,TMT1A,ZYX,RPA3,RAB9A,DERL1,RTN4,RAB5A,MTDH,SYVN1,HSCB,SEC62,SSR1,STIM1 |
| 2.060e-04 | -8.49 | KIF18B (kinesin family member 18B) | protein interactions | 146909 | 62 | 31 | 19454 | 5460 |
NUP50,P4HA2,MRFAP1L1,RPA3,PTGES3,RIGI,KPNA2,STAU1,ASF1A,H3C1,PPP1CB,IMP3,NUP62,PNMA2,RPA2,NELL2,ZNF330,FBLN5,S100A6,CCDC71,MAD2L2,APEX1,SUMO2,FZR1,CUL3,UBXN6,MOV10,MYC,MAPRE1,ANAPC4,H2AC4 |
| 2.060e-04 | -8.49 | DRAP1 (DR1 associated protein 1) | protein interactions | 10589 | 62 | 31 | 19454 | 5460 |
SNRNP70,TAF9,TNFRSF14,LMO2,PIK3R3,MORF4L1,BTF3,GTF2E1,IRF1,FBXO7,DRAP1,PLEKHF2,MED17,SUMO3,POLE3,SRPK2,RPL9,GTF2B,FEZ1,GTF2F1,SDCBP,SMARCB1,RAD23B,LNX2,NFYB,NUCKS1,FOXD3,CDKN2C,PICK1,DR1,MRPS11 |
| 2.061e-04 | -8.49 | POLR2M (RNA polymerase II subunit M) | protein interactions | 81488 | 128 | 55 | 19454 | 5460 |
HSPA8,INPPL1,FTL,POLR1H,POLR1D,MED30,PIH1D1,RPRD1B,WWP1,FEM1A,POLR3B,GPN2,POLR3H,POLR2F,UQCRQ,POLR2B,DAPK1,RPGRIP1L,MED17,MYC,MED22,RPL7A,PFDN2,MCAT,POLR1B,MED10,BRCA1,CPNE2,RPAP3,FAM168A,PDRG1,COA1,SSNA1,DNAAF10,RPAP2,SPRR1B,THAP1,MED9,POLR2D,KLHL26,POLR2G,POLR2C,DXO,CEBPG,RPRD1A,POLR2L,PRNP,POLR2I,XPO1,SIVA1,WWP2,MED4,CBL,MED21,MED27 |
| 2.061e-04 | -8.49 | SH3BP4 (SH3 domain binding protein 4) | protein interactions | 23677 | 128 | 55 | 19454 | 5460 |
CAV1,HNRNPL,ARF6,TCP1,RHOH,GJA1,RAC2,TES,DNM2,RAB35,EIF4E2,YWHAB,RHOG,PDCD1,FKBP4,YWHAH,YWHAG,SRSF12,KRAS,PSMA1,EFNB1,TESK2,RND3,TFRC,TOP3B,SH3BP4,VIRMA,ESR2,ATP6AP2,RHOJ,NTRK3,TBC1D25,RHOB,YWHAZ,MYO6,DNAJC5,MYC,SFN,FAM110B,STX7,HSPA5,TXNL1,FAM53C,THBS3,TTC1,RHOU,DVL2,AGAP1,CSNK1A1,RND2,SIPA1L1,GKAP1,CDC42,CFTR,TOR1AIP2 |
| 2.064e-04 | -8.49 | NANOG (Nanog homeobox) | protein interactions | 79923 | 240 | 93 | 19454 | 5460 |
RB1CC1,HMGA1,DPY30,MRPS35,MRPL9,DNTTIP1,EIF3D,NOP58,CCAR2,PEG10,TRMT61A,SIN3A,HDHD5,MTA2,SSBP3,RAF1,SOX2,TUBA1A,ZNF609,GTF3C3,PDE6A,HNRNPDL,ARGLU1,FBXO11,TRIM21,BAG2,RTCB,CIRBP,CUL3,CFAP20,MLF2,SNRPB,PCMTD1,TUBB,TRMT6,VRTN,RPE,SOX21,PPP2R3A,XRCC5,HSPA8,EP300,PCGF2,EMG1,CCDC86,SMAD4,CRBN,AKAP8L,RBM17,CSNK2A1,ELOC,KLHL22,ALYREF,NDUFS3,PCMTD2,ILF2,MRPL49,PHC1,OTX2,RAD23B,MTA3,TOR3A,IPO8,ING1,HUWE1,BACH1,RAB13,SPOP,CDC73,ANAPC4,NAA50,SUGP1,CFL2,TIA1,TXN,PRKCE,TENT2,GANAB,ING2,TRIM24,PPP2R5E,CDAN1,LEMD3,WTAP,TXNL4A,GTF3C4,EDF1,ELP3,MBD3,NBN,HNRNPH2,TNFAIP1,SQSTM1 |
| 2.067e-04 | -8.48 | myelination | biological process | GO:0042552 | 128 | 57 | 18204 | 5365 |
NTRK2,DICER1,EGR2,B4GALT6,EIF2B5,CD9,SOD1,ORMDL1,AMIGO1,CNTN1,ZNF24,TLR2,NAB1,NCSTN,MAP2K1,ACER3,ILK,HEXB,EIF2B2,PLP1,PTEN,MYRF,TPPP,CXCR4,MOBP,GPC1,PMP22,HRAS,MTMR2,GAL3ST1,AKT2,CLU,ORMDL3,MARVELD1,LARGE1,AKT1,DAG1,KLK6,SLC25A46,MIOS,ID4,NKX6-2,HEXA,MPZ,GNPAT,FA2H,DEGS1,HYCC1,CNTNAP1,GALC,LPAR1,GPM6B,NAB2,ASPA,FIG4,KCNJ10,RAF1 |
| 2.074e-04 | -8.48 | cellular response to hypoxia | biological process | GO:0071456 | 139 | 61 | 18204 | 5365 |
MIR146A,CCNA2,PPARG,SLC29A1,PGK1,AQP3,NDP,HP1BP3,RGCC,CBL,SUV39H1,ERO1A,CDKN1B,MIR20A,TERC,CPEB1,MIR214,MIR17,MSTN,MIR448,BAD,BNIP3L,ADO,PRKCE,EGLN2,TERT,VEGFA,MIR210,PMAIP1,GAD2,NFE2L2,FOS,NGB,MIR140,ATF4,NKX3-1,CLCA1,PHB2,NDNF,AIFM1,KCND2,NOP53,SRC,STUB1,FAM162A,LMNA,HILPDA,MGARP,MIEF1,EGLN3,MT3,ACAA2,KCNMB1,MIR34A,MIR126,SFRP1,MYC,TP53,MDM2,STC1,MIR106B |
| 2.085e-04 | -8.48 | NUMB (NUMB endocytic adaptor protein) | protein interactions | 8650 | 213 | 84 | 19454 | 5460 |
RND2,CDC42,BET1,LNX2,PRKCA,FRS3,SPRYD4,RAB5A,RAB9A,HSPA8,PRKCB,RPA3,DVL2,RHOU,STX7,PSENEN,DNAJC5,ANAPC15,FBXO7,SFN,RAB11A,RAB2A,CSK,NTRK3,AP2A1,RHOB,YWHAZ,LAMTOR1,PTEN,SLC1A1,AP2M1,SMAP2,CTNNA1,ESR2,APEX1,ATP6AP2,PRKCE,RHOJ,SPCS1,SIAH1,TULP3,MAP1LC3B,SOX2,TP53,RAF1,RND3,ITGB5,SPSB3,RAB4A,CAPZA2,IGF1R,RPL3,HSPD1,FLOT1,RAB3B,L1CAM,EPHA4,KRAS,YWHAH,LAMP3,YWHAG,XPO1,RAB5C,ZCCHC10,LAMP2,ATG9A,YWHAB,STAMBPL1,PDZK1IP1,RHOG,RAC2,IGBP1,GJA1,RAB35,HRAS,CAV1,MDM2,DIRAS3,LMAN1,EGLN3,STX6,RHOH,ARF6,HNRNPL |
| 2.085e-04 | -8.48 | SCN3B (sodium voltage-gated channel beta subunit 3) | protein interactions | 55800 | 213 | 84 | 19454 | 5460 |
TMEM30A,MUL1,FAM241B,CENPL,TMEM42,FXYD6,TMBIM6,FAM20B,PMP22,TMEM208,FAR2,SLC38A7,DHRS7,ST6GALNAC3,MDM2,STX6,EXTL2,VTI1B,SLC38A3,ANKRD46,MFSD5,XXYLT1,GLT8D1,TMEM14A,RNF8,TMEM14B,VAMP2,YIPF4,UBIAD1,NRM,AGPAT5,INSIG2,TP53,LEPROTL1,TUSC3,TMED7,FKBP8,SACM1L,TMEM60,USP30,ADIPOQ,ERG28,YIF1A,BCAP29,STX8,RUSF1,TMEM87A,TMEM50B,SFXN1,SLC7A11,SLC38A1,FIS1,SLC35E4,ENTPD4,RETSAT,TMED4,SLC25A31,MGST3,TVP23B,CDIPT,VAMP3,FAM3C,SMCO4,VAPB,TMEM115,JUP,TIMM23,MED23,USE1,FGFR1,CCDC167,SEC22A,PLP2,CTXN3,VAMP1,FAM234A,CDSN,ABCC5,SLC7A1,TMEM243,DERL1,TMEM203,HSDL1,ORMDL1 |
| 2.085e-04 | -8.48 | DDX46 (DEAD-box helicase 46) | protein interactions | 9879 | 213 | 84 | 19454 | 5460 |
METTL14,LMNA,RPA2,ACACA,CSNK1A1,SUMO1,SF3A1,PSMC4,SNRNP27,AGO1,UFL1,PSENEN,PML,SIRT7,RPA3,BAP1,EP300,RNF113A,TCEA1,RTN4,SF3B1,HSPA8,PRKCB,TXNIP,UBE2H,RIT1,HSP90AA1,PEA15,CUL3,DNAJC8,AR,SNRPB,ANAPC15,PSMD1,FBXO22,SPCS1,IFI6,NDN,VIRMA,SRPK2,TCEAL7,SNRPB2,MAD2L1,EZH1,SF3B6,SF3B4,SNRPD2,SNRPD1,SMNDC1,NUPR1,TMEM14B,SNRPE,OTX2,SF3B5,TP53,RAF1,H2AJ,CD2BP2,ERLEC1,HUWE1,KRAS,PSMB10,CCAR1,HSPD1,SRSF7,EMC2,ABCE1,DDX23,UQCR11,ANKRD50,RBM17,DDRGK1,SNRPA1,SNRPD3,RPL35A,DHX15,HSP90AB1,CDC5L,PPIA,TMPO,RCHY1,SRSF1,SIN3A,FOLR1 |
| 2.087e-04 | -8.47 | MYL6 (myosin light chain 6) | protein interactions | 4637 | 225 | 88 | 19454 | 5460 |
DES,ESR2,ATP5F1B,SNRNP40,LGALS3,SETD7,LAMTOR1,FAS,RHOB,BTF3,MYC,ACO2,CUL3,ARL6,UFL1,DDX39B,PIH1D1,PPT1,DET1,WDR77,HSP90AB1,FHIP1B,DNAJB9,USP46,FOLR1,CBL,AGR2,DDRGK1,CTNNB1,DCAF4L2,WWP2,AHCYL1,RAD21,PSMA1,TNF,KRAS,TRIM37,EWSR1,EZH2,CHMP4C,ISG15,RAF1,RANBP1,VIRMA,MOB4,TRIM24,OPTN,CCNF,FAM210A,UBE2H,AR,PPP1CC,RAB2A,PIAS1,HSPA5,FBXW7,RNF113A,BAP1,UBE2M,HEXIM1,CYC1,JUP,METTL14,CDC42,CDK7,CFTR,ATG16L1,MYL12B,MYL12A,CDK9,FZR1,TPPP2,PRNP,TES,AIFM1,SNRNP70,HDAC6,DPP4,MEPCE,REXO2,TOLLIP,HSD17B10,NUPR1,RNF181,TFCP2,DISC1,FBP1,KBTBD4 |
| 2.087e-04 | -8.47 | CLUAP1 (clusterin associated protein 1) | protein interactions | 23059 | 225 | 88 | 19454 | 5460 |
PSME2,WDR6,HSP90AB1,CACYBP,INA,IFT25,PTDSS1,HSPB1,HAX1,BAG2,MYO1B,EFNB1,SLC25A5,KIF2A,ASPM,IFT22,SMNDC1,IFT172,SEC61B,PELO,GNG12,CBX5,RPL35,TOMM40,ALDH1L1,DNAJB6,SCFD1,SLC7A11,HSP90AA1,BAX,H2AZ2,HSPA8,ATP5MK,LCA5,SEC62,TIMM13,PGRMC1,SLC25A3,FDFT1,VAPB,HCLS1,TIMM8B,SRP14,SRPRA,SDHB,VTI1B,ISYNA1,DHRS7,KXD1,AKAP8L,UBXN10,TTC8,SNAP23,IFT52,MRFAP1,STX18,SLC25A11,SLC25A10,PTGES3,SRPRB,HUWE1,TIMM8A,TMEM205,TP53,CDK4,SNAP29,PREB,TMEM165,IFT57,MRPS28,PSMC5,MID1IP1,CINP,TECR,MGST3,NCAPG2,CFL2,CALU,CLU,HSPA5,CNP,KDELR2,SLC35E1,NDUFAB1,SEC22B,SLC35F6,ACACA,SSR1 |
| 2.088e-04 | -8.47 | MRPL44 (mitochondrial ribosomal protein L44) | protein interactions | 65080 | 222 | 87 | 19454 | 5460 |
MRPL52,RPL17,MEPCE,FASTKD5,METTL15,AURKAIP1,MRPL47,MRPL11,MRPL49,MRPL51,GFM2,PRR3,COX4I1,SSBP1,MRPL24,MALSU1,MRPL50,GRSF1,TMEM70,SNRNP70,SHC1,CHCHD1,MTDH,SPCS2,GFM1,MME,RPA3,MRPL20,MRPL41,SLC25A51,MRPL17,RBMS2,MRPL10,MPV17,MTRES1,RPA2,CCNF,MRPL53,RPL13A,EIF4H,TUFM,CEP70,DNAJC19,SRSF7,COX8A,HINT2,HSPD1,UTP25,MRPS17,H1-6,PDHA1,NFKBIL1,GATD3,PHB1,RMND1,SRSF10,TRA2A,MRPL9,HNRNPA1,SYNJ2BP,MTRF1,MRPS26,IKBKB,MRPL18,RHOG,EXD2,NGRN,HSCB,PTN,TMEM177,TIMM29,MRPL12,RPL27A,MRPS18A,MRPL13,MTG1,TACO1,RPL19,RPL10,MRPL23,PMPCA,CUL3,CFAP20,MYC,AUH,MTG2,ILK |
| 2.088e-04 | -8.47 | NUP205 (nucleoporin 205) | protein interactions | 23165 | 222 | 87 | 19454 | 5460 |
CUL3,RAB11A,MYC,RIT1,LMNB1,RHOB,ARHGAP19,RAN,LMBR1L,S1PR4,ESR2,APEX1,SSH3,RND2,BET1,TOMM22,NUP62,FDFT1,RAB5A,AKAP1,HSPA8,FBXW4,COIL,DUSP26,PHB2,DDRGK1,HNRNPA1,VPS26A,IFI16,PEX3,KRT8,EED,COX14,NUP35,EGLN3,RHOH,EIF2S1,LGR4,NUDCD3,ISG15,NUP153,TUBA1A,RANBP1,RAF1,CHMP4C,EZH2,RPS24,KRAS,G3BP1,MAPRE1,XPOT,BICD2,TADA3,UBE2I,PTPMT1,ENO1,ZNF330,CCNF,DUSP10,VIRMA,RHOJ,CDK7,CDC42,ACACA,STOM,RPA2,RAB9A,VIPR1,SIRT7,PML,RPA3,TOMM20,MOV10,DPP4,STYK1,SLC2A1,RAC2,RCHY1,ILVBL,CDK9,AURKAIP1,COMTD1,NUPR1,SELENOF,CDK8,DNAJC30,NUP107 |
| 2.103e-04 | -8.47 | PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) | protein interactions | 9061 | 78 | 37 | 19454 | 5460 |
MSN,PAPSS2,PSME2,WDCP,UBA3,DHX15,IDE,FERMT2,PPP5C,PRKCE,TRIM29,DYNC1I2,RPL35A,ALKBH5,KPNA1,XPOT,NCK1,PPP1R16A,YAF2,MAPKAPK3,RPA3,NAE1,MCRIP2,FANCG,FBXW7,TOLLIP,GNL1,NSFL1C,SNRNP27,EEF1A1,PAFAH1B1,ERRFI1,CNDP2,CAPN2,TBC1D13,TFCP2,GPX7 |
| 2.106e-04 | -8.47 | nucleoside triphosphate metabolic process | biological process | GO:0009141 | 198 | 82 | 18204 | 5365 |
PGK1,ATP5PO,SDHB,LIPA,AK5,ATP1B1,NDUFB8,ATP1A2,DTYMK,BPGM,NDUFA2,RAN,SDHC,NUDT5,ENTPD4,NDUFS6,MFN1,NDUFC2,OGDHL,GUK1,ATP5PF,NDUFB5,ATP5F1D,ATP5MC1,NME4,ATP5F1E,SAMHD1,TYMS,AK3,BAD,NDUFS3,CLPX,ATP6V1A,NDUFB4,NUDT16,DCTPP1,UCK1,GAPDH,ENTPD3,AK2,NDUFA12,COX11,ATP5MK,NME2,NDUFB7,GTPBP1,NDUFA5,ATP5MC3,ENO2,UCK2,PFKFB2,FKRP,NDUFS8,NDUFA1,LDHA,NME1,ATP5F1A,NDUFB10,NDUFAB1,PGAM1,HTR2A,ENO1,OLA1,HSPA8,PGM1,NDUFB6,IER3,NDUFV2,ATP5F1B,NUDT2,ATP5PD,RAB23,UQCC3,ATP5PB,STOML2,DNAJC30,UCP2,UCKL1,ADK,GNAI3,NDUFS2,ATP5MG |
| 2.116e-04 | -8.46 | human chr6p12.2 | chromosome location | human chr6p12.2 | 17 | 11 | 26134 | 5823 |
TMEM14A,IL17F,MIR206,TRAM2,GSTA1,MCM3,GSTA2,MIR133B,PAQR8,GSTA4,EFHC1 |
| 2.127e-04 | -8.46 | CD27 (CD27 molecule) | protein interactions | 939 | 70 | 34 | 19454 | 5460 |
SEMG2,BIRC2,ATP5IF1,DAD1,CMTM6,SLC25A51,SLC7A1,TMEM205,CD59,TRAF2,TCAF2,SLC19A2,FAM234A,ATP5PB,COQ8B,LEMD3,CRELD1,GHITM,GOLGA5,SURF4,CTNNA2,ODR4,SLC30A7,HRAS,TRAF1,ATP5F1B,FAM20B,HMOX2,FAM241A,ATP5MG,KDSR,SIVA1,ADGRE2,SLC38A1 |
| 2.134e-04 | -8.45 | EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha) | protein interactions | 1967 | 131 | 56 | 19454 | 5460 |
SMDT1,MED29,COPS5,XPO1,HNRNPA1,DDRGK1,DDX50,IFI16,HNRNPL,EIF2S1,VTI1B,EIF2B2,EIF2B5,ARL4D,MTAP,SYNCRIP,STX12,SIGLECL1,CA14,EZH2,ACTR2,BZW2,CLEC2B,COMTD1,RAF1,MEPCE,MPST,CHCHD2,EFNB1,STK11,AP2A1,EPHA2,RIT1,CD226,NTAQ1,GORASP2,CREBBP,VIRMA,ESR2,RPL10,EIF2S2,SYT2,UBE2I,PSPC1,ARF1,CCNF,TRMT6,PIP4P2,RPA2,EIF2B3,SEC62,ATG16L1,LYPLA2,ADRB2,CD40,RPA3 |
| 2.134e-04 | -8.45 | GABARAP (GABA type A receptor-associated protein) | protein interactions | 11337 | 131 | 56 | 19454 | 5460 |
CD63,GJA1,TSR2,TCP1,SNX18,PGS1,STK3,TP53INP1,ATG7,STK4,ELOC,MUL1,FKBP4,RB1CC1,NEK9,TRIM21,ATG4A,DMPK,RIGI,RETREG1,STBD1,GABARAPL1,MAP1LC3B,AZI2,TFRC,TSPAN3,OPTN,TAX1BP1,KBTBD6,SRPK2,TRIM32,CUL3,MPC1,GABRG2,PKP4,ATG101,USP14,CCT2,LMNB1,ATG3,TBC1D25,RPA3,DVL2,TEX264,HDAC5,GPHN,FLCN,SQSTM1,GABARAP,ATG4C,BNIP3L,VPS28,SEC62,GABARAPL2,RPA2,SAMM50 |
| 2.135e-04 | -8.45 | negative regulation of tumor necrosis factor superfamily cytokine production | biological process | GO:1903556 | 80 | 39 | 18204 | 5365 |
TNFAIP3,MIR195,ARG2,MIR920,GSTP1,MIR488,DEFB114,CHRNA7,IGF1,RAD21,ADIPOQ,VSIR,CX3CL1,MIR185,MIR101-1,MIR105-1,MIR204,ACP5,IL10,MIR708,MIR98,MIR149,NFKBIL1,MIR130A,DICER1,MIR140,TLR4,SELENOS,TRIM27,LILRB4,TSPO,PTPN22,GHRL,GPNMB,MIR132,CD274,FOXP3,IL4,LILRB1 |
| 2.135e-04 | -8.45 | negative regulation of NF-kappaB transcription factor activity | biological process | GO:0032088 | 80 | 39 | 18204 | 5365 |
CYP1B1,RWDD3,OTULIN,ADORA3,FOXP3,BRMS1,NLRP3,GFI1,PPP2CB,TRIM37,COMMD6,TCEAL7,PYCARD,CCDC22,MIR21,CD200,MIR140,TRIM21,UFL1,NFKBIL1,KLF4,IL10,LRRC14,RBCK1,CHP1,G3BP2,NFKBIA,PSMD10,MIR15A,DAP,TMIGD3,PYDC2,TAX1BP1,PRMT2,MIR16-1,ANXA4,FAF1,TNFAIP3,CDK5RAP3 |
| 2.135e-04 | -8.45 | ATP synthesis coupled electron transport | biological process | GO:0042773 | 80 | 39 | 18204 | 5365 |
NDUFB10,UQCR11,SDHC,NDUFAB1,NDUFA1,NDUFS8,NDUFC2,COX7B2,NDUFS6,NDUFA5,NDUFB7,COX4I1,NDUFA12,UQCRQ,SDHB,COX7A1,SDHAF2,NDUFA2,NDUFB8,COX6C,UQCC3,UQCRC2,NDUFB4,COX7B,COX5A,CYC1,UQCRH,COX4I2,COX6A2,NDUFS2,NDUFV2,TAFAZZIN,NDUFA4,COX8A,NDUFB5,NDUFB6,UQCRC1,NDUFS3,COX6B1 |
| 2.135e-04 | -8.45 | mitochondrial ATP synthesis coupled electron transport | biological process | GO:0042775 | 80 | 39 | 18204 | 5365 |
UQCRC1,NDUFS3,COX6B1,NDUFB5,NDUFB6,NDUFV2,TAFAZZIN,NDUFA4,COX8A,COX4I2,UQCRH,CYC1,COX6A2,NDUFS2,COX5A,COX7B,UQCRC2,UQCC3,NDUFB4,NDUFA2,COX6C,NDUFB8,COX7A1,SDHAF2,NDUFA12,UQCRQ,SDHB,NDUFA5,NDUFB7,COX4I1,NDUFS6,NDUFC2,COX7B2,NDUFA1,NDUFS8,NDUFB10,UQCR11,SDHC,NDUFAB1 |
| 2.157e-04 | -8.44 | MED10 (mediator complex subunit 10) | protein interactions | 84246 | 100 | 45 | 19454 | 5460 |
TRIM45,POLR2L,AIFM1,RPRD1A,POLR2I,ZNF511,H2AC14,BRD3,MED4,MED29,MED27,MED21,TRIP4,PSMD12,KDM4B,RPAP2,MED9,BIRC5,POLR2C,POLR2G,POLR2D,CDK8,POLR2F,MOB4,ZNHIT6,ESR2,UBB,POLR2B,MED17,AR,MED22,MYC,MED10,MED13L,PEBP1,FBXW7,MED11,FBXL19,MED30,TOMM22,LIAS,ATG16L1,MED31,MED23,RPRD1B |
| 2.157e-04 | -8.44 | SKIC3 (SKI3 subunit of superkiller complex) | protein interactions | 9652 | 100 | 45 | 19454 | 5460 |
CHORDC1,PFDN2,CDC73,PFDN4,PFDN6,CUL3,H2BC9,TTC33,RPL10,ESR2,DUSP10,VIRMA,DYRK1A,CCNF,IRF2,PSPC1,RPA2,HSCB,STAU1,CRYL1,G3BP2,RPA3,BAP1,SIRT7,EXOSC4,AKAP1,SKIC8,HAX1,SMAD9,DNAJC7,DRG1,PFDN5,WWP2,RPS16,SPPL3,CGAS,PHB1,EEF1AKMT3,TES,MTCH2,MGARP,PFDN1,FKBP8,ABCE1,SRSF7 |
| 2.157e-04 | -8.44 | UBE2L6 (ubiquitin conjugating enzyme E2 L6) | protein interactions | 9246 | 114 | 50 | 19454 | 5460 |
UBAC2,LMNA,DCTN3,BIRC2,HSPA8,RPL27,EEF1G,GPIHBP1,RUNX1,CFL1,RNF40,COP1,ATP1A1,YWHAZ,RPS9,SMU1,TRIM27,TRAF7,RNF122,CCNF,TAX1BP1,SIAH1,TIMM8A,ACTR1A,TRIM62,ISG15,TOPORS,GNPDA2,BAG2,UBE3A,RUVBL2,RPL3,PABPC1,RAD21,RUVBL1,RBCK1,HUWE1,KRAS,CTNNB1,SIAH2,YWHAG,WWP2,TRIM8,MUL1,RPL12,SYNCRIP,DNM2,HSP90AB1,CDK9,RNF144B |
| 2.158e-04 | -8.44 | glutamatergic synapse | cellular component | GO:0098978 | 412 | 153 | 19108 | 5553 |
EPHA4,LGI1,GPM6A,NGDN,WASF3,DLG1,ATAD1,GRM1,DROSHA,ATP2B4,SYN3,CTNNB1,PLXNC1,DAG1,LRRC4,STXBP1,DLG4,CHRM1,EIF4A3,HTR2A,USP8,KPNA1,SNAP25,NPTX1,RAP1A,FLRT3,AP2M1,PPFIA2,CTTNBP2,KCNJ11,RAP1B,ARF4,GPC4,HSPA8,PPFIA3,SRC,PLG,AKT1,LPAR2,VPS18,STK38L,HPCA,SPTBN1,ADGRL3,STAU1,CHMP2B,HOMER1,JAK2,TNIK,DISC1,FZD4,DGCR8,PSD2,KCNJ2,DLGAP4,DRP2,FLOT1,C1QL3,PHB2,LRFN3,LRRTM3,P2RY1,DRD1,GABBR1,PLCB1,YWHAH,CNR1,C1QL1,ARF6,CTNND1,CPLX2,PCDH17,RPL22,ARPC2,ACTB,PAFAH1B1,DAPK1,LRRC4B,SLITRK1,HRAS,ABHD17A,C1QL2,YWHAZ,GRM2,OPHN1,RNF10,MAP1LC3A,NAPA,KCNJ8,CPLX1,LPAR1,LRRTM2,LRRTM1,EFNB1,RTN4,IL1RAP,TNR,FXYD6,CACNG3,CBLN2,SLC4A8,GRIA1,DLG3,CPSF2,STK38,NOS1AP,GRID1,PAK2,FAM81A,NLGN1,UBE3A,CLSTN3,SLC1A2,RAB11A,TIAM1,KCNA3,ELAVL4,NETO1,CDH8,ABHD6,CALY,PPP3CA,SYT4,SLITRK2,HOMER3,NRP1,WASL,CNTNAP1,PPP1CC,EIF4E,CACNB4,PSEN1,LIN7C,KCNA2,CAMKV,MECP2,EPS8,PPP2R1A,GHRL,HNRNPD,CBLN1,NTNG2,CDH11,P2RY4,RGS7BP,CUL3,NSG1,KCND2,CTBP1,WNT7A,CDC42,NETO2,GUCY1B1 |
| 2.175e-04 | -8.43 | TMT1A (thiol methyltransferase 1A) | protein interactions | 25840 | 357 | 131 | 19454 | 5460 |
STBD1,MACO1,ETFB,FAF2,VAMP2,STIM1,RPN1,RAB6B,PLD3,CYB5B,HGS,TMEM87A,RINT1,EMC8,SEMA4C,NUP42,SAR1B,RETREG1,DDRGK1,CDK5RAP3,C2CD2L,LRRC57,CD63,GJA1,CYB5A,STX5,PGRMC1,BET1,NOTCH2,TOR1AIP2,OTULINL,SEC62,RAB6A,TMEM115,VAPB,ARCN1,FDFT1,BET1L,UFL1,VEZT,RAB11A,LMNB1,SCFD1,VMP1,FAM219A,ARF1,FAM91A1,CYB5R3,GGT7,REEP4,ATP6AP2,SNAP29,PREB,CCDC47,CENPM,LBR,UBIAD1,TFRC,FAM169A,STX8,NSDHL,TSPAN17,RAB27A,STX18,TMX3,BCAP29,SRPRB,SLC6A8,FKBP8,EI24,TMEM199,SELENOS,DHRS7,HM13,POR,SMIM12,ESYT1,AREL1,OSBPL8,AGPAT1,PTPN1,SRPRA,CAMLG,EHBP1,CDCA3,DNAJC1,LMAN1,TMPO,SLC38A2,CAV1,PSMC4,RABL3,UBA52,SEC22B,ARHGAP1,TPT1,ST7,LMNA,JUP,RPA2,GOLGA5,USE1,SSR1,STOM,SLC12A2,TMX4,PDCL,LEMD3,RPA3,MME,TEX264,MTDH,SPCS2,ARFIP1,RTN4,CERS2,YKT6,SLC7A1,TMEM209,RETSAT,KCNQ5,HMOX2,GORASP2,ARFGAP3,EPHA2,ATP1A1,VAMP3,NECTIN2,ATL1,DHRS13,SEC63 |
| 2.182e-04 | -8.43 | Transcriptional Regulation by TP53 | REACTOME pathways | R-HSA-3700989 | 367 | 147 | 10285 | 3229 |
BCL6,COX8A,LAMTOR2,PPP2CB,POLR2C,PIP4K2C,GTF2H4,PRMT5,PRELID1,AKT3,AKT1,CDK9,TOPBP1,CNOT2,LAMTOR3,MAP2K6,TAF11,PRKAG1,ERCC3,CREBBP,SSRP1,RGCC,TP53,FAS,TAF9,RPS27A,GTF2H5,COX7B,RBBP8,CNOT6L,RAD1,BRCA1,NBN,COX6C,MEAF6,MTA2,PLAGL1,PRKAB1,SESN2,TXNRD1,CNOT7,CRADD,CCNH,PTEN,RMI2,COX4I1,COX5A,E2F4,SESN3,CDK12,SETD9,RFC2,RBBP7,PRDX1,YWHAB,BIRC5,TP53I3,MDM2,DYRK2,GADD45A,TAF7,TAF10,POLR2G,SUPT4H1,BAX,COX14,GTF2F2,MDC1,UBA52,RABGGTB,TCEA1,PCBP4,YWHAH,TNRC6C,PIP4P1,TMEM219,COX20,MNAT1,MOV10,TAF2,EP300,PML,POLR2B,YWHAZ,YWHAG,AKT2,GTF2F1,RBBP4,RRAGA,POLR2I,COX11,G6PD,CDKN1A,LAMTOR1,ING2,USP2,BNIP3L,CCNB1,CDK5R1,PCNA,CSNK2A1,TP53INP1,RRAGB,RFC4,CCNA2,TFDP2,MBD3,RPA3,MAPKAPK5,RFC5,CNOT8,ING5,RFC3,SUPT5H,PMAIP1,CNOT6,TXN,JUN,SFN,CDK5,TACO1,RNF34,PRDX2,RPA2,RHEB,CSNK2B,GPX2,RMI1,FOS,DDIT4,CDKN1B,COX6B1,POLR2F,ELOC,STK11,GTF2H2,COX16,POLR2D,POLR2L,PPP2R1A,BTG2,UBB,NDUFA4,AGO1,IGFBP3,CDK1,CDK7 |
| 2.192e-04 | -8.43 | catalytic step 2 spliceosome | cellular component | GO:0071013 | 89 | 42 | 19108 | 5553 |
TFIP11,SNRPD2,WDR83,SRSF1,BUD31,SNRPA1,HNRNPA1,SLU7,ALYREF,PABPC1,LSM2,SF3B6,RBM22,SYNCRIP,PRPF19,HNRNPA2B1,CWC15,CDC5L,DHX38,SNRPB2,EIF4A3,SNRPE,SNRPG,CDC40,MAGOHB,SNRPB,SNRPD3,HNRNPF,SNRPD1,MAGOH,LSM3,PPIL3,PPWD1,SNRNP40,DDX23,HNRNPC,DDX5,SF3B1,HNRNPK,ESS2,SF3A1,SNRPN |
| 2.195e-04 | -8.42 | regulation of protein localization to nucleus | biological process | GO:1900180 | 142 | 62 | 18204 | 5365 |
PSEN1,LILRB4,UFM1,CCT5,F2,TCP1,JAK1,YWHAZ,SUFU,JUP,BAG3,CTNNA1,SESN2,HDAC3,PIK3R2,CD2AP,RBM22,RAN,PIK3R1,PKIG,SUMO1,NF2,CACNB4,CD36,TERT,CDK5RAP3,TESK1,TRIM29,MAVS,HCLS1,JAK2,SIN3A,CCT2,MEPCE,LEP,STK11,CCT8,PKIA,CREBBP,CCT7,HSP90AA1,CDK1,ANGPT1,DMAP1,AKT1,SRC,LMNA,ORMDL3,TFRC,OTUD7B,TRIM8,EFCAB7,GLUL,HYAL2,FERMT2,IFNG,CHP1,SUMO3,SMAD3,DKC1,EP300,RAB23 |
| 2.195e-04 | -8.42 | PRKACA (protein kinase cAMP-activated catalytic subunit alpha) | protein interactions | 5566 | 486 | 172 | 19454 | 5460 |
RHOJ,AANAT,FERMT2,STUB1,GSK3A,MAPRE1,STK11,EPHA2,CSK,IFNAR1,DEPDC1B,PIK3R2,PFKFB2,RHOU,RPA3,SQSTM1,ARPC2,MAVS,SLC12A2,LMNA,CCND1,RGS10,KLF1,CAV1,SLC25A12,SRP14,AIFM1,CDCA3,PKIB,CALR,PKIA,MOV10,NFKB1,TRIM63,RIGI,ADD2,PSEN1,SNAP23,CCT5,MAP1LC3B,DRD1,DYNLL1,BAD,APOBEC3G,GRIA1,AVPI1,RMDN3,CLDN3,YWHAZ,LMNB1,PPP1R17,PLN,HSP90AA1,PDE7A,CUL3,ATF1,PDE4B,HAND2,NSFL1C,STX7,EXD2,VAPB,ANXA7,PGRMC1,TMEM231,CDKN1A,RPE,AGK,NUP35,FBXO32,XPO5,HNRNPD,STOML2,DYRK1B,RASGRP3,UNC119B,HSPD1,UBE3A,AKAP14,CSNK1E,MARCKSL1,RAF1,TPD52,CACNB2,MAP3K3,SRC,DYRK1A,PPP1R1B,PPP1R10,CREB1,CALU,UBE2H,GABRB3,DNAJC5,PHKA1,PRKACB,FTSJ1,UGDH,BAP1,LCP1,FGFR1,RPA2,PPP1R8,SPTBN1,PKIG,CFTR,CDC42,SNAP25,SPPL3,CAND1,UBE2N,AKR1B1,ADD1,RAP1B,TUBG1,AKAP8L,GAPDH,CSE1L,AKAP12,GNMT,FKBP8,SLC6A8,PALM2AKAP2,GAD2,ABCE1,ARPC3,SH3GLB1,RAP1A,MTCH2,ATP5F1B,VDAC2,IRF2,FAM83B,FBXW11,CCT2,DNAJB6,FIS1,UFD1,FOS,MACIR,SLU7,AKAP1,HSPA8,GSTM2,TOMM22,KLHL3,AKIP1,RHOH,AASDHPPT,ASIC1,HNRNPL,CDK17,HSP90AB1,GYS1,TNIK,AGR2,CBL,MGMT,IFI16,DDRGK1,PPFIBP1,XPO1,VDAC1,GJB1,CCT8,PABPC1,KDELR1,STMN2,PLS3,PPIL3,TOP3B,SNAPIN |
| 2.198e-04 | -8.42 | low_malignant_potential_(borderline)_tumour | COSMIC cancer mutations | low_malignant_potential_(borderline)_tumour | 41 | 23 | 16828 | 4835 |
PIK3CA,DICER1,SRSF2,RB1,CTNNB1,IDH2,AKT1,SF3B1,HRAS,JAK1,PIK3R1,FGFR1,PTEN,BRCA1,TP53,KIT,MET,FBXW7,PPP2R1A,JAK2,SMAD4,KRAS,IDH1 |
| 2.203e-04 | -8.42 | NUFIP1 (nuclear FMR1 interacting protein 1) | protein interactions | 26747 | 134 | 57 | 19454 | 5460 |
ZNHIT6,CYRIB,GNAO1,RAB14,SNRNP40,ESR2,HPCA,PRPF31,SYP,BRCA1,ZNHIT3,CRMP1,GRIA2,NAPG,CNTN1,GPM6A,H1-5,NCALD,ATP6V1C1,RBMS2,STXBP1,GNG7,MAP2K1,MACROH2A2,NOP58,PRNP,SNAP25,CDK9,PRPF19,ZCCHC10,GNG2,XPO1,SNAP91,DDRGK1,SCAMP5,TAF9,STX1A,CDH13,RAB3A,GNA11,PPAN,RUVBL2,GPM6B,CAMKV,L1CAM,RAB3B,RUVBL1,PDE2A,SMN1,ADD2,SNCB,GPD2,VAMP2,RAB6B,GNAQ,GNAZ,CPE |
| 2.216e-04 | -8.41 | chemokine receptor binding | molecular function | GO:0042379 | 74 | 37 | 18094 | 5411 |
CX3CR1,DEFB1,CXCL1,CCL19,CXCL12,CCL1,CCL5,CXCL11,CCL17,CCL28,CXCL8,CCL8,CCL11,CXCL14,CXCL13,JAK1,CCL25,CCL23,CNIH4,XCL1,CCL20,CCL2,CCL4L1,CX3CL1,STAT1,CKLF,CCL21,CCL27,CXCL10,CCL18,CXCL9,CCL24,DEFB114,CCR2,CCL3,MSMP,CXCL3 |
| 2.217e-04 | -8.41 | MKRN1 (makorin ring finger protein 1) | protein interactions | 23608 | 163 | 67 | 19454 | 5460 |
RPL23A,RPL3,SNIP1,RPL31,PABPC1,RPS13,RPS4X,RPL17,MDC1,HUWE1,THRAP3,NUP42,APOBEC3D,MAP1LC3B,EXOSC8,PAIP2B,STRBP,TP53,RPS11,RAD23B,PRR3,SYNCRIP,CDC5L,RPS10,FZR1,PAIP1,PRNP,TRA2A,PRPF19,MOV10,KARS1,RPS2,HNRNPD,DRG1,NQO1,UBE2D1,SNRNP70,SMCHD1,SF3B1,TERT,BRIX1,UBE2D3,NOP53,CDKN1A,RBMS2,PABPC5,KCNH1,FAM161A,UBE2W,NUFIP2,RARS1,SDCBP,LARP4B,MRPL13,RPS9,EIF2AK2,RPL10,ESR2,PSMD4,RPL35,RPL26,SMARCA5,MYC,RPF2,HNRNPC,IGF2BP1,RPS26 |
| 2.217e-04 | -8.41 | UBE2E1 (ubiquitin conjugating enzyme E2 E1) | protein interactions | 7324 | 163 | 67 | 19454 | 5460 |
RNF167,TRIM21,HAPSTR1,RING1,TRIM11,UBE3A,UFM1,RNF115,TRIM37,POLL,RNF20,RNF26,PAEP,TRAF2,UBR7,ZNRF1,NFE2L2,TOPORS,RNF181,RNF8,H2AZ1,UBE2N,RNF128,TYMS,TRIM45,CAND1,MBD5,MDM2,RNF14,MARCHF5,WWP2,HDAC6,MUL1,RNF152,TRAF6,CBL,YWHAB,TRIM3,RNF34,RMND5B,RNF10,RLIM,JADE1,RNF5,USP8,RNF11,TPT1,DET1,RNF103,STUB1,RNF122,TRIM27,UBASH3B,MACROH2A1,UBE2I,TRIM29,TRIM32,CUL3,FBXO7,RNF40,TRIM23,BRCA1,MARCHF3,DTL,COP1,UBE2H,TRIB1 |
| 2.217e-04 | -8.41 | PCCB (propionyl-CoA carboxylase subunit beta) | protein interactions | 5096 | 163 | 67 | 19454 | 5460 |
AGR2,COMMD5,MOV10,WWP2,ISX,NDUFS8,MALSU1,CDK17,CORO1C,EED,ATP6V1A,HDHD3,PHB1,ARL10,UBE2N,NDUFS3,LYPLA1,KBTBD4,MTCH2,TP53,ARF4,RBBP7,HUWE1,TRIM37,POC1B,PC,ALKBH4,COP1,DCAF4,TRIM23,LACRT,TOMM40,PCCB,MYC,MTG2,MRM2,PYCR2,ESR2,ATP5F1B,SMU1,PTEN,PHF21A,VDAC2,CCNF,UQCRC2,ACACA,FAM81A,DCTN4,DHRS4,UQCRC1,DET1,CFTR,TOMM22,ATG16L1,PAFAH1B1,NDUFS2,KDM1A,STAU1,PHB2,MTDH,HADHA,LCN1,INPPL1,RPA3,AMACR,PML,NLE1 |
| 2.227e-04 | -8.41 | RELCH (RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing) | protein interactions | 57614 | 57 | 29 | 19454 | 5460 |
RAB11A,CDC37L1,ATG9A,LAMP2,RAB2A,MCM4,LAMP3,LAMTOR1,USP15,HRAS,CCNF,RHOH,DYNLL1,MTM1,STX6,FGFR1,HSP90B1,RAB4A,TFRC,MOB3C,UBAP1,RPA3,RAB9A,RAB5A,PCNA,BACH1,TTC4,STX7,MCM6 |
| 2.229e-04 | -8.41 | catalytic activity | molecular function | GO:0003824 | 5569 | 1766 | 18094 | 5411 |
CPT1B,MSMO1,TDP1,GTPBP2,OVGP1,PAOX,QRSL1,PYGM,MGST2,POLR3F,ADSS2,ERO1A,PPP2R1A,DDX42,LIPT2,ACVR1B,PPME1,GLRX,ZDHHC24,PDE6A,ST8SIA5,ILK,MRM2,DUSP19,TNNI3K,PIP4P1,ABCF1,RDH12,CYP27B1,GAL3ST4,SELENOM,KCTD11,FBXO11,PNPLA4,ST8SIA4,MYORG,IRF2BPL,B3GALT2,RAB9A,MAPK10,ACVR1C,DCTPP1,DHRS3,SETD5,GSTM3,METAP1,PLA2G12A,CYP2R1,PLG,SDR16C5,DPP10,CYP2F1,DDT,RIOX2,NDUFA1,PTPN1,GNGT2,DSTYK,HDAC6,ETF1,DRG2,APTX,STAMBP,PIGC,SRC,NUDT7,TBK1,GMPPA,NPR2,EGLN2,AZIN1,DLAT,PC,HERC3,POLR2I,GNG5,GNPTG,GAD2,GGPS1,SMUG1,SOD1,ATG16L1,GBE1,TTL,GFM2,ELP3,PDF,TCP1,TRIM63,BAP1,KLK9,ST3GAL2,UBE2D3,SPPL3,ETFBKMT,NME1,CMTR1,RNF141,RNF20,CHRAC1,CAPN2,TTLL10,RAB9B,BACE1,NGB,RRAGA,NAA30,RAB2A,CERK,AIPL1,PLCB1,TOP3B,PEDS1,DMPK,ITK,RPP14,NAT2,CSKMT,GALE,ABHD16B,NKIRAS1,RDH10,PDHB,ESD,PSMA6,UQCRC1,NANP,GMDS,TXNL1,RNF122,ACHE,GPX5,MCM3,PTDSS1,MTHFD2L,RMND5B,HENMT1,ARL15,FUT8,STK38,CDKL2,HSD17B8,DESI2,MTAP,NDUFS2,TXNRD2,PSMB5,TRIM22,CRYM,FKBP4,TUBB,SIAE,FADS2,TRIM15,CRELD1,RNF133,PPM1B,TXNRD1,TFB1M,CKB,SCPEP1,MGAT4B,UBASH3B,PSMD14,ACP6,METTL15,PPP1CB,GALNT4,UBE2N,DEGS1,PFKFB2,TUBB4B,ZDHHC15,UAP1,ACSL4,CCL5,CTSC,PPIA,ISG20L2,MARCHF3,PTRHD1,DUSP9,NDUFS3,PTGDS,DESI1,PDIA2,PDHA1,CNOT7,GNPAT,MTG1,MMUT,NDUFC2,TRIB1,GPX7,NOB1,KLK5,GSTM5,GANAB,EEF2KMT,CRAT,PLPP4,DUSP21,SLU7,TPPP,RUVBL2,GALNT17,PLPPR1,TMT1A,NDUFB6,EIF2AK2,GNAI2,NAT9,IDH2,EIF4A2,TKTL1,RAB1B,HEXB,SPTSSB,SSU72,NEK2,SRPK2,NDUFS8,KLHL9,PHKG1,CDK1,PRDM4,GLO1,MMP14,MSH6,CPT2,ATP5F1A,AUH,FTSJ1,HSPB8,DPEP3,RPN1,LDAH,OTUD6A,CLP1,UCHL3,PRSS1,PSKH1,TOP1,WEE2,CPE,CLPX,CCT8,JOSD1,RNF121,SC5D,MB21D2,CTU1,TNFAIP6,FBXL14,MPPED2,CTBP1,XPNPEP1,MED17,B4GAT1,RNF39,GLT8D1,MSRB1,ART5,CHST9,AKR1A1,CSNK2A1,RAP1A,YKT6,KIAA1191,SMARCA5,ATP5PD,ENO1,HECTD1,OXSR1,BMPR1B,ATP2B4,F9,STUB1,PRKAG1,IDH3B,TAFAZZIN,KIF1C,EXOSC8,NDUFB4,PRPS1,CTSD,TANK,AKT1,PTP4A2,RGS10,SOD3,FKBP1A,RPAP2,MMP21,UQCRC2,IPCEF1,MED27,RASL12,PIGA,RAB5A,CYP2C8,CDO1,LPCAT3,TYW3,DBT,DLG1,TSEN34,CES5A,CYB5B,ARL10,RIMKLB,MOXD1,CCR1,CSK,POLR3H,PDIA3,MMP28,PPIC,CYB5R4,NDUFA2,BRCA1,TRUB1,GZMK,PTPN5,MIF,RNF41,TOR4A,GANC,USP15,PYCR1,HM13,BMPR1A,RNF10,CCND3,EXD2,CSNK2B,SETD9,RHOU,PRKCE,VCPIP1,NAA15,PRMT5,COQ8A,BIRC2,NSDHL,RDH11,POLR2C,CNP,BRAP,PNPO,AKT2,PDE8A,CDK17,RHOBTB1,MPP1,METTL2A,NUDT1,ENDOD1,CASP12,CLK1,ISG20,CYP1A1,ATG4C,MEPCE,GGCT,POMT2,GMPPB,DNPH1,EXOSC4,LYPLA1,FUT9,COX7B,MAN1A2,PTGES,GK2,TXNDC12,RCHY1,ABHD13,MAP3K11,GSTA4,SELENOI,EDEM2,NEK7,RAD1,NQO1,MAPKAPK3,MAP2K6,CPNE1,BCS1L,ADCY2,DBH,RAB23,GPX3,MSL2,PCYOX1L,FA2H,CUL3,ALG5,GPX6,GSTK1,GNAZ,NT5DC1,LIAS,ASNSD1,ATP5F1B,JADE1,RHEB,DUSP1,DYRK1B,HACD4,APOBEC3A,NUDT12,UST,PRDX4,GTF3C4,PMM2,CYP39A1,CDK5R1,RNF113A,PDE12,RGS2,PPP4C,CHST13,DDX23,DBR1,PRKCB,FAM20B,HDAC5,CNOT6L,PPM1G,TXN,LYZL6,ASMT,PIR,TOPORS,ATP5F1E,RFC3,FHIT,CRMP1,IREB2,LYG2,RAP2C,POP7,RNASE4,OSGEP,SPTSSA,PHYKPL,UMPS,CDK6,PRMT2,TAMM41,PNPLA8,MARS1,ADGB,FKBP10,SIAH1,POLR2F,RNASEL,UBE2A,USP8,CASK,RAB14,ALDH1L1,RAB27A,CSGALNACT1,TLR1,CMBL,FXN,EDNRA,MFN1,GSTO2,NAA60,RNF182,ATP6V1G2,PELI1,ALKBH3,RNF26,MTA2,DRG1,GNAI3,HAS3,EEF2,IL1RAP,RAP1B,EIF5B,MTM1,CA12,PSEN2,FUT1,POR,SLX1A,TPSG1,CDC42,TRIM8,LAP3,MED31,CYP26A1,CHST11,CHAC2,CRYL1,PCK2,TRMT13,MGMT,FPGT,GSTA1,ATAT1,NCSTN,URAD,MAP2K1,DPH5,PSMB11,RAB18,ATP1A1,PPWD1,RIOK2,TOR1B,NDUFS6,PGM2L1,SELENOT,CYP3A43,BCKDK,IDE,HSPD1,GALNT2,COPS5,MBLAC2,CYP17A1,KLK6,VASH1,CDC23,NKIRAS2,RHBDD3,LIPA,EPHA2,SDHB,TRMT1L,RNF152,ABHD12,PDE1B,INPP5E,PIWIL2,AGO1,CERS6,PRKAB1,DDAH2,RLIM,INPPL1,DXO,MDH1,MAP3K21,RCE1,RAB33A,B4GALT3,RASL11A,LYZ,MYLIP,PYCR2,ADPRH,UGT1A1,UBE2W,RRAS2,CYP11B1,CH25H,NAA50,TUFM,VPS4A,LACC1,OLA1,SAT1,GGT7,TSSK1B,DTD2,MMD,OTULIN,FAXDC2,SETD4,CHST7,EPHA4,CNDP2,TENT5C,RBBP4,PGAP3,TST,DPP4,UBE2L3,ASRGL1,NEURL2,APMAP,GPX1,CYB561D2,FAH,CHPF,RPS3,PRDX6,KIF3C,OSGEPL1,RAP2B,SRXN1,FBXO9,ZDHHC4,MAP2K3,NAE1,ADAMTS10,PLSCR1,RAB11B,PLPP6,GLCE,NUDT2,DDX39B,PTK7,SFRP1,PML,PIWIL4,DTD1,HNMT,FAM20C,UBE2G2,ACP5,TRIM62,TOP2B,KDM4B,GTDC1,GMPS,SPHK2,SULT1B1,PTPRQ,RAB30,HMOX2,UBE2E3,DTL,PCSK2,OAS1,GK5,RABL2B,CYP4F12,AIG1,RHOB,EDEM1,RND2,CYB561,AIP,LRAT,MACROD1,DUSP18,DIO1,RAB3A,RNASEH1,HBB,FBXO3,STK4,GDE1,UPRT,SAT2,GFOD2,PRPF19,ALOX5AP,MOV10,CPXM1,HSPA5,PPP1R11,DTYMK,ASB1,GALNT12,PRSS12,EXTL2,COPS4,MCM6,SCD5,ECHDC1,RASL10A,F7,APEX2,DAPK3,DNTT,FBP1,FMO2,HMCES,TRIM36,FIG4,TLR10,ELOVL1,TRIM26,VPS18,COX10,TSN,RNF115,OCRL,NEK9,KDM2A,FURIN,PARL,AGPAT1,AK3,CHCHD4,PHYH,ARL11,PSMB10,RRAGB,SESN2,TRIM24,APEX1,CSGALNACT2,RNF181,RAB3B,ACVR1,RHBDL3,SESN3,PELI3,HELLS,POLE4,MORC2,TAF9,HDDC2,HDAC11,F2,PTAR1,RNF139,UQCRH,PDIA6,MGAT4A,DUS4L,UCKL1,PRDX2,NUDT16,ZNF451,EDEM3,IMPA2,BPGM,TRIR,PLA2G4B,APOBEC3B,CBR4,CCR5,TRIM44,SYK,PTS,CCL8,KMT5B,UBE2D1,UGDH,ACTMAP,RGS5,DUSP26,TRIM27,CYP11B2,TRIM32,RAB35,PPIL4,TRIM45,ACO1,ADAM21,RETSAT,CDK4,DHX16,HINT1,ETNK2,MEIOB,ACTB,BLVRA,ADH1B,USP30,CELA3B,NDUFB8,COX4I1,GNMT,GNG11,JAK1,ATP6V1G1,MED21,ACADSB,CA8,ACSS2,HSP90B1,BFAR,PPP2CB,CCL2,STAMBPL1,POLB,EGLN3,RHOH,ADCY3,NDUFB10,AASDHPPT,DOLK,PCYT1B,CBLL1,PLA2G5,HSD11B1,RAB8B,KDM1A,DDX5,COMTD1,GPT,NT5C2,MTMR6,MAEA,TRAF2,MMP20,DHPS,DCTD,PSMD7,PAK2,ALKBH4,CTSA,RNF167,HADHA,EPHX1,ACACA,MPG,RIGI,SMCHD1,TNKS2,PIGY,UBL4A,RNASE1,CTRB2,LBR,GSTT1,ST6GALNAC3,TYMS,IP6K1,SETD3,RASL10B,PPP2R5A,CLPB,PDE4B,CTSK,UFSP1,AREL1,FKBP2,PGS1,POLR2L,FAM98A,TRIM21,MATCAP1,GTPBP1,ACAT1,PTPN4,NTMT1,SMC4,HUWE1,HINT2,CA10,DUSP10,HTRA2,RERG,SORD,RSAD2,PARP11,MMAA,TMX3,G2E3,ACADS,RNF148,HS3ST3A1,HSD17B1,GNA14,GNPNAT1,TMX4,MME,SEPTIN7,ANAPC4,RASD1,LIG3,NDUFA5,CFTR,RBCK1,DIRAS2,GSTO1,RNF128,AANAT,CERS2,PDP2,APEH,CYGB,EMG1,UBE2I,SELENON,FTSJ3,DROSHA,ATP2C1,RALB,POLD4,BMPR2,GPN2,ATP5PF,SEPHS1,GSTP1,SBK2,PCCB,TRMT5,CTDSP1,TOR3A,FBXL3,MTMR2,PTGES3,TRMT10B,RNF126,RFC2,DDX4,PIK3CA,MET,PAFAH1B3,ELOVL7,PGM1,ACCS,PRDX3,NUDT9,ACOX1,EHHADH,KCTD10,IRF2BP1,ILVBL,DPAGT1,SULT1A3,ADO,ATP5PO,MTARC2,PRPSAP1,BPNT2,FN3KRP,RGS1,METTL14,TRIM3,CUL2,CREBBP,EYA3,B3GNT2,LCMT1,NTAQ1,CYP4V2,PIWIL3,PGAM1,PRDX1,CMA1,RPE,ALKBH5,RIT1,ERAS,ZNRF1,MAP3K12,CTDSP2,GID4,MGAT5B,RNASET2,TRIM37,DHX15,STK11,TRMT112,OTUD7B,RAB3D,NUDT3,HSP90AA1,PPTC7,RALA,GNAO1,PIP5K1A,GPHN,UBE2H,ADPRM,AKR1E2,RAP2A,NOSIP,NTPCR,MAP1S,ALKBH2,CA2,ARL5B,GDPGP1,QPCTL,FKRP,RAB39B,METTL25B,CSNK1E,DHRS11,TNIK,RBBP8,GXYLT2,ELOVL3,FITM2,PTP4A3,SETD7,MARCHF4,TXNRD3,ASPA,DHRS4L1,CHI3L1,KARS1,PDSS2,CDK5,GUK1,ATL1,TERC,HSPA13,CSNK1G3,LDHB,MPST,TOR2A,MAP3K3,SACM1L,IRAK4,PAPOLA,GNG3,IFNB1,RIT2,FRRS1,SRD5A3,SIAH2,PRCP,WWP1,SEPTIN6,ARL6,RAB37,CMTR2,FAM83B,P3H1,THTPA,NUS1,NIM1K,ALDH1A3,PSMB9,ATP8A1,CAPN1,PRKX,CDK12,DIO3,PLAAT3,STRADB,ABHD4,PSMC5,DDR1,DNAJC10,DDX39A,DIRAS1,TNFAIP1,CYP4F8,UBIAD1,SEPHS2,EXOSC1,COP1,REN,SDR42E1,TESK2,DNM2,ACOT8,LYPLA2,TRIM11,RNF8,UGT2A3,PHOSPHO2,TLR6,CYBRD1,UBE2M,UBR7,STK38L,B3GALT4,ATG7,CLU,PPIL3,PTPN22,ATP6V1A,DUSP22,CDK7,UCK2,FBXO7,USP2,OXCT1,STYK1,ABCG2,RAB32,MX1,KATNAL1,SDHC,UBE2K,MMP9,NDUFB7,CYP2D6,PLCB2,ABHD17A,PIWIL1,TYW5,CTDSPL2,SHOC1,HACD3,RC3H2,SHMT1,APOBEC3F,RPIA,UFL1,RBBP9,DCLRE1C,ALG2,DHRS7B,COX4I2,POLR3B,APOBEC3D,CNOT2,DDAH1,ARF4,CBL,UHMK1,GFPT1,RAN,AK2,PIK3R3,HSD17B10,HSD17B11,CYP4F22,PTPRZ1,RAB28,ABHD6,CAMK2G,HYAL2,OXNAD1,ACAA2,HDAC3,CHDH,UBE2F,AMT,PLCXD3,DIS3L,CHST1,GNPDA2,UGP2,PGPEP1,ATP5F1D,OGG1,CCS,ATP1A2,PYGB,TWNK,RNF5,SCYL2,POLR1H,ATP5PB,PHKA1,CHRM5,PIAS1,GFUS,GPAA1,ENPEP,CGAS,EPHB6,GNAQ,TRIM34,USP46,TENT5D,APOBEC3G,PTPMT1,DHRS4,MTHFS,RNASEK,SMPD2,PRMT6,PIP4K2C,MCM4,ANKIB1,CDC7,COX7A1,AGA,ABCC5,RGS6,SGMS1,HECW1,BMP1,STK16,PPIH,TRIM23,HECTD3,EFNA3,TSR3,RNASE9,ABHD14B,RAB33B,GNB3,RAB19,PIGK,RING1,STK3,AOX1,HRAS,MCAT,REXO2,LNX2,USP5,EED,SOSTDC1,ZBED1,ARF1,RABGGTB,STT3A,RLIG1,NDUFA4,HACD1,SUV39H1,MGME1,RHOJ,LDHAL6B,FAR2,PSMC4,GAPDH,AMY2B,APOBEC3H,GSK3A,DIO2,CMPK1,DHRS1,COX6A2,ARHGAP5,MYD88,CCT2,SMYD3,HBE1,FBXL19,AKR7A2,MAB21L1,HP,FBXO44,DHRS7,DDX46,TUBA1B,POLE3,SDS,NDST3,ST3GAL1,RNF187,VCPKMT,DTWD1,STK26,DKC1,RAB11A,METTL24,CCAR1,PREPL,LDHA,FMO3,SRP54,ADAMTS1,MED10,AIFM1,HACD2,RNF34,EGR2,NAA16,HERC4,ZDHHC16,HBA1,YES1,PSEN1,MYG1,ARF6,TRIM54,DNAJC27,PPP5C,GGH,RABL3,KIT,PPIF,G6PC3,TAF10,YBEY,SENP8,ST6GAL1,UBE2B,AZGP1,GSTA2,NME4,PRSS37,DDX1,COX8A,SSH3,MVD,RNF40,UBE2S,NDUFA12,ACOT13,GTF2B,DCK,CAMKV,DNASE1L1,GLT8D2,MED30,CAMK1,B4GALT1,TXNDC17,SYVN1,DUSP6,CCL3,GDPD3,DTWD2,USP14,COMT,UGCG,HTRA1,GXYLT1,RARS1,TMEM59,ABHD8,WSCD1,RHOBTB3,GNG10,GFM1,UBE3A,HSPA8,SLC25A42,CDIPT,SARM1,GSTM2,EXOSC3,IFT22,MYRF,ATP1A3,GCNT3,ERCC3,B3GALNT1,UBLCP1,CNOT6,PDE1A,DDX50,MMACHC,FBXO25,GLRX2,CHST2,RAB6B,HPGDS,IGF1R,CDKN3,MARCHF5,WWP2,RND3,PTPN11,IFIH1,CDK20,AGPAT5,CHRM1,ACOT6,RAB5C,CLCA1,CHRM3,TNKS,FEN1,TESK1,CSNK1A1,DCP2,EEF1AKMT3,CYP7A1,HSD17B3,UBA3,COQ8B,VKORC1L1,DLST,GUCY1B1,ZMPSTE24,MRAS,HR,NEU1,BUD23,PIK3CG,HADH,CCND1,PXYLP1,CASP4,METTL18,SRM,FRA10AC1,ENO2,KDSR,TRIM52,GYS1,PAK6,GCLC,KLK3,UBE2E2,TPST1,ARL4A,CBR3,RCL1,PIGW,TRMT61A,GALC,RRM1,RNF14,ISYNA1,NAA11,CDKN1A,XRCC5,CD38,ARG2,PPP1CC,LANCL1,RAB1A,SHPRH,SUCLG2,SGMS2,CYB5A,NUDT4,SPR,AGAP1,GPX4,PRSS23,RFC4,KGD4,PPM1M,ABCE1,ABHD2,FDFT1,TENT4A,RNASE6,IKBKB,EP300,EXT1,FKTN,HARBI1,RAB29,PTEN,NRP1,XXYLT1,HS2ST1,TECR,ADK,NTRK2,B4GALT6,PADI2,AKR1C2,PRKCA,G3BP1,ST3GAL5,HSP90AB1,B3GALT1,G6PD,IDH3A,VRK1,PDE2A,HEXA,HSPA14,AHCYL1,CARS1,SRPRA,DYRK1A,PCBD1,NDUFV2,VPS72,GSTM4,ZDHHC14,CYP21A2,BAZ1B,MGAT1,POLR1B,PCMTD1,OGFOD3,GNPDA1,TRMO,EEF1A1,RGN,ABCB9,CCT5,ENTPD3,ATG4A,OARD1,ELOVL6,TLCD3B,RAB31,DYRK2,MAT2A,NMRK1,TENT2,TRIM68,CDK8,IMMP2L,METTL6,ROCK2,SMURF1,ENPP4,CYB5R1,ENTPD4,LYZL4,HMGB1,PRKCQ,JAK2,HSDL2,METTL21A,PLCL1,FGFR1,AGAP2,P4HA2,MLH3,B4GALT7,F10,DPH6,GLYAT,PGK1,CTSB,RPP21,KIF3B,ARMT1,PPT1,PMPCA,UCK1,QNG1,FBP2,FMO1,INPP4A,ABHD5,ADCK1,ACER3,RPS6KA4,RAB22A,NME2,CYP2C9,ZDHHC17,EZH2,ODC1,ETFA,RSBN1L,PSMB7,DUSP14,PIM2,FAHD1,PAFAH1B2,OGDHL,NUDT19,SOD2,AK5,DAPK1,DHRS13,TLR4,GALNT1,SAR1B,NLRP3,PPM1D,ATAD1,ALPL,CRY1,PARP2,USP13,AMACR,WDSUB1,RTCB,TUBA1A,TRIM5,DPEP1,MAPKAPK5,ANAPC11,HBM,WSB1,PGA4,MED11,IAH1,RUVBL1,GNB1,MX2,PPID,E4F1,ATP5MG,STK24,CMAS,PSMC3,ACTA2,FTH1,RAG1,MECR,MDM2,ACO2,APOBEC3C,HS3ST1,PPIG,INMT,FBXO22,OTULINL,PPP1R8,PTRH2,PDE7A,PSMB6,PCGF3,PLAAT5,MAP3K14,DICER1,ADAMTS20,SENP5,ROCK1,ELOVL4,TERT,TRAF7,PSMC1,POP5,UFD1,USP39,THG1L,COX5A,DDI1,PIP4P2,TMX2,PCSK9,CHST10,CRYZ,PGAP4,FBXO30,NTRK3,CYP2C18,ALG11,AKR1C1,TGFBR2,CHPF2,PREP,FGR,GPX2,GPAM,CYP3A5,PPP3CA,GLYATL3,MTG2,RPP25,CYB5R3,FKBP8,C1GALT1C1,PCNA,KIF2A,CDK9,MAPK4,MARCHF9,PAK5,MUL1,RAC2,PPIB,PLA2G15,IDO1,DHX38,GLUL,B4GALT4,PDE9A,HS3ST5,TRAF6,RHOG,TRIM6,POLR2B,TPH2,SNRK,PRKD3,RNF11,ABCC2,METAP2,TRMT11,RAB40AL,PBLD,DOHH,COX6B1,USP38,USP16,PRSS8,OTUD6B,TRIM35,DUSP3,METTL22,FARSA,MINDY3,ERP29,PCMTD2,RGS19,INPP5K,CA14,GAL3ST1,NLRP1,NUDT18,HMBS,RAB3C,CISD1,MGST3,RNF208,MEAF6,SEC11A,GSTT2B,ABCB1,FKBP14,HMGCS1,ZDHHC8,RFC5,SAMHD1,TP53I3,ARL4D,DIRAS3,TRAF3IP2,ADH1A,ADAT1,SIRT7,HSDL1,FNTB,CYP27A1,DHX9,RAB6A,RNF146,SELENOO,EIF4A3,CHKB,DECR2,MSRB3,HSD17B6,GGCX,PRKACB,NDST1,PNP,TNFAIP3,IDH1,ADTRP,KRAS,VPS4B,ACP2,POLL,PYROXD2,PAPOLB,LYPLAL1,MCM8,PAPSS2,HINT3,RNF7,EZH1,TLR2,RIMKLA,PPAT,PPP1R3C,OAT,GNL1,TRIM10,CHMP1A,TSNAX,NDUFB5,GFOD1,CYC1,CCT7,AGK,PGGT1B,GAMT,SMARCE1,RAB4A,NT5C3A,RNF144B,RAB13,SELENOF,PLD3,AZIN2,CSNK1A1L,CYP1B1,ATG3,RNF103,KCNAB1,CLK4,FKBP1B,ABHD10,AKT3,TAB1,PIK3R1,NUDT5,GNA11,AKR1B1,PPM1K,USP3,QTRT2,DCAKD,POLR1D,CLIC2,TMT1B,ST3GAL4,CNOT8,MORC4,LARGE1,GPD2,RAF1 |
| 2.235e-04 | -8.41 | carbohydrate metabolic process | biological process | GO:0005975 | 440 | 164 | 18204 | 5365 |
PDHB,AKR1B1,ATF3,FBP1,MPDU1,FKRP,PFKFB2,LDHA,NPY1R,KBTBD2,PGM2L1,GCLC,GK2,BRS3,PGAM1,AKT1,SDS,SLC2A3,HYAL2,SLC23A2,UCP2,STBD1,CHST9,ADIPOQ,TNF,SLC2A1,RPIA,CRTC2,PPP1R3C,FPGT,ST6GALNAC3,GK5,EDEM2,FUT8,GDPGP1,RPE,CHST7,BPGM,ATP1A2,GYS1,CHST11,PYGB,SIAE,ADRB3,CHST2,PDHA1,GHRL,GANC,RGN,G6PD,CSGALNACT2,ST8SIA5,B3GALT2,FUT9,SLC25A10,AKR1A1,GSK3A,CRY1,PPP1CC,BAD,OAS1,IDH1,B4GALT7,PHKA1,INPPL1,CHI3L1,UGP2,EDEM1,B4GALT1,ATG3,IL6ST,ST3GAL4,B3GALT1,GAL3ST4,LANCL1,GNMT,ATF4,WDR45,SORD,GPD2,ENO2,PPARA,IDH2,LEP,KCNJ11,PTGES3,EXT1,AKT2,CHST1,HAS3,COMT,OVGP1,RB1CC1,DLAT,HTR2A,ENO1,SLC37A4,FUT1,PMM2,ERRFI1,PGM1,HEXA,NDST1,PPP1R1A,IER3,LEPR,SLC25A1,CSGALNACT1,SLC35A1,G6PC3,SLC2A8,GNPTG,CHST10,FBP2,PIK3CA,GBE1,GLO1,PYGM,CHST13,IDH3A,TP53,HS2ST1,LIPA,PHKG1,ST8SIA4,PGK1,MDH1,SLC35A2,B3GALNT1,ST3GAL2,B4GALT6,B3GALT4,PPP1R2,GNPDA1,PCK2,GSTO2,NUDT5,B4GALT3,MAN1A2,GSTO1,TKTL1,OGDHL,SLC25A12,PHKB,GABARAPL1,EDEM3,SLC25A11,MYORG,LANCL2,GANAB,HEXB,NEU1,PPP1CB,CHID1,PC,AMY2B,GALE,GCNT3,GNPDA2,NDST3,GAPDH,FABP5,B4GALT4,AKR7A2 |
| 2.244e-04 | -8.40 | negative regulation of protein kinase activity | biological process | GO:0006469 | 170 | 72 | 18204 | 5365 |
DUSP22,IFNG,MIR24-1,CHP1,DUSP3,YWHAG,ADIPOQ,TAF7,SPRED1,CAMK2N1,DBNDD1,DUSP1,HSPB1,MIR15A,DUSP19,PPIA,GNAQ,MIR34A,RTRAF,GSTP1,HYAL2,PDCD4,HEXIM2,ERRFI1,IL1B,RGS2,PTPN1,AKT1,INPP5K,PTPN22,PTPRQ,CORO1C,TRIM27,STK38,DUSP10,PKIA,PYCARD,THY1,SOCS4,HEXIM1,SPRY1,CDKN1A,LRP6,MACROH2A1,PKIB,PTEN,CAV1,TSG101,UBASH3B,RB1,CAV3,DEFB114,CEP85,CDK5RAP3,TESK1,CBL,CAMK2N2,MIR711,GADD45A,GSKIP,CDKN1B,MIR20A,SOCS5,PKIG,PAQR3,LILRB4,TRIB1,SLC8A1,PAK2,PPARG,SFN,MIR218-1 |
| 2.250e-04 | -8.40 | ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17) | protein interactions | 23390 | 277 | 105 | 19454 | 5460 |
RNF20,EIF3E,SOX14,BSCL2,LPAR2,MRFAP1,GAD2,YIF1A,SNAP23,IFT57,GABPB1,CAPN2,OTX2,EEF1A1,SNAP25,LY6G6C,RAB39B,SRPRA,ADD1,RAP1B,DELE1,TPGS2,GOLPH3L,UBE2K,LPAR1,VIPR1,TNFAIP1,CHMP1A,GPR35,ZCCHC17,HCST,CNP,NRSN2,F11R,TXNDC12,SLC25A31,OPTN,GSK3A,PPP2R5E,STN1,ARFGAP3,PPTC7,TYROBP,SPRED1,H2BC9,DNAJC5,KRAS,LASP1,ASF1A,SRSF4,MRFAP1L1,HECTD3,ACTR1B,SKA3,SMARCB1,KHDC4,FUT9,KIAA0408,LPAR6,LCA5L,RANGRF,SP2,SPRED2,RBM5,CSTA,PDZK1IP1,RSBN1L,ANKRD50,TOX,PIK3R1,HMBS,MDFI,GABBR1,MLH3,GPM6A,EYA3,EEF1G,TACR3,ZDHHC17,CDSN,TNFSF10,FTL,EXD2,TSPAN15,DR1,TMEM115,FAM8A1,CNDP2,ALKBH3,PLSCR4,B4GALT3,TMCC1,LMBR1L,DLG4,SCNM1,PRMT5,WDR20,GRB10,THAP7,BTF3,OTUD7B,AK3,TTC23,STX16,SLC1A3 |
| 2.251e-04 | -8.40 | INO80B (INO80 complex subunit B) | protein interactions | 83444 | 166 | 68 | 19454 | 5460 |
BRD3,DICER1,SSX2IP,RPS2,RPL24,BCL7C,CD81,RPL6,INO80E,PRPF19,DDX50,DHX15,EGLN3,RPL7,RPS16,RPLP2,CDR2L,BOLL,ALYREF,RPL8,RPL12,RPL18,ZNF526,PNMA2,THAP1,TRAF2,KIF1C,RPL17,RPL28,RUVBL1,DHX9,INO80C,RPL3,PICK1,RUVBL2,RPL23A,HAPSTR1,TFPT,RPL31,HSPD1,FBXO3,FTSJ3,CCDC85B,CEP70,GPRASP3,RPL7A,STAC3,CIAO1,SRPK2,RPL19,POLR2B,ACTB,CSNK2B,TRIM27,TNFRSF1B,RPS3,PNMA1,RPLP0,E2F6,MYLIP,ACTL6A,RPL27A,RPL4,YAF2,DDX5,SQSTM1,DDX46,RPL27 |
| 2.257e-04 | -8.40 | SYT6 (synaptotagmin 6) | protein interactions | 148281 | 117 | 51 | 19454 | 5460 |
EHD4,NSDHL,SFXN1,VTA1,PRPS1,SAR1B,RDH11,AHCYL1,CSE1L,VRK1,SLC29A1,NAA15,SUPT5H,FAM162A,PTRH2,RAP1B,CETN3,PTPN1,SRPRA,DNM2,CNTROB,ALCAM,RAB1B,GAPDH,TMEM70,PRKCB,FXR2,TOMM22,LMNA,RPRD1B,IDH2,TRIM27,VAMP3,CYB5R3,CYRIB,CSTF3,UQCRQ,TNPO3,F11R,KCTD9,RAB14,YES1,RNF40,HMOX2,GALE,NAA50,TRIM32,PTPN11,GSTK1,ZMPSTE24,BRCA1 |
| 2.257e-04 | -8.40 | DUSP23 (dual specificity phosphatase 23) | protein interactions | 54935 | 117 | 51 | 19454 | 5460 |
EED,RPL8,PSME2,HAX1,TAF9,TMEM70,SHC1,ESYT1,SLC25A26,PRDX4,ADD2,DUSP21,MCM6,CSE1L,FN3KRP,CTNNBL1,PDIA6,CLPB,OTULIN,MTA2,IK,TFRC,EXOSC8,TUBA1A,MTCH2,ESR2,PRRC2A,UBA3,SEC63,APEX1,HDDC2,TMOD3,RRAS2,GANAB,RAB28,ZMPSTE24,XPOT,RBM27,NIF3L1,CIRBP,MCM4,BAG3,SUGP1,MRPL20,CCDC186,DUSP26,PIH1D1,UBE2M,SSR1,DUSP22,DDIT4L |
| 2.257e-04 | -8.40 | EMC3 (ER membrane protein complex subunit 3) | protein interactions | 55831 | 117 | 51 | 19454 | 5460 |
RB1CC1,RHOG,ESYT1,SCGB1D1,EMC6,SLC25A46,EMC4,TMEM237,DNAJC1,RHOH,DERL2,RAC2,MTAP,PTPN1,PLAC9,SLC4A8,CYB5B,RPN1,DNAJC25,MAK16,CCDC47,EMC10,FKBP8,EMC8,ADIPOQ,TMEM33,EMC2,FIS1,UBE2H,SDF2L1,SPOP,CSGALNACT2,NDUFB6,SEC63,COPE,RPGRIP1L,RMDN3,SEC61B,LMBR1L,RPA2,UBAC2,EMC9,CDC42,RND2,OTULINL,ST7,EDEM3,DNAJC22,EMC1,GNRH1,RPA3 |
| 2.265e-04 | -8.39 | BATF (basic leucine zipper ATF-like transcription factor) | protein interactions | 10538 | 23 | 15 | 19454 | 5460 |
JUNB,NFIL3,CEBPE,KDM1A,CEBPG,DDIT3,COX8A,FOS,ATF3,JUN,IRF4,ATF4,SNAPC5,BATF,IFI35 |
| 2.268e-04 | -8.39 | regulation of cell growth | biological process | GO:0001558 | 401 | 151 | 18204 | 5365 |
BMPR2,BAP1,VGLL4,CDKN2D,ESR2,UCN,EI24,VEGFA,SEMA7A,RERG,LAMTOR2,EFNA5,NDUFS3,CAV3,CDKN2AIP,MAD2L2,SIN3A,CYP27B1,MTPN,MEAF6,MECP2,FXN,CLSTN3,IGFBP3,ANAPC2,SYT4,SFN,DNAJB2,TP53TG5,OSGIN2,HBEGF,CGRRF1,CDC73,MIR208A,KLHL22,DNM2,CDKN1B,RTN4,SMURF1,PRKCQ,SESN2,PI16,BRCA1,SFRP1,BTG1,CDC42,CRYAB,SYT2,SOCS2,SDCBP,PAFAH1B1,FOXP1,MMP14,TP53,TMEM196,TOMM70,JADE1,PPARA,PAK5,FRZB,CRABP2,PSRC1,CCDC85B,ENO1,SH3BP4,DCUN1D3,L1CAM,SERTAD3,EGLN2,GSK3A,LGI1,RGMA,ADNP,FGF13,CTTN,IGFBP4,RB1,PSMD10,RASGRP2,DISC1,TSG101,SPHK2,BST2,PML,NRP1,CDKN1A,DNPH1,ING5,TMEM97,F2,IL2,PLAA,IFRD1,RND2,CRKL,GJA1,CD38,LAMTOR1,CSNK2A1,EXOSC4,DDR1,G6PD,TNR,CCN3,TRIM32,CDKN2C,MSX1,MAP1B,HYAL2,MT3,TFRC,RAB33B,PHB1,SLC23A2,ING1,IGF1,NAIF1,DCUN1D5,CRLF3,RBBP7,TTL,TGFB2,SMAD3,MUL1,PPT1,PARP2,SEMA5A,EAF2,CXCR4,S100A8,TRIM46,FBP1,HDAC6,STK11,SERTAD2,GREM1,SMAD4,ADIPOR1,CCAR2,FAM107A,BCL6,CXCL12,AKT1,DERL2,SPOCK1,CISH,ACVR1B,SPP1,RGS2,CDK5,MINAR1 |
| 2.269e-04 | -8.39 | RPTOR (regulatory associated protein of MTOR complex 1) | protein interactions | 57521 | 317 | 118 | 19454 | 5460 |
GNG2,TPM3,MOV10,EDEM1,LAMTOR2,ESYT1,LANCL2,RAP1B,EEF1B2,EIF4E2,KCTD3,PGM1,TBK1,CCT5,HSPA13,RAB1A,PPDPF,PTGES3,FKBP8,TNFSF8,EIF4EBP2,KPNA2,RPS17,TUFM,AKT1,CCNB1,RPL7A,CA2,POLR3H,PTEN,CCNF,TUBA1B,ENO1,VIRMA,LDHA,SIPA1L1,PSMC4,UBE2M,STAMBP,GSTP1,RARS1,HEXIM1,SHOC2,HPS6,RPA2,SQSTM1,RAB9A,EIF4E,RPL4,ATG7,YWHAG,XPO1,HSPB8,YWHAH,PDIA3,LAMP2,SLC38A7,RB1CC1,IKBKB,PDCD1,TRAF6,SRSF1,EGLN3,CACYBP,CCT7,HSP90AB1,HNRNPL,TCP1,MITF,TUBA1A,FAF2,TOP3B,TUBB4B,CDK5,BAG2,TESK2,RPL31,PABPC1,CCT8,RPS4X,IMMP2L,PSMA1,KRAS,RRAGB,CDK20,RUVBL1,RHEB,BAG3,MYC,LDHB,HSP90AA1,NTRK3,RGMA,LAMTOR1,CCT2,ATG3,YWHAZ,BRCA1,CD79B,LMBR1L,RAN,GNB1,TUBB,RBBP4,LAMTOR3,TIRAP,PPP1CB,RRAGA,INPP5E,PSMB3,PIH1D1,FKBP1A,MED23,EP300,DDX39B,RTKN,NRBF2,HSCB |
| 2.269e-04 | -8.39 | SRRT (serrate, RNA effector molecule) | protein interactions | 51593 | 317 | 118 | 19454 | 5460 |
ELAVL2,ZBTB38,SERPINB1,RBM7,UBE2H,SMARCA5,FBXO7,NTAQ1,AR,PPP1CC,NDN,VIRMA,SRPK2,PSPC1,CCNF,EIF4A3,PHAX,MACROH2A1,JUP,UBE2M,DYRK2,SF3A1,MX1,CCNA2,NUCKS1,HMGB1,MBD3,HSPA5,AATF,RPA3,SNRNP70,CD9,USP2,CSNK2A1,FZR1,SPPL3,RPL35A,TOP1,RBM42,NCBP2,ALDH1A3,CD274,ALYREF,CBX3,CRABP2,APEH,NUPR1,FURIN,FBP1,FAM162A,BPIFA2,HNRNPK,KPNA2,SNIP1,HAPSTR1,RING1,DHX9,SP1,OSGEP,DHRS1,POLR1B,RIT1,MYC,NIBAN2,CUL3,RNF40,HMGCS1,CPSF2,CAPG,SNRPB,MCM4,AKR1C2,SNRNP40,TRIM29,SNRPB2,ESR2,SNRPD2,GTF2F2,VAV2,CRYAB,SOST,PIH1D1,PABPC5,WDR77,STAU1,SAP18,SNRPA,DDX39B,HSPA8,SF3B1,PSMA3,EP300,HNRNPA1,XPO1,YWHAH,TRA2A,WDR11,HNRNPL,PAIP1,HYPK,SUMO2,SRSF10,PHB1,EED,MAGED2,PDHA1,RND3,ZNF263,RAF1,DHX38,LGR4,GTF2E2,G3BP1,MCM6,SAR1B,SSRP1,EWSR1,SRSF7 |
| 2.270e-04 | -8.39 | ACTBL2 (actin beta like 2) | protein interactions | 345651 | 274 | 104 | 19454 | 5460 |
MYC,CUL3,CUL2,BTF3,HSD17B3,MCM3,CCT2,LRRC20,MYO6,ATG3,CYP1A1,SP1,VMP1,VEGFA,PNMA1,CCDC90B,INTS10,ACTB,PPP1R3C,ESR2,ELK4,ZNF428,PIH1D1,DCTN3,UFL1,NPTN,UBXN6,BCL7C,AGR2,CBL,PPP2CB,OPRL1,CCT7,CRYGD,ERRFI1,SOX2,ISG15,GTF2E2,SAP30,NGB,BCL7B,CCT8,UBE3A,G3BP1,ATP5F1D,TRIM37,RAD21,CAP2,TAS2R7,CFL1,USP14,NCAPG2,RC3H2,PTTG1,NRP1,TRIM24,ZMAT5,KCTD9,TMOD3,BUB3,SH3BGRL,HOMER1,PPP1R1B,DUSP10,CEP97,NEK2,CFTR,RPA2,HEXIM1,RPA3,TEX264,BAP1,VIP,PIAS1,DNLZ,DPP4,RBM17,HDAC6,COPS5,TPGS2,TMEM70,OSBPL8,ACTA2,TES,CAND1,KCTD15,DCUN1D1,TMCC2,CDK9,TP53,CCT5,ARHGAP12,RPL15,TFCP2,DISC1,NUPR1,SLC25A11,NEDD8,H3C1,NUP107,WASL,MEPCE,FBXO25,DUSP19 |
| 2.270e-04 | -8.39 | WDR12 (WD repeat domain 12) | protein interactions | 55759 | 137 | 58 | 19454 | 5460 |
PSPC1,OPTN,CCNF,PRKRA,CSNK2B,TSN,RPL7L1,FBXO22,SRPK2,ESR2,MYC,TUFM,USP14,FBXW11,FTSJ3,DNAJB6,RIT1,PPM1G,RPA3,SIRT7,MTDH,RNF113A,DGCR8,NPM3,RPL4,STAU1,WDR55,BRIX1,RPA2,TBC1D13,PPP2CB,KRR1,MRTO4,TSG101,LYAR,PRNP,RPL7,IFI16,XPO1,CSNK2A1,DDRGK1,WDR12,CHCHD1,H2AC4,SNRNP70,RPL3,RTCB,KRAS,TOM1,DNAAF10,RPL28,SEPHS1,HNRNPDL,RAF1,TP53,H1-3,CHMP4C,MOB3C |
| 2.274e-04 | -8.39 | establishment of protein localization to endoplasmic reticulum | biological process | GO:0072599 | 45 | 25 | 18204 | 5365 |
ZFAND2B,SEC63,SPCS1,SRP14,SEC61A2,SRPRA,SPCS3,TRAM1L1,SEC61G,ZFAND2A,SEC62,EDEM1,SRP54,SRPRB,SGTA,VPS54,SSR3,SEC61B,TRAM2,UBL4A,SRP72,SPCS2,HSPA5,SEC61A1,TRAM1 |
| 2.289e-04 | -8.38 | regulation of chemokine production | biological process | GO:0032642 | 104 | 48 | 18204 | 5365 |
MIR106A,MYD88,TLR2,EIF2AK2,TLR9,MIR214,MIR17,SOCS5,LILRB4,MIR146A,SNAI2,AIF1,MAVS,EGR1,TIRAP,TLR7,TICAM1,IL7,OAS1,ARG2,EPHA2,IL1B,HMGB1,SYK,MIR26B,IL18,MIF,PYCARD,MIR140,AGER,TLR4,KLF4,MIR590,DEFB124,TLR3,IFNG,MUL1,IL10,FOXP1,IL17F,ADIPOQ,TNF,MIR34A,SELENOK,TRIM32,GSTP1,CLEC7A,IL6 |
| 2.289e-04 | -8.38 | somatodendritic compartment | cellular component | GO:0036477 | 842 | 291 | 19108 | 5553 |
GCHFR,CRMP1,TXNRD2,CYGB,SERPINI1,KCNA2,SNCG,CDC42,NRSN2,SLC2A3,KCND2,ENC1,NEGR1,GLRB,ATXN10,OPRM1,TOP1,MAP1S,NSG1,RGS7BP,CPEB1,PICALM,SNX14,PPP3CA,CCR4,LAMP5,TIAM1,ELFN1,ATP1A2,SLC38A2,IFT52,RPL28,PPP1CC,ATXN1L,EFHC1,PSEN1,CAPN2,LHFPL4,CASC3,LYPD6,SOD1,GRIA1,ABHD12,MIR107,UCN,MT3,S100B,GNB3,GSK3A,IGF1R,UBB,BMPR2,AKAP12,PTK7,CLSTN3,GHR,GRIA2,MTMR2,RAB5A,FKBP4,CCN3,BMPR1A,SIPA1L1,OPHN1,KLHL1,PDYN,ABHD17A,LRP6,KCNIP2,PTEN,SARM1,BECN1,IGF2BP1,SLC6A1,LPAR1,SLC1A3,MAGOHB,GNG13,BAG2,GABBR1,IFT57,TACR3,P2RY1,ADNP,STMN2,ENO2,LRFN3,TMEM100,AZIN2,PYCARD,CX3CR1,JPH4,TACR1,CPLX2,KCND3,BMPR1B,CYP17A1,LDLR,PPT1,HPCA,CAMK2N1,EPHB6,CRHBP,DYRK1A,RIC3,TNF,INHA,DRP2,BRINP1,FZD4,SIAH2,NDN,HDAC6,SST,CCR2,TGFB3,SMURF1,CSNK1E,PSD2,HTR2A,EIF4A3,TRAPPC4,USP8,SNAP25,KCNB1,DLG4,CTTNBP2,ADCY2,TGFB2,ARF4,ADORA1,G3BP1,ROGDI,KLHL24,NGDN,EPHA4,GPM6A,LGI1,ATP1A3,GABRA2,PPP1R1B,HSP90AA1,PRSS12,GLRA1,SLC12A2,VTI1B,TPBG,NCDN,SNCB,PNOC,YKT6,PPP2R1A,ABHD13,BRINP3,TMEM108,CLU,ASIC2,OPRK1,CTTN,ATF4,PRNP,SYNDIG1,ALCAM,CDK5R1,KCNC1,SLC6A6,PMM2,SYT4,SLITRK2,MAX,COMT,HTR1F,SLC25A27,HTR5A,ELAVL4,FBXW11,ZC3H14,FCGR2B,PHAX,THY1,RBM3,GNG3,SLC32A1,HOMER3,CACNG3,SLC4A8,HRH2,GNAZ,FGF13,CHRM3,HTR1A,TNFRSF1B,SCN1B,NLGN1,NLGN2,SLC8A1,KIF1C,RCVRN,RIT2,BRINP2,PDLIM4,HRH3,GLRX2,SLC4A10,MME,AMIGO1,SRSF10,C9orf72,PDE1A,SMN1,GRM2,NDFIP1,CD40,PDE4B,HSP90AB1,ERO1A,GABRG2,CPLX1,LYNX1,TRIM3,FUBP3,PCSK2,ELK1,DRD1,TMEM266,RAB27A,MUL1,BGLAP,KCNH1,GNAI2,TRAK2,GLRX5,IL6ST,MAP1B,MOB4,NTF4,PAFAH1B1,RRM1,CTNND1,GABRA1,GPHN,CX3CL1,ZC4H2,STAU1,ASTN1,L1CAM,SLC38A7,CHRM5,HOMER1,FEZ1,SRC,CRYAB,SLC38A1,CD200,CDK5,PDE1B,KCNJ2,SLC1A1,UHMK1,BACE1,GPR37,GAD2,SLC6A3,KPNA1,NQO1,LRRC4,ADORA3,CHRM1,CHRM4,KCNJ11,PPFIA2,HSPA8,TAC1,PDE9A,SLC6A2,ADAM21,FBXO31,NRSN1,GRM1,UPF3B,NTRK2,ATP6AP2,TMEM50A,FZD3,STAT1,KIF3B,TMEM185A,GNAO1,CD2AP,ABITRAM,PGRMC1 |
| 2.289e-04 | -8.38 | GTF2H4 (general transcription factor IIH subunit 4) | protein interactions | 2968 | 103 | 46 | 19454 | 5460 |
MYC,RIT1,BRCA1,CDC7,PRSS8,GTF2H2,GTF2F1,ADPRM,MRPS21,MED17,CCNH,PRMT2,CDK7,GTF2H4,FKBP10,GTF2H5,EXOSC4,SNAPC1,RNF11,GRPEL1,TUSC2,KDM1A,EMC1,STAU1,GTF2E1,DDRGK1,ERCC3,EMC4,RBM17,BRD3,MED21,RPL24,RPLP2,GTF2B,CDK9,CETN2,SPPL3,MGARP,TP53,SREK1IP1,EIF1AD,SFXN1,TCOF1,MNAT1,KRAS,CAMK2G |
| 2.289e-04 | -8.38 | SAT1 (spermidine/spermine N1-acetyltransferase 1) | protein interactions | 6303 | 103 | 46 | 19454 | 5460 |
MRPL12,SNAI2,COX6C,MED31,EVA1A,SAT1,EEF1G,PTN,UBE2D3,NTAQ1,SPMIP10,FTSJ3,NIF3L1,CRMP1,CCHCR1,CCDC90B,TACO1,B4GALT3,PRDX2,JUNB,LRIF1,RPP25,TP53,KHDC4,DDX39A,TNNI1,BHLHA9,INO80C,ERG28,HSPE1,PSMA1,SEPHS1,RIGI,RBM17,TLE1,EIF3D,MRPL9,SAT2,CSNK2A1,HSPB1,RPLP1,ZHX1,FAM156A,PLGRKT,EPHB6,FUNDC2 |
| 2.289e-04 | -8.38 | ZFYVE9 (zinc finger FYVE-type containing 9) | protein interactions | 9372 | 103 | 46 | 19454 | 5460 |
SCYL2,NTRK2,TGFBR2,EPHA4,KRAS,FLOT1,SUPT5H,PPP2R1A,RAB4A,TFRC,RAB35,SMAD3,TSG101,GJA1,ARF6,CAV1,STX6,EGLN3,RAB5C,DPP4,ATG9A,LAMP2,CTNNB1,LAMP3,STYK1,PML,RAB9A,RAB5A,RNF11,STX7,ST7,RND2,PPP1CB,FGFR1,JUP,LRP12,RHOJ,VIRMA,RAB11A,CUL3,PPP1CC,MYO6,RHOB,LAMTOR1,NCKIPSD,SMAD2 |
| 2.293e-04 | -8.38 | vesicle fusion | biological process | GO:0006906 | 96 | 45 | 18204 | 5365 |
CLTRN,VAMP7,VPS4A,GOSR1,CHMP1A,TOM1,GOSR2,STX10,SEC22B,VAMP1,STX5,VPS39,STXBP6,STX11,STX16,SNAP25,STX8,SNAP29,CHMP1B,VAMP8,STX1A,VPS33A,VTI1B,VIPAS39,VPS18,SNAPIN,CHMP2B,STX7,CAV2,PLA2G5,VAMP2,CHMP2A,STXBP1,YIPF4,BET1,YIPF5,SYT4,STX17,CHMP4C,VAMP3,VPS16,STX12,CHMP5,SNAP23,STX6 |
| 2.293e-04 | -8.38 | regulation of muscle adaptation | biological process | GO:0043502 | 96 | 45 | 18204 | 5365 |
FBXO32,ROCK1,MIR1-1,MEF2A,MIR145,FOXP1,IGF1,MIR34B,SMAD3,PARP2,CAMK2G,ROCK2,IL6ST,TOMM70,MIR208B,HAND2,PPARA,SMAD4,LMNA,PPP3CA,ADRA1A,DAG1,MIR34C,RGS2,MIR25,GSK3A,CAV3,ATP2B4,MTPN,BECN1,TNNI1,PPARG,TRIM63,SELENON,MIR21,MIR208A,TNFRSF1B,PRKCA,GTF2IRD1,MIR17,MIR214,PDE9A,MIR20A,G6PD,PI16 |
| 2.293e-04 | -8.38 | mitochondrial respiratory chain complex assembly | biological process | GO:0033108 | 96 | 45 | 18204 | 5365 |
NDUFB7,NDUFA5,NDUFA12,SDHAF2,COX14,UQCC6,NDUFAF6,NDUFB10,NDUFAB1,NDUFS8,NDUFA1,COX19,UQCC2,AIFM1,NDUFB6,UQCC3,IMMP2L,NDUFAF2,COX20,BCS1L,NDUFS2,NDUFAF3,COX16,PET117,TIMM21,NDUFAF4,TMEM126A,NDUFB8,NDUFA2,COA4,TMEM126B,LYRM2,NDUFC2,COA5,TACO1,TAFAZZIN,COA1,NDUFB5,SDHAF1,NDUFS3,SAMM50,NDUFB4,COX17,SDHAF4,CHCHD4 |
| 2.297e-04 | -8.38 | CORO1C (coronin 1C) | protein interactions | 23603 | 314 | 117 | 19454 | 5460 |
WTAP,CYC1,FGFR1,HSP90B1,WWP1,RPA2,CFTR,UQCRC1,NEK2,CDC42,HSPA5,PIAS1,PIK3R2,PDHB,DLAT,CORO6,BAP1,RPA3,UBE2H,RC3H2,PPP1CC,TUFM,HMOX2,RSPH1,GNAI2,UQCRQ,SH3BGRL,DAPK1,UBASH3B,CTTN,UQCRC2,CCNF,RAD23B,NUPR1,DISC1,CAPZA2,NDUFS3,ACTR2,TFCP2,MTCH2,TP53,PREB,KBTBD4,UBL4A,DUSP19,EMC2,ABCE1,MRFAP1,BHLHE40,FGR,SHC1,POR,HDAC6,DPP4,KARS1,CDK9,TES,COX4I1,HACD3,HRAS,CD274,NDUFA5,MMP14,TIMP4,MED23,ETF1,ELK4,PPP1CB,TOMM22,WDR77,SKP1,PHB2,NDUFS2,UFL1,HADHA,NMRAL1,HACD1,HTR1A,DDX39B,DNAJC3,RHOB,PCCB,TOMM40,BTF3,CUL3,PAPOLA,NIBAN2,MYC,LMO2,ESR2,ACTB,FBXO22,ATP5F1B,PHKB,AP2M1,DLST,GTPBP1,CYB5B,PDHA1,CHMP4C,EZH2,TRIM37,ROCK2,VDAC1,KRAS,EMC8,NDUFB8,MED4,CBL,AGR2,NDUFV2,VPS26A,PDIA3,UQCRH,NDUFS8,ATP6V1A,PHB1 |
| 2.297e-04 | -8.38 | ELOB (elongin B) | protein interactions | 6923 | 314 | 117 | 19454 | 5460 |
SOCS4,COQ8A,ITK,LRRC14,PRNP,ASB11,FZR1,DCUN1D1,ELOC,COPS5,NFKB1,EPOP,PSME1,SPSB1,CAPZA1,RIGI,SOCS2,NEDD8,SOCS3,MAP1LC3B,TNNI3K,SPSB3,PCMTD2,RPS20,RNF187,PSMC5,CTNNA1,MRPL53,SRC,ADRM1,GABPA,CEBPE,ST13,UBE2H,CDC73,NAPA,RC3H2,RNF113A,SQSTM1,RPA3,BAP1,GTF2I,WSB1,CFTR,CDC42,ATG16L1,KLF4,UBE2M,OXSR1,METTL14,RPA2,COPS2,S100A8,METTL25B,CBFB,DHX15,EGLN3,OSBP,COPS7B,CISH,FEM1B,DDRGK1,ATG7,PFDN5,WWP2,ASB1,PDIA3,DRG1,ASB7,DCAF11,CSTA,SKIC8,PCNA,KLHL25,RBM3,TRIP4,COPS4,IMMP2L,FEM1C,KRAS,DCUN1D3,OTUD6B,CSNK1E,MOB3C,GHR,EZH2,ZC4H2,LRRC28,DIO2,TRIM44,MAD2L2,TSN,PCMTD1,PSMD6,STAT2,MCM3,RNF40,CUL3,CUL2,COPS7A,MYC,RGMA,RIT1,OSGEP,COP1,PSMD14,YAF2,APPBP2,ASB3,MCMBP,CNPY3,PPP1CB,ASB8,ZER1,PIH1D1,FEM1A,RNF7 |
| 2.308e-04 | -8.37 | reactive nitrogen species metabolic process | biological process | GO:2001057 | 31 | 19 | 18204 | 5365 |
CYB5R3,NQO1,NOS1AP,DDAH1,TICAM1,CAV1,SPR,TLR2,AKT1,ACP5,MTARC2,CYP1B1,CYGB,ARG2,TLR6,PPARA,CYP1A1,TLR4,CYB5B |
| 2.308e-04 | -8.37 | MCM6 (minichromosome maintenance complex component 6) | protein interactions | 4175 | 268 | 102 | 19454 | 5460 |
VTA1,DUSP19,HUWE1,H3C1,KPNA2,H2AX,ACTR1A,TP53,ILF2,PPP4C,GINS4,RB1,H2AZ1,CD274,MIF,TOP1,MAPRE2,COPS5,SUV39H1,USP15,H2AC4,MTDH,BAP1,RHOU,SOD1,ORC6,RPA3,SIRT7,NUCKS1,SMC4,FBXW7,GTF3C4,CDC42,CFTR,SF3A1,TPT1,FAM161A,ING5,CCND1,UBE2M,ACACA,RPA2,LMNA,METTL14,GANAB,TRIM24,CCNF,VIRMA,DEPDC1B,GMNN,TNFAIP3,MAPRE1,UBE2H,STK24,IVNS1ABP,UBE3A,MCM6,SSRP1,PSMA1,FGD2,KRAS,ASF1A,E2F4,MOB3C,STK16,TAF10,EZH2,H2BC1,PHB1,HSP90AB1,RHOH,HMGA1,IFI16,HSPB1,HDAC5,SF3B1,PSMA3,EP300,NUDT2,MCMBP,STAU1,RND2,DUSP22,ARCN1,CDC7,PRMT5,LMBR1L,SCNM1,USP38,SNRPB2,MATR3,MCM3,MCM4,BAG3,MYC,CUL3,H1-1,RIT1,POLR1B,MCM8,BRCA1,LMNB1 |
| 2.311e-04 | -8.37 | STK11IP (serine/threonine kinase 11 interacting protein) | protein interactions | 114790 | 81 | 38 | 19454 | 5460 |
EGLN3,TLR1,FMOD,RAC2,BRD9,SRP14,STK11,THTPA,LAMTOR1,RHOG,SMAD4,FBXW11,RHOB,TLR9,SMARCE1,LAMP3,BCL7C,LAMP2,CUL3,STX7,SS18,HSCB,CDK20,TLR2,RAB9A,NUBP2,RHOU,TLR4,SMARCD3,TMEM106B,SMARCB1,RPA2,CDC42,MGARP,RND2,ATG16L1,TOP3B,COMTD1 |
| 2.311e-04 | -8.37 | SPRY4 (sprouty RTK signaling antagonist 4) | protein interactions | 81848 | 81 | 38 | 19454 | 5460 |
RHOB,LAMTOR1,RHOG,STYK1,CBL,TESK1,RAB5C,RAB11A,DPP4,LAMP2,RAB2A,ORMDL3,LAMP3,RHOJ,RHOH,ARF6,CAV1,LMAN1,STX6,HRAS,RAB35,GJA1,RAB4A,TFRC,STK16,BET1,RAF1,CDC42,RAB3B,KRAS,ZDHHC17,STX7,TSPAN15,GARRE1,RHOU,NTRK2,RAB5A,RAB9A |
| 2.319e-04 | -8.37 | CXCL12 (C-X-C motif chemokine ligand 12) | protein interactions | 6387 | 37 | 21 | 19454 | 5460 |
CD4,PDIA6,CXCL14,CXCR4,CXCL10,ITGAV,PTP4A3,CXCL9,HMGB1,CXCL11,CCL28,FBXO7,CCL11,DDX39A,CCL5,CCL20,XCL1,CXCL12,DPP4,CCL21,CCL25 |
| 2.319e-04 | -8.37 | CD46 (CD46 molecule) | protein interactions | 4179 | 37 | 21 | 19454 | 5460 |
CD9,RHOG,CD46,MGAT5B,NONO,CD81,PYCR1,SRC,CSTF3,GPR37L1,LAMTOR3,YES1,VTI1B,CD151,ANKRD46,KRAS,MSN,ITGA2,DLG4,GNA11,LMBR1L |
| 2.334e-04 | -8.36 | BCCIP (BRCA2 and CDKN1A interacting protein) | protein interactions | 56647 | 140 | 59 | 19454 | 5460 |
DNAJB6,SORD,RIT1,CHORDC1,LMNB1,BICD2,TENT2,RPL10,RPL19,ESR2,SRC,LDHA,TENT5C,ACTB,GSK3A,CSNK2B,TRIM27,SNRPD1,RPA2,LMNA,ABCB1,LDHAL6B,LSM2,CDC42,CDKN1A,BET1,TPT1,CAPN1,PTN,RPL4,MTDH,EP300,TCEA1,RPA3,RPL23,YWHAB,DDRGK1,PDIA3,DKC1,EGLN3,NOP9,SPPL3,THOC1,MRPS9,ZRANB2,CAPN2,CDK8,MAP1LC3B,FCF1,TULP3,MARCKSL1,RAF1,TP53,PSMB10,H3C1,G3BP1,CSE1L,HNRNPK,UBE3A |
| 2.343e-04 | -8.36 | O-methyltransferase activity | molecular function | GO:0008171 | 22 | 15 | 18094 | 5411 |
MRM2,COMT,CMTR1,ARMT1,PCMTD1,CMTR2,LCMT1,FTSJ1,PCMTD2,HENMT1,COMTD1,ASMT,TRMT13,FTSJ3,MEPCE |
| 2.352e-04 | -8.35 | RNF144A (ring finger protein 144A) | protein interactions | 9781 | 92 | 42 | 19454 | 5460 |
NPC2,UBE2L3,UBE2V2,TMPO,PTP4A3,CAND1,HNRNPL,RPS9,SGTA,MFSD5,CALML5,ADD1,PSMB5,CD274,RAB35,UBE2H,RPL10A,COL1A2,EPHA2,UBE2D1,RAP2C,PRDX1,CSK,PIK3R1,RPL17,CTNND1,RPS4X,CSE1L,PIK3R2,UBE2K,SLC7A1,YIF1A,DLG1,NAE1,CASK,HSP90B1,TMEM31,EEF2,UBE2V1,PPP1CB,SEC22A,E2F4 |
| 2.352e-04 | -8.35 | ITPA (inosine triphosphatase) | protein interactions | 3704 | 92 | 42 | 19454 | 5460 |
HNRNPA1,GALE,GLO1,USP14,MOV10,PGAM1,FKBP1B,SERPINB1,UBE2H,HSPB1,TES,CCNF,QNG1,RAB35,ENO1,KLK3,NUP35,APEX1,UMPS,AASDHPPT,TSHR,UBE2V1,UBLCP1,GGCT,RAF1,SHMT1,TOR1AIP2,CCR1,VPS4B,MMP28,SERPINB11,PSMG4,PPIH,HNRNPA2B1,EXD2,FKBP2,OLA1,GRPEL1,IMPA2,SERPINB6,NSFL1C,SSNA1 |
| 2.352e-04 | -8.35 | TOPORS (TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase) | protein interactions | 10210 | 92 | 42 | 19454 | 5460 |
RB1CC1,BRD3,SPOP,UBE2D1,UBE2E3,HNRNPA1,NONO,ATG9A,CREBBP,ZCCHC10,DHX15,HNRNPL,TOP1,SUMO2,RBBP4,NKAP,GSK3A,CSNK2B,UBE2I,SIN3A,NKX3-1,UBE2N,TOPORS,EEF1A1,H2AX,RPL15,ZNF263,UBE2W,TP53,SUMO1,SAP18,PSMC1,SRSF4,RPL17,GTF2I,RBBP7,UBE2D3,SATB1,SF3B1,MTDH,SNIP1,PML |
| 2.352e-04 | -8.35 | APRT (adenine phosphoribosyltransferase) | protein interactions | 353 | 92 | 42 | 19454 | 5460 |
CCNF,SNX12,NUDT9,LDHA,DYNC1I2,TUBB,SUMO2,UMPS,EGLN3,CAV1,ESR2,VIRMA,DPP4,RAB2A,LDHB,ADIPOR2,RPL6,AR,GMPS,AGR2,RPL23,BAP1,SOD1,MYD88,RPA3,KLHL24,SQSTM1,EMC2,HSCB,DUSP21,PSMB10,LYPLA2,LYPLA1,TOP3B,RAF1,INSIG2,DUSP1,DUSP22,JUP,RPA2,LMNA,CHMP4C |
| 2.353e-04 | -8.35 | RABGAP1L (RAB GTPase activating protein 1 like) | protein interactions | 9910 | 120 | 52 | 19454 | 5460 |
VIRMA,JUNB,RPS12,PHF21A,CCHCR1,HOXC4,RFTN2,LIN7B,SFN,RAB11A,MLF1,CSK,STX7,OIP5,SGF29,KDM1A,RAB9A,LIN7C,HELLS,HEXIM1,GIT2,GOLGA5,JUP,RPA2,RSAD2,NUF2,HMG20A,RB1,CYB5A,MAP1LC3A,RPRD1A,RAB35,EXOC1,YWHAH,LAMP3,DLK2,INSYN1,YWHAG,IFI16,RIGI,ZNF365,LSM4,TRIM11,RAB13,TFPT,UQCC2,CASK,RAB4A,VPS33A,GABARAPL1,ARFGAP1,MAX |
| 2.353e-04 | -8.35 | CLPTM1 (CLPTM1 regulator of GABA type A receptor forward trafficking) | protein interactions | 1209 | 120 | 52 | 19454 | 5460 |
TP53,CCDC47,ISG15,SFTPC,EZH2,STIM1,RPN1,NCR3,CCR1,RBPJ,TMT1A,LRRN4CL,RIGI,CFC1,FAM241A,HM13,COPS5,CCR6,RB1CC1,ELSPBP1,HSD17B11,ASIC1,DNAJC1,DNAJB9,LMAN1,CD1A,CFTR,TMEM106A,OTULINL,SEC62,SSR1,UBAC2,FGFR1,RPA2,TMEM106B,RPA3,DERL1,HSPA8,SYVN1,PGK1,HSCB,CCR4,COIL,GPR17,GGH,SDF2L1,GXYLT1,CCNF,LMBR1L,SEC61B,CCR2,VIRMA |
| 2.361e-04 | -8.35 | RAB23 (RAB23, member RAS oncogene family) | protein interactions | 51715 | 52 | 27 | 19454 | 5460 |
RHOJ,ARF6,NUP35,CAV1,DIRAS3,HRAS,RAC2,PLPPR1,HSD17B11,GJA1,TRIM23,RHOB,LAMTOR1,RHOG,RAB11A,RAB5C,LAMP2,RAB2A,CREB3,LAMP3,KRAS,AKAP1,GDI2,ZER1,ARFGAP1,CDC42,OTULINL |
| 2.363e-04 | -8.35 | CDCA2 (cell division cycle associated 2) | protein interactions | 157313 | 65 | 32 | 19454 | 5460 |
IER2,CBX3,LMNA,CDK1,NUP153,PPP2R1A,PPP1CB,ASF1A,KPNA2,B2M,H3C1,NUP50,EWSR1,BRCA1,LMNB1,KPNA1,PPP2R5A,CUL3,MYC,GAPDH,AR,PPP1CC,YWHAG,H2BC9,YWHAH,SNRNP40,TCEAL1,APEX1,VIRMA,KLF9,RAN,ZNF330 |
| 2.372e-04 | -8.35 | serous | COSMIC cancer mutations | serous | 34 | 20 | 16828 | 4835 |
SMAD4,HRAS,KRAS,PIK3R1,IDH1,PIK3CA,FGFR1,DICER1,PTEN,BRCA1,TP53,KIT,MET,RB1,CTNNB1,PPP2R1A,IDH2,FBXW7,JAK2,AKT1 |
| 2.375e-04 | -8.35 | Toll-like receptor binding | molecular function | GO:0035325 | 14 | 11 | 18094 | 5411 |
TLR2,CD36,LY96,TOLLIP,TIRAP,SYK,S100A8,TLR6,TLR10,TLR1,MYD88 |
| 2.376e-04 | -8.34 | NTRK3 (neurotrophic receptor tyrosine kinase 3) | protein interactions | 4916 | 367 | 134 | 19454 | 5460 |
ENO2,MAD2L1,MB21D2,NDFIP1,DYNLL1,TIMP1,GGH,RPS29,VEZT,NIBAN2,PKP4,SFN,EPS8,SCFD1,HSP90AA1,SERPINH1,BEX3,MYO6,HADHA,CXCR4,DNAJC3,TBC1D24,TMEM106B,TIMP3,GNB4,CYFIP2,CNPY3,ETF1,USP6NL,NOTCH2,ARCN1,SLC25A3,VAPB,STX5,PTK7,TNIK,WDR6,ERLIN1,OCRL,COCH,OSBP,XPO1,DDRGK1,CTNNB1,QPCTL,PIK3R1,HAX1,RPL23,CDK5RAP3,NCK1,SLC39A7,MYO1B,PDIA6,SLC25A5,NDUFA4,AHCYL1,TFG,JUN,HTR2A,NEU1,HGS,RPN1,NUDT19,STIM1,PRKAG1,SEC61A1,EPCAM,CDIPT,GAB1,CTNNA1,FERMT2,SH3BP4,TECR,COPE,GORASP2,PTPN11,XPOT,EPHA2,ATP1B3,SDF2L1,DNAJC10,ARFGAP3,SQSTM1,LIN7C,TEX264,MAIP1,BANF1,ITM2B,CLU,HSPA5,YKT6,NF2,PIK3R2,NTPCR,ARHGAP1,MET,CDK1,JUP,PICALM,HSP90B1,SEC23A,CDCA3,HACD3,SRPRA,HRAS,PTPN1,DOK6,STT3A,ACSL4,EHBP1,UBE2N,ILVBL,TMED9,RPS27L,FCHO2,HM13,NFKB1,OSBPL8,TMEM11,ESYT1,SHC1,NOS1AP,NTRK2,EHD4,DLG1,CTNND1,ARF4,RIGI,SRPRB,CCDC47,SNAP29,DOK5,TFRC,ADAMTS1 |
| 2.380e-04 | -8.34 | TLR9 (toll like receptor 9) | protein interactions | 54106 | 73 | 35 | 19454 | 5460 |
TMPO,SRC,TLR1,GSK3A,STUB1,HRAS,GUCY1B1,SNX14,PSMD14,TRAF6,NFYA,SMARCA5,TNFAIP3,IFI16,HSPA5,UNC45A,KDM1A,RNF115,GTF2I,MCMBP,TOLLIP,BSCL2,RAB13,HSPA8,LRRC3,MTDH,ABCB9,RAB1A,MYD88,ADCY3,PAK2,CNPY3,DIPK1A,SYK,TBK1 |
| 2.380e-04 | -8.34 | AKR1B1 (aldo-keto reductase family 1 member B) | protein interactions | 231 | 73 | 35 | 19454 | 5460 |
TXNRD2,PGAM1,GLO1,CFL2,YWHAZ,NME2,SORD,OAT,ENO1,ENO2,TFE3,FABP5,MSN,HEBP1,NDN,APLNR,FABP7,SMAD1,CDC42,CHMP4C,LMNA,RPA2,AKR1A1,SOD1,RPA3,INPPL1,BAP1,GPX4,HSD17B10,PRDX6,HINT1,PGK1,NMRAL1,HSPE1,PMP2 |
| 2.380e-04 | -8.34 | TRAIP (TRAF interacting protein) | protein interactions | 10293 | 73 | 35 | 19454 | 5460 |
MCMBP,UBE2K,KRAS,UBE2D3,RFC3,RFC2,RAD21,RNF20,MCM6,RFC4,PCNA,RPA2,LXN,TP53,TBK1,SYK,FEN1,TRAF2,H2AX,MAPRE2,TOP1,TRAF1,CEP19,TNFRSF1B,TSG101,TRAF6,TRIM23,NME2,UBE2D1,UBE2H,USP2,MCM4,MCM3,RNF40,RFC5 |
| 2.395e-04 | -8.34 | GPM6A (glycoprotein M6A) | protein interactions | 2823 | 143 | 60 | 19454 | 5460 |
FITM2,RAB3A,HAX1,STX1A,CDH13,P2RY1,NR2F6,SNAP91,DUOXA2,MAPRE2,PRNP,DERL2,SNAP25,ARMC1,GNAQ,TSPAN3,CPE,GNAZ,RAB6B,PPID,HPCAL1,KIF2A,YIPF3,COMTD1,FKRP,TMED7,L1CAM,SYN3,CAMKV,VPS26B,TSPAN17,CRMP1,SYP,HMGCS1,HPCA,CYRIA,RABIF,VKORC1L1,RAB14,RAB3C,ODR4,MACROH2A1,GNAO1,RMDN3,SCAMP2,CYRIB,MACROH2A2,PRKCA,STXBP1,NCALD,ATP6V1C1,PXMP2,ZDHHC17,OGDHL,YKT6,CNTN1,NAPG,TRIM3,GRIA2,CCDC126 |
| 2.395e-04 | -8.34 | DCAF8 (DDB1 and CUL4 associated factor 8) | protein interactions | 50717 | 143 | 60 | 19454 | 5460 |
CD9,SMAD4,KPNA1,DCAF11,MDFI,CALR,SUV39H1,COPS5,XPO1,TCP1,PRNP,DNAJC1,HNRNPL,CCT7,MDM2,EGLN3,PTPN1,COPS2,PNMA2,CCT5,RAF1,THAP1,MAP2K3,BACH1,COPS4,PAK6,RPL31,BAG2,PCNA,FBXW11,DCAF16,CCT2,UBE2H,PIK3R3,PDE7A,GSTK1,COPS7A,MYC,MLF2,GGH,TRIM54,CAVIN2,ESR2,SFRP4,RAN,CCNF,SEC61B,GSK3A,PRMT5,STOX2,CSNK2B,TFB1M,UBE2M,CCND1,WDR77,RPS15,BAP1,HELLS,RNF113A,TWNK |
| 2.395e-04 | -8.34 | GABARAPL1 (GABA type A receptor associated protein like 1) | protein interactions | 23710 | 143 | 60 | 19454 | 5460 |
TRIM21,BSCL2,PIK3CG,NEK9,RETREG1,RIGI,ATG4A,AZI2,STBD1,ARFGAP1,VDR,DISC1,MAP1LC3A,BRD9,PSMB4,GYS1,STK3,HSP90AB1,RAB11B,PRNP,HYPK,TP53INP1,ATG7,XPO1,WDR11,TBC1D5,MOV10,KXD1,RB1CC1,OPRK1,SQSTM1,HADHA,TMEM160,DVL2,TEX264,GABARAP,ATG4C,BNIP3L,FUNDC1,SEC62,GABARAPL2,FTH1,TBC1D17,HBB,RETREG3,OPTN,KBTBD6,SRPK2,APEX1,TAX1BP1,DYNLL1,THAP7,TBC1D1,TRIM32,CUL3,TBC1D25,HSP90AA1,CCT2,TBC1D16,ATG3 |
| 2.400e-04 | -8.33 | G2/M Checkpoints | REACTOME pathways | R-HSA-69481 | 169 | 75 | 10285 | 3229 |
PSMC4,ORC5,PSMA3,PSMB5,RMI1,YWHAB,PSMB1,RFC2,PSMD3,PSMB7,H2BC11,PSMB3,RPA2,H2BC14,MCM6,PSMB6,PSMA2,RNF8,RMI2,PSMC5,PSMB11,SFN,PSMA5,PSMB10,H2BC17,MCM4,PSMA4,PSMD7,H2BC12,YWHAZ,CDK1,PSME1,PSMD10,UBB,YWHAH,UBA52,MDC1,PSMD14,CCNB1,PSMD12,PSMC1,UBE2N,BABAM1,TOPBP1,MCM8,PSMA6,SUMO1,PSMB2,PSMD1,UBE2V2,H2AX,CDC7,YWHAG,RFC3,PSMB9,BRCA1,NBN,SEM1,RFC5,PSMD6,PSMB4,ORC6,RPA3,PSME2,RAD1,PSMD4,MCM3,RBBP8,RFC4,H2BC9,RPS27A,H2BC1,PSMA1,TP53,PSMC3 |
| 2.406e-04 | -8.33 | IRF_2 | prosite domains | PS51507 | 9 | 8 | 12186 | 3388 |
IRF2,IRF3,IRF4,IRF1,IRF6,IRF9,IRF7,IRF8 |
| 2.406e-04 | -8.33 | IRF_1 | prosite domains | PS00601 | 9 | 8 | 12186 | 3388 |
IRF6,IRF9,IRF2,IRF3,IRF4,IRF1,IRF8,IRF7 |
| 2.407e-04 | -8.33 | CORO1B (coronin 1B) | protein interactions | 57175 | 184 | 74 | 19454 | 5460 |
CTNNB1,KARS1,VPS26A,PPP3CA,CORO1C,TES,CYB5A,RPL9,HACD3,SWAP70,OSBP,TRIM15,OTUD6B,MAP1LC3B,SOX2,KBTBD4,TOP3B,RAF1,MTCH2,E2F4,ZRANB2,RAD23B,IFT57,CAPZA2,ACTR2,RUVBL2,ZYX,ATF3,SRSF12,GJB1,NUP107,G3BP1,TRIM37,KPNA2,BTF3,USP14,MYC,COPS7A,NDUFB10,PAPOLA,CRMP1,VMP1,BICD2,PHKB,CTTN,SH3BGRL,ESR2,USP5,THAP8,SSH3,ATP5F1B,NDN,ACTB,SEC62,PPP1CB,ETF1,NFYB,PRKCA,RARS1,EIF4B,TBC1D17,CSNK1A1,RPA2,FGFR1,LSM2,NMRAL1,TXNL1,ARPC2,SQSTM1,DLAT,CORO6,BAP1,RNF41,NAPG |
| 2.419e-04 | -8.33 | CWC22 (CWC22 spliceosome associated protein homolog) | protein interactions | 57703 | 106 | 47 | 19454 | 5460 |
NUPR1,MOB3C,PDHA1,NFKBIL1,SIGLECL1,EXOSC8,CTDSP2,CD2BP2,TSSC4,CAMKV,KRAS,G3BP1,SRSF7,SNIP1,PDAP1,DDX23,DDRGK1,YWHAH,YWHAG,PRPF19,CDC5L,VTI1B,BRD9,EED,USE1,MED23,CFTR,DENND2D,SEC62,ATG16L1,SYVN1,NKAPD1,RPA3,SNRPA,UBE2H,PDCD4,HNRNPC,MYC,ESR2,RPL22,SNRNP40,PSMD4,FGFBP1,SYT2,EIF4A3,DOK4,S100A6 |
| 2.421e-04 | -8.33 | ZNF638 (zinc finger protein 638) | protein interactions | 27332 | 247 | 95 | 19454 | 5460 |
TFPT,SRSF12,RPL17,H3C1,WASL,APOBEC3D,MAP1LC3B,KIF1C,JPH4,STARD13,ARL4D,SSU72,EIF4E2,CDK9,CDC5L,KCTD3,CAND1,TOP1,E4F1,EDC3,SPP1,SNRNP70,H2AC4,TIAM1,PRKCB,FAM53C,RPA3,SIRT7,EIF4E,RPL4,GTF3C4,SIPA1L1,ATG16L1,AGAP1,RPA2,WWP1,FGFBP1,RPS3,CCNF,SH3BP4,VIRMA,SRPK2,RNASEH1,DEPDC1B,PPP1CC,FAM110B,TBC1D25,EWSR1,SRSF7,TESK2,PLSCR1,MRPS17,SRSF4,SSRP1,G3BP1,CHCHD2,SOX2,LGR4,EZH2,EED,FEZ1,NUP35,HNRNPL,SUMO2,CCAR2,HNRNPA1,YWHAG,YWHAH,DDX50,IFI16,WWP2,MED4,YWHAB,ANKRD50,CAMSAP2,DDX23,HSPA8,SNRPA,RTKN,PSMC1,PPP1CB,INPP5E,RPS9,APEX1,TNPO3,RPL10,MATR3,MAP3K21,ZNF668,SNRPB,CCDC85B,MYC,SFN,YWHAZ,MYO6 |
| 2.425e-04 | -8.32 | KLF5 (KLF transcription factor 5) | protein interactions | 688 | 187 | 75 | 19454 | 5460 |
MID1IP1,ATXN1L,PHF12,GTF2F2,UBE2I,PTEN,TRIM24,QSER1,PRMT5,RPL37A,GSK3A,ZBTB17,ESR2,PRRC2A,MORC4,NOP16,CREBBP,PSMB2,AR,LDB1,SMARCE1,RPL39,RPS17,RPS5,SMAD2,BAP1,EP300,NOP53,FBXW7,RPS15,GTF2I,CLU,SS18,SUMO1,WDR77,WWP1,JUP,PPARG,PRKCA,RPL26L1,ACTA2,FUBP3,PHB1,TFE3,GTF2B,SMAD3,CEBPG,CCAR2,EGLN3,USP3,TLE1,NFKB1,CTNNB1,XPO1,SMAD4,FOXP1,AKAP8L,NKRF,LSM14A,BCL7B,BCL9,MRPS18B,G3BP1,ZNF609,PSMA2,ANP32B,FOXP4,POLDIP3,TP53,ZMYM4,GTF2E2,JUN,RBM34,ILF2,RPS11 |
| 2.425e-04 | -8.32 | UTP23 (UTP23 small subunit processome component) | protein interactions | 84294 | 187 | 75 | 19454 | 5460 |
RPL10,SRPK2,RPL19,ESR2,RPL13A,RPL35,TRIM27,RPL37A,PRKRA,MRPS28,FGFBP1,H1-1,NSA2,RRP7A,RIT1,RPS5,TRIM23,RHOB,FTSJ3,ZCRB1,MECP2,ZSCAN25,SMARCA5,MYC,MRPS7,BRIX1,NHP2,RPL4,STAU1,DGCR8,SQSTM1,SF3B1,RPS28,RPL26L1,RPLP0,H1-5,SURF6,DKC1,LYAR,SNRPA1,RPL7,RPS10,RPLP2,HP1BP3,PRR3,KRR1,RPL8,PDE9A,RPS2,H2AC4,ZCCHC9,RPL6,CMSS1,BAZ1B,RPS13,SRSF12,MRPS18C,MEPCE,KRAS,H1-6,HUWE1,PAK1IP1,TRIM26,DHX9,RPL3,RPL31,RPL18,RBM34,GLE1,FCF1,MAK16,H1-3,TRAF2,RPSA,STRBP |
| 2.437e-04 | -8.32 | TPD52L1 (TPD52 like 1) | protein interactions | 7164 | 42 | 23 | 19454 | 5460 |
GSKIP,PAK6,UCHL3,NPM3,GABBR1,BAP1,TPD52L1,PSMC3,AZIN2,KCTD12,EIF3J,TXNL4A,TPD52,DAPK1,TNFRSF1B,YWHAB,YAE1,LAMTOR1,YWHAZ,RNF40,YWHAG,YWHAH,ISYNA1 |
| 2.440e-04 | -8.32 | TRIM38 (tripartite motif containing 38) | protein interactions | 10475 | 47 | 25 | 19454 | 5460 |
TSPYL4,UBE2I,UBE2E3,TRAF6,SLC2A1,UBE2D1,GORASP2,RFC5,PSMA4,UBE2E2,CUL3,HSPA5,IFNG,TICAM1,FBXW7,UBE2D3,EIF1B,HSPA8,TCEA2,TAB2,NLRP6,SDCBP,STXBP1,AZI2,DDX39A |
| 2.440e-04 | -8.32 | SARM1 (sterile alpha and TIR motif containing 1) | protein interactions | 23098 | 47 | 25 | 19454 | 5460 |
LMBR1L,CCNF,CDIPT,STT3A,CHRM4,CAV3,KDSR,NRP1,TRAF6,POC1B,AKAP1,PIK3AP1,MYD88,RPA3,TICAM2,TOMM20,NPTN,SEMA4C,HCST,TRAF2,CCDC47,MTCH2,RPA2,GHITM,PPT1 |
| 2.440e-04 | -8.32 | RMND1 (required for meiotic nuclear division 1 homolog) | protein interactions | 55005 | 190 | 76 | 19454 | 5460 |
ESR2,NDUFAF4,CHCHD3,FBXO22,CTSB,RETREG3,MRPS28,DLST,TACO1,S1PR4,RIC3,MRPS25,MRPS16,GLT8D2,HSD17B3,PYCR2,PYCR1,GPR17,NDUFB10,ST3GAL1,COX6B1,POLDIP2,MRPS7,GPC1,LPAR1,HSCB,NDUFS2,HADHA,TMEM106B,SLC39A9,NDUFA5,SAMM50,MRPS34,P2RY12,COX6C,NDUFAF3,MRPL12,LEAP2,MTX2,TIMMDC1,CHST7,PLGRKT,MRPS23,NDUFS8,DNAJC1,PHB1,COX4I1,OCIAD2,AIFM1,MRPS9,ST3GAL4,LY6G5C,MRPS26,DDRGK1,CCR6,MRPS35,COX5A,STOML2,CLPX,GALNT2,MRPS17,ETFA,ATP5F1D,SRPRB,MRPS18B,LPAR2,CLPB,NDUFA4,CRELD1,NDUFA12,NDUFS6,NDUFS3,DDX39A,PPIF,ETFB,HSDL2 |
| 2.445e-04 | -8.32 | LRIF1 (ligand dependent nuclear receptor interacting factor 1) | protein interactions | 55791 | 241 | 93 | 19454 | 5460 |
MAD2L1BP,DDX42,CHAMP1,CBX3,PSMC3,SERPINB9,MVD,RRM1,IKZF5,TAF1D,HSPE1,H3C1,MNAT1,SMN1,PQBP1,RAB27A,SMCHD1,ZNF24,CALR,ATP1B1,CRADD,GPRASP2,VPS26C,PRNP,OLFM2,RAP1B,RPA2,E2F6,SNRPN,CDC42,HMGB1,RPA3,PPM1G,CCDC106,MIS12,NCKIPSD,EMILIN1,HMOX2,NTAQ1,PNP,PDCD5,PAFAH1B3,PSPC1,MOB4,AZIN2,CPE,POLR2C,CBLN4,ELF1,ASF1A,PAEP,PCGF6,PFDN1,GADD45A,ATF3,CDKN2C,FOSL2,HSPB1,MPHOSPH6,RHOH,POLR3F,RBM5,FEZ1,RPLP1,SPINT2,STX5,CETN3,S100A8,ADNP,KLF3,PPARG,ANXA7,CDKN1A,SUPT4H1,PHB2,DCTN3,RNF10,COX17,SAT1,FAS,RIT1,DSN1,MYC,BRMS1,RFC5,UBE2V2,LRIF1,GADD45G,GSTM4,CBX5,DDIT4,POLR2F,RPL37A |
| 2.446e-04 | -8.32 | SLC38A1 (solute carrier family 38 member 1) | protein interactions | 81539 | 123 | 53 | 19454 | 5460 |
ARF6,RHOH,DIRAS3,LMAN1,STX6,CAV1,RPRM,RAB35,HRAS,SSMEM1,GJA1,RAC2,RHOG,STYK1,ATG9A,LAMP2,PMP22,RAB5C,LAMP3,SCGB1D1,FATE1,TMEM60,KRAS,RAB3B,FLOT1,ATP5PF,COX8A,TFRC,RAB4A,RND3,TP53,RHOJ,ARF1,AMIGO1,LAMTOR1,RHOB,CREB3,RAB2A,CSK,SCN3B,VAMP5,PTPN11,RAB11A,STAU1,STX7,RHOU,RAB5A,RAB9A,GRM2,ARL15,PDCD1LG2,RND2,CDC42 |
| 2.446e-04 | -8.32 | RAB6A (RAB6A, member RAS oncogene family) | protein interactions | 5870 | 123 | 53 | 19454 | 5460 |
HEXIM1,RPA2,TOMM22,BET1,PXMP2,RNF11,RABAC1,PMAIP1,RAB5A,AKAP1,SQSTM1,RAB9A,RPA3,PEBP1,NRP1,BICD2,H2BC9,RAB2A,C9orf72,RAB11A,MAD2L2,RPGRIP1L,ARF1,LMBR1L,CYB5R3,FURIN,EZH2,GDI2,RAB6B,SOX2,RAF1,FKBP2,RNF26,KRAS,ETFA,TGFBR2,RAB3B,SRPRB,RABGGTB,RAB1A,TMT1A,HAX1,AGR2,TIAM1,LAMP3,DPP4,LAMP2,RAB5C,RAB11B,FZR1,RAB1B,OCRL,HRAS |
| 2.446e-04 | -8.32 | TWNK (twinkle mtDNA helicase) | protein interactions | 56652 | 123 | 53 | 19454 | 5460 |
APOBEC3C,HEXIM1,MTRES1,NCOA5,PABPC5,HSCB,FBXW7,RPL4,HMGB1,NGRN,EXD2,SPECC1L,SQSTM1,GFM1,MECP2,SP1,DNAJC19,AUH,MTG2,HNRNPC,PMPCA,BTF3,TUFM,ESR2,SRPK2,TACO1,TRIM27,PDHA1,PNMA2,GFM2,ZNF263,TOP3B,MRPL11,SOX2,METTL15,KRAS,B4GALT7,IMMP2L,HINT2,SRSF7,COX8A,RHOG,CHCHD1,MRPS26,RB1CC1,SMAD9,MAP4,FOXP1,MTRF1,YWHAH,TRA2A,SSBP1,GATD3 |
| 2.452e-04 | -8.31 | RNF7 (ring finger protein 7) | protein interactions | 9616 | 146 | 61 | 19454 | 5460 |
RNF7,UBE2F,UBE2M,ASB8,WSB1,UBE2D3,ASB3,UGDH,PMAIP1,HSPA8,PLA2G15,PDF,CUL2,CUL3,TBCE,CREBBP,MAT2A,SOCS5,ACTB,TRIM46,PCMTD1,UBA3,UBE2L3,UBE2S,METAP2,APOBEC3G,CSNK2B,SPSB3,PCMTD2,DCUN1D5,RBPJ,GHR,GNB1L,CSNK1E,DCUN1D3,SOCS3,HNRNPF,MNAT1,SOCS2,PABPC1,SPSB1,HSD17B8,PSMD10,UBE2D1,MAP4,ASB7,ASB1,TRIM8,GSTM3,PRDX1,ELOC,APOBEC3F,CISH,CSNK2A1,FZR1,COPS7B,CAND1,ASB11,DHX15,CBFB,SOCS4 |
| 2.452e-04 | -8.31 | INTS3 (integrator complex subunit 3) | protein interactions | 65123 | 146 | 61 | 19454 | 5460 |
VIRMA,ESR2,POLR2B,RBBP4,POLR2F,INTS12,INTS10,GANAB,S1PR4,DNAJB6,CUL3,ZNF687,GPR17,AKT1,HMGB1,NUCKS1,RP2,HSPA8,RPA3,PIH1D1,MTRES1,HSP90B1,RPA2,CDK7,SSBP2,INTS6L,CDC5L,TOP1,SUMO2,POLR2I,HNRNPL,EED,NABP1,ST6GAL1,PPP2CB,EEF1AKMT3,SSBP1,LSM3,NAIF1,UBXN6,HMGA1,SSRP1,ZBTB14,ZNF592,KRAS,CPNE2,GLCE,ADORA3,POLR2G,POLR2C,POLR2D,CAPZA2,EZH2,SIGLECL1,FAF2,SOX2,LPAR6,RPAP2,PPP2R1A,SUPT5H,COMTD1 |
| 2.452e-04 | -8.31 | TBX5 (T-box transcription factor 5) | protein interactions | 6910 | 146 | 61 | 19454 | 5460 |
ZMYM4,ZMYM3,TP53,RBPJ,RPS11,MTA2,TAB2,LIMD2,SNRPE,RPS23,TUBB4B,DMAP1,EWSR1,SLC25A5,CCAR1,FBXO25,MSL2,SNRPG,POLDIP3,HNRNPF,VDAC1,KPNA2,HMGN4,PSMD3,ZNF24,OSBPL8,CTDSPL2,SIN3A,PSMB5,TMPO,CDC5L,NUP35,SNRPA1,NUP62,MED31,ACACA,VAPB,ADNP,HSPA8,TCEA1,DDX5,FXR2,KDM1A,ATP5F1A,MLF2,SMARCA5,PSMA4,PYCR1,COP1,CHTOP,PKNOX1,TRAF7,ZMYM2,PSMC5,RCBTB1,RTRAF,GTF2F1,ZBTB33,SCML2,TUBB,CHMP5 |
| 2.456e-04 | -8.31 | YTHDF3 (YTH N6-methyladenosine RNA binding protein F3) | protein interactions | 253943 | 238 | 92 | 19454 | 5460 |
LARP4B,HSPA8,AKAP1,RAB5A,SNRPA,ZDHHC17,G3BP2,B9D2,FXR2,STAU1,YTHDF1,SERPINB6,OST4,MYC,RAB11A,LSM14B,DCAF4,BRCA1,PRRC2A,RPL10,TAX1BP1,ISG15,TOP3B,RAF1,GLE1,NGB,ZC3H7A,RTCB,ZYX,LSM14A,PABPC1,PRPS1,G3BP1,CPEB1,XPO1,CNOT8,CNOT2,WWP2,DDX1,KRT8,PHB1,FUBP3,CEP19,NUP35,FAM98A,KCTD10,AGO1,RBMS2,CFTR,CDK7,RBFOX2,RPA2,LMNA,METTL14,LSM12,SMG5,RPA3,PML,RBM22,CEP85,IGF2BP1,NRP1,RC3H2,RTRAF,RPS20,CCNF,PSPC1,SMAP2,CTTN,IDE,VIRMA,CTSB,TNRC6C,TP53,KIF1C,YTHDF2,FURIN,TFRC,FAF1,SFXN1,GARRE1,CNOT6L,MEPCE,CNOT7,EDC3,MOV10,DPP4,GRSF1,SMG8,SNRNP70,SYNCRIP,FZR1 |
| 2.466e-04 | -8.31 | E2F1 (E2F transcription factor 1) | protein interactions | 1869 | 196 | 78 | 19454 | 5460 |
PHB1,SP2,RB1,GATAD1,MYBL2,TYMS,FZR1,MDM2,ERCC3,NFKB1,MOV10,TP53INP1,KDM2A,PKIB,DCAF5,TOPBP1,UBE3A,JAK1,RING1,ASF1A,IGF1,NSMCE3,ANAPC11,PCGF6,MNAT1,SP4,TP53,E2F4,GABPB1,EZH2,BIRC5,RNF126,UBN1,PHF12,CCNF,PTEN,MCPH1,RBBP4,STAT1,CEBPE,NDN,CBX5,MAD2L1,CDC20,PTPN11,NOP16,CUL2,CREBBP,MYC,AR,BRMS1,TADA3,PSMD14,BRCA1,DCAF4,TFDP2,SETD7,SP1,SERTAD2,NBN,PML,BAP1,HIRA,DDX5,EP300,BIRC2,KDM1A,SGF29,CCNA2,CDK7,CDKN1A,TRMT13,PRMT2,H2BC11,CDK1,CSNK1A1,MFAP1,E2F6 |
| 2.476e-04 | -8.30 | NUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1) | protein interactions | 64710 | 199 | 79 | 19454 | 5460 |
EWSR1,TOP2B,MCM6,MDC1,MSH6,H2AC6,RBBP7,PSMA1,HUWE1,KPNA2,EEF1A1,H1-3,ZMYM3,ZMYM4,MSX2,TBK1,MTA2,SMARCB1,EZH2,CHAMP1,CBX3,CHMP4C,EED,HP1BP3,DCK,COPS2,H2AZ1,RPL32,SRSF1,POLE3,MDM2,RBM42,HMG20A,AK5,SPTAN1,PRNP,CSNK2A1,BAZ1B,CDC26,POLB,HSPA8,EP300,RPA3,MME,BAP1,XRCC5,BANF1,AZGP1,PRCP,PRDX3,ING5,HEXIM1,MACROH2A2,CNDP2,RPA2,PHAX,MSN,TRIM24,MACROH2A1,ZNF22,RPS3,LIG3,UBB,CBX5,RPL22,TXN,RBBP4,SMARCE1,RFC5,DRAP1,USP14,SLC30A5,MCM4,SMARCA5,PYCR2,UBE2H,MECP2,CHRAC1,H1-10 |
| 2.490e-04 | -8.30 | ANKHD1 (ankyrin repeat and KH domain containing 1) | protein interactions | 54882 | 205 | 81 | 19454 | 5460 |
LARP4B,RPA2,RFXANK,FGF17,TXNL4A,RBFOX2,UTP23,HSPA5,FBXW7,STAU1,KDM1A,RNF113A,HSPA8,FOS,SIRT7,RPA3,BAP1,RBM23,HOXC4,FAS,OST4,CSK,MYC,VIRMA,DYRK1A,APEX1,SFRP4,TRIM24,ANAPC2,PHF21A,FGFBP1,PHAX,ATXN1L,EIF4A3,CRYBB3,S100A6,CCNF,OPTN,DISC1,SIX5,RPN1,TUBB4B,SKA3,TULP3,EXOSC8,SOX2,H2AX,TOP3B,RAF1,FBP1,ZNF263,EIF3E,AHCYL1,STX11,RUVBL1,RBBP7,BAG2,FHL3,KLF10,ZC3H7A,FGF3,USP15,TSNAX,H2AC4,FOSL2,CPEB1,UBXN6,MOV10,CNOT2,GSTM3,IRF9,KLF9,NUP35,AKAP17A,EGLN3,CAND1,NOB1,RPS16,MEAF6,RPLP1,EEF1AKMT3 |
| 2.490e-04 | -8.30 | SLC25A4 (solute carrier family 25 member 4) | protein interactions | 291 | 205 | 81 | 19454 | 5460 |
TNFSF8,VDAC1,MEPCE,GALNT2,IMMP2L,PAEP,FLOT1,MAP1B,OSTM1,SLC25A5,NDUFA4,ABCE1,LRRN4CL,COX8A,TUBB4B,TFCP2,EZH2,PPID,AQP3,SLC25A24,B3GNT2,UBL4A,RPSA,CTDSP2,MGARP,PPIF,APOO,FAF2,ARL6IP5,RAMP3,DUOXA2,SSBP1,STARD3NL,SLC2A1,RHOG,TMEM70,RPS2,MGMT,MOV10,EMC4,COPS5,DDRGK1,MAP3K14,NPTN,EMC1,GNB4,COIL,RPA3,VIPR1,RAB9A,SQSTM1,AKAP1,TIMM23,CTDSP1,RPA2,PPT1,HEXIM1,FBXO42,UQCRC1,PRDX3,GABRA1,CDK7,RPL10L,ACTB,PRKCE,APLNR,VIRMA,CCNF,CHRM4,NFKBIA,EDNRA,AP2M1,SLC1A1,BAX,NRP1,ICAM1,THTPA,UBE2H,RAB11A,ATP5F1A,AR |
| 2.492e-04 | -8.30 | KIF2A (kinesin family member 2A) | protein interactions | 3796 | 223 | 87 | 19454 | 5460 |
YWHAB,CAMSAP2,TRAF6,YWHAG,YWHAH,DDRGK1,STK4,MAP1S,WWP2,EGLN3,WDR44,SPTAN1,SUMO2,CSTPP1,SKA3,TUBB4B,NFKBIL1,PNMA2,SOX2,KIF2A,CSNK1E,BUD23,G3BP1,EWSR1,RUVBL2,TRIM11,SKA1,TRIP4,ILK,BRCA1,BTF3,MYC,LMO2,SFN,ESR2,MAD2L2,FBXO22,RMDN3,KLC2,LMO3,RPL27A,FXR2,NSFL1C,GPM6A,STAU1,TXNL1,EP300,MAP4,BRD3,TSNAX,SNRNP70,HDAC6,CD99L2,SLAIN2,RPL35A,CGAS,CEBPG,WDCP,CASK,NUPR1,EXOC3,UBL4A,TP53,RPS13,PSMA5,HAPSTR1,MAPRE1,UBE2H,PIP4K2C,TYW3,VIRMA,RPGRIP1L,MRPL53,CCNF,TUBA1B,PRKCA,RPL26L1,TRIM36,RPA2,GRM2,SLC35E1,GABRA1,SPTBN1,AATF,DVL2,RPA3,PRIM2 |
| 2.494e-04 | -8.30 | BCL2L1 (BCL2 like 1) | protein interactions | 598 | 208 | 82 | 19454 | 5460 |
UBE2I,AP2M1,GSK3A,ELOVL4,BAD,RPS3,VDAC2,UBB,ACTB,REEP4,TUBB,DYNLL1,TMOD3,PPP1CC,USP14,BFAR,TRIM32,AKT1,CREB3,BAX,RPS26,RIC3,GLOD4,RTN4,PMAIP1,PSEN2,BNIP3L,CLU,PTN,TPT1,CAPN1,SPTBN1,GSTP1,WWP1,CRYAB,JUP,CDK1,NLRP1,MCL1,ZHX1,RBM5,FABP5,RPL12,RPL8,CCT7,FUNDC2,SPTAN1,TOP1,G0S2,GAPDH,CTNNB1,TMBIM6,HNRNPA1,YWHAH,BAK1,TLE1,SIVA1,BCL2L1,HSPB1,RNF152,BECN1,TMEM50B,RAB1A,HSPD1,FKBP8,FLOT1,PSEN1,PDE2A,VDAC1,KRAS,EEF1A1,DDX39A,TMEM101,MTCH2,TP53,FBP1,RAF1,MIEF1,HGS,PLD3,VAC14,ACTR2 |
| 2.497e-04 | -8.30 | PTPRF (protein tyrosine phosphatase receptor type F) | protein interactions | 5792 | 211 | 83 | 19454 | 5460 |
TSPAN17,ABCE1,EFNB1,RNF133,SEMG2,LTBR,CD83,PPWD1,SEPHS1,KRAS,TGFBR2,ROCK2,EEF1A1,NUDCD3,TOP3B,TP53,RND3,IL20RB,IZUMO1,TUBB4B,ARPC3,PPFIA2,RNF128,PPFIA3,RAC2,RAB35,HRAS,CAV1,ARF6,RHOH,PIANP,CTNNB1,GAPDH,DPP4,RAB5C,DDX1,RHOG,HSPA8,RHOU,PML,CLDND1,RNF11,HSPA5,CLU,IL1RAP,EEF1G,GPC1,RND2,GPC4,CDC42,TMEM231,ATP6V0E1,GALNT1,RPA2,JUP,PICALM,SEC61B,ACAT1,CCNF,LMBR1L,SCN2B,TUBA1B,VIRMA,ESR2,LDHA,PTPRZ1,MANSC1,ACTB,RHOJ,ATP5F1A,DEPDC1B,UFD1,DNAJC5,NAA50,RAB2A,CREBBP,GFUS,LDHB,HSP90AA1,MARCHF3,CDKN2AIP,LAMTOR1,RHOB |
| 2.498e-04 | -8.29 | PLS3 (plastin 3) | protein interactions | 5358 | 217 | 85 | 19454 | 5460 |
KCTD10,TCP1,G6PD,CDK9,UBE2N,CD274,TYMS,DLGAP4,SHC1,FKBP4,DNAJC7,CBL,DDX1,PDIA3,IFI16,ELOC,HSPE1,HNRNPF,IMPA2,PSMD12,PABPC1,CCT8,PPP1R12A,FAF1,KLHL23,THG1L,RTCB,ABCE1,EWSR1,HAPSTR1,ERO1A,PSMC3,NUPR1,CCR1,RANBP1,TXNRD1,CCT5,INSIG2,RAF1,MSX2,PPP2R1A,ISG15,SOX2,SNX3,ACTB,PSMD6,TENT5C,ADRM1,TAGLN2,SNRPB2,DYRK1A,SH3BGRL,ENO2,CTNNA1,CCNF,MSN,GANAB,PSMD14,TXNIP,BICD2,UBE2H,SORD,RAB11A,CSK,UFD1,TUFM,USP14,STAU1,UFL1,HSPA5,MARS1,PIAS1,MAPKAPK3,BAP1,RPA3,SOD1,LCP1,HSPA8,FGFR1,FKBP14,PIH1D1,UBE2M,HEXIM1,EIF4B,CFTR |
| 2.498e-04 | -8.29 | MRPL23 (mitochondrial ribosomal protein L23) | protein interactions | 6150 | 214 | 84 | 19454 | 5460 |
NGRN,EXD2,GFM1,RPS15,MRPL17,EMC1,HSCB,MRPL40,MRPL57,MRPL41,MRPL20,ABCC2,MPV17,NDUFAB1,MRPL10,MRPL12,RBMS2,SMYD3,MRPS18A,ZNF574,MTRES1,RPS3,MRPL53,PNMA1,TACO1,MTG1,MRPL13,RPS20,FBXO22,RPL19,ESR2,RPL10,VIRMA,MYC,AUH,MTG2,HNRNPC,PMPCA,MRPL16,TUFM,FBXW11,RC3H2,MRPS25,HTRA2,RIT1,MRPL52,RPL23A,HINT2,HNRNPK,MRPL22,MEPCE,RPL17,MRPL11,ARFGEF1,E2F4,MRPL47,AURKAIP1,SOX2,METTL15,PDHA1,ILF2,MRPL33,MRPL51,MRPL49,SSBP1,RPL8,COQ8A,MRPS9,GATD3,MRPL50,MALSU1,MRPL24,MTRF1,GRSF1,MRPL9,SPP1,RHOG,MRPL18,SNRNP70,CHCHD1,TMEM70,MRPS26,RPS2,RPL23 |
| 2.506e-04 | -8.29 | TBC1D15 (TBC1 domain family member 15) | protein interactions | 64786 | 149 | 62 | 19454 | 5460 |
MEPCE,NEDD8,TOLLIP,LPAR2,HAPSTR1,LRTM2,STX12,MAP1LC3B,TMEM126A,COMTD1,E2F4,EGLN3,RPS16,VTI1B,TMED9,PRNP,SNX2,SPINT2,BRINP2,PTPN1,DNM2,CAMLG,EEF1AKMT3,DCAF11,ST3GAL4,XPO1,COPS5,RAB5C,VPS26A,GABARAP,HSCB,KDM1A,GCNT3,STAU1,VIPR1,AKAP1,RAB5A,ARFIP1,SQSTM1,RPA3,TBC1D17,UTP15,RPA2,UBAC2,CCNH,CFTR,ATP6V1C1,BET1,PLSCR4,IDE,TAX1BP1,PHF21A,OPTN,CCNF,S1PR4,LMBR1L,FIS1,UBE2H,PSMG3,CUL3,GPR17,CUL2 |
| 2.508e-04 | -8.29 | proton motive force-driven mitochondrial ATP synthesis | biological process | GO:0042776 | 55 | 29 | 18204 | 5365 |
ATP5MG,NDUFS2,STOML2,NDUFB4,ATP5PB,NDUFS3,ATP5PD,ATP5F1E,NDUFV2,ATP5F1B,NDUFB6,ATP5F1D,NDUFB5,ATP5PF,NDUFC2,NDUFS6,NDUFAB1,NDUFB10,ATP5F1A,SDHC,NDUFA1,NDUFS8,NDUFA2,NDUFB8,NDUFA5,NDUFB7,SDHB,ATP5PO,NDUFA12 |
| 2.508e-04 | -8.29 | negative regulation of viral genome replication | biological process | GO:0045071 | 55 | 29 | 18204 | 5365 |
SRPK2,IFNB1,TNF,CCL5,RNASEL,MAVS,BST2,APOBEC3B,RSAD2,OAS1,APOBEC3G,TRIM6,APOBEC3A,IFIH1,MORC2,SLPI,APOBEC3D,EIF2AK2,MX1,INPP5K,IFI16,APOBEC3F,ISG15,PROX1,APOBEC3C,PLSCR1,BANF1,APOBEC3H,ISG20 |
| 2.508e-04 | -8.29 | autophagosome maturation | biological process | GO:0097352 | 55 | 29 | 18204 | 5365 |
CHMP2A,TSG101,MCOLN1,GABARAPL1,SNAPIN,VMP1,LAMP2,MAP1LC3A,CHMP2B,VAMP7,VTI1B,VPS4A,VIPAS39,SNX14,CHMP1A,GABARAPL2,VPS33A,LIX1,VPS16,VAMP8,CHMP1B,CHMP5,MAP1LC3B,VPS4B,BECN1,GABARAP,SNAP29,STX17,CHMP4C |
| 2.513e-04 | -8.29 | MAP3K9 (mitogen-activated protein kinase kinase kinase 9) | protein interactions | 4293 | 30 | 18 | 19454 | 5460 |
MAGED2,AP2M1,SEPTIN7,WDR6,STUB1,VIRMA,SMURF1,DIRAS3,HPCAL1,MAP3K21,YWHAG,YWHAH,HPCA,YWHAB,DNAJB6,AP2A1,HSP90AA1,YWHAZ |
| 2.513e-04 | -8.29 | FBH1 (F-box DNA helicase 1) | protein interactions | 84893 | 30 | 18 | 19454 | 5460 |
MYC,RPA2,DTL,HSP90AA1,PIM2,SYNCRIP,RPA3,PCNA,PRR3,RPL13A,TTC9C,RALA,PTGES3,SKP1,APEX1,CCND3,RNF20,ZDHHC17 |
| 2.513e-04 | -8.29 | PRELID1 (PRELI domain containing 1) | protein interactions | 27166 | 30 | 18 | 19454 | 5460 |
CYRIB,NRSN1,VRK1,KRAS,STARD7,ADCK1,RIGI,PRELID1,FAM162A,STOML2,SYNGR2,NAA50,ACTL6B,CRTAP,CRYAB,ZMPSTE24,ACACA,RIT1 |
| 2.518e-04 | -8.29 | BID (BH3 interacting domain death agonist) | protein interactions | 637 | 95 | 43 | 19454 | 5460 |
ERG28,HINT1,HSD17B10,SQSTM1,RPA3,AHCYL1,MPST,RIGI,BCL2A1,CSNK1E,FASLG,DDIT4L,CAPN1,TPT1,SUMO1,MTCH2,CAPN2,CSNK1A1,RPA2,MCL1,CSNK2B,ZHX1,GATD3,MSN,BAD,CBX5,MBD5,CAV1,CDC5L,DDAH2,FCGR2A,CSNK2A1,ARL6IP6,GAPDH,BAG3,MOV10,BAK1,TLE1,CRMP1,BAX,YWHAB,BCL2L1,FAS |
| 2.520e-04 | -8.29 | CLDN7 (claudin 7) | protein interactions | 1366 | 84 | 39 | 19454 | 5460 |
ANKRD46,SYNE4,CXCL9,TMEM97,CNIH1,ITM2A,SERTM1,AIG1,RPRM,VAMP3,MFSD5,CYBC1,EPCAM,TMEM11,FXYD6,PLN,AQP2,FAXDC2,TMEM100,CYB561D2,VAMP5,SLC38A7,TMEM60,TNF,GPR37L1,LEPROTL1,JAGN1,TSPAN15,ERG28,EMP3,TMEM147,CTBP1,CYB5B,TOP3B,EDDM3B,BET1,PGAP2,SEC22B,UBIAD1 |
| 2.526e-04 | -8.28 | nucleobase-containing compound transport | biological process | GO:0015931 | 219 | 89 | 18204 | 5365 |
CETN3,CALHM3,SLC25A32,ALKBH5,SLC35E3,FYTTD1,ALYREF,RAN,GLE1,SLC25A51,SHOC2,BICD2,RBM15B,SLC35A2,SLC25A42,SMG5,TNKS,SLC35D1,XPOT,SLC35C1,SLC25A17,UPF3B,SRSF1,CHTOP,NXT1,HNRNPA2B1,NUP42,FLOT1,PARP11,LRRC8A,LRRC8B,SLC25A23,THOC2,HNRNPA1,NUP107,MX2,CD47,THOC6,G3BP2,PEG10,ABCC5,NCBP2,CETN2,SLC35A1,DDX39B,MAGOHB,PHAX,EIF4E,THOC1,RTRAF,FXR2,SLC35B4,SLC29A1,NUP153,CASC3,NUP50,TST,LRRC8C,TGFBR2,SLC35A5,SLC25A26,NUP62,SLC35B3,XPO5,MRPL18,DDX39A,IGF2BP1,TOMM20,ANKH,LRRC8D,NUP35,SLC25A5,SLC25A24,DHX9,SLC25A31,SRSF7,ZC3H11A,THOC3,XPO1,POLDIP3,RFTN2,ENY2,MAGOH,NXT2,SEC13,SLC25A4,EIF4A3,GJB1,NUP37 |
| 2.536e-04 | -8.28 | SLC12A4 (solute carrier family 12 member 4) | protein interactions | 6560 | 126 | 54 | 19454 | 5460 |
OR4N2,TOP3B,RAB6B,RAB4A,TFRC,NRN1,OR5L1,HSD17B10,KRAS,DPM2,FLOT1,PDE2A,RAB5C,LAMP2,LAMP3,RHOG,HRAS,RAB35,RAC2,GJA1,RHOH,CGAS,ARF6,CX3CL1,MARCHF4,STX6,DIRAS3,BET1,ATG16L1,CDC42,PLP2,RND2,OTULINL,ACACA,RHOU,JAGN1,RAB5A,HSPA8,SLC31A1,STX7,CHRNA7,RAB11A,RAB2A,HSD17B3,RHOB,LGALS8,LAMTOR1,ZNF655,RHOJ,LGALS3,LYPD6,MB21D2,APEX1,CLRN2 |
| 2.545e-04 | -8.28 | NT5C2 (5'-nucleotidase, cytosolic II) | protein interactions | 22978 | 109 | 48 | 19454 | 5460 |
AGR2,DRG2,COPS5,NT5C2,BTF3L4,API5,EMC4,WIF1,SURF6,CEP19,HNRNPL,COPS2,RPLP1,SIN3A,MOB3C,TUBB4B,DDX39A,GTF3C3,AHCYL1,PTGES3,COPS4,HUWE1,MOB3B,NOC4L,THRAP3,PRDM4,MAP1B,EHD4,UBE2H,DNAJB6,HERC4,PSMD14,KPNA6,DUSP3,USP5,MACROH2A1,GNPDA1,NUDT18,CMTR1,ATP5PO,SDCBP,RPA2,MAP2K1,ADNP,ATG16L1,FXR2,SQSTM1,RPA3 |
| 2.566e-04 | -8.27 | regulation of leukocyte activation | biological process | GO:0002694 | 572 | 207 | 18204 | 5365 |
IL13,CLEC7A,IL21,IFNG,CTSC,IDO1,PIK3CA,CD47,SDC4,ACTL6B,CD40LG,LEP,RNF41,TLR4,THY1,CD200,NECTIN2,PTPN11,FGL2,SRC,PRDX2,IL18,RAC2,NKAP,DROSHA,CHRNB2,EXOSC3,IL7,B2M,IL23A,SMARCB1,PRELID1,SIT1,MIR181C,HMCES,IL15,FBXO7,TICAM1,EPO,LGALS3,TNFRSF9,TNFAIP8L2,IRF1,GPNMB,PRKCQ,RPS3,SELENOK,TFRC,YES1,MIR145,KMT5B,RHBDD3,KLRC2,TESPA1,GPAM,XCL1,IL10,DUSP22,SLC39A10,VSIR,TNF,ACTB,CD2,TWSG1,CD226,DUSP10,MZB1,BATF,STAP1,PYCARD,AGER,FCGR2B,CD40,HFE,BCL6,HMGB1,CD1D,SYK,TBC1D10C,CGAS,RAG1,ARG2,IL15RA,CDKN1A,SPHK2,CCL2,TNFRSF14,IL2RA,ICOS,CTLA4,RHOH,PDCD1LG2,CYRIB,PLSCR1,CCR2,IRF4,SFTPD,CCL19,AIF1,DPP4,NLRP3,TRAF6,CD38,MIR142,CD86,CSK,SFRP1,IL6,SLC7A1,MMP14,IL12B,FGR,MIR185,SOS2,CCL5,KLHL25,SMARCE1,TNFSF8,PELI1,IL6ST,PRNP,BTN2A2,LILRB1,DHPS,FOXP3,IL12A,CD274,BCL10,LDLR,HSPD1,CD83,CCL3,PNP,MIF,SASH3,ACTL6A,JUNB,MEF2C,CD28,CD80,CBFB,BLOC1S3,RC3H2,WNT10B,CAV1,IFNB1,TYROBP,MAD2L2,LILRB4,CD81,INHA,PLPP6,CD4,IFNA2,MIR21,MIR30B,CD46,IL4,LST1,MYD88,TACR1,ZBTB16,SOCS5,IL20RB,RUNX1,SMARCD3,TNFRSF1B,TLR9,NCK1,TOX,IL2RG,SHLD1,TNFAIP3,CTNNB1,FGF10,KARS1,IL1A,DUSP3,CD209,EP300,IGF1,TNFSF18,TLR6,CCR7,STAT6,IL1B,AKT1,PPP3CA,PTPN22,BAD,PLA2G5,TIRAP,MIR125A,JAK2,IL5,CNR1,DLG1,SOD1,KLRD1,IL2,TGFBR2,EFNB1,MIR130A,NDFIP1,CCL21,XBP1,TNFSF13 |
| 2.567e-04 | -8.27 | disulfide oxidoreductase activity | molecular function | GO:0015036 | 40 | 23 | 18094 | 5411 |
ERO1A,TXNRD2,PDIA3,TXNDC12,GSTO2,DNAJC10,TMX2,TXNRD3,TXNRD1,TMX4,CCS,TXNL1,TXN,PGK1,CHCHD4,PDIA6,PDIA2,TXNDC17,SELENOT,GLRX,GLRX2,TMX3,GSTO1 |
| 2.592e-04 | -8.26 | CCL24 (C-C motif chemokine ligand 24) | protein interactions | 6369 | 9 | 8 | 19454 | 5460 |
CCL21,RIGI,CCR3,SPPL3,CXCL11,HAPSTR1,CCL5,XCL1 |
| 2.592e-04 | -8.26 | UQCC6 (ubiquinol-cytochrome c reductase complex assembly factor 6) | protein interactions | 728568 | 9 | 8 | 19454 | 5460 |
SFXN1,AIFM1,APOO,PHB2,GHITM,SLC25A51,SLC25A12,PARL |
| 2.595e-04 | -8.26 | Nongenotropic Androgen signaling | Pathway Interaction DB | ar_nongenomic_pathway | 18 | 14 | 2226 | 782 |
GNG2,HRAS,AKT1,AR,RAF1,FOS,SRC,CREB1,PIK3CA,PELP1,GNB1,PIK3R1,GNRH1,MAP2K1 |
| 2.602e-04 | -8.25 | Proteasome Degradation | WikiPathways | WP183 | 66 | 38 | 5310 | 1910 |
PSMD1,UBE2B,PSMD3,PSMA1,PSMA3,UBE2D3,PSMA5,PSMC1,PSME1,PSMB7,PSMC4,PSMB1,PSMC3,IFNG,PSMA6,PSMB3,PSMA2,H2AC4,H2AX,RPN1,H2AZ1,PSMB10,PSMB5,PSMC5,PSMD7,PSMB2,PSMD6,UCHL3,PSMD4,PSMB4,PSMB6,PSMB9,PSMD12,UBE2D1,PSMD10,UBB,PSME2,PSMA4 |
| 2.603e-04 | -8.25 | negative regulation of tumor necrosis factor production | biological process | GO:0032720 | 78 | 38 | 18204 | 5365 |
FOXP3,GPNMB,MIR132,LILRB1,IL4,TSPO,GHRL,PTPN22,MIR140,LILRB4,TRIM27,SELENOS,TLR4,NFKBIL1,MIR149,MIR98,DICER1,MIR130A,ACP5,MIR204,MIR105-1,MIR185,MIR101-1,CX3CL1,MIR708,IL10,RAD21,IGF1,VSIR,ADIPOQ,DEFB114,MIR488,CHRNA7,ARG2,MIR195,TNFAIP3,GSTP1,MIR920 |
| 2.612e-04 | -8.25 | regulation of receptor-mediated endocytosis | biological process | GO:0048259 | 118 | 53 | 18204 | 5365 |
AP2M1,B2M,VEGFA,PCSK9,APOC2,ATAD1,AP2A1,PICALM,SFRP4,PSEN1,ARF6,PICK1,CCL19,TBC1D5,CBL,MKLN1,IL4,OPHN1,MIR17,CCL21,TF,LRRTM2,H1-1,RALA,HPCA,GH1,ARF1,MIR185,CD63,PPT1,SDCBP,ADIPOQ,LRRTM1,LPAR1,FLOT1,VAC14,SNAP91,HNRNPK,DLG4,CCDC32,GREM1,MIR92B,HFE,DKK1,SGIP1,ANGPT1,APLN,MIR205,ITGAV,CLU,SYK,MTMR2,WASL |
| 2.622e-04 | -8.25 | SAE1 (SUMO1 activating enzyme subunit 1) | protein interactions | 10055 | 129 | 55 | 19454 | 5460 |
SUMO1,CFTR,EDEM3,RPA2,RPRD1B,USP39,UBE2M,SOD1,RPA3,BAP1,TRIM3,FBXW7,BCL6,MYC,DHPS,BAG3,MCM3,UBE2E3,OSGEP,NRP1,RIT1,UBE2H,UNC79,CALU,UBE2I,PPP2R5E,PSMB6,MAD2L2,USP5,RAF1,E2F4,FAF2,EZH2,FURIN,CYP1B1,PQBP1,EWSR1,ABCE1,UBE3A,PDE12,KRAS,KPNA2,UNC119B,PAX6,CTSC,RIGI,EIF3D,FKBP4,SRP14,TYMS,TRIM35,SUMO2,SUMO3,RHOH,EGLN3 |
| 2.623e-04 | -8.25 | SFT2D3 (SFT2 domain containing 3) | protein interactions | 84826 | 21 | 14 | 19454 | 5460 |
RABAC1,TMEM147,STX5,VAMP3,RPA3,RAB1B,LAMP3,YIPF5,GORASP2,LAMP2,RAB2A,GOSR2,RAB5C,RPA2 |
| 2.637e-04 | -8.24 | SHB (SH2 domain containing adaptor protein B) | protein interactions | 6461 | 76 | 36 | 19454 | 5460 |
HRAS,RAB35,GJA1,HNRNPL,RHOJ,STX6,EGLN3,LCP2,CAV1,SRC,PIK3R1,ATG9A,RAB11A,IL2RB,CUL3,EPS8,YWHAG,NTAQ1,LAMP3,AR,LAMTOR1,RHOB,EPHA2,JAK1,RAB9A,RAB5A,KRAS,KIT,SLC31A1,STX7,IL2RG,DDX39A,FGFR1,RAB4A,MET,GRAP2 |
| 2.637e-04 | -8.24 | PGM3 (phosphoglucomutase 3) | protein interactions | 5238 | 76 | 36 | 19454 | 5460 |
KRAS,TNFSF8,DCP2,DUSP26,OLA1,RPA3,GLUL,VIPR1,UAP1,RPA2,DISC1,AQP3,COMTD1,LAP3,TP53,QTRT2,GABRA1,PGM1,YES1,PRNP,APLNR,EGLN3,LMBR1L,CCNF,PHB1,SNX17,NUDT9,BLVRA,SLC2A1,SMAD4,UBE2H,FAM174A,GPR17,CUL3,GLO1,BAG3 |
| 2.651e-04 | -8.24 | DPM1 (dolichyl-phosphate mannosyltransferase subunit 1, catalytic) | protein interactions | 8813 | 158 | 65 | 19454 | 5460 |
TFCP2,SKA3,AURKAIP1,SOX2,TUBA1A,RAF1,B3GNT2,DPM2,HUWE1,ZBTB16,IGF1R,HAPSTR1,BCKDK,RB1CC1,SLC25A28,TIAM1,TUBG1,MAP3K14,DDRGK1,HDAC6,WWP2,NFKB1,ELK1,EGLN3,TMPO,PRNP,RHOH,FZR1,SPPL3,TES,PHB1,GRM2,RPA2,CFTR,CDK7,RND2,GABRA1,CDC42,BET1,TOMM22,ATG16L1,FBXW7,UFL1,EP300,RAB9A,RPA3,UBE2H,ILK,NTRK3,ATP1A1,RC3H2,FAS,CUL3,MYC,ESR2,VIRMA,FBXO22,RHOJ,PTEN,BST2,MIDEAS,CCNF,PHF12,STUB1,LMBR1L |
| 2.651e-04 | -8.24 | NPEPPS (aminopeptidase puromycin sensitive) | protein interactions | 9520 | 158 | 65 | 19454 | 5460 |
METAP2,CCNF,ESR2,FBXO22,LRRC8A,SSH3,ZNF622,LDHA,USP14,LRRC8C,LDHB,CUL3,MYC,UBE2H,OSGEP,BRCA1,CKB,HDAC5,HSPA8,SIRT7,BAP1,RPA3,LRRC8D,STAU1,EMC1,HSCB,PRCP,STXBP1,CFTR,UBA52,CNDP2,CSNK1A1,UBE2M,GRM2,ACAA2,PAK2,RPA2,RPLP2,TCEAL8,PHB1,CAV1,PTP4A3,EGLN3,HNRNPL,DDRGK1,PDIA3,PIK3R1,LRRC8B,UBFD1,AGR2,PIK3CG,PAQR9,SAR1B,DMPK,FBXO25,CSE1L,CDK20,FAF2,SOX2,TP53,RAF1,CASK,NHERF1,CHMP4C,TFCP2 |
| 2.652e-04 | -8.24 | protein folding chaperone complex | cellular component | GO:0101031 | 41 | 23 | 19108 | 5553 |
CCDC47,PPP5C,CCT2,PFDN6,PTGES3,RUVBL1,PDRG1,PFDN2,RPAP3,SDF2L1,WDR83OS,HSP90AB1,RUVBL2,HSPB8,CCT7,BAG2,BAG3,TCP1,PSMG2,CCT8,STUB1,HSPA8,CCT5 |
| 2.674e-04 | -8.23 | TSPAN2 (tetraspanin 2) | protein interactions | 10100 | 68 | 33 | 19454 | 5460 |
LMNA,TMEM31,SIGMAR1,TSPAN3,TMEM14B,ALG11,LEPROTL1,LPCAT3,TMX2,HSDL1,VSIR,FOS,TSPAN15,TMED1,BSCL2,SNX14,FAM241B,CD9,REEP6,CREB3,KDSR,SCN3B,PIK3R3,FAM241A,MGST3,CD151,ARL6IP5,ARF6,REEP4,LGALS3,VKORC1L1,RAB35,CD63 |
| 2.682e-04 | -8.22 | GOT2 (glutamic-oxaloacetic transaminase 2) | protein interactions | 2806 | 98 | 44 | 19454 | 5460 |
CCL21,SHOC2,RPA2,METTL14,UBA52,PAFAH1B1,BCL6,HDAC5,HSPA8,COX17,PEBP1,RPA3,UBE2H,PSMD14,CFL1,CTNNBIP1,MYC,FAH,TXN,PSMD4,TXNDC12,ENO1,EZH2,HADH,E2F4,MEPCE,EWSR1,PC,PREPL,BRD3,NQO1,AGR2,COPS5,PPIB,HDAC6,LYPLAL1,GAPDH,MPG,ZMYND11,CALR,GLRX,RAB11B,AIFM1,CD274 |
| 2.692e-04 | -8.22 | ELAVL2 (ELAV like RNA binding protein 2) | protein interactions | 1993 | 161 | 66 | 19454 | 5460 |
SRSF8,ZC3H11A,RPL23A,PABPC1,RBM3,NUP42,H1-6,G3BP1,CDC40,PAIP2B,APOBEC3D,H2AX,ESS2,STRBP,ILF2,LDLR,PRR3,SRSF1,KRR1,PHB1,SYNCRIP,CDC5L,DKC1,SRSF10,HNRNPL,CAND1,PAIP1,TRA2A,DDRGK1,APOBEC3F,CPEB1,MOV10,GRSF1,SNRNP70,CWF19L1,RBM22,TRA2B,UFL1,RBMS2,RALYL,ZC3H14,PABPC5,RBFOX2,H1-5,TFIP11,LARP4B,ZNF326,POLR3H,PRKRA,PHAX,GCFC2,PSPC1,IREB2,MATR3,HNRNPC,HNRNPAB,CUL3,MYC,APOBEC3B,H1-1,CDKN2AIP,CASC3,ELAVL2,ZBTB38,ELAVL4,IGF2BP1 |
| 2.707e-04 | -8.21 | primary lysosome | cellular component | GO:0005766 | 156 | 66 | 19108 | 5553 |
CCT2,SDCBP,CYB5R3,RNASET2,RETN,TRAPPC1,RAB3D,SNAP23,SURF4,RAB5C,PSMD1,TTR,CTSA,RAP1B,CCT8,ATP8A1,NCSTN,B4GALT1,HEXA,DNAJC5,CPNE1,DNAJC3,TUBB4B,STX7,TMEM30A,GLIPR1,RAB37,NPC2,DSN1,TUBB,PRDX6,SERPINA3,GDI2,HEXB,LAMTOR1,BST2,PLAC8,TOM1,FAF2,TMEM179B,GCA,CTSC,PSEN1,HEBP2,PADI2,SYNGR1,AGA,NDUFC2,CMTM6,BRI3,FABP5,LAMP2,TOLLIP,LYZ,VAMP8,PRCP,SNAP29,VAMP1,VAMP7,ACTR2,PYGB,FTL,PYCARD,CD63,GGH,STOM |
| 2.707e-04 | -8.21 | azurophil granule | cellular component | GO:0042582 | 156 | 66 | 19108 | 5553 |
CCT2,SDCBP,RNASET2,RETN,CYB5R3,TRAPPC1,RAB3D,SURF4,RAB5C,SNAP23,TTR,PSMD1,CTSA,NCSTN,B4GALT1,RAP1B,CCT8,ATP8A1,DNAJC5,CPNE1,HEXA,RAB37,NPC2,DNAJC3,TUBB4B,STX7,TMEM30A,GLIPR1,TUBB,DSN1,PRDX6,GDI2,SERPINA3,FAF2,GCA,TMEM179B,CTSC,PSEN1,LAMTOR1,BST2,HEXB,TOM1,PLAC8,AGA,NDUFC2,HEBP2,SYNGR1,PADI2,LAMP2,TOLLIP,CMTM6,BRI3,FABP5,PRCP,SNAP29,VAMP1,LYZ,VAMP8,GGH,VAMP7,ACTR2,PYGB,PYCARD,CD63,FTL,STOM |
| 2.727e-04 | -8.21 | TGFB1 (transforming growth factor beta 1) | protein interactions | 7040 | 309 | 115 | 19454 | 5460 |
FKBP1A,CTBP1,SDC2,ADSS2,RPL27A,WDR77,ITGAV,FXR2,MLH3,HSPA8,DDX5,BMPR1A,DDX39B,TMEM106B,RPS5,KLK5,CCT2,ATP1A3,FTSJ3,GGH,MCM4,HNF1B,RPL10,STAT1,TUBB,SMU1,RPS11,EIF1AX,RPN1,PDHA1,GFPT1,PPP2R1A,SOX2,EEF2,RPS4X,PSMA1,RUVBL1,PCNA,RUVBL2,SLC35G2,SLC39A7,MKLN1,FHL3,MMP9,BAG2,SLC25A5,HSPD1,CCT8,TGFB2,DDX1,HSPB1,RHOG,FEM1B,PDIA3,PIK3R1,STOML2,DIRAS3,RPS10,RPL7,SUMO2,RPL9,HECTD1,ACACA,CCL3,CFTR,CAPN1,LPXN,HSPA5,EIF5B,SMC4,FBXW7,TLR2,SQSTM1,EPHA2,ATP5F1A,TUFM,GMPS,DHPS,CDC20,TXN,EIF4H,KLK9,PSMC5,GANAB,RPS12,STUB1,RPS3,EIF4A3,FBLN5,ITGB8,PSMC3,NDUFS3,MAP2K3,EEF1A1,MTA3,LY6H,RPS13,CTNND1,NUP107,HUWE1,HNRNPK,THRAP3,TGFBR2,RPL23A,AKAP8L,BCL10,RPL24,CCL5,CDK9,FIBIN,FMOD,EEF1B2,SMAD3,TIMM8B,RPL12 |
| 2.728e-04 | -8.21 | GK (glycerol kinase) | protein interactions | 2710 | 87 | 40 | 19454 | 5460 |
RPA3,EXD2,SLC22A6,DR1,AKAP1,AOX1,MAVS,TNF,VDAC1,FBXL4,TOMM20,SLC5A6,FKBP8,AZGP1,MTCH2,MGARP,GK2,RPA2,FOXS1,SLC22A8,HBB,GHITM,AIFM1,PTPN1,CCNF,CHRM4,STUM,UBP1,RMDN3,SLCO1B3,COX20,MGST3,APLNR,MARCHF5,SLC25A46,SYP,PDCD1,RIC3,FIS1,NRP1 |
| 2.728e-04 | -8.21 | FANCC (FA complementation group C) | protein interactions | 2176 | 87 | 40 | 19454 | 5460 |
PRPF31,DNAJC5,USP14,CTNNB1,SPATS2L,HSP90AA1,COL1A2,POR,SMAD4,BRCA1,AZIN1,MAP1LC3A,FAAP100,RB1,EIF2AK2,SRC,STAT1,SPTAN1,PRDX3,CCNA2,GABARAPL2,CAPN1,CCND1,EBLN2,GSTP1,RPL18,PIK3CA,CTBP1,STMN2,CDK1,HSP90B1,IK,HSPA8,BMPR1A,GABARAP,FANCG,KRAS,MLH3,FBXW7,TGFBR2 |
| 2.734e-04 | -8.20 | MAPK14 (mitogen-activated protein kinase 14) | protein interactions | 1432 | 340 | 125 | 19454 | 5460 |
TRAPPC1,FASTKD5,FKBP8,PIWIL2,TOLLIP,MOB3B,EEF1A1,DUSP1,MAP2K3,ZNHIT1,MTCH2,TP53,CDK4,TAB2,TFCP2,NLRP1,RB1,CD4,CDK6,METAP1,SMAD3,EEF1AKMT3,MAP2K6,PLG,CSNK2A1,COPS5,SHC1,SQSTM1,RPA3,PPM1G,PML,MAPKAPK3,MEF2A,MARS1,HDAC3,NF2,GREM2,INTS6L,SPTBN1,SNRPN,DCTN4,RPA2,PTP4A2,BTG2,SLC12A2,CSNK2B,RPS20,PLCB2,CCNF,CREB1,DUSP10,JUNB,RPL22,GORASP2,AKT1,RALB,PTPN11,EPHA2,STK11,SRSF7,HSPD1,MEF2C,GADD45A,PAK6,JUN,NUP153,MAPK10,SNAPIN,EEF2,MARCKSL1,MAX,TRMT1L,DCUN1D5,NME1,NGB,SEC61G,TYMS,SH2D1A,KRT8,GYS1,DUSP6,MYEF2,ELK1,HSP90AB1,MITF,PRDX1,DYRK1B,PTPN5,CBL,BCL2L1,HSPB1,IKBKB,CDK5RAP3,TRAF6,HSPA8,EP300,DDIT3,SMARCD3,DUSP9,SNRPA,FLYWCH2,SRSF2,OXCT1,ADRB2,ELK4,CDKN1A,MAPKAPK5,CSNK1A1,ADSS2,PAK2,MAP2K1,LRRC1,MIDEAS,NFKBIA,ELK3,TCEAL1,STAT1,TAB1,PRPF31,SNRPB,MYC,HSP90AA1,SP1,HTRA2,RPS6KA4 |
| 2.738e-04 | -8.20 | Mitochondrial translation | REACTOME pathways | R-HSA-5368287 | 94 | 46 | 10285 | 3229 |
AURKAIP1,MRPS18C,GFM1,MRPL22,CHCHD1,MRPL9,MRPL16,MRPL13,MRPL57,MRPL53,MRPS18A,MRPL11,MRPL47,MRPS18B,MRPL50,MRPL33,MRPL41,MRPL20,MRPS28,MRPS23,MRPS33,MRPL23,MRPL49,MRPS26,KGD4,MRPL18,TUFM,MRPL12,MRPL17,MRPL24,MRPS21,MRPL40,MRPL52,MRPS9,MRPS17,MRPL36,MRPL34,MRPL10,MRPS7,MRPS16,MRPS11,GFM2,MRPS35,MRPS25,MRPL51,MRPS34 |
| 2.743e-04 | -8.20 | regulation of leukocyte migration | biological process | GO:0002685 | 231 | 93 | 18204 | 5365 |
TNF,XCL1,CALR,MIR24-1,IL1A,CX3CL1,CX3CR1,CCN3,DUSP1,SELENOK,MED23,CCL24,WASL,HMGB1,CXCL12,AKT1,CCR7,EMILIN1,CCR6,STAP1,GREM1,ITGA2,CREB3,ADTRP,AGER,CCL20,TNFSF18,PYCARD,CCL2,TNFRSF14,CD200R1,CXCL10,CCL28,TIRAP,CCR1,FUT9,CCL21,CHST2,CXCR3,RARRES2,CCL25,CCL19,AIF1,CCR2,DPP4,MSN,CRKL,CCL5,CXCL8,GPSM3,CD47,F7,MIR223,MMP14,MADCAM1,DEFB124,ICAM1,IL6,TNFAIP6,P2RY12,PADI2,RAC2,MIF,CCL3,MMP28,DDT,IL12A,ADORA1,CCL8,OXSR1,ST3GAL4,MPP1,VEGFC,CD200,THY1,LGALS3,IL34,VEGFA,IL23A,SWAP70,MSTN,PLCB1,PIK3R1,CD99L2,CCL1,TACR1,MYD88,CXCL13,MIR146A,CD81,CD9,PTGER4,PTN |
| 2.766e-04 | -8.19 | Signaling by FGFR | REACTOME pathways | R-HSA-190236 | 89 | 44 | 10285 | 3229 |
FGF16,FGF7,TIA1,PPP2CB,GAB1,HRAS,POLR2C,GTF2F1,POLR2I,PIK3CA,FLRT2,SHC1,FGF3,FGFBP1,FGFBP2,SPRED2,FLRT3,HNRNPA1,NCBP2,RBFOX2,RPS27A,SPRED1,PIK3R1,HNRNPF,FGF1,FGF23,FGFR1,FRS3,SRC,FGF10,FGF17,POLR2B,POLR2F,KRAS,PTPN11,POLR2G,GTF2F2,FGF22,POLR2L,POLR2D,UBA52,CBL,PPP2R1A,UBB |
| 2.767e-04 | -8.19 | TRIM11 (tripartite motif containing 11) | protein interactions | 81559 | 167 | 68 | 19454 | 5460 |
TBCE,CUL3,FBXO7,PSMD1,USP14,SLPI,S100A6,TRIM44,FAIM,CREB1,TRIM27,STAT1,TRIM29,PGPEP1,UBB,SMURF1,ACTL6A,PRKAB1,ASB8,EHD1,IPCEF1,CCL3,NUFIP2,LUC7L3,MCRIP2,TRIM10,SQSTM1,HNRNPA0,UBE2D3,HMGB1,PSMC1,SELENOO,XAF1,POGK,UBE2D1,PSMD7,DDX1,CBL,USP15,UBE2N,DUSP6,MCL1,MAGED2,PABPC1L,PCBP4,NUDT9,HP1BP3,NOP58,EIF2S1,TRIM35,DKC1,LYPLA1,CSNK1E,PROK1,KIF2A,RPN1,CHMP4C,PRKAG1,RNF126,EHD4,JAK1,CLPB,BAG2,TRIM11,NUP42,PSMD12,PAX6,RIGI |
| 2.768e-04 | -8.19 | cellular response to lipopolysaccharide | biological process | GO:0071222 | 208 | 85 | 18204 | 5365 |
IRF3,NFKBIL1,CSF2,SELENOS,TLR4,STAP1,PYCARD,PDE4B,CXCL1,MTDH,MIR140,NFKBIB,PTPN22,HMGB1,CEBPE,CD40,IL1B,LILRB1,CD274,SRC,AKT1,BCL10,PLSCR4,CX3CR1,GSTP1,IL6,PDCD4,TNFAIP3,LY96,CAMP,CD86,CXCL11,MMP9,MIR223,CXCL8,TNF,PLSCR3,CXCL9,NFKBIA,IL12B,IL10,MAP2K3,IL1A,CAPN2,PLAA,OPRK1,CXCL13,CXCL3,MIR146A,CDK4,CDC73,LITAF,PDCD1LG2,MIR21,GFI1,MIR17,MIR20A,TNFRSF1B,XBP1,TSPO,TLR9,CHMP5,IRAK4,TICAM2,TRAF6,CCR5,MYD88,MIR342,NLRP3,CD14,TLR2,CD36,IRF8,CD80,MRC1,PRKCE,NFKB1,HDAC5,LDOC1,MEF2C,CCL2,JAK2,TICAM1,CXCL10,MIR187 |
| 2.773e-04 | -8.19 | membrane lipid biosynthetic process | biological process | GO:0046467 | 143 | 62 | 18204 | 5365 |
ELOVL1,SMPD2,ST3GAL1,UGCG,PIGW,PIGA,ACER3,SPTSSA,B3GALT2,FUT9,ELOVL7,B4GALT4,HACD1,SPHK2,ELOVL6,CLN8,ST3GAL2,B3GALT4,B4GALT6,CYP4F22,B3GALNT1,PIGY,ELOVL4,ST8SIA4,TLCD3B,ST8SIA5,HACD3,PIGK,SLC30A5,B4GALT3,AGK,ST3GAL5,KDSR,SGMS2,ORMDL1,PGAP2,PGAP3,DEGS1,FA2H,PGAP4,GPAA1,OSBP,ST6GALNAC3,HACD2,CERS2,PRKD3,SGMS1,ELOVL3,PIGC,CERS6,DPM2,GAL3ST4,HACD4,ST3GAL4,ABCG2,SPTSSB,B3GALT1,CERK,FUT1,LARGE1,GAL3ST1,ORMDL3 |
| 2.777e-04 | -8.19 | TUBB3 (tubulin beta 3 class III) | protein interactions | 10381 | 431 | 154 | 19454 | 5460 |
COPS4,SIAE,RPL28,TRIM37,CDK20,PIWIL1,G3BP1,KRAS,SPTSSA,RPS24,CCT8,OSTM1,STK16,CHMP4C,AQP3,TUBB4B,EZH2,ISG15,TUBA1A,FAF2,SOX2,B3GNT2,RAF1,CCT7,RAMP3,EGLN3,TCP1,CCAR2,FBXO32,PHB1,LAPTM4A,SSR2,CDH13,HNRNPD,POU5F1,CBL,AGR2,XPO1,P2RY10,FAM174A,WWP2,COIL,FBXL4,STAU1,EEF1G,FXR2,NPTN,DNAL4,STK26,THBS3,HSPA8,BMPR1A,DDX39B,ANXA7,PPT1,ADSS2,CDKN1A,INSYN2A,ASB8,TOR1AIP2,ALKBH3,WDR77,TOMM22,APLNR,TUBB,AP2M1,SCN2B,CD79B,SP1,ICAM1,KLK5,BRCA1,FAS,SPCS3,HNRNPC,CUL3,MYC,ACO2,CAPZA1,SMN1,FBXO25,MEPCE,TF,DYNC1I1,CD80,MAP1B,NUPR1,TFCP2,MAP2K3,MGARP,DDX39A,CHRM3,TRIM6,ZBTB2,CDK9,LMAN1,VCPKMT,TES,EEF1AKMT3,HRAS,SYNCRIP,EFNA3,AIFM1,SHC1,SNRNP70,COPS5,CD81,HDAC6,LAMP3,HSPA5,GABARAP,ABCC2,METTL22,ST8SIA4,IRF7,RNF113A,MTDH,CST11,WNT7A,PML,BAP1,INPPL1,SHOC2,HAUS2,CCL18,RARS1,HEXIM1,TCP11L1,CFTR,CDC42,HCST,GABRA1,XCL1,RILPL2,VIRMA,COPE,KCTD9,PTEN,TMEM108,MSN,KLK6,TUBA1B,CHRM4,CCNF,GZMK,UBE2H,TXNIP,F9,SPOP,USP14,TAF5L,SMARCA5,RSPH1,SLC25A1 |
| 2.787e-04 | -8.19 | CCNE1 (cyclin E1) | protein interactions | 898 | 115 | 50 | 19454 | 5460 |
SMARCB1,CDK4,E2F4,TOP3B,CKS1B,DDX39A,CDKN2C,CDK5,PCNA,KLF10,TUBG1,CDKN1B,CISH,CTNNB1,GRM1,FZR1,CDK9,CDK6,RB1,MYBL2,CDK1,TRIM36,CKS2,NFYB,H1-5,CDKN1A,CDK7,FBXW7,NF2,COIL,NBN,SMARCD3,TERT,SF3B1,BRCA1,TFDP2,CCT2,SPOP,H1-1,STK11,RRN3,CUL3,MYC,CREBBP,AKT1,MCM3,AR,RHOBTB3,PSMA6,CSNK2B |
| 2.800e-04 | -8.18 | NNT (nicotinamide nucleotide transhydrogenase) | protein interactions | 23530 | 170 | 69 | 19454 | 5460 |
NDUFS8,UQCRH,SLAIN2,SLC25A12,SSBP1,COMT,PHB1,CORO1C,ATP6V1A,GATD3,THY1,POR,RHOG,TMEM70,AGR2,MRPS26,UQCR11,HSPB1,MTRF1,LAMTOR2,EMC4,NDUFV2,HNRNPA1,CTNNB1,HUWE1,EMC8,ETFA,TRIM37,FASTKD5,PDE2A,FKBP8,HSPD1,NDUFA4,HINT2,EMC2,COX8A,NDUFS3,NDUFS6,PDHA1,TP53,MRPL11,TXNRD1,FAF2,EEF2,ATP5F1B,LAMTOR3,RPGRIP1L,VIRMA,UQCRC2,CCDC90B,NRP1,MTG2,AUH,PMPCA,HMOX2,TUFM,EMC1,PDHB,STAU1,RPA3,MME,SIRT7,GFM1,RPA2,ARMCX3,CYC1,MTRES1,TIMM10,UQCRC1 |
| 2.803e-04 | -8.18 | VIM (vimentin) | protein interactions | 7431 | 723 | 245 | 19454 | 5460 |
RTCB,TRIM21,RPAP3,PSMA1,PSMA2,HNRNPF,RAB8B,RPS7,MSX2,ISG15,HGS,RHOBTB1,CCR1,SMARCB1,NRSN1,ZHX1,SUMO3,SUMO2,RPS10,PRKX,DDRGK1,XPO1,YWHAG,YWHAH,AGR2,IKBKB,MAGOH,YWHAB,HSPB1,MGMT,CBL,TIMP3,HSPA8,STAU1,FXR2,UFL1,ARMCX2,MTF1,SSBP2,PPT1,PAK2,NFKBIA,SCNM1,TRIM44,LORICRIN,MCPH1,FAM83B,TRIM29,ATP6AP2,DES,ESR2,PPP5C,LRIF1,LDHB,SFN,MYC,BAG3,PSMD1,BTF3,PSMD14,CYP3A43,ARMC7,SERPINH1,YAE1,CRMP1,TCEA2,PSME1,BHLHE40,ADRA1A,MAP1B,ABCE1,KPNA2,MEPCE,TP53,WBP11,ESS2,RPAP2,NEFL,TFCP2,NUPR1,TAB2,UBE2N,CD4,FZR1,CDC5L,SLAIN2,TMPO,MYL12A,KARS1,COPS5,BECN1,H2AC4,AGPAT1,USP15,TNFRSF14,PML,BAP1,RNF113A,RBM22,HSPA5,CAPN1,ING5,MAFG,CFTR,NEK2,PTPN22,TRIM68,RPA2,TRIM36,UBE2M,HEXIM1,GCFC2,CREB1,CCSER2,PSMC5,CEP41,ADRM1,EIF4H,KCTD9,ROCK1,SMURF1,IDE,CEP85,AKT1,PSMB2,ST13,BICD2,RC3H2,NIF3L1,UBE2H,GADD45A,AKT2,ZYX,SCYL2,TRIM37,LASP1,FLOT1,PSMD12,PNMA5,B3GNT2,RAF1,RPL29,KIAA0408,CTSA,NGB,VPS33A,EZH2,PSMB5,FOLR1,THOC2,DEFB1,KRT8,HYPK,TRIM15,SPTAN1,OCRL,INA,PPIA,PPP2R5A,PDIA3,PPM1B,RB1CC1,RASSF8,STX1A,AHSA1,WBP2,THOC3,PSMA3,NMRAL1,RABAC1,CDKN1A,PSMB7,ARCN1,ANXA7,RNF208,LGALS3,DYNLL1,TUBB,PDLIM3,IP6K1,RAB11A,CUL3,SAMHD1,YWHAZ,LMNB1,HTRA2,SP1,FAM107A,HSP90AA1,EMC2,EGFL8,NOC4L,FBXO25,TRIM62,MAP1LC3B,RAD23B,RCHY1,EFNA3,PEX5L,RPL12,SMAD3,TES,PRNP,PPP1R18,ZBTB2,CDK9,FAM118B,NFKB1,HDAC6,PSMD7,NME2,DVL2,RPA3,SQSTM1,MTDH,SYVN1,HMGB1,TTR,CERS2,FABP4,FAM161A,CCND1,METTL14,GRM2,TOX4,CDK1,WTAP,EIF4A3,CTTN,STUB1,GXYLT1,CCNF,ACAT1,SPIN3,NR1H2,TXN,NDN,VIRMA,USP14,PPP1CC,BRAP,IVNS1ABP,ARFGAP3,MAPRE1,CDC73 |
| 2.804e-04 | -8.18 | Toll_tir_struct_dom_sf | interpro domains | IPR035897 | 27 | 17 | 18521 | 5414 |
SARM1,TLR7,TLR10,TLR3,TLR4,PIK3AP1,TICAM2,TLR1,TICAM1,IL1RAP,TLR5,TLR6,TLR8,MYD88,TLR9,TLR2,TIRAP |
| 2.821e-04 | -8.17 | regulation of mRNA stability | biological process | GO:0043488 | 269 | 106 | 18204 | 5365 |
MIRLET7C,MIR130A,MIRLET7B,VIP,CNOT6,MIR497,MIR20A,MIR320A,MIR214,HNRNPA0,CIRBP,PRKCA,MIR181D,MIR206,FXR2,MIR373,MIR16-1,MIR491,ZC3H14,HNRNPC,MIR424,PABPC1,MIR200C,IGF2BP1,TENT5C,MIR708,TIRAP,MIR125A,EXOSC8,LARP4B,MIR98,MIR211,MIR23A,MIR495,YTHDF1,ELAVL4,BOLL,AKT1,DHX9,TRAF2,MIR191,MIR145,HNRNPD,TNRC6C,CNOT6L,MIR9-1,PDE12,CNOT2,ROCK2,MIR192,MIR24-1,MIR212,MIR149,MIR519D,MIR146A,METTL14,MIR96,MIR30B,MIR100,MIR193A,DCP2,MIR625,ALKBH5,SYNCRIP,MIR342,MYD88,MIR106A,YTHDF2,MIR195,MIR210,EXOSC3,IREB2,MIR137,FASTKD5,CNOT7,RC3H2,MIR181C,MIR204,MIR423,CARHSP1,MIR130B,MIR140,TENT4A,NRDE2,MIR190B,MIR26B,MIR340,CNOT8,MOV10,MIR885,MIR1-1,ROCK1,TRAF3IP2,AGO1,MIR142,MIR135B,PAIP1,MIR223,MIR34B,MIR106B,THRAP3,APEX1,TENT5D,MIR185,RNASEL,PCBP4 |
| 2.842e-04 | -8.17 | HMMR (hyaluronan mediated motility receptor) | protein interactions | 3161 | 101 | 45 | 19454 | 5460 |
RNF181,TUBB4B,VPS33A,KIF2A,TUBA1A,CSNK1E,TBK1,RAF1,BACH1,SLC39A7,CAMSAP2,CDH13,INSYN1,NDC80,HMG20A,EGLN3,NAT2,STX5,TRIM36,CSNK1A1,ABCB1,CSNK1A1L,CFTR,MORN4,H1-5,STAU1,EIF5B,EP300,HSPA8,PML,SLX1A,MAPRE1,UBE2H,BRCA1,GMNN,H2BC9,CUL3,CSK,JAK2,VIRMA,ACTB,DYNLL1,FBXO22,TRIM54,RAB28 |
| 2.842e-04 | -8.17 | ZC3H15 (zinc finger CCCH-type containing 15) | protein interactions | 55854 | 101 | 45 | 19454 | 5460 |
FAF1,RPS24,KRAS,TP53,TRAF2,ISG15,DNAJC2,SRP72,THOC2,THOC1,MRPL50,RPS16,DNAJC1,RPS10,FZR1,CEP19,CETN2,RBM42,IFI16,DDRGK1,CSNK2A1,XPO1,SNRNP70,DRG1,MED4,THOC3,SQSTM1,STAU1,UFL1,G3BP2,GINS3,MTF1,TRIM36,HEXIM1,CCNF,PSPC1,PTEN,RPS20,ESR2,CUL3,TM9SF4,MYC,UBE2H,THOC6,MAPRE1 |
| 2.855e-04 | -8.16 | MET (MET proto-oncogene, receptor tyrosine kinase) | protein interactions | 4233 | 248 | 95 | 19454 | 5460 |
SNX2,RHOH,HSP90AB1,PTK7,NRSN1,S100A8,GJA1,SH2D1A,NCR3LG1,NCK1,CBL,PIK3R1,SHC3,CTNNB1,KRAS,NDUFA4,HGS,RAF1,SNAPIN,GNB1,SLA2,GNG12,FAS,HSP90AA1,NTRK3,MYC,PIK3R3,SFN,SOCS5,RANBP10,STAP1,ITGAV,DNAJC3,TMEM106B,HADHA,TERT,VAV2,SLC25A3,SYK,HSH2D,FZR1,CAV1,ITK,HRAS,CDK6,SHC1,FGR,DPP4,CALR,SCGB1D1,CNR1,ARF4,SOCS2,PTGES3,SPSB1,IGF1R,TFRC,SPSB3,SFTPC,TP53,CDK4,SOCS3,MAP2K3,DAPK3,RHOJ,YES1,VIRMA,SRC,GAB1,STUB1,CTNNA1,CTTN,SEC61A1,PTEN,SDF2L1,TRIM23,EPHA2,STK11,CALU,PTPN11,ARL6IP6,DNAJC5,NF2,GPIHBP1,PIK3R2,HSPA5,INPPL1,RHOU,ITM2B,BANF1,SSR1,FGFR1,MET,KDELR2,NTPCR |
| 2.857e-04 | -8.16 | CPSF3 (cleavage and polyadenylation specific factor 3) | protein interactions | 51692 | 138 | 58 | 19454 | 5460 |
CCNF,CPSF1,STUB1,CSTF3,ESR2,TAX1BP1,RUNX1,CPSF2,MYC,PAPOLA,RAB11A,CDC73,FAM107A,UBE2H,RIT1,FAS,HSPA8,P4HA2,PRKCB,EP300,RPA3,SIRT7,EMC1,IRF7,HSCB,UFL1,STAU1,FBXW7,NOP53,CPSF4,ATG16L1,PAFAH1B1,CSNK1A1,RPA2,P3H1,GRM2,SSU72,CDC5L,FZR1,PPIB,YWHAG,COPS5,DDRGK1,WWP2,MED4,HSPB1,CLP1,DDX23,SNRNP70,ABCE1,BAG2,UBE2A,MDC1,DHX16,KRAS,G3BP1,CSTF2T,NUPR1 |
| 2.867e-04 | -8.16 | Nucleotide Excision Repair | REACTOME pathways | R-HSA-5696398 | 112 | 53 | 10285 | 3229 |
PIAS1,CDK7,MNAT1,EP300,POLR2B,CETN2,POLE3,INO80E,POLR2F,POLR2G,GTF2H2,POLR2D,UBA52,POLR2L,TCEA1,PARP2,UBB,COPS2,RFC2,ACTL6A,POLD4,ACTB,SUMO2,CCNH,COPS7B,POLD2,PRPF19,RPA2,RPA3,SUMO3,RFC5,UBE2I,RFC3,PCNA,RPS27A,RAD23B,GTF2H5,COPS4,RFC4,TFPT,COPS5,RUVBL1,POLE4,ERCC3,UBE2N,UBE2V2,POLR2C,LIG3,GTF2H4,POLR2I,SUMO1,INO80C,COPS7A |
| 2.868e-04 | -8.16 | GOLGA2 (golgin A2) | protein interactions | 2801 | 720 | 244 | 19454 | 5460 |
NDC80,UBXN6,RASSF8,GJA1,MYEF2,DNM2,PRPF18,SNX18,YIPF3,RAF1,LYPLA1,ITGB5,STX12,TMT1A,TRIP4,ZYX,FANCG,ENKD1,TMED7,ZBTB16,LASP1,TTC23,PRPF31,SMARCE1,PKP4,RAB11A,TMED4,ZNF250,EXOC8,SCFD1,ZMAT2,CDC7,SNRPB2,CHCHD3,LGALS3,EIF4A2,CDKN1A,LMO4,RAB6A,NDE1,ALKBH3,NDUFA5,MFAP1,TCF19,ATP5PO,TXNL1,ATP6V1G1,FTL,STX7,ZDHHC17,NSFL1C,HSCB,PID1,TLE1,FOXC2,ERCC3,FNDC11,ZNF688,SMG9,SSX2IP,EEF1AKMT3,CAV1,HTRA1,ALCAM,SELENOV,PPP1R18,COG1,MAP2K3,MLLT6,MSRB3,CTXN1,PLAAT5,CTLA4,GNG5,PQBP1,RAB1A,TSSC4,HYCC2,TRAF3IP2,NTAQ1,CIAO1,EMILIN1,BAHD1,CDC73,CCHCR1,STK24,ATOSB,UBE2I,CAB39,TMEM74,CINP,EAF2,VIRMA,CTTNBP2NL,RHOJ,MAGOHB,NDN,ABHD17A,FAM161A,ATG16L1,SAP30BP,SH3GLB2,LIMS2,GOLGA5,DCTN4,CDK1,RAB33B,SQSTM1,DVL2,RPA3,VPS28,UTP23,MBD3,PIK3R2,FBXW7,SMCP,SPATA2,GAS8,XPO1,SHC3,MAGOH,STAMBPL1,H2BC17,STX5,CEP57L1,SIN3A,RAB1B,TTC9C,CSTF2T,SPG21,MAGEB10,SUPT5H,ARL4A,HGS,CSTPP1,SMARCB1,PDHA1,RAB4A,OAS1,MYO1B,POLDIP3,CCAR1,CDCA7L,ZNF609,PSMA1,CHCHD2,SNRPB,PSMD1,THAP7,RUSC2,PSMA4,LMO2,RCL1,CRMP1,GCC1,CKB,DKK3,DLG4,SCNM1,TRIM44,ESR2,FBXO22,TRIM29,PSMD4,LMO3,TSHR,ISCU,BET1,NUP62,ZBTB42,GAMT,RAMAC,EP300,OR1M1,STK26,FAM50B,SLU7,STAU1,FXR2,SRSF2,API5,EDEM1,RBM17,USP2,CENPP,ATP6V1D,USP15,NXT2,CCDC92,CDC5L,STX6,MYL12A,RAB39B,LMAN1,LCP2,MIF,TMED9,EGR2,ZNF581,IPO8,FURIN,GRAP2,ARPC3,DISC1,NEFL,EFHC1,RBM41,TCEA2,MNAT1,RAB3B,GORASP2,H2BC9,PTPN11,FAM193B,ALKBH2,MORF4L1,SLC25A1,RAB2A,GZMK,UBE2H,STN1,EIF3G,SNTA1,MOB4,UBN1,ZBTB33,DCLRE1C,DYRK1A,TRAF1,POLR1D,CCNH,TFIP11,CLIP3,IDH2,RPA2,SPRYD4,RAB9A,RAB29,ARHGEF6,BCL6,GRPEL1,RBM22,KDM1A,HDAC3 |
| 2.869e-04 | -8.16 | B_cell_lymphoma_unspecified | COSMIC cancer mutations | B_cell_lymphoma_unspecified | 32 | 19 | 16828 | 4835 |
IDH1,KRAS,HRAS,SF3B1,SRC,CDKN2C,JAK2,IDH2,NOTCH2,CTNNB1,KIT,TP53,PTEN,CDH11,EZH2,MYD88,TPM3,CD79B,PIK3CA |
| 2.873e-04 | -8.16 | TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1) | protein interactions | 10454 | 245 | 94 | 19454 | 5460 |
MDM2,WDCP,CD274,LCMT1,TRIM45,SSX2IP,USP15,MOV10,ZMYND11,TSSC4,HAPSTR1,TAB2,PSMC3,MAMDC2,TP53,TNRC6C,SMURF1,VIRMA,F10,GANAB,TMEM74,TRIM24,PTPMT1,BICD2,UBE2H,EMILIN1,IFI35,MORF4L1,CFL1,RACGAP1,TOMM20,POLDIP2,HSPA5,BAP1,DVL2,SOD1,PML,ZMYM6,UBE2M,WTAP,WDR83,PRMT2,CDK7,OCRL,EGLN3,CNTROB,SLMAP,HSP90AB1,STK3,PPP2CB,CYB5A,RPLP1,IKBKB,CDK5RAP3,TRAF6,YWHAB,IFI16,YWHAG,XPO1,YWHAH,SPATA2,STK4,TNF,TRIM26,S100A10,BAG2,ISG15,PPP2R1A,TRAF2,MANSC1,TRIM29,RPL10,ESR2,CRYBB3,BST2,CKB,YWHAZ,PSMD14,HSP90AA1,MTG2,NXPH3,SFN,UFL1,BMPR1A,DDX39B,HSPA8,LNX2,MAPKAPK5,ALKBH3,DUSP14,ASRGL1,LAP3,FBXO42,TIRAP |
| 2.880e-04 | -8.15 | AKAP10 (A-kinase anchoring protein 10) | protein interactions | 11216 | 35 | 20 | 19454 | 5460 |
UBXN6,LAMP2,ATG16L1,MYC,RAB11A,ARFGEF1,LAMP3,DCTN4,RPA2,LAMTOR1,RAB4A,NHERF1,HAX1,RPA3,S100A6,DUSP9,EEF1AKMT3,OVGP1,RAB9A,RIGI |
| 2.895e-04 | -8.15 | ERCC2 (ERCC excision repair 2, TFIIH core complex helicase subunit) | protein interactions | 2068 | 79 | 37 | 19454 | 5460 |
MTDH,RPA3,MNAT1,KRAS,HSCB,CCNH,ISG15,MAP1LC3B,CDK7,TOP3B,TP53,GTF2H5,CDK1,RPA2,CDC7,ACAT1,GTF2F1,GTF2H2,SSR2,ELK1,MAD2L1,CETN2,ESR2,PRNP,XPO1,GTF2E1,AR,ERCC3,MYC,CIAO1,CUL3,BRD3,TOPBP1,RIT1,SKIC8,ATG3,BRCA1 |
| 2.895e-04 | -8.15 | WDR7 (WD repeat domain 7) | protein interactions | 23335 | 79 | 37 | 19454 | 5460 |
TMT1A,RAB9A,EMG1,EMC2,RAB5A,KRAS,ATP6V1G2,RAB3B,FBXW7,STX7,CMAS,ATP6V1G1,SEC22B,PPP2R1A,RPN1,USE1,RAB4A,TAF2,RAB35,CCNF,CAMLG,METAP2,VPS72,COPE,EGLN3,STX6,CHMP2A,VIRMA,MYC,OST4,LAMP2,ATG9A,RAB11A,RAB5C,ROGDI,LAMTOR1,SKIC8 |
| 2.896e-04 | -8.15 | Chronic myeloid leukemia | KEGG pathways | ko05220 | 71 | 39 | 7161 | 2463 |
BCL2L1,MDM2,PTPN11,CRKL,IKBKB,RB1,CCND1,RAF1,SHC1,NFKBIA,SMAD4,HRAS,PIK3R2,TP53,SMAD3,AKT1,PIK3R1,CDK6,TGFB2,TGFB3,KRAS,SHC3,PIK3CA,CDKN1B,SOS2,BAD,PIK3R3,CDKN1A,AKT3,NFKB1,MYC,RUNX1,STAT5A,TGFBR2,CDK4,CBL,AKT2,MAP2K1,CTBP1 |
| 2.896e-04 | -8.15 | Chronic myeloid leukemia | KEGG pathways | hsa05220 | 71 | 39 | 7161 | 2463 |
CCND1,RB1,RAF1,CRKL,PTPN11,MDM2,BCL2L1,IKBKB,SMAD4,HRAS,NFKBIA,SHC1,SMAD3,AKT1,PIK3R2,TP53,SHC3,KRAS,TGFB3,CDK6,TGFB2,PIK3R1,PIK3CA,SOS2,BAD,CDKN1B,PIK3R3,STAT5A,RUNX1,MYC,NFKB1,TGFBR2,AKT3,CDKN1A,AKT2,CTBP1,MAP2K1,CDK4,CBL |
| 2.897e-04 | -8.15 | inorganic ion homeostasis | biological process | GO:0098771 | 433 | 161 | 18204 | 5365 |
DMPK,TMEM203,SLC30A7,RGN,GRIA1,PLN,FRRS1,BOLA3,SLC12A2,NDFIP1,MT2A,CCL19,SLC25A27,FIS1,VPS54,ATP1B1,CCR2,BOLA2B,F2,ATP1A2,SLC8A1,SOD1,PICALM,TRIM24,CNR1,ATP2B4,NPPC,NHERF1,GLRX5,SLC11A2,DISC1,PML,HSP90B1,CAV2,MT1M,CCR1,PRKCB,CACNB4,BOLA1,ANKH,SRI,P2RY4,COX19,CYP4F12,ATP6V1G1,CXCL12,HFE,CCL23,TMBIM6,KCNMA1,CD40,ACO1,TMEM174,FTHL17,S100A8,PRND,SLC31A1,SLC22A17,SMDT1,DRD3,MT1E,SMAD4,STC1,CYP11B2,VAPB,IL1A,ISCU,SLC39A10,KCNJ10,CALR,BOK,CYBRD1,RHCE,SLC1A1,RHAG,VDR,ATP1A1,BAK1,HYAL2,MT3,TF,TFRC,SELENOK,CA12,CCDC47,KLHL3,MLLT6,SLC30A5,NPTN,ZNHIT1,CCL1,ATP1A3,CIB3,SV2B,FXN,STIM1,SELENON,SLC39A9,RHBG,FATE1,ATP2C1,CCDC22,PSEN1,SFRP4,MT1A,FTL,ATP6V1A,CAV1,CYP27B1,FGF23,EDNRA,MAIP1,ALPL,TMEM199,FKBP1B,B2M,TPT1,CIB2,KCTD17,CHRNA7,SLC41A1,HEXB,IREB2,CAV3,KCNJ2,P2RY1,FGFR1,EXT1,COMT,CCL3,HTR2A,CNNM4,ADORA1,TRPC1,PSEN2,MT1X,GRM1,CCL11,PRNP,CCL8,SLC25A23,TMEM165,ATF4,CYB561,FASLG,SLC1A3,CACNB2,CCL5,STOML2,ARF1,RMDN3,SLC39A13,SNX10,MYC,ATP1B3,BAX,NEO1,RHCG,SOD2,SLC39A7,FTH1 |
| 2.902e-04 | -8.14 | MTX1 (metaxin 1) | protein interactions | 4580 | 118 | 51 | 19454 | 5460 |
GHITM,SAMM50,LMNA,RPA2,CDK7,UQCRC1,HCST,MTX2,SPTBN1,TOMM22,SLC5A6,GABARAP,PHB2,SLC15A1,SQSTM1,AKAP1,GNRH1,SLC39A9,RPA3,HTRA2,DNAJC10,CISD1,TOMM40,ESR2,APLNR,ACTB,IL2RA,TMEM108,EDNRA,LMBR1L,UQCRC2,OPTN,AQP3,MAP1LC3B,KRAS,CD80,BSCL2,SFXN1,RUSF1,NDUFB5,AREL1,HNRNPD,P2RY10,SLC25A46,MICB,OPRL1,SPTAN1,ADCK1,CLN8,MAP1LC3A,AIFM1 |
| 2.902e-04 | -8.14 | VSIG8 (V-set and immunoglobulin domain containing 8) | protein interactions | 391123 | 118 | 51 | 19454 | 5460 |
CDK4,PNMA2,CAPZA2,SGIP1,FBXO3,FSTL1,THNSL1,CACUL1,SEMG2,TFG,TKTL1,IRAK4,PTDSS1,IDO1,NPSR1,SMAD9,TNFSF13,USP15,OR51E2,INA,CPLX3,VTI1B,RAB11B,USP6NL,DUSP14,KDELR2,EDF1,DRD3,SKA2,LACC1,WTAP,FOS,RAB40AL,HSPA8,TGIF2LX,FBXL4,HSPA5,FOXP2,CABCOCO1,NAA50,TESPA1,ISCA2,FAM83A,SYP,BRCA1,CSGALNACT1,RAB9B,POLR3H,TAGLN2,LYZL6,ESR2 |
| 2.903e-04 | -8.14 | TFIP11 (tuftelin interacting protein 11) | protein interactions | 24144 | 403 | 145 | 19454 | 5460 |
SPG21,SNAPIN,SOX2,SNX20,RAF1,SNRPE,SMARCB1,HDAC11,SRSF7,EFNB1,PICK1,HNRNPA2B1,FANCG,ENKD1,AP1M1,KRAS,DHX16,DDRGK1,EIF3D,UTP6,HNRNPA1,ZCCHC10,NDC80,PRPF19,MAGOH,DDX23,PPFIA3,KRT8,TSG101,TRAF3IP3,CEP57L1,DHX15,PRPF18,SNRPA1,LCA5L,CDKN1A,LMO4,NDE1,GINM1,FAM81A,MFAP1,ATP5PO,NUP50,SF3B1,FAM50B,SNRPA,LCA5,ATPAF2,CCND3,TRA2B,UFL1,SNRPB,THAP7,PRPF31,SMARCE1,HNRNPC,GPR17,PSMA4,MYC,LMO2,ARMC7,EXOC8,KIF3C,ATG3,FAS,PPP1R16A,GCC1,ZMAT2,SNRPD2,SF3B4,RSRC1,SCNM1,DES,SNRNP40,MED17,FBXO22,EXOSC8,CD2BP2,MRPL11,TP53,IMP3,TBK1,COMTD1,BHLHA9,SH3GLB1,GRAP2,DISC1,RPL23A,PQBP1,TFPT,SNRPG,PHF1,POLL,SNRNP48,TSSC4,MPG,ZMYND11,USP2,MOV10,KXD1,TRAPPC4,SSX2IP,LSM3,SNRNP70,TRIM45,CDR2L,COQ8A,CWC15,MDM2,TSPYL4,THOC1,FAM156A,PPP1R18,FAM161A,SNRPN,SAP30BP,SF3A1,LMNA,RPA2,PRPF4,ARMCX1,RPA3,BCL6,RBM22,OIP5,KDM1A,SGF29,PRKACB,VPS39,SUGP1,RRP7A,RBM7,UBE2H,CCHCR1,ELAVL2,BICD2,PSMC5,CSNK2B,GCFC2,CCNF,SRPK2,EAF2,CCDC42,THAP8,NDN |
| 2.903e-04 | -8.14 | DHX37 (DEAH-box helicase 37) | protein interactions | 57647 | 182 | 73 | 19454 | 5460 |
KRAS,H3C1,MIR155,RIGI,MIR16-2,RPL31,HAPSTR1,MIR206,RPS24,MIR17,RPS11,RAF1,MIR15A,MIR200C,AURKAIP1,FZR1,RPS10,RPS16,MIRLET7G,MIR429,ZBTB2,SURF6,DHX15,SRP14,MIR106B,MIR7-2,PRR3,MIR214,MIR25,ZCCHC9,RPS2,MIR1-1,MIR34A,IFI16,ATG9A,MIR143,DDRGK1,STAU1,MIR7-3,MIR107,MIR29A,SNAPC1,MIR10B,RPA3,MIR205,PRPF4,SIRT7,MIRLET7I,SQSTM1,RPA2,APOBEC3C,MIR21,RPLP0,MIR7-1,MIR34B,MIR1-2,RHOJ,FBXO22,MIRLET7D,VIRMA,ESR2,MAD2L2,MIR16-1,PSPC1,ZNF330,MIRLET7B,FGFBP1,ATG3,RC3H2,MIR363,RIT1,MYC,ZNF668 |
| 2.903e-04 | -8.14 | SEC13 (SEC13 homolog, nuclear pore and COPII coat complex component) | protein interactions | 6396 | 182 | 73 | 19454 | 5460 |
ESR2,RAB14,TRIM29,HAPLN2,UBE2H,RIT1,BRCA1,AR,BAG3,RAB11A,SEC13,CUL3,ZBTB5,NRBF2,STX7,B9D2,NMRAL1,BAP1,RPA3,HTR1A,FLYWCH2,SIRT7,HEXIM1,CSNK1A1,PIH1D1,RPA2,LMNA,SLC12A2,PICALM,EDEM3,ATG16L1,BET1,WDR44,MIOS,SEC23A,PSMB1,ETV6,PTPN1,MED4,AHSA1,HSPB1,XPO1,CTNNB1,PRPF19,IFI16,EMC4,SLC25A46,PPWD1,SEPHS1,SAR1B,TFG,KRAS,NUP107,DNAAF10,EWSR1,HAPSTR1,CASTOR2,FAF1,HNRNPA2B1,PSME1,CLDN12,AP1S2,SESN2,NUPR1,KLHL12,SKA3,NUP37,CSNK1E,TPD52,RAF1,CCT5,TP53,E2F4 |
| 2.903e-04 | -8.14 | PABPN1 (poly(A) binding protein nuclear 1) | protein interactions | 8106 | 182 | 73 | 19454 | 5460 |
SNRNP70,MAP4,BRD3,HNRNPD,ENY2,GAPDH,COPS5,HNRNPA1,TOP1,HNRNPL,FZR1,SPPL3,CAND1,CDK9,PHB1,SYNCRIP,EED,PDHA1,GLE1,EZH2,FURIN,ILF2,TOP3B,RAF1,NUP37,ACTN4,JUN,DUSP1,SOX2,BACH1,NUP42,KRAS,SSRP1,ABCF1,PABPC1,HNRNPA2B1,DHX9,UBE3A,ZC3H11A,EWSR1,PCNA,DNAJB4,SOS2,NRP1,OSGEP,HSP90AA1,CUL2,CUL3,HNRNPAB,MYC,SNRPB,ST13,ARHGAP21,ACTB,USP5,RPS3,STUB1,RPS9,EMC9,MET,RPLP0,ATG16L1,PABPC5,SF3A1,PAAF1,MRPL40,STAU1,UFL1,NKAPD1,ARHGEF6,SNRPA,EP300,HSPA8 |
| 2.924e-04 | -8.14 | human chr9p21.1 | chromosome location | human chr9p21.1 | 15 | 10 | 26134 | 5823 |
B4GALT1,TOPORS,ACO1,MIR873,NDUFB6,SMU1,APTX,MIR876,TMEM215,RIGI |
| 2.927e-04 | -8.14 | LIG4 (DNA ligase 4) | protein interactions | 3981 | 141 | 59 | 19454 | 5460 |
MRPS18C,RUVBL2,HNRNPA2B1,OSTM1,APTX,ZFAND2A,BTG1,KDELR1,ASPM,EEF1A1,DDX39A,NEU1,WBP1L,NPC2,MYL12A,PPIA,TOP1,CPNE1,PPP1R18,AFTPH,TRAPPC3,NHEJ1,RBM5,CRBN,GAPDH,HNRNPA1,B9D1,CLU,SMC4,FBXW7,SRSF2,XRCC5,NBN,CSNK1A1,GSTP1,IPP,ETF1,ZNF428,TPT1,LAP3,APEX1,UBE2L3,UBB,SNX3,TAGLN2,LDHA,PSMA6,ENO1,GZMK,COL1A2,CTSK,WDR20,GGH,MCM4,CIAO1,LDHB,CREBBP,CTSD,NDUFB10 |
| 2.927e-04 | -8.14 | PELO (pelota mRNA surveillance and ribosome rescue factor) | protein interactions | 53918 | 141 | 59 | 19454 | 5460 |
USP14,PSMD1,PIK3R3,CUL3,PRMT6,SLC25A1,MYC,UBE2H,ZBTB38,EIF3G,FAS,PTEN,CCNF,LMBR1L,UBA3,POLR2B,LMO4,LMO3,WDR77,PIH1D1,ZNF574,CDK1,EP300,HSPA8,EXOSC4,PRKCB,ZKSCAN1,RPL27,BAP1,HSCB,HDAC6,COPS5,XPO1,IFI16,HSPB1,HAX1,SKIC8,RPLP1,LDLR,AIFM1,HACD3,SLC25A12,CHMP2A,CDC5L,CDK9,EGLN3,FZR1,SPPL3,ANAPC13,SKA3,RPL3,POC1B,MDC1,RIGI,RUVBL1,TRIM63,CTNNBL1,G3BP1,KRAS |
| 2.934e-04 | -8.13 | MICALL1 (MICAL like 1) | protein interactions | 85377 | 90 | 41 | 19454 | 5460 |
YWHAZ,RHOB,BICD2,LAMTOR1,RHOG,H1-1,YWHAB,EPHA2,RAB11A,CUL3,DAG1,YWHAG,YWHAH,MRPL9,RHOH,RHOJ,MRPL50,KCTD3,CAV1,VIRMA,STX6,RAB35,HRAS,FAAP100,FGFR1,CAPZA2,TOP3B,EHD3,CDC42,EHD1,CD2AP,STAU1,KRAS,RAB8B,PACSIN3,STX7,RHOU,EHD4,RAB1A,RAB9A,RAB13 |
| 2.934e-04 | -8.13 | BABAM1 (BRISC and BRCA1 A complex member 1) | protein interactions | 29086 | 90 | 41 | 19454 | 5460 |
SYK,DDX39A,DNAJC25,MAP1LC3B,VPS4B,PDHA1,PRKAG1,NDUFA5,FAF1,PALM2AKAP2,EXD2,SLC25A11,PCNA,FAM168A,ATAD1,TNKS2,ARF4,MDC1,TFG,CLPX,PNOC,MOV10,AKT1,PSMA4,WWP2,CUL3,SPATA2,GMPS,PPP1CC,BRCA1,STK11,VPS4A,MRPL53,FBXO32,FAM210A,PBDC1,TRIM27,LDLR,TNKS,AASDHPPT,ESR2 |
| 2.938e-04 | -8.13 | CRY2 (cryptochrome circadian regulator 2) | protein interactions | 1408 | 188 | 75 | 19454 | 5460 |
PSMD1,RPS17,NONO,MCM4,TUFM,CCT2,ATP1A3,FBXW11,TXNIP,BRCA1,STK11,ATP1A1,HSP90AA1,RPS3,RAN,PSMC5,AP2M1,CSNK2B,PPP2R5E,EIF4A2,MATR3,PPP5C,TRAF1,RPL10,RPS14,PSMC4,CNP,DET1,CTBP1,LMNA,ZBTB42,CRY1,HSPA8,TTC1,SMC4,FBXW7,SRM,SKP1,MARS1,PSMD3,XPO1,CSNK2A1,PTGER4,RPS2,DNAJC7,KPNA1,MAP4,DICER1,PDE9A,PPP2CB,CAND1,TMPO,HSP90AB1,DHX15,CSNK1E,CCT5,EEF1A1,TRAF2,EEF2,RPN1,EZH2,FBXL3,PSMC3,CRKL,HSPD1,CCT8,HAPSTR1,RUVBL2,PICK1,BAG2,HUWE1,HNRNPK,CSE1L,DCTPP1,HNRNPDL |
| 2.952e-04 | -8.13 | UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1) | protein interactions | 56886 | 191 | 76 | 19454 | 5460 |
CTSB,ESR2,VIRMA,RAN,SEC61B,EIF2S2,BRCA1,TLR9,DNAJC10,UBE2H,CALU,NTRK3,CUL3,STAU1,EMC1,UNC45A,HSPA5,PSMC1,PML,SIRT7,TMEM106B,RPA3,DNAJC3,CD40,BAP1,AKAP1,ACP5,SF3B1,HSPA8,GRM2,HSP90B1,METTL14,PPT1,RPA2,PTP4A2,PIH1D1,UBE2M,MTF1,CFTR,GABRA1,DNAJB9,CAND1,EIF2S1,PCSK9,DCUN1D1,EGLN3,PHB1,ALYREF,GLT8D1,EFNA3,SSU72,AGR2,TNFRSF14,EDEM1,FAM20C,VPS26A,DPP4,UBXN6,PIK3R1,DNAJC30,IMMP2L,PFDN1,PSMD12,EMC2,IGF1R,RAB27A,HSPA13,NUPR1,PLD3,SELENOF,E2F4,B3GNT2,LGR4,FNTB,DNAJC25,PPP2R1A |
| 2.957e-04 | -8.13 | DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16) | protein interactions | 23341 | 227 | 88 | 19454 | 5460 |
STX5,RPLP2,SPINT2,RPL8,RPL7,DDRGK1,PDIA3,RPL6,TMEM30A,BAG2,TMT1A,SAR1B,KRAS,SOX2,DNAJC25,FAF2,MACO1,STBD1,EMC10,TAPT1,RPL18,RPN1,CA14,STIM1,SEC61B,LMBR1L,ST8SIA5,ITM2A,ESR2,VEZT,CUL3,NTRK3,FAS,CGRRF1,LMNB1,HSPA8,DNAJC3,EMC1,SEC62,OTULINL,VAPB,HSD17B11,SRPRA,PTPN1,CAMLG,DUOXA2,LMAN1,MARCHF4,TMEM199,EMC4,DNAJC7,OSBPL8,ESYT1,RPL3,EMC2,FKBP8,SRPRB,CLEC2B,LBR,RPL15,CCDC47,TFRC,SFTPC,GANAB,STUB1,CCNF,SEC63,COPE,RPL13A,RPL7A,SDF2L1,DERL1,MTDH,TEX264,RPL27,GRPEL1,HSPA5,YKT6,RPL4,TMEM106A,ST7,SEC22B,RPLP0,LEMD3,SLC12A2,USE1,HSP90B1,SSR1 |
| 2.957e-04 | -8.13 | regulation of interleukin-17 production | biological process | GO:0032660 | 48 | 26 | 18204 | 5365 |
DDIT3,TLR4,IL2,PRNP,OSM,MIR383,MIR136,CCL1,FOXP3,IL12A,MYD88,PRKCQ,IL18,MIR20A,PHB1,IL21,IL6,TUSC2,ARG2,IL23A,IFNG,IL12B,MIR181C,IL15,VSIR,JAK2 |
| 2.961e-04 | -8.12 | positive regulation of nucleobase-containing compound metabolic process | biological process | GO:0045935 | 2118 | 693 | 18204 | 5365 |
TNKS,MEAF6,RC3H2,MEPCE,IFNB1,MEF2C,MSTN,SUPT7L,PIM2,CD28,CBFB,HSP90AB1,MIR342,SMAD2,TAF2,BUD31,SLC38A3,BRCA1,ALKBH5,RBM22,IRF9,RUNX1,CD4,PSEN1,TNKS2,EGR2,ZGLP1,SNRNP70,SSBP2,HNRNPA1,DLX1,WWP2,MIR106B,CASK,MIR142,MARS1,MYC,CREB1,INPP5K,HTR2A,RPS6KA4,OSR2,MOV10,CDK1,SSBP1,APLN,MIR190B,PSRC1,TNFSF8,SMAD5,HSP90AA1,NFIL3,MED21,ACTN4,MIR708,RIT2,SMAD1,MIR200C,CCT2,IRF7,COPS5,SETD3,RNF126,PAGR1,FOSL2,SHC1,PRKCB,CTBP1,MTF1,BAZ1B,AIP,TRIM22,CIRBP,TADA3,NFE2,MIR20A,LITAF,MAFG,PICALM,CDK7,IL1A,TGFB2,RASL11A,NOTCH2,ZBTB38,TF,NCK1,IRF6,FGF10,PCNA,ABHD14B,DYRK1A,IRF2,TRIM37,NFKBIB,WASL,SOX2,CREBBP,PROX1,MTDH,ZBTB18,GREM1,CDH13,IKBKB,MYRF,TGFB1I1,EGR1,CNOT7,NR4A2,EPO,EZH1,RFXAP,UPF3B,IER2,ESR2,YTHDF2,NFYB,MIR106A,RNF187,PRKCQ,JUP,ZNHIT1,PGR,BTG2,RNF20,DCP2,MIR193A,CCNA2,SP1,PPARG,TAF7,UBP1,VPS72,MITF,ITGA6,ACSS2,SIX5,VGLL2,FGFR1,SRSF1,P2RY1,MIR340,HELT,TFPT,DNAJC2,DDIT3,TRIM27,EYA3,RFC4,USP16,CXCL10,ZNF593,MIR424,OGG1,TRA2B,FBXW11,H2AX,LDB1,ACVR1,TFDP2,BRD3,BCL7C,PLSCR1,MIRLET7C,RAF1,ARMCX3,STN1,IL10,ROCK2,YAF2,H2AZ1,DDRGK1,RBBP7,NAA15,LBH,CRLF3,RPS3,RFC5,MIR145,MSX1,ZNF770,INO80C,SSBP4,YTHDF1,HMGB1,BCL7B,MIR495,MIR23A,HRAS,ZNF304,BATF,GABPA,GTPBP1,S100A10,LYAR,ELK1,MED29,DXO,TCF21,POU5F1,FOXD3,MIR210,MYBL2,CREBL2,UBE2B,RGCC,DNM2,MIR30B,ECD,MIR519D,LDB2,RNASEL,MIR185,RNF14,UBE3A,THRAP3,ZFP64,ZNF267,RFX5,GTF2F1,ENO1,DMAP1,MIR885,PRL,JUNB,OTX2,HAS3,JUN,RXRG,PPARA,PELI1,CXXC1,MTA3,NEUROD2,ZNF263,STAT1,PKIB,CAND1,LRP6,MED31,MORF4L1,LMO2,JAK2,SMCHD1,KPNA6,DVL2,GSK3A,MLLT11,MIR206,RIOK2,CREBZF,TNFSF13,AATF,LMO4,MIR497,RRN3,TRIM24,UBE2N,CDK12,SS18,PSMC3,WDR77,NAA16,KARS1,EP300,SNX5,RFC3,CTNNB1,BACH1,HYAL2,SHLD1,UBE2V1,UBE2V2,CDC7,SMAD4,INO80E,PRMT5,MIR181C,BMPR1A,MECP2,SMARCB1,SMAD9,NFE2L2,SOX3,EXOSC3,BMPR2,TFE3,IRF1,PQBP1,UTP15,AFAP1L2,MIR625,MIR100,RFXANK,ACTR2,METTL14,NBN,IFI16,ZNF319,LMO3,CCT5,IFNG,MED17,MIR34B,MIR135B,STK16,MEF2A,ZNF609,SMARCA5,PTGES3,ATF4,TRIM21,HNRNPK,SQSTM1,POLR2G,ZNF175,PML,FAM168A,IRF2BPL,TFCP2,BMPR1B,HCLS1,FOS,PABPC1,SUPT3H,HLF,TERT,MIR491,NFKB1,TRAF6,FXR2,NDP,MIR181D,CD38,NEK2,RNF40,PLAGL1,SMAD3,CRTC2,MIR24-1,CSRNP1,PCBD1,TRIM62,TFRC,TAF9,WNT2,HNRNPD,KMT5B,MED30,KLF10,ATF3,NKX3-1,PKNOX1,MAVS,ZBTB17,KANSL3,GPBP1L1,RUVBL2,ING2,TADA1,MYD88,TAF5L,ILF2,IL4,MDC1,HSPA5,NKRF,CD81,DGCR8,MIR146A,MIR149,MOSPD1,TLR3,PELP1,RORB,CDC42,AGO1,NUPR1,SFRP1,IGF1R,RTRAF,BCL10,LILRB1,YWHAH,HNF1B,SETD7,KLF12,GTF2F2,RFX4,MAP3K12,BARX2,HEY2,IRF3,CDC5L,PRPF19,KDM1A,NR1I2,EDF1,IL5,RGMB,BUD23,ZBED1,TLR7,NUCKS1,ANKRD49,STPG4,IRF8,PRMT2,MAP2K1,HDAC5,SOX9,STAT2,HOXC4,SUB1,RBM23,CNOT6,SF3B5,TOPORS,MAP2K3,MIR192,PARM1,SCAND1,MIR9-1,TRIM8,RPRD1B,RERE,DHX9,SPP1,HOXB1,MSL2,RFC2,MBD3,HAND2,PRDM4,ZNF345,ADRB2,HCFC2,STAT6,RNF8,TRIM44,TRIM15,HMCES,LUM,ZNF668,PRIM2,LHX2,GTF2I,HEXB,FAF1,MIR195,FOXJ3,RHOG,TRA2A,TRIM52,CDKN1B,EPCAM,MIR212,RBM3,TP53,ACTL6B,NCBP2,NEK7,MIR1-1,SOST,HSPA8,CSRNP3,RAP2C,CNOT8,MIR26B,ZNF574,TRIP4,ZNF473,MGMT,ARF4,JADE1,TLR4,ZBED3,KLF4,PAX9,NDN,CDK9,TMSB4X,CDKN1A,SUPT5H,NFYA,MED4,TNFAIP1,RB1,CITED1,ILK,TAFAZZIN,NLRP3,CEBPG,ZBED4,MIR214,NEUROG2,IRF4,FOXC2,CX3CL1,RBPJ,SF3B1,ACTB,HMGA1,TNF,PDE12,RUVBL1,ING1,PHB1,MIR191,PLAC8,FGF7,TOP2B,CCT8,GTF2A2,MED11,MIR98,HINFP,MIR423,MIR204,WNT10B,SSBP3,MAD2L2,SMYD3,RIGI,PAX6,MED27,TP53INP2,GTF2A1,UCN,GABPB1,BABAM1,CD80,ZBTB16,ZNF24,SMARCD3,TNFRSF1B,TLR9,PLCB1,HDAC3,MLLT6,CDC73,ZNF507,MEF2B,MIR96,PPP1R10,ELF1,MIR223,ZNF513,CD86,SOX21,BAX,TP53INP1,ID4,IL6,EFCAB7,CD274,FOXP3,ACTL6A,PPP1R12A,SMARCE1,SLX1A,MIR130B,HAX1,E2F4,SF3B4,FGF1,MIR125A,NR1H2,E4F1,TAF11,RGMA,ATF1,CDK5RAP3,PID1,XBP1,MET,MIR320A,HNRNPAB,AR,MIRLET7B,IL2,MIR130A,CYTL1,GRSF1,SIRT7,DKC1,HMX2,NFKBIA,IGF1,CNOT2,ENY2,NEUROD6,TEF,CREB3L4,MT3,TOX,RBBP4,MAX,VDR,DYRK1B,AKT1,TGFB3,IL1B,CEBPE,PPP3CA,WNT7A,CCT7,MIR211,SERTAD2,FUBP3,EXOSC8,FGF23,BCL9,MIR137,CCAR1,IL23A,MTA2,VEGFA,SLC38A2,OSM,PIK3R1,NR2E1,PIK3R2,SETD4,KLF1,TRUB1,CAMK1,ELK4,DEK,SOX14,TCP1,FZD4,NIBAN2,APEX1,IL17F,TAF10,ETV6,ROCK1,SUPT4H1,ELK3,WRAP53,IL18,HNRNPA2B1,TFEB,MIR140,POU1F1,NUP62,ARL2BP,MAPKAPK5,WBP2,CHCHD2,PSMC5,SERTAD3,PIH1D1,MIR16-1,MIR373,TLR2,ZNF287,CYP1B1,MRPL12,XRCC5,TBK1,STAT5A,PIAS1,RNF10,AKAP8L,TCEA1,NIF3L1,SERTAD1,MED23,CNOT6L,BIRC2,YES1,UBE2L3,TNRC6C,TRMT112,TRIM32,MED9,MED10,CD40,PITHD1,NR1I3,CREB3,MED22,TRIM5,NME2,PRDX6,FOXA3,SGF29,TESC,NOG,PRR5L,EAF2 |
| 2.965e-04 | -8.12 | negative regulation of protein localization | biological process | GO:1903828 | 217 | 88 | 18204 | 5365 |
GHRL,SNX12,LMAN1,PID1,NDFIP1,CTNNA1,ARF6,TMEM59,PICALM,UFM1,BCL2L1,TRIM29,OS9,MACROH2A1,CDK9,CHGA,UBXN2B,SUMO1,ABHD17A,PPP3CA,UBE2G2,DPH3,NSFL1C,CDK5,IL1B,AKT1,DERL2,SNX33,LZTFL1,DRD3,ADTRP,PKIA,ENY2,ADIPOQ,UCP2,SVIP,NDUFAF2,ROCK2,TAX1BP3,CHP1,TXN,CCN3,JAGN1,ERLEC1,OTUD7B,INPP5E,GNAZ,PKIG,YWHAZ,SUFU,NGDN,SNX3,MIR148A,PPP2R5A,SYT4,MIR146A,HADH,LILRB4,SIN3A,CD36,FKBP1B,AP2M1,LYPLA1,CAV3,TP53INP2,KCNJ11,ANGPT1,INPP5K,IL12A,BTF3,PTPN11,CD200,GDI2,OPRM1,TMBIM1,GPM6B,KCNB1,ACVR1C,RAB23,IL12B,WWP2,UBAC2,NEO1,SFRP1,CSK,RSAD2,ERP29,GNAO1 |
| 2.971e-04 | -8.12 | KPNA2 (karyopherin subunit alpha 2) | protein interactions | 3838 | 495 | 174 | 19454 | 5460 |
PCNA,LAMB2,G3BP1,COPS4,RAD21,MCM6,PNMA5,JUN,NUP153,ACTN4,CHMP4C,EZH2,SART3,PHB1,KRT8,POLR3F,NOP58,SRSF10,INO80E,PRPF19,BCL7C,CDK5RAP3,DDX23,CDKN1B,PRKD3,NUP50,PMAIP1,SKP1,COIL,VAPB,RAN,POLR2F,RBBP4,CUL3,MCM4,SAMHD1,SMARCE1,JPT1,PRPF31,BRCA1,LMNB1,RHOB,FAS,MAGEH1,HAPSTR1,CTNNBL1,HUWE1,MSH6,ING1,CTDSPL2,LDLR,ZBTB2,NCBP2,CDK9,NFKB1,RPA3,PPM1G,SQSTM1,SMC4,NUCKS1,NF2,IRF7,MBD3,FTH1,LMNA,DCTN4,CCNF,STUB1,GSK3A,GANAB,VIRMA,PPP1CC,USP14,KPNA6,AR,TDP1,STK24,TXNIP,ANKIB1,BCL7B,SREK1IP1,RUVBL2,EWSR1,RUVBL1,KRAS,ARL4A,ISG15,TAF10,MTA2,SMARCB1,SUMO2,LYAR,HSP90AB1,HMG20A,WWP2,MDFI,IFI16,DDRGK1,XPO1,IKBKB,POU5F1,SMARCD3,EP300,DDIT3,HSPA8,SF3B1,ARHGEF39,STAU1,PHB2,UFL1,TANK,NUP62,GTF2IRD1,CSNK1A1,CMTR1,NFKBIB,LMBR1L,GTF2F1,PRMT5,MATR3,STAT1,CBX5,HNRNPC,CREBBP,MYC,FBXW11,POLR1B,COP1,MAP1B,SOS2,CSE1L,KPNA2,NEDD8,MEPCE,TP53,UBL4A,ACTR1A,ACOT13,NFE2L2,NUPR1,SPRY1,CD274,ITK,CAND1,CDC5L,RAB39B,MBD5,PPM1D,COPS5,SNRNP70,USP15,KPNA1,IRF3,BAP1,RNF113A,CFTR,CDC42,POLR1D,RPA2,RAG1,HECTD1,HEXIM1,UBE2M,ZNF330,ZBTB33,PHAX,TRIM54,TRAF1,NOPCHAP1,MORF4L1,RGL2,RC3H2,UBE2H,SERTAD3 |
| 2.972e-04 | -8.12 | TRIM2 (tripartite motif containing 2) | protein interactions | 23321 | 50 | 26 | 19454 | 5460 |
ATP6V1G1,MNAT1,CDK20,UBE2D3,UBE2K,TRIM3,LCA5,PDHA1,UBE2F,UBE2W,TP53,CSNK1E,VIRMA,CIB3,PRNP,MATR3,UBE2N,TNIK,UBE2H,HSP90AA1,UBE2E3,UBE2D1,UBE2E2,CUL3,TRIM8,TNFAIP3 |
| 2.972e-04 | -8.12 | PI4KB (phosphatidylinositol 4-kinase beta) | protein interactions | 5298 | 50 | 26 | 19454 | 5460 |
RAB14,EGLN3,STX6,APEX1,RAB11B,ARF1,S100A6,RDM1,LAMTOR1,STK24,DNAJC10,YWHAZ,YWHAB,MYC,RAB11A,SFN,XPO1,YWHAG,YWHAH,ARL5B,FBXW7,TCOF1,RAB9A,RAB5A,PTAR1,CDK7 |
| 2.973e-04 | -8.12 | RTRAF (RNA transcription, translation and transport factor) | protein interactions | 51637 | 197 | 78 | 19454 | 5460 |
CUL3,CUL2,MYC,RACGAP1,BAG3,AR,RIOK2,BTF3,RC3H2,CCDC22,SPOP,UBE2H,PAFAH1B3,CMTR1,CCNF,PSPC1,RTRAF,MATR3,RPL10,ESR2,DYRK1A,CFTR,GRM2,PICALM,METTL14,PPT1,EIF2B3,RPA2,LMNA,PIH1D1,EIF4B,RPL26L1,HEXIM1,NUFIP2,RPA3,SOD1,BAP1,RFC4,EP300,DDX5,LSM12,FBXW7,PAFAH1B2,UFL1,FXR2,G3BP2,WWP2,ACTR3B,DDRGK1,COPS5,HNRNPA1,USP15,DDX1,RCHY1,PHB1,SYNCRIP,THOC1,EIF2B2,CAND1,RPS16,DCUN1D1,FAM98A,TMPO,YTHDF2,RAF1,CHMP4C,PSORS1C2,DISC1,ILF2,ABCF1,RTCB,DHX9,ABCE1,TOLLIP,HUWE1,G3BP1,RFC2,MEPCE |
| 2.974e-04 | -8.12 | INPP5K (inositol polyphosphate-5-phosphatase K) | protein interactions | 51763 | 63 | 31 | 19454 | 5460 |
FBXO7,NTAQ1,FATE1,HMOX2,MTG2,MOV10,FAM20C,UBE2H,HSPB1,TNKS,EGLN3,UBB,RPL10,ASPM,FBXL19,CDKN1A,TANK,AAMP,ANXA7,MAD2L1BP,GPHA2,CPTP,HSPD1,ATP5PF,SFT2D2,PFDN1,ABHD10,SMN1,MDC1,TTR,HSCB |
| 2.974e-04 | -8.12 | CPNE1 (copine 1) | protein interactions | 8904 | 63 | 31 | 19454 | 5460 |
CDC42,TIMM13,NEK7,CFTR,GABARAPL2,SPTBN1,RAF1,UBE2M,WTAP,RPA2,MAP2K1,GDI2,HSPA8,RPA3,PYGB,COPS5,HDAC6,ST13,BAG3,EMC4,CUL3,KLK5,UBE2H,CCDC22,PPP5C,APEX1,STK3,BUB3,CPNE1,ACTB,TENT5C |
| 2.974e-04 | -8.12 | DSTYK (dual serine/threonine and tyrosine protein kinase) | protein interactions | 25778 | 63 | 31 | 19454 | 5460 |
TCEA1,LSM12,CXCR4,TACR3,HSPE1,GRPR,UBE2K,SLC31A1,NPTN,HCST,PSMB3,IL1R2,ATP5PB,CTDSP1,TUBB4B,RPS9,PSMB1,ARHGAP25,CD79B,VIRMA,MAD2L1,RAB14,LAMP3,MTPN,RAB5C,GPR17,DDT,CDH13,CD226,NCR3LG1,SPCS3 |
| 2.980e-04 | -8.12 | SNX1 (sorting nexin 1) | protein interactions | 6642 | 200 | 79 | 19454 | 5460 |
ENO1,CTTN,GNAO1,SYNGR1,ZBTB18,TAX1BP1,SNX3,STAT1,MAT2B,HNRNPC,RAB11A,CABCOCO1,UFD1,SDF2L1,MECP2,SYP,LAMTOR1,FAS,SNX5,DNAJB6,REEP6,KLHL1,RPA3,UGDH,EP300,RAB5A,RAB9A,SLC35F2,RTN4,HSPA8,RABAC1,GTF2I,FXR2,STX7,AGTRAP,ATP6V1C1,FUNDC1,PPP1CB,FGFR1,LSM2,SDCBP,RPA2,LEPR,EIF4B,TMOD1,HCLS1,PSMB1,DLGAP4,DERL2,SNX1,SNX2,KCTD10,ARF6,FHIP1B,WIF1,LRRC61,VPS26A,LAMP2,ATG9A,MOV10,TBC1D5,LAMP3,ATG7,PPP3CA,MED4,TMEM87A,BAG2,IGF1R,VPS26B,RUVBL2,ACVR1B,RIGI,FAM200A,ZNF397,RAB4A,GPX7,SDR16C5,HGS,SH3GLB1 |
| 2.982e-04 | -8.12 | TAS2R41 (taste 2 receptor member 41) | protein interactions | 259287 | 19 | 13 | 19454 | 5460 |
CHRAC1,SERPINB1,GAMT,MECR,LASP1,ATP5F1B,YKT6,DESI1,SNX3,SEPHS1,CBFB,EFHD2,THUMPD1 |
| 2.983e-04 | -8.12 | COP1 (COP1 E3 ubiquitin ligase) | protein interactions | 64326 | 322 | 119 | 19454 | 5460 |
GLRX,CCT7,COPS7B,NOB1,TCP1,S100A8,COPS2,RPL9,PCDH9,PHB1,CDKN1B,DCAF11,RB1CC1,YWHAB,RPL23,FOSL2,UBE2D1,PDIA3,UBE2E2,NDC80,RPS4X,COPS4,SRSF7,PDIA6,HSPD1,ARGLU1,ATF3,CCT8,RPS11,RPL18,TUBB4B,CRTC2,JUN,SOX2,RPS7,ZNF397,ZNF263,PRDX2,DYNLL1,TUBB,RPL35,TAX1BP1,RPS9,REG1A,NFKBIA,COP1,PFDN6,TRIB1,RBBP8,CCT2,S100PBP,YWHAZ,RFC5,BTF3,PCCB,COPS7A,CUL2,PYCR1,SFN,CUL3,PYGB,SKP1,UBE2D3,IL1A,NFIL3,HSPA8,TXNL1,FOS,RPS28,AGGF1,ATP5PO,DET1,RPL27A,MDM2,CHGA,CAND1,CDK6,WDCP,PTPN1,RCHY1,LANCL2,COPS5,GAPDH,LRRC40,RPL17,FN3KRP,KPNA2,RPL3,NOSIP,ZNF451,MLLT11,MSRB3,SIX5,TBK1,SNAP29,CCT5,TP53,JUNB,TXN,TXNDC12,MACROH2A1,RPS3,UQCRC2,SPOP,TRAF3IP2,ATP5F1A,TUFM,MLF1,PTPN11,RPL7A,PIAS1,SMC4,KIN,PML,ACACA,METTL14,RPS14,PCK2,BRINP1 |
| 2.988e-04 | -8.12 | PBXIP1 (PBX homeobox interacting protein 1) | protein interactions | 57326 | 206 | 81 | 19454 | 5460 |
VTI1B,DNAJB9,DNAJC1,LCA5L,DPPA2,MDM2,SLC25A17,CD1A,UQCRH,STX6,SELENON,FIBIN,CCDC127,CAMLG,DIPK2A,HSD17B11,MUL1,SLC25A28,ZDHHC15,CDKN1B,TSNAX,MDFI,CMSS1,CFC1,FAM20B,EDEM2,RIGI,SACM1L,STX8,TMT1A,LPAR2,BCAP29,STIM1,CDK8,RPN1,DISC1,CAPN2,TAPT1,NCR3,COMTD1,TBK1,PI15,B3GNT2,MACO1,CHRM3,GABARAPL1,DNAJC25,CLEC2B,CBLN4,DIPK1A,ESR2,RMDN3,CTU1,SGTA,SEC61B,SDF2L1,FAS,PPTC7,TMEM38B,MORF4L1,CCDC85B,GGH,HSCB,GPIHBP1,CLEC12B,TACR3,CYB5D2,NBN,CST11,DERL1,SSR1,GHITM,PIGW,BRINP1,TANK,FUT8,OTULINL,TMEM106A,SEC62,EDEM3,ST7 |
| 2.989e-04 | -8.12 | GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase) | protein interactions | 2618 | 209 | 82 | 19454 | 5460 |
CD274,AIFM1,SWAP70,PHB1,RB1,ARF6,TCP1,EGLN3,PPIA,G6PD,IFI16,HNRNPA1,HDAC6,AGR2,RPL24,TRAF6,DNAJC7,HSPD1,RAB1A,FAF1,ZYX,HNRNPA2B1,ZC3H7A,UBE3A,KRAS,KPNA2,PSMD12,SAR1B,SEPHS1,HNRNPDL,TXNRD1,SUPT5H,TP53,EEF1A1,EEF2,PLS3,CHMP4C,NUPR1,INPP5K,CTTN,DLST,MSN,EIF4H,AKR1C2,TXN,NDN,KCTD9,PPAT,VIRMA,MYC,CARS1,PSMA4,CUL3,SAMHD1,ATG3,BRCA1,SERPINH1,UBE2H,RIT1,BAP1,RPA3,SIRT7,HSPA8,ARFIP1,SQSTM1,DERL1,RTN4,EP300,RNF113A,UFL1,FBXW7,STAU1,EIF4E,UGP2,CDC42,PPP1CB,RPA2,ADSS2,LMNA,UBE2M,STAT6,PIH1D1 |
| 2.990e-04 | -8.12 | SSH1 (slingshot protein phosphatase 1) | protein interactions | 54434 | 71 | 34 | 19454 | 5460 |
NDUFA4,IGF1R,RBCK1,SSRP1,RAF1,TOP3B,ACTN4,EZH2,OXSR1,RAD23B,CDIPT,ACTA2,EFHD2,NECTIN2,CORO1C,DSTN,TMOD3,ACTB,UMPS,TECR,VIRMA,AKT1,PSMB2,CFL1,YWHAG,CFL2,YWHAH,ATF1,YWHAZ,FBXW11,PPTC7,HAX1,YWHAB,TMOD2 |
| 2.990e-04 | -8.12 | NLRX1 (NLR family member X1) | protein interactions | 79671 | 71 | 34 | 19454 | 5460 |
IL1R2,TOP3B,COMTD1,LPAR6,HCST,MGARP,PRDX3,RPA2,CCR1,FAF1,OSTM1,MAVS,HSPA8,HSCB,TNFSF8,RIGI,FASTKD5,CUL3,CREB3,MYC,TUFM,P2RY10,TRAF6,BECN1,IKBKB,HERC4,UPK1A,CDIPT,CD79B,IL2RA,SARM1,BRINP2,GNAI2,ESR2 |
| 2.990e-04 | -8.12 | SLC26A6 (solute carrier family 26 member 6) | protein interactions | 65010 | 71 | 34 | 19454 | 5460 |
LAMP3,CD81,TSPAN10,SLC25A46,AQP2,PDCD1,RHOB,RHOG,LDLR,RAN,HRAS,RAB35,PLP1,SLC25A17,LGALS3,RHOH,RHOJ,ARF6,HACD2,FAF2,CDC42,BET1,TP53,VAC14,LMBRD2,ERG28,SCPEP1,LPCAT3,PXMP2,SLC6A8,SLC15A1,TF,TNFSF8,KRAS |
| 2.994e-04 | -8.11 | UBA6 (ubiquitin like modifier activating enzyme 6) | protein interactions | 55236 | 144 | 60 | 19454 | 5460 |
RIGI,AHCYL1,SAR1B,CAPZA1,XPNPEP1,PSMA1,KRAS,VPS26B,PPP1R12A,RAD23B,CCR1,PGGT1B,PDHA1,CAPZA2,GTF2E2,HEXA,TP53,NAA15,CETN2,MBD5,HNRNPL,ARHGAP25,UBE2G2,SMAD9,UBE2D1,SMAD4,ATG7,PLEKHO1,WWP2,PYGB,ATP6V1G2,STAU1,UBE2D3,UCHL3,NUBP2,HELLS,RPA3,PIH1D1,OXSR1,CZIB,RPA2,SNRNP27,EHD1,MYLIP,JUNB,UBE2L3,PSMB6,FBXO22,TSN,AIPL1,RPS20,GNPDA1,UBE2S,EIF4A3,DLST,CCNF,EXOC8,H2AZ2,FYTTD1,LMO2 |
| 2.994e-04 | -8.11 | PPIF (peptidylprolyl isomerase F) | protein interactions | 10105 | 144 | 60 | 19454 | 5460 |
GFM2,PDHA1,METTL15,E2F4,MRPL11,IMMP2L,MEPCE,FASTKD5,VDAC1,ETFA,HSPE1,SRPRB,S100A10,KRAS,YIF1A,COX8A,HINT2,ZC3H11A,SYPL1,HSPD1,MRPS26,TMEM70,CHCHD1,RHOG,GRSF1,MTRF1,CIDEB,RMND1,PPIA,COX4I1,SSBP1,AIFM1,HRAS,FKBP1A,MTRES1,AGTRAP,BCL6,CRYZ,STX7,RER1,GPX4,GFM1,HSPA8,EXD2,SOD1,SYP,TUFM,PMPCA,PTPN11,GSTK1,MTG2,NDUFAF2,SUGP1,AUH,ESR2,PARL,SLC25A4,CCDC90B,TACO1,MRPL53 |
| 2.999e-04 | -8.11 | ALDOC (aldolase, fructose-bisphosphate C) | protein interactions | 230 | 104 | 46 | 19454 | 5460 |
HEXIM1,SHOC2,STXBP1,CFTR,NSFL1C,CRYZ,PEBP1,BAP1,PGK1,GPX4,GLOD4,CKB,ACO2,LDHB,BAG3,LDHA,TAGLN2,UMPS,TENT5C,VIRMA,CCNF,SOD2,MAP2K3,ACTN4,ETFA,GNL1,OLA1,FKBP2,SAR1B,IMPA2,MAP1B,FAF1,EWSR1,HSD17B10,SMAD4,AGR2,MOV10,ISYNA1,PGAM1,COPS5,PPIB,GLO1,LMAN1,FABP5,PREP,FAHD1 |
| 2.999e-04 | -8.11 | ARHGAP18 (Rho GTPase activating protein 18) | protein interactions | 93663 | 104 | 46 | 19454 | 5460 |
AP2M1,SMAP2,WDR6,DOK4,ZBTB2,JAK2,MED17,CHMP5,AFTPH,IQSEC1,EDC3,CSNK2A1,RAB11A,SEC13,MPHOSPH6,DNAJB6,SERPINB1,AGR2,LSM6,PSMD14,RHOB,PNRC1,SMAD4,ANKRD49,MEA1,BAG2,ANAPC16,HSPA8,LSM14A,SCYL2,AP1M1,LSM4,FGD2,KDM4B,DCP2,SYNRG,CD2AP,MND1,AP2S1,ENPP4,LSM2,STOM,PICALM,PALS2,TFRC,AP1AR |
| 2.999e-04 | -8.11 | POLG (DNA polymerase gamma, catalytic subunit) | protein interactions | 5428 | 104 | 46 | 19454 | 5460 |
ACAA2,MTRES1,AMACR,EXD2,GFM1,TOMM20,MTG2,AUH,PMPCA,TUFM,TACO1,CCDC90B,APEX1,TOP3B,MRPL11,NDUFS6,PDHA1,GFM2,HSPD1,SLC25A10,HINT2,MRPS18B,BAG2,COX8A,USP30,MRPS17,FASTKD5,IMMP2L,MTRF1,MARCHF5,PFDN5,P2RY10,CBR4,RHOG,TMEM70,MRPS26,SSBP1,SDHB,COX4I1,MGME1,COX7A1,YBEY,GATD3,FAHD1,HNRNPL,MALSU1 |
| 2.999e-04 | -8.11 | DIAPH3 (diaphanous related formin 3) | protein interactions | 81624 | 104 | 46 | 19454 | 5460 |
SIX5,GTPBP1,CAPN2,COMTD1,TMEM126A,MAP1LC3B,TOLLIP,TRIM37,KRAS,IMMP2L,HS2ST1,VTA1,RHOG,SMAD9,NDC80,HDAC6,XPO1,CAV1,STX6,EGLN3,HRAS,RAB35,KRT8,RAC2,PGRMC1,ATG16L1,CDC42,STAU1,KDM1A,RPA3,RAB5A,SQSTM1,RHOB,LAMTOR1,MAPRE1,NCKIPSD,CCNB1,RAB11A,RHOJ,ACTB,VIRMA,ENO1,SCN2B,ANAPC2,PHF21A,RMDN3 |
| 3.013e-04 | -8.11 | regulation of interleukin-2 production | biological process | GO:0032663 | 63 | 32 | 18204 | 5365 |
SASH3,CD83,IL20RB,RUNX1,PNP,TRAF6,FOXP3,PRKCQ,HOMER3,IL1B,PRNP,IRF4,CCR2,SFTPD,PDE4B,CD4,LILRB4,TRIM27,SPTBN1,STOML2,IL17F,IL1A,MIR181C,XCL1,TNFAIP3,TRAF2,CLEC7A,CD28,CD80,CD86,CD34,RPS3 |
| 3.016e-04 | -8.11 | NUP155 (nucleoporin 155) | protein interactions | 9631 | 457 | 162 | 19454 | 5460 |
ADRB2,RER1,STAU1,UFL1,NUP50,RAB5A,AKAP1,DUSP9,LCA5,PIH1D1,VAPB,TMEM115,SEC62,RND2,OTULINL,TOR1AIP2,PGRMC1,BET1,NUP62,ATP6AP2,MB21D2,RPS9,SEC61B,GPR89A,FAM83B,RMDN3,SLC30A7,RAN,LMBR1L,VMP1,RIT1,SCFD1,NTRK3,BRCA1,LMNB1,RHOB,MCM3,SLC30A5,OTUD7B,CUL3,VEZT,MYC,PNOC,RPS4X,NUP42,G3BP1,KRAS,TMT1A,RINT1,TMEM87A,SCYL2,MOB3C,PTRH2,CHMP4C,GLE1,STIM1,NUP153,FAF2,DNAJC25,RANBP1,CSNK1E,MACO1,STBD1,COX14,NUP35,TMEM97,RHOH,STX5,GJA1,FBXO32,PHB1,C2CD2L,REG1B,RHOG,CDK5RAP3,DDRGK1,XPO1,WWP2,TMEM209,BRIX1,TOMM20,YKT6,DERL1,MAVS,RAB9A,RTN4,SQSTM1,SYVN1,SIRT7,TEX264,RPA3,LEMD3,FGFR1,SSR1,USE1,GOLGA5,RPA2,LMNA,ST7,CDC42,SEC22B,RABL3,DYRK1A,VIRMA,RPGRIP1L,UBE2I,CTNNA1,STUB1,CDIPT,CCNF,MAPRE1,UBE2H,SNX5,GORASP2,CEP85,RPL7A,FKBP8,STX11,KPNA2,NUP107,NEDD8,IGF1R,YIF1A,RAB27A,BHLHE40,SLC25A11,NSDHL,SLC25A10,FAM169A,NUPR1,SURF4,UBIAD1,MAP1LC3B,LBR,TP53,CCDC47,SURF6,CDC5L,STX6,TMPO,CDK9,LMAN1,FZR1,COG1,DNAJC1,RAC2,HSD17B11,CAMLG,EHBP1,ARL10,SRPRA,PTPN1,STT3A,STYK1,OSBPL8,DNAJC7,KPNA1,ESYT1,TUBG1,COPS5,HM13,SLC25A46 |
| 3.051e-04 | -8.09 | DCAF4L2 (DDB1 and CUL4 associated factor 4 like 2) | protein interactions | 138009 | 40 | 22 | 19454 | 5460 |
HSPA8,TRIM21,HSPD1,PABPC1,CCT8,HNRNPA2B1,PDRG1,COPS4,HSPA5,HNRNPK,H1-3,GSTP1,MYL6,PRMT5,COPS2,COPS7B,TCP1,CFL1,COPS5,PRDX1,CCT2,PPM1B |
| 3.051e-04 | -8.09 | DDHD2 (DDHD domain containing 2) | protein interactions | 23259 | 40 | 22 | 19454 | 5460 |
CSK,EMILIN1,LAMP2,RAB11A,MTCH2,HP,LAMTOR1,BLVRA,RHOG,VPS33A,DNAJC7,TMT1A,RCCD1,HSD17B11,GSK3A,DERL1,RAB5A,ALB,RAPGEF5,TF,CHI3L1,DYRK1A |
| 3.051e-04 | -8.09 | KRBA1 (KRAB-A domain containing 1) | protein interactions | 84626 | 40 | 22 | 19454 | 5460 |
FBXO22,TRIM37,TRIM52,TBCCD1,TFPT,FBLN5,MAEA,GSK3A,EFNB1,TRIM27,P4HA2,IFT172,P3H1,TCEAL9,PNMA2,CDC16,ZMYND19,CUL3,PRMT2,TOMM40,CCL3,FNTB |
| 3.051e-04 | -8.09 | IFRD1 (interferon related developmental regulator 1) | protein interactions | 3475 | 40 | 22 | 19454 | 5460 |
RIGI,HAPSTR1,BSCL2,EP300,RNF113A,RPA3,MEF2C,IFRD1,RPA2,COMTD1,FAM234A,FZR1,HNRNPL,LMBR1L,EIF2AK2,RIT1,PDE4B,YWHAG,CSNK2A1,CTNNB1,WWP2,GPR17 |
| 3.057e-04 | -8.09 | MOB4 (MOB family member 4, phocein) | protein interactions | 25843 | 147 | 61 | 19454 | 5460 |
TNIK,RAB35,PPP2CB,TRAF3IP3,TCP1,SLMAP,ELK1,STK3,CCT7,STOML2,STK4,NME2,PDCD10,RB1CC1,CCT8,SIKE1,MYO1B,SLC39A7,AGA,CAMK2G,PSMA5,KRAS,SNAP29,CCT5,DDX39A,ACTN4,PPP2R1A,S100A6,RMDN3,PSMC5,CAB39,TMOD3,DYNLL1,RPGRIP1L,EGLN2,LRIF1,UBE2V2,ESR2,RAB2A,FGFR1OP2,CCDC85B,ISCA2,CCT2,MED10,STK24,ATG3,MYO6,NAPA,CRMP1,STK11,RIT1,DDX39B,SF3B1,STK26,SNX24,B9D2,ATG16L1,TIMM13,RPA2,MYL6,MED31 |
| 3.062e-04 | -8.09 | CCL13 (C-C motif chemokine ligand 13) | protein interactions | 6357 | 28 | 17 | 19454 | 5460 |
CCR2,CXCL11,CCL2,CXCL9,CXCL10,CCL8,CCR3,CCR5,CXCL14,HNRNPH3,CCL21,CXCL12,XCL1,CCL24,CCL11,CCL5,CCL28 |
| 3.062e-04 | -8.09 | FAM13A (family with sequence similarity 13 member A) | protein interactions | 10144 | 28 | 17 | 19454 | 5460 |
AHCYL1,VIRMA,UNC119B,MPP1,YES1,HNRNPL,PPP2R5E,PCNA,TBCCD1,YWHAB,YWHAZ,MYO6,YWHAG,PPP2R1A,YWHAH,PPP2R5A,SFN |
| 3.062e-04 | -8.09 | PLAC9 (placenta associated 9) | protein interactions | 219348 | 28 | 17 | 19454 | 5460 |
MACO1,EMILIN1,EMC4,SNAPIN,EMC6,GPRASP2,TENM3,GPD2,SRPRA,ATP2B4,EFNB1,FBXO11,RAPGEF5,SPPL3,SSNA1,ABHD12,HSPA5 |
| 3.062e-04 | -8.09 | ECT2L (epithelial cell transforming 2 like) | protein interactions | 345930 | 28 | 17 | 19454 | 5460 |
CHP1,SKP1,FARSA,INA,PSMA5,TTC9C,CTNNA1,ZNF436,TMEM263,MLLT11,HAX1,NEFL,MRPL10,TOMM40,HNRNPC,HMGA1,GSTM3 |
| 3.067e-04 | -8.09 | SLC16A2 (solute carrier family 16 member 2) | protein interactions | 6567 | 45 | 24 | 19454 | 5460 |
QNG1,PLP1,VEGFA,VAMP3,SYNGR1,ANKRD46,TSPO2,EFNA5,SLC38A7,SLC39A13,BTN2A2,JAGN1,SLC39A9,TMEM254,TMEM60,ADIPOQ,CCL2,LEPROTL1,TOMM6,FAM234A,MFSD6,SMCO4,CYB5B,FAM3C |
| 3.067e-04 | -8.09 | MEF2C (myocyte enhancer factor 2C) | protein interactions | 4208 | 45 | 24 | 19454 | 5460 |
MEF2A,RIGI,HDAC5,EP300,MEF2C,IFRD1,CDK1,VGLL2,SOX2,PLA2G12A,TULP3,SPTBN1,TWIST2,PRNP,UBE2I,VGLL4,SP1,SMAD2,YWHAZ,COPS5,CSNK2A1,MEF2B,MYC,CCNB1 |
| 3.067e-04 | -8.09 | ARHGAP31 (Rho GTPase activating protein 31) | protein interactions | 57514 | 45 | 24 | 19454 | 5460 |
PCNA,TMEM263,CSTB,ZYX,MRPS17,ARF4,TRIM37,HMGB1,KRAS,CHCHD2,PRDX3,CDC42,PPIF,MRPL10,DHRS7B,SF3B5,TIMM23,HACD3,ARF1,VIRMA,SMURF1,PRDX2,XPO1,CFL1 |
| 3.097e-04 | -8.08 | SNX27 (sorting nexin 27) | protein interactions | 81609 | 489 | 172 | 19454 | 5460 |
OTULIN,BPIFB1,TMEM45A,FOXP4,SEMA4C,ATP5F1D,TNF,UBE3A,SKA1,VPS26B,SRSF8,JAK1,ZYX,HSPD1,TRIP4,AKT2,LYZ,PPM1B,FIG4,BABAM1,VPS26A,FRA10AC1,UBXN6,ATG9A,SRSF10,CACYBP,SNX1,NYAP2,SNX2,ETF1,PPP1CB,GKAP1,MAPKAPK5,FAM234A,POLA2,TACR3,ATAD1,NSFL1C,NPTN,FAS,MRPL16,PRPF31,PKP4,FCHSD2,USP5,PTPRQ,SPINDOC,TAB1,MTM1,LRRC1,SERPINA1,JCHAIN,PPP4C,MTARC2,DDX39A,METTL26,NOC4L,TF,BRD3,SLC2A1,ASNSD1,RPL35A,ARF6,STOM,CNP,PIP5K1A,TMEM209,PFKFB2,TTR,RPA3,SMAD2,IVNS1ABP,PIP4K2C,STK38L,SH3BP4,SLC25A4,PTEN,SPIN3,ALB,CFAP298,ODR4,TMEM74,TRIM27,CTNNA1,CARTPT,SERPINA3,DHX38,ZBED1,FBXO3,ANKRD50,NT5C2,BTF3L4,TBC1D5,YWHAG,PPFIBP1,SUMO2,AFTPH,PRCC,RBM5,PIH1D1,EIF4B,LMBRD2,PAFAH1B1,USP6NL,SAP18,ZBTB5,PITHD1,ADRB2,LCN1,DNAJB6,KIF3C,CCL25,LAMTOR1,SLC1A3,CHRDL1,PSMA4,MYC,NLGN2,ESR2,ACAP2,KBTBD2,STAT1,FAM83B,TAB2,CAPZA2,GPD2,IPO8,SNAP29,CAPZA1,REXO2,SLC16A1,ATP2B4,EIF1AD,PALM2AKAP2,USP15,MAP4,LSM3,SHC1,SLITRK5,BCL10,TSEN34,HP,SCGB1D1,MTMR12,TCEANC2,KCTD3,GATAD1,ADD1,NDUFB4,LEMD3,CYC1,GIT2,SSR1,RPA2,CFTR,SMYD3,CLU,GREM2,STK38,RPS15,ELOF1,UBE2H,SNX5,CALU,DTL,LACRT,ATP1B3,CHPF,MTPN,ROCK1,SEC61A1,TRAF7 |
| 3.115e-04 | -8.07 | MTPAP (mitochondrial poly(A) polymerase) | protein interactions | 55149 | 150 | 62 | 19454 | 5460 |
PEX3,SKIC8,RHOG,EID1,LAMP3,DDRGK1,ACTL6B,NFKB1,GRSF1,MTRF1,WWP2,FAM174A,SURF6,RHOH,YBEY,GATD3,RAC2,FAHD1,SSBP1,GEMIN7,DCAF8L2,PDHA1,SOX2,MGARP,AZI2,RAF1,TBK1,MRPL11,FASTKD5,IMMP2L,ATG4A,ADIPOQ,COX8A,MAPRE1,LGALS8,LMNB1,EMILIN1,MYC,CUL3,PRMT6,PARL,ESR2,RPL10,DYNLL1,RHOJ,PRKRA,OPTN,CCNF,HECTD1,MTRES1,RPA2,FOXS1,GTF2IRD1,RND2,CDC42,ATG16L1,NF2,PGK1,CLK1,THBS3,RNF113A,GFM1 |
| 3.118e-04 | -8.07 | THOC5 (THO complex subunit 5) | protein interactions | 8563 | 124 | 53 | 19454 | 5460 |
TNFAIP6,RPL6,CSNK2A1,SMAD4,DDX23,SNRNP70,LSM3,HSPB1,THOC2,ALYREF,PSMB1,SPPL3,RPS10,TOP1,PRNP,THOC1,RAF1,E2F4,KIF1C,DDX39A,UBR7,NUPR1,ZC3H11A,IMP4,POLDIP3,SSRP1,SNRPB,FYTTD1,CHTOP,RIT1,UBE2H,THOC6,OXTR,EIF4A3,GTF2F1,MAGOHB,ESR2,RPL22,SF3A1,RPL27A,ZC3H14,MRPL12,PSMB7,RPA2,PRKCA,THOC3,RPA3,DDX39B,SNRPA,RFC4,STAU1,ZC3H15,AATF |
| 3.118e-04 | -8.07 | CDC42EP1 (CDC42 effector protein 1) | protein interactions | 11135 | 124 | 53 | 19454 | 5460 |
ARF6,RHOH,DIRAS3,EGLN3,CAV1,HRAS,RAB35,EEF1AKMT3,RAC2,RHOG,YWHAB,UBXN6,LAMP2,DPP4,MDFI,RAB5C,FAM174A,FAM20C,LAMP3,YWHAH,COMMD5,XPO1,YWHAG,KRAS,CDK20,CA10,PLSCR1,FHL3,TUBB4B,RND3,STK16,KBTBD4,E2F4,MGARP,RHOJ,MAD2L2,LAMTOR1,RHOB,YWHAZ,KLK5,ARMC7,RAB2A,CUL3,SFN,DNAJC5,STX7,RHOU,TIMP3,SAT1,ARL15,RND2,TSHR,CDC42 |
| 3.118e-04 | -8.07 | TNK2 (tyrosine kinase non receptor 2) | protein interactions | 10188 | 124 | 53 | 19454 | 5460 |
PIK3R3,CSK,AKT1,AR,MCM3,TUFM,BAG3,ATP5F1A,YWHAZ,CCT2,HSP90AA1,NTRK3,CTTN,SIAH1,YES1,HECW1,STAT1,SRC,SMURF1,HSH2D,ATG16L1,CDC42,RASGEF1C,FGFR1,SQSTM1,EP300,FABP4,WWP2,PIK3R1,ATG9A,SIAH2,YWHAG,NCK1,CDKN1B,HAX1,SH2D1A,SOCS4,TCP1,HNRNPL,VTI1B,NUF2,HSP90AB1,LCP2,CCT5,TP53,TOP3B,ISG15,CRKL,CCT8,SLC25A5,HSPD1,NTRK2,ZBTB16 |
| 3.120e-04 | -8.07 | KRT18 (keratin 18) | protein interactions | 3875 | 391 | 141 | 19454 | 5460 |
FASTKD5,KPNA2,HNRNPK,ERO1A,EFHC1,SLC25A11,SLC25A10,RAB1A,MAP1B,NUPR1,PSMC3,SERPINA1,NEFL,DDX39A,TBK1,FBP1,G6PD,CAV1,CDC5L,CDK9,CD4,TES,RCHY1,SSBP1,HRAS,PEX5L,SSX2IP,SHC1,H2AC4,SNRNP70,TUBG1,HDAC6,ORC5,DPP4,HSPA5,EIF4E,LDOC1,RNF113A,PML,RPA3,BAP1,HECTD1,HAUS2,TRIM36,HEXIM1,PRKCA,GIT2,METTL14,RPA2,CDK1,CFTR,CCND1,VIRMA,CCDC42,CEP97,PRKCE,RPGRIP1L,TXN,RTRAF,GANAB,CTNNA1,TNFRSF1B,UBE2H,DEDD,CCHCR1,BICD2,CCDC22,SPOP,TUFM,PPP1CC,AR,PTPN11,SEC13,MAT2A,RFC2,TRIM37,TRIM26,LASP1,G3BP1,KRAS,TNF,RTCB,PABPC1,HGS,PLS3,FAF2,PPP2R1A,HEXA,TXNRD1,RAF1,MACO1,DHX15,CNTROB,TRMT61A,SNX2,INA,KRT8,TSG101,XPO5,EED,HSPB1,ARMC8,YWHAB,DDX1,CBL,RB1CC1,PPM1B,YWHAH,YWHAG,NSFL1C,FXR2,UCHL3,CNTN1,EP300,TXNL1,HSPA8,CCNI,WBP2,DNAJC3,PIH1D1,CNDP2,PAK2,PRDX3,DYNLL1,ACTB,FAM83B,LMBR1L,DNAJB6,EXOC8,SP1,BRCA1,YWHAZ,CCDC85B,BTF3,HMGCS1,PDE4B,PSMD1,CUL3,SFN,HNRNPC,MYC |
| 3.124e-04 | -8.07 | negative regulation of vascular associated smooth muscle cell migration | biological process | GO:1904753 | 27 | 17 | 18204 | 5365 |
MIR223,MIR214,NFE2L2,MIR137,MIR638,ADIPOQ,MIR182,MIR1298,MIRLET7B,MIR503,MIR218-1,MIR15A,MEF2C,MIR34A,MIR424,MIR21,MIR140 |
| 3.124e-04 | -8.07 | cotranslational protein targeting to membrane | biological process | GO:0006613 | 27 | 17 | 18204 | 5365 |
TRAM1,SEC61A1,SRPRB,SRP54,SEC62,SRP72,TRAM2,TRAM1L1,SEC61B,SRPRA,SRP14,SSR3,SEC61A2,SSR2,SEC63,SSR1,ZFAND2B |
| 3.136e-04 | -8.07 | MYO9A (myosin IXA) | protein interactions | 4649 | 93 | 42 | 19454 | 5460 |
HNRNPL,ATP5PD,APEX1,VIRMA,KCNA2,CCNF,FUBP3,LURAP1,DKK3,RTRAF,GSK3A,CKB,YWHAZ,RHOB,COP1,YWHAB,MYC,CREB3,UBXN6,CDC16,MOV10,SFN,YWHAG,YWHAH,SLC31A1,CRYL1,HSPE1,TRIM52,MRPS17,NHP2,UNC45A,MRFAP1L1,P4HA2,HSD17B10,PNMA2,CHMP4C,CAPN2,SNRPE,RAF1,TP53,CDC42,SOX2 |
| 3.136e-04 | -8.07 | IRF7 (interferon regulatory factor 7) | protein interactions | 3665 | 93 | 42 | 19454 | 5460 |
AIP,SMAD3,SUMO3,TCP1,SUMO2,POLR2B,CCT7,NMI,TNFAIP3,CREBBP,ZNF24,MCM3,IQSEC1,MLF2,CCT2,SMAD4,TRAF6,SMAD2,VPS4A,MAP1B,MYD88,CCT8,PML,IRF3,TRIM21,MAVS,EP300,IRF7,ACADS,KPNA2,TICAM1,TICAM2,RIGI,CXXC1,CCDC47,RAF1,TBK1,CCT5,TANK,TP53,SOCS3,CBX3 |
| 3.136e-04 | -8.07 | COQ2 (coenzyme Q2, polyprenyltransferase) | protein interactions | 27235 | 93 | 42 | 19454 | 5460 |
H2AC4,YWHAZ,H1-10,H2AZ2,PPM1B,NDUFAF2,LDHB,STOML2,CHCHD3,DKC1,TXN,SLC25A4,RB1,MRPL13,ARF1,SSBP1,VDAC2,EIF4A3,ALYREF,ILF2,SLC25A3,COX6C,JUP,PDHA1,IDH2,AURKAIP1,PCK2,MRPL22,MARS1,PDHB,THRAP3,BOLA2B,CLEC12B,ETFA,HSPE1,PGK1,ATP5F1E,SLC25A5,RPL27,BAP1,SCYL2,SFXN1 |
| 3.150e-04 | -8.06 | negative regulation of nervous system development | biological process | GO:0051961 | 138 | 60 | 18204 | 5365 |
CERS2,TP53,DLX1,BRINP1,TNF,MT3,CTNNB1,NKX6-2,IL6,ID4,LDLR,DKK1,CDK5,SPP1,IL1B,YWHAH,PPP3CA,WNT7A,THY1,PROX1,DRD3,GPR37L1,DUSP10,CCL11,SEMA5A,NOG,HDAC6,TRIM46,MIR181C,BMPR1A,NRP1,MECP2,PTEN,PAX6,MIR137,TRIM11,RGMA,LHX2,NF2,RB1,FGF13,B2M,TNR,ELAPOR2,CTNNA1,TLR2,TSPO,BTG2,NR2E1,RTN4,IFRD1,PTN,PSEN1,MIR146A,CTDSP1,RNF10,DICER1,SYT4,CBLN1,F2 |
| 3.151e-04 | -8.06 | SUCLG2 (succinate-CoA ligase GDP-forming subunit beta) | protein interactions | 8801 | 107 | 47 | 19454 | 5460 |
RAF1,CMPK1,CCS,FAF2,EZH2,RPN1,PDHA1,ABCE1,ETFA,IMMP2L,ABHD10,NDUFV2,ACP6,SMAD4,GSTO1,HSPB1,AIFM1,COX4I1,ATP6V1A,SDHAF2,GATD3,MRPL50,EGLN3,PAFAH1B1,SEC22B,CFTR,MRPL12,STXBP1,HSP90B1,SOD1,IDH3A,HSPA8,PRDX6,HSCB,OXCT1,GRPEL1,RAB2A,CTSD,RNASET2,MYC,PMPCA,CUL3,CFL2,GMPS,CTTN,LDHA,TENT5C |
| 3.151e-04 | -8.06 | POLR3C (RNA polymerase III subunit C) | protein interactions | 10623 | 107 | 47 | 19454 | 5460 |
KRAS,KPNA2,NOC4L,GTF3C3,PAX6,ENKD1,PICK1,CDK8,CBX3,RPN1,DISC1,RBPJ,TRMT1L,PNMA5,TRAF2,KIAA0408,CD2BP2,POLR3F,TNR,POLR2L,KPNA1,BRD3,CSNK2A1,POLR3GL,STAU1,COIL,RPA3,NUP50,EP300,LMNA,RPA2,POLR1D,GTF3C4,SNRNP40,ROCK1,VRTN,TRIM27,POLR3B,POLR2F,POLR3H,GADD45B,NCKIPSD,RIT1,MAF1,MYC,SUB1,KPNA6 |
| 3.152e-04 | -8.06 | GPD2 (glycerol-3-phosphate dehydrogenase 2) | protein interactions | 2820 | 82 | 38 | 19454 | 5460 |
CD63,COX4I1,PLAC9,AIFM1,CCNF,OPTN,COQ8A,SDHB,TRAPPC10,PARL,VIRMA,SLC25A12,UQCRQ,TSPAN10,MDFI,ACO2,MYC,HSD17B1,AGR2,SMAD4,HAX1,NRP1,SFXN1,RPA3,GHRL,HSPA8,STAU1,SLC25A51,NF2,MTCH2,RAF1,APOO,FAF2,NPY2R,AQP3,RPA2,PLD3,CRELD1 |
| 3.152e-04 | -8.06 | ZNF451 (zinc finger protein 451) | protein interactions | 26036 | 82 | 38 | 19454 | 5460 |
COP1,RNF40,PCBD1,SUV39H1,AR,CREBBP,CSK,MYC,CUL3,PIK3R3,VIRMA,CDC5L,PRNP,SUMO2,SUMO3,SNRNP40,ZMYM2,UBE2I,CREB1,EIF4A3,RPA2,CBX3,RAF1,TP53,SUMO1,PIAS1,PTGES3,CLU,FXR2,ZBED1,KDM1A,NUP50,SNIP1,S100B,CPTP,PML,TOP2B,ZNF451 |
| 3.152e-04 | -8.06 | OSBPL9 (oxysterol binding protein like 9) | protein interactions | 114883 | 82 | 38 | 19454 | 5460 |
VAPB,RPA2,FGFR1,SSR1,CFAP36,TP53,SEC62,BORCS6,KRAS,STX7,SACM1L,RIGI,H2BC14,RPA3,TMT1A,POLD2,BLOC1S2,IGF1R,RAB9A,RAB5A,LAMTOR1,CYP1A1,HSPB1,LAMP2,RAB11A,RAB5C,LAMP3,ISCA2,HNRNPL,COPE,RHOH,KBTBD6,RAB35,CCNF,PTPN1,FBXO32,RAC2,SEC61B |
| 3.152e-04 | -8.06 | RNF19B (ring finger protein 19B) | protein interactions | 127544 | 82 | 38 | 19454 | 5460 |
PIK3R1,DNAJB2,CLEC1A,TMEM208,MBLAC2,WDR11,PPP1CC,WDR20,HSP90AA1,TMEM100,USP15,FAM91A1,CDIPT,CIB2,MFSD5,SEC23A,USP46,PRNP,DIRAS3,UBB,UBE2L3,GOSR2,SELENOK,SEC22A,ZMYM4,LGR4,ST7,TMEM31,PIK3CA,MEST,HSDL1,NEK9,TNF,UBE2D3,PIK3R2,TOLLIP,AP1M1,SACM1L |
| 3.170e-04 | -8.06 | CRY1 (cryptochrome circadian regulator 1) | protein interactions | 1407 | 153 | 63 | 19454 | 5460 |
YWHAZ,GMPS,MCM4,MCM3,ATP5F1A,PPAT,TUBB,MATR3,EIF4A2,TXN,RPL10,UBB,RPS3,CREB1,PPP2R5E,CSNK2B,PRMT5,AP2M1,PSMC5,RARS1,WDR77,RPS14,PSMC4,DET1,MARS1,SKP1,HSPA5,PSMC1,XRCC5,HNRNPH2,CRY1,YWHAB,USP2,PRDX1,MDFI,PSMD3,YWHAH,XPO1,CSNK2A1,TCP1,SNRPD3,HNRNPL,PPP2CB,SYNCRIP,NDUFS3,FBXL3,CSNK1E,EEF2,TRAF2,EEF1A1,PPP2R1A,RUVBL1,HNRNPK,HNRNPF,HUWE1,PRDX4,RPS27A,CCT8,PABPC1,SCYL2,PLSCR1,SLC25A5,RUVBL2 |
| 3.170e-04 | -8.06 | MTG1 (mitochondrial ribosome associated GTPase 1) | protein interactions | 92170 | 153 | 63 | 19454 | 5460 |
YBEY,MRPS9,MRPS23,MRPL24,MALSU1,NDUFS8,MRPL50,PRNP,MRPL9,MRPS35,GRSF1,MRPS26,PICK1,MRPS18B,ATP5PF,PREPL,MRPL52,HSPD1,HNRNPDL,ETFA,KRAS,MRPS33,BCS1L,MRPL11,NDUFA2,ATP5PB,MRPL51,MRPL49,NDUFA12,PDHA1,NDUFS3,MRPL13,MRPS28,DLST,MRPL53,TACO1,NDUFAF4,RHOJ,MRPL23,MRPL16,PMPCA,NDUFAF2,OAT,MRPS25,MRPS16,DLAT,POLDIP2,MRPS7,FTL,MRPL41,FBXW7,GRPR,MRPL17,PDHB,NDUFS2,MRPL12,CDC42,HCST,RBFOX2,COQ8B,MTRES1,NDUFA5,MRPS34 |
| 3.174e-04 | -8.06 | regulation of immunoglobulin production | biological process | GO:0002637 | 76 | 37 | 18204 | 5365 |
XCL1,IL10,HMCES,TNF,MAD2L2,IL5,IL13,TFRC,EXOSC3,PHB1,CD86,CGAS,SHLD1,CD28,TRAF2,IL21,KMT5B,IL6,NDFIP1,CD40,IL4,TMBIM6,FOXP3,TRAF6,BCL6,SASH3,XBP1,TNFSF13,TLR9,CD40LG,MZB1,DNAJB9,IL2,VAMP3,STAT6,FCGR2B,PHB2 |
| 3.177e-04 | -8.05 | SMC1A (structural maintenance of chromosomes 1A) | protein interactions | 8243 | 388 | 140 | 19454 | 5460 |
KRAS,RBBP7,CDK20,MCM6,GTF3C3,RAD21,PAX6,NEK9,ARGLU1,HNRNPA2B1,TUBB4B,VPS33A,EZH2,CHMP4C,HDAC11,POLR2C,MTA2,MOB3C,RNF126,TOP3B,TUBA1A,SOX2,SAP30,ELF1,SUMO2,EGLN3,NUF2,DNM2,PHB1,EED,GANC,RB1CC1,PEX3,MGMT,LHX2,PRPF19,FAM174A,WWP2,NDC80,HAND2,STAU1,DUSP26,DDI1,COIL,FTL,HDAC5,SF3B1,HSPA8,EP300,CFDP1,ARMCX3,EMC9,PIH1D1,MTF1,BET1,NEK7,MATR3,TRIM29,RBBP4,ESR2,MAD2L2,RSRC1,NFKBIA,ZNF174,ANAPC2,GCC1,KIAA1191,YWHAZ,BRCA1,LSM14B,RIT1,MYC,USP13,CUL3,PRPF31,MCM4,CASP4,H3C1,THRAP3,PHF1,VTA1,MSH6,MDC1,SFXN1,ABCE1,RING1,CDK8,CDK4,MGARP,H2AX,EEF1A1,AURKAIP1,MRPL50,CITED1,CDC5L,SSU72,EEF1AKMT3,MGME1,OR5B3,BECN1,USP15,SAT2,NF2,SMC4,FBXW7,MBD3,WFDC5,ATG4C,BAP1,RPA3,IRF3,NBN,DERL1,RAB9A,RPA2,LMNA,MET,HAUS2,ATG16L1,AKR7A2,GTF3C4,KLF12,COPE,NDN,SNX3,BCCIP,VIRMA,CCNF,TUBA1B,GANAB,PTPMT1,TRIM24,ALB,IVNS1ABP,UBE2H,SMARCA5,EMILIN1,SUB1,AR,TUFM |
| 3.186e-04 | -8.05 | NOTCH1 (notch receptor 1) | protein interactions | 4851 | 338 | 124 | 19454 | 5460 |
CDC42,CCN3,WWP1,SQSTM1,EGFL7,RHOU,PSEN2,TRIM3,KDM1A,STK38,USP8,FBXW7,RUNX1,IFNAR1,SMARCA5,VPS39,RAB2A,TRIM32,AKT1,HEY2,RTRAF,PTEN,STUB1,ROCK1,VIRMA,STC1,RHOJ,CLEC2B,FBP1,FURIN,PIK3CA,RING1,LPAR2,PSEN1,NFKB1,USP2,IGFBP4,USP15,ATP6V1D,SMCHD1,EXT1,RAC2,RB1,ELSPBP1,HRAS,HCLS1,SMAD3,STX6,MDM2,CAV1,ZBTB2,ARF6,ARL6IP5,CAND1,RND2,LNX2,CLDN4,NOTCH2,MED23,EP300,RAB5A,RFC4,WNT2,STX7,RANBP10,CNTN1,RNF40,OTUD7B,MCM3,RAB11A,CUL3,IKZF2,ILK,LAMTOR1,KIAA1191,RHOB,SEC61B,ERH,SIAH1,TAB1,RBBP4,PPP2R1A,KIF2A,B3GALT4,TOP3B,RBPJ,RND3,HGS,RAB4A,PIK3CG,MEF2C,TOP2B,CCT8,FANCG,FLOT1,KRAS,TRIM37,DLK2,WDR11,CTNNB1,PRPF19,IFI16,ZBED4,CFC1,RAB5C,CDC23,CBL,SMAD9,ARMC8,RHOG,WDR12,XPO5,GJA1,MAP1LC3A,TRAPPC10,RAB35,WDR6,PPP2CB,CEP57L1,DIRAS3,HSP90AB1,DHX15,KCTD10,RHOH |
| 3.202e-04 | -8.05 | nuclear envelope | cellular component | GO:0005635 | 498 | 180 | 19108 | 5553 |
DNAJB2,CHMP4C,ROGDI,ANXA4,MYO6,PTGDS,MATR3,CHMP1A,FZR1,BOK,GAPDH,NUP35,NUP107,KPNA2,DTL,ABCF1,ATRAID,CCAR1,SIGMAR1,CREB3L4,ALOX5AP,CHMP1B,MX1,RBM15B,SLC52A3,ARL6IP6,FAM156A,CHMP5,BNIP3L,DMPK,TMPO,BICD2,FAM169A,EI24,MINDY3,VPS4B,NUP42,TNPO3,PLPP6,CACYBP,CCNI,MX2,INPP4A,IL15RA,KLK6,NUP62,TRIM27,RBMX2,SMAD1,NOS1AP,H2BW1,TMEM33,HACD3,BCL2L1,PSEN1,DNAJC1,TMEM168,CASC3,TOR1AIP2,GCHFR,MGST3,MTDH,DNAJC2,SYNE4,LBR,GNAQ,RETSAT,STX1A,WDR3,SUMO1,CHMP2A,THAP7,BRAP,TMEM170A,FAF1,ENO1,CD2AP,CETN2,TNKS2,DES,CD38,XPO1,VPS4A,RANBP1,LYPLA1,KPNA1,PAK5,GPX4,TMEM38B,KCNJ11,TOR3A,UNC50,CBX3,ZBED1,CETN3,PARP11,TENT4A,PSEN2,SRSF1,CPNE1,CHMP2B,ZMPSTE24,LEMD3,OSBPL8,TNKS,RAC2,NXT2,CDK4,MACO1,TMEM147,NUDT9,MRPS23,MAD2L1,TMEM176B,NOC4L,PLCB1,NUP153,KCNH1,TOR4A,GTF3C3,SEC13,TMEM209,APEH,TOR1B,PAFAH1B1,PLAAT3,NUP37,RRM1,PTGES,SDCBP,C9orf72,LMNA,BAX,AGPAT5,ADRA1A,MYORG,MTMR6,SURF4,LMNB1,NXT1,TERB2,GNAZ,ENY2,CPTP,RTN4,S100A6,CBX5,RAN,NUP50,NUDT1,BANF1,IPO8,UBE2I,TRA2B,RTCB,NLRP6,SMAD3,IFI27,XPOT,OTULINL,MNS1,SEPHS1,TUBB,FBXW11,ELAVL4,RB1CC1,MGST2,CCND1,TMEM97,HAX1,NRM,MAD2L1BP,TMX4,CALR,TOR2A,PRICKLE2,WTAP,PRNP,CSE1L,GLE1 |
| 3.202e-04 | -8.05 | PPP1CB (protein phosphatase 1 catalytic subunit beta) | protein interactions | 5500 | 448 | 159 | 19454 | 5460 |
CSRNP1,CORO1C,WDR82,EED,GYS1,RAB35,WDR44,DHX15,SPTAN1,OSBP,SNX1,HNRNPL,CTNNB1,DDRGK1,WWP2,ARMC8,PPP1R11,HNRNPD,RASSF8,PSMD10,RPAP3,MYO1B,HNRNPA2B1,CCT8,SSRP1,ASF1A,HNRNPF,KRAS,TNF,ACTN4,ISG15,E2F4,MAX,RAF1,SMARCB1,EZH2,LRRC1,CPSF1,USP5,ESR2,GNB1,PPP1R3C,CHCHD3,TSN,ACTB,MATR3,MCM3,BTF3,CUL3,PAPOLA,ACO2,APOBEC3B,MYC,RIT1,RHOB,BRCA1,MYO6,PPP1R16A,YAF2,STK26,DDX5,NMRAL1,SPECC1L,CCND3,PSMC1,MCMBP,PGRMC1,WDR77,NCOA5,PIH1D1,CSNK1A1,MED23,PAK2,RB1,TES,DSTN,SFRP1,PTPN1,SSU72,TOP1,PPP1R18,FZR1,DAG1,TPM3,NFKB1,MAP4,H2AC4,DHX9,ABCE1,PSME1,PQBP1,RAB1A,PALM2AKAP2,PPP1R12A,CAPZA1,PDRG1,DNAAF10,TMEM33,PPP1R27,H3C1,UBXN2B,LBR,EEF1A1,CD2BP2,WBP11,TAF2,RNF8,NUPR1,ACTR2,CAPZA2,CSNK2B,GSK3A,CTTN,CCNF,PPP1R10,ADRM1,YES1,NDN,TMOD3,DAPK3,PPP1CC,RACGAP1,AR,ST13,NONO,CFL2,ARHGAP21,FBXO7,CFL1,CCNB1,AKT1,UBE2H,MAPRE1,AP2A1,SPOP,TNFAIP1,ARPC2,CLK1,PML,SIRT7,RPA3,BAP1,AATF,FBXW7,PPP1R2,GTF2I,NEK2,CCND1,PPP1R8,SPTBN1,ATG16L1,PSMC4,SHOC2,HNRNPH3,HEXIM1,TMOD1,ZNF326,RPA2,TOX4 |
| 3.204e-04 | -8.05 | positive regulation of response to biotic stimulus | biological process | GO:0002833 | 314 | 121 | 18204 | 5365 |
SH2D1A,IRAK4,TRIM3,MYD88,PQBP1,RTN4,IFIH1,IFNK,TLR9,ZNRF1,IFI16,TLR8,LILRA2,TRIM15,NMI,CLEC6A,TAB1,MAVS,IKBKB,CAV1,IFNB1,TYROBP,RIGI,SIN3A,TICAM1,TLR1,ATAT1,CD36,POLR3F,MATR3,IL12A,SRC,CD274,HSPD1,BCL10,MIF,TLR4,FLOT1,PELI1,NONO,NECTIN2,RNF34,HSP90AA1,USP15,IRF3,PHB2,TOMM70,HEXIM1,IL12B,POLR3B,UBE2K,TLR3,CCL5,IL17F,NEK7,RSAD2,CLEC7A,IL21,TICAM2,TLR10,NLRP3,TRAF6,TLR2,CD14,PRKCA,TMEM126A,MAPKAPK3,NINJ1,XRCC5,TBK1,PLSCR1,KLRD1,TIFA,PAK2,TLR5,IFI35,BECN1,PLA2G5,TIRAP,LSM14A,PSPC1,TLR7,IRF7,NLRP6,TASL,MAP2K6,OAS1,TRAF3IP3,CGAS,KCNJ8,PRKCE,LACC1,OTULIN,DHX9,MBL2,NLRP1,PTPN22,HMGB1,CD1D,SYK,CD226,TRIM5,CREBBP,PYCARD,TLR6,KLK3,EMILIN1,NCR3,CLPB,FCN2,TNF,EP300,NFKBIA,LY96,TRIM6,PHB1,KLK5,TRIM62,PIK3AP1,KLRC2,TNFAIP3 |
| 3.205e-04 | -8.05 | ACTN4 (actinin alpha 4) | protein interactions | 81 | 363 | 132 | 19454 | 5460 |
HSPA5,PIAS1,MEF2A,HMGB1,AIF1L,ARPC2,TRIM3,MYH2,IDH3A,SIRT7,BAP1,INPPL1,RPA3,SOD1,CYC1,UBE2M,RPLP0,IDH2,RPA2,CFTR,ATG16L1,SRC,VIRMA,TXN,DAPK1,CTSB,KCTD9,PPP2R5E,UBASH3B,SGTA,MOB4,GSK3A,CTTN,PSMA6,RPS3,CCNF,MAPRE1,UBE2H,NRP1,CDC73,TRIM23,SPOP,AR,ST13,NCAPG2,USP14,PTPN11,CAPZA1,WASL,KPNA2,HUWE1,CAMK2G,DHX9,PPP1R12A,FURIN,NUPR1,ILF2,CAPZA2,ACTR2,TFRC,INSIG2,TP53,CDK9,PRNP,TES,SYNCRIP,SHC1,SMCHD1,PTGER4,TPM3,GAPDH,CD81,HDAC6,PPM1D,DPP4,COIL,PSMA3,HDAC5,NMRAL1,HSPA8,SPECC1L,TMEM106B,PPP1CB,USP6NL,ACTB,TENT5C,STAT1,RPS9,PRMT5,ICAM1,CKB,GGH,PDE4B,BTF3,CUL3,HNRNPAB,MYC,NFYA,ACO2,SAR1B,AHCYL1,TRIM37,PSMA1,RBBP7,TRIM21,MYO1B,HNRNPA2B1,PABPC1,ZYX,HGS,CYB5B,PDHA1,CHMP4C,EZH2,ISG15,SOX2,VDR,TOP3B,HSP90AB1,OSBP,HNRNPL,TSG101,MYEF2,PSMB5,FOLR1,HSPB1,HNRNPD,AGR2,CTNNB1,YWHAG,HNRNPA1,SYNJ2BP |
| 3.219e-04 | -8.04 | regulation of primary metabolic process | biological process | GO:0080090 | 5680 | 1772 | 18204 | 5365 |
LMO4,TNFSF13,CREBZF,RIOK2,EIF2AK2,MIR221,ATP5IF1,PSMC3,SS18,NCOA5,CARTPT,UBE2N,SLC8A1,RRN3,MIR497,PTEN,JAK2,MCPH1,LMO2,MED31,MORF4L1,FBXL19,LRP6,USP3,CAND1,STAT1,CRY1,DVL2,LACC1,SMCHD1,ABCE1,DEFB114,UBE2V1,MIR1271,EID2B,SERPIND1,NOP53,TNFSF15,RNF128,INO80E,SMAD4,PDCD10,MAGOH,DR1,SNX5,PACSIN3,KARS1,EIF3D,NAA16,HYAL2,SHLD1,CTNNB1,SP2,SLC1A1,CYFIP2,COPS7B,GPT,EMP2,SMURF1,MOB3C,DNM2,NOS1AP,UBE2B,TSPAN17,RHOBTB3,CREBL2,NGDN,SYNCRIP,ELP6,WDR82,ECD,CKS2,RPS2,MIR21,MED29,IFI27,SERPINB9,CD36,BAP1,PMAIP1,FOXD3,IREB2,DXO,TCF21,LIG3,SRSF10,HAS3,MIR186,OTX2,JUNB,PRL,TRIM34,DMAP1,ENO1,AURKAIP1,LDLR,EEF1A1,NEUROD2,ZNF263,PPP4C,VEGFC,TRAF7,PELI1,PPARA,IFNGR1,RXRG,YWHAG,THRAP3,LDB2,RNASEL,FGR,GTF2F1,RFX5,ABHD6,ERP29,BTG1,ZNF267,GSKIP,NEK2,CD38,NDP,FKTN,ZBTB25,CAMK2N2,FXR2,GADD45A,HCLS1,DISC1,BMPR1B,TFCP2,PML,TERT,SNAI3,MIR491,CRADD,EIF2S1,PABPC1,CLU,OTULIN,MINAR1,MED30,MACROH2A2,RPS7,PKNOX1,NKX3-1,NFKBIL1,ADIPOR1,STK38,MAGEB10,PCBD1,NR2F6,CRTC2,SERPINB1,RAP1A,TFRC,ELOC,MIR100,MIR625,GTF2IRD1,BRMS1,TRIM3,CCDC3,NTRK3,ZNF319,CIPC,TLR8,MYT1L,MIR153-1,EIF4EBP3,EIF2B5,EIF3K,RFXANK,SOX3,DNAJB4,NFE2L2,MPV17L2,PRMT6,IVNS1ABP,SMARCB1,BMPR1A,TFE3,SEMA7A,DRAP1,UBASH3B,SRSF4,FAM162A,TNFSF12,EIF1B,SMARCA5,PIWIL3,ZNF740,SERPINH1,MIR148B,ZNF175,TCOF1,PHB2,COMMD6,POLR2G,SQSTM1,LEP,CD200,MCM3,DYNLL1,MIR34B,MED17,STK16,HOXB8,TRIM22,AIP,MTF1,CSTA,HSPE1,PYM1,PICALM,LITAF,IRF7,MIR200C,CCT2,SMAD1,ZBTB26,ZSCAN1,ACTN4,FOSL2,ORC5,HNRNPC,RNF126,DIRAS3,OAS1,TWIST2,IDH1,SETD3,COPS5,CDCA7L,SUMO1,TM4SF20,WASL,GCLC,DYRK1A,DDIT4,MIR152,ZNF177,ZBTB18,PROX1,CREBBP,TNFSF18,KRAS,PPP1R3C,IL1A,FGF10,IRF6,NCK1,TF,IRF9,ZNF397,RBM22,BRCA1,ALKBH5,SLC38A3,SERPINB6,BUD31,MIR31,SMAD2,MIR342,ZHX1,ZNF687,SNRNP70,IDE,APOBEC3F,UBE2I,MTM1,TNKS2,PSEN1,CD4,SOCS3,RBBP8,CAV1,IFNB1,MEPCE,MTG1,MEAF6,RBFOX2,TNKS,TAB1,AGAP2,RAB1A,PIM2,ODC1,CDKN2D,SUPT7L,APOBEC3D,PDCD5,SSBP1,CDK1,OSR2,RPS6KA4,EED,MED21,NFIL3,CHRM5,TNFSF8,CTDSP2,ITM2A,FITM2,CASK,MIR106B,HCRT,DLX1,PHF13,LRRC14,SSBP2,MIR126,MYC,ZER1,HSPB1,MARS1,MIR142,DAPK1,CDC20,PRKCA,BRD3,ACVR1,RAD23B,AZIN2,H1-6,EIF4E2,F2,POMT2,SLC35B4,PLSCR1,BCL7C,DCUN1D1,ZNF593,USP16,APOBEC3B,HSP90B1,RFC4,ZBTB45,TRA2B,BHLHA9,NFE2L1,ADNP,STRADB,CGAS,DAP,DFFA,BCL7B,HMGB1,SSBP4,LBX1,RGS2,VPS28,GTPBP1,GABPA,BCCIP,HNRNPH3,HRAS,PYCARD,CRLF3,POLDIP3,NAA15,RBBP7,DDRGK1,MAP3K11,IL10,FERD3L,STN1,SRSF2,ARMCX3,RAF1,MSX1,MIR145,ZSCAN5A,CX3CR1,TRAF1,TAGLN3,CDKN2C,NKX6-2,RFC5,PPP1R1B,COP1,MIR193A,GABARAPL2,HECTD1,FAXDC2,PGR,ZNHIT1,SLA2,PRKCQ,SESN2,MIR106A,EMX1,PPARG,DESI1,PAQR3,CCDC22,EPO,ZNF664,NR4A2,SERPINA3,MIR28,MNAT1,EGR1,IKBKB,IL34,EIF4H,NCSTN,NFYB,YTHDF2,CHRNA7,EZH2,UPF3B,IL3,PSENEN,MIR340,P2RY1,SRSF1,NKAP,FGF22,SIX5,ADORA1,ADORA3,MIR590,EYA3,DDIT3,DNAJC2,POLE3,CXCL8,CCNY,MIR133B,FKBP8,CTSC,LCMT1,SVBP,ITGA6,ATG101,UBE2D3,UBP1,MIR320A,EIF4A2,MET,TOLLIP,TSPAN5,KIT,ANP32B,FAS,MSH6,TGFBR2,UBE2D1,HNRNPAB,TSG101,E4F1,NR1H2,EGLN2,ZNF343,CDK5RAP3,MIR448,PPP3CA,FAM107A,SLC45A3,MIR182,ELAVL4,IL1B,ZNF787,AKT1,DYRK1B,EXOSC8,TLR6,MTERF2,RADX,SLCO3A1,IFNA13,MIR211,EIF4B,ENY2,CNOT2,WTAP,IGF1,APH1A,HMX2,DKC1,CALR,GRSF1,MIR675,TXN,GSTP1,MAX,TNFAIP3,GH1,RBBP4,TOX,CCND3,CREB3L4,MT3,MXI1,NEUROD6,INPP5E,MLLT6,PLCB1,TLR9,KCNIP3,ORMDL1,TNFRSF1B,MCL1,METTL18,RPL10,SMG8,E2F6,PPP2R5A,CDKN3,FABP4,DNAJC3,PPP1R10,LPCAT3,DNAJB2,IFNA2,CDC73,MEF2B,IKZF2,MAD2L2,SSBP3,NMI,FOXS1,ZBTB33,MIR204,CLEC6A,MIR423,ZNF576,ANXA4,CD80,GABPB1,UCN,GTF2A1,MED27,COPS2,PSMA6,AKT2,ERRFI1,MPV17,UHMK1,FOXN2,HMX1,SF3B4,CARHSP1,PRNP,MIR130B,DAPK3,SLX1A,NKX3-2,MIR223,G3BP2,ACVR1C,ERLIN2,KPNA1,DDX1,ELF1,IL6,MOB3B,EFCAB7,TOM1L1,USP38,MIR379,TRAF3IP2,BAX,SOX21,MMP9,CD86,PYDC2,GNAQ,IFNA10,PAIP1,GTDC1,MRPL13,CCNH,MRPL12,CYP1B1,TLR2,RPS13,AKAP8L,RNF10,FAM161A,HCAR1,STAT5A,VIP,VRTN,MAP2K6,NHERF1,WBP2,MAPKAPK5,ZNF805,NUP62,RDH10,MIR16-1,PIH1D1,DRD1,DCUN1D3,ZNF575,NR1I3,PSMC1,CH25H,TMBIM6,CD40,MED10,ACVR1B,INTS12,SGF29,HDAC6,MAGEB1,FOXA3,NME2,MED22,CCAR2,CREB3,STK11,NIF3L1,ATRAID,XPO1,TCEA1,TNRC6C,YES1,DUSP1,BIRC2,STAR,LACRT,EGLN3,NPC2,HR,CUL3,SETD4,NR0B1,NR2E1,PIK3R1,MAGED4B,FOXP2,PSMD1,NIBAN2,ISX,MIR218-1,TCP1,ELK4,TRUB1,CRYM,CCNB1,MIR137,IL15,FABP5,BCL9,MIR455,MIR298,SLC38A2,MIR874,CCAR1,CEP85,NF2,IL18,GTF2H2,WRAP53,UQCC2,BZW2,ELK3,EID1,INSIG2,FASLG,HNRNPA2B1,PIK3CG,SPOPL,IFT52,CBX7,NEO1,CACUL1,PDCD4,SERPINB11,ETV6,MAGOHB,CAMP,RGN,SUB1,IL1R2,STAT2,TMEM168,FIS1,DICER1,TOPORS,SF3B5,IGBP1,CNOT6,DLG1,IKZF5,TLR7,ZBED1,MIR29C,BUD23,RGMB,EDF1,IL5,KDM1A,MAP2K1,HDAC5,PRMT2,HGS,TOB2,STPG4,IGFBP4,ANKRD49,FCGR1A,MSL2,RABL3,SPP1,DHX9,ISG15,THAP7,HCFC2,ZNF345,ZNF501,BHLHE40,MIR346,OSBP,NEDD8,RLIM,TRIM8,TLE1,SPOP,SOCS5,HSPA5,BEND6,OPHN1,HTRA2,NPTN,TAF5L,SERPINB10,MYD88,IGFBP3,ZNF436,MIR149,TULP3,CD81,ARPP19,FASTKD5,FURIN,KANSL3,ZBTB17,MAVS,RPS9,H1-10,TOX4,ID1,YWHAH,TPD52L1,LILRB1,BARX2,CSF2,ETFBKMT,RFX4,STOX2,IL6ST,GTF2F2,SRSF12,EFNA3,ZNF322,ZNF821,PELP1,EPHA4,MOSPD1,RTRAF,MAGEH1,IGF1R,SFRP1,RCHY1,RBM12,TIMP3,FERMT2,CSNK1E,LRRTM3,PPIA,CDC42,MIR17,RBM38,CEBPG,PAIP2B,FOXC2,CTSD,NEUROG2,NFYA,RIOX2,SDR16C5,TMSB4X,CDK9,NDN,RBM5,DRGX,NAB1,PHF12,CITED1,RB1,RNF141,TYMS,SSU72,HMG20A,ORMDL3,TOP2B,BCKDK,BCL6,SH3BGRL,HFE,CTDSPL2,PFDN5,HINFP,ABHD5,OAZ2,FBP1,ELAVL2,TBC1D24,MED11,PSMD3,IL1RAP,ZNF511,TNF,SHMT1,FGF3,HMGA1,ACTB,XCL1,NAB2,SF3B1,RBPJ,BRMS1L,ATP1A1,MIR191,CDK8,AVPR1B,EDA2R,RUVBL1,PDE12,IMPACT,PLGRKT,NQO1,SUFU,RHOG,SUV39H1,MLF2,MIR503,MLF1,MIR212,APOBEC3H,SGTA,EPCAM,ZNF668,LUM,HMCES,C1QTNF1,HINT1,RNF139,APOC2,TRIM44,RBCK1,IFRD2,PSMB9,RPS26,TCEA2,GTF2I,EIF2B2,LHX2,PRIM2,UGT1A1,MGMT,PCGF2,CRABP2,TRIP4,ZNF574,SAP18,MIR26B,ITGAV,CNOT8,RAP2C,GHR,TGIF2LX,KLF4,ZBED3,APLNR,TLR4,ARF4,TNFSF10,ACTL6B,MAEL,STK4,CIAO1,SOST,EPOP,MCM4,PCGF6,OAZ1,ASCC1,LEPR,SOD2,NEK7,ZNF362,SNX12,ODAM,AATF,MIR206,MLLT11,SKP1,PLAA,CTDSP1,PHF21A,ARRDC3,CDK12,MSN,CRKL,DIRAS2,TRIM24,MAF1,BCL2L1,TSPAN15,TIRAP,PKIB,PPP1R8,GSK3A,KPNA6,DEDD,BAD,DERL1,GMNN,CDC7,UBE2V2,ZMYND11,ZNF862,AKAP17A,GABARAP,PRMT5,TANK,SELENOS,KHDC1,RFC3,EP300,OVOL1,BOK,PIK3R3,WDR77,BACH1,CTSK,CRTAP,GPX1,LSM14B,CCNI,RTN4,POGK,ILDR1,ZNF280B,FMC1,RGCC,TIA1,MYBL2,MSX2,LILRA2,RBFOX3,MIR519D,MTG2,MIR30B,SIN3A,ELK1,LYAR,BCL2A1,EIF4E3,MIR210,POLR3F,RMI2,RMND1,ZNF592,POU5F1,JUN,MORC2,ROPN1B,MIR885,CBX3,HSPD1,GNMT,MTA3,EMX2,SERPINA5,CXXC1,ZFP1,FLOT1,FOXP1,UBE3A,IL12B,RNF14,MIR185,PCBP4,SERPINA1,USP2,COPS7A,CAMLG,UBB,BGLAP,MIR107,ZFP64,MIR181D,HP1BP3,CCNF,POU3F4,TRAF6,CCL19,HOXD12,PLAGL1,RNF40,TRIB1,MIR378A,FOS,CHI3L1,PSPC1,PRSS37,IRF2BPL,HINT2,HNRNPF,FAM168A,RPAP2,NFKB1,WBP1L,ZKSCAN1,LRIF1,TESK1,HLF,SUPT3H,P3H1,SETD5,MIR205,KLF10,PCGF3,RALB,ZNF32,ELP3,ATF3,SCML2,SLC7A11,ELF5,CSRNP1,DUSP22,MIR24-1,SMAD3,KMT5B,EIF4A3,HNRNPD,WNT2,RHBDD3,TAF9,IRF2BP1,TRIM62,TMIGD3,UTP15,AFAP1L2,INSM2,PQBP1,IRF1,ITM2B,STARD4,TFIP11,NTRK2,CCT5,LMO3,IFI16,TCEAL7,NBN,METTL14,ACTR2,CTNNBIP1,RGP1,TICAM1,SMAD9,MIRLET7I,MECP2,MIR181C,BMPR2,EXOSC3,CELF6,TAL2,MIR29A,NRDE2,MTMR2,PTGES3,SUMO2,PPID,ZNF609,ANGPT1,CDK20,SRC,HEXIM1,ZNF22,HNRNPK,TRIM21,NOVA1,ATF4,ZBTB5,DTL,STX5,GPR37,TENT2,BIRC5,TAB2,IFNG,PRKRA,OAZ3,MEF2A,MIR135B,TACR3,HBP1,CCL21,MIR20A,NFE2,TADA3,CIRBP,BAZ1B,CSTB,CDK7,MAFG,USP14,MAD2L1,MMD,PFDN2,ATP2B4,MACROH2A1,RIT2,MIR708,CTBP1,PRKCB,SHC1,ZC3H14,ZNF174,PAGR1,ZNF250,PTPN22,SOX2,PDE8A,NFKBIB,TRIM37,RAP2B,IRF2,USP13,HSBP1,FMO1,ABHD14B,PXYLP1,CCNQ,SNX33,TPPP,CDH13,PIWIL2,GREM1,MTDH,ADTRP,HNRNPH2,SLC6A3,NOTCH2,RBM7,SVIP,SRPK2,RASL11A,DBNDD1,METAP1,PAK6,MIR144,CHP1,TGFB2,SEC22B,RING1,PCNA,MXD1,SPRED2,ZBTB38,ZMYM2,RUNX1,CNKSR3,ZMPSTE24,GFI1,MIR208A,PKIG,COPS4,SNX3,TAF2,WWP1,IFT57,S100A11,ZGLP1,ARL6IP5,EGR2,PPP1R2,LILRB4,ARB2A,RPS27L,HBEGF,TRIM26,AP2A1,ZBTB42,PFDN6,TRIM11,SP4,USP8,RC3H2,SMG5,HTR1A,HSP90AB1,CBFB,CD28,TAX1BP1,VGLL4,ERLIN1,FKBP1B,MSTN,CAV3,ZCCHC17,BEND5,MEF2C,PSRC1,MIR190B,APLN,MOV10,KLF9,SAP30BP,HTR2A,INPP5K,GATAD1,HSP90AA1,TGIF2,SMAD5,SOCS4,MAGED2,CDK5R1,SPON1,DNAJC30,DNAJC19,FMO2,WWP2,HNRNPA1,GLO1,IER3,CREB1,PRDX3,APOBEC3G,MTRES1,TFDP2,LDB1,PSME1,MIRLET7C,CGGBP1,RHOH,ACOT8,PSMD14,PSMD10,TNFRSF14,CXCL10,CIDEB,SPHK2,SPINDOC,H2AX,FBXW11,OGG1,MIR424,CXXC5,MIR495,CORO1C,YTHDF1,INO80C,ZNF770,CAB39,S100A10,LARP4B,BATF,AGER,MIR361,ZNF304,MIR23A,ADIPOQ,FGF17,LBH,H2AZ1,YAF2,ROCK2,CBX5,TRAF2,RPS3,EEF2,TRIM6,FOXP4,H1-1,ETF1,DCP2,RAP2A,RNF20,TSPO,ZBTB6,BTG2,JUP,GPNMB,MIR711,RNF187,MIDEAS,CYP7A1,SP1,SFRP4,RPL23,CSNK1A1,CCNA2,CLN8,RAD21,POLR2L,CNOT7,GAPDH,TGFB1I1,MYRF,FBXO22,FZD6,ESR2,IER2,CHRNB2,IL7,RFXAP,EZH1,HELT,PTPRQ,ATXN1L,FGFR1,VGLL2,PIWIL4,ACSS2,HUWE1,PTPN11,ENC1,CKS1B,OPA3,TRIM27,CDK6,NONO,TFPT,FOXI3,TAF7,DIPK2A,PFDN1,TENT5D,SPPL3,CLEC7A,IL21,ZNF451,VPS72,MITF,IL13,ZNF671,FHIT,MIR34A,PFDN4,RPL13A,MED13L,XBP1,PID1,CYTL1,PAK2,MIR130A,TRIM63,IL2,MIRLET7B,CAAP1,CCND1,HIRA,TSC22D3,PAIP2,CNR1,SOD1,AR,PHC1,TAF11,NRP1,PCSK9,GNB3,FGF1,MIR125A,PRKCE,PSMA3,SMU1,MIR10B,DIO2,PARL,ATF1,RGMA,WNT7A,CEBPE,SIAH2,TGFB3,AIFM1,FUBP3,DUSP26,ACO1,RPS4X,SERTAD2,ITGA2,RPL26,CCT7,BRD9,SPRED1,SAP30,NFKBIA,CLK4,SIRT7,TCF23,BAK1,VDR,ZNF688,MIR345,MIR877,TEF,HDAC3,IFNK,ATG7,SMARCD3,ZNF24,MIR148A,ZBTB16,AQP11,EHD4,LCP2,DNAJB6,SFN,NACC2,MIR96,UBE2S,TNIK,ZNF507,RIGI,PAX6,SMYD3,WNT10B,TXNIP,BABAM1,PRKAG1,TP53INP2,PPP2CB,PPP1R12A,ACTL6A,FOXP3,CD274,CLIP3,E2F4,HAX1,SPRY1,SNTA1,KLHL25,SMARCE1,TENT4A,ZNF513,MAGEC2,MMP14,MCM6,UBE2K,AHCYL1,ID4,TP53INP1,ZNF581,ZBTB2,EIF4E,BAHD1,PTP4A3,C1D,APOBEC3A,ZNF287,TACO1,RARRES2,G6PD,MYLIP,MIR373,PIAS1,DIRAS1,CDK4,ZBTB39,TBK1,XRCC5,DUSP6,PSMC5,SEMG2,PHF23,CHCHD2,NPPC,IGF2BP1,PDE2A,CIART,EIF5B,ARL2BP,JMJD8,RBM42,DNAJC1,POU1F1,SERTAD3,NLRP1,SYK,FGF16,PITHD1,BOLL,HNRNPL,EAF2,PRR5L,NOG,TESC,S100A8,EWSR1,PRDX6,FBXW7,MALSU1,TRIM5,SELENOT,APOBEC3C,APBB3,VSIR,DCUN1D5,MIR101-1,CERS2,MED9,MAGEA4,ZSCAN25,TRIM32,TRMT112,UBE2L3,CNOT6L,PSMC4,RASD1,MED23,LAMP3,SERTAD1,KLF1,PIK3R2,PRKACB,OSM,YWHAZ,BSCL2,FZD4,KRBOX4,CAPN2,SOX14,DEK,CAMK1,BEX3,NSMCE3,NUDT16,MTPN,PRELID1,EIF3E,FGF23,VEGFA,CLK1,IL23A,MTA2,CTSA,SATB1,ZNF704,TIMP1,RB1CC1,CSH1,KLF3,CCDC85B,H1-3,SERPINI1,ASB11,RNF41,CD40LG,TFEB,MIR140,THY1,MIR939,TAF10,IL17F,PIK3CA,TAF1D,APEX1,TCIM,NTF4,ZC4H2,SUPT4H1,ROCK1,PHAX,MIR15A,CPEB1,CSNK2A1,HNRNPA0,HOXC4,DHRS7B,PAEP,AZIN1,SOX9,NDFIP1,CBL,ZNF7,SNAI2,DCAF5,DLG3,RBM23,FKBP1A,EIF4EBP2,NR1I2,PRPF19,TRIM29,PELO,ING5,CDC5L,MIR339,IRF8,SAP30L,NUCKS1,CHRAC1,RFC2,HOXB1,GLRX2,RAB1B,DKK1,SPOCK1,RNF8,STAT6,CCR7,SRSF7,LCORL,ADRB2,PRDM4,HAND2,MBD3,C9orf72,PARM1,DPEP1,KLHL15,MIR192,DUSP3,MAP2K3,ZFAND2A,RERE,PAOX,OTUD7B,RPRD1B,MIR9-1,SCAND1,ZNF596,THAP1,MDC1,IL4,ILF2,MIR146A,DGCR8,NKRF,SCML1,GPBP1L1,TADA1,SPIN3,SWAP70,ING2,EFNA5,DKK3,RUVBL2,USP5,LANCL2,MIF,HNF1B,EIF5A2,RWDD3,MIR132,BCL10,IL12A,HEY2,IRF3,MAP3K12,STK3,PARD6A,KLF12,ZNF518B,SETD7,RNF34,CCL5,DMTF1,RORB,CST3,RPS14,TRIM68,TLR3,DYRK2,ZNF652,FLCN,SECISBP2L,NUPR1,AGO1,CRYAB,DUSP19,FZR1,YWHAB,MIR214,ZHX3,PPM1D,ZBED4,NLRP3,H1-5,IRF4,CASC3,CLDN3,LSM14A,MED4,SUPT5H,TENT5C,CDKN1A,MDFI,TAFAZZIN,ZNF655,RPL6,EID2,ILK,NLRP2,ZNF365,TNFAIP1,DNAJC10,STUB1,FGF7,HEXIM2,CDK5,PLAC8,CLDN4,MIR98,KDM2A,GTF2A2,DUSP10,PKIA,CCT8,CAMK2N1,MUL1,CX3CL1,NGRN,RPA2,PHB1,ING1,MID1IP1,CDKN1B,TRIM52,TRA2A,FOXJ3,RBM3,RBM15B,UFL1,PSME2,KPNA2,LGALS3,DET1,ZNF692,ZBTB14,TRIM15,CYP27B1,ZNF189,ZNF326,MIR195,ZNF526,FAF1,PIWIL1,DROSHA,HEXB,TIMP4,ZNF473,ZNHIT3,CSRNP3,PPIB,HSPA8,PTPN1,INTS10,BAG2,MIR147A,PAX9,IFI6,DLG4,JADE1,ZNF790,MDM2,SDCBP,TP53,MIR1-1,DDX5,NCBP2 |
| 3.220e-04 | -8.04 | ATP5F1D (ATP synthase F1 subunit delta) | protein interactions | 513 | 127 | 54 | 19454 | 5460 |
CCDC90B,ACKR3,VDAC2,ESR2,CPT2,ATP5F1B,TUFM,ATP5F1A,PMPCA,AUH,MYC,MTG2,RIT1,ATP5MC3,GFM1,ATP5F1E,CERS2,DHRS4,TOMM22,MTRES1,CAV2,UBE2M,ATP5PO,GATD3,COX4I1,SSBP1,RMND1,ATP5PD,PRNP,FZR1,ATP5MG,COX5A,MDFI,GRSF1,TMEM70,HINT2,ARB2A,ATP5PF,NDUFB5,IMMP2L,FASTKD5,MEPCE,TRIM63,VDAC1,KRAS,METTL15,MRPL11,E2F4,ATP5PB,FURIN,GFM2,EXOSC3,SKA3,EZH2 |
| 3.220e-04 | -8.04 | ARMCX3 (armadillo repeat containing X-linked 3) | protein interactions | 51566 | 127 | 54 | 19454 | 5460 |
SLC25A46,NDUFV2,CSNK2A1,TSEN34,RHOG,POR,ESYT1,ANKRD50,EEF1B2,ARL10,ATP6V1A,RAC2,NDUFS8,LMAN1,UQCRH,MTCH2,RANBP1,RPAP2,TUBA1A,CLEC2B,RPL15,EZH2,NDUFS3,JCHAIN,HMOX2,DCAF4,FIS1,ATP1A1,THTPA,ZMPSTE24,MAF1,FAM177A1,OPTN,UQCRC2,GANAB,RMDN3,PTEN,ATP5F1B,RANBP6,ESR2,TOMM22,EHHADH,UQCRC1,PRDX3,SEC62,HAUS2,CYC1,PML,AKAP1,MEA1,HSCB,EMC1,PDHB,TOMM20 |
| 3.230e-04 | -8.04 | GTPase complex | cellular component | GO:1905360 | 39 | 22 | 19108 | 5553 |
GNG3,GNG7,GNG5,GNAO1,GNA11,GNB4,RRAGA,GNAQ,GNGT2,HRAS,GNG11,RRAGB,GNB3,GNB1,GNG2,GNG13,GNG12,GNAZ,GNAI3,GNG10,GNAI2,GNA14 |
| 3.241e-04 | -8.03 | kinase regulator activity | molecular function | GO:0019207 | 272 | 108 | 18094 | 5411 |
CDKN2D,GSTP1,CXCL10,RHOH,FAF1,TRIB1,TOPBP1,CKS2,NCK1,GREM1,RAC2,STK4,BCL10,PIK3R1,MOB3B,GHRL,TAB1,PPP1R1B,CCNA2,CKS1B,HEXIM2,STK3,NBN,ALKAL1,CCL5,CAB39,AKT1,ELP3,TGFBR2,CDK5R1,YWHAB,CDK4,PKIB,MAP2K1,RHEB,PRKAG1,TOM1L1,CDKN1A,PIK3R2,SH3BP5L,STK11,CHP1,MAP3K12,CNPPD1,AGAP2,RGCC,GSKIP,PRKRA,HSPB1,IL2,ADIPOQ,LAMTOR3,SOCS3,STRADB,TESC,STAP1,CCND1,CD40LG,LRP6,CCNQ,SOCS5,PKIG,AFAP1L2,HTR2A,CAV1,CISH,CCNH,PDE8A,SLA2,MOB3C,CAMK2N2,HYAL2,CDKN2C,CAMK2N1,YWHAG,SPRED1,SFN,CCNF,NEK9,PAK2,DUSP19,DNAJC3,CCNI,MNAT1,VEGFA,SOCS2,DELE1,CCNB1,PIK3R3,CCNY,MACROH2A1,EPO,CSNK2B,SOCS4,LILRB4,HEXIM1,CCND3,RPLP1,IL6ST,MT3,PKIA,PIK3CA,HBEGF,CDKN1B,SPRED2,EFNA5,BCCIP,HSP90AB1 |
| 3.254e-04 | -8.03 | Mitochondrial translation initiation | REACTOME pathways | R-HSA-5368286 | 87 | 43 | 10285 | 3229 |
MRPS26,MRPL23,MRPL49,MRPS23,MRPS33,MRPL20,MRPS28,MRPL50,MRPL41,MRPL33,MRPS18B,MRPL47,MRPL11,MRPL53,MRPS18A,MRPL57,MRPL13,MRPL16,MRPL9,MRPS18C,AURKAIP1,MRPL22,CHCHD1,MRPS35,MRPS34,MRPL51,MRPS25,MRPS16,MRPS11,MRPS7,MRPL34,MRPL10,MRPS17,MRPL36,MRPL52,MRPS9,MRPL40,MRPS21,MRPL24,MRPL17,MRPL12,KGD4,MRPL18 |
| 3.268e-04 | -8.03 | HOXB6 (homeobox B6) | protein interactions | 3216 | 58 | 29 | 19454 | 5460 |
TMED7,AHCYL1,SAT1,EP300,PLSCR1,GLUL,TRAPPC4,TRAPPC14,PKNOX1,NTAQ1,CREBBP,OST4,GGPS1,TCF21,TRAPPC6B,KBTBD6,PRRC2A,SRPK2,TCEAL1,HNRNPL,KCTD9,GPX1,KCTD10,LRRC1,TRAF7,CSNK2B,TRAPPC3,TRAPPC10,GYS1 |
| 3.268e-04 | -8.03 | PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1) | protein interactions | 162466 | 58 | 29 | 19454 | 5460 |
HSPE1,PTGES3,PEBP1,HSPD1,HINT1,PRDX6,PDIA6,PGK1,RPN1,RANBP1,CCT5,PGRMC1,NECAP2,DDX39A,TCP1,LDHA,CCT7,PDCD5,UBE2N,GANAB,FKBP4,CCT2,CKB,NME2,RASSF8,OAT,PGAM1,PDIA3,PPIB |
| 3.268e-04 | -8.03 | PPWD1 (peptidylprolyl isomerase domain and WD repeat containing 1) | protein interactions | 23398 | 58 | 29 | 19454 | 5460 |
SEC13,GTF2E1,PPIB,PSMD1,AR,SNRPB,RIT1,ACOX1,CCNF,METAP2,EED,TOP1,SNRNP40,CDC5L,SF3A1,TP53,RPA2,ZMYM6,CBX3,NUPR1,RPA3,SNRPA,PML,NUP50,PPIH,SRSF7,KRAS,CHRNA7,SSRP1 |
| 3.268e-04 | -8.03 | RETREG1 (reticulophagy regulator 1) | protein interactions | 54463 | 58 | 29 | 19454 | 5460 |
LMAN1,TMPO,DNAJC1,SEC61B,MAP1LC3A,HSD17B11,PTPN1,ESYT1,RHOG,RAB5C,RAB11A,FKBP8,GABARAP,RETREG1,RAB5A,DERL1,RAB9A,TMT1A,SSR1,STIM1,RPN1,GABARAPL2,ST7,GABARAPL1,DNAJC25,MAP1LC3B,OTULINL,SNAPIN,SEC62 |
| 3.280e-04 | -8.02 | UBC_1 | prosite domains | PS00183 | 26 | 16 | 12186 | 3388 |
UBE2G2,UBE2N,UBE2F,UBE2K,UBE2E2,UBE2M,UBE2H,UBE2D1,UBE2B,UBE2S,UBE2L3,KRAS,UBE2I,UBE2E3,UBE2A,UBE2D3 |
| 3.298e-04 | -8.02 | UBIAD1 (UbiA prenyltransferase domain containing 1) | protein interactions | 29914 | 110 | 48 | 19454 | 5460 |
ARF6,FNDC9,STX6,LMAN1,CRB3,HRAS,RAB35,HSD17B11,ADD1,GJA1,RHOG,STYK1,LAMP2,RAB5C,LAMP3,KRAS,SLC7A14,RAB3B,SLC6A8,TMT1A,NTRK2,RPN1,RAB4A,TMEM14B,MGST3,REEP4,LMBR1L,VEGFA,CCNF,ELOVL4,CYB5R3,RETREG3,LAMTOR1,RHOB,FCER1G,RAB2A,RAB11A,SCN3B,GORASP2,STX7,PXMP2,RAB9A,RAB5A,SSR1,TIMMDC1,BET1,SEC62,ST7 |
| 3.298e-04 | -8.02 | ZNF22 (zinc finger protein 22) | protein interactions | 7570 | 110 | 48 | 19454 | 5460 |
CFTR,RPLP0,RPL26L1,MACROH2A2,MRPS18A,HSPA8,RNF113A,NOG,MRPL20,NPM3,DGCR8,NUCKS1,RPL4,RPL26,MYC,RPL7A,H1-1,RPL37A,PRKRA,FGFBP1,ESR2,RPL19,RPL13A,H2AX,H1-3,ILF2,RPL18,RPL3,PPAN,RPL28,SRSF4,RPL17,SSRP1,MRPL9,TRA2A,DDRGK1,RPS2,SNRNP70,PRR3,SRP14,SRSF1,KRR1,SURF6,ZBTB2,RPS10,RPS16,LYAR,RPL7 |
| 3.300e-04 | -8.02 | oxidoreductase activity, acting on a sulfur group of donors | molecular function | GO:0016667 | 55 | 29 | 18094 | 5411 |
TMX4,SRXN1,CCS,PDIA3,TXNDC12,GSTO2,DNAJC10,TXNRD2,TMX3,TXNDC17,PDIA6,PDIA2,PRDX3,MSRB3,GLRX,TXNL1,TXN,PGK1,SESN2,TXNRD3,TXNRD1,TMX2,ERO1A,PCYOX1L,GLRX2,MSRB1,GSTO1,SELENOT,CHCHD4 |
| 3.306e-04 | -8.01 | LHX9 (LIM homeobox 9) | protein interactions | 56956 | 17 | 12 | 19454 | 5460 |
LDB2,SMURF1,RIGI,PARP2,ZHX1,LMNA,SMAD2,SSBP3,LDB1,SSBP4,CSNK2A1,SOX2 |
| 3.308e-04 | -8.01 | CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10) | protein interactions | 400916 | 74 | 35 | 19454 | 5460 |
COX6C,ATP5PO,NDUFS3,GHITM,NDUFA5,EFHD1,ATP5PB,MTCH2,GLRX5,CFTR,CHCHD2,THRAP3,CMAS,POLDIP2,FAF1,RBM23,ATP5MK,SFXN1,SLC16A1,CLPB,RBM27,CHCHD4,CHTOP,LSM14B,SLC25A1,CLPX,STOML2,COX5A,STARD7,MRPL23,RNASEH1,ATP5PD,ZNF593,PRRC2A,CYB5R3 |
| 3.308e-04 | -8.01 | NDUFB1 (NADH:ubiquinone oxidoreductase subunit B1) | protein interactions | 4707 | 74 | 35 | 19454 | 5460 |
PPP2R1A,MTCH2,ALPL,NDUFA5,GPR34,MED23,NDUFS3,NDUFS6,PGK1,EWSR1,NDUFC2,NDUFB5,NDUFA4,SDHC,PSMD12,MRPL22,HSCB,DNAJC30,NDUFV2,ATP5F1A,NDUFB10,NDUFB7,RPL23,TAFAZZIN,SKIC8,NDUFA1,CYB5A,COX4I1,NDUFB4,DLST,CSTF3,ATP5PD,NDUFAF4,PSMD4,KCTD10 |
| 3.311e-04 | -8.01 | TBC1D12 (TBC1 domain family member 12) | protein interactions | 23232 | 11 | 9 | 19454 | 5460 |
STX7,RAB4A,XPO1,LAMP3,RAB9A,CSK,LAMP2,ATG9A,RAB11A |
| 3.311e-04 | -8.01 | IL15RA (interleukin 15 receptor subunit alpha) | protein interactions | 3601 | 11 | 9 | 19454 | 5460 |
POLR2F,TRAF2,CDK4,IL2RB,IL2RG,CASK,RCVRN,BCL10,IL15 |
| 3.311e-04 | -8.01 | SPBC36B7.05c (putative ubiquitin-protein ligase E/phosphatidylinositol(3)-phosphate binding protein) | protein interactions | 2540987 | 11 | 9 | 19454 | 5460 |
UBE2E3,UBE2B,UBE2D1,UBE2D3,UBE2V2,UBE2N,UBE2E2,UBE2W,UBE2V1 |
| 3.312e-04 | -8.01 | HSPBP1 (HSPA (Hsp70) binding protein 1) | protein interactions | 23640 | 162 | 66 | 19454 | 5460 |
NT5C2,DDRGK1,MAPK4,MED4,DNAJC7,ARMC8,TUBG1,BRD9,CBFB,FBXO32,ARMC1,EGLN3,G6PD,FZR1,HNRNPL,PRNP,UBXN2B,ESS2,MAP1LC3B,MAP2K3,ELF1,KBTBD4,PPME1,SH3GLB1,HGS,METTL21A,ACTR2,MKLN1,ERO1A,FKBP8,GMNN,DRAP1,CUL3,ZBTB38,UBE2H,QSER1,CFAP298,PTEN,CCNF,STUB1,LMBR1L,METAP2,SURF2,LRIF1,TOM1L1,DUSP10,TAB1,EDEM3,HEXIM1,FKBP10,OXSR1,PIH1D1,RPA2,P3H1,METTL14,HSPA8,HMCES,CLK1,NUP50,ARFIP1,TTC1,MAVS,RPA3,FLYWCH2,HSPA5,GON7 |
| 3.312e-04 | -8.01 | KRT14 (keratin 14) | protein interactions | 3861 | 162 | 66 | 19454 | 5460 |
PIAS1,HSPA5,UFL1,PIK3R2,OIP5,INPPL1,DDX39B,HEXIM1,WTAP,PIH1D1,SDCBP,METTL14,CFTR,VIRMA,AP2M1,UBASH3B,ALB,PTEN,ARF1,EIF4A3,RNF208,UBE2H,SPOP,TRIM23,RC3H2,BTF3,SMARCE1,MYC,HNRNPC,CUL2,CUL3,MEPCE,UBE2A,ENKD1,TRIM26,ARL5B,NEDD8,TRIM37,FAF1,CTTNBP2,HGS,RNF8,TFCP2,EZH2,NEFL,FBP1,TP53,MDM2,FZR1,INA,CAND1,KRT8,ARL4D,EFNA3,ARL10,POU5F1,CBL,MAGOH,SHC1,COPS5,HNRNPA1,HDAC6,DDRGK1,GAS8,DPP4,EMC4 |
| 3.315e-04 | -8.01 | human chr7p15.3 | chromosome location | human chr7p15.3 | 31 | 16 | 26134 | 5823 |
GPNMB,NUP42,NPVF,HYCC1,IL6,TRA2A,PALS2,KLHL7,TOMM7,FAM221A,NPY,MALSU1,SP4,CDCA7L,RAPGEF5,CCDC126 |
| 3.316e-04 | -8.01 | SARNP (SAP domain containing ribonucleoprotein) | protein interactions | 84324 | 130 | 55 | 19454 | 5460 |
DDAH2,NMI,DAPK1,UBE2I,CSNK2B,EIF4A3,ZNF330,PPIG,CHTOP,FYTTD1,CHORDC1,SUB1,MYC,STX7,YTHDF1,PFKFB2,HTR1A,CSTB,BAP1,THOC3,DDX39B,ADSS2,CDK7,ZC3H14,ATG16L1,MPP1,THOC1,THY1,ALYREF,PRCC,THOC2,DRG1,MAGOH,BRD3,PPM1B,SKIC8,POLDIP3,SRPRB,H3C1,RTCB,ZC3H11A,CDK5,TRIM21,EWSR1,SEPTIN7,HSPD1,SCYL2,NUPR1,SH3GLB1,PDHA1,EXOSC8,DDX39A,MAP1LC3B,E2F4,UBL4A |
| 3.321e-04 | -8.01 | UBR4 (ubiquitin protein ligase E3 component n-recognin 4) | protein interactions | 23352 | 298 | 111 | 19454 | 5460 |
TPGS2,COPS5,DPP4,MOV10,EPHB6,PRNP,TES,RB1,RAP1B,COX4I1,FURIN,RNF181,UBE2B,TFRC,HSPA13,WBP11,APOO,AURKAIP1,TP53,KBTBD4,RIGI,ABHD10,DUSP19,STX11,SEM1,H3C1,ADRA1A,MAP1B,FAF1,SLX1A,UBE2H,UHMK1,NRP1,TXNIP,EMILIN1,PSMB2,SRPK2,VIRMA,UBE2L3,CTSB,PPM1M,PSMC5,MOB4,CCNF,MET,RPA2,METTL2A,CFTR,CRYL1,STK38,FBXW7,EIF5B,KDM1A,EGFL7,SIRT7,BAP1,DDX46,RPA3,LY6G5C,POU5F1,AGR2,NCK1,NT5C2,DDRGK1,INSYN1,CFC1,PRPF19,EGLN3,SUMO2,KRT8,SIN3A,MOB3C,SART3,TUBB4B,EZH2,FAF2,SOX2,SUPT5H,TOP3B,IMMP2L,SRSF4,UBE2A,GNL1,KRAS,HSPD1,SERPINH1,RIT1,PSMD14,BRCA1,PSKH1,SRGN,PRMT6,CUL3,MYC,ESR2,STAT2,PHF21A,GTF2F1,LMBR1L,PIH1D1,CDKN1A,ELFN2,PGRMC1,BET1,STAU1,HADHA,RAB5A,AKAP1,BIRC2,HSPA8,TIMP3 |
| 3.325e-04 | -8.01 | exocytic vesicle | cellular component | GO:0070382 | 241 | 95 | 19108 | 5553 |
BORCS5,STX11,RAB3D,ATP6V1D,RAB6A,PDE4B,SLC35G2,ATP6V1G2,MME,RAB5A,DNAJC5,RAB11B,STX10,MTMR2,CPLX3,NCSTN,SLC18B1,MT3,STX6,SLC4A8,GRIA1,SLC32A1,IGF1,PSEN1,SYP,BCL2L1,STX7,PICALM,SYNDIG1,LAMP5,SYNGR3,TMED9,SYT4,ATP6V1C1,OPRK1,ZNRF1,RABAC1,VAMP1,RAB8B,SEMA4C,VTI1B,SYN3,RAB5C,ATP6AP2,SYT2,RAB13,IQSEC1,RAB3C,GABRA2,COPS5,SNAPIN,ROGDI,STX1A,SEPTIN6,SNAP91,VAMP2,SYNGR4,SYPL1,PSEN2,CTTNBP2,ATP8A1,PPFIA2,COPS4,STX12,HSPA8,SCAMP5,DLG4,APH1A,SYNGR2,RAB3A,GAD2,BACE1,SV2B,LGI3,SNAP25,ICA1,TRAPPC4,SYNGR1,RAB3B,ATP6V1G1,DISC1,SLC35F1,SLC17A5,PRRT1,SYNPR,PPT1,PICK1,ATP6V1A,NTF4,SVOP,STX16,RAB40AL,HCRT,RAB27A,GABBR1 |
| 3.335e-04 | -8.01 | NDUFB7 (NADH:ubiquinone oxidoreductase subunit B7) | protein interactions | 4713 | 96 | 43 | 19454 | 5460 |
NDUFB6,NDUFB10,LMO2,CDKN2D,ZMPSTE24,ATP1B3,CHCHD4,UQCRC2,CINP,NFKBIB,METAP2,ZNF330,SCNM1,UQCRQ,MAGOHB,LAMTOR3,CHIC2,CAPN1,MPV17,NDUFC2,PHB2,NDUFV2,ATG9A,RAB5C,NDUFB8,NDUFA1,SPRED2,COX4I1,GYS1,NDUFS8,SLC25A12,TOMM7,ATP5PB,NDUFA2,NDUFA12,CRELD1,NDUFS6,NDUFS3,NDUFB5,NDUFA4,CDCA7L,ENKD1,DNAJC30 |
| 3.335e-04 | -8.01 | PRIM2 (DNA primase subunit 2) | protein interactions | 5558 | 96 | 43 | 19454 | 5460 |
STN1,DCAF11,CIAO1,MOV10,MYC,BTF3L4,SUV39H1,BTF3,ATG7,TOP1,RPL35,SNRNP40,GFOD1,MAD2L1,POLE3,TNFRSF1B,ZNHIT6,FBXO32,POLR3H,PNMA2,RPA2,CDK8,TPT1,PSMC4,ATG16L1,KIF2A,RFXANK,CDK20,SLC31A1,HSCB,KDM1A,TRA2B,KRAS,SSRP1,MRPS18C,POLA2,POLD2,RPA3,PRIM2,SNAPC1,DUSP9,S100B,PCNA |
| 3.344e-04 | -8.00 | negative regulation of DNA-binding transcription factor activity | biological process | GO:0043433 | 155 | 66 | 18204 | 5365 |
SFRP4,TCEAL7,CCDC22,TRIB1,CTNNBIP1,MIR21,UFL1,SUFU,CYP1B1,CEBPG,NLRP3,BRMS1,GFI1,NR0B1,RB1,DAP,SUMO1,PRMT2,TAX1BP1,ANXA4,MIR16-1,FAF1,CDK5RAP3,FZD6,FOXS1,KDM1A,MDFI,RBCK1,PSMD10,MAD2L2,DDIT3,COMMD6,BHLHE40,PROX1,PYCARD,TRIM21,MIR140,CD200,PRNP,PHB2,NFKBIL1,KLF4,OTULIN,RWDD3,FOXP3,ADORA3,PPP2CB,ID1,TRIM37,MIR9-1,MIR15A,NUPR1,PYDC2,TMIGD3,MIR1-1,TNFAIP3,MIR144,LRRC14,XCL1,WWP2,IL10,MIR101-1,CHP1,G3BP2,MIR133B,NFKBIA |
| 3.352e-04 | -8.00 | PAK4 (p21 (RAC1) activated kinase 4) | protein interactions | 10298 | 165 | 67 | 19454 | 5460 |
YWHAG,XPO1,LAMP3,YWHAH,FEM1B,YWHAB,RHOG,PPM1B,DLGAP4,GJA1,RAC2,CDK6,RAB35,STX6,DIRAS3,LMAN1,MDM2,CAV1,G6PD,CDC5L,ARF6,KCTD3,THOC1,SUPT5H,GCLC,TP53,ITGB5,PNMA2,NEK9,FBXO25,PAK6,FLOT1,G3BP1,KRAS,PTPN4,DNAJC5,RAB2A,SUB1,CUL2,CIAO1,SFN,PMPCA,H1-1,LAMTOR1,YWHAZ,WDR20,RHOB,RAN,DLST,CCDC90B,SRPK2,RHOJ,ACTB,CDC42,TRIM36,PAK5,PAK2,RPA2,PPARG,SQSTM1,RAB9A,RHOU,RPA3,ITGAV,STX7,DGCR6L,STAU1 |
| 3.359e-04 | -8.00 | NUP93 (nucleoporin 93) | protein interactions | 9688 | 249 | 95 | 19454 | 5460 |
VIRMA,MGST3,UBE2I,CCNF,UBE2H,MAPRE1,XPOT,BICD2,MTPN,DEPDC1B,SMARCA5,HSPA5,TOMM20,PIAS1,FBXW7,RAB9A,SIRT7,SOD1,RPA3,BAP1,HECTD1,FGFR1,LMNA,RPA2,ATG16L1,CDC5L,TES,RCHY1,CD274,CTDSPL2,MPPED2,GRSF1,DPP4,NUP107,RING1,HAPSTR1,MAP1B,NUPR1,CBX3,AURKAIP1,ESR2,DLST,RAN,LMBR1L,TMEM100,SP1,BRCA1,LMNB1,FAS,ARHGAP19,BAG3,CASP4,CUL3,SFN,RAB11A,MYC,COIL,STAU1,ARHGEF39,ADRB2,PHB2,UCHL3,HSPA8,HDAC5,PPARG,BET1,TOMM22,NUP62,COX14,NUP35,EGLN3,KRT8,EED,PHB1,HSPB1,PEX3,CTNNB1,WDR11,XPO1,IFI16,SSRP1,KRAS,G3BP1,RNF126,HDAC11,CHMP4C,PDHA1,EZH2,JUN,SOX2,NUP153,TUBA1A,DHX38,RANBP1,RAF1 |
| 3.359e-04 | -8.00 | positive regulation of smooth muscle cell proliferation | biological process | GO:0048661 | 100 | 46 | 18204 | 5365 |
JAK2,MNAT1,BMPR1A,STAT1,TERT,MIR301A,NPY5R,MIR448,MIR20A,MIR214,MIR17,GJA1,PIK3R1,MIR208A,IRAK4,MIR222,GNAI2,MYD88,AIF1,MIR130A,MIR221,MIR146A,MIR21,HBEGF,PIK3CA,MDM2,CCL5,TNF,IGF1,FOXP1,IL10,CX3CL1,IL6,IGF1R,PHB1,IL13,ADAMTS1,MIR135B,MMP9,JUN,IL18,AKT1,SRC,CDH13,ITGA2,TLR4 |
| 3.363e-04 | -8.00 | CD99 (CD99 molecule (Xg blood group)) | protein interactions | 4267 | 66 | 32 | 19454 | 5460 |
LAMP3,DNAJC5,LAMP2,RAB2A,RAB11A,RAB5C,UBE2H,RHOG,LAMTOR1,RHOB,GJA1,RAC2,SGTA,RAB35,HRAS,PPIA,CAV1,ARF6,HNRNPL,RHOJ,RHOH,CDC42,FTH1,ARL15,RND3,RAB4A,SLC16A1,DERL1,COX8A,PMAIP1,STX7,KRAS |
| 3.363e-04 | -8.00 | ZFP62 (ZFP62 zinc finger protein) | protein interactions | 643836 | 66 | 32 | 19454 | 5460 |
RPL7A,ZNF668,RPL7,RPL13A,LYAR,DKC1,SRPK2,RPL19,ESR2,SRP14,KRR1,RPL37A,FGFBP1,PRKRA,RPS9,APOBEC3C,RBM34,RPLP0,MACROH2A2,FGF17,H1-3,RPL15,FGF13,DGCR8,NPM3,COIL,SRSF4,RPL28,SSRP1,RPL17,PPAN,RNF113A |
| 3.363e-04 | -8.00 | PPAT (phosphoribosyl pyrophosphate amidotransferase) | protein interactions | 5471 | 66 | 32 | 19454 | 5460 |
ARHGAP1,SHMT1,RPA2,CRY1,MEA1,RPA3,NUDT5,PRPS1,KRAS,B2M,HDAC3,STAU1,MCM3,CARS1,CIAO1,CUL3,HAX1,UBE2H,RIT1,ILK,FBXW11,TYMS,CCNF,PHB1,SMURF1,EGLN3,SELENOI,G6PD,ESR2,SNX2,PPAT,TENT5C |
| 3.363e-04 | -8.00 | PHF19 (PHD finger protein 19) | protein interactions | 26147 | 66 | 32 | 19454 | 5460 |
SNIP1,DCTN3,RAP2A,PICK1,KDM1A,H3C1,RBBP7,PHF1,THAP1,CHAMP1,CAMK1,EZH2,PSMC3,RBM5,EZH1,PELP1,HRAS,GTF2F1,EED,RANGRF,RBBP4,GSTCD,SRC,MALSU1,INO80E,IFI35,GAPDH,SUV39H1,TUFM,THAP7,CSNK2A1,EPOP |
| 3.363e-04 | -8.00 | RUNX1 (RUNX family transcription factor 1) | protein interactions | 861 | 295 | 110 | 19454 | 5460 |
HGS,SMARCB1,MTA2,HDAC11,EEF2,ELF1,CSTF2T,SOX2,JUN,VDR,PICK1,EWSR1,PRDM4,PABPC1,ARGLU1,DDX1,TRAF6,CTNNB1,ATG7,NDC80,DHX15,LRWD1,BRD9,PSMB4,SIN3A,CBFB,USP39,CTBP1,ACTL6A,CCND3,EP300,EMG1,DDX5,TRIM5,HSPA8,FOS,WBP2,LMNB1,BRCA1,GCC1,TAFAZZIN,BAG3,BTF3,CNRIP1,MYC,CREBBP,PRRC2A,MAD2L2,B4GAT1,DYNLL1,MED17,ACTB,SIAH1,EIF4A2,INTS10,PRMT5,SNRPD1,FOXP3,APEH,TFRC,SMAD1,NDST1,ZMYM4,EEF1A1,RPAP2,METTL26,TOLLIP,DHX9,FAF1,MPPED2,SNRNP70,NR4A2,SUV39H1,LRRC40,TLE1,RBFOX3,CDK9,CDK6,UBP1,SMAD3,WDCP,SYNCRIP,RAG1,RARS1,WWP1,ZNF326,CDK1,LMNA,CCND1,HSPA5,HDAC3,LCP1,PML,FAM222B,CDKN2AIP,IGF2BP1,SMAD2,EIF3G,GMPS,NONO,AR,RUNX1,CDC16,VPS39,VIRMA,SMAD5,GSK3A,TUBA1B,STUB1,PSPC1 |
| 3.383e-04 | -7.99 | PUM3 (pumilio RNA binding family member 3) | protein interactions | 9933 | 246 | 94 | 19454 | 5460 |
LYAR,NOP58,DHX15,MRTO4,SRSF1,RPL8,HP1BP3,EED,DDX23,IFI16,DDRGK1,HMGN4,H1-6,RPL28,PPAN,RPL31,RPS24,RPL18,MAGEB10,RAF1,SOX2,MAK16,H1-3,RPF1,RPL35,RPL7L1,ZCCHC7,RPL10,PRRC2A,ESR2,FAU,RPL37A,FTSJ3,LMNB1,NSA2,H1-1,CUL3,MYC,ZNF668,THAP7,NOP53,STAU1,MED23,H1-5,RPL35A,SURF6,DKC1,RPL32,KRR1,RPL12,SRP14,LDLR,RPL10A,NOL12,MOV10,RPL17,SNIP1,RPL3,RPL23A,RBM34,LLPH,HBP1,ILF2,RPL15,RPL13A,SRPK2,SMURF1,ZNF330,PRKRA,FGFBP1,UBE2H,RPL7A,RPF2,RPL26,RPL4,DGCR8,NPM3,UTP23,AATF,BRIX1,SIRT7,NLE1,RPA3,RPL27,MTDH,RNF113A,LMNA,RPA2,HPS6,MACROH2A2,RPLP0,RPL26L1,RPS14,FGF13 |
| 3.384e-04 | -7.99 | regulation of cell activation | biological process | GO:0050865 | 630 | 225 | 18204 | 5365 |
FGL2,PTPN11,RNF41,TLR4,CD40LG,LEP,CD200,NECTIN2,THY1,PRDX2,RAC2,IL18,NKAP,SRC,CLEC7A,IL21,CYGB,IL13,PIK3CA,CD47,SDC4,ACTL6B,IFNG,CTSC,IDO1,FUNDC2,TNFRSF9,F11R,GPNMB,PRKCQ,TNFAIP8L2,IRF1,B2M,IL23A,UBASH3B,EXOSC3,DROSHA,CHRNB2,IL7,FBXO7,TICAM1,EPO,C1QTNF1,HMCES,IL15,LGALS3,SMARCB1,SIT1,PRELID1,MIR181C,FCGR2B,EMILIN1,STAP1,BATF,CD226,DUSP10,MZB1,AGER,PYCARD,SYK,CD1D,HMGB1,CD40,BCL6,HFE,KMT5B,MIR145,TESPA1,KLRC2,RHBDD3,GPAM,YES1,TFRC,RPS3,SELENOK,TNF,VSIR,TWSG1,CD2,ACTB,XCL1,IL10,DUSP22,SLC39A10,SFTPD,AIF1,CCL19,F2,CCR2,IRF4,DPP4,RHOH,CTLA4,CYRIB,PLSCR1,PDCD1LG2,PRKCA,CD38,THBD,NLRP3,TRAF6,RAG1,IL15RA,ARG2,CGAS,TBC1D10C,CCL2,ICOS,TNFRSF14,IL2RA,CDKN1A,SPHK2,BTN2A2,IL6ST,PRNP,KLHL25,TNFSF8,PELI1,SMARCE1,PNP,MIF,CD83,CCL3,JUNB,SASH3,ACTL6A,DHPS,LILRB1,LDLR,BCL10,HSPD1,HTR2A,FOXP3,IL12A,CD274,IL6,CSK,SFRP1,GP9,MIR142,CD86,GNAQ,CCL5,MMP14,SLC7A1,IL12B,FCER1G,SOS2,MIR185,FGR,CD46,LILRA2,LILRB4,CD81,CD9,MIR30B,IFNA2,MIR21,CD4,PLPP6,INHA,RUNX1,IL20RB,SOCS5,TLR9,SMARCD3,TNFRSF1B,IL4,LST1,TACR1,ZBTB16,MYD88,CBFB,CD80,CD28,BLOC1S3,MEF2C,TYROBP,CAV1,IFNB1,MAD2L2,WNT10B,RC3H2,STAT6,TLR6,CCR7,TNFSF18,PTPN22,PPP3CA,GCLC,IL1B,AKT1,SHLD1,TNFAIP3,FGF10,CTNNB1,TOX,IL2RG,NCK1,CD209,ACTA2,IGF1,EP300,KARS1,IL1A,DUSP3,EFNB1,MIR130A,IL2,TGFBR2,CNR1,DLG1,SOD1,KLRD1,CCL21,LMO4,TNFSF13,XBP1,NDFIP1,BAD,JAK2,IL5,PLA2G5,TIRAP,MIR125A |
| 3.394e-04 | -7.99 | MAPK1 (mitogen-activated protein kinase 1) | protein interactions | 5594 | 493 | 173 | 19454 | 5460 |
LAMTOR3,RMDN3,ILK,SP1,HSP90AA1,NTRK3,BRCA1,BLVRA,GRB10,RGS19,HSCB,DUSP9,PPARG,STXBP1,RND2,NDE1,MAPKAPK5,CACYBP,EGLN3,NTMT1,KRT8,XPO5,GJA1,PHB1,PTPN5,DYRK1B,HMGA1,FHL3,PLCB1,SLC25A23,UBE3A,HECTD3,PRPSAP1,CDKN2C,GADD45A,RPS11,EZH2,TULP3,NUP153,JUN,ZNF263,RAF1,TPD52,VDR,RPL22,DUSP10,VIRMA,FERMT2,PTEN,METAP2,CCNF,GAB1,SMAD2,PEA15,TXNIP,IFNAR1,AR,PPP1CC,RUNX1,DHPS,RALB,CTSD,BRIX1,HMGB1,DGCR8,GTF2I,SQSTM1,DVL2,RPA3,WTAP,PTP4A2,CCND1,WDR83,CAV1,PRNP,DCUN1D1,PPP1R18,RB1,MAP2K6,WDCP,PTPN1,SMAD3,GOLPH3L,HDAC6,LAMTOR2,CTNND1,POLR2G,SMAD1,MAP2K3,PPARA,ESR2,LMBR1L,COP1,H1-10,RPS6KA4,CDKN2D,CREBBP,MYC,ITGAV,EP300,HERC3,FOS,PEBP1,ZBTB42,MAP2K1,PAK2,FRS3,ELK4,ELK1,MITF,PGR,CORO1C,DUSP6,LRRC4,MAPK4,MDFI,VDAC1,PSMA1,KRAS,CRKL,MSX2,H1-3,SRC,DUSP3,PRKCE,STAT5A,DAPK1,UBE2H,ATP1A1,PTTG1,SPOP,MECP2,GORASP2,MTPN,IFI35,BCL6,PRDX6,PML,SNCG,PRKCA,GSTP1,HEXIM1,IPP,RPRD1B,RPA2,NEK2,SNRNP27,SURF6,NKAP,MCL1,IER3,ATP6V1D,H2AC4,SHC1,TUBG1,NR4A2,SMAD4,GAPDH,MZT2B,CSNK2A1,FCGR2B,KARS1,CAPZA1,DUSP19,TNKS2,ABCE1,RNF8,CAPN2,NHERF1,TFCP2,DUSP1,CDK4,TP53 |
| 3.407e-04 | -7.98 | WSB2 (WD repeat and SOCS box containing 2) | protein interactions | 55884 | 85 | 39 | 19454 | 5460 |
PFDN2,HSP90AA1,H1-1,PFDN6,BCL2L1,RPL10A,RPL7A,ST13,PCCB,TXN,RPS16,RPL13A,UBB,RPL22,CCDC42,RPS3,AIP,RPL32,RPS12,RPS9,RPN1,EZH2,RNF7,HSP90B1,CYB5B,RPS14,CCT5,ZC3H14,NUDCD3,PHB2,TTC4,VDAC1,ARF4,RPS4X,SNIP1,TXNL1,DERL1,AKAP1,PDIA6 |
| 3.407e-04 | -7.98 | BLTP3A (bridge-like lipid transfer protein family member 3A) | protein interactions | 54887 | 85 | 39 | 19454 | 5460 |
RAB4A,RPA2,STK16,BORCS8,ATG16L1,DIO3,RFXANK,RND2,RAB3B,UQCC2,RPA3,RAB9A,RAB5A,RAB30,PCNA,LAMTOR1,RHOG,FIS1,HNRNPD,RAB11A,HMGA1,LAMP2,ATG9A,CREB3,ACTL6B,DNAJC5,LAMP3,H2BC9,RHOH,RAB14,SSH3,ARF6,HMG20A,VIRMA,STX6,ARL10,RAB35,SYNCRIP,TSG101 |
| 3.414e-04 | -7.98 | nucleic acid biosynthetic process | biological process | GO:0141187 | 627 | 224 | 18204 | 5365 |
FUBP3,MTERF2,PRMT5,SMAD4,ZNF345,ADRB2,PROX1,PRDM4,NFKBIB,CHRAC1,CEBPE,NPM3,DHX9,PCNA,VDR,SNAPC1,TWNK,CTNNB1,RPRD1B,TCEANC2,RFC3,DPY30,POLB,ENY2,DR1,DKC1,EP300,SKIC8,SIRT7,GTF2H5,GTF2B,IL2,POLA2,CYTL1,CDK12,HIRA,TOPORS,SNAPC5,AR,CDK7,TRIM24,RRN3,TERC,SUB1,XBP1,SART3,SOX9,POLL,MTF1,KPNA6,POLR1D,RPRD1A,TAF11,PPP5C,JAK2,MED31,SMAD1,NHP2,MACROH2A1,NR1H2,HSP90AA1,NFIL3,USP15,MED21,BARX2,GTF2F2,POLR3GL,SMN1,COPS2,POLR2D,FOXP3,CREB1,GTF2F1,RCHY1,PADI2,MARS1,NKX3-2,POLD4,DNTT,WWP2,POLR3B,POLR2C,POLR2I,WDR82,APOBEC3F,RAMAC,CDC73,IRF9,PAAF1,HDAC3,ZMPSTE24,THAP1,TAF5L,CREBL2,SMAD2,GTF2H4,TAF2,CD28,HSP90AB1,CBFB,POLR3F,CDKN2D,POLR3H,NCAPG2,GTF2A1,LIG3,MED27,MED29,PAX6,GPBP1L1,MAD2L2,SNAPC3,WNT10B,PCLAF,SGF29,HINFP,S100A10,EAF2,PKNOX1,MED11,POLDIP2,FOXA3,GTF2A2,MED22,APOBEC3C,SSU72,MED30,MED10,PIR,BCL6,PLAC8,MSX1,MED9,TRMT112,TEX12,TAF9,POLD2,PPP1R1B,PHB1,ELOC,MED23,CMTR1,TCEA1,CCNH,APOBEC3A,MRPL12,LDB1,NDP,CEBPG,GTF3C3,TERT,GTF2E2,NFKB1,OGG1,RB1,TYMS,SUPT3H,TFB1M,MED4,FOS,SUPT5H,TFCP2,NFYA,WBP2,RPAP2,SPHK2,CDK9,POLR2B,TCOF1,POLR1B,KLF4,SQSTM1,POLR2G,ATF4,POLR2F,POLE3,POLR1H,HELT,GTF2H2,CMTR2,ATXN1L,PTGES3,SMARCA5,WRAP53,SRC,SUPT4H1,MEF2A,ELOF1,EPOP,VPS72,DDX5,NCBP2,ADRM1,TAF10,TAF7,DTL,APEX1,MED17,TP53,ERCC3,MLF1,POLE4,NIBAN2,SNAPC2,PPARG,DEK,CCNA2,PIK3R1,GTF2IRD1,IRF1,DRAP1,TCEA2,GTF2I,GTF3C4,PRIM2,MNAT1,POLR2L,GTF2E1,NR4A2,IVNS1ABP,BCL9,SMARCB1,RRM1,EGR1 |
| 3.421e-04 | -7.98 | PPFIBP1 (PPFIA binding protein 1) | protein interactions | 8496 | 171 | 69 | 19454 | 5460 |
CDKN1A,RND2,CDC42,CLDN4,ARL15,FGFR1,CPLX2,RAB5A,RAB9A,RHOU,TACR3,STX7,DNAJC5,BTF3,CUL3,SFN,GPR17,RAB11A,RAB2A,RHOB,CHCHD4,YWHAZ,LAMTOR1,GSK3A,ENO1,S100A6,VIRMA,ESR2,DYNLL1,RHOJ,RAPGEF5,PPP2R1A,TP53,COMTD1,SNAP29,B3GNT2,RND3,PPFIA2,NTRK2,S100B,FLOT1,ARF4,TOLLIP,KRAS,LAMP3,YWHAH,PPFIBP1,YWHAG,RAB5C,LAMP2,MOV10,UBXN6,YWHAB,SMAD4,RHOG,RAC2,PPFIA3,GJA1,ARL10,EEF1AKMT3,RAB35,HRAS,CAV1,LMAN1,DIRAS3,STX6,PRNP,RHOH,ARF6 |
| 3.432e-04 | -7.98 | endometrioid | COSMIC cancer mutations | endometrioid | 21 | 14 | 16828 | 4835 |
KRAS,PIK3R1,IDH1,FGFR1,PIK3CA,PTEN,DICER1,KIT,MET,CTNNB1,JAK2,AKT1,FBXW7,IDH2 |
| 3.432e-04 | -7.98 | groin | COSMIC cancer mutations | groin | 21 | 14 | 16828 | 4835 |
PIK3CA,TERT,PTEN,CTNNB1,KIT,GNA11,TP53,AKT1,JAK2,GNAQ,KRAS,HRAS,FBXO11,IDH1 |
| 3.432e-04 | -7.98 | ovary-low_malignant_potential_(borderline)_tumour-endometrioid | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-endometrioid | 21 | 14 | 16828 | 4835 |
IDH2,FBXW7,AKT1,JAK2,CTNNB1,MET,KIT,DICER1,PTEN,PIK3CA,FGFR1,IDH1,PIK3R1,KRAS |
| 3.457e-04 | -7.97 | positive regulation of interleukin-2 production | biological process | GO:0032743 | 34 | 20 | 18204 | 5365 |
TRAF2,IRF4,CLEC7A,CD28,CCR2,CD80,CD4,PDE4B,CD86,RPS3,SPTBN1,SASH3,STOML2,CD83,RUNX1,PNP,TRAF6,IL1A,PRKCQ,IL1B |
| 3.468e-04 | -7.97 | Separation of Sister Chromatids | REACTOME pathways | R-HSA-2467813 | 168 | 74 | 10285 | 3229 |
PSMA1,PSMC3,SKA2,MIS12,PSMD4,ANAPC11,PPP1CC,RPS27A,ANAPC2,PSMD6,ANAPC15,PSMB4,CDC23,CENPM,PSME2,UBE2D1,PTTG1,ANAPC4,CENPL,PSMB9,MIR484,NUF2,SEM1,KIF2A,CENPP,PPP2CB,NUP107,MAD2L1,XPO1,PSMA6,PSMD1,PSMB2,MAPRE1,B9D2,NUP37,PSMD12,PSMC1,NDC80,ANAPC16,SEC13,RAD21,PSMD14,UBB,PPP2R1A,CDC26,UBA52,PSME1,DSN1,PSMD10,PSMD7,PAFAH1B1,PSMB11,PSMC5,PSMB10,PSMA5,PSMA4,SPC24,PSMB3,PSMA2,PSMB6,PPP2R5E,BUB3,CDC20,PSMB1,NDE1,CDC16,PSMD3,SKA1,PSMB7,PSMC4,PPP2R5A,PSMB5,PSMA3,BIRC5 |
| 3.470e-04 | -7.97 | TLN1 (talin 1) | protein interactions | 7094 | 234 | 90 | 19454 | 5460 |
RPA3,BAP1,SIRT7,PML,CERS2,SNRNP27,CFTR,GTF2H4,ATG16L1,HNRNPH3,RPA2,JUP,PSMC5,CCNF,SMURF1,ROCK1,VIRMA,SRC,KCTD9,TXNDC12,CARS1,FMO1,ATP1A1,UBE2H,BICD2,SEPTIN7,HAPSTR1,FAF1,GLUL,PRDX4,EEF1A1,TP53,ADD1,TES,SYNCRIP,ZBTB2,CDC5L,RPL35A,PRNP,MRPL50,GAPDH,DAG1,MOV10,HSPA8,EP300,EMC1,STAU1,SEC62,PPARG,LMBR1L,ESR2,APEX1,HMGCS1,SNRPB,MYC,HSP90AA1,SP1,BLVRA,BRCA1,CYP1A1,ZC3H7A,CDK5,BAG2,RNASEH2C,HNRNPDL,SAR1B,ROCK2,TUBA1A,GTF2E2,RAF1,TOP3B,B3GNT2,E2F4,HEXA,ITGB5,AZIN2,MOB3C,EZH2,PLS3,LRRC61,HSP90AB1,WIF1,RGCC,TCP1,SUMO2,CTNNB1,HNRNPD,NAB2,MED4,AGR2 |
| 3.476e-04 | -7.96 | H1-7 (H1.7 linker histone) | protein interactions | 341567 | 177 | 71 | 19454 | 5460 |
RSL24D1,MRPS21,MRPL23,MRPS28,MRPL13,ZNF22,PELP1,RPS3,RPS5,NSA2,MRPS16,ZCRB1,FTSJ3,MRPS25,ZNF668,MRPL16,ZSCAN25,NOP16,AATF,MRPL20,BRIX1,MRPS7,RPS15,MRPL17,MRPL41,MRPL57,NOP53,MRPL40,SF3B1,MRPL34,RBM23,RPL26L1,MRPS34,MRPS18A,MRPL10,MDM2,MALSU1,MRPL24,RPS10,MRPL50,HP1BP3,MRPS9,KRR1,NOL12,RPS2,MRPS26,H2BC17,MRPL18,ZCCHC9,MPHOSPH10,MRPL9,E4F1,NGDN,CMSS1,DDX50,SPATS2L,MRPS35,MRPS18C,MRPL22,RPL17,MRPS33,NOC4L,MRPS18B,MRPS11,MRPL52,MRPL33,MRPL49,MRPL51,LBR,MRPL47,MRPL11 |
| 3.476e-04 | -7.96 | KIFBP (kinesin family binding protein) | protein interactions | 26128 | 177 | 71 | 19454 | 5460 |
RTF2,RPA2,QRSL1,ADNP,CDC42,RFXANK,DET1,EIF3J,NDE1,ATG16L1,COIL,SAP18,HSCB,KDM1A,STAU1,SNX33,HADHA,PYM1,RPA3,OSGEP,KIF3C,ILK,CALU,MAPRE1,NIF3L1,FAS,DCAF4,PRKACB,PPP1CC,GORASP2,GSTK1,PLEKHF1,PSMD4,DHRS13,GTF2F1,MACROH2A1,DOK4,LMBR1L,DPEP1,STX12,HBP1,SH3GLB1,TUBB4B,ACTR2,ACTR1A,KIF1C,COPS4,AHCYL1,ANP32B,PTGES3,UFM1,GNL1,THRAP3,ZC3H7A,COX8A,BCL7B,MAP1B,COPS5,NT5C2,UBXN6,MOV10,SAV1,LMAN1,PTP4A3,ZBTB2,KIF3B,SPPL3,COPS2,KRT8,SIN3A,EEF1AKMT3 |
| 3.477e-04 | -7.96 | cellular response to chemical stress | biological process | GO:0062197 | 285 | 111 | 18204 | 5365 |
GPR37,PIK3CA,MDM2,TP53,CYGB,TP53INP1,STAU1,PRKRA,IL6,MIR34A,MIR107,SOD2,PPIA,DAPK1,MMP9,PRDX3,PRDX1,GPX7,PCGF2,JUN,PRDX2,SRC,MPV17,HSPA8,CDK1,SOD3,KLF4,OXSR1,ATF4,TRIM21,GPR37L1,DDIT3,NR4A2,CAV1,NFE2L2,EPO,SIN3A,CHCHD4,EDNRA,SRXN1,CD36,PYCR1,EZH2,TSPO,HTRA2,NQO1,ATG7,VKORC1L1,STK24,RWDD1,SESN2,SERPINB6,FXN,HM13,SELENON,GPX5,ARL6IP5,ROMO1,SLC7A11,PDCD10,SLC2A1,SLC1A1,GJB2,TNFAIP3,PCNA,TXN,ATP1A1,NUDT2,MT3,GPX1,IL18BP,RPS3,TOP2B,TMIGD1,PYCR2,AKT1,AIFM1,GLRX2,PEX13,TBC1D24,AKR1B1,HDAC6,FBP1,STAT6,CAB39,PRR5L,PYCARD,SELENOS,RHOB,OSER1,CHCHD2,CRYGD,FOS,SLC25A24,EIF2S1,CCS,MAP1LC3A,OGG1,LRRC8D,NLRP3,FAS,G6PD,CYP1B1,BECN1,LRRC8C,STK26,MIRLET7B,AIF1,XRCC5,SOD1,PPIF |
| 3.481e-04 | -7.96 | positive regulation of protein localization | biological process | GO:1903829 | 480 | 176 | 18204 | 5365 |
CDK1,DMAP1,AKT2,PDCD5,CDK5R1,SNAP25,PARD6A,VEGFC,PRNP,CLIP3,HSP90AA1,DPP10,KCNB1,ACSL4,MIR223,CDC42,PPIA,PTP4A3,MIEF1,FERMT2,EFCAB7,JAK1,PCK2,PLCB1,RBM22,HTRA2,RTN4,HDAC3,ATP2C1,PSEN1,CD81,SFN,SAR1B,MAVS,ACHE,MEPCE,TYROBP,BAP1,CNPY4,HSP90AB1,AKT1,TGFB3,IL1B,GAS8,WNT7A,CCT7,CREBBP,PFKFB2,SNX33,AGR2,IL1A,CHP1,TGFB2,OSBP,IGF1,DKC1,EP300,PDCD10,TRIM8,TCAF2,RAB29,HYAL2,BAG3,ANP32B,GHRL,RIC3,MSN,DLG1,CRKL,FIS1,NR1H2,ATP2B4,CCT2,OR51E2,CHRM1,EDEM1,JAK2,RER1,TSG101,BAD,RAMP3,CDK5RAP3,PRKCB,PRKCE,GSK3A,STAC3,SRC,WRAP53,PPID,KCNJ11,RAC2,TM9SF4,TLR4,LEP,LRRC8A,SQSTM1,TOMM70,HUWE1,TMEM30A,IFNG,PIK3CA,MDM2,PGRMC1,DYNLL1,OAZ1,IL13,UBE2D3,TNFAIP6,HPCA,OAZ3,JUP,SESN2,RHOG,PIK3R1,RAN,PIK3R2,STOM,CAMK1,CD247,TCP1,PPARG,CLSTN3,CCT5,TOMM7,UBL5,LGALS3,NF2,VRK1,RHOU,VPS28,CTDSPL2,EPHA2,CDK5,GOLPH3L,ORMDL3,RANGRF,ZDHHC8,ABHD17A,CCT8,STK11,HRAS,FBXW7,OAZ2,PRR5L,SMAD3,ROCK2,SPTBN1,DDRGK1,APBB3,TNF,TFRC,UBE2L3,TLR2,NLGN2,LAMTOR1,CFTR,CD2AP,CD38,C2CD2L,TMEM97,ARF6,PIAS1,F2,EDEM2,CDK9,SH3GLB1,SYBU,NUP62,VAMP2,HCLS1,SRI,GNA11,TESK1,CHRM3,CACNB4,TERT |
| 3.485e-04 | -7.96 | regulation of protein modification by small protein conjugation or removal | biological process | GO:1903320 | 244 | 97 | 18204 | 5365 |
SQSTM1,TRIM21,PELI1,HUWE1,HSP90AA1,RWDD3,ANGPT1,BCL10,BAG2,COPS2,CAMLG,UBB,FZR1,PPIA,CDC20,RCHY1,COPS7A,UBE3A,SVBP,SPOPL,MAGEC2,RPL23,RPS2,DNAJB2,UBE2S,BEX3,UBE2I,UFL1,COPS4,CDKN1B,HDAC3,CUL3,HSPA5,TSPO,HSP90AB1,IVNS1ABP,TRIM44,NMI,EGR1,RBCK1,TICAM1,CAV1,MAD2L2,NSMCE3,TANK,ISG15,RPS7,GABARAP,FBXW7,MINAR1,CDK5,SIAH2,AKT1,NOP53,VPS28,STUB1,UBE2V2,PTPN22,HMG20A,FAM107A,UBE2V1,GCLC,BIRC2,RPS3,COPS7B,TNFAIP3,CTNNB1,UBE2L3,MUL1,SIRT7,CHP1,MIR101-1,DCUN1D5,UBE2N,UBE2D1,SKP1,PIAS1,PLAA,TOPORS,ARRDC3,NDFIP1,TRAF6,TOLLIP,COPS5,DERL1,WBP1L,PRKCE,CRY1,GSK3A,CDK5RAP3,DCUN1D3,KDM1A,DCUN1D1,PTEN,PHF23,MAD2L1,PSMD10 |
| 3.487e-04 | -7.96 | YTHDF2 (YTH N6-methyladenosine RNA binding protein F2) | protein interactions | 51441 | 286 | 107 | 19454 | 5460 |
COPS5,ENY2,MOV10,SMG8,SNRNP70,LDLR,SMAD3,SYNCRIP,EIF4E2,CAND1,FZR1,TP53,TNRC6C,FURIN,SEPTIN7,HAPSTR1,FAF1,GARRE1,MEPCE,CNOT6L,CNOT7,TGFBR2,USP14,CEP85,IGF2BP1,NRP1,PAIP2,CASC3,UBE2H,RC3H2,PHAX,RTRAF,PTEN,RPS20,CCNF,SMAP2,GABRA1,AGO1,CFTR,RBMS2,DYRK2,RPA2,LSM12,RNF113A,SMG5,RPA3,BAP1,PML,EIF4E,BCL6,FBXW7,CPEB1,YWHAH,YWHAG,XPO1,CNOT8,HNRNPA1,MAP3K14,DDRGK1,HMBS,CNOT2,RB1CC1,SLC25A28,CBFB,PHB1,FUBP3,CEP19,NUP35,FAM98A,KCTD10,SOX2,TOP3B,RAF1,MACO1,B3GNT2,GTPBP1,GLE1,ZC3H7A,UBE3A,RTCB,ZYX,LSM14A,PABPC1,PFDN1,G3BP1,MYC,CREBBP,USP13,CUL3,LSM14B,DCAF4,CNOT6,PRRC2A,USP5,RPL10,EIF4A2,NUDT3,NUFIP2,EMC9,LARP4B,AKAP1,MCRIP2,G3BP2,B9D2,FXR2,STAU1,YTHDF1 |
| 3.488e-04 | -7.96 | EPB41L3 (erythrocyte membrane protein band 4.1 like 3) | protein interactions | 23136 | 231 | 89 | 19454 | 5460 |
RAB35,SNRPD3,LYAR,DHX15,ZCCHC10,DPY30,YWHAG,YWHAH,RHOG,MED4,YWHAB,MAGOH,HSPB1,UBE3A,KRAS,FLOT1,RAF1,FAF2,ZRANB2,ATXN1L,MIDEAS,PRMT5,FBXO22,DYNLL1,MYC,SNRPB,YWHAZ,HSPA8,PMAIP1,UCHL3,KRT222,STAU1,STX7,SAP18,IGSF21,ASB3,WDR77,SEC62,ARF6,EIF2B2,NKAP,DKC1,CDC5L,CAV1,ENY2,CSNK2A1,SMCHD1,BRD3,ABCE1,HUWE1,SCML1,PSEN1,KBTBD4,TBK1,KIF1C,TP53,TAF1D,PLA2G12A,TNFAIP8L1,DISC1,TAF2,EIF4A3,CSNK2B,NDN,RHOJ,SMURF1,VIRMA,DDAH2,PIP4K2C,PPIG,AP3S2,UBE2H,RHOU,GID8,PML,SIRT7,DERL1,KDM1A,RPS15,CERS2,CXXC1,SPTBN1,SNRPN,CDC42,ZCCHC17,IDH2,ARL15,AGAP1,HECTD1 |
| 3.495e-04 | -7.96 | SUGP1 (SURP and G-patch domain containing 1) | protein interactions | 57794 | 136 | 57 | 19454 | 5460 |
AR,SNRPB,MYC,SERPINH1,SNRPD2,UBE2I,MRPL53,FAM177A1,SF3B6,VDAC2,EIF4A3,EZH1,UBE2L3,SNRPB2,ESR2,SNX3,SNRNP40,ATG16L1,SF3A1,SPR,TFIP11,RPA2,LMNA,STOM,SF3B1,NUP50,SNRPA,RPA3,PML,STX7,PYGB,CERS6,XPO1,PPIB,RAB5C,RBM17,MIR1-1,POU5F1,DDX23,THY1,ACBD7,DHX15,CDK17,SNRPA1,MIRLET7G,PPIF,KBTBD4,COMTD1,UBL4A,NDUFA2,CBX3,ZC3H11A,PQBP1,RIGI,ASF1A,SRPRB,VDAC1 |
| 3.495e-04 | -7.96 | TLE2 (TLE family member 2, transcriptional corepressor) | protein interactions | 7089 | 136 | 57 | 19454 | 5460 |
ANKRD50,EMX2,RPL23,DNAJC7,TLE1,PRPF19,TCP1,SPPL3,RPS16,CCT7,RPL32,WDCP,AIP,RPL18,RPS11,CCT5,RPSA,RPS7,MSX2,TTC4,VDAC1,RPS13,RPS4X,CCT8,HSPD1,BAG2,DNAJB4,CCDC22,DCAF4,CCT2,PFDN6,FOXA3,CEP85,PYCR1,PCCB,TUFM,RPL26,ATP5F1A,RUNX1,RPL13A,RPL22,MAD2L2,STUB1,RPS3,RPS12,RPS9,GANAB,HSP90B1,ACAA2,PAX9,RPL27A,RPS14,PCK2,MSX1,HMGB1,MARS1,HSPA8 |
| 3.495e-04 | -7.96 | NIBAN2 (niban apoptosis regulator 2) | protein interactions | 64855 | 136 | 57 | 19454 | 5460 |
PAPOLA,RAB11A,DNAJC5,LAMTOR1,RHOB,NTRK3,GTF2A1,TSN,RHOJ,IDE,ARHGAP1,SHMT1,CDC42,RPA2,PAK2,FGFR1,STX17,RHOU,PML,HSPA8,RAB5A,NUP50,RAB9A,STAU1,STX7,LAMP2,VPS26A,RHOG,AGR2,AGPAT1,RAB35,HRAS,FBXO32,EEF1AKMT3,GJA1,CORO1C,ARF6,SUMO2,SNX2,RHOH,DIRAS3,STX6,CDC5L,CAV1,RAF1,E2F4,RND3,CCR1,ZYX,AKT2,GLUL,ERO1A,IGF1R,KRAS,EPHA4,FLOT1,RIGI |
| 3.499e-04 | -7.96 | USP47 (ubiquitin specific peptidase 47) | protein interactions | 55031 | 180 | 72 | 19454 | 5460 |
RPRD1B,QRSL1,PTP4A2,PAK2,RPA2,PPP1R8,RND2,ETF1,SMC4,DDI1,SKP1,CRYZ,HELLS,RPA3,SIRT7,TCEA1,FBXW11,STN1,ALKBH5,ALDH1L1,PTPN11,HNRNPC,HPF1,SNX3,VIRMA,INPP5K,VAMP3,CCNF,TBCCD1,TUBA1B,CYB5R3,EFHD2,DNAJC2,IK,CHMP4C,RBPJ,MTA2,PPME1,MOB3C,NAA15,FEN1,LYPLA1,RBM12,MED9,TULP3,CNOT7,CTNNBL1,BACH1,VRK1,FGF12,RUVBL1,SATB1,PHF1,SAR1B,RAD21,MDC1,NSDHL,PPP1R12A,PDIA6,POLB,MED29,TRAF6,RPS2,USP15,GMPPB,XPO1,HDAC6,LRRC40,EGLN3,NUP35,WDR44,RPRD1A |
| 3.506e-04 | -7.96 | Golgi vesicle transport | biological process | GO:0048193 | 288 | 112 | 18204 | 5365 |
RAB13,KIF1C,EXOC5,TRAPPC3,YIPF5,NAPA,VPS54,EXOC8,VAMP3,PICK1,TRAPPC10,USE1,SNAP23,LMAN1,RP2,STX6,SNX12,BCAP29,TEX261,RAB31,TRAPPC6A,EXOC2,EHD3,CIDEB,VAMP2,TFG,COPZ2,RER1,MYO1B,TMED9,PREB,TMED4,RAB1B,NAPG,RAB14,GOLPH3L,RAB6A,SEC22A,RINT1,RANGRF,PITPNB,TMEM115,YKT6,RAB6B,VAMP7,RAB11A,RAB33B,KDELR2,SEC13,RAB29,SEC22B,RAB2A,SPTBN1,KLHL12,VAPB,AP2A1,CCDC22,YIPF4,TMED3,TRAPPC1,YIF1A,BET1,BICD2,ARCN1,STX17,VAMP5,SCFD1,AP3S2,EXOC1,SNX3,DNM2,TMED5,GABARAPL2,RABIF,SNX1,CUL3,SCAMP2,SYS1,COG1,VTI1B,TRAPPC3L,OPTN,TRAPPC4,KDELR1,TAPBP,RAB1A,GOLGA7,SAR1B,TRAPPC6B,SNX2,AP1AR,STX18,CNIH4,ARF4,TRAPPC2L,MIA2,TMED7,AP1G2,TMED1,TRAPPC13,CEP19,GOSR1,GOLGA5,GOSR2,SEC22C,STX10,SURF4,COPE,PREPL,SEC23A,ARFGAP3,STX5 |
| 3.511e-04 | -7.95 | INTFRNREGFCT | prints domains | PR00267 | 9 | 8 | 5227 | 1528 |
IRF6,IRF7,IRF8,IRF4,IRF2,IRF3,IRF1,IRF9 |
| 3.518e-04 | -7.95 | ASS1 (argininosuccinate synthase 1) | protein interactions | 445 | 183 | 73 | 19454 | 5460 |
PTPN1,MTAP,SUMO2,HNRNPL,TMPO,EMC4,COX5A,FAM20C,PRDX1,GAPDH,YWHAH,HDAC6,RPL23,NQO1,SFXN1,MAP1B,HSPD1,PC,HAPSTR1,OAZ3,RUVBL2,KPNA2,HSPE1,CA10,ETFB,MTCH2,B3GNT2,MVD,APOO,CTSA,CHMP4C,PIR,ENO1,OPTN,ACOX1,GNPDA1,RPGRIP1L,FBXO22,TXN,PRDX2,TAGLN2,LDHA,FAH,JAK2,VIRMA,LDHB,MPC1,NDUFAF2,MYC,RAB2A,SLC25A1,ATG3,ADK,HTRA2,OAT,CA2,TNFAIP8,RPA3,GFM1,PRDX6,HSPA8,PDHB,EMC1,MT2A,EIF4E,SPR,CAPN1,UQCRC1,RPA2,CNDP2,SCLT1,GIT2,EPHX1 |
| 3.521e-04 | -7.95 | FOXC1 (forkhead box C1) | protein interactions | 2296 | 225 | 87 | 19454 | 5460 |
TOP2B,RTCB,DHX9,BAG2,SRSF7,EWSR1,SATB1,RBBP7,FOXP4,SSRP1,PAX6,MSH6,RNF20,MCM6,GBE1,TP53,MAX,ELF1,DDX39A,SOX2,PPP2R1A,NHERF1,TFCP2,TUBB4B,MTA2,PPP2CB,SRSF1,UBP1,AIP,ETV6,CBFB,METTL6,CCAR2,HNRNPL,DHX15,HMG20A,TMPO,EGLN3,FOXC2,PRPF19,TPM3,HNRNPA1,SMCHD1,SNRNP70,DDX23,FOXP1,PEBP1,EP300,HSPA8,HMGB1,GTF2I,KDM1A,HNRNPA0,FOXP2,COIL,ADNP,CTBP1,FOXS1,HNRNPH3,PAX9,GSTP1,LIG3,PSPC1,CREB1,MACROH2A1,SNX3,SNRNP40,MATR3,BUB3,CEBPE,APEX1,DEK,PRMT6,SUB1,SMARCA5,HNF1B,MCM3,CAPG,NONO,RUNX1,SMARCE1,RNF40,LDB1,RC3H2,LMNB1,FBXW11,MECP2 |
| 3.529e-04 | -7.95 | POLR3E (RNA polymerase III subunit E) | protein interactions | 55718 | 99 | 44 | 19454 | 5460 |
POLR3F,POLR2I,POLR2B,BCCIP,RPRD1A,POLR2L,POLR3B,POLR2F,POLR3H,PFDN2,MED4,POLR1B,MAF1,PFDN6,CSNK2A1,PPP1CC,POLR3GL,KRAS,DNAAF10,PDRG1,TRIM52,GTF3C3,SLC25A14,POLR1H,SSRP1,SNRPA,PSME1,TMEM263,RPAP3,RUVBL2,RPA2,RPRD1B,PDHA1,POLR2C,POLR2G,SLC25A20,POLR2D,RBPJ,PIH1D1,TRMT1L,TBK1,RPAP2,PRDX3,POLR1D |
| 3.529e-04 | -7.95 | LMTK2 (lemur tyrosine kinase 2) | protein interactions | 22853 | 99 | 44 | 19454 | 5460 |
EIF2S1,STX6,VIRMA,ESR2,FHIP1B,CAV1,UBE2N,DUSP6,GJA1,XPO5,EIF2S2,MACROH2A1,LAMTOR1,MYO6,PPM1K,KARS1,SFN,PYCR2,STOML2,RAB11A,YWHAH,YWHAG,PPP1CC,RPS29,PPP1R2,STX7,FLOT1,SSRP1,DUSP19,SLC25A11,CDK5,ABCE1,DHX9,RAB9A,CCDC86,RAB4A,CDK5R1,KLC2,TOP3B,MTMR6,DUSP14,ATG16L1,PPP1CB,RAB6A |
| 3.529e-04 | -7.95 | URB2 (URB2 ribosome biogenesis homolog) | protein interactions | 9816 | 99 | 44 | 19454 | 5460 |
RPA3,SIRT7,STAU1,RPL4,CDC42,LMNA,APOBEC3C,RPA2,RPLP0,MACROH2A2,LMBR1L,EIF2AK2,ZNF330,FGFBP1,PRKRA,RPL13A,TAX1BP1,APLNR,ATP6AP2,ESR2,SRPK2,VIRMA,MYC,OPRM1,SCN3B,BAG3,MECP2,LMNB1,RPL31,FGF3,RPL23A,RPL3,RPS24,KRAS,RPL28,TP53,MGARP,RPL15,RBM34,AQP3,ILVBL,IFI16,CSNK2A1,ATG7 |
| 3.534e-04 | -7.95 | TATDN1 (TatD DNase domain containing 1) | protein interactions | 83940 | 53 | 27 | 19454 | 5460 |
GMDS,IRF2BP1,HNRNPL,CCT7,PPP5C,PSPC1,UBE2I,MSN,TSG101,CCT2,TAFAZZIN,PDCD10,XAF1,USP8,NSFL1C,PAFAH1B2,PPP1R2,UBE2K,NAE1,HSPB2,HSD17B6,HEXB,CAPN2,CCT5,PAFAH1B1,CMPK1,UBR7 |
| 3.534e-04 | -7.95 | CCDC92 (coiled-coil domain containing 92) | protein interactions | 80212 | 53 | 27 | 19454 | 5460 |
UBE3A,ZYX,PSMC1,PSMD12,FXR2,PAAF1,IPCEF1,PSMC4,PSMC3,DISC1,TMEM31,TRIM27,PSMC5,LURAP1,TNIK,DES,PARL,PSMD6,ADRM1,PSMD4,USP14,PSMD1,PSMD3,PSMD14,PSMD7,PSMD10,CCDC92 |
| 3.535e-04 | -7.95 | AANAT (aralkylamine N-acetyltransferase) | protein interactions | 15 | 15 | 11 | 19454 | 5460 |
UBB,EIF4E3,TOP1,YWHAZ,NACC2,KRTAP8-1,F2,BHLHE40,GRB10,MDFI,CIDEB |
| 3.535e-04 | -7.95 | GSTM5 (glutathione S-transferase mu 5) | protein interactions | 2949 | 15 | 11 | 19454 | 5460 |
GSTM4,SAR1B,GSTM5,CDC42,ERLIN2,BORCS6,PPP1CC,GSTM3,ARFGAP1,AGPAT1,GSTM2 |
| 3.535e-04 | -7.95 | SLC14A2 (solute carrier family 14 member 2) | protein interactions | 8170 | 15 | 11 | 19454 | 5460 |
PLN,CMTM7,MLF1,VAMP5,EHHADH,PLP2,SEC22A,TNF,MDM2,TMEM97,LRP10 |
| 3.540e-04 | -7.95 | Interferon_reg_fact_DNA-bd_dom | interpro domains | IPR001346 | 9 | 8 | 18521 | 5414 |
IRF4,IRF8,IRF9,IRF2,IRF3,IRF7,IRF1,IRF6 |
| 3.540e-04 | -7.95 | Interferon_reg_fac_CS | interpro domains | IPR019817 | 9 | 8 | 18521 | 5414 |
IRF4,IRF8,IRF9,IRF2,IRF3,IRF7,IRF1,IRF6 |
| 3.545e-04 | -7.94 | soft_tissue-smooth_muscle-leiomyosarcoma | COSMIC cancer mutations | soft_tissue-smooth_muscle-leiomyosarcoma | 42 | 23 | 16828 | 4835 |
HRAS,EWSR1,SF3B1,NFE2L2,STK11,SS18,AKT1,CTNNB1,RB1,CDH11,EZH2,PIK3CA,IDH1,KRAS,CDKN2C,ETV6,JAK2,FBXW7,MET,KIT,TP53,PTEN,TERT |
| 3.545e-04 | -7.94 | leiomyosarcoma | COSMIC cancer mutations | leiomyosarcoma | 42 | 23 | 16828 | 4835 |
IDH1,HRAS,KRAS,NFE2L2,SF3B1,EWSR1,SS18,STK11,FBXW7,JAK2,ETV6,CDKN2C,AKT1,TP53,RB1,MET,KIT,CTNNB1,EZH2,CDH11,PTEN,TERT,PIK3CA |
| 3.546e-04 | -7.94 | PRKCSH (PRKCSH beta subunit of glucosidase II) | protein interactions | 5589 | 219 | 85 | 19454 | 5460 |
ATP5IF1,PGK1,PMAIP1,AKAP1,DNAJC3,DDX39B,SOD1,BAP1,PEBP1,UPF3B,TMEM106B,HCFC2,PXMP2,RGS2,HSPA5,CMAS,GPC1,YTHDF1,SMC4,EDEM3,CFTR,UBE2M,DCTN4,ARMCX3,GRM2,HSP90B1,GANAB,RMDN3,SEC61B,UQCRC2,VIRMA,LDHA,MATR3,RANBP6,FBXO7,DRAP1,CUL3,HSP90AA1,UBE2H,CALU,ARHGAP19,BRCA1,DNAJC10,ATG3,INO80C,EWSR1,BCL7B,PDRG1,MCM6,ANP32B,TRIM26,ERLEC1,G3BP1,KPNA2,DNAJC30,ACTR1A,H2AX,TUBA1A,NUP153,VDR,ANP32A,TP53,ARFGEF1,PLD3,CYB5B,PLAAT3,HSPA13,EZH2,CHMP4C,CYB5A,ARL4D,CD274,COX4I1,PLGRKT,DNAJB9,SUMO2,KCTD10,PPIB,SYNJ2BP,DPP4,CMSS1,CALR,PGAM1,USP15,AGR2 |
| 3.556e-04 | -7.94 | RFC1 (replication factor C subunit 1) | protein interactions | 5981 | 216 | 84 | 19454 | 5460 |
RFC2,MSH6,SSRP1,RFC3,H3C1,EMC2,PCNA,FGF3,RPL31,SSBP3,SKA3,CBX3,EZH2,AURKAIP1,SOX2,CDK4,E2F4,TP53,ZNF263,RAF1,WIF1,SURF6,POLE3,TOP1,FZR1,RPS16,RB1,H2AZ1,BRD3,LHX2,H2AC4,SNRNP70,DDRGK1,WWP2,IFI16,LAMP2,POLA2,NUCKS1,SMC4,FBXW7,NF2,SQSTM1,NUP50,RNF113A,THBS3,HSPA8,XRCC5,NBN,POLD2,SIRT7,RFC4,BAP1,RPA3,PRIM2,CSNK1A1,HECTD1,MACROH2A2,GRM2,RPA2,LMNA,CCNA2,ZSCAN1,TPT1,CCND1,APEX1,MAD2L2,VIRMA,SNRNP40,TRIM29,TCEAL1,FGFBP1,PRKRA,CSNK2B,ZNF330,PSPC1,CCNF,UBE2H,BRCA1,RACGAP1,RFC5,BTF3,ZNF668,VAMP5,MYC |
| 3.556e-04 | -7.94 | MAGED2 (MAGE family member D2) | protein interactions | 10916 | 216 | 84 | 19454 | 5460 |
ARMC6,TUBB,ESR2,VIRMA,UBB,CTNNA1,DLST,KTI12,LMBR1L,CCNF,PTEN,GSK3A,TXNIP,PSMD14,UBE2H,ZBTB38,HSP90AA1,CUL3,CSK,MYC,STAU1,FBXW7,NPM3,UFL1,HSPA5,PML,BAP1,RPA3,RNF113A,HSPA8,METTL14,RPA2,HEXIM1,TPT1,TOMM22,EID2,GABRA1,FZR1,HSP90AB1,DUOXA2,EGLN3,DIRAS3,MDM2,ARL10,COQ8A,TES,SNRNP70,EID1,TUBG1,HAX1,EMC4,WWP2,IFI16,DDRGK1,TPM3,MAP3K14,XPO1,COPS5,CDK20,G3BP1,CHCHD2,RIGI,MEPCE,TCEA2,TRIM11,HAPSTR1,CHMP4C,TUBB4B,EZH2,MOB3C,CHRM3,TP53,E2F4,B3GNT2,KBTBD4,FBP1,RAF1,TUBA1A,NCSTN,MGARP,AURKAIP1,LBR,SOX2,EEF1A1 |
| 3.570e-04 | -7.94 | FIP1L1 (factor interacting with PAPOLA and CPSF1) | protein interactions | 81608 | 210 | 82 | 19454 | 5460 |
PRMT2,MIR34B,CPSF4,ATG16L1,DYRK2,MFAP1,NUFIP2,RPA2,TOX4,P4HA2,MIRLET7I,EP300,RPA3,SNRPA,BAP1,MIR205,PML,UFL1,HMGB1,STAU1,RUNX1,ARHGAP21,PPP1CC,CPSF2,ZMYND19,MYC,PAPOLA,CUL3,PRMT6,RIT1,UBE2H,SPOP,SF3B4,MIRLET7B,SGTA,CPSF1,PSPC1,CTTN,CSTF3,PPP1R10,SRPK2,ERH,NUP153,KIF2A,CSTF2T,RAF1,TAF2,DDX42,EZH2,CHMP4C,PDHA1,FAM76B,MIR9-3,SNIP1,MEPCE,MIR16-2,KRAS,FARSA,ASF1A,CPEB1,PPIL4,XPO1,YWHAG,COPS5,CSNK2A1,HNRNPA1,DDRGK1,WWP2,MED4,MIR221,BRD3,MIR34A,SKIC8,DDX23,CRTAP,SNRNP70,TIAM1,WDR82,CAMLG,CDK9,MIRLET7G,TOP1 |
| 3.573e-04 | -7.94 | STMN4 (stathmin 4) | protein interactions | 81551 | 33 | 19 | 19454 | 5460 |
NUFIP2,TRAPPC4,TRAPPC14,TRAPPC2L,SEC22A,AGTRAP,SELENOK,MARCHF5,SNAPC5,TRAPPC6B,VTA1,GCA,SPPL3,CHMP5,TRAPPC3,TRAPPC10,STX8,TRAPPC1,TRAF3IP3 |
| 3.573e-04 | -7.94 | TMEM35A (transmembrane protein 35A) | protein interactions | 59353 | 33 | 19 | 19454 | 5460 |
TMEM229B,TMEM243,COX20,RUSF1,VAMP3,ORMDL1,THBD,TRIM63,ADIPOQ,VAMP1,GOSR2,BET1,RPL7A,EHHADH,CYB5B,TMEM106C,TMEM42,FXYD6,CTSA |
| 3.573e-04 | -7.94 | PIGP (phosphatidylinositol glycan anchor biosynthesis class P) | protein interactions | 51227 | 33 | 19 | 19454 | 5460 |
SNRNP70,PIGA,PCMTD2,SCAMP5,FIS1,TMEM19,PYCARD,PLP2,UBIAD1,TMEM107,DDX39A,DPM2,APEX1,TMEM168,COX4I1,PLP1,PTPN1,TMEM229B,CLK1 |
| 3.576e-04 | -7.94 | TIAM1 (TIAM Rac1 associated GEF 1) | protein interactions | 7074 | 201 | 79 | 19454 | 5460 |
SGTA,ALB,AP2M1,DLG4,SRC,KBTBD6,VIRMA,PPP1R10,RHOJ,PRKCE,DNAJC5,MAP3K21,SMARCE1,FAM110B,SFN,TMED4,CREBBP,MYC,RAB2A,SERPINH1,EPHA2,FBXW11,YWHAZ,RHOB,SNTA1,PRKCB,FAM53C,ATP5IF1,RTKN,LIN7C,RHOU,DNAAF9,ABCC5,STX7,CREBZF,CFTR,RAB6A,CDC42,SIPA1L1,RPL27A,INPP5E,CSNK1A1,AGAP1,PRKCA,CRYAB,GJA1,EIF4E2,HRAS,RAB35,CTDSPL2,CAV1,DIRAS3,TOP1,ARF6,KCTD3,YWHAG,YWHAH,YWHAB,CAMSAP2,NEUROD2,TIAM1,SNRNP70,RHOG,TESK2,EFNB1,DLG1,FLOT1,SRSF12,KRAS,ATP1A2,CAMK2G,CHCHD2,KIF1C,CSNK1E,CASK,NME1,KRIT1,RPN1,DDX42 |
| 3.576e-04 | -7.94 | EXOC3 (exocyst complex component 3) | protein interactions | 11336 | 139 | 58 | 19454 | 5460 |
SDC2,KLC2,SCLT1,ATG16L1,CDC42,FBXW7,STX7,CXCR4,RHOU,RAB5A,EP300,RAB9A,LAMTOR1,RHOB,CCDC22,EXOC8,RALB,TRIM32,MYC,RAB11A,GPR17,EXOC5,DNAJC5,RALA,BUB3,FBXO22,RHOJ,ESR2,SCHIP1,VAMP2,RAB4A,KHDC4,DLG3,IL1R2,TULP3,KIF2A,KRAS,FLOT1,IMMP2L,TMED1,HAPSTR1,DHX9,RHOG,H2AC4,EXOC2,KXD1,PRPF19,LAMP3,INSYN1,DDRGK1,EXOC1,STX6,MACROD1,CAV1,METAP1,HRAS,RAB35,GJA1 |
| 3.576e-04 | -7.94 | CDCA5 (cell division cycle associated 5) | protein interactions | 113130 | 139 | 58 | 19454 | 5460 |
HSPD1,PABPC1,RUVBL2,EWSR1,ACTR1B,HNRNPF,H3C1,RUVBL1,THRAP3,TICAM1,VPS16,POLDIP3,PCGF6,RFC2,RAD21,NAA16,EEF1A1,CD2BP2,NHERF1,MGME1,SPTAN1,NCBP2,NAA11,DHX15,CD99L2,SLAIN2,CETN2,RBM17,RPAIN,SF3B1,HSPA8,GPHN,KDM1A,EEF1G,STK38,UNC45A,WDR77,ACTL6A,SPTBN1,GTF3C4,LMNA,CDK1,ZER1,EIF2AK2,TUBA1B,PRMT5,EIF4A2,TMOD3,SPINDOC,RBBP4,TAB1,STK38L,MYC,HNRNPC,SMARCE1,PRPF31,SPOP,HSP90AA1 |
| 3.576e-04 | -7.94 | ARMC6 (armadillo repeat containing 6) | protein interactions | 93436 | 139 | 58 | 19454 | 5460 |
MAP1LC3B,CCT5,TMEM126A,B3GNT2,PLD3,AQP3,SLC2A8,CCT8,SLC20A2,PGAP4,CD80,EPHA4,COPS5,XPO1,PFDN5,MICB,SLC20A1,HSPB1,PPM1B,MUL1,TES,MAGED2,EEF1AKMT3,AIFM1,CCT7,EGLN3,TCP1,PCSK9,SPPL3,CDC42,SLC35E1,DAAM1,SLC16A10,ARCN1,ACAA2,GALNT1,EP300,LCN1,ATP5MK,RPA3,CLU,MFSD3,NPTN,CNNM4,PYCR1,CUL3,FOXA3,GPR17,SLC7A11,XPOT,FBXW11,CCT2,SEC61B,STX10,GGT7,TUBA1B,CCNF,TUBB |
| 3.577e-04 | -7.94 | ATP6V1F (ATPase H+ transporting V1 subunit F) | protein interactions | 9296 | 116 | 50 | 19454 | 5460 |
IGF1R,TRIM11,FKBP8,KRAS,NEDD8,UBE2V1,MAP1LC3B,DNAJC25,ZRANB2,PTRH2,UBE2B,RAC2,ATP6V1A,CORO1C,IGBP1,TLDC2,PTPN1,COX14,HNRNPL,ROGDI,VPS26A,TMEM199,MOV10,STYK1,ATP6V1D,ESYT1,RHOG,UBE2D1,RAB9A,TMEM185A,ATP6V1G1,FBXW7,ATP6V1G2,UCHL3,SRSF2,ST7,CNPY3,OTULINL,MPV17,ATP6V1C1,PICALM,PTP4A2,EIF2AK2,SRXN1,VDAC2,ATP6AP2,SEC63,TXN,CUL3,RIT1 |
| 3.577e-04 | -7.94 | RDH11 (retinol dehydrogenase 11) | protein interactions | 51109 | 116 | 50 | 19454 | 5460 |
HSCB,TSPAN5,RPA3,HSPA8,RAB5A,EP300,RTN4,RPA2,PICALM,PRKCA,GINM1,PGRMC1,CA12,TMEM106A,OTULINL,CFTR,CDK7,PYGM,RHOJ,SH3BGRL,LMBR1L,DPEP1,SEC61B,RHOB,CABCOCO1,MYC,GGH,SRPRB,PSEN1,GOLGA7,RDH11,ATP5PF,TMEM268,BLOC1S2,SEMG2,TMEM31,SFTPC,SELENOF,MOB3C,RAF1,DCAKD,CCDC47,ISG15,LGR4,HNRNPL,WIF1,COMT,ESYT1,CFC1,ADIPOR2 |
| 3.577e-04 | -7.94 | NT5DC2 (5'-nucleotidase domain containing 2) | protein interactions | 64943 | 116 | 50 | 19454 | 5460 |
METTL15,TULP3,MRPL11,PDHA1,HINT2,COX8A,HSPD1,FASTKD5,TFG,IMMP2L,TOLLIP,ETFRF1,POU5F1,TSNAX,RHOG,GATD3,SSBP1,RCHY1,EGLN3,SURF6,RHOH,CDC42,HECTD1,MTRES1,RPA2,HSPB2,GFM1,RPA3,RHOU,EXD2,POLDIP2,UFL1,HSCB,NME4,STAU1,TUFM,FMC1,AUH,MTG2,EMILIN1,CUL3,PMPCA,UBE2H,TRIM27,TACO1,MTG1,CMTR1,ESR2,MAD2L2,RHOJ |
| 3.577e-04 | -7.94 | TRIOBP (TRIO and F-actin binding protein) | protein interactions | 11078 | 116 | 50 | 19454 | 5460 |
HAUS2,DYRK2,FGFR1,VAPB,CFTR,BORCS6,CDKN1A,PPP1CB,WDR77,ATG16L1,PACSIN3,MCMBP,STAU1,FXR2,RHOU,CORO6,VMP1,NRP1,RHOB,FBXW11,FYTTD1,PPP1CC,DNAJC5,SKAP2,ESR2,DYRK1A,THAP8,POLR2F,EIF3K,SRXN1,PSMC3,RND3,CAPZA2,VPS33A,KIF2A,SOX2,JPH4,ERLEC1,NTRK2,HECTD3,PPP1R12A,RHOG,INSYN1,DPP4,KXD1,CGAS,RHOH,HNRNPL,ALDH1A3,SYNCRIP |
| 3.577e-04 | -7.94 | EHD4 (EH domain containing 4) | protein interactions | 30844 | 116 | 50 | 19454 | 5460 |
LAMTOR1,EXOC8,NTRK3,RAB11A,OLFM3,MYC,BTF3,RHOJ,TENT5C,UQCRC2,CTBP1,RPA2,HECTD1,EHD3,RBMS2,GTF3C4,CDC42,EHD1,STX7,EXD2,ACTMAP,RHOU,RPA3,EP300,RAB5A,HSPA8,H2AC4,DNAJC7,FAM20C,FAM174A,CLPX,ATG9A,NT5C2,RHOH,AASDHPPT,SUMO2,CGAS,CDC5L,WIF1,FBXO32,EEF1AKMT3,EZH2,MTMR2,SOX2,TGFBR2,ETFA,KRAS,TRIM11,BAG2,TMX3 |
| 3.577e-04 | -7.94 | GNB4 (G protein subunit beta 4) | protein interactions | 59345 | 116 | 50 | 19454 | 5460 |
RHOH,RAC2,DFFA,KCND2,RHOG,GNG2,HDAC6,GNG11,XPO1,H3C1,KCTD17,VDAC1,ABCE1,TSPAN17,GNG5,RGS6,GNA11,GNAQ,GNAI3,TFCP2,SKA3,GNG3,GNG10,GNG13,GNAI2,CEP97,GNB1,RHOJ,SLC25A4,PTEN,VDAC2,GNG12,CYB5R3,NTRK3,NR2E1,RHOB,USP14,CSK,MYC,ADRB2,GNGT2,NMRAL1,TMEM185A,TMEM106B,PDCL,PTP4A2,GNG7,RND2,CDC42,CFTR |
| 3.578e-04 | -7.94 | HSPB6 (heat shock protein family B (small) member 6) | protein interactions | 126393 | 13 | 10 | 19454 | 5460 |
CRYAB,PNMA2,BECN1,ATG4A,HSPB1,MAP1B,FBXO11,YWHAG,HSPB8,BAG3 |
| 3.578e-04 | -7.94 | SPINK5 (serine peptidase inhibitor Kazal type 5) | protein interactions | 11005 | 13 | 10 | 19454 | 5460 |
TFG,CSGALNACT1,PRSS1,ZDHHC15,CCR1,DCAF4,ISCA2,SOX2,FOS,FSTL1 |
| 3.594e-04 | -7.93 | positive regulation of amyloid precursor protein catabolic process | biological process | GO:1902993 | 25 | 16 | 18204 | 5365 |
TNF,SPON1,CLU,EFNA3,IFNG,ROCK2,MIR206,EPHA4,GSK3A,CSNK1E,SP1,LRRTM3,CHRNA7,PICALM,IFNGR1,AGER |
| 3.613e-04 | -7.93 | MTDH (metadherin) | protein interactions | 92140 | 484 | 170 | 19454 | 5460 |
CSNK2A1,EMC4,FAM20C,EDEM1,SLC25A46,CYP4V2,RPL10A,SNRNP70,RAC2,PWP2,HSD17B11,CD274,PTPN1,RBM42,TMPO,DKC1,SELENOI,MDM2,SNN,TOP1,FZR1,DNAJC1,RPS16,BCS1L,RPL15,OR8G5,DUSP1,MRPL11,CCL20,TBK1,SRP72,RNF8,TOPORS,CAPN2,RBM34,DISC1,DNAJC2,DHX9,RPL3,TCOF1,RIGI,FKBP8,EGR1,RAB3B,USP14,TUFM,PTHLH,KCNQ5,IL2RB,RPL7A,RPF2,UBE2H,AP2A1,GRID1,RC3H2,TLR9,NR2E1,EIF2S2,METAP2,ENO1,PSPC1,SEC63,BCCIP,VIRMA,CPT2,CTSB,CDK7,ST7,CDC42,GTF3C4,GABRA1,KCNH1,RPLP0,MAP3K12,SSR1,RPA2,LMNA,RAB9A,DERL1,SQSTM1,MTDH,MNS1,EXOSC4,PML,MME,RPA3,BRIX1,FBXW7,RPL4,DDRGK1,MAP3K14,HNRNPA1,NDC80,RPL6,WWP2,DDX50,IFI16,ANKRD50,DRG1,RHOG,WDR12,IKBKB,HP1BP3,PLEKHO2,NEO1,PHB1,MRTO4,SPRED2,TMEM237,RPL7,EIF2S1,ISG15,JUN,DNAJC25,OTUD6B,RANBP1,B3GNT2,RAF1,RPL18,CYB5B,ITGB5,PPFIA2,PTRH2,RPN1,STIM1,RPS24,TRIM21,PRPSAP1,HNRNPA2B1,TMT1A,SSRP1,SIAE,MCM6,ZBTB16,PCCB,RAB11A,CUL3,CREBBP,MYC,FTSJ3,SEC61B,AP2M1,IRF2,RPL19,SPCS1,SNRNP40,SSH3,CYP27A1,STXBP1,ESAM,SEC62,RND2,OTULINL,DMTF1,SYK,ACTL6A,LARP4B,SDC2,RAB5A,EP300,G3BP2,STX7,PXMP2,EEF1G,STAU1,HNRNPA0,FXR2,PSENEN,CYFIP2,UFL1 |
| 3.626e-04 | -7.92 | PTMS (parathymosin) | protein interactions | 5763 | 77 | 36 | 19454 | 5460 |
AKT3,CALR,CREBBP,PDIA3,PGAM1,PPIB,TPM3,SMAD2,YWHAB,NKX3-1,DSTN,TRIM24,DCK,MIF,SUMO2,ANP32A,PRDX3,SCHIP1,ADSS2,EZH2,RPRD1B,CBX3,DDX39B,HSPD1,SOD1,PEBP1,ATP5IF1,PGK1,EP300,NUBP2,IDH1,RBBP7,HSPE1,OXCT1,RIGI,ANP32B |
| 3.626e-04 | -7.92 | PTPN5 (protein tyrosine phosphatase non-receptor type 5) | protein interactions | 84867 | 77 | 36 | 19454 | 5460 |
HACD3,DLG4,UBP1,SEC61A1,ATP5F1B,VTI1B,REEP4,CXCL9,ATP5PD,TOMM70,MARCHF5,CDKN3,PTPN5,CYB561D2,SEC61A2,CCNQ,ATP5MC1,MAPKAPK3,ENTPD3,RTN4,CERS2,MAPK1IP1L,MEF2A,RPS27A,ZBTB5,DCAKD,ATP5PB,MTCH2,PGRMC1,DDX39A,FAF2,VAPB,NFKBIL1,ATP5PO,RPN1,GHITM |
| 3.635e-04 | -7.92 | coated vesicle | cellular component | GO:0030135 | 319 | 121 | 19108 | 5553 |
ATP6V1D,FURIN,SGIP1,CIDEB,SURF4,SNX3,ARCN1,TMED5,CD3G,ATP6V1G2,GOSR2,ATP6V0B,SFTPA1,CNIH4,SNX18,TF,AP1M1,AP2A1,RNASEK,TMED7,ADRB2,TEX261,SH3BP4,DNAJC5,SFTPD,PHETA2,SCYL2,RAB5A,GRIA1,AP1G2,AP2S1,STX5,VWF,HSPD1,NECAP1,TMED4,VPS33A,DIPK2A,SFTPC,STX6,CD59,RAB14,SLC32A1,TMED3,CD9,TMED9,TMED1,FOLR1,PICALM,SYNRG,YIF1A,MLC1,OCRL,USE1,REEP6,TBC1D5,ATP6V1C1,CFTR,TMEM199,AFTPH,HAX1,RAB8B,SLC30A5,CLVS1,HBEGF,VAMP8,FCHO2,ATP6AP2,SYT2,CLBA1,SLC2A8,VTI1B,CLRN1,RAB35,TFRC,SNAP91,SPG21,VAMP2,RAB13,MYO6,NECAP2,KLHL12,CNIH1,LMAN1,HSPA8,KDELR2,FCGR1A,PCSK9,AP2M1,SERPINA1,GAD2,RAB3A,YIPF5,CTSC,LMBRD1,RGS19,CTLA4,VPS16,CLVS2,SEC23A,SAR1B,FZD4,STX17,ASTN1,SEC22B,ATP6V1A,VPS18,B2M,COPZ2,AP1S2,LDLR,NCALD,DVL2,SEC13,VAMP7,CD4,VAMP3,DNM2,RAB27A,KDELR1,COPE |
| 3.649e-04 | -7.92 | ACTL6A (actin like 6A) | protein interactions | 86 | 274 | 103 | 19454 | 5460 |
VAMP5,MORF4L1,AR,RUNX1,UBE2H,METAP2,CCNF,PTEN,ING2,CSNK2B,RAB14,DEK,SF3A1,ATG16L1,ELP3,RPA2,RPRD1B,PDCL,BANF1,BAP1,SNAPC1,MTDH,FBXW7,CXXC1,SS18,MBD3,MOV10,BRD3,H2AZ1,THOC1,PRNP,TOP1,CAND1,SPPL3,CDK9,TP53,ZNHIT1,SMAD1,ING1,DMAP1,RNF8,SNIP1,TFPT,HINT1,MRPL22,CUL3,HNRNPC,MYC,SMARCE1,ATG3,CCT2,CYB5R3,VPS72,DLST,PRMT5,FBXO22,TRIM29,RBBP4,ACTB,ESR2,APEX1,CBX5,ACTL6A,ETF1,SMARCD3,EP300,DDIT3,HSPA8,SAP18,WWP2,INO80E,BAZ1B,HMGA1,PRPF19,CTNNB1,DDRGK1,BCL7C,MED4,SIN3A,BRD9,TCP1,RAB1B,CCT7,MAX,FEN1,SAP30,SOX2,CHMP4C,H2BC1,MOB3C,SMARCB1,MTA2,ZRANB2,TOP2B,BCL7B,MRPS11,TRIM11,RUVBL2,INO80C,EWSR1,RUVBL1,RBBP7,SSRP1 |
| 3.653e-04 | -7.91 | RNF213 (ring finger protein 213) | protein interactions | 57674 | 142 | 59 | 19454 | 5460 |
AR,GPR17,H1-1,ATP1A1,FIS1,COP1,TRIM23,RPS12,SNRPD2,TRIM27,CCNF,SCN2B,VIRMA,ESR2,GNB1,UBE2L3,COPE,HCST,PPP1CB,POLR1D,UBE2M,RPA2,LMNA,SDC2,MTDH,PML,CD40,RPA3,PIP4P1,FBXW7,UBE2K,UBE2D3,NPTN,DLK2,LAMP3,FAM174A,IFI16,USP15,PPP3CA,PLAC9,UBE2N,PTPN1,SRPRA,OSBP,SUMO2,MRPL50,LYAR,HNRNPL,MGARP,ISG15,RHOBTB1,STK16,CHMP4C,SIGLECL1,IGF1R,EFNB1,OSTM1,HS2ST1,HNRNPK |
| 3.657e-04 | -7.91 | IRF | pfam domains | PF00605 | 9 | 8 | 17795 | 5224 |
IRF3,IRF4,IRF8,IRF1,IRF2,IRF6,IRF7,IRF9 |
| 3.658e-04 | -7.91 | TLK2 (tousled like kinase 2) | protein interactions | 11011 | 88 | 40 | 19454 | 5460 |
RBBP7,H3C1,IRF7,SCML1,ASF1A,STAU1,RPS27A,GSKIP,PAX6,HIRA,PML,PCNA,DDIT3,CBX3,DMAP1,RPA2,CDAN1,SPRR1B,TULP3,SNRNP40,DYNLL1,LRIF1,APEX1,ESR2,FABP5,AIFM1,FEZ1,REP15,UBN1,ABHD14B,CALML5,UBE2I,CSTA,YWHAZ,STK24,MYC,IRF4,XPO1,MCM3,CEP70 |
| 3.703e-04 | -7.90 | proteolysis | biological process | GO:0006508 | 1177 | 399 | 18204 | 5365 |
RNF11,OTUD7B,ADAMTS1,FBXL4,GZMK,DCAF11,TPSG1,UCHL3,TMUB2,DPEP1,KLHL15,METAP1,ADAMTS10,ZFAND2A,NEDD8,FCN2,RLIM,ISG15,RNF8,KLK3,FAM8A1,VPS4B,RNF167,PRSS1,PRSS23,USP13,FEM1B,SDF2L1,HGS,RNF126,COPS5,EDEM1,USP14,PGPEP1,CTSB,ANAPC11,PRPF19,OS9,PSMB1,TOPORS,UBXN10,ADAMTS20,DNAJB9,PRCP,IL1R2,NDFIP1,CBL,OLR1,ANAPC4,ACTMAP,RCHY1,FBXO11,IFT172,ZER1,FZR1,FAF2,CDC20,SPON1,WWP2,PREPL,CDC16,PMPCA,USP15,UBE2A,FBXO8,RNF34,ATP6AP2,HERC3,PCSK2,REN,CMA1,ERLIN1,RNF7,STAMBPL1,USP5,KCTD17,ANAPC15,CELA3B,FURIN,USP8,RC3H2,F9,IDE,UBE2I,FXN,MTM1,PSEN1,TRIM26,ZMPSTE24,PSMB10,SPOP,HSPA5,HTRA2,KLHL3,WWP1,FBXO31,ERLEC1,SENP8,PSMA2,APPBP2,MMP21,TMUB1,GID4,HECW1,RNF5,PSMD3,PLG,FEM1A,DNAJC10,STUB1,MME,KLK9,MBL2,PSMD4,NSFL1C,H2BC1,SH3BGRL,MINDY3,KLK6,VPS28,FBXW11,SPCS1,CASP4,TNFAIP1,USP16,LCN1,HSP90B1,EDEM2,F2,OTUD6A,CAPN1,FBXO3,RNF133,PSMD14,CTSD,RNF144B,RAD23B,CNDP2,FBXL14,ANAPC16,UBE2D3,VPS4A,MDM2,CDC26,AGA,SPPL3,CTSC,SPCS3,VCPIP1,PSMB5,SVBP,HUWE1,CRBN,ENC1,CLCA1,CTRB2,SEC11A,DDIT3,FBXL7,TRIP4,PSENEN,VASH1,CHMP1B,NCSTN,FBXO22,PSMB9,EDEM3,FAF1,PCYOX1L,HMCES,UBE2H,METAP2,HINT1,CUL2,RNF139,SIAH1,RBCK1,MYRF,CHMP4C,DESI1,SGTA,JOSD1,F10,CSNK1A1,COP1,SPCS2,RNF20,HECTD1,UFD1,KLHL22,CHMP5,PRKCQ,RNF187,BAK1,GID8,CTSK,TNFAIP3,CTNNB1,CYFIP2,KLK5,UBE2W,PPP1R11,FEM1C,APH1A,RNF103,ARMC8,CALR,PSMA4,PSMD6,PSMA5,PSMD12,WDR77,FBXO9,RPS27A,UBA52,RNF128,ADAM21,UBXN6,FKRP,SELENOS,DDI1,UBE2G2,HERC4,SIAH2,AKT1,BMP1,PSMA3,SCPEP1,GSK3A,PSMD7,SYVN1,PARL,RGMA,BAD,DERL1,TSG101,FBXL19,MATCAP1,PCSK9,USP3,USP46,SKP1,PSMC3,PLAA,ATG4C,DESI2,UBE2N,UBE2D1,CPE,TOLLIP,HTRA1,XBP1,SPSB1,PSMB3,SEC61B,TOM1L1,USP38,USP2,STAMBP,PSMB7,CHMP1A,UBB,MMP9,STOML2,IMMP2L,MMP14,UBE3A,DPP10,RNF14,ERLIN2,UBE2K,ADGB,KLHL25,PELI1,PSMA6,PPP2CB,RNF122,HECTD3,OTUD6B,CHMP2B,BAP1,ASRGL1,PMAIP1,CASP12,TP53INP2,PSMB6,UQCRC2,IFI27,CHMP2A,ANAPC2,HM13,ENPEP,PREP,CPNE1,MMP20,DNAJC3,DNAJB2,JKAMP,ECRG4,PSMB2,UBE2S,SMURF1,UBA3,UBE2B,RHOBTB3,MAEA,PSMB11,TRIM32,UBE2L3,BIRC2,PSMC4,KBTBD6,ELOC,UBAP1,APEH,VSIR,ATG4A,PRSS8,KCTD10,HDAC6,FBXW7,LAP3,PSMA1,NLRP1,BFAR,PSMC1,OTULIN,ANAPC13,SCG5,UBL4A,DERL2,UBXN2B,DISC1,PRSS12,PSMC5,PRSS37,CLPX,FBXW4,RMND5B,PML,RNF10,YIPF5,DPP4,RNF40,RNF26,THBD,DPEP3,NAE1,CCNF,MYLIP,CACUL1,TRIM45,RHBDL3,USP30,ZFAND2B,SENP5,ADRM1,RNF146,DTL,F7,SPOPL,FBXL3,RNF121,CDC23,BACE1,ANKIB1,PSEN2,RNF41,SQSTM1,TRIM21,SRGN,XPNPEP1,MMP28,PSMB4,DAG1,CTSA,SPSB3,CCAR1,RNF115,FBXO7,NFE2L2,RCE1,AREL1,CAPN2,PGK1,IFI16,FBXO44,KLF1,CUL3,CCDC47,ZNRF1,RNF148,PGA4,PIGK,MAN1A2,TMEM208,TRIM3,PSMD1,SLC30A5 |
| 3.708e-04 | -7.90 | OXCT1 (3-oxoacid CoA-transferase 1) | protein interactions | 5019 | 119 | 51 | 19454 | 5460 |
PEDS1,RHOG,HSPB1,AIFM1,SDHAF2,GATD3,PRSS35,LYPLA1,CMPK1,SOX2,NME1,NDUFS3,CBX3,PSME1,TCOF1,HSPD1,AGA,IDH1,HINT1,TF,RBBP7,PSEN1,PMPCA,TXNRD2,PTPN11,FMC1,AUH,MYC,MTPN,CHCHD4,MDH1,OAT,ENO2,CTTN,PTPMT1,SUCLG2,MYG1,STXBP1,VAPB,ADSS2,PAK5,MTRES1,PML,SOD1,GFM1,PRDX6,HSPA8,PGK1,OXCT1,TMEM177,GRPEL1 |
| 3.711e-04 | -7.90 | Toll Like Receptor TLR1:TLR2 Cascade | REACTOME pathways | R-HSA-168179 | 95 | 46 | 10285 | 3229 |
CD36,SKP1,TLR1,MAP2K3,NFKBIA,MEF2C,MAP2K1,UBA52,TLR4,PELI3,UBB,PPP2R1A,PELI1,CREB1,ELK1,FOS,TAB1,TLR6,DUSP6,S100B,NFKB1,IRAK4,JUN,AGER,LY96,FBXW11,IKBKB,TLR2,TRAF6,HMGB1,DUSP3,CD14,MYD88,RPS27A,NFKBIB,ATF1,TAB2,MAP2K6,MAPKAPK3,TIRAP,MAPK10,UBE2N,PPP2CB,UBE2V1,MEF2A,DHX9 |
| 3.711e-04 | -7.90 | Toll Like Receptor TLR6:TLR2 Cascade | REACTOME pathways | R-HSA-168188 | 95 | 46 | 10285 | 3229 |
RPS27A,IKBKB,TLR2,DUSP3,TRAF6,HMGB1,CD14,MYD88,PPP2CB,UBE2V1,MEF2A,DHX9,ATF1,TAB2,NFKBIB,MAPKAPK3,MAP2K6,TIRAP,MAPK10,UBE2N,MEF2C,MAP2K1,UBA52,TLR4,PPP2R1A,PELI1,UBB,PELI3,CD36,SKP1,MAP2K3,TLR1,NFKBIA,IRAK4,NFKB1,LY96,AGER,JUN,FBXW11,ELK1,CREB1,TAB1,FOS,TLR6,S100B,DUSP6 |
| 3.711e-04 | -7.90 | MyD88:Mal cascade initiated on plasma membrane | REACTOME pathways | R-HSA-166058 | 95 | 46 | 10285 | 3229 |
ELK1,ATF1,TAB2,NFKBIB,CREB1,MAPKAPK3,MAP2K6,TIRAP,TAB1,MAPK10,FOS,UBE2N,TLR6,DUSP6,S100B,IRAK4,NFKB1,PPP2CB,LY96,JUN,UBE2V1,AGER,MEF2A,FBXW11,DHX9,CD36,TLR2,IKBKB,DUSP3,TRAF6,SKP1,HMGB1,CD14,MAP2K3,TLR1,NFKBIA,MYD88,MEF2C,MAP2K1,RPS27A,UBA52,TLR4,PPP2R1A,PELI1,UBB,PELI3 |
| 3.711e-04 | -7.90 | Toll Like Receptor 2 (TLR2) Cascade | REACTOME pathways | R-HSA-181438 | 95 | 46 | 10285 | 3229 |
NFKB1,PPP2CB,IRAK4,UBE2V1,AGER,JUN,LY96,FBXW11,MEF2A,DHX9,CREB1,NFKBIB,TAB2,ATF1,ELK1,MAP2K6,MAPKAPK3,FOS,MAPK10,TAB1,TIRAP,S100B,DUSP6,TLR6,UBE2N,MEF2C,MAP2K1,TLR4,UBA52,RPS27A,UBB,PELI3,PELI1,PPP2R1A,CD36,IKBKB,TLR2,HMGB1,SKP1,TRAF6,DUSP3,TLR1,MAP2K3,CD14,MYD88,NFKBIA |
| 3.718e-04 | -7.90 | MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit) | protein interactions | 27430 | 102 | 45 | 19454 | 5460 |
UGDH,RPA3,GTF2I,HSCB,CAPN1,P3H1,RPA2,PIH1D1,HNRNPH3,CCNF,TRIM27,AP2M1,GMDS,TUBB,EIF4H,TXN,FERMT2,GFUS,MAT2A,BAG3,GALE,ARHGAP21,STK24,UBE2H,AP2A1,SEMG2,PDIA6,ERO1A,SEPHS1,FBXO25,TUBA1A,MOB3C,DFFA,XPO5,ARHGAP25,PRNP,SNX1,G6PD,MBD5,GAPDH,XPO1,ATG7,PPP3CA,DNAJC4,NAB2 |
| 3.718e-04 | -7.90 | INTS6 (integrator complex subunit 6) | protein interactions | 26512 | 102 | 45 | 19454 | 5460 |
PPP1CB,FAXC,PPP2R1A,CTDSP2,INTS6L,SUPT5H,POLR2G,POLR2C,POLR2D,ACACA,RPA2,ELOF1,RNF113A,RPA3,S100B,PML,SSRP1,RIGI,SEM1,ZNF592,KRAS,ANAPC15,PPP1CC,MOV10,ZNF687,CUL3,UQCR11,RIT1,ANKRD50,NAIF1,INTS10,POLR2F,INTS12,S100A6,KCNA2,EZH1,NABP1,POLR2L,PPP2CB,POLR2B,ESR2,CDC5L,STAT2,HNRNPL,TOP1 |
| 3.718e-04 | -7.90 | LRRK1 (leucine rich repeat kinase 1) | protein interactions | 79705 | 102 | 45 | 19454 | 5460 |
RAB29,INPPL1,SQSTM1,HSPA8,TIRAP,CDK1,CCL21,SH3GLB2,MTG1,VGLL4,FBXL14,CDC42EP3,STUB1,DAPK1,PPP5C,CUL3,PTPN11,BAG3,BRCA1,BLOC1S5,CCT2,HSP90AA1,PDCD4,CCT8,BAG2,SOS2,HNRNPK,PAK6,CCT5,TOP3B,CD2BP2,GNAZ,GPBP1L1,CLVS1,S100A8,TCP1,CPLX3,HSP90AB1,CWC15,CCT7,CACYBP,PPM1B,SHC1,FOXP1,LYZ |
| 3.743e-04 | -7.89 | LZTFL1 (leucine zipper transcription factor like 1) | protein interactions | 54585 | 48 | 25 | 19454 | 5460 |
HNRNPD,BBS5,LANCL2,NTAQ1,APEX1,BUB3,SC5D,PSMB1,PSPC1,SH3GLB2,TRIM68,RPA2,SDCBP,GTF2E2,EHHADH,RIGI,HNRNPDL,UNC45A,PSMA1,ROCK2,PHB2,LZTFL1,PICK1,TTC8,BAP1 |
| 3.743e-04 | -7.89 | MIEF1 (mitochondrial elongation factor 1) | protein interactions | 54471 | 48 | 25 | 19454 | 5460 |
CMTM6,PSMA1,AKAP1,ATP5PF,ABHD5,CDC42,AGTRAP,MTCH2,MIEF1,RAF1,VIRMA,APEX1,ARL10,OPTN,BCL2L1,YWHAB,FIS1,YWHAZ,SYP,MED21,MFN1,YWHAH,YWHAG,SFN,MARCHF5 |
| 3.745e-04 | -7.89 | CHMP3 (charged multivesicular body protein 3) | protein interactions | 51652 | 61 | 30 | 19454 | 5460 |
SMAD1,ARHGAP1,STAMBP,HSPA13,VAV2,CRABP2,CHMP1A,VIPAS39,CHMP4C,CHMP2B,MEPCE,VTA1,TFG,KRAS,CERS2,CHMP1B,FBXO7,BTF3,MYC,FGFR1OP2,RAB11A,VPS4A,SMAD4,ALDH1A3,TNPO3,ZBTB2,SMAD5,CHMP2A,CGAS,CHMP5 |
| 3.747e-04 | -7.89 | negative regulation of leukocyte apoptotic process | biological process | GO:2000107 | 56 | 29 | 18204 | 5365 |
CCL21,MIF,ORMDL3,LILRB1,BCL10,CXCL12,BCL6,PRKCQ,CCR5,CCL19,IL2,CCR7,MIRLET7B,TSC22D3,SELENOS,CCL5,IRF7,HCLS1,BCL2L1,FOXP1,ST6GAL1,IDO1,SLC39A10,PDCD1,RAG1,GPAM,ARG2,PTCRA,ST3GAL1 |
| 3.756e-04 | -7.89 | YIF1B (Yip1 interacting factor homolog B, membrane trafficking protein) | protein interactions | 90522 | 69 | 33 | 19454 | 5460 |
GPR35,RPA2,LXN,ATP5PB,CDK7,YIPF5,RER1,LYG2,RIGI,ATP5PF,RPA3,RAB1A,AKT2,YIF1A,DERL1,LPAR2,HSPA8,VIPR1,ESYT1,SPOP,SLC2A1,P2RY1,TNFSF13,ICAM2,AKT1,KDSR,CCR6,TNFSF18,B4GALT3,RAB1B,GPR37,S1PR4,SLC1A1 |
| 3.765e-04 | -7.88 | H2BC21 (H2B clustered histone 21) | protein interactions | 8349 | 658 | 224 | 19454 | 5460 |
HPF1,PPP1R10,SMURF1,ZNF518B,LIG3,TMA7,QSER1,MACROH2A1,MECP2,TMEM196,BICD2,CHRAC1,ANAPC4,PDCD4,SMARCA5,AKT1,SUB1,MORF4L1,KDM1A,STK38,OIP5,MARS1,HCFC2,BANF1,NBN,SMG5,RPRD1B,HEXIM1,DYRK2,RAG1,INTS6L,ING5,CAND1,SHPRH,VPS26C,GATAD1,POLB,MED27,H2AC4,NOS1AP,SMCHD1,KPNA1,USP15,COPS5,PPM1D,TPM3,NUP107,PSMA5,H3C1,MEPCE,MNAT1,H2BC14,MAP1B,CBX3,CHAMP1,PHC1,RNF8,TBC1D4,KBTBD4,TP53,H2AX,ZMYM4,ZMYM3,CBX5,LRIF1,POLR2B,PHF12,MIDEAS,SMU1,ZMYM2,ATG3,H1-10,PSMD14,H1-1,CREBBP,MYC,PRMT6,BTF3,DRAP1,UFL1,LYG2,RFC4,HIRA,SLU7,XRCC5,PCGF2,EP300,CTBP1,MEAF6,HMG20A,CCDC71,EED,WDR82,HEATR9,CBL,IFI16,BAZ1B,ZCCHC10,WWP2,DNTTIP1,STK4,H1-6,ROCK2,RUVBL1,CDCA7L,TOP2B,RUVBL2,H2BC1,SMARCB1,MTA2,APTX,NAA16,SUPT5H,MED9,H1-3,NUP37,SCML2,SFRP4,DEK,VIRMA,PELP1,CCNF,TRIM24,ZSWIM7,CDC73,MAPRE1,TPPP3,CDC16,ZNF687,PYCR2,RACGAP1,SGF29,NUCKS1,USP8,FBXW7,MBD3,BRIX1,PPM1G,SIRT7,PRKCB,TOX4,P3H1,LMNA,H2AC7,MACROH2A2,UBA52,CGAS,TOP1,CDK9,POLE3,MDM2,H2AZ1,CTDSPL2,H2AC14,HUWE1,VRK1,POLL,RNF20,FBXO25,H2AC6,MSH6,MDC1,RGS6,H2AJ,RBBP4,ERH,PRRC2A,RPL19,ZNF22,FAM91A1,PARP2,RSRC1,VPS72,AP2M1,MED10,BRCA1,LMNB1,CUL2,CUL3,RFC5,RNF40,SMARCE1,MCM3,MCM4,ATAD1,CCDC86,JADE1,CFDP1,NUP50,APOBEC3C,ADNP,ACTL6A,H1-5,LRWD1,DHX15,FOLR1,KLHL7,USP46,SASH3,HP1BP3,KDM2A,TRAF6,C2CD2L,AHSA1,HMGA1,DPY30,RBBP7,MCM6,RPS27A,UBE2A,MSL2,RFC2,SSRP1,AKT2,HSPD1,GADD45A,PCNA,EZH2,POLR2D,POLR2C,SART3,FEN1,ANP32A,SAP30 |
| 3.768e-04 | -7.88 | cytoplasmic sequestering of transcription factor | biological process | GO:0042994 | 9 | 8 | 18204 | 5365 |
FAF1,PSMD10,NFKBIA,G3BP2,CCDC22,SUFU,MDFI,IL10 |
| 3.787e-04 | -7.88 | transcription factor binding | molecular function | GO:0008134 | 598 | 217 | 18094 | 5411 |
SAP18,DUSP26,NAB1,RNF14,STAT1,NFYB,NR4A2,TRIM32,GTF2A2,CD34,HSPB1,HDAC6,VDR,TGFB1I1,SMARCB1,YWHAZ,SRC,CRTC2,ENO1,SP1,PAGR1,GTF2F1,CAND1,CDK9,ZNHIT6,BCL10,NCAPG2,NKX3-1,FAM89B,CBX5,DR1,VGLL4,RBBP8,TRIM6,SRI,RAD23B,SOST,BUD31,NUCKS1,FAF1,ACTN4,PADI2,DRAP1,MKKS,PHF12,LMO4,ACTB,ZBTB16,TAF11,IFI27,NBN,ZBTB17,PAX6,THAP7,LMO3,SRARP,EED,EP300,PCNA,GTF2I,APBB3,TFDP2,FOXP1,SOX9,HAND2,HIRA,SMARCD3,CHCHD2,TADA3,TFCP2,PHB2,DDRGK1,PRMT2,POU1F1,RPL23,TCF21,DHRS7B,TCF23,HEY2,NFKBIA,RUVBL2,KLF4,WWP2,ZNHIT3,DAPK3,E4F1,SMAD2,PPID,CNOT2,FBP1,RUVBL1,TAF9,FOXP3,MTA2,HDAC11,MED4,CGGBP1,SMAD4,CREBBP,NOP58,TP53,NR0B1,LMO2,EDF1,ANXA4,MYC,LDB1,MED17,CTBP1,SDR16C5,PIAS1,TERT,EIF4E,ELK1,TRIM24,SUFU,CDK5RAP3,TRIP4,HDAC3,MED30,TLE1,YWHAH,PPARA,ATF4,SMARCE1,STAT5A,PROX1,FKBP4,CREB1,TAF7,RBFOX2,ID4,RERG,ELOC,CPNE1,MTDH,LRIF1,GTF2B,NOTCH2,JUP,UBE2I,RBPJ,ADD1,AR,STK4,IFI16,CNOT7,RB1,GTF2A1,NLRP3,TRIB1,BBS5,THRAP3,CRY1,EZH2,AIP,HDAC5,PRKCB,CBX3,MAD2L2,MEF2A,GABARAPL1,TOB2,NFE2L2,BRMS1,PSMD10,CSNK2B,DDIT3,DDX5,PHF1,CALR,NAB2,MDFI,WBP2,CEBPG,HMGA1,COMMD6,PGR,DMAP1,PPARG,CREB3,FOS,JUNB,BCL6,SIN3A,C1D,KDM1A,MED29,RAD21,NIF3L1,NR1H2,DHX9,MEF2C,NR1I2,TRIM68,SETD3,CTNNB1,RPS3,CRKL,MAX,GMNN,PSMC5,HMGB1,TAF10,TTC8,SMAD3,H2BC9,HCLS1,EGR2,STAT6,SUMO1,PSMA6,JUN,BHLHE40,GTF2E2,LYAR,CXXC5 |
| 3.790e-04 | -7.88 | NOLC1 (nucleolar and coiled-body phosphoprotein 1) | protein interactions | 9221 | 302 | 112 | 19454 | 5460 |
MYC,SFN,CUL3,NOP16,RIT1,DNAJB6,POLR1B,BRCA1,YWHAZ,ZNHIT6,RPL19,ESR2,APEX1,SYK,MFAP1,ARCN1,GTF2IRD1,SAP18,COIL,G3BP2,YWHAH,YWHAG,XPO1,PIK3R1,RPL6,VPS26A,ARMC8,DDX23,EED,BRD9,FOLR1,DHX15,NOP58,LYAR,NUP153,E2F4,SUPT5H,RPS23,EZH2,NFKBIL1,SKA3,CHMP4C,NGB,RPS24,RPL31,ARGLU1,RPS4X,SSRP1,G3BP1,GNL1,RPL7A,SUB1,NAPA,UBE2H,RRP7A,PIP4K2C,CSNK2B,SYT2,TRIM24,CCNF,PELP1,ZNF330,VIRMA,SRPK2,CD2AP,DENND2D,RPS14,RPA2,METTL14,PRKCB,RNF113A,RTN4,RPA3,MME,PML,SIRT7,NHP2,PIAS1,AATF,BRIX1,RPL4,CSNK2A1,MOV10,AKAP8L,CDK12,BRD3,CD9,SMCHD1,CHCHD1,TES,ARL4D,SRP14,GTF2B,RCHY1,MDM2,DKC1,TMPO,ZBTB2,CDC5L,PSMB9,MAP1LC3B,YIPF4,RPL15,NUPR1,IK,RPL23A,SNIP1,TCOF1,RIGI,CAMKV,FGF12,KPNA2 |
| 3.792e-04 | -7.88 | FYTTD1 (forty-two-three domain containing 1) | protein interactions | 84248 | 148 | 61 | 19454 | 5460 |
H1-1,FYTTD1,CHTOP,FBXO7,MYC,CSK,RPL7A,HNRNPC,ESR2,ERH,APEX1,SRC,TUBB,YES1,RPL37A,PRKRA,CCNF,EFHD2,EIF4A3,RPLP0,APOBEC3C,GNG7,ATG16L1,NOP53,DDX39B,SNRPA,NKAPD1,NOL12,RPL10A,MAGOH,SNRNP70,GPRASP2,MOV10,RPL6,HNRNPL,THOC1,TSG101,PRR3,CYB5A,THOC2,KRR1,GNAQ,GNAZ,GLE1,PNMA2,GNG10,EXOSC8,SRSF4,SSRP1,RPL17,TSPAN7,LASP1,H1-6,NUP42,ZC3H11A,GNG5,CCNY,RTCB,GNA11,S100B,PPAN |
| 3.819e-04 | -7.87 | MTBP (MDM2 binding protein) | protein interactions | 27085 | 38 | 21 | 19454 | 5460 |
COX5A,RRM1,CCNA2,YWHAH,YWHAG,YWHAZ,COX6C,CDK8,TOPBP1,YWHAB,MFAP1,MRPL13,CLK1,RPL35,MIF,FBXW7,KRAS,COPE,ROMO1,MDM2,EGLN3 |
| 3.819e-04 | -7.87 | TFEB (transcription factor EB) | protein interactions | 7942 | 38 | 21 | 19454 | 5460 |
CFTR,YWHAH,XPO1,YWHAG,TOP3B,ATG16L1,RRAGA,MCAT,YWHAB,TAF9,YWHAZ,BAG2,HDAC5,ATP5PF,PPM1G,STT3A,STUB1,TFE3,TFEB,GPNMB,MITF |
| 3.845e-04 | -7.86 | soft_tissue-fat-liposarcoma-dedifferentiated | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-dedifferentiated | 19 | 13 | 16828 | 4835 |
TERT,PIK3CA,PTEN,TP53,KIT,RB1,CTNNB1,FBXW7,NUP107,EWSR1,HRAS,KRAS,IDH1 |
| 3.855e-04 | -7.86 | Cct3 (chaperonin containing TCP1 subunit 3) | protein interactions | 12462 | 43 | 23 | 19454 | 5460 |
CCT8,PFDN1,DNAAF10,EEF2,HACD2,SLC35E1,CCT5,SLC35F6,WDR77,PDCL,GFM2,ACTR2,PTEN,IGBP1,TUBA1B,CCNF,CCT7,PDCD5,TUBB,TCP1,XPO1,PFDN2,CCT2 |
| 3.855e-04 | -7.86 | ASB2 (ankyrin repeat and SOCS box containing 2) | protein interactions | 51676 | 43 | 23 | 19454 | 5460 |
SNRPD1,SSBP1,RAN,HNRNPA2B1,NFKBIA,JAK2,RPL35A,CAND1,HNRNPK,HMGB1,SPINDOC,HNRNPA1,NT5C2,ELOC,DCUN1D3,RAF1,CUL2,HNRNPD,SMAD9,EIF4B,HSP90AA1,UBE2D1,RNF7 |
| 3.882e-04 | -7.85 | behavior | biological process | GO:0007610 | 619 | 221 | 18204 | 5365 |
CRHR1,TUBA1A,GRID1,PRKCE,MCHR1,TMOD2,NPW,VLDLR,SOBP,KLHL1,USP46,EIF4EBP2,PTEN,ATP8A1,CNR1,PICALM,MAFG,SOD1,CARTPT,ATP1A2,CSTB,PAIP2,KIT,FEN1,TNR,GRIA1,GHRL,ADRB3,OXTR,SLC1A2,GABRG2,SLC1A1,GRPR,PAK6,SLC6A3,EP300,KRAS,FKRP,CEND1,DRD3,HAND2,PPY,PEX13,DKK1,AKT1,KCND2,NPY,BRS3,SLC6A1,RMI1,ELAVL4,MEF2C,PTPRZ1,UCN,HTR1A,PAX6,ADCY3,EGR2,ARL6IP5,PSEN1,PTN,SYT4,FXN,ABHD12,TACR1,GPRASP3,NPB,ZMPSTE24,ADM2,ORMDL1,HTRA2,PLCB1,GNAO1,BGLAP,PCDH17,CREB1,SLITRK5,USP2,HEXA,CSNK1E,PI3,EIF4E,HCRT,UBE3A,GLRA1,EPHA4,LRRTM1,PAK5,SLC1A3,FGF12,SNAP25,OPRM1,PPARA,NEUROD2,PRNP,GRM1,CNTFR,APLN,VDAC1,LDLR,HTR2A,REN,NPY5R,ADNP,FGF13,ANKH,GNG7,OPRL1,RAG1,GPR83,DRD1,CACNB4,CIART,HPGDS,JPH4,GPR176,SLC11A2,FOS,ATAD1,NPSR1,PIAS1,VPS54,TMEM74,GRM2,DPP4,ALDH1A3,TACO1,CNTN1,NDP,GLRB,NLGN2,TLR2,PPP1R1B,ASIC1,DBH,EIF4A3,CX3CR1,CRHBP,PPT1,KCNJ10,TRMT1L,SLC7A11,CAMK2N1,AGER,NOG,CDK5,DERL2,CXCL12,ZDHHC8,MME,YTHDF1,NPY1R,ORMDL3,HEXB,PRRT1,CHRNB2,CHRNA7,B2M,NCSTN,MECP2,SLITRK1,MKKS,EGR1,SLC6A4,S100B,TPBG,CNTN2,PDE1B,CLN8,NR4A2,FZD4,CAPN2,ARCN1,KCNK10,NTRK2,OPRK1,SLC16A1,NR2E1,BTG2,TSPO,SNCG,STRBP,TMOD1,CNP,SOD2,HOXB8,NTF4,FIG4,TP53,NPY2R,IDO1,GPR37,TAC1,PAFAH1B1,CHST10,BRINP1,DLG4,LEP,SLC4A10,ASTN1,ARF4,EPS8,CRBN,CCL11,C1QL1,HOMER1,SELENOP,NETO1,SLC25A46,SRC,ACSS2,TAS2R5,LARGE1,COMT,HELT,TBCE,MYG1,NEGR1,ATXN1L,EXT1,P2RY1 |
| 3.888e-04 | -7.85 | IRE1alpha activates chaperones | REACTOME pathways | R-HSA-381070 | 58 | 31 | 10285 | 3229 |
ARFGAP1,DNAJB9,FKBP14,DNAJC3,CTDSP2,SEC61A1,SULT1A3,CXXC1,ADD1,SRPRA,PLA2G4B,XBP1,SEC63,ZBTB17,SEC61B,SEC61A2,SSR1,GFPT1,EDEM1,SHC1,SEC61G,SEC62,PREB,GOSR2,YIF1A,GSK3A,SYVN1,PDIA6,SRPRB,HSPA5,LMNA |
| 3.888e-04 | -7.85 | RHOU (ras homolog family member U) | protein interactions | 58480 | 507 | 177 | 19454 | 5460 |
PIK3R2,NPM3,YKT6,CDC42EP4,PIP5K1A,ADIPOR1,ADM2,CNP,TMEM106A,SLC12A2,PICALM,STOM,JUP,MET,TUBA1B,GAB1,VAMP3,RPS12,GANAB,YES1,SNX3,NR1H2,GNAI2,FERMT2,SH3BP4,UBB,DEPDC1B,ZNF177,XPOT,EPHA2,CLEC7A,DLG1,HCAR1,EHD4,INSM2,SLC25A10,RAB1A,STX8,EMC2,SNAP23,CTNND1,CMPK1,HINT3,ZDHHC8,CASK,EHBP1,CDCA3,CAV1,DBT,ATP5MG,RELL1,TIAM1,ESYT1,SLC2A1,OSBPL8,ZFP64,TXNL1,NRBF2,NOTCH2,ETF1,ABCB1,PDLIM3,PKP4,CDC123,NIBAN2,MRPL16,MYO6,BLVRA,SLC7A11,JAK1,ACVR1B,AHCYL1,FLOT1,MCM6,MARCKSL1,LGR4,IFNGR1,PCDH17,RPN1,PLD3,STX12,DNM2,WDR6,ATP6V1A,SNX17,NEO1,GJA1,SPTAN1,RBIS,TMEM237,PRPF18,PPIA,PIK3R1,SLC20A1,LRP10,ARHGEF6,ITM2B,SEPTIN6,RAB9A,PGK1,FTSJ1,SPTBN1,CDC42,SDCBP,CSNK1G3,GIT2,NECTIN2,STX10,EPCAM,FAM110B,RAB2A,SLC25A1,ATP1A1,ABCE1,ERO1A,AKAP12,NEDD8,H2BC14,SLC6A8,SNAP29,BMPR2,TFRC,EXOC3,CERK,UGCG,STT3A,ADD1,SLC39A10,FLRT2,FCHO2,SLC38A2,STX6,TPM3,ZFAND2B,NOS1AP,IL17F,LANCL2,SLITRK5,BMPR1A,ABCC5,PACSIN3,ITGAV,USP6NL,SYK,UBAC2,PAK2,EIF4B,DOK4,FAM83B,NDFIP1,PSMA4,STX16,BRINP3,LAMTOR1,KIAA1191,SLC38A1,GNA11,CDK5,EFNB1,SLC20A2,EPHA4,PRPS1,VAMP8,NETO2,TMEM59,HGS,ANXA4,PTK7,SPINT2,MRAS,VAMP7,WWP2,SIVA1,CTNNB1,OLR1,PPFIBP1,NCK1 |
| 3.900e-04 | -7.85 | ANP32E (acidic nuclear phosphoprotein 32 family member E) | protein interactions | 81611 | 105 | 46 | 19454 | 5460 |
SNX2,TES,H2AZ1,KPNA1,MGMT,RPS2,H2AC4,H2BC17,DDX23,ATG7,AHCYL1,IMMP2L,MEPCE,RUVBL1,H3C1,G3BP1,RPS24,RUVBL2,EWSR1,RPL31,H2BC1,DMAP1,CBX3,SOX2,E2F4,ANP32A,TENT5C,PTEN,ZNF330,VPS72,DNAJB6,SMAD2,FYTTD1,EIF3G,KPNA6,FBXO7,MYC,G3BP2,HSCB,PMAIP1,HSPA8,FOS,BAP1,LMNA,POLR1D,ATP6V1C1 |
| 3.900e-04 | -7.85 | OSBPL3 (oxysterol binding protein like 3) | protein interactions | 26031 | 105 | 46 | 19454 | 5460 |
PRNP,KCTD3,EGLN3,PRPF18,ILVBL,EEF1AKMT3,TRAF3IP3,PTPN1,RAC2,RHOG,YWHAB,ARMC8,USP15,ACTR3B,YWHAG,YWHAH,ZBTB16,KRAS,TCEA2,TFPT,CPNE2,HDAC11,JPH4,RAF1,GABARAPL1,RHOJ,MTM1,ERH,TRAF1,PHTF2,ENO1,S100A6,YWHAZ,RHOB,SFN,PPP1CC,BTF3,NOP53,EP300,VAPB,TTI2,FAM161A,FGF13,GABARAPL2,KLRD1,OTULINL |
| 3.900e-04 | -7.85 | BEND3 (BEN domain containing 3) | protein interactions | 57673 | 105 | 46 | 19454 | 5460 |
PDIA6,COX8A,SIRT7,PAX6,MDC1,IMMP2L,ASF1A,TRIM37,RBBP7,KDM1A,TULP3,DDX39A,MORN4,FAM161A,MTA3,CERK,FAM81A,MTA2,RBPJ,VPS33A,EZH2,ARL4D,PHF21A,FOXP3,TRAF7,ZMYM2,ZNF330,CPSF1,TNIK,VIRMA,HSBP1,RBBP4,SNX1,SNRNP40,RIOK2,INSYN1,KANSL3,DPY30,SMARCA5,RIT1,RRP7A,MRPS26,PIWIL4,RPS2,DCAF4,CHCHD1 |
| 3.900e-04 | -7.85 | USP13 (ubiquitin specific peptidase 13) | protein interactions | 8975 | 105 | 46 | 19454 | 5460 |
STAT1,TXN,USP5,VIRMA,DYRK1A,RPP25,DLST,PTEN,FCER1G,NLRP3,MYC,UFD1,PRPF31,HMGB1,MRPL20,RPA3,RPA2,ATG16L1,THOC1,MITF,KCTD10,KCTD3,FZR1,CWC15,FUNDC2,CACYBP,SYNCRIP,SRP14,MCL1,SMAD4,TOPBP1,ATP6V1D,MOV10,CTNNB1,SIAH2,CSNK2A1,TRIM63,NEDD8,G3BP1,MDC1,RAD21,PABPC1,TLR4,YTHDF2,UBL4A,FAF2 |
| 3.905e-04 | -7.85 | PTPN21 (protein tyrosine phosphatase non-receptor type 21) | protein interactions | 11099 | 91 | 41 | 19454 | 5460 |
UBASH3B,SRC,RPL19,SNX18,VPS26C,MAGOHB,RPL35A,BAG3,CSNK2A1,YWHAG,YWHAH,CEP85,CSK,PFDN6,ARMC8,YWHAB,POLR1B,PFDN4,YWHAZ,ATOSB,DCAF5,RTCB,TMX3,AKAP1,RPL3,IFT52,GID8,MAEA,AHCYL1,RPL28,RANBP10,RASD1,NEK7,CDK4,KIF1C,AKR7A2,MOB3C,PARD6A,WWP1,PAK5,BPIFB1 |
| 3.905e-04 | -7.85 | KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1) | protein interactions | 10945 | 91 | 41 | 19454 | 5460 |
HSCB,RNF115,PSMD12,COIL,PEBP1,VIPR1,NMRAL1,UBE3A,TRAFD1,COX8A,SURF4,KDELR1,SIGMAR1,GPR35,GINM1,ARFGAP1,RABL3,DLG3,TMEM106A,SEC62,CFTR,PSMD4,TTC9C,TAX1BP1,RHOJ,PSMD6,APLNR,ESR2,SERINC3,VDAC2,ARF1,S1PR4,EDNRA,PTEN,SLC1A1,FA2H,SLC2A1,TCEAL9,LAMTOR1,UBE2H,UFD1 |
| 3.905e-04 | -7.85 | PBX3 (PBX homeobox 3) | protein interactions | 5090 | 91 | 41 | 19454 | 5460 |
RABAC1,GAD2,SYPL1,SFT2D2,MAGEC2,HIGD1C,DDX39A,CFTR,HOXB8,AGTRAP,TFIP11,TPD52L1,CPLX2,NUDT9,PTEN,MAB21L1,ZNF655,FAM177A1,SIN3A,RPRM,COQ8A,INPP5K,TRIM44,TRAF1,TMOD3,HNRNPL,TVP23B,MBLAC2,CAV3,INSYN1,TPM3,MYC,CIDEB,FAM222A,TMEM196,SYP,DESI2,RBBP8,SMPD2,PKNOX1,ZNHIT3 |
| 3.908e-04 | -7.85 | FURIN (furin, paired basic amino acid cleaving enzyme) | protein interactions | 5045 | 253 | 96 | 19454 | 5460 |
HUWE1,VWF,ARF4,BACE1,SLC25A11,ABCE1,ARPC3,ADAMTS1,GNAI3,FURIN,CMPK1,YTHDF2,TP53,SMAD3,SEC23A,KARS1,TPM3,AIF1L,CLEC12B,CLU,HELLS,BANF1,PRDX6,ZNF326,HSP90B1,SERPINI1,LEMD3,RABL3,TMEM106A,NTPCR,TMOD3,PPP1R10,TECR,DEK,GNAI2,LIG3,SMAP2,PRSS8,SEC61A1,ATP1B3,ARFGAP3,NAPA,ATP1A1,AP2A1,SORD,C9orf72,RHOBTB3,GORASP2,SLC20A2,ATP5F1D,AP1M1,SSRP1,POLDIP3,TFG,SLC25A5,NDUFA4,SCPEP1,MYO1B,RPN1,PDHA1,SERPINA5,TOP3B,ACTN4,ERLIN2,RAB1B,EIF2S1,SPTAN1,PXYLP1,NUP35,LANCL1,MRTO4,NRSN1,CDK5RAP3,TNFSF13,RAB5C,HNRNPA0,YTHDF1,BMPR1A,XRCC5,HADHA,CTBP1,MMP14,SLC25A3,PAFAH1B1,PGRMC1,RAB6A,MB21D2,CBX5,CHCHD3,VDAC2,AP2M1,MYO6,RIT1,SERPINH1,CUL3,MRPL16 |
| 3.943e-04 | -7.84 | TRPC6 (transient receptor potential cation channel subfamily C member 6) | protein interactions | 7225 | 80 | 37 | 19454 | 5460 |
EMC1,UFM1,SYVN1,TMEM147,EMC2,PDCL,FKBP1A,SAP30L,SPINK9,MX1,CCDC47,FUT8,SELENOI,SRC,WDR83OS,ALG5,MGAT1,RAB14,GATAD1,ACOX1,SRP14,UBE2G2,METAP2,TMEM30A,ATP1A1,SLC35C1,TRPC1,WDR20,EMC6,HSPA14,OST4,CSK,MARCHF5,TMEM208,EMC4,SUB1,PMM2 |
| 3.943e-04 | -7.84 | KCNJ6 (potassium inwardly rectifying channel subfamily J member 6) | protein interactions | 3763 | 80 | 37 | 19454 | 5460 |
DLG1,HSDL1,TMEM203,PICK1,ERG28,UNC50,ADRB2,GABBR1,CMAS,LEPROTL1,BET1,EDDM3B,UBIAD1,CNPY3,GOLGA5,BIRC5,RPRM,LRRC1,KCNJ3,MB21D2,HPF1,AIG1,SERTM1,FUNDC2,TSPO2,FAM118B,PMP22,MAP1S,TMEM208,ZDHHC24,FAM20B,HMOX2,TMEM107,FXYD6,ZBTB38,FIS1,CXXC5 |
| 3.976e-04 | -7.83 | vesicle-mediated transport | biological process | GO:0016192 | 1283 | 432 | 18204 | 5365 |
VAPB,TMEM50A,PPT1,MRGPRX2,RAB2A,SEC13,RAB11A,RAB6B,VAMP7,RANGRF,PITPNB,CORO1C,SEC22A,HMGB1,RAB6A,CDC42SE2,ELMO1,CXCR1,STX1A,CDK5,GOLPH3L,RAB11B,ARL4D,RHOU,VPS28,S100A10,PREB,ARHGAP12,TBC1D24,RHOB,PLEKHF1,AGER,STXBP6,HRAS,PYCARD,MYO1B,FOLR1,INPPL1,VAMP2,CIDEB,TRAPPC6A,PLEKHJ1,RAB31,CTTN,TRIM23,TBC1D10C,RAB9B,TBC1D17,CFTR,RP2,LMAN1,TBC1D5,EXOC3,TRAPPC10,AIF1,EXOC8,CCR2,ARF6,EXOC5,MAPKAPK3,CXCL8,BLOC1S2,PPFIA3,ARF1,CLEC7A,KIF3B,EHD1,LEPR,VPS4A,PLPP4,RAB30,TMEM87A,ACKR3,ITGAV,ARHGAP1,SCAMP5,HSPA8,CHMP1B,SGIP1,GHR,ADORA1,CCL8,TMED7,TLR4,TRIM27,ARF4,PTGDS,SNX2,AP1AR,RAB3C,RABIF,TMED5,GABARAPL2,MLC1,RHOJ,CHMP5,STX12,CHMP4C,SCFD1,ARCN1,ANKRD50,FCMR,LIN7C,LIPA,BET1,RAB39B,YIPF4,YIF1A,CCDC22,RIMS4,CD209,KLHL12,STBD1,DPY30,LRP3,FCN2,SYNGR2,CRYBA1,RAB29,SEC22B,JAGN1,TMEM115,RAB3B,WASL,ATP6V1C1,CMTM6,NAPG,VAMP8,RAB1B,KXD1,ATP6V1G1,SNX33,MARCHF3,AP5S1,VPS4B,ADRB2,ELMO2,TVP23B,C9orf72,RER1,COPZ2,CAV2,CYTH2,CCR1,CTBP1,MRC1,CHGA,IRF8,LRP12,HGS,SYNGR1,SLC66A2,WDR11,RNF126,VIPAS39,RAP1B,FCGR1A,COPS5,VTA1,ARHGAP25,CBL,ARL5B,AP5M1,OLR1,NAPA,BECN1,TRAPPC3,KIF1C,RAB3A,RAB13,PICALM,KCNB1,CCL5,PEG10,FCHSD2,PREPL,TMEM50B,RAB4A,RIMS3,IGF1R,MTMR6,GOSR2,CSNK1E,SNCB,GOSR1,ICAM3,CDC42,TRAPPC13,CCL3,RAB9A,ATP6AP2,LILRB1,SYNDIG1,ATP6V1D,STX8,SNAP25,SLC48A1,RNASEK,GDI2,CNIH4,TYROBP,ATP6V1A,STARD3NL,CAV1,ACHE,CSNK1G3,NECAP2,AGAP2,RAB1A,PLEKHF2,AP2M1,CAV3,VTI1B,COG1,OPHN1,CYTH1,SNX3,MYD88,VAMP5,PSEN1,MTM1,CD81,LILRB4,AP2A1,LMBR1L,UBAP1,SPTBN1,SCYL2,TMEM108,RAP1A,CRHBP,TUSC2,RAB33B,YES1,TFRC,RHOBTB1,GIT2,YKT6,CLTRN,RINT1,SYK,RAB14,ARFGEF1,RALB,FCGR2B,LIN7B,ACTR1A,FCHO2,TMEM167B,STX16,STX11,TMED9,SYNGR3,CLEC9A,SYP,PRSS12,ARL6,EHD3,NECAP1,EXOC2,STX6,LAMTOR1,SNAP23,USE1,NDP,TICAM2,NLGN2,RAB5A,VPS16,VAMP3,SFTPD,PICK1,VPS54,RAB35,YIPF5,DPP4,JPT2,PIK3CA,SEC23A,STX5,ARFGAP3,NLGN1,RAB22A,SNX10,SURF4,ARL4A,GPIHBP1,RAB8B,TMCC1,STX10,SYT2,TOM1,GOLGA5,NME1,LRP10,GTF2H2,CALY,SRC,SH3BP4,LEP,RAB40AL,SQSTM1,TRAPPC2L,PIK3CG,STX18,TM9SF4,SNX17,AP2S1,GOLGA7,KDELR1,TRAPPC4,SYS1,CUL3,SNX1,SNCG,EHBP1,ACAP2,DNAJC5,CPLX1,AP3S2,STX17,BICD2,TMED3,BET1L,RGP1,BLOC1S5,RAB5C,AP1M1,SNX5,NSG1,ATP6V1G2,PACSIN3,VAMP1,SNX18,CTNNB1,VPS26C,SLC1A1,RAB3D,KDELR2,RALA,ARFGAP1,WNT7A,CEBPE,TBC1D4,PHETA2,TMED4,VPS26A,DRD3,UBXN6,VPS39,STXBP1,TSG101,BCL2L1,PIP5K1A,TFG,PLA2G5,NCALD,STX7,VLDLR,CPLX2,PRKCE,RAMP3,FAM91A1,TEX261,RAB27A,BCAP29,SNX12,GRIA1,MET,ADRB3,FHIP1B,KIT,CD14,LAT2,LMBRD1,SYNRG,LRRTM1,MYO6,COPE,UBE3A,ARL11,FCER1G,FGR,SEC22C,GNAO1,CHMP1A,CAMLG,CEP19,VPS33A,NCKIPSD,VPS26B,TMED1,USP6NL,AP1G2,CPLX3,LDLR,AP1S2,SNAP29,MIA2,BVES,CDC42SE1,SNAP91,TSPAN18,CHMP2A,VAV2,SAR1B,TRAPPC6B,CHMP2B,TAPBP,CD36,SNAPIN,OPTN,SLC32A1,VPS18,SYN3,TRAPPC3L,LGI3,SCAMP2,EMP2,ILDR1,DNM2,LEPROTL1,OCIAD2,RHOBTB3,EXOC1,EHD4,SYT4,CPNE1,TRAPPC1,SFT2D2,CD9,CACNG3 |
| 3.989e-04 | -7.83 | Signaling by BMP | REACTOME pathways | R-HSA-201451 | 24 | 16 | 10285 | 3229 |
BMPR1B,CER1,SMAD4,SMAD9,BMPR1A,UBE2D1,NOG,GREM2,BMPR2,SMAD1,FSTL1,SMAD5,UBE2D3,CHRDL1,SMURF1,MIR198 |
| 3.991e-04 | -7.83 | extrinsic component of membrane | cellular component | GO:0019898 | 175 | 72 | 19108 | 5553 |
MYD88,TIAM1,JAK2,GNG10,PIK3CA,GNA14,PPP3CA,SOCS3,CTNNA1,PIK3R2,PICALM,CDH8,ATP6V1A,GNG12,PIK3CG,CNTFR,TRAF6,GNG3,JUP,GNG11,SLA2,GNB4,JAK1,NRBF2,TOLLIP,GNAI2,TIRAP,GNG13,WDR45,GNA11,PRNP,CDH11,SOCS4,ATP6V1C1,CTNND1,CDH13,GNAQ,CISH,SOCS5,GNAI3,SNAP91,ATP6V1G2,GNG2,RNF10,SNX10,CRKL,SOCS2,GNG5,SYN3,GNAO1,BECN1,EMC2,CTNNB1,ATP6V1D,GNB3,TAMM41,VAC14,DLG4,GNB1,STXBP1,CTNNA2,PIK3R1,PIK3R3,CDH7,IRAK4,GNAZ,SNAP25,AP2M1,PCSK9,GNG7,GNGT2,TRAF3IP2 |
| 4.015e-04 | -7.82 | negative regulation of smooth muscle cell migration | biological process | GO:0014912 | 39 | 22 | 18204 | 5365 |
MIR503,IGFBP3,AIF1,MIRLET7B,MIR218-1,MIR15A,MIR140,TRIB1,MIR21,MIR424,MIR34A,MEF2C,MIR638,ADIPOQ,MIR137,NFE2L2,MIR214,MIR223,ABHD2,MIR182,BMPR1A,MIR1298 |
| 4.041e-04 | -7.81 | DYNLL1 (dynein light chain LC8-type 1) | protein interactions | 8655 | 485 | 170 | 19454 | 5460 |
MAPRE1,UBE2H,NCKIPSD,CA2,DEDD,STK24,RC3H2,CFL1,PRKACB,RUNX1,ATP5F1A,KCNQ5,DYRK1A,DYNLT3,CTTNBP2NL,SNX3,RPGRIP1L,THAP8,LDHA,TRIM54,MSN,MRPS28,STOX2,MOB4,RPS3,OPTN,CCSER2,CCNF,WTAP,CDR2,HEXIM1,ZMYM6,RPA2,DCTN4,JUP,GABARAPL2,ATG16L1,PKIG,HSPA5,RGS2,PIAS1,KDM1A,NF2,SMCP,TXNDC17,NBN,BAP1,SNCG,RPA3,TSNAX,TNFRSF14,FAM53B,RPS2,SSX2IP,BECN1,PKIB,KCNJ10,GAPDH,ZMYND11,COPS5,HDAC6,PKIA,MRPS23,ZBTB2,CAV1,MBD5,FZR1,MCL1,CDR2L,COQ8A,AIFM1,NUPR1,CBX3,PPP3R2,UBR7,ZMYM4,ZMYM3,ACTR1A,EEF1A1,RPSA,BACH1,DYNC1I1,CAMK2G,PC,NTRK2,ABCE1,ERG28,GLUL,PPP1R12A,MAP1B,SLC25A10,RPS5,COP1,NTRK3,BTF3,CUL3,MYC,COPS7A,OTUD6A,MAD2L1,ACTB,DYNLL1,TUBB,ZMYM2,DLG4,NFKBIA,FAU,CSNK1A1,PIH1D1,EIF4B,PPT1,ADNP,AGGF1,KLF3,NEK7,PAFAH1B1,NDE1,SKP1,FBXO30,RNF41,UFL1,DNAL4,TERT,DCTN3,STK26,GPHN,HSPA8,LCA5,BCL2L1,RSBN1L,RB1CC1,DDRGK1,PPFIBP1,DYRK1B,PDIA3,IFI16,HSP90AB1,EGLN3,SLMAP,DYNC1I2,HNRNPL,COPS7B,DNAJB9,COPS2,EED,ZHX1,TRAF3IP3,PPP2CB,HOMER3,DNM2,WDR6,CCR1,RAB4A,NME1,EZH2,PPP2R1A,NUDCD3,GABARAPL1,RAF1,B3GALT4,RERE,PAX6,COPS4,SECISBP2L,ZNF609,TNF,ARB2A,PABPC1,NEK9,CTTNBP2 |
| 4.044e-04 | -7.81 | DHFR2 (dihydrofolate reductase 2) | protein interactions | 200895 | 287 | 107 | 19454 | 5460 |
RPL28,ETFA,TAS1R2,RTCB,CYB5B,CPE,CSTPP1,STIM1,RPN1,NUDCD3,TUBA1A,CBLN4,STBD1,MACO1,CACYBP,TCP1,ASIC1,CYB5A,WDR6,TMEM30A,ST3GAL4,DRG1,FKBP4,DDRGK1,PDIA3,PFDN5,RPL6,PTDSS1,PSMC1,STAU1,NSFL1C,HSPA8,TXNL1,TTC1,VAPB,TOMM22,PGRMC1,POLR2B,NLGN2,ATP6AP2,PSMD4,ATP5F1B,RBBP4,PSMD6,SEC61B,PFDN2,SERPINH1,CCT2,BTF3,PSMD1,BRINP3,SLC1A3,TMEM38B,VEZT,SLC6A8,EDEM2,FKBP8,DUSP19,HUWE1,CD1B,RPL3,IGF1R,TBC1D4,TFCP2,LBR,RPL15,CCDC47,PREB,LMAN1,DNAJC1,ADAM21,SLC39A10,PTPN1,SRPRA,CAMLG,DNAJC7,OSBPL8,POR,ESYT1,TMEM199,HSPA5,YKT6,RPL4,CLEC12B,MTDH,SPCS2,TEX264,HSP90B1,FGFR1,SLC12A2,TMEM106A,CCL3,PSMC4,SEC22B,UBB,SEC63,RPL22,LDHA,PSMC5,STUB1,ENO1,TUBA1B,ATP1A1,OAT,HFE,HMOX2,ST13 |
| 4.049e-04 | -7.81 | cellular response to type II interferon | biological process | GO:0071346 | 82 | 39 | 18204 | 5365 |
IFNG,IL12B,TP53,STAT1,RAF1,GAPDH,TLR3,CCL2,TNF,STXBP1,CCL5,JAK2,CD47,PDE12,DAPK1,CDC42,IRF8,MRC1,CDC42EP4,ZYX,JAK1,IRF1,TLR2,SYNCRIP,CCL3,CDC42EP2,VPS26B,RPL13A,DAPK3,FASLG,ACTR2,TLR4,IFNGR1,CLDN1,STX8,AIF1,VAMP3,CD58,AQP4 |
| 4.057e-04 | -7.81 | ARGLU1 (arginine and glutamate rich 1) | protein interactions | 55082 | 163 | 66 | 19454 | 5460 |
RPA2,FGFR1,ZC3H14,SNRNP27,CFTR,DET1,PSENEN,NPM3,RBM22,NHP2,SAP18,PEBP1,RPA3,HSPA8,RNF113A,COMMD2,COP1,UBE2H,CASC3,MYC,SUB1,RUNX1,IFI6,SH3BGRL,UBE2V2,SEC63,TCEAL7,SRPK2,CCNF,EZH1,CSNK2B,PRMT5,EZH2,IK,AAMP,H2AJ,TP53,MTCH2,KRAS,RBBP7,SRSF4,MRPL22,DPM2,SNIP1,GLUL,ARGLU1,EWSR1,HAPSTR1,DNAJB4,SRSF7,DHX9,SNRNP70,HAX1,ANKRD50,BRD3,UQCR11,ZCCHC10,HNRNPL,CD151,SNRPA1,COMMD6,DKC1,CDC5L,FOLR1,SRSF1,EED |
| 4.057e-04 | -7.81 | SLX9 (SLX9 ribosome biogenesis factor) | protein interactions | 85395 | 163 | 66 | 19454 | 5460 |
RPS12,RPS9,RBMX2,FGFBP1,ZNF330,FAU,FAM177A1,CCNF,APLNR,ANAPC15,RPS17,RIOK2,LDHB,MTG2,MYC,CABCOCO1,UBE2H,DNAJB6,RPS5,EMG1,PNO1,RPS28,AATF,ZDHHC17,FBXW7,RPS15,PSENEN,RPS14,TRMT112,CSNK1A1,TES,MYBL2,KRR1,NAP1L5,SPPL3,RPS16,NOB1,DDRGK1,XPO1,YWHAH,RPS2,ZCCHC9,DDX23,COX8A,RPS24,EWSR1,PICK1,ATF3,FGF3,S100B,RPL31,GTF3C3,RPS13,RPS27A,RPS4X,NOC4L,RPS7,TNPO2,JUN,RPSA,CSNK1E,BUD23,RAF1,RPS23,RPS11,CBX3 |
| 4.065e-04 | -7.81 | ATG5 (autophagy related 5) | protein interactions | 9474 | 128 | 54 | 19454 | 5460 |
OPTN,ESR2,LDHA,STAT1,SAMHD1,ATG101,GJB2,MYC,USP13,CCHCR1,ATG3,CCT2,FAS,SQSTM1,MAVS,RAB33B,PGK1,CSRP1,FBXW7,NF2,CAPN1,ATG16L1,NLRP6,LMNA,GJA1,PSMB5,EEF1AKMT3,DHX15,CAV1,CCT7,RAB33A,XPO1,RPL6,KXD1,BCL2L1,RB1CC1,PSMD10,TIAM1,BCL10,DHX9,HSD17B10,RPL23A,PALM2AKAP2,MYD88,MDC1,RPS4X,ETFA,GJB1,PSMB11,MAP1LC3B,ISG15,BIRC5,CAPN2,TAB2 |
| 4.065e-04 | -7.81 | EIF2B2 (eukaryotic translation initiation factor 2B subunit beta) | protein interactions | 8892 | 128 | 54 | 19454 | 5460 |
EIF3K,SELENOT,VAMP3,LMBR1L,RTRAF,SYT2,RPL10,UBB,GPR17,C9orf72,CD226,RIT1,RPA3,CD40,RFC4,CMAS,PIP4P1,UBA52,ATG16L1,SPTBN1,AGO1,SEC62,ZNF326,EIF2B3,RPA2,PIP4P2,MFAP1,PCDH9,EIF2B5,EIF2S1,VTI1B,FAM174A,DDRGK1,ATG7,XPO1,NCK1,SMDT1,DDX1,TMEM164,HNRNPA2B1,ABCF1,MRFAP1L1,DHX9,RTCB,EFNB1,KRAS,PCGF6,COMTD1,CLEC2B,BZW2,CA14,SIGLECL1,STX12,ILF2 |
| 4.065e-04 | -7.81 | ATP6V0C (ATPase H+ transporting V0 subunit c) | protein interactions | 527 | 128 | 54 | 19454 | 5460 |
ATP5F1A,ZCCHC12,SCN3B,OPRM1,CREB3,KDSR,RIT1,ATP5MC1,LAMTOR1,RETREG3,PI16,CYB5R3,VAMP3,ATP6AP2,ERH,TECR,RHOJ,ATP5F1B,BORCS6,RNF182,PDCD1LG2,SLC35E3,STOM,HBB,CDK1,LMNA,ATP5PO,TMEM185A,PSMA3,ATP5IF1,TAPBP,VSIR,ATP6V1G2,CERS2,SLC7A1,SLC38A7,ATP5MG,MDFI,TMEM199,FAM241B,CYB5A,SSMEM1,DNAJC1,ARF6,ATP5PB,STX12,TMEM31,EDA2R,BSCL2,ATP5PF,TMEM87A,RIGI,ATP5F1D,KRAS |
| 4.076e-04 | -7.81 | EFHD2 (EF-hand domain family member D2) | protein interactions | 79180 | 108 | 47 | 19454 | 5460 |
KBTBD4,E2F4,CENPM,SOX2,GTF2E2,CHMP4C,ACTR2,ARPC3,NUPR1,IDH1,OLA1,RIGI,HDAC6,FCGR2A,LRRC40,RAB35,TYMS,MTAP,DCK,ECHDC1,PRNP,ATG16L1,SNRNP27,RPA2,TMOD1,RDH12,RPA3,BAP1,NMRAL1,ARPC2,STAU1,FBXW7,HSPA5,MYC,PTPN11,GFUS,RAB11A,BTF3,MTPN,USP14,GMPS,FYTTD1,BICD2,PAPSS2,ENO2,MB21D2,ESR2 |
| 4.076e-04 | -7.81 | PYGL (glycogen phosphorylase L) | protein interactions | 5836 | 108 | 47 | 19454 | 5460 |
IKBKB,COPS5,GPRASP2,HSPB8,DCAF4L2,PRNP,H2AZ1,PSMB5,UBE2N,GGCT,STBD1,GBE1,TP53,SAR1B,PTGES3,HUWE1,EMC2,HSD17B10,UBE2H,SPOP,BRCA1,MYC,TBCE,SNRPB2,VIRMA,PYGM,KCTD9,RPGRIP1L,CCNF,UBE2M,SCLT1,RPA2,PSMB7,IDH2,CFTR,PSMC4,PYGB,EIF5B,EMC1,FBXW7,STAU1,HMCES,PGK1,HSPA8,BAP1,RPA3,SIRT7 |
| 4.118e-04 | -7.80 | EML3 (EMAP like 3) | protein interactions | 256364 | 56 | 28 | 19454 | 5460 |
FTL,SKP1,CHCHD2,PRKCB,NEK9,HAUS2,PNMA2,TUBB4B,AGGF1,CDK1,SCHIP1,NEK7,INSYN2A,RAF1,TOP3B,DYNLL1,SUMO2,THAP8,CDK6,MAP1LC3A,YWHAB,YWHAZ,TUBG1,SMAD4,ATG7,INSYN1,YWHAG,YWHAH |
| 4.118e-04 | -7.80 | ERN1 (endoplasmic reticulum to nucleus signaling 1) | protein interactions | 2081 | 56 | 28 | 19454 | 5460 |
SEC63,VIRMA,SRPK2,NMI,SEC61B,SYT2,SEC61A1,STUB1,HSP90AA1,SLC6A1,TRAF6,USP14,COPS5,HMGCS1,NTAQ1,MARCHF5,MYC,HSPA5,PSEN1,CLEC12B,ADIPOQ,DERL1,PDIA6,FBXO11,SYVN1,TRAF2,CNPY3,TP53 |
| 4.118e-04 | -7.80 | FMC1 (formation of mitochondrial complex V assembly factor 1 homolog) | protein interactions | 154791 | 56 | 28 | 19454 | 5460 |
ATP5PD,SSH3,GRPEL2,SLC1A1,S100A6,LMBR1L,COX4I1,LIG3,UBE2H,KLHL22,MTRF1,CLPX,PMPCA,WWP2,MCCD1,STOML2,POLDIP2,ABHD10,CHCHD2,MRPL57,SLC25A51,OXCT1,ATP5F1E,ATPAF2,ATP5PO,NDUFAB1,SNAP29,ATP5PB |
| 4.118e-04 | -7.80 | USP18 (ubiquitin specific peptidase 18) | protein interactions | 11274 | 56 | 28 | 19454 | 5460 |
MAVS,DHX9,PCNA,RPS27A,ZDHHC17,HUWE1,HDAC3,SOX9,EEF2,ISG15,EEF1A1,DUSP14,STAT6,MYL6,TAB2,NME1,TMEM14A,CBFB,TAB1,CCAR2,TRIM54,STAT2,CTNNB1,SAMHD1,MOV10,BCL2L1,BECN1,IKBKB |
| 4.118e-04 | -7.80 | EPN3 (epsin 3) | protein interactions | 55040 | 56 | 28 | 19454 | 5460 |
ALKBH5,FEM1B,NTAQ1,VPS39,TRIM32,ESR2,SMURF1,UBB,KCTD10,KCTD3,TNKS,HRAS,TPD52L1,RNF8,HSP90B1,EHD1,UBA52,INSIG2,CMPK1,TOP3B,RNF11,RPS27A,TNKS2,LITAF,TRIM26,FAM168A,TNFAIP1,RTCB |
| 4.119e-04 | -7.79 | nuclear transport | biological process | GO:0051169 | 245 | 97 | 18204 | 5365 |
TP53,HNRNPA1,KPNA1,NOP9,NUP107,THOC2,STK4,THOC6,DDX39B,MAGOHB,PHAX,NCBP2,AHCYL1,EIF4E,TRAF3IP2,THOC1,HSPA8,CHTOP,NXT1,TNPO2,RPS15,STK3,SQSTM1,HNRNPA2B1,NUP42,HIKESHI,RPAIN,PHB2,TXNIP,SMG5,CDAN1,KPNA2,XPOT,PRKAG1,IPO8,FBXO22,ALKBH5,FYTTD1,CDKN1B,GLE1,TNPO3,FAM53C,SMURF1,ALYREF,RAN,PIK3R1,RPL23,EGR2,CAMK1,PPP1R10,SFN,DESI1,RBM15B,UBE2I,CALR,RANBP6,CHP1,XPO1,POLDIP3,ENY2,MAGOH,NFKBIA,NXT2,ING1,EIF4A3,NUP37,SEC13,ANP32A,AKT1,CTDSPL2,FAM53B,RANGRF,PPP3CA,SYK,LMNA,ZC3H11A,THOC3,XPO5,CDKN1A,NUP62,PML,HCLS1,CSE1L,SPRN,DDX39A,NUP35,CITED1,ABCE1,STRADB,RSRC1,DRD1,KPNA6,CCHCR1,POLA2,NUP153,CASC3,NUP50 |
| 4.132e-04 | -7.79 | RMND5A (required for meiotic nuclear division 5 homolog A) | protein interactions | 64795 | 169 | 68 | 19454 | 5460 |
LILRB4,KRT8,SPPL3,CCAR2,EGLN3,INSYN1,SPON1,MRPL18,NME2,TCEAL9,SMAD9,ARMC8,RPL31,MAP1B,PSME1,MAEA,MKLN1,RPL3,RPL23A,BAG2,HUWE1,PSMD12,SECISBP2L,LECT2,UBL4A,NEU1,LY6H,JPH4,EMILIN3,SOX2,TFRC,NDUFS6,ADAMTS1,HBP1,STUB1,PRMT5,PSMC5,SGTA,BMP1,TENT4A,POLR2B,VIRMA,PSMB2,ZMYND19,MRM2,CDKN3,PSMA4,SEC13,PSMD1,LAMTOR1,MYO6,YPEL5,UBE2H,HTRA2,DDX39B,GID4,GID8,RMND5B,SQSTM1,DDX5,UFL1,PDHB,KDM1A,RANBP10,LAP3,PSMB3,PSMB7,CDK1 |
| 4.144e-04 | -7.79 | negative regulation of catalytic activity | biological process | GO:0043086 | 445 | 164 | 18204 | 5365 |
CORO1C,DFFA,PTPN22,SPOCK1,SERPIND1,AKT1,SIAH2,RGS2,ARFGEF1,IL1B,HEXIM2,TMBIM6,HDAC6,MIR152,RPS7,PYCARD,HRAS,PKIA,CCAR2,DUSP10,STK38,DRD3,DBNDD1,CAMK2N1,DPEP1,SPRED1,ADIPOQ,TNF,RAF1,DUSP3,MIR24-1,CHP1,ROCK2,DUSP22,GSTP1,HYAL2,SERPINB1,LAMP3,MT3,GPX1,PPP1R1B,DUSP1,PLN,CSNK2A1,EIF4A2,MIR17,MIR20A,GSKIP,GADD45A,CAMK2N2,GNAI2,CBL,GRM2,CAAP1,CSTA,MIRLET7B,CCR2,CSTB,ATP5IF1,PAK2,BANF1,MIR378A,SLC8A1,TRIB1,IGBP1,ATP2B4,MAD2L1,TSG101,PTEN,MIR29C,FKBP1A,MIR339,PKIB,CAND1,LRP6,MACROH2A1,CDKN1A,TESK1,CDK5RAP3,PIH1D1,GSK3A,NFKB1,DEFB114,ABCE1,RB1,SERPINI1,PPP1R12A,PTPRQ,TIMP4,SRC,SH3BP4,BAG2,INPP5K,PTPN1,SERPINH1,ERRFI1,MIR130B,HEXIM1,KLF4,SPRY1,SOCS4,MIR590,THY1,TMBIM1,RNF34,TRIM27,SERPINA5,IFI6,CST3,NOSIP,TAF7,YWHAG,GNAI3,IFNG,TP53,SERPINB11,ROCK1,PDCD4,TIMP3,SERPINA1,RTRAF,GNAQ,MIR34A,PPIA,MMP9,DUSP19,MIR15A,HSPB1,PRDX3,PKIG,SOCS5,GFI1,CDKN1B,PPP2R5A,MIR711,SERPINB6,SERPINB10,IFI16,MIR218-1,DNAJB6,SFN,TFIP11,PPARG,MIR21,LILRB4,RPL23,PAQR3,SERPINA3,MAD2L2,LGALS3,CAV1,IKBKB,GAPDH,SERPINB9,CYP27B1,FKBP1B,CDKN2D,MIR210,VEGFA,HP,CEP85,TIMP1,CAV3,UBASH3B |
| 4.146e-04 | -7.79 | TTR (transthyretin) | protein interactions | 7276 | 94 | 42 | 19454 | 5460 |
ATG7,SCGB1D1,ST13,PIK3R1,TAF5L,TNFAIP3,ATF4,HSP90AA1,AGPAT1,LANCL2,PSMD14,ALB,INPP5K,FEZ1,NPC2,CTSB,PRNP,DERL2,ACTB,SUMO3,SOX2,EEF1A1,TUBA1A,CFTR,CCNA2,MTMR6,HNRNPH3,SELENOF,CCR1,CDR2,NDUFA5,AGER,SYVN1,ERG28,DERL1,DDR1,MT3,PHYHIP,CLU,RNF115,TTR,ZBED1 |
| 4.146e-04 | -7.79 | DUSP9 (dual specificity phosphatase 9) | protein interactions | 1852 | 94 | 42 | 19454 | 5460 |
TMX3,RAB5A,GNA11,PRIM2,DUSP9,TMUB1,PFDN1,SRM,HSCB,NDUFAF3,ELP3,PPP2R1A,MAPK10,PGRMC1,CDK4,RAP1A,CYB5B,OTULIN,GNAI3,PTRH2,UBAC2,VAPB,AP1AR,ARL10,DUSP6,HRAS,GNAI2,SEC63,GNB1,TMEM97,PPIA,EGLN3,FBXO22,HMOX2,MBLAC2,PFDN5,RAB5C,PFDN6,PFDN2,PFDN4,PSMD10,TMEM11 |
| 4.146e-04 | -7.79 | STING1 (stimulator of interferon response cGAMP interactor 1) | protein interactions | 340061 | 94 | 42 | 19454 | 5460 |
MAP3K14,HM13,USP2,USP3,TRIM32,IFI16,USP13,TMEM100,REEP6,SMCHD1,TRAF6,MUL1,IKBKB,SEC61B,STX5,SEC61A1,HSD17B11,STT3A,TECR,TOMM70,CGAS,DAPK3,YIPF5,OTULINL,TRAF2,FAF2,TP53,DDAH1,TBK1,CCDC47,SURF4,RPN1,DERL1,MAVS,IRF3,TMT1A,CD40,RNF26,RIGI,LEPROTL1,RNF115,RNF5 |
| 4.163e-04 | -7.78 | SMURF2 (SMAD specific E3 ubiquitin protein ligase 2) | protein interactions | 64750 | 172 | 69 | 19454 | 5460 |
H2AX,TRAF2,SMAD1,TOP3B,RPSA,ILF2,EZH2,IRF8,PPID,CCM2,KRIT1,EFNB1,LDLRAD4,RAB13,SEMG2,SLC25A5,RNF20,RPS27A,SRSF4,NEDD8,TGFBR2,SATB1,XPO1,RAB22A,GNG2,NKIRAS1,RPS2,ID1,HSPB1,USP15,SMAD4,UBE2D1,ARHGAP5,SNRNP70,FKBP4,SMAD3,ACTA2,MRPS23,HNRNPL,UBA52,RASL12,UBE2M,STAMBP,KCTD12,LMNA,WWP1,RLIM,MAVS,DVL2,IRF3,RNF11,MRPS7,UBE2D3,PDE4B,SMAD2,SETD7,TXNIP,DNAJC10,ING2,RRAS2,UBE2I,RAN,TNFRSF1B,SMURF1,UBE2L3,TNPO3,SMAD5,VIRMA,RAB14 |
| 4.163e-04 | -7.78 | TBL3 (transducin beta like 3) | protein interactions | 10607 | 172 | 69 | 19454 | 5460 |
RPA2,UTP15,RPA3,SIRT7,EXOSC4,APPBP2,WDR3,RP2,GPIHBP1,STAU1,RPL4,G3BP2,AATF,MYC,CACNB4,SFN,USP14,DNAJC8,SPOP,BRCA1,FTSJ3,RC3H2,EXOSC1,DNAJB6,POLR1B,UBE2H,PSPC1,LMBR1L,FAIM,CCNF,CIB2,FAM43A,SNRNP40,TUBB,ESR2,TP53,E2F4,URM1,SOX2,LGR4,CHMP4C,NUPR1,RHOBTB1,RPL31,RPS24,BAG2,KRAS,PSEN1,GOLGA7,GRSF1,IFI16,WWP2,ATG7,DDRGK1,CHCHD1,MPHOSPH10,MPHOSPH6,BRD3,KRR1,EED,ARHGAP25,LDLR,PWP2,SPPL3,RPS16,NOP58,DKC1,SURF6,WIF1 |
| 4.167e-04 | -7.78 | ECSIT (ECSIT signaling integrator) | protein interactions | 51295 | 226 | 87 | 19454 | 5460 |
TIMMDC1,MTRES1,P2RY12,NDUFC2,TMEM126B,SQSTM1,GFM1,MAVS,CYP2C18,PSEN2,SLC25A51,LPAR1,TUFM,EXOSC1,DNAJC19,SYNGR1,SMURF1,VIRMA,APOO,SMAD1,NDUFA2,MRPL11,NDUFS3,LPAR2,SOD3,TLR4,PSEN1,FASTKD5,FARSA,DNAJC30,NFKB1,RAB3A,SMAD4,TMEM70,CHCHD1,SSBP1,MGME1,COX4I1,NDUFAF3,CXCR4,NGRN,TSPAN15,FBXW4,EXD2,AZGP1,HSCB,NDUFS2,RHEB,MTG2,AUH,KDSR,MYC,PMPCA,GPBAR1,FAS,RETREG3,TACO1,S1PR4,LMBR1L,CCDC90B,PARL,NDUFAF4,APEX1,B4GAT1,PRDX2,FAF2,ACTN4,PPP2R1A,FAM136A,CYP2C8,PDHA1,HINT2,NDUFB5,CYP2C9,MRPS17,IMMP2L,COA1,MTRF1,MRPS26,STAMBPL1,NDUFB8,RHOG,TRAF6,GATD3,NDUFS8,DHX15,RMND1 |
| 4.168e-04 | -7.78 | Ubiquitin–Proteasome Pathway | SMPDB pathways | SMP0063816 | 28 | 20 | 1369 | 531 |
PSMB6,PSMA4,PSMA2,PSMA3,UBB,PSMB5,PSMB7,PSMC1,PSMC3,PSMA6,PSMB1,PSMD4,PSMC5,PSMB3,PSMC4,STUB1,PSMA1,PSMB2,PSMB4,PSMA5 |
| 4.172e-04 | -7.78 | UBE4B (ubiquitination factor E4B) | protein interactions | 10277 | 131 | 55 | 19454 | 5460 |
PGRMC1,CNTN2,VPS4B,VAV2,RPA2,RPA3,STAU1,EYA3,UBE2D3,UCHL3,LRRC73,PYCR2,MYC,FBXW11,DLST,LMBR1L,STUB1,MRPL53,SF3B4,VIRMA,UBE2L3,NDUFA2,TP53,TOP3B,RBM12,UBE2V1,PPIF,NUDCD3,TMEM165,CAPZA2,RAD23B,HGS,ZRANB2,TTC4,SRPRB,UFM1,AHCYL1,VPS26A,EDEM1,TRA2A,KLHL22,UBE2D1,SMAD4,PPP3CA,CBL,DNAJC7,FEZ1,HRAS,PSMB1,THY1,LDLR,IGBP1,HNRNPL,TTC9C,MDM2 |
| 4.188e-04 | -7.78 | ACTN1 (actinin alpha 1) | protein interactions | 87 | 312 | 115 | 19454 | 5460 |
CLU,HSPA5,PIAS1,PML,SIRT7,MYH2,BAP1,RPA3,INPPL1,MTDH,JUP,RPA2,CYC1,GIT2,CDAN1,RPS14,CFTR,TXN,DAPK1,CTSB,SRC,VIRMA,SMURF1,CTNNA1,CCNF,MOB4,MAPRE1,FXN,NRP1,CDC73,USP14,KPNA2,PRDX4,PSEN1,FAF1,CAPZA2,DISC1,TFCP2,NUPR1,FURIN,RNF8,CAPN2,FBP1,MAP1LC3B,PRNP,CDK9,PTPN1,TES,SSX2IP,USP2,DPP4,TPM3,DAG1,CD81,HDAC6,MYOZ3,CYFIP2,COIL,CSRP1,PYGB,NKAPD1,DDX39B,AKAP1,NMRAL1,HSPA8,APPBP2,PPT1,PIH1D1,RRAGA,WDR77,PPP1CB,APEX1,ESR2,GADD45G,VDAC2,CKB,ICAM1,HSP90AA1,SFN,MYC,MCM3,TOMM40,BTF3,TRIM37,PSMA1,SAR1B,ZYX,CDK5,TRIM21,OAS1,CAAP1,CHMP4C,EZH2,CYB5B,CDK5R1,RND3,TOP3B,KIF2A,TUBA1A,ACTN4,PPP2R1A,ISG15,FAF2,SPTAN1,RPS10,EIF2S1,HSP90AB1,PHB1,GJA1,AGR2,DRG1,HSPB1,CBL,SYNJ2BP,CTNNB1 |
| 4.191e-04 | -7.78 | MRPL21 (mitochondrial ribosomal protein L21) | protein interactions | 219927 | 175 | 70 | 19454 | 5460 |
TMEM70,SNRNP70,CHCHD1,MRPL18,RHOG,MRPS26,GRSF1,MTRF1,TRA2A,MRPL9,HNRNPA1,MRPL50,MRPL24,MALSU1,COX4I1,SSBP1,MRPS9,GATD3,MRPL49,MRPL51,GFM2,ILF2,MRPL47,MRPL11,TOP3B,METTL15,AURKAIP1,FAF2,GTPBP8,IMMP2L,FASTKD5,HSPD1,PREPL,MRPL52,LIPA,HINT2,DNAJC19,PMPCA,CUL3,AUH,MTG2,MYC,TUFM,FBXO7,RPL13A,MRPL23,PARL,RPL19,CCNF,TACO1,MRPL53,RPS9,MRPL13,RPA2,MRPS18A,ACACA,MTRES1,RBMS2,MRPL12,MRPL10,MRPL41,MRPL40,HSCB,TRA2B,MRPL17,MRPL20,NHP2,EXD2,NGRN,GFM1 |
| 4.191e-04 | -7.78 | ZGPAT (zinc finger CCCH-type and G-patch domain containing) | protein interactions | 84619 | 175 | 70 | 19454 | 5460 |
DVL2,PRPF4,PPIH,C1D,PSENEN,LDOC1,LSM8,ATG16L1,TXNL4A,BEND5,SUMO1,SNRNP27,CPLX2,USP39,LSM2,THAP6,CDR2,TFIP11,CCNF,EZH1,SCNM1,CTNNA1,SNRPD2,TRIM27,SNRPD1,TRIM54,SNRNP40,SPCS1,ESR2,APEX1,MYC,STAC3,PRPF31,ANAPC15,CEP70,SNRPB,LSM6,SERTAD3,CCHCR1,ZNF177,RBBP7,KRAS,LSM4,TOLLIP,S100A10,CDCA7L,SNRPG,TOP3B,H2AJ,THAP1,EZH2,MTA2,SART3,SNRPE,CEP57L1,LCA5L,LSM5,SNRPA1,SNRPD3,EGLN3,CEP19,DHX15,ZNF24,INSYN1,DDX23,LSM3,SSX2IP,POU5F1,ANKRD50,ZNF688 |
| 4.207e-04 | -7.77 | DDX28 (DEAD-box helicase 28) | protein interactions | 55794 | 220 | 85 | 19454 | 5460 |
CCL3,RBMS2,MRPL12,MRPS34,MRPS18A,NDUFA5,NGRN,ATP5IF1,MRPL57,NDUFS2,HSCB,MRPL17,NME4,MRPL20,MRPS7,CUL3,PYCR1,PYCR2,AUH,USP13,MTG2,MYC,PPP1CC,MRPS25,RC3H2,MRPS16,MCAT,DLST,METAP2,TACO1,MRPL13,MRPS28,LAMTOR3,MATR3,RPL10,NDUFA2,MRPL11,SUPT5H,RAF1,TOP3B,ATP5PB,METTL15,SOX2,DDX39A,DUSP1,NDUFS6,NDUFS3,PDHA1,PNMA2,MRPL49,NDUFA12,ILF2,PSME1,MRPL52,SRSF7,EMC2,MRPS18B,HINT2,USP30,MRPS33,HNRNPDL,MRPS35,IFI16,MOV10,GRSF1,DDRGK1,ACTL6B,NDUFV2,MRPL9,HNRNPA1,MRPL18,ATP6V1D,POU5F1,MRPS26,MRPS9,ATP6V1A,GATD3,PRR3,MRPL50,HNRNPL,RAB11B,MRPL24,MRPS23,NDUFS8,MALSU1 |
| 4.212e-04 | -7.77 | MED4 (mediator complex subunit 4) | protein interactions | 29079 | 444 | 157 | 19454 | 5460 |
HADHA,DCTN3,PMAIP1,RAB5A,MED13L,NMRAL1,ATP5IF1,LCA5,NSFL1C,MED11,NDE1,ACTL6A,PIH1D1,MED31,NUFIP2,MED23,ZMAT2,GTF2F1,POLR2F,POLR3B,AP2M1,FAM91A1,ACAP2,ESR2,POLR2B,MED17,TAX1BP1,RNF40,SMARCE1,RIT1,TNFAIP8,ATG3,RBM27,MED10,GCC1,SKA1,PDIA6,EWSR1,TRIP4,NEK9,ZYX,CCAR1,MRPS17,SSNA1,KRAS,PSMA2,FOXJ3,JUN,MED9,SPC24,RAF1,VDR,HGS,POLR2D,POLR2C,SKA3,PPFIA3,COPS2,CORO1C,POLR2L,RPRD1A,THOC2,CNTROB,SPTAN1,SNX1,EXOC1,INSYN1,ZCCHC10,WWP2,NDC80,PDAP1,SMAD9,HNRNPD,NR1I3,SQSTM1,TCEA1,LSM12,ARHGEF6,NBN,DVL2,RPA3,PPM1G,BRIX1,POLR1H,ZC3H15,OIP5,FBXW7,SGF29,POLR1D,CD2AP,FBXL19,MED30,PIP5K1A,EEF1E1,ATG16L1,HAUS2,SH3GLB2,GIT2,HBB,PTPN22,SDCBP,RPA2,POLR3H,ALB,PSMC5,SEC61A1,GNAO1,HOMER1,CHPF,AR,SEC13,MED22,CAP2,CCHCR1,AP2A1,SMAD2,STN1,CCDC22,PIP4K2C,HAPSTR1,MRFAP1,MAP1B,SNRPG,PDRG1,THRAP3,FGF12,HUWE1,CTNNBL1,EXOSC8,SMAD1,RPAP2,ACTR1A,ATP5PB,SNAP29,TBK1,BIRC5,POLR2G,TNFAIP8L1,CDK8,PSMB1,GTF2B,SMAD3,ATP5PD,DBT,THOC1,POLR2I,FZR1,ERCC3,KARS1,BRD3,USP15,SSX2IP,PSMD7,ECD,MED29,MED21,MED27 |
| 4.213e-04 | -7.77 | gamma-aminobutyric acid transmembrane transporter activity | molecular function | GO:0015185 | 9 | 8 | 18094 | 5411 |
SLC6A11,SLC7A14,SLC32A1,SLC6A8,SLC6A12,SLC6A6,SLC6A1,NHERF1 |
| 4.229e-04 | -7.77 | IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | REACTOME pathways | R-HSA-975163 | 16 | 12 | 10285 | 3229 |
TAB2,TICAM2,TLR3,TRAF6,TAB1,CD14,TICAM1,LY96,RPS27A,UBA52,TLR4,UBB |
| 4.233e-04 | -7.77 | SHARPIN (SHANK associated RH domain interactor) | protein interactions | 81858 | 181 | 72 | 19454 | 5460 |
BCL10,IKBKB,TIAM1,PSMD7,TRAF6,TSNAX,WDR11,SPATA2,CTNNB1,TENM3,MIOS,SPPL3,MDM2,RTL6,DECR2,WDR82,CSRNP1,TLR3,MOXD1,ACTR2,TAB2,OTULIN,UBL4A,PPIL3,GCHFR,PSMA1,ZNF609,TNF,RBCK1,ADIPOQ,PSMD12,RAB18,LTBR,SLC25A11,RPL23A,DNAJB4,RABGGTB,BAG2,EPHA2,OSGEP,CBR3,TNFAIP3,LMO2,PSMB2,PSMA4,LDHB,CUL3,TAB1,APEX1,TRAF1,ZNF507,STUB1,FAM91A1,PSMA6,PRMT5,PTEN,WRAP53,LARP4B,PSMC4,PSMB3,NEK7,PHB2,NANP,PRIM2,CWF19L1,TXNL1,HSPA8,ARPC2,PSMA3,ITGA2,RAB9A,GPX4 |
| 4.240e-04 | -7.77 | GOLGA5 (golgin A5) | protein interactions | 9950 | 214 | 83 | 19454 | 5460 |
PTAR1,BET1,CDC42,SEC62,OTULINL,RND2,P2RY12,FGFR1,GPR35,GOLGA5,GIT2,ARL15,NCDN,PEBP1,XRCC5,TSPAN15,TACR1,RAB9A,RAB5A,KDM1A,GABBR1,LPAR1,OIP5,STX7,PXMP2,KDSR,RAB2A,GPR17,RAB11A,DNAJC5,LAMTOR1,BRCA1,CCHCR1,CD79B,S1PR4,ARF1,SCAMP2,SYNGR1,PHF21A,GPR173,B4GALT3,ESR2,KBTBD4,MAX,YIPF3,RAB4A,CYB5B,TFPT,RAB1A,TMT1A,ATP5PF,SLC2A8,LPAR2,ARL5B,RAB3B,ARF4,SAR1B,LAMP2,TSPAN10,RAB5C,CCR6,LAMP3,EXOC1,RHOG,RPRD1A,RAB35,HSD17B11,ADAM21,GJA1,SPINT2,RAC2,RAB1B,OCRL,ARF6,CD151,TNFSF18,RHOH,TMPO,STX6,NUP35,CAV1,HMG20A,NUF2 |
| 4.246e-04 | -7.76 | TERT (telomerase reverse transcriptase) | protein interactions | 7015 | 111 | 48 | 19454 | 5460 |
ACAA2,MET,DYRK2,PRKCA,NF2,SOX3,UBE2D3,PML,XRCC5,TERT,SMG5,YWHAZ,HSP90AA1,SLC7A11,STK11,AKT1,MYC,DYNLL1,TIMM21,ATP5F1B,APEX1,SRC,IREB2,ENO1,TUBA1B,STUB1,TP53,CDK4,CCT5,RAF1,MAP2K3,RUVBL1,TGFBR2,PTGES3,PFDN1,PABPC1,RUVBL2,HAPSTR1,BECN1,TERC,XPO1,GRM1,EIF2S1,FZR1,DKC1,MDM2,PPIA,CDK6 |
| 4.249e-04 | -7.76 | NIPBL (NIPBL cohesin loading factor) | protein interactions | 25836 | 184 | 73 | 19454 | 5460 |
STK38L,HNF1B,MYC,TOMM40,PRPF31,NONO,AR,LMNB1,BRCA1,HSP90AA1,RIT1,ZNF330,PRMT5,SPINDOC,CBX5,RPL10,ESR2,VIRMA,APEX1,FAXC,LMNA,RPA2,KLF3,MED23,PPT1,PRSS23,PAX9,RPA3,SIRT7,HSPA8,SF3B1,MED13L,SQSTM1,NFIL3,STAU1,STK38,COIL,AZGP1,IRF4,GAPDH,KPNA1,BRD3,CTDSPL2,EED,CDK6,TOP1,SUMO2,CDC5L,ARFGAP1,HINFP,SUPT5H,EEF1A1,SOX2,H2AX,EGR2,CBX3,CDK8,SNIP1,RUVBL2,EWSR1,PCNA,DHX9,GPSM3,H3C1,KRAS,RUVBL1,HNRNPK,THRAP3,SSRP1,PAX6,POLDIP3,TFG,RAD21 |
| 4.255e-04 | -7.76 | ATG12 (autophagy related 12) | protein interactions | 9140 | 83 | 38 | 19454 | 5460 |
ATP5F1B,RAB33A,SH3BGRL,CAV1,NDUFAF4,ESR2,RPL32,MCL1,RPS12,ATG3,PSMD10,RB1CC1,EPHA2,SNX5,MDFI,KXD1,ATG7,XPO1,ATG101,EMC8,SERTAD1,PHB2,GABARAP,MAP1B,PLSCR1,SERTAD2,SF3B1,MAVS,RAB33B,SNAP23,SLC12A2,IER2,NLRP6,BIRC5,HGS,ATG16L1,SF3A1,MAP1LC3B |
| 4.255e-04 | -7.76 | CHST8 (carbohydrate sulfotransferase 8) | protein interactions | 64377 | 83 | 38 | 19454 | 5460 |
TOR3A,CLSTN3,FUT8,TMEM59,SEC62,EDEM3,MOXD1,PTRH2,FAM3C,TMEM160,FSTL1,RBM23,TMED1,SLC39A7,TAPBP,TMX3,GAL3ST1,GALNT12,CHCHD2,ERLEC1,TMED3,EDEM2,HSPA5,TMED5,TMED4,CNTNAP1,TMBIM6,RBM27,CALU,ARL10,YBEY,LRRC1,STX10,TMED9,NDUFS8,SELENON,OS9,NOP9 |
| 4.255e-04 | -7.76 | THOC6 (THO complex subunit 6) | protein interactions | 79228 | 83 | 38 | 19454 | 5460 |
ZC3H15,SSRP1,KRAS,HNRNPA0,STAU1,NMRAL1,RPA3,DDX39B,THOC3,SNRPA,HECTD1,RHOBTB1,RNF8,OTULIN,RPA2,CHMP4C,ZNF326,PPP2R1A,RAF1,SF3A1,ATG16L1,SRSF10,ESR2,THOC1,PTEN,CCNF,THOC2,SF3B6,VDAC2,ALYREF,ID1,BRD3,UBE2H,BRCA1,SNRNP70,SNRPB,LAMP2,MYC |
| 4.262e-04 | -7.76 | MAP2K7 (mitogen-activated protein kinase kinase 7) | protein interactions | 5609 | 187 | 74 | 19454 | 5460 |
LAMP3,XPO1,RAB5C,PPP3CA,AHSA1,AKAP8L,HAX1,FKBP4,TRAF6,AK2,TUBG1,BCL10,EEF1AKMT3,ACSL4,SDHB,AIP,WDR6,HSP90AB1,CDC5L,MRPS23,ILVBL,ATP5PD,CACYBP,PPP3R2,JUN,YTHDF2,MRPL49,NDUFS3,TNFAIP8L1,RTCB,SLC39A7,ERG28,CLPB,NDUFA4,MAP3K11,MAP1B,FKBP8,DUSP19,PTGES3,DMPK,GTF3C3,HSPE1,ANAPC11,ST13,MRPL16,CUL3,ATF4,MYC,TRIB1,PFDN6,CALU,HSP90AA1,ATP1A1,GADD45B,DNAJC10,SDF2L1,PRMT5,STUB1,MAP3K3,DUSP22,CDKN1A,CNP,PGRMC1,LPXN,SEC22B,ATG16L1,MAP3K12,ATP5PO,FTL,FABP4,ZDHHC17,TACR3,HSCB,CYFIP2 |
| 4.263e-04 | -7.76 | CLPB (ClpB family mitochondrial disaggregase) | protein interactions | 81570 | 208 | 81 | 19454 | 5460 |
NDUFA5,SAMM50,PAK5,MRPS34,TIMM29,DUSP22,TIMM13,DHRS4,MTX2,COQ8B,MRPS7,PHB2,STAU1,SLC25A51,UCHL3,ARFIP1,EP300,HSPA8,TIMP3,MAIP1,HTRA2,ICA1,PPTC7,KIAA1191,CEP70,CUL3,CDKN3,COX6B1,APEX1,PARL,VIRMA,ESR2,CHCHD3,PTPMT1,DLST,CCNF,FAM136A,NDUFS3,HDAC11,HOXB1,APOO,E2F4,TP53,RAF1,IMMP2L,FASTKD5,DUSP21,DNAJC30,USP30,TRIM11,OPA3,SFXN1,NDUFA4,PALM2AKAP2,PEX3,MRPS26,HAX1,SMAD9,DNAJC4,TRAPPC2L,SNRNP70,SLC25A28,RHOG,XPO1,MRPS35,MDFI,RMND1,COX14,PLGRKT,SLC25A12,EGLN3,MDM2,NDUFS8,SPPL3,FBXO32,COQ10B,COX4I1,NAP1L5,AIFM1,MRPS9,COQ8A |
| 4.273e-04 | -7.76 | FDFT1 (farnesyl-diphosphate farnesyltransferase 1) | protein interactions | 2222 | 134 | 56 | 19454 | 5460 |
LMBR1L,CCNF,ELOVL4,SEC61B,TENT5C,APLNR,ESR2,CREB3,GPR17,CUL3,SYP,DCAF4,NRP1,BAP1,TMX2,JAGN1,RPA3,PML,VIPR1,SYVN1,HSPA8,DERL1,SEC62,OTULINL,ST7,RPA2,LMNA,SSR1,HEXIM1,CHRNB2,HRAS,COQ8A,CD274,DUSP6,LDLR,SHPRH,EGLN3,TLCD4,FAM20C,RB1CC1,RFLNA,TMT1A,TAS1R2,LPAR2,RUVBL2,G3BP1,SRPRB,RUVBL1,IMMP2L,CCDC47,UBL4A,RPN1,SMNDC1,ITGB5,POMT2,PLD3 |
| 4.273e-04 | -7.76 | CNOT7 (CCR4-NOT transcription complex subunit 7) | protein interactions | 29883 | 134 | 56 | 19454 | 5460 |
CEP85,BAG3,FBXO7,FBXW11,GADD45B,RC3H2,UHMK1,CNOT6,FANCD2OS,BTG3,DYRK1A,NMI,ESR2,PRRC2A,AGO1,BTG2,TCP11L1,CDK1,SH3GLB2,HCFC2,SMG5,YTHDF1,B9D2,PIAS1,PSMC1,FOXC2,CNOT2,NFKB1,XPO1,CNOT8,CPEB1,LSM3,CBL,CDK6,TSG101,EGLN3,CNTROB,YTHDF2,CDK4,TNRC6C,MACO1,TOP3B,SOCS3,CAPZA2,APEH,BTG1,GPBP1L1,GARRE1,PABPC1,MRFAP1L1,FHL3,ZC3H7A,CAPZA1,TOB2,PSEN1,CNOT6L |
| 4.273e-04 | -7.76 | OMA1 (OMA1 zinc metallopeptidase) | protein interactions | 115209 | 134 | 56 | 19454 | 5460 |
ATP1A1,TBC1D25,SYCE3,NDUFB10,SCN3B,MCM3,CHCHD3,NDUFAF4,PARL,GXYLT1,CHCHD6,COX6C,SAMM50,FAM8A1,CYC1,CNPPD1,TIMMDC1,MTX2,TIMM13,NDUFS2,EMC1,SLC25A51,SLC15A1,TMEM126B,AK2,NCR3LG1,HAX1,COX5A,EDEM1,NDUFV2,ATP1B1,TOMM70,OPRL1,SLC25A12,PLGRKT,AIFM1,OCIAD2,COX4I1,GPD2,BZW2,SLC4A8,FAM136A,NDUFA12,VAC14,SLC25A24,TOR3A,FAM162A,APOO,TIMM8A,USP30,UST,EDEM2,IMMP2L,NDUFB5,SFXN1,CLPB |
| 4.277e-04 | -7.76 | PYCR2 (pyrroline-5-carboxylate reductase 2) | protein interactions | 29920 | 193 | 76 | 19454 | 5460 |
COX14,RMND1,RAMP3,COX4I1,AIFM1,SSBP1,GATD3,SHC1,CHCHD1,TMEM70,RHOG,MRPS26,DNAJC7,CDC23,DNAJC4,MTRF1,HMGA1,GRSF1,DNAJC30,G3BP1,IMMP2L,MDC1,PRDX4,FASTKD5,SFXN1,HSPD1,NUDT5,COX8A,SKA1,HINT2,PDHA1,SKA3,EZH2,RNF8,GFM2,MRPL11,METTL15,AURKAIP1,PARL,ESR2,CCDC90B,DLST,CCNF,IRF2,TACO1,ANAPC2,RC3H2,HTRA2,DNAJC19,ANAPC4,PMPCA,CUL3,PYCR1,AUH,MYC,MTG2,CDC16,PCCB,TUFM,NUCKS1,FBXW7,FXR2,NF2,HSCB,CRYZ,NT5C3A,EXD2,NGRN,BAP1,GFM1,EP300,NMRAL1,ANAPC16,MTRES1,KCND3,DUSP14 |
| 4.280e-04 | -7.76 | NUP107 (nucleoporin 107) | protein interactions | 57122 | 199 | 78 | 19454 | 5460 |
NUP37,NUP153,E2F4,RANBP1,RAF1,COMTD1,NUPR1,PTRH2,PDHA1,EZH2,STIM1,VPS33A,GLE1,SIGLECL1,RPN1,COX8A,FKBP8,NUP42,KRAS,GAPDH,XPO1,SLC25A46,IFI16,KRT8,NXT1,EED,RCHY1,FBXO32,CD274,PTPN1,HSP90AB1,NUP35,CDC5L,TMPO,EGLN3,CDK9,SUMO2,DNAJC1,SUMO1,NUP62,ATG16L1,EIF4B,RPA2,LMNA,NUP50,DERL1,SIRT7,RPA3,TMEM209,TOMM20,FBXW7,B9D2,KDM1A,PSMD1,CUL3,PYCARD,FOXA3,SEC13,MYC,MAPRE1,XPOT,ATP1A1,H2AZ2,BRCA1,BICD2,LMNB1,SEC61B,ANAPC2,UBE2I,PHF21A,SEC61A1,FOXP3,RAN,LMBR1L,CD1E,VIRMA,DYRK1A,MGST3 |
| 4.336e-04 | -7.74 | positive regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001244 | 64 | 32 | 18204 | 5365 |
BECN1,FBXW7,NKX3-1,NACC2,S100A8,RPS7,FIS1,RPL26,SOD1,DDIT3,PLEKHF1,MIR186,MCL1,MYC,PMAIP1,BAX,MIR16-1,PRKRA,MSX1,FLCN,BAD,NUPR1,UBB,NCK1,RPS3,MIR15A,NHERF1,CAV1,SERINC3,TP53,BOK,SIAH1 |
| 4.341e-04 | -7.74 | AP2A1 (adaptor related protein complex 2 subunit alpha 1) | protein interactions | 160 | 269 | 101 | 19454 | 5460 |
ZCCHC10,ATG9A,LAMP2,DDRGK1,INSYN1,XPO1,AGR2,MED4,SMAD9,DNM2,MAP1LC3A,OCRL,E2F4,TOP3B,ARFGAP1,RAF1,ISG15,TRAF2,EZH2,AP2S1,GPBP1L1,GHR,HNRNPA2B1,CCDC32,UTP25,MYC,BTF3,MYO6,BRCA1,LAMTOR1,RIT1,LMBR1L,AP2M1,ESR2,MAT2B,TANK,PPP1CB,EHD1,SOST,MED23,NKAPD1,BMPR1A,DDX39B,NUP50,EP300,SF3B1,HSPA8,ADRB2,HSCB,UFL1,RNF11,SPATS2L,HDAC6,ESYT1,SHC1,BRD3,PRNP,ARF6,KCTD15,TMPO,STX6,TNRC6C,SNAP29,NECAP2,MAP1LC3B,NECAP1,CAPZA2,TFRC,SGIP1,NUPR1,FURIN,RNF8,ERO1A,L1CAM,TOLLIP,CCNB1,DNAJC5,PPP1CC,TXNIP,RC3H2,UBE2H,NRP1,EPHA2,SMAP2,DEK,DYRK1A,VIRMA,CFTR,FGFR1,METTL14,PICALM,RPA2,STAMBP,HEXIM1,DVL2,BAP1,RPA3,DERL1,MTDH,MEA1,FBXW7 |
| 4.346e-04 | -7.74 | MAPK family signaling cascades | REACTOME pathways | R-HSA-5683057 | 290 | 118 | 10285 | 3229 |
FRS3,PSMD10,DUSP9,SRC,MOV10,FGF10,RAP1B,KRAS,MAP2K1,WDR83,FGF22,UBA52,TNRC6C,RAF1,IL2RG,YWHAB,CDC42,FGF1,PPP2R5A,DUSP6,PAQR3,MET,PSMA5,FGF23,PPP2R5E,SPTAN1,PEBP1,PSMB3,SHC1,RASGRP3,PSMB4,PAK2,SEM1,CCND3,DUSP1,PSMC3,PSMA1,RPS27A,IL3,CDC42EP3,PHB1,PSMD4,SPRED1,FGF16,LAMTOR3,CAMK2G,IL2RB,VWF,CUL3,PSMC1,IL5,PPP2CB,KIT,LAMTOR2,HRAS,PSMB2,PSMD1,HSPB1,PEA15,PSMA6,RAG1,AGO1,PPP5C,SPTBN1,PSME1,ANGPT1,CDK1,FGF17,PSMD7,PSMD14,PTPN11,PRKACB,PPP2R1A,IGF2BP1,UBB,PSMB7,JAK2,PSMD3,CDC42EP2,PSMB1,IL6,PSMB5,PSMA3,PSMC4,PSMA4,PSMB10,PSMB11,JUN,PSMC5,FGFR1,IL2,PSMA2,PSMB6,CSK,BRAP,DLG4,PSME2,FGF3,HBEGF,MAPKAPK5,PSMD6,SPRED2,IL2RA,PSMB9,MAP3K11,DUSP10,NEFL,CSF2,JAK1,FGF7,SEPTIN7,MYC,MAPK4,PSMD12,SHC3,XPO1,RAP1A,IL6ST |
| 4.359e-04 | -7.74 | Diseases of signal transduction | REACTOME pathways | R-HSA-5663202 | 369 | 146 | 10285 | 3229 |
PSMB11,PSMC5,FGFR1,PSMB10,PSMA4,SMAD2,CD28,TNKS,CSK,BRAP,PSMB6,PSMA2,PIK3R1,OS9,PSMB1,CREB1,PSMD3,JAK2,PSMB7,CDKN1B,PSMC4,PSMB5,AGTRAP,PSMA3,TTR,PTPN11,PSMD14,DERL2,POLR2F,SYVN1,UBB,STAT5A,CBL,PPP2R1A,POLR2L,POLR2D,RBPJ,FKBP1A,CTBP1,SKP1,PSEN2,PSME1,FGFR1OP2,FZD4,TRIM24,PSMD7,CD80,ZMYM2,FGF17,NCSTN,AKT2,RAP1A,CSNK1A1,STAT1,POLR2I,GTF2F1,CDKN1A,PIK3R3,HDAC5,PSMD12,MYC,FGF7,GSK3A,MAP3K11,BAD,AGK,PSMD6,HBEGF,FGF3,PSME2,FBXW7,TNKS2,PSMB9,HDAC11,FGF23,PSMA5,MET,PEBP1,APH1A,PSMB3,PPP2R5E,ICOS,DKK1,PIK3R2,ERLEC1,FGF1,PPP2R5A,MDM2,TENT4A,YWHAB,MAP2K1,SMAD3,GTF2F2,KRAS,POLR2G,RAP1B,RAF1,ATG7,TGFBR2,FGF22,UBA52,LMNA,AGGF1,SRC,PSMD10,POLR2B,EP300,FGF10,PIK3AP1,POLR2C,PPP2CB,KIT,HRAS,GAB1,HEY2,HSP90AA1,PIK3CA,AKT1,PSMA6,AKT3,PSMD1,PSMB2,HDAC6,CLCN6,CDK8,FGF16,PSENEN,CREBBP,FZD6,PSMC1,VWF,SMAD4,CD86,PSMA1,PSMC3,CTNNB1,PSMD4,PHB1,ERLIN2,RPS27A,PSMB4,SHC1,NCBP2,LRP6,HDAC3,SEM1 |
| 4.370e-04 | -7.74 | response to progesterone | biological process | GO:0032570 | 44 | 24 | 18204 | 5365 |
TGFB2,GAD2,WBP2,TXNIP,UBE3A,ABHD2,CAV1,FOS,TYMS,OXTR,GJB2,PTGER2,IGF1R,CLDN4,SRC,TLR2,TACR1,HSPA8,CYP1B1,TGFB3,ERRFI1,TSPO,CD38,VPS54 |
| 4.370e-04 | -7.74 | regulation of release of cytochrome c from mitochondria | biological process | GO:0090199 | 44 | 24 | 18204 | 5365 |
BAK1,PMAIP1,BAX,FXN,PPIF,GPX1,PARL,MMP9,GHITM,PYCARD,BAD,TNFSF10,FAM162A,CLU,LMNA,IGF1,BCL2L1,PSMD10,PLSCR3,PDCD5,TP53,PRELID1,AKT1,MLLT11 |
| 4.370e-04 | -7.74 | negative regulation of interleukin-1 beta production | biological process | GO:0032691 | 44 | 24 | 18204 | 5365 |
GHRL,MIR181D,MIR132,NLRP3,MIR98,LILRB4,CPTP,IGF1,RAD21,MIR708,CX3CL1,MIR101-1,ACP5,MIR204,PML,SERPINB1,CX3CR1,MIR920,GSTP1,TNFAIP3,MIR195,MIR877,PYDC2,MIR488 |
| 4.372e-04 | -7.74 | G beta:gamma signalling through PLC beta | REACTOME pathways | R-HSA-418217 | 20 | 14 | 10285 | 3229 |
GNG10,GNG7,GNB3,GNB4,GNGT2,GNG5,PLCB1,GNG11,GNG3,GNG2,PLCB2,GNG12,GNB1,GNG13 |
| 4.377e-04 | -7.73 | transcription by RNA polymerase II | biological process | GO:0006366 | 391 | 146 | 18204 | 5365 |
RPRD1B,ELOC,MED23,VDR,SNAPC1,MED9,MSX1,TAF9,TRMT112,CTNNB1,GTF2H5,SIRT7,SKIC8,TCEA1,GTF2B,DPY30,ENY2,EP300,DR1,SMAD4,MED22,ADRB2,ZNF345,GTF2A2,PROX1,APOBEC3C,PRDM4,SGF29,PKNOX1,S100A10,EAF2,MED11,FOXA3,MED30,PIR,MED10,PLAC8,BCL6,SSU72,OGG1,RPRD1A,RB1,SUPT3H,GTF2E2,NFKB1,KPNA6,MACROH2A1,WBP2,NR1H2,CDK9,POLR2B,SPHK2,MED4,TAF11,JAK2,FOS,MED31,SMAD1,TFCP2,SUPT5H,NFYA,SNAPC5,AR,TRIM24,CDK7,IL2,CYTL1,CDK12,SART3,LDB1,SOX9,NDP,CCNH,SUB1,XBP1,APOBEC3A,PADI2,NCBP2,ADRM1,SUPT4H1,CREB1,ELOF1,GTF2F1,VPS72,EPOP,MED17,TP53,APEX1,WWP2,POLR2C,ERCC3,TAF7,NKX3-2,TAF10,SQSTM1,POLR2G,ATF4,POLR2F,NFIL3,MED21,BARX2,USP15,GTF2F2,KLF4,POLR2D,FOXP3,HELT,COPS2,GTF2H2,ATXN1L,TCEA2,GTF2I,GTF2A1,NCAPG2,MED27,CD28,CBFB,DRAP1,SMARCB1,BCL9,WNT10B,EGR1,MED29,PAX6,POLR2L,MNAT1,SNAPC3,NR4A2,GTF2E1,CDC73,PPARG,NIBAN2,SNAPC2,POLR2I,DEK,APOBEC3F,TAF5L,IRF1,GTF2H4,TAF2,PAAF1,IRF9,HDAC3,ZMPSTE24,PIK3R1,GTF2IRD1 |
| 4.380e-04 | -7.73 | TMEM165 (transmembrane protein 165) | protein interactions | 55858 | 97 | 43 | 19454 | 5460 |
STX5,LDLR,SLC1A1,RPLP1,LMBR1L,HRAS,CCNF,COX4I1,PHB1,EGLN3,VIRMA,ESR2,SPPL3,GORASP2,CNOT2,RAB2A,DPP4,FAM20C,CUL3,RAB5C,RPS26,RNF139,STYK1,CALU,ILK,NMRAL1,ARPC2,ATP2C1,RPA3,PDE2A,RIGI,KRAS,SLC35E1,CFTR,ERRFI1,PTAR1,B3GALT4,COQ8B,TP53,PPME1,CYB5B,CDK1,RPA2 |
| 4.380e-04 | -7.73 | SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2) | protein interactions | 56904 | 97 | 43 | 19454 | 5460 |
TSG101,PRMT5,GADD45G,APEX1,NMI,TRAF1,YES1,NTAQ1,CFL2,GTF2E1,TPM3,STK4,RSPH1,CDKN2D,GMPPB,MORF4L1,MED4,LSM3,EXOSC1,CALU,CRTAP,FKBP4,EFHC1,PGK1,PICK1,HSPA8,THG1L,PSMA3,FHL3,MAVS,PRKD3,CCND3,CNOT7,KDM1A,LZTFL1,CDC42,EEF1A1,LNX2,GIT2,SH3GLB2,SH3GLB1,VPS33A,PICALM |
| 4.380e-04 | -7.73 | CHMP1A (charged multivesicular body protein 1A) | protein interactions | 5119 | 97 | 43 | 19454 | 5460 |
ATP5PB,RAF1,MAX,DDIT4L,MND1,CFTR,GPX7,SDCBP,VPS4B,CHMP1A,STAMBP,HNRNPA2B1,PSMA1,CHMP1B,NF2,USP8,CHMP2B,PSEN1,ZDHHC17,MRPS18C,VTA1,UNC45A,TFG,MOV10,RAB5C,WWP2,BTF3,GORASP2,ANKRD49,MECP2,VPS4A,EZH1,HEY2,UBE2I,YES1,CGAS,CHMP5,TAX1BP1,NR1I2,POLE3,ZBTB2,ESR2,CHMP2A |
| 4.380e-04 | -7.73 | TYMS (thymidylate synthetase) | protein interactions | 7298 | 97 | 43 | 19454 | 5460 |
UBE2M,RPA2,LMNA,VPS4B,CDC42,DET1,ATP6V1C1,PKIG,NAPG,RNF5,UBE2K,NF2,RPA3,TXNDC17,MARCHF3,STK11,PFDN2,BFAR,TXN,RPGRIP1L,PPAT,PTEN,EFHD2,ZRANB2,MOB3C,PLS3,UBE2B,TP53,E2F4,UBE2A,PFDN1,AHCYL1,REXO2,KRAS,PSMA5,POC1B,PABPC1,PGAM1,MARCHF4,TYMS,IGBP1,DCK,PHB1 |
| 4.380e-04 | -7.73 | RBM15B (RNA binding motif protein 15B) | protein interactions | 29890 | 97 | 43 | 19454 | 5460 |
TMEM14B,WTAP,NUFIP2,TOX4,DDX42,ISG15,EGR2,ATG16L1,RAF1,WDR83,MEPCE,PSENEN,SEM1,FAM76B,SNIP1,ANKRD50,UQCR11,CDC23,NCKIPSD,SNRNP70,TRIM23,KLHL22,HNRNPA1,YWHAG,ANAPC15,PPIL4,YWHAH,CIAO1,MYC,VIRMA,SRPK2,DHX15,ESR2,CDK9,PPP1R10,THOC1,MATR3,TRIM54,WDR82,SF3B4,ALYREF,CTTN,EZH1 |
| 4.384e-04 | -7.73 | DNAJC1 (DnaJ heat shock protein family (Hsp40) member C1) | protein interactions | 64215 | 356 | 129 | 19454 | 5460 |
C9orf72,RPL7A,HMOX2,ZNF622,RPL13A,SEC63,GANAB,SRP54,LMNA,STOM,USE1,SSR1,SLC12A2,TMX4,RPLP0,PDCL,LEMD3,RABL3,SEC22B,ARHGAP1,PLP2,CFTR,ST7,YKT6,RPL4,ZC3H15,TMEM209,HSPA5,PPM1G,TEX264,RPL27,MTDH,RTN4,DERL1,MED29,ECD,ESYT1,RPL10A,OSBPL8,TMEM199,EMC4,DHRS7,HM13,ARL6IP5,LMAN1,POLE3,TMPO,RPL12,PTPN1,SRPRA,CAMLG,RWDD1,HSD17B11,RAC2,SURF4,PREB,CCDC47,LBR,RPL15,NUP107,RAB3B,SRPRB,FKBP8,RPL3,STX18,EMC2,SPCS3,LMNB1,SCFD1,VEZT,REEP4,CHCHD3,ESR2,ATP6AP2,TMCC1,RPL37A,SEC61B,VAPB,MAP2K1,CMTM7,PGRMC1,AGTRAP,NOTCH2,TOR1AIP2,OTULINL,SEC62,EMC1,UFL1,PXMP2,CMAS,DNAJC3,HSPA8,HADHA,CDK5RAP3,DRG2,DRG1,LAMP2,WWP2,RPL6,RAB5C,PTDSS1,DDRGK1,RPL7,SLMAP,RMND1,RPL8,RPL9,RPLP2,STX5,STIM1,RPN1,AQP3,TAPT1,PLD3,RPL18,STBD1,MACO1,EMC10,DNAJC25,SERPINA3,FAF2,MSX2,EMC8,KRAS,RPL28,RETREG1,CYP2C9,RINT1,TMT1A |
| 4.384e-04 | -7.73 | RAD50 (RAD50 double strand break repair protein) | protein interactions | 10111 | 356 | 129 | 19454 | 5460 |
GTF2I,KDM1A,HMGB1,FBXW7,GABARAP,HSPA5,RPA3,BAP1,PML,SIRT7,NBN,TRIM10,PPIH,LMNA,RPA2,RPGRIP1L,DUSP10,VIRMA,CCNF,DCLRE1C,MOB4,RPS20,MSN,CHCHD4,UBE2H,CSK,NONO,AR,H3C1,DYNC1I1,VRK1,PHF1,RNF20,MDC1,MSH6,RIGI,CAPZA1,CTSC,LIPA,CHAMP1,NECAP1,ILF2,RNF8,ZFAND2A,TP53,CCT5,H2AX,PLEKHF2,MDM2,RAB39B,CDC5L,PTPN1,EEF1AKMT3,PREP,TLE1,HDAC6,ZFAND2B,STAU1,MCMBP,RFC4,XRCC5,HSPA8,HDAC5,EP300,DDX5,PPARG,MED23,RNF7,EIF4B,PIH1D1,MTMR6,INSYN2A,PPP1CB,RFXANK,MATR3,DYNLL1,BMP1,TSN,SYNE4,TRIM29,ACTB,ESR2,CRYBB3,DLST,ZMYM2,PHF21A,RBBP8,MCM8,BRCA1,HSP90AA1,COP1,MAF1,FAM219A,CREBBP,MYC,CUL3,BTF3,RNF40,CFAP161,MCM3,PELI1,KRAS,CDK20,CCT8,TOP2B,RINT1,RPAP3,ZC3H7A,EZH2,POLR2C,NLRP2,RNF126,ZNF263,E2F4,NCSTN,ZNF511,OSBP,SNX1,SUMO2,EGLN3,CCT7,EED,PSMD10,NCK1,DDX1,YWHAB,UBXN6,NDC80,HNRNPA1 |
| 4.391e-04 | -7.73 | autophagosome assembly | biological process | GO:0000045 | 77 | 37 | 18204 | 5365 |
ATG3,STBD1,ATG16L1,ATG4A,RAB23,TOM1,RAB33B,ATG101,RAB33A,UBXN2B,TP53INP2,MAP1LC3A,VMP1,RAB1A,GABARAPL1,TP53INP1,MAP1LC3B,NSFL1C,STX12,TRAF6,BAG3,EMC6,RAB1B,SMURF1,RB1CC1,GABARAPL2,ATG7,ATG9A,MTM1,ATG4C,PSEN1,WDR45,RAB19,CTSD,STX17,GABARAP,BECN1 |
| 4.391e-04 | -7.73 | protein K48-linked ubiquitination | biological process | GO:0070936 | 77 | 37 | 18204 | 5365 |
RNF8,SKP1,RNF5,TOPORS,UBE2A,PELI1,TRIM21,RNF34,UBE2D1,CUL3,UBE2G2,BFAR,ZNRF1,KLHL3,UBE2B,RNF187,TNFAIP3,TRIM45,TRIM32,SYVN1,RNF152,RNF126,TRIM6,UBE2D3,RNF115,KBTBD6,FBXO7,RNF146,UBE2E3,IFI27,UBE2H,NT5C2,UBE3A,NMI,FBXO9,UBE2K,UBE2E2 |
| 4.408e-04 | -7.73 | USP37 (ubiquitin specific peptidase 37) | protein interactions | 57695 | 114 | 49 | 19454 | 5460 |
CDC23,DPY30,CDC26,PRPF19,CTNNB1,YWHAG,CCAR2,FZR1,DHX15,H2AZ1,WDR82,CBX3,SF3B5,MAX,ANAPC13,TUBA1A,KRAS,RAD21,GTF3C3,MCM6,BRCA1,FBXW11,ANAPC4,CDC73,CCNB1,HNRNPC,CDC16,MYC,MCM4,ANAPC15,SNRNP40,VIRMA,CDC20,ALB,TRIM24,INTS12,ADNP,ZNF326,RPA2,CCNA2,PPP1CB,GTF3C4,GTF2I,SKP1,SAP18,PRIM2,RPA3,RHOU,ANAPC16 |
| 4.413e-04 | -7.73 | upper_aerodigestive_tract-pharynx-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma | 13 | 10 | 16828 | 4835 |
KIT,RB1,HRAS,CTNNB1,KRAS,TP53,JAK2,CDKN2C,PIK3CA,SF3B1 |
| 4.413e-04 | -7.73 | ovary-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-transitional_cell_carcinoma | 13 | 10 | 16828 | 4835 |
DICER1,PIK3CA,IDH1,IDH2,PPP2R1A,CREBBP,CTNNB1,KRAS,BRCA1,TP53 |
| 4.418e-04 | -7.72 | Interleukin-4 and 13 signaling | REACTOME pathways | R-HSA-6785807 | 111 | 52 | 10285 | 3229 |
IL12B,MMP9,CD36,CCND1,IL13,HSPA8,TNF,IL23A,SOCS5,CXCL8,IRF4,TIMP1,IL10,SOX2,BIRC5,IL6,FOS,JAK2,IL2RG,SOCS3,TNFRSF1B,PIK3R1,CCL2,IL1A,RHOU,IL17F,IL4,JUNB,FASLG,NDN,HSP90B1,BCL2L1,CCL11,VEGFA,OSM,OPRM1,TP53,IL1B,JAK1,MYC,BATF,COL1A2,MCL1,IL18,IL12A,CDKN1A,ICAM1,HSP90AA1,STAT1,AKT1,BCL6,STAT6 |
| 4.425e-04 | -7.72 | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | 15 | 11 | 16828 | 4835 |
TERT,SMARCB1,PTEN,TP53,HRAS,RB1,KRAS,IDH2,IDH1,NF2,AKT1 |
| 4.425e-04 | -7.72 | TM4SF5 (transmembrane 4 L six family member 5) | protein interactions | 9032 | 31 | 18 | 19454 | 5460 |
STX10,AMIGO1,RTN4,VAMP3,PLSCR1,HSDL1,ATL1,PXMP2,SLC25A17,CYSTM1,STX6,ARL6IP5,SLC31A1,LGALS3,FAM241A,NUS1,FAM241B,PTRH2 |
| 4.425e-04 | -7.72 | MAGEF1 (MAGE family member F1) | protein interactions | 64110 | 31 | 18 | 19454 | 5460 |
PHF7,EID1,SMCHD1,HDAC6,EID2,MAT2A,MDFI,PGRMC1,EID2B,FTL,PYGM,ECHDC1,FBXW7,TRIM27,RAP1B,LHFPL2,PPM1G,PPP1R12A |
| 4.425e-04 | -7.72 | MZF1 (myeloid zinc finger 1) | protein interactions | 7593 | 31 | 18 | 19454 | 5460 |
RNASEH1,APEX1,LDOC1,ZKSCAN1,ZNF174,STUB1,FHL3,CDK6,FBXO11,TWNK,SCAND1,NUDT12,CBL,CDK4,ZNF24,ZSCAN1,ZMYM4,LBR |
| 4.425e-04 | -7.72 | CCDC74B (coiled-coil domain containing 74B) | protein interactions | 91409 | 31 | 18 | 19454 | 5460 |
PSMC3,PSMD14,PSMD7,PSMD10,PSMD1,PSMC4,PSMD3,HENMT1,PSMC1,PSMD12,KDM1A,PSMD4,PSMD6,ADRM1,PSMC5,UBASH3B,THNSL1,SCNM1 |
| 4.455e-04 | -7.72 | RASSF5 (Ras association domain family member 5) | protein interactions | 83593 | 51 | 26 | 19454 | 5460 |
RALA,TRAF1,RABIF,STK3,MDM2,HRAS,MAP1LC3A,RRAS2,MRAS,RAP1B,SMAD4,SAV1,MAP1S,CIAO1,RAP2B,STK4,KRAS,VPS28,MAP1B,RAP2A,APPBP2,KCTD12,MYLIP,ATG16L1,TRAF2,MAP1LC3B |
| 4.455e-04 | -7.72 | PDK4 (pyruvate dehydrogenase kinase 4) | protein interactions | 5166 | 51 | 26 | 19454 | 5460 |
AIP,GYS1,POLR2B,HSP90AB1,CCT7,PLEKHF2,TCP1,XPO1,CNOT2,PFDN5,PYCR2,HSP90AA1,UHMK1,CCT2,AK2,DNAJC10,DLAT,CCT8,CNOT6L,PTGES3,CNOT7,NOP53,TRIM63,THRAP3,CCT5,PDHA1 |
| 4.455e-04 | -7.72 | TIRAP (TIR domain containing adaptor protein) | protein interactions | 114609 | 51 | 26 | 19454 | 5460 |
CAMK2G,IL1RAP,TICAM2,TICAM1,IRAK4,MYD88,DNAJC3,PIK3AP1,TLR4,KLHL24,JAK1,TLR2,PCNA,TAB2,CCDC47,DDX39A,TRAM1,TIRAP,TAB1,NTMT1,EIF2AK2,PRKRA,TRAF6,CD247,DHPS,SAMHD1 |
| 4.455e-04 | -7.72 | RAB3GAP2 (RAB3 GTPase activating non-catalytic protein subunit 2) | protein interactions | 25782 | 140 | 58 | 19454 | 5460 |
FEZ1,PTPN1,TES,MAP1LC3A,HSD17B11,PRNP,DNAJC1,LMAN1,PTP4A3,TMPO,RAB5C,SLC25A46,TSEN34,YWHAH,SHC1,ESYT1,SNRNP70,TMT1A,FKBP8,RIGI,MSH6,RBM12,TULP3,MAP1LC3B,DNAJC25,NUDCD3,STIM1,RPN1,CCNF,LMBR1L,SEC61B,GABPA,COPE,REEP3,SEC63,CUL3,CSK,FIS1,RPA3,BAP1,RAB5A,DERL1,RAB9A,SYVN1,STAU1,NUCKS1,KDM1A,PXMP2,CFTR,ST7,YIPF5,OTULINL,SEC62,SSR1,FGFR1,RPA2,VAPB,ACACA |
| 4.465e-04 | -7.71 | cellular response to oxidative stress | biological process | GO:0034599 | 228 | 91 | 18204 | 5365 |
STK26,MIRLET7B,AIF1,BECN1,PPIF,SOD1,CYP1B1,G6PD,CCS,MAP1LC3A,SLC25A24,EIF2S1,OGG1,CHCHD2,CRYGD,FOS,HDAC6,STAT6,PRR5L,TBC1D24,SELENOS,OSER1,RHOB,TMIGD1,TOP2B,GLRX2,PEX13,PYCR2,AIFM1,AKT1,PCNA,TXN,SLC1A1,GJB2,TNFAIP3,GPX1,IL18BP,RPS3,NUDT2,MT3,SLC7A11,PDCD10,ROMO1,SELENON,GPX5,FXN,HM13,ARL6IP5,VKORC1L1,STK24,RWDD1,HTRA2,NQO1,SESN2,CD36,PYCR1,SRXN1,EZH2,NFE2L2,SIN3A,NR4A2,EDNRA,CHCHD4,KLF4,GPR37L1,ATF4,PCGF2,PRDX2,JUN,PRDX1,GPX7,HSPA8,CDK1,SOD3,SRC,MPV17,STAU1,IL6,PRKRA,CYGB,TP53INP1,PRDX3,MIR34A,SOD2,MIR107,MMP9,DAPK1,PPIA,GPR37,MDM2,TP53 |
| 4.474e-04 | -7.71 | ADAM22 (ADAM metallopeptidase domain 22) | protein interactions | 53616 | 24 | 15 | 19454 | 5460 |
LGI1,DLG4,RAC2,TMEM74,GPIHBP1,KRAS,VIRMA,DYRK1A,EPS8,RAB2A,CSNK1E,YWHAZ,TUBB4B,HFE,YWHAB |
| 4.512e-04 | -7.70 | negative regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000134 | 85 | 40 | 18204 | 5365 |
PTEN,MIR137,MIR29C,MDM2,FBXO7,MIR638,CRLF3,CCL2,MIR133B,TP53,CDKN1A,CDK2AP2,PML,MIR16-1,CACNB4,CRADD,FBXO31,PRMT2,ZNF655,DCUN1D3,RB1,RPA2,EZH2,MIR15A,MIR29A,MIR193A,CDKN1B,FAM107A,ACVR1,GPNMB,KLF4,BTN2A2,CTDSP1,CCND1,DLG1,RPS27L,JADE1,RPL26,CTDSP2,CDC73 |
| 4.514e-04 | -7.70 | positive regulation of protein localization to nucleus | biological process | GO:1900182 | 93 | 43 | 18204 | 5365 |
LEP,CCT7,CREBBP,CCT8,STK11,HSP90AA1,DMAP1,CDK1,SRC,AKT1,ORMDL3,TRIM8,TFRC,HYAL2,EFCAB7,FERMT2,IFNG,SMAD3,EP300,DKC1,PSEN1,CCT5,F2,TCP1,JAK1,SESN2,JUP,BAG3,PIK3R2,HDAC3,PIK3R1,RAN,CD2AP,RBM22,TERT,CACNB4,TESK1,CDK5RAP3,MAVS,JAK2,HCLS1,MEPCE,CCT2 |
| 4.515e-04 | -7.70 | Parkinson's disease | KEGG pathways | hsa05012 | 129 | 63 | 7161 | 2463 |
VDAC2,NDUFC2,COX5A,PPIF,SDHB,UQCRC2,COX6B1,UBE2G2,DRD1,COX7B2,ATP5PB,NDUFB4,HTRA2,ATP5MC3,ATP5F1E,NDUFA2,ATP5PF,SLC25A31,UBE2L3,NDUFB10,CYC1,SLC25A5,UQCRH,NDUFB6,NDUFV2,PRKACB,ATP5F1D,SLC6A3,ATP5F1B,COX6C,NDUFA5,COX4I1,COX7A1,COX7B,NDUFA12,NDUFA4,NDUFB5,NDUFS6,COX8A,NDUFB8,GNAI2,VDAC1,NDUFAB1,SDHC,ATP5PO,ATP5PD,NDUFS3,SLC25A4,UBB,COX6A2,ATP5MC1,NDUFS2,ATP5F1A,UQCRQ,NDUFA1,NDUFB7,UQCR11,GNAI3,COX4I2,NDUFS8,UQCRC1,GPR37,COX6B2 |
| 4.527e-04 | -7.70 | PDLIM7 (PDZ and LIM domain 7) | protein interactions | 9260 | 257 | 97 | 19454 | 5460 |
RBCK1,PHF1,OLA1,PALM2AKAP2,TRAPPC1,ACOT13,CAPZA2,ARPC3,TAB2,TP53,IKZF5,GGCT,CDC5L,MDM2,MYL12A,TRAPPC3,TES,TRAPPC2L,SPP1,TRAPPC4,FNDC11,ZMYND11,TPM3,COPS5,FBXW7,SQSTM1,ARPC2,PRKCB,WWP1,METTL14,HBB,PAK5,PRKCA,TMOD1,LPXN,ATG16L1,SPTBN1,CFTR,YES1,RAB14,GARIN6,GNAI2,DYRK1A,RPP25,SMURF1,CTNNA1,CDPF1,CCNF,UBE2I,QSER1,HEY2,BICD2,ATOSB,CISD1,SORD,AP2A1,FAM163B,HNRNPF,ENKD1,ZYX,MYO1B,TNPO2,TRAF2,ACTN4,SPTAN1,ZNF576,EGLN3,ATP6V1A,TRAPPC10,TSG101,TRAF6,HNRNPD,WWP2,PTDSS1,ATG9A,CTNNB1,HSPB8,XPO1,STAU1,SPECC1L,RNF10,FRS3,MYL6,TCF19,ZCCHC7,DTD2,MB21D2,OTUD6A,ESR2,GNB1,SCNM1,AP2M1,RBBP8,CUL3,MYC,BAG3,BTF3 |
| 4.537e-04 | -7.70 | NVL (nuclear VCP like) | protein interactions | 4931 | 143 | 59 | 19454 | 5460 |
RPL18,NUPR1,ILF2,RBM34,CHMP4C,RPL15,MAK16,MAGEB10,RPL17,RPL28,VRK1,H1-6,KRAS,RPS24,RPL23A,RPL3,PPAN,RPL31,MPHOSPH6,HSPB1,DDX23,DDRGK1,NDUFV2,PLEKHO1,IFI16,MOV10,CEP19,ATP5PD,LYAR,SRP14,RPL26L1,RPLP0,APOBEC3C,RPS14,STAU1,FBXW7,RPL4,NPM3,DGCR8,UFL1,SIRT7,RPA3,RIT1,CRMP1,OSGEP,MECP2,AR,FBXO7,CUL3,RPL7A,MYC,RPL22,ESR2,RPL10,RPL13A,UBE2I,PRKRA,ZNF330,CCNF |
| 4.537e-04 | -7.70 | POLR2F (RNA polymerase II, I and III subunit F) | protein interactions | 5435 | 143 | 59 | 19454 | 5460 |
RPRD1A,GTF2B,POLR2L,POLR3F,POLR2I,WWP2,DNTTIP1,CSNK2A1,POLR3GL,MED21,MED27,MED29,MED4,PSME1,RPAP3,KRAS,DNAAF10,KPNA2,PDRG1,TRMT1L,SUPT5H,MED9,PSMB9,RPAP2,POLR2D,POLR2G,POLR2C,POLR3B,INTS10,GTF2F2,POLR3H,GTF2F1,INTS12,MED17,UBB,POLR2B,LRIF1,SRC,MYC,LMO2,RRN3,MED10,DCAF4,PFDN2,MAF1,PFDN6,POLR1B,RIT1,STAU1,POLR1H,INTS6L,POLR1D,MED30,SUPT4H1,SDC2,RPRD1B,IL15RA,GSTM2,PIH1D1 |
| 4.537e-04 | -7.70 | ATP13A3 (ATPase 13A3) | protein interactions | 79572 | 143 | 59 | 19454 | 5460 |
ORMDL3,LAMP3,P2RY10,CCR6,RAB5C,LAMP2,DOLK,RHOG,STARD3NL,RAC2,GJA1,AIFM1,HRAS,RAB35,TLCD4,UQCRH,ARF6,SPPL3,YIPF4,YIPF3,MGARP,TSPAN3,RAB4A,KRAS,SKAP2,ELOVL3,GPR17,RAB11A,RAB2A,ENTPD4,TMED5,LHFPL6,TYROBP,RHOB,LGALS8,LAMTOR1,GPR89A,GPR173,S1PR4,VIRMA,B4GAT1,VKORC1L1,SPCS1,LGALS3,RHOJ,KLRD1,HACD2,HCST,CDC42,BET1,TPRA1,GP9,GPR35,RAB5A,RAB9A,TSPAN15,PXMP2,STX7,RER1 |
| 4.541e-04 | -7.70 | IMPDH2 (inosine monophosphate dehydrogenase 2) | protein interactions | 3615 | 394 | 141 | 19454 | 5460 |
YWHAB,AHSA1,PSMD10,AGR2,CTNNB1,ATG7,PSMD3,DHX15,CETN2,EGLN3,SUMO2,SNX2,RPLP2,SWAP70,FOLR1,NME1,EZH2,SKA3,ANAPC13,GABARAPL1,JUN,TRAF2,SOX2,PPP2R1A,MAPK10,SLC25A44,MED9,PSMD12,VDAC1,HNRNPF,G3BP1,KRAS,BAG2,PCNA,CCT8,RIT1,BRCA1,PSMD14,BTF3,PSMD1,RNF40,SFN,CUL3,CUL2,MYC,RPL10,TENT5C,TSN,PSMD6,PSMD4,SNRPD2,DLST,ARF1,LMBR1L,EIF4B,ACAA2,KLF3,PPP1CB,STAU1,MCMBP,EMC1,UFL1,FXR2,UCHL3,NUP50,HSPA8,HDAC5,CRY1,DDX39B,DNAJC3,USP15,TSNAX,IGFBP4,MAP4,PSMD7,CRBN,API5,ELOC,HDAC6,PPIL4,COPS5,EMC4,NFKB1,NOP9,TES,COQ8A,AIFM1,PTPN1,NUPR1,TFCP2,RPL15,MAP1LC3B,INSIG2,SNAP29,MDC1,CAPZA1,FBXO25,RNF20,HNRNPK,TTC4,HUWE1,EMC2,FAF1,MAP1B,UBE2H,PTTG1,NAPA,USP14,GMPS,AKT1,VIRMA,UBB,ROCK1,ADRM1,PPAT,NDN,LDHA,RPS20,MSN,WDR45,PSMC5,CCNF,HECTD1,UBE2M,RPA2,CFTR,KLF12,CD2AP,PIP5K1A,ATG16L1,HSPA5,GTF2I,SQSTM1,PRKCB,CLK1,SIRT7,SOD1,RPA3,MME,SNAPC1,BAP1 |
| 4.544e-04 | -7.70 | TRIM7 (tripartite motif containing 7) | protein interactions | 81786 | 75 | 35 | 19454 | 5460 |
SRC,DES,MAD2L2,OTUD6A,SIAH1,RNF187,UBE2N,NABP1,HSP90AA1,BECN1,YWHAZ,GTF2A2,UBE2D1,BRMS1,ATG7,CFL2,NPTX1,IFI35,RAB2A,IRAK4,HSPA5,ADIPOQ,RNASE1,RPL4,UBE2D3,VPS26B,HSPA8,PRPSAP1,GLUL,PNMA2,MAP1LC3B,UBE2W,NAA35,TOP3B,H1-5 |
| 4.544e-04 | -7.70 | RELB (RELB proto-oncogene, NF-kB subunit) | protein interactions | 5971 | 75 | 35 | 19454 | 5460 |
SMARCB1,CDK1,EZH2,CBX3,DDX39A,COMMD8,ACTL6A,TOP3B,FBXW7,KPNA2,COMMD2,SMARCD3,CBL,SMAD2,KPNA1,SMAD4,COMMD9,MAP3K14,KPNA6,HDAC6,SMARCE1,COMMD5,XPO1,PSMA4,NFKB1,TAX1BP1,BUD31,TCEAL1,MTAP,MT1M,MAP1LC3A,NFKBIA,EEF1AKMT3,NFKBIB,SMAD3 |
| 4.544e-04 | -7.70 | MTCL1 (microtubule crosslinking factor 1) | protein interactions | 23255 | 75 | 35 | 19454 | 5460 |
FZR1,DYNLL1,PRNP,EGLN3,CDC5L,VIRMA,SRPK2,TUBA1B,EEF1AKMT3,GSK3A,KRT8,MYO6,YWHAB,MOV10,PPP2R5A,NDC80,YWHAG,YWHAH,SAMHD1,PPP2R2C,FBXW7,TOLLIP,RNF41,CAPZA1,HSPA5,NSDHL,CLK1,SQSTM1,PNMA2,CAPZA2,TRIM36,ATG16L1,ZNF263,WDR83,PPP2R1A |
| 4.545e-04 | -7.70 | oligodendrocyte development | biological process | GO:0014003 | 49 | 26 | 18204 | 5365 |
CLU,MIOS,TLR2,CNTN1,HDAC11,MOBP,TPPP,WASF3,B4GALT6,EIF2B5,CERS6,PTEN,GPM6B,LPAR1,MYRF,KCNJ10,ASPA,MECP2,NKX6-2,ID4,NCSTN,EIF2B3,EIF2B2,CNTNAP1,PLP1,FA2H |
| 4.561e-04 | -7.69 | HISTONEH2A | prints domains | PR00620 | 19 | 13 | 5227 | 1528 |
H2AB1,H2AX,H2AC7,H2AC4,MACROH2A2,H2AC1,MACROH2A1,H2AC14,H2AC25,H2AC6,H2AZ1,H2AZ2,H2AJ |
| 4.561e-04 | -7.69 | XBP1(S) activates chaperone genes | REACTOME pathways | R-HSA-381038 | 56 | 30 | 10285 | 3229 |
ARFGAP1,DNAJB9,CTDSP2,FKBP14,DNAJC3,SEC61A1,CXXC1,SULT1A3,XBP1,PLA2G4B,SRPRA,ADD1,SEC63,ZBTB17,SEC61B,SSR1,SEC61A2,GFPT1,SHC1,SEC61G,EDEM1,SEC62,YIF1A,GOSR2,PREB,GSK3A,SYVN1,PDIA6,LMNA,SRPRB |
| 4.562e-04 | -7.69 | KPNA5 (karyopherin subunit alpha 5) | protein interactions | 3841 | 86 | 39 | 19454 | 5460 |
ZRANB2,LMNA,ZNF326,ADNP,NUP153,CFTR,KBTBD4,ANP32A,MTA3,E2F4,MEPCE,ANP32B,H3C1,PHB2,SREK1IP1,NUP50,SPOPL,CDKN1B,KPNA1,TSEN54,SPOP,LMNB1,ATOSB,FBXO7,BRMS1,MYC,MOV10,HNRNPC,CUL3,ZBTB2,NOPCHAP1,VIRMA,SPPL3,MEAF6,LYAR,AIPL1,RBBP4,KLHL7,RAN |
| 4.562e-04 | -7.69 | GATB (glutamyl-tRNA amidotransferase subunit B) | protein interactions | 5188 | 117 | 50 | 19454 | 5460 |
MRPS11,COX8A,HINT2,HSPD1,IMMP2L,SNRPG,FASTKD5,PSMD12,RASL10B,TNFSF8,KRAS,MGARP,AURKAIP1,MRPL11,MRPL36,GATD3,FAHD1,SSBP1,CHMP2A,CD1A,MALSU1,KCTD10,CBR4,FAM174A,MTRF1,GRSF1,MRPS26,TMEM70,RHOG,GFM1,EXD2,AMACR,PSMC1,MRPL57,FBXW7,HSCB,MRPL12,MRPL10,MTRES1,TFB1M,QRSL1,MRPS28,CCDC90B,TACO1,MRPS21,TUFM,MRM2,PMPCA,AUH,MRPS25 |
| 4.562e-04 | -7.69 | SPCS3 (signal peptidase complex subunit 3) | protein interactions | 60559 | 117 | 50 | 19454 | 5460 |
PC,SEC11A,TMEM147,RUSF1,FKBP8,KRAS,TUBA1A,DNAJC25,DSTYK,RAF1,NEU1,DISC1,RAB6B,RAC2,TNIK,PTPN1,OS9,ANKRD46,DNAJC1,RAP2B,STK4,RHOG,MIA2,SPCS2,RPA3,TMEM106B,DNLZ,HSPA5,HSCB,GPC1,CDC42,OTULINL,ST7,PGRMC1,TCP11L1,VAPB,RPA2,GGT7,SFXN2,SEC61B,LMBR1L,RAN,CYB5R3,SEC63,ESR2,SPCS1,UFD1,MYC,RAP2C,SPOP |
| 4.578e-04 | -7.69 | electron transport chain | biological process | GO:0022900 | 112 | 50 | 18204 | 5365 |
NDUFB7,NDUFA5,NDUFA12,SDHAF2,CYB561,GPD2,UQCR11,NDUFB10,NDUFAB1,NDUFS8,NDUFA1,NDUFV2,ETFRF1,NDUFB6,UQCRC1,POR,COX6B1,SOD2,UQCC3,COX7B,IMMP2L,COX4I2,UQCRH,NDUFS2,COX6A2,COX4I1,VPS54,SDHB,UQCRQ,COX7A1,ETFA,NDUFB8,COX6C,SLC25A51,NDUFA2,SDHC,NDUFC2,SLC25A12,COX7B2,NDUFS6,NDUFA4,COX8A,TAFAZZIN,NDUFB5,NDUFS3,UQCRC2,NDUFB4,ETFB,COX5A,CYC1 |
| 4.594e-04 | -7.69 | G protein-coupled acetylcholine receptor signaling pathway | biological process | GO:0007213 | 21 | 14 | 18204 | 5365 |
GNA11,OPRM1,GNAQ,CDK5R1,CHRM4,PRKCB,CHRM3,HRH3,CHRM5,GNAI2,GNB1,RGS10,CHRM1,PLCB1 |
| 4.607e-04 | -7.68 | PAXBP1 (PAX3 and PAX7 binding protein 1) | protein interactions | 94104 | 100 | 44 | 19454 | 5460 |
DDX23,SNRNP70,KIAA1143,LSM3,MOV10,DDRGK1,MIRLET7G,SNRPA1,SNRPD3,EZH2,HDAC11,SNRPE,RAF1,JPH4,CD2BP2,TSSC4,KRAS,SRSF4,SNRPG,PQBP1,RC3H2,UBE2H,RIT1,MYC,SNRPB,AR,SNRNP40,SRPK2,ESR2,METAP2,GCFC2,RSRC1,RPA2,TFIP11,HECTD1,SF3A1,SNRPN,UFL1,TRA2B,NRBF2,RPA3,SNRPA,SF3B1,MIRLET7I |
| 4.607e-04 | -7.68 | Junb (jun B proto-oncogene) | protein interactions | 16477 | 100 | 44 | 19454 | 5460 |
CAV1,TRIR,SNRPA1,KCTD10,SYNCRIP,SRPRA,RBM5,BRD3,POLB,DDX23,FOSL2,MED29,KIAA1143,ECD,PPIL4,HNRNPA1,RBM17,CCAR1,FKBP8,TSSC4,TRIM21,ZC3H11A,TRIP4,HNRNPA2B1,MED9,SUPT5H,KIF1C,TNPO3,MED17,GTF2F2,GTPBP2,PNPO,CIRBP,DNAJC8,HNRNPA0,SF3B1,BIRC2,TNFAIP1,MFAP1,SDCBP,AGGF1,SF3A1,WDR77,EEF1E1 |
| 4.607e-04 | -7.68 | SYNE4 (spectrin repeat containing nuclear envelope family member 4) | protein interactions | 163183 | 100 | 44 | 19454 | 5460 |
CXCL9,VTI1B,TMEM248,CEP19,DEFB121,FZD3,EXT1,FAM241B,FAM20B,FATE1,ADIPOQ,PLPP6,FKRP,TUSC3,TCEA2,GADD45A,CLEC7A,TMEM147,SFTPC,TMEM182,TMEM39A,KLHL12,TOP3B,CD47,AP1G2,CSNK2B,SERINC1,FZD6,ZNF250,CSGALNACT2,TSPAN15,ITM2B,CLDN8,ENTPD3,TMEM115,VAPB,SMCO4,LEMD3,KLC2,EDDM3B,TMEM231,SYNGR2,CFTR,SEC22A |
| 4.607e-04 | -7.68 | PDHX (pyruvate dehydrogenase complex component X) | protein interactions | 8050 | 100 | 44 | 19454 | 5460 |
LGALS3,STAT5A,TACO1,CCNF,RHOB,PMPCA,MTG2,TUFM,PDHB,NF2,HSCB,RHOU,GFM1,EP300,DLAT,MTRES1,SLC25A3,HECTD1,RARS1,AGTRAP,ATG16L1,CDKN1A,CFTR,DYNC1I2,RHOH,MIF,RAC2,GATD3,CORO1C,USP15,MRPS26,CIDEB,MTRF1,KARS1,HDAC6,PREPL,HSD17B10,DHX9,EWSR1,HINT2,PDHA1,RND3,MRPL11,LGR4 |
| 4.616e-04 | -7.68 | TCF7L2 (transcription factor 7 like 2) | protein interactions | 6934 | 251 | 95 | 19454 | 5460 |
TIMM13,RFXANK,KLF3,CTBP1,KCTD12,XRCC5,FAM168B,ACTMAP,HIRA,EP300,PSMA3,MRPS7,PRMT6,HNF1B,BTF3,ELK3,PARP2,CRYBB3,RBBP4,MAD2L2,MSX2,SOX2,CTNNA2,MTA2,MRPS11,SRSF7,EWSR1,PAX6,RFC2,ANP32B,MRPS35,UBXN6,CTNNB1,HSPB8,ATG7,DICER1,MRTO4,SNRPA1,LYAR,HNRNPL,SMUG1,TRIM35,NUP35,TRMT61A,RPA2,JUP,MRPS34,WRAP53,PML,RPA3,DLAT,FBXW7,HMGB1,WDR3,NPM3,CTNNBIP1,AR,MRPS16,CDC73,CTNNA1,CIB2,ZBTB33,UBN1,LIG3,UFSP1,STUB1,PELP1,UBE2I,CSNK2B,TRIM27,MRPS21,TRAF1,DEK,TIMM8A,IKZF5,EGR2,CBX3,HBP1,TFPT,HSD17B10,CRYBA4,MRPS33,PRDX4,MDC1,RIGI,PTGES3,MRPS18C,PSEN1,CSNK2A1,EEF1AKMT3,TIMM8B,MRPS9,SSBP1,SPPL3,TMPO |
| 4.638e-04 | -7.68 | Histone_H2A | interpro domains | IPR002119 | 19 | 13 | 18521 | 5414 |
MACROH2A1,H2AC7,MACROH2A2,H2AB1,H2AX,H2AC4,H2AZ1,H2AC6,H2AC25,H2AJ,H2AC14,H2AC1,H2AZ2 |
| 4.658e-04 | -7.67 | SYK (spleen associated tyrosine kinase) | protein interactions | 6850 | 248 | 94 | 19454 | 5460 |
RPS10,LYAR,TRIM15,HP1BP3,NCK1,TRAF6,MRPS26,DDX1,CBL,FCGR1A,PIK3R1,BABAM1,KIT,GTF3C3,RFC2,ABCF1,PPAN,PIK3CG,JAK1,HGS,SART3,CRKL,TRMT1L,TUBA1A,PPP2R1A,STAT1,TUBB,CD79B,FTSJ3,FCER1G,SP1,BTF3,RPL39,NOP53,HADHA,EP300,VAV2,NUFIP2,SYK,ALCAM,GRM1,LCP2,MRPS23,SURF6,HCLS1,CD4,TUBG1,SHC1,FGR,OSBPL8,GRSF1,MOV10,FCGR2A,HDAC6,TICAM1,TLR4,PIK3AP1,MYD88,CLEC7A,TCOF1,MRPS18B,HSD17B10,TLR3,RBM34,GRAP2,TBK1,TP53,EXOSC8,STAT5A,UBB,SRC,DUSP3,PELP1,GAB1,CTTN,PRKRA,UBASH3B,MSN,TLR9,TYROBP,EXOSC1,IL2RB,TRAF3IP2,AR,RPS15,SIT1,HDAC3,PIK3R2,RHOU,MTDH,PRKCA,MET,ATG16L1,GTF3C4 |
| 4.670e-04 | -7.67 | GCN1 (GCN1 activator of EIF2AK4) | protein interactions | 10985 | 319 | 117 | 19454 | 5460 |
NDUFA5,PIH1D1,CSNK1A1,PPT1,UBAC2,NPY2R,DUSP22,NEK7,PGRMC1,EMC1,TRA2B,SRSF2,NPTN,STAU1,SF3B1,HSPA8,HDAC5,EP300,CD40,SNRPA,ILK,BRCA1,MLF2,CASP4,MYC,SCN3B,CUL3,OPRM1,SF3B4,SNRPD2,SNRPD1,LMBR1L,SCN2B,PLD3,MOB3C,EZH2,AQP3,HDAC11,FAF2,SOX2,ISG15,LGR4,RAF1,TOP3B,B3GNT2,UBE2A,EIF2D,G3BP1,CDK20,TESK2,POU5F1,HSPB1,AGR2,DDRGK1,MAPK4,PRPF19,EGLN3,HNRNPL,SUMO2,RPL7,SNRPD3,PHB1,SRSF1,HECTD1,RPA2,STOM,METTL14,GABRA1,CFTR,ATG16L1,CCND1,KDM1A,FBXW7,VIPR1,RNF113A,RPA3,BAP1,HELLS,SIRT7,PML,UBE2H,AR,RALB,VIRMA,KCTD9,NDN,ARMC6,GTF2A1,EIF2S2,PTPMT1,RPS20,ALB,ACAT1,CCNF,CHRM4,ILF2,COMTD1,RPS13,RIGI,HAPSTR1,IGF1R,TNFRSF14,TUBG1,SLC2A1,SNRNP70,RNF14,ERCC3,PTP4A3,TMPO,CWC15,CDC5L,LDLR,TES,CD274,COQ8A,ARL10,EEF1AKMT3 |
| 4.672e-04 | -7.67 | pleura | COSMIC cancer mutations | pleura | 4914 | 1501 | 16828 | 4835 |
FMOD,NEURL2,TBC1D16,CMTM7,SNX12,IRF4,CCND3,RAB11B,ARL6,FGF3,USP13,PLP2,NUP62,SMG5,RNF139,NDP,SH3BGRL,SRSF4,TNPO2,IL7,RAB9A,APPBP2,USP30,RAD23B,JUNB,FOXJ3,SMAD9,PTPN5,BCAS4,TCEA1,CHN2,VCPIP1,RPS3,DDIT3,CTNND1,KPNA2,STK38L,DDIT4,SMYD3,RAB3A,PIGC,SHC3,CDC26,SUV39H1,RGL1,TFRC,CKS1B,AUH,RBM41,FOXI3,PABPC5,HMGA1,PRKCB,SKP1,PCYT1B,GJB1,LCP1,PLCL1,DIRAS3,YWHAH,ADAMTS20,DUSP22,HDAC11,DNAJC7,BCL2A1,ATP6V1D,CDKN2D,CDK17,EEF1B2,PTPRZ1,ZNF189,SUPT4H1,MYLIP,VPS39,TFDP2,TULP3,BMPR1B,ETFB,RANBP10,MPP1,FOXC2,PITPNA,RAB32,WNT10B,SPSB1,APOBEC3B,RBBP9,FBXO11,MLH3,PCBP4,COX7B,RHOG,FAM83A,ASB11,SDHC,RGS1,KPNA6,IRF8,TOX,GAD2,ASCC1,KIN,SMUG1,DUSP18,TP53,PPM1B,TRIM35,FBLN5,FOXD3,GPC4,CXCL10,SENP8,DNASE1L1,PML,RDH12,SERTAD1,ARF4,HMGB1,GNG11,ARF1,PDCD5,DUSP6,SPHK2,RCHY1,FGR,ARF6,LBR,FBXL7,MAP2K3,DOK5,STYK1,RPL7A,CXXC1,RPRD1B,SMARCE1,RGS6,CETN2,ZC4H2,CBFB,PRDX4,SLC25A14,MECP2,NUP35,TFPT,ALOX5AP,RIT2,TNIK,OR4B1,ORAI2,CHST7,SERPIND1,UBE3A,ENO1,MAGEB1,RNF128,DICER1,PTGES,SAP30,SLITRK5,TLR7,FGF16,MSN,POU5F1,PPP2R5A,MID1IP1,ADK,G6PD,FTHL17,RALA,SERPINB6,SYBU,ZBTB16,MXD1,MFAP1,FBXO34,HCST,BRMS1L,UBE2I,MAP3K3,SAR1B,CCR5,RNF7,CAPG,EZH1,TLR1,RHOU,WDR82,DLG3,RPL22,APOC4,RNF11,CYTH2,RANBP1,ATF3,GNB1L,DNAJC2,ACSS2,MATR3,FZD6,MET,SNX11,UBE2V1,S1PR4,SERPINB9,HELT,CRADD,PPP1R3C,FKBP2,RALB,GMNN,SNRPA1,ABHD2,TP53I3,KDM1A,DDX1,CCDC22,RNF40,ELF1,SFRP1,LDB1,RANBP6,CYP2R1,FGF23,BIRC5,UBE2H,ARL5B,CAMKV,ENO2,PSENEN,PNMA5,CD40LG,PTGER2,MYC,IRF9,HERC3,EEF1E1,VPS26A,RASSF4,SERPINA3,CLK1,TRAF1,PPP1R8,BRS3,ZMAT3,RAB35,MAB21L1,TOP2B,BAD,GPR173,PRPS1,GEMIN8,MYL6,PDCD10,VAPB,PSMA6,PARM1,AKAP1,CDKN1B,COX7B2,NLGN1,HMGN4,AHSA1,PLEKHF1,DUSP10,CDC42,SYK,ACO2,VPS16,TRIM62,PSEN2,SNX1,FTH1,ST8SIA4,NCK1,IL2RG,STRADB,SIAH1,RAB1A,GLO1,PRKCA,PDCD1LG2,AMELX,EEF1A1,PIGK,GAS2,FBXO31,RPL39,TTC33,TESK1,DVL2,BRD3,ALDH1A3,HNRNPH2,ANKRD10,CLIC4,SMARCB1,FOXP1,SLC4A10,TRIM6,PYGB,ENC1,PLCXD3,MMP20,APEX1,AKT2,GAB1,FKBP1A,COTL1,RFC4,RNF5,GRB10,CSNK1E,CHMP2B,PAK6,DNAJC4,POLD4,BCKDK,AKT3,ARHGAP19,CUL3,ARMCX3,NAP1L3,RBBP4,GPR34,XBP1,RPF2,COX6A2,MAD2L2,ERCC3,ATF1,FAS,TIMM8A,KLHL9,EGR1,CHTOP,SNX14,AIFM1,RAP1B,RAD21,AKAP17A,C2CD2L,DNAJB4,ACVR1B,PIK3CG,COX4I1,LRRC4B,UBE2S,RHOH,ANAPC4,ARHGAP15,CORO1C,RACGAP1,GLRA2,HDAC3,RBM3,MAGEA4,ADAMTS10,UBE2G2,EP300,MECR,UPRT,AKAP8L,FXN,RNF8,PEA15,CYTH4,CPNE2,APOBEC3F,PLCB2,MAP2K1,FEZ1,EIF4A2,MAGEH1,OTX2,TRIM26,STAT5A,COPS5,SNRPB,TPM3,RIT1,PTPN4,FAM3C,PTP4A2,VEZT,LYZ,TOPORS,WSB1,LAMP2,NLRP9,SLC25A5,AR,ADCK1,DMPK,CDC23,USP3,MPG,TGFBR2,CDNF,TANK,TNFRSF1B,VAMP7,KCTD3,CTTN,RPL23,SPIN3,RABGGTB,NKAP,FBXO7,GNGT2,OR5M9,RRAGB,PPP2CB,GABPA,FKBP8,RASL12,SMAD1,TIMP3,GMPS,PPP3R2,PRSS12,TTL,CCR7,FCGR2B,DUSP3,SUCLG2,BIRC2,MTM1,SIAH2,CER1,RUNX1,GJC1,SS18,TYMS,UMPS,SCML1,DIRAS2,ARHGAP12,UBP1,IGF1R,CX3CR1,MAGEC2,MCM4,PSEN1,EDA2R,FAM177A1,LMO2,FKBP1B,STARD4,THOC2,ORC6,CLEC6A,DROSHA,MGMT,SP1,MDC1,IMPA2,FEN1,FUNDC1,PRKACB,ASB7,TRAM1,TADA3,ERAS,PLEKHO1,MYBL2,CNOT2,SPRY1,ROCK2,KRIT1,TRAF6,ELF5,SCML2,DNAJC19,TKTL1,ETF1,LRRC8B,NCAPG2,POLE3,PREB,NFKBIA,RNF10,RNF34,RAP2A,MSH6,PPP1R11,COPS7B,DENND2D,KLF4,FBXW4,SERPINC1,HLF,P2RY4,IP6K1,GPM6B,FBXO22,RFC3,RPL10,PTPN11,NOTCH2,FBXL4,UNC79,FAF1,SRPK2,TAB2,TP53INP1,TRAF3IP3,DTWD1,ASTN1,RPA2,CCR1,CD40,TNFSF15,SLC6A2,TLR8,ARFGEF1,TNFSF8,PDE2A,CLCN6,ZNF428,CTTNBP2,RGN,RAB6A,FKBPL,USP16,TCEAL1,PLAC1,CDK7,SIN3A,BTG3,SYNCRIP,GADD45A,GRPR,PPP1R1A,MSTN,RNF148,PIGA,SAP18,DDR1,TOR1B,SPSB3,HSPD1,EIF1AX,CCNH,POLA2,POLB,PIAS1,PNPLA4,WDR45,SNRK,HSPB6,GNA11,SRSF2,SERPINB1,HSPA5,STUB1,PIP4K2C,GPRASP2,PQBP1,ACVR1C,NKIRAS2,PLS3,TRIM44,TNKS,SLC22A17,STK4,PPP2R2C,ITGB8,BTG2,VAV2,CCDC3,GNB3,HINFP,CSNK1G3,RAB39B,PGRMC1,FTSJ1,PTK7,DHX38,HUWE1,COX8A,CPLX2,USP8,UBE2L3,PMAIP1,BCL7C,B4GALT4,TCEAL8,TRIM34,ITGB5,RGL2,PPFIA2,FBXW11,NINJ1,HR,ZBED1,DKC1,FBXO44,PNMA3,RB1,TRIM29,GSTA2,MCL1,PLD3,NDUFA1,HFE,SPRED2,PCNA,DDX23,PIK3R2,NDUFS6,JAK2,TRIM36,NT5DC1,TNKS2,HSPB2,NXT2,STK3,DCAF12L2,IKZF5,RHOBTB1,PTP4A3,FZD3,RNF144B,DNAJB9,PLCB1,GNAZ,OR10A4,USP15,APOBEC3G,TSR2,NTRK2,SPP1,GNG12,CDK12,FBXW7,EPHA4,PSMD10,TNNI3K,ARL4D,CITED1,CCDC160,STAMBP,EPHX1,CXCL13,CKS2,RORB,MAGEB10,CXCR3,PCGF6,SDHB,RLIM,PTEN,SURF2,MAGED2,CCNA2,UAP1,YWHAZ,ICAM2,BOK,TNR,RND2,PPP1R1B,BMPR2,BCL9,RASD1,CBX3,NLRP3,ILDR1,IER2,HSD17B10,DKK1,HERC4,USP6NL,SNX10,ZMYM3,OXSR1,DLST,ORC5,BAG3,BCL6,KRAS,RBM22,RRM1,CDH11,PIK3CA,TMEM185A,SF3B1,APEX2,SUFU,FBXL19,TMEM47,AP1S2,CHIC2,NUF2,COX6C,PICALM,DAPK3,COCH,RAPGEF5,BAX,CRTC2,CD81,ELK3,DPH3,RHOBTB3,DDX46,OCRL,UBE2E2,GANAB,RPS6KA4,FBXL14,RHEB,PRKCE,TSPAN17,RAB27A,GRAP2,TRIM15,RNF133,COX6B2,DAAM1,NF2,PARP2,HSPA13,SESTD1,FOXA3,SH2D1A,PPP2R5E,NUDT9,TNF,CCR4,KLF3,SERPINA1,SUMO2,CDC7,ST6GAL1,FBXO8,SGMS1,RBBP8,CBLL1,UBA3,SRSF7,TRIM45,SAV1,STAT2,DUSP21,CYP2C9,SNX22,CDC20,NCDN,GNAO1,TIMP4,XRCC5,IRAK4,FHOD3,WDR11,NHEJ1,TBC1D25,NBN,IL2,FGF12,EZH2,FKBP10,INPP4A,RAB9B,RPS27L,DYRK1B,TESK2,STK11,WIF1,TP53INP2,SNX24,STAT6,LAMTOR3,ARL4A,LITAF,CCNF,WDR44,CTNNA1,RAB2A,MEF2C,FUT1,BAP1,RPRM,RAB37,SCYL2,PHKA1,FBXO25,DNAJC10,RAF1,STK38,PRRG1,WEE2,RAB5C,PNP,RNF14,PCDH19,DET1,MCHR2,EIF4A3,DDX5,ADNP,PPP2R1A,RAP2C,SMAD3,TIMP1,UBE2F,FOXP2,CCHCR1,IL6ST,CYTH1,SNIP1,UBE2D1,RGS5,RPAP2,INHA,RAB1B,RBMX2,TNFRSF14,LDHAL6B,CDKN1A,RP2,FOXN2,SLITRK2,FBP1,CLIC2,NLRP1,PPFIA3,CRKL,SOS2,KDSR,DNAJC27,E2F4,PPM1G,MAX,TCEAL7,RHOB,PCGF3,TRIM11,PROM1,TOPBP1,G2E3,MRGPRX2,GNAI2,DDX4,CAB39,KLK5,CBX5,TOP3B,ADAMTS1,CXCL14,RRAS2,CLDN8,BNIP3L,RERG,NUP153,OTUD6A,COPS7A,RNF20,DDX42,PPP1R16A,PGR,HSPA14,CXCR4,PAFAH1B2,ANAPC13,HDAC6,RNF39,ASB3,RNF122,SERPINA5,BTG1,ZMYM4,BICD2,GNA14,CXCR6,RAN,TSC22D3,USP14,MMADHC,APLN,TMEM164,YWHAB,ZNF609,PLEKHA8,NUS1,ZCCHC12,UPF3B,RABL3,NFYB,PPP1CB,SESN2,TPBG,LILRA1,DAPK1,PDE1A,KLHL15,CDK5,GNG3,RNF26,TNRC6C,RAB13,RNASEL,UTP23,TNFSF18,RNF167,TOB2,RAB33A,CCR3,OGG1,SUMO3,OPHN1,PPFIBP1,PTGER1,RAB23,WWP1,RHOJ,CBLN4,PKIG,JUN,ZNF507,STAT1,PAX6,FANCG,RB1CC1,PPID,P2RY11,RPN1,FOS,SP4,DYRK2,DYNLT3,EGLN3,RPL26,TMCC1,RIOK2,RAB14,APOBEC3D,HNRNPK,RAB5A,PC,PRKAG1,NFKB1,NEK2,F10,MAFG,TMEM31,CCR2,ZC3H7A,DSTYK,GNG5,IPO8,HMG20A,TLE1,GPHN,POLE4,HSP90AB1,FUNDC2,CSRNP1,PADI2,SYP,ATG4A,SFRP4,DNAJC22,TMX3,ARHGAP25,BCL7B,PGPEP1,F9,CXCL12,PPM1D,IDO1,SERPINI1,KLHL12,APOO,SNX17,TOP1,TNFSF13,GIT2,NKIRAS1,RUVBL1,RAB3D,ICAM3,KDM4B,YTHDF1,RGS19,RCE1,TRIM54,RASGRP3,CDC42EP3,MCM3,RAB33B,CREBBP,PDCD4,LDOC1,METTL2A,NLRP6,AKAP14,CHRDL1,FAM162A,CCNB1,PIP5K1A,ADIPOQ,ERH,UHMK1,PTGER4,TRAF3IP2,GNG2,TERT,MAP3K11,PIK3R3,GTF2H2,MORC4,SRC,IDH1,GNG13,SAT1,RASL10A,PTPN22,SOCS3,FOLR2,NFKBIB,RAC2,MMP21,STK24,LRP6,RNF121,PGAM1,DDAH2,PAX9,ACTB,CNTN1,GNB4,PRKAB1,DERL1,RFC2,SNX18,LNX2,SOX2,CSNK1A1L,TAS1R2,SERINC3,KLK6,DNAJC3,MFN1,STAU1,PLA2G12A,TSN,PFDN4,SST,NPR2,CDK4,RAB30,TRAF2,BRCA1,BCL10,NOS1AP,DNAJB2,PDHA1,DUSP19,PPP4C,NME1,NAA35,RGS2,LGR4,EED,DYNC1I1,CIB2,ACSL4,TRIM24,EWSR1,PPP1R12A,HSCB,TFEB,HSPA8,VMP1,DNTT,GOLGA5,OSBP,BECN1,LMNB1,SSRP1,MED21,RAB22A,AK5,UBE2V2,SMC4,FCHSD2,MOSPD1,EFNB1,RNF113A,PIR,UBE2M,UBE2E3,TFE3,TRIM10,CSNK1A1,ITGA6,DDX39A,AKAP12,IGBP1,RNF126,FOXP4,LDHB,ITGAV,CDKN2C,COX4I2,USP5,MXI1,EIF4E,TRIM5,NUP37,FZR1,SMAD4,PPP2R3A,BAK1,CD274,FAIM,ELK4,SMARCA5,DRAM1,UGT2A3,RAB3B,GRAP,DCP2,BAG2,JAK1,MLF1,ZBTB33,FBXO42,MCM8,SERPINB10,DLAT,FZD4,EXT1,VRK1,JUP,PGK1,DNAJC5,ZMYM2,ZYX,CFL2,SNX5,MMP9,BUB3,PLP1,RNF41,LMNA,PHF1,CYP3A5,KIT,RS1,CSNK2A1,KPNA1,GNG7,CTNNBIP1,TMEM74,OR8K1,ARMCX5,RAB31,DRP2,DYRK1A,RAB18,INSM2,FKBP14,IDH2,AGER,C1GALT1C1,EIF2AK2,TRIM27,COPS2,ANAPC2,FBXO32,AGK,SHC1,FGFR1,NME2,PPP3CA,SRP54,PCK2,CAMK2G,PRMT2,CIB3,ACO1,SATB1,SCFD1,RABL2B,FAM199X,ARHGEF6,FRMD8,USP2,ADRB1,ZDHHC14,PCDHB8,HEY2,ARMCX2,TRIM21,NSA2,CAMK1,SNX2,PTTG1,PTPN1,TRIM37,HECW1,SEC63,RBBP7,NOVA1,RMND5B,L1CAM,AKT1,FGD2,IKBKB,DKK3,TRIM8,RAB11A,HRAS,ASMT,PFDN5,COX10,CDK8,CNP,RND3,TFG,SOCS5,AK2,WDR83,MDM2,EHBP1,MRPL13,FBP2,ZMPSTE24,MAP3K12,ZDHHC15,RSPH1,E2F6,SOX3,RPS4X,KLK9,ALKBH2,NCKIPSD,DOK4,ARHGAP1,RNF141,NFE2,TRIM32,PRIM2,POGK,CD99L2,PGM1,IKZF2,LIG3,PRKCQ,TRIM3,CCR6,LDLR,FOXP3,XAGE5,PPP5C,APOBEC3A,ZNF319,ID4,MAD2L1,MAP2K6,CDK5R1,RASGEF1C,LMO4,CLU,ANAPC11,GNB1,CASK,CDC16,LTBR,ASB8,INPP5E,SOCS4,MED9,UBE2A,ARMCX1,UBE2D3,CXCL11,CCT2,GHR,SLC6A8,TRIM23,IRF1,CUL2,PYCARD,PPP1R2,GNAI3,DHRS4,RAG1,SFN,RING1,ENY2,KLK3,SLC30A5,SMARCD3,MRPL50,ITK,SWAP70,MYL12A,TRIM46,HCLS1,DNAJC1,CTNNBL1,IDH3B,TIAM1,SENP5,TRIM63,JAKMIP1,GPAA1,SNX3,SIKE1,NCOA5,IGF2BP1,RUVBL2,NFE2L2,RAD1,GNAQ,SPRED1,NONO,PITPNB,POLL,SMAD2,USP46,IQSEC1,IREB2,SIRT7,RABIF,ETV6,TNFAIP3,RAP2B,DUOXA2,MTMR12,TRAF7,CDC5L,SMURF1,FKBP4,PSKH1,SOCS2,UBE2N,CTNNB1,RAB8B,CDK6,TAF2,NCSTN,SGMS2,DCAF5,SLC38A2,P2RY10,CERK,USP39,USP38,VAMP1,CBX7,PROX1,CX3CL1,FGF13,PRKX,LSM6,PEBP1,NAB1,IL5,DIRAS1,KLF10,ARHGAP21,MCM6,RHCG,ITM2A,BMPR1A,ADH1A,NR0B1,SPOP,CASP4,COX7A1,FBXO9,SASH3,CCND1,IFT57,ACVR1,ANP32B,BCL2L1,DCAF8L2,DMAP1,MTAP,RAB3C,TNFRSF9,BATF,DUSP1,PAQR8,NFYA,PPP1CC,DUSP9,AKR1A1,RBPJ,CXCL9,DEK,PRKD3,SLC5A6,RNF152,NUP107,EGLN2,CDKN3,BPGM,NKRF,MCPH1,SLC35A2,ID1,CYC1,POU1F1,FBXL3,INPPL1,ASB1,RGS10,KIF2A,APOBEC3C,MED13L,NSDHL,EXOC2,XPO1,IDH3A,THRAP3,RFC5,RNF103,ASRGL1,XPO5,POU3F4,UBL4A,HDAC5,HECTD3,FATE1,DNAL4,YES1,LDHA,VAC14,GAPDH,GSK3A,NEK9,FURIN,CDK5RAP3,TNFSF10,FAM3A,UBE2B,CSE1L,FBXO3,AGAP2,TSSK1B,PHKG1,PICK1,NTRK3,NEK7,RNF146,SAP30L,CIRBP,G3BP2,RAB4A,DHX16,HADHA,DCLRE1C,LHFPL1,SUMO1,HSPB1,POLD2,KDM2A,TSPAN7,SIPA1L1,HSPE1,PIK3R1,SERPINH1,NLE1,EPHA2,MAPRE2,SNAI3,XPOT,CXCL1,APH1A,ITGA2,COX6B1,SRSF1,MMP14,RAB6B,RASGRP2,ST13,FBXO30,WWP2,RABAC1,RAP1A,NEDD8,CXCR1,MRAS,MDH1,ELK1,RAB28,KCND2,KCNK17,COPS4,KLHL23,CDKL2,GAS8,TAC1,LMBR1L,CBL |
| 4.684e-04 | -7.67 | IVNS1ABP (influenza virus NS1A binding protein) | protein interactions | 10625 | 149 | 61 | 19454 | 5460 |
HNRNPF,HNRNPK,THRAP3,RPIA,TOLLIP,MCM6,VTA1,MSH6,PRPS1,HAPSTR1,PRPSAP1,DHX9,ILF2,HNRNPL,CAV1,HSP90AB1,SYNCRIP,CRBN,NCK1,PDCD10,HNRNPD,YWHAB,USP15,IFI16,EMC4,RPL6,HNRNPA1,YWHAH,TRA2B,UFL1,STAU1,HSPA5,G3BP2,POLR1H,BAP1,PEBP1,HSPA8,EXOSC4,UBE2M,PRKCA,CAV2,ATP6V1C1,CDC42,GTF3C4,ELK4,DAPK1,ACTB,SMURF1,SH3BGRL,VIRMA,ENO1,GANAB,YWHAZ,IVNS1ABP,RC3H2,IGF2BP1,UBE2H,CSK,HNRNPC,HNRNPAB,MCM4 |
| 4.710e-04 | -7.66 | IBTK (inhibitor of Bruton tyrosine kinase) | protein interactions | 25998 | 120 | 51 | 19454 | 5460 |
ZC3H7A,PTGES3,RFC3,COPS4,G3BP1,KRAS,ISG15,RAF1,TOP3B,SRP72,EZH2,COPS2,RPLP1,ITK,EGLN3,CAND1,CD81,RPL6,MOV10,POU5F1,PRKCB,RFC4,RPA3,RGS2,STAU1,FTSJ1,FXR2,B9D2,GKAP1,PRKCA,RPLP0,LARP4B,RPA2,RPS9,RPS20,GSK3A,POP7,RPS3,ESR2,RPL10,RPGRIP1L,LAMTOR3,PRKCE,RPP25L,EIF4A2,CUL3,CSK,AKT1,PDCD4,BICD2,DCAF4 |
| 4.710e-04 | -7.66 | TFDP1 (transcription factor Dp-1) | protein interactions | 7027 | 120 | 51 | 19454 | 5460 |
SOCS3,ERLIN2,MAX,COMMD8,CCT5,TP53,E2F4,ZRANB2,CBX3,RING1,SLC25A10,CCT8,PCGF6,PAX6,FOXP4,KRAS,ATG7,COMMD5,FOXP1,BRD3,CDK6,RB1,CAND1,RPL35A,COMMD6,PRNP,KLF12,CDKN1A,CCNA2,NTPCR,E2F6,MXD1,CDK1,KLF3,HSPA8,YAF2,ATP5MK,SERTAD2,FOXP2,PRPF31,GMNN,MYC,CREBBP,TFDP2,ZMYM2,TRIM24,TNFRSF1B,CDC20,SIAH1,SNRNP40,RBBP4 |
| 4.711e-04 | -7.66 | Gene Expression | REACTOME pathways | R-HSA-74160 | 1821 | 632 | 10285 | 3229 |
CBX3,PSMD1,TFIP11,RPL28,AKT1,SNRNP70,HSP90AA1,PRELID1,PRMT5,POLR2C,URM1,SMAD4,SNRPB2,RGCC,SPCS3,CITED1,MAP2K6,EZH2,ASZ1,CNOT6L,DEK,RPL13A,RTCB,ISG20L2,SAP30BP,IMP4,PSMA1,GEMIN8,EMG1,SEC11A,NBN,SNRPD3,DDX39B,CHTOP,NOC4L,MAGOH,DHX16,H2BC14,E2F4,RPL10,TRMT11,JUNB,RPS3,RPL22,UTP15,EIF2S2,ADAT1,CASC3,DYRK2,GADD45A,CD2BP2,ZNF655,PRDX1,ZNF175,DNAJC8,RPL7,POLR1B,ZCRB1,MDC1,IPO8,TNRC6C,TCEA1,SF3B1,GTF2F2,BAX,COX20,ZNF267,RPS7,THOC6,CDC5L,GTF2F1,ZNF189,QTRT2,DROSHA,DHX9,EIF3K,ZNF692,EED,H2AX,SNRNP27,WDR77,XPO5,RPL3,SRSF10,HNRNPK,NUP37,PNO1,RAN,H2BC9,RRAGB,THUMPD1,RFC4,GTF3C3,CTNNBL1,EEF1E1,H2AC14,RBM17,RPS4X,SNRNP48,MED31,SP1,NUP153,PGR,PPARA,RPA3,TSEN54,RBM5,PSMA2,PSMB6,RHEB,RNF34,PRPF19,PABPC1,ZNF200,SNAPC3,PSMA4,SSR3,HNRNPA2B1,MIR636,PSMC4,TRMT112,EIF3J,PSMB1,ZNF436,RBPJ,POLR2D,POLR2L,POLR3H,SNRPG,ZMAT5,NDUFA4,IGF2BP1,PSMD14,COX6B1,POLR2F,DDX42,MRM2,UTP6,MIR939,APOBEC3A,SF3B4,CDK8,HSPB1,KIT,GTF2H4,MED4,PIP4K2C,RPP21,RPS16,ZNF688,ERCC3,SEC61A1,SUGP1,POLR3GL,RPS20,SF3A1,TOPBP1,H2AB1,RPL6,APEH,RPS27A,COX7B,RBBP8,RPS13,LSM5,TP53,RPS29,ESR2,H2AC6,TXNL4A,UBE2D3,THOC3,UBE2I,POLDIP3,COX6C,BRCA1,EIF1AX,EAF2,NCBP2,VEGFA,MEAF6,POLR3B,MAGOHB,CWC15,EIF4E,MAEL,PSMB3,EIF3G,NOB1,HNRNPD,RMI2,PELP1,PSMA5,YWHAB,DHX15,SMARCA5,RABGGTB,PPWD1,SIN3A,TAF7,TAF10,SMN1,RPL27,SNRPB,SMAD3,POLR2G,SUPT4H1,SRP14,MED10,YWHAZ,TAF2,RPAP2,BAZ1B,PIP4P1,RPL29,RPL10A,POLR2I,SNRPA,MYBL2,NUP107,RPL24,TRMT13,NR2E1,EEF1A1,ZNF740,NR1I3,NR1I2,DDX46,CGB8,MYC,RPL32,FAU,EIF4A2,ZKSCAN1,LSM8,SRSF7,SRSF2,TSEN34,EIF4A3,G6PD,POP7,SUV39H1,MED23,COX11,EIF4H,H2BC1,HNRNPA1,DDX4,EEF1G,ING5,SNAPC2,INTS10,PSME2,CARS1,GTF2E1,MAPKAPK5,WDR12,TACO1,RPL19,RPA2,PRDX2,THOC1,INTS12,HSPD1,EIF2B3,RPP14,PMAIP1,H2BC17,GTF2A1,JUN,PAIP1,PPARG,NOP58,RMI1,KRBOX4,CDKN1B,APOBEC3C,LSM2,FTSJ1,SPCS1,ZNF770,TRMT5,CDC40,SAP30,GCFC2,H3C1,COX16,HSPA8,PRKCA,GTF2H2,SRPRB,ZNF790,PRPF4,RRN3,ELOC,SMG8,RPS10,RRP7A,RPS27L,AGO1,IGFBP3,RARS1,PHAX,NUP42,PSMB2,ZNF473,SMNDC1,RPL23A,SUMO1,IMP3,PPP2CB,BCL6,NR4A2,TGIF2,MTA3,ZNF668,GTF2B,RPS24,CREBBP,BUD23,PRKAG1,PSMC1,CDK9,RCL1,DDX39A,LAMTOR3,GTF2H5,HSD17B10,PSMD4,LSM6,EIF2S1,TAF9,TNFSF13,RPLP1,NUP62,DKC1,RPS28,H2AC4,NR0B1,MTA2,RTRAF,RPL15,NABP1,SEC61G,TRMT6,RPN1,RPS5,RAD1,MARS1,THOC2,GTF3C4,SNRPN,SETD9,COX5A,ZC3H11A,TXNRD1,EXOSC8,SRSF4,PTEN,LSM3,TP53I3,HNRNPF,ACTB,BIRC5,FARSA,HNRNPC,FCF1,PCBP4,PHF1,YWHAH,RPL37A,TRA2B,FYTTD1,COX14,PQBP1,RPL39,MNAT1,HNRNPA0,MOV10,EEF1B2,RXRG,POLR2B,PML,SNAPC5,RPL26,CSNK1E,PSMD10,TMEM219,RRAGA,LSM10,CDC73,SAP18,SSR2,RPL7A,XPO1,YWHAG,H2AJ,AKT2,SKIC8,SRPRA,ZNF263,EIF4B,GEMIN7,USP2,BNIP3L,POLR3F,CDK5R1,PSMD12,ZNF343,ALYREF,RPSA,PIWIL2,RPL27A,PRKRA,CCAR1,SRP54,NRBF2,TP53INP1,CSNK2A1,ZNF671,CNOT8,PSMB9,NXT1,SUPT5H,APOBEC3H,ZSCAN25,RPRD1B,SEC61B,OSGEP,RPL26L1,MED17,H2BC11,PSMB11,BUD31,DDIT4,MIR1304,RPL31,RPL12,EXOSC4,CSNK2B,NOTCH2,GPX2,NUP50,RPS9,TSR3,UBB,KARS1,PPP2R1A,BTG2,RPS11,RPS2,TAF1D,POLR1D,H2BC12,RIOK2,UPF3B,GTF2E2,CDK1,RPS15,CDK7,PSME1,SSR1,SPCS2,AKT3,PSMA6,METTL14,LAMTOR2,COX8A,SRP72,CLP1,CPSF2,RPL35A,SNAPC1,DHX38,EEF2,TAF11,SSRP1,TYW3,ZNF664,CNOT2,ELAVL2,NR2F6,SNRPD2,AR,RPL10L,FAS,PSMC3,SMG9,SNRPE,RPRD1A,SEM1,C1D,PLAGL1,DDX1,PRKAB1,PAPOLA,USP39,NHP2,HNRNPH2,KRR1,EDC3,PSMB4,ETF1,DDX5,COX4I1,PRPF31,CDK12,TYW5,SESN3,RPL35,RPL17,SESN2,VDR,CCNH,CRADD,CNOT7,EIF3E,WDR3,MDM2,RPL18,PPIH,RPL9,RFC2,TSNAX,EIF2B5,RBBP7,UBA52,ZNF596,RPS23,GTF2A2,RPS12,TFB1M,RPL4,PRCC,EP300,WTAP,RPP25,ZNF304,NR1H2,ZFP1,RPS14,RBBP4,CTU1,ZNF287,APOBEC3B,TRMT61A,DCP2,EIF5B,H2AZ1,ING2,LAMTOR1,CCNB1,SMG5,PIWIL4,H2AC7,SAP30L,CDKN1A,H2AZ2,NUP35,KCTD15,SNRNP40,TRAM1,MBD3,TFDP2,CCNA2,SF3B6,PCNA,CPSF1,RPLP0,ZNF704,RPS17,CSTF3,SLU7,EIF2B2,EXOSC3,RFC3,RPS26,PIWIL1,RPL8,UBE2D1,RBM22,DGCR8,RFC5,THG1L,UTP25,PSMD6,RPLP2,SEC61A2,CDK5,CPSF4,ANP32A,MIR1234,CSTF2T,CNOT6,SMAD2,SNRPA1,SNRPD1,TXN,PSMC5,SFN,PSMB10,PSMA3,MED30,PSMB5,FOS,DICER1,EIF3D,ZNF250,SF3B5,MIR7-1,HENMT1,LSM4,PSMD3,PSMB7,PWP2,HNRNPL,SRSF1,WBP11,MPHOSPH10,POLR1H,STK11,POP5,MPHOSPH6,PSMD7,EXOSC1,SMARCD3,RORB,TSN,MED27,XPOT,RPL23,DDX23 |
| 4.717e-04 | -7.66 | BDP1 (B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB) | protein interactions | 55814 | 59 | 29 | 19454 | 5460 |
ASF1A,PSMD12,SLC25A5,HIRA,ERP29,EMG1,ZNF574,MFAP1,POLR1D,POLR3F,HNRNPL,FBXO22,SNRPD3,VIRMA,DYRK1A,UBN1,POLR3B,RB1,POLR2F,POLR3H,RPLP2,YWHAZ,RPL24,BAX,RGMA,CALR,RBM17,PSMD1,CSNK2A1 |
| 4.717e-04 | -7.66 | KATNB1 (katanin regulatory subunit B1) | protein interactions | 10300 | 59 | 29 | 19454 | 5460 |
PFDN2,SSX2IP,PFDN4,RPL23,PFDN6,CAMSAP2,CCT2,BICD2,ATP5F1A,PCCB,PFDN5,CCT7,RPS16,TCP1,RPS3,RPL9,PNMA2,RPL27A,PAFAH1B1,CCT5,ARF4,PFDN1,GABARAP,ASB3,RIGI,VDAC1,PHB2,RPA3,KATNAL1 |
| 4.717e-04 | -7.66 | GCSH (glycine cleavage system protein H) | protein interactions | 2653 | 59 | 29 | 19454 | 5460 |
PGM1,NDUFAB1,ING5,LIAS,FEN1,CMPK1,ARCN1,GSTP1,IDH2,PRDX6,HINT2,TXNL1,SOD1,ZBTB16,MED11,PSMA1,ACO2,CIDEB,PAXX,XPOT,GSTO1,GLOD4,NUDT9,MGME1,ENO1,PSMB5,HDHD3,NMI,CLIC4 |
| 4.717e-04 | -7.66 | CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4) | protein interactions | 26504 | 59 | 29 | 19454 | 5460 |
GPR173,RAB35,S1PR4,LMBR1L,CCNF,B4GAT1,ESR2,VIRMA,HNRNPL,ARMC6,AGK,MBLAC2,DPP4,ICAM2,CUL3,TYROBP,RHOB,LPAR2,RNF113A,TSPAN15,KRAS,HSCB,TMEM106A,KLRD1,DIO3,ARL15,STK16,PTP4A2,SFTPC |
| 4.736e-04 | -7.66 | ubiquitin-like protein transferase activity | molecular function | GO:0019787 | 476 | 176 | 18094 | 5411 |
RNF103,ATG3,RNF113A,RNF128,FBXO7,RNF144B,MARCHF3,UBE3A,TOPORS,FBXO3,UBE2K,UBE2I,ASB1,PPP1R11,PRPF19,RNF7,RNF133,PML,TNFAIP1,TRIM15,HUWE1,UBE2B,RNF8,CUL3,TRIM62,TRIM11,UBE2S,UBE2G2,MSL2,RNF40,COP1,RNF148,SYVN1,UBE2M,G2E3,MED30,TRIM10,DTL,RBCK1,ANAPC4,UBE2E3,UBE2N,UBR7,UBL4A,EGR2,WWP1,MED10,SIAH2,RNF34,BRAP,HERC4,RNF122,TRAF3IP2,RMND5B,SMURF1,CDK8,TRIM68,TRIM54,RNF146,UBE2L3,NEURL2,RCHY1,TRIM22,TNFAIP3,TRIM21,FBXO9,AREL1,BRCA1,RNF11,RNF10,TRIM35,CBLL1,RLIM,MARCHF4,RNF41,FBXO44,TRAF2,UBE2W,MAEA,NT5C2,RNF187,MYLIP,RNF167,RNF208,BIRC2,CCAR1,RING1,UBE2H,TRIM63,TRIM23,HECTD3,MED27,MED21,ZBED1,NOSIP,LNX2,UBE2D3,RNF141,RNF20,MUL1,MARCHF9,BFAR,RNF152,TRAF6,TRIM6,CDC23,ZNRF1,GID4,MED31,TRIM8,CDC42,TRIM34,RNF39,TRIM37,HECTD1,UBE2D1,TRIM44,FBXO30,TRIM32,TRIM45,ANKIB1,STUB1,RNF14,HERC3,TRIM27,ATG16L1,HECW1,SHPRH,FBXO11,FBXO22,RNF182,IRF2BP1,MDM2,UBA3,PELI1,PCGF3,PELI3,IRF2BPL,RNF181,TRIM24,CUL2,TRIM3,RNF139,RNF121,RNF26,UBE2F,UBE2E2,PIAS1,TRAF7,MED17,ZNF451,TRIM52,FBXL14,RNF5,ANAPC11,UFL1,FBXL3,TRIM5,FBXO25,WDSUB1,RC3H2,RNF126,WWP2,WSB1,MED11,SIAH1,MARCHF5,TRIM26,VPS18,TRIM36,CBL,UBE2A,KCTD10,RNF115,KLHL9,RAG1 |
| 4.742e-04 | -7.65 | DHX8 (DEAH-box helicase 8) | protein interactions | 1659 | 285 | 106 | 19454 | 5460 |
FGF13,WDR83,SAP30BP,RPL26L1,TFIP11,LUC7L3,RPA2,RPA3,DDX46,SIRT7,RPL26,SUGP1,SMAD2,CDC73,RBM7,RBMX2,RPS3,ENO1,SRPK2,VIRMA,RPL13A,ESS2,CD2BP2,WBP11,RPL15,DDX42,CBX3,IK,RPL3,RBM41,ZC3H11A,SNIP1,ZNF451,RPL17,CDC40,TSSC4,THRAP3,PPIL4,MOV10,RBM17,TAF9,CDK12,RPL10A,TUBG1,SNRNP70,SMAD3,RPL32,AKAP17A,CWC15,CDC5L,CAND1,TOP1,THOC1,NKAP,H1-5,ZC3H14,MFAP1,NUP50,SLU7,SNRPA,DPH6,NKAPD1,SAP18,COIL,STAU1,BAG3,SNRPB,CUL3,HNRNPC,RIT1,POLR1B,H1-1,FTSJ3,RBM27,SNRPD2,SNRPD1,DLST,ESR2,RPL19,SNRPB2,TNPO3,ERH,SNRNP40,DHX38,ZRANB2,SRSF7,MORC2,RPL31,SRSF4,POLDIP3,AHCYL1,DHX16,KRAS,H1-6,DDRGK1,IFI16,PRPF19,RPL6,ZCCHC10,RSBN1L,DDX23,RPL8,PRCC,RBM5,SRSF1,LRWD1 |
| 4.748e-04 | -7.65 | KLF4 (KLF transcription factor 4) | protein interactions | 9314 | 152 | 62 | 19454 | 5460 |
TOP3B,TP53,RPS11,ILF2,HGS,MRPS18B,BCL9,BAALC,MRPS11,RTCB,RPS24,PABPC1,RPS13,MRPS17,HUWE1,DDX50,MOV10,MRPS35,TLE1,MRPS26,DDX1,RPL10A,RPL24,TRAF6,SSBP1,MRPS9,FBXO32,GYS1,ELK1,MRPS23,RPS10,PRNP,RPL27A,PAX9,CTBP1,MRPS34,PPARG,ZNF326,HDAC5,EP300,SKP1,MRPS7,RPS15,STAU1,RPL26,FBXO7,AR,RPS29,CREBBP,CUL2,SP1,RPS5,IGF2BP1,SETD7,MRPS16,MRPS25,MRPS28,FAU,RPL19,USP5,FBXO22,RPL35 |
| 4.776e-04 | -7.65 | negative regulation of defense response | biological process | GO:0031348 | 293 | 113 | 18204 | 5365 |
CD200,PPARA,TRIM21,MIR590,USP15,FGL2,MICB,KLF4,PSMB4,LILRB1,FOXP3,ADORA1,SRC,LDLR,MIR26B,MIR142,MIR15A,IL13,GPR17,PYDC2,MIR126,IER3,TRIM45,TNFAIP6,USP38,IL12B,FGR,MIR223,MACIR,MIR146A,PTGER4,MIR21,LPCAT3,SFN,PPARG,MIR149,IFI16,YWHAZ,MIR31,IL4,TNFAIP8L2,SOCS5,IL20RB,TNFRSF1B,SAMHD1,MIRLET7G,MIR195,YTHDF2,NMI,CNOT7,FURIN,PPM1B,MAVS,MIR204,MIR181C,SERPINB9,SOCS3,LYAR,SELENOS,PSMA1,DUSP10,FCGR2B,ISG15,OTULIN,TRAFD1,FEM1A,SYK,MIR205,GPX1,YES1,MIR145,MIR920,GSTP1,CCN3,TNFAIP3,IL10,MUL1,SMAD3,ADIPOQ,NT5C2,IGF1,BANF1,KLRD1,RNF26,SOD1,IL2,MIR221,NDFIP1,IL22,STAT2,MIR222,EIF4E2,NLRP3,FAM3A,CLEC12B,MIR20A,GHRL,NPY5R,OAS1,RB1,MIR488,MIR16-1,NFKB1,MIR141,ARG2,MIR187,MIR105-1,ACP5,NR1H2,TMSB4X,NLRP6,CD200R1,IL2RA |
| 4.779e-04 | -7.65 | WDR81 (WD repeat domain 81) | protein interactions | 124997 | 36 | 20 | 19454 | 5460 |
SQSTM1,CCNF,EEF1AKMT3,ENO1,RIGI,VIRMA,TMEM237,XPO1,CDC42,HSPB8,LAMP2,UBXN6,IFI35,MOV10,CUL3,NAPA,PPP4C,CCT2,AGR2,BECN1 |
| 4.807e-04 | -7.64 | ADD1 (adducin 1) | protein interactions | 118 | 155 | 63 | 19454 | 5460 |
HAPSTR1,RIGI,ADD2,FLOT1,KRAS,ROCK2,UBIAD1,MAP1LC3B,RAF1,TP53,HEXA,RND3,GEMIN7,CAPZA2,PDHA1,XPO5,RAC2,HRAS,RAB35,CDK9,CAV1,HMG20A,LRWD1,ARF6,RHOH,DYNC1I2,SPTAN1,XPO1,HDAC6,TPM3,IFI16,NDC80,ATP6V1D,RHOG,BAP1,RHOU,RPA3,STX7,ZDHHC17,STAU1,SPTBN1,PRKCA,TMOD1,ARL15,CDK1,LMNA,RPA2,GSK3A,CSNK2B,ROCK1,ESR2,DAPK1,RHOJ,ACTB,DNAJC5,RAB2A,FAM78A,ATP1A1,CDKL2,MAPRE1,CDKN2AIP,FAS,LAMTOR1 |
| 4.807e-04 | -7.64 | ATP2B4 (ATPase plasma membrane Ca2+ transporting 4) | protein interactions | 493 | 155 | 63 | 19454 | 5460 |
TACR3,EMC1,NPTN,GPC1,LPAR1,ADRB2,PMAIP1,DERL1,RAB9A,HSD17B6,FGFR1,CFTR,CDK7,APLNR,VIRMA,SRC,LGALS3,SLC11A2,GPR173,IL2RA,SEC61B,OPTN,S1PR4,LMBR1L,DLG4,TYROBP,ATP1A1,SNTA1,LAMTOR1,RHOB,LGALS8,SLC41A3,DNAJC5,TAS2R7,GPR17,KRAS,EDA2R,HCAR1,DLG1,ATP5PF,VAC14,PLD3,CASK,RAF1,DLG3,OPRL1,CAV1,SPPL3,ARF6,GJA1,LHFPL2,LILRB4,RAB35,HRAS,PLAC9,UPK1A,PPP3CA,STYK1,HM13,P2RY10,CCR6,DPP4,FAM174A |
| 4.814e-04 | -7.64 | intracellular receptor signaling pathway | biological process | GO:0030522 | 188 | 77 | 18204 | 5365 |
TLR8,BECN1,TIFA,PPARG,AR,TBK1,CRKL,NR2E1,IFIH1,TLR9,TADA3,RWDD1,NLRP3,MYD88,TRAF6,FKBP4,PGR,IRAK4,LACC1,ESR2,KCNJ8,EGLN2,CRY1,CGAS,ATAT1,OAS1,TRAF3IP3,MAP2K6,NR4A2,LSM14A,TLR7,IRF7,NLRP6,RIGI,JAK2,TICAM1,PML,IKBKB,ACTN4,MAVS,NR1H2,RBFOX2,NR1I2,WBP2,PHB2,NKX3-1,IRF3,PYCARD,RXRG,CST11,RNF34,PPARA,TLR4,YWHAH,PTGES3,NLRP1,NR1I3,TRIP4,SRC,OTULIN,ERRFI1,TNFAIP3,PIK3AP1,VDR,DDX5,PADI2,PHB1,NR2F6,RORB,NFKBIA,TNF,TAF7,CLPB,TLR3,RNF14,UBE3A,CALR |
| 4.815e-04 | -7.64 | HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor) | protein interactions | 55662 | 313 | 115 | 19454 | 5460 |
PPM1G,RPL27,NCDN,TMEM126B,HDAC3,RPS15,KDM1A,EIF4E,EEF1E1,ACBD6,PSMC4,CHST7,RPA2,TIMM23,CDK1,HECTD1,ZBTB33,STUB1,INPP5K,PSMC5,GMDS,ZNF622,BCCIP,CDC20,SLC25A1,ST13,PIP4K2C,SLC25A11,YIF1A,SRPRB,RNASEL,RIGI,TNKS2,FASTKD5,TP53,MTCH2,TBK1,AZI2,NDUFS3,PSMC3,TNNI3K,AIFM1,EEF1B2,AIP,WDCP,TNKS,XXYLT1,RPS27L,IFRD2,KCTD15,SLC25A12,NFKB1,EDC3,ELOC,ANKRD49,STYK1,SMG9,DNAJC7,NKAPD1,EXD2,AKAP1,ATAD1,SSR3,TMEM177,ASB3,SKP1,TANK,NOTCH2,ASB8,WDR77,FEM1A,RTF2,SLC25A3,NFKBIA,NFKBIB,SEC61B,SIAH1,PSMD4,NDUFAF4,MORC4,POLR2B,MLF2,MCM3,BTF3,OTUD7B,MAP3K21,PSMD14,CCT2,DNAJB6,ILK,NDUFA4,CCT8,MAEA,SLC25A5,RPS24,UBE3A,MYO1B,PCNA,CDK5,CHCHD2,PFDN1,MCM6,FAF2,ZRANB2,POLR2L,CCAR2,AGK,PTDSS1,CLPX,FEM1B,XPO1,PSMD10,ANKRD50,HAX1,ASB7 |
| 4.826e-04 | -7.64 | PYCR3 (pyrroline-5-carboxylate reductase 3) | protein interactions | 65263 | 103 | 45 | 19454 | 5460 |
ARFGAP1,GPX7,KLHL26,DNAJB4,CYTH2,MRPS18C,BABAM1,ZCCHC9,RPL23,PSMB5,PSMB1,FZR1,EGLN3,PSMB3,KLRD1,CDK7,SDCBP,KCTD12,HEXIM1,SNX11,BAP1,FBXW7,HSCB,UFL1,DGCR8,KDM1A,FXR2,CUL3,PYCR1,ZNF687,PYCR2,PRMT6,PSMA4,PSMB2,AKT1,MYC,PPP1CC,NTAQ1,LACRT,UBE2H,PSMA6,GTF2F1,PHF21A,CYTH1,DYRK1A |
| 4.826e-04 | -7.64 | PLEKHA1 (pleckstrin homology domain containing A1) | protein interactions | 59338 | 103 | 45 | 19454 | 5460 |
GJA1,RAB35,CEP19,CAV1,DIRAS3,LRRC61,EPHB6,STX6,RHOH,ARF6,SPPL3,YWHAH,YWHAG,ATG9A,LAMP2,STYK1,YWHAB,RHOG,IGF1R,FLOT1,EPHA4,KRAS,CRKL,RND3,RAB4A,PTEN,SH3BP4,RHOJ,DNAJC5,FBXO7,SFN,RAB11A,CLDN14,NTRK3,RHOB,YWHAZ,LAMTOR1,RAB5A,RAB9A,RHOU,STX7,RND2,CDC42,SCLT1,FGFR1 |
| 4.826e-04 | -7.64 | TXNRD1 (thioredoxin reductase 1) | protein interactions | 7296 | 103 | 45 | 19454 | 5460 |
SLC25A12,HSP90AB1,SPTAN1,FZR1,CBL,AGR2,SMAD4,COPS5,OLA1,PSMD12,RPIA,SEM1,PDIA6,HSPD1,NAE1,PLS3,ISG15,TP53,TXNRD1,ESR2,APEX1,TUBB,GLRX2,CCNF,PAPSS2,PNPO,TXNIP,PPP1R16A,AR,SAMHD1,CUL3,TXNRD2,CDO1,PSMA4,CARS1,CRYZ,HSPA5,FBXL4,PYGB,RP2,TXNDC17,RPA3,EIF4B,UBE2M,RPA2 |
| 4.826e-04 | -7.64 | CENPQ (centromere protein Q) | protein interactions | 55166 | 103 | 45 | 19454 | 5460 |
RPL4,FBXW7,DGCR8,KDM1A,EHHADH,TANK,H1-5,ATG16L1,RPS14,PICALM,AGGF1,MACROH2A2,RPLP0,SCLT1,GIT2,CREB1,TRAF7,RPL19,JUNB,HOMER1,RPL7A,EMILIN1,ATF1,SIKE1,TFPT,STX8,RPL3,RPL28,SRSF4,CENPM,TBK1,H1-3,JUN,RPL18,RPS11,RPL9,STX5,SNX2,RPS16,VTI1B,KXD1,CENPP,CENPL,RPL10A,VPS4A |
| 4.826e-04 | -7.64 | OTC (ornithine transcarbamylase) | protein interactions | 5009 | 103 | 45 | 19454 | 5460 |
MRPS34,NDUFA5,MRPL12,CFTR,NME4,PDHB,NDUFS2,POLDIP2,MRPS7,TOMM20,DLAT,MRPS25,MRPS16,PYCR1,PYCR2,NDUFAF2,ATP5F1B,NDUFAF4,DLST,TACO1,ACAT1,MRPS28,PDHA1,NDUFS3,NDUFS6,NUDT19,NDUFA12,ETFB,NDUFA2,ATP5PB,PPIF,KGD4,ETFA,MRPS17,ATP5PF,PREPL,MRPS18B,MRPS26,MRPS35,STOML2,CLPX,NDUFV2,MRPS23,NDUFS8,MRPS9 |
| 4.826e-04 | -7.64 | RBL1 (RB transcriptional corepressor like 1) | protein interactions | 5933 | 103 | 45 | 19454 | 5460 |
CTBP1,RPA2,CCNA2,TOR1AIP2,CCND1,AATF,PPP2R3A,HDAC3,EP300,AOX1,NLE1,IRF3,RPA3,SP1,EPHA2,SMAD2,BRCA1,TFDP2,RBBP8,AR,MYC,DYRK1A,VIRMA,SNRNP40,RBBP4,CDK4,RBBP9,E2F4,LAMB2,RINT1,PLSCR1,SMAD4,SUV39H1,CSNK2A1,DYRK1B,CDK9,CITED1,SNRPD3,TOP1,CDK6,RB1,EED,MYBL2,PHB1,SMAD3 |
| 4.828e-04 | -7.64 | serine/threonine protein kinase complex | cellular component | GO:1902554 | 136 | 58 | 19108 | 5553 |
CKS2,PYCARD,TBC1D5,CAB39,DAPK1,ATG101,TBK1,GTF2H2,CCNA2,CSNK2A1,CDK12,GTF2H4,PHKG1,RB1CC1,CDKN1A,CCND1,CDK5,CDK4,CDKN2D,PARD6A,RB1,PHKA1,CDK5R1,CCNB1,CDK6,ACVR1B,CCNY,CDK7,CDK8,CCND3,TANK,PRKACB,BCCIP,PCNA,CSNK2B,AZI2,STRADB,CDK9,ACVR1,IKBKB,TGFBR2,ACVR1C,CCNF,CCNQ,STK11,MNAT1,GTF2H5,CNPPD1,ERCC3,CKS1B,CDK1,CCNH,PHKB,XRCC5,AKAP14,SESN2,CCNI,C9orf72 |
| 4.845e-04 | -7.63 | negative regulation of muscle hypertrophy | biological process | GO:0014741 | 37 | 21 | 18204 | 5365 |
MIR214,FOXP1,TNFRSF1B,LMNA,ATP2B4,MIR25,RGS2,PI16,SMAD3,G6PD,MIR1-1,GSK3A,MIR145,TRIM63,PPARG,TOMM70,CAV3,MSTN,SMAD4,PPARA,MIR21 |
| 4.845e-04 | -7.63 | negative regulation of SMAD protein signal transduction | biological process | GO:0060392 | 37 | 21 | 18204 | 5365 |
MIR885,DKK1,FAM89B,MIR204,MIR101-1,MIR26B,LDLRAD4,MIR205,GREM1,MIR146A,MIR23A,MIR140,MIR145,MIRLET7G,MIR130A,NOG,PPARG,EMILIN1,MIR195,EID2,CCN3 |
| 4.848e-04 | -7.63 | SENP6 (SUMO specific peptidase 6) | protein interactions | 26054 | 41 | 22 | 19454 | 5460 |
ZNF330,SUMO2,SNRNP40,CDC5L,MYC,PRPF19,COPS5,TIAM1,SP1,COP1,RPA3,NLE1,PML,RUVBL2,NUP50,FHL3,H3C1,KRAS,RIGI,SUMO1,LMNA,CBX3 |
| 4.848e-04 | -7.63 | KRIT1 (KRIT1 ankyrin repeat containing) | protein interactions | 889 | 41 | 22 | 19454 | 5460 |
LAMP3,RAB2A,RAB11A,UBFD1,FAS,TIAM1,RHOB,RAP1B,RAC2,RAB35,RCHY1,ARF6,DAPK1,RHOJ,RAP1A,TLNRD1,CCM2,PLCB1,SNIP1,PTGES3,KRAS,UBE2K |
| 4.848e-04 | -7.63 | PRKRIP1 (PRKR interacting protein 1) | protein interactions | 79706 | 41 | 22 | 19454 | 5460 |
NUCKS1,SNRPA1,SNRPD3,HNRNPL,APEX1,SNRPB2,SNRPG,EIF2AK2,SRSF7,SNRPD1,SNRPD2,STK24,FEM1A,SNRPE,RIT1,SNRPN,TOP3B,RAF1,CEP70,SNRPB,XPO1,TRAF2 |
| 4.848e-04 | -7.63 | SCLY (selenocysteine lyase) | protein interactions | 51540 | 41 | 22 | 19454 | 5460 |
SNRPD1,EIF1AD,TFG,IDE,FERMT2,CSE1L,ZNF622,REXO2,GGCT,MTPN,TP53,PAFAH1B1,RANBP1,GMPPB,CREB3,LNX2,CNDP2,UBFD1,VPS18,CKB,UAP1,PAK2 |
| 4.848e-04 | -7.63 | TRMT10B (tRNA methyltransferase 10B) | protein interactions | 158234 | 41 | 22 | 19454 | 5460 |
MRPS33,SPPL3,MRPS21,TRIM63,RPS27A,MRPS18C,MRPS23,MRPS7,KBTBD6,MRPS9,MRPS18B,MRPS28,MRPS11,MRPS16,MRPS34,NOA1,MRPS25,MRPS26,RPL26L1,OTX2,MRPS35,INSIG2 |
| 4.848e-04 | -7.63 | LRR1 (leucine rich repeat protein 1) | protein interactions | 122769 | 41 | 22 | 19454 | 5460 |
COPS7A,CUL3,TP53,RAB5C,CUL2,COPS5,ELOC,CDKN1A,UBE2D1,RELL2,PNMA2,ZBTB38,COP1,RIT1,TNFRSF1B,TMEM74,TNFRSF9,COPS2,COPS7B,KRAS,COPS4,FTL |
| 4.849e-04 | -7.63 | SCAF1 (SR-related CTD associated factor 1) | protein interactions | 58506 | 123 | 52 | 19454 | 5460 |
ZBTB2,BUD31,POLR2I,TOP1,THOC1,RPS10,PRR3,SRSF1,POLR2L,RPRD1A,BRD3,SNRNP70,DDX23,RPL17,SSRP1,RPL28,SRSF4,KRAS,H1-6,SRSF7,RPL31,SNIP1,POLR2D,POLR2C,POLR2G,PAIP2B,RPAP2,SUPT5H,TOP3B,RAF1,SRPK2,RPL19,ESR2,RPL10,POLR2B,SNRNP40,CHAC2,ALB,FGFBP1,RPS3,MYC,CDC16,SAP18,STAU1,NKAPD1,RPA3,GSTP1,RPLP0,LARP4B,RPRD1B,RPA2,H1-5 |
| 4.849e-04 | -7.63 | RIOK2 (RIO kinase 2) | protein interactions | 55781 | 123 | 52 | 19454 | 5460 |
RAF1,H2AJ,LBH,ZRANB2,MRPL33,HBP1,RPS11,TAF10,EWSR1,KRAS,G3BP1,MRPS33,FOXN2,RPS13,VPS16,STOML2,VPS26A,XPO1,CSNK2A1,SMAD4,SMAD3,H2AZ1,RPRD1A,HP1BP3,DCK,RPS16,NOB1,NKAP,EGLN3,RPL27A,EHHADH,LMNA,GHITM,RPL26L1,EPHX1,ACACA,HECTD1,SNRPA,NUP50,JADE1,TNFAIP3,MYC,GFUS,ANAPC15,PPP1CC,PIP4K2C,STK11,RIT1,RTRAF,MACROH2A1,TAX1BP1,SPCS1 |
| 4.849e-04 | -7.63 | GNAQ (G protein subunit alpha q) | protein interactions | 2776 | 123 | 52 | 19454 | 5460 |
TAS2R7,ATG3,FYTTD1,CRHR1,NRP1,GNG12,PLCB2,RGS5,CYTH1,CD47,ESR2,GNB1,DUSP22,TSHR,GRM2,PPT1,LUM,TMEM185A,TTC1,VIPR1,GPM6A,CERS2,RGS2,NT5C3A,GNB4,MRGPRX1,PIK3R1,IQSEC1,HDAC6,GNG2,MED21,HAX1,SPRED2,GNB3,HRAS,AIP,ARF6,CHRM3,CKS1B,HTR2A,GNG10,GNG3,NHERF1,PIK3CA,GNAQ,ISG20,CCR1,CCR5,PLCB1,ABCE1,GNG5,CYTH2 |
| 4.849e-04 | -7.63 | HMOX1 (heme oxygenase 1) | protein interactions | 3162 | 123 | 52 | 19454 | 5460 |
UFD1,HSD17B1,GPR17,CREB3,AKT1,TM4SF19,CYB561,ELOVL4,CPSF1,TMEM106A,SSBP2,CHRNB2,STX17,LMNA,SQSTM1,DERL1,HSPA8,SYVN1,TSPAN15,TEX264,TMX2,JAGN1,SLC37A4,SIAH2,PTDSS1,EDEM1,FAM174A,PLPP4,AGPAT1,STX1A,UPK1A,PDZK1IP1,PTGER4,POR,CRB3,MSMO1,TLCD4,RAMP3,FZR1,TNPO2,HPCAL1,SOX2,CCDC47,RNF181,TMEM14B,CCR1,CYBRD1,BSCL2,SRPRB,ELOVL6,RNF115,KRAS |
| 4.860e-04 | -7.63 | TNFRSF10B (TNF receptor superfamily member 10b) | protein interactions | 8795 | 158 | 64 | 19454 | 5460 |
BET1,TMEM231,GINM1,CDC42,RND2,GPR35,FGFR1,RPA2,CXCR4,RHOU,RPA3,ARRDC3,GPM6A,LPAR1,TNFSF10,SKP1,RNF11,CLDND1,CUL3,CYB561D2,VAMP5,TNFAIP3,IFNAR1,DNAJC5,RHOB,FAS,LAMTOR1,MARCHF3,VAMP3,SLC1A1,MSN,NDFIP1,RHOJ,TP53,FASLG,IFNGR1,TRAF2,TMEM59,ACVR1,PTRH2,TFRC,TMEM31,IL20RB,TSPAN3,UGCG,STX12,CD83,DDR1,LTBR,TGFBR2,KRAS,RIGI,MICB,RHOG,SLC20A1,CBL,ZDHHC15,PLPPR1,RAC2,RNF128,RHOH,ASIC1,CAV1,OPRL1 |
| 4.860e-04 | -7.63 | CNOT3 (CCR4-NOT transcription complex subunit 3) | protein interactions | 4849 | 158 | 64 | 19454 | 5460 |
GARRE1,LSM14A,PABPC1,BAG2,ZC3H7A,KRAS,CNOT7,TSSC4,TOB2,CAPZA1,MNAT1,CNOT6L,YTHDF2,TNRC6C,SOX2,CAPZA2,PIK3CA,GPBP1L1,FUBP3,THOC2,PAIP1,CAND1,CNTROB,EGLN3,DPY30,CNOT2,CNOT8,XPO1,CPEB1,DRG1,RPA3,EP300,HSPA8,YTHDF1,FBXW7,FXR2,KDM1A,TANK,ATG16L1,ACTL6A,ELP3,CCNH,RPA2,CTTN,CNOT6,TRIM24,RPS20,TAX1BP1,FANCD2OS,DYRK1A,APEX1,BTG3,PRRC2A,ESR2,CEP85,CREBBP,RUNX1,GADD45B,RC3H2,CIRBP,RIT1,UBE2H,UHMK1,OAT |
| 4.862e-04 | -7.63 | EARS2 (glutamyl-tRNA synthetase 2, mitochondrial) | protein interactions | 124454 | 89 | 40 | 19454 | 5460 |
MRPL11,HCST,LMNA,METTL14,PDHA1,MTRES1,RPA3,SLC25A10,AMACR,EXD2,VIPR1,GFM1,SQSTM1,COX8A,HSCB,TNFSF8,NPTN,KRAS,SLC6A8,IMMP2L,GRSF1,AUH,CUL3,P2RY10,TUFM,SMAD4,TAFAZZIN,SLC2A1,RIT1,HTRA2,SSBP1,CCNF,TACO1,AIFM1,LMBR1L,COX4I1,FAHD1,GATD3,PRNP,EGLN3 |
| 4.862e-04 | -7.63 | PTGES2 (prostaglandin E synthase 2) | protein interactions | 80142 | 89 | 40 | 19454 | 5460 |
UQCRC2,CYB5R3,UQCRQ,ESR2,MAD2L2,VIRMA,SLC25A12,NUP35,RANBP6,ATP5F1B,FZR1,BTF3L4,MYC,PDCD10,NRP1,UQCR11,SMAD4,POR,STK24,GNG5,MLC1,HADHA,SHISA2,METTL18,NDUFA4,SFXN1,EMC1,HSCB,ADRB2,UQCRC1,H2AX,E2F4,TPT1,PTGFR,CYC1,LMNA,HSPA13,RPA2,CHMP1A,PDHA1 |
| 4.862e-04 | -7.63 | PLAA (phospholipase A2 activating protein) | protein interactions | 9373 | 89 | 40 | 19454 | 5460 |
BRCA1,CBL,FIS1,FAM174A,GPR17,UBXN6,MYC,PDIA3,TUFM,AR,HDAC6,FZR1,CAV1,EGLN3,ST6GAL1,PHB1,FBXO32,CD79B,SCN2B,LMBR1L,XXYLT1,TES,EMC9,CA14,RPA2,PAK2,CYB5B,TP53,AKR7A2,B3GALT4,HCST,TGFBR2,SEMA4C,CSE1L,NSFL1C,XPNPEP1,SRPRB,RPA3,HSPA8,PCNA |
| 4.862e-04 | -7.63 | FNDC9 (fibronectin type III domain containing 9) | protein interactions | 408263 | 89 | 40 | 19454 | 5460 |
CYB5B,TMEM182,SFTPC,CTSA,PLP2,UBIAD1,SEC22B,PGAP2,EDDM3B,AGTRAP,PLPP6,TNF,KRAS,NSG1,TMEM60,NINJ1,ADIPOQ,ENTPD3,TMEM254,PGA4,EMP3,CLDN1,JAGN1,STX8,CLEC7A,PLN,TMEM100,DOLK,SLC35A1,CLDN11,CLEC1A,VAMP5,TSPO2,ITM2A,CLRN2,AIG1,CXCL9,TWSG1,PLP1,RPRM |
| 4.875e-04 | -7.63 | cellular response to inorganic substance | biological process | GO:0071241 | 214 | 86 | 18204 | 5365 |
MEF2C,SUMO1,CYP11B1,TUBA1A,OGG1,SLC41A1,KCNH1,ALOX5AP,SLC25A24,EIF2S1,MT1M,GSK3A,MAP1LC3A,GUCY1B1,B2M,NCSTN,HSP90B1,GLRA2,AQP2,CPNE2,MECP2,RASGRP2,NSMCE3,MT1A,MCOLN1,NFE2L2,FOS,CYP1A1,CCNA2,NPTX1,PPIF,FABP4,HSD17B1,CPNE1,MT2A,BECN1,CLDN1,MIR342,MTF1,SLC12A2,TSPO,NQO1,TLR9,CDKN1B,TF,MMP9,MT3,NEK7,HPCA,ADD1,SLC1A1,CRHBP,HNRNPD,CREB1,MEF2A,TRAF2,EIF4A3,KCNJ10,GLRA1,CLIC4,NLGN1,CALR,CYP11B2,DPEP1,UCP2,SLC13A5,KCNB1,ATF4,DDI1,CER1,DLG4,MT1E,PRNP,MT1X,RTF2,BACE1,FBP1,NEUROD2,SLC25A23,HFE,AIFM1,AKT1,HSPA8,JUNB,ATP5F1A,JUN |
| 4.878e-04 | -7.63 | EBNA-3B/EBNA-3C (nuclear antigen EBNA-3B;nuclear antigen EBNA-3C) | protein interactions | 3783763 | 6 | 6 | 19454 | 5460 |
MYC,PSMA3,RB1,MRPS18B,SUMO2,BCL6 |
| 4.878e-04 | -7.63 | RENBP (renin binding protein) | protein interactions | 5973 | 6 | 6 | 19454 | 5460 |
REN,P3H1,ZBED1,HSPE1,SCML1,RAF1 |
| 4.884e-04 | -7.62 | positive regulation of signal transduction by p53 class mediator | biological process | GO:1901798 | 30 | 18 | 18204 | 5365 |
SPRED1,MIR186,EEF1E1,ZNHIT1,PML,MSX1,RPS7,CDK5RAP3,MYC,HEXIM1,PMAIP1,RPS20,RPS15,RPL23,UBB,RPL26,DDX5,SPRED2 |
| 4.887e-04 | -7.62 | VARS1 (valyl-tRNA synthetase 1) | protein interactions | 7407 | 230 | 88 | 19454 | 5460 |
EEF1B2,TFE3,CEBPG,TMPO,CDK9,COPS5,SHC1,H2AC4,TMOD2,USP15,MAP1B,RAB1A,PSME1,HUWE1,MLLT6,EEF1A1,CCNF,TUBA1B,PAFAH1B3,MACROH2A1,CFAP298,MSN,VIRMA,SMARCA5,KPNA6,UBE2H,BAP1,RPA3,DERL1,KDM1A,MARS1,CDC42,RPA2,METTL14,PRKCA,UBE2M,HEXIM1,LEMD3,DUSP6,EED,COPS2,PAIP1,SUMO2,IFI16,INSYN1,NT5C2,FOSL2,TRAF6,PCNA,KRAS,RBBP7,RUVBL1,CBLL1,RAF1,JUN,TUBB4B,EZH2,NME1,MOB3C,CYB5B,SART3,LMBR1L,EFHD2,PHKB,SNRNP40,RBBP4,MYC,CUL3,ATG101,UFD1,BRCA1,HSP90AA1,RIT1,FOS,HSPA8,HADHA,RAB5A,BET1L,EP300,EEF1G,PAFAH1B2,STAU1,LAP3,ADNP,MAP2K1,CNDP2,PIH1D1,CAV2 |
| 4.887e-04 | -7.62 | LARP4B (La ribonucleoprotein 4B) | protein interactions | 23185 | 230 | 88 | 19454 | 5460 |
SECISBP2L,H1-6,G3BP1,ZC3H7A,FHL3,SRSF8,RPS24,RTCB,TRIP4,LSM14A,PABPC1,FAM136A,RPS11,EZH2,PAIP2B,TNPO2,RAF1,TOP3B,SRSF10,FAM98A,PAIP1,SRSF1,FUBP3,PHB1,RB1CC1,DDX1,XPO1,CPEB1,TRA2A,IFI16,ASB3,G3BP2,FXR2,YTHDF1,STAU1,AKAP1,NUFIP2,NCOA5,GKAP1,PABPC5,ESR2,RPL10,PRRC2A,LMBR1L,IRF2,ATXN1L,HSP90AA1,MYC,APOBEC3B,HNRNPC,CUL3,SRSF12,ZC3H11A,HBP1,APOBEC3D,STRBP,YTHDF2,RBM42,DKC1,FZR1,RPS16,SYNCRIP,EEF1AKMT3,SNRNP70,TDRD7,COPS5,APOBEC3F,MOV10,RNF113A,MTDH,RPA3,SIRT7,ZNF326,RBMS2,CCL3,RBFOX2,RPS20,PSPC1,CCNF,SMAP2,PAIP2,ELAVL2,IGF2BP1,PPIG,UBE2H,CASC3,RC3H2,DEPDC1B |
| 4.890e-04 | -7.62 | cytoplasmic side of lysosomal membrane | cellular component | GO:0098574 | 13 | 10 | 19108 | 5553 |
BORCS6,SNAPIN,BORCS5,BLOC1S2,BORCS7,CDIP1,BORCS8,KXD1,LITAF,EEF1A1 |
| 4.891e-04 | -7.62 | symbiont entry into host | biological process | GO:0044409 | 115 | 51 | 18204 | 5365 |
CD209,RPSA,WWP2,SLC7A1,ICAM1,HYAL2,AVPR1B,CLDN9,TFRC,PHB1,SLC20A2,LAMP3,CD86,ITGB5,ITGAV,CDK1,SRC,EPHA2,CLDN6,DAG1,HTR2A,LDLR,VAMP8,CXCR4,ITGA2,GPR15,RNASEK,NECTIN2,CAV1,TNFRSF14,CAV2,CTSB,NRP1,MRC1,CD80,VPS18,MOG,F11R,SIVA1,CBL,CCR5,WWP1,CLDN1,IDE,DPP4,NUP153,CD46,CD81,JPT2,PLSCR1,CD4 |
| 4.912e-04 | -7.62 | small-subunit processome | cellular component | GO:0032040 | 73 | 35 | 19108 | 5553 |
RPS27A,RPS9,NGDN,NOL7,RPS5,WDR3,MPHOSPH10,UTP25,NOP58,XRCC5,RPS17,RPS11,RPS24,RPS13,KRR1,UTP15,IMP3,FCF1,RCL1,IMP4,RPS7,RPS23,RPS28,PWP2,RPS4X,UTP6,AATF,NOC4L,PNO1,UTP23,RPS12,RRP7A,EMG1,RPS16,RPS14 |
| 4.913e-04 | -7.62 | protein targeting | biological process | GO:0006605 | 249 | 98 | 18204 | 5365 |
ZDHHC24,GRPEL1,TIMM10,SSR3,GABARAP,UBL4A,AIFM1,ZDHHC4,TOMM22,CLU,TIMM13,SEC63,SRP14,ZFAND2A,GRPEL2,ROMO1,VPS54,TRMT10B,FIS1,BECN1,SEC61B,TIMM8A,NDP,AIP,DNLZ,YWHAB,SEC61A1,TIMM8B,HGS,SPCS1,SYNGR1,TOMM40L,OS9,ATG3,TRAM1L1,SRPRA,ARL6,EDEM1,TIMM23,TOMM20,SQSTM1,MTCH2,HSP90AA1,TOMM70,HSPA8,ADORA1,HSPD1,LARGE1,MGARP,TRAM1,ZFAND6,SSR1,ZFAND2B,SSR2,VPS4A,LAMP2,SYNJ2BP,RTP4,TOMM40,SPCS3,NLGN1,ZDHHC14,PMPCA,SEC61G,YWHAG,IMMP2L,GNPTG,SRPRB,SDCBP,ZDHHC15,DNAJC19,SGTA,CACNG3,TIMM17A,TOMM7,AQP11,TIMM21,GOLGA7B,HOMER3,YWHAZ,TRAM2,SMURF1,SPCS2,HSPA5,SRP72,AGK,TSPO,MTX2,TOMM6,SEC61A2,TIMM29,GOLGA7,CHCHD4,SRP54,FBXO7,SEC62,SAMM50,TRAK2 |
| 4.919e-04 | -7.62 | ARMC8 (armadillo repeat containing 8) | protein interactions | 25852 | 227 | 87 | 19454 | 5460 |
ZMYND19,MAT2A,TUFM,KPNA6,NONO,ATP1B3,UBE2H,PPIG,NCKIPSD,YPEL5,XPOT,CTNNA1,VIRMA,DEK,DCTN4,CDK1,RPA2,HECTD1,GID8,DVL2,GID4,CCDC106,PDHB,MRPL17,TLE1,TCEAL9,MRPS9,STT3A,HACD3,NKAP,MRPS23,STX6,LY6H,JPH4,ATP5PB,EMILIN3,ADAMTS1,NDUFS3,HBP1,CUL3,MRM2,PKP4,LDHB,MTG2,CUTA,CKB,HTRA2,SLC35C1,FAM83B,BMP1,PRDX2,NDUFAF4,PAFAH1B1,LAP3,PPP1CB,PPT1,LCA5,RMND5B,DDX5,STAU1,NDUFS2,RANBP10,MRPS35,DDX50,SPON1,CTNNB1,INSYN1,MRPL18,ARMC8,CBL,GYS1,LILRB4,C1QTNF1,PPIA,EGLN3,CIB3,SOX2,UCK2,NDUFS6,EZH2,HGS,BCKDK,MAEA,MKLN1,PRPS1,IMMP2L,LECT2 |
| 4.921e-04 | -7.62 | purine-containing compound metabolic process | biological process | GO:0072521 | 483 | 176 | 18204 | 5365 |
PPT1,SHMT1,SARM1,NT5C2,GPAM,EPHA2,PPAT,GTPBP1,NDUFA5,ATP5MK,NME2,PDE2A,NUDT9,ELOVL6,CLPX,NPPC,ELOVL1,SLC22A12,NUDT3,CACNB4,GUCY1B1,NDUFB5,ATP5F1D,ENTPD4,G6PD,PDHA1,TPST1,CD38,NUDT12,ACOT8,BPGM,ACAT1,URAD,PTHLH,SDHB,IDO1,GNAI3,NDUFS2,ADK,GMPS,ATP5PB,NUDT4,ELOVL3,MACROD1,NMRK1,FHIT,DLST,NDUFV2,OARD1,PGM1,HSPA8,ACSS2,NME1,NDUFB10,NDUFAB1,MTHFD2L,MPP1,IDH2,PDE4B,ENO2,ATP5MC3,COX11,ABCG2,HACD1,NUDT16,GAPDH,NDUFB4,HINT1,FAR2,ATP5F1E,AK3,SAMHD1,HMGCS1,NDUFS6,SDHC,PDE9A,NQO1,RAN,NDUFB8,PAPSS2,NUDT7,AK5,PGK1,ELOVL4,LIPA,ATP5MG,TTR,PDE1A,UQCC3,RPIA,UCP2,ATP5PD,PRPS1,NUDT2,NPR2,ATP5F1B,OLA1,FMO1,ABHD14B,PGAM1,PDE8A,NDUFA1,LDHA,PFKFB2,FKRP,SULT1A3,PDHB,KDM1A,DNPH1,ACACA,IDH1,DCK,BAD,ADCY2,ATP5MC1,ATP5PF,TECR,MVD,DLG1,ATP1A2,NDUFA2,RPE,TP53I3,ATP1B1,NUDT18,MMUT,SUCLG2,HACD2,DNAJC30,STOML2,ACSL4,FITM2,CASK,FMO2,RAB23,SLC25A1,IER3,ALDH1L1,ENPP4,NDUFB6,ENO1,HTR2A,DLAT,PNP,ATP5F1A,NDUFS8,GLYAT,GPD2,NDUFB7,GNMT,SULT1B1,PDE7A,NDUFA12,ELOVL7,AK2,DCAKD,ADCY3,ATP6V1A,ADSS2,PC,ACOT6,NDUFS3,NME4,NUDT19,LDHB,NDUFC2,MTAP,MFN1,OGDHL,GUK1,PRPSAP1,NUDT5,PCK2,NUDT1,MDH1,ATP5PO |
| 4.925e-04 | -7.62 | AHNAK (AHNAK nucleoprotein) | protein interactions | 79026 | 276 | 103 | 19454 | 5460 |
EEF2,ACTN4,ISG15,RAF1,TOP3B,B3GNT2,MOB3C,DCUN1D5,MTA2,FAM136A,CHMP4C,EZH2,BAG2,UBE3A,PABPC1,HSPD1,S100B,HNRNPDL,RUVBL1,TRIM37,S100A10,LASP1,YWHAH,PDIA3,HSPB1,HNRNPD,MED4,AGR2,ZCCHC9,FOLR1,CACYBP,SUMO2,TANK,CLDN4,MYL6,PIH1D1,PPT1,HSPA8,RNF41,STAU1,OXCT1,EMC1,BTF3,HSD17B3,HNRNPAB,MYC,BRCA1,PHF21A,VDAC2,APEX1,MORC4,EEF1A1,TP53,CCT5,KBTBD4,NUPR1,CAPZA2,EMC2,RPL23A,TOLLIP,HDAC6,USP2,EEF1B2,ITK,CDC5L,TMPO,ARF6,CFTR,COMMD3,CDC42,PCK2,ARL15,METTL14,RPA2,NUDT12,SQSTM1,FLCN,PML,SIRT7,INPPL1,RPA3,BAP1,HSPA5,GRPEL1,FBXW7,HMGB1,CERS2,KDM1A,USP14,GORASP2,H2BC9,ARHGAP21,PYCR2,AKT1,RPF2,UBE2H,TXNIP,RTRAF,ING2,CTTN,VIRMA,DYRK1A,NDN |
| 4.932e-04 | -7.61 | CALCOCO1 (calcium binding and coiled-coil domain 1) | protein interactions | 57658 | 78 | 36 | 19454 | 5460 |
NDC80,CREBBP,CTNNB1,TPM3,PCBD1,FOSL2,FAS,SRP14,ZMAT2,MAP1LC3A,AP2M1,CYTH1,HNRNPL,CEP19,SRPK2,SMURF1,FAM161A,ATG16L1,GABARAPL2,GABARAPL1,MAP1LC3B,ISOC1,IPP,SCHIP1,RNF8,APTX,TBC1D17,SLU7,EP300,SQSTM1,RABGGTB,CRYBA2,CTNNBL1,ENKD1,CA10,GABARAP |
| 4.932e-04 | -7.61 | MFSD14B (major facilitator superfamily domain containing 14B) | protein interactions | 84641 | 78 | 36 | 19454 | 5460 |
EMC6,CSGALNACT2,TMBIM6,ZDHHC24,TMEM208,TMEM19,SLC25A46,FMO1,SLC66A2,CYBC1,TMEM229B,COMT,TECR,FUNDC2,YIPF4,TMEM176A,CLDN4,GOSR2,TIMMDC1,CYB5B,TMEM31,USE1,GRM2,CTSA,ERG28,UNC50,TMX2,SLC39A9,ORMDL1,LRP10,LEPROTL1,FKBP8,SACM1L,TMEM167B,ADIPOQ,DNAJC30 |
| 4.932e-04 | -7.61 | TBC1D10B (TBC1 domain family member 10B) | protein interactions | 26000 | 78 | 36 | 19454 | 5460 |
KRAS,RIGI,STX7,UBE2A,RPA3,ZYX,PMAIP1,FGFR1,RPA2,TBK1,RAF1,GABARAPL1,RHOJ,ARF6,CAV1,APEX1,STX6,DIRAS3,SYNCRIP,RAB35,LMBR1L,HRAS,MAP1LC3A,H2AC4,RHOB,LAMTOR1,YWHAB,BRD3,NTRK3,MYC,DPP4,RAB2A,CISH,YWHAG,LAMP3,YWHAH |
| 4.951e-04 | -7.61 | RFC3 (replication factor C subunit 3) | protein interactions | 5983 | 164 | 66 | 19454 | 5460 |
CUL3,SLC25A1,MYC,MCM3,BTF3,RFC5,TRIM23,RIT1,UBE2H,ZBTB38,CCNF,LMBR1L,PTEN,TRIM29,ESR2,RPL10,TANK,TPT1,ATG16L1,KLRD1,HCST,GABRA1,CDC42,RFXANK,RPA2,HECTD1,HEXIM1,RPA3,RFC4,EP300,RNF113A,HSPA8,UFL1,NF2,HSCB,WWP2,IFI16,UBXN6,DDRGK1,SNRNP70,H2AC4,SPPL3,FZR1,CDC5L,SURF6,CDK9,TP53,ARFGAP1,RAF1,ZNF263,TULP3,EZH2,RAD1,RNF8,MOB3C,FAF1,PICK1,PCNA,H3C1,KRAS,TNFSF8,G3BP1,SSRP1,RAD21,RFC2,MEPCE |
| 4.951e-04 | -7.61 | RHOBTB2 (Rho related BTB domain containing 2) | protein interactions | 23221 | 164 | 66 | 19454 | 5460 |
ETF1,DUSP14,BRIX1,SRSF2,TRA2B,NSFL1C,STK38,MCMBP,TXNL1,RAB9A,DDX39B,XPOT,STK11,EPHA2,RPS26,HSP90AA1,CCT2,MYO6,DEPDC1B,PSMD1,PRPF31,CFL2,RHOBTB3,MLF2,RPF2,RAB2A,SLC25A1,COPS7A,HNRNPC,CUL3,MAD2L1,VIRMA,TMOD3,GANAB,RPS12,MACROH2A1,NEFL,PRKAG1,PPP2R1A,APBB3,MCM6,PSMD12,PAK6,FLOT1,COPS4,SSRP1,NEDD8,CDC40,CSE1L,RAB1A,TOP2B,SSX2IP,SLC2A1,COPS5,PPM1D,TPM3,CACYBP,PPIA,CCT7,HSP90AB1,TOP1,COPS2,H2AZ1,PTPN1,AIFM1,STT3A |
| 4.956e-04 | -7.61 | positive regulation of immune response | biological process | GO:0050778 | 640 | 227 | 18204 | 5365 |
TNFAIP3,SHLD1,RAB29,EIF2B3,KLK5,EP300,NFKBIA,CLPB,FCN2,TGFB2,KARS1,NCR3,CCR7,TLR6,KLK3,STAT6,CREBBP,PTPN22,DHX9,C1QC,IL1B,MIR136,LACC1,LTA,FOSL2,PRKCE,PRKCB,FCGR1A,OAS1,TRAF3IP3,TLR7,IRF7,NLRP6,JAK2,STX7,TIRAP,PLA2G5,IFI35,BECN1,IL2,PAK2,UBE2N,KLRD1,CRKL,CNR1,LAT2,XBP1,TNFSF13,CD14,BAX,SPG21,RSAD2,CSK,IL6,CD86,FOXP1,STOML2,CCL5,POLR3B,UBE2K,FGR,TLR3,FCER1G,IL12B,IL6ST,BTN2A2,HSP90AA1,USP15,IRF3,FLOT1,PELI1,RNF34,CD79B,SASH3,IL12A,FOXP3,CD274,HSPD1,BCL10,LILRB1,MATR3,POLR3F,CD28,CD36,CD80,MEF2C,NCR3LG1,MAD2L2,CAV1,IFNB1,TYROBP,RIGI,SIN3A,CLEC6A,TAB1,MAVS,VAV2,NMI,RC3H2,LILRA2,CD46,LCP2,CD4,MIR21,CD81,PSEN1,IFIH1,IFNK,TLR9,SOCS5,RTN4,MYD88,SH2D1A,IL4,RGCC,TESPA1,KLRC2,PIK3AP1,TRAF2,KMT5B,TRIM62,RPS3,TRIM6,LY96,YES1,TFRC,PHB1,TNF,SLC39A10,CACNB3,XCL1,IL10,FCGR2B,PYCARD,HRAS,STK11,CD226,TRIM5,STAP1,HMGB1,CD1D,CLU,SYK,MBL2,NLRP1,HFE,CD40,OTULIN,KCNJ8,CACNB4,NFKB1,CGAS,TASL,MAP2K6,LSM14A,PSPC1,SPHK2,CCR2,TIFA,TLR5,CCL19,XRCC5,TBK1,CYRIB,PLSCR1,TMEM126A,MAPKAPK3,CTLA4,NINJ1,CD38,CD2AP,NLRP3,TRAF6,TLR2,CD1B,TICAM2,TLR10,CD1C,CLEC7A,IL21,NEK7,IL17F,PIK3CA,CD1E,IDO1,IFNG,SPPL3,PHB2,MICB,TOMM70,HEXIM1,THY1,CD1A,NONO,NECTIN2,PDE4B,TLR4,PLPP4,IL18,SRC,HSPA8,IL23A,B2M,ITK,EIF2B2,ATAT1,MOG,EXOSC3,TLR1,HMCES,IL15,TICAM1,RBCK1,IKBKB,TRIM15,LIPA,IFI16,TLR8,EIF2B5,CD247,ZNRF1,CD3G,TRIM3,SLA2,PRKCQ,PQBP1,IRAK4 |
| 4.963e-04 | -7.61 | soft_tissue-fat-liposarcoma | COSMIC cancer mutations | soft_tissue-fat-liposarcoma | 26 | 16 | 16828 | 4835 |
IDH1,KRAS,HRAS,SF3B1,EWSR1,NFE2L2,STK11,SS18,AKT1,JAK2,CTNNB1,TP53,DICER1,EZH2,PIK3CA,TERT |
| 4.968e-04 | -7.61 | L-glutamate import across plasma membrane | biological process | GO:0098712 | 11 | 9 | 18204 | 5365 |
CLN8,GRM1,SLC1A1,SLC1A2,SLC7A11,KCNJ10,ARL6IP5,PSEN1,SLC1A3 |
| 4.981e-04 | -7.60 | SYNJ2BP (synaptojanin 2 binding protein) | protein interactions | 55333 | 126 | 53 | 19454 | 5460 |
GP9,CDC42,SYNGR2,FAM234A,TOMM22,TOR1AIP2,DAD1,ABCC2,ADRB2,VIPR1,P4HA2,MGAT4B,TSPAN15,ZMPSTE24,ATP1B3,ARHGAP19,CYB561,FCER1G,TOMM40,GPBAR1,SLC7A8,PRDX2,ACTB,REEP4,SYNGR1,S1PR4,OPTN,SCAMP2,DIO2,HGS,TMEM14B,CYB5B,OTULIN,TFRC,RELL2,ACTN4,TMEM101,FLOT1,ELOVL7,AKAP14,PRPSAP1,SLC2A1,PROM1,ESYT1,KARS1,EGLN3,TLCD4,WIF1,SLC25A12,PRNP,TSC22D3,THY1,STARD3NL |
| 5.012e-04 | -7.60 | Histone_H2A_C | interpro domains | IPR032454 | 17 | 12 | 18521 | 5414 |
H2AZ2,H2AC1,H2AC14,H2AJ,H2AZ1,H2AC6,H2AC25,H2AX,H2AC4,MACROH2A2,MACROH2A1,H2AC7 |
| 5.020e-04 | -7.60 | GLMN (glomulin, FKBP associated protein) | protein interactions | 11146 | 170 | 68 | 19454 | 5460 |
DET1,HCST,FKBP1A,KLC2,EIF4B,MET,RNF7,RPA2,VIPR1,BIRC2,APPBP2,HCFC2,IRF3,RPA3,SKP1,PIP4P1,RP2,NSFL1C,FBXW7,STAU1,KDM1A,TMEM213,GPR17,CUL2,CUL3,DTL,DCAF16,DCAF4,AMIGO1,ANAPC2,NEGR1,CMTR1,LMBR1L,CCNF,APLNR,TAX1BP1,MGST3,LPAR6,ACTR1A,TMEM126A,CYB5B,POC1B,TMEM88,RUSF1,PTGES3,PPDPF,FEM1C,FEM1B,P2RY10,CDC37L1,SAV1,HSPB1,CDKN1B,TMEM164,DCAF11,FKBP4,FXYD6,CRBN,SMAD4,KRT8,ST6GAL1,EGLN3,DIRAS3,LMAN1,DYNC1I2,KCTD10,CAND1,GFOD1 |
| 5.020e-04 | -7.60 | MRTO4 (MRT4 homolog, ribosome maturation factor) | protein interactions | 51154 | 170 | 68 | 19454 | 5460 |
RC3H2,RHOB,FTSJ3,UBE2H,RIT1,DNAJB6,CDKL2,NSA2,MYC,CUL3,CUL2,RAB11A,ZNF622,RHOJ,RPL10,ESR2,SRPK2,RSL24D1,CCNF,EIF2AK2,RPL37A,EIF2S2,CDK1,RPA2,MACROH2A2,BET1,UFL1,STAU1,FBXW7,BRIX1,RPA3,RPL27,PML,SIRT7,MTDH,EP300,CCDC86,WDR12,SNRNP70,LHX2,RPL10A,GRSF1,DPP4,IFI16,XPO1,DDRGK1,CAND1,CGAS,KLF9,ZBTB2,KRR1,XPO5,CHMP4C,HBP1,MTMR2,FURIN,NUPR1,RAF1,E2F4,MAGEB10,SUPT5H,SOX2,ISG15,KRAS,RIGI,RPL31,RAB27A,RPL23A |
| 5.030e-04 | -7.59 | protein transporter activity | molecular function | GO:0140318 | 39 | 22 | 18094 | 5411 |
TIMM17A,TOMM22,TOMM20,TOMM40,AZGP1,LMBRD1,SEC61G,TOMM7,TIMM8B,TOMM40L,IGF1R,GPIHBP1,SEC61A2,BLOC1S3,TOMM70,SEC61A1,ATAD1,SEC63,PEX13,MCL1,TIMM23,TIMM29 |
| 5.033e-04 | -7.59 | innate immune response activating cell surface receptor signaling pathway | biological process | GO:0002220 | 67 | 33 | 18204 | 5365 |
SYK,MBL2,TLR2,CD14,SRC,TRAF6,MYD88,TICAM2,IRAK4,LILRA2,PAK2,TLR5,IRF3,TBK1,KLRD1,CREBBP,TLR4,TMEM126A,NFKBIA,EP300,TYROBP,TICAM1,CLEC6A,FCN2,IKBKB,TIRAP,NMI,KLRC2,PRKCE,PIK3AP1,CLEC7A,OAS1,LY96 |
| 5.036e-04 | -7.59 | BUD13 (BUD13 homolog) | protein interactions | 84811 | 106 | 46 | 19454 | 5460 |
NLE1,KIN,RPL4,RPS14,FGF13,PAK2,RPLP0,RPL26L1,EZH1,PRKRA,RPL37A,FGFBP1,RBMX2,RPL13A,SPCS1,SNRNP40,RPL19,ESR2,SRPK2,APEX1,MYC,RPL7A,RPL31,SNIP1,RPL3,H1-6,SRSF4,RPL28,MTA3,H2AJ,MAP2K3,CDK8,MTA2,RPL18,RPL8,SRP14,TOP1,LYAR,SURF6,CDC5L,IFI16,DDX23,NOL12,BRD3,RPL10A,ANKRD50 |
| 5.046e-04 | -7.59 | WDR6 (WD repeat domain 6) | protein interactions | 11180 | 270 | 101 | 19454 | 5460 |
RC3H2,STK11,NCKIPSD,EPHA2,UBE2H,RAB2A,FBXO7,TIA1,ATP5F1A,DNAJC5,RHOJ,SMURF1,PSPC1,CCNF,PPM1M,RPA2,SAMM50,ZNF574,OXSR1,WDR5B,CDC42,KDM1A,PIK3R2,FTSJ1,CDC42EP4,HSPA5,RHOU,RPA3,SIRT7,RAB9A,DNAJC7,STYK1,NFKB1,EDEM1,COPS5,LAMP3,ARF6,RPS16,LMAN1,EPHB6,CAV1,RNF128,RAC2,TFCP2,JCHAIN,MTCH2,MAP1LC3B,TGFBR2,FAF1,NTRK2,LAMTOR1,BRCA1,RHOB,NTRK3,ILK,MYC,GRB10,RAB11A,CUL3,DYNLL1,RPL10,PAPSS2,PHF21A,BET1,RND2,UFL1,STAU1,STX7,PSMC1,HSPA8,RAB5A,RHOG,HAX1,DYRK1B,PIK3R1,LAMP2,RAB5C,WWP2,ATG7,DDRGK1,COPS7B,RHOH,G2E3,EGLN3,DIRAS3,COX14,HSP90AB1,RAB35,PHB1,GJA1,KRT8,COPS2,RND3,RAF1,JUN,EPHA4,KRAS,CDK20,PSMD12,COPS4,FLOT1 |
| 5.048e-04 | -7.59 | RARA (retinoic acid receptor alpha) | protein interactions | 5914 | 173 | 69 | 19454 | 5460 |
HNRNPA0,HDAC3,GTF2I,NRBF2,MBD3,CCND3,RFC4,SMARCD3,PML,HSPA8,SQSTM1,PRDX6,EP300,PPARG,FGFR1,H2AC1,PRKCA,MACROH2A2,PRMT2,CDK7,SIAH1,SNRNP40,NR1H2,CBX5,LRIF1,GADD45G,SRC,PSPC1,PSMC5,TRIM24,FAS,TADA3,H2AZ2,SP1,CREBBP,AKT1,TRIM32,RUNX1,ZBTB16,TRIM37,HNRNPK,RUVBL1,RPS27A,H2AC6,TRIP4,GADD45A,TOP2B,RBM3,PIK3CG,UBE3A,EZH2,BTG1,MTA2,ANP32A,ACTN4,MECR,PLEKHF2,MDM2,FABP5,RXRG,SMAD3,MRTO4,COPS2,SNRNP70,HSPB1,PIK3R1,HMGA1,HR,SUV39H1 |
| 5.048e-04 | -7.59 | LSR (lipolysis stimulated lipoprotein receptor) | protein interactions | 51599 | 173 | 69 | 19454 | 5460 |
LAMP2,RAB5C,LAMP3,YWHAH,YWHAG,SMAD4,RHOG,TMEM30A,YWHAB,SMAD3,RAB35,HRAS,GJA1,RNF128,RAC2,SPINT2,MARCHF4,ARF6,PRNP,RHOH,DIRAS3,EPHB6,STX6,CAV1,RPN1,RND3,NTRK2,EPHA4,KRAS,RAB3B,TGFBR2,CD1B,FLOT1,RAB2A,SFN,RAB11A,PCDHB1,H2BC9,DNAJC5,LAMTOR1,HFE,RHOB,YWHAZ,AP2A1,NTRK3,MARCHF3,CCNF,LMBR1L,GGT7,SYNE4,RHOJ,ESR2,SMAD5,CLDN4,MAPKAPK5,ATG16L1,TMEM231,BET1,RND2,CDC42,MED23,FGFR1,CHRNB2,RPA3,RHOU,RAB5A,NUP50,RAB9A,STX7 |
| 5.070e-04 | -7.59 | MACF1 (microtubule actin crosslinking factor 1) | protein interactions | 23499 | 209 | 81 | 19454 | 5460 |
AGR2,RHOG,YWHAB,CAMSAP2,RPL6,MOV10,EXOC1,YWHAH,YWHAG,CSNK2A1,PRNP,HNRNPL,CAV1,CDC5L,DIRAS3,STX6,TNIK,SYNCRIP,RAB35,TES,RAC2,GJA1,CHMP4C,DISC1,DNAJC2,CAPZA2,CBX3,NUPR1,DHX38,SNAP29,JUN,SOX2,SNAPIN,WASL,HUWE1,G3BP1,KRAS,FLOT1,RIGI,MEPCE,ZYX,PPP1R12A,PDIA6,ABCE1,RHOB,PKNOX1,YWHAZ,CCT2,UBE2H,MAPRE1,CUL3,SFN,MYC,TUFM,USP14,DNAJC5,ST13,SNRPB,ACTB,RHOJ,ATP5F1B,SRPK2,VIRMA,ESR2,MAD2L1,CTNNA1,PPP2R5E,GSK3A,RPA2,HEXIM1,TMOD1,CFTR,STAU1,FBXW7,CSRP1,SIRT7,RPA3,RHOU,DVL2,BAP1,RAB5A |
| 5.086e-04 | -7.58 | FGD5 (FYVE, RhoGEF and PH domain containing 5) | protein interactions | 152273 | 206 | 80 | 19454 | 5460 |
CFTR,PPP1CB,RPS14,MYL6,MET,KRT7,HADHA,ARPC2,HSPA8,SPECC1L,HSPA5,EEF1G,STAU1,PHB2,GTF2I,TUFM,MCM3,ATP5F1A,PRKACB,PSMD1,RPL7A,LDHB,HSP90AA1,MYO6,CCT2,GNPDA1,ALB,ACAT1,RTRAF,ENO1,ENO2,TUBA1B,ARF1,RPS3,TUBB,ACTB,PSMD6,TMOD3,LDHA,PRDX2,ATP5F1B,COPE,EEF1A1,TUBA1A,ACTN4,RPSA,CCT5,CBX3,TUBB4B,HSD17B10,IGF1R,MYO1B,SEPTIN7,PCNA,CCT8,PABPC1,PALM2AKAP2,HSPD1,PPP1R12A,FLOT1,RPS4X,KPNA2,ETFA,GAPDH,SUV39H1,RPL6,FCGR1A,MAP4,RPS2,PSMD7,KRT8,HSP90AB1,CCT7,MYL12A,RPL7,TCP1,PRNP,SPTAN1,AGK,EIF2S1 |
| 5.086e-04 | -7.58 | ITPR3 (inositol 1,4,5-trisphosphate receptor type 3) | protein interactions | 3710 | 206 | 80 | 19454 | 5460 |
PHB2,DUSP26,SGF29,PXMP2,RAB29,SIRT7,BAP1,RPA3,DERL1,RAB9A,MTDH,AKAP1,COMMD2,SIGMAR1,STX17,SSR1,RPA2,ATG16L1,ST7,CDC42,SEC62,OTULINL,SEC63,VIRMA,ESR2,LMBR1L,TACO1,SEC61B,PTEN,CSNK2B,LMNB1,RAB11A,AKT1,BTF3,TESPA1,VDAC1,CAMK2G,FKBP8,PSMB10,TMT1A,CYP2C9,CAPZA2,CHMP4C,KRIT1,ACTR2,RAB4A,RPN1,TFRC,STIM1,NUPR1,RPS11,RAF1,TOP3B,SNAP29,FGL2,DNAJC25,DNAJC1,CAV1,LMAN1,PTPN1,KRT8,RAC2,HSD17B11,GJA1,BECN1,ESYT1,TRPC1,RHOG,PEX3,DNAJC7,TNNC2,RB1CC1,POU5F1,AHSA1,SLC25A46,MARCHF5,RAB5C,LAMP2,CCR6,LAMP3 |
| 5.090e-04 | -7.58 | LUC7L3 (LUC7 like 3 pre-mRNA splicing factor) | protein interactions | 51747 | 179 | 71 | 19454 | 5460 |
UBE2H,RIT1,NLRP3,PTTG1,ZBTB38,DCAF4,TXNIP,PPP1CC,AR,SNRPB,CUL3,CUL2,MYC,SRPK2,SNRNP40,TXN,SNRPD2,PHAX,SMU1,ENO1,CCNF,TRMT112,LUC7L3,GRM2,RPA2,LMNA,ELK4,FBXW7,NF2,UFL1,RNF113A,CLK1,BANF1,RPA3,BAP1,SNRPA,TLR10,SNRNP70,DDX23,DDRGK1,COPS5,YWHAG,WWP2,MOV10,H2AC14,ZBTB2,DYNC1I2,KCTD10,PAIP1,CAND1,HNRNPL,EED,PHB1,SRSF1,FOLR1,ZRANB2,MTMR2,SKA3,PPP2R1A,RAF1,TBK1,FBP1,B3GNT2,RIGI,MEPCE,S100A10,RBBP7,KRAS,SRSF7,TRIM11,RUVBL2 |
| 5.111e-04 | -7.58 | UBE2L3 (ubiquitin conjugating enzyme E2 L3) | protein interactions | 7332 | 200 | 78 | 19454 | 5460 |
HERC3,FOS,HELLS,BAP1,SOD1,PTRHD1,BIRC2,UCHL3,HSCB,RNF11,PIAS1,TPT1,PCK2,CDC42,RNF182,RNF7,RNF103,WWP1,PITPNA,PIH1D1,HECTD1,RTF2,NFKBIA,STUB1,MRPL53,VDAC2,CCNF,PTEN,TRAF7,SNX12,NDFIP1,SNX3,HECW1,IRF2BP1,SMURF1,UBE2V2,UBE2L3,UBB,SUGP1,MYC,BAG3,BRAP,TRIM23,BRCA1,ANKIB1,HERC4,UBE2H,UBE3A,TRIM21,RBCK1,SRPRB,HSPE1,PSMA5,KRAS,HUWE1,UFM1,AHCYL1,RNF20,UBE2A,TP53,MAP1LC3B,MMACHC,UBE2B,PIR,EZH2,EIF4E2,HEBP1,RNF144B,ESD,MDM2,WWP2,RNF14,TRAF6,SMAD4,MUL1,CDKN1B,AREL1,CBL |
| 5.115e-04 | -7.58 | PLRG1 (pleiotropic regulator 1) | protein interactions | 5356 | 185 | 73 | 19454 | 5460 |
PRPF19,IFI16,WWP2,XPO1,DDRGK1,SNRNP70,KPNA1,MAGOH,RPL9,MIR106B,SRSF1,PHB1,FZR1,SNRPD3,SNRPA1,MIRLET7G,TOP1,CDC5L,CWC15,RAF1,E2F4,CD2BP2,JUN,EZH2,PDHA1,ILF2,NUPR1,SNIP1,PABPC1,KRAS,TSSC4,CTNNBL1,BACH1,KPNA2,SSRP1,MDC1,MYC,CUL3,RNF40,SNRPB,AR,ZCRB1,RC3H2,UBE2H,CCNF,EIF4A3,DLST,SNRPD1,SNRPD2,GSK3A,AP2M1,SF3B4,SNRNP40,FBXO22,SNRPB2,ESR2,SF3A1,MX1,ZSCAN1,RPA2,LSM2,SNRPA,RPA3,MIR205,PRPF4,MIRLET7I,SF3B1,HSPA8,EP300,SRSF2,UFL1,MRPL40,STAU1 |
| 5.124e-04 | -7.58 | NDUFV2 (NADH:ubiquinone oxidoreductase core subunit V2) | protein interactions | 4729 | 191 | 75 | 19454 | 5460 |
IMMP2L,FASTKD5,VDAC1,DNAJC30,EMC2,HINT2,HAPSTR1,NDUFA4,SFXN1,HSPD1,NDUFB5,GFM2,NDUFA12,NDUFS3,NDUFS6,METTL15,AURKAIP1,NDUFA2,MRPL11,STK3,NPC2,NDUFS8,UQCRH,TMED9,NDUFA1,GATD3,CORO1C,COX4I1,NDUFB4,SSBP1,AIFM1,SYNCRIP,SDHB,NDUFB8,MRPS26,TMEM70,CHCHD1,POR,RHOG,STK4,GRSF1,MTRF1,CRYZ,HSCB,NDUFS2,PDHB,NPTN,NDUFC2,GFM1,EXD2,NGRN,SLC25A3,CYC1,MTRES1,ARMCX3,UQCRC1,NOTCH2,PARL,SUCLG2,CCDC90B,TACO1,LMBR1L,DNAJC19,HTRA2,CRMP1,TUFM,HMOX2,PMPCA,NDUFB10,NDUFB6,MTG2,NDUFB7,CSK,NDUFAF2,AUH |
| 5.151e-04 | -7.57 | synaptic signaling | biological process | GO:0099536 | 459 | 168 | 18204 | 5365 |
GABRB3,NPY,PPP3CA,WNT7A,SLC6A1,GNB1,KCND2,AKT1,CDK5,STX1A,GABARAP,LIN7B,PLG,STX11,IL1RAP,CHRDL1,DRD3,SLC6A3,RIMS4,CACNB3,HRH2,PPT1,NSG1,CRHBP,SLC1A1,CTNNB1,HRH3,RAP1A,DBH,SLC1A2,ASIC1,NPR2,GABRG2,KCNMB1,SNAP23,INSYN2B,SCN2B,UTS2,GHRL,GRIA1,NLGN2,TNR,GNAI2,GLRB,GRM2,SLC29A1,VPS54,NAPA,CBLN1,RNF10,RIC3,PDYN,CARTPT,DLG1,CNR1,CRKL,RAB3A,NPTX1,LYNX1,DLG3,CHRM1,SYPL1,VAMP2,USP14,PTEN,STXBP1,GLRA2,GPR176,GAD2,RIT2,TMOD2,ASIC2,DRD1,GUCY1B1,KCNJ8,KCNIP2,GSK3A,CPLX2,PRKCB,CHRM3,CACNB4,PRKCE,GRID1,PLP1,NPY5R,GNA11,EXT1,GABBR1,COMT,PDLIM4,SST,ADORA1,STAC3,CPLX3,LARGE1,DAG1,HTR2A,GRIK1,HTR1F,VDAC1,HOMER1,GRM1,CHRM5,SNAP29,OPRM1,CDK5R1,DLG4,PMP22,SLC1A3,SNAP25,FGF12,CACNB2,PPFIA3,PAFAH1B1,SDCBP,NPBWR1,FCHSD2,TAC1,RIMS3,HTR5A,GLRA1,KPNA1,NLGN1,HCRT,SNCB,SLC6A2,LY6H,CHRM4,SLITRK5,PNOC,GNAQ,CNP,GABRA1,SYT2,MPZ,PLCB1,GABRB2,NQO1,SNCG,RGS10,DNAJC5,CPLX1,SV2B,CBLN2,LIN7C,GRIA2,OPRK1,SYT4,NTRK2,CLSTN3,INSYN2A,GJC1,PSEN1,PCDHB13,ACHE,GABRA2,TPBG,HTR1A,MECP2,SNAPIN,SLC32A1,MEF2C,DRP2,INSYN1,CHRNB2,EZH2,SYN3,CHRNA7 |
| 5.154e-04 | -7.57 | EDRF1 (erythroid differentiation regulatory factor 1) | protein interactions | 26098 | 92 | 41 | 19454 | 5460 |
ANAPC2,MAB21L1,FBXO31,FKBPL,EEF1AKMT3,HSP90AB1,IRF2BP1,TTC9C,AIPL1,YWHAH,YWHAG,EXOC5,DNAJC5,UBXN6,MLF1,TBCE,NDC80,CUL2,HSP90AA1,BAX,MED4,CDC23,DNAJC7,BCL2L1,CHORDC1,LAMTOR1,HSPA8,BAG2,SQSTM1,DCTN3,LTO1,PFDN1,ZDHHC17,TUSC2,RIGI,CDK20,TTC4,TMEM266,NEK2,GEMIN7,GSTO2 |
| 5.164e-04 | -7.57 | PFKP (phosphofructokinase, platelet) | protein interactions | 5214 | 264 | 99 | 19454 | 5460 |
PGRMC1,RND2,PIH1D1,DDX39B,HSPA8,EEF1G,MCMBP,CUL3,CDKN3,MYC,RHOB,BRCA1,ILK,NTRK3,LMBR1L,GTF2F1,DYNLL1,CAVIN2,ESR2,TOP3B,RAF1,TNPO2,TUBA1A,SOX2,FAF2,CHMP4C,TUBB4B,VPS33A,EZH2,RNF126,MTA2,AKT2,RPL31,TRIM21,KRAS,WDR19,AHCYL1,PIK3R1,MAPK4,NT5C2,YWHAG,PPIB,AGR2,DUSP6,RPLP2,RHOH,SUMO2,ARHGAP1,CCND1,ATG16L1,CDC42,FGFR1,RPA2,OXSR1,MET,SIRT7,BAP1,DVL2,RPA3,ARFIP1,SQSTM1,RNF113A,SYVN1,FBXW7,CRYZ,AKT1,AKT3,CCDC22,UBE2H,NRP1,ATP1A1,ZBTB38,TUBA1B,GAB1,CCNF,PHAX,CTSB,MGST3,DYRK1A,VIRMA,TBK1,EEF1A1,MAP1LC3B,FURIN,IGF1R,HAPSTR1,THRAP3,TOLLIP,FBXO25,DPP4,COPS5,CD81,HDAC6,EID1,STYK1,DNAJC7,PRNP,CDC5L,TMPO |
| 5.192e-04 | -7.56 | TGFBRAP1 (transforming growth factor beta receptor associated protein 1) | protein interactions | 9392 | 54 | 27 | 19454 | 5460 |
NRBF2,TICAM1,VPS16,ACVR1B,TGFBR2,SEMA4C,BMPR1A,LTO1,VPS33A,ACVR1,RNF7,VPS18,TMEM266,ARFGAP1,LRRC61,ESR2,VIRMA,HNRNPL,TTC9C,S100A6,MID1IP1,RPL32,SMAD2,CSTA,SMAD4,PSMD14,ATG9A |
| 5.192e-04 | -7.56 | ZFYVE19 (zinc finger FYVE-type containing 19) | protein interactions | 84936 | 54 | 27 | 19454 | 5460 |
DPY30,SFN,YWHAZ,UBE2D1,VPS4A,CCHCR1,IGBP1,DSTN,TYMS,PRNP,TTC9C,G6PD,UBE2V2,UBA52,UBE2B,VPS4B,PAK2,TTC1,TRIM63,CHMP1B,UFM1,UCHL3,RIGI,AHCYL1,VTA1,ZDHHC17,UBE2A |
| 5.198e-04 | -7.56 | Glutathione_S-Trfase_N | interpro domains | IPR004045 | 28 | 17 | 18521 | 5414 |
CLIC2,GDAP1L1,GSTM4,GSTT1,GSTM5,CLIC4,GSTT2B,HPGDS,GSTM3,GSTP1,GSTA4,GSTO1,GSTA2,EEF1G,GSTM2,GSTO2,GSTA1 |
| 5.208e-04 | -7.56 | FKBP9 (FKBP prolyl isomerase 9) | protein interactions | 11328 | 70 | 33 | 19454 | 5460 |
GRPEL1,HSPA5,PHB2,XPNPEP1,NUBP2,NDUFC2,TMEM106B,FKBP10,APEH,STOM,CDC42,GTF3C4,MGARP,EHD1,UBR7,ATP5PB,HEXA,ACTB,KCTD10,PRNP,PRCC,PHB1,PDCD10,RPL23,HERC4,CASC3,H2AZ2,ATP5F1A,DAG1,API5,MYC,COX5A,FAM20C |
| 5.208e-04 | -7.56 | SIK3 (SIK family kinase 3) | protein interactions | 23387 | 70 | 33 | 19454 | 5460 |
CCT5,ISG15,CRTC2,PPP3R2,TIMM8A,TAB2,CCT8,HDAC5,ARPC2,RNF113A,CMAS,PTGES3,SFN,YWHAG,YWHAH,CCT2,YWHAZ,HSP90AA1,SMAD2,YWHAB,PPP3CA,OSBPL8,STUB1,SMAD3,OCIAD2,PRNP,TCP1,CACYBP,EGLN3,CCT7,TRAF1,VIRMA,HSP90AB1 |
| 5.208e-04 | -7.56 | RIOK3 (RIO kinase 3) | protein interactions | 8780 | 70 | 33 | 19454 | 5460 |
RUVBL2,RPS24,TRIP4,RPS28,PNO1,RPS4X,FBXO25,RPS27A,RPS15,UBIAD1,CDC42,TULP3,RPS7,PSMC4,RPSA,RPS11,PAK2,RPS20,PSMB1,RPS3,KRR1,SMURF1,RPS16,NOB1,RPS10,RPS17,ZMAT3,XPO1,MOV10,MYC,TM9SF4,RPS26,RPS2 |
| 5.208e-04 | -7.56 | SHOC2 (SHOC2 leucine rich repeat scaffold protein) | protein interactions | 8036 | 70 | 33 | 19454 | 5460 |
TPPP,JUP,DISC1,SHOC2,RAF1,TPT1,PPP1CB,HUWE1,KRAS,FBXW7,OLA1,PRPS1,PGK1,IDH1,EP300,RIT1,HSPB1,MAPRE1,YWHAB,MYC,ATG7,GLO1,TUFM,PPP1CC,PNP,ESR2,G6PD,OPTN,HRAS,MRAS,PSMC5,TRIM27,USP46 |
| 5.208e-04 | -7.56 | K8.1 (K8.1) | protein interactions | 4961469 | 70 | 33 | 19454 | 5460 |
CHCHD6,SYNGR1,SLC39A10,COX4I1,SLC38A2,UQCRQ,RALA,EXOC1,EXOC5,NDUFV2,MGST2,NDUFB10,NDUFB8,OSBPL8,EXOC2,LAMTOR1,TMEM11,COX8A,SYVN1,PIP4P1,HIGD2A,GTF2I,ERLEC1,UQCRC1,ASPM,GTF3C4,FUT8,MTX2,MTCH2,PIP4P2,FAM8A1,SAMM50,COX6C |
| 5.221e-04 | -7.56 | CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4) | protein interactions | 131474 | 132 | 55 | 19454 | 5460 |
SSR1,CDR2,OXSR1,UBE2M,UBA52,TIMM10,PHB2,OXCT1,HSCB,STX7,NDUFC2,RAB9A,UBE2H,RIT1,TXNRD2,GRB10,NDUFB7,COX6B1,MYC,VPS39,RPL10L,ATP5F1B,TXN,NDUFAF4,SLC25A31,ZNF518B,VPS72,ENO2,ACOX1,GXYLT1,CTU1,DTYMK,COA5,DDX39A,APOO,ZNF581,SSNA1,CHCHD2,KRAS,PSEN1,SFXN1,TMX3,IDH1,MED29,CHCHD1,PEX3,PPFIBP1,NKAP,RPS10,SLC25A12,UQCRH,CDR2L,CCDC127,AIFM1,SDHB |
| 5.221e-04 | -7.56 | SUDS3 (SDS3 homolog, SIN3A corepressor complex component) | protein interactions | 64426 | 132 | 55 | 19454 | 5460 |
KLF9,SHPRH,BRMS1L,LDLR,GATAD1,MYBL2,EED,H2AZ1,SIN3A,KPNA1,CSNK2A1,ZCCHC10,MDC1,GTF3C3,MRPL22,PHF1,KRAS,RBBP7,SRSF7,KLF10,TGIF2,RHOBTB1,MTA2,HBP1,EZH2,SAP30,ING1,AURKAIP1,ZNF704,PHF23,MTA3,MAX,RBBP4,GTF2F2,PTEN,ING2,CSNK2B,PHF12,SP1,HSP90AA1,LMNB1,BRMS1,AR,SMARCA5,HNF1B,HSPA5,MBD3,LDOC1,SAP18,TGIF2LX,EP300,RNF113A,HSPA8,LACC1,MXD1 |
| 5.221e-04 | -7.56 | BAX (BCL2 associated X, apoptosis regulator) | protein interactions | 581 | 132 | 55 | 19454 | 5460 |
SLC25A46,BAK1,PRDX1,COPS5,HDAC6,SMAD4,YWHAB,BCL2L1,ARL10,GTF2B,MCL1,RNF144B,TP53,PSMC3,SH3GLB1,HSPD1,HSD17B10,SEPTIN7,VDAC1,USP30,GUK1,ANP32B,MEPCE,GSTK1,SFN,BAG3,TOMM40,UBE2H,SERPINH1,BAX,ANAPC4,KCNA3,LIG3,LMBR1L,BAD,PSMC5,SLC25A4,PRDX2,ESR2,VIRMA,TOMM22,MAP2K1,FGFR1,CRYAB,PRSS23,XRCC5,BAP1,RPA3,AKAP1,PMAIP1,NSFL1C,HSCB,BNIP3L,CLU,BCL2A1 |
| 5.233e-04 | -7.56 | Histone_H2A_C | pfam domains | PF16211 | 17 | 12 | 17795 | 5224 |
H2AC25,H2AZ1,H2AX,H2AJ,H2AC1,H2AC14,H2AZ2,H2AC7,H2AC4,H2AC6,MACROH2A2,MACROH2A1 |
| 5.237e-04 | -7.55 | S1PR1 (sphingosine-1-phosphate receptor 1) | protein interactions | 1901 | 109 | 47 | 19454 | 5460 |
RER1,CMTM6,VPS28,CERS6,ATP2C1,TMEM160,HTR1A,IRF3,TSPAN15,RAP2A,STX17,TM9SF1,CD47,TNPO3,B4GAT1,ACP2,SRC,RMDN3,CHCHD6,COX16,ATP1A3,TMED5,AKT1,CNNM4,SACM1L,TMED1,GNG5,GNAI3,TSPAN3,GNAQ,TMEM126A,IPO8,YIPF3,ZMYM3,TNPO2,CAV1,HRAS,ARL10,SLC39A10,MCL1,TSG101,FAM241B,PPM1B,CMSS1,SYNJ2BP,WWP2,GOLPH3L |
| 5.237e-04 | -7.55 | SKIC2 (SKI2 subunit of superkiller complex) | protein interactions | 6499 | 109 | 47 | 19454 | 5460 |
RPA2,EXOSC4,SNAPC1,RHOU,RPA3,FBXW4,SIRT7,STAU1,SNRPB,TTC33,PMPCA,CDC73,PFDN4,PFDN2,PFDN6,UBE2H,PTPMT1,PSPC1,LMBR1L,IRF2,RAN,PELO,RPL10,DUSP10,ESR2,VIRMA,FBXO22,MGARP,LGR4,HBP1,SRP72,SRSF7,PFDN1,MAP3K14,UBXN6,FAM174A,PFDN5,WWP2,SKIC8,CACNB3,TES,ALYREF,CDK9,CCT7,SPPL3,RPS16,CGAS |
| 5.315e-04 | -7.54 | CAND2 (cullin associated and neddylation dissociated 2 (putative)) | protein interactions | 23066 | 81 | 37 | 19454 | 5460 |
EFNB1,CD83,CXCR4,BAP1,SEMA4C,NPTN,SEC62,NPY2R,CHRM3,FAM234A,NAA15,ADORA3,STOM,SDC2,SIGLECL1,TMEM108,CHRM4,PSMA6,LMBR1L,SCN2B,CCNF,S100A6,DNAJC1,VTI1B,DDRGK1,SLAMF9,COPS5,DLK2,P2RY10,GPR17,FAM174A,CUL3,CIDEB,DRG1,DNAJB6,UBE2D1,SYP |
| 5.323e-04 | -7.54 | RPL3L (ribosomal protein L3 like) | protein interactions | 6123 | 62 | 30 | 19454 | 5460 |
RPL8,CCNF,RPL9,RPS9,RPS20,RPL37A,RPL7,RPS16,RPL19,RPL7A,RPL6,RPL39,FBXO7,RPL24,RPL23,RPS26,RPS2,RPL27,TERT,RPL3,RPL23A,RPL4,G3BP2,RPL27A,RPL15,CHMP4C,RPS23,RPL18,MTMR2,ILF2 |
| 5.323e-04 | -7.54 | ZFYVE27 (zinc finger FYVE-type containing 27) | protein interactions | 118813 | 62 | 30 | 19454 | 5460 |
GPR17,CUL3,RAB2A,ZFAND2B,ATP5F1A,YES1,TNFSF18,SPPL3,ATP5F1B,ACP2,ATP5PD,SLC66A2,GOLGA5,TMEM184B,PIP4P2,SLC19A2,ATP5PB,SYNGR2,SEC62,SEC22A,DHX16,SACM1L,STX7,TSPAN15,ORMDL1,TMT1A,TMEM243,DERL1,YIF1A,ATP5IF1 |
| 5.323e-04 | -7.54 | ARHGAP19 (Rho GTPase activating protein 19) | protein interactions | 84986 | 62 | 30 | 19454 | 5460 |
DCAF16,YWHAZ,CIRBP,SERPINH1,YWHAB,HAX1,FHIT,SFN,SYNJ2BP,MRPL16,YWHAH,YWHAG,PRNP,ATP5PD,CPSF1,SSBP1,HACD3,GANAB,RPA2,SURF4,SNRPE,PGRMC1,IKZF5,LBR,DDX39A,RBBP7,RNF41,SFXN1,DVL2,ATP5IF1 |
| 5.323e-04 | -7.54 | GCH1 (GTP cyclohydrolase 1) | protein interactions | 2643 | 62 | 30 | 19454 | 5460 |
PPM1B,YWHAZ,ARMC8,AHSA1,CNRIP1,ATP1B1,CSNK2A1,TNPO3,EIF2AK2,ZNHIT6,MID1IP1,RPS12,CALML5,CSNK2B,EIF2B3,GIT2,GCHFR,ARHGAP1,PIP5K1A,RRM1,TNPO2,MAPK10,PACSIN3,RANBP10,RGS19,GID8,MAEA,GID4,SQSTM1,HSPA8 |
| 5.323e-04 | -7.54 | DIP2B (disco interacting protein 2 homolog B) | protein interactions | 57609 | 62 | 30 | 19454 | 5460 |
APEX1,ESR2,VIRMA,ACTB,RHOJ,SUMO2,HNRNPL,RAB35,MAPRE1,UBE2H,NRP1,NTRK3,RHOB,LAMTOR1,YWHAH,PTGES3,RAD21,FLOT1,FKBP8,EPHA4,KRAS,SLC31A1,SQSTM1,CNKSR3,EIF1AD,FGFR1,RPA2,TULP3,ATG16L1,ARFGAP1 |
| 5.329e-04 | -7.54 | TARS2 (threonyl-tRNA synthetase 2, mitochondrial) | protein interactions | 80222 | 135 | 56 | 19454 | 5460 |
HNRNPL,RMND1,LRRC61,EGLN3,COX4I1,PHB1,AIFM1,SSBP1,GATD3,FAHD1,SNRNP70,RHOG,AHSA1,HAX1,DNAJC7,CBR4,DDRGK1,RASL10B,KRAS,MRPS17,SYPL1,HSPD1,SLC25A10,HINT2,PDHA1,TULP3,ESR2,APEX1,CCNF,FKBPL,LMBR1L,ANAPC2,CHORDC1,LAMTOR1,UBE2H,CUL3,MTG2,AUH,TUFM,STAU1,HSCB,AMACR,THUMPD1,EXD2,RPA3,MAIP1,AKAP1,GRM2,RPA2,QRSL1,NUDT12,LDHAL6B,MTRES1,WDR83,CFTR,CNPY3 |
| 5.349e-04 | -7.53 | CCR3 (C-C motif chemokine receptor 3) | protein interactions | 1232 | 22 | 14 | 19454 | 5460 |
CCL5,CCL11,CCL28,CCL3,CCL24,PRKCA,FGR,FAM241B,CCR3,CXCL10,CCL8,CXCL11,CXCL9,CCL2 |
| 5.349e-04 | -7.53 | FAP (fibroblast activation protein alpha) | protein interactions | 2191 | 22 | 14 | 19454 | 5460 |
RBM3,PHB1,THY1,CORO1C,PHB2,SPPL3,HUWE1,CAV1,CSK,MYC,MSRB1,DPP4,ERLIN2,STOM |
| 5.349e-04 | -7.53 | NACA2 (nascent polypeptide associated complex subunit alpha 2) | protein interactions | 342538 | 22 | 14 | 19454 | 5460 |
BCAP29,PCNA,RPL32,PTGES3,RPS13,TUFM,BTF3L4,BTF3,ISYNA1,TOP3B,TPD52,CALR,RPL23,CALU |
| 5.349e-04 | -7.53 | NAA20 (N-alpha-acetyltransferase 20, NatB catalytic subunit) | protein interactions | 51126 | 22 | 14 | 19454 | 5460 |
SWAP70,NHEJ1,REG1A,AKAP1,KRAS,MARS1,SMAD5,SCML2,CACYBP,ADIPOR1,NAA15,IKBKB,CIRBP,RIT1 |
| 5.349e-04 | -7.53 | SDHD (succinate dehydrogenase complex subunit D) | protein interactions | 6392 | 22 | 14 | 19454 | 5460 |
TNNC2,RIT1,RPA2,IL17F,GPR35,HBB,PPIL3,SRC,RPA3,TBC1D24,SDHB,BAP1,SDHC,SPECC1L |
| 5.352e-04 | -7.53 | Toll-Like Receptor Pathway 1 | SMPDB pathways | SMP0063899 | 34 | 23 | 1369 | 531 |
TAB2,TLR3,TOLLIP,TLR7,EIF2AK2,TRAF6,MAP2K6,JUN,PPARA,CD14,NFKBIA,TLR2,LY96,TLR4,TAB1,NFKB1,TIRAP,MAP2K3,MYD88,IKBKB,ELK1,TLR9,FOS |
| 5.352e-04 | -7.53 | negative regulation of ERK1 and ERK2 cascade | biological process | GO:0070373 | 75 | 36 | 18204 | 5365 |
MIR185,DUSP3,EPHA4,CRYBA1,MIR200C,MIR133B,NHERF1,ADIPOQ,DUSP6,NLRP6,SPRED1,MIR424,TBC1D10C,SPRED2,PHB1,SYNJ2BP,CSK,GSTP1,FLCN,PTPN1,MIR205,TLR9,CNKSR3,MIR21,TLR4,DUSP10,SMAD4,DLG1,BTN2A2,DUSP26,SPRY1,EMILIN1,ATF3,MIR221,MIR503,LMO3 |
| 5.386e-04 | -7.53 | purine ribonucleotide biosynthetic process | biological process | GO:0009152 | 180 | 74 | 18204 | 5365 |
PDHA1,SDHC,ATP5PF,GUK1,NDUFC2,TECR,NDUFS6,AK5,LIPA,SDHB,ELOVL4,ATP5PO,ACAT1,NDUFA2,PAPSS2,NDUFB8,NDUFB4,ATP6V1A,ADCY3,ADSS2,NPPC,AK2,ELOVL7,HACD1,ELOVL6,DCAKD,GUCY1B1,NME4,ADCY2,ATP5MC1,ATP5F1D,NDUFB5,NDUFS3,ACACA,ELOVL1,AK3,ATP5F1E,NDUFAB1,NDUFB10,ATP5F1A,NME1,PPAT,NDUFA1,NDUFS8,ACSS2,DLAT,ATP5MC3,NDUFA5,NDUFB7,NME2,PDHB,ATP5MK,COX11,NDUFA12,DNAJC30,ACSL4,STOML2,ATP5PB,UQCC3,ELOVL3,ATP5MG,PPT1,GMPS,HACD2,NDUFS2,ADK,MMUT,ATP5F1B,NDUFV2,NPR2,NDUFB6,SLC25A1,ATP5PD,NUDT2 |
| 5.398e-04 | -7.52 | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | 38 | 21 | 16828 | 4835 |
SS18,EWSR1,NFE2L2,HRAS,KRAS,KLF4,IDH1,FGFR1,TERT,PIK3CA,CDH11,PTEN,EZH2,KIT,RB1,MET,CTNNB1,TP53,JAK2,ETV6,AKT1 |
| 5.406e-04 | -7.52 | response to xenobiotic stimulus | biological process | GO:0009410 | 429 | 158 | 18204 | 5365 |
EMX1,LIPA,EPHX1,HADH,AOX1,TXNRD2,CDKN1B,CYP2D6,GSTO2,RBM22,RAP2A,NQO1,ABCC2,SLCO1A2,TSPO,UBE2B,GSTO1,GUK1,GSTA1,CYP2C18,BLOC1S3,GSTA4,GSTA2,MEF2C,SLC6A4,NFE2L2,PAX6,AKR1C1,CBR3,TXNIP,VAV2,CRYZ,SULT1B1,HSP90AA1,OXSR1,PRNP,VEGFC,EMX2,CYB5B,SLC1A3,GLYAT,PDE4B,CYP2F1,TENT4A,SLC6A11,PNP,SST,UGT1A1,CMBL,COMT,PPP1R12A,KCNJ11,CYP26A1,CDK1,ERRFI1,HSPA8,HTR2A,REN,ADRA1A,SRC,SLITRK5,CREB1,SFRP1,MYC,SLC6A2,TRAF3IP2,POR,GNPAT,BGLAP,SOD2,MDM2,ABCC5,GSTM3,KCNC1,FMO2,MYO6,HADHA,TP53,TLR3,TGFBR2,BECN1,SLC29A1,SS18,CCND1,CDK4,CRKL,CYP2C8,UMPS,SOD1,CYP1A1,XRCC5,GRIA1,GSTM4,CD38,AIP,CYP1B1,FZD3,SLCO1B3,SLCO2B1,HDAC5,PRKCB,KCNJ8,DRD1,ASIC2,LTA,FOSL2,RB1,OGG1,TYMS,SLC22A12,DUSP6,FOS,TOP1,NPPC,MAP2K6,CDKN1A,NR1I2,GAD2,CYP2C9,STAT1,CXCR4,FBP1,NKX3-1,SEMA3C,DRD3,ITGA2,AMELX,FKRP,SULT1A3,CYP3A5,CYP4F12,GCLC,IL1B,GSTM2,FMO1,BAK1,ATP1A1,MAP1B,SLC1A2,PCNA,GSTP1,NAT2,CTNNB1,CYP2R1,RHBDD3,CRHBP,SLC1A1,TFRC,OXTR,RPP21,GPX1,TNF,ADIPOQ,SLC6A3,DPEP1,IL10,CALR,ABCB1 |
| 5.421e-04 | -7.52 | adult behavior | biological process | GO:0030534 | 146 | 62 | 18204 | 5365 |
DBH,SLC1A2,GABRG2,SLITRK5,HEXA,CRHBP,SLC1A1,HOXB8,CNP,PPP1R1B,PCDH17,SLC7A11,PAFAH1B1,NTF4,PPT1,KCNJ10,EPHA4,GLRA1,HOMER1,LEP,CEND1,FKRP,DRD3,FGF12,OPRM1,EPS8,PPARA,BRS3,NPY,TBCE,CDK5,HTR2A,CXCL12,DRD1,NCSTN,CACNB4,CRHR1,CHRNB2,TUBA1A,SLC6A4,CLN8,NR4A2,MECP2,SLITRK1,USP46,KLHL1,ARCN1,CSTB,GRM2,FXN,OPRK1,MAFG,ATP1A2,CARTPT,ZMPSTE24,GHRL,HTRA2,TMOD1,SNCG,ABHD12,GLRB,NLGN2 |
| 5.429e-04 | -7.52 | PDE3B (phosphodiesterase 3B) | protein interactions | 5140 | 112 | 48 | 19454 | 5460 |
DERL1,RAB9A,TEX264,LRRTM2,PXMP2,ST7,CDC42,SEC62,OTULINL,SSR1,SEC61B,LMBR1L,CD79B,SEC63,VIRMA,AKT1,AKT3,YWHAZ,TLR9,TMT1A,CYP2C9,FKBP8,LRP3,SRPRB,LGR4,TMEM59,DNAJC25,RPN1,STIM1,RAC2,HSD17B11,RAB35,KCNA2,PTPN1,ANKRA2,TMPO,EGLN3,LMAN1,HNRNPL,MARCHF4,DNAJC1,YWHAG,LRRTM1,YWHAH,HPGDS,YWHAB,LRRC8B,RHOG |
| 5.429e-04 | -7.52 | ITPR2 (inositol 1,4,5-trisphosphate receptor type 2) | protein interactions | 3709 | 112 | 48 | 19454 | 5460 |
LMAN1,DNAJC1,HSD17B11,GJA1,PTPN1,TNNC2,HAX1,TRPC1,CCR6,LAMP3,SLC25A46,RIGI,FKBP8,NUP107,CAMK2G,CYP2C9,TMT1A,PSMC3,RPN1,CAPZA2,SOX2,DNAJC25,CA8,TOP3B,MAD2L2,ESR2,VIRMA,SEC61B,TESPA1,BTF3,RAB11A,GPR17,PXMP2,SGF29,LPAR1,RAB9A,DERL1,RAB29,PML,P2RY12,SSR1,CDC42,SEC62,OTULINL,CNPY3,ST7,ATG16L1,TPRA1 |
| 5.430e-04 | -7.52 | APOB (apolipoprotein B) | protein interactions | 338 | 138 | 57 | 19454 | 5460 |
HSPA8,SYVN1,TACR1,DERL1,MIA2,FADS2,SLC5A6,HSPA5,LITAF,RER1,TMEM167B,TMEM184B,P2RY12,HSP90B1,SEC61A1,SYNGR1,GPR173,SEC61B,SCAMP2,CYB5R3,STUM,B4GAT1,CKLF,ELOVL3,MLF1,MYC,HSP90AA1,LRP6,PSMD14,TRIM23,B3GALT2,AKT2,PRDX4,PAX6,RAD21,FAF2,YIPF3,RAF1,ARFGAP1,TBK1,TOP3B,TRIM6,CRKL,GJA1,LDLR,SMAD3,HRAS,MDM2,TMPO,SPTAN1,PPIB,DPP4,CALR,CD36,SELENOS,TMEM208,SEC61A2 |
| 5.430e-04 | -7.52 | NOL9 (nucleolar protein 9) | protein interactions | 79707 | 138 | 57 | 19454 | 5460 |
RPA2,H2AB1,NPM3,HSCB,STAU1,SNAPC1,BAP1,RPA3,PML,SIRT7,HSPA8,SQSTM1,PSKH1,ATG3,DNAJB6,RIT1,MYC,CUL3,RANBP6,KCTD9,SNRNP40,RBBP4,PPP5C,SRPK2,ESR2,PSPC1,PELP1,CCNF,ZNF330,MACROH2A1,SPIN3,HBP1,RAF1,TP53,JUN,AURKAIP1,SOX2,KRAS,CHCHD2,PTGES3,IMMP2L,SNIP1,RPL31,RPS24,DNAJC7,RPS2,HAX1,IFI16,NFKB1,XPO1,ATG7,DDRGK1,SPPL3,SUMO2,EGLN3,ZBTB2,KIAA0232 |
| 5.435e-04 | -7.52 | TRIM24 (tripartite motif containing 24) | protein interactions | 8805 | 386 | 138 | 19454 | 5460 |
SPOP,IGF2BP1,DNAJC19,RBM7,AKT1,MAT2A,CDC16,ATF4,NTAQ1,MTPN,AR,NONO,RPS3,ZNF330,EIF4A3,LURAP1,CMBL,ALB,UBE2I,TRIM24,PTEN,MACROH2A1,RPA2,RPRD1B,HSP90B1,METTL14,MACROH2A2,STAT6,SPTBN1,SUMO1,MYL12B,AGO1,GTF2I,NUCKS1,SOD1,CSTB,PML,PGK1,PPIH,NR1I3,CDK12,KXD1,CALR,PGAM1,GTF2E1,TPM3,RPS16,MIF,TOP1,PRNP,CDK9,SMAD3,SYNCRIP,CBX3,NFE2L2,SOD2,ILF2,RNF181,TNRC6C,TP53,EGR2,H3C1,HSPE1,ZNF287,GARRE1,DHX9,CKB,TFDP2,LMNB1,BRCA1,NLRP3,MDH1,SYCE3,CREBBP,HNF1B,MYC,CUL3,HNRNPC,MCM4,GGH,TAGLN2,MATR3,TAB1,SNRNP40,MAD2L1,CBX5,ESR2,TAF11,RNF141,APEX1,VPS72,ZMYM2,KLF3,PPARG,ELF5,MFAP1,MYL6,NUP62,STAU1,TRIM52,DDX39B,SNRPA,PEBP1,RPS28,FOS,XRCC5,SF3B1,EP300,UBE2D1,GSTO1,HSPB1,LHX2,TAF7,PDIA3,TRIM8,PADI2,PPIB,XPO1,PGR,SPTAN1,SUMO2,DHX15,NPC2,NUP35,FABP5,MARCKSL1,VDR,SOX2,ELF1,TRIM37,ASF1A,RPS4X,RPS27A,MCM6,SSRP1,PAX6,SLC25A5,PDIA6 |
| 5.436e-04 | -7.52 | NME3 (NME/NM23 nucleoside diphosphate kinase 3) | protein interactions | 4832 | 95 | 42 | 19454 | 5460 |
PLD3,RPA2,PRKAG1,SSR1,NME1,PTRH2,TUBA1A,EHD1,DUSP22,HTR2A,TOMM22,MTCH2,TOMM20,NME4,FXR2,HSCB,DESI1,HSPA8,NUBP2,AKAP1,TTC8,DUSP9,RPA3,SFXN1,EXD2,NRP1,UBE2H,BBS5,NME2,CHCHD4,UBB,COX14,PLGRKT,ESR2,MGST3,SLC25A4,TUBB,XPO5,SFXN2,SGTA,CCNF,DUSP6 |
| 5.439e-04 | -7.52 | GST_N | pfam domains | PF02798 | 15 | 11 | 17795 | 5224 |
GSTM3,GSTM4,GSTA4,GSTA1,GSTP1,GSTT2B,GSTA2,HPGDS,GSTM2,EEF1G,GSTM5 |
| 5.440e-04 | -7.52 | Oxidative phosphorylation | KEGG pathways | ko00190 | 120 | 59 | 7161 | 2463 |
NDUFB10,NDUFB6,NDUFV2,ATP6V1G1,CYC1,UQCRH,ATP5F1B,COX6C,COX10,ATP5F1D,COX7A1,NDUFA5,COX4I1,ATP6V0E1,SDHB,UQCRC2,NDUFC2,COX5A,COX7B2,COX6B1,ATP5MC3,ATP5F1E,NDUFA2,NDUFB4,ATP5PB,ATP5PF,COX6A2,ATP5MC1,NDUFS2,NDUFB7,UQCR11,ATP5MG,ATP6V1A,ATP5F1A,UQCRQ,NDUFA1,NDUFS8,COX11,ATP6V1G2,COX4I2,UQCRC1,COX6B2,COX7B,ATP6V1C1,NDUFB5,NDUFA4,ATP6V1E2,NDUFA12,COX17,ATP6V0B,NDUFAB1,ATP6V1D,NDUFS6,COX8A,NDUFB8,SDHC,ATP5PO,ATP5PD,NDUFS3 |
| 5.440e-04 | -7.52 | Oxidative phosphorylation | KEGG pathways | hsa00190 | 120 | 59 | 7161 | 2463 |
NDUFB7,UQCR11,ATP5F1A,ATP6V1A,ATP5MG,UQCRQ,NDUFA1,COX6A2,ATP5MC1,NDUFS2,UQCRC1,COX6B2,NDUFS8,COX11,ATP6V1G2,COX4I2,NDUFB5,ATP6V1C1,NDUFA12,ATP6V1E2,NDUFA4,COX7B,ATP5PO,SDHC,NDUFS3,ATP5PD,ATP6V0B,COX17,NDUFAB1,NDUFS6,COX8A,ATP6V1D,NDUFB8,NDUFB6,NDUFV2,ATP6V1G1,UQCRH,CYC1,NDUFB10,COX7A1,NDUFA5,COX4I1,ATP5F1B,COX6C,ATP5F1D,COX10,COX7B2,COX6B1,UQCRC2,SDHB,ATP6V0E1,COX5A,NDUFC2,ATP5PF,ATP5MC3,ATP5F1E,NDUFA2,NDUFB4,ATP5PB |
| 5.446e-04 | -7.52 | dendritic cell chemotaxis | biological process | GO:0002407 | 17 | 12 | 18204 | 5365 |
CCR5,CXCR1,HMGB1,CCL21,CCL5,PIK3CG,CCR6,CCR7,CCR2,CCL19,CCR1,CXCR4 |
| 5.446e-04 | -7.52 | regulation of amyloid fibril formation | biological process | GO:1905906 | 17 | 12 | 18204 | 5365 |
MIR31,USP8,PFDN5,LDLR,PFDN6,PFDN4,PFDN1,CLU,PFDN2,CHRNA7,PSEN1,CRYAB |
| 5.470e-04 | -7.51 | TICAM2 (TIR domain containing adaptor molecule 2) | protein interactions | 353376 | 29 | 17 | 19454 | 5460 |
FTH1,TIRAP,NTAQ1,TRAF6,TLR3,SMAD4,IRF3,BMPR1A,TLR4,SARM1,BSCL2,JAK1,IRF7,IL1RAP,IRAK4,TICAM1,TICAM2 |
| 5.488e-04 | -7.51 | cellular response to topologically incorrect protein | biological process | GO:0035967 | 83 | 39 | 18204 | 5365 |
RPAP2,OS9,KLHL15,CAV1,NFE2L2,UBE2W,VAPB,DERL1,ERLEC1,RNF126,BAX,EIF2S1,OPTN,CDK5RAP3,BAK1,ERO1A,DERL2,SDF2L1,EIF2AK2,PTPN1,HSPD1,BAG3,TMBIM6,XBP1,UFD1,CREBZF,HSPA5,CUL3,DNAJC10,STUB1,ATF4,HSPB8,CREB3,SELENOS,DDIT3,ATF3,CCND1,PACRG,HDAC6 |
| 5.490e-04 | -7.51 | organophosphate biosynthetic process | biological process | GO:0090407 | 533 | 192 | 18204 | 5365 |
GPHN,HMGCS1,AK3,ATP5F1E,HEXB,CMPK1,NDUFB4,SACM1L,FABP5,RRM1,HACD1,ELOVL4,SLC52A3,LIPA,PIGY,AK5,PAPSS2,NDUFB8,TAMM41,PGS1,PTDSS1,BPNT2,PIK3R1,SDHC,PIK3R2,NDUFS6,SLA2,HDHD5,SLC30A5,PIGK,NDUFV2,SERINC1,PGAP4,GNPAT,ELOVL3,NMRK1,PIGC,ATP5PB,PIK3CA,IDO1,GMPS,NDUFS2,ADK,FIG4,COX11,INPP4A,ATP5MC3,IP6K1,VAC14,SORD,PIK3CG,MTHFD2L,NDUFB10,TMEM38B,NME1,MTMR2,NDUFAB1,ACSS2,NDUFB5,ATP5F1D,TAFAZZIN,THTPA,PIGA,GUCY1B1,TYMS,ELOVL1,PTPMT1,INPPL1,NPPC,SPHK2,UCK1,ELOVL6,DCTD,PIP4K2C,SDHB,ACAT1,PLSCR1,UMPS,SGMS2,NUDT12,PDHA1,SELENOI,G6PD,CHKB,GPAM,PLAAT3,SHMT1,UCKL1,PPT1,GPAA1,ATP5MK,NME2,ABHD5,NDUFA5,DPM2,FITM1,ORMDL3,PPAT,GK2,CISH,PCYT1B,ACP6,PIGW,NME4,NUS1,NDUFS3,ADSS2,ATP6V1A,ADCY3,SOCS3,DCAKD,ELOVL7,AK2,ATP5PO,OCRL,LPCAT3,DTYMK,SLC19A2,SRD5A3,MTM1,ORMDL1,SOCS5,PRPSAP1,NDUFC2,GUK1,MTMR6,NDUFB6,AGPAT1,CDIPT,PGAP3,SLC25A1,SOCS2,FITM2,ACSL4,STOML2,DNAJC30,MMUT,HACD2,ABHD4,SOCS4,NDUFA12,NDUFB7,IMPA2,UPRT,UCK2,NDUFS8,GGPS1,PNP,ATP5F1A,ISYNA1,INPP5K,AGPAT5,DLAT,SLC25A10,AKR1A1,ATP5MC1,ADCY2,SLC19A3,DCK,ACACA,CKB,PIP5K1A,PTEN,BECN1,HYCC2,NDUFA2,ETNK2,MVD,DHRS7B,PNPO,DOLK,TECR,ATP5PF,ATP5F1B,NPR2,HYCC1,PRPS1,INPP5E,NUDT2,PGAP2,ATP5PD,PLSCR3,UQCC3,SGMS1,PIK3R3,CRYL1,OSBP,KARS1,GK5,ATP5MG,PDHB,NDUFA1 |
| 5.500e-04 | -7.51 | MAP2K3 (mitogen-activated protein kinase kinase 3) | protein interactions | 5606 | 246 | 93 | 19454 | 5460 |
FZR1,CDK9,MAP2K6,EEF1AKMT3,SMAD3,DCK,TES,CDK6,BECN1,RPL24,HNRNPK,AKAP12,HUWE1,DHX9,RPL3,TP53,RPSA,CDK4,SMAD1,MAP2K3,MAP3K3,SRPK2,CTNNA1,TUBA1B,CTTN,CCNF,PTEN,PLCB2,UBE2H,EPHA2,PDCD4,STK11,FOXA3,AKT1,RPL4,NF2,NPM3,HSPA5,MET,TPT1,CDC42,KDELR2,RPL7,HNRNPL,ELK1,PPP2CB,PDAP1,HSPB1,UBXN6,DYRK1B,CTNNB1,ATG7,RUVBL1,CDK20,RBBP7,IMMP2L,RPL28,CDKN2C,HSPD1,SLC25A5,RUVBL2,CTNNA2,TUBB4B,EIF1AX,CCR1,SUPT5H,RAF1,PPP2R1A,RPL29,RBBP4,TUBB,RPL19,MAD2L2,APEX1,POLR2B,MAD2L1,APLNR,YWHAZ,HSP90AA1,KLK5,RPS26,CUL3,SFN,MYC,BTF3,STAU1,HSCB,RPS28,DDX5,TERT,HSPA8,FOXS1,SLC25A3 |
| 5.523e-04 | -7.50 | NDUFA6 (NADH:ubiquinone oxidoreductase subunit A6) | protein interactions | 4700 | 141 | 58 | 19454 | 5460 |
HSCB,SLC25A51,CRYZ,NGRN,RPA3,EXD2,HSPB2,GFM1,NDUFC2,MTRES1,UQCRC1,TIMM29,TOM1L2,ATP5F1B,LMBR1L,TACO1,CCDC90B,NRP1,CSK,AUH,COX6B1,MTG2,PMPCA,TUFM,DNAJC30,FASTKD5,IMMP2L,HSPD1,NDUFA4,HINT2,COX8A,PDHA1,NDUFS6,NDUFS3,GFM2,NDUFA12,OTULIN,MRPL11,MTCH2,AURKAIP1,METTL15,NDUFS8,COX14,RMND1,SDHB,SSBP1,PHB1,COX4I1,FAHD1,GATD3,NDUFA1,RHOG,CHCHD1,TMEM70,MRPS26,MTRF1,GRSF1,NDUFV2 |
| 5.523e-04 | -7.50 | ZC3H4 (zinc finger CCCH-type containing 4) | protein interactions | 23211 | 141 | 58 | 19454 | 5460 |
FBXO22,RPL13A,IFI6,SNRNP40,VIRMA,EZH1,CSNK2B,CFAP298,PDCD4,PEA15,MYC,CUL3,ANAPC15,PPP1CC,TUFM,SNRPB,AR,PSENEN,STAU1,AIF1,BAP1,SNRPA,EP300,RNF113A,NUP50,SQSTM1,RPA2,EHHADH,SHMT1,CAPN1,CDC42,NEK7,FZR1,HNRNPL,TOP1,MIF,PTP4A3,WDR82,SNRNP70,BRD3,UQCR11,ANKRD50,ZNF24,HNRNPA1,CSNK2A1,ERLEC1,PSMA2,H3C1,SSRP1,RIGI,DPM2,SLC25A10,MRPS11,EZH2,CBX3,FURIN,TMEM14B,SUPT5H |
| 5.529e-04 | -7.50 | regulation of protein localization to membrane | biological process | GO:1905475 | 183 | 75 | 18204 | 5365 |
AGR2,STX8,CLIP3,PRNP,GPC4,SQSTM1,LZTFL1,GPC1,HRAS,TMBIM1,CDK5R1,RANGRF,ZDHHC8,KCNJ11,PDCD5,AKT2,CDK5,EPHA2,VAMP8,STAC3,INPP5K,DAG1,AKT1,RAP1A,CSK,EFCAB7,TCAF2,SLC1A1,HPCA,TNFAIP6,MIEF1,VPS4A,SLC7A11,PGRMC1,MIR223,FRRS1L,KCNB1,PIK3CA,TNF,ACTB,SPTBN1,IFNG,DPP10,MMP14,CHP1,FIS1,ARF6,CD81,DLG1,CRKL,TMEM59,STOM,ATP2C1,PICALM,AR,PIK3R2,PIK3R1,RHOG,PID1,NLGN2,PPP2R5A,NGDN,CPLX1,PRKCE,CNPY4,RAMP3,LYPLA1,AP2M1,VTI1B,RER1,ATP2B4,LGALS3,BCL2L1,STX7,NETO2 |
| 5.541e-04 | -7.50 | very long-chain fatty acid biosynthetic process | biological process | GO:0042761 | 13 | 10 | 18204 | 5365 |
ELOVL7,HACD1,ELOVL1,HACD3,HACD2,TECR,ELOVL6,ELOVL4,ELOVL3,HACD4 |
| 5.541e-04 | -7.50 | positive regulation of glial cell migration | biological process | GO:1903977 | 13 | 10 | 18204 | 5365 |
P2RY12,CX3CR1,CCR2,CCL3,TIAM1,MIR221,CX3CL1,CRKL,MIR222,RRAS2 |
| 5.541e-04 | -7.50 | early endosome to Golgi transport | biological process | GO:0034498 | 13 | 10 | 18204 | 5365 |
TRAPPC10,EHD3,TMED9,RAB6A,LMAN1,STX10,SNX2,SNX1,STX5,SURF4 |
| 5.556e-04 | -7.50 | MCM4 (minichromosome maintenance complex component 4) | protein interactions | 4173 | 283 | 105 | 19454 | 5460 |
ACTR1A,H2AX,TP53,ILF2,GINS4,NECAP1,HAPSTR1,HSD17B10,MAP1B,DUSP19,RIGI,H3C1,HUWE1,KPNA2,COPS5,ORC5,MOV10,USP15,H2AC4,RB1,CD274,CDC5L,TOP1,MAPRE2,MIF,GTF3C4,CFTR,SF3A1,ING5,HEXIM1,UBE2M,MACROH2A2,LMNA,RPA2,DCTN4,CDK1,HSP90B1,METTL14,ORC6,SOD1,INPPL1,RPA3,BAP1,SIRT7,MBD3,BCL6,SMC4,NUCKS1,CAP2,FOXA3,ZBTB38,UBE2H,IVNS1ABP,GANAB,TRIM24,CCNF,NMI,VIRMA,SRPK2,NUP153,MOB3C,RNF126,EZH2,H2BC1,PCNA,ACTR1B,MCM6,SSRP1,PAK6,RAD21,G3BP1,KRAS,ASF1A,HMGA1,IFI16,DDX23,FKBP4,PHB1,EGLN3,SUMO2,DUSP22,MAP2K1,HSPA8,SF3B1,HDAC5,CRY1,EP300,FBXW4,UFL1,STAU1,MCMBP,MCM4,MCM3,MYC,CUL3,PYCARD,H1-1,MCM8,BRCA1,LMNB1,FBXW11,CDC7,NCKAP1,MATR3,SNRNP40 |
| 5.609e-04 | -7.49 | PPP2R5D (protein phosphatase 2 regulatory subunit B'delta) | protein interactions | 5528 | 144 | 59 | 19454 | 5460 |
DCUN1D5,SH3GLB1,PPP4C,PPME1,FBXL3,PLS3,EZH2,PPP2R1A,SOX2,CSNK1E,FEN1,DUSP19,PTGES3,BAG2,SLC39A7,PSME1,YWHAB,DDRGK1,PPP2R5A,PFDN5,ATG9A,PRDX1,WIF1,SNX1,SPPL3,RPL35A,LHFPL2,YBEY,PPP2CB,CSNK1A1,ACACA,HECTD1,TMOD1,RPA2,TANK,PGRMC1,HAND2,STAU1,ARPC2,SQSTM1,CRY1,RPA3,CCHCR1,BICD2,NIF3L1,GPR17,HNRNPC,DHPS,GPR37,MAT2B,RAPGEF5,PRDX2,MSN,CSNK2B,FAM43A,LURAP1,LMBR1L,CCNF,OPTN |
| 5.609e-04 | -7.49 | RAB3GAP1 (RAB3 GTPase activating protein catalytic subunit 1) | protein interactions | 22930 | 144 | 59 | 19454 | 5460 |
SEC61B,CCNF,LMBR1L,KTI12,PELO,SEC63,COPE,REEP3,GABPA,MYC,SUB1,COP1,FIS1,FLCN,RAB5A,DERL1,RAB9A,RPA3,RCCD1,UPF3B,PXMP2,TACR3,YIPF5,RND2,OTULINL,SEC62,ST7,PSMC4,RPA2,VAPB,SSR1,FGFR1,MAP1LC3A,HSD17B11,TES,PTPN1,SRP14,FEZ1,LMAN1,RAB39B,EGLN3,TMPO,DNAJC1,RAB22A,TSEN34,RAB5C,SLC25A46,SNRNP70,ESYT1,IGF1R,GALNT12,TMT1A,FKBP8,MSH6,DNAJC25,MAP1LC3B,TULP3,STIM1,RPN1 |
| 5.611e-04 | -7.49 | HMG20B (high mobility group 20B) | protein interactions | 10362 | 115 | 49 | 19454 | 5460 |
XPO1,RBM17,USP15,LHFPL4,SRSF1,NKX3-1,SIN3A,HMG20A,DHX15,SNRPA1,SNRPD3,HNRNPL,ZMYM3,SNAPC5,MTA3,SNRPE,RBPJ,MTA2,SF3B5,SMNDC1,ERP29,HSPD1,PAX6,RBBP7,SNRPB,AR,CCDC85B,FBXO7,HNF1B,PHF21A,POLR3H,ZMYM2,SNRPD1,SNRPD2,SF3B4,SF3B6,S100A6,SNRPB2,TRAF1,RBBP4,SF3A1,PAX9,TFIP11,E2F6,RNF113A,SF3B1,DDX46,KDM1A,GTF2I |
| 5.611e-04 | -7.49 | DTNA (dystrobrevin alpha) | protein interactions | 1837 | 115 | 49 | 19454 | 5460 |
TUBA1A,CASK,NTRK2,MLC1,HSPD1,FLOT1,DRP2,PSEN1,HNRNPK,KRAS,TPM3,CTNNB1,INSYN1,PDIA3,RIT2,TIAM1,RHOG,SEC23A,KRT8,GJA1,ANXA4,PHB1,RAB35,CAV1,HMG20A,HSP90AB1,STX6,DIRAS3,HNRNPL,NUP62,FGFR1,HSP90B1,RAB30,HSPA8,HSPA5,STX7,SGF29,DNAJC5,RAB2A,RHOB,BRCA1,LAMTOR1,SPOP,SNTA1,CTNNA1,DES,ESR2,ACTB,RPP25L |
| 5.619e-04 | -7.48 | FAHD2A (fumarylacetoacetate hydrolase domain containing 2A) | protein interactions | 51011 | 49 | 25 | 19454 | 5460 |
ZNF287,MPST,POLDIP2,RIGI,BOLA3,HINT2,HMCES,ACAA2,PIR,ANXA7,SOD2,CMPK1,SOX2,MIF,LGALS3,AKR1C2,DBT,HDHD3,DSTN,LCN8,SORD,UBE2H,TST,CFL1,FCGR2A |
| 5.625e-04 | -7.48 | Cytokines and Inflammatory Response | WikiPathways | WP530 | 26 | 18 | 5310 | 1910 |
IL1A,IL2,IL3,TNF,CD4,IL13,CSF2,IL5,IL12B,IL6,IL15,IL4,IFNG,IFNB1,CXCL1,IL1B,IL10,IL7 |
| 5.626e-04 | -7.48 | RNA Polymerase II Promoter Escape | REACTOME pathways | R-HSA-73776 | 47 | 26 | 10285 | 3229 |
GTF2H4,CCNH,POLR2C,GTF2A1,POLR2I,GTF2F1,ERCC3,TAF11,GTF2B,GTF2F2,GTF2A2,TAF9,POLR2G,TAF10,TAF7,POLR2F,POLR2L,GTF2H5,POLR2D,GTF2H2,CDK7,GTF2E1,GTF2E2,POLR2B,TAF2,MNAT1 |
| 5.626e-04 | -7.48 | HIV Transcription Initiation | REACTOME pathways | R-HSA-167161 | 47 | 26 | 10285 | 3229 |
GTF2F1,POLR2I,GTF2A1,CCNH,POLR2C,GTF2H4,TAF11,GTF2B,ERCC3,GTF2H2,POLR2L,GTF2H5,POLR2D,POLR2F,TAF10,TAF7,POLR2G,GTF2A2,GTF2F2,TAF9,MNAT1,TAF2,POLR2B,GTF2E2,CDK7,GTF2E1 |
| 5.626e-04 | -7.48 | RNA Polymerase II HIV Promoter Escape | REACTOME pathways | R-HSA-167162 | 47 | 26 | 10285 | 3229 |
GTF2E1,CDK7,GTF2E2,TAF2,POLR2B,MNAT1,POLR2G,TAF9,GTF2A2,GTF2F2,POLR2F,TAF7,TAF10,GTF2H2,POLR2D,POLR2L,GTF2H5,ERCC3,GTF2B,TAF11,POLR2C,CCNH,GTF2H4,GTF2A1,GTF2F1,POLR2I |
| 5.626e-04 | -7.48 | RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | REACTOME pathways | R-HSA-73779 | 47 | 26 | 10285 | 3229 |
MNAT1,POLR2B,TAF2,GTF2E2,GTF2E1,CDK7,POLR2D,POLR2L,GTF2H5,GTF2H2,TAF7,TAF10,POLR2F,TAF9,GTF2A2,GTF2F2,POLR2G,GTF2B,TAF11,ERCC3,POLR2I,GTF2F1,GTF2A1,GTF2H4,CCNH,POLR2C |
| 5.626e-04 | -7.48 | RNA Polymerase II Transcription Initiation | REACTOME pathways | R-HSA-75953 | 47 | 26 | 10285 | 3229 |
MNAT1,POLR2B,TAF2,GTF2E2,GTF2E1,CDK7,POLR2D,POLR2L,GTF2H5,GTF2H2,TAF7,TAF10,POLR2F,TAF9,GTF2A2,GTF2F2,POLR2G,GTF2B,TAF11,ERCC3,POLR2I,GTF2F1,GTF2A1,GTF2H4,POLR2C,CCNH |
| 5.626e-04 | -7.48 | RNA Polymerase II Transcription Initiation And Promoter Clearance | REACTOME pathways | R-HSA-76042 | 47 | 26 | 10285 | 3229 |
POLR2F,TAF7,TAF10,POLR2G,TAF9,GTF2A2,GTF2F2,GTF2H2,POLR2D,POLR2L,GTF2H5,GTF2E2,GTF2E1,CDK7,MNAT1,TAF2,POLR2B,GTF2A1,CCNH,POLR2C,GTF2H4,GTF2F1,POLR2I,GTF2B,TAF11,ERCC3 |
| 5.646e-04 | -7.48 | nucleocytoplasmic transport | biological process | GO:0006913 | 244 | 96 | 18204 | 5365 |
KPNA6,DRD1,RSRC1,NUP35,CITED1,STRADB,ABCE1,DDX39A,CSE1L,SPRN,PML,NUP62,CDKN1A,XPO5,NUP153,CASC3,NUP50,POLA2,CCHCR1,SEC13,ANP32A,NUP37,EIF4A3,NXT2,ING1,NFKBIA,ENY2,POLDIP3,MAGOH,CHP1,XPO1,CALR,RANBP6,THOC3,ZC3H11A,LMNA,SYK,FAM53B,PPP3CA,RANGRF,AKT1,CTDSPL2,FBXO22,PRKAG1,IPO8,XPOT,KPNA2,SMG5,CDAN1,TXNIP,DESI1,UBE2I,RBM15B,SFN,CAMK1,EGR2,RPL23,PPP1R10,ALYREF,RAN,PIK3R1,CDKN1B,SMURF1,FAM53C,TNPO3,GLE1,ALKBH5,FYTTD1,THOC1,EIF4E,TRAF3IP2,AHCYL1,NCBP2,PHAX,MAGOHB,DDX39B,THOC6,THOC2,STK4,TP53,HNRNPA1,NOP9,NUP107,KPNA1,PHB2,RPAIN,HIKESHI,HNRNPA2B1,NUP42,STK3,RPS15,SQSTM1,TNPO2,CHTOP,NXT1,HSPA8 |
| 5.670e-04 | -7.48 | regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000045 | 186 | 76 | 18204 | 5365 |
GPNMB,PSME1,MIR222,RGCC,ACVR1,MIR208A,SMARCD3,PLCB1,MIR214,CCNH,CDKN1B,MIR193A,CDK7,CYP1A1,BCL7C,CDC73,PSME2,DLG1,RPS27L,ECD,MIR519D,CCND1,LSM10,CTDSP1,MIR221,AIF1,PML,SMARCB1,RRM1,CDKN1A,MNAT1,MEPCE,CCL2,MIR638,FBXO7,MIR137,MIR29C,PTEN,MIR29A,EZH2,RB1,DCUN1D3,CDKN2D,PRMT2,TERT,ZNF655,CRADD,CACNB4,MIR16-1,AKT1,BCL7B,ACTL6A,MIR495,FAM107A,SMARCE1,CTDSP2,RPL26,JADE1,BTN2A2,KLF4,UBE2E2,CDK2AP2,TP53,ACTB,MIR133B,ACTL6B,CRLF3,MDM2,ADAMTS1,MIR15A,RPA2,TMEM14B,CCND3,CDKN2C,FGF10,FBXO31 |
| 5.683e-04 | -7.47 | T cell activation | biological process | GO:0042110 | 315 | 120 | 18204 | 5365 |
FKBP1A,CD151,IL2RA,RAB27A,LCP1,GPR89A,RAG1,FOSL2,CD1C,KIT,NDFIP1,CCL21,GJA1,MSN,RHOH,DLG1,CCL19,NHEJ1,EFNB1,IRF4,IL2,DPP4,PIK3R3,SMAD3,LMBR1L,CD2,IL2RG,CCND3,TOX,SELENOK,NCK1,RAB29,CTNNB1,GPAM,TESPA1,RABL3,BCL6,PTPN22,PPP3CA,CD1D,SYK,HMGB1,BATF,SLAMF9,STK11,RPL22,TNFSF18,PKNOX1,STAT6,CCR7,CCR6,IFNA13,WNT10B,RC3H2,EGR1,SOCS3,IL15,IFNB1,IL7,ITK,CD80,NCSTN,B2M,CD28,IL23A,KDELR1,FKBP1B,JAK1,ALKBH5,IL4,PRKCQ,PSMB11,SLA2,TNFAIP8L2,IRF1,PSMB10,IL20RB,PIK3R2,CD3G,IFNK,PIK3R1,PSEN1,CD247,CD4,IFNA2,PTGER4,PDP2,JAML,LIPA,IL12B,TP53,FCER1G,IDO1,ICAM1,STOML2,FOXP1,CD86,LEPR,IFNA10,IL6,IL21,AZI2,RSAD2,CLEC7A,TRAF3IP2,BAX,LILRB1,HSPD1,FOXP3,PRDX2,CD83,SASH3,NKAP,LEP,CDK6,TNFSF8,PELI1,PIK3CG,FGL2,MICB |
| 5.687e-04 | -7.47 | STX11 (syntaxin 11) | protein interactions | 8676 | 147 | 60 | 19454 | 5460 |
TADA3,NAPA,CCHCR1,EXOC5,PRPF31,SMARCE1,NTAQ1,MAGOHB,KCTD9,SNX3,NDFIP1,VAMP3,SCNM1,LRRC1,STX10,BORCS5,CDR2,MFAP1,NDE1,FAM161A,STXBP1,KDM1A,YKT6,GOSR1,CCDC184,PSMA3,STX1A,KXD1,ZCCHC10,NDC80,SHC3,SUV39H1,SPPL3,VTI1B,PPP1R18,SNAP25,EIF2B5,PRPF18,STX6,SLC38A2,HSBP1,CDR2L,VAMP2,DISC1,HGS,PSMC3,RNF8,TBK1,SNAP29,MAP1LC3B,CRYBA4,STX11,CDCA7L,VAMP8,STX8,EIF1AD,TCEA2,SIKE1,HAPSTR1,SNAP23 |
| 5.687e-04 | -7.47 | SELENBP1 (selenium binding protein 1) | protein interactions | 8991 | 147 | 60 | 19454 | 5460 |
SRFBP1,FNTB,CAPZA2,MMACHC,DXO,PIR,OTULIN,FSTL1,OAZ3,TFG,ZNF24,ST6GALNAC3,PMM2,ORMDL3,TRA2A,LYPLAL1,AGR2,NPSR1,TRMT5,TNFSF13,USP15,MT1X,SCG5,ARL11,GATD3,EED,SUMO2,CPLX3,TMED9,RAB11B,RAB39B,SRSF10,KDELR2,DRD3,ELMOD1,FKBP1A,MED31,LACC1,FOS,FLYWCH2,POLDIP2,FOXP2,CRYZ,FBXL4,NAA50,AR,GORASP2,FBXO7,SAMHD1,BLOC1S5,CSGALNACT1,CYRIB,CMBL,RAB9B,B3GALNT1,ANKH,F11R,GPX1,ESR2,LRIF1 |
| 5.689e-04 | -7.47 | FBXL17 (F-box and leucine rich repeat protein 17) | protein interactions | 64839 | 84 | 38 | 19454 | 5460 |
SCPEP1,KLHL28,DVL2,PPM1G,SKP1,SLC31A1,BACH1,ETFA,HADH,TMEM126A,KLHL3,SUFU,NOTCH2,TMOD1,KLHL12,ZBTB42,ENC1,UAP1,ZMYM2,ZBTB18,CSNK2B,KLHL7,METAP2,SCG5,ZBTB33,PXYLP1,SRC,VIRMA,KBTBD6,HNRNPL,OLR1,PCCB,IDO1,KLHL9,CLPX,CUL3,DCAF11,PHF7 |
| 5.693e-04 | -7.47 | CDKN2B (cyclin dependent kinase inhibitor 2B) | protein interactions | 1030 | 73 | 34 | 19454 | 5460 |
CDKN2D,MYC,AKT1,STK11,EPHA2,BECN1,AK2,NIF3L1,CDK6,MAP2K6,CCDC90B,TRAF1,GRM1,FZR1,CDK17,ZBTB17,SPG21,KDELR2,MAP2K3,CDK4,TP53,RAF1,MET,ARPC3,CDK8,TERT,IGF1R,EP300,PICK1,CDKN2C,CNKSR3,RNF20,TGFB1I1,NF2 |
| 5.694e-04 | -7.47 | response to peptide hormone | biological process | GO:0043434 | 381 | 142 | 18204 | 5365 |
SHOC2,CCNA2,EIF2B5,HADH,EGR2,OPRK1,SP1,IDE,PPARG,SESN2,JAK1,GAB1,BTG2,PIK3R1,PCK2,PLCB1,PIK3R2,CDO1,CDKN1B,GNRHR2,TIMP1,EIF2B2,SRSF4,EGR1,ALPL,TRIM44,EDNRA,NR4A2,CAV1,PAX6,NFE2L2,REG1B,UPRT,PPARA,LEP,INSIG2,ZBED3,SRC,GHR,DAG1,PTPN1,CA2,INPP5K,ERRFI1,MGARP,TSHR,AKT2,COMT,CSH1,BGLAP,MIR107,SOCS2,MIR143,MIR379,ROCK1,CREB1,GPR173,AHCYL1,CSK,IGF1R,SOS2,HADHA,SLC2A8,F7,ACVR1C,YWHAG,MDM2,TNFSF10,PIK3CA,TRIM24,RAB13,STAT5A,NCOA5,FOXC2,RARRES2,TLR2,CYP1B1,STAT2,XBP1,NEFL,CD2AP,CPEB1,GRIA1,REG1A,CYP11B1,SLC22A12,TWIST2,CRHR1,CITED1,RB1,RAB31,KCNJ8,SHC1,GSK3A,HDAC5,NFKB1,CRY1,STAT1,CYC1,LRP6,CAV2,PCSK9,VAMP2,INPPL1,EIF4EBP2,FOS,JAK2,HRAS,STK11,GRB10,SELENOS,FBP1,STAT6,AKT1,TBC1D4,CXCL12,KBTBD2,GCLC,COL3A1,GPT,EIF2B3,RETN,OXTR,GJB2,CRHBP,GH1,SESN3,AANAT,CTSK,MIR145,AGTRAP,MAP1B,NPR2,RAF1,SMAD3,PIK3R3,ROCK2,IL10,CYP11B2,UCP2,SLC2A1,ADIPOQ |
| 5.706e-04 | -7.47 | negative regulation of phosphorus metabolic process | biological process | GO:0010563 | 378 | 141 | 18204 | 5365 |
PID1,CBL,CAMK2N2,GADD45A,RGN,YWHAB,MIR20A,GSKIP,CRKL,TRIB1,SLC8A1,TRIM63,PAK2,FIS1,IL2,CTDSP1,CDKN1A,MACROH2A1,LRP6,PKIB,FKBP1A,DUSP6,PTEN,TSG101,RB1,ADNP,DEFB114,GSK3A,PPP1R8,CDK5RAP3,TESK1,HEXIM2,RGS2,IL1B,AKT1,DKK1,PTPN22,DNAJC10,CORO1C,STAP1,STK38,GRB10,DUSP10,PKIA,PYCARD,C9orf72,DDIT4,PRR5L,FBP1,ROCK2,DUSP22,MIR675,DUSP3,CHP1,MIR24-1,ADIPOQ,TNF,SPRED1,DBNDD1,CAMK2N1,DUSP1,NCK1,PPP1R1B,SPRED2,BAK1,GSTP1,HYAL2,CDKN2C,PGR,MIR711,PPP2R5A,CNKSR3,CDKN1B,SOCS5,IMPACT,TSPO,PKIG,MIR146A,PSEN1,PAQR3,DNAJC3,LILRB4,ARPP19,INHA,PPARG,IGFBP3,SFN,MIR212,NTRK3,MIR218-1,IKBKB,SOCS3,PAX6,MIR137,CAV1,LGALS3,UBASH3B,CAV3,NF2,CEP85,SWAP70,CDKN2D,FKBP1B,ERRFI1,ANGPT1,INPP5K,PTPN1,MIR132,PTPRQ,PARD6A,TRIM27,PPARA,THY1,CTDSP2,SPRY1,HEXIM1,SOCS4,ZBED3,PRNP,TP53,IFNG,FKBP8,TAF7,YWHAG,DYNLL1,MIR106B,HSPB1,NUPR1,PRDX3,DUSP19,MIR15A,PPIA,GNAQ,MIR34A,RTRAF,IER3,SFRP1,FLCN,PDCD4,ROCK1,BAX |
| 5.706e-04 | -7.47 | positive regulation of monoatomic ion transport | biological process | GO:0043270 | 212 | 85 | 18204 | 5365 |
MIR210,MCHR1,UCN,CCR1,NDUFA4,KCNIP2,DRD1,PLP1,FGF13,SRI,LGALS3,PPP3R2,NPSR1,CHRM1,COX17,NHERF1,CXCL10,SLC6A4,CAV1,CCL2,SPHK2,TMSB4X,ACTN4,EDNRA,OPRK1,LILRA2,STIM1,F2,CCR2,ATP1B1,MIR21,DLG1,CFTR,NOS1AP,TSPO,MLLT6,CNKSR3,G6PD,CNTN1,AMIGO1,GSTO1,ATP1B3,P2RY12,BAX,SCN1B,BAK1,AHCYL1,MIR1-1,VMP1,CXCL11,KCNMB1,IL13,LACRT,KCNC1,CASK,STC1,CXCL9,CACNB2,CCL5,CHP1,CX3CL1,ABCB1,CACNB3,SCN3B,HCRT,PRSS8,XCL1,IFNG,HOMER1,TESC,THY1,APLNR,FGF12,ADRB2,LEP,KCNJ2,P2RY1,CCL3,PPP3CA,AKT1,CXCL12,GSTM2,STAC3,ADORA1,TRPC1 |
| 5.708e-04 | -7.47 | GPRC5B (G protein-coupled receptor class C group 5 member B) | protein interactions | 51704 | 98 | 43 | 19454 | 5460 |
ADGRE2,STX6,STX5,TSG101,CD63,ITGA6,PREB,HS2ST1,FLOT1,ACVR1B,KRAS,JAK1,DLG1,TMED1,GPAA1,CSGALNACT1,NAPA,SCFD1,CD226,CSGALNACT2,PKP4,EPS8,CSK,MLF1,SEC63,MYRF,YES1,ATP5F1B,STX10,ODR4,STUM,SCAMP2,VAMP3,SIGMAR1,HSP90B1,SDCBP,STXBP1,GOSR2,LPAR1,ADRB2,CMTM6,MIA2,LRP10 |
| 5.708e-04 | -7.47 | TM9SF4 (transmembrane 9 superfamily member 4) | protein interactions | 9777 | 98 | 43 | 19454 | 5460 |
FAM174A,ICAM2,GPBAR1,ATP1B3,H1-10,H2AZ2,KLK5,S1PR4,S100A6,SLC1A1,SPPL3,HNRNPL,APLNR,ATP5PD,CLRN2,B4GAT1,SLC25A12,H1-5,FAM162A,TP53,FCF1,RPA2,DRD3,GP9,STX12,TSPAN3,CXCR4,TMX2,RAB1A,RPA3,TMEM106B,TSPAN15,VIPR1,HSPA8,RPAP3,EMP3,SPCS2,LPAR1,CDCA7L,STX7,ZC3H15,TSPAN11,SACM1L |
| 5.708e-04 | -7.47 | DACH1 (dachshund family transcription factor 1) | protein interactions | 1602 | 98 | 43 | 19454 | 5460 |
AHCYL1,PAX6,FGF12,EWSR1,CBX3,SMAD1,SOX2,JUN,TP53,RPL35A,DCK,SMAD3,SIN3A,BRD3,SMAD4,CD81,ZCCHC10,FOXC2,RNF14,COIL,EYA3,HDAC3,NF2,SOX3,TERT,NUP50,PPM1G,HBB,WDR83,APEX1,UBE2I,SYT2,EIF4A3,ELK3,CREB1,TRIM44,CPSF1,PPIG,STK11,NCKIPSD,MYC,CREBBP,HNF1B |
| 5.708e-04 | -7.47 | MTFMT (mitochondrial methionyl-tRNA formyltransferase) | protein interactions | 123263 | 98 | 43 | 19454 | 5460 |
MRPS17,MRPL22,KGD4,MRPS33,MRPS11,MRPS18B,MRPL49,NDUFS6,NDUFS3,PDHA1,BCS1L,ETFB,PRSS35,NDUFA2,RAF1,MRPS23,MRPL24,NDUFS8,MRPL50,GATD3,MRPS9,MRPS26,NDUFV2,MRPS35,GRSF1,MRPL20,MRPS7,FBXW7,NDUFS2,NME4,TRUB1,TWNK,NDUFA5,MRPS34,MRPL12,MRPS28,DLST,TACO1,STK11,MRPS25,MRPS16,PYCR2,PYCR1 |
| 5.708e-04 | -7.47 | AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase) | protein interactions | 178 | 98 | 43 | 19454 | 5460 |
GLO1,COPS5,CUL3,CUL2,MOV10,AHSA1,FKBP1B,BRCA1,RAN,FBXO32,CCNF,SDHB,USP5,VIRMA,APEX1,PSMB6,CDK9,PRNP,DCUN1D1,TOM1L2,LGR4,GCLC,YTHDF2,RAF1,STBD1,PRKAB1,FKBP1A,RNF126,PIH1D1,HEXIM1,UBE2M,PRKAG1,RPA2,ADSS2,EMC2,HSPA8,CDK5,RPA3,BAP1,ASB3,MEPCE,PYGB,EMC1 |
| 5.708e-04 | -7.47 | PLEKHG3 (pleckstrin homology and RhoGEF domain containing G3) | protein interactions | 26030 | 98 | 43 | 19454 | 5460 |
RAC2,SPIN3,ZMYM2,NXT1,CTTN,ACTA2,SURF6,ESR2,VIRMA,ACTB,RHOJ,HNRNPL,RPS29,YWHAG,YWHAH,SFN,MYC,AKT3,VMP1,YWHAB,TMOD2,YWHAZ,SNRNP70,RHOB,CIRBP,RHOG,TMEM147,SLC39A3,TMEM263,S100B,IL13,HSPA5,CHMP2B,KDM1A,CHCHD2,DET1,CDC42,PPP1CB,SOX2,ATG16L1,CAPZA2,LMNA,CSNK1A1L |
| 5.759e-04 | -7.46 | SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2) | protein interactions | 6455 | 150 | 61 | 19454 | 5460 |
GTF2F2,GANAB,RAB11A,MYC,CREBBP,POLR1B,DNAJB6,CALU,NTRK3,RHOB,BICD2,YWHAZ,NIF3L1,LAMTOR1,TTC1,ARPC2,HSPA8,PML,RPA3,BAP1,STAU1,NF2,SGF29,ARHGAP1,LAP3,ANGPTL2,CSNK1A1,SH3GLB2,STX17,FGFR1,RPA2,PSMB1,FBXO32,HRAS,ZBTB2,CGAS,RPL35A,GTF2E1,YWHAH,YWHAG,PFDN5,EEIG1,CALR,POU5F1,CRTAP,SCAMP5,THG1L,EWSR1,TRIP4,ANP32B,RAD21,RIGI,PFDN1,HNRNPK,SPG21,TULP3,E2F4,CCR1,SH3GLB1,ACTR2,GPX7 |
| 5.759e-04 | -7.46 | NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1) | protein interactions | 4706 | 150 | 61 | 19454 | 5460 |
MRPL23,KCTD9,ACTB,CLIC4,DDAH2,TACO1,CCDC90B,ENO1,PPP1R16A,GLOD4,RIT1,MYC,AUH,FMC1,ACO2,LMO2,ATP5F1A,NTAQ1,OIP5,NT5C3A,ATPAF2,SOD1,TXNL1,GFM1,PRDX6,RBM18,IDH2,FEM1A,GSTP1,MTRES1,ARCN1,DDAH1,SMYD3,LYRM2,MALSU1,SDHB,SSBP1,HDHD3,GATD3,NDUFA1,GRSF1,ETFRF1,DNAJC30,ETFA,PSMB10,SDHAF1,HINT2,FHL3,NDUFS6,NDUFS3,VAC14,PSMC3,HINFP,FEN1,CMPK1,MRPL11,ETFB,PGM1,POP5,METTL15,THAP1 |
| 5.802e-04 | -7.45 | heterotrimeric G-protein complex | cellular component | GO:0005834 | 33 | 19 | 19108 | 5553 |
GNB3,GNB1,GNAZ,GNAI3,GNG10,GNAI2,GNA14,GNG2,GNG13,GNG12,GNA11,GNG3,GNG7,GNG5,GNAO1,GNGT2,GNG11,GNB4,GNAQ |
| 5.818e-04 | -7.45 | Signaling by SCF-KIT | REACTOME pathways | R-HSA-1433557 | 337 | 134 | 10285 | 3229 |
TP53,PSMC3,CD86,PSMA1,IL3,RPS27A,SPRED1,PHB1,PSMD4,SHC1,RASGRP3,PSMB4,SEM1,DUSP1,GAB1,HRAS,LAMTOR2,PPP2CB,KIT,IL5,PIP4K2C,PSMB2,PSMD1,AKT3,AKT1,PEA15,PSMA6,PIK3CA,FGF16,IL2RB,LAMTOR3,CAMK2G,VWF,CUL3,PSMC1,IER3,RAP1B,MAP2K1,KRAS,UBA52,FGF22,WDR83,RAF1,TNRC6C,PSMD10,FRS3,SRC,DUSP9,MOV10,MMP9,FGF10,PIK3AP1,MET,PAQR3,FGF23,PSMA5,PTEN,SPTAN1,PPP2R5E,PIP5K1A,PSMB3,PEBP1,YES1,PIK3R2,IL2RG,ICOS,MDM2,YWHAB,GRB10,DUSP6,PPP2R5A,FGF1,GSK3A,BAD,MAP3K11,GRAP2,NEFL,DUSP10,FGF3,PSME2,PSMD6,HBEGF,PSMB9,SPRED2,IL2RA,AKT2,SHC3,RAP1A,STAT1,PIK3R3,CDKN1A,CSF2,FGF7,JAK1,PSMD12,PSMD14,GRAP,PTPN11,PRKCA,UBB,PPP2R1A,CBL,STAT5A,SPTBN1,CMA1,PPP5C,AGO1,ANGPT1,PSME1,PSMD7,CD80,FGF17,PSMA4,PSMC5,FGFR1,IL2,PSMB11,PSMB10,PSMA2,PSMB6,CD28,DLG4,BRAP,CSK,CREB1,PSMD3,PSMB7,JAK2,PIK3R1,PSMB1,PSMA3,PSMB5,CDKN1B,PSMC4 |
| 5.823e-04 | -7.45 | RSBN1 (round spermatid basic protein 1) | protein interactions | 54665 | 153 | 62 | 19454 | 5460 |
ZBTB38,H1-1,CDC16,RPL7A,APEX1,RPL19,VIRMA,SNRNP40,RPL13A,RPL35,DYNLL1,RBMX2,PRKRA,FGFBP1,RPS3,PSPC1,RPLP0,RPL26L1,MACROH2A2,FGF13,H1-5,GNB4,COIL,CXXC1,RPL4,RNF113A,EP300,RSBN1L,RPS2,DRG1,BRD3,RPL10A,DDX23,DDRGK1,ZCCHC10,SURF6,RPS10,RPS16,LYAR,SRP14,RPL8,SRSF1,KRR1,PHB1,ZRANB2,CBX3,NFKBIL1,RBM34,RPL15,RAF1,RPSA,TP53,RPL28,RPL17,H1-6,KRAS,H3C1,HMGN4,RPL23A,RPL3,BCL7B,RPL31 |
| 5.823e-04 | -7.45 | TRIB3 (tribbles pseudokinase 3) | protein interactions | 57761 | 153 | 62 | 19454 | 5460 |
SNRK,PML,PPP1R26,DDIT3,PSMA3,SQSTM1,OIP5,EEF1G,UTP23,BCL6,MAPKAPK5,FAM161A,TIMM13,APOBEC3A,DET1,LMO3,APOBEC3C,PPARG,TCF19,PRKCA,ACACA,SCNM1,CSNK2B,PRMT5,ACTB,SIAH1,SMURF1,AKT1,LMO2,TNFAIP3,MYC,ATF4,SUB1,FBXO7,BAG3,AR,TTC23,PRR19,COP1,ARMC7,AKT2,CCT8,HNRNPF,TRIM63,RIGI,TOP3B,RPSA,CCT5,PPARA,SPG21,TIMM8A,BMPR2,TIMM8B,SMAD3,TCP1,EPHB6,UBTD2,CCT7,MDFI,CTNNB1,TRAF6,AKAP8L |
| 5.827e-04 | -7.45 | SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1) | protein interactions | 6602 | 330 | 120 | 19454 | 5460 |
BRD9,FBXO32,POLR2L,FEZ1,PPIA,PGR,ZNF511,SMUG1,BCL7C,YWHAG,ACTL6B,PRDX1,WWP2,ZCCHC10,NAB2,MED4,HSPB1,LHX2,PICK1,FAM168A,BCL7B,TOP2B,PAX6,ANP32B,KRAS,CHN2,JUN,SOX2,SAP30,RAF1,CSNK1E,SMARCB1,EIF1AX,FAM136A,POLR2D,MOB3C,SCHIP1,EZH2,NME1,SCNM1,RORB,ESR2,LDB2,ACTB,SMARCE1,THAP7,IRF1,RPS29,CCDC85B,MYC,HNF1B,HNRNPC,PRMT6,BLOC1S5,GCC1,BEX3,ARRDC3,NUP50,DDIT3,SMARCD3,ACTMAP,FOS,GINS3,CDSN,PACSIN3,ACTL6A,DUSP14,BEND5,ELF5,PIH1D1,PPARG,LDLR,KMT5B,CDC5L,KLF1,E4F1,SUV39H1,IRF4,KPNA1,BRD3,ANKRD49,SNIP1,MDC1,RIGI,KPNA2,CRYBA4,ING1,ESS2,H2AX,SOX9,TP53,DISC1,FGFBP1,TRIM27,ZMAT5,ZNF655,VIRMA,TRIM54,RUNX1,GPRASP3,FBXO7,PCBD1,AR,NONO,SERTAD3,COL1A2,EGFL7,SQSTM1,RPA3,LDOC1,SS18,HDAC3,KDM1A,HMGB1,CFTR,FAM161A,CDR2,PAX9,RPA2,P3H1 |
| 5.834e-04 | -7.45 | MRPS17 (mitochondrial ribosomal protein S17) | protein interactions | 51373 | 225 | 86 | 19454 | 5460 |
HSPD1,RPL31,PREPL,MRPS11,HINT2,PDHA1,TULP3,HNRNPL,RMND1,GATD3,RHOG,MRPS26,MED4,MRPS35,MTRF1,DDRGK1,MRPL9,UFL1,HSCB,MRPS7,RCCD1,EXD2,NGRN,RPL19,ESR2,DLST,CCDC90B,TACO1,FTSJ3,MRPS25,NOA1,MCAT,PMPCA,MTG2,MYC,AUH,MRPS33,VPS16,MEPCE,MRPS18C,FASTKD5,RPL3,MRPS18B,GFM2,MRPL11,STRBP,METTL15,AURKAIP1,APOBEC3D,CGAS,THOC1,FZR1,ZBTB2,MRPS23,RBM42,MGME1,MRPS9,SSBP1,TMEM70,CHCHD1,SNRNP70,GRSF1,NPM3,CRYZ,RPA3,RNF113A,GFM1,GRM2,MRPS34,ZNF770,KLF4,MTRES1,HEXIM1,TFB1M,ZNF574,CPSF4,RBMS2,KLF12,MRPS21,OPTN,MRPS28,RC3H2,MRPS16,DNAJC19,UBE2H,TUFM |
| 5.841e-04 | -7.45 | negative regulation of cardiac muscle hypertrophy | biological process | GO:0010614 | 35 | 20 | 18204 | 5365 |
PI16,RGS2,MIR25,G6PD,SMAD3,MIR214,ATP2B4,LMNA,FOXP1,TNFRSF1B,SMAD4,CAV3,PPARA,MIR21,TRIM63,PPARG,MIR145,GSK3A,MIR1-1,TOMM70 |
| 5.874e-04 | -7.44 | MAST1 (microtubule associated serine/threonine kinase 1) | protein interactions | 22983 | 222 | 85 | 19454 | 5460 |
MRPL16,RPS17,CSK,EXOSC1,HSP90AA1,HOXC4,UBE2H,MCAT,SNTA1,MRPS16,MRPS25,NOA1,YWHAZ,CHTOP,MRPS28,PRMT5,CSNK2B,PRKRA,LRRC1,PTEN,STUB1,PNMA1,PRDX2,MRPL23,MRPS21,RPL7L1,GTF3C4,MRPL12,GIT2,WTAP,MRPS34,USP39,HADHA,RFC4,ARHGEF6,PSEN2,FBXW4,MRPS7,HSPA5,MRPL17,RPS15,MRPL41,YWHAH,HNRNPA1,CSNK2A1,CTNNB1,ELOC,MOV10,ACOT8,RAB3D,MRPS35,STAMBPL1,MRPS26,RAB3A,YWHAB,TIAM1,MRPS9,MRTO4,PPP2CB,KRR1,TRMT61A,HSP90AB1,MRPL24,CDC5L,MRPS23,HNRNPL,PPP2R1A,STRBP,TRMT1L,MRPL47,MRPL11,GEMIN7,MRPL49,CYP2C8,PNMA2,MRPS18B,CDK5,MRPS11,CYP2C9,PPAN,MRPS18C,MRPS17,RIGI,AHCYL1,MRPS33 |
| 5.881e-04 | -7.44 | RBM22 (RNA binding motif protein 22) | protein interactions | 55696 | 156 | 63 | 19454 | 5460 |
SRSF7,ARGLU1,PQBP1,SNIP1,SNRPG,SSRP1,KRAS,G3BP1,CTNNBL1,TSSC4,EXOSC8,CD2BP2,ESS2,SNRPE,HDAC11,HOMER3,NUP35,CDC5L,RBM42,SNRPA1,THOC1,TOP1,PRNP,HNRNPA1,GTF2E1,PRPF19,MAGOH,KIAA1143,SF3B1,NKAPD1,PML,SNRPA,DDX39B,RPA3,AATF,YTHDF1,STAU1,RALYL,PRMT2,RBFOX2,TXNL4A,SF3A1,TFIP11,LSM2,CTBP1,LMNA,RPA2,EIF4A3,SNRPB2,ESR2,SNRNP40,SNRPB,BTF3,HNRNPC,CUL3,MYC,RIT1,UBE2H,ELAVL2,NCKIPSD,NOA1,BICD2,SPOP |
| 5.894e-04 | -7.44 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-B_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-B_cell_lymphoma_unspecified | 24 | 15 | 16828 | 4835 |
IDH1,SRC,SF3B1,IDH2,NOTCH2,CDKN2C,JAK2,TP53,EZH2,MYD88,TPM3,PTEN,CDH11,PIK3CA,CD79B |
| 5.901e-04 | -7.44 | cellular component organization | biological process | GO:0016043 | 5636 | 1754 | 18204 | 5365 |
KCTD3,FBXW7,ZDHHC17,HSCB,NOG,APOBEC3C,STX11,OMG,NLRP1,NUF2,RAB14,TRMT112,TRIM32,TMOD3,MED9,YKT6,RAB33A,MED23,FA2H,RHOBTB1,RAB33B,NAIF1,RS1,UBAP1,APEH,DPP4,PIAS1,TRMT10B,VPS54,VAMP3,XRCC5,CYRIB,ACOT13,FEZ1,APOBEC3A,DMPK,STX6,CLRN2,RAB5A,H2AC1,TACO1,PRPF31,CENPP,USE1,SLC12A2,TBCEL,LRRC61,SPMIP6,TIMM8B,CCDC42,GFOD2,IGF2BP1,NPPC,CLXN,CHCHD2,GLRX5,CCL2,GCFC2,EIF5B,ARL6,TUBB,TRAM1L1,DCTN6,CBLN4,HIKESHI,BACE1,STX18,THY1,PMP2,TRAPPC2L,TFEB,COX14,HSD17B8,PARP11,H1-3,RB1CC1,CHTOP,NDUFAF6,P2RY12,GFM2,STX10,ROCK1,SUPT4H1,CDSN,CACNB2,ARFGAP3,TAF10,PIK3CA,ZC4H2,SPTAN1,COX20,RAB22A,NTF4,APEX1,NLGN1,DEK,NDUFAF4,STMN2,NDUFB8,BICD2,WDR19,PIK3R2,AGK,TERB2,BSCL2,YWHAZ,PRKACB,AMIGO1,MTA2,VRK1,VEGFA,BORCS7,PPM1K,SAMHD1,METTL21A,GTF3C4,SATB1,TMEM170A,NSMCE3,EIF3E,MTPN,PRELID1,RRM1,NYAP2,TMED4,FKRP,GPC1,SLC25A31,ITGA2,WNT7A,NPY,BMP1,AIFM1,TGFB3,SIAH2,BAK1,MAP1B,B4GAT1,CIBAR1,BRD9,SNX18,PYROXD2,SIRT7,HIRA,PPFIBP1,PAK2,LHFPL4,AR,SOD1,CNR1,KIF2A,REEP4,NUBP2,MND1,TERC,TUBB4B,PID1,PRKCE,KRT8,RGMA,PARL,ATF1,LCP1,PIP5K1A,TAF11,PHC1,B4GALT1,GNB3,NRP1,RPGRIP1L,SNTA1,HAX1,SPRY1,SNAP29,E2F4,LMNB1,CLIP3,TENT4A,SMARCE1,PPP1R12A,PPP2CB,ACTL6A,FOXP3,AKT3,TP53INP1,SDC2,AHCYL1,HAPLN2,BAHD1,CETN2,ASPM,PADI2,CHMP1A,DDX39B,MIEF1,IMMP2L,MACIR,BORCS6,BBS5,LRRTM1,GLTP,UBE2K,MCM6,MMP14,NACC2,DNAJB6,SYT4,SFN,SEMA4C,AQP11,EHD4,TNIK,UBE2S,AJM1,MMP20,SMARCD3,ATG7,HDAC3,FHOD3,CATSPERZ,OPTN,BABAM1,CDC42EP4,OTUD6B,CHMP2B,TP53INP2,TPPP2,SMYD3,PAX6,SAR1B,PEX5L,SIPA1L1,CRYZ,KDM2A,PITPNA,PCLAF,MYO1B,CHRDL1,GTF2A2,SEC22A,FGF7,RANGRF,CLDN4,CXCL12,GOLPH3L,KCNMA1,CDK5,TEX12,TESPA1,MID1IP1,RPA2,PHB1,CLVS1,HAUS2,VAPB,NGRN,GINS4,CX3CL1,PPT1,MUL1,NDUFAF2,ARF6,CLDN3,H1-5,IRF4,CSNK2B,RP2,PPM1D,MIR214,H2AB1,COA4,NLRP3,EXOC3,TPPP3,BOLA3,KCTD9,TMEM107,ILK,RPL6,EID2,CASP4,BOLA1,TAFAZZIN,TRAPPC6A,ZNF365,TNFAIP1,SH3GLB2,CD2BP2,WDR44,SDHAF1,NUP35,SUPT5H,TOMM20,TOP1,LSM14A,MED4,LSM3,RBMX2,JADE1,USP39,DLG4,IFI6,TRAM1,ZNHIT3,TMEM33,RAB30,PTPN1,HSPA8,CYRIA,KIF3B,OCEL1,GABRA1,SDCBP,LYZL4,MDM2,STARD5,MAP1S,TP53,RBM15B,UFL1,RETREG1,CHMP4C,CD247,DAAM1,CAP2,BET1,S100A6,TLCD2,DDX46,FOXJ3,PIWIL1,ST7,LRFN3,CFAP91,HEXB,DET1,SNX2,CDC123,GABRA2,CDAN1,GPM6A,CEP70,SDHAF4,SF3A1,SEMA5A,CCR7,MAT2A,RNF8,PRSS1,REEP6,C9orf72,CFAP20,MCM8,MBD3,ZNHIT6,DDX4,ELMO2,ADRB2,RFC2,GAS8,RAB3B,CHRAC1,TOMM22,DKK1,H2BW1,KXD1,RAB1B,VAMP8,PKP4,NAPG,RFLNA,ADD1,GJB2,RERE,LTO1,LSM2,EMC4,JAGN1,LORICRIN,SYNGR2,LRWD1,GRXCR1,PPFIA2,SNAI2,NAPA,LRRC8C,EFNB1,MTRF1,EMC1,IFRD1,RAB3A,VTA1,GHRL,ERO1A,BAG3,SART3,SOX9,SYNGR1,NUCKS1,SKA3,VIPAS39,SLC66A2,FKBP1A,CYTH2,TAGLN2,PRPF19,PELO,ING5,HEY2,C1QL2,SETD7,ZNF518B,STK3,PARD6A,CFL1,NDUFS8,MIF,SHPRH,BCL10,FLCN,GGCT,NUPR1,CRYAB,AGO1,FAM50B,SPEF1,CST3,FCHSD2,KCNB1,RPS14,DDX42,FXN,CBLN2,MATN4,IFT22,MDC1,NTMT1,NDUFC2,SWAP70,CMA1,GPR35,COG1,RUVBL2,AP2M1,ING2,EFNA5,CPTP,TMEM11,FCHO2,NDUFA5,FCGR2B,CCDC32,KCNG3,SETD5,UBL4A,PCGF3,COL1A2,TAF9,ESAM,TEX19,PLSCR4,TMEM108,RILPL2,KMT5B,IFIT2,CDH7,ATG16L1,HMGN4,SMAD3,ISCU,GPAA1,LRTM2,TXNL4A,NRN1,RAB19,RNF40,ARMC1,SYCE3,ESYT1,NLGN2,TRAF6,HP1BP3,B3GNT2,TESK1,KCNJ8,LRIF1,IZUMO1,KCTD16,PLP1,MRAS,EFHD1,PSPC1,SYBU,ISCA2,PSEN2,TRIM21,SF3B6,EXT1,PTGES3,MTMR2,NRDE2,SRGN,SRC,SLC25A46,ANGPT1,PPID,PDCL,MEF2A,PRKRA,TOM1,USP30,CAMSAP2,BIRC5,GPR37,STX5,MEIOB,FLRT2,IFI16,ZMYM6,AP3S2,STARD4,TFIP11,BLOC1S5,ACTR2,TMED3,NBN,SNCG,SNX1,CORO6,PQBP1,MKLN1,RND3,BMPR2,TOMM6,MIR29A,BNIP3L,EDC3,CELF6,MAIP1,NDC80,MECP2,SIGMAR1,EMC9,PRMT5,GABARAP,H2AC6,RSPH1,PDLIM3,SDHAF2,LMNA,ZMYND11,GMNN,MIOS,STARD13,CRTAP,SLC1A2,CTSK,NPR2,CCL24,IFT25,GPX1,EP300,GEMIN8,AP1M1,RFC3,CAVIN2,VDAC2,UQCC3,WDR77,CATIP,VAMP1,HSD17B10,BOK,PHF21A,TOR1AIP2,SKP1,RIC3,CRKL,ATG4C,MSN,TMEM126B,ENKD1,IZUMO1R,H2AC4,TIMM8A,FAM91A1,GSK3A,EIF3G,BAD,SSX2IP,B4GALT7,ATP8A1,BCL2L1,STXBP1,LIMS2,WSB1,MTA3,PALS2,GNMT,LUC7L3,FLOT1,SERPINA5,KCNA2,MORC2,VPS33A,CHCHD6,MRPS7,HSPD1,CBX3,ROPN1B,COPS7A,CFL2,PCDH17,RTKN,CAMLG,UBB,MYO6,KCNF1,STOML2,SNRPB2,RNF14,AQP4,CD9,NOPCHAP1,FMC1,SEPTIN6,B9D2,ILDR1,RTN4,MYBL2,EXOC1,TIA1,MFN1,LST1,SNAPIN,RCBTB1,RPLP0,H3C1,RMI2,CHMP2A,CLDN11,SIN3A,AQP2,BCL2A1,VAV2,S100A10,PREB,ZNF304,BRIX1,STXBP6,AGER,PLEKHF1,TAPT1,RHOB,KATNAL1,YTHDF1,CORO1C,INO80C,STX1A,TRAF2,CBX5,H1-1,ETF1,CNTNAP1,ATL1,RPS3,TRIM6,TMEM106B,SNX14,PLAAT3,H2AZ1,ROCK2,INA,EXOC5,CGGBP1,BOLA2B,EXOC8,GAS2,UFM1,RPS28,DES,ACOT8,RHOH,MTRES1,DDR1,STK38L,LDB1,FBXW11,RAG1,PSMG3,H2AX,PLEKHJ1,LGI1,OGG1,PSMD10,PLEKHA8,CFDP1,RPF2,PPAN,SPHK2,ATG3,CIDEB,BORCS8,CEP97,CCL11,C1QL1,POLR1B,PTPN11,HDAC11,HUWE1,UGDH,GHITM,DNAAF10,TFPT,FKBP10,LRRC8A,TRIM27,ATXN1L,FGFR1,NDUFAB1,EMP3,PIWIL4,EEF1AKMT3,VPS72,MITF,VPS4A,SRPRB,BLOC1S2,TAF7,LIPA,RACGAP1,CSNK1A1,FUNDC2,YIPF4,RAB39B,TPM3,RPL23,TSPO,BTG2,RAP2A,RNF20,TMOD1,STX12,JUP,CETN3,RHOJ,CAPG,CEP41,H2BC14,RPS5,MREG,EZH1,RAB32,CHRNB2,OSBPL8,RAD21,CNTN2,CLN8,TPBG,MYRF,GAPDH,CNOT7,VPS4B,FARSA,TIMM10,CDH13,PIWIL2,FOLR2,SNX33,TPPP,WDCP,FUNDC1,GREM1,RAP2B,NDUFA1,TRIM37,SOX2,EIF3J,C1QC,NPM3,PEX13,SEC22B,RING1,PCNA,SHOC1,EMC2,PLSCR3,NOTCH2,REEP3,SRPK2,SNRPD3,KLHL12,SMC4,CHP1,TGFB2,PAK6,ATP1B1,NDUFA2,CHCHD3,GPX4,NFE2,TADA3,CIRBP,CCL21,CFAP298,FZD3,CTNNA1,TNR,SPECC1L,BAZ1B,SHC1,CHGA,NAP1L5,PRKCB,SNRPA1,RAP1B,SNRPE,HPS6,NCKAP1,MAD2L1,TMOD2,MACROH2A1,PLS3,EIF2S2,NDUFA12,HSP90AA1,USP15,UQCC6,WDR45,CDK5R1,KDM4B,H2AC13,SNAP25,PSRC1,TRIM36,GATAD1,CLDN6,INPP5K,SNCB,TOMM40,SELENOF,CREB1,TUBA1B,TMSB10,IER3,SLU7,ZFAND6,TDRD7,PRDX3,ZNF207,PEG10,ATP6V0B,G3BP1,ATG9A,RPS27L,ARB2A,EGR2,IFIH1,CLVS2,ZMPSTE24,NUDT5,IFT57,TAF2,SNX3,PTPRZ1,HSP90AB1,KCTD17,MSRB1,CNTROB,LCA5L,CAV3,CFAP161,ACHE,STARD3NL,PFDN6,ATP6V1A,ARPC2,VCPKMT,USP8,FOXA3,POLDIP2,SGF29,HDAC6,ALKBH4,TMED9,STK11,CCAR2,MED22,STX16,GK2,MED10,ARFGEF1,CD40,ASIC1,VMP1,HR,NPC2,TIMM13,MRM2,STAR,SPTBN1,CD2,SLC2A1,KCTD10,PARP2,WEE2,YIPF5,NTN4,FAM161A,PICK1,AKAP8L,RNF26,NPTX1,PPIF,CDC42EP3,SNAP23,TLR2,CYP1B1,FKBP4,GLRB,ATP5F1D,PIH1D1,DRD1,CACNB4,TMEM231,NHERF1,CLCN6,SYP,H2AC25,NUP62,EHD3,EXOC2,WBP2,HNRNPA2B1,NECTIN2,PMP22,FASLG,NEGR1,NDE1,NDUFB10,H2BC17,UQCC2,POMP,WRAP53,CENPW,STAU1,NEO1,LYPLA2,SURF4,ADRM1,CAMP,GNPAT,ETV6,MIR143,TCAP,PAFAH1B1,IFT52,NLE1,RCCD1,TIAM1,NDUFAF3,NDUFS2,CDC23,BMERB1,TNNT2,NUP107,FIG4,CBX7,TIMM21,TCP1,H2AJ,COX16,STX17,NIBAN2,GORASP2,CCNB1,BET1L,PCDHB13,NR2E1,RAN,CCDC47,MTX2,SSRP1,CLDN12,SETD4,CUL3,KCND3,CEP85,NF2,CAPZA2,PRRT1,HIGD2A,GTF2E1,NDUFB4,AP2S1,LLPH,ARHGEF6,EMC8,CFAP73,PRND,B9D1,VPS39,MIR182,ELAVL4,TAPBPL,CLP1,PPP3CA,FAM107A,SLC6A1,ACP2,ITGB5,AKT1,KCND2,NUDCD3,TNFAIP3,RBBP4,NEUROD6,MT3,TOX,ROMO1,DKC1,UCP2,ENY2,ABCB1,ATP6V1G2,SKIC8,NSG1,CALR,PHF1,PSMG2,HIGD1C,MSH6,RND2,FHIP1B,FAS,FLRT3,ANP32B,KIT,CDK5RAP3,CCDC69,KRT7,TFG,TSG101,KCNS1,PLA2G5,PRNP,OXSR1,IQSEC1,SF3B4,SLX1A,EMC10,SMN1,FAM149B1,DAPK3,AKT2,ATXN10,PDLIM4,SCLT1,MPV17,UHMK1,TMED1,HEXA,BAX,RTP4,LAMP2,IL6,CEP19,MMP9,ZMYM4,ACAA2,DEGS1,RAB23,G3BP2,ACVR1C,GPM6B,KLHDC8B,DDX1,OCRL,SLC39A9,SELENON,LPCAT3,DTD1,MLLT6,MCL1,RPL10,VPS18,GABPB1,UCN,TAPBP,MNS1,MED27,DRP2,NCAPG2,GTF2A1,SSBP3,CCDC65,TMEM95,MAD2L2,MGME1,PLEKHO1,CCSER2,EDNRA,EMILIN1,MED11,TBC1D24,EPHB6,ARHGAP12,MOBP,FITM1,CNN3,PLG,MZB1,IL1RAP,TOP2B,HMG20A,HFE,PFDN5,RHOU,BCL6,PHACTR1,NSFL1C,ELMO1,TOPBP1,SLC25A4,SEC13,TRAPPC14,LRRTM2,RUVBL1,PDIA3,OIP5,SLAIN2,CSRP1,HMGA1,ACTB,TNF,SHMT1,CAPZA1,SF3B1,RETREG2,ALDH1A3,FOXC2,TIFA,AIF1,CTSD,NEUROG2,SEC61A1,GJA1,MIR17,CNTN1,SNRPD1,RAB31,PRPF18,LRRC4B,SLC25A5,LRRC8D,RB1,RIOX2,FOLR1,NDN,RBM5,DRGX,TMSB4X,TSPYL4,CDK9,SDR16C5,TMEM14A,ZBED3,SPTSSB,HOMER1,TOR1B,TMED7,TMEM147,PIP4P1,TMEM165,ARF4,RPS15,ANO3,CHORDC1,GEMIN7,EMG1,TMEM38B,TRIP4,PCGF2,CRABP2,CIAO3,LAMB2,LARGE1,RAP2C,EPOP,TUBG1,TNFAIP6,SKA1,NEK7,SOD2,CNP,EHD1,ASCC1,MCM4,CSGALNACT1,PCGF6,PPFIA3,ACTL6B,DDX23,KCTD12,SDC4,CIAO1,VCPIP1,STK4,MAEL,SLC7A9,SLC16A1,DSTN,SGTA,KLHL22,HELLS,CD3G,IMPACT,MAPRE1,PPP2R1A,SUV39H1,NREP,CHMP5,RHOG,COA5,TNFAIP8L3,APOO,GABARAPL1,GPHN,B2M,CCSAP,LHX2,ATAT1,SAMM50,S100B,LUM,SIAH1,APOC2,GINS3,THAP7,ZNF501,SLC31A1,CXCL1,HCFC2,MSL2,RMI1,SPINT2,ATP6V1C1,COL3A1,DHX9,RPA3,SPP1,GJB1,RAB29,GABRG2,FBLN5,LCA5,RLIM,GTF2B,OSBP,SPATA6,TRAPPC3,BECN1,CBLN1,FMOD,DICER1,FIS1,RAB13,BANF1,DLG1,SF3B5,UBXN10,ABITRAM,STPG4,CFAP61,KCNIP2,PRMT2,HGS,ACTL9,HDAC5,FCGR1A,RABL2B,WDR11,NHP2,BUD23,MIR29C,KDM1A,RFX4,TLCD1,TSSC4,STX8,ATP6V1D,NDUFB7,CDNF,UNC119B,RNASEK,SRSF12,CCL3,RAB18,FHL3,MAP1LC3B,IFT172,FERMT2,CLDN22,GOSR2,PSMG4,RCHY1,IGF1R,PPIA,CDC42,LIMD2,ADD2,ZDHHC15,KCNC1,EFNA3,NELL2,IL2RB,EPHA4,RPL10L,ATP2C1,TMEM127,HTRA2,OPHN1,H2BC9,MYD88,NPTN,H1-10,VTI1B,SEPTIN7,THG1L,CLDN24,TYROBP,SSH3,FURIN,KANSL3,STK38,COX19,CLU,TMIGD1,MACROH2A2,MED30,SLITRK2,RAP1A,CLTRN,TEX264,ATG4A,CDH8,CRTC2,KCNJ10,EIF1AX,C2CD2L,RAB35,H2AZ2,NINJ1,NEK2,LAMTOR1,CD2AP,PLN,VPS16,GADD45A,MARCKSL1,TSPO2,NDP,RPL24,EIF2S1,NDUFB5,TERT,SSNA1,UBXN2B,FGF13,ALOX5AP,TASL,BMPR1B,SLC11A2,DISC1,HCLS1,PML,SNRPD2,CBR4,CFAP97D1,SRPRA,PHB2,COTL1,TM9SF4,MCM3,SNRPB,EPS8,KRIT1,SQSTM1,MGARP,MMP28,CALY,IGSF21,DAG1,C1QL3,SERPINH1,CLDN14,SMARCA5,TESK2,RAB8B,TMCC1,CHAMP1,METTL22,GOLGA5,ARHGAP5,DYNLL1,SEC23A,SNX10,MED17,PET117,TOMM7,BORCS5,ELFN1,SNX11,EIF3K,CLDN8,LYSET,TMEM199,TRAPPC4,TFE3,SEMA7A,LPXN,NCDN,PRMT6,COX17,MPV17L2,FBXO7,SMARCB1,EFHC1,SLITRK1,LSM4,INO80E,SMAD4,SEMA3C,AIF1L,PEX26,NOP53,PHETA2,ASZ1,NDNF,SLC1A1,CTNNB1,HYAL2,SHLD1,H2AC7,KLK5,COPS7B,CYFIP2,DR1,RPSA,TTL,PDCD10,EIF3D,PACSIN3,SS18,CRISP1,NUP153,STK26,ATP5IF1,RRN3,CDC42EP2,HPF1,CREBZF,LMO4,GRIA1,BLCAP,L1CAM,ASF1A,UGCG,FGD2,SMCHD1,CD34,ACACA,RAB27A,ABCE1,TUBA1A,MED31,MORF4L1,FBXL19,MIS12,LYZL6,MCPH1,JAK2,PTEN,VLDLR,STX7,USP3,CAND1,NEUROD2,SNAP91,PAK5,GPC4,TRAF7,MAP4,TOP3B,OTX2,NCKIPSD,HAS3,AP1S2,DMAP1,USP6NL,NDUFB6,KBTBD13,GCA,CSK,SLITRK5,ALCAM,LRRC4,KLHL24,CPNE1,ANAPC2,POC1B,TRAPPC1,COX7A1,CKS2,NOS1AP,DNM2,SMURF1,EMP2,MAEA,UBE2B,PMAIP1,BAP1,CD36,GJA10,SRSF10,NDUFS3,ARPC3,KHDC4,MED29,RPS23,NOA1,MLH3,TRAPPC6B,TIMM29,BCCIP,TRIM46,CXCR4,PYCARD,MAPRE2,HMGB1,BCL7B,GABRB3,ZDHHC8,PITPNB,KCTD11,DFFA,VPS28,EMC6,NTNG2,H2BC1,RAB6A,PTK7,TRAF1,TAGLN3,RFC5,CX3CR1,MIR145,CCM2,RAB2A,VAMP7,RAB6B,RAB11A,DDRGK1,ATPAF2,MMP21,RBBP7,ARMCX3,RAF1,CACNB3,STN1,PPIH,POMT2,RIMOC1,BCL7C,PLSCR1,TMEM126A,CDH11,HSD17B1,LMAN1,PRKCA,NEFL,WDR83OS,MCMBP,H1-6,TRAPPC10,EIF4E2,AZIN2,ASIC2,ADNP,CTTN,DNAL1,VAMP2,KCNA3,INPPL1,PEX3,HSP90B1,RFC4,SH3GLB1,USP16,TOMM70,DCLRE1C,DNAJC2,POLE3,EYA3,SRSF1,RAC2,TBCE,RRP7A,CHMP1B,ITGA6,SCN1B,COX10,ARHGAP21,RANBP10,ATG101,SKA2,LPAR1,ERCC3,ARF1,BCS1L,SVBP,TMEM30A,CLSTN3,EMX1,B4GALT6,GABARAPL2,LYRM2,TMED5,RABIF,F11R,SESN2,CALHM3,PRKCQ,TMEM237,ZNHIT1,YTHDF2,COA1,EZH2,UPF3B,CHRNA7,ADCK1,NR4A2,TRAK2,SRP54,IKBKB,EGR1,CHCHD4,MKKS,FANCG,DDIT4,PROX1,CREBBP,JCHAIN,WASF3,KCTD15,GCLC,WASL,EIF2D,ATP6V1G1,DYRK1A,TWNK,FGF10,TF,ADAMTS1,FBXL4,NCK1,CLDN9,KRAS,STBD1,DPY30,ADAMTS10,GTF2H5,PRM1,PICALM,PYM1,ADAMTS20,SLC35F6,PTTG1,ARHGAP25,NAP1L3,FEN1,CTNNA2,LRP12,MAP1LC3A,CLRN1,SUMO1,EEF2KMT,DIRAS3,SETD3,UBN1,HNRNPC,TTC8,CCT2,RER1,H2BC11,NLRP6,RETREG3,ACTN4,KLHL1,COIL,CAV2,MED21,EED,MTCH2,NAA50,ZMYM3,UBE2A,PWP2,KCNJ2,TRAPPC13,RPS6KA4,ATP6AP2,SSBP1,CDK1,SNIP1,RPL23A,MYC,SEMA6C,CDC20,FAF2,GOSR1,FITM2,CBLN3,PHF13,SNRPG,UBE2I,APOBEC3F,ATP1A3,CLDN1,PTN,GJC1,MTM1,GPR22,PSEN1,GABRB2,OR10A4,LIX1,TRAM2,ALKBH5,BRCA1,NAA60,BLOC1S3,ZYX,PIM2,RAB1A,AGAP2,TMEM70,PLEKHF2,ADGRL3,CAV1,MCOLN1,PRDX4,TNKS,MEAF6 |
| 5.932e-04 | -7.43 | MSL1 (MSL complex subunit 1) | protein interactions | 339287 | 65 | 31 | 19454 | 5460 |
HMGA1,MOV10,FRA10AC1,MORF4L1,RNF40,GMNN,HSPB1,H2AZ1,RAN,ZNF330,CDK9,TOMM70,CNTROB,ESR2,FCHSD2,RAF1,SOX2,CBX3,PNMA2,HBB,NUPR1,CRKL,PPM1G,HAPSTR1,RNF113A,UBE2D3,H3C1,NUCKS1,RNF20,MSL2,MDC1 |
| 5.932e-04 | -7.43 | MAGEB10 (MAGE family member B10) | protein interactions | 139422 | 65 | 31 | 19454 | 5460 |
RPL3,SLC25A11,RPS13,RPL17,BRIX1,MAGEC2,RPL4,STAU1,H2AX,ARHGAP12,RPL15,RPL26L1,RPLP0,SKA3,LLPH,PRKRA,NUDT9,RPLP2,RPL12,MRTO4,RPL32,UBP1,RSL24D1,RPL7,RPL7L1,RPF1,LYAR,RPL6,EPHA2,RPL10A,CDKN2AIP |
| 5.932e-04 | -7.43 | MPST (mercaptopyruvate sulfurtransferase) | protein interactions | 4357 | 65 | 31 | 19454 | 5460 |
HINT2,HINT1,CRYZ,POLDIP2,YKT6,HSCB,ZBED1,SRI,GLRX5,LAP3,CMPK1,SPR,SEC22B,GAMT,GSTP1,VAPB,DISC1,GATD3,ANXA4,ENO1,DDAH2,CLIC4,CTSB,TXNDC12,TAX1BP1,MTPN,CTSD,ACO2,PMPCA,FXN,PEDS1 |
| 5.932e-04 | -7.43 | TMEM41B (transmembrane protein 41B) | protein interactions | 440026 | 159 | 64 | 19454 | 5460 |
TUFM,PDE4B,LMNB1,RHOB,ATP1B3,VMP1,XPOT,CYB5R3,LMBR1L,UQCRC2,SLC1A1,GPR89A,SEC61A1,RHOJ,ESR2,PGRMC1,RABL3,CDC42,UQCRC1,SAMM50,TMEM115,LMNA,ARCN1,SLC25A3,DERL1,VIPR1,PHB2,SLC7A1,SLC5A6,PTDSS1,ATG7,XPO1,RHOG,STYK1,PPP2CB,PHB1,HACD3,STT3A,XPO5,DYNC1I2,RPL7,FZR1,ARL6IP5,HSP90AB1,ERLIN1,YTHDF2,IPO8,ERLIN2,LBR,EEF1A1,TMEM165,RPN1,TFRC,SFXN1,CCT8,SLC25A5,DHX9,SLC16A1,SLC2A8,RPL3,VDAC1,KRAS,RPS27A,SLC6A8 |
| 5.933e-04 | -7.43 | positive regulation of intracellular transport | biological process | GO:0032388 | 138 | 59 | 18204 | 5365 |
PIK3R2,HDAC3,MLC1,RIOK2,RAN,PIK3R1,RBM22,ANP32B,BAG3,JUP,EDEM2,SFN,BORCS5,CD81,MSN,CAMK1,FEZ1,PSEN1,HCLS1,JAK2,EDEM1,VAMP2,CHRM1,MECP2,MAVS,SAR1B,SNAPIN,NF2,MTMR2,NRDE2,PDCD5,IL1B,DMAP1,CDK1,DHX9,CALY,CTDSPL2,TRIM46,HSP90AA1,PRR5L,OAZ2,LEP,TM9SF4,STX18,STK11,MDM2,PDCD10,EP300,IFNG,TMEM30A,SMAD3,HYAL2,RAB29,OAZ3,EFCAB7,EHD1,OAZ1,NCBP2,CDC42 |
| 5.946e-04 | -7.43 | MED15 (mediator complex subunit 15) | protein interactions | 51586 | 121 | 51 | 19454 | 5460 |
RUVBL1,EWSR1,FHL3,TRIM11,PLSCR1,TRIP4,TOP2B,POLR2G,CDK8,MLLT6,RPAP2,SMAD1,MED9,NUP35,THOC1,IGBP1,CTDSPL2,SMAD3,UBE2N,MED4,HNRNPD,BRD3,MED21,MED27,MED29,MED11,FBXW7,NR1I3,MED13L,RPA3,PML,MED31,MED23,FBXL19,MED30,ELP3,CCL3,ATG16L1,ACTL6A,UBB,APEX1,ESR2,MED17,RBBP4,POLR2F,SMAD2,MED10,DCAF4,AR,MED22,CUL3 |
| 5.946e-04 | -7.43 | TLN2 (talin 2) | protein interactions | 83660 | 44 | 23 | 19454 | 5460 |
SEM1,RGCC,DGCR8,PRNP,TTC4,TRMT61A,VIRMA,CDC5L,SKP1,TRMT6,ZYX,SYNCRIP,CLK1,ALB,RAC2,SOSTDC1,HSPA13,HNRNPD,EXOC8,DCUN1D5,TOP3B,KBTBD4,DDX39A |
| 5.948e-04 | -7.43 | CDK8 (cyclin dependent kinase 8) | protein interactions | 1024 | 216 | 83 | 19454 | 5460 |
KRAS,HNRNPF,THRAP3,RNF20,GTF3C3,MNAT1,MDC1,PPP1R12A,CBX3,CDK8,TFCP2,POLR2C,SMARCB1,UBL4A,MTA3,TP53,MED9,ZMYM4,GTF2E2,SMAD1,HNRNPL,TOP1,POLR2I,SMAD3,LDLR,MED21,MED27,SKIC8,SNRNP70,MED29,MED4,HNRNPD,KPNA1,CDK12,PPM1K,TOPBP1,ERCC3,HMGA1,GTF2E1,TRA2A,MED11,MLH3,STK38,FBXW7,RADX,POLA2,BCL6,BMPR1A,PPM1G,PRIM2,TCEA1,MED13L,MED23,WWP1,MFAP1,SUPT7L,MED31,WDR77,CCND1,POLR1D,GTF3C4,CCNH,MED30,FBXL19,MED17,CBX5,POLR2B,SMAD5,DEK,BCCIP,ESR2,GCFC2,PRMT5,GTF2F1,MED10,TADA3,FTSJ3,BRCA1,SMAD2,MYC,CREBBP,MED22,AR |
| 5.968e-04 | -7.42 | Toll-like Receptor Signaling | WikiPathways | WP3858 | 32 | 21 | 5310 | 1910 |
TICAM2,TRAF6,TLR2,TLR4,TLR7,IKBKB,IRF3,NFKB1,TOLLIP,MYD88,TIRAP,IRAK4,TBK1,TLR3,TLR1,TLR5,TICAM1,TLR9,TLR8,IRF7,TLR6 |
| 5.970e-04 | -7.42 | MYLK (myosin light chain kinase) | protein interactions | 4638 | 101 | 44 | 19454 | 5460 |
TRMT61A,ESD,PRNP,SDHB,OSBPL8,HSPB1,DRG1,FKBP4,ISYNA1,RIGI,PTGES3,CAMK2G,XPNPEP1,PDIA6,MLC1,PPP1R12A,GDI2,E2F4,TP53,VIRMA,SRC,RPS20,ACAT1,STUB1,CTTN,OAT,UBE2H,LACRT,MYC,HNRNPAB,MRPL57,APPBP2,PGK1,PRDX6,RPA3,PRKCA,MYL6,RPA2,PAK2,KCTD12,PPP1CB,CDC42,PGRMC1,MYL12B |
| 5.972e-04 | -7.42 | mitochondrial transmembrane transport | biological process | GO:1990542 | 94 | 43 | 18204 | 5365 |
SLC25A24,SLC25A4,TOMM40L,TOMM40,CPT1B,SLC25A5,SLC25A1,SLC25A39,CPT2,GRPEL2,SLC25A28,UCP2,ROMO1,TIMM23,TOMM20,DNAJC19,MAIP1,MPC1,MRPL18,SLC41A3,SFXN1,CHCHD4,SLC25A26,TOMM7,SLC25A23,TST,SFXN2,TOMM70,TIMM21,SMDT1,SLC25A31,GHITM,GRPEL1,TIMM17A,SLC25A51,SLC25A3,SLC25A20,SLC25A21,DNLZ,SLC25A12,SLC25A32,HSPD1,AIFM1 |
| 5.973e-04 | -7.42 | SLFN11 (schlafen family member 11) | protein interactions | 91607 | 371 | 133 | 19454 | 5460 |
IMP3,HINFP,H2AJ,SNAPC5,CCT5,DDX42,CBX3,RAD23B,MAP1B,DHX9,H3C1,NUP107,KPNA2,HNRNPK,RPS13,H2BC14,PRDX4,EIF3E,H2AC6,MOV10,TIAM1,SNRNP70,MPHOSPH10,LDLR,DKC1,DBT,TMPO,CDC5L,SF3A1,RPS14,UBA52,CCNA2,RPA2,LMNA,H2AC7,ACACA,RPA3,BAP1,MYH2,PRPF4,HNRNPH2,TCEA1,EIF5B,AATF,HSPA5,NONO,PDCD4,UBE2H,RRP7A,CCNF,PSPC1,ZBTB33,RPS12,YES1,CKS1B,ANP32A,H1-3,SOX2,NUP153,PPP2R1A,TUBB4B,PLD3,SNRPE,HSPD1,RPL31,HNRNPA2B1,CCT8,RUVBL2,RPAP3,RPS24,SRSF7,HNRNPF,H1-6,G3BP1,KGD4,RUVBL1,NUP42,CCAR1,HNRNPDL,RFC2,ANP32B,PRDX1,HMGA1,DDX50,RIOX2,PPP2R5A,YWHAG,EIF3D,SIAH2,KDM2A,VCPIP1,RB1CC1,SP2,XPO5,HNRNPL,RPS10,SPTAN1,TCP1,SNRPA1,PPIA,DHX15,NUP35,CCT7,ACTL6A,H1-5,USP39,EIF4B,MYL6,DDX39B,SPECC1L,HSPA8,SF3B1,NUP50,GPC1,RRN3,CUL3,LDHB,CCT2,H2AZ2,BRCA1,LMNB1,FTSJ3,YWHAZ,HSP90AA1,CPSF1,FAU,TRMT11,GTF2F1,TUBB,RBBP4,HECW1,SNRNP40,ESR2 |
| 5.977e-04 | -7.42 | ALDH1L1 (aldehyde dehydrogenase 1 family member L1) | protein interactions | 10840 | 34 | 19 | 19454 | 5460 |
PSMC4,PSMD1,AGR2,PSMD14,HSP90B1,HSP90AA1,PSMC3,UBE2H,STUB1,BAP1,CCNF,HAPSTR1,PSMC5,APPBP2,HSCB,PRNP,FBXO22,PSMC1,PSMD12 |
| 5.977e-04 | -7.42 | DBR1 (debranching RNA lariats 1) | protein interactions | 51163 | 34 | 19 | 19454 | 5460 |
CWF19L1,CLK1,EP300,RPA3,CAND1,FZR1,KRAS,SPTAN1,KCTD17,XPO1,TULP3,BAG3,RAF1,DHX38,TP53,UBE2H,RIT1,CSNK1A1,RPA2 |
| 5.977e-04 | -7.42 | UBD (ubiquitin D) | protein interactions | 10537 | 34 | 19 | 19454 | 5460 |
BIRC5,PSMC3,NAA15,TP53,TOR1AIP2,EEF1A1,HDAC6,CAV3,CTNNB1,PSMD4,USP16,AIPL1,MAD2L1,SRPK2,RIGI,PDE9A,PSMB4,PSMA6,SQSTM1 |
| 5.977e-04 | -7.42 | ACP5 (acid phosphatase 5, tartrate resistant) | protein interactions | 54 | 34 | 19 | 19454 | 5460 |
SELENOF,OGFOD3,SPP1,RPA2,EGR2,GPC4,CALR,PDIA3,SLC35F6,OS9,HSPA5,TNFSF10,PDCD5,ZBTB16,SNRNP40,GANAB,KLHL15,ACP5,PPP2CB |
| 5.977e-04 | -7.42 | E6 (protein E6*;transforming protein E6) | protein interactions | 1489078 | 162 | 65 | 19454 | 5460 |
RPL10,UBB,TAX1BP1,PSMD4,PSMC5,DLG4,DTL,KLHL1,TADA3,PSMD14,DCAF4,TFDP2,SNTA1,POMP,RNF40,IRF1,TRAF3IP2,PSMD1,ARHGAP21,ATF4,MYC,CREBBP,TRIM32,POLDIP2,ASB3,IRF7,EP300,RAB40AL,PML,IRF3,LIN7C,RAG1,PALS2,CDKN1A,SIPA1L1,LNX2,PSMC4,KCTD3,USP46,PSMB1,PSMB5,USP15,CDC23,PSMD7,ECD,TRAF6,SMAD4,KLHL22,TAX1BP3,PSMD3,KLHL9,SYNJ2BP,RNF26,RFC2,MNAT1,FEM1C,PTPN4,UBE3A,DLG1,KLHL25,KLHL23,PSMC3,KLHL26,DLG3,TP53 |
| 5.984e-04 | -7.42 | PRRC2A (proline rich coiled-coil 2A) | protein interactions | 7916 | 349 | 126 | 19454 | 5460 |
FUBP3,PHB1,PEG10,MRPS35,WWP2,CNOT2,IFI16,HNRNPA1,CPEB1,DRG1,ANKRD50,PABPC1,LSM14A,ZC3H7A,EWSR1,G3BP1,CHCHD2,DPM2,RERE,SSRP1,SECISBP2L,B3GNT2,RAF1,TOP3B,LGR4,JUN,PNMA2,TMEM14B,RPS11,ATXN1L,CPSF1,SPCS1,EIF4A2,APEX1,TCEAL7,MAD2L2,RPL19,CUL3,MYC,YWHAZ,FBXW11,MCRIP2,PSMA3,P4HA2,HSPA8,YTHDF1,SSR3,STAU1,FXR2,PSENEN,G3BP2,EHHADH,WDR77,LARP4B,EIF4E2,SYNCRIP,MRPS9,FZR1,CAND1,RPS16,MRPS23,RBM42,ZNF24,MOV10,GRSF1,TMA16,SNRNP70,H2AC4,UQCR11,GARRE1,RUSF1,HAPSTR1,CNOT7,SEM1,ERLEC1,EIF3E,CNOT6L,YTHDF2,TNRC6C,TP53,H2AJ,MAP1LC3B,SRP72,METAP2,EZH1,SMAP2,PSPC1,CCNF,RPS20,MRPS28,GANAB,FGFBP1,IFI6,SRPK2,VIRMA,CEP85,GORASP2,ANAPC15,RUNX1,H2BC9,RC3H2,EIF3G,MAPRE1,CASC3,UBE2H,IGF2BP1,PEA15,SIRT7,BAP1,RPA3,SQSTM1,SMG5,RNF113A,LSM12,RPL4,AATF,TPT1,SUMO1,ATG16L1,RBFOX2,RBMS2,PRMT2,AGO1,GRM2,RPA2,MRPS34 |
| 6.011e-04 | -7.42 | GOLGA4 (golgin A4) | protein interactions | 2803 | 210 | 81 | 19454 | 5460 |
LAMTOR1,NAPA,ATP5MC3,RAB2A,CSK,MYC,RAB11A,PSMD1,DNAJC5,TXN,ADRM1,BMP1,PSMD6,VIRMA,USP5,KTI12,PRMT5,SNRPD2,PSMC5,PSMB7,TMOD1,ARL15,KRT7,ACACA,PIH1D1,ZER1,BET1,RND2,FAXC,RAB6A,SGF29,SMC4,PXMP2,STX7,PSMC1,HSPA5,BAP1,XRCC5,RAB9A,PSMA3,RHOG,PSMD10,PSMD7,HNRNPD,LAMP2,MOV10,ATG9A,PSMD3,LAMP3,YWHAH,EXOC1,TPM3,HNRNPL,CCAR2,RHOH,DIRAS3,STX6,MYL12A,TNIK,PPP2CB,GJA1,RAC2,EZH2,RAB4A,ACADSB,FURIN,PSMC3,METTL26,PPP2R1A,MSX2,UBR7,PSMA2,RBBP7,HNRNPF,RUVBL1,KPNA2,S100A10,PSMD12,TMT1A,PABPC1,RUVBL2 |
| 6.016e-04 | -7.42 | SBDS (SBDS ribosome maturation factor) | protein interactions | 51119 | 165 | 66 | 19454 | 5460 |
IDH1,DHX9,RPL3,HNRNPA2B1,PRPS1,SRPRB,CAMK2G,KRAS,GTF2E2,TP53,NDUFA2,RPL18,ACOT13,EZH2,CHAMP1,MAP1LC3A,TYMS,RPL12,RPL8,ZBTB2,EGLN3,RPL7,RPL35A,COPS5,RPL6,CLIC2,AGPAT1,IGFBP4,SMAD4,NUP50,DDX5,XRCC5,PPM1G,UNC45A,STX7,STAU1,RPL4,MND1,SNRNP27,PAFAH1B1,SPR,ATG16L1,ACACA,RPLP0,STOM,LMNA,RPS3,MRPL53,NIPA2,RASL11A,JUNB,MED17,SNX3,PNP,GORASP2,CAV3,TOMM40,RPL7A,CUL3,CARS1,FGFR1OP2,MYC,RIT1,IGF2BP1,BRCA1,CYP1A1 |
| 6.040e-04 | -7.41 | skin-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-malignant_melanoma-superficial_spreading | 31 | 18 | 16828 | 4835 |
CTNNB1,KIT,MET,RB1,TP53,NF2,AKT1,JAK2,FGFR1,PIK3CA,TERT,PTEN,KRAS,HRAS,GNAQ,STK11,SF3B1,EWSR1 |
| 6.049e-04 | -7.41 | POLR2L (RNA polymerase II, I and III subunit L) | protein interactions | 5441 | 168 | 67 | 19454 | 5460 |
KRAS,ZBTB14,DNAAF10,PDRG1,IMMP2L,RPAP3,FAM168A,POLR2G,POLR2C,RBPJ,POLR2D,IMP3,SUPT5H,RPAP2,PSMB9,THAP1,POLR3F,POLR2I,EGLN3,RPRD1A,LDLR,MED27,MED21,MED29,SNRNP70,AGR2,CBL,MED4,WWP2,POLR3GL,FBXW7,STAU1,CDSN,COIL,POLR1H,SNRPA,RCCD1,ELOF1,EP300,RPRD1B,PIH1D1,TPT1,CCN3,MED30,POLR1D,MED17,POLR2B,SRC,PSMA6,NFKBIB,GPN2,POLR3B,POLR2F,POLR3H,MED10,ATG3,PFDN2,RIT1,POLR1B,PFDN6,HTRA2,LMO2,MYC,CUL3,RRN3,CCDC85B,SNRPB |
| 6.053e-04 | -7.41 | NT5C3A (5'-nucleotidase, cytosolic IIIA) | protein interactions | 51251 | 87 | 39 | 19454 | 5460 |
RAB11B,EGLN3,RAMP3,DPEP1,HDHD5,LMBR1L,CCNF,COQ8A,GATD3,MTAP,AGPAT1,HTRA2,SLC6A1,PYCR2,BAG3,TUFM,DESI1,RNF115,NDUFS2,IMMP2L,RPA3,AKAP1,NMRAL1,STX17,GHITM,ACAA2,BZW2,ADSS2,NUDT19,RPA2,GNAQ,GFM2,CCR1,TP53,PCK2,NDUFAB1,CDC42,IDH3B,SOX2 |
| 6.053e-04 | -7.41 | MAN1A1 (mannosidase alpha class 1A member 1) | protein interactions | 4121 | 87 | 39 | 19454 | 5460 |
TRAPPC13,EPO,P3H1,EZH2,CBLN4,CFTR,GPC4,TMEM59,TMEM106A,B3GNT2,GINM1,CLU,CLDND1,UST,CLEC12B,CD1B,SLC39A3,HAPSTR1,SLC39A9,RAB1A,CBL,HNRNPD,IGF2BP1,EPHA2,TRAPPC2L,BPNT2,GORASP2,FAM241A,HSP90AB1,VIRMA,NLGN2,B4GALT3,LRRC24,RAB1B,PTEN,EED,NRSN1,LMBR1L,ARF1 |
| 6.053e-04 | -7.41 | ENO3 (enolase 3) | protein interactions | 2027 | 87 | 39 | 19454 | 5460 |
TFCP2,FKBP1A,HEXIM1,SOD2,PGM1,SNAPIN,JUN,EEF1A1,TRIM63,HSPE1,FKBP2,ATP5PF,MAP1B,SOD1,HINT1,HSD17B10,TAGLN3,GPX4,PGK1,HSPB2,NME2,SPOP,FKBP1B,PGAM1,CALR,GAPDH,HSPB8,PPIB,SPPL3,TCAP,TXN,TAGLN2,APEX1,ENO2,ENO1,DLST,FABP5,AKR1B1,RB1 |
| 6.063e-04 | -7.41 | RAI14 (retinoic acid induced 14) | protein interactions | 26064 | 204 | 79 | 19454 | 5460 |
AIPL1,FBXO22,RPGRIP1L,RHOJ,NDN,ESR2,DYRK1A,UBE2V2,SH3BGRL,CTTN,CCNF,PHF21A,RHOB,YWHAZ,H1-1,NRP1,RAB11A,MYC,PPP1CC,USP14,BTF3,CAV3,FBXW7,KDM1A,PACSIN3,HSPA5,STX7,FOS,RPA3,DDX39B,RHOU,BAP1,RAB5A,SQSTM1,HSPA8,FGFR1,RPA2,VAPB,STAMBP,PPP1CB,CDC42,CGAS,RHOH,HNRNPL,CAV1,STX6,PTP4A3,FEZ1,RAB35,SNRNP70,RHOG,UQCR11,YWHAB,ANKRD50,MED4,VPS26A,KXD1,IFI16,YWHAH,YWHAG,VDAC1,ERLEC1,TNF,KRAS,MDC1,FLOT1,DPM2,RIGI,FBXO25,TEDC2,PPP1R12A,CHMP4C,CAPZA2,TFCP2,FURIN,PSMC3,RAF1,SOX2,ISG15 |
| 6.077e-04 | -7.41 | ARPC2 (actin related protein 2/3 complex subunit 2) | protein interactions | 10109 | 171 | 68 | 19454 | 5460 |
RIGI,CAPZA1,ANP32B,TRIM37,KRAS,THG1L,PPP1R12A,NUPR1,SH3GLB1,ACTR2,TMEM165,NFE2L2,ARPC3,CAPZA2,EZH2,EEF2,MAP1LC3B,SOX2,ACTN4,TOP3B,B3GNT2,TMPO,ARL6IP5,YWHAB,AGR2,ARL14EP,ACTR3B,HDAC6,BCL7C,XPO1,ATG7,PFDN5,EMC4,STAU1,UFL1,STK26,SPECC1L,RPA3,SMARCD3,PPARG,RPA2,CFTR,PPP1CB,CDC42,SUMO1,LAP3,ESR2,TNPO3,CEP97,SH3BGRL,TOM1L1,ACTB,DAPK1,EFHD2,CTTN,ACOX1,UBE2H,VMP1,CALU,MAPRE1,BICD2,NIF3L1,BAG3,USP14,BTF3,ARL6IP6,PRKACB,MYC |
| 6.084e-04 | -7.40 | NUP98 (nucleoporin 98 and 96 precursor) | protein interactions | 4928 | 201 | 78 | 19454 | 5460 |
GTF2H5,RPA2,LMNA,SSR1,SEC62,OTULINL,NUP62,TOMM20,B9D2,DERL1,EP300,NUP50,RNF113A,RPA3,CD40,SIRT7,ANAPC4,XPOT,CDC73,PIM2,PTTG1,MAPRE1,RIT1,SPOP,LMNB1,BICD2,H2BC9,CREBBP,SEC13,CDC20,MAD2L1,DYRK1A,VIRMA,ESR2,SRP54,SEC61B,PTPMT1,UBE2I,LMBR1L,RAN,FAM136A,PARP11,NUPR1,GLE1,STIM1,EZH2,DISC1,HDAC11,NUP153,NUP37,TNPO2,COMTD1,TBK1,RANBP1,TP53,RIGI,NUP107,KRAS,G3BP1,HAPSTR1,FAF1,TMT1A,CSNK2A1,XPO1,CTNNB1,IFI16,NCBP2,CDK9,TMPO,NUP35,FZR1,XPO5,HSD17B11,EED,ETV6,PTPN1,FBXO32,RCHY1 |
| 6.098e-04 | -7.40 | EAF2 (ELL associated factor 2) | protein interactions | 55840 | 39 | 21 | 19454 | 5460 |
DDX39A,XPO1,SIAH2,CSK,LNX2,TP53,STAC3,SSX2IP,TFIP11,TRIM23,BIRC2,SYT2,TCEA1,TFPT,DVL2,PNMA1,TCEA2,EAF2,RBBP7,RBBP4,CCAR2 |
| 6.098e-04 | -7.40 | GNLY (granulysin) | protein interactions | 10578 | 39 | 21 | 19454 | 5460 |
RBM27,ARMC8,BCL2L1,YPEL5,DDX50,KLHL9,ZMYND19,FBXO7,LBR,GRPEL2,CHCHD2,POLDIP2,KBTBD6,RANBP10,MAEA,GID8,GID4,RBM23,RMND5B,LRRC1,MKLN1 |
| 6.098e-04 | -7.40 | MS4A3 (membrane spanning 4-domains A3) | protein interactions | 932 | 39 | 21 | 19454 | 5460 |
TM4SF18,TMEM182,SMCO4,CDKN3,TMBIM6,SEC22A,CCDC167,TMEM107,ADIPOQ,CLDN6,EFNA5,PLPP6,VKORC1L1,PLP1,TEX264,STX8,EMP3,SGTA,CLDN1,ATP6V0B,ERG28 |
| 6.099e-04 | -7.40 | ANO6 (anoctamin 6) | protein interactions | 196527 | 124 | 52 | 19454 | 5460 |
ST7,OTULINL,SEC62,CDC42,CHRNB2,SSR1,RAB9A,MIA2,DERL1,HSPA8,PXMP2,STX7,RAB11A,RAB2A,CDC16,ANAPC4,LGALS8,RHOB,SEC61B,SYNGR1,VAMP3,S1PR4,VIRMA,POPDC2,SLC51A,DNAJC25,PREB,RAB4A,RPN1,TAS1R2,RNF133,TMT1A,SAR1B,ARF4,PDE2A,KRAS,LAMP3,RAB5C,CDC26,LAMP2,BCL2L1,UPK1A,LRRC8B,CDC23,RHOG,RAC2,GJA1,HSD17B11,RAB35,DNAJC1,MARCHF4,ARF6 |
| 6.115e-04 | -7.40 | PELP1 (proline, glutamate and leucine rich protein 1) | protein interactions | 27043 | 177 | 70 | 19454 | 5460 |
RCHY1,LDLR,RB1,MAP1LC3A,SUMO2,CGAS,SPPL3,ZBTB2,TAF7,NFKB1,IFI16,DDRGK1,ZMYND11,ATG7,H2AC4,TRAF6,RPS2,SMAD9,EWSR1,RPL3,RUVBL2,RUVBL1,G3BP1,KRAS,H3C1,TP53,MAX,TOP3B,LGR4,H2AX,JUN,SOX2,H2BC1,CHMP4C,EZH2,HGS,METAP2,EIF2AK2,CCNF,PTEN,FGFBP1,SNRNP40,SRC,SRPK2,RPL10,TOM1L1,CREBBP,MYC,AR,RPL26,PRPF31,ATG3,CHTOP,H1-1,UBE2H,PML,SIRT7,PRKD3,RPA3,EP300,HSPA8,KDM1A,NPM3,UFL1,PIP5K1A,SYK,H2AB1,GRM2,RPA2,RPLP0 |
| 6.116e-04 | -7.40 | CD2AP (CD2 associated protein) | protein interactions | 23607 | 195 | 76 | 19454 | 5460 |
UBE2I,MSN,PSMC5,CTTN,CCNF,VIRMA,SRC,ATP6AP2,ACTB,YES1,RPGRIP1L,STAT1,RACGAP1,GALE,UFD1,SFN,CUL3,AKT1,TAS2R7,UBE2H,MAPRE1,PFDN2,IGF2BP1,BICD2,MYO6,CIRBP,PRDX6,HSPA8,PML,INPPL1,RPA3,BAP1,RNF41,STAP1,STAU1,SGF29,NF2,CERS2,KDM1A,MRPL12,CD2AP,RPA2,FRS3,LMNA,TSG101,DNM2,CD2,PRNP,HNRNPL,YWHAH,CSNK2A1,YWHAG,MMUT,CIAO3,INO80E,PIK3R1,CBL,NAB2,MED4,H2AC4,SOS2,SCPEP1,HNRNPA2B1,ZYX,CAPZA1,PTGES3,UBE2A,PSMB10,HUWE1,DPH5,ARFGAP1,KBTBD4,MTA2,HBP1,RAB4A,CAPZA2 |
| 6.116e-04 | -7.40 | SGPL1 (sphingosine-1-phosphate lyase 1) | protein interactions | 8879 | 195 | 76 | 19454 | 5460 |
UNC50,ERG28,LRRN4CL,STX8,IMMP2L,SAR1B,VDAC1,DIPK1A,MFSD6,TMEM176A,CCDC47,ATP5PB,MTCH2,CRELD1,OTULIN,SEMA7A,CYB5B,AQP3,FA2H,AIFM1,RAMP3,TMEM97,WIF1,FZR1,RPS16,EIF2B5,DDRGK1,FAM20C,ATP5MG,PLPP4,MARCHF5,WWP2,MED21,SCAMP5,SNRNP70,DERL1,RNF113A,DVL2,CXCR4,PEBP1,PPM1G,RPA3,FBXW7,SEC62,PLP2,OTULINL,ST7,CFTR,ATG16L1,CYC1,ATP5PO,RPA2,LRRTM3,GP9,CSNK2B,SEC61B,BAD,VDAC2,FAM177A1,CCNF,CYB5R3,APLNR,UQCRQ,TECR,EFNA5,ESR2,RPL10,SRPK2,TOMM40,HMOX2,MYC,TM9SF4,GPBAR1,MORF4L1,NRP1,UBE2H |
| 6.127e-04 | -7.40 | TMEM59 (transmembrane protein 59) | protein interactions | 9528 | 180 | 71 | 19454 | 5460 |
GOSR1,RHOU,BMPR1A,CXCR4,TIMP3,LRP10,SQSTM1,ZMYM6,LMBRD2,FGFR1,ATG16L1,GJC1,CNPY3,MGAT1,B4GALT3,YES1,RHOJ,ESR2,ALG5,DYRK1A,B4GAT1,LMBR1L,LRP12,B4GALT1,GPR89A,RHOB,TRIM32,TMED4,CSGALNACT2,DNAJC5,PGAP4,CD1B,B4GALT7,TOLLIP,FKRP,CALHM2,UST,FASTKD5,GALNT2,STX8,FKTN,GLCE,EFNB1,MAN1A2,TMEM59L,SFTPC,ENPP4,UGCG,SYNGR3,IL20RB,POMT2,ERRFI1,B3GNT2,CBLN4,DIPK1A,SPPL3,RHOH,TOR1B,SLC25A17,B4GALT6,GLT8D1,GJA1,FUT1,NRSN1,RNF128,EXT1,RHOG,CHST11,TMEM30A,DPP4,CFC1 |
| 6.127e-04 | -7.40 | YTHDC2 (YTH N6-methyladenosine RNA binding protein C2) | protein interactions | 64848 | 192 | 75 | 19454 | 5460 |
RC3H2,DCAF4,FBXW11,MYO6,PSKH1,UBE2H,HSP90AA1,ZBTB38,RPL7A,CUL3,MYC,ZNF668,FBXO22,RPL7L1,RPL13A,ESR2,SRPK2,RPL19,CCNF,RPS3,PSPC1,TRIM24,PTEN,GSK3A,FGFBP1,PRKRA,GRM2,APOBEC3C,RPA2,RPL26L1,HEXIM1,RPLP0,ZNF574,H1-5,RPS14,ATG16L1,PABPC5,RBMS2,FGF13,STAU1,RPL4,NOP53,UFL1,TRIM52,SIRT7,RPA3,SNRNP70,GSTO1,RPL10A,WWP2,IRF4,IFI16,GRSF1,DDRGK1,COPS5,CGAS,RPS16,CAND1,RPS10,FZR1,SURF6,RPL8,SYNCRIP,PRR3,LLPH,RPL15,SOX2,RPL17,IMMP2L,PTGES3,RPL28,FGF3,RPL31,RPL3,RPL23A |
| 6.127e-04 | -7.40 | VIPR2 (vasoactive intestinal peptide receptor 2) | protein interactions | 7434 | 192 | 75 | 19454 | 5460 |
SERINC1,RETREG3,SLC30A7,GPR89A,ATP5F1B,SLC25A4,REEP4,SC5D,VKORC1L1,TNPO3,VIRMA,TMEM41A,KDSR,VEZT,ATP5F1A,NCAPG2,HMOX2,ATP1A3,HSDL1,CXCR4,VIP,DERL1,SLC35F2,MAVS,CERS2,CYFIP2,CMTM6,ZDHHC17,DAD1,CERS6,FABP4,RABL3,SYNGR2,FAM234A,DUSP14,EFHD1,COQ8B,SLC19A2,HACD2,LMBRD2,ATP5PO,GHITM,VPS18,STOM,ELOVL1,CAV2,MPDU1,ADGRG1,XPO5,SNX17,ADCK1,COG1,NOP9,AIG1,MSMO1,ORC5,EI24,SYNJ2BP,FAM241A,FAM241B,TMEM164,FITM2,RINT1,PGAP4,ATP5F1D,CSNK1E,ATP5PB,YIPF3,YIPF4,TNPO2,SURF4,SLC35F1,BZW2,KDELR1,OTULIN |
| 6.127e-04 | -7.40 | regulation of system process | biological process | GO:0044057 | 571 | 204 | 18204 | 5365 |
DES,RNF10,G6PD,KCNJ3,NLGN2,DMPK,CD38,PRKCA,GJA1,PLN,MIR17,MIR214,SCN2B,IGSF11,CTTN,FGF13,TNNC2,SRI,ASIC2,CHRM3,KCNJ8,EHD3,NHERF1,NPSR1,AGER,NKX3-1,TBC1D24,MIR208B,STX1A,RGS2,ORMDL3,RANGRF,TMIGD3,GPR171,CCN3,AVPR1B,CRHBP,TMEM108,ATP1A1,MIR145,EIF4A3,DBH,SMAD3,SCN3B,ROCK2,PARP2,STC1,ADIPOQ,TNF,MIR153-1,OPRK1,PPARG,TNNI1,JUP,KCND3,MIR30E,PI16,GSTO1,GTF2IRD1,TSPO,PDE9A,CHRNA7,BMPR2,MTPN,MYRF,FABP5,MECP2,C1QTNF1,PDE4B,PIK3CG,LEP,DLG4,NETO1,TOMM70,PTPN11,MIR34C,DAG1,ADORA3,SRC,ADRA1A,ADORA1,FGFR1,TMEM38B,MTMR2,TACR3,MIR143,ROCK1,RAB8B,SCN1B,MEF2A,MIR1-1,NLGN1,FIG4,CTSC,TNNT2,MIR34B,CACNB2,MDM2,ATP1A2,CARTPT,SLC8A1,SOD1,DLG1,BECN1,TNNI3K,TRIM63,DICER1,ATP1B1,CBLN1,TNR,KIT,MIR20A,GHRL,MIR448,SUMO1,CRHR1,SETD3,CRY1,CHGA,GSK3A,KCNIP2,NR1H2,ATP2B4,OR51E2,MIR200C,PTEN,HAND2,ASB3,ADRB2,ITGA2,WASF3,SMAD4,TPPP,KCND2,GSTM2,MIR25,SPP1,LMNA,PPP3CA,WNT7A,NPVF,OXTR,RETN,FGF10,SLC1A1,TGFB2,CAMK2G,HRH2,IGF1,MIR21,MIR30B,MTG2,LPCAT3,HBEGF,INHA,EGR2,GJC1,ATP1A3,SELENON,KCNMB2,TACR1,NOS1AP,TNFRSF1B,MIR208A,ZMPSTE24,ADM2,EMP2,GPR35,MSTN,CAV3,UCN,FKBP1B,HTR1A,MTG1,EDNRA,CLIC2,CAV1,PPARA,FGF12,DAPK3,GRM1,SNTA1,BVES,IL6ST,HEY2,ADRB1,HSP90AA1,REN,INPP5K,ENO1,HTR2A,TRPC1,APLN,KCNJ2,CCL3,GNAO1,DLGAP4,POPDC2,FBXO32,KBTBD13,GLRA1,HCRT,FOXP1,TMEM100 |
| 6.133e-04 | -7.40 | PLEKHF2 (pleckstrin homology and FYVE domain containing 2) | protein interactions | 79666 | 189 | 74 | 19454 | 5460 |
NUDT2,ZBTB6,SEPTIN6,RTN4,TRIM22,RABAC1,RADX,MARS1,LDOC1,UGP2,TRAM1L1,EEF1E1,CHIC2,RPE,FGF13,TBCEL,MAP2K1,SOST,NDUFA5,MFAP1,RARS1,RAB28,SPEF1,AP2M1,CAVIN2,FAH,CUL2,PIK3R3,SFN,ZNF250,ZDHHC24,NONO,DRAP1,CCDC85B,CRYBA1,GTPBP2,CCDC25,TNFAIP8,GLUL,THG1L,FHL3,YIF1A,BSCL2,PRPSAP1,FRMD8,CHCHD2,PAK1IP1,GNMT,ZNF263,MAX,ZNF581,RPAP2,PRKAG1,TNFAIP8L1,CERK,GPBP1L1,THOC2,RPRM,TRAPPC3,RGS10,TSC22D3,TTC9C,MEAF6,PPP1R18,CCDC172,CGGBP1,HEBP2,GSTM3,KARS1,MOV10,TRAF6,ARL14EP,YWHAB,STAMBPL1 |
| 6.133e-04 | -7.40 | MYO1E (myosin IE) | protein interactions | 4643 | 189 | 74 | 19454 | 5460 |
SH3BGRL,UBE2V2,SMURF1,SRPK2,VIRMA,ESR2,DYRK1A,CAVIN2,RBBP4,LGALS3,ACTB,SNRNP40,RHOJ,ENO1,CTTN,PARP2,SP1,MAPRE1,RHOB,H1-10,PDE4B,ARHGAP21,BTF3,PPP1CC,SMARCA5,MYC,CREBBP,UNC45A,FBXW7,STAU1,STK26,RPA3,RHOU,RPA2,ISOC1,PPP1CB,CDC42,PAFAH1B1,CDK9,PTP4A3,NUP35,CAND1,SPTAN1,RAC2,CTDSPL2,H2AZ1,CNN3,ANKRD50,RHOG,YWHAH,HDAC6,IFI16,MOV10,H2AC14,MICB,EMC4,RNF20,RPS27A,KRAS,RUVBL1,TRIM37,THRAP3,RUVBL2,S100B,MAP1B,CBX3,CHMP4C,CAPZA2,SOX2,H1-3,ISG15,TOP3B,RAF1,FBP1 |
| 6.139e-04 | -7.40 | DSP (desmoplakin) | protein interactions | 1832 | 387 | 138 | 19454 | 5460 |
GAPDH,COPS5,HDAC6,TUBG1,MAP4,EFNA3,CTDSPL2,CD274,PREP,CAND1,G6PD,CDC5L,TP53,TNRC6C,INSIG2,DUSP1,EEF1A1,TFCP2,TNFAIP8L1,RNF8,NEDD8,PSEN1,CIAO1,FOXA3,AKT1,AR,USP14,TUFM,H2BC9,STK24,RC3H2,UBE2H,CDC73,GAB1,CCNF,PTEN,CALML5,GANAB,PRKCE,NDN,VIRMA,SMURF1,TECR,WDR5B,WSB1,CFTR,CDC42,METTL14,STX17,JUP,RPA2,CDK1,WTAP,PRKCA,RARS1,HEXIM1,SIRT7,NLE1,BAP1,RPA3,RNF113A,MTDH,NUCKS1,KDM1A,GTF2I,HSPA5,PIAS1,PTDSS1,GSTM3,PDIA3,HMGA1,YWHAG,HNRNPA1,YWHAH,AGR2,FKBP4,NCK1,AK2,CSTA,DCAF11,FABP5,CLK4,KRT8,EED,WDR82,RAB1B,HNRNPL,NPC2,HSP90AB1,CNTROB,RAF1,MSX2,EEF2,SOX2,PDHA1,CHMP4C,NME1,EZH2,MOB3C,RND3,HNMT,PABPC1,HNRNPA2B1,JAK1,TRIM37,G3BP1,HNRNPF,CUL2,PSMA4,HNRNPC,PKP4,CUL3,MYC,CASP4,BTF3,PSMD14,BRCA1,CCT2,CDKL2,COP1,RAN,DLST,PHF21A,SMU1,DYNLL1,RBBP4,DES,TOR1AIP2,PAFAH1B1,H1-5,DET1,SEC22A,PPARG,PIH1D1,EIF4B,PEBP1,DDX39B,HSPA8 |
| 6.145e-04 | -7.39 | UBQ-conjugating_AS | interpro domains | IPR023313 | 26 | 16 | 18521 | 5414 |
UBE2B,UBE2E2,UBE2E3,UBE2I,KRAS,UBE2H,UBE2A,UBE2K,UBE2M,UBE2D1,UBE2D3,UBE2S,UBE2L3,UBE2N,UBE2G2,UBE2F |
| 6.148e-04 | -7.39 | sensory perception of pain | biological process | GO:0019233 | 65 | 32 | 18204 | 5365 |
OPRM1,ITGA2,GRM1,LXN,OPRK1,CXCR4,CCR2,BACE1,RETREG1,HTR2A,CXCL12,KCND2,ADORA1,NLGN2,CDK5,KCNA2,NPY1R,MME,COMT,PNOC,OPRL1,PTGES,CHRNB2,HOXB8,MRGPRX2,NDN,MECP2,NR2F6,TNF,TAC1,DISC1,CCL2 |
| 6.148e-04 | -7.39 | regulation of endothelial cell apoptotic process | biological process | GO:2000351 | 65 | 32 | 18204 | 5365 |
MIR590,MIR375,SEMA5A,FASLG,CD40LG,MIR30B,KRIT1,MIR495,RGCC,MIR30E,NDNF,IL4,CD40,ANGPT1,MIR132,SCG2,CD248,TERT,MIR126,PDCD4,TNFAIP3,IL13,MIR15A,NFE2L2,TNF,CCL2,MIR106B,IL10,MIR125A,MIR101-1,MIR24-1,ICAM1 |
| 6.170e-04 | -7.39 | response to endoplasmic reticulum stress | biological process | GO:0034976 | 227 | 90 | 18204 | 5365 |
TRAF2,BAK1,NCK1,SELENOK,ERLEC1,PDIA3,VAPB,DDRGK1,RNF103,TMUB2,CALR,TMUB1,SGF29,RNF5,FAM8A1,AGR2,ATF3,PDIA2,SELENOS,UBXN6,CREB3,UBE2G2,STUB1,DNAJC10,ELAVL4,TMBIM6,SDF2L1,DERL2,AIFM1,KCNJ8,EIF2S1,SYVN1,CDK5RAP3,CASP4,DERL1,EDEM1,MIR200C,OS9,PML,HSP90B1,RPAP2,EDEM2,CCND1,UBXN10,UFM1,DNAJB9,NRBF2,XBP1,CFTR,CREBZF,SEC61B,ERO1A,EIF2AK2,BAX,FAF2,CXCL8,TMEM117,ERLIN2,RNF121,TP53,DDIT3,FLOT1,ATF4,JUN,PPP2CB,TMEM33,SCAMP5,PTPN1,ERLIN1,FAF1,EDEM3,PDIA6,NFE2L2,RNF139,UFL1,HM13,DNAJC3,EIF2B5,FBXO44,SGTA,GORASP2,DNAJB2,JKAMP,PIK3R2,HSPA5,PIK3R1,UFD1,CCDC47,MAN1A2,SESN2 |
| 6.171e-04 | -7.39 | MARCHF2 (membrane associated ring-CH-type finger 2) | protein interactions | 51257 | 76 | 35 | 19454 | 5460 |
F11R,SYNE4,STX6,TSPO2,VAMP7,WDR6,SSMEM1,RMDN3,S100A8,IKBKB,UBE2D1,TMEM106C,FIS1,UBE2H,TMEM179B,CTSD,SLC25A46,MARCHF5,SCN3B,FATE1,NDUFS2,ADRB2,FKBP8,BAP1,EXD2,DLG1,CHPF2,MTX2,NOTCH2,MTCH2,OTULINL,DDX39A,HADH,LGR4,CFTR |
| 6.171e-04 | -7.39 | CYP1A1 (cytochrome P450 family 1 subfamily A member 1) | protein interactions | 1543 | 76 | 35 | 19454 | 5460 |
CSTF3,NUP35,SNX3,SNX2,CAB39,EIF2S2,CYB5A,RPRD1A,EIF2AK2,CYB5R3,ZMPSTE24,CHORDC1,MMUT,NAA50,TBCE,PTPN11,GSTK1,PYGB,GTF2I,CTNNBL1,VRK1,TCEA1,EMG1,NSDHL,PSME1,UBE2M,DTD1,PICALM,ETF1,HPCAL1,EIF3J,RBM12,SF3A1,NAA15,PPP1R8 |
| 6.219e-04 | -7.38 | CYP2C9 (cytochrome P450 family 2 subfamily C member 9) | protein interactions | 1559 | 104 | 45 | 19454 | 5460 |
VEZT,TMEM199,RAB3D,TOMM40,PSMD1,DDRGK1,HMOX2,POR,ESYT1,ARFGAP3,CYP2D6,ZMPSTE24,SRPRA,PTPN1,CAMLG,STX5,STAT5A,DNAJC1,PSMD4,LMAN1,SEC63,PREB,RABL3,CCDC47,MACO1,STBD1,TOR1AIP2,SEC22B,PGRMC1,FAF2,RPN1,VAPB,STIM1,SLC12A2,STAMBP,PDCL,PSMC3,LEMD3,NSDHL,STX18,CYP2C18,HUWE1,YKT6,SRPRB,SSR3 |
| 6.219e-04 | -7.38 | CCDC124 (coiled-coil domain containing 124) | protein interactions | 115098 | 104 | 45 | 19454 | 5460 |
RAF1,TBK1,MAP1LC3B,SRP72,RPS11,EMC2,CASTOR2,ABCE1,EWSR1,TRIM26,SSRP1,MEPCE,WWP2,MAP3K14,XPO1,SNRNP70,DRG1,CAND1,RPS16,FZR1,RBM42,ATG16L1,HEXIM1,RPA3,PMAIP1,HSPA8,RPL4,G3BP2,AATF,USP14,H2BC9,DCAF4,H1-1,MAPRE1,EIF2AK2,METAP2,IRF2,PSPC1,SEC61B,PRKRA,GSK3A,RPL19,RPL10,DYRK1A,APEX1 |
| 6.227e-04 | -7.38 | CBFA_NFYB_domain | interpro domains | IPR003958 | 6 | 6 | 18521 | 5414 |
CHRAC1,POLE3,DR1,NFYB,DRAP1,POLE4 |
| 6.242e-04 | -7.38 | MRPL32 (mitochondrial ribosomal protein L32) | protein interactions | 64983 | 127 | 53 | 19454 | 5460 |
MRPS26,MRPL18,HNRNPA1,MRPL9,TRA2A,STOML2,RPL6,MALSU1,MRPL50,PRR3,GATD3,CETN3,MRPS9,MRPL51,RPL18,RAF1,MRPL11,MRPL47,SRSF4,MEPCE,RPL17,HNRNPDL,RPL23A,RPL3,SRSF7,MRPL52,SCFD1,RPL26,MRPL16,AUH,MYC,PMPCA,RPL19,MRPL23,RPL35,RPL13A,TUBB,MRPS28,MRPL13,MRPL53,ZNF574,MTRES1,MRPS18A,TMEM115,MRPL10,MRPL12,RBMS2,RPL27A,MPV17,MRPL40,MRPL57,MRPL41,NGRN |
| 6.253e-04 | -7.38 | response to growth factor | biological process | GO:0070848 | 525 | 189 | 18204 | 5365 |
DDIT4,SMAD4,PDE8A,WNT7A,COL3A1,SOX2,ITGB5,VSTM2A,SPINT2,ELAVL4,GCLC,TGFB3,NDNF,AKT1,HYAL2,CTSK,MAP1B,NPR2,FGF10,CTNNB1,ACTA2,NOTCH2,TGFB2,DUSP3,MAP2K3,TGFBR2,FMOD,PAK2,MIR130A,SNAI2,BECN1,CRKL,CHST11,GRIA1,MIR20A,CBL,FLRT3,SOX9,SHC1,RGMA,SMAD1,RGMB,GAD2,CAV2,NRP1,MIR339,FGF1,USP15,EEF1A1,SMAD5,VEGFC,JUN,PDCD5,ID1,INPP5K,CREB1,NDST1,IGF1R,SFRP1,FLCN,FERMT2,CSNK1E,MYC,MARS1,MIR142,HSPB1,BGLAP,TMEM100,ACVR1C,CCL5,KCNC1,DLX1,UBE3A,CLDN1,MSX2,EHD4,MIR149,DTYMK,FGFBP1,MIR30B,MIR21,SMURF1,TNFRSF1B,HTRA2,SMAD2,ZYX,MSTN,ARPC3,NUS1,MEF2C,CAV1,PAX6,ELK1,USP8,FURIN,DSTYK,TAB1,HDAC6,ITGB8,NOG,CHRDL1,MIR23A,FGF7,FGF16,RAB14,HFE,EPHA2,ACVR1B,RAP1A,EIF4A3,CX3CR1,MSX1,TMEM108,COL1A2,WNT2,YES1,FGF17,TWSG1,FGF3,XCL1,ROCK2,IL10,DUSP22,RAF1,SMAD3,MIR1298,FRS3,FUT8,ARF6,RAB35,FEZ1,CD2AP,NDP,ACVR1,MIR183,EID2,CITED1,CCL2,DUSP6,FOS,BMPR1B,PDE2A,PML,SOSTDC1,NDN,PTPN11,PAX9,KLF4,FASLG,DDIT3,TLR4,EXT1,P2RY1,FGFR1,SRC,FGF22,SOST,STK16,PDCD4,ROCK1,EHD1,DDX5,CXCL8,MDM2,PIK3CA,TAC1,FKBP8,NTF4,TP53,MIR212,PPARG,NTRK2,FLRT2,STMN2,NTRK3,CXCL13,MIR30A,SHOC2,CCNA2,ACAP2,GAB1,VEGFA,BMPR2,IER2,LPXN,SMAD9,FGF23,BMPR1A,EGR1 |
| 6.310e-04 | -7.37 | palmitoyl-(protein) hydrolase activity | molecular function | GO:0008474 | 13 | 10 | 18094 | 5411 |
ABHD10,DESI2,LYPLA2,PPT1,ABHD12,ABHD13,DESI1,LYPLA1,LYPLAL1,ABHD17A |
| 6.310e-04 | -7.37 | molecular tag activity | molecular function | GO:0141047 | 13 | 10 | 18094 | 5411 |
UBL5,ISG15,URM1,UBA52,RPS27A,SUMO2,SUMO3,NEDD8,UBB,SUMO1 |
| 6.310e-04 | -7.37 | protein tag activity | molecular function | GO:0031386 | 13 | 10 | 18094 | 5411 |
SUMO1,NEDD8,SUMO3,UBB,SUMO2,RPS27A,UBA52,URM1,ISG15,UBL5 |
| 6.323e-04 | -7.37 | NAT10 (N-acetyltransferase 10) | protein interactions | 55226 | 287 | 106 | 19454 | 5460 |
RNF113A,RPA3,THUMPD1,SIRT7,PML,AATF,DGCR8,NPM3,HMGB1,RPL4,FBXW7,CDK7,FGF13,RPS14,ZNF574,RPL26L1,RPLP0,HECTD1,RPA2,USE1,FGFBP1,UBE2I,RPS3,EIF2AK2,ZNF330,SRPK2,VIRMA,YES1,RPL13A,MECP2,ABCE1,RPL23A,RPL3,RIGI,RPL17,H3C1,IMP4,CD2BP2,AURKAIP1,TP53,RPSA,NUPR1,SYNCRIP,KRR1,MDM2,SURF6,CDC5L,ZBTB2,FZR1,CAND1,TOP1,HDAC6,ZMYND11,DPP4,RPS2,NOL12,BRD3,CHCHD1,TERT,EP300,STAU1,MTF1,PPARG,APOBEC3C,MAP2K1,APEX1,RPL19,RPL10,RPL35,ZNF668,MYC,RAB11A,CUL3,RPS5,CDKL2,H1-1,RIT1,FBXW11,BRCA1,LMNB1,RPS24,RPL31,MORC2,SRSF4,TFG,H1-6,KRAS,LASP1,ISG15,SOX2,RAF1,RPS11,CHMP4C,EED,SELENOM,SRSF1,HNRNPL,RPS10,NOP58,LYAR,SUMO2,NGDN,DDRGK1,IFI16,WWP2,DDX23 |
| 6.328e-04 | -7.37 | AKIRIN1 (akirin 1) | protein interactions | 79647 | 20 | 13 | 19454 | 5460 |
PSMB9,SEC13,PSMB3,CSNK1A1,RNF181,PSMB7,PSMA6,RAN,ZBTB2,HNRNPL,PSMA5,PSMA2,HNRNPF |
| 6.328e-04 | -7.37 | MLC1 (modulator of VRAC current 1) | protein interactions | 23209 | 20 | 13 | 19454 | 5460 |
VAMP3,YTHDF1,SPPL3,KDM1A,MDC1,CAV1,ROCK1,PRMT6,TPT1,MZT2B,FGFR1,KCNJ10,SNTA1 |
| 6.328e-04 | -7.37 | RFX7 (regulatory factor X7) | protein interactions | 64864 | 20 | 13 | 19454 | 5460 |
YWHAH,RFXANK,YWHAG,DYRK1B,YWHAB,KLF3,GSK3A,RFX5,HAPSTR1,POLR3H,ANKRA2,VIRMA,DYRK1A |
| 6.328e-04 | -7.37 | GLIPR1L2 (GLIPR1 like 2) | protein interactions | 144321 | 20 | 13 | 19454 | 5460 |
SQSTM1,MKLN1,SNX11,MAEA,TMEM160,GID4,RANBP10,CNTNAP1,ZMYND19,SYNJ2BP,TOMM22,PROS1,ARMC8 |
| 6.328e-04 | -7.37 | Hsph1 (heat shock 105kDa/110kDa protein 1) | protein interactions | 15505 | 20 | 13 | 19454 | 5460 |
TCP11L1,BCL2L1,XPOT,BAZ1B,ANO3,CFTR,BUB3,SNRPG,TUSC2,ATP5MK,CCNF,SOD1,DNAJB4 |
| 6.328e-04 | -7.37 | STAC2 (SH3 and cysteine rich domain 2) | protein interactions | 342667 | 20 | 13 | 19454 | 5460 |
LMNA,BRCA1,EIF1AX,SNX5,RBM12,URM1,F11R,SNX1,ADO,MDC1,ATXN1L,METAP2,RB1 |
| 6.340e-04 | -7.36 | mRNA Capping | REACTOME pathways | R-HSA-72086 | 29 | 18 | 10285 | 3229 |
POLR2F,CCNH,POLR2C,POLR2G,GTF2H4,GTF2F2,GTF2F1,GTF2H2,POLR2D,GTF2H5,POLR2I,POLR2L,CDK7,MNAT1,ERCC3,SUPT5H,POLR2B,NCBP2 |
| 6.370e-04 | -7.36 | ribonucleoprotein complex binding | molecular function | GO:0043021 | 170 | 71 | 18094 | 5411 |
SRPRA,SEC61A2,USP16,TOP2B,MTRES1,ZNF622,IFIH1,IMPACT,RPLP1,PYM1,PIWIL2,PQBP1,RPSA,XPO5,ETF1,CD2BP2,TMA16,PRMT5,WDR12,SEC61A1,LEMD3,OLA1,RNASEL,CPEB1,DDX5,IFRD2,EIF3K,NOPCHAP1,EIF1B,UHMK1,SEC61B,SNRPB,NAA15,RBM3,CCDC47,NAA16,ZNF593,SNRPD3,YTHDF1,MAIP1,NME1,RBM23,DNAJC2,DERL2,SNRPA,PPIH,MDM2,SRP54,ABCE1,EZH2,DERL1,CINP,EEF2,MALSU1,PELO,TACO1,SECISBP2L,SRP72,PRPF31,HSPA5,PIWIL1,G3BP1,DHX9,NDUFAB1,TMEM147,CBX5,EIF2S1,EIF4A3,SEC61G,EIF5A2,SNRPN |
| 6.388e-04 | -7.36 | NAD2 | pfam domains | PF18782 | 6 | 6 | 17795 | 5224 |
APOBEC3F,APOBEC3G,APOBEC3B,APOBEC3A,APOBEC3D,APOBEC3C |
| 6.388e-04 | -7.36 | CBFD_NFYB_HMF | pfam domains | PF00808 | 6 | 6 | 17795 | 5224 |
DR1,POLE4,DRAP1,POLE3,CHRAC1,NFYB |
| 6.421e-04 | -7.35 | pigment granule | cellular component | GO:0048770 | 112 | 49 | 19108 | 5553 |
CAPG,SEC22B,PRDX1,CTSD,CNP,TMEM33,PDIA3,MREG,SYNGR1,CALU,MMP14,RPN1,GANAB,ATP1B3,FLOT1,ATP1A1,SLC2A1,RAB27A,GCHFR,STOM,PDIA6,HSP90B1,CD63,CTSB,GGH,YWHAZ,SDCBP,RAB9A,RAB35,TFRC,ATP6V1G2,PPIB,RAB5C,HSP90AA1,HSP90AB1,RAB32,RAB2A,RAN,GPNMB,ERP29,RAB1A,RAB29,RAB5A,YWHAB,DNAJC5,SYPL1,HSPA5,NCSTN,HSPA8 |
| 6.421e-04 | -7.35 | melanosome | cellular component | GO:0042470 | 112 | 49 | 19108 | 5553 |
RAB27A,GCHFR,SLC2A1,FLOT1,ATP1A1,CTSB,GGH,CD63,HSP90B1,STOM,PDIA6,CTSD,CNP,TMEM33,SEC22B,PRDX1,CAPG,ATP1B3,GANAB,RPN1,MREG,PDIA3,SYNGR1,CALU,MMP14,RAB1A,GPNMB,ERP29,RAB2A,RAN,RAB32,NCSTN,HSPA8,YWHAB,SYPL1,DNAJC5,HSPA5,RAB29,RAB5A,RAB35,TFRC,ATP6V1G2,SDCBP,RAB9A,YWHAZ,HSP90AB1,HSP90AA1,RAB5C,PPIB |
| 6.453e-04 | -7.35 | inner mitochondrial membrane organization | biological process | GO:0007007 | 40 | 22 | 18204 | 5365 |
SLC25A46,TIMM8A,APOO,MTX2,AGK,CHCHD6,GHITM,CHCHD3,TOMM70,TIMM10,TRMT10B,BCS1L,TIMM29,MAIP1,CIBAR1,ROMO1,UQCC3,SAMM50,TMEM11,TIMM8B,TIMM13,TAFAZZIN |
| 6.499e-04 | -7.34 | PRORP (protein only RNase P catalytic subunit) | protein interactions | 9692 | 133 | 55 | 19454 | 5460 |
POU5F1,MRPS26,RHOG,CBR4,PFDN5,GRSF1,MTRF1,RMND1,MALSU1,PRNP,RHOH,HNRNPL,GATD3,RAC2,FAHD1,YBEY,SSBP1,CYB5B,PDHA1,METTL15,IL1R2,MRPL11,IMMP2L,MRPS17,RASL10B,SEMA4C,KRAS,COX8A,MRPS18B,EFNB1,SLC25A10,RIT1,NTRK3,PYCR1,AUH,ESR2,RHOJ,CCDC90B,TACO1,CCNF,SCN2B,MTRES1,LMNA,KLRD1,MRPL12,FAXC,RND2,RP2,SLC31A1,HSCB,GFM1,AMACR,EXD2,NGRN,RHOU |
| 6.500e-04 | -7.34 | positive regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050731 | 161 | 67 | 18204 | 5365 |
IL4,ACVR1,KIT,OSM,CD4,HBEGF,DLG3,PAK2,MIR221,EHD4,IL2,ARL2BP,CLEC6A,IL34,NRP1,IL5,TNFRSF14,EPO,JAK2,HCLS1,IL15,FCGR1A,ADNP,EFNA5,IL3,IL23A,CD80,VEGFA,CD36,HTR2A,PTPN1,SRC,IL12A,GHR,ANGPT1,CD40,SYK,FGF7,IL18,MIF,CSH1,TNFSF18,GREM1,DLG4,LEP,HAX1,FBXW7,CSF2,IL6ST,PRNP,PTPN11,EPHA4,IL12B,TP53,IFNG,OSBP,IGF1,TNF,CCL5,ADIPOQ,IL13,YES1,LACRT,GH1,FGF10,IL6,IL21 |
| 6.505e-04 | -7.34 | DCAF4 (DDB1 and CUL4 associated factor 4) | protein interactions | 26094 | 378 | 135 | 19454 | 5460 |
RPL7A,CEP85,CTSD,HYCC2,ATP5F1A,RPL26,RC3H2,DCAF16,IGF2BP1,CCSER2,OPTN,RPS3,CTU1,UBASH3B,PRKRA,RPL13A,ZNF622,TXN,WDR5B,RBFOX2,RBMS2,ST7,HSP90B1,ZNF326,ACACA,LUC7L3,HNRNPH3,KRT7,AMACR,SOD1,SYVN1,HMGB1,MARS1,LRRTM2,SPATS2L,MOV10,GRSF1,APOBEC3F,GAPDH,NR2F6,COPS5,MPHOSPH10,SMAD3,SYNCRIP,AIP,HACD3,SEC23A,SURF6,DKC1,IPO8,TNRC6C,YTHDF2,CCT5,CAPZA2,ZDHHC8,LLPH,SERPINA1,MSRB3,NKRF,TCOF1,HSD17B10,PC,RPL3,TTC4,BACH1,COPS7A,PCCB,DCAF4,WDR20,CCT2,DNAJB6,H1-1,PFDN6,PFDN2,POLR2F,ZCCHC7,LAP3,ARMCX3,AP5M1,FDFT1,TRMT112,WNT2,CCDC9B,EP300,DDX5,TXNL1,STAU1,PHB2,YTHDF1,SKP1,FTL,PFDN5,DYRK1B,PDIA3,CTNNB1,EIF3D,FKBP4,DCAF5,RPL23,CDKN1B,FUBP3,SIN3A,COPS2,SPINT2,S100A8,TCP1,NOP58,NOB1,COPS7B,HSP90AB1,CCT7,SRSF10,TOP3B,TNPO2,RPL18,CSTPP1,LSM14A,CCT8,TOP2B,HSPD1,S100B,TRIP4,PDIA6,SRSF7,EWSR1,VDAC1,RBBP7,TRIM26,HNRNPDL,COPS4,SSRP1,SERPIND1,IFNG,PFDN1,SECISBP2L |
| 6.515e-04 | -7.34 | negative regulation of kinase activity | biological process | GO:0033673 | 181 | 74 | 18204 | 5365 |
PPP2R5A,GADD45A,CAMK2N2,MIR711,CBL,PKIG,SOCS5,CDKN1B,GSKIP,MIR20A,SLC8A1,TRIB1,LILRB4,PAQR3,MIR218-1,SFN,PAK2,PPARG,PKIB,MACROH2A1,LRP6,CDKN1A,CAV1,TSG101,PTEN,CEP85,DEFB114,CAV3,UBASH3B,RB1,TESK1,CDK5RAP3,AKT1,PTPN1,INPP5K,IL1B,RGS2,HEXIM2,ERRFI1,CORO1C,PTPRQ,PTPN22,THY1,PYCARD,PKIA,STK38,DUSP10,TRIM27,SOCS4,HEXIM1,SPRY1,CHP1,MIR24-1,DUSP3,IFNG,DUSP22,CAMK2N1,DBNDD1,SPRED1,ADIPOQ,YWHAG,TAF7,GNAQ,MIR34A,PPIA,MIR15A,DUSP19,PRDX3,HSPB1,DUSP1,PDCD4,GSTP1,HYAL2,RTRAF |
| 6.526e-04 | -7.33 | receptor internalization | biological process | GO:0031623 | 73 | 35 | 18204 | 5365 |
AP2A1,PICALM,CACNG3,CD9,CD81,LILRB4,SNAP25,LMBRD1,DRD3,GTF2H2,DNM2,SYK,ACKR3,SNX1,GRIA1,CALY,RAB5A,RALB,LILRB1,CXCR1,RAMP3,CD36,HGS,RAB31,RALA,CAV3,TFRC,AP2M1,ACHE,CAV1,LRRTM1,CXCL8,AP2S1,SCYL2,FCER1G |
| 6.526e-04 | -7.33 | regulation of transcription initiation by RNA polymerase II | biological process | GO:0060260 | 73 | 35 | 18204 | 5365 |
MED31,NFKBIA,MED4,MED29,TAF11,TAF7,TAF10,CAND1,MED17,TP53,WNT10B,TAF9,ZNF451,MYC,NFKB1,MED9,MED27,MED23,GTF2A1,MDC1,HMGB1,PPM1D,HNF1B,SUB1,MED10,TAF2,MED30,ZNHIT1,MED11,HEY2,MED21,CTNNBIP1,MED22,GTF2A2,CDK4 |
| 6.526e-04 | -7.33 | Mitophagy - animal | KEGG pathways | ko04137 | 64 | 35 | 7161 | 2463 |
GABARAPL1,MRAS,USP15,CSNK2B,RRAS2,ATG9A,FUNDC1,TBK1,BNIP3L,TFEB,GABARAP,UBB,MITF,CSNK2A1,GABARAPL2,USP30,FIS1,JUN,BECN1,TOMM7,TFE3,ATF4,BCL2L1,MAPK10,TBC1D17,SQSTM1,OPTN,SRC,USP8,HRAS,SP1,TP53,MFN1,KRAS,TAX1BP1 |
| 6.526e-04 | -7.33 | Mitophagy - animal | KEGG pathways | hsa04137 | 64 | 35 | 7161 | 2463 |
HRAS,USP8,SRC,SP1,OPTN,TBC1D17,SQSTM1,TFE3,BECN1,TOMM7,BCL2L1,MAPK10,ATF4,KRAS,TAX1BP1,MFN1,TP53,USP15,CSNK2B,RRAS2,MRAS,GABARAPL1,FIS1,JUN,USP30,CSNK2A1,MITF,GABARAPL2,TFEB,UBB,GABARAP,FUNDC1,ATG9A,TBK1,BNIP3L |
| 6.532e-04 | -7.33 | Neutrophil degranulation | REACTOME pathways | R-HSA-6798695 | 487 | 186 | 10285 | 3229 |
CTSC,TYROBP,ORMDL3,B2M,OLR1,S100A8,CXCL1,TTR,GSTP1,DEGS1,PSMD3,LILRA3,PLAC8,PSMB7,LAMP2,DNAJC3,AP1M1,PGRMC1,HSPA8,TMBIM1,ATP6AP2,PSMD7,FGL2,NCSTN,BRI3,SERPINB1,DSN1,RAP1A,TOM1,CMTM6,ENPP4,MME,HEXB,RAB5C,EEF1A1,RAB3D,LAMTOR1,RETN,PGAM1,FCAR,CTSA,CAB39,NEU1,HEBP2,RAB31,CXCR1,CD47,S100A11,PSMD6,DNAJC5,RAB37,GGH,SIGLEC5,CCT2,PSMA5,FCER1G,RHOG,CYB5R3,SLPI,RAB3A,SNAP25,FABP5,ATG7,PADI2,CTSB,ARMC8,PNP,RAP1B,PPIA,SRP14,COMMD3,TMEM30A,RAB9B,SNAP29,TNFAIP6,LAMTOR2,PYGB,CHI3L1,RAP2C,CAPN1,HP,GDI2,EEF2,PDAP1,COTL1,PRCP,APEH,PRDX4,TOLLIP,PSMC3,PGM1,RAB18,B4GALT1,SYNGR1,ATP6V1D,CPNE1,CD14,HMGB1,RAB6A,GCA,TICAM2,CST3,PSMA2,TMT1A,COMMD9,CAMP,RAP2B,TNFRSF1B,PSMB1,CSNK2B,SNAP23,MIF,SERPINA1,CALML5,PSEN1,RAB27A,PSMD14,ILF2,SERPINB6,HBB,CCT8,PYCARD,PSMD12,CAND1,BST2,XRCC5,FTL,RNASET2,TRAPPC1,ATP8A1,GOLGA7,FAF2,JUP,CD63,DYNLL1,SPTAN1,SERPINB10,ACTR2,SERPINA3,NFKB1,HUWE1,CYSTM1,SELL,FCGR2A,HSP90AB1,STBD1,DNASE1L1,NPC2,NDUFC2,VAMP8,PLEKHO2,CD58,RAB14,SVIP,HMOX2,ROCK1,MMP9,FTH1,LGALS3,SDCBP,FGR,NME2,CD36,HSP90AA1,PSMD1,TUBB,GLIPR1,SURF4,YPEL5,PAFAH1B2,CD59,PRDX6,ACTR1B,AGA,SLC2A3,CTSD,TMEM179B,LAMTOR3,CSTB,ITGAV,TUBB4B,TBC1D10C,STOM,IDH1,LYZ,TLR2 |
| 6.534e-04 | -7.33 | ITCH (itchy E3 ubiquitin protein ligase) | protein interactions | 83737 | 309 | 113 | 19454 | 5460 |
SMAD4,BECN1,CSNK2A1,HDAC6,MDM2,CAV1,RNF128,RAC2,CD274,SMAD3,RCHY1,SH3GLB1,GRAP2,DISC1,ESS2,RPAP2,TP53,PDE2A,RIGI,SMN1,WASL,LRP3,TOLLIP,KPNA2,KLF10,ILDR1,MARCHF3,SMAD2,TMEM255A,LRP6,SPOP,TXNIP,UBE2E3,GEMIN8,DNAJC5,TNFAIP3,UBE2L3,GNAI2,VIRMA,JUNB,RHOJ,OPTN,UBE2M,RPA2,WWP1,CDC42,MYCT1,CFTR,PDCD1LG2,UBE2K,LITAF,PRRG1,MAVS,RAB9A,DVL2,RHOU,RPA3,POU5F1,CBL,RHOG,UBE2D1,IKBKB,TRAF6,YWHAG,UBE2E2,WWP2,STK3,HNRNPL,SNX18,RHOH,GJA1,PHB1,POLR2C,HGS,SOX2,JUN,RAF1,NFE2,KRAS,PCNA,EWSR1,RPAP3,LDLRAD4,PABPC1,BAX,LAMTOR1,CGRRF1,RHOB,SMARCE1,MYC,USP13,CUL3,SFN,POLR2B,USP5,TAB1,NDFIP1,TAX1BP1,LMBR1L,PIP4P2,MAP2K1,RND2,FBXO42,ZC3H14,SUFU,RNF11,TGFB1I1,UBE2D3,ADRB2,HSPA8,ARRDC3,CXCR4,WBP2 |
| 6.538e-04 | -7.33 | SHROOM3 (shroom family member 3) | protein interactions | 57619 | 68 | 32 | 19454 | 5460 |
CFTR,TUBA1A,TOP3B,ATG16L1,HECTD1,ZYX,DDX39B,SAR1B,RNF11,CTNNB1,YWHAH,BTF3,YWHAG,SFN,RAB32,MYC,ILK,YWHAB,ZDHHC15,RHOB,MYO6,PSMD14,YWHAZ,PTEN,SEC61B,ARL10,ESR2,VIRMA,CDC5L,UBTD1,DYNLL1,HNRNPL |
| 6.538e-04 | -7.33 | CAB39 (calcium binding protein 39) | protein interactions | 51719 | 68 | 32 | 19454 | 5460 |
STRADB,CRYZ,VPS26B,IDH1,BCKDK,RPA3,RPA2,CDK7,GTF2E2,TIMM13,OTULINL,EBLN2,TP53,INSIG2,COMTD1,UBL5,ZBTB2,FAHD1,G6PC3,MOB4,UBE2N,SIN3A,TACO1,STK11,PDCD10,CYP1A1,STK24,PIP4K2C,TOMM40,MCCD1,CUL2,TM4SF20 |
| 6.538e-04 | -7.33 | GJB5 (gap junction protein beta 5) | protein interactions | 2709 | 68 | 32 | 19454 | 5460 |
TSPO2,TMEM97,ALB,RPRM,COMT,LYZ,LACRT,SCGB1D1,SLC41A1,PLPP4,SLC38A7,AZGP1,CLU,PLPP6,TMEM60,TF,ERG28,LCN1,PCGF2,JAGN1,LRP10,JCHAIN,SERPINA1,FAM3C,CYB5B,BPIFB1,LMNA,SEC22A,SERPINA3,CTXN3,SEC22B,PGAP2 |
| 6.538e-04 | -7.33 | OTUD7B (OTU deubiquitinase 7B) | protein interactions | 56957 | 68 | 32 | 19454 | 5460 |
TAX1BP1,PRNP,FZR1,VIRMA,UBB,CDC20,UBE2S,CCNF,PSMB1,BECN1,TRAF6,CDIP1,CUL3,WWP2,PIK3R3,CCNB1,MYC,CTNNB1,MAP3K14,XPO1,KDM1A,ZDHHC17,IRF3,SQSTM1,IGF1R,FAM168A,MAVS,OTULIN,TANK,LGR4,AGO1,SOX2 |
| 6.538e-04 | -7.33 | POLH (DNA polymerase eta) | protein interactions | 5429 | 68 | 32 | 19454 | 5460 |
UBE2B,SART3,LGR4,HYAL2,RBBP7,DHX16,PIAS1,RPS27A,PACSIN3,DVL2,WBP2,SIRT7,POLD2,PCNA,H2AC4,DCAF4,BRCA1,COP1,HSP90AA1,GTPBP2,MYC,HNF1B,AR,SNRNP40,ACTB,LSM5,DYNLL1,TUBB,MDM2,TUBA1B,RCHY1,PHF21A |
| 6.538e-04 | -7.33 | TDP2 (tyrosyl-DNA phosphodiesterase 2) | protein interactions | 51567 | 68 | 32 | 19454 | 5460 |
MYC,RAB11A,EPS8,TRAF6,COP1,SMAD3,TNFRSF1B,AZIN1,UBE2I,TCEAL1,SUMO3,SPMIP5,SUMO2,NAA11,SRPK2,SUMO1,TP53,TRAF2,LMNA,RNF7,TFIP11,RNF181,DVL2,CD40,WBP2,PML,RAP2A,ZBED1,H3C1,STAU1,PSEN1,COIL |
| 6.540e-04 | -7.33 | clearance of foreign intracellular DNA | biological process | GO:0044355 | 6 | 6 | 18204 | 5365 |
APOBEC3F,APOBEC3A,APOBEC3C,APOBEC3H,APOBEC3D,APOBEC3B |
| 6.540e-04 | -7.33 | cytoplasmic sequestering of NF-kappaB | biological process | GO:0007253 | 6 | 6 | 18204 | 5365 |
G3BP2,IL10,FAF1,CCDC22,NFKBIA,PSMD10 |
| 6.540e-04 | -7.33 | clearance of foreign intracellular nucleic acids | biological process | GO:0099046 | 6 | 6 | 18204 | 5365 |
APOBEC3H,APOBEC3D,APOBEC3B,APOBEC3F,APOBEC3C,APOBEC3A |
| 6.540e-04 | -7.33 | negative regulation of bicellular tight junction assembly | biological process | GO:1903347 | 6 | 6 | 18204 | 5365 |
ROCK1,MIR105-1,IKBKB,ROCK2,TNF,MIR142 |
| 6.549e-04 | -7.33 | CCDC97 (coiled-coil domain containing 97) | protein interactions | 90324 | 52 | 26 | 19454 | 5460 |
SF3B5,SNRPE,LBH,JUN,SF3A1,PIP5K1A,SF3B1,COMMD2,SKIC8,FAS,H2AC4,DNAJC8,TTC33,SNRPB,ATF1,MOV10,SRPK2,SNRPB2,CDC5L,DYRK1A,COMMD6,SNRPA1,SNRPD2,SF3B4,SNRPD1,SF3B6 |
| 6.549e-04 | -7.33 | DNAJB3 (DnaJ heat shock protein family (Hsp40) member B3) | protein interactions | 414061 | 52 | 26 | 19454 | 5460 |
UTP6,BAG3,PCBD1,TRAF3IP2,HNRNPA1,TBCE,DNAJC7,NXT1,CCNF,AIP,HYPK,DYNC1I2,GPX1,SOX2,PGRMC1,TMEM231,VPS26B,C1D,HSPA8,EWSR1,ARGLU1,BAP1,COPS4,GINS3,GRPEL1,UFL1 |
| 6.613e-04 | -7.32 | TRIM13 (tripartite motif containing 13) | protein interactions | 10206 | 136 | 56 | 19454 | 5460 |
CYP2C9,TMT1A,IGF1R,KRAS,RAB3B,FKBP8,DNAJC25,PPIF,RPN1,STIM1,RAB4A,KCNF1,RAB35,PTPN1,HSD17B11,GJA1,COPS2,MARCHF4,DNAJC1,AASDHPPT,RHOH,TMPO,MDM2,LMAN1,SLC25A46,LAMP3,TMBIM6,RHOG,BECN1,ESYT1,TRAF6,VPS4A,SYVN1,SQSTM1,RAB9A,DERL1,RAB5A,STX7,PXMP2,DNAJC22,MTX2,CDC42,SEC62,OTULINL,ST7,PPARG,FGFR1,SSR1,IDH2,RMDN3,SEC61B,SEC63,AKT1,RAB11A,HMOX2,ABCG2 |
| 6.618e-04 | -7.32 | TAF6 (TATA-box binding protein associated factor 6) | protein interactions | 6878 | 238 | 90 | 19454 | 5460 |
HSPB1,CDC26,ZCCHC10,TAF7,SNRPD3,DYNC1I2,SIN3A,CORO1C,TUBB4B,TAF10,MTA2,SMARCB1,SUPT5H,MARCKSL1,MAX,ELF1,SAP30,RPL29,RUVBL1,RBBP7,KRAS,PAX6,AHCYL1,RUVBL2,RABGGTB,H2AZ2,ATG3,MYO6,SETD7,RIT1,NFYA,MCM3,HMGCS1,RBBP4,TSN,PSMD4,STAT1,TAF11,BTG3,GNB1,ELK3,DLST,RAN,GTF2F1,MYL6,ACTL6A,EEF1G,RFC4,EP300,TXNL1,H2AC4,BRD3,TAF9,TPM3,GTF2E1,DKC1,POLE3,MYL12A,TAF2,TP53,SMAD1,CSE1L,TTC4,H3C1,PSMA5,SMAD2,XPOT,NAPA,SMARCA5,CHMP5,MOB4,PHAX,GTF2A1,RPA2,DYRK2,NFYB,ATG16L1,FTH1,CCNA2,CDK7,KLF12,KDM1A,MBD3,PML,PRPF4,RPA3,DDX46,RNF113A,TCEA1,SPATA25 |
| 6.618e-04 | -7.32 | LCOR (ligand dependent nuclear receptor corepressor) | protein interactions | 84458 | 238 | 90 | 19454 | 5460 |
CCT2,SAMHD1,RPL39,LDB1,RPF1,RBBP4,ACTB,ATP5F1B,GNB1,APEX1,B4GAT1,RORB,IFT172,PPT1,CTBP1,GAMT,NDE1,STAU1,ASB3,FBXW4,NUP50,DENND6B,STAMBPL1,LRRC4,HMGA1,CNOT2,HNRNPL,LRWD1,PSMB4,CEP57L1,EED,EZH2,RBPJ,VDR,EEF2,NUP42,ASF1A,RBBP7,GUK1,COPS4,HNRNPDL,ABCF1,BCL7B,GDAP1L1,EWSR1,OAT,CYRIA,CNTNAP1,CEP70,AR,CHPF,CTSB,VIRMA,TRAF1,TFEB,DEK,EZH1,ZNF330,GSK3A,SDCBP,ARHGAP1,SMYD3,CREBZF,NUCKS1,HDAC3,CLU,GLIPR1,EPOP,DNAJC7,HDAC6,COPS5,PRNP,NOP9,AIP,CBX3,ALPL,CCT5,SRFBP1,UBR7,NDST1,TF,H3C1,DYNC1I1,MDC1,GALNT2,PHF1,VWF,GLUL,PC,STX18 |
| 6.627e-04 | -7.32 | response to unfolded protein | biological process | GO:0006986 | 119 | 52 | 18204 | 5365 |
DDIT3,SELENOS,CREB3,ATF4,TOR1B,DNAJC4,HSP90AA1,ATF3,TMBIM6,HSPA8,SERPINH1,PTPN1,HSPD1,DERL2,STUB1,DNAJC10,TRAM1,ERLEC1,HSPB1,CREB3L4,FAF2,HSPB2,KBTBD6,BAK1,BAX,VAPB,DNAJC3,HSPE1,DNAJB2,DNAJB9,JKAMP,HSPB8,EDEM2,PACRG,CCND1,BAG3,EIF2AK2,ERO1A,HSPA5,CREBZF,XBP1,DERL1,HSP90AB1,CDK5RAP3,EDEM3,OPTN,EIF2S1,OS9,RPAP2,EDEM1,NFE2L2,DNAJB4 |
| 6.627e-04 | -7.32 | negative regulation of cellular catabolic process | biological process | GO:0031330 | 119 | 52 | 18204 | 5365 |
AKT1,ADRA1A,PTPN22,TIMP4,MTMR2,RNF41,LEP,TRIM27,PIK3CG,RNF5,HDAC6,ETFBKMT,POLDIP2,TAB2,IL10,TP53,PIK3CA,RRAGA,EP300,USP30,NUPR1,LEPR,MT3,SEC22B,TIMP3,ROCK1,EIF4E,MCL1,STK38L,MET,KLHL22,TSPO,FEZ1,MTM1,CNR1,MIR21,SCFD1,SNRNP70,MIRLET7B,BECN1,FURIN,RRAGB,TMEM39A,WDR6,PHF23,CPTP,ATP2B4,LYPLA1,TIMP1,DAP,HP,CTSA |
| 6.638e-04 | -7.32 | STMN2 (stathmin 2) | protein interactions | 11075 | 79 | 36 | 19454 | 5460 |
IGBP1,DSTN,UBE2I,SEC23A,PSMB1,SESTD1,STUB1,COMMD6,VPS26C,GPRASP2,NTAQ1,COMMD5,CEP70,CCHCR1,COMMD9,CCDC22,COMMD2,PMAIP1,RGS6,PPM1G,PSMC1,MBD3,AHCYL1,EEF1A1,COMMD3,MAPK10,CDC42,RAF1,MTA3,ASRGL1,COMMD8,MTA2,ZER1,CDK1,TFCP2,TUBB4B |
| 6.638e-04 | -7.32 | KMT5A (lysine methyltransferase 5A) | protein interactions | 387893 | 79 | 36 | 19454 | 5460 |
H2AC13,H3C1,SKP1,HNRNPA2B1,PABPC1,RPL27,RPL31,RPL23A,PCNA,EZH2,RPA2,CSNK1A1,RNF8,RPL26L1,RPLP0,TP53,RPL15,PRNP,RPL7,RPL35,RBBP4,FZR1,RPL35A,RPL8,RPLP2,UBE2I,EED,RPL37A,S100A8,H1-10,RPL10A,DTL,HNRNPC,RPL7A,RPL6,HDAC6 |
| 6.638e-04 | -7.32 | EI24 (EI24 autophagy associated transmembrane protein) | protein interactions | 9538 | 79 | 36 | 19454 | 5460 |
STIM1,RPN1,SSR1,STOM,EMC9,GPR35,TMEM14B,ATP5PB,NUP62,CCDC47,YIPF5,OTULINL,YIPF3,SEC62,HSCB,KRAS,TMT1A,ATP5PF,TSPAN15,ATP5IF1,RABAC1,LPAR2,VIPR1,DERL1,RTN4,ATP1A3,P2RY1,SLC2A1,ATG3,LAMP2,RALB,RAB5C,EDEM1,ATG7,HSD17B11,SEC61B |
| 6.653e-04 | -7.32 | positive regulation of RNA metabolic process | biological process | GO:0051254 | 1912 | 625 | 18204 | 5365 |
PIM2,CD28,TADA1,CBFB,MEF2C,MSTN,RUVBL2,SUPT7L,ING2,MEPCE,GPBP1L1,IFNB1,TNKS,MAVS,ZBTB17,RC3H2,MEAF6,KANSL3,MIR149,ZGLP1,SNRNP70,CD4,DGCR8,CD81,NKRF,EGR2,PSEN1,MIR146A,MDC1,RBM22,IRF9,HSPA5,RUNX1,SMAD2,MIR342,MYD88,TAF2,TAF5L,BUD31,IL4,ALKBH5,SLC38A3,ILF2,BRCA1,MYC,CREB1,SFRP1,RTRAF,MIR142,MARS1,NUPR1,AGO1,MIR106B,RORB,CASK,MOSPD1,TLR3,PELP1,DLX1,WWP2,SSBP2,GTF2F2,SMAD5,RFX4,NFIL3,MAP3K12,HEY2,MED21,BARX2,IRF3,TNFSF8,SETD7,KLF12,YWHAH,PSRC1,HNF1B,MIR190B,BCL10,INPP5K,LILRB1,OSR2,RPS6KA4,APLN,MOV10,PAGR1,FOSL2,PRMT2,IRF8,SHC1,CTBP1,HDAC5,MAP2K1,PRKCB,COPS5,NUCKS1,ANKRD49,SETD3,SMAD1,RGMB,MIR200C,EDF1,IL5,BUD23,TLR7,IRF7,ZBED1,ACTN4,CDC5L,RIT2,PRPF19,MIR708,KDM1A,NR1I2,TOPORS,CDK7,MAFG,LITAF,PICALM,RBM23,SF3B5,CNOT6,TRIM22,HOXC4,NFE2,TADA3,CIRBP,MIR20A,SUB1,MTF1,BAZ1B,AIP,STAT2,SOX9,FGF10,RERE,TF,ZBTB38,TRIM8,NCK1,MIR9-1,SCAND1,IRF6,RPRD1B,RASL11A,NOTCH2,TGFB2,IL1A,MAP2K3,MIR192,CDH13,STAT6,PROX1,CREBBP,PRDM4,HAND2,MTDH,MBD3,HCFC2,GREM1,ZNF345,ZBTB18,ADRB2,IRF2,MSL2,TRIM37,NFKBIB,WASL,SOX2,DHX9,ABHD14B,SPP1,HOXB1,DYRK1A,ESR2,MIR195,YTHDF2,NFYB,RFXAP,EZH1,PRIM2,LHX2,IER2,GTF2I,UPF3B,HEXB,NR4A2,ZNF668,LUM,EPO,TGFB1I1,IKBKB,MYRF,EGR1,TRIM15,CNOT7,TRIM44,SP1,MIR212,RBM3,PPARG,CCNA2,EPCAM,TRA2A,BTG2,RNF20,TRIM52,DCP2,MIR193A,RNF187,MIR106A,JUP,FOXJ3,RHOG,PGR,ZNHIT1,ITGA6,VPS72,MITF,MIR1-1,SOST,NCBP2,UBP1,ACTL6B,TAF7,TP53,ZBED3,KLF4,PAX9,DNAJC2,JADE1,TFPT,ARF4,TRIM27,DDIT3,TLR4,CNOT8,MIR340,SRSF1,P2RY1,ZNF574,MIR26B,HELT,TRIP4,ZNF473,ACSS2,SIX5,VGLL2,HSPA8,CSRNP3,RAP2C,ILK,FBXW11,TRA2B,MIR424,OGG1,CITED1,RB1,SUPT5H,CXCL10,NFYA,MED4,ZNF593,NDN,CDK9,USP16,FOXC2,IRF4,MIRLET7C,NEUROG2,PLSCR1,ZBED4,TFDP2,BRD3,MIR214,NLRP3,LDB1,CEBPG,ACVR1,MIR191,MIR145,MSX1,PDE12,RUVBL1,ING1,PHB1,DDRGK1,HMGA1,ACTB,LBH,NAA15,RBBP7,TNF,CRLF3,ARMCX3,RAF1,CX3CL1,SF3B1,RBPJ,YAF2,H2AZ1,IL10,ROCK2,MIR98,MED11,GABPA,HINFP,S100A10,GTPBP1,ZNF304,HRAS,MIR23A,GTF2A2,BATF,HMGB1,FGF7,YTHDF1,MIR495,TOP2B,INO80C,PLAC8,ZNF770,SSBP4,GABPB1,UCN,MIR210,CD80,TP53INP2,MED27,DXO,POU5F1,TCF21,FOXD3,GTF2A1,SSBP3,SMYD3,ELK1,MAD2L2,LYAR,MED29,RIGI,PAX6,MIR204,MIR423,WNT10B,MEF2B,ZNF507,CDC73,MIR96,MIR30B,MIR519D,ECD,DNM2,TNFRSF1B,SMARCD3,PLCB1,TLR9,MLLT6,HDAC3,ZNF24,MYBL2,ZBTB16,CREBL2,RGCC,TP53INP1,RFX5,ID4,EFCAB7,GTF2F1,IL6,ZFP64,ZNF267,CD86,SOX21,THRAP3,MIR223,ZNF513,RNASEL,LDB2,ELF1,MIR185,RNF14,UBE3A,MIR130B,HAX1,MTA3,ZNF263,NEUROD2,E2F4,SF3B4,SMARCE1,RXRG,PPARA,CXXC1,PRL,PPP1R12A,ACTL6A,OTX2,JUNB,HAS3,JUN,FOXP3,CD274,DMAP1,MIR885,KPNA6,CDK5RAP3,DVL2,GSK3A,RGMA,ATF1,MED31,E4F1,MORF4L1,LMO2,TAF11,JAK2,STAT1,CAND1,FGF1,MIR125A,NR1H2,LRP6,CDK12,SS18,IL2,MIRLET7B,CYTL1,PSMC3,MIR130A,AR,TRIM24,RRN3,HNRNPAB,MIR497,RIOK2,XBP1,AATF,CREBZF,LMO4,MET,MIR320A,MIR206,MLLT11,PID1,RBBP4,CTNNB1,BACH1,HYAL2,MAX,VDR,NEUROD6,CREB3L4,MT3,TEF,TOX,SNX5,EP300,IGF1,HMX2,NFKBIA,ENY2,CNOT2,WDR77,GRSF1,NAA16,KARS1,SIRT7,PRMT5,FUBP3,EXOSC8,INO80E,SMAD4,SERTAD2,MIR211,UBE2V1,CEBPE,PPP3CA,WNT7A,DYRK1B,AKT1,IL1B,TGFB3,BMPR2,IL23A,MTA2,TFE3,VEGFA,SLC38A2,EXOSC3,CCAR1,SMAD9,SOX3,NFE2L2,MIR137,FGF23,BMPR1A,MIR181C,BCL9,MECP2,SMARCB1,DEK,IFI16,ELK4,ZNF319,SOX14,FZD4,LMO3,NIBAN2,RFXANK,METTL14,ACTR2,TRUB1,CAMK1,NR2E1,PIK3R1,MIR625,PIK3R2,KLF1,MIR100,SETD4,IRF1,PQBP1,OSM,UTP15,AFAP1L2,STK16,ROCK1,SUPT4H1,MEF2A,MIR135B,ETV6,MIR34B,IL17F,TAF10,APEX1,MED17,ZNF175,ATF4,TRIM21,MIR140,TFEB,SQSTM1,HNRNPK,POLR2G,IL18,ELK3,ZNF609,SMARCA5,SERTAD3,MIR491,TERT,PIH1D1,NFKB1,MIR16-1,SUPT3H,PABPC1,HLF,IRF2BPL,TFCP2,BMPR1B,PSMC5,CHCHD2,FOS,HCLS1,POU1F1,NUP62,ARL2BP,WBP2,PIAS1,AKAP8L,RNF10,TBK1,RNF40,STAT5A,PLAGL1,MIR181D,MRPL12,CD38,FXR2,TRAF6,MIR373,TLR2,ZNF287,NDP,TRMT112,TAF9,TNRC6C,UBE2L3,WNT2,HNRNPD,TRIM32,MED9,SERTAD1,TRIM62,MED23,CNOT6L,YES1,BIRC2,NIF3L1,PCBD1,CRTC2,TCEA1,SMAD3,MIR24-1,CSRNP1,NME2,ATF3,PRDX6,NKX3-1,FOXA3,SGF29,EAF2,PRR5L,PKNOX1,TESC,NOG,CREB3,TRIM5,MED22,PITHD1,NR1I3,MED10,MED30,CD40,KLF10 |
| 6.675e-04 | -7.31 | regulation of DNA-templated transcription initiation | biological process | GO:2000142 | 81 | 38 | 18204 | 5365 |
HNF1B,SUB1,JUN,MDC1,HMGB1,PPM1D,MED30,ZNHIT1,MED10,TAF2,HEY2,MED21,MED11,MED22,GTF2A2,CDK4,RRN3,CTNNBIP1,MED4,TAF11,MED29,TAF7,TAF10,MED31,NFKBIA,MED17,TP53,WNT10B,CAND1,NFKB1,MED9,MITF,TAF9,ZNF451,MYC,GTF2A1,MED27,MED23 |
| 6.683e-04 | -7.31 | SMN2 (survival of motor neuron 2, centromeric) | protein interactions | 6607 | 110 | 47 | 19454 | 5460 |
SMN1,SNRPG,LSM4,KRAS,DHX9,HBP1,ZRANB2,GEMIN7,RHOBTB1,SNRPE,PDHA1,COMTD1,TP53,CDC5L,LSM5,SNRPD3,RHOH,SYNCRIP,PHB1,LSM3,HAX1,RPS2,SNRNP70,XPO1,FNDC11,COIL,VPS28,FBXW7,CD40,LSM2,RND2,EHHADH,SNRPN,LRIF1,SNRPB2,APEX1,SNRPD2,SNRPD1,POP7,RIT1,PPIG,GEMIN8,LSM6,CHTOP,NTAQ1,SNRPB,CUL3 |
| 6.683e-04 | -7.31 | SNAPC1 (small nuclear RNA activating complex polypeptide 1) | protein interactions | 6617 | 110 | 47 | 19454 | 5460 |
MARS1,RP2,KDM1A,EMG1,EXOSC4,PRIM2,RPA3,SNAPC1,USE1,COX6C,PIP5K1A,ACTL6A,GTF2H4,RPL10,RPL22,TRIM29,PSMD4,ZMAT5,ZNHIT6,EXOC8,SNRPB,CARS1,MRPL22,RPS27A,TTC4,CTNNBL1,CDC40,KRAS,RPL3,SNAPC3,LTO1,RINT1,SDHC,SNIP1,MRFAP1L1,SNAPC2,GNG10,SNAPC5,RPSA,MED9,CENPM,RB1,RPL32,SSBP1,MPHOSPH6,RPL24,RBM17 |
| 6.683e-04 | -7.31 | TIPRL (TOR signaling pathway regulator) | protein interactions | 261726 | 110 | 47 | 19454 | 5460 |
ZKSCAN1,RPA3,COMMD2,HSPA8,SRM,MCMBP,GTF2I,UFL1,PRDX3,RPA2,LMNA,PSMB7,ACACA,EIF4A3,CREB1,OPTN,CCNF,PRDX2,RAB11A,CUL3,RNF40,CCT2,SORD,UBE2H,PABPC1,ZC3H7A,XPNPEP1,CSE1L,HUWE1,CTSC,CAPZA1,TFG,RNF20,CCT5,FASLG,PPP2R1A,PPP4C,PPP2CB,EEF1AKMT3,SSU72,ATP6V1A,IGBP1,CORO1C,PRNP,EGLN3,PRPF19,PRDX1 |
| 6.702e-04 | -7.31 | Ybx1 (Y box protein 1) | protein interactions | 22608 | 60 | 29 | 19454 | 5460 |
YWHAZ,MRPL18,IGF2BP1,MRPS26,HNRNPAB,MRPS35,MOV10,CLPX,MRPL16,MATR3,NOP58,MRPL24,DKC1,CCNF,SYNCRIP,ZNF326,MRPS34,MRPL47,MRPL12,HNRNPK,HNRNPF,TRA2B,HNRNPA0,HNRNPDL,MRPS7,PABPC1,DHX9,DDX5,MRPS18B |
| 6.702e-04 | -7.31 | Ufl1 (UFM1 specific ligase 1) | protein interactions | 67490 | 60 | 29 | 19454 | 5460 |
DYNLL1,ERLIN1,TAF11,KLHL7,STT3A,QSER1,SEC61A1,RRAS2,RTRAF,CDK5RAP3,ABCG2,UBFD1,PRSS1,RBM7,PRPF31,ZNF668,DDRGK1,KPNA6,KDM1A,DGCR8,CAMK2G,UFM1,PHB2,PRPS1,CHMP1A,VPS54,AKR7A2,ABHD6,ERLIN2 |
| 6.702e-04 | -7.31 | F11R (F11 receptor) | protein interactions | 50848 | 60 | 29 | 19454 | 5460 |
IL12A,ZDHHC17,KRAS,TMEM147,RABAC1,PICK1,JAGN1,CASK,PRKCA,MMP14,DDX39A,PGAP2,WIF1,DIRAS3,ARF6,F11R,SGTA,CAMLG,HRAS,RAB35,TMEM100,DNAJB6,OSGEP,RHOB,SLC35A1,CD81,CSNK2A1,MBLAC2,RAB2A |
| 6.702e-04 | -7.31 | MSRB2 (methionine sulfoxide reductase B2) | protein interactions | 22921 | 60 | 29 | 19454 | 5460 |
ACAA2,NDUFS6,LYPLA1,CDC42,TRAF2,GNPNAT1,NEDD8,ZDHHC17,RAD21,PEBP1,PTRHD1,COA4,COX17,AK2,TST,LAMTOR2,AK3,LYPLAL1,LGALS3,PRNP,TXNDC12,DBT,CAV1,HDHD5,CYB5R3,COMT,DSTN,MAP1LC3A,RAC2 |
| 6.702e-04 | -7.31 | KCNA5 (potassium voltage-gated channel subfamily A member 5) | protein interactions | 3741 | 60 | 29 | 19454 | 5460 |
KCND3,TP53,CYB5R1,YIPF4,TFRC,RAB4A,KCNAB1,ADCY3,TMX2,ATP2B4,DLG1,PRKCB,HSPA8,RAB5A,DYNC1I1,RHBDD3,NT5C3A,TMEM107,DOLK,SNTA1,HSP90AA1,KCNA3,STUB1,KCNA2,DLG4,UBE2I,PRKCQ,SRC,CAV1 |
| 6.702e-04 | -7.31 | PHRF1 (PHD and ring finger domains 1) | protein interactions | 57661 | 60 | 29 | 19454 | 5460 |
DDX23,NLRP3,PRPF19,CSNK2A1,COPS5,SNRNP40,POLR2I,POLR2B,ERH,ESR2,VIRMA,RPRD1A,POLR2L,DLST,CSNK2B,RPRD1B,POLR2D,POLR2C,POLR2G,RPAP2,THRAP3,SAP18,RIGI,AATF,SNIP1,XRCC5,SIRT7,NBN,EWSR1 |
| 6.718e-04 | -7.31 | TMEM131 (transmembrane protein 131) | protein interactions | 23505 | 139 | 57 | 19454 | 5460 |
PTAR1,ST7,SEC62,CDC42,OTULINL,TMEM106A,SSR1,CHRNB2,DERL1,CLEC12B,STAU1,GPIHBP1,HSPA5,TOMM20,GGH,PPP1CC,BICD2,TAFAZZIN,SDF2L1,MAPRE1,CNOT6,ST8SIA5,SEC61B,RMDN3,DNASE1L1,SEC63,ESR2,DNAJC25,GABARAPL1,SFTPC,RPN1,STIM1,NCR3,TMT1A,TMEM87A,CNOT7,RIGI,SIAE,FKBP8,CNOT6L,FKBP2,CFC1,CNOT2,LRRTM1,CNOT8,TNNC2,LYZ,PTPN1,THOC2,RAC2,HSD17B11,DNAJC1,DNAJB9,OS9,FIBIN,TMPO,EGLN3 |
| 6.734e-04 | -7.30 | Signaling by Interleukins | REACTOME pathways | R-HSA-449147 | 525 | 199 | 10285 | 3229 |
CXCL10,FGF3,TRAF6,IL2RA,PSMB9,MAP3K11,IL1B,CSF2,JAK1,COL1A2,PSMD12,ICAM1,SHC3,IL6ST,RAG1,SPTBN1,PSME1,ANGPT1,IRF4,PSMD14,PTPN11,PELI1,STAT5A,TNF,PPP2R1A,UBB,JAK2,PSMB1,TNFRSF1B,CCL2,CRKL,CCR1,SOX2,IL6,PSMC4,PSMA4,CCL20,PSMB11,FGFR1,PSMB6,PSMA2,IL17F,IL4,RASGRP3,IKBKB,SHC1,BCL2L1,CCL11,PSMA1,OSM,IL3,PSMD4,OPRM1,PHB1,TAB2,IL18,LAMTOR3,MAP2K6,CCR5,CUL3,PSMC1,CCR2,BCL6,PPP2CB,HRAS,STAT6,UBE2V1,PSMD1,PSMB2,HSP90AA1,PIK3CA,PEA15,AKT1,IL20RB,CCL3,PSMD10,CD36,CCND1,IL13,MMP9,KRAS,MAP2K1,FGF22,SYK,IL23A,RAF1,PELI3,PIK3R2,IL2RG,SOCS3,BIRC5,TAB1,FGF1,DUSP6,PAQR3,IRAK4,JUNB,NFKB1,MET,IL1A,SPTAN1,IL15,PSME2,HBEGF,PSMD6,HSP90B1,SPRED2,MAP3K3,MYD88,DUSP10,SQSTM1,NEFL,CD4,CDKN1A,PIK3R3,FGF7,MYC,BATF,STAT1,RAP1A,PPP5C,SKP1,IL12B,FGF17,CD80,PSMD7,TIMP1,IL18BP,IL1R2,HSPA8,CBL,SOCS5,CXCL8,PSMB7,INPPL1,PSMD3,H3C1,CCL19,PIK3R1,FOS,CXCL1,PSMA3,PSMB5,PSMB10,NDN,IL2,PSMC5,RHOU,FBXW11,CSK,BRAP,IL22,DLG4,PSMB4,SEM1,VEGFA,DUSP1,PSMC3,TP53,TOLLIP,CD86,RPS27A,IL1RAP,SPRED1,MCL1,FGF16,IL12A,CAMK2G,IL2RB,VWF,UBE2N,IL5,LAMTOR2,KIT,IL34,IL15RA,PSMA6,IL7,FRS3,DUSP9,SRC,FGF10,YWHAZ,RAP1B,IL10,WDR83,CNTFR,UBA52,YWHAB,STX1A,CCL5,PPP2R5A,FASLG,PSMA5,FGF23,PPP2R5E,YES1,PEBP1,PSMB3 |
| 6.744e-04 | -7.30 | CCNH (cyclin H) | protein interactions | 902 | 93 | 41 | 19454 | 5460 |
RIGI,MNAT1,TFG,PDHB,KRAS,PSMA1,HNRNPF,CDK20,PICK1,RPA3,GTF2H5,SMARCB1,CDK8,RPA2,HOXB1,CDK7,GTF2E2,PI15,GTF2H4,SUPT5H,TP53,CDK9,POLR2B,CETN2,RHOH,CDC7,GANAB,CSNK2B,ZNF655,CDK6,GTF2H2,GTF2F1,SSX2IP,BRCA1,AR,ERCC3,MYC,SFN,TRIM8,NDC80,CCNB1 |
| 6.744e-04 | -7.30 | ARPC1A (actin related protein 2/3 complex subunit 1A) | protein interactions | 10552 | 93 | 41 | 19454 | 5460 |
TOP3B,ACTN4,MAP1LC3B,SOX2,ARPC3,ACTR2,EZH2,RPA2,CNDP2,NUPR1,SH3GLB1,RPA3,ARPC2,SQSTM1,THG1L,STK26,MIS12,KRAS,G3BP1,GON7,OLA1,MYC,CALR,AR,ACTR3B,USP14,BAG3,XPO1,ARL6IP6,ARL14EP,YWHAB,CALU,CTTN,CCNF,TACO1,ACTB,TAX1BP1,DAPK1,ARL6IP5,ESR2,SH3BGRL |
| 6.745e-04 | -7.30 | rough endoplasmic reticulum membrane | cellular component | GO:0030867 | 24 | 15 | 19108 | 5553 |
RP9,TMEM97,SEC63,RPS29,RPL27,MACO1,SEC61B,SRPRB,RPS26,SEC61A2,SRPRA,CCDC47,SEC61G,RPS28,SEC61A1 |
| 6.745e-04 | -7.30 | proteasome accessory complex | cellular component | GO:0022624 | 24 | 15 | 19108 | 5553 |
PSMD10,PSMC4,PSMC3,PSMC5,PSMD1,ADRM1,PSMD4,PSMD3,PSMD7,PSME1,PSMD12,PSMC1,PSME2,PSMD14,PSMD6 |
| 6.745e-04 | -7.30 | CCNE2 (cyclin E2) | protein interactions | 9134 | 27 | 16 | 19454 | 5460 |
CDK1,TFDP2,CDKN1B,H1-1,CKS1B,HNRNPC,DDX39A,FBXO7,CDKN1A,FBXW7,SUMO2,SUMO3,ZDHHC17,CDK9,PCNA,PTEN |
| 6.745e-04 | -7.30 | TICRR (TOPBP1 interacting checkpoint and replication regulator) | protein interactions | 90381 | 27 | 16 | 19454 | 5460 |
SPPL3,KRAS,MIF,EGLN3,ESR2,VIRMA,H2BC14,CDK8,YWHAZ,RIT1,TOPBP1,YWHAB,CUL3,YWHAH,YWHAG,CCNA2 |
| 6.764e-04 | -7.30 | negative regulation of cell migration involved in sprouting angiogenesis | biological process | GO:0090051 | 45 | 24 | 18204 | 5365 |
MIR320A,MIR20A,MIR193A,MIR495,MIR205,STARD13,MIR885,MIR206,MIR503,MIR221,KLF4,MIR149,MIR146A,MIR361,MIR497,PDCD10,MIR29C,MIR188,SPRED1,MIR200C,HDAC5,MIR16-1,MIR15A,MIR424 |
| 6.770e-04 | -7.30 | TIR | smart domains | SM00255 | 21 | 13 | 9717 | 2575 |
SARM1,IL1RAP,TLR4,TLR9,TLR6,TLR5,TLR8,TLR2,TLR1,TLR7,TLR10,TLR3,MYD88 |
| 6.774e-04 | -7.30 | KHSRP (KH-type splicing regulatory protein) | protein interactions | 8570 | 272 | 101 | 19454 | 5460 |
PPIA,STK3,EED,TRAPPC10,SIN3A,FUBP3,PHB1,CBL,HNRNPD,DROSHA,HNRNPA1,DDRGK1,PIK3R1,WWP2,CPLX1,TNF,CHCHD2,ETFA,GADD45A,KLHL12,EZH2,CHMP4C,EXOSC3,GFPT1,JUN,LGR4,RAF1,ESR2,PRDX2,SNRNP40,TENT5C,ARF1,HTRA2,CIRBP,BRCA1,BTF3,MYC,CUL2,CUL3,UFL1,STAU1,HSPA8,PSMA3,NUP50,EP300,FOS,EIF4B,PIH1D1,CTBP1,PPARG,NEK7,DUSP14,WDR77,CDK9,MBD5,FZR1,CAND1,PRNP,CD274,TRAPPC2L,COPS5,CD81,MPG,MDC1,HUWE1,NEDD8,TGFBR2,HAPSTR1,RAB1A,SNIP1,FAF1,BACE1,TRAPPC13,TFCP2,UBL4A,TP53,VIRMA,KCTD9,PTEN,UBE2I,CCNF,IGF2BP1,UBE2H,IL2,RUNX1,AR,HMOX2,AATF,DGCR8,RNF113A,BAP1,RPA3,SIRT7,UBE2M,HEXIM1,RPA2,IDH2,GABRA1,CDK7,CFTR,MAEL |
| 6.793e-04 | -7.29 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological process | GO:1903588 | 26 | 16 | 18204 | 5365 |
MIR503,MIR16-1,MIR149,MIR15A,MIR424,MIR361,MIR497,MIR29C,PDCD10,MIR193A,MIR495,MIR222,IL12B,MIR24-1,IL12A,MIR342 |
| 6.797e-04 | -7.29 | EPHA2 (EPH receptor A2) | protein interactions | 1969 | 350 | 126 | 19454 | 5460 |
DNAJC5,RAB2A,AKT1,TAS2R7,PTPN11,EPHA2,AP2A1,STK11,MECP2,PTEN,GAB1,TUBA1B,RHOJ,CDC42,KDELR2,ATG16L1,DUSP18,HEXIM1,DYRK2,MET,RPA2,VPS4B,USE1,FGFR1,RAB9A,TNFAIP1,RHOU,NF2,FTSJ1,PIK3R2,LAMP3,HDAC6,STYK1,BECN1,SHC1,TIAM1,GATAD1,NUDT9,CDK6,TES,RAC2,EFNA3,HRAS,MAP2K6,LMAN1,EPHB6,STX6,CAV1,FZR1,ARF6,GRM1,MAP2K3,TP53,CDK4,NUPR1,SIGLECL1,NTRK2,IGF1R,DDR1,SOCS2,PDE2A,DUSP19,RAB3B,SRPRB,MYC,PIK3R3,RAB11A,NTRK3,HSP90AA1,SLC7A11,LAMTOR1,RHOB,AP2M1,LMBR1L,GNG12,EFNA5,TIMM21,RND2,CLDN4,USP6NL,DUSP14,BET1,RAB5A,TMEM185A,ARRDC3,PEBP1,STX7,ITGAV,STAU1,SSR3,DUSP26,CTNNB1,LAMP2,PIK3R1,RAB5C,MRPS35,CBL,RHOG,GJA1,TSG101,PSME2,RAB35,WDR6,DIRAS3,MACROD1,CDK17,RHOH,NCSTN,EEF2,RAF1,MAGEB10,RND3,CCR1,ITGB5,CRKL,AP2S1,HGS,NUDT19,RAB4A,MYO1B,TMT1A,CDKN2C,FLOT1,EPHA4,KRAS,ZBTB14 |
| 6.814e-04 | -7.29 | SLC6A8 (solute carrier family 6 member 8) | protein interactions | 6535 | 142 | 58 | 19454 | 5460 |
LMBRD2,TPRA1,CD59,RND2,OTULINL,TRAM1,SEC62,CDC42,GRPR,STX7,FADS2,RHOU,RAB5A,RAB9A,RHOB,LAMTOR1,GPR17,RAB11A,RAB2A,KDSR,DNAJC5,RHOJ,LGALS3,CHP1,CHRM5,SEC61B,RAB4A,RPN1,RND3,TOP3B,PREB,YIPF3,UBIAD1,RAB3B,KRAS,FLOT1,TMT1A,COX8A,RHOG,POR,RAB5C,PTDSS1,LAMP2,LAMP3,RHOH,ARF6,SPPL3,OS9,CAV1,DIRAS3,ILVBL,LMAN1,STX6,RAB35,RAC2,GJA1,HSD17B11,G6PC3 |
| 6.814e-04 | -7.29 | STRN3 (striatin 3) | protein interactions | 29966 | 142 | 58 | 19454 | 5460 |
EIF1AX,METTL15,GABARAPL1,PPP2R1A,CCT5,TMEM126A,HSPE1,CAMK2G,PSMA5,RUVBL2,SIKE1,CCT8,CTTNBP2,PPP1R12A,USP15,PDCD10,CTNNB1,STK4,BTF3L4,EXOC1,XPO1,COPS5,STK3,CCT7,SLMAP,PRNP,TCP1,TNKS,TRAF3IP3,PPP2CB,TNIK,CHMP1A,RPA2,SNAI3,PPP2R2C,STK26,RTN4,HCFC2,RPA3,BAP1,ENDOD1,MYO6,STK24,CCT2,FAS,ISCA2,PRPF31,HNRNPC,FGFR1OP2,ESR2,CTTNBP2NL,DYNLL1,B4GALT4,MAP3K3,MOB4,RMDN3,TUBA1B,CTTN |
| 6.814e-04 | -7.29 | SACM1L (SAC1 like phosphatidylinositide phosphatase) | protein interactions | 22908 | 142 | 58 | 19454 | 5460 |
VIRMA,TAX1BP1,MANSC1,COPE,IL2RA,CYB5R3,LMBR1L,RIT1,SCFD1,MFSD14B,CD226,UFD1,SCN3B,CUL3,TM9SF4,CREB3,VEZT,TMEM167B,STAU1,FMO3,LPAR1,HSCB,SLC7A1,EP300,HSPA8,VIPR1,RPA3,JAGN1,TMX2,PRKCA,GPR35,RPA2,VAPB,TMEM115,LMNA,P2RY12,CFTR,OTULINL,MTERF2,OSBP,TES,SPINT2,LDLR,HSD17B11,P2RY1,DDRGK1,SLC35A5,COPS5,CCR6,FAM20C,DHRS7,ICAM2,SACM1L,KRAS,LPAR2,COX4I2,TP53,CCDC47 |
| 6.814e-04 | -7.29 | GOLM1 (golgi membrane protein 1) | protein interactions | 51280 | 142 | 58 | 19454 | 5460 |
BCL2L1,NDUFV2,SLC13A5,DEXI,TMPO,AIG1,ANKRD46,EIF2B2,TSG101,NRSN1,DCK,KCNA2,GEMIN7,CTLA4,SFTPC,FUT9,TMEM59,TMEM176A,NEU1,INSIG2,UST,FLOT1,SLC7A14,TF,TMEM147,SLCO3A1,LACRT,CIAO1,MED22,VIRMA,NRSN2,RPL13A,LMBR1L,CDIPT,CHRNB2,RPA2,EIF2B3,TMUB2,SEC62,CNPY3,EIF3J,FTH1,CLDN4,PGRMC1,TMUB1,SLC7A1,RNF5,NINJ1,CLEC12B,DESI1,HMGB1,CLK1,LSM12,LCN1,SLC39A9,JAGN1,GRAMD2B,TSPAN15 |
| 6.891e-04 | -7.28 | cell chemotaxis | biological process | GO:0060326 | 216 | 86 | 18204 | 5365 |
SLC12A2,KIT,CCL25,CCR5,CKLF,CCL21,CXCR3,RPL13A,CRKL,ADGRE2,NINJ1,RAB13,CCR2,SFTPD,CCL19,CCL28,NRP1,CCL2,PIP5K1A,CXCL10,DEFB114,CCL4L1,CHGA,CCR1,CCL18,IL1B,CXCR1,CCL23,EPHA2,CXCL12,CXCR6,CCR4,HMGB1,CH25H,SYK,ELMO2,CXCL1,CCL20,CCR7,FOLR2,CXCR4,S100A8,SEMA5A,CCR6,XCL1,IL10,TGFB2,CX3CL1,CCR3,DPEP1,CXCL11,CCL24,CX3CR1,CCN3,CCL1,RHOG,PRKCQ,GAB1,CXCL3,HBEGF,PTN,CXCL13,JAML,CCL27,SRP54,TPBG,LGALS3,VEGFA,PPIB,SCG2,CCL3,MSMP,ACKR3,CXCL14,PIK3CG,PDE4B,CCL8,CCL11,FCER1G,CCL5,CXCL8,LPAR1,CXCL9,PPIA,IL6,CCL17 |
| 6.901e-04 | -7.28 | GSTM3 (glutathione S-transferase mu 3) | protein interactions | 2947 | 145 | 59 | 19454 | 5460 |
BRCA1,PSMD14,UBE2H,CUL3,PTPN11,PSMA4,CARS1,BAG3,TUFM,GSTM5,ESR2,VIRMA,GSTM4,ENO1,RAN,CCNF,CLVS2,RNF7,GSTM2,RPA2,KCTD12,PIH1D1,RARS1,OXSR1,PRDX3,UFL1,HSPA5,RPA3,DDX5,HSPA8,LANCL2,AGR2,IKBKB,MAP4,NAB2,VCPIP1,CIAO3,MOV10,UBXN6,GSTM3,PDIA3,GAPDH,MPG,HDAC6,COPS5,PLEKHF2,CAND1,HNRNPL,DHX15,G6PD,NLRP2,GNB1L,CCR1,EEF2,MSX2,DDX39A,MAP1LC3B,PABPC1,RAB1A |
| 6.901e-04 | -7.28 | CTSS (cathepsin S) | protein interactions | 1520 | 145 | 59 | 19454 | 5460 |
TP53,ACTN4,ERLIN2,RPN1,ARPC3,SOD2,SELENOF,PLD3,SLC25A11,MYO1B,ERO1A,BAG2,ERP29,SRPRB,PRDX4,KARS1,PDIA3,CALR,CST3,TUBG1,BGLAP,MT1X,STT3A,COQ8A,PHB1,MRTO4,XPO5,CHID1,SPTAN1,LMAN1,OS9,TOMM22,CNPY3,HSP90B1,FKBP10,FKBP1A,DNAJC3,EMC1,AIF1L,RNF5,RPF2,MLF2,SDF2L1,SLPI,BRCA1,MYO6,DNAJC10,XPOT,SERPINH1,MDH1,CALU,GXYLT1,IRF2,SEC61A1,GANAB,CTSB,AKR1C2,TXNDC12,B4GAT1 |
| 6.944e-04 | -7.27 | bronchus | COSMIC cancer mutations | bronchus | 22 | 14 | 16828 | 4835 |
AKT1,FBXW7,KIT,MET,CTNNB1,TP53,PTEN,FGFR1,PIK3CA,HRAS,KRAS,SMAD4,STK11,MAP2K1 |
| 6.979e-04 | -7.27 | STK4 (serine/threonine kinase 4) | protein interactions | 6789 | 148 | 60 | 19454 | 5460 |
SGMS1,USP46,MAP1LC3A,KIF3B,STK3,ATP5PD,SLMAP,EGLN3,SAV1,MAP1S,STOML2,RASSF4,ACTR3B,STK4,YWHAH,NDUFV2,HDAC6,YWHAG,XPO1,TRAF6,YWHAB,MAP1B,PICK1,AKAP12,PAEP,PSMD12,TP53,KIF2A,MAP1LC3B,H2AX,ZNF189,CRYBB3,CCNF,PHKB,MOB4,TAB1,CTTNBP2NL,FGFR1OP2,AKT1,MYC,PSMD14,FBXW11,SPCS3,UBE2H,SNX5,CCDC174,KIF3C,MYH2,SPCS2,HSPA8,GABARAP,HSPA5,DDIT4L,ATG16L1,IL2RG,MYH1,VPS18,VAPB,DYRK2,SH3GLB2 |
| 6.984e-04 | -7.27 | positive regulation of interleukin-6 production | biological process | GO:0032755 | 100 | 45 | 18204 | 5365 |
TLR2,TRAF6,MYD88,SETD4,TLR9,IFIH1,XBP1,MIR657,AIF1,LILRA2,TLR8,TIRAP,SPHK2,MAVS,TLR7,TYROBP,RIGI,TICAM1,TLR1,CD36,UCN,IL1B,BCL10,HSPD1,DHX9,SYK,HMGB1,TLR4,IL1RAP,LEP,AGER,PYCARD,PTPN11,TLR6,IFNG,MIR144,IL1A,TLR3,IL17F,TNF,SELENOK,TMEM106A,IL6,HYAL2,CLEC7A |
| 6.994e-04 | -7.27 | regulation of synaptic plasticity | biological process | GO:0048167 | 219 | 87 | 18204 | 5365 |
NTRK2,MIR324,SYT4,ANAPC2,PSEN1,EGR2,MIR30B,PTN,PDE9A,NR2E1,NPTN,MIR342,MIR421,NCSTN,SLC38A1,CHRNA7,PRRT1,MEF2C,S100B,TYROBP,NCDN,MECP2,SIPA1L1,NEUROD2,NETO1,PRNP,SNAP25,SLC4A10,DLG4,SQSTM1,ATF4,YWHAH,LARGE1,DAG1,ADORA1,STAU1,ABHD6,CDC20,KCNB1,LRRTM1,YWHAG,PPFIA3,UBE3A,EPHA4,ARF1,RIMS3,PICK1,CBLN1,GRM2,PAIP2,RAB3A,MIR320A,GRIA1,CD38,CD2AP,KIT,TNR,RAB5A,FXR2,CPLX2,DRD1,MIR545,SYNGR1,IGSF11,STXBP1,SYP,EIF4EBP2,VAMP2,JPH4,NOG,CHRDL1,AGER,HRAS,MME,FAM107A,YTHDF1,CDK5,MAP1B,MIR95,CX3CR1,SLC1A1,LRRTM2,RIMS4,KRAS,NSG1,CX3CL1,KCNJ10 |
| 7.015e-04 | -7.26 | TEFM (transcription elongation factor, mitochondrial) | protein interactions | 79736 | 217 | 83 | 19454 | 5460 |
METTL15,SERPINA3,PPIF,MRPL47,NDUFA2,ETFB,MRPL11,RAF1,ATP5PB,NDUFA12,NDUFS3,NDUFS6,CRABP2,PDHA1,COX8A,MRPS18B,HINT2,HECTD3,MAEA,IMMP2L,IMPA2,MRPS17,ETFA,KGD4,MRPS33,DDRGK1,NDUFV2,INO80E,MRPS35,COX5A,GRSF1,MTRF1,CLPX,DRG1,MRPS26,CHCHD1,SNRNP70,COX4I1,MRPS9,MRPS23,RMND1,MRPL24,NDUFS8,MRPL50,RPS16,MRPL12,FAXC,GKAP1,NDUFA5,MTRES1,APOBEC3C,MRPS34,SDC2,SPCS2,TWNK,MRPS7,MRPL20,POLDIP2,AZGP1,FBXW7,MRPL41,RPL4,NDUFS2,NME4,PPP1CC,CUL3,PMPCA,PYCR2,PYCR1,AUH,MTG2,KLK5,MRPS25,MRPS16,MRPS28,DLST,CCDC90B,TACO1,PSPC1,RPL19,RPP25L,RPGRIP1L,MRPL23 |
| 7.062e-04 | -7.26 | NCAPD2 (non-SMC condensin I complex subunit D2) | protein interactions | 9918 | 214 | 82 | 19454 | 5460 |
CCAR2,SUMO2,CDC5L,EEF1AKMT3,PSMD7,SHC1,USP15,POU5F1,EMC4,PSMD3,CALR,UBXN6,EIF3D,ATG7,CSNK2A1,KPNA2,G3BP1,KRAS,RBBP7,RAD21,PSMD12,VTA1,HSPD1,HAPSTR1,MOB3C,PSMC3,CYB5B,MTA2,KBTBD4,TOP3B,COMTD1,PPP2R1A,NUP153,ACTR1A,SOX2,RBBP4,BMP1,FBXO22,MATR3,VIRMA,DPEP1,NFKBIB,CIB2,LMBR1L,CCNF,GANAB,PRMT5,STK24,IVNS1ABP,KCNJ2,UBE2H,RPS5,NRP1,PTTG1,GPR17,MYC,SNRPB,MCM4,PSMD1,SMC4,FBXW7,PSMC1,SIRT7,BAP1,CXCR4,RPA3,MEA1,AKAP1,HSPA8,TXNL1,METTL14,USE1,CDK1,RPA2,HECTD1,ACACA,HEXIM1,CFTR,NEK7,CDC42,RFXANK,SNRNP27 |
| 7.062e-04 | -7.26 | RFC4 (replication factor C subunit 4) | protein interactions | 5984 | 214 | 82 | 19454 | 5460 |
DDX1,CD58,BRD3,H2AC4,SNRNP70,HDAC6,DDRGK1,MPG,WWP2,CDK9,CDC5L,FZR1,RPS16,EIF2B2,TOP1,SUMO2,TES,H2AZ1,ILF2,MOB3C,RNF8,RAD1,TAF2,NCSTN,RPAP2,SOX2,RAF1,CDK4,TP53,MEPCE,PSMD12,RFC2,MSH6,SSRP1,MDC1,RFC3,G3BP1,KRAS,EPHA4,H3C1,PCNA,RAB27A,ABCE1,EWSR1,RUVBL2,DHX9,RTCB,ABCF1,ZBTB38,UBE2H,BRCA1,RFC5,MCM3,MYC,CUL3,ESR2,RPL10,TRIM29,RTRAF,PTEN,PSPC1,HEXIM1,RPL26L1,RPA2,EIF2B3,SETD3,CCNA2,CCND1,TANK,POLA2,RNF41,G3BP2,UFL1,SQSTM1,EP300,RFC4,BAP1,DVL2,RPA3,XRCC5,PML,NBN |
| 7.070e-04 | -7.25 | SOD2 (superoxide dismutase 2) | protein interactions | 6648 | 96 | 42 | 19454 | 5460 |
ACO2,CEP70,CFL1,AK3,CUTA,CFL2,PPIB,HTRA2,MDH1,OAT,TST,MT1X,NOL12,CYB5A,LDLR,TRIM24,CMBL,DSTN,LGALS3,CTSB,CYP4F12,PPIA,E2F4,UBL4A,H2AX,IDH2,ACAA2,RAB4A,PIR,ACACA,DCTD,SOD2,PEBP1,SOD1,GPX4,ZC3H11A,HSPE1,HMGB1,UCHL3,REXO2,ABHD10,STX7 |
| 7.070e-04 | -7.25 | RLIM (ring finger protein, LIM domain interacting) | protein interactions | 51132 | 96 | 42 | 19454 | 5460 |
CITED1,MDM2,CIB3,TRMT61A,LDB2,SPPL3,ZBTB17,PRNP,TUBB,SIAH1,PCBP4,NAA30,SNX17,SIN3A,CIB2,LHX2,UBE2D1,COMMD5,LDB1,ATG7,AKT1,UBXN6,LMO2,TNFAIP3,MYC,CUL3,UBE2E2,DNAJB2,FAM174A,UBE2K,UBE2D3,CDK20,TOLLIP,CST11,RLIM,UPF3B,ACACA,STAT6,ZC4H2,RFXANK,LNX2,RPS14 |
| 7.070e-04 | -7.25 | CHD1L (chromodomain helicase DNA binding protein 1 like) | protein interactions | 9557 | 96 | 42 | 19454 | 5460 |
EGLN3,CBX5,SRPK2,ESR2,CDC5L,HNRNPL,GMDS,TNKS,CCNF,H2AZ1,PARP2,EEF1AKMT3,ID1,KLK5,FOXP1,FAS,BTF3,API5,LAMP2,MYC,FAM174A,GPR17,CIAO1,TNKS2,SSRP1,RFC2,HSPA8,H2BC12,BAALC,RPA3,H2AC25,NDUFA4,XRCC5,RETREG2,RPA2,SDC2,CBX3,H2BC1,RNF146,INSYN2A,H2AX,RAF1 |
| 7.070e-04 | -7.25 | SARS2 (seryl-tRNA synthetase 2, mitochondrial) | protein interactions | 54938 | 96 | 42 | 19454 | 5460 |
COX4I1,CCNF,APEX1,LRWD1,TMEM237,EGLN3,SPTAN1,MATR3,DDRGK1,TUFM,NTAQ1,CUL3,AUH,IFI16,CALU,USP15,UBE2H,RIT1,PPTC7,IGF1R,EXD2,CCT8,HSPD1,RPA3,RAD21,AATF,UBE2A,KRAS,CHCHD2,UFL1,NF2,HSCB,TULP3,EEF1A1,E2F4,ATG16L1,RAF1,TOP3B,ILF2,PDHA1,UBE2B,RPA2 |
| 7.088e-04 | -7.25 | RNA Pol II CTD phosphorylation and interaction with CE | REACTOME pathways | R-HSA-77075 | 27 | 17 | 10285 | 3229 |
CCNH,POLR2G,POLR2C,GTF2F2,GTF2H4,POLR2F,GTF2H2,GTF2F1,POLR2L,POLR2I,GTF2H5,POLR2D,CDK7,SUPT5H,ERCC3,POLR2B,MNAT1 |
| 7.088e-04 | -7.25 | RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | REACTOME pathways | R-HSA-167160 | 27 | 17 | 10285 | 3229 |
ERCC3,SUPT5H,POLR2B,MNAT1,CDK7,GTF2F1,GTF2H2,POLR2D,POLR2I,GTF2H5,POLR2L,POLR2G,POLR2C,CCNH,GTF2H4,GTF2F2,POLR2F |
| 7.092e-04 | -7.25 | TNRC18 (trinucleotide repeat containing 18) | protein interactions | 84629 | 47 | 24 | 19454 | 5460 |
GATAD1,GSK3A,ING2,LYAR,PRNP,RBBP4,HNRNPL,RPL22,ESR2,VIRMA,COPS7A,AR,RNF113A,TGIF2LX,KRAS,CAMKV,RBBP7,RIGI,TOP3B,SAP30,EGR2,SOX2,ING1,NFKBIL1 |
| 7.093e-04 | -7.25 | PCNP (PEST proteolytic signal containing nuclear protein) | protein interactions | 57092 | 82 | 37 | 19454 | 5460 |
MOV10,MYC,RBM17,MARCHF5,RAB11A,COPS5,SNRPB,AHSA1,PAPSS2,SF3B6,PTPN1,CD274,SNRPD2,CHCHD6,CAND1,SNRPB2,SF3A1,RAF1,RBFOX2,ATG16L1,E2F4,CDC42,EZH2,LMNA,RPA2,SAMM50,CARD19,RPA3,PML,SF3B1,HSPA8,EMC2,NF2,HUWE1,STAU1,BCL6,HNRNPDL |
| 7.093e-04 | -7.25 | POLR3K (RNA polymerase III subunit K) | protein interactions | 51728 | 82 | 37 | 19454 | 5460 |
CHMP1A,PRKAG1,QRSL1,SDCBP,PIH1D1,POLR2D,POLR2G,PRKAB1,TRMT1L,POLR1D,DNAAF10,KRAS,POLR1H,FLOT1,PDRG1,HCFC2,FLCN,RPAP3,PFDN6,RIT1,POLR1B,PDCD10,PFDN2,PTTG1,ATP5MG,CENPP,BTF3L4,POLR3GL,CSNK2A1,POLR2I,POLR3F,POLR2L,RPRD1A,DNM2,POLR3H,POLR2F,POLR3B |
| 7.093e-04 | -7.25 | AGPAT3 (1-acylglycerol-3-phosphate O-acyltransferase 3) | protein interactions | 56894 | 82 | 37 | 19454 | 5460 |
CMSS1,CREB3,FAM241A,ENDOD1,MFSD14B,S1PR4,GPR89A,HSD17B11,SERINC1,MPP1,SPCS1,HNRNPL,VKORC1L1,TOM1L1,RABL3,YIPF3,SIGMAR1,KDELR1,CTLA4,VAPB,TMEM14B,CAV2,GNAQ,TSPAN3,ARL15,NKAPD1,TSPAN15,TMX2,BCL7B,SREK1IP1,TSPAN17,HSPA8,GPM6A,TMEM167B,SLC7A1,CMAS,TSPAN5 |
| 7.093e-04 | -7.25 | PRMT8 (protein arginine methyltransferase 8) | protein interactions | 56341 | 82 | 37 | 19454 | 5460 |
ERH,ACTB,TUBB,INA,ALYREF,TUBA1B,RSRC1,SYNCRIP,SERPINH1,DDX1,FBXW11,CHTOP,CIRBP,HNRNPA1,PIK3R1,RNF26,TIGD7,COIL,GRPEL1,THRAP3,HNRNPK,GIMAP2,ATAD1,DHX9,EWSR1,ZNF451,PML,RBM3,LSM14A,HNRNPH3,ZSCAN1,TNPO2,PRMT2,PPARA,EEF1A1,ATG16L1,UBL5 |
| 7.096e-04 | -7.25 | Protein ubiquitination | REACTOME pathways | R-HSA-8852135 | 62 | 32 | 10285 | 3229 |
UBE2N,UCHL3,RNF40,RNF181,BCL10,OTULIN,RNF152,UBE2K,CDC73,H2BC11,H2BC14,RRAGA,UBE2E3,UBE2H,SKIC8,UBE2W,H2BC17,H2BC12,UBE2B,USP5,UBE2D1,UBB,RPS27A,H2BC9,UBA52,UBE2D3,UBE2S,H2BC1,UBE2A,UBE2G2,UBE2L3,RNF20 |
| 7.098e-04 | -7.25 | CCDC140 (CCDC140 long non-coding RNA) | protein interactions | 151278 | 116 | 49 | 19454 | 5460 |
ZCCHC17,ACACA,ZNF770,RPLP0,RPL26L1,TFB1M,CCDC106,STAU1,RPL4,RPS15,MRPS7,BRIX1,RPL7A,RPF2,ZSCAN25,ZNF668,RPL26,FTSJ3,DCAF16,NSA2,ELAVL4,ZNF189,RPS3,ZNF22,RPS9,RPL13A,RPF1,RPL7L1,RPL19,TRMT1L,RBM34,LLPH,RPL18,RPL3,FBXO11,TRIM26,KRAS,RPL17,SRSF12,RPL6,RIOX2,RPL10A,RPL32,RPL8,HP1BP3,RPLP2,RPL7,RPS16,DKC1 |
| 7.098e-04 | -7.25 | Tmed2 (transmembrane p24 trafficking protein 2) | protein interactions | 56334 | 116 | 49 | 19454 | 5460 |
TMED4,NDUFB7,TMED5,ABCG2,SCFD1,CHCHD6,TRIM27,RRAS2,VAMP3,VDAC2,SLC35E1,RABL3,UBAC2,STOM,MMADHC,SDCBP,ATP2C1,TMUB1,TMED3,PHB2,ATAD1,GOSR1,PTDSS1,STOML2,TMEM199,NDUFB8,SLC2A1,ATP6V1A,CCDC127,NDUFB4,PHB1,STT3A,CAV1,SLC38A2,ERLIN1,NDUFS8,TMED9,ERLIN2,NDUFA2,NDUFA12,RPN1,CYBRD1,SLC39A7,TMED1,FLOT1,TMED7,RBCK1,VDAC1,B4GALT7 |
| 7.105e-04 | -7.25 | positive regulation of peptidase activity | biological process | GO:0010952 | 170 | 70 | 18204 | 5365 |
CYFIP2,RPS3,MIR15A,EGLN3,DAPK1,BAK1,CLEC7A,CTSK,MYC,BAX,MUL1,ROCK2,BOK,EPHA4,SMAD3,TNF,TNFSF10,ACVR1C,VSIR,EFNA3,APH1A,DDRGK1,TANK,FASLG,AGER,KHDC1,PYCARD,S100A8,NKX3-1,BCL10,HSPD1,AIFM1,CLDN4,TNFSF15,NLRP1,PSENEN,FAM162A,MIR205,SYK,PDCD5,HMGB1,NLRP2,BAD,DAP,NCSTN,CRADD,PMAIP1,PRELID1,BCL2A1,JAK2,SEMG2,BCL2L1,ARL6IP5,HSPE1,RPS27L,PSME2,CTSD,MIR21,FIS1,PPARG,CLDN3,IFI16,MCL1,PSME1,ANP32B,FAS,IFT57,NLRP3,MIR17,HTRA2 |
| 7.107e-04 | -7.25 | EPHB2 (EPH receptor B2) | protein interactions | 2048 | 211 | 81 | 19454 | 5460 |
NUDT19,STIM1,TAB2,HGS,SNAP29,EPHA4,KRAS,SRPRB,POLDIP3,ADD2,AHCYL1,SPSB1,SLC39A7,PICK1,EFNB1,MMP9,NCK1,BCL2L1,HMGA1,PIK3R1,CTNNB1,EIF2S1,ARF6,FCHO2,EPHB6,CAV1,TNIK,RAB35,HACD3,EHBP1,CDCA3,SEC23A,SDCBP,JUP,VAV2,SDC2,USE1,HECTD1,CLDN4,USP6NL,NOTCH2,NTPCR,CYFIP2,YKT6,NF2,PIK3R2,HSPA5,SEPTIN6,LIN7C,FOS,ARHGEF6,BANF1,HSPA8,STK26,HADHA,RHOB,EPHA2,RAB2A,NIBAN2,CSK,EPS8,FBXO7,RPS29,SLC1A3,GORASP2,GPX1,TRIM54,COPE,MB21D2,YES1,FERMT2,ROCK1,VIRMA,NCKAP1,EFNA5,SRC,VEGFA,VAMP3,GAB1,TUBA1B,MSN |
| 7.107e-04 | -7.25 | KPNA4 (karyopherin subunit alpha 4) | protein interactions | 3840 | 211 | 81 | 19454 | 5460 |
NFE2L2,EZH2,NUPR1,SMARCB1,MTA2,RANBP1,TP53,NUP153,ACTR1A,SOX2,CSE1L,KPNA2,NUP107,HUWE1,MNAT1,CCAR1,GTF3C3,MEPCE,CCT8,MEF2C,TRIM11,ACTR1B,PC,ZC3H11A,ARMC8,CDKN1B,AHSA1,CSNK2A1,CCT7,NCBP2,CTDSPL2,LDLR,RB1,ADNP,HSP90B1,IER2,GTF2IRD1,SOST,LMNA,PLAA,SUMO1,DMTF1,EEF1G,B2M,GTF2I,MBD3,TRIM3,FAM50B,PML,BAP1,RPA3,SQSTM1,NUP50,HSPA8,LMNB1,MECP2,CCT2,MAPRE1,COP1,STK11,NTRK3,CFAP20,HNRNPC,CUL3,MYC,MCM4,PPP1CC,SMARCE1,RBBP4,FBXO22,SEC63,DYRK1A,CBX5,MAT2B,POLR2B,RAN,UQCRC2,OPTN,CFAP298,UBE2I,PHAX |
| 7.131e-04 | -7.25 | PTPN6 (protein tyrosine phosphatase non-receptor type 6) | protein interactions | 5777 | 260 | 97 | 19454 | 5460 |
BRIX1,RPL4,RPL27,STAT6,PRKCA,CDK1,DUSP18,SRC,RPL22,RPL10L,RPL13A,TXN,PSMC5,EIF2S2,CDC73,IFNAR1,RPL26,RPS17,PTPN11,IL2RB,RPL7A,MPIG6B,RPF2,RIGI,RPL17,CTNND1,H3C1,IGF1R,RPL23A,NUDT16,RPL15,DDX39A,CDC5L,CAV1,CDK9,LCP2,RPL35A,ALYREF,RPL32,SRP14,TREML1,SMAD3,RPL12,PTPN1,RPL10A,CD247,SHC1,PSMD7,H2AC4,FCGR2B,CXCR4,LILRB1,DUSP22,IL6ST,SYK,RPL10,PRRC2A,RPL19,JAK2,RPL35,TRIM29,RPL7L1,PSMD4,RPL37A,CD79B,FAS,PSMD1,RPL39,TFG,RPL28,SRSF4,KIT,FHL3,JAK1,RPL18,GHR,ZRANB2,NME1,ACTN4,RPL29,MACROD1,RPL7,MAGED2,SRSF1,PTK7,LILRB4,RPL8,CBL,TRAF6,TLR10,SKIC8,SPATA2,CTNNB1,PTDSS1,RPL6,PIK3R1,PSMD3 |
| 7.134e-04 | -7.25 | cellular catabolic process | biological process | GO:0044248 | 778 | 270 | 18204 | 5365 |
MAP1LC3A,ACER3,HGS,IRF8,AKR1A1,HBM,VIPAS39,TSG101,PCSK9,ILVBL,NR1I2,PLA2G5,GAD2,RETREG3,HBB,TST,FIS1,PLAA,BECN1,TM9SF1,ATG4C,CYP2C8,CYP1A1,NRBF2,TOLLIP,EHHADH,VTA1,XBP1,BAG3,CTSK,CPT1B,GPX1,ACADS,FBXL4,CPT2,ANXA7,GPT,STBD1,DPEP1,HSD17B10,CRYL1,PCCB,GABARAP,VPS4B,GPC1,UBXN6,ADTRP,C9orf72,VPS39,FUNDC1,PTPN22,GDPD3,USP13,PEX13,ESD,PLA2G15,RAB1B,VAMP8,FMO1,AMACR,GSTM2,CHMP2B,CD36,RAB1A,TAX1BP1,PNPLA8,ASRGL1,PIM2,OPTN,SNAPIN,NUDT19,VPS18,NEU1,SMPD2,OXCT1,SLC25A17,TP53INP2,VTI1B,MCOLN1,PRDX4,CHMP2A,CRAT,PHYH,CRYZ,IDE,ENPEP,PSEN1,MTM1,HADH,ATG9A,ETFA,SRD5A3,PLPP6,CYP2D6,SMURF1,PLCB1,ATG7,PCK2,KLHL3,DNM2,ABHD12,MGST2,LIX1,LAMP2,ALDH1L1,ABHD6,TP53INP1,HEXA,PRDX3,AUH,CHMP1A,ACAA2,PLA2G4B,RGS19,CHAC2,FITM2,GSTM3,RAB23,TBC1D25,SUCLG2,HSP90AA1,SNAP29,ACADSB,WDR45,GPR137,GDE1,VPS33A,CYP26A1,DRAM1,MAP1LC3B,LDLR,OAT,TAFAZZIN,GPX3,ARG2,GGT7,ECHDC1,UBXN2B,DAP,PHF23,ATG3,MPST,SLC25A44,SH3GLB1,TMEM39A,CYP2C9,TMEM74,VPS54,AMT,RIMOC1,RETREG2,CAPN1,ACOT8,TMEM59,CTSD,RAB19,ACAT1,UFM1,MTHFS,HBE1,TBC1D17,GSTM4,CYP1B1,TBC1D5,TRAF6,VPS16,RAB2A,GLUL,VMP1,ABHD16B,RAB33B,SNX14,TEX264,RAB33A,VAMP7,SHMT1,GALC,ADIPOQ,ATG16L1,ATG4A,MCAT,DDRGK1,LGALS8,PPT1,S100A8,HDAC6,HSD17B6,PRDX6,TRIM5,STK11,CYP3A5,CYP4F12,MME,DDAH1,STUB1,CLU,HMGB1,NSFL1C,TMBIM6,SDS,CDK5,BCKDK,EMC6,VPS28,EI24,TRAPPC4,GABARAPL1,HEXB,PPM1K,AASDHPPT,GNPDA2,NFE2L2,FBXO7,HNMT,ABHD2,CBR3,ETFB,PNPLA4,CYP27B1,FGF23,CHMP4C,RETREG1,STX17,UFL1,SLC16A1,ACOX1,IFI16,RAB39B,FUNDC2,CRYM,NUDT7,CDO1,GNPDA1,GABARAPL2,FAH,TMEM208,CHMP5,GSTO1,STX12,SESN2,LYPLA2,GPIHBP1,HBA1,ATG101,USP30,DBT,TOM1,DLST,DECR2,VPS4A,HADHA,TP53,MAP1S,IDO1,AIG1,PHB2,EVA1A,RNF41,LEP,SQSTM1,TFEB,SORD,RB1CC1,UGT1A1,PRDX2,SLC25A21,PRDX1,HSPA8,CHMP1B,SRC |
| 7.135e-04 | -7.25 | CHMP2B (charged multivesicular body protein 2B) | protein interactions | 25978 | 71 | 33 | 19454 | 5460 |
CHMP1A,CHMP4C,TRIM36,PAFAH1B1,KBTBD4,CFTR,SEC62,TRAF2,USP8,STAU1,FKBP8,STX7,CHMP2B,VTA1,TMEM106B,BAP1,SQSTM1,RAB5C,DPY30,FBXO7,XPO1,COPS5,BTF3,ACTB,CGAS,CHMP5,ZBTB2,ATP6AP2,CHMP2A,ESR2,MALSU1,MAD2L1,PNMA1 |
| 7.139e-04 | -7.24 | chloride channel inhibitor activity | molecular function | GO:0019869 | 6 | 6 | 18094 | 5411 |
STX8,STX7,STX1A,VAMP8,VTI1B,CFTR |
| 7.165e-04 | -7.24 | PPP2R1B (protein phosphatase 2 scaffold subunit Abeta) | protein interactions | 5519 | 157 | 63 | 19454 | 5460 |
PDCD4,COP1,FBXW11,STK24,MCM3,RAB11A,FGFR1OP2,TNFAIP3,CSK,JAK2,CTTNBP2NL,DYNLL1,DAPK1,PRDX2,RALA,POLR2F,PPP2R5E,FAM43A,CSNK2B,MOB4,TBCCD1,BAD,SLC25A3,IER2,FGFR1,CDK1,FOXS1,CFTR,SYK,PPP2R3A,PPP2R2C,STK26,HSPA8,CRY1,SERTAD2,FBXW4,PDCD10,NPSR1,PPP2R5A,PRDX1,CEP19,CAV1,SLMAP,EGLN3,TOP1,TRIM35,HNRNPL,SPPL3,PPP2CB,TRAF3IP3,PPP4C,RPN1,EEF2,PPP2R1A,CDK4,SUPT5H,MAX,SSRP1,RAB18,SERTAD1,SIKE1,HSPD1,TFPT |
| 7.212e-04 | -7.23 | PTPN14 (protein tyrosine phosphatase non-receptor type 14) | protein interactions | 5784 | 160 | 64 | 19454 | 5460 |
CRLF3,LAMTOR1,RHOB,BICD2,RC3H2,YWHAZ,MYC,SFN,CUL3,CUL2,DNAJC5,BAG3,RHOJ,VIRMA,CTNNA1,PTEN,JUP,RPA2,WWP1,HECTD1,INPP5E,ATG16L1,SIPA1L1,CDC42,RANBP10,STX7,RTKN,HAX1,ARMC8,YWHAB,ANKRD50,WWP2,SAV1,YWHAH,YWHAG,CTNNB1,KCTD3,SPPL3,FZR1,ARF6,STK3,CAV1,RAB35,EIF4E2,GJA1,KRT8,CTNNA2,BPIFB1,VPS33A,RND3,MOB3C,RAF1,JPH4,PPP2R1A,KIF2A,KRAS,SRSF12,FLOT1,COPS4,AHCYL1,HSPD1,ZYX,MAEA,TESK2 |
| 7.212e-04 | -7.23 | leukocyte proliferation | biological process | GO:0070661 | 153 | 64 | 18204 | 5365 |
CD40,LILRB1,HSPD1,BCL6,FOXP3,PRDX2,RAC2,JUNB,CLU,SASH3,TLR4,CD40LG,PELI1,PIK3CG,TNFSF18,IFNA13,TP53,IL12B,IL10,CX3CL1,IDO1,LMBR1L,CCND3,SELENOK,IFNA10,AZI2,GPAM,BAX,KIT,ALKBH5,NDP,NDFIP1,PRKCQ,PSMB10,EMP2,IL20RB,CD38,IFNK,HELLS,GJA1,MSN,DLG1,IFNA2,TBK1,EFNB1,IL2,LIPA,GAPT,RC3H2,IL34,TICAM1,CD151,IFNB1,IL15,BCL2L1,IL2RA,IL7,MEF2C,NCSTN,CD28,FOSL2,BAP1,IL23A,FKBP1B |
| 7.212e-04 | -7.23 | myeloid leukocyte differentiation | biological process | GO:0002573 | 153 | 64 | 18204 | 5365 |
RBPJ,SNX10,IFNG,CLPB,GLO1,TNF,UCP2,PAFAH1B1,NOTCH2,FOXP1,JAGN1,TFRC,CDC42,MMP9,TF,SFRP1,CREB1,CTNNB1,MITF,FAM20C,LARGE1,PIR,EPHA2,CEBPE,JUNB,NKAP,LBR,BATF,TLR4,ITGB8,CCR7,CSF2,FOS,TYROBP,IL15,SRP54,PDE1B,IREB2,VEGFA,FOSL2,BAP1,TOB2,KIT,NDP,IL4,TLR2,TCTA,MYD88,TRAF6,RUNX1,DHRS7B,PIK3R1,PSEN1,STAT5A,OSTM1,CD81,CD4,LTBR,CCL19,PPARG,TGFBR2,IRF4,VPS54,IFI16 |
| 7.221e-04 | -7.23 | SNX2 (sorting nexin 2) | protein interactions | 6643 | 202 | 78 | 19454 | 5460 |
GNAO1,CSNK2B,GSK3A,SFXN2,CTTN,DUSP10,ESR2,MTM1,STAT1,SNX3,TSN,PPAT,RNF40,DNAJC5,NIBAN2,CSK,CABCOCO1,RAB11A,KLHL1,FAM221A,DNAJB6,SNX5,LAMTOR1,SDF2L1,CYP1A1,RAB9A,RTN4,RAB5A,PMAIP1,BAP1,RPA3,STX7,BORCS6,ATP6V1C1,SHMT1,LEPR,MET,VAPB,RPA2,FGFR1,CYB5A,USP46,RAB35,STX6,EGLN3,CDC5L,HNRNPL,ARF6,SNX2,RHOH,KCTD10,SNX1,YWHAG,ATG7,COPS5,YWHAH,LAMP3,TBC1D5,SPATA2,HENMT1,ATG9A,LAMP2,VPS26A,RAB5C,PDAP1,RHOG,RUVBL2,IGF1R,VPS26B,YIF1A,PAK6,SAR1B,KRAS,ACVR1B,TP53,HGS,TFRC,RAB4A |
| 7.251e-04 | -7.23 | NAA10 (N-alpha-acetyltransferase 10, NatA catalytic subunit) | protein interactions | 8260 | 163 | 65 | 19454 | 5460 |
PSME2,KRT8,HYPK,PLSCR3,NAT2,WIF1,EGLN3,NAA11,CIAO3,VPS26A,YWHAH,YWHAG,PPM1B,SSX2IP,PSME1,MRPS11,BAALC,ABCE1,ZBTB14,RBCK1,TTC4,HNRNPK,KRAS,TFG,CAPZA1,TBK1,NAA15,NAA16,TULP3,AZI2,CAPZA2,PDHA1,POLR2C,DLST,OPTN,ZNF655,STAT1,NMI,TNPO3,CREB3,NAA50,SAMHD1,TSEN54,RIT1,DNAJB6,UBE2H,OSGEP,CCDC174,INPPL1,RPA3,RBM23,BAP1,DLAT,CCDC106,SNX33,HSPA8,PGK1,FBXW7,GTF2I,CMAS,DDIT4L,CFTR,CCNH,RPA2,UBE2M |
| 7.251e-04 | -7.23 | ANK3 (ankyrin 3) | protein interactions | 288 | 163 | 65 | 19454 | 5460 |
CTNNB1,PPFIBP1,PIK3R1,USP15,NAB2,TIAM1,AGR2,RHOG,GJA1,MAP1LC3A,FEZ1,SMAD3,RAB35,CAV1,DIRAS3,STX6,SPTAN1,FCHO2,ARF6,HNRNPL,GABARAPL1,MAP1LC3B,TP53,E2F4,RAF1,NAA35,RND3,KCNC1,PCNA,PQBP1,PALM2AKAP2,FLOT1,CTNND1,MCM6,FGF12,H3C1,KRAS,MCM4,DNAJC5,ARHGAP21,BTF3,CUL3,SMAD2,NTRK3,RHOB,IVNS1ABP,H1-10,FAS,CTNNA1,DOK4,CCNF,UQCRC2,SRPK2,FBXO22,RAPGEF5,CDC42,GTF3C4,SPTBN1,ATG16L1,FGFR1,SCN1B,RHOU,BAP1,GABARAP,STX7 |
| 7.307e-04 | -7.22 | small molecule biosynthetic process | biological process | GO:0044283 | 459 | 167 | 18204 | 5365 |
ACAA2,DECR2,LEPR,G6PC3,SEPHS2,PTGES,SLC25A1,DEGS1,CYP39A1,NANP,PGM1,IDO1,SERINC3,ADK,HACD2,UBIAD1,ELOVL3,ACCS,CYP27A1,FBP2,SPR,FADS2,ENO2,PPARA,SORD,UGDH,ATF4,INSIG2,LEP,SLC1A3,HSD17B8,SPTSSB,IP6K1,UST,IMPA2,SCD5,ENO1,SLC37A4,OAT,ACSS2,GGTA1,ERRFI1,PTGES3,MTHFD2L,PDSS2,MIF,PNP,ISYNA1,NDUFAB1,NUS1,AASDHPPT,PRKAG1,MGST3,SLC38A1,HMGCS1,PNPLA8,SLC25A11,PYCR1,CYP27B1,HACD1,ELOVL7,ABHD2,PC,PTS,MOXD1,COQ8B,PTGDS,SLC19A2,DTYMK,SRD5A3,PLPP6,SC5D,PGK1,NSDHL,ELOVL4,CYP7A1,LIPA,ASNSD1,MDH1,MGST2,MTAP,SLC25A12,BRCA1,HACD3,PCK2,CYP2D6,CDO1,PRKAB1,PRPS1,LIAS,FA2H,CYP2R1,GLUL,GSTP1,DBH,UCKL1,CRTC2,HSD17B10,NPC1L1,COQ10B,OSBP,CYP11B2,PCBD1,CYB5R3,MCAT,SHMT1,LHB,PYCARD,LBR,HACD4,ATF3,AKR1B1,FBP1,PYCR2,MSMO1,AMACR,PGAM1,SEPHS1,FMO1,GSTM2,SDS,QNG1,SYK,CYP11B1,GGT7,PLP1,HSD17B3,ALOX5AP,ELOVL1,ACACA,FDFT1,SLC25A10,AKR1A1,CRY1,RDH10,SPTSSA,THTPA,SLC19A3,ACER3,SPHK2,CBR4,CYP2C9,ELOVL6,HPGDS,ILVBL,DCTD,PLA2G5,DNPH1,GAD2,MECR,CYP1A1,HSD17B1,MVD,CYP2C8,ACOT8,ALDH1A3,GAMT,G6PD,TECR,FMO3,CFTR,GSTM4,XBP1,GPX4,PNPO,RGN,COQ8A |
| 7.309e-04 | -7.22 | PEX3 (peroxisomal biogenesis factor 3) | protein interactions | 8504 | 169 | 67 | 19454 | 5460 |
VIPR1,AKAP1,MAVS,DERL1,EXD2,PXMP2,YKT6,HSCB,TIMMDC1,PRKCA,CTDSP1,LMNA,RPA2,UBAC2,RPS9,SLC1A1,ARF1,CDIPT,UQCRC2,TECR,APLNR,SLC25A1,RPL7A,FIS1,SERPINH1,CHCHD4,RPL3,CLPB,LRRN4CL,SLC25A10,SLC25A11,NKRF,RPS4X,FASTKD5,FKBP8,HNRNPF,USP30,HUWE1,TMEM33,VRK1,TGFBR2,MTARC2,FAF2,MGARP,CYB5B,RPN1,SURF4,AQP3,DSTN,STX5,PTPN1,AIFM1,PHB1,RAMP3,DUOXA2,DHX15,PEX13,PPIB,XPO1,CALR,PSMD3,FAR2,MARCHF5,AKAP8L,CDC23,SLC2A1,TUBG1 |
| 7.309e-04 | -7.22 | EP400 (E1A binding protein p400) | protein interactions | 57634 | 169 | 67 | 19454 | 5460 |
CSGALNACT1,PDCD4,AR,NTAQ1,MORF4L1,MYC,HNF1B,APEX1,VIRMA,ACTB,SNRNP40,TUBB,TRIM29,STAT2,CSNK2B,VPS72,ELK3,PLAC1,MED23,KLF3,RPA2,KLF12,ING5,ACTL6A,FBXW7,KDM1A,MNS1,PML,FOS,RPA3,LHX2,POU5F1,KPNA1,H2AC4,ACTL6B,CTNNB1,ZMYND11,DYRK1B,SUMO2,TOP1,MEAF6,EED,PPP2CB,H2AZ1,TBC1D4,H2BC1,CBX3,DMAP1,EZH2,SOX9,ELF1,PPP2R1A,EGR2,CD2BP2,TRAF2,SOX2,SUPT5H,TP53,TOP3B,RAF1,MAX,PAX6,ASF1A,RUVBL1,KRAS,RBBP7,RUVBL2 |
| 7.313e-04 | -7.22 | regulation of tyrosine phosphorylation of STAT protein | biological process | GO:0042509 | 76 | 36 | 18204 | 5365 |
IFNG,CNOT7,OSBP,IL12B,ARL2BP,CAV1,IL15,TNF,CCL5,HCLS1,EPO,SOCS3,JAK2,IGF1,IL3,IL13,NF2,IL21,IL6,GH1,IL23A,OSM,CD40,IL4,KIT,IL12A,GHR,IL18,CSH1,LEP,MIR146A,TNFSF18,IL2,MIR221,IL6ST,CSF2 |
| 7.328e-04 | -7.22 | XPO7 (exportin 7) | protein interactions | 23039 | 172 | 68 | 19454 | 5460 |
LMBR1L,SCN2B,RAN,CHRM4,ENO1,ZNF330,CTNNA1,UBE2I,TMEM108,TAB1,APLNR,DYRK1A,VIRMA,ESR2,CARS1,OPRM1,CIAO1,GPR17,CUL3,SAMHD1,USP14,COMMD9,CCDC22,TRIM23,BICD2,XPOT,UBE2H,SLC39A9,PPM1G,RPA3,SIRT7,TTC1,AKAP1,NPTN,RP2,COIL,NUP62,FAM234A,HCST,RPA2,EIF4B,HRAS,CD274,SEC23A,ARL4D,HNRNPL,VPS26C,OSBP,PTP4A3,G6PD,MOV10,XPO1,DLK2,FXYD6,PDCD1,PEX3,FAF1,NUP107,RBBP7,CD80,SEPHS1,COMTD1,RANBP1,NUP153,GFPT1,JUN,SH3GLB1,CYB5B |
| 7.331e-04 | -7.22 | positive regulation of phosphorus metabolic process | biological process | GO:0010562 | 697 | 244 | 18204 | 5365 |
PIK3R3,MAP2K3,CHP1,TGFB2,OSBP,IGF1,KRAS,PDCD10,MT3,TF,CCND3,NCK1,FGF10,GH1,TXN,AKT1,TNFSF15,BTBD10,IL1B,RAP2B,ADTRP,TNFSF18,PROX1,ADRB2,GREM1,SLCO3A1,IFNA13,TLR6,CCR7,FGF1,NRP1,IL5,JAK2,MMD,FCGR1A,BAD,DVL2,MAP2K1,GSK3A,FAS,SOX9,KIT,PID1,ODAM,LMO4,MET,DIRAS2,CARTPT,AR,DLG3,CRKL,CCND1,MIR221,PAK2,TGFBR2,IL2,EPHA4,TLR3,UBE2K,IL12B,CCL5,CD86,MMP9,PPIA,IFNA10,DUSP19,ERP29,FERMT2,MOB3B,IL6,TOM1L1,IGF1R,ENO1,HTR2A,BCL10,IL12A,TPD52L1,PPP1R12A,MIF,PSRC1,PPARA,FLOT1,VEGFC,CSF2,HAX1,IL6ST,PRNP,CLIP3,MAP3K12,HSP90AA1,TAB1,MAVS,CLEC6A,DSTYK,MAD2L2,SMYD3,IFNB1,CAV1,MEF2C,EFNA5,PRKAG1,UCN,CD80,AGAP2,HSP90AB1,CD36,PPP2R5A,RGCC,NPTN,IL4,CREBL2,IFNK,MOB3C,HDAC3,EMP2,CD4,MIR21,MIR30B,IFNA2,TNIK,HBEGF,PSEN1,EHD4,LCP2,CX3CL1,RAF1,ROCK2,WEE2,FGF3,DDRGK1,MAP3K11,TNF,ADIPOQ,FGF17,PHB1,YES1,TFRC,TRIM6,LACRT,RPS3,AVPR1B,CX3CR1,TRAF2,RAP1A,RALB,EPHA2,CD40,SYK,FGF16,FGF7,AGER,STK11,HRAS,FBXW7,NKX3-1,CAB39,PRR5L,HDAC6,ARL2BP,TMSB4X,CDKN1A,ZNF622,MAP2K6,PSMD10,TNFRSF14,HCLS1,CHI3L1,ADNP,STRADB,ILK,TESK1,TAFAZZIN,PIH1D1,RARRES2,TRAF6,ACVR1,DDR1,TBK1,XRCC5,CLDN3,CCL19,DIRAS1,F2,STK4,TAB2,TP53,TCIM,NTF4,SPPL3,IFNG,SDCBP,CCNY,DIPK2A,CAMP,LEPR,IL13,KCTD20,ROCK1,CACUL1,ITGA6,IL21,FGF22,PTPN1,GHR,ADORA1,SRC,RAP2C,ANGPT1,P2RY1,FGFR1,PTGES3,CSH1,RB1CC1,IL18,MIR26B,PIK3CG,TLR4,APLNR,DLG4,LEP,SQSTM1,PHB2,PTPN11,FGF23,IL34,APOC2,EPO,IL15,CHRNA7,IL3,EZH2,IL23A,SEMA7A,VEGFA,GPNMB,FAXDC2,OSM,RAP2A,CDKN1B,NBN,CAMK1,NTRK3,NTRK2,CAPN2 |
| 7.331e-04 | -7.22 | positive regulation of phosphate metabolic process | biological process | GO:0045937 | 697 | 244 | 18204 | 5365 |
FBXW7,NKX3-1,PRR5L,CAB39,HDAC6,STK11,AGER,HRAS,SYK,FGF16,FGF7,RALB,EPHA2,CD40,AVPR1B,RAP1A,TRAF2,CX3CR1,PHB1,TFRC,YES1,TRIM6,LACRT,RPS3,FGF3,MAP3K11,DDRGK1,ADIPOQ,TNF,FGF17,CX3CL1,RAF1,ROCK2,WEE2,CLDN3,CCL19,F2,DIRAS1,TBK1,XRCC5,DDR1,RARRES2,TRAF6,ACVR1,ILK,TESK1,TAFAZZIN,PIH1D1,ADNP,STRADB,PSMD10,MAP2K6,TNFRSF14,HCLS1,CHI3L1,ARL2BP,TMSB4X,CDKN1A,ZNF622,PHB2,PTPN11,PIK3CG,APLNR,TLR4,DLG4,LEP,SQSTM1,P2RY1,FGFR1,PTGES3,CSH1,RB1CC1,IL18,MIR26B,FGF22,PTPN1,GHR,SRC,ADORA1,RAP2C,ANGPT1,ROCK1,KCTD20,CACUL1,ITGA6,IL21,CAMP,LEPR,IL13,SDCBP,CCNY,DIPK2A,STK4,TP53,TAB2,TCIM,NTF4,IFNG,SPPL3,NTRK3,NTRK2,CAPN2,NBN,CAMK1,RAP2A,CDKN1B,GPNMB,FAXDC2,OSM,IL23A,VEGFA,SEMA7A,CHRNA7,IL3,EZH2,EPO,IL15,IL34,FGF23,APOC2,SLCO3A1,IFNA13,CCR7,TLR6,ADTRP,TNFSF18,PROX1,ADRB2,GREM1,RAP2B,AKT1,TNFSF15,BTBD10,IL1B,FGF10,GH1,TXN,MT3,TF,CCND3,NCK1,IGF1,KRAS,PDCD10,PIK3R3,MAP2K3,TGFB2,CHP1,OSBP,CCND1,PAK2,MIR221,TGFBR2,IL2,DIRAS2,CARTPT,AR,DLG3,CRKL,ODAM,MET,LMO4,FAS,KIT,SOX9,PID1,DVL2,MAP2K1,GSK3A,FCGR1A,BAD,IL5,JAK2,MMD,FGF1,NRP1,CSF2,HAX1,IL6ST,PRNP,CLIP3,MAP3K12,HSP90AA1,PPARA,FLOT1,VEGFC,PPP1R12A,MIF,PSRC1,BCL10,ENO1,HTR2A,IL12A,TPD52L1,ERP29,FERMT2,IL6,MOB3B,TOM1L1,IGF1R,CD86,PPIA,MMP9,IFNA10,DUSP19,CCL5,TLR3,EPHA4,UBE2K,IL12B,EHD4,LCP2,MIR30B,MIR21,IFNA2,CD4,HBEGF,TNIK,PSEN1,IFNK,MOB3C,HDAC3,EMP2,PPP2R5A,RGCC,NPTN,IL4,CREBL2,UCN,CD80,AGAP2,HSP90AB1,CD36,MEF2C,EFNA5,PRKAG1,MAD2L2,SMYD3,IFNB1,CAV1,TAB1,MAVS,CLEC6A,DSTYK |
| 7.340e-04 | -7.22 | RANBP1 (RAN binding protein 1) | protein interactions | 5902 | 175 | 69 | 19454 | 5460 |
HNRNPC,CUL3,MYC,RAB2A,BTF3,LMNB1,UBE2H,PSMA6,RAN,DLST,CTNNA1,UBE2I,SUMO1,EEF1E1,NUP62,CDK7,NEK7,CFTR,MRPL10,ARMCX3,LMNA,RPA2,MYL6,UBE2M,HIRA,BAP1,RPA3,MTDH,NUP50,HSPA8,FBXW7,UFL1,EMC1,HSPA5,KARS1,IFI16,DDRGK1,MPG,CTNNB1,XPO1,MRPL9,ATP6V1D,DCK,SUMO3,RANGRF,G6PD,NUP35,EGLN3,MDM2,INSIG2,IPO8,NUP37,TNPO2,NUP153,ACTR2,PLS3,EZH2,NUPR1,RAB1A,IDH1,EWSR1,SCPEP1,TOLLIP,NUP42,KRAS,G3BP1,NUP107,FLOT1,TUSC3 |
| 7.340e-04 | -7.22 | ATL3 (atlastin GTPase 3) | protein interactions | 25923 | 175 | 69 | 19454 | 5460 |
FASTKD5,RIGI,ZNF609,TSSC4,CD80,SRPRB,MAP1B,RAB1A,TCOF1,CCR1,MOB3C,BIRC5,MGARP,ISG15,LPAR6,GDE1,UBL5,TBK1,ETFB,MARCHF4,EEF1B2,PHB1,YWHAB,USP15,POR,ESYT1,LAMP3,H2AC14,FAM20C,EMC4,EDEM1,RAB5C,TACR3,NRBF2,SLC5A6,RNF5,MRPL40,PHB2,GRPR,EEF1G,ATP5F1E,VIPR1,SYVN1,HSPA8,RTN4,HADHA,ARCN1,SLC22A8,VAPB,CDC42,HCST,RGL1,RND2,RABL3,ATP6V1C1,SEC22B,PGRMC1,APLNR,VIRMA,COPE,CAVIN2,RAB14,REEP4,ATL1,SNX14,ATP5F1A,OST4,MYC,GPR17 |
| 7.366e-04 | -7.21 | negative regulation of phosphate metabolic process | biological process | GO:0045936 | 377 | 140 | 18204 | 5365 |
STAP1,DUSP10,STK38,GRB10,PKIA,C9orf72,PYCARD,DDIT4,PRR5L,FBP1,HEXIM2,RGS2,IL1B,AKT1,DKK1,PTPN22,DNAJC10,CORO1C,DUSP1,NCK1,PPP1R1B,SPRED2,BAK1,HYAL2,GSTP1,CDKN2C,DUSP22,ROCK2,DUSP3,MIR675,CHP1,MIR24-1,ADIPOQ,TNF,SPRED1,CAMK2N1,DBNDD1,CRKL,TRIB1,SLC8A1,TRIM63,FIS1,PAK2,IL2,CTDSP1,PID1,CBL,CAMK2N2,GADD45A,MIR20A,YWHAB,RGN,GSKIP,RB1,ADNP,DEFB114,PPP1R8,CDK5RAP3,TESK1,CDKN1A,MACROH2A1,LRP6,PKIB,FKBP1A,DUSP6,PTEN,TSG101,PARD6A,TRIM27,PPARA,THY1,CTDSP2,HEXIM1,SPRY1,SOCS4,PRNP,ZBED3,ERRFI1,ANGPT1,INPP5K,MIR132,PTPN1,PTPRQ,HSPB1,NUPR1,PRDX3,DUSP19,MIR15A,PPIA,MIR34A,GNAQ,RTRAF,IER3,FLCN,SFRP1,ROCK1,PDCD4,BAX,TP53,FKBP8,IFNG,TAF7,YWHAG,DYNLL1,MIR106B,MIR146A,PSEN1,PAQR3,DNAJC3,LILRB4,ARPP19,INHA,PPARG,IGFBP3,SFN,MIR212,MIR218-1,NTRK3,PGR,MIR711,PPP2R5A,CNKSR3,CDKN1B,SOCS5,IMPACT,TSPO,PKIG,UBASH3B,CAV3,NF2,CEP85,CDKN2D,SWAP70,FKBP1B,IKBKB,MIR137,SOCS3,PAX6,CAV1,LGALS3 |
| 7.367e-04 | -7.21 | preribosome | cellular component | GO:0030684 | 107 | 47 | 19108 | 5553 |
RPS4X,PNO1,NOB1,FCF1,NOP9,SRFBP1,IMP4,RRP7A,WDR3,XRCC5,UTP25,RPS27A,RPS9,NGDN,RPS11,KRR1,RIOK2,PWP2,RPS28,RPS23,NOC4L,AATF,UTP6,IMP3,UTP15,MAK16,RPS7,RCL1,RPS14,ZNF622,PPAN,RPS12,UTP23,RPS16,EMG1,WDR12,RPS5,NOL7,NSA2,NOP58,MPHOSPH10,RPF1,RPS24,RPS13,FTSJ3,RPS17,MRTO4 |
| 7.380e-04 | -7.21 | ACKR3 (atypical chemokine receptor 3) | protein interactions | 57007 | 18 | 12 | 19454 | 5460 |
GJB2,TP53,UBR7,ATP5F1A,ATP5F1D,HNRNPL,ATP5PO,ATP5F1B,ESR2,HEXIM1,MEPCE,ATP5PD |
| 7.380e-04 | -7.21 | COX7B (cytochrome c oxidase subunit 7B) | protein interactions | 1349 | 18 | 12 | 19454 | 5460 |
AUH,CTNNB1,COX6C,SMDT1,CYC1,NDUFB5,COX4I1,COX8A,KRAS,CYFIP2,HSCB,GNMT |
| 7.380e-04 | -7.21 | TLR5 (toll like receptor 5) | protein interactions | 7100 | 18 | 12 | 19454 | 5460 |
MYD88,TLR4,TMX2,MAN1A2,TLR1,TP53,DHRS7,DDRGK1,CNPY3,PTRH2,SNX14,DHRS3 |
| 7.382e-04 | -7.21 | PRKACG (protein kinase cAMP-activated catalytic subunit gamma) | protein interactions | 5568 | 99 | 43 | 19454 | 5460 |
MAGED2,TBCCD1,AIP,STUB1,UBB,PPP5C,CACYBP,HSP90AB1,CCT7,TTC9C,CDK17,DYNLL1,TCP1,PRKACB,ST13,HMGA1,MLF1,CUL3,HSP90AA1,HAX1,AKAP8L,DNAJC7,DNAJB6,PFDN6,PELI3,CCT2,CIRBP,FKBP4,HSPA8,RPAP3,CLPB,AKAP14,AKAP1,RLIM,CCT8,TIMP3,FKBP8,PTGES3,NUCKS1,PKIG,CCT5,PIH1D1,VAPB |
| 7.382e-04 | -7.21 | GCD7 (translation initiation factor eIF2B subunit beta) | protein interactions | 850998 | 99 | 43 | 19454 | 5460 |
RPE,THAP1,GKAP1,MX1,PTS,KLHL12,HGS,NME1,PAK5,RTN4,BIRC2,RABAC1,TIFA,S100B,DVL2,GNMT,COIL,DCTPP1,TOLLIP,RPIA,ZBED1,PCBD1,CEP70,NTAQ1,HNRNPC,TRIM32,KXD1,SORD,REEP6,SSX2IP,CDC23,MED4,RBBP8,UBE2I,TRIM27,HOMER3,PDE9A,STUB1,HSBP1,MIF,PLSCR3,GSTA4,SIAH1 |
| 7.382e-04 | -7.21 | PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1) | protein interactions | 5635 | 99 | 43 | 19454 | 5460 |
KBTBD4,UBLCP1,ELK4,CDC42,CD2BP2,CAV2,PRKCA,DDX5,MTDH,RAB5A,PRPSAP1,FBXW7,UFL1,HSPA5,RIGI,PRPS1,EMC4,FAM174A,SYNJ2BP,IFI16,XPO1,COPS5,FBXW11,IVNS1ABP,NCK1,FGR,ILK,UBE2H,USP15,SMG9,FBXO32,PHB1,CCNF,S100A6,UBE2I,PRKRA,RPL35,MAGOHB,PLEKHF2,CAV1,PTP4A3,SH3BGRL,HOMER1 |
| 7.382e-04 | -7.21 | PSME3IP1 (proteasome activator subunit 3 interacting protein 1) | protein interactions | 80011 | 99 | 43 | 19454 | 5460 |
PSMD4,TP53TG5,RPP25,PSMA6,CDR2L,SCNM1,PSMB4,CREB1,AVPI1,PSMB1,ZMAT5,HTRA2,PSMG3,PSMD3,PSMB2,MOV10,CSNK2A1,YWHAH,RASL10B,PSMA1,PSMA5,RAB40AL,PML,AMACR,NDUFB5,RPA3,TERT,NUP50,EWSR1,FOXS1,PSMB7,MRPS34,LMNA,CCDC69,ACACA,RPS11,PSMB3,IMP3,RPL15,RPP21,PSMB9,TRAF2,FBXL19 |
| 7.382e-04 | -7.21 | GPAT3 (glycerol-3-phosphate acyltransferase 3) | protein interactions | 84803 | 99 | 43 | 19454 | 5460 |
CXCR4,TSPAN15,TMT1A,VIPR1,TSPAN17,DERL1,RAB9A,RAB3B,PXMP2,DNAJC25,OTULINL,HCST,SEC62,KLRD1,ST7,RPA2,STIM1,RPN1,SSR1,GPR35,PTPN1,CCNF,HRAS,RAB35,PHB1,HSD17B11,EDNRA,SEC61B,DNAJC1,ARF6,LMAN1,TMPO,CHP1,SEC63,LAMP2,RAB5C,TSPAN10,SLC25A46,CIAO1,LAMP3,SLC2A1,ESYT1,TYROBP |
| 7.399e-04 | -7.21 | T_SNARE | prosite domains | PS50192 | 25 | 15 | 12186 | 3388 |
BET1,STX6,STX8,STX1A,STX11,STX12,STX7,STX17,SNAP29,STX5,SNAP23,BET1L,STX10,STX16,SNAP25 |
| 7.419e-04 | -7.21 | perinuclear region of cytoplasm | cellular component | GO:0048471 | 735 | 253 | 19108 | 5553 |
MX1,ACHE,CNP,WDR44,PICK1,RNF128,EIF2AK2,KCNS1,RAB3B,RNF41,TRAF6,DISC1,CCR2,HDAC6,CTLA4,TLR4,EHD3,RANGRF,HFE,VAMP3,CLIC4,PRKCE,ACTL9,STMN2,HCRT,TMEM100,CDH13,CX3CR1,TPD52,AZIN2,STX16,EXOC8,NUPR1,SNX5,LPXN,ANXA4,MAEL,VAMP2,TFRC,DCUN1D3,PTGDS,MYO6,LRAT,AQP2,RAB3C,TNFSF12,DLG1,CCDC42,HSP90AA1,CCIN,MRFAP1,VTI1B,NHERF1,AIFM1,GDPD3,GAPDH,SNAP25,SRFBP1,CAV2,KCNB1,MYO1B,GGPS1,CCAR1,ATRAID,PRKCA,EXOC1,RAP1A,EIF3G,ITGA2,TRMT112,YWHAB,PICALM,STX7,SLC11A2,GALNT1,PTPN22,HECTD3,PRDX6,CDKN1A,RAB14,TSNAX,RASGRP3,CD34,MSN,GALNT4,CASC3,CAPN2,RAB8B,PLEKHF1,MTDH,TOLLIP,AFTPH,VAMP8,CAV1,CHGA,PLN,SNCG,SPMIP6,AGGF1,ATXN10,STOM,MAP1S,INPP5K,HSP90B1,FBXW7,PDE2A,NME2,EXOC3,TF,GJB2,TRIM68,IGF2BP1,SLC30A7,PPIB,SLC1A3,CYFIP2,EHD1,STK16,EMP2,UNC45A,MLF1,S100B,ALG2,MT3,STX6,VAMP5,DCTN3,CYB5R4,VPS33A,TAF10,HYAL2,FAM168B,MTMR2,NOS1AP,FKBP4,CX3CL1,STX8,PRKRA,SRC,RAB1B,KLHL7,OSBP,PLSCR1,NXT2,SEC23A,SLC39A13,CRBN,MAD2L1,DAAM1,BRI3,EIF4A2,TRAPPC2L,PCLAF,MAP1B,MOB4,TPPP3,PAFAH1B1,PLAAT3,HRAS,LCP1,DDX4,PTGES,AANAT,DYNC1I1,COPS5,SNAPIN,NTRK2,NF2,CTNNB1,OPTN,SERINC3,FAF1,BUD23,ARFGEF1,STAT1,SELENOM,EIF4H,GAD2,TNKS2,VPS4A,STXBP1,ARHGAP1,RAB3A,USP2,PDE9A,STBD1,HSPA8,LAMP3,RAB29,PCSK9,MOSPD1,DICER1,CDK5R1,MTPN,SYNRG,AQP11,PKP4,SYT4,SPP1,PIK3CA,MLC1,DNAJB6,CDK7,RASD1,TPPP,SYP,CBL,EIF4E,MIR214,BCL10,TRIM37,ANP32A,MIR223,CLU,ACTN4,REP15,CALR,CTSB,STK26,EHD4,TESK1,NMRAL1,AIF1,UGT1A1,GALNT2,NDFIP1,PDE4B,CIDEB,HSP90AB1,MGAT1,RAB4A,TPD52L1,MTMR6,CHI3L1,MCM3,FASLG,VPS54,CCNF,SLC39A9,RTRAF,PIK3R1,S100A6,PDE7A,TNFRSF1B,APEX1,CDKN3,THBS3,STX10,UBE2I,MOBP,PDE8A,PAK2,PDLIM4 |
| 7.436e-04 | -7.20 | EZR (ezrin) | protein interactions | 7430 | 526 | 181 | 19454 | 5460 |
GDI2,EZH2,WDR37,ACTN4,MAPK10,ARFGAP1,TPD52,LASP1,SLC25A5,PDCD10,HNRNPD,ICAM2,PIK3R1,WDR44,SPTAN1,OCRL,INA,KRT8,PHB1,HEXB,SKA2,EMC9,TIMM13,NOTCH2,PRKAB1,LZTFL1,UCHL3,CYFIP2,PMAIP1,COMMD2,MYO6,BRCA1,FAS,CUL3,TXNRD2,NIBAN2,CLIC4,PTPRQ,SELL,ACTB,TAB1,MB21D2,ENO2,SRP72,CASK,PPME1,SLC29A1,SOCS2,RPS13,CTNND1,HSPE1,B4GALT7,HSD17B10,SNAP23,DLG1,TRAPPC1,ECD,EIF5A2,ISYNA1,CALR,MDM2,PRNP,ARF6,CD151,PPP1R18,CDCA3,EHBP1,TREML1,H2AZ1,SH3GLB2,SLC12A2,ELP3,GABARAPL2,ATG16L1,NF2,YKT6,GPX4,HMCES,RPA3,MME,EPHA2,AP2A1,DEPDC1B,RUNX1,VIRMA,FERMT2,YES1,NDN,ZNF622,MSN,GNPDA1,WDR45,CTNNA1,ENO1,CCNF,GAB1,MOB3C,HGS,PLS3,ISG15,SOX2,HEXA,FASLG,POLDIP3,XPNPEP1,VDAC1,KRAS,ICAM3,EFNB1,CDK5,MYO1B,CBL,AGR2,DDRGK1,CTNNB1,PPFIBP1,DYNC1I2,LYAR,SUMO2,TRAPPC10,CORO1C,DUSP6,SWAP70,FABP5,TNIK,PIH1D1,TRMT112,ACAA2,SDC2,MRPL12,NEK7,EFHD1,SYK,HSPA8,DDX39B,ICAM1,FTSJ3,BAG3,NCKAP1,ESR2,TAGLN2,VDAC2,NUPR1,NHERF1,ARPC3,TP53,SLC6A8,L1CAM,NUP107,AKAP12,PALM2AKAP2,SHC1,KARS1,SLAIN2,SLC38A2,FCHO2,SPPL3,CPNE1,AKR1B1,RPL32,CD274,PRKCA,FGFR1,WWP1,RPA2,CFTR,GTF3C4,PPP1R8,ZC3H15,LCP1,PML,BAP1,LIN7C,SEPTIN6,UBE2H,OAT,ATP1A1,PTTG1,ARHGAP21,RSPH1,ROCK1 |
| 7.456e-04 | -7.20 | positive regulation of endopeptidase activity | biological process | GO:0010950 | 156 | 65 | 18204 | 5365 |
CYFIP2,EGLN3,MIR15A,RPS3,DAPK1,BAK1,CLEC7A,MYC,BAX,BOK,ROCK2,MUL1,EPHA4,SMAD3,TNFSF10,TNF,VSIR,ACVR1C,APH1A,EFNA3,FASLG,AGER,PYCARD,KHDC1,S100A8,NKX3-1,HSPD1,AIFM1,BCL10,TNFSF15,NLRP1,PSENEN,FAM162A,SYK,MIR205,HMGB1,PDCD5,NLRP2,BAD,DAP,NCSTN,CRADD,PMAIP1,BCL2A1,PRELID1,JAK2,SEMG2,BCL2L1,ARL6IP5,RPS27L,HSPE1,MIR21,CTSD,PSME2,PPARG,FIS1,IFI16,PSME1,ANP32B,MCL1,FAS,NLRP3,IFT57,MIR17,HTRA2 |
| 7.459e-04 | -7.20 | ANAPC16 (anaphase promoting complex subunit 16) | protein interactions | 119504 | 63 | 30 | 19454 | 5460 |
MDC1,CMAS,H3C1,HAPSTR1,GRAP2,METTL15,ANAPC13,NEK2,ESR2,ZBTB2,DYRK1A,CCT7,CDC20,MAD2L1,ROCK1,MED17,FZR1,BUB3,ANAPC2,DOK4,BRD3,ANAPC4,CDC23,BRCA1,BTF3L4,ANAPC15,PYCR2,CDC26,PYCR1,CDC16 |
| 7.459e-04 | -7.20 | DCK (deoxycytidine kinase) | protein interactions | 1633 | 63 | 30 | 19454 | 5460 |
IRF2BPL,CSNK1A1,BIRC5,ADSS2,CSNK1A1L,CDK1,CBX3,DISC1,MAP2K3,CSNK1E,RANBP1,MSH6,RBBP7,HSPE1,PHB2,NUCKS1,HSPA8,IDH1,HSP90AA1,CHRAC1,RIOK2,MYC,CSK,ISX,KLK3,MBL2,TYMS,DCK,RXRG,EFHD2 |
| 7.459e-04 | -7.20 | PELI1 (pellino E3 ubiquitin protein ligase 1) | protein interactions | 57162 | 63 | 30 | 19454 | 5460 |
UBE2V1,H2AX,TANK,TP53,GOSR2,TBK1,VAC14,LMNA,SQSTM1,NBN,XRCC5,MYD88,BCL6,IRAK4,TICAM1,UBE2D3,PYCARD,TNFAIP3,RIMS4,TRAF6,RBBP8,PELI3,IKBKB,UBE2D1,UBE2I,UBE2N,SRPK2,PRKCQ,CNTROB,DAPK1 |
| 7.459e-04 | -7.20 | CKMT1B (creatine kinase, mitochondrial 1B) | protein interactions | 1159 | 63 | 30 | 19454 | 5460 |
PSMC3,EPHX1,TIMM29,CFTR,APOO,IMMP2L,HSPE1,SLC25A51,ARHGEF39,CLPB,HDAC5,HTRA2,LCORL,CBL,CA2,PPP1R16A,TPM3,HPCA,CUL3,PGAM1,CRIP1,PARL,SLC25A12,SFRP4,FBXO22,COPS7B,IGBP1,FUBP3,RXRG,CD274 |
| 7.464e-04 | -7.20 | GLI1 (GLI family zinc finger 1) | protein interactions | 2735 | 122 | 51 | 19454 | 5460 |
MYC,AKT1,TRIM32,CEP70,GCC1,CCT2,SMAD2,HSP90AA1,IGF2BP1,TUBA1B,TRIM27,PRMT5,RRAS2,BUB3,MAP3K3,ACTB,DYRK1A,GNB1,DES,WDR77,SUFU,PPP1CB,XBP1,CDK1,NUFIP2,IFRD1,ARPC2,SNX33,FXR2,PHB2,SAP18,PRPF19,RPL6,HDAC6,FEM1B,IKBKB,SMAD4,DDX1,TAF9,ALYREF,KRT8,SPPL3,NUP35,HSP90AB1,DHX15,TOP3B,CDK4,TP53,ZMYM3,CAPZA2,CRYBA4 |
| 7.464e-04 | -7.20 | SLMAP (sarcolemma associated protein) | protein interactions | 7871 | 122 | 51 | 19454 | 5460 |
PPP2R1A,DNAJC25,KBTBD4,PSMC3,VAC14,STIM1,SIKE1,PSMA5,CAMK2G,STK4,CSNK2A1,HDAC6,PRPF19,KXD1,PDCD10,PPP2CB,TNIK,PTPN1,STK3,CNTROB,GFOD1,DNAJC1,SEC62,FAXC,PTAR1,SSR1,RTN4,RAB9A,RAB5A,STK26,TACR1,SYVN1,IRF3,DVL2,ISCA2,FGFR1OP2,PFDN6,PFDN4,PFDN2,STK24,SEC61B,RMDN3,FAM83B,MOB4,PLP1,OPTN,CCSER2,APEX1,TAB1,DYNLL1,COPE |
| 7.473e-04 | -7.20 | CLN8 (CLN8 transmembrane ER and ERGIC protein) | protein interactions | 2055 | 32 | 18 | 19454 | 5460 |
SELENOK,GABARAPL2,TMEM107,PLP2,CD9,TMEM11,CYB5B,TMEM14A,STX8,PLP1,PDIA6,SPCS2,TMEM147,RTN4,ERG28,GPM6B,ARL6IP5,BNIP3L |
| 7.473e-04 | -7.20 | STXBP5 (syntaxin binding protein 5) | protein interactions | 134957 | 32 | 18 | 19454 | 5460 |
NAPA,STX12,STX1A,LAMTOR1,RHOG,BICD2,KXD1,SNAP29,STX7,STX11,STX6,VIRMA,NAPG,VTI1B,RUVBL1,SNAP23,S100A6,STX8 |
| 7.473e-04 | -7.20 | SAYSD1 (SAYSVFN motif domain containing 1) | protein interactions | 55776 | 32 | 18 | 19454 | 5460 |
SPPL3,UFL1,UFM1,TMED1,HSDL1,ODR4,SEC61B,HSPA8,RETREG3,SIGMAR1,REEP6,NAPA,RPS2,GPR17,BCS1L,CCDC85B,RPL26,TOMM40 |
| 7.473e-04 | -7.20 | C1orf21 (chromosome 1 open reading frame 21) | protein interactions | 81563 | 32 | 18 | 19454 | 5460 |
PPP2R5E,TMEM185A,GJA1,HRAS,RIGI,KRAS,CERS2,PPP2R1A,CENPM,PPP2R5A,MTRF1,CSK,DPP4,MOV10,DRAM1,RHOB,TRIM68,RHOG |
| 7.473e-04 | -7.20 | SYPL1 (synaptophysin like 1) | protein interactions | 6856 | 32 | 18 | 19454 | 5460 |
PPIF,TOMM22,ATG9A,PTAR1,CSK,RPA2,LMNA,SDCBP,SMAD4,VAMP2,ARFGAP3,RPA3,VAMP3,VAMP8,CIB3,VIRMA,HSCB,LGALS3 |
| 7.494e-04 | -7.20 | EMILIN3 (elastin microfibril interfacer 3) | protein interactions | 90187 | 55 | 27 | 19454 | 5460 |
NTAQ1,GORASP2,YPEL5,DICER1,ANKRD50,ARMC8,CCL4L1,FBLN5,LURAP1,SELENON,DDX39A,EMILIN3,CCL3,SDCBP,PNMA2,MKLN1,HAPSTR1,HECTD3,SQSTM1,RMND5B,GID4,TRIM10,GID8,MAEA,RANBP10,ERLEC1,CLEC12B |
| 7.494e-04 | -7.20 | KCTD2 (potassium channel tetramerization domain containing 2) | protein interactions | 23510 | 55 | 27 | 19454 | 5460 |
GNG12,KCND2,GJA1,FZR1,KCTD9,GNB1,CNRIP1,MYC,CUL3,GNG2,DDRGK1,TMEM255A,UBE2H,MIS12,HUWE1,UFL1,FBXW7,KCTD17,GNB4,FBP1,DLG3,TRIM6,GLRA2,TMEM45A,GNG7,NHERF1,UBE2M |
| 7.494e-04 | -7.20 | SLC30A4 (solute carrier family 30 member 4) | protein interactions | 7782 | 55 | 27 | 19454 | 5460 |
RAB11A,CIAO1,LAMP2,LAMP3,LAMTOR1,BTN2A2,TMEM100,NAPA,GNAO1,YES1,HNRNPL,NOP9,GOSR2,FUT8,RAB4A,TFRC,STX8,RAB5A,RAP2A,RAB9A,NSG1,TMEM60,KRAS,TNF,LEPROTL1,GNB4,STX7 |
| 7.496e-04 | -7.20 | ribosomal small subunit biogenesis | biological process | GO:0042274 | 103 | 46 | 18204 | 5365 |
RPSA,PNO1,RPS14,RPS17,NOP9,GTF2H5,UTP6,NOP58,EMG1,RRP7A,MRPS7,RCL1,RPS4X,NOL7,RPS7,UTP25,RPS15,IMP3,PWP2,RPS12,LSM6,RPS11,RPS23,FCF1,TSR2,NOB1,RPS9,SRFBP1,MPHOSPH10,WDR3,RPS5,SURF6,AATF,RIOK2,KRR1,TSR3,RPS13,NGDN,RPS16,UTP15,UTP23,RPS24,IMP4,RPS28,XRCC5,RPS27L |
| 7.500e-04 | -7.20 | SLC9A1 (solute carrier family 9 member A1) | protein interactions | 100009586 | 42 | 22 | 19454 | 5460 |
GAPDH,HNRNPA1,ACTN4,SFN,RPSA,CALR,CTSD,HSP90AA1,YWHAZ,HSP90B1,MSN,PGK1,ENO1,RPL9,HSPD1,VDAC2,CAPZA1,HSPA5,HSP90AB1,VDAC1,TXN,PRDX2 |
| 7.500e-04 | -7.20 | FBXO31 (F-box protein 31) | protein interactions | 79791 | 42 | 22 | 19454 | 5460 |
DNAJC19,PARD6A,GHR,SNAI2,ZCCHC9,CTNNB1,CCNQ,CFL1,COPS5,CCND1,MYC,AKT1,SKP1,PRPS1,VIRMA,CDC20,MDM2,FAM98A,FZR1,RNF113A,QSER1,MAP2K6 |
| 7.514e-04 | -7.19 | positive regulation of interleukin-8 production | biological process | GO:0032757 | 63 | 31 | 18204 | 5365 |
MAVS,TLR3,TIRAP,TLR1,CD2,CHI3L1,TLR7,TNF,ADIPOQ,RIGI,CLEC7A,HYAL2,RAB1A,IL6,MYD88,TLR2,BCL10,CD14,IL1B,AFAP1L2,HMGB1,SYK,TLR9,PYCARD,DDIT3,LEP,TLR4,TLR8,LILRA2,TLR5,CD58 |
| 7.527e-04 | -7.19 | regulation of leukocyte differentiation | biological process | GO:1902105 | 329 | 124 | 18204 | 5365 |
RAG1,CCR1,TOB2,IL15RA,RB1,BAD,TMEM176A,IRF7,HCLS1,FOS,IL2RA,IL5,IL2,CCR2,IRF4,TGFBR2,EEIG1,CCL19,RHOH,CTLA4,CARTPT,SOD1,TRIB1,XBP1,PRKCA,NDFIP1,NLRP3,TRAF6,MIR145,TESPA1,CTNNB1,TOX,IL2RG,VSIR,ADIPOQ,TNF,EP300,ACTB,NOTCH2,CD2,IL10,FCGR2B,TESC,FBXW7,DUSP10,BATF,AGER,PPP3CA,HMGB1,SYK,C1QC,KLF10,BCL6,CD28,TFE3,CBFB,CD80,IL23A,DROSHA,UBASH3B,IL7,IL15,IFNB1,FBXO7,TYROBP,LGALS3,SMARCB1,RC3H2,WNT10B,IL34,PRELID1,CD46,LILRB4,INHA,CTNNBIP1,IFNA2,MIR30B,CD4,MIR21,SOCS5,RUNX1,SMARCD3,PIK3R1,TLR9,IL4,IRF1,TCTA,ZBTB16,CREB1,SFRP1,MITF,MYC,TNFAIP6,BGLAP,CD86,MIR223,FOXP1,ACTL6B,IFNG,MMP14,IL12B,SOS2,TLR3,FGL2,BTN2A2,HAX1,TLR4,RNF41,KLHL25,GPR137,SMARCE1,CDK6,CD83,CCL3,PNP,PRDX2,IL18,ACTL6A,SASH3,NKAP,JUNB,LILRB1,FOXP3,TMEM176B |
| 7.534e-04 | -7.19 | SLC35B2 (solute carrier family 35 member B2) | protein interactions | 347734 | 85 | 38 | 19454 | 5460 |
RHOH,RHOJ,RAMP3,TMEM248,GNAI2,TMEM237,HSP90AB1,OPRL1,LMBR1L,ANXA4,CYB5R3,SYP,RHOG,AHSA1,HSP90AA1,TYROBP,SCN3B,SLC7A14,SLC7A1,SLC15A1,LPAR1,GPM6A,EDEM2,RHOU,BAP1,TSPAN15,HSPA8,BSCL2,LMNA,STOM,PDHA1,CRELD1,ACACA,TOMM22,TP53,RND2,CDC42,YIPF3 |
| 7.595e-04 | -7.18 | endometrium-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-endometrioid_carcinoma | 15680 | 4552 | 16828 | 4835 |
P2RY4,FBXW4,CD209,TAS2R7,ST3GAL2,PTGFR,IL2RB,IP6K1,SPINK9,SLC25A24,GK5,GLCE,STAR,RPL10,TRIP4,PDCL,SUPT5H,CYP4V2,APLNR,CNPY3,NCAPG2,SRI,PSMD3,DTWD2,GPR160,POLR1D,RNF10,FAM133B,OR51E2,GP9,KRTAP8-1,POLE3,TEX261,OR4D5,ZDHHC16,MDFI,RAP2A,MSH6,TNFSF15,SLC6A2,AIP,CD40,CRY1,NOG,ARFGEF1,MED22,TLR8,PMPCA,PYCR2,CDIPT,TNFSF8,ZNF428,PDE2A,CDK7,SIN3A,PSMD7,SCAND1,PLAC1,RAB6A,RGN,CTTNBP2,OR4A47,DCTPP1,TMEM100,CD34,FBXL4,UNC79,THAP1,CPXM1,EID2B,PRCP,TRAF3IP3,PIWIL1,CCDC90B,RGP1,TAB2,SRPK2,PRSS8,LDB2,YPEL4,GADD45G,RNASE9,RPA2,TMEM107,SAP18,EXOC3,TMEM81,CAP2,SLC22A6,TIA1,SPG21,DDR1,HSPD1,EIF1AX,PIAS1,PNPLA4,NPC2,TMEM115,PARD6A,TCEA2,LRRC28,TMEM183A,DPEP3,BTG3,OR1M1,CD9,RUSC2,GRPR,IGFBP3,TGFB2,RBMS2,SLC25A27,VPS54,S100A11,ATG9A,ZNF622,THOC3,GLOD4,PIGA,MX1,BOLL,TRIM44,NR1I3,PAIP2B,LRP10,CCDC3,VAV2,ITGB8,TMEM229B,NUFIP2,CMC1,HINFP,GNB3,CRYBA1,MPV17L2,WDR45,THAP8,NRM,HSPA5,SERTAD2,GNA11,FAM20B,TICAM2,FHL3,PPWD1,GPRASP2,PQBP1,OR8B4,TMEM165,KLHL25,SULT1B1,RPE,VEZT,SLU7,MFAP3L,FAM3C,PTP4A2,IRF7,SLC25A5,OAZ1,LYZ,WSB1,CYBRD1,ZNF518B,ADCK1,FAM151B,SLC35E4,MRPS17,SGIP1,MECR,MRPL9,FEM1B,UPRT,SUPT3H,FXN,TOX4,KLRC2,RAMP3,CPNE2,TMBIM1,IFT172,CYTH4,TRIM26,NUCKS1,IER3,CENPL,SNRPE,RRAGB,GRIK1,DLGAP4,CMA1,ANXA4,RASL12,IL18BP,GALNT2,GORASP2,THUMPD1,GMPS,PELO,TTC9C,IGF1,CCR7,SNAP25,RXRG,CDC23,MBD3,ELFN1,DMPK,TANK,SYNGR3,BRAP,MPG,RDH11,PIH1D1,KCTD3,ELFN2,RP9,GALC,HAUS2,OR5M9,SSPN,GNGT2,CNPY1,LRRC8A,LBX1,NKAP,SRFBP1,PFKFB2,ARHGAP12,EIF5B,ACER3,MREG,DIRAS2,YTHDF2,ANKRD6,PDE12,FAM161A,LMO2,FKBP1B,LCORL,EDA2R,OR13A1,MAGEC2,PSEN1,CLEC6A,KCTD17,RASSF8,SSBP4,AQP11,TLCD1,RBP2,ZNF581,SUCLG2,PDE7A,DUSP3,KIF3C,CIAO1,ATP8A1,GHRL,VPS18,NAA16,GJC1,SLC12A2,RUNX1,SCML1,ZFAND6,TYMS,TAPT1,SPRY1,RPS10,CLDND1,ETNK2,CCDC106,TRAF6,TBCCD1,KRIT1,VPS72,KCND3,FUBP3,ROCK2,TKTL1,GIN1,RPL18,MGMT,TRAPPC6A,MDC1,MTCH2,ITM2B,CCSER2,IMPA2,TRAM1,TADA3,TMEM196,UBA52,AP1M1,FUNDC1,ECHDC1,TPPP3,ZNF263,CA2,SNX10,PET117,MTDH,USP6NL,SGTA,TMED9,GSTCD,DLST,GTF2F1,SSX2IP,BCL6,SYNPR,TRPC1,ELMO2,LYPD6,ASPA,CBX3,DR1,GTPBP8,HS2ST1,MIS12,GABRA1,CAND1,PRNP,HSD17B10,TMEM89,PIK3AP1,XAF1,COX6C,PICALM,VTA1,RPIA,COCH,FEM1C,NUDT2,ATP1A3,GH1,PEBP4,BAX,PSD2,CRTC2,GSTM4,TMEM38B,TSPAN15,NPM3,PIK3CA,IVNS1ABP,FAM83B,SNRNP40,JAKMIP2,PSMC3,CDH11,TMEM185A,NDUFS2,AP1S2,LY96,TMEM47,MAD2L1BP,AKR1B1,SF3B1,TAB1,ADORA3,APEX2,ZBTB39,RBM27,CPT1B,CNN3,ANKMY2,RPL26L1,PHF13,CGGBP1,FOXA3,KLHL1,CARTPT,SESTD1,BANF1,ABHD12,NF2,PARP2,GGH,PPAT,IL17F,CYGB,NUDT9,TFB1M,SUMO2,SNRPB2,LZTFL1,KLF3,CCR4,CD81,CRISP1,LRRC40,ELK3,DPH3,UBE2E2,FSTL1,POLDIP3,HGS,RHOBTB3,DBR1,TAS2R13,TMEM170A,RNF133,COX6B2,TSPAN17,PRKRA,WDSUB1,GNRH1,PRKCE,ZNF451,CDC20,WDR5B,ZDHHC4,ACCS,XRCC5,TIMP4,ADTRP,SNRPG,PEX13,AIPL1,FHOD3,SLC35B3,NHEJ1,WDR11,TYROBP,SEC13,IL2,NBN,VMAC,TNFAIP8L1,PRL,MPPED2,CDC7,SLC19A3,OLR1,NDST3,FBXO8,MGAT4A,RBBP8,SGMS1,MRPS34,CYP2C9,IGSF11,DUSP21,TRIM45,ATAD1,B4GALT4,CAV1,LXN,TCEAL8,YIPF3,RPS2,RGL2,ITGB5,TRIM34,TMEM205,NDUFC2,ICOS,AKR1C1,MRPS11,CSNK1G3,RAB39B,PRND,CPLX2,ABHD10,HUWE1,FTSJ1,CNTROB,SREK1IP1,TTPAL,UBE2L3,CCIN,MEPCE,EIF3G,CYP3A43,SPEM1,PDE4B,PAQR3,CREBZF,TRIM36,MRPS18C,NT5DC1,PROK1,JAK2,CBLN1,STK3,COMMD9,HSPB2,LY6H,LILRA2,TNKS2,PTP4A3,PLSCR1,DCAF12L2,ZBED1,CTXN3,CORO6,OIP5,TRIM29,RB1,PNMA3,DPH5,FAM53C,MCL1,HCAR1,TMEM127,GSTA2,HFE,DDAH1,GPR35,NDUFA1,ALG11,DMTF1,PLG,DLK2,CDK12,PSMB7,FBXW7,TNFAIP6,EPHA4,KCNJ2,GXYLT2,LIAS,CITED1,TXNDC17,ARL4D,CPLX3,TNNI3K,GCLC,PSMD10,NPY1R,PLCB1,GPC1,GPR17,PRSS23,ZNHIT6,ARL2BP,ING2,FAM149B1,FRZB,SPP1,TSR2,CHRM3,MAGED2,GJA1,SURF2,SLC29A1,AASDHPPT,TM4SF20,CCNA2,CAPN2,LSM14A,SLC8A1,OR8H3,ABHD8,ICAM2,STARD3NL,YWHAZ,OST4,TM4SF18,OR6X1,TNR,BOK,CEND1,EHD4,ZNF511,FAM81A,SLC25A1,HNRNPF,STAMBP,HOMER3,CXCR3,MAGEB10,PCGF6,GRM1,OR4K2,SLCO3A1,ADORA1,SPATA2,KCNJ10,SHPRH,TAF1D,SMUG1,SVIP,ASCC1,CDH7,SLC37A4,ZNF770,TPD52L1,DUSP18,RPS28,UBXN2B,MAEA,FBLN5,LYRM2,FOXD3,EID2,ZNF345,KIAA1958,CXCL10,COX7B,CDC42SE1,BGLAP,SDHC,RGS1,ASB11,FAM83A,RHOG,NOL12,TTR,SEC61A1,GAD2,RSBN1L,METTL18,MRPS26,PHF7,HMGB1,TUBA1B,THAP6,ARF1,EIF2B2,ZMYM6,BTBD10,ZBTB26,LRRC14,EMILIN1,PRDX3,PDCD5,PPIL3,PHTF2,ZCCHC7,DPAGT1,CTSA,LPCAT3,GPR83,SERTAD1,KCNIP2,ZHX1,HNMT,FA2H,ERRFI1,ASPM,EFNA5,ZC3H14,CETN2,TADA1,ZC4H2,PITHD1,LEP,SH3BP4,RIT2,CACNG3,IFNA13,OR4B1,OR5K1,PDZK1IP1,PDE6D,TNIK,S100B,LRFN3,UBE3A,FGR,MRPL12,RCHY1,SPHK2,FAM20C,ZDHHC24,ARF6,B3GALT2,PPT1,DOK5,MAP2K3,SEC22A,DCTN4,RPL7A,CXXC1,LSM12,FIG4,SLC41A1,PNRC1,TMEM106B,UCP2,UBE2I,MED29,MXD1,MFAP1,KRTAP4-1,MAP3K3,FHIT,ARL11,EZH1,ARGLU1,MRPL16,TECR,DICER1,MAGEB1,SLC6A7,IL21,RPL19,ZNF362,HBM,MSN,FGF16,POU5F1,SAP30,RNASE4,DDIT4L,SLITRK5,GLIPR2,TDP1,MID1IP1,SERINC1,SNRNP70,PLEKHF2,HINT1,TNPO2,THOC6,PYCR1,CCL11,RAB9A,RXFP2,RPAP3,MARCKSL1,SLA2,SDR16C5,IFNAR1,SPATA4,CMTM7,SLC7A1,CA12,TBC1D16,FMOD,ADRB3,RAB11B,STX5,ARL6,CCND3,CSRP1,LEMD3,HSDL2,LYPLAL1,OPRL1,RNF139,NUP62,SMG5,ABCF1,DUS4L,PLP2,DYNLL1,SRP72,DDIT3,SLITRK1,HCFC1R1,CACNB2,RPL28,EDEM2,FIS1,ARFGAP1,PIGC,MVD,STK38L,CYP4F22,PREP,SHC3,CCL24,SNRPD1,ALCAM,PTPN5,UFSP1,SMAD9,TIMM17A,RELL1,RNF182,LIPA,SLC39A10,HM13,BCAS4,TCEA1,PGAP3,LCN15,MB21D2,OAZ3,VCPIP1,GCHFR,GJB1,PRELP,KRT8,PCYT1B,CSF2,CHCHD2,TPST1,ZNF200,IZUMO2,AGGF1,LCP1,HNRNPH3,HDAC11,SIGLEC5,ATG16L1,TP53TG5,DIRAS3,TTLL10,RPL4,SEC14L5,SUV39H1,RGL1,DYNLRB2,CKS1B,SPAG11B,HBP1,RWDD1,SLC25A3,COPE,RBM41,PRKCB,IRF2BPL,LSM5,DCTN3,HCFC2,PABPC5,SPDYE4,BMPR1B,OR4M1,HS3ST1,TULP3,MPP1,BARX2,PSMD1,MED27,SRM,RANBP10,ADH1B,BLVRA,CRYBA4,PITPNA,FOXC2,CRYZ,PCBP4,MLH3,APOBEC3B,FAM193B,ESD,GPR37,CDKN2D,ATP6V1D,VWF,CHMP1B,CDK17,PSMB10,ART5,TMEM39A,VPS39,SUPT4H1,MYLIP,SART3,IFI16,PTPRZ1,OR5AN1,CLP1,CLPX,ATG3,CFTR,INA,TCTA,PCP2,TMEM231,ADD2,SOD2,SCN2B,TEF,ANKRD10,VSTM4,AMELX,PDCD1LG2,GLO1,RAB1A,FBXO31,MAP1B,ZDHHC17,CNOT8,PELI1,PIGK,MLN,KLF12,WDR12,IAH1,SOX9,KCNG3,CHST10,AKT2,ITPRIPL2,JMJD8,GAB1,PSMC5,APEX1,PRSS1,LCN1,RFC4,TLR5,TICAM1,HS3ST3A1,GPM6A,COTL1,PNPO,OR2D3,ETFA,APMAP,PRELID1,PSMG4,AQP3,RIMKLB,ECD,CD59,STAP1,ACTR1B,HTR2A,SMARCB1,DEXI,ALG5,SUGP1,ABCC2,FMO1,STARD5,SRD5A3,CLRN2,DCAF16,GTF3C4,MMP20,REG1A,C1QL2,PLCXD3,TSPYL4,OR4K13,DNM2,DIS3L,CA14,OSBPL8,CEP57L1,ARHGAP19,TACR1,NACC2,CHRM5,EMILIN3,MTA3,DRD3,NAP1L3,CEACAM5,TIMM13,XBP1,RPF2,GPR34,TBC1D1,PDLIM4,THG1L,ERCC3,GABBR1,MRGPRX1,LIPT2,HPCAL1,NAP1L5,SEMA7A,OR9I1,TRMT5,BCKDK,MED4,ZCRB1,CYB5B,NPBWR1,RPSA,PIK3CG,RHOH,ARHGAP15,ERLIN2,HYAL2,CCDC126,RRP7A,RBM3,CORO1C,RACGAP1,MAGEA4,STT3A,ZNF343,ZNF436,WBP11,DIO2,STARD7,CHTOP,SYPL1,GPR75,SETD3,TMEM126A,ACTL6A,FOSL2,GNPAT,ACP2,GFM1,HOXB8,SSH3,CENPM,SEC61G,EMX2,SLC7A11,RETSAT,POPDC3,FZD6,MET,GAL3ST4,ADIPOR1,TIMMDC1,UBE2V1,SERPINB9,SNX11,RPLP1,PDE6A,HELT,IMP4,B3GALT4,DLG3,RHOU,TMEM176B,RPL22,CEBPE,ATF3,RBM5,CTLA4,RANBP1,ACSS2,IFRD1,PDLIM3,PRSS37,MAP1LC3B,LDB1,CSRNP3,TRAPPC3,GMDS,WNT2,BIRC5,MFSD3,VPS26B,YKT6,ANKH,F2,ESYT1,ARL5B,CAMKV,HAPLN2,EDC3,AANAT,PRSS35,FKBP2,UNC45A,TBCEL,CYP26A1,GMNN,ISG20,RALB,NUDT1,TMEM87A,DTL,PSMG2,CTDSPL2,ARL6IP5,CEP70,ABHD2,SNRPA1,SNN,CCDC22,KDM1A,NDFIP1,OLA1,PRPS1,HAS3,BAD,TSPAN3,MGST3,UQCRC1,NOC4L,CRHR1,AKR1E2,GDAP1L1,PDCD10,SSBP2,WTAP,NETO1,PTGER2,CDR2,C9orf72,NAA30,HERC3,PSMB4,SEMA3C,DOK6,IRF9,HSD17B8,LSM4,CGRRF1,DDX39B,TRAF1,RSL24D1,SKAP2,CLK1,RASSF4,KCTD20,SERPINA3,ZMAT3,BRS3,KCTD16,SLC15A1,ZBTB6,PLEKHF1,AHSA1,TEX19,TRIM62,ZNF655,HNRNPAB,GPR78,USE1,ST8SIA4,TMEM168,CD200,SIAH1,LRP3,STRADB,NCK1,PHOSPHO2,SCG5,OR6C4,TMEM198,TRAPPC2L,RFX5,MAT2A,NMRAL1,COX7B2,CMBL,CDKN1B,TAF9,MEA1,HMGN4,SCHIP1,CDK8,BSCL2,RNASEK,COX10,PHF23,ELOVL3,CYB5A,MAEL,MTX2,VLDLR,DHRS7,CRB3,CLVS2,VAMP3,HTRA1,KIF3B,HELLS,LCA5L,MITF,RPL13A,FAHD1,TRIM8,WDR20,SYT4,HRAS,RPP14,TAGLN2,CLEC9A,IKZF2,RPL8,PGM1,HADH,NAT9,TFIP11,GABRG2,WASF3,PRKCQ,MEF2B,MRFAP1,SMCHD1,B4GALT7,VSTM2A,ZSCAN5A,CNOT6L,CLCA1,TMEM88,TRMT11,GTF2IRD1,CD1E,MRPL40,MAP3K12,ZDHHC15,RSPH1,FBP2,PPIA,TMOD3,SOX3,COX19,LRTOMT,DEFB121,CTSB,NCKIPSD,SKA3,ALKBH2,RPS29,LECT2,ACOT8,TRIM52,HNRNPA1,POGK,SLC16A4,NFE2,CDC16,GLTP,GNB1,INPP5E,ASB8,ORMDL1,GHR,MED30,SOCS4,MED9,TREML1,PYCARD,CUL2,SLC6A8,OR7E24,FOXP3,LDLR,VPS4B,GSTA4,RHBDD3,PPP5C,RBM42,PCMTD1,RASGEF1C,MAP2K6,CA10,MAD2L1,LACRT,SEPHS1,LILRB1,EMP2,OVGP1,DNAJC1,HCLS1,GPX2,TRIM46,GLRB,EHHADH,PAQR9,IL4,TIAM1,THAP2,STBD1,FAM110B,LSM14B,TUBB,ZFP64,COIL,SYCE3,FAM50B,SFTPA1,STX10,RING1,ZNF596,SFN,MCHR1,TRAPPC10,GNAI3,PSPC1,SF3A1,CHID1,DISC1,NETO2,SMARCD3,AVPI1,SSR1,RBFOX3,HP1BP3,OSGEPL1,TLCD2,TAS2R16,PACRG,EIF4E2,GRM8,UTP15,MCM8,DLAT,RMI1,RIMS3,MT1A,CD38,ANKRD49,PNMA2,PHC1,TAAR6,UGT2A3,PLXNC1,SELENOT,EPYC,DCP2,MED17,TMEM184C,NOB1,GEMIN7,ZBTB33,PHF12,BAG2,ZNF7,RNF41,XPNPEP1,PLP1,DCAKD,MGAT4B,CYP3A5,DCUN1D3,LMNA,PHF1,IRAK1BP1,TIMM8B,TMEM74,CDC42EP4,EIF3E,CTBP1,MSRB3,ALKBH3,EXT1,JUP,KLRD1,FASLG,SNX5,CFL2,SLMAP,ZMYM2,OR4N5,BUB3,NR4A2,NOSIP,SLC25A45,UBAC2,SFXN1,CD4,NME2,KCNF1,UBXN6,CACUL1,ACO1,GANC,PCK2,PPTC7,RALGAPA2,TAS2R46,OR5I1,PRMT5,BEND6,TRA2A,SATB1,DRP2,DYRK1A,STC1,OR8K1,RAB31,KLHL32,SRGN,SLC25A20,TSHR,INSM2,AIG1,NEUROD6,EIF2D,EIF2AK2,LGI3,C1GALT1C1,GTPBP2,COPS2,TRIM27,SSBP3,NXPH3,DEFB115,SNX2,NOL7,WFDC5,CAMK1,NSA2,TACO1,IRF2,TM4SF1,BCCIP,PTTG1,ERP29,NOVA1,INPP5K,SEC63,NUDCD3,MCAT,CDC40,SCN1B,OR52W1,SUB1,TM2D2,NDUFB5,NELL2,PCSK2,ARHGEF6,DCAF4,CPE,CYP4F12,SLC39A13,LRTM2,CYB5R1,MYT1L,USP2,REXO2,DTD1,GPHA2,NTF4,POC1B,RPL17,SERPINB11,UBL4A,GKAP1,HECTD3,PI15,FGL2,FABP12,HDAC5,CLIP3,VAC14,SLC25A42,CBLN3,CRYGA,RNF208,GRIA1,YES1,GAPDH,NEO1,HSD17B3,PCCB,ESAM,NXT1,SLC35C1,ANKRD50,RLN3,CHMP1A,JRKL,RFC5,PATE4,IDH3A,NSDHL,MED13L,TMEM97,MADCAM1,POU3F4,MFSD6,ASRGL1,PSMC4,MPST,CCAR1,TSSK1B,NTRK3,PICK1,BOLA1,GGCX,PAQR4,ELOF1,RNF146,FAM76B,SNAP23,PDIA2,CLDN6,CAPZA1,STAC3,FAM3A,OR4N2,CDK5RAP3,FMO3,TNFSF10,NEK9,IRF2BP1,CSE1L,UBE2B,ACHE,GUK1,STX1A,AGAP2,FBXO3,PRPF18,IGSF21,MAPRE2,FGF7,EPHA2,CAV3,UCK2,LMBRD1,SRSF1,COX6B1,SLC31A1,DIO3,ITGA2,DCLRE1C,OR2J3,OR10G3,G3BP2,ZNF574,EXOSC8,KLHDC8A,POLD2,KDM2A,TSPAN7,IFT52,F7,FADS2,ACOX1,PIK3R1,NCALD,ANGPT1,KCNK17,ZGLP1,COPS4,KLHL23,HSDL1,IL12B,ACOT6,WDR6,DEFB124,INSIG2,LHB,CBL,ATP6V1G2,RAB6B,MMP14,MRPS35,MRAS,RALYL,MRPL41,DDI1,RAB28,COX17,FAM168B,ELK1,MDH1,CYP1B1,CD80,HNRNPL,IREB2,UBTD2,TAF11,NMRK1,CNOT7,ADRM1,RABIF,CH25H,OR2F1,HPS6,KCNH8,TCP1,CRMP1,CDC5L,LGI1,SLC35A5,TMEM19,ARMC6,SIKE1,NDN,CLRN1,DBH,TBC1D5,SNX3,IGF2BP1,GOSR1,NCOA5,MMAA,PPIC,LPAR6,GNAQ,POLR2C,NFE2L2,NGRN,RAD1,GIPC3,DBNDD1,CCDC167,SMAD2,USP46,PITPNB,ADRB2,TLR4,GPN2,SLC6A1,SRSF12,GPT,MYO1B,SLC2A1,QSER1,PAK1IP1,COL3A1,CBX7,VAMP1,GLYATL3,ADRA1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,UBTD1,TMPO,MAD2L2,COX6A2,POLR3GL,RBBP4,FAS,ABCB9,SKA1,CSNK1E,GRB10,PIGY,PAK6,ELOVL4,CHMP2B,RBP5,DNAJC4,EIF3D,ERVFRD-1,POLD4,MAN1A2,AKT3,CCDC92,LRRC4B,GREM1,TOMM40,MPHOSPH6,COX4I1,FABP4,ANAPC4,ARPP19,GDPD3,HDAC3,RPL29,GLRA2,MAP1S,BHLHE40,PI16,CARHSP1,NPC1L1,TIMM8A,KLHL9,C2CD2L,DNAJB4,TXNRD2,RAD21,RAP1B,AKAP17A,COQ10B,AIFM1,SNX14,LAT2,FITM1,ACTR1A,ACVR1B,FAH,RPL10A,CTDSP2,SDC2,LAMP3,CHPF,MATR3,CNOT6,S1PR4,TNFAIP1,FAM169A,TMEM11,KCNAB1,CRADD,PPP1R3C,AGTRAP,SEMA5A,APBB3,MCMBP,OR4S2,TLR10,CD28,ZBTB25,FXYD6,NAB2,SYNGR2,RNF11,CYTH2,APOC4,TAF7,PPY,CRYAB,ROMO1,GNL1,KIAA1143,SELL,ZNF473,ATP1B3,GNB1L,DNAJC2,ZC3H11A,METAP1,HTR1A,TMX2,WSCD1,ELF1,SFRP1,FGF23,SLCO1B3,GOSR2,CYP2R1,PRR5L,CD14,SLC25A39,G6PC3,RANBP6,ZNF704,PTPMT1,KBTBD6,EXD2,FARSA,UBE2H,PNMA5,MANBAL,CD86,SLC2A8,OXCT1,ENO2,CFL1,KLHL3,IRGQ,BRIX1,DPM2,RNASE6,TP53I3,RPS26,RNF40,DDX1,DAP,KDELR2,OR5V1,GPR173,PSMG3,TOP2B,TIRAP,RPS9,MYL6,GEMIN8,SEC23A,SLC6A3,CASC3,CNKSR3,TCF21,CALML5,PNMA1,VAPB,SP2,HEBP2,LILRB4,MYC,TAS2R39,TMEM50A,SMG8,CD40LG,FEM1A,EEF1E1,CMTM6,VPS26A,MKLN1,CCL28,MAB21L1,KCTD10,RAB35,SHISA2,PPP1R8,ASF1A,TNFAIP8L3,CDC42,SLC48A1,SLC38A1,DUSP10,BACE1,CLN8,VPS16,ACO2,SYK,SLC25A26,FTH1,SNX1,SLC35F1,PSEN2,CCM2,ALB,PIWIL3,IL2RG,PSMA6,PCSK9,KBTBD3,CLEC1A,AKAP1,DNAJC24,PARM1,CPSF4,LCN8,CD63,AGA,CACNB3,AGR2,PCBD1,TTC23,NLGN1,TMEM174,MORF4L1,LYAR,TOM1L2,UST,PFDN5,EXOC8,RND3,CNP,NUDT3,B9D1,TMEM156,GSTO1,AK2,SOCS5,GALNT1,CCDC69,PSMA3,MRPL13,MDM2,MGP,EHBP1,WDR38,SNX20,FIBIN,L1CAM,TLR9,FNDC8,FGD2,APEH,AKT1,DLX1,PRRC2A,DPP10,RPS23,CRABP2,IL20RB,DKK3,SF3B4,ASMT,CCNI,RAB11A,PPIL4,CDO1,SLC17A5,SLC25A31,ZNF671,UGCG,MEAF6,LYPLA1,LIG3,ATP6V0B,ZNF207,POLR3H,TMUB1,TRIM3,C1QC,E2F6,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,MRPL23,GDI2,GFM2,KLHDC8B,RNF141,DOK4,ARHGAP1,KLK9,PLA2G5,PDIA6,UBR7,SDR42E1,PRIM2,SNRNP27,CD99L2,TRIM32,LTBR,GAL3ST1,OR4D11,CASK,FGFR1OP2,GABARAP,PRPSAP1,GRPEL1,ELMO1,TCP11L2,UBE2D3,CCT2,CHRM4,ARMCX1,UBE2A,P2RY1,STRBP,ING1,OR8B8,IRF1,NAIF1,TRIM23,NHP2,ZMYND19,SLAMF9,TAAR1,CCR6,SEC14L1,ZNF319,ZNF397,APOBEC3A,XAGE5,GLUL,CNIH4,NRP1,NCKAP1,CDK5R1,CLU,ATPAF2,KIAA0232,LMO4,MYL12A,CYP39A1,HSD11B1,LRRC69,SWAP70,FAM8A1,EIF4H,ITK,CHDH,GNRH2,SENP5,IDH3B,GALNT4,GRM2,CTNNBL1,CYP11B1,TLR3,JAKMIP1,ADGB,GPAA1,SLC38A9,IL15RA,OSM,RMND1,PPP1R2,FAM78A,MIOS,ENY2,RAG1,MEF2A,IMMP2L,SLC35A1,DHRS4,HSBP1,MRPL24,MRPL50,ZNF304,SNAPIN,KLK3,SLC30A5,FBXO42,TMEM215,ZNF24,SERPINB10,TSEN54,MEST,FZD4,MTPN,WDR77,ATP6V1G1,LYG2,MFSD6L,ZCCHC10,SYN3,MX2,TMEM213,GPBP1L1,AAMP,DNAL1,NDST1,DEFB116,TNFAIP8L2,DHRS3,CDCA3,RAB3B,SMAP2,KTI12,AZGP1,INO80C,ABCB1,HBE1,PSME2,AZIN1,MAGOH,TBC1D10C,GTF2E2,LBH,JAK1,P4HA2,JOSD1,SUPT7L,KIT,RS1,LSM3,AFTPH,OR4D9,RARRES2,GRSF1,CSNK2A1,PIWIL4,KPNA1,GSTO2,KBTBD2,GNG7,ATF4,MYH2,SNAP91,HEBP1,ALKBH4,SLC7A9,PACSIN3,PGK1,VRK1,ROPN1B,TMIGD1,DNAJC5,DYNC1I2,CYP27A1,CDC73,UBAP1,ZYX,LHX2,MMP9,BTF3,FGFR1,PYGM,OR4K1,SHC1,PEX3,RCVRN,CCDC127,CD200R1,CRYGB,PPP3CA,KCNJ11,PRMT2,CIB3,TACR3,BUD31,SRP54,TMX4,CAMK2G,CCDC47,SCFD1,TTC4,GHITM,RPL15,TUBG1,CACNB4,ZNF593,ARMCX5,PRPF4,IMPACT,AGER,CD58,FKBP14,IDH2,RAB18,ENPP4,CCT5,PSMB5,MCOLN1,SBK2,SORD,SLC39A7,ANAPC2,FBXO32,AGK,SMCP,SIX5,TRIM21,ACTA2,ARMCX2,SPR,ARFIP1,GALNT12,PPARG,NFIL3,TRIM37,HECW1,ZBTB38,PTPN1,SETD5,HNRNPC,RMND5B,SLC25A21,RBBP7,PGS1,FAM199X,CLDN11,NIPA2,PAEP,RABL2B,TRAPPC1,SPTAN1,SLC35E3,RNASET2,LRP12,NPY2R,PKNOX1,ADRB1,ZDHHC14,RFX4,FRMD8,HEY2,RBM17,PCDHB8,RANGRF,NUDT19,THOC1,ABCC5,ATP2C1,FATE1,RC3H2,NUBP2,LDHA,UBXN10,SLC20A2,PCDHA5,GSK3A,PRCC,APOBEC3C,GPR162,RNF187,ZMYND11,SLC7A4,ZNF513,THRAP3,EEF2,SLC25A32,EFHC1,GJA10,EXOC2,XPO1,XPO5,INTS10,SURF4,TF,RNF103,CREB3,UTS2R,NEK7,SPOCK1,LASP1,PHKG1,MOB3C,FUT8,WBP2,GTF2A1,EIF2B5,SH3GLB2,GALE,CXXC5,OSR2,ENDOD1,ANKIB1,CIRBP,ZSCAN1,OR51S1,EIF4EBP3,WDR37,IL23A,PSMD6,FURIN,DHX9,SLC39A9,AQP4,CREBL2,TXNIP,CCL25,GNMT,GLE1,MSX2,PELI3,CDC37L1,SNAI3,KRR1,NLE1,NAA11,NDUFB8,ISYNA1,CXCL1,XPOT,FRA10AC1,PDIA3,WNT7A,STX17,LEPR,HADHA,LEAP2,DHX16,TRA2B,SOX21,RAB4A,OR6M1,NUDT16,GXYLT1,KCNA2,B4GALT6,LHFPL1,HSPE1,CLDN14,ZKSCAN1,STAMBPL1,SIPA1L1,PGBD2,SERPINH1,RPL37A,OXNAD1,RBM23,TMED1,HEXA,ADAT1,OCEL1,BRI3,CDKL2,KIF1C,CHRNA7,GAS8,CD3G,PAOX,BRMS1,NQO1,IPP,SPATA2L,TBCE,TAC1,OPA3,NPVF,AKR1C2,IGFBP4,LMBR1L,ST13,RASGRP2,LPXN,IL34,UCKL1,RAP1A,ACAA2,WWP2,RABAC1,FBXO30,TIGD7,POLR2I,CD2,TRMT6,PTCRA,NEDD8,CXCR1,FGF17,HBB,KCND2,CCL21,NDUFA5,SIRT7,FYTTD1,NOL4,IQSEC1,TAPBPL,RRAGA,ETV6,ABHD16B,TNFAIP3,ZBTB42,TRAF7,MMACHC,DUOXA2,MTMR12,SOST,TCP11L1,ZNF805,SV2B,HPCA,OR2A2,EIF4EBP2,SIVA1,GFOD1,SNAPC1,SNTA1,NDUFAF2,GPR37L1,SPRED1,ALDH1L1,MAK16,TSSC4,POLL,NONO,SLPI,CERK,USP39,ZNF174,USP38,SYNGR1,LSM6,RTP4,FGF13,PRKX,PROX1,VPS4A,ENPEP,NAB1,SFTPD,OAZ2,CLEC12B,RAB8B,CTNNB1,CYP2D6,INTS12,SOCS2,ESR2,DCAF5,CDK6,CWF19L1,ADCY3,SNRPD2,FAM13B,ANP32B,CHST9,CPT2,DCAF8L2,NDNF,AP1G2,PWP2,MTAP,RAB3C,CACYBP,CTSK,URM1,CETN3,NFYA,FAM200A,S100A10,STX8,TOLLIP,BATF,TGFB1I1,DUSP1,MPHOSPH10,S100PBP,MRPL47,TMEM33,KLF10,FAF2,BMPR1A,RHCG,SPINK13,SCG2,ARHGAP21,LCN6,SETD4,OTUD6B,CCND1,OR2W1,RPGRIP1L,TMED3,ACOT13,COX7A1,FBXO9,NPTN,FCAR,CCDC42,CYC1,POU1F1,ID1,PTDSS1,SLC35A2,ARMC8,ENTPD4,DEGS1,CRYBA2,INPPL1,KIF2A,MIA2,BACH1,NOP58,SPATS2L,AKR1A1,NFE2L1,RBCK1,MRPS25,PGAP2,CTSD,FABP5,MRGPRX4,SCAMP2,NUP107,OR52M1,SPEF1,PRKD3,CYP4F8,SLC5A6,DEK,NLGN2,PPIB,BPGM,HSPA14,CXCR4,NPY5R,POLR3B,HAND2,PGR,LCN9,BRD9,KCNH1,KIAA1191,CCL17,OR2H2,GTF2F2,DLG4,BICD2,SERPINA5,NAPG,RNF122,KIAA0408,RAN,RBM12,SQSTM1,GLIPR1,TMEM177,FMO2,CLDN8,ADAMTS1,CXCL14,TUSC3,RPL6,BNIP3L,DDX42,SLC7A14,GMPPA,CYB561D2,PPP1R16A,MT2A,ATP1A2,UPF3B,RABL3,ZNF576,GCA,PPP1CB,TRAM2,CHST1,FCHO2,MPV17,EHD1,RFXANK,TRAM1L1,SESN2,PAPOLB,PLAGL1,KLHL15,CRYBB3,OR4F6,FOXS1,PTRH2,TAS2R5,ACTR2,ACP6,SYNJ2BP,TMEM164,TMCC2,SELENOS,ZNF609,SLCO1A2,KCNK10,SRP14,NUS1,TMEM106C,KRT7,PLEKHA8,WDR3,GJB2,MANSC1,OPHN1,SUMO3,CCR3,ZNF687,OGG1,SFT2D2,RAB23,CMAS,RHOJ,CBLN4,WWP1,TMEM50B,IFNG,JUN,S100A8,HIRA,CD47,TNRC6C,SPTBN1,EIF3J,FERMT2,TOMM40L,GNPNAT1,GIMAP2,UTP23,CHI3L1,RNASEL,TNFSF18,PPDPF,DNAJC8,RAB33A,CRYGD,RNF167,FAM107A,CLDN22,EGLN3,FOS,DYRK2,MRPS28,RIOK2,OAT,POMP,OS9,NFKB1,HNRNPK,PRKAG1,LHFPL2,ACAP2,MAFG,SCD5,TAPBP,HNRNPA2B1,RCBTB1,GGCT,ATP6V1C1,OR2A25,FANCG,STX6,PLA2G15,MAPK1IP1L,RFTN2,TPPP,CAPZA2,RB1CC1,SLC35E1,NAA60,CCL8,YPEL5,PPID,BEND5,SNRPA,CMPK1,RAB2A,CTNNA1,GPIHBP1,WDR44,TRAPPC6B,CCNF,CRBN,CD226,SACM1L,VPS33A,B4GALT3,PDYN,ZFP1,KCNIP3,INPP4A,EZH2,ARCN1,FGFBP2,RAB9B,AMT,FN3KRP,WIF1,DYRK1B,PHYHIP,STAT6,OR10G7,ISG15,ACADSB,SNX24,EIF4B,PTHLH,MRTO4,SLC25A4,SMAD3,PPP2R1A,ELMOD1,MLF2,PLEKHJ1,TIMP1,DERL2,TXNL1,TMEM59,IL6ST,LYNX1,RPL23A,RAB37,SLC6A11,FOLR1,CAV2,CSTF2T,FBXO25,IFI35,PSRC1,C1QL1,TIMM10,SELENOK,STK38,AP1AR,PNP,RAB5C,PCDH19,WEE2,SLITRK2,ELSPBP1,STX18,ORAI3,FOXN2,RBFOX2,GK2,CDKN1A,OTUD7B,PPFIA3,SDHAF2,CLIC2,AKIP1,PIWIL2,SOS2,ROGDI,PGM2L1,GYS1,SLC23A2,FAM168A,ACTL6B,LY6G5C,SLC4A8,SNIP1,HRH3,ZBTB45,ABHD13,RPAP2,INHA,RGS5,OR5L1,RAB1B,NDE1,RBMX2,AMY2B,CCDC65,LDHAL6B,HMBS,TDRD7,CD2BP2,MRGPRX2,GRIA2,LRRC24,FLYWCH2,KLK5,LIX1,DDX4,TMEM91,SLC43A2,ZCCHC9,TOP3B,HIGD2A,B3GNT2,TEX12,TAF5L,MYEF2,PNPLA8,NGB,UQCR11,GLT8D1,MOV10,PCGF3,GPX5,TRIQK,TMEM14A,TCEAL7,GDE1,OR14J1,CPSF2,CDH8,MTHFD2L,CD36,IRF3,ERV3-1,PCMTD2,STOX2,KLC2,STXBP1,PAX9,PRKAB1,DPEP1,UQCRH,DERL1,IL18,SOX2,CSNK1A1L,ST3GAL1,SLC32A1,PARP11,ZNF501,CEP97,IFRD2,ST3GAL5,POR,STK24,LCA5,RAC2,LRP6,TAS2R40,MRPS21,PYROXD2,CDK4,NPR2,CNNM4,NR1I2,DPY30,BRCA1,PCDHB1,ABHD4,KCNK13,RBM7,TRAF2,ADPRH,PDHA1,MBD5,KCNMA1,NOS1AP,BCL10,RGS2,STMN2,NME1,DUSP19,TMED7,RNASEH1,DNAJC3,FKTN,KLK6,SERINC3,SLC41A3,STAU1,TSN,STOML3,EMP3,CHMP2A,OSTM1,CBR4,SLC19A2,VMP1,HSPA8,MSMP,GMPPB,CALHM2,TES,CCDC25,BECN1,LMNB1,EED,ABHD14B,ELP3,YAF2,CIB2,MRFAP1L1,ACSL4,DTYMK,TGFB3,TRIM24,ZNF592,MTRF1,EWSR1,GPX3,PROS1,TMEM204,SNAPC3,SNCG,BLOC1S2,SSU72,IGBP1,AKAP12,RAB40AL,DDX39A,TRIM5,EIF4E,CALHM3,LHFPL4,CDKN2C,COX4I2,SPECC1L,NAT2,RINT1,OR10G9,TSPAN5,BZW2,BCAP29,ZBTB17,FABP7,CD274,EIF3K,CREB3L4,B3GALNT1,PHYH,FUT9,RTKN,NTN4,ADIG,HOXD12,RPLP0,UBE2V2,IL10,EFNB1,RNF113A,SH3GLB1,PREPL,THTPA,OLFML3,TSPO2,GOLGA7B,PELP1,ITGA6,CSNK1A1,COMMD8,TFE3,DEFB114,MT1M,IFNA10,ISG20L2,HSP90AB1,POLE4,ZNF862,SYP,ATG4A,CSRNP1,FUNDC2,MRPS23,RER1,FCN2,CDKN2AIP,RGS7BP,SFRP4,DSTYK,ZC3H7A,CCR2,AIF1L,ZBTB5,TMEM123,CIDEB,ATAT1,TMSB10,IPO8,F9,NKX3-1,OPRK1,GCNT3,MYO6,CYP2C18,NDUFS8,ZNF740,GPR137,SNX17,BCS1L,APOO,TMEM144,TOP1,SRRM5,NRSN2,HTR5A,TMX3,EIF2B3,DNAJC22,CHGA,GBE1,PAPSS2,TCF23,GPR65,SEC61B,TEX30,TOM1,BCL7B,TRIM54,FAM98A,ACBD7,RPLP2,TGIF2,GREM2,POPDC2,GPX6,OR4Q3,HTR1F,CREBBP,PRPF19,GPAM,LDOC1,PDCD4,RDH10,SDF2L1,RUVBL1,GTF2B,CXCL3,NKIRAS1,OAS1,GIT2,CLDN4,SLC13A5,LAMB2,RAB3D,ZNF287,TMEM184B,KDM4B,ACAT1,TMEM114,EDEM1,GNG2,VAMP5,METTL14,MAP3K11,GTF2H2,MBL2,TOR2A,PTS,AMIGO1,JPH4,COL1A2,RMI2,SMU1,SLC35D1,R3HCC1,CSGALNACT1,SAT1,TFCP2,METTL2A,ABHD6,CLDN1,CCNB1,CTDSP1,FAM162A,NDUFAF4,CRYBB2,AKAP14,ALKBH5,ERH,ANKRA2,ADIPOQ,CRTAP,LCP2,UHMK1 |
| 7.630e-04 | -7.18 | DAP12 signaling | REACTOME pathways | R-HSA-2424491 | 356 | 140 | 10285 | 3229 |
FGF16,LAMTOR3,CAMK2G,IL2RB,VWF,IER3,PSMC1,CUL3,IL5,PPP2CB,LAMTOR2,KIT,HRAS,GAB1,PIP4K2C,PSMD1,PSMB2,PIK3CA,AKT3,PEA15,AKT1,PSMA6,SHC1,RASGRP3,PSMB4,SEM1,KLRC2,DUSP1,PSMC3,TP53,PSMA1,CD86,RPS27A,IL3,PSMD4,PHB1,SPRED1,IL2RG,PIK3R2,ICOS,YWHAB,MDM2,FGF1,PPP2R5A,DUSP6,PAQR3,MET,PTEN,PSMA5,FGF23,PPP2R5E,PIP5K1A,SPTAN1,PDE1A,PEBP1,PSMB3,FRS3,PSMD10,DUSP9,SRC,MOV10,PIK3AP1,FGF10,RAP1B,KRAS,MAP2K1,WDR83,FGF22,SYK,UBA52,RAF1,TNRC6C,CSF2,PRKCE,CDKN1A,PIK3R3,JAK1,FGF7,PSMD12,AKT2,SHC3,RAP1A,PSME2,FGF3,HBEGF,PSMD6,SPRED2,IL2RA,PSMB9,MAP3K11,BAD,GSK3A,GRAP2,DUSP10,NEFL,JAK2,PSMB7,CREB1,PSMD3,AHCYL1,PSMB1,PIK3R1,VAV2,ADCY3,PSMB5,PSMA3,PSMC4,CDKN1B,PSMA4,KLRD1,B2M,PSMB10,PSMB11,FGFR1,IL2,PSMC5,TYROBP,ADCY2,PSMA2,PSMB6,CSK,BRAP,DLG4,CD28,AGO1,PPP5C,SPTBN1,PDE1B,PSME1,ANGPT1,CD80,FGF17,PSMD7,PSMD14,PTPN11,PRKACB,PRKCA,PPP2R1A,UBB,LCP2 |
| 7.672e-04 | -7.17 | MCF2L2 (MCF.2 cell line derived transforming sequence-like 2) | protein interactions | 23101 | 37 | 20 | 19454 | 5460 |
SERPINH1,SNRPE,SF3B5,MRPS26,CHRAC1,CIRBP,RPS29,LBR,DPY30,STOML2,LDHB,MAX,MAT2A,SKP1,PSMD12,TXNDC12,CHCHD2,CDK6,TMEM263,SFXN1 |
| 7.678e-04 | -7.17 | RABGGTB (Rab geranylgeranyltransferase subunit beta) | protein interactions | 5876 | 102 | 44 | 19454 | 5460 |
NPSR1,RAB3A,RAB31,HRAS,RAB6B,GNB1L,SH3GLB1,MAP1LC3B,RRAGB,KRAS,B4GALT7,RAB1A,MAGED4B,RABGGTB,RAB27A,PPP1R16A,RAP2C,IRF6,RIT1,FAM219A,RAB11A,PRKACB,RHOBTB3,MCM3,LMBR1L,RRAS2,RAB9B,RPA2,PTP4A2,GIT2,PTAR1,RPS14,NOTCH2,RAB37,PIP5K1A,TAFA1,RAB6A,YKT6,MCMBP,RPA3,ARHGEF6,RAP2A,RAB5A,RAB9A |
| 7.721e-04 | -7.17 | CKMT1A (creatine kinase, mitochondrial 1A) | protein interactions | 548596 | 74 | 34 | 19454 | 5460 |
PHB2,VDAC1,HSPE1,HSCB,UFL1,SFXN1,SLC25A5,MAP1B,RPA3,EMC2,PMAIP1,RPA2,PSMC3,PIH1D1,EPHX1,CDK7,CFTR,SOX2,FBXO22,FZR1,ESR2,COX4I1,RXRG,AIFM1,SNRNP70,PPP1R16A,UBE2H,CBL,CUL3,PGAM1,CRIP1,TPM3,HNRNPA1,HPCA |
| 7.721e-04 | -7.17 | ERCC6L (ERCC excision repair 6 like, spindle assembly checkpoint helicase) | protein interactions | 54821 | 74 | 34 | 19454 | 5460 |
HSCB,ZDHHC17,RPA3,PML,CLPB,RPA2,CDK1,FEM1A,EIF4B,CAPN2,ACACA,ATG16L1,TIMM8A,CFTR,LMO4,LDHA,PRNP,EGLN3,CDC5L,VIRMA,LMBR1L,CCNF,EEF1AKMT3,FAS,SMAD4,FBXW11,RB1CC1,MLF1,UBXN6,SFN,XPO1,YWHAG,H2BC9,YWHAH |
| 7.721e-04 | -7.17 | TNFAIP1 (TNF alpha induced protein 1) | protein interactions | 7126 | 74 | 34 | 19454 | 5460 |
HEXIM2,CSNK2B,DCUN1D1,COPE,TRIM54,KCTD10,XPO1,NTAQ1,SUV39H1,BAG3,ZMYND19,CUL3,NRP1,EPHA2,LSM3,ARMC7,RHOB,PCNA,TNFAIP1,EMC2,DVL2,FAF1,PML,ZDHHC17,PSMA1,KDM1A,FXR2,PPP1CB,UBE2M,EIF4B,SMARCB1,STK16,PRKAG1,CAPZA2 |
| 7.721e-04 | -7.17 | COG7 (component of oligomeric golgi complex 7) | protein interactions | 91949 | 74 | 34 | 19454 | 5460 |
PHYHIP,RAB1A,RPA3,CD40,POC1B,BLOC1S2,RP2,NPTN,COMMD8,FAM234A,COMTD1,PTAR1,SNAPIN,CA14,RPA2,CYB5B,KRT7,CD274,SEC23A,ACTB,LYRM2,TAX1BP1,RAB1B,COG1,HSBP1,ILVBL,GPR17,OPRM1,EMILIN1,ENDOD1,MUL1,MAP4,CCHCR1,HNRNPD |
| 7.729e-04 | -7.17 | INCA1 (inhibitor of CDK, cyclin A1 interacting protein 1) | protein interactions | 388324 | 239 | 90 | 19454 | 5460 |
FRS3,FEM1A,GTF2H5,THAP6,TRAPPC6A,NMRK1,GSTO2,FGF16,CDKN1A,LMO3,NDUFAF3,SAP18,LYPLA2,GRXCR1,BOLA3,ACTMAP,ATPAF2,RAMAC,NUBP2,ARMC7,LMO2,CDKN2D,ZDHHC24,SNRPB,BAG3,LGALS3,MAD2L2,FAIM,DOK4,CPSF1,SCNM1,STK16,CKS1B,YIPF3,SPG21,UFM1,HNRNPF,CHCHD2,TRIM26,RNF26,TFG,RFC3,CTTNBP2,MAGED4B,CDC23,STAMBPL1,TEX12,PFDN5,RAB5C,HR,SMUG1,MPP1,HOMER3,GYS1,TSG101,TRIM68,ING5,VPS28,TXNDC17,RALB,PSMB2,ZMYND19,NTAQ1,CTNNBIP1,MAGOHB,KCTD9,UFSP1,CINP,UBASH3B,ILF2,KLHL26,SPRY1,MSRB1,ZNF32,CDK4,UBXN2B,EXOSC8,POP5,TRIM63,PHF1,SMG9,AKAP8L,LSM3,HENMT1,PLSCR3,VPS26C,MALSU1,UBTD2,EPHB6,METAP1 |
| 7.742e-04 | -7.16 | GLUTATHIONE_PEROXID_3 | prosite domains | PS51355 | 8 | 7 | 12186 | 3388 |
GPX7,GPX3,GPX5,GPX4,GPX2,GPX1,GPX6 |
| 7.742e-04 | -7.16 | GLUTATHIONE_PEROXID_2 | prosite domains | PS00763 | 8 | 7 | 12186 | 3388 |
GPX2,GPX1,GPX6,GPX7,GPX3,GPX4,GPX5 |
| 7.780e-04 | -7.16 | TRPM7 (transient receptor potential cation channel subfamily M member 7) | protein interactions | 54822 | 128 | 53 | 19454 | 5460 |
ARL15,SSR1,RND2,OTULINL,CDC42,SEC62,ST7,PXMP2,STX7,FBXW7,RAB9A,RHOU,RPL27,RIT1,RHOB,YWHAZ,RAB2A,SFN,SEC63,RHOJ,SEC61B,PLCB2,RND3,RPN1,EEF2,SNAP29,FKBP8,KRAS,PLCB1,CYP2C9,TMT1A,YWHAB,RHOG,ESYT1,LAMP3,YWHAH,YWHAG,LAMP2,RAB5C,NDC80,SLC25A46,DIRAS3,LMAN1,DNAJC1,ARF6,EIF2B5,RHOH,GJA1,HSD17B11,RAC2,PTPN1,HRAS,RAB35 |
| 7.780e-04 | -7.16 | SLC30A5 (solute carrier family 30 member 5) | protein interactions | 64924 | 128 | 53 | 19454 | 5460 |
ABCC2,NUCKS1,LPAR1,EP300,CYB5D2,CTBP1,OTULINL,SEC62,BET1,FUT8,TPRA1,FAM234A,ESR2,IL2RA,TMEM74,DPEP1,ARF1,CD79B,S1PR4,IGF2BP1,RIC3,GORASP2,CSGALNACT2,GPR17,RAB2A,CSK,SAR1B,TMED7,ARL5B,SLC39A7,CD83,RAB1A,CYB5B,CRELD1,TRAPPC13,VAMP2,IL1R2,POLE3,CX3CL1,RAB1B,TRAPPC10,RAC2,GJA1,RNF128,SRSF1,DNM2,HNRNPD,TRAPPC2L,LAMP3,CCR6,RAB5C,LAMP2,MDFI |
| 7.780e-04 | -7.16 | UBE2E3 (ubiquitin conjugating enzyme E2 E3) | protein interactions | 10477 | 128 | 53 | 19454 | 5460 |
RNF8,RNF181,RNF126,TOPORS,NFE2L2,ACVR1,ZNRF1,TRIM62,FBXO25,TRIM63,TRIM37,PCGF3,RNF115,UFM1,RING1,PICK1,RNF167,USP15,CBL,MUL1,MARCHF5,WWP2,RNF14,MDM2,HNRNPL,TRIM45,RDH12,DET1,RNF11,HMGB1,RNF5,ARRDC3,RMND5B,RNF10,HSPA8,WBP2,HERC4,DTL,BMERB1,RC3H2,BRCA1,UBE2E3,SPOP,CUL3,TRIM32,UBB,SIAH1,PGPEP1,TRIM54,TRIM27,RCBTB1,NFKBIA,STUB1 |
| 7.847e-04 | -7.15 | MAPRE1 (microtubule associated protein RP/EB family member 1) | protein interactions | 22919 | 504 | 174 | 19454 | 5460 |
LSM14A,PABPC1,EWSR1,ACTR1B,PSMA1,VDAC1,NUP42,PAX6,PPIL3,TRAF2,TUBA1A,KIF2A,NUP37,SEC61G,KLHL12,RAB35,DYNC1I2,SUMO3,HSP90AB1,BAZ1B,DDX50,XPO1,CTNNB1,CBL,DRG1,MAGOH,LCA5,PEBP1,JAKMIP1,SPECC1L,HSPA8,EP300,EEF1G,SSR3,STAU1,SAP18,MRPS7,NUP62,PAFAH1B1,ZC3H14,CD59,EIF4B,SNRNP40,PSMD6,COPS7A,LMO2,UFD1,BAG3,KIAA1191,MAP1B,ABCE1,NUP107,CAPZA1,ACTR1A,CAPZA2,DNAJC2,NUPR1,SSBP1,ADD1,RPS27L,DKC1,SLAIN2,CMSS1,COPS5,RPL10A,BAP1,ZC3H15,HSPA5,SPTBN1,SUMO1,CD2AP,CDC42,RPA2,UBE2M,PRKCA,TRIM36,CCSER2,CYBC1,EIF2S2,SRP54,MACROH2A1,EIF4H,SRPK2,SRC,ARHGAP21,PRKACB,BICD2,UBE2H,BAG2,COX8A,G3BP1,PSMD12,MCM6,JUN,ACTN4,NUP153,EZH2,STIM1,SKA3,SNRPE,GPR137,HP1BP3,RPLP1,KRT8,RPL7,SPTAN1,CEP19,NUP35,MAP1S,CDK5RAP3,CAMSAP2,NUP50,DCTN3,UCHL3,GPC1,NDE1,MTX2,PPP1CB,ABCB1,PSRC1,FAU,SNRPD2,SYBU,RPL35,TUBB,DYNLL1,TENT5C,PRRC2A,TMCC1,VEZT,SMARCE1,RPS29,FAS,YWHAZ,PPP1R12A,PQBP1,IFT52,CAMK2G,OLA1,ACTR2,CASK,PSMB1,CGAS,MAPRE2,H2AC14,HDAC6,TMEM184C,SSX2IP,RPA3,DCTN6,MAVS,ARPC2,SGF29,EIF5B,TPT1,EDF1,DCTN4,JUP,TMOD1,SHOC2,CCNF,CHRM5,CTNNA1,EIF4A3,CTTN,UBE2I,YES1,DYNLT3,GNAI2,CEP97,STK11,CASC3,MAPRE1,PPIG |
| 7.852e-04 | -7.15 | purine nucleoside triphosphate metabolic process | biological process | GO:0009144 | 182 | 74 | 18204 | 5365 |
NDUFA12,ATP5MK,COX11,NME2,NDUFB7,GTPBP1,NDUFA5,ATP5MC3,ENO2,PFKFB2,FKRP,NDUFS8,NDUFA1,LDHA,NME1,NDUFB10,ATP5F1A,NDUFAB1,HTR2A,ENO1,PGAM1,OLA1,HSPA8,NDUFB6,PGM1,IER3,NDUFV2,ATP5F1B,NUDT2,ATP5PD,RAB23,UQCC3,ATP5PB,STOML2,DNAJC30,UCP2,ADK,GNAI3,NDUFS2,ATP5MG,PGK1,ATP5PO,SDHB,LIPA,ATP1B1,AK5,NDUFB8,ATP1A2,BPGM,NDUFA2,RAN,NUDT5,SDHC,NDUFS6,MFN1,NDUFC2,OGDHL,ATP5PF,GUK1,NDUFB5,ATP5F1D,ATP5MC1,NME4,ATP5F1E,SAMHD1,AK3,BAD,NDUFS3,CLPX,ATP6V1A,NDUFB4,NUDT16,GAPDH,AK2 |
| 7.852e-04 | -7.15 | ribonucleoside triphosphate metabolic process | biological process | GO:0009199 | 182 | 74 | 18204 | 5365 |
ATP5MC1,ATP5F1D,NDUFB5,NME4,BAD,AK3,ATP5F1E,NDUFS3,CLPX,NDUFB4,ATP6V1A,UCK1,GAPDH,AK2,LIPA,SDHB,ATP5PO,PGK1,ATP1B1,AK5,NDUFA2,BPGM,NDUFB8,ATP1A2,RAN,SDHC,NUDT5,NDUFS6,ENTPD4,ATP5PF,OGDHL,NDUFC2,MFN1,PGM1,NDUFB6,IER3,ATP5F1B,NDUFV2,NUDT2,ATP5PD,RAB23,UCP2,STOML2,DNAJC30,ATP5PB,UQCC3,GNAI3,NDUFS2,UCKL1,ATP5MG,NME2,ATP5MK,COX11,NDUFA12,ATP5MC3,NDUFA5,NDUFB7,GTPBP1,ENO2,FKRP,PFKFB2,UCK2,LDHA,NDUFA1,NDUFS8,NDUFAB1,ATP5F1A,NDUFB10,NME1,HTR2A,ENO1,PGAM1,HSPA8,OLA1 |
| 7.852e-04 | -7.15 | ARRB1 (arrestin beta 1) | protein interactions | 408 | 301 | 110 | 19454 | 5460 |
ADRB2,XRCC5,EP300,ARRDC3,HSPA8,MYL6,EIF4B,WDR77,MYH1,RPL7L1,TUBB,ATP5F1B,GNB1,APEX1,NFKBIA,SNRPD1,EDNRA,PRMT5,H1-10,YWHAZ,ELMO2,HSP90AA1,CUL3,G3BP1,RPS27A,SCYL2,ZYX,JAK1,ADRB1,HGS,KLHL12,ZRANB2,NAA15,MAPK10,JUN,SPTAN1,HNRNPL,INA,RPL8,TRAF6,PPM1B,DCAF5,H2BC17,YWHAB,RPL6,DPY30,YWHAG,HNRNPA1,YWHAH,STK38,PIK3R2,HSPA5,PRPF4,DVL2,ACACA,MYL12B,UBA52,CDC42,YES1,TMOD3,RPL22,SRC,VIRMA,ROCK1,UBB,CTTN,TNFRSF1B,STUB1,PTEN,CMBL,CYTH1,CRHR1,AP2A1,RPL7A,CSK,AKT1,STK38L,PTHLH,CFL1,RPS17,ATP5F1A,HNRNPK,THRAP3,GNMT,CYTH2,TCOF1,MAP1B,CCR5,RAB1A,IGF1R,RPL3,TP53,RPL15,H2AX,MAP2K3,GRM1,ARF6,KCTD3,TMPO,DKC1,MDM2,ALYREF,TIAM1,KIAA1143,PTGER4,FGR,BRD3,RPS2,CSNK2A1,GNG2 |
| 7.860e-04 | -7.15 | APC-Cdc20 mediated degradation of Nek2A | REACTOME pathways | R-HSA-179409 | 25 | 16 | 10285 | 3229 |
BUB3,RPS27A,CDC26,UBA52,ANAPC11,MAD2L1,UBB,ANAPC16,NEK2,ANAPC4,UBE2D1,CDC16,CDC23,ANAPC15,CDC20,ANAPC2 |
| 7.923e-04 | -7.14 | regulation of protein import into nucleus | biological process | GO:0042306 | 58 | 29 | 18204 | 5365 |
IFNG,MAVS,SMAD3,CHP1,JAK2,HCLS1,EP300,RAB23,SUMO1,HYAL2,CD36,EFCAB7,DMAP1,SUFU,ANGPT1,CDK1,BAG3,JUP,PIK3R2,HDAC3,PIK3R1,RAN,PKIG,RBM22,LEP,PSEN1,UFM1,PKIA,HSP90AA1 |
| 7.942e-04 | -7.14 | positive regulation of interferon-alpha production | biological process | GO:0032727 | 24 | 15 | 18204 | 5365 |
IRF3,TLR8,NMBR,TLR4,TBK1,IRF7,TLR7,RIGI,IFIH1,TLR9,STAT1,MAVS,DHX9,HSPD1,TLR3 |
| 7.942e-04 | -7.14 | release of cytochrome c from mitochondria | biological process | GO:0001836 | 24 | 15 | 18204 | 5365 |
BCL2L1,CLU,MCL1,BOK,TP53,BCL2A1,SFN,FIS1,GGCT,BAK1,BAX,PMAIP1,IFI6,BAD,SOD2 |
| 7.942e-04 | -7.14 | dendritic cell migration | biological process | GO:0036336 | 24 | 15 | 18204 | 5365 |
CCR5,CXCR1,EXT1,HMGB1,CCL5,CCL21,EPS8,CDC42,PIK3CG,CCR6,CCL19,CCR1,CXCR4,CCR2,CCR7 |
| 7.949e-04 | -7.14 | nuclear DNA-directed RNA polymerase complex | cellular component | GO:0055029 | 99 | 44 | 19108 | 5553 |
TAF11,TADA3,GTF2F1,TAF5L,GTF2E2,POLR2F,TAF10,POLR3B,GTF2A1,POLR3F,PRIM2,POLR1H,GTF2H4,MNAT1,POLR2D,SKIC8,CDC73,TAF9,GTF2B,GTF2E1,GTF2H2,ENY2,PAAF1,POLR3GL,POLA2,POLR2G,TAF7,CCNH,MCM3,GTF2H5,POLR1B,GTF2F2,GTF2A2,POLR2I,TAF2,ERCC3,POLR1D,POLR2L,TCEA1,CDK7,POLR2B,SUPT3H,POLR2C,POLR3H |
| 7.958e-04 | -7.14 | FAM241B (family with sequence similarity 241 member B) | protein interactions | 219738 | 88 | 39 | 19454 | 5460 |
ZDHHC15,MOSPD1,TYROBP,REEP6,KCNJ10,ATP1B3,CGRRF1,PRRT1,FAM241A,TM4SF20,SCN3B,TMEM208,SUSD6,APLNR,TMEM170A,ARL6IP5,REEP4,SYNE4,RETREG3,HSD17B11,S1PR4,CD63,GPR35,HCST,BLCAP,TPRA1,ATP5PB,CCDC47,CHRM3,CCR3,SLC7A1,RNF5,LPAR1,LPAR2,VIPR1,RTN4,TMX2,TSPAN15,ADRA1A |
| 7.958e-04 | -7.14 | RGPD5 (RANBP2 like and GRIP domain containing 5) | protein interactions | 84220 | 88 | 39 | 19454 | 5460 |
KPNA2,B2M,VPS28,LGI1,TFPT,DCTN3,MIA2,DISC1,EXOC3,TMEM31,FAM136A,COMTD1,ATG16L1,NUP62,RFXANK,MLLT6,TRIM35,EEF1AKMT3,RAN,TRAF3IP3,CRYBB3,S100A6,PSMC5,PSMD10,BICD2,PSMD7,NR2E1,CCDC92,TSNAX,MAPRE1,COP1,MED4,FGFR1OP2,UBXN6,MLF1,USP14,HSPB8,BTF3,INSYN1 |
| 7.959e-04 | -7.14 | DTX3 (deltex E3 ubiquitin ligase 3) | protein interactions | 196403 | 105 | 45 | 19454 | 5460 |
XRCC5,ARPC2,UBE2D3,UBE2K,RPL4,ZDHHC17,SPTBN1,UBE2W,NOTCH2,SLC25A3,PARP2,RAN,DLST,EFHD2,GANAB,UBASH3B,ATP5F1B,YES1,UBE2L3,RNF141,APEX1,ZMYND19,CUL3,RPL7A,ATP5F1A,BAG3,TUFM,UBE2E3,HSP90AA1,UBE2H,TRIM21,RPS13,TP53,EEF2,UBE2V1,NDUFS6,PARP11,RPL12,RAC2,RPL7,CIAO3,UBE2E2,USP2,HNRNPA1,UBE2D1 |
| 7.959e-04 | -7.14 | PTPA (protein phosphatase 2 phosphatase activator) | protein interactions | 5524 | 105 | 45 | 19454 | 5460 |
PTEN,STAT1,DDAH2,SRC,AKT1,GPRASP3,RACGAP1,CCT2,NIF3L1,SP1,CYP17A1,PRKCB,STK26,TERT,PPP2R3A,USP8,LAP3,BRINP1,SLC25A3,PPP2CB,IER3,IGBP1,TCP1,MDM2,CAV1,CCT7,MOV10,PIK3R1,HDAC6,CSNK2A1,CTNNB1,AGR2,CCT8,OLA1,RIGI,CCT5,H2AX,MAP2K3,PPP2R1A,TUBA1A,SPG21,EZH2,ACOT13,PPP4C,DTD1 |
| 7.960e-04 | -7.14 | positive regulation of DNA biosynthetic process | biological process | GO:2000573 | 71 | 34 | 18204 | 5365 |
RFC2,PTGES3,NEK2,WRAP53,RGCC,CYP1B1,PRKCQ,HTR2A,HSP90AA1,CCT5,KLF4,TCP1,TNKS2,GREM1,CCT8,CCNA2,CCT7,XRCC5,PARM1,TNF,RFC3,CCT2,DKC1,HNRNPA1,MAPKAPK5,RFC4,TNKS,PKIB,HSP90AB1,PCNA,CTNNB1,MYC,RFC5,NEK7 |
| 7.981e-04 | -7.13 | regulation of DNA metabolic process | biological process | GO:0051052 | 515 | 185 | 18204 | 5365 |
MYC,BAX,IL6,IER3,TOM1L1,IGF1R,CDC42,MCM6,HNRNPA1,PHF13,HCRT,KPNA1,PPP4C,HSP90AA1,PELI1,SMARCE1,SLX1A,ACTL6A,HTR2A,MPV17,FOXP3,CDK1,SSBP1,DMAP1,UCN,H1-10,TADA1,HSP90AB1,BABAM1,CD28,LIG3,RMI2,SUPT7L,RUVBL2,MAD2L2,SMG5,TNKS,MEAF6,S100A11,MIR146A,TNKS2,PPP1R10,SMARCD3,ZMPSTE24,TAF2,RGCC,UBE2B,BRCA1,IL4,TAF5L,FGF10,CTNNB1,SHLD1,PCNA,ZBTB38,DKC1,PARM1,ENY2,RFC3,KLHL15,SIRT7,RADX,STAT6,RNF8,CREBBP,CCT7,GREM1,INO80E,RFC2,UBE2V1,UBE2V2,CHRAC1,CDC7,GMNN,AKT1,AIFM1,DHX9,ORC5,STPG4,NUCKS1,HNRNPC,RNF126,SMCHD1,ATF1,CCT2,MORF4L1,PKIB,KDM1A,ING5,MSH6,MIR221,IL2,UBE2N,HNRNPAB,SF3B5,TNFSF13,SUB1,RGN,CSNK2A1,TADA3,NDFIP1,VPS72,NEK7,MCM4,ACTL6B,TAF7,TAF10,DYNLL1,TP53,KLF4,HNRNPA2B1,POLE3,TFPT,JADE1,DNAJC2,MCM3,EYA3,FGFR1,PTGES3,H1-3,MGMT,SRC,SMARCA5,WRAP53,FAF1,PRIM2,EXOSC3,NSMCE3,HMCES,KPNA2,SMARCB1,TCP1,DEK,TFIP11,NIBAN2,CCT5,CCNA2,NBN,ACTR2,CDKN1B,DCP2,PRKCQ,HNRNPD,RFC5,TAF9,KMT5B,RUVBL1,H1-1,RPA2,TFRC,RPS3,ACTB,ADIPOQ,TNF,IL10,STN1,SGF29,CCT8,TOP2B,BCL7B,HMGB1,DFFA,INO80C,BCL6,CD40,H2AX,TNFAIP1,CGAS,SUPT3H,ZNF365,OGG1,NPPC,FAM168A,CDK9,MAPKAPK5,RFC4,PML,CDKN1A,H1-5,BCL7C,XRCC5,NEK2,H1-6,CEBPG,CYP1B1 |
| 8.023e-04 | -7.13 | SOLCAR | prosite domains | PS50920 | 53 | 26 | 12186 | 3388 |
SLC25A27,SLC25A44,SLC25A21,SLC25A39,SLC25A3,MTCH2,SLC25A26,UCP2,SLC25A1,SLC25A17,SLC25A12,SLC25A46,SLC25A45,SLC25A10,SLC25A42,SLC25A4,SLC25A11,SLC25A5,SLC25A51,SLC25A31,SLC25A20,SLC25A24,SLC25A23,SLC25A28,SLC25A14,SLC25A32 |
| 8.027e-04 | -7.13 | cellular response to metal ion | biological process | GO:0071248 | 185 | 75 | 18204 | 5365 |
NEUROD2,BACE1,FBP1,SLC25A23,PRNP,MT1X,DLG4,CER1,MT1E,ATF4,JUN,JUNB,HSPA8,HFE,AKT1,CREB1,MEF2A,ADD1,HPCA,CRHBP,SLC1A1,TF,MMP9,MT3,NEK7,UCP2,SLC13A5,KCNB1,DPEP1,CYP11B2,NLGN1,CALR,KCNJ10,GLRA1,CLIC4,CLDN1,CPNE1,MT2A,BECN1,NPTX1,HSD17B1,PPIF,FABP4,CYP1A1,CDKN1B,TSPO,TLR9,NQO1,SLC12A2,MTF1,MAP1LC3A,GSK3A,B2M,NCSTN,SLC25A24,EIF2S1,MT1M,TUBA1A,OGG1,SLC41A1,KCNH1,ALOX5AP,SUMO1,MEF2C,CYP11B1,MCOLN1,NFE2L2,FOS,RASGRP2,MT1A,MECP2,HSP90B1,AQP2,GLRA2,CPNE2 |
| 8.042e-04 | -7.13 | CGAS (cyclic GMP-AMP synthase) | protein interactions | 115004 | 267 | 99 | 19454 | 5460 |
KIF2A,CHMP4C,TRIP4,FLOT1,MRPS17,MX2,TRIM26,TOR4A,RAB5C,MRPS35,IFI16,BAZ1B,RAB32,HSPB1,MAGOH,VPS4A,MRPS26,SKIC8,GJA1,TSG101,MRTO4,SDC4,IFIT2,CHMP2A,VAMP7,ZNF593,LYAR,NOB1,PIP4P2,APOBEC3C,APPBP2,MRPS7,UFL1,F2,NOP16,MYC,ILK,NSA2,CTSK,BRCA1,FTSJ3,MRPS25,LAMTOR1,BLVRA,PARP2,APOBEC3G,RPL7L1,TAX1BP1,APOBEC3D,MRPL47,NUPR1,SRP72,RAD23B,RBM34,LLPH,MRPS18B,ABCE1,NKRF,EHD4,VTA1,RAB3B,APOBEC3F,SPATS2L,TUBG1,KRR1,MRPS9,MRPL24,SURF6,MRPS23,CGAS,PRNP,CNP,MX1,MACROH2A2,STOM,CHMP1A,ZCCHC17,VPS4B,SDCBP,MRPS34,SQSTM1,GREM1,PNO1,VPS28,PIP4P1,CHMP2B,MRPL41,SLC25A1,SMARCA5,MAPRE1,ASCC1,MACROH2A1,MRPS28,SEC61A1,PRKRA,PELP1,VIRMA,CHMP5,ZNF622 |
| 8.049e-04 | -7.12 | MME (membrane metalloendopeptidase) | protein interactions | 4311 | 134 | 55 | 19454 | 5460 |
FAHD1,CD4,NDUFB4,ACSL4,PRNP,RPS10,HNRNPL,TENM3,RAP2B,CSNK2A1,EMC4,PIK3R1,HSPB1,TMEM164,SHC1,CDK5RAP3,EMC2,PCNA,RUVBL2,SLC16A1,TMT1A,ADD2,RUVBL1,EEF1A1,RPS23,KBTBD3,NHERF1,PTEN,CSNK2B,B4GALT1,CYB5R3,VDAC2,ESR2,NPPC,MGAT1,AR,GLT8D2,RAB11A,ZMPSTE24,MRPS25,LAMTOR1,MTDH,HSPA8,VIP,XRCC5,SNRK,MME,PXMP2,NUCKS1,EMC1,FAM234A,LEMD3,TM9SF1,UBAC2,LMNA |
| 8.075e-04 | -7.12 | positive regulation of immune effector process | biological process | GO:0002699 | 261 | 101 | 18204 | 5365 |
SASH3,IL18,MIF,BCL10,HTR2A,HSPD1,FOXP3,IL12A,HSPA8,LILRB1,PHB2,MICB,CD1A,NECTIN2,TLR4,IL17F,TLR3,CD1E,FGR,IL12B,IFNG,DDX1,IL6,CLEC7A,RSAD2,IL21,CD86,IL13,TLR9,SOCS5,MYD88,IL4,SH2D1A,CD46,MIR21,CD81,MAD2L2,TYROBP,TICAM1,RIGI,HMCES,MAVS,IL23A,CD80,CD28,CD36,B2M,SEMA7A,EXOSC3,CD1D,SYK,MBL2,VAMP8,HFE,IL1B,CD40,NCR3,KLK3,STAT6,PYCARD,STAP1,CD226,MZB1,EP300,TNF,FCN2,XCL1,IL10,KLRC2,KMT5B,SHLD1,TRAF2,KLK5,VAMP7,TFRC,PHB1,TRIM6,TNFSF13,XBP1,NLRP3,TRAF6,KIT,CD1C,CD1B,VAMP3,CCL19,CCR2,IL2,DNAJB9,CYRIB,KLRD1,IL5,TNFRSF14,STXBP1,TLR7,SPHK2,STX7,PLA2G5,LTA,LACC1,FCGR1A |
| 8.087e-04 | -7.12 | endoplasmic reticulum to Golgi vesicle-mediated transport | biological process | GO:0006888 | 131 | 56 | 18204 | 5365 |
TRAPPC6B,SAR1B,CIDEB,TFG,BCAP29,TRAPPC3L,KDELR1,TRAPPC4,TEX261,TRAPPC6A,RAB1A,TRAPPC10,USE1,TMED5,LMAN1,CUL3,BET1,YIF1A,TMED3,TRAPPC1,YIPF4,YIPF5,TRAPPC3,SCFD1,STX17,ARCN1,COPE,VAPB,STX5,KLHL12,SEC23A,VAMP7,YKT6,GOSR1,SEC13,KDELR2,GOSR2,SEC22C,SURF4,RAB2A,SEC22B,RAB29,RAB1B,TMED1,RINT1,SEC22A,TRAPPC13,RANGRF,TRAPPC2L,TMED9,ARF4,CNIH4,MIA2,TMED4,PREB,TMED7 |
| 8.113e-04 | -7.12 | MFSD4A (major facilitator superfamily domain containing 4A) | protein interactions | 148808 | 224 | 85 | 19454 | 5460 |
JAK1,RUSF1,FKBP8,GOLGA7,SACM1L,RAB18,PSEN1,FASTKD5,CSE1L,TUBA1A,MAP2K3,IPO8,ARFGEF1,CCDC47,SLC25A24,DHRS7B,VAC14,UCK2,KDELR1,ACADSB,SURF4,C2CD2,XPO5,SLC39A10,DECR2,CD63,MPDU1,ACTA2,COQ8A,SRPRA,MSMO1,CYSTM1,DERL2,ATXN10,COG1,CAND1,ECHDC1,MZT2B,XPO1,SEC61A2,EI24,SYNJ2BP,VPS4A,HAX1,AREL1,PEX3,TMEM126B,TMEM263,RAB29,TMEM209,RER1,MFSD3,CYFIP2,SLC7A1,SLC35E1,MTX2,SEC22B,COQ8B,TOMM22,SYNGR2,FDFT1,TM9SF1,SAMM50,SIGMAR1,STX17,PTPMT1,CHCHD6,DTYMK,SMAP2,CHRM4,CHP1,TNPO3,ATP6AP2,ARMC6,LGALS3,DHRS13,SLC25A4,STAT1,PYCR2,CIAO1,VMP1,XPOT,FIS1,PSMD14,ATP1A3 |
| 8.113e-04 | -7.12 | U2AF1 (U2 small nuclear RNA auxiliary factor 1) | protein interactions | 7307 | 224 | 85 | 19454 | 5460 |
FTSJ3,UBE2H,RIT1,THOC6,RRP7A,CUL3,CFAP20,MYC,NDN,SRPK2,SMURF1,RAN,TUBA1B,CCNF,VEGFA,SF3B6,PLP1,PTEN,RPL37A,GSK3A,SNRPD2,SNRPD1,GRM2,RPA2,HEXIM1,MFAP1,SF3A1,RPS14,FBXW7,TRA2B,SRSF2,AATF,SAP18,PRPF4,BAP1,RNF113A,DDX5,SF3B1,NMRAL1,H2AC4,SNRNP70,DDX23,TSNAX,RPS2,WWP2,ZCCHC10,FRA10AC1,PRPF19,SUV39H1,VPS26C,SNRPA1,NKAP,NOP58,CAND1,FZR1,CDC5L,PHB1,SRSF1,FOLR1,SYNCRIP,IK,EZH2,RP9,NUPR1,ZRANB2,DHX38,RAF1,FBP1,HINFP,RPL15,RPS7,NCSTN,HNRNPK,KRAS,G3BP1,RPS4X,MEPCE,RPS13,PABPC1,MAP1B,DHX9,RPS24,SRSF7,SEPTIN7,EWSR1 |
| 8.117e-04 | -7.12 | COX8A (cytochrome c oxidase subunit 8A) | protein interactions | 1351 | 320 | 116 | 19454 | 5460 |
EDDM3B,PSMC4,MRPL10,SLC12A2,QRSL1,COX6C,MRPS34,MTRES1,CYC1,GFM1,DLAT,TWNK,MRPL40,PDHB,NME4,YKT6,POLDIP2,MRPL20,GRPEL1,PYCR2,NDUFAF2,PPP1CC,DEPDC1B,ATP5F1A,MRPS16,MAPRE1,OAT,ATP1A1,VAMP3,ACAT1,PTPMT1,PSMC5,MRPS28,SLC25A4,MGST3,BATF,IPO8,NAA35,BCS1L,METTL15,HADH,PPIF,ACADSB,MAGEA4,NDUFS3,TFRC,HSD17B10,SNAP23,HSPE1,NUP107,PDE12,ABHD10,RIGI,FASTKD5,MRPL22,SLC6A8,MEPCE,COX5A,TMEM199,GRSF1,LYPLAL1,HM13,TRMT5,MGME1,COX4I1,SSBP1,MRPS9,MRPL50,SURF6,MRPL24,MRPS23,SLC38A2,DBT,MRPL12,QTRT2,IDH3B,NGRN,HADHA,ATP5IF1,PHB2,NDUFS2,MRPS7,PYCR1,PMPCA,NOA1,LAMTOR1,ZMPSTE24,SLC38A1,VDAC2,TACO1,TRMT11,ATP5F1B,NDUFAF4,HSDL2,PDHA1,CFAP36,KDELR1,NDUFS6,VAMP2,NDUFA12,THNSL1,NDUFA4,PREPL,SLC25A5,MRPS11,HINT2,ETFA,KGD4,COX7B,MRPS35,STOML2,CLPX,CTNNB1,MRPS26,SIN3A,PNPLA8 |
| 8.119e-04 | -7.12 | G protein-coupled chemoattractant receptor activity | molecular function | GO:0001637 | 26 | 16 | 18094 | 5411 |
CCR2,GPR17,GPR75,CCR3,ACKR3,CCR1,CCR7,CCR6,CXCR6,CXCR4,CXCR1,CXCR3,CX3CR1,CCR4,GPR35,CCR5 |
| 8.119e-04 | -7.12 | chemokine receptor activity | molecular function | GO:0004950 | 26 | 16 | 18094 | 5411 |
CCR6,CXCR6,CXCR4,CCR7,GPR35,CCR5,CXCR3,CXCR1,CCR4,CX3CR1,GPR17,GPR75,CCR2,CCR1,CCR3,ACKR3 |
| 8.120e-04 | -7.12 | regulation of CD4-positive, alpha-beta T cell activation | biological process | GO:2000514 | 79 | 37 | 18204 | 5365 |
CD28,CD80,CBFB,ARG2,IL23A,IL2RG,CD86,VSIR,EP300,IL2RA,TWSG1,RC3H2,IFNG,IL12B,XCL1,TGFBR2,IRF4,IL2,CCL19,CD81,KLHL25,BATF,AGER,MIR21,SOCS5,CD83,RUNX1,IL18,SASH3,HMGB1,JUNB,NDFIP1,CD274,NLRP3,FOXP3,PRKCQ,BCL6 |
| 8.166e-04 | -7.11 | NUP85 (nucleoporin 85) | protein interactions | 79902 | 137 | 56 | 19454 | 5460 |
MAPRE1,RIT1,LMNB1,RUNX1,SEC13,CUL3,APEX1,ESR2,VIRMA,CCR2,PTPMT1,UBE2I,SEC61B,RAN,PELO,LMBR1L,CCNF,LMNA,CDC42,PSMC4,NUP62,UNC45A,COIL,EEF1G,NPTN,TRA2B,B9D2,DCTN3,NUP50,DVL2,CD40,PIK3R1,IFI16,CETN2,HSP90AB1,ZNF740,EED,RCHY1,CD274,PTPN1,NUPR1,HDAC11,EZH2,CA14,NUP37,PPP2R1A,NUP153,FAF2,RANBP1,TOP3B,COMTD1,PSMB10,NUP107,KRAS,EFNB1,HAPSTR1 |
| 8.187e-04 | -7.11 | FXR2 (FMR1 autosomal homolog 2) | protein interactions | 9513 | 418 | 147 | 19454 | 5460 |
LDOC1,CCR4,AATF,BAP1,RPA3,SIRT7,TRIM3,LSM12,TNFAIP1,RTN4,EGFL7,MTDH,RNF113A,RPA2,ZCCHC17,RPLP0,DCTD,CCN3,AGO1,ZSCAN1,FTH1,NDN,YES1,SRPK2,PSPC1,CCNF,EIF2AK2,GSK3A,RTRAF,CSNK2B,RPS20,MECP2,NIF3L1,TRIM23,BICD2,RC3H2,NRP1,UBE2H,MORF4L1,PYCR2,NONO,PCBD1,CAMK2G,RPIA,RIGI,ZNF451,PSME1,SNAP23,TFCP2,NUPR1,SPRY1,FBP1,TBK1,YTHDF2,THAP1,FZR1,CAND1,RPS16,RBM42,LCP2,ZBTB2,SLAIN2,AIFM1,PDE9A,COMT,LCMT1,CCDC92,H2AC4,SNRNP70,RPS2,TSNAX,KXD1,GRSF1,CSNK2A1,HDAC6,MPG,FXR2,UFL1,CYFIP2,YTHDF1,PITHD1,STAU1,COIL,RNF41,G3BP2,RABAC1,USP39,LARP4B,NUFIP2,MFAP1,WDR77,GKAP1,RALYL,TRIM29,ESR2,PRRC2A,PNMA1,CMTR1,AP2M1,ZMAT2,RBBP8,BRCA1,LSM14B,MYC,HNRNPC,CUL3,BTF3,CCDC85B,G3BP1,LASP1,TRIM37,DCTPP1,AP1M1,BCKDK,LSM14A,ZC3H7A,EWSR1,PICK1,RTCB,GLE1,NME1,AAMP,RAF1,TOP3B,PTS,TRAF2,KIF2A,OCRL,DPPA2,FAM98A,MEAF6,MPP1,SNX1,CCAR2,DNM2,FUBP3,HOMER3,DDX1,HSPB1,CNOT2,DDX50,IFI16,WWP2,YWHAH,NT5C2,DDRGK1,MAP3K14 |
| 8.190e-04 | -7.11 | Transport to the Golgi and subsequent modification | REACTOME pathways | R-HSA-948021 | 164 | 71 | 10285 | 3229 |
TRAPPC2L,B4GALT3,BET1,SEC13,TMED7,B4GALT6,COPE,SERPINA1,TRAPPC4,STX5,COG1,GOSR1,SPTBN1,CNIH1,MIA2,YKT6,CHST10,MAN1A2,TMED3,DCTN3,NAPG,MIR711,SAR1B,SCFD1,ARCN1,SPTAN1,CTSC,DCTN4,ARF1,TRAPPC3,RAB1B,RAB1A,TMEM115,NAPA,FUT8,GRIA1,STX17,DYNC1I2,MGAT1,KDELR2,ST6GAL1,TRAPPC6A,DYNLL1,LMAN1,MGAT4B,TRAPPC6B,LHB,DCTN6,SEC23A,BET1L,GOSR2,PREB,SEC22A,KDELR1,TFG,B4GALT1,SEC22B,MGAT4A,TMED9,COPZ2,CD59,ARFGAP3,TRAPPC10,B4GALT4,TRAPPC1,SEC22C,ARFGAP1,DYNC1I1,ARF4,ST3GAL4,FOLR1 |
| 8.223e-04 | -7.10 | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological process | GO:0051896 | 270 | 104 | 18204 | 5365 |
EPHA2,NOP53,CCR7,PRR5L,RGL2,SEMA5A,NKX3-1,DRD3,MTDH,STK11,TNF,IGF1,SIRT7,MUL1,CRYBA1,TGFB2,CX3CL1,MIR675,PIK3AP1,HYAL2,CX3CR1,MIR145,TXN,GH1,SESN3,GPX1,PHB1,INPP5E,DDR1,CCL21,MIR20A,HCST,CBL,NDP,SOX9,KIT,MIR206,F2,CCL19,GRM2,BECN1,DLG1,CHI3L1,JAK2,HCLS1,MIR29C,PTEN,PIP5K1A,NHERF1,RAMP3,CCL3,IL18,FGFR1,ANGPT1,SRC,DAG1,INPP5K,MIR34C,MIR449A,BTN2A2,HAX1,LEP,DDIT3,STK3,RNF41,PIK3CG,PPARA,TMEM100,DIPK2A,CCL5,PIK3CA,MIR34B,UBE3A,FGR,MIR126,IGF1R,FLCN,P2RY12,STAMBP,FERMT2,MIR34A,CDC42,RTN4,OSM,SESN2,PPP2R1A,NTRK2,CPNE1,NTRK3,MIR375,MTM1,MIR146A,HBEGF,MIR21,C1QTNF1,TPBG,AKR1C2,VAV2,CD28,MYORG,MSTN,CAV3,OSBPL8,MIR29A |
| 8.247e-04 | -7.10 | XRN2 (5'-3' exoribonuclease 2) | protein interactions | 22803 | 361 | 129 | 19454 | 5460 |
MRPS9,SYNCRIP,COMT,RCHY1,MBD5,CDK9,CDC5L,MRPS23,PLEKHF2,CAND1,FZR1,MRPL50,HDAC6,COPS5,CSNK2A1,API5,MOV10,RBM17,KPNA1,LSM3,CLP1,SNRNP70,MRPS18B,SNIP1,NKRF,MEPCE,MRPL22,SMN1,CTSC,CDC40,REXO2,TOLLIP,NOC4L,HNRNPK,EEF1A1,EXOSC8,STRBP,MRPL47,TP53,ILF2,NUPR1,DXO,DISC1,CCNF,PSPC1,EIF2AK2,ENO1,ZNF330,SRPK2,RUNX1,KPNA6,AR,CARS1,CDKN2AIP,UBE2H,RC3H2,EXOSC4,RNF113A,PRIM2,RPA3,SIRT7,ARHGEF6,AATF,WDR3,CCL3,GTF2H4,ATG16L1,HEXIM1,UTP15,TFB1M,MRPS34,RPA2,RPRD1B,GRM2,MAGED2,COPS2,SRSF1,CHMP2A,DHX15,HNRNPL,CCAR2,SNRPD3,CPEB1,HNRNPA1,XPO1,DDRGK1,IFI16,WWP2,MRPS35,MRPS26,MPHOSPH6,DDX23,AGR2,RPS24,SRSF7,RPL31,HNRNPA2B1,UBE2A,COPS4,KRAS,ASF1A,RBM12,SPC24,HEXA,SSBP3,EZH2,PSMB6,POLR2B,APEX1,USP16,SNRNP40,BTF3,TTC23,MYC,HNRNPAB,CUL3,HNRNPC,PSKH1,BRCA1,ATG3,HSPA8,EP300,PSMA3,UPF3B,MRPS7,UFL1,TRA2B,ARHGEF39,YTHDF1 |
| 8.259e-04 | -7.10 | TMEM220 (transmembrane protein 220) | protein interactions | 388335 | 8 | 7 | 19454 | 5460 |
TMEM14B,LRRC3B,SRC,PACSIN3,COX6B1,ACTA2,PTPN11 |
| 8.259e-04 | -7.10 | OR10H3 (olfactory receptor family 10 subfamily H member 3) | protein interactions | 26532 | 8 | 7 | 19454 | 5460 |
LASP1,NME2,PAK2,IRGQ,HMGCS1,CYB5A,FAHD1 |
| 8.267e-04 | -7.10 | RNF34 (ring finger protein 34) | protein interactions | 80196 | 50 | 25 | 19454 | 5460 |
KLHL15,MAVS,RNF34,HSPA8,APPBP2,RIGI,UNC119B,TSR3,UBE2D3,CHCHD2,MSX2,SUPT4H1,SUPT5H,TP53,UBE2F,EFCAB7,ANAPC2,CDC20,MANSC1,TAX1BP1,FZR1,OST4,UBE2H,PHF7,TRIM23 |
| 8.267e-04 | -7.10 | SNX12 (sorting nexin 12) | protein interactions | 29934 | 50 | 25 | 19454 | 5460 |
LAMP3,LAMP2,LAMTOR1,MTAP,IGBP1,EIF4A3,MIDEAS,RPRM,CDC5L,PEG10,UBE2L3,SNX3,TAGLN2,PPIL3,TP53,ATG16L1,HGS,AKR1A1,GNPDA2,TAGLN3,RTN4,PPM1G,CDC42EP4,AHCYL1,PSMC1 |
| 8.267e-04 | -7.10 | regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050730 | 220 | 87 | 18204 | 5365 |
EPHA4,TP53,IL12B,DUSP22,IFNG,OSBP,IGF1,MIR106B,ADIPOQ,TNF,CCL5,IL13,YES1,LACRT,GH1,FGF10,IL6,HYAL2,IL21,SFRP1,HTR2A,PTPN1,SRC,IL12A,GHR,RAP2C,ERRFI1,CD40,ANGPT1,SYK,FGF7,RAP2B,IL18,CSH1,MIF,TNFSF18,GREM1,DLG4,LEP,HAX1,SOCS4,CSF2,FBXW7,IL6ST,PRNP,PTPN11,ARL2BP,CLEC6A,IL34,NRP1,CNOT7,IL5,TNFRSF14,SOCS3,JAK2,EPO,HCLS1,CAV1,TSG101,IL15,IL7,FCGR1A,NF2,ADNP,ZNF592,EFNA5,IL3,IL23A,PRKCE,CD80,VEGFA,CD36,IL4,ACVR1,KIT,CBL,OSM,SOCS5,CD4,HBEGF,DLG3,MIR146A,LILRB4,PAK2,MIR221,EHD4,IL2 |
| 8.276e-04 | -7.10 | APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1) | protein interactions | 328 | 1256 | 402 | 19454 | 5460 |
COIL,TGFB1I1,LZTFL1,NMRAL1,NUBP2,NUP50,PMAIP1,SLC35F2,RNF10,THOC3,TBC1D17,PSRC1,NPY2R,WDR77,TMCC1,TSN,EIF3K,WDR20,MYO6,IKZF2,CUL2,AP1M1,RFC2,TRIM26,G3BP1,H19,ZBTB14,SLC39A7,MORC2,PLSCR1,GTF2E2,FEN1,KHDC4,TXNRD1,CGGBP1,CNTROB,NOP58,SGMS1,HP1BP3,THOC2,FAM3A,RSBN1L,ADAT1,UBE2D1,DDX23,ATG7,NKIRAS1,UBXN6,PRPF19,RPL4,TMEM126B,ABCB9,AMACR,CCSAP,TMOD1,JUP,CLSTN3,PSMC4,TPT1,TXN,WDR45,PRKRA,RPS20,TRIM24,UBE2I,STUB1,BMERB1,XPOT,ZNHIT3,NTAQ1,ATP5F1A,CAP2,CTSD,CAMK2G,THRAP3,TEDC2,APEH,RAD23B,CASK,ZFAND2A,POMT2,CTDSP2,SLC29A1,COMTD1,MAPRE2,EIF2B5,CDCA3,CTDSPL2,H2AZ1,TOPBP1,CRBN,HDAC6,EMC4,HSPA8,EP300,SLU7,FLYWCH2,XRCC5,OSR2,KLC2,PIH1D1,UBAC2,ZNF362,NEK7,VAMP1,NUP62,ATP6AP2,CLVS2,GTF2F1,GTF2F2,ZNF189,POLR1B,DNAJB6,MAF1,TFDP2,FTSJ3,S100PBP,MLF2,TBCE,PAPOLA,POLDIP3,TOP2B,RBM3,PABPC1,SDHC,ADCY3,RAB4A,TRAF2,SUPT5H,PGS1,TCP1,DYNC1I2,LYAR,RFX5,TRAPPC10,CEP57L1,HOMER3,SMAD9,R3HDM4,AGR2,SLC38A9,SIVA1,CIAO3,KDM1A,RNF113A,PRDX6,BTBD10,BANF1,STAT6,RPA2,WRAP53,USE1,XBP1,CREBZF,SPTBN1,SRPK2,BUB3,PSMC5,PAFAH1B3,GCFC2,LIG3,GZMK,DNAJC10,TNFAIP3,CYTH2,IMP4,RPL3,ABCE1,NAE1,SAPCD1,CHAMP1,IK,NFE2L2,ACTR1A,ZMYM4,SRFBP1,DKC1,SURF6,MCL1,CD274,AGPAT1,SMAD4,POLB,SSBP4,CSNK2A1,TSEN34,ZNF24,NOP53,RADX,TERT,ATP2C1,EXD2,ELOVL1,MFAP1,FKBP1A,NUDT3,SUPT4H1,CDKN1A,ACTL6A,PRR5L,PAOX,PRRC2A,EIF4A2,TRIM46,REEP4,ACTB,SNRPD1,AP1G2,GPR89A,SCFD1,ILK,FYTTD1,BRCA1,OCEL1,JPT1,PRPF31,CAPG,TM2D2,PKP4,GOLGA7,FLOT1,ENKD1,RAD21,DHX16,PCNA,PLCB1,SLC25A5,GADD45A,DTWD2,SART3,BZW2,RAB6B,NME1,OTUD6B,GABARAPL1,JUN,NFE2L1,ANP32A,BUD23,NEU1,SLMAP,KRT8,STX1A,ST3GAL4,DROSHA,HNRNPA1,HMGA1,ATG9A,MEF2A,VPS28,NF2,RPA3,HELLS,RARS1,KRT7,SH3GLB2,NUDT12,PICALM,METTL14,DDAH1,SCML2,FERMT2,GNAI2,VIRMA,DEK,PPM1M,MSN,GAB1,CTTN,TUBA1B,HERC4,ZSWIM7,FBXO7,RACGAP1,DNAJC8,NAA60,PPP1R12A,SIKE1,TCOF1,NKRF,RNF167,VAC14,FAM169A,MAP2K3,TRIM6,MDM2,NKIRAS2,ANKRD46,TES,DNAJC4,BRD3,POR,KIAA1143,GOSR1,TRA2B,DR1,DDX5,SMARCD3,INSYN2A,TBCEL,TIMM10,DUSP14,ZC3H14,ESR2,ACAP2,APEX1,TAMM41,MATR3,SSH3,TAX1BP1,PRMT5,PAPSS2,VEGFA,CMTR1,KIAA1191,CIRBP,ST3GAL1,MYC,HNRNPC,DCTPP1,SLC35A2,CCAR1,HNRNPF,ROCK2,LDLRAD4,EWSR1,PRDM4,LSM14A,APTX,MIR222,FOXJ3,MIEF1,GCLC,HEXA,TCF21,CCT7,SMUG1,HNRNPL,SSR2,UBFD1,MIR221,H2BC17,RIMKLB,BAZ1B,DDX50,ASB1,SEC61A2,ZCCHC10,UGP2,CLDND1,BCL6,HDAC3,NME4,FTSJ1,ADAMTS10,DPAGT1,BAP1,TEX264,IRF3,PML,FGFR1,CDC42,SNX22,MPV17,CTSB,DAPK3,PLAGL1,PITPNB,CYTH1,MACROH2A1,NECTIN2,FAM210A,TBC1D25,UBE2H,MECP2,NIF3L1,SNX14,CFL2,RPL7A,NUDT1,PHF1,PDE12,HNRNPK,CLPB,YIF1A,PSME1,SURF4,DXO,STRBP,TP53,RPSA,R3HCC1,CPNE1,FZR1,MTAP,KPNA1,SMCHD1,AMY2B,FCGR2A,RPAIN,ELOC,ENY2 |
| 8.290e-04 | -7.10 | ZBTB49 (zinc finger and BTB domain containing 49) | protein interactions | 166793 | 25 | 15 | 19454 | 5460 |
ZBTB17,PSD2,UTP25,ZBTB2,PICK1,EP300,EZH2,HSP90AA1,VAC14,WDR83,HINFP,TP53,DDX39A,TRAF2,CEP70 |
| 8.290e-04 | -7.10 | PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5) | protein interactions | 57449 | 25 | 15 | 19454 | 5460 |
RND3,YWHAB,FBXW11,YWHAZ,GNG2,YWHAH,RND2,TOMM40,YWHAG,TOP3B,LNX2,GNB4,AHCYL1,APEX1,VDAC2 |
| 8.290e-04 | -7.10 | SENP7 (SUMO specific peptidase 7) | protein interactions | 57337 | 25 | 15 | 19454 | 5460 |
TULP3,SIAH2,DDX39A,MYL12B,ZCCHC10,SPOP,CSTA,CBX3,CHAMP1,BCL6,APEX1,CBX5,RBBP4,SUMO2,FBXW7 |
| 8.290e-04 | -7.10 | CRIPT (CXXC repeat containing interactor of PDZ3 domain) | protein interactions | 9419 | 25 | 15 | 19454 | 5460 |
MED23,CZIB,CCDC25,MED4,NLRP2,RAF1,ATG16L1,CUL3,DLG3,CCNA2,TUBB,APEX1,THOC2,DLG1,DLG4 |
| 8.290e-04 | -7.10 | HACD1 (3-hydroxyacyl-CoA dehydratase 1) | protein interactions | 9200 | 25 | 15 | 19454 | 5460 |
RPN1,LMNA,TMEM106C,XPO1,HACD2,EDEM2,TECR,GNB1,PHB2,CSE1L,SLC15A1,MYO1B,CORO1C,SEMG2,PHB1 |
| 8.290e-04 | -7.10 | PTGES (prostaglandin E synthase) | protein interactions | 9536 | 25 | 15 | 19454 | 5460 |
SMCO4,VAPB,EHHADH,BET1,TMEM19,CFTR,HDAC6,PTGER2,PLP2,SEC22A,SPPL3,VAMP3,YIF1A,PTGES,PTGER1 |
| 8.291e-04 | -7.10 | TAOK2 (TAO kinase 2) | protein interactions | 9344 | 77 | 35 | 19454 | 5460 |
KLHL12,CTSA,MAP2K3,CDC42,SEC62,TUBA1A,RAF1,TOP3B,PDE2A,KRAS,SQSTM1,HADHA,IGF1R,STK26,BSCL2,ARB2A,LTBR,MAPRE1,MCAT,ABITRAM,PDCD10,STK24,PIP4K2C,H2AC14,TNFAIP3,CIDEB,ESR2,EGLN3,ELK1,TUBB,SEC61B,MAP2K6,RCHY1,LMBR1L,AIP |
| 8.291e-04 | -7.10 | RALB (RAS like proto-oncogene B) | protein interactions | 5899 | 77 | 35 | 19454 | 5460 |
DBT,LAMTOR3,PTEN,XPO5,ARMC1,COX4I1,PHB1,HRAS,EXOC8,EXOC2,AGR2,NONO,EXOC1,MMUT,XPO1,HDAC6,PYCARD,CSK,RALB,EI24,SLC25A1,PHB2,EMC1,EMC2,IRF3,SLC25A5,CYC1,SLC25A3,EXOC3,TULP3,CENPM,IPO8,TBK1,MARCKSL1,RAF1 |
| 8.291e-04 | -7.10 | SDC1 (syndecan 1) | protein interactions | 6382 | 77 | 35 | 19454 | 5460 |
XPNPEP1,CAMKV,PTN,GNB4,RAP2A,EP300,HADHA,PICK1,TXNL1,CCNY,MMP14,SDCBP,SDC2,GNAZ,CASK,CSNK1G3,RAF1,CXCL8,LYAR,ESR2,ZNF593,CD63,PARP2,HRAS,PTEN,CDCA3,PREP,LACRT,CHORDC1,EPHA2,MYC,BAG3,CCL5,FGF1,HMGCS1 |
| 8.356e-04 | -7.09 | regulation of inflammatory response to antigenic stimulus | biological process | GO:0002861 | 48 | 25 | 18204 | 5365 |
TNF,NLRP6,KARS1,FURIN,IL10,IL12B,FGR,MIR105-1,CD28,LTA,GPX1,NPY5R,YES1,GPR17,FCGR1A,IL20RB,SYK,PSMB4,SRC,CCR7,FCGR2B,PSMA1,CNR1,CD81,SELENOS |
| 8.366e-04 | -7.09 | HEXA (hexosaminidase subunit alpha) | protein interactions | 3073 | 91 | 40 | 19454 | 5460 |
HEXB,HNRNPH3,RPRD1B,GTF3C4,H2AX,DHRS4,UBR7,ATG16L1,TOP3B,ARHGAP1,MARS1,G3BP1,XPNPEP1,PCNA,SEPTIN7,NUBP2,RPA3,NUDT5,DNAJC3,TMEM106B,PDCD10,HNRNPD,HERC4,SKIC8,H2BC17,YWHAZ,H2AZ2,HMGCS1,CREBBP,LDHB,CUL3,TRMT61A,ROCK1,CCT7,APEX1,TCP1,ADD1,SYNCRIP,SSBP1,OPTN |
| 8.366e-04 | -7.09 | ATF3 (activating transcription factor 3) | protein interactions | 467 | 91 | 40 | 19454 | 5460 |
NFE2L2,CAPZA2,JUN,EGR2,MAFG,DOK5,TP53,BATF,MEF2A,IGSF21,CAPZA1,HDAC3,EWSR1,HDAC5,DDIT3,FOS,ATF3,SMAD2,HSP90AA1,COP1,HDAC6,SUV39H1,NFKB1,CREB3,CREBBP,MYC,ATF4,MDM2,LRIF1,NR1I2,JUNB,NUF2,STAT1,CEBPE,ACTB,SH2D1A,UBE2I,CEBPG,SMAD3,EEF1B2 |
| 8.366e-04 | -7.09 | MAN1B1 (mannosidase alpha class 1B member 1) | protein interactions | 11253 | 91 | 40 | 19454 | 5460 |
EZH2,CTBP1,GP9,AQP3,PLD3,GNAI3,MGARP,TNFSF8,SLC6A8,IL13,RIGI,TEX264,PML,SLC39A7,SLC39A3,EP300,IGF1R,SPCS3,TRAPPC2L,HNRNPD,IGF2BP1,KCNJ2,RAB2A,RAB5C,EDEM1,COMMD5,GOLPH3L,RANBP6,HNRNPL,RAB1B,PRNP,ESR2,CCNF,ARF1,DNM2,CD79B,LMBR1L,B4GALT1,EED,PTEN |
| 8.366e-04 | -7.09 | PSME4 (proteasome activator subunit 4) | protein interactions | 23198 | 91 | 40 | 19454 | 5460 |
PSMB6,VIRMA,SPPL3,PSMD4,MBL2,PSMD6,ADRM1,PSMC5,PSMB1,PSMA6,PSMB5,PSMB4,SLX1A,SMAD4,PSMD14,COPS5,PSMD1,PSMD3,MYC,PSMB2,PSMA4,PSMC1,PSMD12,PSMA5,PSMA1,SEM1,PSMA2,PSMA3,UBE3A,RPA3,THNSL1,PSME1,PSMC3,SART3,PSMB7,GTF3C4,PSMB9,PSMC4,TOP3B,PSMB3 |
| 8.366e-04 | -7.09 | MICU2 (mitochondrial calcium uptake 2) | protein interactions | 221154 | 91 | 40 | 19454 | 5460 |
TRIM44,AIFM1,MYEF2,CMTR1,LURAP1,ACTA2,COX4I1,SLC1A1,RANBP6,ARMC6,TUBB,ESR2,PARL,SLC25A12,ZCCHC10,CUL3,COPS5,ATG7,LCN6,GPRASP2,KLHL22,CHCHD4,DCAF11,HTRA2,CXCR4,RPA3,SFXN1,AKAP1,YTHDF1,PHB2,SLC25A51,RIGI,IMMP2L,CSNK1E,MGARP,APOO,STXBP1,TIMM8A,RPA2,AQP3 |
| 8.367e-04 | -7.09 | RMC1 (regulator of MON1-CCZ1) | protein interactions | 29919 | 143 | 58 | 19454 | 5460 |
TES,SWAP70,SRPRA,WDR6,AIFM1,ACSL4,DYNC1I2,ATG7,ATG9A,POR,SLC2A1,TUBG1,PC,BAG2,PCNA,RUVBL2,MSH6,PRPS1,CTNND1,PSMD12,SRPRB,VDAC1,CSE1L,HUWE1,RANBP1,YTHDF2,KIF1C,RAD23B,RNF181,APEH,NEFL,RPN1,RAN,VDAC2,POLR2B,UMPS,BUB3,MCM4,GMPS,CUL3,CTSD,ILK,PSMD14,ATG3,SNX11,UGDH,TNFSF10,MARS1,PDHB,CNP,CCL3,PCK2,ARCN1,RARS1,ACAA2,ADSS2,PLAA,JUP |
| 8.367e-04 | -7.09 | ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog) | protein interactions | 51575 | 143 | 58 | 19454 | 5460 |
SEPTIN7,RPS24,RPL31,RUSF1,SNIP1,NSDHL,KRAS,LBH,H2AJ,RPS11,TMEM14B,CBX3,CDK8,ADAMTS1,ARL4D,NOP58,CSNK2A1,NGDN,IFI16,CALR,KPNA1,UQCR11,ANKRD50,DDX23,CHCHD1,MPHOSPH10,NUP50,RPA3,RPL27,PEBP1,BAP1,SIRT7,COIL,AATF,PSENEN,STAU1,EHHADH,MFAP1,ACACA,GRM2,CSNK2B,FGFBP1,EZH1,ZNF330,EIF4A3,SH3BGRL,ESR2,TCEAL7,IFI6,SPCS1,H2BC9,ANAPC15,FBXO7,MYC,PEA15,RIT1,UBE2H,MECP2 |
| 8.378e-04 | -7.08 | CLK3 (CDC like kinase 3) | protein interactions | 1198 | 212 | 81 | 19454 | 5460 |
MCM3,KPNA6,ATG101,CFAP20,HNRNPC,MYC,USP13,CASC3,PPIG,HSP90AA1,HOXC4,ELAVL2,RC3H2,YWHAZ,CHTOP,PRMT5,LRRC1,STUB1,ESR2,VIRMA,SRPK2,TNPO3,APEX1,CDC42,ZC3H14,DDIT4L,PABPC5,HEXIM1,LARP4B,SDCBP,MRPS34,NKAPD1,SAP18,TRA2B,APOBEC3F,TRA2A,SUV39H1,YWHAH,YWHAG,MRPS35,SPATS2L,MOV10,YWHAB,KPNA1,ZNF473,SNRNP70,EED,SRSF1,AIP,HSP90AB1,MRPS23,SRSF10,CDK9,PRNP,LYAR,PAIP1,PAIP2B,LBR,APOBEC3D,TP53,ZNF263,RNF8,PLD3,TOPORS,SRSF7,SRSF8,MRPS18B,ZC3H11A,PABPC1,ARGLU1,SNIP1,POLDIP3,AHCYL1,MEPCE,SRSF4,RPS27A,SRSF12,KPNA2,NUP42,THRAP3,CHCHD2 |
| 8.383e-04 | -7.08 | regulation of DNA biosynthetic process | biological process | GO:2000278 | 120 | 52 | 18204 | 5365 |
STN1,HNRNPA1,TP53,RFC3,PARM1,TNF,ADIPOQ,DKC1,NEK7,TOM1L1,PCNA,RFC5,CTNNB1,MYC,HNRNPD,WRAP53,SRC,HTR2A,RFC2,PTGES3,GREM1,CCT7,HNRNPA2B1,CCT8,JADE1,DNAJC2,HSP90AA1,KLF4,ING5,MEAF6,CDKN1A,RFC4,PKIB,TNKS,MAPKAPK5,SMG5,CCT2,NPPC,HNRNPC,HSP90AB1,CYP1B1,RGCC,PRKCQ,DCP2,RGN,NEK2,TNKS2,XRCC5,CCNA2,CCT5,NIBAN2,TCP1 |
| 8.435e-04 | -7.08 | TECPR2 (tectonin beta-propeller repeat containing 2) | protein interactions | 9895 | 16 | 11 | 19454 | 5460 |
RIGI,VPS16,GABARAP,VIRMA,VPS18,HNRNPL,CCR2,VPS33A,RAB5A,HSPA8,NUDCD3 |
| 8.435e-04 | -7.08 | FBXO16 (F-box protein 16) | protein interactions | 157574 | 16 | 11 | 19454 | 5460 |
NXT1,CETN3,SKP1,CETN2,TRIM54,HNRNPL,EDC3,CTNNB1,RSPH1,CSK,MORF4L1 |
| 8.435e-04 | -7.08 | NLRC5 (NLR family CARD domain containing 5) | protein interactions | 84166 | 16 | 11 | 19454 | 5460 |
SQSTM1,HSPA8,TOLLIP,HNRNPL,RIGI,VIRMA,IFIH1,CUL2,TOP3B,IKBKB,BRD3 |
| 8.435e-04 | -7.08 | IL12A (interleukin 12A) | protein interactions | 3592 | 16 | 11 | 19454 | 5460 |
FSTL1,S100A6,ACTA2,BCKDK,CXCL8,PIK3CG,F11R,RAB3B,CD28,IL12A,IL12B |
| 8.442e-04 | -7.08 | AP1S1 (adaptor related protein complex 1 subunit sigma 1) | protein interactions | 1174 | 58 | 28 | 19454 | 5460 |
TRMT61A,SPPL3,HNRNPL,STAT1,ARMC6,SEC61A1,AP2M1,AP1G2,COMT,XPO1,CAP2,ATG9A,MOV10,AP1M1,RIGI,FTL,PICK1,SLC16A1,RHOU,MRFAP1L1,RPA3,AP1S2,RPA2,PRDX3,FTH1,EBLN2,EEF1E1,E2F4 |
| 8.442e-04 | -7.08 | CACHD1 (cache domain containing 1) | protein interactions | 57685 | 58 | 28 | 19454 | 5460 |
RHOJ,ARF6,VIRMA,DYRK1A,CAV1,DIRAS3,EGLN3,LMBR1L,HRAS,RAB35,TMEM74,GJA1,RHOB,FBXW11,LAMTOR1,RAB11A,GGH,SCGB1D1,ST8SIA4,KRAS,RANBP10,STX7,TMT1A,PEBP1,RAB5A,IGF1R,RAB4A,CCL3 |
| 8.443e-04 | -7.08 | negative regulation of establishment of protein localization | biological process | GO:1904950 | 134 | 57 | 18204 | 5365 |
IL12A,DERL2,INPP5K,IL1B,CDK5,ANGPT1,DPH3,KCNJ11,PPP3CA,UBE2G2,OPRM1,PKIA,CD200,ADTRP,DRD3,PTPN11,CHP1,UBAC2,WWP2,NDUFAF2,IL12B,RAB23,SVIP,UCP2,ACVR1C,ADIPOQ,ENY2,KCNB1,GNAO1,ERLEC1,JAGN1,CCN3,ERP29,CSK,RSAD2,SFRP1,TXN,NEO1,MIR148A,SNX3,NDFIP1,SUFU,PKIG,LMAN1,GNAZ,SNX12,GHRL,UFM1,HADH,MIR146A,SYT4,OS9,SUMO1,LYPLA1,FKBP1B,CHGA,CD36 |
| 8.452e-04 | -7.08 | negative regulation of chemokine production | biological process | GO:0032682 | 31 | 18 | 18204 | 5365 |
EPHA2,MIR106A,MUL1,IL10,MIR214,MIR17,SOCS5,MIR26B,MIR34A,MIR140,OAS1,LILRB4,MIR146A,ARG2,KLF4,GSTP1,MIR590,IL6 |
| 8.452e-04 | -7.08 | negative regulation of amyloid precursor protein catabolic process | biological process | GO:1902992 | 31 | 18 | 18204 | 5365 |
PRNP,ROCK1,NTRK2,MIR29A,MIR361,MIR107,MIR153-1,CHRNA7,MIR186,IGF1,CLU,SPON1,MIR29C,RTN4,MIR339,MIR24-1,MIR455,MIR298 |
| 8.474e-04 | -7.07 | SLC30A1 (solute carrier family 30 member 1) | protein interactions | 7779 | 111 | 47 | 19454 | 5460 |
RHOG,LAMP2,RAB5C,XPO1,LAMP3,ARF6,MARCHF4,RHOH,STX6,DIRAS3,LMAN1,CAV1,RAB35,HRAS,SRSF1,ARL10,GJA1,RAC2,ARL4D,XXYLT1,RAF1,EPHA4,KRAS,RAB3B,FLOT1,CD83,LAMTOR1,LGALS8,RHOB,CSGALNACT1,RAB2A,CUL3,CSGALNACT2,DNAJC5,LGALS3,RHOJ,CLRN2,LMNA,ARL15,CDC42,RND2,SLC31A1,STX7,TNFSF12,RHOU,RAB9A,RAB5A |
| 8.474e-04 | -7.07 | FLAD1 (flavin adenine dinucleotide synthetase 1) | protein interactions | 80308 | 111 | 47 | 19454 | 5460 |
PTPN1,DNM2,PLEKHO2,GATD3,MOV10,SMAD4,RHOG,RB1CC1,MRPS26,HSPD1,HINT2,COX8A,SMN1,IMMP2L,SOX2,TULP3,PDHA1,CRABP2,SH3GLB1,APTX,CCNF,CLVS2,APEX1,AUH,CUL3,PMPCA,TUFM,NIF3L1,BICD2,TRIM23,SORD,UBE2H,FOXD3,RPA3,DUSP9,GFM1,HSCB,DUSP14,UBA52,ST7,CDKN1A,SDCBP,PTP4A2,SCGB1C1,CCL18,MTRES1,ANXA7 |
| 8.477e-04 | -7.07 | MSH6 (mutS homolog 6) | protein interactions | 2956 | 255 | 95 | 19454 | 5460 |
ACTR1A,H2AX,TP53,PPP4C,RAD1,FBXO25,RIGI,PTGES3,H3C1,KPNA2,HDAC6,CSNK2A1,H2AC14,USP15,TOPBP1,SNRNP70,DCK,H2AZ1,HRAS,ZBTB2,CDC5L,FZR1,TOP1,GABRA1,BRINP1,AKR7A2,CCND1,RPA2,DCTN4,RNF113A,RPA3,BAP1,NBN,SIRT7,DGCR8,FBXW7,NUCKS1,MORF4L1,DTL,ZBTB38,UBE2H,IVNS1ABP,GANAB,PTEN,PTPMT1,MACROH2A1,CCNF,ZNF330,VIRMA,FAF2,TNPO2,FEN1,ZNF263,ARFGEF1,SUPT5H,RNF126,MOB3C,HDAC11,PCNA,SSRP1,RAD21,G3BP1,PRDX1,IFI16,FAM174A,POU5F1,HSPB1,DICER1,DDX23,AGR2,BRD9,SRSF1,EGLN3,CEP19,SUMO2,MAP2K1,HSPA8,EP300,RFC4,XRCC5,COIL,SAMHD1,CASP4,MYC,CREBBP,CDKN3,CUL3,RUSC2,KIAA1191,MCM8,BRCA1,PARP2,MATR3,PRDX2,TRIM29 |
| 8.493e-04 | -7.07 | GTF3C3 (general transcription factor IIIC subunit 3) | protein interactions | 9330 | 206 | 79 | 19454 | 5460 |
FBXW7,EEF1G,HSCB,UFL1,COIL,TRIM52,SIRT7,PML,RPA3,BAP1,EP300,SQSTM1,RPA2,SDC2,FOXS1,HECTD1,AP5M1,SYK,CDK7,POLR1D,GTF3C4,CPT2,VIRMA,MAD2L2,ESR2,ZNF330,CIB2,CCNF,CPSF1,LMBR1L,PTEN,MACROH2A1,FGFBP1,ZMYM2,POLR3B,TXNIP,RIT1,UBE2H,DEDD,CUL3,SUB1,MYC,PCBD1,CPSF2,H3C1,NEDD8,KRAS,HUWE1,PAX6,SRSF4,PNMA2,EZH2,CDK8,TP53,RPL15,RPAP2,AURKAIP1,TOP1,MRPL50,RPS16,FZR1,CEP19,STX6,EGLN3,COQ8A,H2AZ1,EED,H2AC4,SNRNP70,BRD3,POU5F1,HNRNPD,ZCCHC10,IFI16,UBXN6,NT5C2,DDRGK1,CSNK2A1,XPO1 |
| 8.521e-04 | -7.07 | mitochondrial translation | biological process | GO:0032543 | 109 | 48 | 18204 | 5365 |
MRPS25,MRPL9,MRPS17,MRPS18B,MRPL10,MRPL12,MRPS9,MRPL24,MRPL13,MRPL52,MRPL49,MTRF1,MRPL22,MRPL36,MRPS21,MRPS23,MRPL57,MRPL41,MRPS33,MTG1,MRPL18,MRPL50,QRSL1,MRPL33,TUFM,MRPL20,MRPL47,MRPS16,AURKAIP1,MRPS35,MRPS7,MRPS34,MRPS18A,MRPS11,MRPL11,MRPL34,MRPL51,MRPL17,MRPL16,CHCHD1,MRPS26,MRPL40,MRPS28,MRPL23,GFM1,GFM2,MRPL53,MRPS18C |
| 8.549e-04 | -7.06 | malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | malignant_peripheral_nerve_sheath_tumour | 39 | 21 | 16828 | 4835 |
SS18,NFE2L2,EWSR1,KLF4,HRAS,KRAS,IDH1,TERT,PIK3CA,FGFR1,EZH2,CDH11,PTEN,TP53,KIT,MET,RB1,CTNNB1,ETV6,JAK2,AKT1 |
| 8.584e-04 | -7.06 | EIF3C (eukaryotic translation initiation factor 3 subunit C) | protein interactions | 8663 | 252 | 94 | 19454 | 5460 |
ENY2,USP3,CD81,CSNK2A1,MAP4,CD4,RPS16,PLEKHF2,RBM42,TP53,DDX39A,DNAJC2,SRP72,NUPR1,MAP1B,SNIP1,SEM1,EIF4EBP2,MEPCE,EIF3E,MED22,HMOX2,USP14,EIF3G,UBE2H,PSPC1,CCNF,METAP2,CSNK2B,RPS20,VIRMA,ATG16L1,EIF3J,RPA2,METTL14,EIF2B3,HSP90B1,HEXIM1,SNAPC1,RPA3,PPM1G,PML,EIF5B,EIF4E,IFI16,MRPS35,WWP2,XPO1,EIF3D,SMAD9,DRG1,RPL8,OCRL,RPL7,ACTN4,EZH2,SMNDC1,RPS11,GPBP1L1,EIF1AX,SART3,ALKBH4,UBE3A,RPS24,G3BP1,KRAS,UBE2A,PFDN1,PSMD12,RPS4X,RAD21,MYC,SFN,CUL3,PSMD1,BTF3,ICAM1,RIT1,EIF3K,SEC61B,PSMD4,EIF4A2,MATR3,BTG3,RPL10,EMC9,EIF4B,PIH1D1,HDAC5,RAB5A,AKAP1,EP300,STAU1,G3BP2 |
| 8.594e-04 | -7.06 | positive regulation of non-canonical NF-kappaB signal transduction | biological process | GO:1901224 | 66 | 32 | 18204 | 5365 |
ACTN4,RBCK1,TLR3,NMI,RC3H2,TRIM44,CALR,IL12B,TCIM,TNF,TLR7,PTP4A3,CD86,RPS3,PHB1,PDCD4,IL23A,NLRP3,EIF2AK2,TLR2,IL1B,MIR182,TLR9,IL18,TRIM26,PYCARD,AGER,TLR4,GREM1,IFI35,PHB2,CCL19 |
| 8.605e-04 | -7.06 | positive regulation of establishment of protein localization | biological process | GO:1904951 | 324 | 122 | 18204 | 5365 |
HSP90AA1,HUWE1,TOMM70,PRNP,LEP,LRRC8A,SNAP25,PARD6A,VEGFC,TLR4,TM9SF4,CDK5R1,RAC2,PDCD5,AKT2,DMAP1,WRAP53,CDK1,PPID,SRC,OAZ3,EFCAB7,HPCA,UBE2D3,OAZ1,MIEF1,IL13,PTP4A3,CDC42,PPIA,ACSL4,PGRMC1,DYNLL1,KCNB1,MDM2,TMEM30A,IFNG,TOMM7,SFN,CCT5,PPARG,TCP1,CD81,PSEN1,CAMK1,ATP2C1,STOM,PIK3R2,HDAC3,PIK3R1,RAN,HTRA2,PCK2,PLCB1,RBM22,JUP,BAP1,ACHE,MAVS,SAR1B,UBL5,OAZ2,PRR5L,FBXW7,PFKFB2,CCT7,HRAS,CCT8,TGFB3,CDK5,GOLPH3L,IL1B,VPS28,CTDSPL2,RHOU,RAB29,HYAL2,TCAF2,UBE2L3,PDCD10,TNF,APBB3,DKC1,EP300,IGF1,OSBP,SMAD3,IL1A,CHP1,TGFB2,F2,EDEM2,FIS1,TMEM97,ARF6,C2CD2L,GHRL,CFTR,CD38,CD2AP,ANP32B,NLGN2,TLR2,BAG3,GSK3A,CHRM3,PRKCB,PRKCE,GNA11,SRI,BAD,TSG101,JAK2,HCLS1,EDEM1,CHRM1,VAMP2,CCT2,OR51E2,NR1H2,SH3GLB1,SYBU |
| 8.606e-04 | -7.06 | regulation of pattern recognition receptor signaling pathway | biological process | GO:0062207 | 171 | 70 | 18204 | 5365 |
S100A8,USP15,TLR6,NFKBIL1,TLR4,HCFC2,SQSTM1,SEC14L1,MIR140,PELI1,FLOT1,PTPN22,ABHD17A,HMGB1,HSPA8,AKT1,NOP53,SRC,RSAD2,TRIM32,TNFAIP3,LGR4,BIRC2,PYDC2,NEK7,SARM1,LRRC14,IRF4,SLC15A2,LILRA2,MIR149,IFI35,MIR146A,NINJ1,BANF1,CSNK1A1,BPIFB1,MIR20A,RTN4,GFI1,MIR17,TLR9,ZNRF1,PIK3R1,UFD1,TICAM2,EIF2AK2,CD14,IRF1,MYD88,TRIM3,CD36,TAX1BP1,LYPLAL1,CGAS,ATAT1,RNF115,NLRP6,IRF7,TRIM11,CPTP,CAV1,MIR200C,TLR1,TASL,MIR708,TIRAP,TRIM15,MAVS,TAB1 |
| 8.623e-04 | -7.06 | APC/C:Cdc20 mediated degradation of Cyclin B | REACTOME pathways | R-HSA-174048 | 23 | 15 | 10285 | 3229 |
ANAPC16,ANAPC4,CCNB1,UBE2D1,CDC16,CDC23,ANAPC15,CDC20,CDK1,ANAPC2,RPS27A,CDC26,UBA52,ANAPC11,UBB |
| 8.623e-04 | -7.06 | Thromboxane signalling through TP receptor | REACTOME pathways | R-HSA-428930 | 23 | 15 | 10285 | 3229 |
GNG2,GNG12,GNB3,GNGT2,GNG3,GNA11,GNB1,GNG13,GNG10,GNG7,GNA14,GNB4,GNG5,GNAQ,GNG11 |
| 8.708e-04 | -7.05 | MCM3AP (minichromosome maintenance complex component 3 associated protein) | protein interactions | 8888 | 114 | 48 | 19454 | 5460 |
CETN3,SMAD3,NUP35,FAM118B,XPO1,UBXN6,ENY2,IFI16,SMAD9,EMC2,HAPSTR1,NUDT5,RIGI,RPL28,TRIM37,SEM1,DDX39A,ANAPC13,MGARP,TAF1D,TOP3B,RAF1,CYB5B,POLR2G,REP15,PELO,CCNF,VIRMA,TUBB,MCM3,CUL3,MYC,CRMP1,COP1,CDC73,LMNB1,NUP50,RNF113A,EP300,SIRT7,TIMP3,RPA3,AATF,CDC42,SEC22B,IER2,RPA2,LMNA |
| 8.708e-04 | -7.05 | CLN3 (CLN3 lysosomal/endosomal transmembrane protein, battenin) | protein interactions | 1201 | 114 | 48 | 19454 | 5460 |
ARF4,FKBP8,CSE1L,TMEM33,SLC25A5,B3GALT2,SLC25A10,SFXN1,SLC25A11,RPN1,TFRC,ERLIN2,CCDC47,B3GALT4,TOP3B,TMPO,ILVBL,OPRL1,CAND1,XPO5,HACD3,PHB1,ATG7,XPO1,ATP5MG,SEC61A2,UNC45A,GRPR,FADS2,CYC1,SLC25A3,SIGMAR1,SAMM50,TPRA1,TECR,KCNIP3,ARMC6,SLC25A4,SEC61A1,GANAB,UQCRC2,VDAC2,ATP1A1,XPOT,CALU,SYP,SLC25A1,DBH |
| 8.711e-04 | -7.05 | MACROH2A2 (macroH2A.2 histone) | protein interactions | 55506 | 191 | 74 | 19454 | 5460 |
SRPK2,CBX5,RPF1,RPL7L1,MACROH2A1,TRIM24,RPL37A,PARP2,ZNF189,DLST,ZNF22,CCNF,NSA2,CDKN2AIP,LMNB1,MCM4,RPL26,RPL7A,MYC,RPF2,BRIX1,FTL,NUCKS1,GPM6A,FBXW7,RPL4,HMGB1,MRPL34,NKAPD1,NLE1,PML,RPA3,PPM1G,ZNF770,HEXIM1,RPLP0,RPL26L1,ZCCHC17,WWP1,H2BC11,RPA2,ZBTB2,DKC1,TOP1,CGAS,HNRNPL,RPLP2,EED,MRTO4,H2AZ1,RPL8,BRD3,MED27,RIOX2,IFI16,HMGA1,SSRP1,RPS13,VRK1,HMGN4,TRIM26,H3C1,RUVBL2,RPL3,SNIP1,NUPR1,NECAP1,RBM34,H2BC1,CHMP4C,LLPH,RPL15,MAK16,TRMT1L |
| 8.711e-04 | -7.05 | SON (SON DNA and RNA binding protein) | protein interactions | 6651 | 191 | 74 | 19454 | 5460 |
YWHAG,PRPF19,IFI16,ZCCHC10,RBM17,MAGOH,YWHAB,BRD3,CHCHD1,SNRNP70,EED,HP1BP3,SRSF1,PHB1,CDC5L,ZBTB2,RPS16,BUD31,TOP1,RAF1,ILF2,HBP1,SMARCB1,EZH2,HDAC11,SEPTIN7,SRSF7,DHX9,SNIP1,SRSF4,UBE2A,SSRP1,TFPI,TRIM26,FBXO7,SNRPB,AR,NONO,PPP1CC,MYC,NDUFAF2,CUL3,PEA15,RIT1,UBE2H,FBXW11,CHCHD4,RC3H2,PTEN,SEC61B,PSPC1,SF3B6,CCNF,RAN,EIF4A3,VIRMA,ESR2,SRPK2,SNRNP40,ADRM1,SF3A1,USP39,RPA2,GRM2,HSPA8,SF3B1,EP300,NUP50,SNRPA,RPA3,NLE1,SIRT7,SAP18,STAU1 |
| 8.716e-04 | -7.05 | CCR chemokine receptor binding | molecular function | GO:0048020 | 50 | 26 | 18094 | 5411 |
CCL18,CCL24,CCR2,CCL3,DEFB114,MSMP,XCL1,CCL20,CX3CL1,CCL4L1,CCL2,CCL21,STAT1,CCL27,CCL8,CCL11,CXCL13,JAK1,CCL25,CCL23,CNIH4,DEFB1,CCL19,CCL1,CCL5,CCL17 |
| 8.732e-04 | -7.04 | GTF3C2 (general transcription factor IIIC subunit 2) | protein interactions | 2976 | 161 | 64 | 19454 | 5460 |
PAEP,PAX6,IMMP2L,RPL28,GTF3C3,H3C1,CHCHD2,BAG2,RPL3,RAD1,VAC14,PNMA2,EZH2,RPL15,SMAD1,TULP3,TP53,PNMA5,TRMT61A,EGLN3,STX6,TOP1,SUMO2,RB1,SDC4,USP15,BRD3,POU5F1,AHSA1,RPS2,DNAJC7,SNRNP70,DDRGK1,ZCCHC10,UBXN6,IFI16,DDX50,RPL4,FBXW7,EP300,RNF113A,GRIA2,RPA3,RPLP0,RPA2,FOXS1,SDC2,GTF3C4,RPL27A,ESR2,RPL10,PTEN,FGFBP1,ZMYM2,CCNF,LSM14B,UBE2H,SMAD2,ZBTB38,RBM27,PSKH1,MCM4,SUB1,MYC |
| 8.732e-04 | -7.04 | GRB10 (growth factor receptor bound protein 10) | protein interactions | 2887 | 161 | 64 | 19454 | 5460 |
GHR,SART3,NRN1,EXOSC3,H1-3,PPP2R1A,RAF1,TOP3B,RIGI,KIT,TRIM63,PICK1,NTRK2,BAG2,SRSF7,IGF1R,AKAP8L,HSPB1,PPP3CA,SKIC8,CRTAP,YWHAH,YWHAG,XPO1,CTNNB1,MAP3K14,PIK3R1,ELK1,HNRNPL,TOP1,RPLP1,AIFM1,WDR6,ALDH1A3,TFB1M,JUP,MAP2K1,IL2RG,UBA52,ZDHHC17,GRPEL1,G3BP2,HSPA5,HSPA8,EXOSC1,KCNA3,CDC73,RCL1,CHCHD4,FTSJ3,NOA1,YWHAZ,H1-10,BTF3,ZMYND19,AKT1,CCNB1,SFN,GRB10,UBB,AANAT,JAK2,SRC,CTNNA1 |
| 8.732e-04 | -7.04 | NOP14 (NOP14 nucleolar protein) | protein interactions | 8602 | 161 | 64 | 19454 | 5460 |
ZBTB2,CDC5L,SURF6,RPS16,FZR1,PHB1,KRR1,SNRNP70,CHCHD1,DDX23,ZMYND11,DDRGK1,RPL6,HMGA1,MOV10,IFI16,RIGI,RPS13,RPS24,RPL23A,RPL31,SNIP1,STX8,S100B,STX12,RPS11,EZH2,DCAF8L2,CBX3,CTLA4,BUD23,ESR2,VIRMA,APEX1,SNRNP40,FGFBP1,CSNK2B,ZNF330,EIF4A3,CPSF1,UBE2H,H1-1,LMNB1,TXNIP,HNRNPC,RAB11A,MYC,AATF,COIL,STX7,HMGB1,STAU1,EEF1G,UFL1,EP300,EMG1,NLE1,SIRT7,RPA3,HEXIM1,PPARG,RPA2,FOXS1,RPS14 |
| 8.741e-04 | -7.04 | CRYAA (crystallin alpha A) | protein interactions | 1409 | 188 | 73 | 19454 | 5460 |
ZDHHC16,TASL,PAFAH1B1,ATG16L1,WDR83,SYK,ADNP,JKAMP,ZMYM6,SDCBP,CRYAB,TMEM254,HSPB2,RAB29,CRYZ,WDR55,KDM1A,NAPG,TSR3,GORASP2,CCDC85B,BAG3,NTAQ1,CEP85,AKT3,CRYBB2,BAX,CRYBA1,RAB3C,TRIM24,ALB,ZMYM2,VAMP3,GNAI2,PSMB6,UBB,MED17,RNASEH1,STARD7,ZMYM4,SPG21,CER1,CSTF2T,ETFB,ARFGAP1,CRYGD,SESN2,OTULIN,PHC1,DISC1,CD209,STX8,NAT9,GTF3C3,CDC40,RBBP7,EDC3,CNOT8,SSBP4,SLC25A26,MPHOSPH6,HSPB1,BCL2L1,SLC20A1,DCAF11,DUS4L,SLC25A28,DCK,TRAPPC3,HCLS1,HMG20A,NUF2,PRELID1 |
| 8.754e-04 | -7.04 | KBTBD6 (kelch repeat and BTB domain containing 6) | protein interactions | 89890 | 94 | 41 | 19454 | 5460 |
HTRA2,FOSL2,MRPL18,TXNIP,TIAM1,MRPS25,LMNB1,COPS5,TAX1BP3,LMO2,INO80E,CUL3,TMPO,RPL10,MEAF6,DCUN1D1,RPL13A,AP2M1,TRMT10B,SRP14,DOK4,SURF2,UBE2M,ZNF574,FOXS1,LMNA,APOBEC3C,NFKBIL1,NUDCD3,MAP1LC3B,GABARAPL1,GABARAPL2,TULP3,IMMP2L,GABARAP,NEDD8,GREM2,FGF12,RPL31,TFPT,NOG |
| 8.759e-04 | -7.04 | BCAR1 (BCAR1 scaffold protein, Cas family member) | protein interactions | 9564 | 547 | 187 | 19454 | 5460 |
GNB3,MAGED2,YBEY,HNRNPL,TTC9C,ECHDC1,SUMO3,EEIG1,YWHAH,YWHAG,CTNNB1,UTP6,NCK1,CBL,SMAD9,YWHAB,SSNA1,FKBP2,TOMM6,TRMT1L,UBL5,FBXL7,PIR,CRKL,FAIM,TRMT11,DYNLRB2,TRIM29,FBXO22,ALG5,APEX1,SFN,BTF3,RPS6KA4,S100A11,PSMD14,FAM50B,P4HA2,ITGAV,SHMT1,QTRT2,PALS2,PAK2,MMP14,GAMT,NUFIP2,PIH1D1,COQ8A,GLT8D1,RAP1B,LCMT1,KCTD3,SELENOI,USP2,ZNF24,TSEN34,PSMG2,H2AC4,TMEM50B,TRAFD1,RPIA,MEPCE,SEPHS1,STRBP,MVD,TNRC6C,ESS2,H2AX,CHAMP1,NEFL,NECAP1,PSPC1,GCFC2,MID1IP1,MAP3K3,SRC,RNASET2,SUGP1,PTPN11,TIA1,CRLF3,RAP2C,TEX264,POLD2,MEA1,AIF1L,RBM22,STK38,HSPA5,CD2AP,CDC42,HPS6,FGFR1,TFB1M,MYEF2,TSG101,INA,MPP1,NUF2,STK3,NPC2,NUP35,TAF7,PIK3R1,LIPT2,MRPL18,FXYD6,ZYX,GNL1,FLOT1,SAR1B,OTUD6B,EZH2,SKA3,GNB1L,RAN,AP1G2,IFT172,MRPL23,SPCS1,NDUFB7,NFYA,TMED4,CFAP20,RIOK2,SLPI,YWHAZ,UPF3B,SNX24,TOR1AIP2,STXBP1,ARMCX3,PCLAF,LARP4B,RLIG1,PTPN1,SSU72,EIF4E2,EIF2B5,MDM2,SLC25A12,MRPL24,NOP9,MOV10,GOLPH3L,ASIC2,GARRE1,GNG5,PAK1IP1,CDK2AP2,MRPL22,GALNT2,IRGQ,PPIF,APOBEC3H,GNG10,GINS4,CASK,NUDT16,CCNF,GXYLT1,QNG1,GSK3A,GTF2A1,PTEN,TMOD3,MAGOHB,CD47,YES1,AAMDC,RPL26,SDF2L1,FXN,INPPL1,KIN,SLC7A1,CPSF4,PCK2,KCNH1,SLC35E1,CDK7,JUP,CHMP1A,PDCL,EPHX1,TTI2,PITPNA |
| 8.761e-04 | -7.04 | MED14 (mediator complex subunit 14) | protein interactions | 9282 | 164 | 65 | 19454 | 5460 |
ATP5MK,PGK1,NR1I3,MED13L,MED11,FBXW7,ACTL6A,GTF2H4,MED30,FBXL19,ELP3,COX6C,MED23,PPARG,USE1,HECTD1,MED31,POLR2F,STAT2,MED17,POLR2B,ESR2,VIRMA,LMO2,MED22,PSMD1,AR,MED10,RBBP8,STN1,ATG3,CDC73,RIT1,EMC2,MRPS11,KRAS,H3C1,CTNNBL1,PTGES3,VDR,TOP3B,SUPT5H,MED9,RPAP2,SMAD1,GINS4,CDK8,POLR2D,POLR2G,POLR2C,BIRC5,GTF2B,POLR2L,EED,BRD9,ATXN10,POLR2I,ASNSD1,ZCCHC10,ACTL6B,MED21,MED27,MED29,MED4,HNRNPD |
| 8.783e-04 | -7.04 | CCDC6 (coiled-coil domain containing 6) | protein interactions | 8030 | 167 | 66 | 19454 | 5460 |
MSN,UBE2I,SNRPD2,GSK3A,PSMA6,CREB1,CCNF,VIRMA,PSMB6,ADRM1,TMOD3,PPP1CC,CCNB1,ZNF250,CSK,RIT1,DNAJB6,YWHAZ,CHCHD4,PSMA3,STK26,EP300,SNAPC1,BAP1,SKP1,HSPA5,FBXW7,PAAF1,CD2AP,PSMB3,LPXN,FBXO42,ATG16L1,SF3A1,CNDP2,TFIP11,CDK1,PPP2CB,WIF1,EGLN3,CYTH4,TPM3,EXOC1,GAS8,EDC3,CSNK2A1,XPO1,YWHAG,YWHAH,PSMD3,YWHAB,MAP4,USP15,PCNA,PSME1,TFPT,PAX6,PSMA5,KRAS,PSMA2,HNRNPF,PPP2R1A,CCT5,MAX,MOB3C,PPP4C |
| 8.783e-04 | -7.04 | TP73 (tumor protein p73) | protein interactions | 7161 | 167 | 66 | 19454 | 5460 |
PRKACB,DSN1,TRIM32,MLF1,MYC,CREBBP,CCNB1,PRMT6,IGF2BP1,SMAD2,SP1,OAZ1,BAX,DNAJB6,BRCA1,TRMT11,UBE2I,STUB1,MAD2L1,CDC20,APEX1,PLAGL1,AGO1,CDKN1A,CCNA2,RPS14,CCND1,SUMO1,NFYB,BORCS8,CDK1,WWP1,IER2,EP300,AKAP1,PML,PIAS1,KDM1A,HMGB1,HSPB8,CSNK2A1,XPO1,GAS8,TPM3,WWP2,PFDN5,TOPBP1,NQO1,IKBKB,MUL1,DDX23,RB1,SMAD3,HRAS,RCHY1,MDM2,SOX2,JUN,ASPM,TP53,RTCB,SPSB1,ATF3,PAX6,PIWIL1,ASF1A |
| 8.783e-04 | -7.04 | H2AC8 (H2A clustered histone 8) | protein interactions | 3012 | 167 | 66 | 19454 | 5460 |
NOP16,MCM4,RPL26,PRKACB,MRPL16,RPS17,ZCRB1,ANAPC4,PARP2,LIG3,DLST,PELP1,RPS3,MACROH2A1,VIRMA,ELK4,MRPL10,H2BC11,APOBEC3C,MACROH2A2,RPL26L1,HIRA,PPM1G,SOD1,CCDC86,H2BC12,CFDP1,HMCES,PRKCB,MRPL57,RPS15,MRPL17,KDM1A,GINS3,SPATS2L,DDX50,MOV10,COPS5,MPHOSPH10,PPM1B,EID1,MRPL18,CDC23,HNRNPD,KRR1,H2AZ1,HYPK,RPS10,CAND1,RPS16,POLR3F,CETN2,SURF6,PDHA1,GINS4,EZH2,RPL31,HSD17B10,RPS24,RPL3,VDAC1,HUWE1,H1-6,NEDD8,SSRP1,MCM6 |
| 8.783e-04 | -7.04 | CIP2A (cellular inhibitor of PP2A) | protein interactions | 57650 | 167 | 66 | 19454 | 5460 |
SEMA4C,G3BP1,PSMA1,LAMB2,CCAR1,CD83,EFNB1,POC1B,ABCE1,SIGLECL1,CA14,CYB5B,IL1R2,TNRC6C,KBTBD4,COMTD1,PPP2R1A,ACTR1A,PRNP,CNTROB,EGLN3,LRRC61,LMAN1,RBM5,ST6GAL1,SYNCRIP,CD274,SLC25A28,FXYD6,TOPBP1,MED4,TSPAN10,LRRC4,NDC80,PIK3R1,DDRGK1,XPO1,P2RY10,NPTN,KDM1A,BAP1,CXCR4,CD40,RPA3,PSMA3,STOM,RPA2,CDK1,FAM234A,CFTR,NPY2R,NEK2,HCST,TUBB,EFNA5,CHRM4,SCN2B,LMBR1L,STUB1,PHF21A,GSK3A,BRCA1,GPR17,RAB11A,CUL3,MYC |
| 8.784e-04 | -7.04 | EXOSC8 (exosome component 8) | protein interactions | 11340 | 182 | 71 | 19454 | 5460 |
EXOSC8,TOP3B,TP53,ILF2,DDX42,EZH2,EXOSC3,RPL3,TCEA2,MDC1,POLDIP3,LSM4,KRAS,DNAAF10,DDRGK1,DIS3L,MOV10,IFI16,COX5A,USP2,MED4,DNAJC4,MPHOSPH6,PRR3,EIF4E2,TMPO,SRSF10,MORN4,LMO4,DDIT4L,SYK,SNRPN,KCNJ11,TFIP11,RPLP0,PALS2,MED23,RPA2,METTL14,P4HA2,EXOSC4,C1D,SNRPA,BAP1,MACIR,RPA3,TXNDC17,RPS28,RPP14,METTL22,UFL1,RASD1,RBM22,STAU1,PRPF31,RFC5,NTAQ1,SNRPB,CRMP1,EXOSC1,RBM7,UBE2H,FYTTD1,BRCA1,HAPLN2,PHF21A,CCSER2,EIF2AK2,ESR2,SRPK2,RBBP4 |
| 8.795e-04 | -7.04 | azurophil granule membrane | cellular component | GO:0035577 | 59 | 29 | 19108 | 5553 |
TMEM30A,GLIPR1,RAB37,LAMTOR1,BST2,RAB3D,TOM1,TMEM179B,PSEN1,SYNGR1,SURF4,RAB5C,NDUFC2,CMTM6,BRI3,LAMP2,VAMP8,PRCP,SNAP29,VAMP1,RAP1B,VAMP7,ATP8A1,CD63,NCSTN,B4GALT1,STOM,DNAJC5,CPNE1 |
| 8.796e-04 | -7.04 | BCAS2 (BCAS2 pre-mRNA processing factor) | protein interactions | 10286 | 246 | 92 | 19454 | 5460 |
CWC15,CDC5L,PLEKHF2,FZR1,TOP1,SPMIP5,BRD3,MED29,SNRNP70,CSNK2A1,CTNNBL1,TSSC4,CDC40,ERLEC1,SNIP1,PPP4C,DISC1,EMILIN3,ESS2,TRAF1,FGFBP1,ZMAT5,SF3B6,EIF4A3,GCFC2,UBE2H,RC3H2,TADA3,IFI35,HMGB1,FBXW7,OIP5,RBM22,CWF19L1,INPPL1,RPA3,TFIP11,RPA2,SPMIP6,WDR83,SF3A1,SNRPN,SRSF10,PGR,RPS10,BUD31,EED,PRCC,MAGOH,DDX23,DDRGK1,LAMP2,IFI16,PRPF19,PSMD3,WWP2,PFDN5,SSRP1,ENKD1,TFPI,KRAS,BAG2,SNRPE,HGS,MOB3C,SOX2,NCSTN,RAF1,ESR2,SNRPB2,SNRNP40,SF3B4,SNRPD1,FHIT,LMNB1,SNRPB,LMO2,DSN1,MYC,TXNRD2,UFL1,HNRNPA0,MYOZ3,KRT222,SF3B1,HSPA8,EP300,SNRPA,PPARG,KRTAP8-1,LMO4,LMO3 |
| 8.797e-04 | -7.04 | NOP16 (NOP16 nucleolar protein) | protein interactions | 51491 | 179 | 70 | 19454 | 5460 |
RPL35,RPL7L1,SRPK2,RPL19,RPL10,EIF2AK2,PRKRA,FGFBP1,RPS9,MECP2,ATG3,RC3H2,H1-1,RIT1,MYC,RAB11A,CIAO1,RPL7A,RPL26,ZNF668,DGCR8,NPM3,STAU1,FBXW7,RPL4,MRPS7,THUMPD1,RAB9A,RNF113A,RPLP0,BET1,KLF12,SPPL3,RPS10,CAND1,LYAR,CGAS,RBM42,STK3,KLF9,NAP1L5,KRR1,SRSF1,PHB1,HP1BP3,MRPL18,DRG1,LHX2,IFI16,WWP2,COPS5,DDRGK1,KRAS,SRSF4,MEPCE,RPL17,RPL31,RPL23A,SOS2,RPL3,EZH2,SRP72,CERK,RAF1,RPSA,NCSTN,APOBEC3D,AURKAIP1,SOX2,H1-3 |
| 8.797e-04 | -7.04 | RAB10 (RAB10, member RAS oncogene family) | protein interactions | 10890 | 170 | 67 | 19454 | 5460 |
HEXIM1,RPA2,DUSP22,HSPA5,STAU1,FLCN,HSPA8,RAB33B,RTN4,PMAIP1,BAP1,RPA3,NRP1,CDC73,ZMPSTE24,UBE2H,LAMTOR1,SPOP,DCAF4,RHOB,CFL1,TOMM40,BTF3,AR,USP14,OST4,MTG2,MYC,RAB11A,CUL3,SMURF1,UBE2L3,RABIF,VIRMA,ESR2,TAGLN2,MOB4,UQCRC2,LMBR1L,OPTN,MOB3C,FURIN,EZH2,GDI2,SOX2,RAF1,UBL4A,E2F4,FKBP2,TRIM37,EMC2,HSPD1,AGR2,HDAC6,LAMP3,DDRGK1,LAMP2,DPP4,ADIPOR2,RAB5C,PPIA,ZBTB2,HNRNPL,RAB1B,HRAS,COQ8A,FUBP3 |
| 8.804e-04 | -7.04 | NOC4L (nucleolar complex associated 4 homolog) | protein interactions | 79050 | 173 | 68 | 19454 | 5460 |
UFL1,NPTN,STAU1,STX7,AATF,RPA3,LCA5,SIRT7,EMG1,LMNA,RPA2,PRSS23,ZNF574,ZBTB42,RPS14,TANK,RPL35,RPGRIP1L,RPL19,ESR2,FGFBP1,RC3H2,ATG3,UBE2H,RIT1,H1-1,MYC,CUL3,DNAJC8,H1-6,KRAS,TOLLIP,RPL17,STX8,RPL31,S100B,PLSCR1,BHLHE40,PICK1,RPL23A,CTLA4,DISC1,STX12,RPS11,SART3,RAF1,SOX2,DDX39A,RPL29,RPS7,NOP58,ARL6IP5,RPS16,FZR1,RPL7,DKC1,EGLN3,SURF6,CDC5L,KRR1,FBXO32,PRR3,SNRNP70,CHCHD1,IFI16,RPL6,DDRGK1,NT5C2 |
| 8.804e-04 | -7.04 | ALDH18A1 (aldehyde dehydrogenase 18 family member A1) | protein interactions | 5832 | 173 | 68 | 19454 | 5460 |
DNAJB6,UBE2H,COP1,STK11,NONO,CUL3,RALB,MYC,MAD2L2,VIRMA,DYRK1A,SMU1,CCNF,PIH1D1,HEXIM1,FKBP10,IDH2,RPA2,CDK7,CDC42,TIMM13,AGTRAP,PAFAH1B1,SF3A1,NT5C3A,GRPEL1,PIAS1,STAU1,FBXW7,ADRB2,UFL1,UCHL3,EP300,HSPA8,HDAC5,AMACR,SIRT7,RPA3,USP15,DDX1,SMCHD1,AGR2,TIAM1,EDC3,DDRGK1,MOV10,EGLN3,TES,FAHD1,ARHGAP25,ARL10,CERK,NUPR1,ILF2,CHMP4C,PDHA1,EZH2,PPP2R1A,TP53,RAF1,CBLL1,MEPCE,G3BP1,SOS2,TRIM21,ZC3H7A,HNRNPA2B1,HSPD1 |
| 8.804e-04 | -7.04 | PPP1R10 (protein phosphatase 1 regulatory subunit 10) | protein interactions | 5514 | 173 | 68 | 19454 | 5460 |
ESR2,VIRMA,PPP1R10,FBXO22,PTEN,SF3B4,CTTN,PSPC1,TACO1,CPSF1,RCL1,RIT1,UBE2H,MECP2,SNRPB,NONO,RBM15B,PPP1CC,ARHGAP21,MYC,AAMDC,G3BP2,STAU1,PML,SNRPA,RPA3,MFAP1,NUFIP2,HEXIM1,TOX4,MED23,RPA2,PPP1CB,CAPN1,CDK9,MDM2,PRNP,LSM5,TOP1,FZR1,FAM98A,WDR82,TIAM1,MPG,PPIL4,ZNF24,WWP2,SSRP1,MEPCE,TRIM37,HNRNPK,KCTD17,G3BP1,HUWE1,ERLEC1,RPL23A,FAM76B,SNIP1,FURIN,TAF2,DDX42,EZH2,ISG15,SUPT5H,TP53,RPSA,CSNK1E,RAF1 |
| 8.814e-04 | -7.03 | ficolin-1-rich granule | cellular component | GO:0101002 | 185 | 74 | 19108 | 5553 |
HSPA8,STBD1,PSMD3,PSMA2,CCT8,SERPINA1,CSNK2B,ILF2,FGL2,FCER1G,DYNLL1,PSMD12,PPIA,CD58,FCAR,PSMC3,HSP90AB1,IDH1,HSP90AA1,ATP6AP2,ACTR1B,COMMD9,ATG7,CAND1,GSTP1,PSMD6,HUWE1,MMP9,CSTB,SERPINB10,YPEL5,COTL1,EEF2,CST3,PGM1,NME2,CTSB,ACTR2,CAB39,SLC2A3,APEH,FTH1,PSMB1,CALML5,SIGLEC5,LILRA3,LAMP2,TBC1D10C,ENPP4,SERPINB6,PRCP,PRDX4,PGAM1,TMEM179B,PSMD7,LAMTOR1,MIF,LGALS3,PSMB7,TNFAIP6,JUP,CAPN1,EEF1A1,PSMA5,HMGB1,CTSD,PNP,HBB,PAFAH1B2,SRP14,COMMD3,PLEKHO2,PDAP1,PSMD14 |
| 8.820e-04 | -7.03 | RNA localization | biological process | GO:0006403 | 174 | 71 | 18204 | 5365 |
PIH1D1,UPF3B,NUP35,TOMM20,XPOT,IGF2BP1,CCT2,DDX39A,TNKS,NUP62,SMG5,MRPL18,XPO5,RBM15B,NUP50,TCP1,CASC3,NUP153,TGFBR2,TST,BICD2,RAN,ALYREF,GLE1,FXR2,CETN3,PRPF31,FYTTD1,ALKBH5,THOC1,EIF4E,SEC13,STAU1,NUP37,EIF4A3,RTRAF,CETN2,NCBP2,PHAX,DDX39B,MAGOHB,NOP58,NXT2,DKC1,MAGOH,G3BP2,PEG10,RFTN2,ENY2,THOC6,POLDIP3,XPO1,THOC2,NUP107,MX2,HNRNPA1,THOC3,FUBP3,FLOT1,HNRNPA2B1,NUP42,ZC3H11A,PARP11,SRSF7,ZNHIT6,ZNHIT3,SRSF1,NXT1,CHTOP,DHX9,WRAP53 |
| 8.844e-04 | -7.03 | KLHL13 (kelch like family member 13) | protein interactions | 90293 | 80 | 36 | 19454 | 5460 |
COPS2,HEXIM2,ETV6,FAM219B,FIBIN,VIRMA,MAD2L1,TRIM29,DCUN1D1,KLHL22,COPS5,MZB1,CUL3,KLHL9,COPS7A,IGFBP4,HSP90AA1,NXT2,UBE2D1,KLHL15,KLHL28,VIP,NOG,RPA3,TFG,PRPS1,COPS4,ZMYM4,SOX9,DDX39A,NUDCD3,UBE2M,HEXIM1,ZMYM6,ENC1,RPA2 |
| 8.844e-04 | -7.03 | PLGRKT (plasminogen receptor with a C-terminal lysine) | protein interactions | 55848 | 80 | 36 | 19454 | 5460 |
USP30,EEF1G,COX17,SAT1,CLPB,AKAP1,MAVS,RPA2,EZH2,ATP5PO,SAMM50,FAM136A,TOMM22,MTX2,TIMM13,TIMM8A,CHCHD3,TOMM70,PARL,PLGRKT,RMND1,TIMM8B,COX4I1,COX7A1,WDR45,SEC23A,CDCA3,CHCHD6,KIAA1191,AK2,HAX1,KARS1,PDIA3,COX6B1,COX5A,TOMM40 |
| 8.844e-04 | -7.03 | SFXN2 (sideroflexin 2) | protein interactions | 118980 | 80 | 36 | 19454 | 5460 |
TNFSF8,NPTN,DCP2,HSCB,NF2,RPA3,SFXN1,MGAT4B,PML,VIPR1,LRRN4CL,RPA2,GP9,ILF2,TMEM14B,SLC25A3,RBFOX2,MGARP,TOMM7,SNX2,AGK,REEP4,TOMM70,RAMP3,EGLN3,CCNF,SLC1A1,SPCS3,SLC2A1,SYP,PDZK1IP1,THTPA,UBE2H,MAPK4,CUL3,LAMP3 |
| 8.855e-04 | -7.03 | YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon) | protein interactions | 7531 | 1150 | 370 | 19454 | 5460 |
TMEM11,CDK12,CD274,CDR2L,ARL6IP5,CD28,TMPO,CDC5L,UBL4A,IPO8,H2AX,ARPC3,GRAP2,TAB2,RNF8,TBC1D4,FGF12,TNFAIP3,FAM110B,RC3H2,ATP1A1,RPS3,ZBTB33,KCTD9,PRKCE,ROCK1,TFEB,SRC,NMI,BCCIP,NDUFAB1,CFTR,RPA2,BORCS5,UBE2M,HEXIM1,HECTD1,CWF19L1,FAM53C,PRDX6,GSTM3,PPFIBP1,TBC1D5,NT5C2,STK4,AGR2,YWHAB,HSPB1,SRSF1,DYNC1I2,ERRFI1,CRTC2,SOX2,MSX2,HPCAL1,MTA2,ZRANB2,RBM3,RPAP3,RUVBL2,KRAS,VDAC1,LMO2,RUSC2,PAPOLA,BRMS1,BEX3,TFDP2,EFHD2,FAM83B,ATP5F1B,PAFAH1B1,ISCU,PAK2,KLC2,PIH1D1,LCA5,HDAC5,HSPA8,STK26,YAF2,CALR,EMC4,HDAC6,ARL2BP,ESYT1,TIAM1,SSX2IP,RCHY1,KCTD15,G6PD,TBK1,MAP1LC3B,LBR,DDX39A,ING1,UAP1,ILF2,CASK,CAMK2G,EIF3E,CSK,CAP2,DEPDC1B,ATP5F1A,NONO,LGALS8,IVNS1ABP,NCKIPSD,HYCC1,STUB1,EIF4A3,GSK3A,SH3BP4,ATG16L1,SIPA1L1,PAK5,JUP,LSM2,CDR2,RPLP0,SQSTM1,NPM3,PPP1R2,USP8,PFKFB2,RPL4,STOML2,SAV1,CHST11,RASSF8,CDKN1B,CAMSAP2,PHB1,RBIS,CCAR2,RAB11B,WDR37,EZH2,STIM1,NGB,GPBP1L1,ATP6V0B,JAK1,FHL3,GPSM3,UBE3A,G3BP1,TRIM26,SRSF4,GRB10,CUL3,TAFAZZIN,LMNB1,WDR20,TNFAIP8,RMDN3,SPINDOC,RBBP4,TMCC1,GNB1,RTKN,CRY1,IL1B,GPC1,PSMC1,WASF3,MTMR12,GAPDH,API5,EDC3,SHC1,TSNAX,SSBP1,FZR1,CAND1,LCP2,KIF1C,TP53,CBX3,DISC1,CAPN2,NUPR1,DHX9,H3C1,NEDD8,HNRNPK,MEPCE,RGL2,PSMB2,AKT1,TRIM32,KCNQ5,ARHGAP21,ARL6IP6,DTL,PDCD4,RBM7,UBE2H,CCSER2,PPP2R5E,MAP3K3,DAPK3,DYRK1A,CDC42,BAP1,PGK1,SNX33,GRPEL1,RPL6,WWP2,XPO1,YWHAG,YWHAH,SPATA2,DDRGK1,CTNNB1,QPCTL,SLC8A1,ARL14EP,CBL,GSTA1,HNRNPL,CDK17,HSP90AB1,MIEF1,HEXA,SNAPIN,TUBA1A,TUBB4B,MOB3C,SCPEP1,TRIM21,PSMA1,PTPN4,VAMP8,PAK6,PRPS1,MYC,LDHB,HNRNPC,SFN,ATG101,BTF3,TESPA1,BAG3,TBC1D1,CKB,FBXW11,H1-1,SESTD1,DLST,ADH1B,RRAS2,REEP3,MATR3,ACAP2,NCKAP1,ESR2,USP6NL,LMO3,PPT1,MAP2K1,EIF4B,CSNK1A1,MACIR,CNKSR3,JAKMIP1,SF3B1,TRA2B,SRSF2,UFL1,EEF1G,FAM53B,OSBPL8,EIF4E2,ACTA2,EFCAB7,DCUN1D1,MMP20,FAM13B,ACTR2,PPP1R12A,FAF1,GARRE1,CCNY,IGF1R,HUWE1,RNF115,PTGES3,RIGI,STK38L,IFNAR1,RACGAP1,CDC73,CCNF,GAB1,METAP2,STOX2,POLR3H,COPE,TMOD3,RHOJ,FERMT2,VIRMA,SYNRG,CDK7,FTH1,WTAP,AGAP1,SHOC2,DVL2,RPA3,SOD1,PRKCB,MIS12,PDHB,PIK3R2,FBXW7,PIK3R1,HMGA1,HNRNPA1,PPM1B,RB1CC1,PLEKHO2,USP46,KRT8,EGLN3,SRSF10,KIAA0232,STK3,CSNK1E,RAF1,ACTN4,CHMP4C,MTMR2,POLR2D,ZYX,HNRNPA2B1,PRPSAP1,SRSF7,TESK2,MSL2,SAR1B,ENKD1,PDE7A,PRPF31,MAP3K21,ARHGAP19,YWHAZ,BRCA1,PFDN4,HSP90AA1,PFDN2,BAD,SNRPD1,ACTB,TAB1,TENT5C,TUBB,REEP4,CLIC4,JAK2,PRRC2A,NDE1,INPP5E,SUPT4H1,VAPB,ISOC1,PAFAH1B2 |
| 8.892e-04 | -7.03 | mitochondrial respirasome | cellular component | GO:0005746 | 83 | 38 | 19108 | 5553 |
UQCC3,NDUFB10,UQCR11,NDUFV2,UQCRQ,CYC1,COX4I2,NDUFB4,NDUFC2,COX6C,NDUFA1,COX8A,NDUFB5,NDUFA12,COX4I1,NDUFA5,COX7B,NDUFB8,BCS1L,COX6A2,NDUFB6,UQCRC2,NDUFS3,SDHB,COX7A1,COX6B1,UQCRC1,NDUFAB1,SDHC,COX7B2,COX5A,NDUFB7,NDUFS8,NDUFS2,NDUFA2,NDUFA4,UQCRH,NDUFS6 |
| 8.892e-04 | -7.03 | caveola | cellular component | GO:0005901 | 83 | 38 | 19108 | 5553 |
NOS1AP,BMPR2,CDH13,KCNMA1,FLOT1,CAV2,CAV1,IGF1R,SLC2A1,ADTRP,RANGRF,TGFBR2,SMPD2,HTR2A,SLC6A3,EMP2,CORO1C,HDAC6,CAV3,FASLG,ADRA1A,BVES,CTNNB1,SLC22A6,CD36,CBL,SRC,MLC1,ATP1A2,LRP6,CAVIN2,EFNA5,BMPR1A,CTNNA1,SPRED1,TFPI,ATP2B4,JAK2 |
| 8.901e-04 | -7.02 | RBM10 (RNA binding motif protein 10) | protein interactions | 8241 | 243 | 91 | 19454 | 5460 |
SSRP1,CBLL1,CCAR1,TRIM37,ZNF526,DHX38,E2F4,RBM12,DHX15,MIR214,WDR82,PRCC,PHB1,MAGOH,AHSA1,DDX23,DDRGK1,HNRNPA1,WWP2,IFI16,PRPF19,UFL1,DDX5,ZFP64,SF3B1,PEBP1,SNRPA,MTF1,MIRLET7D,SNRNP40,SF3B4,RIT1,FBXW11,CUL3,MYC,MDC1,HNRNPK,HUWE1,EMC2,HAPSTR1,NUPR1,CASK,IK,THAP1,TP53,FBP1,CDC5L,MDM2,TOP1,MAPRE2,MIRLET7G,KLF1,SPPL3,FZR1,MCL1,MIR106B,SYNCRIP,ZNF473,SNRNP70,CSNK2A1,RBM17,MOV10,AATF,HSPA5,MIR107,FBXW7,HNRNPH2,MIRLET7I,RPA3,BAP1,MIR21,UBE2M,LMNA,RPA2,CDK7,SF3A1,ATG16L1,VIRMA,DYRK1A,SMURF1,EIF4A3,CCNF,RPS3,UBE2H,BAHD1,RBM7,RC3H2,TXNIP,AR,CEP70,SUGP1 |
| 8.909e-04 | -7.02 | organelle localization by membrane tethering | biological process | GO:0140056 | 74 | 35 | 18204 | 5365 |
STX16,ESYT1,SNAP25,STX11,SNAP29,STX8,STX17,EXOC8,VAMP3,EXOC5,BVES,PSEN2,STX1A,STX12,EXOC1,VAMP8,EXOC3,STX6,CFTR,GNAO1,YKT6,VTI1B,VMP1,AHCYL1,CPLX2,VPS18,STX10,CAV2,STX7,EXOC2,STX5,KCNB1,STXBP1,VAPB,PPFIA3 |
| 8.922e-04 | -7.02 | ROR2 (receptor tyrosine kinase like orphan receptor 2) | protein interactions | 4920 | 327 | 118 | 19454 | 5460 |
ZMYM4,DUSP1,DDX39A,TAB2,SFTPC,SOX14,BHLHE40,DUSP19,DUSP21,CD1B,LAMP3,MOV10,ESYT1,TES,RAC2,SEC23A,CDCA3,SRPRA,ELSPBP1,HRAS,PTPN1,CAV1,STX6,ARF6,KLRD1,CDC42,TMEM106A,DUSP18,ATG16L1,LEMD3,PICALM,CDK1,RAB9A,RHOU,TMEM209,HSPA5,YKT6,GORASP2,DNAJC5,PTPN11,CCNB1,SLC25A1,RAB2A,DNAJC10,SDF2L1,SEC61A1,SMAP2,DUSP10,RHOJ,COPE,MSX2,DNAJC25,GTPBP1,MTMR2,RND3,RPN1,STIM1,NUDT19,FHL3,MYO1B,SLC39A7,TMT1A,NDUFA4,FLOT1,PFDN1,KRAS,DDRGK1,YWHAG,YWHAH,ISX,PIK3R1,LAMP2,ATG9A,YWHAB,NCK1,PPM1B,RHOG,CDK5RAP3,GJA1,DUSP6,TNIK,WDR6,RAB35,WDR44,DIRAS3,RHOH,ASIC1,OCRL,HNRNPL,SEC62,OTULINL,RND2,NOTCH2,DUSP14,MTMR6,USP6NL,ARCN1,OGFOD3,VAPB,RAB5A,FAM168B,ACTMAP,STX7,EMC1,CYFIP2,RAB11A,SFN,PIK3R3,NIBAN2,HSP90AA1,SCFD1,YWHAZ,RHOB,LAMTOR1,B4GAT1,NCKAP1,TAB1,MB21D2 |
| 8.930e-04 | -7.02 | RNA polymerase complex | cellular component | GO:0030880 | 105 | 46 | 19108 | 5553 |
POLR1D,ERCC3,TAF2,GTF2A2,GTF2F2,GTF2H5,CCNH,MCM3,POLA2,TENT2,SUPT3H,GTF2A1,TAF10,POLR2F,POLR3B,TAF5L,TAF11,POLR3GL,ENY2,GTF2B,TAF9,POLR2D,MNAT1,POLR3F,POLR2I,POLR1B,TAF7,POLR2G,POLR3H,POLR2C,POLR2B,TCEA1,CDK7,POLR2L,GTF2E2,GTF2F1,TADA3,PAAF1,GTF2H2,GTF2E1,SKIC8,CDC73,TERT,GTF2H4,POLR1H,PRIM2 |
| 8.943e-04 | -7.02 | dedifferentiated | COSMIC cancer mutations | dedifferentiated | 27 | 16 | 16828 | 4835 |
FBXW7,IDH2,TP53,CTNNB1,KIT,RB1,PTEN,NAB2,PIK3CA,TERT,IDH1,KRAS,HRAS,EWSR1,SS18,NUP107 |
| 8.944e-04 | -7.02 | NABP2 (nucleic acid binding protein 2) | protein interactions | 79035 | 69 | 32 | 19454 | 5460 |
SOD2,LUC7L3,TBC1D4,PPP2R1A,EEF1A1,PPIF,YIPF5,COMTD1,INTS6L,SUPT5H,TP53,NDUFA2,SKP1,SSRP1,G3BP1,SRPRB,KLHL15,EP300,NBN,VPS4A,SERPINH1,PSMD7,BRCA1,MYC,SUGP1,CUL3,POLR2B,ESR2,PSMD6,MRPL53,SSBP1,PRCC |
| 8.944e-04 | -7.02 | RAB8B (RAB8B, member RAS oncogene family) | protein interactions | 51762 | 69 | 32 | 19454 | 5460 |
NEDD8,RADX,RAB13,HSPA8,HSD17B10,RAB5A,AKAP1,JUP,RPA2,IK,GDI2,HEXIM1,CNDP2,UBL4A,RAP1A,TUBA1A,CNPY3,RAB1B,ARF6,RALA,ACTB,TUBB,RABIF,RAP1B,TES,PSMB1,TUBG1,RHOB,C9orf72,RAB2A,RAB5C,CTNNB1 |
| 8.957e-04 | -7.02 | KIF21B (kinesin family member 21B) | protein interactions | 23046 | 45 | 23 | 19454 | 5460 |
VIRMA,TMEM248,POLE3,FBXO22,LDLR,FUBP3,CPSF1,SYNCRIP,YWHAB,PFDN6,MED4,CAPG,YWHAH,NTAQ1,YWHAG,HSPA5,TICAM1,TRIM3,NUPR1,HAUS2,P3H1,TUBB4B,UBL4A |
| 8.957e-04 | -7.02 | PRKD3 (protein kinase D3) | protein interactions | 23683 | 45 | 23 | 19454 | 5460 |
RHOB,MED29,LAMTOR1,RAN,PELP1,GSK3A,STAT1,VIRMA,TP53,RAF1,NUDT3,SKA2,VAMP2,ATP5PO,UBE2M,SH3GLB2,NDUFA4,SNX33,DLAT,HDAC5,POLL,KPNA2,BCL6 |
| 8.977e-04 | -7.02 | side of membrane | cellular component | GO:0098552 | 715 | 246 | 19108 | 5553 |
TNFRSF9,KLRD1,CXCL12,S100A6,OMG,GNAZ,F2,LEPR,AP2S1,TAS2R16,BTN2A2,FCGR2A,CFC1,GNGT2,CCR7,THBD,CD40,SNX18,AP2A1,TRAF1,CD209,PRND,GNAI3,CD3G,CXCR4,GNG2,LYNX1,FASLG,IL2RA,CD1D,FOLR2,FAS,LY6G6C,CD1E,PRNP,CD83,CD1B,CTSB,CALR,CLEC6A,OTULINL,RGMB,KRAS,EEF1A1,TFPI,GNA14,ALCAM,CYTH1,FOLR1,PKP4,EFCAB7,ALPL,GNG3,SLAMF9,BORCS6,JUP,PALM2AKAP2,CD59,FCGR2B,THY1,KXD1,CCR5,GNB1,MICB,HM13,SPPL3,FCER1G,AP2M1,PCSK9,GNG7,ADAM21,RGMA,MOG,IL12B,HSPA8,GPC4,FCGR1A,FERMT2,SNAPIN,CXCL10,CD80,HTRA2,RACGAP1,CDIP1,GNAO1,F10,SPRN,SERPINA5,TMEM123,ATP6AP2,JAK1,C2CD2L,IL6ST,CD200R1,FLOT1,KIT,RPS28,ENPEP,GNAI2,CD40LG,GNA11,ITGA6,MYD88,GNG10,JAK2,BIRC2,ASTN1,CD1A,TNFRSF14,GNG11,SLC38A1,GNB3,CCR3,CD28,CD248,CHRNB2,GPIHBP1,CTSA,LRRC24,RAB5A,CD86,GHR,CXCL9,B4GALT1,CD52,GRIA2,HYAL2,ACKR3,EFNA5,BMPR1A,DNAJC19,BORCS5,KCNJ3,FCN2,BECN1,PTEN,GPC1,SEMA7A,NTNG2,BORCS7,TIRAP,PDCD1,CD79B,CD2,MIEN1,NEGR1,GNAQ,LY6H,CEACAM5,ABCG2,TAPBP,IGSF21,CD9,PTPN22,CCR4,PPP3CA,SOCS3,GNG12,CAPN2,LYPD6,CLEC12B,RS1,CNTN1,CD34,LITAF,AQP4,CD226,CACNB4,BST2,GNB4,LY6G5C,KLRC2,MBL2,DLG4,DAG1,CTSK,TGFBR2,IZUMO1R,IKBKB,IDE,ITGA2,CCR1,CD14,AZGP1,TRAF3IP2,NRN1,TLR8,RPL27,FKBP1A,SELL,PDCD1LG2,DLG1,AQP2,TFRC,CHMP4C,LILRB1,EFNA3,PTPN4,CXCR3,GLRA1,GNG5,CD36,CXCR6,RPS29,KCNAB1,BORCS8,RPS26,DPEP3,HFE,ITGAV,GNG13,TRAF2,G6PD,LILRB4,BLOC1S2,ABCB1,SNX5,CLEC2B,CD4,RGS1,CDH13,CX3CR1,PTPN1,NOA1,B2M,CNTN2,ICAM1,LDLR,PLG,ACHE,CD274,IL13,IL2RG,RGS2,CTLA4,CNTFR,TLR4,CCR6,TRAF6,CCR2,CXCR1,DPEP1,CD1C,IL2RB,TNF,STAC3 |
| 9.041e-04 | -7.01 | positive regulation of cold-induced thermogenesis | biological process | GO:0120162 | 101 | 45 | 18204 | 5365 |
HADH,FABP4,IRF4,CCR2,IL4,BSCL2,GHRL,HDAC3,GJA1,ADRB3,DIO2,G0S2,VEGFA,CD36,ALPL,KDM1A,FABP5,ELOVL6,CAV1,JAK2,ACHE,LEP,ADIPOR1,GRB10,ADRB2,ADRB1,STAT6,CXCR4,PLAC8,IL18,TSHR,SYK,GADD45G,ADIPOR2,OXTR,IL13,CPT2,PRKAB1,LEPR,IGF1R,DBH,HCRT,UCP2,ADIPOQ,ELOVL3 |
| 9.073e-04 | -7.00 | UBIQUITIN_1 | prosite domains | PS00299 | 10 | 8 | 12186 | 3388 |
FAU,USP14,UBL4A,UBA52,NEDD8,UBFD1,UBB,RPS27A |
| 9.081e-04 | -7.00 | CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2) | protein interactions | 830 | 403 | 142 | 19454 | 5460 |
CDKL2,VMP1,ZMPSTE24,MYO6,DCAF4,LAMTOR1,BTF3,PDE4B,PKP4,MYC,ESR2,PSMB6,ACTB,GPNMB,TRIM29,SSH3,PSMD4,BST2,AP2M1,DLST,CNOT6,EIF4B,RBM18,DET1,TIMM13,PPP1CB,DUSP14,EFHD1,UNC45A,PACSIN3,LYG2,STAP1,DCTN3,HADHA,STK26,NMRAL1,HSPA8,SPECC1L,DDX39B,STAMBPL1,CBL,CTNNB1,CNOT8,WWP2,CNOT2,EGLN3,AASDHPPT,KCTD10,SPTAN1,KRT8,PLEKHO2,CORO1C,PDHA1,SMNDC1,EZH2,ACTN4,CCS,CSNK1E,LYPLA1,RAF1,FLOT1,G3BP1,ACTR1B,MYO1B,ATF3,MAPRE1,UBE2H,AP2A1,NCKIPSD,RC3H2,AR,PPP1CC,USP14,RACGAP1,CFL1,MTPN,ARHGAP21,CFL2,GNAI2,VIRMA,SH3BGRL,RPGRIP1L,DAPK3,DAPK1,TMOD3,RPS20,SGTA,PSMC5,CALML5,CTTN,CCNF,CDIPT,WTAP,TMOD1,DYRK2,IDH2,PICALM,COX6C,RPA2,DCTN4,CDK7,CFTR,CRAT,NEK2,CD2AP,FAM161A,ATG16L1,SPTBN1,PDHB,TNFAIP1,ARPC2,SQSTM1,RNF113A,HSPB2,DCTN6,BAP1,LIN7C,RPA3,TPM3,HDAC6,PLEKHO1,MYL12A,CDK9,FCHO2,PRNP,FZR1,PPP1R18,ADD1,NUPR1,ARPC3,ACTR2,H2AX,ACTR1A,FBP1,CAPZA1,LPCAT3,CNOT6L,CNOT7,CAMK2G,PPP1R12A,RAB1A,PALM2AKAP2 |
| 9.106e-04 | -7.00 | CLU (clusterin) | protein interactions | 1191 | 237 | 89 | 19454 | 5460 |
DYRK1A,SRPK2,VIRMA,ARMC6,TUFM,DNAJC5,RSPH1,SYVN1,PML,CLU,HSPA5,KDM1A,TTR,LEP,LEPR,METTL14,FGFR1,HSP90B1,COQ8A,EXTL2,TMPO,MDM2,PRNP,HP,FAM20C,MICB,NFKB1,DPP4,IGF1R,MAN1A2,GARRE1,ZNF451,PCYOX1L,DDR1,MDC1,EDEM2,TF,TGFBR2,TOLLIP,GPAM,H2AX,MSRB1,SERPINA1,FURIN,IL20RB,DISC1,CD209,HSPA13,DLG4,NFKBIA,VEGFA,BTG3,ESR2,NLGN2,BAX,HSP90AA1,NTRK3,ATG3,RBBP8,EP300,VLDLR,TMEM106B,FOS,CCND3,GPC1,RPE,GINM1,MAP1LC3A,TNIK,LILRB4,CYP4F8,TENM3,XPO1,PDIA3,BCL2L1,HSPB1,RPL23,LYZ,HAX1,HBA1,UBE3A,MMP9,HSPD1,RAD21,CCAR1,TNF,SOX2,SERPINA3,CHMP4C |
| 9.116e-04 | -7.00 | CHCH | prosite domains | PS51808 | 23 | 14 | 12186 | 3388 |
COA5,COX19,COX6B2,CMC4,NDUFB7,COX6B1,COX17,CHCHD2,CHCHD1,CMC1,CHCHD6,COA4,CHCHD3,CHCHD4 |
| 9.124e-04 | -7.00 | CLPTM1L (CLPTM1 like) | protein interactions | 81037 | 97 | 42 | 19454 | 5460 |
CUL3,CALU,PEX3,RNF139,LMNB1,TUBG1,SEC61B,SYNGR1,DNASE1L1,ZBTB33,CCNF,VIRMA,ESR2,UQCRQ,SPTAN1,MARCHF4,NCSTN,CDC42,OTULINL,MRPL47,E2F4,CCDC47,NDE1,KCNF1,PDHA1,SFTPC,AQP3,RPN1,RPA2,VAPB,AKAP1,VIPR1,TMEM106B,EXD2,NCDN,RPA3,COIL,ADRB2,DNAJC30,CD1B,STAU1,HSCB |
| 9.129e-04 | -7.00 | HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1 like 2) | protein interactions | 144983 | 120 | 50 | 19454 | 5460 |
TMEM33,HNRNPF,HNRNPDL,MEPCE,UBE2A,NKRF,HNRNPA2B1,RAB1A,CYP2C9,HSD17B10,STX18,GUCD1,PDHA1,EXOC3,TFCP2,MRPL49,PI15,SUMO2,FZR1,MRPS23,CYGB,HNRNPD,IFI16,HNRNPA1,HNRNPA0,HSPA5,HTR1A,PNO1,CFDP1,HNRNPH2,CRY1,PPT1,LMNA,TOX4,HEXIM1,HNRNPH3,WDR77,DUSP14,MTF1,MATR3,SRC,UBE2V2,UQCRQ,TMA7,DLST,TRIB1,SERPINH1,HNRNPC,CATIP,MYC |
| 9.129e-04 | -7.00 | ANKRD13A (ankyrin repeat domain 13A) | protein interactions | 88455 | 120 | 50 | 19454 | 5460 |
WBP2,TRIM10,CXCR4,RNF11,TSPAN5,RP2,DIO3,CFTR,CSNK1G3,STOM,TCP11L1,CTDSP1,EDNRA,SCAMP2,LMBR1L,LRRC3B,SMAD5,SMURF1,UBTD1,PSMD4,RALA,CSK,MLF1,TNFAIP3,RALB,RHOB,DESI2,TSPAN17,LDLRAD4,SLC2A8,RIGI,RPS27A,PDRG1,FBXO25,TOLLIP,CTDSP2,STMN2,TMEM31,ZNRF1,IZUMO1,DCK,CAV1,CYSTM1,PRNP,KCNMB2,CCR6,XPO1,PGAP3,ASB7,KCNIP2 |
| 9.131e-04 | -7.00 | mitochondrial proton-transporting ATP synthase complex | cellular component | GO:0005753 | 20 | 13 | 19108 | 5553 |
ATP5F1B,ATP5PO,ATP5MK,ATP5F1D,ATP5PB,ATP5PD,ATP5F1E,PPIF,ATP5MC3,ATP5MC1,ATP5MG,ATP5F1A,ATP5PF |
| 9.135e-04 | -7.00 | DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5) | protein interactions | 80331 | 365 | 130 | 19454 | 5460 |
ITM2B,LIN7C,CLU,PIK3R2,FTSJ1,YKT6,NF2,CFTR,TPT1,ARHGAP1,PIP5K1A,SEC22B,SPTBN1,CSNK1G3,MET,SLC12A2,GOLGA5,JUP,CTDSP1,SGTA,SRP54,CTNNA1,NECTIN2,STUB1,VAMP3,GAB1,FERMT2,TECR,SH3BP4,YES1,ST13,DEPDC1B,EXOC5,HSPA14,SNX5,OAT,EPHA2,SLC6A1,AP2A1,ATP1B3,SYP,SNAP23,TTPAL,SLC16A1,ATP2B4,DLG1,FKBP8,ADD2,SLC6A8,CTNND1,TMEM33,REXO2,SNAP29,CASK,NECAP1,TFRC,SURF4,EXOC3,CDCA3,SLC39A10,ADD1,CAV1,CD2,STX6,SLC38A2,LMAN1,SNAP91,RELL1,OSBPL8,DNAJC7,NOS1AP,TIAM1,SLC2A1,PMAIP1,SLC32A1,STX7,ZDHHC17,VAMP1,NOTCH2,DAAM1,USP6NL,NUFIP2,FKBP10,FAM83B,SLC30A7,CHCHD3,GRM8,BAG3,RAB11A,PKP4,TXNRD2,PIK3R3,NIBAN2,MYO6,LAMTOR1,FAS,BAG2,EFNB1,AHCYL1,PSMD12,VAMP8,PPP2R1A,SNAPIN,TMEM59,KHDC4,TPD52,MARCKSL1,AP2S1,HGS,PLD3,CYB5B,PTGFR,STX12,VAMP2,NEO1,GJA1,WDR6,PTK7,TMEM237,VAMP7,SNX2,SPTAN1,CTNNB1,PPFIBP1,WWP2,PDIA3,YWHAB,SLC20A1,TRAF6,SCAMP5 |
| 9.181e-04 | -6.99 | V_SNARE | prosite domains | PS50892 | 12 | 9 | 12186 | 3388 |
VAMP1,YKT6,VAMP2,VAMP5,STXBP6,VAMP7,VAMP8,VAMP3,SEC22B |
| 9.186e-04 | -6.99 | regulation of glycoprotein metabolic process | biological process | GO:1903018 | 61 | 30 | 18204 | 5365 |
MIR106A,ITM2B,PXYLP1,RAB1B,MIR31,FKTN,PLCB1,AATF,MIR17,MIR20A,CCL21,HBEGF,ACOT8,MIR153-1,POMT2,MIR147A,CCR7,CCL19,MIR298,MIR455,MIR101-1,CHP1,MIR144,CST3,IGF1,IL15,ITM2A,CTNNB1,RAB1A,NCSTN |
| 9.206e-04 | -6.99 | CHEK1 (checkpoint kinase 1) | protein interactions | 1111 | 234 | 88 | 19454 | 5460 |
SFN,MCM3,SNRPB,MCM4,H1-10,YWHAZ,RHOB,BRCA1,RIT1,FHIT,HSP90AA1,BAD,VEGFA,MCPH1,TCEAL1,BTG3,DAAM1,CDKN1A,MAP2K1,RNF7,XRCC5,RAP2A,FEM1B,YWHAG,XPO1,YWHAH,CDK5RAP3,YWHAB,BCL2L1,HNRNPD,HAX1,TYMS,RPS10,E2F4,TUBA1A,NEK9,PCNA,KRAS,NAT9,RPS27A,MCM6,AKT1,RACGAP1,CDC73,DTL,FBLN5,CCNF,PTEN,CSNK2B,SRC,UBB,NEK2,FAXC,CNTN2,CDK1,MET,NBN,SNX11,TCEA1,PRKCB,FBXW7,DGCR8,AATF,USP3,XAF1,NFKB1,CSNK2A1,COPS5,HDAC6,SMAD4,TOPBP1,EIF4E2,RB1,TOP1,FZR1,KCTD3,CDC5L,CDK9,TP53,PIK3CA,RNF181,PPP1R12A,EIF1AD,IGF1R,CLPB,TOM1,MSH6,TUSC3 |
| 9.211e-04 | -6.99 | SRP-dependent cotranslational protein targeting to membrane | biological process | GO:0006614 | 22 | 14 | 18204 | 5365 |
SEC63,ZFAND2B,SRP14,SEC61A2,SSR3,TRAM2,TRAM1L1,SEC61B,SRPRA,TRAM1,SEC61A1,SRPRB,SRP54,SRP72 |
| 9.286e-04 | -6.98 | PFDN5 (prefoldin subunit 5) | protein interactions | 5204 | 296 | 108 | 19454 | 5460 |
TUBA1A,GFPT1,SPG21,TUBB4B,METTL21A,PDIA6,PREPL,CCT8,BCKDK,PFDN1,CPLX1,TFG,KRAS,PCGF3,RBBP7,DHRS4L1,PRPF19,EEIG1,DCAF11,PPP3CA,DCAF5,SKIC8,XPO5,WDR82,SIN3A,PPP2CB,PSMB4,PRPF18,CCT7,PGS1,DYNC1I2,TANK,TCF19,TRAPPC6A,GSTO2,NEUROG2,DUSP9,FBXW4,GPC1,TTC33,SNRPB,BRMS1,MTG2,MYC,CUL2,SP1,PFDN4,PFDN2,PFDN6,RIT1,FAM221A,CCT2,FBXW11,DCAF4,HAPLN2,DOK4,ELK3,SCNM1,GNB1,RPL10,SNRNP40,TUBB,ACTR1A,TBK1,DOK5,GUCD1,POC1B,PPP1R12A,BHLHE40,EGR1,PHF1,RIGI,DYNC1I1,RNF115,CALR,SMG9,MAP4,TUBG1,ELSPBP1,EEF1AKMT3,FZR1,CRAT,PSMC4,PAX9,CIMIP1,RPRD1B,SDCBP,SAMM50,ARPC2,GFM1,BAP1,FAM222B,PRPF4,BCL6,KDM1A,NME4,NTAQ1,YPEL5,CDC73,UHMK1,NIF3L1,ATOSB,RC3H2,TUBA1B,SMAP2,VIRMA,KCTD9,ARMC6 |
| 9.286e-04 | -6.98 | PTK2 (protein tyrosine kinase 2) | protein interactions | 5747 | 296 | 108 | 19454 | 5460 |
TCOF1,CCR5,SLC25A10,IGF1R,WASL,NEDD8,RIGI,VPS16,SOCS2,CDK4,TP53,FBP1,EXOSC8,SOCS3,DDX39A,RBM34,PIK3CA,HSPA13,CDK6,SURF6,MDM2,ILVBL,SPATS2L,GAPDH,DAG1,CSNK2A1,GNG2,SHC1,TUBG1,SMAD4,FGR,DVL2,MME,NF2,PIAS1,LPXN,WDR83,MND1,JUP,CTTN,STUB1,PTEN,CSNK2B,YES1,CD47,SRC,ROCK1,PTPN11,RPL7A,CSK,AKT1,KCNMA1,KCNB1,UBE2H,EPHA2,EXOSC1,PPAN,BAG2,CDK5,RPL28,TUBA1A,TRAF2,OTUD6B,NUDCD3,PTRH2,OTULIN,CRKL,GTPBP1,ITGB5,SWAP70,DNM2,NEO1,SH2D1A,TRIM15,HNRNPL,CACYBP,PIK3R1,CTNNB1,MMUT,YWHAG,NCK1,RB1CC1,CBL,CXCR4,RFC4,RAB5A,NUP50,STAU1,EEF1G,ITGAV,TGFB1I1,SHMT1,SYK,PPP1CB,MAP2K1,CD79B,DOK4,TRMT6,SNRPD1,RPL7L1,STAT1,GNB1,RPL10,JAK2,ESR2,PIK3R3,MYC,HSP90AA1 |
| 9.303e-04 | -6.98 | ependymoma_Grade_III-IV | COSMIC cancer mutations | ependymoma_Grade_III-IV | 18 | 12 | 16828 | 4835 |
HRAS,KRAS,IDH1,TERT,SMARCB1,PTEN,TP53,RB1,CTNNB1,IDH2,AKT1,NF2 |
| 9.303e-04 | -6.98 | endometrium-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-clear_cell_carcinoma | 18 | 12 | 16828 | 4835 |
PIK3CA,TERT,EP300,PTEN,TP53,KRAS,CTNNB1,HRAS,FBXW7,PPP2R1A,AKT1,PIK3R1 |
| 9.303e-04 | -6.98 | gliosarcoma | COSMIC cancer mutations | gliosarcoma | 18 | 12 | 16828 | 4835 |
CDKN2C,IDH2,CTNNB1,KIT,TP53,PTEN,PIK3CA,TERT,IDH1,KRAS,HRAS,SF3B1 |
| 9.316e-04 | -6.98 | MMAB (metabolism of cobalamin associated B) | protein interactions | 326625 | 123 | 51 | 19454 | 5460 |
DNAJC19,MTG2,TNFAIP3,AUH,PMPCA,TUFM,MYG1,PARL,TACO1,MTG1,CCDC90B,TRIM68,MTRES1,UBA52,UBLCP1,CD59,HSCB,CRYZ,NGRN,EXD2,GFM1,ZCCHC9,RHOG,TMEM70,MRPS26,MTRF1,GRSF1,DBT,RAB11B,SSBP1,GATD3,RP9,PDHA1,OXNAD1,GFM2,RBPJ,CDK5R1,MRPL11,HADH,DDX39A,AURKAIP1,METTL15,SERTAD1,RPIA,FASTKD5,IMMP2L,FAF1,HSPD1,SFXN1,HINT2,COX8A |
| 9.316e-04 | -6.98 | ACOT1 (acyl-CoA thioesterase 1) | protein interactions | 641371 | 123 | 51 | 19454 | 5460 |
COX14,PPIA,GATD3,COX4I1,SSBP1,AIFM1,TST,MRPS26,TMEM70,CHCHD1,RHOG,SLC35A5,GRSF1,MTRF1,IMMP2L,FASTKD5,HINT1,COX8A,HINT2,PCNA,SFXN1,HSPD1,GFM2,PDHA1,NUDT19,METTL15,AURKAIP1,MRPL11,RAF1,PARL,LGALS3,CCDC90B,TACO1,DNAJC19,CA2,TUFM,CFL1,PMPCA,AUH,MTG2,CRYZ,HSCB,SQSTM1,GFM1,EXD2,RPA3,NGRN,MTRES1,ACAA2,RPA2,CNP |
| 9.331e-04 | -6.98 | PCNA-Dependent Long Patch Base Excision Repair | REACTOME pathways | R-HSA-5651801 | 21 | 14 | 10285 | 3229 |
POLE4,RFC3,RPA3,RFC2,RFC5,POLD4,POLD2,RFC4,RPA2,FEN1,POLE3,APEX1,PCNA,POLB |
| 9.331e-04 | -6.98 | Presynaptic function of Kainate receptors | REACTOME pathways | R-HSA-500657 | 21 | 14 | 10285 | 3229 |
GNG10,GNG7,GNB4,GNGT2,GNB3,PLCB1,GNG11,GNG5,GNG2,GNG3,PLCB2,GNG13,GNG12,GNB1 |
| 9.336e-04 | -6.98 | Hexapeptide repeat proteins | gene3d domains | 2.160.10.10 | 8 | 7 | 14470 | 4137 |
EIF2B5,EIF2B3,DCTN6,GMPPA,GMPPB,UGP2,FPGT |
| 9.337e-04 | -6.98 | URM1 (ubiquitin related modifier 1) | protein interactions | 81605 | 30 | 17 | 19454 | 5460 |
ATP6V1A,CTU1,TXNL1,DSTN,GDPGP1,CEP41,PRDX2,KRAS,SPPL3,USP5,PTGES3,ACBD6,MOV10,PRDX1,DDX39A,TOMM40,XPO1 |
| 9.337e-04 | -6.98 | TDP1 (tyrosyl-DNA phosphodiesterase 1) | protein interactions | 55775 | 30 | 17 | 19454 | 5460 |
LIG3,PRMT5,POC1B,UCHL3,KPNA2,TOP1,SSRP1,MOV10,CSK,FEN1,NUP153,VAMP2,POLB,TDP1,CHTOP,RBPJ,APTX |
| 9.337e-04 | -6.98 | Hnrnpk (heterogeneous nuclear ribonucleoprotein K) | protein interactions | 15387 | 30 | 17 | 19454 | 5460 |
LPAR1,SRSF10,RBM42,RBM3,CCNF,SNRPA,PTEN,GANAB,SMU1,PRR3,ZCRB1,YWHAZ,APOBEC3C,RBM7,SMARCB1,RALYL,EXOSC8 |
| 9.337e-04 | -6.98 | PRUNE2 (prune homolog 2 with BCH domain) | protein interactions | 158471 | 30 | 17 | 19454 | 5460 |
EIF3K,RPS24,EWSR1,SNX2,DYNC1I2,YES1,SNX1,HNRNPL,SRC,VIRMA,PDE2A,RPSA,ATG9A,UBLCP1,MAP1LC3B,RPS5,RPS26 |
| 9.358e-04 | -6.97 | DNA-binding transcription factor binding | molecular function | GO:0140297 | 476 | 174 | 18094 | 5411 |
FOXP1,GTF2I,HAND2,HIRA,SOX9,TADA3,SMARCD3,CHCHD2,DDRGK1,PHB2,PRMT2,TCF21,HEY2,DHRS7B,TCF23,POU1F1,KLF4,WWP2,NFKBIA,PPID,E4F1,SMAD2,FBP1,ZNHIT3,DAPK3,HDAC11,MTA2,MED4,FOXP3,TAF9,CREBBP,CGGBP1,SMAD4,ANXA4,TP53,LMO2,NR0B1,PIAS1,MED17,LDB1,MYC,CTBP1,SDR16C5,EIF4E,ELK1,CDK5RAP3,TRIM24,HDAC3,TRIP4,NFYB,STAT1,DUSP26,RNF14,NR4A2,TRIM32,GTF2A2,CD34,HSPB1,VDR,YWHAZ,SMARCB1,SRC,TGFB1I1,SP1,CRTC2,NCAPG2,BCL10,PAGR1,NKX3-1,CBX5,RAD23B,SRI,TRIM6,SOST,RBBP8,MKKS,BUD31,NUCKS1,PADI2,ACTN4,FAF1,LMO4,TAF11,ACTB,IFI27,NBN,SRARP,LMO3,ZBTB17,PCNA,EP300,CALR,DDIT3,CSNK2B,DDX5,WBP2,COMMD6,HMGA1,CEBPG,DMAP1,PPARG,FOS,C1D,BCL6,SIN3A,NIF3L1,RAD21,NR1H2,KDM1A,TRIM68,CTNNB1,SETD3,MEF2C,DHX9,NR1I2,RPS3,GMNN,MAX,CRKL,TAF10,HMGB1,PSMC5,SMAD3,TTC8,HCLS1,EGR2,H2BC9,JUN,PSMA6,CXXC5,BHLHE40,LYAR,MED30,TLE1,ATF4,YWHAH,PPARA,STAT5A,SMARCE1,CREB1,TAF7,RBFOX2,PROX1,FKBP4,RERG,CPNE1,ID4,LRIF1,MTDH,NOTCH2,GTF2B,STK4,JUP,AR,ADD1,RBPJ,RB1,CNOT7,GTF2A1,NLRP3,THRAP3,CRY1,BBS5,TRIB1,AIP,MEF2A,MAD2L2,TOB2,GABARAPL1,HDAC5,PRKCB,BRMS1,NFE2L2,PSMD10 |
| 9.361e-04 | -6.97 | ACKR4 (atypical chemokine receptor 4) | protein interactions | 51554 | 14 | 10 | 19454 | 5460 |
CCL25,CCL2,SURF6,CCL8,CCL21,CCL19,HAPSTR1,CCL5,CCL11,CXCL13 |
| 9.361e-04 | -6.97 | CORO7-PAM16 (CORO7-PAM16 readthrough) | protein interactions | 100529144 | 14 | 10 | 19454 | 5460 |
RPA2,PDHA1,PXMP2,IMMP2L,RPA3,AIFM1,SEC62,OTULINL,COX8A,AKAP1 |
| 9.361e-04 | -6.97 | C16orf54 (chromosome 16 open reading frame 54) | protein interactions | 283897 | 14 | 10 | 19454 | 5460 |
ANKRD46,RPRM,DDR1,PIK3R3,PMP22,PKP4,EFNB1,LHFPL4,SEC22A,CLDN11 |
| 9.382e-04 | -6.97 | DNAJB14 (DnaJ heat shock protein family (Hsp40) member B14) | protein interactions | 79982 | 61 | 29 | 19454 | 5460 |
DNAJC7,FBXW11,PPIB,HDAC6,ST13,PDIA3,FAM20C,FAM174A,LMAN1,GANAB,SGTA,LMBR1L,UQCRC2,STUB1,SRP14,RPN1,PLS3,HSP90B1,CFTR,TMEM231,CCDC47,MARCKSL1,GRPEL1,TUSC2,RIGI,HSPA8,TTC1,BAG2,ERP29 |
| 9.382e-04 | -6.97 | TBCE (tubulin folding cofactor E) | protein interactions | 6905 | 61 | 29 | 19454 | 5460 |
ACACA,RNF7,TUBB4B,RPA2,DIRAS1,CENPM,ASF1A,KRAS,TRIM11,IGF1R,BAG2,HSPA8,TMEM263,RPA3,RIT1,CYP1A1,BICD2,MLF1,AKT1,APEX1,CEP19,ACTB,TUBB,IRF2BP1,ARF6,RPL35A,GNPDA1,FBXO32,NFKBIA |
| 9.395e-04 | -6.97 | acyltransferase activity | molecular function | GO:0016746 | 727 | 256 | 18094 | 5411 |
PAFAH1B2,MARCHF3,UBE3A,LRAT,RNF103,ATG3,ZDHHC17,AANAT,CERS2,RNF113A,RNF128,RNF144B,GTF3C4,FBXO7,ASB1,SPTSSA,PPP1R11,OSGEP,PRPF19,GNPAT,SAT2,UBE2K,TOPORS,FBXO3,UBE2I,RNF8,CUL3,UBE2S,TRIM62,TRIM11,GTF2B,UBE2G2,GLYAT,RNF40,MSL2,COP1,RNF7,RNF133,PML,TRIM15,TNFAIP1,HUWE1,UBE2B,DTL,ZDHHC15,RBCK1,SMARCE1,UBE2E3,ANAPC4,ABHD5,UBE2N,UBR7,JADE1,GNPNAT1,RNF148,UBE2M,SYVN1,G2E3,MED30,TRIM10,SIRT7,ZDHHC16,HERC4,RNF122,ELOVL6,TRAF3IP2,TLCD3B,NAA16,WWP1,EGR2,UBL4A,ZDHHC8,MED10,HMGCS1,RNF34,SIAH2,MEAF6,IFNB1,SAT1,GGT7,BRAP,RCHY1,ACAT1,TRIM22,TAF10,TNFAIP3,FBXO9,TRIM21,ABHD4,ZDHHC4,PLAAT3,OSGEPL1,AREL1,RMND5B,PRDX6,SMURF1,CDK8,TRIM54,RNF146,TRIM68,UBE2L3,NEURL2,RNF10,TRIM35,RLIM,CBLL1,MARCHF4,FBXO44,RNF41,NAA30,BRCA1,RNF11,CERS6,RNF167,RNF208,HADHA,BIRC2,CCAR1,NAA50,TRAF2,ZDHHC14,NAA15,UBE2W,NAT2,MAEA,NT5C2,RNF187,MYLIP,MED27,EP300,ZBED1,MED21,LNX2,NOSIP,GLYATL3,MCAT,UBE2D3,GPAM,RING1,ABHD14B,UBE2H,TRIM63,ELP3,HECTD3,TRIM23,RNF152,ELOVL3,TRAF6,TRIM6,CDC23,GLUL,QPCTL,RNF141,DBT,RNF20,MUL1,PLA2G15,LPCAT3,MARCHF9,BFAR,HECTD1,TRIM37,UBE2D1,DLAT,PIGW,TRIM44,YKT6,ZNRF1,MED31,GID4,TRIM8,CDC42,TRIM34,RNF39,HECW1,ATG16L1,SHPRH,TAFAZZIN,ATAT1,FBXO30,TRIM45,TRIM32,ANKIB1,NAA11,STUB1,RNF14,TRIM27,HERC3,PELI1,ACAA2,PLAAT5,IRF2BPL,PCGF3,PELI3,DLST,RNF181,PNPLA4,TRIM24,FBXO11,RNF182,FBXO22,IRF2BP1,UBA3,AGPAT1,NAA60,MDM2,CPT2,UBE2E2,TRAF7,PIAS1,ELOVL4,ZNF451,MED17,FBXL14,TRIM52,RNF5,CUL2,CREBBP,RNF139,TRIM3,RNF121,RNF26,UBE2F,TAF9,RNF126,WWP2,WSB1,SIAH1,MED11,MARCHF5,CRAT,ANAPC11,FBXL3,UFL1,TRIM5,FBXO25,CPT1B,WDSUB1,RC3H2,KCTD10,RNF115,KLHL9,RAG1,SPTSSB,ZDHHC24,TRIM26,VPS18,LIPT2,TRIM36,ELOVL1,CBL,NAT9,ELOVL7,PAFAH1B3,UBE2A,AGPAT5 |
| 9.453e-04 | -6.96 | ARHGEF19 (Rho guanine nucleotide exchange factor 19) | protein interactions | 128272 | 53 | 26 | 19454 | 5460 |
HP1BP3,FUBP3,CWC15,NUP35,INA,SMARCE1,MECP2,ZCCHC9,FYTTD1,NUP50,CCDC86,ZYX,MBD3,NUP42,RBM22,ZNF362,ESS2,WBP11,SRFBP1,TOP3B,ZC3H14,NOL7,POLR2D,PAK5,SMNDC1,NEFL |
| 9.453e-04 | -6.96 | PABPC4L (poly(A) binding protein cytoplasmic 4 like) | protein interactions | 132430 | 53 | 26 | 19454 | 5460 |
RPL31,RPL23A,RPL3,RPS24,DGCR8,NOP53,NUP42,FTL,PABPC5,H1-5,H2AX,SOX2,PAIP2B,RBMS2,LARP4B,SRP14,KRR1,PRR3,PAIP1,LYAR,RPL35,RPL19,HNRNPC,TRA2A,ELAVL2,PEA15 |
| 9.453e-04 | -6.96 | IL1B (interleukin 1 beta) | protein interactions | 3553 | 53 | 26 | 19454 | 5460 |
NLRP3,SP1,HSP90AA1,YWHAZ,CMA1,ATG3,CASP4,ATG7,CDK9,IL18,MAP1LC3A,UBE2N,PTPN1,EZH2,VPS4B,SEC22B,IL1R2,VPS28,EGR1,ADRB2,UBE2D3,IL1B,IL1RAP,SQSTM1,EP300,RAB5A |
| 9.453e-04 | -6.96 | ABCC6 (ATP binding cassette subfamily C member 6) | protein interactions | 368 | 53 | 26 | 19454 | 5460 |
SNRPD3,EIF2S1,PRDX2,SNRPD2,PPP2CB,UBE2N,QNG1,AK2,GALE,PSMD1,RPL6,CALR,HSPA5,ROCK2,CRYL1,HADHA,PGK1,RPS28,AKR1A1,FURIN,RPLP0,ADNP,GDI2,EXOSC8,GFPT1,RPL27A |
| 9.466e-04 | -6.96 | DHODH (dihydroorotate dehydrogenase (quinone)) | protein interactions | 1723 | 40 | 21 | 19454 | 5460 |
GMPPB,CDC16,ANAPC13,PLP2,TMEM95,GINS4,ACACA,TAF2,RIT1,CYC1,VAC14,SDHC,SSBP1,BAP1,CTNNBL1,SLC31A1,KRAS,FKBP8,FTL,MT2A,NDUFS8 |
| 9.466e-04 | -6.96 | C1orf52 (chromosome 1 open reading frame 52) | protein interactions | 148423 | 40 | 21 | 19454 | 5460 |
MCAT,LMNB1,MAD2L1BP,LMNA,RPA2,GPX7,CBX3,DNAJC8,DENND2D,PRPF19,APEX1,MAD2L1,MED17,FGF12,NUP50,RAB5A,BAG2,EWSR1,SYT2,COX4I1,RPA3 |
| 9.474e-04 | -6.96 | ETV6 (ETS variant transcription factor 6) | protein interactions | 2120 | 100 | 43 | 19454 | 5460 |
HDAC6,PPIL4,SPATA2,KLHL9,WWP2,SIN3A,WDCP,ETV6,EGLN3,SUMO2,TRAF2,SOCS3,SOX2,TNRC6C,CRKL,IRF8,NFE2L2,VPS26B,AP1M1,MDC1,FLOT1,NTAQ1,MYC,SEC13,CEP85,LRP6,XPOT,BRCA1,ZMYM2,UBE2I,MID1IP1,MAD2L1,SMURF1,VIRMA,ESR2,SNRNP40,TIMM13,NUP62,SUMO1,LMNA,GRPEL1,SKP1,HDAC3 |
| 9.474e-04 | -6.96 | AP2S1 (adaptor related protein complex 2 subunit sigma 1) | protein interactions | 1175 | 100 | 43 | 19454 | 5460 |
AP2M1,RAN,UBB,ESR2,CETN2,OCRL,FCHO2,LAMTOR3,HDAC6,INSYN1,DNAJC5,MYC,CUL3,ZCCHC10,AP2A1,EPHA2,DCAF11,UBE2H,RIT1,SHC1,MYO6,CCDC32,RPA3,DVL2,HNRNPA2B1,RNF11,UTP25,RNF41,TNF,KRAS,NECAP2,ARFGAP1,H1-5,TOP3B,RAF1,ATG16L1,GPBP1L1,NUPR1,SGIP1,ACACA,RPA2,PAK5,NECAP1 |
| 9.476e-04 | -6.96 | positive regulation of intracellular protein transport | biological process | GO:0090316 | 93 | 42 | 18204 | 5365 |
HYAL2,RAB29,OAZ3,EFCAB7,CDC42,OAZ1,VAMP2,EP300,CHRM1,MDM2,PDCD10,EDEM1,JAK2,HCLS1,SMAD3,MAVS,SAR1B,IFNG,TMEM30A,EDEM2,HSP90AA1,SFN,PRR5L,OAZ2,TM9SF4,CD81,LEP,CAMK1,PSEN1,PDCD5,PIK3R1,RAN,RBM22,PIK3R2,HDAC3,CTDSPL2,JUP,BAG3,DMAP1,IL1B,ANP32B,CDK1 |
| 9.488e-04 | -6.96 | CDK18 (cyclin dependent kinase 18) | protein interactions | 5129 | 126 | 52 | 19454 | 5460 |
CDKN1A,HEXIM1,ACAA2,LARP4B,CDK1,P3H1,PML,CCND3,VPS28,DNLZ,GNB4,FBXW7,CCDC85B,TTC23,GORASP2,COL1A2,HSP90AA1,YWHAZ,CHTOP,CCT2,SFXN2,RPL37A,TRIM27,PNMA1,STUB1,TRAF1,DYRK1A,PPP5C,CTSB,TRIM54,EEF2,TRAF2,CCT5,UBL4A,MTA2,CDK5,CCT8,S100B,YWHAH,YWHAG,FGR,YWHAB,SEC23A,FAAP100,MAGED2,HOMER3,FUBP3,PPP2CB,HSP90AB1,CCT7,TCP1,CDK17 |
| 9.488e-04 | -6.96 | USP33 (ubiquitin specific peptidase 33) | protein interactions | 23032 | 126 | 52 | 19454 | 5460 |
TMPO,DNAJC1,SPINT2,HSD17B11,KRR1,KCNA2,USP15,EXOC2,BECN1,TRAF6,ELOC,CTNNB1,LRRTM1,SLC25A46,EDEM1,ATG9A,PCGF6,TRIM63,KRAS,LDLRAD4,TMT1A,GNAI3,RPN1,STIM1,DUSP1,TRIM54,RALA,SEC61B,DIO2,CHRM5,STN1,CGRRF1,GABRG2,GPR17,CUL3,MYC,RALB,AKT1,PXMP2,ADRB2,DERL1,AKAP1,RAB5A,TLR2,SAMM50,DRD3,SSR1,LMNA,VAPB,ST7,SEC62,OTULINL |
| 9.488e-04 | -6.96 | UQCRH (ubiquinol-cytochrome c reductase hinge protein) | protein interactions | 7388 | 126 | 52 | 19454 | 5460 |
SERPINB1,SLC15A2,CHCHD4,HMOX2,MYC,UQCRQ,ATP5F1B,TUBB,NDFIP1,SLC11A2,LMBR1L,UQCRC2,CYC1,DCTN4,ARMCX3,HCST,UQCRC1,BORCS6,ATG16L1,MPV17,G3BP2,PRRG1,PDHB,RPL4,PHB2,RAB5A,DCTN3,SQSTM1,DCTN6,POR,NDUFV2,TSPAN10,EMC4,NDUFS8,EGLN3,CORO1C,AIFM1,EEF1B2,PHB1,COX4I1,CRELD1,NDUFA12,CYB5B,KLRC2,NDUFS3,PDHA1,EEF1A1,EEF2,EMC8,EMC2,ACTR1B,SFXN1 |
| 9.502e-04 | -6.96 | DNA-templated transcription | biological process | GO:0006351 | 529 | 189 | 18204 | 5365 |
SNAPC3,GPBP1L1,MED29,PAX6,WNT10B,POLR3F,CD28,CBFB,MED27,POLR3H,GTF2A1,NCAPG2,THAP1,PAAF1,IRF9,ZMPSTE24,HDAC3,SMAD2,GTF2H4,TAF2,CREBL2,TAF5L,APOBEC3F,WDR82,POLR2I,CDC73,NKX3-2,POLR2C,POLR3B,WWP2,CREB1,GTF2F1,MARS1,PADI2,COPS2,FOXP3,POLR2D,GTF2F2,POLR3GL,NFIL3,MED21,BARX2,USP15,SMN1,SMAD1,MED31,TAF11,PPP5C,JAK2,NR1H2,MACROH2A1,KPNA6,POLR1D,RPRD1A,XBP1,SUB1,MTF1,SART3,SOX9,HIRA,CDK12,TOPORS,IL2,CYTL1,RRN3,CDK7,TRIM24,AR,SNAPC5,EP300,DR1,DPY30,ENY2,GTF2B,SIRT7,GTF2H5,SKIC8,TWNK,CTNNB1,SNAPC1,VDR,TCEANC2,RPRD1B,CEBPE,NFKBIB,DHX9,NPM3,PRMT5,MTERF2,FUBP3,PROX1,PRDM4,SMAD4,ZNF345,ADRB2,POLR2L,MNAT1,GTF2E1,NR4A2,EGR1,SMARCB1,IVNS1ABP,BCL9,DRAP1,GTF2I,TCEA2,GTF3C4,PIK3R1,GTF2IRD1,IRF1,DEK,MLF1,PPARG,NIBAN2,SNAPC2,CCNA2,TAF7,TAF10,ERCC3,TP53,MED17,APEX1,VPS72,EPOP,MEF2A,SUPT4H1,ELOF1,DDX5,NCBP2,ADRM1,GTF2H2,ATXN1L,HELT,SMARCA5,POLR1B,TCOF1,KLF4,ATF4,POLR1H,POLR2F,SQSTM1,POLR2G,SUPT5H,TFCP2,NFYA,MED4,FOS,RPAP2,POLR2B,CDK9,SPHK2,WBP2,GTF2E2,NFKB1,TFB1M,SUPT3H,OGG1,RB1,APOBEC3A,MRPL12,CCNH,GTF3C3,LDB1,CEBPG,NDP,TCEA1,TAF9,TRMT112,MSX1,MED9,ELOC,MED23,PPP1R1B,SSU72,PIR,MED10,PLAC8,BCL6,MED30,MED11,FOXA3,SGF29,PKNOX1,EAF2,HINFP,S100A10,APOBEC3C,MED22,GTF2A2 |
| 9.522e-04 | -6.96 | positive regulation of muscle cell apoptotic process | biological process | GO:0010661 | 36 | 20 | 18204 | 5365 |
MIR24-1,IL12A,IL12B,TP53,IFNG,MIR28,STUB1,MIR320A,MIR17,MIR140,SOD2,MIR34A,ATF4,SMAD4,MIR195,PDCD4,PPARG,MIR16-1,MIR1-1,CAPN2 |
| 9.522e-04 | -6.96 | positive regulation of cardiac muscle hypertrophy | biological process | GO:0010613 | 36 | 20 | 18204 | 5365 |
MEF2A,BECN1,ROCK1,IL6ST,MIR21,HAND2,MIR20A,PDE9A,MIR214,MIR17,PPP3CA,MIR34B,IGF1,PRKCA,MIR208A,ROCK2,PARP2,MTPN,MIR34C,ADRA1A |
| 9.545e-04 | -6.95 | Uptake and function of diphtheria toxin | REACTOME pathways | R-HSA-5336415 | 6 | 6 | 10285 | 3229 |
HSP90AA1,HBEGF,HSP90AB1,TXNRD1,CD9,EEF2 |
| 9.589e-04 | -6.95 | LMNB2 (lamin B2) | protein interactions | 84823 | 222 | 84 | 19454 | 5460 |
USP2,SLC25A46,DPP4,GPRASP2,RHOG,TUBG1,RCHY1,PTPN1,RAC2,EED,HSD17B11,HYPK,PRNP,RHOH,KCTD10,DNAJC1,ARL6IP5,ANKRA2,TMPO,MTCH2,TOP3B,CA8,THAP1,FNTB,SOX2,DNAJC25,CHMP4C,EZH2,RPN1,NUPR1,PDE6D,TMT1A,NAE1,ABCE1,VDAC1,MNAT1,FKBP8,OVOL1,FOXA3,MYC,USP14,DEPDC1B,RHEB,LMNB1,SPOP,DNAJB6,GTPBP2,UBE2H,MAPRE1,DLST,CCNF,LMBR1L,SEC61B,TRIM27,RHOJ,VIRMA,ESR2,SEC63,LRIF1,CCND1,ING5,SPTBN1,CFTR,ST7,RND2,SEC62,CCNH,CDC42,RFXANK,SSR1,LMNA,JUP,MFAP1,UBE2M,TFIP11,KLC2,SIRT7,BANF1,XRCC5,SOD1,RNF113A,STAU1,TSR3,POLA2 |
| 9.591e-04 | -6.95 | HECTD1 (HECT domain E3 ubiquitin protein ligase 1) | protein interactions | 25831 | 290 | 106 | 19454 | 5460 |
TP53,MAP1LC3B,METTL15,EHD4,SEM1,TOLLIP,KPNA2,PPIL4,COPS5,EXOC2,USP15,SSBP1,AIFM1,HRAS,DBT,CPSF4,WDR83,UBA52,SNRNP27,SPMIP6,ZCCHC17,ACACA,HECTD1,RPA3,BTBD10,SIRT7,DLAT,SQSTM1,NF2,PDHB,FBXW7,SMC4,SMARCA5,EXOC5,GMNN,NONO,ZNHIT3,PDCD4,IGF2BP1,AP3S2,CCNF,CINP,RPS3,GSK3A,ZNF622,BUB3,RPGRIP1L,UBE2L3,VIRMA,SRPK2,TOP3B,EEF2,TUBB4B,PDHA1,HSPD1,SLC25A5,CCT8,CDK5,PSMD12,GTF3C3,POLDIP3,RFC3,IMMP2L,AHCYL1,PRDX1,PSMD3,DPY30,YWHAH,YWHAG,CTNNB1,BTF3L4,EXOC1,UBE2D1,HSPB1,YWHAB,ARMC8,SIN3A,KRT8,EIF2S1,HNRNPL,DIRAS3,EGLN3,HSP90AB1,CCT7,KCTD12,LXN,PCLAF,EP300,UBE2D3,PHB2,NRBF2,SKP1,SFN,CUL3,RIOK2,CPSF2,YWHAZ,FBXW11,THOC6,PAPSS2,LMBR1L,NFKBIA,RPS9,PRDX2,EIF4A2,MTM1 |
| 9.592e-04 | -6.95 | ubiquitin-protein transferase activity | molecular function | GO:0004842 | 446 | 164 | 18094 | 5411 |
UBE2B,TRIM34,HUWE1,RNF39,MED31,GID4,RNF7,RNF133,ZNRF1,TRIM15,CDC42,TRIM8,TNFAIP1,RNF40,MSL2,UBE2G2,COP1,TRIM44,CUL3,RNF8,UBE2D1,HECTD1,UBE2S,TRIM11,TRIM37,TRIM62,STUB1,HERC3,TRIM10,TRIM27,MED30,RNF14,UBE2M,FBXO30,SYVN1,RNF148,ANKIB1,TRIM45,G2E3,TRIM32,UBE2N,SHPRH,UBR7,HECW1,RBCK1,DTL,UBE2E3,ANAPC4,TRIM63,RNF128,RNF113A,HECTD3,TRIM23,RNF144B,FBXO7,RNF103,RING1,UBE2H,MED21,UBE3A,UBE2D3,NOSIP,LNX2,MED27,MARCHF3,MUL1,UBE2K,TOPORS,FBXO3,BFAR,MARCHF9,RNF20,RNF141,TRIM6,PRPF19,TRAF6,CDC23,ASB1,RNF152,PPP1R11,RNF11,FBXO25,RC3H2,WDSUB1,ANAPC11,TRIM5,FBXL3,BRCA1,SIAH1,MED11,WSB1,WWP2,CBLL1,RNF126,RLIM,RNF41,FBXO44,MARCHF4,MARCHF5,RNF10,TRIM35,CBL,RNF187,NT5C2,TRIM36,MYLIP,UBE2A,TRAF2,VPS18,MAEA,TRIM26,UBE2W,KLHL9,RAG1,RNF208,RNF167,KCTD10,RNF115,CCAR1,BIRC2,IRF2BP1,MDM2,BRAP,FBXO11,WWP1,RNF34,SIAH2,RNF182,FBXO22,MED10,TRAF3IP2,RNF181,TRIM24,PELI1,PELI3,PCGF3,IRF2BPL,HERC4,RNF122,RNF146,TRIM54,TRIM68,RNF121,NEURL2,UBE2L3,RNF26,SMURF1,CUL2,RMND5B,RNF139,CDK8,TRIM3,FBXO9,FBXL14,TRIM21,TRIM52,RNF5,AREL1,TRIM22,TRAF7,RCHY1,UBE2E2,MED17,TNFAIP3 |
| 9.654e-04 | -6.94 | urinary_tract-bladder-other-neoplasm | COSMIC cancer mutations | urinary_tract-bladder-other-neoplasm | 8 | 7 | 16828 | 4835 |
PIK3R1,HRAS,MET,KRAS,TP53,PTEN,PIK3CA |
| 9.655e-04 | -6.94 | TBC1D24 (TBC1 domain family member 24) | protein interactions | 57465 | 35 | 19 | 19454 | 5460 |
TP53,CUL3,TOP3B,TNFAIP3,GPAM,GNG2,RPA2,ATP6V1D,NTRK3,RASSF8,NFKBIA,ACBD7,RPA3,S1PR4,HRAS,TMEM185A,PRNP,ATP6V1G1,TLR1 |
| 9.655e-04 | -6.94 | DYNLT3 (dynein light chain Tctex-type 3) | protein interactions | 6990 | 35 | 19 | 19454 | 5460 |
MAPRE1,EZH2,NIF3L1,NUDCD3,MGARP,CDH11,RPS29,CCL28,PAFAH1B1,ZC3H14,DYNLT3,RPS16,DYNC1I1,VDAC1,DYNLL1,DYNC1I2,DCTN3,RPS3,TESC |
| 9.655e-04 | -6.94 | GRIK1 (glutamate ionotropic receptor kainate type subunit 1) | protein interactions | 2897 | 35 | 19 | 19454 | 5460 |
PICK1,SEPTIN7,DLG4,DLST,HOMER1,SRI,HNRNPL,LDB2,ZNF592,DNAJB9,ST13,GORASP2,TAAR1,COPS5,SNAPIN,CSK,HSP90B1,GRIK1,SDCBP |
| 9.655e-04 | -6.94 | MBL2 (mannose binding lectin 2) | protein interactions | 4153 | 35 | 19 | 19454 | 5460 |
PSMB7,CALR,PSMB2,PSMB3,EGLN3,MAD2L1,RASL11A,PSMA1,PSMA2,PCGF3,MBL2,TGIF2LX,FBXO11,PSMB1,DCK,PSMA3,PSMA6,FUBP3,PSMB4 |
| 9.661e-04 | -6.94 | YPEL5 (yippee like 5) | protein interactions | 51646 | 72 | 33 | 19454 | 5460 |
DDIT4L,JPH4,EMILIN3,SOX2,CTDSP1,ADAMTS1,CTSA,MAEA,GID8,MKLN1,DDX5,RMND5B,H1-6,PSMA1,RANBP10,LECT2,CNRIP1,PFDN5,SHC3,FBXO7,COPS5,MRPL18,NOVA1,STK11,UBE2H,ARMC8,WDCP,SYNCRIP,MRPS28,ZNF655,FZR1,EGLN3,ESR2 |
| 9.661e-04 | -6.94 | Smn1 (survival motor neuron 1) | protein interactions | 20595 | 72 | 33 | 19454 | 5460 |
BAG2,EGFL7,RNF5,COIL,TMEM209,SMN1,RAF1,SEC22B,SLC35E1,TRAM1,LSM10,TIMM23,GEMIN7,ELOVL1,COX4I1,SNRPD1,PHAX,SNRPD2,KRT8,TXN,SNRPD3,DERL2,NOP9,PTDSS1,TIA1,PRKACB,ATP5F1A,SNRPB,COX11,SNRNP70,GEMIN8,ELAVL4,GGCX |
| 9.679e-04 | -6.94 | MGA (MAX dimerization protein MGA) | protein interactions | 23269 | 219 | 83 | 19454 | 5460 |
ALKBH3,CCND1,CDK7,KLF12,MXD1,RPA2,KLF3,ADNP,E2F6,RPA3,HSPB2,YAF2,PCGF2,ZNF692,KDM1A,STAU1,COIL,TRIM52,LSM8,FTL,CDC16,MYC,HNF1B,IRF1,KANSL3,PRPF31,AR,TFDP2,ZBTB38,UBE2H,PELP1,ELK3,LURAP1,TMEM74,ZMYM2,PHF21A,SNRNP40,MAD2L1,LRIF1,CBX5,ESR2,VIRMA,APEX1,MAX,TP53,E2F4,EGR2,CD2BP2,ELF1,TULP3,SMAD1,CBX3,CDK8,CTLA4,CHAMP1,PHC1,PSMC3,LTBR,RUVBL2,RING1,H3C1,PCGF3,CHN2,DYNC1I1,RUVBL1,ASF1A,TRIM37,PAX6,MDC1,PRPS1,RIGI,PCGF6,TAF7,CSNK2A1,SUV39H1,ARHGAP5,LHX2,BRD3,EED,ARL4D,PRNP,EGLN3,KLF9 |
| 9.695e-04 | -6.94 | vesicle docking | biological process | GO:0048278 | 56 | 28 | 18204 | 5365 |
STX6,CFTR,STX1A,STX12,EXOC3,EXOC1,EXOC8,STX17,STX8,VAMP3,EXOC5,BVES,SNAP25,STX16,STX11,STX5,STXBP1,KCNB1,PPFIA3,CAV2,STX7,EXOC2,CPLX2,VPS18,STX10,GNAO1,YKT6,VTI1B |
| 9.695e-04 | -6.94 | monosaccharide biosynthetic process | biological process | GO:0046364 | 56 | 28 | 18204 | 5365 |
G6PC3,SLC25A1,LEPR,CRY1,SLC25A11,SLC25A10,AKR1A1,PGM1,CRTC2,FBP2,PC,ENO2,PPARA,SORD,ATF4,FBP1,MDH1,PGK1,ATF3,AKR1B1,SLC25A12,SDS,SLC37A4,G6PD,PGAM1,ENO1,RGN,PCK2 |
| 9.695e-04 | -6.94 | nuclear envelope organization | biological process | GO:0006998 | 56 | 28 | 18204 | 5365 |
CHMP1A,VPS4A,UBXN2B,PRKCB,CHMP2B,VRK1,PAFAH1B1,CHMP2A,REEP3,TMEM170A,PARP11,REEP4,BANF1,DES,CHMP4C,AKAP8L,LMNB1,TOR1B,UBE2I,VPS4B,CDK1,NSFL1C,CHMP5,CHMP1B,ZMPSTE24,DMPK,PRKCA,LMNA |
| 9.743e-04 | -6.93 | GTF2IRD2 (GTF2I repeat domain containing 2) | protein interactions | 84163 | 10 | 8 | 19454 | 5460 |
GTF2I,TRIM54,CDK20,GTF2IRD1,HSP90AA1,FBXO25,HEXIM1,MEPCE |
| 9.743e-04 | -6.93 | RFESD (Rieske Fe-S domain containing) | protein interactions | 317671 | 10 | 8 | 19454 | 5460 |
CIAO1,QNG1,PRKAB1,MAD2L1BP,PRKAG1,GPIHBP1,AK2,KRAS |
| 9.743e-04 | -6.93 | UL122 (regulatory protein IE2) | protein interactions | 3077563 | 10 | 8 | 19454 | 5460 |
CSNK2A1,CSNK2B,RPS17,ZMYND11,RB1,TP53,HSPA5,DYNLL1 |
| 9.743e-04 | -6.93 | TUL1 (ubiquitin-protein ligase TUL1) | protein interactions | 853832 | 10 | 8 | 19454 | 5460 |
UBE2E2,UBE2W,UBE2N,UBE2V1,UBE2E3,UBE2K,UBE2D1,UBE2D3 |
| 9.752e-04 | -6.93 | response to wounding | biological process | GO:0009611 | 431 | 157 | 18204 | 5365 |
HPS6,NPPC,FOLR1,CD151,STXBP1,NLRP6,JAK2,B4GALT1,FGF1,CDKN1A,NRP1,ILK,MYL12A,CCR1,LCP1,CD34,RAB27A,LMAN1,THBD,CD59,NEFL,CD2AP,DDR1,PRCP,ODAM,CTNNA1,TNR,FLRT3,NDP,CCR2,F2,HBB,GGCX,SOD1,PLSCR1,RAB3A,ACTB,IGF1,NOTCH2,SARM1,SLC7A11,TNF,PDCD10,SMAD3,RAF1,TGFB2,CX3CL1,IL1A,METAP1,SLC1A1,FGF10,SLC1A2,CX3CR1,NPR2,MAP1B,PDIA3,TMIGD3,GPX1,LACRT,CSRP1,FGF7,RAP2B,SYK,WNT7A,PPP3CA,COL3A1,SOX2,ITGB5,KLK6,WDR83,SERPIND1,MPIG6B,CD40,NDNF,PTK7,VPS4B,PDIA2,NOG,PLG,AGER,ITGA2,ABHD2,CHMP2A,TYROBP,SLC6A4,PAX6,EPO,F9,VAV2,EDNRA,BLOC1S3,FZD6,VEGFA,CD36,CHMP2B,AK3,TIMP1,CAV3,POU5F1,UBASH3B,TSPO,NREP,PROS1,CHMP5,C1GALT1C1,FGFR1OP2,JAML,CLDN1,SERPINC1,MSX2,CHMP4C,HBEGF,PAPSS2,CD9,VWF,F10,F7,KCNB1,PIK3CA,SDC4,TLR3,TREML1,P2RY12,BAX,ENPP4,GP9,SERPINA1,IL6,MIR34A,GNAQ,PPIA,VPS4A,SOD2,ADIPOR2,CHMP1A,HSPB1,VASH1,ITGAV,EXT1,P2RY1,COMT,SRC,ADORA3,ELK3,DAG1,LAMB2,CHMP1B,MORN4,CDK1,TFPI,PIK3CG,PPARA,SLC1A3,CD40LG,FKBP10,DDIT3,TLR4 |
| 9.766e-04 | -6.93 | HACD3 (3-hydroxyacyl-CoA dehydratase 3) | protein interactions | 51495 | 216 | 82 | 19454 | 5460 |
RB1CC1,ARMC8,AGR2,DDRGK1,NFKB1,KARS1,IFI16,ADIPOR2,EMC4,PTPN5,LMAN1,SERINC3,FZR1,HNRNPL,CAND1,RHOH,HSD17B11,ARHGAP25,CORO1C,RAC2,PHB1,PLD3,RPN1,EZH2,BZW2,ISG15,FAF2,LGR4,UBL4A,RAF1,TP53,PSEN1,ARHGAP15,TRIM37,TSPAN17,EMC2,IGF1R,UBE3A,NTRK3,UBE2H,ARHGAP19,RHOB,DCAF4,RC3H2,USP14,MYC,CUL3,PPP5C,GNB1,SEC63,VIRMA,ESR2,NDN,CHCHD6,LMBR1L,CCNF,PELO,ACACA,CAV2,MED23,RPA2,SSR1,GRM2,CDC42,SEC62,GABRA1,CFTR,GABARAPL2,ATG16L1,BET1,PGRMC1,UFL1,PHB2,FBXW7,STAU1,NMRAL1,DERL1,RAB9A,EP300,PMAIP1,BAP1,RPA3 |
| 9.766e-04 | -6.93 | CAMK2G (calcium/calmodulin dependent protein kinase II gamma) | protein interactions | 818 | 216 | 82 | 19454 | 5460 |
UBXN6,SIVA1,YWHAH,YWHAG,TIAM1,BECN1,SMAD4,TUBG1,BCL10,YWHAB,NPR2,RCHY1,PPP2CB,THOC2,SMAD3,PSMB1,IGBP1,SH2D1A,ARHGAP25,PRNP,CAMK2N2,SLMAP,RBM42,MRPL11,STRBP,TNPO2,AGPAT5,ACTR1A,PPP2R1A,ACTN4,PNMA2,CAPZA2,TBC1D4,ADCY3,KLHL26,MYO1B,TRIM37,CAMK2G,TRIM26,KRAS,IMMP2L,PAK6,PSMD12,CUL3,FAM163B,FGFR1OP2,MYC,ATF1,YWHAZ,PELI3,MAPRE1,SMAD2,PEA15,HSP90AA1,CAMK2N1,CTTN,GRIA1,UBE2I,PTEN,PHKB,PHF21A,MOB4,PRSS8,DYNLL1,YES1,GPX1,STAT1,APEX1,CYP4F12,TNPO3,SPR,GTF2H4,CNPY3,TIRAP,RPA2,RPA3,BAP1,DNAL4,STAU1,FXR2,KDM1A,CMAS |
| 9.789e-04 | -6.93 | ZCRB1 (zinc finger CCHC-type and RNA binding motif containing 1) | protein interactions | 85437 | 132 | 54 | 19454 | 5460 |
RPL26L1,ZNF574,H1-5,UTP23,NOP53,SF3B1,CCDC86,THOC3,RPS5,RIT1,NSA2,H1-1,RPL26,SNRPB,MYC,RPL7A,RPL19,RPF1,RPL35,RPL13A,SNRPD2,ZMAT5,MACROH2A1,SF3B6,RPS3,FAU,SURF2,SNRPE,H1-3,MAK16,RPSA,E2F4,SRSF4,RPS27A,RPL17,SNRPG,H1-6,KRAS,SNRNP48,RPL23A,RPL31,NOL12,RPS2,H2AC4,SNRNP70,RAB5C,DKC1,SURF6,RPS16,RPS10,PRR3,HP1BP3,THOC2,KRR1 |
| 9.789e-04 | -6.93 | DNAJC17 (DnaJ heat shock protein family (Hsp40) member C17) | protein interactions | 55192 | 132 | 54 | 19454 | 5460 |
CLIC4,ERH,MYG1,CBX5,SNRNP40,SMU1,GCFC2,CYRIB,FAIM,STUB1,TRMT6,RIT1,HNRNPC,MYC,RALB,HSPA14,HSPA5,SAP18,RBM22,WDR3,CWF19L1,KIN,PML,NCDN,HELLS,RPA3,PPM1G,TFIP11,E2F6,CZIB,RPA2,WDR83,CDC5L,CWC15,RPL35A,ARMC1,RCHY1,SRP14,AHSA1,ECD,DDX23,PRPF19,PCGF6,FKBP8,NOC4L,KRAS,H3C1,CDC40,GALC,TCOF1,SART3,DNAJC2,SURF4,ESS2 |
| 9.805e-04 | -6.93 | MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase) | protein interactions | 10797 | 103 | 44 | 19454 | 5460 |
SSBP1,HRAS,PHB1,UBP1,PREP,RFX5,PTEN,LDLR,GATD3,DAPK1,FZR1,TXNDC12,MACROD1,MTG2,MYC,AUH,CUL3,LAMTOR2,TUFM,GCC1,AK2,RHOG,TMEM70,SCFD1,NRP1,UBE2H,HSPD1,PEBP1,MTHFD2L,HSPA8,NMRAL1,HAPSTR1,RNF113A,COX8A,HSCB,UFL1,HUWE1,RER1,LYPLA1,CFTR,LMNA,TFCP2,PDHA1,MTRES1 |
| 9.805e-04 | -6.93 | ARFGAP3 (ADP ribosylation factor GTPase activating protein 3) | protein interactions | 26286 | 103 | 44 | 19454 | 5460 |
TMT1A,SYPL1,CYP2C9,RPA3,RAB5A,HSD17B10,RAB9A,DERL1,IGF1R,RAB3B,TRIM26,FKBP8,ZDHHC17,ARF4,PXMP2,BET1,ARFGAP1,CD14,CFTR,OTULINL,CDC42,CXCL8,SEC62,RAB4A,FGFR1,RPA2,FURIN,ARF1,SEC61B,GJA1,HSD17B11,CAV1,EGLN3,STX6,RAB11A,NTAQ1,LAMP3,XPO1,BICD2,LAMTOR1,RHOG,TPPP3,NTRK3,SMAD2 |
| 9.805e-04 | -6.93 | ALDH4A1 (aldehyde dehydrogenase 4 family member A1) | protein interactions | 8659 | 103 | 44 | 19454 | 5460 |
LDHAL6B,QRSL1,IDH2,GSTP1,MTRES1,FKBP1A,LAP3,CRYZ,PTRHD1,RPA3,FXN,AUH,ACO2,LDHB,PYCR1,MRM2,PMPCA,CFL1,MTPN,CFL2,TUFM,LDHA,CLIC4,TACO1,ENO1,CCR1,SOD2,STK16,ISG15,GLRX5,MPST,HINT2,TST,PMM2,HDAC6,LYPLAL1,ESD,MALSU1,RAB33A,SSBP1,COX4I1,DSTN,FAHD1,GATD3 |
| 9.805e-04 | -6.93 | PDP1 (pyruvate dehydrogenase phosphatase catalytic subunit 1) | protein interactions | 54704 | 103 | 44 | 19454 | 5460 |
CLIC4,DDAH2,ACAT1,ENO1,HERC4,PMPCA,PNOC,ACO2,UNC45A,PRDX6,PCGF2,HSPA8,SOD1,ARCN1,FGFR1,IDH2,KCTD12,NDUFAB1,TPT1,DDAH1,CHST7,SPTBN1,WDR44,DBT,SPTAN1,SPPL3,GATD3,CORO1C,HDHD3,SPRED2,AK2,RHOG,CLEC18A,ERCC3,PRDX1,MPST,ADIPOQ,HINT1,HINT2,ILF2,C1QC,PDHA1,FEN1,CMPK1 |
| 9.806e-04 | -6.93 | Activation of Kainate Receptors upon glutamate binding | REACTOME pathways | R-HSA-451326 | 32 | 19 | 10285 | 3229 |
NCALD,GNB4,GNG7,GNG10,GNG5,GNG11,PLCB1,PLCB2,GNG3,DLG4,GRIK1,GNB1,GNG13,DLG1,DLG3,GNGT2,GNB3,GNG2,GNG12 |
| 9.811e-04 | -6.93 | intracellular monoatomic cation homeostasis | biological process | GO:0030003 | 428 | 156 | 18204 | 5365 |
CCDC47,SLC30A5,CCL1,NPTN,FXN,SV2B,ATP1A3,SLC39A9,STIM1,AQP11,CCDC22,ATP2C1,FATE1,PSEN1,MT1A,CAV1,ATP6V1A,FTL,MAIP1,EDNRA,TMEM199,FKBP1B,SNAPIN,TPT1,B2M,KCTD17,IREB2,CAV3,HEXB,SLC41A1,CHRNA7,P2RY1,KCNJ2,CCL3,VPS33A,ADORA1,CNNM4,HTR2A,CA2,ATP6AP2,TRPC1,PRNP,CCL11,COX11,GRM1,MT1X,SLC25A23,CCL8,ATP6V1D,TM9SF4,ATF4,TMEM165,RNASEK,SLC1A3,FASLG,CYB561,SLC4A10,CACNB2,STOML2,ATP6V0B,CCL5,RMDN3,SLC39A13,ARF1,CLIC4,UBE3A,BAX,ATP1B3,MYC,LAMP2,NEO1,SLC39A7,FTH1,TMEM203,SLC30A7,DMPK,CFTR,PLN,GRIA1,RGN,FRRS1,NDFIP1,SLC12A2,BOLA3,MT2A,CCR2,BOLA2B,F2,VPS54,ATP1B1,FIS1,CCL19,SLC25A27,PICALM,SLC8A1,SOD1,ATP1A2,CNR1,TASL,NPPC,ATP2B4,DISC1,SLC11A2,GLRX5,PML,HSP90B1,CAV2,LACC1,MT1M,BOLA1,CACNB4,PRKCB,CCR1,GPR89A,SLC4A8,SRI,COX19,P2RY4,HFE,ATP6V1G1,CXCL12,KCNMA1,CD40,TMBIM6,CCL23,FTHL17,ACO1,PRND,S100A8,SLC22A17,SLC31A1,SMAD4,MT1E,DRD3,SMDT1,STC1,VAPB,SLC39A10,CHP1,ISCU,ATP6V0E1,IL1A,PPT1,CALR,BOK,SLC1A1,CYBRD1,BAK1,ATP1A1,ATP5F1B,VDR,TF,MT3,TMEM106B,SELENOK,TFRC |
| 9.812e-04 | -6.93 | PGAM5 (PGAM family member 5, mitochondrial serine/threonine protein phosphatase) | protein interactions | 192111 | 256 | 95 | 19454 | 5460 |
ZC3H7A,MIR206,G3BP1,ZBTB16,TUBA1A,B3GNT2,RAF1,POLR2C,EZH2,NME1,CHMP4C,MIR214,MIR141,BRD9,PHB1,EGLN3,YWHAG,DDRGK1,NDC80,WWP2,CBL,MAGOH,BCL2L1,HDAC5,BIRC2,EP300,ASB3,MIR106A,RNF5,UFL1,PHB2,ETF1,PIH1D1,MIRLET7B,GTF2F2,CHCHD3,BTF3,MYC,CUL3,DNAJB6,BRCA1,MAP1B,SNIP1,SFXN1,MEPCE,GALNT2,MDC1,HUWE1,MIR15A,KBTBD4,FBP1,NUPR1,NFE2L2,MIR25,MIR106B,AIFM1,COX4I1,TMPO,ZBTB2,FZR1,COPS5,HDAC6,EDEM1,MIR34A,FGR,BRD3,SNRNP70,SQSTM1,RNF113A,MIR10B,DVL2,BAP1,RPA3,MIR205,SIRT7,MIR107,NF2,FBXW7,CDK7,CFTR,MIR21,HECTD1,LMNA,RPA2,MIR16-1,CCNF,EIF4A3,SMURF1,SH3BGRL,DYRK1A,AR,PPP1CC,UBE2H,DNAJC10,MIR145 |
| 9.835e-04 | -6.92 | negative regulation of phosphorylation | biological process | GO:0042326 | 313 | 118 | 18204 | 5365 |
GNAQ,MIR34A,PPIA,MIR15A,DUSP19,PRDX3,HSPB1,BAX,PDCD4,ROCK1,SFRP1,RTRAF,IFNG,FKBP8,MIR106B,DYNLL1,YWHAG,TAF7,THY1,CTDSP2,TRIM27,PARD6A,PRNP,ZBED3,SOCS4,SPRY1,HEXIM1,PTPN1,MIR132,INPP5K,ANGPT1,ERRFI1,PTPRQ,CEP85,NF2,CAV3,UBASH3B,CDKN2D,CAV1,SOCS3,PAX6,MIR137,INHA,LILRB4,DNAJC3,PAQR3,MIR146A,PSEN1,MIR218-1,NTRK3,MIR212,SFN,PPARG,IGFBP3,PPP2R5A,MIR711,PGR,PKIG,IMPACT,SOCS5,CDKN1B,CNKSR3,SPRED2,NCK1,DUSP1,CDKN2C,HYAL2,GSTP1,BAK1,CHP1,MIR24-1,DUSP3,DUSP22,CAMK2N1,DBNDD1,SPRED1,ADIPOQ,C9orf72,PYCARD,PKIA,GRB10,DUSP10,STK38,STAP1,PRR5L,DKK1,AKT1,IL1B,RGS2,HEXIM2,CORO1C,DNAJC10,PTPN22,DEFB114,ADNP,RB1,TESK1,CDK5RAP3,PKIB,LRP6,MACROH2A1,CDKN1A,TSG101,DUSP6,PTEN,TRIB1,SLC8A1,CRKL,CTDSP1,IL2,PAK2,GADD45A,CAMK2N2,CBL,PID1,GSKIP,RGN,MIR20A |
| 9.836e-04 | -6.92 | HTLV-I infection | KEGG pathways | hsa05166 | 256 | 112 | 7161 | 2463 |
CCND1,POLE3,IKBKB,MYBL2,BCL2L1,CREBBP,FZD4,AKT1,SMAD3,PIK3R2,TGFB3,TNF,POLD2,RAN,PIK3R3,WNT10B,PCNA,CDC20,IL15,WNT7A,VDAC1,POLE4,WNT2,XBP1,PRKACB,SLC25A5,RANBP1,ICAM1,HRAS,IL2,FZD6,DVL2,PPP3R2,LTA,ANAPC4,NFKBIA,TP53,CRTC2,MSX2,CREB1,POLD4,CSF2,TGFB2,NRP1,DLG1,EGR1,RRAS2,CD40,ATF3,MRAS,TGFBR2,IL2RG,MYC,PPP3CA,ANAPC2,CDC23,ELK4,CTNNB1,PTTG1,VAC14,BUB3,CALR,MAP3K3,IL2RA,KRAS,CDC26,PIK3R1,PIK3CA,NFYB,CDC16,BAX,CCND3,MSX1,CDKN2C,IL2RB,SLC25A4,EGR2,STAT5A,CDKN1A,ATF1,LTBR,TSPO,JUN,AKT2,MAD2L1,CDK4,CD3G,RB1,MAP3K14,JAK1,ATF4,EP300,SMAD4,SLC25A31,IL1R2,FZD3,ADCY3,XPO1,FOS,ANAPC11,SMAD2,TP53INP1,IL6,POLB,IL15RA,VDAC2,NFKB1,AKT3,TERT,ELK1,ADCY2,SLC2A1 |
| 9.836e-04 | -6.92 | HTLV-I infection | KEGG pathways | ko05166 | 256 | 112 | 7161 | 2463 |
PIK3R3,PCNA,WNT10B,POLD2,RAN,TNF,WNT2,VDAC1,POLE4,IL15,WNT7A,CDC20,FZD4,POLE3,IKBKB,MYBL2,BCL2L1,CREBBP,CCND1,TGFB3,PIK3R2,AKT1,SMAD3,ATF3,MRAS,EGR1,CD40,RRAS2,DLG1,NRP1,ELK4,CTNNB1,PPP3CA,ANAPC2,CDC23,TGFBR2,IL2RG,MYC,ANAPC4,NFKBIA,HRAS,IL2,FZD6,DVL2,PPP3R2,LTA,SLC25A5,ICAM1,RANBP1,XBP1,PRKACB,CSF2,TGFB2,MSX2,CREB1,POLD4,TP53,CRTC2,IL2RB,MSX1,CDKN2C,BAX,CDC16,CCND3,PIK3CA,NFYB,MAD2L1,CDK4,LTBR,TSPO,JUN,AKT2,CDKN1A,ATF1,SLC25A4,EGR2,STAT5A,CALR,PTTG1,VAC14,BUB3,PIK3R1,CDC26,KRAS,MAP3K3,IL2RA,VDAC2,IL15RA,TP53INP1,IL6,POLB,ANAPC11,SMAD2,SLC2A1,ELK1,ADCY2,TERT,AKT3,NFKB1,SLC25A31,IL1R2,EP300,SMAD4,JAK1,ATF4,CD3G,RB1,MAP3K14,FOS,XPO1,FZD3,ADCY3 |
| 9.850e-04 | -6.92 | TTN (titin) | protein interactions | 7273 | 213 | 81 | 19454 | 5460 |
ERP29,EWSR1,HNRNPA2B1,RBM3,RNF167,NEK9,SAR1B,HNRNPDL,UBE2A,MEPCE,TRIM63,HSPE1,ATP5F1D,KRAS,NEDD8,HNRNPF,TULP3,ACTN4,TUBA1A,MAP1LC3B,ITGB5,SH3GLB1,TAB2,CHMP4C,GANC,KRT8,NEO1,MAP1LC3A,FBXO32,PHB1,RPL12,TOP1,ARF6,FZR1,COPS5,HSPB8,HMGA1,H2AC4,AGR2,SQSTM1,HSPB2,DVL2,BAP1,GABARAP,PIAS1,UGP2,ADRB2,SRSF2,ATG16L1,MTMR6,H1-5,ANXA7,HEXIM1,DYRK2,MAP2K1,CRYAB,VAV2,LMNA,UBE2I,ALB,ENO1,STUB1,OPTN,IRF2,SRPK2,SNRNP40,TCAP,ATP5F1B,TRIM54,PYGM,H2BC9,CUL2,RAB11A,CUL3,MYC,CALU,UBE2H,DNAJB6,SP1,BRCA1,POMP |
| 9.854e-04 | -6.92 | innate immune response | biological process | GO:0045087 | 741 | 257 | 18204 | 5365 |
RPL39,DAPK3,AKAP1,IFNGR1,IRF3,STX8,PELI3,MATR3,TMED1,MX1,BCL10,APOBEC3D,MIF,BPIFB3,CCL3,VPS26B,TRIM34,APOBEC3G,CDC42,PYDC2,DAPK1,IFNAR1,IFNA10,RSAD2,PI3,IL12B,TREML1,FCER1G,DDX1,MX2,TRIM68,TLR3,RNASE6,FGR,POLR3B,DEFB124,G3BP1,CNPY3,CCL5,G3BP2,MIR146A,NLRP9,IFNA2,TRIM26,PLPP6,CLDN1,AQP4,CD46,APOBEC3F,LILRA2,DHX16,JAK1,SH2D1A,SYNCRIP,MYD88,WFDC5,SLPI,TLR9,IFNK,IFIH1,POLR3H,MSRB1,CDC42EP4,TAX1BP1,OPTN,ZYX,POLR3F,NMI,MAVS,CLEC6A,RIGI,SIN3A,TRIM11,IFNB1,IFI27,LYAR,CHID1,ISG20,HCFC2,TANK,JCHAIN,WFDC13,ISG15,TLR6,UAP1,IFNA13,TTC4,C1QC,DHX9,TRIM8,NCK1,TMEM106A,DEFB116,DEFB1,FCN2,FBXO9,CLPB,CD209,UBE2W,SRPK2,KLRD1,UBE2N,MIRLET7B,ATP1B1,IFI35,STAT2,TUBB4B,CD14,EIF2AK2,CYBC1,TOLLIP,RPL13A,CDC42EP2,TRIM22,CCDC92,RAB27A,OAS1,DEFB114,FCGR1A,MRC1,CHGA,IRF8,FOSL2,LACC1,DHX15,TIRAP,TRIM29,BST2,STAT1,H2BC11,NLRP6,JAK2,IRF7,TLR7,STXBP1,USP14,TLR4,IFI6,FASLG,TRIM27,SEC14L1,NONO,TFEB,TRIM21,PIK3CG,CD58,HEXIM1,PHB2,TRIM35,SRC,IL18,TMEM33,PRDX1,LGR4,H2BC12,TMEM45B,CAMP,ENDOD1,PRKRA,AZI2,CLEC7A,TP53,IFNG,FAU,SERINC3,CD47,IL17F,APOBEC3H,ACTR2,BPIFB1,PPARG,SLC15A2,TLR8,IFI16,IRAK4,PQBP1,IRF1,TNFAIP8L2,NQO1,TRIM10,SAMHD1,IL23A,YTHDF2,SDHAF4,TRIM15,GAPDH,CYP27B1,IKBKB,IL34,TICAM1,LGALS3,TLR1,TRIM5,IL1RAP,PYCARD,APOBEC3C,S100A8,OTULIN,CD40,NLRP1,MBL2,CD1D,SYK,CLU,CH25H,HMGB1,PHB1,YES1,LY96,TRIM6,PDE12,TRIM62,VAMP7,TRAF2,CX3CR1,TRIM32,NMBR,DEFB115,KLRC2,RAF1,TNF,SARM1,IFIT2,CD2,DEFB121,TBK1,XRCC5,VAMP3,AIF1,TLR5,SFTPD,TIFA,CEBPG,TLR10,TICAM2,TLR2,RARRES2,TRAF6,NLRP3,APOBEC3A,CITED1,TRIM23,NLRP2,CGAS,NFKB1,CASP4,RNASET2,ARG2,APOBEC3B,TUBB,PML,CCL2,PSPC1,CXCL10,TASL,VAMP2,TNFRSF14 |
| 9.886e-04 | -6.92 | African trypanosomiasis | KEGG pathways | ko05143 | 34 | 21 | 7161 | 2463 |
FAS,IDO1,IFNG,PRKCB,PLCB2,HBB,MYD88,GNAQ,TNF,IL18,HBA1,IL1B,FASLG,IL6,ICAM1,IL12A,IL12B,PRKCA,TLR9,IL10,PLCB1 |
| 9.886e-04 | -6.92 | African trypanosomiasis | KEGG pathways | hsa05143 | 34 | 21 | 7161 | 2463 |
IDO1,IFNG,FAS,PRKCB,PLCB2,HBB,MYD88,GNAQ,IL18,TNF,HBA1,FASLG,IL1B,IL6,ICAM1,IL12A,IL12B,TLR9,PRKCA,IL10,PLCB1 |
| 9.887e-04 | -6.92 | C4orf3 (chromosome 4 open reading frame 3) | protein interactions | 401152 | 86 | 38 | 19454 | 5460 |
LMNA,SLC35E3,CCDC47,TMEM101,TIMMDC1,TMEM45A,BCS1L,SYNPR,VTA1,RIGI,JAGN1,YIF1A,PTGES,SLCO3A1,DEGS1,STX1A,MFSD14B,AQP2,TM4SF19,SCN3B,PLEKHO1,FAM174A,SLC41A3,RHCG,REEP4,MMD,SLC25A31,LY6G6C,TMEM45B,TMEM237,TMEM248,SSMEM1,ELOVL4,CYBC1,RETREG3,CLDN9,HSD17B11,SLC19A3 |
| 9.887e-04 | -6.92 | TOM1L1 (target of myb1 like 1 membrane trafficking protein) | protein interactions | 10040 | 86 | 38 | 19454 | 5460 |
CCDC47,TP53,CTXN1,PPME1,TMEM174,HGS,P3H1,VAV2,RPRD1B,CTLA4,ACTR2,CWF19L1,ARPC2,MRPS7,RAB18,TOLLIP,CAV3,COPS7A,CSK,PIK3R1,NDC80,OSGEP,NIF3L1,CRTAP,TSG101,NRSN1,TMEM74,PWP2,PELP1,TUBA1B,SURF2,CAV1,SRC,TMED9,HNRNPL,MAP3K3,PHYH,MANSC1 |
| 9.911e-04 | -6.92 | GABA synthesis, release, reuptake and degradation | REACTOME pathways | R-HSA-888590 | 19 | 13 | 10285 | 3229 |
SLC6A11,SLC32A1,CPLX1,VAMP2,HSPA8,DNAJC5,STXBP1,SNAP25,RAB3A,GAD2,SLC6A1,STX1A,SLC6A12 |
| 9.916e-04 | -6.92 | TMPRSS4 (transmembrane serine protease 4) | protein interactions | 56649 | 309 | 112 | 19454 | 5460 |
NCR3LG1,CDK5RAP3,TMEM30A,C2CD2L,RAB1B,COCH,OSBP,PTK7,MPDU1,XPO5,S100A8,STX5,VAMP2,TAPT1,PLD3,MACO1,STBD1,NEU1,EMC10,PCDH19,ACTN4,TMEM59,FAF2,ERLIN2,EPHA4,VDAC1,ETFA,NDUFA4,CGRRF1,SLC38A1,VEZT,GGH,TIMM21,SYNE4,RPL7L1,ALG5,NDUFAF4,ATP6AP2,B4GAT1,CHP1,ATP5PO,CTBP1,HEXB,CSNK1A1,NDUFA5,ERVFRD-1,TOMM22,TOR1AIP2,PGRMC1,EDEM3,RAB6A,UFL1,ITGAV,CXCR4,TMEM106B,POR,DNAJC7,AGPAT1,TMEM199,DHRS7,DNAJC1,ARL6IP5,FNDC9,ITGA6,SSBP1,TFRC,NDUFS3,GNAI3,PREB,YTHDF2,ERLEC1,TF,GALNT2,FKBP8,NSDHL,STX8,SLC25A10,SFXN1,ATP2B4,CLEC7A,STX18,IGF1R,TMX3,ATP1B3,TDP1,XPOT,NPTX1,CHPF,CNNM4,HMOX2,SLC25A4,CDIPT,SRP54,SEC61A1,CALML5,EPCAM,LMNA,STX17,HSP90B1,MET,TM9SF1,CHPF2,CLRN1,RABL3,ARHGAP1,AIF1L,BNIP3L,MAIP1,TEX264,ITM2B,RAB9A,SPCS2 |
| 9.919e-04 | -6.92 | RNF126 (ring finger protein 126) | protein interactions | 55658 | 135 | 55 | 19454 | 5460 |
LRWD1,EGLN3,MDM2,G0S2,TSG101,EEF1AKMT3,UBE2N,USP15,UBE2D1,USP2,UBE2E2,CENPP,MSH6,RNF20,SEM1,TRIM26,TRIM11,SLC25A5,FAF1,RNF126,SART3,RNF8,GDE1,GFPT1,FAF2,TP53,RRM1,NAA15,UBL4A,UBB,TAX1BP1,PTEN,CSNK2B,LMBR1L,FXN,UBE2H,XPOT,ABCG2,MYO6,TRIM23,UBE2E3,MCM4,SFN,CUL3,PSMB2,TRIM52,MIEN1,UBE2D3,SCN1B,XRCC5,NBN,CDKN1A,NUDT3,CRYM,UBL3 |
| 9.924e-04 | -6.92 | G2E3 (G2/M-phase specific E3 ubiquitin protein ligase) | protein interactions | 55632 | 12 | 9 | 19454 | 5460 |
TRIM54,HNRNPL,RPS15,HSP90AA1,LST1,SPECC1L,TPT1,EFHD1,WDR6 |
| 9.924e-04 | -6.92 | ICA1L (islet cell autoantigen 1 like) | protein interactions | 130026 | 12 | 9 | 19454 | 5460 |
HGS,TNPO3,HNRNPL,GCC1,PICK1,MTDH,CSK,LMO2,DPY30 |
| 9.924e-04 | -6.92 | GNG11 (G protein subunit gamma 11) | protein interactions | 2791 | 12 | 9 | 19454 | 5460 |
GNB3,FOS,REP15,ZHX1,PDCL,GNB4,SMURF1,GNB1,GNAI3 |
| 9.924e-04 | -6.92 | RWDD1 (RWD domain containing 1) | protein interactions | 51389 | 12 | 9 | 19454 | 5460 |
XPO1,MAP3K14,EP300,HSPA14,NUDT18,DRG1,DNAJC1,DRG2,DNAJC2 |
| 9.986e-04 | -6.91 | Cell Cycle, Mitotic | REACTOME pathways | R-HSA-69278 | 514 | 194 | 10285 | 3229 |
ANAPC4,PTTG1,GORASP2,NUF2,SEM1,CEP41,ACTR1A,PSMB4,ANAPC11,CKS1B,PRIM2,LMNB1,RPS27A,PPP1CC,H2AC6,PSMC3,TP53,TUBA1A,H2AB1,SSNA1,MCM8,PSMA6,AKT3,PAFAH1B1,CETN2,EP300,UBA52,SEC13,GMNN,DYNC1I2,PPP2R5A,CEP70,LEMD3,RFC2,PSMB3,PPP2R5E,CCNH,PSMA5,RFC3,FZR1,RFC5,PSMD6,ANAPC2,PSME2,UBE2D1,CENPM,CCNA2,MIS12,TFDP2,NUP35,CDKN2C,H2BC1,SKA2,PCNA,POLA2,CCNB1,H2AZ1,MYC,POLE4,H2AZ2,FKBPL,CDKN1A,GINS3,H2AC7,NUP107,MYBL2,MAPRE1,RBBP4,DYRK1A,ARPP19,PSMD7,SKP1,DSN1,FBXL7,SMC4,PRKCA,CDC26,ORC5,CDKN1B,CDKN2D,PSMA3,PSMB5,H3C1,PSMB7,PSMD3,RPA2,TMPO,POLD2,FBXW11,PSMB10,PSMC5,SPC24,H2BC17,BANF1,CENPL,CCND3,H2AC4,TUBB4B,NUP62,MIR484,CDC23,ORC6,PSMD4,MCM3,PSMA1,PSMC1,NDC80,NCAPG2,B9D2,MAD2L1,HSP90AA1,AKT1,MCPH1,TUBB,PSMB2,PSMD1,NUP42,KIF2A,CDC7,HAUS2,PPP2CB,MNAT1,GINS4,CCND1,PSMD10,CSNK1E,PPP1CB,VRK1,PPP1R12A,LMNA,RAD21,POLE3,BIRC5,NEK2,NDE1,POLD4,HSP90AB1,E2F4,H2BC14,MAX,NUP153,PSMB9,ANAPC15,RPA3,OPTN,RAB2A,RFC4,TYMS,NEK9,H2BC9,CSNK2A1,DYNLL1,H2AC14,PSMD12,ANAPC16,PRKCB,NUP37,CDK6,XPO1,AKT2,CENPP,H2AJ,YWHAG,FEN1,H2AX,H2BC12,PSME1,CDK7,CDK1,PPP2R1A,UBB,PSMD14,RB1,NEK7,PSMC4,TUBG1,CDK4,NUP50,PSMB1,RAB1A,RAB1B,CDC20,CDC16,CSNK2B,SKA1,H2BC11,BUB3,PSMA2,PSMB6,MCM6,PSMB11,MCM4,PSMA4,DCTN3 |
| 1.001e-03 | -6.91 | TXNDC5 (thioredoxin domain containing 5) | protein interactions | 81567 | 207 | 79 | 19454 | 5460 |
UBE2V1,TULP3,RAF1,RBPJ,KLHL26,SERPINA1,GNAI3,NUPR1,PLS3,EZH2,HSPA13,GDI2,SEPTIN7,TRIP4,RAB1A,RNF20,ROCK2,DNAJC30,CSE1L,YWHAG,ZNF207,DPP4,GMPPB,FAM20C,PTPN5,ANKMY2,AGR2,XPO5,EED,ATP6V1A,CD274,NUP35,HSP90AB1,DHX15,DCUN1D1,DNAJB9,SNRPD3,PRNP,SEC62,EDEM3,CFTR,JMJD8,UBE2M,HEXIM1,PIH1D1,RPA2,METTL14,HSPA8,PMAIP1,RNF113A,BAP1,DNAJC3,TMEM106B,PRPF4,HSPA5,UNC45A,GPC1,RNF40,HMGCS1,AR,MGAT5B,MYC,CARS1,LDHB,CUL3,COP1,HSP90AA1,CALU,UBE2H,SPOP,TRIM23,DNAJC10,SMU1,SEC61B,MSN,VIRMA,TXN,TMOD3,PRDX2 |
| 1.003e-03 | -6.90 | NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10) | protein interactions | 4705 | 138 | 56 | 19454 | 5460 |
NDUFC2,AMACR,RPA3,MME,BMPR1A,RHOU,ABCC2,NDUFS2,HSCB,RNF5,KDM1A,DHRS4,RND2,GABRA1,CDC42,MPV17,NDUFA5,MAP2K1,RPA2,QRSL1,PHF21A,MIDEAS,CCNF,ESR2,MAD2L2,UQCRQ,TAX1BP1,MRM2,CUL3,COX6B1,NDUFB7,NRP1,COX8A,NDUFA4,BCKDK,HSPD1,MDC1,DNAJC30,LGR4,RAF1,B3GNT2,NDUFA12,NDUFS6,ACTR2,NDUFS3,HDAC11,PDHA1,NDUFA1,FAHD1,COX4I1,PHB1,SDHB,EGLN3,RHOH,NDUFV2,SAT2 |
| 1.004e-03 | -6.90 | response to estradiol | biological process | GO:0032355 | 118 | 51 | 18204 | 5365 |
ITGA2,LEP,MBD3,UGT1A1,SLC6A1,WNT7A,KCNJ11,ERRFI1,HSPA8,AIFM1,MAP1B,PCNA,IGF1R,SFRP1,GH1,HNRNPD,FGF10,CTNNB1,GJB2,CRHBP,OXTR,CRYAB,SOCS2,GPX1,TACR3,F7,H2AZ1,CALR,IL10,PTGFR,HTR5A,MSX2,CCNA2,CDKN1B,GRIA1,NQO1,CD38,GPX4,CYP1B1,TACR1,RAMP3,UCN,ESR2,EZH2,RUVBL2,OGG1,OPRL1,STXBP1,SLC6A4,TXNIP,MECP2 |
| 1.006e-03 | -6.90 | SIRT1 (sirtuin 1) | protein interactions | 23411 | 388 | 137 | 19454 | 5460 |
MRPS17,IMMP2L,CHCHD2,RBBP7,PTPN4,SATB1,JAK1,EWSR1,MEF2C,ZYX,HSPD1,MTA2,EZH2,FGF10,JUN,GABARAPL1,DNAJC25,TULP3,SAP30,VDR,ZNF263,EGLN3,LANCL1,CCAR2,SUMO2,MAP1LC3A,EED,RPL9,ATG7,CTNNB1,STK4,BAZ1B,PIK3R1,RPL6,WWP2,COIL,EEF1G,NUP50,EP300,FOS,PPARG,SOST,RPP21,AKIP1,PRDX3,H1-5,APEX1,RBBP4,FOXP3,ZMAT2,TRMT6,ZNHIT6,SCNM1,APEX2,HSP90AA1,COP1,SETD7,DCAF4,MYC,CUL3,PAPOLA,NEDD8,H3C1,KPNA2,FGF12,NOC4L,HNRNPK,TCOF1,TAF2,CBX3,SIX5,YIPF4,PPARA,ING1,TP53,RAP1A,MDM2,CWC15,MCL1,RB1,CDK6,LDLR,H2AZ1,RCHY1,UBE2N,RPS2,TOPBP1,CHCHD1,CSNK2A1,MFN1,GAPDH,SUV39H1,TLE1,MBD3,BCL6,HSPA5,FBXW7,HMGB1,SYVN1,DVL2,UGDH,PML,NBN,SIRT7,SUPT7L,ACACA,LMNA,CDK1,PICALM,WWP1,EIF2B3,FGF13,BRINP1,PIP5K1A,SFRP4,SMURF1,NDN,NR1H2,CSNK2B,ING2,SYT2,GTF2A1,HEY2,UBE2I,TBCCD1,CREB1,CTTN,STK11,ZBTB38,FBXO7,DNAJC8,KPNA6,AR,CDC16,AKT1,CCNB1,RPL7A |
| 1.006e-03 | -6.90 | negative regulation of neurogenesis | biological process | GO:0050768 | 132 | 56 | 18204 | 5365 |
MT3,CTNNB1,NKX6-2,IL6,ID4,CERS2,DLX1,TP53,BRINP1,TNF,PROX1,THY1,DRD3,DUSP10,GPR37L1,SEMA5A,CCL11,NOG,TRIM46,HDAC6,LDLR,SPP1,IL1B,CDK5,YWHAH,PPP3CA,WNT7A,LHX2,RGMA,NF2,RB1,FGF13,B2M,BMPR1A,MIR181C,NRP1,MECP2,PTEN,PAX6,MIR137,TRIM11,IFRD1,PTN,PSEN1,MIR146A,CTDSP1,DICER1,RNF10,F2,SYT4,CTNNA1,TNR,NR2E1,BTG2,TSPO,RTN4 |
| 1.010e-03 | -6.90 | synaptic membrane | cellular component | GO:0097060 | 400 | 145 | 19108 | 5553 |
KCND3,PCDH17,GABRA1,RIMS3,NPTN,LRRC4B,SLITRK1,LRFN3,DRD1,GABBR1,LRRTM3,P2RY1,DNM2,KCNH1,CNR1,KCNJ2,PRRT1,KCTD16,LPAR2,SRC,CNTN2,CRYAB,PICK1,GPHN,ZC4H2,SSPN,CHRM5,SIGMAR1,AP2M1,PSEN2,FLRT3,ADORA1,PSENEN,KCNJ11,PPFIA2,HSPA8,SLC6A2,LRRC4,STXBP1,TMUB1,KCNB1,NINJ1,DAG1,APH1A,ADORA3,RALA,CHRM1,SLC6A7,CHRM4,DLG4,HTR2A,GAD2,TRAPPC4,SLC6A3,SNAP25,GLRA1,RIMS4,PNOC,CTNNB1,ATP6AP2,ZDHHC17,LIN7B,FCHO2,EPHA4,GPM6A,GRIK1,CHRNA7,ATAD1,GABRB2,DLG1,SNTA1,GABRA2,RAP2A,CRKL,ATP2B4,SNAP91,GRM1,STX1A,P2RY4,GLRB,NSG1,RGS7BP,NETO2,KCND2,OPRK1,KCTD12,KCNA2,NTNG2,SEMA4C,CBLN1,NRP1,LHFPL4,CNTN1,LIN7C,SYP,PSEN1,CASK,TIAM1,HTR5A,KCNA3,NETO1,SYNDIG1,PICALM,ABHD6,CDH8,KCNC1,SLC6A6,IGSF21,PCDHB13,SLC6A11,PDLIM4,GRID1,NLGN1,CLSTN3,KCNMA1,NLGN2,SLC1A2,NCSTN,CPLX3,GRIA2,MTMR2,EFNB1,SLC6A4,CHRNB2,FXYD6,CACNG3,SLC4A8,GRIA1,DLG3,CHRM3,GABRG2,SLC6A1,LPAR1,STX11,KCNJ3,LRRTM2,GLRA2,LRRTM1,ABHD17A,EXOC3,GRM2,RNF10,PDE2A,KCNJ8,GABRB3 |
| 1.012e-03 | -6.90 | urinary_tract-bladder-carcinoma-adenocarcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-adenocarcinoma | 32 | 18 | 16828 | 4835 |
FBXW7,JAK2,PTPN11,AKT1,TP53,MET,KIT,CTNNB1,AKT2,TERT,CDK4,PIK3CA,FGFR1,HRAS,AKT3,KRAS,MAP2K1,GNAQ |
| 1.012e-03 | -6.90 | granulosa_cell_tumour | COSMIC cancer mutations | granulosa_cell_tumour | 32 | 18 | 16828 | 4835 |
PIK3CA,DICER1,PTEN,TP53,IKBKB,BRCA1,KIT,PPP2R1A,IDH2,NF2,CDKN2C,JAK2,STK11,SF3B1,KRAS,HRAS,IDH1,PIK3R1 |
| 1.012e-03 | -6.90 | fibrosarcoma | COSMIC cancer mutations | fibrosarcoma | 32 | 18 | 16828 | 4835 |
ETV6,CDKN2C,FBXW7,RB1,KIT,MET,CTNNB1,TP53,PTEN,TERT,PIK3CA,IDH1,HRAS,KRAS,EWSR1,SF3B1,STK11,SS18 |
| 1.012e-03 | -6.90 | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | COSMIC cancer mutations | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | 32 | 18 | 16828 | 4835 |
PPP2R1A,IDH2,NF2,CDKN2C,JAK2,TP53,IKBKB,BRCA1,KIT,DICER1,PTEN,PIK3CA,IDH1,PIK3R1,KRAS,HRAS,SF3B1,STK11 |
| 1.013e-03 | -6.90 | regulation of cellular component biogenesis | biological process | GO:0044087 | 1016 | 344 | 18204 | 5365 |
SYNDIG1,HSP90AA1,CSF2,SNAP25,GDI2,CDK5R1,WDR45,PSRC1,INPP5K,TMSB10,SFRP1,FERMT2,CRYAB,NUPR1,MIR142,LRRTM3,CDC42,G3BP1,FCHSD2,ADD2,FAM98A,CLDN1,MIR149,CBLN2,MTM1,CRB3,HSPA5,BRCA1,TACR1,MYD88,SWAP70,EFNA5,MSTN,CAV3,SEPTIN7,CNTROB,MEF2C,KCTD17,IFNB1,TRIM11,CPTP,CAV1,GPBAR1,MAVS,SSH3,ARPC2,TPPP,ISG15,CCR7,VPS4B,GREM1,C9orf72,PTPN22,WASL,TRIM37,DYRK1A,RAB1B,DKK1,SEC22B,ADD1,NCK1,MIR9-1,SVIP,MIR144,DUSP3,EFNB1,NAPA,CBLN1,BECN1,SNAI2,CNOT6,DLG1,MIR20A,GHRL,CCL21,SOX9,ABITRAM,CHGA,HGS,DRG1,RAP1B,SUMO1,CLRN1,IL5,TTC8,NCKAP1,TMOD2,CRBN,PTPN11,CCL11,CEP97,APLNR,TLR4,ARF4,RAC2,HSPA8,CYRIA,CHMP1B,SOST,CLEC7A,NEK7,VPS4A,LPAR1,SDC4,SDCBP,TP53,LCMT1,CHMP4C,SCFD1,PPARG,CLSTN3,CXCL13,CSNK1A1,PTGER4,CDKN1B,F11R,TMOD1,RAP2A,RHOG,CHMP5,MAPRE1,CCSAP,CAPG,FAF1,CHRNB2,LRFN3,ATAT1,TPBG,LGALS3,MKKS,GPM6A,IKBKB,S100A10,PREB,RNF5,TBC1D24,MIR98,EMILIN1,IL1RAP,TAPT1,STXBP6,LRRC24,PYCARD,HRAS,ZNF304,STUB1,ABHD17A,CORO1C,ORMDL3,HMGB1,STX1A,NTNG2,EPHA2,TRAF2,MIR145,SLAIN2,RAB11A,RPS3,LRRTM2,TNF,TBC1D1,HAUS2,ROCK2,CX3CL1,CAPZA1,RAF1,ANKRA2,PIP4K2C,ARF6,CLDN3,TBC1D16,MIEN1,TBC1D17,MIR214,MIR17,PRKCA,TPPP3,TBC1D5,LDB1,ASIC2,RB1,CTTN,ADNP,WDR44,LRRC4B,TBC1D10C,TBC1D13,USP16,ATG3,TMSB4X,SPHK2,SH3GLB1,TMEM39A,MIR105-1,TBC1D19,CLIP3,HAX1,MAP4,GPC4,DAPK3,SLX1A,FLOT1,HAS3,VPS33A,MORC2,USP6NL,SLITRK5,BAX,CHMP1A,PYDC2,GPM6B,LRRTM1,G3BP2,MMP14,LDB2,DNAJB6,MIR21,DNAJB2,ORMDL1,RGCC,METTL18,GPRASP3,CHMP2B,CDC42EP4,CD36,VPS18,ARPC3,MNS1,MAD2L2,TPPP2,CHMP2A,GPR65,WNT10B,SAR1B,TLR6,SMAD4,VPS39,FAM107A,WNT7A,TGFB3,IL1B,AKT1,NOP53,MAP1B,BAK1,CTNNB1,CYFIP2,OXTR,RALA,CCL24,VDAC2,CNOT2,EP300,SNX18,PAK2,MSN,LHFPL4,MET,LMO4,RPL13A,CDC42EP2,KIT,FLRT3,EIF2AK2,PRKCE,LCP1,PTEN,STXBP1,TSG101,NRP1,TIRAP,NR1H2,CAND1,COTL1,EPS8,STX18,THY1,NEGR1,DAG1,CALY,SRC,ROCK1,P2RY12,PIK3CA,CD47,CAMSAP2,NLGN1,IFNG,SPTAN1,ICAM1,TFIP11,NTRK2,STMN2,FLRT2,ACTR2,CTNNBIP1,PIK3R2,PIK3R1,AMIGO1,VEGFA,CAPZA2,NF2,TICAM1,SLITRK1,MECP2,MTPN,NUDT16,HDAC6,POLDIP2,MALSU1,STAP1,SETD5,CLU,SYK,ARFGEF1,RALB,RAP1A,SLITRK2,TMOD3,TRIM32,ESAM,BIRC2,TFRC,CNOT6L,SPTBN1,DUSP22,SMAD3,CCL19,LRRN1,LRTM2,FEZ1,CDC42EP3,CYRIB,XRCC5,FKBP4,TLR2,NLGN2,RAB5A,VPS16,UBLCP1,TESK1,HCLS1,PHF23,NUP62 |
| 1.013e-03 | -6.89 | Interleukin-1 signaling | REACTOME pathways | R-HSA-446652 | 46 | 25 | 10285 | 3229 |
MAP2K1,IL1B,TOLLIP,IL1R2,UBB,PELI3,SQSTM1,PELI1,UBA52,IL1RAP,RPS27A,TRAF6,SKP1,IKBKB,MYD88,MAP3K3,UBE2V1,NFKB1,IRAK4,FBXW11,IL1A,MAP2K6,TAB2,UBE2N,TAB1 |
| 1.014e-03 | -6.89 | CST1 (cystatin SN) | protein interactions | 1469 | 141 | 57 | 19454 | 5460 |
CSNK2B,CHAC2,SGTA,SCAMP2,TECR,UQCRQ,PARL,RNF141,APEX1,B3GALNT1,HMGCS1,TIMP1,DNAJC8,STK11,PFDN6,MDH1,TADA3,SPCS2,GPX4,C1D,TCEA1,RPA3,SLC32A1,GREM2,ATAT1,FTH1,CD59,TIMM10,FBXO42,ADSS2,HBM,FKBP14,NXT1,CORO1C,TYMS,TES,GTF2B,COX4I1,MAP2K6,UBTD2,SPPL3,NKAP,TAX1BP3,GSTM3,DNAJC7,RING1,HINT2,ACTR1B,FKBP2,CTNND1,VDAC1,PPIF,ITGB5,RHOBTB1,BIRC5,TFRC,ACTR2 |
| 1.014e-03 | -6.89 | negative regulation of amyloid-beta formation | biological process | GO:1902430 | 29 | 17 | 18204 | 5365 |
MIR153-1,CHRNA7,MIR361,MIR29A,NTRK2,ROCK1,PRNP,MIR455,MIR24-1,MIR298,MIR339,SPON1,RTN4,MIR29C,MIR186,IGF1,CLU |
| 1.014e-03 | -6.89 | negative regulation of leukocyte cell-cell adhesion | biological process | GO:1903038 | 149 | 62 | 18204 | 5365 |
PELI1,PPARA,ADTRP,PRNP,BTN2A2,KLF4,FGL2,HFE,FOXP3,CD274,AKT1,CXCL12,BCL6,LILRB1,HMGB1,PRDX2,PTPN22,CD86,IDO1,DUSP3,XCL1,DUSP22,IL10,TWSG1,VSIR,SDC4,PDCD1LG2,MIR21,IFNA2,MIR30B,LILRB4,DLG1,CTLA4,MIR146A,IL2,SFTPD,MIR221,CCL25,TNFAIP8L2,IRF1,GPNMB,NDFIP1,MIR31,MIR222,IL20RB,SOCS5,CCL21,RUNX1,ARG2,MIRLET7G,MIR141,CBFB,CD80,MIR181C,MIR125A,RC3H2,CCL28,PLA2G5,TNFRSF14,IL2RA,LGALS3,IFNB1 |
| 1.015e-03 | -6.89 | CLIP2 (CAP-Gly domain containing linker protein 2) | protein interactions | 7461 | 23 | 14 | 19454 | 5460 |
TUBB4B,MAPRE1,TP53,RAF1,MAX,BORCS6,MSX2,GTF3C4,DYNLL1,VRK1,PRNP,VIRMA,APEX1,COMT |
| 1.015e-03 | -6.89 | GNG4 (G protein subunit gamma 4) | protein interactions | 2786 | 23 | 14 | 19454 | 5460 |
GNB3,GNA11,HNRNPL,KCTD17,GNB4,GNB1,GNAI2,RAF1,CD81,DHRS3,TFIP11,PDCL,GNAI3,GNAQ |
| 1.015e-03 | -6.89 | PECR (peroxisomal trans-2-enoyl-CoA reductase) | protein interactions | 55825 | 23 | 14 | 19454 | 5460 |
TP53,HENMT1,RAF1,FNDC11,UBE2E3,CPE,TRIB1,RNF181,GRAP2,ACTA2,CDPF1,LCN1,RAP2A,HNRNPF |
| 1.015e-03 | -6.89 | TOMM7 (translocase of outer mitochondrial membrane 7) | protein interactions | 54543 | 23 | 14 | 19454 | 5460 |
SFXN2,ACAT1,SDHB,SFXN1,TOMM20,TOMM70,TOMM6,TOMM40L,TOMM40,TOMM22,NDUFB7,BAK1,FAM3C,CISD1 |
| 1.015e-03 | -6.89 | UBOX5 (U-box domain containing 5) | protein interactions | 22888 | 23 | 14 | 19454 | 5460 |
UBE2L3,UBE2K,UBE2D3,UBE2H,UBE2D1,UBE2E3,TRAF6,TRIM23,UBE2V1,EMILIN1,UBE2E2,CUL3,USP2,UBE2W |
| 1.015e-03 | -6.89 | endometrium | COSMIC cancer mutations | endometrium | 15692 | 4554 | 16828 | 4835 |
STX17,LEPR,WNT7A,CXCL1,XPOT,FRA10AC1,PDIA3,NAA11,NDUFB8,ISYNA1,KRR1,NLE1,SNAI3,CDC37L1,PELI3,MSX2,RPL37A,SERPINH1,SIPA1L1,STAMBPL1,PGBD2,HSPE1,ZKSCAN1,CLDN14,KCNA2,B4GALT6,LHFPL1,NUDT16,OR6M1,GXYLT1,DHX16,TRA2B,RAB4A,SOX21,HADHA,LEAP2,TAC1,OPA3,NPVF,IGFBP4,LMBR1L,AKR1C2,IPP,NQO1,SPATA2L,TBCE,CD3G,BRMS1,PAOX,CDKL2,KIF1C,GAS8,CHRNA7,HEXA,ADAT1,OCEL1,BRI3,RBM23,TMED1,OXNAD1,CCL21,NDUFA5,KCND2,NEDD8,CXCR1,HBB,FGF17,TRMT6,PTCRA,TIGD7,FBXO30,POLR2I,CD2,RAP1A,UCKL1,ACAA2,RABAC1,WWP2,IL34,ST13,LPXN,RASGRP2,PRCC,GSK3A,PCDHA5,SLC20A2,NUBP2,LDHA,UBXN10,RC3H2,ATP2C1,FATE1,THOC1,ABCC5,RANGRF,NUDT19,TF,RNF103,CREB3,XPO5,SURF4,INTS10,EXOC2,XPO1,THRAP3,EEF2,SLC25A32,EFHC1,GJA10,SLC7A4,ZNF513,TXNRD3,ZMYND11,APOBEC3C,GPR162,RNF187,ENDOD1,ANKIB1,CIRBP,CXXC5,OSR2,GALE,EIF2B5,SH3GLB2,WBP2,GTF2A1,FUT8,SPOCK1,LASP1,PHKG1,MOB3C,UTS2R,NEK7,GLE1,CCL25,GNMT,AQP4,TXNIP,CREBL2,SLC39A9,FURIN,DHX9,IL23A,PSMD6,EIF4EBP3,WDR37,ZSCAN1,OR51S1,STX8,BATF,TOLLIP,TGFB1I1,DUSP1,NFYA,FAM200A,S100A10,CACYBP,CTSK,CETN3,URM1,PWP2,MTAP,RAB3C,DCAF8L2,NDNF,AP1G2,CHST9,CPT2,ANP32B,COX7A1,FBXO9,CCND1,RPGRIP1L,OR2W1,ACOT13,TMED3,SETD4,OTUD6B,LCN6,SPINK13,RHCG,SCG2,ARHGAP21,FAF2,BMPR1A,KLF10,MPHOSPH10,MRPL47,TMEM33,S100PBP,BACH1,MIA2,KIF2A,INPPL1,CRYBA2,DEGS1,ID1,PTDSS1,ARMC8,ENTPD4,SLC35A2,FCAR,NPTN,CCDC42,CYC1,POU1F1,PPIB,BPGM,PRKD3,CYP4F8,SLC5A6,DEK,NLGN2,SCAMP2,OR52M1,NUP107,SPEF1,FABP5,MRGPRX4,PGAP2,CTSD,RBCK1,MRPS25,SPATS2L,NOP58,AKR1A1,NFE2L1,MTMR12,DUOXA2,TRAF7,MMACHC,TNFAIP3,ZBTB42,ABHD16B,RRAGA,ETV6,TAPBPL,FYTTD1,IQSEC1,NOL4,SIRT7,POLL,NONO,ALDH1L1,MAK16,TSSC4,SPRED1,SNAPC1,SNTA1,GPR37L1,NDUFAF2,SIVA1,GFOD1,OR2A2,EIF4EBP2,TCP11L1,SOST,ZNF805,HPCA,SV2B,ENPEP,NAB1,VPS4A,FGF13,PRKX,PROX1,SYNGR1,LSM6,RTP4,USP38,ZNF174,SLPI,CERK,USP39,ADCY3,FAM13B,SNRPD2,CDK6,CWF19L1,ESR2,DCAF5,CYP2D6,INTS12,SOCS2,RAB8B,CTNNB1,OAZ2,CLEC12B,SFTPD,TRIM23,NAIF1,NHP2,P2RY1,ING1,STRBP,IRF1,OR8B8,UBE2D3,CCT2,CHRM4,UBE2A,ARMCX1,PRPSAP1,GRPEL1,ELMO1,TCP11L2,FGFR1OP2,GABARAP,OR4D11,GAL3ST1,CASK,LTBR,LMO4,CLU,ATPAF2,KIAA0232,NRP1,NCKAP1,CDK5R1,GLUL,CNIH4,XAGE5,SEC14L1,ZNF319,ZNF397,APOBEC3A,CCR6,ZMYND19,SLAMF9,TAAR1,ADGB,JAKMIP1,GPAA1,TLR3,IDH3B,GALNT4,GRM2,CTNNBL1,CYP11B1,SENP5,GNRH2,CHDH,FAM8A1,EIF4H,ITK,MYL12A,CYP39A1,HSD11B1,SWAP70,LRRC69,SNAPIN,KLK3,SLC30A5,MRPL24,MRPL50,ZNF304,MEF2A,IMMP2L,SLC35A1,HSBP1,DHRS4,ENY2,RAG1,FAM78A,PPP1R2,MIOS,RMND1,SLC38A9,OSM,IL15RA,MRPL13,MDM2,MGP,EHBP1,AK2,SOCS5,GALNT1,CCDC69,PSMA3,TMEM156,GSTO1,NUDT3,B9D1,RND3,CNP,TOM1L2,UST,EXOC8,PFDN5,LYAR,CDO1,ASMT,CCNI,RAB11A,PPIL4,IL20RB,DKK3,SF3B4,RPS23,DPP10,PRRC2A,CRABP2,FGD2,APEH,AKT1,DLX1,FNDC8,TLR9,FIBIN,WDR38,SNX20,L1CAM,TMUB1,C1QC,TRIM3,POLR3H,ZNF207,ATP6V0B,LYPLA1,LIG3,UGCG,MEAF6,SLC17A5,SLC25A31,ZNF671,TRIM32,UBR7,PDIA6,SDR42E1,PRIM2,SNRNP27,CD99L2,DOK4,ARHGAP1,KLK9,PLA2G5,KLHDC8B,RNF141,GFM2,MRPL23,GDI2,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,E2F6,GHITM,RPL15,TUBG1,CACNB4,CCDC47,SCFD1,TTC4,BUD31,TMX4,SRP54,CAMK2G,PRMT2,TACR3,CIB3,CD200R1,CRYGB,PPP3CA,KCNJ11,RCVRN,PEX3,CCDC127,PYGM,OR4K1,SHC1,FGFR1,SMCP,FBXO32,ANAPC2,AGK,SBK2,SORD,SLC39A7,ENPP4,CCT5,PSMB5,MCOLN1,FKBP14,IDH2,RAB18,IMPACT,AGER,CD58,PRPF4,ZNF593,ARMCX5,SLC25A21,RBBP7,PGS1,RMND5B,PTPN1,SETD5,HNRNPC,NFIL3,HECW1,TRIM37,ZBTB38,GALNT12,ARFIP1,PPARG,SPR,ARMCX2,SIX5,TRIM21,ACTA2,RBM17,PCDHB8,HEY2,RFX4,FRMD8,PKNOX1,ADRB1,ZDHHC14,LRP12,NPY2R,SPTAN1,SLC35E3,RNASET2,TRAPPC1,FAM199X,CLDN11,NIPA2,PAEP,RABL2B,ZCCHC10,SYN3,MX2,GPBP1L1,TMEM213,AAMP,LYG2,MFSD6L,ATP6V1G1,MEST,FZD4,WDR77,MTPN,SERPINB10,TSEN54,ZNF24,TMEM215,FBXO42,LBH,JAK1,MAGOH,TBC1D10C,GTF2E2,PSME2,AZIN1,AZGP1,INO80C,ABCB1,HBE1,KTI12,RAB3B,CDCA3,SMAP2,DEFB116,TNFAIP8L2,DHRS3,DNAL1,NDST1,GSTO2,KBTBD2,GNG7,ATF4,CSNK2A1,PIWIL4,KPNA1,RARRES2,GRSF1,LSM3,AFTPH,OR4D9,KIT,RS1,P4HA2,JOSD1,SUPT7L,BTF3,MMP9,CDC73,UBAP1,ZYX,LHX2,DYNC1I2,CYP27A1,TMIGD1,DNAJC5,PGK1,ROPN1B,VRK1,MYH2,SNAP91,PACSIN3,SLC7A9,ALKBH4,HEBP1,LMNB1,BECN1,TES,CCDC25,CALHM2,GMPPB,HSPA8,MSMP,SLC19A2,CBR4,VMP1,CHMP2A,OSTM1,EMP3,TMEM204,PROS1,GPX3,EWSR1,ZNF592,MTRF1,YAF2,ELP3,CIB2,TRIM24,ACSL4,MRFAP1L1,TGFB3,DTYMK,ABHD14B,EED,CD274,EIF3K,B3GALNT1,CREB3L4,BCAP29,ZBTB17,FABP7,RINT1,TSPAN5,OR10G9,BZW2,SPECC1L,NAT2,CALHM3,LHFPL4,CDKN2C,COX4I2,EIF4E,TRIM5,SSU72,AKAP12,IGBP1,RAB40AL,DDX39A,SNAPC3,SNCG,BLOC1S2,TFE3,MT1M,DEFB114,IFNA10,PELP1,ITGA6,CSNK1A1,COMMD8,TSPO2,OLFML3,GOLGA7B,EFNB1,RNF113A,SH3GLB1,PREPL,THTPA,UBE2V2,IL10,RPLP0,NTN4,RTKN,ADIG,HOXD12,PHYH,FUT9,ST3GAL1,SOX2,CSNK1A1L,DERL1,IL18,UQCRH,DPEP1,PRKAB1,ERV3-1,PCMTD2,STOX2,KLC2,PAX9,STXBP1,MTHFD2L,CD36,IRF3,PYROXD2,MRPS21,LRP6,TAS2R40,RAC2,STK24,LCA5,ST3GAL5,POR,CEP97,ZNF501,IFRD2,PARP11,SLC32A1,NME1,DUSP19,RGS2,STMN2,MBD5,KCNMA1,NOS1AP,BCL10,ADPRH,PDHA1,KCNK13,TRAF2,RBM7,BRCA1,PCDHB1,ABHD4,NR1I2,CNNM4,DPY30,CDK4,NPR2,STOML3,TSN,STAU1,SLC41A3,SERINC3,TMED7,RNASEH1,DNAJC3,FKTN,KLK6,PRPF19,CREBBP,LDOC1,GPAM,PDCD4,RDH10,HTR1F,OR4Q3,POPDC2,GPX6,TGIF2,GREM2,RPLP2,FAM98A,ACBD7,TRIM54,TMEM114,ACAT1,TMEM184B,KDM4B,ZNF287,RAB3D,CLDN4,SLC13A5,LAMB2,NKIRAS1,OAS1,GIT2,RUVBL1,SDF2L1,GTF2B,CXCL3,SAT1,R3HCC1,CSGALNACT1,SMU1,SLC35D1,COL1A2,RMI2,PTS,TOR2A,AMIGO1,JPH4,GTF2H2,MBL2,MAP3K11,GNG2,EDEM1,VAMP5,METTL14,LCP2,CRTAP,UHMK1,ANKRA2,ADIPOQ,ALKBH5,ERH,CRYBB2,AKAP14,NDUFAF4,CCNB1,CTDSP1,FAM162A,METTL2A,ABHD6,CLDN1,TFCP2,CDKN2AIP,RGS7BP,SFRP4,RER1,FCN2,FUNDC2,MRPS23,ZNF862,ATG4A,SYP,CSRNP1,POLE4,HSP90AB1,ISG20L2,TMSB10,IPO8,ATAT1,CIDEB,TMEM123,AIF1L,CCR2,ZC3H7A,ZBTB5,DSTYK,NRSN2,TMEM144,TOP1,SRRM5,BCS1L,SNX17,APOO,GPR137,CYP2C18,NDUFS8,ZNF740,MYO6,OPRK1,GCNT3,F9,NKX3-1,TOM1,BCL7B,SEC61B,TEX30,GPR65,PAPSS2,TCF23,CHGA,GBE1,EIF2B3,DNAJC22,HTR5A,TMX3,HIRA,S100A8,CD47,TMEM50B,IFNG,JUN,WWP1,RHOJ,CBLN4,SFT2D2,CMAS,RAB23,CCR3,OGG1,ZNF687,OPHN1,SUMO3,FAM107A,RNF167,RAB33A,CRYGD,DNAJC8,PPDPF,TNFSF18,CHI3L1,RNASEL,TOMM40L,EIF3J,FERMT2,GIMAP2,GNPNAT1,UTP23,TNRC6C,SPTBN1,ACAP2,MAFG,SCD5,LHFPL2,HNRNPK,PRKAG1,NFKB1,POMP,OS9,MRPS28,RIOK2,OAT,CLDN22,EGLN3,FOS,DYRK2,YPEL5,PPID,NAA60,CCL8,TPPP,RFTN2,SLC35E1,RB1CC1,CAPZA2,MAPK1IP1L,FANCG,OR2A25,STX6,PLA2G15,RCBTB1,GGCT,ATP6V1C1,TAPBP,HNRNPA2B1,TMEM177,FMO2,RAN,RBM12,SQSTM1,GLIPR1,NAPG,RNF122,KIAA0408,BICD2,SERPINA5,KIAA1191,CCL17,OR2H2,DLG4,GTF2F2,KCNH1,POLR3B,HAND2,PGR,LCN9,BRD9,HSPA14,CXCR4,NPY5R,MT2A,PPP1R16A,ATP1A2,GMPPA,CYB561D2,SLC7A14,DDX42,BNIP3L,TUSC3,RPL6,CLDN8,ADAMTS1,CXCL14,KLHL15,TRAM1L1,SESN2,PAPOLB,PLAGL1,RFXANK,FCHO2,CHST1,MPV17,EHD1,PPP1CB,TRAM2,GCA,RABL3,UPF3B,ZNF576,KRT7,PLEKHA8,GJB2,WDR3,MANSC1,NUS1,SRP14,TMEM106C,SLCO1A2,KCNK10,SELENOS,TMCC2,ZNF609,ACP6,SYNJ2BP,TMEM164,ACTR2,OR4F6,CRYBB3,PTRH2,FOXS1,TAS2R5,GYS1,SLC23A2,ROGDI,PGM2L1,PIWIL2,SOS2,AKIP1,SDHAF2,CLIC2,OTUD7B,PPFIA3,FOXN2,RBFOX2,GK2,CDKN1A,SLITRK2,STX18,ELSPBP1,ORAI3,HMBS,TDRD7,CD2BP2,CCDC65,LDHAL6B,AMY2B,NDE1,RBMX2,RPAP2,INHA,RGS5,OR5L1,RAB1B,HRH3,ABHD13,ZBTB45,LY6G5C,SLC4A8,SNIP1,FAM168A,ACTL6B,B3GNT2,HIGD2A,TEX12,TOP3B,ZCCHC9,SLC43A2,TMEM91,DDX4,LIX1,KLK5,GRIA2,LRRC24,FLYWCH2,MRGPRX2,OR14J1,CDH8,CPSF2,TMEM14A,GDE1,TCEAL7,PCGF3,GPX5,TRIQK,MOV10,NGB,GLT8D1,UQCR11,PNPLA8,MYEF2,TAF5L,PDYN,ZFP1,B4GALT3,CD226,VPS33A,SACM1L,CRBN,TRAPPC6B,CCNF,CTNNA1,RAB2A,GPIHBP1,WDR44,BEND5,CMPK1,SNRPA,OR10G7,ISG15,ACADSB,SNX24,STAT6,PHYHIP,WIF1,FN3KRP,DYRK1B,AMT,RAB9B,EZH2,ARCN1,FGFBP2,INPP4A,KCNIP3,RPL23A,LYNX1,TMEM59,IL6ST,TIMP1,TXNL1,DERL2,ELMOD1,MLF2,PLEKHJ1,PPP2R1A,PTHLH,MRTO4,SLC25A4,SMAD3,EIF4B,RAB5C,PNP,PCDH19,WEE2,AP1AR,TIMM10,SELENOK,STK38,CSTF2T,PSRC1,IFI35,FBXO25,C1QL1,CAV2,FOLR1,SLC6A11,RAB37,OR2Y1,STX11,PMP22,SERPINA1,LARP4B,HSPA13,LSM10,ANKRD34B,SH2D1A,SLC11A2,UBB,PPP2R5E,LMAN1,NPSR1,MRPL11,SCLT1,LRRTM3,DAAM1,RPS7,PSMD4,NPPC,RELL2,TRIM15,RAB27A,GRAP2,RHEB,FBXL14,OVOL1,DHX15,OCRL,MAT2B,MLC1,ZNF664,DDX46,PDHB,TSPAN18,RPS6KA4,GANAB,BBS5,XCL1,SLC6A6,CCDC134,SLC30A7,KCNJ3,B3GALT1,COMMD6,TMEM30A,AFAP1L2,GNPDA1,IMP3,IRAK4,UBL3,GNAO1,CYP21A2,NCDN,TMEM117,TMEM170B,NDUFB6,MRPL34,SFXN2,SNX22,CST11,FASTKD5,SAV1,TAGLN3,STAT2,PCDH17,EPCAM,SRSF7,IL22,TOR3A,GLRX,UBA3,CBLL1,TMEM179B,TOMM22,BFAR,CSGALNACT2,RPL7L1,HENMT1,CSTF3,REEP3,ST6GAL1,TOM1L1,KDELR1,KRAS,RPS16,RRM1,RBM22,ORC5,ILF2,OXSR1,BAG3,ZNF365,PSMB1,ZMYM3,ASNSD1,CNTN2,HERC4,DKK1,NR2F6,CHPF2,CFC1,CCS,RASD1,SCGB1D1,NLRP3,ILDR1,COMMD3,BMPR2,RND2,PPP1R1B,OLFM3,SCG3,FGFBP1,MFSD5,MRPL18,METTL21A,G3BP1,CHAC2,POP5,PSORS1C2,RPS27A,PCDHB13,TPD52,DBT,RAPGEF5,ELOVL7,DAPK3,DSTN,NUF2,OR13C8,HINT2,TMEM101,SLC16A1,CHCHD4,CHIC2,MRGPRX3,CCDC86,MTA2,SUFU,LAPTM4A,FBXL19,KCNC1,OXTR,PGGT1B,SLC38A7,SMG9,MUL1,MAPRE1,NRN1,SEC22C,ZFAND2A,MME,METAP2,TWIST2,APOBEC3G,GNG12,PABPC1,NTRK2,FKRP,LPAR2,USP15,OR10A4,ELMOD2,CNRIP1,GNAZ,RTN4,ISX,GAMT,TOMM6,SIAE,RNF144B,DNAJB9,ARG2,ADAM21,PTAR1,MGAT5B,UAP1,THAP7,INO80E,DEPDC1B,RLIM,PTEN,CRLF3,CENPW,SDHB,GFPT1,ATG4C,SNRNP48,FRRS1,TXNDC12,RWDD3,EPHX1,ABHD5,CXCL13,SIT1,FDFT1,NEGR1,MOXD1,RPA3,CCDC160,FBXW11,CINP,CNDP2,PPFIA2,OR4D6,THBD,BCL7C,TYW5,RPL27A,CBLN2,NUDT12,HTRA2,SNAP29,JAGN1,NDUFAB1,DHX38,GPR171,PTK7,USP8,TMEM147,LGALS8,COX8A,METTL15,BABAM1,NEUROD2,PGRMC1,CHST2,RHOBTB1,FZD3,CD247,IKZF5,NXT2,TMEM126B,NDUFS6,CTSC,SPRED2,CDAN1,OPRM1,PDE1B,UBE2K,PIK3R2,PCNA,DDX23,PCYOX1L,CREG2,AGPAT5,PLD3,LRRC3,HR,DNTTIP1,FBXO44,ARPC3,DKC1,UBL5,BTN2A2,CSH1,IFNB1,CCNH,SEMG2,KIAA0513,MNS1,POLB,POLA2,UBASH3B,TOR1B,KANSL3,SPSB3,ABCG2,LTA,MRPS9,FAM83C,UGT1A1,MTF1,PTH2,MSTN,RPL27,PPP1R1A,PRICKLE2,RNF148,CLDN9,DIO1,SLC16A10,VGLL2,SLC35F2,TRMT112,SYNCRIP,ZNF821,DDX50,CTXN2,HINT3,VRTN,SLC25A10,RPRD1A,GTF2H5,SPON1,STK4,BST2,PPP2R2C,CYP1A1,ST8SIA5,PLS3,SLC22A17,TNKS,TMEM41A,IL1R2,ACVR1C,NKIRAS2,RBM38,STUB1,PIP4K2C,KLF9,ST7,AVPR1B,GSTA1,UBLCP1,SERPINB1,TRAK2,TEX264,SNRK,POLR2B,TSNAX,GTDC1,UBIAD1,LRRC61,DHRS13,PARL,UBE2W,FBXO22,REG1B,GPM6B,SLC7A8,RFC3,ATP6V1A,ACP5,SERPINC1,TMEM59L,COPS7B,DENND2D,KLF4,OR4D2,OR10A6,ACBD6,PREB,NFKBIA,ATG7,TAF10,FAM53B,PRDX1,TRIM68,ETF1,LRRC8B,USP16,TCEAL1,PFDN2,HARBI1,TMED5,HMGCS1,SLC25A12,AK3,CLCN6,RPL32,DDRGK1,DRGX,SHOC2,SMPD2,NCBP2,TBC1D13,SOD1,ATXN10,ASTN1,DTWD1,REN,CCR1,VEGFA,FAF1,DECR2,AVL9,IQCK,TP53INP1,NAPA,NOTCH2,SOBP,PTPN11,TM4SF19,CRAT,TMOD2,GNPDA2,THOC2,STARD4,NR2E1,DROSHA,FLOT1,ORC6,SCNM1,MCM4,FAM177A1,DCTD,SLCO2B1,CX3CR1,FAM219A,IGF1R,CHMP4C,CEP19,SOX14,PDAP1,KLHL22,UBP1,MAVS,CD1C,UMPS,RAB19,CDCA7L,SS18,MRPL22,HOXC4,UPK1A,EPS8,RFXAP,CER1,POLR1B,SIAH2,CHCHD6,NUDT7,IFIH1,BIRC2,MTM1,VGLL4,SCML2,FCGR1A,CCNY,CHKB,PKP4,GPR176,CLD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SP14,CHMP5,ASB3,ZMYM4,EIF2S2,TMEM176A,ANAPC13,CNTNAP1,RNF39,PBLD,HDAC6,EYA3,DUSP26,ACTL9,OTUD6A,STOML2,NUP153,TOR1AIP2,MICB,RNF20,COPS7A,PPARA,GPR15,FRS3,RPL35,POLR3F,RERG,ATL1,SNCB,TPT1,RRAS2,STXBP6,LILRA1,DAPK1,PDE1A,KCNQ5,TPBG,SLC25A17,NFYB,ARRDC3,ZCCHC12,LRWD1,EEF1G,CDSN,SESN3,TESC,THY1,YWHAB,PSMD14,SLC25A44,ZNF692,ST6GALNAC3,TBC1D24,EDNRA,PRPF31,BMP1,NR1H2,MMADHC,TTC1,PHB2,SPOPL,SYT2,TMEM95,LEPROTL1,ZFAND2B,DNAJB6,DNAJC27,GCC1,LRRN1,CD1B,KDSR,ATP1A1,CRKL,TGIF2LX,PSMA5,AOX1,STARD13,B4GALT1,NLRP1,CNPPD1,STX12,CENPP,RP2,TMEM199,GZMK,FBP1,TXNRD1,TMOD1,KATNAL1,NAE1,GSTK1,GTPBP1,KCNMB2,RPS11,NUDT5,NDUFA12,DNAJC25,AZI2,EGFL8,ARL15,ILVBL,TM9SF1,SVOP,COMMD2,MAGOHB,PEX5L,MYCT1,ARL10,CBX5,FAM118B,CD46,GABARAPL1,KCNMB1,TRMT1L,CDC123,UCK1,GNAI2,PROM1,VMO1,MRPS18A,C1QL3,TRIM11,GLRA1,G2E3,MTG1,RPL3,QPCTL,TOPBP1,RBM18,RHOB,TMUB2,OR4K17,MAX,HOXB1,NRSN1,CSNK2B,YIPF4,FLRT2,CDC42EP2,PPM1G,DEDD,BOLA3,PLN,CD1D,MRPL52,FCF1,MYD88,E2F4,TMEM209,GLYAT,GFI1,IL1B,GPR26,SYS1,FUT1,PLAA,BAP1,LRRC4,MEF2C,DRAP1,ARFGAP3,ARL4A,LITAF,TP53INP2,SNRPD3,ZNF175,LAMTOR3,SEC61A2,RPS27L,ELAVL4,TNNT2,GOLPH3L,TESK2,COMT,STK11,RHCE,LY6G6C,ANGPTL2,TMEM106A,EXOC1,GPX4,RIMKLA,SEC62,FGF12,BAALC,PHAX,FKBP10,RPS5,CCHCR1,SLC22A12,SNAPC2,CYTH1,CCDC71,SLC1A1,PDE9A,TPSG1,UBN1,CYP17A1,FOXP2,UBE2F,LAMTOR1,ADNP,RAP2C,EIF4A3,DDX5,GTF3C3,RNF14,ZNF330,DET1,OR51A4,KLHL7,MCHR2,IRF6,RAF1,DNAJC10,RGMA,SAT2,PRRG1,GPNMB,PHKA1,MBLAC2,ALG2,RPL10L,COG1,SCYL2,KLF3,CCR4,SUMO2,TFB1M,LZTFL1,SNRPB2,IL17F,PPAT,CYGB,NUDT9,GGH,BANF1,ABHD12,NF2,PARP2,FOXA3,KLHL1,CARTPT,SESTD1,CGGBP1,RPL26L1,PHF13,PRKRA,TSPAN17,GNRH1,WDSUB1,ZNF451,PRKCE,TMEM170A,RNF133,COX6B2,TAS2R13,DBR1,FSTL1,POLDIP3,RHOBTB3,HGS,UBE2E2,CD81,CRISP1,DPH3,ELK3,LRRC40,NBN,VMAC,TNFAIP8L1,SEC13,IL2,FHOD3,SLC35B3,WDR11,NHEJ1,TYROBP,PEX13,AIPL1,ADTRP,SNRPG,TIMP4,XRCC5,ACCS,CDC20,WDR5B,ZDHHC4,DUSP21,TRIM45,ATAD1,MRPS34,CYP2C9,IGSF11,SGMS1,MGAT4A,RBBP8,NDST3,FBXO8,OLR1,SLC19A3,CDC7,PRL,MPPED2,BCL6,SYNPR,SSX2IP,GTF2F1,DLST,TMED9,GSTCD,PET117,USP6NL,MTDH,SGTA,SNX10,CA2,TPPP3,ZNF263,TMEM89,GABRA1,PRNP,HSD17B10,CAND1,MIS12,GTPBP8,HS2ST1,DR1,CBX3,ASPA,TRPC1,ELMO2,LYPD6,TSPAN15,TMEM38B,NPM3,CRTC2,GSTM4,ATP1A3,GH1,BAX,PEBP4,PSD2,NUDT2,COCH,FEM1C,VTA1,RPIA,PIK3AP1,XAF1,PICALM,COX6C,ANKMY2,RBM27,ZBTB39,CPT1B,CNN3,AKR1B1,TAB1,SF3B1,ADORA3,APEX2,AP1S2,LY96,MAD2L1BP,TMEM47,NDUFS2,TMEM185A,JAKMIP2,PSMC3,CDH11,PIK3CA,IVNS1ABP,FAM83B,SNRNP40,CPLX3,TNNI3K,GCLC,PSMD10,NPY1R,ARL4D,TXNDC17,LIAS,CITED1,KCNJ2,GXYLT2,EPHA4,FBXW7,TNFAIP6,PSMB7,DLK2,CDK12,DMTF1,PLG,TSR2,CHRM3,FAM149B1,FRZB,SPP1,ING2,ARL2BP,ZNHIT6,PRSS23,PLCB1,GPC1,GPR17,BOK,TM4SF18,OR6X1,TNR,ABHD8,ICAM2,YWHAZ,STARD3NL,OST4,CAPN2,LSM14A,SLC8A1,OR8H3,TM4SF20,CCNA2,AASDHPPT,SURF2,SLC29A1,MAGED2,GJA1,SPATA2,ADORA1,SLCO3A1,SHPRH,KCNJ10,TAF1D,PCGF6,GRM1,OR4K2,CXCR3,MAGEB10,HOMER3,HNRNPF,STAMBP,SLC25A1,FAM81A,ZNF511,CEND1,EHD4,ICOS,TRIM34,TMEM205,NDUFC2,RGL2,ITGB5,RPS2,LXN,TCEAL8,YIPF3,B4GALT4,CAV1,PDE4B,SPEM1,CYP3A43,MEPCE,EIF3G,TTPAL,UBE2L3,CCIN,FTSJ1,CNTROB,SREK1IP1,PRND,CPLX2,ABHD10,HUWE1,MRPS11,RAB39B,CSNK1G3,AKR1C1,PTP4A3,PLSCR1,DCAF12L2,LY6H,LILRA2,TNKS2,CBLN1,STK3,COMMD9,HSPB2,PROK1,JAK2,TRIM36,MRPS18C,NT5DC1,CREBZF,PAQR3,ALG11,HFE,DDAH1,GPR35,NDUFA1,HCAR1,TMEM127,GSTA2,FAM53C,MCL1,PNMA3,DPH5,CORO6,OIP5,TRIM29,RB1,CTXN3,ZBED1,PARD6A,TCEA2,LRRC28,PNPLA4,PIAS1,TMEM115,NPC2,HSPD1,EIF1AX,DDR1,SLC22A6,TIA1,SPG21,CAP2,SAP18,EXOC3,TMEM81,GLOD4,PIGA,MX1,BOLL,THOC3,S100A11,ZNF622,ATG9A,RBMS2,TGFB2,SLC25A27,VPS54,GRPR,IGFBP3,OR1M1,CD9,RUSC2,BTG3,TMEM183A,DPEP3,NUFIP2,CMC1,HINFP,GNB3,TMEM229B,ITGB8,CCDC3,VAV2,PAIP2B,LRP10,NR1I3,TRIM44,GPRASP2,PQBP1,PPWD1,FHL3,FAM20B,TICAM2,HSPA5,SERTAD2,GNA11,NRM,MPV17L2,CRYBA1,WDR45,THAP8,PDCL,SUPT5H,STAR,TRIP4,RPL10,GK5,GLCE,SLC25A24,SPINK9,PTGFR,IL2RB,IP6K1,CD209,TAS2R7,ST3GAL2,P2RY4,FBXW4,RAP2A,MSH6,MDFI,OR4D5,TEX261,ZDHHC16,OR51E2,GP9,KRTAP8-1,POLE3,FAM133B,RNF10,PSMD3,DTWD2,GPR160,POLR1D,CYP4V2,APLNR,CNPY3,NCAPG2,SRI,CTTNBP2,RAB6A,RGN,CDK7,SIN3A,PSMD7,SCAND1,PLAC1,PYCR2,TNFSF8,CDIPT,PDE2A,ZNF428,TLR8,PMPCA,NOG,MED22,ARFGEF1,CRY1,SLC6A2,TNFSF15,AIP,CD40,RPA2,TMEM107,PRSS8,LDB2,YPEL4,GADD45G,RNASE9,SRPK2,TAB2,TRAF3IP3,PIWIL1,CCDC90B,RGP1,EID2B,PRCP,CD34,FBXL4,UNC79,THAP1,CPXM1,OR4A47,TMEM100,DCTPP1,TLCD1,AQP11,RBP2,KCTD17,CLEC6A,RASSF8,SSBP4,OR13A1,MAGEC2,PSEN1,LMO2,FKBP1B,LCORL,EDA2R,ANKRD6,PDE12,FAM161A,YTHDF2,MREG,ACER3,DIRAS2,SRFBP1,ARHGAP12,PFKFB2,EIF5B,ZFAND6,TYMS,TAPT1,SCML1,GJC1,RUNX1,SLC12A2,NAA16,VPS18,GHRL,KIF3C,CIAO1,ATP8A1,DUSP3,PDE7A,SUCLG2,ZNF581,RPL18,TKTL1,GIN1,KRIT1,VPS72,FUBP3,KCND3,ROCK2,TRAF6,TBCCD1,CLDND1,ETNK2,CCDC106,SPRY1,RPS10,TMEM196,UBA52,FUNDC1,ECHDC1,AP1M1,TRAM1,TADA3,IMPA2,ITM2B,MTCH2,CCSER2,TRAPPC6A,MDC1,MGMT,SLC35E4,ADCK1,CYBRD1,ZNF518B,FAM151B,OAZ1,LYZ,WSB1,SLC25A5,IRF7,VEZT,SLU7,MFAP3L,FAM3C,PTP4A2,SULT1B1,RPE,OR8B4,TMEM165,KLHL25,CENPL,IER3,TRIM26,NUCKS1,RAMP3,TMBIM1,CPNE2,IFT172,CYTH4,TOX4,KLRC2,UPRT,SUPT3H,FXN,MRPL9,FEM1B,MRPS17,SGIP1,MECR,SNAP25,RXRG,IGF1,CCR7,PELO,GMPS,TTC9C,GORASP2,THUMPD1,GALNT2,ANXA4,RASL12,IL18BP,GRIK1,DLGAP4,CMA1,SNRPE,RRAGB,NKAP,LBX1,GALC,ELFN2,RP9,OR5M9,HAUS2,GNGT2,SSPN,CNPY1,LRRC8A,PIH1D1,KCTD3,RDH11,MPG,SYNGR3,TANK,BRAP,CDC23,MBD3,ELFN1,DMPK,PDLIM4,THG1L,ERCC3,GABBR1,GPR34,TBC1D1,TIMM13,RPF2,XBP1,EMILIN3,DRD3,MTA3,CEACAM5,NAP1L3,NACC2,CHRM5,OSBPL8,CEP57L1,ARHGAP19,TACR1,DIS3L,CA14,MED4,ZCRB1,CYB5B,TRMT5,OR9I1,BCKDK,SEMA7A,NAP1L5,LIPT2,HPCAL1,MRGPRX1,STT3A,MAGEA4,RACGAP1,CORO1C,CCDC126,RRP7A,RBM3,ERLIN2,HYAL2,RHOH,ARHGAP15,RPSA,PIK3CG,NPBWR1,FOSL2,GNPAT,ACP2,ACTL6A,GPR75,SETD3,TMEM126A,CHTOP,SYPL1,WBP11,ZNF436,DIO2,STARD7,ZNF343,ANKRD10,TEF,SCN2B,SOD2,ADD2,TMEM231,PCP2,TCTA,IAH1,WDR12,MLN,KLF12,CNOT8,PELI1,PIGK,FBXO31,MAP1B,ZDHHC17,PDCD1LG2,GLO1,RAB1A,VSTM4,AMELX,ECD,CD59,PSMG4,RIMKLB,AQP3,ETFA,APMAP,PRELID1,GPM6A,COTL1,PNPO,OR2D3,RFC4,LCN1,TLR5,TICAM1,HS3ST3A1,AKT2,JMJD8,ITPRIPL2,GAB1,PSMC5,PRSS1,APEX1,SOX9,KCNG3,CHST10,REG1A,C1QL2,PLCXD3,TSPYL4,DNM2,OR4K13,GTF3C4,MMP20,DCAF16,SRD5A3,CLRN2,SUGP1,ABCC2,FMO1,STARD5,DEXI,ALG5,HTR2A,SMARCB1,STAP1,ACTR1B,WTAP,PDCD10,SSBP2,GDAP1L1,CRHR1,AKR1E2,UQCRC1,NOC4L,BAD,TSPAN3,MGST3,PRPS1,HAS3,OLA1,ZMAT3,BRS3,SKAP2,CLK1,RASSF4,KCTD20,SERPINA3,TRAF1,RSL24D1,HSD17B8,IRF9,LSM4,CGRRF1,DDX39B,HERC3,PSMB4,DOK6,SEMA3C,C9orf72,NAA30,NETO1,PTGER2,CDR2,NCK1,SIAH1,LRP3,STRADB,CD200,USE1,ST8SIA4,TMEM168,HNRNPAB,GPR78,TRIM62,ZNF655,TEX19,KCTD16,SLC15A1,ZBTB6,AHSA1,PLEKHF1,HMGN4,SCHIP1,TAF9,MEA1,CDKN1B,COX7B2,CMBL,TMEM198,TRAPPC2L,RFX5,NMRAL1,MAT2A,OR6C4,PHOSPHO2,SCG5,PDE6A,HELT,IMP4,SNX11,RPLP1,TIMMDC1,UBE2V1,SERPINB9,GAL3ST4,ADIPOR1,SLC7A11,RETSAT,POPDC3,FZD6,MET,HOXB8,SSH3,EMX2,SEC61G,CENPM,GFM1,PDLIM3,PRSS37,MAP1LC3B,ACSS2,IFRD1,RANBP1,ATF3,RBM5,CTLA4,RPL22,CEBPE,TMEM176B,RHOU,B3GALT4,DLG3,AANAT,HAPLN2,EDC3,F2,ARL5B,ESYT1,CAMKV,YKT6,VPS26B,ANKH,MFSD3,BIRC5,GMDS,WNT2,LDB1,CSRNP3,TRAPPC3,KDM1A,NDFIP1,CCDC22,CTDSPL2,ARL6IP5,CEP70,ABHD2,SNRPA1,SNN,PSMG2,DTL,TMEM87A,RALB,ISG20,NUDT1,CYP26A1,GMNN,TBCEL,PRSS35,FKBP2,UNC45A,UBE3A,S100B,TNIK,LRFN3,OR4B1,OR5K1,PDZK1IP1,PDE6D,IFNA13,CACNG3,RIT2,PITHD1,LEP,SH3BP4,EFNA5,ASPM,ZC3H14,TADA1,CETN2,ZC4H2,RPL7A,CXXC1,FIG4,LSM12,DOK5,MAP2K3,SEC22A,DCTN4,ARF6,B3GALT2,PPT1,ZDHHC24,RCHY1,SPHK2,FAM20C,FGR,MRPL12,MRPL16,TECR,EZH1,ARGLU1,FHIT,ARL11,KRTAP4-1,MAP3K3,MXD1,MFAP1,UCP2,TMEM106B,UBE2I,MED29,PNRC1,SLC41A1,SERINC1,SNRNP70,PLEKHF2,TDP1,MID1IP1,GLIPR2,ZNF362,HBM,FGF16,POU5F1,MSN,DDIT4L,RNASE4,SAP30,SLITRK5,IL21,RPL19,DICER1,MAGEB1,SLC6A7,CXCL10,KIAA1958,EID2,ZNF345,MAEA,FOXD3,FBLN5,LYRM2,DUSP18,RPS28,UBXN2B,ZNF770,TPD52L1,ASCC1,CDH7,SLC37A4,SMUG1,SVIP,GAD2,RSBN1L,METTL18,TTR,SEC61A1,FAM83A,RHOG,NOL12,SDHC,RGS1,ASB11,BGLAP,COX7B,CDC42SE1,EMILIN1,PRDX3,PDCD5,ZBTB26,LRRC14,BTBD10,ARF1,EIF2B2,ZMYM6,THAP6,TUBA1B,MRPS26,PHF7,HMGB1,FA2H,ERRFI1,HNMT,ZHX1,SERTAD1,KCNIP2,LPCAT3,GPR83,DPAGT1,CTSA,PPIL3,PHTF2,ZCCHC7,TTLL10,TP53TG5,DIRAS3,HDAC11,SIGLEC5,ATG16L1,LCP1,AGGF1,HNRNPH3,ZNF200,IZUMO2,TPST1,CHCHD2,GCHFR,GJB1,KRT8,PRELP,CSF2,PCYT1B,HCFC2,PABPC5,IRF2BPL,PRKCB,DCTN3,LSM5,COPE,RBM41,RWDD1,SLC25A3,SPAG11B,HBP1,DYNLRB2,CKS1B,SUV39H1,RGL1,RPL4,SEC14L5,APOBEC3B,FAM193B,PCBP4,MLH3,CRYBA4,PITPNA,FOXC2,CRYZ,BLVRA,RANBP10,SRM,MED27,ADH1B,MPP1,PSMD1,BARX2,HS3ST1,TULP3,SPDYE4,OR4M1,BMPR1B,CFTR,INA,ATG3,OR5AN1,CLP1,CLPX,SART3,IFI16,PTPRZ1,VPS39,SUPT4H1,MYLIP,ART5,TMEM39A,CDK17,CHMP1B,PSMB10,VWF,ESD,GPR37,CDKN2D,ATP6V1D,SLA2,SDR16C5,IFNAR1,MARCKSL1,RXFP2,RAB9A,RPAP3,CCL11,TNPO2,PYCR1,THOC6,HINT1,DYNLL1,NUP62,SMG5,RNF139,DUS4L,ABCF1,PLP2,OPRL1,HSDL2,LYPLAL1,CSRP1,LEMD3,STX5,RAB11B,ARL6,CCND3,FMOD,ADRB3,CMTM7,SPATA4,CA12,SLC7A1,TBC1D16,SHC3,PREP,CYP4F22,ARFGAP1,PIGC,MVD,STK38L,FIS1,EDEM2,CACNB2,HCFC1R1,RPL28,SRP72,DDIT3,SLITRK1,VCPIP1,OAZ3,PGAP3,MB21D2,LCN15,SLC39A10,HM13,BCAS4,TCEA1,LIPA,PTPN5,UFSP1,TIMM17A,SMAD9,RELL1,RNF182,ALCAM,SNRPD1,CCL24 |
| 1.017e-03 | -6.89 | Senescence and Autophagy in Cancer | WikiPathways | WP615 | 106 | 54 | 5310 | 1910 |
IL3,CCL3,ATG7,RNASEL,RB1,TP53,HMGA1,PCNA,IRF7,IRF1,CXCL8,MAP1LC3A,MMP14,FKBP8,SQSTM1,CDKN1B,IGFBP3,IL1A,ING2,SRC,GABARAPL2,GABARAP,IFNB1,IFNG,TNFSF15,MAP1LC3B,RB1CC1,SLC39A3,ING1,MDM2,SMAD4,LAMP2,IGF1,MAP2K1,IL6,ATG16L1,MAP2K3,ATG3,SH3GLB1,SMAD3,CXCL14,IFI16,IL6ST,GABARAPL1,BECN1,COL3A1,CDKN1A,RAF1,HRAS,PTEN,IL1B,CXCL1,IGF1R,JUN |
| 1.018e-03 | -6.89 | cytoplasmic ribonucleoprotein granule | cellular component | GO:0036464 | 254 | 97 | 19108 | 5553 |
PSMA4,UHMK1,TUBA1A,CDK9,TAF5L,G3BP1,YTHDF2,PIWIL4,LSM2,DCP2,DYNC1I1,G3BP2,HNRNPK,LSM14A,EID1,MAEL,MCRIP2,EIF4E2,LARP4B,DDX1,LSM3,CNOT2,INA,APOBEC3G,RPL6,PIWIL2,DDX4,ACTB,YTHDF1,ROCK2,TIA1,ANKRD34B,NUFIP2,STAU1,TDRD7,PQBP1,USP3,PABPC1L,POLDIP3,TRIM21,EDC3,ASZ1,FXR2,SNRPB2,RPS4X,PIWIL3,SNRPG,APOBEC3F,EIF2S1,ROCK1,PSMA2,GHR,SMN1,TNRC6C,APOBEC3D,C9orf72,APOBEC3C,SQSTM1,CNOT7,MYH1,DHX9,GARRE1,GABPB1,PABPC5,IGF2BP1,PSMC3,RPLP0,LSM4,PSMA6,PNRC1,CIRBP,HAX1,LSM6,TOP1,CMA1,APOBEC3H,CARHSP1,CDC42,PABPC1,RC3H2,AGO1,MOV10,HENMT1,TUBB,CPEB1,EIF4EBP2,PIWIL1,POLR2G,APOBEC3B,CNOT8,CASC3,ISG20,APOBEC3A,RPL28,SERPINB1,TRIM5,EIF4E |
| 1.022e-03 | -6.89 | toll-like receptor signaling pathway | biological process | GO:0002224 | 46 | 24 | 18204 | 5365 |
TLR4,MAPKAPK3,TLR8,TLR6,IRF3,TLR5,CD274,TRAF6,MYD88,BCL10,HSPD1,TLR2,IRAK4,TICAM2,TLR10,TLR9,LY96,PRKCE,IKBKB,TLR3,TIRAP,TLR1,TICAM1,TLR7 |
| 1.022e-03 | -6.89 | response to acetylcholine | biological process | GO:1905144 | 46 | 24 | 18204 | 5365 |
GNAI2,LARGE1,RGS10,GNB1,PLCB1,TSPO,CRKL,CDK5R1,OPRM1,CHRM5,ROCK2,EDNRA,ATP2B4,ACHE,CHRM1,CHRNA7,GNA11,CHRNB2,GNAQ,CHRM3,PRKCB,CHRM4,LY6H,HRH3 |
| 1.023e-03 | -6.89 | PEAK1 (pseudopodium enriched atypical kinase 1) | protein interactions | 79834 | 144 | 58 | 19454 | 5460 |
RAF1,CRKL,RND3,RAB4A,NTRK2,IGF1R,GADD45A,ZYX,S100B,FLOT1,RIGI,KRAS,YWHAH,YWHAG,ATG9A,LAMP2,YWHAB,SHC1,AGR2,RHOG,RAC2,GJA1,RAB35,CAV1,DIRAS3,STX6,EGLN3,RHOH,ARF6,RND2,CDC42,FGFR1,RAB5A,RAB9A,XRCC5,RHOU,TOMM20,STX7,SLC31A1,PPP1CC,DNAJC5,SFN,RAB11A,RAB2A,CSK,RHOB,YWHAZ,LAMTOR1,ANAPC2,GSK3A,CTNNA1,FBLN5,CTTN,ESR2,VIRMA,MAD2L1,ACTB,RHOJ |
| 1.023e-03 | -6.89 | RPRD2 (regulation of nuclear pre-mRNA domain containing 2) | protein interactions | 23248 | 144 | 58 | 19454 | 5460 |
POLR2L,RPRD1A,PRNP,TOP1,POLR2I,MIF,HNRNPL,MPG,XPO1,CSNK2A1,MED27,MED21,MED4,BAG2,RPAP3,DNAAF10,TRIM37,SSRP1,MDC1,PDRG1,SUPT5H,RPAP2,POLR2G,POLR2C,POLR2D,CCNF,S100A6,POLR2F,POLR3H,POLR3B,MED17,VIRMA,POLR2B,LMO2,MYC,PPP1CC,AR,SNRPB,MYO6,SPOP,MED10,POLR1B,PFDN2,RPA3,SNRPA,NUP50,HSPA8,ELOF1,B9D2,DGCR8,AATF,POLR1H,H1-5,POLR1D,RPA2,CTDSP1,RPRD1B,PIH1D1 |
| 1.024e-03 | -6.88 | RNA biosynthetic process | biological process | GO:0032774 | 539 | 192 | 18204 | 5365 |
DRAP1,PRIM2,GTF3C4,GTF2I,TCEA2,NR4A2,GTF2E1,POLR2L,MNAT1,EGR1,SMARCB1,BCL9,IVNS1ABP,DEK,PPARG,NIBAN2,SNAPC2,MLF1,CCNA2,GTF2IRD1,PIK3R1,IRF1,VPS72,EPOP,ELOF1,MEF2A,SUPT4H1,ADRM1,NCBP2,DDX5,TAF7,TAF10,ERCC3,TP53,MED17,APEX1,KLF4,POLR1B,TCOF1,POLR1H,POLR2F,ATF4,POLR2G,SQSTM1,ATXN1L,GTF2H2,HELT,SMARCA5,NFKB1,GTF2E2,TERT,TFB1M,SUPT3H,RB1,OGG1,NFYA,TFCP2,SUPT5H,FOS,MED4,CDK9,POLR2B,SPHK2,RPAP2,WBP2,MRPL12,APOBEC3A,CCNH,GTF3C3,CEBPG,NDP,LDB1,TAF9,TRMT112,MED9,MSX1,MED23,ELOC,PPP1R1B,TCEA1,FOXA3,MED11,PKNOX1,S100A10,EAF2,HINFP,SGF29,APOBEC3C,MED22,GTF2A2,SSU72,PLAC8,BCL6,PIR,MED10,MED30,POLR3F,CBFB,CD28,MED27,GTF2A1,NCAPG2,POLR3H,SNAPC3,GPBP1L1,PAX6,MED29,WNT10B,APOBEC3F,WDR82,POLR2I,CDC73,THAP1,ZMPSTE24,HDAC3,PAAF1,IRF9,TAF2,GTF2H4,SMAD2,CREBL2,TAF5L,GTF2F1,CREB1,MARS1,PADI2,NKX3-2,POLR2C,POLR3B,WWP2,POLR3GL,GTF2F2,BARX2,MED21,USP15,NFIL3,SMN1,COPS2,FOXP3,POLR2D,POLR1D,KPNA6,RPRD1A,MED31,SMAD1,PPP5C,JAK2,TAF11,NR1H2,MACROH2A1,TOPORS,CDK12,HIRA,CYTL1,POLA2,IL2,RRN3,AR,CDK7,TRIM24,SNAPC5,XBP1,SUB1,MTF1,SOX9,SART3,CTNNB1,TWNK,VDR,SNAPC1,TCEANC2,RPRD1B,EP300,DR1,ENY2,DPY30,GTF2B,SIRT7,GTF2H5,SKIC8,MTERF2,PRMT5,FUBP3,PRDM4,PROX1,ZNF345,ADRB2,SMAD4,CEBPE,NFKBIB,DHX9,NPM3 |
| 1.028e-03 | -6.88 | CCT6B (chaperonin containing TCP1 subunit 6B) | protein interactions | 10693 | 195 | 75 | 19454 | 5460 |
SKIC8,DCAF5,AHSA1,DCAF11,WWP2,DCAF4L2,HDAC6,TCP1,DYNC1I2,CCT7,TRMT61A,EGLN3,EEF1AKMT3,ACTR2,MMACHC,EZH2,KLHL26,PPP4C,TP53,CCT5,WDR37,ACTR1A,MAPK10,TUBA1A,FARSA,DNAAF10,KDM4B,GXYLT2,DUSP19,STRADB,UBE2A,DUSP21,CCT8,METTL18,ACTR1B,HECTD3,LMNB1,PELI3,CCT2,PLA2G15,RAP2C,DTL,COP1,CUL3,KLHDC8A,LDHB,PTPN11,MYC,PRDX2,CYP27A1,LDHA,BUB3,GNB1,TUBA1B,METAP2,UQCRC2,UBASH3B,VRTN,TRIM68,WRAP53,HECTD1,HEXIM1,EIF4B,ACTL6A,WDR77,WDR83,WDR5B,ATG16L1,MTMR6,SPMIP6,PPP2R2C,IDH3A,HCFC2,FBXW4,THOC3 |
| 1.031e-03 | -6.88 | ND5 (NADH dehydrogenase subunit 5) | protein interactions | 4540 | 64 | 30 | 19454 | 5460 |
MRPL50,PRNP,PARL,NDUFA1,FUT1,MRPL18,SPOP,NDUFB8,BAX,BAK1,NDUFB7,NDUFV2,DNAJC30,HSCB,GLUL,TSPAN15,DVL2,NDUFB5,NDUFC2,TACR1,AQP3,NDUFS3,NDUFS6,VAPB,GPR34,NDUFA12,CRELD1,TP53,YIPF3,MGARP |
| 1.031e-03 | -6.88 | SGK3 (serum/glucocorticoid regulated kinase family member 3) | protein interactions | 23678 | 64 | 30 | 19454 | 5460 |
ICAM1,EXOSC1,HSP90AA1,AKT3,MRPL16,CTNNBIP1,ELOC,ST13,PRNP,CACYBP,NCKAP1,CCNF,AIP,CD79B,GYS1,GSK3A,ATP5PO,UBE2M,MRPL49,TRMT1L,ATP5PB,CCT5,MRPL12,MAPK1IP1L,CCDC186,ROCK2,MCM6,DNLZ,MAP1B,PRDX6 |
| 1.031e-03 | -6.88 | TM9SF2 (transmembrane 9 superfamily member 2) | protein interactions | 9375 | 64 | 30 | 19454 | 5460 |
SLC25A3,PLD3,RPA2,LMNA,GP9,SFTPC,ISG15,CLEC2B,CFTR,PTAR1,TP53,LPAR1,RAB9A,SQSTM1,SRSF7,RPA3,RAB1A,TMEM106B,MARCHF3,AQP2,SMAD4,ATP1B3,CGRRF1,ATP1B1,RAB2A,RAB11A,TAX1BP1,ST8SIA5,S1PR4,LMBR1L |
| 1.036e-03 | -6.87 | KLHL26 (kelch like family member 26) | protein interactions | 55295 | 75 | 34 | 19454 | 5460 |
KLHL3,ISG15,DDX39A,NUDCD3,IPP,FEM1A,CD209,KLHL12,UBE2M,CCL21,DNAL4,KLHL28,HSPA8,DNAJB4,CAMK2G,ENKD1,ANKMY2,MZB1,CUL3,KLHL9,UBXN6,KLHL22,FAM241A,COPS5,CCT2,IGFBP4,HSP90AA1,FAM219B,CRYBB3,SPINT2,HNRNPL,DCUN1D1,KCTD9,TRMT61A |
| 1.036e-03 | -6.87 | GNG5 (G protein subunit gamma 5) | protein interactions | 2787 | 75 | 34 | 19454 | 5460 |
PREB,DUSP22,CYB5R1,PRDX3,VAPB,GNAI3,NUPR1,GNAQ,SLC25A3,SLC25A20,PDCL,GNA11,RAB1A,HADHA,ABCE1,SLC16A1,PHB2,KRAS,FKBP8,GNB4,RAB11A,MDFI,CD81,FYTTD1,OCIAD2,NFKBIA,CYB5R3,GNB3,SPRED2,SEC61B,GNB1,GNAI2,TRAF1,PPP1R3C |
| 1.036e-03 | -6.87 | RFWD3 (ring finger and WD repeat domain 3) | protein interactions | 55159 | 75 | 34 | 19454 | 5460 |
LYAR,TCP1,CCT7,LRWD1,MDM2,UBE2N,CSNK2B,PIP4K2C,UBE2E3,UBE2D1,CCT2,HSP90AA1,PFDN2,DNAJB2,PRPF19,MOV10,XPO1,FBXW7,UBE2D3,COA1,RNF41,PFDN1,CCT8,RPA3,HSPD1,PCNA,DISC1,HSP90B1,RPA2,CCT5,UBE2W,TP53,LGR4,CFTR |
| 1.036e-03 | -6.87 | BCAS3 (BCAS3 microtubule associated cell migration factor) | protein interactions | 54828 | 75 | 34 | 19454 | 5460 |
JUN,CCND1,TP53,TOP3B,CD14,SCLT1,VPS33A,RPA2,CTBP1,MTDH,IRF3,RPA3,ZDHHC17,STAU1,FBXW7,H3C1,KRAS,YWHAH,YWHAG,XPO1,CDC23,STK11,SMAD4,POLR3H,TSG101,PPM1M,PHB1,CCNF,PTPN1,PELP1,VIRMA,APEX1,PLEKHF2,HNRNPL |
| 1.036e-03 | -6.87 | MTX3 (metaxin 3) | protein interactions | 345778 | 75 | 34 | 19454 | 5460 |
LAMP2,SYP,FIS1,SLC20A1,LMBR1L,TNFRSF1B,CHCHD3,APLNR,PLGRKT,COX14,TOMM22,RPS14,MTCH2,MTX2,SNRNP27,APOO,FAXC,LPAR6,MGARP,GTF2E2,SLC22A8,AQP3,CXCR4,SLC39A9,SFXN1,SLC2A8,SLC22A6,BSCL2,AKAP1,HSCB,TNF,SLC15A1,DUSP21,SLC5A6 |
| 1.036e-03 | -6.87 | MICU1 (mitochondrial calcium uptake 1) | protein interactions | 10367 | 75 | 34 | 19454 | 5460 |
DCAF8L2,RPA2,PDHA1,APOO,PHB2,DNAJC30,SLC25A51,IMMP2L,CXCR4,SFXN1,AKAP1,TEX19,DCAF11,UBE2H,CSK,BABAM1,ZCCHC10,CUL3,KLHL22,HNRNPL,RANBP6,PRNP,EIF2B5,APEX1,COX14,ESR2,SLC25A12,PARL,TRIM44,CD79B,AIFM1,TUBA1B,ARL10,COX4I1 |
| 1.036e-03 | -6.87 | ADIPOR2 (adiponectin receptor 2) | protein interactions | 79602 | 75 | 34 | 19454 | 5460 |
ARL6IP5,ILVBL,HSP90AB1,STT3A,HACD3,CYB5R3,DUSP6,PSMC5,GGT7,POR,NCK1,YWHAZ,CCDC174,RAB2A,RETSAT,RAB5C,HMOX2,TMBIM6,EMC1,TMEM33,ADIPOQ,RDH11,NSDHL,HAPSTR1,PDIA6,UBAC2,EPHX1,LEMD3,RNF181,DCAKD,PGRMC1,SEC22B,FAF2,ERLIN2 |
| 1.036e-03 | -6.87 | ZNF830 (zinc finger protein 830) | protein interactions | 91603 | 75 | 34 | 19454 | 5460 |
SESTD1,SNRNP40,THOC1,CDC5L,PSMB6,FRA10AC1,PRPF19,MYC,SNRPB,XPO1,MRPS16,RIT1,PTTG1,SNRPA,ARPC2,EMC2,NUP50,CLK1,KRAS,H3C1,CTNNBL1,SSRP1,RPL28,SF3A1,MRPL10,IK,RAB4A,FEM1A,CBX3,CDK8,RPA2,LMNA,SNRPE,MFAP1 |
| 1.037e-03 | -6.87 | KNSTRN (kinetochore localized astrin (SPAG5) binding protein) | protein interactions | 90417 | 89 | 39 | 19454 | 5460 |
TEDC2,LPAR2,HSPA8,OIP5,TRIM37,SGF29,CHMP1B,RIGI,CLU,HSPA5,ZDHHC17,RAF1,GNG10,BORCS6,SOX2,COMMD3,IFT57,PALS2,SHOC2,NUPR1,ACACA,TRIM36,ENO1,TRIM24,KRT8,DYNLL1,SPPL3,COPS7B,KXD1,MOV10,SYCE3,PRPF19,PPP1CC,RNF40,CCDC22,HSPB1,CAMSAP2,MAPRE1,MPHOSPH6 |
| 1.037e-03 | -6.87 | SLC25A41 (solute carrier family 25 member 41) | protein interactions | 284427 | 89 | 39 | 19454 | 5460 |
RALA,RAB14,FCHO2,YES1,SRC,HRAS,AP2M1,TSG101,CETN3,CDCA3,AP2A1,BOLA1,EPHA2,TMOD2,RAB2A,ACTR3B,BTF3L4,RP2,VPS28,GNA11,HSPD1,LIN7C,SPECC1L,GNG5,STK26,NUDT19,GNG7,RPRD1B,PICALM,MFAP1,PRKCA,TMOD1,STAMBP,GNAQ,CSNK1G3,GNAZ,CD2AP,HPCAL1,GNG10 |
| 1.037e-03 | -6.87 | INSRR (insulin receptor related receptor) | protein interactions | 3645 | 89 | 39 | 19454 | 5460 |
OSBPL8,DEFB116,NSA2,HSP90AA1,VCPIP1,DNAJC10,CHP1,HSP90AB1,MRPS23,SPPL3,S100A8,PTPN1,SRPRA,GNG12,AIP,LEMD3,OTULIN,PRKCA,IDH2,ACVR1,STIM1,VAPB,ZMYM3,CTDSP2,DCAKD,FKBP8,CXXC1,ARF4,NOP53,ACVR1B,PIK3R2,SRPRB,MTDH,IGF1R,RAB13,MYO1B,JAK1,DDR1,BMPR1A |
| 1.038e-03 | -6.87 | DPY30 (dpy-30 histone methyltransferase complex regulatory subunit) | protein interactions | 84661 | 189 | 73 | 19454 | 5460 |
SAP30,NUP153,ARFGEF1,CSNK1E,MTA3,PSMC3,PHC1,FAM136A,MTA2,PIK3CA,AKAP14,MRFAP1,HNRNPA2B1,RERE,CPLX1,MDC1,SSRP1,PAGR1,KRAS,ZNF207,CSNK2A1,DPY30,HMGA1,POU5F1,SMAD9,KDM2A,BCAS4,FOSL2,MYBL2,WDR82,H2AZ1,TMCC2,MBD5,BRMS1L,TOP1,MEAF6,CDK17,CNPY3,CCND1,HECTD1,LMNA,MEA1,HCFC2,BANF1,BAP1,CXXC1,MBD3,PSMC1,CHMP2B,FBXW7,GTF2I,AR,PPP1CC,MTPN,H2BC9,CCNB1,CUL3,SMARCA5,MYC,RIT1,UBE2H,SETD7,PSMD14,BRCA1,CHORDC1,SNRPD1,IRF2,MAD2L2,VIRMA,RBBP4,FBXO22,CFAP91,MATR3 |
| 1.041e-03 | -6.87 | COQ8B (coenzyme Q8B) | protein interactions | 79934 | 109 | 46 | 19454 | 5460 |
DUOXA2,EGLN3,ATP5PD,PRNP,FAHD1,COQ8A,TIMM8B,RHOG,SLC2A1,P2RY10,STOML2,IMMP2L,RASL10B,TGFBR2,CHCHD2,IGF1R,CLPB,AQP3,TMEM165,MGARP,ATP5PB,APLNR,SLC1A1,MTG1,CCNF,DNAJB6,GPR17,CUL3,PMPCA,MTG2,MRPS7,POLDIP2,NPTN,HSCB,PRKCB,VIPR1,ATP5F1E,EXD2,AMACR,SSR1,ATP5PO,QRSL1,TIMM13,CDC42,HCST,COQ8B |
| 1.041e-03 | -6.87 | MBP (myelin basic protein) | protein interactions | 4155 | 109 | 46 | 19454 | 5460 |
ADRB2,PRKCB,CLK1,STK26,SQSTM1,RTN4,PRKCA,ZER1,CTDSP1,CDK1,MAP2K1,DUSP22,CDK7,MAPKAPK5,IDE,ROCK1,VIRMA,MAP3K3,PRMT5,PLP1,RAN,ILK,CTSD,IRAK4,RIGI,ROCK2,CDK5,NEK9,CCR1,STK16,APTX,CDK8,CTDSP2,RAF1,TBK1,CDK9,STK3,PLEKHF2,HNRNPL,HRAS,CDK12,FBXO34,TRAF6,NCK1,STK4,DYRK1B |
| 1.041e-03 | -6.87 | BUD31 (BUD31 homolog) | protein interactions | 8896 | 109 | 46 | 19454 | 5460 |
PRPF19,TRA2A,KIAA1143,ID1,SNRPA1,TOP1,CDC5L,TPBG,RAF1,RPS7,CBX3,TMEM94,SNIP1,RPL31,SRSF7,RPS24,SEPTIN7,PICK1,KRAS,TSSC4,H3C1,CTNNBL1,HTR5A,TSPAN7,HNRNPC,CUL3,RIT1,RNF208,ZNF330,ESR2,VIRMA,SNRPN,BEND5,PABPC5,WDR83,ZNF326,LSM2,PCLAF,LMNA,NKAPD1,SNRPA,NUP50,HMGB1,RNASE1,SGF29,COIL |
| 1.042e-03 | -6.87 | U6 snRNP | cellular component | GO:0005688 | 8 | 7 | 19108 | 5553 |
LSM8,LSM3,LSM2,LSM6,LSM4,LSM5,DDX39B |
| 1.042e-03 | -6.87 | BORC complex | cellular component | GO:0099078 | 8 | 7 | 19108 | 5553 |
BORCS7,KXD1,BORCS8,SNAPIN,BLOC1S2,BORCS5,BORCS6 |
| 1.043e-03 | -6.87 | TSNAX (translin associated factor X) | protein interactions | 7257 | 186 | 72 | 19454 | 5460 |
FAM133B,PRDX1,SYNCRIP,SPRED2,PTPN1,DYNC1I2,HNRNPL,FZR1,CETN2,NUF2,PRPF18,AKAP17A,ATP5PD,TP53,NAA15,TOP3B,TPD52,UBR7,GGCT,KIF2A,MAK16,PSME1,FSTL1,MRFAP1L1,HAPSTR1,HNRNPK,ACVR1B,HNRNPF,RIGI,CAPZA1,RNF20,CUL3,EMILIN1,MCM3,RFC5,NTAQ1,FAS,BEX3,BLOC1S5,PDF,RAN,RPS3,UBE2I,RPS20,SMU1,TRIM27,RRAS2,PSMD6,DYNLL1,ADRM1,TSN,STAT1,LDB2,VIRMA,TAF11,GADD45G,TXNL4A,RPS14,RALYL,TCP11L1,HEXB,LACC1,EIF4B,BAP1,RPA3,C1D,RAMAC,ARFIP1,MCMBP,FXR2,VPS28,LDOC1 |
| 1.043e-03 | -6.87 | STRN4 (striatin 4) | protein interactions | 29888 | 153 | 61 | 19454 | 5460 |
CTTNBP2NL,ESR2,NDN,DYNLL1,RMDN3,MOB4,PLP1,CTTN,MTG1,RIT1,CCT2,STK24,NONO,ISCA2,FGFR1OP2,PPP2R2C,FXR2,HSCB,STK26,RPA3,DDX39B,WNT7A,TMOD1,TOX4,RPA2,ATG16L1,SLMAP,CAV1,STK3,CEP19,AK5,MIF,PRNP,PBDC1,KRT8,TNIK,EEF1B2,DFFA,TRAF3IP3,EEF1AKMT3,PPP2CB,PDCD10,USP15,STK4,PRPF19,HMGA1,MOV10,RIGI,PSMA5,CAMK2G,CTTNBP2,HSPD1,SIKE1,CLDN12,RPL18,PPP2R1A,EEF1A1,JUN,TULP3,TOP3B,SNAP29 |
| 1.043e-03 | -6.87 | RASAL2 (RAS protein activator like 2) | protein interactions | 9462 | 153 | 61 | 19454 | 5460 |
RHOJ,VIRMA,TRAF1,NFKBIB,GSK3A,LAMTOR1,YWHAZ,RHOB,MYC,RAB2A,FAM110B,RAB11A,SFN,MAP3K21,DNAJC5,HMGB1,STX7,RHOU,RPA3,RTKN,FAM53C,MIA2,RAB9A,LCP1,FGFR1,CSNK1A1,AGAP1,INPP5E,CDC42,RND2,SIPA1L1,ARF6,KCTD3,RHOH,PRNP,STX6,LMAN1,DIRAS3,CAV1,HRAS,RAB35,EIF4E2,GJA1,RAC2,RHOG,SHC1,TIAM1,YWHAB,CAMSAP2,DPP4,YWHAG,YWHAH,KRAS,TRIM37,SRSF12,FLOT1,BAG2,TESK2,RND3,CSNK1E,KIF1C |
| 1.044e-03 | -6.86 | ASH1L (ASH1 like histone lysine methyltransferase) | protein interactions | 55870 | 48 | 24 | 19454 | 5460 |
VIRMA,HNRNPL,PRNP,EIF2B5,VPS26C,RBBP4,FGFBP1,EFNA3,LURAP1,OXTR,AGR2,RHOB,DCAF4,THAP7,H2BC9,MORF4L1,RPL28,FTL,H3C1,RPL23A,GID8,SIKE1,PARD6A,RPL15 |
| 1.046e-03 | -6.86 | STK26 (serine/threonine kinase 26) | protein interactions | 51765 | 183 | 71 | 19454 | 5460 |
ARFGEF1,ATP5PB,RAF1,PPP2R1A,CAPZA2,ARPC3,ACTR2,CCM2,PPP4C,CAPN2,GLUL,SIKE1,CTTNBP2,SCPEP1,TTC4,DUSP19,CAPZA1,FAM174A,FAM20C,UBXN6,LAMP2,DDRGK1,COPS5,GNG2,TRAF6,DDX23,SMAD4,IKBKB,ANKRD49,PDCD10,TRAF3IP3,PPP2CB,RPL12,CCAR2,ZBTB2,CDK9,SLMAP,POLE3,SF3A1,CFTR,IGFBP3,PPP1CB,SNRNP27,ISOC1,RPA2,BAP1,RPA3,MAVS,ARPC2,EP300,STK26,NPTN,HSPA5,UNC45A,RGS2,FGFR1OP2,STK24,DNAJB6,CTTN,LMBR1L,S100A6,SRP54,TRIM27,MOB4,MED17,DYNLL1,MATR3,NCKAP1,ESR2,CTTNBP2NL,HOMER1 |
| 1.048e-03 | -6.86 | central_nervous_system-brain-glioma-gliosarcoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-gliosarcoma | 16 | 11 | 16828 | 4835 |
CTNNB1,KRAS,HRAS,KIT,TP53,CDKN2C,IDH1,IDH2,TERT,PTEN,SF3B1 |
| 1.048e-03 | -6.86 | neurocristic_hamartoma | COSMIC cancer mutations | neurocristic_hamartoma | 16 | 11 | 16828 | 4835 |
GNAQ,PIK3CA,PTEN,KRAS,CTNNB1,HRAS,KIT,TP53,AKT1,IDH1,JAK2 |
| 1.048e-03 | -6.86 | pineal_gland | COSMIC cancer mutations | pineal_gland | 16 | 11 | 16828 | 4835 |
SMARCB1,DICER1,EZH2,TERT,IDH2,EWSR1,GNAQ,IDH1,MSH6,KRAS,HRAS |
| 1.048e-03 | -6.86 | skin-other-neurocristic_hamartoma | COSMIC cancer mutations | skin-other-neurocristic_hamartoma | 16 | 11 | 16828 | 4835 |
AKT1,IDH1,JAK2,TP53,CTNNB1,KRAS,HRAS,KIT,PTEN,PIK3CA,GNAQ |
| 1.049e-03 | -6.86 | regulation of protein ubiquitination | biological process | GO:0031396 | 201 | 80 | 18204 | 5365 |
TSPO,CDKN1B,HDAC3,CUL3,HSPA5,TRAF6,NDFIP1,TOPORS,ARRDC3,UFL1,SKP1,PLAA,UBE2N,DNAJB2,UBE2S,UBE2D1,BEX3,RPL23,RPS2,PSMD10,MAD2L2,NSMCE3,DCUN1D1,PTEN,TICAM1,PHF23,CAV1,MAD2L1,RBCK1,KDM1A,IVNS1ABP,TRIM44,NMI,CDK5RAP3,PRKCE,HSP90AB1,WBP1L,CRY1,GSK3A,DERL1,UBE2V1,GCLC,STUB1,PTPN22,UBE2V2,FAM107A,AKT1,BCL10,BAG2,VPS28,MINAR1,SIAH2,CDK5,ANGPT1,GABARAP,FBXW7,ISG15,HUWE1,RPS7,HSP90AA1,PELI1,SQSTM1,MAGEC2,SPOPL,CHP1,MIR101-1,SVBP,UBE3A,SIRT7,TNFAIP3,RCHY1,CTNNB1,UBE2L3,FZR1,PPIA,CDC20,BIRC2,RPS3,CAMLG,UBB |
| 1.049e-03 | -6.86 | negative regulation of inflammatory response | biological process | GO:0050728 | 201 | 80 | 18204 | 5365 |
IER3,MIR145,MIR920,GSTP1,MIR126,TNFAIP6,CCN3,TRIM45,TNFAIP3,YES1,IL13,GPX1,MIR142,MIR15A,PYDC2,GPR17,ADIPOQ,MIR223,MACIR,IGF1,IL10,IL12B,SMAD3,FGR,FCGR2B,MIR590,KLF4,SELENOS,DUSP10,PSMA1,CD200,PPARA,FEM1A,SYK,MIR205,OTULIN,PSMB4,LDLR,FOXP3,SRC,ADORA1,MIR16-1,NFKB1,MIR141,MIRLET7G,MIR195,RB1,NPY5R,MIR488,NLRP6,SOCS3,IL2RA,CD200R1,FURIN,MIR187,MIR181C,TMSB4X,MIR105-1,MIR204,ACP5,PPARG,MIR221,IL2,MIR149,MIR146A,LPCAT3,SOD1,PTGER4,GHRL,MIR20A,IL20RB,SOCS5,TNFRSF1B,MIR222,IL4,MIR31,IL22,NDFIP1,TNFAIP8L2,NLRP3 |
| 1.050e-03 | -6.86 | GOLGB1 (golgin B1) | protein interactions | 2804 | 180 | 70 | 19454 | 5460 |
COX4I2,MSX2,FURIN,TFRC,PDHA1,RAB4A,EWSR1,TMT1A,SAR1B,RAB3B,LAMP3,HDAC6,LAMP2,DPP4,SLC25A46,RAB5C,MARCHF5,RHOG,HSD17B11,GJA1,RAC2,NDUFA1,RAB35,STX6,LMAN1,CAV1,NUP35,CDC5L,HNRNPL,VTI1B,TMED9,RHOH,CDC42,RND2,OTULINL,BORCS6,ATG16L1,CLDN4,BET1,TMOD1,PIH1D1,CAV2,RPA2,HSPA8,SQSTM1,RAB9A,RAB5A,RPA3,SLC2A3,STX7,PXMP2,KDM1A,ADRB2,LPAR1,BRMS1,DNAJC5,TMED5,RAB2A,RAB11A,NRP1,LAMTOR1,DCAF4,TMEM74,PHF21A,UBE2I,ARF1,DYRK1A,VIRMA,ESR2,DYNLL1 |
| 1.051e-03 | -6.86 | ACAA2 (acetyl-CoA acyltransferase 2) | protein interactions | 10449 | 159 | 63 | 19454 | 5460 |
VAMP2,SOD2,HADH,VDAC1,FKBP2,HSPD1,PREPL,HNRNPA2B1,EWSR1,HSD17B10,AK2,TMEM70,UPK1A,PRDX1,TAX1BP3,ERCC3,ISYNA1,HDAC6,YWHAG,HNRNPA1,ATP1B1,DBT,PPIA,SSBP1,H2AZ1,MGME1,TES,CDK1,IDH2,PAFAH1B1,CRAT,HSCB,UCHL3,USP8,NT5C3A,CSRP1,SNRPA,EXD2,HSPB2,PGK1,TERT,RTN4,SPOP,ATP1B3,ACO2,MYC,CIAO1,BTF3,AK3,CFL1,TOMM40,HMOX2,LDHA,GPX1,TAGLN2,LGALS3,ARMC6,VDAC2,ENO1,SF3B4,MSN,SGTA,ACAT1 |
| 1.051e-03 | -6.86 | TYRO3 (TYRO3 protein tyrosine kinase) | protein interactions | 7301 | 159 | 63 | 19454 | 5460 |
RAB1B,COCH,HSP90AB1,HACD3,PTK7,SRPRA,STT3A,DCK,CDCA3,NCR3LG1,HAX1,PTDSS1,PIK3R1,MDFI,PROS1,DDRGK1,CTNNB1,COPS5,XPO1,SRPRB,NDUFA4,SLC25A5,SLC39A7,RPN1,TFRC,STIM1,GNAI3,PLD3,STK16,NEU1,ERLIN2,CTDSP2,YES1,SRC,TECR,CTNNA1,GXYLT1,SEC61A1,CHTOP,ATP1B3,XPOT,ATP1A1,EPHA2,HSP90AA1,GORASP2,SLC1A3,MGAT5B,CNNM4,LPAR1,RNF41,CLU,HSPA5,PIP4P1,TMEM106B,ITM2B,DNAJC3,SSR1,ATP5PO,CTDSP1,SLC25A3,MET,USP6NL,NTPCR |
| 1.052e-03 | -6.86 | MED20 (mediator complex subunit 20) | protein interactions | 9477 | 177 | 69 | 19454 | 5460 |
THRAP3,VDAC1,HUWE1,SNRPG,ARF4,PDIA6,GABPB1,UCK2,PSORS1C2,CDK8,RAD23B,BIRC5,POLR2D,POLR2C,POLR2G,MED9,ATP5PB,RAF1,EXOSC8,SMAD1,RPAP2,DDX39A,SPTAN1,POLR2I,RPS10,POLR2L,PHB1,THOC2,GATD3,AKR1B1,CORO1C,PSMD10,MED29,MED21,GSTO1,MED27,MED4,PHB2,FBXW7,TRA2B,MED11,TCEA1,EP300,MED13L,ATP5IF1,MED23,FKBP1A,MED31,ATG16L1,CNP,MED30,FBXL19,MED17,ESR2,POLR2B,UBB,GNG12,GNPDA1,GTF2F1,ALB,POLR2F,MED10,MDH1,POLR1B,SERPINH1,SMAD2,MED22,LMO2,AR |
| 1.053e-03 | -6.86 | RFC2 (replication factor C subunit 2) | protein interactions | 5982 | 162 | 64 | 19454 | 5460 |
DDRGK1,COPS5,WWP2,HMGA1,IFI16,BRD3,DDX1,SNRNP70,H2AC4,PHB1,SSBP1,CDC5L,SUMO2,RPS16,CAND1,SPPL3,FZR1,SOX2,E2F4,RAF1,NUPR1,RAD1,RAD23B,HGS,PSMC3,EZH2,RTCB,PCNA,MDC1,RFC3,SSRP1,H3C1,PSMA1,KRAS,RFC5,CUL3,VAMP5,MYC,RIT1,UBE2H,EXOSC1,BRCA1,GTF2F1,RTRAF,ZNF330,IRF2,CCNF,RPL10,ESR2,APEX1,TRIM29,CFTR,SETD3,CCND1,SYK,RPA2,LMNA,EP300,RPA3,RFC4,DVL2,BAP1,GINS3,HSCB |
| 1.053e-03 | -6.86 | WEE2-AS1 (WEE2 antisense RNA 1) | protein interactions | 285962 | 162 | 64 | 19454 | 5460 |
GTPBP1,DOHH,TUBB4B,MINDY3,EEF1A1,EGR2,RAF1,MSH6,RIGI,CTNND1,THRAP3,CLPB,TRIM21,SLC25A11,HNRNPA2B1,PABPC1,ALKBH4,NEK9,HSPB1,HAX1,DDX1,RPS2,DDX23,GAPDH,HMGA1,HSP90AB1,TMPO,KCTD3,RPLP2,PSMB1,LDLR,MAGED2,AGAP1,PALS2,RPRD1B,MED23,QTRT2,TANK,TOR1AIP2,FXR2,RAB5A,SQSTM1,HSPA8,HNRNPH2,RPS28,RETREG2,HSP90AA1,IGF2BP1,RPS29,HMGCS1,RPS17,PSMD1,SEC13,HNRNPC,GRB10,NCKAP1,ERH,UBB,NDFIP1,ALB,CALML5,DLST,TUBA1B,GAB1 |
| 1.053e-03 | -6.86 | TUBGCP2 (tubulin gamma complex component 2) | protein interactions | 10844 | 162 | 64 | 19454 | 5460 |
TMEM126A,TP53,CD2BP2,TUBA1A,EEF1A1,TUBB4B,VPS33A,PPP4C,UQCC2,METTL18,RUSF1,EFNB1,BAG2,SAV1,WWP2,XPO1,COPS5,P2RY10,MZT2B,TUBG1,HAX1,SSR2,SPINT2,RPLP2,SPPL3,PRNP,CGAS,EGLN3,SRSF10,CDC5L,LRWD1,HSP90AB1,ATG16L1,NPY2R,RND2,RPA2,RARS1,RPA3,PRPF4,HSPA8,HSPA5,MYC,GPR17,OPRM1,CUL3,PHKA1,FBXW11,IGF2BP1,RIT1,LMBR1L,RPS3,CCNF,TUBA1B,CHRM4,ANAPC2,RPS20,ACTB,TUBB,TXNDC12,APLNR,UBB,APEX1,VIRMA,ESR2 |
| 1.054e-03 | -6.86 | ILVBL (ilvB acetolactate synthase like) | protein interactions | 10994 | 174 | 68 | 19454 | 5460 |
GHITM,PICALM,RPA2,CYC1,SLC25A3,CDC42,ADRB2,CYFIP2,HSCB,NCDN,RPA3,DERL1,RNF113A,HSPA8,ATP1A3,ILK,NRP1,XPOT,NTRK3,HNRNPC,CIAO1,CUL3,MYC,RHOBTB3,NCAPG2,RPGRIP1L,RAB14,COPE,TNPO3,VIRMA,UQCRQ,DPEP1,LMBR1L,OPTN,VDAC2,CCNF,ACAT1,ODR4,INTS12,NDUFS3,MOB3C,UBL4A,ZMYM4,FAF2,TOM1,RIGI,FLOT1,SLC6A8,OSTM1,RAB1A,TESK2,SKA1,PICK1,RB1CC1,ADIPOR2,ATP5MG,MAPK4,NFKB1,ATP1B1,EIF2B5,ARF6,MSMO1,SRSF1,FBXO32,SDHB,PTPN1,COQ8A,XPO5 |
| 1.055e-03 | -6.85 | RBM15 (RNA binding motif protein 15) | protein interactions | 64783 | 165 | 65 | 19454 | 5460 |
SOS2,FGD2,SSRP1,RIGI,TOP3B,RAF1,TP53,E2F4,SOX2,NUPR1,FURIN,SRP14,ALYREF,EED,RAC2,FZR1,TOP1,DHX15,WIF1,IFI16,DPP4,YWHAH,YWHAG,HNRNPA1,DDRGK1,DDX23,SNRNP70,PEX3,RPA3,DDX39B,SNRPA,SIRT7,SF3B1,CLK1,EP300,UFL1,HDAC3,PFKFB2,STAU1,COIL,TOR1AIP2,RPA2,MED23,WTAP,CCNF,CTTN,FGFBP1,CTSB,FBXO22,SNRNP40,RHOJ,RPGRIP1L,SRPK2,VIRMA,MYC,RRN3,RNF40,DEPDC1B,PPP1CC,RBM15B,RC3H2,YWHAZ,NCKIPSD,RIT1,THTPA |
| 1.055e-03 | -6.85 | NKX2-1 (NK2 homeobox 1) | protein interactions | 7080 | 171 | 67 | 19454 | 5460 |
CALR,HMGA1,IFI16,GAPDH,TOP1,CGAS,MYL12A,TMPO,SRSF10,NUP35,CBFB,ETV6,SSBP1,ALYREF,PHB1,TFCP2,ILF2,MTA2,APTX,PSMC3,NUP37,NUP107,THRAP3,CSE1L,RUVBL1,RFC2,RFC3,POLDIP3,SSRP1,MDC1,PSME1,HAPSTR1,PCNA,RUVBL2,CCT2,MECP2,H2AZ2,LMNB1,CREBBP,SMARCA5,SEC13,RFC5,RUNX1,NONO,IRF2BP1,RBBP4,JUNB,LIG3,RAN,PARP2,RTRAF,MACROH2A1,UBE2I,CTBP1,ATP5PO,LMNA,RPA2,IRF2BPL,SLC25A3,NUP62,TRA2B,KDM1A,TMEM209,RFC4,RPA3,XRCC5,BANF1 |
| 1.055e-03 | -6.85 | EIF4G2 (eukaryotic translation initiation factor 4 gamma 2) | protein interactions | 1982 | 168 | 66 | 19454 | 5460 |
EMG1,HSPA8,PGK1,PML,RPA3,MARS1,HSPA5,EIF4E,OXCT1,TANK,ACTL6A,ATG16L1,EIF4B,MFAP1,RPA2,RPS20,EIF2S2,METAP2,CCNF,LMBR1L,RPL10,ESR2,MAD2L1,EIF4A2,EIF4H,DNAJC8,GGH,PYCR2,MYC,CREBBP,DNAJB6,MAPRE1,OAT,RC3H2,CYP1A1,BAG2,RPL3,RINT1,POLDIP3,CDC40,G3BP1,KRAS,TRAF2,RPSA,NDUFA2,YTHDF2,CENPM,TAF2,RNF126,MOB3C,PNMA2,EEF1AKMT3,MDM2,CDK9,PRNP,SUMO2,RPL35A,DCUN1D1,FZR1,CSNK2A1,XPO1,WWP2,RBM17,KARS1,CENPP,HSPB1 |
| 1.055e-03 | -6.85 | ASNS (asparagine synthetase (glutamine-hydrolyzing)) | protein interactions | 440 | 168 | 66 | 19454 | 5460 |
NTRK3,UBE2H,RHOB,STK24,ATG101,GALE,UFD1,AR,MAT2A,MYC,RPL7A,CUL3,FAM78A,NDN,MSN,IRF2,CCNF,FAIM,LMBR1L,HEXIM1,SHOC2,RPA2,ISOC1,CD2AP,NEK7,DUSP22,ATG16L1,PAFAH1B1,RNF11,UFL1,STAU1,HSPA8,NUP50,EP300,STK26,SQSTM1,SOD1,RPA3,PEBP1,BAP1,SIRT7,AHSA1,DNAJC7,COPS5,SNAP91,DDRGK1,GLRX,CDK9,DNAJC1,DCUN1D1,SUMO2,TES,FBXO32,POLR2C,CAPN2,OTULIN,GFPT1,MSX2,LYPLA1,OLA1,SAR1B,XPNPEP1,PICK1,SCPEP1,ABCE1,TRIP4 |
| 1.057e-03 | -6.85 | positive regulation of amyloid-beta formation | biological process | GO:1902004 | 20 | 13 | 18204 | 5365 |
GSK3A,CSNK1E,SP1,CHRNA7,LRRTM3,IFNGR1,PICALM,TNF,CLU,ROCK2,IFNG,EPHA4,MIR206 |
| 1.057e-03 | -6.85 | protein import into mitochondrial matrix | biological process | GO:0030150 | 20 | 13 | 18204 | 5365 |
GRPEL2,TOMM20,ROMO1,TIMM23,DNAJC19,DNLZ,TOMM7,TIMM21,TOMM70,TOMM40L,TOMM40,GRPEL1,TIMM17A |
| 1.057e-03 | -6.85 | regulation of vesicle size | biological process | GO:0097494 | 20 | 13 | 18204 | 5365 |
RAB22A,BORCS8,RAB5A,KXD1,BLOC1S2,RAB3B,BORCS6,RAB11A,AP2M1,PICALM,BORCS5,BORCS7,SNAPIN |
| 1.057e-03 | -6.85 | negative regulation of release of cytochrome c from mitochondria | biological process | GO:0090201 | 20 | 13 | 18204 | 5365 |
FXN,BAK1,GHITM,PPIF,GPX1,PARL,CLU,BCL2L1,LMNA,PSMD10,IGF1,PRELID1,AKT1 |
| 1.058e-03 | -6.85 | cervix-carcinoma | COSMIC cancer mutations | cervix-carcinoma | 42 | 22 | 16828 | 4835 |
IDH1,KRAS,HRAS,NFE2L2,SF3B1,RUNX1,STK11,FBXW7,CDKN2C,AKT1,JAK2,SRSF2,TP53,CTNNB1,MET,RB1,KIT,DICER1,PTEN,SMARCB1,PIK3CA,FGFR1 |
| 1.059e-03 | -6.85 | AQP3 (aquaporin 3 (Gill blood group)) | protein interactions | 360 | 238 | 89 | 19454 | 5460 |
ICAM1,FIS1,ABHD12,STAT1,TUBB,LGALS3,GPR89A,FAM91A1,SLC25A3,LMBRD2,DHRS4,TIMM29,TOMM22,PXMP2,CYFIP2,TMEM177,ATAD1,RER1,BMPR1A,HAX1,STX1A,PEX3,NDUFB8,ITPRIPL2,XPO1,FAM241A,WDR11,SEC61A2,ECHDC1,XPO5,NDUFA12,AQP3,TUBA1A,CYB5R1,TNPO2,LYPLA1,PGAP4,ZNF609,TNF,SLC25A23,NDUFB5,GGCX,DNAJC19,MGST3,ARMC6,SLC25A4,CYBC1,PTPMT1,SLC1A1,SCAMP2,SMAP2,PIGW,LMNA,SAMM50,STX17,SLC35E1,PLP2,COQ8B,SLC35F6,TIMMDC1,ADIPOR1,TMEM209,ORMDL1,RAB29,TMEM263,FITM2,TMEM42,TMEM107,ORMDL3,TSPO,SLC25A46,SLC25A17,MSMO1,CAV1,VTI1B,DNAJC1,SLC39A10,SRPRA,SSMEM1,SLC25A24,DHRS7B,GPD2,DDX39A,AGPAT5,FASTKD5,LPCAT3,CSE1L,ERG28,RUSF1 |
| 1.060e-03 | -6.85 | ovary-low_malignant_potential_(borderline)_tumour-mucinous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-mucinous | 37 | 20 | 16828 | 4835 |
PIK3R1,IDH1,KRAS,SMAD4,SF3B1,IDH2,FBXW7,PPP2R1A,JAK2,AKT1,BRCA1,SRSF2,TP53,MET,KIT,CTNNB1,DICER1,PTEN,PIK3CA,FGFR1 |
| 1.068e-03 | -6.84 | COPS8 (COP9 signalosome subunit 8) | protein interactions | 10920 | 112 | 47 | 19454 | 5460 |
UBE2M,WDR77,FBXO42,DET1,SKP1,HSPA5,BAP1,FBXW4,APPBP2,DDIT3,DCAF4,NCKIPSD,DTL,STK11,COP1,MAPRE1,COPS7A,CUL3,CUL2,ATP5F1A,PRPF31,FBXO7,FBXO22,DYNLL1,UBB,NFKBIA,RHOBTB1,E2F4,TP53,MAP1LC3B,NEDD8,KRAS,CRYBA4,COPS4,EIF3E,FBXO11,HSD17B10,CRBN,DCAF11,DCAF4L2,COPS5,CTNNB1,FEM1B,DCUN1D1,COPS7B,HSP90AB1,COPS2 |
| 1.068e-03 | -6.84 | DTL (denticleless E3 ubiquitin protein ligase homolog) | protein interactions | 51514 | 112 | 47 | 19454 | 5460 |
YWHAG,COPS5,YWHAH,UBE2E2,YWHAB,MGMT,TUBG1,UBE2D1,COPS2,SRSF1,UBE2N,CCT7,MDM2,SHPRH,TCP1,CCT5,TP53,PCNA,FBXO11,MSH6,COPS4,PFDN1,KRAS,SFN,CUL3,COPS7A,RIT1,PDCD4,PFDN2,POLD4,YWHAZ,UBE2E3,CCT2,UBE2I,LMBR1L,LORICRIN,CCNF,BUB3,TCEAL1,CCNA2,CDKN1A,CFTR,UBE2M,SAMM50,CDK1,FBXW7,SLC31A1 |
| 1.077e-03 | -6.83 | GLUTPROXDASE | prints domains | PR01011 | 8 | 7 | 5227 | 1528 |
GPX4,GPX3,GPX6,GPX2,GPX7,GPX5,GPX1 |
| 1.077e-03 | -6.83 | SYNAPTOBREVN | prints domains | PR00219 | 8 | 7 | 5227 | 1528 |
SEC22B,VAMP3,VAMP8,VAMP7,VAMP5,VAMP1,VAMP2 |
| 1.080e-03 | -6.83 | HDAC3 (histone deacetylase 3) | protein interactions | 8841 | 294 | 107 | 19454 | 5460 |
PPAT,SRC,CCNF,ZBTB33,NR2E1,F9,TXNIP,CREB3,AKT1,RUNX1,GMNN,NONO,AR,GTF2I,HDAC3,KDM1A,MEF2A,BCL6,RPA3,IRF3,PML,SAMM50,ACACA,BRINP1,CCND1,CXCL8,MDM2,TMPO,ETV6,RB1,LDLR,TNFRSF14,NFKB1,CSNK2A1,SUV39H1,ZSCAN5A,H3C1,PIWIL2,IGF1R,NFE2L2,TAB2,PPP4C,SAP30L,TP53,CCT5,ZMYM3,STAT1,RBBP4,ESR2,APEX1,CRYBB3,NFKBIA,ZMYM2,CCT2,SP1,MYC,CREBBP,PAPOLA,PROX1,THAP7,BRMS1,PHB2,ZBTB5,TNFSF10,HSPA8,SF3B1,HDAC5,EP300,DDX5,PPARG,CTBP1,GTF2IRD1,H2AC1,SYK,CNPY3,PGR,TCP1,CCAR2,EGLN3,ANKRA2,CCT7,CBFB,EED,TRAF6,CNOT2,PIK3R1,HR,INSYN1,XPO1,SIAH2,ZBTB16,OVOL1,TOP2B,CCT8,ATF3,PRDM4,EWSR1,BAG2,EZH2,H2BC1,E2F4,SUPT5H,ZNF704,SOX2,JUN,TUBA1A,SAP30 |
| 1.083e-03 | -6.83 | GPX_CS | interpro domains | IPR029760 | 8 | 7 | 18521 | 5414 |
GPX3,GPX4,GPX5,GPX2,GPX7,GPX1,GPX6 |
| 1.083e-03 | -6.83 | Glutathione_peroxidase | interpro domains | IPR000889 | 8 | 7 | 18521 | 5414 |
GPX3,GPX7,GPX2,GPX5,GPX4,GPX6,GPX1 |
| 1.083e-03 | -6.83 | Synaptobrevin-like | interpro domains | IPR001388 | 8 | 7 | 18521 | 5414 |
VAMP5,VAMP8,VAMP3,VAMP2,VAMP7,VAMP1,SEC22B |
| 1.084e-03 | -6.83 | FNTA (farnesyltransferase, CAAX box, subunit alpha) | protein interactions | 2339 | 92 | 40 | 19454 | 5460 |
FNTB,CFTR,RPL15,CDC42,PPIF,DDX39A,CAPN1,PAFAH1B1,ARFGAP1,RPL18,PGGT1B,CAPN2,ACVR1,PTP4A2,VAV2,SNX33,RPL23A,BAP1,ATG4A,KRAS,YKT6,CHCHD2,GTF2I,RNF40,HDAC6,RIOX2,GRSF1,RIT1,CBL,RHOB,BRCA1,HRAS,TNIK,DYRK1A,PTP4A3,PRNP,TOP1,RPL13A,STAT2,TP53TG5 |
| 1.084e-03 | -6.83 | ZHX1 (zinc fingers and homeoboxes 1) | protein interactions | 11244 | 92 | 40 | 19454 | 5460 |
LYAR,SUMO2,DYNLL1,RBBP4,PNP,ELK3,DLST,PAFAH1B3,CREB1,ZHX3,UBE2I,ZHX1,CSNK2B,BRCA1,PIGC,MPHOSPH6,BCL2L1,CREBBP,NFYA,AKT1,ZMYND11,CSNK2A1,GNG11,TOLLIP,HSPE1,ZBED1,RBBP7,PAX6,GADD45A,BHLHE40,ZYX,DDX39B,IDH1,SAT1,KLF3,SUMO1,TP53,SERPINB9,WDR83,KLF12 |
| 1.084e-03 | -6.83 | MLEC (malectin) | protein interactions | 9761 | 92 | 40 | 19454 | 5460 |
OST4,CTSD,FAM241A,TIA1,COPS5,AGR2,CALU,TSNAX,RB1CC1,CYB5R3,DLST,CCNF,STT3A,CYB5A,SEC61B,SLC25A4,RPS16,ESR2,VIRMA,PGRMC1,CCDC47,CDK7,DNAJC25,PICALM,RPN1,RPA2,HECTD1,CYB5B,SCLT1,TMEM106B,DNAJC3,RPA3,AKAP1,DNAJC30,TOLLIP,VDAC1,HSCB,PSEN1,DAD1,TUSC3 |
| 1.084e-03 | -6.83 | IST1 (IST1 factor associated with ESCRT-III) | protein interactions | 9798 | 92 | 40 | 19454 | 5460 |
BICD2,VPS4A,RIT1,CSK,FAM20C,WWP2,RAB5C,BTF3,BTF3L4,FZR1,CGAS,PRNP,CHMP5,FUNDC2,CDC20,ATP6AP2,ESR2,CCNF,HEY2,ANAPC2,AP1G2,VPS4B,CHMP1A,ISOC1,HGS,NUPR1,APEH,PTAR1,ISG15,TIMM13,KRAS,CHMP1B,NF2,USP8,VTA1,RIGI,HSPA5,TFG,NSDHL,HNRNPA2B1 |
| 1.086e-03 | -6.83 | negative regulation of ion transmembrane transporter activity | biological process | GO:0032413 | 72 | 34 | 18204 | 5365 |
ATP1A2,DRD3,MIR153-1,OXSR1,HECW1,MIR212,MIR208B,CAB39,GSTM2,GSTO1,MIR208A,TLR9,MIR30D,PLN,SUMO1,MIR448,MMP9,GPR35,SRI,CRHR1,CAV3,FKBP1B,MIR1-1,TCAF2,PRKCE,MIR24-1,MIR192,PCSK9,MIR200C,CAV1,EPO,FKBP1A,KCNAB1,CLIC2 |
| 1.093e-03 | -6.82 | SMAD7 (SMAD family member 7) | protein interactions | 4092 | 115 | 48 | 19454 | 5460 |
SMURF1,UBE2L3,TAB1,SETD7,CXXC5,SMAD2,DCAF16,MYC,AKT1,PIAS1,TGFB1I1,HDAC3,RLIM,EP300,HDAC5,HERC3,BMPR1A,FKBP1A,STAMBP,WWP1,SASH3,MAP2K6,SMAD3,USP15,STAMBPL1,SMAD9,CBL,KDM2A,PSMG2,SMAD4,CTNNB1,COPS5,HDAC6,USP2,WWP2,BMPR1B,OVOL1,ACVR1B,TRIM37,TOLLIP,TGFBR2,TAB2,ACVR1,BMPR2,SMAD1,MAP2K3,TP53,TOP3B |
| 1.093e-03 | -6.82 | CXADR (CXADR Ig-like cell adhesion molecule) | protein interactions | 1525 | 357 | 127 | 19454 | 5460 |
MAP3K21,RAB11A,PKP4,VEZT,NIBAN2,SCFD1,LMNB1,RHOB,LAMTOR1,CKB,LRRC1,FAM83B,ARF1,MB21D2,RND2,OTULINL,NOTCH2,LNX2,USP6NL,CLDN4,H1-5,FAM3C,VAPB,RAB5A,TMEM185A,STX7,PSMC1,EMC1,DDRGK1,PPFIBP1,XPO1,RAB5C,PIK3R1,UBXN6,LAMP2,DRG1,RASSF8,RHOG,CDK5RAP3,CYB5A,STX5,GJA1,RAB35,WDR6,TNIK,DIRAS3,RHOH,TULP3,FAF2,MACO1,STBD1,RND3,RAB4A,STIM1,VAMP2,EFNB1,EWSR1,TMEM87A,SAR1B,FLOT1,JAML,KRAS,GORASP2,DNAJC5,HMOX2,DEPDC1B,RAB2A,ATP1A1,EPHA2,NECTIN2,STUB1,GAB1,VAMP3,SEC63,FERMT2,SH3BP4,RHOJ,YES1,CNP,CDC42,SEC22B,ARHGAP1,PIP5K1A,UBA52,ATG16L1,RABL3,LEMD3,SLC12A2,RAB9A,TEX264,RHOU,RPA3,PIK3R2,FTSJ1,NF2,YKT6,LAMP3,TMEM199,RELL1,OSBPL8,ESYT1,RAC2,CDCA3,ADD1,CAMLG,EHBP1,SRPRA,HRAS,PTPN1,CAV1,STX6,SLC38A2,LMAN1,ARF6,ANKRD46,CCDC47,PREB,SNAP29,SHISA2,SNAP23,DLG1,NSDHL,PALM2AKAP2,ADD2,SLC6A8,CTNND1,RAB3B |
| 1.097e-03 | -6.82 | GLYR1 (glyoxylate reductase 1 homolog) | protein interactions | 84656 | 229 | 86 | 19454 | 5460 |
RPL4,FBXW7,NOP53,STAU1,DGCR8,KDM1A,NPM3,UFL1,UTP23,SIRT7,RPA3,LCP1,LARP4B,MACROH2A2,HECTD1,RPLP0,H1-5,RPL35,RPL13A,APEX1,RPL19,ESR2,SRPK2,ZNF330,RPS9,FGFBP1,RPL37A,PRKRA,RC3H2,ZCRB1,SPOP,H1-1,UBE2H,CDKN2D,RPL7A,MYC,RPL26,ZNF668,HMGN4,H3C1,RPL17,PAX6,SRSF4,RPL28,MEPCE,PPAN,TOP2B,EIF1AD,RPL31,SRSF7,DHX9,RPL23A,RPL3,RBM34,DISC1,RNF181,ILF2,HBP1,RPSA,ZNF263,RAF1,FNTB,H1-3,SOX2,LYAR,HNRNPL,RPS10,RPS16,NOP58,ZBTB2,SURF6,STK3,NTMT1,KRR1,SRSF1,SRP14,RPL8,EED,H2AC4,RPL10A,LHX2,RPS2,MED4,PLEKHO1,IFI16,DDRGK1 |
| 1.097e-03 | -6.82 | LUC7L (LUC7 like) | protein interactions | 55692 | 229 | 86 | 19454 | 5460 |
LSM14B,NLRP3,H1-1,RBM27,MTG2,AUH,RPL10,KBTBD6,ESR2,PRRC2A,TNPO3,GADD45G,SNRPD2,PRMT5,SNRPD1,DLST,NEK7,ZC3H14,CMAS,FTL,EP300,HSPA8,EXD2,SNRPA,DDRGK1,TRA2A,XPO1,YWHAG,WWP2,IFI16,PRDX1,DDX50,SRSF10,SNRPD3,HNRNPL,RPS10,GATD3,PHB1,SRSF1,FOLR1,ZRANB2,CHMP4C,PDHA1,NFKBIL1,RAF1,CHCHD2,G3BP1,SRSF8,SRSF7,RPL31,UBE2H,CASC3,PPIG,RBM7,RC3H2,RPL7A,SRPK2,RNASEH1,FGFBP1,CSNK2B,CCNF,LUC7L3,MTRES1,RPLP0,H2AB1,FBXW7,RPL4,DGCR8,RNF113A,RBM23,SNRNP70,H2AC4,CSNK2A1,GRSF1,ZBTB2,CDC5L,NKAP,MRPS9,SYNCRIP,LBR,MRPL11,FBXO25,MEPCE,THRAP3,CTNNBL1,MRPL52 |
| 1.101e-03 | -6.81 | T_SNARE_dom | interpro domains | IPR000727 | 27 | 16 | 18521 | 5414 |
BET1L,STX5,STX7,STX11,STX12,SNAP29,SNAP25,STX1A,STX17,STX10,SNAP23,VTI1B,STX8,STX16,STX6,BET1 |
| 1.101e-03 | -6.81 | Longin-like_dom_sf | interpro domains | IPR011012 | 27 | 16 | 18521 | 5414 |
SEC22C,AP1S2,TRAPPC2L,SEC22A,ARCN1,AP2S1,TRAPPC4,VAMP7,SRPRA,YKT6,COPZ2,TRAPPC1,SEC22B,AP1M1,AP3S2,AP2M1 |
| 1.103e-03 | -6.81 | MARK4 (microtubule affinity regulating kinase 4) | protein interactions | 57787 | 78 | 35 | 19454 | 5460 |
PRNP,TUBB,MANSC1,APLNR,PPP2CB,KCTD20,PNMA1,YWHAZ,TUBG1,NLRP3,YWHAB,DRG1,MAP4,STK11,PYCARD,AKT1,YWHAH,YWHAG,HNRNPK,RPIA,SLC31A1,CYFIP2,PTGES3,RNF41,FTL,HAPSTR1,PNMA2,HPS6,PSMC3,HGS,PARD6A,TOP3B,PPP2R1A,CDC42,TUBA1A |
| 1.103e-03 | -6.81 | B2M (beta-2-microglobulin) | protein interactions | 567 | 78 | 35 | 19454 | 5460 |
SAMHD1,CALR,MAP1S,PTTG1,HFE,RHOG,RHOB,RAC2,UBE2I,CD1E,CD274,CHRM4,CD1A,RHOJ,RANGRF,PPAT,OSBP,CDC42,MAP1LC3B,CFTR,LILRB1,PRSS23,TFRC,CRYAB,CLK1,CD1D,TAPBP,HSPB2,CXCR4,MORC2,TMEM106B,B2M,TPST1,TRIM37,CD1B |
| 1.103e-03 | -6.81 | GLOD4 (glyoxalase domain containing 4) | protein interactions | 51031 | 78 | 35 | 19454 | 5460 |
HSPD1,MYD88,SOD1,HSPA8,HINT2,SAR1B,FKBP2,PPIL3,DDAH1,MAX,CMPK1,FEN1,PGM1,SOX2,NDUFAB1,GLRX5,NECAP2,EZH2,PIH1D1,ARCN1,SCLT1,NUDT9,WDR82,TENT5C,SNX3,PRDX2,TXN,GMPPB,ACO2,GLO1,GAPDH,BCL2L1,HSPB1,UBE2H,FKBP1B |
| 1.106e-03 | -6.81 | regulation of monoatomic ion transmembrane transport | biological process | GO:0034765 | 347 | 129 | 18204 | 5365 |
CFTR,SCN2B,PLN,G6PD,KCNJ3,ATP1B1,CCR2,F2,ATP1A2,SLC8A1,PPIF,DLG1,ATP2B4,MIR200C,PPP3R2,CXCL10,NHERF1,VAMP2,NPSR1,FKBP1A,CCL2,KCNS1,JPH4,SPHK2,TMSB4X,ACTN4,PML,SLMAP,PCSK9,ASIC2,PRKCE,CACNB4,DRD1,KCNJ8,KCNIP2,MIR448,PLP1,SUMO1,FGF13,CRHR1,SRI,RANGRF,MIR30D,PPP3CA,GSTM2,TMBIM6,TESC,MIR208B,CAB39,HECW1,ADRB2,DRD3,CX3CL1,ABCB1,CACNB3,MIR24-1,CHP1,ISCU,KCNJ10,SCN3B,XCL1,MIR192,CD63,TCAF2,BAK1,VMP1,CXCL11,KCNMB1,LACRT,TLR9,NOS1AP,MIR208A,KCNIP3,AMIGO1,GSTO1,OPRK1,SELENON,STIM1,MIR212,MIR21,STOM,MIR153-1,COX17,EPO,CLIC2,KCNAB1,CAV1,EDNRA,MIR210,FKBP1B,NDUFA4,FXYD6,GPR35,UBASH3B,CAV3,KCNJ2,KCNJ11,YWHAH,TMEM38B,STAC3,VDAC1,TRPC1,PSEN2,OXSR1,NETO1,HOMER1,SNTA1,PRNP,PHB2,CRBN,PDE4B,PIK3CG,THY1,APLNR,FGF12,KCNC1,CACNB2,CXCL9,DPP10,WWP2,IFNG,ATP1B3,SCN1B,BAX,HPCA,MIR1-1,SESTD1,MMP9,IL13 |
| 1.106e-03 | -6.81 | NUFIP2 (nuclear FMR1 interacting protein 2) | protein interactions | 57532 | 392 | 138 | 19454 | 5460 |
MIR106B,MIR25,NELL2,TSC22D3,TOP1,MIRLET7G,FZR1,RPS16,CDK9,RBM42,GAPDH,COPS5,PPIL4,MIR34A,SNIP1,RPL23A,TRIM63,MIRLET7C,VWF,MEPCE,YTHDF2,RPSA,TP53,KBTBD4,MIR200C,MAP1LC3B,MIR17,DDX42,SRP72,NUPR1,TAF2,METAP2,CTTN,FBLN5,PSPC1,CCNF,RPS20,RTRAF,NDN,TRAF1,PPP1R10,CYP21A2,NONO,DNAJC5,ZNHIT3,RC3H2,EIF3G,SPOP,MECP2,CASC3,UBE2H,SIRT7,MIR205,PML,BAP1,RPA3,EGFL7,RNF113A,MIRLET7I,LSM12,MIR7-3,RPL4,MIR107,ATG16L1,MIR34B,RBMS2,FGFR1,WWP1,TOX4,RPA2,MIR7-1,MIR21,HEXIM1,MIR7-2,PHB1,DNM2,RPL8,MIR214,WDR82,TSG101,FAM98A,NDC80,WWP2,MDFI,IFI16,ICOS,YWHAG,MIR31,DRG1,RB1CC1,MED4,MIR1-1,CBL,DDX1,PABPC1,LSM14A,PLSCR1,TRIP4,TRIM11,RTCB,ZC3H7A,FAM76B,CBX7,G3BP1,B3GNT2,RAF1,TOP3B,SOX2,JUN,MOB3C,CRELD1,LMBR1L,DKK3,MIRLET7B,ESR2,RPL19,RPL10,MIRLET7D,HNRNPC,KRTAP4-1,SLC22A17,MYC,RBM15B,MIR98,BRCA1,RCL1,MIR363,STAU1,FXR2,G3BP2,RGS19,PABPC5,SYK,LARP4B,KCTD12,MFAP1,NUFIP2,LACC1 |
| 1.107e-03 | -6.81 | monosaccharide metabolic process | biological process | GO:0005996 | 181 | 73 | 18204 | 5365 |
GALE,PC,INPPL1,FABP5,GAPDH,B4GALT1,SLC25A11,CRY1,FUT9,SLC25A10,AKR1A1,OAS1,BAD,GSTO2,PDHA1,RGN,GHRL,NUDT5,PCK2,TKTL1,GSTO1,SLC25A12,G6PD,FUT8,SLC35A2,GDPGP1,MDH1,LIPA,PGK1,ATP1A2,FBP2,RPIA,PIK3CA,ADIPOQ,TNF,SLC2A1,TP53,CRTC2,FPGT,PGM1,SLC2A3,SLC25A1,G6PC3,SLC23A2,LEPR,BRS3,NPY1R,KCNJ11,CHST1,PGM2L1,GCLC,AKT2,KBTBD2,SDS,PMM2,FUT1,ERRFI1,DLAT,AKT1,SLC37A4,PGAM1,ENO1,FBP1,ATF3,AKR1B1,PDHB,LEP,PFKFB2,FKRP,SORD,ATF4,ENO2,PPARA |
| 1.109e-03 | -6.80 | RYBP (RING1 and YY1 binding protein) | protein interactions | 23429 | 226 | 85 | 19454 | 5460 |
HSPB1,RB1CC1,NOS1AP,TUBG1,BTF3L4,ZNF207,POLR3GL,SAT2,CSNK2A1,ATG7,CETN2,MDM2,AGK,OSBP,KCTD3,POLR3F,PSMB1,EED,POLR2L,H2AZ1,RNF8,PHC1,GABPB1,CBX3,EZH2,RAP1A,MTCH2,E2F4,ETFB,TP53,MAX,PCGF6,PAX6,SOCS2,HNRNPK,ROCK2,SRPRB,VRK1,PCGF3,FHL3,UBE3A,TRIM21,POC1B,RING1,SFXN1,LSM14A,PPP1R12A,SCYL2,DNAJB6,ATG3,FTSJ3,TFDP2,MLF2,HNF1B,CEP97,GNB1,ESR2,NMI,SCML2,MORC4,RBBP4,PYGM,RALA,POLR3H,PTEN,POLR2F,POLR3B,CSNK2B,UQCRC2,MRPL53,CYC1,RARS1,E2F6,KLF3,MXD1,ZSCAN1,KLF12,POLR1D,AGTRAP,SKP1,DDX5,PCGF2,YAF2,HSPA8,BTBD10 |
| 1.114e-03 | -6.80 | GSHPx | pfam domains | PF00255 | 8 | 7 | 17795 | 5224 |
GPX7,GPX2,GPX3,GPX1,GPX4,GPX6,GPX5 |
| 1.116e-03 | -6.80 | DNAAF10 (dynein axonemal assembly factor 10) | protein interactions | 116143 | 118 | 49 | 19454 | 5460 |
PTGES3,PDRG1,S100A10,RUVBL1,DNAAF10,THG1L,RUVBL2,RPAP3,CCT8,POLR2D,POLR2G,POLR2C,EXOSC8,RPAP2,CCT5,CCT7,EGLN3,TCP1,POLR2I,SPPL3,POLR2L,RPRD1A,ASB7,ECD,WDR12,ATG7,XPO1,WWP2,POLR1H,BAP1,CSNK1A1,PIH1D1,PARD6A,SAMM50,RPRD1B,POLR1D,PPP1CB,POLR2B,POLR3H,POLR2F,CTU1,POLR3B,PFDN6,POLR1B,PFDN2,PSKH1,CCT2,PPP1CC,SEC13 |
| 1.116e-03 | -6.80 | HARS1 (histidyl-tRNA synthetase 1) | protein interactions | 3035 | 118 | 49 | 19454 | 5460 |
DHRS11,AGR2,KARS1,MOV10,GTF2E1,COPS5,G6PD,TNIK,EEF1B2,SYNCRIP,PHB1,XPO5,PLS3,CHMP4C,DTD1,RAF1,FEN1,TRAF2,EEF1A1,SOX2,MSX2,HNRNPF,KRAS,PFDN1,EIF2D,RAB1A,THG1L,ATG3,YWHAZ,SERPINH1,UBE2H,RIT1,CALU,MYC,DYNLL1,CCNF,PSMC5,RPA2,PCLAF,RARS1,SHMT1,EEF1G,MARS1,RPA3,BAP1,THUMPD1,HSPA8,NUP50,TTC1 |
| 1.116e-03 | -6.80 | POLA1 (DNA polymerase alpha 1, catalytic subunit) | protein interactions | 5422 | 118 | 49 | 19454 | 5460 |
TOP1,PRNP,SUMO2,POLE3,HSP90AB1,WDR6,PSMB1,LDLR,RB1,MOV10,ATG7,BTF3L4,KRAS,H3C1,POLE4,SSRP1,PCNA,CDK8,GINS4,EXOSC3,TP53,SERPINA3,SNRNP40,MAD2L1,VIRMA,ENO1,POLR3H,STN1,DCAF4,MYC,CIAO1,CCNB1,RFC5,BTF3,ISCA2,MCM3,STAU1,POLA2,DDX46,RFC4,RPA3,PRIM2,XRCC5,SIRT7,POLD2,EMG1,CDK1,RPA2,CCNA2 |
| 1.116e-03 | -6.80 | TTC3 (tetratricopeptide repeat domain 3) | protein interactions | 7267 | 118 | 49 | 19454 | 5460 |
STAU1,FUT8,SPTBN1,STXBP1,MIR7-1,PARD6A,LURAP1,TNFRSF1B,CCNF,ANAPC2,NR1H2,APEX1,VIRMA,ESR2,MORF4L1,CUL3,CSK,DSN1,AKT1,AKT3,FBXO7,UBE2E3,PKNOX1,MDH1,PSME1,AKT2,UBE3A,ZC3H7A,BLOC1S2,JAK1,PAX6,TOP3B,SOX2,KRT8,EIF2B5,SPTAN1,HNRNPL,AKAP17A,ZCCHC10,KRBOX4,RAB5C,PPFIBP1,COPS5,PSMD7,TRAF6,HSPB1,DNAJC7,HAX1,ZDHHC15 |
| 1.121e-03 | -6.79 | TMEM9 (transmembrane protein 9) | protein interactions | 252839 | 223 | 84 | 19454 | 5460 |
RAB5C,TSPO,RHOG,OSBPL8,SLC20A1,C2CD2L,HDHD5,DNM2,PTPN1,STX5,RAC2,C2CD2,HSD17B11,XPO5,NOP9,STX6,CD1A,DUOXA2,TMEM97,FAM118B,ARFGEF1,PGAP2,DSTYK,AGPAT5,CLEC2B,PRKAG1,RPN1,UCKL1,RINT1,TMT1A,RUSF1,JAK1,OPA3,RAB3B,KRAS,EPHA4,TNFSF8,TMEM60,SACM1L,RHOBTB3,PPTC7,ATP1A3,VMP1,GGCX,LMBR1L,ADGRL3,STX10,SLC1A1,SEC61B,LGALS3,SLC25A4,RANBP6,TAMM41,PRDX2,APEX1,ALG5,MAD2L2,SEC22B,ST7,MRPL12,KLRD1,NEK7,SEC62,PPT1,SSR1,FEM1A,GOLGA5,FAM8A1,OXSR1,OGFOD3,RAB29,UGDH,RHOU,CXCR4,DERL1,RAB9A,CYP2C18,CLDN1,SYVN1,OXCT1,LPAR1,UFL1,STX7,ZDHHC17 |
| 1.121e-03 | -6.79 | DHX35 (DEAH-box helicase 35) | protein interactions | 60625 | 67 | 31 | 19454 | 5460 |
SNRNP40,SNRPD3,SNRPB,XPO1,ZCCHC10,CDC16,PRPF19,UBE2H,RIT1,SSX2IP,STK11,KIAA1143,BAG2,ELOF1,NKAPD1,EXD2,RPA3,SNRPG,PTGES3,RPL28,STAU1,TSSC4,H3C1,KRAS,CFTR,SNRPN,WDR83,SNRPE,HSPA13,RPA2,LMNA |
| 1.121e-03 | -6.79 | SV2A (synaptic vesicle glycoprotein 2A) | protein interactions | 9900 | 67 | 31 | 19454 | 5460 |
STX7,PXMP2,RNASEL,SLC25A14,ADRB2,RAB3B,B4GALT7,RAB9A,RAB5A,HELLS,RPN1,RAB4A,TP53,ILVBL,SLC25A17,ADCK1,KCTD10,AP2M1,FAM91A1,CCNF,SELENOT,ACTA2,ELOVL4,LAMTOR1,LGALS8,WDR11,ORMDL3,DNAJC5,ATG9A,SLC25A46,RAB11A |
| 1.121e-03 | -6.79 | SKA1 (spindle and kinetochore associated complex subunit 1) | protein interactions | 220134 | 67 | 31 | 19454 | 5460 |
MED4,CCHCR1,UBE2H,ASCC1,INSYN1,PYCR2,NDC80,ILVBL,EGLN3,GMDS,PSMC5,LHFPL2,CCNF,S100A6,NAP1L5,TRIM36,SKA3,SKA2,SNAPIN,KIF2A,SNAP29,SPC24,PSMC1,FTL,PPP2R2C,FBXW7,WASL,MIS12,BAG2,NUDT5,ZYX |
| 1.121e-03 | -6.79 | JADE1 (jade family PHD finger 1) | protein interactions | 79960 | 67 | 31 | 19454 | 5460 |
RPL23A,UBE3A,MEPCE,PFDN1,CDSN,SSRP1,SMN1,H3C1,G3BP1,RPL29,CFTR,TOP3B,ING5,SUPT5H,GSTP1,CALML5,CSNK2B,ACTA2,TMPO,VIRMA,MEAF6,SPTAN1,RIOK2,HMOX2,CTNNB1,CTSD,AKT1,SFN,HSPB1,UBE2H,H2BC17 |
| 1.121e-03 | -6.79 | EFR3B (EFR3 homolog B) | protein interactions | 22979 | 67 | 31 | 19454 | 5460 |
FGFR1,RAB4A,VPS33A,FCAR,CENPM,CDC42,RND2,KRAS,FLOT1,STX7,RHOU,TMEM185A,RHOB,RHOG,LAMTOR1,EPHA2,RAB11A,CSK,RAB2A,LAMP2,DNAJC5,LAMP3,RHOJ,RHOH,ARF6,CAV1,STX6,DIRAS3,RAB35,S100A6,GJA1 |
| 1.121e-03 | -6.79 | GMPPB (GDP-mannose pyrophosphorylase B) | protein interactions | 29925 | 67 | 31 | 19454 | 5460 |
KRAS,MNAT1,EIF2D,HSPD1,RPA3,HSPA8,JUP,RPA2,LMNA,CSNK1A1,SH3GLB2,RBM12,UBE2V1,EEF1A1,CCS,EIF2B5,RANBP6,HPF1,EGLN3,DNM2,CCNF,WDR82,GLOD4,PNPO,RIT1,OAT,FKBP1B,GMPPB,MTMR12,GMPPA,MYC |
| 1.121e-03 | -6.79 | STX16 (syntaxin 16) | protein interactions | 8675 | 67 | 31 | 19454 | 5460 |
RAC2,STX10,VAMP3,ESR2,EGLN3,STX6,RHOH,STX16,VAMP5,ATG9A,NAPA,SCFD1,STX1A,AGR2,RHOB,RHOG,STX18,RHOU,RPA3,PDE2A,STX7,ZDHHC17,NAPG,DUSP22,CDC42,RND2,BET1,SNAP29,TFRC,PTP4A2,RPA2 |
| 1.124e-03 | -6.79 | regulation of interferon-beta production | biological process | GO:0032648 | 59 | 29 | 18204 | 5365 |
POLR3F,OAS1,TICAM1,RIGI,TLR7,IRF7,MAVS,POLR3B,TLR3,NMI,TIRAP,PPM1B,TOMM70,TLR8,HSP90AA1,PTPN11,IRF3,ISG15,PYCARD,FLOT1,TBK1,TLR4,IFIH1,TLR9,MIR26B,IRF1,DHX9,TLR2,LILRB1 |
| 1.124e-03 | -6.79 | immune response-activating signaling pathway | biological process | GO:0002757 | 302 | 114 | 18204 | 5365 |
TRAF3IP3,OAS1,CGAS,KCNJ8,PRKCB,NFKB1,PRKCE,CACNB4,LACC1,FOSL2,TIRAP,LSM14A,NLRP6,IRF7,TLR7,MAP2K6,CRKL,TMEM126A,LAT2,MAPKAPK3,CTLA4,KLRD1,TBK1,UBE2N,TIFA,TLR5,PAK2,BECN1,TLR10,TICAM2,TRAF6,NLRP3,CD14,TLR2,CD38,CD2AP,LY96,PHB1,YES1,EIF2B3,PIK3AP1,KLRC2,TNFAIP3,FCN2,CLPB,CACNB3,TNF,EP300,NFKBIA,PYCARD,HRAS,CREBBP,STK11,TLR6,NCR3,OTULIN,MBL2,PTPN22,NLRP1,SYK,MOG,MEF2C,EIF2B2,ATAT1,ITK,CD28,NMI,RC3H2,VAV2,IKBKB,MAVS,CLEC6A,RBCK1,TICAM1,RIGI,TYROBP,TLR1,CD247,EIF2B5,PSEN1,LCP2,TLR8,LILRA2,IRAK4,MYD88,SLA2,CD3G,IFIH1,TLR9,CSK,CLEC7A,BAX,SPG21,FCER1G,SPPL3,FGR,TLR3,STOML2,PIK3CA,TLR4,THY1,PDE4B,RNF34,IRF3,PHB2,MICB,BTN2A2,CD274,SRC,FOXP3,BCL10,HSPD1,CD79B,PLPP4 |
| 1.127e-03 | -6.79 | STRIP1 (striatin interacting protein 1) | protein interactions | 85369 | 95 | 41 | 19454 | 5460 |
ENO1,ZNF664,CTTN,TRAF3IP3,PPP2CB,TNIK,EEF1B2,PLP1,PSMC5,RMDN3,DYNLL1,SPTAN1,STK3,ESR2,VIRMA,SLMAP,CTTNBP2NL,MOV10,FGFR1OP2,STK4,ISCA2,ENDOD1,STK24,USP15,DDX1,DCAF11,PDCD10,SIKE1,RAB29,CTTNBP2,STK26,FAM168A,EEF1G,CAMK2G,RGS2,ATG16L1,NAA15,TULP3,SNAI3,PPP2R1A,RPS23 |
| 1.127e-03 | -6.79 | NELFE (negative elongation factor complex member E) | protein interactions | 7936 | 95 | 41 | 19454 | 5460 |
RPA2,LMNA,POLR2C,RAF1,ATG16L1,SUPT5H,RPAP2,PSMA5,PSMA1,FBXW7,STAU1,PYM1,RPA3,PML,ELOF1,SF3B1,EP300,PSMA3,YWHAZ,SNRNP70,YWHAB,MYC,WWP2,YWHAH,YWHAG,AR,POLR2B,PSMB6,NCBP2,SRPK2,VAMP3,S100A6,FABP5,LORICRIN,PSMB4,PSMA6,SRSF1,RSRC1,TRIM27,POLR2F,TNKS |
| 1.127e-03 | -6.79 | SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase) | protein interactions | 23049 | 95 | 41 | 19454 | 5460 |
MOV10,BTF3,TUBG1,SMG9,SMG8,IGF2BP1,HSP90AA1,SMAD9,MAGOH,RIT1,EIF4A3,KRT8,SMUG1,FZR1,SPPL3,EIF4A2,NCBP2,PRRC2A,VIRMA,KBTBD4,YTHDF2,TP53,TUBA1A,NECAP2,SNAPIN,EEF2,RPA2,HSP90B1,HAUS2,RPA3,PABPC1,LSM14A,UPF3B,ZC3H7A,RUVBL2,SQSTM1,SMG5,NPTN,FXR2,KRAS,RUVBL1 |
| 1.131e-03 | -6.79 | endometrioid_carcinoma | COSMIC cancer mutations | endometrioid_carcinoma | 15690 | 4553 | 16828 | 4835 |
ZNF655,TEX19,TRIM62,HNRNPAB,GPR78,SLC15A1,KCTD16,PLEKHF1,ZBTB6,AHSA1,SIAH1,LRP3,STRADB,NCK1,ST8SIA4,USE1,TMEM168,CD200,OR6C4,TMEM198,TRAPPC2L,RFX5,MAT2A,NMRAL1,PHOSPHO2,SCG5,TAF9,MEA1,HMGN4,SCHIP1,COX7B2,CMBL,CDKN1B,UQCRC1,NOC4L,CRHR1,AKR1E2,PRPS1,OLA1,HAS3,BAD,TSPAN3,MGST3,WTAP,PDCD10,SSBP2,GDAP1L1,HERC3,PSMB4,SEMA3C,DOK6,IRF9,HSD17B8,LSM4,CGRRF1,DDX39B,NETO1,PTGER2,CDR2,C9orf72,NAA30,ZMAT3,BRS3,RSL24D1,TRAF1,SKAP2,CLK1,RASSF4,KCTD20,SERPINA3,BIRC5,MFSD3,LDB1,CSRNP3,TRAPPC3,GMDS,WNT2,HAPLN2,EDC3,AANAT,VPS26B,YKT6,ANKH,F2,ARL5B,ESYT1,CAMKV,CYP26A1,GMNN,TMEM87A,RALB,ISG20,NUDT1,PRSS35,FKBP2,UNC45A,TBCEL,CCDC22,KDM1A,NDFIP1,PSMG2,DTL,CTDSPL2,ARL6IP5,CEP70,ABHD2,SNRPA1,SNN,SLC7A11,RETSAT,POPDC3,FZD6,MET,GAL3ST4,ADIPOR1,GFM1,HOXB8,SSH3,CENPM,SEC61G,EMX2,PDE6A,HELT,IMP4,TIMMDC1,UBE2V1,SERPINB9,SNX11,RPLP1,TMEM176B,RPL22,CEBPE,B3GALT4,DLG3,RHOU,ACSS2,IFRD1,PDLIM3,PRSS37,MAP1LC3B,ATF3,RBM5,CTLA4,RANBP1,RHOH,ARHGAP15,ERLIN2,HYAL2,NPBWR1,RPSA,PIK3CG,MAGEA4,STT3A,RRP7A,CCDC126,RBM3,CORO1C,RACGAP1,CHTOP,SYPL1,ZNF343,WBP11,ZNF436,DIO2,STARD7,ACTL6A,GNPAT,FOSL2,ACP2,GPR75,SETD3,TMEM126A,NACC2,CHRM5,EMILIN3,DRD3,MTA3,NAP1L3,CEACAM5,DIS3L,CA14,OSBPL8,CEP57L1,ARHGAP19,TACR1,PDLIM4,THG1L,ERCC3,GABBR1,TIMM13,RPF2,XBP1,GPR34,TBC1D1,MRGPRX1,LIPT2,HPCAL1,OR9I1,TRMT5,BCKDK,MED4,ZCRB1,CYB5B,NAP1L5,SEMA7A,RFC4,LCN1,TLR5,TICAM1,HS3ST3A1,GPM6A,COTL1,PNPO,OR2D3,SOX9,CHST10,KCNG3,AKT2,JMJD8,ITPRIPL2,GAB1,PSMC5,PRSS1,APEX1,ECD,CD59,ETFA,APMAP,PRELID1,PSMG4,AQP3,RIMKLB,DEXI,ALG5,SUGP1,ABCC2,FMO1,STARD5,STAP1,ACTR1B,HTR2A,SMARCB1,GTF3C4,MMP20,REG1A,C1QL2,PLCXD3,TSPYL4,OR4K13,DNM2,SRD5A3,CLRN2,DCAF16,ADD2,SOD2,PCP2,TCTA,TMEM231,TEF,ANKRD10,SCN2B,FBXO31,MAP1B,ZDHHC17,CNOT8,PELI1,PIGK,AMELX,VSTM4,PDCD1LG2,RAB1A,GLO1,WDR12,IAH1,MLN,KLF12,MPP1,PSMD1,BARX2,MED27,RANBP10,SRM,ADH1B,SPDYE4,OR4M1,BMPR1B,HS3ST1,TULP3,PCBP4,MLH3,APOBEC3B,FAM193B,BLVRA,CRYBA4,PITPNA,FOXC2,CRYZ,CDK17,CHMP1B,PSMB10,ART5,TMEM39A,ESD,GPR37,CDKN2D,ATP6V1D,VWF,OR5AN1,CLPX,CLP1,INA,ATG3,CFTR,VPS39,SUPT4H1,MYLIP,SART3,PTPRZ1,IFI16,IZUMO2,ZNF200,TPST1,AGGF1,LCP1,HNRNPH3,GCHFR,GJB1,PRELP,KRT8,CSF2,PCYT1B,CHCHD2,TTLL10,HDAC11,SIGLEC5,ATG16L1,TP53TG5,DIRAS3,DYNLRB2,CKS1B,HBP1,SPAG11B,RPL4,SEC14L5,SUV39H1,RGL1,PRKCB,IRF2BPL,LSM5,DCTN3,HCFC2,PABPC5,SLC25A3,RWDD1,COPE,RBM41,CACNB2,HCFC1R1,RPL28,FIS1,EDEM2,SRP72,DDIT3,SLITRK1,PREP,SHC3,ARFGAP1,PIGC,STK38L,MVD,CYP4F22,PTPN5,UFSP1,TIMM17A,RELL1,SMAD9,RNF182,LIPA,SNRPD1,CCL24,ALCAM,OAZ3,VCPIP1,SLC39A10,BCAS4,HM13,TCEA1,PGAP3,MB21D2,LCN15,CCL11,RXFP2,RAB9A,RPAP3,HINT1,TNPO2,THOC6,PYCR1,SLA2,SDR16C5,IFNAR1,MARCKSL1,STX5,RAB11B,ARL6,CCND3,CSRP1,LEMD3,SPATA4,CMTM7,SLC7A1,CA12,TBC1D16,FMOD,ADRB3,NUP62,SMG5,RNF139,DUS4L,ABCF1,PLP2,DYNLL1,HSDL2,LYPLAL1,OPRL1,UCP2,TMEM106B,UBE2I,MED29,MFAP1,MXD1,SLC41A1,PNRC1,EZH1,ARGLU1,MRPL16,TECR,KRTAP4-1,MAP3K3,FHIT,ARL11,IL21,RPL19,ZNF362,MSN,FGF16,HBM,POU5F1,RNASE4,SAP30,DDIT4L,SLITRK5,DICER1,MAGEB1,SLC6A7,SERINC1,SNRNP70,PLEKHF2,GLIPR2,TDP1,MID1IP1,RIT2,CACNG3,IFNA13,EFNA5,ASPM,ZC3H14,CETN2,TADA1,ZC4H2,PITHD1,LEP,SH3BP4,UBE3A,OR4B1,PDZK1IP1,PDE6D,OR5K1,TNIK,S100B,LRFN3,ZDHHC24,ARF6,B3GALT2,PPT1,FGR,MRPL12,RCHY1,FAM20C,SPHK2,RPL7A,CXXC1,LSM12,FIG4,DOK5,MAP2K3,SEC22A,DCTN4,ARF1,EIF2B2,ZMYM6,MRPS26,PHF7,HMGB1,THAP6,TUBA1B,LRRC14,ZBTB26,EMILIN1,PRDX3,PDCD5,BTBD10,LPCAT3,GPR83,PPIL3,ZCCHC7,PHTF2,CTSA,DPAGT1,HNMT,FA2H,ERRFI1,SERTAD1,KCNIP2,ZHX1,ZNF770,TPD52L1,DUSP18,RPS28,UBXN2B,SMUG1,SVIP,ASCC1,CDH7,SLC37A4,CXCL10,MAEA,FBLN5,FOXD3,LYRM2,KIAA1958,EID2,ZNF345,SDHC,RGS1,ASB11,FAM83A,NOL12,RHOG,COX7B,CDC42SE1,BGLAP,GAD2,RSBN1L,METTL18,TTR,SEC61A1,AASDHPPT,TM4SF20,CCNA2,MAGED2,GJA1,SURF2,SLC29A1,TM4SF18,TNR,OR6X1,BOK,CAPN2,LSM14A,SLC8A1,OR8H3,ABHD8,ICAM2,YWHAZ,STARD3NL,OST4,SLC25A1,HNRNPF,STAMBP,EHD4,CEND1,ZNF511,FAM81A,PCGF6,GRM1,OR4K2,SLCO3A1,SPATA2,ADORA1,KCNJ10,SHPRH,TAF1D,HOMER3,CXCR3,MAGEB10,PSMB7,FBXW7,TNFAIP6,DMTF1,PLG,DLK2,CDK12,TXNDC17,CITED1,ARL4D,LIAS,TNNI3K,CPLX3,GCLC,PSMD10,NPY1R,EPHA4,KCNJ2,GXYLT2,ZNHIT6,PLCB1,GPC1,GPR17,PRSS23,FAM149B1,FRZB,SPP1,TSR2,CHRM3,ARL2BP,ING2,TRIM36,NT5DC1,MRPS18C,PROK1,JAK2,PAQR3,CREBZF,PTP4A3,PLSCR1,DCAF12L2,CBLN1,STK3,COMMD9,HSPB2,LY6H,TNKS2,LILRA2,CORO6,OIP5,TRIM29,RB1,PNMA3,DPH5,ZBED1,CTXN3,HFE,DDAH1,GPR35,NDUFA1,ALG11,FAM53C,MCL1,HCAR1,TMEM127,GSTA2,LXN,TCEAL8,YIPF3,RPS2,B4GALT4,CAV1,ICOS,RGL2,ITGB5,TRIM34,TMEM205,NDUFC2,PRND,CPLX2,ABHD10,HUWE1,CNTROB,FTSJ1,SREK1IP1,AKR1C1,MRPS11,CSNK1G3,RAB39B,CYP3A43,SPEM1,PDE4B,TTPAL,UBE2L3,CCIN,MEPCE,EIF3G,TIMP4,ACCS,XRCC5,ADTRP,SNRPG,CDC20,ZDHHC4,WDR5B,SEC13,IL2,VMAC,TNFAIP8L1,NBN,PEX13,AIPL1,FHOD3,SLC35B3,WDR11,NHEJ1,TYROBP,OLR1,SLC19A3,NDST3,FBXO8,PRL,MPPED2,CDC7,MRPS34,CYP2C9,IGSF11,DUSP21,TRIM45,ATAD1,MGAT4A,RBBP8,SGMS1,FOXA3,KLHL1,CARTPT,SESTD1,BANF1,ABHD12,NF2,PARP2,RPL26L1,PHF13,CGGBP1,SUMO2,TFB1M,LZTFL1,SNRPB2,KLF3,CCR4,GGH,IL17F,PPAT,CYGB,NUDT9,UBE2E2,FSTL1,POLDIP3,RHOBTB3,HGS,CD81,ELK3,CRISP1,DPH3,LRRC40,TMEM170A,RNF133,COX6B2,PRKRA,TSPAN17,GNRH1,WDSUB1,ZNF451,PRKCE,DBR1,TAS2R13,COCH,FEM1C,PIK3AP1,XAF1,COX6C,PICALM,VTA1,RPIA,CRTC2,GSTM4,TMEM38B,TSPAN15,NPM3,NUDT2,ATP1A3,BAX,GH1,PEBP4,PSD2,TMEM185A,NDUFS2,IVNS1ABP,PIK3CA,FAM83B,SNRNP40,JAKMIP2,PSMC3,CDH11,RBM27,ZBTB39,CPT1B,CNN3,ANKMY2,AP1S2,LY96,TMEM47,MAD2L1BP,AKR1B1,TAB1,SF3B1,APEX2,ADORA3,CA2,SNX10,PET117,MTDH,USP6NL,SGTA,TPPP3,ZNF263,SSX2IP,BCL6,SYNPR,TMED9,GSTCD,GTF2F1,DLST,CBX3,DR1,GTPBP8,HS2ST1,TRPC1,ELMO2,LYPD6,ASPA,GABRA1,HSD17B10,PRNP,CAND1,TMEM89,MIS12,SPRY1,RPS10,CLDND1,ETNK2,CCDC106,TKTL1,GIN1,RPL18,TRAF6,TBCCD1,KRIT1,VPS72,KCND3,FUBP3,ROCK2,TRAPPC6A,MDC1,MTCH2,ITM2B,CCSER2,MGMT,TADA3,TRAM1,TMEM196,UBA52,ECHDC1,AP1M1,FUNDC1,IMPA2,YTHDF2,PDE12,ANKRD6,FAM161A,SRFBP1,PFKFB2,ARHGAP12,EIF5B,ACER3,MREG,DIRAS2,CLEC6A,KCTD17,RASSF8,SSBP4,TLCD1,AQP11,RBP2,FKBP1B,LMO2,LCORL,EDA2R,OR13A1,MAGEC2,PSEN1,KIF3C,ATP8A1,CIAO1,GHRL,VPS18,ZNF581,DUSP3,PDE7A,SUCLG2,SCML1,ZFAND6,TYMS,TAPT1,NAA16,GJC1,RUNX1,SLC12A2,ANXA4,RASL12,IL18BP,GALNT2,SNRPE,RRAGB,GRIK1,DLGAP4,CMA1,IGF1,CCR7,SNAP25,RXRG,GORASP2,THUMPD1,PELO,GMPS,TTC9C,BRAP,TANK,SYNGR3,MPG,CDC23,MBD3,ELFN1,DMPK,GALC,RP9,ELFN2,OR5M9,HAUS2,SSPN,GNGT2,CNPY1,LRRC8A,NKAP,LBX1,RDH11,PIH1D1,KCTD3,VEZT,SLU7,MFAP3L,FAM3C,PTP4A2,IRF7,OR8B4,TMEM165,KLHL25,SULT1B1,RPE,ADCK1,CYBRD1,ZNF518B,FAM151B,SLC35E4,SLC25A5,OAZ1,LYZ,WSB1,UPRT,SUPT3H,FXN,MRPS17,SGIP1,MECR,MRPL9,FEM1B,TRIM26,IER3,NUCKS1,CENPL,TOX4,KLRC2,RAMP3,CPNE2,TMBIM1,IFT172,CYTH4,NR1I3,PAIP2B,LRP10,TRIM44,TMEM229B,CMC1,NUFIP2,HINFP,GNB3,CCDC3,VAV2,ITGB8,HSPA5,SERTAD2,GNA11,MPV17L2,CRYBA1,WDR45,THAP8,NRM,PPWD1,GPRASP2,PQBP1,FAM20B,TICAM2,FHL3,SLC22A6,TIA1,SPG21,DDR1,EXOC3,SAP18,TMEM81,CAP2,PIAS1,PNPLA4,NPC2,TMEM115,PARD6A,TCEA2,LRRC28,HSPD1,EIF1AX,OR1M1,CD9,RUSC2,GRPR,IGFBP3,DPEP3,TMEM183A,BTG3,THOC3,PIGA,GLOD4,MX1,BOLL,RBMS2,TGFB2,SLC25A27,VPS54,S100A11,ATG9A,ZNF622,NOG,MED22,ARFGEF1,TLR8,PMPCA,SLC6A2,TNFSF15,AIP,CD40,CRY1,CDK7,SIN3A,PSMD7,SCAND1,PLAC1,CTTNBP2,RAB6A,RGN,PYCR2,TNFSF8,CDIPT,PDE2A,ZNF428,CD34,FBXL4,UNC79,THAP1,CPXM1,EID2B,PRCP,OR4A47,TMEM100,DCTPP1,LDB2,PRSS8,YPEL4,GADD45G,RNASE9,RPA2,TMEM107,PIWIL1,TRAF3IP3,CCDC90B,RGP1,TAB2,SRPK2,IL2RB,PTGFR,IP6K1,P2RY4,FBXW4,CD209,TAS2R7,ST3GAL2,STAR,TRIP4,RPL10,PDCL,SUPT5H,SPINK9,SLC25A24,GK5,GLCE,FAM133B,RNF10,OR51E2,GP9,KRTAP8-1,POLE3,CYP4V2,APLNR,CNPY3,SRI,NCAPG2,PSMD3,DTWD2,GPR160,POLR1D,MDFI,RAP2A,MSH6,TEX261,OR4D5,ZDHHC16,MORC4,CISD1,PIK3R3,LANCL1,MKKS,SLC35B4,TERT,METTL6,RASL10A,GNG13,OR51M1,TUFM,IDH1,IFNA2,KRTAP12-4,MPZ,VPS28,SRC,CD2AP,CHRDL1,TRAF3IP2,PTGER4,DHRS7B,BAHD1,PSMB6,ZCCHC17,PEG10,IZUMO1,IFIT2,SECISBP2L,RAB33B,MCM3,RNF115,CDC42EP3,ENTPD3,MGAT1,RCE1,RGS19,PSMD12,CCT7,CKLF,PAFAH1B1,SLC25A11,KCTD15,MS4A7,PDCD1,HNRNPD,NEUROG2,MTMR6,SEMA6C,LUM,ICAM3,UNC50,HMX2,CHST11,RPL7,YTHDF1,CELF6,NAA50,FCGR2A,MED31,SH3BP5L,KLHL12,PPM1D,IDO1,SERPINI1,SLC39A3,SLC25A28,MSL2,CXCL12,FLCN,RPL35A,RSRC1,ZNF668,CD248,TNFSF13,FLRT3,GRPEL2,STIM1,LRIF1,TMC7,FTL,RIC3,DES,ARHGAP25,ZRANB2,PCDH9,LIN7B,CCL20,MRPS7,ARHGAP5,VTI1B,GLT8D2,FAM162B,SPATA6,MOG,PLSCR4,LRRC57,OSGEP,SCN3B,NMI,RIMS4,NDUFA2,TPGS2,IFNGR1,NUP50,NSFL1C,TMEM190,OGN,SCPEP1,PADI2,POLR2F,POMT2,NDUFB10,TMEM14B,NIF3L1,DHPS,RRN3,UTS2,ARL6IP6,TLE1,BTF3L4,HMG20A,CYP27B1,PNOC,NTPCR,YBEY,MRPL10,IL15,TM9SF4,TCEANC2,LRRC1,NUP37,FERD3L,USP5,MXI1,ITGAV,GPBAR1,RPF1,LDHB,RNF126,TMEM182,FOXP4,AKR7A2,AURKAIP1,FXR2,DRAM1,VKORC1L1,IL1RAP,CNPY4,SMARCA5,FAIM,ELK4,ATP1B1,BAK1,PPP2R3A,GPR85,SLC1A3,SLC22A8,DRD1,SMAD4,FZR1,RILPL2,SMC4,OR8I2,TNNC2,GTF2E1,AK5,RAB22A,FAU,CLVS1,PSME1,CYP2F1,PNO1,KBTBD4,AGAP1,UBE2E3,TRIM10,SLC6A12,PIR,ELAVL2,MOSPD1,OR5AP2,FCHSD2,ISCU,MORN4,GIMAP4,XXYLT1,RPAIN,UNC119B,TBC1D4,PSMC1,MED21,TWSG1,OCIAD2,SSRP1,TTC32,PAIP1,HPGDS,NDUFS3,OR9K2,RLN2,OSBP,DNTT,TLR2,FGF10,DYNC1I1,HECTD1,LGR4,ARMC1,GABRB2,TFEB,CES5A,SYVN1,HSCB,IL6,CCDC122,PPP1R12A,GRID1,RERE,TMEM208,NICN1,RSAD2,RAB30,GABRA2,PFDN4,SST,COMMD5,GSTM2,NAA35,UBFD1,PPIG,NRBF2,PPP4C,EFHD2,DNAJB2,PSMA2,GGT7,GRXCR1,DAD1,ZBTB2,MFN1,TAS1R2,CNR1,PLA2G12A,CAMLG,SLAIN2,NPY,CPNE1,GNB4,CNTN1,ZER1,ACTB,DDAH2,MATN4,LNX2,TYW3,SNX18,RFC2,HSP90AA1,LPAR1,CD1A,HDDC2,PPIH,FNDC9,DCUN1D5,PDRG1,FOLR2,SOCS3,PTPN22,RNF121,PGAM1,AP2S1,UGDH,RPS13,CCSAP,EPO,EID1,ZNF280B,MMP21,NFKBIB,CHCHD3,KCNMB1,TRMT1L,GABARAPL1,CD46,GNAI2,UCK1,CDC123,PEX5L,COMMD2,TM9SF1,SVOP,MAGOHB,FAM118B,MYCT1,ARL10,CBX5,CDC42EP2,PPM1G,DEDD,BOLA3,FLRT2,TMEM209,GFI1,GLYAT,CD1D,PLN,MYD88,MRPL52,FCF1,E2F4,GLRA1,G2E3,RPL3,MTG1,TOPBP1,QPCTL,RBM18,PROM1,TRIM11,C1QL3,MRPS18A,VMO1,CSNK2B,YIPF4,TMUB2,OR4K17,RHOB,MAX,HOXB1,NRSN1,NLRP1,CNPPD1,GZMK,TMEM199,FBP1,STX12,CENPP,RP2,DNAJC27,CD1B,LRRN1,GCC1,KDSR,ZFAND2B,DNAJB6,PSMA5,AOX1,B4GALT1,STARD13,TGIF2LX,CRKL,ATP1A1,NUDT5,NDUFA12,DNAJC25,EGFL8,ILVBL,ARL15,AZI2,KATNAL1,TXNRD1,TMOD1,GTPBP1,KCNMB2,RPS11,NAE1,GSTK1,RAP2C,LAMTOR1,ADNP,EIF4A3,DDX5,CYTH1,CCDC71,SLC1A1,PDE9A,RPS5,CCHCR1,SNAPC2,SLC22A12,CYP17A1,FOXP2,UBE2F,TPSG1,UBN1,MBLAC2,ALG2,PHKA1,COG1,RPL10L,SCYL2,DET1,ZNF330,OR51A4,MCHR2,KLHL7,GTF3C3,RNF14,SAT2,PRRG1,GPNMB,IRF6,RAF1,RGMA,DNAJC10,MEF2C,DRAP1,LRRC4,LITAF,ARFGAP3,ARL4A,SYS1,IL1B,GPR26,PLAA,BAP1,FUT1,RHCE,LY6G6C,TMEM106A,ANGPTL2,PHAX,FKBP10,BAALC,EXOC1,GPX4,RIMKLA,FGF12,SEC62,SNRPD3,ZNF175,LAMTOR3,TP53INP2,TNNT2,GOLPH3L,TESK2,COMT,STK11,SEC61A2,RPS27L,ELAVL4,BVES,RAB14,REP15,TMCC1,GOLGA7,SDC4,CD79B,WASL,DYNLT3,OR4N4,ZBED4,SP4,TMEM31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ZC3H11A,METAP1,TMX2,HTR1A,WSCD1,ELF1,SFRP1,PNMA5,MANBAL,CD86,SLC2A8,ENO2,OXCT1,ZNF704,KBTBD6,EXD2,PTPMT1,FARSA,UBE2H,KLHL3,CFL1,IRGQ,BRIX1,RNF40,RPS26,DDX1,DAP,KDELR2,DPM2,RNASE6,TP53I3,LAMP3,CHPF,MATR3,CNOT6,KCNAB1,CRADD,PPP1R3C,AGTRAP,SEMA5A,MCMBP,APBB3,S1PR4,TNFAIP1,FAM169A,TMEM11,SYNGR2,RNF11,CYTH2,APOC4,TAF7,OR4S2,TLR10,CD28,ZBTB25,FXYD6,NAB2,GNL1,KIAA1143,SELL,ZNF473,ATP1B3,GNB1L,DNAJC2,PPY,CRYAB,ROMO1,ANAPC4,ARPP19,GDPD3,LRRC4B,GREM1,TOMM40,MPHOSPH6,COX4I1,FABP4,MAP1S,BHLHE40,PI16,HDAC3,RPL29,GLRA2,C2CD2L,TXNRD2,DNAJB4,RAP1B,RAD21,AKAP17A,COQ10B,SNX14,AIFM1,FITM1,LAT2,ACTR1A,CARHSP1,KLHL9,NPC1L1,TIMM8A,SDC2,ACVR1B,FAH,RPL10A,CTDSP2,OR5A2,CPLX1,ARMCX3,PLSCR3,CUL3,COX16,FAS,ABCB9,TMPO,MAD2L2,UBTD1,COX6A2,POLR3GL,RBBP4,PAK6,ELOVL4,CHMP2B,SKA1,CSNK1E,GRB10,PIGY,ERVFRD-1,MAN1A2,POLD4,AKT3,CCDC92,RBP5,DNAJC4,EIF3D,SAMHD1,CRYM,PHACTR1,TPH2,KCNS1,SPRYD4,SRXN1,FKBP1A,DNAJC30,P2RY12,ST3GAL4,MRPS18B,EHD3,NT5C2,DOLK,ZMAT2,RPL9,DGCR8,RNF5,TST,LRRTM2,API5,EXTL2,SLC20A1,ALPL,ADIPOR2,LAP3,C2CD2,EFHD1,SAMM50,KCNJ8,ENC1,PYGB,TRIM6,PDE8A,PSMB9,HOMER1,FOXP1,SLC4A10,IZUMO4,AHCYL1,ALDH1A3,NPTX1,CLIC4,COX11,HNRNPH2,HMOX2,BET1L,KLHL26,MMD,WRAP53,GAS2,EEF1A1,TRAPPC4,UCHL3,PAAF1,TFPI,PRKCA,FAR2,SURF6,BRD3,TMEM108,DVL2,TESK1,RPL39,C2CD4C,OR2AT4,TTC33,LRRC8D,VIP,ETFB,NTNG2,FBXO11,RBBP9,SPSB1,WNT10B,DGCR6L,APTX,AP2A1,HRH2,SPINT2,RGMB,ZNF688,BCL2A1,TMEM45B,ZNF22,C1D,ACTR3B,RBM15B,EEF1B2,ZNF189,PABPC1L,TMBIM6,CCT8,DNAJC7,CD83,RPL12,UQCRQ,DUSP22,GFOD2,ADAMTS20,MRPL49,FAM187B,GABRB3,YWHAH,MTMR2,ICAM1,PLCL1,AUH,TFRC,TTC8,IDE,ZNF267,ZNF652,ZNF177,PPME1,HSD17B11,C1QTNF1,HMGA1,SH2D5,OR1S1,UTP6,FOXI3,IPCEF1,MND1,GGPS1,TSPAN11,YIF1A,OR10Q1,CA8,NMBR,LGALS3,MAP4,HHIP,LUC7L3,RAB3A,SMYD3,DDIT4,LCN12,FAM91A1,KPNA2,CTNND1,ORMDL3,FOXJ3,RAD23B,USP30,HAX1,EGR2,LRRC20,RPS3,OR1F1,CHN2,TMEM60,HBEGF,AIF1,CALU,MYL12B,GINS3,ENHO,ZHX3,ATP6V1E2,IL7,ATXN1L,SH3BGRL,EXOSC3,SRSF4,NECAP2,PID1,GPR146,OPTN,KCTD11,APPBP2,CLEC7A,ARPC2,POLR2D,SNX12,KRT222,CNTFR,NEURL2,PDP2,SMNDC1,NDP,SNX33,TMEM42,USP13,MED23,SDCBP,DRG1,FGF3,SRPRB,CEP85,ERLEC1,OR5B3,BRMS1L,FBXO34,HCST,DHRS1,PAPOLA,CHORDC1,ANAPC16,TLR1,CAPG,OGDHL,CCR5,SAR1B,RHAG,IL12A,PPP2R5A,VASH1,GAPT,TLR7,ACADS,PTGES,RNF128,SERPINB6,SYBU,EXOC5,NAA15,EBLN2,RALA,WDR55,FTHL17,F11R,G6PD,ADK,ALOX5AP,ELOVL6,TFPT,ZNHIT1,MECP2,NUP35,PRDX4,SLC25A14,RASL11A,CLSTN3,TBC1D19,RGS6,OLFM2,ENO1,GNPTG,ORAI2,SERPIND1,CHST7,CRYL1,RPL24,GPD2,OMG,CELA3B,LBR,FBXL7,CYP11B2,PHF21A,SLC1A2,THNSL1,COX5A,CAMP,TRMT61A,RHBDL3,RPRD1B,DCAF4L2,TSPO,SNRPN,LYPLA2,STYK1,POP7,RNF181,RPS12,CYB5D2,TXN,MAF1,MTHFS,DUSP6,PPIF,SETD7,DAG1,PML,GABARAPL2,DNASE1L1,PSMA4,OR10A7,ZNF250,SERTAD3,MT3,EIF1B,GABPB1,SCGB1C1,ARF4,TAX1BP3,ZNF790,RDH12,CALY,TNFSF12,TP53,PPM1M,CRELD1,NFKBIL1,INMT,PRDX6,KRTAP3-1,TAX1BP1,AP2M1,KIN,STX7,SENP8,GADD45B,HBA1,LIMS2,GPC4,MZT2B,NECAP1,OSGIN2,TRIM35,TRAFD1,PKIA,PPM1B,GSTM3,SYNDIG1,TSEN34,FTSJ3,SLC25A46,TBC1D17,TMED4,HEXIM2,HSD17B1,PTRHD1,TOX,RWDD4,IRF8,CYB561,BET1,FCER1G,UAP1,THAP7,PTAR1,MGAT5B,CRLF3,INO80E,DEPDC1B,PTEN,RLIM,ADAM21,CXCL13,ABHD5,EPHX1,MOXD1,CCDC160,RPA3,SIT1,FDFT1,NEGR1,SDHB,GFPT1,ATG4C,SNRNP48,FRRS1,RWDD3,TXNDC12,ZFAND2A,MME,METAP2,SEC22C,SMG9,MUL1,MAPRE1,NRN1,GNAZ,RTN4,GAMT,ISX,TOMM6,SIAE,RNF144B,ARG2,DNAJB9,GNG12,PABPC1,NTRK2,TWIST2,APOBEC3G,CNRIP1,FKRP,LPAR2,OR10A4,USP15,ELMOD2,CTSC,TMEM126B,NDUFS6,UBE2K,PDE1B,PIK3R2,PCNA,DDX23,SPRED2,OPRM1,CDAN1,RHOBTB1,CD247,FZD3,IKZF5,CHST2,NXT2,FBXO44,DKC1,ARPC3,LRRC3,HR,DNTTIP1,AGPAT5,PLD3,CREG2,PCYOX1L,THBD,OR4D6,BCL7C,CINP,FBXW11,PPFIA2,CNDP2,TMEM147,USP8,LGALS8,COX8A,DHX38,GPR171,PTK7,PGRMC1,METTL15,BABAM1,NEUROD2,RPL27A,NUDT12,CBLN2,TYW5,SNAP29,JAGN1,NDUFAB1,HTRA2,TMEM170B,TMEM117,MRPL34,NDUFB6,CYP21A2,GNAO1,NCDN,CST11,FASTKD5,SFXN2,SNX22,GNPDA1,COMMD6,KCNJ3,B3GALT1,TMEM30A,AFAP1L2,UBL3,IMP3,IRAK4,TMEM179B,TOMM22,BFAR,REEP3,ST6GAL1,CSGALNACT2,RPL7L1,CSTF3,HENMT1,IL22,STAT2,SAV1,TAGLN3,EPCAM,PCDH17,SRSF7,UBA3,CBLL1,TOR3A,GLRX,SH2D1A,PPP2R5E,SLC11A2,UBB,LMAN1,NPSR1,HSPA13,LSM10,ANKRD34B,LRRTM3,DAAM1,MRPL11,SCLT1,PMP22,SERPINA1,STX11,OR2Y1,LARP4B,TSPAN18,GANAB,RPS6KA4,BBS5,XCL1,OCRL,ZNF664,MAT2B,MLC1,DDX46,PDHB,CCDC134,SLC30A7,SLC6A6,TRIM15,RELL2,RAB27A,GRAP2,RPS7,PSMD4,NPPC,OVOL1,DHX15,RHEB,FBXL14,TPD52,DBT,RAPGEF5,ELOVL7,DAPK3,DSTN,RPS27A,PCDHB13,SLC16A1,OR13C8,TMEM101,HINT2,NUF2,MRPL18,FGFBP1,MFSD5,CHAC2,G3BP1,PSORS1C2,POP5,METTL21A,OXTR,KCNC1,PGGT1B,SLC38A7,CHCHD4,CHIC2,LAPTM4A,FBXL19,MRGPRX3,MTA2,CCDC86,SUFU,ZMYM3,PSMB1,DKK1,HERC4,NR2F6,ASNSD1,CNTN2,RPS16,KRAS,RRM1,RBM22,TOM1L1,KDELR1,BAG3,ZNF365,ILF2,ORC5,OXSR1,SCGB1D1,NLRP3,ILDR1,CCS,RASD1,OLFM3,SCG3,BMPR2,COMMD3,PPP1R1B,RND2,CHPF2,CFC1,OTOS,CNOT2,CRHBP,ZNF326,PLEKHO1,MYBL2,ERAS,GSTM5,FCGR1A,VGLL4,SCML2,GPR176,PKP4,CLDN12,ELF5,CCNY,CHKB,CLEC2B,CBR3,SEPHS2,JKAMP,ADD1,APOBEC3H,LANCL2,PRKACB,ASB7,KLF1,FEN1,CLPB,VDAC1,ODAM,CHMP4C,CEP19,SOX14,PDAP1,CX3CR1,SLCO2B1,FAM219A,IGF1R,UBP1,MAVS,KLHL22,DROSHA,NR2E1,FLOT1,ORC6,THOC2,STARD4,FAM177A1,DCTD,SCNM1,MCM4,CER1,POLR1B,SIAH2,CHCHD6,HOXC4,UPK1A,EPS8,RFXAP,BIRC2,MTM1,NUDT7,IFIH1,UMPS,RAB19,CD1C,SS18,MRPL22,CDCA7L,AQP2,SMAD1,SPC24,CLEC18A,ZNRF1,PPP2CB,FKBP8,GABPA,KLHL24,RCL1,SF3B5,IL2RA,PPAN,VAMP8,MPDU1,PMM2,PRMT6,PRSS12,PPP3R2,TIMP3,TNFRSF1B,CDNF,CEBPG,TGFBR2,USP3,CAPN1,ASZ1,CYP2C8,METTL22,SEMA4C,SLC2A3,FBXO7,RABGGTB,SPIN3,ANP32A,RPL23,CLLU1,STOM,CTTN,VAMP7,HP,PTPN4,GPX7,CHRNB2,RIT1,OR10P1,SOSTDC1,ELOVL1,MORC2,SSR2,SNRPB,TPM3,EFNA3,IFI6,AR,PPM1K,OR8B12,GSTP1,LLPH,NLRP9,TMEM45A,RNASE1,TMEM237,LAMP2,PEA15,RNF8,AKAP8L,EP300,MRPL20,ADAMTS10,STAT5A,COPS5,PRDM4,FEZ1,EIF4A2,MAGEH1,OTX2,LRRC3B,FPGT,APOBEC3F,MAP2K1,PLCB2,HSD17B6,TMEM167B,BST2,PPP2R2C,SPON1,STK4,SLC22A17,TNKS,ST8SIA5,CYP1A1,PLS3,ZNF821,HINT3,SLC25A10,CTXN2,VRTN,GTF2H5,RPRD1A,DDX50,UBLCP1,GSTA1,SERPINB1,TRAK2,ST7,AVPR1B,TEX264,SNRK,ACVR1C,NKIRAS2,RBM38,TMEM41A,IL1R2,KLF9,STUB1,PIP4K2C,SPSB3,TOR1B,KANSL3,FAM83C,UGT1A1,ABCG2,LTA,MRPS9,IFNB1,BTN2A2,UBL5,CSH1,MNS1,POLB,POLA2,UBASH3B,CCNH,SEMG2,KIAA0513,CLDN9,SLC35F2,SYNCRIP,TRMT112,SLC16A10,DIO1,VGLL2,PTH2,MTF1,PRICKLE2,RNF148,MSTN,RPL27,PPP1R1A,DDRGK1,RPL32,DRGX,SHOC2,HARBI1,TMED5,USP16,TCEAL1,PFDN2,AK3,CLCN6,HMGCS1,SLC25A12,TM4SF19,CRAT,NOTCH2,NAPA,SOBP,PTPN11,GNPDA2,TMOD2,REN,CCR1,SMPD2,NCBP2,ASTN1,TBC1D13,SOD1,ATXN10,DTWD1,DECR2,AVL9,IQCK,TP53INP1,VEGFA,FAF1,SLC7A8,RFC3,FBXO22,REG1B,GPM6B,SERPINC1,ACP5,TMEM59L,ATP6V1A,GTDC1,LRRC61,UBIAD1,POLR2B,TSNAX,UBE2W,DHRS13,PARL,TAF10,FAM53B,PRDX1,PREB,NFKBIA,ATG7,TRIM68,ETF1,LRRC8B,DENND2D,COPS7B,KLF4,OR4D2,OR10A6,ACBD6,GTF2H2,MAP3K11,MBL2,TOR2A,PTS,AMIGO1,JPH4,GNG2,EDEM1,VAMP5,METTL14,R3HCC1,CSGALNACT1,SAT1,COL1A2,RMI2,SMU1,SLC35D1,CCNB1,CTDSP1,FAM162A,AKAP14,NDUFAF4,CRYBB2,TFCP2,METTL2A,CLDN1,ABHD6,CRTAP,LCP2,UHMK1,ALKBH5,ERH,ANKRA2,ADIPOQ,FAM98A,ACBD7,RPLP2,TRIM54,HTR1F,OR4Q3,PRPF19,CREBBP,PDCD4,LDOC1,GPAM,RDH10,TGIF2,GREM2,POPDC2,GPX6,CLDN4,SLC13A5,LAMB2,RAB3D,RUVBL1,SDF2L1,GTF2B,CXCL3,NKIRAS1,OAS1,GIT2,ACAT1,TMEM114,ZNF287,TMEM184B,KDM4B,MYO6,CYP2C18,NDUFS8,ZNF740,F9,NKX3-1,OPRK1,GCNT3,TOP1,TMEM144,SRRM5,NRSN2,GPR137,SNX17,BCS1L,APOO,CHGA,GBE1,PAPSS2,TCF23,HTR5A,TMX3,EIF2B3,DNAJC22,TOM1,BCL7B,GPR65,SEC61B,TEX30,HSP90AB1,POLE4,ISG20L2,RER1,FCN2,CDKN2AIP,RGS7BP,SFRP4,ZNF862,ATG4A,SYP,CSRNP1,FUNDC2,MRPS23,TMEM123,DSTYK,ZC3H7A,AIF1L,CCR2,ZBTB5,IPO8,TMSB10,CIDEB,ATAT1,TRIM5,EIF4E,LHFPL4,CALHM3,CDKN2C,COX4I2,SNAPC3,SNCG,BLOC1S2,SSU72,AKAP12,IGBP1,RAB40AL,DDX39A,ZBTB17,BCAP29,FABP7,CD274,EIF3K,CREB3L4,B3GALNT1,SPECC1L,NAT2,RINT1,TSPAN5,OR10G9,BZW2,RPLP0,UBE2V2,IL10,PHYH,FUT9,RTKN,NTN4,ADIG,HOXD12,PELP1,CSNK1A1,ITGA6,COMMD8,TFE3,MT1M,DEFB114,IFNA10,EFNB1,RNF113A,SH3GLB1,PREPL,THTPA,OLFML3,TSPO2,GOLGA7B,SLC19A2,CBR4,VMP1,HSPA8,MSMP,EMP3,CHMP2A,OSTM1,TES,CCDC25,BECN1,LMNB1,GMPPB,CALHM2,ELP3,YAF2,CIB2,TRIM24,ACSL4,MRFAP1L1,TGFB3,DTYMK,ZNF592,MTRF1,EED,ABHD14B,GPX3,PROS1,TMEM204,EWSR1,BRCA1,PCDHB1,ABHD4,KCNK13,RBM7,TRAF2,NPR2,CDK4,NR1I2,CNNM4,DPY30,RGS2,STMN2,NME1,DUSP19,ADPRH,PDHA1,MBD5,KCNMA1,NOS1AP,BCL10,TMED7,RNASEH1,DNAJC3,FKTN,KLK6,SERINC3,SLC41A3,TSN,STOML3,STAU1,PRKAB1,UQCRH,DPEP1,IRF3,CD36,MTHFD2L,ERV3-1,STOX2,PCMTD2,PAX9,STXBP1,KLC2,SOX2,CSNK1A1L,ST3GAL1,DERL1,IL18,ZNF501,CEP97,IFRD2,ST3GAL5,POR,SLC32A1,PARP11,LRP6,TAS2R40,PYROXD2,MRPS21,STK24,LCA5,RAC2,LIX1,KLK5,DDX4,MRGPRX2,LRRC24,GRIA2,FLYWCH2,TOP3B,HIGD2A,B3GNT2,TEX12,TMEM91,ZCCHC9,SLC43A2,GLT8D1,NGB,UQCR11,MOV10,TAF5L,PNPLA8,MYEF2,OR14J1,CDH8,CPSF2,PCGF3,TRIQK,GPX5,TMEM14A,TCEAL7,GDE1,OTUD7B,PPFIA3,SDHAF2,CLIC2,SLITRK2,ELSPBP1,STX18,ORAI3,FOXN2,RBFOX2,GK2,CDKN1A,ROGDI,PGM2L1,GYS1,SLC23A2,AKIP1,PIWIL2,SOS2,HRH3,ZBTB45,ABHD13,INHA,RPAP2,OR5L1,RGS5,RAB1B,FAM168A,ACTL6B,LY6G5C,SLC4A8,SNIP1,CCDC65,LDHAL6B,HMBS,CD2BP2,TDRD7,NDE1,RBMX2,AMY2B,MRTO4,PTHLH,SLC25A4,SMAD3,PPP2R1A,EIF4B,TMEM59,IL6ST,LYNX1,RPL23A,ELMOD1,MLF2,PLEKHJ1,TIMP1,TXNL1,DERL2,CAV2,CSTF2T,IFI35,FBXO25,PSRC1,C1QL1,SLC6A11,RAB37,FOLR1,AP1AR,RAB5C,PNP,PCDH19,WEE2,TIMM10,SELENOK,STK38,CTNNA1,RAB2A,WDR44,GPIHBP1,TRAPPC6B,CCNF,BEND5,SNRPA,CMPK1,B4GALT3,PDYN,ZFP1,CRBN,CD226,VPS33A,SACM1L,RAB9B,AMT,INPP4A,KCNIP3,EZH2,ARCN1,FGFBP2,STAT6,OR10G7,ISG15,ACADSB,SNX24,WIF1,FN3KRP,DYRK1B,PHYHIP,RIOK2,MRPS28,OAT,POMP,OS9,CLDN22,EGLN3,FOS,DYRK2,LHFPL2,ACAP2,MAFG,SCD5,NFKB1,HNRNPK,PRKAG1,OR2A25,FANCG,STX6,PLA2G15,MAPK1IP1L,TAPBP,HNRNPA2B1,RCBTB1,GGCT,ATP6V1C1,YPEL5,PPID,TPPP,RFTN2,RB1CC1,SLC35E1,CAPZA2,NAA60,CCL8,SFT2D2,RAB23,CMAS,OPHN1,SUMO3,CCR3,OGG1,ZNF687,TMEM50B,JUN,IFNG,S100A8,HIRA,CD47,CBLN4,RHOJ,WWP1,FERMT2,EIF3J,TOMM40L,GIMAP2,GNPNAT1,UTP23,CHI3L1,RNASEL,TNRC6C,SPTBN1,RAB33A,CRYGD,FAM107A,RNF167,TNFSF18,PPDPF,DNAJC8,PPP1CB,TRAM2,FCHO2,CHST1,MPV17,EHD1,UPF3B,RABL3,ZNF576,GCA,KLHL15,RFXANK,TRAM1L1,SESN2,PAPOLB,PLAGL1,ACP6,SYNJ2BP,TMEM164,OR4F6,CRYBB3,FOXS1,PTRH2,TAS2R5,ACTR2,NUS1,SRP14,TMEM106C,KRT7,PLEKHA8,WDR3,GJB2,MANSC1,TMCC2,SELENOS,ZNF609,KCNK10,SLCO1A2,KCNH1,KIAA1191,CCL17,OR2H2,DLG4,GTF2F2,CXCR4,HSPA14,NPY5R,POLR3B,PGR,HAND2,LCN9,BRD9,RBM12,RAN,SQSTM1,GLIPR1,TMEM177,FMO2,BICD2,SERPINA5,RNF122,NAPG,KIAA0408,BNIP3L,CLDN8,ADAMTS1,CXCL14,TUSC3,RPL6,GMPPA,CYB561D2,PPP1R16A,MT2A,ATP1A2,DDX42,SLC7A14,DEGS1,CRYBA2,FCAR,NPTN,CCDC42,CYC1,POU1F1,ID1,PTDSS1,SLC35A2,ARMC8,ENTPD4,KIF2A,BACH1,MIA2,INPPL1,PGAP2,CTSD,FABP5,MRGPRX4,NOP58,SPATS2L,AKR1A1,NFE2L1,RBCK1,MRPS25,PPIB,BPGM,SCAMP2,OR52M1,NUP107,SPEF1,CYP4F8,PRKD3,SLC5A6,DEK,NLGN2,DCAF8L2,NDNF,AP1G2,ANP32B,CHST9,CPT2,NFYA,FAM200A,S100A10,STX8,BATF,TOLLIP,TGFB1I1,DUSP1,PWP2,MTAP,RAB3C,CACYBP,CTSK,URM1,CETN3,BMPR1A,FAF2,RHCG,SPINK13,SCG2,ARHGAP21,MPHOSPH10,S100PBP,TMEM33,MRPL47,KLF10,CCND1,RPGRIP1L,OR2W1,TMED3,ACOT13,COX7A1,FBXO9,LCN6,SETD4,OTUD6B,ZNF174,USP38,SLPI,CERK,USP39,VPS4A,ENPEP,NAB1,SYNGR1,LSM6,RTP4,FGF13,PRKX,PROX1,RAB8B,CTNNB1,CYP2D6,INTS12,SOCS2,SFTPD,OAZ2,CLEC12B,ADCY3,SNRPD2,FAM13B,ESR2,DCAF5,CWF19L1,CDK6,TAPBPL,RRAGA,ETV6,SIRT7,FYTTD1,NOL4,IQSEC1,TRAF7,MMACHC,DUOXA2,MTMR12,ABHD16B,TNFAIP3,ZBTB42,GFOD1,SIVA1,SNAPC1,SNTA1,GPR37L1,NDUFAF2,TCP11L1,SOST,ZNF805,SV2B,HPCA,OR2A2,EIF4EBP2,ALDH1L1,MAK16,TSSC4,POLL,NONO,SPRED1,RBM23,TMED1,HEXA,ADAT1,OCEL1,BRI3,OXNAD1,NQO1,IPP,SPATA2L,TBCE,TAC1,OPA3,LMBR1L,NPVF,IGFBP4,AKR1C2,CDKL2,KIF1C,GAS8,CHRNA7,CD3G,PAOX,BRMS1,ACAA2,RAP1A,UCKL1,WWP2,RABAC1,TIGD7,FBXO30,POLR2I,CD2,ST13,RASGRP2,LPXN,IL34,KCND2,CCL21,NDUFA5,TRMT6,PTCRA,CXCR1,NEDD8,FGF17,HBB,SNAI3,CDC37L1,PELI3,KRR1,NLE1,MSX2,WNT7A,STX17,LEPR,NAA11,NDUFB8,ISYNA1,CXCL1,XPOT,FRA10AC1,PDIA3,OR6M1,NUDT16,GXYLT1,KCNA2,B4GALT6,LHFPL1,HADHA,LEAP2,DHX16,TRA2B,SOX21,RAB4A,SERPINH1,RPL37A,HSPE1,CLDN14,ZKSCAN1,SIPA1L1,STAMBPL1,PGBD2,FUT8,WBP2,GTF2A1,UTS2R,NEK7,SPOCK1,LASP1,PHKG1,MOB3C,OSR2,CXXC5,ENDOD1,ANKIB1,CIRBP,EIF2B5,SH3GLB2,GALE,IL23A,PSMD6,SLC39A9,FURIN,DHX9,ZSCAN1,OR51S1,EIF4EBP3,WDR37,GLE1,AQP4,CREBL2,TXNIP,CCL25,GNMT,ATP2C1,FATE1,RC3H2,RANGRF,NUDT19,THOC1,ABCC5,GSK3A,PRCC,NUBP2,LDHA,UBXN10,SLC20A2,PCDHA5,ZMYND11,SLC7A4,ZNF513,APOBEC3C,GPR162,RNF187,XPO5,SURF4,INTS10,TF,CREB3,RNF103,EEF2,THRAP3,SLC25A32,EFHC1,GJA10,EXOC2,XPO1,SPR,GALNT12,ARFIP1,PPARG,SIX5,TRIM21,ACTA2,ARMCX2,RMND5B,SLC25A21,RBBP7,PGS1,NFIL3,HECW1,TRIM37,ZBTB38,PTPN1,SETD5,HNRNPC,SLC35E3,SPTAN1,RNASET2,LRP12,NPY2R,FAM199X,CLDN11,NIPA2,PAEP,RABL2B,TRAPPC1,HEY2,RBM17,PCDHB8,PKNOX1,ADRB1,ZDHHC14,RFX4,FRMD8,PEX3,RCVRN,CCDC127,CD200R1,PPP3CA,KCNJ11,CRYGB,FGFR1,PYGM,OR4K1,SHC1,CCDC47,SCFD1,TTC4,GHITM,TUBG1,RPL15,CACNB4,PRMT2,TACR3,CIB3,BUD31,TMX4,SRP54,CAMK2G,IMPACT,AGER,CD58,FKBP14,IDH2,RAB18,ARMCX5,ZNF593,PRPF4,ANAPC2,FBXO32,AGK,SMCP,ENPP4,CCT5,PSMB5,MCOLN1,SBK2,SORD,SLC39A7,RS1,KIT,LSM3,AFTPH,OR4D9,P4HA2,JOSD1,SUPT7L,GSTO2,KBTBD2,GNG7,ATF4,GRSF1,RARRES2,CSNK2A1,PIWIL4,KPNA1,TMIGD1,DNAJC5,MYH2,SNAP91,ALKBH4,SLC7A9,PACSIN3,HEBP1,PGK1,VRK1,ROPN1B,MMP9,BTF3,DYNC1I2,CYP27A1,CDC73,UBAP1,ZYX,LHX2,SERPINB10,TSEN54,FBXO42,TMEM215,ZNF24,LYG2,MFSD6L,SYN3,ZCCHC10,GPBP1L1,MX2,TMEM213,AAMP,MEST,FZD4,MTPN,WDR77,ATP6V1G1,RAB3B,CDCA3,SMAP2,KTI12,DNAL1,NDST1,DEFB116,TNFAIP8L2,DHRS3,TBC1D10C,MAGOH,GTF2E2,LBH,JAK1,ABCB1,AZGP1,INO80C,HBE1,PSME2,AZIN1,CHDH,GNRH2,MYL12A,CYP39A1,HSD11B1,LRRC69,SWAP70,FAM8A1,EIF4H,ITK,TLR3,JAKMIP1,ADGB,GPAA1,SENP5,IDH3B,GALNT4,CTNNBL1,GRM2,CYP11B1,RMND1,FAM78A,PPP1R2,MIOS,SLC38A9,OSM,IL15RA,MRPL50,MRPL24,ZNF304,SNAPIN,KLK3,SLC30A5,ENY2,RAG1,MEF2A,IMMP2L,SLC35A1,DHRS4,HSBP1,FGFR1OP2,GABARAP,PRPSAP1,ELMO1,GRPEL1,TCP11L2,LTBR,GAL3ST1,OR4D11,CASK,ING1,P2RY1,STRBP,OR8B8,IRF1,NAIF1,TRIM23,NHP2,UBE2D3,CHRM4,CCT2,ARMCX1,UBE2A,ZNF319,SEC14L1,ZNF397,APOBEC3A,XAGE5,ZMYND19,SLAMF9,TAAR1,CCR6,CLU,ATPAF2,KIAA0232,LMO4,GLUL,CNIH4,NCKAP1,NRP1,CDK5R1,UGCG,MEAF6,LYPLA1,LIG3,SLC17A5,SLC25A31,ZNF671,POLR3H,TMUB1,C1QC,TRIM3,ATP6V0B,ZNF207,MRPL23,GDI2,GFM2,E2F6,EXOSC1,ZMPSTE24,GPR89A,EFCAB7,PDIA6,UBR7,SDR42E1,SNRNP27,PRIM2,CD99L2,TRIM32,KLHDC8B,RNF141,DOK4,ARHGAP1,KLK9,PLA2G5,RND3,CNP,NUDT3,B9D1,LYAR,TOM1L2,UST,PFDN5,EXOC8,MRPL13,MDM2,MGP,EHBP1,TMEM156,GSTO1,SOCS5,AK2,GALNT1,CCDC69,PSMA3,FNDC8,FGD2,APEH,AKT1,DLX1,FIBIN,SNX20,WDR38,L1CAM,TLR9,ASMT,CCNI,RAB11A,PPIL4,CDO1,DPP10,PRRC2A,RPS23,CRABP2,IL20RB,DKK3,SF3B4 |
| 1.132e-03 | -6.78 | PCBP4 (poly(rC) binding protein 4) | protein interactions | 57060 | 43 | 22 | 19454 | 5460 |
HEXIM1,VPS4A,SEMA7A,EZH2,GTF2A2,PSMD14,PPID,WBP11,TMEM126A,SAV1,MEPCE,MRPS18C,TUSC2,SSR3,MIEN1,HSPA8,TRIM11,RLIM,MRPL53,ABCB9,ZNF664,SPMIP9 |
| 1.132e-03 | -6.78 | HIPK3 (homeodomain interacting protein kinase 3) | protein interactions | 10114 | 43 | 22 | 19454 | 5460 |
FAS,TOX4,LIMS2,TP53,SUMO1,CREBBP,SIAH2,AR,HNRNPA1,SIAH1,PCGF3,TRA2B,HNRNPL,VIRMA,TGFB1I1,HNRNPA2B1,SRSF1,GLUL,ZYX,SNIP1,CREB1,UBE2I |
| 1.132e-03 | -6.78 | NF1 (neurofibromin 1) | protein interactions | 4763 | 220 | 83 | 19454 | 5460 |
FAM174A,ATG9A,PRDX1,TOR4A,DDRGK1,ATG7,YWHAG,YWHAH,TIAM1,TRAF6,CAMSAP2,YWHAB,DNAJC7,EIF4E2,HRAS,CD274,TYMS,MIF,TOP1,KCTD3,CDC5L,CAV1,KIF1C,RAF1,MAP2K3,FAF2,SIGLECL1,EZH2,CA14,SYNGR3,STARD13,NOSIP,TESK2,EFNB1,HAPSTR1,SEMA4C,KRAS,CD80,CAMK2G,FLOT1,SRSF12,FAM110B,SCN3B,SPRED1,MYC,AKT1,NDUFB6,BFAR,MAP3K21,YWHAZ,CD226,FBXW11,RHOB,CTSK,EPHA2,CD79B,STUB1,CCNF,PTEN,IL2RA,PRKRA,RHOJ,DYRK1A,ESR2,VIRMA,FAM234A,INPP5E,CDC42,TIRAP,HCST,SIPA1L1,SDC2,WRAP53,RPRD1B,RPA2,AGAP1,RTKN,SIRT7,PML,RPA3,CLK1,FAM53C,NSFL1C |
| 1.132e-03 | -6.78 | CDK5 (cyclin dependent kinase 5) | protein interactions | 1020 | 220 | 83 | 19454 | 5460 |
RPA3,RHOU,CCNI,NUBP2,PPP1R2,HSCB,NF2,EIF5B,MEF2A,CCND3,TUSC2,H1-5,SPDYE4,CCND1,PGRMC1,RND2,CDC42,RPE,CDKN1A,CCNA2,STXBP1,CDK7,PPARG,RPA2,MAP2K1,HEXIM1,HECTD1,CNPPD1,CKS2,CCNF,STUB1,RHOJ,PPP1R1B,SRC,CCNB1,SUB1,GORASP2,CHORDC1,CCT2,RHOB,FBXW11,HSP90AA1,UBE2H,H1-1,HTRA2,SCYL2,AKT2,CCT8,SEPTIN7,PCNA,CDK5,IGF1R,CDK20,UBE2A,PSEN1,UNC119B,CKS1B,TP53,CCT5,MAPK10,TULP3,PIK3CA,TMEM94,CDK5R1,RND3,SH3GLB1,PRCC,RB1,RAC2,CDK6,FZR1,TCP1,RHOH,EGLN3,HSP90AB1,CCT7,HMGA1,GAPDH,RHOG,FKBP4,STX1A,CDKN1B,DRG1 |
| 1.136e-03 | -6.78 | G2/M Transition | REACTOME pathways | R-HSA-69275 | 182 | 77 | 10285 | 3229 |
PSMA1,DYNLL1,TP53,PSMC3,OPTN,CCNA2,PSMD4,RPS27A,PSMB4,PSMD6,PSME2,TUBB4B,SEM1,CEP41,MIR484,ACTR1A,PSMB9,HAUS2,YWHAG,PPP2CB,XPO1,PSMA6,HSP90AA1,MYBL2,TUBB,MAPRE1,RBBP4,PSMB2,PSMD1,FKBPL,CDKN1A,SSNA1,PSMC1,CCNB1,PSMD12,TUBA1A,PSMD14,PPP2R1A,UBB,PPP1CB,UBA52,PPP1R12A,PSME1,CDK1,CDK7,SKP1,FBXL7,PSMD10,CSNK1E,PAFAH1B1,EP300,PSMD7,CETN2,MNAT1,CCNH,PSMB10,PSMA5,PSMC5,PSMB11,PSMA4,DCTN3,PSMB3,PSMA2,PSMB6,FBXW11,NDE1,PSMB1,PSMB7,HSP90AB1,PSMD3,TUBG1,PSMC4,DYNC1I2,CEP70,PSMB5,PSMA3,NEK2 |
| 1.137e-03 | -6.78 | LPP (LIM domain containing preferred translocation partner in lipoma) | protein interactions | 4026 | 121 | 50 | 19454 | 5460 |
G3BP1,UFM1,UBE3A,ZYX,SH3GLB1,PPME1,RHOBTB1,ARPC3,PPP2R1A,KIAA0408,FEN1,HNRNPL,SHPRH,PRNP,TES,XPO1,COPS5,YWHAH,CALR,GMPPA,HSPA5,WASF3,PPP2R3A,FBXW7,SQSTM1,SLU7,RPA3,PML,FKBP10,RPRD1B,P3H1,FGFR1,PICALM,LPXN,DYRK1A,ESR2,VIRMA,EGLN2,ACTB,GSK3A,CCNF,SURF2,CTNNA1,STK11,ATRAID,MAPRE1,PNPO,NIF3L1,NTAQ1,CUL3 |
| 1.137e-03 | -6.78 | EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) | protein interactions | 9521 | 121 | 50 | 19454 | 5460 |
RANBP1,RAF1,RPL15,PDHA1,CHAMP1,RPL18,MTA2,HNRNPA2B1,RNASEH2C,HSD17B10,RPL23A,VDAC1,HUWE1,NAT9,AP1M1,MEPCE,WWP2,KARS1,DDRGK1,MAP3K14,XPO1,RPL24,MED4,ATP6V1A,CCAR2,EIF2S1,PLEKHF2,EGLN3,RPL27A,CDK7,CDC42,SDCBP,RPA2,PIH1D1,RPLP0,HEXIM1,RARS1,BAP1,RPA3,RNF113A,FBXW7,UFL1,MARS1,RPL7A,CUL3,MAT2A,RPL26,UBE2H,TAX1BP1,VIRMA |
| 1.144e-03 | -6.77 | post-translational protein targeting to membrane, translocation | biological process | GO:0031204 | 8 | 7 | 18204 | 5365 |
SEC61B,HSPA5,SEC62,SEC61A2,SEC61A1,SEC61G,SEC63 |
| 1.144e-03 | -6.77 | protein maturation by protein folding | biological process | GO:0022417 | 8 | 7 | 18204 | 5365 |
CHCHD4,FKBP1B,ERO1A,AIP,PRDX4,CALR,FKBP1A |
| 1.144e-03 | -6.77 | regulation of lysosome size | biological process | GO:0062196 | 8 | 7 | 18204 | 5365 |
KXD1,BORCS8,SNAPIN,BORCS6,BLOC1S2,BORCS5,BORCS7 |
| 1.144e-03 | -6.77 | symbiont entry into host cell | biological process | GO:0046718 | 113 | 49 | 18204 | 5365 |
CAV2,CTSB,NRP1,CAV1,TNFRSF14,MOG,CD80,MRC1,VPS18,CCR5,WWP1,F11R,SIVA1,CD81,JPT2,PLSCR1,CD4,IDE,CLDN1,DPP4,CD46,NUP153,WWP2,SLC7A1,ICAM1,CD209,RPSA,PHB1,CLDN9,TFRC,SLC20A2,LAMP3,CD86,HYAL2,AVPR1B,CDK1,CLDN6,EPHA2,VAMP8,DAG1,LDLR,HTR2A,ITGB5,ITGAV,ITGA2,GPR15,NECTIN2,RNASEK,CXCR4 |
| 1.144e-03 | -6.77 | negative regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001243 | 113 | 49 | 18204 | 5365 |
MIR21,RRN3,PPIF,SNAI2,HELLS,HTRA2,XBP1,MIR17,ING2,PARL,NDUFS3,MIR195,CDKN2D,SYVN1,PYCR1,TPT1,KDM1A,IVNS1ABP,BCL2L1,FBXO7,EPO,NFE2L2,NONO,CREB3,ATF4,CCAR2,SELENOS,AKT1,MIR132,TXNDC12,PTPN1,ENO1,CXCL12,SRC,TMBIM6,ACKR3,CLU,MIF,PPIA,MMP9,SOD2,HSPB1,GPX1,CTNNB1,TRIM32,TAF9,IL10,MDM2,VDAC2 |
| 1.144e-03 | -6.77 | NIFK (nucleolar protein interacting with the FHA domain of MKI67) | protein interactions | 84365 | 421 | 147 | 19454 | 5460 |
MRTO4,SRSF1,RPL8,EED,RPL7,LYAR,NOP58,RPS10,WWP2,IFI16,DDX50,DDRGK1,XPO1,WDR12,DDX23,ZCCHC9,RPL23,MRPS26,MED4,TOP2B,ARGLU1,MORC2,RPL31,RPS24,COX8A,KRAS,RPL28,E2F4,TRMT1L,RAF1,MAK16,CHMP4C,EZH2,RPL18,MTG1,GTF2F1,ZMAT2,RPL37A,RPL7L1,RPF1,RPL35,SNRNP40,ESR2,RPL10,RPL19,KBTBD6,APEX1,TNPO3,CUL3,GRB10,NOP16,RAB11A,MYC,PRPF31,ZCRB1,FTSJ3,DNAJB6,H1-1,NSA2,TTC1,CCDC86,DDX5,NMRAL1,RADX,NOP53,STAU1,UFL1,COIL,ZDHHC17,BET1,MFAP1,KRR1,SRP14,PRR3,PRNP,CAND1,RPS16,FZR1,ZNF7,NOP9,ZBTB2,SURF6,DKC1,SPATS2L,GRSF1,CSNK2A1,CHCHD1,MPHOSPH10,SNRNP70,BRD3,RPL10A,NOL12,RPS2,TCOF1,NKRF,RPL3,RPL23A,NOC4L,PAK1IP1,RPL17,MEPCE,RPSA,MRPL47,IMP3,SRFBP1,RPL15,EEF1A1,IK,RBM34,RP9,SRP72,TOPORS,ZNF330,EIF2AK2,CCNF,PSPC1,RPS3,FGFBP1,PRKRA,PHAX,CSNK2B,RBMX2,RPL13A,SRPK2,SMURF1,RPL7A,RPF2,PPP1CC,DNAJC8,RC3H2,NLE1,SIRT7,RPA3,PPM1G,RNF113A,FBXW7,RPL4,DGCR8,WDR3,NPM3,AATF,BRIX1,RPA2,ZNF770,RPLP0,RPL26L1,ZNF574 |
| 1.145e-03 | -6.77 | conjunctiva | COSMIC cancer mutations | conjunctiva | 14 | 10 | 16828 | 4835 |
IDH1,IDH2,KIT,GNA11,HRAS,KRAS,CTNNB1,TP53,GNAQ,TERT |
| 1.146e-03 | -6.77 | regulation of smooth muscle cell migration | biological process | GO:0014910 | 91 | 41 | 18204 | 5365 |
MIR218-1,IGFBP3,AIF1,MIR221,MIR503,MIRLET7B,S100A11,MIR21,TRIB1,MIR140,MIR146A,ITGA2,TLR4,MIR182,MIR20A,MIR214,TACR1,SRC,CYP1B1,TERT,MIR424,MIR448,ADAMTS1,MIR135B,MEF2C,MIR34A,MIR143,MIR15A,IGF1,ABHD2,LPAR1,MIR137,NFE2L2,MDM2,CCL5,MIR638,ADIPOQ,MIR223,MIR1298,BMPR1A,NRP1 |
| 1.155e-03 | -6.76 | DLG1 (discs large MAGUK scaffold protein 1) | protein interactions | 1739 | 214 | 81 | 19454 | 5460 |
MRPS34,KCNAB1,CLDN4,CFTR,CDC42,RND2,SLC31A1,CERS2,STX7,RHOU,LIN7C,RAB9A,RAB5A,NUP50,MYO6,LMNB1,RHOB,LAMTOR1,KCNJ2,CRHR1,KCNA3,NTRK3,RAB11A,LIN7B,CSK,RAB2A,DNAJC5,PPP1CC,RHOJ,DUSP10,ESR2,CTNNA1,PSPC1,GRIA1,CCNF,PTEN,FZD4,LRRC1,DISC1,ADAMTS1,CASK,NUPR1,MTMR2,RND3,DLG3,HTR2A,GNG13,SEMA4C,EPHA4,KRAS,HUWE1,GJB1,FLOT1,PAX6,ATP2B4,DLG1,UBE3A,KCNC1,ADRB1,TIAM1,RHOG,KCNJ10,FAM20C,RAB5C,LAMP2,SPATA2,CTNNB1,LAMP3,RHOH,PRNP,ARF6,HNRNPL,CAV1,STX6,DIRAS3,RAB35,HRAS,KCNA2,RAC2,DLGAP4,GJA1 |
| 1.155e-03 | -6.76 | SVIL (supervillin) | protein interactions | 6840 | 214 | 81 | 19454 | 5460 |
TMOD3,DAPK1,ACTB,UBE2V2,SH3BGRL,GNB1,VIRMA,CCNF,GLIPR2,YWHAZ,BICD2,HSP90AA1,MAPRE1,UBE2H,MYC,SFN,H2BC9,BTF3,AR,PPP1CC,USP14,OXCT1,TGFB1I1,HSPA5,BAP1,DDX39B,FOS,MYH2,HSPA8,TNFAIP1,PPARG,RPA2,LMNA,STOM,TMOD1,SPTBN1,H1-5,WDR77,PPP1CB,GABRA1,CFTR,PRNP,SPTAN1,MYL12A,PTP4A3,HSP90AB1,ADD1,DSTN,TES,NME2,H2AC4,DNAJC7,HAX1,YWHAB,BCL2L1,IFI16,RPL6,YWHAG,NDUFV2,HDAC6,YWHAH,GAPDH,CTNNB1,KRAS,TNF,ERLEC1,TRIM37,CAPZA1,DPM2,FLOT1,ZYX,GPSM3,DISC1,CAPZA2,CHMP4C,ACTR2,NUPR1,CD14,TOP3B,RAF1,ACTN4 |
| 1.156e-03 | -6.76 | leukocyte activation involved in inflammatory response | biological process | GO:0002269 | 34 | 19 | 18204 | 5365 |
TRAF3IP2,AIF1,TLR6,KCNJ8,CX3CR1,AGER,IFNGR1,IL13,TLR9,CLU,TNF,TYROBP,JAK2,TLR2,TLR3,MIR181C,CX3CL1,MYD88,IFNG |
| 1.156e-03 | -6.76 | tricarboxylic acid cycle | biological process | GO:0006099 | 34 | 19 | 18204 | 5365 |
NDP,OGDHL,KGD4,SUCLG2,IDH3A,DLAT,SDHC,PDHA1,SDHAF2,IDH2,IREB2,IDH1,IDH3B,DLST,ACO2,MDH1,ACO1,SDHB,PDHB |
| 1.156e-03 | -6.76 | skeletal muscle tissue regeneration | biological process | GO:0043403 | 34 | 19 | 18204 | 5365 |
SELENON,CD9,IFRD1,EZH2,FKRP,MSTN,CD81,GPX1,IGF1,GJA1,WNT7A,PPP3CA,DAG1,MTPN,LARGE1,WNT10B,BCL9,TMEM182,KPNA1 |
| 1.156e-03 | -6.76 | exploration behavior | biological process | GO:0035640 | 34 | 19 | 18204 | 5365 |
SLC4A10,DLG4,TUBA1A,CRHR1,ATP1A2,NOG,CRBN,PRKCE,EIF4A3,DPP4,UBE3A,NDP,TNR,HTR1A,NLGN2,LRRTM1,COMT,BRINP1,MYG1 |
| 1.156e-03 | -6.76 | negative regulation of amide metabolic process | biological process | GO:0034249 | 34 | 19 | 18204 | 5365 |
MIR29A,MIR361,MIR153-1,CHRNA7,ROCK1,PRNP,NTRK2,MIR24-1,MIR455,MIR298,MIR339,IGF1,MIR186,ORMDL3,CLU,ORMDL1,SPON1,MIR29C,RTN4 |
| 1.157e-03 | -6.76 | epithelioid_sarcoma | COSMIC cancer mutations | epithelioid_sarcoma | 10 | 8 | 16828 | 4835 |
TERT,SS18,SMARCB1,EWSR1,KRAS,CTNNB1,HRAS,IDH1 |
| 1.157e-03 | -6.76 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_IV | 10 | 8 | 16828 | 4835 |
IDH2,MSH6,IDH1,TP53,HRAS,KRAS,EZH2,PIK3CA |
| 1.157e-03 | -6.76 | soft_tissue-fibrous_tissue_and_uncertain_origin-epithelioid_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-epithelioid_sarcoma | 10 | 8 | 16828 | 4835 |
EWSR1,SMARCB1,SS18,TERT,IDH1,CTNNB1,KRAS,HRAS |
| 1.161e-03 | -6.76 | LYN (LYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 4067 | 713 | 237 | 19454 | 5460 |
LAMP2,RAB5C,PPFIBP1,CTNNB1,SPHK2,CBL,ANKRD50,RAB35,TNIK,PTK7,FUBP3,SH2D1A,RHOH,HSP90AB1,HTR2A,TOP3B,FASLG,MED9,ADCY3,CRKL,TOP2B,PIK3CG,EFNB1,MYO1B,KRAS,EPHA4,SLC20A2,CCAR1,MYC,CREBBP,BTF3,SLC1A3,LAMTOR1,SLC38A1,DLG4,ZNF189,FAM83B,ZCCHC7,TOM1L1,RPL10,USP6NL,SYK,PAK2,PALS2,KLC2,BMPR1A,DDX39B,EMC1,ABCC5,CYP4V2,DPP4,PGAM1,CSNK2A1,FCGR2A,FCGR2B,SHC1,TSNAX,HCLS1,SLC39A10,ADD1,MCL1,RAC2,SPPL3,FCHO2,SLC38A2,LCP2,LMAN1,SNAP29,CDK4,RAP1A,TP53,ARHGAP12,TFCP2,TFRC,EXOC3,RBM34,NUPR1,RNF8,PIK3AP1,PALM2AKAP2,ATP2B4,ERO1A,ABCE1,SLC16A1,AKAP12,HNRNPK,TOLLIP,SLC6A8,RAB2A,RPL7A,ARHGAP21,SLC6A6,DTL,ATP1A1,NECTIN2,CSNK2B,MACROH2A1,ROCK1,SRC,SPTBN1,PPP1R8,CDC42,RPA2,E2F6,HEXIM1,CSNK1G3,FCAR,MAIP1,SNAPC1,UGP2,PIK3R1,ATG7,DDX23,ABITRAM,CDKN1B,RASSF8,WDR6,FOLR1,MPP1,SPTAN1,PRKCQ,DIRAS3,MARCKSL1,TULP3,VAMP2,AKT2,ARGLU1,PLCB1,TNF,KIT,SEMA4C,AHCYL1,NIBAN2,PKP4,SCG3,PIK3R3,MAP3K21,ARHGAP19,MYO6,FCER1G,WDR20,RHOB,SLC7A11,HSP90AA1,CD79B,ARF1,LRRC1,ACTB,CFAP91,LAMTOR3,ERH,JAK2,NOTCH2,RND2,MFAP1,UPF3B,TMEM185A,IL1B,CYFIP2,STX7,TNFSF12,CD36,RELL1,HDAC6,LAMP3,RAB23,TIAM1,ESYT1,FGR,HRAS,EHBP1,CDCA3,ARF6,CAV1,OSGEPL1,SLC29A1,CTLA4,ZDHHC8,CASK,DLG1,SEPTIN7,IGF1R,SHISA2,SNAP23,THRAP3,TRIM63,CTNND1,ADD2,CSK,STK38L,IL2RB,DEPDC1B,AR,SKAP2,USP14,RACGAP1,HOXC4,EPHA2,VAMP3,CCNF,GAB1,CTNNA1,RPS20,CFAP298,RHOJ,YES1,FERMT2,UBB,SH3BP4,CEP97,VIRMA,ATG16L1,PDE8A,SF3A1,NFYB,PIP5K1A,SPR,UBA52,CNP,FTH1,JUP,CDK1,SLC12A2,HSP90B1,MET,DVL2,RHOU,MME,INPPL1,PRPF4,PRKCB,ITGA2,CERS2,YKT6,NF2,PIK3R2,CDC42EP4 |
| 1.166e-03 | -6.75 | GRIK2 (glutamate ionotropic receptor kainate type subunit 2) | protein interactions | 2898 | 28 | 16 | 19454 | 5460 |
LIN7B,DLG3,JUN,CTNNB1,SDCBP,GRIK1,CASK,GRIA1,MAP3K11,DLG1,GRIA2,DLG4,PICK1,HNRNPL,CTNND1,VIRMA |
| 1.166e-03 | -6.75 | ZNF133 (zinc finger protein 133) | protein interactions | 7692 | 28 | 16 | 19454 | 5460 |
STK3,MRPS7,FTL,MRPS23,MDM2,RPS27A,HNRNPL,TRIM24,MRPS18B,FOS,ILK,MCAT,TIAM1,STK4,SAV1,TPD52 |
| 1.166e-03 | -6.75 | SPAG7 (sperm associated antigen 7) | protein interactions | 9552 | 28 | 16 | 19454 | 5460 |
SLC25A32,H3C1,RAN,NLE1,RPA3,EWSR1,PSMD14,LMNB1,LXN,CBX3,RPA2,LMNA,BRD3,ACACA,NONO,ANAPC13 |
| 1.166e-03 | -6.75 | HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3) | protein interactions | 3293 | 28 | 16 | 19454 | 5460 |
RMND1,UBB,PYGB,TAX1BP1,ACTB,MLH3,PCP2,CTNNA1,HERC3,ABCB9,SMAD2,PPP1CC,TP53,MTCH2,EMC4,ATG9A |
| 1.166e-03 | -6.75 | SPAG1 (sperm associated antigen 1) | protein interactions | 6674 | 28 | 16 | 19454 | 5460 |
PCNA,RAB35,HRAS,S100A6,DDX39B,GNB1,NOPCHAP1,KRAS,DNAAF10,SSR3,PPP1CC,CSK,RAF1,PRKCA,HSP90AA1,RHOB |
| 1.167e-03 | -6.75 | MAP3K3 (mitogen-activated protein kinase kinase kinase 3) | protein interactions | 4215 | 81 | 36 | 19454 | 5460 |
CCT8,SQSTM1,BIRC2,GTF2I,ZBTB16,PDRG1,RPS27A,VWF,SUFU,UBA52,MAP2K3,CCM2,BIRC5,NFKBIA,GAB1,TRAF7,TCP1,MAP3K3,HSP90AB1,VIRMA,CCT7,UBB,TOM1L1,SMURF1,YWHAH,COPS5,YWHAG,XPO1,TRAF6,BRCA1,YWHAZ,IKBKB,YWHAB,PFDN2,HSP90AA1,PDCD10 |
| 1.169e-03 | -6.75 | OSBPL11 (oxysterol binding protein like 11) | protein interactions | 114885 | 98 | 42 | 19454 | 5460 |
CAND1,ARF6,RHOH,SNAP25,STX6,WDR44,PTPN1,RAB35,SEC61B,ANAPC2,RAC2,SMAD4,LAMTOR1,RHOG,RHOB,RAB2A,LAMP2,AKT1,RAB5C,RAB11A,LAMP3,KRAS,RAB3B,STX7,FKBP8,RPA3,ZYX,TMT1A,RAB5A,RAB9A,DERL1,IGF1R,RPA2,STIM1,VAPB,CFAP36,RAB4A,FGFR1,TP53,SOX2,SEC62,ST7 |
| 1.169e-03 | -6.75 | MYLK2 (myosin light chain kinase 2) | protein interactions | 85366 | 98 | 42 | 19454 | 5460 |
TES,GTF2A1,H2AZ1,CDC5L,ESR2,HSP90AB1,UQCRH,POLR2B,TECR,TOP1,CCAR2,SPPL3,NOP58,TRIM54,HNRNPA1,YWHAG,HNRNPC,PSMD3,SMARCA5,SLC25A1,HSPB1,SMDT1,HSP90AA1,YWHAZ,H2AZ2,RPS6KA4,FTSJ3,BAG2,FBXO11,HSPA8,MYO1B,SLC25A5,H2AC25,H2AC6,BRIX1,GSTT1,PSMC1,ADRB2,H3C1,CFTR,ACAA2,CDK1 |
| 1.169e-03 | -6.75 | miRNAs involved in DNA damage response | WikiPathways | WP1545 | 50 | 29 | 5310 | 1910 |
CCND1,MYC,MIR34B,MIR373,MIR23A,MIR450B,MIR34C,CDK6,MIR106B,CREB1,MIR25,MIR421,MIR222,MIR449B,TP53,MIR449A,CCND3,MIR542,MIR16-1,MIR221,MIR503,CDKN1B,MIR23B,MIR210,MIRLET7D,MIR145,CDKN1A,H2AX,MIR100 |
| 1.173e-03 | -6.75 | mitochondrial small ribosomal subunit | cellular component | GO:0005763 | 32 | 18 | 19108 | 5553 |
MRPS18C,MRPS16,MRPS33,MRPS23,MRPS21,MRPS9,CHCHD1,MRPS7,MRPS25,MRPS26,AURKAIP1,MRPS34,MRPS17,MRPS11,MRPS18A,MRPS28,MRPS35,MRPS18B |
| 1.173e-03 | -6.75 | organellar small ribosomal subunit | cellular component | GO:0000314 | 32 | 18 | 19108 | 5553 |
CHCHD1,MRPS9,MRPS33,MRPS21,MRPS23,MRPS16,MRPS18C,MRPS35,MRPS18B,MRPS28,MRPS11,MRPS18A,AURKAIP1,MRPS34,MRPS17,MRPS26,MRPS25,MRPS7 |
| 1.174e-03 | -6.75 | SCO2 (synthesis of cytochrome C oxidase 2) | protein interactions | 9997 | 127 | 52 | 19454 | 5460 |
SUGP1,MYC,CUL3,NONO,NTRK3,ILK,UBE2H,DNAJB6,MRPL53,LMBR1L,CCNF,OPTN,MTM1,ARMC6,PARL,ESR2,MAD2L2,SPR,TSHR,RPA2,METTL14,PTPN22,STOM,MET,HECTD1,RPA3,EXD2,EP300,NUBP2,HSCB,SLC25A51,STX7,DYRK1B,CIDEB,MTMR12,PPIB,NDUFB8,AIFM1,THY1,EGLN3,SLC25A12,TOP3B,TP53,TUBA1A,JUN,DDX39A,PQBP1,SFXN1,NDUFA4,OPA3,IGF1R,SRPRB |
| 1.174e-03 | -6.75 | CSNK1G3 (casein kinase 1 gamma 3) | protein interactions | 1456 | 127 | 52 | 19454 | 5460 |
PTP4A3,CAV1,ARF6,RAC2,RAB35,HRAS,RPL23,MED21,RHOG,YWHAG,LAMP3,HDAC6,MDFI,LAMP2,TSPAN10,RAB5C,LAMTOR2,RIGI,FLOT1,KRAS,CACUL1,EIF1AD,ISG20,NUPR1,TSPAN3,NCSTN,TP53,UBB,NCKAP1,ESR2,YES1,TUBB,LAMTOR1,YWHAZ,RHOB,DNAJC5,MYC,RAB2A,RAB11A,RNF11,SLC31A1,CERS2,MRPL34,ARRDC3,RHOU,IRF3,CSNK1G3,ACACA,CDC42,RND2,FAXC,DUSP22 |
| 1.174e-03 | -6.75 | RABL6 (RAB, member RAS oncogene family like 6) | protein interactions | 55684 | 127 | 52 | 19454 | 5460 |
RPA2,ATG16L1,BET1,CDC42,SMC4,STX7,AATF,PACSIN3,DNAJC3,RPA3,RAB9A,RAB5A,EP300,LAMTOR1,NTRK3,UBE2H,SMARCA5,RAB11A,HNRNPC,CPSF2,RACGAP1,FBXO22,CCNF,TUBA1B,DLST,RAB4A,MTA2,TOP3B,TP53,MAP1LC3B,RIGI,PPP1R12A,SREK1IP1,EMC2,SNRNP70,MED29,USP15,PSMD3,ATG9A,MDFI,MOV10,LAMP2,XPO1,TMA16,PRNP,MYL12A,PEG10,STX6,MDM2,CEP19,CCDC71,NKX3-1 |
| 1.174e-03 | -6.75 | UTP18 (UTP18 small subunit processome component) | protein interactions | 51096 | 127 | 52 | 19454 | 5460 |
RPA2,UBL3,EHHADH,ATG16L1,H1-5,STAU1,PSENEN,TOMM20,SIRT7,RPA3,DERL1,EP300,EXOSC4,HSPA8,CCT2,CDKL2,DNAJB6,RPL7A,MYC,BTF3,RHOJ,SPCS1,TCEAL7,SNRPB2,ESR2,CCNF,FGFBP1,HDAC11,RNF181,RND3,CCT5,SOX2,G3BP1,KRAS,RIGI,GOLGA7,RPL31,RPL3,MPHOSPH10,CHCHD1,MPHOSPH6,WWP2,GRSF1,IFI16,DDRGK1,MAP3K14,CSNK2A1,XPO1,SURF6,CCT7,SRSF1,PWP2 |
| 1.174e-03 | -6.75 | SEC22A (SEC22 homolog A, vesicle trafficking protein) | protein interactions | 26984 | 127 | 52 | 19454 | 5460 |
RNASEK,ATP6AP2,SYNE4,RETREG3,ELOVL4,KCNJ2,TMEM106C,CYB561,GORASP2,MGST2,CSK,SCN3B,OPRM1,RNF5,CLEC12B,NMRAL1,STOML3,GRAMD2B,TMEM174,LMNA,HCST,YIPF5,DDIT4L,ERVFRD-1,ERLIN1,TMEM45B,TMEM237,TLCD4,MINAR1,TMED9,HNRNPL,MIF,HSD17B11,SDHAF2,SPINT2,MCOLN1,STX5,PHB1,STX1A,TP53INP1,FATE1,FAM174A,RAB18,GPR37L1,PCNA,PTGES,CYBRD1,GAD2,ICAM3,CLEC7A,SFTPC,LPAR6 |
| 1.174e-03 | -6.75 | URB1 (URB1 ribosome biogenesis homolog) | protein interactions | 9875 | 127 | 52 | 19454 | 5460 |
SURF6,RCHY1,DDX23,RPL10A,CDC23,PLEKHO1,IFI16,KRAS,TFG,RPL28,FGF3,RPL31,RPS24,RPL3,RBM34,LLPH,RPL18,TOP3B,LGR4,RPL15,AURKAIP1,SNRNP40,TAB1,RPL13A,RPL22,APEX1,ESR2,VIRMA,ZNF330,EIF2AK2,LMBR1L,PRKRA,FGFBP1,MECP2,DNAJB6,NLRP3,GPR17,MYC,ZNF668,STAU1,RPL4,NPM3,COIL,SIRT7,RPA3,APOBEC3C,RPA2,MACROH2A2,RPL26L1,RPLP0,RPS14,FGF13 |
| 1.176e-03 | -6.75 | PAK2 (p21 (RAC1) activated kinase 2) | protein interactions | 5062 | 208 | 79 | 19454 | 5460 |
SCLT1,GIT2,EIF4B,FGFR1,ISOC1,PAK2,RPA2,PLAA,CDC42,SNRNP27,PPP1CB,SUMO1,CAPN1,LPXN,PAFAH1B1,ATP6V1C1,SKP1,HSPA5,PACSIN3,STAU1,EP300,SNX33,NUP50,HSPA8,ARHGEF6,PML,RHOU,RPA3,THOC3,SERPINH1,CDKN2AIP,NAPA,ICAM1,MYO6,YWHAZ,TLR9,RHOB,CKB,MCM3,GMPS,LDHB,SFN,CSK,MYC,NIBAN2,SRC,YES1,RHOJ,STAT1,AP2M1,OPTN,PSMC3,MOB3C,EEF2,TRAF2,SOX2,RRM1,RAF1,KRAS,ERO1A,PSME1,AKT2,YWHAB,UBFD1,NCK1,RHOG,GAPDH,YWHAG,YWHAH,TAX1BP3,MAPK4,PDIA3,G6PD,RHOH,HNRNPL,OCRL,RAC2,FBXO32,SYNCRIP |
| 1.181e-03 | -6.74 | ULK3 (unc-51 like kinase 3) | protein interactions | 25989 | 59 | 28 | 19454 | 5460 |
ISG15,TRAF2,CFTR,SPTBN1,CCT5,TP53,TANK,CBX3,GTF2IRD1,BIRC2,SNRPA,RPA3,CCT8,RBCK1,YWHAG,HSP90AA1,YWHAB,RCL1,CCT2,YWHAZ,WDR82,AIP,H2AZ1,CBX5,DEK,CCT7,HSP90AB1,TCP1 |
| 1.181e-03 | -6.74 | PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D) | protein interactions | 8493 | 59 | 28 | 19454 | 5460 |
SPPL3,PSMD4,TMOD3,NAT2,PSMD6,MDM2,DIRAS3,CDC5L,DKK3,PSMC5,CDK5RAP3,YWHAB,KPNA6,KDM1A,G3BP1,H3C1,KPNA2,PTGES3,RAD21,GLCE,HAPSTR1,ERRFI1,TP53,H2AX,NUP153,ACTN4,CDKN1A,NTPCR |
| 1.181e-03 | -6.74 | STK17B (serine/threonine kinase 17b) | protein interactions | 9262 | 59 | 28 | 19454 | 5460 |
SLC2A1,KCNIP2,TMEM30A,TRIB1,FAM174A,GPR17,PRPF31,EIF3D,BUB3,PSMD6,CHP1,H2AZ1,EIF3K,CHRM4,ADD1,TOX4,UBAC2,COMTD1,UBA52,FAF2,HCST,FAXC,LPAR6,WBP11,CD80,GNL1,NKAPD1,RPS24 |
| 1.181e-03 | -6.74 | ACSF3 (acyl-CoA synthetase family member 3) | protein interactions | 197322 | 59 | 28 | 19454 | 5460 |
AMACR,RPA3,SLC25A10,HSPD1,RASL10B,HSCB,ABHD10,MRPS7,MATN4,PDHA1,ACAA2,QRSL1,RPA2,HAUS2,RAB28,SDHB,SSBP1,FAHD1,TRIM27,HNRNPL,MALSU1,ETFBKMT,FAM174A,PFDN5,MRM2,MOV10,MTPN,TMEM70 |
| 1.181e-03 | -6.74 | GPRASP1 (G protein-coupled receptor associated sorting protein 1) | protein interactions | 9737 | 59 | 28 | 19454 | 5460 |
H1-5,CHRM3,SNAPIN,STMN2,VIPR1,OPRK1,TACR1,ADRB1,IGF1R,ADRB2,TACR3,PFDN1,HSPA5,TFG,CHRM1,GLYAT,CRIP1,OPRM1,GPRASP2,HMOX2,OXTR,HRH2,CHRM4,CHRM5,GRM1,GRM8,APEX1,OPRL1 |
| 1.187e-03 | -6.74 | positive regulation of receptor-mediated endocytosis | biological process | GO:0048260 | 54 | 27 | 18204 | 5365 |
B2M,VEGFA,GH1,AP2M1,TF,H1-1,ATAD1,CD63,PPT1,PCSK9,CCL19,PICK1,HNRNPK,GREM1,SFRP4,AP2A1,WASL,CCL21,SYK,CLU,ANGPT1,CBL,TBC1D5,IL4,APLN,HFE,SGIP1 |
| 1.187e-03 | -6.74 | positive regulation of immunoglobulin production | biological process | GO:0002639 | 54 | 27 | 18204 | 5365 |
XCL1,IL10,IL5,MAD2L2,HMCES,CD86,EXOSC3,IL13,TFRC,PHB1,KMT5B,IL6,CD28,SHLD1,IL21,IL4,CD40,TNFSF13,TLR9,XBP1,SASH3,DNAJB9,MZB1,PHB2,VAMP3,STAT6,IL2 |
| 1.188e-03 | -6.74 | negative regulation of mitotic cell cycle | biological process | GO:0045930 | 234 | 91 | 18204 | 5365 |
AURKAIP1,BRINP2,CDK1,TRIM35,BTN2A2,KLF4,JADE1,CTDSP2,NLE1,BRINP1,MIR133B,MDM2,DTL,ZNF207,CDK2AP2,TP53,IER3,TOM1L1,FZR1,VPS4A,BTG1,CDC20,MIR15A,MDC1,KLHL22,BTG2,CDKN1B,MIR193A,GPNMB,RGCC,BRCA1,CHMP4C,MIR21,CDC73,NBN,RPS27L,MAD2L2,RAD21,MIR638,FBXO7,RBBP8,MIR137,NDC80,MIR195,TPRA1,BABAM1,MIR29A,EZH2,RINT1,FAM107A,BCL6,NUF2,NOP53,TOPBP1,RPL26,TOM1L2,TNF,CRLF3,OVOL1,IL10,CTNNB1,SPC24,FBXO31,RPA2,BUB3,FZD3,ACVR1,NAE1,CTDSP1,CCND1,PSMG2,BRINP3,DLG1,NABP1,NHERF1,PTEN,MIR29C,CCL2,MAD2L1,PML,CDKN1A,CDK5RAP3,DCUN1D3,CACNB4,MIR16-1,PRMT2,ZNF655,CRADD,IK,RB1,BTG3 |
| 1.190e-03 | -6.73 | ARHGEF1 (Rho guanine nucleotide exchange factor 1) | protein interactions | 9138 | 130 | 53 | 19454 | 5460 |
JUNB,APEX1,TXNDC12,TUBB,LMBR1L,RHOB,RPS29,MCM3,CAP2,MYC,HSCB,FBXW7,THBS3,SQSTM1,RPA3,PRKCA,KLC2,RPA2,MND1,RFXANK,WDR5B,WDR44,SURF6,CDC5L,DCUN1D1,OSBP,DNM2,HRAS,EEF1AKMT3,AHSA1,PPP3CA,NME2,PPIB,XPO1,YWHAG,QPCTL,UBXN6,MEPCE,MRPS18C,CAPZA1,CHCHD2,BLOC1S2,GNAQ,TAF10,AP2S1,PSMC3,DMAP1,PIK3CA,PDHA1,WBP11,CSNK1E,PTS,RAP1A |
| 1.190e-03 | -6.73 | ZBTB7A (zinc finger and BTB domain containing 7A) | protein interactions | 51341 | 130 | 53 | 19454 | 5460 |
SMAD4,CRBN,SHC1,DNM2,SIN3A,MAGED2,RB1,HNRNPL,RPL35A,RPL7,PRNP,TMPO,SP4,TP53,DDX39A,SOX2,EEF1A1,SOX9,MTA2,HNRNPA2B1,RUVBL2,DHX9,HUWE1,RBBP7,RUVBL1,RPL28,SMARCA5,CUL3,RPS17,AR,SP1,HSP90AA1,EIF4A3,NFKBIB,NFKBIA,UBE2I,CBX5,ESR2,RPS14,ACTL6A,H2BC11,LMNA,RPL27,RFC4,XRCC5,HSPA8,SF3B1,HADHA,GTF2I,HDAC3,SMC4,MBD3,BCL6 |
| 1.190e-03 | -6.73 | NRBP1 (nuclear receptor binding protein 1) | protein interactions | 29959 | 130 | 53 | 19454 | 5460 |
GADD45A,UBE3A,RPAP3,DNAJB4,BPGM,KRAS,CA10,DUSP19,RIGI,ARFGEF1,KIF2A,PPP2R1A,TBC1D4,SART3,PPP2CB,CCAR2,SNX1,TSC22D3,C1QL3,SNX2,LANCL1,DHX15,PSMD3,ELOC,COPS5,YWHAG,SAT2,TIAM1,YWHAB,ITM2B,ATP5MK,HSPA8,SKP1,RPE,CDKN1A,CD2AP,PPP1CB,SSR1,ACACA,CCNF,CSNK2B,ADRM1,KLK9,VIRMA,BTG3,LRIF1,SFN,CUL2,MLF1,PPP1CC,ST13,PSMD1,RIT1 |
| 1.191e-03 | -6.73 | SUMO1 (small ubiquitin like modifier 1) | protein interactions | 7341 | 276 | 101 | 19454 | 5460 |
TFCP2,RP9,NFE2L2,TOPORS,ZBTB26,PHC1,NUPR1,TP53,ZMYM3,NUP107,HNRNPK,FAF1,SNIP1,ZNF451,RNF167,MUL1,SMAD4,SLC2A1,BRD3,HDAC6,MIF,TOP1,TSC22D3,MDM2,FAM118B,CDC5L,ZBTB2,ETV6,CDK6,DYRK2,SUMO1,TPT1,SNRNP27,MX1,MEF2A,PIAS1,DDX46,PML,ZBTB6,ARPC2,MECP2,SPOP,UBE2H,MAPRE1,ZCCHC12,PRKACB,AR,CCR2,PLAGL1,RPS3,EIF2AK2,CTTN,UBE2I,TRIM24,RWDD3,HGS,FASLG,RANBP1,PPIL3,JUN,TRAF2,SOX2,ISG15,NUP153,DHX16,ZBED1,ZBTB16,SATB1,MAPK1IP1L,SSRP1,PAX6,PABPC1,TOP2B,EWSR1,PCNA,UBE3A,IFI16,XPO1,MITF,EGLN3,ZHX1,PAK2,MSX1,FOS,TRIM5,EP300,FAS,RBM27,BRCA1,PFDN2,CREBBP,MYC,CUL3,HNRNPC,ZCCHC7,PRRC2A,ESR2,NFKBIA,RAN,ZMYM2,GTF2F2 |
| 1.193e-03 | -6.73 | TAOK1 (TAO kinase 1) | protein interactions | 57551 | 51 | 25 | 19454 | 5460 |
RPA2,DYRK2,GEMIN7,RAF1,CSNK1E,CDC42,MAP2K3,FBXW7,DYNC1I1,RIGI,RPA3,STK26,SQSTM1,MCAT,YWHAB,ABITRAM,STK4,YWHAH,YWHAG,PRNP,FBXO22,LDHA,SPPL3,VIRMA,OCIAD2 |
| 1.193e-03 | -6.73 | NDUFB6 (NADH:ubiquinone oxidoreductase subunit B6) | protein interactions | 4712 | 51 | 25 | 19454 | 5460 |
GAPDH,NDUFV2,NDUFB7,CREB3,STK11,SNX17,NDUFA1,FUT1,MRPS28,SDHB,YIPF3,DDX39A,MPV17,TPT1,TIMMDC1,NDUFA12,CRELD1,NDUFS6,NDUFS3,RPA2,NDUFC2,NDUFB5,RPA3,DNAJC30,HSCB |
| 1.193e-03 | -6.73 | NADK2 (NAD kinase 2, mitochondrial) | protein interactions | 133686 | 51 | 25 | 19454 | 5460 |
PEDS1,RPA2,PIH1D1,HTRA2,IRF2BPL,NPTX1,ETFRF1,ACP6,MTPN,ACTB,DYNLL1,TAX1BP1,TMEM177,KCTD9,PNP,CLIC4,MPST,SEPHS1,FERMT2,SPECC1L,FBXO32,FOLR1,FAIM,RPA3,HSPA8 |
| 1.195e-03 | -6.73 | neuron projection arborization | biological process | GO:0140058 | 18 | 12 | 18204 | 5365 |
ROCK1,SSNA1,ZNF365,PTN,CHRNA7,TUBA1A,IGF2BP1,TPBG,NLGN1,NRP1,PAK6,PHACTR1 |
| 1.195e-03 | -6.73 | regulation of cardiac muscle adaptation | biological process | GO:0010612 | 18 | 12 | 18204 | 5365 |
PPARG,MIR208A,LMNA,ATP2B4,MIR34B,MIR17,PPP3CA,MIR214,MIR20A,SMAD3,MIR34C,MIR25 |
| 1.195e-03 | -6.73 | regulation of cardiac muscle hypertrophy in response to stress | biological process | GO:1903242 | 18 | 12 | 18204 | 5365 |
PPARG,LMNA,MIR34B,ATP2B4,MIR208A,MIR20A,MIR214,PPP3CA,MIR17,MIR34C,SMAD3,MIR25 |
| 1.195e-03 | -6.73 | amyloid-beta metabolic process | biological process | GO:0050435 | 18 | 12 | 18204 | 5365 |
BECN1,PSEN2,NCSTN,IDE,BACE1,PSEN1,APH1A,MME,APEH,PSENEN,REN,DYRK1A |
| 1.195e-03 | -6.73 | TMEM258 (transmembrane protein 258) | protein interactions | 746 | 38 | 20 | 19454 | 5460 |
PSME1,HACD3,PSME2,STT3A,CCNF,SLC17A5,HS2ST1,NUP35,FKBP8,ESR2,DAD1,FUT8,TP53,CCDC47,FAM241A,MFSD6,TIA1,CCDC167,RPN1,STX12 |
| 1.195e-03 | -6.73 | FAM117B (family with sequence similarity 117 member B) | protein interactions | 150864 | 38 | 20 | 19454 | 5460 |
TSC22D3,DYNLL1,HNRNPL,VIRMA,DYRK1A,TNKS2,RNF20,TNKS,AGR2,YWHAZ,PNMA2,YWHAB,PSMC3,SFN,DYRK1B,CTNNB1,FNTB,YWHAH,DDX39A,YWHAG |
| 1.195e-03 | -6.73 | Arhgap30 (Rho GTPase activating protein 30) | protein interactions | 226652 | 38 | 20 | 19454 | 5460 |
ACAT1,HACD3,CPSF1,TACO1,GID8,PPP1R10,SRSF4,TECR,HMGB1,XPO1,CDC42,PPIL4,BAG3,AAMDC,GRSF1,COX5A,UBA52,RPN1,VAPB,PDHA1 |
| 1.196e-03 | -6.73 | SGTB (small glutamine rich tetratricopeptide repeat co-chaperone beta) | protein interactions | 54557 | 202 | 77 | 19454 | 5460 |
SLC25A20,FURIN,HSPA13,GPX7,UAP1,PSORS1C2,DNAJC2,CYB5R1,UBL4A,CMPK1,HEXA,PPIL3,FLOT1,PDE12,AKAP12,ETFA,ADIPOQ,CSH1,SOD3,ERP29,PDIA6,MORC2,TMEM123,RB1CC1,DICER1,TNFSF13,USP15,SYT4,PPIC,SPP1,SMCHD1,KIAA1143,AGR2,LAMP3,PPIB,CD200R1,CALR,DEXI,EDEM1,SRSF10,TMPO,PNPLA8,VEGFC,CD99L2,PRNP,RNF144B,SELENOM,SDC4,ACTA2,PDCL,GTF2IRD1,HSP90B1,IL6ST,ETF1,PGRMC1,CDSN,TMUB1,ATP6V1G1,BRIX1,MED13L,LCP1,EVA1A,LHB,PDF,COL1A2,SDF2L1,SLPI,ZNF668,SRGN,GGH,LMO2,TXNDC12,CHMP5,GNAO1,SGTA,TMEM108,CD79B |
| 1.196e-03 | -6.73 | ARMC5 (armadillo repeat containing 5) | protein interactions | 79798 | 202 | 77 | 19454 | 5460 |
TUBG1,CNOT2,KARS1,SNX1,CCAR2,HSP90AB1,SLC25A12,MAGED2,ATP6V1A,RPN1,TFRC,RBM34,DXO,SERPINA1,RAF1,CD2BP2,ACTN4,RPAP2,EEF1A1,FAF2,EEF2,G3BP1,HUWE1,KRAS,TF,CSE1L,RUVBL1,KPNA2,MCM6,GTF3C3,RIGI,VPS16,ENKD1,SLC25A5,HSPD1,PABPC1,RUVBL2,DHX9,RTCB,XPOT,CA2,HSP90AA1,IGF2BP1,TRIM32,LMO2,CUL3,PSMD1,ATP5F1A,SAMHD1,NCAPG2,TUFM,GMPS,MCM4,PSMD4,ATP5F1B,TUBB,RBBP4,FERMT2,APEX1,USP5,ENO1,GANAB,MSN,HSP90B1,KLC2,RARS1,ACACA,EEF1G,RPL4,HSPA5,UNC45A,MARS1,PPM1G,DDX39B,HSPA8,PSMA3,DLAT |
| 1.196e-03 | -6.73 | LATS1 (large tumor suppressor kinase 1) | protein interactions | 9113 | 431 | 150 | 19454 | 5460 |
MOB3C,MTA2,SF3B5,HPCAL1,TRAF2,PTS,RAF1,MAX,PCGF6,CCAR1,DMPK,FAM168A,JAK1,MYO1B,MAP3K11,ZYX,YWHAB,PPP1R11,HSPB1,RASSF8,HAX1,PPM1B,TRA2A,QPCTL,STK4,YWHAG,YWHAH,SAV1,WWP2,CDC26,DDX50,HSP90AB1,STK3,CNTROB,SPTAN1,NOP58,RAB35,CLK4,RTF2,EIF4B,KCTD12,CRYAB,LMO3,TIMM13,MYH1,IDH3B,NOTCH2,MTF1,CMAS,SAP18,FXR2,BIRC2,SF3B1,TXNL1,SLU7,HTRA2,PRSS1,TNFAIP8,YWHAZ,FTSJ3,TAFAZZIN,SNRPB,CPSF2,MLF2,PRPF31,PKP4,SFN,CUL3,CREBBP,MYC,APEX1,PTPRQ,DES,TAB1,LGALS3,TUBB,SPINDOC,MATR3,GTF2F1,SF3B4,CPSF1,VDAC2,PSMC3,SELENOF,ARPC3,CRABP2,EXOSC8,GLRX5,TP53,TNRC6C,ATP5PB,H2AC6,H2BC14,MOB3B,SLC16A1,RING1,MAP1B,PPP1R12A,SLC25A10,USP15,SSX2IP,AKAP8L,PPIL4,AMY2B,RBM17,H2AC14,CAV1,SLAIN2,DBT,MDM2,DCUN1D1,TFIP11,HEXIM1,RPL26L1,WWP1,JUP,LMNA,RPA2,CDK1,SIPA1L1,PSMC4,SPTBN1,LDOC1,NF2,DLAT,MGP,HNRNPH2,MYH2,DVL2,ARMCX1,IGF2BP1,SPOP,CEP70,PPP1CC,RACGAP1,CEP85,SRC,VIRMA,TRAF1,SMURF1,TECR,ADRM1,MAP3K3,PYGM,ALB,SPIN3,PTEN,UBE2I,MOB4,SF3B6 |
| 1.198e-03 | -6.73 | COIL (coilin) | protein interactions | 8161 | 547 | 186 | 19454 | 5460 |
MLLT6,RPL15,LSM4,FARSA,VRK1,FASTKD5,ARF4,MSH6,SMN1,SLC25A10,SFXN1,HSD17B10,SLC2A1,BRD3,GTF2E1,TOP1,CDK9,ZBTB2,MYBL2,CDK1,LSM2,ATG16L1,SF3A1,SNRPN,DENND2D,CDK7,CERS2,HMGB1,BRIX1,HELLS,ARMCX1,RPA3,SIRT7,PRPF4,GPX4,NTAQ1,ATP5F1A,DNAJC8,SLC25A4,TECR,NUDT18,STUB1,EIF2AK2,RPN1,SNRPE,CYB5B,SART3,RAF1,E2F4,ACTN4,FAF2,G3BP1,DHX16,GTF3C3,RAD21,SSRP1,PREPL,AKT2,SLC25A5,MORC2,NDUFA4,RPS24,DDX23,RSBN1L,AHSA1,HNRNPD,ZBED4,NOP58,BUD31,RPL9,PHB1,AGGF1,VAPB,MFAP1,PGRMC1,COIL,G3BP2,NKAPD1,TRIM5,NUP50,CFDP1,NUBP2,CNIH4,PRPF31,RFC5,TOMM40,TNPO3,SNRPB2,ZNF174,SNRPD2,ZMAT2,SURF4,CBX3,TFCP2,RBM34,IK,SRFBP1,ESS2,PSMA5,KDM4B,FGF12,KPNA2,ZBTB25,SLC25A11,SLC16A1,RBM41,RPL3,TUBG1,CHCHD1,RPS2,KPNA1,TAF9,AGPAT1,ZNF24,PPIL4,CAND1,DKC1,SELENOI,CDC5L,STT3A,DSTN,GNPAT,ARL4D,RPA2,SLC35F6,GTF3C4,WDR3,KDM1A,RNF113A,NIF3L1,LSM6,ATP1A1,CCDC174,C9orf72,SLC25A1,RPL7A,H2BC9,CEP70,SRPK2,RPS3,UQCRC2,CDIPT,ZNF330,CSNK2B,SEC61A1,KDELR1,SMNDC1,ZRANB2,MOB3C,RHOBTB1,UBL5,SUPT5H,PTS,DHX38,TUBA1A,PSMA1,DCP2,RPS4X,RPL31,TOP2B,PICK1,CDC23,DRG1,IFI16,ZCCHC10,RPL6,XPO1,DDRGK1,SNRPA1,POLR2L,KLC2,ZNF362,FXR2,PEBP1,SLU7,XRCC5,GCC1,SERPINH1,MYC,SNRPB,SNRNP40,CBX5,APEX1,VDAC2,ATXN1L,GTF2F1 |
| 1.202e-03 | -6.72 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | biological process | GO:0007193 | 75 | 35 | 18204 | 5365 |
GNAZ,NPY1R,GABBR1,P2RY1,GNAI2,HTR1F,ADORA1,OPRK1,GRM2,CHRM5,GRM1,GPR37L1,RXFP2,DRD3,OPRM1,GPR37,RGS1,LPAR1,CHRM1,EDNRA,GRM8,PDE2A,HTR5A,AKAP12,HTR1A,NPY2R,GNAI3,GPR176,CHRM4,ADCY2,CHRM3,P2RY12,HRH3,MCHR1,OPRL1 |
| 1.204e-03 | -6.72 | EIF4G3 (eukaryotic translation initiation factor 4 gamma 3) | protein interactions | 8672 | 133 | 54 | 19454 | 5460 |
HTRA2,UBE2H,EIF3G,NTAQ1,PSMB6,DYRK1A,APEX1,RPL19,ESR2,VIRMA,EIF4A2,NDN,LMBR1L,PSPC1,EIF3K,VAV2,PSMC4,RBFOX2,EIF4E,PPP1R2,STAU1,RPL4,HSPA8,STK26,BAP1,SIRT7,LSM3,HSPB1,YWHAG,YWHAH,EIF3D,HNRNPL,RPS27L,EIF2B5,ARL10,PSMC3,SIGLECL1,CAMK1,DDX42,EXOSC3,SOX2,WDR37,LGR4,COMTD1,YTHDF2,CCAR1,CTNND1,EIF3E,IMMP2L,EIF4EBP2,EFNB1,BAG2,MRFAP1L1,PABPC1 |
| 1.207e-03 | -6.72 | BMAL1 (basic helix-loop-helix ARNT like 1) | protein interactions | 406 | 101 | 43 | 19454 | 5460 |
USP38,PHF21A,PSMC5,CSNK2B,ZNF174,STUB1,CCHCR1,HSP90AA1,PSMD1,HLF,BTF3,CREBBP,OIP5,KDM1A,EP300,CRY1,SYVN1,RHOU,GIT2,GOLGA5,HMG20A,NUF2,CAND1,PSMB1,AZIN1,RPRD1A,PSME2,ZNF207,CSNK2A1,PSMD3,DYRK1B,HMGA1,PSMD12,HUWE1,UBE3A,BHLHE40,CIPC,TFPT,PSMC3,TRAF2,JUN,CSNK1E,MAX |
| 1.207e-03 | -6.72 | FBXL19 (F-box and leucine rich repeat protein 19) | protein interactions | 54620 | 101 | 43 | 19454 | 5460 |
MED4,KDM2A,MED29,MED10,MED21,MED27,GGH,RNF40,PPIB,CUL3,CREBBP,RPL22,WDR44,CDK9,TRIM29,MED17,SPPL3,RPL35A,TRIM27,INPP5K,CTDSPL2,RPRM,CASK,MED31,GSTP1,RPS11,CDK8,MED23,CTBP1,DENND2D,MED30,TOMM22,TOP3B,SKP1,RIGI,FTL,TUSC2,RNF20,HSPE1,MED11,SLC31A1,MED13L,ATP5IF1 |
| 1.207e-03 | -6.72 | CDK5RAP1 (CDK5 regulatory subunit associated protein 1) | protein interactions | 51654 | 101 | 43 | 19454 | 5460 |
HNRNPL,MATR3,FMOD,TUBB,HEXIM2,GATD3,FAHD1,LDLR,FAM219B,OPTN,SSBP1,ARMC8,RHOG,SNRNP70,NTAQ1,BAG3,AUH,MTG2,ZMYND19,FAM174A,CUL3,MRM2,WWP2,IMMP2L,HSCB,KCTD17,CDK5,HINT2,GPSM3,COX8A,GFM1,RPA3,MAEA,EXD2,XRCC5,AMACR,CDK5R1,MTRES1,RPA2,PDHA1,NDUFS6,EXOSC3,MRPL11 |
| 1.207e-03 | -6.72 | ARL6IP4 (ADP ribosylation factor like GTPase 6 interacting protein 4) | protein interactions | 51329 | 101 | 43 | 19454 | 5460 |
CCNF,GAB1,FOLR1,SRPK2,ESR2,ZBTB2,TOP1,ARMC6,NDN,SPPL3,SNRPB,CSNK2A1,XPO1,PIK3R3,ACO2,MYC,UBE2H,BRD3,COP1,PIP4K2C,SNRNP70,RNF113A,FOS,NKAPD1,SNIP1,SNRPA,DVL2,SSRP1,ARL6,RNF41,AP1M1,TRIM63,DET1,THAP1,CFTR,EIF3J,TP53,ZC3H14,RAF1,ATG16L1,NUPR1,ZRANB2,SKA3 |
| 1.207e-03 | -6.72 | LRP5 (LDL receptor related protein 5) | protein interactions | 4041 | 101 | 43 | 19454 | 5460 |
CSNK1A1,CSNK1A1L,SOST,CDC42,GPIHBP1,ST8SIA4,MTDH,RNF10,LGI1,TIMP3,LRP6,KLK5,SDF2L1,TAFAZZIN,F9,BRINP3,CHST9,PRSS37,VIRMA,RHOJ,ST8SIA5,WNT10B,NCR3,CLEC2B,PI15,TOP3B,B3GALT2,TMEM87A,SMAD9,ST3GAL4,TRAF6,SCGB1D1,DKK1,CTNNB1,CFC1,CCL17,KLK3,DNAJB9,MARCHF4,HNRNPL,NRSN1,RAC2,ETV6 |
| 1.209e-03 | -6.72 | ARID4A (AT-rich interaction domain 4A) | protein interactions | 5926 | 70 | 32 | 19454 | 5460 |
CCNB1,MYC,BRMS1,EID1,SP1,SIN3A,RB1,GATAD1,MACROH2A1,LDLR,ING2,BRMS1L,RBBP4,KLF9,APEX1,CCND1,ZNF704,CDK4,CCNA2,SAP30,ING1,H2AX,SKA2,KLF3,MXD1,CDK1,HBP1,TGIF2,HAPSTR1,TGIF2LX,HDAC3,RBBP7 |
| 1.209e-03 | -6.72 | SLC19A1 (solute carrier family 19 member 1) | protein interactions | 6573 | 70 | 32 | 19454 | 5460 |
CDC42,HCST,RAB4A,RHOU,RAB9A,RAB5A,KRAS,FLOT1,STX7,RAB5C,ATG9A,LAMP2,RAB2A,DNAJC5,LAMP3,RHOB,RHOG,LAMTOR1,LMBR1L,RAB35,HRAS,VAMP3,RAC2,GJA1,RHOH,RHOJ,ARF6,HNRNPL,CAV1,STX6,LMAN1,DIRAS3 |
| 1.209e-03 | -6.72 | S100A11 (S100 calcium binding protein A11) | protein interactions | 6282 | 70 | 32 | 19454 | 5460 |
ESR2,MIF,ACTB,IGBP1,CCNF,OPTN,UBE2H,NME2,S100A11,AGR2,NTAQ1,MOV10,VEZT,MYC,RNF11,SAR1B,EMC1,TNF,GPC1,TRIM37,HSPA8,RPA3,SOD1,S100B,BAP1,PEBP1,E2F6,CCR1,EZH2,RPA2,UBE2F,PLP2 |
| 1.209e-03 | -6.72 | BHLHA15 (basic helix-loop-helix family member a15) | protein interactions | 168620 | 70 | 32 | 19454 | 5460 |
RPS17,RPL7A,NOP16,NOL12,LSM14B,ZCCHC9,RBM27,CHTOP,MAGED2,TRAPPC10,HP1BP3,MRPS9,RPS3,RPL19,KBTBD6,RPS16,RNASEH1,LBR,CFTR,RAF1,RPL26L1,RPLP0,RPL3,MRPS18B,FAF1,RBM23,RPS27A,POLDIP2,RNF41,CHCHD2,H1-6,RPS15 |
| 1.209e-03 | -6.72 | HMGB3 (high mobility group box 3) | protein interactions | 3149 | 70 | 32 | 19454 | 5460 |
MOV10,HMGA1,YWHAH,LMNB1,LHX2,UBE2H,BRD3,ZNF330,CAND1,TOP1,CDK9,PAFAH1B1,ACTN4,LMNA,SDCBP,RPRD1B,CBX3,HEXIM1,OTULIN,SOD1,RPA3,BAP1,EXOSC4,HSPA8,EWSR1,H3C1,G3BP1,HMGB1,NUCKS1,PAX6,SSRP1,SKP1 |
| 1.213e-03 | -6.71 | regulation of membrane protein ectodomain proteolysis | biological process | GO:0051043 | 27 | 16 | 18204 | 5365 |
FURIN,IL10,IL1B,IFNG,PACSIN3,TSPAN17,TSPAN15,TNF,TIMP4,TSPAN5,TNFRSF1B,TIMP1,RGMA,SNX33,ROCK1,TIMP3 |
| 1.213e-03 | -6.71 | PRRC2B (proline rich coiled-coil 2B) | protein interactions | 84726 | 242 | 90 | 19454 | 5460 |
EIF4A2,TAX1BP1,PRRC2A,ATXN1L,DCAF4,MYC,HNF1B,PSENEN,FXR2,YTHDF1,STAU1,G3BP2,HSPA8,CTBP1,ZER1,LSM5,EGLN3,NUP35,FUBP3,CNOT2,DPY30,WWP2,HNRNPA1,CPEB1,EIF3D,G3BP1,SRSF4,RERE,PAX6,TFG,PABPC1,LSM14A,ZC3H7A,VPS33A,PNMA2,RPS11,TOP3B,RAF1,E2F4,SOX2,ERLIN2,DAPK1,SRPK2,VIRMA,PSPC1,CCNF,METAP2,FBLN5,SMAP2,RPS20,EIF3G,RC3H2,PAIP2,EXOSC1,IGF2BP1,MAPRE1,UBE2H,CEP85,FBXO7,AR,DNAJC5,RPA3,SIRT7,EXOSC4,RNF113A,RPA2,PICALM,ATG16L1,RBFOX2,TXNL4A,RPS16,PRNP,SYNCRIP,MOV10,USP3,TLE1,IRF4,LSM4,CNOT7,CNOT6L,RIGI,EIF3E,GARRE1,KLHL15,CERK,FBP1,JPH4,YTHDF2,EGR2,ESS2 |
| 1.215e-03 | -6.71 | IRAK3 (interleukin 1 receptor associated kinase 3) | protein interactions | 11213 | 33 | 18 | 19454 | 5460 |
NSA2,NTRK3,HSP90AA1,TRAF6,RNF152,NONO,HSPB8,LDB1,TBK1,CD14,IRAK4,TICAM2,KRT8,ATP6V0B,ADH1B,MYD88,FOLR1,H2AZ1 |
| 1.215e-03 | -6.71 | TRIM45 (tripartite motif containing 45) | protein interactions | 80263 | 33 | 18 | 19454 | 5460 |
MGME1,TRIM45,UBE2D3,TAX1BP1,TAB1,ZMYND19,TP53,UBE2E2,CDC42,GABARAPL2,UBE2D1,MED10,UBE2E3,TRAF6,UBE2B,BRCA1,TAB2,TFIP11 |
| 1.215e-03 | -6.71 | EVI2B (ecotropic viral integration site 2B) | protein interactions | 2124 | 33 | 18 | 19454 | 5460 |
UBIAD1,TMEM107,TRAM1L1,SLC38A7,PGRMC1,DRAM1,BTN2A2,FAM3C,AQP3,SLC39A9,CDIPT,TRAF3IP3,FUNDC2,CNIH1,TUSC3,TMEM60,NSG1,DESI1 |
| 1.216e-03 | -6.71 | DNTTIP2 (deoxynucleotidyltransferase terminal interacting protein 2) | protein interactions | 30836 | 136 | 55 | 19454 | 5460 |
H2AJ,TULP3,CBX3,HDAC11,H2BC1,RNF8,NUPR1,DNTT,H2AC25,RPL31,FGF3,PICK1,RPL3,PCNA,RPS24,H3C1,CTNNBL1,RPL28,GOLGA7,IFI16,HNRNPA1,DDX23,SPP1,BRD3,UQCR11,IFIT2,SPPL3,SRSF10,EHHADH,RPA2,LMNA,PPARG,RPA3,PML,SIRT7,DGCR8,PSENEN,RPL4,STAU1,RPF2,MYC,ANAPC15,CEP70,PEA15,DNAJB6,RPS3,ZNF330,RPS9,RPL35,RPL13A,SNRNP40,SPCS1,IFI6,ESR2,APEX1 |
| 1.226e-03 | -6.70 | HMGA1 (high mobility group AT-hook 1) | protein interactions | 3159 | 377 | 133 | 19454 | 5460 |
FOLR1,CCDC71,EED,HP1BP3,HNRNPL,ADCK1,HMG20A,BAZ1B,CDC26,DPY30,ATG7,HNRNPA1,CYP11B2,AGR2,POU5F1,HNRNPD,TOP2B,EWSR1,CDK5,RUVBL2,KRAS,G3BP1,RBBP7,TRIM37,CBX7,MCM6,RFC2,HNRNPDL,ZNF263,RAF1,SUPT5H,E2F4,H1-3,JUN,MSX2,ELF1,EZH2,MTA2,SMARCB1,CMTR1,PARP2,VPS72,GTF2F2,RBBP4,TRIM29,TAX1BP1,CBX5,APEX1,CREBBP,MYC,NFYA,PRMT6,HNRNPAB,CUL3,IRF1,RFC5,SMARCE1,BTF3,MCM4,H1-10,LMNB1,SP1,HSP90AA1,RIT1,HIRA,PEBP1,XRCC5,GPC1,STAU1,ACTL6A,H1-5,SUFU,PPARG,MAP2K1,SYNCRIP,H2AZ1,CD274,POLE3,GRSF1,NFKB1,CSNK2A1,POLB,H2AC4,EMC2,RGS6,ZSCAN5A,H3C1,THRAP3,VRK1,OLA1,H2AC6,MDC1,FBP1,TBK1,MRPL11,TP53,H2AX,ZMYM4,ZMYM3,CBX3,CDK8,CHAMP1,CREB1,METAP2,LIG3,ZNF330,EIF2S2,MACROH2A1,UBE2I,HPF1,UBB,SRPK2,SMARCA5,PYCR2,H2BC9,DNAJC8,RACGAP1,MECP2,CHRAC1,UNC79,NCDN,ORC6,BANF1,YKT6,HMGB1,PIAS1,RBFOX2,ATG16L1,ING5,PPP1R8,CDK1,PRKCA,MACROH2A2 |
| 1.227e-03 | -6.70 | FABP5 (fatty acid binding protein 5) | protein interactions | 2171 | 139 | 56 | 19454 | 5460 |
RNF8,CCR1,EZH2,NUDT19,SPRR1B,SOX2,B3GNT2,SAR1B,HSPE1,ASF1A,HINT1,TAGLN3,HSD17B10,RBM3,ATP5PF,BCL2L1,POU5F1,CSTA,GLO1,PGAM1,PMM2,PRNP,SUMO2,AKR1B1,S100A8,WDR82,KRR1,SRSF1,CD274,FKBP1A,CSNK1A1,CDAN1,PPARG,JUP,CFTR,DDX39B,SOD1,RPA3,BAP1,HIRA,UBE2H,MDH1,FKBP1B,PIWIL4,STK24,YWHAZ,MYC,TAGLN2,MSN,TRIM24,CALML5,CMBL,ENO1,UBN1,ENO2,CCNF |
| 1.227e-03 | -6.70 | PNPT1 (polyribonucleotide nucleotidyltransferase 1) | protein interactions | 87178 | 139 | 56 | 19454 | 5460 |
MALSU1,WIF1,SSBP1,PRR3,FAHD1,GATD3,RHOG,CIART,MRPS26,HSPB1,GRSF1,MTRF1,PFDN5,DPY30,AMT,PDE12,NUP107,KRAS,ATP5F1D,FASTKD5,MRPS17,IMMP2L,HSPD1,SLC25A10,HINT2,COX8A,PDHA1,GFM2,RAF1,MRPL11,NUP153,METTL15,MRPL23,VIRMA,PARL,TACO1,MTG1,PRKRA,OSGEP,RIT1,MTG2,AUH,MRM2,PMPCA,TMEM183A,TUFM,HSCB,GRPEL1,SIRT7,EXD2,EP300,YAF2,GFM1,QRSL1,MTRES1,MRPL12 |
| 1.229e-03 | -6.70 | regulation of muscle system process | biological process | GO:0090257 | 249 | 96 | 18204 | 5365 |
CAV3,MSTN,FKBP1B,UCN,MTPN,CLIC2,CAV1,MIR153-1,MIR21,PPARG,SELENON,TNNI1,PI16,MIR30E,GSTO1,TACR1,JUP,PDE9A,GTF2IRD1,MIR208A,TNFRSF1B,MIR143,TACR3,MIR1-1,MEF2A,ROCK1,FBXO32,KBTBD13,TNNT2,MIR34B,FOXP1,DAPK3,PDE4B,PPARA,PIK3CG,HSP90AA1,IL6ST,TOMM70,ENO1,DAG1,MIR34C,ADRA1A,ADORA1,TMEM38B,KCNJ2,TNNC2,FGF13,CTTN,SRI,SETD3,MIR448,SUMO1,CHRM3,GSK3A,CHGA,EHD3,MIR200C,ATP2B4,DLG1,SLC8A1,SOD1,ATP1A2,TRIM63,ATP1B1,TNNI3K,BECN1,KIT,G6PD,MIR20A,GHRL,PLN,MIR17,MIR214,PRKCA,DMPK,OXTR,ATP1A1,MIR145,ROCK2,CAMK2G,PARP2,SMAD3,IGF1,STC1,ITGA2,SMAD4,HAND2,ASB3,MIR208B,MIR25,RGS2,GSTM2,PPP3CA,RANGRF,ORMDL3,LMNA |
| 1.230e-03 | -6.70 | protein transmembrane import into intracellular organelle | biological process | GO:0044743 | 39 | 21 | 18204 | 5365 |
AIFM1,HSPD1,CHCHD4,PEX5L,PEX13,DNLZ,HSPA8,DNAJC19,TRIM37,TOMM20,TIMM23,ROMO1,PEX26,GRPEL2,GRPEL1,TIMM17A,TOMM40,TOMM40L,TIMM21,TOMM70,TOMM7 |
| 1.232e-03 | -6.70 | response to leukemia inhibitory factor | biological process | GO:1990823 | 105 | 46 | 18204 | 5365 |
CREB1,PADI2,TFRC,PTP4A3,SHMT1,PDCD10,SNX10,ICAM1,MIR370,MAT2A,KLF4,VEGFC,SRSF7,EPS8,EXT1,SMARCA5,SRM,NFYB,PIGA,CACNB4,SYNGR1,B3GNT2,FOSL2,SLC25A5,NUP35,MRAS,PHC1,SOCS3,PAX6,EEF1E1,PML,MIR455,LRAT,CHCHD4,FZD4,MIR324,INA,CACYBP,MIR493,XRCC5,EIF4A2,ILDR1,HELLS,MIR342,RPS16,MYBL2 |
| 1.232e-03 | -6.70 | cellular response to alcohol | biological process | GO:0097306 | 105 | 46 | 18204 | 5365 |
CDK4,PTGER4,MIR96,CYP7A1,CYP1B1,BRCA1,MIR342,CTNNA1,JUP,MLC1,CFTR,ACACA,EFNA5,PRKCE,ADCY2,LRP6,GLRA2,SPHK2,PAX6,FOS,ADCY3,AKR1C2,FBP1,KLF4,KLF9,GNG2,AIFM1,AKT1,DAG1,GNB1,UGT1A1,MIR182,P2RY4,SLC23A2,KCNMB1,SOD2,SFRP1,CREB1,IGF1R,CTNNB1,PTGER2,TP53INP1,PTGFR,GLRA1,MIR185,MDM2 |
| 1.233e-03 | -6.70 | Spliceosome, U2-snRNP | KEGG pathways | hsa_M00352 | 20 | 14 | 7161 | 2463 |
SF3B1,SF3B6,SNRPB,SNRPG,SNRPD3,SNRPD2,SNRPD1,SNRPE,SNRPB2,DDX42,SF3A1,SNRPA1,SF3B5,SF3B4 |
| 1.233e-03 | -6.70 | Spliceosome, U2-snRNP | KEGG pathways | M00352 | 20 | 14 | 7161 | 2463 |
SNRPB2,SNRPE,DDX42,SNRPD1,SNRPD2,SF3A1,SNRPA1,SF3B5,SF3B4,SF3B6,SF3B1,SNRPB,SNRPD3,SNRPG |
| 1.235e-03 | -6.70 | SLC6A4 (solute carrier family 6 member 4) | protein interactions | 6532 | 21 | 13 | 19454 | 5460 |
HSPA8,SYVN1,GPM6B,SCAMP2,STUB1,SNCG,RIGI,PTGES3,HSP90AB1,CALR,PPP3CA,STX1A,VAMP2 |
| 1.235e-03 | -6.70 | MOG (myelin oligodendrocyte glycoprotein) | protein interactions | 4340 | 21 | 13 | 19454 | 5460 |
RTN4,TSPAN15,SCAMP2,ATP5F1B,ARL6IP5,SPPL3,PRNP,TRIM37,ADRB2,TSHR,FAM241A,VPS26A,REEP6 |
| 1.236e-03 | -6.70 | RIPK1 (receptor interacting serine/threonine kinase 1) | protein interactions | 8737 | 187 | 72 | 19454 | 5460 |
BAG2,ABCE1,ARGLU1,DDR1,MRPS17,RPS27A,TICAM1,THRAP3,RBCK1,TNF,PELI1,PSMA5,H1-6,TRAF2,RPSA,TBK1,TAB2,RP9,TLR3,GPX7,EEF1AKMT3,PSMB4,UBE2N,H2AZ1,SMAD3,EGLN3,CACYBP,CCAR2,CRADD,MAP3K14,CSNK2A1,XPO1,ATG7,HSPB8,XAF1,COX5A,USP2,UBXN6,NFKB1,USP15,HSPB1,CBL,TRAF6,IKBKB,DCTN3,SQSTM1,MTDH,BIRC2,RCCD1,TNFSF10,RNF11,SERPINB6,HSCB,CLIP3,TRIM27,SNRPD1,SNRPD2,TNFRSF1B,S100A6,CCNF,OPTN,TRAF1,CBX5,TAB1,TAX1BP1,RAPGEF5,MAP3K3,PYCARD,MLF1,TNFAIP3,HSP90AA1,FAS |
| 1.237e-03 | -6.70 | LRRFIP1 (LRR binding FLII interacting protein 1) | protein interactions | 9208 | 142 | 57 | 19454 | 5460 |
USP14,FBXO7,RAB11A,CCNB1,SMARCA5,VMP1,BRCA1,MACROH2A1,PHAX,RTRAF,PRMT5,TUBA1B,DEK,ESR2,PSMD6,ACTB,RBBP4,TMOD3,DAPK1,LUC7L3,PIH1D1,HECTD1,TMOD1,UBE2M,RPLP0,HSPA8,WDR55,SMC4,STAU1,DPY30,IFI16,USP15,MED4,DDX1,TSG101,MYL12A,PRNP,LGR4,TULP3,TNPO2,TUBA1A,ACTR1A,RAF1,MOB3C,NUPR1,MTA2,RTCB,DHX9,RUVBL2,PPP1R12A,MYD88,MSH6,RFC2,THRAP3,TRIM37,RUVBL1,RBBP7 |
| 1.237e-03 | -6.70 | OPRM1 (opioid receptor mu 1) | protein interactions | 4988 | 142 | 57 | 19454 | 5460 |
RTP4,DOK4,ARF1,GNAO1,SIAH1,TNPO3,GNAI2,EXOC5,CYB561,TEX264,CLDN8,EMP3,CLEC12B,EHHADH,ATP6V0E1,SYNGR2,CTXN3,SEC22A,CCDC167,SIGMAR1,LMBRD2,TTI2,RPRM,MAP1LC3A,GRM1,SPPL3,ADCK1,COG1,OPRL1,CNIH1,SLC25A46,PMP22,SLC38A7,MZT2B,SIAH2,SLC41A1,TMBIM6,COPS5,SCGB1D1,DEGS1,CLDN22,SLC39A13,C2CD2L,CLEC7A,RINT1,ZYX,DNAJB4,NSG1,CPLX1,ALOX5AP,LPCAT3,ATP5PB,DOK5,YIPF3,KCNF1,HGS,PLD3 |
| 1.240e-03 | -6.69 | UBCc | smart domains | SM00212 | 40 | 20 | 9717 | 2575 |
UBE2E3,UBE2N,UBE2M,UBE2I,UBE2F,UBE2K,TSG101,UBE2V1,KRAS,UBE2D1,UBE2S,UBE2D3,UBE2G2,UBE2L3,UBE2W,UBE2V2,UBE2H,UBE2A,UBE2E2,UBE2B |
| 1.243e-03 | -6.69 | CTDSP1 (CTD small phosphatase 1) | protein interactions | 58190 | 104 | 44 | 19454 | 5460 |
RAMP3,FAM118B,RAC2,CDCA3,HRAS,PEX3,SLC20A1,RHOG,XPO1,LAMP3,LYPLAL1,LAMP2,KRAS,ZBTB16,CRYBA2,CDKN2C,TAB2,PRKAG1,CTDSP2,TUBA1A,DSTYK,CSTF2T,CENPM,SLC25A4,RHOJ,GTF2F1,PNMA1,SCNM1,YPEL5,ATP1A3,RHOB,LDB1,DNAJC5,BAG3,PTPN11,MORF4L1,LRRC73,TRAPPC6A,SDCBP,STX17,CDC42,IGFBP3,TIMM10,TOMM22 |
| 1.243e-03 | -6.69 | NCDN (neurochondrin) | protein interactions | 23154 | 104 | 44 | 19454 | 5460 |
NCDN,RPA3,CD40,PRCP,PPP1R2,EHHADH,PGRMC1,RFXANK,GOLGA5,RPA2,CIB2,LMBR1L,CCNF,SNRPD2,SEC61A1,SNRNP40,TUBB,ATP5F1B,ATP5F1A,BICD2,ATP1A1,RUVBL2,RUVBL1,SEMA4C,ZBED1,TSSC4,COA1,PTGES3,PAX6,COMTD1,PDHA1,RPN1,GINS4,FBXO32,HNRNPL,FZR1,ILVBL,UBXN6,HMGA1,XPO1,ECD,KIAA1143,ESYT1,DNAJC7 |
| 1.243e-03 | -6.69 | TAF7 (TATA-box binding protein associated factor 7) | protein interactions | 6879 | 104 | 44 | 19454 | 5460 |
EZH2,TAF10,TAF2,TP53,KBTBD4,VDR,MAX,GTF2E2,MAP1LC3B,RUVBL1,RIGI,COPS4,RUVBL2,RHOG,BRD3,TAF9,ZCCHC10,ERCC3,TAF7,CSNK2A1,GTF2E1,CDK9,ATG16L1,CDK7,CCNA2,ZSCAN1,CDC42,STAU1,TRIM22,SPATA25,ATG3,CALU,SETD7,MYC,AR,PRPF31,TAF11,MAD2L1,FAU,PELP1,CPSF1,GTF2F1,TRIM24,GTF2A1 |
| 1.245e-03 | -6.69 | PBK (PDZ binding kinase) | protein interactions | 55872 | 145 | 58 | 19454 | 5460 |
ZBTB26,ZNF526,KIF2A,H2AX,E2F4,TP53,IL1R2,PGAP2,RAF1,TRIM37,HNRNPF,PSMA1,DLG1,MAP4,PSMD10,SMAD4,HP,PSMD3,WDR44,WIF1,ZBTB2,EEF1AKMT3,AKR1A1,EIF4B,ADNP,CDK1,SNRNP27,PPP1CB,RPS14,HSPA5,HMGB1,NSFL1C,TERT,PPIH,ZFP64,HSPA8,RPA3,UBE2H,DNAJB6,OSGEP,MCM3,ST13,GGH,RHOBTB3,MTPN,CCNB1,SUB1,FGFR1OP2,MYC,USP5,JAK2,VIRMA,SRC,ADRM1,PSMD6,PTEN,DOK4,CCNF |
| 1.245e-03 | -6.69 | ERGIC2 (ERGIC and golgi 2) | protein interactions | 51290 | 236 | 88 | 19454 | 5460 |
STX18,LPAR2,EMC2,FKBP8,UBIAD1,CCDC47,VAC14,SLC39A10,TES,STARD3NL,SRPRA,PTPN1,CAMLG,ST6GAL1,FUNDC2,TMPO,LMAN1,TMEM199,CRHBP,FAM20C,OSBPL8,ESYT1,VIPR1,SLC22A6,MTDH,TEX264,ITM2B,TMEM209,YKT6,LPAR1,CDC42,RABL3,SEC22B,FUT8,LEMD3,RPA2,GPR35,SLC12A2,GHITM,STOM,GOLGA5,SYNGR1,IL2RA,SEC63,VIRMA,COPE,GORASP2,HMOX2,CSK,RPF2,VAMP5,EPHA2,RIC3,ARFGAP3,RINT1,SRSF4,EMC8,YIPF3,FAF2,MACO1,STBD1,PARM1,SUPT5H,STIM1,GJA1,STX5,DDRGK1,PDIA3,PPP2R5A,BET1L,TMEM106B,HSCB,EDEM3,TOR1AIP2,PGRMC1,BET1,GOSR2,ARCN1,VAPB,TMEM115,GPR173,S1PR4,RPL7L1,TAX1BP1,SLC30A5,VEZT,TM2D2,SCFD1 |
| 1.246e-03 | -6.69 | skin-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-malignant_melanoma-acral_lentiginous | 30 | 17 | 16828 | 4835 |
IDH1,HRAS,KRAS,SF3B1,GNAQ,JAK2,AKT1,IDH2,KIT,GNA11,RB1,MET,CTNNB1,PTEN,FGFR1,TERT,PIK3CA |
| 1.246e-03 | -6.69 | adenosis | COSMIC cancer mutations | adenosis | 30 | 17 | 16828 | 4835 |
GNA11,MET,KIT,CTNNB1,TP53,AKT1,IDH2,FBXW7,FGFR1,PIK3CA,PTEN,NTRK3,HRAS,KRAS,PIK3R1,IDH1,GNAQ |
| 1.246e-03 | -6.69 | breast-other-adenosis | COSMIC cancer mutations | breast-other-adenosis | 30 | 17 | 16828 | 4835 |
NTRK3,PTEN,PIK3CA,FGFR1,FBXW7,IDH2,AKT1,TP53,MET,GNA11,KIT,CTNNB1,GNAQ,PIK3R1,IDH1,HRAS,KRAS |
| 1.248e-03 | -6.69 | small GTPase-mediated signal transduction | biological process | GO:0007264 | 258 | 99 | 18204 | 5365 |
NKIRAS1,RAP2C,ROPN1B,RAB30,RAB9A,ARHGAP1,RAB18,RAC2,GDI2,EPS8,KRIT1,CFL1,GRAP2,SOS2,BRAP,RAB4A,RRAS2,DOK5,TP53,DOK6,SDCBP,ARHGAP5,G3BP1,RGS19,TIAM1,G3BP2,CDC42,RTKN,ROCK1,SYNJ2BP,RHOJ,RND3,HACD3,RHOG,RAP2A,RAPGEF5,RABIF,CCNA2,RASGRP3,GARRE1,RFXANK,SHOC2,RAB39B,LIPA,RACGAP1,USP8,VAV2,DOK4,RERG,ADGRG1,CDC42EP4,RHOU,BCL6,RALB,ELMO1,SIAH2,RAP2B,GNB1,HRAS,RHOB,ERAS,RGL2,CDH13,RASL10A,CHP1,TAX1BP3,ROCK2,IGF1,KRAS,RAB33A,RAB33B,RHOBTB1,RALA,RIT1,COL1A2,RAP1A,RHEB,CD2AP,CDC42EP2,RAB9B,RGL1,RND2,RHOH,CDC42EP3,CRKL,RAB35,RASGEF1C,AIF1,MAPKAPK5,CDKN1A,RIT2,NCKAP1,RASGRP2,GRAP,MRAS,RB1,RAP1B,DIRAS3,NKIRAS2 |
| 1.248e-03 | -6.69 | molecular condensate scaffold activity | molecular function | GO:0140693 | 41 | 22 | 18094 | 5411 |
NLRP1,NLRP3,HNRNPA2B1,NCK1,NLRP6,G3BP1,PRNP,SQSTM1,MAVS,AR,G3BP2,NFE2L2,BRD3,MECP2,DDX4,ALKBH5,CGAS,NUP153,LGALS3,EZH1,SURF6,RXRG |
| 1.249e-03 | -6.69 | - | gene3d domains | 2.40.50.40 | 69 | 32 | 14470 | 4137 |
CXCL3,CCL11,CCL24,CCL1,CCL23,CCL17,CCL21,CCL3,CBX5,SUV39H1,CBX3,CXCL11,CCL28,XCL1,CXCL1,CBX7,CCL5,CCL18,CXCL14,CXCL8,CXCL9,CCL27,CXCL13,CXCL12,CCL4L1,CXCL10,CCL2,CX3CL1,CCL25,CCL19,CCL20,CCL8 |
| 1.251e-03 | -6.68 | response to electrical stimulus | biological process | GO:0051602 | 44 | 23 | 18204 | 5365 |
NEUROD2,TRIM63,GRM1,RAB3A,GHRL,GRIA1,BTG2,NQO1,SRC,CD14,FZD3,TACR1,KCNJ3,HPCA,HNRNPD,MSTN,SOD2,DISC1,EPO,PTEN,ADSS2,CALR,AKAP12 |
| 1.251e-03 | -6.68 | import into the mitochondrion | biological process | GO:0170036 | 44 | 23 | 18204 | 5365 |
MAIP1,MRPL18,SFXN1,SLC25A28,GRPEL2,TOMM20,TIMM23,ROMO1,DNAJC19,SLC25A39,TOMM40,TOMM40L,DNLZ,SLC25A32,SMDT1,TIMM17A,GRPEL1,SLC25A23,TOMM7,SFXN2,TST,TIMM21,TOMM70 |
| 1.253e-03 | -6.68 | MDN1 (midasin AAA ATPase 1) | protein interactions | 23195 | 178 | 69 | 19454 | 5460 |
RPA3,BAP1,PML,SIRT7,NLE1,EXD2,AKAP1,HSCB,NPTN,STAU1,BRIX1,WDR83,RND2,HCST,CDC42,CFTR,RPA2,GRM2,CCNF,PELP1,SCN2B,DPEP1,GSK3A,PTEN,FBXO22,TUBB,RHOJ,APLNR,ESR2,VIRMA,MYC,CUL3,GPR17,AR,FAS,BRCA1,RHOB,RIT1,UBE2H,ABCE1,IGF1R,SEM1,KRAS,TOP3B,SOX2,H2AX,HDAC11,RNF8,MOB3C,SSR2,PHB1,EEF1AKMT3,CETN3,SUMO2,PRNP,RHOH,ILVBL,CDC5L,UBXN6,LAMP3,YWHAG,DDRGK1,WDR12,H2AC4,AGR2,BECN1,RB1CC1,PEX3,DNAJC7 |
| 1.253e-03 | -6.68 | TRIM32 (tripartite motif containing 32) | protein interactions | 22954 | 178 | 69 | 19454 | 5460 |
TSPAN3,OTULIN,EXOC3,NGB,TMEM59,MAP1LC3B,GABARAPL1,TRAF2,UBE2V1,TP53,RIGI,SRPRB,BAG2,MAP1B,DNAJC7,BCL2L1,YWHAB,UBE2D1,GPRASP2,YWHAH,YWHAG,ATG7,KLHL22,EXOC1,UBXN6,UBE2E2,MDM2,TOP1,MAP1LC3A,PDE9A,UBE2N,SDCBP,GABARAPL2,CFTR,GABARAP,RNF41,UBE2D3,CRYL1,TRIM5,RABAC1,BIRC2,P4HA2,DERL1,SQSTM1,SEPTIN6,RAB29,HSP90AA1,UBE2E3,YWHAZ,TRIM23,FBXW11,NTAQ1,TTC23,AR,TRIM32,MYC,CUL3,SFN,PTPN11,UBE2V2,BTG3,KCTD9,TRIM27,CRYBB3,CCNF,LMBR1L,CIB2,RNF208,LURAP1 |
| 1.253e-03 | -6.68 | CLTCL1 (clathrin heavy chain like 1) | protein interactions | 8218 | 178 | 69 | 19454 | 5460 |
WDR5B,GABRA1,CFTR,KCTD12,RPA2,APOBEC3C,METTL14,CZIB,PICALM,STAMBP,CCL21,HEXIM1,RPA3,IDH3A,EP300,NPTN,B2M,NOP53,CDC123,MYC,CUL3,LIN7B,ANAPC15,CUTA,RIOK2,CDC73,ATP1A1,DNAJB6,SNX5,ENO1,APEX1,VIRMA,TOP3B,OR13A1,PPP2R1A,LGR4,TFCP2,DMAP1,ZNRF1,CAPZA2,EXOSC3,CHMP4C,CCDC69,GNAI3,PPP1R12A,RUVBL2,GALC,NEDD8,TOM1,MEPCE,TMEM199,RAB32,MOV10,RPL6,COPS5,SNAP91,P2RY10,EDC3,AGR2,VCPIP1,STAMBPL1,AHSA1,EEF2KMT,ALYREF,PRR3,MAP1LC3A,RPS10,CX3CL1,CAND1 |
| 1.256e-03 | -6.68 | PPP3CA (protein phosphatase 3 catalytic subunit alpha) | protein interactions | 5530 | 151 | 60 | 19454 | 5460 |
RPA2,P3H1,CDK1,FKBP1A,KLHL3,GABRA1,PDHB,MYOZ3,ADRB2,SOD1,RPA3,ARFIP1,LMNB1,ARMT1,AKT1,FAM163B,GABRG2,GRB10,SLC6A4,MCM3,KCNIP3,TSN,MAT2B,VIRMA,TNPO3,BTG3,IRF2,CCNF,BAD,STUB1,DLST,PSMA6,TUBA1B,GSK3A,PTEN,EZH2,TP53,CRTC2,LBH,JUN,PPP3R2,TOLLIP,FKBP8,RIGI,GABRB2,ATP2B4,PDIA6,PPP3CA,PLAC8,PFDN5,HNRNPL,OSBP,SNX1,PRNP,ELK1,PPIA,ZNF593,CCT7,PTK7,XPO5 |
| 1.256e-03 | -6.68 | TNIK (TRAF2 and NCK interacting kinase) | protein interactions | 23043 | 151 | 60 | 19454 | 5460 |
SLMAP,CAV1,CDC5L,ARF6,GJA1,TNKS,HRAS,TNIK,ANKRD50,STYK1,IKBKB,CCDC92,NCK1,TRAF6,XPO1,INSYN1,KXD1,UBE2A,RIGI,KRAS,TOLLIP,MAPK1IP1L,ERO1A,BAG2,MRPS11,LTBR,CTTNBP2,SIKE1,TAB2,GTPBP1,DNAJC2,DISC1,TRAF2,RAF1,TP53,HOMER1,CTTNBP2NL,SMURF1,VIRMA,GSK3A,INTS10,MOB4,CTNNA1,NTRK3,LAMTOR1,SPCS3,RHOB,BICD2,SMARCE1,FGFR1OP2,SFN,CLU,RAP2A,RPA3,RPA2,FGFR1,CCL3,SPTBN1,NDE1,PAFAH1B1 |
| 1.256e-03 | -6.68 | PLEKHG4 (pleckstrin homology and RhoGEF domain containing G4) | protein interactions | 25894 | 151 | 60 | 19454 | 5460 |
CXCR4,TEX264,TMEM263,ZNF319,NPTN,SMCP,SLC31A1,COIL,RBFOX2,SF3A1,CHIC2,FAM161A,CDC42,FAXC,TIMM23,ARF1,LURAP1,ABHD17A,MATR3,TECR,APEX1,AAMDC,MYC,CSK,PRPF31,TTC23,ISCA2,RPS29,ARMC7,CDKN2C,EFNB1,SLC16A1,SEPTIN7,FGD2,TRIM63,RUVBL1,TFG,DDX39A,RPN1,TENT5D,DCUN1D5,MSRB3,METAP1,EEF1AKMT3,MYEF2,RAC2,PSMB1,MALSU1,NAA11,PRPF18,UBXN6,MDFI,ZCCHC10,SETD5,USP2,P2RY10,HSPB8,MRPS26,SMG9,AKAP8L |
| 1.260e-03 | -6.68 | nucleoside binding | molecular function | GO:0001882 | 8 | 7 | 18094 | 5411 |
ACTN4,POLR2B,POLR3B,POLR1B,ADORA1,OARD1,PNP |
| 1.260e-03 | -6.68 | MAP1LC3A (microtubule associated protein 1 light chain 3 alpha) | protein interactions | 84557 | 233 | 87 | 19454 | 5460 |
TUBB4B,H2AX,GABARAPL1,MAP1LC3B,HPCAL1,IRGQ,STBD1,RETREG1,PRDX4,PSMA1,TNF,CHDH,TOLLIP,TRIM21,BCL9,MAP1B,NEK9,RB1CC1,BCL10,SHC1,TRAF6,ATG7,TP53INP1,TBC1D5,STK4,KXD1,MAP1S,MDM2,CAV1,STK3,TCP1,HYPK,BRD9,SPRED2,PHB1,TP53INP2,TBC1D17,RDH12,NLRP6,PICALM,SAMM50,SEC62,FUNDC1,MREG,HSPA5,BNIP3L,CLU,IL1B,PHB2,RPL4,MAVS,DDX5,HADHA,RAB33B,SQSTM1,DVL2,TEX264,TMEM160,RTKN,PML,SP1,TBC1D25,PDCD4,AP2A1,CCT2,TBC1D16,ATG3,LMNB1,ATG101,TBC1D1,MYC,TRIM32,OPRM1,PYCARD,CBX5,ESR2,PSMD4,MATR3,LGALS3,TUBB,RETREG3,AP2M1,ZNF304,PELP1,SLA2,OPTN,TUBA1B |
| 1.260e-03 | -6.68 | glucose metabolic process | biological process | GO:0006006 | 119 | 51 | 18204 | 5365 |
FBP2,PIK3CA,TNF,ADIPOQ,TP53,CRTC2,PGM1,SLC25A1,G6PC3,LEPR,BRS3,KCNJ11,NPY1R,AKT2,PGM2L1,KBTBD2,SDS,ERRFI1,DLAT,PGAM1,SLC37A4,AKT1,ENO1,FBP1,ATF3,PDHB,LEP,PFKFB2,SORD,ATF4,PPARA,ENO2,PC,INPPL1,FABP5,GAPDH,SLC25A11,CRY1,SLC25A10,OAS1,BAD,PDHA1,GHRL,PCK2,TKTL1,SLC25A12,G6PD,GDPGP1,MDH1,LIPA,PGK1 |
| 1.261e-03 | -6.68 | Membrane Trafficking | REACTOME pathways | R-HSA-199991 | 610 | 226 | 10285 | 3229 |
VTA1,VPS4A,SNAP29,TRAPPC10,RAB9B,AKT3,VAMP7,ARPC3,GABARAPL2,GDI2,ARF4,KIF3B,CLVS2,RALGAPA2,SNX5,PACSIN3,RAB8B,RAB5A,LMAN1,RPS27A,RAB33A,GCC1,TRAPPC13,SEC23A,GALNT2,RAB6A,RAB18,PRKAB1,GOLGA5,RAB35,SAR1B,SCFD1,AP2A1,CTTN,DCTN4,ARF1,TRAPPC3,RAB3A,RAB6B,TMEM115,YWHAB,GRIA1,DYNC1I2,TFRC,MYO6,PICALM,EXOC2,SEC13,EXOC1,PAFAH1B3,UBA52,SRC,VPS54,SNAPIN,GJA10,VAMP3,PAFAH1B1,YWHAZ,AP2S1,RACGAP1,SYS1,RAB4A,RAB5C,SYT2,AP2M1,NECAP1,SEC22C,COPS5,TPD52L1,CD4,FCHO2,RGP1,NEDD8,LDLR,TBC1D25,AP1G2,KLC2,TBC1D13,MYH1,RAB31,MAP1LC3B,COPS4,CHMP2A,STX10,DCTN6,GJB2,RINT1,SNX2,CHMP2B,DNM2,NAPG,MIR711,TACR1,SFN,CTSC,GABARAP,TBC1D1,KDELR2,KIF1C,TBC1D4,BET1,HSPA8,GALNT1,BICD2,GJA1,OCRL,TRAPPC4,CBL,COPS2,COG1,AP1M1,STX18,GOSR1,NECAP2,FZD4,YKT6,RAB11A,TMED3,RAB11B,PAFAH1B2,CD59,TSG101,SURF4,KIF2A,RAB13,TF,AKT1,CYTH2,COPS7A,VAMP2,DVL2,ARFGAP1,DYNC1I1,BLOC1S3,PRKAG1,RALA,FOLR1,AP1S2,TRAPPC6A,ARPC2,DENND2D,USE1,RAB39B,RAB32,TRAPPC6B,GJB1,RAB33B,PREB,GOSR2,KDELR1,TBC1D10C,VPS4B,SEC22B,ACTR2,CYTH1,ARCN1,SPTAN1,CHMP5,KIF3C,TBC1D17,ARF6,SNX18,EXOC5,TBC1D24,STX16,NAA30,RAB14,EXOC8,GJC1,TMED7,COPE,VAMP8,STX6,YWHAH,USP6NL,MIA2,CNIH1,TOR1B,CLVS1,CYTH4,FTH1,TMED9,YWHAG,COPZ2,NAA35,TPD52,AKT2,ARFGAP3,DENND6B,TRAPPC1,WASL,FTL,VPS28,RAB30,CFTR,DYNLL1,SLC2A8,OPTN,BET1L,TBC1D16,SEC22A,RHOBTB3,CHMP4C,MYH2,TFG,HGS,DCTN3,COPS7B,SNAP23,RAB1B,ADRB2,CD3G,RAB1A,NAPA,STX17,TRAPPC2L,RAB27A,SERPINA1,RAB9A,STX5,UBB,SNAP91,SPTBN1,SGIP1,MAN1A2,EXOC3 |
| 1.263e-03 | -6.67 | RBM3 (RNA binding motif protein 3) | protein interactions | 5935 | 157 | 62 | 19454 | 5460 |
RAB5A,NGRN,SNRPA,FLYWCH2,HNRNPA0,MRPL12,RALYL,JUP,MRPS28,PRKRA,PRMT5,AP1G2,CCNF,PAPSS2,APEX1,VIRMA,RPL10,MATR3,RPL39,USP14,MYC,PRMT6,CUL2,CUL3,ELAVL2,MCAT,CASC3,NIF3L1,CHTOP,RC3H2,MRPS18B,MRPL52,KLHL24,HNRNPA2B1,MEPCE,RIGI,HNRNPK,EEF1A1,PAIP2B,RAF1,TP53,ILF2,TMEM94,DNAJC2,PRR3,WDR82,DNM2,FABP5,MRPS9,PHB1,NCBP2,DCUN1D1,FZR1,CAND1,COPS5,HNRNPA1,XPO1,DDRGK1,ELOC,MOV10,MAGOH,SNRNP70 |
| 1.263e-03 | -6.67 | KXD1 (KxDL motif containing 1) | protein interactions | 79036 | 169 | 66 | 19454 | 5460 |
TAX1BP1,BORCS7,UBB,NUDT18,IFT172,TRIM24,TRIM27,TRAF7,BICD2,LAMTOR1,BLOC1S5,NIF3L1,CCHCR1,EXOC5,RNF40,FXR2,RAB9A,BORCS5,USE1,RPRD1B,PTP4A2,AGGF1,WTAP,TFIP11,GIT2,CDR2,BORCS8,DYRK2,ING5,PSMC4,ATG16L1,NDE1,BORCS6,LMO3,KCTD10,CEP19,TMCC2,SLMAP,CDR2L,TNIK,RPL9,STX5,TRAK2,MAP1LC3A,TRAF6,VPS26A,EXOC1,TPM3,UTP6,INSYN1,RNF20,STX11,ZBTB25,TCEA2,NEK9,VPS26B,EWSR1,BLOC1S2,ZC4H2,IFT57,EXOC3,PSMC3,RPS7,SNAPIN,MAP1LC3B,GABARAPL1 |
| 1.265e-03 | -6.67 | CHD8 (chromodomain helicase DNA binding protein 8) | protein interactions | 57680 | 166 | 65 | 19454 | 5460 |
TAF7,NOL4,CTNNB1,AGR2,H2AC4,KPNA1,BRD3,SMAD3,H2AZ1,RCHY1,SPINT2,SUMO2,NKAP,DKC1,EGLN3,CDC5L,MAX,TOP3B,TP53,YIPF4,SOX2,H2AX,IKZF5,NFKBIL1,EZH2,CBX3,ADAMTS1,PSMC3,RUVBL2,H3C1,RUVBL1,KPNA2,BACH1,ASF1A,RIGI,MSH6,MYC,PRPF31,KPNA6,AR,FBXW11,PPIG,CCNF,PELP1,CREB1,FBLN5,AP2M1,PHAX,CSNK2B,PHF21A,MACROH2A1,MAD2L1,ESR2,VIRMA,MAFG,LMNA,RPA2,EPHX1,RPA3,SIRT7,PML,HSPB2,YAF2,KDM1A,COIL |
| 1.265e-03 | -6.67 | SCLT1 (sodium channel and clathrin linker 1) | protein interactions | 132320 | 166 | 65 | 19454 | 5460 |
COMMD6,ATXN10,ARL6IP5,ECHDC1,OCRL,RAB11B,HSBP1,ARL10,SWAP70,MYEF2,AIFM1,SSBP1,MTAP,TES,DRG2,SHC1,SSX2IP,DNAJC7,NDC80,LYPLAL1,MAPK1IP1L,LASP1,AKAP12,ATP1A2,RINT1,PSME1,HINT1,ACTR2,EXOC3,IFT57,GTPBP1,TNRC6C,COMMD8,TBK1,PREB,ERLIN2,TMSB10,ING1,SNAPIN,NECAP2,CTSB,CYB5R3,PHF21A,CHTOP,CCDC22,GLOD4,SNX5,PFDN4,SYCE3,RAB2A,CSK,STAU1,SSR3,YTHDF1,SRSF2,KDM1A,UNC45A,GRPEL1,PEBP1,COMMD2,DCTN3,SDCBP,PAK2,BORCS6,COMMD3 |
| 1.265e-03 | -6.67 | XPC (XPC complex subunit, DNA damage recognition and repair factor) | protein interactions | 7508 | 166 | 65 | 19454 | 5460 |
HMGA1,ERCC3,LSM3,POU5F1,USP15,EMX2,H2BC17,DDX23,POLB,H2AC4,CETN3,CCDC71,H2AZ1,MDM2,MACROD1,CETN2,H2AX,SMAD1,RAF1,TP53,PHF23,SMARCB1,RAD23B,CBX3,H2BC1,COX8A,EMC2,TOP2B,VTA1,SSRP1,H3C1,MRPS33,HMGN4,MYC,MECP2,CHRAC1,CSNK2B,PSMC5,CDC7,TRIM24,PTEN,MACROH2A1,ZNF330,PARP2,ESR2,BTG3,PSMD4,SNRNP40,ZNF428,CDK7,H2BW1,MTF1,MACROH2A2,RPA2,APOBEC3C,SDC2,WRAP53,HSP90B1,RNF146,RPA3,BANF1,XRCC5,COIL,STAU1,HMGB1 |
| 1.265e-03 | -6.67 | NFATC1 (nuclear factor of activated T cells 1) | protein interactions | 4772 | 160 | 63 | 19454 | 5460 |
SATB1,EGR1,RFC2,ATF3,MKLN1,CHAMP1,H2BC1,RBPJ,SMARCB1,SEMA7A,TAF10,TOP3B,TP53,TUBA1A,EGR2,JUN,PPP3R2,ZMYM3,HNRNPL,PRNP,EGLN3,LRWD1,CBFB,DNAJC7,ARMC8,PPP3CA,IFI16,ORC5,HMGA1,HNRNPA1,HDAC3,PIAS1,HSPA5,RFC4,XRCC5,PML,FOS,HDAC5,EP300,CTBP1,CSNK1A1L,ADNP,H2AC7,PRKCA,CSNK1A1,ACTL6A,NEK7,JUNB,CREB1,LIG3,FOXP3,LRRC28,UBE2I,MYC,CREBBP,SMARCA5,ZMYND19,IKZF2,RFC5,RUNX1,SMARCE1,ATF1,TUFM |
| 1.265e-03 | -6.67 | CTSD (cathepsin D) | protein interactions | 1509 | 160 | 63 | 19454 | 5460 |
NME1,CTSA,DISC1,EZH2,RNF8,PPME1,B3GNT2,EEF1A1,H2AX,ETFA,G3BP1,HUWE1,MPST,PABPC1,SCYL2,BGLAP,AGR2,IGFBP4,CST3,DPP4,PRDX1,IFI16,ATP1B1,HNRNPA1,ACTA2,FUBP3,SPRED2,CD4,HSP90B1,METTL14,PPT1,RPA2,PIH1D1,CCL21,CFTR,IGFBP3,CSTB,TMEM106B,DDX39B,RPA3,BAP1,JADE1,RAB5A,HSPB2,DCAF4,YWHAZ,UBE2H,ILK,SERPINH1,SFN,CUL2,LDHB,MYC,LDHA,CTSB,ESR2,APEX1,SUCLG2,PLP1,UQCRC2,MSN,SEC61B,CALML5 |
| 1.267e-03 | -6.67 | rhythmic process | biological process | GO:0048511 | 270 | 103 | 18204 | 5365 |
NUDT12,CSNK2A1,CYP1B1,GAS2,CARTPT,BMPR1B,NFYA,MAP2K6,NPPC,PTEN,PSPC1,TOP1,GPR176,PML,CIART,PPP1CC,CRY1,FBXW11,TYMS,OPRL1,ADNP,HLF,NPY5R,KCND2,DHX9,CLDN4,DYRK1A,KLF10,SIAH2,TGFB3,CDK5,FBXW7,PRMT5,KDM2A,PIWIL2,CREBBP,BHLHE40,PROX1,DRD3,MAPK10,CCAR2,EP300,ADIPOQ,TNF,TGFB2,ROCK2,HNRNPD,NPR2,AANAT,PCNA,TEF,ADAMTS1,OXTR,CA12,ATG7,HDAC3,SUV39H1,PGR,CIPC,SP1,OPRK1,NTRK2,PPARG,FZD4,PTN,GFPT1,PPP1CB,SIN3A,SLC6A4,EGR1,MSTN,EZH2,ID1,SRC,CDK1,KLF9,CBX3,HSPA8,HOMER1,HUWE1,NFIL3,PPARA,CDK5R1,HEBP1,NONO,ATF4,LEP,RORB,THRAP3,FBXL3,DTL,F7,TP53,UBE3A,NLGN1,TNFAIP6,CSNK1E,USP2,ID4,CREB1,IGF1R,DDX5,LGR4 |
| 1.269e-03 | -6.67 | Mitochondrial carrier domain | gene3d domains | 1.50.40.10 | 53 | 26 | 14470 | 4137 |
SLC25A5,SLC25A10,SLC25A20,SLC25A28,MTCH2,SLC25A14,SLC25A21,SLC25A51,SLC25A46,SLC25A4,SLC25A44,SLC25A3,SLC25A42,UCP2,SLC25A17,SLC25A32,SLC25A45,SLC25A26,SLC25A27,SLC25A12,SLC25A39,SLC25A23,SLC25A24,SLC25A1,SLC25A31,SLC25A11 |
| 1.273e-03 | -6.67 | positive regulation of autophagy | biological process | GO:0010508 | 153 | 63 | 18204 | 5365 |
RALB,SH3BP4,VDAC1,ORMDL3,TRIM34,HMGB1,STUB1,RB1CC1,STK11,MTDH,TRIM21,TFEB,C9orf72,WDR45,ADRB2,TRIM5,SQSTM1,PLEKHF1,PAFAH1B2,TRIM68,GNAI3,SNX18,IFNG,SVIP,CCNY,ATG16L1,DAPK1,ATG101,LACRT,TRIM6,TOM1,TRIM8,ROCK1,SESN3,TRIM32,TP53INP1,SLC25A4,FLCN,BAG3,SESN2,IL4,TLR9,TRIM22,CSNK2A1,HSPB8,TBK1,TMEM59,BECN1,PIP4K2C,UFL1,SH3GLB1,SUPT5H,TICAM1,FBXO7,IFNB1,BNIP3L,BAD,TRIM23,SLC25A5,OPTN,PIM2,RNF152,GSK3A |
| 1.277e-03 | -6.66 | positive regulation of leukocyte cell-cell adhesion | biological process | GO:1903039 | 279 | 106 | 18204 | 5365 |
IL12B,SLC7A1,IFNG,ACTL6B,CD47,PIK3CA,CCL5,CD86,IL6,IL21,CSK,BCL10,HSPD1,CD274,SRC,FOXP3,IL12A,DHPS,LILRB1,ACTL6A,NKAP,SASH3,PNP,IL18,CD83,THY1,SMARCE1,KLHL25,LEP,CD40LG,BTN2A2,IL6ST,ST3GAL4,PTPN11,WNT10B,SMARCB1,EPO,IL15,CAV1,IL7,IL23A,CBFB,CD80,B2M,CD28,PRKCQ,ZBTB16,IL4,SMARCD3,RUNX1,SOCS5,CD4,MIR21,MIR30B,CD81,LILRB4,CD46,IL1A,XCL1,IGF1,ACTB,EP300,TNF,CD209,VSIR,IL2RG,YES1,TFRC,SELENOK,NCK1,RPS3,GPAM,TESPA1,BCL6,AKT1,IL1B,CD1D,SYK,HMGB1,PPP3CA,AGER,PYCARD,DUSP10,CCR7,ICOS,IL2RA,TNFRSF14,JAK2,CCL2,BAD,RAG1,TRAF6,NLRP3,CHST2,XBP1,CCL21,CYRIB,PDCD1LG2,RHOH,DPP4,CCL19,AIF1,EFNB1,TGFBR2,CCR2,IL2 |
| 1.277e-03 | -6.66 | SIGMAR1 (sigma non-opioid intracellular receptor 1) | protein interactions | 10280 | 107 | 45 | 19454 | 5460 |
CCNF,S1PR4,LMBR1L,GPR173,ACAT1,RETREG3,VIRMA,APLNR,OPRM1,GPR17,VEZT,CGRRF1,SAYSD1,TSPAN15,TMEM106B,RPA3,CXCR4,SLC35F2,HSPA8,TACR1,VIPR1,RER1,LPAR1,SRI,HSCB,RABL3,CFTR,STOM,RPA2,CD63,HSD17B11,ARL6IP5,HNRNPL,TMEM208,ATP5MG,MOV10,AK2,SLC2A1,RNF139,PLSCR1,TMEM87A,RIGI,YIPF3,KDELR1,CCR1 |
| 1.283e-03 | -6.66 | positive regulation of nucleocytoplasmic transport | biological process | GO:0046824 | 62 | 30 | 18204 | 5365 |
LEP,CAMK1,PSEN1,SFN,HSP90AA1,DHX9,CTDSPL2,BAG3,JUP,DMAP1,IL1B,ANP32B,CDK1,RIOK2,RAN,PIK3R1,RBM22,NRDE2,PIK3R2,HDAC3,NCBP2,HYAL2,EFCAB7,SMAD3,MAVS,IFNG,EP300,MDM2,JAK2,HCLS1 |
| 1.286e-03 | -6.66 | NDUFAF5 (NADH:ubiquinone oxidoreductase complex assembly factor 5) | protein interactions | 79133 | 87 | 38 | 19454 | 5460 |
AUH,MTRF1,MTG2,GRSF1,PMPCA,PFDN5,KLHL22,CBR4,RHOG,MRPS26,SNX5,CCDC90B,GATD3,MRPL23,STARD7,GRPEL2,NDUFAF4,RMND1,LIAS,NDUFAB1,DHRS4,NDUFAF3,METTL2A,HBB,PDHA1,NDUFS3,KLC2,MTRES1,ACACA,BOLA3,HSPD1,ATP5F1E,HINT2,COX8A,GFM1,HSCB,FASTKD5,IMMP2L |
| 1.286e-03 | -6.66 | LIMCH1 (LIM and calponin homology domains 1) | protein interactions | 22998 | 87 | 38 | 19454 | 5460 |
TRMT61A,APEX1,DYRK1A,VIRMA,HNRNPL,ACTB,YES1,FBXO22,GABPA,XPO1,HDAC6,YWHAH,BTF3,AR,CTNNB1,MYC,STK38L,ZDHHC15,KPNA1,KLHL15,BAP1,ZYX,RPA3,GNB4,CAPZA1,IFNG,RFC2,HUWE1,TNF,ISG15,DDX39A,OTUD6B,PPP1CB,CFTR,RAF1,CCND1,RPA2,CAPZA2 |
| 1.286e-03 | -6.66 | UBE2G2 (ubiquitin conjugating enzyme E2 G2) | protein interactions | 7327 | 87 | 38 | 19454 | 5460 |
RNF146,ACACA,TPT1,UBL4A,CCDC47,DNAJC25,MLLT6,CDC42,SEM1,HSCB,ERLEC1,RNF5,HNRNPDL,RNF26,VAMP8,PDE2A,RNF167,TRIM3,UBE3A,TRIM21,RC3H2,KDM2A,FBXW11,MUL1,USP15,CBL,HNRNPD,RNF139,HNRNPAB,CUL3,BAG3,POLR3F,MDM2,EGLN3,TMEM45B,UBE2G2,PHB1,DUSP6 |
| 1.291e-03 | -6.65 | CALML3 (calmodulin like 3) | protein interactions | 810 | 227 | 85 | 19454 | 5460 |
LIG3,SCAMP2,QSER1,TMEM74,GABPA,ELMO1,SCN3B,SUGP1,MYC,NAA50,FMC1,ISCA2,PPP1CC,LDB1,FBXO44,BTF3,ARHGAP21,CSGALNACT1,MAPRE1,PML,DCTN6,FOS,FLYWCH2,ACTMAP,HMCES,HSPA8,SLC37A4,NT5C3A,FBXL4,TANK,SF3A1,SSBP2,FTH1,DUSP22,NUDT3,CFTR,KDELR2,PPP1CB,STX17,SKA2,ARL15,E2F6,EIF4E2,EHBP1,GNPAT,OR51E2,TCEAL8,NRSN1,CX3CL1,VTI1B,RAB11B,FUNDC2,PTDSS1,EMC4,ERCC3,MAPK4,HNRNPA1,AGPAT1,USP15,UPK1A,TNNC2,BHLHE40,FSTL1,FBXO3,SEMG2,EPHA4,CAMK2G,ERLEC1,RNF115,RAD21,CFAP97D1,KHDC4,HSDL2,FCF1,HINT3,ESS2,CAPZA2,IK,JOSD1,TMEM31,CAMK1,EZH2,SGIP1,RNF8,CCR1 |
| 1.291e-03 | -6.65 | FOXK1 (forkhead box K1) | protein interactions | 221937 | 227 | 85 | 19454 | 5460 |
YWHAZ,ATP1A1,BRMS1,AR,BTF3,ESR2,VIRMA,APEX1,FBLN5,ELK3,ZNF330,IRF2,PTEN,ING2,PRMT5,KLF3,LMNA,AGGF1,CTBP1,PAX9,NUDT3,ZNF428,KLF12,FAXC,RFXANK,TGIF2LX,ZBTB39,PYGB,METTL22,COIL,PML,POLD2,PPM1G,RPA3,TEX264,DVL2,BAP1,EP300,HSPA8,LHX2,YWHAB,UBXN6,KARS1,GSTM3,DYRK1B,YWHAH,XPO1,YWHAG,BRMS1L,PRNP,KLF9,NUP35,MBD5,EGLN3,CACYBP,KIAA0513,EEF1AKMT3,SIN3A,TRAK2,RB1,GATAD1,TBC1D4,TP53,CCT5,TOP3B,MAX,KBTBD4,ELF1,TULP3,EEF2,SAP30,SOX2,ING1,RBBP7,PSMA1,PAX6,ABHD10,RIGI,AHCYL1,CAPZA1,PABPC1,DDR1,BAG2,FHL3,RABGGTB |
| 1.293e-03 | -6.65 | TMED4 (transmembrane p24 trafficking protein 4) | protein interactions | 222068 | 73 | 33 | 19454 | 5460 |
CHCHD6,TMED9,SPCS1,LMAN1,ESR2,B4GAT1,MOV10,TMED5,SCN3B,GORASP2,CDK5RAP3,PPIC,TIAM1,RPA3,RAB1A,PEBP1,FGF3,LGI1,TMEM106B,EMC2,SLC7A14,EMC1,TMED3,SRPRB,TMED7,RAF1,NUP62,TMEM59,YIPF5,SEC62,RPA2,PDHA1,SLC25A3 |
| 1.295e-03 | -6.65 | ZCCHC7 (zinc finger CCHC-type containing 7) | protein interactions | 84186 | 62 | 29 | 19454 | 5460 |
PHC1,RPLP0,SUMO1,RPL4,DGCR8,H1-6,RPL28,ZKSCAN1,PPAN,SNIP1,RPL3,CPNE2,DCAF4,RPL10A,MPHOSPH6,NOL12,RPL7A,CREBBP,ZNF250,SUMO2,SNRNP40,TENT4A,ZNHIT6,RPL8,SRP14,SENP5,UBE2I,PRKRA,EIF2S2 |
| 1.295e-03 | -6.65 | AKR7A2 (aldo-keto reductase family 7 member A2) | protein interactions | 8574 | 62 | 29 | 19454 | 5460 |
DCTN3,IGF1R,ACTR1B,PCNA,BIRC2,DCTN6,BAP1,MSH6,PSMC1,TRIM63,TOLLIP,HSCB,ACTR1A,TBK1,AKR7A2,PTPN22,TFCP2,PLAA,DCTN4,ACAT1,MCPH1,CFAP298,MTM1,TXN,RALA,MTMR12,CCNB1,F2,ARMT1 |
| 1.295e-03 | -6.65 | RNF128 (ring finger protein 128) | protein interactions | 79589 | 62 | 29 | 19454 | 5460 |
WWP2,CTNNB1,SLC30A5,HFE,SDF2L1,UBE2D1,HAX1,UBE2H,PTK7,WDR6,UBE2N,RNF128,SLC39A10,UBE2I,SNX17,CD40LG,STK3,TBK1,TP53,DDX39A,TMEM59,TFRC,SSR1,AAMP,CD83,ITM2B,APPBP2,UBE2D3,USP8 |
| 1.295e-03 | -6.65 | USP49 (ubiquitin specific peptidase 49) | protein interactions | 25862 | 62 | 29 | 19454 | 5460 |
SLC39A7,BAG2,HADHA,PPM1G,MCM6,HUWE1,RUVBL1,MSX1,RBCK1,DUSP1,H2AX,TP53,PAX9,EZH2,RPN1,PSMC5,CETN3,APOBEC3G,KRR1,PPP5C,CETN2,TRIM35,MED17,SHPRH,CTNNB1,F7,STAMBPL1,DICER1,IVNS1ABP |
| 1.295e-03 | -6.65 | PDE6D (phosphodiesterase 6D) | protein interactions | 5147 | 62 | 29 | 19454 | 5460 |
TF,KRAS,SKP1,RAB18,RAB13,LMNA,NIM1K,SERPINA1,ARL15,UBL3,RAP1A,INPP5E,TXNL4A,SERPINA3,CDC42,IRF2BP1,RAB28,HRAS,ALB,CETN3,LMNB1,RHOB,SMAD4,FAM219A,YWHAB,RAP2B,HP,COPS5,RHEB |
| 1.296e-03 | -6.65 | purine nucleotide metabolic process | biological process | GO:0006163 | 455 | 164 | 18204 | 5365 |
OLA1,EPHA2,PGAM1,ABHD14B,FMO1,PDE8A,PPAT,LDHA,NDUFA1,FKRP,PFKFB2,SULT1A3,NDUFA5,GTPBP1,NME2,PDHB,ATP5MK,ATP5MG,PPT1,SARM1,UCP2,RPIA,UQCC3,PDE1A,NT5C2,ATP5PD,NUDT2,PRPS1,ATP5F1B,NPR2,GPAM,ATP5PF,TECR,ENTPD4,G6PD,TPST1,PDHA1,NUDT12,CD38,ACOT8,DLG1,MVD,RPE,NDUFA2,ACAT1,BPGM,ATP1A2,ATP1B1,TP53I3,SDHB,PTHLH,DNPH1,NUDT9,PDE2A,ELOVL6,NPPC,CLPX,ACACA,IDH1,ELOVL1,BAD,DCK,NUDT3,GUCY1B1,ADCY2,CACNB4,ATP5MC1,ATP5F1D,NDUFB5,HSPA8,ACSS2,DLAT,ENO1,HTR2A,NDUFAB1,NDUFB10,PNP,ATP5F1A,NME1,MTHFD2L,NDUFS8,IDH2,MPP1,GPD2,GLYAT,ENO2,PDE4B,ATP5MC3,SULT1B1,NDUFB7,COX11,NDUFA12,PDE7A,HACD2,GMPS,ADK,SUCLG2,GNAI3,NDUFS2,MMUT,IDO1,NUDT18,FITM2,NUDT4,ACSL4,DNAJC30,STOML2,ATP5PB,NMRK1,RAB23,ELOVL3,FMO2,CASK,SLC25A1,DLST,FHIT,ALDH1L1,NDUFV2,IER3,PGM1,NDUFB6,GUK1,OGDHL,MFN1,NDUFC2,NDUFS6,PRPSAP1,PDE9A,SDHC,NUDT5,RAN,NQO1,PCK2,NUDT7,PAPSS2,NDUFB8,MDH1,AK5,LIPA,ELOVL4,ATP5PO,PGK1,AK2,ELOVL7,HACD1,GAPDH,NUDT16,DCAKD,NDUFB4,HINT1,ATP6V1A,ADCY3,ADSS2,PC,NDUFS3,ACOT6,FAR2,SAMHD1,AK3,ATP5F1E,HMGCS1,NME4,LDHB,NUDT19 |
| 1.297e-03 | -6.65 | RAB4A (RAB4A, member RAS oncogene family) | protein interactions | 5867 | 451 | 156 | 19454 | 5460 |
ROCK1,GARIN6,RAB14,PNP,LDHA,SNX3,WDR45,STX10,RPS3,VAMP3,SMAP2,NECTIN2,NRP1,EPHA2,ARFGAP3,DEPDC1B,EXOC5,GORASP2,RAB2A,SLC7A1,YKT6,MAVS,RTN4,ARFIP1,RAB33B,PRDX6,RPA3,IDH3A,VPS54,HEXIM1,LEMD3,AP1AR,RPA2,CDK1,FGFR1,SLC12A2,VIPAS39,USE1,GOLGA5,CDC42,CD2AP,SYNRG,RPS14,RABL3,TPRA1,ARHGAP1,PDCD1LG2,SLC38A2,TMPO,STX6,LMAN1,CAV1,VTI1B,RPL35A,RAP1B,SLC39A10,CDCA3,SRPRA,RPL12,PTPN1,EHBP1,CAMLG,OSBPL8,POR,ESYT1,HM13,TMEM199,PGAM1,APBB3,CTNND1,ARF4,SLC6A8,SRPRB,SHISA2,SNAP23,NSDHL,RAB1A,STX8,SOD2,TFRC,EXOC3,UBIAD1,CCDC47,PREB,SNAP29,TP53,CLIC4,APEX1,ACTB,DYNLL1,FAM83B,FAM91A1,ARF1,RAN,RPS5,SLC38A1,LAMTOR1,CD226,LMNB1,CAPG,BAG3,VEZT,RAB11A,LDHB,STX7,TRA2B,SLC31A1,PHB2,GRPR,RABAC1,RAB5A,AKAP1,EXD2,CNDP2,VAPB,TMEM115,VPS18,MTMR6,TOR1AIP2,PGRMC1,NOTCH2,VAMP7,KIF3B,OCRL,AFTPH,SNX2,SPTAN1,SNX1,STX5,PHB1,COTL1,RPL23,CDK5RAP3,WDR11,TBC1D5,DDRGK1,VAMP8,SEMA4C,SLC20A2,EFNB1,TMEM87A,SCYL2,RPS11,ITGB5,STX12,VAMP2,VPS33A,STIM1,GDI2,RAB6B,FAF2,MACO1,STBD1,RAF1,TPD52,ARFGEF1 |
| 1.303e-03 | -6.64 | Longin | smart domains | SM01270 | 5 | 5 | 9717 | 2575 |
VAMP7,YKT6,SEC22B,SEC22C,SEC22A |
| 1.304e-03 | -6.64 | ARHGAP24 (Rho GTPase activating protein 24) | protein interactions | 83478 | 480 | 165 | 19454 | 5460 |
PYGB,UNC45A,FXR2,UFL1,GPHN,HSPA8,DDX5,CCDC86,XRCC5,EIF4B,USP39,PRDX3,POLR2B,NCKAP1,SSH3,STAT1,MATR3,ACTB,TUBB,GGT7,PRMT5,ENO2,RPS5,HSP90AA1,CKB,CCT2,LMNB1,PSMD1,MCM3,MCM4,NIBAN2,ACO2,LDHB,CUL2,PAPOLA,CUL3,RPS27A,MCM6,AHCYL1,SSRP1,G3BP1,HSPD1,ABCF1,PABPC1,CCT8,RPN1,PLS3,H2BC1,TUBA1A,PPP2R1A,ACTN4,GFPT1,H1-3,EEF2,KIF2A,NAA15,TRMT1L,RANBP1,ACO1,CCT7,DHX15,HSP90AB1,HNRNPL,CCAR2,OSBP,CORO1C,HP1BP3,GYS1,DDX1,AK2,H2BC17,HBA1,XPO1,PPIB,EIF3D,CTNNB1,CLPX,PSMD3,DDX50,LAMP2,DPY30,DIRAS2,BRIX1,HSPA5,MARS1,GTF2I,RPL4,H2BC12,DLAT,ZNF319,PAX9,RARS1,ZNF501,H2BC11,LMNA,P3H1,JUP,HBB,WWP1,HSP90B1,GTF3C4,UBA52,ROCK1,DEK,SEC63,LDHA,GANAB,ACAT1,ALB,PSPC1,TUBA1B,CTTN,ENO1,ATP1A1,XPOT,IGF2BP1,COL1A2,DNAJC10,CFL1,ATP5F1A,H2BC9,NONO,NCAPG2,USP14,TUFM,SMARCA5,MAT2A,CARS1,RNF20,OLA1,H2BC14,HNRNPK,HSPE1,CSE1L,ABCE1,SLC16A1,PPP1R12A,NKRF,KATNAL1,VAC14,GFM2,TFRC,NEFL,GTPBP8,EEF1A1,PGM1,RRM1,CCT5,G6PD,SURF6,MIOS,CAND1,TOP1,SEC23A,SYNCRIP,STT3A,SSBP1,AIFM1,AKAP8L,NME2,SNRNP70,GAPDH,MOV10,RIT2,TLE1 |
| 1.308e-03 | -6.64 | DAXX (death domain associated protein) | protein interactions | 1616 | 349 | 124 | 19454 | 5460 |
HDAC3,PIAS1,NHP2,CXXC1,UTP23,GID8,PML,HSPB2,SQSTM1,H2BC11,SNAI2,TFIP11,RPL26L1,SUMO1,MX1,FAXC,FTH1,DAPK3,TRIM54,PLAGL1,CDC20,DEK,STUB1,CREB1,RPS3,TRIM27,CSNK2B,UBE2I,SPIN3,PTEN,SPOP,PDCD4,SMARCA5,CEP70,AR,H3C1,IMP4,MSANTD4,NOC4L,TGFBR2,SRSF12,RIGI,RPL23A,CBX3,CHAMP1,DMAP1,ZBTB26,TP53,MLLT6,MAP1LC3B,FZR1,RPS16,BRMS1L,DKC1,MDM2,ZBTB2,KRR1,PRR3,SMAD4,H2AC4,NOL12,SSX2IP,BRD3,CMSS1,CSNK2A1,SUV39H1,STAU1,GPC1,COIL,ZDHHC17,TRIM5,CCDC86,TERT,EP300,ADNP,H1-5,CA12,TAX1BP1,CBX5,MAD2L1,TNPO3,APEX1,RPL19,PNMA1,UBE2S,EIF3K,ZMYM2,FAS,ZCRB1,COP1,NSA2,H1-1,MYC,CREBBP,CUL3,RBBP7,CDCA7L,RFC2,RFC3,SSRP1,ABCF1,TOP2B,TRIM21,FASLG,MAX,JUN,SUMO3,SUMO2,PPIA,SIN3A,SDC4,TSG101,HP1BP3,ZCCHC9,HBA1,RPL23,HSPB1,BAZ1B,ZCCHC10,DPY30,XPO1,TRIM34,STK4,GAS8 |
| 1.308e-03 | -6.64 | LZTR1 (leucine zipper like post translational regulator 1) | protein interactions | 8216 | 110 | 46 | 19454 | 5460 |
TCF19,SHOC2,NUDT12,WWP1,PPP1CB,MYH1,GABARAPL2,AATF,TRIM5,POLR1B,RIT1,CKB,MCM3,CUL3,POLR2B,TAF11,PYGM,STAT1,TXN,EIF4A3,CAPN2,MAP1LC3B,RAF1,TOP3B,KBTBD4,CNOT6L,VTA1,RERE,CHMP1B,KRAS,RUVBL1,SCYL2,PLSCR1,ZNF451,VPS4A,ZNF175,BRD3,ATG7,IFI16,BMPR1B,RIT2,CAND1,MRAS,MYBL2,HCLS1,HRAS |
| 1.311e-03 | -6.64 | Toll Like Receptor 10 (TLR10) Cascade | REACTOME pathways | R-HSA-168142 | 84 | 40 | 10285 | 3229 |
DUSP3,SKP1,HMGB1,TRAF6,IKBKB,NFKBIA,MYD88,MAP2K3,MAP2K1,MEF2C,PPP2R1A,PELI1,PELI3,UBB,RPS27A,UBA52,TLR10,MAPKAPK3,MAP2K6,ELK1,ATF1,TAB2,NFKBIB,CREB1,UBE2N,S100B,DUSP6,TAB1,MAPK10,FOS,TLR5,UBE2V1,AGER,JUN,IRAK4,NFKB1,PPP2CB,DHX9,MEF2A,FBXW11 |
| 1.311e-03 | -6.64 | MyD88 cascade initiated on plasma membrane | REACTOME pathways | R-HSA-975871 | 84 | 40 | 10285 | 3229 |
MAPKAPK3,MAP2K6,ELK1,ATF1,TAB2,NFKBIB,CREB1,UBE2N,S100B,DUSP6,TAB1,MAPK10,FOS,TLR5,UBE2V1,JUN,AGER,IRAK4,NFKB1,PPP2CB,DHX9,MEF2A,FBXW11,DUSP3,HMGB1,SKP1,TRAF6,IKBKB,NFKBIA,MYD88,MAP2K3,MAP2K1,MEF2C,PPP2R1A,PELI1,UBB,PELI3,RPS27A,UBA52,TLR10 |
| 1.311e-03 | -6.64 | Toll Like Receptor 5 (TLR5) Cascade | REACTOME pathways | R-HSA-168176 | 84 | 40 | 10285 | 3229 |
MAPKAPK3,MAP2K6,TAB2,ELK1,ATF1,CREB1,NFKBIB,UBE2N,DUSP6,S100B,MAPK10,TAB1,FOS,TLR5,AGER,JUN,UBE2V1,IRAK4,PPP2CB,NFKB1,DHX9,MEF2A,FBXW11,DUSP3,HMGB1,SKP1,TRAF6,IKBKB,MYD88,NFKBIA,MAP2K3,MAP2K1,MEF2C,PELI1,PPP2R1A,PELI3,UBB,RPS27A,TLR10,UBA52 |
| 1.312e-03 | -6.64 | Ubiquitin_CS | interpro domains | IPR019954 | 10 | 8 | 18521 | 5414 |
UBL4A,USP14,UBB,NEDD8,RPS27A,UBFD1,UBA52,FAU |
| 1.315e-03 | -6.63 | papilloma | COSMIC cancer mutations | papilloma | 35 | 19 | 16828 | 4835 |
STK11,GNAQ,HRAS,KRAS,PIK3R1,IDH1,FGFR1,PIK3CA,PTEN,NTRK3,MET,KIT,GNA11,CTNNB1,TP53,JAK2,AKT1,IDH2,FBXW7 |
| 1.315e-03 | -6.63 | breast-hyperplasia-columnar_cell_lesion | COSMIC cancer mutations | breast-hyperplasia-columnar_cell_lesion | 35 | 19 | 16828 | 4835 |
TP53,MET,KIT,GNA11,CTNNB1,IDH2,FBXW7,PTPN11,JAK2,AKT1,PIK3CA,FGFR1,NTRK3,HRAS,KRAS,PIK3R1,IDH1,MAP2K1,GNAQ |
| 1.315e-03 | -6.63 | columnar_cell_lesion | COSMIC cancer mutations | columnar_cell_lesion | 35 | 19 | 16828 | 4835 |
TP53,GNA11,MET,KIT,CTNNB1,IDH2,FBXW7,JAK2,PTPN11,AKT1,PIK3CA,FGFR1,NTRK3,HRAS,KRAS,PIK3R1,IDH1,MAP2K1,GNAQ |
| 1.315e-03 | -6.63 | breast-hyperplasia-ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | COSMIC cancer mutations | breast-hyperplasia-ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | 35 | 19 | 16828 | 4835 |
NTRK3,PTEN,PIK3CA,FGFR1,FBXW7,IDH2,AKT1,JAK2,PTPN11,TP53,CTNNB1,KIT,GNA11,MET,GNAQ,IDH1,PIK3R1,KRAS,HRAS |
| 1.315e-03 | -6.63 | ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | COSMIC cancer mutations | ductal_epithelial_hyperplasia-hyperplasia_of_usual_type | 35 | 19 | 16828 | 4835 |
KRAS,HRAS,IDH1,PIK3R1,GNAQ,CTNNB1,MET,KIT,GNA11,TP53,AKT1,PTPN11,JAK2,FBXW7,IDH2,FGFR1,PIK3CA,PTEN,NTRK3 |
| 1.320e-03 | -6.63 | CUTA (cutA divalent cation tolerance homolog) | protein interactions | 51596 | 46 | 23 | 19454 | 5460 |
TF,REXO2,RIGI,GID4,SOD1,IDH1,PRKAG1,CDK1,EZH2,ZER1,SOD2,E2F4,PRKAB1,RAF1,SPPL3,UBB,MTAP,CHRAC1,HTRA2,MDH1,ARMC8,OAT,HNRNPD |
| 1.320e-03 | -6.63 | CCNY (cyclin Y) | protein interactions | 219771 | 46 | 23 | 19454 | 5460 |
DUSP22,COMTD1,CENPM,E2F4,DHRS3,NUPR1,EFNB1,ABCE1,TMEM185A,KRAS,CERS2,YWHAG,YWHAH,MYC,YWHAB,FYTTD1,MED21,ATG3,YWHAZ,RHOB,HRAS,ESR2,HNRNPL |
| 1.320e-03 | -6.63 | MFN1 (mitofusin 1) | protein interactions | 55669 | 46 | 23 | 19454 | 5460 |
FUNDC2,ESR2,MFN1,CSK,MARCHF5,CCNB1,BAK1,SLC25A46,GPR17,EDEM1,AKAP1,EP300,MAVS,TLR4,KRAS,NPTN,HCST,FAF2,MIEF1,TOMM22,ILF2,MOB3C,SAMM50 |
| 1.320e-03 | -6.63 | Cdc16 (CDC16 cell division cycle 16) | protein interactions | 69957 | 46 | 23 | 19454 | 5460 |
ANAPC11,ANAPC16,NEK2,ANAPC13,YIPF5,GNPTG,CDK17,FZR1,CLIC4,MAD2L1,CDC20,HOMER1,HOMER3,NDUFB4,ANAPC2,GGCX,ANAPC4,CDC23,CDC26,PYCR1,PYCR2,CDC16,ANAPC15 |
| 1.325e-03 | -6.63 | response to L-glutamate | biological process | GO:1902065 | 16 | 11 | 18204 | 5365 |
TNF,KCNB1,TMBIM6,AMIGO1,AIFM1,PCNA,IGF1R,HPCA,UFL1,TAF9,TUBA1A |
| 1.325e-03 | -6.63 | regulation of response to drug | biological process | GO:2001023 | 16 | 11 | 18204 | 5365 |
MIR873,MIR34B,MIR495,MIR186,MIR133B,SUFU,MIR185,MIR129-1,MIR1-1,GRM2,MIR9-1 |
| 1.325e-03 | -6.63 | estrous cycle | biological process | GO:0044849 | 16 | 11 | 18204 | 5365 |
OPRK1,IGF1R,PCNA,OPRL1,PTN,ADNP,OXTR,CA12,EGR1,CYP1B1,HSPA8 |
| 1.325e-03 | -6.63 | locomotory exploration behavior | biological process | GO:0035641 | 16 | 11 | 18204 | 5365 |
MYG1,TNR,NLGN2,UBE3A,DPP4,PRKCE,CRBN,ATP1A2,SLC4A10,TUBA1A,DLG4 |
| 1.336e-03 | -6.62 | MIA3 (MIA SH3 domain ER export factor 3) | protein interactions | 375056 | 218 | 82 | 19454 | 5460 |
NXPH3,GGH,DNAJC10,SPCS3,SDF2L1,CALU,SCFD1,SMAP2,LMBR1L,GXYLT1,SEC61B,TRIM27,RMDN3,GSK3A,TAX1BP1,CTSB,ESR2,VIRMA,ST7,SEC62,CNPY3,TMEM106A,FGFR1,VPS18,SSR1,P3H1,RPA2,TMEM106B,DNAJC3,RPA3,RAB9A,DERL1,MIA2,RAB5A,SPCS2,AKAP1,FXR2,HSPA5,STX7,TOMM20,PXMP2,SLC25A46,CFC1,MARCHF5,NDC80,SAV1,DPP4,AGR2,ESYT1,CRTAP,HOMER3,PTPN1,SEC23A,KRT8,HSD17B11,GJA1,HNRNPL,DNAJB9,DNAJC1,TMPO,STX6,LMAN1,KBTBD4,SERPINA3,DNAJC25,RAB4A,RPN1,HSPA13,STIM1,MOB3C,SERPINA5,NCR3,TMT1A,TMEM87A,CYP2C9,IGF1R,SEC11A,EWSR1,SLC39A7,DNAJC30,SRPRB,FKBP8 |
| 1.337e-03 | -6.62 | CDK20 (cyclin dependent kinase 20) | protein interactions | 23552 | 113 | 47 | 19454 | 5460 |
FKBP8,RIGI,TRAFD1,CDK5,NDUFS3,RAF1,EEF2,LBR,TUBA1A,MAP2K3,NOP58,FZR1,HSP90AB1,PSMB5,WDR6,MAGED2,AK2,HAX1,AHSA1,CDK12,FTL,PRIM2,RLIM,HSPA8,GTF2IRD1,TCP11L1,WRAP53,HEXIM1,NTPCR,CDK7,TIMM13,CCNH,RBBP4,TUBB,YES1,POLR2B,PPP5C,UBE2S,STUB1,CSNK2B,GGT7,RPS6KA4,HSP90AA1,ATP1A1,CFAP20,PSMB2,PSMD1 |
| 1.341e-03 | -6.61 | BRAP (BRCA1 associated protein) | protein interactions | 8315 | 90 | 39 | 19454 | 5460 |
SMARCE1,FBXO7,RNF40,BRAP,CUL3,TRIM8,PPP2R5A,CUL2,UBE2H,USP15,IKBKB,BRCA1,PPP2R5E,HRAS,STUB1,RCHY1,NFKBIB,UBB,UBE2L3,EGLN3,HMG20A,CAND1,DCUN1D1,TRAF2,ISG15,CDKN1A,RBM12,RAF1,KBTBD4,OTULIN,RPA2,ZNF526,MAP2K1,DNAJC2,SYVN1,EFHC1,RPA3,RNF20,NEDD8 |
| 1.341e-03 | -6.61 | CEP126 (centrosomal protein 126) | protein interactions | 57562 | 90 | 39 | 19454 | 5460 |
FAM118B,PDCD5,EIF2S2,LRRC1,PRKRA,NAP1L5,RAN,FEZ1,TNFRSF14,YAE1,GSTO1,YWHAZ,ROGDI,GPRASP2,HMOX2,PPP1CC,CSK,ZNF24,PIK3R3,PFDN1,TOMM20,SNRPG,NAT9,RGS2,TFG,TTR,NPM3,THRAP3,RUVBL1,RAB27A,SAT1,RBM23,RETREG2,GEMIN7,RPA2,DISC1,MAD2L1BP,DDX39A,ING5 |
| 1.341e-03 | -6.61 | SIAH2 (siah E3 ubiquitin protein ligase 2) | protein interactions | 6478 | 90 | 39 | 19454 | 5460 |
PPP1CC,AR,SIAH2,USP13,OPRM1,XAF1,SYP,UBE2D1,RBBP8,UBE2I,TES,CD274,UBE2N,DLST,UBE2V2,CACYBP,EGLN3,PEG10,EAF2,PSMD4,CCAR2,EGLN2,SIAH1,TRAF2,TOP3B,DYRK2,NFE2L2,OPRK1,AKAP1,EP300,MYD88,ZYX,PPP1R12A,PML,PIAS1,PIWIL2,HSPA5,HDAC3,UBE2D3 |
| 1.341e-03 | -6.61 | MED7 (mediator complex subunit 7) | protein interactions | 9443 | 90 | 39 | 19454 | 5460 |
ESR2,POLR2B,TRIM15,POLR2I,MED17,TRIM29,UBE2I,CAB39,THOC2,MED4,MED29,ATG3,MED27,MED10,MED21,MED22,RUVBL1,KRAS,FXR2,MED11,MED13L,INO80C,PML,MED31,HGS,POLR2G,POLR2C,MED23,CDK8,ZSCAN1,ELP3,DDX39A,MED30,RPAP2,MED9,VDR,ACTL6A,ATG16L1,RBFOX2 |
| 1.341e-03 | -6.61 | FGFR1OP2 (FGFR1 oncogene partner 2) | protein interactions | 26127 | 90 | 39 | 19454 | 5460 |
SURF4,TOX4,LMNA,STOM,GIT2,DCUN1D5,PPP2R1A,METTL15,CYFIP2,CAMK2G,KDM4B,PHB2,VDAC1,CCT8,SIKE1,STK26,EP300,STK24,SP1,CCHCR1,PDCD10,DDX1,ISCA2,STK4,SLMAP,NCKAP1,CAV1,STK3,TNIK,PLP1,ALYREF,PPP2CB,TRAF3IP3,PHB1,PSMC5,TRAF7,RMDN3,MOB4,GANC |
| 1.341e-03 | -6.61 | SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2) | protein interactions | 6655 | 54 | 26 | 19454 | 5460 |
GLO1,NOP16,PDIA3,CREBBP,SERPINH1,NCK1,SHC1,CKB,FUBP3,SF3B6,HRAS,CWC15,SNX18,TAGLN2,HNRNPL,CD2AP,TP53,ZC3H14,CRKL,GRAP2,ZNF326,EZH2,PACSIN3,SAP18,HSPE1,KPNA2 |
| 1.341e-03 | -6.61 | H2BC4 (H2B clustered histone 4) | protein interactions | 8347 | 54 | 26 | 19454 | 5460 |
AP2M1,EIF4A3,PARP2,VIRMA,TMPO,TRIM29,HPF1,AR,BTF3,CUL3,MAGOH,HNRNPD,PSMD10,PSMD14,NME2,BCL10,MAP1B,BAP1,MEPCE,MEF2A,UBE2A,VDAC1,H2AX,DLG3,HEXIM1,CHMP4C |
| 1.341e-03 | -6.61 | IRF8 (interferon regulatory factor 8) | protein interactions | 3394 | 54 | 26 | 19454 | 5460 |
IRF8,CDK4,COPS4,FLOT1,ZNF609,HSPE1,TRIM21,SQSTM1,BCL9,IRF6,CBL,TRAF6,MYO6,COPS5,DNTTIP1,IRF1,NFKB1,TLE1,ZBTB17,TOP1,MYBL2,COPS2,IRF2,ETV6,TFE3,VPS72 |
| 1.341e-03 | -6.61 | EXO1 (exonuclease 1) | protein interactions | 9156 | 54 | 26 | 19454 | 5460 |
MYEF2,COMT,NBN,BAP1,CCNF,UBE2I,PCNA,TOP1,MLH3,MSH6,FAH,SSRP1,EGLN3,CCNB1,SFN,CD14,WDR83,CCNA2,YWHAG,YWHAH,YWHAZ,BRCA1,CDK1,RBBP8,YWHAB,ZNF175 |
| 1.341e-03 | -6.61 | NDFIP2 (Nedd4 family interacting protein 2) | protein interactions | 54602 | 54 | 26 | 19454 | 5460 |
DDAH1,TMEM231,IL2RG,CDC42,HCST,WWP1,IL20RB,PTGFR,TSPAN3,FAM8A1,LRP10,RHOU,FAM168A,RABAC1,SAR1B,WWP2,RHOG,AQP2,LMBR1L,PTEN,SLC11A2,NRSN1,NDFIP1,SRC,SMURF1,UQCRH |
| 1.341e-03 | -6.61 | LRRC4C (leucine rich repeat containing 4C) | protein interactions | 57689 | 54 | 26 | 19454 | 5460 |
DOLK,LRRC4,CLEC1A,GJB2,VEZT,SERTM1,ESR2,NOP9,TWSG1,DNAJB9,NOB1,LRRC4B,STX5,UBE2S,NCOA5,DRAM1,CREB3L4,CNPY3,PLP2,AGTRAP,PGAP2,LEPROTL1,EMP3,VLDLR,DVL2,FSTL1 |
| 1.345e-03 | -6.61 | vesicle localization | biological process | GO:0051648 | 185 | 74 | 18204 | 5365 |
PREB,SYNDIG1,TRIM46,SNAP29,TRAPPC2L,TMED9,SNAP91,PIK3CG,SNAP25,TRAPPC13,WASL,NDE1,VPS33A,RAB11B,CDK5,CTNNB1,KIF3B,CEP19,YKT6,RAB11A,PAFAH1B1,DYNC1I1,ARFGAP3,KLHL12,BLOC1S2,BBS5,PPFIA2,NLGN1,TRAPPC3,EXOC5,AP3S2,CCDC186,EXOC8,SYT4,PICALM,BLOC1S5,PSEN1,RAB3A,TRAPPC1,KIF1C,SNAP23,DNM2,CUL3,EXOC3,EXOC1,TRAPPC10,TRAPPC4,FAM91A1,SNAPIN,TESK1,BLOC1S3,CTBP1,MREG,TRAPPC6A,FBXW11,RAB1A,COPS5,SYN3,WDR11,RAB27A,AP1AR,TRAK2,TFG,STXBP1,TSG101,STARD3NL,CDR2L,TRAPPC6B,SYBU,EXOC2,ARL6,SAR1B,ACTN4,MKKS |
| 1.349e-03 | -6.61 | ubiquitin binding | molecular function | GO:0043130 | 104 | 46 | 18094 | 5411 |
DNAAF10,USP16,DNAJB2,VPS28,RNF8,FBXW7,USP13,HSPB1,CXCR4,HDAC6,KLF1,UBE2N,BIRC2,RBCK1,UBE2A,TOM1L1,TSG101,TRIM32,CKS1B,FAF2,USP5,TOM1L2,UBAP1,PLAA,UBXN2B,UBXN10,UCHL3,BUB3,TAB2,MDM2,SMAD3,DHX16,FBXO7,ZFAND2B,TP53INP2,OTULINL,NSFL1C,CKS2,RAD23B,TNFAIP3,FAF1,TOLLIP,NUP62,SQSTM1,HGS,TOM1 |
| 1.355e-03 | -6.60 | intracellular monoatomic ion homeostasis | biological process | GO:0006873 | 437 | 158 | 18204 | 5365 |
TF,MT3,SELENOK,TMEM106B,TFRC,SLC1A1,CYBRD1,RHAG,VDR,ATP5F1B,BAK1,ATP1A1,SLC39A10,IL1A,CHP1,ISCU,ATP6V0E1,BOK,CALR,PPT1,STC1,VAPB,SLC31A1,SLC22A17,SMAD4,SMDT1,DRD3,MT1E,FTHL17,ACO1,S100A8,PRND,HFE,ATP6V1G1,CXCL12,CD40,KCNMA1,CCL23,TMBIM6,COX19,P2RY4,SLC4A8,GPR89A,SRI,LACC1,MT1M,BOLA1,PRKCB,CCR1,CACNB4,HSP90B1,PML,CAV2,TASL,ATP2B4,NPPC,GLRX5,SLC11A2,DISC1,PICALM,ATP1A2,SLC8A1,SOD1,CNR1,MT2A,ATP1B1,VPS54,F2,BOLA2B,CCR2,SLC25A27,CCL19,FIS1,FRRS1,NDFIP1,BOLA3,SLC12A2,DMPK,CFTR,SLC30A7,TMEM203,PLN,RGN,GRIA1,SLC39A7,FTH1,BAX,MYC,ATP1B3,RHCG,LAMP2,NEO1,ARF1,SLC39A13,RMDN3,CLIC4,UBE3A,CACNB2,STOML2,ATP6V0B,CCL5,TM9SF4,ATF4,TMEM165,RNASEK,FASLG,SLC1A3,SLC4A10,CYB561,PRNP,CCL11,MT1X,GRM1,COX11,CCL8,SLC25A23,ATP6V1D,CNNM4,ADORA1,CA2,HTR2A,TRPC1,ATP6AP2,P2RY1,KCNJ2,VPS33A,CCL3,KCTD17,HEXB,CAV3,IREB2,CHRNA7,SLC41A1,FKBP1B,TMEM199,SNAPIN,TPT1,B2M,EDNRA,MAIP1,MT1A,CAV1,FTL,ATP6V1A,ATP2C1,CCDC22,FATE1,PSEN1,SV2B,FXN,ATP1A3,SLC39A9,STIM1,AQP11,SLC30A5,CCL1,NPTN,CCDC47 |
| 1.363e-03 | -6.60 | EXOSC6 (exosome component 6) | protein interactions | 118460 | 116 | 48 | 19454 | 5460 |
RNF113A,PSMA3,C1D,EXOSC4,SOD1,LSM8,BCL6,FBXW7,STAU1,CFTR,CDK7,PALS2,PELO,PSMA6,CCNF,ESR2,TUFM,CHPF,CUL3,MYC,UBE2H,RIT1,RBM7,EXOSC1,BICD2,FAS,MRPS18B,MRPL22,DNAJC30,PSMA2,PSMA1,PSMA5,EXOSC8,SOX2,TOP3B,MOB3C,EXOSC3,EZH2,PSMB1,EIF4E2,MDM2,FZR1,DIS3L,DDRGK1,WWP2,IFI16,MPHOSPH6,SNRNP70 |
| 1.363e-03 | -6.60 | ZNF629 (zinc finger protein 629) | protein interactions | 23361 | 116 | 48 | 19454 | 5460 |
APOBEC3C,RPLP0,FGF17,PGRMC1,NOTCH2,FGF13,RPL4,STAU1,LDOC1,COIL,NUP50,YWHAZ,RC3H2,CCHCR1,SFN,CUL3,ZNF668,PPP1CC,RPL13A,RPL19,VIRMA,RPS3,EIF4A3,ZNF330,ZMYM2,FGFBP1,CBX3,IPO8,RPSA,SPG21,RPL28,GTF3C3,SRSF4,RPL17,RPL3,DDX23,SNRNP70,YWHAB,YWHAG,YWHAH,DDRGK1,GAS8,RPS10,RPS16,SURF6,CDR2L,PRR3,LDLR |
| 1.366e-03 | -6.60 | Platinum drug resistance | KEGG pathways | hsa01524 | 73 | 38 | 7161 | 2463 |
GSTP1,AKT2,FAS,PMAIP1,BAK1,GSTM5,AKT3,CDKN1A,PIK3R3,GSTO1,GSTM4,BAD,PIK3CA,SLC31A1,GSTA4,BAX,ABCC2,GSTO2,PIK3R1,GSTM3,MGST2,AKT1,GSTA2,BRCA1,PIK3R2,TP53,GSTM2,GSTT2B,GSTA1,TOP2B,MSH6,BIRC5,FASLG,BCL2L1,GSTT1,BIRC2,MGST3,MDM2 |
| 1.366e-03 | -6.60 | Platinum drug resistance | KEGG pathways | ko01524 | 73 | 38 | 7161 | 2463 |
MSH6,GSTM2,GSTA1,TOP2B,GSTT2B,FASLG,MGST3,BIRC2,GSTT1,MDM2,BCL2L1,BIRC5,PIK3R1,GSTM3,MGST2,ABCC2,GSTO2,PIK3R2,TP53,BRCA1,AKT1,GSTA2,GSTO1,GSTM4,PIK3R3,BAX,BAD,GSTA4,SLC31A1,PIK3CA,AKT2,GSTP1,CDKN1A,AKT3,GSTM5,FAS,PMAIP1,BAK1 |
| 1.368e-03 | -6.59 | GPVI-mediated activation cascade | REACTOME pathways | R-HSA-114604 | 54 | 28 | 10285 | 3229 |
LCP2,IL3,SYK,PTPN11,MPIG6B,RAC2,IL2RA,SHC1,AKT3,PIK3CG,AKT1,PIK3CA,IL2,AKT2,IL5,FCER1G,RHOB,RHOG,CDC42,VAV2,JAK1,CSF2,PIK3R3,PIK3R1,IL2RB,JAK2,PIK3R2,IL2RG |
| 1.371e-03 | -6.59 | human chr14q11.2 | chromosome location | human chr14q11.2 | 129 | 44 | 26134 | 5823 |
MIR208B,RNASE9,PSMB5,PARP2,PSMB11,DHRS4,DHRS4L1,OSGEP,OR10G3,MRPL52,OR4K1,SLC7A8,OR4Q3,ABHD4,PNP,DAD1,OR4K13,APEX1,OR4M1,OR10G2,CEBPE,THTPA,TOX4,OR4K17,RBM23,LRP10,AP1G2,OR4N2,RNASE6,OR4N5,HNRNPC,JPH4,NGDN,EDDM3B,RNASE4,SLC22A17,MMP14,TPPP2,RNASE1,MIR208A,OR4K2,OR4E2,PIP4P1,PRMT5 |
| 1.373e-03 | -6.59 | V_SNARE_CC | interpro domains | IPR042855 | 12 | 9 | 18521 | 5414 |
VAMP7,VAMP1,VAMP5,VAMP8,YKT6,VAMP2,SEC22B,STXBP6,VAMP3 |
| 1.374e-03 | -6.59 | SRI (sorcin) | protein interactions | 6717 | 76 | 34 | 19454 | 5460 |
FXN,SMAD2,BRCA1,ISCA2,MYC,SRPK2,EGLN3,TXNDC12,ANAPC2,GATD3,ENO1,ALG2,CCNF,HAUS2,MSRB3,ANXA7,SIGMAR1,GRIK1,PIR,MSX2,GLRX5,PRR13,RAF1,MPST,GCA,TOLLIP,RUVBL1,SRI,SSNA1,GUK1,G3BP1,HINT1,PSEN2,SOD1 |
| 1.374e-03 | -6.59 | LEPROTL1 (leptin receptor overlapping transcript like 1) | protein interactions | 23484 | 76 | 34 | 19454 | 5460 |
FCER1G,TMEM42,TMEM11,REEP6,ZDHHC15,MFSD14B,FMO1,PDZK1IP1,SCN3B,TMEM19,SLC25A46,ORMDL3,REEP4,TMEM237,TMEM248,ELOVL4,SSMEM1,PLP1,SYNDIG1,SMCO4,LMNA,SDCBP,TMEM14B,STX12,EHHADH,PAQR8,SPG21,DDX39A,RNF5,SLC7A1,TMEM50A,LEPROTL1,TMEM50B,TMX2 |
| 1.375e-03 | -6.59 | response to dsRNA | biological process | GO:0043331 | 57 | 28 | 18204 | 5365 |
PELI1,IFNA2,FLOT1,HCFC2,IFNA13,IRF3,PQBP1,RALB,DHX9,IFNK,IFIH1,GRIA1,PDE12,CGAS,IFNA10,PMAIP1,NFKB1,KCNJ8,TLR3,MAVS,MUL1,DDX1,NFKBIA,RFTN2,RIGI,TICAM1,CAV1,IFNB1 |
| 1.377e-03 | -6.59 | PPP2CA (protein phosphatase 2 catalytic subunit alpha) | protein interactions | 5515 | 458 | 158 | 19454 | 5460 |
IGBP1,PPFIA3,TRAF3IP3,PPP2CB,EGLN3,SLMAP,CCT7,TRIM35,TCP1,PPFIBP1,PSMD3,PPP2R5A,PDCD10,MRPS26,IKBKB,SKIC8,PPM1B,AKT2,CTTNBP2,CDKN2C,CCT8,PABPC1,PFDN1,AHCYL1,SMCO3,KRAS,PPP2R1A,MSX2,EEF2,RAF1,VDR,MAX,SUPT5H,POLR2D,POLR2C,PIR,PPFIA2,EXOSC3,CHMP4C,INTS10,FAM43A,BAD,VPS72,CBX5,POLR2B,NCKAP1,TNPO3,JAK2,OTUD6A,PSMD1,ISCA2,TTC33,BAG3,MYC,GRB10,KLHDC8A,CUL3,COP1,CCT2,BRCA1,RHOB,NMRAL1,HDAC5,HSPA8,NUBP2,EP300,STK26,DUSP9,SERTAD2,STX7,TNFSF10,PPP2R2C,PPP2R3A,PTN,ATP6V1G2,ETF1,SYK,LACC1,CSNK1A1,PIH1D1,FOXS1,IER2,LCMT1,CDK6,RCHY1,CAV1,BMPR1B,ISYNA1,ID1,ATP6V1D,BCL10,NME2,TIAM1,KLHL15,NOSIP,TFPT,SIKE1,PSME1,DUSP19,MDC1,CAMK2G,SERTAD1,MAP2K3,EEF1A1,CCT5,FAM13B,TP53,VAC14,PPP4C,PPME1,TBC1D4,DMAP1,RP9,CAMK1,GSK3A,MOB4,CSNK2B,PPP2R5E,PTEN,INTS12,TBCCD1,SMURF1,CTTNBP2NL,CDC20,DUSP10,COPE,MAP3K3,STAT5A,PYGM,RALA,DAPK1,PPAT,ADRM1,AR,NPTX1,FGFR1OP2,AKT1,CDC16,AKT3,GABRB3,ANAPC4,PTTG1,CSGALNACT1,UBE2H,NIF3L1,STK24,RNF113A,BAP1,SOD1,RPA3,IRF3,WNT7A,GREM2,CFTR,WSB1,FCAR,ACACA,RPA2 |
| 1.377e-03 | -6.59 | Hepatitis C | KEGG pathways | ko05160 | 131 | 62 | 7161 | 2463 |
IRF7,CLDN22,IRF1,PIK3R3,CLDN3,RNASEL,IFNA13,CLDN11,BAD,SOS2,TNF,PIK3CA,PPP2R2C,STAT1,AKT2,RIGI,CDKN1A,TBK1,EIF2S1,TICAM1,CLDN1,IKBKB,MAPK10,TRAF2,PPARA,IFNAR1,PIK3R1,IRF9,SOCS3,KRAS,OAS1,PIK3R2,AKT1,CLDN9,LDLR,PPP2R1A,CD81,CLDN24,CLDN6,STAT2,TRAF6,IFNB1,AKT3,NFKB1,IFNA10,CLDN14,IRF3,NFKBIA,HRAS,EIF2AK2,JAK1,IFNA2,CLDN8,PIAS1,CXCL8,RAF1,PPP2CB,TLR3,MAVS,CLDN4,EIF3E,TP53 |
| 1.377e-03 | -6.59 | Hepatitis C | KEGG pathways | hsa05160 | 131 | 62 | 7161 | 2463 |
CD81,PPP2R1A,LDLR,AKT3,IFNB1,IFNA10,NFKB1,CLDN24,TRAF6,STAT2,CLDN6,PIAS1,CLDN8,JAK1,IFNA2,PPP2CB,RAF1,CXCL8,NFKBIA,IRF3,CLDN14,EIF2AK2,HRAS,EIF3E,TP53,CLDN4,TLR3,MAVS,CLDN11,IFNA13,PIK3CA,SOS2,BAD,TNF,IRF1,CLDN22,IRF7,RNASEL,CLDN3,PIK3R3,CDKN1A,TBK1,RIGI,TICAM1,EIF2S1,PPP2R2C,AKT2,STAT1,TRAF2,PPARA,MAPK10,IKBKB,IFNAR1,CLDN1,PIK3R2,CLDN9,AKT1,SOCS3,IRF9,PIK3R1,OAS1,KRAS |
| 1.378e-03 | -6.59 | TANK (TRAF family member associated NFKB activator) | protein interactions | 10010 | 209 | 79 | 19454 | 5460 |
GSK3A,UBASH3B,TRMT6,INPP5K,EIF3K,OGN,ESR2,TRAF1,ATP5F1B,ATP5F1A,OTUD7B,NCAPG2,RACGAP1,NAA50,MLF1,TNFAIP3,C9orf72,EPS8,CUL3,AP2A1,PFDN4,BICD2,BIRC2,RAB9A,CD40,RFC4,IRF3,RNF41,NF2,IRF7,NEK2,NTPCR,NUP62,ATG16L1,PAFAH1B1,TANK,OXSR1,CSNK1A1,ADSS2,PPT1,CETN3,SMAD3,SDC4,ANXA4,FUBP3,SUMO2,ZFAND2B,UTP6,TENM3,MAP3K14,ELOC,PFDN5,MARCHF5,FAM20C,HAX1,IKBKB,CNTFR,TRAF6,PICK1,DNAJB4,SCPEP1,ERO1A,ARB2A,TICAM1,RFC3,RNF115,TNF,PELI1,KPNA2,NOC4L,TRIM37,SSNA1,TRAF2,SPRR1B,TBK1,TAB2,JCHAIN,HSPA13,MOXD1 |
| 1.378e-03 | -6.59 | ANKRD17 (ankyrin repeat domain 17) | protein interactions | 26057 | 209 | 79 | 19454 | 5460 |
CEP85,SFN,OST4,MYC,YWHAZ,RC3H2,UBE2H,HOXC4,PSPC1,LMBR1L,CREB1,S100A6,CCNF,TRIM24,RPS20,SYT2,FGFBP1,PRRC2A,ESR2,VIRMA,RPL10,SFRP4,FGF17,CAPN1,CDKN1A,AGO1,LARP4B,CSNK1A1,DYRK2,SIRT7,FOS,RBM23,BAP1,SMG5,RNF113A,YTHDF1,STAU1,FXR2,KDM1A,UTP23,WWP2,RAB5C,TCEANC2,IRF9,CNOT2,YWHAG,CNOT8,CPEB1,YWHAH,FOSL2,YWHAB,EIF4E2,FUBP3,LDLR,MEAF6,FZR1,HNRNPL,RPS16,NUP35,EGLN3,AKAP17A,MDM2,YTHDF2,TNRC6C,ZNF263,TOP3B,RAF1,MAP2K3,SOX2,GARRE1,LSM14A,FGF3,ZC3H7A,G3BP1,CNOT7,RIGI,MSH6,STX11,CNOT6L |
| 1.387e-03 | -6.58 | KLHL22 (kelch like family member 22) | protein interactions | 84861 | 119 | 49 | 19454 | 5460 |
RPP25,DES,BMP1,TRMT6,ZBTB33,HSP90AA1,BRCA1,BICD2,NOA1,GMNN,RBM15B,FMC1,TRIM32,CUL3,ATG4C,EMC1,LCN1,ATPAF2,UBE2M,CCL21,CSNK1A1,NACC2,IPP,MRPL10,OTULINL,GABRA1,CFTR,NOB1,DCUN1D1,LYRM2,SPINT2,IGFBP4,COPS5,ETFRF1,KLHL9,MZB1,SAV1,CTNND1,PAEP,POLDIP3,NEDD8,FAF1,TMEM87A,ADRA1A,KLHL26,NUDCD3,SOX2,METTL15,CSNK1E |
| 1.387e-03 | -6.58 | UXT (ubiquitously expressed prefoldin like chaperone) | protein interactions | 8409 | 119 | 49 | 19454 | 5460 |
RUNX1,FBXO7,PPP1CC,AR,TXNIP,PFDN2,PFDN4,POLR1B,RIT1,PFDN6,POLR3B,MCPH1,POLR2F,POLR3H,SIAH1,UBB,POLR2B,TRAF1,PPP1CB,POLR1D,PAK5,RPRD1B,PIH1D1,SQSTM1,POLR1H,WWP2,MED21,NCK1,ASB7,MED4,RPRD1A,POLR2L,POLR2I,MPP1,MACROD1,E2F4,RPAP2,GLE1,POLR2C,POLR2G,POLR2D,RUVBL2,RPAP3,KRAS,RUVBL1,DNAAF10,TRIM63,PDRG1,PTGES3 |
| 1.387e-03 | -6.58 | FADD (Fas associated via death domain) | protein interactions | 8772 | 119 | 49 | 19454 | 5460 |
SQSTM1,MAVS,IRF3,RNF41,TNFSF10,IRF7,EHD1,TANK,DDIT4L,AKR7A2,CSNK1A1,SDS,CLIP3,SDCBP,UBE2I,MSN,MOB4,STUB1,TAB1,DAPK1,STAT1,NTF4,ZCCHC12,CUL3,TNFAIP3,PEA15,DEDD,SLC7A11,SPOP,FAS,EDA2R,TRIM21,TCEA2,MYD88,HSPD1,FAF1,PRDX4,NUP42,TNF,TRAF2,E2F4,RAP1A,FASLG,BTG1,TPPP,TLR3,GOLGA7B,XPO5,NDNF |
| 1.387e-03 | -6.58 | DDIT3 (DNA damage inducible transcript 3) | protein interactions | 1649 | 119 | 49 | 19454 | 5460 |
NFE2L2,SMARCB1,BATF,SNAPC5,JUN,BACH1,KPNA2,RIGI,PPP1R12A,ZBTB25,ATF3,EWSR1,FOSL2,CSNK2A1,CREBL2,HDAC6,PPIB,RTL6,CDK6,CEBPG,PICALM,ACTL6A,ZC3H14,POLR1D,MAFG,NFIL3,GABBR1,MCMBP,SS18,HSPA5,TNFSF12,SMARCD3,ATPAF2,FOS,HDAC5,DDIT3,EP300,SPOP,CREBBP,COPS7A,LMO2,CREB3,ATF4,F2,CUL3,SMARCE1,CEBPE,JUNB,RPS3 |
| 1.392e-03 | -6.58 | negative regulation of nucleobase-containing compound metabolic process | biological process | GO:0045934 | 1511 | 497 | 18204 | 5365 |
FOXC2,H1-5,CGGBP1,LDB1,H1-6,TFDP2,ZHX3,OGG1,CITED1,RB1,DAP,CGAS,FBXW11,ZBTB45,SPINDOC,NAB1,PHF12,EID2,SDR16C5,APOBEC3B,CDKN1A,MDFI,NDN,SUPT5H,RIOX2,TENT5C,PSMD10,ZNF304,PKIA,FBP1,GABPA,HINFP,KDM2A,CDK5,HEXIM2,PFDN5,BCL6,HMG20A,CXXC5,DFFA,HMGB1,RPS3,TRIM6,ING1,PHB1,FOXP4,H1-1,TRAF2,CBX5,MSX1,TAGLN3,NKX6-2,STN1,RBPJ,YAF2,XCL1,NAB2,FERD3L,BRMS1L,SRSF2,LBH,RBBP7,TNF,ADIPOQ,HMGA1,APOBEC3H,RPL23,PPARG,RBM15B,MIDEAS,SUFU,SLA2,SUV39H1,IMPACT,DCP2,CDKN1B,BTG2,ZBTB6,TSPO,EZH2,EZH1,ESR2,RPS26,CNOT7,ZBTB14,EGR1,ZNF668,EPO,NR4A2,ZNF692,TRIM27,DDIT3,NONO,DNAJC2,CDK6,POLE3,TGIF2LX,PAX9,KLF4,HSPA8,SIX5,SAP18,HELT,PCGF2,NKAP,ATXN1L,FGFR1,UBE2D3,PCGF6,DDX5,VPS72,MITF,ZNF451,MAEL,TENT5D,TP53,MDM2,TAF7,SDCBP,DLG1,IGBP1,IKZF5,MAFG,DICER1,FIS1,SNAI2,NDFIP1,SOX9,CSNK2A1,TADA3,CIRBP,HNRNPA0,SUB1,RGN,TRIM22,DHRS7B,TWIST2,HNRNPC,SUMO1,SHC1,PRMT2,IRF8,HDAC5,CTBP1,SAP30L,ZNF174,TOB2,TRIM29,MACROH2A1,ZBTB26,NR1I2,KDM1A,IRF7,HCFC2,GREM1,SRSF7,ZBTB18,ZNF345,BHLHE40,PROX1,CREBBP,MTDH,MBD3,RNF8,STAT6,THAP7,DDIT4,ZNF177,HSBP1,DYRK1A,DKK1,DHX9,SOX2,IRF2,GCLC,TRIM37,NCK1,MXD1,OTUD7B,ZBTB38,TLE1,PCNA,RING1,RERE,KLHL15,RLIM,NOTCH2,LILRB4,NKRF,MIR146A,PSEN1,TNKS2,ZBTB42,SCML1,S100A11,ZHX1,UBE2I,APOBEC3F,ZGLP1,IL4,BRCA1,SMAD2,MYD88,WWP1,GFI1,ZMYM2,RUNX1,ZMPSTE24,PKIG,BEND6,THAP1,ZCCHC17,RUVBL2,DKK3,ING2,MEF2C,LANCL2,BEND5,CBFB,H1-10,VGLL4,TNKS,ZBTB17,RBFOX2,CAV1,TRIM11,RBBP8,MEPCE,MAGED2,KLF12,CDK5R1,SRSF12,TGIF2,NFIL3,BARX2,HEY2,IRF3,EED,SMAD5,CSF2,OSR2,INPP5K,HNF1B,APOBEC3D,ID1,APOBEC3G,NUPR1,CRYAB,CREB1,MAGEH1,FLCN,SFRP1,IER3,MYC,HCRT,DLX1,WWP2,HNRNPA1,MOSPD1,RPS14,RORB,VIP,PLAGL1,ZBTB39,XRCC5,PIAS1,ZBTB25,TRAF6,GADD45A,RPS13,APOBEC3A,C1D,CD38,PABPC1,SNAI3,NFKB1,CIART,PDE2A,PML,POU1F1,RBM42,PSMC5,PSPC1,HCLS1,IRF2BPL,IGF2BP1,NPPC,CCAR2,APOBEC3C,SGF29,HDAC6,NOG,ATF3,MAGEB1,NKX3-1,BOLL,KLF10,TMBIM6,HNRNPL,MACROH2A2,SETD5,NR1I3,RASD1,IRF2BP1,MAGEA4,HNRNPD,DUSP22,SMAD3,SCML2,MAGEB10,NR2F6,NIF3L1,TCEAL7,NBN,CRYM,CTNNBIP1,NIBAN2,TFIP11,IFI16,MYT1L,CIPC,ELK4,SOX14,MAGED4B,FOXP2,YWHAZ,INSM2,BRMS1,IRF1,CUL3,NR0B1,NR2E1,GTF2IRD1,SATB1,SRSF4,CCAR1,VEGFA,DRAP1,MTA2,MECP2,NUDT16,SOX3,DNAJB4,PRMT6,NSMCE3,SQSTM1,HNRNPK,FASLG,LEP,ATF4,HNRNPA2B1,PHB2,ZNF175,EID1,HEXIM1,PPID,SMARCA5,SRC,ELK3,CCDC85B,NRDE2,KLF3,H1-3,PHAX,ETV6,SUPT4H1,MEF2A,HOXB8,PDCD4,IFNG,APEX1,CBX7,DYNLL1,ZBTB5,BIRC5,TENT2,NCOA5,AR,UBE2D1,TRIM24,HNRNPAB,MIR221,TRIM63,MSH6,HIRA,CCND1,PHF21A,PID1,LMO4,CREBZF,SMCHD1,ABCE1,DEDD,GSK3A,CRY1,TIRAP,STAT1,USP3,NR1H2,MAF1,TSG101,PHC1,MCPH1,E4F1,SMAD4,DUSP26,PRMT5,RADX,SIAH2,NOP53,GMNN,EID2B,ELAVL4,ZMYND11,CCND3,MXI1,SHLD1,BACH1,MAX,TXN,VDR,SP2,CTNNB1,RBBP4,SIRT7,OVOL1,CALR,TCF23,MIR675,CNOT2,DR1,EP300,DKC1,SAP30,FABP4,CDC73,IFNA2,SFN,DNAJB6,WDR82,MSX2,NACC2,RPL10,E2F6,ZNF24,SYNCRIP,ZBTB16,HDAC3,KCNIP3,PLCB1,IREB2,POU5F1,TCF21,RMI2,FOXD3,SRSF10,LIG3,CD36,BAP1,FOXS1,WNT10B,TXNIP,ZBTB33,IFI27,PAX6,SIN3A,LYAR,MAD2L2,SLX1A,TENT4A,SMARCE1,PPARA,ZNF263,MTA3,CBX3,DMAP1,FOXP3,ENO1,HMX1,MORC2,JUN,COPS2,SOX21,BAHD1,PAIP1,RFX5,ID4,IL6,USP2,ZBTB2,TRAF3IP2,PCBP4,LDB2,NKX3-2,THRAP3,FOXP1,MAGEC2 |
| 1.392e-03 | -6.58 | PTPRG (protein tyrosine phosphatase receptor type G) | protein interactions | 5793 | 93 | 40 | 19454 | 5460 |
DUSP22,NCSTN,RND2,ISG20,RND3,RHOU,NPB,TMEM185A,DUSP26,KRAS,RPS15,CERS2,PCGF3,NF2,ADD2,NIBAN2,RAB2A,LAMP2,DPP4,LAMP3,DUS4L,LGALS8,RHOB,FYTTD1,MED21,LAMTOR1,DLG4,RAB35,ACBD7,SLC39A10,GJA1,RHOH,LGALS3,FCHO2,ARF6,HNRNPL,CAV1,VIRMA,LMAN1,DIRAS3 |
| 1.392e-03 | -6.58 | IBA57 (iron-sulfur cluster assembly factor IBA57) | protein interactions | 200205 | 93 | 40 | 19454 | 5460 |
TMEM70,RAB3A,DNAJC19,RIT1,UBE2H,CUL3,PMPCA,GRSF1,AUH,TUFM,ISCA2,NONO,AK3,MTPN,PARL,MTG1,COX4I1,TACO1,SSBP1,GATD3,CZIB,PDHA1,RPA2,MINDY3,PIH1D1,MTRES1,GFM2,MRPL11,GTF2E2,METTL15,CARTPT,AURKAIP1,HSCB,IMMP2L,EXD2,HSPD1,COX8A,GFM1,HINT2,NMRAL1 |
| 1.393e-03 | -6.58 | cellular response to bacterial lipopeptide | biological process | GO:0071221 | 10 | 8 | 18204 | 5365 |
TIRAP,TLR10,MIR105-1,TLR2,CD14,TLR6,CD36,TLR1 |
| 1.393e-03 | -6.58 | ESCRT III complex disassembly | biological process | GO:1904903 | 10 | 8 | 18204 | 5365 |
VPS4A,VTA1,CHMP2A,CHMP1B,VPS4B,CHMP2B,CHMP1A,CHMP5 |
| 1.393e-03 | -6.58 | response to bacterial lipopeptide | biological process | GO:0070339 | 10 | 8 | 18204 | 5365 |
TLR6,CD36,TLR1,TLR10,TIRAP,TLR2,CD14,MIR105-1 |
| 1.393e-03 | -6.58 | cellular response to bacterial lipoprotein | biological process | GO:0071220 | 10 | 8 | 18204 | 5365 |
CD36,TLR6,TLR1,TLR10,TIRAP,CD14,TLR2,MIR105-1 |
| 1.393e-03 | -6.58 | ESCRT complex disassembly | biological process | GO:1904896 | 10 | 8 | 18204 | 5365 |
VPS4A,CHMP1B,CHMP1A,CHMP5,VPS4B,VTA1,CHMP2A,CHMP2B |
| 1.394e-03 | -6.58 | E3 ubiquitin ligases ubiquitinate target proteins | REACTOME pathways | R-HSA-8866654 | 42 | 23 | 10285 | 3229 |
H2BC12,UBE2B,UBE2D1,UBB,UBA52,H2BC9,RPS27A,H2BC1,UBE2D3,UBE2L3,RNF20,UBE2A,UBE2N,RNF152,BCL10,RNF181,RNF40,H2BC14,CDC73,H2BC11,RRAGA,SKIC8,H2BC17 |
| 1.394e-03 | -6.58 | protein localization to cell periphery | biological process | GO:1990778 | 238 | 92 | 18204 | 5365 |
NETO2,EHD3,LRP6,TSPAN15,SLMAP,TTC8,VAMP2,PIP5K1A,NHERF1,PSMD10,STXBP1,LGI1,FGF13,RAMP3,RAB31,TMEM88,TSPAN5,LHFPL4,RAB13,NPTX1,DLG1,EXOC5,HYCC2,ARF6,ATP1B1,VAMP3,SCN3B,CACNB3,NSG1,ROCK2,SPTBN1,TNF,ADIPOQ,HYCC1,RAB11A,SLC1A1,RAB29,RAP1A,RILPL2,EPHA2,GOLPH3L,ZDHHC4,ASB3,PLEKHF1,FCHO2,S100A10,TESC,LIN7B,GOLGA7,IKBKB,CAV1,TPBG,SYS1,CAV3,OPTN,PIGW,JUP,KCNIP3,WDR19,RAP2A,SMURF1,F11R,CRB3,EMP2,CACNG3,TNIK,GORASP2,CD81,ARL6IP5,LIN7C,EHD4,VAMP5,DPP10,PREPL,CACNB2,SEC23A,KCNB1,EHD1,ATP1B3,ROCK1,FRMD8,LARGE1,INPP5K,C1QL3,ERRFI1,P2RY1,AKT2,FLOT1,C1QL2,DLG4,SNAP25,NETO1 |
| 1.397e-03 | -6.57 | Downstream signal transduction | REACTOME pathways | R-HSA-186763 | 352 | 137 | 10285 | 3229 |
PSMB6,PSMA2,ADCY2,DLG4,CD28,CSK,BRAP,PSMA4,PSMB11,PSMC5,FGFR1,IL2,PSMB10,PSMA3,PSMB5,ADCY3,CDKN1B,PSMC4,PSMD3,CREB1,PSMB7,JAK2,PIK3R1,CRKL,AHCYL1,PSMB1,PRKACB,PRKCA,UBB,STAT5A,PPP2R1A,PSMD14,PTPN11,NCK1,PSMD7,CD80,FGF17,SPTBN1,AGO1,PPP5C,PDE1B,PSME1,ANGPT1,SHC3,RAP1A,STAT1,AKT2,JAK1,FGF7,PSMD12,PRKCE,CDKN1A,PIK3R3,CSF2,DUSP10,NEFL,GSK3A,BAD,MAP3K11,PSMB9,SPRED2,IL2RA,FGF3,PSME2,PSMD6,HBEGF,SPTAN1,PDE1A,PIP5K1A,PPP2R5E,PEBP1,PSMB3,MET,PAQR3,FGF23,PTEN,PSMA5,MDM2,YWHAB,DUSP6,FGF1,PPP2R5A,IL2RG,PIK3R2,ICOS,FGF22,UBA52,WDR83,RAF1,TNRC6C,RAP1B,MAP2K1,KRAS,MOV10,FGF10,PIK3AP1,FRS3,PSMD10,SRC,DUSP9,PSMB2,PSMD1,PIK3CA,PEA15,PSMA6,AKT1,AKT3,KIT,LAMTOR2,PPP2CB,HRAS,STAT6,GAB1,IL5,PIP4K2C,VWF,IER3,PSMC1,CUL3,FGF16,IL2RB,LAMTOR3,CAMK2G,RPS27A,IL3,PSMD4,PHB1,SPRED1,PSMC3,TP53,CD86,PSMA1,SEM1,DUSP1,RASGRP3,SHC1,PSMB4 |
| 1.398e-03 | -6.57 | response to alkaloid | biological process | GO:0043279 | 100 | 44 | 18204 | 5365 |
BCL2L1,PPP5C,SLC6A4,MYRF,DHX15,MECP2,GAD2,PRKCE,HDAC5,DRD1,CHRNB2,NQO1,GRIA1,GRM2,OPRK1,SELENON,CCNA2,SLC8A1,CNR1,TIAM1,MDM2,SLC6A3,UBE3A,PDCD4,SLC1A1,CRHBP,SLC1A2,IGF1R,TACR3,UQCRC1,OXTR,PPP1R1B,ELAVL4,SLC6A1,TMEM38B,COMT,GSTM2,HTR2A,CDK5,HOMER1,HSP90AA1,OPRM1,DRD3,SLC1A3 |
| 1.403e-03 | -6.57 | negative regulation of intracellular protein transport | biological process | GO:0090317 | 32 | 18 | 18204 | 5365 |
TXN,CD36,ERLEC1,PKIA,SUMO1,UFM1,ADIPOQ,UBE2G2,SVIP,PKIG,RAB23,OS9,SUFU,ANGPT1,UBAC2,CDK5,CHP1,DERL2 |
| 1.403e-03 | -6.57 | follicular_carcinoma | COSMIC cancer mutations | follicular_carcinoma | 61 | 29 | 16828 | 4835 |
PIK3CA,EZH2,SMARCB1,TSHR,GNA11,RB1,CTNNB1,IDH2,PTPN11,AKT1,MAP2K1,STK11,GNAQ,SF3B1,HRAS,PIK3R1,TERT,FGFR1,TPM3,PTEN,TFG,TP53,MET,KIT,FBXW7,JAK2,SMAD4,KRAS,IDH1 |
| 1.403e-03 | -6.57 | thyroid-carcinoma-follicular_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-follicular_carcinoma | 61 | 29 | 16828 | 4835 |
EZH2,SMARCB1,PIK3CA,IDH2,AKT1,PTPN11,TSHR,CTNNB1,GNA11,RB1,SF3B1,MAP2K1,GNAQ,STK11,PIK3R1,HRAS,TPM3,PTEN,TERT,FGFR1,FBXW7,JAK2,TP53,TFG,MET,KIT,SMAD4,IDH1,KRAS |
| 1.404e-03 | -6.57 | RBMS1 (RNA binding motif single stranded interacting protein 1) | protein interactions | 5937 | 203 | 77 | 19454 | 5460 |
MIR16-2,SECISBP2L,SRPRB,G3BP1,CNOT7,RTCB,FHL3,ZC3H11A,ZC3H7A,PABPC1,LSM14A,PQBP1,FAM136A,TFCP2,PPIF,SOX2,YTHDF2,TOP3B,RAF1,MRPS23,PEG10,MIRLET7G,FAM98A,RFX5,PRR3,PHB1,FUBP3,DNM2,SYNCRIP,DDX1,SMAD9,SNRNP70,CPEB1,PPIB,HNRNPA1,XPO1,GRSF1,MOV10,CNOT2,MIR29A,G3BP2,MRPS7,STX7,STAU1,YTHDF1,FXR2,TRA2B,AKAP1,SMG5,LSM12,MIR205,MCRIP2,MIR7-1,LARP4B,RPA2,CCL3,RBMS2,AGO1,LPXN,RBFOX2,PRRC2A,ESR2,SNX3,UBE2I,RPS20,RTRAF,SMAP2,MRPL53,CASC3,H1-1,IGF2BP1,DCAF4,RC3H2,CEP85,SUGP1,MYC,CSK |
| 1.405e-03 | -6.57 | molecular carrier activity | molecular function | GO:0140104 | 96 | 43 | 18094 | 5411 |
NUP42,XPO1,CYGB,HIKESHI,HBM,NUBP2,DPH3,HBA1,IPCEF1,BAG3,KPNA6,HSPA8,MYD88,EMC10,KPNA2,RANBP6,NGB,EMC2,XPO5,URM1,HBE1,TF,MTCH2,KPNA1,CCS,CSE1L,TNPO2,EMC1,ASF1A,FXN,CLU,TNPO3,NDUFAB1,CALR,HBB,EMC4,EMC8,EMC6,TIMM10,RAN,VPS72,EMC9,COX17 |
| 1.406e-03 | -6.57 | MCOLN3 (mucolipin TRP cation channel 3) | protein interactions | 55283 | 65 | 30 | 19454 | 5460 |
TMEM219,DCAKD,ST7,DDX39A,CYB5R1,TMX4,SLC12A2,TMEM59L,GPAA1,BSCL2,SEMA4C,COA1,TMEM177,RDH11,TUSC3,GABRB3,DHRS7,KCNQ5,RETSAT,CSK,KCNJ8,CCR6,DCAF4,BPNT2,SNX14,ITGA6,MCOLN1,SRPK2,PXYLP1,PTP4A3 |
| 1.406e-03 | -6.57 | DESI1 (desumoylating isopeptidase 1) | protein interactions | 27351 | 65 | 30 | 19454 | 5460 |
TMBIM6,XPO1,PSMA4,CDIP1,MOV10,FAS,PSMB1,PSMC5,PSMB5,PSMA6,FGF7,HRAS,UBB,PSMD4,UBA52,PSMB3,PSMC4,PSMC3,PSMB7,ERP29,KLRF1,PSMD12,NT5C3A,CDSN,PSMC1,RPS27A,HNRNPK,PSMA2,PSMA5,PSMA1 |
| 1.406e-03 | -6.57 | SLBP (stem-loop histone mRNA binding protein) | protein interactions | 7884 | 65 | 30 | 19454 | 5460 |
DCAF11,ZNF473,PTGER4,RC3H2,SNRNP70,FEM1B,CSNK2A1,CUL2,GSTM3,MYC,DHX15,CSTF3,SNRNP40,FZR1,GATAD1,CDK6,CCNF,FEM1A,CDK1,LSM10,TULP3,CCNA2,CDK4,SKP1,MEPCE,COIL,FEM1C,USP8,EP300,SF3B1 |
| 1.406e-03 | -6.57 | APOBEC3F (apolipoprotein B mRNA editing enzyme catalytic subunit 3F) | protein interactions | 200316 | 65 | 30 | 19454 | 5460 |
NUP42,DGCR8,SRSF4,RPL31,SRSF7,RNF7,LARP4B,ZNF574,ILF2,RAF1,RBFOX2,PABPC5,RBMS2,APOBEC3D,RPL35,CGAS,LYAR,PAIP1,RPS16,RPL19,VIRMA,PRKRA,PRR3,DCAF4,SNRNP70,H1-1,ELAVL2,RPL7A,HNRNPC,TRA2A |
| 1.406e-03 | -6.57 | CD47 (CD47 molecule) | protein interactions | 961 | 65 | 30 | 19454 | 5460 |
SYNE4,FZD4,RETREG3,RHAG,GNB3,LILRB4,TYROBP,AGPAT1,FAS,TM4SF18,LGALS8,CTNNB1,CDKN3,ITGAV,TSPAN5,RIGI,WASF3,SLC7A14,LPAR1,TMEM167B,BSCL2,VIPR1,LPAR2,TMEM243,EMP3,TMEM185A,TSPAN15,CCR1,GNAQ,TP53 |
| 1.408e-03 | -6.57 | LCK (LCK proto-oncogene, Src family tyrosine kinase) | protein interactions | 3932 | 455 | 157 | 19454 | 5460 |
GRAP,SHC1,NOS1AP,CD247,DNAJC7,SMAD3,EEF1B2,ITK,AIP,CD4,CDCA3,DSTN,COG1,CD2,LCP2,TMPO,CD28,CD38,CCT5,RPL15,SOCS3,EXOC3,CTLA4,RP9,PIK3CA,DLG1,PALM2AKAP2,CCR5,SNAP23,SEPTIN7,TTC4,WASL,CAMK2G,H2BC14,CTNND1,SOCS2,RPL7A,PTPN11,IL2RB,MAT2A,CSK,ST13,SKAP2,AR,IFNAR1,H2BC9,ATP5F1A,ARHGAP21,EXOC5,CHORDC1,AP2A1,SMAD2,EPHA2,CTNNA1,CCNF,GAB1,STUB1,CSNK2B,YES1,STAT5A,SRC,UQCRQ,SMURF1,FERMT2,SPTBN1,CNP,CDC42,GOLGA5,SLC12A2,PTPN22,JUP,CTDSP1,CDK1,MET,RARS1,HEXIM1,PRKCA,SQSTM1,PIK3R2,STK38,SIT1,HSPA5,FAM174A,UBXN6,PIK3R1,CISH,PPFIBP1,FKBP4,HSPB1,DRG1,CBL,DNM2,WDR6,THY1,SH2D1A,SPTAN1,TCP1,RHOH,TRIM35,TTC9C,OCRL,HSP90AB1,CCT7,PRKCQ,CACYBP,PTS,RAF1,FASLG,CSTF2T,EEF2,NUDCD3,PPID,STIM1,TUBB4B,RPS11,RBM3,CCT8,HSPD1,BAG2,UBE3A,MYO1B,ETFA,KIT,G3BP1,FLOT1,UNC119B,CUL3,PKP4,NIBAN2,BAG3,MAP3K21,BRCA1,MYO6,YWHAZ,CCT2,FAS,HSP90AA1,NFKBIA,RAN,CD79B,RPS9,TUBB,STAT1,MAD2L2,RORB,NOTCH2,SYK,TOMM22,USP6NL,PAK2,PIH1D1,XRCC5,EP300,TTC1,HSPA8,EEF1G,UNC45A |
| 1.408e-03 | -6.57 | CYB5R1 (cytochrome b5 reductase 1) | protein interactions | 51706 | 122 | 50 | 19454 | 5460 |
CYB5B,SLC25A20,CCR1,AQP3,PDHA1,MTCH2,PREB,TOMM6,SLC7A14,HIGD1C,KRAS,GNG5,SFXN1,RAB1A,TMEM30A,MARCHF5,ATP5MG,EMC4,MRPS23,MARCHF4,PHB1,OCIAD2,KCNA2,SLC25A3,CHRNB2,RPA2,TMEM106A,UQCRC1,PRDX3,MPV17,PHB2,HSCB,SLC31A1,EMC1,SLC7A1,AKAP1,HADHA,TTC1,DERL1,TSPAN15,ATP5MK,RPA3,ATP5F1A,ESR2,ACTB,ATP5F1B,SGTA,CYB5R3,VDAC2,UQCRC2 |
| 1.411e-03 | -6.56 | Epstein-Barr virus infection | KEGG pathways | hsa05169 | 199 | 89 | 7161 | 2463 |
ICAM1,PSMD3,PRKACB,PSMC4,NFKBIA,EIF2AK2,TP53,YWHAZ,IFNG,POLR2F,SYK,CDKN1B,PSMD1,PSMD12,CSNK2B,CD40,IL10,MYC,CSNK2A1,TRAF6,FGR,IKBKB,MDM2,CREBBP,MAPK10,PSMD7,MAP2K3,NFKBIB,PSMC1,TRAF1,POLR2L,PIK3R2,AKT1,GTF2E2,ENTPD3,RAN,HSPB1,SEM1,PIK3R3,YWHAB,MAP2K6,TBK1,PSMC5,CD38,JAK1,MAP3K14,RB1,GTF2E1,RBPJ,IRF3,POLR1D,EP300,XPO1,PSMD14,CD58,POLR2C,POLR2G,HDAC5,POLR3GL,TAB1,YWHAH,AKT3,POLR3B,TNFAIP3,GTF2B,NFKB1,POLR2I,ADRM1,PSMD4,TRAF2,CCNA2,POLR3H,AKAP8L,PSMD6,POLR2D,PIK3R1,PIK3CA,HSPA8,HSPB2,YWHAG,TAB2,CDK1,RIGI,CDKN1A,POLR2B,POLR3F,PSMC3,AKT2,JUN |
| 1.411e-03 | -6.56 | Epstein-Barr virus infection | KEGG pathways | ko05169 | 199 | 89 | 7161 | 2463 |
TBK1,PSMC5,CD38,RAN,HSPB1,SEM1,MAP2K6,YWHAB,PIK3R3,POLR2L,PIK3R2,GTF2E2,AKT1,ENTPD3,CREBBP,MDM2,MAPK10,IKBKB,PSMD7,NFKBIB,PSMC1,TRAF1,MAP2K3,MYC,CSNK2A1,FGR,TRAF6,CDKN1B,PSMD12,PSMD1,CD40,IL10,CSNK2B,TP53,YWHAZ,POLR2F,IFNG,SYK,ICAM1,PSMD3,PRKACB,NFKBIA,PSMC4,EIF2AK2,CDKN1A,RIGI,CDK1,PSMC3,POLR3F,POLR2B,AKT2,JUN,PIK3CA,HSPA8,YWHAG,TAB2,HSPB2,AKAP8L,PSMD6,POLR2D,PIK3R1,TRAF2,CCNA2,POLR3H,AKT3,GTF2B,TNFAIP3,NFKB1,POLR3B,PSMD4,POLR2I,ADRM1,POLR3GL,TAB1,YWHAH,PSMD14,XPO1,POLR2C,CD58,POLR2G,HDAC5,JAK1,MAP3K14,RB1,GTF2E1,RBPJ,IRF3,POLR1D,EP300 |
| 1.416e-03 | -6.56 | Interferon alpha/beta signaling | REACTOME pathways | R-HSA-909733 | 69 | 34 | 10285 | 3229 |
OAS1,IFI35,SAMHD1,RNASEL,IFNA13,ISG20,MX2,SOCS3,IRF3,BST2,IFNA10,JAK1,ISG15,IRF2,IRF6,IFIT2,IRF9,IFNA2,IRF7,IRF8,IFI6,STAT1,IRF1,IFI27,MX1,IFNB1,IFNAR1,STAT2,IRF4,PTPN11,XAF1,PTPN1,RSAD2,EGR1 |
| 1.425e-03 | -6.55 | polyamine biosynthetic process | biological process | GO:0006596 | 14 | 10 | 18204 | 5365 |
OAZ1,SRM,AZIN2,SAT2,OAZ3,OAZ2,AZIN1,PAOX,SAT1,ODC1 |
| 1.425e-03 | -6.55 | relaxation of cardiac muscle | biological process | GO:0055119 | 14 | 10 | 18204 | 5365 |
ATP1A1,PIK3CA,PLN,ATP1B1,CHGA,KCNJ2,RGS2,SLC8A1,GSTM2,ATP1A2 |
| 1.425e-03 | -6.55 | outer mitochondrial membrane organization | biological process | GO:0007008 | 14 | 10 | 18204 | 5365 |
MTCH2,TOMM70,TOMM20,MTX2,TOMM40,TOMM7,TOMM6,HSP90AA1,TOMM22,SAMM50 |
| 1.425e-03 | -6.55 | macromolecule depalmitoylation | biological process | GO:0098734 | 14 | 10 | 18204 | 5365 |
DESI1,ABHD13,LYPLA2,ABHD17A,ABHD10,ABHD12,LYPLAL1,PPT1,LYPLA1,DESI2 |
| 1.425e-03 | -6.55 | protein insertion into mitochondrial outer membrane | biological process | GO:0045040 | 14 | 10 | 18204 | 5365 |
TOMM20,TOMM70,TOMM40,MTX2,TOMM6,TOMM7,HSP90AA1,SAMM50,TOMM22,MTCH2 |
| 1.425e-03 | -6.55 | cellular response to oxidised low-density lipoprotein particle stimulus | biological process | GO:0140052 | 14 | 10 | 18204 | 5365 |
TLR4,MIR146A,TXNIP,MYD88,AKT1,ADTRP,TLR6,CD36,MIR20A,TICAM1 |
| 1.425e-03 | -6.55 | fatty acid elongation | biological process | GO:0030497 | 14 | 10 | 18204 | 5365 |
ELOVL3,ELOVL4,HACD4,ELOVL6,TECR,HACD2,ELOVL7,HACD1,HACD3,ELOVL1 |
| 1.425e-03 | -6.55 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological process | GO:1901029 | 14 | 10 | 18204 | 5365 |
ACAA2,SLC25A5,SLC35F6,SLC25A31,BOK,TMEM14A,SLC25A4,GCLC,BAK1,IER3 |
| 1.425e-03 | -6.55 | positive regulation of MHC class II biosynthetic process | biological process | GO:0045348 | 14 | 10 | 18204 | 5365 |
XBP1,RFX5,JAK2,RFXANK,RFXAP,TMEM106A,IFNG,IL4,TLR4,IL10 |
| 1.428e-03 | -6.55 | ATAD3B (ATPase family AAA domain containing 3B) | protein interactions | 83858 | 197 | 75 | 19454 | 5460 |
FTSJ3,HTRA2,SMAD2,CUL3,PMPCA,MYC,MTG2,TUFM,BTF3,MATR3,DYRK1A,ESR2,PARL,SRPK2,CCDC90B,LMBR1L,BAD,CCNF,DKK3,EIF2S2,SSR1,RPA2,CYC1,BET1,MTF1,TIMM29,CDC42,GABRA1,PHB2,STAU1,SLC25A51,NF2,UFL1,EXD2,DVL2,RPA3,PRKD3,SQSTM1,MED13L,SHC1,MED21,DYRK1B,MAPK4,NFKB1,DPP4,DDRGK1,EIF2B5,HNRNPL,SPPL3,FZR1,COX14,ZBTB2,PLGRKT,SLC25A12,EGLN3,COX4I1,AIFM1,PDHA1,PNMA2,TFCP2,RPN1,PPP4C,MTCH2,LGR4,PPP2R1A,APOO,SOX2,DNAJC30,PAGR1,MEPCE,FBXO25,SFXN1,CD83,S100B,HSPD1 |
| 1.428e-03 | -6.55 | PDPK1 (3-phosphoinositide dependent protein kinase 1) | protein interactions | 5170 | 197 | 75 | 19454 | 5460 |
CSK,AKT1,AKT3,SEC13,SFN,CUL3,PRPF31,PCCB,SPOP,YWHAZ,NRP1,HSP90AA1,PEA15,ILK,UQCRC2,DDIT4,PHAX,UBE2I,TCAP,PRKCE,IDE,SRC,GNB1,VIRMA,TANK,GPC4,UQCRC1,FAXC,SDC2,JUP,PRSS23,CDAN1,RPA3,PNO1,PRKCB,HSPA8,SQSTM1,HADHA,SLC31A1,GTF2I,GPC1,GRPEL1,CDSN,ZDHHC17,POLDIP2,HSPA5,XPO1,YWHAG,YWHAH,UBFD1,YWHAB,OSBPL8,WDCP,SDC4,MAP1LC3A,FAM199X,SNX18,PRKCQ,CSNK1E,SLC29A1,SOCS3,PLS3,SMARCB1,AKT2,PALM2AKAP2,PSME1,BAG2,DHX9,KRAS,G3BP1,AKAP12,ROCK2,APBB3,IMMP2L,HS2ST1 |
| 1.431e-03 | -6.55 | SNAI2 (snail family transcriptional repressor 2) | protein interactions | 6591 | 41 | 21 | 19454 | 5460 |
RNF8,TRIM23,RNF146,CTBP1,PSMD1,CSNK2A1,TP53,PSMD3,CREBBP,USP5,MDM2,PSMC1,PIAS1,KDM1A,UBE2I,PSMA3,SAT1,PPP2CB,SIN3A,FBXO31,STUB1 |
| 1.431e-03 | -6.55 | ZNF511 (zinc finger protein 511) | protein interactions | 118472 | 41 | 21 | 19454 | 5460 |
LSM6,MED10,LHX2,LSM3,NTAQ1,PPP2R1A,LSM5,RPL35,BOLA2B,CYFIP2,ZNF511,COPE,LSM4,ENKD1,MAD2L2,ATP6V1G1,NCKAP1,MEPCE,SCNM1,GNB3,KLHL15 |
| 1.431e-03 | -6.55 | NDUFA1 (NADH:ubiquinone oxidoreductase subunit A1) | protein interactions | 4694 | 41 | 21 | 19454 | 5460 |
NDUFS3,NDUFS6,RIT1,NDUFA5,NDUFB8,NDUFA12,TOR1AIP2,NDUFA2,NDUFB7,NDUFB6,TOP3B,NDUFB10,NDUFAB1,NDUFV2,DNAJC30,TRIM63,NDUFS2,NDUFS8,NDUFB4,NDUFB5,NDUFC2 |
| 1.440e-03 | -6.54 | establishment of organelle localization | biological process | GO:0051656 | 410 | 149 | 18204 | 5365 |
SNAP23,NEFL,ENKD1,GJA1,BUB3,TRAPPC10,EXOC3,CBL,KIT,EXOC5,BECN1,TRAPPC3,EXOC8,PICALM,DLG1,KIF1C,RAB3A,FEZ1,LAT2,MIS12,NHERF1,TFG,MAD2L1,TSG101,MCPH1,STXBP1,NUP62,ACTN4,ARL6,EXOC2,SYBU,BORCS8,TESK1,FAM91A1,CHGA,FBXW11,CPLX2,TRAPPC6A,UBXN2B,COPS5,RAB27A,SKA3,ABCE1,TUBA1A,WDR11,RB1,SYK,LMNA,WASL,KXD1,RAB11B,NUF2,CDK5,HSBP1,RAB6A,NSFL1C,VPS4B,HDAC6,TRIM46,PREB,TMED9,KLHL12,PDCD10,ARMCX3,XPO1,PPFIA2,CTNNB1,FGF10,MRGPRX2,SPC24,MAP1B,YKT6,RAB11A,RAN,DNM2,HDAC3,CUL3,TERB2,MAPRE1,EXOC1,YWHAZ,CHMP5,UBE2B,DSN1,SYT4,CHMP4C,CCDC186,BORCS5,AP3S2,CCNB1,BLOC1S5,TRAPPC1,BICD2,PSEN1,CHMP2A,AP1AR,TRAK2,CDR2L,STARD3NL,PAX6,PTGDS,SAR1B,TRAPPC6B,NDC80,MKKS,BLOC1S3,SNAPIN,TRAPPC4,RAB1A,MREG,CHMP2B,BORCS7,MGARP,NDE1,PSRC1,TRAPPC13,CHMP1B,ZBED3,SPRY1,SNAP29,LMNB1,PIK3CG,SNAP91,TRAPPC2L,CFL1,SNAP25,RPS15,MAP4,PAFAH1B1,BBS5,ZNF207,BLOC1S2,ARFGAP3,BORCS6,DYNC1I1,SKA2,CDC23,MAP1S,NOP9,NLGN1,KIF3B,SKA1,ARHGAP21,CEP19,CDC42,VPS4A,UBB,CHAMP1,CHMP1A |
| 1.441e-03 | -6.54 | EIF3CL (eukaryotic translation initiation factor 3 subunit C like) | protein interactions | 728689 | 96 | 41 | 19454 | 5460 |
CDC42,H1-5,RPS23,UBE2M,RPS11,METTL14,EMC9,RPS24,RAB5A,RPL23A,MAP1B,BAP1,EIF3E,RPS4X,RPL4,KRAS,UFL1,DDRGK1,EIF3D,CSNK2A1,CD81,HDAC6,CUL3,ENY2,RIT1,BRD3,RPS2,RPS5,ICAM1,RPS26,EIF3G,RPS12,RPS20,METAP2,EIF3K,RPS3,ESR2,DYNC1I2,RPL35,FZR1,OCRL |
| 1.441e-03 | -6.54 | RNF138 (ring finger protein 138) | protein interactions | 51444 | 96 | 41 | 19454 | 5460 |
ARHGAP12,FAXC,EEF1A1,TULP3,CD59,LNX2,TP53,UBE2W,FAM136A,UBE2M,RNF7,CPNE2,ARPC2,PPP1R12A,EIF1AD,RIGI,H3C1,UBE2K,XPO1,COPS5,NTAQ1,CTNNB1,PSMB2,CUL3,TRIM8,TAF9,RBBP8,ADD1,PCBP4,AP2M1,RPS3,NAP1L5,CCNF,TMPO,EGLN3,POLE3,GNAI2,TMOD3,LYAR,RBBP4,SPTAN1 |
| 1.441e-03 | -6.54 | SPIN1 (spindlin 1) | protein interactions | 10927 | 96 | 41 | 19454 | 5460 |
CRBN,RC3H2,MAGOH,HSPB1,UBE2H,STK38L,PRMT6,PPIL4,RIOK2,BAG3,FZR1,HNRNPL,PYGM,YES1,SPINDOC,SMURF1,CGGBP1,VIRMA,CD274,EIF4A3,SCNM1,DDX42,CHMP4C,UBE2M,TOPORS,EIF1AX,UBL4A,RAF1,TP53,E2F4,UFL1,PTN,THRAP3,VDAC1,HMGB1,SAR1B,RIGI,SSRP1,BAP1,SOD1,HSD17B10 |
| 1.441e-03 | -6.54 | PDPR (pyruvate dehydrogenase phosphatase regulatory subunit) | protein interactions | 55066 | 96 | 41 | 19454 | 5460 |
HSPD1,EXD2,HINT2,COX8A,HSCB,HSPE1,FASTKD5,RIGI,IMMP2L,CRYZ,FOXP4,ATP5PB,MRPL11,TP53,SUFU,METTL15,PDHA1,GFM2,MTRES1,SDHB,TACO1,AIFM1,SSBP1,CCDC90B,COX4I1,MTG1,ENO1,GATD3,EGLN3,RMND1,PARL,AUH,MTRF1,MTG2,MOV10,PMPCA,CUL3,PFDN5,TUFM,MRPS26,POU5F1 |
| 1.441e-03 | -6.54 | MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2) | protein interactions | 5871 | 96 | 41 | 19454 | 5460 |
TRAF2,GABARAPL1,GABARAPL2,PIP5K1A,MRPL11,POLR2C,TFB1M,KIN,PYM1,MAP3K11,PRPF4,HNRNPA2B1,RBM3,NHP2,PRDX4,GABARAP,BRIX1,G3BP1,SRSF2,PRPF31,MPG,GRSF1,HSP90AA1,CDKL2,CIRBP,RTRAF,PRKRA,SNRPD2,NAA30,SF3B6,TRMT6,DEFB1,SDHB,RPL32,SRSF1,STK3,SNRPB2,ZNF622,RPP25L,NKAP,SNRPA1 |
| 1.442e-03 | -6.54 | protein transmembrane transporter activity | molecular function | GO:0008320 | 27 | 16 | 18094 | 5411 |
TOMM22,TIMM17A,TOMM20,SEC61G,AZGP1,TOMM40,TOMM40L,TOMM7,TOMM70,BLOC1S3,SEC61A2,SEC63,SEC61A1,TIMM23,MCL1,PEX13 |
| 1.442e-03 | -6.54 | ATPase activator activity | molecular function | GO:0001671 | 27 | 16 | 18094 | 5411 |
DNAJC1,DNAJC7,DNAJB6,ATP1B1,ATP1B3,NKRF,AHSA1,DNAJC19,TOR1AIP2,HSCB,DNAJB2,DNAJC2,DNAJC10,DNAJC24,DNAJB4,GTF2H4 |
| 1.442e-03 | -6.54 | CEBPZ (CCAAT enhancer binding protein zeta) | protein interactions | 10153 | 237 | 88 | 19454 | 5460 |
LRRTM3,VAPB,SYK,STAU1,ZNF692,COIL,DCAF4,ATG3,RIT1,CDKL2,MYC,ZNF668,BTF3,PROX1,THAP7,RPL35,LAMTOR3,SNRNP40,ESR2,RPL19,APEX1,LMBR1L,RPL37A,HDAC11,EZH2,RPL18,E2F4,MAGEB10,RAF1,ZNF263,MAK16,KRAS,RPL28,FGF3,RPL31,UBE3A,RPS24,COX8A,DDX23,IFI16,ATG7,LYAR,RPL8,RXRG,EED,GRM2,RPA2,MACROH2A2,STAT6,RPLP0,NFYB,RPS14,FGF13,CDC42,FBXW7,RPL4,NPM3,UTP23,SIRT7,NLE1,NOG,RPA3,MECP2,UBE2H,RPL7A,PPP1CC,HMOX2,PCBD1,RPL13A,SRPK2,RPL22,ZNF330,EIF2AK2,RPS20,FGFBP1,PRKRA,RBM34,ILF2,TP53,RPL15,RPL17,RPL3,RPS2,FZR1,SURF6,ZBTB2,SRP14,SYNCRIP |
| 1.445e-03 | -6.54 | H2AZ2 (H2A.Z variant histone 2) | protein interactions | 94239 | 128 | 52 | 19454 | 5460 |
CAND1,SRSF1,SRP14,FOLR1,RAC2,AGR2,RHOG,TUBG1,BRD3,WWP2,VRK1,VDAC1,XPNPEP1,PSMA1,G3BP1,NUP107,MEPCE,CCAR1,RUVBL2,EWSR1,PCNA,CHMP4C,EZH2,RHOBTB1,INSIG2,HEXA,MATR3,DLST,OPTN,CCNF,GSK3A,HERC4,XPOT,CUL3,MORF4L1,TM9SF4,MYC,H2BC9,BTF3,PRKACB,FBXO7,RPA3,RPL27,RAB5A,NUBP2,PRKCB,HSP90B1,H2AC7,RPA2,PIH1D1,HEXIM1,TPT1 |
| 1.445e-03 | -6.54 | ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2) | protein interactions | 10564 | 128 | 52 | 19454 | 5460 |
FAM234A,RPA2,RPA3,CD40,RAB9A,NPTN,STX7,CUL3,PRMT6,GPR17,RAB11A,GABRB3,MYC,BRCA1,LAMTOR1,CSGALNACT1,ICAM1,CDC73,CD79B,CSNK2B,RHOJ,PSMD4,MRPL23,VIRMA,ARFGEF1,TOP3B,CLEC2B,MGARP,RAB4A,SIGLECL1,CYB5B,STK16,GABRB2,MADCAM1,LDLRAD4,HNRNPF,FKBP2,DPY30,ANKMY2,DNAJB2,LAMP2,PSMD3,CTNNB1,HSPB8,LAMP3,PDCD1,PSMD7,HAX1,HRAS,RAB35,RAC2,STX6 |
| 1.445e-03 | -6.54 | protein kinase regulator activity | molecular function | GO:0019887 | 235 | 92 | 18094 | 5411 |
MT3,PKIA,PIK3CA,CCND3,HEXIM1,LILRB4,IL6ST,RPLP1,HSP90AB1,CDKN1B,EFNA5,SPRED2,HBEGF,DELE1,CCNB1,CCNI,VEGFA,MNAT1,DNAJC3,DUSP19,PAK2,SFN,NEK9,CCNF,CSNK2B,EPO,CCNY,MACROH2A1,CAV1,AFAP1L2,HTR2A,PKIG,CAMK2N1,YWHAG,SPRED1,CAMK2N2,HYAL2,CDKN2C,CCNH,MOB3C,PDE8A,TESC,STRADB,SOCS3,CCNQ,CD40LG,STAP1,CCND1,CHP1,STK11,ADIPOQ,HSPB1,PRKRA,RGCC,AGAP2,GSKIP,MAP3K12,CNPPD1,RHEB,MAP2K1,PKIB,CDK4,SH3BP5L,CDKN1A,PRKAG1,TOM1L1,CKS1B,CCNA2,PPP1R1B,TAB1,ELP3,YWHAB,CDK5R1,CAB39,CCL5,AKT1,ALKAL1,STK3,NBN,HEXIM2,NCK1,TOPBP1,CKS2,FAF1,CXCL10,TRIB1,CDKN2D,MOB3B,GHRL,RAC2,STK4,GREM1 |
| 1.446e-03 | -6.54 | regulation of receptor recycling | biological process | GO:0001919 | 25 | 15 | 18204 | 5365 |
PSEN1,TBC1D16,RAB29,VAMP3,BVES,OPTN,RAMP3,CHMP5,NSG1,PCSK9,LDLR,GRIA1,AP1AR,LAMTOR1,ACHE |
| 1.446e-03 | -6.54 | negative regulation of glycoprotein biosynthetic process | biological process | GO:0010561 | 25 | 15 | 18204 | 5365 |
ITM2B,MIR106A,MIR455,MIR101-1,MIR298,MIR31,MIR144,AATF,MIR17,MIR20A,ITM2A,HBEGF,ACOT8,MIR153-1,MIR147A |
| 1.447e-03 | -6.54 | negative regulation of lipid localization | biological process | GO:1905953 | 65 | 31 | 18204 | 5365 |
MIR206,MIR301B,AKT1,MIR148A,MIR17,TSPO,AKT2,ITGAV,LEP,MIR146A,PPARA,PTPN11,PPARG,FIS1,ABHD5,MIR130B,MIR144,APOC2,PCSK9,NR1H2,MIR185,TNF,NFKBIA,MIR9-1,OSBPL8,MIR34A,MIR33B,MIR145,IL6,CRY1,NFKB1 |
| 1.447e-03 | -6.54 | glycosaminoglycan biosynthetic process | biological process | GO:0006024 | 65 | 31 | 18204 | 5365 |
IL1B,ANGPT1,CSGALNACT2,PXYLP1,HAS3,EXT1,CHST1,CHST2,CHST11,ST3GAL2,HS3ST3A1,CHST7,UGDH,UST,CHPF2,ST3GAL4,B4GALT4,NDST3,CHST13,CHST9,ABCC5,CHPF,CSGALNACT1,B4GALT7,ST3GAL1,B4GAT1,HS3ST1,NDST1,GLCE,B3GNT2,HEXA |
| 1.447e-03 | -6.54 | regulation of sprouting angiogenesis | biological process | GO:1903670 | 65 | 31 | 18204 | 5365 |
MIR34B,SMAD1,TSPAN18,JMJD8,FGF1,MIR125A,IL10,SYNJ2BP,MIR1-1,MIR126,VEGFA,GLUL,MIR34A,MIR495,MIR377,FGF16,MIR20A,GHRL,MIR17,MIR34C,RHOJ,MIR30E,JAK1,MIR1224,FUT1,MIR31,MIR375,KLF4,MIR221,MIR30B,MIR23A |
| 1.447e-03 | -6.54 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090101 | 200 | 79 | 18204 | 5365 |
MIR424,ING2,GREM2,DKK3,MIR195,LEMD3,EID2,MIR210,SAP30L,MIRLET7G,MIR204,SOSTDC1,CAV2,SIN3A,FKBP1A,UBE2D1,MIR497,MIR146A,CHST11,PPARG,MIR130A,MIRLET7B,BRMS1,MIR342,MIR373,MIR106A,ACVR1,LDLRAD4,MIR100,MIR20A,MIR214,SMURF1,MIR17,HSPA5,HTRA1,SPRED2,MIR490,MIR9-1,UBE2D3,ING1,MIR142,ZNF451,CCN3,TNFAIP6,RBBP4,SOST,SFRP1,MIR302B,MIR145,BRMS1L,MIR101-1,DLX1,TP53,TWSG1,SAP30,SPRED1,RBBP7,PEG10,MIR140,PPARA,MIR361,MIR23A,GREM1,CHRDL1,CER1,SPRY1,EMILIN1,MIR98,USP15,NOG,DKK1,FAM89B,CTDSPL2,MIR885,TGFB3,MIR205,STUB1,PBLD,MIR26B |
| 1.450e-03 | -6.54 | ribose phosphate metabolic process | biological process | GO:0019693 | 407 | 148 | 18204 | 5365 |
ABHD14B,PGAM1,EPHA2,OLA1,NDUFA1,LDHA,PPAT,PDE8A,SULT1A3,FKRP,PFKFB2,ATP5MK,PDHB,NME2,NDUFA5,GTPBP1,UCKL1,PPT1,ATP5MG,NT5C2,RPIA,PDE1A,UQCC3,UCP2,PRPS1,NUDT2,ATP5PD,GPAM,ATP5F1B,NPR2,G6PD,ENTPD4,TECR,ATP5PF,TPST1,PDHA1,BPGM,ACAT1,NDUFA2,ATP1A2,RPE,MVD,ACOT8,UMPS,DLG1,PTHLH,SDHB,ATP1B1,UCK1,ELOVL6,PDE2A,NUDT9,NPPC,CLPX,DCK,NUDT3,BAD,ELOVL1,ACACA,NDUFB5,ATP5MC1,ATP5F1D,ADCY2,CACNB4,GUCY1B1,ENO1,HTR2A,ACSS2,DLAT,HSPA8,NDUFS8,PNP,ATP5F1A,NDUFB10,NME1,NDUFAB1,GLYAT,PDE4B,ENO2,UPRT,MPP1,UCK2,COX11,NDUFA12,PDE7A,NDUFB7,ATP5MC3,SULT1B1,MMUT,NUDT18,HACD2,GMPS,ADK,GNAI3,SUCLG2,NDUFS2,ELOVL3,CASK,RAB23,ATP5PB,FITM2,NUDT4,STOML2,DNAJC30,ACSL4,DLST,SLC25A1,NDUFB6,PGM1,IER3,NDUFV2,PRPSAP1,NDUFS6,OGDHL,MFN1,NDUFC2,GUK1,RAN,PDE9A,NUDT5,SDHC,PAPSS2,NDUFB8,NUDT7,ELOVL4,ATP5PO,PGK1,LIPA,AK5,GAPDH,DCAKD,HACD1,ELOVL7,AK2,ADSS2,ATP6V1A,ADCY3,NDUFB4,HINT1,AK3,ATP5F1E,NDUFS3,ACOT6,FAR2,CMPK1,NUDT19,HMGCS1,NME4 |
| 1.451e-03 | -6.54 | PFKL (phosphofructokinase, liver type) | protein interactions | 5211 | 191 | 73 | 19454 | 5460 |
ABCE1,HAPSTR1,MYD88,HSPD1,PABPC1,HNRNPDL,FOXP4,RIGI,RAD21,EEF1A1,FAF2,SOX2,TUBA1A,EEF2,TOP3B,POLR2C,NUPR1,TAF10,APEH,FURIN,VPS33A,EZH2,PLS3,DISC1,COQ8A,CACYBP,CDK9,CDC5L,HNRNPL,SUMO2,HDAC6,DDRGK1,GAPDH,DPP4,PDIA3,TESK1,DNAJC7,TSNAX,DDX23,HSPA8,RNF113A,RPA3,BAP1,PML,PYGB,COIL,HSPA5,FBXW7,STAU1,EEF1G,PRDX3,CFTR,PGRMC1,CSNK1A1,ADSS2,RPA2,USP39,CCNF,ESR2,VIRMA,MATR3,CTSB,TXN,TUBB,TENT5C,ATP5F1A,ATG101,TNFAIP3,MYC,NRP1,UBE2H,SPOP,BRCA1 |
| 1.452e-03 | -6.54 | SLC7A11 (solute carrier family 7 member 11) | protein interactions | 23657 | 79 | 35 | 19454 | 5460 |
SCN3B,MAPK4,TNFAIP3,RAB2A,EPHA2,PPTC7,RHOB,RHOG,SPOP,RAC2,HRAS,CAV1,MAD2L2,RAMP3,RHOH,RHOJ,ARMC6,ARF6,KLRD1,CDC42,TRAF2,CNPY3,RND2,RND3,KLRC2,TERT,HECTD3,SYVN1,RHOU,HS2ST1,SOCS2,TNFSF8,KRAS,UBE2K,TRIM26 |
| 1.452e-03 | -6.54 | THOC3 (THO complex subunit 3) | protein interactions | 84321 | 79 | 35 | 19454 | 5460 |
UBE2H,RIT1,THOC6,CCT2,SNRNP70,BRCA1,ZCRB1,API5,MYC,CUL3,EGLN3,APEX1,CCT7,ESR2,FBXO22,TCP1,THOC1,PTEN,THOC2,ALYREF,DLG4,UBE2M,NUPR1,PAK2,TULP3,ATG16L1,RAF1,CCT5,ZC3H15,KRAS,UFL1,ZC3H11A,APPBP2,TTC1,DDX39B |
| 1.453e-03 | -6.53 | Anapc16 (anaphase promoting complex subunit 16) | protein interactions | 52717 | 26 | 15 | 19454 | 5460 |
NEK2,ANAPC15,ANAPC13,CDC16,CCNB1,CDC26,ANAPC4,CDC23,CDK1,ANAPC16,ANAPC2,CDC20,CLIC4,RABIF,FZR1 |
| 1.453e-03 | -6.53 | TTC14 (tetratricopeptide repeat domain 14) | protein interactions | 151613 | 26 | 15 | 19454 | 5460 |
IK,DDX23,FRA10AC1,MYC,CCNQ,CCDC85B,ESS2,SNRNP40,NKAP,PRNP,HNRNPL,KRAS,CDC5L,CDK9,SNIP1 |
| 1.453e-03 | -6.53 | CCL28 (C-C motif chemokine ligand 28) | protein interactions | 56477 | 26 | 15 | 19454 | 5460 |
PSMA3,STUB1,CXCL14,CCL17,DYNLT3,DDI1,CXCL10,CCR3,CXCL9,CCL5,CXCL13,CCL11,CXCL12,XCL1,CCL21 |
| 1.453e-03 | -6.53 | SRCIN1 (SRC kinase signaling inhibitor 1) | protein interactions | 80725 | 26 | 15 | 19454 | 5460 |
PRNP,FBXO22,MIF,GPM6A,SNAP25,HNRNPL,ESR2,RIGI,SRC,CTNNA1,SYP,BCAS4,CSK,CTNNB1,FBXO7 |
| 1.453e-03 | -6.53 | orf4b (NS4B protein) | protein interactions | 14254597 | 26 | 15 | 19454 | 5460 |
PSMA6,PSMB5,NUP50,PSMA3,KPNA2,HUWE1,PSMA1,RNASEH1,PSMA5,RPS27A,UBL4A,KPNA6,NUP153,PSMC3,KPNA1 |
| 1.454e-03 | -6.53 | response to gamma radiation | biological process | GO:0010332 | 52 | 26 | 18204 | 5365 |
ZMPSTE24,CBL,HRAS,XRCC5,MIR21,RPL26,POLB,MDM2,CXCL10,BCL2L1,ELK1,GTF2H5,TP53,CDKN1A,KDM1A,PML,EGR1,IL1A,H2AX,BAK1,BAX,DCUN1D3,MYC,GPX1,CRYAB,SOD2 |
| 1.454e-03 | -6.53 | regulation of vascular associated smooth muscle cell migration | biological process | GO:1904752 | 52 | 26 | 18204 | 5365 |
TERT,MEF2C,MIR34A,MIR424,MIR448,MIR135B,ADAMTS1,MIR15A,MIR143,MIR223,NFE2L2,MIR137,MDM2,MIR638,ADIPOQ,MIR1298,MIR218-1,MIRLET7B,MIR503,MIR221,MIR21,MIR140,MIR146A,MIR182,MIR214,MIR20A |
| 1.455e-03 | -6.53 | TCF4 (transcription factor 4) | protein interactions | 6925 | 290 | 105 | 19454 | 5460 |
EXOC8,ARMC7,MYC,PBLD,HNRNPC,SMARCE1,TMEM213,ZDHHC24,NCKAP1,RABIF,MAD2L2,CMTR1,CTBP1,FRS3,PPARG,ACTL6A,MORN4,CDKN1A,LMO4,SRSF2,CYFIP2,HAND2,XRCC5,GPHN,EMG1,DDX5,EP300,STAMBPL1,SLC39A13,POU5F1,ARMC8,ATG9A,CTNNB1,EGLN3,TCF21,PPIA,HMG20A,STK16,CKS1B,JUN,SPG21,PSMA1,CHCHD2,LASP1,TCF23,TAPBPL,ALKBH4,DNTT,MRFAP1L1,CDKN2C,HSD17B8,FERD3L,CDC73,EXOSC1,CSK,OLFM3,GORASP2,AR,MAGOHB,CD47,FAH,NECTIN2,HEXIM2,COA5,UBASH3B,UBE2I,TRIM24,TRIM68,SDCBP,JUP,CHIC2,CCNH,MRPL10,KDM1A,SGF29,SMCP,VPS28,UTP23,PSMG2,TRAPPC2L,NXT2,SMG9,ID1,ZNF688,KLHL32,RNF14,TLE1,PPP1R18,TWIST2,EPHB6,EIF4E2,GUCD1,ID4,HBP1,MSRB3,TP53,MLLT6,GNG10,TSSC4,BACH1,STX11,TCEA2,CPNE2,EFHC1,TAL2 |
| 1.460e-03 | -6.53 | AHNAK2 (AHNAK nucleoprotein 2) | protein interactions | 113146 | 131 | 53 | 19454 | 5460 |
HUWE1,RPL3,DDR1,ZYX,CYB5B,RAB4A,CTSA,ACTR1A,GABARAPL1,UBIAD1,NCSTN,ISG15,TOP3B,CAV1,TSPO2,CDK9,STX6,TOMM70,SUMO2,DYNC1I2,TNFAIP8L2,SPPL3,NRSN1,AGPAT1,YWHAB,AGR2,ZCCHC9,RHOG,YWHAH,YWHAG,STAU1,EMC1,CERS2,HSPA8,PML,FAM3C,STX17,GABARAPL2,PCK2,VIRMA,DYRK1A,CYBC1,VAMP3,NRP1,PSMD14,USP14,PYCR2,SFN,RAB11A,GRB10,LMO2,MYC,EMILIN1 |
| 1.461e-03 | -6.53 | SEC24B (SEC24 homolog B, COPII coat complex component) | protein interactions | 10427 | 234 | 87 | 19454 | 5460 |
SEC61B,LMBR1L,ESR2,B4GALT3,MYC,OST4,CUL3,RAB11A,KCNA3,NTRK3,BRCA1,RAB5A,EP300,STX7,OTULINL,YIPF5,BET1,GJA1,TSG101,EED,TRAPPC10,EGLN3,YWHAH,YWHAG,XPO1,CTNNB1,RAB5C,RNF139,SLC39A7,TMT1A,SAR1B,ARL5B,EPHA4,TRIM37,TOP3B,NAA15,KLHL12,STIM1,RPN1,RAB4A,B4GALT1,QSER1,PTEN,CCNF,SMAP2,VIRMA,RAB2A,SEC13,TMEM255A,EPHA2,IGF2BP1,SYVN1,RAB9A,DERL1,SLC39A9,PML,ST7,FUT8,UBE2M,SCLT1,RPA2,SSR1,FGFR1,SEC23A,PTPN1,TMPO,STX6,CAV1,CAND1,LAMP3,DPP4,SLC25A46,SSX2IP,STYK1,KCNJ10,TRAPPC2L,NTRK2,IGF1R,DDR1,GARRE1,CAPZA1,RAB3B,HNRNPK,TNRC6C,INSIG2,FURIN,RAD23B |
| 1.463e-03 | -6.53 | regulation of membrane permeability | biological process | GO:0090559 | 73 | 34 | 18204 | 5365 |
MIR29C,VDAC2,BLOC1S2,NAIF1,BCL2L1,MUL1,TP53,BOK,IER3,BAK1,GSK3A,SLC25A4,BAX,PMAIP1,MIR142,SLC25A5,CNP,ACAA2,BAD,MIR29A,PPM1K,BNIP3L,MIR17,F11R,TMIGD1,GCLC,HSPA8,ATP5IF1,CLDN3,TMEM14A,SLC25A31,SLC35F6,PPIF,MIR146A |
| 1.466e-03 | -6.53 | establishment of vesicle localization | biological process | GO:0051650 | 171 | 69 | 18204 | 5365 |
TRAPPC10,EXOC3,EXOC1,DNM2,SNAP23,CUL3,PICALM,BLOC1S5,RAB3A,KIF1C,TRAPPC1,PSEN1,EXOC5,TRAPPC3,EXOC8,SYT4,AP3S2,CCDC186,ACTN4,TRAPPC6B,EXOC2,SYBU,SAR1B,ARL6,MKKS,TFG,AP1AR,TRAK2,TSG101,CDR2L,STARD3NL,STXBP1,COPS5,RAB27A,WDR11,BLOC1S3,TESK1,TRAPPC4,FAM91A1,SNAPIN,FBXW11,RAB1A,MREG,TRAPPC6A,RAB11B,CDK5,WASL,NDE1,TRAPPC13,TRAPPC2L,TMED9,SNAP91,SNAP25,TRIM46,SNAP29,PREB,PPFIA2,NLGN1,PAFAH1B1,ARFGAP3,BLOC1S2,BBS5,KLHL12,DYNC1I1,CEP19,YKT6,RAB11A,KIF3B,CTNNB1 |
| 1.471e-03 | -6.52 | myeloid cell differentiation | biological process | GO:0030099 | 295 | 111 | 18204 | 5365 |
IREB2,NCAPG2,MEF2C,VEGFA,CBFB,BAP1,SFXN1,SRP54,IL15,EPO,TYROBP,PDE1B,LYAR,OSTM1,CD81,PSEN1,INHA,CD4,PPARG,RACGAP1,UFL1,LIPA,IFI16,CHMP5,IL4,MYD88,ZBTB16,TCTA,MAEA,RUNX1,KLF1,TRIM10,PIK3R1,PRDX3,CDC42,MMP9,SFRP1,CREB1,MITF,GP9,SNX10,IFNG,GLO1,RPS14,FOXP1,PAFAH1B1,TLR4,SLC48A1,PTPN11,CSF2,SMAD5,LARGE1,VPS33A,RAC2,NKAP,JUNB,SLC25A5,RB1,SNRK,IRF8,TOB2,FOSL2,CDK5RAP3,TIRAP,PML,SLC11A2,JAK2,FOS,HCLS1,STAT5A,BPGM,TGFBR2,VPS54,IRF4,CCL19,LTBR,ATP5IF1,CEBPG,KIT,NDP,TRAF6,TSPO2,G6PD,TLR2,DHRS7B,JAGN1,TFRC,PRKX,TF,TMOD3,RHAG,CTNNB1,RBPJ,CLPB,UCP2,TNF,EP300,NOTCH2,LBR,BATF,HDAC6,HSCB,CCR7,PKNOX1,ITGB8,FAM20C,MPIG6B,PIR,EPHA2,BCL6,CEBPE |
| 1.473e-03 | -6.52 | TENT4B (terminal nucleotidyltransferase 4B) | protein interactions | 64282 | 134 | 54 | 19454 | 5460 |
RPA3,EXOSC4,DGCR8,NPM3,STAU1,RPL4,COIL,UTP23,TOMM22,EHD1,RPA2,RPLP0,ZNF574,RTF2,MACROH2A2,NUDT18,ZNF330,PRKRA,FGFBP1,RPL37A,RPL35,MED17,RPL13A,TENT4A,ZCCHC7,SNRNP40,ESR2,VIRMA,MYC,RPL7A,ZNF668,ZSCAN25,PEA15,RCL1,H1-1,RPL31,BCL7B,PPAN,RPL3,KRAS,UNC119B,RPL28,RPSA,H1-3,RPL8,SRP14,SRSF1,KRR1,ARL4D,LYAR,SURF6,RSBN1L,RPS2,MPHOSPH6 |
| 1.473e-03 | -6.52 | GIT2 (GIT ArfGAP 2) | protein interactions | 9815 | 134 | 54 | 19454 | 5460 |
RAC2,KRT8,RPRD1A,SMAD3,HMG20A,NUF2,YWHAG,YWHAH,EXOC1,TAX1BP3,KXD1,UBXN6,MOV10,MED4,RHOG,NME2,NCK1,RABGGTB,TFPT,PFDN1,RIGI,RCVRN,ZNHIT1,MAX,VPS33A,PHF21A,NFKBIB,TRAF1,RHOJ,TSN,PROX1,TNFAIP3,FGFR1OP2,RUSC2,CCHCR1,ICAM1,NCKIPSD,POLR1B,SPOP,LMNB1,RHOU,ARHGEF6,TGFB1I1,SKP1,FBXW7,OIP5,STAU1,CDC42,ATG16L1,LPXN,SH3GLB2,GIT2,PAK2,GOLGA5 |
| 1.473e-03 | -6.52 | SLU7 (SLU7 homolog, splicing factor) | protein interactions | 10569 | 134 | 54 | 19454 | 5460 |
THAP1,CD2BP2,PPIL3,SUPT5H,ARFGEF1,CCT5,DHX38,RBM12,CHMP4C,FHL3,BAG2,ZC3H11A,HNRNPA2B1,RPL31,ASF1A,KRAS,TSSC4,HNRNPA1,XPO1,ZCCHC10,DDX23,CWC15,SNX18,SNRPA1,INA,UBA52,SF3A1,AGGF1,RPA2,LMNA,PML,SNRPA,DDX39B,RPA3,COIL,KDM1A,HNRNPA0,GTF2I,CEP70,CCDC85B,HNRNPC,PRMT6,MYC,PPIG,UBE2H,RC3H2,PHKB,PRMT5,EIF4A3,ZNF330,SNRPB2,APEX1,ESR2,SNRNP40 |
| 1.473e-03 | -6.52 | ALAS1 (5'-aminolevulinate synthase 1) | protein interactions | 211 | 134 | 54 | 19454 | 5460 |
RCHY1,SSBP1,GATD3,FAHD1,RAP1B,AGK,SUMO2,MTRF1,GRSF1,MOV10,CHCHD1,ZNF175,MRPS26,TCEA2,S100B,HSPD1,COX8A,CDK5,HINT2,KRAS,DUSP19,FASTKD5,MRPL11,SNX20,TMSB10,PDHA1,NDUFS6,CERK,GFM2,TMSB4X,CCDC90B,TACO1,TMOD3,SNRPB2,PMPCA,MTG2,AUH,CAP2,TTC23,TUFM,OXTR,MCAT,CCHCR1,CDC73,EXD2,GRXCR1,GFM1,HSCB,POLDIP2,PCK2,CDKN1A,NUDT3,MTRES1,STAMBP |
| 1.473e-03 | -6.52 | H2AB3 (H2A.B variant histone 3) | protein interactions | 83740 | 134 | 54 | 19454 | 5460 |
H2BC11,RPL26L1,H2AB1,RPS15,BRIX1,MRPS7,RBM23,PPM1G,NLE1,H2BC12,FYTTD1,H1-10,ZCRB1,RBM27,FTSJ3,MRPS25,NSA2,NOP16,ZNF668,PELP1,RPS3,ZNF22,LIG3,PARP2,MRPS28,MACROH2A1,MRPL13,RPL18,H1-3,LBR,PAIP2B,H1-6,RPS13,MRPS18C,MEPCE,RPL17,SSRP1,MRPL52,NKRF,RPL3,DDX50,MRPL9,APOBEC3F,RPS10,RPS16,RPL7,DKC1,SURF6,CETN2,MRPS9,KRR1,YBEY,RPLP2,HP1BP3 |
| 1.481e-03 | -6.52 | CALD1 (caldesmon 1) | protein interactions | 800 | 231 | 86 | 19454 | 5460 |
CACYBP,TMPO,HNRNPL,PRNP,SPTAN1,RPLP1,TES,SHC1,HDAC6,CSNK2A1,COPS5,ACTR3B,GAPDH,CNOT2,PDIA3,RPS4X,RPL28,FLOT1,CAPZA1,DYNC1I1,VDAC1,ASF1A,MYO1B,PPP1R12A,TOP2B,ATF3,NUPR1,TFRC,ACTR2,NME1,ARPC3,DISC1,CAPZA2,PDHA1,LBR,ACTN4,ISG15,RPS7,TP53,FAM162A,VIRMA,DYRK1A,RPL22,LDHA,TMOD3,DAPK3,ACTB,PHAX,MSN,VAMP3,CTTN,HSP90AA1,OAT,ATP1A1,VMP1,BICD2,BTF3,PPP1CC,AKT3,MYC,TM9SF4,RAB11A,SAP18,HSPA5,AIF1L,STAU1,HSPA8,ARPC2,RPA3,BAP1,HIRA,PML,SPECC1L,RPLP0,TMOD1,WTAP,DCTN4,RPA2,CDK1,METTL14,PPP1CB,SEC62,CFTR,EFHD1,RBFOX2,SPTBN1 |
| 1.481e-03 | -6.51 | vitamin metabolic process | biological process | GO:0006766 | 103 | 45 | 18204 | 5365 |
SLC23A2,SLC2A3,CYP2R1,NPC1L1,CYP27A1,SLC2A1,SHMT1,UBIAD1,RBP2,AKR1B1,MMADHC,CYP4F12,MTHFD2L,GCLC,FGFR1,SLC5A6,CYP26A1,AASDHPPT,SLC19A3,THTPA,AKR1A1,ALPL,CYP27B1,LRAT,SLC25A42,FGF23,FOLR1,CBR3,GGCX,SLC19A2,ATP1A2,MMAA,CYP1A1,SLC52A3,LIPA,GSTO1,TKTL1,SLC25A32,MMACHC,MTHFS,RGN,VKORC1L1,GSTO2,NQO1,PNPO |
| 1.484e-03 | -6.51 | QRICH1 (glutamine rich 1) | protein interactions | 54870 | 137 | 55 | 19454 | 5460 |
SELENOV,PRELID1,EGLN3,NUP35,SP2,EEF1AKMT3,LBX1,DDX1,MOV10,UBXN6,GSTM3,RBM17,HSPB8,LASP1,MDC1,PAX6,SEPHS1,IMMP2L,ZYX,ACTL9,BAG2,FHL3,KHDC4,GCHFR,NUDCD3,TRAF2,SIAH1,SNRNP40,TRAF1,ESR2,RABIF,LMBR1L,ENO1,CIB2,ATG3,OSGEP,NFYA,SEC13,NTAQ1,GGH,ZDHHC17,RPA3,ACTMAP,IDH3A,PML,HSPA8,HADHA,TOX4,SRARP,ACACA,LPXN,SNRNP27,RFXANK,LMO4,LMO3 |
| 1.484e-03 | -6.51 | AP1G1 (adaptor related protein complex 1 subunit gamma 1) | protein interactions | 164 | 137 | 55 | 19454 | 5460 |
RAB1A,AKT2,HNRNPA2B1,BAALC,AP1M1,TP53,GBE1,JUN,NECAP2,NECAP1,AP1S2,AP2S1,COMT,FBXO32,AFTPH,ARF6,ATG9A,GPRASP2,XPO1,SMAD4,FKBP4,AGR2,RPA3,DVL2,PML,PSEN2,HSPA8,RAB5A,EP300,NPM3,FBXW7,STAU1,PYGB,PRKAB1,PAFAH1B1,ARHGAP1,SYNRG,AP1AR,RPA2,CCNF,ARF1,TRMT6,CREB1,LMBR1L,SMAP2,TNFRSF1B,AP2M1,AP1G2,ESR2,CAP2,MYC,TUFM,SPOP,SYP,LAMTOR1 |
| 1.486e-03 | -6.51 | endosome organization | biological process | GO:0007032 | 92 | 41 | 18204 | 5365 |
TSG101,ATP6V1A,ATP6V0B,UBAP1,CHMP2A,SNX10,RAB22A,USP8,HGS,CHMP2B,PLEKHJ1,VPS18,TMCC1,RAB27A,RAB11A,CHMP1A,PLEKHF2,VPS4A,STX6,TMEM127,LAMTOR1,CORO1C,FHIP1B,VTA1,CHMP5,ATP6AP2,VPS28,PHETA2,CHMP1B,SNX3,EXOC8,CHMP4C,AQP11,ATP6V1D,SNX33,VPS4B,FASLG,SQSTM1,PLEKHF1,RNASEK,RNF26 |
| 1.486e-03 | -6.51 | DOCK9 (dedicator of cytokinesis 9) | protein interactions | 23348 | 57 | 27 | 19454 | 5460 |
CLK1,NUCKS1,KRAS,HSPA5,RPS27A,TOP3B,LBR,SNAPIN,CDC42,HEXIM1,SMAD3,RAB35,HRAS,RAC2,PPP2R5E,FBXO22,RHOJ,VIRMA,APEX1,YWHAH,YWHAG,RHOB,YWHAZ,CIRBP,RHOG,YWHAB,SMAD2 |
| 1.486e-03 | -6.51 | TOM1L2 (target of myb1 like 2 membrane trafficking protein) | protein interactions | 146691 | 57 | 27 | 19454 | 5460 |
RAB9A,RAB5A,BAP1,WBP2,RNF11,AHCYL1,RIGI,TOLLIP,IGBP1,DSTN,CREB1,LMBR1L,DFFA,SIN3A,S100A6,SRXN1,SMURF1,CAV1,ESR2,PRNP,XPO1,AR,BAG3,WWP2,SERPINH1,LAMTOR1,MYO6 |
| 1.486e-03 | -6.51 | EVI5L (ecotropic viral integration site 5 like) | protein interactions | 115704 | 57 | 27 | 19454 | 5460 |
SIGLECL1,TOP3B,NPY2R,SEC62,FAXC,HCST,FAF2,AP1M1,PSEN2,CXCR4,SOS2,RBM7,BRD3,FIS1,GPR17,RAB11A,GAS8,XPO1,P2RY10,HNRNPL,SPPL3,RAB11B,SRPK2,PRPF18,ILVBL,NUDT18,SSR2 |
| 1.486e-03 | -6.51 | ICAM2 (intercellular adhesion molecule 2) | protein interactions | 3384 | 57 | 27 | 19454 | 5460 |
RAB29,ITM2B,C1QL1,TEX264,ATP2C1,RUSF1,BSCL2,ACVR1B,MFSD3,RAB3B,SACM1L,RAB18,DAD1,FUT8,TUBA1A,RPN1,CD209,TM9SF1,MSN,ARL6IP5,MAD2L2,TM9SF4,CNNM4,HFE,ATP1A3,SLC20A1,NRP1 |
| 1.487e-03 | -6.51 | ALDH1B1 (aldehyde dehydrogenase 1 family member B1) | protein interactions | 219 | 179 | 69 | 19454 | 5460 |
DNAJC7,PDCD10,RNF139,RHOG,TRAF6,SLC25A28,YWHAG,YWHAH,GAPDH,FEM1B,PDIA3,RPL6,CDK9,EGLN3,ESD,ELK1,HSP90AB1,MARCHF4,SNX1,TOP1,RNF128,SSBP1,PHB1,SOD2,CBX3,PDHA1,PPP2R1A,FAF2,UBR7,PGM1,TXNRD1,RANBP1,HEXA,XPNPEP1,ETFA,HINT2,COX8A,HSPD1,PFDN4,OAT,UBE2H,YWHAZ,LMNB1,RHOB,TUFM,MTG2,MYC,NDUFB10,PTPN11,LDHB,CUL3,UQCRQ,SH3BGRL,LDHA,TRIM29,SMU1,UQCRC2,CCNF,HEXB,HEXIM1,DCTN4,DHRS4,CFTR,SUFU,PAFAH1B1,GRPEL1,PYGB,UCHL3,RER1 |
| 1.489e-03 | -6.51 | protein kinase complex | cellular component | GO:1902911 | 150 | 61 | 19108 | 5553 |
GTF2H4,CCNA2,CSNK2A1,CDK12,TBK1,GTF2H2,ATG101,DAPK1,TBC1D5,CAB39,PYCARD,CKS2,CDK8,CDK7,CCNY,ACVR1B,CDK6,CCNB1,CDK5R1,PHKA1,RB1,PARD6A,CDKN2D,CDK4,CDK5,CCND1,CDKN1A,RB1CC1,PHKG1,PRKAG1,MNAT1,IGF1R,STK11,CCNQ,CCNF,ACVR1C,TGFBR2,IKBKB,ACVR1,CDK9,STRADB,AZI2,CSNK2B,PCNA,BCCIP,PRKACB,TANK,CCND3,C9orf72,CCNI,SESN2,AKAP14,PRKAB1,PHKB,XRCC5,CCNH,CDK1,CKS1B,ERCC3,CNPPD1,GTF2H5 |
| 1.489e-03 | -6.51 | organophosphate metabolic process | biological process | GO:0019637 | 926 | 314 | 18204 | 5365 |
SOCS2,SLC25A1,G6PC3,PGAP3,PLA2G4B,CDIPT,ALDH1L1,AGPAT1,ABHD6,IER3,NDUFB6,MTMR6,HACD2,SUCLG2,ABHD4,MMUT,NUDT18,FITM2,ACSL4,STOML2,FBP2,DNAJC30,RAB23,FMO2,CASK,UCK2,GDE1,GPD2,UPRT,GLYAT,IMPA2,SULT1B1,NDUFB7,SOCS4,PDE7A,NDUFA12,AGPAT5,DLAT,HTR2A,ENO1,INPP5K,ISYNA1,PNP,ATP5F1A,GGPS1,NDUFS8,SMPD2,NDUFS3,ACOT6,NUS1,PNPLA8,NME4,PIGW,ACP6,LDHB,NUDT19,AK2,ELOVL7,ENTPD3,DCTPP1,DCAKD,ATP6V1A,REXO2,ADCY3,SOCS3,ADSS2,PC,GFPT1,MTM1,PLPP6,SRD5A3,DTYMK,LPCAT3,SLC19A2,OCRL,MDH1,ATP5PO,GUK1,OGDHL,MFN1,ABHD12,NDUFC2,PRPSAP1,SOCS5,NUDT5,ORMDL1,PCK2,PLCB1,PGAP2,ATP5PD,INPP5E,NUDT2,HYCC1,PRPS1,ATP5F1B,NPR2,KARS1,GK5,OSBP,ATP5MG,PIP4P2,CRYL1,PIK3R3,UCP2,SGMS1,PDE1A,UQCC3,RPIA,PLSCR3,FKRP,PFKFB2,SULT1A3,PDHB,PLA2G15,OLA1,FMO1,PGAM1,ABHD14B,PDE8A,GDPD3,LDHA,NDUFA1,ACACA,IDH1,BAD,DCK,SLC19A3,ADCY2,ATP5MC1,SLC25A10,AKR1A1,DNPH1,PLA2G5,PCSK9,NR1H2,PTEN,PIP5K1A,CKB,DLG1,MVD,RPE,ETNK2,NDUFA2,ATP1A2,PLAA,ATP1B1,TP53I3,HYCC2,BECN1,ATP5PF,TECR,PLA2G12A,DOLK,PNPO,GPX4,DHRS7B,CNP,GNPAT,PGAP4,SERINC1,DLST,FHIT,NDUFV2,PGM1,FIG4,HADHA,GMPS,NDUFS2,GNAI3,ADK,IDO1,NUDT4,ATP5PB,PIK3CA,PIGC,NMRK1,ELOVL3,PAFAH1B1,IDH2,MPP1,PIK3CG,SORD,VAC14,PDE4B,ENO2,ATP5MC3,IP6K1,INPP4A,PIP4P1,COX11,PLCB2,HSPA8,ACSS2,NT5C3A,MTMR2,NDUFAB1,NDUFB10,TMEM38B,NME1,MTHFD2L,PLPP4,HEXB,CMPK1,FAR2,PLAAT5,SMUG1,OSBPL8,SAMHD1,AK3,ATP5F1E,HMGCS1,GPHN,ALPL,MECP2,FABP5,RRM1,HACD1,GAPDH,NUDT16,SACM1L,PLPPR1,NDUFB4,HINT1,CLN8,PTDSS1,TAMM41,PGS1,NUDT7,PAPSS2,NDUFB8,AK5,PIGY,LIPA,ELOVL4,SLC52A3,PGK1,TNFAIP8L3,PIGK,SLC30A5,HDHD5,SLA2,NDUFS6,PIK3R2,PDE9A,SDHC,BPNT2,RAN,PIK3R1,NQO1,ABHD16B,GPAM,GPAA1,PPT1,UCKL1,SARM1,SHMT1,PLAAT3,NT5C2,FITM1,FBP1,ABHD5,NDUFA5,DPM2,GTPBP1,NME2,ATP5MK,PRDX6,PCYT1B,EPHA2,CISH,MTMR12,GK2,PPAT,ORMDL3,FDFT1,OGG1,PTPMT1,ELOVL1,TYMS,NUDT3,THTPA,PIGA,GUCY1B1,TAFAZZIN,CACNB4,ATP5F1D,NDUFB5,NUDT9,PDE2A,DCTD,ELOVL6,SPHK2,UCK1,UGP2,INPPL1,NPPC,CLPX,ACOT8,UMPS,BPGM,ACAT1,PLSCR1,SDHB,PTHLH,PIP4K2C,ENTPD4,G6PD,SELENOI,CHKB,TPST1,PDHA1,NUDT12,SGMS2,CD38 |
| 1.490e-03 | -6.51 | NGF signalling via TRKA from the plasma membrane | REACTOME pathways | R-HSA-187037 | 387 | 149 | 10285 | 3229 |
LAMTOR2,KIT,PPP2CB,HRAS,GAB1,IL5,PIP4K2C,PSMD1,PSMB2,PIK3CA,PEA15,AKT1,PSMA6,AKT3,FGF16,IL2RB,CAMK2G,LAMTOR3,VWF,RALA,IER3,PSMC1,CUL3,PSMC3,TP53,CD86,PSMA1,RPS27A,IL3,PHB1,PSMD4,SPRED1,SHC1,RASGRP3,DUSP3,PSMB4,SEM1,DUSP1,MET,PAQR3,FGF23,PTEN,PSMA5,SPTAN1,PDE1A,AP2A1,PPP2R5E,PIP5K1A,PEBP1,PSMB3,IL2RG,PIK3R2,ELK1,ICOS,MDM2,YWHAB,DUSP6,FGF1,PPP2R5A,RALB,RAP1B,MAP2K1,KRAS,FGF22,UBA52,WDR83,RAF1,TNRC6C,RIT1,FRS3,PSMD10,SRC,DUSP9,MOV10,PIK3AP1,FGF10,AP2S1,AKT2,AP2M1,SHC3,MEF2A,RAP1A,ATF1,CDKN1A,PRKCE,PIK3R3,CSF2,MAPKAPK3,JAK1,FGF7,PSMD12,GSK3A,MAP3K11,BAD,DUSP10,DNAL4,NEFL,FGF3,PSME2,PSMD6,HBEGF,PSMB9,SPRED2,IL2RA,DNM2,PSMA4,PSMB11,IL2,FGFR1,PSMC5,PSMB10,NTRK2,PSMB6,PSMA2,ADCY2,DLG4,CD28,CSK,BRAP,PSMD3,CREB1,PSMB7,JAK2,PIK3R1,CRKL,AHCYL1,PSMB1,PSMB5,PSMA3,ADCY3,CDKN1B,PSMC4,PSMD14,MEF2C,PTPN11,PRKCA,PRKACB,UBB,PPP2R1A,RIT2,SPTBN1,AGO1,PPP5C,PDE1B,PSME1,ANGPT1,PSMD7,CD80,FGF17 |
| 1.492e-03 | -6.51 | SLC35A5 (solute carrier family 35 member A5) | protein interactions | 55032 | 19 | 12 | 19454 | 5460 |
TNKS2,FKBP8,SACM1L,RNF208,TNKS,RHOB,LGALS8,TMEM100,DDX39A,CSGALNACT2,SLC41A1,ACTL6B |
| 1.492e-03 | -6.51 | MCOLN1 (mucolipin TRP cation channel 1) | protein interactions | 57192 | 19 | 12 | 19454 | 5460 |
PTP4A3,VDAC2,TRIM27,APPBP2,ATG3,GPR35,EDEM1,CSGALNACT2,SEC22A,SLC35E1,CCR6,CLEC2B |
| 1.492e-03 | -6.51 | LRRC52 (leucine rich repeat containing 52) | protein interactions | 440699 | 19 | 12 | 19454 | 5460 |
LRRC3,MIA2,HAPSTR1,EFNB1,SRPK2,CD151,DIPK1A,TMEM219,FAM3C,OR10A4,NRN1,TMEM59L |
| 1.492e-03 | -6.51 | SPIRE2 (spire type actin nucleation factor 2) | protein interactions | 84501 | 19 | 12 | 19454 | 5460 |
TMOD3,PRNP,ACTB,TOP3B,SFN,RAB11A,YWHAH,BCL7C,YWHAG,YWHAZ,HGS,YWHAB |
| 1.492e-03 | -6.51 | CDH3 (cadherin 3) | protein interactions | 1001 | 19 | 12 | 19454 | 5460 |
SMAD4,JUP,GRB10,TAX1BP3,CFTR,CTNNB1,GPC1,ELK1,CTNND1,CTNNA1,PTEN,AP2M1 |
| 1.492e-03 | -6.51 | ZNF215 (zinc finger protein 215) | protein interactions | 7762 | 19 | 12 | 19454 | 5460 |
HSPA8,TRAPPC1,VIRMA,VTA1,UBB,LRRC40,ZSCAN1,ZNF24,HECTD1,HERC4,HSP90AA1,SCAND1 |
| 1.492e-03 | -6.51 | Snap29 (synaptosomal-associated protein 29) | protein interactions | 67474 | 19 | 12 | 19454 | 5460 |
BET1,SEC22B,VTI1B,RAB11B,VAMP8,ROCK1,STX7,STX6,RSRC1,STX8,STX5,STX10 |
| 1.494e-03 | -6.51 | CTPS1 (CTP synthase 1) | protein interactions | 1503 | 176 | 68 | 19454 | 5460 |
UBE2H,RIT1,TXNIP,BRCA1,GMPS,RUNX1,CUL2,CUL3,MYC,SUGP1,ESR2,VIRMA,PPP5C,RPGRIP1L,SNX3,TSN,FBXO22,CFAP298,PRMT5,METAP2,CCNF,PIH1D1,RTF2,EIF4B,RPA2,CFTR,GABARAPL2,NEK7,PPP1CB,MRPL20,GINS3,STAU1,UFL1,SQSTM1,PSMA3,EXOSC4,HSPA8,PML,BAP1,LCA5,RPA3,PDCD10,PSMD7,TRAF6,DDRGK1,YWHAG,COPS5,H2AC14,EGLN3,TMPO,SNX2,SPPL3,CAND1,FBXO32,PHB1,DFFA,MOB3C,EZH2,MAP2K3,MAP1LC3B,ACO1,RAD21,DCTPP1,TTC4,KRAS,NEDD8,HSD17B10,GLUL |
| 1.494e-03 | -6.51 | NIP7 (nucleolar pre-rRNA processing protein NIP7) | protein interactions | 51388 | 176 | 68 | 19454 | 5460 |
SRPK2,RPL10,ESR2,RPL22,TUBB,RPL35,PRKRA,RPL37A,UBE2H,RIT1,DNAJB6,LMNB1,RC3H2,ATG3,ZNF668,THAP7,DNAJC8,PPP1CC,MYC,RPL7A,RAB11A,COIL,DGCR8,NPM3,NOP53,FBXW7,RPL4,STAU1,RNF113A,RPA3,RPLP0,MACROH2A2,RPA2,APOBEC3C,GTF2H4,BET1,ZBTB2,RPS16,LYAR,RPL8,SRP14,CBFB,KRR1,LHX2,RPL10A,CHCHD1,H2AC4,SNRNP70,ATG7,DDRGK1,GRSF1,MRPL22,RPL28,EIF3E,RIGI,PTPN4,H3C1,ZBED1,KRAS,RPL3,SNIP1,ILF2,NUPR1,CHMP4C,AURKAIP1,HINT3,SOX2,RPL15 |
| 1.499e-03 | -6.50 | regulation of adaptive immune response | biological process | GO:0002819 | 209 | 82 | 18204 | 5365 |
IL2,CCR2,CCL19,CD46,CD81,LILRB4,KLRD1,IFNA2,CD4,MIR21,CYRIB,SOCS5,IL20RB,TNFRSF1B,TNFSF13,NDFIP1,CD1B,CD1C,IL4,TRAF6,IRF1,NLRP3,PRKCQ,B2M,CD28,CD80,LTA,IL23A,EXOSC3,MEF2C,FCGR1A,IFNB1,HMCES,JAK2,IRF7,TNFRSF14,MAD2L2,RC3H2,STX7,CLEC6A,FCGR2B,STAT6,MICB,IL6ST,CD226,TRIM27,DUSP10,BATF,PYCARD,AGER,NECTIN2,CD1A,IL18,SASH3,HMGB1,CD1D,JUNB,CD40,HSPA8,IL1B,LILRB1,CD274,FOXP3,IL12A,HFE,BCL6,HSPD1,TRAF2,SHLD1,RSAD2,CLEC7A,IL6,KMT5B,TNFAIP3,TFRC,TNF,EP300,DUSP22,IL10,IL12B,XCL1,CD1E |
| 1.500e-03 | -6.50 | organic cyclic compound catabolic process | biological process | GO:1901361 | 441 | 159 | 18204 | 5365 |
CNOT2,PDE1A,MAGOH,SLC6A3,UCP2,SARM1,DIO3,DPEP1,RBM7,NT5C2,SKIC8,GRSF1,DBH,PNRC1,EIF4A3,HNRNPD,CNOT6L,LSM2,ETF1,PDE12,ELOC,DFFA,RNASEH2C,PDE8A,LDHA,DBR1,SPP1,PGAM1,HSD11B1,EXOSC8,RNASEH1,HSD17B6,LSM4,DNASE1L1,ISG20,FKRP,PFKFB2,APOBEC3C,SULT1A3,MRTO4,PDE2A,DCTD,DNPH1,NUDT9,APOBEC3B,PELO,PPP1R8,RNASET2,STPG4,OGG1,NUDT3,PABPC1,MTHFS,EXOSC4,DIS3L,APOBEC3A,NUDT12,ENTPD4,SLCO1B3,FEN1,SLCO2B1,URAD,DICER1,VPS54,CASC3,ZCCHC7,CNOT6,BPGM,ACAT1,PYM1,CYP1A1,TRIR,CYP27A1,NUDT4,FITM2,TENT2,THRAP3,HSD17B11,APEX1,IDO1,RNASE6,NUDT18,SUCLG2,IER3,ALDH1L1,ENPP4,PGM1,AGO1,CRMP1,CYP39A1,APOBEC3G,CNP,MAGOHB,FHIT,LSM5,DDX5,NCBP2,UGT1A1,PNP,APOBEC3D,COMT,YWHAH,CNOT8,ENO1,HTR2A,PDE7A,SMG9,POLR2G,HMOX2,PDE4B,ENO2,TENT4A,CYP2F1,HNMT,NFE2L2,SNX17,HINT1,PDE1B,LSM6,MOXD1,CNOT7,RC3H2,SMG5,DCTPP1,GAPDH,CYP27B1,NUDT16,EIF3E,ENTPD3,FGF23,EXOSC1,BLVRA,YTHDF2,NUDT19,EXOSC3,SMUG1,UPF3B,DXO,EDC3,SAMHD1,AASDHPPT,PDE9A,NUDT5,DCP2,ABCC2,FAH,OGDHL,MTAP,SMG8,WDR82,APOBEC3F,CYP7A1,PGK1,LIPA,APOBEC3H,NUDT1,METTL14,MGAT1,NUDT7 |
| 1.500e-03 | -6.50 | H2AC17 (H2A clustered histone 17) | protein interactions | 8336 | 228 | 85 | 19454 | 5460 |
KRR1,H2AZ1,MRPS9,RPLP2,RPS10,CAND1,RPS16,CETN2,HMG20A,SURF6,DKC1,SPATS2L,MRPS35,DDX50,CMSS1,MOV10,BAZ1B,NGDN,APOBEC3F,COPS5,MRPL9,H2BC17,RPS2,MRPS26,MGMT,NKRF,MRPS11,RPL23A,RPL3,MRPS18B,IMP4,NOC4L,MRPS33,H1-6,NEDD8,PAK1IP1,RIGI,SSRP1,RPL17,SRSF12,MRPS18C,MRPL47,MAK16,SRP72,SART3,LIG3,PARP2,EIF2AK2,RPS3,PELP1,MACROH2A1,MRPL13,RPS20,PRKRA,TRIM29,RPF1,RSL24D1,VIRMA,NOP16,ZSCAN25,RPS17,MRPS25,ZCRB1,FTSJ3,FYTTD1,NSA2,CDKN2AIP,ELAVL2,RPS5,RPS28,PPM1G,CCDC86,H2BC12,CFDP1,MRPL40,STAU1,RPS15,MRPL17,MRPS7,AATF,PIP5K1A,RPS14,H2BC11,RPLP0,RPL26L1 |
| 1.501e-03 | -6.50 | RET signaling | REACTOME pathways | R-HSA-8853659 | 270 | 108 | 10285 | 3229 |
RAP1A,SHC3,PSMD12,JAK1,FGF7,PIK3R3,CSF2,DUSP10,NEFL,MAP3K11,PSMB9,SPRED2,IL2RA,PSMD6,HBEGF,FGF3,PSME2,DLG4,CSK,BRAP,PSMA2,PSMB6,PSMB11,PSMC5,IL2,FGFR1,PSMB10,PSMA4,PSMC4,PSMB5,PSMA3,PIK3R1,PSMB1,PSMD3,JAK2,PSMB7,UBB,PPP2R1A,PRKCA,PRKACB,PTPN11,PSMD14,PSMD7,FGF17,PSME1,ANGPT1,SPTBN1,PPP5C,PIK3CA,PSMA6,PEA15,PSMD1,PSMB2,PPP2CB,KIT,LAMTOR2,HRAS,GAB1,IL5,PSMC1,CUL3,VWF,IL2RB,DOK5,CAMK2G,LAMTOR3,FGF16,PHB1,PSMD4,SPRED1,RPS27A,IL3,PSMA1,PSMC3,DUSP1,DOK6,SEM1,PSMB4,SHC1,RASGRP3,PEBP1,PSMB3,SPTAN1,PPP2R5E,FGF23,PSMA5,MET,PAQR3,DUSP6,GRB10,FGF1,PPP2R5A,YWHAB,PIK3R2,IL2RG,RAF1,FGF22,DOK4,UBA52,WDR83,MAP2K1,KRAS,RAP1B,FGF10,SRC,DUSP9,FRS3,PSMD10 |
| 1.502e-03 | -6.50 | NUP42 (nucleoporin 42) | protein interactions | 11097 | 143 | 57 | 19454 | 5460 |
PRKRA,RPS20,SEC61B,MRPL13,RAN,HNRNPC,ELAVL2,IGF2BP1,MAPRE1,CASC3,FYTTD1,DERL1,RAB9A,RAB5A,SNRPA,NGRN,RPA3,SEC62,OTULINL,ST7,RBMS2,SF3A1,ZC3H14,RPL26L1,RPLP0,SSR1,HSD17B11,NXT1,RAC2,MRPS9,SRSF1,FUBP3,TMPO,SRSF10,NUP35,HNRNPL,COPS5,XPO1,DDRGK1,FAM20B,APOBEC3F,MOV10,ZC3H11A,RPL3,TRIM11,TMT1A,LSM14A,SRSF12,RIGI,H1-6,NUP107,CDC40,NUP153,H2AX,RANBP1,GLE1,VPS33A |
| 1.502e-03 | -6.50 | positive regulation of muscle hypertrophy | biological process | GO:0014742 | 37 | 20 | 18204 | 5365 |
HAND2,MIR21,IL6ST,BECN1,ROCK1,MEF2A,ADRA1A,MIR34C,MTPN,PARP2,ROCK2,MIR208A,IGF1,PRKCA,MIR34B,MIR214,MIR17,PPP3CA,PDE9A,MIR20A |
| 1.504e-03 | -6.50 | nucleotide metabolic process | biological process | GO:0009117 | 515 | 183 | 18204 | 5365 |
HMGCS1,SMUG1,CMPK1,FAR2,AK3,SAMHD1,ATP5F1E,HINT1,NDUFB4,HACD1,RRM1,GAPDH,NUDT16,AK5,ELOVL4,SLC52A3,PGK1,LIPA,PAPSS2,NDUFB8,NUDT7,PDE9A,SDHC,NQO1,RAN,NDUFS6,NDUFV2,PGM1,CNP,DLST,FHIT,ATP5PB,NUDT4,ELOVL3,NMRK1,IDO1,GMPS,NDUFS2,ADK,GNAI3,ATP5MC3,COX11,MPP1,IDH2,PDE4B,ENO2,NDUFB10,NME1,NDUFAB1,MTHFD2L,HSPA8,NT5C3A,ACSS2,CACNB4,GUCY1B1,NDUFB5,ATP5F1D,ELOVL1,OGG1,NUDT3,TYMS,NPPC,CLPX,DCTD,PDE2A,NUDT9,UCK1,ELOVL6,PTHLH,SDHB,ACOT8,UMPS,ACAT1,BPGM,TPST1,PDHA1,CD38,NUDT12,G6PD,ENTPD4,GPAM,SHMT1,SARM1,NT5C2,PPT1,UCKL1,NDUFA5,GTPBP1,ATP5MK,NME2,PPAT,EPHA2,NME4,LDHB,NUDT19,ACOT6,NDUFS3,ATP6V1A,REXO2,ADCY3,ADSS2,PC,ELOVL7,AK2,DCTPP1,DCAKD,MDH1,ATP5PO,DTYMK,NUDT5,PCK2,OGDHL,NDUFC2,MFN1,GUK1,PRPSAP1,IER3,ALDH1L1,NDUFB6,SLC25A1,FITM2,ACSL4,DNAJC30,STOML2,FMO2,CASK,RAB23,MMUT,NUDT18,HACD2,SUCLG2,NDUFB7,SULT1B1,NDUFA12,PDE7A,UCK2,GLYAT,GPD2,UPRT,ATP5F1A,PNP,NDUFS8,HTR2A,ENO1,DLAT,ADCY2,ATP5MC1,IDH1,ACACA,DCK,BAD,DNPH1,TP53I3,ATP1B1,MVD,DLG1,NDUFA2,ATP1A2,RPE,ATP5PF,TECR,ATP5F1B,NPR2,ATP5PD,PRPS1,NUDT2,UQCC3,PDE1A,RPIA,UCP2,KARS1,ATP5MG,PDHB,FKRP,PFKFB2,SULT1A3,PDE8A,NDUFA1,LDHA,OLA1,ABHD14B,FMO1,PGAM1 |
| 1.506e-03 | -6.50 | SH2D3C (SH2 domain containing 3C) | protein interactions | 10044 | 170 | 66 | 19454 | 5460 |
GSTP1,MET,GTF3C4,TIMMDC1,GRPEL1,SRSF2,TLCD1,PAFAH1B2,PGK1,ATP5IF1,ADK,CKB,CISD1,YWHAZ,MYO6,AR,PYCR2,PYCR1,CDC20,DEK,SRC,PRDX2,ARMC6,TXNDC12,ABHD14B,ACAT1,EIF4A3,POP7,PAFAH1B3,TMEM14B,DDX42,PPID,SLC29A1,ISG15,ACTN4,CYB5R1,TRAF2,MARCKSL1,TMEM126A,PTGES3,PRPS1,KIT,AKAP12,NEDD8,PRPSAP1,HINT2,IDH1,COTL1,HSPB1,NQO1,OSBPL8,GSTO1,YWHAG,CRIP1,RIOX2,GMPPA,PPIA,G6PD,SLC25A12,ALCAM,CCAR2,HSD17B11,LDLR,ALDH1A3,COQ8A,COMT |
| 1.507e-03 | -6.50 | HYOU1 (hypoxia up-regulated 1) | protein interactions | 10525 | 284 | 103 | 19454 | 5460 |
BET1,H1-5,GLRB,ETF1,EDEM3,PRDX3,ARMCX3,KLF3,EIF4B,TMEM106B,XRCC5,DNAJC3,AKAP1,PSMA3,LCN1,HSPA8,STAU1,PXMP2,CUL3,RAB11A,GGH,BRCA1,NTRK3,DLST,LMBR1L,SEC61B,SARM1,RMDN3,E2F4,TOP3B,B3GNT2,EEF2,NUP37,TUBA1A,CHMP4C,EZH2,CPE,DNAJB4,EWSR1,PSMA1,ENKD1,TENM3,AGR2,PHB1,SERPINC1,XPO5,RPL7,SNX1,SNX2,DNAJB9,OS9,COX14,CFTR,CDC42,CZIB,RNF103,FGFR1,RPA2,MET,PRKCA,UBE2M,SIRT7,BAP1,RAB9A,LARGE1,CLU,HSPA5,DNAJC8,DNAJC10,LACRT,SNX5,UBE2H,CALU,NAPA,NRP1,METAP2,GANAB,MGST3,DAPK1,CTSB,VIRMA,CCT5,CCDC47,APOO,H2AX,DNAJC2,HSPA13,TFRC,FURIN,C1QC,BACE1,IGF1R,DNAJC30,MSH6,EDEM1,DPP4,MOV10,GOLPH3L,DNAJC7,COX4I1,ADAM21,PLGRKT,TMPO |
| 1.507e-03 | -6.50 | GFUS (GDP-L-fucose synthase) | protein interactions | 7264 | 49 | 24 | 19454 | 5460 |
GFUS,RIOK2,XPO1,GMPS,BAG3,GALE,DHRS11,DDX1,FAIM,EFHD2,DSTN,MAT2B,NTMT1,RABIF,G6PD,EEF1A1,SOX2,STX17,PPME1,STAT6,HSPA8,ARFIP1,KLHL15,RBBP7 |
| 1.507e-03 | -6.50 | INTU (inturned planar cell polarity protein) | protein interactions | 27152 | 49 | 24 | 19454 | 5460 |
MAGED2,EED,AP2M1,HNRNPL,VIRMA,PPP5C,UBB,PSMD7,TRAPPC4,VPS4A,APMAP,APPBP2,SMC4,PSMD12,PSMC4,CCNA2,FNTB,EHD3,CNP,CFTR,ASPM,PPP1CB,VAPB,PSMC3 |
| 1.507e-03 | -6.50 | APH1A (aph-1 homolog A, gamma-secretase subunit) | protein interactions | 51107 | 49 | 24 | 19454 | 5460 |
SCAND1,GPR35,MFSD6,ERLIN2,NCSTN,RBFOX2,RIGI,PSEN1,APH1A,PSENEN,BHLHE40,PSEN2,SLC39A9,FIS1,FXYD6,FAM241A,ATF4,TLE1,SLC38A7,MOV10,CREB3,MPP1,ANKRD46,LMBR1L |
| 1.507e-03 | -6.50 | Mdm2 (transformed mouse 3T3 cell double minute 2) | protein interactions | 17246 | 49 | 24 | 19454 | 5460 |
WDR77,RPS14,TP53,CCT5,RPS7,XRCC5,RPL3,TRIM21,HADHA,HNRNPF,HMGB1,HNRNPK,STK38,THRAP3,STK38L,CCT2,PIP4K2C,RPS2,YWHAB,RPL9,RPS9,RPS10,TCP1,CDK9 |
| 1.507e-03 | -6.50 | PTGFRN (prostaglandin F2 receptor inhibitor) | protein interactions | 5738 | 49 | 24 | 19454 | 5460 |
SLC25A17,SKP1,RMND1,VIRMA,SIAE,CD151,CLEC12B,LGALS3,ST8SIA4,LMBR1L,OPTN,CD63,DNAJB6,HFE,SMAD4,SDF2L1,LGALS8,CD9,SFTPC,SCGB1D1,CD81,TMEM106A,FUT8,RPL6 |
| 1.507e-03 | -6.50 | MPI (mannose phosphate isomerase) | protein interactions | 4351 | 49 | 24 | 19454 | 5460 |
RPA2,NECAP1,SERPINA3,NECAP2,CFTR,NEDD8,HSPE1,SRI,SAR1B,RPA3,SOD1,FAS,RIT1,KLHL9,CUL3,GMPPB,P2RY10,TIA1,MIF,SUMO2,CCNF,OPTN,FBXO32,PITPNB |
| 1.511e-03 | -6.50 | SCFD2 (sec1 family domain containing 2) | protein interactions | 152579 | 36 | 19 | 19454 | 5460 |
USE1,STX12,SCFD1,NAPA,VAMP5,BET1,SEC22B,DDX39A,OTULINL,DNAJC25,TYW3,HSCB,DNAJC1,NAPG,VIRMA,FKBP8,HS2ST1,RINT1,STX18 |
| 1.511e-03 | -6.50 | CCL26 (C-C motif chemokine ligand 26) | protein interactions | 10344 | 36 | 19 | 19454 | 5460 |
CXCL14,THUMPD1,CXCL9,CCL2,CXCL11,KIAA0232,CCR3,CXCL10,PAX6,CCL8,CCL17,GGPS1,XCL1,CXCL12,CCL28,CCL11,CCL5,CCL21,CCR1 |
| 1.511e-03 | -6.50 | SLC11A2 (solute carrier family 11 member 2) | protein interactions | 4891 | 36 | 19 | 19454 | 5460 |
RHOG,RHOB,LAMP3,CDC42,HACD2,LAMP2,SLC25A17,PXMP2,UQCRH,KRAS,RER1,RHOJ,LGALS3,NDFIP1,GPR89A,RAB9A,RAC2,HRAS,ATP2B4 |
| 1.511e-03 | -6.50 | PEX7 (peroxisomal biogenesis factor 7) | protein interactions | 5191 | 36 | 19 | 19454 | 5460 |
CCT7,KDM1A,PEX13,TCP1,PHYH,CFAP298,ACAT1,TFPT,PEX5L,CCT8,PFDN2,PDCL,PFDN6,CCT2,RETSAT,PFDN5,KLHDC8A,CCT5,PRMT6 |
| 1.511e-03 | -6.50 | TIFA (TRAF interacting protein with forkhead associated domain) | protein interactions | 92610 | 36 | 19 | 19454 | 5460 |
NUDT18,DVL2,RPL9,HIRA,BIRC2,TIFA,ARHGEF39,AP1M1,TRAF1,LNX2,TNFAIP3,TRAF2,DDX39A,NTAQ1,H2AX,NIF3L1,SDCBP,TRAF6,TNFAIP8 |
| 1.511e-03 | -6.50 | DDX52 (DExD-box helicase 52) | protein interactions | 11056 | 167 | 65 | 19454 | 5460 |
RAC2,EED,KRR1,WIF1,CAND1,DDRGK1,COPS5,PMP22,DPP4,IFI16,LHX2,MPHOSPH10,SNRNP70,H2AC4,DDX23,RPS24,FGF3,RPL31,PTGES3,IMP4,NOC4L,H3C1,KRAS,H1-6,SOX2,AURKAIP1,RAF1,RHOBTB1,RPL18,FGFBP1,ZNF330,ZNF22,LMBR1L,ESR2,SRPK2,RHOJ,SNRNP40,PPP1CC,ZNF668,MYC,RIT1,H1-1,CDKL2,CHCHD4,RHOB,RC3H2,PSKH1,RAB5A,SIRT7,RPA3,AATF,UTP23,COIL,FBXW7,RPL4,STAU1,CDK7,RND2,CDC42,EDF1,CCND1,BET1,GRM2,PPARG,RPA2 |
| 1.512e-03 | -6.49 | GFPT1 (glutamine--fructose-6-phosphate transaminase 1) | protein interactions | 2673 | 149 | 59 | 19454 | 5460 |
RNF126,OTULIN,PPP2R1A,MTCH2,TRIM6,RAF1,G3BP1,KRAS,DCP2,CCT8,HSPB1,AHSA1,AGR2,CTNNB1,XPO1,HDAC6,WWP2,PFDN5,PSMD3,TMPO,EGLN3,CDK9,OSBP,SEC23A,PHB1,CSNK1A1,PIH1D1,PRKCA,RPA2,CFTR,SETD3,ARHGAP1,PSMC4,MARS1,FBXW7,HSCB,EMC1,TTC1,RNF113A,EP300,HSPA8,SIRT7,BMPR1A,DDX39B,RPA3,RIT1,UBE2H,PFDN4,KPNA6,LDHB,CUL3,MYC,CARS1,VIRMA,ATP5F1B,PSMD4,LMBR1L,OPTN,CCNF |
| 1.513e-03 | -6.49 | PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4) | protein interactions | 5303 | 68 | 31 | 19454 | 5460 |
ATP6V1D,RCL1,BICD2,FATE1,RACGAP1,DNAJC8,CSNK2A1,VIRMA,SPTAN1,EIF2B5,UBE2S,PNMA1,RTF2,HEXIM1,RPA2,EZH2,DDX42,SYNRG,SEC22B,CCT5,NDUFA2,HSDL2,RAF1,RAD21,MARS1,PIP4P1,MEPCE,SRPRB,RNF10,UGDH,RPA3 |
| 1.513e-03 | -6.49 | HDHD5 (haloacid dehalogenase like hydrolase domain containing 5) | protein interactions | 27440 | 68 | 31 | 19454 | 5460 |
RPA2,PDHA1,MGARP,NT5C3A,POLDIP2,TNFSF8,RASL10B,FBXW7,EP300,HSPD1,LTA,SLC25A10,RPA3,AMACR,KLK5,POU5F1,SMDT1,UBE2H,TAFAZZIN,MTG2,FAM174A,PMPCA,CDKN3,RAMP3,EGLN3,SSH3,FAHD1,IRF2,AIFM1,CCNF,HDHD5 |
| 1.513e-03 | -6.49 | Tuba3a (tubulin, alpha 3A) | protein interactions | 22144 | 68 | 31 | 19454 | 5460 |
TTC9C,TUBB,TRIM29,TCP1,SLC38A2,HSP90AB1,CCT7,TUBA1B,TYMS,CCT2,ASCC1,PFDN2,NCKIPSD,CCHCR1,PKP4,GTF2I,PFDN1,PRDX4,TMEM209,CTSC,CCT8,UNC50,TUBB4B,HSP90B1,HEXB,FKBP1A,TMEM126A,HEXA,CCT5,SEC22B,TUBA1A |
| 1.513e-03 | -6.49 | SHBG (sex hormone binding globulin) | protein interactions | 6462 | 68 | 31 | 19454 | 5460 |
ACTB,DES,MPDU1,ACTA2,HDHD5,PTGDS,AKR1B1,DSTN,SNRNP70,AK2,FYTTD1,SORD,COL1A2,AP2A1,CTSD,ATP5F1A,SRI,SLC37A4,FLOT1,EIF3E,AZGP1,MT2A,UBE3A,RMND5B,APOBEC3C,APEH,CLDN4,SPMIP6,EEF1A1,SNAPIN,PLP2 |
| 1.513e-03 | -6.49 | ND4 (NADH dehydrogenase subunit 4) | protein interactions | 4538 | 68 | 31 | 19454 | 5460 |
TIMMDC1,YIPF3,GHITM,GPR35,NDUFS3,NDUFS6,CRELD1,ATP5PF,DVL2,NDUFB5,EMP3,NDUFC2,VIPR1,TACR1,SYVN1,DNAJC30,LPAR1,HSCB,IMMP2L,GOLGA7,GPR17,NDUFB7,CCR6,NDUFV2,MRPL18,NKX3-1,NDUFA1,FUT1,PRNP,NDUFAF4,PARL |
| 1.513e-03 | -6.49 | AKAP5 (A-kinase anchoring protein 5) | protein interactions | 9495 | 68 | 31 | 19454 | 5460 |
PRKACB,SUV39H1,GABRB3,RAB11A,RSBN1L,NRP1,PPP3CA,KCNJ2,RHOB,RAB35,DLG4,MDM2,SLC25A12,CAV1,JUN,OTUD6B,TP53,PRKCA,LUC7L3,CDK1,HSPA8,CLK1,DERL1,FOS,DLG1,STX7,FLOT1,H3C1,KRAS,SGMS2,ADRB2 |
| 1.513e-03 | -6.49 | RRAGC (Ras related GTP binding C) | protein interactions | 64121 | 68 | 31 | 19454 | 5460 |
CCR6,SLC38A9,LAMP3,ST13,LAMP2,LAMTOR2,SFN,LAMTOR1,TRAF6,LGALS8,TFE3,ATXN1L,TFEB,MIOS,LGALS3,MITF,LAMTOR3,RRAGA,NUPR1,PSMB7,RPA2,FLCN,HSPA8,SQSTM1,RAB9A,RPA3,WNT2,EIF4E,KRAS,RRAGB,HMGB1 |
| 1.514e-03 | -6.49 | CCDC85B (coiled-coil domain containing 85B) | protein interactions | 11007 | 164 | 64 | 19454 | 5460 |
CRYAB,AGGF1,NDUFA5,ING5,RALYL,CDKN1A,LMO3,FXR2,LDOC1,PSMC1,ZBTB5,FAM50B,SLU7,ATOSB,SAYSD1,GCC1,NIF3L1,BEX3,RBM7,FAM107A,EXOC8,EPS8,HNRNPC,ZNF250,PPP1CC,CEP70,THAP7,FCHSD2,CHCHD3,SCNM1,VPS72,APEX2,MOB4,MAGEA4,EZH2,SKA3,TNNI1,RNF8,BIRC5,DOK5,IKZF5,SOX2,KIAA0408,PSMA1,ZBTB16,ENKD1,COPS4,RIGI,FASTKD5,ZNF821,TFPT,RGS6,RBM41,USP2,SETD5,CENPP,FNDC11,UTP6,PLEKHF2,MEAF6,AKAP17A,TSPYL4,POLR2L,CEBPG |
| 1.514e-03 | -6.49 | MPHOSPH10 (M-phase phosphoprotein 10) | protein interactions | 10199 | 164 | 64 | 19454 | 5460 |
RIT1,H1-1,DCAF4,FTSJ3,ZNF668,RPL7A,MYC,RPL19,ESR2,RPL13A,RPL35,SNRNP40,RPS9,FGFBP1,PRKRA,RPL37A,CSNK2B,RPS3,RPLP0,UTP15,FGF13,H1-5,AATF,RPL4,STAU1,NOP53,NPM3,DGCR8,SIRT7,NLE1,RPS2,SNRNP70,CHCHD1,DDX23,CSNK2A1,WWP2,IFI16,DKC1,LYAR,NOP58,RPS16,RPS10,PWP2,SRSF1,KRR1,RPL8,SRP14,RHOBTB1,SART3,RPS7,E2F4,RPSA,IMP3,RPL17,UTP25,RIGI,IMP4,KRAS,H1-6,RPS24,RPL3,RPL23A,FGF3,RPL31 |
| 1.514e-03 | -6.49 | I-SMAD binding | molecular function | GO:0070411 | 16 | 11 | 18094 | 5411 |
SMAD3,CTNNB1,ACVR1B,SMAD5,SMAD4,FKBP1A,SMURF1,TGFB1I1,SMAD9,SMAD1,SMAD2 |
| 1.516e-03 | -6.49 | ZC3H14 (zinc finger CCCH-type containing 14) | protein interactions | 79882 | 161 | 63 | 19454 | 5460 |
NUP50,DDIT3,SIRT7,NKAPD1,RPA3,DDX39B,SNRPA,AATF,SAP18,HMGB1,FBXW7,STAU1,RALYL,TPT1,SF3A1,PABPC5,ATG16L1,ZCCHC17,RPA2,GSK3A,UBE2S,EIF4A3,CPSF1,ESR2,VIRMA,APEX1,DYNLT3,SNRPB,TYW3,CUL3,HNRNPC,CSK,MYC,MAPRE1,ELAVL2,LMNB1,CHTOP,SRSF7,SOS2,ZC3H11A,ARGLU1,SNIP1,SSRP1,SRSF4,NUP42,THRAP3,CAMKV,G3BP1,DDX39A,CDK4,PDHA1,EZH2,RP9,GLE1,THOC2,THOC1,TOP1,NKAP,SNRPA1,ZNF207,YWHAH,IFI16,SNRNP70 |
| 1.517e-03 | -6.49 | JAGN1 (jagunal homolog 1) | protein interactions | 84522 | 155 | 61 | 19454 | 5460 |
OTULINL,SEC22B,EHHADH,GOSR2,BET1,FDFT1,RPA2,VAPB,LMNA,TIMM23,USE1,TMEM243,STOML3,JAGN1,RPA3,STX7,CLEC12B,VAMP5,FIS1,TMEM100,TMEM106C,CGRRF1,RETREG3,SEC61A1,CYBC1,PLP1,SLC23A2,LMBR1L,CDIPT,VDAC2,FAM177A1,SCAMP2,ELOVL4,TECR,F11R,CCDC47,TMEM14B,RPN1,VAMP2,EDA2R,ERG28,STX8,SMIM19,CLEC7A,SACM1L,FKBP8,DNAJC30,GPR37L1,COPS5,TMEM199,RAB5C,PDZK1IP1,STX1A,FCGR1A,FXYD6,STX5,COX20,SSMEM1,TMEM237,VTI1B,FNDC9 |
| 1.517e-03 | -6.49 | PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta) | protein interactions | 55844 | 155 | 61 | 19454 | 5460 |
BAG2,CCT8,TFPT,PRELP,SERTAD1,TULP3,PPP2R1A,JUN,CCT5,SUPT5H,ZNF263,AAMP,PPP4C,RPS11,PPME1,DMAP1,SKA3,PRR3,PLEKHO2,PPP2CB,GYS1,CCT7,TCP1,CCAR2,TRIM35,HDAC6,CLEC18A,PPP2R5A,PTPN5,FOXC2,AGR2,SHC1,SKIC8,HDAC5,VIP,SERTAD2,WNT7A,DUSP9,FOXD3,LYG2,PPP2R2C,CFTR,FBXO42,SYK,IER2,GTF2IRD1,SNAI2,FOXS1,WNT10B,DUSP10,TCEAL1,DAPK1,TTC33,GSTK1,GRB10,CDKN3,RBM7,CSGALNACT1,COP1,PTTG1,CCT2 |
| 1.519e-03 | -6.49 | S100A6 (S100 calcium binding protein A6) | protein interactions | 6277 | 225 | 84 | 19454 | 5460 |
STX18,PRPSAP1,UCP2,VPS26B,TRIM11,SKA1,S100B,KATNAL1,SIKE1,ZNF821,CDCA7L,RIGI,IL12A,IL13,TNF,UFM1,H3C1,CD2BP2,SPC24,TBK1,TP53,PSMC3,SSBP3,GLE1,EZH2,PPID,NME1,CHMP4C,IL10,SEC23A,HEBP1,RPRD1A,IL3,FOLR1,CACYBP,MDM2,CSF2,SPPL3,PPFIBP1,HDAC6,GAPDH,EXOC1,UTP6,VPS26A,IL21,IFNB1,AGR2,SHC1,FKBP4,MIS12,SQSTM1,STK26,PEBP1,DPH6,PTRHD1,MBD3,UGP2,UFL1,IL5,GPC1,TOM1L2,INTS6L,GH1,IL22,LEP,KLC2,STAMBP,CDR2,EPO,PRL,MANBAL,DTYMK,MOB4,STUB1,S100A6,MYC,DSN1,FMC1,TM9SF4,AP3S2,IL2,IL15,STK24,PPTC7 |
| 1.520e-03 | -6.49 | T cell receptor signaling pathway | KEGG pathways | hsa04660 | 102 | 50 | 7161 | 2463 |
PIK3CA,TNF,SOS2,CD28,PIK3R3,ICOS,GRAP2,AKT2,JUN,ITK,CDK4,PAK5,CBL,IKBKB,PDCD1,VAV2,NFKBIB,IL4,AKT1,PIK3R2,CDC42,KRAS,PIK3R1,DLG1,LCP2,BCL10,CD4,IL10,NFKB1,AKT3,PPP3CA,PAK6,MAP2K1,MAP3K14,CD3G,CD40LG,PRKCQ,CD247,RAF1,NCK1,PPP3R2,IL2,HRAS,NFKBIA,PAK2,CTLA4,IL5,IFNG,FOS,CSF2 |
| 1.520e-03 | -6.49 | T cell receptor signaling pathway | KEGG pathways | ko04660 | 102 | 50 | 7161 | 2463 |
CDC42,PIK3R2,AKT1,IL4,PIK3R1,KRAS,IKBKB,NFKBIB,VAV2,PDCD1,GRAP2,PAK5,CBL,ITK,CDK4,AKT2,JUN,CD28,TNF,SOS2,PIK3CA,ICOS,PIK3R3,IFNG,CSF2,FOS,NCK1,RAF1,PRKCQ,CD247,MAP3K14,CD40LG,CD3G,IL5,CTLA4,NFKBIA,PAK2,IL2,HRAS,PPP3R2,PPP3CA,AKT3,NFKB1,MAP2K1,PAK6,CD4,BCL10,DLG1,LCP2,IL10 |
| 1.525e-03 | -6.49 | MEF2D (myocyte enhancer factor 2D) | protein interactions | 4209 | 82 | 36 | 19454 | 5460 |
NUP35,THOC1,CDK6,PRMT5,LHX2,SP1,AR,MEF2B,YWHAH,YWHAG,XPO1,FBXO7,COPS5,IRF4,AKT1,MOV10,AUH,TAX1BP3,HNF1B,MEF2A,TRIM37,ASF1A,HDAC3,EP300,BAG2,HSPA8,HDAC5,PML,MEF2C,HIRA,PAX9,RBPJ,KLF3,WRAP53,SOX2,JUN |
| 1.525e-03 | -6.49 | LIMK2 (LIM domain kinase 2) | protein interactions | 3985 | 82 | 36 | 19454 | 5460 |
LMNA,HSP90B1,CDK4,CNP,EEF2,SLC31A1,FKBP8,ATP5MK,ATP5F1E,HSPA8,RUVBL2,TTC1,HADHA,SQSTM1,BAG2,PSMD14,FKBP4,ATP1A1,HAX1,HSP90AA1,H1-1,CALU,HSPB1,SERPINH1,MYC,SLC25A1,CUL3,FBXO7,CFL1,IQSEC1,TRIM35,PPP5C,ROCK1,UBB,HSP90AB1,AIP |
| 1.525e-03 | -6.49 | TNNT1 (troponin T1, slow skeletal type) | protein interactions | 7138 | 82 | 36 | 19454 | 5460 |
PSMC5,PNMA1,WDCP,SMURF1,PLEKHF1,HSP90AB1,TRA2A,TPM3,CCDC85B,OSM,ZNF250,ZMYND19,BMPR1B,MORF4L1,SMAD2,ARMC8,UBE2D1,BLOC1S2,DDX5,GID4,FAF1,MAEA,ZC3H15,TNNT2,LDOC1,RNF41,MARS1,FXR2,TRIM63,EEF1G,TULP3,SMAD1,H1-5,TFIP11,TNNI1,NFE2L2 |
| 1.525e-03 | -6.49 | ZCCHC9 (zinc finger CCHC-type containing 9) | protein interactions | 84240 | 82 | 36 | 19454 | 5460 |
RPL26,E4F1,MYC,CUL3,RASSF8,H1-1,MPHOSPH6,RC3H2,FGFBP1,FBXO31,KRR1,SURF2,ESR2,SURF6,RPS16,FAM98A,YES1,SOX2,MAK16,H2AX,RBM38,PABPC5,ZNF574,CYB5B,STOM,EXOSC4,OR1M1,RPS24,EMG1,UTP23,RPL17,CTNNBL1,H1-6,KRAS,NOP53,S100A10 |
| 1.525e-03 | -6.49 | MED30 (mediator complex subunit 30) | protein interactions | 90390 | 82 | 36 | 19454 | 5460 |
MED13L,KRAS,MED11,FBXW7,MED30,FBXL19,RPAP2,CARTPT,ATG16L1,E2F4,MED9,POLR2C,POLR2G,MTA2,POLR2D,MED31,BIRC5,HGS,CDK8,MED23,POLR2F,POLR2L,POLR2B,MED17,POLR2I,H2BC9,INSYN1,MYC,MED22,MED4,BRD3,MED27,MED21,MED10,MED29,STN1 |
| 1.526e-03 | -6.48 | Pancreatic cancer | KEGG pathways | hsa05212 | 64 | 34 | 7161 | 2463 |
SMAD3,RALA,AKT1,ARHGEF6,TP53,PIK3R2,CDC42,KRAS,TGFB2,PIK3R1,CDK6,TGFB3,RB1,CCND1,RAF1,MAPK10,BCL2L1,JAK1,IKBKB,VEGFA,RALB,SMAD4,NFKB1,TGFBR2,AKT3,AKT2,MAP2K1,STAT1,CDK4,PIK3CA,SMAD2,BAD,RAC2,PIK3R3 |
| 1.526e-03 | -6.48 | Renal cell carcinoma | KEGG pathways | hsa05211 | 64 | 34 | 7161 | 2463 |
AKT3,EGLN2,SLC2A1,PAK5,FLCN,AKT2,PAK6,JUN,MAP2K1,PIK3CA,SOS2,CUL2,EGLN3,RAP1B,PIK3R3,PIK3R2,CDC42,ELOC,MET,AKT1,TGFB3,PIK3R1,TGFB2,KRAS,CREBBP,CRKL,PTPN11,VEGFA,RAF1,PAK2,RAP1A,EP300,HRAS,GAB1 |
| 1.526e-03 | -6.48 | Renal cell carcinoma | KEGG pathways | ko05211 | 64 | 34 | 7161 | 2463 |
MAP2K1,PAK6,AKT2,JUN,FLCN,PAK5,SLC2A1,EGLN2,AKT3,PIK3R3,RAP1B,EGLN3,SOS2,CUL2,PIK3CA,KRAS,PIK3R1,TGFB3,TGFB2,AKT1,MET,ELOC,PIK3R2,CDC42,HRAS,GAB1,EP300,RAP1A,PAK2,RAF1,VEGFA,CREBBP,CRKL,PTPN11 |
| 1.526e-03 | -6.48 | Pancreatic cancer | KEGG pathways | ko05212 | 64 | 34 | 7161 | 2463 |
TGFB3,TGFB2,CDK6,PIK3R1,KRAS,ARHGEF6,PIK3R2,CDC42,TP53,SMAD3,RALA,AKT1,RALB,SMAD4,MAPK10,BCL2L1,VEGFA,IKBKB,JAK1,CCND1,RB1,RAF1,CDK4,AKT2,STAT1,MAP2K1,AKT3,NFKB1,TGFBR2,RAC2,PIK3R3,SMAD2,PIK3CA,BAD |
| 1.528e-03 | -6.48 | BBX (BBX high mobility group box domain containing) | protein interactions | 56987 | 102 | 43 | 19454 | 5460 |
RPL31,RPA3,RNF113A,HAPSTR1,RPL4,H3C1,RPS13,RPL28,COIL,CCND1,RPL27A,RPL15,CDC42,CBX3,LMNA,RPA2,MACROH2A2,RPLP0,RPL26L1,ZNF330,TRIM44,PTEN,PRR3,FGFBP1,SHPRH,RPL13A,RBBP4,TRIM54,RPS16,RPL22,APEX1,SURF6,ESR2,VIRMA,KLF9,ZCCHC10,RAB5C,MYC,ANAPC15,SNRNP70,MECP2,BRD3,HSP90AA1 |
| 1.528e-03 | -6.48 | PEG10 (paternally expressed 10) | protein interactions | 23089 | 102 | 43 | 19454 | 5460 |
MAP1B,ABCE1,TOLLIP,TGFBR2,ACVR1B,IMMP2L,RAF1,ACVR1,RNF181,MOB3C,COMT,TSG101,CDK6,VPS26C,ATXN10,TMPO,BMPR1B,IFI16,IRF4,SIAH2,SMCHD1,POU5F1,DNAJC7,SNRPA,BMPR1A,PXMP2,LDOC1,RBFOX2,LNX2,CCNF,PSPC1,SMAP2,SNX12,TAX1BP1,ACTB,SIAH1,PRRC2A,MAD2L2,VIRMA,CUL3,HMGCS1,NONO,UBE2H |
| 1.528e-03 | -6.48 | NFYA (nuclear transcription factor Y subunit alpha) | protein interactions | 4800 | 102 | 43 | 19454 | 5460 |
XRCC5,EP300,APPBP2,TRIM5,LASP1,EIF4EBP2,NFYB,TP53,UBL5,IRGQ,CDKN1A,CCNA2,ELF1,XBP1,ACTN4,JUN,SMNDC1,UAP1,CDK1,JUP,E2F6,SRSF1,CREB1,ZHX3,TES,EIF2S2,GTF2A1,ZHX1,PHAX,TOP1,TAF11,CREBBP,NFYA,HMGA1,MOV10,CTNNB1,CSNK2A1,HMGCS1,BRCA1,TLR9,TOPBP1,SP1,SERPINB1 |
| 1.530e-03 | -6.48 | WDR91 (WD repeat domain 91) | protein interactions | 29062 | 31 | 17 | 19454 | 5460 |
SDCBP,CCT2,BECN1,NAPA,DLG3,TP53,CUL3,CDC42,XPO1,HUWE1,PRNP,APEX1,SYNCRIP,STX8,CCNF,RAB9A,DNAL4 |
| 1.530e-03 | -6.48 | FUNDC1 (FUN14 domain containing 1) | protein interactions | 139341 | 31 | 17 | 19454 | 5460 |
SQSTM1,AKAP1,MAP1LC3A,HSPA8,YES1,SNX1,FUNDC2,SLC25A46,EHHADH,MARCHF5,TUFM,GABARAPL2,GABARAPL1,MAP1LC3B,CTBP1,RPS23,SH3GLB1 |
| 1.530e-03 | -6.48 | Psmd6 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 6) | protein interactions | 66413 | 31 | 17 | 19454 | 5460 |
PSMC5,TXNL1,UBE3A,PSMC1,PSMD12,PSMD4,ADRM1,PRDX3,PSMD1,PAAF1,USP14,PSMD3,PSMC4,PSMC3,PSMD14,PSMD7,PSMD10 |
| 1.530e-03 | -6.48 | CREBZF (CREB/ATF bZIP transcription factor) | protein interactions | 58487 | 31 | 17 | 19454 | 5460 |
NFE2L1,XBP1,CREBZF,TTC23,ATF4,TP53,MOV10,RSPH1,NFE2L2,TIAM1,FAS,VIRMA,APEX1,RIGI,BTG3,BACH1,CTNNBL1 |
| 1.530e-03 | -6.48 | KCNIP3 (potassium voltage-gated channel interacting protein 3) | protein interactions | 30818 | 31 | 17 | 19454 | 5460 |
IGF1R,MAVS,UBE2I,SOD3,OCIAD2,PSEN2,KCND2,CREB1,GOLGA7,PSEN1,CDSN,HNRNPL,KCNIP3,IL6ST,KHDC4,PPP3CA,CTBP1 |
| 1.530e-03 | -6.48 | SH3BP5L (SH3 binding domain protein 5 like) | protein interactions | 80851 | 31 | 17 | 19454 | 5460 |
EMC2,THG1L,TNKS,PPP1R12A,TNKS2,RAB11B,RAB14,YWHAG,YWHAH,TOP3B,RAB11A,HEXIM1,WTAP,YWHAB,YWHAZ,FBXW11,RNF146 |
| 1.534e-03 | -6.48 | mononuclear cell proliferation | biological process | GO:0032943 | 134 | 56 | 18204 | 5365 |
LMBR1L,TP53,IL10,IL12B,IDO1,AZI2,BAX,GPAM,CCND3,SELENOK,IFNA10,PRDX2,SASH3,LILRB1,CD40,HSPD1,BCL6,FOXP3,IFNA13,TLR4,CD40LG,PELI1,PIK3CG,TNFSF18,CD151,TICAM1,IL15,IFNB1,BCL2L1,IL2RA,GAPT,RC3H2,NCSTN,CD28,IL23A,FOSL2,FKBP1B,IL7,MEF2C,EMP2,PSMB10,IL20RB,GJA1,IFNK,CD38,HELLS,ALKBH5,NDFIP1,PRKCQ,EFNB1,IL2,LIPA,MSN,DLG1,TBK1,IFNA2 |
| 1.544e-03 | -6.47 | cell-cell signaling | biological process | GO:0007267 | 822 | 281 | 18204 | 5365 |
RIMS3,GLRA1,KPNA1,HCRT,GNRH1,CXCL9,EFNA3,FCHSD2,ACVR1C,NPBWR1,CCL5,GNAQ,SNCB,CCL17,LY6H,SLC6A2,CREB1,SFRP1,CHRM4,SLITRK5,IL6,HTR2A,CPLX3,GRIK1,TMED1,HTR1F,VDAC1,HNF1B,CCL3,PDLIM4,OPRM1,TNFSF8,CDK5R1,CXCL14,SLC1A3,FGF12,SNAP25,CHRM5,GAL3ST4,GRM1,GRAP2,SNAP29,HTR1A,CCL27,ACHE,GJA10,FGFBP2,MEF2C,DRP2,INSYN1,SYN3,FKBP1B,SLC32A1,ZYX,SNAPIN,RAB1A,SMAD2,SH2D1A,TNFRSF1B,PLCB1,GABRB2,ILDR1,RGS10,INHA,INSYN2A,IFNA2,FGFBP1,GJC1,PSEN1,GRIA2,CBLN2,ENPEP,SYT4,CCDC186,HRH2,CAMK2G,NSG1,SLC6A3,RIMS4,KCNMB1,CCL24,CXCL11,GJB2,LTB,SLC1A1,CTNNB1,FGF10,SLC1A2,GJB1,GABRG2,NPR2,AKT1,KCND2,PKP4,IL1B,SELENOM,PPP3CA,WNT7A,NPY,SLC6A1,TNFSF18,CCL20,GREM1,DRD3,SEMA5A,GABARAP,GAD2,RIT2,TMOD2,NRP1,CHRM1,USP14,GRAP,STXBP1,PTEN,GRID1,CD34,CRHR1,LTA,GSK3A,KCNIP2,PRKCE,CPLX2,CCR1,PRKCB,CCR5,TNR,GNAI2,INSYN2B,CYB5R4,CPE,GRIA1,CCL21,UTS2,GHRL,AR,RIC3,CARTPT,RAB3A,CNR1,CRKL,DLG1,DLG3,IL2,CBLN1,NAPA,EFNB1,HTR5A,PLCL1,NLGN1,PPFIA3,CACNB2,SDCBP,PAFAH1B1,TNFSF10,TAC1,PNOC,GABRA1,CNP,MPZ,SYT2,SCN1B,TNFAIP6,ADRA1A,ADORA1,DAG1,STAC3,LARGE1,TSHR,GABBR1,EXT1,FGFR1,COMT,SST,IL18,ATF4,THY1,PMP22,FASLG,DLG4,LEP,HOMER1,CCL8,MECP2,GABRA2,IL15,TPBG,IL7,EZH2,IL3,CHRNB2,CHRNA7,ADGRG1,ESR2,CPLX1,GPNMB,DNAJC5,PGR,SNCG,NQO1,PCDHB13,OPRK1,SV2B,LIN7C,CXCL13,FZD4,NIBAN2,CLSTN3,ANGPTL2,NTRK2,SCN3B,RAF1,CACNB3,CX3CL1,XCL1,PPT1,FGF3,FGF17,LHB,CLTRN,CRHBP,WNT2,HRH3,DBH,ASIC1,RAP1A,CX3CR1,RAB11B,CDK5,KLF10,STX1A,CCL23,FGF7,GABRB3,HILPDA,SYK,FGF16,GNB1,PLG,STX11,CHRDL1,SELENOT,IL1RAP,S100A8,LIN7B,GLRA2,GPR176,VAMP2,SYPL1,CXCL10,NPPC,NUDT3,PLP1,CGAS,GNA11,NPY5R,FGF13,CCL18,ASIC2,KCNJ8,GUCY1B1,DRD1,CACNB4,SLC16A10,CHRM3,NLGN2,KCNJ3,SLC12A2,GLRB,SNAP23,GJA1,SCN2B,PDYN,LYNX1,NPTX1,VIP,GRM2,PTHLH,SLC29A1,VPS54,RNF10 |
| 1.549e-03 | -6.47 | S100A9 (S100 calcium binding protein A9) | protein interactions | 6280 | 253 | 93 | 19454 | 5460 |
TUBB,MATR3,ILK,ARHGAP19,CUL2,MYC,ASB3,SAP18,RNF11,RNF5,TRA2B,NUBP2,HSPA8,DDX39B,PSRC1,PPARG,PSMB7,NUDT3,DHX15,SRSF10,OCRL,S100A8,HNRNPD,AGR2,CSTA,ZNF207,TRA2A,IFI16,SSRP1,RAD21,CPLX1,TRIM37,G3BP1,SRSF7,EWSR1,TOP2B,S100B,APTX,CCR1,CHMP4C,PPP2R1A,TUBA1A,NCSTN,B3GNT2,TPBG,VIRMA,DEK,GABPA,PTEN,CALML5,EIF4A3,SF3B6,UBE2H,STK11,SPOP,ARHGAP21,SMARCA5,H2AC13,NF2,SQSTM1,LUC7L3,RPL26L1,STX17,ZNF326,PAK5,CFTR,ST7,FBXL19,CDC42,EIF2B5,TOP1,MARCHF4,GNPAT,DSTN,AIFM1,USP15,AGPAT1,UPK1A,SHC1,HDAC6,COPS5,EDEM1,ERCC3,THRAP3,TTC4,PSMA5,EGFL8,SNIP1,RNF8,SERPINA1,TOPORS,SURF4,CD2BP2 |
| 1.550e-03 | -6.47 | adenoma-nodule-goitre | COSMIC cancer mutations | adenoma-nodule-goitre | 64 | 30 | 16828 | 4835 |
PIK3CA,SMARCB1,EZH2,CTNNB1,RB1,TRIM24,GNA11,TSHR,AKT1,PTPN11,IDH2,GNAQ,STK11,MAP2K1,HRAS,TRIM27,FGFR1,TERT,PTEN,TPM3,KIT,MET,TP53,TFG,JAK2,FBXW7,GOLGA5,SMAD4,KRAS,IDH1 |
| 1.554e-03 | -6.47 | Cell Cycle | REACTOME pathways | R-HSA-1640170 | 621 | 229 | 10285 | 3229 |
NUP50,PSMB1,RAB1A,CDC20,RAB1B,CSNK2B,CDC16,SKA1,TUBG1,CDK4,PSMC4,PSMB11,RUVBL2,PSMA4,MCM4,DCTN3,H2BC11,BUB3,RNF8,PSMA2,MCM6,PSMB6,PSME1,CDK7,CDK1,H2BC12,WRAP53,SYCE3,RB1,PSMD14,NEK7,PPP2R1A,UBB,PRKCB,NUP37,PSMD12,RUVBL1,ANAPC16,AKT2,CENPP,H2AJ,YWHAG,FEN1,H2AX,CDK6,XPO1,ANAPC15,RPA3,MAX,NUP153,PSMB9,CSNK2A1,DYNLL1,H2AC14,OPTN,RAB2A,TYMS,RFC4,NEK9,H2BC9,NDE1,POLD4,HSP90AB1,BIRC5,NEK2,E2F4,H2BC14,OIP5,GINS4,CCND1,PSMD10,CSNK1E,MNAT1,RAD21,POLE3,PPP1CB,YWHAH,VRK1,PCBP4,MDC1,PPP1R12A,LMNA,NCAPG2,MLH3,B9D2,PSMC1,COP1,NDC80,KIF2A,CDC7,HAUS2,PPP2CB,HSP90AA1,MAD2L1,MCPH1,SUMO1,AKT1,TUBB,PSMD1,PSMB2,NUP42,CDC23,RAD1,ORC6,CENPL,CCND3,TUBB4B,H2AC4,NBN,DKC1,MIR484,NUP62,PSMA1,PSMD4,MCM3,H3C1,PSMB7,PSMD3,TEX12,ORC5,CDKN1B,CDKN2D,RMI1,PSMA3,PSMB5,PSMB10,SFN,PSMC5,SPC24,H2BC17,CENPW,BANF1,RPA2,TMPO,POLD2,FBXW11,SKP1,DSN1,FBXL7,PSMD7,SMC4,PRKCA,CDC26,H2AZ2,CDKN1A,FKBPL,H2AC7,GINS3,POLA2,CCNB1,H2AZ1,MYC,POLE4,DYRK1A,ARPP19,UBE2V2,NUP107,MYBL2,MAPRE1,RBBP4,ANAPC2,PSMD6,RFC5,UBE2D1,PSME2,CENPM,RFC3,FZR1,CDKN2C,H2BC1,MND1,SKA2,PCNA,CCNA2,TFDP2,MIS12,NUP35,RBBP7,SMARCA5,RFC2,DYNC1I2,PPP2R5A,CEP70,LEMD3,YWHAB,MDM2,PSMA5,CCNH,RMI2,PSMB3,PPP2R5E,PAFAH1B1,YWHAZ,CETN2,EP300,SEC13,TERT,GMNN,UBA52,TOPBP1,H2AB1,BABAM1,SSNA1,MCM8,UBE2N,TUBA1A,PSMA6,AKT3,PSMB4,NHP2,ANAPC4,PTTG1,GORASP2,NUF2,CEP41,BRCA1,SEM1,ACTR1A,UBE2I,H2AC6,PSMC3,TP53,ANAPC11,CKS1B,LMNB1,RBBP8,PRIM2,RPS27A,PPP1CC |
| 1.556e-03 | -6.47 | CCNT1 (cyclin T1) | protein interactions | 904 | 219 | 82 | 19454 | 5460 |
MYC,OST4,AR,CPSF2,RBM15B,ARHGAP21,MECP2,UBE2H,RCL1,TNFRSF1B,CTTN,CPSF1,TACO1,PSPC1,RPS9,GTF2F1,SF3B4,HEXIM2,SIAH1,ESR2,VIRMA,OTUD6A,PPP1R10,PAFAH1B1,UBA52,RPS14,CDK1,RPA2,TOX4,MACROH2A2,HEXIM1,DYRK2,NUFIP2,OXSR1,MFAP1,PRPF4,PML,RPA3,TRIM22,DDX5,WWP2,RPL6,TAF7,SIAH2,PPIL4,HNRNPA1,TIAM1,RPL24,SNRNP70,HSPB1,RB1,CDK6,WDR82,MYBL2,TOP1,RPS16,SPPL3,FAM98A,EGLN3,CDK9,RPSA,TP53,SUPT5H,COMTD1,MAX,CSNK1E,SOX2,NHERF1,DDX42,TUBB4B,TAF2,GNAI3,SNIP1,MRPS11,FAM76B,FGF12,ASF1A,PRPS1,MEPCE,UBE2A,RPS13,RPS27A |
| 1.563e-03 | -6.46 | endothelium development | biological process | GO:0003158 | 106 | 46 | 18204 | 5365 |
FSTL1,EDF1,EDNRA,NRP1,PDE2A,RAB1A,BMPR2,CD34,RAP1B,F11R,MET,CD2AP,NDP,ACVR1,MYD88,FOXC2,CLDN1,FZD4,CLDN3,LIPA,MSN,CSNK2B,MIR21,TMEM100,PDCD10,GSTM3,STC1,RBPJ,ICAM1,CLIC4,CCM2,RAP1A,HAPLN2,CTNNB1,GPX1,RAP2B,RAP2C,STARD13,FOXP3,RAB1B,CXCR4,HEY2,SMAD4,RHOB,PROX1,KRIT1 |
| 1.563e-03 | -6.46 | cellular response to ketone | biological process | GO:1901655 | 106 | 46 | 18204 | 5365 |
RWDD1,CFTR,PCK2,CYP1B1,MIR342,VPS54,SP1,MSN,CDK4,AR,PTGER4,JAK2,PAX6,ADCY3,FOS,SMYD3,ELK1,AKR1C2,USP8,SPHK2,ADCY2,PRKCE,EFNA5,MSTN,ACACA,ATP5F1A,GNB1,P2RY4,GNG2,SPP1,KLF9,AIFM1,AKT1,SRC,DDIT4,FBP1,KLF4,ROCK2,PTGFR,IGF1R,CREB1,SFRP1,PTGER2,GJB2,EIF4E,FBXO32 |
| 1.566e-03 | -6.46 | TMEM52B (transmembrane protein 52B) | protein interactions | 120939 | 105 | 44 | 19454 | 5460 |
SLC38A7,TMEM107,BTN2A2,ZDHHC15,OSBP,WDR44,TMEM97,CNIH1,INSIG2,PGAP2,TMEM205,NRM,PIK3CA,TMEM50B,ATP2B4,EHD4,TMEM147,GPR37L1,DNAJC30,TF,TMEM60,NSG1,VAMP5,PIK3R3,PKP4,SLC35B4,CSGALNACT2,RHEB,TMEM100,PLN,VAMP3,PLP1,TAB1,BET1,TRAM1L1,CLDN4,RAB6A,SEC22A,TMUB2,ORMDL1,BMPR1A,JAGN1,TMEM203,PIK3R2 |
| 1.566e-03 | -6.46 | aminoacyltransferase activity | molecular function | GO:0016755 | 493 | 178 | 18094 | 5411 |
TRIM24,RNF181,PCGF3,IRF2BPL,PELI3,PELI1,MDM2,UBA3,IRF2BP1,RNF182,FBXO22,FBXO11,RNF5,TRIM52,FBXL14,MED17,ZNF451,PIAS1,TRAF7,UBE2E2,UBE2F,RNF26,RNF121,TRIM3,RNF139,CUL2,MARCHF5,MED11,SIAH1,WWP2,WSB1,RNF126,RC3H2,WDSUB1,FBXO25,TRIM5,UFL1,FBXL3,ANAPC11,RAG1,KLHL9,RNF115,KCTD10,UBE2A,CBL,TRIM36,VPS18,TRIM26,UBE2D3,NOSIP,LNX2,MED21,ZBED1,MED27,TRIM23,HECTD3,TRIM63,UBE2H,RING1,CDC23,TRIM6,TRAF6,RNF152,BFAR,MARCHF9,MUL1,RNF20,RNF141,QPCTL,TRIM44,UBE2D1,TRIM37,HECTD1,RNF39,TRIM34,TRIM8,CDC42,GID4,MED31,ZNRF1,SHPRH,ATG16L1,HECW1,HERC3,TRIM27,RNF14,STUB1,ANKIB1,TRIM32,TRIM45,FBXO30,TRAF3IP2,RNF122,HERC4,BRAP,GGT7,SIAH2,RNF34,MED10,UBL4A,EGR2,WWP1,AREL1,TRIM21,FBXO9,TNFAIP3,TRIM22,RCHY1,NEURL2,UBE2L3,TRIM68,TRIM54,RNF146,CDK8,SMURF1,RMND5B,RNF41,FBXO44,MARCHF4,CBLL1,RLIM,TRIM35,RNF10,RNF11,BRCA1,CCAR1,BIRC2,RNF208,RNF167,MYLIP,RNF187,NT5C2,MAEA,UBE2W,TRAF2,UBE3A,MARCHF3,FBXO7,RNF144B,RNF128,RNF113A,ATG3,RNF103,PRPF19,PPP1R11,ASB1,UBE2I,TOPORS,FBXO3,UBE2K,COP1,MSL2,RNF40,UBE2G2,TRIM11,TRIM62,UBE2S,CUL3,RNF8,UBE2B,HUWE1,TNFAIP1,TRIM15,PML,RNF133,RNF7,UBR7,UBE2N,ANAPC4,UBE2E3,RBCK1,DTL,TRIM10,MED30,G2E3,SYVN1,UBE2M,RNF148 |
| 1.573e-03 | -6.46 | regulation of cytokine production involved in immune response | biological process | GO:0002718 | 120 | 51 | 18204 | 5365 |
RIGI,TICAM1,TLR7,IFNB1,TNFRSF14,BST2,SPHK2,MAVS,ACP5,B2M,CD36,SEMA7A,LACC1,TLR9,TNFRSF1B,KIT,IL4,MYD88,TRAF6,NLRP3,CCR2,CD81,LILRB4,IFNA2,LITAF,TNF,IL10,XCL1,DDX1,TLR3,TGFB2,IL6,TRAF2,RSAD2,CLEC7A,TRIM6,MIF,IL18,SYK,SASH3,ANGPT1,TGFB3,IL1B,LILRB1,BCL6,BCL10,HTR2A,HFE,FOXP3,TLR4,PYCARD |
| 1.592e-03 | -6.44 | KRT1 (keratin 1) | protein interactions | 3848 | 213 | 80 | 19454 | 5460 |
LGR4,TP53,FBP1,RAF1,RNF8,EZH2,UBE3A,RINT1,SLC25A5,FAF1,SAR1B,IMPA2,MEPCE,TRIM37,TNF,NEDD8,ARL5B,DDRGK1,HNRNPA1,COPS5,HDAC6,DIRAS2,DPP4,MAGOH,CBL,POU5F1,SHC1,TRAF6,CSTA,KRT8,ARL4D,EED,ARL10,PHB1,EFNA3,HMG20A,TLCD4,DCUN1D1,CAND1,CCNA2,CFTR,NUP62,WTAP,PIH1D1,TFIP11,HEXIM1,METTL14,NMRAL1,BAP1,DVL2,INPPL1,DDX39B,FBXL4,ADRB2,PIK3R2,UFL1,BTF3,CUL2,CUL3,SFN,MYC,PRSS1,UBE2H,TRIM23,RC3H2,UBASH3B,ALB,PI3,AP2M1,EIF4A3,RNF208,LORICRIN,ARF1,IRF2,VIRMA,MBL2,PRKCE,TRIM54,KCTD9,NDN |
| 1.594e-03 | -6.44 | DDX19A (DEAD-box helicase 19A) | protein interactions | 55308 | 85 | 37 | 19454 | 5460 |
CDC5L,NUP35,SH3BGRL,SPTAN1,RB1,PHB1,UBE2H,OAT,NIF3L1,SPOP,WDR12,AR,HDAC6,XPO1,RAB11A,MDFI,MYC,SEPHS1,EIF4E,HSCB,NF2,G3BP1,RAB9A,HSD17B10,TRUB1,PABPC1,SFXN1,EXD2,RPA3,NME1,FGFR1,RPA2,CFTR,BET1,TOMM22,SPTBN1,NUP62 |
| 1.594e-03 | -6.44 | AKAP13 (A-kinase anchoring protein 13) | protein interactions | 11214 | 85 | 37 | 19454 | 5460 |
ATG16L1,TOP3B,MAP2K3,PPARA,DDX42,PRKCA,GNAQ,ZYX,RTKN,ROCK2,STAU1,FBXW7,MYC,BAK1,CUL3,SFN,INSYN1,YWHAG,YWHAH,PPP1CC,NME2,AGR2,YWHAZ,FBXW11,RHOB,YWHAB,CCNF,MAP1LC3A,HNRNPL,PRDX2,PRNP,TAX1BP1,EGLN3,UBB,SRPK2,VIRMA,ESR2 |
| 1.596e-03 | -6.44 | CHEK2 (checkpoint kinase 2) | protein interactions | 11200 | 247 | 91 | 19454 | 5460 |
DCLRE1C,TSSK1B,ENO1,SYT2,CSNK2B,PPP2R5E,DAPK3,BUB3,KLK9,SRPK2,ST13,NONO,CDC73,DVL2,TEX264,BAP1,PPM1G,CYP17A1,PML,NBN,SQSTM1,GTF2I,SMC4,AATF,ARHGAP1,PRMT2,KLRD1,RPA2,CNTN2,UBE2M,MRC1,SYNCRIP,EEF1AKMT3,RCHY1,RB1,FZR1,MDM2,MXI1,NFKB1,CSNK2A1,PPM1D,CCL5,PPP1R12A,DHX9,HNRNPK,KPNA2,FARSA,RNF20,MDC1,CDK4,TP53,TLR3,ACTR2,RNF8,LRRC8A,FBXO22,LMO2,HNRNPAB,MCM3,MYO6,LMNB1,BRCA1,FIS1,XRCC5,SPECC1L,FOS,SF3B1,EEF1G,DAAM1,CDKN1A,LMO3,USP39,CTBP1,RPRD1A,POLR2L,RPS10,CCAR2,DIRAS3,UBXN6,PPP2R5A,SIAH2,CDK5RAP3,FKBP4,CDH13,MYO1B,BAALC,FHL3,ASF1A,RUVBL1,TUBA1A,PPP2R1A |
| 1.601e-03 | -6.44 | protein dimerization activity | molecular function | GO:0046983 | 1074 | 365 | 18094 | 5411 |
NECTIN2,PHB1,NUDT5,ASMT,PIK3R1,JUP,QTRT2,FLRT3,POLR1D,XCL1,DROSHA,CD247,H2BC17,ROPN1B,CDSN,MKLN1,MEF2A,TXN,PAXX,IL17F,H2BW1,GSTM2,FZD4,PDLIM4,CHMP1A,NDP,MMAA,BAX,MSTN,MME,HSD17B1,SYNDIG1,ST6GAL1,TAF7,PHETA2,FERD3L,FIBIN,ID4,MVD,RNF40,H2AB1,CACYBP,DCK,GGCT,LRP6,MEF2C,TYMS,DNPH1,RABL3,TRIM21,KIT,TESC,FUT9,RCHY1,MAP3K11,GSTA4,VPS4B,IDH1,NEUROG2,SMCHD1,POLR2C,PNPO,TP53I3,HMGCS1,H2BC9,AIFM1,GADD45A,CAV1,FCER1G,BST2,ERP29,PSMD7,STK26,PRMT5,CISD1,ADORA1,IL12B,MXI1,HSD11B1,HM13,BMPR1A,EXD2,POLE3,SDS,H2AC13,BNIP3L,ZNF862,MAPK4,GREM1,B2M,CENPW,BHLHA9,PAFAH1B1,SRI,TRIM6,ZBTB16,TAF11,CITED1,AKT1,H2AC4,H2AX,CD4,AOX1,TMEM266,SUPT4H1,ZBED1,CAV2,PPP3CA,NFYB,STUB1,GPHA2,MEF2B,PRPS1,CGAS,TRIM34,HSPB6,THAP1,TPD52,ZBED4,SUPT7L,ZHX3,DNTTIP1,SP1,ENO1,S100A6,CLPX,MORC2,TAF9,SLC39A13,MGAT4A,SMAD4,ATP1A2,MXD1,IMPA2,TERT,XPNPEP1,NUDT16,MYC,MSH6,CAMK2G,HSPB8,ACVR1,POLE4,XBP1,LSM6,H2AC1,RAN,F11R,ANO3,RAG1,PHB2,STOM,SHMT1,TUBA1A,HEY2,S100B,SNX1,TCF21,TPPP,TRIM5,SLC25A27,ALG2,MITF,TWIST2,TFRC,SLC51A,VAPB,RUVBL2,H2AZ2,DAPK3,IRF3,PLN,STK4,ADD1,ZHX1,GTF2A1,TIMM10,TLR4,H2AC7,MMUT,MAD2L1,CER1,SLC7A8,SNX2,MCL1,NACC2,TYW5,H2BC11,CCL5,FBXO7,GCA,ODC1,ABCG2,H2AC25,PAFAH1B2,PIK3R2,TLR6,TPD52L1,SLC7A9,ATG7,ATF4,E2F6,YWHAH,ZNF174,FGFR1,GLCE,CRYM,ADRB3,PML,NEUROD2,ADRB1,GHR,PDCD10,RNF8,CEACAM5,TRIM68,ALDH1A3,ID1,MAX,ATP1B1,FOXP2,TRIM22,RALGAPA2,DPY30,GABBR1,TXNRD2,NAE1,ABCB9,H2AZ1,SMAD3,TFEB,CHRNA7,H2AC6,S100A11,DPP4,TYROBP,ACHE,H2BC12,BHLHE40,DDIT3,UGT1A1,GSTM4,RILPL2,GALE,H3C1,ISCU,BAK1,MACROH2A1,TGFB2,VEGFA,HELT,P2RY1,TCOF1,PGRMC1,GRPEL1,RRAGA,HSP90AB1,CRYAB,PDE2A,HEXA,G6PD,NOG,GPRASP3,KARS1,PDSS2,MAP3K21,EXT1,KLHL7,CHMP4C,S100A10,DR1,IL12A,NTRK2,CHRAC1,SUPT3H,DRAP1,IZUMO1,PADI2,JCHAIN,ACTN4,PYCARD,GID8,CIB2,SOS2,UCP2,IKBKB,SPPL3,GLIPR2,IDE,ST3GAL2,CCL11,ST13,STAT1,TRMT112,BOK,SUPT5H,TSG101,GNPTG,NR4A2,GTF2A2,TMIGD1,BANF1,H2BC1,HSP90AA1,ATP1A1,LILRB1,RPE,HSPB1,PRKRA,IL10,ADIPOQ,TPST1,MAP3K12,ADD2,LSM5,TRIM8,MACROH2A2,KCNB1,CRYL1,TRIM37,BUD23,FOXP3,CYP2R1,TAL2,NR0B1,GSTM3,SRM,TP53,E2F4,ZBTB38,NSMCE3,LDB1,ADRA1A,UBA3,NAA60,SSBP1,GOLGA5,TENM3,H2AJ,DGCR8,PAFAH1B3,SH3GLB1,SDCBP,FBXW11,HAND2,JAML,CLTRN,ATF3,TLR9,ACOX1,MMACHC,TFE3,FBLN5,PRMT2,NPC1L1,STARD3NL,TCF23,HPGDS,H2BC14,FXR2,PPP2R1A,NEUROD6,ADRB2,SLC25A14,GRPEL2 |
| 1.602e-03 | -6.44 | DSG4 (desmoglein 4) | protein interactions | 147409 | 108 | 45 | 19454 | 5460 |
CSGALNACT1,BLOC1S5,SYP,ISCA2,SAMHD1,ESR2,POPDC2,B3GALNT1,ANKH,F11R,RAB9B,ELMOD1,LACC1,EIF4B,SKA2,DRD3,KDELR2,USP6NL,DUSP14,FOXP2,FBXL4,TGIF2LX,HERC3,FOS,SMAD9,PTDSS1,ST6GALNAC3,RAB11B,SRSF10,VTI1B,CPLX3,OR51E2,SGIP1,OTULIN,GEMIN7,CAPZA2,PNMA2,FNTB,TFG,MRPS18C,CACUL1,OAZ3,THNSL1,FSTL1,FBXO3 |
| 1.602e-03 | -6.44 | MAP3K21 (mitogen-activated protein kinase kinase kinase 21) | protein interactions | 84451 | 108 | 45 | 19454 | 5460 |
KCTD3,HSP90AB1,DIRAS3,EIF4E2,RAB35,TIAM1,YWHAB,CAMSAP2,DNAJC7,LAMP2,ATG9A,YWHAG,YWHAH,KRAS,SRSF12,MAP3K11,TESK2,EFNB1,PCNA,KIF1C,HPCAL1,VIRMA,STUB1,YWHAZ,DNAJC10,RHOB,BRCA1,LAMTOR1,SLX1A,DNAJB6,HSP90AA1,FAM110B,RAB11A,SFN,HPCA,SLC31A1,STX7,RTKN,DVL2,FAM53C,CLK1,AGAP1,NCALD,INPP5E,SIPA1L1 |
| 1.613e-03 | -6.43 | negative regulation of hormone secretion | biological process | GO:0046888 | 68 | 32 | 18204 | 5365 |
FGF23,NDUFAF2,ACVR1C,UCP2,KCNB1,ADIPOQ,ENY2,NPVF,GNAO1,JAGN1,UCN,CRHBP,FKBP1B,CCN3,CHGA,SFRP1,CRY1,ADORA1,OSM,IL1B,KCNJ11,TSPO,GJA1,GNAZ,PPP3CA,GHRL,INHA,CARTPT,LEP,HADH,OPRK1,PTPN11 |
| 1.613e-03 | -6.43 | protein autoubiquitination | biological process | GO:0051865 | 68 | 32 | 18204 | 5365 |
BFAR,TRIM52,CUL3,STUB1,RNF122,TRIM37,MARCHF5,CBL,BRCA1,UBE2B,TRAF6,RNF187,RNF181,RNF10,RNF8,KLHL24,RNF133,RNF41,TRIM21,TRIM11,RNF146,MDM2,UBE3A,WWP2,TRIM68,TRAF2,RNF11,RAG1,UBE2D3,RNF141,RNF115,RNF208 |
| 1.615e-03 | -6.43 | palmitoyl hydrolase activity | molecular function | GO:0098599 | 14 | 10 | 18094 | 5411 |
DESI1,LYPLA1,LYPLAL1,ABHD17A,ABHD10,LYPLA2,DESI2,PPT1,ABHD13,ABHD12 |
| 1.615e-03 | -6.43 | ANK2 (ankyrin 2) | protein interactions | 287 | 71 | 32 | 19454 | 5460 |
CTNNB1,BTF3,HAX1,TAF9,FTSJ3,CCT2,MAP1LC3A,CCNF,TNIK,PRNP,POPDC2,RAPGEF5,FZR1,GABARAPL2,GABARAPL1,MAP1LC3B,TP53,RAF1,KBTBD4,SPTBN1,SIGMAR1,UBAC2,FGFR1,DNAJB4,ABCE1,ZYX,PALM2AKAP2,FLOT1,GABARAP,L1CAM,GPM6A,KRAS |
| 1.615e-03 | -6.43 | CARMIL1 (capping protein regulator and myosin 1 linker 1) | protein interactions | 55604 | 71 | 32 | 19454 | 5460 |
PARM1,CDC42,CAPZA2,PAK5,PIH1D1,DLG1,LSM14A,PRKCB,HUWE1,KRAS,CAPZA1,RAB11A,SFN,YWHAG,PIANP,YWHAH,RHOB,RHOG,DDX1,SDC4,RAB35,PSME2,RAC2,IL2RA,RHOJ,FBXO22,HNRNPL,SLAIN2,RABIF,VIRMA,STX6,IDE |
| 1.615e-03 | -6.43 | MAPK4 (mitogen-activated protein kinase 4) | protein interactions | 5596 | 71 | 32 | 19454 | 5460 |
ATP1A1,HSP90AA1,SLC7A11,DNAJC10,RPS6KA4,MAPK4,ACOT8,AKT1,CACYBP,ILVBL,POLR2B,TECR,CCT7,HSP90AB1,FZR1,TCP1,SFXN2,STUB1,GAB1,DYRK2,RAD23B,PAK2,MAPKAPK5,CCT5,FASTKD5,AHCYL1,CCND3,FKBP8,HSPA8,INPPL1,SLC25A10,CCT8 |
| 1.620e-03 | -6.43 | CHCHD2 (coiled-coil-helix-coiled-coil-helix domain containing 2) | protein interactions | 51142 | 244 | 90 | 19454 | 5460 |
DNAJC19,CISD1,CHCHD4,CRYBA1,FBXO7,ATP5F1A,IDE,RNASEH1,TRIM54,CHCHD6,PTPMT1,HEXIM1,HAUS2,PAK5,COX6C,SPRYD4,LMNA,GHITM,H2AB1,COQ8B,POLDIP2,ABCC2,NME4,OIP5,RNF34,MAIP1,RBM23,SOD1,PRPF4,NOL12,RPL24,TIAM1,TDRD7,GRSF1,COX5A,ATP5PD,FZR1,PLEKHF2,COQ8A,ALYREF,CXCL14,COQ10B,RAD1,NDUFS3,GLRX5,LBR,FNTB,ATP5PB,TMEM126A,MEPCE,PDE12,THRAP3,EMC2,THG1L,FAF1,KLHL24,ATP5PF,LSM14B,CHTOP,RBM27,TOMM40,FMC1,PMPCA,UBE2V2,PRRC2A,FKBP10,DHRS4,WDR77,CMAS,EMC1,ATP5MK,CBL,RHOG,ETFRF1,DDX50,CLPX,ZNF593,OCRL,ADCK1,RNF144B,MAGED2,YBEY,FAM136A,PDHA1,PTRH2,TRAF2,UTP25,CHCHD2,UQCC2,NDUFA4 |
| 1.622e-03 | -6.42 | Huntington's disease | KEGG pathways | hsa05016 | 187 | 84 | 7161 | 2463 |
UQCR11,NDUFB7,UQCRQ,NDUFA1,CREBBP,CREB3L4,ATP5F1A,NDUFS2,SOD2,COX6A2,ATP5MC1,SP1,PLCB1,POLR2D,PLCB2,POLR2L,COX6B2,AP2S1,UQCRC1,NDUFS8,COX4I2,DNAL1,NDUFB5,GPX1,NDUFA12,NDUFA4,BAX,PPARG,COX7B,POLR2B,SLC25A4,ATP5PD,NDUFS3,SDHC,ATP5PO,DLG4,CREB3,NDUFAB1,VDAC1,IFT57,NDUFB8,NDUFS6,COX8A,DCTN4,NDUFV2,NDUFB6,AP2A1,CYC1,SLC25A5,UQCRH,NDUFB10,EP300,SLC25A31,DNAL4,POLR2C,COX7A1,POLR2F,COX4I1,TP53,AP2M1,NDUFA5,GNAQ,COX6C,CREB1,POLR2G,ATP5F1B,ATP5F1D,COX7B2,COX6B1,SDHB,UQCRC2,PPIF,VDAC2,NDUFC2,COX5A,ATP5PF,SIN3A,NDUFA2,ATP5F1E,ATP5MC3,SOD1,POLR2I,NDUFB4,ATP5PB |
| 1.622e-03 | -6.42 | Huntington's disease | KEGG pathways | ko05016 | 187 | 84 | 7161 | 2463 |
COX7B2,COX6B1,UQCRC2,SDHB,COX5A,NDUFC2,VDAC2,PPIF,SIN3A,ATP5PF,SOD1,ATP5MC3,ATP5F1E,NDUFA2,NDUFB4,ATP5PB,POLR2I,AP2A1,NDUFB6,NDUFV2,DCTN4,SLC25A5,UQCRH,CYC1,EP300,NDUFB10,DNAL4,SLC25A31,POLR2F,COX7A1,POLR2C,NDUFA5,GNAQ,AP2M1,COX4I1,TP53,ATP5F1B,POLR2G,COX6C,CREB1,ATP5F1D,NDUFB5,DNAL1,NDUFA12,NDUFA4,BAX,GPX1,PPARG,COX7B,SLC25A4,POLR2B,ATP5PO,DLG4,CREB3,SDHC,NDUFS3,ATP5PD,IFT57,NDUFAB1,VDAC1,NDUFS6,COX8A,NDUFB8,NDUFB7,UQCR11,CREB3L4,ATP5F1A,CREBBP,UQCRQ,NDUFA1,SP1,COX6A2,SOD2,ATP5MC1,NDUFS2,PLCB1,PLCB2,POLR2D,UQCRC1,AP2S1,COX6B2,POLR2L,NDUFS8,COX4I2 |
| 1.627e-03 | -6.42 | APLNR (apelin receptor) | protein interactions | 187 | 207 | 78 | 19454 | 5460 |
RAB18,FASTKD5,RAB3B,SLC25A23,RAB13,JAK1,APLN,RINT1,SFXN1,ATP2B4,RUSF1,TMEM87A,SLC25A24,KDELR1,METTL15,AGPAT5,SLC29A1,YIPF3,MAP2K3,IPO8,TMEM126A,CCDC47,MSMO1,DERL2,CAND1,ADCK1,ECHDC1,AKR1B1,XPO5,MPDU1,PTPN1,NUS1,TMEM164,PEX3,EXOC2,FAM241B,DEGS1,DOLK,EXOC1,MZT2B,NR2F6,XPO1,SLC25A46,ORC5,LAMP2,TMEM209,CERS6,CMTM6,UFL1,TMEM126B,RAB29,BMPR1A,FDFT1,TTI2,STX17,SIGMAR1,UBAC2,SLC12A2,NEK7,HACD2,SETD3,TOR1AIP2,TIMMDC1,COQ8B,CPT2,SLC25A4,LGALS3,ABHD17A,MGST3,INTS12,CHCHD6,GGCX,VMP1,TAFAZZIN,OGG1,TM9SF4,GJB2,CSK |
| 1.627e-03 | -6.42 | IGFBP3 (insulin like growth factor binding protein 3) | protein interactions | 3486 | 60 | 28 | 19454 | 5460 |
KRAS,MLH3,TF,IGF1,FBXW7,TRIM52,POLA2,BMPR1A,HNRNPA2B1,IGF1R,STK26,CTDSP1,PPARG,KRT7,RAF1,CCND1,PLG,SPPL3,ACTB,KLK3,CAV1,KRT8,STK11,MYC,CTSD,F2,CSNK2A1,NONO |
| 1.627e-03 | -6.42 | TMED8 (transmembrane p24 trafficking protein family member 8) | protein interactions | 283578 | 60 | 28 | 19454 | 5460 |
XPO1,EI24,SMAD2,REEP6,KCNJ10,ADTRP,SEC61B,LAPTM4A,DEFB129,SEC62,FUNDC1,OTULINL,ZDHHC16,TRAM1L1,NDUFA12,AVPR1B,GPR34,TMEM115,LRRTM3,SSR1,TMEM254,MRPS18B,UNC50,DERL1,STX8,KRAS,MRPL41,CMTM6 |
| 1.628e-03 | -6.42 | SIRT6 (sirtuin 6) | protein interactions | 51548 | 622 | 208 | 19454 | 5460 |
RPLP0,CDK1,LMNA,AATF,TMEM209,BRIX1,PIAS1,SMC4,GTF2I,H2BC12,DVL2,KPNA6,ZNF687,CDC16,PTEN,TRIM27,CTTN,STUB1,PELP1,POLR2G,PPP4C,DMAP1,EEF1A1,MAP2K3,CCT5,SMN1,MDC1,MSH6,CTNND1,RNF20,CAMK2G,PAK1IP1,HUWE1,EMC2,RPL23A,NKRF,TCOF1,FAF1,CLP1,SMG9,ESYT1,MPHOSPH10,MOV10,ERCC3,MDM2,POLR2I,TSC22D3,PWP2,RPL12,AIFM1,H2AZ1,SRP14,WDCP,ELF5,ADNP,LARP4B,PPARG,MED23,ACTL6A,G3BP2,RPS5,MCM4,MCM3,RNF40,TM9SF4,RBBP4,DYNLL1,MED17,RPL37A,VPS72,PARP2,SART3,NLRP2,POLR2C,POLR2D,EXOSC3,NUP153,GFPT1,RFC3,SSRP1,RAD21,GTF3C3,MCM6,RBBP7,ZNF592,G3BP1,UBE3A,PPAN,TRIP4,DICER1,NQO1,CDKN1B,MRPS26,UBE2D1,SKIC8,NUP35,KIAA0232,CACYBP,CCAR2,SNX18,RPLP2,MYEF2,RPL8,RPL9,WDR6,HECTD1,LEMD3,ACACA,PARD6A,RPA2,RPRD1B,GTF3C4,GTF2H4,FTSJ1,HDAC3,WDR3,KDM1A,LSM12,HNRNPH2,PSMG4,PML,POLD2,PSMG3,ANAPC4,DNAJC10,ANAPC15,AKT1,VPS39,SMARCA5,SRPK2,DYRK1A,CDC20,MACROH2A1,CSNK2B,CCSER2,RAD1,CBX3,RPAP2,IMP3,RPL17,MNAT1,CAPZA1,KPNA2,IMP4,HNRNPK,H3C1,NUP107,DHX9,RPL3,CLPB,RPL10A,USP15,SMG8,KPNA1,AKAP8L,RPS2,SNRNP70,H2AC4,MED27,GAPDH,EDEM1,DKC1,MIOS,SYNCRIP,NUFIP2,NUP62,EEF1G,STAU1,FXR2,HSPA8,XRCC5,DDX39B,SERPINH1,POLR1B,RBM27,FTSJ3,APEX1,POLR2B,MATR3,PRMT5,RPS23,RPL18,MTA2,EEF2,KIF2A,NUP37,TUBA1A,DHX38,SUPT5H,TRMT1L,UTP25,RUVBL1,HNRNPF,RUVBL2,CCT8,TOP2B,ABCF1,DRG1,CDC23,H2BC17,CTNNB1,DDX50,CCT7,TRMT61A,TCP1,S100A8,MAGED2,RPRD1A |
| 1.629e-03 | -6.42 | Signaling by Wnt | REACTOME pathways | R-HSA-195721 | 336 | 131 | 10285 | 3229 |
AP2S1,H2AX,WNT7A,TLE1,AKT2,H2AJ,PARD6A,AP2M1,CSNK1A1,GNG3,XPO1,CDC73,SOX9,H2AC7,H2AZ2,GNGT2,GNB3,PRKCB,RUVBL1,H2AZ1,MYC,SOST,PSMD12,H2AC14,CSNK2A1,H2BC1,GNB4,FZD3,H2BC9,PPP3CA,PSME2,SFRP1,PSMD6,PSMB9,TNKS2,RAC2,PSMA4,H2BC17,PSMB10,PSMB11,PSMC5,PSMB6,PSMA2,PLCB2,TMED5,TNKS,H2BC11,PSMB7,PSMD3,CSNK2B,H3C1,PSMB1,SOX2,PSMA3,PSMB5,PSMC4,WNT2,PSMD14,KLHL12,GNG7,PRKCA,CTBP1,PPP2R1A,UBB,USP8,AGO1,FZD4,PSME1,SKP1,GNG12,GNG2,H2BC12,PSMD7,SMURF1,PPP2CB,GNG11,GNAO1,PSMB2,PSMD1,PSMA6,AKT1,DVL2,H2AB1,FZD6,CUL3,SNX3,PSMC1,CREBBP,CTNNB1,PSMC3,CAV1,H2AC6,PSMA1,RPS27A,RNF146,MIR937,PSMD4,VPS26A,PSMB4,WIF1,SEM1,H2AC4,LRP6,GNG5,PLCB1,PSMA5,GNG10,PPP2R5E,GNG13,AP2A1,H2BC14,PSMB3,DKK1,WNT10B,CTNNBIP1,PDE6A,PPP2R5A,TERT,BCL9,DAAM1,GNB1,UBA52,TNRC6C,LGR4,PSMD10,HECW1,CSNK1E,MOV10,YWHAZ,EP300,SOX3 |
| 1.632e-03 | -6.42 | urinary_tract-bladder-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-squamous_cell_carcinoma | 33 | 18 | 16828 | 4835 |
GNAQ,MAP2K1,KRAS,HRAS,AKT3,FGFR1,PIK3CA,CDK4,TERT,AKT2,CTNNB1,MET,KIT,TP53,AKT1,PTPN11,JAK2,FBXW7 |
| 1.632e-03 | -6.42 | desmoplastic_small_round_cell_tumour | COSMIC cancer mutations | desmoplastic_small_round_cell_tumour | 33 | 18 | 16828 | 4835 |
PIK3R1,IDH1,HRAS,KRAS,EWSR1,MAP2K1,SS18,GNAQ,IDH2,JAK2,PTPN11,ETV6,AKT1,KIT,MET,CTNNB1,PIK3CA,FGFR1 |
| 1.632e-03 | -6.42 | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoplastic_small_round_cell_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoplastic_small_round_cell_tumour | 33 | 18 | 16828 | 4835 |
IDH2,PTPN11,ETV6,JAK2,AKT1,KIT,MET,CTNNB1,PIK3CA,FGFR1,PIK3R1,IDH1,HRAS,KRAS,EWSR1,MAP2K1,SS18,GNAQ |
| 1.632e-03 | -6.42 | small_intestine-duodenum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-duodenum-carcinoma-adenocarcinoma | 33 | 18 | 16828 | 4835 |
SMAD4,SF3B1,STK11,KRAS,HRAS,NTRK3,SMARCB1,PIK3CA,FGFR1,FBXW7,CDKN2C,AKT1,PTPN11,JAK2,TP53,CTNNB1,KIT,MET |
| 1.634e-03 | -6.42 | BOLA2 (bolA family member 2) | protein interactions | 552900 | 111 | 46 | 19454 | 5460 |
ZNF177,UBE2H,MOBP,COP1,CUL3,CUL2,MYC,DNAJC5,NTAQ1,VIRMA,DLST,EIF4A3,FGFR1,MAP2K1,CDK1,PIH1D1,HEXIM1,UBE2M,CDK7,STAU1,ARHGEF39,UFL1,PEBP1,EP300,RNF113A,BIRC2,CRBN,SLITRK5,MAGOH,ZNF688,WWP2,NDC80,DDRGK1,YWHAH,TXNRD3,ZNF511,OCRL,FZR1,NUF2,TSPYL4,CGGBP1,MTA2,SPC24,ZNF581,VDAC1,MEPCE |
| 1.634e-03 | -6.42 | VARS2 (valyl-tRNA synthetase 2, mitochondrial) | protein interactions | 57176 | 111 | 46 | 19454 | 5460 |
RMND1,GATD3,LDLR,PHB1,COX4I1,SSBP1,AIFM1,CD274,MRPS26,CHCHD1,ATG7,GRSF1,MTRF1,IMMP2L,FASTKD5,KRAS,COX8A,HINT2,SFXN1,HSPD1,SNIP1,UCK2,PDHA1,PIK3CA,METTL15,MRPL11,RAF1,PARL,APEX1,CCDC90B,MTG1,TACO1,RIT1,HTRA2,TUFM,PMPCA,AUH,MTG2,CRYZ,HSCB,GFM1,AMACR,EXD2,RPA3,NGRN,MTRES1 |
| 1.635e-03 | -6.42 | Resolution of AP sites via the multiple-nucleotide patch replacement pathway | REACTOME pathways | R-HSA-110373 | 24 | 15 | 10285 | 3229 |
POLB,PCNA,APEX1,POLE3,FEN1,RPA2,PARP2,RFC4,POLD2,RFC5,POLD4,RFC2,RPA3,RFC3,POLE4 |
| 1.635e-03 | -6.42 | amide biosynthetic process | biological process | GO:0043604 | 140 | 58 | 18204 | 5365 |
HACD2,CERS2,MMUT,ST6GALNAC3,OSBP,PPT1,CERS6,ELOVL3,ACSL4,SGMS1,CHAC2,ASMT,FA2H,DEGS1,SLC25A1,SLC1A1,NANP,SLC1A2,AANAT,ACSS2,DLAT,GGTA1,ORMDL3,GCLC,GAL3ST1,PDHB,SPTSSB,B3GALT1,ELOVL6,HACD1,B4GALT4,ELOVL7,CLN8,UGCG,GGT7,ST3GAL1,SMPD2,ACACA,ELOVL1,B3GALT2,ARG2,SPTSSA,TECR,B4GALT3,MGST2,ORMDL1,SGMS2,ST3GAL5,PDHA1,AGK,ACAT1,CYP4F22,ST3GAL2,B4GALT6,B3GALT4,ELOVL4,TLCD3B,ST8SIA4 |
| 1.639e-03 | -6.41 | mucinous | COSMIC cancer mutations | mucinous | 38 | 20 | 16828 | 4835 |
SRSF2,TP53,BRCA1,CTNNB1,KIT,MET,FBXW7,PPP2R1A,IDH2,AKT1,JAK2,PIK3CA,FGFR1,DICER1,PTEN,KRAS,IDH1,PIK3R1,SMAD4,SF3B1 |
| 1.640e-03 | -6.41 | Mitotic G2-G2/M phases | REACTOME pathways | R-HSA-453274 | 184 | 77 | 10285 | 3229 |
PSMD6,PSMB4,PSME2,TUBB4B,PSMB9,ACTR1A,MIR484,CEP41,SEM1,PSMA1,DYNLL1,PSMC3,TP53,PSMD4,CCNA2,OPTN,RPS27A,FKBPL,CDKN1A,SSNA1,PSMD12,CCNB1,PSMC1,TUBA1A,PPP2CB,YWHAG,HAUS2,MYBL2,HSP90AA1,PSMA6,XPO1,PSMB2,PSMD1,RBBP4,MAPRE1,TUBB,SKP1,CDK7,CDK1,PSME1,CSNK1E,PSMD10,FBXL7,CETN2,PSMD7,EP300,PAFAH1B1,MNAT1,PSMD14,PPP1CB,UBB,PPP2R1A,PPP1R12A,UBA52,PSMB1,NDE1,PSMD3,HSP90AB1,PSMB7,TUBG1,PSMC4,DYNC1I2,NEK2,PSMB5,PSMA3,CEP70,PSMB11,PSMC5,PSMB10,CCNH,PSMA5,DCTN3,PSMA4,PSMB3,FBXW11,PSMA2,PSMB6 |
| 1.641e-03 | -6.41 | DBN1 (drebrin 1) | protein interactions | 1627 | 370 | 130 | 19454 | 5460 |
PPP1CC,CFL1,CFL2,ARHGAP21,CALU,MAPRE1,UBE2H,ABCG2,AP2A1,PTEN,RTRAF,CTTN,CCNF,DYRK1A,HOMER1,SH3BGRL,YES1,DAPK1,TMOD3,CDK7,CFTR,CDC42,TPT1,SPTBN1,PRKCA,MEST,TMOD1,RPLP0,HEXIM1,STOM,PICALM,PAK5,RPA2,JUP,ARPC2,MTDH,PML,BAP1,RHOU,RPA3,HSPA5,PIAS1,NF2,HDAC6,BAK1,MOV10,DPP4,STYK1,TMOD2,SNRNP70,H2AC4,RAC2,TES,ACTA2,CAV1,SURF6,CDK9,FCHO2,PRNP,PPP1R18,MAP1LC3B,TP53,FBP1,NUPR1,TAB2,DISC1,CAPZA2,ARPC3,ACTR2,CYBRD1,HAPSTR1,PPP1R12A,RAB1A,PALM2AKAP2,DUSP19,MEPCE,FBXO25,CDK2AP2,CAMK2G,BTF3,RIOK2,MYC,CDKL2,SP1,MYO6,RRAS2,AP2M1,DLST,PPP1R3C,ACTB,TAB1,STAT1,CD59,NUDT3,TIMM13,PPP1CB,PPT1,RAB5A,NMRAL1,SPECC1L,FOS,DDX39B,PACSIN3,STAU1,UBE2D3,MAGOH,ATP6V1A,CORO1C,PHB1,SDC4,HOMER3,STK3,HSP90AB1,EGLN3,ERLIN1,RHOH,KCTD10,SPTAN1,ACTN4,SOX2,SUPT5H,RHOBTB1,RND3,PDHA1,CHMP4C,EZH2,MYO1B,FLOT1,TRIM37,G3BP1 |
| 1.643e-03 | -6.41 | DYNLT1 (dynein light chain Tctex-type 1) | protein interactions | 6993 | 241 | 89 | 19454 | 5460 |
NKAP,MAPRE2,DBT,WDCP,SSBP1,ADD1,DYNC1I1,SLC25A10,PC,SNAP23,BMPR2,PPP4C,ILF2,GNAI3,ESS2,TXN,YES1,DYNLT3,CTTNBP2NL,RPL22,CCNF,GAB1,ARFGAP3,PPIG,MAPRE1,UBE2H,OLFM3,ARHGAP21,NTAQ1,KDM1A,DVL2,BAP1,SOD1,NBN,ARFIP1,RPA2,LMNA,SDCBP,ZCCHC17,PRKCA,HECTD1,ACACA,SYNRG,KLF12,SUMO3,LYAR,DYNC1I2,KLHL7,IQSEC1,BTF3L4,PSMA1,S100A10,ETFA,VDAC1,RAD21,IMMP2L,GNA11,ARGLU1,TUBB4B,ETFB,NUP153,NUDCD3,KIF2A,DYNLL1,LRIF1,GNB1,ERH,ESR2,PHF12,PELO,DYNLRB2,PRMT5,YWHAZ,FTSJ3,NSA2,HTRA2,DNAJB6,CUL3,PCCB,BAG3,FXR2,HSCB,NSFL1C,NUP50,NUFIP2,RRAGA,NUP62,PAFAH1B1,ZC3H14 |
| 1.643e-03 | -6.41 | regulation of protein localization to plasma membrane | biological process | GO:1903076 | 109 | 47 | 18204 | 5365 |
SQSTM1,TMBIM1,CLIP3,AGR2,STX8,PRNP,CDK5,AKT1,VAMP8,STAC3,EPHA2,ZDHHC8,RANGRF,KCNJ11,VPS4A,CSK,MMP14,DPP10,IFNG,TNF,MIR223,PGRMC1,SPTBN1,ACTB,TMEM59,DLG1,AR,PICALM,ATP2C1,ARF6,PID1,RHOG,NGDN,PPP2R5A,PIK3R2,PIK3R1,AP2M1,LYPLA1,VTI1B,PRKCE,RAMP3,CNPY4,STX7,RER1,LGALS3,BCL2L1,ATP2B4 |
| 1.653e-03 | -6.40 | intrinsic apoptotic signaling pathway | biological process | GO:0097193 | 163 | 66 | 18204 | 5365 |
BAX,IER3,BAK1,FLCN,TRAF2,FHIT,SOD2,DDX5,NUPR1,SELENOK,EDA2R,GPX1,CRIP1,TMEM117,EP300,TNF,PDCD10,POLB,DYRK2,BOK,TP53,MAEL,DDIT4,STK11,ATF4,HRAS,PYCARD,IFI6,DDIT3,DNAJC10,AIFM1,EPHA2,TMBIM6,CASP4,PMAIP1,BAD,BCL2L1,CUL2,JAK2,HINT1,CDIP1,BCL2A1,PML,CDKN1A,CIDEB,IVNS1ABP,ZNF622,TOPORS,IFI16,MSH6,SFN,RRN3,ARL6IP5,NBN,RPS27L,TNFRSF1B,HTRA2,PIK3R1,GSKIP,CUL3,STK24,MLLT11,ERO1A,BRCA1,MCL1,CYP1B1 |
| 1.658e-03 | -6.40 | LONGIN | prosite domains | PS50859 | 5 | 5 | 12186 | 3388 |
VAMP7,SEC22B,SEC22A,YKT6,SEC22C |
| 1.658e-03 | -6.40 | HIT_2 | prosite domains | PS51084 | 5 | 5 | 12186 | 3388 |
FHIT,APTX,HINT1,HINT3,HINT2 |
| 1.658e-03 | -6.40 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090092 | 320 | 119 | 18204 | 5365 |
GREM1,SMAD4,CHRDL1,STK11,MIR361,CREBBP,MIR23A,NOG,EMILIN1,MIR98,TGFB3,DKK1,HFE,ACVR1B,CTDSPL2,STUB1,MIR205,MIR9-1,ING1,SPRED2,MSX1,MIR145,CCN3,FGF10,RBBP4,RBPJ,BRMS1L,TGFB2,MIR101-1,SMAD3,SPRED1,RBBP7,TWSG1,SAP30,NOTCH2,EP300,CHST11,UBE2D1,CSNK2B,MIR497,MIR130A,TGFBR2,MIRLET7B,ACVR1,MIR373,MIR20A,MIR214,MIR17,HTRA1,CITED1,GREM2,MIR424,RGMA,GLCE,EID2,SAP30L,ILK,PELO,CAV2,SOSTDC1,JAK2,FKBP1A,FOLR1,CER1,MIR140,PPARA,USP15,SPRY1,MIR885,FAM89B,PBLD,MIR26B,MIR490,UBE2D3,MIR142,SOST,NEO1,MIR302B,SFRP1,FLCN,ZNF451,TNFAIP6,DLX1,TP53,FKBP8,IL17F,PEG10,SDCBP,SFRP4,MIR146A,MIR30B,MIR21,MSX2,PPARG,ELAPOR2,NREP,BRMS1,SMAD2,MIR342,MIR106A,MIR100,LDLRAD4,SMURF1,HSPA5,ING2,CAV3,DKK3,HSP90AB1,MIRLET7G,MIR195,LEMD3,BMPR2,MIR210,BCL9,BMPR1A,TGFB1I1,MIR204,SIN3A,FSTL1 |
| 1.658e-03 | -6.40 | ME2 (malic enzyme 2) | protein interactions | 4200 | 88 | 38 | 19454 | 5460 |
HNRNPL,DYNLL1,GATD3,AIFM1,SSBP1,CCDC90B,COX4I1,MTG1,PHB1,OAT,MRPS26,MTRF1,AUH,MTG2,PMPCA,PYCR2,PYCR1,IFT25,LDHB,PRDX4,IMMP2L,RIGI,HSCB,STAU1,HSPA8,HINT2,GFM1,COX8A,HSPD1,RPA3,SIRT7,IDH3A,EXD2,RPA2,KLF3,PDHA1,WDR77,MRPL11 |
| 1.660e-03 | -6.40 | USP20 (ubiquitin specific peptidase 20) | protein interactions | 10868 | 201 | 76 | 19454 | 5460 |
MDFI,GPRASP2,CTNNB1,FATE1,TPM3,CSTA,TRAF6,AGR2,PSMD7,USP15,SERPINC1,S100A8,WDR82,HSD17B11,RPS16,RPS10,SPTAN1,EEF1A1,H1-3,TRAF2,NUP153,TUBA1A,STIM1,TNNI1,KCNF1,RPL3,ADRB1,CBX7,PSMD12,ENKD1,POLDIP3,RFC3,RFC2,EIF3E,CTSD,RPL7A,MCCD1,ATP5F1A,GPRASP3,TRIM23,RPS5,IRAK1BP1,ZNF343,DIO2,DLST,ALB,SEC61B,TXN,TUBB,PSMD6,ACTB,ATP6AP2,SPTBN1,UBA52,BEND5,MYL12B,OTULINL,SEC62,LMNA,JUP,VAPB,GTF2IRD1,ZNF770,MYL6,RFC4,SQSTM1,DERL1,UCHL3,ATP6V1G2,FBXW7,HAND2,ADRB2,CDSN,TACR3,AZGP1,HSPA5 |
| 1.663e-03 | -6.40 | SMS (spermine synthase) | protein interactions | 6611 | 114 | 47 | 19454 | 5460 |
PTPN1,IGBP1,PRNP,PDIA3,YWHAG,HNRNPA1,PSMD10,PSMD7,AGR2,TSNAX,YWHAB,HSPD1,HNRNPF,CSE1L,ETFA,HNRNPK,PDRG1,TFG,CAPZA1,NAA15,DDX39A,EZH2,PDHA1,NHERF1,CCNF,DLST,CMBL,LDHA,ADRM1,TSN,BCCIP,MCM3,CHORDC1,PIP4K2C,OSGEP,SORD,RPA3,BAP1,MAPKAPK3,HSPA8,UCHL3,ATP6V1C1,PPP1CB,DUSP22,RPA2,LDHAL6B,EIF4B |
| 1.665e-03 | -6.40 | DNA-directed RNA polymerase complex | cellular component | GO:0000428 | 102 | 44 | 19108 | 5553 |
TAF7,CCNH,MCM3,POLR2G,POLA2,ERCC3,POLR1D,GTF2H5,GTF2F2,POLR1B,TAF2,GTF2A2,POLR2I,TCEA1,CDK7,POLR2B,POLR2L,POLR2C,POLR3H,SUPT3H,TAF5L,TAF11,TADA3,GTF2F1,GTF2E2,POLR2F,TAF10,POLR3B,GTF2A1,GTF2H4,MNAT1,POLR2D,CDC73,SKIC8,POLR3F,POLR1H,PRIM2,GTF2H2,ENY2,PAAF1,POLR3GL,GTF2B,TAF9,GTF2E1 |
| 1.667e-03 | -6.40 | SLC25A13 (solute carrier family 25 member 13) | protein interactions | 10165 | 238 | 88 | 19454 | 5460 |
MEPCE,RBCK1,EMC2,SFXN1,MAP1B,FURIN,MGARP,APOO,TP53,SLC25A12,ARF6,COX4I1,COMT,HACD3,AIFM1,POR,TUBG1,EMC4,DPP4,FBXW7,NF2,RNF113A,SYVN1,SIRT7,DVL2,RPA3,GRM2,RPA2,CFTR,UQCRC1,GABRA1,ATG16L1,VIRMA,ALB,PTEN,CCNF,UBE2H,NRP1,TXNIP,RC3H2,FBXO7,RNF148,CSK,SLC25A1,VDAC1,G3BP1,ZC3H7A,PDHA1,EZH2,TUBA1A,B3GNT2,RAF1,TOP3B,COX14,EGLN3,ATP6V1A,BRD9,CORO1C,PHB1,RAB35,HSPB1,IKBKB,DDRGK1,CTNNB1,BABAM1,IFI16,G3BP2,COIL,PHB2,ADRB2,UCHL3,UFL1,EMC1,AKAP1,CSNK1A1,PPT1,ASB8,MAD2L2,ESR2,PARL,FBXO22,DLST,ILK,RHOB,LAMTOR1,BTF3,CUL3,MYC |
| 1.669e-03 | -6.40 | BCL9L (BCL9 like) | protein interactions | 283149 | 44 | 22 | 19454 | 5460 |
LHX2,CDC73,AR,CTNNB1,SSBP4,LDB1,NUP35,SRPK2,VIRMA,ESR2,SNRNP40,SSBP3,PAX9,EZH2,LMO4,EGR2,SOX2,SSBP2,BCL9,EWSR1,DVL2,ORC6 |
| 1.669e-03 | -6.40 | ZBTB25 (zinc finger and BTB domain containing 25) | protein interactions | 7597 | 44 | 22 | 19454 | 5460 |
PNMA5,KXD1,MDFI,TBC1D5,PCBD1,CTNNB1,TRAF2,TRAF6,ELP6,ZBTB25,PML,HCLS1,VMAC,DDIT3,SUMO2,SPPL3,KCTD9,SEPHS1,ZBTB2,HSPA5,HSBP1,COIL |
| 1.669e-03 | -6.40 | Htatsf1 (HIV TAT specific factor 1) | protein interactions | 72459 | 44 | 22 | 19454 | 5460 |
APOBEC3G,MTG1,MRTO4,RPS27L,SNRPA1,RBM17,SUV39H1,RC3H2,TPPP3,SDHC,RPL23A,ERP29,SNRNP48,STAU1,PRDX4,STRBP,UBL5,RPSA,CD2BP2,RPN1,LLPH,SNRPE |
| 1.669e-03 | -6.40 | FDX1 (ferredoxin 1) | protein interactions | 2230 | 44 | 22 | 19454 | 5460 |
RIT1,GLOD4,CYP11B2,ATP5F1A,ACO2,ATP5F1B,GATD3,NUDT9,SSBP1,GSTP1,ARCN1,CAPZA2,IDH2,NDUFAB1,PGM1,CMPK1,FEN1,HSCB,COX8A,PRDX6,BAP1,SOD1 |
| 1.676e-03 | -6.39 | ribonucleotide metabolic process | biological process | GO:0009259 | 393 | 143 | 18204 | 5365 |
ATP1A2,NDUFA2,BPGM,ACAT1,UMPS,DLG1,ACOT8,MVD,SDHB,PTHLH,ATP1B1,TECR,ENTPD4,ATP5PF,PDHA1,TPST1,BAD,NUDT3,DCK,ACACA,ELOVL1,ATP5F1D,ATP5MC1,NDUFB5,GUCY1B1,CACNB4,ADCY2,ELOVL6,UCK1,NUDT9,PDE2A,CLPX,NPPC,SULT1A3,PFKFB2,FKRP,NME2,PDHB,ATP5MK,GTPBP1,NDUFA5,EPHA2,PGAM1,ABHD14B,OLA1,LDHA,NDUFA1,PDE8A,PPAT,NUDT2,ATP5PD,GPAM,NPR2,ATP5F1B,UCKL1,ATP5MG,PPT1,NT5C2,UCP2,PDE1A,UQCC3,NUDT7,NDUFB8,PAPSS2,LIPA,PGK1,ATP5PO,ELOVL4,AK5,NDUFS6,GUK1,NDUFC2,MFN1,OGDHL,RAN,NUDT5,SDHC,PDE9A,ATP5F1E,AK3,FAR2,CMPK1,ACOT6,NDUFS3,NUDT19,NME4,HMGCS1,DCAKD,GAPDH,AK2,ELOVL7,HACD1,ADSS2,HINT1,NDUFB4,ADCY3,ATP6V1A,UPRT,PDE4B,ENO2,GLYAT,UCK2,MPP1,NDUFA12,PDE7A,COX11,SULT1B1,ATP5MC3,NDUFB7,DLAT,ACSS2,HTR2A,ENO1,HSPA8,NDUFS8,NDUFAB1,NME1,PNP,NDUFB10,ATP5F1A,DLST,SLC25A1,NDUFB6,PGM1,NDUFV2,IER3,NDUFS2,SUCLG2,GNAI3,ADK,HACD2,GMPS,NUDT18,MMUT,RAB23,CASK,ELOVL3,DNAJC30,STOML2,ACSL4,FITM2,NUDT4,ATP5PB |
| 1.676e-03 | -6.39 | TPX2 (TPX2 microtubule nucleation factor) | protein interactions | 22974 | 198 | 75 | 19454 | 5460 |
ESR2,PRRC2A,VIRMA,DYRK1A,APEX1,MAD2L1,EZH1,UBE2S,MRPL53,MACROH2A1,BRCA1,RIT1,SERPINH1,PPIG,EPHA2,RAB11A,MYC,DNAJC8,PPP1CC,AR,NKAPD1,RPA3,PPM1G,DDX46,HELLS,EP300,SQSTM1,CHMP1A,RPA2,LMNA,NCOA5,LEMD3,CSNK1G3,SNRNP27,SUMO2,RPL35A,FZR1,CDC5L,EGLN3,CD274,H2AZ1,CDK6,IKBKB,TUBG1,BRD3,CDK12,KPNA1,HMGA1,PIK3R1,GSTM3,SUV39H1,SIAH2,NGDN,TOLLIP,KPNA2,ASF1A,H3C1,G3BP1,ATP1A2,KRAS,POLDIP3,MDC1,ARGLU1,SNIP1,BAG2,SOS2,EWSR1,EZH2,RP9,CBX3,RBPJ,E2F4,RAF1,TBK1,PPIF |
| 1.683e-03 | -6.39 | response to hydrogen peroxide | biological process | GO:0042542 | 98 | 43 | 18204 | 5365 |
NQO1,CYP1B1,HBB,CAPN2,BECN1,FXN,PPIF,SOD1,NFE2L2,TXNIP,STAT1,HP,MAP1LC3A,FKBP1B,EZH2,PCGF2,TOP2B,PPP2CB,CDK1,GLRX2,HSPA8,AIFM1,SRC,STAT6,HDAC6,KLF4,OSER1,RHOB,MDM2,UBE3A,IL6,TXN,BAK1,PCNA,TNFAIP3,HBA1,CRYAB,PRDX3,GPX1,RPS3,IL18BP,MIR107,SOD2 |
| 1.683e-03 | -6.39 | regulation of glycoprotein biosynthetic process | biological process | GO:0010559 | 55 | 27 | 18204 | 5365 |
CTNNB1,NCSTN,MIR298,MIR455,MIR101-1,CHP1,MIR144,IGF1,ITM2A,IL15,HBEGF,MIR153-1,ACOT8,POMT2,CCL19,MIR147A,CCR7,ITM2B,MIR106A,PXYLP1,FKTN,MIR31,PLCB1,AATF,MIR20A,CCL21,MIR17 |
| 1.684e-03 | -6.39 | regulation of mononuclear cell migration | biological process | GO:0071675 | 143 | 59 | 18204 | 5365 |
IL34,TNFRSF14,CXCL10,CD200R1,LGALS3,CCL2,MSTN,CCR1,RARRES2,CD99L2,CCL1,PLCB1,CCL21,CD9,CRKL,CD81,MSN,MIR146A,CXCL13,CCR2,AIF1,DEFB124,MIR24-1,CX3CL1,XCL1,MMP14,MADCAM1,CALR,TNF,CCL5,CD47,MED23,PADI2,SELENOK,DUSP1,P2RY12,CCN3,CX3CR1,IL12A,CXCL12,DDT,AKT1,HMGB1,MMP28,WASL,CCL3,MIF,PYCARD,CREB3,CD200,ADTRP,CCL20,AGER,STAP1,GREM1,EMILIN1,CCR6,OXSR1,CCR7 |
| 1.685e-03 | -6.39 | Glucocorticoid receptor regulatory network | Pathway Interaction DB | reg_gr_pathway | 82 | 42 | 2226 | 782 |
CREB1,SUMO2,EGR1,IL6,PPP5C,FKBP4,MAPK10,EP300,BAX,STAT1,IL5,CSF2,PRL,JUN,IFNG,CREBBP,BGLAP,YWHAH,TP53,IRF1,CDK5R1,IL13,IL4,KMT5B,POU1F1,PRKACB,CXCL8,STAT5A,FOS,NFKB1,CDK5,MDM2,SFN,TSG101,VIPR1,PCK2,IL2,CDKN1A,NR1I3,AKT1,ICAM1,HSP90AA1 |
| 1.690e-03 | -6.38 | HUS1 (HUS1 checkpoint clamp component) | protein interactions | 3364 | 117 | 48 | 19454 | 5460 |
ATG101,NTAQ1,RFC5,MCM4,OGG1,PTTG1,RIT1,BRCA1,CSNK2B,CD79B,SCN2B,METAP2,UMPS,GTF2H4,ZNF574,RPA2,SDCBP,COX6C,EXOSC4,PRIM2,RPA3,RFC4,TRA2B,CD200,LAMP3,CSNK2A1,COPS5,TNNC2,DNAJC7,TOPBP1,SKIC8,POLB,ANAPC13,PPP2R1A,FEN1,RRM1,MRPL11,RAD1,DCUN1D5,PCNA,SDHC,MRPL22,COPS4,RIGI,RFC2,MSH6,PSMA2,ZBTB14 |
| 1.690e-03 | -6.38 | ARL14 (ADP ribosylation factor like GTPase 14) | protein interactions | 80117 | 117 | 48 | 19454 | 5460 |
DGCR8,YKT6,NF2,CDC42EP4,ARFIP1,CDC42EP2,SLC12A2,STOM,EHD1,SNX3,SMURF1,SH3BP4,SRC,NECTIN2,FAM83B,LAMTOR1,CCT2,MYO6,WDR20,SLC38A1,CSK,AKAP12,CCT8,DLG1,EFNB1,SNAP23,CASK,MARCKSL1,DLG3,CTDSP2,SNX1,MRPS9,PCDH9,UBE2G2,ADD1,SLC39A10,NEO1,FLRT2,LDLR,CDCA3,C2CD4C,SLITRK5,ESYT1,LCN8,PPP3CA,RELL1,GRSF1,PPFIBP1 |
| 1.690e-03 | -6.38 | IDH1 (isocitrate dehydrogenase (NADP(+)) 1) | protein interactions | 3417 | 117 | 48 | 19454 | 5460 |
IDH3B,NUP62,SHOC2,CDK1,RPA2,ADSS2,AGGF1,IDH2,HSPA8,RPA3,BAP1,IDH3A,PHB2,OXCT1,CUTA,TXNRD2,OAT,UBE2H,CHCHD4,CAB39,DKK3,POLR3H,ACOX1,EFHD2,CYRIB,ENO2,MYG1,TENT5C,SOX2,TP53,RANBP1,EZH2,CBX3,NME1,AGA,IDH1,ARF4,RIGI,SAR1B,RBBP7,HSPE1,TF,MOV10,AK2,AGR2,ZHX1,DCK,TMPO |
| 1.690e-03 | -6.38 | SCARNA22 (small Cajal body-specific RNA 22) | protein interactions | 677770 | 117 | 48 | 19454 | 5460 |
SF3B1,DDX5,HADHA,XRCC5,AATF,GTF3C4,SF3A1,USP39,LMNA,PSPC1,CSTF3,ATP5F1B,ACTB,RBBP4,NONO,SMARCA5,HNRNPC,HNRNPAB,CDKN2AIP,MECP2,LMNB1,EWSR1,RUVBL2,DHX9,HSPD1,TOP2B,HNRNPK,STRBP,ILF2,SART3,RPN1,HP1BP3,SYNCRIP,TMPO,CDC5L,HSP90AB1,HNRNPL,NOP58,TOP1,CCAR2,HNRNPA1,PRPF19,DDX50,BAZ1B,IFI16,HNRNPD,DDX1,MPHOSPH10 |
| 1.691e-03 | -6.38 | BLM (BLM RecQ like helicase) | protein interactions | 641 | 235 | 87 | 19454 | 5460 |
RPL23A,RABGGTB,RPS24,RPL31,RBM3,RPS13,RPS27A,MSH6,FANCG,H3C1,ASF1A,H2AX,TUBA1A,JUN,FEN1,SUPT5H,TP53,RAD23B,RNF8,CBX3,AKR1B1,ARL4D,PSMB1,FAAP100,SRP14,KRR1,EGLN3,KLF9,MIOS,CAND1,RPS16,SUMO3,RPL7,SUMO2,TRIM15,MIF,COPS5,PSMD3,TRIM8,MAGOH,MAP4,FOXP1,LHX2,TOPBP1,CHCHD1,H2AC4,NUP50,DVL2,RFC4,RPA3,NLE1,SIRT7,PML,NBN,COIL,H2AC13,FBXW7,MX1,KLF12,ELK4,RPL27A,RPS14,SUMO1,RPL26L1,RPA2,APOBEC3C,MAP2K1,ZMYM2,CSNK2B,UBE2I,EIF4A3,ZNF330,APEX1,ESR2,RPL19,SNRNP40,FBXO22,DYNLL1,AIPL1,PSMD1,RMI2,MYC,HSP90AA1,RMI1,MECP2,RBBP8,BRCA1 |
| 1.692e-03 | -6.38 | E6 (transforming protein) | protein interactions | 1489047 | 52 | 25 | 19454 | 5460 |
CREBBP,CCNB1,MAP1S,TMEM106C,TFDP2,BCL10,BRCA1,PPM1B,TADA3,SMAD2,SMAD3,SRPRA,SDC4,PSMB5,PSMB1,TPD52,SIPA1L1,TM4SF1,CDKN1A,MAP3K11,EP300,IRF7,B2M,SRPRB,UBE2A |
| 1.692e-03 | -6.38 | STK10 (serine/threonine kinase 10) | protein interactions | 6793 | 52 | 25 | 19454 | 5460 |
RHOB,NONO,CD81,XPO1,RAB11A,LAMP2,MOV10,HSPA14,CAV1,VIRMA,PRNP,TXN,ARF6,HNRNPL,MSN,MAP1LC3A,ENO1,MRPL53,AIFM1,BORCS8,TANK,TOP3B,RIGI,KRAS,NUP50 |
| 1.692e-03 | -6.38 | MAST2 (microtubule associated serine/threonine kinase 2) | protein interactions | 23139 | 52 | 25 | 19454 | 5460 |
TRAF2,SOX2,TOP3B,OTULIN,SNRPA,RPS27A,SMN1,YWHAH,YWHAG,TPM3,CUL3,SFN,HSP90AA1,YWHAB,TRAF6,BICD2,YWHAZ,FBXW11,PTEN,SRPK2,VIRMA,SNRPB2,DYNLL1,PRNP,SUMO2 |
| 1.692e-03 | -6.38 | CEBPE (CCAAT enhancer binding protein epsilon) | protein interactions | 1053 | 52 | 25 | 19454 | 5460 |
RB1,UBE2I,CEBPG,ZMYM2,CCT7,CEBPE,ATF4,TAF5L,TRIB1,HSP90AA1,DDIT3,EDA2R,ATF3,FOS,RIGI,PIAS1,LDOC1,MLLT6,JUN,SIPA1L1,BATF,STAT6,GPR22,IL7,CSNK1A1L |
| 1.692e-03 | -6.38 | ATP5F1E (ATP synthase F1 subunit epsilon) | protein interactions | 514 | 52 | 25 | 19454 | 5460 |
MTRES1,CAV2,DHRS4,AGTRAP,COQ8B,ATP5F1D,NME4,ATP5IF1,HSPA8,HINT2,ATP5PF,CYP17A1,NDUFA4,PPM1B,ATP5F1A,FMC1,NDUFAF4,ATP5F1B,TES,GATD3,PTPMT1,UBE2N,CTDSPL2,SSBP1,AIFM1 |
| 1.701e-03 | -6.38 | regulation of interferon-alpha production | biological process | GO:0032647 | 30 | 17 | 18204 | 5365 |
TLR8,NMBR,IRF3,TBK1,TLR4,IFIH1,TLR9,IRF7,TLR7,RIGI,STAT1,DHX9,MAVS,HSPD1,TLR3,NMI,IL10 |
| 1.706e-03 | -6.37 | C9orf78 (chromosome 9 open reading frame 78) | protein interactions | 51759 | 616 | 206 | 19454 | 5460 |
EXOC5,TRIM32,SMARCA5,SUGP1,CCNB1,CSTF3,PPP1R10,SMURF1,INTS12,PPP2R5E,UQCRC2,CYC1,RPA2,EIF2B3,GTF3C4,GTF2H4,SUMO1,HSPA5,KDM1A,WDR3,DLAT,GFM1,APMAP,NBN,KPNA1,TSNAX,MAP4,COPS5,RBM42,TMPO,CDC5L,ADD1,GNPAT,COQ8A,CAPN2,EXOC3,GPD2,CBX3,IK,ACADSB,TP53,PDE12,H3C1,NEDD8,NUP107,CSE1L,PCYOX1L,SLC25A11,H2AZ2,FBXW11,HMGCS1,PSMD1,MYC,POLR2B,KBTBD6,NCKAP1,ALG5,MATR3,SNRNP40,INTS10,ZMYM2,ANAPC2,DLST,FDFT1,ACAA2,SEC62,NUP62,NDUFS2,FAM50B,TNNC2,XPO1,EXOC1,HSP90AB1,MEAF6,DYNC1I2,MAGED2,SIN3A,MTA2,AAMP,UCK2,TNPO2,HEXA,SUPT5H,CDCA7L,MYO1B,EWSR1,AP2A1,XPOT,NAPA,HERC4,ATP5F1A,TUFM,RACGAP1,CDC16,CIAO1,PELP1,LMNA,PICALM,TMX4,UQCRC1,ELP3,RBFOX2,PSMC4,SYNGR2,PIP5K1A,YKT6,GTF2I,PDHB,SMC4,MTDH,RTN4,SQSTM1,RPA3,NCDN,IDH3A,CNN3,OSBPL8,ESYT1,EXOC2,ECD,LRRC40,ORC5,ERCC3,EIF2B5,PWP2,SRPRA,CASK,DMAP1,NDUFS3,CD2BP2,BCS1L,UBR7,MTA3,H2AJ,ARF4,RNF20,FASTKD5,VPS16,MSH6,CNOT7,ZC3H11A,TMX3,HSD17B10,PPP1R12A,NSDHL,PQBP1,SFXN1,EXOC8,BAX,SETD7,ELMO2,MYO6,TOMM40,RFC5,MCM4,CUL2,FCHSD2,TNPO3,RBBP4,MED17,TAB1,AP2M1,POLR3B,LRRC1,FAM91A1,FKBP10,SLC25A3,MED23,USP39,IDH3B,POLA2,PYGB,PSMC1,NUBP2,NUP50,HADHA,NKAPD1,NAB2,HAX1,AHSA1,CDK5RAP3,DDX23,WDR11,PSMD3,MAP1S,PPP2R5A,NDUFS8,OCRL,AGK,SNX2,ATXN10,TSG101,XPO5,ATP6V1A,COPS2,DNM2,WDR6,BZW2,PPP2R1A,AP1M1,MCM6,RAD21,HS2ST1,RFC2,HSPD1,SYPL1 |
| 1.713e-03 | -6.37 | MANF (mesencephalic astrocyte derived neurotrophic factor) | protein interactions | 7873 | 74 | 33 | 19454 | 5460 |
MED4,UBE2H,DNAJB6,MICB,DPP4,CTSB,NUP35,ZBTB2,SLAIN2,ADAM21,LDLR,SEC61B,TCP11L1,TFRC,CZIB,CHMP4C,FGF10,AP2S1,ATG16L1,ATP5PB,TPT1,TIMMDC1,CNPY3,MSX2,ZDHHC17,MRPS18C,CDNF,HSPA5,EIF2D,TMEM106B,HNRNPA2B1,ANAPC16,MYO1B |
| 1.713e-03 | -6.37 | LPCAT3 (lysophosphatidylcholine acyltransferase 3) | protein interactions | 10162 | 74 | 33 | 19454 | 5460 |
CSGALNACT1,UPK1A,CCR6,OPRM1,GPR17,PTDSS1,OPRL1,VIRMA,TNFSF18,SPPL3,HNRNPL,IL2RA,CHRM4,CD63,CRELD1,CAPZA2,AQP3,RPA2,HCST,LPAR6,SLC5A6,PDE2A,FBXL4,LPAR1,TACR1,VIPR1,SYVN1,SLC22A6,PML,ATP5PF,TSPAN15,CXCR4,RPA3 |
| 1.713e-03 | -6.37 | ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2) | protein interactions | 8233 | 74 | 33 | 19454 | 5460 |
SNRPD3,RPS27L,FZR1,SRPK2,SRSF1,REP15,RBM5,SF3B6,ZMAT5,SNRPD2,ZCRB1,RIT1,RPL10A,SSX2IP,SPATS2L,RBM17,TTC33,SNRPB,SNRNP48,KRAS,SRSF2,SNRPG,EMC2,CLK1,SF3B1,TNFAIP8L1,SNRPE,RPL26L1,SNRPN,TP53,KHDC4,SF3A1,RPL15 |
| 1.713e-03 | -6.37 | ELL (elongation factor for RNA polymerase II) | protein interactions | 8178 | 74 | 33 | 19454 | 5460 |
RIT1,FGFR1OP2,SNRPA1,DYNLL1,CCAR2,NCBP2,CDK9,MAD2L1,CDC5L,EAF2,ESR2,MID1IP1,ZHX1,MFAP1,MOB3C,ACACA,TOP3B,TP53,DENND2D,ASPM,CDK7,HUWE1,KRAS,CAMKV,HDAC3,ASF1A,FGF12,NSDHL,TFPT,SIKE1,HDAC5,BCAP29,EP300 |
| 1.713e-03 | -6.37 | GLI3 (GLI family zinc finger 3) | protein interactions | 2737 | 74 | 33 | 19454 | 5460 |
CSNK1A1,RPS11,PRKCA,YTHDF2,SUFU,SMAD1,SOX2,YTHDF1,KRAS,NUP107,RIGI,SAP18,TOMM20,RCCD1,RHOU,HSPD1,FBXW11,SMAD4,SPOP,PFDN4,TAF9,SMAD2,CEP85,MYC,CREBBP,AR,HDAC6,VIRMA,EGLN3,ARL10,KLHL7,SMAD3,GSK3A |
| 1.714e-03 | -6.37 | LPAR2 (lysophosphatidic acid receptor 2) | protein interactions | 9170 | 120 | 49 | 19454 | 5460 |
ARL6IP5,DERL2,MSMO1,RMND1,PTPN1,SLC39A10,STARD3NL,FAM241B,PPM1B,EI24,SIVA1,FAM20B,TNFSF8,SACM1L,SURF4,TMEM126A,PREB,YIPF3,MGST3,CD47,LGALS3,SLC25A31,ACP2,B4GAT1,SEC63,SCAMP2,SLC30A7,CNIH4,KDSR,HMOX2,CNNM4,CMTM6,ZDHHC17,BCL6,CERS6,TMEM160,ATP2C1,HSDL1,CORO6,TSPAN15,LRP10,TAPBP,GALNT1,GOLGA5,HBB,TMOD1,FDFT1,FUT8,SEC62 |
| 1.714e-03 | -6.37 | TMEM201 (transmembrane protein 201) | protein interactions | 199953 | 120 | 49 | 19454 | 5460 |
FZR1,DNAJC1,NUP35,MINAR1,OS9,TMEM237,EGLN3,TMPO,STYK1,PTPN5,FATE1,TMT1A,STX18,TMEM268,RPN1,STIM1,CRELD1,LGR4,DNAJC25,B4GAT1,ESR2,APLNR,CYB5R3,LMBR1L,CCNF,SEC61B,CGRRF1,BICD2,MARCHF3,CUL3,NDUFAF2,MYC,VEZT,STAU1,PXMP2,TSPAN15,CXCR4,TMX2,DERL1,EP300,VIPR1,UBAC2,GP9,SSR1,LMNA,RPA2,ST7,SEC62,OTULINL |
| 1.714e-03 | -6.37 | MED24 (mediator complex subunit 24) | protein interactions | 9862 | 120 | 49 | 19454 | 5460 |
PML,NR1I3,MED13L,MED11,FBXW7,ATG16L1,MED30,FBXL19,MED23,PPARG,TFIP11,MED31,LMBR1L,PSMD4,MED17,POLR2B,SMAD5,ESR2,MYC,LMO2,MED22,AR,MED10,STN1,SMAD2,TRIP4,TOP2B,EMC2,MRPL22,FBP1,VDR,MED9,JUN,PPARA,SERPINA3,RPAP2,SMAD1,CDK8,MRPL36,MRPL33,SMAD3,MRPL24,MED21,MED27,MED29,MED4,HNRNPD,SMAD9,BRD3 |
| 1.714e-03 | -6.37 | TMOD3 (tropomodulin 3) | protein interactions | 29766 | 232 | 86 | 19454 | 5460 |
PABPC1,DHX9,RUVBL2,TRIM37,TNF,PSMA1,G3BP1,KRAS,AHCYL1,DUSP19,FBXO25,PPIL3,MED9,ISG15,SOX2,MAP1LC3B,DISC1,CAPZA2,CHMP4C,TFCP2,TFRC,EZH2,TBC1D4,FURIN,NUPR1,RND3,MTA2,ACTA2,COX4I1,PRNP,CDC5L,DHX15,FHIP1B,CDK9,TMPO,EMC4,PSMD3,DPP4,IFI16,CTNNB1,CSNK2A1,XPO1,PPM1D,HDAC6,SNRNP70,BCL2L1,FBXO34,CBL,PML,PRPF4,FOS,BAP1,DDX39B,RPA3,NMRAL1,FBXW7,HSPA5,PSMC4,CFTR,NEK2,CDC42,PPP1CB,FGFR1,GRM2,PSMB7,RPA2,ARCN1,CCNF,SNRPD1,MOB4,ACTB,STAT1,DAPK1,DYRK1A,ESR2,USP5,VIRMA,SH3BGRL,RAB11A,CUL3,MYC,AR,PPP1CC,USP14,BTF3,UBE2H |
| 1.717e-03 | -6.37 | negative regulation of interleukin-17 production | biological process | GO:0032700 | 23 | 14 | 18204 | 5365 |
TLR4,DDIT3,TUSC2,ARG2,PRNP,IL12B,MIR136,IFNG,MIR383,MIR181C,FOXP3,IL12A,MIR20A,VSIR |
| 1.717e-03 | -6.37 | relaxation of muscle | biological process | GO:0090075 | 23 | 14 | 18204 | 5365 |
GSTM2,RGS2,KCNJ2,P2RY1,PLN,PIK3CA,ATP1A2,SOD1,SLC8A1,MIR153-1,KBTBD13,ATP1B1,CHGA,ATP1A1 |
| 1.719e-03 | -6.37 | COQ5 (coenzyme Q5, methyltransferase) | protein interactions | 84274 | 91 | 39 | 19454 | 5460 |
EGLN3,APLNR,RMND1,PTPMT1,GATD3,COQ8A,SSBP1,SCN2B,CCDC90B,DPEP1,PYURF,DNAJC19,MRPL18,AUH,MTG2,CLPX,MTRF1,PMPCA,MRPS35,FAM174A,GPR17,FASTKD5,POLDIP2,IMMP2L,HSCB,CD80,NPTN,DNAJC30,HINT2,GFM1,HSPD1,EXD2,GFM2,SPRYD4,PDHA1,GTPBP8,NPY2R,METTL15,COQ8B |
| 1.724e-03 | -6.36 | positive regulation of protein catabolic process | biological process | GO:0045732 | 204 | 80 | 18204 | 5365 |
STUB1,GCLC,CLU,PSMC1,USP13,TNFSF12,SUMO2,IL1B,AKT1,LDLR,ASB11,VPS28,BAG2,NOP53,OAZ2,SNX33,HSP90AA1,FBXW7,GABARAP,SOCS4,RNF128,RNF41,DTL,MDM2,TNF,STX5,DDRGK1,PACSIN3,IFNG,ZFAND2A,OAZ3,IER3,SEC22B,TRIM32,RCHY1,TNFAIP3,ZER1,CSNK1E,RHBDD3,OAZ1,NUPR1,PSMC4,FZR1,CDC20,COP1,CDKN1B,SOCS5,CSNK2A1,ATG7,TNFRSF1B,HECTD1,SOX9,NDFIP1,MYLIP,PSMC3,IDE,PIAS1,PSEN1,VIP,SGTA,MSN,CD81,CSNK1A1,TRIB1,DNAJB2,NFE2L2,CAV1,PSMC5,PSMD10,DET1,FURIN,PCSK9,EGLN2,FBXO22,GSK3A,VGLL4,FAF1,USP5,RGMA,SUMO1 |
| 1.733e-03 | -6.36 | respirasome | cellular component | GO:0070469 | 91 | 40 | 19108 | 5553 |
NDUFB5,NDUFA12,COX8A,BCS1L,NDUFB8,NDUFB6,UQCRC2,COX6A2,NDUFA5,COX4I1,COX7B,UQCRQ,CYC1,NDUFV2,NDUFB4,COX6B2,COX4I2,NDUFB10,UQCC3,UQCR11,NDUFA1,COX6C,NDUFC2,NDUFS8,NDUFB7,COX5A,SDHC,COX7B2,NDUFS6,UQCRH,NDUFA4,NDUFA2,NDUFS2,HIGD2A,COX6B1,COX7A1,NDUFS3,SDHB,NDUFAB1,UQCRC1 |
| 1.734e-03 | -6.36 | PTPMT1 (protein tyrosine phosphatase mitochondrial 1) | protein interactions | 114971 | 186 | 71 | 19454 | 5460 |
FKBP8,IMMP2L,MSH6,CSE1L,CHCHD2,KRAS,COX8A,SLC16A1,CLPB,ATP5PF,SFXN1,TMEM14B,NDUFS3,AQP3,PDHA1,HINT3,IPO8,MTCH2,SNAP29,ATP5PB,ATP5PD,ATXN10,GATD3,DUSP6,COQ8A,ACSL4,DICER1,TMEM70,RHOG,DDRGK1,HDAC6,COPS5,ATG7,COX5A,STOML2,LAMP2,MDFI,CLPX,POLDIP2,FTL,FBXW7,SLC25A51,OXCT1,ATP5F1E,PML,RCCD1,ATP5MK,SLC25A3,GRM2,ATP5PO,PAK5,MRPL12,VIRMA,PARL,CPT2,SIAH1,TAB1,PTPMT1,SLC1A1,TRIM27,KRTAP3-1,CCDC90B,CCNF,LMBR1L,UQCRC2,DNAJC19,RIT1,XPOT,CISD1,SLC25A1,NDUFAF2 |
| 1.734e-03 | -6.36 | ARL10 (ADP ribosylation factor like GTPase 10) | protein interactions | 285598 | 186 | 71 | 19454 | 5460 |
RPL10,LDHA,KBTBD2,HEY2,IL2RA,FAM91A1,RPS3,CHRM5,CHRM4,IGF2BP1,HSP90AA1,BAX,RPS5,NR2E1,CD226,ATP5F1A,PCCB,TACR3,YKT6,NF2,HSCB,LPAR1,AKAP1,MAVS,DUSP9,UGDH,RPS28,EXD2,SCLT1,ACACA,LEMD3,P2RY12,ARMCX3,VIPAS39,TOMM22,CHST7,SEC22B,PPIA,SURF6,VTI1B,CAND1,RPL7,MAGED2,STX5,PTPN1,RPL9,PHB1,KCNJ10,RPL24,LAMP3,PPFIBP1,WDR11,SPATA2,RPS27A,FKBP8,RPL17,HSPE1,RPL3,PCNA,DHX9,PC,RPL31,RNF121,FAF2,LBR,EEF2,RPL15,ERLIN2,MIEF1,SNAP29,CHRM3 |
| 1.735e-03 | -6.36 | PFDN4 (prefoldin subunit 4) | protein interactions | 5203 | 123 | 50 | 19454 | 5460 |
GRPEL1,NUP50,PRPF4,PPM1G,DUSP9,SCLT1,SAMM50,TANK,UBB,TUBB,ACTB,SPIN3,TRAF7,ZBTB33,ELK3,RAN,TUBA1B,CREB1,SORD,PFDN6,PFDN2,UHMK1,CDC73,RC3H2,FBXW11,TTC33,MYC,DUSP19,PFDN1,PDRG1,PCGF3,DYNC1I1,G3BP1,POC1B,CCT8,OTULIN,TUBB4B,GFPT1,TUBA1A,CCT7,SLMAP,DYNC1I2,FZR1,MIOS,EEF1AKMT3,SKIC8,DCAF5,SPATA2,B9D1,PFDN5 |
| 1.737e-03 | -6.36 | Interleukin-3, 5 and GM-CSF signaling | REACTOME pathways | R-HSA-512988 | 271 | 108 | 10285 | 3229 |
PIK3CA,PEA15,PSMA6,PSMD1,PSMB2,PPP2CB,LAMTOR2,KIT,HRAS,IL5,PSMC1,CUL3,VWF,IL2RB,CAMK2G,LAMTOR3,FGF16,PHB1,PSMD4,SPRED1,RPS27A,IL3,PSMA1,PSMC3,DUSP1,SEM1,PSMB4,RASGRP3,SHC1,PEBP1,PSMB3,YES1,SPTAN1,PPP2R5E,FGF23,PSMA5,MET,PAQR3,DUSP6,FGF1,PPP2R5A,YWHAB,IL2RG,PIK3R2,RAF1,SYK,FGF22,UBA52,WDR83,MAP2K1,KRAS,RAP1B,YWHAZ,FGF10,SRC,DUSP9,FRS3,PSMD10,RAP1A,SHC3,PSMD12,JAK1,FGF7,PIK3R3,CSF2,DUSP10,NEFL,MAP3K11,PSMB9,IL2RA,SPRED2,PSMD6,HBEGF,FGF3,PSME2,DLG4,CSK,BRAP,PSMB6,PSMA2,PSMB11,IL2,FGFR1,PSMC5,PSMB10,PSMA4,PSMC4,PSMB5,PSMA3,PIK3R1,CRKL,PSMB1,PSMD3,PSMB7,JAK2,INPPL1,UBB,CBL,STAT5A,PPP2R1A,PTPN11,PSMD14,PSMD7,FGF17,PSME1,ANGPT1,SPTBN1,PPP5C |
| 1.738e-03 | -6.36 | Vitamin C (ascorbate) metabolism | REACTOME pathways | R-HSA-196836 | 8 | 7 | 10285 | 3229 |
GSTO1,SLC2A1,GSTO2,CYB5R3,CYB5A,SLC2A3,SLC23A2 |
| 1.739e-03 | -6.35 | E1A (control protein E1A) | protein interactions | 1460853 | 5 | 5 | 19454 | 5460 |
SMAD3,CDKN1B,SMAD2,EP300,SMAD1 |
| 1.739e-03 | -6.35 | Hipk2 (homeodomain interacting protein kinase 2) | protein interactions | 15258 | 5 | 5 | 19454 | 5460 |
RUNX1,UBE2I,MECP2,SUMO1,PML |
| 1.739e-03 | -6.35 | DPP10 (dipeptidyl peptidase like 10) | protein interactions | 57628 | 5 | 5 | 19454 | 5460 |
DPP10,BAG3,EZH2,KCND3,KCND2 |
| 1.739e-03 | -6.35 | TAS2R14 (taste 2 receptor member 14) | protein interactions | 50840 | 5 | 5 | 19454 | 5460 |
ATP5MG,ATP5PO,ATP5F1B,ACP5,APEX1 |
| 1.739e-03 | -6.35 | Arhgef7 (Rho guanine nucleotide exchange factor) | protein interactions | 54126 | 5 | 5 | 19454 | 5460 |
SMAD2,SMURF1,CDC42,SMAD4,SMAD3 |
| 1.739e-03 | -6.35 | KIF12 (kinesin family member 12) | protein interactions | 113220 | 5 | 5 | 19454 | 5460 |
CFTR,FBXO7,MMADHC,CLPX,LMNA |
| 1.739e-03 | -6.35 | CYP2D6 (cytochrome P450 family 2 subfamily D member 6) | protein interactions | 1565 | 5 | 5 | 19454 | 5460 |
CYB5A,ATRAID,CYP2D6,CYP2C9,POR |
| 1.739e-03 | -6.35 | US11 (tegument protein US11) | protein interactions | 2703439 | 5 | 5 | 19454 | 5460 |
HSP90AA1,APPBP2,EIF2AK2,TRIM23,IFI16 |
| 1.739e-03 | -6.35 | PIB1 (phosphatidylinositol-3-phosphate-binding ubiquitin-protein ligase) | protein interactions | 851908 | 5 | 5 | 19454 | 5460 |
UBE2D1,UBE2N,UBE2W,UBE2V2,UBE2V1 |
| 1.739e-03 | -6.35 | Lmo4 (LIM domain only 4) | protein interactions | 16911 | 5 | 5 | 19454 | 5460 |
IL6ST,SOCS3,JAK1,JAK2,PTPN11 |
| 1.745e-03 | -6.35 | polysaccharide metabolic process | biological process | GO:0005976 | 79 | 36 | 18204 | 5365 |
LEPR,CSGALNACT1,GABARAPL1,FUT9,NDST1,GSK3A,PPP1R1A,PPP1CC,GBE1,PYGM,NDST3,PPP1R3C,ATG3,PPP1CB,PHKA1,UGP2,STBD1,CHST7,WDR45,GYS1,PYGB,PPP1R2,IL6ST,HS2ST1,PHKG1,GNMT,AKT1,CSGALNACT2,PHKB,PTGES3,EXT1,AKT2,CHST1,COMT,HAS3,RB1CC1 |
| 1.747e-03 | -6.35 | PSIP1 (PC4 and SRSF1 interacting protein 1) | protein interactions | 11168 | 183 | 70 | 19454 | 5460 |
SRSF1,H2AZ1,DPY30,RPL6,SPATS2L,HMGA1,DDRGK1,CSNK2A1,AGR2,SNRNP70,BRD3,POU5F1,KPNA1,RPS24,ABCE1,EWSR1,HNRNPK,THRAP3,H3C1,POLDIP3,CDCA7L,RAF1,TOP3B,FBP1,TPBG,SOX2,NCSTN,PPP2R1A,EZH2,CBX3,RHOBTB1,RPS11,RBPJ,ZNF330,EIF4A3,SEC61B,MACROH2A1,CDC7,ESR2,RPL10,APEX1,LDHB,SUB1,MYC,USP14,RUNX1,FTSJ3,UBE2H,SP1,BANF1,HCFC2,RPA3,CXCR4,MTDH,EP300,SQSTM1,HSPA8,EXOSC4,STAU1,NUCKS1,UFL1,TRA2B,SAP18,SUMO1,CD2AP,CDC42,GRM2,METTL14,RPA2,LMNA |
| 1.753e-03 | -6.35 | RNF115 (ring finger protein 115) | protein interactions | 27246 | 126 | 51 | 19454 | 5460 |
KDELR1,TLR3,SERPINA3,DDX39A,H2AX,ISG15,RBCK1,RNF115,RAB13,TLR7,GLUL,RAB1A,TLR4,YWHAB,UBE2D1,YWHAH,YWHAG,PFDN5,CST3,UBE2E2,DNAJB2,MDM2,NRSN1,UBE2N,HRAS,HSP90B1,UBE2W,TANK,NT5C3A,UBE2D3,TTR,RAB5A,MAVS,BIRC2,SCN1B,PSEN2,TLR9,UBE2E3,YWHAZ,FBXW11,HMGCS1,SFN,AKT1,MYC,TAX1BP1,UBE2I,CALML5,KLK6,NFKBIA,PAPSS2,LMBR1L |
| 1.753e-03 | -6.35 | NTPCR (nucleoside-triphosphatase, cancer-related) | protein interactions | 84284 | 126 | 51 | 19454 | 5460 |
UFL1,RPA3,PML,RNF113A,RPA2,FGFR1,MET,STAMBP,PGRMC1,TANK,CDC42,CFTR,ESR2,MAD2L2,DYRK1A,CCNF,DLST,NTRK3,ZBTB38,UBE2H,COL1A2,AUH,MYC,CUL3,FBXO7,WDR19,EPHA4,RUVBL1,CDK20,MEPCE,MAP1B,RUVBL2,IGF1R,FURIN,TRMT1L,TOP3B,B3GNT2,TUBA1A,EPHB6,RAMP3,EGLN3,NUP35,AIFM1,PHB1,EEF1AKMT3,TUBG1,SSX2IP,DPP4,ATG9A,PPM1D,DDRGK1 |
| 1.754e-03 | -6.35 | T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection | WikiPathways | WP3863 | 62 | 34 | 5310 | 1910 |
IFNG,IL4,PDCD1,JUN,IL10,LCP2,NFKBIA,CHP1,CD28,GRAP2,RAF1,ICOS,AHSA1,CBL,CD4,CTLA4,PIK3CA,MAP3K14,NFKB1,IL2,TNF,CD40LG,CSF2,IL5,MAP2K1,FOS,AKT1,BCL10,IKBKB,DLG1,NCK1,PRKCQ,ITK,CDK4 |
| 1.759e-03 | -6.34 | SMARCA1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1) | protein interactions | 6594 | 180 | 69 | 19454 | 5460 |
CHRAC1,TXNIP,MYC,SMARCA5,TUFM,RBBP4,SNRNP40,VIRMA,SRC,APEX1,ZNF330,MACROH2A1,RPA2,RFXANK,HMGB1,STAU1,FBXW7,NUCKS1,UFL1,FTL,COIL,MBD3,RAB5A,NCK1,LHX2,BRD3,KPNA1,RPS2,DPY30,WWP2,HMGA1,BAZ1B,IFI16,DDRGK1,CGAS,TOP1,BRMS1L,SHPRH,PGR,KLF9,ZBTB2,POLE3,PHB1,SIN3A,H2AZ1,GATAD1,EED,MYBL2,NECAP1,EZH2,CBX3,NUPR1,MTA2,RBPJ,TP53,RAF1,MAX,MTA3,SAP30,H2AX,VRK1,RUVBL1,H3C1,RBBP7,G3BP1,SSRP1,PTGES3,PHF1,TFPT |
| 1.761e-03 | -6.34 | proton-transporting ATP synthase complex | cellular component | GO:0045259 | 21 | 13 | 19108 | 5553 |
ATP5F1B,ATP5PO,ATP5PD,ATP5F1E,ATP5MK,ATP5F1D,ATP5PB,ATP5MC1,ATP5MG,ATP5F1A,ATP5MC3,PPIF,ATP5PF |
| 1.761e-03 | -6.34 | proteasome regulatory particle | cellular component | GO:0005838 | 21 | 13 | 19108 | 5553 |
PSMD6,PSMC4,PSMC3,PSMD3,PSMD7,PSMD12,PSMC1,PSMD14,PSMD10,PSMC5,ADRM1,PSMD1,PSMD4 |
| 1.763e-03 | -6.34 | RBFA (ribosome binding factor A) | protein interactions | 79863 | 63 | 29 | 19454 | 5460 |
HECTD3,YIF1A,COX8A,SYPL1,LEPROTL1,CDC42EP4,HIGD1C,CMTM6,METTL15,ABHD5,ATG16L1,AGTRAP,MRPL11,CTLA4,PDHA1,GATD3,SCN2B,ERLIN1,KBTBD6,DERL2,RPL35,ANAPC15,CAV3,KLHL22,FATE1,AUH,MRPS26,UBE2H,SYP |
| 1.763e-03 | -6.34 | IFNGR2 (interferon gamma receptor 2) | protein interactions | 3460 | 63 | 29 | 19454 | 5460 |
INSIG2,FUT8,SEC22B,IFNGR1,SFTPC,CXCR4,JAGN1,CLEC7A,UNC50,TMEM254,ENTPD3,EMP3,TMEM60,ADIPOQ,SMIM11,SFT2D2,IFNG,TMEM199,KDSR,PMP22,ZDHHC24,ATP5MC1,RETREG3,RPL37A,COG1,PEX13,CXCL9,TMEM97,JAK2 |
| 1.763e-03 | -6.34 | NUDT5 (nudix hydrolase 5) | protein interactions | 11164 | 63 | 29 | 19454 | 5460 |
SKA3,RPA2,NUDT3,DUSP14,HEXA,STAU1,EWSR1,DDX5,SKA1,BAP1,PPP1R12A,DNAJC3,NUDT5,IRF3,UBE2H,LAMTOR1,BICD2,GORASP2,CTNNB1,IFI16,PYCR2,PYCR1,SMURF1,ROCK1,MAD2L1,PPAT,PRNP,DFFA,CCNF |
| 1.765e-03 | -6.34 | NR3C1 (nuclear receptor subfamily 3 group C member 1) | protein interactions | 2908 | 950 | 307 | 19454 | 5460 |
DBT,ATP5PD,MDM2,KCNMB2,TOP1,DERL2,ARF6,TES,MYBL2,UBP1,SMAD3,TFE3,C1GALT1C1,DNAJC7,ECD,MPHOSPH10,POR,HM13,HDAC6,NFKB1,RNF14,CALR,H2AC14,PTGES3,TF,CAMK2G,NSDHL,DTD1,TMEM156,ALG11,TCAF2,CCDC47,VIRMA,SEC63,UBB,UBE2L3,UQCRQ,SLC25A4,TXN,TRIM24,UBE2I,STUB1,PELP1,SDF2L1,HMOX2,TUFM,NONO,AR,ATP5F1A,ZNF687,PYCR2,AATF,SS18,NHP2,PIAS1,HMGB1,FBXW7,USP8,PDHB,RTN4,FLCN,MYH2,RPA3,HELLS,MACROH2A2,HNRNPH3,NOL7,EPHX1,MANBAL,HSP90B1,FTH1,LPXN,UBA52,NFYB,PCK2,SF3A1,RBFOX2,RABL3,ATG16L1,BUD31,NYAP2,AGK,TSG101,MYEF2,DNM2,HNRNPD,TRA2A,HNRNPA1,ADCY2,TRIM8,DPY30,MRPS35,PDE6A,PRELP,ETFA,ATP5F1D,WDR19,ZBTB16,BAG2,UBE3A,PLCB1,HECTD3,SYPL1,TMT1A,PPAN,ATF3,HSPD1,PREPL,CYB5B,AZIN2,PPID,VPS33A,RPN1,HOXB1,JUN,FAF2,GFPT1,RAF1,HSDL2,GNB1,CHCHD3,TUBB,MED17,MRPL23,PIGK,RAN,PFDN6,ARMT1,HSP90AA1,SP1,CNIH4,RHOB,MYO6,SMARCE1,HBEGF,RHEB,PYCR1,CUL3,RAB11A,DSN1,G3BP2,TGFB1I1,NAP1L3,NUBP2,HADHA,THAP2,PPARG,USP39,RAB6A,STXBP1,IDH3B,PRDX3,TOR1AIP2,SLC38A2,TMED9,CD4,UBE2N,ACSL4,COQ8A,SSBP1,MRPS9,KPNA1,SMCHD1,NR2F6,USP2,COX5A,KARS1,ACOT8,CMSS1,KPNA2,H3C1,SLC16A1,ABCE1,NOSIP,TAF2,CERK,TAB2,DCAF12L2,TMEM165,RBM34,ACADSB,SURF4,TFRC,TP53,STRBP,IMP3,SRC,IDE,GRPEL2,CTSB,DAPK1,IRF2BP1,STAT5A,SGTA,CALML5,LIG3,CDIPT,CREB1,RRP7A,CALU,SERPINB1,TBC1D25,ATP1A1,POU1F1,ELAVL2,NR0B1,MED22,IFI35,SUGP1,HSPA5,MRPL41,CRYL1,RBM22,KDM1A,DLAT,DERL1,ZBED3,PML,NBN,ORC6,MAIP1,BAP1,APMAP,LIN7C,SUPT7L,SSR1,HBB,RPA2,RPRD1B,NTPCR,CD2AP,MRPL10,POLR1D,SUMO1,AKR7A2,HSP90AB1,LANCL1,UQCRH,OSBP,NOB1,RAB1B,PPFIA3,S100A8,HOMER3,GYS1,MPDU1,SRSF1,CBL,FKBP4,UTP6,CTNNB1,NGDN,YWHAH,NDUFV2,CNOT8,HNRNPDL,DRP2,PFDN1,VDAC1,PDIA6,SEC11A,BCL9,AAMP,MTA2,SMARCB1,RAB4A,PDHA1,TUBB4B,FOXJ3,MSX2,TRAF2,MORC4,LRIF1,PPP5C,ATP5F1B,CAVIN2,CD3G,ZMYM2,DLST,NFKBIB,ZHX3,PHF12,SERPINH1,ZMPSTE24,NSA2,OSGEP,SLC38A1,RPS26,ICAM1,MRPS25,SPCS3,SLC1A3,SFN,CREBBP,MRPS7,EEF1G,NDUFS2,FXR2,EP300,HSPA8,SLU7,JAGN1,FDFT1,PPT1,MRPL12,IL22,KLHL3 |
| 1.766e-03 | -6.34 | LIMA1 (LIM domain and actin binding 1) | protein interactions | 51474 | 409 | 142 | 19454 | 5460 |
SH3BGRL,SH3BP4,VIRMA,TMOD3,RALA,DAPK1,DAPK3,YES1,PTEN,CCNF,AP2A1,TBC1D25,UBE2H,MAPRE1,RAP2C,CFL2,ARHGAP21,DEPDC1B,CFL1,PPP1CC,USP14,GSTK1,FAM110B,TOMM20,PIAS1,HSPA5,FAM53C,TNFAIP1,RPA3,DDX46,BAP1,PML,TMOD1,AGAP1,CSNK1G3,RPA2,JUP,PICALM,STOM,METTL14,FGFR1,SIPA1L1,GABRA1,CDC42,CFTR,CDK7,PSMC4,ATG16L1,SPTBN1,TPT1,CAV1,KCTD3,PPP1R18,FCHO2,RAP1B,DECR2,TES,AIFM1,EIF4E2,TUBG1,TIAM1,HDAC6,EDC3,MOV10,PHF1,SRSF12,CAPZA1,ERLEC1,TOLLIP,HAPSTR1,CYBRD1,PALM2AKAP2,FAF1,RAB1A,NUPR1,STARD13,PSMC3,ACTR2,IK,DISC1,ARPC3,CAPZA2,MAP1LC3B,KBTBD4,FBP1,TP53,RPSA,KIF1C,RAP1A,PPP1R3C,NCKAP1,STAT1,ACTB,AP2M1,RRAS2,EFHD2,CDKL2,YWHAZ,BTF3,PSMD1,MAP3K21,MYC,CUL3,SFN,POLA2,PSMC1,PACSIN3,UFL1,UCHL3,DDX39B,FOS,RTKN,MYL6,PPP1CB,ELK4,INPP5E,WDR77,SPTAN1,KCTD10,CORO1C,RPL23,YWHAB,CAMSAP2,BCL7C,YWHAH,YWHAG,UBXN6,RAB5C,CCAR1,FLOT1,KRAS,TRIM37,MYO1B,TESK2,MTA2,EZH2,PDHA1,SOX2,ACTN4,CRYGD,TOP3B,B3GNT2 |
| 1.769e-03 | -6.34 | EIF2B4 (eukaryotic translation initiation factor 2B subunit delta) | protein interactions | 8890 | 129 | 52 | 19454 | 5460 |
XPO1,DDRGK1,TSPAN10,FAM174A,SMDT1,SNRNP70,CD4,TES,PCDH9,DNAJC1,EIF2S1,VTI1B,HNRNPL,EIF2B5,EIF2B2,SOX2,CLEC2B,COMTD1,RAF1,STX12,CA14,SIGLECL1,BZW2,EFNB1,MYC,GPR17,RIT1,FTSJ3,TRIM23,CD226,SYT2,EIF2S2,CCNF,LMBR1L,SCN2B,ESR2,VIRMA,RPL10,ZNF622,SEC62,CFTR,DUSP22,ATG16L1,MTX2,PIP4P2,EIF2B3,EXOSC4,NUBP2,CD40,BAP1,PML,FBXW7 |
| 1.769e-03 | -6.34 | CNDP2 (carnosine dipeptidase 2) | protein interactions | 55748 | 129 | 52 | 19454 | 5460 |
SERPINH1,CCT2,CKB,ATP5F1A,USP14,AR,LDHB,PSMA4,LDHA,GDPGP1,ANAPC2,CCNF,GSTO2,CNDP2,ARCN1,LMNA,RPA2,CAPN1,ZDHHC17,NUCKS1,NMRAL1,LCP1,RPA3,UBFD1,DNAJC7,RPL23,SMAD4,AGR2,XPO1,COPS5,GAPDH,MOV10,PDIA3,G6PD,RAB1B,HNRNPL,RAP1B,RPLP2,SYNCRIP,EZH2,RAB4A,NHERF1,EEF2,UBR7,MVD,VTA1,RAB8B,CAPZA1,CSE1L,HSPD1,TRIP4,PABPC1 |
| 1.769e-03 | -6.34 | SCD (stearoyl-CoA desaturase) | protein interactions | 6319 | 129 | 52 | 19454 | 5460 |
RB1CC1,RHOG,AGR2,SNRNP70,ESYT1,ATG7,MARCHF5,TLCD4,HSD17B11,RAC2,CYB5A,TES,RPN1,MAP1LC3B,DNAJC25,PPP2R1A,CCDC47,PSEN1,RIGI,ARHGAP15,SLC7A14,GJB1,KRAS,MFSD14B,ATP1A1,SPOP,CYB561,CGRRF1,OST4,SCN3B,CUL3,ESR2,MGST3,RETREG3,CYBC1,SEC61B,RPS3,UQCRC2,SLC25A3,VAPB,SSR1,STOM,RND2,SEC62,PGRMC1,TIMMDC1,RNF5,CLEC12B,RNF113A,RTN4,TMX2,JAGN1 |
| 1.774e-03 | -6.33 | negative regulation of transferase activity | biological process | GO:0051348 | 213 | 83 | 18204 | 5365 |
PKIA,PYCARD,THY1,DUSP10,STK38,TRIM27,HEXIM1,SPRY1,SOCS4,RPS7,INPP5K,AKT1,PTPN1,SRC,BAG2,ERRFI1,HEXIM2,RGS2,IL1B,CORO1C,PTPN22,PTPRQ,PPIA,GNAQ,MIR34A,DUSP1,HSPB1,PRDX3,DUSP19,MIR15A,PDCD4,RTRAF,GSTP1,HYAL2,DUSP3,MIR24-1,CHP1,DUSP22,IFNG,DBNDD1,CAMK2N1,TAF7,ADIPOQ,YWHAG,SPRED1,BANF1,TRIB1,SLC8A1,RPL23,PAQR3,LILRB4,MIR218-1,PPARG,PAK2,SFN,CAMK2N2,MIR711,PPP2R5A,GADD45A,CBL,PKIG,MIR20A,CDKN1B,GSKIP,EIF4A2,SOCS5,DEFB114,CEP85,RB1,UBASH3B,CAV3,CDK5RAP3,TESK1,GSK3A,PKIB,CDKN1A,LRP6,MACROH2A1,MAD2L2,PTEN,MAD2L1,TSG101,CAV1 |
| 1.775e-03 | -6.33 | TRAPPC11 (trafficking protein particle complex subunit 11) | protein interactions | 60684 | 94 | 40 | 19454 | 5460 |
YWHAB,RIT1,TRAPPC4,HNRNPD,ATG3,TRAPPC2L,YWHAZ,RACGAP1,YWHAG,ATG7,ARL6IP6,YWHAH,ATG9A,RAB2A,VIRMA,HSP90AB1,TRAPPC6B,POLE3,RAB1B,SPPL3,CAND1,KRT8,TRAPPC10,ALB,TRAPPC3,CMBL,UBE2M,TRAPPC13,KLC2,TRAPPC3L,CTBP1,CNPY3,FUT8,BET1,TP53,PTAR1,KRAS,IGF1R,SLC39A9,TRAPPC1 |
| 1.775e-03 | -6.33 | BEND7 (BEN domain containing 7) | protein interactions | 222389 | 94 | 40 | 19454 | 5460 |
POLR3GL,CSNK2A1,MORF4L1,PBLD,ZCCHC10,PPIG,KPNA1,NOL12,NIF3L1,PSMB1,PRKRA,TRIM27,GYS1,SCNM1,RPS3,EAF2,RPL22,GADD45G,CIB3,RBBP4,LYAR,ZNF622,PLEKHF2,MAGOHB,THAP1,TNPO2,LMO3,UBL5,MFAP1,SDCBP,NKAPD1,RAB29,EIF1AD,DVL2,ANP32B,CDCA7L,RPL4,TRIM26,NAP1L3,DGCR8 |
| 1.775e-03 | -6.33 | KIAA1217 (KIAA1217) | protein interactions | 56243 | 94 | 40 | 19454 | 5460 |
ZYX,RPA3,RINT1,LIPA,KRAS,KDM1A,FXR2,WASF3,FLOT1,TBK1,RAF1,ATG16L1,SOX2,TRAF2,RAB4A,RND3,CTNNA1,GJA1,HNRNPL,SIAH1,CNTROB,ESR2,VIRMA,HSBP1,TRAF1,DYRK1A,MYC,NDC80,BTF3,YWHAH,XPO1,PPP1CC,CTNNB1,AR,GCC1,BICD2,ZDHHC15,EXOC8,HSPB1,MAPRE1 |
| 1.775e-03 | -6.33 | TRAF3IP1 (TRAF3 interacting protein 1) | protein interactions | 26146 | 94 | 40 | 19454 | 5460 |
TAB2,IFT22,TAF10,DMAP1,IFT57,DISC1,EEF1A1,ACTN4,BORCS6,CCNA2,TBK1,SPTBN1,SGF29,SMC4,SSNA1,HSPA8,BLOC1S2,PGK1,LCA5,HSP90AA1,MAP4,CKB,UBXN10,TRAF6,RPL24,H2BC9,SNAP91,EXOC1,KXD1,IFT25,CACYBP,HSP90AB1,CDC5L,RPL7,TUBB,MAPRE2,ACTB,S100A8,IFT172,PHB1 |
| 1.783e-03 | -6.33 | CBR1 (carbonyl reductase 1) | protein interactions | 873 | 132 | 53 | 19454 | 5460 |
AGPAT1,UPK1A,CBL,DDRGK1,COPS5,WWP2,TMEM208,NCBP2,STX6,MARCHF4,NRSN1,CCR1,FAF2,SOX2,B3GNT2,RBM12,TOP3B,IMMP2L,RAD21,PAX6,SLC25A32,RPS24,HAPSTR1,CBR3,UBE2H,MARCHF3,YWHAZ,CGRRF1,BRCA1,SPOP,ATG101,MYC,PARL,SEC61B,ZBTB18,PIH1D1,UBE2M,RNF103,RPA2,CDK7,CFTR,MYH1,TXNL4A,PRKAB1,SSBP2,SLC37A4,STAU1,UFL1,PSMA3,HSPA8,PML,BAP1,RPA3 |
| 1.783e-03 | -6.33 | GHITM (growth hormone inducible transmembrane protein) | protein interactions | 27069 | 132 | 53 | 19454 | 5460 |
IZUMO1,CA14,NRN1,AGPAT5,TP53,FAM162A,PDE2A,MDC1,SAR1B,CHCHD2,CD1B,DNAJC30,EFNB1,EMC2,LRRN4CL,NDUFA4,SFXN1,CDH13,UQCC6,HM13,PIANP,MPG,DDRGK1,PTPN5,ILVBL,TOR1B,RAMP3,SLC25A12,RAP1B,THY1,PTPN1,CCDC127,ARL15,RPA2,LMNA,LRRN1,GPR35,TPRA1,NT5C3A,CCR4,HSPA5,SLC7A1,VIPR1,RPA3,RIOK2,PMPCA,GPR37,COPE,B4GALT3,SYNGR1,SARM1,S1PR4,DPEP1 |
| 1.783e-03 | -6.33 | DDR2 (discoidin domain receptor tyrosine kinase 2) | protein interactions | 4921 | 132 | 53 | 19454 | 5460 |
VAPB,CLU,COL3A1,RAB9A,HADHA,DNAJC3,INPPL1,SERPINH1,VMP1,NTRK3,HSP90AA1,RHOB,CHORDC1,CKB,SLC25A1,VIRMA,SRC,TECR,EPCAM,MACROH2A1,SEC61A1,AP2M1,CTNNA1,STX12,STIM1,TFRC,RPN1,MACO1,RFC3,FKBP8,DMPK,DHX9,HSD17B10,ABCE1,NDUFA4,DDR1,SLC25A5,OSBPL8,TST,FKBP4,SHC1,SLC2A1,CTNNB1,BAZ1B,HSP90AB1,MSMO1,PTP4A3,SEC23A,SSBP1,PTPN1,SRPRA,WDR6,HACD3 |
| 1.783e-03 | -6.33 | COPZ1 (COPI coat complex subunit zeta 1) | protein interactions | 22818 | 132 | 53 | 19454 | 5460 |
EPHA4,KRAS,ARF4,SMIM11,SACM1L,RIGI,SCYL2,SEPTIN7,CDK5,SH3GLB1,E2F4,DUSP1,TMED9,ARL6IP5,ARF6,FZR1,LMAN1,EGLN3,PRCC,DRG1,XPO1,COPS5,GOLPH3L,FBXW7,STAU1,PPM1G,RPA3,BAP1,APMAP,SF3B1,HSPA8,TNFAIP1,RPA2,ARCN1,CNDP2,COPE,PPP1R10,UGT1A1,ESR2,APEX1,CCNF,DLST,SF3B4,COPZ2,CHORDC1,BICD2,CUL3,SUB1,PTPN11,PSMD1,MCM4,BAG3,RACGAP1 |
| 1.783e-03 | -6.33 | DCAF11 (DDB1 and CUL4 associated factor 11) | protein interactions | 80344 | 132 | 53 | 19454 | 5460 |
CEP85,GSTK1,LDHB,CUL3,COPS7A,ST13,PSMD1,CCT2,PFDN6,ANAPC4,COP1,TBCCD1,CCNF,PPP2R5E,PTEN,CDKN1A,ELP3,CTBP1,FKBP1A,UBE2M,SIRT7,PRIM2,CCDC186,PFDN5,COPS5,AGR2,DRG1,COTL1,AIP,CBFB,AIFM1,COPS2,GNPAT,TCP1,DCUN1D1,COPS7B,NOB1,CCT7,DBT,CCT5,NFE2L2,TNNI1,AP2S1,PARP11,MLLT11,TFPT,RTCB,RUVBL2,TRIM63,TTC4,ETFA,NEDD8,COPS4 |
| 1.783e-03 | -6.33 | purine ribonucleoside triphosphate metabolic process | biological process | GO:0009205 | 175 | 70 | 18204 | 5365 |
NME1,NDUFB10,ATP5F1A,NDUFAB1,NDUFS8,NDUFA1,LDHA,HSPA8,OLA1,HTR2A,PGAM1,ENO1,GTPBP1,NDUFB7,NDUFA5,ATP5MC3,NDUFA12,ATP5MK,COX11,NME2,PFKFB2,FKRP,ENO2,UQCC3,ATP5PB,STOML2,DNAJC30,UCP2,RAB23,ATP5MG,GNAI3,NDUFS2,ATP5F1B,IER3,NDUFV2,NDUFB6,PGM1,ATP5PD,NUDT2,NUDT5,SDHC,RAN,MFN1,NDUFC2,OGDHL,ATP5PF,NDUFS6,AK5,ATP1B1,PGK1,ATP5PO,SDHB,LIPA,ATP1A2,NDUFB8,BPGM,NDUFA2,ATP6V1A,NDUFB4,CLPX,AK2,GAPDH,NME4,NDUFB5,ATP5F1D,ATP5MC1,NDUFS3,ATP5F1E,AK3,BAD |
| 1.784e-03 | -6.33 | NOTCH4 (notch receptor 4) | protein interactions | 4855 | 17 | 11 | 19454 | 5460 |
EGFL7,ELOC,TP53,PSEN2,SMAD3,MDM2,SMAD2,PSEN1,RBPJ,FBXW7,SMAD4 |
| 1.784e-03 | -6.33 | SPEG (striated muscle enriched protein kinase) | protein interactions | 10290 | 17 | 11 | 19454 | 5460 |
YWHAZ,VAPB,YWHAB,ATG16L1,MYC,TOP3B,YWHAG,YWHAH,FBXO22,FZR1,PICK1 |
| 1.784e-03 | -6.33 | SMAD1 (SMAD family member 1) | protein interactions | 4086 | 223 | 83 | 19454 | 5460 |
TLR2,RAB30,SF3B1,SQSTM1,RAP2A,EP300,BMPR1A,ARHGEF6,PIAS1,FBXO30,CXXC1,UCHL3,MLH3,FBXW7,ELP3,CDK7,ACTL6A,WDR77,RASL12,UBA52,NOTCH2,CCND1,LEMD3,LMNA,BTG2,WWP1,GP9,ING2,STUB1,RAN,CTNNA1,SMURF1,FRZB,SMAD5,IRF2BP1,MED17,PSMD1,ZCCHC12,RUNX1,SMARCE1,AR,CREBBP,MED22,OAZ1,STK11,SMAD2,EWSR1,OAZ3,BCL7B,SNIP1,RPS27A,NAT9,PAX6,RAB3B,MAP2K3,SMAD1,PREB,TP53,MED9,TAPT1,HBP1,HGS,STARD13,CDK8,NKX3-2,EZH2,NFE2L2,ACVR1,RAB6B,ARL4D,RAC2,AKR1B1,SMAD3,PSMB4,CDK9,XPO1,SUV39H1,INPP4A,MED4,USP15,RHOG,SMAD4,SNRNP70 |
| 1.785e-03 | -6.33 | amide binding | molecular function | GO:0033218 | 254 | 98 | 18094 | 5411 |
CLU,PPWD1,LILRB1,LANCL1,LDLR,RXFP2,PC,TLR6,PFDN4,TLR2,NPR2,NLGN1,ITGA2,MTHFS,GHR,FOLR1,ITM2B,FKBP4,VIPR1,PFDN6,PFDN5,CD1A,CD1C,PRNP,FCGR2B,ATP1A3,CST3,PFDN1,VDAC1,TLR4,PIK3R1,PPIB,GSTM2,FZD4,PPP3CA,FKBP1B,IDE,ACBD7,GNMT,PPIA,FKBP1A,CLSTN3,PPIH,AGER,PHB2,CD1D,CD36,HADHA,PGRMC1,GRIA1,TLR1,RAMP3,MAP1LC3B,GLTP,TGFB2,GSTM4,GRIA2,FZD6,APBB3,TLR10,CD1B,GPRASP2,PPID,ADRB2,IZUMO1R,FKBP10,MGST2,CRYAB,IGF1R,CPTP,BACE1,PPIC,CMKLR2,MMACHC,CD1E,CLIP3,PTGES,C2CD2L,GSTM3,FKBP2,PPIF,ACBD6,OXTR,CLN8,TYMS,CRHR1,ACHE,FOLR2,EPHA4,PFDN2,ACVR1,PPIG,CHRNA7,ITM2A,VDAC2,PLEKHA8,CRHBP,PICALM |
| 1.788e-03 | -6.33 | PHB | smart domains | SM00244 | 11 | 8 | 9717 | 2575 |
STOM,STOML3,PHB2,STOML2,ERLIN2,PHB1,FLOT1,ERLIN1 |
| 1.798e-03 | -6.32 | PCGF6 (polycomb group ring finger 6) | protein interactions | 84108 | 168 | 65 | 19454 | 5460 |
RB1,EED,CCT7,EIF2B2,TCP1,CSNK2A1,USP2,IFI16,CDK12,RING1,CCT8,MAGEC2,RERE,PCGF6,PAX6,TRIM63,CBX7,PCGF3,H3C1,ELF1,TULP3,TIMM8A,EGR2,CCT5,E2F4,MAX,PHC1,ZNF526,CHAMP1,CBX3,ZMYM2,CSNK2B,LURAP1,ELK3,ZBTB33,PNMA1,CBX5,LRIF1,KANSL3,MYC,DSN1,UBE2H,HSP90AA1,TFDP2,CCT2,YAF2,PCGF2,MIS12,HSPB2,ZKSCAN1,CORO6,FTL,SKP1,TRIM52,STAU1,UBE2D3,GDPD3,KLF12,ELP3,CDK7,TIMM13,E2F6,ADNP,KLF3,MXD1 |
| 1.803e-03 | -6.32 | CNOT10 (CCR4-NOT transcription complex subunit 10) | protein interactions | 25904 | 138 | 55 | 19454 | 5460 |
NUP153,TOP3B,YTHDF2,TNRC6C,POLR2C,GPBP1L1,CAPZA2,ZC3H7A,GARRE1,LSM14A,CNOT6L,PTGES3,CAPZA1,G3BP1,CNOT7,CHMP1B,CNOT8,CPEB1,CNOT2,MED4,FUBP3,EEF1AKMT3,DUSP6,CNTROB,EGLN3,PAIP1,PRNP,ATG16L1,TANK,RPA2,SQSTM1,RPA3,G3BP2,FXR2,YTHDF1,STAU1,CDC16,CEP85,PAIP2,UHMK1,MAPRE1,UBE2H,RIT1,RC3H2,GADD45B,ANAPC2,CTTN,CNOT6,BTG3,DYRK1A,RPL10,PRRC2A,ESR2,STAT1,FANCD2OS |
| 1.803e-03 | -6.32 | RPS6KA5 (ribosomal protein S6 kinase A5) | protein interactions | 9252 | 138 | 55 | 19454 | 5460 |
CDC42,H1-5,PGRMC1,UBE2M,RPA2,ATP5PO,HSPB2,EP300,RPA3,ATF1,GGH,AKT1,AKT3,CREBBP,HSP90AA1,CRMP1,STK11,PFDN6,H1-1,CHCHD4,YWHAZ,CSNK2B,CREB1,BAD,DDAH2,VIRMA,ERH,STAT1,DYNLL1,PSMD6,ATP5PB,SMARCB1,EZH2,MRPS18B,CLPB,H2AC25,MAP1B,NDUFA4,PSMD12,MRPS17,PTGES3,KRAS,LAMP3,GPRASP2,MOV10,NFKB1,MAPK4,FAM174A,AK2,COQ8A,SIN3A,EEF1AKMT3,ATP5PD,MRPL24,THOC1 |
| 1.803e-03 | -6.32 | PFN2 (profilin 2) | protein interactions | 5217 | 138 | 55 | 19454 | 5460 |
EEF1A1,EZH2,NGB,IK,GEMIN7,SNRPE,NAE1,PSME1,G3BP1,TRIM37,ROCK2,CAPZA1,SMN1,SNRNP70,NDUFB8,TSNAX,PTPN1,SIN3A,ACTA2,PSMB1,RAC2,RPS10,EGLN3,DHX15,DUSP14,RNF146,PIH1D1,BIRC2,HSPA8,PPIH,DDX5,GTF2I,HNRNPC,PSMA4,RNF40,HMGCS1,SNTA1,MYO6,RHOB,GEMIN8,IVNS1ABP,COP1,UBE2H,CCNF,SESTD1,EIF3K,DLST,SNRPD2,SGTA,ACTB,ROCK1,NCKAP1,ESR2,UBA3,MAD2L2 |
| 1.805e-03 | -6.32 | EIF3K (eukaryotic translation initiation factor 3 subunit K) | protein interactions | 27335 | 165 | 64 | 19454 | 5460 |
PML,BAP1,RPA3,CFDP1,RAB5A,RPL4,EIF1B,UFL1,G3BP2,CCND3,EIF4E,TANK,EIF3J,CFTR,EMC9,RPA2,UBE2M,UTP15,EIF4B,HEXIM1,METAP2,PSPC1,CCNF,SEC61B,EIF4A2,APEX1,ESR2,VIRMA,CUL3,FAS,EIF3G,UBE2H,RPS26,ICAM1,PDCD4,METTL18,G3BP1,EIF4EBP2,EIF3E,PSMD12,E2F4,DNAJC2,CHMP4C,EZH2,SRP72,EIF2B2,DYNC1I2,TOP1,EIF2B5,RPS10,FZR1,RPS16,RBM42,WWP2,IFI16,ENY2,EIF3D,CD81,CSNK2A1,COPS5,SPP1,DRG1,HNRNPD,DDX1 |
| 1.805e-03 | -6.32 | H2BC15 (H2B clustered histone 15) | protein interactions | 8341 | 77 | 34 | 19454 | 5460 |
CCNF,TMA7,CMTR1,MACROH2A1,SPPL3,BCCIP,VIRMA,RPL22,MYC,WWP2,BTF3,CD81,DRAP1,TMEM196,PSMD14,H2AC4,ICAM1,HNRNPD,MAP1B,NKAPD1,CWF19L1,EWSR1,PRKCB,SREK1IP1,SQSTM1,H1-6,UCHL3,TRIM37,MEPCE,RAF1,PRR13,ELK4,HEXIM1,MACROH2A2 |
| 1.805e-03 | -6.32 | FAM118B (family with sequence similarity 118 member B) | protein interactions | 79607 | 77 | 34 | 19454 | 5460 |
NDUFA4,OSTM1,EPHA4,NPTN,CD80,SSRP1,ING5,SUMO1,TOMM22,SDCBP,VAPB,LMNA,CTDSP1,MED31,CYRIB,TMSB4X,SCN2B,DFFA,CTSB,RASGRP2,FAM118B,FAM20C,FAM174A,NDC80,SPRED1,LAMP2,CEP70,TOMM40,SHC1,FAS,ARMT1,ZMPSTE24,PDCD10,ICAM1 |
| 1.805e-03 | -6.32 | SP3 (Sp3 transcription factor) | protein interactions | 6670 | 77 | 34 | 19454 | 5460 |
ATP5PB,SP4,FNDC8,SUMO1,TP53,ABCB1,PML,EP300,PIAS1,TNFSF10,CREBBP,AKT1,SUB1,CUL3,ELOC,SNRPB,PPP1CC,MECP2,SP1,VEGFA,NKX3-1,MAP1LC3A,SEC23A,LDLR,PHF21A,UBE2I,RPS20,RB1,RBBP4,B4GALT4,TCP1,GABPA,CIB3,ESR2 |
| 1.805e-03 | -6.32 | TNS3 (tensin 3) | protein interactions | 64759 | 77 | 34 | 19454 | 5460 |
HECTD1,MET,CFTR,CCT5,ATG16L1,RAF1,STAU1,KRAS,HUWE1,EPHA4,KIT,RHOU,HSPD1,YWHAB,XPO1,YWHAG,YWHAH,PYCR2,SFN,RBM17,MYC,CSK,MOV10,CCT7,ESR2,SRPK2,VIRMA,MAT2B,UMPS,RAC2,GANAB,GSK3A,ENO1,GAB1 |
| 1.809e-03 | -6.32 | PLEKHM3 (pleckstrin homology domain containing M3) | protein interactions | 389072 | 24 | 14 | 19454 | 5460 |
RAB9A,VIRMA,RMND1,YWHAH,DDX39A,LAMP3,YWHAG,MGAT5B,LAMP2,CUL3,YWHAB,LAMTOR1,ENDOD1,YWHAZ |
| 1.809e-03 | -6.32 | MEA1 (male-enhanced antigen 1) | protein interactions | 4201 | 24 | 14 | 19454 | 5460 |
ZER1,RAD23B,AP2A1,ARMCX3,NUP153,IFT25,DPY30,MARCHF5,RAD21,VKORC1L1,AP1M1,PPAT,IGBP1,AP2M1 |
| 1.809e-03 | -6.32 | KCNIP1 (potassium voltage-gated channel interacting protein 1) | protein interactions | 30820 | 24 | 14 | 19454 | 5460 |
TBC1D25,ATRAID,CTXN1,KCNIP2,NIF3L1,SPP1,IL6ST,KCND3,LITAF,SOD3,OR14J1,SPRED2,KCND2,APMAP |
| 1.809e-03 | -6.32 | Myo9b (myosin IXb) | protein interactions | 25486 | 24 | 14 | 19454 | 5460 |
PSMA2,PSMA1,TECR,UNC45A,ARF1,PSMB4,PSMB5,HAX1,SLC25A24,CALU,PSMB2,TP53,LDHB,CDC42 |
| 1.809e-03 | -6.32 | SLC5A8 (solute carrier family 5 member 8) | protein interactions | 160728 | 24 | 14 | 19454 | 5460 |
CAV1,LPCAT3,PTP4A3,DAD1,PXMP2,RAB3B,SLC25A23,GPR89A,ELOVL4,SMAP2,TMEM11,LMNA,SLC25A46,TSPO |
| 1.809e-03 | -6.32 | ZNF19 (zinc finger protein 19) | protein interactions | 7567 | 24 | 14 | 19454 | 5460 |
LMO2,NDUFAB1,RFC5,HOMER3,SCNM1,CDR2L,CINP,ATPAF2,CSNK2B,MAGOHB,BCCIP,AP1M1,STX11,CIB3 |
| 1.810e-03 | -6.31 | FKBP7 (FKBP prolyl isomerase 7) | protein interactions | 51661 | 141 | 56 | 19454 | 5460 |
RPRM,TMEM14A,IER3,SNX1,TSPO2,TMEM97,CNIH1,SLC38A7,VSTM4,CD81,GSTO1,POU5F1,ADGRE2,STX8,RUSF1,ATP5PF,HINT1,TMEM147,LCN9,MYORG,SLC7A14,ERLEC1,ADIPOQ,TF,AP1M1,PLPP6,SELENOK,YIPF4,PPIF,UBIAD1,CTSA,OXNAD1,CYB5B,IRF2,CDIPT,PLP1,ENO1,ENO2,SNX12,SGTA,TMEM108,TMEM229B,TXNDC12,TECR,CYB561D2,PRMT6,FGFBP2,SOD1,TTR,STX7,BET1,TRAM1L1,PLP2,CFTR,CARHSP1,FAM3C |
| 1.811e-03 | -6.31 | KLRC1 (killer cell lectin like receptor C1) | protein interactions | 3821 | 162 | 63 | 19454 | 5460 |
ATXN10,VTI1B,CD151,RAB39B,PXYLP1,TSPO2,CXCL14,DNM2,ACSL4,STARD3NL,AGPAT1,BTN2A2,C1GALT1C1,PMP22,FAM20B,CLDN11,CDK20,B4GALT7,CLEC7A,BACE1,RNF167,C1QL1,CHST10,GALNT12,ATP6V0B,SFTPC,TMEM182,KLRC2,OTULIN,SYNGR3,ITGB5,NETO2,LGR4,AGPAT5,DIPK1A,METTL15,NLGN2,CLRN2,TUBA1B,PLP1,AMIGO1,LRP12,FZD6,B4GALT1,CGRRF1,ATP1A3,VMP1,GRID1,GJB2,PTPN11,VAMP5,VEZT,AKT1,RHOBTB3,LARGE1,LRP10,CXCR4,EMP3,TTI2,CTXN3,HYAL2,KLRD1,GLRB |
| 1.811e-03 | -6.31 | FLNB (filamin B) | protein interactions | 2317 | 276 | 100 | 19454 | 5460 |
RAN,PHF21A,PSMD6,CUL2,CUL3,MYC,UFD1,BTF3,PSMD14,BRCA1,VMP1,DDX5,DCTN3,NUP50,TXNL1,HSPA8,GPC1,HNRNPA0,PRDX3,TSHR,PPP1CB,RNF7,PAK2,PIH1D1,RTF2,EIF4B,SUMO2,HNRNPL,DHX15,PSMD3,GSTM3,XPO1,AGR2,HSPB1,MED4,CCT8,PABPC1,NUDT5,TRIM37,G3BP1,RAD21,HNRNPDL,PSMD12,ISG15,CHMP4C,PLS3,EZH2,CTTN,CCNF,PTEN,PHAX,TXN,RALA,KCTD9,VIRMA,SEC13,MAT2A,USP14,MAPRE1,UBE2H,ATP1A1,CDC73,CSTB,SIRT7,PSEN2,BAP1,RPA3,SEPTIN6,ARFIP1,SQSTM1,KDM1A,HSPA5,MARS1,PIAS1,EIF4E,CFTR,RPA2,HAUS2,UBE2M,RARS1,CD274,AIFM1,TES,FZR1,CDK9,PLEKHO1,KARS1,HDAC6,MAP4,RAB1A,ABCE1,CAMK2G,MDC1,RNF20,PSEN1,TP53,EEF1A1,CAPZA2,TFCP2,NUPR1 |
| 1.814e-03 | -6.31 | regulation of cell cycle | biological process | GO:0051726 | 1120 | 374 | 18204 | 5365 |
NLE1,PAFAH1B1,GNB1L,BIRC5,DTL,WDR12,MIR873,CDC23,TCIM,MIR15A,CDK20,SMARCA5,TAS1R2,TRIM35,HEXIM1,PHB2,TRIM21,LEP,MIR137,FBXO7,PPM1G,NUDT16,RRM1,SMARCB1,NDC80,NF2,MIR29A,CEP85,NR2E1,CUL3,CDK17,IRF1,AFAP1L2,INSM2,TRNP1,CCNB1,CGRRF1,NBN,XPO1,WEE2,TRIM32,MAGEA4,TMOD3,SERTAD1,DUSP1,BIRC2,RINT1,NUF2,ANAPC13,FBXW7,NKX3-1,POLDIP2,SGF29,STK11,CCAR2,MAP2K6,NPPC,NHERF1,CCL2,NUP62,PML,DYNLT3,DCUN1D3,MIR16-1,CACNB4,CRADD,TERT,UBXN2B,NEK2,CCNH,CCNF,GADD45A,MIR222,NAE1,CDK4,PLAGL1,RNF40,UBE2E2,MX2,TP53INP1,BAX,EIF4E,USP2,TOM1L1,BTG1,ASPM,CETN2,GADD45G,CHMP1A,JUNB,AKT2,ACTL6A,JUN,ATXN10,UHMK1,AURKAIP1,TAS2R13,DMAP1,MIR10A,MTA3,PRNP,SMARCE1,DAPK3,MAD2L2,CHMP2A,SIN3A,WNT10B,RPRM,BAP1,CHMP2B,BABAM1,NCAPG2,RMI2,PLCB1,SMARCD3,HDAC3,UBA3,MAEA,RGCC,UBE2B,MSX2,SFN,ANAPC2,CDKN3,MIR21,CDC73,INHA,CKS2,MIR519D,ECD,PPP1R10,IGF1,DR1,TTL,CALR,OVOL1,CTNNB1,NPR2,BAK1,CCNI,CCND3,RANBP1,GMNN,CDC7,FAM107A,AKT1,NOP53,IL1B,PRMT5,RPL26,DRD3,INO80E,BCL2L1,CDKL2,E4F1,MORF4L1,PTEN,MCPH1,TSG101,TTI2,LRP6,CDK5RAP3,CRY1,PRKCE,AATF,RIOK2,BUB3,CTDSP1,PSMG2,CCND1,CDK12,MIR221,BRINP1,CDC26,SDCBP,ACTL6B,MIR133B,CCNY,MDM2,LCMT1,ERCC3,TP53,CDK2AP2,KIF3B,VPS72,NEK7,VPS4A,MIR34A,TMEM14B,ANAPC16,FGFR1,CHORDC1,VASH1,MIR26B,RAD1,CHMP1B,BRINP2,HSPA8,KLF4,CKS1B,CEP97,MIR590,PTPN11,TFPT,JADE1,CDK6,DDIT3,MNAT1,RAD21,SLC6A4,MIR638,MIR195,YTHDF2,TPRA1,CCSAP,EZH2,RNF20,KLHL22,BTG2,MIR193A,CDKN1B,SUV39H1,MIR711,GPNMB,PPP2R1A,CHMP5,UFL1,RACGAP1,CHMP4C,MIR503,MLF1,CCNA2,PSME2,RPL23,ACTB,DDRGK1,TNF,CRLF3,ROCK2,IL10,CDK8,CDKN2C,MRGPRX2,MSX1,FBXO31,NEK9,RUVBL1,RPA2,RAB11A,MIR495,BCL7B,INO80C,KLHL9,BCL6,TOPBP1,NSFL1C,HEXIM2,CDK5,BCCIP,HINFP,PCLAF,PKIA,HRAS,RHOB,PSMD10,CDK9,SH3GLB1,CDKN1A,USP16,H2AX,ZNF655,MIR424,RB1,IK,PRKCA,TFDP2,MIR214,ACVR1,PSME1,ARF6,AIF1,GAS2,PLSCR1,BCL7C,ZNF207,CDC16,MYC,ANAPC4,IER3,SFRP1,IGF1R,CDC42,FZR1,CDC20,NUPR1,TRIM36,PSRC1,CDK1,LILRB1,BTN2A2,CDK5R1,CTDSP2,MEPCE,RBBP8,ZBTB17,TNKS,PRCC,MEAF6,CDKN2D,MAD2L1BP,PIM2,HSP90AB1,CD28,ANAPC15,RUVBL2,THAP1,HTRA2,MDC1,MIR208A,ZMPSTE24,BRCA1,GADD45B,LSM10,RPS27L,SRPK2,SMC4,IL1A,DUSP3,TGFB2,FGF10,SPC24,ADAMTS1,RPRD1B,TRIM37,SOX2,RPA3,FEM1B,PKP4,VPS4B,CCNQ,PIWIL2,RNF167,TOM1L2,PROX1,ATP2B4,NABP1,MIR29C,MAD2L1,CDC5L,ANAPC11,ING5,CAV2,MACROH2A1,PRPF19,PAGR1,DRG1,CTBP1,PRMT2,COPS5,BTG3,DIRAS3,HBP1,CSNK2A1,TADA3,FZD3,FEN1,SOX9,RHEB,BAZ1B,BECN1,BRINP3,CDK7,CYP1A1,DLG1 |
| 1.814e-03 | -6.31 | Mitochondrial_sb/sol_carrier | interpro domains | IPR018108 | 53 | 26 | 18521 | 5414 |
SLC25A17,SLC25A21,SLC25A26,SLC25A14,SLC25A24,SLC25A20,SLC25A46,SLC25A51,SLC25A5,UCP2,SLC25A27,SLC25A39,SLC25A12,SLC25A45,SLC25A23,SLC25A3,SLC25A10,SLC25A11,SLC25A28,SLC25A1,SLC25A44,SLC25A4,SLC25A31,SLC25A32,SLC25A42,MTCH2 |
| 1.814e-03 | -6.31 | Mt_carrier_dom_sf | interpro domains | IPR023395 | 53 | 26 | 18521 | 5414 |
SLC25A11,SLC25A10,SLC25A1,SLC25A28,SLC25A44,SLC25A4,SLC25A32,SLC25A31,SLC25A42,MTCH2,SLC25A21,SLC25A17,SLC25A26,SLC25A14,SLC25A20,SLC25A24,SLC25A46,SLC25A5,SLC25A51,UCP2,SLC25A12,SLC25A39,SLC25A27,SLC25A3,SLC25A45,SLC25A23 |
| 1.815e-03 | -6.31 | POLR1C (RNA polymerase I and III subunit C) | protein interactions | 9533 | 298 | 107 | 19454 | 5460 |
MYD88,DNAAF10,KPNA2,PTGES3,SMN1,PDRG1,TAF1D,RPAP2,SPSB3,TNNI1,HOXD12,SPRY1,NUPR1,POLR2G,POLR2I,FZR1,NOP9,MRPS23,DKC1,GMPPB,POLR3GL,CSNK2A1,TIAM1,ZNF688,DNAJC7,TNFAIP1,FBXW7,NME4,CLU,POLR1H,GRPEL1,CPSF4,POLR1D,RPRD1B,TFIP11,CCNF,ZNF655,POLR3H,TRIM27,SNX3,RPL13A,BCCIP,SMARCA5,NDUFB10,CFL1,GPRASP3,SPMIP10,NIF3L1,NRP1,RTCB,RUVBL2,RPAP3,ROCK2,RUVBL1,ZBED1,KRAS,PSMA1,POLDIP3,E2F4,TRMT1L,NME1,CHMP4C,MOB3C,POLR2D,POLR2C,POLR2L,RPRD1A,POLR3F,HSP90AB1,EGLN3,CGGBP1,IFI16,GAS8,CTNNB1,MAP3K14,DDX1,EP300,HSPA8,HSCB,NRBF2,LNX2,PSMB7,PPARG,PIH1D1,GSTO2,ZBTB42,EIF4B,NFKBIB,KRTAP3-1,LMBR1L,AVPI1,POLR2F,POLR3B,TAX1BP1,POLR2B,LRIF1,RRN3,CUL3,MYC,ATG3,WDR20,CIRBP,PFDN6,MAF1,POLR1B,RIT1,PFDN2 |
| 1.815e-03 | -6.31 | FARSA (phenylalanyl-tRNA synthetase subunit alpha) | protein interactions | 2193 | 159 | 62 | 19454 | 5460 |
FZR1,EGLN3,TMPO,CD274,PHB1,FBXO32,KRT8,PSMG2,SLC25A28,PDCD10,TRMT5,WWP2,HDAC6,CTNNB1,DDRGK1,KRAS,PRPS1,MAP1B,POLR2C,RAF1,SOX2,EEF2,PSMD4,IRF2BP1,RPL35,PPP5C,RPL10,MAD2L2,CCNF,LMBR1L,EIF2AK2,PTEN,LAMTOR1,RHOB,RC3H2,PSMD14,UBE2H,RIT1,CUL3,FBXO7,USP14,AR,NF2,UFL1,STAU1,ARHGEF39,COIL,BCL6,RPA3,RAB5A,RNF113A,AKAP1,SQSTM1,RPA2,GRM2,HEXIM1,RPLP0,PIH1D1,ATG16L1,GABRA1,CDC42,CFTR |
| 1.819e-03 | -6.31 | UNC119 (unc-119 lipid binding chaperone) | protein interactions | 9094 | 147 | 58 | 19454 | 5460 |
TOP3B,SERPINB9,MAPK10,UBE2B,TP53I3,CDKN2C,ORAI2,HSPE1,SMN1,SEPHS1,UNC119B,ZNF24,YWHAH,TP53INP1,YWHAG,FXYD6,MPHOSPH6,LRRC57,PPP3CA,CD247,PDE9A,CD4,ARL4D,CETN3,S100A8,RAP1B,MDM2,PDE8A,CFTR,CDKN1A,CDC42,RPA2,ANXA7,CKS2,ARL15,CCL18,MACIR,ZFP64,TTC1,COX17,RNF34,SAT1,HMGB1,KDM1A,BRIX1,CYB561D2,RGL2,RFC5,PSKH1,PAFAH1B3,AVPI1,FKBPL,UBE2I,EIF2S2,ERH,CEP97,LRIF1,GSTM4 |
| 1.820e-03 | -6.31 | PHF6 (PHD finger protein 6) | protein interactions | 84295 | 150 | 59 | 19454 | 5460 |
ZNF263,CSNK1E,RAF1,MAP1LC3B,TULP3,PDHA1,NUPR1,MRFAP1L1,HNRNPA2B1,HAPSTR1,RBBP7,MEPCE,EDEM1,TMA16,DDRGK1,H2AC4,SNRNP70,MAGOH,SRP14,H2AZ1,PHB1,HNRNPL,FZR1,CAND1,LYAR,ZBTB2,CDC42,CPLX2,RPLP0,HNRNPH3,CSNK1A1,ATP5IF1,EMP3,EP300,RNF113A,UFL1,FBXW7,RPL4,STAU1,COIL,MYC,HNRNPC,CUL3,BTF3,ARHGAP21,PCBD1,RC3H2,UBE2H,CCNF,TACO1,CMTR1,ZNF330,RBBP4,SMURF1,DYRK1A,RPL22,RPL10,ESR2,SRPK2 |
| 1.821e-03 | -6.31 | negative regulation of monoatomic ion transport | biological process | GO:0043271 | 132 | 55 | 18204 | 5365 |
FKBP1A,EPO,CLIC2,KCNAB1,CAV1,PPP3R2,MIR200C,NHERF1,PCSK9,PRKCE,FKBP1B,SRI,CRHR1,CAV3,MIR424,MIR448,GPR35,SUMO1,PLN,TLR9,MRLN,MIR208A,GSTO1,MIR212,PPIF,MIR153-1,CNR1,ATP1A2,STC1,HCRT,MIR192,PACSIN3,ISCU,MIR24-1,TCAF2,MIR1-1,SESTD1,MMP9,MIR34A,PPP3CA,MIR30D,VDAC1,TMBIM6,LILRB1,INPP5K,HTR2A,GSTM2,MIR208B,CRBN,CAB39,HECW1,OXSR1,DRD3,TRIM27,ATF4 |
| 1.828e-03 | -6.30 | LSM1 (LSM1 homolog, mRNA degradation associated) | protein interactions | 27257 | 97 | 41 | 19454 | 5460 |
WASL,LSM4,SNRPG,RIGI,BCL6,SMN1,LSM14A,PRPF4,HNRNPA2B1,SNRPA,INPPL1,UBE3A,LSM2,TFCP2,USP39,P3H1,SNRPE,TOP3B,EXOSC8,NDUFAF3,GSTA4,SNRPD3,SNRNP40,LSM5,RAB14,SNRPB2,PSMB5,MPDU1,TRIM24,SNRPD1,SNRPD2,AGR2,SNRNP70,LSM6,GEMIN8,DDX23,HSP90AA1,LSM3,MCCD1,SNRPB,XPO1 |
| 1.828e-03 | -6.30 | PDCD10 (programmed cell death 10) | protein interactions | 11235 | 97 | 41 | 19454 | 5460 |
RPA2,LMNA,METTL14,HEXB,PPME1,CENPM,HEXA,PPP2R1A,EHD1,CNPY3,SNRNP27,UBR7,GTF2E2,HNRNPF,FARSA,DMPK,RPA3,CTTNBP2,NDUFA4,SIKE1,PCNA,STK26,STK24,IVNS1ABP,FGFR1OP2,FAM174A,GAPDH,MAP3K3,CHMP5,CTTNBP2NL,FERMT2,FAM118B,SLMAP,MINAR1,ZBTB2,PPP2CB,TRAF3IP3,CAB39,MOB4,SGTA,ATP6V1A |
| 1.828e-03 | -6.30 | FAM136A (family with sequence similarity 136 member A) | protein interactions | 84908 | 97 | 41 | 19454 | 5460 |
RBFOX2,ATP5PB,DUSP14,NUDCD3,LARP4B,NDUFS6,FAM136A,SNIP1,TIMP3,SFXN1,CLPB,CYBRD1,CHCHD2,YTHDF1,PHB2,MBD3,POLDIP2,RBFOX3,DPY30,NTAQ1,COX10,MRPS16,STN1,LMNB1,AIFM1,ACOX1,SPMIP9,NKX3-1,ENO1,COX4I1,CYB5R3,PSMB1,DNAJB9,PAQR4,IDE,ATP5PD,SRC,COX14,NUP35,PLGRKT,PARL |
| 1.830e-03 | -6.30 | SEC31A (SEC31 homolog A, COPII coat complex component) | protein interactions | 22872 | 217 | 81 | 19454 | 5460 |
TP53,B3GNT2,TBK1,FURIN,CYB5B,KLHL12,TRAPPC13,CHMP4C,PLS3,EZH2,IGF1R,HSD17B10,RTCB,SLC39A7,BHLHE40,LSM14A,PSME1,SAR1B,TFG,PFDN1,NOC4L,XPO1,HNRNPA1,RAB5C,MOV10,ATP6V1D,HNRNPD,TRAPPC2L,SEC23A,TRAPPC10,EED,GJA1,COMT,PSME2,CAV1,HSP90AB1,DHX15,CDK9,POLE3,PRNP,RAB1B,CD2AP,BET1,ATP6V1C1,PIH1D1,ACACA,UBE2M,FGFR1,CTBP1,RPA2,EP300,NUP50,HSPA8,SLC39A9,BAP1,RPA3,USP8,STAU1,SLC30A5,SEC13,GFUS,CUL3,MYC,ARMT1,IGF2BP1,NTRK3,BRCA1,MSN,GNPDA1,ALG2,ENO2,LMBR1L,OPTN,ARF1,CCNF,APEX1,VIRMA,ESR2,IDE,GRPEL2,RAB14 |
| 1.835e-03 | -6.30 | maternal placenta development | biological process | GO:0001893 | 35 | 19 | 18204 | 5365 |
JUNB,STC1,GHRL,TCF23,CYP27B1,AKT1,PARP2,SPP1,TPPP3,NDP,CTSB,GJB2,STOX2,BMPR2,VDR,PTN,LDOC1,DEDD,PRDX3 |
| 1.835e-03 | -6.30 | response to copper ion | biological process | GO:0046688 | 35 | 19 | 18204 | 5365 |
CDK1,SOD3,IL1A,AQP2,NFE2L2,MT1A,TFRC,MT1E,MT3,CYP1A1,AANAT,MAP1LC3A,BACE1,BECN1,MT1M,MT1X,MT2A,ATP5F1D,PRNP |
| 1.836e-03 | -6.30 | NCOR2 (nuclear receptor corepressor 2) | protein interactions | 9612 | 248 | 91 | 19454 | 5460 |
NFKB1,IRF4,NR4A2,FOXP1,MYBL2,EGR2,PPARA,NFE2L2,SGIP1,ZSCAN5A,RIGI,CSK,AKT1,RUNX1,AR,INPP5K,UBE2I,PTEN,STAT5A,NR1H2,NR1I2,DYRK1A,VIRMA,SUMO1,CCND1,CXCL8,CCL3,LMNA,RPA2,PAX9,RPA3,NLE1,PML,RNF113A,HDAC3,HSPA5,BCL6,CNOT2,HMGA1,INSYN1,POU5F1,LHX2,TNIK,RXRG,SIN3A,HNRNPL,PGR,EGLN3,NUP35,VDR,TOP3B,SUPT5H,E2F4,SOX2,H1-3,JUN,SAP30,RBPJ,ZBTB16,LASP1,RBBP7,TRIM37,ASF1A,PAX6,MYC,CREBBP,HNF1B,DCAF4,SP1,COP1,RGMA,ATXN1L,NFKBIB,ELK3,NFKBIA,PRMT5,AP2M1,SNRNP40,FBXO22,ESR2,CDKN1A,CTBP1,KLF3,PPARG,FOS,HDAC5,C1D,EP300,ADRB2,ITGAV,ZBTB5 |
| 1.836e-03 | -6.30 | ZNF512 (zinc finger protein 512) | protein interactions | 84450 | 248 | 91 | 19454 | 5460 |
DLST,RPL37A,RPS9,SNRNP40,RPL35,RPF1,APEX1,RPL19,ESR2,MYC,RAB11A,THAP7,ZNF668,FTSJ3,LMNB1,H1-1,STAU1,NOP53,COIL,BET1,NOTCH2,CCDC71,RPL8,SRSF1,RPS10,HNRNPL,LYAR,ZNF593,HMGA1,IFI16,DDRGK1,NGDN,MRPL18,LHX2,RPL31,SRSF7,RPL28,SRSF4,PAX6,SSRP1,SOX2,RPL18,ZNF330,TNFRSF1B,RBMX2,PRKRA,FGFBP1,RPL13A,RPL7A,RPL26,DNAJC8,RRP7A,RPA3,SIRT7,RAB9A,NPM3,DGCR8,WDR3,NUCKS1,RPL4,UTP23,KLF12,RPA2,ZCCHC17,GRM2,RPL26L1,RPLP0,SRP14,H2AZ1,KRR1,RPL32,CGAS,ZBTB2,SURF6,KLF9,TUBG1,MED27,H2AC4,RPS2,NOL12,RPL10A,RPL3,H3C1,VRK1,RIGI,RPL17,RPSA,AURKAIP1,RPL15,CBX3,RBM34 |
| 1.836e-03 | -6.30 | MECP2 (methyl-CpG binding protein 2) | protein interactions | 4204 | 248 | 91 | 19454 | 5460 |
EZH2,RBPJ,SMARCB1,RPL18,ZNF263,RAF1,MAX,TRMT1L,RPL29,SOX2,H1-6,SRSF8,HMGA1,RIOX2,RPL6,LYAR,SNX1,ZNF593,SIN3A,RPL8,RPLP2,MFAP1,NUFIP2,FXR2,HIRA,NKAPD1,NUP50,SP1,MYC,NOP16,SMARCE1,BTF3,RPF1,CBX5,APEX1,TACO1,CBX3,DDX42,TP53,TAF1D,LBR,FCF1,RPL15,H3C1,MEPCE,RPL17,RPL3,RPL10A,BRD3,TMA16,PPIL4,SUV39H1,TOP1,PRNP,ZBTB2,GTF2B,RPL12,RPL32,PWP2,LMNA,CHMP1A,ZCCHC17,TFB1M,RPL26L1,HEXIM1,SUMO1,CDC42,DGCR8,NUCKS1,HMGB1,BRIX1,UTP23,RPL27,NLE1,TWNK,EXOSC4,CHRAC1,EPHA2,RRP7A,RPF2,RPL7A,PPP1R10,SH3BGRL,CREB1,PSPC1,METAP2,CTTN,EZH1,ZNF330,EIF2AK2,MACROH2A1 |
| 1.840e-03 | -6.30 | cellular modified amino acid metabolic process | biological process | GO:0006575 | 181 | 72 | 18204 | 5365 |
CRTAP,SLC1A1,DIO1,CTSK,GSTP1,ALDH1L1,ABHD16B,SLC1A2,SOD2,GGH,SERINC1,CPT2,EGLN3,CPT1B,GPX1,DPEP1,GSTM3,SHMT1,CHAC2,SLC7A11,DIO3,GLO1,CHDH,GNMT,SULT1B1,FKRP,GCLC,MTHFD2L,GSTM2,GLRX2,PLA2G15,SLC16A10,EGLN2,GSTM5,GGT7,TYMS,AASDHPPT,OSBPL8,GSTA4,PCYOX1L,IDH1,GSTA2,DIO2,CKB,FOLR1,GSTT1,GSTT2B,SLC25A42,HPGDS,CTSB,CRAT,GAMT,GSTK1,SLC6A8,PLSCR1,LPCAT3,SOD1,CRYM,P4HA2,ARL6IP5,PTDSS1,GSTM4,MTHFS,GSTO2,MGST2,G6PD,GSTA1,MMACHC,SLC25A32,ABHD12,NDP,GSTO1 |
| 1.852e-03 | -6.29 | regulation of activated T cell proliferation | biological process | GO:0046006 | 45 | 23 | 18204 | 5365 |
IGF1,IL2RA,HMGB1,EPO,IL18,PPP3CA,MIR181C,IDO1,CD274,FOXP3,IL12B,BTN2A2,IL23A,GPAM,PRNP,IL2,MIR21,MIR30B,AGER,PYCARD,PDCD1LG2,LILRB4,RPS3 |
| 1.853e-03 | -6.29 | CEP76 (centrosomal protein 76) | protein interactions | 79959 | 214 | 80 | 19454 | 5460 |
RPL23,PPP3CA,MRPS26,SMG9,KIAA1143,RPL24,CCDC92,F7,PPFIBP1,CSNK2A1,GMPPB,PRPF19,ERCC3,HSP90AB1,MRPS23,ILVBL,SPTAN1,KCTD10,SNRPD3,RPS16,DCUN1D1,CACNB3,RNF128,RPL9,RPS23,RPS11,TUBB4B,SPG21,HPCAL1,RPS7,RPL17,RFC2,TOB2,PDRG1,RPS4X,CRYBA4,TSSC4,MRPS11,PLCB1,RBM41,RPL23A,TCEA2,EIF1AD,RPL31,UQCC2,CALU,HSP90AA1,MRPS25,MRPS16,GORASP2,SMARCE1,RPS17,RPL26,AKT1,VIRMA,RPL22,CEP97,UBB,TUBB,FBXO22,RBBP4,RPL10L,RPS9,ZMAT2,SCNM1,TUBA1B,DCTD,TCF19,MFAP1,MED23,NDUFAF3,TTLL10,RPS14,MRPS7,HSPA5,COIL,MBD3,RPS15,KDM1A,STK26 |
| 1.853e-03 | -6.29 | GNAI3 (G protein subunit alpha i3) | protein interactions | 2773 | 214 | 80 | 19454 | 5460 |
TFCP2,PIK3CA,NGB,FURIN,NUPR1,DCUN1D5,GNAI3,TOP3B,SOX2,GNG10,KRAS,PSMA1,G3BP1,EPHA4,CNR1,UBE2A,CCR5,BCKDK,GNG5,NTRK2,GPSM3,UBFD1,DPP4,PSMD3,EDEM1,GNG11,YWHAH,HDAC6,CD81,XPO1,API5,ARF6,OSBP,RGS10,STX6,EGLN3,STK3,RAB11B,CAV1,GNB3,DUSP6,RPA2,PAK5,GNG7,METTL14,ATG16L1,TSHR,CD59,DUSP22,EMC1,LPAR1,ADRB2,RGS19,GNB4,RGS2,HSPA5,RPA3,DDX39B,DUSP9,HTR1A,HSPA8,NMRAL1,PMAIP1,DERL1,NRP1,MYC,LDHB,BAG3,AR,LDHA,RHOJ,GNAI2,ESR2,GNB1,OPTN,GAB1,CCNF,GNAO1,RGS5,PCP2 |
| 1.858e-03 | -6.29 | soft_tissue-sarcoma | COSMIC cancer mutations | soft_tissue-sarcoma | 46 | 23 | 16828 | 4835 |
PIK3CA,DICER1,SMARCB1,SRSF2,RB1,CTNNB1,IDH2,PTPN11,AKT1,SS18,RUNX1,EWSR1,SF3B1,HRAS,FGFR1,TP53,MET,KIT,FBXW7,JAK2,CDKN2C,KRAS,IDH1 |
| 1.865e-03 | -6.28 | KLC1 (kinesin light chain 1) | protein interactions | 3831 | 245 | 90 | 19454 | 5460 |
POLR2C,EZH2,KIF2A,SNAPIN,PPP2R1A,PSMD12,PSMA1,KRAS,HNRNPF,VPS26B,RPAP3,RUVBL2,PABPC1,CCT8,AVL9,YWHAB,HSPB1,RASSF8,PSMD10,YWHAG,YWHAH,DPY30,PSMD3,CCT7,DYNC1I2,RPS10,AZIN1,PPP2CB,ARCN1,KLC2,EIF4B,RNF7,PSMB7,PPP1CB,SKP1,PSMC1,ADRB2,MCMBP,EP300,HSPA8,YWHAZ,PSMD1,RUSC2,CUL3,SFN,APEX1,ACTB,PSMD6,SYNE4,TSN,PSMD4,PHF21A,ANAPC2,PSMC3,EXOC3,MAP1LC3B,CAPZA1,RIGI,HNRNPK,PSMA5,MAP4,TSNAX,PSMD7,PTGER4,NFKB1,MYL12A,TRAK2,RAP1B,PTPN1,ACACA,UBE2M,AP1AR,RPA2,PSMC4,HSPA5,PIAS1,KDM1A,PPIH,CLK1,BAP1,RPA3,NAPA,EPHA2,RIC3,ST13,VIRMA,ADRM1,RPS20,PSMC5,CCNF |
| 1.866e-03 | -6.28 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | 19 | 12 | 16828 | 4835 |
GNAQ,MAP2K1,KRAS,HRAS,PIK3CA,PTEN,CTNNB1,RB1,KIT,TP53,AKT1,FBXW7 |
| 1.866e-03 | -6.28 | spindle_and_epithelioid | COSMIC cancer mutations | spindle_and_epithelioid | 19 | 12 | 16828 | 4835 |
TP53,KIT,RB1,CTNNB1,FBXW7,AKT1,PIK3CA,PTEN,HRAS,KRAS,MAP2K1,GNAQ |
| 1.866e-03 | -6.28 | IRF-3 | smart domains | SM01243 | 7 | 6 | 9717 | 2575 |
IRF7,IRF6,IRF9,IRF4,IRF8,IRF3 |
| 1.868e-03 | -6.28 | EEF1D (eukaryotic translation elongation factor 1 delta) | protein interactions | 1936 | 314 | 112 | 19454 | 5460 |
TOMM40,RNF40,CUL2,CUL3,MYC,CRMP1,BRCA1,CCT2,GTF2F1,DLST,APEX1,ESR2,SIAH1,TENT5C,CAVIN2,MATR3,TOMM22,PIH1D1,MAP2K1,CTBP1,EP300,NMRAL1,HSPA8,FOS,ADRB2,STAU1,GPC1,EEF1G,NT5C2,SIAH2,CTNNB1,ATG7,FRA10AC1,CAMSAP2,HSPB1,AGR2,PSMD10,FOSL2,COPS2,EED,FOLR1,JUN,SUPT5H,OARD1,RAF1,MAX,RPL18,PDHA1,CHMP4C,EZH2,RAD21,AHCYL1,UBE2A,USP14,FBXO7,ARHGAP21,CARS1,UBE2H,CDC73,UHMK1,SPOP,CCNF,VIRMA,SMURF1,CYP21A2,CDK7,CFTR,TPT1,ATG16L1,PRKCA,UBE2M,HEXIM1,METTL14,WWP1,GRM2,LMNA,RPA2,CDK1,SQSTM1,RTN4,RNF113A,PML,BAP1,DDX46,SOD1,RPA3,HSPA5,FBXW7,CD81,CSNK2A1,HDAC6,KARS1,DCK,EEF1B2,CDK9,PRNP,RPL15,MLLT6,MAP1LC3B,EEF1A1,RNF8,PPME1,HSD17B10,MAP1B,FAF1,RNF20,MEPCE,HNRNPK,THRAP3,FARSA,TGFBR2,HUWE1 |
| 1.872e-03 | -6.28 | DOCK3 (dedicator of cytokinesis 3) | protein interactions | 1795 | 55 | 26 | 19454 | 5460 |
CAND1,PLEKHF2,ELMO1,SRPK2,HACD3,MAGED2,ARHGAP5,CIRBP,ELMO2,MAT2A,RSPH1,PSMD3,PYCR2,SEC13,ZNF24,XPO1,PSEN1,TBC1D24,ZYX,PSEN2,AKAP1,SURF4,TOP3B,RBFOX2,CCDC47,MRPL47 |
| 1.872e-03 | -6.28 | BCL3 (BCL3 transcription coactivator) | protein interactions | 602 | 55 | 26 | 19454 | 5460 |
PSMB1,GTF2A1,GSK3A,GTF2B,STAT1,CTNNB1,COPS5,HDAC6,CREBBP,NFKB1,AKT1,MAPRE1,SHC1,TRAF6,BCL10,RAB9A,BAG2,EP300,RUVBL2,FOS,RUVBL1,KDM1A,HDAC3,JUN,CTBP1,PIR |
| 1.872e-03 | -6.28 | ZDBF2 (zinc finger DBF-type containing 2) | protein interactions | 57683 | 55 | 26 | 19454 | 5460 |
UBE2H,MYC,PRPF19,PPP1CC,SNRNP40,CDC5L,VIRMA,TMPO,LURAP1,PTPN1,PHF21A,GSK3A,VAPB,CSNK1A1L,CSNK1A1,ACACA,H1-5,SOX2,KDM1A,MSH6,HSPA5,FTL,FKBP8,RPL28,PSMB10,CPNE2 |
| 1.872e-03 | -6.28 | TMSB4X (thymosin beta 4 X-linked) | protein interactions | 7114 | 55 | 26 | 19454 | 5460 |
ACTB,FAM118B,CAV1,PNMA1,ACTA2,TRIM27,HEBP1,ADK,TRIM23,UHMK1,AKAP8L,ILK,RAD21,IGSF21,SMN1,INPPL1,FHL3,SCHIP1,EZH2,CRABP2,ZNF526,PPP4C,ANXA7,KRTAP8-1,TAF1D,CDKN1A |
| 1.872e-03 | -6.28 | PLCB1 (phospholipase C beta 1) | protein interactions | 23236 | 55 | 26 | 19454 | 5460 |
PRNP,ARF6,APEX1,VIRMA,RAB35,HRAS,PLCB2,RHOB,H1-1,NRP1,DPP4,RAB2A,LAMP2,PHB2,KRAS,GNA11,PLCB1,HAPSTR1,NHERF1,KRIT1,CTBP1,TFCP2,GNAQ,PRKCA,PARD6A,SPTBN1 |
| 1.872e-03 | -6.28 | TOR1B (torsin family 1 member B) | protein interactions | 27348 | 55 | 26 | 19454 | 5460 |
RPA3,TMEM87A,TMEM106B,HSPA5,HSCB,TNFSF8,CD1B,GIMAP2,CLEC12B,TMEM59,TMEM106A,DDX39A,H2AX,CBLN4,CFTR,TOR1AIP2,NCR3,SFTPC,GHITM,DNASE1L1,NRSN1,EIF2S2,DNAJB9,GGH,CFC1,SDF2L1 |
| 1.872e-03 | -6.28 | CHD9 (chromodomain helicase DNA binding protein 9) | protein interactions | 80205 | 55 | 26 | 19454 | 5460 |
VIRMA,APEX1,MAD2L1,FBXO22,NKAP,HNRNPL,SYT2,PHF12,BRD3,BRCA1,TIAM1,H2AC4,EDEM1,MYC,COIL,FGF12,CAMKV,NR1I3,VPS26B,TWNK,ADAMTS1,NFKBIL1,CBX3,TULP3,PPARA,SOX2 |
| 1.876e-03 | -6.28 | CCDC88A (coiled-coil domain containing 88A) | protein interactions | 55704 | 211 | 79 | 19454 | 5460 |
HDAC3,KDM1A,TRIM52,STX7,IRF3,RHOU,WWP1,FGFR1,HAUS2,ANXA7,DYRK2,NUP62,ATG16L1,DET1,RND2,CDC42,TENT5C,RHOJ,RAPGEF5,VIRMA,GNAI2,MAD2L1,SMURF1,CTNNA1,RAN,S100A6,PHF21A,MOB4,GSK3A,GANAB,QSER1,RHOB,YWHAZ,LAMTOR1,UBE2H,MAPRE1,COP1,SFN,RAB11A,AKT1,RAB2A,MLF1,DNAJC5,BRINP3,CAPG,RFTN2,RBBP7,KRAS,FLOT1,RIGI,SAR1B,NTRK2,SRSF8,DISC1,METTL21A,GNAI3,RND3,SNX1,RHOH,ARF6,CETN2,CAV1,DIRAS3,CYTH4,NAA11,EGLN3,PEG10,STX6,FUBP3,RAB35,RAC2,GJA1,RHOG,YWHAB,CTNNB1,EXOC1,YWHAH,YWHAG,XPO1 |
| 1.876e-03 | -6.28 | FLVCR1 (FLVCR choline and heme transporter 1) | protein interactions | 28982 | 100 | 42 | 19454 | 5460 |
RHOU,OSTM1,RAB5A,BSCL2,GPC1,KRAS,SLC7A1,STX7,TP53,GINM1,IL2RG,RND2,CDC42,RAB4A,CYB5B,CRELD1,RND3,ARL15,S1PR4,HRAS,RAB35,LMBR1L,RAC2,GJA1,RHOH,RHOJ,ARF6,HNRNPL,CAV1,DIRAS3,LMAN1,SLC7A8,RAB5C,VAMP5,LAMP2,RAB2A,DNAJC5,LAMP3,RHOB,RHOG,LAMTOR1,SLC20A1 |
| 1.876e-03 | -6.28 | FATE1 (fetal and adult testis expressed 1) | protein interactions | 89885 | 100 | 42 | 19454 | 5460 |
CD83,BNIP3L,SYNPR,SLC7A14,SLC7A1,FRMD8,DNAJC30,YIPF4,TRAF2,SEC22A,PLP2,GINM1,SYNGR2,AGTRAP,GOSR2,TIMMDC1,LMNA,SYNDIG1,TMEM74,NRSN1,SYNGR1,UBE2I,SEC23A,FAM177A1,RPRM,INPP5K,SSMEM1,TRAF3IP3,CXCR3,SYNE4,SEC22C,ZCCHC12,FATE1,MARCHF5,SLC38A1,MARCHF3,TMEM179B,BTN2A2,CXCR1,SCAMP5,TMEM11,RIC3 |
| 1.876e-03 | -6.28 | SYNGR1 (synaptogyrin 1) | protein interactions | 9145 | 100 | 42 | 19454 | 5460 |
RGP1,RETREG3,MPDU1,SCAMP2,HAS3,UBE2S,CCNF,MSMO1,MYG1,TMEM45B,SNX1,YES1,TMBIM6,HMOX2,FATE1,SYNJ2BP,CREB3,SLC20A1,ATP1A3,RUSF1,GPAA1,TMEM87A,CERS6,PSEN1,CMTM6,RER1,SLC7A1,TNPO2,DUSP22,SPG21,YIPF3,SYNGR2,RABL3,LEMD3,TMEM14B,GOLGA5,PTRH2,GHITM,SDCBP,LMNA,SURF4,TMEM31 |
| 1.877e-03 | -6.28 | positive regulation of nitric oxide metabolic process | biological process | GO:1904407 | 40 | 21 | 18204 | 5365 |
AKT1,SMAD3,IFNG,IL1B,CLU,MIR99B,TNF,DDAH1,JAK2,TICAM1,SOD2,TMEM106A,TLR4,KLF4,HSP90AB1,HBB,TLR6,CLEC7A,CD36,DDAH2,HSP90AA1 |
| 1.877e-03 | -6.28 | regulation of endocrine process | biological process | GO:0044060 | 40 | 21 | 18204 | 5365 |
CRY1,PTPN11,RAB8B,NKX3-1,UCN,CRHBP,OPRK1,LEP,CRHR1,RETN,SMAD4,NPVF,INHA,GHRL,C1QTNF1,FGFR1,GJA1,OR51E2,TSPO,SPP1,REN |
| 1.878e-03 | -6.28 | cyclin-dependent protein kinase holoenzyme complex | cellular component | GO:0000307 | 56 | 27 | 19108 | 5553 |
BCCIP,PCNA,CKS2,CCND3,CDK9,CCNF,CCNQ,MNAT1,CCNA2,CDK12,CDK5,CCND1,CNPPD1,CDK4,CDKN1A,CCNH,CDKN2D,CDK1,CKS1B,CCNB1,CDK6,RB1,CDK5R1,CDK7,CDK8,CCNI,CCNY |
| 1.880e-03 | -6.28 | positive regulation of post-translational protein modification | biological process | GO:1901875 | 135 | 56 | 18204 | 5365 |
EGR1,RBCK1,KDM1A,NMI,PSMD10,NSMCE3,TICAM1,PTEN,DCUN1D1,CAV1,PHF23,DERL1,CDK5RAP3,DCUN1D3,CRY1,WBP1L,GSK3A,TRAF6,NDFIP1,HDAC3,CUL3,CDKN1B,TOLLIP,HSPA5,UBE2N,UBE2S,UBE2D1,RPS2,TOPORS,ARRDC3,SKP1,PIAS1,UBE3A,MUL1,MAGEC2,DCUN1D5,FZR1,CDC20,BIRC2,UBB,RCHY1,UBE2L3,BCL10,NOP53,RWDD3,ANGPT1,UBE2V1,PTPN22,UBE2V2,STUB1,FAM107A,PELI1,TANK,FBXW7,GABARAP,HUWE1 |
| 1.886e-03 | -6.27 | granulocyte chemotaxis | biological process | GO:0071621 | 82 | 37 | 18204 | 5365 |
CCL8,S100A8,CCL11,JAML,CXCL13,ADGRE2,CXCL3,PIK3CG,CXCL1,PDE4B,CKLF,CCL3,SYK,IL1B,CCL1,CXCR1,CCL23,PPIB,CCL25,SCG2,CCL18,CCL24,CXCL11,PPIA,CCL4L1,CCL2,SRP54,CXCL8,CCL5,CXCL9,CXCL10,LGALS3,DPEP1,FCER1G,XCL1,TGFB2,CX3CL1 |
| 1.890e-03 | -6.27 | TRIM33 (tripartite motif containing 33) | protein interactions | 51592 | 445 | 153 | 19454 | 5460 |
TMX3,DHX9,MDC1,RPL17,MSH6,CSE1L,THRAP3,H3C1,SEM1,EGR2,TP53,RRM1,C1QC,CHAMP1,CBX3,TFRC,NELL2,UBE2N,COQ8A,SMAD3,CAV1,DBT,TOMM70,CDK9,THOC1,PRNP,CAND1,FZR1,SPPL3,TPM3,HDAC6,SSBP4,MAP4,KPNA1,ESYT1,SMAD4,TUBG1,AOX1,H2BC12,HSPB2,FAM53C,PML,RPA3,SOD1,DVL2,MARS1,HSPA5,SMC4,GTF2I,EIF5B,CCNA2,SF3A1,RARS1,METTL14,RPA2,JUP,UBE2I,TRIM24,GANAB,CTNNA1,CCNF,VIRMA,CDC20,GPX1,GMPS,AR,ST13,KPNA6,RUNX1,NTAQ1,PTPN11,RSPH1,CDC16,GGCX,CALU,SMAD2,ANAPC4,ATP1A1,PIP4K2C,DNAJC10,BAG2,FHL3,RABGGTB,RPAP3,EWSR1,PABPC1,SSRP1,MCM6,KCTD17,TRIM37,ASF1A,JUN,TRAF2,SOX2,ACTN4,SSBP3,POLR2C,PNMA2,EZH2,PLS3,RPN1,NUP35,SUMO2,OSBP,SNX2,GFOD1,CTNNB1,XPO1,LAMP2,YWHAB,DDX1,CDC23,NUP50,HADHA,SF3B1,HSPA8,SAT1,FOS,XRCC5,RFC4,TRIM52,UBE2D3,EDEM3,SSBP2,NUP62,ELF5,EIF4B,KLC2,PSMB7,CRYAB,PRMT5,ZMYM2,PELO,VDAC2,PNMA1,FAU,ESR2,MAD2L1,TUBB,MATR3,MCM4,MCM3,PSMD1,RNF40,LDB1,CUL3,ACO2,LMO2,CREBBP,MYC,LMNB1,RBM27,BRCA1 |
| 1.892e-03 | -6.27 | regulation of synapse organization | biological process | GO:0050807 | 246 | 94 | 18204 | 5365 |
NLGN1,UBE3A,EPHA4,TIAM1,LRRTM1,ZDHHC15,PAFAH1B1,LRRTM3,CDC42,CTTNBP2,CDC20,SLITRK5,ROCK1,C1QL3,HSPA8,DAG1,PLXNC1,NEGR1,SNAP25,CFL1,GPC4,CDK5R1,ARF4,C1QL2,SYNDIG1,NEUROD2,PRNP,C1QL1,HOMER1,SLITRK1,MECP2,SIPA1L1,GPM6A,TPBG,EFNA5,CHRNB2,LRFN3,MEF2C,CHMP2B,CAMKV,AMIGO1,YWHAZ,GPRASP3,RAP2A,CAMK1,PSEN1,MIR30B,CLSTN3,NTRK2,ANAPC2,FLRT2,CBLN2,PPFIA2,IL10,TNF,SLC7A11,CDH8,OXTR,CNTNAP1,LRRTM2,SLITRK2,CTNNB1,NTNG2,CDK5,AKT1,DKK1,SETD5,WNT7A,ABHD17A,WASL,RHOB,IL1RAP,LRRC24,FCGR2B,TUBB,PTEN,DISC1,ADNP,TUBA1A,LRRC4B,GRID1,ASIC2,CTNNA2,FLRT3,TLR2,NLGN2,GHRL,NEFL,DMPK,LHFPL4,CBLN1,LRRN1,LRTM2,ARF6 |
| 1.893e-03 | -6.27 | CHCHD6 (coiled-coil-helix-coiled-coil-helix domain containing 6) | protein interactions | 84303 | 80 | 35 | 19454 | 5460 |
FBXO7,MYC,TMED4,SLC25A46,HTRA2,SLC2A1,TRAK2,SLC1A1,ARL4D,AIFM1,HACD3,COX4I1,CHCHD3,ERLIN1,APLNR,PARL,PLGRKT,SLC25A12,HNRNPL,APOO,FAXC,MGARP,TIMM29,B3GNT2,MTX2,ZER1,SAMM50,SLC2A8,LRRN4CL,PML,SFXN1,CHCHD2,SLC25A51,DNAJC30,PHB2 |
| 1.893e-03 | -6.27 | PIR (pirin) | protein interactions | 8544 | 80 | 35 | 19454 | 5460 |
PMM2,PSMB2,ACO2,CAPG,CFL1,TIA1,CFL2,AGR2,ADK,NME2,HTRA2,MT1X,SMAD9,NFKBIA,SRXN1,SIN3A,FAHD1,GNPDA1,DSTN,SNX3,MIF,UBE2L3,PPIA,MAP1LC3B,DDX39A,GNPDA2,ANXA7,FKBP1A,SOD2,PEBP1,SOD1,HSPA8,SRI,HSPE1,CRYZ |
| 1.893e-03 | -6.27 | Rbm14 (RNA binding motif protein 14) | protein interactions | 56275 | 80 | 35 | 19454 | 5460 |
CCNF,EIF4A3,CTTN,ZMAT5,LSM5,RPL7L1,PEG10,RBM42,RPL19,SNRPB,DIS3L,UTP6,NOA1,FHIT,EXOSC1,RPS26,DDX1,MAGOH,RBM7,SNRPA,RBM3,YTHDF1,RBM22,FARSA,TXNL4A,UBL5,PPIL3,SUPT5H,MREG,SNRPN,ESS2,EXOSC8,CTBP1,LMNA,TFIP11 |
| 1.893e-03 | -6.27 | APEH (acylaminoacyl-peptide hydrolase) | protein interactions | 327 | 80 | 35 | 19454 | 5460 |
TOP3B,TP53,SHMT1,APEH,RPA2,EZH2,USP39,HSPA8,ZYX,PPM1G,MAP1B,PREPL,SAR1B,CNOT7,TOLLIP,RUNX1,LAMP2,CARS1,KARS1,MOV10,VPS26A,PDCD4,DNAJC7,BRCA1,LGALS8,H1-10,CTTN,SRSF1,POLE3,NMI,APEX1,CAND1,STAT1,TAX1BP1,PRNP |
| 1.894e-03 | -6.27 | EYA3 (EYA transcriptional coactivator and phosphatase 3) | protein interactions | 2140 | 66 | 30 | 19454 | 5460 |
SNRNP40,TIMM21,TCEAL1,ESR2,EGLN3,CACYBP,TOMM70,NPPC,EEF1AKMT3,PSMB1,PSMD14,THTPA,DIS3L,TSEN34,PSMD1,EYA3,HUWE1,ZDHHC17,GRPEL1,PML,BAG2,EWSR1,SIX5,STX17,PTRH2,NME1,PSMC3,MTMR2,TMEM126A,H2AX |
| 1.894e-03 | -6.27 | AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5) | protein interactions | 55326 | 66 | 30 | 19454 | 5460 |
CAMK2G,HSCB,TNFSF8,NPTN,VDAC1,HS2ST1,FTL,RPA3,OSTM1,TMX2,NMRAL1,PRND,RPA2,CTLA4,AQP3,GHITM,GPR35,HCST,DYNC1I2,APLNR,RAMP3,TNFRSF9,STARD3NL,SPOP,PPTC7,CDH13,LAMP2,GPBAR1,SCN3B,HM13 |
| 1.894e-03 | -6.27 | NEK8 (NIMA related kinase 8) | protein interactions | 284086 | 66 | 30 | 19454 | 5460 |
CACYBP,IDE,HSP90AB1,SPPL3,MOB4,STUB1,AIP,DNAJC7,HSP90AA1,CA2,HSPB1,S100A11,FKBP4,CAPG,SLC25A1,SFN,PTGES3,UNC45A,TTC4,RPAP3,TTC1,NEK9,SLC25A10,PIH1D1,ACVR1,SSR1,TUBA1A,NUDCD3,NEK7,TOP3B |
| 1.894e-03 | -6.27 | SLC2A4 (solute carrier family 2 member 4) | protein interactions | 6517 | 66 | 30 | 19454 | 5460 |
PSMD7,SDF2L1,SERPINH1,HSP90AA1,FIS1,MAP1S,CREB3,CTSD,GAPDH,CFL1,SLC25A4,UBE2N,SMAP2,ACOX1,UBE2I,CHCHD6,IDH2,P3H1,FKBP10,UBA52,SRFBP1,HADH,ACTN4,AP1M1,RAB29,TMEM263,AKT2,PDIA6,IDH1,ARFIP1 |
| 1.901e-03 | -6.27 | regulation of monoatomic cation transmembrane transport | biological process | GO:1904062 | 309 | 115 | 18204 | 5365 |
CD63,MIR192,XCL1,SCN3B,CHP1,ISCU,MIR24-1,CX3CL1,CACNB3,LACRT,KCNMB1,CXCL11,VMP1,BAK1,TMBIM6,GSTM2,MIR30D,PPP3CA,RANGRF,DRD3,HECW1,CAB39,MIR208B,TESC,PCSK9,SLMAP,PML,ACTN4,SPHK2,JPH4,TMSB4X,KCNS1,FKBP1A,VAMP2,NPSR1,CXCL10,PPP3R2,MIR200C,ATP2B4,CRHR1,SRI,FGF13,SUMO1,PLP1,MIR448,KCNIP2,DRD1,CACNB4,PRKCE,G6PD,SCN2B,PLN,DLG1,PPIF,SLC8A1,ATP1A2,F2,ATP1B1,IFNG,WWP2,DPP10,CXCL9,CACNB2,KCNC1,IL13,MMP9,MIR1-1,SESTD1,HPCA,BAX,SCN1B,ATP1B3,VDAC1,TRPC1,STAC3,TMEM38B,YWHAH,KCNJ2,APLNR,FGF12,THY1,PIK3CG,PDE4B,PRNP,PHB2,SNTA1,HOMER1,NETO1,OXSR1,PSEN2,EDNRA,CAV1,KCNAB1,CLIC2,EPO,COX17,CAV3,UBASH3B,GPR35,FXYD6,NDUFA4,FKBP1B,MIR210,GSTO1,AMIGO1,MIR208A,KCNIP3,NOS1AP,TLR9,MIR153-1,MIR21,MIR212,STIM1,SELENON,OPRK1 |
| 1.903e-03 | -6.26 | Signaling by FGFR1 | REACTOME pathways | R-HSA-5654736 | 50 | 26 | 10285 | 3229 |
FGF17,FGF10,FLRT3,SPRED2,SRC,SHC1,FGF3,FRS3,UBB,SPRED1,CBL,PPP2R1A,FGF22,UBA52,RPS27A,KRAS,PTPN11,FGF1,PIK3R1,FLRT2,PIK3CA,FGF23,FGFR1,PPP2CB,HRAS,GAB1 |
| 1.903e-03 | -6.26 | regulation of synapse structure or activity | biological process | GO:0050803 | 252 | 96 | 18204 | 5365 |
MIR30B,CAMK1,PSEN1,FLRT2,CBLN2,ANAPC2,CLSTN3,NTRK2,GPRASP3,YWHAZ,CAMKV,AMIGO1,RAP2A,MEF2C,LRFN3,CHRNB2,EFNA5,CHMP2B,SIPA1L1,GPM6A,MECP2,SLITRK1,TPBG,C1QL2,CDK5R1,ARF4,GPC4,CFL1,SNAP25,PRNP,C1QL1,HOMER1,NEUROD2,SYNDIG1,DAG1,C1QL3,HSPA8,NEGR1,PLXNC1,CDC20,CTTNBP2,CDC42,LRRTM3,ROCK1,SLITRK5,EPHA4,NLGN1,UBE3A,PAFAH1B1,ZDHHC15,LRRTM1,TIAM1,LHFPL4,ARF6,LRTM2,CBLN1,LRRN1,NLGN2,TLR2,FLRT3,CTNNA2,DMPK,NEFL,GHRL,GRID1,LRRC4B,TUBA1A,ADNP,ASIC2,SYBU,TUBB,DISC1,PTEN,LRRC24,IL1RAP,RHOB,FCGR2B,DKK1,AKT1,NTNG2,CDK5,WNT7A,ABHD17A,WASL,SETD5,LRRTM2,CNTNAP1,OXTR,CTNNB1,SLITRK2,PPFIA2,PPT1,IL10,CDH8,SLC7A11,TNF |
| 1.903e-03 | -6.26 | Hedgehog 'off' state | REACTOME pathways | R-HSA-5610787 | 101 | 46 | 10285 | 3229 |
UBB,PRKACB,UBA52,PSMD14,PSMD7,PSME1,SKP1,PSMD10,PSMB3,IFT57,ADCY2,PSMB6,PSMA2,PSMB10,PSMA5,PSMB11,PSMC5,PSMA4,TULP3,PSMC4,ADCY3,PSMB5,PSMA3,PSMB1,PSMB7,PSMD3,PSMD4,RPS27A,PSMA1,PSMC3,SEM1,PSMB9,PSMB4,PSMD6,PSME2,CSNK1A1,PSMA6,WDR19,PSMD1,PSMB2,IFT52,SUFU,PSMC1,PSMD12,RPGRIP1L,IFT172 |
| 1.905e-03 | -6.26 | monoatomic cation homeostasis | biological process | GO:0055080 | 505 | 179 | 18204 | 5365 |
FGF23,CYP27B1,MAIP1,ALPL,MT1A,HEXB,CHRNA7,SLC41A1,TMEM199,B2M,SLC30A5,CCL1,ZNHIT1,CCDC47,CCDC22,FATE1,SV2B,STIM1,ARF1,SLC39A13,CLIC4,SNX10,CACNB2,SOD2,SLC39A7,RHCG,NEO1,ADORA1,FGFR1,P2RY1,EXT1,COMT,ATF4,TM9SF4,TMEM165,FASLG,SLC4A10,CYB561,CCL11,PSEN2,COX11,SLC25A23,CCL8,HSP90B1,PML,TASL,NPPC,GLRX5,DISC1,SLC11A2,ANKH,GPR89A,SRI,MT1M,BOLA1,CACNB4,BOLA3,SLC12A2,DMPK,CFTR,TMEM203,PLN,MT2A,VPS54,F2,CCR2,BOLA2B,CCL19,SLC25A27,SLC39A10,KCNJ10,ISCU,ATP6V0E1,PPT1,CYP11B2,STC1,VAPB,TMEM106B,SELENOK,TFRC,CYBRD1,ATP1A1,HFE,CXCL12,KCNMA1,CD40,CCL23,TMBIM6,COX19,CYP4F12,SLC22A17,SMDT1,S100A8,EDNRA,CAV1,FTL,ATP6V1A,KCTD17,CIB2,CAV3,IREB2,FKBP1B,SNAPIN,TPT1,NPTN,KLHL3,MLLT6,ATP2C1,PSEN1,CIB3,FXN,ATP1A3,SLC39A9,AQP11,SELENON,RMDN3,UBE3A,STOML2,CCL5,ATP6V0B,FTH1,BAX,MYC,ATP1B3,LAMP2,CNNM4,CA2,HTR2A,TRPC1,ATP6AP2,KCNJ2,VPS33A,CCL3,RNASEK,SLC1A3,PRNP,MT1X,GRM1,ATP6V1D,CAV2,ATP2B4,SLC4A8,LACC1,CCR1,PRKCB,FRRS1,NDFIP1,SLC30A7,RGN,GRIA1,PICALM,TRIM24,ATP1A2,SLC8A1,SOD1,CNR1,ATP1B1,FIS1,IL1A,CHP1,CALR,BOK,TF,MT3,SLC1A1,HYAL2,RHAG,VDR,BAK1,ATP5F1B,ATP6V1G1,P2RY4,SLC31A1,SMAD4,DRD3,MT1E,FTHL17,ACO1,PRND |
| 1.905e-03 | -6.26 | DNAJC14 (DnaJ heat shock protein family (Hsp40) member C14) | protein interactions | 85406 | 47 | 23 | 19454 | 5460 |
DDX42,CCDC47,TOP3B,SEC62,OTULINL,DRD1,ADRB2,EMC1,FKBP8,TNFSF12,GRPEL1,TEX264,EMC2,DERL1,MTDH,BSCL2,PSMD14,OSBPL8,DDRGK1,SEC63,BTG3,UBE2N,SEC61B |
| 1.905e-03 | -6.26 | RMND5B (required for meiotic nuclear division 5 homolog B) | protein interactions | 64777 | 47 | 23 | 19454 | 5460 |
UBE2D3,RANBP10,MAEA,GID8,EWSR1,MKLN1,ADAMTS1,UCK2,UBE2W,SOX2,EMILIN3,PSMD6,BMP1,CDK9,SMAD4,MRPL18,UBE2E3,YPEL5,ARMC8,UBE2H,UBXN6,SETD5,SPON1 |
| 1.905e-03 | -6.26 | TMEM115 (transmembrane protein 115) | protein interactions | 11070 | 47 | 23 | 19454 | 5460 |
GJA1,CYB5R3,LMBR1L,TLCD4,STX6,SYNE4,SCN3B,RAB11A,CREB3,RABAC1,BSCL2,TMT1A,TMX2,RPL27,SAR1B,SACM1L,ZDHHC17,MRPS33,KRAS,OTULINL,YIPF5,MANBAL,RAB4A |
| 1.905e-03 | -6.26 | SPHK1 (sphingosine kinase 1) | protein interactions | 8877 | 47 | 23 | 19454 | 5460 |
MAP1S,DHPS,GMPS,BECN1,TRAF6,SMG8,CTU1,IL10,CTSB,SRC,AANAT,TOP3B,TOMM22,QTRT2,TRAF2,WRAP53,LEMD3,PPM1G,TTC1,EP300,PIK3CG,RIGI,RDH11 |
| 1.905e-03 | -6.26 | MSLN (mesothelin) | protein interactions | 10232 | 47 | 23 | 19454 | 5460 |
CBLN4,MPV17,NCR3,SFTPC,FKBP14,RING1,APPBP2,PCGF2,EMC2,NDUFB5,PPY,EMC1,MRPL16,BTF3,HDAC6,GGH,SDF2L1,DNASE1L1,ATP6V1A,GXYLT1,APEX1,RALA,LAMTOR3 |
| 1.910e-03 | -6.26 | regulation of muscle cell apoptotic process | biological process | GO:0010660 | 93 | 41 | 18204 | 5365 |
MIR21,MIR140,HAND2,ATF4,PPP1R10,SMAD4,RGL2,PPARG,HEY2,CAPN2,BAG3,IL12A,MIR30E,HSPA8,MIR320A,MIR20A,STUB1,MIR17,SOD2,MIR34A,NUPR1,MIR210,PDCD4,MIR195,MIR16-1,MIR145,MIR1-1,IGF1R,BMPR1A,MIR24-1,TP53,IL12B,LRP6,IFNG,MIR28,IGF1,MIR106B,PDE1A,NFE2L2,JAK2,DIPK2A |
| 1.910e-03 | -6.26 | PTPRZ1 (protein tyrosine phosphatase receptor type Z1) | protein interactions | 5803 | 34 | 18 | 19454 | 5460 |
CDK5R1,DDX39A,MGAT5B,CTNNB1,CSK,TNR,ITGAV,ADD2,CNTN1,PTN,PTPRZ1,LGALS3,HMGB1,PRNP,VEGFA,ACTA2,SPECC1L,IL34 |
| 1.910e-03 | -6.26 | EID3 (EP300 interacting inhibitor of differentiation 3) | protein interactions | 493861 | 34 | 18 | 19454 | 5460 |
EID2,CREBBP,MAGEB1,MAGEH1,VCPIP1,NAB2,SMDT1,MAGED2,HAPSTR1,APPBP2,MAGED4B,ACSL4,MAGEC2,FBXO25,TSC22D3,NSMCE3,NDN,AKAP12 |
| 1.910e-03 | -6.26 | PPBP (pro-platelet basic protein) | protein interactions | 5473 | 34 | 18 | 19454 | 5460 |
CCL21,SCFD1,CXCR1,PLEKHJ1,CCL5,CCL28,COPS7A,CXCL12,CCL8,CXCL10,CXCL11,CXCL9,MOB3B,CMTM6,COX17,PMAIP1,ALB,CXCL14 |
| 1.910e-03 | -6.26 | LHPP (phospholysine phosphohistidine inorganic pyrophosphate phosphatase) | protein interactions | 64077 | 34 | 18 | 19454 | 5460 |
HNRNPL,SERTAD1,RPIA,TUBB,EEF1G,GDPGP1,MYG1,HSP90AB1,TRIM27,HSPA8,HMX2,HSP90AA1,CALU,CLIC2,TOP3B,ACTN4,MYH1,EEF2 |
| 1.917e-03 | -6.26 | ER to Golgi Anterograde Transport | REACTOME pathways | R-HSA-199977 | 133 | 58 | 10285 | 3229 |
NAPG,DCTN3,MIR711,SAR1B,SPTAN1,ARCN1,SCFD1,DCTN4,CTSC,TRAPPC3,ARF1,RAB1B,RAB1A,TMEM115,NAPA,GRIA1,KDELR2,STX17,DYNC1I2,TMED7,SEC13,TRAPPC2L,BET1,SERPINA1,COPE,COG1,TRAPPC4,STX5,SPTBN1,MIA2,CNIH1,GOSR1,YKT6,TMED3,CD59,COPZ2,TMED9,TRAPPC10,ARFGAP3,TRAPPC1,SEC22C,ARFGAP1,DYNC1I1,FOLR1,ARF4,TRAPPC6A,DYNLL1,LMAN1,TRAPPC6B,SEC23A,DCTN6,BET1L,SEC22A,KDELR1,GOSR2,PREB,SEC22B,TFG |
| 1.919e-03 | -6.26 | regulation of mitochondrial membrane permeability | biological process | GO:0046902 | 58 | 28 | 18204 | 5365 |
GCLC,MIR17,TMEM14A,ATP5IF1,SLC25A31,SLC35F6,PPIF,BCL2L1,NAIF1,BLOC1S2,MIR29C,VDAC2,MUL1,TP53,BOK,SLC25A4,BAX,PMAIP1,GSK3A,IER3,BAK1,BAD,MIR29A,BNIP3L,PPM1K,ACAA2,SLC25A5,CNP |
| 1.920e-03 | -6.26 | ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5) | protein interactions | 25921 | 103 | 43 | 19454 | 5460 |
RHOG,STYK1,UBE2N,RAB35,HRAS,ARL11,RAC2,RNF128,GJA1,RHOH,ARF6,CAV1,STX6,DIRAS3,TP53,TOP3B,RAF1,GOLGA7B,NUPR1,RND3,NTRK2,KRAS,EPHA4,GOLGA7,FLOT1,RAB11A,RAB2A,DNAJC5,MYO6,RHOB,BRCA1,LAMTOR1,RHOJ,SRPK2,CDC42,RND2,PPP1CB,ARL15,RHOU,RAB9A,RAB5A,STX7,CLDND1 |
| 1.920e-03 | -6.26 | GNA11 (G protein subunit alpha 11) | protein interactions | 2767 | 103 | 43 | 19454 | 5460 |
CD81,GNG2,HDAC6,P2RY1,TTL,PLCB1,ABCE1,GNG5,SLC16A1,KRAS,HTR2A,GNG10,GNG3,NHERF1,TFCP2,NUPR1,FAIM,CCNF,EDNRA,RHOJ,GNB1,ESR2,RAB11A,PAPOLA,USP14,RHOB,FYTTD1,TSPAN15,RHOU,DUSP9,RPA3,HADHA,TMEM185A,HSPA8,ADRB2,GNB4,DUSP22,CFTR,CDC42,TSHR,CD46,RPA2,NOL7 |
| 1.920e-03 | -6.26 | CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2) | protein interactions | 55454 | 103 | 43 | 19454 | 5460 |
SYNE4,B3GALNT1,CREB1,CYB5R3,RMDN3,RETREG3,UBE2I,MFSD14B,CSGALNACT1,ATF1,SLC30A5,TPST1,GOSR1,CLEC12B,LPAR1,NDUFC2,LMNA,TMX4,UTP15,SLC35E3,GINM1,FUT8,GOSR2,CX3CL1,TNFSF18,EXTL2,SSMEM1,HSD17B11,FUT1,STX5,LMBRD1,MCOLN1,BPNT2,LRRC57,ST3GAL4,EMC4,FCGR2A,SLC35A5,EMC8,FKRP,GPAA1,EMC2,TMEM59 |
| 1.925e-03 | -6.25 | regulation of organelle organization | biological process | GO:0033043 | 1201 | 399 | 18204 | 5365 |
HNRNPA1,CDC16,FCHSD2,ZNF207,G3BP1,ADD2,SPEF1,NUPR1,CDC20,FZR1,CDC42,SFRP1,FLCN,TMSB10,IER3,ARFIP1,ANAPC4,FERMT2,MYC,MARCHF5,SSBP1,CDK1,INPP5K,PSRC1,TRIM36,PDCD5,WDR45,MTCH2,CDK5R1,GDI2,CSF2,TNKS,ARPC2,MAVS,SSH3,SMG5,MCOLN1,CAV3,RUVBL2,EFNA5,KCTD17,ANAPC15,CNTROB,SEPTIN7,CD28,MAD2L1BP,SWAP70,TRIM54,BRCA1,TACR1,HTRA2,MTM1,TNKS2,FXN,MIR149,OSBP,IL1A,SMC4,PLSCR3,NCK1,SEC22B,SPC24,ADD1,DYRK1A,RAB1B,TRIM37,GCLC,WASF3,ADRB2,PROX1,C9orf72,TOM1L2,CCR7,PIWIL2,TPPP,SEMA5A,VPS4B,MACROH2A1,TMOD2,CAV2,ANAPC11,MAD2L1,TTC8,NCKAP1,CCT2,PFDN2,IL5,SKA3,HNRNPC,MAP2K1,DRG1,BAZ1B,ABITRAM,CTNNA2,STAT2,FEN1,CCL21,MIR20A,SUB1,RAB3A,DLG1,SLC35F6,CNOT6,CBLN1,FIS1,EFNB1,BECN1,FKBP8,MAP1S,CDK2AP2,TP53,ARF1,LCMT1,CLIC4,SKA2,TNFSF10,LPAR1,SDC4,ACTL6B,SDCBP,NEK7,MIR1-1,SKA1,CYRIA,CHMP1B,RAD1,TMEM33,TRIM27,GHITM,TFPT,ARF4,HUWE1,TMEM14A,CCL11,CEP97,CEP70,MKKS,MIR335,RAD21,AP1AR,ADCK1,ATAT1,CAPG,CCSAP,CHMP5,RHOG,MAPRE1,PRKCQ,DCP2,F11R,CDKN1B,KLHL22,TSPO,TMOD1,PTGER4,DSTN,CHMP4C,SCFD1,PPARG,STN1,MUL1,ROCK2,CX3CL1,CAPZA1,HAUS2,TBC1D1,TNF,ACTB,SPATA4,RPS3,TMEM106B,RAB11A,SLAIN2,MID1IP1,LRRTM2,RUVBL1,MSX1,SLC25A4,CXCL12,INO80C,STUB1,MAPRE2,BCL7B,TAPT1,IL1RAP,ZNF304,HRAS,PYCARD,CCT8,RNF5,S100A10,PREB,TBC1D24,ATG3,TBC1D19,TMEM39A,TMSB4X,SH3GLB1,TBC1D13,PSMD10,WDR44,SLC25A5,IK,RB1,CTTN,TBC1D10C,LRRC4B,TBC1D5,MIR214,TBC1D17,LMAN1,BCL7C,TBC1D16,ARF6,PIP4K2C,TBC1D25,G3BP2,GPM6B,LRRTM1,CHMP1A,MIEF1,CFL2,MMP9,ACAA2,TOM1L1,BAX,USP6NL,VDAC1,AURKAIP1,CPLX3,MORC2,ACTL6A,DAPK3,MAP4,SLX1A,SMARCE1,CLIP3,HAX1,SAR1B,CHMP2A,GPR65,MAD2L2,ARPC3,NCAPG2,RMI2,MNS1,CDC42EP4,CHMP2B,PMAIP1,UBE2B,RGCC,SMARCD3,PLCB1,PPP1R10,MIR21,ANAPC2,SYT4,MSX2,SIRT7,CALR,BOK,SNX18,PDCD10,CNOT2,DKC1,EP300,IGF1,RALA,GPX1,CYFIP2,CCL24,BAK1,NPR2,MAP1B,CTNNB1,IL1B,TGFB3,AKT1,TBC1D4,FAM107A,LMNA,SMAD4,INO80E,DRD3,SLC25A31,CCT7,PRMT5,PLA2G5,NRP1,PKIB,BST2,TSG101,STXBP1,MCPH1,BCL2L1,PARL,LCP1,BAD,GSK3A,PRKCE,CPLX2,DVL2,PID1,MLLT11,MET,BUB3,ODAM,RIOK2,CDC42EP2,MSN,RND2,PAK2,ATP5IF1,PSMG2,SPTAN1,BMERB1,CDC23,STX5,PIK3CA,CD47,CAMSAP2,BIRC5,PAFAH1B1,TOM1,USP30,SURF4,ROCK1,SMARCA5,SRC,FAM162A,MGARP,SQSTM1,RNF41,STX18,HNRNPA2B1,EPS8,COTL1,NDC80,SMARCB1,MECP2,PRELID1,MTPN,FBXO7,PRMT6,NSMCE3,BNIP3L,NF2,CAPZA2,RND3,CPLX1,PIK3R2,CUL3,PIK3R1,BICD2,NBN,CCNB1,CAPN2,CCT5,STMN2,TCP1,WEE2,SMAD3,SPTBN1,CNOT6L,RAB33B,TFRC,DUSP1,TMOD3,ESAM,HNRNPD,TRIM32,ARFGEF1,RALB,NUF2,CLU,TMED9,HDAC6,S100A8,FBXW7,PDE2A,PML,NUP62,MAPKAPK5,EHD3,PHF23,HCLS1,FGF13,TESK1,FKBP4,RAB5A,CCNF,NEK2,CD2AP,CDC42EP3,PPIF,FEZ1,XRCC5,CYRIB,PICK1 |
| 1.927e-03 | -6.25 | DPCD (deleted in primary ciliary dyskinesia homolog (mouse)) | protein interactions | 25911 | 29 | 16 | 19454 | 5460 |
RPAP3,RUVBL2,HMCES,SMAP2,EXD2,DNAAF10,RUVBL1,BAG3,TUFM,COPS5,TBK1,TNFSF13,BRD3,LSM3,NUFIP2,SMAD4 |
| 1.932e-03 | -6.25 | HIV Life Cycle | REACTOME pathways | R-HSA-162587 | 152 | 65 | 10285 | 3229 |
CHMP2B,NCBP2,SUPT5H,CHMP4C,VPS4B,NUP62,NUP153,GTF2E1,CHMP2A,GTF2H5,NUP35,RPS27A,TAF9,SSRP1,ERCC3,TAF11,GTF2B,CCR5,FURIN,XRCC5,CD4,RAN,VPS28,CDK9,NUP37,NUP107,XPO1,POLR2I,NUP42,GTF2F1,GTF2H4,VPS4A,TSG101,POLR2C,VTA1,HMGA1,FEN1,POLR2B,PPIA,TAF2,MNAT1,CDK7,KPNA1,GTF2E2,RANBP1,UBB,TCEA1,POLR2L,UBA52,POLR2D,GTF2H2,GTF2F2,GTF2A2,SUPT4H1,ELOC,POLR2G,TAF10,TAF7,POLR2F,CXCR4,NUP50,CHMP5,CCNH,BANF1,GTF2A1 |
| 1.938e-03 | -6.25 | HISTONE_H2A | prosite domains | PS00046 | 15 | 10 | 12186 | 3388 |
H2AX,H2AC14,H2AC7,H2AC6,H2AC4,H2AC25,H2AJ,H2AC1,H2AZ2,H2AZ1 |
| 1.938e-03 | -6.25 | SYNTAXIN | prosite domains | PS00914 | 15 | 10 | 12186 | 3388 |
STX18,STX17,STX7,STX12,STX10,STX11,STX16,STX6,STX5,STX1A |
| 1.939e-03 | -6.25 | Mito_carr | pfam domains | PF00153 | 53 | 26 | 17795 | 5224 |
SLC25A24,SLC25A21,MTCH2,SLC25A20,SLC25A46,SLC25A11,SLC25A1,SLC25A44,SLC25A39,SLC25A4,SLC25A45,SLC25A31,SLC25A10,SLC25A12,SLC25A14,SLC25A23,SLC25A3,SLC25A28,SLC25A17,SLC25A26,SLC25A32,SLC25A27,UCP2,SLC25A5,SLC25A42,SLC25A51 |
| 1.940e-03 | -6.25 | KLF15 (KLF transcription factor 15) | protein interactions | 28999 | 264 | 96 | 19454 | 5460 |
MRPS21,ZNF330,PPP2R5E,TRIM24,QSER1,MRPS28,MRPS16,EIF3G,IGF2BP1,RPS17,MRPL41,RPS15,MRPL17,GTF2I,MRPL20,ZNF319,SQSTM1,MRPS34,E2F6,RPL26L1,HNRNPH3,MRPL10,BRMS1L,MRPS23,MRPL24,HACD3,MRPS9,PSMB1,RB1,GATAD1,MYBL2,AKAP8L,SUV39H1,PSMA5,MRPL22,RPS13,RING1,MRPS18B,RBM34,PSMC3,ILF2,YTHDF2,MRPL47,ZMYM4,LBR,ING1,PRRC2A,PSMB6,SCNM1,VPS72,PHF12,MRPL13,RPL37A,FTSJ3,MRPS25,RPS5,PSMA4,NOP16,PIK3R3,CREBBP,PSMD1,RPL39,MRPL16,STAU1,NOP53,MRPS7,EP300,MRPS18A,PSMB7,PSMB3,TIMM10,MRPL12,CCAR2,RPS10,TCF21,PSMB4,MRTO4,PHB1,HP1BP3,ZHX1,MRPS26,MRPS35,MMUT,YWHAH,ZBTB14,ZNF609,PSMA1,G3BP1,HNRNPF,PSMA2,FOXP4,RPL28,PPAN,LSM14A,BCL9,RPS11 |
| 1.943e-03 | -6.24 | endomembrane system organization | biological process | GO:0010256 | 558 | 196 | 18204 | 5365 |
GORASP2,CSNK1A1,TMED3,YIPF4,SGTA,BET1,STX17,RETREG1,AP3S2,CHMP4C,CHMP5,YWHAZ,TMED5,CCDC47,TLCD2,VRK1,MYRF,EMC8,EMC9,TMEM170A,STX18,NECTIN2,SQSTM1,FASLG,PARP11,ZBED3,SPTSSB,HIKESHI,TMED7,TOR1B,HUWE1,TMEM147,CHMP1B,LARGE1,TRAM1,ANO3,TMEM33,RAB30,SRGN,TMEM38B,ARHGAP21,VPS4A,GOLGA5,TMCC1,SURF4,VCPIP1,RAB22A,SNX10,PAFAH1B1,STX5,BLOC1S2,LYZL4,DES,RNF26,PLSCR1,ESYT1,RETREG2,YIPF5,EXOC8,AKAP8L,LMAN1,SNAP23,PRKCA,SEC61A1,LAMTOR1,DMPK,PLN,STX6,WDR83OS,UBXN2B,IZUMO1,CCDC42,PLEKHJ1,TRAM1L1,NHERF1,FOLR1,SYP,STX11,TMED9,PLEKHF1,CXCR4,UBL4A,VPS28,EMC6,ARFGEF1,GOLPH3L,NSFL1C,STX1A,CLU,CORO1C,RAB6B,ATL1,FA2H,RAB11A,VMP1,PLSCR4,RAB2A,SPTBN1,UBAP1,VAPB,LPCAT3,CD9,ATG9A,UBE2I,AQP11,SNX3,TRAM2,TMEM127,EMP2,ZMPSTE24,HDAC3,RTN4,VTI1B,COG1,CAV3,PLEKHF2,VPS18,BLOC1S3,OPTN,SNAPIN,RAB1A,CHMP2B,USP8,CHMP2A,TMEM95,CAV1,ATP6V1A,EMC10,FLOT1,RNASEK,SERPINA5,SNAP25,TLCD1,LMNB1,SNAP29,ATP6V1D,AP1S2,USP6NL,ATP6AP2,ROPN1B,TMED1,CDK1,AKT2,RAB18,CDC42,CHMP1A,DEGS1,CAMLG,CREB1,ATP6V0B,SOD1,BANF1,EMC1,RAB3A,REEP4,CRISP1,TOR1AIP2,FHIP1B,VTA1,IZUMO1R,UGCG,RAB27A,SYNGR1,HGS,ACTL9,PRKCB,RETREG3,CAV2,HPS6,TSG101,LYZL6,PTEN,ZNF501,REEP6,VPS4B,PRMT5,FOLR2,TMED4,SNX33,PHETA2,AKT1,RAB1B,LMNA,EMC4,JAGN1,EMC2,SEC22B,RAB29,SNX18,SYNGR2,PACSIN3,PLSCR3,REEP3,AP1M1,CAVIN2,PDCD10 |
| 1.949e-03 | -6.24 | cellular response to mechanical stimulus | biological process | GO:0071260 | 74 | 34 | 18204 | 5365 |
IL1B,CD40,SOX9,GADD45A,IRF1,MYD88,BAG3,BCL10,DAG1,FAS,F11R,TMEM87A,KCNJ2,GCLC,TLR4,ITGA2,PTGER4,ATP1A2,LTBR,TLR5,TLR8,PDE2A,TLR3,MTPN,TLR7,SLC2A1,IL13,BAD,IGF1R,CRADD,BAK1,NFKB1,SLC38A2,MAP3K14 |
| 1.960e-03 | -6.23 | PHACTR4 (phosphatase and actin regulator 4) | protein interactions | 65979 | 106 | 44 | 19454 | 5460 |
RHOG,YWHAB,BCL7C,YWHAH,YWHAG,ARF6,SNRPD3,RHOH,STX6,CAV1,HRAS,RAB35,IFIT2,GJA1,RAC2,RND3,ARHGAP12,KRAS,FLOT1,RAD21,BAG2,IGF1R,LAMTOR1,RHOB,YWHAZ,CSK,RAB11A,TOMM40,DNAJC5,PPP1CC,RHOJ,ACTB,VIRMA,CTNNA1,RAB9B,UBE2I,FGFR1,ARL15,SCLT1,CLDN4,CDC42,STX7,RHOU,RAB5A |
| 1.960e-03 | -6.23 | purine ribonucleotide metabolic process | biological process | GO:0009150 | 373 | 136 | 18204 | 5365 |
ENO1,HTR2A,ACSS2,DLAT,HSPA8,NDUFS8,ATP5F1A,NDUFB10,PNP,NME1,NDUFAB1,GLYAT,ENO2,PDE4B,MPP1,COX11,PDE7A,NDUFA12,NDUFB7,ATP5MC3,SULT1B1,MMUT,NUDT18,HACD2,GMPS,NDUFS2,SUCLG2,GNAI3,ADK,ELOVL3,CASK,RAB23,ATP5PB,FITM2,NUDT4,STOML2,DNAJC30,ACSL4,DLST,SLC25A1,NDUFB6,PGM1,IER3,NDUFV2,NDUFS6,OGDHL,MFN1,NDUFC2,GUK1,RAN,PDE9A,SDHC,NUDT5,PAPSS2,NDUFB8,NUDT7,ELOVL4,ATP5PO,PGK1,LIPA,AK5,GAPDH,DCAKD,HACD1,ELOVL7,AK2,ADSS2,ATP6V1A,ADCY3,HINT1,NDUFB4,AK3,ATP5F1E,NDUFS3,ACOT6,FAR2,NUDT19,HMGCS1,NME4,PGAM1,ABHD14B,EPHA2,OLA1,NDUFA1,LDHA,PPAT,PDE8A,SULT1A3,FKRP,PFKFB2,ATP5MK,PDHB,NME2,NDUFA5,GTPBP1,PPT1,ATP5MG,NT5C2,UQCC3,PDE1A,UCP2,NUDT2,ATP5PD,GPAM,ATP5F1B,NPR2,ENTPD4,TECR,ATP5PF,TPST1,PDHA1,ACAT1,BPGM,NDUFA2,ATP1A2,MVD,ACOT8,DLG1,PTHLH,SDHB,ATP1B1,ELOVL6,PDE2A,NUDT9,NPPC,CLPX,NUDT3,BAD,ELOVL1,ACACA,NDUFB5,ATP5MC1,ATP5F1D,ADCY2,CACNB4,GUCY1B1 |
| 1.967e-03 | -6.23 | positive regulation of tyrosine phosphorylation of STAT protein | biological process | GO:0042531 | 66 | 31 | 18204 | 5365 |
IL3,IL13,GH1,IL23A,IL21,IL6,ARL2BP,OSBP,IFNG,IL12B,IGF1,IL15,JAK2,HCLS1,EPO,CCL5,TNF,TNFSF18,LEP,IL6ST,CSF2,IL2,MIR221,GHR,IL12A,CD40,OSM,KIT,IL4,CSH1,IL18 |
| 1.969e-03 | -6.23 | Gap-filling DNA repair synthesis and ligation in TC-NER | REACTOME pathways | R-HSA-6782210 | 65 | 32 | 10285 | 3229 |
POLD4,RFC2,ERCC3,POLE4,POLR2C,LIG3,CCNH,GTF2H4,PRPF19,RPA2,POLD2,POLR2I,RFC5,CDK7,RPA3,RFC3,POLR2B,EP300,MNAT1,POLR2G,POLR2F,POLE3,PCNA,RFC4,TCEA1,UBB,RPS27A,GTF2H2,POLR2L,GTF2H5,UBA52,POLR2D |
| 1.975e-03 | -6.23 | sex_cord-stromal_tumour | COSMIC cancer mutations | sex_cord-stromal_tumour | 41 | 21 | 16828 | 4835 |
HRAS,KRAS,PIK3R1,IDH1,STK11,SF3B1,BRCA1,IKBKB,TP53,SRSF2,KIT,CTNNB1,IDH2,PPP2R1A,JAK2,PTPN11,CDKN2C,NF2,PIK3CA,DICER1,PTEN |
| 1.990e-03 | -6.22 | RNA polymerase II, holoenzyme | cellular component | GO:0016591 | 75 | 34 | 19108 | 5553 |
ERCC3,GTF2H5,GTF2F2,GTF2A2,TAF2,POLR2I,TAF7,CCNH,POLR2G,POLR2C,SUPT3H,TCEA1,CDK7,POLR2B,POLR2L,GTF2E2,TAF10,POLR2F,GTF2A1,TAF5L,TAF11,TADA3,GTF2F1,GTF2H2,PAAF1,ENY2,GTF2B,TAF9,GTF2E1,GTF2H4,MNAT1,POLR2D,CDC73,SKIC8 |
| 1.996e-03 | -6.22 | RABGAP1 (RAB GTPase activating protein 1) | protein interactions | 23637 | 109 | 45 | 19454 | 5460 |
GJA1,MAP1LC3A,CEBPG,RAB35,STX6,NUF2,HNRNPL,OSBP,DLK2,KXD1,HAX1,TRIM11,IMMP2L,HNRNPF,LSM4,PSMA1,PSMA5,GABARAPL1,KIF2A,POLR2C,APEH,RAB6B,RAB4A,DISC1,SEC61B,SENP5,PHF21A,CD79B,VIRMA,COPE,MANSC1,RAB11A,HSP90AA1,FIS1,HOXC4,LAMTOR1,DDIT3,RAB9A,STX7,KDM1A,RAB6A,RPS14,ATG16L1,KLC2,HSP90B1 |
| 1.996e-03 | -6.22 | CEMIP2 (cell migration inducing hyaluronidase 2) | protein interactions | 23670 | 109 | 45 | 19454 | 5460 |
RAB9A,RAB5A,RHOU,STX7,CLEC12B,ST7,CCL3,CDC42,OTULINL,TMEM106A,RND2,EDDM3B,CLDN4,DNASE1L1,VIRMA,RHOJ,LYZL6,DNAJC5,RAB11A,RAB2A,RHOB,LAMTOR1,SDF2L1,SIAE,RAB3B,KRAS,CBLN4,RAF1,RAB4A,SFTPC,RAC2,GJA1,RAB35,HRAS,CAV1,STX6,DIRAS3,LMAN1,RHOH,ARF6,CD81,LAMP3,LCN6,RAB5C,RHOG |
| 1.996e-03 | -6.22 | ACOT2 (acyl-CoA thioesterase 2) | protein interactions | 10965 | 109 | 45 | 19454 | 5460 |
SLC25A12,RMND1,ARF6,GATD3,AIFM1,SSBP1,MRPS26,TMEM70,CHCHD1,RHOG,GRSF1,MTRF1,IMMP2L,FASTKD5,EPHA4,COX8A,IGF1R,HINT2,CLPB,SFXN1,HSPD1,GFM2,PDHA1,METTL15,AURKAIP1,MRPL11,CCDC90B,MTG1,TACO1,HTRA2,NTRK3,TUFM,PMPCA,MTG2,AUH,CRYZ,SLC25A51,PHB2,GFM1,EXD2,RBM23,NGRN,MTRES1,TIMM29,CNP |
| 1.996e-03 | -6.22 | PALLD (palladin, cytoskeletal associated protein) | protein interactions | 23022 | 109 | 45 | 19454 | 5460 |
TES,TSG101,IGBP1,GSK3A,DSTN,HOMER3,ACOX1,OPTN,DYRK1A,SRPK2,VIRMA,CNTROB,HOMER1,ACTB,SUMO2,PDLIM3,MTPN,H2BC9,YWHAH,WWP2,SFN,MYC,HSPB1,NCKIPSD,FBXW11,BRCA1,EP300,BAG2,PML,RPA3,HSPA5,GRPEL1,TRIM37,STAU1,TOLLIP,G3BP1,ARHGAP12,CDC42,ISG15,TP53,PIH1D1,ITGB5,SCLT1,SKA3,RPA2 |
| 2.002e-03 | -6.21 | LTN1 (listerin E3 ubiquitin protein ligase 1) | protein interactions | 26046 | 193 | 73 | 19454 | 5460 |
MRPL50,RPL7,MRPL24,CHMP2A,SRP14,GTF2B,PTPN1,KRT8,SNRNP70,TPGS2,PPM1B,SKIC8,UBE2D1,FAM174A,RPL6,PRPF19,CENPP,LAMP3,P2RY10,KRAS,SEM1,IRAK4,B3GALT2,PC,IGF1R,JAK1,SIGLECL1,CA14,PLD3,CHRM3,FEN1,KIF2A,TUBB,CEP97,VIRMA,ESR2,NMI,UBE2L3,CD79B,CCNF,SEC61B,MRPL13,IL2RA,PTPMT1,PRMT5,CD226,IVNS1ABP,NTRK3,GPR17,CUL3,MYC,TYW3,MRPL41,NPTN,IRF7,CHMP2B,RNF11,SAP18,DUSP9,SNAPC1,CD40,RPA3,EXOSC4,SSR1,RPA2,ACACA,NICN1,CFTR,NPY2R,AGO1,TIRAP,HCST,GABRA1 |
| 2.006e-03 | -6.21 | C-C chemokine receptor activity | molecular function | GO:0016493 | 23 | 14 | 18094 | 5411 |
ACKR3,CCR3,CCR1,CCR2,GPR75,CX3CR1,CCR4,CXCR1,CXCR3,CCR5,CCR7,CXCR4,CXCR6,CCR6 |
| 2.006e-03 | -6.21 | PLCG1 (phospholipase C gamma 1) | protein interactions | 5335 | 258 | 94 | 19454 | 5460 |
ATP5F1A,MTPN,AR,AGAP2,AKT1,PTPN11,NCKIPSD,UBE2H,GAB1,CCNF,SRC,RAPGEF5,PRKCE,GTF3C4,MET,PITPNA,LMNA,RPA2,PTP4A2,PICALM,FGFR1,RPA3,RHOU,PML,SNX11,HSPA5,GRAP,SNAP91,COPS5,SHC1,CACNB3,ADD1,SEC23A,ITK,SYNCRIP,LCP2,CD28,CAV1,EEF1A1,UBR7,TP53,SPRY1,PIK3CA,DISC1,SOS2,NTRK2,DDR1,EHD4,HNRNPK,RNF40,BAG3,COPS7A,MYC,RAB11A,NTRK3,JAK2,DYNLL1,SYK,FEM1A,RNF7,EP300,DNAJC3,DUSP9,PYGB,UNC45A,HSCB,SRSF2,STAU1,MCMBP,LAT2,CISH,PIK3R1,CBL,SKIC8,NCK1,XPO5,COPS2,WDR6,NTMT1,HSP90AB1,COPS7B,HNRNPL,AASDHPPT,ATXN10,TOP3B,ERRFI1,HEXA,GHR,LDLRAD4,JAK1,NUDT5,COPS4,KIT,ROCK2 |
| 2.018e-03 | -6.21 | ACAA1 (acetyl-CoA acyltransferase 1) | protein interactions | 30 | 69 | 31 | 19454 | 5460 |
ACAT1,SF3B4,ENO1,MRPL53,ACOX1,TRMT6,TENT5C,RPL35A,CFL1,AK3,PPIB,SUGP1,PRDX1,HTRA2,CDK12,AGR2,TFPT,IMMP2L,SRPRB,CRYL1,ARHGEF39,CAMK2G,GTF2E2,NDUFA2,TIMM10,EIF1AX,PDHA1,HBB,ACAA2,FEM1A,TFCP2 |
| 2.026e-03 | -6.20 | retroperitoneum | COSMIC cancer mutations | retroperitoneum | 31 | 17 | 16828 | 4835 |
MAX,MAP2K1,GNAQ,IDH1,PIK3R1,KRAS,HRAS,EZH2,PIK3CA,CD79B,IDH2,AKT1,PTPN11,JAK2,CTNNB1,MET,KIT |
| 2.028e-03 | -6.20 | negative regulation of glucose transmembrane transport | biological process | GO:0010829 | 21 | 13 | 18204 | 5365 |
GSK3A,PRKCB,MIR107,GRB10,LEP,SELENOS,MIR143,PEA15,TNF,INPP5K,IL1B,PID1,FABP5 |
| 2.028e-03 | -6.20 | regulation of glial cell migration | biological process | GO:1903975 | 21 | 13 | 18204 | 5365 |
MIR221,TIAM1,CCL3,CCR2,CX3CR1,P2RY12,RRAS2,MIR222,STAP1,CRKL,BMERB1,CX3CL1,CERS2 |
| 2.029e-03 | -6.20 | TSC22D4 (TSC22 domain family member 4) | protein interactions | 81628 | 112 | 46 | 19454 | 5460 |
YWHAZ,FBXW11,NIF3L1,LMO2,GORASP2,CCDC42,MAD2L1,IFT172,P3H1,CKS2,PIH1D1,MYLIP,UBLCP1,FBXW7,FXR2,CLU,SAT1,P4HA2,CRTAP,TTL,SMG8,CDC23,ELOC,YWHAH,HNRNPA1,YWHAG,TSC22D3,PRNP,HNRNPL,LANCL1,LRWD1,AIFM1,SMAD3,WDR6,MTHFS,PCDH17,MAD2L1BP,SMARCB1,CDK5R1,KPNA2,TRIM63,NOC4L,PSMA1,ENKD1,CA10,RIGI |
| 2.029e-03 | -6.20 | MTMR14 (myotubularin related protein 14) | protein interactions | 64419 | 112 | 46 | 19454 | 5460 |
CCNF,GPX1,NPPC,IDE,CUL2,BICD2,FAS,UBE2H,OSGEP,PEBP1,RAB5A,GPX4,UFL1,HSCB,GABARAP,AKR7A2,ELK4,CFTR,RPA2,CAV2,SDHB,ACSL4,AASDHPPT,ATXN10,EGLN3,TMPO,PADI2,GMPPA,ACOT8,ATG9A,XPO1,SHC1,SMAD4,CDKN2C,PDIA6,FN3KRP,MAPK1IP1L,CDK4,TP53,TOP3B,PPP2R1A,TRAF2,MAP1LC3B,BPIFB1,MTA2,GNB1L |
| 2.037e-03 | -6.20 | PRKCD (protein kinase C delta) | protein interactions | 5580 | 227 | 84 | 19454 | 5460 |
TP53,RAF1,EEF1A1,PPARA,SOX2,NFE2L2,PLS3,PIK3CA,GNAZ,TRAPPC13,BCKDK,PLSCR1,PLCB1,IGF1R,RASGRP3,HNRNPK,DHX16,CAMK2G,ADD2,PTGES3,LAMP2,YWHAG,ATG7,TRAF6,TIAM1,SHC1,IKBKB,HSPB1,YWHAB,SDC4,PHB1,ACTA2,ITGA6,ADD1,SNX1,PLSCR3,EIF2S1,CWC15,ZBTB2,PRKCQ,H1-5,CNP,GABRA1,IL6ST,SEC62,PDP2,RPA2,KLF4,PRKCA,CD34,PEBP1,EP300,AKAP1,SQSTM1,HDAC5,PRKCB,STAU1,ADRB2,RANBP10,PYGB,AKT3,MYC,CREBBP,RHOB,LMNB1,TLR9,YWHAZ,FAS,BLVRA,H1-1,HSP90AA1,SP1,SEC61B,CYTH1,GSK3A,RPL37A,PRKCE,MED17,ACTB,KCTD9,STAT1,SRC,IDE,TOM1L1 |
| 2.039e-03 | -6.20 | SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1) | protein interactions | 56916 | 187 | 71 | 19454 | 5460 |
MAD2L1,NOPCHAP1,MATR3,SNRNP40,ANAPC2,PELP1,DOK4,CPSF1,ZNF330,EPHA2,DNAJB6,LMNB1,RFC5,SMARCE1,NONO,CPSF2,DNAJC8,SMARCA5,MYC,CDC16,CUL3,COIL,KDM1A,RPL4,DDX5,HELLS,RFC4,RPA3,XRCC5,E2F6,RPA2,GTF3C4,CDK7,ACTL6A,SUMO1,TMPO,CDC5L,CEP19,HNRNPL,SNRPD3,SUMO2,SIN3A,EEF1AKMT3,FUBP3,SRSF1,CDC23,HNRNPD,TOPBP1,CSNK2A1,PRPF19,ZNF24,PDE2A,GTF3C3,RFC2,MSH6,RFC3,SSRP1,HUWE1,HNRNPK,RUVBL1,PCNA,RUVBL2,RING1,DHX9,RBPJ,SMARCB1,MTA2,DMAP1,CBX3,MTA3,ANP32A |
| 2.039e-03 | -6.20 | BAIAP2 (BAR/IMD domain containing adaptor protein 2) | protein interactions | 10458 | 187 | 71 | 19454 | 5460 |
YWHAZ,RHOB,BICD2,PKNOX1,NRP1,NCKIPSD,NTRK3,GRB10,SFN,EPS8,LIN7B,AKT1,DNAJC5,ARL6IP6,ACTB,RHOJ,DAPK1,NCKAP1,ESR2,SRPK2,DLG4,CCNF,SF3B4,FGFR1,CSNK1G3,TFB1M,ARL15,PRR13,CLDN4,H1-5,CDC42,STAU1,KDM1A,CYFIP2,STX7,ZDHHC17,GID4,LIN7C,RHOU,DDX39B,RTN4,CRY1,HSPA8,NCK1,RHOG,YWHAB,ARMC8,WWP2,DPP4,YWHAG,YWHAH,HDAC6,RHOH,HNRNPL,KCTD3,STX6,HRAS,RAB35,RAC2,NHERF1,ACTR2,NUPR1,NDUFA12,CSNK1E,RAF1,WASL,KRAS,EPHA4,CAMK2G,PDE2A,ERG28 |
| 2.040e-03 | -6.19 | TLR4 Signaling and Tolerance | WikiPathways | WP3851 | 30 | 19 | 5310 | 1910 |
TNF,IRF3,TIRAP,TRAM1,IRAK4,MYD88,NFKB1,TLR4,TRAF6,IKBKB,TAB2,IL6,IRF7,TICAM1,CXCL8,TBK1,TAB1,NFKBIA,IFNB1 |
| 2.041e-03 | -6.19 | lobular_carcinoma_in_situ | COSMIC cancer mutations | lobular_carcinoma_in_situ | 36 | 19 | 16828 | 4835 |
KIT,GNA11,MET,CTNNB1,TP53,PTPN11,JAK2,AKT1,IDH2,FBXW7,FGFR1,PIK3CA,NTRK3,HRAS,KRAS,PIK3R1,IDH1,GNAQ,MAP2K1 |
| 2.041e-03 | -6.19 | breast-carcinoma_in_situ-lobular_carcinoma_in_situ | COSMIC cancer mutations | breast-carcinoma_in_situ-lobular_carcinoma_in_situ | 36 | 19 | 16828 | 4835 |
NTRK3,PIK3CA,FGFR1,IDH2,FBXW7,JAK2,PTPN11,AKT1,TP53,MET,GNA11,KIT,CTNNB1,MAP2K1,GNAQ,PIK3R1,IDH1,HRAS,KRAS |
| 2.045e-03 | -6.19 | RPIA (ribose 5-phosphate isomerase A) | protein interactions | 22934 | 58 | 27 | 19454 | 5460 |
NIF3L1,IVNS1ABP,NTAQ1,HSPB8,GORASP2,GMPS,MOV10,CENPP,PTPN11,DUSP3,FBXO22,RNF208,STK16,SDCBP,DDX39A,RPE,DDIT4L,WDR5B,TXNRD1,VTA1,FOXP2,FXR2,KRAS,HSCB,RPIA,PICK1,ATPAF2 |
| 2.045e-03 | -6.19 | P2RY12 (purinergic receptor P2Y12) | protein interactions | 64805 | 58 | 27 | 19454 | 5460 |
CRELD1,PALS2,GOLGA5,YIPF3,ATP5PB,CERS6,SACM1L,CMTM6,PTRHD1,TSPAN15,TMEM164,FITM2,BLVRA,GEMIN8,VKORC1L1,ATP5PD,CAV1,ACP2,TNPO3,RMND1,GNAI2,ARL6IP5,ATP5F1B,LGALS3,SLC30A7,GPR89A,ARL10 |
| 2.045e-03 | -6.19 | RIOX1 (ribosomal oxygenase 1) | protein interactions | 79697 | 58 | 27 | 19454 | 5460 |
MRPL24,VIRMA,ESR2,RPL10,RPL8,CCNF,PHB1,SEC61B,SDF2L1,MYC,RPL7A,NPM3,CHCHD2,ADRB2,MRPL41,RPL4,RPL3,MTDH,RNF113A,EZH2,HBP1,RPLP0,MLLT11,RAF1,WDR77,MRPL47,AURKAIP1 |
| 2.046e-03 | -6.19 | ribonucleoprotein granule | cellular component | GO:0035770 | 271 | 101 | 19108 | 5553 |
ACTB,YTHDF1,ROCK2,DDX4,RPL6,PIWIL2,POLDIP3,TRIM21,USP3,PQBP1,PABPC1L,STAU1,TDRD7,NUFIP2,TIA1,ANKRD34B,PIWIL4,LSM2,DCP2,CDK9,TUBA1A,YTHDF2,TAF5L,G3BP1,UHMK1,GRSF1,PSMA4,CNOT2,DDX1,LSM3,APOBEC3G,INA,MCRIP2,EIF4E2,HNRNPL,LARP4B,MAEL,EID1,SUMO1,DYNC1I1,LSM14A,HNRNPK,G3BP2,CDC42,APOBEC3H,CMA1,CARHSP1,RC3H2,PABPC1,LSM6,TOP1,HAX1,CIRBP,LSM4,RPLP0,PNRC1,PSMA6,APOBEC3A,RPL28,SERPINB1,ISG20,TRIM5,EIF4E,APOBEC3B,POLR2G,PIWIL1,CASC3,CNOT8,CPEB1,EIF4EBP2,MOV10,HENMT1,AGO1,TUBB,ROCK1,PSMA2,EIF2S1,GHR,APOBEC3F,FASTKD5,FXR2,SNRPB2,PIWIL3,SNRPG,RPS4X,EDC3,ASZ1,GABPB1,PABPC5,IGF2BP1,PSMC3,MYH1,DHX9,GARRE1,APOBEC3C,CNOT7,SQSTM1,APOBEC3D,C9orf72,SMN1,TNRC6C |
| 2.050e-03 | -6.19 | HIBADH (3-hydroxyisobutyrate dehydrogenase) | protein interactions | 11112 | 86 | 37 | 19454 | 5460 |
TXNDC17,SOD1,PAEP,SFT2D2,TRIM63,HSCB,TMEM60,ZNF692,CDK7,UBIAD1,HEXA,GOSR2,AGTRAP,SEC22B,TMEM14B,CRELD1,CMTM7,AQP3,CTSA,ACAA2,VAMP2,TFRC,TES,MGME1,COMT,AIG1,EFNA5,LDHA,GPX1,RNASEH1,PGAM1,VAMP5,MDH1,C2CD2L,PLN,CHCHD4,BRCA1 |
| 2.050e-03 | -6.19 | CCR6 (C-C motif chemokine receptor 6) | protein interactions | 1235 | 86 | 37 | 19454 | 5460 |
ATP5PB,FUT8,CCL20,SLC19A2,SLC29A1,YIPF3,ABCB1,LMBRD2,GOLGA5,POMT2,TMEM184B,TSPAN3,TMEM87A,ATP2C1,ATP2B4,RINT1,TSPAN15,RRAGB,RER1,DAD1,SACM1L,CERS6,LPCAT3,HM13,SLC30A5,DOLK,FITM2,DEFB1,ELOVL4,SLC39A10,MFSD5,SERINC1,MCOLN1,GPR89A,SPPL3,DERL2,RMND1 |
| 2.050e-03 | -6.19 | PTDSS2 (phosphatidylserine synthase 2) | protein interactions | 81490 | 86 | 37 | 19454 | 5460 |
P2RY12,AQP3,DRD3,STOM,GPR35,B3GALT4,CCDC47,H2AJ,TP53,OTULINL,LPAR1,HS2ST1,MRGPRX4,TSPAN15,RPAP3,LPAR2,TACR1,VIPR1,SYP,P2RY1,FKBP4,AHSA1,HSP90AA1,H2AC14,CCR6,APLNR,RAMP3,HSP90AB1,OPRL1,CCNF,S1PR4,LMBR1L,RETREG3,EDNRA,STARD3NL,GPR173,SLC1A1 |
| 2.050e-03 | -6.19 | FAM171A1 (family with sequence similarity 171 member A1) | protein interactions | 221061 | 86 | 37 | 19454 | 5460 |
RND2,CDC42,FGFR1,RND3,DDR1,NTRK2,IGF1R,EPHA4,KRAS,FLOT1,STX7,SFN,CIAO1,DNAJC5,YWHAH,YWHAG,RHOB,MYO6,YWHAZ,LAMTOR1,RHOG,YWHAB,STYK1,NTRK3,EPHA2,RAB35,RAC2,NRSN1,GJA1,TMEM74,DYNLL1,RHOJ,RHOH,SPPL3,VIRMA,CAV1,EGLN3 |
| 2.050e-03 | -6.19 | PREP (prolyl endopeptidase) | protein interactions | 5550 | 86 | 37 | 19454 | 5460 |
BAP1,HSPD1,RPA3,GLUL,SIRT7,PABPC1,PSME1,CSE1L,RUVBL1,HNRNPDL,PPP1R8,EHD1,MAP1LC3B,SOX2,RPA2,STX17,GDI2,LACC1,AIP,CTTN,CAND1,SNRPD3,ADRM1,TAC1,CACYBP,DHX15,MTG2,PRDX1,PTDSS1,ISYNA1,XPO1,GLO1,SMAD4,BRCA1,OAT,DNAJC7,SERPINH1 |
| 2.053e-03 | -6.19 | negative regulation of MAPK cascade | biological process | GO:0043409 | 170 | 68 | 18204 | 5365 |
DUSP26,BTN2A2,SPRY1,EMILIN1,ATF3,TLR4,STK38,SMAD4,DUSP10,PTPN22,MIR205,ZMYND11,IL1B,RGS2,DAG1,PTPN1,INPP5K,SYNJ2BP,CSK,HYAL2,GSTP1,IGF1R,FLCN,PDCD4,MYC,DUSP1,PHB1,DUSP19,PPIA,SPRED2,ADIPOQ,SPRED1,PAFAH1B1,MIR133B,MIR185,DUSP3,EPHA4,CRYBA1,MIR503,MIR221,PPARG,LMO3,MIR218-1,PAQR3,IGBP1,LILRB4,DLG1,MIR21,MIR20A,HDAC3,CNKSR3,PIK3R2,DUSP9,TLR9,FKTN,PEBP1,CDK5RAP3,CAV3,DEFB114,MIR424,TBC1D10C,NF2,NLRP6,DUSP6,CAV1,PSMD10,MIR200C,NHERF1 |
| 2.058e-03 | -6.19 | DOCK8 (dedicator of cytokinesis 8) | protein interactions | 81704 | 115 | 47 | 19454 | 5460 |
ATP5PO,CARHSP1,FAM161A,SF3A1,MED30,CDC42,PRDX3,PFKFB2,TMEM263,APPBP2,PGK1,MYO6,CKB,CRLF3,SMAD2,LDHB,BAG3,MCM3,RHOJ,TAGLN2,LDHA,MTG1,OPTN,ACAT1,MRPS28,ARPC3,PDHA1,RPN1,ANP32A,ZNF581,HSPE1,RUVBL1,KRAS,RPS27A,SRSF8,SEPTIN7,SNRNP70,NME2,COX5A,PDIA3,PPIB,XPO1,CHMP2A,CDC5L,HRAS,S100A8,MAGED2 |
| 2.058e-03 | -6.19 | ASCC2 (activating signal cointegrator 1 complex subunit 2) | protein interactions | 84164 | 115 | 47 | 19454 | 5460 |
ASCC1,SNRPB,FBXO22,SMURF1,ESR2,CCNF,RPS3,RPS20,RPL26L1,TBC1D17,MED31,ALKBH3,PABPC5,GPC4,HSCB,KDM1A,STAU1,CSRP1,POLA2,RNF11,POLDIP2,NOG,SMAD4,DRG1,DDRGK1,PAIP1,RPS10,CGAS,FUNDC2,PRPF18,EEF1AKMT3,RPLP1,RPS11,GTPBP1,TBK1,RAF1,FBP1,SPC24,URM1,TULP3,OLA1,RPS13,FAF1,TRIP4,KATNAL1,GADD45A,EMC2 |
| 2.060e-03 | -6.18 | negative regulation of glycoprotein metabolic process | biological process | GO:1903019 | 28 | 16 | 18204 | 5365 |
MIR20A,ITM2A,MIR17,AATF,CST3,MIR31,MIR144,MIR455,MIR101-1,MIR298,MIR106A,ITM2B,MIR147A,MIR153-1,ACOT8,HBEGF |
| 2.060e-03 | -6.18 | protein exit from endoplasmic reticulum | biological process | GO:0032527 | 28 | 16 | 18204 | 5365 |
SURF4,SYVN1,SEC13,HM13,SELENOS,ERLEC1,DERL1,FAF2,TMED9,RANGRF,LMAN1,UFD1,SEC61B,OS9,DERL2,HSP90B1 |
| 2.090e-03 | -6.17 | YIPF3 (Yip1 domain family member 3) | protein interactions | 25844 | 178 | 68 | 19454 | 5460 |
NDUFC2,SYVN1,VIPR1,TACR1,MGAT4B,RETREG2,CXCR4,SLC5A6,GPM6A,SLC19A2,GINM1,SYNGR2,PIGW,CAV2,FAM8A1,GOLGA5,STOM,SIGMAR1,GPR35,P2RY12,GPR173,GPR89A,SLC1A1,ADGRL3,SYNGR1,CHRM4,NIPA2,LMBR1L,S1PR4,SEC63,APLNR,REEP4,SC5D,MCM3,CAV3,OPRM1,RAB2A,SYCE3,NDUFB6,OXTR,ENDOD1,LPAR2,BSCL2,GPAA1,NDUFB5,PLSCR1,SLC6A8,B4GALT7,SLC7A14,YIPF4,MAP1LC3B,CHRM3,NDUFA12,PTRH2,SURF4,MFSD5,PHB1,CD63,SLC43A2,CAV1,TLCD4,LMAN1,SPPL3,CCR6,RAB5C,EI24,NDUFB8,P2RY1 |
| 2.090e-03 | -6.17 | PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) | protein interactions | 5290 | 178 | 68 | 19454 | 5460 |
CTNNB1,YWHAH,HDAC6,DPY30,PIK3R1,NFKB1,TNFSF13,CBL,TRAF6,MRAS,GJA1,HRAS,IL3,SMAD3,CAV1,CDK9,CD28,RHOH,EEF1A1,DDX39A,E2F4,FASLG,GNAI3,GNAQ,BPIFB1,GALNT12,CDK5,MYO1B,CYTH2,TICAM1,RASGRP3,KRAS,KIT,UFD1,PTPN11,PIK3R3,MYC,AKT1,DNAJB6,STK11,SMAD2,PTTG1,TXNIP,RPS20,TMEM74,RPS3,GNB1,VIRMA,SFRP4,MANSC1,UMPS,STAT1,RAPGEF5,PAQR3,PRKCA,TMOD1,AVPR1B,MAP2K1,FBP2,DDX5,SQSTM1,DERL1,ATP5IF1,ABCB9,CD40,FTL,PIK3R2,SLC31A1 |
| 2.093e-03 | -6.17 | regulation of myeloid leukocyte differentiation | biological process | GO:0002761 | 127 | 53 | 18204 | 5365 |
HAX1,FBXW7,TESC,CDK6,GPR137,TLR4,CCL3,PPP3CA,KLF10,LILRB1,C1QC,CTNNB1,TNFAIP6,MYC,MITF,CREB1,SFRP1,MIR145,BGLAP,NOTCH2,FOXP1,TNF,ADIPOQ,MIR223,TLR3,IL12B,IFNG,EEIG1,CARTPT,TRIB1,CTNNBIP1,CD4,INHA,LILRB4,PRKCA,PIK3R1,RUNX1,TCTA,TRAF6,IL4,NDFIP1,IL23A,TOB2,CCR1,TFE3,UBASH3B,RB1,IL5,IRF7,TYROBP,FOS,HCLS1,IL34 |
| 2.101e-03 | -6.17 | LUCAT1 (lung cancer associated transcript 1) | protein interactions | 100505994 | 15 | 10 | 19454 | 5460 |
YWHAG,EEF1A1,CALML5,UBA52,ENO1,PRDX1,HSPB1,RPS5,ACTB,H1-6 |
| 2.101e-03 | -6.17 | DBP (D-box binding PAR bZIP transcription factor) | protein interactions | 1628 | 15 | 10 | 19454 | 5460 |
TEF,RIGI,DDX39A,HLF,CEBPG,EP300,DDIT3,IFI16,ATF3,BATF |
| 2.101e-03 | -6.17 | NBEAL1 (neurobeachin like 1) | protein interactions | 65065 | 15 | 10 | 19454 | 5460 |
HNRNPA1,KIF1C,ATG9A,VIRMA,RGMA,AP1S2,CNTROB,PRNP,NPTN,SDC2 |
| 2.106e-03 | -6.16 | POC1A (POC1 centriolar protein A) | protein interactions | 25886 | 121 | 49 | 19454 | 5460 |
KCTD10,MAPRE2,TCP1,NOB1,CCT7,SLAIN2,FAAP100,NELL2,ECD,FKBP4,BGLAP,TUBG1,RASSF8,PFDN5,INSYN1,KHDC1,AHCYL1,SIAE,PFDN1,CCT8,PPP1R12A,POC1B,RPAP3,IFT57,SKA3,TAF2,SUPT5H,CCT5,SNAPC5,TOP3B,ENO2,PELO,WDR45,CCT2,CKB,PFDN6,PFDN4,PFDN2,FGFR1OP2,BTF3,FTL,UNC45A,CORO6,COMMD2,HSPA8,PDCL,FAM161A,SAP30BP,AKIP1 |
| 2.108e-03 | -6.16 | VPS35 (VPS35 retromer complex component) | protein interactions | 55737 | 249 | 91 | 19454 | 5460 |
RNF8,TMEM165,CAPZA2,DRD1,H2AX,CENPM,CAPZA1,TOLLIP,TTC4,EMC2,MUL1,RPL24,HDAC6,MOV10,KXD1,IRF4,EMC4,CITED1,DNAJC1,LDLR,ETV6,RPA2,HSP90B1,GRPEL1,FBXW7,RPA3,BAP1,SNX5,CRLF3,IVNS1ABP,LRRC73,CEP97,SNX3,SLC11A2,SNX12,CCNF,ENO1,HGS,EZH2,PNMA2,JUN,SOX2,PPP2R1A,SPG21,KIF2A,MSX2,RAF1,HS2ST1,DCP2,KRAS,GNL1,VPS26B,GPSM3,CBL,ANKRD50,TBC1D5,LAMP2,HMGA1,PRPF19,VPS26A,VAMP7,TRMT61A,NOB1,SNX1,SNX2,CORO1C,ATP6V1A,PHB1,EIF4B,FKBP10,CSNK1A1,MMP14,ATP6V1C1,EMC1,UFL1,ADRB2,PMAIP1,EP300,RAB5A,LCA5,COMMD9,BRCA1,RIOK2,MYC,NIBAN2,SSH3,FBXO22,VEGFA,TRMT6,S100A6,LMBR1L |
| 2.108e-03 | -6.16 | KMT2A (lysine methyltransferase 2A) | protein interactions | 4297 | 249 | 91 | 19454 | 5460 |
E2F6,RPLP0,RPA2,KLF12,CXXC1,MBD3,FBXW7,NUCKS1,SIRT7,PML,HCFC2,RPA3,CDC73,TADA3,AR,RUNX1,VIRMA,SRC,RPL13A,YES1,BUB3,PTEN,FGFBP1,PRKRA,CSNK2B,ZNF330,CBX3,TP53,H3C1,RPL3,BRD3,TAF9,H2AC4,ZMYND11,ELOC,CSNK2A1,CDK9,TOP1,LDLR,KRR1,PIH1D1,CKS2,KLF3,CTBP1,NUP50,SP1,YWHAZ,KANSL3,SFN,CREBBP,MYC,ESR2,APEX1,FBXO22,RBBP4,MED17,SNRNP40,MTM1,RPS9,RAN,IRF2,SMARCB1,RBPJ,EZH2,ELF1,SAP30,LGR4,SOX2,E2F4,SUPT5H,FASLG,CKS1B,SSRP1,RERE,SRSF4,RUVBL1,ASF1A,RBBP7,KRAS,EWSR1,YWHAB,ASB7,AGR2,SKIC8,CTNNB1,YWHAH,YWHAG,DPY30,WDR82,SIN3A,CBFB |
| 2.113e-03 | -6.16 | DUX4L9 (double homeobox 4 like 9 (pseudogene)) | protein interactions | 100288711 | 42 | 21 | 19454 | 5460 |
CCT7,DES,ARF4,RPS4X,TCP1,RPL4,PRDX2,LDHA,DDX5,FHL3,ACTA2,MYH2,RPS3,VDAC2,RPS2,HSP90B1,CCT2,LDHB,CCT5,NDUFB10,PRDX1 |
| 2.113e-03 | -6.16 | SFT2D1 (SFT2 domain containing 1) | protein interactions | 113402 | 42 | 21 | 19454 | 5460 |
SCN3B,SPG21,HACD2,SDCBP,SCAND1,STOM,CDR2,OTULIN,TSPAN3,TMEM14B,VAMP3,HRAS,TMX2,RABAC1,RETREG3,ARFIP1,KRAS,REEP4,DERL2,SNX1,MYG1 |
| 2.113e-03 | -6.16 | NSMAF (neutral sphingomyelinase activation associated factor) | protein interactions | 8439 | 42 | 21 | 19454 | 5460 |
PFDN2,HEXIM1,CCT2,JUP,ATG7,FBXL19,GABARAPL1,MAP1LC3B,CCT5,DUSP14,CCT7,RIGI,LYG2,ACTB,TCP1,HNRNPL,MAP1LC3A,PREP,CCT8,NEK9,CD40 |
| 2.113e-03 | -6.16 | E7 (early protein) | protein interactions | 1489425 | 42 | 21 | 19454 | 5460 |
RPL3,TRUB1,PCNA,SPCS2,RB1,PSMB1,STX8,ACKR3,ENO1,PML,MT2A,CLU,MIF,EEF1A1,IGFBP3,MYC,SPTBN1,HNRNPAB,MAP1S,ZNF574,PDLIM4 |
| 2.113e-03 | -6.16 | KMT5C (lysine methyltransferase 5C) | protein interactions | 84787 | 42 | 21 | 19454 | 5460 |
GTF2I,TOP1,MEPCE,PPP1R10,CBX5,FTL,FAM76B,WDR82,RPL23A,POC1B,RB1,TOX4,CBX3,NUFIP2,TOP3B,SAP30BP,EEF1A1,JUN,RPL29,SPRR1B,NONO |
| 2.113e-03 | -6.16 | CRAT (carnitine O-acetyltransferase) | protein interactions | 1384 | 42 | 21 | 19454 | 5460 |
SLC25A10,ACOX1,COX4I1,HINT2,HSPA8,RASL10B,FBXL4,SPTBN1,MRM2,PFDN5,ETFBKMT,PTDSS1,H2BC9,CBR4,SPATA2,SMAD4,ACAA2,NPSR1,CAPZA2,SLC25A20,NUDT16 |
| 2.113e-03 | -6.16 | CENATAC (centrosomal AT-AC splicing factor) | protein interactions | 338657 | 42 | 21 | 19454 | 5460 |
SNRPG,G3BP1,KRAS,HNRNPL,HNRNPF,SNRPD3,ZMAT5,PRPF4,KLC2,PIM2,SNRPE,SART3,RIT1,DCAF5,SKA3,ATG3,YWHAZ,SMNDC1,WDR83,PPIL3,RBM17 |
| 2.113e-03 | -6.16 | ATP6V1C2 (ATPase H+ transporting V1 subunit C2) | protein interactions | 245973 | 42 | 21 | 19454 | 5460 |
METTL15,HPCAL1,ACTL6B,ATP6V1E2,MYC,ATP6V1C1,ATP6V1D,HECTD1,CCR1,PDCD10,STK24,ATP6V1A,HAPSTR1,KLHL24,VAMP3,MRPS9,PAX6,ATP6V1G1,ATP6V1G2,VRK1,TTC9C |
| 2.113e-03 | -6.16 | DOP1B (DOP1 leucine zipper like protein B) | protein interactions | 9980 | 42 | 21 | 19454 | 5460 |
RPA2,MUL1,SDC2,RAB4A,ATP1A1,NRP1,STK16,LAMP2,RAB11A,YWHAH,LAMP3,MGARP,ATP5F1B,NPTN,RAB3B,ESR2,VIRMA,HAPSTR1,RAB5A,MTDH,RAB9A |
| 2.113e-03 | -6.16 | JPT1 (Jupiter microtubule associated homolog 1) | protein interactions | 51155 | 42 | 21 | 19454 | 5460 |
CCNB1,PSMC4,CFL1,TUBA1A,RPA2,HSPB1,COTL1,MOB3C,OTX2,PML,SNCG,RPA3,BAP1,HSPA8,STAU1,KPNA2,PRNP,CPLX1,CAV1,APEX1,SAR1B |
| 2.115e-03 | -6.16 | Signaling by FGFR2 in disease | REACTOME pathways | R-HSA-5655253 | 43 | 23 | 10285 | 3229 |
PIK3R1,FGF16,FGF1,FGF7,POLR2C,FGF23,GAB1,HRAS,PIK3CA,GTF2F1,POLR2I,FGF3,FGF10,FGF17,POLR2B,NCBP2,POLR2G,KRAS,GTF2F2,POLR2F,POLR2D,POLR2L,FGF22 |
| 2.121e-03 | -6.16 | Ruvbl1 (RuvB-like AAA ATPase 1) | protein interactions | 56505 | 89 | 38 | 19454 | 5460 |
MORF4L1,INO80E,ZNHIT3,ECD,PFDN6,PFDN2,ZNHIT6,VPS72,CCNF,WDCP,POLR3B,NOP58,NOPCHAP1,POLR2B,ACTL6A,ZNHIT1,CFTR,RPAP2,CHMP1A,DMAP1,SURF4,PIH1D1,TTI2,TMEM263,TFPT,NDUFB5,STK26,INO80C,RUVBL2,RPAP3,ATP5F1E,DNAAF10,CHMP1B,PAK1IP1,TSSC4,AATF,PDRG1,PSMC1 |
| 2.121e-03 | -6.16 | RAI1 (retinoic acid induced 1) | protein interactions | 10743 | 89 | 38 | 19454 | 5460 |
H2BC9,AR,HMGA1,BRD3,TOPBP1,PDAP1,H2AC4,H2AZ1,ZNF330,VIRMA,MAD2L2,ESR2,NUP35,HMG20A,APEX1,HNRNPL,TOP1,RBBP4,FBXO22,CDKN1A,TOP3B,E2F4,CSNK1A1,RPA2,LMNA,TRIM68,RPL3,HAPSTR1,NUP50,DDIT3,TESC,SIRT7,GADD45A,SSRP1,TTR,VRK1,NUCKS1,ASF1A |
| 2.125e-03 | -6.15 | IRS-related events triggered by IGF1R | REACTOME pathways | R-HSA-2428928 | 298 | 117 | 10285 | 3229 |
PAQR3,STRADB,MET,PSMA5,FGF23,EIF4E,TLR9,PPP2R5E,SPTAN1,PSMB3,PEBP1,PIK3R2,IL2RG,YWHAB,PPP2R5A,FGF1,DUSP6,RAP1B,KRAS,MAP2K1,WDR83,UBA52,FGF22,RAF1,PSMD10,FRS3,DUSP9,SRC,FGF10,IL5,HRAS,GAB1,PPP2CB,KIT,LAMTOR2,PSMB2,PSMD1,PEA15,AKT1,PSMA6,PIK3CA,FGF16,LAMTOR3,CAMK2G,IL2RB,VWF,PSMC1,PRKAG1,CUL3,PSMC3,PSMA1,IL3,RPS27A,SPRED1,PHB1,PSMD4,RASGRP3,SHC1,PSMB4,SEM1,DUSP1,PRKAB1,PSMA4,PSMB10,FGFR1,IL2,PSMC5,PSMB11,PSMA2,PSMB6,BRAP,CSK,RHEB,DLG4,PSMB7,JAK2,PSMD3,PSMB1,PIK3R1,PSMA3,PSMB5,PSMC4,PSMD14,PTPN11,STK11,IGF1,PPP2R1A,UBB,PPP5C,SPTBN1,ANGPT1,PSME1,FGF17,PSMD7,EIF4B,AKT2,SHC3,RRAGA,RAP1A,CAB39,CSF2,FGF7,LAMTOR1,JAK1,PSMD12,MAP3K11,RRAGB,NEFL,DUSP10,IGF1R,PSME2,FGF3,HBEGF,PSMD6,IL2RA,SPRED2,PSMB9 |
| 2.125e-03 | -6.15 | IGF1R signaling cascade | REACTOME pathways | R-HSA-2428924 | 298 | 117 | 10285 | 3229 |
PSMA1,PSMC3,SPRED1,PSMD4,PHB1,IL3,RPS27A,PSMB4,RASGRP3,SHC1,DUSP1,PRKAB1,SEM1,IL5,GAB1,HRAS,LAMTOR2,KIT,PPP2CB,PEA15,AKT1,PSMA6,PIK3CA,PSMD1,PSMB2,CAMK2G,LAMTOR3,IL2RB,FGF16,PSMC1,CUL3,PRKAG1,VWF,KRAS,MAP2K1,RAP1B,RAF1,WDR83,UBA52,FGF22,DUSP9,SRC,PSMD10,FRS3,FGF10,PSMA5,FGF23,PAQR3,MET,STRADB,PSMB3,PEBP1,TLR9,EIF4E,PPP2R5E,SPTAN1,PIK3R2,IL2RG,PPP2R5A,FGF1,DUSP6,YWHAB,MAP3K11,NEFL,DUSP10,IGF1R,RRAGB,HBEGF,PSMD6,PSME2,FGF3,IL2RA,SPRED2,PSMB9,EIF4B,AKT2,RAP1A,RRAGA,SHC3,CSF2,CAB39,PSMD12,FGF7,JAK1,LAMTOR1,PTPN11,PSMD14,PPP2R1A,UBB,STK11,IGF1,ANGPT1,PSME1,PPP5C,SPTBN1,FGF17,PSMD7,PSMB10,FGFR1,IL2,PSMC5,PSMB11,PSMA4,BRAP,CSK,RHEB,DLG4,PSMB6,PSMA2,PSMB1,PIK3R1,JAK2,PSMB7,PSMD3,PSMC4,PSMA3,PSMB5 |
| 2.125e-03 | -6.15 | CETN2 (centrin 2) | protein interactions | 1069 | 124 | 50 | 19454 | 5460 |
CCT2,FAS,CCHCR1,MYC,CSK,CUL3,PRMT6,BTF3,DEPDC1B,EIF4A2,PDCD5,CDC7,MACROH2A1,RPA2,USP39,RNF146,GTF2H5,GTF2H4,CCNH,CDK7,PITHD1,STAU1,ZC3H15,FTL,BAP1,SQSTM1,POLB,H2AC4,HNRNPD,POU5F1,TSNAX,ERCC3,TCP1,CCT7,MACROD1,CCDC127,CETN3,DCAF12L2,H2BC1,PNMA2,AP2S1,RAD23B,RAF1,CCT5,PNMA5,NUP153,H2AX,NUP37,MNAT1,BCKDK |
| 2.125e-03 | -6.15 | RPL36A (ribosomal protein L36a) | protein interactions | 6173 | 124 | 50 | 19454 | 5460 |
PELO,METAP2,CCNF,TUBB,BTF3,FBXO7,MYC,UBE2H,RC3H2,LMNB1,RNF113A,HSPB2,HSPA8,RPA3,BAP1,STAU1,SLC7A1,PAFAH1B1,ATG16L1,KLF4,HEXIM1,DCTN4,AIFM1,KLF9,ZBTB2,MDM2,MAP3K14,HDAC6,CSNK2A1,WWP2,SAV1,IFI16,MICB,SNRNP70,SRSF7,LTO1,MEPCE,VRK1,H3C1,MAP1LC3B,ANAPC13,MAP2K3,B3GNT2,FBP1,RPS11,NGB,CHMP4C,DNAJC2,EZH2,GINS4 |
| 2.125e-03 | -6.15 | CEBPA (CCAAT enhancer binding protein alpha) | protein interactions | 1050 | 124 | 50 | 19454 | 5460 |
PGAM1,CTNNB1,PSMD10,SMAD4,TGFB2,MRTO4,SMAD3,CEBPG,RB1,FUT1,SUMO3,AK5,CDK4,BATF,E2F4,NAA16,MAX,RAF1,VDR,MSX2,DDX39A,JUN,CAPN2,ATF3,SLC25A11,UBE3A,EWSR1,ZBTB16,HNRNPC,CDKN3,ATF4,MYC,NFYA,CREBBP,AR,RUNX1,TRIB1,COP1,VPS72,CEBPE,NR1I2,SPTBN1,CDKN1A,EDF1,XRCC5,FOS,DDIT3,EP300,TRA2B,PIAS1 |
| 2.132e-03 | -6.15 | Longin_dom | interpro domains | IPR010908 | 5 | 5 | 18521 | 5414 |
YKT6,SEC22C,VAMP7,SEC22A,SEC22B |
| 2.132e-03 | -6.15 | HIT-like | interpro domains | IPR011146 | 5 | 5 | 18521 | 5414 |
HINT1,FHIT,APTX,HINT3,HINT2 |
| 2.132e-03 | -6.15 | PFD_beta-like | interpro domains | IPR002777 | 5 | 5 | 18521 | 5414 |
PFDN2,PFDN6,PFDN1,PFDN4,PDRG1 |
| 2.132e-03 | -6.15 | AhpC/TSA | interpro domains | IPR000866 | 5 | 5 | 18521 | 5414 |
PRDX1,PRDX6,PRDX4,PRDX3,PRDX2 |
| 2.132e-03 | -6.15 | Peroxiredoxin_C | interpro domains | IPR019479 | 5 | 5 | 18521 | 5414 |
PRDX2,PRDX3,PRDX4,PRDX1,PRDX6 |
| 2.132e-03 | -6.15 | RNA_MeTrfase_FtsJ_dom | interpro domains | IPR002877 | 5 | 5 | 18521 | 5414 |
FTSJ1,CMTR2,MRM2,CMTR1,FTSJ3 |
| 2.133e-03 | -6.15 | NUP210 (nucleoporin 210) | protein interactions | 23225 | 169 | 65 | 19454 | 5460 |
CDC42,CFTR,ST7,ATG16L1,MET,RPA2,CDK1,METTL14,AKAP1,MTDH,DERL1,DNAJC3,RPA3,SIRT7,TMEM106B,G3BP2,HSPA5,EMC1,ADRB2,RHOBTB3,NONO,CUL3,NTRK3,NAPA,MAPRE1,CALU,DNAJC10,CDC7,UBE2I,SEC61B,CCNF,LMBR1L,RAN,ESR2,VIRMA,CTSB,DNAJC25,NUP153,LGR4,TBK1,E2F4,RANBP1,CAMK1,HSPA13,EZH2,TFRC,RPN1,CHMP4C,DISC1,EWSR1,IGF1R,NUP107,G3BP1,ETFA,DNAJC30,XPO1,DPP4,EED,COQ8A,COX4I1,PHB1,NUP35,OS9,DNAJB9,HNRNPL |
| 2.133e-03 | -6.15 | BCKDHA (branched chain keto acid dehydrogenase E1 subunit alpha) | protein interactions | 593 | 169 | 65 | 19454 | 5460 |
PDHA1,NDUFS3,CDK8,CYB5B,FAM136A,MTCH2,HOXB1,EEF2,POLL,EMC8,ZSCAN5A,IMMP2L,BCKDK,SLC25A10,HSPD1,EMC2,HSD17B8,HINT2,POR,POLB,PPM1K,NDUFB8,EMC4,COX5A,MTRF1,HDAC6,NDUFV2,UQCRH,NDUFS8,COX4I1,COQ10B,PHB1,FAHD1,GATD3,CORO1C,ACAA2,ARMCX3,COX6C,SPRYD4,CYC1,UQCRC1,DHRS4,PHB2,PDHB,NDUFS2,GRPEL1,AMACR,HADHA,TAFAZZIN,BOLA1,CUL3,AUH,HMOX2,TUFM,TOMM40,ATP5F1A,MRPL23,MGST3,ATP5F1B,NDUFAF4,CCDC90B,UQCRC2,CCNF,VDAC2,PTEN |
| 2.133e-03 | -6.15 | PIAS4 (protein inhibitor of activated STAT 4) | protein interactions | 51588 | 169 | 65 | 19454 | 5460 |
PIAS1,COIL,EIF5B,UBE2K,PTN,IRF7,CLK1,TMEM160,IRF3,PML,LMNA,RPA2,IL15RA,SNAI2,FTH1,SUMO1,GADD45G,LRIF1,APEX1,ZMYM2,TRIM27,UBE2I,TRIM24,OPTN,ZNF330,OAZ1,SMAD2,MAGEH1,RBBP8,TADA3,BRCA1,ZCCHC12,AR,MYC,CSK,TRIM32,TICAM1,CA10,MDC1,SATB1,SNIP1,TOP2B,RBPJ,SERPINA5,CBX3,NEFL,SMAD1,TOP3B,TP53,MALSU1,MDM2,RAB11B,HNRNPL,SUMO3,TOP1,SUMO2,ZHX1,MAP1LC3A,H2AZ1,SMAD3,AREL1,BRD3,SMAD4,NR4A2,LAMP2 |
| 2.135e-03 | -6.15 | LSM5 (LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 23658 | 72 | 32 | 19454 | 5460 |
SNRNP27,DDIT4L,RBFOX2,SNRPN,SART3,SNRPE,LSM2,UBE3A,S100B,PRPF4,MEPCE,LSM8,RIGI,DHX16,LSM4,KRAS,SPMIP10,PRPF31,RMI2,BAG3,SNRPB,LSM3,HNRNPD,RIT1,DDX23,LSM6,SNRPD2,GTF2B,PPP1R10,RBM42,ZNF511,SNRPD3 |
| 2.135e-03 | -6.15 | FBXO43 (F-box protein 43) | protein interactions | 286151 | 72 | 32 | 19454 | 5460 |
ALB,ANAPC2,RPS3,DLST,CDC20,TMPO,SLC25A12,CCT7,TCP1,ADRM1,TUFM,PRDX1,CDC23,CCT2,HSPA8,PCNA,CCT8,RPS27A,PSMC1,HSPA5,SKP1,CYFIP2,HNRNPF,EEF1G,ACTN4,PPP2R1A,CCT5,ARCN1,CDK1,LMNA,TFRC,RPN1 |
| 2.135e-03 | -6.15 | DPYSL3 (dihydropyrimidinase like 3) | protein interactions | 1809 | 72 | 32 | 19454 | 5460 |
YWHAH,YWHAG,ST13,MYC,CUL3,WWP2,CUL2,CBL,HAX1,OSGEP,CRMP1,MED4,UBE2H,RRP7A,BICD2,SEC23A,CCNF,TNIK,ARMC1,OTUD6A,UGT1A1,DYRK1A,TUBB,DDX39A,TUBA1A,EZH2,JUP,DISC1,BAP1,GALNT2,G3BP1,GPM6A |
| 2.135e-03 | -6.15 | SLC7A14 (solute carrier family 7 member 14) | protein interactions | 57709 | 72 | 32 | 19454 | 5460 |
GPR89A,RMDN3,B4GALT1,ELOVL4,TLCD4,AIG1,TECR,CD47,SPPL3,FAM20B,FATE1,TMED4,ADGRE2,TMEM179B,FCER1G,DOLK,DERL1,TMEM87A,PLPP6,FKRP,NSG1,CYB5R1,YIPF3,UBIAD1,CCDC167,YIPF4,FAM162A,AGTRAP,BET1,TMEM31,SMCO4,VAMP2 |
| 2.135e-03 | -6.15 | TREX1 (three prime repair exonuclease 1) | protein interactions | 11277 | 50 | 24 | 19454 | 5460 |
CHCHD2,SLC7A14,FNDC9,TMEM45B,CRB3,RNASEK,JAGN1,TMX2,ELOVL4,ACTA2,PRND,RPN1,TM4SF18,CYB561,ITGB8,MFSD14B,CLDN22,MOV10,RELL1,CCNB1,FAM174A,CD81,RAB23,TMEM205 |
| 2.135e-03 | -6.15 | DUOXA2 (dual oxidase maturation factor 2) | protein interactions | 405753 | 50 | 24 | 19454 | 5460 |
CBFB,ADGRG1,MAGED2,ODR4,DNAJB9,ASIC1,SLC25A4,MZT2B,TMEM106C,TMEM30A,PEX3,DNAJC19,TMEM87A,TMED1,GPM6A,PSEN1,TMEM209,COQ8B,MTX2,TIMMDC1,GLRB,SAMM50,TMX4,TM9SF1 |
| 2.135e-03 | -6.15 | IRF5 (interferon regulatory factor 5) | protein interactions | 3663 | 50 | 24 | 19454 | 5460 |
COPS4,PELI1,TRIM21,EP300,MAVS,MYD88,PPM1G,IRF3,GTPBP1,PSMB7,TOP3B,TBK1,TRIM15,SGTA,COPS2,SIN3A,IRF6,GTPBP2,TRAF6,PPIB,COPS5,XPO1,COPS7A,CREBBP |
| 2.135e-03 | -6.15 | TMEM208 (transmembrane protein 208) | protein interactions | 29100 | 50 | 24 | 19454 | 5460 |
RTN4,RETREG3,RABAC1,SCAMP2,CD63,TMX2,CXCR4,WDR83OS,SLC7A8,REEP4,BACH1,ATP5F1B,FAM241A,SPG21,SCN3B,RABL3,CSNK1E,REEP6,MFSD14B,STOM,SIGMAR1,FAM241B,LMNA,TMEM31 |
| 2.135e-03 | -6.15 | NR5A1 (nuclear receptor subfamily 5 group A member 1) | protein interactions | 2516 | 50 | 24 | 19454 | 5460 |
NFYA,CREBBP,AR,CTNNB1,RFC5,PROX1,NTAQ1,NR0B1,SP1,EIF4A3,ALYREF,GTF2B,THOC2,UBE2I,CKS1B,SOX9,EDF1,SOX2,JUN,DDX39B,SMARCD3,KRAS,CXXC1,PIAS1 |
| 2.136e-03 | -6.15 | regulation of proteolysis involved in protein catabolic process | biological process | GO:1903050 | 229 | 88 | 18204 | 5365 |
SOCS4,TRAF7,SUMO2,BAG2,USP38,RCHY1,ZER1,CSNK1E,NUPR1,UBB,CAMLG,FHIT,FZR1,CDC20,MDM2,UBE3A,CTSC,EPHA4,UBE2K,AQP11,DESI1,UFL1,RPL23,PSEN1,SGTA,MTM1,DNAJB2,PSME2,CSNK1A1,CCDC22,COP1,SOCS5,SMURF1,OPHN1,GABARAPL2,HECTD1,SUFU,HSP90AB1,FBXO22,USP5,CAV3,NFE2L2,CAV1,DET1,PRMT6,RNF139,WNT10B,TGFB1I1,RPS7,FBXW7,GABARAP,CCAR2,STUB1,GCLC,CLU,PITHD1,PSMC1,USP13,AKT1,NOP53,HFE,TAF9,GPX1,PSMC4,LAMP3,SVIP,DDRGK1,XPO1,ZFAND2A,PSMC3,ATP5IF1,PIAS1,PSMD14,TRIB1,RGN,CSNK2A1,RAD23B,PSME1,TMEM168,GSK3A,CDK5RAP3,SUMO1,PTEN,PSMC5,USP14,DISC1,PSMD10,PML |
| 2.137e-03 | -6.15 | EIF4ENIF1 (eukaryotic translation initiation factor 4E nuclear import factor 1) | protein interactions | 56478 | 293 | 105 | 19454 | 5460 |
RPS7,TUBA1A,TOP3B,BAG2,SRSF8,ZC3H7A,EWSR1,LSM14A,RPL31,HNRNPF,PCGF3,G3BP1,EIF3D,CPEB1,XPO1,SAV1,CNOT2,DDX1,KRT8,FUBP3,NUP35,EGLN3,TOMM22,LARP4B,CTBP1,NUP50,EXD2,ASB3,EEF1G,STAU1,YTHDF1,B9D2,FXR2,CREBBP,MYC,LSM14B,FIS1,FTSJ3,DCAF4,FBXW11,PHF21A,NFKBIA,EIF3K,PRRC2A,RPL19,SNRNP40,EIF4A2,ATP5F1B,RPL15,YTHDF2,CERK,LLPH,EFHC1,GARRE1,EIF3E,CNOT6L,KPNA2,EIF4EBP2,LSM4,CNOT7,EDC3,USP2,MOV10,SSX2IP,TRAK2,CDK6,EIF4E2,SMAD3,SYNCRIP,NOP9,RPS27L,RBMS2,AGO1,SNRPN,RBFOX2,WTAP,SCLT1,RPA2,LMNA,RPRD1B,RNF113A,SMG5,BCL6,EIF4E,TOMM20,OIP5,RBM22,KDM1A,MGAT5B,TIA1,RPL26,CEP85,CDC16,UBE2H,IGF2BP1,BICD2,TEX19,RC3H2,EIF3G,TRIM24,GSK3A,SMAP2,CTNNA1,RPGRIP1L,DAPK1 |
| 2.144e-03 | -6.14 | TEX10 (testis expressed 10) | protein interactions | 54881 | 166 | 64 | 19454 | 5460 |
DRG1,KPNA1,RPS2,H2AC4,SNRNP70,DDX23,PCED1A,DDRGK1,IFI16,CDC5L,ZBTB2,RBM42,SUMO2,FBXO32,SRP14,SRP72,HBP1,H2BC1,RPL15,SOX2,AURKAIP1,RAF1,ASF1A,CHCHD2,KRAS,RPS24,COX8A,RPL3,RPL31,RIT1,MAPRE1,MECP2,ZNF668,MYC,RPL10,APEX1,FBXO22,SNRNP40,CTSB,FGFBP1,TNFRSF1B,ZNF330,CCNF,LMBR1L,PELP1,MACROH2A2,RPLP0,GRM2,RPA2,H2AB1,CDC42,BET1,H1-5,MAPKAPK5,COIL,WDR55,FBXW7,RPL4,PHB2,UFL1,NPM3,PML,SIRT7,RPA3 |
| 2.144e-03 | -6.14 | Fatty acid biosynthesis, elongation, endoplasmic reticulum | KEGG pathways | M00415 | 13 | 10 | 7161 | 2463 |
ELOVL6,ELOVL7,ELOVL4,HACD3,ELOVL1,TECR,HACD4,HACD1,HACD2,ELOVL3 |
| 2.144e-03 | -6.14 | Fatty acid biosynthesis, elongation, endoplasmic reticulum | KEGG pathways | hsa_M00415 | 13 | 10 | 7161 | 2463 |
HACD1,HACD2,ELOVL3,ELOVL6,ELOVL7,ELOVL4,HACD3,ELOVL1,TECR,HACD4 |
| 2.155e-03 | -6.14 | DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12) | protein interactions | 54788 | 163 | 63 | 19454 | 5460 |
E2F4,CCDC47,RPN1,MAP1B,BAG2,PDIA6,IGF1R,RIGI,PSEN1,ADIPOR2,EDEM1,CALR,PDIA3,PPIB,CRBN,DNAJC7,STT3A,GATD3,DSTN,MARCHF4,FZR1,HNRNPL,LMAN1,EGLN3,CDK9,TPT1,CFTR,HSP90B1,LMNA,RPA2,TMEM106B,MME,DNAJC3,TTC1,DERL1,HSPA8,RER1,EMC1,RNF5,RNF41,TUSC2,HSPA5,GRPEL1,CUL3,OST4,MYC,ST13,BTF3,FBXO7,BRCA1,SPOP,DNAJB6,CALU,NTRK3,SELENOT,CCNF,STUB1,LMBR1L,SEC61B,SGTA,GANAB,ESR2,ABHD12 |
| 2.155e-03 | -6.14 | DHX38 (DEAH-box helicase 38) | protein interactions | 9785 | 163 | 63 | 19454 | 5460 |
SSRP1,RIGI,TSSC4,H3C1,CDC40,DHX16,KRAS,RING1,LDLRAD4,RUSF1,PPP4C,TMEM14B,CBX3,DISC1,LBH,CD2BP2,SUPT5H,CDC5L,DBR1,SNRPD3,BRD3,DDX23,YWHAH,CSNK2A1,WDR11,MOV10,IFI16,COIL,HSPA5,CERS6,PSENEN,PITHD1,STAU1,HSPA8,EP300,NUP50,PSMA3,DDX5,DDX39B,SLU7,RPA3,SIRT7,PML,MFAP1,ACACA,RPA2,LMNA,USP39,LSM2,CDK7,VIRMA,ESR2,SNRNP40,RPS20,CCNF,FAM177A1,EZH1,RIT1,BRCA1,ANAPC15,MYC,SMARCA5,CUL3 |
| 2.158e-03 | -6.14 | vacuolar localization | biological process | GO:1990849 | 61 | 29 | 18204 | 5365 |
SNAPIN,BORCS7,CPLX2,MRGPRX2,CHGA,FLCN,TMEM106B,HPS6,PTGDS,BORCS6,BLOC1S2,BORCS8,BORCS5,FAM98A,PIP4P1,HDAC6,TFEB,RNF167,PIK3CG,LAT2,RAB3A,KLC2,SYK,LAMTOR1,SNAP23,VPS33A,KXD1,KIT,CBL |
| 2.158e-03 | -6.14 | lysosome localization | biological process | GO:0032418 | 61 | 29 | 18204 | 5365 |
LAMTOR1,SYK,SNAP23,VPS33A,KXD1,KIT,CBL,PIP4P1,FAM98A,BORCS5,HDAC6,RNF167,TFEB,PIK3CG,LAT2,RAB3A,KLC2,HPS6,PTGDS,BLOC1S2,BORCS6,BORCS8,SNAPIN,CPLX2,MRGPRX2,BORCS7,FLCN,CHGA,TMEM106B |
| 2.160e-03 | -6.14 | thyroid-adenoma-nodule-goitre | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre | 57 | 27 | 16828 | 4835 |
EZH2,SMARCB1,PIK3CA,IDH2,PTPN11,AKT1,TSHR,GNA11,RB1,CTNNB1,STK11,GNAQ,HRAS,TPM3,PTEN,TERT,FGFR1,FBXW7,JAK2,TFG,TP53,MET,KIT,SMAD4,GOLGA5,IDH1,KRAS |
| 2.166e-03 | -6.13 | MAGEA3 (MAGE family member A3) | protein interactions | 4102 | 133 | 53 | 19454 | 5460 |
RAP1A,YTHDF2,EEF1A1,POLDIP3,PSMD12,CCT8,HSPD1,BCL7B,DHX9,RUVBL2,CASP12,PPM1B,DCAF5,PPP3CA,STAMBPL1,CLPX,PSMD3,PRDX1,IQSEC1,PPFIBP1,CCAR2,CPNE1,HSP90AB1,PSMB5,AIFM1,LSM2,CNTN1,TDRP,GTF2I,PACSIN3,PSMC1,MBD3,POLA2,DDX5,HNRNPH2,RPS5,GRB10,SMARCA5,RALB,PSMD1,EXOC5,ATP5F1A,ACTB,TUBB,STAT1,SRC,NDUFAF4,UBA3,UBB,FBLN5,CINP,PHKB,ALB |
| 2.166e-03 | -6.13 | MALAT1 (metastasis associated lung adenocarcinoma transcript 1) | protein interactions | 378938 | 133 | 53 | 19454 | 5460 |
RCL1,HNRNPAB,SFN,HNRNPC,ATP5F1A,CPSF2,PCCB,MATR3,PRDX2,TXN,CPSF1,LIG3,PSMC5,SF3A1,PSMC4,TRA2B,HNRNPA0,STAU1,FBXW7,HMGB1,SF3B1,SQSTM1,H2BC12,DDX23,AHSA1,PRDX1,CLPX,MRPS35,GLO1,GAPDH,NOP58,CCAR2,DKC1,DBT,G6PD,MRPS9,FUBP3,POLR2C,CAPN2,ILF2,PSMC3,STRBP,MTCH2,HADH,CD2BP2,HNRNPF,FARSA,ETFA,NOC4L,NSDHL,HNRNPA2B1,DHX9,SRSF7 |
| 2.172e-03 | -6.13 | ZMYM4 (zinc finger MYM-type containing 4) | protein interactions | 9202 | 157 | 61 | 19454 | 5460 |
HMGA1,MOV10,HNRNPD,LHX2,HSPB1,H2AZ1,EEF1AKMT3,ILVBL,HNRNPL,C1QTNF1,SUMO2,EGR2,ZMYM3,ELF1,SUPT5H,TP53,ZRANB2,SNRPE,TUBB4B,CHAMP1,CBX3,CDK8,EZH2,HAPSTR1,FHL3,CIPC,IMMP2L,PAX6,ZSCAN5A,H3C1,RUNX1,ZNF668,AR,GMNN,HNF1B,CUL3,HTRA2,H1-1,CCT2,ZMYM2,CSNK2B,ZNF174,APEX1,SRPK2,ESR2,MAD2L2,VIRMA,MATR3,TUBB,DYNLL1,PCK2,E2F6,KLF3,RPA2,ADNP,AKAP1,RPA3,NLE1,PML,KDM1A,NUCKS1 |
| 2.172e-03 | -6.13 | CDC14B (cell division cycle 14B) | protein interactions | 8555 | 157 | 61 | 19454 | 5460 |
MLH3,NUCKS1,NOP53,HMGB1,GINS3,MRPS7,AATF,HELLS,CCDC86,MTDH,MRPS34,MFAP1,TRIM36,CCND1,ZNF362,MRPS21,DEK,ZNF174,MRPS28,RPS12,GTF2F1,MRPL13,MRPS16,CIRBP,DCAF16,MRPS25,FTSJ3,XPOT,STK11,NOP16,SUB1,RPL26,MRPL16,HMGCS1,MRPS33,NOC4L,MSH6,PPP1R12A,THNSL1,MRPS11,GINS4,NUDT16,SRFBP1,TOP3B,MRPL47,TP53,HNRNPL,FZR1,MRPS23,SRP14,PSMB1,BCL10,SMAD4,SNRNP70,MRPS26,ANKRD50,BRD3,DDX50,HMGA1,CSNK2A1,GTF2E1 |
| 2.177e-03 | -6.13 | FtsJ | pfam domains | PF01728 | 5 | 5 | 17795 | 5224 |
MRM2,FTSJ3,CMTR2,CMTR1,FTSJ1 |
| 2.177e-03 | -6.13 | Longin | pfam domains | PF13774 | 5 | 5 | 17795 | 5224 |
VAMP7,SEC22A,SEC22B,YKT6,SEC22C |
| 2.177e-03 | -6.13 | 1-cysPrx_C | pfam domains | PF10417 | 5 | 5 | 17795 | 5224 |
PRDX2,PRDX3,PRDX6,PRDX4,PRDX1 |
| 2.177e-03 | -6.13 | AhpC-TSA | pfam domains | PF00578 | 5 | 5 | 17795 | 5224 |
PRDX3,PRDX2,PRDX1,PRDX4,PRDX6 |
| 2.177e-03 | -6.13 | Prefoldin_2 | pfam domains | PF01920 | 5 | 5 | 17795 | 5224 |
PFDN6,PFDN2,PFDN1,PFDN4,PDRG1 |
| 2.178e-03 | -6.13 | NMT1 (N-myristoyltransferase 1) | protein interactions | 4836 | 154 | 60 | 19454 | 5460 |
EIF2B3,RPA2,CTBP1,SCLT1,CAPN1,ACBD6,STAU1,FBXW7,RP2,MARS1,TUSC2,RPA3,BAP1,RFC4,HSPA8,BICD2,TBCE,MLF1,USP14,HPCA,RFTN2,MGST3,IRF2BP1,VIRMA,RPL19,SRC,UBTD1,CCNF,PSPC1,RTRAF,ZNRF1,GNAZ,CAPN2,ILF2,TP53,RAF1,MARCKSL1,TOP3B,KRAS,RIGI,ABCF1,RPL31,RTCB,DHX9,SEPTIN7,RPL23A,LRATD1,AGR2,NAB2,DDX1,DDRGK1,CSNK2A1,EIF2B2,RPS16,CEP19,TRMT61A,DEFB1,ACSL4,CD274,CDCA3 |
| 2.179e-03 | -6.13 | regulation of cellular response to transforming growth factor beta stimulus | biological process | GO:1903844 | 182 | 72 | 18204 | 5365 |
CHST11,MIR497,MIR21,MIR30B,MIRLET7B,PPARG,IL4,MIR373,MIR106A,MIR342,SMAD2,BRMS1,NREP,HTRA1,HSPA5,SMURF1,MIR17,MIR20A,LDLRAD4,DKK3,CAV3,ING2,CITED1,MIR424,MIRLET7G,HSP90AB1,SAP30L,EID2,LEMD3,CAV2,BCL9,MIR204,TGFB1I1,FKBP1A,SIN3A,FOLR1,SMAD4,CREBBP,MIR361,STK11,PPARA,MIR140,USP15,MIR98,SPRY1,TGFB3,FAM89B,PBLD,STUB1,ING1,MIR142,MIR9-1,MIR490,SPRED2,MIR145,FLCN,MIR302B,ZNF451,RBBP4,TP53,DLX1,SMAD3,BRMS1L,MIR101-1,SPRED1,PEG10,RBBP7,IL17F,EP300,TWSG1,SDCBP,SAP30 |
| 2.180e-03 | -6.13 | LARP1B (La ribonucleoprotein 1B) | protein interactions | 55132 | 139 | 55 | 19454 | 5460 |
RABIF,RPL19,ACTB,GSK3A,RPS20,RPS3,TBC1D25,ELAVL2,H1-1,DCAF4,RPL26,CUL3,HNRNPC,DGCR8,STAU1,NOG,EXD2,RPLP0,LARP4B,METTL14,RBMS2,H1-5,PABPC5,FGF17,SURF6,PAIP1,RPS10,FZR1,PRR3,SYNCRIP,SRSF1,RPS2,SNRNP70,YWHAH,HNRNPA1,YWHAG,DDRGK1,TRA2A,MOV10,MEPCE,SRSF4,RPL17,NUP42,SRSF7,RPL31,PABPC1,LSM14A,ILF2,H1-3,H2AX,APOBEC3D,KIF2A,PAIP2B,RAF1,RPSA |
| 2.180e-03 | -6.13 | MAD1L1 (mitotic arrest deficient 1 like 1) | protein interactions | 8379 | 139 | 55 | 19454 | 5460 |
BIRC2,HSPA8,PML,VPS28,COIL,LMO3,NEK2,SUMO1,PACRG,MFAP1,LMNA,CCNF,TRAF1,ESR2,APEX1,MAD2L1,CDC20,BMP1,TRIM29,USP16,NONO,NTAQ1,PRKACB,CCNB1,CCHCR1,COP1,STK24,RUSF1,RIGI,VRK1,PSMA1,NUDCD3,SUPT5H,TOP3B,MAX,RNF8,MAD2L1BP,CBX3,SEC23A,FBXO32,SIN3A,CDC5L,FAM118B,SUMO2,TSC22D3,PPP1R18,HNRNPL,GAS8,SPATA2,TPM3,YWHAH,YWHAG,NDC80,USP15,ASB7 |
| 2.182e-03 | -6.13 | SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) | protein interactions | 23384 | 151 | 59 | 19454 | 5460 |
PPP1R12A,FBXO25,MDC1,RNF26,ERLEC1,G3BP1,KCTD17,SOX2,ACTN4,ISG15,RPL15,RAF1,FBP1,NUPR1,CSTPP1,CHMP4C,CAPZA2,DISC1,CACNB3,RPL8,FEZ1,G2E3,SURF6,YWHAH,HDAC6,YWHAG,CTNNB1,CSTA,TWNK,ARPC2,DDX39B,HSPA5,FBXW7,STAU1,PPP1CB,CFTR,DUSP22,ATG16L1,RPS14,LPXN,TRIM36,QRSL1,AP2M1,UBE2I,NFKBIA,CTTN,VIRMA,ESR2,PTPRZ1,BTF3,USP14,PPP1CC,MYC,ZNF250,PDE7A,VMP1,MAPRE1,IRAK1BP1,STN1 |
| 2.182e-03 | -6.13 | DNAAF5 (dynein axonemal assembly factor 5) | protein interactions | 54919 | 151 | 59 | 19454 | 5460 |
DDRGK1,P2RY10,HSPB8,MOV10,UBXN6,GSTM3,NCR3LG1,ARL4D,ARMC1,FEZ1,EEF1AKMT3,HRAS,PTP4A3,TRIM35,HNRNPL,DCUN1D1,GFPT1,PPP2R1A,COMTD1,PLD3,CYB5B,RAD23B,POLR2C,AQP3,EZH2,EFNB1,RUSF1,SEMA4C,CD80,HNRNPF,ZBTB16,CASP4,CUL3,GSTK1,CIAO1,GPR17,OPRM1,ILK,UBE2H,DPEP1,CHRM4,CCNF,LMBR1L,APLNR,HCST,RFXANK,NPY2R,PGRMC1,FAM234A,FKBP10,STOM,RPA2,LMNA,USP39,CD40,RPA3,CXCR4,SLC15A1,NPTN |
| 2.183e-03 | -6.13 | organic acid metabolic process | biological process | GO:0006082 | 817 | 278 | 18204 | 5365 |
GAMT,TST,PLAA,ATP1A2,CYP1A1,P4HA2,CYP2C8,EHHADH,AZIN1,GPX4,XBP1,RGN,TECR,MTARC2,AKR1A1,EGLN2,SCPEP1,ACACA,IDH1,RIMKLA,LDHAL6B,KGD4,ILVBL,GAD2,PLA2G5,ACO1,HACD4,PDHB,PCCB,ADTRP,SULT1A3,FKRP,PFKFB2,GCLC,LDHA,SLC5A6,PGAM1,ABHD14B,SEPHS1,AMACR,FMO1,GSTM2,PYCR2,PEX13,PLA2G15,SLC2A3,CYP2R1,CRTAP,GSTP1,LIAS,CPT2,GPT,ACADS,GPX1,CPT1B,IGF1,DPEP1,UCP2,CRYL1,HSD17B10,OSBP,ASPA,RIMKLB,EPHX1,MDH1,SLC6A8,CYP4F22,ETFA,HADH,PCK2,CYP2D6,MGST2,OGDHL,HACD3,BRCA1,ABHD12,MTAP,ASRGL1,LDHB,ODC1,NUDT19,CMAS,PNPLA8,CD36,SLC25A17,IDH3B,ST3GAL1,PRKAG1,ACOT6,IREB2,GFPT1,ADSS2,PC,SLC25A42,ELOVL7,CRAT,PHYH,GNMT,UST,ACADSB,SULT1B1,GLYAT,PPARA,CYP2F1,SLC1A3,CYP26A1,MIF,MORC2,HTR2A,ENO1,DLAT,OAT,ERRFI1,MBLAC2,VDAC1,NANP,HEXA,IER3,ABHD6,ALDH1L1,ABHD10,ACAA2,PLA2G4B,SEPHS2,PTGES,ADIPOR2,DEGS1,AUH,TPH2,FMO2,CYP4F8,CYP27A1,ACSL4,MMUT,HACD2,IDH3A,SUCLG2,ALDH1A3,AMT,BPGM,ACAT1,MECR,STAT5A,ACOT8,GSTM4,FMO3,MTHFS,TPST1,PDHA1,AZIN2,TLR2,NDP,CYP1B1,ARG2,RDH10,ECHDC1,PLP1,GGT7,ANKH,LIPT2,ELOVL1,ALOX5AP,MGAT4A,FOLR1,CBR4,MPST,SLC25A44,ELOVL6,CYP2C9,HPGDS,AKR1B1,ABHD5,PYCARD,ADIPOR1,SYK,DDAH1,PPAT,CYP4F12,CYP3A5,MSMO1,BCKDK,SDS,GPAM,GLUL,PRKAB1,SLC23A2,FA2H,EGLN3,PCBD1,MCAT,ADIPOQ,SLC2A1,SHMT1,CYP7A1,ELOVL4,PGK1,LIPA,ACOX1,SLC16A1,ASNSD1,PPARG,DDAH2,PAPSS2,NUDT7,CRYM,GNPDA1,GSTO2,CDO1,ADH1A,SESN2,SLC25A32,GSTA1,FAH,SLC25A12,GSTO1,SLC38A1,PYCR1,CYP2C18,AASDHPPT,PPM1K,MGST3,HEXB,LYPLA1,ABHD2,AKR1C2,PTGDS,HNMT,GNPDA2,AKR1C1,GAPDH,CYP4V2,ETFB,HACD1,MECP2,AIG1,ACO2,ADH1B,ENO2,FAHD1,ATF4,UGDH,SORD,UGT2A3,HSD17B8,IDH2,LEP,MTHFD2L,PTGES3,FGFR1,SLC25A21,UGT1A1,CRABP2,NDUFAB1,COMT,SCD5,ACSS2,GHR,GGTA1,CYGB,ACBD7,PGM1,PEDS1,LYPLA2,DECR2,DLST,CSGALNACT1,CYP39A1,DBT,GNPAT,ELOVL3,ACCS,FADS2,SERINC3,IDO1,GMPS,ST6GAL1,HADHA,TP53 |
| 2.184e-03 | -6.13 | cellular response to growth factor stimulus | biological process | GO:0071363 | 494 | 175 | 18204 | 5365 |
YES1,COL1A2,WNT2,RAP1A,CX3CR1,EIF4A3,MSX1,TMEM108,SMAD3,RAF1,MIR1298,DUSP22,IL10,XCL1,FGF3,TWSG1,FGF17,MIR23A,CHRDL1,NOG,ITGB8,ACVR1B,HFE,RAB14,FGF7,FGF16,CITED1,EID2,SOSTDC1,NDN,PML,PDE2A,BMPR1B,CCL2,FOS,FEZ1,ARF6,RAB35,FUT8,FRS3,MIR183,ACVR1,NDP,CD2AP,DDX5,EHD1,PDCD4,STK16,SOST,NTF4,FKBP8,TP53,PIK3CA,TAC1,CXCL8,MDM2,TLR4,KLF4,PAX9,PTPN11,SRC,FGF22,FGFR1,EXT1,LPXN,BMPR2,VEGFA,FGF23,EGR1,BMPR1A,SMAD9,SHOC2,CCNA2,MIR30A,STMN2,FLRT2,NTRK3,CXCL13,MIR212,PPARG,NTRK2,GAB1,ACAP2,FGF10,CTNNB1,CTSK,HYAL2,MAP1B,MAP2K3,DUSP3,TGFB2,NOTCH2,ACTA2,SMAD4,DDIT4,AKT1,TGFB3,NDNF,SPINT2,ELAVL4,GCLC,COL3A1,PDE8A,WNT7A,VSTM2A,ITGB5,RGMA,SHC1,MIR339,FGF1,CAV2,GAD2,NRP1,SMAD1,RGMB,CRKL,CHST11,SNAI2,BECN1,TGFBR2,FMOD,MIR130A,PAK2,FLRT3,CBL,SOX9,MIR20A,GRIA1,BGLAP,MIR142,MARS1,HSPB1,CSNK1E,FERMT2,FLCN,SFRP1,IGF1R,CREB1,NDST1,UBE3A,DLX1,ACVR1C,TMEM100,CCL5,VEGFC,SMAD5,EEF1A1,USP15,INPP5K,ID1,PDCD5,JUN,NUS1,MEF2C,MSTN,ARPC3,ZYX,TAB1,DSTYK,USP8,FURIN,CAV1,PAX6,FGFBP1,MIR21,MIR30B,DTYMK,MIR149,CLDN1,EHD4,MSX2,SMAD2,TNFRSF1B,HTRA2,SMURF1 |
| 2.185e-03 | -6.13 | ZNF48 (zinc finger protein 48) | protein interactions | 197407 | 148 | 58 | 19454 | 5460 |
RPL13A,RPL7L1,ESR2,RPL22,APEX1,RPS3,ZNF22,RPS9,FGFBP1,SF3B4,RPL37A,PRKRA,FTSJ3,FYTTD1,GTPBP2,H1-1,NSA2,RPL7A,RPF2,MYC,PRPF31,RPL4,STAU1,BRIX1,RPL27,EP300,APOBEC3C,ZNF770,RPL26L1,RPLP0,NOTCH2,RPL27A,RPS10,SURF6,DKC1,RPL32,SRSF1,RPL8,HP1BP3,RPLP2,MPHOSPH10,SNRNP70,RPL10A,FNDC11,RPL17,EIF3E,SRSF4,RPL3,FBXO11,RPL23A,RBM34,GLE1,SART3,RPL18,TOP3B,RPL15,MAK16,TAF1D |
| 2.185e-03 | -6.13 | human chr7q31.2 | chromosome location | human chr7q31.2 | 18 | 10 | 26134 | 5823 |
MIR6132,CAV1,MET,ASZ1,ST7,TES,CFTR,WNT2,CAV2,CAPZA2 |
| 2.187e-03 | -6.13 | SFXN4 (sideroflexin 4) | protein interactions | 119559 | 92 | 39 | 19454 | 5460 |
LCN1,NMRAL1,ABCE1,NDUFA4,PML,SFXN1,RPA3,MAIP1,TF,UFL1,HSCB,TTR,TNFSF8,SERPINA3,APOO,TUBA1A,FURIN,SERPINA1,JCHAIN,PTPN22,RPA2,BPIFB1,CCNF,AIFM1,LMBR1L,SLC25A12,APLNR,EGLN3,RAMP3,DDRGK1,HP,MTMR12,CUL3,BABAM1,MOV10,DPP4,MAPK4,UBE2H,LACRT |
| 2.187e-03 | -6.13 | PQBP1 (polyglutamine binding protein 1) | protein interactions | 10084 | 92 | 39 | 19454 | 5460 |
MAPRE1,SUGP1,MYC,COPS7A,SNRPB,PPP1CC,SNRNP40,TOP1,LRIF1,MRPL53,RSRC1,MRPS28,EZH2,LSM2,PDHA1,SFTPC,TFIP11,MED31,TXNL4A,RAF1,SF3A1,WDR77,UBL4A,WBP11,EEF1A1,PPP1CB,LSM4,RCVRN,H3C1,SRPRB,RBM22,STAU1,SSRP1,SNRPA,RPS28,ZC3H11A,EWSR1,HNRNPH2,ERG28 |
| 2.187e-03 | -6.13 | EPN2 (epsin 2) | protein interactions | 22905 | 92 | 39 | 19454 | 5460 |
LAMTOR1,TRIM23,MYO6,YWHAZ,H1-10,RHOB,EPHA2,YWHAB,DPP4,ATG9A,CDIP1,YWHAG,YWHAH,MB21D2,KCTD10,STX6,DIRAS3,ESR2,HRAS,TUBA1B,SMAP2,GJA1,FGFR1,RNF8,WBP1L,UBA52,TRIM62,SMAD1,KRAS,LITAF,TRIM26,PIP4P1,RPS27A,STX7,RNF11,EIF3E,WBP2,FAM168A,ARRDC3 |
| 2.198e-03 | -6.12 | myoepithelial_carcinoma | COSMIC cancer mutations | myoepithelial_carcinoma | 17 | 11 | 16828 | 4835 |
FBXW7,TP53,CTNNB1,KIT,MET,PTEN,PIK3CA,KRAS,HRAS,SMAD4,STK11 |
| 2.198e-03 | -6.12 | anaplastic | COSMIC cancer mutations | anaplastic | 17 | 11 | 16828 | 4835 |
PIK3CA,PTEN,SMAD4,HRAS,CTNNB1,KRAS,IDH1,AKT1,NF2,CDKN2C,IDH2 |
| 2.198e-03 | -6.12 | salivary_gland-carcinoma-myoepithelial_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-myoepithelial_carcinoma | 17 | 11 | 16828 | 4835 |
KIT,MET,HRAS,CTNNB1,KRAS,TP53,FBXW7,STK11,PIK3CA,PTEN,SMAD4 |
| 2.207e-03 | -6.12 | NLE1 (notchless homolog 1) | protein interactions | 54475 | 209 | 78 | 19454 | 5460 |
RPA3,SIRT7,NLE1,CCDC86,DERL1,NPM3,STAU1,PHB2,BRIX1,RPS14,RPL27A,CCND1,FTH1,RPA2,APOBEC3C,METTL14,HNRNPH3,MACROH2A2,OPTN,CCNF,CPSF1,RPS3,CHRM5,PRKRA,RPS9,BUB3,RPL13A,ESR2,RPF2,MYC,RPL7A,CUL3,THAP7,KANSL3,PCCB,MECP2,CCT2,ATG3,RIT1,DNAJB6,NSA2,TOP2B,TCOF1,RPL3,EWSR1,KRAS,RPS4X,RPL28,SSRP1,RIGI,TRMT1L,TOP3B,GBE1,CCT5,MAP1LC3B,CD2BP2,RPL15,ZMYM4,LLPH,RBM34,RPS11,RPL18,RPL9,RPL35A,PRNP,LYAR,DKC1,NOP9,SURF6,LRWD1,CCT7,IFI16,PLEKHO1,GAPDH,MPHOSPH10,NOL12,CDK12,TOPBP1 |
| 2.212e-03 | -6.11 | PTBP2 (polypyrimidine tract binding protein 2) | protein interactions | 58155 | 61 | 28 | 19454 | 5460 |
HNRNPL,MATR3,PNP,SNRNP40,CDC5L,MACROD1,SRPK2,PHB1,GSK3A,EIF5A2,HNRNPD,MAGOH,CSK,HNRNPC,HNRNPAB,UBE2E2,HNRNPA1,G3BP1,TOM1,PRDX4,SNRPA,RPA3,EP300,RPA2,ATG16L1,SOX2,TRAF2,JUN |
| 2.212e-03 | -6.11 | CERS4 (ceramide synthase 4) | protein interactions | 79603 | 61 | 28 | 19454 | 5460 |
TMEM254,STX8,TEX264,JAGN1,TOMM6,CERS6,SMIM11,STX7,LPAR1,SLC7A1,TMEM176A,CTXN3,JUN,OTULINL,PLP2,NEU1,SLC35F6,RABL3,VAMP2,SEC61B,CYB5R3,TSPO2,FATE1,CLEC1A,FCER1G,SLC35A1,SCAMP5,FXYD6 |
| 2.212e-03 | -6.11 | OBSCN (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF) | protein interactions | 84033 | 61 | 28 | 19454 | 5460 |
ACOT13,VPS18,FGFR1,SH3GLB2,TOP3B,TUBA1A,HSPA5,UBE2A,MYH2,TCOF1,MTDH,FHL3,PCNA,POC1B,BRCA1,ATP1A3,HNRNPD,MOV10,IFI16,USP14,GAPDH,SLC1A3,MPG,FBXO22,HNRNPL,VIRMA,WDR82,GGT7 |
| 2.220e-03 | -6.11 | response to diacyl bacterial lipopeptide | biological process | GO:0071724 | 5 | 5 | 18204 | 5365 |
MIR105-1,CD14,TLR2,CD36,TLR6 |
| 2.220e-03 | -6.11 | regulation of polyamine transmembrane transport | biological process | GO:1902267 | 5 | 5 | 18204 | 5365 |
AZIN1,AZIN2,OAZ2,OAZ3,OAZ1 |
| 2.220e-03 | -6.11 | cellular response to diacyl bacterial lipopeptide | biological process | GO:0071726 | 5 | 5 | 18204 | 5365 |
TLR6,CD36,MIR105-1,TLR2,CD14 |
| 2.220e-03 | -6.11 | antigen processing and presentation, endogenous lipid antigen via MHC class Ib | biological process | GO:0048006 | 5 | 5 | 18204 | 5365 |
CD1C,CD1B,CD1A,CD1D,CD1E |
| 2.220e-03 | -6.11 | negative regulation of IRE1-mediated unfolded protein response | biological process | GO:1903895 | 5 | 5 | 18204 | 5365 |
BFAR,HSPA5,DNAJB9,DDRGK1,UFL1 |
| 2.220e-03 | -6.11 | negative regulation of interleukin-21 production | biological process | GO:0032705 | 5 | 5 | 18204 | 5365 |
MIR222,MIR221,MIR215,MIR192,MIR21 |
| 2.220e-03 | -6.11 | negative regulation of cell chemotaxis to fibroblast growth factor | biological process | GO:1904848 | 5 | 5 | 18204 | 5365 |
MIR149,CXCL13,MIR424,MIR15A,MIR16-1 |
| 2.229e-03 | -6.11 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | molecular function | GO:0016655 | 50 | 25 | 18094 | 5411 |
NDUFC2,NDUFS8,AKR1C1,NDUFA5,NDUFS2,AKR1C2,NDUFB4,NDUFB5,NDUFA4,NDUFB7,CRYZ,DHRS4,NDUFV2,NDUFB6,NDUFS3,NDUFA12,NDUFB10,NQO1,NDUFS6,NDUFA1,TP53I3,CBR3,NDUFB8,NDUFA2,CBR4 |
| 2.237e-03 | -6.10 | regulation of alpha-beta T cell activation | biological process | GO:0046634 | 116 | 49 | 18204 | 5365 |
CD86,IL2RG,IL12B,XCL1,IFNG,TWSG1,EP300,VSIR,AGER,KLHL25,BATF,BCL6,CD274,HFE,IL12A,FOXP3,LILRB1,SYK,JUNB,SASH3,NKAP,HMGB1,IL18,PNP,CD83,IL23A,ARG2,CD80,CBFB,CD28,RC3H2,IL2RA,TNFRSF14,JAK2,MIR21,CD81,LILRB4,CCL19,IRF4,TGFBR2,CCR2,IL2,ZBTB16,PRKCQ,IRF1,NLRP3,NDFIP1,RUNX1,SOCS5 |
| 2.238e-03 | -6.10 | CTBP1 (C-terminal binding protein 1) | protein interactions | 1487 | 360 | 126 | 19454 | 5460 |
MDC1,TOR2A,IGF1R,KLF10,RAB1A,EHD4,FURIN,NUPR1,TRAPPC13,BMPR2,H2AX,TP53,MDM2,CAND1,RB1,CD274,WDCP,GTF2B,FOXP1,TRAPPC2L,NME2,TUBG1,GAPDH,CSNK2A1,BCL6,RBM22,HDAC3,KDM1A,RTN4,SYVN1,KLF4,UBE2M,SNAI2,KLF12,FBXL19,CCND1,FUT8,SNRPN,VIRMA,DYRK1A,CDC20,KCNIP3,UBE2I,PTEN,B4GALT1,CSNK2B,ZBTB18,CTNNA1,CCNF,UBE2H,LCORL,SPOP,AR,NTAQ1,RUNX1,CIAO1,AKT1,RAB2A,FANCG,SAR1B,SATB1,SSNA1,PLCB1,EWSR1,SLC39A3,FBXO11,SART3,RND3,SOBP,EZH2,SAP30,JUN,SOX2,E2F4,B3GNT2,EGLN3,INA,HNRNPL,EED,FBXO32,SIN3A,HNRNPD,POU5F1,CDC23,DCAF11,CTNNB1,ACTL6B,NOL4,RAB5C,DYRK1B,PRPF19,FOXP2,MRPS7,SKP1,EP300,SLC35F2,HDAC5,ZBTB42,FKBP1A,KLF3,ADSS2,MED23,ABCB1,CTBP1,FUNDC1,NUP62,ESR2,RBBP4,B4GALT3,ANAPC2,ZMYM2,ELK3,ATXN1L,DOK4,SERPINH1,SP1,BRCA1,RBBP8,BAG3,SLC30A5,CUL3,IKZF2,TXNRD2,CDKN2D,MYC,CREBBP |
| 2.242e-03 | -6.10 | positive regulation of telomerase activity | biological process | GO:0051973 | 33 | 18 | 18204 | 5365 |
HSP90AB1,HSP90AA1,MYC,KLF4,TCP1,GREM1,NEK7,XRCC5,PARM1,PTGES3,NEK2,CCT2,DKC1,WRAP53,PRKCQ,MAPKAPK5,PKIB,TNKS |
| 2.245e-03 | -6.10 | METTL13 (methyltransferase 13, eEF1A N-terminus and K55) | protein interactions | 51603 | 75 | 33 | 19454 | 5460 |
THBS3,PIK3CG,SNRPA,RIGI,CDK20,STAU1,THAP1,TRAF2,MAP1LC3B,RAF1,DTWD2,LMNA,FOXS1,EEF1AKMT3,CCNF,SYNCRIP,NTMT1,APLNR,AGK,BUB3,DNAJC8,AR,DDRGK1,LAMP3,ANKMY2,CUL3,PTPN11,FAM174A,SIGLEC5,MYC,KLK5,FAS,ELMO2 |
| 2.246e-03 | -6.10 | MLH1 (mutL homolog 1) | protein interactions | 4292 | 237 | 87 | 19454 | 5460 |
SPTAN1,PTGDS,FBXO32,PPP2CB,NDUFB8,ELP6,SKIC8,AGR2,CDCA7L,VAMP8,ENKD1,PSMA1,ZBED1,TRMO,RUVBL1,PCNA,RUVBL2,PPP2R1A,EEF2,E2F4,APEX1,USP5,DES,PSMD6,TRIM29,FAM83B,MCM8,ELMO2,CKB,BRCA1,MYC,CUL3,PYGB,MLH3,EEF1G,RADX,ACER3,HSPA8,RFC4,NANP,FAM50B,CSNK1A1,ZER1,MYL6,PRR5L,CDK9,SHPRH,AIFM1,MAP2K6,LY96,TDRD7,HDAC6,MPG,API5,MSH6,FKBP8,KPNA2,TOLLIP,ZC3H11A,RAD23B,EXOC3,CAPZA2,H2AX,SMAD1,TXN,CTSB,SEC61A1,ZMAT5,VAMP3,CCNF,CTTN,TMSB4X,ZNF177,SPOP,TRIM23,ATP5F1A,SLC25A1,GABARAP,NME4,SQSTM1,RPA3,PML,NBN,GSTP1,LUC7L3,RPA2,STX17 |
| 2.246e-03 | -6.10 | DPH5 (diphthamide biosynthesis 5) | protein interactions | 51611 | 22 | 13 | 19454 | 5460 |
HNRNPL,KRAS,MYG1,ZYX,NUDT2,ENO1,BICD2,RIT1,MOV10,GCLC,CCS,CD2AP,UFD1 |
| 2.246e-03 | -6.10 | Stub1 (STIP1 homology and U-Box containing protein 1) | protein interactions | 56424 | 22 | 13 | 19454 | 5460 |
SOD1,CCNF,APOBEC3G,UBE2N,UBE2D3,SMURF1,CHIC2,BMPR1B,C9orf72,PLEKHO1,UBE2V1,UBE2D1,HSP90AA1 |
| 2.246e-03 | -6.10 | WNK4 (WNK lysine deficient protein kinase 4) | protein interactions | 65266 | 22 | 13 | 19454 | 5460 |
CLDN1,CLDN3,MAEA,BCL6,HMGB1,FBXO22,COPS5,CUL3,AKT1,CLDN4,KLHL3,OXSR1,HSP90AA1 |
| 2.246e-03 | -6.10 | TPRG1 (tumor protein p63 regulated 1) | protein interactions | 285386 | 22 | 13 | 19454 | 5460 |
STX17,CGRRF1,FCER1G,CCR1,MFSD14B,APOC2,SCN3B,CIDEB,REEP4,APOC4,TMX2,HSD17B11,RETREG3 |
| 2.246e-03 | -6.10 | Get4 (golgi to ER traffic protein 4) | protein interactions | 67604 | 22 | 13 | 19454 | 5460 |
BAG2,TRAFD1,MAGED2,ATP5MK,HSP90AB1,ATXN10,SRPRB,PSMD4,RNF5,UBL4A,MAT2A,RNF126,UBAC2 |
| 2.246e-03 | -6.10 | G_PROTEIN_GAMMA | prosite domains | PS50058 | 13 | 9 | 12186 | 3388 |
GNG13,GNG11,GNG7,GNG10,GNG12,GNG2,GNG3,GNGT2,GNG5 |
| 2.247e-03 | -6.10 | MYL6B (myosin light chain 6B) | protein interactions | 140465 | 95 | 40 | 19454 | 5460 |
SOX2,ISG15,CDC42,TP53,MYL12B,RAF1,WDR77,MYL6,HEXIM1,NGB,CAPZA2,TFCP2,FOS,ATF3,RIGI,HSPA5,UBE2A,MEPCE,FBXW7,TRIM37,HUWE1,TNF,HDAC6,BTF3,CUL3,MYC,BRD3,SP1,RHOB,MYO6,PHB1,FHIP1B,NCKAP1,MDM2,TMPO,MYL12A,RHOH,DYNC1I2,STAT1,OCRL |
| 2.247e-03 | -6.10 | PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1) | protein interactions | 9051 | 95 | 40 | 19454 | 5460 |
EHHADH,UBE2W,FASLG,TULP3,CD2AP,RPL29,BZW2,SDCBP,FDFT1,TFIP11,RINT1,RPL31,TTC1,RPL3,RPL23A,RUVBL1,WASL,LSM4,PYCARD,CARS1,EXOC5,RPL26,PRPF31,ZNF175,ZNF688,RPL32,SCNM1,TRAF3IP3,DNM2,RPL9,RPL37A,HAPLN2,TUBB,RPL35,ACTB,RPL35A,BUB3,CD2,HMG20A,CCDC172 |
| 2.247e-03 | -6.10 | H2BC13 (H2B clustered histone 13) | protein interactions | 8340 | 95 | 40 | 19454 | 5460 |
MYC,HMGA1,YWHAG,CD81,YWHAH,BTF3,HDAC6,PSMD14,AGR2,H2AC4,SPOP,TMEM196,ICAM1,HAX1,HNRNPD,ARMC1,AP2M1,USP16,CAND1,VIRMA,CDK9,TP53,CDK7,ELK4,CDC42,H2BC1,CTBP1,HEXIM1,SIRT7,MAP1B,PPM1G,PSMA3,SMG5,NUP50,PRKCB,HAPSTR1,GPM6A,NOP53,POLL,MEPCE |
| 2.252e-03 | -6.10 | hemopoiesis | biological process | GO:0030097 | 688 | 237 | 18204 | 5365 |
PTPN22,CEBPE,FAM20C,RABL3,CCR7,STAT6,IFNA13,CCR6,LBR,RPL22,UCP2,EP300,NOTCH2,CD164,CLPB,TGFB2,PIK3R3,HYAL2,CTSK,BAK1,RHAG,CTNNB1,TOX,IL2RG,JAGN1,TF,DHRS7B,SART3,KIT,IL2,TGFBR2,ATP5IF1,LTBR,SNAI2,HEATR9,PICALM,DNAJB9,JAK2,TIRAP,IRF8,HDAC5,SYVN1,TOB2,CDK5RAP3,FOSL2,CD34,SNRK,ROGDI,CD83,VPS33A,CD79B,SASH3,JUNB,LILRB1,FOXP3,AGPAT5,NFIL3,BVES,SMAD5,CSF2,STK3,TNFSF8,SLC48A1,ITM2A,FOXP1,ADD2,FCER1G,ARL11,IL12B,GLO1,RPS14,RSAD2,CREB1,SFRP1,FLCN,IL6,TRAF3IP2,BAX,GP9,PRDX3,IFNA10,MMP9,CDC42,RUNX1,TMEM91,IFNK,IL4,JAK1,MYD88,MAEA,TCTA,PSMB11,ZBTB16,PDP2,CD81,PSEN1,INHA,TMEM190,CD4,IFNA2,IFNB1,TYROBP,SIN3A,SOCS3,SSBP3,LYAR,RC3H2,WNT10B,CD28,PTPRZ1,BABAM1,CBFB,ACP6,WDR38,BAP1,IREB2,NCAPG2,MEF2C,ST3GAL1,HMGB1,TOP2B,SYK,CD1D,MPIG6B,EPHA2,PIR,BCL6,HSCB,HDAC6,ITGB8,FCGR2B,PKNOX1,BATF,STK11,MMP21,TNF,LMBR1L,TWSG1,RBPJ,IL10,TMOD3,RLIG1,TESPA1,TUSC2,EEF2,TFRC,CMTM7,PRKX,NDP,CEBPG,TRAF6,G6PD,TLR2,TSPO2,CCR2,VPS54,IRF4,NHEJ1,CCL19,STAT5A,RHOH,XRCC5,BPGM,SLC11A2,GLRX5,HCLS1,FOS,PML,ARMC6,RAG1,TAFAZZIN,WBP1L,IL15RA,SLC25A5,RB1,GPR89A,RAC2,KLF3,NKAP,EXT1,ANGPT1,CIAO3,LARGE1,PTPN11,DCLRE1C,KLF4,LRRC8A,CD40LG,LEP,TLR4,ATF4,CDK6,PAFAH1B1,TENT2,SNX10,IFNG,TP53,STK4,IL21,AZI2,MITF,ETV6,LEPR,SOD2,SLC39A7,CD3G,PIK3R2,KLF1,TPD52,PIK3R1,TRIM10,CCDC134,CHMP5,IRF1,MLF1,PPARG,LIPA,IFI16,UFL1,RACGAP1,OSTM1,PTGER4,SRP54,IL15,FBXO7,EPO,PDE1B,SFXN1,EGR1,VEGFA,B2M,YTHDF2,KDELR1,EZH2,IL3,ITK,IL7 |
| 2.256e-03 | -6.09 | Signaling by Leptin | REACTOME pathways | R-HSA-2586552 | 253 | 101 | 10285 | 3229 |
BRAP,CSK,DLG4,PSMA2,PSMB6,PSMB10,IL2,FGFR1,PSMC5,PSMB11,PSMA4,PSMC4,PSMA3,PSMB5,PSMB1,JAK2,PSMB7,PSMD3,PPP2R1A,STAT5A,UBB,PTPN11,PSMD14,FGF17,PSMD7,ANGPT1,PSME1,LEP,PPP5C,SPTBN1,RAP1A,SHC3,PSMD12,FGF7,JAK1,CSF2,NEFL,DUSP10,MAP3K11,IL2RA,SPRED2,PSMB9,HBEGF,PSMD6,PSME2,FGF3,PSMB3,PEBP1,PPP2R5E,SPTAN1,PSMA5,FGF23,PAQR3,MET,PPP2R5A,FGF1,DUSP6,YWHAB,SOCS3,IL2RG,RAF1,WDR83,UBA52,FGF22,KRAS,MAP2K1,RAP1B,FGF10,DUSP9,SRC,PSMD10,FRS3,PSMA6,PEA15,PSMB2,PSMD1,IL5,HRAS,KIT,LAMTOR2,PPP2CB,CUL3,PSMC1,LEPR,VWF,CAMK2G,LAMTOR3,IL2RB,FGF16,SPRED1,PSMD4,PHB1,IL3,RPS27A,PSMA1,PSMC3,DUSP1,SEM1,PSMB4,SHC1,RASGRP3 |
| 2.262e-03 | -6.09 | cytokine activity | molecular function | GO:0005125 | 238 | 92 | 18094 | 5411 |
CXCL12,ADIPOQ,IL34,IL10,IL2,IL4,CCL19,CCL23,IFNK,CCL8,IL1B,CSF2,NDP,CCL27,CCL20,CX3CL1,IL23A,CCL3,IFNG,GH1,MSTN,CXCL3,GREM2,TNFSF13,INHA,CCL24,BMP1,CCL5,CCL17,IL15,IL7,ALKAL1,IL3,IL22,IL17F,FAM3C,TGFB3,IFNA10,CCL11,TIMP1,XCL1,TNFSF18,GREM1,IL13,CCL2,CER1,IL21,IL12A,TNFSF10,CXCL10,LTB,CXCL9,LTA,TNFSF12,IL12B,CXCL8,WNT7A,CXCL1,MIF,SPP1,CCL25,WNT2,IL6,OSM,CKLF,EPO,TGFB2,CCL4L1,SCG2,MSMP,WNT10B,VEGFA,CCL1,IFNB1,TNF,CXCL11,CCL28,TNFSF15,TNFSF8,CXCL13,CXCL14,FASLG,IFNA2,IL5,CD40LG,CCL21,CMTM7,IL1A,IFNA13,IL18,HMGB1,CCL18 |
| 2.272e-03 | -6.09 | cellular response to acetylcholine | biological process | GO:1905145 | 43 | 22 | 18204 | 5365 |
CHRM5,CDK5R1,OPRM1,CRKL,PLCB1,RGS10,GNB1,LARGE1,GNAI2,LY6H,HRH3,PRKCB,CHRM3,CHRM4,GNAQ,CHRNA7,CHRNB2,GNA11,ATP2B4,ACHE,CHRM1,ROCK2 |
| 2.279e-03 | -6.08 | Cytosolic sensors of pathogen-associated DNA | REACTOME pathways | R-HSA-1834949 | 68 | 33 | 10285 | 3229 |
POLR3B,HMGB1,IKBKB,EP300,MYD88,TBK1,NFKBIA,POLR1D,POLR2F,CTNNB1,UBB,POLR3H,POLR2L,UBA52,RPS27A,XRCC5,TRIM32,TLR3,TRIM21,POLR3GL,NFKBIB,CGAS,S100B,CREBBP,IRF3,POLR3F,AGER,IRF7,NFKB1,STAT6,TICAM1,DHX9,IFI16 |
| 2.281e-03 | -6.08 | MAP7 (microtubule associated protein 7) | protein interactions | 9053 | 234 | 86 | 19454 | 5460 |
EHD4,MAP1B,DHX9,CSE1L,MEPCE,TBK1,IPO8,CTDSP2,RPL15,GNPDA2,NEFL,OTX2,SSBP1,ALYREF,CDC5L,MOV10,GPRASP2,HDAC6,KLHL22,CCL4L1,BAP1,TWNK,CLK1,SQSTM1,PIAS1,CCL3,GRM2,MMADHC,HEXIM1,RPL26L1,TRIM36,FBLN5,TRIM27,GSK3A,VIRMA,SRPK2,ANAPC15,CCDC22,ZBTB38,ELAVL2,MAPRE1,UBE2H,CASC3,S100B,MRFAP1L1,FBXO11,FHL3,TUBA1A,TNPO2,KIF2A,TUBB4B,PNMA2,CHMP4C,SRSF1,PPP2CB,KRT8,SNX17,INA,VPS26A,SAV1,YWHAG,YWHAH,ACTL6B,WDR11,DDRGK1,CAMSAP2,YWHAB,NGRN,LCA5,EP300,PSENEN,FXR2,FTL,EHHADH,EHD1,MED23,PNMA1,FAM91A1,TAX1BP1,TNPO3,APEX1,MYC,HNRNPC,FYTTD1,YWHAZ,COP1 |
| 2.282e-03 | -6.08 | regulation of cysteine-type endopeptidase activity | biological process | GO:2000116 | 194 | 76 | 18204 | 5365 |
HTRA2,MIR17,CSNK2A1,NLRP3,IFT57,FAS,MCL1,ANP32B,IFI16,CAAP1,DNAJB6,MIRLET7B,SFN,FIS1,PAK2,PPARG,CTSD,RPS27L,HSPE1,IGBP1,ARL6IP5,BCL2L1,JAK2,BCL2A1,PMAIP1,PSMB9,CDKN2D,VEGFA,CRADD,PIH1D1,DAP,BAD,NLRP2,PDCD5,HMGB1,SYK,FAM162A,NLRP1,SOX2,SRC,TNFSF15,HSPD1,AKT1,BCL10,AIFM1,SIAH2,NKX3-1,KLF4,S100A8,KHDC1,PYCARD,RNF34,FASLG,IFI6,DPEP1,CST3,ACVR1C,TNF,TNFSF10,RAF1,SMAD3,MUL1,BOK,BAX,MYC,CLEC7A,BAK1,MMP9,DAPK1,LAMP3,MIR15A,RPS3,EGLN3,GPX1,BIRC2,CYFIP2 |
| 2.293e-03 | -6.08 | RNA polymerase II general transcription initiation factor activity | molecular function | GO:0016251 | 40 | 21 | 18094 | 5411 |
SNAPC1,GTF2A2,GTF2F2,TAF2,GTF2H2,GTF2E2,GTF2B,SNAPC5,DRAP1,TAF10,GTF2F1,TAF9,PAAF1,TAF11,TAF7,GTF2E1,CCNH,GTF2H4,DR1,GTF2A1,SNAPC2 |
| 2.295e-03 | -6.08 | SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1) | protein interactions | 57522 | 37 | 19 | 19454 | 5460 |
FBXW7,VIRMA,PEG10,PSPC1,PTEN,SKA1,YWHAZ,SNRNP70,CD9,CDK8,YWHAB,ARHGAP1,FASLG,WDR77,BMPR1B,KLHL22,YWHAG,CDC42,YWHAH |
| 2.295e-03 | -6.08 | RUSC2 (RUN and SH3 domain containing 2) | protein interactions | 9853 | 37 | 19 | 19454 | 5460 |
KLC2,GIT2,YWHAB,YWHAZ,YWHAG,XPO1,YWHAH,CDKN1A,PPP1CC,NFE2L1,ATG16L1,ATG9A,SFN,MSH6,RAB1B,HAPSTR1,SRPRA,RAB1A,DLST |
| 2.295e-03 | -6.08 | NCOA7 (nuclear receptor coactivator 7) | protein interactions | 135112 | 37 | 19 | 19454 | 5460 |
GABPA,STX6,STX7,CAV1,ATP6V1G1,GABARAP,ESR2,RAB35,RAB9A,RAB5A,LAMTOR1,FGFR1,RHOB,RAB4A,ATP6V1D,LAMP2,LAMP3,YWHAH,DIRAS1 |
| 2.295e-03 | -6.08 | PGAM4 (phosphoglycerate mutase family member 4) | protein interactions | 441531 | 37 | 19 | 19454 | 5460 |
PDCL,RIT1,CCT2,PPM1B,CFTR,DDRGK1,PGAM1,CFAP20,CCT5,CCT7,TFEB,UFL1,BPGM,TCP1,HEY2,IL2RA,GPX4,GRXCR1,CCT8 |
| 2.295e-03 | -6.08 | NSG1 (neuronal vesicle trafficking associated 1) | protein interactions | 27065 | 37 | 19 | 19454 | 5460 |
PDZK1IP1,STX12,TM4SF18,RELL2,RPN1,FCGR2A,OPRM1,OST4,ATP6AP2,SRPK2,TMEM45B,DEFB129,FNDC9,SLC7A14,MGST3,BSCL2,CYB5R3,TMX2,SLC23A2 |
| 2.295e-03 | -6.08 | TXNL4B (thioredoxin like 4B) | protein interactions | 54957 | 37 | 19 | 19454 | 5460 |
ZBTB2,NOB1,PLEKHF2,KRAS,HNRNPL,AIPL1,FBXW7,PICK1,ALKBH4,RPS3,BHLHE40,BRD3,SNRPE,RIOK2,XPO1,SPG21,ZMYM4,PNMA5,EMC4 |
| 2.295e-03 | -6.08 | CCN1 (cellular communication network factor 1) | protein interactions | 3491 | 37 | 19 | 19454 | 5460 |
SMPD2,RHOG,RAB4A,ADAMTS1,RHOB,ITGB5,COP1,MYC,NOTCH2,SFN,CDC42,SOX2,CFTR,TRIM37,CGAS,ITGAV,CNTROB,DYRK1A,LMBR1L |
| 2.295e-03 | -6.08 | IL2RG (interleukin 2 receptor subunit gamma) | protein interactions | 3561 | 37 | 19 | 19454 | 5460 |
JAK1,STAT5A,STAT1,JAK2,ERRFI1,IL2RB,GRB10,WWP2,STK4,IL15,IL7,IL15RA,IL4,SHC1,WWP1,ICAM1,IL21,REEP6,IL2 |
| 2.301e-03 | -6.07 | glycosphingolipid biosynthetic process | biological process | GO:0006688 | 38 | 20 | 18204 | 5365 |
GAL3ST1,ST3GAL5,FUT1,ST6GALNAC3,B4GALT4,CERK,ST8SIA5,B4GALT3,LARGE1,B3GALT2,FUT9,B3GALT1,ST8SIA4,FA2H,ST3GAL2,B3GALT4,B4GALT6,UGCG,B3GALNT1,ST3GAL1 |
| 2.302e-03 | -6.07 | LSM8 (LSM8 homolog, U6 small nuclear RNA associated) | protein interactions | 51691 | 98 | 41 | 19454 | 5460 |
SNRPB,MYC,GMPPA,LSM3,MAP4,YWHAB,RIT1,USP15,RPL24,LSM6,SMU1,SNRPD1,CCNF,ALYREF,RPL32,RBM5,RSL24D1,KCTD3,SNRPD3,LSM5,SOX2,DDX39A,SNRPN,RPL26L1,HEXIM1,MTA2,SNRPE,SART3,NUPR1,USP39,LSM2,PPIH,DPAGT1,BCKDK,PRPF4,MEPCE,OLA1,NME4,LSM4,KRAS,GTF2I |
| 2.302e-03 | -6.07 | GNAO1 (G protein subunit alpha o1) | protein interactions | 2775 | 98 | 41 | 19454 | 5460 |
HAX1,MED4,SNX5,CRHR1,HDAC6,GNG2,BAG3,OPRM1,RAB11A,VIRMA,GNAI2,GNB1,SNX1,ACTB,SNX2,RGS10,RGS1,GNAO1,RGS5,ARMC1,ACTA2,GNAI3,TFCP2,NGB,DRD3,METTL14,GPR35,TSHR,GNG3,GNG10,DUSP22,KLHL3,ADORA1,RGS19,GABBR1,CERS2,ZBTB16,GPM6A,SLC16A1,HADHA,CCR5 |
| 2.302e-03 | -6.07 | Snd1 (staphylococcal nuclease and tudor domain containing 1) | protein interactions | 56463 | 98 | 41 | 19454 | 5460 |
RPL8,CCNF,CTTN,EIF4A3,ENO1,GSK3A,PTEN,ACTB,PRRC2A,HNRNPA1,BTF3,JPT1,BTF3L4,NONO,CHORDC1,RPL24,IGF2BP1,MAP4,RPL23,PYM1,CCT8,HNRNPA2B1,RPL23A,RPAP3,LSM12,RPL3,MTDH,DHX9,G3BP1,FXR2,HNRNPA0,RUVBL1,RPL28,CHMP2B,G3BP2,CCT5,TP53,EEF1A1,NUFIP2,EIF4B,JPT2 |
| 2.302e-03 | -6.07 | PRPSAP2 (phosphoribosyl pyrophosphate synthetase associated protein 2) | protein interactions | 5636 | 98 | 41 | 19454 | 5460 |
SNRNP27,MAP1LC3B,CDC42,ELK4,FNTB,CDK7,TPT1,PRKCA,CAV2,RPA2,PRPSAP1,MTDH,RTCB,RAB5A,RPA3,BAP1,PEBP1,SSRP1,PRPS1,HSPA5,NAPG,COPS5,CCNB1,EMC4,CBL,NAPA,UBE2H,USP15,IVNS1ABP,NCK1,PSMD10,CCNF,SH3BGRL,RPL19,WIF1,SNRPB2,CAV1,VTI1B,DCUN1D1,TOP1,PRKCE |
| 2.303e-03 | -6.07 | synaptic vesicle membrane | cellular component | GO:0030672 | 132 | 54 | 19108 | 5553 |
SYNGR4,SYPL1,DNAJC5,RAB5A,STX10,CPLX3,STX12,ATP8A1,RAB11B,RAB3A,SYNGR2,SLC18B1,SCAMP5,STX6,ICA1,SLC4A8,GRIA1,GAD2,SV2B,BORCS5,RAB5C,SYN3,SYT2,ATP6V1D,ATP6AP2,RAB3C,GABRA2,SLC35G2,SNAPIN,STX1A,ATP6V1G2,VAMP2,ATP6V1C1,SVOP,STX16,ZNRF1,OPRK1,VAMP1,SEMA4C,SLC35F1,SLC32A1,RAB3B,SYNGR1,ATP6V1G1,SYP,SLC17A5,PRRT1,SYNPR,BCL2L1,LAMP5,SYNGR3,SYT4,ATP6V1A,SYNDIG1 |
| 2.303e-03 | -6.07 | exocytic vesicle membrane | cellular component | GO:0099501 | 132 | 54 | 19108 | 5553 |
GABRA2,RAB3C,SNAPIN,SLC35G2,STX1A,VAMP2,ATP6V1G2,SYN3,BORCS5,RAB5C,SYT2,ATP6V1D,ATP6AP2,SCAMP5,SLC18B1,STX6,RAB3A,SYNGR2,GAD2,SV2B,ICA1,SLC4A8,GRIA1,RAB5A,SYNGR4,SYPL1,DNAJC5,RAB11B,ATP8A1,CPLX3,STX10,STX12,BCL2L1,ATP6V1A,SYNDIG1,SYNGR3,LAMP5,SYT4,SLC32A1,ATP6V1G1,SYNGR1,RAB3B,SLC35F1,SLC17A5,SYNPR,PRRT1,SYP,VAMP1,SEMA4C,ATP6V1C1,STX16,SVOP,OPRK1,ZNRF1 |
| 2.303e-03 | -6.07 | EPHA7 (EPH receptor A7) | protein interactions | 2045 | 281 | 101 | 19454 | 5460 |
PSMB4,WDR6,TNIK,RAB35,MAP1LC3A,ADGRG1,RHOH,OCRL,PCSK9,NPC2,DIRAS3,PIK3R1,CTNNB1,RHOG,RPL23,TMEM30A,SLC39A7,PICK1,MYO1B,EFNB1,EPHA4,KRAS,LAMB2,POLDIP3,AHCYL1,B3GNT2,SOX2,TUBA1A,RPN1,PLS3,HGS,OAF,TUBB,BMP1,MANSC1,MB21D2,NCKAP1,GNB1,EFNA5,PKP4,NIBAN2,MBLAC2,RHOB,LAMTOR1,NTRK3,DNAJC3,HADHA,DUSP26,CYFIP2,EMC1,NOTCH2,USP6NL,TMEM231,LNX2,PSMB7,ARCN1,EHBP1,EFNA3,PSMB1,RAC2,SEC23A,CDCA3,FCHO2,ARF6,CAV1,DPP4,DLG1,ART5,PC,CTNND1,NHERF1,CASK,CTNNA1,GXYLT1,RHOJ,COPE,FERMT2,PTPN11,RAB2A,NPTX1,DNAJC5,GORASP2,EPHA2,BANF1,SEPTIN6,LIN7C,RHOU,FTSJ1,PIK3R2,YKT6,HSPA5,DUSP18,NTPCR,GP9,SLC12A2,ZNF267,JUP,SDCBP,AGAP1,CHPF2,AVPR1B |
| 2.311e-03 | -6.07 | atypical_ductal_hyperplasia | COSMIC cancer mutations | atypical_ductal_hyperplasia | 24 | 14 | 16828 | 4835 |
PTEN,FGFR1,PIK3CA,JAK2,PTPN11,AKT1,FBXW7,MET,KIT,CTNNB1,TP53,GNAQ,HRAS,KRAS |
| 2.311e-03 | -6.07 | breast-hyperplasia-atypical_ductal_hyperplasia | COSMIC cancer mutations | breast-hyperplasia-atypical_ductal_hyperplasia | 24 | 14 | 16828 | 4835 |
GNAQ,HRAS,KRAS,PTEN,PIK3CA,FGFR1,FBXW7,JAK2,PTPN11,AKT1,TP53,MET,KIT,CTNNB1 |
| 2.311e-03 | -6.07 | ganglioglioma | COSMIC cancer mutations | ganglioglioma | 24 | 14 | 16828 | 4835 |
GNAQ,KRAS,KLF4,IDH1,TERT,PIK3CA,SMARCB1,PTEN,GNA11,CTNNB1,TP53,ETV6,AKT1,IDH2 |
| 2.315e-03 | -6.07 | PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha) | protein interactions | 5576 | 197 | 74 | 19454 | 5460 |
RMDN3,LMBR1L,CCNF,LRIF1,DYRK1A,VIRMA,ESR2,RHOJ,DYNLL1,TAX1BP1,ADRM1,PRKACB,KPNA6,DNAJC5,CUL3,FIS1,NAPA,MAPRE1,CIRBP,STK24,MAVS,AKAP1,BAP1,RPA3,EXD2,FOS,CSRP1,PXMP2,TOMM20,HSPA5,SMC4,PPP1CB,CFTR,TOMM22,SCLT1,PRKCA,ACACA,PSMB7,CDK1,RPA2,PTPN22,METTL14,PTPN1,SMAD3,AIFM1,MYL12A,EGLN3,SRSF10,PRNP,XPO1,HP,PRKX,RAB32,SLC25A46,MARCHF5,CBL,RHOG,SMAD4,PSMD7,AKAP14,PRDM4,ABCE1,SEMG2,PALM2AKAP2,VTA1,FKBP8,AKAP12,TF,PPP2R1A,CSNK1E,ARFGEF1,MTCH2,MOB3C,TUBB4B |
| 2.315e-03 | -6.07 | CCDC137 (coiled-coil domain containing 137) | protein interactions | 339230 | 197 | 74 | 19454 | 5460 |
RPS11,RBM34,TAF1D,RPSA,RPL17,H1-6,HMGN4,RPL3,RPL23A,RPS24,RPL31,NOL12,RPS2,RSBN1L,RPL10A,MRPL18,SNRNP70,DDRGK1,GRSF1,IFI16,WWP2,ZNF24,SURF6,RPS16,FZR1,RPS10,LYAR,HP1BP3,RPL8,SYNCRIP,SRP14,RPL32,KRR1,SRSF1,RPL26L1,RPLP0,ZNF770,GRM2,RPS14,BRIX1,NPM3,DGCR8,FBXW7,STAU1,RPL4,NOP53,RPA3,RCCD1,NLE1,H1-1,NSA2,FYTTD1,RC3H2,FTSJ3,ZNF668,RPL26,RPF2,MYC,RPL7A,SRPK2,RPL10,RPL19,RPL13A,RPL35,RPL7L1,RPF1,ZCCHC7,PRKRA,FGFBP1,RPL37A,RPS9,CCNF,ZNF22,ZNF330 |
| 2.316e-03 | -6.07 | ubiquitin-like protein binding | molecular function | GO:0032182 | 123 | 52 | 18094 | 5411 |
KLF1,PML,HDAC6,SOBP,CXCR4,HSPB1,USP13,FBXW7,RNF8,VPS28,DNAJB2,USP16,DNAAF10,TRIM32,TOM1L1,TSG101,UBE2A,RBCK1,BIRC2,UBE2N,OTULINL,ZFAND2B,TP53INP2,DHX16,FBXO7,TAB2,BUB3,MDM2,SMAD3,UCHL3,UBXN10,UBXN2B,PLAA,UBAP1,TOM1L2,CKS1B,USP5,FAF2,DCUN1D5,TOM1,SQSTM1,HGS,NUP62,PELP1,TOLLIP,FAF1,DCUN1D3,TNFAIP3,DCUN1D1,RAD23B,CKS2,NSFL1C |
| 2.319e-03 | -6.07 | negative regulation of RNA metabolic process | biological process | GO:0051253 | 1381 | 454 | 18204 | 5365 |
FABP4,IFNA2,CDC73,MSX2,WDR82,DNAJB6,SFN,NACC2,RPL10,SYNCRIP,ZBTB16,ZNF24,E2F6,HDAC3,PLCB1,KCNIP3,FOXD3,TCF21,POU5F1,IREB2,SRSF10,CD36,BAP1,TXNIP,WNT10B,FOXS1,ZBTB33,SIN3A,PAX6,IFI27,LYAR,MAD2L2,PPARA,TENT4A,SMARCE1,ZNF263,MTA3,DMAP1,CBX3,HMX1,ENO1,FOXP3,COPS2,JUN,MORC2,SOX21,PAIP1,BAHD1,IL6,ID4,RFX5,TRAF3IP2,ZBTB2,USP2,LDB2,PCBP4,NKX3-2,MAGEC2,FOXP1,THRAP3,NCOA5,HNRNPAB,TRIM24,AR,UBE2D1,PHF21A,HIRA,CCND1,LMO4,CREBZF,DEDD,ABCE1,CRY1,TIRAP,NR1H2,USP3,STAT1,MCPH1,PHC1,MAF1,TSG101,E4F1,SMAD4,PRMT5,DUSP26,SIAH2,NOP53,GMNN,ZMYND11,EID2B,ELAVL4,CCND3,MXI1,VDR,TXN,MAX,BACH1,CTNNB1,RBBP4,SP2,CALR,OVOL1,SIRT7,TCF23,CNOT2,SAP30,EP300,DKC1,DR1,TCEAL7,CTNNBIP1,CRYM,NIBAN2,SOX14,CIPC,ELK4,MYT1L,IFI16,YWHAZ,INSM2,FOXP2,MAGED4B,IRF1,BRMS1,NR0B1,CUL3,GTF2IRD1,NR2E1,SRSF4,CCAR1,SATB1,VEGFA,MTA2,DRAP1,MECP2,NUDT16,DNAJB4,SOX3,NSMCE3,PRMT6,LEP,HNRNPK,FASLG,SQSTM1,HNRNPA2B1,ATF4,HEXIM1,EID1,ZNF175,PHB2,SMARCA5,PPID,ELK3,KLF3,NRDE2,CCDC85B,H1-3,ETV6,PHAX,MEF2A,SUPT4H1,PDCD4,HOXB8,CBX7,APEX1,IFNG,ZBTB5,TENT2,BIRC5,ZBTB39,VIP,PLAGL1,XRCC5,PIAS1,ZBTB25,RPS13,TRAF6,GADD45A,C1D,CD38,APOBEC3A,PABPC1,NFKB1,SNAI3,PDE2A,CIART,RBM42,POU1F1,PML,HCLS1,PSPC1,PSMC5,IGF2BP1,IRF2BPL,CCAR2,APOBEC3C,NOG,HDAC6,SGF29,MAGEB1,NKX3-1,ATF3,KLF10,TMBIM6,BOLL,MACROH2A2,HNRNPL,NR1I3,SETD5,RASD1,IRF2BP1,MAGEA4,HNRNPD,DUSP22,SMAD3,MAGEB10,SCML2,NIF3L1,NR2F6,PSEN1,NKRF,LILRB4,SCML1,ZBTB42,ZHX1,ZGLP1,APOBEC3F,UBE2I,BRCA1,IL4,WWP1,MYD88,SMAD2,ZMPSTE24,RUNX1,ZMYM2,GFI1,THAP1,BEND6,PKIG,ING2,DKK3,RUVBL2,ZCCHC17,BEND5,MEF2C,LANCL2,CBFB,VGLL4,RBFOX2,ZBTB17,RBBP8,TRIM11,CAV1,MEPCE,KLF12,MAGED2,SRSF12,CDK5R1,HEY2,EED,BARX2,IRF3,NFIL3,TGIF2,CSF2,SMAD5,OSR2,INPP5K,APOBEC3D,HNF1B,ID1,CRYAB,APOBEC3G,FLCN,SFRP1,CREB1,MAGEH1,MYC,WWP2,DLX1,RPS14,MOSPD1,RORB,IGBP1,DLG1,MAFG,IKZF5,DICER1,SNAI2,SOX9,RGN,CIRBP,HNRNPA0,TADA3,DHRS7B,TRIM22,HNRNPC,TWIST2,SUMO1,CTBP1,HDAC5,PRMT2,SHC1,IRF8,ZNF174,TOB2,SAP30L,NR1I2,ZBTB26,KDM1A,TRIM29,MACROH2A1,IRF7,ZNF345,ZBTB18,GREM1,HCFC2,SRSF7,MBD3,MTDH,CREBBP,PROX1,BHLHE40,STAT6,THAP7,RNF8,ZNF177,DYRK1A,HSBP1,DHX9,DKK1,SOX2,TRIM37,GCLC,IRF2,OTUD7B,MXD1,NCK1,TLE1,ZBTB38,RERE,RING1,PCNA,RLIM,NOTCH2,RPL23,APOBEC3H,PPARG,MIDEAS,RBM15B,SUFU,SUV39H1,SLA2,CDKN1B,IMPACT,ZBTB6,BTG2,EZH2,EZH1,RPS26,ESR2,ZBTB14,CNOT7,EGR1,EPO,ZNF668,ZNF692,NR4A2,DDIT3,TRIM27,POLE3,CDK6,NONO,PAX9,TGIF2LX,KLF4,HSPA8,SIX5,PCGF2,HELT,SAP18,FGFR1,ATXN1L,NKAP,PCGF6,UBE2D3,DDX5,ZNF451,VPS72,MITF,TP53,TENT5D,MAEL,TAF7,MDM2,SDCBP,H1-5,FOXC2,CGGBP1,LDB1,ZHX3,TFDP2,RB1,CITED1,DAP,NAB1,ZBTB45,SPINDOC,FBXW11,EID2,PHF12,MDFI,APOBEC3B,SDR16C5,NDN,PSMD10,TENT5C,SUPT5H,RIOX2,PKIA,ZNF304,HINFP,GABPA,FBP1,KDM2A,HEXIM2,CDK5,BCL6,PFDN5,CXXC5,HMG20A,HMGB1,PHB1,ING1,TRIM6,FOXP4,CBX5,MSX1,TRAF2,NKX6-2,TAGLN3,NAB2,FERD3L,XCL1,YAF2,RBPJ,SRSF2,BRMS1L,ADIPOQ,TNF,RBBP7,LBH,HMGA1 |
| 2.338e-03 | -6.06 | cellular response to hormone stimulus | biological process | GO:0032870 | 504 | 178 | 18204 | 5365 |
AKT1,TBC1D4,AIFM1,P2RY4,GCLC,FAM107A,CST11,ADTRP,GRB10,SELENOS,DDIT4,STAT6,PIK3R3,CALR,UCP2,MT3,GPT,OXTR,GH1,GJB2,AGTRAP,MAP1B,PID1,XBP1,GRIA1,GHRL,TADA3,CPEB1,RAB13,ATP1A2,AR,TRIM24,NCOA5,NR1H2,STAT1,PCSK9,CTSB,CAV2,OR51E2,JAK2,EIF4EBP2,UGCG,ACACA,CRHR1,RAMP3,HDAC5,PRKCE,EGLN2,GSK3A,SHC1,CA2,REN,INPP5K,ERRFI1,KLF9,AKT2,PRL,YWHAH,ATP5F1A,PPARA,RXRG,SOS2,RNF14,UBE3A,PELP1,SLC2A8,YWHAG,BGLAP,MIR107,SOCS2,ADIPOR2,PADI2,PTGER2,EIF4E,FBXO32,CSK,IGF1R,AHCYL1,SFRP1,JAK1,PCK2,PLCB1,GNRHR2,RWDD1,GPR22,ATP1A3,IDE,SERPINB9,RBFOX2,USP8,WNT10B,EDNRA,SMYD3,PAX6,CAV1,MEF2C,EFNA5,MSTN,GNB1,HRAS,ADIPOR1,NKX3-1,FBP1,HDAC6,RAF1,PTGFR,CYP11B2,STC1,LHB,ADIPOQ,PHB1,AVPR1B,UBE2L3,CRHBP,ATP1A1,PAQR8,MIR145,RARRES2,CYP1B1,FKBP4,CSNK2B,STAT5A,FOXC2,VPS54,WBP2,VAMP2,FOS,SLC22A12,CYP11B1,RB1,NFKB1,RAB31,PTPN1,SRC,GHR,HSPA8,GNG2,PTGES3,MGARP,TSHR,UGT1A1,SST,TRIP4,CSH1,INSIG2,LEP,TFPI,PHB2,PTPN11,MDM2,PIK3CA,TAF7,LEPR,DDX5,MIR143,SOST,GPR173,PGR,NR2E1,GAB1,RAN,PIK3R1,PIK3R2,CCNA2,SHOC2,PTGER4,RXFP2,MIR493,SP1,PPARG,FGF23,MKKS,ABHD2,NR4A2,AKR1C2,NFE2L2,AKR1C1,ESR2 |
| 2.348e-03 | -6.05 | G-protein beta-subunit binding | molecular function | GO:0031681 | 21 | 13 | 18094 | 5411 |
GNG3,CCT5,GNGT2,OPRM1,GNG5,GNG13,GNG12,GNG11,GNG10,GRIA1,GNG7,GNG2,RASD1 |
| 2.348e-03 | -6.05 | negative regulation of leukocyte migration | biological process | GO:0002686 | 56 | 27 | 18204 | 5365 |
WASL,CCL21,MIF,MMP28,PLCB1,ADORA1,CCL25,DDT,CXCL12,AKT1,EMILIN1,DPP4,GREM1,STAP1,MIR146A,PTGER4,ADTRP,CD200,MIR223,CCL2,CD200R1,CCL28,MIR24-1,TNFAIP6,CCN3,PADI2,DUSP1 |
| 2.348e-03 | -6.05 | response to amyloid-beta | biological process | GO:1904645 | 56 | 27 | 18204 | 5365 |
TNF,MIR106B,IGF1,MIR200C,ICAM1,EPHA4,MIR200A,CD36,IGF1R,RAMP3,CASP4,CHRNA7,MMP9,GJA1,CDK5,BACE1,TLR6,FCGR2B,MIR98,PRNP,ATP1A3,MIR146A,PSEN1,ADRB2,TLR4,AGER,MIR140 |
| 2.349e-03 | -6.05 | Formation of ATP by chemiosmotic coupling | REACTOME pathways | R-HSA-163210 | 16 | 11 | 10285 | 3229 |
ATP5PF,ATP5F1B,ATP5MG,ATP5MC3,ATP5F1A,ATP5PO,ATP5F1E,ATP5PB,ATP5F1D,ATP5MC1,ATP5PD |
| 2.349e-03 | -6.05 | Translesion synthesis by REV1 | REACTOME pathways | R-HSA-110312 | 16 | 11 | 10285 | 3229 |
RPA3,PCNA,RFC2,RFC5,MAD2L2,RPS27A,UBA52,RFC3,RFC4,UBB,RPA2 |
| 2.349e-03 | -6.05 | LRP8 (LDL receptor related protein 8) | protein interactions | 7804 | 78 | 34 | 19454 | 5460 |
ATG16L1,MYLIP,RAB4A,RAB9A,RAB5A,VLDLR,CLU,STX7,RAB3B,KRAS,SLC31A1,LAMP3,RAB11A,RAB5C,CUL3,LAMP2,MOV10,SYNJ2BP,RAB2A,SLC7A11,HNRNPD,NOS1AP,RHOB,LAMTOR1,KRT8,SNX17,ALB,DLG4,PRCC,CAV1,VIRMA,ARF6,HNRNPL,SPPL3 |
| 2.349e-03 | -6.05 | TTC13 (tetratricopeptide repeat domain 13) | protein interactions | 79573 | 78 | 34 | 19454 | 5460 |
LMBR1L,RMDN3,DNASE1L1,SEC61B,DNAJB9,DNAJC1,EGLN3,CD1A,SEC63,FIBIN,CSK,DPP4,CFC1,GGH,PPP1CC,SDF2L1,DNAJC10,LYZ,DNAJC3,TMEM106B,IGF1R,CLEC12B,GPIHBP1,FKBP2,HSPA5,CCDC47,B3GNT2,BRINP1,TMEM106A,DNAJC25,CBLN4,SFTPC,PLD3,NCR3 |
| 2.349e-03 | -6.05 | IFIT3 (interferon induced protein with tetratricopeptide repeats 3) | protein interactions | 3437 | 78 | 34 | 19454 | 5460 |
HNRNPDL,RIGI,ATP1A2,MAVS,SNRPA,PSEN2,HNRNPA2B1,MYH2,PABPC1,SNRPE,CYP2C8,TRAF2,ISG15,TBK1,SNRPB2,HNRNPL,TXN,CGAS,SNRPA1,SNRPD3,SNRPD2,SNRPD1,IFIT2,HNRNPD,IFNA2,TRAF6,SNRNP70,TMEM183A,HNRNPA1,SNRPB,TPM3,MOV10,PYCR1,HNRNPAB |
| 2.349e-03 | -6.05 | ALDH9A1 (aldehyde dehydrogenase 9 family member A1) | protein interactions | 223 | 78 | 34 | 19454 | 5460 |
PYGB,PSEN1,RPA3,BAP1,CRY1,ACAA2,PTRH2,PDHA1,VPS33A,RPA2,PLS3,NUFIP2,KBTBD4,SOX2,GMDS,BCCIP,RABIF,CHMP2A,DYRK1A,HDHD5,STUB1,USP46,BRCA1,YWHAZ,UBXN10,DDX1,DNAJC7,TNFAIP3,MYC,DNAJC5,HMOX2,ATG101,COPS5,BFAR |
| 2.349e-03 | -6.05 | ZEB2 (zinc finger E-box binding homeobox 2) | protein interactions | 9839 | 78 | 34 | 19454 | 5460 |
SMAD3,ELK3,CSNK2B,PHF21A,UBE2I,RBBP4,SMAD5,VIRMA,HNF1B,CSNK2A1,SMAD2,SMAD9,LHX2,RPA3,EP300,KDM1A,RBBP7,HDAC3,TRIM37,FBXW7,MBD3,RIGI,PAX6,SUPT5H,EGR2,SOX2,KLF12,SMAD1,CTBP1,KLF3,EZH2,RPA2,MTA2,KLF4 |
| 2.351e-03 | -6.05 | TMEM11 (transmembrane protein 11) | protein interactions | 8834 | 101 | 42 | 19454 | 5460 |
FATE1,DDRGK1,SUV39H1,FAM174A,SLC25A46,TSPAN10,MOV10,NTRK3,PDZK1IP1,RIC3,CYB561,CD226,YWHAZ,TMEM106C,CD4,CLN8,RETREG3,ELOVL4,DUSP6,CCNF,TMEM237,MSMO1,CX3CL1,RNASEH1,DUSP22,TMEM205,ADORA3,OTX2,TMEM14B,NDUFS3,LMNA,SDC2,CYB5D2,TMEM88,DUSP9,CCR4,BNIP3L,LEPROTL1,TACR3,LPAR1,UFL1,SLC7A1 |
| 2.351e-03 | -6.05 | CPNE8 (copine 8) | protein interactions | 144402 | 101 | 42 | 19454 | 5460 |
SSR1,RAB4A,RND3,RAF1,RND2,CDC42,RAB3B,KRAS,EPHA4,FLOT1,LSM8,OGDHL,STX7,TMT1A,RHOU,SNAPC1,TMEM185A,RAB5A,SRSF7,RAB9A,RHOB,LAMTOR1,RHOG,NRP1,LAMTOR2,RAB11A,MOV10,LAMP2,DNAJC5,RHOH,RHOJ,ARF6,APEX1,CAV1,DIRAS3,STX6,CTDSPL2,HRAS,RAB35,SEC61B,RAC2,GJA1 |
| 2.355e-03 | -6.05 | G alpha (i) signalling events | REACTOME pathways | R-HSA-418594 | 242 | 97 | 10285 | 3229 |
HTR1F,TAS2R39,ADCY2,MCHR2,CCL20,OPRK1,TAS2R46,NPB,CXCR4,CXCL1,ADCY3,CCR1,APLNR,NPW,CCL19,RGS19,CXCL8,GNG7,CCR3,CXCR3,CXCL13,GNG2,RLN3,GNG12,GNG3,HCAR1,CXCL3,OPRL1,CCR7,APLN,LPAR2,NPY5R,CXCR6,RGS6,TAS2R16,TAS2R40,GNAI2,GNB3,GNGT2,CHRM4,S1PR4,P2RY12,CXCR1,TAS2R5,GNB4,GRM8,CCL25,GPR17,MCHR1,CCL23,ADORA1,ACKR3,CXCL10,CCL28,GNG13,DRD3,GNG10,RGS10,GNG5,TAS2R7,CCL5,NPY2R,CCL21,P2RY4,LPAR1,CCL27,GABBR1,GNB1,TAS2R13,PPY,RGS5,SST,CXCL11,NPBWR1,GNAI3,HEBP1,CCR4,GNG11,CCR6,CCR2,CCR5,ADORA3,HTR1A,GNAZ,NPY1R,OPRM1,PNOC,GRM2,HRH3,RGS1,CXCL9,NPY,CXCL12,CNR1,MIR197,PDYN,HTR5A |
| 2.357e-03 | -6.05 | positive regulation of protein localization to membrane | biological process | GO:1905477 | 105 | 45 | 18204 | 5365 |
STAC3,AKT1,NLGN2,EPHA2,RHOG,CDK5,AKT2,KCNJ11,PIK3R1,PDCD5,RANGRF,ZDHHC8,CDK5R1,STOM,ATP2C1,HRAS,CD81,DLG1,SQSTM1,CRKL,ARF6,PRNP,CLIP3,FIS1,AGR2,CHP1,DPP10,IFNG,ATP2B4,LGALS3,SPTBN1,KCNB1,PIK3CA,RER1,TNF,PGRMC1,MIR223,MIEF1,TNFAIP6,RAMP3,CNPY4,HPCA,EFCAB7,TCAF2,PRKCE |
| 2.358e-03 | -6.05 | ZFYVE1 (zinc finger FYVE-type containing 1) | protein interactions | 53349 | 53 | 25 | 19454 | 5460 |
ACAA2,MRPL49,CYC1,SPC24,UQCRC1,GLRX5,VDAC1,STAU1,RPS27A,ATP6V1G1,DNAJC3,CLPB,BCL2L1,H1-1,CUL3,EDEM1,XPO1,MAGOHB,UBB,SUCLG2,AIFM1,OPTN,OCIAD2,WDR45,BST2 |
| 2.358e-03 | -6.05 | XXYLT1 (xyloside xylosyltransferase 1) | protein interactions | 152002 | 53 | 25 | 19454 | 5460 |
MOV10,MYC,CUL3,SCN3B,FAM20C,NDUFB8,USP15,SEC61B,GXYLT1,CCNF,LMBR1L,EGLN3,TNPO3,HNRNPL,MPP1,SPG21,BORCS6,TOP3B,NOTCH2,PLAA,IZUMO1,RPA2,RPA3,TMEM106B,DCP2 |
| 2.358e-03 | -6.05 | GRM1 (glutamate metabotropic receptor 1) | protein interactions | 2911 | 53 | 25 | 19454 | 5460 |
OPTN,CDK6,GRM1,TUBB,HOMER1,SRC,MYC,OPRM1,GAPDH,TRPC1,BECN1,EPHA2,STK11,CDKN2C,IGF1R,TERT,NF2,STAU1,RAF1,SYK,ADORA1,CDK4,KDELR2,ZMYM3,PRKCA |
| 2.358e-03 | -6.05 | EIF1B (eukaryotic translation initiation factor 1B) | protein interactions | 10289 | 53 | 25 | 19454 | 5460 |
HEBP2,GRSF1,ELOC,EIF3D,RPS29,EIF3G,PSPC1,EIF3K,ACAT1,RPS9,FZR1,EIF2S1,TAGLN2,RPS16,MYL12A,ERH,ATG16L1,SPG21,CHMP4C,RPS11,DVL2,RPA3,DHX9,EIF3E,EIF2D |
| 2.358e-03 | -6.05 | PPP1R12C (protein phosphatase 1 regulatory subunit 12C) | protein interactions | 54776 | 53 | 25 | 19454 | 5460 |
PPP1CC,YWHAH,BTF3,YWHAG,RBM17,SFN,YWHAB,YWHAZ,SMAD3,ESR2,THOC1,SOX2,PPP1CB,EHHADH,JPH4,IMP3,BHLHA9,FGFR1,EXOC3,SPECC1L,CORO6,PPP1R12A,PAFAH1B2,FXR2,TNF |
| 2.358e-03 | -6.05 | PLD5 (phospholipase D family member 5) | protein interactions | 200150 | 53 | 25 | 19454 | 5460 |
EIF4A2,ECHDC1,TRIM29,CALML5,MACROH2A1,DNAJC7,HERC4,ST13,PCCB,CSK,ANKMY2,UNC45A,LPCAT3,LYG2,TSPAN7,GDPD3,DNAJB4,TTC1,GNAI3,CRYAB,SERPINA3,CRAT,H1-5,CSNK1E,DUSP14 |
| 2.367e-03 | -6.05 | BICD2 (BICD cargo adaptor 2) | protein interactions | 23299 | 415 | 143 | 19454 | 5460 |
TBK1,ARHGAP12,ACTR1A,ARPC3,NEFL,TFCP2,CAPN2,TAB2,GARRE1,TCEA2,PSME1,RBM41,SEPTIN7,WASL,NUP107,DYNC1I1,CAPZA1,PGAM1,USP2,KLHL9,KXD1,NFKB1,KLHL22,IL17F,USP15,CNN3,TES,FCHO2,PPP1R18,ZBTB2,SLAIN2,FAM161A,PPP1R8,ARHGAP1,ATG16L1,ST7,EDF1,CD2AP,CZIB,RPA2,TFIP11,UBE2M,UBAP1,NCDN,SEPTIN6,RPA3,ORC6,ARPC2,LCP1,LSM12,ELOF1,RBM22,KDM1A,PPP1R2,H2BC9,BICD2,ARFGAP3,EIF3G,CHORDC1,MAPRE1,CCHCR1,XPOT,CTTN,CEP41,YES1,RPP25L,EIF4H,DYRK1A,BCCIP,VIRMA,FERMT2,MACO1,CSNK1E,DPH5,NUP153,RAB6B,GDI2,TUBB4B,PLS3,VPS33A,JPT2,MTMR2,IFT22,NEK9,HSPD1,NUDT5,ZC3H7A,RPAP3,LASP1,EIF2D,POLDIP3,NDC80,DIS3L,XPO1,CAMSAP2,PDAP1,FBXO32,TNIK,KRT8,ATP6V1A,DYNC1I2,OCRL,PAIP1,PRPF18,PAFAH1B1,TANK,SUFU,NUP62,MTMR6,H1-5,BORCS6,RAB6A,VPS18,VAPB,PIH1D1,MFAP1,GAMT,EIF4B,RTKN,TSPAN15,FAM50B,PEBP1,TTC1,YTHDF1,STAU1,FXR2,PPP2R3A,RAB11A,CUL3,TBCE,EPS8,PRPF31,FAS,KIAA1191,H1-1,CBR3,EFHD2,ZMAT2,PHF21A,FAM83B,TAB1,PDLIM3,NCKAP1 |
| 2.369e-03 | -6.05 | intrinsic apoptotic signaling pathway in response to DNA damage | biological process | GO:0008630 | 72 | 33 | 18204 | 5365 |
TNFRSF1B,HTRA2,PIK3R1,EPHA2,MCL1,BRCA1,IFI16,TOPORS,SFN,DDIT4,MSH6,PYCARD,RPS27L,CRIP1,EP300,BCL2L1,POLB,TNF,PML,DYRK2,CDIP1,BCL2A1,MAEL,CIDEB,CDKN1A,TP53,BOK,BAX,BAK1,IER3,BAD,SOD2,NUPR1 |
| 2.370e-03 | -6.04 | DPEP1 (dipeptidase 1) | protein interactions | 1800 | 64 | 29 | 19454 | 5460 |
ILVBL,TLCD4,ASIC1,GJA1,GPR137,ELOVL4,DPEP1,VMP1,ENDOD1,PIGA,SLC30A5,ORC5,NT5C3A,FANCG,RDH11,ACADS,RER1,SMC4,APPBP2,PICK1,FLCN,SEMG2,GPAA1,DHRS7B,GHITM,TMUB2,HPCAL1,TNPO2,HYAL2 |
| 2.370e-03 | -6.04 | TRIML2 (tripartite motif family like 2) | protein interactions | 205860 | 64 | 29 | 19454 | 5460 |
XAF1,KXD1,STN1,MYO6,TSEN54,CCDC92,COP1,CCHCR1,TBC1D25,ZBTB33,TSG101,SUMO2,MTM1,TRIM54,ING5,TP53,NUP62,SNAPIN,CCNH,BORCS5,HGS,TFIP11,CDR2,PML,SIKE1,BLOC1S2,PICK1,ZBED1,POLR1H |
| 2.376e-03 | -6.04 | negative regulation of toll-like receptor 4 signaling pathway | biological process | GO:0034144 | 19 | 12 | 18204 | 5365 |
MIR20A,TAX1BP1,TRIM32,MIR200C,TNFAIP3,LILRA2,MIR149,MIR146A,MIR708,SQSTM1,MIR140,BPIFB1 |
| 2.376e-03 | -6.04 | negative regulation of amyloid precursor protein biosynthetic process | biological process | GO:0042985 | 19 | 12 | 18204 | 5365 |
MIR153-1,MIR147A,MIR31,MIR106A,ITM2B,MIR298,MIR101-1,MIR455,MIR17,MIR20A,ITM2A,AATF |
| 2.376e-03 | -6.04 | polyamine metabolic process | biological process | GO:0006595 | 19 | 12 | 18204 | 5365 |
DHPS,AZIN2,SRM,SAT2,AZIN1,OAZ1,OAZ3,OAZ2,HDAC6,SAT1,ODC1,PAOX |
| 2.382e-03 | -6.04 | regulation of chemotaxis | biological process | GO:0050920 | 209 | 81 | 18204 | 5365 |
OXSR1,SEMA5A,CCR6,CXCR4,CCR7,CDH13,HDAC6,CREB3,AGER,VEGFC,GREM1,STAP1,MPP1,ITGA2,FGF16,FGFR1,HMGB1,YTHDF1,MMP28,RAC2,MIF,CCL3,CCR4,CXCL12,DDT,SCG2,IL12A,FGF10,CCN3,TNFAIP6,P2RY12,IL6,CX3CR1,MIR34A,HSPB1,DUSP1,PADI2,MIR15A,CCL5,CXCL8,GPSM3,TIAM1,LPAR1,MIR223,F7,DUSP3,DEFB124,SMAD3,ST6GAL1,XCL1,CALR,CXCL13,NTRK3,MIR149,DPP4,CCL19,AIF1,CCR2,CYRIB,PTN,CCL21,MET,RARRES2,CCL1,BMPR2,IL23A,SWAP70,MIR16-1,CCR1,VEGFA,MIR424,MSTN,CXCL10,TPBG,USP14,CCL2,TMSB4X,FGF1,IL34,NRP1,TIRAP |
| 2.385e-03 | -6.04 | Jak-STAT signaling pathway | KEGG pathways | hsa04630 | 156 | 71 | 7161 | 2463 |
IFNG,GHR,LEPR,CSF2,IL20RB,RAF1,IL13,JAK1,IFNA2,CISH,OSM,SOCS5,PIAS1,HRAS,IL12A,IL2,IFNK,IL6ST,EP300,IL5,IL23A,IL2RG,MYC,IFNA10,IFNB1,AKT3,STAT2,MCL1,SOCS2,SOCS4,IL6,IL10,IL15RA,GH1,IL3,IL2RA,AKT1,IL4,JAK2,STAT6,PIK3R2,LEP,PIK3R1,IRF9,SOCS3,IFNAR1,CCND1,AOX1,BCL2L1,CREBBP,PTPN11,IFNGR1,IL12B,STAT5A,IL7,IL15,CDKN1A,STAT1,AKT2,EPO,SOS2,PIK3CA,IFNA13,CSH1,IL21,CCND3,PIK3R3,IL22,PRL,CNTFR,IL2RB |
| 2.385e-03 | -6.04 | Jak-STAT signaling pathway | KEGG pathways | ko04630 | 156 | 71 | 7161 | 2463 |
IFNAR1,CCND1,BCL2L1,AOX1,PTPN11,CREBBP,IFNGR1,IL12B,IL3,IL2RA,AKT1,IL4,JAK2,PIK3R2,STAT6,LEP,PIK3R1,IRF9,SOCS3,SOS2,EPO,PIK3CA,IFNA13,CSH1,IL21,CCND3,PIK3R3,IL22,PRL,CNTFR,IL2RB,STAT5A,IL7,IL15,CDKN1A,STAT1,AKT2,IL20RB,RAF1,IL13,IFNA2,JAK1,CISH,OSM,SOCS5,PIAS1,HRAS,IL12A,IL2,IFNK,IL6ST,EP300,IL5,IL23A,IFNG,GHR,LEPR,CSF2,SOCS4,SOCS2,IL6,IL15RA,IL10,GH1,IL2RG,MYC,IFNA10,IFNB1,AKT3,STAT2,MCL1 |
| 2.389e-03 | -6.04 | exogenous lipid antigen binding | molecular function | GO:0030884 | 5 | 5 | 18094 | 5411 |
CD1A,CD1C,CD1B,CD1D,CD1E |
| 2.389e-03 | -6.04 | endogenous lipid antigen binding | molecular function | GO:0030883 | 5 | 5 | 18094 | 5411 |
CD1D,CD1E,CD1C,CD1B,CD1A |
| 2.389e-03 | -6.04 | superoxide dismutase activity | molecular function | GO:0004784 | 5 | 5 | 18094 | 5411 |
CYGB,SOD1,SOD3,NQO1,SOD2 |
| 2.389e-03 | -6.04 | piRNA binding | molecular function | GO:0034584 | 5 | 5 | 18094 | 5411 |
TEX19,PIWIL3,PIWIL2,PIWIL1,PIWIL4 |
| 2.389e-03 | -6.04 | lipid antigen binding | molecular function | GO:0030882 | 5 | 5 | 18094 | 5411 |
CD1D,CD1E,CD1C,CD1B,CD1A |
| 2.389e-03 | -6.04 | oxidoreductase activity, acting on superoxide radicals as acceptor | molecular function | GO:0016721 | 5 | 5 | 18094 | 5411 |
SOD1,CYGB,SOD3,SOD2,NQO1 |
| 2.389e-03 | -6.04 | ornithine decarboxylase regulator activity | molecular function | GO:0042979 | 5 | 5 | 18094 | 5411 |
AZIN1,OAZ1,AZIN2,OAZ2,OAZ3 |
| 2.390e-03 | -6.04 | F-type ATPase, eukaryotes | KEGG pathways | hsa_M00158 | 15 | 11 | 7161 | 2463 |
ATP5F1A,ATP5PO,ATP5MG,ATP5PD,ATP5PF,ATP5PB,ATP5F1D,ATP5F1B,ATP5MC3,ATP5F1E,ATP5MC1 |
| 2.390e-03 | -6.04 | F-type ATPase, eukaryotes | KEGG pathways | M00158 | 15 | 11 | 7161 | 2463 |
ATP5MG,ATP5F1A,ATP5MC1,ATP5PF,ATP5PD,ATP5PO,ATP5F1E,ATP5MC3,ATP5F1B,ATP5F1D,ATP5PB |
| 2.391e-03 | -6.04 | RCC1 (regulator of chromosome condensation 1) | protein interactions | 1104 | 188 | 71 | 19454 | 5460 |
MTPN,FBXO7,CUL3,SPRED1,MYC,MAPRE1,RIT1,LMNB1,SPOP,MACROH2A1,UBE2I,GSK3A,RAN,ENO1,SF3B6,CCNF,SEC63,DDAH2,ESR2,LRIF1,ACTB,SUMO1,ATG16L1,CSNK1A1,LUC7L3,CTBP1,RPA2,CDK1,MTDH,EP300,BAP1,PPM1G,RPA3,B2M,PDHB,CSNK2A1,XPO1,DNAJB2,TLE1,HMGA1,MOV10,FOXP1,BRD3,H2AC4,AGR2,SLC25A28,CD274,CCT7,IAH1,MBD5,NTMT1,SUMO2,NUP153,H2AX,NCSTN,RANBP1,TP53,TOP3B,RAF1,NUPR1,RBPJ,RAB4A,EZH2,HAPSTR1,FAF1,CDK2AP2,HNRNPK,G3BP1,NUP107,DYNC1I1,H3C1 |
| 2.396e-03 | -6.03 | TAE1 (N-terminal protein methyltransferase) | protein interactions | 852564 | 104 | 43 | 19454 | 5460 |
SF3B4,UBE2I,HOMER3,JAKMIP2,SIAH1,ACTB,GSTA4,PLSCR3,GMDS,RNF40,CFL2,CEP70,FATE1,NFYA,TRIM32,CAP2,LDHB,STAC3,HNRNPC,SSX2IP,REEP6,SPOP,RABAC1,RTN4,MYD88,UGP2,COIL,FTL,PRPS1,GNMT,RNF5,ZBED1,RPIA,MAPK1IP1L,MX1,THAP1,PTS,AGTRAP,SH3GLB1,ZBTB26,SOD2,TFCP2,NME1 |
| 2.397e-03 | -6.03 | RRM | smart domains | SM00360 | 202 | 72 | 9717 | 2575 |
RBM42,HNRNPDL,SRSF2,SRSF1,RBM23,RBFOX3,RBFOX2,BOLL,HNRNPA2B1,SRSF8,G3BP1,SNRNP70,RBMX2,EIF3G,CELF6,RBM34,RBMS2,EIF4B,NONO,SRSF12,HNRNPH3,TIA1,IGF2BP1,EIF4H,HNRNPAB,SRSF10,RBM22,SNRPA,POLDIP3,PPIL4,CIRBP,TRA2B,NCBP2,RBM15B,RALYL,RBM12,PABPC5,RBM41,UHMK1,HNRNPH2,RBM5,HNRNPL,SART3,HNRNPF,TRA2A,HNRNPA1,ALYREF,HNRNPC,RBM3,SF3B6,PABPC1,SNRPB2,RBM38,MYEF2,MATR3,ELAVL2,SYNCRIP,EWSR1,HNRNPA0,PSPC1,RBM7,SRSF7,RBM18,G3BP2,RBM27,SRSF4,CSTF2T,HNRNPD,GRSF1,ELAVL4,SF3B4,ZCRB1 |
| 2.406e-03 | -6.03 | TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | REACTOME pathways | R-HSA-975110 | 12 | 9 | 10285 | 3229 |
TLR9,TLR7,UBE2N,MYD88,IRAK4,IRF7,TRAF6,TLR8,UBE2V1 |
| 2.409e-03 | -6.03 | RAB43 (RAB43, member RAS oncogene family) | protein interactions | 339122 | 45 | 22 | 19454 | 5460 |
LHFPL2,TRAPPC3,TRAPPC10,APEX1,VIRMA,TRAPPC6B,RAB5C,TRAPPC2L,TRAPPC14,TRAPPC4,NBN,TRAPPC1,RAB33B,CRY1,RABAC1,UBL3,RAF1,TOP3B,CFAP36,GDI2,TRAPPC13,HEXIM1 |
| 2.409e-03 | -6.03 | MAP9 (microtubule associated protein 9) | protein interactions | 79884 | 45 | 22 | 19454 | 5460 |
LCA5,EZH1,EP300,PSENEN,ACTB,IL13,H2AJ,NDC80,TP53,EHHADH,LBH,ANAPC15,CSNK2A1,KIF2A,AK2,GNPDA2,PEA15,RPL10A,MAPRE1,CAMSAP2,TRIM36,ANKRD50 |
| 2.409e-03 | -6.03 | NHSL1 (NHS like 1) | protein interactions | 57224 | 45 | 22 | 19454 | 5460 |
TULP3,PPP2R1A,TP53,RAF1,TOP3B,FGFR1,S100B,CTNNB1,YWHAH,YWHAG,NDC80,PPP2R5A,YWHAB,NCK1,YWHAZ,GSK3A,CTNNA1,VIRMA,NCKAP1,EGLN3,PRNP,ACTB |
| 2.409e-03 | -6.03 | Cdc23 (CDC23 cell division cycle 23) | protein interactions | 52563 | 45 | 22 | 19454 | 5460 |
TRIM27,ANAPC2,MAD2L1,CDC20,FZR1,BUB3,GNPTG,ANAPC15,CDC16,PYCR2,PYCR1,CDC26,ANAPC4,CDC23,PDF,ANAPC16,ATP5PF,SKP1,ANAPC11,NEK2,TIMM13,ANAPC13 |
| 2.409e-03 | -6.03 | SLX1B (SLX1 homolog B, structure-specific endonuclease subunit) | protein interactions | 79008 | 45 | 22 | 19454 | 5460 |
PSMA3,FTL,SMN1,PAGR1,PSMA1,PSMA5,HUWE1,PSMA2,PSMB3,FKBP10,PSMB1,S100A8,RAN,PSMA6,PSMB5,TUBA1B,UQCRC2,DUSP10,PSMD6,PSMA4,PSMB2,SLX1A |
| 2.409e-03 | -6.03 | GNB3 (G protein subunit beta 3) | protein interactions | 2784 | 45 | 22 | 19454 | 5460 |
GNG10,GNG3,GNG13,GNAI3,GNAQ,PDCL,NGB,GNG7,EZH2,RGS6,GNGT2,GNG5,GNG11,GNG2,CIDEB,GNB3,GNG12,GNB1,CDC5L,GNAI2,CD47,ZNF511 |
| 2.409e-03 | -6.03 | EPOR (erythropoietin receptor) | protein interactions | 2057 | 45 | 22 | 19454 | 5460 |
NOSIP,KIT,FBXW7,SOCS2,SYK,SOCS3,EPO,CRKL,GAB1,STAT5A,EGLN3,KLK3,SRC,JAK2,PIK3R1,PTPN11,CUL2,GRAP,ELOC,CISH,SHC1,CBL |
| 2.409e-03 | -6.03 | TMEM45B (transmembrane protein 45B) | protein interactions | 120224 | 45 | 22 | 19454 | 5460 |
FAM3C,INSIG2,SEC22A,TMEM60,NSG1,FKBP8,METTL18,TMEM254,TMEM243,DOLK,PLN,CYB561D2,VAMP5,PLPP4,ANKRD46,TMEM97,PLP1,UBE2G2,SMAP2,SYNGR1,TMEM229B,SEC23A |
| 2.410e-03 | -6.03 | hyperplasia | COSMIC cancer mutations | hyperplasia | 52 | 25 | 16828 | 4835 |
PTEN,NTRK3,FGFR1,JAK2,FBXW7,MET,KIT,TP53,SMAD4,IDH1,IL6ST,KRAS,PIK3CA,PTPN11,AKT1,IDH2,GNA11,RB1,CTNNB1,SF3B1,CDC73,GNAQ,MAP2K1,PIK3R1,HRAS |
| 2.414e-03 | -6.03 | APBB1 (amyloid beta precursor protein binding family B member 1) | protein interactions | 322 | 185 | 70 | 19454 | 5460 |
EGLN3,STX6,DHX15,CAV1,DNAJC1,ARF6,PRNP,GJA1,PTPN1,RAB35,RHOG,YWHAH,LAMP3,YWHAG,LAMP2,RBM17,RAB5C,FKBP8,SAR1B,PTGES3,PCGF6,KRAS,PSMA5,RAB3B,HNRNPK,WASL,THRAP3,DHX9,IGF1R,TMT1A,PABPC1,PQBP1,SART3,VPS33A,TFRC,TFCP2,RPN1,RAB4A,WBP11,FASLG,DCAKD,ELMO1,TAMM41,SF3B4,SEC61B,ATXN1L,RCL1,SYP,LAMTOR1,F9,RHOB,PPP1CC,NONO,RAB2A,LMO2,OST4,RAB11A,STX7,CYFIP2,RPL4,SF3B1,THBS3,RAB5A,DERL1,RAB9A,RPA3,DDX46,RPA2,SEC62,SF3A1 |
| 2.415e-03 | -6.03 | regulation of secretion by cell | biological process | GO:1903530 | 551 | 193 | 18204 | 5365 |
NLGN1,IFNG,SDCBP,SDC4,TIAM1,DYNLL1,VPS4A,IL13,RAB8B,NEO1,ADORA3,ADORA1,PPID,SCAMP5,UQCC2,FGFR1,P2RY1,GABBR1,KCNJ11,RAC2,CD200,TLR4,LEP,LRRC8A,PTPN11,FGF23,SLC6A4,C1QTNF1,CHRNB2,SLC38A2,CPLX1,OSM,SNCG,TSPO,SV2B,SLC16A1,OPRK1,PPARG,NDUFAF2,APBB3,TNF,ADIPOQ,VAMP7,RAB33B,CCN3,CRHBP,RHBDD3,KLRC2,RAP1A,ASIC1,SCG5,CXCL12,HFE,STX1A,CDK5,GOLPH3L,SYK,STXBP6,SELENOT,NKX3-1,FCGR2B,S100A10,SPHK2,SYBU,DNAJC1,MAP2K6,VAMP2,SYP,P3H1,GNA11,SRI,NPY5R,CHRM3,CACNB4,TLR2,NLGN2,RAB5A,SLC12A2,CFTR,CD38,CD2AP,GJA1,ADGRE2,C2CD2L,GRM2,ARF6,VAMP3,PICK1,CCR2,F2,FGR,RIMS3,IL12B,PREPL,HCRT,CASK,KCNB1,CCL5,ACVR1C,ACSL4,BGLAP,PPIA,PTGES,GNAO1,ERP29,IL6,ARFIP1,SFRP1,CREB1,RSAD2,CPLX3,REN,HTR2A,IL12A,LILRB1,RASL10B,KCNA2,RAB9A,MIF,OPRM1,PARD6A,SNAP25,VEGFC,HTR1A,ACHE,CHMP2A,MEF2C,FERRY3,EFNA5,LGI3,SNAPIN,UCN,VPS18,FKBP1B,TACR1,RGCC,PLCB1,PCK2,TNFRSF1B,GNAZ,ILDR1,INHA,MIR146A,HADH,SYT4,IL1A,TGFB2,PPFIA2,OSBP,IGF1,RIMS4,ENY2,UCP2,NPVF,JAGN1,OXTR,RALA,RETN,RAB3D,VAMP8,TGFB3,SPP1,IL1B,P2RY4,DPH3,PPP3CA,WNT7A,ADTRP,DRD3,PFKFB2,SMAD4,VPS4B,NR1H2,OR51E2,JAK2,STXBP1,TSG101,SLC4A8,BAD,CRHR1,RAB27A,RAP1B,CRY1,PRKCB,CPLX2,PRKCE,CHGA,HGS,GNAI2,GHRL,CARTPT,RAB3A,CNR1 |
| 2.417e-03 | -6.03 | LRRC57 (leucine rich repeat containing 57) | protein interactions | 255252 | 32 | 17 | 19454 | 5460 |
STX7,KRAS,ARF6,AKAP1,TMT1A,MACIR,HRAS,RHOB,FAS,LAMTOR1,CFTR,LRRC40,XPO1,CSGALNACT2,RAB2A,ATG9A,DPP4 |
| 2.417e-03 | -6.03 | SNRK (SNF related kinase) | protein interactions | 54861 | 32 | 17 | 19454 | 5460 |
MYH2,STUB1,MME,CSNK2B,SLC31A1,VIRMA,TRMT61A,ABHD5,GTF3C4,CSNK2A1,XPO1,JUN,MYH1,CBX3,ARCN1,STK16,STK11 |
| 2.417e-03 | -6.03 | KCNQ5 (potassium voltage-gated channel subfamily Q member 5) | protein interactions | 56479 | 32 | 17 | 19454 | 5460 |
YWHAB,YWHAZ,DISC1,SSR1,YWHAG,LAMP3,YWHAH,KCNQ5,SFN,LAMP2,SRC,DYNLL1,HNRNPL,MTDH,SEC61B,TMT1A,KCNA2 |
| 2.417e-03 | -6.03 | B3GALT4 (beta-1,3-galactosyltransferase 4) | protein interactions | 8705 | 32 | 17 | 19454 | 5460 |
RAB29,METTL18,TMX3,GGT7,PRSS8,SLC39A7,ASIC1,DYNLL1,HSPA5,ABHD12,DAAM1,FAM234A,TUBA1A,CNPY3,TMEM165,HFE,PLAA |
| 2.417e-03 | -6.03 | BLTP1 (bridge-like lipid transfer protein family member 1) | protein interactions | 84162 | 32 | 17 | 19454 | 5460 |
RAC2,SEC61B,RHOU,HRAS,SOD1,VIRMA,HNRNPL,BUB3,RHOH,RHOJ,PRNP,CDC42,RND2,RND3,RHOG,AGR2,RHOB |
| 2.420e-03 | -6.02 | nucleoside phosphate metabolic process | biological process | GO:0006753 | 523 | 184 | 18204 | 5365 |
DLAT,ENO1,HTR2A,ATP5F1A,PNP,NDUFS8,UCK2,UPRT,GPD2,GLYAT,SULT1B1,NDUFB7,PDE7A,NDUFA12,SUCLG2,HACD2,NUDT18,MMUT,STOML2,ACSL4,DNAJC30,FITM2,RAB23,CASK,FMO2,SLC25A1,ALDH1L1,IER3,NDUFB6,GUK1,MFN1,NDUFC2,OGDHL,PRPSAP1,NUDT5,PCK2,DTYMK,MDH1,ATP5PO,AK2,ELOVL7,ENTPD3,DCAKD,DCTPP1,ADCY3,REXO2,ATP6V1A,ADSS2,PC,NDUFS3,ACOT6,NME4,NUDT19,LDHB,OLA1,PGAM1,ABHD14B,FMO1,PDE8A,LDHA,NDUFA1,PFKFB2,FKRP,SULT1A3,PDHB,ATP5MG,KARS1,UCP2,UQCC3,RPIA,PDE1A,ATP5PD,NUDT2,PRPS1,NPR2,ATP5F1B,ATP5PF,TECR,DLG1,MVD,RPE,ATP1A2,NDUFA2,ATP1B1,TP53I3,DNPH1,ACACA,IDH1,BAD,DCK,ADCY2,ATP5MC1,HSPA8,ACSS2,NT5C3A,NDUFAB1,NME1,NDUFB10,MTHFD2L,IDH2,MPP1,ENO2,PDE4B,ATP5MC3,COX11,GNAI3,ADK,NDUFS2,GMPS,IDO1,NUDT4,ATP5PB,NMRK1,ELOVL3,CNP,FHIT,DLST,NDUFV2,PGM1,NDUFS6,SDHC,PDE9A,RAN,NQO1,NUDT7,NDUFB8,PAPSS2,AK5,LIPA,PGK1,ELOVL4,SLC52A3,RRM1,HACD1,NUDT16,GAPDH,NDUFB4,HINT1,FAR2,CMPK1,SMUG1,ATP5F1E,AK3,SAMHD1,HMGCS1,EPHA2,PPAT,GTPBP1,NDUFA5,NME2,ATP5MK,PPT1,UCKL1,SARM1,SHMT1,NT5C2,GPAM,ENTPD4,G6PD,PDHA1,TPST1,NUDT12,CD38,UMPS,ACOT8,ACAT1,BPGM,SDHB,PTHLH,NUDT9,PDE2A,DCTD,ELOVL6,UCK1,CLPX,NPPC,OGG1,ELOVL1,NUDT3,TYMS,GUCY1B1,CACNB4,ATP5F1D,NDUFB5 |
| 2.420e-03 | -6.02 | TMEM170A (transmembrane protein 170A) | protein interactions | 124491 | 13 | 9 | 19454 | 5460 |
GCC1,ARL6IP5,FAM241B,REEP6,RIGI,SRC,CDIPT,FAM241A,ADGRG1 |
| 2.420e-03 | -6.02 | GTF2IRD2B (GTF2I repeat domain containing 2B) | protein interactions | 389524 | 13 | 9 | 19454 | 5460 |
GTF2IRD1,GTF2I,TRIM54,APEX1,ACVR1C,HEXIM1,POLR2B,MEPCE,ZMYM2 |
| 2.420e-03 | -6.02 | IDI2 (isopentenyl-diphosphate delta isomerase 2) | protein interactions | 91734 | 13 | 9 | 19454 | 5460 |
BCL6,SSBP3,RABL2B,LMO4,LDB1,SSBP4,TRIM27,FAM76B,SSBP2 |
| 2.420e-03 | -6.02 | AKR1B15 (aldo-keto reductase family 1 member B15) | protein interactions | 441282 | 13 | 9 | 19454 | 5460 |
FBXW7,TRAF2,AKR1B1,HINT1,HSD17B10,GLO1,SOD1,ENO2,ENO1 |
| 2.420e-03 | -6.02 | TK2 (thymidine kinase 2) | protein interactions | 7084 | 13 | 9 | 19454 | 5460 |
KRAS,CTNNBIP1,NUBP2,DKK1,ANAPC15,MRPL9,DDX39A,LIG3,GSTK1 |
| 2.420e-03 | -6.02 | CD40LG (CD40 ligand) | protein interactions | 959 | 13 | 9 | 19454 | 5460 |
CD40,TP53,TRAF2,BIRC2,RNF128,CRYAB,CD40LG,TRAF1,RIGI |
| 2.421e-03 | -6.02 | PKP2 (plakophilin 2) | protein interactions | 5318 | 222 | 82 | 19454 | 5460 |
LAMTOR1,RC3H2,DCAF4,RHOB,YWHAZ,MYO6,NCKIPSD,NTRK3,CCHCR1,ILK,CDKL2,RAB2A,MYC,SFN,CUL3,RAB11A,NTAQ1,BTF3,DEPDC1B,MATR3,MAGOHB,RPGRIP1L,RHOJ,VIRMA,MAD2L2,CTNNA1,RPA2,JUP,CTBP1,GTF2IRD1,FGFR1,ATG16L1,CDC42,CCL3,TACR3,STX7,RPA3,PML,HSPB2,TACR1,AKAP1,RAB9A,DROSHA,SNRNP70,SMAD9,PEX3,YWHAB,ARMC8,LAMP2,WWP2,YWHAH,HSPB8,LAMP3,YWHAG,CTNNB1,PCED1A,ARF6,RHOH,DIRAS3,LMAN1,EPHB6,EGLN3,CAV1,RAB35,GTF2B,RBM5,GJA1,EED,MINDY3,PNMA2,CASK,RAF1,TOP3B,LPAR6,EXOSC8,FGD2,G3BP1,EPHA4,KRAS,FLOT1,NTRK2,FHL3 |
| 2.426e-03 | -6.02 | BTG2 (BTG anti-proliferation factor 2) | protein interactions | 7832 | 27 | 15 | 19454 | 5460 |
PRKCA,SMAD9,CDK1,FBXL3,FBXW11,CNOT8,SMAD1,CCNB1,TRIM6,CNOT6L,SKP1,RIGI,CNOT7,HNRNPL,PICK1 |
| 2.426e-03 | -6.02 | ARHGAP20 (Rho GTPase activating protein 20) | protein interactions | 57569 | 27 | 15 | 19454 | 5460 |
CDC42,SUB1,MRPL11,TP53,SF3A1,SNRNP70,CSTA,SEC61B,WDR6,MRPS7,DEK,ESR2,VIRMA,CHCHD3,PLG |
| 2.426e-03 | -6.02 | LRRC32 (leucine rich repeat containing 32) | protein interactions | 2615 | 27 | 15 | 19454 | 5460 |
SLC16A10,CNPY3,TMEM11,SMPD2,RPN1,PPM1B,ITGB8,LEMD3,CBFB,SLC39A10,FMOD,DCP2,KRAS,DAD1,HSPA5 |
| 2.426e-03 | -6.02 | RIC1 (RIC1 homolog, RAB6A GEF complex partner 1) | protein interactions | 57589 | 27 | 15 | 19454 | 5460 |
STX6,CAV1,VIRMA,HNRNPL,KRAS,RAB1B,FBXO22,SYNGR1,MAP1LC3A,RGP1,RAB1A,MAP1LC3B,PTAR1,TOP3B,BET1 |
| 2.426e-03 | -6.02 | ST3GAL1 (ST3 beta-galactoside alpha-2,3-sialyltransferase 1) | protein interactions | 6482 | 27 | 15 | 19454 | 5460 |
ATP1A3,TRAF6,TOP3B,PSEN1,ITGAV,RMND1,APEX1,VIRMA,HNRNPL,ERLEC1,ANKRD46,SLC39A10,SLC30A7,STARD3NL,GSTA1 |
| 2.426e-03 | -6.02 | GIMAP8 (GTPase, IMAP family member 8) | protein interactions | 155038 | 27 | 15 | 19454 | 5460 |
AK2,NUDT19,SRP72,FXN,GABARAPL2,MTPN,AK3,TXNDC12,TXN,PAK6,TCOF1,PTRHD1,FAHD1,COA4,SRP54 |
| 2.426e-03 | -6.02 | CAB39L (calcium binding protein 39 like) | protein interactions | 81617 | 27 | 15 | 19454 | 5460 |
FAS,CHMP1A,STK11,MX1,BTF3L4,METTL15,CFTR,MAGOHB,HNRNPL,SCML2,LIN7C,BCL7B,BCKDK,RAP1B,CAB39 |
| 2.426e-03 | -6.02 | CRTC1 (CREB regulated transcription coactivator 1) | protein interactions | 23373 | 27 | 15 | 19454 | 5460 |
KCTD3,KDM1A,SRPK2,TFG,CREB1,EP300,PHF21A,BICD2,YWHAZ,YWHAB,TBK1,CREBBP,YWHAH,XPO1,YWHAG |
| 2.426e-03 | -6.02 | SLC22A1 (solute carrier family 22 member 1) | protein interactions | 6580 | 27 | 15 | 19454 | 5460 |
TMEM147,CD63,SLC25A11,LAPTM4A,CYSTM1,CCL2,CERS2,CAPN1,TMEM179B,FIS1,PDZK1IP1,GHITM,CD9,SPP1,VAPB |
| 2.426e-03 | -6.02 | DNAH14 (dynein axonemal heavy chain 14) | protein interactions | 127602 | 27 | 15 | 19454 | 5460 |
KCTD12,CTLA4,RELL2,FBXO7,IKZF5,MICB,PDIA3,CUL3,CETN2,FTL,APEX1,SLC31A1,HNRNPL,LHFPL2,TNFRSF1B |
| 2.427e-03 | -6.02 | FGFR3 (fibroblast growth factor receptor 3) | protein interactions | 2261 | 313 | 111 | 19454 | 5460 |
RAD21,USP30,EPHA4,MYO1B,FHL3,GPSM3,TMEM87A,FGF3,ATF3,HGS,STIM1,NDUFS6,NUDCD3,CBLN4,PI15,CACYBP,HSP90AB1,DNAJB9,EIF2S1,HNRNPL,KRT8,RPL8,DNM2,MRTO4,SDC4,AHSA1,MRPS26,YWHAB,FGF1,BAZ1B,PIK3R1,CFC1,POLA2,UNC45A,MRPS7,HSPA8,ARRDC3,HADHA,PIH1D1,VAPB,SDC2,TIMM13,ETF1,RAB6A,TMEM231,TIMM10,PAFAH1B1,FGF17,TNPO3,STAT1,FGF7,DLST,HSP90AA1,SERPINH1,NSA2,CTSK,MRPS25,MYO6,GGH,VEZT,PYCR1,ARF4,TMEM33,DNAAF10,TTC4,SRPRB,MRPS18B,STX18,CTLA4,SOCS3,TIMM8A,FGF23,MRPL47,KLK3,CDK6,STT3A,MRPS9,AIP,ELSPBP1,SRPRA,UBE2N,KARS1,GPIHBP1,SQSTM1,MAVS,SNX11,BANF1,HEXIM1,CDK1,MRPS34,ZNF326,FGFR1,MRPL10,CNP,TECR,SRPK2,SEC63,SEC61A1,DNASE1L1,EIF2S2,MACROH2A1,STUB1,MRPL53,EPHA2,AP2A1,XPOT,SDF2L1,GORASP2,SMARCA5,PYCR2,PTPN11 |
| 2.430e-03 | -6.02 | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | REACTOME pathways | R-HSA-2404192 | 299 | 117 | 10285 | 3229 |
FGF10,DUSP9,SRC,PSMD10,FRS3,RAF1,WDR83,UBA52,FGF22,KRAS,MAP2K1,RAP1B,PPP2R5A,FGF1,DUSP6,YWHAB,PIK3R2,IL2RG,PSMB3,PEBP1,TLR9,EIF4E,PPP2R5E,SPTAN1,PSMA5,FGF23,PAQR3,STRADB,MET,DUSP1,PRKAB1,SEM1,PSMB4,SHC1,RASGRP3,SPRED1,PSMD4,PHB1,IL3,RPS27A,PSMA1,PSMC3,PRKAG1,PSMC1,CUL3,VWF,CAMK2G,LAMTOR3,IL2RB,FGF16,PSMA6,PEA15,AKT1,PIK3CA,PSMB2,PSMD1,IL5,GAB1,HRAS,PPP2CB,KIT,LAMTOR2,FGF17,PSMD7,ANGPT1,PSME1,PPP5C,SPTBN1,PPP2R1A,UBB,STK11,IGF1,PTPN11,PSMD14,PSMC4,PSMA3,PSMB5,PSMB1,PIK3R1,PSMB7,JAK2,PSMD3,BRAP,CSK,RHEB,DLG4,PSMB6,PSMA2,PSMB10,PSMC5,IL2,FGFR1,PSMB11,PSMA4,IL2RA,SPRED2,PSMB9,HBEGF,PSMD6,PSME2,FGF3,NEFL,DUSP10,IGF1R,RRAGB,MAP3K11,PSMD12,FGF7,JAK1,LAMTOR1,CSF2,CAB39,RAP1A,RRAGA,SHC3,EIF4B,AKT2 |
| 2.433e-03 | -6.02 | Regulation of IFNG signaling | REACTOME pathways | R-HSA-877312 | 14 | 10 | 10285 | 3229 |
SOCS3,PTPN11,PIAS1,JAK2,IFNG,STAT1,IFNGR1,SUMO1,JAK1,PTPN1 |
| 2.436e-03 | -6.02 | negative regulation of protein serine/threonine kinase activity | biological process | GO:0071901 | 94 | 41 | 18204 | 5365 |
CDKN1B,MIR20A,PTPN22,PKIG,HEXIM2,IL1B,RGS2,PTPN1,AKT1,INPP5K,MIR711,GADD45A,PPARG,MIR218-1,SPRY1,HEXIM1,PAQR3,STK38,DUSP10,PKIA,SLC8A1,PYCARD,ADIPOQ,PTEN,CDKN1A,LRP6,MACROH2A1,MIR24-1,PKIB,HYAL2,GSTP1,CDK5RAP3,PDCD4,TESK1,RB1,DUSP1,CAV3,MIR15A,DUSP19,DEFB114,MIR34A |
| 2.437e-03 | -6.02 | RBM12 (RNA binding motif protein 12) | protein interactions | 10137 | 107 | 44 | 19454 | 5460 |
SATB1,KRAS,RIGI,RNF20,MRPS11,FBXO11,TBC1D4,CENPM,METTL26,GTF2E2,RPL35A,NUP35,FUBP3,OR4Q3,SDHAF2,MTAP,IGBP1,GMPPB,MOV10,HNRNPA1,TMA16,PML,RPA3,SLU7,RPA2,GSTO2,TIMMDC1,PCK2,RBFOX2,SNRNP27,PRMT2,SNX3,CCNF,OPTN,NIPA2,CYP1A1,ADK,CDKN2D,CABCOCO1,SNRPB,AR,RNF40,BRAP,PSMD1 |
| 2.438e-03 | -6.02 | PRPS1 (phosphoribosyl pyrophosphate synthetase 1) | protein interactions | 5631 | 182 | 69 | 19454 | 5460 |
GORASP2,BRMS1,MYC,UBE2H,THTPA,DNAJB6,SPOP,DCAF16,IVNS1ABP,GTF2F1,CCNF,SMURF1,SH3BGRL,UBB,GMDS,PPAT,CDC42,ELP3,ELK4,ATG16L1,ACSS2,PRKCA,PIH1D1,CAV2,SHOC2,RPA2,NMRAL1,RAB5A,EP300,PEBP1,BAP1,RHOU,RPA3,HSPA5,CXXC1,UFL1,DDRGK1,PRPF19,FAM174A,EMC4,ARMC8,FGR,CRBN,SNRNP70,AGR2,NCK1,LHFPL4,FBXO31,PHB1,WIF1,CAV1,ASB11,CARTPT,DUSP1,MSX2,SPG21,HSDL2,RAF1,DTWD2,RNF8,CHMP4C,HAPSTR1,EWSR1,PRPSAP1,RPAP3,NOSIP,PFDN1,PRPS1,FARSA |
| 2.438e-03 | -6.02 | SLC12A2 (solute carrier family 12 member 2) | protein interactions | 6558 | 182 | 69 | 19454 | 5460 |
DNAJC25,CCDC47,RND3,RPN1,RAB4A,EFNB1,COX8A,CYP2C9,TMT1A,FLOT1,KRAS,EPHA4,RAB3B,YWHAH,LAMP3,LAMP2,RAB5C,RHOG,AGR2,HSD17B11,GJA1,RAC2,HRAS,RAB35,PTPN1,SRSF1,STX6,LMAN1,DIRAS3,CAV1,ARF6,DNAJC1,RHOH,SEC62,CDC42,OTULINL,RND2,ST7,BET1,OXSR1,SLC12A2,GPR35,SSR1,RAB9A,DERL1,PMAIP1,RAB5A,RHOU,STX7,PXMP2,DNAJC5,RAB2A,SEC13,RAB11A,ILK,CDKN2AIP,LAMTOR1,RHOB,LGALS8,PTEN,SEC61B,LMBR1L,GNG12,APLNR,SEC63,ESR2,VIRMA,RHOJ,LGALS3 |
| 2.445e-03 | -6.01 | OTUD6B (OTU deubiquitinase 6B) | protein interactions | 51633 | 81 | 35 | 19454 | 5460 |
CRMP1,CASC3,RPL10A,FAS,H1-10,DNAJC10,RPF2,RPL6,RPL7A,SMURF1,RPL19,APEX1,RPL35A,HDDC2,RPL7,AP2M1,FAU,SULT1A3,SWAP70,RPL32,METAP2,RPLP0,EIF4B,RPS11,RPL18,RPL29,SPC24,GBE1,EIF4E,NEDD8,RPS15,RPL4,STAU1,MTDH,GALC |
| 2.445e-03 | -6.01 | TBCK (TBC1 domain containing kinase) | protein interactions | 93627 | 81 | 35 | 19454 | 5460 |
THRAP3,FLOT1,CAPZA1,VTA1,SNRPA,HADHA,MYO1B,FERRY3,NEFL,LMNA,CBX3,GNAI3,TP53,SPTBN1,CD59,ACTN4,RPL7L1,SPTAN1,TMOD3,INA,HNRNPL,GNAI2,SRC,GNB1,CHCHD3,DKC1,SRSF10,CBX5,COX4I1,H2AZ1,CORO1C,ADD1,PMPCA,CFL2,CSNK2A1 |
| 2.445e-03 | -6.01 | GRIP1 (glutamate receptor interacting protein 1) | protein interactions | 23426 | 81 | 35 | 19454 | 5460 |
PHF1,H3C1,B9D2,FXR2,FGF12,PICK1,EFNB1,EP300,IRF3,GRIA2,PPARG,GRIK1,GRM2,TUBA1A,FNTB,VDR,GPR37,EFNA5,UBE2I,TES,GRIA1,SMAD3,WDR6,DCAF11,YWHAB,YWHAZ,YWHAH,DEPDC1B,YWHAG,CTNNB1,AR,AGAP2,CREBBP,CUL3,SFN |
| 2.445e-03 | -6.01 | DMWD (DM1 locus, WD repeat containing) | protein interactions | 1762 | 81 | 35 | 19454 | 5460 |
HBB,CAPN2,NDUFA5,GNAZ,TOP3B,ZNF581,NDUFS2,SRM,FTSJ1,IDH3A,HSPA8,P4HA2,YWHAZ,FERD3L,OAT,HSPB1,TSNAX,YWHAB,CUL3,YWHAH,YWHAG,XPO1,CAV3,F7,FEM1B,CTSB,CCR2,SUCLG2,VIRMA,WDR6,S100A8,GNAO1,ARHGAP25,ALB,USP46 |
| 2.447e-03 | -6.01 | NAD(P)-binding Rossmann-like Domain | gene3d domains | 3.40.50.720 | 167 | 65 | 14470 | 4137 |
ADH1A,HSD11B1,LDHB,ADH1B,G6PD,UGDH,CRYL1,KDSR,RDH10,AHCYL1,LDHA,DHRS4,SORD,CD38,RDH12,HSD17B1,EHHADH,NSDHL,HSD17B10,GFOD1,CRYM,HSDL1,DHRS11,MTHFD2L,GALE,HADH,NMRAL1,PYCR1,DHRS7B,DHRS7,BLVRA,HSD17B6,GFUS,HSD17B11,HSDL2,HSD17B8,SDR16C5,HADHA,RDH11,GAPDH,ATG7,DHRS13,GFOD2,NAE1,MECR,KCNMA1,DHRS3,GMDS,UBA3,MDH1,PYCR2,TP53I3,DHRS1,CBR4,ISYNA1,MAT2B,CRYZ,SPR,CBR3,DECR2,FAR2,SDR42E1,CTBP1,HSD17B3,LDHAL6B |
| 2.450e-03 | -6.01 | regulation of response to endoplasmic reticulum stress | biological process | GO:1905897 | 83 | 37 | 18204 | 5365 |
NR1H2,SERINC3,BOK,SVIP,BCL2L1,DDRGK1,NFE2L2,USP14,CAV1,COPS5,NUPR1,NCK1,ERP29,BAX,SYVN1,PMAIP1,BAK1,TXNDC12,PTPN1,TMBIM6,CLU,TMEM33,XBP1,USP13,PIK3R1,STUB1,HSPA5,BFAR,CREB3,LPCAT3,DNAJB9,SGTA,SELENOS,UFL1,FCGR2B,AQP11,AGR2 |
| 2.450e-03 | -6.01 | positive regulation of B cell activation | biological process | GO:0050871 | 83 | 37 | 18204 | 5365 |
CD40,IL4,BCL6,MIF,XBP1,SASH3,CD38,SYK,TLR9,TNFSF13,CD81,TLR4,PELI1,IL2,STAT6,TIRAP,IL10,MMP14,CDKN1A,SLC39A10,HMCES,TICAM1,MAD2L2,IL5,CHRNB2,IL2RG,EXOSC3,IL13,TFRC,MEF2C,BAD,IL7,IL21,CD28,SHLD1,IL6,KMT5B |
| 2.450e-03 | -6.01 | regulation of amine transport | biological process | GO:0051952 | 83 | 37 | 18204 | 5365 |
SLC43A2,STXBP1,TNF,KCNB1,DRD1,CHGA,SLC38A2,PRKCB,SLC38A1,NPY5R,CHRNB2,OXTR,CLTRN,RAB3B,SLC6A1,KCNA2,SNCG,GABBR1,P2RY1,RGS2,SLC12A2,STX1A,SLC38A3,ADORA1,ADORA3,HTR2A,CXCL12,SYT4,OPRK1,GRM2,CNR1,LEP,ARL6IP5,DRD3,PSEN1,CARTPT,ATP1A2 |
| 2.456e-03 | -6.01 | SYNAPTOBREVIN | prosite domains | PS00417 | 7 | 6 | 12186 | 3388 |
VAMP1,VAMP2,VAMP3,VAMP5,VAMP7,VAMP8 |
| 2.457e-03 | -6.01 | ovary-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-small_cell_carcinoma | 125 | 51 | 16828 | 4835 |
PTPN11,NOTCH2,RB1,GNA11,CTNNB1,SRSF2,SMARCB1,MYD88,DICER1,PIK3CA,SUFU,SF3B1,CDC73,JAK2,CDKN2C,PPP2R1A,KIT,BRCA1,PTEN,NTRK3,CD79B,TERT,IDH1,CBL,FBXO11,SMAD4,AKT1,IDH2,TSHR,EZH2,EP300,JAK1,PIK3R1,MSH6,TNFRSF14,HRAS,RUNX1,XPO1,NFE2L2,STK11,GNAQ,MAP2K1,NF2,FBXW7,MET,TP53,FGFR1,CREBBP,KRAS,TNFAIP3,BAP1 |
| 2.460e-03 | -6.01 | C7orf50 (chromosome 7 open reading frame 50) | protein interactions | 84310 | 179 | 68 | 19454 | 5460 |
THAP1,AURKAIP1,SOX2,HBP1,CHMP4C,RPL3,MAP1B,RPL17,FBXO25,RPL28,H3C1,DDRGK1,COPS5,WWP2,IFI16,GRSF1,LHX2,SNRNP70,RPL32,PHB1,SRSF1,RPL8,KLF9,ZBTB2,SURF6,CGAS,PRNP,LYAR,CAND1,FZR1,HNRNPL,KLF12,BET1,PIH1D1,RPLP0,PAX9,RPA2,RNF113A,MTDH,RAB9A,RPA3,G3BP2,RPL4,STAU1,FBXW7,RPS15,NPM3,DGCR8,CCDC85B,ZNF668,THAP7,RPL7A,RAB11A,MYC,UBE2H,MAPRE1,H1-1,SEC61B,RPL37A,PRKRA,FGFBP1,SRPK2,RPL19,RPL10,ESR2,PSMB6,RPL13A,RPL35 |
| 2.463e-03 | -6.01 | tissue remodeling | biological process | GO:0048771 | 108 | 46 | 18204 | 5365 |
MITF,BAX,RAB3D,CTNNB1,FGF10,DBH,CTSK,BAK1,NPR2,VDR,LGR4,NOTCH2,MDM2,IL1A,SNX10,RBPJ,MMP14,PLG,FKRP,SEMA3C,ADRB2,EXT1,RAC2,EPHA2,SRC,IL23A,BMPR2,FOSL2,NFKB1,MEF2C,TIMP1,IL7,NCDN,NPPC,CAV1,ACP5,EDNRA,LIPA,FOXC2,CCR2,CYP1A1,PTN,CAPN1,GJA1,TRAF6,NDP |
| 2.473e-03 | -6.00 | L3MBTL1 (L3MBTL histone methyl-lysine binding protein 1) | protein interactions | 26013 | 110 | 45 | 19454 | 5460 |
AKAP8L,KPNA1,PSMD7,PSMD3,SPPL3,NOP58,PSMB1,RB1,YBEY,PSMB5,PSMB4,ETV6,PSMC3,CBX3,TP53,RIGI,MCM6,PSMA5,PCNA,SETD7,DNAJB6,PSMD14,MCM3,RPS29,MCM4,MLF2,MYC,PSMB2,CBX5,PSMB6,PSMD6,DYNLL1,PSMC5,PELO,SSR1,PSMB7,PSMB3,PSMC4,H1-5,PSMC1,FXR2,RPS15,PSMA3,ATP5MK,ZKSCAN1 |
| 2.473e-03 | -6.00 | WDR74 (WD repeat domain 74) | protein interactions | 54663 | 110 | 45 | 19454 | 5460 |
HDAC11,MAK16,RPSA,CCT5,BUD23,RAF1,RPL17,RPL28,KRAS,RPL3,RBM3,XPO1,IFI16,CCT7,PRNP,LYAR,RCHY1,EEF1AKMT3,SRP14,RPLP0,NUDT3,ATG16L1,RGS2,ZC3H15,RPL4,STAU1,NPM3,DGCR8,DDX39B,DNAJB6,RIT1,H1-1,CCT2,RPL7A,MYC,RPL19,RPF1,RPL13A,RPL35,FBXO22,FGFBP1,PRKRA,CIB2,DLG4,CCNF |
| 2.473e-03 | -6.00 | MTF2 (metal response element binding transcription factor 2) | protein interactions | 22823 | 110 | 45 | 19454 | 5460 |
CREB1,ARF1,ZNF330,EZH1,B4GALT3,RBBP4,CSK,SMARCA5,RAB2A,CDKN2D,PRMT6,PIK3R3,SLC30A5,SLC39A9,KDM1A,NUCKS1,MBD3,FUT8,UBE2M,SIN3A,SMAD3,EED,MYBL2,LDLR,GATAD1,TMED9,SHPRH,BRMS1L,POLE3,ZBTB2,HSP90AB1,HMGA1,SUV39H1,EPOP,HNRNPD,RAB1A,SLC39A3,RBBP7,PHF1,MTA3,SAP30,KIF2A,EZH2,TRAPPC13,MTA2 |
| 2.473e-03 | -6.00 | MARCHF4 (membrane associated ring-CH-type finger 4) | protein interactions | 57574 | 110 | 45 | 19454 | 5460 |
RETSAT,ZMPSTE24,UBE2H,PIGA,SMPD2,SNX14,SDF2L1,LRP12,STUB1,FERMT2,CTSB,ST7,BET1,EPHX1,LRP10,ABCB9,BMPR1A,HSPA5,TMBIM6,YWHAH,DHRS7,ATG9A,BTN2A2,NUS1,C2CD2L,UBE2D1,CD4,TYMS,DIPK1A,LGR4,CYB5R1,NCSTN,ABHD6,PREB,ADCY3,TMEM39A,DHRS3,RAB6B,NRN1,TMEM94,TRAFD1,BAG2,TMEM268,TMEM33,ERLEC1 |
| 2.481e-03 | -6.00 | ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit) | protein interactions | 479 | 176 | 67 | 19454 | 5460 |
GRPR,SLC15A1,SLC37A4,TACR3,MME,VIPR1,TACR1,CTDSP1,TIMM23,CSNK1A1L,HSD17B6,SLC25A3,NPY,HCST,FAXC,SEC62,SPCS1,CEP41,LYZL6,EFNA5,ITM2A,CLRN2,APLNR,S1PR4,IL2RA,RETREG3,TNFRSF9,CD226,ATP1B3,TYROBP,FIS1,GPR17,ST3GAL1,SRPRB,RNF115,HS2ST1,PDE2A,NDUFA4,MRFAP1L1,PRND,LRRN4CL,KLRC2,ADORA3,PTGFR,PLD3,CYB5B,GNAI3,NUDT16,CCR1,MGARP,CTDSP2,AGK,CX3CL1,OPRL1,FEZ1,NAA30,SPINT2,OR10G2,FXYD6,AGPAT1,SMDT1,UPK1A,FAM174A,TSPAN10,ATP1B1,PPIB,CCR6 |
| 2.492e-03 | -5.99 | eosinophil chemotaxis | biological process | GO:0048245 | 26 | 15 | 18204 | 5365 |
CCL18,CCL11,CCL8,CCL4L1,CCL24,LGALS3,CCL2,CCL3,CCL5,SCG2,CCL25,CX3CL1,CCL1,CCL23,XCL1 |
| 2.492e-03 | -5.99 | negative regulation of neural precursor cell proliferation | biological process | GO:2000178 | 26 | 15 | 18204 | 5365 |
ILK,PTN,PROX1,SHOC2,CEND1,SPINT2,BTG2,NR2E1,LIMS2,PAX6,MIR137,SLC6A4,PDE9A,CTNNA1,TP53 |
| 2.504e-03 | -5.99 | TRMT1 (tRNA methyltransferase 1) | protein interactions | 55621 | 113 | 46 | 19454 | 5460 |
HDAC3,P4HA2,HSPA8,EP300,RPA3,EXD2,XRCC5,RTF2,RPA2,JUP,CFTR,APEX1,TCEAL1,STAT1,GANAB,AP2M1,CCNF,H1-1,UBE2H,DNAJB6,SAMHD1,NTAQ1,MYC,CAP2,CUL3,CHCHD2,CHDH,MRFAP1,COX8A,HSPD1,NDUFA12,EZH2,PDHA1,NDUFS6,TOP3B,GBE1,IAH1,TRMT61A,WIF1,YBEY,LDLR,SSBP1,FBXO32,ATG7,CLPX,KARS1 |
| 2.504e-03 | -5.99 | SLC39A6 (solute carrier family 39 member 6) | protein interactions | 25800 | 113 | 46 | 19454 | 5460 |
RETREG3,TNFRSF9,S1PR4,GNAI2,LYPD6,RHOJ,DNAJC5,RAB11A,RAB2A,BRCA1,RHOB,SDF2L1,LAMTOR1,RAB9A,RHOU,STX7,GLRA2,TMEM106A,RND2,SEC62,CDC42,GPR35,SPINT2,RAC2,GJA1,HRAS,RAB35,CAV1,LMAN1,DIRAS3,RHOH,ARF6,P2RY10,LAMP3,RAB5C,LAMP2,SPP1,RHOG,LPAR2,SLC6A8,KRAS,CLEC2B,COMTD1,RND3,RAB4A,TMEM31 |
| 2.513e-03 | -5.99 | NAD(P)-bd_dom_sf | interpro domains | IPR036291 | 152 | 61 | 18521 | 5414 |
GALE,LDHB,GAPDH,DHRS3,DHRS7B,DHRS4,ISYNA1,HADHA,HSD17B8,CRYZ,ADH1B,KDSR,MDH1,LDHA,HSD17B6,RDH10,CRYL1,GFOD2,RDH11,GMDS,CBR4,RDH12,HSD11B1,MECR,UGDH,MTHFD2L,HSD17B3,LDHAL6B,CBR3,SORD,FAR2,DHRS13,HADH,PYCR1,HSD17B10,NMRAL1,DECR2,GFOD1,SDR16C5,MAT2B,G6PD,ADH1A,KCNMA1,PYCR2,HSDL2,SPR,AHCYL1,NSDHL,GFUS,DHRS11,CRYM,HSDL1,HSD17B11,EHHADH,DHRS7,HSD17B1,DHRS1,CTBP1,BLVRA,TP53I3,SDR42E1 |
| 2.514e-03 | -5.99 | genital_tract-extragonadal-germ_cell_tumour | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour | 29 | 16 | 16828 | 4835 |
FBXW7,IDH2,PTPN11,JAK2,TP53,KIT,EZH2,MYD88,PTEN,CBL,IDH1,KRAS,HRAS,XPO1,SF3B1,RUNX1 |
| 2.514e-03 | -5.99 | autonomic_ganglia-adrenal_gland-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-adrenal_gland-neuroblastoma | 29 | 16 | 16828 | 4835 |
PIK3CA,PTEN,CTNNB1,MET,KIT,AKT1,PTPN11,JAK2,IDH2,GNAQ,MAP2K1,EWSR1,KRAS,HRAS,IDH1,PIK3R1 |
| 2.514e-03 | -5.99 | Hodgkin_lymphoma | COSMIC cancer mutations | Hodgkin_lymphoma | 29 | 16 | 16828 | 4835 |
IDH2,CDKN2C,ETV6,JAK2,TP53,EZH2,MYD88,PTEN,PIK3CA,IDH1,PIK3R1,KRAS,HRAS,SF3B1,TNFAIP3,SSBP2 |
| 2.514e-03 | -5.99 | skin-malignant_melanoma-nodular | COSMIC cancer mutations | skin-malignant_melanoma-nodular | 29 | 16 | 16828 | 4835 |
FGFR1,TERT,PIK3CA,PTEN,MET,KIT,CTNNB1,TP53,JAK2,AKT1,IDH2,GNAQ,SF3B1,HRAS,KRAS,IDH1 |
| 2.520e-03 | -5.98 | GPRC5A (G protein-coupled receptor class C group 5 member A) | protein interactions | 9052 | 67 | 30 | 19454 | 5460 |
HRAS,RAC2,GTF2F2,CYB5A,RHOH,RHOJ,ESR2,ATP6AP2,LAMP2,RAB5C,RAB11A,LAMP3,HDAC6,GAPDH,LAMTOR1,RHOB,PSMD14,HSPA8,RAB9A,KRAS,TRIM37,STX7,RAF1,ATG16L1,MPV17,CFTR,ACTR2,WWP1,NUPR1,SLC25A3 |
| 2.520e-03 | -5.98 | ACADSB (acyl-CoA dehydrogenase short/branched chain) | protein interactions | 36 | 67 | 30 | 19454 | 5460 |
PDHA1,RAF1,LYPLA1,DDX39A,FAF2,ACTR1A,YTHDF1,KRAS,HSCB,SAR1B,IMMP2L,BMPR1A,HSPD1,COX8A,SCPEP1,DRG2,SMAD4,SPOP,DRG1,KDSR,RPGRIP1L,TXNDC12,PARL,EGLN3,PHB1,THOC2,CCNF,GATD3,ATP6V1A,SMU1 |
| 2.520e-03 | -5.98 | KIF2C (kinesin family member 2C) | protein interactions | 11004 | 170 | 65 | 19454 | 5460 |
GTF2F1,RMDN3,RBMX2,CSNK2B,TNFRSF1B,CCNF,DUSP3,ESR2,VIRMA,BCCIP,PRRC2A,BMP1,FBXO22,ZNF668,TYW3,NTAQ1,CUL3,MYC,HSPA14,MAPRE1,ANAPC4,BRCA1,HSPA8,DVL2,RPA3,SMC4,SGF29,SNRNP27,TANK,TRIM36,RPA2,RPL9,CDC5L,STK3,MYL12A,EGLN3,RPL7,SUMO2,SPPL3,ACTR3B,STK4,INSYN1,YWHAG,YWHAH,WWP2,KXD1,MOV10,MAP4,HAX1,TRAF6,MED21,SEMG2,FBXO11,LSM14A,MRPL52,MRFAP1L1,SAR1B,UBE2A,SGMS2,KRAS,PSMA5,H3C1,KIF2A,RBPJ,RELL2 |
| 2.526e-03 | -5.98 | RPS6KA3 (ribosomal protein S6 kinase A3) | protein interactions | 6197 | 213 | 79 | 19454 | 5460 |
NFKBIA,BAD,CREB1,CCNF,SFXN2,AP2M1,CSNK2B,SF3B4,DNASE1L1,RHOJ,RBBP4,SRC,RABIF,CREBBP,AKT3,AKT1,FBXO7,NTAQ1,RPS6KA4,STK11,HSP90AA1,PEA15,RPA3,HSPA8,UBE2D3,HSPA5,KDELR2,FGFR1,PICALM,CTBP1,H2BC11,RPA2,EEF1AKMT3,DFFA,SPRED2,SUMO2,CCAR2,SPPL3,HSP90AB1,TMPO,MDM2,GRSF1,HMGA1,UBXN6,HNRNPA1,YWHAG,CSNK2A1,COPS5,YWHAH,NME2,H2BC17,YWHAB,AGPAT1,HSPB1,ATP5PF,HNRNPA2B1,AKT2,H2AC25,TRIM11,BAG2,ABCE1,ROCK2,FOXN2,CSE1L,KRAS,H3C1,H2AC6,STRADB,PRPS1,CTNND1,TP53,HTR2A,RAF1,H2AX,TRAF2,H1-3,NHERF1,EZH2,GTPBP1 |
| 2.531e-03 | -5.98 | GCC2 (GRIP and coiled-coil domain containing 2) | protein interactions | 9648 | 116 | 47 | 19454 | 5460 |
TFPT,TMT1A,DHX16,TTC4,MLLT6,HINT3,ARL4A,FURIN,RPN1,TUBB4B,EXOC3,RAB4A,GJA1,PSMB1,STX6,HNRNPL,YWHAG,LAMP3,DPP4,KXD1,LAMP2,NDC80,RAB5C,YWHAB,RAB9A,KDM1A,UFL1,POLR1D,ATG16L1,BET1,TMOD1,PSMC5,PHF21A,ANAPC2,TUBA1B,SRPK2,CSK,RAB2A,RAB11A,CUL3,NRP1,MAPRE1,UBE2H,LAMTOR1,SPOP,YWHAZ,LMNB1 |
| 2.532e-03 | -5.98 | Cytochrome c oxidase | KEGG pathways | M00154 | 21 | 14 | 7161 | 2463 |
COX6B1,COX7B2,COX7B,COX5A,COX6A2,COX4I1,COX6B2,COX7A1,COX11,COX10,COX8A,COX4I2,COX17,COX6C |
| 2.532e-03 | -5.98 | Cytochrome c oxidase | KEGG pathways | hsa_M00154 | 21 | 14 | 7161 | 2463 |
COX4I2,COX8A,COX10,COX11,COX6C,COX17,COX4I1,COX6B2,COX7A1,COX7B,COX5A,COX6A2,COX6B1,COX7B2 |
| 2.534e-03 | -5.98 | GORAB (golgin, RAB6 interacting) | protein interactions | 92344 | 84 | 36 | 19454 | 5460 |
THRAP3,FARSA,TMEM60,PLPP6,PAEP,LRP10,STX8,BET1L,FGFR1,CTSA,CRKL,STX12,CMTM7,SEC22B,SNAPC5,SELENOK,BET1,NRM,RAB6A,CXCL9,VKORC1L1,MDM2,TRAF3IP3,RCHY1,VAMP3,ARF1,TMEM229B,TMEM11,BCL2L1,TMEM19,VAMP5,VEZT,ATG9A,LMO2,CD81,FBXO7 |
| 2.534e-03 | -5.98 | GPAA1 (glycosylphosphatidylinositol anchor attachment 1) | protein interactions | 8733 | 84 | 36 | 19454 | 5460 |
CCDC47,PRR13,YIPF3,MOXD1,VAPB,RPA2,PTP4A2,TMEM95,GP9,STOM,CRELD1,RPA3,TSPAN15,TMEM106B,LPAR1,HS2ST1,EIF3E,RIGI,GABRG2,FAM20C,CSGALNACT2,SMPD2,AQP2,COX4I1,PIGK,DPEP1,SYNGR1,PRSS8,STARD3NL,AP1G2,GPR173,THY1,ATP5F1B,ARF6,IFI6,ACAP2 |
| 2.534e-03 | -5.98 | TMEM185A (transmembrane protein 185A) | protein interactions | 84548 | 84 | 36 | 19454 | 5460 |
UBTD2,ATP6AP2,SRC,ARL6IP5,CD47,SVIP,YES1,CDCA3,STUB1,HRAS,EPHA2,NAPA,REEP6,RAB2A,TMEM199,LAMTOR2,PYGB,GNB4,RER1,CCNY,CPNE2,NDUFC2,RAP2A,GNA11,NDUFB5,TBC1D24,UQCC2,TMEM185B,PRKCA,GNAQ,GNAZ,VAMP2,STOM,DDX39A,HPCAL1,DAAM1 |
| 2.534e-03 | -5.98 | CHTF18 (chromosome transmission fidelity factor 18) | protein interactions | 63922 | 84 | 36 | 19454 | 5460 |
GSK3A,EEF1AKMT3,CIB2,DCLRE1C,CCNF,APEX1,ESR2,CBX5,EGLN3,SNRNP40,TRIM35,RFC5,HSPB8,CIAO1,GSTM3,MYC,UBXN6,ZBTB38,HSP90AA1,DCTN3,EP300,PCNA,P4HA2,HSPA8,PML,LGI1,JAKMIP1,RFC4,CXCR4,RPA3,IMMP2L,RAD21,RFC2,RFC3,RFXANK,RPA2 |
| 2.538e-03 | -5.98 | MACO1 (macoilin 1) | protein interactions | 55219 | 167 | 64 | 19454 | 5460 |
DNAJC25,SOX2,CCDC47,YTHDF2,CRELD1,RPN1,STIM1,VPS33A,RAB4A,CYP2C9,TMT1A,CNOT6L,FKBP8,CNOT7,KRAS,RAB3B,LAMP3,FAM241A,CNOT2,LAMP2,RAB5C,SMAD9,TMEM190,RHOG,ESYT1,HSD17B11,GJA1,RAC2,RAB35,PTPN1,PLAC9,TMPO,STX6,PPIA,LMAN1,TMEM237,DNAJC1,CDC42,SEC62,YIPF5,OTULINL,RND2,ST7,SSR1,RAB9A,DERL1,RAB5A,STX7,PXMP2,CERS6,SMCP,RAB11A,TMEM255A,SYP,BICD2,LMNB1,RMDN3,ZNF655,ANAPC2,SEC61B,CCNF,B4GAT1,SEC63,SRPK2 |
| 2.540e-03 | -5.98 | Vesicle-mediated transport | REACTOME pathways | R-HSA-5653656 | 650 | 237 | 10285 | 3229 |
COPS7B,DCTN3,STX17,NAPA,ADRB2,RAB1B,CD3G,RAB1A,SNAP23,UBB,STX5,SERPINA1,RAB9A,RAB27A,TRAPPC2L,EXOC3,MAN1A2,SGIP1,HBB,SPTBN1,SNAP91,DENND6B,ARFGAP3,AKT2,TPD52,COPZ2,NAA35,YWHAG,TMED9,COL1A2,CFTR,CALR,RAB30,FTL,VPS28,TRAPPC1,WASL,OPTN,SLC2A8,DYNLL1,HGS,CHMP4C,TFG,MYH2,SEC22A,RHOBTB3,TBC1D16,ALB,BET1L,KIF3C,CHMP5,SPTAN1,ARCN1,ACTR2,CYTH1,EXOC5,SNX18,ARF6,TBC1D17,YWHAH,STX6,COPE,VAMP8,GJC1,TMED7,EXOC8,STX16,NAA30,RAB14,TBC1D24,HBA1,CYTH4,FTH1,TOR1B,CLVS1,MIA2,CNIH1,CD36,USP6NL,COPS7A,CYTH2,VAMP2,AKT1,HSP90AA1,TF,RAB13,KIF2A,SURF4,TSG101,PAFAH1B2,CD59,RAB11B,RALA,FOLR1,PRKAG1,BLOC1S3,DYNC1I1,ARFGAP1,DVL2,RAB32,TRAPPC6B,RAB39B,ARPC2,USE1,DENND2D,AP1S2,TRAPPC6A,SEC22B,VPS4B,KDELR1,TBC1D10C,GOSR2,PREB,RAB33B,GJB1,CTSC,SFN,MIR711,TACR1,DNM2,NAPG,KDELR2,TBC1D1,GABARAP,COPS2,AP1M1,COG1,CBL,OCRL,TRAPPC4,BICD2,GALNT1,GJA1,HSPA8,BET1,KIF1C,TBC1D4,COL3A1,TMED3,RAB11A,YKT6,FZD4,STX18,GOSR1,NECAP2,NECAP1,AP2M1,JCHAIN,SYT2,SYS1,RAB4A,RAB5C,RACGAP1,AP2S1,NEDD8,RGP1,FCHO2,COPS5,CD4,TPD52L1,SEC22C,STX10,CHMP2A,RAB31,MAP1LC3B,COPS4,TBC1D13,MYH1,TBC1D25,AP1G2,KLC2,LDLR,CHMP2B,SNX2,RINT1,HSP90B1,GJB2,DCTN6,DCTN4,AP2A1,CTTN,SCFD1,RAB35,SAR1B,GOLGA5,TFRC,MYO6,DYNC1I2,YWHAB,GRIA1,RAB6B,TMEM115,TRAPPC3,RAB3A,ARF1,UBA52,EXOC1,PAFAH1B3,SEC13,EXOC2,PICALM,YWHAZ,VAMP3,PAFAH1B1,GJA10,SNAPIN,VPS54,SRC,AKT3,TRAPPC10,RAB9B,VPS4A,SNAP29,VTA1,KIF3B,CLVS2,SNX5,RALGAPA2,HP,ARF4,GABARAPL2,GDI2,ARPC3,VAMP7,RAB33A,RPS27A,LMAN1,RAB5A,RAB8B,PACSIN3,PRKAB1,RAB18,RAB6A,GALNT2,SEC23A,GCC1,TRAPPC13 |
| 2.546e-03 | -5.97 | MAPK1/MAPK3 signaling | REACTOME pathways | R-HSA-5684996 | 251 | 100 | 10285 | 3229 |
NEFL,DUSP10,MAP3K11,IL2RA,SPRED2,PSMB9,HBEGF,PSMD6,PSME2,FGF3,RAP1A,IL6ST,SHC3,PSMD12,FGF7,JAK1,CSF2,PPP2R1A,UBB,PTPN11,PSMD14,FGF17,PSMD7,ANGPT1,PSME1,CDK1,PPP5C,SPTBN1,BRAP,CSK,DLG4,PSMA2,PSMB6,PSMB10,IL2,PSMC5,FGFR1,PSMB11,PSMA4,PSMC4,IL6,PSMB5,PSMA3,PSMB1,PSMB7,JAK2,PSMD3,SPRED1,PHB1,PSMD4,IL3,RPS27A,PSMA1,PSMC3,DUSP1,SEM1,PSMB4,SHC1,RASGRP3,PSMA6,PEA15,PSMD1,PSMB2,IL5,HRAS,KIT,LAMTOR2,PPP2CB,CUL3,PSMC1,VWF,LAMTOR3,CAMK2G,IL2RB,FGF16,RAF1,WDR83,UBA52,FGF22,KRAS,MAP2K1,RAP1B,FGF10,DUSP9,SRC,PSMD10,FRS3,PSMB3,PEBP1,PPP2R5E,SPTAN1,PSMA5,FGF23,PAQR3,MET,PPP2R5A,FGF1,DUSP6,YWHAB,IL2RG |
| 2.551e-03 | -5.97 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-monophasic | 15 | 10 | 16828 | 4835 |
FBXW7,ETV6,TP53,CTNNB1,RB1,KIT,PTEN,EWSR1,PIK3CA,SS18 |
| 2.551e-03 | -5.97 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | 15 | 10 | 16828 | 4835 |
ETV6,FBXW7,CTNNB1,KIT,RB1,TP53,PTEN,EWSR1,PIK3CA,SS18 |
| 2.551e-03 | -5.97 | meninges-meningioma-anaplastic | COSMIC cancer mutations | meninges-meningioma-anaplastic | 15 | 10 | 16828 | 4835 |
SMAD4,PTEN,PIK3CA,IDH2,CDKN2C,AKT1,IDH1,NF2,HRAS,KRAS |
| 2.551e-03 | -5.97 | monophasic | COSMIC cancer mutations | monophasic | 15 | 10 | 16828 | 4835 |
PTEN,EWSR1,PIK3CA,SS18,FBXW7,ETV6,TP53,CTNNB1,KIT,RB1 |
| 2.551e-03 | -5.97 | meninges-meningioma-atypical | COSMIC cancer mutations | meninges-meningioma-atypical | 15 | 10 | 16828 | 4835 |
PIK3CA,PTEN,SMAD4,HRAS,KRAS,CTNNB1,NF2,AKT1,IDH1,CDKN2C |
| 2.551e-03 | -5.97 | meninges-meningioma-transitional | COSMIC cancer mutations | meninges-meningioma-transitional | 15 | 10 | 16828 | 4835 |
CDKN2C,AKT1,NF2,HRAS,KRAS,SMARCB1,PTEN,SMAD4,TERT,PIK3CA |
| 2.551e-03 | -5.97 | transitional | COSMIC cancer mutations | transitional | 15 | 10 | 16828 | 4835 |
NF2,AKT1,CDKN2C,HRAS,KRAS,SMAD4,SMARCB1,PTEN,TERT,PIK3CA |
| 2.555e-03 | -5.97 | KMT2B (lysine methyltransferase 2B) | protein interactions | 9757 | 119 | 48 | 19454 | 5460 |
WDR82,RAP1B,SMAD3,THOC2,ATG7,CSNK2A1,ATP1B1,DPY30,PAGR1,SMN1,RIGI,RERE,H3C1,TRIM63,ASF1A,ELF1,TOP3B,SMARCB1,RBPJ,CBX3,RPL37A,CSNK2B,PHF21A,ELK3,ZNF330,VIRMA,ESR2,APEX1,BUB3,NREP,SNRNP40,KANSL3,MYC,PIK3R3,TADA3,MTDH,RPA3,PML,HCFC2,RPP14,CXXC1,BCL6,KDM1A,KLF12,CDKN1A,ANXA7,RPA2,KLF3 |
| 2.558e-03 | -5.97 | Proteasome, 19S regulatory particle (PA700) | KEGG pathways | M00341 | 19 | 13 | 7161 | 2463 |
PSMC4,PSMD12,PSMC1,PSMD1,SEM1,PSMD7,PSMD3,ADRM1,PSMD4,PSMC5,PSMC3,PSMD6,PSMD14 |
| 2.558e-03 | -5.97 | Proteasome, 19S regulatory particle (PA700) | KEGG pathways | hsa_M00341 | 19 | 13 | 7161 | 2463 |
PSMD6,PSMD14,PSMC5,PSMC3,ADRM1,PSMD4,PSMD3,PSMD7,PSMC4,SEM1,PSMC1,PSMD1,PSMD12 |
| 2.569e-03 | -5.96 | regulation of SMAD protein signal transduction | biological process | GO:0060390 | 75 | 34 | 18204 | 5365 |
EMILIN1,TGFBR2,MIR130A,NOG,PPARG,CSNK2B,MIR23A,MIR140,SMAD4,MIR146A,GREM1,MIR205,MIR26B,LDLRAD4,FAM89B,DKK1,HFE,TGFB3,MIR885,ACVR1,CCN3,BMPR2,MIR195,EID2,MIR145,MIRLET7G,GLCE,SPTBN1,TWSG1,JAK2,MIR204,BMPR1A,TGFB2,MIR101-1 |
| 2.569e-03 | -5.96 | cellular response to external stimulus | biological process | GO:0071496 | 75 | 34 | 18204 | 5365 |
TLR3,MTPN,PDE2A,SLC2A1,TLR7,BAD,IL13,MAP3K14,NFKB1,SLC38A2,BAK1,IGF1R,CRADD,BAG3,DAG1,BCL10,FAS,GADD45A,IRF1,MYD88,SOX9,IL1B,CD40,TMEM87A,KCNJ2,GCLC,F11R,ATP1A2,PTGER4,TLR4,ITGA2,TLR8,LTBR,TLR5 |
| 2.572e-03 | -5.96 | CCDC106 (coiled-coil domain containing 106) | protein interactions | 29903 | 56 | 26 | 19454 | 5460 |
CSNK2A1,PRPF31,ATF4,CRMP1,ARMC8,CSNK2B,FGFBP1,CEBPG,LRIF1,CEP19,MAGOHB,RPL13A,RAF1,TP53,RPL26L1,POMT2,CAMK1,SDCBP,ERG28,GID4,S100B,EIF1AD,NKAPD1,RPL28,RANBP10,EEF1G |
| 2.572e-03 | -5.96 | Ppp2ca (protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform) | protein interactions | 19052 | 56 | 26 | 19454 | 5460 |
NLRP3,CDC73,CCT2,ZCCHC9,ZMYND11,FGFR1OP2,BMPR1B,CCT7,SLMAP,CTTNBP2NL,TCP1,INTS12,IGBP1,MOB4,PPP2R1A,ING5,CCT5,USP6NL,MRPS7,MRPL22,SSR3,STK26,TRIM5,SIKE1,CCT8,HELLS |
| 2.572e-03 | -5.96 | ARMC12 (armadillo repeat containing 12) | protein interactions | 221481 | 56 | 26 | 19454 | 5460 |
FA2H,CORO1C,CALML5,FABP5,SNX1,RBBP4,ATP5F1B,TMOD3,TUFM,H2AZ2,HBA1,GAD2,SEPTIN7,TRIM21,CORO6,H2BC14,HSPA5,SPG21,DDX39A,EHHADH,H1-5,EFHD1,HECTD1,JUP,EZH2,TUBB4B |
| 2.572e-03 | -5.96 | electron transfer activity | molecular function | GO:0009055 | 104 | 45 | 18094 | 5411 |
CYC1,IDH3B,COX7A1,NDUFB5,NDUFB4,NDUFA5,NDUFS8,DEGS1,CYB5A,NDUFA2,P4HA2,COX4I2,AKR7A2,NDUFA1,GLRX2,NDUFB10,NDUFA12,NDUFB6,NDUFV2,COX6B1,COX8A,COX5A,UQCR11,IDO1,DHRS3,NDUFB7,UQCRH,HSD17B6,NDUFA4,AKR1B1,SDHC,SDHB,NDUFS2,ETFB,GFUS,COX7B,NDUFC2,GPX2,NDUFB8,COX4I1,NDUFS6,COX11,NDUFS3,ETFA,UQCRC1 |
| 2.575e-03 | -5.96 | AVPR2 (arginine vasopressin receptor 2) | protein interactions | 554 | 122 | 49 | 19454 | 5460 |
MAD2L2,GNB1,SC5D,SERINC1,INTS12,GPR89A,SELENOT,STUB1,SLC30A5,CERS6,MAVS,DERL1,TMEM160,PIGW,GOLGA5,ST7,SYNGR2,SLC19A2,PAQR3,NOP9,SPPL3,C1QTNF1,MFSD5,GJA1,SLC39A10,COMT,FITM2,OSBPL8,NDUFB8,EXOC2,GNG2,SLC41A1,FAM20B,MZT2B,SLC25A46,GXYLT2,RINT1,TMED1,ATP2B4,HGS,SLC35F1,EXOC3,SURF4,YIPF3,TNPO2,ZMYM4,MACO1,IPO8,TCAF2 |
| 2.579e-03 | -5.96 | negative regulation of secretion by cell | biological process | GO:1903531 | 151 | 61 | 18204 | 5365 |
IL1B,LILRB1,VAMP8,ADORA1,IL12A,PPP3CA,GABBR1,P2RY1,DPH3,KCNJ11,DRD3,LEP,STXBP6,ADTRP,CD200,OPRM1,FCGR2B,PTPN11,VPS4B,IL12B,NDUFAF2,ENY2,ADIPOQ,KCNB1,UCP2,ACVR1C,RAB33B,JAGN1,GNAO1,NPVF,NEO1,RSAD2,ASIC1,SFRP1,RAP1A,CCN3,ERP29,CRHBP,GNAI2,OSM,GHRL,GNAZ,GJA1,TNFRSF1B,TSPO,MIR146A,CNR1,HADH,CARTPT,INHA,VAMP3,CCR2,SYT4,OPRK1,FGF23,RAP1B,NPY5R,CRY1,CHGA,FKBP1B,UCN |
| 2.583e-03 | -5.96 | TYK2 (tyrosine kinase 2) | protein interactions | 7297 | 158 | 61 | 19454 | 5460 |
EIF2AK2,RAN,PRMT5,GPX1,STAT2,STAT1,TXNRD2,PTPN11,GMNN,PPP1CC,IFNAR1,WDR20,CCT2,HSP90AA1,OAT,JAKMIP1,XRCC5,DVL2,CXCR4,DDX5,OXCT1,FABP4,FAXC,IL6ST,PIH1D1,ALYREF,PTPN1,DNM2,TCP1,HNRNPL,CCT7,LRRC61,PTP4A3,MOV10,HMGA1,SIVA1,PIK3R1,SIAH2,COPS5,SLC2A1,HSPB1,BCL2L1,CBL,CCT8,BAG2,IDH1,FHL3,JAK1,RUVBL2,KLF10,TGFBR2,RUVBL1,HNRNPK,TF,SOCS2,CCT5,TOP3B,LPAR6,CDH8,CRKL,GHR |
| 2.583e-03 | -5.96 | ARID1B (AT-rich interaction domain 1B) | protein interactions | 57492 | 158 | 61 | 19454 | 5460 |
CPSF1,FBLN5,ENO1,PRMT5,PYGM,SNRNP40,ACTB,VIRMA,CREBBP,HNF1B,MYC,CUL2,SMARCE1,IRF1,AR,SMAD2,RPA3,SMARCD3,FOS,RNF10,DDIT3,B9D2,SS18,ACTL6A,PPARG,RPA2,KLF3,RPRD1B,ELF5,HEXIM1,PAX9,KLF4,SMAD3,BRD9,CAND1,NUP35,IRF4,WWP2,BCL7C,ELOC,SMAD4,AGR2,SMAD9,POU5F1,RASSF8,LHX2,SNIP1,BCL7B,HAPSTR1,FAM168A,KRAS,ASF1A,PAX6,MDC1,RIGI,SUPT5H,SOX2,EGR2,H2AX,SOX9,SMARCB1 |
| 2.591e-03 | -5.96 | TBC1D4 (TBC1 domain family member 4) | protein interactions | 9882 | 125 | 50 | 19454 | 5460 |
VPS16,CAMK2G,TOLLIP,RPL3,CHAMP1,ACTR2,CTDSP2,RBM12,TP53,EGLN3,HNRNPL,KRT8,PPP2CB,YWHAB,TOPBP1,YWHAG,TP53INP1,YWHAH,LRRC40,UBXN6,KDM1A,SMC4,MIS12,BAP1,RPA3,TMOD1,RPA2,ELFN2,CDKN1A,CCNA2,WDR77,UBA52,EIF4E3,VIRMA,TMOD3,TAX1BP1,GSK3A,PHF21A,CCNF,NFKBIA,UBE2H,FBXW11,YWHAZ,H2BC9,TBC1D1,EMILIN1,MYC,AKT1,CUL2,SFN |
| 2.591e-03 | -5.96 | ZNF250 (zinc finger protein 250) | protein interactions | 58500 | 125 | 50 | 19454 | 5460 |
TOP3B,DDX39A,TRAF2,GUCD1,ZC4H2,CBX3,ZFP1,GRAP2,UBE3A,PICK1,RIGI,CDCA7L,GAS8,ZNF345,ZNF473,ANKRD50,ZNF175,SSX2IP,STX1A,CDR2L,SPRED2,DPPA2,PLEKHF2,TMCC2,FAM161A,RPA2,APOBEC3C,CDR2,SPECC1L,ZBTB6,DVL2,RPA3,LDOC1,CUL3,ZNF250,LMO2,CEP70,GMNN,CCDC85B,PRPF31,ZNF668,TRIM23,ZNF330,TRIM27,HEXIM2,ZCCHC7,SYNE4,MAGOHB,TRIM54,TRAF1 |
| 2.591e-03 | -5.96 | WNK1 (WNK lysine deficient protein kinase 1) | protein interactions | 65125 | 125 | 50 | 19454 | 5460 |
GSTM3,YWHAH,YWHAG,COPS5,XPO1,TIAM1,HNRNPD,MED4,STAMBPL1,YWHAB,EEF1AKMT3,METTL6,EIF2B2,RANGRF,TOP3B,KBTBD4,TULP3,AAMP,ZYX,MAEA,BAG2,FHL3,TOLLIP,AKT1,MYC,MLF1,SFN,BAG3,CHCHD4,YWHAZ,CCNF,EIF3K,SYT2,UBE2I,RAPGEF5,MAP3K3,VIRMA,ESR2,KLHL3,CDC42,RPA2,CD46,PICALM,MAP2K1,OXSR1,RPA3,HSPA8,SQSTM1,HSCB,ADRB2 |
| 2.591e-03 | -5.96 | STXBP1 (syntaxin binding protein 1) | protein interactions | 6812 | 125 | 50 | 19454 | 5460 |
RRP7A,PAPOLA,IRF2BP1,SUCLG2,PHTF2,VIRMA,PTP4A2,RPA2,PICALM,PRKCA,SPTBN1,PPP1R8,SHMT1,EHD1,GPM6A,OXCT1,GRPEL1,CERS6,BOLA3,SOD1,PRKCB,SQSTM1,MTDH,NUP50,SHC1,TM4SF18,STX1A,ID1,HAX1,CENPP,PLPP4,LRRC40,KCTD3,SNAP25,KCTD10,ARMC1,UBE2N,GJA1,STX5,PPID,ARPC3,ACTR2,CDK5R1,HGS,CMPK1,STX11,OLA1,TUSC3,CDK5,SLC39A7 |
| 2.591e-03 | -5.96 | UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats) | protein interactions | 55075 | 125 | 50 | 19454 | 5460 |
ISG15,PNMA5,JPH4,RAF1,NUPR1,IFT22,PICK1,PPP1R12A,AHCYL1,FBXO25,MEPCE,KRAS,CTNNB1,HDAC6,YWHAH,YWHAG,INSYN1,NDC80,WWP2,IFI16,YWHAB,RHOG,KRT8,GJA1,HRAS,SYNCRIP,RAB35,RHOH,HNRNPL,BORCS6,PPP1CB,WDR77,UBE2M,STAMBP,FGFR1,CORO6,TIGD7,FBXW7,STAU1,PPP1CC,DNAJC5,BTF3,MYC,HNF1B,RHOB,YWHAZ,GUCY1B1,APEX1,SH3BGRL,RNASEH1 |
| 2.594e-03 | -5.95 | DGKI (diacylglycerol kinase iota) | protein interactions | 9162 | 7 | 6 | 19454 | 5460 |
AP2M1,RAP1A,H1-1,PHB2,RASGRP3,PRNP |
| 2.594e-03 | -5.95 | Gdi2 (GDP dissociation inhibitor 2) | protein interactions | 14569 | 7 | 6 | 19454 | 5460 |
RAB4A,CCNF,RAB2A,RAB1A,RAB6A,PTEN |
| 2.594e-03 | -5.95 | KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1) | protein interactions | 3779 | 7 | 6 | 19454 | 5460 |
RIGI,CYB5A,EWSR1,CLCA1,KCNMA1,STX8 |
| 2.594e-03 | -5.95 | HMGXB3 (HMG-box containing 3) | protein interactions | 22993 | 7 | 6 | 19454 | 5460 |
PFDN1,SMN1,CDKN1A,ANXA7,TOP3B,CDK4 |
| 2.594e-03 | -5.95 | Psma2 (proteasome subunit alpha 2) | protein interactions | 19166 | 7 | 6 | 19454 | 5460 |
ADRM1,CCNF,HSPA5,CFTR,TUBA1A,HSPA8 |
| 2.594e-03 | -5.95 | ZNF366 (zinc finger protein 366) | protein interactions | 167465 | 7 | 6 | 19454 | 5460 |
UBE3A,CEP70,PSMA3,KLHL15,TRIM54,AKAP8L |
| 2.594e-03 | -5.95 | FIBCD1 (fibrinogen C domain containing 1) | protein interactions | 84929 | 7 | 6 | 19454 | 5460 |
TNFSF8,CLDND1,ATG7,TMUB2,TSPAN3,APEX1 |
| 2.594e-03 | -5.95 | Pank4 (pantothenate kinase 4) | protein interactions | 269614 | 7 | 6 | 19454 | 5460 |
LDHA,GCC1,HSP90AB1,LDHB,TUBA1B,MYBL2 |
| 2.594e-03 | -5.95 | PHF24 (PHD finger protein 24) | protein interactions | 23349 | 7 | 6 | 19454 | 5460 |
TRIM35,SPPL3,PPP1R18,THBD,GNAI3,PFDN5 |
| 2.594e-03 | -5.95 | Rxra (retinoid X receptor alpha) | protein interactions | 20181 | 7 | 6 | 19454 | 5460 |
MECR,NONO,EP300,PPARG,SIN3A,SMARCD3 |
| 2.594e-03 | -5.95 | ABCC9 (ATP binding cassette subfamily C member 9) | protein interactions | 10060 | 7 | 6 | 19454 | 5460 |
EEF1G,KCNJ11,LDHA,KCNJ8,STX1A,HSPB2 |
| 2.594e-03 | -5.95 | ENPP5 (ectonucleotide pyrophosphatase/phosphodiesterase family member 5) | protein interactions | 59084 | 7 | 6 | 19454 | 5460 |
TIAM1,KRAS,SIGLECL1,HNRNPL,CFTR,SKP1 |
| 2.594e-03 | -5.95 | FUT7 (fucosyltransferase 7) | protein interactions | 2529 | 7 | 6 | 19454 | 5460 |
HSPA5,TLR10,GPR160,YTHDF1,CXCL9,CTXN3 |
| 2.595e-03 | -5.95 | INTS5 (integrator complex subunit 5) | protein interactions | 80789 | 155 | 60 | 19454 | 5460 |
SNRPD3,PPP2CB,POLR2L,CAMLG,NABP1,NAIF1,SKIC8,CDK12,XPO1,LAMP3,TNF,KRAS,ZNF592,SEM1,CTNNBL1,GTF3C3,PSMD12,SNRPG,COPS4,SKA3,AQP3,POLR2D,POLR2C,POLR2G,TAF2,CYB5B,TOP3B,CENPM,PPP2R1A,MGARP,PSMD4,RPL35,APLNR,POLR2B,ROMO1,ERH,ESR2,LMBR1L,CD79B,S100A6,CHRM4,INTS10,INTS12,PSMD14,MAT2A,MED22,GPR17,ZNF687,PSMD1,NPTN,CLU,CXCR4,SLC39A9,PML,MED23,LUC7L3,INTS6L,TOMM22,NPY2R,HCST |
| 2.595e-03 | -5.95 | SDAD1 (SDA1 domain containing 1) | protein interactions | 55153 | 155 | 60 | 19454 | 5460 |
RPL35,RBBP4,FBXO22,RPL13A,APEX1,ESR2,VIRMA,PSPC1,TNFRSF1B,ZNF330,PRKRA,FGFBP1,MECP2,ATG3,ZBTB38,NSA2,RIT1,MYC,NPM3,STAU1,COIL,G3BP2,APOBEC3C,RPA2,RPLP0,RPS14,ATG16L1,SYK,RPS10,RPS16,CGAS,RBM42,CDC5L,CEP19,FBXO32,MRTO4,DDX23,SNRNP70,KPNA1,DRG1,IFI16,PLEKHO1,WWP2,DDRGK1,KRAS,H3C1,KPNA2,RPL28,SSRP1,RPL31,RPL3,COX8A,RPS24,RBM34,HBP1,SRP72,RAF1,MAGEB10,SOX2,RPL15 |
| 2.603e-03 | -5.95 | GAB2 (GRB2 associated binding protein 2) | protein interactions | 9846 | 128 | 51 | 19454 | 5460 |
SYK,SIPA1L1,JUP,AGAP1,MET,RTKN,FAM53C,STK38,PIK3R2,HSPA5,RPL7A,SFN,FAM110B,PTPN11,AKT1,YWHAZ,TBC1D25,RAN,GAB1,VIRMA,SRC,DDX39A,CRKL,GRAP2,TRAPPC13,HSPD1,TRAPPC1,TESK2,KRAS,SRSF12,PIK3R1,MAPK4,YWHAH,GRAP,XPO1,YWHAG,NCK1,SHC1,TRAPPC2L,EIF5A2,HSPB1,YWHAB,CD247,TRAPPC4,EIF4E2,HRAS,ETV6,TRAPPC3,KCTD3,PPIA,TRAPPC6B |
| 2.603e-03 | -5.95 | BUB1 (BUB1 mitotic checkpoint serine/threonine kinase) | protein interactions | 699 | 128 | 51 | 19454 | 5460 |
KDM1A,RPA3,TEX264,MIS12,CDK1,RPA2,FBP2,MAP2K1,STX17,TMOD1,RDH12,IGFBP3,BUB3,MAD2L1,CDC20,SFRP4,ZNF189,SEC61B,ANAPC2,PHF21A,ANAPC4,CDKN2AIP,CDC16,AKT1,DSN1,OST4,MLF1,HSD17B3,FBXO7,CFAP161,BRINP3,TRMO,ANP32B,ZYX,BAG2,GALNT12,CDK8,SPC24,FBP1,SMAD1,PPP3R2,FZR1,NKAP,NUF2,CDC5L,HRAS,PPP2CB,TDRD7,SHC1,HAX1,NDC80 |
| 2.603e-03 | -5.95 | BTK (Bruton tyrosine kinase) | protein interactions | 695 | 128 | 51 | 19454 | 5460 |
GTF2I,PRKCB,HADHA,MET,PRKCA,TIRAP,SYK,LPXN,PIP5K1A,SMURF1,GNB1,ATP5F1B,STAT5A,PRKCE,GAB1,RPS3,TLR8,HSP90AA1,STK11,FAS,PIP4K2C,TLR9,ATP5F1A,AR,MYC,PIK3R3,RIGI,KIT,KRAS,JAK1,EWSR1,MYD88,PIK3AP1,TLR4,GNAQ,TUBB4B,FASLG,TP53,PRKCQ,MDM2,TLR6,HSP90AB1,CAV1,TTC9C,CORO1C,HRAS,ITK,CBL,BECN1,GNG2,GAPDH |
| 2.605e-03 | -5.95 | ARFGAP2 (ADP ribosylation factor GTPase activating protein 2) | protein interactions | 84364 | 152 | 59 | 19454 | 5460 |
ACTB,MAD2L1,ARF1,EIF2AK2,B4GALT1,SEC61B,UBE2I,BICD2,ARFGAP3,NTRK3,IGF2BP1,RAB2A,PXMP2,UNC45A,RPA3,HSPA8,DERL1,RAB5A,CTBP1,RPA2,FGFR1,SSR1,TMOD1,UBE2M,FUT8,BET1,CDC42,ST7,RAB1B,CAND1,STX6,ZBTB2,CAV1,HSP90AB1,MGME1,EED,GJA1,TSG101,RHOG,ANKRD49,FAM20C,XPO1,YWHAH,ASF1A,MRPS18C,ARF4,RIGI,RAB1A,TMT1A,SLC39A7,HSD17B10,BAG2,EZH2,TRAPPC13,FURIN,ATP5PB,ARFGAP1,NUP153,ACTR1A |
| 2.605e-03 | -5.95 | TRIP11 (thyroid hormone receptor interactor 11) | protein interactions | 9321 | 152 | 59 | 19454 | 5460 |
RAB5A,RAB9A,PXMP2,STX7,CLDN4,ATG16L1,BET1,RND2,CDC42,FGFR1,ARF1,ATXN1L,PSMC5,VIRMA,RAB2A,OR6X1,CSK,SFN,RAB11A,CHPF,LAMTOR1,BRCA1,EPHA2,NRP1,TMT1A,NTRK2,RAB3B,BACH1,ARF4,SAR1B,WDR37,VPS33A,EXOC3,RAB4A,DISC1,FURIN,GJA1,RB1,COPS2,KRT8,RAC2,SPTAN1,RHOH,STX6,CAV1,NUP35,DPP4,LAMP2,KXD1,RAB5C,SLC25A46,LAMP3,YWHAH,YWHAG,INSYN1,RHOG,ASB7,MED4,YWHAB |
| 2.613e-03 | -5.95 | ATP6AP1 (ATPase H+ transporting accessory protein 1) | protein interactions | 537 | 131 | 52 | 19454 | 5460 |
DNAJC1,VAMP7,MYEF2,PTPN1,COQ8A,RAC2,ATP6V1A,HBA1,ESYT1,SLC2A1,RHOG,EMC4,MOV10,EMC6,KRAS,FKBP8,GTF3C3,PSMD12,EMC2,PICK1,EZH2,NCR3,INSIG2,DNAJC25,ATP6AP2,SEC63,NR1I2,VPS72,CYB5R3,RMDN3,LAMTOR1,RIT1,FIS1,HNRNPAB,GORASP2,BTF3,GPC1,ATP6V1G2,EMC1,ATP6V1G1,TMEM106B,RHOU,TMEM185A,SYVN1,LMNA,ATP6V1C1,ATP6V0E1,ST7,CDC42,CNPY3,RND2,OTULINL |
| 2.616e-03 | -5.95 | BABAM2 (BRISC and BRCA1 A complex member 2) | protein interactions | 9577 | 87 | 37 | 19454 | 5460 |
DHRS7B,RPA2,DNAJC25,ZMYM3,SYK,TOP3B,RAF1,TP53,PPDPF,MSH6,FKBP8,MDC1,TFG,SRSF2,SSR3,FAM168A,TMX3,PALM2AKAP2,RPA3,HNRNPA2B1,CBL,FAS,UBE2D1,BRCA1,COPS5,BABAM1,CUL3,WWP2,CHI3L1,MDM2,DYRK1A,ESR2,VIRMA,HNRNPL,SUMO2,OPTN,PHB1 |
| 2.616e-03 | -5.95 | PLCG2 (phospholipase C gamma 2) | protein interactions | 5336 | 87 | 37 | 19454 | 5460 |
NME2,SHC1,FCER1G,PTTG1,NTRK3,PIK3R1,MYC,PSMD3,PTPN11,AR,LAT2,ESD,TWIST2,LCP2,ELK1,VIRMA,JAK2,ITK,GAB1,RPA2,EPYC,FGFR1,PRKCA,MET,SETD9,ATG16L1,SYK,TP53,CDC42,KIT,KCTD17,SLC35A2,RIGI,BCL6,PIK3AP1,HSPD1,JAK1 |
| 2.616e-03 | -5.95 | NKTR (natural killer cell triggering receptor) | protein interactions | 4820 | 87 | 37 | 19454 | 5460 |
RIT1,SNRNP70,DDX23,MECP2,SNRPB,YWHAG,CSNK2A1,YWHAH,ZCCHC10,PRPF19,ZBTB2,SRPK2,NKAP,SNRNP40,RPL13A,PRNP,RNASEH1,LDLR,CSNK2B,SNRPD2,RPL15,CD2BP2,ZNF263,ATG16L1,RPS14,RAF1,RPL17,SRSF4,SAP18,NUP42,HMGB1,KRAS,SRSF7,ZC3H11A,NKAPD1,SNRPA,SNIP1 |
| 2.616e-03 | -5.95 | CDK19 (cyclin dependent kinase 19) | protein interactions | 23097 | 87 | 37 | 19454 | 5460 |
MED27,MED21,MED10,MED29,MED4,RB1CC1,MED22,CUTA,MCM4,MCM3,HNRNPL,POLR2I,MED17,POLR2B,ESR2,CYRIB,MYEF2,PRMT5,CDK8,MED23,POLR2G,POLR2C,MED31,GNAQ,WDR77,MED9,MED30,RPAP2,FBXL19,MED11,STK38,BCL6,CLU,AZGP1,LSM14A,MED13L,SRSF7 |
| 2.616e-03 | -5.95 | TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B) | protein interactions | 9014 | 87 | 37 | 19454 | 5460 |
PYGM,PGR,MPP1,RPL13A,SURF6,ESR2,TRIM44,PRKRA,TRIM24,MECP2,CCT2,ATG3,BRCA1,OAZ1,RPL10A,RIT1,CALR,MYC,ZCCHC10,RRN3,ATG7,THAP7,KRAS,NPM3,H3C1,RPL4,STAU1,RPL28,RPL17,RPL3,EP300,APOBEC3C,RPLP0,RAF1,TP53,TAF1D,RPL15 |
| 2.619e-03 | -5.94 | APOBEC3D (apolipoprotein B mRNA editing enzyme catalytic subunit 3D) | protein interactions | 140564 | 146 | 57 | 19454 | 5460 |
LARP4B,ZNF326,MRPS34,APOBEC3C,MRPS18A,RPL26L1,ZNF574,PABPC5,RBMS2,MRPL41,MRPL17,RPS15,MRPS7,MRPL20,SF3B1,MRPS25,MRPS16,CASC3,HERC4,NSA2,ELAVL2,NOP16,HNRNPC,APOBEC3B,MRPS21,IREB2,RPS3,MRPL13,PRKRA,POLR3B,MRPL47,STRBP,THRAP3,MRPS33,MRPS17,PABPC1,RPL31,SRSF8,MRPS11,DNAJB4,ZC3H11A,MRPS26,MRPS35,MOV10,APOBEC3F,TRA2A,MRPL9,CGAS,LYAR,RPS10,HNRNPL,MRPL24,SRSF10,KRR1,MRPS9,SYNCRIP,AIP |
| 2.619e-03 | -5.94 | ANKRD11 (ankyrin repeat domain containing 11) | protein interactions | 29123 | 146 | 57 | 19454 | 5460 |
EGLN3,HNRNPL,SPMIP5,SYNCRIP,HRAS,CDR2L,CDC23,NAB2,ZNF688,DDX23,AGR2,CSNK2A1,YWHAG,YWHAH,SPATA2,CDCA7L,SSRP1,KRAS,TRIM37,RPS24,RPL31,RINT1,FAM136A,SPRY1,TNNI1,PPARA,TRAF2,CFAP68,VDR,TOP3B,APEX1,SRC,VIRMA,ESR2,TXN,TRIM54,FBXO22,CSNK2B,ZNF655,PTEN,ZNF330,CCHCR1,PEA15,SERTAD3,GPRASP3,NTAQ1,KPNA6,DNAJC8,RACGAP1,COIL,HDAC3,HDAC5,TFIP11,HECTD1,CDK7,PTAR1,CCN3 |
| 2.623e-03 | -5.94 | TMEM33 (transmembrane protein 33) | protein interactions | 55161 | 143 | 56 | 19454 | 5460 |
VIRMA,ESR2,NDN,CCNF,LMBR1L,UBE2H,BTF3,USP14,DNAJC5,MYC,CUL3,UFL1,RNF5,STAU1,RER1,ADRB2,SYVN1,HSPA8,NMRAL1,AKAP1,RNF113A,RPA3,PEBP1,TMEM106B,CAV2,PIH1D1,RPA2,GRM2,PPP1CB,CFTR,CDK7,RPS14,BET1,PGRMC1,ELK1,CDK9,PTP4A3,EGLN3,NUP35,MARCHF4,FZR1,PHB1,RB1CC1,PEX3,MAP3K14,DDRGK1,ADIPOR2,PSEN1,RNF26,BCKDK,RPN1,MAP1LC3B,TUBA1A,TULP3,RAF1,CCDC47 |
| 2.623e-03 | -5.94 | DCTN4 (dynactin subunit 4) | protein interactions | 51164 | 137 | 54 | 19454 | 5460 |
RNF181,TUBB4B,SKA3,CAPZA2,ACTR1A,TOP3B,KBTBD4,RPL28,MSH6,CAPZA1,RIGI,KRAS,DYNC1I1,KPNA2,HAPSTR1,ACTR1B,DNAJC7,USP15,ARMC8,CCL4L1,SKIC8,EGLN3,UQCRH,HMG20A,DYNC1I2,FBXO32,ACACA,DCTN4,AKR7A2,PAFAH1B1,TRA2B,SMC4,RAB5A,DCTN3,BAP1,DCTN6,BMERB1,RIT1,MAPRE1,BRCA1,BTF3,MCM4,PCCB,MYC,MED22,RAB11A,POLR2B,ESR2,DYNLL1,RBBP4,ACTB,GANAB,PRMT5,PNMA1 |
| 2.623e-03 | -5.94 | GNA13 (G protein subunit alpha 13) | protein interactions | 10672 | 137 | 54 | 19454 | 5460 |
CLDND1,GNB4,TMEM185A,RAMAC,HSPA8,PRKCB,RPA3,RHOU,CXCR4,METTL14,GPR35,ISOC1,RPA2,DUSP22,TSHR,EBLN2,ESR2,DUSP3,GNB1,EFNA5,PPP5C,PRKCE,GIMAP4,CTTN,GNG12,S1PR4,CDC73,RHOB,FYTTD1,GPR17,TAS2R7,MRPS18C,TOLLIP,TRMO,EPHA4,KRAS,SLC16A1,GNG5,STX8,CCR1,SPSB3,CA14,TFCP2,GNG10,GNG3,FBXO32,SYNCRIP,AIP,CTNNB1,HDAC6,GNG2,CD81,USP3,ATG9A |
| 2.623e-03 | -5.94 | TNFRSF10A (TNF receptor superfamily member 10a) | protein interactions | 8797 | 137 | 54 | 19454 | 5460 |
RHOB,IFNAR1,TUFM,TNFAIP3,CUL3,PYCR2,UBB,NDUFAF4,APEX1,NDFIP1,RHOJ,DYNLL1,PRMT5,NDUFA5,SDCBP,CDK1,ACAA2,CDC42,RND2,IDH3B,WDR77,TNFSF10,NDUFS2,LSM12,SQSTM1,RAB9A,RHOU,BMPR1A,LRP10,CBL,BTN2A2,BCL10,RHOG,YWHAG,DDRGK1,ATG9A,RHOH,MPP1,GATD3,RAC2,CD4,COQ8A,HDHD5,COX4I1,UGCG,GFM2,TMEM94,NUDT19,ACVR1,TRAF2,UBL4A,S100A10,TGFBR2,FBXO11 |
| 2.624e-03 | -5.94 | VPS53 (VPS53 subunit of GARP complex) | protein interactions | 55275 | 140 | 55 | 19454 | 5460 |
HMG20A,NUF2,STX6,THOC1,RAB1B,KRT8,EED,RPRD1A,THOC2,EXOC2,TRAPPC2L,PSMD7,SMAD4,EXOC1,INSYN1,LAMP3,RAB5C,ATG9A,LAMP2,IMMP2L,FLOT1,KRAS,RAB1A,TFPT,TRAPPC13,POLR2C,RAB4A,TFRC,SNAP29,MAX,VIRMA,PHF21A,PTEN,GANAB,LMBR1L,CCHCR1,IGF2BP1,CHRAC1,LAMTOR1,RAB11A,GPR17,SYCE3,RAB2A,STX7,OIP5,KDM1A,RAB9A,UBE2M,VPS54,GIT2,GOLGA5,CTBP1,FUT8,NUP62,PTAR1 |
| 2.624e-03 | -5.94 | SLC39A10 (solute carrier family 39 member 10) | protein interactions | 57181 | 140 | 55 | 19454 | 5460 |
STX7,LPAR1,RAB5A,DERL1,RAB9A,RHOU,TSPAN15,SLC25A3,RND2,OTULINL,HCST,CDC42,SEC62,CLDN4,RHOJ,TNFRSF9,GPR173,CCNF,S1PR4,MARCHF3,LAMTOR1,RHOB,BRCA1,DNAJC5,RAB2A,ST3GAL1,MYC,RAB11A,FLOT1,KRAS,LPAR2,RND3,RPN1,SIGLECL1,AQP3,RAB4A,COMTD1,DIRAS3,STX6,EGLN3,CAV1,ARF6,RHOH,GJA1,RNF128,SPINT2,RAC2,RAB35,HRAS,RHOG,LAMP3,P2RY10,CCR6,LAMP2,RAB5C |
| 2.624e-03 | -5.94 | ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1) | protein interactions | 10565 | 140 | 55 | 19454 | 5460 |
CTNNB1,LAMP3,DPY30,LAMP2,PDIA3,SMAD4,SPINT2,KRT8,GJA1,AIFM1,HRAS,STX6,ARF6,DDX39A,MGARP,EXOSC3,RAB4A,SIGLECL1,EFNB1,TMEM87A,OSTM1,HNRNPDL,MSH6,RIGI,FKBP2,SEMA4C,AKAP12,RAB11A,PSMA4,GPR17,RAB2A,CSGALNACT1,BRCA1,ATG3,LAMTOR1,MSN,PRMT5,LMBR1L,VIRMA,NCKAP1,MRPL23,NPY2R,BET1,PSMC4,FAM234A,NUP62,ACACA,RPA2,STK26,RAB9A,HSPA8,RPA3,CD40,SLU7,NPTN |
| 2.627e-03 | -5.94 | B cell activation | biological process | GO:0042113 | 189 | 74 | 18204 | 5365 |
ST3GAL1,IL7,TBC1D10C,MEF2C,EXOSC3,EZH2,SLC25A5,CHRNB2,SWAP70,FOSL2,SYVN1,HDAC5,PRKCB,IRF8,RAG1,BST2,GAPT,SKAP2,TICAM1,IFNB1,DNAJB9,IFNA2,IGBP1,LAT2,NBN,MSH6,NHEJ1,IL4,CEBPG,KIT,IFNK,CD38,TPD52,PIK3R1,PIK3R2,SLC39A7,CD86,IFNA10,IL2RG,CMTM7,PHB1,TRAF3IP2,BAX,BAK1,IL6,IL21,PIK3R3,TP53,IL10,RBPJ,NOTCH2,EP300,ITM2A,TLR4,BATF,CD40LG,LRRC8A,IFNA13,PHB2,CCR6,RNF8,DCLRE1C,STAT6,FCGR2B,AKAP17A,HSPD1,BCL6,FOXP3,RABL3,CD40,TOP2B,SYK,CD79B,SASH3 |
| 2.629e-03 | -5.94 | CASK (calcium/calmodulin dependent serine protein kinase) | protein interactions | 8573 | 204 | 76 | 19454 | 5460 |
DNAJC5,PPP1CC,LIN7B,EPS8,RSPH1,MYC,UBE2H,MAPRE1,KCNJ2,RHOB,LAMTOR1,DLG4,CCNF,FCHSD2,SRPK2,VIRMA,DUSP10,APEX1,DUSP3,RHOJ,F11R,FBXL19,RND2,CDC42,CIMIP1,IL15RA,FGFR1,RPA2,SDC2,TRIM22,HADHA,RPA3,RHOU,LIN7C,MARS1,BNIP3L,GCNT3,SPATA2,RAB3A,ID1,PPM1B,TIAM1,RHOG,RAC2,GJA1,DLGAP4,SDC4,RBM5,SRP14,RAB35,SLAIN2,CAV1,SURF6,CDK9,MAPRE2,RHOH,IL18,HNRNPL,ARF6,EEF2,KIF2A,MLLT6,DLG3,NUPR1,HGS,CASK,MTMR2,NTN4,DLG1,ATP2B4,EIF1AD,FLOT1,RIGI,TRIM26,EPHA4,KRAS |
| 2.631e-03 | -5.94 | TNF | smart domains | SM00207 | 16 | 10 | 9717 | 2575 |
TNF,FASLG,TNFSF13,LTB,TNFSF10,LTA,TNFSF15,TNFSF8,CD40LG,TNFSF12 |
| 2.640e-03 | -5.94 | positive regulation of neuron apoptotic process | biological process | GO:0043525 | 67 | 31 | 18204 | 5365 |
MIR200A,TGFB2,TP53,PCSK9,SRPK2,MAP3K11,TNF,CDC42,PHB1,NUPR1,CASP12,CASP4,CTNNB1,BAX,MYBL2,AIFM1,HTR2A,CDK5,MCL1,NQO1,CCL3,CDK5R1,ATF4,TRAF7,FASLG,DDIT3,FBXW7,MIR98,UBE2M,PRNP,BACE1 |
| 2.645e-03 | -5.93 | Cytokine-cytokine receptor interaction | KEGG pathways | hsa04060 | 270 | 115 | 7161 | 2463 |
CXCR4,CCL11,TGFBR2,FAS,IL2RG,IFNB1,TNFRSF9,CCL5,CXCR3,IL1A,IL10,CD40,TNFSF18,CCL25,CCL17,GH1,IL1RAP,CXCL1,IFNG,CXCL10,XCL1,EDA2R,CSF2,TGFB2,CD40LG,IL13,CCR3,CCL4L1,IFNA2,IFNK,LTA,IL12A,CCR7,IL2,CCL19,CXCL3,IL15,IL7,VEGFC,CCL2,CCL23,CXCL14,TNF,BMPR2,IFNA13,IL1B,PRL,IL3,CX3CR1,CXCR1,TGFB3,CCR4,CCR2,CCL21,FASLG,IL12B,CCL18,BMPR1B,TNFSF8,IFNA10,CCL20,CXCL9,TNFSF10,CCL1,TNFSF15,CCL24,CCL8,CCR1,CCL28,ACKR3,IL6,CXCL13,IL15RA,TNFRSF1B,MET,CCL3,TNFSF13,GHR,ACVR1B,LEPR,PLEKHO2,CX3CL1,CXCL8,CCR6,IL20RB,OSM,VEGFA,IL6ST,IL23A,IL1R2,IL5,TNFSF12,TNFRSF14,LTBR,KIT,CCR5,CXCL12,EPO,BMPR1A,IL21,IL22,IL17F,IL2RB,CNTFR,IL4,IL2RA,CXCL11,LEP,CXCR6,CCL27,IFNAR1,IL18,LTB,ACVR1,IFNGR1 |
| 2.645e-03 | -5.93 | Cytokine-cytokine receptor interaction | KEGG pathways | ko04060 | 270 | 115 | 7161 | 2463 |
PRL,IL1B,IFNA13,BMPR2,TNF,CXCL14,CCL23,CCL2,VEGFC,IL7,IL15,CXCL3,BMPR1B,CCL18,IL12B,CCL21,FASLG,CCR2,CCR4,TGFB3,CXCR1,CX3CR1,IL3,IL1RAP,GH1,CCL17,CCL25,TNFSF18,CD40,IL10,IL1A,CXCR3,CCL5,TNFRSF9,IFNB1,IL2RG,FAS,CCL11,CXCR4,TGFBR2,CCL19,CCR7,IL12A,IL2,LTA,IFNK,IFNA2,CCL4L1,IL13,CCR3,CD40LG,CSF2,TGFB2,EDA2R,XCL1,CXCL10,IFNG,CXCL1,CNTFR,IL2RB,IL17F,IL22,IL21,BMPR1A,EPO,CXCL12,KIT,CCR5,LTBR,TNFRSF14,TNFSF12,IFNGR1,ACVR1,LTB,IL18,IFNAR1,CCL27,CXCR6,LEP,CXCL11,IL2RA,IL4,TNFRSF1B,CXCL13,IL15RA,IL6,CCL28,ACKR3,CCR1,CCL8,CCL24,TNFSF15,CCL1,TNFSF10,CXCL9,CCL20,IFNA10,TNFSF8,IL1R2,IL5,IL23A,IL6ST,VEGFA,OSM,CXCL8,CCR6,IL20RB,CX3CL1,PLEKHO2,LEPR,ACVR1B,GHR,TNFSF13,MET,CCL3 |
| 2.652e-03 | -5.93 | trans-synaptic signaling | biological process | GO:0099537 | 431 | 154 | 18204 | 5365 |
HTR1A,MECP2,ACHE,TPBG,GABRA2,INSYN1,MEF2C,SYN3,CHRNA7,CHRNB2,EZH2,SNAPIN,SLC32A1,DNAJC5,CPLX1,GABRB2,NQO1,SNCG,INSYN2A,PSEN1,PCDHB13,GJC1,SV2B,GRIA2,CBLN2,LIN7C,OPRK1,NTRK2,CLSTN3,SYT4,GLRA1,HTR5A,RIMS3,NLGN1,HCRT,PAFAH1B1,SDCBP,CACNB2,PPFIA3,TAC1,NPBWR1,FCHSD2,PNOC,SYT2,MPZ,CNP,GABRA1,SLC6A2,SNCB,SLITRK5,CHRM4,STAC3,LARGE1,CPLX3,HTR2A,DAG1,ADORA1,VDAC1,HTR1F,GRIK1,GABBR1,EXT1,SST,COMT,PDLIM4,SNAP25,FGF12,DLG4,SLC1A3,PMP22,GRM1,CHRM5,HOMER1,SNAP29,GPR176,GLRA2,RIT2,TMOD2,GAD2,CHRM1,VAMP2,SYPL1,PTEN,STXBP1,USP14,PLP1,GRID1,NPY5R,ASIC2,CHRM3,CPLX2,CACNB4,PRKCE,DRD1,GSK3A,GUCY1B1,KCNJ8,KCNIP2,TNR,NLGN2,GLRB,SNAP23,INSYN2B,UTS2,GHRL,GRIA1,SCN2B,PDYN,CARTPT,RIC3,DLG3,DLG1,LYNX1,RAB3A,CNR1,NPTX1,SLC29A1,GRM2,VPS54,NAPA,CBLN1,CACNB3,NSG1,PPT1,HRH2,RIMS4,SLC6A3,KCNMB1,HRH3,CTNNB1,SLC1A1,CRHBP,NPR2,GABRG2,RAP1A,ASIC1,DBH,SLC1A2,KCND2,AKT1,STX1A,CDK5,GABRB3,SLC6A1,NPY,PPP3CA,WNT7A,STX11,PLG,DRD3,IL1RAP,CHRDL1,GABARAP,LIN7B |
| 2.660e-03 | -5.93 | AASS (aminoadipate-semialdehyde synthase) | protein interactions | 10157 | 70 | 31 | 19454 | 5460 |
AUH,MYC,FAM174A,SFN,CUL3,YWHAG,YWHAH,CTNNB1,RHOG,YWHAZ,HSP90AA1,YWHAB,CCNF,SSBP1,VDAC2,COX4I1,GATD3,APEX1,HSP90AB1,ATP5PB,CDC42,RPA2,PDHA1,HSPD1,RPA3,EXD2,HADHA,COX8A,HSCB,ARHGEF39,IMMP2L |
| 2.661e-03 | -5.93 | GST_C | pfam domains | PF00043 | 17 | 11 | 17795 | 5224 |
GSTA1,GSTT2B,GSTM3,EEF1E1,GSTM4,MARS1,GSTM2,GSTT1,EEF1G,GSTM5,GSTA2 |
| 2.663e-03 | -5.93 | CHTOP (chromatin target of PRMT1) | protein interactions | 26097 | 201 | 75 | 19454 | 5460 |
PELP1,DLST,ZNF330,EIF4A3,FGFBP1,GSK3A,PRMT5,PTEN,FBXO22,RPGRIP1L,ESR2,SRPK2,ERH,MYC,MORF4L1,SFN,BTF3,PPP1CC,SNRPB,SPOP,FYTTD1,TDP1,UBE2H,RPA3,DDX39B,SNRPA,HSPA8,RNF113A,EP300,HMGB1,FBXW7,AATF,SF3A1,WDR77,ATG16L1,ZC3H14,CCND1,CDK1,RPA2,APOBEC3C,HEXIM1,SCLT1,THOC2,TOP1,THOC1,MOV10,WWP2,EMC4,HNRNPA1,DDRGK1,AGR2,SNRNP70,BRD3,MAP4,MAGOH,RBM3,ZC3H11A,POC1B,HSD17B10,H3C1,CHCHD2,VDAC1,VRK1,MEPCE,SMN1,SSRP1,RAF1,B3GNT2,ZNF263,SOX2,DDX39A,LBR,AURKAIP1,EZH2,PDHA1 |
| 2.672e-03 | -5.93 | IRS-mediated signalling | REACTOME pathways | R-HSA-112399 | 294 | 115 | 10285 | 3229 |
SPTBN1,PPP5C,PSME1,ANGPT1,PSMD7,FGF17,PSMD14,PTPN11,STK11,UBB,PPP2R1A,PSMD3,PSMB7,JAK2,PIK3R1,PSMB1,PSMB5,PSMA3,PSMC4,PSMA4,PSMB11,FGFR1,IL2,PSMC5,PSMB10,PSMB6,PSMA2,DLG4,RHEB,CSK,BRAP,FGF3,PSME2,PSMD6,HBEGF,PSMB9,IL2RA,SPRED2,MAP3K11,RRAGB,DUSP10,NEFL,CAB39,CSF2,LAMTOR1,JAK1,FGF7,PSMD12,AKT2,EIF4B,RRAGA,SHC3,RAP1A,FRS3,PSMD10,SRC,DUSP9,FGF10,RAP1B,MAP2K1,KRAS,FGF22,UBA52,WDR83,RAF1,IL2RG,PIK3R2,YWHAB,DUSP6,FGF1,PPP2R5A,STRADB,MET,PAQR3,FGF23,PSMA5,SPTAN1,PPP2R5E,TLR9,EIF4E,PEBP1,PSMB3,SHC1,RASGRP3,PSMB4,SEM1,PRKAB1,DUSP1,PSMC3,PSMA1,RPS27A,IL3,PHB1,PSMD4,SPRED1,FGF16,IL2RB,LAMTOR3,CAMK2G,VWF,PSMC1,CUL3,PRKAG1,KIT,LAMTOR2,PPP2CB,HRAS,GAB1,IL5,PSMD1,PSMB2,PIK3CA,AKT1,PSMA6,PEA15 |
| 2.676e-03 | -5.92 | synapse organization | biological process | GO:0050808 | 333 | 122 | 18204 | 5365 |
MTMR2,HSPA8,C1QL3,IGSF21,LAMB2,LARGE1,SLC25A46,PRNP,SNTA1,C1QL1,HOMER1,DLG4,GPC4,C1QL2,LRRTM1,SDCBP,PPFIA3,ADD2,CACNB2,LRRC4,NLGN1,CBLN3,EPHA4,ZC4H2,ARF1,STAU1,IGF1R,SNCB,GABRA1,GNPAT,PCDH17,CDC42,SNCG,GABRB2,OPHN1,NOS1AP,NPTN,CLSTN3,CBLN2,PCDHB13,CAP2,RAB39B,PSEN1,ELFN1,GABRA2,ACHE,ADGRL3,CNTN2,SLITRK1,MECP2,GPM6A,SNAPIN,GPHN,CHRNA7,EFNA5,PRRT1,DRP2,LRFN3,GJA10,SLC6A1,WNT7A,WASL,GABRB3,PTK7,NTNG2,C1QC,CDK5,DKK1,HDAC6,STK38,CHRDL1,WASF3,IL1RAP,ACTB,PPFIA2,CACNB3,CX3CL1,TMEM108,MAP1B,GABRG2,SLITRK2,RAB29,CX3CR1,CTNNB1,SLC1A1,CNTNAP1,LRRTM2,GRIA1,GHRL,NEFL,CD2AP,GLRB,FLRT3,TNR,NLGN2,STK38L,PICK1,CBLN1,PPFIBP1,INA,ARF6,CRKL,NPTX1,DLG1,LHFPL4,RER1,PTEN,NRP1,CBLN4,SYBU,CACNB4,KCNJ8,DRD1,ACTL9,ASIC2,L1CAM,CTTN,FGF13,RAP1B,TUBA1A,LRRC4B,ZNF365 |
| 2.677e-03 | -5.92 | Smad3 (SMAD family member 3) | protein interactions | 17127 | 40 | 20 | 19454 | 5460 |
SLC39A10,STX18,SMAD3,ROCK1,SMURF1,GMDS,PRCP,DHX16,TAF7,UBL4A,ANXA7,LEMD3,POLR2G,SMAD2,EIF4B,GDI2,WWP1,SMAD4,ASCC1,P3H1 |
| 2.677e-03 | -5.92 | CCL21 (C-C motif chemokine ligand 21) | protein interactions | 6366 | 40 | 20 | 19454 | 5460 |
CCL17,CXCL10,CCR7,CXCL11,CCL23,CXCL9,HNRNPA2B1,CXCL14,SMARCB1,KLHL26,CXCL13,TMEM107,CCL5,CCL28,KLHL22,CTSD,CXCL12,PYCARD,CCL24,XCL1 |
| 2.677e-03 | -5.92 | PTRHD1 (peptidyl-tRNA hydrolase domain containing 1) | protein interactions | 391356 | 40 | 20 | 19454 | 5460 |
TXN,UBE2L3,NFKBIA,S100A6,HINT1,FAHD1,TSR2,PRDX6,COA4,IDH2,NUDT19,P2RY12,AK2,MSRB3,SPR,MOV10,LYPLA1,LYPLAL1,AK3,JUN |
| 2.690e-03 | -5.92 | HYDIN (HYDIN axonemal central pair apparatus protein) | protein interactions | 54768 | 11 | 8 | 19454 | 5460 |
TP53,CUL3,ERRFI1,PDIA3,CSK,FBXO22,AGR2,EZH2 |
| 2.690e-03 | -5.92 | CXCR3 (C-X-C motif chemokine receptor 3) | protein interactions | 2833 | 11 | 8 | 19454 | 5460 |
FATE1,CXCL13,TMEM14A,CXCR3,CXCL10,C2CD2L,CXCL9,CXCL11 |
| 2.690e-03 | -5.92 | BNC2 (basonuclin zinc finger protein 2) | protein interactions | 54796 | 11 | 8 | 19454 | 5460 |
CHCHD2,IRF6,FOXP4,VIRMA,FOXP2,FOXP1,TP53,RB1 |
| 2.692e-03 | -5.92 | RPP38 (ribonuclease P/MRP subunit p38) | protein interactions | 10557 | 90 | 38 | 19454 | 5460 |
RPP25L,SNRNP40,RPP25,ESR2,SURF6,CPSF1,ZNF330,PSMB4,PSMB5,POP7,PSMA6,PTEN,PSMB1,DDX23,CDC23,MYC,PSMA4,GTF2E1,DDRGK1,PSMA1,NPM3,PSMA5,STAU1,RPP14,SIAE,PCGF6,RPL31,PALM2AKAP2,SNAPC1,RNF113A,SQSTM1,MOB3C,RAF1,TOR1AIP2,NCSTN,RPP21,ASPM,POP5 |
| 2.692e-03 | -5.92 | SQOR (sulfide quinone oxidoreductase) | protein interactions | 58472 | 90 | 38 | 19454 | 5460 |
CDPF1,SMAD3,UQCRC2,CPT2,ATP5F1B,MATR3,RAMP3,CUL3,CTSD,RAB32,MOV10,MYC,HMOX2,NONO,YWHAZ,TUBG1,POR,SMAD2,PML,RPA3,COX17,FBXW7,TRIM37,RAF1,CFTR,ST7,NCSTN,ISG15,UQCRC1,SAMM50,STX17,EZH2,VAPB,RPA2,NUDT19,OTULIN,HAUS2,SLC25A3 |
| 2.692e-03 | -5.92 | TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor) | protein interactions | 6886 | 90 | 38 | 19454 | 5460 |
SSBP3,RARS1,ID4,TNPO2,SSBP2,SPTBN1,MARS1,RPS13,SATB1,RBBP7,KDM1A,DLAT,EP300,TAL2,PPM1G,DRG1,SP1,NCAPG2,SUV39H1,RUNX1,PSMD1,LDB1,LMO2,CREBBP,DBT,PRKCQ,CDK9,RPL13A,TOP1,RB1,ZHX1,TRIM27,HEXIM2,PSMA6,SIN3A,SSBP1,ELSPBP1,STUB1 |
| 2.692e-03 | -5.92 | RBL2 (RB transcriptional corepressor like 2) | protein interactions | 5934 | 90 | 38 | 19454 | 5460 |
PHB1,CDK6,MYBL2,RBBP4,TOP1,DYRK1A,BTG3,CDK9,CITED1,MDM2,CCNB1,DYRK1B,CSK,SUV39H1,PCBD1,CSNK2A1,LBX1,BRCA1,TFDP2,RBBP8,IRF3,RINT1,PML,SKP1,CCND3,AATF,CDK4,E2F4,CCND1,RBBP9,RAF1,CCNA2,CDKN1A,XBP1,CTBP1,EZH2,BIRC5,HBP1 |
| 2.692e-03 | -5.92 | TMEM126A (transmembrane protein 126A) | protein interactions | 84233 | 90 | 38 | 19454 | 5460 |
RHOB,ESYT1,LRRC73,KRBOX4,BAG3,TNFSF18,RHOJ,ARMC6,ESR2,PARL,RAMP3,APLNR,COX4I1,DUSP6,SSBP1,CCNF,SLC1A1,PCBP4,EDNRA,RPA2,TMEM182,SLC25A3,PARD6A,CDK4,APOO,EYA3,DNAJC30,LPAR1,CHCHD2,SRSF2,TSPAN15,NDUFA4,SFXN1,RPA3,LPAR2,EWSR1,TACR1,VIPR1 |
| 2.696e-03 | -5.92 | NUP153 (nucleoporin 153) | protein interactions | 9972 | 198 | 74 | 19454 | 5460 |
KPNA2,NUP42,NUP107,SREK1IP1,HAPSTR1,HDAC11,GLE1,RANBP1,NUP37,TNPO2,NUP153,SUMO2,FZR1,NOP58,NUP35,CETN2,EGLN3,MGME1,EEF1B2,KLHL7,SMAD3,CTDSPL2,XPO5,PTGER4,KPNA1,DPY30,GRSF1,IFI16,XPO1,PPM1D,YTHDF1,B9D2,TMEM209,G3BP2,SIRT7,BAP1,RPA3,MEA1,NUP50,RNF113A,CLK1,IER2,RPA2,LMNA,EIF4B,SUMO1,NUP62,DYRK1A,VIRMA,ESR2,RAN,NFKBIA,LMBR1L,PSPC1,CCNF,SEC61B,UBE2I,ARPP19,FBXW11,BICD2,TDP1,BRCA1,LMNB1,SPOP,MAPRE1,XPOT,SMAD2,CUL3,MYC,KPNA6,MCM4,PPP1CC,DEPDC1B,SMARCE1 |
| 2.696e-03 | -5.92 | CAMK2D (calcium/calmodulin dependent protein kinase II delta) | protein interactions | 817 | 198 | 74 | 19454 | 5460 |
UBE2H,DTL,HSP90AA1,FKBP1B,BRCA1,SKAP2,KANSL3,FAM163B,MRM2,CUL3,MYC,AKT1,TNPO3,DYRK1A,ESR2,STAT1,SSH3,TMOD3,SENP5,PHKB,UBE2I,MTG1,CAMK2N1,LMBR1L,CCNF,HAUS2,SSR1,RPA2,CDKN1A,ELP3,TIRAP,TSHR,PIP5K1A,ATG16L1,GTF2H4,WASF3,CXXC1,ARMCX5,STAU1,FXR2,TSR3,DNAL4,HSPA8,BAP1,RPA3,TIAM1,H2AC4,ARL2BP,TUBG1,IFI16,ZBTB2,RBM42,EGLN3,TRMT61A,PRNP,CGAS,ARHGAP25,SH2D1A,PPP2CB,RCHY1,RBPJ,SMARCB1,POLR2C,PRKAG1,AGPAT5,TNPO2,ACTR1A,DDX39A,MRPL11,RPS4X,CAMK2G,MYO1B,HNMT,BCKDK |
| 2.696e-03 | -5.92 | XBP1 (X-box binding protein 1) | protein interactions | 7494 | 48 | 23 | 19454 | 5460 |
XBP1,UBE2V1,CREBZF,HM13,NFYB,PIK3R1,NFYA,POU5F1,H1-10,FAS,UBE2I,DERL1,FOS,PSMA6,FUBP3,SRSF1,TRIP4,APEX1,RIGI,MDM2,PRNP,FBXW7,PSMA5 |
| 2.696e-03 | -5.92 | TLR3 (toll like receptor 3) | protein interactions | 7098 | 48 | 23 | 19454 | 5460 |
CFTR,CD14,KCND3,TBK1,SYK,TAB2,TLR3,BIRC2,SQSTM1,MYD88,TICAM1,TICAM2,CNOT6L,RNF115,RBCK1,TOLLIP,LRRC40,CSK,PIK3R1,TRAF6,KCND2,MAP2K6,VIRMA |
| 2.696e-03 | -5.92 | TTLL5 (tubulin tyrosine ligase like 5) | protein interactions | 23093 | 48 | 23 | 19454 | 5460 |
CREB3,NDC80,DNAJC7,MED4,PTTG1,FBLN5,KRT8,CSRNP1,VIRMA,MVD,ATG16L1,TP53,CDKN1A,PNMA2,HSPD1,PSME1,HSPA8,THBS3,TRIM37,TRIM52,PTGES3,FTL,FKBP8 |
| 2.696e-03 | -5.92 | AEBP2 (AE binding protein 2) | protein interactions | 121536 | 48 | 23 | 19454 | 5460 |
RBBP7,PHB2,TRIM63,LDOC1,PHF1,FTL,PICK1,EZH2,THAP1,RALYL,TTC9C,RBBP4,EZH1,TNFRSF1B,EED,LDLR,EPOP,FBXW11,LACRT,H1-1,CSK,MDFI,RPL39 |
| 2.696e-03 | -5.92 | Snu13 (SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)) | protein interactions | 20826 | 48 | 23 | 19454 | 5460 |
MOV10,SNRPB,KPNA6,ZNHIT3,KPNA1,ZNHIT6,SNRPD1,SNRPD2,NOP58,SNRPD3,DKC1,DHX15,WRAP53,SNRPE,SART3,PABPC1,RUVBL2,DHX9,HNRNPF,KPNA2,RUVBL1,NHP2,COIL |
| 2.696e-03 | -5.92 | MYSM1 (Myb like, SWIRM and MPN domains 1) | protein interactions | 114803 | 48 | 23 | 19454 | 5460 |
ZNF330,MACROH2A1,PRMT5,SNRNP40,AR,PPIB,RFC5,H2AC4,TCEAL9,DICER1,RFC4,HELLS,NUP50,PCNA,MCMBP,STK38,H3C1,WDR77,EEF1A1,H2AX,LMNA,CBX3,CDK8 |
| 2.696e-03 | -5.92 | GTF2H3 (general transcription factor IIH subunit 3) | protein interactions | 2967 | 48 | 23 | 19454 | 5460 |
CETN2,GTF2H2,GTF2F1,CDC7,BRD3,HMGA1,ERCC3,AR,GTF2E1,H2BC9,STAU1,THRAP3,KRAS,MNAT1,RPA3,CLK1,RPA2,RNF8,GTF2H5,RARS1,GTF2H4,CDK7,PRMT2 |
| 2.701e-03 | -5.91 | P-loop containing nucleotide triphosphate hydrolases | gene3d domains | 3.40.50.300 | 757 | 251 | 14470 | 4137 |
RAB3A,SRPRB,RFC2,DLG1,CASK,MCM3,RASL12,GNAQ,KTI12,RUVBL2,RAB4A,DCK,RHOBTB3,GAL3ST1,ATP5F1A,MPP1,SMC4,CMSS1,CLP1,UCKL1,RIGI,RAP1A,RAB35,DDX4,NKIRAS1,RAB29,AGAP1,DAPK1,RAB30,DDX50,DDX1,DIRAS1,DIRAS2,IFT22,TOR1B,SRPRA,GNA11,NLRP1,HRAS,RRAS2,CACNB2,RAB31,PSMC5,TRIM23,RASD1,UCK2,MFN1,RASL10B,GTPBP1,RAP2B,RHOBTB1,RAB6B,MCM8,PSMC1,EHD3,ABCC2,RFC3,MOV10,RAB8B,DDX23,GAL3ST4,WSCD1,ARF6,MCM4,CACNB4,ARF4,MMAA,ARF1,DNAJC27,RAP2A,ABCF1,DTYMK,KRAS,RHOG,RAB3B,ELP6,RAB6A,HS2ST1,NLRP3,ARL5B,AK5,DCAKD,ABCB9,IFIH1,RAB14,RAB3C,VPS4A,RHOU,UCK1,RABL2B,ERAS,RAB1B,RAB33A,RIT1,RALA,RAB18,MRAS,RND2,RAB39B,MSH6,SHPRH,RAC2,RIT2,NMRK1,DDX39B,EEF2,CHST2,SULT1A3,CMPK1,NLRP2,RRAGB,PSMC4,GUK1,NKIRAS2,GNAO1,SRP54,PALS2,EIF5B,ABCG2,RHOJ,RAB11A,RALB,NTPCR,RHEB,HELLS,EHD4,ARL10,NOA1,RRAGA,SEPTIN7,NUBP2,RAB13,EIF4A3,DDX46,ATAD1,GFM1,RAB2A,GNAI3,DLG4,RHOH,GIMAP4,ORC5,HS3ST1,DHX38,RFC4,GTPBP8,ATP6V1A,ABCC5,ATL1,DLG3,GTPBP2,RAB1A,CLPB,RAP1B,MTG2,RAB5C,CHST1,RAB37,SMG9,DIRAS3,RABL3,ARL6,UST,GNA14,SMARCA5,GNAI2,AK2,RAB11B,NDST1,RASL10A,MX1,GNAZ,MTG1,TUFM,DDX42,RAB19,RAB27A,CACNB3,NLRP6,CNP,RAB5A,VPS4B,DHX16,RAB32,EEF1A1,CFTR,RAN,EHD1,DNM2,RND3,RUVBL1,NDST3,ABCE1,ERCC3,NLRP9,GNL1,ABCB1,DICER1,RFC5,DDX39A,TWNK,HS3ST5,EIF4A2,SAR1B,ATP5F1B,ARL15,CENPM,MCM6,GFM2,RAB33B,HS3ST3A1,ARL4D,RAB9B,RAP2C,RERG,PFKFB2,AGAP2,RAB3D,DHX9,RHOB,MX2,TOR3A,RAB23,CLPX,GIMAP2,UTP25,PAPSS2,RAB22A,SULT1B1,BCS1L,RAB9A,ARL11,ARHGAP5,RAB40AL,TOR4A,GPN2,SEPTIN6,CDC42,AK3,RASL11A,THNSL1,PSMC3,DHX15,OLA1,KATNAL1,ARL4A,TPST1,TOR2A,RAB28,DDX5,CHST7 |
| 2.707e-03 | -5.91 | PLK1 (polo like kinase 1) | protein interactions | 5347 | 494 | 167 | 19454 | 5460 |
ANAPC2,PSMB6,APEX1,USP16,TUBB,FBXO22,MCM3,MCM4,USP13,MYC,PSMA4,CUL2,CFAP20,CUL3,RIT1,LAMTOR1,CIRBP,RBBP8,BRCA1,RHOB,RABAC1,PSMA3,JADE1,STK26,AKAP1,LCA5,COIL,FTL,SRI,NEK7,LMO4,TANK,PSMB3,PSRC1,CSNK1A1,CTBP1,PSMB7,IFTAP,EED,KRT8,RAB35,DNM2,PSMB5,FEZ1,PSMB4,CNTROB,EGLN3,STK3,DBR1,RGCC,DNAJB9,YWHAG,ATG7,YWHAH,ACTL6B,CTNNB1,DYRK1B,BABAM1,NDC80,TRIM8,PEX3,DCAF11,MED4,AHSA1,DICER1,BCL2L1,IKBKB,ARHGAP5,ZC3H7A,GTF3C3,MCM6,DCTPP1,AHCYL1,KRAS,PSMA1,HNRNPF,PSMA2,TUBA1A,PPP2R1A,ASPM,KIF2A,SNCB,RNF126,SKA3,STIM1,PPID,CSNK2B,CALML5,UBE2I,PTEN,STUB1,CCNF,PSMA6,CDC20,CEP97,DYRK1A,RPP25L,PTHLH,ATP5F1A,NCAPG2,PPP1CC,RACGAP1,TUFM,PSMB2,AKT1,CDC16,CCNB1,MAPRE1,MECP2,IVNS1ABP,BICD2,HMCES,FAM53C,MAVS,DVL2,RPA3,CLU,FBXW7,OIP5,GTF3C4,TPT1,SUMO1,PITPNA,TRIM36,KLF4,PAK5,RPA2,IDH2,LDLR,PSMB1,TRAK2,WDCP,PTPN1,MDM2,CDC5L,FZR1,ARF6,COPS5,HDAC6,GPRASP2,KLHL22,KLHL9,SLC25A46,USP15,TOPBP1,TUBG1,CRBN,NOS1AP,RPL3,IDH1,MAP1B,PPP1R12A,LTBR,RAB1A,CACNG3,PSMA5,AKAP12,SCML1,KBTBD4,TBK1,ANGPT1,CDK4,TP53,TOPORS,CAPN2,MAD2L1BP,TP53I3 |
| 2.710e-03 | -5.91 | positive regulation of protein modification by small protein conjugation or removal | biological process | GO:1903322 | 134 | 55 | 18204 | 5365 |
SKP1,PIAS1,TOPORS,ARRDC3,RPS2,UBE2N,UBE2D1,UBE2S,CDKN1B,CUL3,HDAC3,HSPA5,TOLLIP,NDFIP1,TRAF6,WBP1L,CRY1,GSK3A,CDK5RAP3,DCUN1D3,DERL1,DCUN1D1,PTEN,TICAM1,PHF23,CAV1,PSMD10,NSMCE3,KDM1A,NMI,RBCK1,HUWE1,GABARAP,FBXW7,TANK,PELI1,STUB1,UBE2V2,PTPN22,FAM107A,UBE2V1,RWDD3,ANGPT1,BCL10,NOP53,RCHY1,UBE2L3,BIRC2,UBB,FZR1,CDC20,DCUN1D5,MAGEC2,MUL1,UBE3A |
| 2.713e-03 | -5.91 | Cell cycle | KEGG pathways | ko04110 | 124 | 58 | 7161 | 2463 |
CDC20,CDKN1A,CDK1,FZR1,CDK4,CDK7,MAD2L1,CDC7,CCND3,CDC16,ZBTB17,YWHAG,CDKN2C,PCNA,YWHAB,SMAD3,E2F4,RAD21,SFN,CDC26,TGFB3,CCND1,CCNA2,BUB3,PTTG1,MDM2,CREBBP,MCM4,ORC5,MYC,CCNB1,SKP1,CDC23,ANAPC2,TFDP2,GADD45G,GADD45B,SMAD2,ANAPC11,CDKN1B,MAD2L2,YWHAH,CCNH,ORC6,ANAPC13,YWHAZ,TP53,GADD45A,TGFB2,CDK6,RB1,MCM6,MCM3,SMAD4,EP300,CDKN2D,ANAPC4,WEE2 |
| 2.713e-03 | -5.91 | Cell cycle | KEGG pathways | hsa04110 | 124 | 58 | 7161 | 2463 |
PTTG1,CCNA2,CCND1,BUB3,MCM4,CREBBP,MDM2,ORC5,E2F4,SMAD3,RAD21,TGFB3,CDC26,SFN,CDC7,ZBTB17,CDC16,CCND3,YWHAB,PCNA,YWHAG,CDKN2C,CDC20,CDK1,CDKN1A,MAD2L1,CDK7,CDK4,FZR1,RB1,MCM3,MCM6,CDKN2D,SMAD4,EP300,WEE2,ANAPC4,TP53,YWHAZ,CDK6,TGFB2,GADD45A,CDKN1B,ANAPC11,SMAD2,MAD2L2,ANAPC13,ORC6,CCNH,YWHAH,SKP1,MYC,CCNB1,ANAPC2,CDC23,TFDP2,GADD45B,GADD45G |
| 2.722e-03 | -5.91 | Insulin receptor signalling cascade | REACTOME pathways | R-HSA-74751 | 297 | 116 | 10285 | 3229 |
PSME2,FGF3,HBEGF,PSMD6,IL2RA,SPRED2,PSMB9,MAP3K11,RRAGB,NEFL,DUSP10,CAB39,CSF2,FGF7,LAMTOR1,JAK1,PSMD12,EIF4B,AKT2,RRAGA,SHC3,RAP1A,PPP5C,SPTBN1,ANGPT1,PSME1,FGF17,PSMD7,PSMD14,PTPN11,STK11,PPP2R1A,UBB,PSMB7,JAK2,PSMD3,PSMB1,PIK3R1,PSMA3,PSMB5,PSMC4,PSMA4,PSMB10,IL2,PSMC5,FGFR1,PSMB11,PSMA2,PSMB6,BRAP,CSK,RHEB,DLG4,SHC1,RASGRP3,PSMB4,SEM1,DUSP1,PRKAB1,PSMC3,PSMA1,IL3,RPS27A,SPRED1,PSMD4,PHB1,FGF16,CAMK2G,LAMTOR3,IL2RB,VWF,PSMC1,CUL3,PRKAG1,IL5,HRAS,GAB1,KIT,PPP2CB,LAMTOR2,PSMB2,PSMD1,PEA15,PSMA6,AKT1,PIK3CA,PSMD10,FRS3,DUSP9,SRC,FGF10,RAP1B,KRAS,MAP2K1,WDR83,UBA52,FGF22,RAF1,IL2RG,PIK3R2,YWHAB,PPP2R5A,FGF1,GRB10,DUSP6,PAQR3,MET,STRADB,PSMA5,FGF23,EIF4E,TLR9,PPP2R5E,SPTAN1,PSMB3,PEBP1 |
| 2.740e-03 | -5.90 | protein insertion into ER membrane | biological process | GO:0045048 | 31 | 17 | 18204 | 5365 |
TRAM2,EMC6,UBL4A,EMC9,EMC8,TRAM1L1,CCDC47,SEC61A1,TRAM1,WDR83OS,EMC1,EMC10,EMC2,EMC4,SGTA,CAMLG,TMEM147 |
| 2.740e-03 | -5.90 | microglial cell activation | biological process | GO:0001774 | 31 | 17 | 18204 | 5365 |
IFNG,MIR181C,TLR3,CX3CL1,TLR2,JAK2,TNF,TYROBP,CLU,TLR9,IL13,IFNGR1,AGER,CX3CR1,KCNJ8,TLR6,AIF1 |
| 2.745e-03 | -5.90 | regulation of protein-containing complex assembly | biological process | GO:0043254 | 419 | 150 | 18204 | 5365 |
VDAC2,TNF,HAUS2,SVIP,EP300,SPTBN1,MIR144,CAPZA1,ANKRA2,RAF1,MAP1B,BAK1,TRAF2,TMOD3,ESAM,ADD1,SLAIN2,CYFIP2,BIRC2,TFRC,NCK1,RPS3,CCL24,PTPN22,STUB1,ABHD17A,SYK,CLU,HMGB1,DYRK1A,STX1A,ARFGEF1,NOP53,DKK1,RALB,TPPP,PREB,ISG15,HDAC6,TLR6,CCR7,STXBP6,VPS39,PYCARD,HCLS1,STXBP1,IL5,NCKAP1,TIRAP,TMOD2,CAND1,NR1H2,SH3GLB1,TMSB4X,PRKCE,DRG1,CTTN,RB1,RAP1B,LCP1,SUMO1,CCL21,LMO4,MET,MIR214,MIR17,RPL13A,CDC42EP2,SOX9,TPPP3,ABITRAM,FKBP4,EIF2AK2,VPS16,UBLCP1,NAPA,ARF6,CDC42EP3,MSN,DLG1,CYRIB,FCHSD2,ADD2,CAMSAP2,TP53,IFNG,LCMT1,SPTAN1,SOST,TMSB10,CLEC7A,BAX,P2RY12,FERMT2,CRYAB,PYDC2,CDC42,NEK7,VPS33A,PSRC1,CYRIA,HSPA8,CALY,SRC,CRBN,CLIP3,HSP90AA1,PTPN11,CSF2,HAX1,COTL1,CCL11,TLR4,EPS8,CDK5R1,TICAM1,TRIM11,CPTP,TPPP2,LGALS3,MKKS,WNT10B,MECP2,MTPN,SAR1B,SSH3,MAVS,ARPC2,CDC42EP4,CD36,VEGFA,CAPG,FAF1,VPS18,ARPC3,CAV3,ATAT1,CAPZA2,CDKN1B,HSPA5,PIK3R2,TMOD1,MYD88,MAPRE1,TFIP11,CXCL13,STMN2,CSNK1A1,CTNNBIP1,PTGER4 |
| 2.748e-03 | -5.90 | TGM2 (transglutaminase 2) | protein interactions | 7052 | 226 | 83 | 19454 | 5460 |
RPAP3,SLC25A5,RIGI,VTA1,PSMD12,WASL,CSE1L,SERTAD1,HNRNPF,DSTYK,UBE2V1,TMEM176A,PPP2R1A,DHX38,TP53,TMEM126A,RAF1,NUPR1,TAB2,DISC1,NHERF1,RB1,GJA1,PPP2CB,SMAD3,G6PD,TOMM70,CGAS,CCAR2,RPS10,TPM3,YWHAG,HP,PRPF19,PSMD3,MAP4,UBFD1,CBL,AGR2,PSMD7,SQSTM1,HSPA8,RFC4,HSPA5,PSMC1,ITGAV,HMGB1,SLC7A9,CFTR,PAFAH1B1,CNDP2,CYC1,ACACA,GSTP1,SH3GLB2,MMP14,MAP3K12,PAK2,PSMB7,PSMC5,PRMT5,SF3B4,TMSB4X,NFKBIA,DYRK1A,UBB,ACTB,PSMD6,TUBB,ADRM1,PSMD4,PSMD1,ATP5F1A,BTF3,LDHB,ATF4,MYC,SMAD2,YWHAZ,LACRT,BRCA1,MCM8,CKB |
| 2.760e-03 | -5.89 | RIOX2 (ribosomal oxygenase 2) | protein interactions | 84864 | 93 | 39 | 19454 | 5460 |
RPS16,FZR1,RPL35,RPL13A,PRNP,RPL19,RPL10,RPL8,SURF2,HEXIM2,MECP2,NOL12,IFI16,MYC,RIOX2,DDRGK1,HSCB,UFL1,NPM3,RPL4,STAU1,POLL,SRSF4,RPL17,LIN7C,XRCC5,TXNL1,RPL3,RBM18,RPL26L1,NOL7,PGGT1B,RPS11,MACROH2A2,RPL18,RAF1,RPL27A,NAA16,SOX21 |
| 2.760e-03 | -5.89 | FUNDC2 (FUN14 domain containing 2) | protein interactions | 65991 | 93 | 39 | 19454 | 5460 |
TMEM14B,SERPINA1,SDR16C5,ARL15,TP53I3,STOM,SEC62,NEK2,FUNDC1,FAF2,SLC16A10,MTCH2,KRAS,AKAP1,SAT1,GLUL,TMX2,BCL2L1,DNAJC7,MFSD14B,FCER1G,MFN1,SLC25A46,MZB1,USP13,CIDEB,MOV10,CRB3,FUNDC2,REEP4,GPX1,MGST3,COX20,SYT2,RETREG3,SLC66A2,RGS1,CALML5,CYB5R3 |
| 2.760e-03 | -5.89 | KIR2DL4 (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4) | protein interactions | 3805 | 93 | 39 | 19454 | 5460 |
G6PC3,LRP12,B4GALT1,STX10,LDLR,GPR89A,VAMP3,TNPO3,RHOBTB3,SLC30A5,MLF1,PTPN11,XPOT,SLC39A13,DOLK,NCR3LG1,ATP1A3,EXOC2,PIGA,FCER1G,TRAF6,YIF1A,ATP2B4,RINT1,TMED7,CERS6,YIPF3,TNPO2,FAM234A,GINM1,TIMMDC1,JMJD8,IPO8,MTCH2,SLC19A2,HGS,FAM3C,MOXD1,EXOC3 |
| 2.760e-03 | -5.89 | ARHGAP17 (Rho GTPase activating protein 17) | protein interactions | 55114 | 93 | 39 | 19454 | 5460 |
DLGAP4,CTTN,EIF3K,COMT,PSME2,SRC,CDK9,ACTB,YWHAG,YWHAH,TXNRD2,PIK3R1,MAPRE1,NLRP3,RHOB,LAMTOR1,SPOP,CKB,ARPC2,COMMD2,BAG2,RTCB,EWSR1,LSM14A,RPA3,CAPZA1,HSCB,EIF4EBP2,STXBP1,CDC42,CD2AP,DLG3,TOP3B,PARD6A,OXSR1,SH3GLB1,LSM2,NHERF1,TRIM68 |
| 2.760e-03 | -5.89 | SRSF8 (serine and arginine rich splicing factor 8) | protein interactions | 10929 | 93 | 39 | 19454 | 5460 |
YWHAG,CD81,YWHAH,ST13,TRA2A,HNRNPC,SFN,ELAVL2,MAGOH,MECP2,YWHAZ,SNRNP70,PRR3,EED,RBMX2,FOLR1,ZBTB2,ERH,SRPK2,APOBEC3D,RPL15,PABPC5,WDR83,RAF1,METTL14,LARP4B,NGB,NMRAL1,ZC3H11A,CLK1,SRSF7,SNRPA,SNIP1,NKAPD1,SRSF4,SAP18,SNRNP48,TRA2B,THRAP3 |
| 2.772e-03 | -5.89 | regulation of leukocyte apoptotic process | biological process | GO:2000106 | 89 | 39 | 18204 | 5365 |
CCL19,IL2,CCR7,MIRLET7B,TSC22D3,SELENOS,CCL21,MIF,CD3G,ORMDL3,LILRB1,BCL6,CXCL12,BCL10,PRKCQ,CD274,CCR5,PDCD1,RAG1,BAX,GPAM,ARG2,PTCRA,ST3GAL1,MIR34A,MEF2C,CCL5,IRF7,HCLS1,SLC7A11,BCL2L1,LGALS3,FOXP1,ST6GAL1,IL10,TP53,IDO1,PRELID1,SLC39A10 |
| 2.775e-03 | -5.89 | DEGS1 (delta 4-desaturase, sphingolipid 1) | protein interactions | 8560 | 59 | 27 | 19454 | 5460 |
EIF5B,PSEN1,RPA3,BSCL2,SLC16A1,CPLX2,SURF4,RPA2,LMNA,VAPB,CLEC2B,DNAJC25,LPAR6,CFTR,PYGM,APLNR,SURF6,OPRL1,KCNA2,COX4I1,GTF2F1,LAMTOR1,NCR3LG1,ESYT1,OPRM1,GPR17,UFD1 |
| 2.775e-03 | -5.89 | GCFC2 (GC-rich sequence DNA-binding factor 2) | protein interactions | 6936 | 59 | 27 | 19454 | 5460 |
RPA3,EP300,PSENEN,NPTN,UFL1,GINM1,CD2BP2,CDK8,RPA2,HDAC11,TFIP11,SNRPE,SYNCRIP,EIF4A3,SNRPA1,SNRNP40,PRNP,THOC1,APEX1,DHX15,PRPF19,CSNK2A1,SNRPB,DDX23,ECD,ELAVL2,HNRNPD |
| 2.775e-03 | -5.89 | GRPR (gastrin releasing peptide receptor) | protein interactions | 2925 | 59 | 27 | 19454 | 5460 |
GJC1,SLC19A2,TMT1B,DSTYK,LMBRD2,RAB4A,PTRH2,DPH6,RETREG2,SLC35G2,ARL5B,USP30,RAB3B,SLC6A8,RAB32,FAR2,DHRS7,MBLAC2,FITM2,MTG1,MFSD5,RAP1B,GPR89A,GNPAT,ADCK1,RAB39B,MAD2L2 |
| 2.775e-03 | -5.89 | MARVELD2 (MARVEL domain containing 2) | protein interactions | 153562 | 59 | 27 | 19454 | 5460 |
RAP2A,STK38,KRAS,STX7,TP53,DDX39A,CHMP4C,RND3,RAB35,HRAS,GJA1,RHOJ,ARF6,CAV1,VIRMA,DIRAS3,RAB11A,RAB5C,LAMP2,MOV10,RAB2A,FATE1,DNAJC5,LAMP3,RHOB,LAMTOR1,TTL |
| 2.775e-03 | -5.89 | PI4K2B (phosphatidylinositol 4-kinase type 2 beta) | protein interactions | 55300 | 59 | 27 | 19454 | 5460 |
CCT2,HSP90AA1,CD247,GMPPB,AKT1,ATG7,TUBB,TCP1,MANSC1,GFOD1,CCT7,LRRC61,NAA11,ZNF174,CRYBB3,SPINT2,CCT5,WDR5B,KBTBD4,HCST,SLC31A1,FTL,PSME1,RCCD1,CCT8,BAG2,EFNB1 |
| 2.781e-03 | -5.88 | SYPL2 (synaptophysin like 2) | protein interactions | 284612 | 20 | 12 | 19454 | 5460 |
SPPL3,KRAS,GCA,HSPA5,VAMP3,TSPAN15,NECTIN2,CYB5A,REEP6,SYNGR2,SLC38A7,SLC41A1 |
| 2.781e-03 | -5.88 | RNF183 (ring finger protein 183) | protein interactions | 138065 | 20 | 12 | 19454 | 5460 |
PTGDS,EWSR1,ACTA2,NFKBIA,UBE2K,FATE1,PTPN11,UBE2W,TAX1BP3,FBP1,KXD1,BCL2L1 |
| 2.781e-03 | -5.88 | SLC12A3 (solute carrier family 12 member 3) | protein interactions | 6559 | 20 | 12 | 19454 | 5460 |
DDRGK1,KLHL3,PDIA3,HSP90AA1,SNX5,HSPA8,STUB1,GUCY1B1,EMC1,SNX1,ACTB,SNX2 |
| 2.781e-03 | -5.88 | PSH1 (ubiquitin-protein ligase PSH1) | protein interactions | 854102 | 20 | 12 | 19454 | 5460 |
ZNF473,ASF1A,UBE2D1,UBE2H,COIL,ZBTB26,ZNF250,NFYA,CCDC106,THAP1,ZFP64,GKAP1 |
| 2.781e-03 | -5.88 | CMTR2 (cap methyltransferase 2) | protein interactions | 55783 | 20 | 12 | 19454 | 5460 |
SNRPD3,SNRPG,SNRPA,HSPD1,SNRPD2,SNRNP70,SNRPE,SNRPN,PTAR1,SNRPB,FBXO7,DDX39A |
| 2.781e-03 | -5.88 | SH3BGRL2 (SH3 domain binding glutamate rich protein like 2) | protein interactions | 83699 | 20 | 12 | 19454 | 5460 |
UBE2D1,SOX2,BTF3,CFTR,USP14,MYC,PRDX1,RAF1,ESR2,DAPK1,ACTB,PRNP |
| 2.781e-03 | -5.88 | NCR1 (natural cytotoxicity triggering receptor 1) | protein interactions | 9437 | 20 | 12 | 19454 | 5460 |
CD247,SYP,OSER1,FCER1G,CD59,GSTK1,PHF1,SEC63,TMEM229B,RHOU,GLT8D1,TMEM50B |
| 2.781e-03 | -5.88 | SERF1A (small EDRK-rich factor 1A) | protein interactions | 8293 | 20 | 12 | 19454 | 5460 |
PIK3R3,TIMMDC1,TMEM14B,MED4,ELOVL4,TMX2,REEP4,SMC4,ELOVL7,RNASEK,CRB3,APEX1 |
| 2.792e-03 | -5.88 | EPC1 (enhancer of polycomb homolog 1) | protein interactions | 80314 | 73 | 32 | 19454 | 5460 |
KPNA1,CSGALNACT1,AR,MYC,HNF1B,MORF4L1,ESR2,MEAF6,ACTB,EED,TRIM27,LDLR,H2AZ1,CHRM5,VPS72,PLAC1,E2F6,DMAP1,MED23,EZH2,KLF3,H2BC1,EGR2,ELP3,KLF12,ELF1,ACTL6A,MAX,ING5,RUVBL1,RUVBL2,RINT1 |
| 2.792e-03 | -5.88 | KIF16B (kinesin family member 16B) | protein interactions | 55614 | 73 | 32 | 19454 | 5460 |
GINS4,VPS33A,RAB4A,ATG16L1,TP53,OTULINL,GABARAPL2,KRAS,STX7,TMT1A,HSPA8,RAB9A,BAG2,RAB5A,AKAP1,LAMTOR1,RHOB,ATG9A,LAMP2,SLC25A46,RAB11A,LAMP3,DNAJC5,DNAJC1,LGALS3,VIRMA,CMTR1,HSD17B11,GJA1,KRT8,TSR2,ANAPC2 |
| 2.792e-03 | -5.88 | CBLC (Cbl proto-oncogene C) | protein interactions | 23624 | 73 | 32 | 19454 | 5460 |
UBE2L3,SRC,NCKAP1,OTUD6A,YES1,TRIM46,CDK6,UBE2I,CTTN,MGME1,STK11,EPHA2,UBE2H,UBE2D1,SHC1,MYC,AKT1,USP2,TGFB1I1,UBE2D3,CYFIP2,NF2,UBE2K,BIRC2,TERT,BAP1,MET,MAP2K3,CD2AP,TOP3B,RAF1,TP53 |
| 2.805e-03 | -5.88 | Estrone Metabolism | SMPDB pathways | SMP0030880 | 14 | 11 | 1369 | 531 |
SDF2L1,COMT,PDIA6,HSD17B1,CYP1A1,ERP29,CYP3A5,UGT1A1,PDIA2,HSPA5,PPIB |
| 2.808e-03 | -5.88 | ATRX (ATRX chromatin remodeler) | protein interactions | 546 | 248 | 90 | 19454 | 5460 |
TUBA1B,CCSER2,SPIN3,PTEN,MACROH2A1,CSNK2B,RTRAF,VIRMA,CSTF3,RPL7A,ZNF687,AKT1,DNAJC8,AR,PML,NBN,GID8,RPA3,DDX46,PSMG4,HMGB1,NUCKS1,MBD3,RPA2,COX4I1,EEF1B2,MDM2,TMPO,CSNK2A1,H2AC4,TOPBP1,CDK12,TRAPPC4,STX18,HAPSTR1,H3C1,SMN1,TP53,IL1R2,TBK1,IMP3,FNTB,ING1,ESS2,H2AX,CBX3,RAD1,PHC1,GTF2F1,ZMAT2,ZMYM2,TUBB,EIF4A2,ESR2,LRIF1,CBX5,CREBBP,MCM4,LMNB1,RBM27,SETD7,PLN,XRCC5,CFDP1,STAU1,PTN,TRA2B,ADNP,MFAP1,CCDC71,BRD9,SUMO2,HNRNPL,DBR1,BTF3L4,HNRNPD,MORC2,PCNA,ASF1A,ZNF592,PTPN4,PSMA2,ZBED1,SSRP1,MCM6,SUPT5H,NUDCD3,EZH2,SKA3,MTA2 |
| 2.808e-03 | -5.88 | ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) | protein interactions | 25 | 248 | 90 | 19454 | 5460 |
FOS,DVL2,INPPL1,MAVS,TERT,SQSTM1,DDX5,EP300,HSPA8,PIK3R2,EEF1G,SPR,CDKN1A,ZDHHC16,GTF3C4,PAK2,CDK1,RTF2,RAN,CTTN,NFKBIA,STUB1,CREB1,UBASH3B,BST2,GTF2F1,AP2M1,DAPK1,GPX1,PSMD4,SRC,NCKAP1,VIRMA,SRPK2,JAK2,GRB10,SUB1,PSMA4,SFN,AR,FBXO7,ANAPC15,YWHAZ,BRCA1,PFDN4,AP2A1,HSP90AA1,PLSCR1,HSPD1,EWSR1,CDK5,PCNA,JAK1,SOS2,HSPE1,HUWE1,KIT,PTGES3,TP53,ERRFI1,TOP3B,NCSTN,SOCS3,JUN,CRKL,GRAP2,PTPN1,RPLP1,RB1,SPTAN1,ANKRA2,TMPO,MDM2,PIK3R1,PRDX1,CTNNB1,STK4,YWHAG,XPO1,YWHAH,SHC1,TRAF6,NCK1,PPM1B,DRG1,YWHAB,TOPBP1,BCL2L1,CDKN1B,CBL |
| 2.809e-03 | -5.87 | NAGS (N-acetylglutamate synthase) | protein interactions | 162417 | 9 | 7 | 19454 | 5460 |
DDX39A,TUBA1A,TUSC2,CCT2,KRAS,TCP11L1,SAV1 |
| 2.809e-03 | -5.87 | CLHC1 (clathrin heavy chain linker domain containing 1) | protein interactions | 130162 | 9 | 7 | 19454 | 5460 |
LMO2,MOV10,PIK3R1,DDX39A,FBXO7,SGF29,PRNP |
| 2.809e-03 | -5.87 | NKX3-2 (NK3 homeobox 2) | protein interactions | 579 | 9 | 7 | 19454 | 5460 |
DDX39A,SMAD1,SMAD4,RBBP7,SIN3A,SPPL3,RBBP4 |
| 2.809e-03 | -5.87 | CFAP100 (cilia and flagella associated protein 100) | protein interactions | 348807 | 9 | 7 | 19454 | 5460 |
RIGI,GRM2,TRIM54,KDM1A,SUV39H1,H2BC9,RHOU |
| 2.809e-03 | -5.87 | ZNF500 (zinc finger protein 500) | protein interactions | 26048 | 9 | 7 | 19454 | 5460 |
PHF1,SPPL3,PRNP,HEXIM2,ZNF397,TOP3B,ZNF174 |
| 2.809e-03 | -5.87 | TMCO5A (transmembrane and coiled-coil domains 5A) | protein interactions | 145942 | 9 | 7 | 19454 | 5460 |
WDR12,TMEM60,TSPAN18,CSK,BET1,VAMP5,GOSR2 |
| 2.809e-03 | -5.87 | C20orf141 (chromosome 20 open reading frame 141) | protein interactions | 128653 | 9 | 7 | 19454 | 5460 |
ZDHHC17,TNNC2,FUNDC2,REEP6,LMNA,ENDOD1,IL17F |
| 2.809e-03 | -5.87 | KCNH5 (potassium voltage-gated channel subfamily H member 5) | protein interactions | 27133 | 9 | 7 | 19454 | 5460 |
TUBA1B,CSK,KCNH1,HSPA8,TUBB,HNRNPL,TUBB4B |
| 2.809e-03 | -5.87 | DENND4B (DENN domain containing 4B) | protein interactions | 9909 | 9 | 7 | 19454 | 5460 |
RIGI,PLEKHJ1,PRNP,ST7,ZMAT5,OTULINL,CNPY3 |
| 2.809e-03 | -5.87 | SULT1C3 (sulfotransferase family 1C member 3) | protein interactions | 442038 | 9 | 7 | 19454 | 5460 |
TMOD2,CAPZA1,CSE1L,PPP1R2,KRAS,ATP6V1A,SULT1A3 |
| 2.809e-03 | -5.87 | Ubc (ubiquitin C) | protein interactions | 50522 | 9 | 7 | 19454 | 5460 |
CRYAB,SOST,TGFBR2,MYC,STUB1,CFTR,SQSTM1 |
| 2.809e-03 | -5.87 | IFI27 (interferon alpha inducible protein 27) | protein interactions | 3429 | 9 | 7 | 19454 | 5460 |
APOC2,TRIM27,TRIM21,APOC4,CSK,CDK4,CCND1 |
| 2.814e-03 | -5.87 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | REACTOME pathways | R-HSA-6781827 | 79 | 37 | 10285 | 3229 |
POLR2G,POLE3,POLR2F,PCNA,TCEA1,RFC4,UBB,COPS2,RPS27A,GTF2H2,POLR2D,UBA52,COPS4,GTF2H5,POLR2L,RFC5,CDK7,RPA3,RFC3,POLR2B,EP300,MNAT1,LIG3,POLR2C,CCNH,GTF2H4,PRPF19,COPS7A,RPA2,POLD2,COPS7B,POLR2I,COPS5,POLD4,RFC2,ERCC3,POLE4 |
| 2.821e-03 | -5.87 | cellular response to leukemia inhibitory factor | biological process | GO:1990830 | 103 | 44 | 18204 | 5365 |
MIR342,RPS16,MYBL2,EIF4A2,ILDR1,HELLS,MIR493,XRCC5,FZD4,MIR324,INA,CACYBP,PML,LRAT,MIR455,CHCHD4,PHC1,SOCS3,PAX6,EEF1E1,SLC25A5,NUP35,MRAS,NFYB,PIGA,CACNB4,B3GNT2,SYNGR1,SMARCA5,SRM,VEGFC,SRSF7,EPS8,MAT2A,KLF4,SNX10,ICAM1,MIR370,PDCD10,SHMT1,PADI2,TFRC,PTP4A3,CREB1 |
| 2.822e-03 | -5.87 | biogenic amine biosynthetic process | biological process | GO:0042401 | 36 | 19 | 18204 | 5365 |
AZIN2,TGFB2,SRM,ASMT,SAT2,SLC6A3,GPR37,NR4A2,MOXD1,AZIN1,OAZ1,HAND2,OAZ2,OAZ3,AANAT,DBH,ODC1,SAT1,PAOX |
| 2.822e-03 | -5.87 | demethylation | biological process | GO:0070988 | 36 | 19 | 18204 | 5365 |
APOBEC3H,APOBEC3G,CYP2C8,APOBEC3C,ALKBH4,APOBEC3F,KDM2A,KDM1A,APOBEC3B,CYP2C9,MMACHC,CYP2D6,APOBEC3D,CYP3A5,PPME1,PAX6,APOBEC3A,FBXL19,CYP3A43 |
| 2.822e-03 | -5.87 | USP24 (ubiquitin specific peptidase 24) | protein interactions | 23358 | 96 | 40 | 19454 | 5460 |
PHF21A,CCNF,LMBR1L,CHRM4,EGLN3,VIRMA,JUNB,CDC5L,COPS7B,CCAR2,RHOJ,YWHAG,COPS5,CSNK2A1,SUV39H1,HMGA1,CNOT2,WWP2,CUL3,GPR17,HNRNPD,FIS1,SMAD4,CPNE2,EP300,FAM168A,RPA3,CXCR4,SIRT7,KDM1A,NPTN,RP2,SOX2,HCST,TBK1,TP53,PGRMC1,CYB5B,PIH1D1,RPA2 |
| 2.822e-03 | -5.87 | ACAD10 (acyl-CoA dehydrogenase family member 10) | protein interactions | 80724 | 96 | 40 | 19454 | 5460 |
KLRC2,QRSL1,ACAA2,AQP3,OXSR1,TIMM10,TP53,HCST,NPY2R,KLRD1,SLC31A1,NPTN,TNFSF8,RASL10B,MRPS17,HS2ST1,SLC25A10,CXCR4,OSTM1,JAK1,EFNB1,HAPSTR1,SQSTM1,TAFAZZIN,NTRK3,KLK5,LAMP2,ETFBKMT,HNRNPC,P2RY10,ADCK1,CX3CL1,PRNP,MALSU1,APLNR,OPRL1,AIFM1,YBEY,TMEM108,FAHD1 |
| 2.822e-03 | -5.87 | RPRM (reprimo, TP53 dependent G2 arrest mediator homolog) | protein interactions | 56475 | 96 | 40 | 19454 | 5460 |
FCGR1A,PDZK1IP1,SLC38A1,FBXW11,TM4SF18,WDR20,TMEM106C,FATE1,OPRM1,CREB3,TMEM237,TSPO2,SNX3,MPP1,SPCS1,FNDC9,PLEKHF2,AMIGO1,CLDN9,SNX12,COQ8A,CERK,SCAND1,STOM,NRN1,SDCBP,LMNA,FBXL19,LPAR6,CDK4,SLC19A2,EHHADH,GNG13,GPR37L1,FGD2,ARFIP1,GAD2,BSCL2,SNX11,BMPR1A |
| 2.824e-03 | -5.87 | negative regulation of cell differentiation | biological process | GO:0045596 | 716 | 245 | 18204 | 5365 |
METTL14,SHOC2,PPARG,TLCD3B,PI16,SUFU,IRF1,MIR106A,MIR100,PIK3R1,TSPO,BTG2,NR2E1,UBASH3B,EZH2,LHX2,NF2,B2M,VEGFA,BMPR2,YTHDF2,MECP2,MIR181C,BMPR1A,FGF23,TGFB1I1,MIR137,NFE2L2,SLC6A4,FBXO7,SOX3,TLR4,DDIT3,CDK6,MIR140,THY1,FGL2,MIR590,PTPN11,TOMM70,CCL11,TMEM176B,PRDX2,IL18,CCDC85B,ITGAV,IL13,SOD2,MIR1-1,PDCD4,TNFAIP6,HOXB8,TP53,IFNG,BRINP1,ACTL6B,CTLA4,TRIB1,BCL7C,RNF10,F2,PTHLH,MIR222,LDB1,G6PD,MIR17,MIR214,RB1,FGF13,CITED1,SOSTDC1,NPPC,TENT5C,CXCL10,DUSP10,ADIPOR1,NOG,FCGR2B,HDAC6,GABPA,TRIM46,FBXW7,MIR98,LBX1,CDK5,RGS2,BCL6,HMG20A,MIR205,MIR495,HMGB1,BCL7B,GPR171,TRIM6,TRIM62,MSX1,MIR145,CCN3,NKX6-2,WEE2,RBPJ,MIR24-1,CERS2,SMAD3,ADIPOQ,TNF,LBH,TWSG1,ACTB,PSEN1,MIR146A,LILRB4,IFNA2,MIR30B,MIR21,PTN,CDC73,INHA,MSX2,SYT4,MIR149,IL4,ZBTB16,TCTA,RUNX1,RTN4,HDAC3,LDLRAD4,SOCS5,MIR208A,CAV3,MSTN,CBFB,WNT10B,RC3H2,MIR204,PAX6,IFNB1,TRIM11,CAV1,MAD2L2,VEGFC,GPR37L1,PPARA,GPR137,HEY2,MIR10A,SPRY1,MIR130B,LILRB1,LDLR,FOXP3,CCL3,FRZB,ACTL6A,YWHAH,MIR142,MIR107,MMP9,ASPM,IL6,ID4,MIR302B,FLCN,SFRP1,MYC,TP53INP1,EIF4E,MIR379,FERMT2,DLX1,TLR3,EPHA4,NKX3-2,RORB,FOXP1,IFRD1,CARTPT,MIR130A,MIR221,DICER1,IL2,CTDSP1,CCND1,SS18,CDK12,SNAI2,SOX9,ANP32B,TNR,CTNNA1,MIR320A,PAEP,XBP1,TWIST2,MIR448,RGMA,TMEM176A,HDAC5,GSK3A,TOB2,NRP1,NR1H2,MIR573,STAT1,PTEN,SMAD1,SDHAF2,GREM1,DRD3,SMAD4,HAND2,PROX1,PRMT5,SEMA5A,RFLNA,C1QC,SPP1,TMEM182,IL1B,DKK1,SOX2,CEACAM5,WNT7A,PPP3CA,EID2B,MIR9-1,MT3,SPRED2,NPR2,CTNNB1,FGF10,CALR,LRP3,MIR144,SKIC8,IL1A,MIR675,TGFB2,TCF23,SPRED1,BRD9,NFKBIA,KRAS,IGF1 |
| 2.828e-03 | -5.87 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 22 | 13 | 16828 | 4835 |
EZH2,SMARCB1,PTEN,IDH2,JAK2,TP53,RB1,KIT,CTNNB1,CBL,IDH1,HRAS,KRAS |
| 2.828e-03 | -5.87 | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma | 22 | 13 | 16828 | 4835 |
SMARCB1,PTEN,DICER1,CTNNB1,KIT,TP53,JAK2,ETV6,SS18,SF3B1,KRAS,HRAS,IDH1 |
| 2.852e-03 | -5.86 | ST7 (suppression of tumorigenicity 7) | protein interactions | 7982 | 359 | 125 | 19454 | 5460 |
SEC62,OTULINL,TOR1AIP2,GOSR2,PGRMC1,NOTCH2,FDFT1,VAPB,EMC9,ITGAV,AZGP1,CERS6,GDPD3,EMC1,VEZT,TMEM38B,SCFD1,ZMPSTE24,SPCS3,LMNB1,DCAF4,PRMT5,SEC61B,GPR89A,NFKBIA,ATP6AP2,B4GAT1,CHP1,REEP4,SNAPIN,SOX2,DNAJC25,FAF2,NETO2,MACO1,STBD1,EMC10,TAPT1,CRELD1,RPN1,STIM1,SEC11A,SCD5,RINT1,TMT1A,RETREG1,EMC8,NUP42,EMC6,DDRGK1,FAM241A,DDX50,PTDSS1,RHOG,CSTA,CDK5RAP3,S100A8,CYB5A,STX5,NUP35,HNRNPL,ATG16L1,RABL3,ARHGAP1,SEC22B,PDCL,LEMD3,JUP,LRRN1,SLC12A2,TMX4,USE1,SSR1,MTDH,SPCS2,TEX264,RAB29,LRRTM2,TMEM209,YKT6,GORASP2,HMOX2,C9orf72,CALHM5,RIC3,BICD2,LIG3,ATL1,VKORC1L1,SEC63,CTSB,DHRS13,UBIAD1,LBR,SPRR1B,PREB,CCDC47,BSCL2,STX18,EMC2,NSDHL,CNOT6L,FKBP8,SRPRB,LRP3,B4GALT7,TMEM199,EMC4,DHRS7,SELENOS,OSBPL8,POR,ESYT1,SMIM12,CDCA3,ITGA6,SRPRA,PTPN1,CAMLG,TMPO,LMAN1,DNAJC1,MARCHF4,ARL6IP5,PRNP |
| 2.878e-03 | -5.85 | Flnb (filamin, beta) | protein interactions | 286940 | 99 | 41 | 19454 | 5460 |
PPP1CC,CFL2,ARHGAP21,PPFIBP1,RAB5C,RALB,AP2A1,RHOB,RAP2C,RRAS2,AP2M1,RAP1B,DECR2,CTTN,TMEM237,RPL22,FCHO2,SPTAN1,YES1,PPP1R18,RALA,DAPK3,RAB14,CD59,ACTN4,RAP1A,SPTBN1,TMOD1,CAPZA2,JUP,SNAP23,CYBRD1,MYO1B,RAB1A,PALM2AKAP2,LIN7C,FLOT1,PACSIN3,CAPZA1,KRAS,G3BP1 |
| 2.878e-03 | -5.85 | TSC22D1 (TSC22 domain family member 1) | protein interactions | 8848 | 99 | 41 | 19454 | 5460 |
UBE2D1,CBL,CRMP1,TLE1,GSTK1,FAM20C,SYNJ2BP,BMPR1B,SPRED1,TAF5L,CTNNB1,GORASP2,NTAQ1,TSC22D3,HNRNPL,DDAH2,LRIF1,CCDC90B,ALB,RGS1,EED,MAP3K12,ACVR1,NCOA5,CARHSP1,TP53,CFTR,CD2AP,TGFBR2,SRPRB,ACVR1B,PTN,EMC1,PDHB,CA10,SFXN1,FAF1,RPA3,BMPR1A,NUP50,ERG28 |
| 2.885e-03 | -5.85 | EPHA4 (EPH receptor A4) | protein interactions | 2043 | 180 | 68 | 19454 | 5460 |
GAB1,SLA2,CIB2,CTNNA1,ANAPC2,SLC1A1,MB21D2,UMPS,TUBB,ARMC6,FERMT2,ESR2,NCKAP1,SRC,EFNA5,NIBAN2,PKP4,PTPN11,RPS29,GORASP2,HSP90AA1,EPHA2,RFC4,LIN7C,RHOU,BANF1,NUBP2,HADHA,CYFIP2,RNF5,FTSJ1,PIK3R2,POLDIP2,USP6NL,NOTCH2,BET1,NTPCR,JUP,FGFR1,SLC12A2,WDR6,EFNA3,HRAS,GJA1,SEC23A,FZR1,FCHO2,FAM118B,OS9,CAV1,PIK3R1,SHC1,DLG1,MYO1B,EPHA4,KRAS,CTNND1,POLDIP3,AHCYL1,SNAP29,CTNNA2,CTLA4,TUBB4B,TSPAN3,GNAZ,HGS,GNAI3,CASK |
| 2.885e-03 | -5.85 | GRK5 (G protein-coupled receptor kinase 5) | protein interactions | 2869 | 180 | 68 | 19454 | 5460 |
HSP90AA1,AP2A1,PPIG,YWHAZ,FTSJ3,CFL1,TUFM,MAT2A,COPS7A,TAB1,SPIN3,ARF1,EIF4A3,DLST,AVPR1B,JUP,SPTBN1,ATG16L1,PSMC1,SAP18,SKP1,STK38,ADRB2,RPL4,TACR1,SNCG,XRCC5,LYZ,YWHAB,MAP4,USP15,WDR12,DCAF5,PPFIBP1,YWHAG,HDAC6,TOR4A,CALR,MOV10,CAV1,DHX15,HSP90AB1,LYAR,SPTAN1,WDR82,COPS2,SIN3A,ALYREF,SRSF1,GYS1,MRTO4,TNFAIP8L1,GINS4,EEF1A1,EEF2,TOP3B,SNCB,OLA1,ARF4,COPS4,RCVRN,RUVBL1,RPL3,DHX9,AKT2,ABCF1,MAEA,TCOF1 |
| 2.886e-03 | -5.85 | nucleotide biosynthetic process | biological process | GO:0009165 | 252 | 95 | 18204 | 5365 |
UQCC3,SHMT1,ATP5MG,KARS1,PPT1,UCKL1,NPR2,ATP5F1B,ATP5PD,NUDT2,PRPS1,PPAT,NDUFA1,NDUFA5,PDHB,NME2,ATP5MK,NPPC,DCTD,ELOVL6,UCK1,GUCY1B1,ADCY2,ATP5F1D,ATP5MC1,NDUFB5,ACACA,ELOVL1,TYMS,DCK,PDHA1,NUDT12,ATP5PF,TECR,SDHB,UMPS,NDUFA2,ACAT1,DNAJC30,STOML2,ACSL4,ATP5PB,NMRK1,ELOVL3,ADK,NDUFS2,HACD2,GMPS,MMUT,IDO1,NDUFV2,NDUFB6,SLC25A1,NDUFAB1,NME1,NDUFB10,PNP,ATP5F1A,NDUFS8,MTHFD2L,DLAT,ACSS2,ATP5MC3,NDUFB7,NDUFA12,COX11,UCK2,UPRT,NDUFB4,ADCY3,ATP6V1A,ADSS2,AK2,ELOVL7,RRM1,HACD1,DCAKD,NME4,CMPK1,NDUFS3,ATP5F1E,AK3,SDHC,GUK1,NDUFC2,NDUFS6,PRPSAP1,AK5,LIPA,SLC52A3,ATP5PO,ELOVL4,NDUFB8,PAPSS2,DTYMK |
| 2.891e-03 | -5.85 | RNA modification | biological process | GO:0009451 | 172 | 68 | 18204 | 5365 |
SNRPD2,APOBEC3B,FTSJ3,THG1L,NHP2,MEPCE,URM1,TRMO,WDR6,BUD23,TFB1M,CTU1,SNRPE,METTL25B,DTWD2,SNRPD1,APOBEC3A,TSR3,KTI12,GTDC1,TMT1A,QTRT2,HNRNPAB,METTL2A,TRMT6,RAMAC,METTL14,APOBEC3H,TRUB1,SNRPG,RBM15B,TRMT61A,APOBEC3F,TRMT10B,ELP6,TRMT1L,DTWD1,HSD17B10,DKC1,HENMT1,CMTR1,TRMT13,SNRPD3,WTAP,VIRMA,APOBEC3G,FTSJ1,MRM2,TRMT112,TYW5,TRMT5,QNG1,GON7,DPH3,EMG1,APOBEC3D,APOBEC3C,OSGEP,SNRPB,TYW3,DUS4L,OSGEPL1,METTL6,THUMPD1,METTL15,CBLL1,ELP3,TRMT11 |
| 2.894e-03 | -5.84 | skin-scalp-malignant_melanoma-nodular | COSMIC cancer mutations | skin-scalp-malignant_melanoma-nodular | 13 | 9 | 16828 | 4835 |
KIT,HRAS,GNA11,CTNNB1,KRAS,IDH1,IDH2,GNAQ,PTEN |
| 2.894e-03 | -5.84 | stomach-carcinoma-mucinous_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-mucinous_adenocarcinoma | 13 | 9 | 16828 | 4835 |
KRAS,HRAS,TP53,MSH6,PIK3R1,STK11,PIK3CA,PTEN,NTRK3 |
| 2.894e-03 | -5.84 | skin-shoulder-malignant_melanoma-nodular | COSMIC cancer mutations | skin-shoulder-malignant_melanoma-nodular | 13 | 9 | 16828 | 4835 |
PTEN,GNAQ,IDH1,IDH2,KRAS,CTNNB1,KIT,HRAS,GNA11 |
| 2.894e-03 | -5.84 | central_nervous_system-brain-glioma-ependymoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_II | 13 | 9 | 16828 | 4835 |
TERT,PTEN,RB1,HRAS,KRAS,IDH2,IDH1,NF2,AKT1 |
| 2.894e-03 | -5.84 | anus | COSMIC cancer mutations | anus | 13 | 9 | 16828 | 4835 |
EWSR1,PIK3CA,GNAQ,TP53,KIT,HRAS,GNA11,KRAS,CTNNB1 |
| 2.894e-03 | -5.84 | mucinous_adenocarcinoma | COSMIC cancer mutations | mucinous_adenocarcinoma | 13 | 9 | 16828 | 4835 |
PTEN,NTRK3,STK11,PIK3CA,MSH6,PIK3R1,KRAS,HRAS,TP53 |
| 2.907e-03 | -5.84 | Gap-filling DNA repair synthesis and ligation in GG-NER | REACTOME pathways | R-HSA-5696397 | 25 | 15 | 10285 | 3229 |
RPA3,RFC2,POLD4,RFC5,POLE4,RFC3,POLE3,PCNA,LIG3,RPS27A,POLD2,UBA52,RFC4,RPA2,UBB |
| 2.910e-03 | -5.84 | ZNF16 (zinc finger protein 16) | protein interactions | 7564 | 35 | 18 | 19454 | 5460 |
RPL31,FAIM,PPAN,SRSF1,RPL3,PRKRA,HAPSTR1,NPM3,NOP53,PRNP,RPL19,ESR2,SURF6,RPL7A,RPSA,DDX39A,ZCCHC17,H1-1 |
| 2.910e-03 | -5.84 | PAK3 (p21 (RAC1) activated kinase 3) | protein interactions | 5063 | 35 | 18 | 19454 | 5460 |
ABCE1,COMMD2,RAMAC,MRPL52,RHOU,ARHGEF6,MRPS18C,HNRNPL,RHOJ,SNRNP27,CDC42,RAF1,TAX1BP3,ITGB8,GIT2,RASSF8,NCK1,MYO6 |
| 2.910e-03 | -5.84 | IL2RB (interleukin 2 receptor subunit beta) | protein interactions | 3560 | 35 | 18 | 19454 | 5460 |
HGS,IL2,IL15RA,SHC1,IL15,CISH,TUBA1A,SOCS3,IL2RG,PIK3R1,SYK,RAF1,JAK2,STAT5A,STAT1,MTDH,IL2RA,JAK1 |
| 2.910e-03 | -5.84 | Rprd1b (regulation of nuclear pre-mRNA domain containing 1B) | protein interactions | 70470 | 35 | 18 | 19454 | 5460 |
RPAP2,SUPT4H1,SUPT5H,POLR2D,CDC73,POLR2C,POLR2G,TOX4,SKIC8,ELOF1,JADE1,AKAP1,RPRD1A,STUB1,PPP1R10,POLR2B,POLR2I,DNAAF10 |
| 2.910e-03 | -5.84 | DBF4B (DBF4B-CDC7 kinase regulatory subunit) | protein interactions | 80174 | 35 | 18 | 19454 | 5460 |
SUV39H1,MDFI,LMO2,E2F4,MAP1S,BRCA1,HEXIM2,TRIM27,HAPSTR1,CDC7,ZNF655,PTEN,MAP1B,DDX39B,APEX1,SRPK2,KDM1A,SGF29 |
| 2.910e-03 | -5.84 | ZNF70 (zinc finger protein 70) | protein interactions | 7621 | 35 | 18 | 19454 | 5460 |
H1-5,ZNF668,E4F1,H1-1,SRP14,PRR3,RPL23A,ZFP64,NPM3,DGCR8,RPS10,RPL28,RPS13,SRSF4,RPL17,VIRMA,UTP23,RPL19 |
| 2.910e-03 | -5.84 | PRR5 (proline rich 5) | protein interactions | 55615 | 35 | 18 | 19454 | 5460 |
KRAS,HNRNPL,RHOJ,RHOH,DESI1,GPSM3,YWHAB,HGS,KCTD12,RHOG,LAMTOR1,BRCA1,RC3H2,YWHAZ,YWHAH,YWHAG,CUL3,SFN |
| 2.914e-03 | -5.84 | ATAD5 (ATPase family AAA domain containing 5) | protein interactions | 79915 | 76 | 33 | 19454 | 5460 |
RPA2,CBX3,MAP2K1,SOX2,TUBA1A,CA8,H2BC14,MDC1,RFC3,H3C1,STAU1,ASF1A,RABGGTB,MIS12,PCNA,RPS24,RPA3,RPL31,RFC4,S100B,BAX,BRD3,DCAF4,H2AC4,CSNK2A1,RFC5,DNAJC8,BAZ1B,ESR2,KLF9,APEX1,SNRNP40,ZNF330 |
| 2.914e-03 | -5.84 | ZNF106 (zinc finger protein 106) | protein interactions | 64397 | 76 | 33 | 19454 | 5460 |
STAMBPL1,YWHAB,MPHOSPH6,YWHAG,YWHAH,MYC,CREBBP,EGLN3,VIRMA,ESR2,MATR3,FBXO22,CSNK2B,LDLR,UBE2I,ZNF330,MIR21,MIR7-1,RPA2,CAPZA2,PPP1CB,SUPT5H,CCND1,E2F4,MDC1,TOLLIP,MIRLET7I,EMG1,EP300,RPS24,RPA3,RPL31,PML |
| 2.921e-03 | -5.84 | ferrous iron binding | molecular function | GO:0008198 | 26 | 15 | 18094 | 5411 |
TF,PHYH,ISCU,FTL,FTHL17,FTH1,ALKBH3,CDO1,EGLN2,FXN,ALKBH2,DNAJC24,DPH3,EGLN3,ACP5 |
| 2.921e-03 | -5.84 | steroid hydroxylase activity | molecular function | GO:0008395 | 26 | 15 | 18094 | 5411 |
CH25H,CYP2R1,CYP21A2,CYP27A1,CYP39A1,CYP2C8,CYP17A1,CYP7A1,CYP11B2,CYP1A1,CYP1B1,CYP2C9,CYP3A5,CYP3A43,CYP11B1 |
| 2.926e-03 | -5.83 | transcription factor TFIID complex | cellular component | GO:0005669 | 34 | 18 | 19108 | 5553 |
GTF2F1,TAF11,TAF7,TAF5L,TAF10,GTF2A2,TAF2,GTF2A1,GTF2H5,GTF2E2,ERCC3,GTF2H4,TCEA1,GTF2E1,GTF2B,TAF9,PAAF1,GTF2H2 |
| 2.927e-03 | -5.83 | Histone, subunit A | gene3d domains | 1.10.20.10 | 72 | 32 | 14470 | 4137 |
DR1,H2BC17,H2BW1,H2AZ2,H2AC1,H2AC25,TAF9,H2AC4,POLE3,H2BC14,H2AC6,TAF11,H2AB1,MACROH2A2,H2AC14,MACROH2A1,DRAP1,SUPT3H,H2BC12,H2AJ,H2BC1,H2AX,NFYB,SUPT7L,H2BC9,CHRAC1,H2AC7,H2AZ1,POLE4,CENPW,SOS2,H2BC11 |
| 2.928e-03 | -5.83 | TNFRSF10C (TNF receptor superfamily member 10c) | protein interactions | 8794 | 102 | 42 | 19454 | 5460 |
ENDOD1,TMEM184C,ATP1A3,FAS,SLC20A1,PDZK1IP1,ORC5,LHFPL6,SLC41A1,SLC6A6,NR2F6,CD81,DNAJC1,SRPK2,TMEM45B,SLC38A2,CYB5R3,CXCL14,VAMP3,SGTA,LRRC4B,ZHX1,STOM,LMNA,TMEM94,STX12,TTI2,MTCH2,TP53,AGTRAP,RAP1A,TCAF2,ASZ1,SLC29A1,GPR37L1,LPAR1,MYORG,TNFSF10,SLC6A8,SLC35F2,LPAR2,MRPS18B |
| 2.928e-03 | -5.83 | TMX3 (thioredoxin related transmembrane protein 3) | protein interactions | 54495 | 102 | 42 | 19454 | 5460 |
AP1G2,SEC61B,HSD17B11,DUSP6,LMBR1L,ST8SIA5,CCNF,NUP35,EGLN3,PRNP,HNRNPL,MTM1,VAMP5,CUL3,CSK,DPP4,ST3GAL4,CHCHD4,DRG2,DERL1,FHL3,TMEM106B,TMT1A,EHD4,DUSP9,RPA3,HS2ST1,IMMP2L,PDE2A,RER1,HSCB,DUSP22,CLEC2B,SEC62,DNAJC25,OTULINL,FUT8,CCDC47,B3GALT4,CYB5B,PRKAG1,LMNA |
| 2.934e-03 | -5.83 | Cyclin D associated events in G1 | REACTOME pathways | R-HSA-69231 | 39 | 21 | 10285 | 3229 |
MNAT1,CDKN2D,CDKN1B,CCND3,CDK4,CDKN1A,SKP1,CDK7,CCND1,UBA52,RPS27A,UBB,TFDP2,PPP2R1A,E2F4,CKS1B,CDK6,PPP2CB,RB1,CDKN2C,CCNH |
| 2.934e-03 | -5.83 | G1 Phase | REACTOME pathways | R-HSA-69236 | 39 | 21 | 10285 | 3229 |
PPP2CB,RB1,CCNH,CDKN2C,RPS27A,UBA52,CKS1B,CDK6,E2F4,PPP2R1A,TFDP2,UBB,CCND1,SKP1,CDKN1A,CDK7,MNAT1,CDK4,CCND3,CDKN1B,CDKN2D |
| 2.941e-03 | -5.83 | APPL1 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) | protein interactions | 26060 | 174 | 66 | 19454 | 5460 |
MYO6,YWHAZ,RHOB,LAMTOR1,NRP1,EPHA2,NTRK3,RSPH1,AKT1,AR,ARL6IP6,RBBP4,DLG4,FGFR1,RPRD1B,ADIPOR1,BET1,GABARAPL2,PIK3R2,LPAR1,HDAC3,GABARAP,ARPC2,RAB5A,HDAC5,TRAF6,ARL14EP,YWHAB,HSPB1,ID1,CBL,ADIPOR2,INO80E,PIK3R1,ATG9A,KXD1,YWHAG,YWHAH,PRNP,OCRL,PLEKHF2,FHIP1B,STX6,LMAN1,FBXO32,DNM2,NRSN1,MAP1LC3A,ACTR2,PIK3CA,MTA2,PNMA5,TP53,MAP1LC3B,TRAF2,GABARAPL1,TTC4,KRAS,RBBP7,AKT2,CIPC,CTTNBP2,IGF1R,RTCB,NTRK2,RUVBL2 |
| 2.942e-03 | -5.83 | Syntaxin/epimorphin_CS | interpro domains | IPR006012 | 15 | 10 | 18521 | 5414 |
STX1A,STX6,STX17,STX10,STX12,STX7,STX11,STX18,STX5,STX16 |
| 2.942e-03 | -5.83 | Histone_H2A_CS | interpro domains | IPR032458 | 15 | 10 | 18521 | 5414 |
H2AC14,H2AC1,H2AX,H2AC4,H2AZ2,H2AC7,H2AZ1,H2AC25,H2AC6,H2AJ |
| 2.961e-03 | -5.82 | regulation of amide metabolic process | biological process | GO:0034248 | 81 | 36 | 18204 | 5365 |
NTRK2,PRNP,SP1,MIR153-1,MIR361,IFNGR1,PICALM,RTN4,MIR186,ORMDL3,CLU,ORMDL1,MIR206,MIR16-1,GSK3A,MIR195,ROCK1,CSNK1E,CHRNA7,LRRTM3,MIR29A,SPON1,TNF,NFE2L2,MIR29C,SLC7A11,IGF1,TP53,ROCK2,IFNG,MIR24-1,SPHK2,MIR455,EPHA4,MIR298,MIR339 |
| 2.961e-03 | -5.82 | Ras protein signal transduction | biological process | GO:0007265 | 81 | 36 | 18204 | 5365 |
RALB,RAPGEF5,GNB1,RGL1,ERAS,CRKL,SHOC2,RFXANK,HRAS,RASGRP3,CCNA2,GRAP2,RGL2,RASGEF1C,RIT2,DOK6,USP8,CDKN1A,DOK5,RRAS2,TP53,MAPKAPK5,SOS2,BRAP,G3BP2,GRAP,G3BP1,DOK4,RASGRP2,SDCBP,IGF1,KRAS,RALA,RB1,MRAS,RIT1 |
| 2.962e-03 | -5.82 | CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 9646 | 211 | 78 | 19454 | 5460 |
SUPT5H,MAP1LC3B,SOX2,CDK8,POLR2G,POLR2C,POLR2D,NUPR1,RPS23,NEK9,EMC2,H3C1,KRAS,PSMA5,SSRP1,RIGI,PTGES3,HMGA1,TCEANC2,CSNK2A1,XPO1,ELOC,SKIC8,DDX23,SMAD9,YWHAB,RPL12,EEF1AKMT3,FZR1,TOP1,SUMO2,CDK9,CETN2,G6PD,AKR7A2,MYLIP,ACSS2,FAM161A,ING5,POLR1D,CDK7,LMNA,RPA2,TOX4,PRSS23,ACACA,RPA3,SNRPA,RPL27,RCCD1,ELOF1,EP300,YAF2,TCEA1,DGCR8,COIL,TRIM52,SUGP1,MYC,PTPN11,CIAO1,PRPF31,ANO3,DNAJC8,AR,SNRPB,CDC73,RIT1,DNAJB6,UBE2H,H1-1,ZNF330,CSNK2B,SYT2,POLR2F,POLR2B,PPP1R10,ESR2 |
| 2.963e-03 | -5.82 | central_nervous_system-choroid_plexus-other-choroid_plexus_carcinoma | COSMIC cancer mutations | central_nervous_system-choroid_plexus-other-choroid_plexus_carcinoma | 7 | 6 | 16828 | 4835 |
IDH2,SMARCB1,IDH1,TP53,TERT,KIT |
| 2.963e-03 | -5.82 | autonomic_ganglia-ganglioneuroblastoma | COSMIC cancer mutations | autonomic_ganglia-ganglioneuroblastoma | 7 | 6 | 16828 | 4835 |
IDH1,IDH2,CTNNB1,KIT,TP53,TERT |
| 2.963e-03 | -5.82 | subependymoma_Grade_I | COSMIC cancer mutations | subependymoma_Grade_I | 7 | 6 | 16828 | 4835 |
PTEN,NF2,IDH1,IDH2,TERT,TP53 |
| 2.963e-03 | -5.82 | choroid_plexus_carcinoma | COSMIC cancer mutations | choroid_plexus_carcinoma | 7 | 6 | 16828 | 4835 |
TERT,SMARCB1,KIT,TP53,IDH1,IDH2 |
| 2.963e-03 | -5.82 | central_nervous_system-brain-glioma-subependymoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-subependymoma_Grade_I | 7 | 6 | 16828 | 4835 |
TERT,PTEN,TP53,IDH2,NF2,IDH1 |
| 2.963e-03 | -5.82 | skin-shoulder-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-shoulder-other-seborrhoeic_keratosis | 7 | 6 | 16828 | 4835 |
PTPN11,AKT1,HRAS,PTEN,TERT,PIK3CA |
| 2.963e-03 | -5.82 | skin-neck-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-neck-other-seborrhoeic_keratosis | 7 | 6 | 16828 | 4835 |
PTPN11,PTEN,AKT1,TERT,PIK3CA,HRAS |
| 2.963e-03 | -5.82 | skin-chest-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-chest-other-seborrhoeic_keratosis | 7 | 6 | 16828 | 4835 |
HRAS,PIK3CA,TERT,PTEN,AKT1,PTPN11 |
| 2.972e-03 | -5.82 | FOXA3 (forkhead box A3) | protein interactions | 3171 | 51 | 24 | 19454 | 5460 |
STAT1,ARMC6,ACSL4,FUBP3,ZBTB33,FOXP3,RMDN3,RB1,ALB,ST3GAL2,TLE1,TOMM40,MCM4,NUP107,HMGB1,HELLS,RPA3,RPA2,STOM,FEN1,TP53,MAP2K3,DDX39A,PPARA |
| 2.972e-03 | -5.82 | OTUD5 (OTU deubiquitinase 5) | protein interactions | 55593 | 51 | 24 | 19454 | 5460 |
NEDD8,SSRP1,GPX4,BAG2,ARPC3,RNF146,POLR2C,TP53,CCAR2,TRIM35,PDCD5,MAD2L2,EGLN3,CACYBP,POLR2B,GYS1,LDLR,PTEN,IGBP1,LANCL2,SUB1,TNFAIP3,MOV10,NONO |
| 2.972e-03 | -5.82 | MAPK11 (mitogen-activated protein kinase 11) | protein interactions | 5600 | 51 | 24 | 19454 | 5460 |
TAB1,ELK1,DUSP10,ESR2,GYS1,SH2D1A,RPS6KA4,HTRA2,PTPN5,PPM1D,BAG3,HDAC3,PPM1G,DUSP9,PML,MAPKAPK3,ZNHIT1,MAPKAPK5,CCND1,YTHDF2,SOCS3,JUN,ARHGAP12,ELK4 |
| 2.972e-03 | -5.82 | Samm50 (SAMM50 sorting and assembly machinery component) | protein interactions | 68653 | 51 | 24 | 19454 | 5460 |
DGCR8,AKAP12,MRPS17,SPECC1L,CCT8,MYO1B,CAPZA2,TAF2,KLHL12,DCAKD,ATP5PB,CCT5,PRDX3,PRDX2,MED17,TCP1,SPTAN1,CHCHD3,CCT7,KLHL7,CCT2,XPOT,C9orf72,CCNQ |
| 2.975e-03 | -5.82 | negative regulation of organelle organization | biological process | GO:0010639 | 340 | 124 | 18204 | 5365 |
PARL,WDR44,SLC25A5,IK,HNRNPC,FGF13,TESK1,TMEM39A,TMSB4X,TMOD2,BCL2L1,PSMD10,PHF23,MAD2L1,CYRIB,SLC35F6,FEZ1,PPIF,PSMG2,BECN1,PICK1,PAK2,CCNF,BAZ1B,FKBP4,CTNNA2,MIR214,MET,BUB3,MIR20A,SUB1,MID1IP1,GPX1,TFRC,ADD1,SLC25A4,TRIM32,TMOD3,SEC22B,BAK1,MAP1B,SPC24,CAPZA1,STN1,MUL1,BOK,SPTBN1,IGF1,TOM1L2,SMAD4,SLC25A31,HDAC6,TBC1D4,NUF2,AKT1,ARFGEF1,DYRK1A,LMNA,GCLC,CLU,TRIM37,CAPZA2,CAV3,ADCK1,SWAP70,CAPG,TNKS,SSH3,PRELID1,NDC80,MKKS,RAD21,MAD2L2,MIR21,MTM1,TNKS2,NBN,FXN,MIR149,STMN2,PPARG,SCFD1,MAPRE1,TRIM54,BRCA1,KLHL22,TSPO,PIK3R1,TMOD1,F11R,DCP2,CDC20,ACAA2,NUPR1,USP30,TOM1L1,FLCN,TMSB10,IER3,BMERB1,SPTAN1,HNRNPA1,TP53,CAMSAP2,ADD2,SPEF1,ZNF207,LPAR1,PIK3CA,SLX1A,GHITM,GDI2,EPS8,MAP4,RNF41,TMEM14A,CEP97,CLIP3,HUWE1,SRC,AURKAIP1,INPP5K,SMARCA5,RAD1 |
| 2.993e-03 | -5.81 | RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1) | protein interactions | 10616 | 168 | 64 | 19454 | 5460 |
NDUFAF3,LPXN,PRKCA,RAB9A,PCGF2,PRKCB,PML,UBE2D3,UBE2K,TTC23,CUL3,TNFAIP3,CREBBP,LMO2,SLC25A1,XPOT,HSP90AA1,PTEN,PSMA6,UBE2S,TNFRSF1B,FKBPL,ATP6AP2,TRAF1,OTUD6A,SMURF1,IREB2,NR1I2,UBE2L3,UBE2V2,PSMD4,TRAF2,CARTPT,TP53,HGS,OTULIN,RNF181,TAB2,TLR3,MINDY3,MOXD1,TRIM21,LDLRAD4,LTBR,RIGI,ENKD1,BACH1,RBCK1,PSMA1,TNF,RNF115,SPATA2,TENM3,ZFAND2B,USP2,MAGOH,USP15,TRAF6,BCL10,UBE2D1,CETN3,EEF1AKMT3,UBE2N,DBT |
| 2.993e-03 | -5.81 | POU2F1 (POU class 2 homeobox 1) | protein interactions | 5451 | 168 | 64 | 19454 | 5460 |
PGR,ECHDC1,PPIA,KRT8,H2AC4,HMGA1,NFKB1,IRF9,FOXC2,GAPDH,NT5C2,TNF,KCTD17,HNRNPK,FBXO25,RPS4X,MNAT1,PAX6,RPL31,SCYL2,SNIP1,TRIM21,BAG2,RPS24,HSD17B10,ARPC3,VDR,SP4,TXNRD1,EEF1A1,SOX2,ATP5F1B,STAT5A,CEBPE,EAF2,VIRMA,CREB1,ZNF330,ELK3,TUBA1B,RPL37A,PRMT5,UBE2I,EPCAM,BRCA1,PKNOX1,LMNB1,HSP90AA1,SP1,HOXC4,CSK,NFYA,AR,SNX24,MSX1,HSPA5,BANF1,XRCC5,HSPA8,ZMYM6,FOXS1,RPS14,SPTBN1,PRR13 |
| 3.005e-03 | -5.81 | TUBB4A (tubulin beta 4A class IVa) | protein interactions | 10382 | 208 | 77 | 19454 | 5460 |
TSHR,CDC42,GABRA1,ALKBH3,HEXIM1,TCP11L1,FGFR1,CST11,HSPA8,TNFAIP1,EP300,BAP1,DNAJC3,SIRT7,METTL22,HSPA5,NF2,FBXW7,STAU1,FBXO7,RSPH1,ETFBKMT,CUL3,SP1,STK11,ANAPC4,ICAM1,KLK5,ILK,FAS,CCT2,PRSS8,CCNF,TUBA1B,KCTD9,TUBB,MGARP,B3GNT2,UBL4A,RAF1,SELENOF,OTULIN,TUBB4B,TFCP2,BMPR2,CHMP4C,NGB,EMC2,OSTM1,FBXO25,MEPCE,SAR1B,EPHA4,TNF,XPO1,YWHAG,CD81,HDAC6,PPM1D,DDRGK1,FAM174A,POU5F1,HAX1,SLC2A1,AGR2,TES,CLN8,AIFM1,EEF1AKMT3,PHB1,EGLN3,ELK1,CCT7,FZR1,DYNC1I2,TCP1,SUMO2 |
| 3.005e-03 | -5.81 | PI4KA (phosphatidylinositol 4-kinase alpha) | protein interactions | 5297 | 208 | 77 | 19454 | 5460 |
STAU1,NPTN,STX7,CDSN,RHOU,RAB9A,AKAP1,SDC2,JUP,CRYAB,PITPNA,PGRMC1,DUSP14,NPY2R,CDC42,RND2,RHOJ,ESR2,MAD2L2,VIRMA,APLNR,CD79B,S1PR4,LMBR1L,HYCC1,LORICRIN,CCNF,CRYBB3,ANAPC2,CD226,RHOB,LAMTOR1,RIT1,KLK5,OPRM1,RAB11A,CUL3,MYC,RAB2A,HYCC2,DNAJC5,KRAS,PTGES3,FLOT1,CD83,TCOF1,NDUFA4,IGF1R,TESK2,CA14,NUPR1,SMARCB1,RND3,CHRM3,TOP3B,SOX2,RHOH,ARF6,SPPL3,EGLN3,ILVBL,EEF1AKMT3,RAB35,HRAS,SYNCRIP,CD274,RAC2,CD4,GJA1,RHOG,MED4,DNAJC7,HAX1,FAM174A,YWHAG,P2RY10,YWHAH |
| 3.006e-03 | -5.81 | Toll-Like Receptor Pathway 2 | SMPDB pathways | SMP0069593 | 31 | 20 | 1369 | 531 |
TLR8,TLR9,IKBKB,MYD88,TLR1,TIRAP,TLR5,CD14,NFKB1,TAB1,LY96,TLR4,NFKBIA,TLR2,TLR7,TOLLIP,TLR6,TLR3,TAB2,TRAF6 |
| 3.009e-03 | -5.81 | Interleukin receptor SHC signaling | REACTOME pathways | R-HSA-912526 | 255 | 101 | 10285 | 3229 |
KRAS,MAP2K1,RAP1B,RAF1,WDR83,FGF22,UBA52,DUSP9,SRC,FRS3,PSMD10,FGF10,PSMA5,FGF23,PAQR3,MET,PEBP1,PSMB3,PPP2R5E,SPTAN1,PIK3R2,IL2RG,FGF1,PPP2R5A,DUSP6,YWHAB,PSMA1,PSMC3,PHB1,PSMD4,SPRED1,RPS27A,IL3,PSMB4,SHC1,RASGRP3,DUSP1,SEM1,IL5,LAMTOR2,KIT,PPP2CB,HRAS,PIK3CA,PSMA6,PEA15,PSMB2,PSMD1,LAMTOR3,CAMK2G,IL2RB,FGF16,PSMC1,CUL3,VWF,PSMD14,PPP2R1A,UBB,PSME1,ANGPT1,PPP5C,SPTBN1,FGF17,PSMD7,PSMB10,PSMB11,PSMC5,FGFR1,IL2,PSMA4,CSK,BRAP,DLG4,PSMA2,PSMB6,PSMB1,PIK3R1,JAK2,PSMB7,INPPL1,PSMD3,PSMC4,PSMB5,PSMA3,MAP3K11,DUSP10,NEFL,HBEGF,PSMD6,PSME2,FGF3,IL2RA,SPRED2,PSMB9,RAP1A,SHC3,CSF2,PIK3R3,PSMD12,JAK1,FGF7 |
| 3.010e-03 | -5.81 | dentate gyrus development | biological process | GO:0021542 | 24 | 14 | 18204 | 5365 |
EMX2,TUBA1A,CDK6,ATAT1,LARGE1,FXR2,PROX1,NEUROD6,TMEM108,PTEN,DRD1,POMT2,NR2E1,BTG2 |
| 3.011e-03 | -5.81 | UFM1 (ubiquitin fold modifier 1) | protein interactions | 51569 | 108 | 44 | 19454 | 5460 |
CRIP1,DDRGK1,CDK5RAP3,UBE2D1,PSMB1,MTAP,MIF,RPS16,G6PD,ESD,TP53,ARPC3,ACTR2,RAD23B,TAGLN3,HSPE1,VDAC1,KRAS,SAR1B,AHCYL1,CAPG,CFL1,HMGCS1,SAYSD1,UBE2E3,RC3H2,UBE2H,OSGEP,PSPC1,S100A6,RPL19,UBE2V2,UBE2L3,TPT1,SPR,UBE2W,UBA52,MRPL12,CNPY3,SOD1,TTC1,UBE2D3,UFL1,CSRP1 |
| 3.017e-03 | -5.80 | ST13 (ST13 Hsp70 interacting protein) | protein interactions | 6767 | 165 | 63 | 19454 | 5460 |
F2,SFN,SUB1,CUL2,BAG3,DNAJC5,CFL2,PIP4K2C,LAMTOR1,HSP90AA1,SMAD2,TSSK1B,CCNF,ALB,SGTA,TSN,DAPK1,CLIC4,RBFOX2,DET1,PPP1CB,CDC42,EMC9,GRIK1,JUP,RPA2,VAV2,HEXIM1,KLC2,RPA3,CXCR4,BAP1,AKAP1,PPIH,HSPA8,TTR,PACSIN3,PSMD3,YWHAG,PTGER4,YWHAB,DNAJC7,DCAF11,DSTN,NELL2,OLFM2,CPNE1,FZR1,RPS10,LMAN1,MTCH2,RAF1,ACTN4,MOB3C,FAF1,SRSF8,DNAJB4,RPAP3,WASL,ASF1A,KRAS,RIGI,PSEN1 |
| 3.017e-03 | -5.80 | FLT1 (fms related receptor tyrosine kinase 1) | protein interactions | 2321 | 165 | 63 | 19454 | 5460 |
TNPO3,SEC63,FBXO22,YES1,MACROH2A1,SEC61A1,EIF2S2,VEGFA,SERPINH1,NSA2,IGF2BP1,XPOT,NRP1,PTPN11,SMARCA5,PYGB,MRPL41,NUBP2,BANF1,RARS1,CDK1,MRPS34,CCL3,RAB6A,ETF1,CNP,PSMB3,PAFAH1B1,LANCL1,SURF6,ILVBL,EIF2S1,ARF6,XPO5,MRTO4,UBE2N,KRR1,COQ8A,SRPRA,DNM2,OSBPL8,MAGOH,CBL,NCK1,SHC1,SLC2A1,CTNNB1,GLO1,KARS1,BAZ1B,PIK3R1,RAD21,ARF4,TMEM33,SRPRB,FHL3,MYO1B,NDUFA4,PPAN,CRKL,GFPT1,TRMT1L,STRBP |
| 3.027e-03 | -5.80 | GPR21 (G protein-coupled receptor 21) | protein interactions | 2844 | 79 | 34 | 19454 | 5460 |
GPR89A,FZD3,GJA1,RETREG3,PTPN1,OTUD6A,TLCD4,UBB,ATP5F1B,KCNJ8,SLC6A6,ATP5F1A,ATP5MG,VEZT,BTN2A2,TMEM179B,FITM2,ZMPSTE24,TMEM164,MIA2,TCEA1,CXCR4,HSDL1,CERS6,LPAR1,RHBDD3,ST7,LGR4,SLC29A1,SLC19A2,ATP5PB,TMEM184B,TSPAN3,PTRH2 |
| 3.027e-03 | -5.80 | CDKN2D (cyclin dependent kinase inhibitor 2D) | protein interactions | 1032 | 79 | 34 | 19454 | 5460 |
GORASP2,NDUFB7,H1-1,ZNF688,LSM3,BRCA1,NIF3L1,NR4A2,AK2,CDK6,TSG101,CEP19,NMI,CGGBP1,CFAP90,THAP1,CDK4,RBM12,DDIT4L,TBC1D17,BTG1,SH3GLB2,SH3GLB1,RARRES2,SDCBP,CTBP1,FHL3,PICK1,CDKN2C,UQCC2,CCND3,RIGI,PSMA1,NME4 |
| 3.027e-03 | -5.80 | ZBTB14 (zinc finger and BTB domain containing 14) | protein interactions | 7541 | 79 | 34 | 19454 | 5460 |
MFAP1,RAD1,ATP5PO,RPA2,SDCBP,KLF3,MAD2L1BP,H2AX,DDX39A,KLF12,RPS7,FAM161A,MRPL11,TP53,AP1M1,ENKD1,ZBTB14,EIF1AD,EPHA2,BRCA1,GORASP2,ZCCHC10,CUL3,NAA11,APEX1,SNRPB2,KLF9,CEP19,ZMAT2,SYNCRIP,RPL9,POLR2L,ELK3,SCNM1 |
| 3.027e-03 | -5.80 | RAMAC (RNA guanine-7 methyltransferase activating subunit) | protein interactions | 83640 | 79 | 34 | 19454 | 5460 |
EIF1AX,GNG10,KRTAP8-1,E2F4,PLSCR4,RAF1,MAPK1IP1L,HNRNPK,RP2,RAMAC,PSMA3,RINT1,FAM168B,HCFC2,PLSCR1,TSNAX,AKAP8L,HSP90AA1,PEA15,KPNA1,TRIM23,NIF3L1,KPNA6,COPS5,CUL3,CUL2,MYC,RBM42,CAND1,SF3B4,TRIM27,PRR3,PHB1,THOC2 |
| 3.027e-03 | -5.80 | PRDM15 (PR/SET domain 15) | protein interactions | 63977 | 79 | 34 | 19454 | 5460 |
H1-1,RPL7A,RPL26,PRNP,RPL13A,LYAR,RPS16,RPS10,HNRNPL,RPL19,ESR2,SURF6,ZNF330,RPL8,RPS3,SRP14,RPS9,RPL37A,FGFBP1,PRKRA,LLPH,RPLP0,RPSA,H1-5,H1-3,RPL4,NPM3,DGCR8,RPL28,SRSF4,RPL31,RPL3,CPNE2,RPL23A |
| 3.034e-03 | -5.80 | SMC4 (structural maintenance of chromosomes 4) | protein interactions | 10051 | 258 | 93 | 19454 | 5460 |
LGR4,PPP2R1A,MOB3C,SMARCB1,IFT22,MTA2,HDAC11,EZH2,RUVBL2,AHCYL1,RAD21,MCM6,RUVBL1,G3BP1,KRAS,RBBP7,DDRGK1,ATG7,UBXN6,POU5F1,DDX23,FBXO32,SIN3A,EGLN3,SPTAN1,SUMO2,CCAR2,NEK7,RFXANK,PIH1D1,EP300,HSPA8,PSMC1,STAU1,MCM4,PSMD1,CUL3,MYC,RIT1,COP1,PRMT5,DPEP1,NFKBIA,LMBR1L,ESR2,TRIM29,RBBP4,FBXO22,MATR3,ACTR1A,KBTBD4,COMTD1,PSMC3,TBC1D4,ABCE1,MAP1B,MEPCE,VTA1,KPNA2,USP15,TOPBP1,EEF1AKMT3,CD274,CDC5L,CDK9,MYL12A,FZR1,CFTR,FAXC,GABRA1,ATG16L1,ACACA,HECTD1,HEXIM1,METTL14,DCTN4,RPA2,SQSTM1,SIRT7,DVL2,BAP1,RPA3,DEPDC1B,SMARCA5,SLC25A1,UBE2H,PTEN,SRP54,PSMC5,GANAB,CCNF,VIRMA,ADRM1 |
| 3.034e-03 | -5.80 | UBAP2L (ubiquitin associated protein 2 like) | protein interactions | 9898 | 258 | 93 | 19454 | 5460 |
G3BP1,KRAS,IMMP2L,HNRNPDL,PABPC1,LSM14A,EWSR1,ZC3H7A,RTCB,SKA3,VAMP2,EZH2,MOB3C,GTPBP1,B3GNT2,RAF1,TOP3B,ISG15,HNRNPL,FAM98A,SUMO2,EGLN3,PEG10,FUBP3,PHB1,MED4,DDX1,CNOT2,WWP2,XPO1,CPEB1,FXR2,YTHDF1,STAU1,SKP1,G3BP2,MCRIP2,SF3B1,PPT1,LARP4B,NUFIP2,PIH1D1,PRRC2A,FBXW11,BRCA1,HTRA2,LSM14B,ILK,RIT1,MYC,CUL3,BTF3,BAG3,CNOT6L,RIGI,GARRE1,DISC1,FBP1,YTHDF2,TNRC6C,FZR1,EIF4E2,COPS5,FBXW7,RPL4,BAP1,SIRT7,PML,LSM12,SMG5,SQSTM1,RNF113A,HEXIM1,TPT1,AGO1,RBMS2,NDN,SCML2,MYG1,VIRMA,CCNF,OPTN,SMAP2,RTRAF,ACAT1,PTEN,RPS20,SPOP,RC3H2,UBE2H,ETFBKMT,CEP85,AR |
| 3.040e-03 | -5.80 | LAS1L (LAS1 like ribosome biogenesis factor) | protein interactions | 81887 | 162 | 62 | 19454 | 5460 |
MYC,OST4,CUL3,PSKH1,LMNB1,UBE2H,CCNF,PSPC1,PELP1,ZNF330,EIF2AK2,TUBB,SNRNP40,RPGRIP1L,RPL10,MAD2L2,SRPK2,APEX1,SLC16A10,H2AB1,CDK7,RPA2,GRM2,RPA3,PML,SIRT7,MTDH,RNF113A,UFL1,NPM3,STAU1,COIL,IFI16,XPO1,DNTTIP1,DDRGK1,DDX23,HAX1,DNAJC7,DRG1,RCHY1,FBXO32,MAGED2,CAND1,RPS16,SUMO2,RBM42,EGLN3,CDC5L,ZBTB2,RAF1,KBTBD4,SOX2,AURKAIP1,CDK8,RPN1,SRP72,SNIP1,RPL31,RPS24,MDC1,IMMP2L |
| 3.047e-03 | -5.79 | TNFRSF1A (TNF receptor superfamily member 1A) | protein interactions | 7132 | 205 | 76 | 19454 | 5460 |
ARRDC3,HSPA8,BIRC2,PRKCB,TANK,SUMO1,SYK,PRDX3,CLIP3,CSNK1A1L,ZNF770,UTP15,STAMBP,TNFRSF1B,OPTN,MSN,UBE2I,SGTA,PHAX,MOB4,DAPK1,STAT1,TRAF1,JAK2,SRC,TNPO3,UBB,PTPN11,AKT1,FGFR1OP2,TNFAIP3,AR,OTUD7B,PIP4K2C,FAS,MAGEH1,HTRA2,HSP90AA1,STK11,SIKE1,HNRNPA2B1,LTA,JAK1,FBXO11,RBCK1,TNF,FASLG,TBK1,CSNK1E,TRAF2,NFKBIL1,PIK3CA,RNF8,TAB2,SYNCRIP,CDK6,MFSD5,MCL1,LTB,CAV1,SLMAP,PRELID1,USP2,DHRS7,PIK3R1,UTP6,CRADD,SPATA2,TRAF6,IKBKB,TRPC1,BCL10,DOLK,TNFSF13,HNRNPD,CBL |
| 3.049e-03 | -5.79 | RNPC3 (RNA binding region (RNP1, RRM) containing 3) | protein interactions | 55599 | 43 | 21 | 19454 | 5460 |
ZMAT5,SF3B1,SNRPD2,CPSF1,SF3B6,SNRPB2,SNRPG,SRPK2,ESR2,SNRNP40,SNRPD3,FBXW7,PRNP,KRAS,SNRPB,DDX39A,SNRPN,SNRPE,SMAD2,SNRNP70,ZCRB1 |
| 3.049e-03 | -5.79 | GMPPA (GDP-mannose pyrophosphorylase A) | protein interactions | 29926 | 43 | 21 | 19454 | 5460 |
TUBB,EIF2B5,DCUN1D1,LSM8,EGLN3,TMPO,FBXO32,PML,PHB1,ZYX,CCNF,HSPA8,NCK1,PAK5,ZNF688,CDR2,GMPPB,CUL3,GMPPA,AKT1,CFTR |
| 3.049e-03 | -5.79 | PEDS1-UBE2V1 (PEDS1-UBE2V1 readthrough) | protein interactions | 387522 | 43 | 21 | 19454 | 5460 |
RNF40,GMPPB,RAF1,STOM,TRAF6,TMEM31,CHORDC1,NCR3LG1,NME2,HSD17B10,HINT1,UBE2N,TMX2,STUB1,SOD1,APEX1,DCUN1D1,UBE2K,YKT6,TAGLN2,CAND1 |
| 3.049e-03 | -5.79 | IRF2BPL (interferon regulatory factor 2 binding protein like) | protein interactions | 64207 | 43 | 21 | 19454 | 5460 |
AR,CTNNB1,ETFB,CUL3,TBK1,IRF2BPL,FOSL2,DCK,CFAP298,BAG2,KLF10,HSPA8,TSG101,VGLL4,IRF2,VIRMA,ESR2,KCTD17,PRNP,IRF2BP1,NPM3 |
| 3.049e-03 | -5.79 | TSSK1B (testis specific serine kinase 1B) | protein interactions | 83942 | 43 | 21 | 19454 | 5460 |
CACYBP,ATP5PD,PTGES3,HSP90AB1,KRAS,SNX24,PRKCE,TGFBR2,GPHN,HSPA8,AIP,STUB1,FAM229B,HSP90AA1,AK2,FKBP4,MCM3,ST13,TIMM8A,TUFM,CTNNB1 |
| 3.056e-03 | -5.79 | Nono (non-POU-domain-containing, octamer binding protein) | protein interactions | 53610 | 25 | 14 | 19454 | 5460 |
LYAR,CPNE1,RPL23A,GSK3A,CTTN,RBM5,SNRPA,TFIP11,NOL7,YWHAZ,LARP4B,CTBP1,DIS3L,CD2BP2 |
| 3.056e-03 | -5.79 | TTLL1 (TTL family tubulin polyglutamylase complex subunit L1) | protein interactions | 25809 | 25 | 14 | 19454 | 5460 |
HECTD1,CSTPP1,TBC1D19,VCPIP1,CDC23,ANAPC4,NICN1,TPGS2,H1-5,CDC16,TCP1,ANAPC2,DNAJB4,ANAPC16 |
| 3.056e-03 | -5.79 | FAM83G (family with sequence similarity 83 member G) | protein interactions | 644815 | 25 | 14 | 19454 | 5460 |
SMAD3,VIRMA,MOV10,SFN,YWHAG,YWHAH,CSNK1A1L,CRBN,RPA2,VAPB,YWHAZ,SMAD2,CSNK1A1,YWHAB |
| 3.056e-03 | -5.79 | TRIM22 (tripartite motif containing 22) | protein interactions | 10346 | 25 | 14 | 19454 | 5460 |
TAF7,TAB2,CASK,UBE2D1,LGALS8,NFE2L2,TRIM22,CREB1,PML,NFKBIA,EIF4E,RERE,PLEKHF2,LGALS3 |
| 3.056e-03 | -5.79 | PARP9 (poly(ADP-ribose) polymerase family member 9) | protein interactions | 83666 | 25 | 14 | 19454 | 5460 |
ATG16L1,CUL3,IFNGR1,H2BC11,RPA2,RPA3,PML,HSPA8,JAK1,STAT1,STAT2,CGAS,ESR2,JAK2 |
| 3.061e-03 | -5.79 | YEATS2 (YEATS domain containing 2) | protein interactions | 55689 | 159 | 61 | 19454 | 5460 |
TP53INP1,DPY30,CDC23,TAF9,POU5F1,H2AZ1,POLE3,NUP35,SPPL3,HNRNPL,HYPK,WDR37,IKZF5,TP53,PSMC3,CBX3,CDK8,RUVBL2,BAG2,PSME1,POLE4,RAD21,RIGI,RERE,ASF1A,TRIM37,KANSL3,PCBD1,TAF5L,MYC,CDC16,LMO2,TADA1,TADA3,MYO6,TXNIP,ZMYM2,RPL37A,PHF21A,CCNF,CPSF1,MAD2L1,VIRMA,ESR2,ACTB,SNRNP40,SUPT3H,NUFIP2,SUPT7L,RPA2,HSPB2,SQSTM1,DR1,NUP50,RPA3,HCFC2,NLE1,PML,CXXC1,KDM1A,SGF29 |
| 3.062e-03 | -5.79 | FAM210A (family with sequence similarity 210 member A) | protein interactions | 125228 | 30 | 16 | 19454 | 5460 |
CD63,FAM210A,IFT52,SLC1A1,COPE,NPTN,EIF2B5,RAMP3,APEX1,ESR2,BABAM1,LDHB,MGARP,HCST,LCN6,MYL6 |
| 3.062e-03 | -5.79 | TRIM17 (tripartite motif containing 17) | protein interactions | 51127 | 30 | 16 | 19454 | 5460 |
SNX2,LGALS3,UBE2D3,MNAT1,BCL2A1,APEX1,UBE2N,TRIM44,TRAF6,LGALS8,UBE2D1,UBE2H,USP15,HGS,HSP90AA1,UBE2W |
| 3.062e-03 | -5.79 | FBXL2 (F-box and leucine rich repeat protein 2) | protein interactions | 25827 | 30 | 16 | 19454 | 5460 |
UBE2D1,NLRP3,PDE6D,HSP90AA1,CUL2,CSK,PIK3R1,FUNDC1,PIK3R2,UBE2D3,SKP1,SMURF1,HSPD1,FBXO3,SLC6A3,RABGGTB |
| 3.062e-03 | -5.79 | PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta) | protein interactions | 5293 | 30 | 16 | 19454 | 5460 |
IL4,ERAS,GRM2,PIK3R1,TOP3B,DBH,PIK3R3,TNPO2,PTPRZ1,PIK3R2,AKT2,HRAS,MCRIP2,IL3,PIK3CG,IGF1R |
| 3.062e-03 | -5.79 | CRB3 (crumbs cell polarity complex component 3) | protein interactions | 92359 | 30 | 16 | 19454 | 5460 |
TECR,FUNDC2,VTI1B,ANKRD46,PSENEN,RABAC1,STX5,PSMA3,SLC39A9,PARD6A,UBIAD1,PLP2,HMOX2,VAMP1,WDR83,BET1 |
| 3.062e-03 | -5.79 | SYBU (syntabulin) | protein interactions | 55638 | 30 | 16 | 19454 | 5460 |
TRAF7,BLOC1S2,FAM91A1,EXD2,TPH2,RPL29,SNAPIN,POLR1D,MTARC2,EXOC1,RACGAP1,MAPRE1,UBE2H,ARPC3,FBXW11,DISC1 |
| 3.062e-03 | -5.79 | ROMO1 (reactive oxygen species modulator 1) | protein interactions | 140823 | 30 | 16 | 19454 | 5460 |
LDLR,NDUFA4,DVL2,SSBP1,NUP35,ROMO1,SPPL3,TIMM17A,PSMD1,ATG7,ATP5F1A,CIDEB,RPL23,RIT1,SKA3,TAFAZZIN |
| 3.070e-03 | -5.79 | COPII (Coat Protein 2) Mediated Vesicle Transport | REACTOME pathways | R-HSA-204005 | 69 | 33 | 10285 | 3229 |
TRAPPC2L,LMAN1,BET1,SEC13,TRAPPC6A,TRAPPC4,STX5,TRAPPC6B,SERPINA1,YKT6,SEC23A,CNIH1,TFG,SEC22B,GOSR2,PREB,SEC22A,MIR711,SAR1B,CD59,NAPG,CTSC,SCFD1,TRAPPC10,RAB1B,RAB1A,TRAPPC1,SEC22C,TRAPPC3,STX17,FOLR1,NAPA,GRIA1 |
| 3.073e-03 | -5.79 | EDEM3 (ER degradation enhancing alpha-mannosidase like protein 3) | protein interactions | 80267 | 114 | 46 | 19454 | 5460 |
OS9,FIBIN,ERLIN1,LMAN1,DNAJB9,ELSPBP1,SRPRA,STT3A,HSPB1,VCPIP1,P2RY10,EDEM1,CFC1,CALR,PDIA3,EDEM2,ERLEC1,EMC2,ERP29,TMEM87A,HSPD1,SERPINA1,PLD3,NCR3,RPN1,ERLIN2,CBLN4,CLEC2B,PI15,GANAB,GXYLT1,SERPINH1,DNAJC10,SDF2L1,GGH,PSMD1,SEC13,HSPA5,GPIHBP1,EMC1,HSPA8,TMEM106B,LGI1,SSR1,GP9,HSP90B1 |
| 3.073e-03 | -5.79 | HFE (homeostatic iron regulator) | protein interactions | 3077 | 114 | 46 | 19454 | 5460 |
TMEM106A,GLRB,CHST7,TMEM219,SUPT7L,FKBP14,TAPBP,SYVN1,SQSTM1,NXPE3,CYB5D2,B2M,KCNJ8,TAF5L,ENTPD4,PDF,SDF2L1,CGRRF1,LRP12,SENP5,ALG5,DIPK1A,NETO2,B3GALT4,TMEM59L,TFRC,SFTPC,GLCE,RNF167,TUSC3,RAD21,GALNT2,B4GALT7,DAG1,TMEM199,ICAM2,ST6GALNAC3,RPL23,ST3GAL4,BTN2A2,RNF128,FUT1,DIPK2A,ITGA6,CD1A,PXYLP1 |
| 3.073e-03 | -5.79 | DNA strand elongation | REACTOME pathways | R-HSA-69190 | 32 | 18 | 10285 | 3229 |
PCNA,FEN1,MCM4,PRIM2,RPA2,MCM3,RFC4,MCM6,POLD2,RFC5,POLD4,GINS4,RFC2,GINS3,MCM8,RPA3,RFC3,POLA2 |
| 3.077e-03 | -5.78 | fourth_ventricle | COSMIC cancer mutations | fourth_ventricle | 37 | 19 | 16828 | 4835 |
CFC1,CLCN6,GNAQ,IDH1,CFTR,PDIA2,HRAS,KRAS,SMARCB1,FGFR1,TERT,ACVR1,PIK3CA,PTPN11,AKT1,NF2,IDH2,MET,NACC2 |
| 3.088e-03 | -5.78 | ATP metabolic process | biological process | GO:0046034 | 152 | 61 | 18204 | 5365 |
NDUFB5,ATP5F1D,ATP5MC1,ATP5F1E,BAD,NDUFS3,CLPX,ATP6V1A,NDUFB4,GAPDH,AK2,PGK1,ATP5PO,SDHB,LIPA,ATP1B1,AK5,ATP1A2,NDUFB8,BPGM,NDUFA2,SDHC,NUDT5,NDUFS6,NDUFC2,OGDHL,ATP5PF,NDUFB6,PGM1,NDUFV2,IER3,ATP5F1B,NUDT2,ATP5PD,UQCC3,ATP5PB,DNAJC30,STOML2,UCP2,NDUFS2,ATP5MG,NDUFA12,COX11,ATP5MK,NDUFB7,NDUFA5,ATP5MC3,ENO2,PFKFB2,FKRP,NDUFS8,NDUFA1,LDHA,ATP5F1A,NDUFB10,NDUFAB1,PGAM1,ENO1,HTR2A,HSPA8,OLA1 |
| 3.091e-03 | -5.78 | cognition | biological process | GO:0050890 | 319 | 117 | 18204 | 5365 |
TNF,SLC6A3,SLC7A11,KRAS,EP300,CAMK2N1,GRPR,PAK6,PPT1,DBH,ASIC1,EIF4A3,CX3CR1,SLC1A1,CRHBP,OXTR,PPP1R1B,SETD5,MME,SLC6A1,FAM107A,ELAVL4,YTHDF1,CDK5,DKK1,NOG,RP9,DRD3,AGER,ATAD1,PTEN,FOS,SLC11A2,EIF4EBP2,TTC8,ATP8A1,CHRM1,TMOD2,JPH4,VLDLR,SOBP,RAG1,DRD1,JAKMIP1,ADNP,FGF13,TUBA1A,OPRL1,GRIA1,KIT,TACO1,TLR2,TNR,FEN1,PIAS1,PAIP2,CNR1,ATP1A2,PICALM,TUSC3,PAFAH1B1,CHST10,BRINP1,UBE3A,NTF4,CREB1,BGLAP,COMT,ATXN1L,VDAC1,HTR2A,LDLR,LARGE1,ADORA1,ACSS2,SRC,NEUROD2,NETO1,ST3GAL4,CCL11,PRNP,C1QL1,SNAP25,PAK5,DLG4,ARF4,SLC6A4,S100B,TPBG,PAX6,ADCY3,CLN8,CBR3,PDE1B,MECP2,NCSTN,CHMP2B,PTPRZ1,B2M,UCN,CHRNA7,RTL4,CHRNB2,PRRT1,MEF2C,PLCB1,BTG2,TACR1,GPRASP3,KCNK10,NTRK2,SYT4,OPRK1,EGR2,ARL6IP5,PSEN1,PTN |
| 3.096e-03 | -5.78 | MARCKSL1 (MARCKS like 1) | protein interactions | 65108 | 117 | 47 | 19454 | 5460 |
EWSR1,NDUFB5,PAX6,CCAR1,MRPL22,KRAS,TBK1,RAF1,ATP6V1A,RAC2,PTPN1,HRAS,ZBTB2,CAV1,ARF6,CTNNB1,LAMP3,RAB5C,LAMP2,ATP6V1D,RHOG,HSPA8,SOD1,BAP1,RHOU,STX7,CFTR,CDC42,ARL15,LMNA,TRIM24,BCCIP,ESR2,SEC63,ACTB,RALA,DNAJC5,MRPL16,EPS8,RALB,RAB2A,MYC,UBE2H,RMI1,NRP1,BRCA1,RHOB |
| 3.099e-03 | -5.78 | negative regulation of cation channel activity | biological process | GO:2001258 | 49 | 24 | 18204 | 5365 |
MIR1-1,FKBP1B,CRHR1,SRI,SUMO1,MIR448,GPR35,MMP9,CAV1,EPO,FKBP1A,KCNAB1,CLIC2,MIR200C,MIR192,MIR24-1,MIR212,MIR208B,MIR153-1,DRD3,MIR30D,MIR208A,GSTO1,GSTM2 |
| 3.113e-03 | -5.77 | RPSA2 (ribosomal protein SA 2) | protein interactions | 388524 | 150 | 58 | 19454 | 5460 |
SRP14,KRR1,CDR2L,RPS10,HNRNPL,RPS16,LYAR,ST3GAL5,HYPK,DKC1,CDC5L,SURF6,NGDN,CRBN,MPHOSPH10,PPM1B,RPS2,NOL12,RPL31,EWSR1,RPS24,IMP4,RPS13,RPS4X,IMP3,RPSA,TRAPPC13,OR6M1,SDR16C5,FAU,ZNF22,RPS3,SLA2,HEY2,RPS9,SRPK2,NOP16,RPL26,RIOK2,RPS17,ZSCAN25,ZCRB1,RPS5,TADA1,SF3B1,RPS15,YTHDF1,NOP53,MRPS7,AATF,UTP23,RPS14,POLR1D,CDR2,ZNF574,EIF4B,RPL26L1,ZNF770 |
| 3.113e-03 | -5.77 | YLPM1 (YLP motif containing 1) | protein interactions | 56252 | 150 | 58 | 19454 | 5460 |
RIGI,SSRP1,HAPSTR1,TRIM21,RBM3,RINT1,NUPR1,HDAC11,ARHGAP12,SOX2,LGR4,SPG21,RAF1,RBM42,CDC5L,OR8B8,NUP35,TOP1,TSG101,FUBP3,RB1CC1,KPNA1,HNRNPD,ANKRD50,ARMC8,UQCR11,DROSHA,HNRNPA1,ZNF24,WWP2,AIF1,AATF,B9D2,STAU1,ACER3,HSPA8,EP300,RNF113A,SNRPA,RPA3,SIRT7,RPA2,PRMT2,PPP1CB,ATG16L1,SF3A1,WDR77,VIRMA,MATR3,BMP1,PSPC1,CCNF,AR,SNRPB,NONO,PPP1CC,MYC,CUL3 |
| 3.116e-03 | -5.77 | SRCAP (Snf2 related CREBBP activator protein) | protein interactions | 10847 | 120 | 48 | 19454 | 5460 |
SF3A1,ACTL6A,ELP3,RPA2,RPA3,CFDP1,DR1,EP300,NUCKS1,FTL,CREBBP,MYC,MORF4L1,AR,CSGALNACT1,VPS72,MSN,TRIM24,ACTB,MED17,MAD2L1,APEX1,VIRMA,ZNHIT1,TOP3B,ELF1,DMAP1,H2BC1,IK,SMARCB1,PHC1,RUVBL2,H1-6,H3C1,ASF1A,RUVBL1,RIGI,PAX6,ATG9A,HMGA1,DIS3L,AGR2,H2AZ1,THOC2,TOP1,SUMO2,CDK9,NUF2 |
| 3.116e-03 | -5.77 | FNBP1 (formin binding protein 1) | protein interactions | 23048 | 120 | 48 | 19454 | 5460 |
SMC4,GABARAP,BCL6,FGFR1,SF3A1,RND2,CDC42,TUBB,RBBP4,RHOJ,VIRMA,TNPO3,TUBA1B,PTEN,RHOB,H1-10,NTRK3,SMARCA5,RAB11A,RBBP7,KRAS,KPNA2,RUVBL1,WASL,TF,AHCYL1,RIGI,PPP1R12A,RUVBL2,HAPSTR1,MTA2,SMARCB1,RND3,RBPJ,FASLG,ACTR1A,TNPO2,HNRNPL,SPPL3,RHOH,SNX2,CDC5L,DNM2,TNKS,COPS2,RHOG,USP15,DPP4 |
| 3.116e-03 | -5.77 | UBE2D4 (ubiquitin conjugating enzyme E2 D4 (putative)) | protein interactions | 51619 | 120 | 48 | 19454 | 5460 |
HECTD1,RNF7,RNF103,MYLIP,RNF11,RNF5,UBE2D3,TRIM5,RNF10,RLIM,RMND5B,TRIM3,TRIM10,PHF7,MARCHF3,TRIM23,BFAR,UBB,UBTD1,APEX1,TRIM54,SIAH1,TRIM27,TRAF7,STUB1,TOPORS,RNF181,RNF126,ZNRF1,TRIM62,RNF26,RNF115,UFM1,RBCK1,RING1,RNF167,MUL1,TRAF6,RNF14,TRIM8,WWP2,MDM2,UBTD2,ALCAM,TRIM35,MYBL2,TRIM45,RCHY1 |
| 3.116e-03 | -5.77 | COMMD1 (copper metabolism domain containing 1) | protein interactions | 150684 | 120 | 48 | 19454 | 5460 |
CCDC22,BRCA1,TFDP2,COMMD9,FAM107A,CUL2,SUB1,CUL3,CSK,AKT1,RSRC1,NFKBIA,SLC12A2,LMNA,SCLT1,E2F6,NUP62,UPRT,CFTR,COMMD3,CLU,CNKSR3,SOD1,EP300,COMMD2,NMRAL1,SPP1,LYZ,RBM17,NFKB1,GRSF1,ELOC,COMMD5,INSYN1,COMMD6,VPS26C,SPPL3,G6PD,DHX15,TCEAL8,STMN2,TBC1D4,COMMD8,SNAP29,RAD21,SSRP1,CCAR1,ARGLU1 |
| 3.116e-03 | -5.77 | PCBP3 (poly(rC) binding protein 3) | protein interactions | 54039 | 120 | 48 | 19454 | 5460 |
APOBEC3C,ACAA2,HEXIM1,DDIT4L,KLRD1,CFTR,FTH1,UFL1,STAU1,SNRPA,BAP1,SDF2L1,CDC73,THTPA,MYC,GFUS,TYW3,MATR3,PRKCE,ESR2,SRC,B4GAT1,ENO2,NGB,RAB6B,GNPDA2,NUPR1,DDX39A,DCP2,PSMA2,PSMA5,KCTD17,RUVBL1,MEPCE,EIF3E,RUVBL2,SLC39A3,HECTD3,ARL2BP,ECD,TRMT5,TLE1,COMMD5,DDRGK1,PPP1R18,OCRL,ZBTB2,FOLR1 |
| 3.121e-03 | -5.77 | autonomic_ganglia-retroperitoneum-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-retroperitoneum-neuroblastoma | 27 | 15 | 16828 | 4835 |
CTNNB1,MET,KIT,AKT1,JAK2,PTPN11,IDH2,PIK3CA,KRAS,HRAS,IDH1,PIK3R1,GNAQ,MAP2K1,MAX |
| 3.130e-03 | -5.77 | LRRC40 (leucine rich repeat containing 40) | protein interactions | 55631 | 82 | 35 | 19454 | 5460 |
MB21D2,RPL35A,KCTD3,CDC5L,EGLN3,EFHD2,LMBR1L,DNAL1,LRRC57,UBE2H,COP1,CBL,PRMT6,MYC,MTPN,RUNX1,STAU1,HSCB,MEPCE,CNOT6L,LUM,RPA3,BAG2,HSPA8,TLR3,RPA2,EZH2,PIH1D1,TBC1D4,KBTBD4,RAF1,STXBP1,GTF2E2,CNPY3,APOO |
| 3.130e-03 | -5.77 | GINM1 (glycosylated integral membrane protein 1) | protein interactions | 116254 | 82 | 35 | 19454 | 5460 |
RUSF1,BMPR1A,TMX2,GLCE,GALNT12,TPST1,B4GALT7,CLU,RDH11,SAR1B,ADIPOR1,YIPF3,KDELR2,CFTR,GALNT1,TMEM59L,KDELR1,FGFR1,ITGB8,EPO,CTXN1,TFIP11,GCFC2,LDLR,MGAT1,NDFIP1,LMAN1,VAMP7,MICB,RAB5C,RBFOX3,CSGALNACT2,DAG1,FATE1,NRP1 |
| 3.130e-03 | -5.77 | CIAPIN1 (cytokine induced apoptosis inhibitor 1) | protein interactions | 57019 | 82 | 35 | 19454 | 5460 |
ATP6V1D,UBE2H,OSGEP,BOLA1,RB1CC1,BICD2,CHCHD4,HSPB8,RNF40,CUL3,CUL2,ENY2,KARS1,G6PD,MAT2B,EGLN3,TENT5C,STAT1,ATP6V1A,CACNB3,CCNF,RPA2,EEF1E1,RANBP1,MARS1,CAPZA1,DCTPP1,RNF20,STAU1,XPNPEP1,PPP1R2,NUBP2,HSPA8,EWSR1,RPA3 |
| 3.130e-03 | -5.77 | VPS11 (VPS11 core subunit of CORVET and HOPS complexes) | protein interactions | 55823 | 82 | 35 | 19454 | 5460 |
PSME1,STX8,RAB9A,RAB5A,KDM1A,GTF2I,VPS16,STX7,TICAM1,ZNF263,TMEM266,STX17,RNF7,VPS18,VPS33A,RNF181,MID1IP1,MSN,EDNRA,TSG101,TTC9C,ESR2,PARL,STX6,UBE2L3,LRRC61,RAB11A,WWP2,VPS39,GRSF1,MOV10,TRIM32,CCDC92,CSTA,STX1A |
| 3.130e-03 | -5.77 | UBN2 (ubinuclein 2) | protein interactions | 254048 | 82 | 35 | 19454 | 5460 |
RBBP7,H3C1,STAU1,ASF1A,PAX6,RPA3,HIRA,PML,EWSR1,BAG2,RPA2,KLF3,CBX3,CDAN1,SUPT5H,EGR2,POLR1D,SOX9,SPRR1B,HNRNPL,RBBP4,IFI6,SNRNP40,VIRMA,ESR2,LANCL1,FABP5,UBN1,CTTN,CALML5,CSTA,HMGA1,HNF1B,MEF2B,AR |
| 3.130e-03 | -5.77 | TUBA8 (tubulin alpha 8) | protein interactions | 51807 | 82 | 35 | 19454 | 5460 |
MAK16,GABRA1,LGR4,ERLIN2,CFTR,UBL4A,TP53,RPLP0,HEXIM1,MACROH2A2,TFCP2,UBAC2,MAP1B,RPL28,MEPCE,SAR1B,TCP11L2,H1-6,CD81,HDAC6,MYC,RPL7A,DNAJC7,NOL12,H1-1,DNAJB6,SHC1,RC3H2,RBMX2,RPL37A,TRMT10B,RPL8,SPPL3,SIAH1,TCP1 |
| 3.131e-03 | -5.77 | HHV8GK18_gp81 (ORF73) | protein interactions | 4961527 | 123 | 49 | 19454 | 5460 |
H2AC25,HNRNPK,H2AC6,TP53,PPP2R1A,RELL2,ZRANB2,RBPJ,SIN3A,H2AZ1,DPPA2,SUMO2,HMGA1,ELOC,POLB,SNRNP70,ID1,RPA3,HIRA,HCFC2,TWNK,EP300,RLIM,FBXW7,HMGB1,SUMO1,PRMT2,RPA2,WWP1,ADNP,UBN1,LIG3,PARP2,PRMT5,PPP2R5E,ZMAT2,PPP5C,ACAP2,APEX1,CREBBP,PRMT6,CIAO1,MECP2,PIP4K2C,H2AZ2,TDP1,IRF6,ZBTB38,CCDC25 |
| 3.131e-03 | -5.77 | ITPR1 (inositol 1,4,5-trisphosphate receptor type 1) | protein interactions | 3708 | 123 | 49 | 19454 | 5460 |
RAB29,RPA3,DERL1,SGF29,PXMP2,ARHGAP1,ATG16L1,ST7,RND2,OTULINL,CNPY3,SEC62,CDC42,SSR1,CDK1,SDC2,FKBP1A,GTF2H5,FBXL14,SEC61B,VIRMA,HOMER1,CCNB1,AKT1,UFD1,TESPA1,BTF3,BRCA1,VMP1,TMT1A,CAMK2G,FKBP8,AHCYL1,CA8,ERLIN2,DNAJC25,FGL2,CAPZA2,RPN1,STARD13,HOMER3,RAC2,HSD17B11,GRM1,DNAJC1,ERLIN1,BECN1,RHOG,TRPC1 |
| 3.131e-03 | -5.77 | BAD (BCL2 associated agonist of cell death) | protein interactions | 572 | 123 | 49 | 19454 | 5460 |
HNRNPL,SPPL3,SUMO2,AGK,ERLIN1,SYNCRIP,MCL1,BOK,BECN1,AKAP8L,BCL2L1,OSBPL8,HSPB1,PPP3CA,YWHAB,BAK1,YWHAH,YWHAG,S100A10,SMN1,SLC25A10,HSPD1,SLC25A11,EWSR1,MTA2,NDUFA12,APTX,RAF1,PPP2R1A,PRDX2,RBBP4,PRKCE,BAD,PPP2R5E,YWHAZ,PIM2,BAX,AKT1,SFN,PRKACB,BNIP3L,BCL2A1,HSPA8,PMAIP1,PAK5,PRKCA,SLC25A3,CYC1,CDKN1A |
| 3.133e-03 | -5.77 | RNA polymerase II CTD heptapeptide repeat modifying activity | molecular function | GO:0140994 | 17 | 11 | 18094 | 5411 |
CDK8,SSU72,CTDSP2,CDK9,CTDSP1,CDK1,CTDSPL2,DYRK1A,CDK7,RPAP2,CDK12 |
| 3.138e-03 | -5.76 | Alzheimer's disease | KEGG pathways | ko05010 | 165 | 74 | 7161 | 2463 |
UQCRC2,SDHB,COX5A,NDUFC2,PSEN1,COX7B2,COX6B1,RTN4,ATP5MC3,ATP5F1E,NDUFA2,NDUFB4,ATP5PB,CAPN2,FAS,ATP5PF,PPP3CA,PPP3R2,NDUFB10,MME,HSD17B10,NDUFB6,NDUFV2,PSENEN,BACE1,CYC1,UQCRH,ATP5F1B,COX6C,ATP5F1D,PSEN2,COX7A1,IDE,GNAQ,NDUFA5,CAPN1,CALML5,COX4I1,COX7B,NDUFB5,CDK5R1,TNF,BAD,NDUFA12,NDUFA4,IL1B,NDUFAB1,COX8A,NDUFS6,CASP12,NDUFB8,ATP5PO,SDHC,NDUFS3,ATP5PD,ATP5MC1,COX6A2,GAPDH,NCSTN,NDUFS2,PLCB1,NDUFB7,CDK5,UQCR11,ATP5F1A,NAE1,UQCRQ,NDUFA1,NDUFS8,APH1A,COX4I2,PLCB2,UQCRC1,COX6B2 |
| 3.138e-03 | -5.76 | Alzheimer's disease | KEGG pathways | hsa05010 | 165 | 74 | 7161 | 2463 |
HSD17B10,MME,NDUFB10,PPP3R2,UQCRH,CYC1,BACE1,PSENEN,NDUFV2,NDUFB6,PSEN2,ATP5F1D,COX6C,ATP5F1B,COX4I1,CALML5,NDUFA5,GNAQ,CAPN1,IDE,COX7A1,NDUFC2,COX5A,SDHB,UQCRC2,RTN4,COX6B1,PSEN1,COX7B2,NDUFB4,ATP5PB,NDUFA2,ATP5F1E,ATP5MC3,PPP3CA,ATP5PF,FAS,CAPN2,PLCB1,NCSTN,NDUFS2,GAPDH,COX6A2,ATP5MC1,NDUFA1,UQCRQ,NAE1,ATP5F1A,UQCR11,CDK5,NDUFB7,COX4I2,APH1A,NDUFS8,COX6B2,UQCRC1,PLCB2,COX7B,IL1B,NDUFA12,NDUFA4,TNF,BAD,CDK5R1,NDUFB5,NDUFB8,CASP12,COX8A,NDUFS6,NDUFAB1,ATP5PD,NDUFS3,SDHC,ATP5PO |
| 3.142e-03 | -5.76 | ANP32A (acidic nuclear phosphoprotein 32 family member A) | protein interactions | 8125 | 126 | 50 | 19454 | 5460 |
PGR,FZR1,SUMO2,SRP14,KPNA1,DRG1,PPIB,XPO1,E4F1,PDIA3,PGAM1,MEPCE,SSRP1,SAR1B,ANP32B,EIF3E,AHCYL1,TRIM26,H3C1,PSMA1,KRAS,HAPSTR1,MAP1B,EZH2,DMAP1,ACTR2,SOX2,H2AX,E2F4,APEX1,ACTB,B4GALT3,VPS72,EIF4A3,KPNA6,MYC,CUL3,B9D2,ARHGEF39,NSFL1C,PSMA3,DERL1,SOD1,PEBP1,BAP1,ELOVL1,UBE2M,OXSR1,RPA2,PPARG |
| 3.142e-03 | -5.76 | GPAT4 (glycerol-3-phosphate acyltransferase 4) | protein interactions | 137964 | 126 | 50 | 19454 | 5460 |
AQP3,RPN1,STIM1,MGARP,DNAJC25,TP53,TOP3B,MSH6,LRRN4CL,TSPAN17,TMT1A,ESYT1,RHOG,RAB5C,MOV10,RAMP3,TES,RAC2,STARD3NL,HSD17B11,PTPN1,GPR35,GP9,FEM1A,SSR1,CTDSP1,ST7,KLRD1,SEC62,CDC42,RND2,OTULINL,PXMP2,LPAR1,HSCB,DERL1,VIPR1,SYVN1,TSPAN15,RPA3,LMNB1,ATP1A3,SYP,CIAO1,CHP1,APLNR,SLC1A1,SEC61B,GPR173,CDIPT |
| 3.145e-03 | -5.76 | MAB21L2 (mab-21 like 2) | protein interactions | 10586 | 141 | 55 | 19454 | 5460 |
GTF2I,NPM3,COIL,G3BP2,PACSIN3,DDX46,RPA2,MAP2K1,KLC2,TFIP11,PRKCA,SPTBN1,EEF1E1,EDF1,CDC20,SRPK2,PNMA1,CREB1,RTRAF,AP2M1,RPS26,RPF2,CFL2,RACGAP1,CEP70,NONO,DHX16,G3BP1,TOM1,SSRP1,PRPS1,POLDIP3,RBM3,PRPSAP1,CTNNA2,AP1S2,MIEF1,WBP11,EIF2S1,INA,FCHO2,KCTD10,TMPO,NUP35,CDC5L,SYNCRIP,SMCHD1,ESYT1,HNRNPD,PDAP1,KARS1,RBM17,PPFIBP1,YWHAG,DDRGK1 |
| 3.145e-03 | -5.76 | BRLZ | smart domains | SM00338 | 51 | 23 | 9717 | 2575 |
FOSL2,CREB3,DDIT3,ATF3,CREB1,FOS,ATF4,JUNB,MAFG,BATF,CEBPE,NFIL3,CEBPG,ATF1,JUN,NFE2,NFE2L2,CREB3L4,XBP1,BACH1,HLF,NFE2L1,TEF |
| 3.146e-03 | -5.76 | positive regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032725 | 15 | 10 | 18204 | 5365 |
IL1B,IL12B,IL18,RIGI,CD80,LILRA2,IL23A,SYK,PAEP,TLR9 |
| 3.147e-03 | -5.76 | EHD2 (EH domain containing 2) | protein interactions | 30846 | 65 | 29 | 19454 | 5460 |
HRAS,EEF1AKMT3,EHBP1,AP2M1,RAC2,KCTD15,TAGLN2,RHOJ,CGAS,CDK9,CCT7,PIK3R3,RHOG,RHOB,DNAJB6,EHD4,CCT8,PICK1,BPGM,DHX16,FBXW7,AP1M1,E2F4,CDC42,PPP2R1A,EHD1,EHD3,NEK7,PICALM |
| 3.147e-03 | -5.76 | CCL5 (C-C motif chemokine ligand 5) | protein interactions | 6352 | 65 | 29 | 19454 | 5460 |
CCL17,NTMT1,CXCL9,FZR1,CXCL11,CXCL14,PHB1,SDC4,PTPN1,CCL25,CCL28,CCL5,CCL11,CCL24,CXCL12,DPP4,CCR3,CCR4,CXCL10,CCL2,KRAS,CCL27,CCR5,CCR1,CCL21,SPRYD4,CXCL8,CCL20,XCL1 |
| 3.147e-03 | -5.76 | CEP170B (centrosomal protein 170B) | protein interactions | 283638 | 65 | 29 | 19454 | 5460 |
CAMSAP2,YWHAB,MAPRE1,BICD2,YWHAZ,NTAQ1,YWHAH,INSYN1,YWHAG,NDC80,SFN,SLMAP,EGLN3,ESR2,HNRNPL,RPGRIP1L,GSK3A,TRIM36,TUBB4B,PNMA2,ACTR1A,KIF2A,TOP3B,TP53,PCGF6,FBXW7,TRIM37,LCA5,ZYX |
| 3.147e-03 | -5.76 | PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1) | protein interactions | 57580 | 65 | 29 | 19454 | 5460 |
AKT1,QPCTL,PPIB,PSMD7,NME2,DTL,PSMB5,PSMA6,PHB1,SSBP1,PSMB1,RHOH,ESR2,VIRMA,PIP5K1A,TOP3B,STXBP1,CDC42,ATP5PO,RPA2,GID8,NLE1,NCDN,RFC4,FAF1,RPA3,KRAS,SKP1,UTP25 |
| 3.147e-03 | -5.76 | MED13L (mediator complex subunit 13L) | protein interactions | 23389 | 65 | 29 | 19454 | 5460 |
RPAP2,MED30,SOX2,FBXL19,TOP3B,MED9,POLR2G,POLR2C,MED31,CDK8,MED23,HAPSTR1,MED11,FBXW7,AR,MED22,ZDHHC15,MED4,UBE2H,MED27,MED21,MED10,MED29,SYNCRIP,POLR2B,VIRMA,ESR2,MED17,POLR2I |
| 3.151e-03 | -5.76 | EXOC1 (exocyst complex component 1) | protein interactions | 55763 | 138 | 54 | 19454 | 5460 |
RPA2,GOLGA5,GIT2,HECTD1,ATG16L1,KDM1A,STAU1,RPA3,CXCR4,HSPA8,STXBP6,EXOC8,CCHCR1,RALB,TRIM32,MYC,GPR17,RAB11A,EXOC5,THAP7,RALA,APLNR,VIRMA,ESR2,S100A6,CCSER2,SCN2B,SYBU,PHF21A,EXOC3,CA14,TFRC,DISC1,CCDC122,SNAP29,IL1R2,JUN,SNAPIN,KRAS,TMED1,SIKE1,BLOC1S2,EXOC2,MED4,RB1CC1,KXD1,NDC80,DDRGK1,VTI1B,SPTAN1,NUF2,CDC5L,CD274,HRAS |
| 3.152e-03 | -5.76 | autophagosome organization | biological process | GO:1905037 | 84 | 37 | 18204 | 5365 |
RAB23,ATG4A,ATG16L1,STBD1,ATG3,GABARAPL1,TP53INP1,RAB1A,VMP1,MAP1LC3A,UBXN2B,RAB33A,TP53INP2,TOM1,ATG101,RAB33B,GABARAPL2,ATG7,SMURF1,RB1CC1,TRAF6,STX12,RAB1B,EMC6,BAG3,MAP1LC3B,NSFL1C,BECN1,GABARAP,STX17,WDR45,RAB19,CTSD,ATG9A,PSEN1,MTM1,ATG4C |
| 3.153e-03 | -5.76 | TCF20 (transcription factor 20) | protein interactions | 6942 | 132 | 52 | 19454 | 5460 |
CPSF1,ZNF330,EIF4A3,TRIM27,RBBP4,SNRNP40,VIRMA,ESR2,APEX1,MYC,AR,PDCD4,RPA3,DVL2,SIRT7,NUP50,NUCKS1,COIL,RPA2,PAX9,SIN3A,H2AZ1,GYS1,SLC39A10,MIF,TOP1,NOP9,ZBTB2,NUP35,HMG20A,HMGA1,IRF4,YWHAH,H2AC4,POU5F1,TOPBP1,EWSR1,BAG2,RBBP7,ASF1A,MDC1,MTA3,E2F4,SUPT5H,JUN,SOX2,SMAD1,RPS7,CBX3,NFE2L2,H2BC1,MTA2 |
| 3.153e-03 | -5.76 | PLIN3 (perilipin 3) | protein interactions | 10226 | 132 | 52 | 19454 | 5460 |
MTCH2,MIEF1,MAX,ANP32A,EEF1A1,GDI2,EZH2,RAD23B,ABHD4,AAMP,SYNGR3,MTMR2,RUSF1,RAB1A,GAD2,VDAC1,IMPA2,SFT2D2,FAM20C,ANKMY2,BTF3L4,SHC1,SRP14,RPRD1A,IGBP1,SNX2,SNX1,RAB1B,ABHD5,MAP2K1,ZER1,PIH1D1,TBC1D13,BAP1,RPA3,RAB9A,STAU1,GPC1,DHPS,MYC,RHOBTB3,JPT1,BRCA1,SYP,CALU,SMAD2,EIF4A3,SYNGR1,CYBC1,LGALS3,VIRMA,MYG1 |
| 3.153e-03 | -5.76 | CPS1 (carbamoyl-phosphate synthase 1) | protein interactions | 1373 | 132 | 52 | 19454 | 5460 |
MALSU1,RAMP3,TOMM70,FAHD1,TES,YBEY,PHB1,DEFB121,CBL,DNAJC7,MRPS26,TMEM70,TUBG1,HDAC6,ASB1,FAM174A,RAD21,IMMP2L,EMC2,HSD17B10,SLC25A10,MAP1B,AP1S2,CHMP4C,DMAP1,H2AX,RAF1,B3GNT2,VIRMA,ARMC6,MRPL23,ALB,UBE2H,HTRA2,ATP1A1,MRPS25,MRM2,LMO2,MTG2,MYC,HSPA5,FBXL4,EMC1,THBS3,HSPA8,BAP1,MAIP1,PIH1D1,ACAA2,METTL14,LDHAL6B,SEC22B |
| 3.153e-03 | -5.76 | DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13) | protein interactions | 23317 | 135 | 53 | 19454 | 5460 |
VIRMA,ESR2,OGN,LRIF1,TAX1BP1,LGALS3,MANSC1,IRF2BP1,PHF21A,SCAMP2,STUB1,UBE2H,FTSJ3,LGALS8,TRIM23,LAMTOR1,CUL3,TBCE,RAB11A,MLF1,MYC,STAU1,FBXW7,KDM1A,RAB9A,HSPA8,CLK1,SLC39A9,FGFR1,NOP9,CGAS,SNX1,AFTPH,HNRNPL,ATP6V1A,RNF128,HSPB8,WWP2,LAMP2,RIGI,PHF1,BAG2,BSCL2,GADD45A,TBC1D4,RAB4A,EZH2,RPL15,LGR4,SOX2,ARFGEF1,CCT5,JPH4 |
| 3.158e-03 | -5.76 | cytoplasmic side of plasma membrane | cellular component | GO:0009898 | 160 | 63 | 19108 | 5553 |
LITAF,CACNB4,GNG11,GNB4,STAC3,EFCAB7,RGS2,GNG3,TRAF6,JUP,GNG10,JAK2,PTPN22,PPP3CA,GNA14,SOCS3,BIRC2,CYTH1,GNG12,PKP4,MYD88,KRAS,RGS1,GNAQ,G6PD,LILRB4,GNA11,CD2,MIEN1,SNX5,KIT,GNAI2,GNG13,TIRAP,TRAF2,JAK1,C2CD2L,KCNAB1,PTEN,PTPN4,GNG5,GNAO1,GNAI3,HTRA2,RACGAP1,CHMP4C,GNG2,DLG1,SNX18,AP2A1,TRAF1,GNGT2,TRAF3IP2,FERMT2,AP2M1,IKBKB,GNG7,GNAZ,AP2S1,GNB3,DLG4,GNB1,S100A6 |
| 3.158e-03 | -5.76 | methylosome | cellular component | GO:0034709 | 13 | 9 | 19108 | 5553 |
ERH,SNRPD2,SNRPB,PRMT5,WDR77,SNRPD3,SNRPD1,SNRPE,SNRPG |
| 3.161e-03 | -5.76 | TOM complex | cellular component | GO:0140596 | 7 | 6 | 19108 | 5553 |
TOMM7,TOMM40,TOMM20,TOMM22,TOMM6,TOMM70 |
| 3.161e-03 | -5.76 | prefoldin complex | cellular component | GO:0016272 | 7 | 6 | 19108 | 5553 |
PFDN1,PDRG1,PFDN5,PFDN2,PFDN4,PFDN6 |
| 3.161e-03 | -5.76 | mitochondrial permeability transition pore complex | cellular component | GO:0005757 | 7 | 6 | 19108 | 5553 |
BAX,PPIF,SLC25A4,SLC25A5,VDAC1,SLC25A31 |
| 3.161e-03 | -5.76 | PTW/PP1 phosphatase complex | cellular component | GO:0072357 | 7 | 6 | 19108 | 5553 |
PPP1R10,PPP1R12A,WDR82,PPP1CB,TOX4,PPP1CC |
| 3.161e-03 | -5.76 | Lsm2-8 complex | cellular component | GO:0120115 | 7 | 6 | 19108 | 5553 |
LSM3,LSM8,LSM4,LSM6,LSM5,LSM2 |
| 3.164e-03 | -5.76 | anaphase-promoting complex | cellular component | GO:0005680 | 22 | 13 | 19108 | 5553 |
ANAPC13,ANAPC15,CDC23,ANAPC11,CDC20,MAD2L2,ANAPC4,UBE2S,ANAPC2,CDC16,CDC26,ANAPC16,FZR1 |
| 3.164e-03 | -5.76 | U5 snRNP | cellular component | GO:0005682 | 22 | 13 | 19108 | 5553 |
SNRPD1,TXNL4A,CD2BP2,SNRPB,SNRPD3,PRPF18,SNRPE,SNRPG,SNRPN,SNRNP40,SNRPD2,DDX23,TSSC4 |
| 3.166e-03 | -5.76 | Gastrin-CREB signalling pathway via PKC and MAPK | REACTOME pathways | R-HSA-881907 | 443 | 166 | 10285 | 3229 |
PSMD10,FRS3,DUSP9,SRC,XCL1,CHRM5,FGF10,RAP1B,F2,PRKCQ,KRAS,P2RY11,MAP2K1,WDR83,GNB1,UBA52,RGS2,FGF22,GNA11,RAF1,RASGRP2,GNRH2,GRM1,PIK3R2,IL2RG,LPAR1,YWHAB,LPAR6,PPP2R5A,FGF1,DUSP6,PAQR3,GNG5,PLCB1,MET,PSMA5,GNG10,FGF23,PPP2R5E,GNG13,SPTAN1,HTR2A,PSMB3,PEBP1,GNRHR2,SHC1,RASGRP3,OXTR,CHRM1,PSMB4,SEM1,DUSP1,PSMC3,UTS2R,PSMA1,MLN,IL3,RPS27A,SPRED1,PSMD4,PHB1,FGF16,LAMTOR3,CAMK2G,GRPR,IL2RB,GNRH1,VWF,PSMC1,CUL3,IL5,HRAS,GNG11,LAMTOR2,KIT,PPP2CB,GNA14,PSMD1,PSMB2,PEA15,PSMA6,P2RY10,PIK3CA,PPP5C,GPR65,SPTBN1,ANGPT1,PSME1,GNG12,AVPR1B,GNG2,FGF17,PSMD7,HCRT,PSMD14,GNG7,CHRM3,PRKCA,PPP2R1A,UBB,RGS19,JAK2,PSMB7,PSMD3,CREB1,PSMB1,NPSR1,NMBR,PIK3R1,PSMB5,PSMA3,TAC1,PSMC4,UTS2,P2RY1,PSMA4,PSMB10,MCHR2,TACR1,FGFR1,IL2,PSMC5,PSMB11,ABHD6,PSMB6,PROK1,PSMA2,PTGFR,BRAP,PLCB2,CSK,BRS3,DLG4,PSME2,FGF3,ABHD12,CCL23,HBEGF,MCHR1,PSMD6,SPRED2,IL2RA,PSMB9,MAP3K11,GPR17,EDNRA,GNB4,ADRA1A,NEFL,DUSP10,TACR3,GHRL,CSF2,PIK3R3,PRKCE,GNB3,GNGT2,FGF7,PTGER1,JAK1,PSMD12,GNAQ,LPAR2,SHC3,GNG3,RAP1A |
| 3.168e-03 | -5.75 | skin-back-benign_melanocytic_nevus | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus | 11 | 8 | 16828 | 4835 |
KRAS,CTNNB1,GNA11,HRAS,KIT,GNAQ,STK11,PIK3CA |
| 3.168e-03 | -5.75 | skin-scalp-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-scalp-malignant_melanoma-lentigo_maligna | 11 | 8 | 16828 | 4835 |
PIK3CA,STK11,GNAQ,PTEN,HRAS,KIT,KRAS,CTNNB1 |
| 3.174e-03 | -5.75 | liver-other-hepatoblastoma | COSMIC cancer mutations | liver-other-hepatoblastoma | 32 | 17 | 16828 | 4835 |
TERT,PIK3CA,SMARCB1,MET,CTNNB1,TP53,SRSF2,PTPN11,AKT1,CDKN2C,GNAQ,SF3B1,NFE2L2,HRAS,KRAS,PIK3R1,IDH1 |
| 3.174e-03 | -5.75 | hepatoblastoma | COSMIC cancer mutations | hepatoblastoma | 32 | 17 | 16828 | 4835 |
NFE2L2,SF3B1,GNAQ,IDH1,PIK3R1,KRAS,HRAS,SMARCB1,PIK3CA,TERT,AKT1,CDKN2C,PTPN11,SRSF2,TP53,CTNNB1,MET |
| 3.176e-03 | -5.75 | regulation of gliogenesis | biological process | GO:0014013 | 112 | 47 | 18204 | 5365 |
KRAS,TNF,CERS2,ASPA,DLX1,TP53,NKX6-2,CTNNB1,ID4,IL6,MIR142,LDLR,DAG1,IL1B,IL6ST,PRMT5,CXCR4,NOG,DUSP10,GPR37L1,VEGFC,DRD3,IL34,MYRF,MIR181C,MECP2,LTA,PTPRZ1,PPP1CC,NF2,ZNF365,EZH2,RB1,NR2E1,TNFRSF1B,TSPO,TLR2,MIR222,RHEB,UFL1,F2,MIR221,DICER1,RNF10,PTN,EGR2,MIR146A |
| 3.176e-03 | -5.75 | negative regulation of lipid metabolic process | biological process | GO:0045833 | 112 | 47 | 18204 | 5365 |
CCDC3,SNAI2,CYP7A1,HCAR1,CNR1,DCAF5,SOD1,GFI1,NR0B1,ORMDL1,FMC1,BRCA1,SOX9,MIR206,MIR342,PPP2R5A,BSCL2,NFKB1,ERLIN1,DKK3,APOC2,MIR204,CYP27B1,MIR98,FBXW7,ETFBKMT,INSIG2,KLHL25,PROX1,PIK3CG,UGT1A1,CH25H,ORMDL3,IL1B,ADORA1,FMO1,MIR132,AKT1,MIR1-1,ATP1A1,CDK8,MIR9-1,TNF,FMO2,ERLIN2,MIR192,MIR185 |
| 3.184e-03 | -5.75 | CALM1 (calmodulin 1) | protein interactions | 801 | 607 | 201 | 19454 | 5460 |
H2AX,ESS2,KIF1C,NUPR1,TBC1D4,GFM2,DISC1,TFCP2,PIK3CA,GAD2,IDH1,ATP2B4,ZNF451,FKBP8,RAB3B,TPM3,API5,CSNK2A1,PGAM1,RIT2,SNRNP70,LY96,NUDT9,ADD1,ARMC1,UBE2N,ITGA6,CDC5L,MIF,CFTR,CDC42,DDIT4L,SCLT1,UBE2M,RPRD1B,SDCBP,PGK1,PML,BAP1,RGS2,STK38,PHKA1,ARHGAP21,KCNQ5,MORF4L1,AKT1,KCNB1,UBE2H,CRHR1,SNTA1,SGTA,QSER1,SEC61A1,CSNK2B,SRC,RALA,DAPK1,FAM83C,PDHA1,EWSR1,MYO1B,S100B,ZBED1,KRAS,GJB1,EPHA4,PHKG1,DDRGK1,NT5C2,CTNNB1,PPIB,WWP2,YWHAB,CBL,FKBP4,VAMP7,SUMO2,TOM1L2,SYK,PIH1D1,DDX5,YAF2,SF3B1,FOS,RPS28,FLYWCH2,PEBP1,DDX39B,ADRB2,EMC1,TBC1D1,BTF3,MYC,PDF,PHKB,FAM83B,DLST,APEX1,ESR2,POLR2B,USP16,MATR3,HINT3,RAD23B,ACTR2,JOSD1,CAMK1,STX8,ABHD10,ADD2,TOM1,HSPE1,HUWE1,CAMK2G,CDC37L1,CALR,MOV10,PDE1A,SPP1,TCEAL8,RCHY1,SRP14,CDK9,RGS10,RS1,DCUN1D1,CCNA2,EDF1,TPT1,DDAH1,CCND1,RPS14,KCNH1,NOL7,CHMP1A,STOM,HSP90B1,COX6C,JUP,SQSTM1,VIPR1,HMCES,GID8,ZKSCAN1,SOD1,FBXO9,EIF5B,GTF2I,AR,RALB,MAPRE1,CDC73,PTEN,TRIM24,METAP2,ENO1,MRPL53,CCNF,OPTN,CEP97,RPL22,YES1,RPL13A,ASPM,DLG3,RAF1,ANP32A,EZH2,VAMP2,UBE3A,ANP32B,PSMD12,NRGN,TNF,PDIA3,PRDX1,ZBED4,PPP3CA,BCL2L1,RPL23,CETN3,CETN2,HYPK,DUSP22,PRDX3,PPP1CB,MYL6,ATP5IF1,FBXO30,NT5C3A,OPRM1,CUL3,FMC1,SP1,HSP90AA1,YWHAZ,MYO6,FAS,SEC61B,SNRPB2,JAK2 |
| 3.202e-03 | -5.74 | positive regulation of mitotic cell cycle | biological process | GO:0045931 | 132 | 54 | 18204 | 5365 |
CDC7,MIR495,FGFR1,CDK1,AKT1,PTPN11,POLDIP2,NKX3-1,MTA3,PHB2,VPS4B,MDM2,DTL,TTL,PAFAH1B1,CDC23,DUSP3,CDC16,UBE2E2,TMOD3,FGF10,USP2,EIF4E,CCND3,RAB11A,ADAMTS1,CDC20,CUL3,MIR214,PRKCA,PLCB1,MIR208A,SMARCD3,MIR222,RGCC,MIR221,AIF1,LSM10,CCND1,MIR519D,CDK4,PPP1R10,CYP1A1,CCNB1,SIN3A,MEPCE,WNT10B,RRM1,ANAPC11,TERT,MAD2L1BP,DYNLT3,RB1,MIR29A |
| 3.204e-03 | -5.74 | MYO1B (myosin IB) | protein interactions | 4430 | 249 | 90 | 19454 | 5460 |
GAMT,PPP1CB,FBXO30,UFL1,HACD1,FOS,TMEM106B,DDX39B,ZMPSTE24,CDKL2,NTRK3,SP1,BTF3,CUL3,MYC,PPP1R3C,ACTB,EIF4A2,STAT1,DKK3,DLST,PDHA1,EZH2,H1-3,SOX2,ACTN4,ISG15,TOP3B,RAF1,FLOT1,TRIM37,PSMA1,EPHA4,TNF,KRAS,ZYX,AGR2,CTNNB1,BCL7C,CHMP2A,EGLN3,TMOD1,HSP90B1,RPA2,CFTR,AATF,HSPA5,FBXW7,SQSTM1,SIRT7,RPA3,BAP1,UBE2H,EPHA2,ATP1A1,SPOP,USP14,PPP1CC,AR,AKT3,SRPK2,VIRMA,SH3BGRL,CTSB,DAPK1,MGST3,PTEN,MOB4,CTTN,CCNF,FURIN,CAPZA2,PIK3CA,TFCP2,MAP1LC3B,FBP1,DUSP21,FBXO25,CAMK2G,STYK1,ECD,HDAC6,CSNK2A1,COPS5,DPP4,TMPO,STX6,RAC2,COX4I1,EEF1AKMT3 |
| 3.207e-03 | -5.74 | cellular component disassembly | biological process | GO:0022411 | 359 | 130 | 18204 | 5365 |
SSRP1,ATG7,SMARCD3,GABARAPL2,CHMP5,LIX1,TFIP11,CHMP4C,DSTN,RETREG1,STX17,UFL1,STMN2,RPL23,MMP20,ATG9A,FUNDC2,MCOLN1,FBXO7,CHMP2A,FURIN,SMARCB1,CCSAP,CHMP2B,CMA1,CAPG,SNAPIN,VRK1,GABARAPL1,VTI1B,TRIP4,RAC2,RB1CC1,VPS33A,CDK1,HSPA8,MAP1LC3B,CHMP1B,RRP7A,SNAP29,PHB2,CFL1,MAP4,SQSTM1,TRIM21,WDR45,SMARCE1,FLOT1,ACVR1C,STX5,PAFAH1B1,TP53,RNF14,MMP14,EPHA4,BMERB1,LAMP2,MYC,GFM2,RCHY1,USP30,CHMP1A,VPS4A,FAF2,MMP9,CFL2,NFE2,PRKCA,VTA1,MTRES1,EIF4E2,VPS16,AKAP8L,DICER1,FIS1,NAPA,VPS54,EXOC8,RIMOC1,BECN1,SNAI2,RETREG2,ATG4C,KIF2A,PYM1,UFM1,MTRF1,H2AC25,TSG101,PELO,ATG3,RETREG3,PRKCB,TAFAZZIN,MAP1LC3A,CDK5RAP3,BLCAP,VIPAS39,ABCE1,LCP1,DFFA,C1QC,H2BC1,VAMP8,EIF2D,DKK1,DDIT4,HDAC6,GABARAP,VPS4B,PLG,PRSS1,FUNDC1,PLAAT3,APEH,HMGA1,ATG4A,DDRGK1,BOK,SKIC8,CX3CL1,CX3CR1,VMP1,CTSK,SNX14,KLK5,TEX264,ETF1,FBXL4,VAMP7 |
| 3.212e-03 | -5.74 | negative regulation of protein phosphorylation | biological process | GO:0001933 | 292 | 108 | 18204 | 5365 |
SOCS3,MIR137,PAX6,CAV1,NF2,CEP85,UBASH3B,CAV3,PKIG,CNKSR3,CDKN1B,SOCS5,IMPACT,MIR711,MIR218-1,NTRK3,PPARG,IGFBP3,SFN,MIR212,MIR146A,PSEN1,PAQR3,LILRB4,DNAJC3,MIR106B,TAF7,YWHAG,FKBP8,IFNG,PDCD4,BAX,RTRAF,SFRP1,PPIA,MIR34A,GNAQ,HSPB1,DUSP19,MIR15A,PTPRQ,INPP5K,PTPN1,MIR132,ERRFI1,ANGPT1,SPRY1,HEXIM1,SOCS4,PRNP,ZBED3,THY1,CTDSP2,PARD6A,TRIM27,PTEN,DUSP6,TSG101,PKIB,CDKN1A,LRP6,MACROH2A1,CDK5RAP3,TESK1,DEFB114,RB1,ADNP,MIR20A,RGN,GSKIP,CAMK2N2,GADD45A,PID1,CBL,CTDSP1,PAK2,IL2,SLC8A1,TRIB1,CRKL,CAMK2N1,DBNDD1,ADIPOQ,SPRED1,DUSP3,CHP1,MIR24-1,DUSP22,BAK1,HYAL2,GSTP1,SPRED2,DUSP1,NCK1,CORO1C,PTPN22,DNAJC10,AKT1,DKK1,HEXIM2,RGS2,IL1B,PRR5L,PKIA,C9orf72,PYCARD,DUSP10,STK38 |
| 3.215e-03 | -5.74 | vesicle targeting | biological process | GO:0006903 | 65 | 30 | 18204 | 5365 |
PSEN1,TRAPPC1,TMED9,TRAPPC2L,PREB,EXOC8,SNAP29,TRAPPC3,EXOC5,EXOC3,EXOC1,TRAPPC10,TRAPPC13,CUL3,SNAP23,WDR11,CEP19,YKT6,TRAPPC6A,TRAPPC4,FAM91A1,NLGN1,TRAPPC6B,EXOC2,SAR1B,ARFGAP3,STARD3NL,KLHL12,AP1AR,TFG |
| 3.215e-03 | -5.74 | membrane biogenesis | biological process | GO:0044091 | 65 | 30 | 18204 | 5365 |
CHMP5,NSFL1C,NLGN2,CHMP1B,TLCD2,HDAC3,EMP2,REEP4,FLOT1,BANF1,CHMP4C,CLIP3,S100A10,VPS4B,UBE2I,TLCD1,CAV2,NLGN1,CAV1,PTEN,SPTBN1,REEP3,CHMP2A,CAV3,CHMP1A,UBXN2B,SERINC1,UGCG,VPS4A,CHMP2B |
| 3.216e-03 | -5.74 | dendritic tree | cellular component | GO:0097447 | 622 | 212 | 19108 | 5553 |
THY1,FCGR2B,RBM3,HOMER3,SLC32A1,GNG3,KCNC1,CDK5R1,ALCAM,SYNDIG1,COMT,MAX,SLITRK2,SYT4,SLC6A6,HTR5A,HTR1F,ELAVL4,ZC3H14,ASIC2,OPRK1,CTTN,PRNP,ATF4,PPP2R1A,YKT6,ABHD13,BRINP3,CLU,TMEM108,PDE4B,HSP90AB1,ERO1A,GABRG2,PCSK2,TRIM3,FUBP3,LYNX1,SLC4A10,GLRX2,SRSF10,AMIGO1,MME,C9orf72,NDFIP1,GRM2,NLGN1,KIF1C,RCVRN,SLC8A1,NLGN2,RIT2,HRH3,PDLIM4,BRINP2,CACNG3,HTR1A,FGF13,CHRM3,GNAZ,HRH2,SLC4A8,CDK5,SLC1A1,KCNJ2,STAU1,GPHN,HOMER1,CHRM5,L1CAM,SRC,FEZ1,CRYAB,NTF4,GABRA1,CTNND1,RAB27A,TMEM266,DRD1,ELK1,GNAI2,BGLAP,KCNH1,TRAK2,MOB4,IL6ST,MAP1B,GLRX5,ATP6AP2,FZD3,GNAO1,STAT1,TMEM185A,KIF3B,ABITRAM,CD2AP,GRM1,NTRK2,PPFIA2,HSPA8,GPR37,BACE1,UHMK1,KPNA1,NQO1,LRRC4,CHRM4,CHRM1,ADORA3,PPP1CC,IFT52,RPL28,SLC38A2,PSEN1,ATXN1L,LYPD6,CASC3,LHFPL4,CAPN2,SNX14,CPEB1,LAMP5,PPP3CA,ELFN1,TIAM1,ATP1A2,KCND2,CDC42,NEGR1,ATXN10,GLRB,RGS7BP,MAP1S,NSG1,OPRM1,GCHFR,TXNRD2,KCNA2,PTEN,BECN1,IGF2BP1,SARM1,LPAR1,KLHL1,OPHN1,SIPA1L1,BMPR1A,PDYN,ABHD17A,KCNIP2,BMPR2,MTMR2,GRIA2,CLSTN3,RAB5A,CCN3,SOD1,UCN,ABHD12,GRIA1,MT3,GSK3A,GNB3,BRINP1,DRP2,CCR2,HDAC6,FZD4,PSD2,BMPR1B,PPT1,DYRK1A,CRHBP,EPHB6,HPCA,CAMK2N1,CX3CR1,AZIN2,JPH4,KCND3,TACR1,CPLX2,P2RY1,IFT57,TACR3,GNG13,BAG2,GABBR1,ADNP,LRFN3,HSP90AA1,PRSS12,TPBG,GLRA1,PNOC,NCDN,ROGDI,EPHA4,LGI1,GPM6A,NGDN,GABRA2,CTTNBP2,ARF4,ADCY2,ADORA1,EIF4A3,HTR2A,USP8,TRAPPC4,KCNB1,DLG4 |
| 3.224e-03 | -5.74 | ceramide biosynthetic process | biological process | GO:0046513 | 57 | 27 | 18204 | 5365 |
TLCD3B,ST8SIA4,SPTSSB,B3GALT1,B3GALT4,B4GALT6,ST3GAL2,CYP4F22,AGK,GAL3ST1,ST3GAL5,SGMS2,B4GALT3,SPTSSA,B3GALT2,ELOVL1,DEGS1,FA2H,SMPD2,ST3GAL1,UGCG,SGMS1,CLN8,CERS6,B4GALT4,ST6GALNAC3,CERS2 |
| 3.225e-03 | -5.74 | WLS (Wnt ligand secretion mediator) | protein interactions | 79971 | 85 | 36 | 19454 | 5460 |
TMUB1,KRAS,OPRK1,VIPR1,RAB5A,RAB9A,WNT7A,WNT2,RPN1,RAB4A,FAF2,NCSTN,SEC62,ERLIN2,GPR37,DUOXA2,CCR2,MARCHF4,ARF6,RNF128,SEC61B,RPRM,LMBR1L,RAB35,HRAS,CD63,STYK1,LAMTOR1,RHOB,CGRRF1,LAMP3,MOV10,RAB2A,CSK,RAB5C,OPRM1 |
| 3.231e-03 | -5.74 | endoplasmic reticulum organization | biological process | GO:0007029 | 98 | 42 | 18204 | 5365 |
TMCC1,CAMLG,JAGN1,EMC2,EMC4,ATL1,VAPB,TMEM170A,REEP3,CAV2,TRAM1L1,EMC9,EMC8,RETREG3,VCPIP1,RETREG1,TOR1B,TMEM147,TOR1AIP2,SPTSSB,ZBED3,RETREG2,REEP4,ESYT1,SGTA,STX18,REEP6,EMC10,EMC1,LPCAT3,RTN4,TMEM38B,RAB18,WDR83OS,TRAM1,LMAN1,CCDC47,TMEM33,SEC61A1,UBL4A,EMC6,TRAM2 |
| 3.234e-03 | -5.73 | ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)) | protein interactions | 10257 | 54 | 25 | 19454 | 5460 |
SLC4A8,CRELD1,CTXN1,RPA2,NHERF1,CFTR,LPAR1,TMEM268,LRTM2,RPA3,HAX1,H1-1,SNTA1,SAYSD1,LGALS8,KDSR,OPRL1,ESR2,VIRMA,CX3CL1,HNRNPL,LGALS3,MPP1,S1PR4,CD63 |
| 3.234e-03 | -5.73 | CORO7 (coronin 7) | protein interactions | 79585 | 54 | 25 | 19454 | 5460 |
DNAJC19,UBE2H,MYC,SAV1,RAB11A,DAG1,ELOC,MRPL50,ACTB,STK3,SRC,LMBR1L,AP2M1,AZIN2,ATG16L1,TP53,JUN,CDC42,DUSP22,WASL,AP1M1,RIGI,PML,SETD4,THBS3 |
| 3.234e-03 | -5.73 | IREB2 (iron responsive element binding protein 2) | protein interactions | 3658 | 54 | 25 | 19454 | 5460 |
ELAVL2,CIAO1,MDM2,KCTD10,PAIP1,ALYREF,ZNF174,STUB1,CCNF,LEMD3,BORCS8,ARL15,NHERF1,TFRC,APOBEC3D,SHMT1,PABPC5,H1-5,TOP3B,RAF1,RBCK1,KRAS,PSMA3,TERT,SRSF7 |
| 3.236e-03 | -5.73 | rRNA processing | biological process | GO:0006364 | 214 | 82 | 18204 | 5365 |
WDR12,POP5,DKC1,NOP9,PELP1,GTF2H5,POP7,RNASEL,RPS17,RPS14,EIF4A3,UTP6,TRMT112,RPF1,NOP58,RPL35,MRM2,WDR55,MAK16,EMG1,ZNHIT3,NPM3,NOC4L,RCL1,NOP53,RRP7A,RPL35A,UTP25,NOL7,EXOSC8,RPS7,METTL15,IMP3,PWP2,ZNHIT6,ISG20,RPS15,BRIX1,RPL26,BUD23,MRTO4,RPF2,LSM6,NHP2,LYAR,NOB1,FTSJ3,PPAN,TSR2,FCF1,PIH1D1,MPHOSPH10,WDR3,EXOSC1,RPL7A,SRFBP1,DROSHA,EXOSC3,METTL25B,TFB1M,MPHOSPH6,EXOSC4,TSR3,RPL7,KRR1,RIOK2,RPL27,C1D,NSA2,UTP15,RPS16,SUV39H1,NGDN,WBP11,RPL7L1,YBEY,RPS24,IMP4,UTP23,RPP25,RBM34,RPS28 |
| 3.254e-03 | -5.73 | PROTEASOME | prints domains | PR00141 | 7 | 6 | 5227 | 1528 |
PSMB6,PSMB5,PSMB9,PSMB7,PSMB11,PSMB10 |
| 3.259e-03 | -5.73 | skin-mucosal-malignant_melanoma-mucosal_lentiginous | COSMIC cancer mutations | skin-mucosal-malignant_melanoma-mucosal_lentiginous | 9 | 7 | 16828 | 4835 |
KRAS,HRAS,KIT,GNA11,TP53,GNAQ,PIK3CA |
| 3.259e-03 | -5.73 | mucosal_lentiginous | COSMIC cancer mutations | mucosal_lentiginous | 9 | 7 | 16828 | 4835 |
KRAS,KIT,HRAS,GNA11,TP53,GNAQ,PIK3CA |
| 3.259e-03 | -5.73 | haematopoietic_and_lymphoid_tissue-sinonasal_and_nasal_cavity-lymphoid_neoplasm-NK-T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-sinonasal_and_nasal_cavity-lymphoid_neoplasm-NK-T_cell_lymphoma | 9 | 7 | 16828 | 4835 |
TP53,KRAS,CTNNB1,KIT,EZH2,IDH2,IDH1 |
| 3.261e-03 | -5.73 | VEGFA-VEGFR2 Pathway | REACTOME pathways | R-HSA-4420097 | 330 | 127 | 10285 | 3229 |
IL3,ITGAV,RPS27A,SPRED1,PSMD4,PHB1,PSMC3,CTNNB1,CAV1,PSMA1,SEM1,DUSP1,VEGFA,RASGRP3,SHC1,PAK2,PSMB4,CTNNA1,PSMB2,PSMD1,NCKAP1,AKT3,PEA15,PSMA6,AKT1,HSP90AA1,PIK3CA,HSPB1,HRAS,PPP2CB,KIT,LAMTOR2,IL5,CYFIP2,VWF,PSMC1,CUL3,FGF16,IL2RB,CAMK2G,LAMTOR3,UBA52,FGF22,WDR83,RAF1,RAP1B,MAP2K1,KRAS,ROCK1,FGF10,PSMD10,FRS3,SRC,ROCK2,DUSP9,SPTAN1,PPP2R5E,PSMB3,PEBP1,MET,PAQR3,FGF23,PSMA5,CDC42,YWHAB,DUSP6,PPP2R5A,FGF1,IL2RG,PIK3R2,JUP,NEFL,DUSP10,MAP3K11,PSMB9,SPRED2,IL2RA,FGF3,PSME2,PSMD6,HBEGF,SHC3,RAP1A,AKT2,FGF7,JAK1,PSMD12,PRKCB,MAPKAPK3,CSF2,PRKACB,PRKCA,UBB,PPP2R1A,PSMD14,NCK1,PSMD7,FGF17,ELMO2,SPTBN1,PPP5C,ELMO1,WASF3,ANGPT1,PSME1,PSMB6,PSMA2,DLG4,BRAP,CSK,PSMA4,FGFR1,PSMC5,IL2,PSMB11,PSMB10,PSMB5,PSMA3,VAV2,PSMC4,PSMD3,JAK2,PSMB7,CTNND1,PIK3R1,PSMB1,AHCYL1 |
| 3.268e-03 | -5.72 | Interferon_reg_factor-3 | interpro domains | IPR019471 | 7 | 6 | 18521 | 5414 |
IRF9,IRF8,IRF4,IRF6,IRF7,IRF3 |
| 3.268e-03 | -5.72 | Glutaredoxin | interpro domains | IPR002109 | 7 | 6 | 18521 | 5414 |
GLRX2,GRXCR1,GLRX,TXNRD1,TXNRD3,GLRX5 |
| 3.268e-03 | -5.72 | Pept_T1A_subB | interpro domains | IPR000243 | 7 | 6 | 18521 | 5414 |
PSMB7,PSMB11,PSMB5,PSMB10,PSMB9,PSMB6 |
| 3.276e-03 | -5.72 | GPROTEING | prints domains | PR00321 | 13 | 9 | 5227 | 1528 |
GNG2,GNG13,GNG12,GNG11,GNG5,GNG10,GNG3,GNG7,GNGT2 |
| 3.276e-03 | -5.72 | ADSPHPHTASE | prints domains | PR01908 | 13 | 9 | 5227 | 1528 |
DUSP14,DUSP19,DUSP26,DUSP22,DUSP21,DUSP10,DUSP1,DUSP3,DUSP18 |
| 3.281e-03 | -5.72 | BRD2 (bromodomain containing 2) | protein interactions | 6046 | 415 | 142 | 19454 | 5460 |
RFC4,COIL,SAP18,ACTL6A,USP39,EIF3K,ELK3,FAU,GTF2F2,SNRPD2,MMP21,TAGLN2,APEX1,POLR2B,CBX5,GPBAR1,MYC,SMARCE1,RFC5,WDR20,H1-10,CHTOP,RPS26,TOP2B,RPL31,TYW5,BAG2,BLOC1S2,RUVBL2,CDK5,HMGN4,ASF1A,ZNF592,RFC3,SSRP1,POLDIP3,RFC2,DHX38,GPT,TOP3B,ZNF263,TNPO2,CAAP1,NFKBIL1,EZH2,SKA3,TAF10,DCUN1D5,SNRPE,SMARCB1,RBPJ,HP1BP3,BRD9,LYAR,SNX18,ZNF740,SRSF10,INO80E,BAZ1B,TAF7,BCL7C,DDX23,BCL2L1,RSBN1L,PRPF4,BANF1,NOG,DLAT,CCDC106,PPIH,ELOF1,FBXW7,UTP23,MBD3,GTF2H4,SAP30BP,MED30,DENND2D,HBB,METTL14,DCTN4,MACROH2A2,ACACA,EPHX1,EZH1,ZNF330,LIG3,TRIM24,MACROH2A1,CSNK2B,QSER1,DEK,CYP4F12,SH3BGRL,ZNF687,MED22,CAP2,SMARCA5,DNAJC8,AR,MTPN,PIP4K2C,PKNOX1,TADA3,SPOP,SNIP1,TFPT,RING1,ABCE1,VRK1,CAMKV,H3C1,MDC1,MEPCE,TP53,MTA3,H2AX,ADAMTS1,CBX3,DMAP1,NUPR1,TAF2,H2AZ1,RB1,TOP1,NKAP,CDC5L,AKAP17A,KMT5B,DKC1,COX5A,ERCC3,CSNK2A1,SMCHD1,MED29,NOS1AP,H2AC4,TOPBP1,BRD3,TAF9,NOL12,DNAJC7 |
| 3.288e-03 | -5.72 | negative regulation of neuron apoptotic process | biological process | GO:0043524 | 164 | 65 | 18204 | 5365 |
GCLC,CLU,NDNF,CNTFR,TGFB3,ANGPT1,IL6ST,MAP3K12,NONO,ATF4,HRAS,KRAS,PIK3CA,UCP2,CX3CL1,GBE1,PPT1,DLX1,IL10,BOK,NTF4,ROCK1,CTNNB1,STAMBP,SNCB,SLC1A1,BAX,CX3CR1,MT3,SOD2,CD2AP,NEFL,HTRA2,BTG2,GPRASP3,DNAJC5,CCND1,SLC25A27,NTRK2,VPS54,RETREG1,SOD1,PSEN1,NPPC,NR4A2,CLN8,BCL2L1,RAD21,FBXO7,STXBP1,JAK2,CCL2,MIR181C,VSTM2L,NRP1,MECP2,MIR195,UCN,AGAP2,PYCR1,TERT,PTPRZ1,MEF2C,ADNP,CITED1 |
| 3.293e-03 | -5.72 | cellular response to amyloid-beta | biological process | GO:1904646 | 44 | 22 | 18204 | 5365 |
AGER,MIR140,ADRB2,PSEN1,MIR146A,TLR4,MIR98,ATP1A3,BACE1,TLR6,FCGR2B,CDK5,GJA1,CASP4,CD36,IGF1R,ICAM1,EPHA4,MIR200A,MIR106B,IGF1,TNF |
| 3.293e-03 | -5.72 | positive regulation of epithelial cell apoptotic process | biological process | GO:1904037 | 44 | 22 | 18204 | 5365 |
CCL2,JAK2,MIR675,MIR125A,STK4,MIR101-1,MIR24-1,EIF2S1,BAX,PDCD4,IL6,CD248,MIR15A,SAV1,MIR132,CD40,TIA1,RGCC,MIR375,FASLG,CD40LG,SFRP4 |
| 3.293e-03 | -5.72 | membrane fission | biological process | GO:0090148 | 44 | 22 | 18204 | 5365 |
DNM2,CORO1C,CHMP5,SLC25A46,VPS28,EXOC3,EXOC1,CHMP1B,EXOC8,CHMP4C,EXOC5,VPS4B,TSG101,UBAP1,CHMP2A,SH3GLB1,EXOC2,HGS,CHMP2B,TMCC1,CHMP1A,VPS4A |
| 3.295e-03 | -5.72 | TPM2 (tropomyosin 2) | protein interactions | 7169 | 187 | 70 | 19454 | 5460 |
TMPO,CDK9,HAS3,COX4I1,ADD1,DSTN,CIART,CALR,HDAC6,HSPB8,TPM3,TNF,G3BP1,H1-6,TRIM37,CCAR1,RIGI,AHCYL1,GOLGA7,AKT2,TFPT,POC1B,PIK3CG,MRFAP1,TFCP2,TNNI1,DISC1,CAPZA2,RBPJ,CDK5R1,B3GNT2,ATP5PB,RAF1,ZNF704,CFAP97D1,ISG15,ACTN4,SNAPIN,PSMB9,JUN,TMEM205,ACTB,PSMB6,DYRK1A,VIRMA,UQCRC2,ZNF22,SRXN1,SP1,VMP1,ZNF250,MYC,NDUFB10,AKT1,SUB1,SCG3,NONO,ATAD1,HMGB1,FBXW7,DDX46,RPA3,SQSTM1,PCGF2,RPA2,MYL6,HECTD1,PKIG,PPP1CB,CFTR |
| 3.301e-03 | -5.71 | positive regulation of protein kinase activity | biological process | GO:0045860 | 256 | 96 | 18204 | 5365 |
LEP,DLG4,TLR4,PIK3CG,HSP90AA1,MAP3K12,PHB2,PRNP,ANGPT1,TPD52L1,GHR,SRC,PTPN1,MIR26B,PSRC1,FGFR1,DUSP19,CD86,PPIA,TOM1L1,FERMT2,ERP29,CACUL1,IFNG,IL12B,TAB2,TCIM,EPHA4,TLR3,DIPK2A,CCL5,CCNY,CAMK1,MIR21,CD4,LCP2,NTRK3,RGCC,IL4,EMP2,EZH2,PRKAG1,AGAP2,HSP90AB1,IL23A,IL34,TAB1,ADRB2,HRAS,PROX1,STK11,TLR6,CCR7,CAB39,FBXW7,CD40,IL1B,TNFSF15,RALB,AKT1,RPS3,CCND3,PHB1,MT3,TRAF2,RAP1A,TXN,GH1,MAP2K3,TGFB2,PDCD10,ADIPOQ,TNF,MAP3K11,IGF1,DLG3,XRCC5,DIRAS2,CARTPT,TGFBR2,DIRAS1,CCL19,CCND1,KIT,TRAF6,STRADB,FCGR1A,PIH1D1,MAP2K1,DVL2,CDKN1A,FGF1,MMD,CHI3L1,JAK2,PSMD10 |
| 3.302e-03 | -5.71 | Gprotein-gamma | interpro domains | IPR001770 | 13 | 9 | 18521 | 5414 |
GNGT2,GNG2,GNG11,GNG5,GNG10,GNG7,GNG13,GNG3,GNG12 |
| 3.305e-03 | -5.71 | rRNA metabolic process | biological process | GO:0016072 | 247 | 93 | 18204 | 5365 |
LSM6,LYAR,NOB1,FCF1,MPHOSPH10,EXOSC1,RPL7A,DROSHA,EXOSC3,GTF3C4,MPHOSPH6,KRR1,UTP15,SUV39H1,NGDN,WBP11,YBEY,RPS24,RPP25,RBM34,POP5,WDR12,PELP1,NOP9,TP53,RPS17,RNASEL,RPS14,UTP6,MARS1,NOP58,RPL35,WDR55,EMG1,ZNHIT3,RCL1,RRP7A,UTP25,RPL35A,POLR1B,TCOF1,PWP2,IMP3,RPS15,BUD23,RPF2,MRTO4,NHP2,PELO,FTSJ3,TSR2,PPAN,PIH1D1,WDR3,SRFBP1,POLR1D,METTL25B,TFB1M,TSR3,EXOSC4,RPL7,RIOK2,DIS3L,NSA2,C1D,RPL27,RPS16,GTF3C3,RPL7L1,IMP4,UTP23,TRIR,RPS28,DKC1,SIRT7,GTF2H5,POP7,EIF4A3,RPF1,TRMT112,MRM2,MAK16,NPM3,NOC4L,NOP53,EXOSC8,RPS7,NOL7,METTL15,ISG20,ZNHIT6,BRIX1,RPL26 |
| 3.311e-03 | -5.71 | clathrin-coated vesicle | cellular component | GO:0030136 | 220 | 83 | 19108 | 5553 |
ATP6V0B,VAMP2,ATP6V1G2,SPG21,SNAP91,CD3G,TFRC,RAB35,MYO6,RNASEK,RAB13,AP1M1,AP2A1,TF,SNX18,SFTPA1,CLBA1,SGIP1,FURIN,ATP6V1D,ATP6AP2,SYT2,FCHO2,CLRN1,SLC2A8,SNX3,AP1G2,AP2S1,GAD2,STX6,SFTPC,RAB3A,VPS33A,NECAP1,VWF,FCGR1A,SH3BP4,HSPA8,ADRB2,NECAP2,RAB5A,SCYL2,PHETA2,SFTPD,AP2M1,DNAJC5,SYNRG,PICALM,ATP6V1A,FOLR1,ASTN1,CD9,TMED9,LDLR,MLC1,AP1S2,VPS18,RGS19,RAB14,LMBRD1,FZD4,SLC32A1,CLVS2,VPS16,CTLA4,RAB8B,RAB27A,HAX1,AFTPH,DNM2,VAMP3,VAMP8,HBEGF,CLVS1,REEP6,TBC1D5,VAMP7,OCRL,DVL2,NCALD,CD4,ATP6V1C1,CFTR |
| 3.311e-03 | -5.71 | TMEM128 (transmembrane protein 128) | protein interactions | 85013 | 88 | 37 | 19454 | 5460 |
BCS1L,TMEM106A,LMNA,CD40,CXCR4,JAGN1,TMX2,PLSCR1,GAD2,RTN4,RABAC1,MRPS18B,SLC7A14,SCN3B,TMEM208,SLC1A3,CYB561,CD226,KCNJ10,REEP6,STX1A,ZDHHC15,SSMEM1,ELOVL4,CLN8,LHFPL2,MFSD5,RETREG3,CYBC1,GJA1,HSD17B11,REEP4,CD47,ARL6IP5,TMEM237,TMEM45B,FUNDC2 |
| 3.311e-03 | -5.71 | CISD3 (CDGSH iron sulfur domain 3) | protein interactions | 284106 | 88 | 37 | 19454 | 5460 |
CHCHD4,GSTK1,STOML2,COX5A,PMPCA,CLPX,MYC,GRSF1,SLC25A1,ESR2,ATP5PD,IDE,HNRNPL,UQCRC2,NDUFA5,NDUFS3,MMADHC,COX6C,ATP5PO,GLRX5,NDUFA2,ATP5PB,POLDIP2,ABHD10,MRPL22,MRPS33,CHCHD2,NDUFS2,MAVS,IGF1R,DLAT,NDUFC2,ATP5F1E,CLPB,SLC16A1,ATP5PF,S100B |
| 3.311e-03 | -5.71 | RNF114 (ring finger protein 114) | protein interactions | 55905 | 88 | 37 | 19454 | 5460 |
TRIM52,HNRNPDL,RIGI,HSPA5,CPLX1,UBE2K,UBE2D3,EWSR1,NUP50,SQSTM1,MAVS,LTBR,PML,PARP11,CDKN1A,UBE2W,RPSA,UBE2L3,SMURF1,ACP2,AK5,DYNLL1,DSTN,LHFPL4,PLP1,HSP90AA1,HSPB1,UBE2H,UBE2D1,UBE2E3,TRAF6,LACRT,TNFAIP3,UBE2E2,CUL3,XAF1,PLPP4 |
| 3.315e-03 | -5.71 | PTOV1 (PTOV1 extended AT-hook containing adaptor protein) | protein interactions | 53635 | 68 | 30 | 19454 | 5460 |
TOM1,HUWE1,FLOT1,CCR4,FTL,PTGES3,RTCB,MRFAP1,HAPSTR1,MTA2,RBPJ,SPTAN1,USP16,DYRK1A,APEX1,EGLN3,TMCC2,FEZ1,CCNF,YWHAZ,BECN1,MED10,YWHAB,SFN,CUL2,MYC,CREBBP,HDAC6,YWHAH,YWHAG |
| 3.315e-03 | -5.71 | SMYD3 (SET and MYND domain containing 3) | protein interactions | 64754 | 68 | 30 | 19454 | 5460 |
CSTF2T,CFTR,NDUFAB1,NFYB,TP53,MRPL47,MEST,NME1,CYP39A1,EZH2,RNF113A,MAGED4B,RPL27,PTGES3,MRPL41,CSE1L,SHC3,RPL7A,HSP90AA1,RPLP2,EED,TUBA1B,EEF1AKMT3,TMA7,MRPL24,HSP90AB1,NTMT1,RPS27L,MRPL23,HNRNPL |
| 3.315e-03 | -5.71 | TMEM106C (transmembrane protein 106C) | protein interactions | 79022 | 68 | 30 | 19454 | 5460 |
VAMP5,TMEM11,FAXDC2,STYK1,PLN,RPRM,PLP1,NRSN1,CXCL9,AIG1,TMEM97,DUOXA2,GOSR2,EDDM3B,TOR3A,CTXN3,TMEM106A,SEC22A,SFTPC,SSR1,GP9,RPN1,CHRNB2,CMTM7,TMEM106B,JAGN1,PGA4,HACD1,CD1B,PLPP6 |
| 3.327e-03 | -5.71 | Pink/Parkin Mediated Mitophagy | REACTOME pathways | R-HSA-5205685 | 23 | 14 | 10285 | 3229 |
UBA52,MAP1LC3B,TOMM22,RPS27A,UBB,SQSTM1,TOMM70,TOMM20,VDAC1,TOMM7,TOMM40,MAP1LC3A,MFN1,TOMM6 |
| 3.327e-03 | -5.71 | Mitophagy | REACTOME pathways | R-HSA-5205647 | 23 | 14 | 10285 | 3229 |
TOMM20,TOMM70,VDAC1,TOMM7,UBA52,TOMM22,MAP1LC3B,RPS27A,UBB,SQSTM1,TOMM40,MAP1LC3A,MFN1,TOMM6 |
| 3.334e-03 | -5.70 | NME4 (NME/NM23 nucleoside diphosphate kinase 4) | protein interactions | 4833 | 184 | 69 | 19454 | 5460 |
POLDIP2,LSM8,CRYZ,NME4,HSCB,ATP5F1E,GFM1,NGRN,ATPAF2,EXD2,MTRES1,LMO4,APEX1,ESR2,PARL,DKK3,TACO1,CCDC90B,ARMC7,DNAJC19,UBE2H,TUFM,MTG2,AUH,CDKN2D,PMPCA,FASTKD5,IMMP2L,ABHD10,ZBTB16,TNFSF8,CHCHD2,HINT2,COX8A,HSPD1,GFM2,ITGB8,PDHA1,NME1,GLRX5,AURKAIP1,SOCS3,SPG21,METTL15,FBP1,UBL5,RAF1,MRPL11,TP53,CIB3,FZR1,PRNP,YBEY,PSMB1,GATD3,CD274,SSBP1,MRPS26,RHOG,NME2,SNRNP70,TMEM70,DDRGK1,ACP6,CIDEB,MTRF1,GRSF1,MOV10,PFDN5 |
| 3.347e-03 | -5.70 | Glutaredoxin | pfam domains | PF00462 | 7 | 6 | 17795 | 5224 |
GRXCR1,GLRX2,GLRX5,TXNRD1,TXNRD3,GLRX |
| 3.347e-03 | -5.70 | IRF-3 | pfam domains | PF10401 | 7 | 6 | 17795 | 5224 |
IRF8,IRF3,IRF4,IRF9,IRF6,IRF7 |
| 3.350e-03 | -5.70 | T cell proliferation | biological process | GO:0042098 | 76 | 34 | 18204 | 5365 |
PRKCQ,FOXP3,ALKBH5,NDFIP1,LILRB1,GJA1,SASH3,PSMB10,PRDX2,IL20RB,PELI1,PIK3CG,TNFSF18,MSN,DLG1,LIPA,EFNB1,IL2,IDO1,IL12B,TP53,RC3H2,IL2RA,LMBR1L,CD151,IL15,CCND3,SELENOK,IL23A,GPAM,BAX,FKBP1B,NCSTN,CD28 |
| 3.355e-03 | -5.70 | regulation of protein localization to cell periphery | biological process | GO:1904375 | 138 | 56 | 18204 | 5365 |
CPLX1,NGDN,PPP2R5A,RHOG,PID1,PIK3R1,PIK3R2,AR,PICALM,ATP2C1,TMEM59,DLG1,ARF6,PIAS1,NETO2,STX7,LGALS3,BCL2L1,ATP2B4,RER1,VTI1B,AP2M1,LYPLA1,RAMP3,CNPY4,PRKCE,AKT1,DAG1,VAMP8,STAC3,EPHA2,CDK5,KCNJ11,ZDHHC8,RANGRF,TMBIM1,HRAS,LZTFL1,SQSTM1,GPC4,PRNP,CLIP3,AGR2,STX8,MMP14,DPP10,IFNG,SPTBN1,ACTB,TNF,MIR223,PGRMC1,VPS4A,EFCAB7,CSK,RAP1A |
| 3.355e-03 | -5.70 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | molecular function | GO:0016616 | 122 | 51 | 18094 | 5411 |
HSD17B1,HSD17B11,HSD17B10,EHHADH,RDH11,HADHA,LDHA,AKR1C1,SPR,RDH10,NSDHL,IDH2,IDH3B,LDHB,SORD,DHRS4,MDH1,SDR42E1,DHRS4L1,HSD11B1,DHRS7,CRYL1,UGDH,AKR1A1,G6PD,CBR4,AKR7A2,DHRS7B,IDH3A,CBR3,KDSR,HSD17B8,DHRS1,IDH1,AKR1C2,SDR16C5,CTBP1,GFUS,AKR1B1,CYP27A1,HADH,LDHAL6B,HSD17B6,DHRS11,DHRS3,ADH1A,HSD17B3,ADH1B,RDH12,AKR1E2,KCNAB1 |
| 3.356e-03 | -5.70 | early endosome | cellular component | GO:0005769 | 436 | 153 | 19108 | 5553 |
ZMPSTE24,TMEM30A,CD274,AP1AR,PLD3,STX8,VPS18,PICK1,B2M,AP1S2,LDLR,TOM1,PLEKHJ1,TLR4,HPS6,SLC1A1,TICAM1,VPS16,CLVS2,LDLRAD4,SIAH2,VAMP3,KCNH1,HFE,HSD17B6,EHD3,CMTM6,TICAM2,RAB31,TSG101,TLR3,FLOT1,TRAK2,PTPN1,OR51E2,PLEKHF2,SNX5,ARF6,CD4,TFRC,STAMBP,FCMR,RAB22A,ARRDC3,NTRK2,EPHA4,NF2,RAB5C,BOK,FIG4,VTI1B,TBC1D16,CHMP1A,PML,VPS4A,DERL1,USP8,RAB1A,BACE1,VAC14,APH1A,MYO1B,VIPAS39,LAMP3,STX12,AP3S2,FCGR1A,HAS3,PCSK9,PSEN2,PLA2G4B,RAB29,RAP1A,RND2,LAMP5,SLC11A2,PICALM,STX7,VPS28,SYNDIG1,NIPA2,MLC1,MARCHF3,PSEN1,DKK1,RHOB,LITAF,RAB14,SERPINB1,APOC2,NRP1,PHB1,TMEM127,MAP2K1,VPS26A,TOLLIP,TM9SF4,PLEKHF1,CLVS1,TMEM108,VAMP8,CAV1,PTP4A2,PARM1,OCRL,REP15,SLC31A1,SNX2,NSG1,CD1E,CFTR,UBXN6,ACKR3,MME,EHD4,CXCR4,LRP6,TF,AP1M1,PRDX3,AKT2,VPS26B,SNX1,SNX17,SNX12,DERL2,TRIM3,EHD1,SNX3,NME1,RNF11,RAB4A,GRIA1,GPNMB,INPP4A,CLIP3,FGD2,HSPD1,TRIM27,VPS33A,RAB32,ABCB9,STX6,MTMR2,ADRB2,NCSTN,ADRB1,HGS,PTP4A3,PDLIM4,SNX20,PHETA2,RAB5A |
| 3.389e-03 | -5.69 | NEIL3 (nei like DNA glycosylase 3) | protein interactions | 55247 | 91 | 38 | 19454 | 5460 |
MAP4,CDKN2AIP,RSBN1L,HSP90AA1,HBA1,SLC2A1,CIRBP,BCL7C,ENY2,PRRC2A,HSP90AB1,ROCK1,SNRPA1,PRNP,PRKRA,EIF2AK2,TNFRSF1B,PSPC1,ACACA,NEFL,TP53,UBA52,STRBP,FTL,PTGES3,HNRNPDL,STAU1,RUVBL1,HNRNPA0,SLC31A1,HNRNPF,DHX9,HMCES,EWSR1,RUVBL2,XRCC5,HNRNPA2B1,MAP1B |
| 3.389e-03 | -5.69 | SPART (spartin) | protein interactions | 23111 | 91 | 38 | 19454 | 5460 |
OTUD7B,COPS5,WWP2,CUL3,DESI2,LAMTOR1,LMNB1,ACSL4,AIFM1,CCNF,PHB1,SMURF1,VIRMA,USP5,CETN2,HYPK,MAP1LC3B,DNAJC25,TUBA1A,TBK1,DPH5,KLC2,OTULIN,RAD23B,RPA2,WWP1,GPR35,AKAP1,EP300,HADHA,SQSTM1,ZYX,HSPD1,RPA3,BAP1,PML,HSPA5,STAU1 |
| 3.389e-03 | -5.69 | TRAPPC12 (trafficking protein particle complex subunit 12) | protein interactions | 51112 | 91 | 38 | 19454 | 5460 |
CMBL,TRAPPC3,TRAPPC10,ARF1,TRAPPC6B,POLE3,HSP90AB1,RAB1B,CAND1,PRDX2,PRNP,FBXO7,SLC30A5,RAB2A,ATG9A,LIN7B,RAB5C,TRAPPC4,IGF2BP1,HNRNPD,TRAPPC2L,IGF1R,BET1L,MTDH,SLC39A9,RAB1A,TRAPPC1,HNRNPA2B1,ARL5B,B3GNT2,PTAR1,TOP3B,FUT8,TRAPPC13,TRAPPC3L,TRAPPC6A,CTBP1,TFCP2 |
| 3.389e-03 | -5.69 | IDH3B (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta) | protein interactions | 3420 | 91 | 38 | 19454 | 5460 |
HSPD1,RPA3,IDH3A,IDH1,EP300,GFM1,COX8A,HSCB,FBXW7,ADRB2,NT5C3A,RIGI,TP53,CARTPT,CFTR,RPA2,EZH2,IDH2,PDHA1,PIH1D1,CSNK1A1,IRF2,CD274,CCNF,RAB35,FBXO32,GATD3,RPGRIP1L,DBT,EGLN3,CHI3L1,CDK9,MOV10,MYC,AUH,CTNNB1,RHOG,UBE2H |
| 3.389e-03 | -5.69 | POLD3 (DNA polymerase delta 3, accessory subunit) | protein interactions | 10714 | 91 | 38 | 19454 | 5460 |
PCNA,BAP1,RPA3,PRIM2,POLD2,PML,POLA2,SSRP1,KRAS,HSCB,H3C1,DCP2,USP8,TSHR,FAF2,KLRD1,TULP3,TP53,TAF2,CBX3,RPA2,SLC1A1,CCNF,DUOXA2,APLNR,POLE3,MAD2L2,RBBP4,TOP1,XPO1,MCM3,MYC,CUL3,AHSA1,POLD4,THTPA,RIT1,MED10 |
| 3.389e-03 | -5.69 | DHRS2 (dehydrogenase/reductase 2) | protein interactions | 10202 | 91 | 38 | 19454 | 5460 |
PPME1,HBB,NHERF1,SDC2,STMN2,CFTR,TRMT13,DET1,FBXL19,RAF1,ATG16L1,RIGI,STAU1,FBXW7,RBBP7,HADHA,APPBP2,TCEA2,DVL2,HIRA,PREPL,CLP1,CDC73,COP1,DCAF4,DDX23,ANAPC15,FBXO7,WWP2,MYC,ESR2,PHTF2,MDM2,CD4,MYBL2,SMU1,ELOVL4,SDC4 |
| 3.395e-03 | -5.69 | PABIR2 (PABIR family member 2) | protein interactions | 159090 | 38 | 19 | 19454 | 5460 |
NUP50,FHL3,BAP1,PPP2CB,TUSC3,APEX1,DYRK1A,PPP2R2C,SNRNP40,NTAQ1,YWHAH,PPP2R1A,XPO1,YWHAG,WDR83,SFN,KPNA1,YWHAB,YWHAZ |
| 3.395e-03 | -5.69 | GABBR1 (gamma-aminobutyric acid type B receptor subunit 1) | protein interactions | 2550 | 38 | 19 | 19454 | 5460 |
TPD52L1,CRELD1,GOLGA5,YWHAZ,USP14,ORMDL3,GNG2,KCTD16,ATF4,MAX,GNB1,GPR37,ZDHHC17,KCNJ3,ALB,DDIT3,GNAO1,JAKMIP1,PPP1R12A |
| 3.395e-03 | -5.69 | TNK1 (tyrosine kinase non receptor 1) | protein interactions | 8711 | 38 | 19 | 19454 | 5460 |
G6PD,MATR3,SPPL3,G3BP1,NDFIP1,HNRNPH2,DDX5,FAM168A,DDX1,HSP90AA1,YWHAB,YWHAZ,YWHAH,FAF2,YWHAG,HNRNPA1,ZNF250,SFN,GRB10 |
| 3.395e-03 | -5.69 | MITD1 (microtubule interacting and trafficking domain containing 1) | protein interactions | 129531 | 38 | 19 | 19454 | 5460 |
NUPR1,CHMP1A,ISG15,EEF1A1,SOX2,NTAQ1,TTC33,RAB5C,ATP6AP2,TFG,CHMP2A,CHMP1B,CHMP5,GPHN,ZNF655,MCPH1,RPRD1A,HRAS,XRCC5 |
| 3.401e-03 | -5.68 | MAPK3 (mitogen-activated protein kinase 3) | protein interactions | 5595 | 396 | 136 | 19454 | 5460 |
PPME1,RNF181,UBL4A,AKR1C1,COMMD8,TP53,MAP2K3,HADH,DUSP1,PPARA,KPNA2,VTA1,CTNND1,TAL2,TUBG1,NR4A2,STAR,H2AC4,GRSF1,MTMR12,COPS5,HDAC6,FCGR2B,DCUN1D1,PRNP,ZNF7,CAV1,SURF6,IER3,RB1,CDK1,RPA2,BTG2,PRKCA,HEXIM1,ATG16L1,WDR83,EDF1,SNRNP27,MAFG,GTF2I,FBXW7,HSPA5,BTBD10,SNCG,RPA3,PML,SPOP,ATP1A1,STK11,SMAD2,PEA15,NCKIPSD,PTPN11,DHPS,GMPS,STAT5A,DAPK1,TRIM54,PRKCE,FERMT2,SRC,DUSP3,DUSP10,STUB1,GAB1,CCNF,METAP2,ABHD14B,CSNK2B,STMN2,SCAND1,RAB4A,VDR,RAF1,TPD52,NUP153,SOX2,JUN,TULP3,CSTF2T,VDAC1,FKBP2,TOP2B,PLCB1,SLC25A23,PEDS1,CDC23,NAB2,IFI16,PTPN5,LRRC4,YWHAG,HSPB8,MAP3K14,TTC9C,DYNC1I2,TRIM15,ELK1,NTMT1,WIF1,HSP90AB1,CPXM1,DUSP6,FBXO32,GJA1,KRT8,PAK2,MAP2K1,ZBTB42,SYK,PRDX3,ELK4,HSCB,ITGAV,FOXP2,DUSP9,FOS,HSPA8,BRCA1,RPS6KA4,SP1,NTRK3,HSP90AA1,HTRA2,ILK,MYC,CREBBP,HMGCS1,GALE,ATP5F1B,LGALS3,LAMTOR3,APEX1,ESR2,ETNK2 |
| 3.407e-03 | -5.68 | PACS1 (phosphofurin acidic cluster sorting protein 1) | protein interactions | 55690 | 46 | 22 | 19454 | 5460 |
PPP2CB,FAAP100,ATG4A,KRAS,HNRNPL,SGF29,SNX24,ESR2,TP53,WDR37,YWHAG,CSNK2A1,YWHAH,JUN,LEAP2,DDX39A,PPP1CB,FGFR1,PPT1,GDI2,RHOG,FURIN |
| 3.407e-03 | -5.68 | EXOG (exo/endonuclease G) | protein interactions | 9941 | 46 | 22 | 19454 | 5460 |
ZCCHC10,BORCS6,DDX39A,APOO,SEC62,BZW2,CHCHD4,CDH8,LAMTOR1,ZER1,SFXN1,AIFM1,CXCR4,TMEM74,CLPB,SYT2,EIF2B5,EIF2B2,RANBP6,SLC25A12,PARL,MEPCE |
| 3.407e-03 | -5.68 | PNISR (PNN interacting serine and arginine rich protein) | protein interactions | 25957 | 46 | 22 | 19454 | 5460 |
SNRNP40,DYRK1A,CDC5L,SRPK2,ESR2,DDX23,UBE2H,HSPB1,EDEM1,MOV10,BAG3,XPO1,CAMKV,RPS24,EWSR1,CDK8,MED23,TP53,ATG16L1,CDK7,CD2BP2,CDC42 |
| 3.407e-03 | -5.68 | ABCC5 (ATP binding cassette subfamily C member 5) | protein interactions | 10057 | 46 | 22 | 19454 | 5460 |
RHOG,AK2,LAMTOR1,RHOB,TIAM1,H1-1,H1-5,MOV10,RAB2A,SCN3B,SERPINA3,CDC42,ARF6,KRAS,RHOJ,RHOH,PDE2A,CAV1,RHOU,RAB35,RAC2,RBP5 |
| 3.411e-03 | -5.68 | KIDINS220 (kinase D interacting substrate 220) | protein interactions | 57498 | 178 | 67 | 19454 | 5460 |
RAB5C,LAMP2,ATG9A,LAMP3,RHOG,STYK1,MYEF2,PTPN1,RAB35,RAC2,GJA1,RHOH,DNAJC1,HNRNPL,CAV1,DIRAS3,EGLN3,STX6,LGR4,FAF2,SOX2,RAB4A,PDHA1,CRKL,FURIN,RND3,TMT1A,ZYX,NTRK2,FHL3,LDLRAD4,KRAS,FLOT1,SAR1B,RAB11A,RAB2A,MYC,DNAJC5,TIA1,RHOB,CGRRF1,CD226,LAMTOR1,EPHA2,NTRK3,CDC73,CTNNA1,CD79B,LMBR1L,GSK3A,MOB4,TMEM74,TAX1BP1,RHOJ,MANSC1,VIRMA,B4GAT1,ATP6AP2,APLNR,BET1,RND2,CDC42,RHOU,RAB9A,STAU1,EMC1,STX7 |
| 3.422e-03 | -5.68 | central nervous system maturation | biological process | GO:0021626 | 7 | 6 | 18204 | 5365 |
ATP6AP2,CEND1,CDK5R1,RERE,ARCN1,CX3CR1 |
| 3.422e-03 | -5.68 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator | biological process | GO:1902255 | 7 | 6 | 18204 | 5365 |
RPL26,UBB,MIR186,MYC,MSX1,RPS7 |
| 3.422e-03 | -5.68 | regulation of vitamin D biosynthetic process | biological process | GO:0060556 | 7 | 6 | 18204 | 5365 |
IFNG,CYP27B1,GFI1,TNF,NFKB1,SNAI2 |
| 3.422e-03 | -5.68 | chaperone-mediated autophagy | biological process | GO:0061684 | 7 | 6 | 18204 | 5365 |
STUB1,HSPA8,LAMP2,HSP90AA1,BAG3,CLU |
| 3.422e-03 | -5.68 | glycosylceramide biosynthetic process | biological process | GO:0046476 | 7 | 6 | 18204 | 5365 |
FA2H,B4GALT3,UGCG,GAL3ST1,B3GALT1,B3GALT2 |
| 3.422e-03 | -5.68 | heat generation | biological process | GO:0031649 | 7 | 6 | 18204 | 5365 |
IL1B,ADRB1,ADRB2,ARRDC3,ADRB3,IL1A |
| 3.427e-03 | -5.68 | positive regulation of nitric oxide biosynthetic process | biological process | GO:0045429 | 39 | 20 | 18204 | 5365 |
SMAD3,AKT1,IL1B,IFNG,MIR99B,CLU,TICAM1,JAK2,TNF,DDAH1,SOD2,TLR4,KLF4,DDAH2,HSP90AA1,CD36,CLEC7A,TLR6,HBB,HSP90AB1 |
| 3.427e-03 | -5.68 | regulation of monooxygenase activity | biological process | GO:0032768 | 39 | 20 | 18204 | 5365 |
TNF,GFI1,NOSIP,ATP2B4,NOS1AP,IL1B,IFNG,CYP27B1,AKT1,IL1A,FGF23,NFKB1,VDR,TERT,MIR130B,CAV3,POR,LEP,MIR378A,NUS1 |
| 3.428e-03 | -5.68 | RYR3 (ryanodine receptor 3) | protein interactions | 6263 | 18 | 11 | 19454 | 5460 |
FBXO22,SRI,PTEN,RTN4,BCL2L1,FKBP1A,FKBP1B,METTL14,TIAM1,CFTR,DDX39A |
| 3.428e-03 | -5.68 | CYTB (cytochrome b) | protein interactions | 4519 | 18 | 11 | 19454 | 5460 |
KRAS,MRPL18,MRPL50,UQCRQ,UQCRH,CLDND1,CYC1,UQCRC2,KDSR,CCR6,BORCS6 |
| 3.428e-03 | -5.68 | ARL17A (ADP ribosylation factor like GTPase 17A) | protein interactions | 51326 | 18 | 11 | 19454 | 5460 |
SLC31A1,KRAS,CX3CL1,TSPAN3,FTL,KCNA2,MICB,TMEM74,DDX39A,GGT7,LHFPL2 |
| 3.428e-03 | -5.68 | Gm9174 (cell division cycle 26 pseudogene) | protein interactions | 668450 | 18 | 11 | 19454 | 5460 |
ANAPC2,NEK2,ANAPC16,ANAPC13,CDC26,CDC16,ANAPC4,CDC23,CDC20,MAD2L1,FZR1 |
| 3.428e-03 | -5.68 | FAM163A (family with sequence similarity 163 member A) | protein interactions | 148753 | 18 | 11 | 19454 | 5460 |
TRIM68,P3H1,CRTAP,YWHAZ,YWHAB,TMEM179B,SFN,YWHAG,YWHAH,KLHL22,GAD2 |
| 3.428e-03 | -5.68 | CYP17A1 (cytochrome P450 family 17 subfamily A member 1) | protein interactions | 1586 | 18 | 11 | 19454 | 5460 |
UBA52,CDO1,CYB5A,RPAIN,IGF1R,ATP5F1E,POR,FZR1,HSP90AB1,STK11,TIGD7 |
| 3.428e-03 | -5.68 | UCK1 (uridine-cytidine kinase 1) | protein interactions | 83549 | 18 | 11 | 19454 | 5460 |
PLA2G12A,UPRT,HSP90AA1,UCK1,UCK2,RPA2,NUBP2,PRMT5,PGK1,HNRNPK,SPPL3 |
| 3.428e-03 | -5.68 | SERINC3 (serine incorporator 3) | protein interactions | 10955 | 18 | 11 | 19454 | 5460 |
VDAC2,HACD3,SLC16A1,XPO5,KDELR2,SURF4,P2RY1,RPS15,KDELR1,PHB2,RIGI |
| 3.428e-03 | -5.68 | MCF2L (MCF.2 cell line derived transforming sequence like) | protein interactions | 23263 | 18 | 11 | 19454 | 5460 |
RABAC1,CDC42,TOP3B,VIRMA,YAE1,GNB1,APEX1,HSPE1,HSP90B1,RHOG,HNRNPL |
| 3.432e-03 | -5.67 | endoplasmic reticulum chaperone complex | cellular component | GO:0034663 | 11 | 8 | 19108 | 5553 |
PDIA6,UGT1A1,PPIB,HSP90B1,HSPA5,MZB1,SDF2L1,DNAJC10 |
| 3.432e-03 | -5.67 | RPAP3/R2TP/prefoldin-like complex | cellular component | GO:1990062 | 11 | 8 | 19108 | 5553 |
PFDN2,RPAP3,DNAAF10,PFDN6,RUVBL2,PDRG1,RUVBL1,PIH1D1 |
| 3.434e-03 | -5.67 | regulation of cell development | biological process | GO:0060284 | 839 | 283 | 18204 | 5365 |
SMARCB1,MECP2,SLITRK1,IKBKB,IL34,MYRF,BMPR1A,MIR181C,PRELID1,IL15,FBXO7,MIR137,PRMT6,LGALS3,EZH2,DROSHA,UBASH3B,NF2,LHX2,IL7,FBXO22,VEGFA,SEMA7A,B2M,TFE3,IL23A,YTHDF2,BMPR2,FAXDC2,AMIGO1,IRF1,F11R,NR2E1,TSPO,PIK3R1,BTG2,CTNNBIP1,FZD4,NIBAN2,NTRK2,UFL1,IFNG,TCIM,TP53,TIAM1,ACTL6B,PAFAH1B1,BRINP1,CLEC7A,MITF,HOXB8,TNFAIP6,ROCK1,TMEM176B,DAG1,HELT,PRDX2,IL18,CRABP2,NKAP,TLR4,RNF41,THY1,CDK6,FGL2,CCL11,DISC1,FOS,HCLS1,IL2RA,NPPC,ADNP,RB1,FGF13,ZNF365,RAG1,IL15RA,LDB1,MIR222,NLRP3,FXR2,TRAF6,TLR2,PRKCA,NEFL,CTLA4,RHOH,XRCC5,TRIB1,F2,CCR2,IRF4,EEIG1,CCL19,RNF10,PTHLH,WEE2,FERD3L,ROCK2,IL10,CERS2,CX3CL1,VSIR,TNF,ADIPOQ,ACTB,CD2,GPR171,CX3CR1,MIR145,TESPA1,NKX6-2,WNT2,TRIM32,CDK5,KLF10,ACVR1B,BCL6,CXCL12,MME,HMGB1,PITHD1,SYK,DUSP10,BATF,AGER,STK11,TRIM46,GABPA,HDAC6,CXCR4,S100A10,NOG,TESC,FCGR2B,TBC1D24,FBXW7,RC3H2,MEAF6,WNT10B,TRIM11,IFNB1,TYROBP,PAX6,CAV3,EFNA5,MEF2C,CD28,PTPRZ1,CD80,CBFB,IL4,NPTN,TCTA,GPRASP3,ZBTB16,SOCS5,SMURF1,RUNX1,RTN4,SMARCD3,TNFRSF1B,TLR9,PLCB1,LILRB4,EGR2,MIR146A,PSEN1,INHA,CDC73,PTN,IFNA2,CD4,MIR21,MIR30B,ANAPC2,SYT4,CD46,DLX1,MMP14,IL12B,SOS2,EPHA4,TLR3,MIR223,FOXP1,MIR142,ASPM,BGLAP,CD86,CREB1,ID4,SFRP1,HAPLN2,IL6,MYC,LILRB1,FOXP3,LDLR,CCL3,CD83,PLXNC1,PNP,PPP1R12A,YWHAH,SASH3,ACTL6A,FRZB,JUNB,GPR37L1,VEGFC,KLHL25,GPR137,OPRM1,SMARCE1,HEY2,IL6ST,BTN2A2,HAX1,ING5,KDM1A,NRP1,STAT1,IRF7,PTEN,IL5,BAD,TMEM176A,RGMA,GSK3A,MAP2K1,CCR1,PPP1CC,TOB2,L1CAM,LTA,NDFIP1,RHEB,KIT,FZD3,CTNNA1,TNR,XBP1,PAEP,RND2,CARTPT,SOD1,IFRD1,IL2,TGFBR2,MIR221,DICER1,SNAI2,CTDSP1,SKIC8,ASPA,IL1A,EP300,IGF1,NOTCH2,KRAS,NFKBIA,TOX,IL2RG,MT3,MAP1B,NPR2,ADD1,CTNNB1,IL1B,C1QC,SPP1,RFLNA,AKT1,PPP3CA,WNT7A,SMAD4,DRD3,PROX1,BHLHE40,ISG15,SEMA5A,PRMT5 |
| 3.436e-03 | -5.67 | anterograde trans-synaptic signaling | biological process | GO:0098916 | 415 | 148 | 18204 | 5365 |
SST,COMT,PDLIM4,GABBR1,EXT1,VDAC1,HTR1F,GRIK1,LARGE1,STAC3,CPLX3,HTR2A,ADORA1,SNAP29,GRM1,CHRM5,HOMER1,SNAP25,FGF12,DLG4,SLC1A3,PMP22,TAC1,NPBWR1,FCHSD2,SDCBP,PAFAH1B1,CACNB2,PPFIA3,HCRT,NLGN1,GLRA1,HTR5A,RIMS3,SLITRK5,CHRM4,SLC6A2,SNCB,MPZ,SYT2,CNP,GABRA1,PNOC,GABRB2,NQO1,SNCG,DNAJC5,CPLX1,CLSTN3,SYT4,LIN7C,GRIA2,CBLN2,SV2B,OPRK1,PSEN1,PCDHB13,GJC1,INSYN2A,TPBG,GABRA2,ACHE,MECP2,HTR1A,SNAPIN,SLC32A1,CHRNA7,SYN3,CHRNB2,EZH2,INSYN1,MEF2C,SLC6A1,NPY,WNT7A,PPP3CA,GABRB3,STX1A,CDK5,KCND2,AKT1,LIN7B,GABARAP,DRD3,CHRDL1,STX11,RIMS4,SLC6A3,PPT1,NSG1,HRH2,CACNB3,NPR2,GABRG2,RAP1A,ASIC1,DBH,SLC1A2,HRH3,CTNNB1,SLC1A1,CRHBP,KCNMB1,GHRL,UTS2,GRIA1,SCN2B,SNAP23,INSYN2B,GLRB,TNR,NLGN2,VPS54,NAPA,CBLN1,SLC29A1,GRM2,DLG3,DLG1,NPTX1,LYNX1,RAB3A,PDYN,CARTPT,RIC3,PTEN,STXBP1,USP14,CHRM1,VAMP2,SYPL1,TMOD2,RIT2,GAD2,GPR176,GLRA2,CHRM3,CPLX2,CACNB4,PRKCE,DRD1,KCNIP2,GSK3A,KCNJ8,ASIC2,NPY5R,PLP1,GRID1 |
| 3.436e-03 | -5.67 | chemical synaptic transmission | biological process | GO:0007268 | 415 | 148 | 18204 | 5365 |
SNCG,GABRB2,NQO1,CPLX1,DNAJC5,OPRK1,SV2B,LIN7C,CBLN2,GRIA2,SYT4,CLSTN3,INSYN2A,GJC1,PCDHB13,PSEN1,ACHE,GABRA2,TPBG,HTR1A,MECP2,SLC32A1,SNAPIN,MEF2C,INSYN1,EZH2,CHRNB2,CHRNA7,SYN3,EXT1,GABBR1,PDLIM4,COMT,SST,ADORA1,HTR2A,LARGE1,STAC3,CPLX3,GRIK1,HTR1F,VDAC1,HOMER1,CHRM5,GRM1,SNAP29,PMP22,SLC1A3,DLG4,FGF12,SNAP25,PPFIA3,CACNB2,SDCBP,PAFAH1B1,FCHSD2,NPBWR1,TAC1,RIMS3,HTR5A,GLRA1,HCRT,NLGN1,SNCB,SLC6A2,CHRM4,SLITRK5,PNOC,GABRA1,CNP,MPZ,SYT2,INSYN2B,SNAP23,SCN2B,GRIA1,GHRL,UTS2,NLGN2,TNR,GLRB,GRM2,SLC29A1,CBLN1,NAPA,VPS54,RIC3,CARTPT,PDYN,LYNX1,NPTX1,RAB3A,DLG1,DLG3,VAMP2,SYPL1,CHRM1,USP14,STXBP1,PTEN,GLRA2,GPR176,GAD2,TMOD2,RIT2,ASIC2,KCNJ8,KCNIP2,GSK3A,DRD1,CACNB4,PRKCE,CPLX2,CHRM3,GRID1,PLP1,NPY5R,GABRB3,PPP3CA,WNT7A,NPY,SLC6A1,AKT1,KCND2,CDK5,STX1A,GABARAP,LIN7B,STX11,CHRDL1,DRD3,SLC6A3,RIMS4,CACNB3,HRH2,PPT1,NSG1,SLC1A1,CRHBP,HRH3,CTNNB1,ASIC1,DBH,SLC1A2,RAP1A,NPR2,GABRG2,KCNMB1 |
| 3.445e-03 | -5.67 | human chr9p13.3 | chromosome location | human chr9p13.3 | 84 | 30 | 26134 | 5823 |
AQP3,CNTFR,ARHGEF39,NUDT2,TESK1,CREB3,CCL21,SIGMAR1,RUSC2,RPP25L,FANCG,CHMP5,SIT1,CCL27,ATOSB,RGP1,NPR2,MYORG,HINT2,DCTN3,STOML2,UBAP1,CCIN,GLIPR2,MIR4667,ENHO,CCL19,SPMIP6,FAM219A,MSMP |
| 3.450e-03 | -5.67 | lung-bronchus-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-bronchus-carcinoid-endocrine_tumour-typical | 20 | 12 | 16828 | 4835 |
TP53,CTNNB1,KRAS,MET,FBXW7,AKT1,PIK3CA,MAP2K1,FGFR1,STK11,SMAD4,PTEN |
| 3.450e-03 | -5.67 | lower_lobe | COSMIC cancer mutations | lower_lobe | 20 | 12 | 16828 | 4835 |
AKT1,FBXW7,CTNNB1,KRAS,MET,TP53,PTEN,SMAD4,FGFR1,STK11,PIK3CA,MAP2K1 |
| 3.450e-03 | -5.67 | lung-lower_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-lower_lobe-carcinoid-endocrine_tumour-typical | 20 | 12 | 16828 | 4835 |
CTNNB1,KRAS,MET,TP53,AKT1,FBXW7,FGFR1,STK11,PIK3CA,MAP2K1,PTEN,SMAD4 |
| 3.450e-03 | -5.67 | lung-bronchus-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-bronchus-carcinoid-endocrine_tumour-atypical | 20 | 12 | 16828 | 4835 |
STK11,FGFR1,MAP2K1,PIK3CA,PTEN,SMAD4,MET,KRAS,CTNNB1,TP53,AKT1,FBXW7 |
| 3.450e-03 | -5.67 | lung-middle_lobe-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-middle_lobe-carcinoid-endocrine_tumour-atypical | 20 | 12 | 16828 | 4835 |
TP53,MET,CTNNB1,FBXW7,AKT1,PIK3CA,FGFR1,PTEN,KRAS,MAP2K1,STK11,SMAD4 |
| 3.450e-03 | -5.67 | lung-upper_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-upper_lobe-carcinoid-endocrine_tumour-typical | 20 | 12 | 16828 | 4835 |
TP53,CTNNB1,KRAS,MET,FBXW7,AKT1,PIK3CA,MAP2K1,FGFR1,STK11,SMAD4,PTEN |
| 3.450e-03 | -5.67 | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | 20 | 12 | 16828 | 4835 |
PTEN,TERT,PIK3CA,FBXW7,KIT,RB1,CTNNB1,TP53,EWSR1,IDH1,HRAS,KRAS |
| 3.450e-03 | -5.67 | lung-middle_lobe-carcinoid-endocrine_tumour-typical | COSMIC cancer mutations | lung-middle_lobe-carcinoid-endocrine_tumour-typical | 20 | 12 | 16828 | 4835 |
KRAS,SMAD4,STK11,MAP2K1,AKT1,FBXW7,MET,CTNNB1,TP53,PTEN,FGFR1,PIK3CA |
| 3.450e-03 | -5.67 | myxofibrosarcoma | COSMIC cancer mutations | myxofibrosarcoma | 20 | 12 | 16828 | 4835 |
PTEN,TERT,PIK3CA,FBXW7,RB1,KIT,CTNNB1,TP53,EWSR1,IDH1,HRAS,KRAS |
| 3.450e-03 | -5.67 | upper_lobe | COSMIC cancer mutations | upper_lobe | 20 | 12 | 16828 | 4835 |
TP53,MET,CTNNB1,KRAS,FBXW7,AKT1,MAP2K1,PIK3CA,STK11,FGFR1,SMAD4,PTEN |
| 3.458e-03 | -5.67 | ANXA11 (annexin A11) | protein interactions | 311 | 94 | 39 | 19454 | 5460 |
PIR,RPA2,PDHA1,STX12,HNRNPH3,OTULIN,RAF1,TOP3B,TP53,PRDX3,CDC42,PGM1,SRI,ZDHHC17,RIGI,TFG,PLSCR1,SLC25A5,SIRT7,EWSR1,HSPA8,CISD1,OAT,TST,NQO1,PMM2,CD81,TOMM40,BAG3,PRDX2,LDHA,MIF,CDC5L,CCNF,S100A6,ENO2,ALG2,RNF208,CMBL |
| 3.458e-03 | -5.67 | KDM3B (lysine demethylase 3B) | protein interactions | 51780 | 94 | 39 | 19454 | 5460 |
PRMT5,ARL10,FABP5,OPTN,ESR2,VIRMA,EGLN3,MAD2L1,MAPRE2,AR,ZMYND11,XPO1,YWHAG,YWHAH,CUL3,CREBBP,MYC,MOV10,DNAJB6,CSTA,TRIM11,NUP50,BAG2,HSPA8,IDH3A,PML,S100B,RPA3,RNF41,NUCKS1,TOLLIP,KRAS,HSCB,SMYD3,SMAD1,TOP3B,MOB3C,ACACA,RPA2 |
| 3.458e-03 | -5.67 | TOM1 (target of myb1 membrane trafficking protein) | protein interactions | 10043 | 94 | 39 | 19454 | 5460 |
LITAF,TOLLIP,PDE2A,TFG,BAP1,HSPA8,EXOSC4,ZER1,DOHH,SSBP2,SOX2,ISG15,DAPK1,HNRNPL,PRNP,TAX1BP1,KCTD10,ILVBL,NAA11,EGLN3,SMURF1,ESR2,OPTN,LMBR1L,TSG101,CHAC2,RPS20,UBE2D1,WDR12,LRRC20,MYO6,CRMP1,SNX5,VAMP5,WWP2,FCGR2B,XPO1,USP14,AR |
| 3.458e-03 | -5.67 | DUSP1 (dual specificity phosphatase 1) | protein interactions | 1843 | 94 | 39 | 19454 | 5460 |
PSMD1,MAT2A,MTMR12,HNRNPAB,MRPS35,STAMBPL1,HSPB1,IKBKB,BLVRA,ABHD14B,SNX17,PTPN1,SYNCRIP,COX4I1,FBXO32,TMEM97,UBB,DUSP3,ECHDC1,HNRNPL,CCAR2,HDDC2,MRPL50,DUSP1,MAPK10,CKS1B,ILF2,MRPL49,NFE2L2,HSPB2,MTDH,PABPC1,PRPS1,POLR1H,MRPL17,PSMA1,SRM,STAU1,HNRNPK |
| 3.470e-03 | -5.66 | UNC45A (unc-45 myosin chaperone A) | protein interactions | 55898 | 209 | 77 | 19454 | 5460 |
SCLT1,CSNK1A1,RPA2,LMNA,CHMP1A,GABRA1,UBLCP1,DET1,DUSP22,CFTR,TPT1,KDM1A,LZTFL1,STAU1,FBXW7,AKAP1,STK26,BAP1,RPA3,NAPA,HSP90AA1,UBE2H,TLR9,UFD1,USP14,MYC,SUB1,CDKN3,CUL3,ROCK1,ZNF622,LMBR1L,CCNF,EIF4A3,PARP2,ILF2,PPME1,CAPZA2,FAF2,MAP1LC3B,KBTBD4,CSNK1E,MAX,TOP3B,RAF1,RNF20,FBXO25,PSMB10,HUWE1,PSMA5,CSE1L,POC1B,UBE3A,HNRNPA2B1,SMAD9,HDAC6,YWHAH,BTF3L4,MAP3K14,ERCC3,CMSS1,DIRAS2,EGLN3,CDK9,CDC5L,CHMP2A,CEP19,HSP90AB1,CDK17,TTC9C,IL18,DYNC1I2,TES,SEC23A,ATP6V1A,DFFA,FBXO32 |
| 3.470e-03 | -5.66 | XPOT (exportin for tRNA) | protein interactions | 11260 | 209 | 77 | 19454 | 5460 |
ARMC8,HSPB1,SLC2A1,RHOG,AGR2,HDAC6,DDRGK1,TRA2A,WDR11,DPP4,EGLN3,ILVBL,RHOH,KRT8,ETV6,CD274,PHB1,RNF126,RHOBTB1,HSPA13,NUP153,B3GNT2,COMTD1,FBXO25,NUP107,KRAS,PSMA1,RBCK1,HAPSTR1,NRP1,NTRK3,UBE2H,H2AZ2,BICD2,FBXO7,AR,MYC,PSMB2,PSMA4,GPR17,CUL3,APEX1,USP5,VIRMA,ARMC6,FBXO22,PTPMT1,LMBR1L,S1PR4,STUB1,CCNF,OPTN,PSMA6,RAN,PIH1D1,RPA2,HSP90B1,CDC42,RND2,CNPY3,CFTR,NUP62,BET1,FBXW7,HMGB1,MCMBP,DUSP26,STAU1,HDAC5,TXNL1,RAB9A,PSMA3,EP300,AKAP1,RHOU,RPA3,SIRT7 |
| 3.470e-03 | -5.66 | NR4A1 (nuclear receptor subfamily 4 group A member 1) | protein interactions | 3164 | 209 | 77 | 19454 | 5460 |
MTA2,LBR,EEF1A1,TRAF2,DDX39A,ESS2,TUBA1A,TP53,ABCC13,CCDC47,PRDX4,TFG,RTCB,HNRNPA2B1,PABPC1,FAF1,ID1,KPNA1,CRBN,CTNNB1,STK4,HDAC6,XPO1,CSNK2A1,NFKB1,HSP90AB1,DHX15,STK3,CCT7,DKC1,RPL7,TCP1,HNRNPL,FAM98A,SOCS4,FUBP3,SMAD3,RXRG,SYNCRIP,MED31,ZNF326,PPARG,CD2AP,HSPA5,BCL2A1,POLA2,PIAS1,PSMC1,STAU1,EP300,DDX5,HADHA,SQSTM1,RLIM,RTN4,PRDX6,HSPA8,HNRNPH2,PML,XRCC5,SMARCD3,ANKIB1,YWHAZ,GLOD4,CCT2,NONO,KPNA6,CUTA,SMARCE1,PRPF31,CDKN2D,AKT1,APEX1,TAB1,TMOD3,TUBA1B,PELP1 |
| 3.470e-03 | -5.66 | SLC2A12 (solute carrier family 2 member 12) | protein interactions | 154091 | 71 | 31 | 19454 | 5460 |
PARL,SPPL3,TAMM41,SERINC1,PTPMT1,SELENOT,SMAP2,TMEM164,FITM2,DNAJC19,DOLK,TMEM11,CHST11,SLC25A28,ORMDL3,TSPO,CERS6,GNL1,SLC25A51,RER1,BIRC2,SLC25A23,PIGW,SLC25A24,GHITM,HACD2,BCS1L,METTL15,COQ8B,TP53,SLC19A2 |
| 3.470e-03 | -5.66 | RAB34 (RAB34, member RAS oncogene family) | protein interactions | 83871 | 71 | 31 | 19454 | 5460 |
STAU1,DUSP21,RPA3,TMT1A,SNX11,WBP2,FLCN,AKAP1,LMNA,RPA2,SSR1,EPHX1,PLD3,CA8,SMAD1,ETF1,RALA,VIRMA,MAD2L2,NUP35,CCNF,PHB1,ENO1,SMAD4,RHOG,BRCA1,RHOB,SMAD2,MOV10,MYC,RAB11A |
| 3.470e-03 | -5.66 | TRAPPC8 (trafficking protein particle complex subunit 8) | protein interactions | 22878 | 71 | 31 | 19454 | 5460 |
GJA1,CMBL,TRAPPC10,TRAPPC3,TRAPPC6B,STX6,LAMP3,DNAJC5,LAMP2,RAB11A,TRAPPC4,YWHAB,SMAD4,LAMTOR1,TRAPPC2L,MIS12,RAB9A,TRAPPC1,RPA3,STX7,SSRP1,KRAS,BET1,EIF4B,TRAPPC3L,TRAPPC13,MYL6,FURIN,RAB4A,ACTR2,FGFR1 |
| 3.470e-03 | -5.66 | DENR (density regulated re-initiation and release factor) | protein interactions | 8562 | 71 | 31 | 19454 | 5460 |
VDAC2,CCNF,NFKBIA,COPS2,COPS7B,PRNP,CHGA,UBB,NTMT1,RPL10,ACAP2,COPS7A,COPS5,XPO1,HNRNPD,RB1CC1,RPA3,HNRNPA2B1,EWSR1,SLC25A32,KRAS,EIF2D,COPS4,RAF1,ATG16L1,SNRNP27,PPP1CB,MSX2,DMAP1,OXNAD1,CDK5R1 |
| 3.470e-03 | -5.66 | SLC35F2 (solute carrier family 35 member F2) | protein interactions | 54733 | 71 | 31 | 19454 | 5460 |
RAB11B,WDR44,APEX1,OPRL1,HNRNPL,SNX1,RETREG3,PCDH9,HRAS,REEP6,LAMP3,LAMP2,KDSR,RAB11A,CDSN,STX7,RER1,CMTM6,LPAR1,BSCL2,VIPR1,TEX264,TSPAN15,ATP5PF,KLRC2,JUP,SURF4,CTBP1,TFRC,SIGMAR1,TP53 |
| 3.470e-03 | -5.66 | CX3CL1 (C-X3-C motif chemokine ligand 1) | protein interactions | 6376 | 71 | 31 | 19454 | 5460 |
JAK1,STX8,BMPR1A,STX7,SGMS2,FTSJ1,PIK3R2,SLC29A1,IFNGR1,GOSR2,UGCG,CERK,CX3CR1,STX5,WDR44,SRC,NOP9,CX3CL1,NDFIP1,CSGALNACT2,TENM3,SLC30A5,RHOBTB3,ORC5,PIK3R3,C1GALT1C1,NUS1,SLC20A1,ATP1A3,TMEM11,WDR20 |
| 3.482e-03 | -5.66 | MSTO1 (misato mitochondrial distribution and morphology regulator 1) | protein interactions | 55154 | 57 | 26 | 19454 | 5460 |
CCT2,F9,LAMP2,GPR17,P2RY10,RUNX1,RBIS,EGLN3,CCNF,PHB1,FBXO32,OLFM2,ARHGAP25,ACACA,RAF1,COMTD1,RBBP7,NPTN,SEMA4C,RBCK1,IMMP2L,RPA3,CCT8,EFNB1,EP300,UBE3A |
| 3.482e-03 | -5.66 | TIGAR (TP53 induced glycolysis regulatory phosphatase) | protein interactions | 57103 | 57 | 26 | 19454 | 5460 |
DNAJB4,HINT1,NANP,RPA3,HSPA5,GUK1,HSCB,ETFA,TP53,CCR1,MSRB3,PIH1D1,RPA2,GLTP,UBE2L3,NUP35,NMI,TRIM35,AKR1C2,HNRNPL,LYRM2,MTPN,PNPLA4,WWP2,AGPAT1,GSTO1 |
| 3.482e-03 | -5.66 | ZNF771 (zinc finger protein 771) | protein interactions | 51333 | 57 | 26 | 19454 | 5460 |
KRR1,PRKRA,RPS10,RPL7,RPL13A,RPL19,SURF6,CUL3,RPL6,RPL7A,E4F1,RPS2,H1-1,PPAN,RPL3,RPL23A,DGCR8,H1-6,MRPS17,SRSF4,RPL28,RPL17,RIGI,NOTCH2,ZNF574,RPL18 |
| 3.482e-03 | -5.66 | GEMIN8 (gem nuclear organelle associated protein 8) | protein interactions | 54960 | 57 | 26 | 19454 | 5460 |
SNRNP70,MYO6,HAX1,NCKIPSD,DDRGK1,SNRPB,SNRPD3,DYRK1A,ESR2,SNRPD2,PHAX,LSM2,SIGLECL1,P2RY12,SNRPE,GEMIN7,SNRPN,COMTD1,FAXC,LSM4,KRAS,SNRPG,SMN1,SNRPA,BAP1,CD40 |
| 3.482e-03 | -5.66 | RBSN (rabenosyn, RAB effector) | protein interactions | 64145 | 57 | 26 | 19454 | 5460 |
ACACA,RAB4A,DISC1,PDHA1,FGFR1,VPS33A,RPA2,EHD3,EHD1,MYH1,TP53,ATG16L1,STX7,RAB5A,HSPA8,RPA3,EHD4,DNAJC5,YWHAH,RAB22A,RAB5C,ATG9A,LAMP2,RAB2A,RAB14,KTI12 |
| 3.482e-03 | -5.66 | DMXL1 (Dmx like 1) | protein interactions | 1657 | 57 | 26 | 19454 | 5460 |
CCNF,RAB35,RAP1B,STX6,VIRMA,ATG9A,LAMP2,H2AC14,OST4,RAB11A,ROGDI,STK4,LAMTOR1,DCAF4,DNAJC7,RAB5A,PDIA6,RAB9A,RAB3B,ATP6V1G2,STX7,ATP6V1G1,BET1,RPA2,RPN1,RAB4A |
| 3.482e-03 | -5.66 | LEF1 (lymphoid enhancer binding factor 1) | protein interactions | 51176 | 57 | 26 | 19454 | 5460 |
ALYREF,SMAD3,STUB1,RB1,EP300,HINT1,RUVBL1,MITF,KPNA2,SUMO2,MLH3,STAT5A,EGLN3,TLE1,PRMT6,RNF14,CTNNB1,SMAD1,BTF3,NFE2L2,SMAD4,SMAD2,KPNA1,FHIT,BAX,STK11 |
| 3.483e-03 | -5.66 | regulation of transforming growth factor beta receptor signaling pathway | biological process | GO:0017015 | 179 | 70 | 18204 | 5365 |
TWSG1,SAP30,SDCBP,EP300,IL17F,SPRED1,PEG10,RBBP7,MIR101-1,BRMS1L,SMAD3,TP53,ZNF451,RBBP4,FLCN,MIR145,MIR302B,SPRED2,MIR490,MIR9-1,ING1,MIR142,STUB1,PBLD,FAM89B,TGFB3,SPRY1,MIR98,USP15,MIR140,STK11,PPARA,MIR361,CREBBP,SMAD4,FOLR1,SIN3A,FKBP1A,TGFB1I1,MIR204,BCL9,CAV2,EID2,LEMD3,SAP30L,HSP90AB1,MIRLET7G,MIR424,CITED1,ING2,CAV3,DKK3,LDLRAD4,MIR20A,SMURF1,MIR17,HTRA1,HSPA5,NREP,BRMS1,MIR342,SMAD2,MIR373,MIR106A,PPARG,MIRLET7B,MIR30B,MIR21,MIR497,CHST11 |
| 3.503e-03 | -5.65 | SMALL_CYTOKINES_CC | prosite domains | PS00472 | 23 | 13 | 12186 | 3388 |
CCL5,CCL23,CCL3,CCL4L1,CCL2,CCL1,CCL28,CCL11,CCL19,CCL8,CCL20,CCL17,CCL18 |
| 3.504e-03 | -5.65 | chromaffin granule membrane | cellular component | GO:0042584 | 9 | 7 | 19108 | 5553 |
ATP8A1,SYT2,CYB561,DBH,SRI,DNAJC5,ANXA7 |
| 3.513e-03 | -5.65 | DNA deamination | biological process | GO:0045006 | 13 | 9 | 18204 | 5365 |
APOBEC3B,APOBEC3G,APOBEC3H,EXOSC3,APOBEC3C,EXOSC4,APOBEC3D,APOBEC3A,APOBEC3F |
| 3.513e-03 | -5.65 | protein insertion into mitochondrial inner membrane | biological process | GO:0045039 | 13 | 9 | 18204 | 5365 |
TIMM13,TIMM8B,TIMM29,TIMM8A,TRMT10B,TIMM10,AGK,TOMM70,ROMO1 |
| 3.513e-03 | -5.65 | negative regulation of response to drug | biological process | GO:2001024 | 13 | 9 | 18204 | 5365 |
MIR9-1,MIR185,MIR1-1,MIR873,MIR129-1,MIR133B,MIR186,MIR495,MIR34B |
| 3.513e-03 | -5.65 | negative regulation of amyloid fibril formation | biological process | GO:1905907 | 13 | 9 | 18204 | 5365 |
PFDN1,CLU,PFDN2,PFDN6,PFDN4,PFDN5,LDLR,MIR31,CRYAB |
| 3.513e-03 | -5.65 | negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane | biological process | GO:1905700 | 13 | 9 | 18204 | 5365 |
MIR9-1,MIR185,MIR1-1,MIR129-1,MIR873,MIR133B,MIR34B,MIR186,MIR495 |
| 3.513e-03 | -5.65 | maintenance of protein localization in endoplasmic reticulum | biological process | GO:0035437 | 13 | 9 | 18204 | 5365 |
HSPA5,RER1,KDELR2,PDIA2,KDELR1,GPAA1,FKRP,OS9,INSIG2 |
| 3.513e-03 | -5.65 | regulation of xenobiotic detoxification by transmembrane export across the plasma membrane | biological process | GO:1905699 | 13 | 9 | 18204 | 5365 |
MIR873,MIR129-1,MIR1-1,MIR186,MIR495,MIR34B,MIR133B,MIR9-1,MIR185 |
| 3.513e-03 | -5.65 | signal peptide processing | biological process | GO:0006465 | 13 | 9 | 18204 | 5365 |
IMMP2L,HM13,SPCS1,SPCS2,PARL,SPPL3,SPCS3,FURIN,SEC11A |
| 3.513e-03 | -5.65 | regulation of endosome size | biological process | GO:0051036 | 13 | 9 | 18204 | 5365 |
RAB11A,BORCS8,RAB5A,KXD1,BLOC1S2,BORCS6,BORCS5,BORCS7,SNAPIN |
| 3.513e-03 | -5.65 | cellular response to potassium ion | biological process | GO:0035865 | 13 | 9 | 18204 | 5365 |
SLC12A2,MECP2,DLG4,NPTX1,NEK7,CYP11B1,KCNJ10,CYP11B2,CRHBP |
| 3.520e-03 | -5.65 | PLCB3 (phospholipase C beta 3) | protein interactions | 5331 | 97 | 40 | 19454 | 5460 |
PLCB1,RAMAC,ANAPC16,LPAR2,XRCC5,LIN7C,DNAJC3,NUDT5,RPA3,FTL,MRPS18C,ROCK2,KRAS,KDM4B,CAMK2G,SMYD3,MND1,ATP5PB,NAA16,AP2S1,PARD6A,HNRNPH3,NHERF1,KRIT1,DMAP1,RAC2,PLCB2,ADD1,ZNF174,SYNCRIP,HRAS,VIRMA,JUNB,UBA3,ROCK1,TYW3,MOV10,FGFR1OP2,CAMSAP2,SNTA1 |
| 3.521e-03 | -5.65 | hexose biosynthetic process | biological process | GO:0019319 | 52 | 25 | 18204 | 5365 |
SLC25A10,PGM1,CRY1,SLC25A11,LEPR,G6PC3,SLC25A1,PC,FBP2,CRTC2,PGK1,ATF3,AKR1B1,FBP1,MDH1,PPARA,ENO2,SORD,ATF4,PCK2,SLC37A4,PGAM1,ENO1,SLC25A12,SDS |
| 3.521e-03 | -5.65 | positive regulation of vascular associated smooth muscle cell proliferation | biological process | GO:1904707 | 52 | 25 | 18204 | 5365 |
SRC,MIR222,GNAI2,GJA1,MIR208A,MIR20A,JUN,MIR214,MIR17,MIR21,MIR146A,MIR130A,MIR221,BMPR1A,IL10,IGF1,JAK2,TNF,MDM2,MIR448,ADAMTS1,MIR135B,MMP9,MIR301A,TERT |
| 3.530e-03 | -5.65 | Signaling by Insulin receptor | REACTOME pathways | R-HSA-74752 | 322 | 124 | 10285 | 3229 |
PSMD3,JAK2,PSMB7,PIK3R1,PSMB1,PSMA3,PSMB5,PSMC4,PSMA4,IL2,PSMC5,FGFR1,PSMB11,PSMB10,PSMB6,PSMA2,DLG4,RHEB,BRAP,CSK,SPTBN1,PPP5C,ANGPT1,PSME1,PSMD7,ATP6V1G1,ATP6V1E2,FGF17,PSMD14,PTPN11,STK11,UBB,PPP2R1A,CAB39,CSF2,ATP6V0B,FGF7,JAK1,LAMTOR1,PSMD12,AKT2,EIF4B,RRAGA,SHC3,RAP1A,FGF3,PSME2,PSMD6,HBEGF,PSMB9,SPRED2,IL2RA,MAP3K11,RRAGB,NEFL,DUSP10,PIK3R2,IL2RG,YWHAB,GRB10,DUSP6,PPP2R5A,FGF1,STRADB,MET,PAQR3,FGF23,PSMA5,SPTAN1,TLR9,ATP6V1C1,EIF4E,PPP2R5E,PSMB3,PEBP1,PSMD10,FRS3,SRC,DUSP9,FGF10,RAP1B,MAP2K1,KRAS,UBA52,ATP6V0E1,FGF22,WDR83,RAF1,FGF16,IL2RB,CAMK2G,LAMTOR3,VWF,PRKAG1,CUL3,PSMC1,GAB1,HRAS,KIT,LAMTOR2,PPP2CB,IL5,PSMD1,PSMB2,AKT1,PSMA6,PEA15,PIK3CA,ATP6V1G2,RASGRP3,SHC1,PSMB4,ATP6V1A,SEM1,ATP6V1D,DUSP1,PRKAB1,PSMC3,PSMA1,IL3,RPS27A,SPRED1,PSMD4,PHB1 |
| 3.538e-03 | -5.64 | proton-transporting two-sector ATPase complex | cellular component | GO:0016469 | 50 | 24 | 19108 | 5553 |
ATP6AP2,ATP6V1D,ATP6V1E2,ATP5PF,ATP6V1G1,PPIF,ATP5MC1,ATP5MK,ATP6V0B,ATP6V1A,ATP5F1D,ATP6V1G2,ATP5F1E,RNASEK,ATP5PO,ATP6V0E1,TMEM199,ATP5MC3,ATP6V1C1,ATP5F1A,ATP5MG,ATP5PB,ATP5PD,ATP5F1B |
| 3.551e-03 | -5.64 | ELP1 (elongator acetyltransferase complex subunit 1) | protein interactions | 8518 | 166 | 63 | 19454 | 5460 |
PRDX1,IRF4,MAP3K14,MPG,IKBKB,ELP6,SHC1,HAX1,FAM219B,FBXO32,PSMB5,SDHAF2,KRT8,EGLN3,CDC5L,RAF1,CCT5,SNAPIN,APEH,FHL3,PSMA2,DCP2,KRAS,PSMD12,MCM6,MYC,CUL3,CIAO1,MCM4,RIT1,UBE2H,CCNF,LMBR1L,NFKBIA,KTI12,PSMC5,PTEN,PSMD4,PPP5C,VIRMA,PSMC4,ATG16L1,CD2AP,PLP2,ELP3,RPA2,UBE2M,ACACA,ARCN1,PIH1D1,RPA3,DUSP9,SIRT7,SF3B1,P4HA2,EP300,DPH3,NUP50,TTR,FBXW7,STAU1,PSMC1,FTL |
| 3.551e-03 | -5.64 | RXRA (retinoid X receptor alpha) | protein interactions | 6256 | 166 | 63 | 19454 | 5460 |
CSNK2B,PSMC5,UBE2I,TRIM24,NFKBIB,NR1I2,GADD45G,PPP5C,TAF11,SRC,MATR3,STAT1,NR1H2,NONO,TRIM32,CREBBP,SMAD2,SP1,LMNB1,ZNHIT3,TADA3,EP300,SQSTM1,NR1I3,SMARCD3,PML,NRBF2,HDAC3,EDF1,IGFBP3,PRMT2,PPARG,MED23,FGFR1,COPS2,RXRG,MIOS,HNRNPL,NR2F6,CTNNB1,MPG,TPM3,HMGA1,NFKB1,PIK3R1,NR4A2,TRAF6,CASTOR2,TRIP4,BHLHE40,GADD45A,SMN1,CAPZA1,KRAS,ZBTB16,ACVR1B,PPARA,MECR,TRAF2,VDR,SMARCB1,RNF8,ACVR1 |
| 3.551e-03 | -5.64 | SLK (STE20 like kinase) | protein interactions | 9748 | 166 | 63 | 19454 | 5460 |
SAP18,PPP1R2,STAU1,PITHD1,NSFL1C,HSPA8,EP300,SQSTM1,RPA3,BAP1,EIF4B,BORCS8,PRKCA,RPA2,PSMB7,MAP2K1,PPP1CB,SNRNP27,VIRMA,MED17,ADRM1,PSMC5,CCNF,TNFRSF1B,PDCD4,UBE2H,PIP4K2C,RHOB,YWHAZ,DNAJC8,MCM3,NONO,ST13,SFN,SUB1,HNRNPF,PSMA1,MAPK1IP1L,RUVBL1,TTC4,RUVBL2,RPAP3,BAG2,CCR1,HGS,KIF2A,GTF2E2,ATP5PB,WDR44,CDC5L,ZBTB2,OSBP,SNX1,AIFM1,GYS1,MED4,MAP4,YWHAB,PSMD10,HNRNPA1,COPS5,YWHAG,PPP2R5A |
| 3.552e-03 | -5.64 | UBIQUITIN | prints domains | PR00348 | 11 | 8 | 5227 | 1528 |
FAU,ISG15,UBB,RPS27A,NEDD8,UBA52,UBL4A,UBTD1 |
| 3.560e-03 | -5.64 | SMAD3 (SMAD family member 3) | protein interactions | 4088 | 432 | 147 | 19454 | 5460 |
CDC16,AKT1,ALKBH2,SUB1,RUNX1,AR,LACRT,DEDD,SMAD2,STUB1,PSPC1,TRIM24,BUB3,PLAGL1,SMURF1,JUNB,SMAD5,DYRK1A,PCK2,SF3A1,ATG16L1,SPTBN1,HYAL2,EID2,LMNA,DDX4,WWP1,METTL14,RPLP0,GIT2,LEMD3,APMAP,PML,ARHGEF6,SQSTM1,NF2,IRF7,RPL4,AATF,USP2,HP,ZMYND11,TPM3,SUV39H1,SMAD4,SNRNP70,ID1,USP15,SMAD3,TFE3,PSMB1,PLG,PRNP,CDK9,SLC25A12,TP53,CDK4,YTHDF2,HINT3,TRIM62,MAP2K3,SMAD1,ZDHHC4,SOX9,CDK8,PIK3CA,FURIN,TAF2,DDR1,MYD88,TLR4,TMED1,RPL3,TGIF2,IGF1R,SERTAD1,CAMK2G,TGFBR2,CSH1,TF,HNRNPK,BACH1,RIGI,CREBBP,MYC,RIOK2,PROX1,BAG3,BRCA1,DCAF4,CXXC5,SP1,RIT1,RRAS2,ZMYM2,ACTB,ESR2,RASL12,TANK,CDKN1A,PPARG,VAV2,GTF2IRD1,EIF4B,VSIR,FOS,XRCC5,HDAC5,EP300,CFDP1,DDX5,TGFB1I1,SKP1,WWP2,CTNNB1,KDM2A,CBL,SMAD9,MED4,SIN3A,RGCC,TCP1,MAX,VDR,NAA15,E2F4,JUN,KCTD16,NUP153,PPP2R1A,EZH2,MTA2,HGS,CPTP,TRIP4,PABPC1,ATF3,JAK1,DNAJB4,LDLRAD4,PRDM4,FHL3,ZBTB16,RCVRN,ACVR1B,PAEP,PAX6 |
| 3.560e-03 | -5.64 | leukocyte chemotaxis | biological process | GO:0030595 | 147 | 59 | 18204 | 5365 |
CXCR1,CCL23,PPIB,IL1B,SCG2,CCL3,MSMP,CH25H,SYK,HMGB1,PDE4B,CXCL1,PIK3CG,CXCR4,S100A8,CCR7,CCL8,FOLR2,CCL11,CCR6,XCL1,IL10,FCER1G,TGFB2,CX3CL1,CCL5,CXCL8,DPEP1,CXCL9,CXCL11,CCL24,PPIA,IL6,CX3CR1,SLC12A2,KIT,CCL1,CCL25,CCR5,CCL21,CKLF,RPL13A,NINJ1,CXCL3,ADGRE2,PTN,SFTPD,CCL19,CCR2,JAML,CXCL13,CCL2,SRP54,LGALS3,CXCL10,CCL4L1,CCR1,CHGA,CCL18 |
| 3.571e-03 | -5.63 | membrane assembly | biological process | GO:0071709 | 60 | 28 | 18204 | 5365 |
PTEN,CAV1,REEP3,CHMP2A,SPTBN1,NLGN1,CAV2,CHMP2B,CHMP1A,CAV3,VPS4A,UBXN2B,UGCG,HDAC3,EMP2,TLCD2,NSFL1C,CHMP5,CHMP1B,NLGN2,CHMP4C,S100A10,TLCD1,VPS4B,UBE2I,REEP4,BANF1,FLOT1 |
| 3.571e-03 | -5.63 | proteoglycan biosynthetic process | biological process | GO:0030166 | 60 | 28 | 18204 | 5365 |
BMPR1B,CHST10,IGF1,CHPF,CHST9,NDST3,CHST13,EXTL2,BMPR2,HS3ST1,GLCE,NDST1,B4GALT7,CSGALNACT1,EXT1,HS3ST5,FAM20B,CSGALNACT2,PXYLP1,GAL3ST4,HS2ST1,CYTL1,CHPF2,UST,HS3ST3A1,UGDH,CHST7,CHST11 |
| 3.574e-03 | -5.63 | Ubiquitin_dom | interpro domains | IPR019956 | 11 | 8 | 18521 | 5414 |
UBA52,FAU,UBTD1,UBL4A,UBB,NEDD8,RPS27A,ISG15 |
| 3.574e-03 | -5.63 | Band_7 | interpro domains | IPR001107 | 11 | 8 | 18521 | 5414 |
PHB1,ERLIN2,STOML2,FLOT1,PHB2,STOML3,ERLIN1,STOM |
| 3.575e-03 | -5.63 | ACTR10 (actin related protein 10) | protein interactions | 55860 | 100 | 41 | 19454 | 5460 |
BMERB1,RIT1,MAPRE1,CCL4L1,LMNB1,BTF3,BCL7C,CENPW,MED22,RAB11A,UQCRH,DYNLL1,DYNC1I2,ACTB,COPS2,CXCL14,ZNF574,RNF181,DCTN4,TUBB4B,SKA3,CAPZA2,SOX2,ANAPC13,ACTR1A,PPP2R1A,SPMIP6,AKR7A2,PAFAH1B1,CA10,IMMP2L,CAPZA1,KRAS,TRA2B,DYNC1I1,EXOSC4,ACTR1B,DCTN3,ORC6,BAP1,DCTN6 |
| 3.575e-03 | -5.63 | MED29 (mediator complex subunit 29) | protein interactions | 55588 | 100 | 41 | 19454 | 5460 |
BIRC5,MED31,POLR2D,POLR2G,POLR2C,BEND6,MED23,CDK8,NRDE2,MED30,FBXL19,DDX39A,MED9,ATG16L1,SSNA1,OIP5,FBXW7,MED11,MED13L,PRKD3,MED4,SMAD9,STN1,CHCHD4,MED29,MED21,MED10,MED27,ZCCHC10,MED22,MOV10,SMAD5,POLR2B,POLR2I,MED17,SPPL3,DNAJC1,GTF2F2,POLR2F,POLR2L,ENO1 |
| 3.575e-03 | -5.63 | ECE1 (endothelin converting enzyme 1) | protein interactions | 1889 | 100 | 41 | 19454 | 5460 |
STX7,CD1B,CLEC12B,RAB5A,MTDH,NPB,RAB9A,CST11,CLK1,TMEM106B,NCR3,FKBP10,AQP3,RAB4A,SFTPC,FAF2,TMEM106A,CLEC2B,RPSA,FUT8,TOP3B,COMTD1,VIRMA,RPL19,CAV1,DUOXA2,LGALS3,ARF6,ST8SIA5,RAB35,RPS26,LGALS8,BICD2,SDF2L1,LAMTOR1,DNAJC5,LAMP3,RAB5C,LAMTOR2,RAB11A,RAB2A |
| 3.575e-03 | -5.63 | MTCL2 (microtubule crosslinking factor 2) | protein interactions | 140710 | 100 | 41 | 19454 | 5460 |
ANKRA2,VIRMA,ESR2,EGLN3,RORB,DYNLL1,HNRNPL,KRT8,GSK3A,YWHAB,CAMSAP2,TSNAX,COP1,YWHAZ,PSMD14,SMAD4,YWHAG,YWHAH,SAMHD1,PPP2R5A,CUL3,NDC80,SFN,RNF41,STX11,KDM1A,RNF113A,BHLHE40,SIRT7,TRIM36,TFIP11,PNMA2,VPS33A,BORCS6,PPP2R1A,RFXANK,SOX2,JUN,FAM161A,ZNF263,RAF1 |
| 3.575e-03 | -5.63 | ACOX1 (acyl-CoA oxidase 1) | protein interactions | 51 | 100 | 41 | 19454 | 5460 |
PHYH,TMED9,GPX1,RAB11B,GSTA1,ENO2,ACBD7,PNMA1,LHFPL4,CHCHD4,LACRT,SMAD4,TXNRD2,PTDSS1,COX6B1,HNRNPF,LITAF,HSCB,PPWD1,CDKN2C,SFXN1,RPA3,IDH1,ARPC2,RAB30,ACTR2,RAB6B,STX17,RPA2,FOXS1,RPLP0,SLC25A20,CCR1,FAM136A,EFHD1,RAF1,LAP3,DUSP14,NUP62,MRPL12,CRAT |
| 3.581e-03 | -5.63 | PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1) | protein interactions | 5562 | 253 | 91 | 19454 | 5460 |
DVL2,RPA3,FBXW7,PFKFB2,EIF5B,CERS2,CFTR,PTP4A2,RPRD1B,RPA2,ACACA,SCLT1,MID1IP1,DCLRE1C,CCNF,OPTN,TRIM27,CAB39,MRPS21,TRAF1,SRPK2,SUB1,SPRED1,AGAP2,TXNIP,UBE2H,STK11,BHLHE40,SLC6A3,ADIPOQ,CDK4,TP53,THAP1,TRAK2,MCL1,EDEM1,USP2,LAMTOR2,SHC1,BECN1,SMAD4,CRBN,SSX2IP,SNRK,DUSP9,NUP50,EP300,HDAC5,HSPA8,STAU1,FXR2,SLC31A1,PRKAB1,ARMCX3,CTBP1,PPARG,AKR1A1,BAD,NTNG2,RPL35,LAMTOR3,MORC4,SFN,CUTA,YWHAZ,LAMTOR1,NTRK3,HSP90AA1,ZBED1,G3BP1,FANCG,PNMA5,RAF1,TULP3,ASPM,TUBA1A,CRTC2,TRAF2,PRKAG1,CPE,POLR2C,ATP6V1A,MAP1LC3A,HSP90AB1,INO80E,YWHAH,TRAF6,YWHAB,BCL2L1,PDAP1,SPHK2 |
| 3.583e-03 | -5.63 | regulation of mitotic cell cycle phase transition | biological process | GO:1901990 | 360 | 130 | 18204 | 5365 |
ACTL6A,CDK1,MTA3,BTN2A2,KLF4,PHB2,CDK6,JADE1,CTDSP2,SMARCE1,BIRC5,ACTL6B,MIR133B,MDM2,DTL,ZNF207,CDC23,LCMT1,ERCC3,CDC16,UBE2E2,CDK2AP2,TP53,IER3,ANAPC4,VPS4A,FZR1,CDC20,TMEM14B,MIR15A,PLCB1,MIR208A,KLHL22,SMARCD3,CDKN1B,CUL3,MIR193A,GPNMB,RGCC,BRCA1,LSM10,CHMP4C,PSME2,CCNB1,CDC73,MIR519D,ECD,NBN,RPS27L,MAD2L2,MNAT1,RAD21,MEPCE,FBXO7,MIR638,MIR137,SIN3A,RBBP8,RRM1,WNT10B,NDC80,SMARCB1,MIR195,MAD2L1BP,CDKN2D,TPRA1,BABAM1,MIR29A,ANAPC15,EZH2,MIR495,RINT1,BCL7B,CDC7,FAM107A,NUF2,AKT1,NOP53,TOPBP1,VPS4B,RPL26,PKIA,ACTB,CRLF3,FGF10,CDKN2C,SPC24,TMOD3,FBXO31,ADAMTS1,RPA2,DUSP1,CCND3,RAB11A,RIOK2,BUB3,MIR214,CCNH,MIR222,ACVR1,NAE1,PSME1,CTDSP1,CCND1,PSMG2,MIR221,AIF1,CDK7,CYP1A1,BCL7C,CDK4,DLG1,NABP1,MIR29C,PTEN,CCL2,MAD2L1,PML,CDKN1A,ANAPC11,CDK5RAP3,DCUN1D3,CACNB4,MIR16-1,TERT,ZNF655,PRMT2,CRADD,IK,RB1 |
| 3.583e-03 | -5.63 | HEATR3 (HEAT repeat containing 3) | protein interactions | 55027 | 163 | 62 | 19454 | 5460 |
SDHB,AIFM1,PTPN1,ST6GAL1,ESD,VTI1B,DNAJC1,HNRNPA1,FEM1B,DDRGK1,COX5A,FAM174A,HNRNPD,TST,NCK1,EFNB1,DHX9,GLCE,CD83,ATP5PF,MEPCE,IMMP2L,SEMA4C,MAP1LC3B,TRMT1L,COMTD1,CHRM3,ETFB,CTXN1,GLE1,SIGLECL1,ACAT1,SCN2B,LMBR1L,CCNF,SURF2,CHRM4,PSMA6,LDHA,ST13,NONO,NDUFAF2,AKT1,GPR17,LDHB,TMED4,OAT,HADHA,MAVS,DLAT,RPA3,LRP10,TSR3,HNRNPA0,HSCB,SEC62,HCST,FAM234A,PIP5K1A,SDC2,ATP5PO,RPA2 |
| 3.603e-03 | -5.63 | positive regulation of DNA metabolic process | biological process | GO:0051054 | 299 | 110 | 18204 | 5365 |
RNF8,STAT6,GREM1,INO80E,CCT8,CCT7,CREBBP,CDC7,UBE2V2,RFC2,TOP2B,BCL7B,HMGB1,CD40,AKT1,INO80C,DHX9,KMT5B,SHLD1,PCNA,HNRNPD,CTNNB1,FGF10,RFC5,TFRC,RPS3,RUVBL1,TNF,PARM1,RFC3,DKC1,ACTB,STN1,IL2,UBE2N,XRCC5,BCL7C,HNRNPAB,TNFSF13,NEK2,CEBPG,CYP1B1,H2AX,STPG4,RNF126,SMCHD1,ATF1,TNFAIP1,CCT2,MORF4L1,CDKN1A,MAPKAPK5,FAM168A,PML,PKIB,RFC4,HSP90AA1,KLF4,EYA3,PELI1,HNRNPA2B1,TFPT,SLX1A,SMARCE1,MGMT,PTGES3,FGFR1,ACTL6A,SSBP1,WRAP53,SMARCA5,CDK1,DMAP1,HTR2A,IL6,IGF1R,MYC,VPS72,BAX,NEK7,CDC42,ACTL6B,HNRNPA1,CCT5,TCP1,TNKS2,NBN,ACTR2,PPP1R10,CCNA2,CDKN1B,SMARCD3,IL4,BRCA1,UBE2B,RGCC,PRKCQ,HSP90AB1,CD28,BABAM1,FAF1,UCN,EXOSC3,RUVBL2,PRIM2,HMCES,MAD2L2,MEAF6,SMARCB1,TNKS |
| 3.612e-03 | -5.62 | transcription regulator complex | cellular component | GO:0005667 | 506 | 175 | 19108 | 5553 |
CTNNB1,CCNH,SIX5,STAT1,FOS,MED31,RFX5,LDB2,STAT6,EP300,TRIP4,CBX3,E2F4,NFIL3,NFKB1,MYC,SMAD9,ATF3,JUN,MSX1,RBBP4,RBBP8,HLF,CDK4,TP53,RXRG,XBP1,PHF12,HMGA1,SOX9,BATF,GTF2E2,STAT2,GTF3C3,IRF9,HDAC3,HNRNPAB,PAAF1,PKNOX1,NR4A2,AATF,GTF2E1,TAF1D,ASCC1,GMNN,CTNNBIP1,ERCC3,GTF2H5,GTF2A2,GTF2F2,TLE1,FOSL2,SIN3A,NFE2,NONO,MED22,KDM1A,DHRS7B,TCF21,LDB1,SMAD3,HAND2,MTA2,ENY2,RBPJ,CREB3,E2F6,HCLS1,CBX5,RBBP7,CCND1,BARX2,C1D,TAF7,CDK2AP2,MAX,HMGB1,MDM2,RB1,NFE2L2,SMAD5,KLF4,CDK7,SDR16C5,CTBP1,HEY2,ATF4,GTF2F1,CEBPG,DR1,DRAP1,HAX1,LMO2,NR1H2,CREBBP,GTF2H4,SSBP3,CEBPE,GFI1,SNAPC3,MSX2,MED11,RFXANK,STAT5A,RUNX1,MED10,INSM2,SOX2,SUPT3H,TFDP2,PPARG,SNAPC1,CBFB,VDR,NAA16,MIDEAS,SOX14,TAF5L,ING2,TAF11,HELT,MTA3,CREB1,MNAT1,MXD1,NR1I2,MED21,RLIM,ZBTB16,TCEA1,HOXD12,IVNS1ABP,SP1,TADA3,MED17,ADNP,MAFG,BACH1,RIOX2,MEF2A,TAF2,SNAI3,MXI1,SMAD2,MED9,NFYA,SUB1,MED30,ATF1,MED4,NFYB,SMAD4,MED29,SMAD1,GTF2A1,TAF10,HYAL2,BCL9,TAF9,GTF2B,LMO4,S100A10,NAA15,JUNB,HNF1B,MED23,GTF3C4,MBD3,MED27,DDIT3,LBX1,MEF2B,GTF2H2,RFXAP,CREBZF |
| 3.613e-03 | -5.62 | Interleukin-2 signaling | REACTOME pathways | R-HSA-451927 | 262 | 103 | 10285 | 3229 |
PSMB9,IL2RA,SPRED2,PSMD6,HBEGF,FGF3,PSME2,NEFL,DUSP10,MAP3K11,PSMD12,FGF7,JAK1,PIK3R3,CSF2,RAP1A,SHC3,PSMD7,FGF17,ANGPT1,PSME1,SPTBN1,PPP5C,UBB,PPP2R1A,STAT5A,PSMD14,PSMC4,PSMA3,PSMB5,PIK3R1,PSMB1,PSMD3,INPPL1,JAK2,PSMB7,DLG4,BRAP,CSK,PSMA2,PSMB6,FGFR1,PSMC5,IL2,PSMB11,PSMB10,PSMA4,DUSP1,SEM1,PSMB4,SHC1,RASGRP3,SPRED1,PSMD4,PHB1,IL3,RPS27A,PSMA1,PSMC3,CUL3,PSMC1,VWF,IL2RB,LAMTOR3,CAMK2G,FGF16,PSMA6,PEA15,PIK3CA,PSMB2,PSMD1,HRAS,LAMTOR2,PPP2CB,KIT,IL5,FGF10,SRC,DUSP9,PSMD10,FRS3,RAF1,UBA52,SYK,FGF22,WDR83,MAP2K1,KRAS,RAP1B,DUSP6,PPP2R5A,FGF1,YWHAB,IL2RG,PIK3R2,PSMB3,PEBP1,SPTAN1,PPP2R5E,FGF23,PSMA5,MET,PAQR3 |
| 3.614e-03 | -5.62 | TRIM69 (tripartite motif containing 69) | protein interactions | 140691 | 74 | 32 | 19454 | 5460 |
SYNE4,TRIM54,PPP1R18,UBE2N,TRIM44,GJA1,TLR9,UBE2D1,ATP5MC1,BLOC1S5,UBE2H,FKBP1B,CSK,BAG3,NTAQ1,TRIM63,UBE2D3,RIGI,TNNT2,CDSN,RINT1,PML,TLR4,BLOC1S2,MAGEA4,TLR3,HGS,FAM161A,TP53,RRM1,SNAPIN,DDX39A |
| 3.614e-03 | -5.62 | DDX55 (DEAD-box helicase 55) | protein interactions | 57696 | 160 | 61 | 19454 | 5460 |
CRLF3,ATG3,MRPS25,RC3H2,RIT1,MYC,SNX3,RPL13A,ESR2,RPL10,RPL19,RPS3,MID1IP1,ZNF330,PRKRA,FGFBP1,MRPS34,APOBEC3C,RPA2,HEXIM1,RPL26L1,ATG16L1,MTMR6,AGTRAP,RBMS2,FGF13,UFL1,STAU1,UTP23,RPA3,EP300,DDX23,DRG2,NOL12,KPNA1,RPL23,IFI16,GRSF1,ATG7,DDRGK1,RPS10,FZR1,RPS16,CAND1,MRPS23,KRR1,LLPH,RPL15,KRAS,TOLLIP,RPL28,MRPS17,PTGES3,RPL31,RPL23A,SETD4,RPL3,MRPS18B,PICK1,MRPS11,RPS24 |
| 3.619e-03 | -5.62 | Platelet activation, signaling and aggregation | REACTOME pathways | R-HSA-76002 | 282 | 110 | 10285 | 3229 |
FAM3C,GP9,VWF,IL2RB,TMX3,AKT3,GNAI3,AKT1,PIK3CA,TGFB3,TIMP3,TF,GNA14,IL5,RHOB,GNG11,VEGFA,TMSB4X,SHC1,MIR197,RARRES2,IL3,CD9,CFL1,PTPN1,HSPA5,CYRIB,RHOG,PROS1,CDC42,PLG,LHFPL2,CDC37L1,IL2RG,PIK3R2,CHID1,MAGED2,GNG13,GNG10,FCER1G,GNG5,SERPINA3,SOD1,PPIA,YWHAZ,SRC,TOR4A,CD36,GNA11,RASGRP2,RAF1,GNB1,CALU,SYK,PCYOX1L,RAP1B,MPIG6B,F2,CYB5R1,PRKCQ,GNAI2,JAK1,SCG3,CSF2,PIK3R3,PRKCB,VTI1B,GNB3,PRKCE,GNGT2,OLA1,SELENOP,GNG3,RAP1A,CLU,AKT2,GNAQ,ENDOD1,RAC2,IL2RA,ALB,ABHD12,P2RY12,CD63,ACTN4,GNB4,SRGN,VAV2,TEX264,PIK3R1,LAMP2,JAK2,PIK3CG,CSK,ABHD6,TAGLN2,IL2,P2RY1,VEGFC,GNG2,GTPBP2,GNG12,LCP2,PRKCA,IGF1,SERPINA1,PTPN11,GNG7,TIMP1,TGFB2 |
| 3.622e-03 | -5.62 | nucleic acid transport | biological process | GO:0050657 | 150 | 60 | 18204 | 5365 |
NXT2,DDX39B,MAGOHB,PHAX,NCBP2,CETN2,RTRAF,EIF4A3,NUP37,SEC13,EIF4E,THOC1,HNRNPA1,MX2,NUP107,THOC2,XPO1,POLDIP3,RFTN2,THOC6,ENY2,PEG10,G3BP2,MAGOH,SRSF7,ZC3H11A,PARP11,NUP42,HNRNPA2B1,FLOT1,THOC3,DHX9,CHTOP,NXT1,SRSF1,NUP35,UPF3B,MRPL18,XPO5,SMG5,NUP62,TNKS,DDX39A,IGF2BP1,XPOT,TOMM20,BICD2,TST,TGFBR2,NUP153,CASC3,NUP50,RBM15B,ALKBH5,FYTTD1,CETN3,FXR2,GLE1,ALYREF,RAN |
| 3.622e-03 | -5.62 | RNA transport | biological process | GO:0050658 | 150 | 60 | 18204 | 5365 |
BICD2,TST,TGFBR2,CASC3,NUP153,NUP50,RBM15B,ALKBH5,FYTTD1,CETN3,FXR2,GLE1,ALYREF,RAN,NUP35,UPF3B,XPO5,MRPL18,SMG5,NUP62,TNKS,DDX39A,IGF2BP1,XPOT,TOMM20,SRSF7,PARP11,ZC3H11A,HNRNPA2B1,NUP42,FLOT1,THOC3,DHX9,CHTOP,NXT1,SRSF1,NXT2,DDX39B,MAGOHB,PHAX,NCBP2,CETN2,RTRAF,EIF4A3,NUP37,SEC13,EIF4E,THOC1,HNRNPA1,MX2,NUP107,THOC2,XPO1,POLDIP3,THOC6,ENY2,RFTN2,G3BP2,PEG10,MAGOH |
| 3.622e-03 | -5.62 | RAB6B (RAB6B, member RAS oncogene family) | protein interactions | 51560 | 103 | 42 | 19454 | 5460 |
RAB6A,SMAD1,DIPK1A,LNX2,HEXIM1,GDI2,RAB4A,ACVR1,RPA2,RAB5A,AKAP1,EGFL7,MAVS,RAB33B,RING1,RABGGTB,HSPA8,FLYWCH2,TMT1A,RPA3,RAB1A,RNF20,ETFA,TGFBR2,GPM6A,BMPR1B,RAB2A,MYC,HAX1,BICD2,VASH1,SPCS3,ARF1,ACOX1,UQCRC2,APEX1,PRNP,MARCHF4,LDHA,OCRL,HNRNPL,RAB1B |
| 3.624e-03 | -5.62 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | GO:0002822 | 194 | 75 | 18204 | 5365 |
XCL1,IL10,IL12B,DUSP22,CD1E,TNF,EP300,TFRC,CLEC7A,RSAD2,SHLD1,TRAF2,KMT5B,IL6,TNFAIP3,HSPA8,LILRB1,IL1B,CD40,FOXP3,IL12A,HFE,CD274,BCL6,HSPD1,IL18,HMGB1,SASH3,CD1D,JUNB,CD226,BATF,CD1A,NECTIN2,AGER,STAT6,FCGR2B,MICB,RC3H2,CLEC6A,STX7,HMCES,IFNB1,JAK2,MAD2L2,EXOSC3,MEF2C,FCGR1A,CD28,B2M,CD80,IL23A,LTA,CD1B,NDFIP1,IL4,CD1C,NLRP3,TRAF6,PRKCQ,SOCS5,IL20RB,TNFRSF1B,TNFSF13,LILRB4,CD81,CYRIB,MIR21,KLRD1,CD4,IFNA2,IL2,CCR2,CCL19,CD46 |
| 3.626e-03 | -5.62 | TERF1 (telomeric repeat binding factor 1) | protein interactions | 7013 | 342 | 119 | 19454 | 5460 |
RPS16,FZR1,SPPL3,KCTD15,CDK9,HCLS1,MRPS9,TNKS,NME2,GTF2A2,NOL12,RPS2,MAP4,GAPDH,KPNA2,TNKS2,MDC1,FKBP8,GNMT,PRDX4,RUSF1,RING1,THG1L,NEFL,TAF2,FBP1,TMSB10,DDX39A,PGM1,LDHA,DNPH1,STUB1,PAFAH1B3,CSNK2B,GANAB,HEXIM2,MSN,MAPRE1,CSK,RPL7A,CEP85,CFL1,KDM1A,GRPEL1,SNCG,PPM1G,IDH3A,NBN,PRKCB,PRDX6,RTN4,CDK1,TOX4,HSP90B1,HEXIM1,UBE2M,ZNF790,SAP30BP,RASGEF1C,CRYM,AFAP1L2,SPTAN1,LYAR,HSP90AB1,THOC2,PPP2CB,PSMB5,S100A8,ZHX1,DDX23,SMAD9,MT1X,RSBN1L,PRDX1,PTPN5,YWHAG,XPO1,PSMA2,LASP1,ZBTB16,HMGN4,BCL7B,HNMT,RPAP3,TUBB4B,NME1,FEN1,SUPT5H,FOXJ3,TNPO2,RPS7,PSMD4,RPL19,APEX1,ENO2,PRMT5,CKB,SENP8,BRCA1,HSP90AA1,H1-1,MDH1,LDHB,RNF40,BAG3,RBM15B,SRM,SKP1,XRCC5,EP300,RNF10,RLIM,TERT,PCLAF,EIF4B,GAMT,AKR1A1,SYK,NEK7 |
| 3.626e-03 | -5.62 | nitric oxide biosynthetic process | biological process | GO:0006809 | 22 | 13 | 18204 | 5365 |
CYB5B,TLR4,ARG2,CYP1B1,MTARC2,ACP5,AKT1,SPR,CAV1,TICAM1,NOS1AP,NQO1,CYB5R3 |
| 3.626e-03 | -5.62 | protein neddylation | biological process | GO:0045116 | 22 | 13 | 18204 | 5365 |
COPS4,NAE1,UBE2F,COPS5,NEDD8,DCUN1D1,COPS2,UBA3,COPS7A,DCUN1D3,UBE2M,DCUN1D5,RNF7 |
| 3.626e-03 | -5.62 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological process | GO:1901028 | 22 | 13 | 18204 | 5365 |
BAK1,ATP5IF1,IER3,GSK3A,SLC25A4,TMEM14A,SLC35F6,SLC25A31,SLC25A5,ACAA2,GCLC,BOK,MUL1 |
| 3.626e-03 | -5.62 | positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological process | GO:1903589 | 22 | 13 | 18204 | 5365 |
MIR146A,MIR10B,APLNR,MIR23A,FGFBP1,MIR21,VEGFA,MIRLET7B,MIR126,MIR503,MIR10A,MIR101-1,MIR132 |
| 3.626e-03 | -5.62 | regulation of CD4-positive, alpha-beta T cell proliferation | biological process | GO:2000561 | 22 | 13 | 18204 | 5365 |
TWSG1,IL2RA,VSIR,PRKCQ,FOXP3,CD274,XCL1,NDFIP1,ARG2,IL2,CD28,TGFBR2,CD81 |
| 3.636e-03 | -5.62 | Znf-RING_euk | interpro domains | IPR027370 | 42 | 21 | 18521 | 5414 |
TRIM5,TRIM45,SHPRH,RNF39,TRIM22,TRAF7,TRIM36,TRIM34,RBCK1,TRIM63,RNF10,RMND5B,TRIM8,RNF222,TRIM46,MAEA,TRIM35,TRIM6,TRIM32,TRIM54,TRIM23 |
| 3.641e-03 | -5.62 | SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5) | protein interactions | 8467 | 387 | 133 | 19454 | 5460 |
DEK,SRC,VIRMA,MACROH2A1,PTEN,ALB,CSNK2B,GSK3A,FGFBP1,EIF4A3,ZNF330,CREB1,CCNF,ATP1A1,CHRAC1,TLR9,AR,DEPDC1B,SMARCA5,HSPA5,SS18,UTP23,MBD3,NUCKS1,SMC4,HMGB1,KDM1A,PRPF4,RPA3,WTAP,HECTD1,HEXIM1,GRM2,LMNA,RPA2,FTH1,ATG16L1,CPSF4,ZBTB2,CDC5L,POLE3,CGAS,TOP1,BRMS1L,MYBL2,KRR1,RCHY1,H2AZ1,BRD3,USP15,KPNA1,SNRNP70,H2AC4,ZMYND11,COPS5,FOXC2,RIGI,SRSF12,PHF1,HUWE1,H3C1,ABCE1,RING1,SEPTIN7,PPP1R12A,NUPR1,NECAP1,IK,CBX3,H2AX,TP53,MTA3,RPL10,ESR2,FBXO22,TUBB,RBBP4,POLR3B,RAN,DLST,NLRP3,BRCA1,MCM3,CPSF2,HNRNPC,MYC,SAP18,STAU1,RAB5A,HSPA8,SF3B1,XRCC5,FOXS1,KLF3,PPARG,MTF1,EED,SRSF1,FBXO32,SIN3A,NCK1,WDR11,CTNNB1,ATG7,DPY30,HMGA1,BAZ1B,IFI16,RAD21,AHCYL1,SSRP1,RUVBL1,SATB1,HMGN4,KRAS,G3BP1,RBBP7,RUVBL2,PPAN,RBPJ,SMARCB1,MTA2,PDHA1,CHMP4C,TUBB4B,EZH2,SAP30,FOXJ3,NCSTN,SOX2,DHX38,RAF1,MAX |
| 3.646e-03 | -5.61 | protein localization to plasma membrane | biological process | GO:0072659 | 197 | 76 | 18204 | 5365 |
TMEM88,PIGW,RAB31,RAMP3,OPTN,FGF13,CAV3,SYS1,TPBG,STXBP1,PSMD10,NHERF1,VAMP2,PIP5K1A,TTC8,SLMAP,TSPAN15,LRP6,EHD3,IKBKB,GOLGA7,EHD4,VAMP5,VAMP3,ATP1B1,EXOC5,ARF6,HYCC2,ARL6IP5,CD81,DLG1,RAB13,GORASP2,TNIK,EMP2,CRB3,SMURF1,F11R,RAP2A,KCNIP3,TSPAN5,JUP,RILPL2,RAP1A,FRMD8,ROCK1,ATP1B3,EHD1,RAB11A,HYCC1,KCNB1,TNF,ADIPOQ,SEC23A,SPTBN1,CACNB2,DPP10,ROCK2,PREPL,NSG1,CACNB3,SCN3B,TESC,S100A10,FCHO2,PLEKHF1,FLOT1,ASB3,ZDHHC4,AKT2,P2RY1,ERRFI1,GOLPH3L,INPP5K,LARGE1,EPHA2 |
| 3.654e-03 | -5.61 | Melanoma | KEGG pathways | hsa05218 | 69 | 35 | 7161 | 2463 |
FGF3,HRAS,FGF13,RB1,CCND1,RAF1,MDM2,IGF1R,PTEN,KRAS,FGF22,CDK6,PIK3R1,MET,AKT1,FGF17,PIK3R2,TP53,FGF16,FGFR1,PIK3R3,FGF1,PIK3CA,FGF7,BAD,FGF10,IGF1,FGF23,AKT2,MAP2K1,CDK4,FGF12,MITF,AKT3,CDKN1A |
| 3.654e-03 | -5.61 | Melanoma | KEGG pathways | ko05218 | 69 | 35 | 7161 | 2463 |
PIK3R2,FGF16,FGF17,TP53,MET,AKT1,PIK3R1,CDK6,FGF22,KRAS,PTEN,MDM2,IGF1R,CCND1,RB1,RAF1,FGF13,FGF3,HRAS,CDKN1A,AKT3,FGF12,CDK4,MITF,AKT2,FGF23,MAP2K1,IGF1,PIK3CA,FGF7,FGF10,BAD,FGF1,FGFR1,PIK3R3 |
| 3.656e-03 | -5.61 | sarcoma | COSMIC cancer mutations | sarcoma | 56 | 26 | 16828 | 4835 |
SS18,EWSR1,SF3B1,RUNX1,SUFU,HRAS,PIK3CA,SMARCB1,DICER1,CTNNB1,RB1,SRSF2,AKT1,PTPN11,IDH2,KRAS,IDH1,FGFR1,PTEN,MET,KIT,TP53,CDKN2C,ETV6,JAK2,FBXW7 |
| 3.660e-03 | -5.61 | monoatomic ion homeostasis | biological process | GO:0050801 | 515 | 180 | 18204 | 5365 |
UBE3A,RMDN3,CCL5,ATP6V0B,STOML2,FTH1,LAMP2,ATP1B3,MYC,BAX,ATP6AP2,TRPC1,HTR2A,CA2,CNNM4,CCL3,VPS33A,KCNJ2,SLC1A3,RNASEK,ATP6V1D,GRM1,MT1X,PRNP,EDNRA,ATP6V1A,FTL,CAV1,IREB2,CAV3,CIB2,KCTD17,TPT1,SNAPIN,FKBP1B,NPTN,MLLT6,KLHL3,PSEN1,ATP2C1,AQP11,SELENON,SLC39A9,ATP1A3,FXN,CIB3,BOK,CALR,CHP1,IL1A,MT3,TF,BAK1,ATP5F1B,VDR,RHAG,HYAL2,SLC1A1,ATP6V1G1,P2RY4,DRD3,MT1E,SMAD4,SLC31A1,PRND,ACO1,FTHL17,CAV2,ATP2B4,SLC4A8,CCR1,PRKCB,LACC1,NDFIP1,FRRS1,GRIA1,RGN,SLC30A7,CNR1,SLC8A1,SOD1,ATP1A2,TRIM24,PICALM,FIS1,ATP1B1,SNX10,CLIC4,SLC39A13,ARF1,CACNB2,SLC39A7,SOD2,NEO1,RHCG,ADORA1,COMT,EXT1,FGFR1,P2RY1,CYB561,SLC4A10,FASLG,TMEM165,ATF4,TM9SF4,SLC25A23,CCL8,COX11,PSEN2,CCL11,ALPL,MAIP1,CYP27B1,FGF23,MT1A,SLC41A1,CHRNA7,HEXB,B2M,TMEM199,ZNHIT1,CCL1,SLC30A5,CCDC47,CA12,FATE1,CCDC22,STIM1,SV2B,PPT1,ATP6V0E1,ISCU,SLC39A10,KCNJ10,VAPB,STC1,CYP11B2,TFRC,SELENOK,TMEM106B,ATP1A1,CYBRD1,TMBIM6,CCL23,CD40,KCNMA1,CXCL12,HFE,CYP4F12,COX19,SMDT1,SLC22A17,S100A8,PML,HSP90B1,DISC1,SLC11A2,GLRX5,NPPC,TASL,SRI,GPR89A,ANKH,CACNB4,BOLA1,MT1M,SLC12A2,BOLA3,PLN,TMEM203,DMPK,CFTR,SLC25A27,CCL19,CCR2,F2,BOLA2B,VPS54,MT2A |
| 3.663e-03 | -5.61 | TTF1 (transcription termination factor 1) | protein interactions | 7270 | 106 | 43 | 19454 | 5460 |
ESR2,SURF6,MDM2,RPL13A,RPL35,LYAR,HNRNPL,RPS10,FGFBP1,RPL37A,PRKRA,TNFRSF1B,KRR1,RPL8,SRP14,RPL10A,H1-1,RPS2,PSMD14,ZNF668,RPL7A,RPL17,UTP23,RPL28,RPL4,DGCR8,NPM3,H1-6,VPS26B,RPL3,RPL23A,SIRT7,HSPD1,RPL31,NLRP2,RPLP0,RBM34,RPA2,SMAD1,RPL15,RPSA,RAF1,RPS14 |
| 3.663e-03 | -5.61 | NLRP3 (NLR family pyrin domain containing 3) | protein interactions | 114548 | 106 | 43 | 19454 | 5460 |
CBX5,UQCRQ,OTUD6A,USP5,SRC,TRIM24,STUB1,HSP90AA1,NLRP3,SPOP,ATP1B3,LAMTOR1,TXNIP,USP14,SNRPB,COPS7A,USP13,SMARCA5,CUL3,PYCARD,HNRNPC,IL1B,MAVS,SQSTM1,CCDC86,STAMBP,LUC7L3,CSNK1A1,FEM1A,NEK7,H1-5,ATG16L1,TOP1,BECN1,HDAC6,RBBP7,USP30,FAF1,HSPD1,DMAP1,CBX3,PGM1,VDR |
| 3.663e-03 | -5.61 | DUSP13B (dual specificity phosphatase 13B) | protein interactions | 51207 | 106 | 43 | 19454 | 5460 |
TXN,RPGRIP1L,CACYBP,SMURF1,TRAF1,DUSP3,SDHB,DLST,LACRT,CNN3,DICER1,AKT1,CALR,PDIA3,PGAM1,PTPN11,CCDC85B,ISCA2,NUP107,PITHD1,SERPINB6,DCTPP1,PRDX4,AHCYL1,HSPD1,CSTB,PDIA6,DCTN3,ACTR1B,GFM1,PRDX6,DCTN4,LMNA,GINS4,ACVR1,FKBP10,HECTD1,ACTR1A,DHRS4,CCS,PPP2R1A,PRDX3,EXOSC8 |
| 3.663e-03 | -5.61 | FOXM1 (forkhead box M1) | protein interactions | 2305 | 106 | 43 | 19454 | 5460 |
RNF8,EZH2,CDK1,CTLA4,USP39,GTF3C4,CCL3,TRMT1L,CDK4,SUMO1,BCL6,FTL,IRF7,SLC31A1,UCHL3,FBXW7,ZC3H11A,EP300,TERT,PML,HSP90AA1,SP1,RIT1,OTUD7B,COPS5,CTNNB1,CREBBP,SMARCA5,MYC,CCNB1,USP5,LRWD1,OS9,FZR1,GSK3A,MYBL2,RB1,UBE2I,ACAT1,CDK6,SMAD3,FBXO31,ZBTB33 |
| 3.669e-03 | -5.61 | H2AC11 (H2A clustered histone 11) | protein interactions | 8969 | 154 | 59 | 19454 | 5460 |
SNRNP70,PPM1B,POLB,AGPAT1,RPS2,HNRNPD,HMGA1,TRA2A,E4F1,COPS5,HDAC6,CAND1,SURF6,RAB11B,SRSF1,KRR1,RCHY1,H2AZ1,H2BC1,RBM34,SART3,MAGEB10,E2F4,RPSA,B3GNT2,SRFBP1,TBK1,H2AX,APOBEC3D,HMGN4,H3C1,NEDD8,TFG,SRSF4,MEPCE,RPL31,H1-1,RPL7A,MYC,ISCA2,THAP7,RPL13A,RPL35,ESR2,VIRMA,RPS3,CCNF,PRKRA,RPL37A,FGFBP1,SDC2,RPLP0,HEXIM1,H2BW1,SSBP2,KDELR2,NPM3,UFL1,MME |
| 3.669e-03 | -5.61 | JAK2 (Janus kinase 2) | protein interactions | 3717 | 154 | 59 | 19454 | 5460 |
CCR5,JAK1,IGF1R,KIT,BACH1,HTR2A,TOP3B,RAF1,BPIFA2,SOCS3,IFNGR1,CTLA4,JOSD1,EZH2,JCHAIN,GHR,PTPN1,ARL11,UBP1,HNRNPL,PPIA,HSP90AB1,PIK3R1,PPP2R5A,YWHAG,HDAC6,CISH,SLC2A1,SHC1,TRAF6,CDKN1B,CBL,CXCR4,HSPA8,GTF2I,LDOC1,IL2RG,IL6ST,TSHR,FGFR1,LEPR,OPTN,NFKBIA,PRMT5,UBASH3B,STAT1,STAT5A,STAT2,CCR2,YES1,SRC,JAK2,CSK,IL2RB,PTPN11,GRB10,PPP1CC,BRCA1,HSP90AA1 |
| 3.682e-03 | -5.60 | Band_7 | pfam domains | PF01145 | 11 | 8 | 17795 | 5224 |
STOML2,FLOT1,ERLIN1,PHB1,ERLIN2,PHB2,STOML3,STOM |
| 3.685e-03 | -5.60 | negative regulation of cell-cell adhesion | biological process | GO:0022408 | 203 | 78 | 18204 | 5365 |
MIR31,NDFIP1,RGCC,MIR222,TNFAIP8L2,IRF1,CCL25,TNR,GPNMB,SOCS5,IL20RB,RUNX1,CCL21,DLG1,LILRB4,MIR146A,EPCAM,CTLA4,PDCD1LG2,MIR30B,MIR21,IFNA2,CD9,IL2,SFTPD,MIR221,PLA2G5,CCL28,RC3H2,MIR125A,MIR181C,IFNB1,C1QTNF1,JAK2,IL2RA,TNFRSF14,MAD2L2,LGALS3,UBASH3B,NF2,MIRLET7G,VEGFA,CBFB,CD80,MIR141,ARG2,SWAP70,YTHDF2,LILRB1,CD274,HFE,FOXP3,BCL6,AKT1,CXCL12,PTPN22,PRDX2,SPINT2,HMGB1,PLG,PPARA,ADTRP,PELI1,FGL2,PRNP,KLF4,BTN2A2,DUSP22,IL10,XCL1,DUSP3,IDO1,VSIR,SDC4,ADIPOQ,TWSG1,CD86,CDSN |
| 3.687e-03 | -5.60 | FCERI mediated MAPK activation | REACTOME pathways | R-HSA-2871796 | 265 | 104 | 10285 | 3229 |
PSMD12,JAK1,MAPK10,FGF7,CSF2,RAP1A,SHC3,SPRED2,IL2RA,PSMB9,HBEGF,PSMD6,PSME2,FGF3,DUSP10,NEFL,GRAP2,MAP3K11,PSMC4,VAV2,FOS,PSMB5,PSMA3,PSMB1,JAK2,PSMB7,PSMD3,CSK,BRAP,DLG4,PSMB6,PSMA2,PSMB10,PSMB11,JUN,FGFR1,PSMC5,IL2,PSMA4,FGF17,PSMD7,PSME1,ANGPT1,PPP5C,SPTBN1,PPP2R1A,UBB,LCP2,PSMD14,PSMC1,CUL3,VWF,CAMK2G,LAMTOR3,IL2RB,FGF16,PEA15,PSMA6,PSMD1,PSMB2,IL5,PPP2CB,KIT,LAMTOR2,HRAS,DUSP1,SEM1,PSMB4,PAK2,SHC1,RASGRP3,PHB1,PSMD4,SPRED1,RPS27A,IL3,PSMA1,PSMC3,FGF1,PPP2R5A,DUSP6,YWHAB,IL2RG,PEBP1,PSMB3,PPP2R5E,SPTAN1,PSMA5,FGF23,PAQR3,MET,FGF10,DUSP9,SRC,FRS3,PSMD10,RAF1,WDR83,SYK,FGF22,UBA52,KRAS,MAP2K1,RAP1B |
| 3.691e-03 | -5.60 | response to amino acid | biological process | GO:0043200 | 127 | 52 | 18204 | 5365 |
LAMTOR2,TUBA1A,STAMBPL1,EIF2S1,MIR545,GLRA2,MIR455,RRAGB,BCL2L1,SLC38A9,UFL1,CAPN2,NTRK2,MYD88,CASTOR2,MIR421,MIR342,SESN2,AMIGO1,XBP1,KLHL22,NQO1,LAMTOR1,CDO1,CPEB1,CUL3,GRIA1,CDKN1B,TAF9,COL1A2,HPCA,SESN3,HNRNPD,SLC1A2,IGF1R,PCNA,MIR95,GLRA1,EP300,RRAGA,F7,KCNB1,PIK3CA,TNF,TOMM70,SH3BP4,AIFM1,TMBIM6,LAMTOR3,GCLC,COL3A1,SST |
| 3.691e-03 | -5.60 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | GO:0002824 | 127 | 52 | 18204 | 5365 |
SASH3,CD1D,IL18,CD274,IL12A,HFE,FOXP3,HSPD1,CD40,IL1B,HSPA8,MICB,STAT6,NECTIN2,CD1A,CD226,EP300,TNF,CD1E,IL12B,XCL1,TRAF2,RSAD2,CLEC7A,SHLD1,IL6,KMT5B,TFRC,TNFSF13,TRAF6,NLRP3,PRKCQ,CD1B,CD1C,IL4,CCR2,IL2,CD4,MIR21,CYRIB,CD81,MAD2L2,HMCES,JAK2,STX7,CLEC6A,LTA,IL23A,B2M,CD28,FCGR1A,EXOSC3 |
| 3.694e-03 | -5.60 | SPSB1 (splA/ryanodine receptor domain and SOCS box containing 1) | protein interactions | 80176 | 33 | 17 | 19454 | 5460 |
TGFBR2,TRIM63,KRAS,SPPL3,KDM1A,HNRNPL,SPSB1,TTC1,DDX4,RNF7,ADPRH,MET,HSP90AA1,TP53,PRMT6,ELOC,SUV39H1 |
| 3.694e-03 | -5.60 | DNAJB7 (DnaJ heat shock protein family (Hsp40) member B7) | protein interactions | 150353 | 33 | 17 | 19454 | 5460 |
PBDC1,BAG2,PYM1,GRPEL1,CMAS,AHCYL1,FKBP8,RPL4,RPL26,ASPM,SEC22B,IPO8,RPL7A,DNAJC7,RPLP0,RPL18,NUPR1 |
| 3.694e-03 | -5.60 | USP38 (ubiquitin specific peptidase 38) | protein interactions | 84640 | 33 | 17 | 19454 | 5460 |
RPL7,FBXW7,SEM1,H3C1,LDHA,KDM1A,VIRMA,USP38,RPS27A,MCM6,RPS12,CKB,VAV2,HSPB1,BIRC5,H1-3,DDX39A |
| 3.694e-03 | -5.60 | DLX6 (distal-less homeobox 6) | protein interactions | 1750 | 33 | 17 | 19454 | 5460 |
IP6K1,TTC9C,COIL,CBX5,RNASEH2C,PARP2,HAPSTR1,SEMG2,DCAF5,LACRT,CHMP1A,GNB1L,PAXX,HSP90AA1,RBPJ,ATG7,CFTR |
| 3.694e-03 | -5.60 | ZCCHC12 (zinc finger CCHC-type containing 12) | protein interactions | 170261 | 33 | 17 | 19454 | 5460 |
CREBBP,SUMO1,MX1,RNF40,SMAD1,ABHD5,FATE1,SPOP,TFCP2,PNMA2,RUSF1,PNMA1,APPBP2,UBE2I,TNF,SUMO2,SUMO3 |
| 3.694e-03 | -5.60 | SLC38A9 (solute carrier family 38 member 9) | protein interactions | 153129 | 33 | 17 | 19454 | 5460 |
LAMTOR3,LGALS3,RRAGB,HNRNPL,APEX1,RAB9A,LGALS8,LAMTOR1,RAB5C,LAMTOR2,SLC38A7,GPR17,RAB2A,LAMP2,RRAGA,DDX39A,LAMP3 |
| 3.694e-03 | -5.60 | BDKRB1 (bradykinin receptor B1) | protein interactions | 623 | 33 | 17 | 19454 | 5460 |
HILPDA,UQCRC1,OAZ2,TP53,TRAM1L1,GNAQ,TMEM42,SLC25A28,RTN4,ZNF22,TMX2,SLC6A8,MDC1,RETREG1,GABBR1,NF2,NDFIP1 |
| 3.698e-03 | -5.60 | ROR1 (receptor tyrosine kinase like orphan receptor 1) | protein interactions | 4919 | 109 | 44 | 19454 | 5460 |
EPHA2,HSP90AA1,SERPINH1,EPS8,TBC1D1,GORASP2,VIRMA,SEC63,EIF2S2,SYT2,MACROH2A1,VAPB,JUP,PICALM,TOMM22,DUSP18,DUSP14,USP6NL,NOTCH2,CNP,PIK3R2,PPM1B,PIK3R1,STOML2,EIF2S1,TOP1,CDK9,CAV1,SRPRA,HRAS,MRTO4,UBE2N,GJA1,PWP2,SMARCB1,TBC1D4,KRAS,DUSP21,ARF4,SSRP1,DUSP19,SFXN1,TRIM21,DHX9 |
| 3.698e-03 | -5.60 | SLC9A1 (solute carrier family 9 member A1) | protein interactions | 6548 | 109 | 44 | 19454 | 5460 |
LMAN1,DIRAS3,OPRL1,ARF6,CX3CL1,RHOH,LHFPL4,HSD17B11,FUT1,RAC2,HRAS,RAB35,YWHAB,SLC20A1,RHOG,CCR6,LAMP3,MAP3K14,MDFI,KRAS,TMT1A,SEMA7A,RPN1,ROCK1,APEX1,CHP1,RHOJ,IL2RA,SEC61B,ENO1,HSP90AA1,CA2,RHOB,RAB2A,AKT1,STX7,LPAR1,TESC,CDC42,SEC62,RND2,FAXC,OTULINL,ST7 |
| 3.698e-03 | -5.60 | TMEM109 (transmembrane protein 109) | protein interactions | 79073 | 109 | 44 | 19454 | 5460 |
KRAS,IMMP2L,TMT1A,DISC1,TFCP2,RPN1,EZH2,CCDC47,GDE1,SOX2,PHB1,RAC2,HSD17B11,RHOG,AQP2,PDZK1IP1,ADIPOR2,RAB5C,LAMP3,TMEM106B,RPA3,DERL1,SYVN1,FGFR1,METTL14,STOM,SSR1,LMNA,RPA2,CRYAB,ST7,SEC62,CDC42,FBXO22,MGST3,ESR2,CYB5R3,LMBR1L,CCNF,SEC61B,LMNB1,FAS,RAB2A,TOMM40 |
| 3.700e-03 | -5.60 | leukocyte differentiation | biological process | GO:0002521 | 425 | 151 | 18204 | 5365 |
DHRS7B,TLR2,TRAF6,NDP,CEBPG,KIT,LTBR,NHEJ1,CCL19,IL2,IRF4,TGFBR2,VPS54,DNAJB9,STAT5A,RHOH,FOS,IL15RA,FOSL2,SYVN1,TOB2,HDAC5,RAG1,IRF8,GPR89A,SLC25A5,TOP2B,CEBPE,SYK,CD1D,HMGB1,PTPN22,BCL6,EPHA2,PIR,RABL3,FAM20C,IFNA13,CCR6,ITGB8,STAT6,PKNOX1,FCGR2B,CCR7,RPL22,STK11,BATF,LBR,NOTCH2,EP300,TNF,LMBR1L,UCP2,PIK3R3,CLPB,IL10,RBPJ,CTNNB1,TESPA1,TUSC2,BAK1,CTSK,TF,TFRC,TOX,CMTM7,JAGN1,IL2RG,IFNK,TPD52,PIK3R1,RUNX1,CD3G,PIK3R2,TCTA,PSMB11,MYD88,IRF1,IL4,JAK1,IFI16,LIPA,PPARG,PDP2,IFNA2,CD4,PTGER4,PSEN1,CD81,OSTM1,PDE1B,TYROBP,FBXO7,SOCS3,SRP54,IL15,IFNB1,EGR1,WNT10B,RC3H2,KDELR1,BAP1,CBFB,CD28,B2M,VEGFA,ITK,ST3GAL1,IL7,IREB2,EZH2,JUNB,CD79B,NKAP,SASH3,CD83,LARGE1,FOXP3,LILRB1,CSF2,DCLRE1C,NFIL3,TNFSF8,CDK6,TLR4,CD40LG,LRRC8A,LEP,PAFAH1B1,FOXP1,ITM2A,GLO1,TP53,IL12B,IFNG,SNX10,FCER1G,BAX,MITF,TRAF3IP2,IL6,RSAD2,CREB1,SFRP1,AZI2,IL21,LEPR,MMP9,SLC39A7,CDC42,IFNA10 |
| 3.705e-03 | -5.60 | ARF | smart domains | SM00177 | 43 | 20 | 9717 | 2575 |
ARF4,RAB18,RAB1B,ARF6,ARL4D,ARL5B,RAB37,ARL10,RAB13,RAB1A,ARL4A,RAB8B,ARF1,ARL15,TRIM23,ARL6,ARL11,RAB4A,RAB35,SAR1B |
| 3.707e-03 | -5.60 | MTA2 (metastasis associated 1 family member 2) | protein interactions | 9219 | 413 | 141 | 19454 | 5460 |
CUL3,HNRNPC,MYC,CPSF2,SMARCE1,BTF3,BRCA1,FAM219A,HSP90AA1,DLST,RAN,PHF12,BAD,PRMT5,FAM43A,ZMYM2,RBBP4,ACTB,ESR2,MAD2L1,WDR77,ACTL6A,EMC9,NACC2,TCF19,EP300,HSPA8,GPHN,HDAC5,STAU1,EEF1G,UFL1,SAP18,DPY30,MARCHF5,HMGA1,CTNNB1,DDRGK1,DENND6B,HNRNPD,SIN3A,CCDC71,EED,SUMO2,TRIM35,HMG20A,E2F4,RAF1,TOP3B,NAA15,ZNF263,CSNK1E,GTF2E2,SAP30,SOX2,PDHA1,EZH2,STMN2,MOB3C,POLR2C,MTA2,SMARCB1,PABPC1,TOP2B,SLC25A5,RTCB,RUVBL1,SATB1,ASF1A,ROCK2,RBBP7,ZBED1,G3BP1,EMC8,ZBTB16,SSRP1,RAD21,SUB1,SMARCA5,TUFM,RUNX1,CFL1,UBE2H,SMAD2,CCNF,MACROH2A1,CSNK2B,ADRM1,TMOD3,VIRMA,RPP25,EEF1E1,ATG16L1,MED30,CD2AP,MRPS34,RPA2,HEXIM1,SIRT7,BANF1,RPA3,BAP1,RNF113A,NUCKS1,SMC4,GTF2I,KDM1A,LSM8,MBD3,CSNK2A1,SNRNP70,USP15,MAP4,KPNA1,SMAD3,EEF1B2,H2AZ1,GATAD1,MYBL2,BRMS1L,TOP1,TSC22D3,SHPRH,FZR1,ZBTB2,MRPS23,TP53,MTA3,ZMYM3,ACTR1A,H2AX,CCDC69,HAPSTR1,KPNA2,CDK2AP2,TSSC4,H3C1,PSMA5,RIGI,PHF1,MEPCE |
| 3.714e-03 | -5.60 | CCNB2 (cyclin B2) | protein interactions | 9133 | 60 | 27 | 19454 | 5460 |
VAPB,CDK1,RPA2,GHITM,CKS2,CKS1B,CDKN1A,CDK7,KRAS,TGFBR2,SKP1,RNASEH2C,RPA3,TMT1A,CDK5,CIRBP,CDKN1B,CRHBP,GMPPB,CCNB1,NDC80,FAM163B,XPO1,CDK17,CREB1,LMBR1L,HSD17B11 |
| 3.714e-03 | -5.60 | COX1 (cytochrome c oxidase subunit I) | protein interactions | 4512 | 60 | 27 | 19454 | 5460 |
COX4I1,KCNMB1,COX7A1,DLG4,RETREG3,EDNRA,COX14,APLNR,UQCRQ,OPRM1,GPR17,COX5A,MRPL18,NDUFB8,TSPAN15,HSPB2,VIPR1,TACR1,SLC15A1,GRPR,EMC1,PRDX4,COMTD1,COX4I2,CDC42,COX7B2,P2RY12 |
| 3.714e-03 | -5.60 | MASTL (microtubule associated serine/threonine kinase like) | protein interactions | 84930 | 60 | 27 | 19454 | 5460 |
CUL3,CEP85,AGR2,PTTG1,UBN1,EIF4A3,CCNF,DERL2,RPL35,SNRNP40,SPPL3,EGLN3,PLEKHA8,CDC42,PPP2R1A,RPA2,LMNA,CBX3,ZNF574,TCOF1,PML,TMEM263,RPA3,SRSF7,FBXW7,IMMP2L,FASTKD5 |
| 3.714e-03 | -5.60 | MTFR1L (mitochondrial fission regulator 1 like) | protein interactions | 56181 | 60 | 27 | 19454 | 5460 |
AKAP1,EFHC1,RMDN3,ARMC1,ESR2,PFDN1,TACR3,EGLN3,PHB2,HSCB,KCTD3,MRPL12,XPO1,CLEC2B,MTCH2,CUL3,SLC25A46,INPP5E,CNOT2,HAUS2,HTRA2,PFDN2,FIS1,PFDN4,YWHAZ,GHITM,FAS |
| 3.714e-03 | -5.60 | UBE2Q1 (ubiquitin conjugating enzyme E2 Q1) | protein interactions | 55585 | 60 | 27 | 19454 | 5460 |
TCEAL1,PRNP,MDM2,EGLN3,HSP90AB1,CCNF,STUB1,COX4I1,PSMC5,SYT2,PSMD14,GPR17,SRPRB,PSMC1,TACR3,RNF26,DDX46,FHL3,LMNA,RNF7,LARP4B,IRF2BPL,PSMC3,PSMC4,TP53,ARFGEF1,HCST |
| 3.714e-03 | -5.60 | SLC5A3 (solute carrier family 5 member 3) | protein interactions | 6526 | 60 | 27 | 19454 | 5460 |
RHOB,DPP4,LAMP2,RAB2A,GPR17,OPRM1,LAMP3,DNAJC5,ARF6,APLNR,CAV1,VIRMA,RAB35,HRAS,EDNRA,GPR173,P2RY12,AQP3,CRELD1,OR4N2,LPAR6,DIO3,KRAS,LPAR1,STX7,HS2ST1,SLC5A6 |
| 3.714e-03 | -5.60 | IER3IP1 (immediate early response 3 interacting protein 1) | protein interactions | 51124 | 60 | 27 | 19454 | 5460 |
CYSTM1,TMEM237,VIRMA,AIG1,CDIPT,PLP1,TMEM14A,ELOVL4,CSNK2B,FCER1G,TM4SF18,MOV10,SCN3B,CERS2,GJB1,RER1,RGS2,PEBP1,TMX2,JAGN1,GNG5,ACACA,FAM3C,TMEM14B,GOSR2,YIPF4,YIPF5 |
| 3.714e-03 | -5.60 | FMN2 (formin 2) | protein interactions | 56776 | 60 | 27 | 19454 | 5460 |
CDC42,IMP3,CAPN2,AVPR1B,PTP4A2,FLOT1,KRAS,SLC31A1,TGFBR2,YWHAG,LAMP3,YWHAH,RAB2A,LAMP2,SFN,RHOG,LAMTOR1,RHOB,TRIM24,CFAP298,RAB35,SMURF1,DIRAS3,CAV1,CEP19,ARF6,ACTB |
| 3.716e-03 | -5.60 | ATP1B1 (ATPase Na+/K+ transporting subunit beta 1) | protein interactions | 481 | 148 | 57 | 19454 | 5460 |
TRAF6,AGR2,SLITRK5,ATP5MG,MRPS35,ILVBL,LMAN1,PRNP,RAB1B,RAC2,PHB1,NDUFA12,NDUFS3,PDHA1,EZH2,MTCH2,NDUFA2,RAF1,ATP5PB,VDAC1,HSD17B10,PSME1,HNRNPA2B1,BACE1,RAB1A,ATP1A1,RHOB,BRCA1,ATP1A3,RPL26,TOMM40,CTSD,ACO2,COX6B1,VIRMA,DDAH2,PDCD5,LRIF1,UQCRQ,CPT2,SC5D,PSMD6,RHOJ,EIF4H,ADGRL3,ACAT1,CCNF,CYC1,TM9SF1,ACAA2,RPA2,HSPA5,PMAIP1,DLAT,RTN4,HADHA,RPA3 |
| 3.717e-03 | -5.59 | 3-hydroxyacyl-CoA dehydratase activity | molecular function | GO:0018812 | 7 | 6 | 18094 | 5411 |
HACD2,HACD1,HACD3,HADHA,EHHADH,HACD4 |
| 3.717e-03 | -5.59 | TPR domain binding | molecular function | GO:0030911 | 7 | 6 | 18094 | 5411 |
RAB8B,SRP72,PDE2A,HSP90AA1,HSP90AB1,STUB1 |
| 3.717e-03 | -5.59 | nitric-oxide synthase regulator activity | molecular function | GO:0030235 | 7 | 6 | 18094 | 5411 |
HSP90AA1,AKT1,ATP2B4,NOS1AP,HSP90AB1,DYNLL1 |
| 3.726e-03 | -5.59 | VPS50 (VPS50 subunit of EARP/GARPII complex) | protein interactions | 55610 | 112 | 45 | 19454 | 5460 |
STX6,HMG20A,NUF2,RPRD1A,LAMP2,ATG9A,INSYN1,EXOC1,CTNNBL1,FANCG,TFPT,TFRC,CRABP2,RAB4A,SNAP29,MAX,PPIL3,ACTR1A,MATR3,FBXO22,APLNR,VIRMA,CD79B,PHF21A,LAMTOR1,STK24,CCHCR1,CSK,GPR17,RAB11A,MCM4,KDM1A,NPTN,HSCB,OIP5,STX7,SLC39A9,RPA3,RAB9A,HSP90B1,GOLGA5,GIT2,SCLT1,VPS54,ATG16L1 |
| 3.726e-03 | -5.59 | PTPRU (protein tyrosine phosphatase receptor type U) | protein interactions | 10076 | 112 | 45 | 19454 | 5460 |
CTLA4,CIBAR1,AAMP,GNAI3,NCR3,MACO1,PI15,TP53,CBLN4,KIT,CSE1L,PSMD12,CA10,PDIA6,ARHGAP5,PDIA3,CALR,SCGB1D1,XPO1,CTNNB1,DNAJB9,FIBIN,NRSN1,PPFIA3,LEMD3,FUT8,TMEM106A,ST7,CLEC12B,GPIHBP1,ST8SIA4,UNC45A,HFE,SDF2L1,DNAJC10,NXPH3,PSMD1,APEX1,PRRC2A,VIRMA,RPL10,GNAI2,CTNNA1,GNAO1,GANAB |
| 3.726e-03 | -5.59 | MPP1 (MAGUK p55 scaffold protein 1) | protein interactions | 4354 | 112 | 45 | 19454 | 5460 |
ATRAID,GPRASP3,MAGOHB,PRDX2,FBXO22,NR1H2,STUB1,OPTN,DLG4,AP2M1,PTEN,RPA2,EFHD1,SLC35E1,FXR2,HSCB,STK38,STAU1,SKP1,RPA3,EEIG2,MRPS26,ID1,HNRNPD,PRDX1,LAMP2,DERL2,SRSF10,DKC1,DIRAS3,STK3,HRAS,RPRM,XXYLT1,KLHL12,SYNGR3,PAQR8,TP53,G3BP1,KRAS,TRIM63,APH1A,ZNF287,SMN1,GADD45A |
| 3.726e-03 | -5.59 | MNAT1 (MNAT1 component of CDK activating kinase) | protein interactions | 4331 | 112 | 45 | 19454 | 5460 |
SP1,BRCA1,BEX3,CUL3,CCNB1,MYC,LRIF1,SNRNP40,GTF2H2,CDC7,ZNF174,GTF2H5,RNF7,HPS6,RPA2,CDK7,CCNH,GTF2H4,DNAAF9,RNF41,HMGB1,TRIM5,RPA3,FOXP1,POU5F1,TRIM34,GMPPB,USP2,ERCC3,CETN2,EGLN3,RB1,NKX3-1,DMAP1,CDK8,HOXB1,GTF2E2,EEF1A1,SUPT5H,TP53,PI15,MAGEC2,SSRP1,TRIM26,TRIM21 |
| 3.726e-03 | -5.59 | MCAT (malonyl-CoA-acyl carrier protein transacylase) | protein interactions | 27349 | 112 | 45 | 19454 | 5460 |
HNRNPDL,MRPS7,MRPS18C,MRPS17,ITGAV,MRPS33,EP300,SPCS2,MRPS11,MRPS18B,EWSR1,RBM3,EIF1AD,RPA3,PREPL,NGRN,MRPL51,ZNF574,MRPS34,RBMS2,SHMT1,RAF1,RPL10,MRPS23,TFEB,DBT,MALSU1,SPTAN1,MRPS21,MRPS28,PRSS8,PRR3,ALYREF,MRPS9,PTPN1,RIT1,MRPS26,MRPS25,NOA1,CIRBP,MRPS16,USP14,HNRNPA1,MRPS35,MYC |
| 3.726e-03 | -5.59 | NIPAL1 (NIPA like domain containing 1) | protein interactions | 152519 | 112 | 45 | 19454 | 5460 |
MED29,FITM2,FAR2,FAM241A,SPPL3,TLCD4,SRPRA,PTPN1,MCL1,MFSD5,PTRH2,YIPF3,SLC29A1,B4GALT7,PGAP4,GALNT2,FKRP,ATP2B4,MAN1A2,NAPA,TMEM38B,SLC30A5,TLCD2,SEC63,SCAMP2,NIPA2,VAMP3,SELENOT,SLC1A1,GPR89A,GOLGA5,LMBRD2,VAPB,FAM3C,FUT8,GOSR2,SLC19A2,HACD2,ST7,SEC62,RER1,CXCR4,ATP2C1,CCDC126,RAB5A |
| 3.726e-03 | -5.59 | PPIH (peptidylprolyl isomerase H) | protein interactions | 10465 | 112 | 45 | 19454 | 5460 |
NIF3L1,SNRNP70,LSM6,HNRNPD,USP15,MYC,CUL3,PRPF31,SNRPB,ST13,DDRGK1,FZR1,RPS10,TOP1,PRPF18,RBM42,ESR2,PTPN1,RPL32,ALYREF,SNRPD2,TRIM24,SKA3,LSM2,RPL26L1,NUPR1,SART3,SF3A1,RAF1,LNX2,SOX2,CD2BP2,B9D2,HUWE1,LSM4,PPWD1,MEPCE,OLA1,LSM8,SSRP1,BAP1,METTL18,PRPF4,BAG2,PPIH |
| 3.729e-03 | -5.59 | ARL8B (ADP ribosylation factor like GTPase 8B) | protein interactions | 55207 | 194 | 72 | 19454 | 5460 |
STX7,PIP4P1,CLDND1,GRPR,MAVS,ARPC2,PMAIP1,RAB29,FOS,DUSP9,RPA3,LEMD3,KLC2,METTL14,WWP1,FOXS1,RPA2,KLRD1,CDC42,SEC22B,RHOJ,ARMC6,TUBB,RAB14,CYB5R3,INPP5K,VDAC2,MAPRE1,MYO6,YWHAZ,RHOB,LAMTOR1,GORASP2,USP14,RAB2A,DUSP19,SRPRB,ETFA,G3BP1,TNFSF8,LRRN4CL,DHX9,OAZ3,TMEM14B,TBC1D4,EZH2,STIM1,SPG21,LBR,DDX39A,CMPK1,RAF1,VAMP7,CCAR2,CGAS,CPLX3,RAC2,ATP6V1A,GATAD1,RBM5,RPL9,YWHAB,TRAPPC4,VPS4A,AGR2,RHOG,YWHAG,YWHAH,LAMP3,TSPAN10,LAMTOR2,CIDEB |
| 3.729e-03 | -5.59 | UHRF1 (ubiquitin like with PHD and ring finger domains 1) | protein interactions | 29128 | 194 | 72 | 19454 | 5460 |
PRKCB,PML,XRCC5,HELLS,STAU1,FBXW7,NUCKS1,KDM1A,UBE2D3,PCLAF,WRAP53,PPP2R5E,MACROH2A1,PRMT5,ZNF330,PARP2,CCNF,RPL10,APEX1,TCEAL1,USP14,AR,MCM3,CUL3,AKT1,SMARCA5,MYC,RIT1,SETD7,HSP90AA1,BRCA1,LMNB1,CCDC22,FBXW11,PCNA,SSRP1,MSH6,PTGES3,H3C1,KDM4B,LASP1,KRAS,SAP30,JUN,H2AX,E2F4,TP53,RAF1,ATP5PB,ZNF263,NUPR1,EZH2,CBX3,RB1,UBE2N,ALYREF,EEF1AKMT3,CD274,H2AZ1,TMCC2,PSD2,RPL35A,FZR1,SUV39H1,MPG,ATG7,HMGA1,UBXN6,BRD3,AHSA1,KPNA1,UBE2D1 |
| 3.735e-03 | -5.59 | pancreas-other-dysplasia-in_situ_neoplasm | COSMIC cancer mutations | pancreas-other-dysplasia-in_situ_neoplasm | 48 | 23 | 16828 | 4835 |
KRAS,IDH1,SMAD4,TP53,KIT,MET,FBXW7,JAK2,FGFR1,PTEN,KLF4,HRAS,STK11,GNAQ,GNA11,RB1,CTNNB1,IDH2,PTPN11,AKT1,PIK3CA,EZH2,SMARCB1 |
| 3.735e-03 | -5.59 | dysplasia-in_situ_neoplasm | COSMIC cancer mutations | dysplasia-in_situ_neoplasm | 48 | 23 | 16828 | 4835 |
EZH2,SMARCB1,PTEN,PIK3CA,FGFR1,FBXW7,IDH2,AKT1,PTPN11,JAK2,TP53,CTNNB1,KIT,GNA11,MET,RB1,SMAD4,GNAQ,STK11,IDH1,KLF4,KRAS,HRAS |
| 3.745e-03 | -5.59 | CXCL9 (C-X-C motif chemokine ligand 9) | protein interactions | 4283 | 77 | 33 | 19454 | 5460 |
SSMEM1,CXCL14,AMIGO1,TSPAN18,CXCL11,FNDC9,SYNE4,TMEM237,CXCR3,DPP4,TMED5,CXCL12,PTPN5,CCL5,CCL11,RHCG,FCGR2A,FBXO7,CCL28,TMEM106C,TM4SF18,CLEC7A,BSCL2,TNFSF8,GJB1,CCL2,CXCL10,CCR3,STRBP,XCL1,TMEM31,SFTPC,CCL21 |
| 3.745e-03 | -5.59 | ESPL1 (extra spindle pole bodies like 1, separase) | protein interactions | 9700 | 77 | 33 | 19454 | 5460 |
CUL3,CCNB1,PPP2R5A,MOV10,CDC16,XPO1,FBXO7,CAMSAP2,HNRNPD,HAX1,PTTG1,DNAJC7,PPP2CB,ACKR3,LMBR1L,GFOD1,VIRMA,CCT7,CDK9,TOP3B,PPP2R1A,DNAJC2,CDK1,CKS2,TRIM36,RPA3,DVL2,BAG2,HSPA8,STAU1,TRIM63,KRAS,FKBP8 |
| 3.745e-03 | -5.59 | GPR37 (G protein-coupled receptor 37) | protein interactions | 2861 | 77 | 33 | 19454 | 5460 |
SDCBP,JKAMP,HSP90B1,GHITM,PACRG,TMEM231,RRM1,GABARAPL2,GABBR1,CNTN1,ADRB2,FKBP8,POLD2,TMED1,ADRA1A,SYVN1,PICK1,HSPA8,SPATA2L,YIF1A,CCT2,FAM219A,GPR17,SLC41A3,CCNQ,FBXO22,TCP1,GPR37,VIRMA,STUB1,G6PC3,FA2H,KRT8 |
| 3.748e-03 | -5.59 | CCR5 (C-C motif chemokine receptor 5) | protein interactions | 1234 | 49 | 23 | 19454 | 5460 |
CCL11,CCL5,CCR2,ARL6IP5,STAT1,STAT5A,GNAI2,JAK2,DNM2,GNAO1,CD4,GNAQ,GNAI3,CCL3,TPST1,PSMA5,CCL2,SLC20A2,PIK3R2,CCL8,CCR5,CXCR4,JAK1 |
| 3.748e-03 | -5.59 | NAPRT (nicotinate phosphoribosyltransferase) | protein interactions | 93100 | 49 | 23 | 19454 | 5460 |
APEX1,PPP5C,IDE,ARMC1,IGBP1,DHRS11,NIF3L1,ARMT1,SEC13,USP14,HNRNPK,TOLLIP,PAFAH1B2,GRAMD2B,TCEA1,HSPA8,TRMT112,TXNRD1,TNRC6C,TOP3B,ST7,MAP2K3,EEF1A1 |
| 3.748e-03 | -5.59 | ZFYVE26 (zinc finger FYVE-type containing 26) | protein interactions | 23503 | 49 | 23 | 19454 | 5460 |
RAB9A,PNMA1,VIRMA,TRAF1,NPTN,SPPL3,PLEKHF2,TTC23,CFTR,GPRASP2,HNRNPC,OPRM1,PNMA5,AP5S1,MDFI,LAMP2,TOP3B,TFIP11,FIS1,SSX2IP,PPT1,LAMTOR1,PPP1R16A |
| 3.748e-03 | -5.59 | COX6A1 (cytochrome c oxidase subunit 6A1) | protein interactions | 1337 | 49 | 23 | 19454 | 5460 |
SPPL3,UQCRQ,RMND1,SLC25A12,COQ8A,COX4I1,NRP1,MICB,COX6B1,NDUFV2,NME4,CHCHD2,SLC25A51,NDUFA4,COX6C,LXN,NDUFS3,AQP3,NDUFA5,TOP3B,UQCRC1,DHRS4,COX4I2 |
| 3.749e-03 | -5.59 | NFKB2 (nuclear factor kappa B subunit 2) | protein interactions | 4791 | 115 | 46 | 19454 | 5460 |
SKP1,FBXW7,GTF2I,MTDH,COMMD2,BIRC2,HDAC5,PML,RFXANK,ATG16L1,ESR2,SEC61A1,GSK3A,NFKBIA,NFKBIB,CCNF,POLR1B,SP1,ATP1A1,FBXW11,EPS8,CUL3,MYC,TNFAIP3,RPS13,KPNA2,RBBP7,NKRF,TIMM8A,MAP1LC3B,TP53,TOP3B,TBK1,VDR,FBP1,TSC22D3,IL10,TSG101,EEF1AKMT3,IKBKB,MAP3K14,XPO1,RPL6,USP2,MOV10,NFKB1 |
| 3.749e-03 | -5.59 | GPKOW (G-patch domain and KOW motifs) | protein interactions | 27238 | 115 | 46 | 19454 | 5460 |
TRIM27,PTEN,FAM177A1,JUNB,MED17,GSTM5,FBXO7,BAG3,SYCE3,HNRNPC,PIM2,UBE2H,RIT1,RBBP8,TRIM23,NUP50,TCEA1,RPA3,ARMCX1,PRPF4,PML,CNKSR3,WDR83,WDR77,SPDYE4,DDIT4L,ATG16L1,HEXIM1,KLC2,LMNA,RPA2,FBXO32,HDAC6,XPO1,GMPPA,PICK1,TCEA2,PHF1,DHX16,KRAS,TRAF2,RAF1,DHX38,E2F4,POLR2G,CBX3 |
| 3.749e-03 | -5.59 | CTPS2 (CTP synthase 2) | protein interactions | 56474 | 115 | 46 | 19454 | 5460 |
SLC2A1,YWHAB,TNFAIP6,FAM174A,ICAM2,XPO1,SUV39H1,RHOH,SPTAN1,RAMP3,MRPS23,MTMR2,SPG21,HNRNPF,CDK20,RNASEH2C,EHD4,CHST10,FAF1,RPL23A,LRRN4CL,PSMD14,TYROBP,UBE2H,SUGP1,SFN,CUL3,DHPS,MCM3,SNX3,TSN,APLNR,LMBR1L,RAB28,DLST,RPL37A,APOBEC3C,RPA2,FGFR1,RRAGA,EHD1,GTF2I,CYFIP2,RPA3,VIPR1,DDX5 |
| 3.753e-03 | -5.59 | positive regulation of epithelial cell proliferation | biological process | GO:0050679 | 218 | 83 | 18204 | 5365 |
CDC42,CCL24,MIR135B,EGFL7,LACRT,FGF10,CTNNB1,MYC,WNT2,TNFAIP3,SFRP1,MIR126,MIR101-1,IL10,RBPJ,HMX2,NOTCH2,CCR3,IGF1,POLD4,TNF,CCL5,HRAS,MIR23A,PROX1,ZNF304,EMC10,VEGFC,APLNR,MIR10A,MTA3,CCL11,SEMA5A,NME2,NOG,HDAC6,CDH13,AKT3,MIR132,AKT1,CXCL12,SCG2,APLN,OSR2,FGFR1,MIR495,TNFSF12,HMGB1,FGF7,NME1,WNT7A,MIR29A,BAD,MIR10B,VEGFA,FGF1,B4GALT1,BMPR1A,GPBAR1,NRP1,CAV2,FGFBP1,MIR21,PTN,AR,MIR146A,STAT5A,JAML,SP1,CCND1,MIR130A,MIR503,MIRLET7B,CLDN1,TACR1,AGGF1,SOX9,PRKCA,XBP1,RTN4,ODAM,GHRL,PROK1 |
| 3.753e-03 | -5.59 | TAF4 (TATA-box binding protein associated factor 4) | protein interactions | 6874 | 142 | 55 | 19454 | 5460 |
HAPSTR1,TRIM21,EWSR1,RUVBL2,H3C1,RUVBL1,RIGI,TP53,ANAPC13,MAP1LC3B,JUN,ELF1,CBX3,TAF10,TAF2,H2AZ1,CBFB,CD274,HNRNPL,RHOH,PRNP,TAF7,IFI16,ZCCHC10,GTF2A2,SMCHD1,CDC23,TAF9,BRD3,RPA3,PML,NLE1,SPATA25,RNF113A,NUP50,SF3A1,SUPT3H,CDK7,KLF3,RPA2,DYRK2,CREB1,ELK3,GTF2A1,GTF2F2,SNRNP40,FBXO22,CBX5,ROCK1,VIRMA,ESR2,TAF11,CDC16,SP1,UBE2H |
| 3.753e-03 | -5.59 | Glutathione_S-Trfase | interpro domains | IPR040079 | 27 | 15 | 18521 | 5414 |
GSTP1,MTX2,GSTM3,GSTA1,GSTM2,GSTO2,EEF1G,GSTA2,GSTA4,GSTM5,GSTT1,GSTM4,GDAP1L1,CLIC2,CLIC4 |
| 3.761e-03 | -5.58 | positive regulation of DNA-binding transcription factor activity | biological process | GO:0051091 | 221 | 84 | 18204 | 5365 |
TLR9,TRIM22,TRIM52,EIF2AK2,PRKCQ,JUP,TLR2,TRAF6,MYD88,NLRP3,KIT,RGCC,CEBPG,BUD31,PPARG,FZD4,NEUROG2,UBE2N,TRIM26,AR,PTEN,MTPN,IKBKB,MAVS,RBCK1,TIRAP,SMARCB1,LRP6,TRIM15,DVL2,ESR2,HDAC5,COPS5,TRIM37,CLU,UBE2V1,PSMA6,TRIM34,IL18,AKT1,BCL10,DHX9,CD40,RPS6KA4,IL1B,SLCO3A1,PHB2,S100A8,NEUROD2,AGER,CD200,TRIM21,MTDH,TNFSF18,PYCARD,TLR4,TRIM5,STK3,DDIT3,IL1RAP,TRIM27,CD40LG,EP300,DDRGK1,TNF,TRIM68,SMAD3,ZC4H2,CRTC2,IL10,TRIM32,WNT2,TRAF1,IL6,TRAF2,CLEC7A,PPIA,TRIM62,TFRC,PRDX3,EDA2R,TRIM6,TRIM8,RPS3 |
| 3.764e-03 | -5.58 | COPB1 (COPI coat complex subunit beta 1) | protein interactions | 1315 | 266 | 95 | 19454 | 5460 |
UFL1,WBP2,EP300,HSPA8,SF3B1,TAPBP,HDAC5,VPS18,ARCN1,TANK,EDEM3,SEC62,RANBP6,ESR2,ARF1,LMBR1L,SEC61B,BRCA1,YWHAZ,POLR1B,RIT1,NTRK3,CUL3,MYC,ASF1A,TRIM37,PSMA1,KRAS,SACM1L,RAD21,ZC3H7A,KDELR1,EZH2,MOB3C,RNF126,RAF1,NAA15,EGLN3,PHB1,PRCC,AGR2,SKIC8,POU5F1,DDRGK1,XPO1,YWHAG,FBXW7,IRF7,RGS2,BCL6,SIRT7,PPM1G,RPA3,BAP1,FGFR1,RPA2,ACACA,UBE2M,SPTBN1,CFTR,CDK7,PRKCE,COPE,BCCIP,VIRMA,ENO1,PSMA6,CCNF,UQCRC2,PTEN,COPZ2,SNTA1,UBE2H,SERTAD1,ARF4,MEPCE,PC,RAB27A,CAPN2,TP53,FZR1,ARF6,ZBTB2,CDC5L,LMAN1,CD274,TES,H2AC4,STYK1,ID1,EMC4,FAM20C,MOV10,GOLPH3L,HDAC6 |
| 3.767e-03 | -5.58 | BRI3BP (BRI3 binding protein) | protein interactions | 140707 | 118 | 47 | 19454 | 5460 |
FAM241A,HNRNPL,DNAJC1,TMED9,HSD17B11,CD63,PHB1,COQ8A,RPN1,GDE1,YIPF3,DNAJC25,ADORA1,CCDC47,HS2ST1,TMT1A,CALU,UBE2H,TYROBP,TMED5,ESR2,SEC61B,LMBR1L,CCNF,GPR35,SIGMAR1,SSR1,DRD3,P2RY12,RPA2,SEC62,OTULINL,HCST,ATG16L1,RNF11,TSPAN5,LPAR1,RNF5,HSCB,SLC35F2,TMEM185A,VIPR1,TMEM106B,TSPAN15,CXCR4,LCA5,RPA3 |
| 3.767e-03 | -5.58 | MRPL14 (mitochondrial ribosomal protein L14) | protein interactions | 64928 | 118 | 47 | 19454 | 5460 |
VIRMA,ESR2,CCNF,MRPL53,MRPL13,RPS20,UBE2H,MTG2,AUH,MYC,CUL3,PMPCA,MRPL16,TUFM,RPS15,MRPL41,MRPL40,NGRN,GFM1,WRAP53,MTRES1,ATG16L1,MRPL10,MRPL12,FZR1,DYNC1I2,MRPL50,MALSU1,GATD3,MRPL18,ESYT1,GRSF1,MRPL9,SRPRB,FASTKD5,MRPL22,HNRNPDL,HSPD1,NDUFA4,LSM14A,PDHA1,FURIN,MRPL47,E2F4,MRPL11,EEF1A1,PPIF |
| 3.767e-03 | -5.58 | SPCS2 (signal peptidase complex subunit 2) | protein interactions | 9789 | 139 | 54 | 19454 | 5460 |
STK4,LAMP3,RAB5C,RHOG,RAC2,CLN8,HSD17B11,KCNA2,CD274,NUP35,DDX39A,JUN,TP53,CCDC47,ALPL,RPN1,NRN1,EMC2,SEC11A,TMT1A,TMEM87A,TOMM6,TOLLIP,KRAS,TM9SF4,MCAT,RIT1,LMNB1,SPCS3,SEC61B,DNASE1L1,LMBR1L,CCNF,FBXL14,SPCS1,LAMTOR3,ST7,SEC62,GPC4,OTULINL,PGRMC1,TOMM22,HNRNPH3,SSR1,RPA2,DERL1,SYVN1,PEBP1,RPA3,HSPA5,TSPAN5,GPC1,HSCB,EMC1 |
| 3.767e-03 | -5.58 | MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking) | protein interactions | 23041 | 139 | 54 | 19454 | 5460 |
EFNB1,IGF1R,TNFSF8,RAB3B,PDE2A,RIGI,B3GNT2,RAF1,TOP3B,MGARP,SIGLECL1,CA14,AQP3,RAB4A,PLD3,GJA1,LDLR,SPINT2,SPTAN1,STX6,CAV1,COMMD5,XPO1,P2RY10,DDRGK1,PEX3,ARMC8,RPA3,CD40,RAB9A,RAB5A,NPTN,HSCB,STX7,ATG16L1,BET1,NPY2R,PAAF1,SDC2,RPA2,FGFR1,STOM,S1PR4,CCNF,PTPMT1,ABHD12,ROCK1,ESR2,VIRMA,RAB11A,OPRM1,CUL3,LAMTOR1,NTRK3 |
| 3.772e-03 | -5.58 | nucleoside phosphate biosynthetic process | biological process | GO:1901293 | 254 | 95 | 18204 | 5365 |
NDUFS2,ADK,HACD2,GMPS,IDO1,MMUT,STOML2,DNAJC30,ACSL4,ATP5PB,NMRK1,ELOVL3,SLC25A1,NDUFV2,NDUFB6,DLAT,ACSS2,NDUFAB1,NME1,ATP5F1A,NDUFB10,PNP,NDUFS8,MTHFD2L,UCK2,UPRT,ATP5MC3,NDUFB7,NDUFA12,COX11,AK2,ELOVL7,RRM1,HACD1,DCAKD,NDUFB4,ADCY3,ATP6V1A,ADSS2,CMPK1,NDUFS3,ATP5F1E,AK3,NME4,GUK1,NDUFC2,NDUFS6,PRPSAP1,SDHC,NDUFB8,PAPSS2,DTYMK,AK5,LIPA,SLC52A3,ELOVL4,ATP5PO,KARS1,ATP5MG,PPT1,UCKL1,SHMT1,UQCC3,ATP5PD,NUDT2,PRPS1,NPR2,ATP5F1B,PPAT,NDUFA1,NDUFA5,PDHB,NME2,ATP5MK,DCTD,ELOVL6,UCK1,NPPC,ACACA,ELOVL1,TYMS,DCK,GUCY1B1,ADCY2,ATP5F1D,ATP5MC1,NDUFB5,ATP5PF,TECR,PDHA1,NUDT12,UMPS,NDUFA2,ACAT1,SDHB |
| 3.778e-03 | -5.58 | PYGB (glycogen phosphorylase B) | protein interactions | 5834 | 136 | 53 | 19454 | 5460 |
HNRNPAB,CUL3,PSMB2,SUGP1,MYC,ARL6IP6,HSD17B3,CYP1A1,UBE2H,ARMT1,COP1,SIAH1,PYGM,VIRMA,CFTR,RPA2,PML,SIRT7,RPA3,TMEM185A,HSPA8,CERS2,EMC1,PYGB,GAPDH,GPRASP2,HSPB8,TMA16,AGR2,SKIC8,HNRNPD,DDX1,GYS1,COMT,SSBP1,NDST3,PBDC1,PRNP,CAND1,CPNE1,GBE1,TXNRD1,TOP3B,STBD1,RAF1,UBR7,EEF1A1,EZH2,HNRNPA2B1,EMC2,ABCE1,XPNPEP1,TRIM37 |
| 3.778e-03 | -5.58 | SNX9 (sorting nexin 9) | protein interactions | 51429 | 136 | 53 | 19454 | 5460 |
SOS2,SLC2A8,BCKDK,PCGF3,KRAS,WASL,HNRNPK,FASLG,AP2S1,PIK3CA,TES,DNM2,PHB1,EGLN3,OCRL,HNRNPL,CSNK2A1,COPS5,PIK3R1,MPHOSPH6,ANAPC16,SNX33,EP300,RPA3,SLU7,DVL2,BAP1,SIRT7,SLC31A1,STAU1,CDC42,CFTR,RPA2,PAK2,PALS2,CTBP1,AP2M1,CSNK2B,CLXN,CCNF,LMBR1L,SRC,DAPK1,DAPK3,YES1,RUNX1,SLC1A3,CUL3,AP2A1,STK11,UBE2H,BRCA1,BICD2 |
| 3.778e-03 | -5.58 | MAU2 (MAU2 sister chromatid cohesion factor) | protein interactions | 23383 | 136 | 53 | 19454 | 5460 |
FAXC,WDR77,ACTL6A,RPLP0,LMNA,SF3B1,HNRNPH2,HSPA8,DDX5,MED13L,STK38,PRPF31,NONO,CEP70,HNRNPC,BRCA1,PRMT5,CFAP298,TUBA1B,CBX5,APEX1,GNAI2,MATR3,EEF1A1,ARFGAP1,RPSA,MOB3C,RPN1,CBX3,HAPSTR1,RUVBL2,GPSM3,PALM2AKAP2,TOP2B,HNRNPA2B1,RFC2,RIGI,SSRP1,POLDIP3,NUP107,HNRNPF,HNRNPK,THRAP3,RUVBL1,GAPDH,PRPF19,DNAJC7,KPNA1,FABP5,FUBP3,HSP90AB1,SLAIN2,TOP1 |
| 3.778e-03 | -5.58 | LLPH (LLP homolog, long-term synaptic facilitation factor) | protein interactions | 84298 | 136 | 53 | 19454 | 5460 |
EIF2AK2,RPS3,PSPC1,PRKRA,RPL37A,ESR2,SRPK2,RPL7A,MYC,ZSCAN25,FTSJ3,DCAF4,RPS5,NLE1,RNF113A,RPL4,RPS15,BRIX1,AATF,KLF12,MACROH2A2,ZNF770,ZNF574,RPL26L1,RPLP0,KRR1,RPL12,HP1BP3,CGAS,RPS16,SURF6,DKC1,CMSS1,IFI16,GRSF1,DDRGK1,AGR2,RPS2,RPL31,RPL3,H1-6,RPL17,RPS13,SRSF12,MAGEB10,RAF1,STRBP,RPL15,TAF1D,H2AX,AURKAIP1,RBM34,GLE1 |
| 3.779e-03 | -5.58 | establishment of protein localization to membrane | biological process | GO:0090150 | 230 | 87 | 18204 | 5365 |
TIMM8A,SEC61B,WDR83OS,SEC61A1,EMC1,VAMP3,TRMT10B,ATP1B1,SRPRA,ATG3,TRAM1L1,ARL6,ATAD1,PEX3,VAMP2,TOMM20,TIMM8B,RAB31,GOLPH3L,EMC6,RAB11B,UBL4A,TOMM22,PEX26,ZDHHC4,ZDHHC24,TIMM10,SSR3,NSG1,ROMO1,SPTBN1,EMC4,EMC2,TIMM13,RAB11A,SEC63,RILPL2,SLC1A1,SRP14,GOLGA7B,TRAM2,SRP72,AGK,HSPA5,CCDC47,MTX2,SGTA,GORASP2,AQP11,VAMP5,TOMM7,EMC8,TIMM29,EMC9,MAIP1,GOLGA7,SEC62,SAMM50,SRP54,SYS1,TOMM6,OPTN,SEC61A2,LARGE1,ADORA1,TRAM1,SNAP25,EMC10,MTCH2,TMEM147,HSP90AA1,TOMM70,ZDHHC14,PREPL,BCS1L,SEC61G,SDCBP,ZDHHC15,SRPRB,ZFAND2B,CAMLG,SSR1,SSR2,TOMM40,RAB8B,RTP4,BAX |
| 3.780e-03 | -5.58 | PCCA (propionyl-CoA carboxylase subunit alpha) | protein interactions | 5095 | 121 | 48 | 19454 | 5460 |
LGALS3,NDN,PTEN,PHF21A,CCNF,TBC1D25,DCAF4,TRIM23,TAFAZZIN,PCCB,NTAQ1,MRM2,PNPLA4,MYC,MTG2,KDM1A,THBS3,TTC1,HSPA8,PML,RPA3,ACACA,FAM81A,DCTN4,RPA2,DET1,MALSU1,HNRNPL,FAHD1,ARL4D,YBEY,UBE2N,ARL10,HDHD3,PSME2,AGR2,LAMP3,ISX,SAR1B,RIGI,ARF4,ARL5B,HUWE1,PC,THG1L,TP53,ERRFI1,KBTBD4 |
| 3.780e-03 | -5.58 | ARFGAP1 (ADP ribosylation factor GTPase activating protein 1) | protein interactions | 55738 | 121 | 48 | 19454 | 5460 |
MED27,FAM20C,RAB23,YWHAH,XPO1,COPS5,SPRED2,HRAS,STX5,KDELR1,TFRC,AP2S1,DLG3,KBTBD4,FNTB,MAP1LC3B,GABARAPL1,LASP1,CYTH2,RFC3,SMN1,ARFGAP3,TRIM23,SLC6A1,AP2A1,CRMP1,RAB11A,MYC,GSTM5,PRKACB,ESR2,RPL22,SEC63,OPTN,ARF1,SEC61B,AP2M1,RPA2,RDH12,GABARAPL2,CD2AP,RGS2,FOS,PML,RPA3,INPPL1,TCEA1,HSPA8 |
| 3.780e-03 | -5.58 | RALA (RAS like proto-oncogene A) | protein interactions | 5898 | 121 | 48 | 19454 | 5460 |
LAMP2,HDAC6,EXOC1,SMAD4,NOS1AP,EXOC2,HSPB1,HRAS,HNRNPL,ARF6,PRNP,MARCKSL1,RAF1,GPT,EXOC3,NDUFS6,ATP5PF,ABCE1,SLC16A1,KRAS,RAB8B,RGL2,MYC,EXOC5,NONO,USP14,ZNHIT3,RHOB,EXOC8,UBE2H,ARF1,CYB5R3,RHOJ,LAMTOR3,ATP6AP2,ESR2,AKR7A2,MPV17,CDC42,RPA2,VPS4B,LSM2,FAM3C,CXCR4,RPA3,PMAIP1,EMC1,HSCB |
| 3.781e-03 | -5.58 | regulation of osteoclast differentiation | biological process | GO:0045670 | 71 | 32 | 18204 | 5365 |
FOS,TNF,TYROBP,NOTCH2,IL12B,IFNG,TLR3,CCR1,TFE3,SFRP1,CREB1,TNFAIP6,CTNNB1,IL23A,MITF,TOB2,UBASH3B,BGLAP,PPP3CA,CCL3,PIK3R1,IL4,KLF10,LILRB1,TCTA,TRAF6,EEIG1,FBXW7,TLR4,LILRB4,CARTPT,GPR137 |
| 3.781e-03 | -5.58 | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological process | GO:0051898 | 71 | 32 | 18204 | 5365 |
EPHA2,MIR206,NOP53,PPP2R1A,DAG1,INPP5K,MIR34C,MIR20A,DLG1,DDIT3,MTM1,DRD3,MIR146A,PPARA,MIR449A,BTN2A2,MIR375,SIRT7,MUL1,CRYBA1,MIR29C,PTEN,NHERF1,MIR34B,MSTN,INPP5E,MIR34A,MIR29A,HYAL2,FLCN,MIR145,STAMBP |
| 3.781e-03 | -5.58 | positive regulation of endothelial cell proliferation | biological process | GO:0001938 | 110 | 46 | 18204 | 5365 |
APLN,SCG2,AKT3,AKT1,CXCL12,MIR132,FGF7,TNFSF12,HMGB1,FGFR1,MIR495,VEGFC,APLNR,MIR23A,EMC10,PROX1,CDH13,SEMA5A,CCL11,MIR10A,IL10,MIR101-1,POLD4,CCR3,EGFL7,MIR135B,CCL24,MIR126,FGF10,AGGF1,PROK1,GHRL,PRKCA,MIR146A,STAT5A,FGFBP1,MIR21,MIRLET7B,MIR130A,MIR503,SP1,CAV2,NRP1,MIR10B,MIR29A,VEGFA |
| 3.782e-03 | -5.58 | lymphocyte proliferation | biological process | GO:0046651 | 130 | 53 | 18204 | 5365 |
MEF2C,IL7,FKBP1B,IL23A,FOSL2,CD28,NCSTN,RC3H2,GAPT,IL2RA,IL15,IFNB1,CD151,TICAM1,IFNA2,DLG1,MSN,LIPA,IL2,EFNB1,PRKCQ,NDFIP1,ALKBH5,GJA1,IFNK,HELLS,CD38,IL20RB,EMP2,PSMB10,IFNA10,SELENOK,CCND3,GPAM,BAX,IDO1,IL10,TP53,IL12B,LMBR1L,PIK3CG,TNFSF18,PELI1,CD40LG,TLR4,IFNA13,FOXP3,BCL6,HSPD1,LILRB1,CD40,SASH3,PRDX2 |
| 3.783e-03 | -5.58 | response to bacterial lipoprotein | biological process | GO:0032493 | 11 | 8 | 18204 | 5365 |
CD36,TLR6,TLR1,TLR10,TIRAP,CD14,TLR2,MIR105-1 |
| 3.783e-03 | -5.58 | ubiquitin recycling | biological process | GO:0010992 | 11 | 8 | 18204 | 5365 |
TRIM6,UBE2S,UBE2K,PLAA,IDE,VPS54,FBXW7,TRIM32 |
| 3.783e-03 | -5.58 | TRIF-dependent toll-like receptor signaling pathway | biological process | GO:0035666 | 11 | 8 | 18204 | 5365 |
IRF3,TICAM1,TLR6,TLR4,TICAM2,IKBKB,TRAF6,CD274 |
| 3.783e-03 | -5.58 | interleukin-15-mediated signaling pathway | biological process | GO:0035723 | 11 | 8 | 18204 | 5365 |
IL2RB,CD4,STAT5A,JAK1,IL2RG,IL15RA,PLCB1,IL15 |
| 3.783e-03 | -5.58 | cellular response to interleukin-15 | biological process | GO:0071350 | 11 | 8 | 18204 | 5365 |
CD4,IL2RB,JAK1,IL2RG,STAT5A,PLCB1,IL15RA,IL15 |
| 3.787e-03 | -5.58 | ACACB (acetyl-CoA carboxylase beta) | protein interactions | 32 | 124 | 49 | 19454 | 5460 |
CDK17,ARL10,NT5DC1,RGS1,EED,POU5F1,TESK1,HMGA1,VRK1,RBBP7,HUWE1,PAK6,SAR1B,ARF4,ZC3H7A,POC1B,RBBP4,FBXO22,SNRNP40,DAPK3,VIRMA,MID1IP1,CCNF,PTEN,PHF21A,GSK3A,SMU1,DCAF4,TRIM23,DCAF16,COP1,RAB11A,CIAO1,NXPH3,MLF1,KDM1A,FOS,SLU7,RPA3,ACACA,CSNK1G3,OXSR1,PAFAH1B1,WDR5B,ATG16L1,DET1,DUSP22,CDK7,ELP3 |
| 3.790e-03 | -5.58 | DNA-templated transcription initiation | biological process | GO:0006352 | 159 | 63 | 18204 | 5365 |
OGG1,POLR3H,GTF2A1,GTF3C4,TFB1M,MED27,GTF2E2,SMARCB1,MACROH2A1,WBP2,EGR1,CDK9,SPHK2,MED4,TAF11,MED29,MED31,MNAT1,GTF2E1,SNAPC5,RRN3,CDK7,POLR2I,NIBAN2,APOBEC3F,TAF2,CCNH,PAAF1,ZMPSTE24,APOBEC3A,PADI2,ELOC,MED23,GTF2F1,MED9,VPS72,TAF9,TRMT112,GTF2H5,SIRT7,TP53,MED17,APEX1,ERCC3,GTF2B,DPY30,TAF7,TAF10,EP300,DR1,POLR2G,MED22,GTF2A2,APOBEC3C,SGF29,MED21,MED11,GTF2F2,MED30,SMARCA5,POLR2D,MED10,GTF2H2 |
| 3.790e-03 | -5.58 | ANAPC5 (anaphase promoting complex subunit 5) | protein interactions | 51433 | 130 | 51 | 19454 | 5460 |
CRYL1,SKP1,RPA3,HSPA8,ANAPC16,EP300,RPA2,RPS14,NEK2,CDC20,MAD2L1,SMURF1,ESR2,DYRK1A,APEX1,CCNF,LMBR1L,CIB2,UBE2S,PTEN,ANAPC2,ANAPC4,CDC16,CREBBP,CUL3,ANAPC15,H3C1,ZBTB16,KRAS,PSMA5,BACH1,MDC1,PABPC1,BAG2,GRAP2,ANAPC13,SOX2,FZR1,EGLN3,NAA11,TRAK2,H2AC4,AKAP8L,CDC23,VCPIP1,BRD3,UBXN6,CDC26,GTF2E1,HSPB8,XPO1 |
| 3.790e-03 | -5.58 | SCAF4 (SR-related CTD associated factor 4) | protein interactions | 57466 | 130 | 51 | 19454 | 5460 |
PSENEN,RPL4,OXCT1,RPA3,BAP1,SNRPA,TXNDC17,EP300,MTDH,VAPB,RPA2,TRIM68,RPRD1B,RPLP0,SUMO1,FGF13,MED17,FBXO22,SNRNP40,SUCLG2,SH3BGRL,POLR2B,ESR2,SRPK2,TNPO3,POLR2F,MED10,MYC,SNRPB,CHCHD2,SSRP1,ZNF287,POLR2C,POLR2G,POLR2D,RAF1,SUPT5H,RPAP2,RPL35A,TOP1,POLR2I,RPRD1A,POLR2L,EED,MED27,MED21,SNRNP70,CDK12,MED4,HNRNPA1,KLHL22 |
| 3.791e-03 | -5.58 | ATP6V0A2 (ATPase H+ transporting V0 subunit a2) | protein interactions | 23545 | 127 | 50 | 19454 | 5460 |
LGALS8,LAMTOR1,COX11,DNAJC5,BTF3,RNF148,AKT1,CLCN6,ATP6AP2,ACP2,B4GALT3,RPL10L,RAB14,STUM,VAMP3,SLC25A3,FTH1,OTULINL,ATP6V0E1,ATP6V1C1,CERS6,ATP6V1G2,EMC1,CERS2,RPS15,TMEM185A,EMP3,PPY,ATP6V1D,RPS2,SLC2A1,PLPP4,EDEM1,LAMP2,TMEM199,CAV1,RAB1B,TTC9C,CD4,RNF128,STK16,STX12,SFTPC,PTRH2,DNAJC25,MARCKSL1,ATP5PB,CYTH2,SAR1B,RAB1A |
| 3.791e-03 | -5.58 | GOLPH3 (golgi phosphoprotein 3) | protein interactions | 64083 | 127 | 50 | 19454 | 5460 |
RPA2,P2RY12,FAM3C,ARCN1,ARHGAP1,COQ8B,UBLCP1,SRM,NME4,TPST1,TSR3,MARS1,CMAS,TMEM106B,RPA3,DUSP9,CXCR4,PFDN4,ST3GAL1,CAP2,B4GALT4,COPE,JAK2,VAMP3,CCNF,SEC61B,TMEM101,RANBP1,DIPK1A,PGAP4,MDC1,GALNT2,AP1M1,NDUFA4,RUVBL2,BPNT2,FKBP4,RASSF8,PFDN5,GMPPA,GMPPB,FAM20B,XPO1,DCUN1D1,SSBP1,COQ8A,GLT8D1,RB1,EXT1,DIPK2A |
| 3.802e-03 | -5.57 | Transmission across Chemical Synapses | REACTOME pathways | R-HSA-112315 | 217 | 87 | 10285 | 3229 |
CHRNB2,GNG2,NPTN,SLC6A12,GNG12,TSPAN7,SLC6A3,RAF1,PRKCA,PRKACB,GNB1,GABBR1,HSPA8,SLC38A1,KCNJ3,SLC32A1,GNG7,SLC1A3,CHRNA7,MYO6,GRIA1,ADCY3,PICK1,STX1A,MDM2,PPFIA3,GABRG2,SLC6A1,RAB3A,CREB1,SNAP25,PLCB2,GABRB2,DLG4,GRIK1,ADCY2,GNG13,KCNJ2,AP2A1,GNG10,GNG5,PLCB1,LIN7C,COMT,KCNJ10,DLG3,CACNB4,DNAJC5,GABRB3,PPFIA2,MIR197,GABRA2,SLC1A1,NEFL,LIN7B,CPLX1,GABRA1,SLC1A2,DLG1,ACHE,NCALD,GLUL,GNB4,ARL6IP5,CASK,SYN3,CACNG3,GRIA2,GNAI2,CAMK2G,GNGT2,GNB3,STXBP1,PRKCB,GAD2,CACNB3,GNAI3,GNG3,VAMP2,SLC6A4,AP2M1,CACNB2,SLC6A11,SLC38A2,AP2S1,GNG11,HRAS |
| 3.806e-03 | -5.57 | methyltransferase complex | cellular component | GO:0034708 | 100 | 42 | 19108 | 5553 |
RBM15B,CXXC1,RUVBL2,PELP1,TAF7,INO80C,VIRMA,SNRPD1,SNRPB,SNRPD3,HCFC2,EPOP,RUVBL1,EZH2,EED,WDR5B,PRMT5,MAX,METTL14,SNRPD2,PRDM4,ERH,WTAP,PAGR1,DPY30,WDR77,PHF1,HSD17B10,RBBP7,E2F6,CBLL1,TRIM37,CBX5,PRPF31,TAF9,RBBP4,TRMT6,EZH1,WDR82,TRMT61A,SNRPE,SNRPG |
| 3.806e-03 | -5.57 | P-body | cellular component | GO:0000932 | 100 | 42 | 19108 | 5553 |
APOBEC3C,CPEB1,SQSTM1,CNOT7,AGO1,TNRC6C,C9orf72,MOV10,APOBEC3D,LSM14A,ISG20,LSM3,CNOT2,APOBEC3A,EIF4E,PSMC3,TRIM5,IGF2BP1,APOBEC3G,TRIM21,EIF4E2,APOBEC3B,POLR2G,CNOT8,GARRE1,HAX1,EDC3,LSM4,PSMA6,PSMA4,PNRC1,CARHSP1,APOBEC3H,PSMA2,DCP2,LSM2,YTHDF1,RC3H2,LSM6,YTHDF2,TOP1,APOBEC3F |
| 3.828e-03 | -5.57 | DNA cytosine deamination | biological process | GO:0070383 | 9 | 7 | 18204 | 5365 |
APOBEC3F,APOBEC3A,APOBEC3D,APOBEC3C,APOBEC3H,APOBEC3B,APOBEC3G |
| 3.828e-03 | -5.57 | establishment of protein localization to chromatin | biological process | GO:0071169 | 9 | 7 | 18204 | 5365 |
LRWD1,MACROH2A2,RUVBL2,MACROH2A1,WBP2,SGF29,H1-5 |
| 3.828e-03 | -5.57 | positive regulation of cardiac muscle hypertrophy in response to stress | biological process | GO:1903244 | 9 | 7 | 18204 | 5365 |
MIR34B,MIR208A,MIR20A,MIR214,MIR17,PPP3CA,MIR34C |
| 3.828e-03 | -5.57 | regulation of chronic inflammatory response | biological process | GO:0002676 | 9 | 7 | 18204 | 5365 |
IDO1,FOXP3,IL10,TNFAIP3,LTA,CCL5,TNF |
| 3.828e-03 | -5.57 | positive regulation of cardiac muscle adaptation | biological process | GO:0010615 | 9 | 7 | 18204 | 5365 |
MIR208A,MIR34B,MIR17,MIR214,PPP3CA,MIR20A,MIR34C |
| 3.828e-03 | -5.57 | amyloid-beta formation | biological process | GO:0034205 | 9 | 7 | 18204 | 5365 |
NCSTN,PSENEN,BACE1,PSEN2,APH1A,DYRK1A,PSEN1 |
| 3.828e-03 | -5.57 | epithelial cell proliferation involved in prostate gland development | biological process | GO:0060767 | 9 | 7 | 18204 | 5365 |
SOX9,WDR77,STK11,EAF2,CDKN1B,CTNNB1,NKX3-1 |
| 3.828e-03 | -5.57 | negative regulation of cellular extravasation | biological process | GO:0002692 | 9 | 7 | 18204 | 5365 |
PLCB1,CCL21,CXCL12,PTGER4,CCL25,MIR146A,CCL28 |
| 3.828e-03 | -5.57 | substrate-dependent cell migration, cell extension | biological process | GO:0006930 | 9 | 7 | 18204 | 5365 |
P2RY12,OPHN1,SDCBP,CD2AP,NCK1,NRP1,CTTN |
| 3.831e-03 | -5.56 | NFIA (nuclear factor I A) | protein interactions | 4774 | 188 | 70 | 19454 | 5460 |
E2F6,PAX9,LUC7L3,KLF4,LMNA,KLF3,ADNP,ZNF326,KLF12,SAP18,COIL,TRA2B,EP300,RLIM,FOS,SMAD2,RRP7A,FTSJ3,FBXO7,AR,HNF1B,CREBBP,MYC,SFN,SNRNP40,RPL37A,QSER1,CREB1,MIDEAS,ELK3,ATXN1L,RBPJ,RPS11,SSBP3,IRF8,SURF4,GABARAPL1,SOX2,EGR2,ELF1,SOX9,TPBG,RPS13,PAX6,FOXP4,H3C1,ZNF609,RPS24,DHX9,BCL9,SRSF7,LHX2,BRD3,FOXP1,SMAD4,AGR2,BCL7C,XPO1,TRA2A,DPY30,IRF4,FOXC2,TLE1,SRSF10,HMG20A,PLEKHF2,HNRNPL,HP1BP3,SSBP1,SMAD3 |
| 3.833e-03 | -5.56 | endolysosome membrane | cellular component | GO:0036020 | 20 | 12 | 19108 | 5553 |
TLR7,AP2S1,TLR3,TASL,LDLR,AP2A1,RNF167,TLR8,PCSK9,AP2M1,ATG16L1,TLR9 |
| 3.844e-03 | -5.56 | zf-RING_UBOX | pfam domains | PF13445 | 42 | 21 | 17795 | 5224 |
TRIM46,TRIM36,TRIM63,TRIM6,TRIM5,TRIM22,TRIM23,RMND5B,TRIM8,RBCK1,TRIM35,TRAF7,TRIM32,RNF222,SHPRH,TRIM45,TRIM34,TRIM54,RNF10,MAEA,RNF39 |
| 3.846e-03 | -5.56 | duodenum | COSMIC cancer mutations | duodenum | 35 | 18 | 16828 | 4835 |
SMAD4,SF3B1,STK11,KRAS,HRAS,NTRK3,SMARCB1,PIK3CA,FGFR1,FBXW7,CDKN2C,AKT1,PTPN11,JAK2,TP53,CTNNB1,MET,KIT |
| 3.847e-03 | -5.56 | RL2 (contains a RING finger; disrupts ND10; proteasome-dependent degradation of several cellular proteins; involved in gene regulation; involved in cellular protein degradation; involved in latency) | protein interactions | 2703390 | 23 | 13 | 19454 | 5460 |
SRC,RANBP10,SIAH1,SUMO3,YES1,SUMO2,HDAC5,PML,RNF8,CBL,UBE2D1,SUMO1,NFKB1 |
| 3.847e-03 | -5.56 | Cct7 (chaperonin containing TCP1 subunit 7) | protein interactions | 12468 | 23 | 13 | 19454 | 5460 |
PTEN,CCT8,TUBA1B,CCNF,PDCD5,TCP1,DNAAF10,TUBB,CCT5,PDCL,DTL,ACTR2,CCT2 |
| 3.847e-03 | -5.56 | RAB17 (RAB17, member RAS oncogene family) | protein interactions | 64284 | 23 | 13 | 19454 | 5460 |
CSTPP1,GTPBP1,BOLA1,ACVR1,TFRC,NUDT3,RAF1,DBT,HNRNPL,S100A8,RABAC1,RABGGTB,BOLA3 |
| 3.847e-03 | -5.56 | ODC1 (ornithine decarboxylase 1) | protein interactions | 4953 | 23 | 13 | 19454 | 5460 |
CSNK2B,OAZ3,ESR2,ODC1,OAZ2,GORASP2,CSK,TMOD1,OAZ1,TDRD7,SSR1,STX17,MAP2K1 |
| 3.847e-03 | -5.56 | ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8) | protein interactions | 29801 | 23 | 13 | 19454 | 5460 |
RHOG,DCAF4,RHOB,TOP3B,CDC42,KRAS,ARF6,RHOJ,CLDND1,CAV1,RHOU,GJA1,RAC2 |
| 3.847e-03 | -5.56 | TLR1 (toll like receptor 1) | protein interactions | 7096 | 23 | 13 | 19454 | 5460 |
MAVS,TLR2,TBC1D24,HSPD1,TLR4,TLR6,CNPY3,LRP6,TLR5,HSP90B1,TLR9,TLR10,EZH2 |
| 3.847e-03 | -5.56 | SLC9A9 (solute carrier family 9 member A9) | protein interactions | 285195 | 23 | 13 | 19454 | 5460 |
TP53,RAB5C,COX5A,OPRM1,ATP5MC1,TFRC,STT3A,VDAC2,VDAC1,ARF6,FLOT1,GNB1,ZDHHC17 |
| 3.847e-03 | -5.56 | DDX4 (DEAD-box helicase 4) | protein interactions | 54514 | 23 | 13 | 19454 | 5460 |
MARCHF5,CUL3,TOR1AIP2,HEXIM1,RND3,CHMP4C,SMAD3,SPSB1,MEPCE,PIWIL2,SRC,CAND1,DCUN1D1 |
| 3.847e-03 | -5.56 | Skic8 (SKI8 subunit of superkiller complex) | protein interactions | 66317 | 23 | 13 | 19454 | 5460 |
CDC73,TRAPPC13,PFDN2,PFDN6,CCT2,ACVR1,CCT5,PPP1R10,SMURF1,PFDN1,CCT7,TCP1,CCT8 |
| 3.863e-03 | -5.56 | BORCS5 (BLOC-1 related complex subunit 5) | protein interactions | 118426 | 41 | 20 | 19454 | 5460 |
YWHAH,YWHAG,INSYN1,BORCS6,LAMP2,KXD1,TP53,LAMTOR2,BORCS8,YWHAB,BCAS4,LAMTOR1,YWHAZ,RAB9A,FBXO25,STX11,PIP4P1,BORCS7,VRK1,LAMTOR3 |
| 3.863e-03 | -5.56 | OGDHL (oxoglutarate dehydrogenase L) | protein interactions | 55753 | 41 | 20 | 19454 | 5460 |
RP2,SIAH1,GPM6A,KGD4,GJB1,HSCB,EMC1,MDM2,KMT5B,LIG3,NFKBIA,MGME1,DLST,SSBP1,ACBD7,HSPD1,EP300,CDK4,TOP3B,CSNK2A1 |
| 3.863e-03 | -5.56 | BIN3 (bridging integrator 3) | protein interactions | 55909 | 41 | 20 | 19454 | 5460 |
ERH,SEC63,MAD2L2,GTF3C3,PYGB,SNX1,TOP1,COG1,SNX33,PICK1,SYNCRIP,SNX5,FBXO8,BICD2,RPRD1B,GINS4,CDC42,XPO1,ATG16L1,UBL5 |
| 3.863e-03 | -5.56 | GNG10 (G protein subunit gamma 10) | protein interactions | 2790 | 41 | 20 | 19454 | 5460 |
CCR1,PDCL,GNAI3,GNAZ,GNAQ,FYTTD1,BTF3,UBR7,GTF2E2,GNB4,GNB1,ESR2,GNAI2,GNAO1,RAMAC,PCGF2,GNB3,SNAPC1,GNA11,PPY |
| 3.865e-03 | -5.56 | ORC1 (origin recognition complex subunit 1) | protein interactions | 4998 | 80 | 34 | 19454 | 5460 |
MCM6,SKP1,FTL,RFC3,KRAS,NFIL3,CHMP1B,TRIM26,XRCC5,SRP72,RPA2,CDK1,CCNA2,TOP3B,CKS1B,MRPL11,TP53,POLE3,CDC5L,LRWD1,VIRMA,ESR2,CDC7,CSNK2B,RB1,CDIPT,ZNF174,TNFRSF1B,MGMT,CIRBP,XPO1,MCM4,MYC,ORC5 |
| 3.865e-03 | -5.56 | PIAS3 (protein inhibitor of activated STAT 3) | protein interactions | 10401 | 80 | 34 | 19454 | 5460 |
HNRNPK,TRIM63,SATB1,PSMC1,FOXP2,SNIP1,GLUL,PML,EP300,SNAI2,CARHSP1,TAB2,SUMO1,TP53,GFI1,PGR,SIAH1,SUMO3,MITF,SUMO2,ESR2,SMAD3,TRIM27,UBE2I,SPOP,SMAD4,BECN1,SMAD2,CSK,CREBBP,TRIM32,TRIM8,AR,SIAH2 |
| 3.865e-03 | -5.56 | PLEKHO1 (pleckstrin homology domain containing O1) | protein interactions | 51177 | 80 | 34 | 19454 | 5460 |
AKT1,IFI35,AKT3,CCNB1,PLEKHO1,CSNK2A1,TRAF6,FTSJ3,GTPBP2,VAMP3,HRAS,TRAF3IP3,PSMC5,RPS20,MMD,TSPO2,SMURF1,CEP19,SMAD5,TRMT1L,TRAM1L1,SUPT5H,JUN,CAPZA2,RPL26L1,AKT2,NLE1,LRP10,RPL3,PDIA6,TNF,KRAS,STAU1,CAPZA1 |
| 3.869e-03 | -5.55 | positive regulation of adaptive immune response | biological process | GO:0002821 | 133 | 54 | 18204 | 5365 |
LTA,IL23A,B2M,CD28,FCGR1A,EXOSC3,MAD2L2,HMCES,JAK2,STX7,CLEC6A,CCR2,IL2,MIR21,CD4,CYRIB,CD81,TNFSF13,TRAF6,NLRP3,PRKCQ,CD1B,CD1C,IL4,TRAF2,RSAD2,SHLD1,CLEC7A,IL6,KMT5B,TFRC,EP300,TNF,CD1E,IL12B,XCL1,IL6ST,MICB,STAT6,PYCARD,NECTIN2,CD1A,CD226,SASH3,CD1D,IL18,CD274,HFE,IL12A,FOXP3,HSPD1,CD40,HSPA8,IL1B |
| 3.870e-03 | -5.55 | granulocyte migration | biological process | GO:0097530 | 96 | 41 | 18204 | 5365 |
CXCL11,CCL24,PPIA,CCL4L1,JAGN1,SELENOK,CCL18,TGFB2,CX3CL1,XCL1,FCER1G,LGALS3,DPEP1,CXCL9,CXCL10,CXCL8,CCL5,CCL2,SRP54,CXCL1,PDE4B,PIK3CG,CXCL3,ADGRE2,CXCL13,JAML,CCL11,S100A8,CCL8,CCL25,SCG2,CXCR1,PPIB,CCL23,IRAK4,IL1B,CCL1,SYK,EMP2,CCL3,CKLF |
| 3.870e-03 | -5.55 | negative regulation of developmental growth | biological process | GO:0048640 | 96 | 41 | 18204 | 5365 |
STK4,NRP1,CDKN1A,MECP2,FOXP1,PTEN,MIR873,SLC6A4,RGMA,MT3,FGF13,SOCS2,MSTN,CAV3,VGLL4,GSK3A,MIR1-1,PLAC8,SAV1,TNR,G6PD,PI16,MIR25,RGS2,CDK5,SPP1,ADRB3,RTN4,CDKN1B,IFRD1,PPARA,ADRB2,STK3,DUSP10,TOMM70,FXN,SEMA5A,NOG,HDAC6,ADRB1,TRIM46 |
| 3.873e-03 | -5.55 | ileum | COSMIC cancer mutations | ileum | 25 | 14 | 16828 | 4835 |
SMARCB1,PIK3CA,IDH2,FBXW7,PTPN11,JAK2,TP53,CTNNB1,KIT,SMAD4,STK11,IDH1,KRAS,HRAS |
| 3.873e-03 | -5.55 | dysplasia-carcinoma_in_situ | COSMIC cancer mutations | dysplasia-carcinoma_in_situ | 25 | 14 | 16828 | 4835 |
GNAQ,MAP2K1,IDH1,HRAS,KRAS,PTEN,TERT,PIK3CA,AKT1,IDH2,GNA11,KIT,CTNNB1,TP53 |
| 3.873e-03 | -5.55 | skull | COSMIC cancer mutations | skull | 25 | 14 | 16828 | 4835 |
SMARCB1,PTEN,PIK3CA,AKT1,JAK2,IDH2,CTNNB1,RB1,KIT,TP53,EWSR1,IDH1,KRAS,HRAS |
| 3.873e-03 | -5.55 | biliary_tract-gallbladder-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-squamous_cell_carcinoma | 25 | 14 | 16828 | 4835 |
GNAQ,MAP2K1,KRAS,HRAS,FGFR1,PIK3CA,CTNNB1,KIT,MET,TP53,AKT1,JAK2,PTPN11,FBXW7 |
| 3.881e-03 | -5.55 | SMAP2 (small ArfGAP2) | protein interactions | 64744 | 185 | 69 | 19454 | 5460 |
TOP3B,CCT5,YTHDF2,TNRC6C,MSX2,TFRC,RAB4A,AQP3,HGS,FURIN,SCYL2,GARRE1,PABPC1,SLC25A11,BHLHE40,ZC3H7A,RUVBL2,FAM168A,BAG2,G3BP1,RUVBL1,PFDN1,ARF4,RIGI,ATG9A,LAMP2,PFDN5,YWHAG,XPO1,LAMP3,CPEB1,YWHAH,NOS1AP,STAMBPL1,SMAD9,FUBP3,SPPL3,TCP1,PEG10,CNTROB,STX6,TMEM45B,CCT7,NOTCH2,AGO1,SYNRG,RBMS2,LARP4B,FGFR1,PICALM,MCRIP2,LSM12,SYVN1,SMG5,YTHDF1,STAU1,STX7,CRYZ,RAB11A,CEP85,LAMTOR1,CCT2,RC3H2,AP2A1,PFDN2,CDIPT,CCNF,SLC22A12,PRRC2A |
| 3.881e-03 | -5.55 | ZFP36L1 (ZFP36 ring finger protein like 1) | protein interactions | 677 | 28 | 15 | 19454 | 5460 |
CNOT6,KLHL23,BAP1,EGLN3,PRNP,PAFAH1B2,DCP2,YWHAH,YWHAG,XPO1,SFN,AKT1,YWHAB,DCAF4,YWHAZ |
| 3.881e-03 | -5.55 | ARMCX2 (armadillo repeat containing X-linked 2) | protein interactions | 9823 | 28 | 15 | 19454 | 5460 |
TULP3,NDUFA2,TOMM22,FIS1,EZH2,AKAP1,MAVS,RMDN3,PML,EXD2,OPTN,MAD2L2,ARMCX2,CHCHD3,LYAR |
| 3.881e-03 | -5.55 | BAHCC1 (BAH domain and coiled-coil containing 1) | protein interactions | 57597 | 28 | 15 | 19454 | 5460 |
ING1,EGR2,SAP30,TOP3B,UBE2M,GSTP1,FOSL2,ATP5IF1,ING2,GATAD1,PIAS1,VIRMA,RBBP7,RBBP4,TGIF2LX |
| 3.881e-03 | -5.55 | PPARGC1B (PPARG coactivator 1 beta) | protein interactions | 133522 | 28 | 15 | 19454 | 5460 |
ZNF200,PPARA,AKT1,H1-1,ZNF513,DNAJC10,PPARG,ZFP64,SYVN1,SRC,VIRMA,PIAS1,NR1H2,HNRNPL,SPPL3 |
| 3.881e-03 | -5.55 | RCOR2 (REST corepressor 2) | protein interactions | 283248 | 28 | 15 | 19454 | 5460 |
NOL4,ZMYM3,CTBP1,HDAC11,DCAF12L2,S100B,ZNF174,ZMYM2,PHF21A,TRIM24,KDM1A,ZSCAN5A,DYNLL1,SUMO2,HMG20A |
| 3.881e-03 | -5.55 | HINT3 (histidine triad nucleotide binding protein 3) | protein interactions | 135114 | 28 | 15 | 19454 | 5460 |
TFCP2,SMAD2,EIF1AX,DHRS3,TP53,TMEM38B,ESS2,FBXO7,MID1IP1,UBP1,SMAD3,HRAS,RHOU,PTPMT1,HINT1 |
| 3.923e-03 | -5.54 | oxidoreductase activity, acting on a heme group of donors | molecular function | GO:0016675 | 13 | 9 | 18094 | 5411 |
COX5A,CYGB,COX8A,COX6B1,CYB5A,COX7B,COX4I1,COX4I2,COX7A1 |
| 3.929e-03 | -5.54 | THG1L (tRNA-histidine guanylyltransferase 1 like) | protein interactions | 54974 | 63 | 28 | 19454 | 5460 |
MRPL11,MTRES1,ELMOD1,SH3GLB2,SH3GLB1,PLS3,SDCBP,RPA2,ARPC2,THG1L,HINT2,HSPD1,FBXW7,DNAAF10,KRAS,CHCHD2,NTAQ1,PMPCA,AUH,CALR,MTRF1,CALU,RIT1,MRPS26,SH3BP5L,GATD3,TACO1,PLEKHF2 |
| 3.929e-03 | -5.54 | CRYBG3 (crystallin beta-gamma domain containing 3) | protein interactions | 131544 | 63 | 28 | 19454 | 5460 |
DDX39A,MTCH2,ATG16L1,TOMM22,RPA2,RAB9A,RPA3,ZYX,FKBP8,FLOT1,TOMM20,KDM1A,YWHAH,RAB11A,SFN,MLF1,ZDHHC15,HAX1,LAMTOR1,KRT8,PHF21A,GSK3A,KTI12,AIFM1,TSSK1B,VIRMA,STX6,SSH3 |
| 3.929e-03 | -5.54 | NPHP4 (nephrocystin 4) | protein interactions | 261734 | 63 | 28 | 19454 | 5460 |
AIP,RHOJ,RPGRIP1L,RPP25L,TUBB,CACYBP,HSP90AB1,PPP1CC,FKBP4,DNAJC7,HSP90AA1,RPAP3,HSPA8,LCN1,JADE1,BAG2,TRIM37,TTC4,TRIM52,PTGES3,FTL,RAF1,TOP3B,NUDCD3,GKAP1,TUBB4B,PNMA2,PIH1D1 |
| 3.931e-03 | -5.54 | CNP (2',3'-cyclic nucleotide 3' phosphodiesterase) | protein interactions | 1267 | 182 | 68 | 19454 | 5460 |
MAP1B,HINT2,IGF1R,KRAS,UBE2A,B3GNT2,RAF1,TUBA1A,SOX2,TFCP2,SMARCB1,RND3,NUPR1,RAB35,HRAS,PHB1,ARF6,RHOH,CGAS,PRNP,EGLN3,DIRAS3,CAV1,LAMP2,DPP4,FAM174A,LAMP3,DDRGK1,RHOU,DVL2,RPA3,RAB29,PRKCB,HSPA8,SQSTM1,RAB9A,NUBP2,PMAIP1,AKAP1,UFL1,STAU1,FBXW7,STX7,ZDHHC17,BET1,CDC42,HPS6,MED23,RPA2,LMNA,FGFR1,CCNF,RHOJ,TUBB,UBB,NMI,ESR2,VIRMA,MYC,RAB2A,CIAO1,RAB11A,MRM2,CUL3,LAMTOR1,RHOB,ILK,UBE2H |
| 3.942e-03 | -5.54 | NADH dehydrogenase complex assembly | biological process | GO:0010257 | 55 | 26 | 18204 | 5365 |
NDUFA12,NDUFAF4,TIMM21,NDUFB7,NDUFA5,NDUFB8,NDUFA2,TMEM126A,NDUFS8,NDUFA1,TMEM126B,LYRM2,NDUFAF6,NDUFB10,NDUFAB1,NDUFC2,NDUFB5,NDUFB6,TAFAZZIN,COA1,NDUFS3,NDUFB4,BCS1L,NDUFS2,NDUFAF3,NDUFAF2 |
| 3.942e-03 | -5.54 | mitochondrial respiratory chain complex I assembly | biological process | GO:0032981 | 55 | 26 | 18204 | 5365 |
NDUFB10,NDUFAF6,NDUFAB1,NDUFA1,TMEM126B,NDUFS8,LYRM2,NDUFC2,NDUFA5,NDUFB7,NDUFA12,NDUFAF4,TIMM21,TMEM126A,NDUFA2,NDUFB8,NDUFB4,NDUFAF2,BCS1L,NDUFAF3,NDUFS2,TAFAZZIN,COA1,NDUFB5,NDUFB6,NDUFS3 |
| 3.957e-03 | -5.53 | IL1 and megakaryocytes in obesity | WikiPathways | WP2865 | 25 | 16 | 5310 | 1910 |
F2,TLR2,IL18,TIMP1,PIK3CA,HBEGF,NLRP3,MYD88,MMP9,NFKB1,CCR3,TLR1,IL1B,IFNG,CCL2,ICAM1 |
| 3.963e-03 | -5.53 | breast-other-papilloma | COSMIC cancer mutations | breast-other-papilloma | 30 | 16 | 16828 | 4835 |
FGFR1,PIK3CA,NTRK3,KIT,GNA11,MET,CTNNB1,TP53,AKT1,FBXW7,IDH2,GNAQ,HRAS,KRAS,PIK3R1,IDH1 |
| 3.963e-03 | -5.53 | lentigo_maligna | COSMIC cancer mutations | lentigo_maligna | 30 | 16 | 16828 | 4835 |
SF3B1,STK11,GNAQ,HRAS,KRAS,PTEN,TERT,PIK3CA,FGFR1,JAK2,AKT1,TP53,GNA11,MET,KIT,CTNNB1 |
| 3.973e-03 | -5.53 | PEPD (peptidase D) | protein interactions | 5184 | 83 | 35 | 19454 | 5460 |
THOC3,RAB1A,PSMG4,ERO1A,NUP50,RNF5,RPIA,HSPE1,STAU1,EIF4E,MVD,CAPN1,ARFGEF1,LDHAL6B,PAK2,RNF103,CTSA,SOD2,RARS1,CNDP2,MSN,HNRNPL,RAB1B,TXN,LDHA,PRNP,MAT2B,G6PD,BCCIP,MOV10,CUL2,LDHB,MMUT,SPP1,UBE2H |
| 3.973e-03 | -5.53 | ZNF217 (zinc finger protein 217) | protein interactions | 7764 | 83 | 35 | 19454 | 5460 |
PHF1,MCM6,TRIM37,GTF2I,KDM1A,DDX5,HINT1,HSPA8,EWSR1,CSNK1A1,PAX9,KLF3,CTBP1,CBX3,ZMYM3,KLF12,SAP30,EGR2,VIRMA,ESR2,HMG20A,SNRNP40,PHF21A,ZBTB18,ZMYM2,ELK3,CALU,RBBP8,AR,HDAC6,CSNK2A1,DNTTIP1,MYC,DYRK1B,HNF1B |
| 3.973e-03 | -5.53 | WDR70 (WD repeat domain 70) | protein interactions | 55100 | 83 | 35 | 19454 | 5460 |
CBX3,LMNA,RPA2,RBPJ,ATG16L1,GTF2H4,TOP3B,SUPT5H,CCT5,E2F4,KRAS,HUWE1,TSSC4,RPA3,PML,NUP50,DDX23,CHORDC1,CCT2,CALU,RIT1,TCEANC2,MYC,XPO1,GTF2E1,BTF3,HNRNPL,COPS7B,APEX1,DYRK1A,CCT7,SRPK2,SYT2,MRPS28,HP1BP3 |
| 3.980e-03 | -5.53 | S100A8 (S100 calcium binding protein A8) | protein interactions | 6279 | 179 | 67 | 19454 | 5460 |
UBASH3B,PTEN,ALB,RBBP4,GABPA,TUBB,LRIF1,ATP6AP2,VIRMA,MYC,CUL2,BAG3,DCAF4,COP1,DPH6,DDX39B,RPA3,SIRT7,KDM1A,RNF5,NF2,H2AC13,FBXW7,RNF11,IGSF21,AZGP1,ASB3,EFHD1,CDKN1A,ST7,CFTR,NUDT3,KLC2,RPL26L1,HEXIM1,MET,FABP5,S100A8,OCRL,RPL35A,PPIA,EPHB6,ERCC3,IFI16,EDEM1,PTDSS1,COPS5,ELOC,CSTA,BECN1,AGR2,SHC1,PPM1B,UPK1A,AGPAT1,USP15,ERG28,KRAS,RIGI,B3GNT2,RAF1,TP53,TUBA1A,ELF1,CCR1,APTX,RNF8 |
| 3.989e-03 | -5.52 | RBM4B (RNA binding motif protein 4B) | protein interactions | 83759 | 257 | 92 | 19454 | 5460 |
RBM34,IMP3,UBR7,FCF1,RPL15,NOC4L,HNRNPK,IMP4,PAK1IP1,CAPZA1,RIGI,MIRLET7C,MEPCE,NKRF,RPL3,MPHOSPH10,RPL10A,SPATS2L,MIRLET7G,TOP1,PRNP,FZR1,KLF1,SURF6,CDC5L,DKC1,MRPS9,ZNF770,MIR21,ZNF574,UTP15,RPLP0,RPL26L1,MIR34B,RPL4,WDR3,RPS15,BRIX1,AATF,NLE1,DDX46,MIRLET7I,STK24,RPF2,RPP25L,RSL24D1,PPP1R10,TENT2,RPP25,PELP1,CCNF,RBMX2,PHAX,RPL18,TXNRD1,RAF1,RPL29,MAK16,MIR9-2,RPL6,DDX50,IFI16,DDRGK1,NGDN,SNX2,CACYBP,MYEF2,RPL8,MIR214,STAU1,NOP53,HSCB,COIL,RPP14,SNRPA,STK26,FTSJ3,FYTTD1,NSA2,HNRNPC,NOP16,CUL3,MYC,OST4,ZNF668,ZCCHC7,RPL7L1,RPF1,MATR3,ESR2,MIRLET7D,MIRLET7B |
| 3.995e-03 | -5.52 | NUP35 (nucleoporin 35) | protein interactions | 129401 | 417 | 142 | 19454 | 5460 |
LMNA,GOLGA5,STOM,USE1,ZNF326,LEMD3,PCK2,SPR,TIMMDC1,SNRNP27,NTPCR,RBMS2,ST7,RBM22,TMEM209,TEX264,TXNDC17,CSTB,BANF1,FAM222B,THUMPD1,SPCS2,MAVS,DERL1,ANAPC4,NRP1,SORD,MAPRE1,GSTK1,CIAO1,CEP85,NTAQ1,MTPN,PPP1CC,TUFM,NONO,KCTD9,IRF2BP1,ROMO1,DYRK1A,PSPC1,PITPNB,QSER1,ODR4,TRIM24,UBE2I,ACAT1,NUPR1,FURIN,CMPK1,PREB,SERPINB9,NDUFA2,YTHDF2,NUP107,TMEM33,H2AC6,RNF133,TMX3,ESYT1,CDK12,TLE1,SLC25A46,DHRS7,COX5A,RAB23,ARL6IP5,TMPO,CDK9,NDUFB4,HSD17B11,FAM3C,NCOA5,NUP62,PGRMC1,PSMB3,BET1,OTULINL,TIMM13,GLRA2,EMC1,YTHDF1,PXMP2,TACR3,PEBP1,TXNL1,NMRAL1,NUP50,EP300,PSMA3,DDX5,ADK,RBM27,CYP1A1,ACO2,CREBBP,HNF1B,PSMA4,SMARCE1,TOMM40,MATR3,CHCHD3,ESR2,SRXN1,MIDEAS,RAN,SNRPD1,SEC61B,EZH2,GLE1,PDHA1,FAM136A,RBM12,HSDL2,KHDC4,RANBP1,CRTC2,NUP153,NUP37,HNRNPF,PSMA2,ZNF609,NUP42,TFG,PCNA,EWSR1,BCL9,FKBP4,DDX1,DDT,IFI16,CNOT2,CNOT8,ZNF207,PAIP1,GLRX,WIF1,NUP35,MYEF2,FUBP3,STX5,CYB5A |
| 3.996e-03 | -5.52 | MARK3 (microtubule affinity regulating kinase 3) | protein interactions | 4140 | 235 | 85 | 19454 | 5460 |
HNRNPL,ARF6,RHOH,MITF,STX6,TMCC2,LMAN1,PRKCQ,DIRAS3,CAV1,MRPS23,RAB35,HRAS,ALYREF,PPP2CB,GJA1,RAC2,RHOG,DDX1,STYK1,YWHAB,LAMP2,YWHAG,YWHAH,LAMP3,G3BP1,KRAS,THRAP3,CAPZA1,PTGES3,FLOT1,POLDIP3,HNRNPDL,TRIP4,GARRE1,TCEA2,LSM14A,GPSM3,NTRK2,RTCB,STIM1,PNMA2,RND3,TBC1D4,RAF1,PPP2R1A,SOX2,KIF2A,DAPK1,RHOJ,MANSC1,DYNLL1,APEX1,ESR2,CTNNA1,TMEM74,GSK3A,LAMTOR1,YWHAZ,RHOB,TEX19,UBE2H,RAB2A,RAB11A,SFN,FBXO7,DNAJC5,TTR,STX7,G3BP2,RHOU,DVL2,RPA3,PPM1G,HDAC5,RAB9A,RAB5A,RPA2,FGFR1,CPSF4,CLDN4,CDC42,AGO1,RND2,FGF13 |
| 3.996e-03 | -5.52 | DCAF1 (DDB1 and CUL4 associated factor 1) | protein interactions | 9730 | 210 | 77 | 19454 | 5460 |
H1-1,RIT1,COP1,NCKIPSD,MYO6,FTSJ3,ATP5F1A,SAMHD1,CFAP20,CUL3,RPL7A,MYC,COPS7A,RPL19,RPL10,VIRMA,DYNLL1,RPL35,RPL13A,TP53TG5,MACROH2A1,RPS9,AP2M1,VPS72,RAG1,UBE2M,MFAP1,DYRK2,WWP1,RPA2,TIMM13,RPL27A,HSPA5,RPL4,DUSP26,UBE2D3,NF2,HDAC3,HSCB,TERT,SIRT7,DVL2,TOPBP1,SMG9,POU5F1,COPS5,RPL6,TCEANC2,MOV10,HSP90AB1,EGLN3,PTP4A3,RPL7,COPS7B,DCUN1D1,COPS2,MAP1LC3A,RCHY1,SRP14,RPL18,NFE2L2,RPL15,PPP2R1A,SOX2,AURKAIP1,TP53,ZNF263,ANP32A,COPS4,KRAS,NEDD8,H3C1,RPS24,RPL23A,MRFAP1,RPL3,TFPT |
| 3.996e-03 | -5.52 | ABI1 (abl interactor 1) | protein interactions | 10006 | 210 | 77 | 19454 | 5460 |
CTTN,TUBA1B,CCNF,ESR2,NCKAP1,HOMER1,TUBB,ACTB,TTC23,SLC1A3,BTF3,EPS8,AKT1,FGFR1OP2,CDC123,THOC6,NTRK3,PDCD4,CCHCR1,IVNS1ABP,RHOB,YWHAZ,CCDC22,LAMTOR1,PPIH,RAB9A,PSMA3,HSPA8,RPA3,BAP1,WASF3,SKP1,STX7,CYFIP2,TRA2B,FBXL19,ATG16L1,SLC25A3,CSNK1G3,FGFR1,RPA2,PAK2,RAC2,CORO1C,HOMER3,HRAS,DNM2,RAB35,SPTAN1,CCAR2,ZNF511,YWHAH,YWHAG,WWP2,PIK3R1,HSPB1,CBL,NCK1,SOS2,MRFAP1,PRPSAP1,SLC25A11,MRFAP1L1,SLC25A5,PRPS1,ENKD1,WASL,HNRNPK,AKAP12,KRAS,PPP2R1A,ARHGAP12,KIAA0408,DHX38,CMPK1,CCR1,TUBB4B |
| 4.009e-03 | -5.52 | MRE11 (MRE11 homolog, double strand break repair nuclease) | protein interactions | 4361 | 276 | 98 | 19454 | 5460 |
RAF1,ZNF263,FEN1,NLRP2,RNF126,EZH2,SKA3,RTCB,HNRNPA2B1,ABCF1,UBE2A,DHX16,PELI1,RAB32,DDX1,POU5F1,EED,NKX3-1,EGLN3,SUMO2,SEC62,PPARG,EP300,HSPA8,BIRC2,EXD2,XRCC5,RFC4,STAU1,UFL1,CFAP161,CUL3,SCG3,MYC,FAM219A,HSP90AA1,BRCA1,FBXW11,RBBP8,ESR2,BMP1,DYNLL1,RBBP4,TSN,TRIM29,H2AX,TP53,KBTBD4,RNF8,NUPR1,ILF2,NECAP1,CHAMP1,SEMG2,DHX9,MDC1,MSH6,ZNF365,HUWE1,HDAC6,ERCC3,TSNAX,FOXP1,TDRD7,CDC5L,MDM2,TMPO,PRNP,EIF2B2,CCNA2,SUMO1,TPT1,RPL26L1,HSP90B1,EIF2B3,RPA2,LMNA,PPIH,SIRT7,NBN,RPA3,DVL2,RPL27,BAP1,HMGB1,FBXW7,NUCKS1,USP14,AR,CIAO1,TXNIP,SPOP,RPS20,RTRAF,CCNF,DCLRE1C,DUSP10,NDN |
| 4.028e-03 | -5.51 | EIF4E (eukaryotic translation initiation factor 4E) | protein interactions | 1977 | 176 | 66 | 19454 | 5460 |
RAB1A,HSPD1,PABPC1,LSM14A,CD83,PRDM4,DYNC1I1,G3BP1,KRAS,EIF4EBP2,EIF3E,PRDX4,HNRNPDL,YTHDF2,OTUD6B,SRP72,PSMC3,OTX2,EIF4E2,RPS16,RPS27L,CDK9,RBM42,NCBP2,EIF3D,DDRGK1,CTNNB1,UBFD1,AHSA1,DRG1,EMX2,DICER1,BAP1,PML,PRKCB,BIRC2,HSPB2,TRIM22,RNF113A,WDR3,STAU1,PSMC1,EIF4E,POLA2,AATF,MAPKAPK5,CAPN1,PRKCA,EIF4B,PIH1D1,EIF4EBP3,STUB1,PSPC1,METAP2,EIF3K,TRIM27,PTEN,EIF4H,EIF4A2,PSMD6,ESR2,CSK,PSMA4,EIF3G,UBE2H,RIT1 |
| 4.028e-03 | -5.51 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043280 | 116 | 48 | 18204 | 5365 |
TNF,TNFSF10,ACVR1C,MUL1,BOK,SMAD3,BAK1,CLEC7A,MYC,BAX,RPS3,MIR15A,EGLN3,DAPK1,NLRP1,FAM162A,SYK,HMGB1,PDCD5,BCL10,HSPD1,AIFM1,TNFSF15,S100A8,NKX3-1,FASLG,KHDC1,PYCARD,JAK2,BCL2L1,BCL2A1,CRADD,PMAIP1,NLRP2,DAP,BAD,HTRA2,MCL1,ANP32B,FAS,IFT57,NLRP3,FIS1,PPARG,ARL6IP5,HSPE1,RPS27L,CTSD |
| 4.035e-03 | -5.51 | H3C1 (H3 clustered histone 1) | protein interactions | 8350 | 719 | 234 | 19454 | 5460 |
RSBN1L,MRPS26,SKIC8,KDM2A,HNRNPA1,HMGA1,CLPX,MRPS35,LRWD1,BUD31,HP1BP3,COPS2,RPL8,RBPJ,EZH2,RPL29,GTF2E2,ANP32A,FEN1,UBE2A,MCM6,GTF3C3,FLOT1,SSRP1,RFC3,PCGF6,ANP32B,RFC2,RAD21,RBBP7,LASP1,CBX7,ASF1A,PCNA,MORC2,AKT2,SETD7,YWHAZ,IRF1,RFC5,MCM4,ACO2,HNF1B,RAB11A,MAD2L1,RPL19,RBBP4,RFXAP,RPS9,ZMAT2,S100A6,PARP2,RTF2,USP39,ADNP,PPP1CB,H1-5,CMAS,CFDP1,JADE1,EMG1,HADHA,BRD3,EID1,KIAA1143,HDAC6,GTF2E1,ZMYND11,SUV39H1,MOV10,SPATS2L,CDK9,MRPS23,MAPRE2,TOP1,H2AZ1,RCHY1,KRR1,SRP72,RAD23B,DMAP1,LBR,UBR7,MTA3,MDC1,SNRPG,MSH6,ANAPC11,CTNNBL1,VRK1,PQBP1,CDC73,RACGAP1,DNAJC8,CDC16,VIRMA,DEK,MAGOHB,RPL13A,TRIM24,PELP1,CDAN1,MACROH2A2,MRPS34,LMNA,EDF1,PIAS1,MBD3,POLDIP2,BRIX1,HMGB1,PRKCB,ANAPC16,PPM1G,HELLS,SIRT7,CSTB,SPHK2,CDC23,YWHAB,DNTTIP1,YWHAG,CTNNB1,CENPW,BAZ1B,RPL6,EED,RFX5,SIN3A,ZRANB2,MTA2,HDAC11,PDHA1,TOP3B,DHX38,HMGN4,CYP1B1,RPL31,TOP2B,H1-1,FTSJ3,H1-10,CHTOP,BTF3,RPL39,THAP7,CREBBP,HNRNPAB,LRIF1,CBX5,ESR2,USP38,TRIM29,PRMT5,SMU1,ZMYM2,GTF2F1,GTF2F2,MIDEAS,ADSS2,ELK4,MRPL12,PSMB3,GNB4,MRPS7,STAU1,SF3B1,HSPA8,HDAC5,EP300,HIRA,RFC4,SNRPA,FLYWCH2,XRCC5,TAF9,RPL10A,SMCHD1,SNRNP70,H2AC4,PPM1D,API5,DPP4,USP3,MBD5,TMPO,BRMS1L,SHPRH,MRPS9,RPL32,TAF2,NUPR1,CBX3,CHAMP1,IK,NFE2L2,RBM34,H2AX,ZMYM4,SRFBP1,CENPM,PHF1,MEPCE,H3C1,RPL3,MECP2,FBXO44,SMARCA5,CSTF3,CDC20,BCCIP,DYRK1A,HPF1,MACROH2A1,CREB1,UBN1,TMA7,LIG3,PRKCA,UBE2M,LEMD3,RAG1,RPA2,GTF3C4,GRPEL1,WDR55,HDAC3,UBE2K,KDM1A,H2AC13,CWF19L1,POLD2,NBN,BANF1 |
| 4.036e-03 | -5.51 | regulation of signaling receptor activity | biological process | GO:0010469 | 99 | 42 | 18204 | 5365 |
ERRFI1,BUD31,CBL,PATE4,NLGN2,HFE,CLEC12B,SOCS5,CAPN1,ADRB2,GREM1,DLG4,LILRB4,LYNX1,PPARA,OPRM1,CACNG3,FCGR2B,PPARG,NOG,HDAC6,CCR2,FBXW7,NETO1,SOCS4,IL10,PCSK9,NLGN1,IFNG,JAK2,TAFA1,TNF,CCL2,TSG101,PRRT1,DLGAP4,GREM2,CAV3,DAPK1,CNRIP1,RAMP3,CRHBP |
| 4.047e-03 | -5.51 | hormone biosynthetic process | biological process | GO:0042446 | 42 | 21 | 18204 | 5365 |
HFE,HSD17B11,TSPO,CYP11B2,DIO3,CYP17A1,LHB,CHST9,ASMT,DHRS11,HSD17B3,SRD5A3,CYP21A2,CYP11B1,DIO2,HSD17B8,HSD17B1,DIO1,AKR1B1,AANAT,HSD17B6 |
| 4.070e-03 | -5.50 | EIF5A2 (eukaryotic translation initiation factor 5A2) | protein interactions | 56648 | 52 | 24 | 19454 | 5460 |
HERC3,EWSR1,RAB30,METTL14,SDCBP,EZH2,GINS4,PIH1D1,DOHH,HEXIM1,FBP1,CLEC2B,TAGLN2,CCNF,OPTN,FOLR1,AGR2,NIF3L1,NAB2,CDC23,CUL3,DHPS,MYC,PPIB |
| 4.070e-03 | -5.50 | MVB12A (multivesicular body subunit 12A) | protein interactions | 93343 | 52 | 24 | 19454 | 5460 |
VPS28,APEX1,CCAR1,MANSC1,PPP1R27,CEP41,KRAS,CERS2,ARFIP1,PTEN,TSG101,PSME2,OXTR,HGS,CDK5R1,BICD2,SMCHD1,XPO1,CD2AP,CENPM,TAS2R7,CIDEB,AUH,AKR7A2 |
| 4.070e-03 | -5.50 | CCR2 (C-C motif chemokine receptor 2) | protein interactions | 729230 | 52 | 24 | 19454 | 5460 |
TMEM199,CDIP1,SLC41A3,CCL11,CD81,HMOX2,RHOG,SLC2A1,NTNG2,SCG5,ARL6IP5,NDFIP1,CACYBP,JAK2,EMC10,NOTCH2,SUMO1,CD59,CCR5,TSPAN7,TPST1,CCL2,SVOP,CCL8 |
| 4.070e-03 | -5.50 | TRAPPC6A (trafficking protein particle complex subunit 6A) | protein interactions | 79090 | 52 | 24 | 19454 | 5460 |
TRAPPC6B,SMUG1,TRIM35,CAVIN2,TAX1BP1,TRAPPC3,TRAPPC10,SERTAD3,TRAPPC2L,HSPB8,GORASP2,TTC23,PFDN5,GINS3,PAX6,MYOZ3,TRAPPC1,SF3B5,TRAPPC3L,TRAPPC6A,WTAP,CRYAB,CTDSP1,CD2BP2 |
| 4.070e-03 | -5.50 | RAP2C (RAP2C, member of RAS oncogene family) | protein interactions | 57826 | 52 | 24 | 19454 | 5460 |
RPS10,KRAS,RAB1B,ADRB2,TCP1,CCT7,ESR2,HRAS,RAB1A,RPA3,CCT8,RABGGTB,RAC2,PMAIP1,RAP2A,SPCS3,CCT2,RPA2,RHOB,GRM2,PDCL,TP53,DDX39A,FTH1 |
| 4.072e-03 | -5.50 | Formation of the Early Elongation Complex | REACTOME pathways | R-HSA-113418 | 35 | 19 | 10285 | 3229 |
CDK7,MNAT1,ERCC3,SUPT5H,POLR2B,NCBP2,POLR2F,CCNH,POLR2C,POLR2G,SUPT4H1,GTF2H4,GTF2F2,GTF2F1,GTF2H2,POLR2D,GTF2H5,POLR2L,POLR2I |
| 4.072e-03 | -5.50 | TRAF6 mediated IRF7 activation | REACTOME pathways | R-HSA-933541 | 35 | 19 | 10285 | 3229 |
IFNA2,TRAF2,IRF7,TANK,SIKE1,MAVS,IFNA13,IRF1,TRAF6,IFIH1,RIGI,IRF3,IFNA10,CREBBP,EP300,IRF2,TBK1,IFNB1,MYD88 |
| 4.072e-03 | -5.50 | Formation of the HIV-1 Early Elongation Complex | REACTOME pathways | R-HSA-167158 | 35 | 19 | 10285 | 3229 |
POLR2F,GTF2H4,GTF2F2,POLR2G,CCNH,POLR2C,SUPT4H1,POLR2D,GTF2H5,POLR2I,POLR2L,GTF2H2,GTF2F1,CDK7,MNAT1,POLR2B,NCBP2,ERCC3,SUPT5H |
| 4.075e-03 | -5.50 | TEX264 (testis expressed 264, ER-phagy receptor) | protein interactions | 51368 | 173 | 65 | 19454 | 5460 |
FKBP8,GJB1,RAB3B,SEMA4C,TMT1A,STIM1,TMEM31,RPN1,NGB,GABARAPL1,DNAJC25,MAP1LC3B,CCDC47,PREB,CSNK1E,MTCH2,LRRC61,LMAN1,TMPO,NUP35,DNAJC1,MAP1LC3A,GJA1,HSD17B11,LHFPL4,SPINT2,PTPN1,RAB35,NKX3-1,TMEM30A,OSBPL8,TM4SF18,ESYT1,LAMP2,RAB5C,EDEM1,SLC25A46,ICAM2,PXMP2,STX7,GABARAP,SYVN1,RAB5A,RAB9A,SLC35F2,DERL1,CSNK1A1,LMNA,SSR1,RND2,OTULINL,SEC62,GABARAPL2,ST7,SEC63,APEX1,STAT1,RMDN3,SEC61B,NTRK3,SNX14,LMNB1,HMOX2,OPRM1,RAB11A |
| 4.075e-03 | -5.50 | AKAP8 (A-kinase anchoring protein 8) | protein interactions | 10270 | 173 | 65 | 19454 | 5460 |
SSRP1,THRAP3,TRIM37,RUVBL1,EWSR1,RUVBL2,TUBB4B,EZH2,HDAC11,RAF1,E2F4,LRWD1,CDC5L,NUP35,FZR1,CAND1,TOP1,ARL4D,TES,EEF1B2,FBXO32,YWHAB,HSPB1,SNRNP70,YWHAG,HNRNPA1,COPS5,CSNK2A1,YWHAH,ZMYND11,FAM20C,FOXC2,CCND3,HSCB,STAU1,DDX5,RNF113A,EP300,BAP1,SNRPA,RPA3,FOXS1,RPA2,CCND1,SMURF1,ESR2,VIRMA,MATR3,SNRNP40,FOXP3,LMBR1L,CCNF,ILK,UBE2H,FBXW11,YWHAZ,DCAF4,BRCA1,RC3H2,PRKACB,SNRPB,MYC,APOBEC3B,FOXA3,CUL3 |
| 4.083e-03 | -5.50 | manganese ion binding | molecular function | GO:0030145 | 65 | 30 | 18094 | 5411 |
NUDT16,FEN1,LARGE1,NUDT3,XPNPEP1,PAPOLA,MGAT1,XXYLT1,GALNT4,MPPED2,ARG2,B4GALT1,GALNT1,GALNT2,SOD2,PPM1K,EXD2,DYRK2,PCK2,PPM1B,MGAT5B,ADCY2,NUDT7,FAM20C,B4GALT7,ADPRM,LAP3,DCP2,EXTL2,PPM1M |
| 4.092e-03 | -5.50 | positive regulation of activated T cell proliferation | biological process | GO:0042104 | 27 | 15 | 18204 | 5365 |
IL23A,GPAM,IL2,MIR30B,MIR21,AGER,PYCARD,RPS3,IGF1,IL2RA,HMGB1,EPO,IL18,PPP3CA,IL12B |
| 4.092e-03 | -5.50 | eosinophil migration | biological process | GO:0072677 | 27 | 15 | 18204 | 5365 |
CCL8,CCL18,CCL11,CCL4L1,CCL24,CCL2,CCL3,CCL5,LGALS3,CCL1,CCL23,XCL1,SCG2,CCL25,CX3CL1 |
| 4.092e-03 | -5.50 | postsynaptic specialization organization | biological process | GO:0099084 | 27 | 15 | 18204 | 5365 |
PTEN,OPHN1,LRRC4,NLGN1,HSPA8,NTNG2,C1QL3,NLGN2,TMEM108,ARF6,CRKL,NPTX1,DLG1,CNTNAP1,C1QL2 |
| 4.092e-03 | -5.50 | cellular response to gamma radiation | biological process | GO:0071480 | 27 | 15 | 18204 | 5365 |
BCL2L1,ELK1,MDM2,ZMPSTE24,EGR1,GTF2H5,CDKN1A,KDM1A,TP53,H2AX,XRCC5,HRAS,RPL26,MIR21,CRYAB |
| 4.098e-03 | -5.50 | BRD3 (bromodomain containing 3) | protein interactions | 8019 | 479 | 161 | 19454 | 5460 |
POLB,SPP1,SMCHD1,NOS1AP,AKAP8L,TAF9,ERCC3,SETD5,CSNK2A1,MPG,RPL35A,TOP1,ABHD8,NKAP,ATP5PD,KMT5B,AKAP17A,TMPO,SURF6,PTPN1,CTDSPL2,H2AZ1,PWP2,DMAP1,CBX3,UAP1,CHAMP1,CIBAR1,TOPORS,TAF2,MTA3,ATP5PB,TP53,MAP1LC3B,H2AX,BCS1L,CAMKV,H3C1,VRK1,SCML1,MEPCE,MDC1,RIGI,SNIP1,TFPT,ATP5PF,MECP2,SPOP,PIP4K2C,AP2A1,UBE2H,CALU,CAP2,SMARCA5,MORF4L1,ZNF687,AR,IFI6,SCML2,SRPK2,VIRMA,DEK,ZNF330,LIG3,TUBA1B,CSNK2B,MACROH2A1,RPS12,LMNA,E2F6,MACROH2A2,GTF2H4,SAP30BP,NFYB,SUMO1,MED30,CDK7,EIF5B,RPL4,MBD3,BCL6,SS18,HELLS,BANF1,PNO1,ANAPC16,MED4,RSBN1L,BAZ1B,TAF7,CDC26,INO80E,BCL7C,TRA2A,ZNF740,NOP58,LYAR,LRWD1,HMG20A,THOC2,SRSF1,HP1BP3,BRD9,FAHD1,EZH2,NFKBIL1,CAAP1,SMARCB1,TAF10,ZNF263,DHX38,H1-3,KIF2A,ZNF592,HMGN4,GTF3C3,SSRP1,RFC2,RPL31,TOP2B,ARGLU1,ABCF1,RUVBL2,INO80C,BAG2,MED10,FTSJ3,H2AZ2,CHTOP,RPS26,PAXX,THOC6,MYC,PROX1,SMARCE1,RFC5,FBXO22,RPL7L1,CBX5,TAF11,TNPO3,APEX1,ZHX3,FAU,POLR3B,GTF2F2,USP39,MED23,ADNP,MFAP1,ACTL6A,ZNF362,MED11,TSR3,TRA2B,SAP18,COIL,SKP1,RFC4,EMG1,CCDC86 |
| 4.114e-03 | -5.49 | negative regulation of mitotic cell cycle phase transition | biological process | GO:1901991 | 183 | 71 | 18204 | 5365 |
CRLF3,MDM2,DTL,ZNF207,MIR133B,CDK2AP2,TP53,IER3,SPC24,FBXO31,RPA2,MIR15A,VPS4A,FZR1,CDC20,FAM107A,RINT1,CDK1,TOPBP1,NUF2,NOP53,BTN2A2,KLF4,RPL26,JADE1,CTDSP2,FBXO7,MIR638,MIR29C,MIR137,PTEN,RBBP8,CCL2,MAD2L1,MAD2L2,RAD21,NABP1,CDKN1A,NDC80,PML,CACNB4,MIR16-1,ZNF655,PRMT2,BABAM1,CRADD,CDK5RAP3,MIR195,TPRA1,DCUN1D3,IK,RB1,EZH2,MIR29A,CDKN1B,BUB3,MIR193A,KLHL22,BRCA1,RGCC,ACVR1,NAE1,GPNMB,CHMP4C,CTDSP1,CCND1,PSMG2,NBN,RPS27L,DLG1,CDC73 |
| 4.121e-03 | -5.49 | PWP1 (PWP1 homolog, endonuclein) | protein interactions | 11137 | 170 | 64 | 19454 | 5460 |
FZR1,CAND1,CGAS,TOP1,ZBTB2,KLF9,SSBP1,TUBG1,SNRNP70,DRG1,LHX2,RPL23,IRF9,DPP4,IFI16,COPS5,EIF3D,DDRGK1,KRAS,NEDD8,H3C1,FN3KRP,RPL28,TCOF1,TRIM11,RBM34,HBP1,NUPR1,RAF1,TP53,SOX2,ELF1,RPL15,PRDX2,DAPK1,TXNDC12,SMURF1,ESR2,SRPK2,PELO,ELK3,PSKH1,FAS,FTSJ3,RC3H2,RIT1,UBE2H,MYC,NFYA,CUL3,RPL7A,PPP1CC,HSCB,UFL1,STAU1,FBXW7,HSPA5,SIRT7,SQSTM1,RNF113A,EP300,ATG16L1,KLF12,CDK7 |
| 4.124e-03 | -5.49 | protein-disulfide reductase activity | molecular function | GO:0015035 | 34 | 18 | 18094 | 5411 |
CCS,TXNRD3,TXNRD1,PGK1,TXNL1,TXN,ERO1A,TXNRD2,TXNDC12,DNAJC10,PDIA3,TMX3,GLRX2,CHCHD4,SELENOT,TXNDC17,PDIA6,PDIA2 |
| 4.124e-03 | -5.49 | pattern recognition receptor activity | molecular function | GO:0038187 | 34 | 18 | 18094 | 5411 |
TLR9,NLRP1,TLR5,TLR7,IFIH1,CD36,TLR2,TLR8,NLRP6,CLEC7A,LY96,RIGI,CD14,DHX16,TLR3,CLEC6A,TRIM5,TLR4 |
| 4.129e-03 | -5.49 | TDG (thymine DNA glycosylase) | protein interactions | 6996 | 66 | 29 | 19454 | 5460 |
VDR,TP53,SUMO1,JUN,MX1,RAD1,RAD23B,DDX39B,SNIP1,PML,PCNA,EP300,TTC4,ROCK2,TFG,CREBBP,MYC,NFYA,AR,SMAD4,DTL,PDAP1,UBE2I,PGR,SUMO2,SNX2,SUMO3,JUNB,APEX1 |
| 4.129e-03 | -5.49 | NFATC2IP (nuclear factor of activated T cells 2 interacting protein) | protein interactions | 84901 | 66 | 29 | 19454 | 5460 |
RPA3,FOS,DNAL4,TCEA1,GTF2I,COIL,ZDHHC17,ZNHIT1,E2F4,TRAF2,LMNA,CBX3,DMAP1,SMNDC1,VPS72,TMA7,ZNF330,ZMAT2,SUMO2,SNRNP40,TRAF1,MOV10,PYCARD,NTAQ1,RHEB,RPL26,AR,TRAF6,TSNAX |
| 4.129e-03 | -5.49 | EMC6 (ER membrane protein complex subunit 6) | protein interactions | 83460 | 66 | 29 | 19454 | 5460 |
LDLR,LMBR1L,PLAC9,ELOVL4,TLCD4,ESR2,TMEM237,MMD,GOLPH3L,FAM241A,CREB3,EMC4,PDZK1IP1,MFSD14B,REEP6,OSBPL8,EMC2,TSPAN15,SLC7A1,EMC8,EMC1,LPAR1,OTULINL,DNAJC25,ST7,CCDC47,EMC10,TMEM14B,EMC9 |
| 4.129e-03 | -5.49 | TANGO6 (transport and golgi organization 6 homolog) | protein interactions | 79613 | 66 | 29 | 19454 | 5460 |
ATG7,UBXN6,RIT1,DNAJC7,PHF21A,GPN2,PPM1M,CIB2,UBE2S,VIRMA,POLR2B,EGLN3,RANGRF,MMP28,CAPZA2,MAGEA4,UBE3A,BAG2,GALNT12,RPAP3,HSPA8,RUVBL2,P4HA2,TFPT,RUVBL1,CDK20,DNAAF10,KRAS,KDM1A |
| 4.129e-03 | -5.49 | KATNA1 (katanin catalytic subunit A1) | protein interactions | 11104 | 66 | 29 | 19454 | 5460 |
CUL3,CAMSAP2,UBE2H,PFDN4,PFDN2,SSX2IP,HSP90AA1,LACRT,CCT2,SLC30A7,STUB1,INPP5K,SRPRA,CCT7,CCT5,CAPN1,PAFAH1B1,SPTBN1,AKR7A2,ACACA,DYRK2,PNMA2,CLK1,LDLRAD4,CLU,ASB3,PFDN1,SRPRB,SRSF2 |
| 4.129e-03 | -5.49 | RGPD8 (RANBP2 like and GRIP domain containing 8) | protein interactions | 727851 | 66 | 29 | 19454 | 5460 |
MIA2,NUP50,RPS24,KPNA2,NUP107,NUP153,MLLT6,NUP62,FAM136A,DISC1,IER2,ANAPC2,PSMC5,RAN,TRAF3IP3,PTPN1,INSYN1,XPO1,HSPB8,BTF3,CUL3,UBXN6,IFI16,FGFR1OP2,TSNAX,RIT1,PSMD10,BICD2,CCDC92 |
| 4.129e-03 | -5.49 | COLEC12 (collectin subfamily member 12) | protein interactions | 81035 | 66 | 29 | 19454 | 5460 |
TMEM59,ATG16L1,TMEM126A,RAB4A,ZC4H2,MMP9,HSPA8,TSPAN15,STX7,LPAR1,EXOC1,FBXO7,LAMP3,RAB11A,RAB5C,LAMP2,RAB2A,CGRRF1,LGALS8,FXYD6,LAMTOR1,SEC61B,AP2M1,CD79B,TLR1,HOMER1,LGALS3,PRNP,C1QTNF1 |
| 4.139e-03 | -5.49 | human chr17q12 | chromosome location | human chr17q12 | 121 | 40 | 26134 | 5823 |
AATF,ZNHIT3,DUSP14,HNF1B,SPMAP1,RDM1,TCAP,CCL5,NEUROD2,RPL19,PPP1R1B,CCL1,CCL2,EPOP,PCGF2,CCL8,CCL18,RASL10B,CDK12,HEATR9,LASP1,FNDC8,MIEN1,MMP28,PIGW,PGAP3,CCL3,ACACA,LYZL6,MIR378J,CCL4L1,CCL23,RPL23,SYNRG,NLE1,PSMB3,CCL11,MLLT6,LIG3,DHRS11 |
| 4.141e-03 | -5.49 | LASP1 (LIM and SH3 protein 1) | protein interactions | 3927 | 229 | 83 | 19454 | 5460 |
SLC25A44,CKS1B,ARFGAP1,RAF1,CSTF2T,THAP1,GUCD1,EZH2,NUPR1,HGS,VAC14,BHLHE40,ZYX,PLSCR1,FHL3,FAM168A,HSPE1,CRYBA2,H3C1,HNRNPF,SLC25A32,TFG,KRTAP12-4,MDFI,API5,GAS8,HDAC6,COPS5,CD81,HSPB1,USP15,MAP4,CDK12,HAX1,DOK6,TES,PRNP,SPTAN1,RPL35A,CDK9,ATG16L1,CFTR,LMO4,CDK7,SNRNP27,RPA2,RDH12,EIF4B,SCLT1,PML,FAM168B,RPA3,ACTMAP,EP300,PSMA3,HSPA8,PGK1,STAU1,YTHDF1,FXR2,G3BP2,ZDHHC17,PIAS1,SFN,CUL3,MYC,NFYA,MGAT5B,BTF3,CRYBA1,BICD2,FYTTD1,BAHD1,ILK,POU1F1,ATP1A1,CCNF,UFSP1,TRIM27,ACTB,YES1,STAT1,THAP8 |
| 4.144e-03 | -5.49 | regulation of epithelial cell apoptotic process | biological process | GO:1904035 | 119 | 49 | 18204 | 5365 |
MIR125A,JAK2,NFE2L2,CCL2,RB1,CD248,TERT,EIF2S1,IL4,RGCC,MIR30E,TIA1,CDKN1B,SFRP4,MIR30B,MIR375,IL10,BOK,MIR24-1,MIR101-1,STK4,MIR675,ICAM1,TNF,MIR106B,IL13,NUPR1,MIR15A,IL6,IGF1R,MIR126,TNFAIP3,PDCD4,BAX,NDNF,ANGPT1,CD40,MIR132,SAV1,SCG2,MIR495,MIR182,CD40LG,FASLG,HAND2,KRIT1,PPARA,MIR590,SEMA5A |
| 4.158e-03 | -5.48 | FMNL1 (formin like 1) | protein interactions | 752 | 89 | 37 | 19454 | 5460 |
RHOH,KCTD10,RHOJ,ATP5F1B,TRIM54,HMG20A,SRPK2,PPP1R10,TMPO,CHCHD3,RAC2,CORO1C,RHOB,RHOG,RAB11A,TUFM,TOMM40,TIA1,PHB2,VDAC1,HSPA5,SSRP1,XRCC5,ABCF1,ZNF787,RHOU,PPP1R12A,CWF19L1,STOM,RAB4A,HSP90B1,NUFIP2,MTCH2,ATG16L1,CDC42,ACTN4,RND2 |
| 4.158e-03 | -5.48 | RXFP1 (relaxin family peptide receptor 1) | protein interactions | 59350 | 89 | 37 | 19454 | 5460 |
BTN2A2,CGRRF1,SMPD2,KCNJ8,DHRS7,CSK,RLN3,RETSAT,TMEM237,SRPK2,CNPY4,DNAJB9,LRP12,GJA1,ADCY3,FAM8A1,EPHX1,RAB6B,TMEM94,ST7,CYB5R1,SLC29A1,CNPY3,ABHD6,SYNGR2,RLN2,ABCC5,TMUB1,CLDND1,UBE3A,HERC3,ATP2B4,LRP10,ABCB9,TMX2,FSTL1,LRRC8D |
| 4.158e-03 | -5.48 | FASTKD1 (FAST kinase domains 1) | protein interactions | 79675 | 89 | 37 | 19454 | 5460 |
FASTKD5,TRIM63,CD80,NPTN,LRRN4CL,GFM1,COX8A,VIPR1,AMACR,CXCR4,STK16,AQP3,PDHA1,KLRD1,HCST,LPAR6,MGARP,CLEC2B,NPY2R,CHRM3,FAM234A,APLNR,RAMP3,PRNP,IL2RA,STARD3NL,CCDC90B,SSBP1,CCNF,AIFM1,SCN2B,SLC2A1,LAMP3,P2RY10,GPR17,FAM174A,OPRM1 |
| 4.158e-03 | -5.48 | ITGA2 (integrin subunit alpha 2) | protein interactions | 3673 | 89 | 37 | 19454 | 5460 |
OTULINL,CBLN4,CFTR,EDDM3B,RND3,CD46,SFTPC,PICK1,ITGA2,RAB5A,KRAS,CLEC12B,SCGB1D1,LAMP3,PDIA3,RAB2A,CFC1,RAB11A,COL1A2,LAMTOR1,RHOG,TAFAZZIN,LGALS8,RHOB,DNASE1L1,ALB,RAB35,HRAS,DIRAS3,SH3BGRL,CAV1,VIRMA,RABIF,ARF6,ALCAM,PSMD4,LGALS3 |
| 4.160e-03 | -5.48 | response to steroid hormone | biological process | GO:0048545 | 285 | 105 | 18204 | 5365 |
MGARP,YWHAH,PTGES3,COMT,SST,UGT1A1,ATP5F1A,TRIP4,SRC,GHR,HSPA8,KLF9,ERRFI1,PHB2,FIBIN,TFPI,RXRG,PPARA,GNRH1,MDM2,TAF7,PIK3CA,UBE3A,RNF14,FBXO32,EIF4E,PTGER2,IGF1R,IL6,DDX5,BGLAP,PADI2,NR2E1,RAN,TSPO,PCK2,CDO1,RWDD1,TACR1,PGR,ATP1A3,CLDN1,SMYD3,ABHD2,CAV1,PTGDS,EPO,RBFOX2,ALPL,USP8,TXNIP,UCN,ESR2,MSTN,FAM107A,CLDN4,AIFM1,SPP1,TGFB3,NKX3-1,HDAC6,DDIT4,CST11,ADTRP,FKRP,STC1,UCP2,RBBP7,ADIPOQ,TNF,TGFB2,IL10,CALR,GJB2,UBE2L3,PAQR8,AANAT,PCNA,ATP1A1,OXTR,PHB1,RPL27,CD38,NEFL,TADA3,TLR2,CYP1B1,IL22,FKBP4,VPS54,TRIM63,AR,ATP1A2,OR51E2,FOS,JAK2,GAD2,WBP2,CDKN1A,FOSL2,GSK3A,GPR83,EGLN2,TYMS,IDH1 |
| 4.164e-03 | -5.48 | GDHRDH | prints domains | PR00081 | 53 | 25 | 5227 | 1528 |
DHRS3,SDR16C5,RDH11,HSD17B8,HSD17B3,DHRS7,HSD17B10,DHRS1,HSDL1,CBR3,HSD17B1,HSDL2,HSD17B6,DHRS4,DHRS11,SPR,RDH12,DECR2,HSD17B11,DHRS13,KDSR,HSD11B1,CBR4,RDH10,DHRS7B |
| 4.191e-03 | -5.47 | soft_tissue-blood_vessel-haemangioma | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma | 18 | 11 | 16828 | 4835 |
TP53,KRAS,CTNNB1,HRAS,IDH2,IDH1,AKT1,PIK3CA,TERT,EWSR1,PTEN |
| 4.191e-03 | -5.47 | meningothelial | COSMIC cancer mutations | meningothelial | 18 | 11 | 16828 | 4835 |
RB1,HRAS,KRAS,CDKN2C,NF2,AKT1,TERT,PIK3CA,SMAD4,SUFU,PTEN |
| 4.191e-03 | -5.47 | ependymoma_Grade_II | COSMIC cancer mutations | ependymoma_Grade_II | 18 | 11 | 16828 | 4835 |
RB1,HRAS,KIT,CTNNB1,KRAS,IDH2,NF2,IDH1,AKT1,TERT,PTEN |
| 4.191e-03 | -5.47 | supratentorial | COSMIC cancer mutations | supratentorial | 18 | 11 | 16828 | 4835 |
IDH2,TP53,CTNNB1,SMARCB1,PTEN,TERT,FGFR1,IDH1,HRAS,KRAS,SUFU |
| 4.191e-03 | -5.47 | meninges-meningioma-meningothelial | COSMIC cancer mutations | meninges-meningioma-meningothelial | 18 | 11 | 16828 | 4835 |
PTEN,SUFU,SMAD4,PIK3CA,TERT,CDKN2C,AKT1,NF2,KRAS,RB1,HRAS |
| 4.191e-03 | -5.47 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-marginal_zone_lymphoma | 18 | 11 | 16828 | 4835 |
CREBBP,IDH1,TNFAIP3,MAP2K1,IDH2,NOTCH2,CDKN2C,MYD88,EZH2,CD79B,EP300 |
| 4.191e-03 | -5.47 | salivary_gland-carcinoma-acinic_cell_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-acinic_cell_carcinoma | 18 | 11 | 16828 | 4835 |
FBXW7,ETV6,TP53,CTNNB1,MET,PTEN,PIK3CA,KRAS,HRAS,SMAD4,STK11 |
| 4.196e-03 | -5.47 | oxoacid metabolic process | biological process | GO:0043436 | 810 | 273 | 18204 | 5365 |
ACOT8,ACAT1,BPGM,MECR,AMT,ALDH1A3,CYP1B1,NDP,AZIN2,TLR2,TPST1,PDHA1,MTHFS,GSTM4,MGAT4A,ELOVL1,ALOX5AP,ANKH,LIPT2,PLP1,ECHDC1,GGT7,RDH10,ARG2,HPGDS,CYP2C9,ELOVL6,CBR4,MPST,SLC25A44,FOLR1,ADIPOR1,PYCARD,ABHD5,AKR1B1,BCKDK,SDS,MSMO1,DDAH1,CYP4F12,CYP3A5,PPAT,SYK,FA2H,EGLN3,SLC23A2,PRKAB1,GLUL,GPAM,ADIPOQ,SLC2A1,SHMT1,MCAT,PCBD1,NUDT7,CRYM,PAPSS2,DDAH2,PPARG,ASNSD1,ACOX1,LIPA,SLC16A1,CYP7A1,ELOVL4,PGK1,GSTO1,FAH,SLC25A12,ADH1A,SESN2,SLC25A32,GSTA1,CDO1,GSTO2,GNPDA1,LYPLA1,HEXB,MGST3,AASDHPPT,PPM1K,CYP2C18,PYCR1,SLC38A1,MECP2,HACD1,ETFB,CYP4V2,GAPDH,AKR1C1,PTGDS,HNMT,GNPDA2,AKR1C2,ABHD2,HSD17B8,IDH2,LEP,UGT2A3,ATF4,SORD,UGDH,ENO2,FAHD1,ADH1B,ACO2,AIG1,GGTA1,ACSS2,SCD5,NDUFAB1,COMT,SLC25A21,UGT1A1,CRABP2,PTGES3,MTHFD2L,FGFR1,DBT,CYP39A1,GNPAT,CSGALNACT1,DLST,DECR2,PEDS1,LYPLA2,PGM1,CYGB,ACBD7,ST6GAL1,TP53,HADHA,GMPS,SERINC3,IDO1,FADS2,ACCS,ELOVL3,CYP2C8,CYP1A1,P4HA2,ATP1A2,PLAA,TST,GAMT,MTARC2,TECR,RGN,GPX4,AZIN1,XBP1,EHHADH,IDH1,ACACA,SCPEP1,EGLN2,AKR1A1,GAD2,PLA2G5,ILVBL,KGD4,LDHAL6B,RIMKLA,FKRP,PFKFB2,SULT1A3,ADTRP,PCCB,PDHB,ACO1,HACD4,PLA2G15,PEX13,PGAM1,FMO1,AMACR,ABHD14B,SEPHS1,GSTM2,PYCR2,LDHA,SLC5A6,GCLC,GPX1,CPT1B,ACADS,GPT,CPT2,LIAS,GSTP1,CRTAP,SLC2A3,OSBP,ASPA,HSD17B10,CRYL1,UCP2,IGF1,DPEP1,HADH,ETFA,CYP4F22,MDH1,SLC6A8,RIMKLB,EPHX1,OGDHL,ABHD12,MTAP,HACD3,BRCA1,MGST2,CYP2D6,PCK2,ACOT6,IREB2,PRKAG1,SLC25A17,IDH3B,ST3GAL1,PNPLA8,CD36,CMAS,LDHB,ASRGL1,NUDT19,ODC1,PHYH,CRAT,ELOVL7,SLC25A42,ADSS2,PC,GFPT1,SLC1A3,CYP2F1,GLYAT,PPARA,UST,ACADSB,SULT1B1,GNMT,ERRFI1,VDAC1,MBLAC2,DLAT,OAT,ENO1,HTR2A,MORC2,MIF,CYP26A1,ADIPOR2,DEGS1,AUH,PTGES,SEPHS2,PLA2G4B,ABHD10,ACAA2,ALDH1L1,ABHD6,IER3,HEXA,NANP,HACD2,SUCLG2,IDH3A,MMUT,ACSL4,CYP27A1,CYP4F8,TPH2 |
| 4.197e-03 | -5.47 | selenium binding | molecular function | GO:0008430 | 9 | 7 | 18094 | 5411 |
SELENOF,GPX3,SELENOP,GPX4,SELENOT,DIO1,DIO2 |
| 4.197e-03 | -5.47 | protein-disulfide reductase (NAD(P)H) activity | molecular function | GO:0047134 | 9 | 7 | 18094 | 5411 |
TXNRD2,SELENOT,TXNDC17,TXNRD1,TXNRD3,PGK1,TXN |
| 4.197e-03 | -5.47 | snRNP binding | molecular function | GO:0070990 | 9 | 7 | 18094 | 5411 |
RBM23,PRPF31,LEMD3,SNRPA,SNRPB,SNRPN,SNRPD3 |
| 4.198e-03 | -5.47 | KCNJ4 (potassium inwardly rectifying channel subfamily J member 4) | protein interactions | 3761 | 16 | 10 | 19454 | 5460 |
GPR35,SNTA1,CASK,KCNJ2,DLG4,DLG1,LIN7B,LIN7C,CAV3,GNGT2 |
| 4.198e-03 | -5.47 | ZSWIM9 (zinc finger SWIM-type containing 9) | protein interactions | 374920 | 16 | 10 | 19454 | 5460 |
WTAP,PTGES3,RIGI,JUNB,PRNP,CBX3,FHL3,ZMYM4,NOL4,ZMYM2 |
| 4.198e-03 | -5.47 | MKKS (MKKS centrosomal shuttling protein) | protein interactions | 8195 | 16 | 10 | 19454 | 5460 |
HSPA8,STUB1,ICA1,CDR2,HSP90AA1,STK16,ZBED1,HSCB,PTN,EEF1G |
| 4.198e-03 | -5.47 | EFCAB7 (EF-hand calcium binding domain 7) | protein interactions | 84455 | 16 | 10 | 19454 | 5460 |
DVL2,CSK,H1-5,MYL12B,YWHAG,AKAP14,RNF34,SOX2,TTC23,NRGN |
| 4.198e-03 | -5.47 | BOK (BCL2 family apoptosis regulator BOK) | protein interactions | 666 | 16 | 10 | 19454 | 5460 |
NOA1,RIGI,BCL2A1,BNIP3L,ESR2,MYC,BAD,BAK1,MCL1,TESPA1 |
| 4.198e-03 | -5.47 | HIVEP3 (HIVEP zinc finger 3) | protein interactions | 59269 | 16 | 10 | 19454 | 5460 |
TNFRSF1B,TOP3B,GRSF1,TRAF2,AGR2,WWP1,HNRNPL,NUP35,TRAF1,VIRMA |
| 4.198e-03 | -5.47 | DPYD (dihydropyrimidine dehydrogenase) | protein interactions | 1806 | 16 | 10 | 19454 | 5460 |
LXN,FBXO22,VIRMA,RIGI,QNG1,STX18,CLK1,CHAC2,RPE,GAPDH |
| 4.198e-03 | -5.47 | Arhgap6 (Rho GTPase activating protein 6) | protein interactions | 11856 | 16 | 10 | 19454 | 5460 |
SSBP1,TIMM13,PCNA,RPS29,KPNA2,TRMT112,POLDIP2,SERPINH1,SLC25A12,PRDX4 |
| 4.198e-03 | -5.47 | PDPN (podoplanin) | protein interactions | 10630 | 16 | 10 | 19454 | 5460 |
IL17F,RBCK1,TMEM177,TMEM14B,TOM1L1,SLC38A7,MPDU1,GALNT12,DDX39A,MBLAC2 |
| 4.198e-03 | -5.47 | ESPN (espin) | protein interactions | 83715 | 16 | 10 | 19454 | 5460 |
FAAP100,PRMT2,EEF1AKMT3,RAB37,UBXN6,CTSC,RIGI,SNRNP40,HNRNPL,FAM98A |
| 4.198e-03 | -5.47 | ZFAND1 (zinc finger AN1-type containing 1) | protein interactions | 79752 | 16 | 10 | 19454 | 5460 |
PSMA3,PSMC5,PSMD1,CUL3,PSMC4,TRMT5,RBM22,GPR35,SMAD4,PSMA1 |
| 4.198e-03 | -5.47 | SYT9 (synaptotagmin 9) | protein interactions | 143425 | 16 | 10 | 19454 | 5460 |
SYNCRIP,TMBIM6,DNAJC5,SNAP25,TUBB,HSPA5,CSNK1A1,TMEM50A,UTP25,LRP6 |
| 4.209e-03 | -5.47 | RAVER1 (ribonucleoprotein, PTB binding 1) | protein interactions | 125950 | 164 | 62 | 19454 | 5460 |
PPP2R1A,SUPT5H,TP53,TNRC6C,RHOBTB1,GRAP2,CAPZA2,COX8A,BAG2,RTCB,ABCE1,ZC3H7A,S100B,TRIP4,RUSF1,CNOT6L,TRIM37,CNOT7,HNRNPA1,XPO1,CNOT2,MOV10,DDX1,CHCHD1,AK2,TUBG1,FUBP3,NUP35,CDC5L,EGLN3,HNRNPL,RPL35A,CDKN1A,HAUS2,PAX9,FEM1A,RPA2,RNF113A,P4HA2,RPA3,STAU1,B9D2,CERS2,AR,GORASP2,TIA1,ANAPC15,MYC,CDC16,HTRA2,MCAT,UHMK1,CYP1A1,DCAF4,GADD45B,PHKB,LMBR1L,CCNF,ESR2,CDC20,SNRNP40,EIF4H |
| 4.210e-03 | -5.47 | learning or memory | biological process | GO:0007611 | 276 | 102 | 18204 | 5365 |
SNAP25,PAK5,DLG4,ARF4,NEUROD2,NETO1,PRNP,CCL11,C1QL1,VDAC1,LDLR,HTR2A,LARGE1,ACSS2,SRC,COMT,ATXN1L,BGLAP,CREB1,UBE3A,NTF4,PAFAH1B1,BRINP1,CHST10,ARL6IP5,EGR2,PSEN1,PTN,KCNK10,NTRK2,SYT4,OPRK1,TACR1,GPRASP3,PLCB1,BTG2,CHRNA7,CHRNB2,PRRT1,MEF2C,NCSTN,PTPRZ1,B2M,UCN,MECP2,SLC6A4,ADCY3,S100B,PAX6,TPBG,CLN8,PDE1B,DRD3,AGER,NOG,CDK5,DKK1,SLC6A1,MME,YTHDF1,ELAVL4,OXTR,PPP1R1B,DBH,ASIC1,CX3CR1,EIF4A3,SLC1A1,CRHBP,GRPR,PPT1,PAK6,SLC7A11,KRAS,EP300,CAMK2N1,CNR1,ATP1A2,PICALM,PIAS1,PAIP2,KIT,TACO1,TLR2,TNR,FEN1,GRIA1,ADNP,FGF13,TUBA1A,OPRL1,RAG1,DRD1,TMOD2,JPH4,VLDLR,ATAD1,FOS,PTEN,SLC11A2,EIF4EBP2,ATP8A1 |
| 4.214e-03 | -5.47 | ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3) | protein interactions | 489 | 226 | 82 | 19454 | 5460 |
S1PR4,TLR8,RMDN3,GPR173,GPR89A,MGST3,FBXO22,ACVR1C,ABHD12,CLRN2,TMED5,ENTPD4,GPR17,TMED4,GLT8D2,HFE,CISD1,CGRRF1,CYP4F22,VMP1,CD40,HCFC2,TSPAN15,TLCD1,CERS6,TIMMDC1,KDELR2,SEC62,SLC35E1,HACD2,EIF3J,CFTR,SDC2,GHITM,GPR35,ARMCX3,ELOVL1,LEMD3,PTK7,GLT8D1,CD274,ACSL4,MPDU1,SPINT2,EXT1,MARCHF4,ARL6IP5,EXTL2,UQCRH,FAM174A,FAR2,LRRTM1,CCR6,FAM20B,TMEM70,LRRC8B,PEX3,AREL1,TMEM87A,HNRNPA2B1,TMED1,HAPSTR1,TSPAN17,LPAR2,MAN1A2,SCD5,TNFSF8,SRPRB,HS2ST1,TOP3B,FAM162A,CYB5R1,TLR3,SURF4,CA14,HDAC11,KDELR1,AQP3,SLC4A8,DHRS7B,KCNF1,GNAI3 |
| 4.215e-03 | -5.47 | Ubiquitin Conjugating Enzyme | gene3d domains | 3.10.110.10 | 54 | 25 | 14470 | 4137 |
UBE2S,RWDD3,UBE2E3,UBE2W,RWDD1,KRAS,UBE2V2,UBE2D3,UBE2E2,UBE2A,IMPACT,UBE2B,UBE2V1,UBE2F,TSG101,UBE2G2,UBE2K,UBE2L3,UBE2M,UBE2H,UBE2I,UBE2D1,RWDD4,RNF14,UBE2N |
| 4.215e-03 | -5.47 | response to antibiotic | biological process | GO:0046677 | 37 | 19 | 18204 | 5365 |
MEF2C,RSRC1,SLC1A3,EZH2,RPL23,HYAL2,HSP90AA1,VPS54,ALPL,KDM1A,JAK1,TP53,CYB5R4,CRIP1,PPP2CB,CDKN1B,GRIA1,MDM2,JAK2 |
| 4.215e-03 | -5.47 | amine biosynthetic process | biological process | GO:0009309 | 37 | 19 | 18204 | 5365 |
GPR37,SLC6A3,ASMT,SAT2,MOXD1,AZIN1,NR4A2,SRM,TGFB2,AZIN2,AANAT,DBH,OAZ3,OAZ2,PAOX,ODC1,SAT1,OAZ1,HAND2 |
| 4.215e-03 | -5.47 | cell surface toll-like receptor signaling pathway | biological process | GO:0140895 | 37 | 19 | 18204 | 5365 |
TRAF6,MYD88,CD14,TLR2,NMI,TIRAP,IRAK4,TICAM2,NFKBIA,TICAM1,TBK1,LY96,OAS1,TMEM126A,TLR4,PIK3AP1,TLR5,IRF3,PRKCE |
| 4.215e-03 | -5.47 | negative regulation of organ growth | biological process | GO:0046621 | 37 | 19 | 18204 | 5365 |
STK3,CAV3,PPARA,NOG,MIR1-1,GSK3A,VGLL4,FXN,TOMM70,PI16,RGS2,MIR25,G6PD,STK4,SAV1,MIR873,SLC6A4,PTEN,FOXP1 |
| 4.234e-03 | -5.46 | Spliceosome, U1-snRNP | KEGG pathways | M00351 | 10 | 8 | 7161 | 2463 |
SNRNP70,SNRPE,SNRPD2,SNRPD1,SNRPD3,SNRPA,SNRPG,SNRPB |
| 4.234e-03 | -5.46 | Spliceosome, U1-snRNP | KEGG pathways | hsa_M00351 | 10 | 8 | 7161 | 2463 |
SNRPD3,SNRPG,SNRPA,SNRPB,SNRNP70,SNRPE,SNRPD1,SNRPD2 |
| 4.235e-03 | -5.46 | ADGRG5 (adhesion G protein-coupled receptor G5) | protein interactions | 221188 | 92 | 38 | 19454 | 5460 |
EDEM2,TMED7,TMUB1,CERS6,ACVR1B,GPM6A,GPM6B,MIA2,BMPR1A,FSTL1,LRP10,CRELD1,FAM3C,TSPAN3,SIGMAR1,TMX4,TMEM59,SLC29A1,IFNGR1,DCAKD,SYNGR2,GJC1,SLC19A2,SRPK2,ACP2,SPPL3,GJA1,SERINC1,FZD6,FZD3,PTPN1,NUS1,FITM2,OSBPL8,TMEM179B,REEP6,SLC6A6,TSPAN10 |
| 4.235e-03 | -5.46 | GP9 (glycoprotein IX platelet) | protein interactions | 2815 | 92 | 38 | 19454 | 5460 |
TMEM106B,GPAA1,RUSF1,RDH10,SCD5,MIA2,APPBP2,BSCL2,PGAP4,FKBP8,RIGI,RAD21,FAM234A,EDEM3,SMAD1,GLRB,DIPK1A,ALG11,TUBA1A,LEMD3,DHRS7B,PIGK,SRPRA,SFXN2,FZD6,DIPK2A,ADGRG1,ASIC1,LRRC8A,ABHD12,TM9SF4,NUDT1,ENTPD4,SYNJ2BP,ITPRIPL2,TMEM106C,GGCX,TMEM30A |
| 4.255e-03 | -5.46 | regulation of transforming growth factor beta production | biological process | GO:0071634 | 32 | 17 | 18204 | 5365 |
SMAD3,FOXP3,CX3CL1,BMPR1A,TGFB2,LILRB1,ATP6AP2,XCL1,FURIN,CD2AP,LUM,TYROBP,CD200,SMAD4,IL13,MIR149,CD46 |
| 4.257e-03 | -5.46 | MAP2K2 (mitogen-activated protein kinase kinase 2) | protein interactions | 5605 | 267 | 95 | 19454 | 5460 |
HSP90B1,CDK1,RPA2,CDC42,TPT1,WDR83,HSPA5,HMGB1,ARMCX5,PGK1,RHOU,DVL2,RPA3,NCAPG2,SUB1,CSK,DUSP3,EIF4H,TXN,TRAF7,TUBA1B,NFE2L2,MAP2K3,RIGI,MDC1,MEPCE,HNRNPK,WASL,CSE1L,PSMA5,HINT1,LRRN4CL,SLC25A11,MAP1B,NME2,GLO1,COPS5,FAM20C,ISYNA1,CALR,CDK9,DCK,EEF1AKMT3,SLC25A3,MAP2K1,RPE,RND2,PGRMC1,ACTL6A,HSCB,HSPA8,PEBP1,BMPR1A,DNAJB6,OSGEP,HSP90AA1,YWHAZ,CKB,BAG3,IREB2,TUBB,LAMTOR3,FAM91A1,RHOBTB1,OTULIN,GDI2,TUBB4B,EZH2,EEF2,TUBA1A,RAF1,ETFA,TNF,BAG2,PDIA6,RTCB,PCNA,YWHAB,TST,ZNF207,YWHAG,XPO1,YWHAH,P2RY10,BABAM1,GSTM3,UBXN6,PRDX1,MACROD1,HSP90AB1,RHOH,HNRNPL,EIF2S1,MAGED2,WDR6 |
| 4.258e-03 | -5.46 | Signaling by VEGF | REACTOME pathways | R-HSA-194138 | 338 | 129 | 10285 | 3229 |
ELMO2,FGF17,PSMD7,NCK1,WASF3,ANGPT1,PSME1,ELMO1,PPP5C,SPTBN1,PPP2R1A,UBB,PRKCA,PRKACB,PSMD14,PSMC4,VAV2,PSMB5,PSMA3,PSMB1,AHCYL1,CTNND1,PIK3R1,PSMB7,JAK2,PSMD3,BRAP,CSK,DLG4,PSMB6,PSMA2,PSMB10,IL2,PSMC5,FGFR1,PSMB11,PSMA4,VEGFC,SPRED2,IL2RA,PSMB9,HBEGF,PSMD6,PSME2,FGF3,JUP,NEFL,DUSP10,MAP3K11,PSMD12,FGF7,JAK1,MAPKAPK3,CSF2,PRKCB,RAP1A,SHC3,AKT2,ROCK1,FGF10,DUSP9,SRC,ROCK2,PSMD10,FRS3,RAF1,WDR83,UBA52,FGF22,KRAS,MAP2K1,RAP1B,PPP2R5A,FGF1,DUSP6,CDC42,YWHAB,PIK3R2,IL2RG,PSMB3,PEBP1,PPP2R5E,SPTAN1,PSMA5,FGF23,PAQR3,MET,VEGFA,DUSP1,SEM1,PSMB4,CTNNA1,PAK2,RASGRP3,SHC1,SPRED1,PHB1,PSMD4,IL3,ITGAV,RPS27A,CAV1,PSMA1,CTNNB1,PSMC3,PSMC1,CUL3,VWF,CAMK2G,LAMTOR3,IL2RB,FGF16,PEA15,AKT1,AKT3,PSMA6,HSP90AA1,PIK3CA,HSPB1,NRP1,NCKAP1,PSMD1,PSMB2,CYFIP2,IL5,HRAS,LAMTOR2,PPP2CB,KIT |
| 4.262e-03 | -5.46 | Photodynamic therapy-induced AP-1 survival signaling. | WikiPathways | WP3611 | 51 | 28 | 5310 | 1910 |
BAX,TRAF2,MAP2K6,MAP2K3,CCNA2,BCL2L1,IL6,NFE2L2,TP53,MCL1,FOS,RB1,CCND1,HBEGF,TRAF6,ELK1,JUNB,BAK1,FASLG,JUN,FGF7,IFNG,TNFSF10,CDKN1A,HSP90AA1,FAS,TNF,IL2 |
| 4.274e-03 | -5.46 | Prostacyclin signalling through prostacyclin receptor | REACTOME pathways | R-HSA-392851 | 19 | 12 | 10285 | 3229 |
GNG11,GNG5,GNB4,GNG10,GNG7,GNG13,GNB1,GNG3,GNB3,GNGT2,GNG12,GNG2 |
| 4.274e-03 | -5.46 | Translesion Synthesis by POLH | REACTOME pathways | R-HSA-110320 | 19 | 12 | 10285 | 3229 |
RPA2,UBB,RFC4,UBA52,RPS27A,PCNA,UFD1,RFC3,RFC5,RCHY1,RFC2,RPA3 |
| 4.283e-03 | -5.45 | Signalling to p38 via RIT and RIN | REACTOME pathways | R-HSA-187706 | 249 | 98 | 10285 | 3229 |
IL2RG,YWHAB,FGF1,PPP2R5A,DUSP6,PAQR3,MET,PSMA5,FGF23,PPP2R5E,SPTAN1,PEBP1,PSMB3,FRS3,PSMD10,DUSP9,SRC,FGF10,RAP1B,KRAS,MAP2K1,WDR83,FGF22,UBA52,RIT1,RAF1,FGF16,LAMTOR3,CAMK2G,IL2RB,VWF,CUL3,PSMC1,IL5,KIT,PPP2CB,LAMTOR2,HRAS,PSMD1,PSMB2,PEA15,PSMA6,RASGRP3,SHC1,PSMB4,SEM1,DUSP1,PSMC3,PSMA1,RPS27A,IL3,PHB1,PSMD4,SPRED1,JAK2,PSMB7,PSMD3,PSMB1,PSMB5,PSMA3,PSMC4,PSMA4,PSMB10,PSMB11,FGFR1,IL2,PSMC5,PSMA2,PSMB6,CSK,BRAP,DLG4,PPP5C,RIT2,SPTBN1,PSME1,ANGPT1,FGF17,PSMD7,PSMD14,PPP2R1A,UBB,CSF2,JAK1,FGF7,PSMD12,SHC3,RAP1A,PSME2,FGF3,HBEGF,PSMD6,IL2RA,SPRED2,PSMB9,MAP3K11,DUSP10,NEFL |
| 4.286e-03 | -5.45 | Histone-fold | interpro domains | IPR009072 | 72 | 32 | 18521 | 5414 |
CENPW,SUPT3H,H2AZ2,SUPT7L,H2BC11,H2AC1,H2AC6,H2AC25,NFYB,H2AC4,DRAP1,H2AB1,SOS2,H2AC7,H2BC14,TAF9,H2BC17,H2BC12,H2AC14,POLE3,H2AJ,H2BC9,H2BW1,H2AZ1,TAF11,CHRAC1,H2AX,POLE4,DR1,H2BC1,MACROH2A1,MACROH2A2 |
| 4.290e-03 | -5.45 | LENG8 (leukocyte receptor cluster member 8) | protein interactions | 114823 | 158 | 60 | 19454 | 5460 |
RGL1,APOBEC3C,CRYAB,SNRPA,RPA3,DDX39B,TMEM263,WDR55,TACR3,AATF,KDM1A,RPL4,MYOZ3,CEP70,AR,PPP1CC,BAG3,MYC,PRMT6,CIAO1,OAZ1,RIT1,MECP2,PLEKHJ1,SYT2,CSNK2B,PRMT5,CCNF,APEX1,ESR2,SNRNP40,RPL13A,MSX2,ZNF263,RAF1,SUPT5H,SMARCB1,SKA1,RPL31,RPL28,RIGI,TFG,SMN1,KRAS,SEM1,LASP1,ASF1A,MAPK1IP1L,FGF12,HNRNPA1,SUV39H1,MPHOSPH6,TSG101,PHB1,EGLN3,SURF6,NUP35,HNRNPL,CAND1,HYPK |
| 4.290e-03 | -5.45 | EPHA8 (EPH receptor A8) | protein interactions | 2046 | 158 | 60 | 19454 | 5460 |
CDK5RAP3,ESYT1,CBL,RAB3A,OSBPL8,PIK3R1,DDRGK1,CTNNB1,LMAN1,AIP,HACD3,WDR6,SRPRA,PTPN1,XPO5,SEC23A,STX5,NUDT19,STIM1,HGS,CRKL,TBK1,UBIAD1,NUDCD3,LAMB2,G3BP1,ARF4,TFG,NDUFA4,PIK3CG,MRPS18B,ARFGAP3,SCFD1,EPHA2,C9orf72,VEZT,SEC13,RAB11A,PYCR2,GORASP2,COPE,BMP1,EFNA5,PSMC5,VAPB,ARCN1,LEMD3,RABL3,NTPCR,YKT6,EMC1,HSCB,YTHDF1,PIK3R2,FTSJ1,HSPA5,APMAP,PEBP1,BANF1,MTDH |
| 4.295e-03 | -5.45 | TP63 (tumor protein p63) | protein interactions | 8626 | 302 | 106 | 19454 | 5460 |
NACC2,ATP5PO,EHHADH,SEC62,CDKN1A,NFIL3,PPP2R2C,UBE2D3,PSENEN,EVA1A,SNRPA,DPH6,EP300,FAS,BRCA1,PSMD14,ILK,DNAJB6,ARMC7,TM2D2,NFYA,HNRNPAB,PMPCA,SFN,CFAP20,TRMT11,ANAPC2,PLS3,POLR2C,H1-3,SOX2,ISG15,NCSTN,ASPM,TRIM26,PELI1,PIWIL1,CCT8,ATF3,IKBKB,DDX23,HNRNPD,PRDX1,PPP2R5A,EMC6,GAS8,HNRNPL,RNF144B,HSP90AB1,RPRD1B,WWP1,RPLP0,SUMO1,UQCRC1,AGO1,FBXW7,USP8,MIR6505,HSPA5,PML,FLCN,ZFAND6,IGF2BP1,STK11,CDC16,CSK,ATP5F1A,NONO,RPL13A,CDC20,FERMT2,STUB1,CSNK2B,COA5,SLC25A45,UBE2I,IK,PPP4C,ILF2,OR6M1,RPSA,TP53,EEF1A1,NDST1,EMX1,TGFBR2,HNRNPK,APH1A,ILDR1,RPL3,DHX9,SMAD4,CRBN,RPL24,UPK1A,TOPBP1,NFKB1,HP,CSNK2A1,PET117,SEMA3C,MDM2,RPL12,SYNCRIP,RCHY1,GATAD1 |
| 4.300e-03 | -5.45 | SHC1 (SHC adaptor protein 1) | protein interactions | 6464 | 350 | 121 | 19454 | 5460 |
SMAD4,SHC1,CD247,USP15,MOV10,GRAP,FCGR2A,CD81,FCGR2B,DAG1,PRNP,LCP2,FAM118B,CDC5L,AIFM1,SSBP1,RB1,GEMIN7,GRAP2,AKAP12,DDR1,TMED1,SLC25A11,SOS2,IGF1R,NTRK2,EPHA2,AP2A1,IL2,CSK,IL2RB,PTPN11,PYCR2,MTPN,AR,HMOX2,STAT5A,YES1,SRC,GAB1,CTTN,TUBA1B,PRKRA,UBASH3B,JUP,FGFR1,PRKCA,SCLT1,MET,ACACA,SPTBN1,PPP1R8,CFTR,KDM1A,PIK3R2,FBXW7,GRPEL1,HSPA5,INPPL1,MME,CBL,HAX1,HSPB1,PIK3R1,PRDX1,PPP2R5A,WWP2,YWHAG,XPO1,SPTAN1,TRIM15,HSP90AB1,DNM2,S100A8,MAP1LC3A,CORO1C,TUBB4B,PLS3,VPS33A,GHR,AP2S1,CRKL,ERRFI1,TOP3B,ACTN4,TUBA1A,EEF2,EPHA4,KRAS,KIT,RUVBL1,ANP32B,PLSCR1,HNRNPA2B1,RUVBL2,CCT2,SP1,OSGEP,HSP90AA1,NTRK3,ILK,HNRNPC,SFN,EPS8,ACTB,TUBB,CLIC4,JAK2,S100A6,AP2M1,PRMT5,CD3G,PIH1D1,IL2RG,SYK,GH1,IL6ST,STXBP1,ITGAV,HSPA8,DDX5 |
| 4.302e-03 | -5.45 | GLO1 (glyoxalase I) | protein interactions | 2739 | 95 | 39 | 19454 | 5460 |
HNRNPA1,DDRGK1,GLO1,GMPS,PGAM1,NRP1,UBE2H,HSPB1,GLOD4,AGR2,PREP,IGBP1,AKR1B1,MRPL13,FABP5,OPTN,CCNF,SLC25A12,PNP,UMPS,NEK7,CFTR,SHOC2,TFCP2,RPA2,PSMG4,EWSR1,SOS2,PRDX6,BAP1,RPA3,SOD1,PML,FOS,IMPA2,CPLX1,SAR1B,UFL1,HSPE1 |
| 4.309e-03 | -5.45 | Kcnk1 (potassium channel, subfamily K, member 1) | protein interactions | 16525 | 44 | 21 | 19454 | 5460 |
SEC61A1,SLC39A7,SEC61B,CXCR4,ATP5PD,CAV1,ATP5F1B,CERS2,SNRPA1,DERL2,ATP5F1D,SLC35E1,ATP5F1A,ATP5PB,SLC35F6,SEC22B,TRAPPC13,TFRC,ATP5PO,SURF4,GOLGA5 |
| 4.309e-03 | -5.45 | CCS (copper chaperone for superoxide dismutase) | protein interactions | 9973 | 44 | 21 | 19454 | 5460 |
YWHAG,SOX2,CCS,GMPS,MYC,DPH5,PCK2,GMPPB,PPIL3,PMPCA,RIT1,FAS,GSTO1,NIF3L1,CAPZA2,DNAL4,SOD1,SUCLG2,TXN,SLC31A1,ACTB |
| 4.309e-03 | -5.45 | OPA3 (outer mitochondrial membrane lipid metabolism regulator OPA3) | protein interactions | 80207 | 44 | 21 | 19454 | 5460 |
KDM1A,STARD7,SLC15A1,IDE,IMMP2L,ACP2,ESR2,PARL,AIFM1,ATP5PF,CLPB,OPA3,ATP5PO,TIMM23,STOML2,PRMT6,COX5A,MTCH2,ATP5F1A,SUV39H1,DDRGK1 |
| 4.309e-03 | -5.45 | USP44 (ubiquitin specific peptidase 44) | protein interactions | 84101 | 44 | 21 | 19454 | 5460 |
PSMC4,SOX2,EZH2,DLX1,NGB,H2BC1,POLR2G,PTTG1,MRPL53,TCOF1,KRR1,FOXP3,PSMC5,CETN3,HDAC3,MRPL23,MRPS21,SATB1,MRPL40,PSMC1,CETN2 |
| 4.309e-03 | -5.45 | ETHE1 (ETHE1 persulfide dioxygenase) | protein interactions | 23474 | 44 | 21 | 19454 | 5460 |
GORASP2,GMPS,GLRX5,CFL2,TP53,PMPCA,EHHADH,ACO2,ATG9A,FXN,GSTP1,GSTO1,SPOP,GATD3,CYB5A,IDH1,CLIC4,IGSF21,LRIF1,SUCLG2,PRNP |
| 4.309e-03 | -5.45 | TMEM139 (transmembrane protein 139) | protein interactions | 135932 | 44 | 21 | 19454 | 5460 |
TRIM68,SMCO4,SFTPC,SLC35A1,CTSA,CYB5B,FAXDC2,SEC22B,PLPP4,TMEM19,MARCHF5,VAMP5,PMP22,AGTRAP,UBIAD1,TMEM107,TMEM60,NSG1,CD151,TRAF3IP3,YIF1A |
| 4.310e-03 | -5.45 | Anapc2 (anaphase promoting complex subunit 2) | protein interactions | 99152 | 36 | 18 | 19454 | 5460 |
MAD2L1,CDC20,FZR1,GNPTG,ATP5F1E,ANAPC16,ANAPC2,TMEM263,ANAPC4,CDC23,GGCX,NOS1AP,ANAPC13,NEK2,ANAPC15,CDC16,PYCR2,CDC26 |
| 4.310e-03 | -5.45 | SNRNP48 (small nuclear ribonucleoprotein U11/U12 subunit 48) | protein interactions | 154007 | 36 | 18 | 19454 | 5460 |
SF3B6,SRSF8,GPX4,ZMAT5,SF3B1,SNRPD2,SNRPD3,ELOVL6,SNRPG,ESR2,ENKD1,CDCA7L,SNRPN,SUPT5H,SNRPB,ZCRB1,SNRPE,TFIP11 |
| 4.310e-03 | -5.45 | NR2E1 (nuclear receptor subfamily 2 group E member 1) | protein interactions | 7101 | 36 | 18 | 19454 | 5460 |
UPF3B,ARL10,DDX5,MTDH,HDAC5,ZMYM2,KDM1A,DGCR8,HDAC3,RERE,GNB4,SMURF1,SUFU,TNRC6C,MECR,TMSB10,DROSHA,SP1 |
| 4.310e-03 | -5.45 | SMTN (smoothelin) | protein interactions | 6525 | 36 | 18 | 19454 | 5460 |
NLE1,PML,EWSR1,PTEN,SPPL3,TRIM37,TRIM52,APEX1,RIGI,ESR2,MYC,MOV10,CDK4,TP53,BTF3,BRMS1,LMNA,BRCA1 |
| 4.310e-03 | -5.45 | BROX (BRO1 domain and CAAX motif containing) | protein interactions | 148362 | 36 | 18 | 19454 | 5460 |
SORD,NQO1,MDH1,RHOB,CHMP1A,RPA2,NUDT19,PGM1,COPS5,SPR,ACO2,NFYA,CGAS,LDHA,TCEA1,GATD3,CMBL,RPA3 |
| 4.310e-03 | -5.45 | RAPGEF1 (Rap guanine nucleotide exchange factor 1) | protein interactions | 2889 | 36 | 18 | 19454 | 5460 |
HRAS,RAP1B,RRAS2,RPS15,RIGI,VIRMA,SPATS2L,RAP1A,MOV10,TOP3B,LGR4,RAP2B,SHC1,FBXW11,RHOG,SLC20A1,CRKL,CBL |
| 4.310e-03 | -5.45 | ZNRF1 (zinc and ring finger 1) | protein interactions | 84937 | 36 | 18 | 19454 | 5460 |
UBE2D3,ATP1A2,ESR2,CAV1,UBB,UBE2V2,UBE2N,GLUL,UBE2E3,HBB,UBE2D1,ZNRF1,TSEN54,ATP1A1,UBE2W,UBE2E2,TOP3B,UBE2V1 |
| 4.310e-03 | -5.45 | UQCRFS1P1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 1) | protein interactions | 100128525 | 36 | 18 | 19454 | 5460 |
ESR2,SLC25A4,OXCT1,LAMTOR3,ZC3H11A,ACAT1,CCNF,IDH3A,ZMPSTE24,AGR2,NHERF1,MAP2K1,PPM1B,DDRGK1,MYC,TBK1,RAF1,MRPS35 |
| 4.312e-03 | -5.45 | AICDA (activation induced cytidine deaminase) | protein interactions | 57379 | 69 | 30 | 19454 | 5460 |
PGAM1,USP14,YWHAH,XPO1,USP15,EXOSC1,KPNA1,HSP90AA1,HSP90AB1,CCT7,UBE2L3,SUPT5H,FEN1,EXOSC8,EEF1A1,PPP2R1A,EXOSC3,TUBB4B,RNF126,EP300,RTCB,EXOSC4,PCNA,P4HA2,KPNA2,CTNNBL1,HNRNPA0,EIF2D,MSH6,HSPA5 |
| 4.312e-03 | -5.45 | MBTPS2 (membrane bound transcription factor peptidase, site 2) | protein interactions | 51360 | 69 | 30 | 19454 | 5460 |
CMAS,ATP6V1G1,EMC1,KDM1A,KRAS,SYVN1,BSCL2,EMC2,TTI2,FAM8A1,CYB5B,ANAPC13,PPP2R1A,MAX,TOMM22,MED9,CENPM,MRPL11,VIRMA,ERH,PSMD4,RPL35,RPLP2,LDLR,CAMLG,RIT1,MPHOSPH6,MRPL18,RBBP8,SLC35A1 |
| 4.312e-03 | -5.45 | ELOF1 (elongation factor 1) | protein interactions | 84337 | 69 | 30 | 19454 | 5460 |
INTS12,PHF12,POLR2L,FUBP3,POLR2B,SMURF1,OR52W1,FZR1,SUV39H1,CDC73,RIT1,LMNB1,BICD2,GPX4,SNAP23,TCEA1,IGF1R,PAX6,RNF41,KRAS,KDM1A,JUN,SUPT4H1,SNAP29,SUPT5H,POLR2G,POLR2C,POLR2D,ACACA,LMNA |
| 4.312e-03 | -5.45 | MTMR2 (myotubularin related protein 2) | protein interactions | 8898 | 69 | 30 | 19454 | 5460 |
DR1,DLG1,PML,EHD4,LIN7C,XPNPEP1,EYA3,LUC7L3,CASK,NUDT16,MTMR2,NEFL,SCHIP1,SMU1,TUBA1B,MRTO4,G6PD,RPL10,MTM1,RFC5,RPS17,RPL7A,MTMR12,MTRF1,CSK,RSPH1,NFKB1,CCDC22,BICD2,SNTA1 |
| 4.312e-03 | -5.45 | TIGD5 (tigger transposable element derived 5) | protein interactions | 84948 | 69 | 30 | 19454 | 5460 |
ZMYND19,ARMC8,BRD3,HRAS,LURAP1,TRMT10B,SPINT2,RAMP3,VIRMA,PRMT2,IKZF5,P3H1,MAGEA4,PNMA2,ADAMTS1,GNAQ,GID4,CORO6,LTBR,GID8,MAEA,EFNB1,P4HA2,MKLN1,THBS3,TRIM63,TRIM52,RANBP10,HSPA5,FTL |
| 4.315e-03 | -5.45 | regulation of calcium ion transport | biological process | GO:0051924 | 249 | 93 | 18204 | 5365 |
TMBIM6,GSTM2,CXCL12,PPP3CA,DRD3,MIR208B,CXCR4,XCL1,CAMK2G,PACSIN3,CACNB3,CX3CL1,STC1,LACRT,CXCL11,BAK1,VMP1,CTNNB1,GNAI2,G6PD,PLN,ATP1A2,SLC8A1,ATP1B1,F2,JPH4,SPHK2,PML,FKBP1A,CCL2,PPP3R2,MIR200C,CXCL10,NPSR1,SRI,CRHR1,MIR424,PLP1,SUMO1,CCR1,CACNB4,PRKCE,DRD1,MCHR1,VDAC1,TRPC1,LILRB1,STAC3,INPP5K,TMEM38B,CCL3,PLPP4,APLNR,TRIM27,PDE4B,PIK3CG,THY1,PSEN2,HOMER1,PRNP,HCRT,RCVRN,CCL5,CASK,CACNB2,CXCL9,IL13,MIR34A,SESTD1,MIR1-1,BAX,HPCA,GSTO1,HOMER3,TLR9,MRLN,NOS1AP,TSPO,MIR208A,CD4,MIR21,SELENON,STIM1,LILRA2,EPO,CLIC2,CAV1,LGALS3,UBASH3B,CAV3,GPR35,UCN,FKBP1B |
| 4.315e-03 | -5.45 | negative regulation of blood pressure | biological process | GO:0045776 | 50 | 24 | 18204 | 5365 |
BMPR2,UCN,IER3,ADRB1,SCPEP1,PPARA,SOD2,OPRL1,ADRB2,VEGFC,DRD3,GPR37L1,CNR1,ADRB3,SNX5,ADM2,ADIPOQ,TNF,PRCP,MIR17,ADORA1,ADRA1A,MKKS,APLN |
| 4.315e-03 | -5.45 | neuroinflammatory response | biological process | GO:0150076 | 50 | 24 | 18204 | 5365 |
JAK2,TYROBP,TNF,TLR3,CX3CL1,MIR181C,IFNG,CX3CR1,KCNJ8,IL13,TLR9,CLU,LARGE1,TLR2,IL1B,IL4,POMT2,VPS54,TLR6,AIF1,IFNGR1,AGER,BPGM,PSEN1 |
| 4.329e-03 | -5.44 | UBR1 (ubiquitin protein ligase E3 component n-recognin 1) | protein interactions | 197131 | 155 | 59 | 19454 | 5460 |
ZNF593,ARL4D,ATP6V1A,COX7A1,LY6G5C,BCL2L1,USP15,MRPL18,UBE2D1,XPO1,HNRNPA1,CRHBP,CFC1,EDEM1,UBE2A,POLDIP3,SEM1,CSE1L,CBX7,LDLRAD4,FAF1,ATF3,GADD45A,TP53I3,UBE2B,FAF2,SERPINB9,DNPH1,USP5,PARL,VIRMA,LAMTOR3,NRP1,SPCS3,KIAA1191,PKNOX1,BRCA1,NTAQ1,CHRDL1,MTG2,MYC,CUL2,MRM2,UCHL3,RASD1,GREM2,NSFL1C,NPB,ITM2B,FOS,ARL15,PRSS23,RPA2,METTL14,FEM1A,TIRAP,CDC42,FTH1,NUDT3 |
| 4.338e-03 | -5.44 | organellar large ribosomal subunit | cellular component | GO:0000315 | 56 | 26 | 19108 | 5553 |
MRPL41,MRPL20,MRPL11,MRPL13,MRPL52,MRPL33,MRPL16,MPV17L2,MRPL10,MRPL47,MRPL51,MRPL24,MRPL17,MRPL57,MRPL36,MRPL50,MRPL23,MRPL12,MRPL9,MRPL40,MRPL18,MRPL49,MRPL34,MRPL22,MRPS18A,MRPL53 |
| 4.338e-03 | -5.44 | mitochondrial large ribosomal subunit | cellular component | GO:0005762 | 56 | 26 | 19108 | 5553 |
MRPL9,MRPL40,MRPL18,MRPL49,MRPL34,MRPL22,MRPS18A,MRPL53,MRPL51,MRPL24,MRPL17,MRPL57,MRPL36,MRPL50,MRPL12,MRPL23,MRPL52,MRPL33,MRPL16,MPV17L2,MRPL10,MRPL47,MRPL41,MRPL20,MRPL13,MRPL11 |
| 4.350e-03 | -5.44 | response to type II interferon | biological process | GO:0034341 | 105 | 44 | 18204 | 5365 |
FASLG,ACTR2,DAPK3,TLR4,IFNGR1,TRIM21,STX8,CLDN1,AIF1,CD58,VAMP3,AQP4,CD40,JAK1,IRF1,SYNCRIP,TLR2,CCL3,VPS26B,CDC42EP2,RPL13A,CITED1,CDC42,DAPK1,PDE12,IRF8,CDC42EP4,MRC1,ZYX,IFNG,TP53,IL12B,RAF1,STAT1,BST2,TLR3,GAPDH,CYP27B1,CCL2,JAK2,CD47,CCL5,STXBP1,TNF |
| 4.350e-03 | -5.44 | gland morphogenesis | biological process | GO:0022612 | 105 | 44 | 18204 | 5365 |
FGF10,BAX,IL6,VDR,NFKB1,ID4,SFRP1,CDC42,NOTCH2,TWSG1,NHERF1,CRIP1,PAX6,TNF,POLB,CAV1,TGFB2,SOSTDC1,PML,NRP1,NKX3-1,PHB2,CCL11,LIPA,MSX2,NOG,STAT6,TGFBR2,PROX1,AR,CAPN1,MSN,SEMA3C,FGFR1,FGF7,CUL3,DDR1,DAG1,EPHA2,SRC,SOX9,FEM1B,PGR,TGFB3 |
| 4.351e-03 | -5.44 | UBC_2 | prosite domains | PS50127 | 39 | 19 | 12186 | 3388 |
UBE2M,UBE2H,UBE2G2,UBE2N,UBE2K,UBE2F,UBE2E2,UBE2V1,UBE2S,UBE2D1,UBE2W,UBE2B,UBE2L3,KRAS,UBE2I,UBE2V2,UBE2D3,UBE2E3,UBE2A |
| 4.355e-03 | -5.44 | positive regulation of smooth muscle cell apoptotic process | biological process | GO:0034393 | 20 | 12 | 18204 | 5365 |
STUB1,PPARG,MIR1-1,PDCD4,MIR28,IL12B,IFNG,MIR140,MIR24-1,SOD2,IL12A,ATF4 |
| 4.355e-03 | -5.44 | regulation of cell adhesion molecule production | biological process | GO:0060353 | 20 | 12 | 18204 | 5365 |
MIR101-1,MIR1298,MIR206,MIR222,MIR146A,IL1B,MIR144,MIR374A,MIR221,CXCL8,MIR20A,CAV1 |
| 4.355e-03 | -5.44 | regulation of nitric-oxide synthase biosynthetic process | biological process | GO:0051769 | 20 | 12 | 18204 | 5365 |
GSTP1,TLR4,SELENOS,JAK2,CCL2,MAP2K6,IFNG,TLR2,MIR132,MAP2K3,STAT1,AKAP12 |
| 4.355e-03 | -5.44 | regulation of metallopeptidase activity | biological process | GO:1905048 | 20 | 12 | 18204 | 5365 |
CLDN4,SVBP,MIR24-1,MIR17,MIR29C,DDRGK1,MIR205,MIR21,TIMP1,MIR152,CLDN3,TIMP3 |
| 4.356e-03 | -5.44 | Interferon Signaling | REACTOME pathways | R-HSA-913531 | 201 | 81 | 10285 | 3229 |
TRIM8,IFIT2,IRF7,NUP42,IRF8,ICAM1,SUMO1,PPM1B,STAT1,NUP107,EIF4A3,RNASEL,NUP37,ISG20,CAMK2G,EIF2AK2,KPNA2,BST2,IRF3,FCGR1A,IFNA10,JAK1,EIF4A2,IRF6,TRIM29,UBE2N,MT2A,IFNAR1,TRIM22,TRIM46,XAF1,PTPN1,NUP35,RPS27A,EGR1,IFNGR1,EIF4E2,TRIM6,TRIM5,IFI27,TRIM10,RIGI,NUP62,TRIM26,NUP153,IFNB1,IRF9,IFNA2,B2M,EIF4E,IFI6,SAMHD1,OAS1,IFNG,IFI35,TRIM21,IFNA13,JAK2,TRIM62,SOCS3,MX2,NUP50,ISG15,IRF2,TRIM34,TRIM35,STAT2,IRF4,PTPN11,UBA52,RSAD2,TRIM3,TRIM45,UBB,IRF1,EIF4E3,PIAS1,KPNA1,PML,TRIM68,MX1 |
| 4.361e-03 | -5.44 | DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2) | protein interactions | 3300 | 98 | 40 | 19454 | 5460 |
ESR2,SLC25A31,UBB,ACTB,PRNP,VPS26C,SPPL3,KCTD3,PSMA6,SRP14,STUB1,LMBR1L,DNAJB6,DNAJC7,SMAD4,CSNK2A1,MORF4L1,CUL3,MLF1,FKBP8,RPS27A,FBXO25,GRPEL1,NEDD8,RNF115,RLIM,BAG2,HSPA8,BIRC2,PML,LACC1,HDAC11,CTSA,CFTR,TUBA1A,ISG15,TRAF2,DDX39A,UBA52,TMEM231 |
| 4.365e-03 | -5.43 | HNRNPCL1 (heterogeneous nuclear ribonucleoprotein C like 1) | protein interactions | 343069 | 152 | 58 | 19454 | 5460 |
RPA2,LARP4B,HEXIM1,WTAP,PABPC5,ZC3H14,SHMT1,PRDX3,CCNH,RALYL,RBM22,RPA3,NGRN,NKAPD1,HMCES,RAB5A,FYTTD1,ELAVL2,CASC3,PPIG,H1-1,CUL3,HNRNPC,CUL2,MATR3,YES1,SH3BGRL,SRPK2,EIF2AK2,PHAX,PRKRA,UBE2I,MRPL13,TFCP2,CHMP4C,ESS2,PAIP2B,GNG10,CDC40,THRAP3,ASF1A,MEPCE,TFG,ZC3H11A,H2BC17,CRBN,HNRNPD,FGR,MOV10,COPS5,TRA2A,CAND1,PAIP1,SNRPA1,FAM118B,SRSF10,PRR3,RAC2 |
| 4.370e-03 | -5.43 | SLC35F6 (solute carrier family 35 member F6) | protein interactions | 54978 | 55 | 25 | 19454 | 5460 |
TMEM14B,CRELD1,MS4A7,AQP3,MGARP,TIMMDC1,SLC35F6,SEPHS1,COIL,ACP5,SEC11A,TMEM106B,SERPINH1,OAT,PSMG2,ACP6,P2RY10,TOMM40,GPR17,KRBOX4,MYC,KIAA0232,ATP6AP2,RAMP3,FOLR1 |
| 4.370e-03 | -5.43 | GJB7 (gap junction protein beta 7) | protein interactions | 375519 | 55 | 25 | 19454 | 5460 |
NRN1,CSNK1G3,GNAZ,GNAQ,CNTN1,GNB4,PYGB,DLG1,CCNY,YAF2,SNAP23,EPHA2,AP2A1,ZMPSTE24,SPPL3,INA,YES1,SVIP,UBTD2,UBTD1,EFNA5,NCKAP1,HRAS,GNAO1,PPP2R5E |
| 4.370e-03 | -5.43 | NAA25 (N-alpha-acetyltransferase 25, NatB auxiliary subunit) | protein interactions | 80018 | 55 | 25 | 19454 | 5460 |
CACYBP,ZBTB2,LMBR1L,REG1A,REG1B,RIT1,UBE2H,SMAD4,FGFR1OP2,GPR17,NRBF2,AKAP1,SNAPC1,CXCR4,RPA3,THUMPD1,AP2S1,TAF2,PSMB7,RPA2,CHMP4C,MND1,RAF1,CENPM,NDUFA2 |
| 4.370e-03 | -5.43 | ERCC5 (ERCC excision repair 5, endonuclease) | protein interactions | 2073 | 55 | 25 | 19454 | 5460 |
GTF2H2,CDC7,DYRK1A,APEX1,CDC5L,CSNK2A1,ERCC3,PRPF19,HSPB1,DTL,BRCA1,EWSR1,CLK1,PCNA,RPL31,BCL6,MNAT1,CDK7,CCNH,WDR77,GTF2H4,MOB3C,TAF10,GTF2H5,RPA2 |
| 4.370e-03 | -5.43 | CEBPD (CCAAT enhancer binding protein delta) | protein interactions | 1052 | 55 | 25 | 19454 | 5460 |
UBE2I,EP300,SNAP23,RB1,CEBPG,EEF1B2,SMAD3,RIGI,FBXW7,CEBPE,TRIM26,HDAC3,SIAH2,CCDC85B,XBP1,XPO1,SOX2,ATF4,CREBBP,DRG1,TRIB1,POU1F1,NOL7,IDH2,SMAD4 |
| 4.370e-03 | -5.43 | ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase) | protein interactions | 221120 | 55 | 25 | 19454 | 5460 |
CSK,FBXO7,ASCC1,CCT2,GSK3A,PRMT5,TUBB,TCP1,TAB1,MATR3,SRPK2,DHX15,CCT5,EEF1A1,TUBA1A,CCT8,INPPL1,MAP1B,TRIP4,HSPA8,TRIM63,THRAP3,KRAS,HSPA5,ZDHHC17 |
| 4.378e-03 | -5.43 | CHAF1A (chromatin assembly factor 1 subunit A) | protein interactions | 10036 | 192 | 71 | 19454 | 5460 |
ADNP,SUMO1,ACTL6A,RBFOX2,GTF2I,MBD3,XRCC5,RPA3,SQSTM1,MIS12,YWHAZ,SPOP,DSN1,MYC,CREBBP,NONO,SMARCE1,PRPF31,RBBP4,MAD2L2,APEX1,LRIF1,CBX5,CNOT6,ZNF330,CCNF,RPS3,RPS9,CDC7,EZH2,CHAMP1,CBX3,DMAP1,MTA2,SMARCB1,RBPJ,MTA3,ANP32A,SAP30,GFI1,H2AX,ASF1A,SERTAD1,H3C1,KRAS,PAX6,SSRP1,RIGI,PCGF6,MSH6,TOB2,ANP32B,CNOT6L,TOP2B,PABPC1,RBM3,PCNA,EWSR1,BECN1,BRD3,YWHAB,PIK3R1,YWHAG,BRMS1L,SUMO2,PRNP,SUMO3,MRPS9,GATAD1,LDLR,MYBL2 |
| 4.397e-03 | -5.43 | SDRFAMILY | prints domains | PR00080 | 40 | 20 | 5227 | 1528 |
HSD17B8,RDH12,DHRS4,DHRS3,DHRS11,SDR16C5,RDH11,HSD17B10,DECR2,HSDL1,HSD17B3,DHRS7,CBR3,CBR4,HSD17B6,DHRS7B,RDH10,HSD17B1,HSD17B11,KDSR |
| 4.398e-03 | -5.43 | cell surface | cellular component | GO:0009986 | 896 | 296 | 19108 | 5553 |
BST2,PSEN1,CD226,CD34,S100A10,AQP4,RS1,MSN,CAV3,UPK1A,MIF,CLEC12B,CAPN2,PICALM,CCR4,IGSF21,CD9,ABCG2,CEACAM5,ATP1A2,SDC2,RC3H2,CD2,CD79B,PDCD1,TIRAP,ELSPBP1,PHB1,SEMA7A,GPC1,ATP5F1B,AMELX,SARM1,FCN2,APMAP,KCNJ3,SLC1A3,AAMP,SLC6A1,LPAR1,VEGFA,BMPR1A,EFNA5,ACKR3,HHIP,LRP6,TF,HYAL2,BMPR2,MRGPRX1,GRIA2,CXCL9,IL1A,B4GALT1,CLSTN3,GHR,SLC1A2,CD86,CD46,H1-1,LRRC24,GPIHBP1,ERP29,CHRNB2,IL15RA,GRIA1,EMP2,DPP4,CD248,VAMP5,EFNB1,TNR,CD28,CCR3,TNF,IL2RB,CD1C,CXCR1,PDIA3,CCR2,FZD4,CCR6,CNTFR,TLR4,CTLA4,TGFB3,IL2RG,IL13,CD274,ACHE,ACVR1B,PLG,LDLR,LPAR2,ICAM1,B2M,TLR2,CD63,CX3CR1,NPTN,CDH13,TYROBP,CLEC2B,CD4,TACR1,ABCB1,LILRB4,P2RY1,EPHA2,P2RY12,VAMP3,ITGAV,HFE,SDC4,CLIC4,LRFN3,HSP90AA1,CD36,CXCR6,TPBG,GLRA1,CXCR3,LILRB1,TNFSF18,AGER,TFRC,ANXA4,EPHA4,ITGB5,MET,PDCD1LG2,SELL,NDP,TLR8,FZD6,CD14,AZGP1,CCR1,ITGA2,IDE,TGFBR2,IZUMO1R,SFRP1,CTSK,KCNB1,DAG1,ABCC2,MBL2,KLRC2,LY6G5C,THY1,FCGR2B,CD59,SLC32A1,SLAMF9,EPO,LGALS3,FAM234A,KCNC1,AQP11,FOLR1,ALCAM,TFPI,HMGB1,NOTCH2,EGFL8,CLEC6A,CALR,WNT7A,CTSB,TSPAN15,CD1B,CFTR,CD83,PRNP,NECTIN2,CD1E,LY6G6C,LYZL6,MRC1,FAS,FOLR2,CD1D,HBEGF,PROM1,CLU,TMIGD1,FURIN,IL2RA,LRRTM1,TMX3,HSP90AB1,FASLG,TREML1,CD151,CXCR4,CD3G,PRND,MME,CD209,RER1,THBD,CD40,TSHR,NLGN1,CCR7,RAMP3,HCST,NLGN2,CFC1,FCGR2A,BTN2A2,HSPA5,ATP5F1A,CLEC9A,TAS2R16,SFRP4,CD47,GREM1,F2,LEPR,FGFBP1,CD99L2,CXCL12,CLDND1,CD58,KLRD1,HSPD1,CLEC7A,TNFRSF9,SLC38A1,CD200,TNFRSF14,NEO1,SLC1A1,CD1A,ASTN1,CX3CL1,L1CAM,FGF10,CRYAB,MYD88,SLC7A11,CTNND1,LRRC8A,ITGA6,CD40LG,ITGB8,HILPDA,ENPEP,KIT,FLOT1,PHB2,EPCAM,CD200R1,H2BC1,ADTRP,IL6ST,TLR3,ATP6AP2,TMEM123,SERPINA5,F10,FZD3,ENO1,ASIC1,ATP5IF1,CD80,CXCL10,ADIPOQ,PPFIA2,FERMT2,EGFL7,FCGR1A,LAMP3,GPC4,HSPA8,SLC6A2,IL12B,RGMA,MOG,ADAM21,PCSK9,USP14,GPR37,FCER1G,CD38,BACE1,HM13,LYPLA1,SLC6A3,IRAK4,MICB,WIF1,CCR5,RALA |
| 4.399e-03 | -5.43 | HIRA (histone cell cycle regulator) | protein interactions | 7290 | 149 | 57 | 19454 | 5460 |
FABP5,NKX3-1,HMGA1,MOV10,ZCCHC10,PPIB,CSTA,HNRNPD,OAS1,BAG2,KRAS,H3C1,RBBP7,TRIM63,ASF1A,RUVBL1,TOP3B,MAX,RANBP1,SP4,E2F4,EGR2,JUN,SPRR1B,SMARCB1,IRF2,CTTN,UBN1,ELK3,CALML5,UBE2I,RBBP4,ESR2,TRAF1,HNF1B,MYC,GSTK1,CUL3,SAMHD1,BTF3,AR,MECP2,PML,FOS,HSPA8,TIFA,H2BC12,EP300,GTF2I,STAU1,MEF2A,H1-5,CCNA2,KLF3,RPA2,E2F6,CDAN1 |
| 4.405e-03 | -5.43 | endoribonuclease complex | cellular component | GO:1902555 | 35 | 18 | 19108 | 5553 |
RPP14,PRKRA,AGO1,HSD17B10,POP7,RPP25,DROSHA,TSEN34,RPP21,CLP1,POP5,TSEN54,DHX9,DGCR8,DICER1,TSN,RPP25L,TSNAX |
| 4.411e-03 | -5.42 | RASSF1 (Ras association domain family member 1) | protein interactions | 11186 | 101 | 41 | 19454 | 5460 |
EPHA2,LRP6,ID1,STK11,TUBG1,FBXW11,NDUFV2,XPO1,STK4,E4F1,SUV39H1,AKT1,MYC,MAP1S,SAV1,CDC20,MDM2,SMURF1,STK3,FZR1,TUBB,GRM1,CDK6,HRAS,MAP2K6,MET,VAPB,KDELR2,MAP2K3,EXOSC8,RAF1,CDK4,SKP1,NF2,HUWE1,KDM1A,TGFBR2,TERT,MAP1B,RHOU,ATP2B4 |
| 4.411e-03 | -5.42 | GUF1 (GTP binding elongation factor GUF1) | protein interactions | 60558 | 101 | 41 | 19454 | 5460 |
HSCB,TNF,IMMP2L,MRPS7,AMACR,EXD2,NGRN,OSTM1,COX8A,GFM1,HINT2,PDHA1,MTRES1,MRPL11,METTL15,MGARP,PARL,MALSU1,TACO1,SSR2,SSBP1,FAHD1,GATD3,PSMD14,CHCHD1,AGR2,SMAD4,DNAJC19,MRPS26,PFDN5,PMPCA,FAM174A,LAMP2,GRSF1,MTG2,AUH,MICB,MYC,MTRF1,TUFM,P2RY10 |
| 4.411e-03 | -5.42 | WDR44 (WD repeat domain 44) | protein interactions | 54521 | 101 | 41 | 19454 | 5460 |
ILF2,TMEM174,FGFR1,RPA2,VAPB,KIF2A,SEC62,FBXL19,PPP1CB,MREG,TP53,STX7,TGFBR2,PDHB,LSM4,EMC8,KRAS,SLC31A1,DHX16,IGF1R,SLC35F2,RAB5A,EP300,RHOB,PIP4K2C,TEX19,MCM3,CSNK2A1,RAB11A,SEC13,RAB11B,VIRMA,MANSC1,ACTB,OSBP,CX3CL1,SPINT2,SEC61B,TMEM74,HRAS,PTPN1 |
| 4.411e-03 | -5.42 | KGD4 (alpha-ketoglutarate dehydrogenase subunit 4) | protein interactions | 92259 | 101 | 41 | 19454 | 5460 |
RHOG,SNRNP70,CHCHD1,TMEM70,MRPS26,MTRF1,AUH,MTG2,GRSF1,PMPCA,HDAC6,TUFM,EIF4H,SIAH1,POLR2B,DBT,TACO1,SSBP1,CCDC90B,DLST,GATD3,PDHA1,GFM2,MTRES1,MRPL11,E2F4,DDX39A,AURKAIP1,METTL15,GJB1,HSCB,OGDHL,FASTKD5,IMMP2L,CRYZ,NGRN,HSPD1,EXD2,HINT2,GFM1,COX8A |
| 4.411e-03 | -5.42 | RAB13 (RAB13, member RAS oncogene family) | protein interactions | 5872 | 101 | 41 | 19454 | 5460 |
UBL4A,TUBA1A,MAP1LC3B,EZH2,RPA2,CA14,GDI2,TSPAN3,PDE6D,RPA3,EXD2,FLCN,RAB13,HSPA8,KRAS,SLC31A1,RNF115,SRPRB,ATG4A,DUSP19,RAB8B,MYC,LAMP2,FAM174A,RAB11A,CUL3,BTF3,LAMP3,SMAD4,TLR9,RHOB,POU5F1,HRAS,S1PR4,DUSP6,ARL4D,COPE,RAB1B,APLNR,WIF1,RABIF |
| 4.411e-03 | -5.42 | FAM171A2 (family with sequence similarity 171 member A2) | protein interactions | 284069 | 101 | 41 | 19454 | 5460 |
LMBR1L,RAB35,ZNF174,KTI12,GJA1,TMEM74,NRSN1,CX3CL1,PRDX2,RHOJ,TNFSF18,DYNLL1,EGLN3,STX6,CAV1,SFN,YWHAG,YWHAH,GNG2,DNAJC5,LAMTOR1,NCR3LG1,YWHAZ,RHOB,NTRK3,EPHA2,STYK1,YWHAB,EFNB1,PSMA3,NTRK2,KRAS,EPHA4,TGFBR2,STX7,ARL6,RIGI,FLOT1,JPH4,FGFR1,GNAZ |
| 4.430e-03 | -5.42 | SPTLC1 (serine palmitoyltransferase long chain base subunit 1) | protein interactions | 10558 | 146 | 56 | 19454 | 5460 |
RHOG,SLC25A28,CDK12,ATP5MG,ADIPOR2,ORMDL3,EGLN3,ELK1,NUP35,FBXO32,PHB1,HSD17B11,LDLR,RPN1,MOB3C,NCSTN,DNAJC25,SRPRB,TOLLIP,IMMP2L,TMT1A,SLC16A1,SPOP,RHOB,VMP1,OST4,MYC,CUL3,MORF4L1,RAB14,ARMC6,RHOJ,DYNLL1,VIRMA,LMBR1L,CCNF,SEC61B,LMNA,RPA2,GTF2IRD1,ARCN1,PTAR1,PGRMC1,SEC62,CDC42,OTULINL,RND2,CFTR,ADRB2,NRBF2,ATG4C,RHOU,RPA3,TMEM106B,ORMDL1,DERL1 |
| 4.430e-03 | -5.42 | TARS1 (threonyl-tRNA synthetase 1) | protein interactions | 6897 | 146 | 56 | 19454 | 5460 |
ATG101,NIBAN2,MYC,NAA50,CIAO1,PAPOLA,CUL3,RIT1,UBE2H,BRCA1,LMBR1L,CCNF,VIRMA,NDN,EHD1,UBLCP1,RPA2,JUP,HDAC5,BAP1,DVL2,RPA3,PML,UGP2,UFL1,GPC1,FBXW7,RPL4,VPS26A,DNAJB2,DNAJC7,HNRNPD,HSPB1,AGR2,TRAF6,CORO1C,PREP,EIF4E2,ARL10,GFPT1,ISG15,EEF2,KBTBD4,CCT5,TP53,MOB3C,APEH,TFCP2,PRKAG1,CHMP4C,ZYX,RPS27A,SAR1B,HUWE1,DCP2,FARSA |
| 4.441e-03 | -5.42 | RPS6KA2 (ribosomal protein S6 kinase A2) | protein interactions | 6196 | 189 | 70 | 19454 | 5460 |
VIRMA,ALG5,FERMT2,RPL7L1,YES1,RANBP6,AP2M1,CSNK2B,NECTIN2,VAMP3,CREB1,BAD,UBE2H,SLC38A1,HSP90AA1,EPHA2,ELMO2,ATP1B3,NCAPG2,PKP4,SLC25A1,AKT3,CSK,CREBBP,PIK3R2,YTHDF1,YKT6,RPS15,DCTN3,DCTN6,FOS,MAP2K1,SLC12A2,FGFR1,CDKN1A,NOTCH2,EFHD1,CAV1,SLC38A2,MPP1,HNRNPL,CDCA3,SLC39A10,EEF1AKMT3,SPRED2,WDR6,SRPRA,AGPAT1,ECD,NME2,EIF3D,PPFIBP1,GRSF1,PIK3R1,PTGES3,STRADB,AHCYL1,SLC6A8,CTNND1,L1CAM,SNAP23,TRIM11,ACTR1B,KLHL25,ALPL,JUN,TP53,IPO8,TOP3B,MARCKSL1 |
| 4.441e-03 | -5.42 | ARID4B (AT-rich interaction domain 4B) | protein interactions | 51742 | 189 | 70 | 19454 | 5460 |
RBBP4,VIRMA,APEX1,PHF12,ELK3,ZNF330,ING2,CTSK,PSMD14,RPS26,SP1,SNX5,HNF1B,PIK3R3,NTAQ1,GGH,FBXW7,TGIF2LX,SAP18,MBD3,YAF2,MXD1,KLF3,LACC1,PAX9,ACTL6A,KLF12,PLEKHF2,FZR1,TOP1,BRMS1L,SHPRH,SLC25A17,KLF9,SIN3A,H2AZ1,COX4I1,MYBL2,EED,GATAD1,LDLR,LHX2,CSNK2A1,NT5C2,RBBP7,H3C1,PHF1,PAX6,HNRNPA2B1,TGIF2,KLF10,IRF8,EZH2,CDK8,MTA2,SMARCB1,HBP1,MAX,MTA3,INSIG2,ZNF704,PHF23,SOX2,ING1,AURKAIP1,H2AX,EGR2,ELF1,SOX9,SAP30 |
| 4.453e-03 | -5.41 | LRRFIP2 (LRR binding FLII interacting protein 2) | protein interactions | 9209 | 104 | 42 | 19454 | 5460 |
SNRNP70,VMP1,KARS1,IFI16,DPP4,MYC,PPP1CC,CTNNB1,HDAC6,BTF3,ACTB,TMOD3,SMUG1,DYRK1A,MYL12A,TMPO,CDK9,CTTN,CCNF,SH2D1A,CAPZA2,PSMC3,TMOD1,CRYGD,RAF1,ATG16L1,PSMC4,CFTR,MAP1LC3B,ISG15,STAU1,TRIM37,TNF,RNF26,CAPZA1,PSMB10,PIAS1,ATPAF2,DDX39B,MYD88,TMEM147,HSPA8 |
| 4.453e-03 | -5.41 | MYCBP (MYC binding protein) | protein interactions | 26292 | 104 | 42 | 19454 | 5460 |
FBXW11,YWHAZ,RC3H2,EIF5A2,MAPRE1,YWHAB,UBE2H,ZBTB38,NDC80,MORF4L1,MYC,YWHAG,CFL1,YWHAH,CPEB1,DYNLL1,CFAP91,FZR1,OCRL,CPNE1,VIRMA,EGLN3,UBB,HEXIM2,CORO1C,TPT1,SUPT5H,ARFGEF1,SUPT4H1,ELK4,DDX39A,ACTR1A,KDM1A,PTN,HSPA5,SSRP1,SELENOO,BAP1,UBE3A,AKAP1,CPNE2,RNF34 |
| 4.459e-03 | -5.41 | CC2D1A (coiled-coil and C2 domain containing 1A) | protein interactions | 54862 | 143 | 55 | 19454 | 5460 |
FGFR1,RPA2,CRYAB,TRIM36,SAP30BP,ATG16L1,STAU1,SLC31A1,FTL,STX7,RPA3,RAB5A,SQSTM1,RAB9A,BICD2,RHOB,LAMTOR1,RAB11A,H2BC9,RHOJ,ACTB,NDN,CAVIN2,ESR2,APEX1,ACP2,CCNF,SLC1A1,RAB4A,CHMP4C,TSPAN3,RAF1,TOP3B,KBTBD4,H2AX,THRAP3,RIGI,PTGES3,RPL31,MAP1B,RUVBL2,ZC3H7A,BRD3,H2AC14,YWHAH,CPEB1,COPS5,XPO1,DNAJC1,CEP19,LRWD1,CAV1,TMPO,ARL10,GJA1 |
| 4.459e-03 | -5.41 | BAZ1A (bromodomain adjacent to zinc finger domain 1A) | protein interactions | 11177 | 143 | 55 | 19454 | 5460 |
RBBP4,APEX1,SRPK2,RAN,ZNF330,FGFBP1,SPOP,MECP2,CCDC22,CHRAC1,SMAD2,UBE2H,SMARCA5,MYC,RAB2A,NUCKS1,MBD3,RPA3,XRCC5,CTBP1,RPA2,GRM2,FUT8,POLR1D,RAB1B,SUMO2,POLE3,H2AZ1,EED,TRAPPC10,TRAPPC2L,H2AC4,SMAD9,KPNA1,BRD3,HMGA1,BAZ1B,CSNK2A1,YWHAG,ARL5B,H3C1,RBBP7,SATB1,RAD21,RAB1A,EZH2,TRAPPC13,MTA2,NUPR1,B3GNT2,ZNF263,MAX,RAF1,H2AX,MAP1LC3B |
| 4.480e-03 | -5.41 | PALM (paralemmin) | protein interactions | 5064 | 72 | 31 | 19454 | 5460 |
CERS2,KRAS,FLOT1,STX7,RHOU,TMEM185A,RABGGTB,NUPR1,RND3,CENPM,TOP3B,DUSP22,DDX39A,RHOJ,ESR2,CAV1,DIRAS3,CYB5R3,RAB35,RAC2,GJA1,RHOB,FYTTD1,RHOG,MED21,LAMTOR1,RAB11A,DPP4,MTRF1,DNAJC5,TOMM40 |
| 4.480e-03 | -5.41 | RNF169 (ring finger protein 169) | protein interactions | 254225 | 72 | 31 | 19454 | 5460 |
ZNF330,H2AZ1,RPS3,QSER1,PRNP,ESR2,DYRK1A,APEX1,CUL3,HMGA1,MYC,DYRK1B,PPP1CC,CEP70,LMNB1,BRCA1,H2AC4,TRAPPC2L,NBN,PML,NUP50,FARSA,NUCKS1,ASF1A,TRIM37,H3C1,MDC1,CAPZA1,COIL,TUBB4B,CBX3 |
| 4.480e-03 | -5.41 | TACC2 (transforming acidic coiled-coil containing protein 2) | protein interactions | 10579 | 72 | 31 | 19454 | 5460 |
TMPO,ESR2,VIRMA,SLAIN2,PTPN1,TUBA1B,HSD17B11,CLVS2,SEC61B,SOSTDC1,YWHAZ,PAXX,MAP4,MAPRE1,KXD1,ATG9A,CREBBP,PPP1CC,TOMM20,FKBP8,RNF41,RIGI,PML,EP300,DERL1,TUBB4B,SMARCB1,HECTD1,PIH1D1,DDX39A,BORCS6 |
| 4.480e-03 | -5.41 | NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2) | protein interactions | 4718 | 72 | 31 | 19454 | 5460 |
TACR1,TMEM126B,TMEM185A,NDUFB5,TSPAN15,HSCB,COA1,DNAJC30,YIPF3,LPAR6,TIMMDC1,MTCH2,NDUFA2,NDUFA12,CRELD1,GPR34,RPA2,NDUFS6,FUT1,IL2RA,NDUFA1,NDUFAF4,CSGALNACT2,NDUFV2,KDSR,NDUFB7,COX6B1,NDUFB6,NDUFB10,NDUFB8,CHCHD4 |
| 4.480e-03 | -5.41 | NMT2 (N-myristoyltransferase 2) | protein interactions | 9397 | 72 | 31 | 19454 | 5460 |
VIRMA,PSD2,ARF6,GFOD1,TMED9,MGST3,CSNK2B,ANXA4,PHB1,PHETA2,ARL11,DEFB1,LRATD1,H2AC4,PPP1CC,CSNK2A1,RFTN2,HPCA,BTF3,TUSC2,PRPS1,SMN1,RP2,SLC31A1,EP300,ANXA7,ZNRF1,RPA2,ACBD6,TP53,MARCKSL1 |
| 4.480e-03 | -5.41 | SNF8 (SNF8 subunit of ESCRT-II) | protein interactions | 11267 | 72 | 31 | 19454 | 5460 |
CLP1,RIT1,SMAD2,WDR12,POLB,NIF3L1,GTF2E1,PRMT6,PSMD3,APEX1,TRIM54,GTF2F1,TSG101,SMAD3,VAC14,JCHAIN,MTA2,METTL14,RPA2,BPIFB1,TNPO2,NUDCD3,CENPM,ADORA1,NAA15,VPS28,KRAS,KDM1A,TTC1,DVL2,RPA3 |
| 4.480e-03 | -5.41 | ZDHHC23 (zinc finger DHHC-type palmitoyltransferase 23) | protein interactions | 254887 | 72 | 31 | 19454 | 5460 |
PIK3CA,RPS11,PRKCA,GNAQ,TP53,RPSA,PPARA,GNG10,ETF1,RP2,IGF1,VPS28,FLOT1,GNA11,CCNY,CPNE2,RING1,PDF,RALB,AKT1,VPS26A,SNX2,YES1,SNX1,UBTD2,SRC,LORICRIN,HRAS,SIN3A,TSG101,RRAS2 |
| 4.480e-03 | -5.41 | FAM234B (family with sequence similarity 234 member B) | protein interactions | 57613 | 72 | 31 | 19454 | 5460 |
SCGB1D1,ORC5,PLPP4,DHRS7,CSGALNACT1,LAMTOR1,ATP1B3,B4GALT1,RAC2,SEC61B,LMBR1L,PTPN1,LAPTM4A,STX6,CLRN2,ANKH,NRSN2,TMEM59,DDX39A,TNPO2,GINM1,SEC22B,BET1,STX12,LEMD3,HBB,TMX4,RAB4A,ITM2B,SLC25A51,ST8SIA4 |
| 4.481e-03 | -5.41 | TTYH1 (tweety family member 1) | protein interactions | 57348 | 296 | 104 | 19454 | 5460 |
MBLAC2,LRRC8C,KCNJ8,ENTPD4,TMEM179B,PIGA,CGRRF1,RETREG3,GPR89A,ABHD12,GPR37,LRRC8A,TAMM41,SPCS1,CCDC167,SEC62,GLRB,GJC1,BET1,GOSR2,RDH12,LMBRD2,ABCB1,TMEM115,SLC35F2,MIA2,STX7,PXMP2,CERS6,GOSR1,TMEM164,ITPRIPL2,GJA1,STX5,TLCD4,CYB5R1,MACO1,DCAKD,ABHD6,TMEM39A,ADCY3,EFNB1,SEC11A,TMEM87A,NDUFB5,GPAA1,USP30,COA1,TMEM60,PGAP4,RETSAT,SMPD2,SNX14,PHTF2,SMAD5,ST7,HACD2,CHST7,TMEM219,CPSF4,SLC35F6,FUT8,KCNJ11,LEMD3,PIGW,SLC12A2,USE1,GOLGA5,SPCS2,ABCB9,LRRC8D,ORMDL1,CERS2,LPAR1,BVES,DHRS7,FAR2,LRRC8B,FITM2,EXT1,ATP8A1,HACD3,PTPN1,ACSL4,SLC25A17,DNAJC1,SLC29A1,ALG11,POMT2,CERK,TMEM94,SLC35F1,BSCL2,STX18,GALNT12,BCAP29,MAN1A2,ATP2B4,TUSC3,FKRP,RIGI,LPCAT3,DNAJC30,B4GALT7 |
| 4.484e-03 | -5.41 | mitotic cell cycle process | biological process | GO:1903047 | 511 | 178 | 18204 | 5365 |
CHMP5,MAPRE1,PPP2R1A,CDKN1B,CUL3,RAN,KLHL22,NBN,CCNB1,CCNA2,CHMP4C,RACGAP1,NDC80,EFHC1,MNAT1,RAD21,CUL2,EZH2,VRK1,HSPA8,CHMP1B,NDE1,TBCE,FBXL7,MCM3,CDK6,EPS8,CKS1B,MAP1S,TP53,ARF1,CDC23,LCMT1,TAF10,MDM2,SKA2,DTL,CCNY,BIRC5,PAFAH1B1,CHAMP1,MCM4,VPS4A,SKA1,KIF3B,CACUL1,TUBG1,ROCK1,NAE1,CCNF,EXOC3,NEK2,PRKCA,GJA1,PPM1D,CDK4,PIAS1,EXOC8,AKAP8L,EXOC5,RAB35,USP16,DCTN6,CDKN1A,PML,NUP62,EXOC2,LSM14A,IK,RB1,UBXN2B,FBXW11,CRADD,RPL24,NSFL1C,TOPBP1,ACVR1B,NUF2,RHOU,RANGRF,PPME1,RINT1,RHOB,HINFP,POLDIP2,BCCIP,ROCK2,SPTBN1,RAB11A,RPA2,TMOD3,FBXO31,BRCA1,MYBL2,TAF2,EXOC1,HDAC3,DNM2,MDC1,SEPTIN6,PLCB1,RPS27L,CKS2,UBE2S,ARPP19,CDKN3,ANAPC2,UBE2I,WNT10B,USP8,TNKS,PAX6,RBBP8,CHMP2A,MAD2L2,NCAPG2,CNTROB,BABAM1,CHMP2B,PIM2,TPD52L1,CDK1,PSRC1,TRIM36,UBE2A,MAP4,CFL1,TENT4A,NAA50,BTN2A2,MTA3,SPRY1,PHF13,KLHDC8B,MCM6,ZNF207,CHMP1A,CDC20,FZR1,RTKN,ID4,IER3,STAMBP,EIF4E,MYC,BUB3,ENKD1,KIF2A,REEP4,BANF1,CCND1,PSMG2,BECN1,MAD2L1,MCPH1,NABP1,MIS12,SKA3,PRKCB,CDK5RAP3,NOP53,H2BW1,PPP3CA,CDC7,RPL26,SNX33,VPS4B,GINS3,RTF2,SNX18,ABCB1,SMC4,REEP3,CCND3,CCNI,PCNA,SPC24,FGF10 |
| 4.484e-03 | -5.41 | RPS6KB1 (ribosomal protein S6 kinase B1) | protein interactions | 6198 | 140 | 54 | 19454 | 5460 |
BICD2,RPS6KA4,SERPINH1,HSP90AA1,STK11,AKT1,AKT3,FBXO7,RHEB,RNF40,STAT1,ESR2,UBA3,APEX1,SRC,NR1I2,PPP5C,GRIA1,RPS12,CSNK2B,MXD1,JUP,CDK1,RPA2,CTBP1,EIF4B,SYK,ATG16L1,CDC42,GTF2I,EIF4E,RPA3,EP300,SQSTM1,DDX5,TERT,PSMD10,AGR2,CSNK2A1,XPO1,HNRNPL,MXI1,MDM2,RB1,PIK3CA,CCT5,TBK1,UBL4A,KIT,POLDIP3,CAPZA1,RNF20,AKT2,NAE1 |
| 4.487e-03 | -5.41 | IQGAP2 (IQ motif containing GTPase activating protein 2) | protein interactions | 10788 | 107 | 43 | 19454 | 5460 |
BAP1,S100B,ZYX,RPA3,SQSTM1,KPNA2,KRAS,SKP1,TRIM52,MYL12B,RAF1,H1-5,CDC42,TSHR,PPP2R1A,ACTR2,RPA2,MYL6,NFKBIB,RAB35,CCNF,ACTB,RHOJ,TXNDC12,ARF6,CAV1,GNAI2,RABIF,VIRMA,CUL3,MYC,NFKB1,MAP3K14,BTF3,HSPB8,FBXW11,RHOB,ASIC2,LAMTOR1,RHOG,IKBKB,AKAP8L,HAX1 |
| 4.487e-03 | -5.41 | NOB1 (NIN1 (RPN12) binding protein 1 homolog) | protein interactions | 28987 | 107 | 43 | 19454 | 5460 |
CUL3,MYC,MAP3K14,KLHL22,DDRGK1,RIOK2,XPO1,DCAF4,FTSJ3,RIT1,UBE2H,DRG1,DCAF11,RPS2,COP1,METAP2,POLR3B,PRNP,CGAS,DYNC1I2,RPS16,FZR1,RPL10,EGLN3,RBM42,TOP3B,RPS14,CSNK1E,ATG16L1,TULP3,POLR1D,ARCN1,HBP1,PNO1,RPA3,EP300,STAU1,HSCB,PSENEN,KRAS,G3BP2,FTL,RPS13 |
| 4.487e-03 | -5.41 | RPL39 (ribosomal protein L39) | protein interactions | 6170 | 107 | 43 | 19454 | 5460 |
PSPC1,IRF2,METAP2,RPL37A,SEC61B,RPS9,SMURF1,RPL19,ESR2,MYC,FTSJ3,VMP1,RIT1,RPS15,SYK,CDK7,KLF12,EMC9,E2F6,FOLR1,RPL9,DUSP6,PHB1,RPL32,RPL35A,RPS16,CDC5L,ZBTB2,ENY2,ATG7,CPEB1,DRG1,RPL23,HNRNPA2B1,RBM3,PABPC1,TNF,KRAS,H3C1,RBBP7,MEPCE,RPS4X,SOX2 |
| 4.487e-03 | -5.41 | ERRFI1 (ERBB receptor feedback inhibitor 1) | protein interactions | 54206 | 107 | 43 | 19454 | 5460 |
SFN,YWHAZ,UBASH3B,ZMAT2,GTF2H2,TUBA1B,SRC,PSMB6,ACTB,TUBB,CDC42,IL2RG,TIMP4,AOX1,HSPA8,DCTN6,COPS5,XPO1,YWHAG,YWHAH,PPM1D,CRHBP,YWHAB,RB1CC1,SHC1,SKIC8,MFSD5,ACTA2,NPC2,EGLN3,PPIA,SPPL3,H2AX,TUBA1A,TMEM59,NEU1,ERRFI1,GNPDA2,TMEM165,PCNA,STX8,RAB18,RPS27A |
| 4.515e-03 | -5.40 | KIT (KIT proto-oncogene, receptor tyrosine kinase) | protein interactions | 3815 | 110 | 44 | 19454 | 5460 |
PSMD14,SPRED1,GRB10,PTPN11,PIK3R3,SOCS5,IFNAR1,STAT1,STAT5A,YES1,SRC,JAK2,SLA2,HSP90B1,PRKCA,SYK,HSH2D,PIK3R2,STAP1,IRF3,PRKCB,SHC1,NCK1,CD9,CBL,FGR,PIK3R1,CD81,GRAP,SHC3,CISH,SPRED2,CD63,SH2D1A,PIK3CA,CTLA4,BMPR2,GRAP2,CRKL,TP53,SOCS3,KIT,SOCS2,PIK3CG |
| 4.515e-03 | -5.40 | mediastinum | COSMIC cancer mutations | mediastinum | 38 | 19 | 16828 | 4835 |
JAK2,PTPN11,AKT1,CDKN2C,IDH2,FBXW7,MET,KIT,CTNNB1,MYD88,EZH2,PIK3CA,PIK3R1,IDH1,HRAS,KRAS,TNFAIP3,GNAQ,MAP2K1 |
| 4.515e-03 | -5.40 | epithelioid | COSMIC cancer mutations | epithelioid | 38 | 19 | 16828 | 4835 |
PTEN,TERT,PIK3CA,IDH2,FBXW7,AKT1,TP53,RB1,KIT,GNA11,CTNNB1,SMAD4,SF3B1,SS18,BAP1,GNAQ,IDH1,HRAS,KRAS |
| 4.535e-03 | -5.40 | ERP29 (endoplasmic reticulum protein 29) | protein interactions | 10961 | 113 | 45 | 19454 | 5460 |
TSPO2,DNAJB9,MYEF2,HSPB1,AGR2,TMBIM6,CALR,DPP4,SLC38A7,RIGI,HUWE1,CTNNBL1,DNAJC30,ADIPOQ,ERP29,OTULIN,TFRC,HSPA13,CHMP4C,H2AX,NRM,B3GNT2,RAF1,CTSB,SEC61B,SGTA,CCNF,CYB5R3,CALU,DNAJC10,EXOC5,SLC35B4,MYC,CIAO1,HSPA5,GTF2I,DESI1,AKAP1,BAP1,DNAJC3,TMEM106B,LMNA,WWP1,UBLCP1,EDEM3 |
| 4.535e-03 | -5.40 | LDOC1 (LDOC1 regulator of NFKB signaling) | protein interactions | 23641 | 113 | 45 | 19454 | 5460 |
CCDC85B,TTC23,PRPF31,THAP7,ATF4,FAM193B,LMO2,ZNF250,MYC,FAM107A,SCNM1,JAK2,FCHSD2,RPP25,CEBPE,FAM161A,MFAP1,SDCBP,ZMYM6,FAM50B,RAB29,AATF,ATP6V1G1,MBD3,LDOC1,FXR2,SETD5,TSNAX,ZNF688,CDC5L,PEG10,PRPF18,PLEKHF2,PPP1R18,MEAF6,IKZF5,HGS,SMARCB1,ZFP1,ENKD1,AP1M1,POLL,CTNNBL1,PSMA1,ZBTB16 |
| 4.535e-03 | -5.40 | VAT1 (vesicle amine transport 1) | protein interactions | 10493 | 113 | 45 | 19454 | 5460 |
EIF2S2,MSN,PLP1,SSH3,PSMD1,CARS1,RAB11A,LAMTOR1,YWHAZ,TTC1,AKAP1,DVL2,BAP1,SOD1,RPA3,OTULINL,RPA2,HRAS,CACYBP,SPPL3,FZR1,COPS5,LAMP3,KARS1,LAMP2,WDR12,RHOG,AGR2,ERO1A,RUVBL2,RAB1A,PABPC1,PSME1,SAR1B,KRAS,RBBP7,RUVBL1,KPNA2,H2AX,SOX2,TRAF2,RAF1,MTCH2,TP53,EZH2 |
| 4.541e-03 | -5.39 | DENND4C (DENN domain containing 4C) | protein interactions | 55667 | 131 | 51 | 19454 | 5460 |
MAP3K21,CSK,RAB2A,FAM110B,RAB11A,SFN,NTRK3,LAMTOR1,YWHAZ,FBXW11,GSK3A,PHF21A,VIRMA,SIPA1L1,CNPY3,ATG16L1,INPP5E,CSNK1A1,AGAP1,RPA2,FGFR1,FAM53C,HSPA8,RAB9A,RAB5A,RTKN,STX7,KDM1A,HSCB,XPO1,YWHAG,LAMP3,YWHAH,LAMP2,MED4,YWHAB,CAMSAP2,TIAM1,GJA1,RAB35,EIF4E2,STX6,CAV1,ARF6,KCTD3,KIF1C,STARD13,CDK8,RAB4A,TESK2,SRSF12 |
| 4.541e-03 | -5.39 | ARG1 (arginase 1) | protein interactions | 383 | 131 | 51 | 19454 | 5460 |
METTL14,RPA2,JUP,E2F6,NUDT3,CDC42,AZGP1,CDSN,ARG2,DDX39B,RPA3,HSPA8,YWHAZ,UBE2H,SETD7,COP1,MYC,ATG101,RBBP4,CCNF,CFAP298,GSK3A,CBX3,EZH2,APTX,RNF8,SELENOF,CCR1,TP53,B3GNT2,MAX,TBK1,SPRR1B,FCF1,TRIM37,RAD21,PCGF6,FLOT1,POC1B,CSTA,ADIPOR2,PTDSS1,ERCC3,HNRNPA1,PRNP,POLR2L,SRSF1,FABP5,CD274,MCL1,WDR82 |
| 4.550e-03 | -5.39 | S100A10 (S100 calcium binding protein A10) | protein interactions | 6281 | 116 | 46 | 19454 | 5460 |
FLOT1,DUSP19,DNAAF10,SRPRB,TRIM37,S100A10,TNF,ABCE1,MAEA,MOB3C,CHMP4C,PPIF,FAF2,OR4N2,RAF1,CDK9,SUMO2,PLG,PPFIA3,RPL12,SIN3A,RPL10A,PDYN,ZCCHC9,HDAC6,USP2,SLC25A46,HSPA8,RPA3,BAP1,ELMOD1,ANXA7,LUC7L3,RPA2,ZNF428,VIRMA,DYRK1A,TAB1,RPL10L,CTSB,CCNF,BAD,UBE2H,CBR3,ZMPSTE24,MYC |
| 4.550e-03 | -5.39 | ZNF131 (zinc finger protein 131) | protein interactions | 7690 | 116 | 46 | 19454 | 5460 |
DPY30,HSPB1,AGR2,XPO5,GATAD1,GNB3,FBXO31,NTMT1,KLF9,SNRPD3,ELF1,CBX3,CDK8,EXOSC3,RAB6B,HINT1,TRAFD1,PHF1,ZBTB45,PDE12,KPNA2,NRGN,BACH1,RUNX1,MTPN,KPNA6,MORF4L1,MRM2,CUL3,ZMYM2,ZBTB18,SEC61B,SENP5,PHF12,CREB1,ELK3,APEX1,SNRNP40,MORN4,RAB6A,KLF12,KLF3,BAP1,HCFC2,NHP2,RBM22 |
| 4.550e-03 | -5.39 | ARL5A (ADP ribosylation factor like GTPase 5A) | protein interactions | 26225 | 116 | 46 | 19454 | 5460 |
LEMD3,ACACA,GOLGA5,STOM,FUT8,CCDC186,MAVS,LMNB1,CCT2,LAMTOR1,PCCB,GORASP2,RAB2A,CBX5,B4GALT3,RAB3C,TRAPPC13,STIM1,EZH2,CBX3,LBR,CTDSP2,MARCKSL1,B3GNT2,KPNA2,SRPRB,ARL5B,SNAP23,PC,CCT8,RAB1A,HNRNPD,CBL,TRAPPC2L,RAB5C,RELL1,HSP90AB1,CCT7,SLC38A2,TMPO,TCP1,RAB1B,TRAPPC10,CDCA3,PHB1,SRPRA |
| 4.587e-03 | -5.38 | aminoglycan biosynthetic process | biological process | GO:0006023 | 69 | 31 | 18204 | 5365 |
CHPF,CHST9,ABCC5,NDST3,CHST13,B4GALT4,B3GNT2,HEXA,HS3ST1,NDST1,GLCE,ST3GAL1,B4GAT1,CSGALNACT1,B4GALT7,EXT1,CHST2,CHST1,HAS3,CSGALNACT2,PXYLP1,IL1B,ANGPT1,ST3GAL4,UST,CHPF2,HS3ST3A1,CHST7,UGDH,ST3GAL2,CHST11 |
| 4.594e-03 | -5.38 | dendrite | cellular component | GO:0030425 | 620 | 210 | 19108 | 5553 |
KCNJ2,SLC1A1,CDK5,SRC,FEZ1,CRYAB,STAU1,GPHN,HOMER1,CHRM5,L1CAM,GABRA1,CTNND1,NTF4,TRAK2,MOB4,GLRX5,MAP1B,IL6ST,RAB27A,DRD1,ELK1,TMEM266,KCNH1,BGLAP,GNAI2,GNAO1,STAT1,KIF3B,TMEM185A,ABITRAM,CD2AP,ATP6AP2,FZD3,NTRK2,GRM1,PPFIA2,HSPA8,LRRC4,NQO1,CHRM4,ADORA3,CHRM1,GPR37,UHMK1,BACE1,KPNA1,SLC32A1,HOMER3,GNG3,THY1,FCGR2B,RBM3,HTR5A,HTR1F,ZC3H14,ELAVL4,KCNC1,SYNDIG1,ALCAM,CDK5R1,MAX,COMT,SLC6A6,SYT4,SLITRK2,CTTN,PRNP,ATF4,ASIC2,OPRK1,BRINP3,CLU,TMEM108,YKT6,PPP2R1A,ABHD13,ERO1A,GABRG2,TRIM3,FUBP3,PCSK2,LYNX1,PDE4B,HSP90AB1,C9orf72,NDFIP1,GRM2,GLRX2,SLC4A10,AMIGO1,SRSF10,MME,PDLIM4,HRH3,BRINP2,NLGN1,SLC8A1,RCVRN,KIF1C,NLGN2,CACNG3,HTR1A,HRH2,SLC4A8,CHRM3,FGF13,GNAZ,HDAC6,CCR2,FZD4,PSD2,BRINP1,DRP2,PPT1,CRHBP,DYRK1A,EPHB6,HPCA,CAMK2N1,BMPR1B,KCND3,TACR1,CPLX2,AZIN2,JPH4,LRFN3,P2RY1,GABBR1,GNG13,BAG2,TACR3,IFT57,ADNP,TPBG,GLRA1,PNOC,NCDN,HSP90AA1,PRSS12,LGI1,EPHA4,GPM6A,NGDN,GABRA2,ROGDI,ADORA1,CTTNBP2,ARF4,ADCY2,KCNB1,DLG4,EIF4A3,HTR2A,USP8,TRAPPC4,LYPD6,CAPN2,LHFPL4,CASC3,PPP1CC,SLC38A2,IFT52,RPL28,PSEN1,ATXN1L,ELFN1,TIAM1,ATP1A2,SNX14,CPEB1,PPP3CA,LAMP5,GLRB,ATXN10,RGS7BP,OPRM1,MAP1S,NSG1,KCND2,CDC42,NEGR1,KCNA2,GCHFR,TXNRD2,LPAR1,PTEN,BECN1,IGF2BP1,SARM1,ABHD17A,KCNIP2,SIPA1L1,KLHL1,OPHN1,BMPR1A,PDYN,RAB5A,CCN3,BMPR2,GRIA2,MTMR2,CLSTN3,MT3,GSK3A,GNB3,SOD1,UCN,GRIA1,ABHD12 |
| 4.629e-03 | -5.38 | VTN (vitronectin) | protein interactions | 7448 | 180 | 67 | 19454 | 5460 |
ADTRP,EED,HP1BP3,RBM5,SRSF1,SRSF10,DHX15,CDC5L,ATXN10,SNRPA1,BUD31,HDAC6,COPS5,CSNK2A1,DDRGK1,CRADD,RNF14,PRPF19,TGFB2,CD247,AGPAT1,RHOG,SEPTIN7,DHX9,PRDX4,LPCAT3,RAF1,INSIG2,DLG3,CDK4,SMARCB1,ITGB8,CCR1,ITGB5,RPS11,ILF2,CHMP4C,IK,TRMT11,SMU1,VEGFA,SF3B6,SMURF1,ESR2,DEK,CTSB,RPL13A,SLC6A1,TFDP2,LACRT,SF3B1,PRKCB,DDX5,SAP18,SLC37A4,UFL1,CNPY3,CFTR,HACD2,SF3A1,LNX2,PRKCA,CKS2,LUC7L3,USP39,ARMCX3,ISOC1 |
| 4.629e-03 | -5.38 | LUZP1 (leucine zipper protein 1) | protein interactions | 7798 | 180 | 67 | 19454 | 5460 |
MED4,SSX2IP,YWHAB,CAMSAP2,HSPB1,KXD1,NDC80,YWHAG,YWHAH,CGAS,CNTROB,MGME1,EZH2,DISC1,CAPZA2,CHMP4C,ACTR2,NUPR1,RAF1,ISG15,SOX2,KIF2A,G3BP1,TOLLIP,TRIP4,ZYX,BAG2,YWHAZ,BRCA1,BICD2,SP1,MAPRE1,MYC,SFN,BTF3,GALE,DAPK3,RPGRIP1L,ACTB,MAD2L1,DYRK1A,ESR2,VIRMA,CCNF,CTTN,TNFRSF1B,RMDN3,GSK3A,PHF21A,PTEN,RPA2,SCLT1,TRIM36,PPP1CB,BORCS6,FXR2,KDM1A,STAU1,FBXW7,HSPA5,BAP1,RPA3,LCA5,DDX39B,PML,HSPA8,SQSTM1 |
| 4.632e-03 | -5.37 | EAPP (E2F associated phosphoprotein) | protein interactions | 55837 | 75 | 32 | 19454 | 5460 |
PRPF19,ZCCHC10,INSYN1,SNRPB,TPM3,DDX23,KIAA1143,ECD,TNFAIP8,SLX1A,SNRPD2,SNRPD1,SNRPD3,ACTB,EGLN3,CDC5L,WDR83,DHX38,SNRPN,DDX39A,CD2BP2,USP39,SNRPE,SLU7,NCDN,PRPF4,RUVBL2,UBE3A,TSSC4,RUVBL1,FTL,SNRPG |
| 4.632e-03 | -5.37 | ARL5B (ADP ribosylation factor like GTPase 5B) | protein interactions | 221079 | 75 | 32 | 19454 | 5460 |
TIMMDC1,RRM1,LBR,LPAR6,GOLGA5,EZH2,ACACA,LEMD3,TRAPPC13,CCT8,RAB1A,MAVS,AKAP14,GRPR,SRPRB,RAD21,RAB5C,RAB2A,FNDC11,SLC30A5,GORASP2,CHRAC1,PDCD1,TRAPPC2L,SMAD4,ATP1A3,SYP,SLC20A1,TNFRSF9,EDNRA,EED,TMPO |
| 4.632e-03 | -5.37 | KLHDC2 (kelch domain containing 2) | protein interactions | 23588 | 75 | 32 | 19454 | 5460 |
UBE2M,CCM2,EZH2,NUDCD3,SELENOK,CCT5,PFDN1,NEDD8,GCNT3,BAP1,YWHAB,PFDN2,HNRNPD,YWHAZ,CCT2,ELOC,YWHAH,YWHAG,PFDN5,SFN,SELENOS,CUL2,RAB2A,APEX1,DCUN1D1,TCEAL1,SDHAF2,FBLN5,EEF1AKMT3,FEZ1,FAIM,STUB1 |
| 4.633e-03 | -5.37 | negative regulation of cation transmembrane transport | biological process | GO:1904063 | 94 | 40 | 18204 | 5365 |
TLR9,MIR208A,MIR30D,PLN,PPP3CA,GSTM2,VDAC1,TMBIM6,GSTO1,OXSR1,MIR208B,CAB39,HECW1,MIR212,ATP1A2,PPIF,DRD3,MIR153-1,PPP3R2,MIR200C,EPO,FKBP1A,CLIC2,KCNAB1,CAV1,MIR24-1,ISCU,PCSK9,MIR192,FKBP1B,PRKCE,SESTD1,MIR1-1,MIR448,MMP9,GPR35,SUMO1,CRHR1,SRI,CAV3 |
| 4.649e-03 | -5.37 | CRACR2A (calcium release activated channel regulator 2A) | protein interactions | 84766 | 58 | 26 | 19454 | 5460 |
IZUMO1,EIF1AX,ATG16L1,PNMA5,OIP5,RAB3B,ASB3,CERS6,DDIT3,LAMTOR1,CCHCR1,CDC23,MDFI,USP2,RAB11A,FAM156A,SPPL3,TRIM29,LRIF1,RORB,TRAF1,CD274,LHFPL4,SYNGR1,MCPH1,ZNF655 |
| 4.649e-03 | -5.37 | NAXE (NAD(P)HX epimerase) | protein interactions | 128240 | 58 | 26 | 19454 | 5460 |
RPA3,BAP1,HSPA8,PYGB,HSPA5,ABHD10,PCK2,CCS,EHD1,H2AX,RPA2,CTSA,PCLAF,PLD3,PIH1D1,CCNF,SNX17,TENT5C,PRNP,SUCLG2,PMPCA,GMPS,MFN1,GSTO1,ZFAND6,ARMT1 |
| 4.649e-03 | -5.37 | ARHGEF4 (Rho guanine nucleotide exchange factor 4) | protein interactions | 50649 | 58 | 26 | 19454 | 5460 |
TP53,ZC3H14,TOP3B,CDC42,RBM22,BPGM,FLOT1,MBD3,CCDC86,YWHAZ,SERPINH1,YWHAB,DPY30,MOV10,RPS29,MLF2,PPIB,YWHAH,PPIL4,YWHAG,HNRNPL,SLAIN2,TMCC1,NUP35,CHCHD3,FUBP3 |
| 4.649e-03 | -5.37 | FBXW4 (F-box and WD repeat domain containing 4) | protein interactions | 6468 | 58 | 26 | 19454 | 5460 |
SLC25A11,CCT8,DDX5,DHX9,RUVBL1,PSMA2,RIGI,SKP1,COPS4,PFDN1,PDRG1,CCT5,PPP2R1A,PDCL,COPS2,TCP1,COPS7B,CCT7,ATP5PD,PFDN5,COPS7A,MCM4,COPS5,YWHAH,CCT2,PFDN2 |
| 4.649e-03 | -5.37 | MFSD8 (major facilitator superfamily domain containing 8) | protein interactions | 256471 | 58 | 26 | 19454 | 5460 |
FAM241A,CCR6,LAMP3,GPR17,KDSR,RAB2A,LAMP2,DNAJC19,ENDOD1,LAMTOR1,OPRL1,YIPF3,CYB5R1,TPRA1,CAV2,EPHX1,P2RY12,RAB9A,BSCL2,TSPAN15,CXCR4,TACR3,LPAR1,TNFSF8,SLC7A1,GABBR1 |
| 4.649e-03 | -5.37 | ENDOG (endonuclease G) | protein interactions | 2021 | 58 | 26 | 19454 | 5460 |
HTRA2,DNAJC7,COX14,SLC25A12,PARL,PLGRKT,DKC1,COX4I1,STUB1,AIFM1,TNKS,KCTD12,FEN1,TOP3B,APOO,PHB2,SLC25A51,FBXW7,SLC31A1,TUSC2,SFXN1,PSME1,PCGF2,BAG2,HSPA8,BIRC2 |
| 4.649e-03 | -5.37 | GLA (galactosidase alpha) | protein interactions | 2717 | 58 | 26 | 19454 | 5460 |
FAM20C,CUL3,CNOT2,DPP4,NTRK3,RC3H2,SEC61B,CNOT6,LMBR1L,G6PD,EGLN3,MAT2B,EIF4H,MARCHF4,ZNF622,TMEM205,ALG11,CAPN1,CNDP2,MET,RPA2,IGF1R,TERT,TMEM106B,RPA3,G3BP2 |
| 4.649e-03 | -5.37 | CSRP2 (cysteine and glycine rich protein 2) | protein interactions | 1466 | 58 | 26 | 19454 | 5460 |
TES,TRIM27,SMU1,CCNF,VIRMA,DDRGK1,CUL3,MYC,UBE2H,VMP1,COP1,TRIM23,ESYT1,EWSR1,RPA3,BAP1,MDC1,PIAS1,FBXW7,TOLLIP,STAU1,UFL1,EEF1A1,E2F4,KBTBD4,PIH1D1 |
| 4.671e-03 | -5.37 | positive regulation of B cell proliferation | biological process | GO:0030890 | 45 | 22 | 18204 | 5365 |
IL21,IL2,MEF2C,IL7,PELI1,CD81,CHRNB2,IL13,TLR4,TFRC,SASH3,IL5,TLR9,CD38,MIF,TICAM1,SLC39A10,BCL6,CD40,TIRAP,CDKN1A,IL4 |
| 4.695e-03 | -5.36 | FPGS (folylpolyglutamate synthase) | protein interactions | 2356 | 31 | 16 | 19454 | 5460 |
EGLN3,KRAS,HSCB,FBXW7,FAHD1,PALM2AKAP2,AMACR,RIT1,ACACA,QRSL1,ATG3,ACAA2,BICD2,LAMP2,TOR1AIP2,GPR17 |
| 4.695e-03 | -5.36 | BIRC8 (baculoviral IAP repeat containing 8) | protein interactions | 112401 | 31 | 16 | 19454 | 5460 |
UBE2W,DHX38,TNPO2,UBE2V1,RIOK2,PPFIBP1,UBE2D1,HTRA2,TMOD1,FAM107A,UBE2N,UBE2G2,BIRC2,UBE2K,DHX16,UBE2D3 |
| 4.695e-03 | -5.36 | CDC37L1 (cell division cycle 37 like 1, HSP90 cochaperone) | protein interactions | 55664 | 31 | 16 | 19454 | 5460 |
CDC37L1,DDX39A,RPS17,XPO1,RPS7,CHORDC1,HSP90B1,FKBP4,UBAP1,PTTG1,HSP90AA1,STUB1,RPS10,TTC4,PPP5C,HSP90AB1 |
| 4.695e-03 | -5.36 | ATG4A (autophagy related 4A cysteine peptidase) | protein interactions | 115201 | 31 | 16 | 19454 | 5460 |
RAB13,LCN15,UBB,GABARAP,NUF2,TSR3,THOC1,GABARAPL1,ATG101,MAP1LC3B,GABARAPL2,WDR37,HSPB6,SERPINB1,RB1CC1,BCAS4 |
| 4.695e-03 | -5.36 | FKBPL (FKBP prolyl isomerase like) | protein interactions | 63943 | 31 | 16 | 19454 | 5460 |
CSNK1E,CDKN1A,XPO1,MAP3K12,CSNK1A1L,ANKRD49,CSNK1A1,HSP90AA1,AHSA1,FAM107A,TUBA1B,CTU1,RBCK1,MATR3,KRAS,HSP90AB1 |
| 4.695e-03 | -5.36 | GPR25 (G protein-coupled receptor 25) | protein interactions | 2848 | 31 | 16 | 19454 | 5460 |
GJB1,TMEM237,TMEM248,PNMA1,GGT7,MFSD5,STOM,VAPB,LMNA,SLC35E3,CNIH4,ATP6V0E1,TPRA1,RETN,FATE1,RHCG |
| 4.695e-03 | -5.36 | BORCS7 (BLOC-1 related complex subunit 7) | protein interactions | 119032 | 31 | 16 | 19454 | 5460 |
RAB9A,HSPA8,BLOC1S2,PIP4P1,LAMTOR3,VRK1,BORCS6,SNAPIN,INSYN1,LAMTOR2,KXD1,PRPF19,BORCS8,BORCS5,LAMTOR1,BCAS4 |
| 4.695e-03 | -5.36 | DHRS13 (dehydrogenase/reductase 13) | protein interactions | 147015 | 31 | 16 | 19454 | 5460 |
ST7,DNAJC25,OTULINL,SEC62,SYP,ATP1A3,CCT2,FAS,TMT1A,KCNA2,CCNF,SEC61B,HSPA8,HSD17B11,RANBP6,TNFSF8 |
| 4.695e-03 | -5.36 | KCNA3 (potassium voltage-gated channel subfamily A member 3) | protein interactions | 3738 | 31 | 16 | 19454 | 5460 |
CTTN,DLG4,DLG1,HCLS1,KCNA2,NTRK2,NF2,CAV1,FABP4,PTP4A3,GRB10,DDX39A,SHC3,TFRC,DOLK,BAX |
| 4.699e-03 | -5.36 | KIF11 (kinesin family member 11) | protein interactions | 3832 | 252 | 90 | 19454 | 5460 |
TNFAIP3,MLF1,UBE2H,MAPRE1,RC3H2,PTEN,SRPK2,VIRMA,SMURF1,DHRS13,LDHA,NDN,CDK7,NOL7,PRKCA,UBE2M,RPA2,CDK1,SQSTM1,RPA3,BAP1,HSPA5,FBXW7,DGCR8,SUV39H1,EMC4,MAP4,H2AC4,SNRNP70,CRBN,PRR3,RPL32,EFNA3,ZBTB2,CDC5L,ILVBL,NAA11,PNMA3,SPPL3,FZR1,TP53,TRIM6,FBP1,RPL23A,MEPCE,RNF20,TOLLIP,H3C1,BTF3,RNF40,CUL3,MYC,RIT1,BRCA1,YWHAZ,PSMD14,ANAPC2,RPL37A,LMBR1L,APEX1,ELK4,BORCS6,PAFAH1B1,ANXA7,PPARG,EP300,HSPA8,FBXL4,UFL1,DDRGK1,YWHAH,HSPB8,INSYN1,TRIM8,IFI16,MED4,GJA1,CETN2,SUMO2,SNRPD3,KIF3B,RPS23,DCAF8L2,BAG2,BCL9,TRIP4,IRAK4,RPL28,KRAS,TNF |
| 4.699e-03 | -5.36 | RRP8 (ribosomal RNA processing 8) | protein interactions | 23378 | 252 | 90 | 19454 | 5460 |
RPL15,TAF1D,RBM34,LLPH,ILF2,RPL3,NOC4L,RPL17,GRSF1,SUV39H1,SNRNP70,CENPL,RPL10A,NOL12,RPL32,SRP14,SURF6,DKC1,RPS14,FGF13,ZCCHC17,LMNA,RPA2,MACROH2A2,RPLP0,RPL26L1,SIRT7,RPA3,RPL4,WDR3,DGCR8,NPM3,BRIX1,UTP23,RPL7A,RPF2,MECP2,POP7,EIF2AK2,RBMX2,PRKRA,FGFBP1,RPL13A,RSL24D1,SRPK2,ZNF263,RAF1,H1-3,MAK16,RPL18,PPAN,RPL31,RPS24,PICK1,HMGN4,H1-6,SRSF4,RPL28,DDX50,IFI16,NT5C2,MAP3K14,FBXO32,SRSF1,RPL8,LYAR,BET1,H1-5,SYK,USP39,APOBEC3C,IMPACT,ATP5IF1,NOP53,STAU1,FXR2,RAB11A,MYC,ZNF668,LMNB1,FTSJ3,H1-1,ILK,FAU,RPS9,RPL37A,RPF1,FBXO22,RPL19,ESR2 |
| 4.699e-03 | -5.36 | CBX1 (chromobox 1) | protein interactions | 10951 | 252 | 90 | 19454 | 5460 |
EZH2,RBPJ,MAX,E2F4,PPP2R1A,G3BP1,VDAC1,GTF3C3,PCGF6,SLC25A5,TOP2B,PCNA,KDM2A,HSPB1,IFI16,HMGA1,NDUFV2,AGK,CCDC71,HP1BP3,MAP2K1,ADNP,GTF2IRD1,NDUFA5,ACTL6A,STAU1,YAF2,EP300,BRCA1,MYC,DSN1,CUL3,RBBP4,DYNLL1,CBX5,LRIF1,MAD2L2,ZMYM2,CHAMP1,CBX3,ZFP1,RAD23B,NUPR1,ZNF581,LBR,ZMYM4,SPRR1B,ZMYM3,H3C1,HNRNPK,THRAP3,KPNA2,RING1,H2AC4,MAP4,BRD3,CSNK2A1,NR2F6,SUV39H1,ZBTB2,H2AZ1,RPL12,RB1,H2BC11,HNRNPH3,E2F6,RPL26L1,SUMO1,GTF3C4,H2AB1,KDM1A,NUCKS1,H2AC13,SS18,BAP1,BANF1,MIS12,MECP2,MAPRE1,BAHD1,NDUFB10,EXOC5,ST13,KPNA6,AR,ZNF518B,PSMC5,SNX12,MACROH2A1,TRIM24 |
| 4.699e-03 | -5.36 | BIRC6 (baculoviral IAP repeat containing 6) | protein interactions | 57448 | 252 | 90 | 19454 | 5460 |
CCDC22,SDF2L1,PNPO,STK11,PSMB2,TUFM,GRPEL2,MGST3,VIRMA,FERMT2,OPTN,CCNF,PTEN,PSMC5,STX17,LSM2,MRPS34,RPA2,HECTD1,DYRK2,CCL18,CAPN1,AKR7A2,CCNA2,USP8,KDM1A,GABARAP,MBD3,PIP4P1,LDOC1,SIRT7,RPA3,CSNK2A1,CCL17,ARL10,SPSB3,TP53,SNAP29,MAP1LC3B,MECR,TOR2A,ANAPC11,MSH6,HSD17B10,CLPB,HAPSTR1,RIT1,HTRA2,CUL3,RAB11A,MYC,AUH,CCNQ,CXCL1,SSH3,CD79B,MCPH1,ANAPC2,PHF21A,ISOC1,VAV2,PIH1D1,TIMM29,TMEM266,PHB2,HSCB,RNF41,CXCL3,EP300,AKAP1,DCTN3,BIRC2,UBE2D1,PEX3,CST3,NDC80,INSYN1,CACYBP,EGLN3,KRT8,MAP1LC3A,EZH2,VPS33A,POLR2C,TOP3B,TULP3,DIPK1A,RBBP7,IMMP2L,FBXO3 |
| 4.723e-03 | -5.36 | human chr2p23.3 | chromosome location | human chr2p23.3 | 75 | 27 | 26134 | 5823 |
SELENOI,TP53I3,OST4,FKBP1B,MPV17,UCN,PREB,EMILIN1,ADCY3,SF3B6,HADHA,KIF3C,TCF23,ZNF513,IFT172,PRR30,SLC5A6,ATRAID,TRIM54,PTRHD1,WDCP,CIMIP2C,SNX17,DNAJC27,PPM1G,SLC35F6,SUPT7L |
| 4.730e-03 | -5.35 | KCTD13 (potassium channel tetramerization domain containing 13) | protein interactions | 253980 | 47 | 22 | 19454 | 5460 |
VTA1,CEP97,PSMA1,ADRB2,KCTD10,TWNK,PCNA,NDST3,TNFAIP1,FAF1,NUDT18,POLD2,LSM3,PFDN2,ARMC7,PPARG,NTAQ1,HSPB8,TUBA1A,GORASP2,ZMYND19,CUL3 |
| 4.730e-03 | -5.35 | DSCC1 (DNA replication and sister chromatid cohesion 1) | protein interactions | 79075 | 47 | 22 | 19454 | 5460 |
SLC35G2,SLC39A7,P4HA2,PCNA,GTF2F1,CDIPT,RFC4,LGI1,EEF1AKMT3,NAA11,SSRP1,RFC3,RFC2,THOC1,RFC5,RFXANK,UBXN6,GSTM3,NAPA,VCPIP1,FAM81A,F9 |
| 4.730e-03 | -5.35 | ELP6 (elongator acetyltransferase complex subunit 6) | protein interactions | 54859 | 47 | 22 | 19454 | 5460 |
PSMA4,CIAO1,PSMC5,PHF21A,PSMA6,PSMB5,PSMB6,SRPK2,ZBTB2,ELP3,TOP3B,PSMC4,PSMB3,POLR2C,VPS33A,CLK1,PSMA3,KLHL15,ZBTB25,PSMA2,KDM1A,KRAS |
| 4.730e-03 | -5.35 | SH3BGRL3 (SH3 domain binding glutamate rich protein like 3) | protein interactions | 83442 | 47 | 22 | 19454 | 5460 |
CCNF,PEBP1,TES,RAB27A,PRNP,OXCT1,ESR2,RIGI,AHCYL1,GRPEL1,SUCLG2,USP3,DDIT4L,RAF1,LYPLA1,LYPLAL1,STXBP1,CDC42,AK2,NUPR1,SMARCB1,TST |
| 4.730e-03 | -5.35 | MAFF (MAF bZIP transcription factor F) | protein interactions | 23764 | 47 | 22 | 19454 | 5460 |
FOS,ATF3,NEK9,DDIT3,HDAC5,MIS12,BACH1,NFIL3,NFE2,APEX1,OVOL1,RTL6,TOP3B,MYC,NFE2L1,MAFG,DDX39A,NFE2L2,PPARG,ACACA,HOXD12,GIT2 |
| 4.737e-03 | -5.35 | transferase activity | molecular function | GO:0016740 | 2265 | 731 | 18094 | 5411 |
CASK,AGPAT5,CDK20,RNASEL,UBE2A,TESK1,CSNK1A1,GSTO2,CSGALNACT1,TNKS,HPGDS,TAMM41,CHST2,IGF1R,PHYKPL,CDK6,PRMT2,MMACHC,UMPS,FBXO25,POLR2F,MARCHF5,SIAH1,WWP2,PIK3CG,HADH,CCND1,RNF26,BUD23,FUT1,PAK6,UBE2E2,SRM,HAS3,METTL18,GYS1,TRIM52,RNF182,COQ8B,UBA3,NAA60,EEF1AKMT3,PELI1,DLST,CD38,ATAT1,RNF14,MGMT,TRMT13,FPGT,NAA11,CDKN1A,GSTA1,RIOK2,SHPRH,LANCL1,MAP2K1,SGMS2,DPH5,TRIM8,CDC42,MED31,TPST1,PIGW,TRMT61A,CHST11,NRP1,GALNT2,EXT1,FKTN,PRKCA,B4GALT6,TRMT1L,RNF152,HS2ST1,CDC23,XXYLT1,ADK,NTRK2,EPHA2,PGM2L1,TENT4A,FDFT1,EP300,BCKDK,IKBKB,UBE2W,ZDHHC14,GSTM4,UGT1A1,MYLIP,BAZ1B,PCMTD1,MGAT1,LACC1,POLR1B,NAA50,HEXA,VRK1,PRKAB1,ST3GAL5,B3GALT1,CERS6,DYRK1A,MAP3K21,B4GALT3,RLIM,CDK8,METTL6,SMURF1,PRDX6,ROCK2,CHPF,NEURL2,TENT2,MAT2A,NMRK1,UBE2L3,TRIM68,MAP2K3,PRKCQ,JAK2,OSGEPL1,ZDHHC4,FBXO9,MMD,SETD4,GGT7,SAT1,TSSK1B,TRMO,TST,DYRK2,CHST7,EPHA4,TENT5C,TLCD3B,ELOVL6,UCK1,SPHK2,SULT1B1,ABHD5,UBE2E3,ADCK1,DTL,B4GALT7,PML,METTL21A,FGFR1,PTK7,GTDC1,TRIM62,ARMT1,FAM20C,HNMT,PGK1,GLYAT,UBE2G2,UPRT,DAPK1,AK5,GALNT1,STK4,FBXO3,PPP1R11,ASB1,PARP2,DTYMK,SAT2,PPM1D,PRPF19,ALOX5AP,EZH2,ZDHHC17,OAS1,GK5,NME2,RPS6KA4,PIM2,PAFAH1B2,LRAT,VPS18,COX10,TRIM26,STK24,ELOVL1,CMAS,TRIM36,RNF115,NEK9,RAG1,TRIM5,MAPKAPK5,ANAPC11,WDSUB1,EXTL2,GALNT12,DNTT,DAPK3,E4F1,MED11,WSB1,RNF139,ROCK1,MGAT4A,TAF9,MAP3K14,PTAR1,ZNF451,ELOVL4,UCKL1,TRAF7,TERT,INMT,FBXO22,MDM2,AGPAT1,HS3ST1,AK3,PELI3,PCGF3,PLAAT5,POLE4,TRIM24,RNF181,ACVR1,CSGALNACT2,TRIM32,TRIM45,CHST10,FBXO30,PGAP4,TRIM27,CDK4,NTRK3,ALG11,THG1L,KMT5B,UBE2D1,CCL8,SYK,TRIM44,B4GALT4,GLUL,CCL2,MARCHF9,BFAR,CDK9,MAPK4,PLA2G15,PAK5,MUL1,POLR2B,SNRK,POLB,HS3ST5,TRIM6,TRAF6,GNMT,FGR,GPAM,TGFBR2,CHPF2,ETNK2,C1GALT1C1,JAK1,GLYATL3,MED21,MAEA,TRAF2,PCMTD2,METTL22,COMTD1,GPT,NT5C2,PAK2,HADHA,CISD1,MGST3,RNF208,HMBS,RNF167,DHPS,GAL3ST1,TRMT11,AASDHPPT,PRKD3,RNF11,TRIM35,PCYT1B,DOLK,CBLL1,CHKB,PRKACB,TYMS,FNTB,SELENOO,RNF146,IP6K1,SETD3,TNFAIP3,ACAT1,PGS1,FAM98A,POLR2L,AREL1,PNP,TRIM21,NDST1,HMGCS1,GSTT2B,ZDHHC8,UBL4A,PIGY,MEAF6,TNKS2,GSTT1,SIRT7,ST6GALNAC3,TRAF3IP2,G2E3,HS3ST3A1,RNF148,AGK,TRIM10,OAT,ANAPC4,SMARCE1,RBCK1,NT5C3A,GNPNAT1,PGGT1B,GAMT,PAPSS2,RNF7,EZH1,NTMT1,POLL,PAPOLB,HUWE1,PPAT,PARP11,DCAKD,POLR1D,QTRT2,UBE2I,NUDT5,PIK3R1,FTSJ3,LARGE1,RAF1,GSTP1,SBK2,SEPHS1,POLD4,TMT1B,CLIC2,BMPR2,ST3GAL4,CERS2,AANAT,CSNK1A1L,ATG3,RNF103,RNF144B,RNF128,GSTO1,AKT3,EMG1,CLK4,ZDHHC24,ACCS,ELOVL7,ACVR1B,PAFAH1B3,LIPT2,TNNI3K,KCTD10,MRM2,ST8SIA5,ILK,PTGES3,FBXL3,TRMT10B,CPT1B,TRMT5,PIK3CA,MET,PYGM,POLR3F,MGST2,RNF126,TRIM3,CREBBP,SETD5,CUL2,MAPK10,ACVR1C,METTL14,GSTM3,B3GNT2,LCMT1,SULT1A3,GAL3ST4,KCTD11,DPAGT1,FBXO11,ILVBL,IRF2BP1,IRF2BPL,B3GALT2,PRPSAP1,FN3KRP,PNPLA4,ST8SIA4,GNPTG,POLR2I,HERC3,TRMT112,ATG16L1,GBE1,GGPS1,DSTYK,GID4,ZNRF1,MAP3K12,DLAT,NPR2,TRIM37,STK11,MGAT5B,TBK1,GMPPA,SRC,FKRP,METTL25B,RNF20,CSNK1E,RNF141,QPCTL,GDPGP1,TNIK,CHRAC1,GXYLT2,ELOVL3,UBE2H,ELP3,TRIM63,PIP5K1A,GPHN,ETFBKMT,NME1,CMTR1,UBE2D3,ST3GAL2,NOSIP,NAT2,ITK,MPST,CSKMT,TERC,DMPK,CSNK1G3,IRAK4,PAPOLA,MAP3K3,NAA30,CERK,CDK5,PDSS2,GUK1,SETD7,MARCHF4,KARS1,FUT8,RMND5B,HENMT1,NIM1K,NUS1,PTDSS1,MTAP,DDR1,TRIM22,STK38,CDK12,PRKX,STRADB,PLAAT3,ABHD4,CDKL2,SIAH2,WWP1,IFNB1,RNF122,CMTR2,UBE2M,MGAT4B,PFKFB2,UCK2,UAP1,ZDHHC15,CDK7,METTL15,B3GALT4,STK38L,UBR7,UBE2N,GALNT4,TNFAIP1,TRIM15,RNF133,UBIAD1,TRIM11,CKB,RNF8,UGT2A3,COP1,SEPHS2,TESK2,TFB1M,UBE2K,TRIB1,GNPAT,FBXO7,CCL5,MARCHF3,STYK1,OXCT1,HEXB,AK2,UHMK1,GFPT1,TKTL1,SPTSSB,PIK3R3,ARF4,NAT9,CBL,EIF2AK2,CDK1,PRDM4,PHKG1,NEK2,SRPK2,KLHL9,ALG2,UFL1,EEF2KMT,CRAT,RC3H2,GSTM5,SHMT1,POLR3B,TMT1A,GALNT17,CHST1,UGP2,UBE2F,TOP1,WEE2,RNF121,AMT,PHKA1,MED17,POLR1H,PIAS1,B4GAT1,CTU1,RNF5,MB21D2,PYGB,SCYL2,FBXL14,FTSJ1,HSPB8,CPT2,CAMK2G,PSKH1,ACAA2,RPN1,CLP1,ANKIB1,CDC7,PRKAG1,PIP4K2C,TAFAZZIN,PRMT6,STUB1,PRPS1,HECW1,SGMS1,CSNK2A1,TENT5D,YKT6,RNF39,GLT8D1,TRIM34,EPHB6,CGAS,CHST9,ART5,HECTD1,BMPR1B,OXSR1,DBT,TYW3,DLG1,SUV39H1,PIGA,LPCAT3,CMPK1,CSK,POLR3H,GAPDH,GSK3A,ABHD14B,RING1,STK3,TRIM23,HECTD3,STK16,TSR3,AKT1,EFNA3,RABGGTB,STT3A,MED27,MCAT,LNX2,ZBED1,EED,SOSTDC1,PRKCE,NAA15,NDST3,CSNK2B,ST3GAL1,RNF187,SETD9,METTL24,CCAR1,BIRC2,DTWD1,VCPKMT,PRMT5,COQ8A,DKC1,STK26,BRCA1,SMYD3,POLE3,RNF10,BMPR1A,CCND3,FBXO44,RNF41,MAB21L1,POMT2,GMPPB,TRIM54,MEPCE,GK2,PTGES,MAP3K11,TAF10,GSTA4,RCHY1,FUT9,KIT,RNF34,MED10,MPP1,CDK17,EGR2,BRAP,POLR2C,AKT2,HERC4,ZDHHC16,CLK1,YES1,NAA16,METTL2A,LIAS,B4GALT1,SYVN1,ALG5,MED30,GSTK1,CAMK1,DYRK1B,UST,COMT,JADE1,CCL3,DTWD2,MAP2K6,MAPKAPK3,NME4,GSTA2,SELENOI,NEK7,UBE2B,ST6GAL1,GTF2B,DCK,UBE2S,GLT8D2,CUL3,CAMKV,MSL2,RNF40,FHIT,ASMT,TOPORS,OSGEP,SPTSSA,GCNT3,B3GALNT1,CHST13,WSCD1,CDK5R1,GXYLT1,GTF3C4,UGCG,RNF113A,CDIPT,GSTM2,FAM20B,PRKCB,UBE3A |
| 4.737e-03 | -5.35 | regulation of macroautophagy | biological process | GO:0016241 | 178 | 69 | 18204 | 5365 |
EXOC1,BAG3,SESN2,RHEB,IL4,TSPO,ATP6V1E2,CSNK2A1,HSPB8,TBK1,CAPN1,FEZ1,MTM1,BECN1,PIP4K2C,SCFD1,EXOC8,GAPDH,SH3GLB1,TMEM39A,SUPT5H,FBXO7,ATP6V1A,PHF23,BNIP3L,CTTN,SLC25A5,LYPLA1,PARL,OPTN,PIM2,GSK3A,AKT1,ATP6V1G1,RALB,VDAC1,CDK5,ATP6V1C1,VPS26B,STUB1,CDK5R1,C9orf72,WDR45,ADRB2,RNF41,FBXW7,POLDIP2,PAFAH1B2,ATP6V1D,VPS26A,HDAC6,ATP6V0E1,GNAI3,SNX18,TP53,TBC1D25,ATP6V1G2,FKBP8,SNX5,PIK3CA,ATP6V0B,USP30,NUPR1,LACRT,TOM1,TRIM32,SESN3,SLC25A4,SEC22B |
| 4.750e-03 | -5.35 | YEATS4 (YEATS domain containing 4) | protein interactions | 8089 | 174 | 65 | 19454 | 5460 |
GOLGA5,AGGF1,MED23,JUP,GIT2,PLAC1,ING5,ACTL6A,OIP5,KDM1A,UPF3B,FOS,PPM1G,GRAMD2B,ATG3,CSGALNACT1,UBE2H,CCHCR1,PTTG1,MORF4L1,ZNF687,SUGP1,MYC,COX6B1,ACTB,GABPA,REEP3,TRIM54,ESR2,VPS72,S100A6,GTF2F2,PHF21A,GTF2F1,TRIM24,H2BC1,DMAP1,RNF8,SMARCB1,MAX,ZNHIT1,ANP32A,ELF1,MLLT6,RUVBL1,H3C1,POLDIP3,PFDN1,TFPT,RUVBL2,FOSL2,BRD3,FBXO34,POU5F1,ACTL6B,FIG4,CSNK2A1,XPO1,CCAR2,MEAF6,HMG20A,NUF2,POLE3,H2AZ1,RPRD1A |
| 4.750e-03 | -5.35 | EXOSC2 (exosome component 2) | protein interactions | 23404 | 174 | 65 | 19454 | 5460 |
PALS2,PIH1D1,UTP15,STK38,STAU1,UFL1,G3BP2,METTL22,FBXL4,UPF3B,DDX46,LUM,BAP1,SNAPC1,EMG1,C1D,MTDH,EXOSC4,ATG3,RC3H2,BICD2,PSKH1,RBM7,RIT1,EXOSC1,DHPS,MYC,RPL35,GPX1,DEK,ESR2,PRRC2A,ROMO1,RAN,RSRC1,PELO,PSPC1,PTEN,EXOSC3,MOB3C,RNF8,EXOSC8,MAP1LC3B,KRAS,H3C1,PSMA2,MDC1,MEPCE,RINT1,OSTM1,SNRNP70,ZCCHC9,MPHOSPH6,DRG1,CDK12,IFI16,DDRGK1,DIS3L,ATG7,FZR1,CAND1,RPS16,MALSU1,EIF4E2,PHB1 |
| 4.750e-03 | -5.35 | NCKAP1 (NCK associated protein 1) | protein interactions | 10787 | 174 | 65 | 19454 | 5460 |
YWHAB,SPP1,NCK1,MPPED2,YWHAH,HDAC6,ATG7,COPS5,YWHAG,WWP2,ZNF511,CCAR2,NYAP2,RAC2,H2AZ1,HOMER3,FBXO32,STK16,PSMC3,EZH2,MECR,ARHGAP12,ARFGEF1,EPHA4,HUWE1,KRAS,TOLLIP,ROCK2,GARRE1,PDCD4,UBE2H,BICD2,YWHAZ,H1-10,MCM4,FGFR1OP2,CAP2,MYC,HOMER1,VIRMA,ESR2,FBXO22,ACTB,PSMD6,CCNF,LMBR1L,ACACA,PIH1D1,CSNK1G3,RPA2,METTL14,FGFR1,ETF1,POLA2,WASF3,HSPA5,CYFIP2,SGF29,STAU1,STK38,HSPA8,STK26,RPA3,BAP1,SIRT7 |
| 4.767e-03 | -5.35 | Regulation of nuclear SMAD2/3 signaling | Pathway Interaction DB | smad2_3nuclearpathway | 76 | 38 | 2226 | 782 |
CDK4,JUN,ZBTB17,CREBBP,IRF7,IFNB1,CTBP1,TGIF2,CBFB,EP300,HSPA8,CREB1,SMAD2,SMAD4,VDR,IL5,CDKN1A,ITGB5,MAX,SAP18,AKT1,ATF3,DLX1,TFE3,SAP30,RBBP4,IL10,AR,CITED1,COL1A2,MEF2C,FOS,SNIP1,SIN3A,RBBP7,SP1,MYC,SMAD3 |
| 4.769e-03 | -5.35 | NDUFB4 (NADH:ubiquinone oxidoreductase subunit B4) | protein interactions | 4710 | 78 | 33 | 19454 | 5460 |
FTL,TOMM20,DNAJC30,VDAC1,HSCB,SDHC,NDUFA4,SNIP1,MME,RPA3,CSNK1A1,NDUFA12,NDUFS6,NDUFS3,LMNA,DDX39A,TIMMDC1,MPV17,NUP35,ESR2,EGLN3,MYL12A,KCTD10,RPGRIP1L,LAMTOR3,NDUFA1,FUT1,PHB1,NRP1,BAG3,NDUFV2,GTF2E1,MYC |
| 4.769e-03 | -5.35 | BPLF1 (large tegument protein) | protein interactions | 3783726 | 78 | 33 | 19454 | 5460 |
YWHAH,XPO1,YWHAG,MCM4,KARS1,MOV10,SMARCA5,CUL3,STOML2,CUL2,AP2A1,YWHAB,TRAF6,PSMD14,YWHAZ,PSMC5,SEC63,NUP153,PSMC4,RPS11,UBE2M,PSMC3,HGS,RUVBL2,PCNA,SQSTM1,UBE2A,MARS1,SSRP1,NEDD8,HUWE1,NUP107,CSE1L |
| 4.769e-03 | -5.35 | MYG1 (MYG1 exonuclease) | protein interactions | 60314 | 78 | 33 | 19454 | 5460 |
AGR2,SYP,DESI2,SORD,HSPB1,HSP90AA1,AHSA1,COPS5,SUMO2,NDN,HSP90AB1,TLCD4,CCNF,TMEM229B,DSTN,SYNGR1,CTSA,CPLX2,AGTRAP,DPH5,DDIT4L,SPG21,DDX39A,OXCT1,XPNPEP1,RBBP7,RIGI,DDX39B,HSPD1,RPA3,IDH1,YIF1A,HSPA8 |
| 4.769e-03 | -5.35 | CLASRP (CLK4 associating serine/arginine rich protein) | protein interactions | 11129 | 78 | 33 | 19454 | 5460 |
RPS27A,COIL,RTKN,RPA3,SNIP1,CLK1,EZH2,RPA2,TMEM184B,DYRK2,JPH4,UBL3,ATG16L1,VDR,RBM38,SNRNP40,SNX3,RBBP4,DYRK1A,ESR2,SRPK2,ATXN1L,SMAD3,CLK4,CDK6,EED,SNRNP70,DDX23,RIT1,UBE2H,COP1,CFAP20,XPO1 |
| 4.769e-03 | -5.35 | PHC3 (polyhomeotic homolog 3) | protein interactions | 80012 | 78 | 33 | 19454 | 5460 |
FBLN5,RPS3,KRT8,ALB,EED,SNRNP40,HYPK,VIRMA,ESR2,AGR2,LMNB1,TMEM106B,MCRIP2,RPA3,YAF2,BAG2,PCGF2,RING1,SCML1,CBX7,PCGF3,SKP1,RIGI,PCGF6,DDI1,TP53,RAF1,SAP30,SOX2,SFTPC,PHC1,NUFIP2,E2F6 |
| 4.769e-03 | -5.35 | response to reactive oxygen species | biological process | GO:0000302 | 181 | 70 | 18204 | 5365 |
FXN,BECN1,MIRLET7B,CAPN2,HBB,SOD1,TXNRD2,PPIF,NQO1,TACR1,CYP1B1,FKBP1B,HP,MAP1LC3A,CCS,EZH2,OGG1,CRYGD,FOS,NFE2L2,STAT1,TXNIP,KLF4,HDAC6,STAT6,GPR37L1,RHOB,OSER1,PPP2CB,PRDX1,TOP2B,JUN,PRDX2,PCGF2,SRC,AIFM1,MPV17,AKT1,HSPA8,GLRX2,SOD3,PEX13,CDK1,HBA1,TNFAIP3,CYGB,HYAL2,GSTP1,RLIG1,PCNA,BAK1,TXN,IL6,MIR34A,MT3,MMP9,MIR107,SOD2,RPS3,IL18BP,GPX1,PRDX3,CRYAB,ROMO1,UCP2,GPR37,MDM2,PDCD10,IL1A,UBE3A |
| 4.773e-03 | -5.34 | Translesion synthesis by POLK | REACTOME pathways | R-HSA-5655862 | 17 | 11 | 10285 | 3229 |
RFC3,RFC4,UBB,RPA2,MAD2L2,RPS27A,UBA52,RFC5,RPA3,RFC2,PCNA |
| 4.773e-03 | -5.34 | Translesion synthesis by POLI | REACTOME pathways | R-HSA-5656121 | 17 | 11 | 10285 | 3229 |
MAD2L2,RPS27A,UBA52,RFC4,RFC3,UBB,RPA2,RPA3,PCNA,RFC2,RFC5 |
| 4.777e-03 | -5.34 | steroid biosynthetic process | biological process | GO:0006694 | 114 | 47 | 18204 | 5365 |
CYP2R1,ACAA2,STAR,CYP39A1,HSD17B11,CYP11B2,CYB5R3,LHB,CYP27A1,CYP17A1,OSBP,HSD17B10,NPC1L1,AKR1B1,HSD17B6,HSD17B8,LBR,INSIG2,CH25H,MSMO1,AMACR,SDR42E1,ERRFI1,CYB5R1,HMGCS1,HSD17B3,CYP11B1,FDFT1,DHRS11,ERG28,CYP27B1,HINT2,LIPA,NSDHL,CYP7A1,SRD5A3,PLPP6,CYP1A1,CYP21A2,ACOT8,SC5D,MVD,HSD17B1,TSPO,CFTR,G6PD,FAXDC2 |
| 4.788e-03 | -5.34 | DNAJA2 (DnaJ heat shock protein family (Hsp40) member A2) | protein interactions | 10294 | 520 | 173 | 19454 | 5460 |
CDC40,NEDD8,PSMA5,FKBP8,MEPCE,MAP1B,NUPR1,TP53,MTCH2,KCTD3,FZR1,H2AC4,SNRNP70,SHC1,USP15,COPS5,SLC25A51,HSPA5,BAP1,RNF113A,DERL1,CWF19L1,SAMM50,FGFR1,WRAP53,DNAJC24,TRIM36,CFTR,GABRA1,CDC20,FAM210A,PSMA6,TRAF7,RC3H2,GEMIN8,UBE2H,DTL,SLC25A1,SMARCA5,DNAJC5,RUVBL1,PSMA1,HDAC11,PDHA1,NUDT19,TUBB4B,GLE1,MOB3C,TOP3B,SOX2,TUBA1A,TCP1,DYNC1I2,FAM98A,PCSK9,HSP90AB1,ELK1,AGR2,POU5F1,WWP2,DDRGK1,XPO1,STAU1,UFL1,EMC1,DDX39B,HIRA,AKAP1,HSPA8,MAP2K1,ADSS2,FDFT1,SHMT1,BORCS6,KBTBD6,LMBR1L,ANAPC2,PRMT5,TRMT11,LAMTOR1,MYC,BAG3,BTF3,BACH1,HUWE1,PSEN1,SFXN1,GARRE1,EHD4,PPP1R12A,IGF1R,ACTR2,APEH,KLHL26,MLLT11,TBK1,MAP2K3,PRNP,ARF6,SLC25A12,RCHY1,EEF1AKMT3,SMAD3,AIFM1,RB1,DNAJC7,ERCC3,HDAC6,HMGB1,FBXW7,NF2,CRYZ,SQSTM1,GRM2,METTL14,CCND1,PIP5K1A,PSMC4,ATG16L1,ELP3,COPE,VIRMA,TUBA1B,CCNF,STUB1,SENP5,PTEN,WDR45,TXNIP,ASCC1,SMAD2,RHOBTB3,FBXO7,ETFA,RBBP7,WDR19,FLOT1,TRIP4,NEK9,BAG2,EZH2,OTULIN,POLR2C,DTWD2,RAF1,B3GNT2,OCRL,LRWD1,EGLN3,PHB1,IFIT2,WDR6,BRD9,GJA1,RPL23,HAX1,RADX,HSCB,DNAJC3,NOTCH2,MTX2,EHD1,RBBP4,CHCHD3,IFT172,DCAF4,BRCA1,BLVRA,NLRP3,ILK,HSP90AA1,NTRK3,CUL3 |
| 4.798e-03 | -5.34 | FGFR2 mutant receptor activation | REACTOME pathways | R-HSA-1839126 | 33 | 18 | 10285 | 3229 |
FGF16,FGF3,FGF7,NCBP2,POLR2B,FGF10,FGF17,FGF1,POLR2F,FGF23,GTF2F2,POLR2G,POLR2C,FGF22,POLR2I,POLR2L,POLR2D,GTF2F1 |
| 4.806e-03 | -5.34 | DAP12 interactions | REACTOME pathways | R-HSA-2172127 | 371 | 140 | 10285 | 3229 |
MAP2K1,KRAS,RAP1B,RAF1,TNRC6C,UBA52,FGF22,SYK,WDR83,SRC,DUSP9,PSMD10,FRS3,FGF10,PIK3AP1,MOV10,FGF23,PSMA5,PTEN,MET,PAQR3,PSMB3,PEBP1,PDE1A,SPTAN1,PPP2R5E,PIP5K1A,ICOS,IL2RG,PIK3R2,DUSP6,PPP2R5A,FGF1,MDM2,YWHAB,CD86,PSMA1,TP53,PSMC3,SPRED1,PHB1,PSMD4,IL3,RPS27A,PSMB4,RASGRP3,SHC1,DUSP1,KLRC2,SEM1,PIP4K2C,HRAS,GAB1,KIT,LAMTOR2,PPP2CB,IL5,AKT1,PSMA6,AKT3,PEA15,PIK3CA,PSMB2,PSMD1,IL2RB,CAMK2G,LAMTOR3,FGF16,PSMC1,CUL3,IER3,VWF,PTPN11,PSMD14,LCP2,UBB,PPP2R1A,PRKCA,PRKACB,ANGPT1,PSME1,PDE1B,SPTBN1,AGO1,PPP5C,PSMD7,CD80,FGF17,IL2,TYROBP,PSMC5,FGFR1,PSMB11,PSMB10,B2M,KLRD1,PSMA4,CD28,DLG4,BRAP,CSK,PSMB6,PSMA2,ADCY2,PIK3R1,PSMB1,AHCYL1,CREB1,PSMD3,JAK2,PSMB7,CDKN1B,PSMC4,PSMA3,PSMB5,VAV2,ADCY3,GRAP2,GSK3A,BAD,MAP3K11,NEFL,DUSP10,PSMD6,HBEGF,FGF3,PSME2,PSMB9,SPRED2,IL2RA,AKT2,RAP1A,SHC3,PIK3R3,PRKCE,CDKN1A,CSF2,PSMD12,FGF7,JAK1 |
| 4.806e-03 | -5.34 | biliary_tract-gallbladder-other-adenoma | COSMIC cancer mutations | biliary_tract-gallbladder-other-adenoma | 23 | 13 | 16828 | 4835 |
IDH1,HRAS,KRAS,MAP2K1,GNAQ,IDH2,AKT1,TP53,KIT,GNA11,CTNNB1,PTEN,PIK3CA |
| 4.806e-03 | -5.34 | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | COSMIC cancer mutations | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | 23 | 13 | 16828 | 4835 |
MAP2K1,GNAQ,IDH1,HRAS,KRAS,PTEN,PIK3CA,IDH2,AKT1,TP53,KIT,GNA11,CTNNB1 |
| 4.810e-03 | -5.34 | SEPTIN2 (septin 2) | protein interactions | 4735 | 171 | 64 | 19454 | 5460 |
XPO5,COPS2,CD274,SRSF10,PLEKHF2,CSNK2A1,XPO1,TRA2A,STX1A,AGR2,SEPTIN7,UBE3A,SRSF7,FLOT1,RIGI,VDAC1,HNRNPK,EEF1A1,SOX2,NCSTN,ISG15,UBR7,UBL5,IRGQ,TPBG,NUPR1,JPT2,MOB3C,EZH2,SURF4,CCNF,VDAC2,CTNNA1,VIRMA,ESR2,COPE,BUB3,AIPL1,HMGCS1,RNF40,SMARCA5,BRCA1,RHOB,EP300,SEPTIN6,DNAJC3,RPA3,BAP1,PML,SAP18,HSPA5,CDC42EP4,SNX24,TRA2B,STAU1,PIK3R2,CDC42,MRPL12,TANK,KLC2,RPA2,ARMCX3,ZNF326,ADNP |
| 4.842e-03 | -5.33 | DPPA2 (developmental pluripotency associated 2) | protein interactions | 151871 | 21 | 12 | 19454 | 5460 |
VTA1,FGF12,FXR2,DPPA2,SPOP,UBE2I,AP2M1,SETD5,ZCCHC10,ZNF250,DVL2,EIF1AD |
| 4.842e-03 | -5.33 | USP29 (ubiquitin specific peptidase 29) | protein interactions | 57663 | 21 | 12 | 19454 | 5460 |
NFE2L2,CTDSP1,CTNNB1,CTDSP2,TP53,MYC,VIRMA,CGAS,CCAR2,CTSB,MAVS,HRAS |
| 4.842e-03 | -5.33 | PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A) | protein interactions | 94274 | 21 | 12 | 19454 | 5460 |
PRNP,PRKCE,YWHAZ,DAPK1,CSNK1G3,CSNK1A1,PRKCA,WDR77,CSNK1E,MYC,PRMT5,DDX39A |
| 4.842e-03 | -5.33 | TSPAN12 (tetraspanin 12) | protein interactions | 23554 | 21 | 12 | 19454 | 5460 |
TMEM182,TFCP2,MGST3,RNF152,GPR37L1,TEX264,STX8,PMP22,CYBC1,TMEM147,EMP3,CTXN3 |
| 4.842e-03 | -5.33 | HTR2A (5-hydroxytryptamine receptor 2A) | protein interactions | 3356 | 21 | 12 | 19454 | 5460 |
NTRK3,CBL,GNAQ,NDUFB10,ARF6,PPP5C,JAK2,GNA11,ARF1,GLUL,DLG4,DLG1 |
| 4.842e-03 | -5.33 | HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1) | protein interactions | 3290 | 21 | 12 | 19454 | 5460 |
TMX2,CD36,NPTX1,ACSL4,GKAP1,DIPK1A,CDC42SE2,TMBIM6,TMX4,DAD1,RAB18,OS9 |
| 4.857e-03 | -5.33 | SNARE | interpro domains | IPR010989 | 18 | 11 | 18521 | 5414 |
STX16,STX5,VTI1B,GOSR2,STX11,STX7,STX12,STX10,STX17,STX1A,STX6 |
| 4.871e-03 | -5.32 | positive regulation of hemopoiesis | biological process | GO:1903708 | 193 | 74 | 18204 | 5365 |
IL2RA,LGALS3,IL5,IL15,TYROBP,HCLS1,FOS,IL34,SMARCB1,WNT10B,IL15RA,IL23A,RAG1,CD80,CBFB,CCR1,BAD,IL7,RB1,SMARCD3,XBP1,PRKCA,SOCS5,RUNX1,NLRP3,TRAF6,ZBTB16,IL4,CD46,IL2,TGFBR2,CCL19,EEIG1,CTNNBIP1,TRIB1,CD4,MIR21,LILRB4,RHOH,ACTL6B,ACTB,EP300,NOTCH2,VSIR,TNF,IFNG,MMP14,IL10,IL12B,TESPA1,CREB1,MIR145,CD86,TOX,IL2RG,HMGB1,ACTL6A,SASH3,NKAP,SYK,PPP3CA,CD83,IL18,PNP,FOXP3,BCL6,KLF10,BTN2A2,HAX1,TESC,SMARCE1,AGER,DUSP10,KLHL25 |
| 4.871e-03 | -5.32 | positive regulation of leukocyte differentiation | biological process | GO:1902107 | 193 | 74 | 18204 | 5365 |
TESC,HAX1,BTN2A2,KLHL25,DUSP10,AGER,SMARCE1,PNP,IL18,PPP3CA,CD83,SYK,HMGB1,SASH3,ACTL6A,NKAP,KLF10,BCL6,FOXP3,CREB1,MIR145,TESPA1,TOX,IL2RG,CD86,TNF,VSIR,NOTCH2,ACTL6B,ACTB,EP300,MMP14,IL12B,IL10,IFNG,CCL19,EEIG1,IL2,TGFBR2,CD46,RHOH,LILRB4,TRIB1,CTNNBIP1,CD4,MIR21,RUNX1,SOCS5,PRKCA,SMARCD3,XBP1,IL4,ZBTB16,NLRP3,TRAF6,CBFB,CD80,CCR1,RAG1,IL15RA,IL23A,RB1,IL7,BAD,TYROBP,HCLS1,FOS,IL15,LGALS3,IL5,IL2RA,WNT10B,SMARCB1,IL34 |
| 4.880e-03 | -5.32 | G_gamma | smart domains | SM01224 | 17 | 10 | 9717 | 2575 |
GNG10,GNG2,RGS6,GNG5,GNG7,GNG12,GNGT2,GNG13,GNG3,GNG11 |
| 4.880e-03 | -5.32 | TLC | smart domains | SM00724 | 17 | 10 | 9717 | 2575 |
CLN8,TLCD1,TRAM2,TRAM1,TLCD4,TLCD2,CERS6,TLCD3B,CERS2,TRAM1L1 |
| 4.880e-03 | -5.32 | GGL | smart domains | SM00224 | 17 | 10 | 9717 | 2575 |
GNG12,GNGT2,GNG7,GNG11,GNG13,GNG3,GNG10,RGS6,GNG5,GNG2 |
| 4.886e-03 | -5.32 | Telomere Extension By Telomerase | REACTOME pathways | R-HSA-171319 | 7 | 6 | 10285 | 3229 |
RUVBL2,TERT,RUVBL1,DKC1,NHP2,WRAP53 |
| 4.886e-03 | -5.32 | Phosphate bond hydrolysis by NUDT proteins | REACTOME pathways | R-HSA-2393930 | 7 | 6 | 10285 | 3229 |
NUDT18,ADPRM,NUDT5,NUDT1,NUDT16,NUDT9 |
| 4.892e-03 | -5.32 | SMG6 (SMG6 nonsense mediated mRNA decay factor) | protein interactions | 23293 | 81 | 34 | 19454 | 5460 |
RMDN3,CSNK2B,EIF4A3,SRSF1,PHB1,PRRC2A,DKC1,HNRNPL,MAGOHB,PPP1CC,ANAPC15,MAGOH,UCK1,AP2A1,RC3H2,TERT,SMG5,PABPC1,UPF3B,BRIX1,RIGI,NHP2,THRAP3,FBXW7,KRAS,PSENEN,AGO1,SOX2,YTHDF2,TOP3B,GTPBP1,METTL14,HBB,WRAP53 |
| 4.892e-03 | -5.32 | SLC30A7 (solute carrier family 30 member 7) | protein interactions | 148867 | 81 | 34 | 19454 | 5460 |
LAMP3,DNAJC5,LAMP2,ST3GAL1,CSK,UBE2H,SPOP,RIC3,EDNRA,GPR173,SPINT2,CCNF,HRAS,S1PR4,EGLN3,ESR2,LYPD6,OTULINL,YIPF5,CLEC2B,KLRD1,CRELD1,RPA2,P2RY12,GPR35,LPAR2,VIPR1,RPA3,CD40,TSPAN15,TMEM106B,UST,KRAS,LPAR1 |
| 4.892e-03 | -5.32 | PYCARD (PYD and CARD domain containing) | protein interactions | 29108 | 81 | 34 | 19454 | 5460 |
AGPAT1,NLRP3,PYDC2,IKBKB,BECN1,TRAF6,EXOC5,MCM4,RALB,IFI16,CUL2,USP3,PYCARD,ESR2,NLRP1,MAP1LC3A,LIG3,CCL21,CCR1,BIRC5,LEMD3,NLRP2,STX17,BMPR2,NLRP6,IL6ST,NEK7,FCF1,NAA15,SSBP2,PELI1,NUP107,SQSTM1,PML |
| 4.892e-03 | -5.32 | ZMYM6 (zinc finger MYM-type containing 6) | protein interactions | 9204 | 81 | 34 | 19454 | 5460 |
SPPL3,C1QTNF1,TAB1,ACTB,DYNLL1,CDK9,TRAF1,OPTN,VAMP3,PLEKHO2,TPGS2,TNFAIP6,EMILIN1,LMO2,NOL4,PCBD1,ISCA2,TUFM,UCHL3,CTNNBL1,ASF1A,LDOC1,PPWD1,HSPA5,LTBR,FHL3,TUBB4B,LMNA,PNMA2,ZNF263,PTS,CTDSP2,PRDX3,TMEM59 |
| 4.899e-03 | -5.32 | CIITA (class II major histocompatibility complex transactivator) | protein interactions | 4261 | 39 | 19 | 19454 | 5460 |
ACTB,RFX5,FBXO11,HDAC5,PSMC5,TRIM22,EP300,GTF2B,PML,TAF9,PSMC3,PPARG,CDK1,RFXANK,XPO1,CREBBP,IFI16,NFYB,CUL3 |
| 4.899e-03 | -5.32 | ANKRD27 (ankyrin repeat domain 27) | protein interactions | 84079 | 39 | 19 | 19454 | 5460 |
YWHAH,SMAD1,MYC,ATG9A,VPS26A,TP53,CUL3,TBC1D4,LAMTOR1,YWHAZ,RAB4A,VPS26B,RAB9A,SRSF1,EEF1AKMT3,NFKBIA,VAMP7,ESR2,RBBP4 |
| 4.899e-03 | -5.32 | SNRNP35 (small nuclear ribonucleoprotein U11/U12 subunit 35) | protein interactions | 11066 | 39 | 19 | 19454 | 5460 |
ZCRB1,SNRNP70,ILK,SNRPE,CKS1B,SNRPN,SNRPB,PLEKHF2,KRAS,SNRNP48,SNRPD3,TAB1,SRPK2,SNRPG,RIGI,SNRPD2,SF3B1,SNAPC3,ZMAT5 |
| 4.899e-03 | -5.32 | OSBPL5 (oxysterol binding protein like 5) | protein interactions | 114879 | 39 | 19 | 19454 | 5460 |
P2RY1,OSBPL8,HGS,CDC23,NRP1,IPO8,TOP3B,YWHAH,SEC62,SNAP25,LHFPL1,HNRNPL,ESR2,FTL,LRIF1,PDE2A,KLHL23,OR1M1,VIPR1 |
| 4.899e-03 | -5.32 | ZHX3 (zinc fingers and homeoboxes 3) | protein interactions | 23051 | 39 | 19 | 19454 | 5460 |
CSNK2B,ZHX1,TRIM21,EWSR1,PDIA6,ZHX3,VIRMA,ESR2,FBXO22,NTAQ1,KLF12,AR,CSK,MYC,NFYA,RPL7A,BRD3,KLF3,CBX3 |
| 4.899e-03 | -5.32 | HOXB1 (homeobox B1) | protein interactions | 3211 | 39 | 19 | 19454 | 5460 |
CREBBP,KLHL9,HOXB1,CDK7,TUBA1A,CCNH,EHD1,SERPINA3,AK2,HAX1,RCHY1,AIFM1,EP300,TRAF7,CLPB,GGT7,HMGB1,MNAT1,PAX6 |
| 4.899e-03 | -5.32 | BCAP29 (B cell receptor associated protein 29) | protein interactions | 55973 | 39 | 19 | 19454 | 5460 |
VDAC1,HNRNPL,COPE,ARHGAP15,LMAN1,TMT1A,PHB1,COX4I1,RPA3,SEC61B,SSR1,ATP5PO,RPN1,RPA2,SERPINA5,PGRMC1,SCN3B,RAB2A,CREB3 |
| 4.900e-03 | -5.32 | DAPK1 (death associated protein kinase 1) | protein interactions | 1612 | 199 | 73 | 19454 | 5460 |
RCHY1,HRAS,DSTN,CORO1C,ADD1,SPTAN1,SLAIN2,SRSF10,MDM2,CNTROB,RASGRP2,PPP2R5A,LAMP2,TPM3,AGR2,BECN1,TMOD2,YWHAB,STX1A,BAG2,RPAP3,MYO1B,TOM1,PELI1,ADD2,PAK6,CAPZA1,CDC42SE1,TP53,EEF2,GASK1B,ACTN4,PPP2R1A,ACTR2,KRIT1,NECAP1,ARPC3,CAPZA2,TUBB4B,VGLL4,APEX2,CTTN,FBXL14,PAPSS2,CDC42EP3,STUB1,GTF2F1,TMOD3,DAPK1,DTWD1,CUL3,CNTNAP1,RAB11A,HYCC2,ST13,CFL2,H2BC9,RFC5,IVNS1ABP,MYO6,FBXW11,HSP90AA1,NCKIPSD,PIM2,FAM107A,SNRPA,ARPC2,DDX5,MYL12B,SPTBN1,GTF3C4,TPD52L1,TMOD1 |
| 4.907e-03 | -5.32 | SPRED2 (sprouty related EVH1 domain containing 2) | protein interactions | 200734 | 61 | 27 | 19454 | 5460 |
ATG7,ACTL6B,MDFI,CTSD,ZNF250,NDUFB7,TESK1,TSNAX,ZNF575,RHOB,SMCHD1,MAP1LC3A,DYRK1A,CPT2,SPG21,ARFGAP1,TOP3B,FAM162A,GNAQ,STOM,GNG5,MTDH,SQSTM1,ZDHHC17,RIGI,KIT,KRAS |
| 4.907e-03 | -5.32 | CWC27 (CWC27 spliceosome associated cyclophilin) | protein interactions | 10283 | 61 | 27 | 19454 | 5460 |
SIPA1L1,ATG16L1,DHX38,HEXIM1,NUPR1,LMNA,CBX3,MAD2L1BP,LSM2,CLK1,RPA3,CAMKV,STAU1,HMGA1,MYC,MORF4L1,FRA10AC1,UBE2H,DDX23,LMNB1,LSM6,YWHAZ,SYT2,ZNF330,EIF4A3,PDCD5,VTI1B |
| 4.907e-03 | -5.32 | GEMIN7 (gem nuclear organelle associated protein 7) | protein interactions | 79760 | 61 | 27 | 19454 | 5460 |
HAX1,RCL1,SHC1,STK24,SNRNP70,GEMIN8,TUSC1,SNRPB,DDRGK1,CUL3,ESR2,SNRPD3,SNRPD1,ADD1,PHAX,SNRPD2,RPLP1,FEZ1,KLC2,SNRPE,EZH2,TUBA1A,AURKAIP1,DUSP14,IMMP2L,SNRPG,SMN1 |
| 4.907e-03 | -5.32 | SNX33 (sorting nexin 33) | protein interactions | 257364 | 61 | 27 | 19454 | 5460 |
PAK2,SDC2,FASLG,RAF1,TULP3,FNTB,HNRNPK,CMAS,PTGES3,TXNDC17,PRKD3,ALKBH4,SNX33,YWHAZ,ZNF575,NCKIPSD,ZCCHC10,MYC,YWHAH,YWHAG,FBXO7,PRNP,SNX18,OCRL,VIRMA,FCHSD2,DNM2 |
| 4.908e-03 | -5.32 | positive regulation of ERK1 and ERK2 cascade | biological process | GO:0070374 | 199 | 76 | 18204 | 5365 |
CCR1,MAP2K1,CD36,SEMA7A,SHC1,RAMP3,CHRNA7,NPY5R,RAP1B,TPBG,EPO,CHI3L1,NPSR1,DSTYK,NRP1,TIRAP,PLA2G5,FGF1,FGF23,GPBAR1,CCL19,NTRK2,MIRLET7B,NTRK3,MIR519D,CRKL,CD4,MIR21,CCL21,DDR1,PRKCA,GLIPR2,TNFAIP8L3,GNAI2,GPNMB,RAP1A,MIR126,FERMT2,PHB1,MT3,ACTA2,TNF,DNAJC27,IGF1,NOTCH2,ALKAL1,IL1A,CX3CL1,MIR24-1,AKAP12,ICAM1,MAP3K12,CCR7,PTPN11,FBXW7,PHB2,TLR4,OR2AT4,AGER,HAND2,OPRM1,MIR23A,HRAS,PYCARD,MIF,PTPN22,PDE8A,CCL3,P2RY1,ACKR3,HMGB1,ANGPT1,DDT,HTR2A,ADRA1A,SRC |
| 4.923e-03 | -5.31 | DoH | smart domains | SM00664 | 4 | 4 | 9717 | 2575 |
DBH,FRRS1,FRRS1L,MOXD1 |
| 4.925e-03 | -5.31 | COMMD7 (COMM domain containing 7) | protein interactions | 149951 | 26 | 14 | 19454 | 5460 |
COMMD6,VPS26C,CNKSR3,COMMD2,IKBKB,STMN2,FAS,COMMD9,CCDC22,COMMD8,CHRM3,COMMD3,INSYN1,COMMD5 |
| 4.925e-03 | -5.31 | Csk (c-src tyrosine kinase) | protein interactions | 12988 | 26 | 14 | 19454 | 5460 |
PTPN22,SH3GLB1,CSK,HMGA1,ZNF668,COX11,CAMK2G,AFTPH,TSC22D3,UQCRC2,PYM1,HOMER3,QSER1,TRIM21 |
| 4.925e-03 | -5.31 | PGGT1B (protein geranylgeranyltransferase type I subunit beta) | protein interactions | 5229 | 26 | 14 | 19454 | 5460 |
PDE12,KRAS,RRAS2,STAT6,CBL,RHOB,FNTB,EHD1,DDX39A,GNG2,CDC42,ATG7,RIOX2,PTAR1 |
| 4.925e-03 | -5.31 | DEFB127 (defensin beta 127) | protein interactions | 140850 | 26 | 14 | 19454 | 5460 |
LMNA,DCTN4,FCER1G,MFSD14B,ASZ1,FAM174A,AURKAIP1,ACTR1A,PIANP,COPS5,HTRA1,DCTN6,ACTR1B,DCTN3 |
| 4.925e-03 | -5.31 | SSC5D (scavenger receptor cysteine rich family member with 5 domains) | protein interactions | 284297 | 26 | 14 | 19454 | 5460 |
CDC42SE2,DDX39A,NUP62,BIRC5,MED29,SDCBP,MED21,SKA1,BLOC1S2,TCEA2,KLHL23,TRAF1,UQCRH,MED11 |
| 4.925e-03 | -5.31 | CERS5 (ceramide synthase 5) | protein interactions | 91012 | 26 | 14 | 19454 | 5460 |
MACO1,CNPY3,HMGCS1,SEC62,CCR6,P2RY12,LMBR1L,CXCR4,HCAR1,CD83,BSCL2,NPTN,LPAR1,TACR3 |
| 4.925e-03 | -5.31 | BMP2 (bone morphogenetic protein 2) | protein interactions | 650 | 26 | 14 | 19454 | 5460 |
GREM1,FBXO11,MGP,SOSTDC1,BMPR1A,NOG,GREM2,SNX18,BMPR1B,TGFB2,RGMB,ACTR2,BMPR2,ACVR1 |
| 4.925e-03 | -5.31 | CRADD (CASP2 and RIPK1 domain containing adaptor with death domain) | protein interactions | 8738 | 26 | 14 | 19454 | 5460 |
CCSER2,ERG28,TRIM54,KCTD9,HNRNPL,LRIF1,WIF1,MYC,EEF1A1,TSHR,CRYAB,BBS5,PTGER4,KPNA1 |
| 4.926e-03 | -5.31 | NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic) | protein interactions | 10101 | 165 | 62 | 19454 | 5460 |
COIL,HSCB,SRSF2,AKAP1,STAT6,PIH1D1,HEXIM1,GALNT1,CNP,MAD2L2,DTWD1,APEX1,MAD2L1,TUBB,PSMD6,PSMD4,GNPDA1,GGT7,FAM91A1,CCNF,GAB1,STUB1,RIT1,HERC4,UBE2H,PFDN6,H2AZ2,FAS,BAG3,TUFM,AR,BTF3,CUL3,CPLX1,RIGI,PFDN1,KRAS,EPHA4,CDK5,PSME1,RNASEH2C,RAD23B,ZRANB2,PRKAG1,RPN1,UBR7,SOX2,APOO,TUBA1A,HEXA,RAF1,EGLN3,PAIP1,IGBP1,ACSL4,CD58,UCK1,PTGER4,CIAO3,LAMP2,MDFI,MICB |
| 4.926e-03 | -5.31 | WDHD1 (WD repeat and HMG-box DNA binding protein 1) | protein interactions | 11169 | 165 | 62 | 19454 | 5460 |
EP300,NUP50,SLU7,RPA3,NBN,UPF3B,PSMC1,GINS3,GREM2,SMC4,CD2AP,TPT1,FOXS1,RPA2,S100A6,MAD2L1,DYRK1A,VIRMA,ESR2,MATR3,PSMD4,ADRM1,RBBP4,PTPN11,RIT1,RBBP8,BRCA1,PCNA,BAG2,MCM6,PHF1,MSH6,IMMP2L,SSRP1,CA10,AKAP12,KPNA2,ACTR1A,ZMYM3,GTF2E2,NETO2,IMP3,PPP4C,SMARCB1,MOB3C,CDK8,GINS4,CCDC71,EEF1AKMT3,MGME1,EGLN3,FZR1,RPL35A,PRNP,SPMIP5,SUMO2,XPO1,PIK3R1,PDIA3,KPNA1,MAP4,DDX23 |
| 4.926e-03 | -5.31 | RASA1 (RAS p21 protein activator 1) | protein interactions | 5921 | 165 | 62 | 19454 | 5460 |
MET,CAV2,JUP,WWP1,FGFR1,MRPL10,SYK,ARHGAP1,MLH3,STAU1,HSPA8,RAB5A,BMPR1A,EPHA2,SMAD2,STK11,IVNS1ABP,AR,CSK,ACAP2,SRC,TMOD3,ACTB,YES1,DOK4,GAB1,MRPL53,NFKBIA,SPRY1,PDE6D,BIRC5,SNRPE,EZH2,SOCS3,RAP1A,MRPL11,PRPS1,CAPZA1,KIT,AKAP12,KRAS,G3BP1,PRPSAP1,IGF1R,HSPD1,SPSB1,SLC25A5,HSPB1,DRG1,MRPL18,ARHGAP5,BCL10,NCK1,SHC1,PIK3R1,WWP2,MRPL24,AFAP1L2,HNRNPL,CORO1C,RB1,HRAS |
| 4.944e-03 | -5.31 | exogenous protein binding | molecular function | GO:0140272 | 82 | 36 | 18094 | 5411 |
SLC20A2,CCR5,ICAM1,CD4,CD81,PLSCR1,CLDN9,SLC7A1,HYAL2,CXCR4,RPSA,MRC1,CD46,ITGA2,CD86,SIVA1,DPP4,CD80,ALB,TFRC,DAG1,HTR2A,IDE,CD209,MOG,NECTIN2,CDK1,CLDN1,GPR15,ITGB5,CLDN6,EPHA2,F11R,ITGAV,LDLR,TNFRSF14 |
| 4.952e-03 | -5.31 | Hurthle_cell_adenoma | COSMIC cancer mutations | Hurthle_cell_adenoma | 28 | 15 | 16828 | 4835 |
TFG,TRIM24,MET,AKT1,PIK3CA,TERT,TPM3,PTEN,KRAS,HRAS,IDH1,TRIM27,MAP2K1,GOLGA5,SMAD4 |
| 4.952e-03 | -5.31 | thyroid-adenoma-nodule-goitre-Hurthle_cell_adenoma | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre-Hurthle_cell_adenoma | 28 | 15 | 16828 | 4835 |
MET,TRIM24,TFG,AKT1,TERT,PIK3CA,PTEN,TPM3,HRAS,KRAS,TRIM27,IDH1,MAP2K1,SMAD4,GOLGA5 |
| 4.961e-03 | -5.31 | human chr20q13.12 | chromosome location | human chr20q13.12 | 93 | 32 | 26134 | 5823 |
SEMG2,CTSA,SDC4,PKIG,PABPC1L,TTPAL,WFDC5,OSER1,SERINC3,ELMO2,RIMS4,PI3,FITM2,STK4,MATN4,MYBL2,YWHAB,WFDC13,DNTTIP1,CD40,SLPI,GDAP1L1,TNNC2,MMP9,SPATA25,TP53TG5,IFT52,KCNS1,SYS1,NEURL2,NCOA5,ACOT8 |
| 4.965e-03 | -5.31 | regulation of cell junction assembly | biological process | GO:1901888 | 217 | 82 | 18204 | 5365 |
TNF,GPM6B,LRRTM1,SDC4,DUSP3,SMAD3,MMP14,NLGN1,DUSP22,ROCK2,ROCK1,CTNNB1,FERMT2,SLITRK5,SLITRK2,SFRP1,RAP1A,LRRTM2,OXTR,LRRTM3,MIR142,NEGR1,CORO1C,SETD5,WNT7A,FAM107A,DKK1,EPHA2,SRC,NTNG2,IL1B,POLDIP2,S100A10,SYNDIG1,LRRC24,FLOT1,THY1,GREM1,APLNR,SNAP25,GPC4,DAPK3,IL1RAP,TPBG,PTEN,CAV1,MIR105-1,IKBKB,GPBAR1,NRP1,SLITRK1,ASIC2,VEGFA,LRRC4B,LRFN3,MEF2C,ADNP,EFNA5,RAP1B,CHRNB2,RAP2A,GHRL,F11R,CRB3,TLR2,GPRASP3,NLGN2,AMIGO1,LDB1,FLRT3,LRTM2,ARF6,FLRT2,CLDN3,SNAI2,CBLN2,CLSTN3,NTRK2,CLDN1,CBLN1,LRRN1,LHFPL4 |
| 4.972e-03 | -5.30 | reactive oxygen species degradation | BIOCYC pathways | HUMAN_DETOX1-PWY-1 | 10 | 8 | 902 | 319 |
GPX6,GPX7,GPX1,SOD2,SOD1,SOD3,GPX2,GPX3 |
| 4.977e-03 | -5.30 | CLINT1 (clathrin interactor 1) | protein interactions | 9685 | 196 | 72 | 19454 | 5460 |
BET1,ATG16L1,CFTR,CDKN1A,PPP1CB,GABRA1,PICALM,FGFR1,RPA2,STAMBP,ARL15,RPS28,PML,RPA3,EP300,RAB9A,STAU1,STX7,CUL3,RAB11A,MAP3K21,BICD2,MYO6,LAMTOR1,UBE2H,HTRA2,AP2A1,NTRK3,SMAP2,ARF1,LMBR1L,AP2M1,DYNLL1,ATP6AP2,RAF1,KBTBD4,CSTF2T,GABARAPL1,JUN,MAP1LC3B,ISG15,RAB4A,CAPZA2,NUPR1,AP1S2,HNRNPA2B1,SCYL2,STX8,EWSR1,KRAS,TFG,IMMP2L,ARF4,RAB5C,PFDN5,ATG9A,LAMP2,LAMP3,YWHAH,YWHAG,XPO1,NCK1,MAP4,DNAJC7,STAMBPL1,MED4,MAP1LC3A,VTI1B,ARF6,CDC5L,STX6,EGLN3 |
| 4.978e-03 | -5.30 | positive regulation of protein import into nucleus | biological process | GO:0042307 | 40 | 20 | 18204 | 5365 |
LEP,PSEN1,HYAL2,HSP90AA1,EFCAB7,DMAP1,IFNG,CDK1,SMAD3,MAVS,BAG3,JUP,PIK3R2,JAK2,HCLS1,HDAC3,RAN,PIK3R1,EP300,RBM22 |
| 4.978e-03 | -5.30 | fear response | biological process | GO:0042596 | 40 | 20 | 18204 | 5365 |
NEUROD2,DBH,ASIC1,DRD1,ADRB1,SLC1A1,DPP4,EIF4E,CRHR1,ATP1A2,GNG7,COMT,EXT1,BRINP1,NR2E1,VDAC1,MECP2,USP46,LARGE1,HTR1A |
| 4.981e-03 | -5.30 | PFKM (phosphofructokinase, muscle) | protein interactions | 5213 | 162 | 61 | 19454 | 5460 |
EGLN3,CDC5L,FAM98A,SUMO3,RHOH,SUMO2,FBXO32,DUSP6,PHB1,DNAJC7,HAX1,FOXP1,RHOG,HDAC6,UBXN6,MOV10,DCP2,PCNA,EMC2,MAP1B,POLR2C,HGS,APEH,RHOBTB1,EZH2,CAPZA2,CHMP4C,TUBA1A,EEF1A1,MAP1LC3B,RAF1,TP53,UBTD1,FERMT2,SFRP4,VIRMA,HPF1,RHOJ,SIAH1,DYNLL1,ANAPC2,CCNF,MIDEAS,NTRK3,UBE2H,LAMTOR1,BRCA1,CAV3,GGH,NONO,MYC,CUL3,HSPA8,ARFIP1,SQSTM1,RHOU,RPA3,PICALM,CDC42,RND2,PGRMC1 |
| 4.988e-03 | -5.30 | DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1) | protein interactions | 51143 | 221 | 80 | 19454 | 5460 |
EIF4B,HEXIM1,CZIB,DCTN4,RPA2,PSMB7,FTH1,PPP1CB,CDC42,PAFAH1B1,TPT1,TOMM22,STAU1,HNRNPA0,PDHB,LCP1,SQSTM1,DCTN3,ARPC2,MAVS,DDX5,WBP2,RPA3,BAP1,UBE2H,MAPRE1,BICD2,YWHAZ,CUL3,MYC,ESR2,PSMB6,DYNLT3,TSN,ADRM1,DYNLL1,ACTB,RPS12,DLST,FAM91A1,LMBR1L,RAB4A,CAPZA2,TUBB4B,RPS7,NUDCD3,ACTR1A,ACTN4,MGARP,TXNRD1,MACO1,TFG,CAPZA1,EIF3E,WASL,AKAP12,DYNC1I1,PSMA1,ACTR1B,SEPTIN7,TSNAX,YWHAB,POU5F1,SPHK2,H2AC4,ESYT1,EDC3,KLHL22,WDR11,CDC5L,EGLN3,DYNC1I2,RAB1B,OCRL,MTAP,ATP6V1A,C2CD2,PHB1,FBXO32,PTPN1 |
| 4.997e-03 | -5.30 | carboxylic acid metabolic process | biological process | GO:0019752 | 787 | 265 | 18204 | 5365 |
DEGS1,ADIPOR2,AUH,SEPHS2,PTGES,PLA2G4B,ABHD10,ACAA2,ALDH1L1,ABHD6,IER3,NANP,HEXA,HACD2,IDH3A,SUCLG2,MMUT,ACSL4,CYP27A1,CYP4F8,TPH2,SLC1A3,CYP2F1,GLYAT,PPARA,UST,ACADSB,GNMT,VDAC1,ERRFI1,MBLAC2,OAT,DLAT,HTR2A,ENO1,MORC2,MIF,CYP26A1,IREB2,ACOT6,PRKAG1,IDH3B,SLC25A17,ST3GAL1,PNPLA8,CD36,CMAS,LDHB,NUDT19,ASRGL1,ODC1,CRAT,PHYH,ELOVL7,SLC25A42,ADSS2,PC,GFPT1,HADH,CYP4F22,ETFA,MDH1,SLC6A8,RIMKLB,EPHX1,OGDHL,HACD3,BRCA1,MTAP,ABHD12,MGST2,CYP2D6,PCK2,CPT1B,ACADS,GPX1,CPT2,GPT,LIAS,GSTP1,CRTAP,SLC2A3,OSBP,ASPA,HSD17B10,CRYL1,UCP2,IGF1,DPEP1,FKRP,PFKFB2,ADTRP,PCCB,PDHB,ACO1,HACD4,PLA2G15,PEX13,SEPHS1,PGAM1,GSTM2,AMACR,FMO1,PYCR2,LDHA,SLC5A6,GCLC,ACACA,IDH1,SCPEP1,EGLN2,AKR1A1,GAD2,PLA2G5,ILVBL,KGD4,LDHAL6B,RIMKLA,CYP2C8,CYP1A1,P4HA2,ATP1A2,PLAA,TST,GAMT,TECR,RGN,GPX4,XBP1,AZIN1,EHHADH,DBT,CYP39A1,GNPAT,CSGALNACT1,DLST,DECR2,PEDS1,LYPLA2,PGM1,CYGB,ACBD7,ST6GAL1,TP53,HADHA,GMPS,IDO1,SERINC3,FADS2,ACCS,ELOVL3,HSD17B8,IDH2,LEP,UGT2A3,ATF4,UGDH,SORD,FAHD1,ENO2,ADH1B,ACO2,AIG1,GGTA1,ACSS2,SCD5,NDUFAB1,COMT,UGT1A1,SLC25A21,CRABP2,PTGES3,MTHFD2L,LYPLA1,HEXB,MGST3,AASDHPPT,PPM1K,PYCR1,CYP2C18,SLC38A1,MECP2,HACD1,ETFB,CYP4V2,GAPDH,AKR1C1,PTGDS,HNMT,GNPDA2,AKR1C2,ABHD2,NUDT7,CRYM,DDAH2,PPARG,ASNSD1,LIPA,ACOX1,SLC16A1,CYP7A1,ELOVL4,PGK1,GSTO1,FAH,SLC25A12,SLC25A32,SESN2,ADH1A,GSTA1,CDO1,GSTO2,GNPDA1,FA2H,EGLN3,SLC23A2,PRKAB1,GLUL,GPAM,ADIPOQ,SLC2A1,SHMT1,MCAT,PCBD1,ADIPOR1,PYCARD,ABHD5,AKR1B1,BCKDK,SDS,MSMO1,DDAH1,CYP3A5,PPAT,CYP4F12,SYK,MGAT4A,ELOVL1,ALOX5AP,LIPT2,ECHDC1,PLP1,GGT7,RDH10,ARG2,HPGDS,ELOVL6,CYP2C9,CBR4,MPST,SLC25A44,FOLR1,ACOT8,ACAT1,BPGM,MECR,AMT,ALDH1A3,CYP1B1,NDP,TLR2,AZIN2,PDHA1,MTHFS,GSTM4 |
| 5.000e-03 | -5.30 | response to prostaglandin E | biological process | GO:0034695 | 25 | 14 | 18204 | 5365 |
CCL21,GNB1,PAX6,P2RY4,GNG2,AKT1,CCR7,AANAT,SFRP1,PRKCE,CCL19,PTGER2,ACACA,PTGER4 |
| 5.000e-03 | -5.30 | N-terminal protein amino acid modification | biological process | GO:0031365 | 25 | 14 | 18204 | 5365 |
CREBBP,NAA50,AANAT,NAA60,METAP1,PPM1B,NAA35,NAA11,NAA16,PDF,METAP2,NTMT1,NAA15,EP300 |
| 5.000e-03 | -5.30 | decidualization | biological process | GO:0046697 | 25 | 14 | 18204 | 5365 |
VDR,GJB2,DEDD,PTN,GHRL,STC1,JUNB,NDP,CTSB,TPPP3,PARP2,SPP1,CYP27B1,TCF23 |
| 5.000e-03 | -5.30 | nuclear membrane reassembly | biological process | GO:0031468 | 25 | 14 | 18204 | 5365 |
REEP3,CHMP2A,CHMP1B,CHMP5,NSFL1C,VPS4B,UBE2I,CHMP4C,CHMP2B,UBXN2B,VPS4A,BANF1,CHMP1A,REEP4 |
| 5.000e-03 | -5.30 | protein refolding | biological process | GO:0042026 | 25 | 14 | 18204 | 5365 |
HSPD1,HSPA8,HSPB6,HSPA13,FKBP1A,HSPA5,DNAJB2,HSPB2,HSPB1,CRYAB,FKBP1B,HSPA14,B2M,HSP90AA1 |
| 5.001e-03 | -5.30 | MEX3C (mex-3 RNA binding family member C) | protein interactions | 51320 | 84 | 35 | 19454 | 5460 |
AP2A1,LMO2,PRPF19,CUL3,YWHAH,XPO1,CCAR2,UBE2L3,ESR2,AIFM1,STUB1,WDR6,UBE2N,UBE2S,ALYREF,AP2M1,PTEN,GLE1,ILF2,ZNF574,NUFIP2,GTPBP1,RAF1,SOX2,DDX39A,SOCS3,EEF1A1,PPP2R1A,UBE2V1,CNOT7,UBE2D3,RIGI,HSPA5,PABPC1,DHX9 |
| 5.001e-03 | -5.30 | NACC1 (nucleus accumbens associated 1) | protein interactions | 112939 | 84 | 35 | 19454 | 5460 |
PSMD7,LGALS8,ZBTB38,LSM3,CUL3,CCNB1,MYC,XPO1,PRPF18,POLR2L,SRP14,UBE2I,FOXP3,CDK8,CBX3,ENC1,EZH2,NACC2,ZBTB42,RBPJ,EHHADH,TBK1,GREM2,ZBTB14,HDAC3,BCL6,COIL,MATN4,ZBTB6,PML,BAP1,RPA3,MAVS,NUP50,NDUFC2 |
| 5.001e-03 | -5.30 | NELFA (negative elongation factor complex member A) | protein interactions | 7469 | 84 | 35 | 19454 | 5460 |
RPA2,POLR2C,SUPT5H,TP53,UBR7,ASF1A,SEM1,SSRP1,COIL,TCEA2,PML,PYM1,RUSF1,RPA3,ELOF1,PICK1,YWHAZ,YWHAB,RIT1,ICA1,ATP1A1,OPRM1,WWP2,MYC,AR,SIAH1,KCTD10,POLR2I,ESR2,NCBP2,POLR2B,SRSF1,FEZ1,POLR2F,INTS12 |
| 5.001e-03 | -5.30 | STK32C (serine/threonine kinase 32C) | protein interactions | 282974 | 84 | 35 | 19454 | 5460 |
PSMB4,FAM210A,CDIPT,PTPMT1,HNRNPL,BUB3,MRPL24,HSP90AB1,ABHD12,CACYBP,POLR2B,TECR,ILVBL,ISYNA1,IQSEC1,PSMD7,FKBP4,SDF2L1,ATP5MC1,ATP1A1,HSP90AA1,ATP5MK,NDUFA4,SLC25A10,SQSTM1,HADHA,SLC16A1,SMC4,FKBP8,TOP3B,CNP,ASPM,SSR1,FDFT1,HGS |
| 5.013e-03 | -5.30 | regulation of developmental growth | biological process | GO:0048638 | 314 | 114 | 18204 | 5365 |
MIR873,PIK3CA,FOXP1,PAFAH1B1,MAEL,STK4,MIR1-1,CREB1,SOCS2,SYT2,HNF1B,CRABP2,SASH3,FGFR1,PPIB,CDK1,GHR,ADRB1,MIR590,HEY2,TOMM70,LEP,STK3,PPARA,SLC6A4,SIN3A,FOXS1,MECP2,MKKS,MIR204,BMPR1A,SEMA7A,VEGFA,BMPR2,VGLL4,CAV3,MSTN,EFNA5,MEF2C,IL7,SMURF1,CDKN1B,MIR548C,HDAC3,ZMPSTE24,RUNX1,RTN4,MIR208A,HTRA2,DNM2,PLCB1,PI16,ANAPC2,SYT4,FXN,MTM1,DIO3,SLC6A3,TTL,IGF1,MBD5,RBPJ,PARP2,MUL1,MAP1B,GPAM,GH1,WNT2,SLC23A2,MT3,NPY1R,SPP1,RGS2,MIR25,CDK5,AKT1,CXCL12,PLAC8,SAV1,TRIM46,AGR2,HDAC6,CXCR4,NOG,SEMA5A,DUSP10,ADRB2,PROX1,DISC1,PTEN,DUSP6,NPPC,NRP1,CDKN1A,GSK3A,L1CAM,FOSL2,ADNP,FGF13,CTTN,RGMA,GHRL,ADRB3,MIR222,G6PD,TNR,FOXC2,PLAA,GAMT,STAT5A,AR,RND2,SOD1,IFRD1 |
| 5.022e-03 | -5.29 | macromolecule transmembrane transporter activity | molecular function | GO:0022884 | 32 | 17 | 18094 | 5411 |
SEC63,ABCC5,SEC61A1,MCL1,PEX13,TIMM23,SEC61A2,TOMM70,BLOC1S3,AZGP1,TOMM40,SEC61G,TOMM40L,TOMM7,TIMM17A,TOMM22,TOMM20 |
| 5.027e-03 | -5.29 | Signaling by FGFR in disease | REACTOME pathways | R-HSA-1226099 | 63 | 30 | 10285 | 3229 |
POLR2B,NCBP2,ZMYM2,FGF17,FGF10,FGF3,TRIM24,FGFR1OP2,POLR2D,POLR2L,FGF22,ERLIN2,STAT5A,POLR2F,GTF2F2,POLR2G,KRAS,FGF7,FGF1,FGF16,PIK3R1,POLR2I,GTF2F1,PIK3CA,STAT1,HRAS,GAB1,FGFR1,FGF23,POLR2C |
| 5.027e-03 | -5.29 | Synthesis of substrates in N-glycan biosythesis | REACTOME pathways | R-HSA-446219 | 63 | 30 | 10285 | 3229 |
GFPT1,GMPPA,ST3GAL5,NANP,ST6GALNAC3,SLC35A1,GFUS,ST3GAL1,SRD5A3,MVD,PMM2,CMAS,DPM2,NEU1,UAP1,CTSA,ST8SIA4,FPGT,ST6GAL1,ST3GAL4,DOLK,GMPPB,NUS1,SLC35C1,ALG5,GMDS,ST8SIA5,GNPNAT1,ST3GAL2,SLC17A5 |
| 5.036e-03 | -5.29 | PVR (PVR cell adhesion molecule) | protein interactions | 5817 | 159 | 60 | 19454 | 5460 |
PLPP6,RFC3,PAEP,TNFSF8,USP30,ADIPOQ,EFNB1,RAB13,PGA4,TMEM147,RUSF1,GPD2,CTNNA2,SFTPC,ALG11,CBLN4,TNPO2,TP53,MTCH2,INSIG2,HNRNPL,ANKRD46,KCTD10,XPO5,GNPAT,ITGA6,ZDHHC15,PPM1B,LANCL2,CD81,FAM20B,TMBIM6,MICB,CD200R1,TSPO,NINJ1,HELLS,TMEM106B,RETREG2,SYS1,PLP2,TSHR,CTXN3,EDDM3B,DYNLT3,ALG5,RABIF,LGALS3,CD47,TMEM229B,LMBR1L,METAP2,KRTAP3-1,NECTIN2,NTRK3,CD226,SLC35B4,HMOX2,PTPN11,VAMP5 |
| 5.057e-03 | -5.29 | myxoid | COSMIC cancer mutations | myxoid | 16 | 10 | 16828 | 4835 |
TFG,KRAS,RB1,HRAS,IDH1,SS18,TERT,EWSR1,PTEN,SMARCB1 |
| 5.077e-03 | -5.28 | TNPO2 (transportin 2) | protein interactions | 30000 | 218 | 79 | 19454 | 5460 |
PTP4A3,CD274,NCR3LG1,FXYD6,SNRNP70,H2AC4,CD200R1,MOV10,TRIM8,LRRC4,FAM174A,P2RY10,DLK2,XPO1,COPS5,TMA16,HNRNPA1,TPM3,CAMK2G,CD80,G3BP1,SEMA4C,RUVBL1,THRAP3,AHCYL1,MSH6,MAP1B,CD83,GARRE1,GLCE,EFNB1,CA14,SIGLECL1,TUBB4B,AQP3,NME1,CYB5B,ADORA3,OTX2,COMTD1,TNRC6C,PNMA5,RANBP1,LPAR6,NUP153,TUBB,SCN2B,DPEP1,RAN,TUBA1B,CHRM4,SYNGR1,TMEM108,DCAF4,SERTAD3,NRP1,PYCR1,CUL3,VAMP5,GPR17,EXOC5,KDM1A,NPTN,RPL4,RP2,RNF11,PACSIN3,CD40,BAP1,SF3B1,CRYAB,RPRD1B,LARP4B,THAP6,KLHL3,ATG16L1,FAM234A,HCST,KRTAP8-1 |
| 5.083e-03 | -5.28 | vascular transport | biological process | GO:0010232 | 86 | 37 | 18204 | 5365 |
CD36,KCNJ8,SLC1A2,SLC38A2,SLC1A1,SLC38A1,AVPR1B,SLC2A3,TFRC,SLC4A8,LEPR,ABCC5,SLC2A1,NHERF1,ATP8A1,ATP2B4,LRP3,FABP5,SLC7A1,ABCB1,SLC15A2,SLC16A1,ABCG2,SLCO3A1,SLC29A1,SLC1A3,ATP1A2,AGER,SLC22A8,SLC6A1,SLC5A6,SLC6A6,SLC7A8,ABCC2,SLC38A3,SLC12A2,SLCO2B1 |
| 5.083e-03 | -5.28 | transport across blood-brain barrier | biological process | GO:0150104 | 86 | 37 | 18204 | 5365 |
ABCG2,SLC16A1,SLCO3A1,SLC29A1,SLC15A2,AGER,ATP1A2,SLC1A3,SLC7A8,SLC6A6,SLC5A6,ABCC2,SLC22A8,SLC6A1,SLCO2B1,SLC12A2,SLC38A3,AVPR1B,SLC38A1,SLC1A1,SLC2A3,SLC1A2,KCNJ8,CD36,SLC38A2,LEPR,SLC4A8,TFRC,NHERF1,ATP8A1,ATP2B4,ABCC5,SLC2A1,ABCB1,LRP3,FABP5,SLC7A1 |
| 5.085e-03 | -5.28 | TJP2 (tight junction protein 2) | protein interactions | 9414 | 278 | 98 | 19454 | 5460 |
SUMO1,SNAI3,SIPA1L1,CD2AP,EDF1,CFTR,RPA2,NUDT12,SNAI2,WWP1,STX17,ACACA,RPA3,SIRT7,CLK1,PGK1,HMGB1,FBXW7,HSPA5,CSK,CCNB1,ARHGAP21,ANAPC15,BICD2,STK24,UBE2H,CCNF,NECTIN2,EZH1,CTNNA1,UBN1,CHMP5,IFI6,VIRMA,SRPK2,DYRK1A,H2AJ,JPH4,RPAP2,ARHGAP12,ZMYM3,IFT57,DISC1,PALM2AKAP2,VRK1,UQCR11,AGPAT1,UBP1,CDK6,ARF6,PRNP,PTP4A3,EFHD1,MTMR6,GTF2H5,HSPA8,CLDN1,EIF1B,PSENEN,STAU1,MYC,SFN,BTF3,MCM4,MCM3,RHOB,YWHAZ,CCDC25,MATR3,MB21D2,FBXO22,SPCS1,RAF1,GDI2,CCR1,TMEM14B,HGS,RPL18,ZYX,BCKDK,LASP1,KRAS,G3BP1,UBE2A,MCM6,YWHAH,YWHAG,XPO1,CTNNB1,DDRGK1,DDX23,TRAF6,CBL,RASSF8,HSPB1,YWHAB,ANKRD50,GJA1 |
| 5.088e-03 | -5.28 | PPIL4 (peptidylprolyl isomerase like 4) | protein interactions | 85313 | 156 | 59 | 19454 | 5460 |
PAX6,MEPCE,EMC2,FAM76B,RPL23A,DDX42,TAF2,E2F4,RPSA,RAF1,TBK1,CSNK1E,ARHGAP12,CCAR2,TOP1,CDK9,ETV6,WDR82,DDX23,NDC80,PSMD3,DDRGK1,XPO1,TMA16,STAU1,FBXW7,COIL,ORC6,RPA3,EP300,RPA2,LMNA,TOX4,HECTD1,HEXIM1,NUFIP2,MFAP1,RBFOX2,SNRNP27,DENND2D,SMAD5,PPP1R10,CTTN,TACO1,CPSF1,CCNF,PSPC1,SF3B4,LMNB1,MECP2,UBE2H,RCL1,RIT1,CUL3,CIAO1,MYC,NONO,RBM15B,ARHGAP21 |
| 5.092e-03 | -5.28 | SLC2A2 (solute carrier family 2 member 2) | protein interactions | 6514 | 14 | 9 | 19454 | 5460 |
TRUB1,NUDT9,UFD1,CAPG,DVL2,CSK,ST3GAL2,HNRNPL,KPNA2 |
| 5.092e-03 | -5.28 | PGS1 (phosphatidylglycerophosphate synthase 1) | protein interactions | 9489 | 14 | 9 | 19454 | 5460 |
KRAS,PFDN5,OTULINL,HSD17B11,GABARAP,RIT1,AKAP1,PLD3,APEX1 |
| 5.092e-03 | -5.28 | ABTB1 (ankyrin repeat and BTB domain containing 1) | protein interactions | 80325 | 14 | 9 | 19454 | 5460 |
MTDH,DNTTIP1,DDX39A,CUL3,CARS1,APEX1,SMAD9,NTRK3,SMAD2 |
| 5.092e-03 | -5.28 | CSH2 (chorionic somatomammotropin hormone 2) | protein interactions | 1443 | 14 | 9 | 19454 | 5460 |
SCG5,GH1,SMAD3,HSPA5,SMAD2,SMAD9,SOST,CSH1,SMAD4 |
| 5.092e-03 | -5.28 | RN7SK (RNA component of 7SK nuclear ribonucleoprotein) | protein interactions | 125050 | 14 | 9 | 19454 | 5460 |
HEXIM1,MEPCE,CDK9,HNRNPA2B1,HMGA1,PPM1G,DHX9,HEXIM2,HNRNPA1 |
| 5.092e-03 | -5.28 | RHEBL1 (RHEB like 1) | protein interactions | 121268 | 14 | 9 | 19454 | 5460 |
SMAD2,SMAD4,ACVR1,TRAF2,FHL3,SMAD1,TXNL4A,AKT1,BMPR1B |
| 5.092e-03 | -5.28 | FRMD4A (FERM domain containing 4A) | protein interactions | 55691 | 14 | 9 | 19454 | 5460 |
CYTH4,TAX1BP3,HRAS,WDR83,YWHAG,HNRNPA1,SOX2,YWHAH,CYTH1 |
| 5.097e-03 | -5.28 | MYLK4 (myosin light chain kinase family member 4) | protein interactions | 340156 | 87 | 36 | 19454 | 5460 |
HSP90B1,RAD23B,MARCKSL1,UBLCP1,HMGB1,VDAC1,PTGES3,SOD1,PEBP1,APMAP,PGK1,PCNA,PDIA6,PRDX6,BLVRA,FKBP4,HSP90AA1,ATP1A1,MDH1,ZMPSTE24,MAT2A,PDIA3,CALR,LDHB,SUB1,PPIB,COPS5,TUFM,MCM4,ST13,ESD,TMPO,HSP90AB1,GANAB,RAP1B,MSN |
| 5.097e-03 | -5.28 | PAPOLA (poly(A) polymerase alpha) | protein interactions | 10914 | 87 | 36 | 19454 | 5460 |
CSTF3,TMPO,APEX1,CCNF,CPSF1,RSRC1,CORO1C,CIRBP,SMAD2,UBE2H,NIBAN2,CREBBP,HNRNPA1,UFD1,CPSF2,HDAC3,HUWE1,UGP2,RIGI,GNA11,ZYX,RPA3,BAP1,SNRPA,PABPC1,TGIF2,BAG2,YAF2,RPA2,LMNA,PICALM,TP53,SUPT5H,PPP1CB,CSTF2T,STXBP1 |
| 5.097e-03 | -5.28 | TCF25 (transcription factor 25) | protein interactions | 22980 | 87 | 36 | 19454 | 5460 |
FBXW7,CHCHD2,RIGI,PPAN,RPA3,RAB5A,LIPA,DERL1,APPBP2,SAT1,MAP2K1,RPA2,GPX7,AAMP,ELK4,TULP3,NEK2,AGO1,RPS10,FZR1,SELENON,ESR2,EGLN3,LMBR1L,PTEN,RC3H2,YWHAZ,DCAF5,TSNAX,YWHAB,HSP90AA1,RPS2,DDRGK1,GPRASP2,YWHAG,XPO1 |
| 5.097e-03 | -5.28 | XPO6 (exportin 6) | protein interactions | 23214 | 87 | 36 | 19454 | 5460 |
NPTN,EFNB1,VIPR1,CD40,RPA3,RUSF1,ATP2B4,CD83,CYB5B,SIGLECL1,CA14,NPY2R,SEC62,HCST,NUP62,FAM234A,TOP3B,COMTD1,ILVBL,DCUN1D1,ACTB,ZMAT2,LMBR1L,SCN2B,SMAD3,CD274,CHRM4,RAN,NCR3LG1,ATG7,P2RY10,STK4,VPS39,UBXN6,OPRM1,GPR17 |
| 5.107e-03 | -5.28 | establishment of RNA localization | biological process | GO:0051236 | 152 | 60 | 18204 | 5365 |
NUP35,UPF3B,DDX39A,TOMM20,XPOT,IGF2BP1,XPO5,MRPL18,SMG5,TNKS,NUP62,TST,TGFBR2,CASC3,NUP153,RBM15B,NUP50,BICD2,GLE1,ALYREF,RAN,ALKBH5,FYTTD1,CETN3,FXR2,RTRAF,NUP37,EIF4A3,SEC13,THOC1,EIF4E,NXT2,PHAX,DDX39B,MAGOHB,CETN2,NCBP2,ENY2,THOC6,RFTN2,POLDIP3,MAGOH,PEG10,G3BP2,HNRNPA1,MX2,NUP107,XPO1,THOC2,THOC3,SRSF7,ZC3H11A,PARP11,NUP42,HNRNPA2B1,FLOT1,CHTOP,NXT1,SRSF1,DHX9 |
| 5.123e-03 | -5.27 | E7 (early protein) | protein interactions | 1489481 | 50 | 23 | 19454 | 5460 |
PSMB1,H2BC12,TRUB1,RPL3,PCNA,PML,ENO1,STX8,ACKR3,MT2A,ACTB,CDKN1A,EEF1A1,AKIP1,IRF1,HNRNPAB,SELENOW,CD14,PDLIM4,PPIG,AP2A1,ZNF574,DNAL1 |
| 5.123e-03 | -5.27 | TUT1 (terminal uridylyl transferase 1, U6 snRNA-specific) | protein interactions | 64852 | 50 | 23 | 19454 | 5460 |
PRPF31,SNRPB,LSM3,RIT1,USP15,LSM6,SNRPD2,CPSF1,PRNP,LSM5,MED17,SNRPD3,SOX2,SNRPN,SART3,SNRPE,PRPF4,MEPCE,SNRPG,LSM4,HUWE1,KRAS,YTHDF1 |
| 5.123e-03 | -5.27 | NUB1 (negative regulator of ubiquitin like proteins 1) | protein interactions | 51667 | 50 | 23 | 19454 | 5460 |
SEM1,NEDD8,UBE2K,SEMA4C,RPA3,EP300,SQSTM1,TP53,SOX2,PSMD4,AIPL1,UBB,EGLN3,PSMB4,SF3B4,PSMC5,YWHAZ,LCN8,YWHAB,SFN,YWHAH,YWHAG,UFD1 |
| 5.123e-03 | -5.27 | GBP2 (guanylate binding protein 2) | protein interactions | 2634 | 50 | 23 | 19454 | 5460 |
SAT1,SQSTM1,GADD45A,SEPHS1,BNIP3L,TFG,HSPE1,SERPINB9,MVD,PPP1R8,CAPN1,TP53,CNDP2,ANXA7,LSM2,ADD1,CSNK2B,PAFAH1B3,G6PD,HSP90AB1,STK3,FBXO7,HSP90AA1 |
| 5.123e-03 | -5.27 | Cct4 (chaperonin containing TCP1 subunit 4) | protein interactions | 12464 | 50 | 23 | 19454 | 5460 |
DTL,CCT2,YWHAZ,GNB1,PDCD5,CCT7,TCP1,IGBP1,PTEN,VAMP3,PDCL,VAV2,ACTR2,ACTR1A,WDR77,CCDC47,CCT5,PPIL3,PFDN1,DNAAF10,SLC25A10,TXNDC17,CCT8 |
| 5.123e-03 | -5.27 | ZNF516 (zinc finger protein 516) | protein interactions | 9658 | 50 | 23 | 19454 | 5460 |
ASF1A,KDM1A,PAX6,PML,S100B,MED23,CTBP1,RPA2,KLF3,KLF4,ZBTB42,TOP3B,KLF12,PRNP,HYPK,APEX1,VIRMA,PHF21A,ZMYM2,ZBTB18,CSNK2B,DYRK1B,NOL4 |
| 5.129e-03 | -5.27 | regulation of cell-cell adhesion | biological process | GO:0022407 | 500 | 174 | 18204 | 5365 |
ACTL6B,CD47,SDC4,PIK3CA,IDO1,IFNG,IL21,CDSN,NKAP,PRDX2,IL18,SRC,ST3GAL4,KLF4,PTPN11,FGL2,THY1,LEP,CD40LG,LGALS3,IL15,C1QTNF1,EPO,MIR181C,SMARCB1,YTHDF2,IL23A,MIRLET7G,B2M,VEGFA,NF2,LRFN3,IL7,UBASH3B,F11R,TNFAIP8L2,IRF1,PRKCQ,GPNMB,CXCL13,EPCAM,ACTB,TWSG1,VSIR,TNF,ADIPOQ,CX3CL1,DUSP22,IL10,XCL1,GPAM,TESPA1,SELENOK,RPS3,TFRC,YES1,HMGB1,CD1D,SYK,HFE,CXCL12,BCL6,EMILIN1,PLG,PYCARD,AGER,DUSP10,IL2RA,TNFRSF14,ICOS,CCL2,FUT9,ARG2,RAG1,MIR141,CHST2,PRKCA,TRAF6,NLRP3,CCL25,MIR222,DPP4,CCR2,CCL19,AIF1,SFTPD,PDCD1LG2,CYRIB,TENM3,CTLA4,RHOH,CCL5,IL12B,SLC7A1,CSK,IL6,CD86,ACTL6A,SASH3,CD83,PNP,CD274,FOXP3,IL12A,HTR2A,HSPD1,BCL10,LILRB1,DHPS,PRNP,IL6ST,BTN2A2,SMARCE1,FLOT1,PPARA,PELI1,KLHL25,MAD2L2,IFNB1,CAV1,RC3H2,WNT10B,SWAP70,CD28,CD80,CBFB,EFNA5,SMARCD3,SOCS5,IL20RB,RUNX1,ZBTB16,MIR31,RGCC,JAK1,IL4,CD46,CD4,IFNA2,MIR21,MIR30B,CD9,CD81,LILRB4,MIR146A,EP300,IGF1,CD209,DUSP3,IL1A,NCK1,IL2RG,SPINT2,PPP3CA,PTPN22,SOX2,AKT1,IL1B,CCR7,ADTRP,JAK2,MIR125A,PLA2G5,CCL28,BAD,XBP1,CCL21,TNR,NDFIP1,TGFBR2,IL2,EFNB1,MIR221,DLG1 |
| 5.139e-03 | -5.27 | MKI67 (marker of proliferation Ki-67) | protein interactions | 4288 | 613 | 201 | 19454 | 5460 |
ACTN4,RPL29,PPP2R1A,MAK16,RAF1,SF3B5,CHMP4C,EZH2,SRSF8,JRKL,PPAN,TRIP4,EIF2D,FOXP4,MCM6,SRSF4,TRIM37,G3BP1,EIF3D,MAP3K14,STOML2,HAX1,HBA1,CDK5RAP3,MRTO4,RPL9,CGGBP1,ATXN10,NOP58,STXBP1,EHD1,ARCN1,IRF2BPL,USP39,CCDC86,G3BP2,UNC45A,COIL,YTHDF1,NOP53,MCM3,GGH,RPS29,RHEB,RAB11A,GRB10,CUL3,CBR3,RMI1,SP1,RPS5,BRCA1,POLR3B,RPL19,RPF1,MB21D2,RPL15,MAP1LC3B,YTHDF2,HINFP,DMAP1,ZC3H11A,TCOF1,NKRF,LTBR,SMN1,MDC1,TRIM63,HSPE1,CNOT7,CTNNBL1,PAK1IP1,ERCC3,H2AC14,MOV10,BRD3,MPHOSPH10,SRPRA,TOP1,THOC1,CDK7,SIPA1L1,CCND1,SHOC2,RPL26L1,LSM2,HSP90B1,PICALM,GRM2,TOX4,CDK1,LMNA,PPIH,PRKCB,SIRT7,RPA3,BRIX1,CXXC1,RPL4,MRPL17,NPM3,PPP1CC,RACGAP1,TAF5L,TADA1,PTEN,POP7,OPTN,VIRMA,RPL13A,NDN,LDHA,RPL18,TAF10,EWSR1,RPL31,RAB18,UTP6,CTNNB1,PPIB,DDX50,IFI16,CDC23,DRG2,FUBP3,LYAR,SUMO2,TCP1,ISG20L2,ZC3H14,TOMM22,HIRA,RPP14,STAU1,FXR2,RMI2,BTF3,MYC,APOBEC3B,NSA2,CDKL2,FTSJ3,MRPS25,VDAC2,RPL10,CBX5,ZCCHC7,SNRNP40,ZMYM4,H2AX,CENPM,RPSA,IMP3,NUPR1,HBP1,RBM34,IK,CBX3,CHAMP1,MAP1B,TOLLIP,CDC40,H3C1,RBM17,RPL10A,KPNA1,SNRNP70,ARL4D,RAP1B,RPL32,SYNCRIP,TMPO,RPS27L,CAND1,CDC42,SUMO1,SEPHS2,TFIP11,HBB,RPA2,DLAT,RNF113A,NLE1,WDR3,TIA1,VPS39,RPF2,RRP7A,MRPS16,MECP2,PTPMT1,QSER1,FGFBP1,TSSK1B,DYRK1A,RSL24D1,SRPK2,SMURF1,CDC20,CEP41,IRF2BP1 |
| 5.142e-03 | -5.27 | CCSER2 (coiled-coil serine rich protein 2) | protein interactions | 54462 | 64 | 28 | 19454 | 5460 |
TRIM36,DYRK2,DNAJC2,PICALM,EXOSC8,MAP1LC3B,PAFAH1B1,ATG16L1,STAU1,TCEA2,MAPRE1,YWHAB,STX1A,MYO6,YWHAZ,DCAF4,CRADD,EXOC1,YWHAG,YWHAH,SFN,VIRMA,EGLN3,SLMAP,DYNC1I2,RPGRIP1L,DYNLL1,KRT8 |
| 5.142e-03 | -5.27 | SURF2 (surfeit 2) | protein interactions | 6835 | 64 | 28 | 19454 | 5460 |
KBTBD6,MDM2,TOM1L1,B4GALT3,PRNP,TRIM27,HEXIM2,RPRD1A,CRTAP,ZCRB1,WDR20,FTSJ3,ZCCHC9,KPNA6,RIOX2,ANKMY2,DHPS,BRIX1,RPS13,NPTN,EP300,RPL3,PPME1,HEXIM1,ACTR2,RPRD1B,P3H1,H2AX |
| 5.142e-03 | -5.27 | TST (thiosulfate sulfurtransferase) | protein interactions | 7263 | 64 | 28 | 19454 | 5460 |
SEC22B,TIMM13,RPA2,IDH2,PNMA2,SOD2,UBE2M,FKBP1A,RPA3,SNRPA,PEBP1,NEDD8,RER1,DMPK,PSMB2,GSTK1,LYPLAL1,SMAD4,PSMD7,MT1X,NQO1,PRSS1,AIFM1,UBE2N,DSTN,CMBL,AKR1C2,MRPL50 |
| 5.142e-03 | -5.27 | ICE2 (interactor of little elongation complex ELL subunit 2) | protein interactions | 79664 | 64 | 28 | 19454 | 5460 |
NCBP2,RBM42,DYRK1A,SNRPB2,SNRPA1,RAP1B,SYNCRIP,CREB1,RPRD1A,VAMP3,ACTA2,RIT1,PSMD14,HP,DYRK1B,DSN1,FGFR1OP2,STX7,KRAS,NF2,STAU1,EMG1,PML,SIKE1,JCHAIN,SERPINA1,VPS33A,LARP4B |
| 5.142e-03 | -5.27 | SREK1IP1 (SREK1 interacting protein 1) | protein interactions | 285672 | 64 | 28 | 19454 | 5460 |
NUP153,DDX39A,THAP1,GTF2H4,DDIT4L,PRR13,RP9,SDCBP,FGF10,NME1,NKAPD1,FTL,KPNA2,CSNK2A1,KPNA6,DDRGK1,MYC,STAC3,KPNA1,UBE2H,NOS1AP,CSNK2B,MACROH2A1,GATAD1,RPL9,CCNF,NKAP,LYAR |
| 5.162e-03 | -5.27 | Signaling by Hedgehog | REACTOME pathways | R-HSA-5358351 | 138 | 58 | 10285 | 3229 |
SUFU,SMURF1,IFT52,GAS8,WDR19,SPOP,PSMD1,PSMB2,PSMA6,CSNK1A1,CDC73,IFT172,RPGRIP1L,PSMC1,CUL3,PSMD12,PSMC3,PSMA1,RPS27A,EFCAB7,PSMD4,PSME2,PSMB4,PSMD6,SEM1,PSMB9,PSMA4,TULP3,PSMA5,PSMB10,PSMC5,PSMB11,IFT57,ADCY2,PSMB6,PSMA2,PSMB3,PSMB7,PSMD3,PSMB1,OS9,ADCY3,PSMA3,HHIP,PSMB5,PSMC4,ERLEC1,DERL2,PSMD14,PRKACB,UBA52,UBB,SYVN1,PSMD10,PSME1,SPOPL,SKP1,PSMD7 |
| 5.168e-03 | -5.27 | Detoxification of Reactive Oxygen Species | REACTOME pathways | R-HSA-3299685 | 38 | 20 | 10285 | 3229 |
SOD1,GPX1,GPX6,SOD2,NUDT2,GPX2,GPX7,PRDX1,GSTP1,CCS,GPX3,PRDX2,GPX5,TXNRD2,PRDX3,SOD3,TXN,ERO1A,PRDX6,TXNRD1 |
| 5.181e-03 | -5.26 | GALNT2 (polypeptide N-acetylgalactosaminyltransferase 2) | protein interactions | 2590 | 90 | 37 | 19454 | 5460 |
LRTM2,EMC2,RPA3,RAB1A,TMEM106B,EMC1,CLEC12B,VDAC1,ISG15,CDC42,TMEM106A,TMEM59,CCL3,B3GNT2,FAM3C,LMNA,RPA2,SFTPC,STX5,LMBR1L,VDAC2,PTPN1,CYB5R3,SDC4,RMND1,VIRMA,FIBIN,HNRNPL,SLC25A4,PIANP,DLK2,GORASP2,GOLPH3L,FAM20C,ZMPSTE24,REEP6,HFE |
| 5.181e-03 | -5.26 | TRIM8 (tripartite motif containing 8) | protein interactions | 81603 | 90 | 37 | 19454 | 5460 |
MAGEC2,RNF41,MSL2,CDSN,TICAM1,UBE2D3,RNF113A,TRIM21,EWSR1,RNF181,RNF7,USP39,TNPO2,UBE2V1,CCNH,UBE2W,TP53,RNF141,HSP90AB1,USP5,SIAH1,TRIM15,MIF,DCUN1D1,GPX1,PTEN,TRIM24,RCHY1,CBL,RC3H2,TUBG1,UBE2D1,BRAP,USP2,TRIM8,CUL3,TNFAIP3 |
| 5.181e-03 | -5.26 | SEMG1 (semenogelin 1) | protein interactions | 6406 | 90 | 37 | 19454 | 5460 |
SLC39A7,UNC50,HACD1,SEMG2,FBXW4,CLU,RDH11,AZGP1,EYA3,POLL,PIK3R2,SOX2,PSMB9,NEK2,FTH1,RAF1,PRKCA,NUPR1,TPPP,EZH2,FKBP14,FOXP3,PHETA2,PTK7,ZNF330,TUBA1B,MAT2B,KLK3,ESR2,LYZL6,NYAP2,BAZ1B,SAV1,NXPH3,LSM14B,PRSS1,MSMB |
| 5.181e-03 | -5.26 | cerebellum development | biological process | GO:0021549 | 103 | 43 | 18204 | 5365 |
NCSTN,MAP2K1,ZNF365,TUBA1A,EZH2,COQ8B,PAX6,MTPN,KLHL1,MECP2,RPGRIP1L,UQCRQ,ARCN1,FZD4,CBLN1,SEMA4C,TRNP1,CRKL,PSEN1,OPHN1,HSPA5,LDB1,CNTN1,HNRNPD,IGF1R,RERE,GNPAT,KCNC1,LPAR1,TP53,PTPN11,NEUROD2,FCGR2B,PROX1,CDK5R1,CEND1,PDSS2,COMT,CLP1,WNT7A,SLC25A46,CDK5,HSPA8 |
| 5.187e-03 | -5.26 | RBMXL1 (RBMX like 1) | protein interactions | 494115 | 150 | 57 | 19454 | 5460 |
SRSF7,ZC3H11A,RUSF1,SNIP1,DPM2,MEPCE,SRSF4,VRK1,PAIP2B,LBH,KIAA0408,APOBEC3D,H2AJ,FBP1,TMEM14B,OTX2,ILF2,CHMP4C,GNPDA2,PRR3,SRSF1,SYNCRIP,PTP4A3,TPM3,NDC80,UQCR11,ANKRD50,SNRNP70,CRBN,DNAJC22,PSENEN,RBMS2,SOX21,PPP1CB,EHHADH,SUMO1,MTF1,PABPC5,FAM81A,HEXIM1,LARP4B,TRIM24,EZH1,ESR2,TCEAL7,SH3BGRL,IFI6,SPCS1,MATR3,PPP1CC,ANAPC15,HNRNPC,MYC,PEA15,ELAVL2,FBXW11,SPOP |
| 5.188e-03 | -5.26 | regulation of vascular endothelial growth factor receptor signaling pathway | biological process | GO:0030947 | 35 | 18 | 18204 | 5365 |
MIR200C,IL1B,MIR1224,NRP1,PTPN1,FZD4,HGS,PRKCB,NIBAN2,EMILIN1,MIR296,MIR10A,FGF10,GRB10,MIR10B,VEGFC,MT3,TMEM204 |
| 5.206e-03 | -5.26 | regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032645 | 18 | 11 | 18204 | 5365 |
IL1B,IL12B,IL17F,IL18,RIGI,PAEP,TLR9,SYK,CD80,LILRA2,IL23A |
| 5.206e-03 | -5.26 | response to misfolded protein | biological process | GO:0051788 | 18 | 11 | 18204 | 5365 |
UFD1,CLU,CAV1,HDAC6,UBE2W,STUB1,CUL3,SDF2L1,DERL1,KLHL15,RNF126 |
| 5.206e-03 | -5.26 | negative regulation of anoikis | biological process | GO:2000811 | 18 | 11 | 18204 | 5365 |
SNAI2,PTRH2,CAV1,CEACAM5,NTRK2,PIK3CA,ZNF304,SRC,TLE1,PIK3R3,MCL1 |
| 5.206e-03 | -5.26 | retrograde protein transport, ER to cytosol | biological process | GO:0030970 | 18 | 11 | 18204 | 5365 |
FAF2,DERL2,DERL1,HSP90B1,ERLEC1,SELENOS,OS9,SEC61B,HM13,UFD1,SYVN1 |
| 5.206e-03 | -5.26 | regulation of MHC class II biosynthetic process | biological process | GO:0045346 | 18 | 11 | 18204 | 5365 |
JAK2,TAF7,XBP1,IL4,IL10,IFNG,RFX5,TLR4,TMEM106A,RFXAP,RFXANK |
| 5.206e-03 | -5.26 | endoplasmic reticulum to cytosol transport | biological process | GO:1903513 | 18 | 11 | 18204 | 5365 |
HM13,SYVN1,UFD1,ERLEC1,SELENOS,OS9,SEC61B,FAF2,DERL1,DERL2,HSP90B1 |
| 5.231e-03 | -5.25 | positive regulation of cytokine production involved in inflammatory response | biological process | GO:1900017 | 30 | 16 | 18204 | 5365 |
MIR21,TLR4,KPNA6,IRF3,IL6,MIR324,TLR6,CLEC7A,TLR3,MIR675,MYD88,TICAM1,GPSM3,TNF,IL17F,MIR17 |
| 5.231e-03 | -5.25 | immunoglobulin production involved in immunoglobulin-mediated immune response | biological process | GO:0002381 | 30 | 16 | 18204 | 5365 |
CD40LG,BATF,EXOSC3,NBN,SHLD1,RNF8,STAT6,MSH6,CCR6,TRAF3IP2,SWAP70,GAPT,FOXP3,BCL6,HSPD1,MAD2L2 |
| 5.233e-03 | -5.25 | TFAP4 (transcription factor AP-4) | protein interactions | 7023 | 147 | 56 | 19454 | 5460 |
HNRNPL,S100A8,PDE9A,SIN3A,UBP1,TOPBP1,USP15,NR2F6,DNTTIP1,ACTR3B,INO80E,MDC1,PAX6,VRK1,KCTD17,HAPSTR1,EFNB1,PCNA,SMARCB1,RBPJ,TFCP2,SOX2,EXOSC8,MTA3,E2F4,TP53,MAD2L1,MAD2L2,TRAF1,APEX1,HPF1,SRP54,VMAC,ZHX3,MIDEAS,RAN,PARP2,SP1,PKNOX1,CHRAC1,BRCA1,STN1,FBXW11,SMARCE1,ATF1,COIL,GNB4,SKP1,GTF2I,HMGB1,DDX39B,HIRA,BAP1,XRCC5,PRKCA,CTBP1 |
| 5.233e-03 | -5.25 | FARSB (phenylalanyl-tRNA synthetase subunit beta) | protein interactions | 10056 | 147 | 56 | 19454 | 5460 |
RRM1,RAF1,SUPT5H,MAGEB10,CENPM,TP53,MTCH2,GTF2E2,SKA3,GPX7,EZH2,FAF1,CTNNBL1,TOLLIP,FARSA,UBE2A,SAR1B,RPL24,CD274,SWAP70,PHB1,RAC2,RPLP1,CD4,FZR1,KCTD10,SUMO2,HSBP1,ATG16L1,PPP1R8,TPT1,RPA2,FGFR1,HEXIM1,RPLP0,RHOU,BAP1,RPA3,HSPA8,GHRL,USP8,UGP2,MYC,MTPN,BRCA1,RHOB,UBE2H,LMBR1L,CCNF,EIF2AK2,SF3B4,GANAB,PTEN,TENT5C,MAD2L2,ESR2 |
| 5.233e-03 | -5.25 | ADGRE5 (adhesion G protein-coupled receptor E5) | protein interactions | 976 | 147 | 56 | 19454 | 5460 |
YIPF3,SLC29A1,TMEM252,IPO8,MTCH2,SURF4,TMEM87A,CYP2C9,NDUFB5,TMED1,PSEN1,TNFSF8,B4GALT7,UPK1A,HNRNPD,NDUFB8,ADGRE2,P2RY1,RHOG,GLT8D1,LILRB4,RHOH,TNFSF18,CDC42,RND2,TMEM106A,SYNGR2,FUT8,BET1,TM9SF1,FDFT1,GPR35,GOLGA5,ATP2C1,TSPAN15,CLDND1,CERS6,TPST1,LPAR1,CMTM6,ARL6IP6,HBEGF,CUL3,ATP1A3,RHOB,SYNGR1,SERINC1,SLC30A7,SLC1A1,GPR89A,S1PR4,VDAC2,VKORC1L1,B4GAT1,VIRMA,RHOJ |
| 5.254e-03 | -5.25 | USP25 (ubiquitin specific peptidase 25) | protein interactions | 29761 | 93 | 38 | 19454 | 5460 |
MAVS,TNFAIP1,APPBP2,PAX6,RNF41,MT2A,TNKS2,NAP1L3,NEDD8,CNTN1,TRAF2,SUMO1,SYK,RAD23B,HDAC11,HSP90B1,UBE2I,TNKS,PTEN,EIF4A3,UBB,CGAS,SUMO2,TUBB,KCTD10,SUMO3,GAPDH,FEM1B,CDC37L1,CUL3,EDEM1,CUL2,KLHL9,ARMC8,LYZ,CDC73,MYO6,SNRNP70 |
| 5.254e-03 | -5.25 | C19orf25 (chromosome 19 open reading frame 25) | protein interactions | 148223 | 93 | 38 | 19454 | 5460 |
SLC15A1,TFPT,KLHL24,RINT1,SAT1,HSD17B8,STX18,HNRNPH2,P2RY12,USE1,SCLT1,GNB1L,FAM234A,DDIT4L,SEC22B,OTULINL,DNAJC25,ST7,BORCS6,DNAJC1,VTI1B,PNMA3,APLNR,IDE,SEC63,APEX1,S1PR4,PTPN1,HDHD3,NAPA,SSX2IP,SCFD1,PNPO,GPR17,VAMP5,EPS8,INSYN1,CCDC85B |
| 5.254e-03 | -5.25 | UBE2E2 (ubiquitin conjugating enzyme E2 E2) | protein interactions | 7325 | 93 | 38 | 19454 | 5460 |
RNF11,RNF5,RNF115,TRIM37,RING1,RLIM,RNF10,ARRDC3,PCGF2,TRIM3,RNF126,RNF8,ZNRF1,RNF103,NFE2L2,DET1,MDM2,SRPK2,HNRNPL,SIAH1,PGPEP1,TRIM27,TRIM45,STUB1,MARCHF3,COP1,DTL,CBL,USP15,MUL1,TRIM23,RC3H2,BRCA1,RNF14,TRIM32,WWP2,CUL3,UBE2E2 |
| 5.254e-03 | -5.25 | UBR7 (ubiquitin protein ligase E3 component n-recognin 7) | protein interactions | 55148 | 93 | 38 | 19454 | 5460 |
CNDP2,EIF4B,HEXB,PDHA1,VPS33A,RPA2,GNG10,UBR7,EIF3J,HEXA,UBE2W,NAA15,HSPA5,PYGB,H3C1,SEM1,PDHB,NUBP2,DLAT,PDIA6,SEPTIN7,RPA3,TSNAX,SLX1A,PDCD10,H2AC4,RPAIN,PRMT6,CSK,CELA3B,TMPO,EGLN3,THOC1,DYNLL1,ADRM1,AP1G2,PSMB5,ACKR3 |
| 5.276e-03 | -5.24 | ZNF263 (zinc finger protein 263) | protein interactions | 10127 | 144 | 55 | 19454 | 5460 |
XRCC5,DVL2,PPM1G,TWNK,MRPS7,FTL,SAP18,NOTCH2,SUFU,ZSCAN1,ZMYM6,PSPC1,TRAF7,ZMYM2,RBBP4,JAKMIP2,ERH,CBX5,ZNF687,VPS39,NONO,PCBD1,CHTOP,MECP2,COP1,THNSL1,PPP1R12A,FBXO11,MRPS18B,TRIM37,TRIM26,AHCYL1,MSH6,RFC3,CCAR1,RPS27A,FEN1,TOP3B,ZNF397,SPG21,SCAND1,CBX3,EZH2,TOPORS,ILF2,MTA2,SIN3A,TOP1,PLEKHF2,CDC5L,MRPS35,ZNF24,HMGA1,BAZ1B,BRD3 |
| 5.278e-03 | -5.24 | M Phase | REACTOME pathways | R-HSA-68886 | 308 | 118 | 10285 | 3229 |
UBB,SMC4,PPP2R1A,CDC26,PRKCA,PSMD14,RB1,NEK7,H2BC12,PSMD7,CDK1,PSME1,DSN1,H2BC11,PSMB6,PSMA2,TMPO,BUB3,PSMB11,PSMC5,PSMB10,BANF1,SPC24,PSMA4,H2BC17,PSMC4,PSMB5,PSMA3,RAB1A,CDC20,RAB1B,NUP50,H3C1,PSMB1,PSMD3,SKA1,CDC16,CSNK2B,PSMB7,MIS12,NEK9,RAB2A,NUP35,H2BC9,H2BC1,CSNK2A1,SKA2,H2AC14,PSMB9,NUP153,ANAPC2,PSMD6,ANAPC15,CENPM,UBE2D1,PSME2,NUP107,XPO1,MAPRE1,H2AJ,CENPP,H2AX,ARPP19,PSMD12,CCNB1,H2AZ1,ANAPC16,PRKCB,H2AZ2,H2AC7,NUP37,VRK1,LMNA,UBA52,SEC13,RAD21,PAFAH1B1,PSMD10,H2BC14,PSMB3,PPP2R5E,PSMA5,PPP2R5A,BIRC5,LEMD3,NDE1,PSMD4,LMNB1,ANAPC11,PPP1CC,RPS27A,H2AC6,PSMA1,PSMC3,H2AC4,GORASP2,PTTG1,ANAPC4,CENPL,MIR484,NUP62,NUF2,SEM1,CDC23,PSMB4,MAD2L1,MCPH1,PSMA6,PSMB2,PSMD1,NUP42,KIF2A,PPP2CB,PSMC1,NDC80,NCAPG2,H2AB1,B9D2 |
| 5.279e-03 | -5.24 | Cholinergic synapse | KEGG pathways | hsa04725 | 112 | 52 | 7161 | 2463 |
CHRM5,GNG7,GNA11,CREB1,CHRNB2,FOS,GNAO1,GNB4,ADCY3,GNAQ,HRAS,GNG13,CHRM1,PRKACB,ATF4,CHRM3,ADCY2,MAP2K1,GNB1,AKT3,GNG3,PRKCA,GNG12,CHRNA7,GNG10,PIK3CG,CHRM4,KCNJ2,KRAS,GNGT2,GNAI3,PIK3R1,JAK2,PLCB2,AKT1,PIK3R2,GNB3,PLCB1,CREB3L4,KCNQ5,AKT2,GNG11,GNG2,GNAI2,PRKCB,CREB3,CAMK2G,GNG5,PIK3R3,ACHE,PIK3CA,KCNJ3 |
| 5.289e-03 | -5.24 | SDHB (succinate dehydrogenase complex iron sulfur subunit B) | protein interactions | 6390 | 184 | 68 | 19454 | 5460 |
PRDX6,GFM1,RNF113A,DLAT,BAP1,MRPL20,MRPL40,HSCB,EMC1,CDK7,NDUFAB1,MTRES1,PIH1D1,SLC25A3,MMADHC,ACAT1,RTP4,UQCRC2,CCNF,ATP6AP2,VIRMA,ATP5F1B,LDHA,TUFM,TOMM40,CUL2,CUL3,MYC,AUH,MAT2A,NDUFB6,RIT1,UBE2H,STK11,CHCHD4,CISD1,ABCE1,HINT2,SDHC,NDUFA4,PREPL,SDHAF1,HSPD1,IMMP2L,KRAS,TULP3,TOMM7,CARTPT,MTCH2,NDUFA2,NDUFA12,PDHA1,UAP1,GPD2,GATD3,COX4I1,SSBP1,EGLN3,ILVBL,NDUFS8,FZR1,CAND1,COPS5,NDUFV2,LAMTOR2,CLPX,TMEM70,UBXN10 |
| 5.292e-03 | -5.24 | negative regulation of cold-induced thermogenesis | biological process | GO:0120163 | 48 | 23 | 18204 | 5365 |
IL15,ADIPOQ,MAP2K6,RBPJ,PLCL1,WNT10B,NR1H2,TFE3,FLCN,ABHD6,RB1,LGR4,ID1,RHEB,IP6K1,FOXC2,ARRDC3,DDIT3,ACOT13,TLR4,ATF4,NOVA1,STK11 |
| 5.295e-03 | -5.24 | snRNA binding | molecular function | GO:0017069 | 50 | 24 | 18094 | 5411 |
SNRPA,HEXIM1,SNRNP70,PRPF4,SNRPD3,RBM22,HEXIM2,LSM8,DDX39B,SNRPB2,LSM4,PRPF31,COIL,LSM3,RBM7,SNRPA1,RBM41,NCBP2,LSM2,MEPCE,LSM10,ISG20,SART3,CDK9 |
| 5.297e-03 | -5.24 | CTBP2 (C-terminal binding protein 2) | protein interactions | 1488 | 352 | 121 | 19454 | 5460 |
CACNB3,RB1,MDM2,CWC15,FZR1,CSNK2A1,GAPDH,NFKB1,SSX2IP,BRD3,FOXP1,CCR5,DLG1,GLCE,DUSP21,STX11,SOCS2,SMN1,RPL17,THAP1,MVD,FBP1,CARD19,NUPR1,BIRC5,MSRB3,PHAX,CSNK2B,ZBTB18,SGTA,UBE2I,CCNF,STUB1,CTSB,KCNIP3,CACNB2,RUNX1,AR,RPL7A,LCORL,PNPO,HMCES,PRDX6,RPA3,DVL2,MBD3,POLR1H,SIT1,KDM1A,CCNH,CFTR,KLF12,TIMMDC1,UBAP1,ARL15,CARHSP1,KLF4,SDCBP,RPA2,PBDC1,EGLN3,WIF1,IFI27,HNRNPL,NOL4,MMUT,CTNNB1,PRDX1,DYRK1B,STOML2,LST1,CDC23,MKLN1,UBE3A,PLCB1,FHL3,RPS4X,ENKD1,SOX2,MAPK10,TULP3,MTA2,MOXD1,CAAP1,VRTN,ATXN1L,ESR2,RBBP4,PROX1,RPS29,CACNB4,CREBBP,MYC,CUL3,IKZF2,TNFAIP8,DNAJB6,RBBP8,OMG,FBXW11,BIRC2,HSPA8,EP300,SLC35F2,RPS28,NUDT2,FOXP2,MRPS7,STAU1,FUNDC1,YIPF5,TAAR1,LMO4,TCF19,MFAP1,NUFIP2,ZBTB42,KLF3,MED23,CTBP1,FOXS1 |
| 5.315e-03 | -5.24 | SOCS2 (suppressor of cytokine signaling 2) | protein interactions | 8835 | 96 | 39 | 19454 | 5460 |
YES1,SEC61A1,COPS2,EPHA2,SLC7A11,LAMP2,CTNNB1,ELOC,KIT,STK38,BACH1,PSMD12,RIGI,SLC25A10,RAB1A,PPM1G,SLC25A11,GLUL,JAK1,CACUL1,NTRK2,IGF1R,SQSTM1,RTN4,KCTD12,HIKESHI,RNF7,UBAC2,MET,GHR,RPS11,STK16,DCUN1D5,TPD52,SOCS3,MAP1LC3B,DDX39A,TIMM13,SUPT4H1 |
| 5.315e-03 | -5.24 | LMAN2 (lectin, mannose binding 2) | protein interactions | 10960 | 96 | 39 | 19454 | 5460 |
COPS5,GORASP2,MOV10,EMC4,TM9SF4,RB1CC1,RNF128,SEC61B,CCNF,LMBR1L,TOR1B,ESR2,VIRMA,FZR1,YIPF5,ISG15,CFTR,TMEM205,RAF1,UBL4A,CCDC47,SUPT5H,RPA2,NDUFS3,FGFR1,PDIA6,EMC2,RPA3,RAB1A,AKT2,BAP1,PEBP1,TMEM106B,ARF4,FLOT1,EMC1,HSCB,NDUFS2,RER1 |
| 5.315e-03 | -5.24 | DUSP19 (dual specificity phosphatase 19) | protein interactions | 142679 | 96 | 39 | 19454 | 5460 |
MCM6,DUSP19,S100A10,SRM,RAB13,IGF1R,TCEA1,STK26,HSPD1,CCT8,CAPN2,GTPBP1,NME1,PPP2R1A,FEN1,NAA35,TIMMDC1,RAP1A,EPHB6,CCT7,USP5,TMOD3,ACTB,HDDC2,GANAB,CORO1C,GATD3,NAA30,PTK7,ACTA2,COX4I1,PFDN4,EPHA2,BLVRA,CKB,RHEB,MCM4,COX5A,DHPS |
| 5.316e-03 | -5.24 | PJA2 (praja ring finger ubiquitin ligase 2) | protein interactions | 9867 | 141 | 54 | 19454 | 5460 |
DNAJC1,ATP5PD,EGLN3,CDK9,RAB11B,HACD3,SDHB,UBE2N,COX4I1,MAGED2,USP46,KRT8,UBE2D1,PRPF19,PGAM1,YWHAH,XPO1,YWHAG,ATP5F1D,NSMCE3,FAF1,NDUFA4,TTC8,NDUFS3,PRKAG1,DNAJC2,ACADSB,PDHA1,B3GNT2,HADH,FAF2,TULP3,RAB14,TECR,PRRC2A,LMBR1L,UQCRC2,AP2M1,BBS5,SFN,CUL3,RHEB,COX11,NDUFS2,PDHB,UBE2D3,PXMP2,SQSTM1,ATP5PO,ACAA2,NDUFA5,CYC1,UBE2W,CFTR |
| 5.343e-03 | -5.23 | autophagosome membrane | cellular component | GO:0000421 | 54 | 25 | 19108 | 5553 |
ENTPD4,ATG16L1,LAMP2,RAB2A,TEX264,SNAP29,MAP1LC3B,ATP6AP2,RB1CC1,CHMP5,GABARAPL2,TM9SF1,ATG9A,CHMP1A,TMEM74,SH3GLB1,STX17,CHMP2B,CHMP1B,MAP1LC3A,CHMP4C,GABARAPL1,CHMP2A,GABARAP,VMP1 |
| 5.355e-03 | -5.23 | Formation of Incision Complex in GG-NER | REACTOME pathways | R-HSA-5696395 | 43 | 22 | 10285 | 3229 |
CCNH,GTF2H4,UBE2V2,SUMO1,PARP2,UBB,RPA2,GTF2H2,RAD23B,RPS27A,UBA52,GTF2H5,PIAS1,CDK7,RPA3,SUMO3,ERCC3,SUMO2,UBE2N,CETN2,UBE2I,MNAT1 |
| 5.356e-03 | -5.23 | respiratory chain complex IV | cellular component | GO:0045277 | 23 | 13 | 19108 | 5553 |
COX8A,COX7B2,COX5A,COX6A2,UQCRC2,COX4I1,NDUFA4,COX7B,COX4I2,COX6B2,COX6B1,COX7A1,COX6C |
| 5.356e-03 | -5.23 | outer mitochondrial membrane protein complex | cellular component | GO:0098799 | 23 | 13 | 19108 | 5553 |
TOMM40,MTX2,TOMM6,TOMM7,CHCHD6,MFN1,TOMM20,TOMM40L,APOO,TOMM22,CHCHD3,SAMM50,TOMM70 |
| 5.357e-03 | -5.23 | SYF2 (SYF2 pre-mRNA splicing factor) | protein interactions | 25949 | 67 | 29 | 19454 | 5460 |
WDR83,ATG16L1,SNRPN,ESS2,SNRPE,SNIP1,SNRPA,NKAPD1,CWF19L1,CDC40,TSSC4,RBM22,SNRPG,PRPF19,MYC,ZCCHC10,HNRNPC,MCM3,TRA2A,SNRPB,POU5F1,ELAVL2,ARMC7,GCFC2,SNRNP40,BUD31,SNRPA1,CWC15,CDC5L |
| 5.357e-03 | -5.23 | ID1 (inhibitor of DNA binding 1) | protein interactions | 3397 | 67 | 29 | 19454 | 5460 |
SQSTM1,PIAS1,USP8,TRIM63,B4GALT7,SGF29,STXBP1,ELK4,TP53,TXNL4A,CASK,USP39,HEXIM2,SMAD3,CAV1,ELK1,CDC20,MPP1,BUD31,FZR1,PSMD4,ELOC,SUV39H1,MYC,IFI16,THOC6,USP15,PSMD14,TRAF6 |
| 5.357e-03 | -5.23 | GBE1 (1,4-alpha-glucan branching enzyme 1) | protein interactions | 2632 | 67 | 29 | 19454 | 5460 |
PRMT6,CSK,CAP2,AR,XPO1,SMAD4,OAZ1,GYS1,DNM2,RB1,MIF,UMPS,PYGM,ACO1,TRMT1L,RAF1,STBD1,SOX2,DDX39A,OTUD6B,MAP1LC3B,EZH2,RPA2,NLE1,RPA3,MMP9,SETD4,AP1M1,PYGB |
| 5.357e-03 | -5.23 | NECAP1 (NECAP endocytosis associated 1) | protein interactions | 25977 | 67 | 29 | 19454 | 5460 |
MCM4,DNAJC5,ARHGAP21,BAZ1B,SMARCA5,H2AC14,AP2A1,H1-10,LCMT1,MACROH2A1,AP2M1,H2AZ1,DAPK1,H1-3,NECAP2,KHDC4,MACROH2A2,AP2S1,PITPNA,CARHSP1,APOBEC3C,CBX3,TOP2B,DVL2,TMUB1,MDC1,AP1M1,RPS27A,STAU1 |
| 5.357e-03 | -5.23 | KYNU (kynureninase) | protein interactions | 8942 | 67 | 29 | 19454 | 5460 |
CSE1L,ETFA,MYOZ3,COIL,PALM2AKAP2,PPM1G,LDHAL6B,ADSS2,CNDP2,SPR,MVD,LMO4,CDC42,LDHA,BCCIP,GLRX,PPIA,ACTA2,SSU72,SGTA,DSTN,AGR2,ADK,CCT2,CHORDC1,AGPAT1,MCCD1,TPM3,CFL1 |
| 5.357e-03 | -5.23 | EVA1B (eva-1 homolog B) | protein interactions | 55194 | 67 | 29 | 19454 | 5460 |
RETSAT,CNTNAP1,DHRS7,NRP1,AREL1,C2CD2L,SRPRA,SMAD3,SDC4,TRIM27,SGTA,SLMAP,ACP2,NUP35,DCAKD,NECAP2,SDC2,CA14,GHITM,PTRH2,GNB1L,CYB5B,LEMD3,C1QL1,DDR1,EFNB1,SLC25A51,SACM1L,SLC37A4 |
| 5.366e-03 | -5.23 | EXOC2 (exocyst complex component 2) | protein interactions | 55770 | 99 | 40 | 19454 | 5460 |
P2RY10,EXOC5,DDRGK1,EXOC1,RALB,MOV10,MYC,CUL3,RAB11A,GPR17,EXOC8,SMAD4,RHOB,H2AC4,BECN1,YWHAZ,SCN2B,APLNR,VIRMA,ESR2,CDC5L,RALA,LPAR6,PGM1,PTAR1,TBK1,COMTD1,KBTBD4,CHRM3,IL1R2,HECTD1,RPA2,EXOC3,SDC2,DHX9,DLAT,RPA3,CXCR4,AATF,NPTN |
| 5.366e-03 | -5.23 | STK25 (serine/threonine kinase 25) | protein interactions | 10494 | 99 | 40 | 19454 | 5460 |
LIN7C,CTTNBP2,SIKE1,ANAPC16,STK26,MTDH,UBE2D3,HSCB,TOLLIP,ZDHHC17,MTMR6,ANGPT1,PPP2R1A,CHMP4C,PPP4C,ACACA,RPL12,PPP2CB,EIF4A3,TRIM27,CAB39,MOB4,TRIM45,PRNP,DYNLL1,TAX1BP1,TCP1,CTTNBP2NL,SLMAP,MAD2L1,STK3,HSP90AB1,FGFR1OP2,GNG2,CEP70,STK24,YWHAZ,PDCD10,HSP90AA1,YWHAB |
| 5.366e-03 | -5.23 | INTS11 (integrator complex subunit 11) | protein interactions | 54973 | 99 | 40 | 19454 | 5460 |
SOX2,PPP2R1A,PLSCR4,SUPT5H,RAF1,TOP3B,ANXA7,VAC14,THBS3,BAG2,FAM222B,PLSCR1,SSRP1,TFG,RIGI,IMMP2L,STAU1,LASP1,SEM1,KRAS,COMMD5,USP2,CUL3,ENY2,MDFI,MYC,RIT1,KPNA1,POLR2F,RPLP1,CSNK2B,INTS10,NABP1,PPP2CB,CCNF,ESR2,APEX1,POLR2B,POLR2I,RPL35A |
| 5.366e-03 | -5.23 | ARPC5 (actin related protein 2/3 complex subunit 5) | protein interactions | 10092 | 99 | 40 | 19454 | 5460 |
ATG16L1,CFTR,CDC42,ACTN4,SOX2,ARPC3,CAPZA2,ACTR2,TCP11L1,PPARG,NUPR1,EIF4B,BAP1,RPA3,ARPC2,STK26,ABCE1,RBCK1,OXCT1,ANP32B,RAD21,POLA2,CALR,MYC,BTF3L4,ACTR3B,HDAC6,BICD2,MAPRE1,VMP1,BRD3,CTTN,TAX1BP1,HNRNPL,SPPL3,DAPK1,ESR2,TOM1L1,UBB,SH3BGRL |
| 5.367e-03 | -5.23 | PRKD1 (protein kinase D1) | protein interactions | 5587 | 181 | 67 | 19454 | 5460 |
EFHD2,BAD,GTF2F1,YES1,TXNDC12,PRKCE,LAMTOR3,MGST3,SRC,GNB1,GNAI2,MAT2B,COX6B1,COPS7A,AR,NONO,YWHAZ,IVNS1ABP,SORD,HSP90AA1,PRKD3,SNX33,HDAC5,RPL4,SRSF2,FXR2,HSCB,MT2A,TOMM22,SYK,COX6C,CSNK1A1L,CSNK1A1,MRTO4,COX4I1,ALDH1A3,COPS2,ATP6V1A,CCAR2,TRIR,PRNP,HNRNPL,CRIP1,TPM3,APOBEC3F,YWHAG,COPS5,YWHAH,PPM1B,HSPB1,USP15,HNRNPA2B1,ZYX,IGF1R,PRPSAP1,MYO1B,G3BP1,AKAP12,HNRNPDL,PRPS1,MEPCE,TP53,CMPK1,JUN,DISC1,RPL18,EIF1AX |
| 5.367e-03 | -5.23 | DMAP1 (DNA methyltransferase 1 associated protein 1) | protein interactions | 55929 | 181 | 67 | 19454 | 5460 |
BRD3,HSPB1,GAS8,ACTL6B,CSNK2A1,EIF2B5,ARL6IP5,MEAF6,H2AZ1,CETN3,TSG101,H2BC1,EZH2,GINS4,TPD52,ANP32A,ZNHIT1,MAX,ING1,SOX2,H2AX,RUVBL1,TOLLIP,H3C1,H1-6,KRAS,MNAT1,UTP25,ANP32B,PFDN1,CDCA7L,BCL7B,KLHL15,RGS6,RUVBL2,TRIM21,PCNA,CPNE2,LMNB1,RIT1,NLRP3,CSGALNACT1,H1-1,CCHCR1,EXOC8,MORF4L1,MYC,AR,TRIM29,ACTB,ESR2,SRC,BTG3,MAD2L1,VPS72,MACROH2A1,SRP54,RTF2,PLAC1,KLC2,ING5,ACTL6A,ZNF428,KLF12,FTL,CFDP1,DR1 |
| 5.369e-03 | -5.23 | macromolecule methylation | biological process | GO:0043414 | 129 | 52 | 18204 | 5365 |
METTL18,SNRPD1,NTMT1,SETD4,RAMAC,METTL2A,TRMT6,TRMT10B,FAM98A,SNRPG,RBM15B,TRMT61A,VCPKMT,FTSJ3,SNRPD2,SLC25A26,WDR6,BUD23,MEPCE,PRMT6,TRMO,METTL21A,SETD3,SNRPE,METTL25B,EEF2KMT,TFB1M,PRMT2,RAB6A,EMG1,CSKMT,TYW3,SNRPB,SETD7,TRMT11,METTL6,PRMT5,METTL15,ETFBKMT,HSD17B10,TRMT1L,LCMT1,TRMT13,SNRPD3,HENMT1,METTL22,FTSJ1,MRM2,ETF1,TRMT112,EEF1AKMT3,TRMT5 |
| 5.379e-03 | -5.23 | SH3KBP1 (SH3 domain containing kinase binding protein 1) | protein interactions | 30011 | 304 | 106 | 19454 | 5460 |
FGFR1,WTAP,MET,SH3GLB2,CD2AP,SGF29,HSPA5,GRPEL1,SEPTIN6,INPPL1,DVL2,RNF34,IVNS1ABP,ANAPC4,PTPN11,CDC16,RACGAP1,ATP5F1A,GPRASP3,CHMP5,RPGRIP1L,CTSB,IRF2BP1,TRAF1,VIRMA,SRC,UBB,SH3BGRL,ENO1,UBE2I,CSNK2B,CAPZA2,PIK3CA,SPRY1,SH3GLB1,TGFBR2,WASL,HNRNPK,AKAP12,MDC1,CAPZA1,FBXO25,SLC25A11,SEPTIN7,MAP4,FGR,BMPR1B,MOV10,DAG1,CSNK2A1,PRNP,KCTD3,CD2,SLAIN2,EPHB6,TMPO,ALDH1A3,HRAS,FRS3,PAK2,SLC25A3,CSNK1A1,PSRC1,KLC2,ZC3H14,MRPL12,STAP1,RAB5A,PSMA3,HSPA8,BIRC2,RPS6KA4,SERPINH1,PAPOLA,HNRNPC,RAB11A,MYC,UFD1,PRRC2A,MIDEAS,ZMAT2,CHMP4C,CRKL,HGS,MTA2,PNMA5,RAF1,TRAF2,KIT,PABPC1,PDIA6,SRSF7,HSPB1,PPP3CA,VPS4A,CBL,CDC23,PIK3R1,PPFIBP1,KCTD10,CHMP2A,SRSF10,SRSF1,DNM2,CYGB,TSG101 |
| 5.386e-03 | -5.22 | HDAC7 (histone deacetylase 7) | protein interactions | 51564 | 135 | 52 | 19454 | 5460 |
CCAR2,KCTD3,RAC2,EIF4E2,SIN3A,YWHAB,CTNNB1,YWHAG,YWHAH,MOV10,GNMT,ZBTB16,AKAP12,HINT1,TESK2,PPP1R12A,MEF2C,ACTN4,TOP3B,LDB2,UBE2I,FOXP3,EDNRA,RRAS2,GNG12,RIT1,YWHAZ,PPP1R16A,NR2E1,AR,SFN,BCL6,UGP2,MEF2A,MIEN1,FBXW7,NME4,HDAC3,EP300,HDAC5,RTKN,FLYWCH2,PML,KLF4,ADNP,ZMYM6,CDC42,SIPA1L1,PPP1CB,UBL3,DDIT4L,INPP5E |
| 5.386e-03 | -5.22 | EML4 (EMAP like 4) | protein interactions | 27436 | 135 | 52 | 19454 | 5460 |
TRIM36,LUC7L3,RPA2,NEK7,ATG16L1,SKP1,SMC4,STAU1,KDM1A,MIA2,HSPA8,RPA3,MAPRE1,ILK,FBXW11,CFL1,HNRNPC,SMARCA5,MYC,TFEB,VIRMA,DYNLL1,TUBB,RBBP4,MACROH2A1,PRMT5,TUBA1B,ZNF174,MTA2,TUBB4B,KIF2A,ACTR1A,TP53,RAF1,PRPS1,KPNA2,RUVBL1,RBBP7,BAG2,RUVBL2,BHLHE40,PPP1R12A,NEK9,MAP1B,USP15,SNRNP70,DDRGK1,INSYN1,KXD1,CDK9,C1QTNF1,ARL4D |
| 5.403e-03 | -5.22 | RAF/MAP kinase cascade | REACTOME pathways | R-HSA-5673001 | 245 | 96 | 10285 | 3229 |
IL2RG,YWHAB,DUSP6,PPP2R5A,FGF1,MET,PAQR3,FGF23,PSMA5,SPTAN1,PPP2R5E,PSMB3,PEBP1,PSMD10,FRS3,SRC,DUSP9,FGF10,RAP1B,MAP2K1,KRAS,UBA52,FGF22,WDR83,RAF1,FGF16,IL2RB,LAMTOR3,CAMK2G,VWF,PSMC1,CUL3,HRAS,KIT,PPP2CB,LAMTOR2,IL5,PSMB2,PSMD1,PSMA6,PEA15,RASGRP3,SHC1,PSMB4,SEM1,DUSP1,PSMC3,PSMA1,IL3,RPS27A,SPRED1,PHB1,PSMD4,PSMD3,JAK2,PSMB7,PSMB1,PSMB5,PSMA3,PSMC4,PSMA4,FGFR1,IL2,PSMC5,PSMB11,PSMB10,PSMA2,PSMB6,DLG4,BRAP,CSK,SPTBN1,PPP5C,ANGPT1,PSME1,PSMD7,FGF17,PSMD14,UBB,PPP2R1A,CSF2,FGF7,JAK1,PSMD12,SHC3,RAP1A,FGF3,PSME2,PSMD6,HBEGF,PSMB9,SPRED2,IL2RA,MAP3K11,NEFL,DUSP10 |
| 5.403e-03 | -5.22 | SOS-mediated signalling | REACTOME pathways | R-HSA-112412 | 245 | 96 | 10285 | 3229 |
PSMD3,PSMB7,JAK2,PSMB1,PSMB5,PSMA3,PSMC4,PSMA4,PSMB11,FGFR1,PSMC5,IL2,PSMB10,PSMB6,PSMA2,DLG4,CSK,BRAP,SPTBN1,PPP5C,PSME1,ANGPT1,PSMD7,FGF17,PSMD14,UBB,PPP2R1A,CSF2,JAK1,FGF7,PSMD12,SHC3,RAP1A,FGF3,PSME2,PSMD6,HBEGF,PSMB9,SPRED2,IL2RA,MAP3K11,DUSP10,NEFL,IL2RG,YWHAB,DUSP6,FGF1,PPP2R5A,MET,PAQR3,FGF23,PSMA5,SPTAN1,PPP2R5E,PEBP1,PSMB3,FRS3,PSMD10,SRC,DUSP9,FGF10,RAP1B,MAP2K1,KRAS,FGF22,UBA52,WDR83,RAF1,FGF16,IL2RB,LAMTOR3,CAMK2G,VWF,CUL3,PSMC1,LAMTOR2,PPP2CB,KIT,HRAS,IL5,PSMB2,PSMD1,PEA15,PSMA6,SHC1,RASGRP3,PSMB4,SEM1,DUSP1,PSMC3,PSMA1,RPS27A,IL3,PHB1,PSMD4,SPRED1 |
| 5.403e-03 | -5.22 | SHC1 events in EGFR signaling | REACTOME pathways | R-HSA-180336 | 245 | 96 | 10285 | 3229 |
VWF,CUL3,PSMC1,FGF16,CAMK2G,LAMTOR3,IL2RB,PSMD1,PSMB2,PSMA6,PEA15,IL5,HRAS,KIT,LAMTOR2,PPP2CB,SEM1,DUSP1,RASGRP3,SHC1,PSMB4,IL3,RPS27A,SPRED1,PSMD4,PHB1,PSMC3,PSMA1,YWHAB,PPP2R5A,FGF1,DUSP6,IL2RG,PPP2R5E,SPTAN1,PSMB3,PEBP1,PAQR3,MET,PSMA5,FGF23,FGF10,PSMD10,FRS3,DUSP9,SRC,WDR83,UBA52,FGF22,RAF1,RAP1B,KRAS,MAP2K1,FGF7,JAK1,PSMD12,CSF2,SHC3,RAP1A,IL2RA,SPRED2,PSMB9,PSME2,FGF3,HBEGF,PSMD6,NEFL,DUSP10,MAP3K11,PSMB5,PSMA3,PSMC4,PSMB7,JAK2,PSMD3,PSMB1,PSMA2,PSMB6,BRAP,CSK,DLG4,PSMA4,PSMB10,IL2,PSMC5,FGFR1,PSMB11,FGF17,PSMD7,PPP5C,SPTBN1,ANGPT1,PSME1,PPP2R1A,UBB,PSMD14 |
| 5.403e-03 | -5.22 | GRB2 events in EGFR signaling | REACTOME pathways | R-HSA-179812 | 245 | 96 | 10285 | 3229 |
IL5,HRAS,LAMTOR2,PPP2CB,KIT,PEA15,PSMA6,PSMB2,PSMD1,LAMTOR3,CAMK2G,IL2RB,FGF16,CUL3,PSMC1,VWF,PSMA1,PSMC3,SPRED1,PSMD4,PHB1,IL3,RPS27A,PSMB4,SHC1,RASGRP3,DUSP1,SEM1,PSMA5,FGF23,PAQR3,MET,PSMB3,PEBP1,PPP2R5E,SPTAN1,IL2RG,PPP2R5A,FGF1,DUSP6,YWHAB,KRAS,MAP2K1,RAP1B,RAF1,WDR83,UBA52,FGF22,DUSP9,SRC,PSMD10,FRS3,FGF10,RAP1A,SHC3,CSF2,PSMD12,FGF7,JAK1,MAP3K11,NEFL,DUSP10,HBEGF,PSMD6,PSME2,FGF3,IL2RA,SPRED2,PSMB9,PSMB10,IL2,PSMC5,FGFR1,PSMB11,PSMA4,BRAP,CSK,DLG4,PSMB6,PSMA2,PSMB1,JAK2,PSMB7,PSMD3,PSMC4,PSMB5,PSMA3,PSMD14,PPP2R1A,UBB,ANGPT1,PSME1,PPP5C,SPTBN1,FGF17,PSMD7 |
| 5.408e-03 | -5.22 | TMPRSS13 (transmembrane serine protease 13) | protein interactions | 84000 | 102 | 41 | 19454 | 5460 |
TOR3A,GINM1,FUT8,GPC4,IL6ST,FKBP14,SIGMAR1,ADAMTS1,CPE,LRP10,TIMP3,GLCE,UFL1,EMC1,B4GALT7,GALNT2,GLT8D2,SKAP2,DAG1,SPON1,ARL2BP,CDK5RAP3,PSMD14,BPNT2,C1GALT1C1,FAM177A1,NECTIN2,B4GALT1,LRP12,OAF,EXT1,LDLR,CETN3,ALCAM,DNAJB9,COCH,MGAT1,B4GALT4,EXTL2,LMAN1,EFNA5 |
| 5.408e-03 | -5.22 | POLE3 (DNA polymerase epsilon 3, accessory subunit) | protein interactions | 54107 | 102 | 41 | 19454 | 5460 |
CHMP1A,EZH2,PSMB7,APEH,TRAPPC13,GNB1L,RAP1A,B3GNT2,NUCKS1,SSRP1,POLE4,POLA2,XRCC5,POLD2,TOP2B,BAP1,PRIM2,SCYL2,DR1,STK26,PCNA,HAPSTR1,TRAPPC2L,CHRAC1,PPM1B,SMARCA5,RAB2A,HMGA1,MOV10,CPSF2,SLC30A5,DRAP1,TOP1,DNAJC1,HSP90AB1,EGLN3,PPP2CB,ENO1,ARF1,LDLR,EED |
| 5.408e-03 | -5.22 | FNTB (farnesyltransferase, CAAX box, subunit beta) | protein interactions | 2342 | 102 | 41 | 19454 | 5460 |
KRAS,YKT6,CAMKV,CHCHD2,PITHD1,RPL17,BAP1,RPA3,ATPAF2,FAM53C,RPL23A,MRPS11,RAP2A,SNX33,PTP4A2,PGGT1B,CCR1,CAPN2,RPL18,DUSP14,RPL27A,TOP3B,ARFGAP1,CAPN1,PAFAH1B1,AURKAIP1,TP53TG5,PRNP,PTP4A3,UBB,DYRK1A,RPL10,CWC15,RPRD1A,HRAS,ACTA2,RRAS2,SMPD2,PPM1B,SMG9,HDAC6 |
| 5.408e-03 | -5.22 | LNX2 (ligand of numb-protein X 2) | protein interactions | 222484 | 102 | 41 | 19454 | 5460 |
PEG10,EAF2,VIRMA,TRAF1,ATP5F1B,TAB1,TUBB,UBE2I,OPTN,INMT,SCNM1,UBE2H,NTAQ1,DRAP1,PIK3R1,SFN,PIK3R3,RBM17,USP2,PHYKPL,FANCG,TIFA,FHL3,RLIM,PPIH,SHISA2,MRFAP1L1,GADD45A,CDKN2C,PRKCA,SH3GLB2,SMARCB1,GRAP2,MSRB3,RPA2,RAB6B,ZNF581,TRAF2,LNX2,MYLIP,CDK4 |
| 5.415e-03 | -5.22 | SPECC1 (sperm antigen with calponin homology and coiled-coil domains 1) | protein interactions | 92521 | 132 | 51 | 19454 | 5460 |
GJA1,RAC2,RAB35,HRAS,DIRAS3,CAV1,RHOH,LAMP3,YWHAH,YWHAG,CTNNB1,DDRGK1,LAMP2,POU5F1,YWHAB,RHOG,KRAS,TRAF2,NUPR1,MOB3C,VPS33A,ACTR2,CAPZA2,TMEM74,CTTN,VIRMA,ESR2,ATP6AP2,RHOJ,BTF3,PPP1CC,MYC,SFN,RAB11A,UBE2H,MAPRE1,VMP1,LAMTOR1,RHOB,YWHAZ,RAB5A,RAB9A,DDX39B,RHOU,STX7,PPP1CB,CDC42,CFTR,NUP62,ATG16L1,TRIM36 |
| 5.416e-03 | -5.22 | regulation of ubiquitin-dependent protein catabolic process | biological process | GO:2000058 | 170 | 66 | 18204 | 5365 |
SOCS4,GABARAP,FBXW7,RPS7,TRAF7,CCAR2,GCLC,CLU,STUB1,AKT1,BAG2,HFE,NOP53,SUMO2,RCHY1,USP38,ZER1,CSNK1E,TAF9,FZR1,FHIT,CDC20,CAMLG,DDRGK1,MDM2,XPO1,ZFAND2A,UBE2K,UBE3A,DESI1,UFL1,PIAS1,TRIB1,DNAJB2,CSNK1A1,CCDC22,MTM1,SGTA,RPL23,PSEN1,HECTD1,COP1,CSNK2A1,SOCS5,SMURF1,TMEM168,SUFU,RAD23B,CDK5RAP3,HSP90AB1,GSK3A,FBXO22,SUMO1,CAV3,USP5,DET1,PSMD10,RNF139,PRMT6,NFE2L2,PTEN,USP14,DISC1,TGFB1I1,PML,WNT10B |
| 5.440e-03 | -5.21 | ZMAT2 (zinc finger matrin-type 2) | protein interactions | 153527 | 105 | 42 | 19454 | 5460 |
ZNF330,METAP1,CCDC71,TOP1,KCTD9,SNRPB,MYC,UBE2H,LSM3,NAB2,SSX2IP,MED4,BICD2,LSM6,NUP50,TCEA1,PICK1,RPL31,SNRPA,SSRP1,ABHD10,COIL,MRPS18C,STAU1,ZBTB14,ASF1A,TRIM37,H3C1,FXR2,LSM4,TRAF2,TP53,ERRFI1,SF3A1,ATP5PB,TRIM36,CDR2,TFIP11,LSM2,LMNA,EZH2,CBX3 |
| 5.440e-03 | -5.21 | MED9 (mediator complex subunit 9) | protein interactions | 55090 | 105 | 42 | 19454 | 5460 |
MAX,RPAP2,MED30,SMAD1,CD59,MED23,CDK8,POLR2G,POLR2C,POLR2D,MED31,RPA3,STX8,SNAPC1,HSPA8,MED13L,CTNNBL1,MED11,TRA2B,FBXW7,RUVBL1,NRGN,RPS27A,MED22,CTNNB1,MED27,MED10,MED21,MED29,STN1,SMAD2,MED4,RPL8,GTF2B,METAP2,POLR2F,TMOD3,MED17,POLR2I,POLR2B,GNAI2,GNB1 |
| 5.440e-03 | -5.21 | EIF4H (eukaryotic translation initiation factor 4H) | protein interactions | 7458 | 105 | 42 | 19454 | 5460 |
PSPC1,SYNCRIP,LCMT1,RPS20,GSK3A,PRNP,HNRNPL,G6PD,SEC63,MAT2B,LDHB,MYC,MOV10,ATP1B1,BTF3,MRPL9,BICD2,MAPRE1,SERPINB1,AHSA1,BAP1,RPA3,EWSR1,PICK1,DNAJB4,PAFAH1B2,STAU1,KGD4,G3BP1,HNRNPA0,TRA2B,TRIM26,SAR1B,HNRNPDL,EIF4E,DLG3,DDIT4L,RBMS2,SPG21,EEF2,GDI2,RPA2 |
| 5.440e-03 | -5.21 | EPS8 (EGFR pathway substrate 8, signaling adaptor) | protein interactions | 2059 | 105 | 42 | 19454 | 5460 |
NRP1,CBL,NTRK3,SHC1,BICD2,RHOB,SPOP,CCDC85B,SMARCE1,TYW3,HNRNPC,EPS8,SRC,ESR2,ACTB,PRNP,RFXAP,CSNK2B,ARMC1,HRAS,CASK,SERPINA5,NUPR1,ITGB5,NACC2,BORCS6,CFTR,MAP1LC3B,MND1,SOX2,TANK,USP6NL,MARCKSL1,MRPL20,RIGI,MDC1,PDE2A,ETFA,OIP5,KRAS,BCKDK,MAP3K11 |
| 5.440e-03 | -5.21 | GPATCH8 (G-patch domain containing 8) | protein interactions | 23131 | 105 | 42 | 19454 | 5460 |
HNRNPD,RIT1,UBE2H,DDX23,SNRNP70,H2BC9,MYC,EGLN3,NUP35,VIRMA,ESR2,SRPK2,SNRNP40,SNRPA1,SUMO2,SYT2,OLFM2,GATAD1,TIMM8B,PHF12,CPSF1,ATXN1L,EIF4A3,ZNF330,LACC1,NFKBIL1,TMEM165,CD2BP2,TIMM13,H2AX,RBFOX2,ATG16L1,JPH4,TP53,SRSF4,SAP18,CAMKV,APH1A,EWSR1,DVL2,SNIP1,RPA3 |
| 5.440e-03 | -5.21 | ZNF148 (zinc finger protein 148) | protein interactions | 7707 | 129 | 50 | 19454 | 5460 |
LNX2,KLF12,CDKN1A,KLF3,LMNA,PML,TRIM10,EP300,NUP50,JADE1,CLK1,HDAC3,FOXP2,COIL,CUL3,MYC,CEP70,GORASP2,AR,BRCA1,SP1,ELK3,ZNF330,CPSF1,PNMA1,PHAX,SIAH1,ESR2,VIRMA,RABIF,APEX1,TP53,ELF1,SOX2,EGR2,EZH2,CBX3,HAPSTR1,NOC4L,PAX6,FOXP4,MDC1,RIGI,PFDN5,IFI16,PDIA3,BRD3,FOXP1,KPNA1,KLF9 |
| 5.440e-03 | -5.21 | NCBP2 (nuclear cap binding protein subunit 2) | protein interactions | 22916 | 129 | 50 | 19454 | 5460 |
EZH2,DCUN1D5,RAF1,SUPT5H,E2F4,SOX2,HNRNPF,KPNA2,RNF20,POLDIP3,SSRP1,RBM3,SNRNP70,KPNA1,WWP2,XPO1,FZR1,CAND1,TOP1,RBM42,NCBP2,SYNCRIP,PHB1,DYRK2,ATG16L1,SF3A1,CFTR,FBXW7,EIF4E,AATF,SNRPA,DDX39B,PNO1,NUP50,ATG3,RC3H2,RBM7,RIT1,MYC,RAB11A,RNF40,KPNA6,SNRPB,POLR2B,RPL10,ESR2,SRPK2,EIF4A3,RAN,PHAX |
| 5.444e-03 | -5.21 | ERBB4 (erb-b2 receptor tyrosine kinase 4) | protein interactions | 2066 | 178 | 66 | 19454 | 5460 |
GRB10,PTPN11,PIK3R3,CFL1,SOCS5,HBEGF,S100A11,HSP90AA1,SLA2,DLG4,TMA7,STAT5A,TXN,TAB1,TVP23B,YES1,SRC,DUSP10,MTMR6,DUSP14,DUSP18,SYK,HSH2D,GABARAPL2,VAV2,GRM2,WWP1,FKBP1A,INPPL1,RTN4,USP8,PIK3R2,STAP1,RNF41,PIK3R1,SNAP91,XPO1,HDAC6,SHC3,FAM241B,SHC1,PPM1B,NCK1,CBL,FGR,ITK,DUSP6,TMEM14A,SH2D1A,GJA1,MDM2,LCP2,DLG3,TP53,SELENOK,SOCS3,MTMR2,GRAP2,TAB2,DLG1,ERG28,NTRK2,HSPE1,SOCS2,DUSP21,DUSP19 |
| 5.444e-03 | -5.21 | FIS1 (fission, mitochondrial 1) | protein interactions | 51024 | 206 | 75 | 19454 | 5460 |
LEMD3,TBC1D17,PDCL,VIPAS39,SAMM50,ARMCX3,VAPB,PLAA,ARHGAP1,SEC22B,MTX2,TMEM209,FBXL4,ARMCX2,ATAD1,EMC1,HSCB,YKT6,SQSTM1,TTC1,MAVS,AKAP1,EXD2,JAGN1,FIS1,CISD1,CFL1,TOMM40,SCN3B,CUL3,C9orf72,CREB3,ATP6AP2,RNASEK,ESR2,UBB,SPCS1,RAB14,ATP5F1B,RANBP6,RMDN3,FAM91A1,VAMP3,OPTN,DCUN1D5,TMEM14B,CYB5B,SLC25A20,AQP3,STIM1,GPAM,FAF2,ABHD6,CCDC47,MIEF1,TBK1,STBD1,RAB18,FKBP8,APH1A,USP30,EMC2,NDUFA4,ATP5PF,PEX3,ESYT1,SLC2A1,DDRGK1,SLC25A46,MARCHF5,TOMM70,LMAN1,CDCA3,EHBP1,PTPN1 |
| 5.453e-03 | -5.21 | IL23-mediated signaling events | Pathway Interaction DB | il23pathway | 37 | 21 | 2226 | 782 |
IL12B,IL1B,IL17F,IL23A,IFNG,IL2,CXCL9,NFKBIA,SOCS3,IL6,IL18,CCL2,PIK3CA,CXCL1,STAT5A,TNF,PIK3R1,JAK2,NFKB1,STAT1,CD4 |
| 5.454e-03 | -5.21 | TCEAL4 (transcription elongation factor A like 4) | protein interactions | 79921 | 42 | 20 | 19454 | 5460 |
RB1CC1,UBE2H,HSPB1,USP15,HECTD1,IFRD1,CNDP2,SLC35F6,TP53,PPP2R1A,TCEAL1,MIF,TAX1BP1,HNRNPK,TRIM63,EGLN3,USP5,DVL2,PSME1,TRIM27 |
| 5.454e-03 | -5.21 | MARCHF3 (membrane associated ring-CH-type finger 3) | protein interactions | 115123 | 42 | 20 | 19454 | 5460 |
CHPF2,UBE2M,ENDOD1,TFRC,FATE1,NCSTN,UBE2E2,WWP2,NOTCH2,UBE2W,VAMP7,AASDHPPT,ATAD1,UBE2D3,NDUFS2,UBE2K,BAG2,SLC39A10,TYMS,TMX2 |
| 5.454e-03 | -5.21 | VAMP1 (vesicle associated membrane protein 1) | protein interactions | 6843 | 42 | 20 | 19454 | 5460 |
FCER1G,VAPB,LMNA,TMEM14B,STX1A,SCN3B,TMEM101,SNAP29,DNAJC5,DDX39A,REEP4,SGMS2,APEX1,CRB3,ELOVL7,CYB5R3,ELOVL4,TMX2,SNAP23,RETREG3 |
| 5.461e-03 | -5.21 | INSIG1 (insulin induced gene 1) | protein interactions | 3638 | 126 | 49 | 19454 | 5460 |
PGRMC1,VAPB,MYL6,HSPA8,HNRNPAB,CCT2,H2AZ2,ATP1A1,VDAC2,CTNNA1,PRMT5,RPS12,SEC61B,ACAP2,CSNK1E,RANBP1,TP53,INSIG2,MTCH2,ACTN4,FAF2,EEF1A1,ERLIN2,EEF2,TUBB4B,TFRC,PSMC3,FSTL1,HSPD1,HNRNPA2B1,LSM14A,TRIM21,RUVBL2,HNRNPK,PDIA3,PRDX1,HNRNPA1,TPM3,POR,CDH13,RNF139,RPL12,LDLR,KRT8,CAND1,ERLIN1,PPIA,HSP90AB1,TMEM237 |
| 5.461e-03 | -5.21 | HRNR (hornerin) | protein interactions | 388697 | 126 | 49 | 19454 | 5460 |
TRIM6,TP53,FBP1,RAF1,RNF8,PPME1,PDHA1,EWSR1,FAF1,MEPCE,TRIM37,VDAC1,HNRNPA1,COPS5,HDAC6,DIRAS2,CSTA,ARL4D,ARL10,EFNA3,FABP5,MDM2,CFTR,WTAP,HEXIM1,METTL14,GRM2,CDK1,JUP,SOD1,DDX39B,RNF11,AR,USP14,BTF3,GSTK1,CUL2,CDKN3,MYC,UBE2H,HSP90AA1,YWHAZ,TXNIP,TRIM23,CCNF,ARF1,DYRK1A,LGALS3,NDN |
| 5.464e-03 | -5.21 | DRD2 (dopamine receptor D2) | protein interactions | 1813 | 108 | 43 | 19454 | 5460 |
CLDND1,TSPAN7,CERS2,GABBR1,APH1A,TF,LPAR1,PRKCB,HRH3,SLC6A3,RTN4,BCAP29,GRIA2,CRELD1,TSPAN3,GNAZ,GNAI3,GHITM,TRAM1,YIPF3,ZDHHC4,SYNGR2,TMEM101,GPR37,MDM2,KBTBD6,SERINC3,GNAI2,CAV1,KCNJ3,NDFIP1,WDR45,ADGRG1,GPR137,VDAC2,DNM2,SLC6A1,TRPC1,SPP1,TMEM11,ARL6IP6,SLC22A17,OPRM1 |
| 5.464e-03 | -5.21 | HPRT1 (hypoxanthine phosphoribosyltransferase 1) | protein interactions | 3251 | 108 | 43 | 19454 | 5460 |
ISCU,SDCBP,RPA2,PIH1D1,HEXIM1,ELOVL1,UBE2M,RPA3,BAP1,STAU1,EIF1B,CUL3,MYC,USP14,ATP5F1A,NTAQ1,BRCA1,RHOB,UBE2H,CCNF,PPAT,TENT5C,RAB14,SPG21,SOX2,MAP1LC3B,PPID,SREK1IP1,HSD17B10,EWSR1,GNMT,PTGES3,SAR1B,DDRGK1,AGR2,UBE2N,PHB1,EEF2KMT,MTAP,RAC2,MIF,GLRX,EGLN3 |
| 5.464e-03 | -5.21 | CLASP1 (cytoplasmic linker associated protein 1) | protein interactions | 23332 | 108 | 43 | 19454 | 5460 |
KRT8,SRP14,CDC5L,DYNC1I2,YWHAH,XPO1,YWHAG,MAP4,YWHAB,CAMSAP2,RIGI,KIF2A,ACTR1A,RAF1,ACTR2,CAPZA2,TUBB4B,SYBU,GSK3A,TUBA1B,CCNF,VIRMA,SRPK2,FBXO22,JAKMIP2,ARL6IP6,SFN,RIT1,MAPRE1,YWHAZ,DCTN3,HSPA8,MIS12,JAKMIP1,RPA3,RNF41,FBXW7,HSCB,CNPY3,FAXC,PAFAH1B1,TRIM36,DCTN4 |
| 5.464e-03 | -5.21 | RCL1 (RNA terminal phosphate cyclase like 1) | protein interactions | 10171 | 108 | 43 | 19454 | 5460 |
PSPC1,CTTN,PPP1R10,ESR2,MYC,GRB10,DNAJC8,ATG3,RC3H2,LMNB1,BRCA1,UBE2H,DNAJB6,RIT1,RPA3,SIRT7,UFL1,STAU1,AATF,RPA2,GRM2,NUFIP2,EED,TOP1,CDK9,MOV10,IFI16,XPO1,ATG7,PPIL4,DDRGK1,TTL,CHCHD1,SNIP1,KRAS,SSRP1,TFG,SERPINB9,RAF1,RPSA,DDX42,GEMIN7,TAF2 |
| 5.470e-03 | -5.21 | positive regulation of proteolysis involved in protein catabolic process | biological process | GO:1903052 | 132 | 53 | 18204 | 5365 |
USP5,CAV3,SUMO1,FBXO22,GSK3A,CDK5RAP3,TGFB1I1,PTEN,NFE2L2,CAV1,PSMC5,DISC1,PSMD10,DET1,RNF139,PSEN1,SGTA,TRIB1,CSNK1A1,DNAJB2,CCDC22,PSMC3,ATP5IF1,PIAS1,RGN,COP1,SOCS5,SMURF1,HECTD1,NUPR1,PSMC4,FZR1,CDC20,RCHY1,ZER1,CSNK1E,CTSC,ZFAND2A,MDM2,DDRGK1,TRAF7,FBXW7,SOCS4,GABARAP,SUMO2,AKT1,BAG2,NOP53,STUB1,CLU,GCLC,PSMC1,USP13 |
| 5.473e-03 | -5.21 | CNOT1 (CCR4-NOT transcription complex subunit 1) | protein interactions | 23019 | 285 | 100 | 19454 | 5460 |
BRD9,KRT8,FUBP3,FBXO32,NUP35,CNTROB,EGLN3,CCAR2,RPL7,PAIP1,HNRNPL,CPEB1,CNOT8,XPO1,IFI16,CNOT2,MED4,AGR2,ZC3H7A,PABPC1,LSM14A,ABCF1,ZYX,PAK6,TOB2,PSMD12,NUP42,G3BP1,KRAS,LGR4,SOX2,TOP3B,RAF1,MAX,GPBP1L1,EZH2,CNOT6,SCN2B,PRRC2A,ESR2,BTG3,FBXO22,FANCD2OS,BTF3,CUL3,DCAF4,BRCA1,GADD45B,FBXW11,CCT2,HSPA8,TXNL1,STAU1,YTHDF1,FXR2,TANK,NUFIP2,PPARG,CDC5L,MOV10,SSX2IP,GARRE1,CAPZA1,RIGI,CNOT6L,PDRG1,TOLLIP,CTNNBL1,CNOT7,AURKAIP1,TNRC6C,YTHDF2,CAPZA2,IZUMO1,TRIM24,ALB,RPS20,GTF2A1,SMAP2,CTTN,CCNF,VIRMA,DYRK1A,USP14,FBXO7,CEP85,UBE2H,MAPRE1,PAIP2,UHMK1,RC3H2,SQSTM1,SIRT7,RPA3,BAP1,SNAPC1,CDC42,BTG2,RPA2,SDCBP |
| 5.479e-03 | -5.21 | DBI (diazepam binding inhibitor, acyl-CoA binding protein) | protein interactions | 1622 | 34 | 17 | 19454 | 5460 |
PFDN2,RAD23B,DDIT4L,CRIP1,TSPO,MAP1LC3B,YKT6,SLC25A32,HSPE1,NSFL1C,LGALS3,SOD1,PEBP1,BAP1,UBE2N,HSPA8,MCL1 |
| 5.479e-03 | -5.21 | CMTM3 (CKLF like MARVEL transmembrane domain containing 3) | protein interactions | 123920 | 34 | 17 | 19454 | 5460 |
MOB3C,MFSD14B,MEST,GPR35,LMNA,SPP1,DDX39A,CSK,VEZT,RIGI,REEP4,GJB1,RABAC1,RETREG3,SYT2,HSD17B11,ELOVL4 |
| 5.479e-03 | -5.21 | GADD45B (growth arrest and DNA damage inducible beta) | protein interactions | 4616 | 34 | 17 | 19454 | 5460 |
CNOT6,GADD45A,EFHC1,PCNA,CNOT7,CNOT6L,GADD45G,EGR1,TOP3B,CNOT2,CCNB1,PPARA,CNOT8,CFTR,CDKN1A,CDK1,PPARG |
| 5.479e-03 | -5.21 | Tube1 (tubulin, epsilon 1) | protein interactions | 71924 | 34 | 17 | 19454 | 5460 |
SEC22B,CCT5,ETF1,TRAF3IP2,CCT2,TFRC,LAMTOR1,TBC1D4,XPOT,CCT8,TMEM263,TEDC2,BAG2,PC,TCP1,SRPRB,HSP90AB1 |
| 5.479e-03 | -5.21 | IFNAR2 (interferon alpha and beta receptor subunit 2) | protein interactions | 3455 | 34 | 17 | 19454 | 5460 |
APEX1,STAT1,STAT2,TRIM21,PRKCB,JAK1,RING1,STUB1,MAP3K11,IFNA2,HERC4,GRAP2,IFNB1,IFNAR1,RNF40,CREBBP,IRF9 |
| 5.479e-03 | -5.21 | TRAPPC2B (trafficking protein particle complex subunit 2B) | protein interactions | 10597 | 34 | 17 | 19454 | 5460 |
UQCC2,TRAPPC1,ZNF655,TRAPPC10,TRAPPC3,NME4,ZBED1,TRAPPC6B,SNAPC5,PRMT2,TRAPPC2L,TRAPPC14,TRAPPC6A,TRAPPC4,NICN1,TRAPPC13,LSM3 |
| 5.479e-03 | -5.21 | ANKRD34C (ankyrin repeat domain 34C) | protein interactions | 390616 | 34 | 17 | 19454 | 5460 |
NDUFS8,UQCRQ,PHB2,MGST3,NDUFS2,PDHB,HADHA,NDUFA4,PHB1,VDAC2,UQCRC2,CYC1,NDUFS3,PDHA1,TOMM40,UQCRC1,MTCH2 |
| 5.480e-03 | -5.21 | TMEM120B (transmembrane protein 120B) | protein interactions | 144404 | 111 | 44 | 19454 | 5460 |
ZDHHC15,TLCD4,HNRNPL,TNFSF18,HSD17B11,KCNA2,COMT,CRELD1,TMEM14B,CTLA4,YIPF3,TOP3B,RIGI,ALOX5AP,SLC7A14,GJB1,MRPS18B,GAD2,RUSF1,ATP5PF,FCER1G,SLC1A3,SCN3B,GPR17,MGST3,REEP4,RETREG3,SERINC1,DPEP1,ARL15,LMNA,STOM,MMP14,HCST,LRRTM2,BNIP3L,EMC1,RNF5,SLC7A1,LPAR1,CXCR4,JAGN1,TMX2,TSPAN15 |
| 5.480e-03 | -5.21 | MTR (5-methyltetrahydrofolate-homocysteine methyltransferase) | protein interactions | 4548 | 111 | 44 | 19454 | 5460 |
RHOH,EGLN3,CEP19,PHB1,EEF1AKMT3,ARL4D,SMAD4,HAX1,DCAF11,DNAJC7,UBXN6,MOV10,DNAJB2,B9D1,DHX16,LSM4,TGFBR2,HAPSTR1,THG1L,ILF2,RAF1,DYNLL1,VIRMA,CCNF,LMBR1L,KTI12,ANAPC2,LAMTOR1,RIT1,CALU,EMILIN1,CUL3,B9D2,NAPG,STAU1,RPA3,LGI1,RCCD1,HSPA8,ARPC2,RPA2,ATG16L1,INSYN2A,DET1 |
| 5.480e-03 | -5.21 | PLP2 (proteolipid protein 2) | protein interactions | 5355 | 111 | 44 | 19454 | 5460 |
KDELR2,PLP2,LMNA,LACC1,TMX2,MRPL41,MRPL57,RNF5,SCN3B,TM4SF19,FCER1G,CYB561,S100A11,CSGALNACT1,CYBC1,RETREG3,REEP4,MGST3,SPG21,SOX2,CD2BP2,AQP3,EZH2,TMEM31,TMEM14B,CCR1,ATP5PF,PTGES,HSD17B10,CYBRD1,HNRNPF,KRAS,FATE1,MRPL9,AQP2,PDZK1IP1,SYNCRIP,CLN8,HSD17B11,DLGAP4,FNDC9,DNAJC1,LHFPL1,CRB3 |
| 5.486e-03 | -5.21 | EIF2D (eukaryotic translation initiation factor 2D) | protein interactions | 1939 | 53 | 24 | 19454 | 5460 |
EIF1B,HSPA8,KIN,RPS28,HEXB,RPS11,PSMC3,ATG16L1,DHX15,CDC5L,RPS16,ACHE,RPS12,CCNF,PSPC1,RPS2,CALU,NIF3L1,EIF3G,BICD2,CSNK2A1,MYC,CUL3,GMPPB |
| 5.486e-03 | -5.21 | SPG11 (SPG11 vesicle trafficking associated, spatacsin) | protein interactions | 80208 | 53 | 24 | 19454 | 5460 |
HCST,AP5M1,SPRYD4,BAG2,RAB9A,ZC3H7A,CXCR4,TUSC2,CRYL1,CYFIP2,NPTN,GPR17,LAMP2,MYC,AP5S1,SERTAD3,VCPIP1,FIS1,DNAJC7,LAMTOR1,EEF1AKMT3,VIRMA,NCKAP1,FBXO22 |
| 5.486e-03 | -5.21 | IL2RA (interleukin 2 receptor subunit alpha) | protein interactions | 3559 | 53 | 24 | 19454 | 5460 |
NDUFB8,IL2,ICAM1,SMDT1,SNTA1,RHOBTB3,SLC30A5,MBLAC2,IL2RB,SLC25A46,NFKB1,SPPL3,TAMM41,IL2RA,CD4,ARL10,HGS,IL6ST,TMT1B,SACM1L,LPCAT3,ATP1A2,NDUFC2,ATP2B4 |
| 5.486e-03 | -5.21 | VAV3 (vav guanine nucleotide exchange factor 3) | protein interactions | 10451 | 53 | 24 | 19454 | 5460 |
DDX42,ZNF326,MET,RBFOX2,UBA52,KIT,ZYX,RINT1,FAM76B,IGF1R,RHOG,SHC1,TRAF6,CA2,SERPINH1,PIK3R1,AAMDC,CUL3,AR,NOP58,LCP2,TRAF1,PSPC1,GAB1 |
| 5.486e-03 | -5.21 | SMAD6 (SMAD family member 6) | protein interactions | 4091 | 53 | 24 | 19454 | 5460 |
SMURF1,SMAD5,PELI1,KPNA2,ACVR1B,TAB1,ACTR1B,MYD88,BMPR1A,CHRM5,SMAD2,LYZ,STAMBP,USP15,SMAD4,CTBP1,WWP1,ACVR1,BMPR2,SMAD1,BMPR1B,TNFAIP3,WWP2,CUL2 |
| 5.486e-03 | -5.21 | SEC11C (SEC11 homolog C, signal peptidase complex subunit) | protein interactions | 90701 | 53 | 24 | 19454 | 5460 |
STX12,PRSS23,CHRNB2,ALPL,TOMM22,CCDC47,VAMP1,CNPY3,PLPP6,SPCS2,TMEM243,TMEM254,TMEM42,SPCS3,BTN2A2,TMEM30A,SPCS1,PCSK9,FUNDC2,CYB5R3,FBXL14,SELENOM,DNASE1L1,GGT7 |
| 5.487e-03 | -5.21 | LPCAT1 (lysophosphatidylcholine acyltransferase 1) | protein interactions | 79888 | 120 | 47 | 19454 | 5460 |
RHOJ,LAMTOR3,APEX1,ESR2,VIRMA,LMBR1L,CCNF,FAS,RHOB,UBE2H,ILK,CUL3,NF2,HSCB,FBXW7,RHOU,RPA3,TSPAN15,HSPA8,DERL1,RPA2,SSR1,SEC62,CDC42,OTULINL,KLRD1,NEK7,CFTR,MARCHF4,EGLN3,RAMP3,CAV1,COQ8A,HSD17B11,TES,RHOG,PEX3,STYK1,MAPK4,ADIPOR2,KRAS,CDK20,RIGI,MDC1,RPN1,OTULIN,FAF2 |
| 5.491e-03 | -5.20 | PMF1 (polyamine modulated factor 1) | protein interactions | 11243 | 117 | 46 | 19454 | 5460 |
NDC80,CENPW,SHC3,SKIC8,TSNAX,ZDHHC15,GNPAT,YBEY,HNRNPL,COPS7B,NUF2,EGLN3,CENPM,SPC24,DDX39A,NFE2L2,CHAMP1,ZC4H2,CBX3,TAF2,EFHC1,CTNNBL1,PCGF6,DSN1,COPS7A,MLF1,PPP1CC,BICD2,ZMPSTE24,HSP90AA1,CRMP1,METAP2,UBE2S,SEC63,LRIF1,CBX5,ING5,ATG16L1,ADNP,MED31,SNAPC1,MIS12,CMTM6,PTN,KDM1A,NRBF2 |
| 5.515e-03 | -5.20 | nuclear receptor binding | molecular function | GO:0016922 | 136 | 55 | 18094 | 5411 |
HMGA1,SMARCE1,PHB2,TADA3,SMARCD3,WBP2,YWHAH,NR4A2,FOXP1,CALR,STAT1,DDX5,MED30,RNF14,PPID,NR1H2,GTF2B,ZNHIT3,KDM1A,LRIF1,C1D,SRC,TGFB1I1,TCF21,RERG,VDR,PRMT2,TAF7,PPARG,PROX1,FKBP4,THRAP3,TAF10,CRY1,MED17,BUD31,PADI2,ACTN4,NR0B1,NKX3-1,TRIM68,CTNNB1,MED4,JUP,NR1I2,PAGR1,TRIP4,PCNA,EP300,TOB2,SRARP,TRIM24,PRKCB,TAF11,SMAD3 |
| 5.520e-03 | -5.20 | P2RY8 (P2Y receptor family member 8) | protein interactions | 286530 | 175 | 65 | 19454 | 5460 |
FAM8A1,TM9SF1,GALNT1,SIGMAR1,SAMM50,SEC62,YIPF5,EDEM3,RABL3,DUSP14,COQ8B,TOMM22,MTX2,ZDHHC17,SLC5A6,CYFIP2,CMTM6,RER1,DERL1,ATP2C1,XPOT,VMP1,ATP1A3,NCAPG2,TM9SF4,VKORC1L1,TNPO3,CHP1,ARMC6,SLC30A7,SERINC1,CHCHD6,SLC1A1,HYCC1,SCAMP2,GNAZ,GNAQ,KDELR1,YIPF3,TUBA1A,AGPAT5,ARFGEF1,IPO8,FASTKD5,PSEN1,SACM1L,FANCG,ATP1A2,ACVR1B,SLC39A3,RUSF1,ATP2B4,PEX3,TMEM11,FAM241B,EXOC2,FAM20B,MSMO1,ECHDC1,ATXN10,DERL2,SLC39A10,DCK,C2CD2,STARD3NL |
| 5.520e-03 | -5.20 | CDK11B (cyclin dependent kinase 11B) | protein interactions | 984 | 175 | 65 | 19454 | 5460 |
URM1,VDR,MTA3,RAF1,RAP1A,MTA2,ZRANB2,TMEM14B,CDK8,TPPP,EZH2,IK,TCEA2,RPS27A,MEPCE,MRPS33,RBBP7,PCGF3,CSNK2A1,YWHAG,DDRGK1,EIF3D,IFI16,UBXN6,YWHAB,ANKRD50,UQCR11,SKIC8,SNRNP70,EEF1AKMT3,FBXO32,ZBTB2,NKAP,RFXANK,CDK7,SAP30BP,EHHADH,MFAP1,EPHX1,RPA2,HSPA8,YAF2,RPL27,RPA3,NLE1,MBD3,CCND3,PSENEN,NUCKS1,ANAPC15,PDE4B,MYC,CDC73,HSP90AA1,H1-1,YWHAZ,HEXIM2,CSNK2B,AP2M1,MSN,EZH1,ESR2,SNRNP40,RBBP4,FBXO22 |
| 5.520e-03 | -5.20 | XRCC3 (X-ray repair cross complementing 3) | protein interactions | 7517 | 175 | 65 | 19454 | 5460 |
GEMIN7,TIMM8A,TUBA1A,FARSA,CD80,KRAS,FANCG,FKBP8,CCAR1,RNF20,CCT8,HNRNPA2B1,SFXN1,HSPD1,S100B,PC,RABGGTB,ZC3H11A,SNRNP70,POLB,SSX2IP,HAX1,RBM17,LAMP2,PPIL4,LAMP3,XPO1,TCP1,KCTD10,HSP90AB1,ERLIN1,CDK9,TMPO,RBM5,HSP90B1,AGGF1,TOR1AIP2,TOMM22,SF3A1,INSYN2A,TIMM13,SSR3,PHB2,SLC31A1,NPTN,EIF5B,RNF5,UNC45A,BAP1,DERL1,SF3B1,ZNHIT3,ZSWIM7,SPCS3,CALU,DNAJC8,ATP5F1A,CXCL1,MED17,COPE,RPL10,TECR,APLNR,UQCRQ,PPP1R10 |
| 5.528e-03 | -5.20 | regulation of cardiac muscle contraction | biological process | GO:0055117 | 78 | 34 | 18204 | 5365 |
CLIC2,CAV1,MIR200C,STC1,EHD3,MIR1-1,CHGA,FKBP1B,UCN,FGF13,CAV3,SRI,MIR448,SUMO1,TMEM38B,PLN,RANGRF,KCNJ2,MIR30E,GSTO1,RGS2,GSTM2,JUP,ADRA1A,ADORA1,HSP90AA1,ATP1B1,TNNI3K,DLG1,SLC8A1,PDE4B,ATP1A2,ASB3,PIK3CG |
| 5.534e-03 | -5.20 | MAPK8 (mitogen-activated protein kinase 8) | protein interactions | 5599 | 247 | 88 | 19454 | 5460 |
NFE2,RUVBL1,PRPSAP1,CDKN2C,CCT8,LSM14A,CYB5B,SCAND1,GFPT1,JUN,TRAF2,FASLG,RAF1,ELK1,TCP1,COPS2,KRT8,RPLP2,YWHAB,BCL2L1,CDKN1B,CBL,TRAF6,PPM1B,CTNNB1,PIK3R1,GSTM3,UBXN6,EP300,HSPA8,NKAPD1,ANXA7,MAP2K1,PPARG,CDKN1A,ELK4,DUSP22,RFXANK,ELK3,BAD,SP1,BAX,HSP90AA1,YWHAZ,PNRC1,FAS,CCT2,MYC,PTGES3,CTSC,MAP1B,BMPR2,NFE2L2,TFCP2,TAF1D,H2AX,DUSP1,TP53,FZR1,RB1,PRR3,EEF1AKMT3,HRAS,WDCP,SSU72,SMAD3,SHC1,CAMP,LAMP3,BAK1,IRF3,PRPF4,SNCG,GSTP1,JKAMP,CDC42,RABL3,RSL24D1,DUSP10,JUNB,MSN,GANAB,SMAD2,GORASP2,USP14,FAM193B,CSK,AKT1 |
| 5.537e-03 | -5.20 | enzyme activator complex | cellular component | GO:0150005 | 16 | 10 | 19108 | 5553 |
LAMTOR1,RRAGA,PCNA,FLCN,LAMTOR2,LAMTOR3,SLC38A9,CCNH,MNAT1,CDK7 |
| 5.538e-03 | -5.20 | IPO4 (importin 4) | protein interactions | 79711 | 203 | 74 | 19454 | 5460 |
STOM,TCP11L1,RPA2,VAV2,TRMT112,MYL6,CDAN1,ATG16L1,CFTR,CDC42,EEF1G,FBXW7,NPTN,UFL1,COIL,SIRT7,BAP1,RPA3,EMG1,EP300,HSPA8,GSTK1,CDKN3,CUL3,MYC,AR,RBBP4,ATP5F1B,KCTD9,CTSB,APEX1,ESR2,VIRMA,SH3BGRL,CHRM4,RAN,ENO1,ZNF330,SCN2B,LMBR1L,CCNF,PTEN,PRMT5,SIGLECL1,TFRC,HGS,RANBP1,ARFGEF1,B3GNT2,TOP3B,COMTD1,TBK1,EEF2,SOX2,ASF1A,H3C1,ZC3H7A,EFNB1,HAPSTR1,RUVBL2,AGR2,SHC1,PEX3,DNAJC7,FAM174A,MOV10,DPP4,DDRGK1,PRNP,MYL12A,EGLN3,PTP4A3,SYNCRIP,TES |
| 5.551e-03 | -5.19 | YOD1 (YOD1 deubiquitinase) | protein interactions | 55432 | 70 | 30 | 19454 | 5460 |
CTNNB1,UFD1,TRIM8,LMO2,UBXN6,USP15,UPK1A,TRAF6,BLOC1S5,TRIM54,FCF1,ISG15,SOX2,FAF2,TANK,DDIT4L,CCR1,STX17,PLAA,FAM168A,MAVS,DERL1,UBE3A,SYVN1,BIRC2,NGRN,THOC3,RFC2,RBCK1,TRIM63 |
| 5.551e-03 | -5.19 | SLC12A6 (solute carrier family 12 member 6) | protein interactions | 9990 | 70 | 30 | 19454 | 5460 |
SLC4A8,OXSR1,VAV2,NRN1,RAB6B,RAB4A,RAB5A,RHOU,OR2A2,PDE2A,STX7,DPM2,RIGI,KRAS,RAB3B,SLC41A3,RAB2A,RAB5C,RHOG,LAMTOR1,LGALS8,RHOB,CD79B,CLRN2,STX6,CAV1,MARCHF4,HNRNPL,LGALS3,RHOH |
| 5.575e-03 | -5.19 | U12-type spliceosomal complex | cellular component | GO:0005689 | 28 | 15 | 19108 | 5553 |
SNRPD2,SNRNP48,SNRPB,SNRPD3,DHX15,SNRPD1,ZMAT5,SF3B6,SF3B1,RBM41,SF3B4,ZCRB1,SNRPE,SNRPG,SF3B5 |
| 5.578e-03 | -5.19 | regulation of RNA splicing | biological process | GO:0043484 | 185 | 71 | 18204 | 5365 |
SGF29,SF3B4,HNRNPH3,PRDX6,PRMT5,HNRNPK,SRSF7,NOVA1,SRSF12,HNRNPA2B1,SAP18,SRSF1,HSPA8,DYRK1A,TMBIM6,AKAP17A,HNRNPL,TAF9,RBM12,DDX5,MAGOH,WTAP,TAF10,HNRNPH2,ENY2,CLK4,THRAP3,SRPK2,HMX2,RBM7,HNRNPA1,PCBP4,WDR77,SRSF2,GRSF1,RBM3,SNRNP70,RBM15B,RBM23,ARB2A,SF3B5,RBFOX3,ILDR1,CIRBP,TADA3,PIK3R1,TRA2A,RBM22,TIA1,TAF5L,RBM38,PQBP1,RPS13,TRA2B,ZNF326,TADA1,SLC38A2,RPS26,CLK1,UPF3B,SRSF4,CELF6,SUPT7L,SMU1,SRSF10,SUPT3H,PRPF19,RBM5,RBM42,RBFOX2,HNRNPF |
| 5.578e-03 | -5.19 | response to carbohydrate | biological process | GO:0009743 | 185 | 71 | 18204 | 5365 |
ICAM1,RAF1,SMAD3,MAP2K3,IL1A,ACVR1C,SARM1,UCP2,PIK3CA,KCNB1,ADIPOQ,TNF,GPX1,MIR15A,CLTRN,EIF2B3,SOD2,GLUL,CLEC7A,IGF1R,MAP1B,GPAM,TWNK,IL1B,RAB11B,PPP3CA,HNF1B,SLC6A1,KCNJ11,RMI1,GCLC,PFKFB2,SELENOS,LEP,SELENOT,SMAD4,ITGA2,AGER,PPARA,FBP1,ZBED3,TXNIP,EGR1,SIN3A,PAX6,VAMP2,MAP2K6,ADNP,EIF2B2,TRA2B,MIRLET7G,MIR16-1,PRKCB,CMA1,FKBP1B,SESN2,SMAD2,MIR320A,CDKN1B,XBP1,PCK2,PLCB1,NQO1,EIF2B5,NPTX1,MIR146A,CCDC186,MIR221,OPRK1,SLC29A1,CYP7A1 |
| 5.596e-03 | -5.19 | PPP4R3A (protein phosphatase 4 regulatory subunit 3A) | protein interactions | 55671 | 172 | 64 | 19454 | 5460 |
MSH6,RIGI,G3BP1,HUWE1,TSSC4,RBBP7,PSMA2,AKAP12,KPNA2,ACTR1A,COMTD1,MARCKSL1,SUPT5H,DHX38,PPP4C,PPME1,MTA2,SF3B5,CASK,CDK8,IGBP1,PSMB1,PPP2CB,SRSF1,SNRPA1,OSBP,CCAR2,GAPDH,USP15,DDX23,UBXN10,CLK1,SF3B1,RNF113A,RPA3,NUCKS1,NSFL1C,SNRNP27,ALKBH3,H1-5,SF3A1,SYK,UBE2M,ARCN1,FKBP1A,ACACA,RPA2,CDK1,SNX12,SNRPD2,SF3B4,SF3B6,SNRPB2,DEK,APEX1,SNX3,SNRPB,CPSF2,DNAJC8,MCM4,SUB1,CUL3,PEA15,H1-1 |
| 5.596e-03 | -5.19 | HDGFL2 (HDGF like 2) | protein interactions | 84717 | 172 | 64 | 19454 | 5460 |
H2BC9,SMARCE1,DNAJC8,USP14,OSGEP,UBE2H,DNAJB6,RBBP8,PIP4K2C,CDC7,SYT2,CSNK2B,MACROH2A1,PTCRA,PARP2,APEX1,RPL22,MAD2L2,SNRNP40,ZCCHC7,FBXO22,SNRNP27,CDK7,ACTL6A,EPHX1,MACROH2A2,DNAJC27,LMNA,ADNP,IER2,BAP1,RPA3,HSCB,FBXW7,CSNK2A1,DDX23,DEGS1,MBD5,WIF1,PLGRKT,SEMA3C,H2AX,AURKAIP1,GTF2E2,B3GNT2,CIBAR1,ZRANB2,TAF2,NUPR1,CHAMP1,CBX3,DMAP1,EZH2,NFKBIL1,EWSR1,EMC2,BCL7B,TCOF1,CDCA7L,DUSP19,SSRP1,H3C1,DNAJC30,TOLLIP |
| 5.640e-03 | -5.18 | regulation of response to cytokine stimulus | biological process | GO:0060759 | 194 | 74 | 18204 | 5365 |
DICER1,MIRLET7C,MIR130A,PPARG,CCDC3,CPNE1,RNF113A,TBK1,MIR21,MIR20A,GFI1,IL1R2,IFIH1,TICAM2,STAT2,TLR2,EIF4E2,SPATA2,YTHDF2,CASP4,NKIRAS2,OAS1,SAMHD1,IL7,IRF7,RIGI,H2BC11,NLRP6,CAV1,LSM14A,CNOT7,TRIM44,NR1H2,MIR125A,MAVS,IKBKB,ISG15,CXCR4,IRF3,PTPN11,MIR152,MIR99A,KLF4,MIR98,STAP1,TLR4,TANK,PYCARD,EXT1,SYK,PPP2CB,OTULIN,PELI3,ANGPT1,PTPN1,NKIRAS1,DHX9,IL6,GSTP1,AGPAT1,TRAF2,TNFAIP3,TRIM32,TAF9,PADI2,TRIM6,PYDC2,CCL5,ADIPOQ,PAFAH1B1,MUL1,MIR24-1,MIR101-1,UBE2K |
| 5.651e-03 | -5.18 | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-astrocytoma_Grade_I | 36 | 18 | 16828 | 4835 |
FGFR1,PIK3CA,CTNNB1,GNA11,KIT,MET,TP53,NACC2,AKT1,PTPN11,IDH2,PPP2R1A,FBXW7,GNAQ,CLCN6,KRAS,HRAS,IDH1 |
| 5.654e-03 | -5.18 | Downstream signaling of activated FGFR1 | REACTOME pathways | R-HSA-5654687 | 31 | 17 | 10285 | 3229 |
PIK3R1,FGF3,SHC1,FRS3,FGF10,FGF1,FGF17,FLRT3,FGFR1,FGF23,PTPN11,KRAS,HRAS,GAB1,FLRT2,PIK3CA,FGF22 |
| 5.657e-03 | -5.17 | Transport of Mature Transcript to Cytoplasm | REACTOME pathways | R-HSA-72202 | 87 | 39 | 10285 | 3229 |
UPF3B,THOC2,CHTOP,MAGOHB,POLDIP3,THOC3,NUP62,NUP153,SLU7,NCBP2,DDX39B,NXT1,MIR939,CPSF1,FYTTD1,NUP35,NUP37,EIF4A3,DDX39A,CDC40,SRSF1,NUP50,ALYREF,DHX38,MIR636,CASC3,SRSF2,SRSF7,ZC3H11A,CPSF2,SRSF4,NUP42,THOC6,MAGOH,EIF4E,CPSF4,MIR1234,NUP107,THOC1 |
| 5.658e-03 | -5.17 | Chemokine_CC_CS | interpro domains | IPR000827 | 23 | 13 | 18521 | 5414 |
CCL23,CCL1,CCL28,CCL8,CCL2,CCL20,CCL4L1,CCL3,CCL19,CCL17,CCL5,CCL18,CCL11 |
| 5.660e-03 | -5.17 | Dual incision in TC-NER | REACTOME pathways | R-HSA-6782135 | 66 | 31 | 10285 | 3229 |
RFC4,TCEA1,UBB,GTF2H2,RPS27A,UBA52,POLR2D,POLR2L,GTF2H5,POLR2G,POLE3,POLR2F,PCNA,RFC3,POLR2B,EP300,MNAT1,CDK7,RFC5,RPA3,PRPF19,RPA2,POLD2,POLR2I,CCNH,POLR2C,GTF2H4,ERCC3,POLE4,POLD4,RFC2 |
| 5.662e-03 | -5.17 | positive regulation of protein ubiquitination | biological process | GO:0031398 | 112 | 46 | 18204 | 5365 |
DERL1,CDK5RAP3,GSK3A,WBP1L,CRY1,RBCK1,NMI,KDM1A,NSMCE3,PSMD10,PHF23,CAV1,TICAM1,PTEN,UBE2D1,UBE2S,UBE2N,RPS2,ARRDC3,TOPORS,SKP1,TRAF6,NDFIP1,HSPA5,CDKN1B,CUL3,HDAC3,CDC20,FZR1,UBB,BIRC2,UBE2L3,RCHY1,UBE3A,MAGEC2,PELI1,GABARAP,FBXW7,HUWE1,BCL10,ANGPT1,UBE2V1,FAM107A,STUB1,UBE2V2,PTPN22 |
| 5.671e-03 | -5.17 | PHF8 (PHD finger protein 8) | protein interactions | 23133 | 169 | 63 | 19454 | 5460 |
NUDCD3,TULP3,CKS1B,ZNF263,SUPT5H,KLHL26,POLR2C,RBPJ,RPN1,CTSA,MAD2L1BP,RPS24,COX8A,RPL31,S100B,TRIM26,H3C1,LSM4,DDRGK1,WWP2,CDC26,MRPS35,CDC23,TOPBP1,BRD3,CSTA,DDX23,PHB1,EGLN3,KLF9,FZR1,CGAS,SUMO2,CCNA2,H1-5,CDK1,APOBEC3C,HSPA8,POLD2,COIL,AZGP1,KDM1A,ANAPC15,CDC16,MYC,OST4,CUL3,ANAPC4,LSM14B,PRMT5,CSNK2B,RPS20,ANAPC2,MACROH2A1,VDAC2,ELK3,ZNF330,CDC20,MAD2L1,ESR2,APEX1,TRIM29,SNRNP40 |
| 5.671e-03 | -5.17 | HMGN2 (high mobility group nucleosomal binding domain 2) | protein interactions | 3151 | 169 | 63 | 19454 | 5460 |
RHOH,TMPO,TSG101,H2AC4,CDK12,CLPX,BAZ1B,ASF1A,TOLLIP,HMGN4,KRAS,H3C1,MDC1,ABCF1,RPL31,RPL23A,CBX3,TPPP,TBC1D4,GBE1,TOP3B,TBK1,RAF1,PRDX2,HPF1,APEX1,SRPK2,PARP2,EIF2AK2,OPTN,ARF1,MACROH2A1,UBE2I,MECP2,H1-1,UBE2H,PDCD4,STAC3,MYC,RPF2,CAPG,USP14,H2BC9,H2AC13,PIAS1,CHMP2B,PYGB,SLU7,ATPAF2,RAB5A,EP300,HSPA8,CHMP1A,OSER1,SHOC2,MACROH2A2,PRKCA,TFIP11,RPL26L1,CFAP418,ATG16L1,H1-5,IGFBP3 |
| 5.677e-03 | -5.17 | negative regulation of proteolysis | biological process | GO:0045861 | 230 | 86 | 18204 | 5365 |
RPS7,HDAC6,MIR152,CCAR2,TM4SF20,AKT1,SERPIND1,SPOCK1,NOP53,HFE,SIAH2,CDK5,TAF9,SERPINB1,LAMP3,GPX1,SVIP,DPEP1,DDRGK1,TNF,MIR24-1,RAF1,IL10,CSTA,CAAP1,CSTB,PAK2,MIRLET7B,F2,IGBP1,IL1R2,SNX12,MIR17,CSNK2A1,PIH1D1,MIR29C,USP14,NR1H2,DNAJC1,MIR339,PML,KLF4,PRNP,RNF34,SERPINA5,IFI6,SERPINI1,TIMP4,SRC,SERPINH1,USP38,TIMP3,ROCK1,SERPINB11,MIR126,SERPINA1,FHIT,MMP9,CAMLG,CST3,MDM2,EPHA4,TP53,IFI16,AQP11,SFN,DNAJB6,RPL23,PSEN1,SGTA,MTM1,OPHN1,GABARAPL2,SERPINB6,SERPINB10,SUFU,CDKN2D,HSP90AB1,VEGFA,TIMP1,USP5,SERPINA3,CLN8,PRMT6,SERPINB9,GAPDH |
| 5.687e-03 | -5.17 | InlA-mediated entry of Listeria monocytogenes into host cells | REACTOME pathways | R-HSA-8876493 | 9 | 7 | 10285 | 3229 |
RPS27A,UBA52,UBB,CTNNB1,SRC,CTNND1,CBLL1 |
| 5.688e-03 | -5.17 | FAM174A (family with sequence similarity 174 member A) | protein interactions | 345757 | 222 | 80 | 19454 | 5460 |
HDHD5,ATXN10,EIF2B2,EIF2B5,ECHDC1,ANKRD46,FAM118B,MAP1S,FAM20B,CBR4,TMEM42,TMEM11,PDCD10,ATP2B4,BCKDK,EHD4,NDUFB5,STX8,PC,HAPSTR1,SLC39A7,RAB13,ERG28,JAK1,PRPSAP1,PLPP6,RAB18,MSH6,FKBP8,PRPS1,IPO8,TP53,CCDC47,RAF1,TNPO2,TUBA1A,UCKL1,FAM91A1,CINP,VAMP3,OAF,UMPS,TUBB,TAMM41,TNPO3,MAD2L2,TM9SF4,NCAPG2,SAMHD1,PPTC7,RPS6KA4,ATP1A3,VMP1,TMEM168,ATP2C1,UGDH,TMEM243,TMEM203,RLIM,STK26,NPTN,STX7,TOR1AIP2,FUT8,SEC22B,GOSR2,BET1,MTX2,NCALD,CNP,CCDC167,KDELR2,SEC22A,EHD1,TCP11L1,PLAA,GALNT1,SMCO4,VAPB,CMTM7 |
| 5.690e-03 | -5.17 | purine-containing compound biosynthetic process | biological process | GO:0072522 | 224 | 84 | 18204 | 5365 |
DLAT,ACSS2,NDUFS8,MTHFD2L,NDUFA1,NDUFAB1,NME1,PPAT,ATP5F1A,NDUFB10,PNP,NME2,PDHB,NDUFA12,ATP5MK,COX11,ATP5MC3,NDUFB7,NDUFA5,ADK,NDUFS2,GMPS,HACD2,MMUT,IDO1,ATP5MG,PPT1,NMRK1,ELOVL3,ACSL4,STOML2,DNAJC30,UQCC3,SHMT1,ATP5PB,NUDT2,PRPS1,SLC25A1,ATP5PD,NDUFB6,NPR2,NDUFV2,ATP5F1B,TECR,PRPSAP1,NDUFS6,GUK1,ATP5PF,MTAP,NDUFC2,NUDT12,PDHA1,SDHC,NDUFB8,ACAT1,PAPSS2,NDUFA2,LIPA,SDHB,ELOVL4,ATP5PO,AK5,ELOVL6,DCAKD,AK2,ELOVL7,HACD1,ADSS2,NPPC,NDUFB4,ADCY3,ATP6V1A,ATP5F1E,DCK,AK3,ACACA,NDUFS3,ELOVL1,ATP5F1D,ATP5MC1,NDUFB5,NME4,GUCY1B1,ADCY2 |
| 5.697e-03 | -5.17 | Telomere C-strand (Lagging Strand) Synthesis | REACTOME pathways | R-HSA-174417 | 24 | 14 | 10285 | 3229 |
POLD2,RPA2,PRIM2,RFC4,PCNA,POLE3,FEN1,POLE4,RFC3,POLA2,RFC2,RPA3,POLD4,RFC5 |
| 5.702e-03 | -5.17 | TNF_1 | prosite domains | PS00251 | 12 | 8 | 12186 | 3388 |
TNFSF10,TNFSF8,TNFSF13,CD40LG,TNF,FASLG,LTA,LTB |
| 5.719e-03 | -5.16 | APC (APC regulator of WNT signaling pathway) | protein interactions | 324 | 327 | 113 | 19454 | 5460 |
IL22,CTBP1,MAP2K1,CSNK1A1,ANXA7,SLU7,SPECC1L,STAU1,FBXO30,CREBBP,SFN,LIN7B,PSMD1,MYO6,FBXW11,YWHAZ,DCAF4,FTSJ3,HTRA2,DKK3,FAM83B,SMU1,AP2M1,PHF21A,ANAPC2,SIAH1,TAX1BP1,MAD2L1,CSNK1E,DLG3,NUP153,TUBB4B,SMARCB1,HGS,ZYX,TRIM21,PCNA,RUVBL2,USP30,NUP42,ANP32B,FLOT1,TAX1BP3,PPP2R5A,MARCHF5,SAV1,XPO1,YWHAG,YWHAH,CTNNB1,MRPL18,RB1CC1,YWHAB,RAB35,CCDC71,GJA1,KRT8,EGLN3,DIRAS3,RBFOX2,SPTBN1,ATG16L1,ING5,CFTR,RPA2,JUP,RNF146,TMOD1,TRIM36,HECTD1,LIN7C,DVL2,CYP17A1,KDM1A,TOMM20,HSPA5,TRIM32,CEP85,ARHGAP21,CTNNBIP1,PPP1CC,PKNOX1,MAPRE1,CASC3,CTNNA1,CSNK2B,GSK3A,BUB3,RPGRIP1L,VIRMA,TRAF1,FBP1,CDK4,EMILIN3,PPP3R2,SMAD1,PIK3CA,CASK,NUP107,RIGI,CYTH2,COPS5,CSNK2A1,CCL5,CRBN,USP15,TNKS,NAT2,MAPRE2,PRNP,MBD5,CDK9,CAV1 |
| 5.726e-03 | -5.16 | AGAP3 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 3) | protein interactions | 116988 | 73 | 31 | 19454 | 5460 |
TOP3B,JPH4,RPA2,NUFIP2,AGAP1,S100B,HSPA8,FLCN,MTDH,HSCB,SLC31A1,FGF12,AHCYL1,ZCCHC10,YWHAH,YWHAG,RACGAP1,UBE2H,BRD3,HSPB1,YWHAB,CCNF,TNFRSF1B,EEF1AKMT3,ARF6,STAT1,HNRNPL,PRNP,TSC22D3,ESR2,CETN2 |
| 5.726e-03 | -5.16 | IFI30 (IFI30 lysosomal thiol reductase) | protein interactions | 10437 | 73 | 31 | 19454 | 5460 |
MTMR6,ELP3,TRIM68,TMOD1,CSNK1A1,CXCL3,TMEM106B,TIMP3,MKLN1,EGFL7,ZNF692,G3BP1,MRPS7,G3BP2,NPTX1,DEPDC1B,B9D1,BRCA1,GTPBP2,RPL9,SSBP1,SNX12,FAM43A,B4GALT1,ARL4D,USP46,DAPK1,GFOD1,ACTB,USP5,RPL10 |
| 5.726e-03 | -5.16 | AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase) | protein interactions | 60496 | 73 | 31 | 19454 | 5460 |
PPP1R3C,EGLN3,CTSB,RAB14,PRNP,UMPS,SIAH1,SGTA,CCNF,MARCHF3,TRAPPC4,UBE2H,TMEM183A,HNRNPA1,MDFI,MOV10,BABAM1,HSCB,G3BP1,NMRAL1,SOD1,RPA3,EHD4,RPA2,ADSS2,GTF2IRD1,CAPZA2,TRAF2,EHD1,TULP3,UBLCP1 |
| 5.726e-03 | -5.16 | SCGN (secretagogin, EF-hand calcium binding protein) | protein interactions | 10590 | 73 | 31 | 19454 | 5460 |
ZMYM4,EBLN2,OSR2,STX12,AGGF1,VAMP2,SNAP23,STX8,STX7,PIP4P1,CNOT6L,VAMP8,CNOT7,CNOT8,ATP5F1A,MLF2,CNOT2,CDC23,ESYT1,PPM1B,STX10,VAMP3,CNOT6,EXTL2,STX6,VAMP7,STK3,JUNB,DDAH2,VTI1B,SNAP25 |
| 5.726e-03 | -5.16 | CENPK (centromere protein K) | protein interactions | 64105 | 73 | 31 | 19454 | 5460 |
MAPRE1,RIT1,HSPB1,CDC23,ZDHHC15,PTTG1,FAS,SKIC8,CENPL,COPS5,APEX1,CSTF3,YES1,BUB3,AP1G2,VPS72,LUC7L3,SKA3,PPP2R1A,ANAPC13,CENPM,PAFAH1B1,COPS4,PPWD1,PSMD12,TRIM63,KRAS,TRA2B,SRSF7,SPECC1L,MRFAP1L1 |
| 5.739e-03 | -5.16 | positive regulation of chemotaxis | biological process | GO:0050921 | 141 | 56 | 18204 | 5365 |
CCR1,VEGFA,SWAP70,BMPR2,IL23A,MSTN,TPBG,CXCL10,NRP1,TIRAP,TMSB4X,IL34,AIF1,CCL19,CCR2,NTRK3,CXCL13,PTN,CCL21,MET,CCL1,RARRES2,IL6,CX3CR1,FGF10,P2RY12,HSPB1,TIAM1,GPSM3,LPAR1,CXCL8,CCL5,F7,CALR,XCL1,SMAD3,DEFB124,CXCR4,CDH13,CCR7,OXSR1,CCR6,SEMA5A,ITGA2,VEGFC,CREB3,AGER,RAC2,CCR4,CCL3,FGF16,FGFR1,HMGB1,CXCL12,SCG2,IL12A |
| 5.741e-03 | -5.16 | regulation of synaptic vesicle exocytosis | biological process | GO:2000300 | 43 | 21 | 18204 | 5365 |
RAP1B,RAB3A,SLC4A8,PRKCB,CACNB4,SYT4,RAP1A,SNAPIN,SV2B,VPS18,PREPL,NLGN1,PPFIA2,RAB5A,RIMS3,RIMS4,SYP,WNT7A,CASK,P2RY1,P2RY4 |
| 5.745e-03 | -5.16 | RBM11 (RNA binding motif protein 11) | protein interactions | 54033 | 166 | 62 | 19454 | 5460 |
RBM7,COP1,DCAF4,LMNB1,ATOSB,TTC33,PYCR2,CNTNAP1,CEP85,CIAO1,RAB2A,SPRED1,PRRC2A,CHCHD3,SNRNP40,CTSB,PSMD4,SEC61B,PHF21A,SCNM1,ZNF189,CCNF,STAMBP,CRYAB,ATG16L1,PDHB,KDM1A,AKAP1,MED13L,HSPA8,NLE1,SNRPA,MED4,CHCHD1,SNRNP70,KLHL22,RAB5C,RBFOX3,DPP4,KLHL9,HMG20A,ZNF7,DIRAS3,THOC1,WDR82,EED,COX4I1,METAP1,ETV6,NEFL,GABPB1,VPS33A,TFRC,ELF1,AURKAIP1,TOP3B,ENKD1,RBBP7,MAN1A2,BHLHE40,SCYL2,CYP2C9 |
| 5.750e-03 | -5.16 | CCCHEMOKINER | prints domains | PR00657 | 16 | 10 | 5227 | 1528 |
CCR5,CCR4,CCR2,CCR6,CCR3,CCR7,CCR1,CXCR4,CXCR3,CXCR6 |
| 5.761e-03 | -5.16 | ERAD pathway | biological process | GO:0036503 | 95 | 40 | 18204 | 5365 |
EDEM1,RNF103,RNF139,TMUB2,OS9,RNF121,ERLIN2,CALR,HSP90B1,TMUB1,ERLIN1,SYVN1,FAF1,EDEM3,ERLEC1,DERL1,FAF2,UBE2G2,HSPA5,STUB1,DNAJC10,UFD1,XBP1,CCDC47,MAN1A2,SEC61B,SDF2L1,DERL2,EDEM2,RNF5,FAM8A1,HM13,SELENOS,SGTA,UBXN10,UBXN6,FBXO44,DNAJB2,DNAJB9,JKAMP |
| 5.783e-03 | -5.15 | TRASH | smart domains | SM00746 | 8 | 6 | 9717 | 2575 |
ZMYM6,ZMYM2,ZMYM3,RSL24D1,RPL24,ZMYM4 |
| 5.783e-03 | -5.15 | DWB | smart domains | SM00524 | 8 | 6 | 9717 | 2575 |
SMAD2,SMAD1,SMAD9,SMAD4,SMAD3,SMAD5 |
| 5.783e-03 | -5.15 | Proteasome_A_N | smart domains | SM00948 | 8 | 6 | 9717 | 2575 |
PSMA2,PSMA6,PSMA3,PSMA5,PSMA4,PSMA1 |
| 5.794e-03 | -5.15 | TRIM29 (tripartite motif containing 29) | protein interactions | 23650 | 219 | 79 | 19454 | 5460 |
HCLS1,NRSN1,RPS10,CPLX3,LRWD1,PTDSS1,TAX1BP3,HMGA1,RAB32,MOV10,XPO1,GTF2E1,NPSR1,TRAF6,AGPAT1,SMAD9,FBXO3,TRIM11,HINT1,OAZ3,RUVBL2,RUVBL1,H3C1,RFC2,MSH6,RFC3,MDC1,RPS4X,KHDC4,FCF1,H2AX,SOX2,EEF1A1,CAPZA2,DISC1,DMAP1,RNF8,POLR2D,CCR1,TAB2,UBE2I,TRIM27,TAB1,TUBB,TRIM29,JAKMIP2,CHCHD3,SEC13,RAB11A,TXNRD2,CEP70,RFC5,RPL26,BTF3,H1-10,TRIM23,BRCA1,GCC1,ZBTB38,SLC6A1,NBN,RFC4,SNAPC1,DVL2,NUP50,SMC4,PHB2,FXR2,HSPA5,SLC37A4,FBXL4,SSBP2,ACTL6A,CFTR,KDELR2,FBXL19,STX17,PRKCA,E2F6 |
| 5.794e-03 | -5.15 | PAK1 (p21 (RAC1) activated kinase 1) | protein interactions | 5058 | 219 | 79 | 19454 | 5460 |
AIFM1,DYRK1B,MAPK4,TAX1BP3,BMPR1B,XPO1,CSNK2A1,YWHAG,SHC1,NCK1,SMAD4,HSPB1,SLC25A11,SLC25A5,ZC3H7A,CDK5,SLC39A7,RUVBL2,PRPSAP1,RUVBL1,TGFBR2,TMEM33,HIGD1C,PAK1IP1,AKAP12,H3C1,PRPS1,RAF1,SMAD1,H2AX,TUBA1A,SOX2,ACVR1,TUBB4B,HGS,CDK5R1,TUBA1B,BAD,ZBTB18,TRIM27,RHOJ,SLC25A4,TUBB,PPAT,DYNLL1,USP16,BTG3,GNB1,SMURF1,POLR2B,TECR,MAT2B,PYCARD,CSK,SLC25A1,AKT1,YWHAZ,MYO6,IVNS1ABP,CHORDC1,SMAD2,ICAM1,HSP90AA1,PML,ARHGEF6,RHOU,HSPA8,NF2,BCL6,TPT1,PAQR3,LPXN,CDC42,MAP2K1,PAK2,CYC1,SLC25A3,OXSR1,GIT2 |
| 5.797e-03 | -5.15 | H1-2 (H1.2 linker histone, cluster member) | protein interactions | 3006 | 542 | 179 | 19454 | 5460 |
RPF1,RPL35,CALY,RPL37A,ZNF22,RAN,RPS5,SETD7,FYTTD1,DCAF4,LMNB1,ZCRB1,WDR20,MAP3K21,CUL3,CUL2,GRB10,PYGB,NUP50,H1-5,GJA1,HP1BP3,FOLR1,MRTO4,HNRNPD,SKIC8,WDR12,KDM2A,HMGA1,IRAK4,TNF,TRIM37,RPS24,PREPL,PPAN,EZH2,CHMP4C,MAK16,GTF2E2,VIRMA,NDN,PRKRA,UBASH3B,OPTN,CCNF,MRPL53,F10,EIF2AK2,CDC73,RPL26,PPP1CC,USP14,UTP23,AATF,BRIX1,NUCKS1,PRKCB,RPA3,HELLS,RPLP0,SHOC2,LMNA,HSP90B1,H2AC7,METTL14,CDK7,ZBTB2,NOP9,G6PD,NAT2,TOP1,PWP2,TES,AIFM1,H2AZ1,KRR1,EHBP1,TOPBP1,MPHOSPH10,MOV10,H2AC14,RNF20,VRK1,ZC3H11A,FAF1,APEH,TAF1D,ESR2,TRIM29,SNRNP40,GTF2F1,CMTR1,ICAM1,COP1,SLC15A2,H1-1,FTSJ3,PSMD14,H1-10,BTF3,MYC,SFN,STAU1,EEF1G,HSPA8,HDAC5,YAF2,RAB5A,AKAP1,PIH1D1,PAFAH1B1,FGF17,ISG20L2,RPS10,HNRNPL,SSPN,EED,AGR2,CTNNB1,IFI16,BAZ1B,DCAF4L2,WWP2,RPL28,NUP42,RUVBL2,SETD4,GALC,RPL31,GLE1,H1-3,SMURF1,PHAX,GTF2H2,MACROH2A1,RPS3,BICD2,H2BC9,RPS17,PRKACB,ZSCAN25,RPF2,HSPA5,RPS15,MRPL40,RNF113A,DERL1,BAP1,PML,NBN,BANF1,HEXIM1,PRKCA,RPA2,RNF146,DKC1,CAND1,RPS2,RPL24,SNRNP70,H2AC4,SAT2,CD81,COPS5,MEPCE,NEDD8,H3C1,RPL3,ABCE1,TBC1D4,NUPR1,RNF8,NECAP1,H2AX,STRBP,IMP3,RRM1,KBTBD4,TP53 |
| 5.798e-03 | -5.15 | Syntaxin | interpro domains | IPR045242 | 16 | 10 | 18521 | 5414 |
STX6,STX1A,STX10,STX17,STX12,STX8,STX16,STX7,STX11,STX5 |
| 5.798e-03 | -5.15 | Chemokine_rcpt | interpro domains | IPR000355 | 16 | 10 | 18521 | 5414 |
CXCR3,CCR6,CCR4,CXCR4,CCR7,CCR1,CCR3,CCR5,CCR2,CXCR6 |
| 5.801e-03 | -5.15 | SDR_fam | interpro domains | IPR002347 | 54 | 25 | 18521 | 5414 |
HSD17B10,DECR2,DHRS3,DHRS7B,SDR16C5,HSD17B8,DHRS4,KDSR,HSD17B6,RDH10,SPR,HSDL2,RDH11,RDH12,HSD11B1,CBR4,DHRS11,HSDL1,HSD17B11,DHRS7,HSD17B3,HSD17B1,CBR3,DHRS1,DHRS13 |
| 5.801e-03 | -5.15 | UBQ-conjugating_enzyme/RWD | interpro domains | IPR016135 | 54 | 25 | 18521 | 5414 |
KRAS,UBE2H,UBE2E3,UBE2E2,UBE2V1,UBE2B,UBE2W,UBE2F,RWDD4,IMPACT,UBE2N,UBE2G2,UBE2M,UBE2V2,UBE2S,UBE2A,UBE2K,UBE2I,RWDD1,TSG101,RWDD3,UBE2D1,UBE2D3,UBE2L3,RNF14 |
| 5.801e-03 | -5.15 | bZIP | interpro domains | IPR004827 | 54 | 25 | 18521 | 5414 |
NFE2L1,NFE2L2,JUNB,MAFG,DDIT3,CREB1,BACH1,JUN,ATF1,XBP1,FOSL2,CEBPE,BATF,CREB3L4,ATF4,CREBL2,NFE2,FOS,CREBZF,TEF,HLF,CREB3,NFIL3,ATF3,CEBPG |
| 5.814e-03 | -5.15 | ribosome assembly | biological process | GO:0042255 | 59 | 27 | 18204 | 5365 |
RPL10,MRPS7,NOP53,RRP7A,RPL10L,PWP2,RPS27L,TRAF7,RPS15,XRCC5,BRIX1,RPS28,NOA1,RPF2,MPV17L2,RPSA,NLE1,NGRN,EIF1AX,PPAN,RPS14,EIF5B,RPS5,RPL6,RPL23A,MRM2,RPLP0 |
| 5.821e-03 | -5.15 | HLA-DMB (major histocompatibility complex, class II, DM beta) | protein interactions | 3109 | 56 | 25 | 19454 | 5460 |
TAPBP,TEX264,PSEN2,RAB29,RDH11,DPM2,ARL5B,ACVR1B,TUBA1A,PREB,ARFGEF1,FDFT1,DHRS7B,SLC12A2,DECR2,ODR4,ACSL4,CD63,MDM2,TMBIM6,RETSAT,CUL3,DHRS7,ATP1A3,SMPD2 |
| 5.821e-03 | -5.15 | FAM24B (family with sequence similarity 24 member B) | protein interactions | 196792 | 56 | 25 | 19454 | 5460 |
CLRN1,FAM3C,PAK2,H2BC11,CRABP2,HPCAL1,FEN1,SERPINB9,LASP1,TXNL1,PDCD10,SERPINB1,NME2,CHORDC1,HMGCS1,CAPG,GALE,HSBP1,ZNF622,IL18,TES,MACROH2A1,ALDH1A3,VAMP3,CYRIB |
| 5.821e-03 | -5.15 | MLH3 (mutL homolog 3) | protein interactions | 27030 | 56 | 25 | 19454 | 5460 |
PCNA,GALNT12,SEC61B,HRAS,PPP2CB,ZDHHC17,ANP32B,MLH3,TRIM63,IGFBP3,HSD17B3,AR,PPP3R2,SMAD1,FBP1,MYC,AKT1,CUL3,TMOD1,CDK8,FBP2,STX17,MAP2K1,TDRD7,BPNT2 |
| 5.821e-03 | -5.15 | AKR1A1 (aldo-keto reductase family 1 member A1) | protein interactions | 10327 | 56 | 25 | 19454 | 5460 |
TP53,SOX2,GNPDA2,RPA2,BAP1,SOD1,RPA3,ARFIP1,PGK1,HSPA8,EXOSC4,SLC25A32,SAR1B,ACO2,GAPDH,CFL1,SLC16A4,NME2,AKR1B1,SNX12,SNX3,TENT5C,CAV1,DYRK1A,SH3BGRL |
| 5.821e-03 | -5.15 | organelle transport along microtubule | biological process | GO:0072384 | 81 | 35 | 18204 | 5365 |
HDAC6,TRIM46,BORCS5,AP3S2,KIF1C,BICD2,BLOC1S5,NDE1,MGARP,NEFL,HSBP1,RAB6A,KXD1,RAB1A,FBXW11,MREG,MAP1B,BORCS7,BLOC1S3,KIF3B,SNAPIN,UBB,TUBA1A,ARHGAP21,CDC42,BLOC1S2,CDR2L,BORCS6,DYNC1I1,TRAK2,PAFAH1B1,MAP1S,BORCS8,ARMCX3,SYBU |
| 5.834e-03 | -5.14 | ACTR3 (actin related protein 3) | protein interactions | 10096 | 276 | 97 | 19454 | 5460 |
STXBP1,PPP1CB,FKBP10,FOS,STK26,HSPA8,STAU1,EIF1B,WASF3,MYC,BTF3,BLVRA,CCT2,VMP1,PFDN6,PFDN2,ACTB,STAT1,TNPO3,ESR2,B3GNT2,TOP3B,RAF1,SOX2,NUDCD3,CHMP4C,SKA3,EZH2,CSTPP1,CCT8,TRIP4,UBE3A,TRIM37,KRAS,LASP1,HNRNPF,ANP32B,RAD21,PFDN5,IFI16,ACTR3B,XPO1,AGR2,ARMC8,YWHAB,CORO1C,TCP1,HNRNPL,CCT7,CFTR,CDC42,SIPA1L1,METTL14,HSP90B1,RPRD1B,RPA2,SIRT7,DVL2,BAP1,RPA3,ARPC2,HSPA5,DHPS,AR,USP14,PPP1CC,PRKACB,BICD2,NIF3L1,CALU,MAPRE1,UBE2H,CTTN,CCNF,MOB4,DAPK1,CEP97,SH3BGRL,CCT5,KIF1C,TP53,FBP1,CAPZA2,ARPC3,ACTR2,TFRC,NUPR1,SH3GLB1,PPP1R12A,HSD17B10,WASL,EMC4,HDAC6,HCLS1,SPPL3,TMPO,CDK9 |
| 5.834e-03 | -5.14 | BANP (BTG3 associated nuclear protein) | protein interactions | 54971 | 276 | 97 | 19454 | 5460 |
PPIC,NFKB1,HDAC6,PID1,RPAIN,MDM2,EEF1AKMT3,OLFM2,GATAD1,SAPCD1,C1QC,GFM2,MSRB3,TP53,SP4,PPIF,ZNF581,H2AX,ANAPC11,RIGI,SNX5,FGFR1OP2,KCTD9,CDC20,RPP25,GARIN6,CCNF,CIB2,DNASE1L1,CSNK2B,HEXIM2,UBE2I,ZMYM6,TOX4,LSM2,CCL18,SGF29,PDHB,STK38,PML,LGI1,FAM222B,FLCN,TOX,MDFI,UBXN6,PPIB,INSYN1,TRIM35,HNRNPL,RHOH,SP2,POLR2L,PSORS1C2,MAX,TOP3B,KHDC4,JUN,TRAF2,SNAPIN,KRAS,IGF1,POLDIP3,FLOT1,ENKD1,PAX6,AHCYL1,TRIM11,PFDN4,RIT1,MAF1,LMO2,NFYA,SFN,BTF3,SNRPB,TTC23,RIMS3,LRIF1,BTG3,VMAC,GNG12,NFKBIB,HAPLN2,CDC7,PHF21A,MAP2K1,SRARP,LAP3,RFXANK,KRTAP8-1,ISCU,LMO4,LMO3,CDSN,NGRN,EP300 |
| 5.845e-03 | -5.14 | Gamma-carboxylation, transport, and amino-terminal cleavage of proteins | REACTOME pathways | R-HSA-159854 | 11 | 8 | 10285 | 3229 |
F7,BGLAP,PROS1,F10,F9,F2,GGCX,FURIN |
| 5.845e-03 | -5.14 | Interleukin-6 signaling | REACTOME pathways | R-HSA-1059683 | 11 | 8 | 10285 | 3229 |
JAK2,SOCS3,PTPN11,JAK1,IL6,STAT1,CBL,IL6ST |
| 5.845e-03 | -5.14 | ATF6 (ATF6-alpha) activates chaperone genes | REACTOME pathways | R-HSA-381183 | 11 | 8 | 10285 | 3229 |
NFYA,NFYB,DDIT3,XBP1,HSP90B1,CALR,HSPA5,ATF4 |
| 5.881e-03 | -5.14 | DECR1 (2,4-dienoyl-CoA reductase 1) | protein interactions | 1666 | 76 | 32 | 19454 | 5460 |
NUPR1,HGS,SAP30,TP53,RAF1,ATG16L1,FBP1,MSH6,TRIM26,NF2,SOD1,UGDH,CBL,PTTG1,CCDC22,SNRNP70,SPOP,RHOG,COMMD5,WWP2,CREB3,CTSD,MYC,CHMP2A,ESR2,RPL10,FAM118B,MALSU1,DYNC1I2,TXN,HEBP1,FBXO32 |
| 5.881e-03 | -5.14 | KIAA1549 (KIAA1549) | protein interactions | 57670 | 76 | 32 | 19454 | 5460 |
DIRAS3,MBD5,VIRMA,CAV1,ARF6,RHOH,LGALS3,GJA1,HRAS,RAB35,RHOG,LAMTOR1,RHOB,LGALS8,DNAJC5,LAMP2,RAB2A,RAB5C,LRRC73,RAB11A,STX7,FLOT1,KRAS,RAB3B,ZNF365,RAB5A,RAB9A,RND3,OR10A4,RAB4A,RND2,CDC42 |
| 5.886e-03 | -5.14 | SNRNP40 (small nuclear ribonucleoprotein U5 subunit 40) | protein interactions | 9410 | 628 | 205 | 19454 | 5460 |
PHAX,MACROH2A1,SF3B6,UBN1,GCFC2,CSTF3,SRPK2,SUGP1,RPL7A,VAMP5,UBE2H,CDKN2AIP,RC3H2,NR0B1,ACP5,PML,WDR3,RBM22,SNRNP27,PPP1R8,HEXIM1,TFIP11,ACACA,LUC7L3,RPA2,ZNF326,AIP,DKC1,RBM42,SURF6,CDC5L,FZR1,COPS5,GAPDH,RBM17,CDK12,USP15,SNRNP70,RBM41,RPL3,DDR1,NOSIP,SNIP1,ZNF451,MEPCE,TNKS2,MNAT1,CDC40,TMSB10,ESS2,WBP11,IMP3,STRBP,NUPR1,SURF4,RP9,IK,GTF2F1,PHF21A,PHF12,MIDEAS,ATXN1L,ZCCHC7,SNRNP40,SNRPB,MYC,HNRNPAB,HNRNPC,RBBP8,CCT2,FTSJ3,SF3B1,DDX5,SLU7,SNRPA,EYA3,ZNF362,NCOA5,PRCC,RBM5,HMG20A,HNRNPL,TCP1,SNRPD3,SNRPA1,XPO1,DDX50,PFDN5,MAGOH,EWSR1,BCL9,CCT8,TOP2B,PFDN1,CCAR1,HNRNPDL,POLDIP3,CBLL1,ZNF609,KRAS,RUVBL1,NUDCD3,ELF1,TOP3B,TRMT1L,DHX38,SUPT5H,TRIM24,CCNF,PELP1,EIF4A3,TUBA1B,VIRMA,RPL13A,USP14,PPP1CC,KPNA6,MAPRE1,TADA3,KIN,HMCES,MTDH,TCEA1,PRIM2,RPA3,NCDN,PRPF4,AATF,SF3A1,WDR83,TXNL4A,RBFOX2,CCND1,SNRPN,HNRNPH3,LMNA,LSM2,MYBL2,ETV6,AKAP17A,CWC15,TOP1,MOV10,ECD,MPHOSPH10,TCOF1,NKRF,PQBP1,MDC1,SNRPG,TSSC4,CTNNBL1,LSM4,CD2BP2,MLLT6,CCT5,MSRB3,SNRPD2,SNRPD1,VPS72,RSRC1,MAD2L2,SNRPB2,PRPF31,MCM4,PFDN2,RIT1,PFDN6,BRCA1,LMNB1,YWHAZ,TXNL1,NMRAL1,NKAPD1,COIL,G3BP2,NOP53,MYL6,USP39,AGGF1,COPS2,RPL9,SRSF10,PRPF18,NOP58,CCAR2,HNRNPA1,ZNF207,PRPF19,HNRNPD,RSBN1L,ADAT1,DDX23,KDM2A,SRSF7,HNRNPA2B1,PPWD1,SSRP1,COPS4,DHX16,MAK16,RAF1,KHDC4,GPBP1L1,SNRPE |
| 5.905e-03 | -5.13 | negative regulation of chemotaxis | biological process | GO:0050922 | 51 | 24 | 18204 | 5365 |
NRP1,ST6GAL1,DUSP3,CCL2,MIR223,DUSP1,PADI2,MIR15A,MIR424,MIR34A,MIR16-1,TNFAIP6,CCN3,DDT,MIF,MMP28,STAP1,GREM1,AIF1,HDAC6,CXCL13,MIR149,DPP4,SEMA5A |
| 5.944e-03 | -5.13 | negative regulation of calcium ion transport | biological process | GO:0051926 | 70 | 31 | 18204 | 5365 |
MIR208A,MRLN,TLR9,PLN,PPP3CA,GSTM2,INPP5K,LILRB1,GSTO1,TMBIM6,VDAC1,MIR208B,ATP1A2,TRIM27,DRD3,PPP3R2,MIR200C,STC1,CLIC2,EPO,FKBP1A,PACSIN3,FKBP1B,MIR1-1,SESTD1,MIR34A,GPR35,MIR424,CAV3,CRHR1,SRI |
| 5.944e-03 | -5.13 | cellular response to unfolded protein | biological process | GO:0034620 | 70 | 31 | 18204 | 5365 |
EIF2S1,BAX,CDK5RAP3,OPTN,BAK1,DERL1,ERLEC1,VAPB,NFE2L2,RPAP2,OS9,PACRG,CCND1,ATF3,ATF4,HSPB8,CREB3,DDIT3,SELENOS,XBP1,CREBZF,HSPA5,DNAJC10,STUB1,DERL2,ERO1A,BAG3,PTPN1,HSPD1,EIF2AK2,TMBIM6 |
| 5.945e-03 | -5.13 | regulation of type II interferon production | biological process | GO:0032649 | 118 | 48 | 18204 | 5365 |
IRF8,IL23A,LTA,MIR708,TLR7,JAK2,NLRP6,LILRB4,INHA,PDCD1LG2,CYRIB,IL2,CCR2,TLR8,CEBPG,CD14,IL20RB,TLR9,CLEC7A,IL21,XCL1,IL12B,IL10,MIR24-1,TLR3,VSIR,TNF,CD47,CD2,TRIM27,DDIT3,TLR4,HRAS,PYCARD,PDE4B,CCR7,ISG15,PRNP,LILRB1,IL1B,IL12A,FOXP3,CD274,HSPD1,IL18,PTPN22,HMGB1,SASH3 |
| 5.961e-03 | -5.12 | Merkel_cell_carcinoma | COSMIC cancer mutations | Merkel_cell_carcinoma | 21 | 12 | 16828 | 4835 |
KRAS,HRAS,PTEN,PIK3CA,TERT,AKT1,NF2,JAK2,CTNNB1,KIT,RB1,TP53 |
| 5.961e-03 | -5.12 | haemangioma | COSMIC cancer mutations | haemangioma | 21 | 12 | 16828 | 4835 |
TP53,HRAS,KIT,KRAS,CTNNB1,IDH2,IDH1,AKT1,TERT,PIK3CA,EWSR1,PTEN |
| 5.961e-03 | -5.12 | oligodendroglioma | COSMIC cancer mutations | oligodendroglioma | 21 | 12 | 16828 | 4835 |
KRAS,IDH1,SMARCB1,PTEN,KIT,MET,CTNNB1,TP53,CDKN2C,NF2,NOTCH2,IDH2 |
| 5.961e-03 | -5.12 | central_nervous_system-brain-glioma-ependymoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma | 21 | 12 | 16828 | 4835 |
IDH1,TP53,CTNNB1,IDH2,FBXW7,AKT1,NF2,PTPN11,PIK3CA,TERT,SMARCB1,PTEN |
| 5.967e-03 | -5.12 | 3HCDH | prosite domains | PS00067 | 4 | 4 | 12186 | 3388 |
HADHA,HADH,CRYL1,EHHADH |
| 5.967e-03 | -5.12 | DOMON | prosite domains | PS50836 | 4 | 4 | 12186 | 3388 |
FRRS1L,FRRS1,MOXD1,DBH |
| 5.972e-03 | -5.12 | SLC25A31 (solute carrier family 25 member 31) | protein interactions | 83447 | 45 | 21 | 19454 | 5460 |
LPAR2,PSMB5,RABIF,MEPCE,ZDHHC17,TGFBR2,FGF12,SLC31A1,CFTR,DNAJB2,TASL,SCN3B,UPK1A,PPP4C,TBC1D17,HEXIM1,FBXL3,NGB,CHCHD4,ZC4H2,TFCP2 |
| 5.972e-03 | -5.12 | MXD1 (MAX dimerization protein 1) | protein interactions | 4084 | 45 | 21 | 19454 | 5460 |
SAP30L,E2F6,DISC1,MXD1,CBX3,SAP30,BRMS1,VDR,MAX,AKT1,MYC,CD2,RIGI,PCGF6,BRMS1L,PTEN,YAF2,RING1,BIRC2,PML,SIN3A |
| 5.972e-03 | -5.12 | SLC25A25 (solute carrier family 25 member 25) | protein interactions | 114789 | 45 | 21 | 19454 | 5460 |
VIPR1,SLC25A23,SLC1A1,AIFM1,CD79B,SYNCRIP,COX4I1,SFXN1,METAP2,APLNR,SLC25A12,PARL,CD80,SLC25A51,SLC15A1,APOO,MGARP,STK38L,KLK5,AQP3,PDCD1 |
| 5.972e-03 | -5.12 | TEP1 (telomerase associated protein 1) | protein interactions | 7011 | 45 | 21 | 19454 | 5460 |
TIRAP,H2BC9,ACTL6B,TOP3B,TP53,PRKCA,COP1,SMDT1,BRD3,TERT,MTDH,BAG2,CIB2,TRIM52,FTL,PTGES3,RIGI,VIRMA,SPPL3,HNRNPL,NOP53 |
| 5.976e-03 | -5.12 | TUB (TUB bipartite transcription factor) | protein interactions | 7275 | 29 | 15 | 19454 | 5460 |
RPF2,PIK3R1,MAK16,H2AX,TULP3,RBM34,ELAVL4,GNAQ,MYEF2,KRAS,NME4,GPC1,RORB,JAK2,SRC |
| 5.976e-03 | -5.12 | NRDE2 (NRDE-2, necessary for RNA interference, domain containing) | protein interactions | 55051 | 29 | 15 | 19454 | 5460 |
RPS10,STAU1,ESR2,VIRMA,ATP6AP2,VPS28,UQCC2,EED,RPA2,MED29,UBE2H,RAF1,ZNF32,ATG16L1,SPG21 |
| 5.976e-03 | -5.12 | CHRNE (cholinergic receptor nicotinic epsilon subunit) | protein interactions | 1145 | 29 | 15 | 19454 | 5460 |
DAG1,DIPK1A,TMUB2,CYB5R1,TMEM219,POMT2,ST3GAL4,TMEM30A,TMEM59L,NXPE3,LRP12,RBM3,ITGA6,PXYLP1,TUSC3 |
| 5.976e-03 | -5.12 | PLPP3 (phospholipid phosphatase 3) | protein interactions | 8613 | 29 | 15 | 19454 | 5460 |
LAMTOR1,SHC1,LAMP3,LAMP2,DPP4,RAB2A,RAB5C,STX7,CTNND1,CAV1,BCL6,ARF6,KRAS,PTEN,RAB35 |
| 5.976e-03 | -5.12 | PLEKHA6 (pleckstrin homology domain containing A6) | protein interactions | 22874 | 29 | 15 | 19454 | 5460 |
TCEAL9,ARMC8,UBE2H,FBP1,MYC,ZMYND19,MED9,XPO1,CTNNB1,CFTR,KRAS,KCTD9,PFDN1,ESR2,CTNNA1 |
| 5.997e-03 | -5.12 | IL1-mediated signaling events | Pathway Interaction DB | il1pathway | 35 | 20 | 2226 | 782 |
TAB1,TOLLIP,NFKB1,IKBKB,PIK3R1,PIK3CA,UBE2V1,IL1R2,MAP2K6,IRAK4,TRAF6,MAP3K3,SQSTM1,MYD88,TAB2,TICAM2,JUN,IL1A,UBE2N,IL1B |
| 6.010e-03 | -5.11 | DCAF6 (DDB1 and CUL4 associated factor 6) | protein interactions | 55827 | 213 | 77 | 19454 | 5460 |
UCK2,ADAMTS1,ACVR1,MAGEA4,MTA2,SUPT5H,CDK4,CCT5,ING1,NUDCD3,TRIM63,TTC4,MDC1,HS2ST1,PFDN1,EGR1,NAE1,NTRK2,PC,SRSF7,RING1,FKBP4,MSMB,AGR2,KPNA1,TNNC2,PFDN5,PMM2,BMPR1B,MDFI,MOV10,XPO1,TCP1,GRM1,SCG2,HNRNPL,CETN2,KLK3,PHB1,DUSP6,AIP,SRP14,COPS2,GTF2IRD1,JUP,CTBP1,ACACA,PIH1D1,UBE2M,UBE2D3,SRSF2,ATP6V1G1,VPS28,YAF2,NR2E1,PFDN6,KCNB1,PFDN2,SMAD2,PFDN4,SP1,COPS7A,PNOC,GMPS,PCCB,AR,MBL2,DAPK1,TXN,LYZL6,SMURF1,NFKBIA,DLG4,GRIA1,DDIT4,PLP1,GSK3A |
| 6.019e-03 | -5.11 | ATAD1 (ATPase family AAA domain containing 1) | protein interactions | 84896 | 79 | 33 | 19454 | 5460 |
EGLN3,MAD2L2,ZBTB2,SEC61B,RAC2,AIFM1,LMBR1L,METAP2,NRP1,FIS1,MARCHF3,LMNB1,RHOB,CGRRF1,NFKB1,BABAM1,RIGI,GOSR1,EMC1,VDAC1,NMRAL1,BSCL2,AKAP1,RAB9A,RPA3,NDUFA4,RPA2,RPN1,AQP3,FAF2,RND2,CDC42,TPT1 |
| 6.019e-03 | -5.11 | MBD4 (methyl-CpG binding domain 4, DNA glycosylase) | protein interactions | 8930 | 79 | 33 | 19454 | 5460 |
SIN3A,UBE2I,CSNK2B,TRIM27,PRNP,NAT2,ESR2,MOV10,RSPH1,MYC,NONO,SUV39H1,HNRNPA1,RPL26,PSMD1,FAS,RPL23,SERPINB1,HNRNPA2B1,DHX9,PRKCB,RPL4,TRIM63,GDPD3,KDM1A,H1-6,TFG,AZGP1,RPL28,RPL15,DDX39A,CRABP2,RWDD3 |
| 6.025e-03 | -5.11 | Signaling by PDGF | REACTOME pathways | R-HSA-186797 | 376 | 141 | 10285 | 3229 |
SPTBN1,PPP5C,AGO1,PDE1B,PSME1,ANGPT1,NCK1,PSMD7,FGF17,CD80,PSMD14,PTPN11,PRKACB,PRKCA,UBB,STAT5A,PPP2R1A,CREB1,PSMD3,JAK2,PSMB7,PIK3R1,CRKL,AHCYL1,PSMB1,PSMA3,PSMB5,ADCY3,CDKN1B,PSMC4,PSMA4,PSMB11,PSMC5,FGFR1,IL2,PSMB10,PSMA2,PSMB6,ADCY2,DLG4,CD28,CSK,SPP1,BRAP,FGF3,PSME2,PSMD6,THBS3,HBEGF,PSMB9,SPRED2,IL2RA,GSK3A,BAD,MAP3K11,DUSP10,NEFL,CDKN1A,PRKCE,PIK3R3,CSF2,JAK1,FGF7,PSMD12,AKT2,SHC3,RAP1A,STAT1,FRS3,PSMD10,SRC,DUSP9,MOV10,FGF10,PIK3AP1,RAP1B,MAP2K1,KRAS,FGF22,UBA52,WDR83,RAF1,TNRC6C,IL2RG,PIK3R2,ICOS,MDM2,PLG,YWHAB,DUSP6,FGF1,PPP2R5A,MET,PAQR3,FGF23,PTEN,PSMA5,SPTAN1,PDE1A,PPP2R5E,PIP5K1A,PEBP1,PSMB3,SHC1,RASGRP3,PSMB4,SEM1,DUSP1,PSMC3,TP53,CD86,PSMA1,RPS27A,IL3,PSMD4,PHB1,SPRED1,FGF16,IL2RB,FURIN,LAMTOR3,CAMK2G,VWF,IER3,CUL3,PSMC1,LAMTOR2,PPP2CB,KIT,STAT6,GAB1,HRAS,IL5,PIP4K2C,PSMD1,PSMB2,PIK3CA,PEA15,AKT1,AKT3,PSMA6 |
| 6.027e-03 | -5.11 | AXIN1 (axin 1) | protein interactions | 8312 | 154 | 58 | 19454 | 5460 |
ZBTB26,PNMA2,PRKAG1,TRAF2,EEF1A1,ANP32A,CSNK1E,TP53,TNKS2,CDCA7L,STX11,TRIM37,TRIM11,HNRNPA2B1,USP15,CRBN,XPO1,CTNNB1,MDFI,PPP2R5A,EGLN3,CAV1,TRIM15,TNKS,SMAD3,ETV6,RCHY1,PPP2CB,TFIP11,CSNK1A1,JUP,WSB1,H1-5,SUMO1,PIAS1,FXR2,SQSTM1,DVL2,PML,GID8,SMAD2,LRP6,SP1,CRMP1,MAPRE1,LAMTOR1,FBXW11,NTAQ1,ARHGAP21,LMO2,TNFAIP3,MYC,SMURF1,TRIM54,SIAH1,GSK3A,TRIM27,CTNNA1 |
| 6.027e-03 | -5.11 | CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase) | protein interactions | 10423 | 154 | 58 | 19454 | 5460 |
RPLP1,PHB1,SSMEM1,PTPN1,TLCD4,TMEM170A,ARF6,PCSK9,DDRGK1,FCGR2A,COPS5,RAB5C,DPP4,ATG9A,AQP2,PEX3,PDE2A,KRAS,GJB1,TP53,UBL4A,CAPZA2,RELL2,EZH2,SARM1,GPR173,RETREG3,CYB5R3,SMAP2,ELOVL4,PLP1,LMBR1L,CCNF,MAD2L2,ESR2,MGST3,SCN3B,UBE2H,ILK,RIT1,NTRK3,CYB561,CGRRF1,FCER1G,LAMTOR1,EXD2,JAGN1,TMX2,RPA3,COIL,YTHDF1,STAU1,SLC7A1,HSCB,ATP6V0E1,GRM2,RPA2,SDCBP |
| 6.027e-03 | -5.11 | Signalling to ERKs | REACTOME pathways | R-HSA-187687 | 263 | 102 | 10285 | 3229 |
SEM1,DUSP1,RASGRP3,SHC1,PSMB4,IL3,RPS27A,SPRED1,PSMD4,PHB1,PSMC3,PSMA1,VWF,PSMC1,CUL3,RALA,FGF16,CAMK2G,LAMTOR3,IL2RB,PSMD1,PSMB2,PEA15,PSMA6,IL5,HRAS,KIT,LAMTOR2,PPP2CB,FGF10,PSMD10,FRS3,DUSP9,SRC,WDR83,UBA52,FGF22,RIT1,RAF1,RAP1B,RALB,KRAS,MAP2K1,YWHAB,PPP2R5A,FGF1,DUSP6,IL2RG,PPP2R5E,SPTAN1,PSMB3,PEBP1,PAQR3,MET,PSMA5,FGF23,IL2RA,SPRED2,PSMB9,PSME2,FGF3,HBEGF,PSMD6,NEFL,DUSP10,MAP3K11,FGF7,JAK1,PSMD12,MAPKAPK3,CSF2,SHC3,RAP1A,FGF17,PSMD7,PPP5C,RIT2,SPTBN1,ANGPT1,PSME1,PPP2R1A,UBB,PSMD14,PSMB5,PSMA3,PSMC4,JAK2,PSMB7,PSMD3,PSMB1,CRKL,PSMB6,PSMA2,BRAP,CSK,DLG4,PSMA4,PSMB10,FGFR1,IL2,PSMC5,PSMB11 |
| 6.027e-03 | -5.11 | protein-containing complex disassembly | biological process | GO:0032984 | 153 | 60 | 18204 | 5365 |
BMERB1,HMGA1,APEH,ETF1,FAF2,VPS4A,CFL2,VAMP7,CHMP1A,SNX14,GFM2,MYC,LAMP2,VMP1,CHMP1B,VAMP8,H2BC1,MAP1LC3B,HSPA8,VPS33A,TRIM21,SMARCE1,CFL1,GABARAP,VPS4B,DDIT4,SNAP29,HDAC6,SMARCB1,CHMP2A,MCOLN1,H2AC25,TSG101,VTI1B,ABCE1,VIPAS39,SNAPIN,GABARAPL1,CCSAP,CHMP2B,MAP1LC3A,VPS16,LIX1,CHMP5,VTA1,GABARAPL2,SMARCD3,NFE2,SSRP1,PYM1,MTRF1,RPL23,KIF2A,BECN1,STMN2,TFIP11,CHMP4C,STX17,DSTN,NAPA |
| 6.038e-03 | -5.11 | human chr3q22.3 | chromosome location | human chr3q22.3 | 23 | 11 | 26134 | 5823 |
DBR1,PCCB,SLC35G2,NCK1,SOX14,MRAS,MSL2,IL20RB,ARMC8,FAIM,CEP70 |
| 6.042e-03 | -5.11 | activation of immune response | biological process | GO:0002253 | 368 | 131 | 18204 | 5365 |
HMGB1,CLU,SYK,MBL2,NLRP1,PTPN22,C1QC,OTULIN,NCR3,TLR6,HRAS,PYCARD,CREBBP,STK11,TRIM5,EP300,NFKBIA,TNF,CLPB,FCN2,CACNB3,KLRC2,TNFAIP3,PIK3AP1,EIF2B3,LY96,YES1,PHB1,CD2AP,CD38,NLRP3,TRAF6,TLR2,CD14,TICAM2,TLR10,BECN1,TIFA,PAK2,TLR5,XRCC5,TBK1,UBE2N,KLRD1,CRKL,TMEM126A,MAPKAPK3,CTLA4,LAT2,MAP2K6,LSM14A,PSPC1,TLR7,IRF7,NLRP6,TIRAP,LACC1,FOSL2,KCNJ8,CACNB4,NFKB1,PRKCE,PRKCB,CGAS,OAS1,TRAF3IP3,CD79B,PLPP4,FOXP3,SRC,CD274,BCL10,HSPD1,MATR3,PHB2,MICB,TOMM70,BTN2A2,HEXIM1,HSP90AA1,IRF3,THY1,NONO,PDE4B,RNF34,TLR4,STOML2,PIK3CA,FGR,TLR3,SPPL3,FCER1G,BAX,SPG21,CSK,CLEC7A,IFIH1,TLR9,CD3G,MYD88,SLA2,PQBP1,IRAK4,RGCC,IFI16,TLR8,LILRA2,CD46,LCP2,EIF2B5,CD247,PSEN1,NCR3LG1,TLR1,TYROBP,SIN3A,TICAM1,RIGI,RBCK1,CLEC6A,MAVS,IKBKB,VAV2,RC3H2,NMI,CD28,MEF2C,ITK,ATAT1,EIF2B2,MOG |
| 6.043e-03 | -5.11 | juvenile_xanthogranuloma | COSMIC cancer mutations | juvenile_xanthogranuloma | 14 | 9 | 16828 | 4835 |
IDH2,IDH1,AKT1,TP53,KRAS,KIT,PTEN,PIK3CA,MAP2K1 |
| 6.043e-03 | -5.11 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-juvenile_xanthogranuloma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-juvenile_xanthogranuloma | 14 | 9 | 16828 | 4835 |
PIK3CA,MAP2K1,PTEN,KRAS,KIT,TP53,AKT1,IDH1,IDH2 |
| 6.043e-03 | -5.11 | conventional | COSMIC cancer mutations | conventional | 14 | 9 | 16828 | 4835 |
TERT,PIK3CA,EWSR1,SMARCB1,TP53,HRAS,KRAS,IDH2,IDH1 |
| 6.049e-03 | -5.11 | BZIP | prosite domains | PS50217 | 51 | 23 | 12186 | 3388 |
TEF,NFIL3,NFE2,HLF,JUN,MAFG,CREB3L4,BATF,JUNB,ATF3,FOS,CEBPE,XBP1,CREB3,FOSL2,BACH1,NFE2L2,NFE2L1,ATF4,DDIT3,CEBPG,ATF1,CREB1 |
| 6.056e-03 | -5.11 | TRAF2 (TNF receptor associated factor 2) | protein interactions | 7186 | 592 | 194 | 19454 | 5460 |
AASDHPPT,PCSK9,HSP90AB1,SRSF1,CEP57L1,TNIK,CASP12,AGR2,IKBKB,CBL,SIVA1,SPATA2,TENM3,GAS8,SHC3,CHCHD2,EWSR1,SPG21,ISG15,TRAF2,APEX1,ESR2,APEX2,SCNM1,TNFRSF9,RRAS2,BEX3,MYC,THAP7,CXCL1,STAU1,FXR2,LYG2,DDI1,FAM50B,CD40,CXCL3,PCGF2,EP300,TIFA,IL15RA,PAK2,CSNK1A1,TANK,PSMB3,DUSP14,CAND1,SURF6,UBE2N,ITGA6,BECN1,BCL10,TNFRSF14,DNAJB2,XAF1,USP2,COPS5,RBCK1,CRYBA2,PSMA5,CDC40,TCEA2,ZBTB25,ERO1A,EFHC1,EDA2R,RBM41,MINDY3,TAB2,APOO,UBXN2B,DYRK1A,TRAF1,SMURF1,RPS3,MACROH2A1,ZNF655,ZFAND6,NIF3L1,CEP85,TNFAIP3,MLF1,RNASET2,TRIM32,GORASP2,BCL6,ZC3H15,PML,ARHGEF6,IRF3,RAB9A,HSPB2,RNF146,RPA2,GSTP1,SUMO1,CDC42,PRPF18,TRAF6,UBE2D1,RB1CC1,CDKN1B,NAB2,SIAH2,FATE1,MAP3K14,TRIM37,ZBTB16,TNF,ENKD1,GCA,MAP3K11,OSTM1,MOXD1,KIAA0408,JUN,TAB1,CD40LG,UBE2V2,SARM1,ZMAT2,YWHAZ,HTRA2,FAM107A,HSP90AA1,SLC7A11,CUL3,ZNF250,TTC23,RHEB,RNF40,NFIL3,TNFSF10,TNFSF12,NUP50,CRY1,BIRC2,TRUB1,KLF3,MFAP1,LNX2,DCUN1D1,PPP1R18,CAV1,CDK9,ETV6,PSMB1,CDCA3,MUL1,ZNF688,SMG9,SETD5,IRF4,HENMT1,FNDC11,ZMYND11,VRK1,TSSC4,RNF20,TICAM1,LTBR,GABPB1,ALPL,HINFP,TBK1,SOX9,UBE2V1,NECAP2,YES1,TXN,TNFRSF1B,EIF2AK2,STUB1,NUDT18,MSN,UBE2I,ATOSB,ASCC1,MAPRE1,BAHD1,CCHCR1,AP2A1,FBXO7,BRAP,TRAF3IP2,NTAQ1,FBXW7,UTP23,CHMP2B,DVL2,MAVS,SQSTM1,ZNF574,FAM161A |
| 6.078e-03 | -5.10 | parietal_lobe | COSMIC cancer mutations | parietal_lobe | 55 | 25 | 16828 | 4835 |
CFTR,MSH6,SF3B1,GNAQ,IDH2,AKT1,GNA11,CTNNB1,EZH2,SMARCB1,PIK3CA,IDH1,KRAS,CLCN6,FBXW7,PPP2R1A,NF2,CDKN2C,RBM23,TP53,NACC2,KIT,MET,PTEN,FGFR1 |
| 6.084e-03 | -5.10 | PPP1R3F (protein phosphatase 1 regulatory subunit 3F) | protein interactions | 89801 | 12 | 8 | 19454 | 5460 |
DDX39A,UBE3A,PPP1CC,DYRK1B,PYGB,DYRK1A,PTGER4,GPR35 |
| 6.084e-03 | -5.10 | BCL2L2-PABPN1 (BCL2L2-PABPN1 readthrough) | protein interactions | 100529063 | 12 | 8 | 19454 | 5460 |
USP2,PABPC1,PRR3,NTAQ1,RIMS3,FBXW7,RC3H2,RIT1 |
| 6.084e-03 | -5.10 | ADGRB3 (adhesion G protein-coupled receptor B3) | protein interactions | 577 | 12 | 8 | 19454 | 5460 |
C1QL3,OXCT1,GPR37L1,SLC7A1,ELMO1,SNTA1,TLCD4,C1QL2 |
| 6.084e-03 | -5.10 | STAB1 (stabilin 1) | protein interactions | 23166 | 12 | 8 | 19454 | 5460 |
CHID1,ORC5,NUFIP2,DYRK1A,CDC5L,SPPL3,RPN1,PIK3R2 |
| 6.084e-03 | -5.10 | ARMCX4 (armadillo repeat containing X-linked 4) | protein interactions | 100131755 | 12 | 8 | 19454 | 5460 |
EXD2,MTCH2,AIFM1,DPAGT1,AKAP1,PRKACB,RMDN3,FKBP8 |
| 6.084e-03 | -5.10 | PCTP (phosphatidylcholine transfer protein) | protein interactions | 58488 | 12 | 8 | 19454 | 5460 |
UBB,RAD23B,TPPP,RANGRF,ACOT13,RAB5A,RAP1A,AGTRAP |
| 6.084e-03 | -5.10 | SPDYC (speedy/RINGO cell cycle regulator family member C) | protein interactions | 387778 | 12 | 8 | 19454 | 5460 |
CDK1,CDKN1B,CKS2,PAX6,CKS1B,RBFOX3,ARPP19,FCF1 |
| 6.084e-03 | -5.10 | OSER1 (oxidative stress responsive serine rich 1) | protein interactions | 51526 | 12 | 8 | 19454 | 5460 |
GSTK1,PSMB3,TRMT13,XPO1,PSMB9,TSR3,RIGI,LACC1 |
| 6.084e-03 | -5.10 | SERF1B (small EDRK-rich factor 1B) | protein interactions | 728492 | 12 | 8 | 19454 | 5460 |
REEP4,ELOVL7,RNASEK,CRB3,TMEM14B,TMX2,ELOVL4,TIMMDC1 |
| 6.084e-03 | -5.10 | RSC1A1 (regulator of solute carriers 1) | protein interactions | 6248 | 12 | 8 | 19454 | 5460 |
HSPD1,SPP1,ODC1,DDI1,SOD2,RAD23B,VIRMA,LSM8 |
| 6.084e-03 | -5.10 | ORF17.5 (ORF17.5) | protein interactions | 4961482 | 12 | 8 | 19454 | 5460 |
GMDS,WWP1,OS9,KPNA1,IDE,WWP2,PRMT6,KPNA6 |
| 6.089e-03 | -5.10 | ACADS (acyl-CoA dehydrogenase short chain) | protein interactions | 35 | 19 | 11 | 19454 | 5460 |
CLIC4,SEPHS1,LYRM2,IRF7,STX5,GGT7,RING1,DPEP1,EZH2,SEC22C,ESS2 |
| 6.089e-03 | -5.10 | UQCC3 (ubiquinol-cytochrome c reductase complex assembly factor 3) | protein interactions | 790955 | 19 | 11 | 19454 | 5460 |
BPNT2,NDUFB10,CUL3,APOO,BORCS6,FZR1,RHOJ,RAMP3,ESR2,AIFM1,SFXN1 |
| 6.089e-03 | -5.10 | Ophn1 (oligophrenin 1) | protein interactions | 94190 | 19 | 11 | 19454 | 5460 |
LDHB,RBFOX2,TPM3,PPIF,GTF2IRD1,ATP5PO,RPN1,TMOD2,RBM22,PSMA1,PRDX4 |
| 6.089e-03 | -5.10 | vIRF-1 (K9) | protein interactions | 4961464 | 19 | 11 | 19454 | 5460 |
TFCP2,SDC2,CREBBP,IRF1,GPC4,IRF7,ENKD1,IRF3,UBP1,EP300,RB1 |
| 6.089e-03 | -5.10 | CCL14 (C-C motif chemokine ligand 14) | protein interactions | 6358 | 19 | 11 | 19454 | 5460 |
NOA1,CCR1,PIK3R1,CCL5,DDX39A,CCL11,EXOSC8,DNLZ,CCR3,AKT2,CCR5 |
| 6.089e-03 | -5.10 | MEFV (MEFV innate immunity regulator, pyrin) | protein interactions | 4210 | 19 | 11 | 19454 | 5460 |
BECN1,LGALS3,LGALS8,NLRP3,GABARAP,PYCARD,ATG16L1,SIVA1,GABARAPL2,MAP1LC3A,GABARAPL1 |
| 6.095e-03 | -5.10 | Brix | smart domains | SM00879 | 6 | 5 | 9717 | 2575 |
IMP4,BRIX1,RPF1,PPAN,RPF2 |
| 6.095e-03 | -5.10 | KOW | smart domains | SM00739 | 6 | 5 | 9717 | 2575 |
RPL26,RPL26L1,RPL27,MRPL24,SUPT5H |
| 6.103e-03 | -5.10 | regulation of sodium ion transport | biological process | GO:0002028 | 84 | 36 | 18204 | 5365 |
CAV3,FGF13,FXYD6,MIR448,AHCYL1,ATP1A1,PRKCE,SCN1B,ATP1B3,MIR192,PRSS8,PCSK9,SLMAP,SCN3B,ACTN4,MIR24-1,CHP1,NHERF1,ATP2B4,DLG1,FGF12,ADRB2,ATP1A2,ATP1B1,HECW1,TESC,SNTA1,NETO1,CNTN1,AKT1,SCN2B,RANGRF,MLLT6,CNKSR3,YWHAH,DMPK |
| 6.126e-03 | -5.10 | ADAM17 (ADAM metallopeptidase domain 17) | protein interactions | 6868 | 59 | 26 | 19454 | 5460 |
SDF2L1,CUL3,PDIA3,CX3CL1,MAD2L2,CCL17,MAD2L1,TNFRSF1B,SEC61B,EED,HSD17B11,DNASE1L1,NCR3,CFTR,CLEC2B,SEC62,TMEM106A,OTULINL,ST8SIA4,TNF,CAMK2G,CA10,TIMP3,DLG1,DERL1,LRRC3 |
| 6.126e-03 | -5.10 | HTATIP2 (HIV-1 Tat interactive protein 2) | protein interactions | 10553 | 59 | 26 | 19454 | 5460 |
MACROD1,REEP4,SSH3,RETREG3,HSD17B11,ACSL4,FITM2,TSNAX,LSM14B,HDAC6,RNF40,NFKB1,ASF1A,HNRNPK,RAB5A,TMX2,JAGN1,NCOA5,ABHD4,PRKCA,SH3GLB1,CAPZA2,TMEM115,CFTR,EHHADH,MIEF1 |
| 6.129e-03 | -5.09 | regulation of smooth muscle cell apoptotic process | biological process | GO:0034391 | 38 | 19 | 18204 | 5365 |
STUB1,PDE1A,MIR17,DIPK2A,IGF1,MIR28,IL12B,IFNG,LRP6,MIR24-1,IL12A,PPARG,MIR1-1,MIR210,PDCD4,MIR140,MIR21,SOD2,ATF4 |
| 6.129e-03 | -5.09 | regulation of T cell cytokine production | biological process | GO:0002724 | 38 | 19 | 18204 | 5365 |
IFNA2,CD81,LILRB4,IL6,TRAF2,B2M,RSAD2,CCR2,TRAF6,FOXP3,HFE,NLRP3,XCL1,IL4,IL1B,SASH3,TNFRSF1B,IL18,IFNB1 |
| 6.140e-03 | -5.09 | HIRIP3 (HIRA interacting protein 3) | protein interactions | 8479 | 82 | 34 | 19454 | 5460 |
UGP2,SSRP1,CLK1,RFC4,HIRA,FAF1,PPM1G,H2AX,ANP32A,CDK9,TMPO,SRC,SRPK2,STAT1,SNX2,CSNK2B,SEC23A,ARL4D,MACROH2A1,GTF2F1,RPL8,TNNC2,TSNAX,UBE2H,RPL24,H2AC4,XPO1,CSNK2A1,H2BC9,CFL2,OST4,PDIA3,CARS1,RIOX2 |
| 6.140e-03 | -5.09 | CCPG1 (cell cycle progression 1) | protein interactions | 9236 | 82 | 34 | 19454 | 5460 |
GABARAPL2,TMEM106A,DNAJC25,MAP1LC3B,GABARAPL1,SEC62,SSR1,RPN1,TMT1A,TMEM106B,SQSTM1,EGFL8,CST11,CLEC12B,TMED3,GABARAP,RIGI,DPM2,CLEC1A,ATG101,COPS5,AGR2,HFE,NTRK3,RB1CC1,SEC61B,ADAM21,MAP1LC3A,HSD17B11,PRNP,MANSC1,DNAJC1,SPPL3,DUOXA2 |
| 6.140e-03 | -5.09 | BLVRA (biliverdin reductase A) | protein interactions | 644 | 82 | 34 | 19454 | 5460 |
COPS5,AKT1,MYC,MARCHF5,CIART,SLC25A21,SNX5,DNAJB6,UBE2H,BLVRA,AIFM1,EZH1,PRNP,CGAS,DUSP1,MAP1LC3B,TUBA1A,PHF13,EZH2,RPA2,P2RY12,ACTR2,HSPA8,PRKCB,THBS3,EP300,RPA3,AKT2,RHOU,RNF26,DUSP19,HSCB,RRAGB,STAU1 |
| 6.156e-03 | -5.09 | CCDC22 (coiled-coil domain containing 22) | protein interactions | 28952 | 148 | 56 | 19454 | 5460 |
SAP18,SKP1,PACSIN3,CYFIP2,OIP5,MIA2,COMMD2,NUP50,RPA3,CNKSR3,UBE2M,SCLT1,RPA2,VIPAS39,COMMD3,BORCS6,NUP62,ATG16L1,NDE1,ARHGAP1,ACTB,GMDS,RTRAF,PSPC1,COMMD9,NONO,USP14,MYC,CUL2,CUL3,RTCB,ZYX,MTMR2,SH3GLB1,IFT57,STMN2,VPS33A,EXOC3,DISC1,KBTBD4,COMMD8,CPNE1,COMMD6,VPS26C,KRT8,RPRD1A,MED4,CAMSAP2,PSMG2,PSMD7,COMMD5,INSYN1,ATG7,PRDX1,CDC26,NDC80 |
| 6.156e-03 | -5.09 | KAT7 (lysine acetyltransferase 7) | protein interactions | 11143 | 148 | 56 | 19454 | 5460 |
LURAP1,CSNK2B,CALML5,APEX1,VIRMA,LRIF1,SFN,MYC,RGL2,OST4,CTSD,AR,CEP70,GMNN,RIT1,RPA3,JADE1,SAT1,NUCKS1,OIP5,FBXW7,COIL,ING5,CCL3,MAP2K1,RPA2,ACACA,H2AZ1,CCAR2,MEAF6,RPS10,ZBTB2,TMPO,DPY30,HMGA1,IFI16,CSNK2A1,XPO1,H2AC4,POLB,H2BC17,BRD3,POU5F1,G3BP1,DYNC1I1,H3C1,SSRP1,TP53,CSNK1E,SNAPIN,JUN,NECAP1,PPID,CAAP1,EZH2,NUPR1 |
| 6.156e-03 | -5.09 | GNL3L (G protein nucleolar 3 like) | protein interactions | 54552 | 148 | 56 | 19454 | 5460 |
OLA1,KRAS,RPS24,SRSF7,RPL31,OTULIN,SRP72,SKA3,ANAPC13,MGARP,PPP2R1A,TP53,CHMP2A,ZBTB2,MDM2,NOP58,HNRNPL,CDK12,KPNA1,DDRGK1,FAM174A,LAMP2,POLR1H,LDOC1,FTSJ1,ADRB2,TRA2B,TERT,RPA3,TFIP11,CTBP1,UBL3,PAFAH1B1,TOR1AIP2,RPL27A,ESR2,RPL10,APEX1,CSTF3,APLNR,FBXO22,DYNLL1,TRIM54,PSMD4,ZMAT5,VPS72,ZNF330,CCNF,S100A6,LMBR1L,UBE2H,BRCA1,FTSJ3,RHOB,CUL3,MYC |
| 6.167e-03 | -5.09 | positive regulation of mitotic cell cycle phase transition | biological process | GO:1901992 | 101 | 42 | 18204 | 5365 |
MEPCE,DTL,SIN3A,MDM2,CDC23,UBE2E2,CDC16,ANAPC11,RRM1,WNT10B,MAD2L1BP,FGF10,TMOD3,TERT,ADAMTS1,CDC20,MIR29A,CCND3,RB1,RAB11A,PLCB1,MIR495,SMARCD3,MIR208A,CUL3,CDC7,MIR214,AKT1,CDK1,RGCC,MIR222,LSM10,MTA3,CCND1,PHB2,VPS4B,AIF1,MIR221,CCNB1,CYP1A1,MIR519D,CDK4 |
| 6.167e-03 | -5.09 | negative regulation of monoatomic ion transmembrane transport | biological process | GO:0034766 | 101 | 42 | 18204 | 5365 |
MIR24-1,ISCU,PCSK9,MIR192,PPP3R2,MIR200C,FKBP1A,EPO,KCNAB1,CLIC2,CAV1,MIR448,GPR35,MMP9,SUMO1,SRI,CRHR1,CAV3,FKBP1B,TCAF2,PRKCE,MIR1-1,SESTD1,GSTM2,VDAC1,TMBIM6,GSTO1,TLR9,MIR208A,MIR30D,PPP3CA,PLN,ATP1A2,PPIF,DRD3,MIR153-1,OXSR1,MIR208B,CRBN,CAB39,HECW1,MIR212 |
| 6.177e-03 | -5.09 | fatty acid metabolic process | biological process | GO:0006631 | 322 | 116 | 18204 | 5365 |
PTGES3,MIF,NDUFAB1,COMT,MORC2,SCD5,ACSS2,MBLAC2,AIG1,ACADSB,PPARA,CYP2F1,LEP,HSD17B8,ELOVL3,CYP4F8,ACSL4,FADS2,MMUT,HACD2,HADHA,ACBD7,CYGB,LYPLA2,PEDS1,ABHD6,ACAA2,DECR2,PLA2G4B,PTGES,AUH,GNPAT,ADIPOR2,DEGS1,PCK2,CYP2D6,GSTA1,SESN2,HACD3,ABHD12,BRCA1,ELOVL4,EPHX1,LIPA,ACOX1,PPARG,ETFA,NUDT7,HADH,ABHD2,AKR1C2,PTGDS,AKR1C1,CYP4V2,ETFB,ELOVL7,HACD1,CRAT,PHYH,NUDT19,CD36,PNPLA8,CYP2C18,SLC25A17,PRKAG1,MGST3,LYPLA1,ACOT6,CYP4F12,MSMO1,GSTM2,AMACR,PEX13,PLA2G15,HACD4,AKR1B1,ABHD5,PCCB,ADTRP,ADIPOR1,MCAT,ADIPOQ,CRYL1,HSD17B10,GPAM,GSTP1,PRKAB1,LIAS,CPT2,GPX1,ACADS,CPT1B,FA2H,GSTM4,EHHADH,XBP1,GPX4,TECR,CYP1B1,PLAA,MECR,ACAT1,CYP1A1,CYP2C8,ACOT8,CBR4,CYP2C9,ELOVL6,HPGDS,ILVBL,PLA2G5,PLP1,ECHDC1,ALOX5AP,ELOVL1,ACACA |
| 6.183e-03 | -5.09 | suppression of viral release by host | biological process | GO:0044790 | 16 | 10 | 18204 | 5365 |
TRIM21,PML,TRIM26,TRIM5,TRIM35,TRIM15,TRIM8,TRIM27,TRIM32,TRIM11 |
| 6.183e-03 | -5.09 | cellular response to misfolded protein | biological process | GO:0071218 | 16 | 10 | 18204 | 5365 |
UFD1,HDAC6,CAV1,CUL3,STUB1,UBE2W,DERL1,SDF2L1,KLHL15,RNF126 |
| 6.183e-03 | -5.09 | cellular response to prostaglandin E stimulus | biological process | GO:0071380 | 16 | 10 | 18204 | 5365 |
PTGER4,AKT1,GNG2,ACACA,P2RY4,PTGER2,SFRP1,PRKCE,PAX6,GNB1 |
| 6.194e-03 | -5.08 | autonomic_ganglia-paraspinal-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-paraspinal-neuroblastoma | 26 | 14 | 16828 | 4835 |
GNAQ,MAP2K1,KRAS,HRAS,IDH1,PIK3R1,PIK3CA,CTNNB1,KIT,MET,AKT1,JAK2,PTPN11,IDH2 |
| 6.194e-03 | -5.08 | breast-hyperplasia-atypical_lobular_hyperplasia | COSMIC cancer mutations | breast-hyperplasia-atypical_lobular_hyperplasia | 26 | 14 | 16828 | 4835 |
KRAS,HRAS,MAP2K1,GNAQ,FBXW7,AKT1,JAK2,PTPN11,TP53,CTNNB1,KIT,MET,PIK3CA,FGFR1 |
| 6.194e-03 | -5.08 | autonomic_ganglia-mediastinum-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-mediastinum-neuroblastoma | 26 | 14 | 16828 | 4835 |
PIK3CA,JAK2,PTPN11,AKT1,IDH2,MET,KIT,CTNNB1,GNAQ,MAP2K1,PIK3R1,IDH1,HRAS,KRAS |
| 6.194e-03 | -5.08 | biliary_tract-gallbladder-carcinoma-adenosquamous_carcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-adenosquamous_carcinoma | 26 | 14 | 16828 | 4835 |
GNAQ,MAP2K1,KRAS,HRAS,FGFR1,PIK3CA,AKT1,JAK2,PTPN11,FBXW7,CTNNB1,MET,KIT,TP53 |
| 6.194e-03 | -5.08 | soft_tissue-blood_vessel-glomus_tumour | COSMIC cancer mutations | soft_tissue-blood_vessel-glomus_tumour | 26 | 14 | 16828 | 4835 |
GNAQ,MAP2K1,HRAS,KRAS,FGFR1,PIK3CA,PTPN11,JAK2,AKT1,FBXW7,KIT,MET,CTNNB1,TP53 |
| 6.194e-03 | -5.08 | glomus_tumour | COSMIC cancer mutations | glomus_tumour | 26 | 14 | 16828 | 4835 |
HRAS,KRAS,MAP2K1,GNAQ,FBXW7,PTPN11,JAK2,AKT1,TP53,KIT,MET,CTNNB1,PIK3CA,FGFR1 |
| 6.194e-03 | -5.08 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle | 26 | 14 | 16828 | 4835 |
MAP2K1,GNAQ,HRAS,KRAS,TERT,PIK3CA,PTEN,SMARCB1,TP53,KIT,RB1,CTNNB1,FBXW7,AKT1 |
| 6.194e-03 | -5.08 | paraspinal | COSMIC cancer mutations | paraspinal | 26 | 14 | 16828 | 4835 |
PIK3CA,CTNNB1,KIT,MET,AKT1,PTPN11,JAK2,IDH2,GNAQ,MAP2K1,KRAS,HRAS,IDH1,PIK3R1 |
| 6.194e-03 | -5.08 | adenosquamous_carcinoma | COSMIC cancer mutations | adenosquamous_carcinoma | 26 | 14 | 16828 | 4835 |
TP53,KIT,MET,CTNNB1,FBXW7,PTPN11,JAK2,AKT1,PIK3CA,FGFR1,HRAS,KRAS,MAP2K1,GNAQ |
| 6.194e-03 | -5.08 | atypical_lobular_hyperplasia | COSMIC cancer mutations | atypical_lobular_hyperplasia | 26 | 14 | 16828 | 4835 |
PIK3CA,FGFR1,FBXW7,AKT1,JAK2,PTPN11,TP53,CTNNB1,KIT,MET,MAP2K1,GNAQ,KRAS,HRAS |
| 6.194e-03 | -5.08 | autonomic_ganglia-abdomen-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-abdomen-neuroblastoma | 26 | 14 | 16828 | 4835 |
HRAS,KRAS,PIK3R1,IDH1,GNAQ,MAP2K1,KIT,MET,CTNNB1,JAK2,PTPN11,AKT1,IDH2,PIK3CA |
| 6.200e-03 | -5.08 | NBPF20 (NBPF member 20) | protein interactions | 100288142 | 4 | 4 | 19454 | 5460 |
RIT1,ESR2,SNIP1,KRAS |
| 6.200e-03 | -5.08 | MRGPRX1 (MAS related GPR family member X1) | protein interactions | 259249 | 4 | 4 | 19454 | 5460 |
GNB1,GNAI2,GNAQ,GNG2 |
| 6.200e-03 | -5.08 | Pax6 (paired box 6) | protein interactions | 18508 | 4 | 4 | 19454 | 5460 |
HOMER3,DYNLL1,TRIM11,PAX6 |
| 6.200e-03 | -5.08 | STYXL2 (serine/threonine/tyrosine interacting like 2) | protein interactions | 92235 | 4 | 4 | 19454 | 5460 |
YPEL5,MSX2,UFL1,PGRMC1 |
| 6.200e-03 | -5.08 | SCN9A (sodium voltage-gated channel alpha subunit 9) | protein interactions | 6335 | 4 | 4 | 19454 | 5460 |
CRELD1,CSK,TRIM37,FBXO22 |
| 6.200e-03 | -5.08 | GPX2 (glutathione peroxidase 2) | protein interactions | 2877 | 4 | 4 | 19454 | 5460 |
MYC,PSMB2,GPX2,TP53 |
| 6.200e-03 | -5.08 | ST6GALNAC2 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2) | protein interactions | 10610 | 4 | 4 | 19454 | 5460 |
DDX39A,SMAD3,CSK,SPPL3 |
| 6.200e-03 | -5.08 | SLC44A3 (solute carrier family 44 member 3) | protein interactions | 126969 | 4 | 4 | 19454 | 5460 |
RNF181,ABHD5,IMPA2,FHL3 |
| 6.200e-03 | -5.08 | Il6st (interleukin 6 signal transducer) | protein interactions | 16195 | 4 | 4 | 19454 | 5460 |
CBL,JAK1,SOCS3,PTPN11 |
| 6.200e-03 | -5.08 | Trim35 (tripartite motif-containing 35) | protein interactions | 66854 | 4 | 4 | 19454 | 5460 |
SMAD4,SMAD3,SMURF1,SMAD2 |
| 6.200e-03 | -5.08 | RPL37AP8 (ribosomal protein L37a pseudogene 8) | protein interactions | 644338 | 4 | 4 | 19454 | 5460 |
TRIM37,CCNF,PDIA6,MEPCE |
| 6.200e-03 | -5.08 | h3c8.S (H3 clustered histone 8 S homeolog) | protein interactions | 399088 | 4 | 4 | 19454 | 5460 |
ASF1A,BANF1,RBBP4,USP16 |
| 6.200e-03 | -5.08 | ZNF585A (zinc finger protein 585A) | protein interactions | 199704 | 4 | 4 | 19454 | 5460 |
CBX5,TOP3B,CUL3,CHTOP |
| 6.200e-03 | -5.08 | CALHM5 (calcium homeostasis modulator family member 5) | protein interactions | 254228 | 4 | 4 | 19454 | 5460 |
CFTR,ST7,CDK6,LRP10 |
| 6.200e-03 | -5.08 | Hspa4 (heat shock protein 4) | protein interactions | 15525 | 4 | 4 | 19454 | 5460 |
PTEN,SOD1,H3C1,CCNF |
| 6.200e-03 | -5.08 | Traf6 (TNF receptor-associated factor 6) | protein interactions | 22034 | 4 | 4 | 19454 | 5460 |
UBE2N,UBE2D3,UBE2V1,MAP3K14 |
| 6.200e-03 | -5.08 | CCDC3 (coiled-coil domain containing 3) | protein interactions | 83643 | 4 | 4 | 19454 | 5460 |
MDM2,TP53,PSMC4,TOP3B |
| 6.200e-03 | -5.08 | Pias2 (protein inhibitor of activated STAT 2) | protein interactions | 17344 | 4 | 4 | 19454 | 5460 |
DHX9,GTF2IRD1,GTF2I,HDAC3 |
| 6.200e-03 | -5.08 | ABCB4 (ATP binding cassette subfamily B member 4) | protein interactions | 5244 | 4 | 4 | 19454 | 5460 |
HAX1,DDX39A,TESK1,PIGY |
| 6.200e-03 | -5.08 | Senp1 (SUMO1/sentrin specific peptidase 1) | protein interactions | 223870 | 4 | 4 | 19454 | 5460 |
CCNF,SUMO2,SUMO1,SUMO3 |
| 6.200e-03 | -5.08 | CTNS (cystinosin, lysosomal cystine transporter) | protein interactions | 1497 | 4 | 4 | 19454 | 5460 |
GNMT,RIGI,KRAS,SPPL3 |
| 6.200e-03 | -5.08 | RGS22 (regulator of G protein signaling 22) | protein interactions | 26166 | 4 | 4 | 19454 | 5460 |
PSMD14,STAU1,PDIA6,FBXO7 |
| 6.200e-03 | -5.08 | Pick1 (protein interacting with PRKCA 1) | protein interactions | 84591 | 4 | 4 | 19454 | 5460 |
GPR37,PRKCA,GRIA2,BTG2 |
| 6.217e-03 | -5.08 | SERPINB5 (serpin family B member 5) | protein interactions | 5268 | 145 | 55 | 19454 | 5460 |
FBXL4,HSPA5,PYM1,SOD1,DDX46,HSPA8,JADE1,PRDX6,MMP14,STX17,LACC1,SF3A1,TANK,FTH1,SNX3,CALML5,EIF2S2,RAB9B,GLOD4,HSP90AA1,STK11,COL1A2,MDH1,AKT1,CTSD,NAA50,SFN,HMGCS1,KRAS,REXO2,VRK1,FBXO3,ZYX,TRIM21,ZC3H11A,ZRANB2,KHDC4,PPIL3,EEF1A1,SOX2,PPIF,ISG15,FCF1,CPLX3,CGAS,HSP90AB1,RAB11B,CBFB,FBXO32,ACTA2,GSTO1,SMAD4,GSTM3,PFDN5,PTDSS1 |
| 6.217e-03 | -5.08 | DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2) | protein interactions | 1783 | 145 | 55 | 19454 | 5460 |
RPS23,JPT2,TUBB4B,RPS7,ACTR1A,RPSA,ARFGAP1,DYNC1I1,HNRNPA2B1,PALM2AKAP2,TSNAX,FKBP4,WDR11,BTF3L4,NFKB1,CDC5L,DYNC1I2,C2CD2,CORO1C,PCBP4,ARL10,TNIK,CSNK1A1,EIF4B,RPA2,CFTR,PAFAH1B1,ARHGAP1,HSCB,MAVS,SQSTM1,SEPTIN6,RPA3,DDX39B,BAP1,UBE2H,MAPRE1,RPS26,NRP1,RPS5,BICD2,CUL3,RAB11A,CIAO1,MYC,ESR2,PSMB6,DYNLT3,DYNLL1,RPP25L,CEP41,RPS20,DLST,EFHD2,EIF3K |
| 6.219e-03 | -5.08 | FBXL14 (F-box and leucine rich repeat protein 14) | protein interactions | 144699 | 37 | 18 | 19454 | 5460 |
FEM1A,DICER1,STK11,HSP90AA1,DAAM1,TLE1,COPS7A,TOP3B,COPS5,SPCS1,TTC9C,DAPK1,SKP1,VIRMA,FSTL1,COPS2,SEC11A,SPCS2 |
| 6.219e-03 | -5.08 | TUBA3E (tubulin alpha 3e) | protein interactions | 112714 | 37 | 18 | 19454 | 5460 |
FHL3,AIFM1,MEPCE,NMI,CCT7,TCP11L2,CD81,LGR4,UBL4A,MYC,PFDN5,PFDN2,HEXIM1,PFDN4,PFDN6,CCT2,TFCP2,CHMP4C |
| 6.219e-03 | -5.08 | CYP4F2 (cytochrome P450 family 4 subfamily F member 2) | protein interactions | 8529 | 37 | 18 | 19454 | 5460 |
TLCD4,CYP4F12,LEPROTL1,MMD,REEP4,DNAJC1,SLC19A3,SDHAF2,UBE2I,RETREG3,ELOVL4,JAGN1,TMX2,FCER1G,PLEKHO1,SCN3B,CREB3,TM4SF19 |
| 6.219e-03 | -5.08 | KLHL36 (kelch like family member 36) | protein interactions | 79786 | 37 | 18 | 19454 | 5460 |
ITM2A,RNF41,APEX1,VIRMA,SPPL3,INA,TRIM63,HMGN4,HSPA8,HSP90AA1,PACRG,PDAP1,DNAJC27,CD2BP2,COPS5,UBXN2B,TOP3B,CUL3 |
| 6.219e-03 | -5.08 | LDHAL6A (lactate dehydrogenase A like 6A) | protein interactions | 160287 | 37 | 18 | 19454 | 5460 |
SUCLG2,ARF4,ETFA,LDHA,DSTN,UBE2N,ARF1,SOD1,PEBP1,SORD,MDH1,PDHA1,CFTR,CFL2,CFL1,RAB5C,CTSD,MYC |
| 6.219e-03 | -5.08 | Cdc20 (cell division cycle 20) | protein interactions | 107995 | 37 | 18 | 19454 | 5460 |
ANAPC2,ANAPC16,CCT8,CCT7,IREB2,MAD2L1,CDC20,BUB3,CCNA2,GKAP1,ANAPC13,CCT5,CDC26,GBE1,CDC16,ANAPC4,CDC23,CCT2 |
| 6.219e-03 | -5.08 | TMCC3 (transmembrane and coiled-coil domain family 3) | protein interactions | 57458 | 37 | 18 | 19454 | 5460 |
CYB5B,YWHAB,YWHAZ,VPS33A,STIM1,YWHAH,YWHAG,SFN,CUL2,VIRMA,HSBP1,RIGI,TMPO,DNAJC1,SEC61B,ENO1,SNIP1,PTPN1 |
| 6.219e-03 | -5.08 | ABHD17A (abhydrolase domain containing 17A, depalmitoylase) | protein interactions | 81926 | 37 | 18 | 19454 | 5460 |
APLNR,SRC,VPS28,RIGI,TRAF1,TCP1,TRIM27,BIRC2,HSPA8,PNMA1,DLG4,CCT2,TUBA1A,GPC4,LPAR6,HPGDS,MDFI,PLSCR4 |
| 6.219e-03 | -5.08 | ATG4C (autophagy related 4C cysteine peptidase) | protein interactions | 84938 | 37 | 18 | 19454 | 5460 |
PSMC5,TRAF7,ARF6,WASL,PSMC1,CLCN6,GABARAP,LAMP2,PSMC4,MAP1LC3B,LAMP3,GABARAPL1,KLHL22,VPS33A,LAMTOR1,PIP4K2C,GSTA2,SMG9 |
| 6.219e-03 | -5.08 | RASSF3 (Ras association domain family member 3) | protein interactions | 283349 | 37 | 18 | 19454 | 5460 |
MAP1B,SIKE1,MOB4,KDM1A,HNRNPL,LITAF,MDM2,SLMAP,STK3,FGFR1OP2,MAP1S,XPO1,STK4,TFRC,RPRD1B,VAPB,FBXW11,TENT5D |
| 6.244e-03 | -5.08 | KLHDC3 (kelch domain containing 3) | protein interactions | 116138 | 85 | 35 | 19454 | 5460 |
RPS6KA4,CHCHD4,ELOC,SUV39H1,BRAP,XPO1,COPS5,CUL2,MOV10,TSPYL4,RPP25L,COPS7B,DAPK3,COPS2,FBLN5,ENO1,POP7,UBE2M,RPL15,NUDCD3,PIP5K1A,DLG3,VDR,CSNK1E,G3BP2,FTL,COIL,TRIM52,WDR55,SLC31A1,NEDD8,RNF113A,HMCES,RTKN,THOC3 |
| 6.244e-03 | -5.08 | C1orf198 (chromosome 1 open reading frame 198) | protein interactions | 84886 | 85 | 35 | 19454 | 5460 |
XPO1,FAS,BPNT2,BICD2,MAPRE1,REP15,ENO1,GATD3,CTSB,TXNDC12,ARMC6,ACTB,APEX1,CAV1,CLIC4,TOMM22,DAAM1,ACTR1A,GLRX5,CDC42,NCSTN,STIM1,FGFR1,SCLT1,INPPL1,ZYX,PML,HINT2,EWSR1,HAPSTR1,AKAP1,SQSTM1,HINT1,TOMM20,MPST |
| 6.247e-03 | -5.08 | endosomal transport | biological process | GO:0016197 | 261 | 96 | 18204 | 5365 |
TMEM50B,PREPL,BLOC1S2,STX5,VPS4A,EHD1,GOSR1,CHMP1A,TOM1,TMCC1,RAB8B,STX10,SURF4,CALY,CHMP1B,ARHGAP1,VPS26B,RAB9A,TMEM87A,SQSTM1,TRIM27,SNAP25,STX8,SNX2,CHMP2A,SNX17,VTI1B,CHMP2B,AGAP2,STX12,SNX3,RHOBTB3,CHMP5,LEPROTL1,ACAP2,SNX1,EMP2,CCDC22,RGP1,BET1L,ANKRD50,EHD4,CHMP4C,SNX18,NSG1,TMEM50A,SNX5,DPY30,UBAP1,YKT6,RAB6B,RAB11A,VPS26C,RAB29,PHETA2,VPS28,RAB11B,RAB14,RAB6A,CORO1C,CMTM6,VPS39,TMED9,STX16,UBXN6,VPS4B,AP5S1,VPS26A,SNX33,EHD3,TSG101,TBC1D10C,SLC66A2,RNF126,HGS,PLEKHJ1,AP5M1,RAB5A,TRAPPC10,VPS16,TBC1D5,LMAN1,LAMTOR1,VTA1,FHIP1B,STX6,TBC1D17,RAB9B,SNX12,PICALM,RAB13,ARF6,RAB35,BECN1,VPS54,VAMP3 |
| 6.254e-03 | -5.07 | KAT2B (lysine acetyltransferase 2B) | protein interactions | 8850 | 248 | 88 | 19454 | 5460 |
IRF2,PNMA1,ALB,PTEN,PLAGL1,ACTB,DEK,AKT1,CREBBP,MYC,NFYA,TAF5L,ATF4,RAB11A,IRF1,AR,TADA3,SMAD2,SP1,TADA1,SERPINH1,H1-1,MAPRE1,SIRT7,SERTAD2,EP300,DR1,IRF7,HDAC3,SGF29,UBE2D3,ZBTB5,H1-5,CCND1,NFYB,SUPT3H,XBP1,CCNA2,CDKN1A,KLF12,KLF3,LMNA,PPARG,CTBP1,MED23,SUPT7L,SMAD3,NKX3-1,MCL1,RB1,PGR,FZR1,CCAR2,MDM2,HMGA1,ENY2,SAT2,CSNK2A1,CTNNB1,SIAH2,UBE2D1,MED21,H2AC4,SMAD9,HNRNPD,TAF9,CDKN1B,KLF10,SERTAD1,H3C1,SATB1,NFE2,TP53,JUN,ING1,EGR2,CCDC134,H2AX,ELF1,SMAD1,IKZF5,WDR37,EZH2,CDK8,SF3B5,SMARCB1,RBPJ,TAF10 |
| 6.257e-03 | -5.07 | translation factor activity, RNA binding | molecular function | GO:0008135 | 83 | 36 | 18094 | 5411 |
EIF5B,GTPBP1,EIF3G,ABCF1,GFM2,EIF3D,EEF2,EIF2S2,TUFM,EIF5A2,EIF4A2,EEF1B2,EIF1B,EIF2S1,EEF1G,CPEB1,COPS5,EIF1AX,EIF4B,EIF2B2,MTRF1,EIF3K,EIF3J,EIF2B3,EIF2D,EIF3E,EIF4E3,EIF2B5,GFM1,EIF4E2,EIF4H,EIF4E,GTPBP2,ETF1,EIF1AD,EEF1A1 |
| 6.257e-03 | -5.07 | ASB17 (ankyrin repeat and SOCS box containing 17) | protein interactions | 127247 | 24 | 13 | 19454 | 5460 |
RPL23,HSPB1,HSP90AA1,TRAF6,TUBB4B,TUFM,SLC25A1,ARF4,PHB2,VDAC1,TUBB,TUBA1B,NFKBIA |
| 6.257e-03 | -5.07 | PHACTR2 (phosphatase and actin regulator 2) | protein interactions | 9749 | 24 | 13 | 19454 | 5460 |
APEX1,VIRMA,KRAS,TMOD3,ACTB,ACTA2,RHOB,RNF40,YWHAG,YWHAH,H2BC9,BCL7C,PRPF19 |
| 6.257e-03 | -5.07 | AVEN (apoptosis and caspase activation inhibitor) | protein interactions | 57099 | 24 | 13 | 19454 | 5460 |
PSPC1,RPL10,SMURF1,STAU1,RPS16,ANAPC15,XPO1,RAF1,MOV10,BCL2L1,DRG1,BRCA1,BICD2 |
| 6.257e-03 | -5.07 | KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) | protein interactions | 3778 | 24 | 13 | 19454 | 5460 |
HNRNPL,SKP1,CAV1,KCNMB1,ACTA2,ALB,EED,KCNMA1,CRBN,CAV2,HMOX2,CAV3,FBXO7 |
| 6.257e-03 | -5.07 | COA4 (cytochrome c oxidase assembly factor 4 homolog) | protein interactions | 51287 | 24 | 13 | 19454 | 5460 |
AK2,LYPLA1,AK3,CDC42,NDUFAF3,COX11,TXNDC12,SH3BGRL,PTRHD1,PEBP1,CYB5R3,COX17,FAHD1 |
| 6.257e-03 | -5.07 | ICA1 (islet cell autoantigen 1) | protein interactions | 3382 | 24 | 13 | 19454 | 5460 |
SELENOT,PICK1,CLPB,MKKS,PRNP,MBD3,RAB2A,MORF4L1,ING5,EXOC5,WWP1,RNF181,STK16 |
| 6.257e-03 | -5.07 | MMP26 (matrix metallopeptidase 26) | protein interactions | 56547 | 24 | 13 | 19454 | 5460 |
ERRFI1,SERPINA1,SLC25A20,PDF,MMP9,ADGRL3,HAPSTR1,LAMB2,NME4,EPHA4,RAD21,UQCC3,PPP1R10 |
| 6.257e-03 | -5.07 | ZMAT3 (zinc finger matrin-type 3) | protein interactions | 64393 | 24 | 13 | 19454 | 5460 |
DICER1,EZH2,SAMHD1,SF3A1,SUMO2,STAU1,SIAH1,PRKRA,DHX9,EMC2,CNOT6,HNRNPA2B1,ACTA2 |
| 6.257e-03 | -5.07 | GSTO2 (glutathione S-transferase omega 2) | protein interactions | 119391 | 24 | 13 | 19454 | 5460 |
CNDP2,GSTO2,FKBP1A,GSTO1,NTAQ1,PFDN5,CREBBP,RBM12,GCA,TXN,TAGLN2,HINT1,GPX4 |
| 6.257e-03 | -5.07 | ZNF335 (zinc finger protein 335) | protein interactions | 63925 | 24 | 13 | 19454 | 5460 |
CCAR2,PRNP,CCR4,KRR1,PHF12,GATAD1,CDK6,HSPB2,RPL3,NOTCH2,RPSA,CDK4,TOP3B |
| 6.257e-03 | -5.07 | UBE2F (ubiquitin conjugating enzyme E2 F (putative)) | protein interactions | 140739 | 24 | 13 | 19454 | 5460 |
KRAS,DCUN1D1,PAX6,UBA3,NAE1,PMAIP1,RNF34,S100A11,RNF7,RIT1,DCUN1D5,PRDX1,DCUN1D3 |
| 6.287e-03 | -5.07 | monocarboxylic acid metabolic process | biological process | GO:0032787 | 518 | 179 | 18204 | 5365 |
PGM1,CYGB,ACBD7,PEDS1,LYPLA2,DECR2,CYP39A1,GNPAT,ELOVL3,FADS2,IDO1,HADHA,TP53,AIG1,ADH1B,SORD,ENO2,FAHD1,IDH2,HSD17B8,LEP,UGT2A3,PTGES3,COMT,NDUFAB1,UGT1A1,CRABP2,ACSS2,SCD5,SLC38A1,CYP2C18,AASDHPPT,LYPLA1,HEXB,MGST3,AKR1C2,ABHD2,AKR1C1,PTGDS,CYP4V2,GAPDH,HACD1,ETFB,LIPA,ACOX1,SLC16A1,CYP7A1,ELOVL4,PGK1,PPARG,NUDT7,SESN2,ADH1A,GSTA1,FAH,GPAM,PRKAB1,FA2H,MCAT,ADIPOQ,AKR1B1,ABHD5,ADIPOR1,CYP3A5,CYP4F12,MSMO1,SDS,RDH10,PLP1,ECHDC1,MGAT4A,ELOVL1,ALOX5AP,ELOVL6,CYP2C9,CBR4,HPGDS,ALDH1A3,BPGM,ACAT1,MECR,ACOT8,GSTM4,PDHA1,MTHFS,CYP1B1,HEXA,ABHD6,IER3,PLA2G4B,ABHD10,ACAA2,ADIPOR2,DEGS1,AUH,PTGES,CYP4F8,ACSL4,CYP27A1,HACD2,MMUT,UST,ACADSB,CYP2F1,GLYAT,PPARA,SLC1A3,CYP26A1,MORC2,MIF,DLAT,HTR2A,ENO1,VDAC1,MBLAC2,ERRFI1,LDHB,NUDT19,PNPLA8,CD36,SLC25A17,ACOT6,PRKAG1,PC,SLC25A42,PHYH,CRAT,ELOVL7,EPHX1,SLC6A8,ETFA,HADH,PCK2,CYP2D6,OGDHL,HACD3,ABHD12,BRCA1,GSTP1,CPT2,LIAS,GPX1,CPT1B,ACADS,IGF1,UCP2,CRYL1,ASPA,OSBP,HSD17B10,PDHB,HACD4,PCCB,ADTRP,FKRP,PFKFB2,LDHA,SLC5A6,AMACR,PGAM1,GSTM2,PLA2G15,PEX13,AKR1A1,SCPEP1,ACACA,IDH1,LDHAL6B,GAD2,PLA2G5,ILVBL,GAMT,PLAA,CYP1A1,CYP2C8,XBP1,GPX4,EHHADH,TECR |
| 6.290e-03 | -5.07 | water-soluble vitamin metabolic process | biological process | GO:0006767 | 62 | 28 | 18204 | 5365 |
AASDHPPT,SLC23A2,AKR1A1,SLC2A3,THTPA,SLC19A3,SLC25A42,ALPL,FOLR1,SHMT1,SLC2A1,SLC19A2,ATP1A2,MMAA,SLC52A3,AKR1B1,MMADHC,MMACHC,SLC25A32,TKTL1,GSTO1,GCLC,MTHFD2L,SLC5A6,PNPO,RGN,MTHFS,GSTO2 |
| 6.290e-03 | -5.07 | positive regulation of transcription initiation by RNA polymerase II | biological process | GO:0060261 | 62 | 28 | 18204 | 5365 |
CAND1,MED17,TP53,WNT10B,NFKBIA,MED31,TAF7,TAF10,MED4,MED29,TAF11,MED23,MED27,GTF2A1,TAF9,MED9,NFKB1,TAF2,MED10,ZNHIT1,MED30,MDC1,SUB1,HNF1B,MED22,GTF2A2,MED11,MED21 |
| 6.290e-03 | -5.07 | macrophage activation | biological process | GO:0042116 | 62 | 28 | 18204 | 5365 |
TLR3,CX3CL1,MIR181C,NMI,IFNG,TLR1,FOXP1,JAK2,TICAM1,TYROBP,TNF,TMEM106A,IL13,PRKCE,CX3CR1,KCNJ8,TLR2,IL4,SYK,CLU,TLR9,AGER,IFNGR1,TLR4,TMEM229B,IFI35,AIF1,TLR6 |
| 6.308e-03 | -5.07 | Ubiquitin-like_dom | interpro domains | IPR000626 | 57 | 26 | 18521 | 5414 |
SUMO2,NEDD8,UBB,TBCEL,UBL4A,TMUB1,DDI1,SUMO3,ISG15,TMUB2,RAD23B,UBTD1,UBTD2,RBCK1,IKBKB,RPS27A,SUMO1,UBA52,UBL3,FAU,SF3A1,USP14,UBL5,TBCE,UBLCP1,UBFD1 |
| 6.317e-03 | -5.06 | positive regulation of protein serine/threonine kinase activity | biological process | GO:0071902 | 127 | 51 | 18204 | 5365 |
TRAF6,KIT,RGCC,DIRAS2,CAMK1,NTRK3,CCND1,CCL19,DIRAS1,FGF1,IL34,TAB1,PSMD10,EZH2,DVL2,MAP2K1,PIH1D1,PTPN1,AKT1,RALB,SRC,GHR,IL1B,TPD52L1,CD40,FGFR1,PSRC1,MIR26B,PROX1,HRAS,PIK3CG,TLR4,ADRB2,CAB39,MAP3K12,TLR6,TCIM,IFNG,MAP3K11,CCNY,TNF,ADIPOQ,PDCD10,DIPK2A,CCND3,RPS3,DUSP19,GH1,ERP29,FERMT2,TRAF2 |
| 6.334e-03 | -5.06 | MIS12 (MIS12 kinetochore complex component) | protein interactions | 79003 | 88 | 36 | 19454 | 5460 |
KLC2,UBE2M,MRPL49,TBC1D4,SERPINA1,CHAMP1,CBX3,ADNP,SPC24,MDC1,PCGF6,MRPL20,MRPL17,FBXW7,TF,HSPA8,MIS12,SKA1,HSP90AA1,TRAPPC4,DNAJC7,YWHAB,YWHAZ,YWHAH,HP,XPO1,YWHAG,DSN1,NDC80,LRIF1,EGLN3,CBX5,NUF2,RBBP4,YBEY,S100A6 |
| 6.334e-03 | -5.06 | EDF1 (endothelial differentiation related factor 1) | protein interactions | 8721 | 88 | 36 | 19454 | 5460 |
ATG16L1,DUSP14,TOP3B,RAF1,TBK1,CFTR,CDC42,JUN,CHMP4C,RPA2,PPARG,LMNA,PRKCA,HEXIM1,RPL31,RPA3,RPS24,EWSR1,HSPA8,STAU1,HNRNPF,H3C1,G3BP2,WWP2,MOV10,ATF1,BICD2,MAPRE1,LRP6,PSPC1,CREB1,CD274,UBE2I,TUBB,RPS16,VIRMA |
| 6.334e-03 | -5.06 | NOP10 (NOP10 ribonucleoprotein) | protein interactions | 55505 | 88 | 36 | 19454 | 5460 |
UBE2H,KPNA1,SNRNP70,ATG3,DCAF4,RC3H2,PPP1CC,XPO1,BTF3,SUB1,MYC,ESR2,RPL10,DKC1,CDK17,PRKRA,FGFBP1,RSRC1,KRR1,SRSF1,DLST,SYNCRIP,RBM34,WRAP53,CTDSP1,H1-3,RPSA,RAF1,RIGI,COIL,NHP2,KRAS,NPM3,HSD17B10,RPL3,SOD1 |
| 6.348e-03 | -5.06 | GPATCH4 (G-patch domain containing 4 (gene/pseudogene)) | protein interactions | 54865 | 226 | 81 | 19454 | 5460 |
RBM34,CBX3,CRKL,RAF1,RPL15,FCF1,AURKAIP1,MAK16,NOC4L,H3C1,TOP2B,TRIP4,RPL31,RPS24,RPL3,SNRNP70,DDX23,ZCCHC9,RPL10A,NOL12,WWP2,GRSF1,IFI16,DDRGK1,NGDN,LYAR,SURF6,ZBTB2,KLF9,DKC1,MYEF2,SRSF1,PHB1,RPL32,ARL4D,PWP2,HP1BP3,LMNA,RPA2,MFAP1,RPLP0,RPL26L1,STAU1,RPL4,FBXW7,DGCR8,BRIX1,UTP23,COIL,NLE1,RPA3,NUP50,RNF113A,RC3H2,FTSJ3,FYTTD1,H1-1,NSA2,NLRP3,UBE2H,OAZ1,CUL3,RPL7A,MYC,RPF2,CEP70,ZNF668,SAMHD1,SNRNP40,RPL35,RPL7L1,TAX1BP1,APEX1,SRPK2,RPL10,ESR2,DDAH2,ZNF330,RBMX2,FGFBP1,RPL37A |
| 6.348e-03 | -5.06 | PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2) | protein interactions | 5296 | 226 | 81 | 19454 | 5460 |
EDEM1,PIK3R1,UBXN6,MOV10,DPP4,STYK1,YWHAB,DNAJC7,CBL,SHC1,RHOG,SMAD4,RAC2,GJA1,CORO1C,WDR6,RAB35,CAV1,CD28,EGLN3,RHOH,CX3CL1,RPS10,ARF6,RPS7,EEF1A1,CRKL,GHR,RND3,PIK3CA,IGF1R,NTRK2,SEMG2,EFNB1,RINT1,CCR5,DDR1,MRFAP1L1,FLOT1,TGFBR2,KRAS,EPHA4,LAMB2,KIT,AR,DNAJC5,PTPN11,PIK3R3,CUL3,NDUFB10,RAB2A,RPS5,EPHA2,NTRK3,HSP90AA1,TRIM23,YWHAZ,RHOB,LAMTOR1,PTEN,GAB1,ACTB,MANSC1,RHOJ,TUBB,CDC42,PRMT2,RND2,SPTBN1,SYK,ACACA,AVPR1B,MET,FGFR1,LMNA,SQSTM1,HSPA8,RHOU,INPPL1,WASF3,SLC31A1 |
| 6.351e-03 | -5.06 | SMARCE1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1) | protein interactions | 6605 | 264 | 93 | 19454 | 5460 |
PAX6,EWSR1,RINT1,TOP2B,BCL7B,MRFAP1L1,MOB3C,MTA2,SMARCB1,RBPJ,SOX2,JUN,NUP153,E2F4,RAF1,NUP35,CCDC172,PGR,BRD9,SIN3A,TNIK,LHX2,HNRNPD,MED4,BCL7C,XPO1,WWP2,TEX12,HMGA1,BAZ1B,EP300,DDIT3,HSPA8,FOS,SMARCD3,ACTL6A,NUP62,ESR2,RBBP4,ACTB,STAT2,PRMT5,RAN,BRMS1,CUL3,EPS8,HNRNPC,MYC,MDC1,MEPCE,STX11,KPNA2,ZNF787,SNIP1,DISC1,CBX3,SMAD1,H2AX,MDM2,KLF1,CAND1,TFE3,H2AZ1,BRD3,KPNA1,TIAM1,MOV10,SS18,MBD3,HMGB1,OIP5,NUCKS1,BANF1,RPA3,HAUS2,HEXIM1,CDR2,TFIP11,RPA2,ING5,SRC,TRIM54,JAKMIP2,MACROH2A1,ENO1,CCNF,MAPRE1,CCHCR1,MECP2,AR,CEP70,BRAP,RSPH1 |
| 6.356e-03 | -5.06 | positive regulation of ubiquitin-dependent protein catabolic process | biological process | GO:2000060 | 104 | 43 | 18204 | 5365 |
FBXW7,SOCS4,GABARAP,PIAS1,DNAJB2,TRIB1,CSNK1A1,CCDC22,PSEN1,TRAF7,SGTA,CLU,GCLC,HECTD1,COP1,STUB1,SMURF1,SOCS5,AKT1,NOP53,BAG2,SUMO2,RCHY1,CDK5RAP3,CSNK1E,ZER1,FBXO22,GSK3A,FZR1,SUMO1,CDC20,USP5,CAV3,DET1,PSMD10,RNF139,DDRGK1,NFE2L2,PTEN,MDM2,DISC1,TGFB1I1,ZFAND2A |
| 6.364e-03 | -5.06 | protein serine/threonine phosphatase activity | molecular function | GO:0004722 | 97 | 41 | 18094 | 5411 |
CAMK2G,PPM1M,CTDSP1,DUSP10,PTPMT1,CDKN3,DUSP21,CTDSP2,PPP4C,PPM1B,RPAP2,SSH3,PPP3CA,BCKDK,PDP2,PPM1G,DUSP18,DUSP3,DUSP9,DUSP14,TAB1,PPP2R1A,DUSP26,PPP1R3C,MTMR6,PPM1K,FIG4,PTEN,PPP5C,SSU72,DUSP6,PPP1CC,PPP2CB,PPP1CB,PPM1D,DUSP1,DUSP22,CTDSPL2,DUSP19,UBLCP1,PPTC7 |
| 6.367e-03 | -5.06 | negative regulation of cell adhesion | biological process | GO:0007162 | 310 | 112 | 18204 | 5365 |
PDCD1LG2,CTLA4,DLG1,SNAI2,MIR221,SFTPD,IL2,MIR183,TNR,CCL25,MIR222,NDFIP1,CYP1B1,CCL21,ARG2,MIR141,MIR125A,ACTN4,CCL28,PLA2G5,TNFRSF14,IL2RA,PTEN,JAK2,MIR29C,ADTRP,PLG,SEMA5A,CDH13,BCL6,AKT1,CXCL12,HFE,SPOCK1,CORO1C,HMGB1,SPINT2,PTPN22,FAM107A,DUSP1,MIR9-1,ATP5F1B,MIR675,DUSP3,CX3CL1,XCL1,DUSP22,IL10,CD164,MIR192,TWSG1,ADIPOQ,VSIR,CD9,IFNA2,MIR30B,MIR21,EPCAM,MIR146A,LILRB4,MIR503,FZD4,GPNMB,IRF1,TNFAIP8L2,RGCC,MIR31,PIK3R1,RUNX1,IL20RB,SOCS5,NF2,UBASH3B,LPXN,EFNA5,YTHDF2,SWAP70,CBFB,CD80,VEGFA,MIRLET7G,MIR181C,RC3H2,AP1AR,LGALS3,MAD2L2,C1QTNF1,IFNB1,PELI1,PPARA,MIR939,BTN2A2,MIR10A,KLF4,CBLL1,PRNP,FGL2,PTPN11,SRC,FOXP3,CD274,LILRB1,ANGPT1,PRDX2,PLXNC1,CDSN,CD86,IDO1,EPHA4,MMP14,CASK,SDC4 |
| 6.373e-03 | -5.06 | cellular response to virus | biological process | GO:0098586 | 87 | 37 | 18204 | 5365 |
IFNG,CALR,SMAD3,ARF1,TLR3,MIR675,IFNB1,TLR7,CCL5,JAK2,LGALS8,CXCL10,OAS1,TRIM6,IFNA10,IFNAR1,IL21,NFKB1,IL6,BAX,JAK1,NLRP3,IL12A,IFIH1,EXT1,IFNK,IFI6,MIR146A,IFNGR1,IFNA2,MIR21,HSP90AA1,CCL19,MIR130A,IRF3,IFNA13,TOMM70 |
| 6.373e-03 | -5.06 | associative learning | biological process | GO:0008306 | 87 | 37 | 18204 | 5365 |
DRD3,SNAP25,ATP1A2,NOG,NEUROD2,PIAS1,NETO1,OPRK1,KIT,CDK5,TACR1,TNR,SLC6A1,COMT,BTG2,ELAVL4,PPP1R1B,TUBA1A,CHRNB2,OPRL1,DBH,RAG1,ASIC1,EIF4A3,DRD1,UCN,SLC1A1,PPT1,MECP2,SLC6A4,TPBG,ADCY3,FOS,SLC7A11,CLN8,KRAS,PDE1B |
| 6.374e-03 | -5.06 | human chr2q33.1 | chromosome location | human chr2q33.1 | 59 | 22 | 26134 | 5823 |
PLCL1,HYCC2,AOX1,TYW5,SPATS2L,NIF3L1,RFTN2,CLK1,MOB4,SF3B1,MAIP1,BOLL,COQ10B,SUMO1,TMEM237,HSPE1,NOP58,STRADB,PPIL3,HSPD1,TRAK2,GTF3C3 |
| 6.381e-03 | -5.05 | CDR2 (cerebellar degeneration related protein 2) | protein interactions | 1039 | 136 | 52 | 19454 | 5460 |
YWHAG,YWHAH,GAS8,KXD1,GMPPA,STX1A,YWHAB,PSMD7,KRT8,EIF4E2,CEP57L1,CDR2L,TMCC2,PRPF18,FZR1,OAZ2,RPSA,HGS,IFT57,NEK9,UQCC2,STX11,ENKD1,PSMA1,TOMM40,NTAQ1,SMARCE1,TTC23,ZNF250,MYC,CCHCR1,FAS,YWHAZ,TRIM23,CHCHD4,GSK3A,ZMAT2,S100A6,SCNM1,CDC20,MKKS,NDN,DYNLL1,BORCS6,CHIC2,FAM161A,CDR2,RPA2,MNS1,FAM50B,TTR,FBXW7 |
| 6.381e-03 | -5.05 | IMPDH1 (inosine monophosphate dehydrogenase 1) | protein interactions | 3614 | 136 | 52 | 19454 | 5460 |
SDHC,SETD4,EMC2,SLC25A32,POLL,RBCK1,DUSP21,SLC25A14,RAF1,TOP3B,DCAKD,SLC25A44,TRIM6,MTCH2,ZNF704,GTPBP8,AGPAT5,BCS1L,DLX1,GUCD1,RBPJ,RPS11,PRNP,HTRA1,NOP9,LAMP2,TMEM11,TMEM70,HSDL1,NDUFC2,DDX5,ARHGEF39,METTL22,DDIT4L,HOXB8,PIP5K1A,EDF1,SOST,CCNF,SLC25A39,DLST,UBE2I,SFXN2,MGST3,KLHDC8B,MRM2,HMGCS1,GMNN,GMPS,NR2E1,DCAF4,CDC73 |
| 6.383e-03 | -5.05 | SCRIB (scribble planar cell polarity protein) | protein interactions | 23513 | 245 | 87 | 19454 | 5460 |
CDC42,CFTR,RPA2,FGFR1,RNF146,GIT2,PRKCA,RPA3,RBM23,RHOU,ARHGEF6,PPP1CC,DNAJC5,PIP4K2C,UBE2H,CCNF,CTNNA1,GSK3A,TRAF7,IRF2BP1,RHOJ,VIRMA,DYRK1A,IL1R2,NUPR1,IGF1R,TGFBR2,MOV10,KLHL9,HDAC6,LRRC40,NOS1AP,STYK1,HRAS,RAC2,DCUN1D1,STX6,ZNF7,CAV1,CDC5L,PRKAB1,RND2,CNPY3,PPP1CB,TSHR,PAK2,IRF2BPL,HSPA8,EP300,RAB5A,STX7,MYC,CUL3,SFN,RAB11A,PKP4,LAMTOR1,RHOB,YWHAZ,HSP90AA1,NTRK3,LMBR1L,LRRC1,ACTB,ZNF263,LGR4,PRKAG1,RND3,OTULIN,UBE3A,ZNF592,KRAS,FLOT1,CLEC18A,YWHAH,YWHAG,CTNNB1,RHOG,MED4,YWHAB,RAB35,GJA1,FAAP100,RHOH,DIRAS3,EGLN3,CEP19 |
| 6.390e-03 | -5.05 | transforming growth factor beta receptor superfamily signaling pathway | biological process | GO:0141091 | 177 | 68 | 18204 | 5365 |
DDX5,COL1A2,FERMT2,PDCD4,FLCN,SFRP1,MSX1,SOST,SMAD3,TGFB2,FKBP8,DUSP22,TP53,NOTCH2,TWSG1,ACVR1C,TMEM100,WIF1,CHRDL1,SMAD4,SMAD5,TGIF2,NOG,ITGB8,USP15,ACVR1B,HFE,SRC,TGFB3,ID1,EXT1,COL3A1,ITGB5,JUN,RGMA,MSTN,LPXN,CITED1,BMPR2,EID2,ZYX,TAB1,SOSTDC1,PML,EGR1,BMPR1A,CAV2,CFC1,FURIN,SMAD1,SMAD9,BMPR1B,RGMB,FOS,MIR21,CHST11,MIR30A,FMOD,FUT8,TGFBR2,MIR212,PPARG,MSX2,SMAD2,MIR183,ACVR1,NDP,SMURF1 |
| 6.394e-03 | -5.05 | negative regulation of inflammatory response to antigenic stimulus | biological process | GO:0002862 | 33 | 17 | 18204 | 5365 |
GPR17,PSMA1,GPX1,NPY5R,SELENOS,YES1,FCGR2B,SRC,FGR,MIR105-1,PSMB4,FURIN,IL10,IL12B,SYK,IL20RB,NLRP6 |
| 6.394e-03 | -5.05 | extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:0097192 | 33 | 17 | 18204 | 5365 |
FGF10,BAX,BAK1,IL2,GSK3A,BAD,ITGAV,BCL2L1,CTNNA1,BAG3,IL1A,FAS,CX3CL1,BCL2A1,BOK,MCL1,IL1B |
| 6.394e-03 | -5.05 | toll-like receptor 4 signaling pathway | biological process | GO:0034142 | 33 | 17 | 18204 | 5365 |
TRAF6,MYD88,CD14,TIRAP,NMI,TICAM2,IRAK4,NFKBIA,TICAM1,TBK1,OAS1,TMEM126A,LY96,TLR4,PIK3AP1,PRKCE,IRF3 |
| 6.394e-03 | -5.05 | TAF2 (TATA-box binding protein associated factor 2) | protein interactions | 6873 | 176 | 65 | 19454 | 5460 |
ELF1,ISG15,PPP2R1A,SOX2,JUN,CENPM,TAF10,DDX42,EZH2,MRPS11,BAG2,FAM76B,RINT1,RIGI,RPL28,MEPCE,KRAS,SEM1,H3C1,XPO1,PPIL4,ZCCHC10,TAF7,BRD3,TAF9,MRPL18,SKIC8,WDR82,SMAD3,CDK9,PRNP,TOP1,FAM98A,CDK7,PPP1CB,SEC22B,WDR77,MFAP1,NUFIP2,HEXIM1,DYRK2,USE1,TOX4,SPATA25,RFC4,RPA3,RGS2,POLR1H,PSMC1,STAU1,MYC,RIT1,RCL1,UBE2H,SMAD2,ATG3,CTTN,ZNHIT6,ELK3,PSPC1,TACO1,TAF11,ESR2,PPP1R10,PSMD6 |
| 6.403e-03 | -5.05 | PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2) | protein interactions | 5504 | 62 | 27 | 19454 | 5460 |
NSFL1C,PRCP,EWSR1,CDK5,PML,NAE1,NCDN,GTF2H5,POLR2G,ISOC1,PDHA1,GINS4,NEK2,PPP1CB,G6PD,DYRK1A,ZNF622,MSN,GSK3A,PPP1R11,TNFAIP8,KDM2A,BICD2,TUFM,PPP1CC,CSNK2A1,SFN |
| 6.403e-03 | -5.05 | SNX4 (sorting nexin 4) | protein interactions | 8723 | 62 | 27 | 19454 | 5460 |
SUPT5H,DUSP18,CFTR,NUDCD3,MECR,RPA2,RHOBTB1,SCLT1,SH3GLB1,LEPR,RPA3,RAB11A,ANKMY2,PTPN5,BICD2,LAMTOR1,DNAJB6,EEF1AKMT3,LMBR1L,XPO5,AGK,SNX2,PRNP,SNX1,DYNLL1,CACYBP,DYNLT3 |
| 6.403e-03 | -5.05 | CCAT1 (colon cancer associated transcript 1) | protein interactions | 100507056 | 62 | 27 | 19454 | 5460 |
JUP,MED23,HBB,EEF1A1,RPL27A,HNRNPK,RPL23A,PGK1,DHX9,HSPD1,RPL27,IGF2BP1,COL1A2,CHTOP,GAPDH,RPL19,RPL22,CAVIN2,TXN,TOP1,RPL35,ACTB,ALB,RPL8,FAU,FABP5,RPS3 |
| 6.403e-03 | -5.05 | ORF3a (ORF3a protein) | protein interactions | 1489669 | 62 | 27 | 19454 | 5460 |
FGFR1,GOLGA5,STX12,PLP2,SLC4A10,TRAF2,IFNGR1,TFG,GOLGA7,BMPR1A,DDR1,DLG1,GAL3ST1,SAYSD1,TRAF6,NAPA,EPHA2,PYCARD,PFDN5,LGALS3,CAV1,MYRF,STUB1,SCAMP2,B4GALT1,STX10,SNX17 |
| 6.403e-03 | -5.05 | FAM9C (family with sequence similarity 9 member C) | protein interactions | 171484 | 62 | 27 | 19454 | 5460 |
STX6,HSBP1,PPP2R5E,STX5,VAMP3,SESTD1,STX1A,GMNN,EXOC1,TPM3,TEX12,NDC80,RIOX2,STX7,GOSR1,TRIM5,SKA1,TRIM11,STX8,CAPN2,MINDY3,AGGF1,BORCS5,CFTR,BORCS6,SNAP29,SNAPC5 |
| 6.409e-03 | -5.05 | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 47 | 22 | 16828 | 4835 |
STK11,GNAQ,HRAS,PIK3CA,SMARCB1,EZH2,GNA11,RB1,CTNNB1,PTPN11,AKT1,IDH2,SMAD4,KRAS,IDH1,FGFR1,PTEN,KIT,MET,TP53,JAK2,FBXW7 |
| 6.409e-03 | -5.05 | SCYL3 (SCY1 like pseudokinase 3) | protein interactions | 57147 | 91 | 37 | 19454 | 5460 |
VAPB,HDAC11,RAB4A,ARCN1,CYC1,BET1,MTCH2,GABARAPL1,OTULINL,GABARAPL2,STX7,MRPS17,INPPL1,ZYX,PPAN,TMT1A,RAB9A,PPIH,RAB5A,LAMTOR1,CNN3,STYK1,ATG9A,RAB11A,XPO1,ATG7,UTP6,COPE,UQCRH,STX6,CAV1,CEP19,ESR2,GYS1,RAP1B,GJA1,TRAPPC10 |
| 6.409e-03 | -5.05 | DCAF5 (DDB1 and CUL4 associated factor 5) | protein interactions | 8816 | 91 | 37 | 19454 | 5460 |
RNF113A,MRPS11,RNF10,PYM1,HSPD1,SIRT7,CCT8,PFDN1,PDRG1,TACR3,SOX2,TULP3,RPS14,CCT5,PIP5K1A,DYRK2,GPBP1L1,SOST,FGFBP1,SYT2,RBMX2,MAD2L1,SFRP4,DYRK1A,CCT7,FZR1,TCP1,PRNP,TYW3,COPS5,SNAP91,PFDN5,PFDN2,PFDN4,PFDN6,CCT2,DCAF4 |
| 6.409e-03 | -5.05 | PTPRJ (protein tyrosine phosphatase receptor type J) | protein interactions | 5795 | 91 | 37 | 19454 | 5460 |
CASC3,RPS6KA4,LGALS8,RHOB,NOS1AP,RHOG,CTNNB1,RAB11A,VIRMA,SFRP4,RHOH,RHOJ,LGALS3,KLK9,HNRNPL,RAC2,PPP2CB,RPL8,HRAS,MET,MAP2K1,SDCBP,JUP,PPP3R2,CDC42,FBP1,IL2RG,ANP32B,RIGI,CTNND1,STX7,TRMO,KRAS,RINT1,CYP17A1,RHOU,BAP1 |
| 6.409e-03 | -5.05 | AMIGO1 (adhesion molecule with Ig like domain 1) | protein interactions | 57463 | 91 | 37 | 19454 | 5460 |
TMEM60,MYORG,ST8SIA4,CD1B,ADIPOQ,PLPP6,STX8,ITM2B,TMEM50B,PICK1,PGA4,GUCD1,SELENOK,EDDM3B,PGAP2,DDX39A,CNPY3,LMO3,ERLIN2,ANKRD46,CXCL9,VIRMA,NOP9,RPRM,DNM2,ADAM21,XPO5,ODR4,AMIGO1,SLC38A1,KCNB1,TSPO,SLC38A7,GJB2,LRRTM1,SLC41A1,CLDN11 |
| 6.409e-03 | -5.05 | TRAPPC13 (trafficking protein particle complex subunit 13) | protein interactions | 80006 | 91 | 37 | 19454 | 5460 |
RAB5C,ATG9A,RAB2A,SLC30A5,CHRAC1,DNAJC10,TRAPPC2L,CBL,IGF2BP1,HNRNPD,PEA15,ARF1,PTEN,TRAPPC10,TRAPPC3,B4GALT1,CMBL,B4GALT3,RAB1B,HSP90AB1,POLE3,UBB,TRAPPC6B,FUT8,PTAR1,CTBP1,UBE2M,FOS,RAB1A,TRAPPC1,SLC39A9,EP300,IGF1R,SLC39A7,SLC39A3,GOSR1,ARL5B |
| 6.429e-03 | -5.05 | TRIM56 (tripartite motif containing 56) | protein interactions | 81844 | 133 | 51 | 19454 | 5460 |
FXR2,DGCR8,RPL4,FBXW7,SAP18,PPM1G,BIRC2,RNF113A,LSM2,RPLP0,ATG16L1,MIR34B,BORCS6,RPL13A,DYRK1A,PRRC2A,ESR2,VIRMA,FGFBP1,PRKRA,ASCC1,DCAF4,HSP90AA1,UBE2H,CUL3,RPL7A,G3BP1,TTC4,TICAM1,TRIP4,LSM14A,TRIM21,ZC3H7A,RPL3,VPS33A,ILF2,SPC24,TOP3B,RAF1,YTHDF2,MIR200C,FAF2,NUDCD3,SOX2,SNX2,CGAS,FUBP3,MIR25,FKBP4,MOV10,IFI16 |
| 6.436e-03 | -5.05 | regulation of lipopolysaccharide-mediated signaling pathway | biological process | GO:0031664 | 28 | 15 | 18204 | 5365 |
CD36,LILRA2,NFKBIL1,TNFAIP3,LACRT,LY96,TRIM5,TRIB1,DEFB114,MIF,PRDX2,PRKCA,TRAF6,CD14,CX3CL1 |
| 6.436e-03 | -5.05 | positive regulation of sprouting angiogenesis | biological process | GO:1903672 | 28 | 15 | 18204 | 5365 |
MIR30B,VEGFA,MIR1-1,MIR126,KLF4,MIR31,FUT1,JAK1,MIR1224,IL10,FGF1,JMJD8,MIR125A,GHRL,SMAD1 |
| 6.451e-03 | -5.04 | ZC3H7B (zinc finger CCCH-type containing 7B) | protein interactions | 23264 | 48 | 22 | 19454 | 5460 |
UBXN6,MOV10,CUL3,GALE,DCAF4,HSP90AA1,EEF1AKMT3,ATXN1L,VIRMA,OARD1,TOP3B,MAP1LC3B,EDF1,MIR7-1,ZYX,MIR205,ZC3H7A,FXR2,G3BP1,PDE2A,MIR16-2,MIR29A |
| 6.451e-03 | -5.04 | H2AC19 (H2A clustered histone 19) | protein interactions | 723790 | 48 | 22 | 19454 | 5460 |
PRKACB,MCM4,ELK4,RPL26L1,BRD3,RIT1,H2BC11,RC3H2,H2AC4,MAD2L1BP,PDHA1,PRKCB,CFDP1,MRPS9,PPM1G,SSU72,PARP2,SSRP1,VIRMA,HMG20A,CETN2,H3C1 |
| 6.451e-03 | -5.04 | FAM177A1 (family with sequence similarity 177 member A1) | protein interactions | 283635 | 48 | 22 | 19454 | 5460 |
TRAF6,ARMCX3,DCUN1D5,SUGP1,DHX38,SEC62,DNAJC25,FATE1,DUSP22,NAPG,RHOJ,SAR1B,TMX2,OSTM1,LORICRIN,JAGN1,ELOVL4,HSD17B11,GTF2F2,DERL1,AKAP1,ODR4 |
| 6.451e-03 | -5.04 | CDC26 (cell division cycle 26) | protein interactions | 246184 | 48 | 22 | 19454 | 5460 |
ANAPC16,NUCKS1,MRPL11,ANAPC13,SOX2,NEK2,IZUMO1,H2AZ1,ANAPC2,FZR1,TOP1,MAD2L1,CDC20,PNOC,CDC16,HMGA1,ACOT8,ANAPC15,CCDC22,ANAPC4,CDC23,BRD3 |
| 6.451e-03 | -5.04 | C17orf75 (chromosome 17 open reading frame 75) | protein interactions | 64149 | 48 | 22 | 19454 | 5460 |
FAS,DRG1,FIS1,FAM174A,TNFAIP6,ATG9A,WDR11,TOMM40,PRNP,GPNMB,EGLN3,FAM91A1,AIFM1,LHFPL4,TFRC,MGARP,VDAC1,NPTN,HUWE1,CD80,TRIM52,LRRN4CL |
| 6.451e-03 | -5.04 | COTL1 (coactosin like F-actin binding protein 1) | protein interactions | 23406 | 48 | 22 | 19454 | 5460 |
HSPA8,HEBP1,RPA3,BAP1,SH3BGRL,RIGI,TAGLN2,STAU1,ACTB,PPIB,JPT1,CD2BP2,CFL1,PGM2L1,CRIP1,MYC,UBE2M,DCAF11,RPA2,EZH2,RAB4A,BRCA1 |
| 6.451e-03 | -5.04 | CYTH2 (cytohesin 2) | protein interactions | 9266 | 48 | 22 | 19454 | 5460 |
ARL4D,ATP5IF1,CYTH1,PRKCB,ARF1,MYD88,RIGI,APEX1,ARF6,SPPL3,YWHAH,IPCEF1,SFN,ARL4A,ARFGAP1,TAX1BP3,GNAQ,VAC14,PRKCA,TRIM23,PIK3CA,FOSL2 |
| 6.451e-03 | -5.04 | ALG1 (ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase) | protein interactions | 56052 | 48 | 22 | 19454 | 5460 |
MAP1B,TOLLIP,KRAS,HSCB,CFTR,TUBA1A,FURIN,RPA2,LMBR1L,CCNF,MAD2L2,EGLN3,BAG3,FAM20C,CUL3,PTPN5,MOV10,DPP4,ATG9A,RIT1,NRP1,NTRK3 |
| 6.455e-03 | -5.04 | TRAF4 (TNF receptor associated factor 4) | protein interactions | 9618 | 201 | 73 | 19454 | 5460 |
AKT1,CUL3,CEP85,GORASP2,SNRPB,AR,BEX3,ATOSB,PFDN2,CCHCR1,ZNF177,BAHD1,PRMT5,SF3B4,TNFRSF9,HEY2,TRIM27,UBE2I,TAX1BP1,SIAH1,SMURF1,ESR2,APEX1,RPL27A,TANK,SUMO1,ING5,FTH1,FRS3,WWP1,CD40,ACTMAP,MIA2,KDM1A,ARHGEF39,TGFB1I1,WWP2,ISYNA1,CTNNB1,UBE2D1,TRAF6,NOS1AP,CBL,RPL10A,USP15,ZNF688,DNM2,RNF144B,CAV1,HMG20A,UBL4A,TOP3B,TRAF2,WBP11,ZNF581,RPS7,DISC1,ZBTB26,PSMC3,HGS,LTBR,ALKBH4,PLSCR1,BCKDK,PICK1,RPL23A,H3C1,ZBTB16,TGFBR2,TRIM37,TICAM1,RPL17,MAGEC2 |
| 6.472e-03 | -5.04 | SNX5 (sorting nexin 5) | protein interactions | 27131 | 130 | 50 | 19454 | 5460 |
IGF1R,PFDN1,RIGI,KRAS,SEMA4C,TOM1,GTF2E2,RAF1,TP53,HGS,TFRC,VPS33A,XPO5,GJA1,SNX17,HRAS,HCLS1,LRRC61,ARF6,SNX2,SNX1,LAMP3,TBC1D5,STK4,LAMP2,VPS26A,AQP2,SMAD4,APPBP2,RAB5A,BAP1,RPA3,STX7,NPTN,FBXW7,SCLT1,VAPB,RPA2,PRKRA,GNAO1,SNX3,DNAJC5,HMOX2,RAB11A,NRP1,FAM221A,LAMTOR1,BLVRA,ATP1B3,SDF2L1 |
| 6.472e-03 | -5.04 | IL13RA2 (interleukin 13 receptor subunit alpha 2) | protein interactions | 3598 | 130 | 50 | 19454 | 5460 |
DCP2,SEMA4C,RAB3B,RNASEL,IL13,PLPP6,SLC25A5,JAK1,IGF1R,MAN1A2,SLC25A23,PIK3CA,UCKL1,B3GNT2,NETO2,METTL15,ECHDC1,CAND1,ADCK1,VPS26C,GLT8D1,HSD17B11,RB1CC1,ORC5,SLC25A46,DAG1,RFC4,LARP4B,IL4,TIMMDC1,NOTCH2,COMMD3,NEK7,STAT1,B4GALT3,SH3BP4,ALG5,ESR2,ZNHIT6,CDC7,B4GALT1,INTS12,PTPMT1,ENDOD1,ST3GAL2,AKT1,TMED4,RFC5,RBM15B,BRMS1 |
| 6.472e-03 | -5.04 | MOSPD2 (motile sperm domain containing 2) | protein interactions | 158747 | 94 | 38 | 19454 | 5460 |
RMDN3,SPINT2,RAC2,STARD3NL,SEC61B,GNG12,SRPRA,PTPN1,CLRN2,SEC63,CX3CL1,DNAJC1,LAMP3,GNG2,LAMP2,DPP4,SLC25A46,PTPN5,RHOG,FAM187B,DERL1,CXCR4,PALM2AKAP2,TMT1A,PXMP2,FKBP8,CLEC12B,SEC62,CDC42,DNAJC25,OTULINL,ST7,PPP3R2,CCDC47,FASLG,STX12,RPN1,SSR1 |
| 6.472e-03 | -5.04 | CDR2L (cerebellar degeneration related protein 2 like) | protein interactions | 30850 | 94 | 38 | 19454 | 5460 |
CCHCR1,YWHAB,ZNF688,YWHAZ,CHCHD4,YWHAG,PRPF31,YWHAH,ZNF250,KXD1,CUL3,SFN,GGPS1,PPP1R18,SVIP,DYNLL1,ZNF655,KRT8,UBE2I,FAIM,CDR2L,SCNM1,TFIP11,CDR2,ZBTB42,SPRY1,SPMIP6,SNAP29,TOP3B,FAM161A,RPSA,EHHADH,STX11,RASD1,GTF2I,SSNA1,OIP5,RINT1 |
| 6.481e-03 | -5.04 | protein folding chaperone | molecular function | GO:0044183 | 64 | 29 | 18094 | 5411 |
HSPA8,HSPD1,FKBP8,RIC3,PFDN2,DFFA,CCT2,CDC123,HSPA14,HSPB6,HSPE1,HSP90AB1,HYPK,HSPB1,CCT5,TCP1,HSPA5,HSP90AA1,WDR83OS,DNAJB6,PFDN1,CCT7,CCDC47,TAPBP,CLPX,HSP90B1,CCT8,CALR,HSPA13 |
| 6.489e-03 | -5.04 | CLTB (clathrin light chain B) | protein interactions | 1212 | 173 | 64 | 19454 | 5460 |
ACTR2,CAPZA2,VPS33A,STK16,AP2S1,TP53,RAF1,HSPE1,ROCK2,DCP2,TRIM26,LSM4,AP1M1,HNRNPA2B1,PQBP1,SCYL2,NOS1AP,ELP6,PDAP1,FOXP1,EDC3,HDAC6,CSNK2A1,SPTAN1,PRNP,FCHO2,AFTPH,OCRL,CHMP2A,ALYREF,TES,PICALM,CHMP1A,LSM2,AP1AR,UBE2M,SPTBN1,CFTR,SYNRG,CNPY3,PPP1CB,STK38,BAP1,TXNL1,HSPA8,GPHN,BICD2,MYO6,LSM6,MAPRE1,AP2A1,SEC13,MYC,NCAPG2,GMNN,MAP3K21,CHMP5,ESR2,DYRK1A,SMAP2,MIDEAS,CCNF,AP2M1,FAM83B |
| 6.495e-03 | -5.04 | postsynaptic signal transduction | biological process | GO:0098926 | 46 | 22 | 18204 | 5365 |
OPRM1,CDK5R1,CRKL,CHRM5,RNF10,LARGE1,GNAI2,PLCB1,RGS10,GNB1,GNAQ,CHRNB2,GNA11,CHRNA7,LY6H,HRH3,CHRM4,PRKCB,CHRM3,KPNA1,CHRM1,ACHE |
| 6.495e-03 | -5.04 | glial cell migration | biological process | GO:0008347 | 46 | 22 | 18204 | 5365 |
CTNNB1,P2RY12,ADGRG1,HEXB,PAFAH1B1,DISC1,CCL2,TGFB2,BMERB1,EPHA4,NDN,RRAS2,MMP14,CDK5R1,CD9,P2RY1,NR2E1,TSPO,RTN4,CCL3,COL3A1,CDK5 |
| 6.502e-03 | -5.04 | anchoring junction | cellular component | GO:0070161 | 902 | 296 | 19108 | 5553 |
FAM107A,CDSN,FLCN,RPL7,CD81,FZD4,PDIA3,POLDIP2,PARD6A,S100A11,PIK3R2,CRB3,TMEM204,AKT1,B2M,CLDN8,ICAM1,CDH13,ACTR2,STX16,RPL12,CDCA3,RPS16,LPXN,CLDN9,EHD3,EPHA2,RANGRF,ITGAV,SHC1,TES,RPS7,SDC4,CLIC4,CNN3,SLC2A1,RPS29,GIT2,LIN7B,RPS11,TRIM29,PCDH9,UBN1,RPLP1,KLHL24,NIBAN2,RPL19,ITGB5,EPHA4,CHP1,DLG1,RPL27,CLDN4,RAP1A,SIGMAR1,OCEL1,GJC1,ITGA2,F11R,G3BP1,YWHAB,RPL31,ABCC2,DAG1,CAV2,DLG4,FLRT2,PPP1CC,TRIM15,LIN7C,PDLIM3,MMP14,CAV3,MSN,LAMTOR3,CNTNAP1,CAPN2,NCK1,ADD1,CTNNA1,PPP1CB,CDH8,IGSF21,CD9,HACD3,PPP3CA,TIAM1,JAML,ATP1A2,RPL4,SLC31A1,CDC42,KCND2,VEZT,RPS14,CD2,CDH11,RPL10A,HSP90B1,ATP1B1,OXTR,MTDH,MAP2K1,RPS2,RPL18,CAV1,KCNA2,BVES,RHOG,MAPRE2,FBP2,PPP1R12A,PPIB,CORO1C,TMEM47,MYH1,MYH2,FHL3,EFNA5,VEGFA,MPP1,CDC42EP4,KRT8,RPS9,NME2,RAP2B,YWHAZ,TMOD3,GJB2,BMPR2,ATAT1,PMP22,PTK7,AKAP12,NCSTN,B4GALT1,ARHGAP21,CD46,NOS1AP,CCN3,TGFB1I1,DPP4,CLDN12,DLG3,GRIA1,VAMP5,SSX2IP,RIGI,RPL37A,RAC2,CLDN11,RPLP2,CDK4,CSRP1,SPECC1L,HMGA1,IGSF11,RPS17,FCHSD2,KCNJ2,LCP2,RPL13A,ADGRL3,CLDN3,L1CAM,JAK2,RPS5,MAPRE1,SRC,LASP1,GDI2,ACTB,RPL3,DSTYK,LCP1,AQP3,GAB1,CTNND1,ARF6,ARPC2,ITGB8,RPL22,ARHGEF6,ITGA6,CLDN14,AIF1L,RPS10,KIT,RPL6,DNM2,RPL8,YWHAH,GJB1,ARPC3,EPCAM,FLOT1,JAK1,IRF2,NF2,CTNNB1,SNAP23,GJA1,PALS2,CD2AP,ZYX,PPFIBP1,ILK,RAB13,YWHAG,HNRNPK,RPL9,SNTA1,RAP1B,KCNJ11,TM4SF20,FERMT2,HSPA8,GJA10,RND3,CCDC85B,CLDN1,NCKAP1,FLRT3,DES,LIMS2,CTNNA2,CDH7,STXBP6,RALA,ARF1,THY1,RRAS2,CASK,CBL,CCND1,RPS13,CD59,RHOB,CAPN1,NRP1,JUP,ITK,RPGRIP1L,ALCAM,PKP4,CYTH1,HSPB1,RPS15,PIK3CA,RPL23,RPS3,KRAS,ESAM,CALR,PABPC1,KRIT1,CTTN,REXO2,CLDN22,RPL7A,NECTIN2,MDC1,RAP2C,RPLP0,CYTH2,YES1,ACTN4,TADA1,CIB2,AJM1,ARL14EP,CXCR4,RHOU,CD151,SDCBP,MME,PIP5K1A,CSK,DCTN4,SCN1B,SLC8A1,CLDN24,HSPA5,PAK2,PDLIM4,CFL1,FGF13,RPS4X,CLDN6,CD99L2,ILDR1,LAP3,RTN4,PIK3R1,PPIA,SLC6A4 |
| 6.510e-03 | -5.03 | KHDRBS2 (KH RNA binding domain containing, signal transduction associated 2) | protein interactions | 202559 | 127 | 49 | 19454 | 5460 |
ACOX1,RPS3,SULT1A3,PRMT5,SF3B4,DEK,FOXA3,HNRNPC,CAPG,PRPF31,FBXW11,PSMD14,CHTOP,CIRBP,BAHD1,IGF2BP1,COP1,DDX5,HNRNPA0,WDR77,RBFOX2,SDCBP,NCOA5,HNRNPH3,NABP1,EHBP1,SYNCRIP,PRR3,HNRNPL,HSP90AB1,MOV10,HNRNPA1,ATG7,CRBN,ZNF688,HNRNPD,RBM3,HNRNPA2B1,FBXO11,EWSR1,HNRNPK,HNRNPDL,RFC3,SUPT5H,RPAP2,ZNF581,TMEM14B,GRAP2,ILF2 |
| 6.519e-03 | -5.03 | glial cell differentiation | biological process | GO:0010001 | 219 | 82 | 18204 | 5365 |
IL1B,CDK5,AKT1,LAMB2,DAG1,LARGE1,MIOS,SLC25A46,SOX2,CLU,AKT2,SRSF1,TLR4,GPC1,FKRP,DUSP10,GPR37L1,WASF3,CDK6,AGER,IFNGR1,HRAS,TPPP,S100A8,MOBP,HDAC11,PTPN11,DLX1,NAB2,BOK,IFNG,ASPA,RAF1,KCNJ10,TNF,LPAR1,GPM6B,KRAS,CERS6,FA2H,CNP,CNTNAP1,GPR17,EIF2B3,HAPLN2,CSK,ID4,FGF10,CTNNB1,NKX6-2,CDKN2C,RHEB,CNTN1,NDP,SOX9,TLR2,MYD88,NR2E1,EGR2,PSEN1,EIF2B5,B4GALT6,METTL14,SOD1,PICK1,DICER1,EMX1,NTRK2,VPS54,MECP2,MYRF,PTEN,PAX6,TUBA1A,PLP1,EIF2B2,MAP2K1,NCSTN,NAB1,DRD1,PTPRZ1,ILK |
| 6.520e-03 | -5.03 | Metastatic brain tumor | WikiPathways | WP2249 | 28 | 17 | 5310 | 1910 |
CDK6,MIR148B,MIRLET7G,MIRLET7B,MIR148A,TP53,MIRLET7C,MIR101-1,MIR34B,MYC,MIR29A,PIK3R1,MIR101-2,MIRLET7D,MIR34C,CDC42,MIR29C |
| 6.522e-03 | -5.03 | STXBP3 (syntaxin binding protein 3) | protein interactions | 6814 | 97 | 39 | 19454 | 5460 |
XPO1,SNRPB,DNAJC5,KDSR,EMC4,PLPP4,NAPA,RHOG,AGR2,PSMD14,RHOB,NRSN1,SNRPD2,PLPPR1,RAC2,LMBR1L,HRAS,EGLN3,TMEM97,KCTD10,SNRPD3,RHOH,RHOJ,CDC42,UBL4A,PRKCA,RPA2,VAMP2,SLC16A1,RPL3,SLC35F2,PMAIP1,SNAP23,RHOU,RPA3,PTGES3,IL1B,KRAS,STAU1 |
| 6.522e-03 | -5.03 | NUSAP1 (nucleolar and spindle associated protein 1) | protein interactions | 51203 | 97 | 39 | 19454 | 5460 |
SOX2,NUP153,PRDX3,UBL3,RANBP1,RAF1,CSNK1E,TAF2,HEXIM1,DDX42,RPS24,RPL23A,PPP1R12A,MACIR,MEPCE,UGP2,UNC119B,H3C1,B2M,MCM3,DDRGK1,CEP70,MYC,USP15,RCL1,GSTA2,PSMD10,MECP2,HP1BP3,CSNK2B,ZNF330,PHB1,CTTN,RAN,CCNF,KLF9,PPP1R10,TMPO,FZR1 |
| 6.522e-03 | -5.03 | DCP2 (decapping mRNA 2) | protein interactions | 167227 | 97 | 39 | 19454 | 5460 |
RPA2,CAPN2,UBE2M,CRKL,RAF1,FNDC8,CHRM3,AGO1,GFPT1,ELP3,DCP2,ARMCX5,AP1M1,COIL,POLA2,RPA3,FBXO3,SLC25A10,HNRNPA2B1,TRIM21,ABCE1,SQSTM1,PDCD1,F9,GGCX,GTPBP2,NXPH3,YWHAG,QPCTL,EDC3,IDE,EGLN3,CCNF,PRSS8,GGT7,PHKB,SFXN2,PSMB1,XXYLT1 |
| 6.526e-03 | -5.03 | purine nucleotide biosynthetic process | biological process | GO:0006164 | 216 | 81 | 18204 | 5365 |
NDUFB8,PAPSS2,ACAT1,NDUFA2,AK5,ELOVL4,ATP5PO,LIPA,SDHB,NDUFC2,ATP5PF,GUK1,NDUFS6,PRPSAP1,TECR,SDHC,PDHA1,NUDT12,ELOVL1,ACACA,NDUFS3,ATP5F1E,DCK,AK3,ADCY2,NME4,GUCY1B1,NDUFB5,ATP5F1D,ATP5MC1,ELOVL7,HACD1,AK2,DCAKD,ELOVL6,ADCY3,ATP6V1A,NDUFB4,NPPC,ADSS2,NDUFB7,NDUFA5,ATP5MC3,NDUFA12,ATP5MK,COX11,NME2,PDHB,DLAT,ACSS2,NME1,PPAT,ATP5F1A,NDUFB10,NDUFAB1,NDUFS8,MTHFD2L,NDUFA1,ATP5PD,SLC25A1,PRPS1,NUDT2,NPR2,NDUFV2,ATP5F1B,NDUFB6,PPT1,ATP5MG,MMUT,IDO1,ADK,NDUFS2,HACD2,GMPS,UQCC3,ATP5PB,STOML2,ACSL4,DNAJC30,ELOVL3,NMRK1 |
| 6.530e-03 | -5.03 | SMAD2 (SMAD family member 2) | protein interactions | 4087 | 367 | 125 | 19454 | 5460 |
RPS14,SPTBN1,UBA52,EID2,HYAL2,FBP2,WWP1,METTL14,STAMBP,TMOD1,LEMD3,SOD1,ARHGEF6,PML,IRF3,SQSTM1,GTF2I,LITAF,IRF7,MEF2A,AKT1,CDC16,MED22,SUB1,RUNX1,ST13,ARFGAP3,SMAD2,OPTN,CCNF,STUB1,PSPC1,TUBA1B,GSK3A,ING2,BUB3,RHOJ,SMURF1,ROCK1,DYRK1A,SMAD5,TP53,CDK4,EEF1A1,HINT3,TRIM62,SMAD1,SOX9,CDK8,PIK3CA,TAF2,SNIP1,CAMK2G,CDC40,HUWE1,TGFBR2,CSH1,RIGI,USP2,COPS5,ZMYND11,SMAD4,SNRNP70,BECN1,DNAJC7,USP15,SMAD3,ARL4D,DCUN1D1,SPPL3,CDK9,CAV1,RASL12,GTF2IRD1,MAP2K1,SLC25A3,MED31,EP300,YAF2,SRI,LMO2,CREBBP,MYC,PAPOLA,HSD17B3,TBC1D1,BRCA1,SP1,RIT1,ZNHIT6,RAN,ANAPC2,RANBP6,MED17,ESR2,NAA15,MED9,E2F4,JUN,SNAPIN,NUP153,PPP2R1A,EZH2,MTA2,HGS,MEF2C,SLC25A5,ATF3,LDLRAD4,FHL3,TRMO,ACVR1B,AP1M1,RPS27A,FLOT1,ANP32B,WWP2,CISH,CTNNB1,SMAD9,STAMBPL1,MED4,WDR82,RGCC,OS9 |
| 6.543e-03 | -5.03 | AGK (acylglycerol kinase) | protein interactions | 55750 | 124 | 48 | 19454 | 5460 |
NDUFA4,SFXN1,RAB18,PAK6,RAF1,KBTBD4,NEU1,TUBA1A,TULP3,SLC25A24,PHB1,C2CD2,PCSK9,AGK,CYSTM1,EGLN3,SLC25A12,WWP2,XPO1,DDRGK1,PPIC,SLC2A1,ATP2C1,RAB29,RNF113A,RAB5A,EP300,DERL1,UFL1,ATG16L1,TIMM10,CFTR,TIMM29,MED23,CCNF,BAD,PRSS8,SFXN2,VIRMA,CUL3,CNNM4,COX11,ATP1A3,SPOP,FAS,LAMTOR1,LMNB1,UBE2H |
| 6.543e-03 | -5.03 | ATXN10 (ataxin 10) | protein interactions | 25814 | 124 | 48 | 19454 | 5460 |
PEG10,EGLN3,SOSTDC1,XPO5,FBXO32,HSPB1,CDK12,DNAJC7,PTGER4,DDRGK1,FAM174A,IFI16,UBE2A,TGFBR2,KRAS,ABCE1,PPP1R12A,GINS4,RAF1,COMTD1,VIRMA,GNB1,PTPMT1,CTNNA1,CCNF,S1PR4,LMBR1L,SERPINH1,MRPS16,TFDP2,CUL3,CDKN3,GSTK1,MYC,HSCB,HSPA8,RPA3,CD40,BAP1,SCLT1,STOM,WWP1,RPA2,CFTR,DUSP22,GABRA1,CCND1,TPT1 |
| 6.560e-03 | -5.03 | NDFIP1 (Nedd4 family interacting protein 1) | protein interactions | 80762 | 100 | 40 | 19454 | 5460 |
STX11,EMC1,UFL1,TOLLIP,TGFBR2,MAVS,FAM168A,NTRK2,RHOU,RUSF1,CD83,FAM8A1,AVPR1B,CTXN1,TSPAN3,PTGFR,SLC22A8,IZUMO1,WWP1,HCST,MAP1LC3B,IFNGR1,MYCT1,TMEM231,GINM1,UQCRH,SMURF1,UBE2L3,CX3CL1,CCR2,MANSC1,SLC11A2,NRSN1,SLC1A1,PTEN,NTRK3,SLC20A1,IFNAR1,CSK,WWP2 |
| 6.560e-03 | -5.03 | CCDC12 (coiled-coil domain containing 12) | protein interactions | 151903 | 100 | 40 | 19454 | 5460 |
CD2BP2,RALYL,WDR83,SF3A1,ATG16L1,PABPC5,E2F4,SNRPN,SNRPE,EZH2,RPA2,CHMP4C,SF3B1,ZC3H11A,CWF19L1,SRSF7,SNIP1,SNRPA,RPL27,MRPS18C,SNRPG,TSSC4,CDC40,RBM22,SNRPB,MYC,PRPF19,HNRNPC,ZCCHC10,ELAVL2,RC3H2,KIAA1143,CWC15,CDC5L,SNRPB2,HNRNPL,TOP1,SNRPA1,SNRNP40,BUD31 |
| 6.568e-03 | -5.03 | chromaffin granule | cellular component | GO:0042583 | 14 | 9 | 19108 | 5553 |
CLU,SRI,DNAJC5,ANXA7,CHGA,ATP8A1,SYT2,CYB561,DBH |
| 6.569e-03 | -5.03 | ANKLE2 (ankyrin repeat and LEM domain containing 2) | protein interactions | 23141 | 198 | 72 | 19454 | 5460 |
TMPO,EGLN3,STX6,LMAN1,DNAJC1,RHOH,HSD17B11,GJA1,RAC2,RAB35,PTPN1,PPP2CB,EEF1AKMT3,RHOG,ESYT1,LAMP3,FAM241A,LAMP2,UBXN6,SLC25A46,MARCHF5,IMMP2L,FKBP8,KRAS,ASF1A,TRIM37,RAB3B,CYP2C9,OR5L1,TMT1A,CTXN1,RPN1,STIM1,PTRH2,RAB4A,PPP2R1A,DNAJC25,CCDC47,SEC63,VIRMA,RMDN3,SEC61B,LMBR1L,CCNF,KTI12,FIS1,HTRA2,RIT1,SDF2L1,NUDT4,RAB11A,STAC3,STX7,CHRNA7,PXMP2,SYVN1,DERL1,RAB9A,RAB5A,OR1M1,RPA3,LGI1,LEPR,GHITM,SSR1,SEC62,CDC42,RFXANK,TMEM106A,OTULINL,RND2,ST7 |
| 6.571e-03 | -5.03 | MLF2 (myeloid leukemia factor 2) | protein interactions | 8079 | 121 | 47 | 19454 | 5460 |
PDE2A,KRAS,BAG2,DNAJB4,FAF1,SRP72,HDAC11,EZH2,SOX2,ISG15,TUBA1A,SLC25A12,EGLN3,PTP4A3,HYPK,RHOH,AIFM1,HSPB1,POU5F1,DNAJC7,GPRASP2,HSPB8,XPO1,MOV10,IRF7,HSPA8,HSPB2,PRKCB,ZKSCAN1,INPPL1,RND2,CDC42,CCND1,ESR2,APEX1,CCNF,LMBR1L,STUB1,DNAJB6,HSP90AA1,FBXW11,PSMD14,BAG3,AR,CUL3,CIAO1,AKT1 |
| 6.584e-03 | -5.02 | LRPAP1 (LDL receptor related protein associated protein 1) | protein interactions | 4043 | 170 | 63 | 19454 | 5460 |
CSNK1E,TPD52,RAF1,IL1R2,TP53,RPSA,DDX42,TAF2,FAM76B,MRPS11,PDIA6,G3BP1,ROCK2,DNAJC30,MEPCE,RIGI,DPP4,FAM20C,PID1,TMA16,PPIL4,COX4I1,CYB5A,LDLR,CD4,HNRNPL,DNAJB9,LYAR,TOP1,G6PD,TOX4,PAK2,MFAP1,NUFIP2,PPM1G,DNAJC3,TMEM106B,VLDLR,RTN4,AKAP1,NUP50,HSCB,PXMP2,POLA2,HSPA5,CABCOCO1,CUL3,SDF2L1,MECP2,DNAJC10,PIP4K2C,AP2A1,CALU,UBE2H,PSPC1,TACO1,CTTN,SF3B4,AP2M1,SEC61B,CTSB,PPP1R10,MAT2B |
| 6.584e-03 | -5.02 | LMO7 (LIM domain 7) | protein interactions | 4008 | 170 | 63 | 19454 | 5460 |
RPA3,DDX39B,BAP1,RHOU,FOS,PML,STAU1,PIAS1,HSPA5,H1-5,WDR77,PPP1CB,CFTR,RPA2,UBAC2,GTF2H5,TMOD1,CSNK1A1,CCNF,CTNNA1,DAPK3,FBXO22,ACTB,SRPK2,VIRMA,SFN,BTF3,PPP1CC,NONO,YWHAZ,SP1,MAPRE1,H1-1,ZYX,ERLEC1,KRAS,TCP11L2,IFNG,RAF1,TBK1,FBP1,E2F4,MAP1LC3B,JUN,ISG15,ACTN4,VPS33A,CHMP4C,CAPZA2,TES,KCTD3,SUMO2,SPTAN1,MIF,MDM2,CDK9,CDC5L,YWHAH,HDAC6,YWHAG,CTNNB1,CNN3,YWHAB |
| 6.584e-03 | -5.02 | E-cadherin signaling in the nascent adherens junction | Pathway Interaction DB | ecadherin_nascentaj_pathway | 33 | 19 | 2226 | 782 |
CTNND1,CYFIP2,CCND1,NCKAP1,AKT1,AP1M1,CTNNB1,JUP,VAV2,CTNNA1,TIAM1,DLG1,CDC42,PIK3R1,PIK3CA,SRC,ARF6,CTTN,NME1 |
| 6.588e-03 | -5.02 | SIK2 (salt inducible kinase 2) | protein interactions | 23235 | 103 | 41 | 19454 | 5460 |
CDH13,HSPB1,YWHAB,YWHAZ,FBXW11,YWHAH,YWHAG,XPO1,PPP1CC,SLC25A1,SFN,LRRC61,EGLN3,VIRMA,DYNLL1,ACTB,YES1,CORO1C,FOLR1,CTTN,ALPL,MYL6,CSNK1A1,GNAI3,ACTR2,ARPC3,PPP1CB,CRTC2,CDC42,ACTN4,PPP2R1A,GABARAPL2,CD59,PPP2R2C,FBXW7,HDAC5,BAG2,EP300,ARPC2,PPP1R12A,GARRE1 |
| 6.588e-03 | -5.02 | NEK9 (NIMA related kinase 9) | protein interactions | 91754 | 103 | 41 | 19454 | 5460 |
MYC,KXD1,RETSAT,UBXN6,CUL3,INSYN1,XPO1,AR,BAG3,BICD2,MED4,HSP90AA1,UBE2H,CCNF,EEF1AKMT3,RAN,MAP1LC3A,PHF21A,HNRNPL,DYNLL1,EGLN3,MDM2,KBTBD4,H1-5,TP53,GABARAPL1,MAP1LC3B,GABARAPL2,NEK7,RPA2,CDR2,BAP1,NEK9,RPA3,GRIA2,EP300,HUWE1,KDM1A,HSCB,GABARAP,SSRP1 |
| 6.588e-03 | -5.02 | MRGBP (MRG domain binding protein) | protein interactions | 55257 | 103 | 41 | 19454 | 5460 |
MRFAP1L1,MRFAP1,RUVBL2,NUP50,RBBP7,BPGM,HNRNPK,RUVBL1,KPNA2,MDC1,RAF1,ACTL6A,MAX,ING5,TUBA1A,ING1,UBR7,MED23,DMAP1,LMNA,VAV2,H2BC1,HEXIM1,PLAC1,H2AZ1,PHF12,VPS72,GATAD1,MEAF6,DAPK1,ACTB,TUBB,SH3BP4,ESR2,MYC,AP5S1,CMSS1,MORF4L1,H2AZ2,HSPB1,BRD3 |
| 6.593e-03 | -5.02 | TTC19 (tetratricopeptide repeat domain 19) | protein interactions | 54902 | 118 | 46 | 19454 | 5460 |
GUK1,TOR2A,IMMP2L,SFXN1,LPAR2,GPD2,FAM136A,RPL18,HOXD12,CMPK1,JUN,HOXB1,HNRNPL,SLAIN2,SLC25A12,PLGRKT,COX14,AIFM1,COX4I1,NAB2,SMG9,ZNF688,HSCB,NME4,SLC25A51,PHB2,UPF3B,COX17,HADHA,RPA2,PAK5,HPS6,HBE1,HBB,CIMIP1,TIMM29,ELMO1,LDB2,TCAP,FBXO22,PARL,S100A6,MLN,HTRA2,SPRED1,GORASP2 |
| 6.593e-03 | -5.02 | NOL8 (nucleolar protein 8) | protein interactions | 55035 | 118 | 46 | 19454 | 5460 |
AURKAIP1,RPL15,RPL18,CBX3,RPL3,RPS24,RPL31,FGF3,RPL28,KRAS,CTNNBL1,MOV10,KPNA1,RPL23,RPL10A,DDX23,ARL4D,SDHAF2,CDC5L,PRNP,RBFOX2,RRAGA,PARD6A,RPLP0,MTRES1,APOBEC3C,SQSTM1,NUP50,STAU1,RPL4,DNAJC8,MYC,DNAJB6,RIT1,MECP2,MYO6,PRKRA,FGFBP1,VPS72,ZNF330,APEX1,SRPK2,ESR2,SNRNP40,RPL13A,RPL35 |
| 6.606e-03 | -5.02 | ARK2N (arkadia (RNF111) N-terminal like PKA signaling regulator 2N) | protein interactions | 147339 | 106 | 42 | 19454 | 5460 |
MED17,SUMO2,TAX1BP1,CDC5L,SRPK2,JUNB,EGLN3,SRP14,UBE2I,SYT2,CSNK2B,CTSK,PLEKHJ1,RPS5,NRP1,INO80E,CDKN3,TCEANC2,CREB3,KPNA6,XPO1,TMA16,CSNK2A1,FGF12,SLC25A51,MRPS33,ZNF692,PTPN4,TCOF1,JAKMIP1,RPL31,PPM1G,SIX5,CBX3,HEXIM1,ZRANB2,SUMO1,SHMT1,UBA52,ZNF263,H2BW1,DDIT4L |
| 6.606e-03 | -5.02 | SLC30A6 (solute carrier family 30 member 6) | protein interactions | 55676 | 106 | 42 | 19454 | 5460 |
RIC3,LAMTOR1,SLC30A5,GORASP2,LAMP3,CSGALNACT2,RAB5C,GPR17,SLC25A46,CIAO1,RAB11A,RAB2A,LAMP2,ESR2,CAV1,NUP35,STX6,ACTB,RAB1B,GJA1,RNF128,HSD17B11,DOK6,KCNA2,CD79B,RAB4A,OTULINL,BET1,TPRA1,FAM234A,ATG16L1,SAR1B,ARF4,TMED7,STX7,RAB3B,KRAS,RAB9A,SYVN1,TMT1A,SPECC1L,RAB1A |
| 6.607e-03 | -5.02 | WASHC2A (WASH complex subunit 2A) | protein interactions | 387680 | 115 | 45 | 19454 | 5460 |
VPS26B,ROCK2,CAPZA1,SUPT5H,KBTBD4,TOP3B,SOX2,DNAJC2,CAPZA2,RAB4A,DNM2,SPTAN1,STX6,VPS26A,TCEANC2,LAMP2,TBC1D5,XPO1,SSX2IP,PPM1G,RPA3,RAB9A,RAB5A,STAU1,STX7,BET1,BORCS6,PAAF1,FGFR1,CPLX2,VAPB,RPA2,SCLT1,UBE2M,RPLP0,GTF2F1,GSK3A,ACTB,RPGRIP1L,VIRMA,ROCK1,RAB11A,MLF1,LAMTOR1,NTRK3 |
| 6.607e-03 | -5.02 | CDH2 (cadherin 2) | protein interactions | 1000 | 115 | 45 | 19454 | 5460 |
EXOC5,MYC,CREBBP,PKP4,NTRK3,RPS26,RHOB,SEC61B,CTNNA1,VIRMA,MRPL23,RHOJ,CCNA2,SPTBN1,MET,HECTD1,JUP,FGFR1,TMEM256,SKP1,CTNNB1,CDH11,DPP4,PIK3R1,TAX1BP3,RHOG,RAC2,PTPN1,RPL8,RPL32,RPS16,EGR2,HPCAL1,SUPT5H,SAPCD1,MRPL49,NHERF1,RPL3,IGF1R,PC,DDR1,CTNND1,PSEN1,RAB8B,EPHA4 |
| 6.607e-03 | -5.02 | KRT6A (keratin 6A) | protein interactions | 3853 | 115 | 45 | 19454 | 5460 |
MEPCE,TRIM37,EMC8,LGR4,RAF1,FBP1,KBTBD4,NUPR1,RNF8,HGS,SMARCB1,EZH2,TFCP2,EED,EFNA3,FZR1,HDAC6,HNRNPA1,COPS5,DIRAS2,CBL,SHC1,DDX39B,PIAS1,STAU1,UCHL3,KDM1A,CFTR,NCALD,NUP62,WTAP,HEXIM1,TFIP11,LMNA,SGTA,ALB,UBASH3B,AP2M1,RNF208,TRIM54,CCDC85B,CUL2,MYC,UBE2H,TRIM23 |
| 6.615e-03 | -5.02 | EXOSC1 (exosome component 1) | protein interactions | 51013 | 109 | 43 | 19454 | 5460 |
RPL9,EIF4E2,EIF2S2,RPS20,PTEN,RPS16,SPPL3,FZR1,KCTD10,ESR2,DYRK1A,BAZ1B,GRB10,BAG3,DIS3L,DDRGK1,SNRNP70,LSM3,RIT1,UBE2H,MPHOSPH6,RBM7,EXOSC4,FHL3,C1D,KRAS,STAU1,STK38,METTL22,RPS4X,RPL17,RFC2,WDR83,SYK,DDIT4L,PTAR1,RPL27A,ATG16L1,EXOSC8,PAK5,GRM2,EXOSC3,SH3GLB2 |
| 6.615e-03 | -5.02 | TSPYL1 (TSPY like 1) | protein interactions | 7259 | 112 | 44 | 19454 | 5460 |
DVL2,LCA5,RNF113A,NPTN,NAP1L3,COIL,FTL,SDC2,MRPS34,LMBR1L,TRIM44,LURAP1,PSMA6,CSNK2B,PRKRA,RPL10,ESR2,ZNF687,CUL3,SYP,RC3H2,TYROBP,RPL3,MRPS17,RIGI,SOX2,RPL15,MAGEA4,RPL8,EEF1AKMT3,FZR1,RPS16,EGLN3,TSPYL4,KIAA0232,SURF6,STK3,MDFI,ZCCHC10,RPL6,CSNK2A1,H2AC4,RPL10A,BRD3 |
| 6.615e-03 | -5.02 | IMP3 (IMP U3 small nucleolar ribonucleoprotein 3) | protein interactions | 55272 | 112 | 44 | 19454 | 5460 |
RPLP0,TFIP11,LPXN,NPM3,STAU1,PSMG4,RPA3,SERTAD3,PSMG3,RIT1,H1-1,MYC,RPL7A,VAMP5,ESR2,SNRNP40,ZNF655,CCNF,CHMP4C,SOX2,RPSA,E2F4,TP53,RPS13,RPL17,UTP25,RIGI,KRAS,IMP4,EFHC1,ZYX,RPL31,RPS2,MPHOSPH10,CHCHD1,TPM3,CDK9,RPS10,LYAR,EED,PWP2,SRSF1,KRR1,POLR2L |
| 6.615e-03 | -5.02 | eNOS activation and regulation | REACTOME pathways | R-HSA-203765 | 22 | 13 | 10285 | 3229 |
PTS,DDAH1,LYPLA1,CYGB,WASL,NOSIP,AKT1,HSP90AA1,DNM2,DDAH2,SPR,CAV1,GCHFR |
| 6.615e-03 | -5.02 | CTLA4 inhibitory signaling | REACTOME pathways | R-HSA-389513 | 22 | 13 | 10285 | 3229 |
PPP2R5E,YES1,PPP2R1A,AKT3,AKT1,PPP2CB,PTPN11,CD86,AKT2,CD80,PPP2R5A,CTLA4,SRC |
| 6.615e-03 | -5.02 | Metabolism of nitric oxide | REACTOME pathways | R-HSA-202131 | 22 | 13 | 10285 | 3229 |
HSP90AA1,AKT1,NOSIP,GCHFR,CAV1,SPR,DDAH2,DNM2,DDAH1,PTS,WASL,LYPLA1,CYGB |
| 6.627e-03 | -5.02 | VEGFR2 mediated cell proliferation | REACTOME pathways | R-HSA-5218921 | 258 | 100 | 10285 | 3229 |
PSMB7,JAK2,PSMD3,AHCYL1,PSMB1,PSMA3,PSMB5,PSMC4,PSMA4,PSMB10,PSMB11,IL2,PSMC5,FGFR1,PSMA2,PSMB6,CSK,BRAP,DLG4,PPP5C,SPTBN1,PSME1,ANGPT1,FGF17,PSMD7,PSMD14,PRKCA,PPP2R1A,UBB,CSF2,PRKCB,JAK1,FGF7,PSMD12,SHC3,RAP1A,PSME2,FGF3,HBEGF,PSMD6,IL2RA,SPRED2,PSMB9,MAP3K11,DUSP10,NEFL,IL2RG,YWHAB,FGF1,PPP2R5A,DUSP6,PAQR3,MET,PSMA5,FGF23,PPP2R5E,SPTAN1,PEBP1,PSMB3,FRS3,PSMD10,DUSP9,SRC,FGF10,RAP1B,KRAS,MAP2K1,WDR83,FGF22,UBA52,RAF1,FGF16,LAMTOR3,CAMK2G,IL2RB,VWF,CUL3,PSMC1,IL5,KIT,PPP2CB,LAMTOR2,HRAS,PSMD1,PSMB2,PEA15,PSMA6,RASGRP3,SHC1,PSMB4,SEM1,VEGFA,DUSP1,PSMC3,PSMA1,RPS27A,IL3,PSMD4,PHB1,SPRED1 |
| 6.647e-03 | -5.01 | PDS5A (PDS5 cohesin associated factor A) | protein interactions | 23244 | 239 | 85 | 19454 | 5460 |
CSNK2B,ALB,LMBR1L,SCN2B,TUBA1B,ZNF330,APLNR,APEX1,VIRMA,ESR2,MATR3,ACTB,PRPF31,PSMD1,AR,USP13,MYC,GPR17,VAMP5,CUL3,STK11,NRP1,TYROBP,DNAJB6,BRCA1,SF3B1,HSPA8,MAVS,CXCR4,BAP1,RPA3,SIRT7,PML,WFDC5,COIL,MARS1,NPTN,RP2,SLC15A1,TIRAP,HCST,FAM234A,H1-5,TPT1,RPA2,EED,ARL4D,PWP2,HRAS,RBM5,MDM2,WIF1,G6PD,FZR1,RPL35A,SUMO2,XPO1,LAMP3,DDRGK1,MDFI,BCL2L1,DDX23,PICK1,MYO1B,TOP2B,CD83,GTF3C3,RAD21,IMMP2L,KRAS,CD80,H3C1,HNRNPK,THRAP3,EEF1A1,MAP1LC3B,JUN,COMTD1,MOB3C,OTULIN,PLD3,CYB5B,SIGLECL1,CBX3,EZH2 |
| 6.649e-03 | -5.01 | orf1ab (1A polyprotein;1AB polyprotein) | protein interactions | 14254602 | 322 | 111 | 19454 | 5460 |
TUBA1B,RPS3,RCBTB1,RTRAF,RPP25L,SC5D,TMOD3,JUNB,CDC20,SLC25A1,IVNS1ABP,ASCC1,RRP7A,EXOSC1,SMAD2,PRIM2,SYVN1,EIF5B,NME4,AATF,PIP4P1,PSMC4,SAMM50,TMOD1,RCHY1,HACD3,SRP14,PTPN1,PWP2,RNF128,SLC39A10,TOP1,MSMO1,LMAN1,SELENOS,ERCC3,ACOT8,TMEM199,GPRASP2,POR,LSM3,AKAP8L,APH1A,TMEM33,ERLEC1,GALNT2,PAGR1,OLA1,FAM162A,TP53,EXOSC8,TIMM8A,RBM34,SURF4,CYB5R3,PIGK,WNT10B,SARM1,RPL37A,RETREG3,AP2M1,ABHD12,RAB11A,USP13,FTSJ3,GPHN,SF3B1,NSFL1C,STAU1,ATAD1,FXR2,POLA2,TOR1AIP2,PGRMC1,NDUFAF3,TOM1L2,SEC62,ARMCX3,PHB1,LAPTM4A,ATP6V1A,AGK,TRIR,OS9,IFIH1,TMEM208,DIS3L,WDR11,WDR12,ANKRD50,MPHOSPH6,DDX1,MT1X,RNF139,PPAN,ATF3,TRIP4,RPL31,TMEM147,DNAJB4,ZNF609,ZBTB16,CCAR1,TXNRD1,CSNK1E,DCAKD,DIRAS1,PPP2R1A,RPL29,ISG15,STIM1 |
| 6.653e-03 | -5.01 | MTARC1 (mitochondrial amidoxime reducing component 1) | protein interactions | 64757 | 65 | 28 | 19454 | 5460 |
SRPRB,HSCB,AKAP1,DERL1,NMRAL1,EXD2,RUSF1,HSPD1,CHRNB2,RND2,QTRT2,CDC42,EPHB6,NAA11,RHOH,MARCHF4,HNRNPL,SPINT2,RAC2,NDUFB4,OPTN,KCNA2,TMEM30A,RHOG,AR,LRRTM1,SLC25A46,NDUFB10 |
| 6.653e-03 | -5.01 | GRAMD1B (GRAM domain containing 1B) | protein interactions | 57476 | 65 | 28 | 19454 | 5460 |
CTXN1,SSR1,OTULINL,DNAJC25,SEC62,ST7,NDE1,ADD2,DERL1,GRAMD2B,TMT1A,TRAPPC4,GTPBP2,STYK1,ANKRD50,TRAPPC14,TRAPPC2L,CSNK2A1,HOMER1,CLRN2,TMPO,VIRMA,DNAJC1,CD47,HSD17B11,TRAPPC10,SEC61B,EXT1 |
| 6.653e-03 | -5.01 | HPX (hemopexin) | protein interactions | 3263 | 65 | 28 | 19454 | 5460 |
TF,GALNT2,AZGP1,CLU,PEBP1,GALNT12,LCN1,EGFL8,ADAMTS1,FGFR1,STX17,HBB,PDE6D,SERPINA1,CCR1,RAF1,CFTR,SOX2,SERPINA3,CDC42,FBXO22,ALB,UBE2H,AGPAT1,HSP90AA1,MED4,PTDSS1,HP |
| 6.671e-03 | -5.01 | TCF dependent signaling in response to WNT | REACTOME pathways | R-HSA-201681 | 238 | 93 | 10285 | 3229 |
PSMB4,SEM1,WIF1,LRP6,H2AC4,CTNNB1,PSMC3,CAV1,PSMA1,H2AC6,RNF146,RPS27A,PSMD4,H2AB1,DVL2,CUL3,PSMC1,FZD6,CREBBP,PPP2CB,PSMD1,PSMB2,AKT1,PSMA6,LGR4,HECW1,PSMD10,CSNK1E,SOX3,EP300,YWHAZ,TERT,BCL9,UBA52,DKK1,CTNNBIP1,PPP2R5A,PSMA5,PPP2R5E,PSMB3,H2BC14,PSME2,SFRP1,PSMD6,PSMB9,TNKS2,H2AC14,CSNK2A1,H2BC1,H2BC9,SOX9,H2AC7,H2AZ2,H2AZ1,RUVBL1,MYC,SOST,PSMD12,H2AX,TLE1,H2AJ,AKT2,XPO1,CSNK1A1,CDC73,USP8,FZD4,PSME1,PSMD7,H2BC12,PSMD14,KLHL12,CTBP1,PPP2R1A,UBB,PSMB7,CSNK2B,PSMD3,PSMB1,H3C1,SOX2,PSMB5,PSMA3,PSMC4,H2BC17,PSMA4,PSMB10,PSMC5,PSMB11,PSMB6,PSMA2,H2BC11,TNKS |
| 6.674e-03 | -5.01 | Tumor necrosis factor alpha-induced protein 8-like | gene3d domains | 1.20.1440.160 | 4 | 4 | 14470 | 4137 |
TNFAIP8L3,TNFAIP8L1,TNFAIP8,TNFAIP8L2 |
| 6.689e-03 | -5.01 | GLUTAREDOXIN_2 | prosite domains | PS51354 | 10 | 7 | 12186 | 3388 |
GRXCR1,TXNRD1,GLRX,GLRX5,TXNRD3,GSTO1,GLRX2 |
| 6.693e-03 | -5.01 | SPDL1 (spindle apparatus coiled-coil protein 1) | protein interactions | 54908 | 306 | 106 | 19454 | 5460 |
LANCL1,HSP90AB1,SPTAN1,TCP1,SNRPD3,EIF2S1,RPLP1,RPLP2,GSTA1,RPL23,LYZ,SKIC8,HNRNPA1,XPO1,RPL6,RPS4X,CCAR1,RPS27A,KRAS,LAMB2,TRIM21,EWSR1,RBM3,TMT1A,THNSL1,CTTNBP2,RPL31,NEK9,RPS23,SKA3,TUBB4B,RPL29,MAX,CA8,FCHSD2,ERH,POLR2B,DYNLL1,TUBB,RPL35,ACTB,RPS9,SEC61B,PRMT5,NFKBIA,SRXN1,RIT1,HSP90AA1,CRMP1,RPS5,PSMD14,RBBP8,HMGCS1,MYC,GSTT2B,TRA2B,HSPA8,SF3B1,SEC62,RPL27A,MRPS23,MIF,RPS27L,CAND1,PPP1R18,RPS16,SPPL3,CEBPG,RPL12,MRPS9,USP15,RPS2,GAPDH,KXD1,MSH6,IL12A,CSE1L,THRAP3,H3C1,DHX9,RPL3,FNTB,KBTBD4,RPL22,RPS20,ALB,MRPS28,TUBA1B,RPS3,MAPRE1,SEC13,HSPA5,FBXW7,RPL4,SMC4,KDM1A,SYVN1,FADS2,RPA3,RPL27,DDX46,RPA2,EIF3J,SIPA1L1,RPS14,SPTBN1 |
| 6.706e-03 | -5.00 | positive regulation of cell junction assembly | biological process | GO:1901890 | 110 | 45 | 18204 | 5365 |
CAV1,TPBG,NRP1,SLITRK1,ASIC2,VEGFA,LRRC4B,ADNP,EFNA5,CRB3,GHRL,NLGN2,GPRASP3,FLRT3,AMIGO1,FLRT2,CLDN3,CBLN2,LRTM2,CLDN1,CBLN1,LRRN1,CLSTN3,NTRK2,SDC4,LRRTM1,SMAD3,NLGN1,FERMT2,ROCK1,SLITRK2,SFRP1,SLITRK5,LRRTM2,LRRTM3,OXTR,WNT7A,EPHA2,POLDIP2,S100A10,SYNDIG1,FLOT1,THY1,LRRC24,IL1RAP |
| 6.709e-03 | -5.00 | histone deacetylase complex | cellular component | GO:0000118 | 77 | 33 | 19108 | 5553 |
HDAC6,PHF12,RUVBL2,CDK2AP2,PHF21A,ZNHIT1,RUVBL1,SAP30L,SAP18,DMAP1,SIN3A,HDAC5,BRMS1L,SETD5,MTA3,CFDP1,ING2,HR,MBD3,MIDEAS,MORF4L1,RERE,RBBP7,CSNK2A1,HDAC11,CBX5,DNTTIP1,RBBP4,HINT1,HDAC3,BRMS1,MTA2,SAP30 |
| 6.724e-03 | -5.00 | peptide binding | molecular function | GO:0042277 | 258 | 96 | 18094 | 5411 |
AGER,RANBP6,CLSTN3,GPR22,OPRK1,IDE,FZD4,ADNP,HSPA8,TOMM22,B2M,TLR4,PFDN1,MRGPRX2,CST3,TOMM70,ATP1A3,SLC7A8,GNRHR2,FCGR2B,NLRP6,AVPR1B,PRNP,CMA1,PFDN5,PFDN6,NPY1R,ITM2B,ENPEP,NUP153,TLR2,GPR171,ITGA2,NLGN1,TLR6,PFDN4,NPBWR1,KDELR2,TAPBP,CRIP1,SLC7A9,MME,LDLR,KPNA1,TNPO2,SEC61A1,CLU,LILRB1,PICALM,FURIN,ITM2A,KPNA2,SRP54,BRAP,CRHBP,CHRNA7,HFE,PFDN2,EPHA4,GRPR,NPY5R,ACHE,OXTR,OPRL1,PPARG,CMKLR2,TOMM20,HSP90AB1,BACE1,PEX5L,CRYAB,TOMM40L,GPR37,KDELR1,SEC61A2,NFKBIA,ADRB2,GPRASP2,KPNA6,AP2M1,CALR,OPRM1,MCHR1,APBB3,CD209,GRIA2,FZD6,TGFB2,SRP14,RAMP3,GPR37L1,GRIA1,PGRMC1,KCNIP2,MICB,CD36 |
| 6.732e-03 | -5.00 | TULP3 (TUB like protein 3) | protein interactions | 7289 | 335 | 115 | 19454 | 5460 |
RAB35,COPS2,PPFIA3,GJA1,AASDHPPT,AGK,COPS7B,HNRNPL,DBR1,NOB1,LANCL1,MRPS35,RAB5C,DROSHA,PSMD10,DCAF5,DICER1,CDC23,CBL,MAEA,THNSL1,TRIP4,MEF2C,CDK5,GNL1,KRAS,ZBED1,WDR19,AHCYL1,PCGF6,ANP32B,RFC3,MRPS17,DCTPP1,CSNK1E,MAX,NFE2L1,PRKAG1,AAMP,GTPBP1,PHKB,KBTBD6,GGPS1,CUL3,CAV3,MRPS25,RHOB,THOC3,RNF10,EP300,BIRC2,SERPINB6,MRPS7,ARMCX2,RANBP10,RGL1,HRAS,SDHB,STT3A,MRPS9,BRMS1L,ARF6,MRPS23,CAV1,SLAIN2,CDK9,ZNF24,COPS5,LAMP3,GPRASP2,AKAP8L,KPNA1,PPP1R12A,KLF10,MRPS18B,RING1,TTC4,FN3KRP,TMEM33,NEDD8,ABHD10,RIGI,SMN1,MEPCE,EXOC3,SRP72,CTTN,HYCC1,EIF2S2,CSNK2B,PHAX,RHOJ,BCCIP,DHPS,CCNB1,MORF4L1,RAB2A,RALB,PHKA1,ARHGAP21,DCAF16,PIP4K2C,PNPO,PML,PPM1G,TCEA1,SNX33,GTF2I,SEC22B,ACBD6,EIF2B3,TFB1M,HEXIM1,E2F6,PDCL |
| 6.751e-03 | -5.00 | tissue regeneration | biological process | GO:0042246 | 65 | 29 | 18204 | 5365 |
RUNX1,SOX2,PPP3CA,WNT7A,GJA1,TMEM182,LARGE1,DAG1,KLK6,SELENON,VPS54,NINJ1,CD81,FKRP,IFRD1,CD9,PLG,PTN,IGF1,WNT10B,CDKN1A,KPNA1,BCL9,MTPN,CCN3,FGF10,GPX1,EZH2,MSTN |
| 6.751e-03 | -5.00 | positive regulation of synapse assembly | biological process | GO:0051965 | 65 | 29 | 18204 | 5365 |
IL1RAP,LRRC24,CLSTN3,SYNDIG1,NTRK2,CBLN1,LRRN1,LRTM2,FLRT2,CBLN2,AMIGO1,FLRT3,GPRASP3,NLGN2,GHRL,WNT7A,OXTR,ADNP,EFNA5,LRRTM3,LRRC4B,LRRTM2,SLITRK5,SLITRK2,ASIC2,NLGN1,SLITRK1,TPBG,LRRTM1 |
| 6.803e-03 | -4.99 | response to acid chemical | biological process | GO:0001101 | 142 | 56 | 18204 | 5365 |
MIR95,SLC1A2,PCNA,IGF1R,HNRNPD,SESN3,HPCA,COL1A2,TAF9,GLRA1,TNF,PIK3CA,KCNB1,F7,RRAGA,EP300,TOMM70,TMBIM6,AIFM1,SH3BP4,SST,COL3A1,GCLC,LAMTOR3,STAMBPL1,TUBA1A,KRT8,LAMTOR2,VEGFA,MIR545,EIF2S1,RRAGB,MIR455,AQP2,GLRA2,BCL2L1,SLC38A9,ATP2B4,NTRK2,CAPN2,UFL1,AMIGO1,SESN2,MIR342,MIR421,MYD88,CASTOR2,CDKN1B,GRIA1,CUL3,CPEB1,CDO1,NQO1,LAMTOR1,KLHL22,XBP1 |
| 6.809e-03 | -4.99 | ependymoblastoma_Grade_IV | COSMIC cancer mutations | ependymoblastoma_Grade_IV | 4 | 4 | 16828 | 4835 |
TP53,TERT,CTNNB1,PTEN |
| 6.809e-03 | -4.99 | endometrium-hyperplasia-complex | COSMIC cancer mutations | endometrium-hyperplasia-complex | 4 | 4 | 16828 | 4835 |
KRAS,CTNNB1,PIK3CA,PTEN |
| 6.809e-03 | -4.99 | muscle | COSMIC cancer mutations | muscle | 4 | 4 | 16828 | 4835 |
MYD88,KIT,CTNNB1,KRAS |
| 6.809e-03 | -4.99 | central_nervous_system-temporal_lobe-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-oligoastrocytoma_Grade_II | 4 | 4 | 16828 | 4835 |
IDH2,CDKN2C,PTEN,IDH1 |
| 6.809e-03 | -4.99 | central_nervous_system-temporooccipital-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-temporooccipital-primitive_neuroectodermal_tumour-medulloblastoma | 4 | 4 | 16828 | 4835 |
TP53,CTNNB1,IDH2,IDH1 |
| 6.809e-03 | -4.99 | central_nervous_system-temporal_lobe-glioma-rhabdoid_glioblastoma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-rhabdoid_glioblastoma | 4 | 4 | 16828 | 4835 |
TP53,SMARCB1,IDH1,IDH2 |
| 6.809e-03 | -4.99 | complex | COSMIC cancer mutations | complex | 4 | 4 | 16828 | 4835 |
PTEN,PIK3CA,KRAS,CTNNB1 |
| 6.809e-03 | -4.99 | endometrium-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-undifferentiated_carcinoma | 4 | 4 | 16828 | 4835 |
CTNNB1,KRAS,PTEN,PPP2R1A |
| 6.809e-03 | -4.99 | bone-humerus-chondrosarcoma-conventional | COSMIC cancer mutations | bone-humerus-chondrosarcoma-conventional | 4 | 4 | 16828 | 4835 |
IDH2,IDH1,TP53,HRAS |
| 6.809e-03 | -4.99 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | 4 | 4 | 16828 | 4835 |
TP53,CTNNB1,KRAS,KIT |
| 6.809e-03 | -4.99 | haematopoietic_and_lymphoid_tissue-adrenal_gland-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-adrenal_gland-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 4 | 4 | 16828 | 4835 |
KIT,KRAS,CTNNB1,PTEN |
| 6.809e-03 | -4.99 | meninges-meningioma-rhabdoid | COSMIC cancer mutations | meninges-meningioma-rhabdoid | 4 | 4 | 16828 | 4835 |
NF2,IDH1,AKT1,IDH2 |
| 6.809e-03 | -4.99 | central_nervous_system-parietooccipital-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-parietooccipital-primitive_neuroectodermal_tumour-medulloblastoma | 4 | 4 | 16828 | 4835 |
IDH1,IDH2,CTNNB1,TP53 |
| 6.809e-03 | -4.99 | haematopoietic_and_lymphoid_tissue-head_neck-lymphoid_neoplasm-NK-T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-head_neck-lymphoid_neoplasm-NK-T_cell_lymphoma | 4 | 4 | 16828 | 4835 |
KIT,KRAS,CTNNB1,TP53 |
| 6.809e-03 | -4.99 | central_nervous_system-cerebral_cortex-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-cerebral_cortex-glioma-oligodendroglioma_Grade_III | 4 | 4 | 16828 | 4835 |
IDH1,PTEN,IDH2,TP53 |
| 6.809e-03 | -4.99 | rhabdoid_glioblastoma | COSMIC cancer mutations | rhabdoid_glioblastoma | 4 | 4 | 16828 | 4835 |
TP53,IDH2,IDH1,SMARCB1 |
| 6.821e-03 | -4.99 | Nucleic acid-binding proteins | gene3d domains | 2.40.50.140 | 84 | 35 | 14470 | 4137 |
RPA3,MEIOB,EXOSC3,RPA2,CARHSP1,RPS23,DIS3L,SSBP1,EIF1AX,PSMC4,KARS1,RPL8,MRPS17,CCAR1,NABP1,EIF2S1,EIF1AD,RADX,MCM3,LIG3,PSMC5,PSMC1,POLR2G,MCM8,RPS28,POLR3H,STN1,PSMC3,MCM6,MCM4,EIF5A2,ZCCHC17,IFI16,RMI2,EXOSC1 |
| 6.841e-03 | -4.98 | CRK (CRK proto-oncogene, adaptor protein) | protein interactions | 1398 | 361 | 123 | 19454 | 5460 |
H1-3,TUBA1A,GFPT1,FASLG,CRKL,TUBB4B,RTCB,ATF3,SCYL2,PLSCR1,FSTL1,KCTD17,PTPN4,DCP2,LASP1,KIT,YWHAG,XPO1,INO80E,PIK3R1,MAPK4,RPL23,HSPB1,CBL,LYZ,NCK1,KRT8,CORO1C,TSG101,HSP90AB1,CEP19,ELK1,TRIM15,BUD31,HSH2D,SETD9,LNX2,CNDP2,NUFIP2,VAV2,DDX5,HSPA8,RNF41,PSMC1,SRM,EYA3,PAFAH1B2,SERPINB6,BAG3,SFN,PIK3R3,RAB11A,TM4SF19,SERPINH1,RPS5,YWHAZ,ELMO2,PHF21A,AP2M1,ELK3,DOK4,TUBB,ACTB,TCAP,EEF1A1,TP53,KBTBD4,VAC14,PIK3CA,DHX9,IGF1R,SOS2,TCOF1,PPP1R12A,CAPZA1,SOCS2,CSE1L,HUWE1,EDC3,MPG,SHC1,PTPN1,EPHB6,ESD,TWIST2,PRNP,PLG,CD2AP,AGO1,SPR,MYLIP,WDR83,MET,EPYC,FGFR1,PTPN22,LMNA,COX6C,SEPTIN6,RPA3,INPPL1,CORO6,HSPA5,PIK3R2,STK38,KDM1A,NPM3,AR,FAM110B,PTPN11,PTTG1,AP2A1,NCKIPSD,IVNS1ABP,ADGRL3,UBASH3B,GAB1,RPS3,SRC,KCNJ3,ELMO1,NDN,STAT5A |
| 6.851e-03 | -4.98 | regulation of cell differentiation | biological process | GO:0045595 | 1622 | 522 | 18204 | 5365 |
MIR210,CD80,CD36,MAD2L2,SIN3A,PAX6,MIR204,WNT10B,CPNE1,MSX2,ANAPC2,SFN,SYT4,MIR21,MIR30B,IFNA2,INHA,CDC73,MIR519D,TLR9,PLCB1,TNFRSF1B,SMARCD3,EMP2,RTN4,HDAC3,SMURF1,GPRASP3,ZBTB16,RGCC,GLIPR2,CREBL2,TP53INP1,EIF4E,MIR379,HAPLN2,IL6,ID4,BTG1,BGLAP,MMP9,CD86,MIR107,ASPM,CXCL9,FOXP1,YWHAG,NKX3-2,TMEM100,MIR223,MIR185,MMP14,IL12B,MOSMO,HAX1,MTA3,MIR10A,SPRY1,MIR130B,NEUROD2,PPARA,GPR137,SMARCE1,VEGFC,KLHL25,GPR37L1,JUNB,PPP1R12A,ACTL6A,PNP,PLXNC1,LDLR,FOXP3,ERRFI1,CDK5RAP3,L1CAM,GSK3A,RGMA,MIR448,BAD,CD34,JAK2,PTEN,MIR573,NR1H2,STAT1,NRP1,GNB3,PLA2G5,CTDSP1,CDK12,SS18,CCND1,MIR221,MIR130A,IL2,TGFBR2,SOD1,CARTPT,AR,RND2,XBP1,MIR320A,DLK2,EIF2AK2,MIR206,KIT,ANP32B,RBBP4,CTNNB1,NPR2,MAP1B,VDR,MT3,TOX,IGF1,NFKBIA,EP300,BRD9,SPRED1,MIR675,TCF23,CALR,SKIC8,ASPA,PRMT5,GPC1,DRD3,SDHAF2,SMAD4,SLC45A3,EID2B,VSTM2A,PPP3CA,WNT7A,AKT1,IL1B,TGFB3,MTA2,IL23A,BMPR2,TFE3,SEMA7A,VEGFA,NF2,UBASH3B,PRMT6,SOX3,FBXO7,NFE2L2,MIR137,IL15,BMPR1A,MIR181C,PRELID1,FGF23,SLITRK1,SMARCB1,MECP2,TLCD3B,NIBAN2,NTRK2,FZD4,ADIG,LMO3,CCDC3,CTNNBIP1,SHOC2,BLOC1S5,CAMK1,METTL14,NR2E1,PIK3R1,SLC6A6,MIR100,IRF1,AMIGO1,OSM,HOXB8,PDCD4,ROCK1,PAFAH1B1,TIAM1,ZC4H2,TCIM,NLGN1,IFNG,FGL2,MIR140,WIF1,ATF4,THY1,RNF41,LEP,IL18,CCDC85B,DAG1,TMEM176B,UQCC2,OLFM2,IL15RA,NFKB1,TERT,FGF13,GNA11,NPPC,BMPR1B,IL2RA,HCLS1,FOS,DISC1,SOSTDC1,PTHLH,CCL19,RNF10,EEIG1,PIAS1,TRIB1,XRCC5,CTLA4,DMPK,RARRES2,TLR2,G6PD,FXR2,TRAF6,MIR222,WNT2,CCN3,TRIM32,CYB5D2,RAP1A,TRIM62,GPR171,BIRC2,CD2,VSIR,MIR24-1,SMAD3,CERS2,WEE2,ATRAID,PARP2,FBXW7,NME2,TESC,FCGR2B,NOG,HDAC6,STK11,ADIPOR1,MIR205,PITHD1,SYK,PROM1,SAV1,MACROH2A2,ACVR1B,KLF10,HSP90AB1,CBFB,CD28,PTPRZ1,MEF2C,MIR150,EFNA5,MSTN,CAV3,TYROBP,SOCS3,CAV1,TRIM11,IFNB1,MEAF6,RC3H2,CD46,AQP3,MIR149,IGFBP3,CD4,PTN,EGR2,PSEN1,MIR146A,LILRB4,BEND6,MIR208A,LDLRAD4,RUNX1,SOCS5,TCTA,MIR342,SMAD2,IL4,NPTN,MYC,FERMT2,CREB1,SFRP1,FLCN,MIR302B,SOCS2,MIR142,RORB,EFNA3,SOS2,TLR3,EPHA4,DLX1,SMAD5,BTN2A2,CSF2,IL6ST,HEY2,TGIF2,CDK5R1,MTCH2,OPRM1,STK3,FRZB,YWHAH,SASH3,CCL3,CD83,HTR2A,CDK1,LILRB1,FOSL2,LTA,TOB2,MAP2K1,HDAC5,MIR511,CCR1,PPP1CC,TMEM176A,SETD3,TWIST2,MIR200C,IL5,SMAD1,IRF7,MMD,KDM1A,MACROH2A1,ING5,SNAI2,DICER1,IFRD1,BRINP3,MAFG,ADAMTS20,PAEP,MIR20A,CTNNA1,FZD3,TNR,RHEB,SOX9,NDFIP1,FGF10,ADD1,SPRED2,IL2RG,MIR9-1,KRAS,NOTCH2,TGFB2,IL1A,LRP3,MIR144,SEMA5A,ISG15,HAND2,MBD3,PROX1,BHLHE40,GREM1,CEACAM5,SOX2,DKK1,RFLNA,C1QC,SPP1,TMEM182,FAM20C,YTHDF2,B2M,FBXO22,ST7,ATAT1,LHX2,IL7,DROSHA,EZH2,UPF3B,LGALS3,SLC6A4,EPO,S100B,CYP27B1,TGFB1I1,MYRF,IKBKB,IL34,UFL1,PPARG,SFRP4,TSPO,BTG2,CDKN1B,F11R,IMPACT,NREP,PPP2R1A,MIR106A,FAXDC2,PI16,ZNHIT1,SUFU,TNFAIP6,MITF,MIR1-1,CLEC7A,SOD2,MIR34A,DDX5,IL13,SDCBP,BRINP1,ACTL6B,MIR133B,MDM2,STK4,TP53,KLF4,CCL11,TOMM70,PTPN11,MIR590,CDK6,TLR4,LRRC8A,DDIT3,ITGAV,FGFR1,MIR99B,NKAP,PRDX2,CRABP2,TRIP4,HELT,PTPRQ,LAMB2,BRINP2,GHR,AAMDC,ILK,RAG1,ZNF365,MIR424,ADNP,CITED1,RB1,CXCL10,TENT5C,CDK9,F2,CCR2,IRF4,BCL7C,RHOH,ZHX3,PRKCA,GJA1,NEFL,MIR17,MIR214,NLRP3,RBM38,ACVR1,LDB1,TESPA1,NKX6-2,MSX1,CX3CR1,MIR145,PRKX,TRIM6,TWSG1,ACTB,ADIPOQ,TNF,LBH,RBBP7,CX3CL1,RAF1,FERD3L,IL10,ROCK2,RBPJ,TBC1D24,MIR98,S100A10,CXCR4,TRIM46,GABPA,AGER,BATF,DUSP10,MIR495,HMGB1,BCL7B,KCTD11,MME,HMG20A,CXCL12,BCL6,KLK6,CDK5,LBX1,RGS2 |
| 6.851e-03 | -4.98 | COPG1 (COPI coat complex subunit gamma 1) | protein interactions | 22820 | 214 | 77 | 19454 | 5460 |
CLEC12B,PHB2,FBXW7,STAU1,BAP1,PPM1G,SOD1,RPA3,WBP2,SIRT7,TAPBP,SF3B1,EP300,FOXS1,RPA2,ADNP,FGFR1,UBE2M,ARCN1,BET1,SEC62,CDC42,GLRA2,DUSP22,CFTR,COPE,DUSP3,BCCIP,ESR2,VIRMA,LMBR1L,ARF1,OPTN,COPZ2,SEC61B,FAS,SPOP,BRCA1,ILK,MYC,CUL3,DEPDC1B,BTF3,ATG101,HUWE1,ARF4,SACM1L,PTGES3,MYO1B,CHMP4C,PPP4C,RNF126,RAF1,PHF23,TP53,H2AX,DRD1,ARF6,SUMO2,CCAR2,TCP1,EGLN3,CDC5L,CD274,GJA1,TES,KCNJ10,ESYT1,AGR2,POU5F1,DHRS7,EMC4,FAM20C,XPO1,HDAC6,DDRGK1,GOLPH3L |
| 6.862e-03 | -4.98 | SYNE2 (spectrin repeat containing nuclear envelope protein 2) | protein interactions | 23224 | 161 | 60 | 19454 | 5460 |
SUPT5H,TP53,DNAJC25,NRM,RPN1,TFRC,STIM1,HDAC11,RAB4A,PDE6D,CYP2C9,TMT1A,LRP3,RAB3B,FKBP8,LAMP2,SLC25A46,MARCHF5,NDC80,YWHAG,YWHAH,LAMP3,RHOG,RAB35,PTPN1,HSD17B11,GJA1,RAC2,DNAJC1,TMPO,LMAN1,NUP62,SEC62,CDC42,RND2,OTULINL,ST7,VAPB,SSR1,SOD1,PML,SIRT7,PRPF4,HSPA8,RAB9A,DERL1,RAB5A,STX7,PXMP2,HSPA5,RAB11A,RPL7A,BRAP,TBC1D16,YWHAZ,PSMD14,OPTN,SEC61B,ESR2,VIRMA |
| 6.862e-03 | -4.98 | AGTRAP (angiotensin II receptor associated protein) | protein interactions | 57085 | 161 | 60 | 19454 | 5460 |
LAMP5,LMNA,NFYB,ARHGAP1,AGTRAP,ISCU,GABARAPL2,NDUFAF3,HSCB,HMGB1,TMEM47,POLDIP2,CYB5D2,TMEM106B,RAB30,ATP5F1E,PMAIP1,PNPO,LMO2,MBLAC2,MGST3,MMD,MYG1,CCNF,TUBA1B,CYB5R3,RETREG3,CYBC1,UBE2I,TMEM31,PDHA1,SCAND1,SH3GLB1,STARD4,TMEM14B,MIEF1,TOP3B,BPIFA2,MRPL11,TP53,PPIF,SPG21,SLC7A14,CPLX1,RIGI,S100B,TCEA2,GAD2,STAR,SMG9,STX1A,TCEANC2,FATE1,ETFRF1,DNAJC1,FNDC9,SNX1,PRPF18,FHIP1B,COQ8A |
| 6.876e-03 | -4.98 | TMEM239 (transmembrane protein 239) | protein interactions | 100288797 | 68 | 29 | 19454 | 5460 |
S100B,TMX2,FGD2,FBXL19,SPG21,TIMMDC1,PDCD1LG2,FTHL17,CLRN1,OTULIN,TMEM31,SDCBP,SCAND1,RETREG3,COQ8A,SSMEM1,MYG1,TMEM248,USP5,SPPL3,DCUN1D1,SNX2,MPP1,SNX1,NTAQ1,FAM174A,SCN3B,MFSD14B,FXYD6 |
| 6.876e-03 | -4.98 | TNFSF18 (TNF superfamily member 18) | protein interactions | 8995 | 68 | 29 | 19454 | 5460 |
CXCR4,TMEM160,ITM2B,SQSTM1,MAN1A2,CERS2,LPAR1,B4GALT7,CERS6,NLGN1,LPCAT3,TMEM126A,FUT8,SLC19A2,NRM,TMEM59L,GOLGA5,TSPAN3,PTPN1,RETREG3,PEX13,MGAT1,TLCD4,NLGN2,KDSR,LRFN3,CSGALNACT2,TMEM70,TMEM30A |
| 6.876e-03 | -4.98 | PLCH1 (phospholipase C eta 1) | protein interactions | 23007 | 68 | 29 | 19454 | 5460 |
HSP90B1,RPLP0,ETFB,APOBEC3D,SOX2,PSMA1,KRAS,RPL28,FLOT1,NTRK2,LAMTOR1,YWHAZ,FBXW11,RHOB,YWHAB,BRD3,CDC16,RAB2A,SFN,YWHAG,YWHAH,MCM4,DNAJC5,CTNNB1,EGLN3,DIRAS3,RAB35,CTNNA1,GJA1 |
| 6.876e-03 | -4.98 | SUPT7L (SPT7 like, STAGA complex subunit gamma) | protein interactions | 9913 | 68 | 29 | 19454 | 5460 |
DYRK1A,MAD2L2,MED17,ZMYM2,UBE2I,FBLN5,KPNA1,TAF9,TADA1,HFE,TADA3,AR,MYC,TAF5L,ENY2,SERTAD1,SGF29,PTN,DR1,SERTAD2,PLAC1,SF3B5,RHOBTB1,TAF10,CDK8,CTLA4,SUPT3H,WDR37,TP53 |
| 6.876e-03 | -4.98 | GEMIN6 (gem nuclear organelle associated protein 6) | protein interactions | 79833 | 68 | 29 | 19454 | 5460 |
LSM2,SIGLECL1,P2RY12,TOX4,SNRPE,GEMIN7,SNRPN,COMTD1,DDIT4L,LSM4,KRAS,SMN1,SNRPG,CD40,SNRPA,GEMIN8,SNRNP70,MYO6,CHTOP,UBE2H,HAX1,NCKIPSD,CUL3,SNRPB,SNRPD3,ESR2,CDC5L,EGLN3,SNRPD2 |
| 6.876e-03 | -4.98 | CTU2 (cytosolic thiouridylase subunit 2) | protein interactions | 348180 | 68 | 29 | 19454 | 5460 |
CEP41,TENT5C,PRNP,CYP4F8,CCNF,S100A6,APEX2,NFKBIA,ZMAT5,CTU1,FAS,PFDN4,FAM219A,CIAO1,FAM174A,CUL3,KRAS,KCTD17,RAB8B,SCPEP1,DNAL4,EP300,RAP2A,VAPB,HECTD1,RRAGA,ACBD6,HCST,FAXC |
| 6.879e-03 | -4.98 | NA-bd_OB-fold | interpro domains | IPR012340 | 88 | 37 | 18521 | 5414 |
EXOSC3,DIS3L,MCM3,MEIOB,MCM4,PSMC1,MCM8,PSMC5,RMI2,RPL8,RPA2,MRPS17,ZCCHC17,CARHSP1,STN1,PSMC4,LIG3,EIF1AD,KARS1,NABP1,EIF1AX,RPS23,EXOSC1,EIF5A2,SSBP1,IFI16,RPA3,RPS11,RADX,RUVBL1,RPS28,MCM6,POLR2G,POLR3H,EIF2S1,PSMC3,CCAR1 |
| 6.879e-03 | -4.98 | Band 7 domain | gene3d domains | 3.30.479.30 | 12 | 8 | 14470 | 4137 |
STOM,PHB1,ERLIN2,FLOT1,STOML3,ERLIN1,PHB2,STOML2 |
| 6.880e-03 | -4.98 | SHMT2 (serine hydroxymethyltransferase 2) | protein interactions | 6472 | 650 | 211 | 19454 | 5460 |
CTNNB1,SYNJ2BP,DDX1,GIPC3,AGR2,H2BC17,SRSF1,HSP90AB1,COX14,RMND1,HMG20A,CCT7,RNF144B,DHX38,SUPT5H,HGS,RND3,PDHA1,DNAJB4,TRIM21,NAB1,HNRNPAB,LDHB,MYC,FBXW11,S100A11,H1-10,CCDC90B,VDAC2,TACO1,MORC4,PPP5C,SSH3,STAT1,NEK7,SHMT1,ATP6V1C1,USP6NL,RAP2A,YAF2,HDAC5,HERC3,PTRHD1,PEBP1,NGRN,BMPR1A,ABCC5,ADRB2,NDUFS2,EIF1B,TPM3,TMOD2,AKAP8L,SMCHD1,TMEM70,CHCHD1,GATAD1,XXYLT1,COX4I1,CD274,SSBP1,DKC1,FUNDC2,CAND1,METTL15,ATP5PB,PSMC3,GFM2,GORASP2,ATF4,PSMG3,UBE2H,OAT,ATP1A1,ENDOD1,SNX14,CSNK2B,FAM210A,IDE,PRKCE,RPGRIP1L,MRPS21,PPP1R8,ACACA,LUC7L3,HEXIM1,TFB1M,IDH2,RPA2,SPRYD4,RNF113A,GFM1,ARFIP1,BAP1,HSPA5,GRPEL1,ZNF207,ATG7,NDC80,BABAM1,HEBP2,MTRF1,MRPS26,RHOG,HP1BP3,ATP6V1A,GATD3,PHB1,SNX1,GTF2E2,IFNGR1,ACTN4,KHDC4,ACO1,TXNRD1,RAF1,FEN1,NTN4,CHMP4C,EZH2,COX8A,HINT2,HSPD1,IMMP2L,ACADS,GGH,PMPCA,CUL3,CUL2,ACO2,NFYA,MTG2,AUH,ILK,TNFAIP8,HSP90AA1,YWHAZ,ATP1A3,TBC1D16,PARL,CHP1,DYNLL1,TAB1,TIMM29,RFXANK,H1-5,ACTL6A,RNF10,HADHA,EXD2,NT5C3A,CFAP119,PAFAH1B2,MLH3,HSCB,UCHL3,GOLPH3L,HDAC6,GRSF1,DNAJC4,EXOC2,ANKRD49,ARL2BP,AIFM1,SLC25A12,PRNP,IL18,PLEKHF2,AURKAIP1,MRPL11,HINFP,APEH,ILF2,NDUFS3,SFXN1,RIGI,MRPS18C,DUSP21,FASTKD5,HSPE1,DNAJC30,BACH1,HUWE1,TUFM,IFNAR1,FBXO7,CREB3,HERC4,DNAJC19,IVNS1ABP,GTF2A1,CAB39,CTTN,CCNF,VIRMA,NDN,COPE,SF3A1,SAP30BP,MTRES1,UBAP1,METTL14,DCTN4,LMNA,METTL2A,SQSTM1,RPA3,PPM1G,UTP23,CRYZ,POLDIP2 |
| 6.889e-03 | -4.98 | ZBTB18 (zinc finger and BTB domain containing 18) | protein interactions | 10472 | 51 | 23 | 19454 | 5460 |
UBB,CYP4F12,CCT7,ZBTB2,HSPA5,KDM1A,TSN,SNX1,TCP1,HSPA8,ZBTB18,CCT8,ATXN1L,GSTP1,ZBTB42,CBR3,CCT2,CTBP1,AMY2B,MYLIP,PRDX1,PIK3R3,CCT5 |
| 6.889e-03 | -4.98 | NDRG4 (NDRG family member 4) | protein interactions | 65009 | 51 | 23 | 19454 | 5460 |
SYNGR1,SIN3A,APLNR,PRNP,CIDEB,TMEM208,HAX1,REEP6,SMPD2,SYP,HAPSTR1,RABAC1,PICK1,YIF1A,ATP5PF,SFT2D2,GPM6A,PLP2,AGTRAP,TP53,SDR16C5,SYNGR3,CPLX2 |
| 6.889e-03 | -4.98 | C1orf226 (chromosome 1 open reading frame 226) | protein interactions | 400793 | 51 | 23 | 19454 | 5460 |
DYRK1A,VIRMA,FLOT1,ESR2,STX7,STX6,RHOH,RHOJ,NKAP,KRAS,AP2M1,GJA1,SMAP2,RHOU,HRAS,BRD3,NTRK3,RND3,FGFR1,RP9,LAMTOR1,RHOG,ZCCHC10 |
| 6.889e-03 | -4.98 | OPRD1 (opioid receptor delta 1) | protein interactions | 4985 | 51 | 23 | 19454 | 5460 |
ADRB2,TOM1,NAPG,SPCS2,OPRK1,GNAZ,PRKCA,PICALM,TFRC,CTXN3,TP53,KLHL3,TMEM237,GNAI2,SIAH1,PRKCE,SEC61A1,GNAO1,RPRM,DOK4,SIAH2,OPRM1,WWP2 |
| 6.889e-03 | -4.98 | DIAPH2 (diaphanous related formin 2) | protein interactions | 1730 | 51 | 23 | 19454 | 5460 |
RAB11A,PMPCA,RHOB,RHOG,LAMTOR1,OAT,NCKIPSD,DDX1,S100A6,RAC2,ANAPC2,RHOJ,FBXO22,TXNDC12,RABIF,VIRMA,ESD,TOP3B,CDC42,CNPY3,RAB4A,RPA2,RTCB |
| 6.889e-03 | -4.98 | USP43 (ubiquitin specific peptidase 43) | protein interactions | 124739 | 51 | 23 | 19454 | 5460 |
HSPA8,SSR3,ATG4A,FTSJ1,FN3KRP,PSMA2,RBBP7,WDR3,MBD3,MTA3,TXNL4A,TMEM165,TRMT6,HRAS,STX10,CSNK2B,RBBP4,MARCHF5,CTNNB1,YWHAH,YWHAG,YWHAZ,YWHAB |
| 6.889e-03 | -4.98 | CNPY2 (canopy FGF signaling regulator 2) | protein interactions | 10330 | 51 | 23 | 19454 | 5460 |
FAM234A,MYLIP,DPP4,DLG3,MAP1S,E2F4,TFRC,UBE2D1,STN1,HSP90B1,GNB1L,CALU,RIT1,DNAJC3,TMEM106B,SEC61B,TRIM24,RBIS,CTSB,FBXL4,NUP35,HSPA5,RIGI |
| 6.889e-03 | -4.98 | RPS10P5 (ribosomal protein S10 pseudogene 5) | protein interactions | 93144 | 51 | 23 | 19454 | 5460 |
SRPRB,RPL17,RPS27A,MEPCE,RPS4X,SLC25A5,RPS24,RPL23A,RPL18,RPS23,RPS11,UBE2M,HEXIM1,WDR77,RPL15,RPS16,MRPL53,RPS3,RPL37A,RPL24,NQO1,RPS26,RPL6 |
| 6.889e-03 | -4.98 | APLP1 (amyloid beta precursor like protein 1) | protein interactions | 333 | 51 | 23 | 19454 | 5460 |
CDKN2C,SAT1,HSPE1,APBB3,SMN1,CDK4,ING5,DDX39A,EEF1A1,CDKN1A,ANXA7,TMSB4X,RAP1B,EIF2S2,CSNK2B,STX5,PNP,PRNP,GSTM4,TCF21,LRIF1,ZNF24,MPHOSPH6 |
| 6.906e-03 | -4.98 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage | 61 | 27 | 16828 | 4835 |
AKT1,PTPN11,IDH2,NOTCH2,CTNNB1,CDH11,EZH2,EP300,PIK3CA,JAK1,HRAS,EWSR1,SF3B1,RUNX1,GNAQ,CDKN2C,JAK2,FBXW7,KIT,MET,PTEN,IDH1,CREBBP,CBL,KRAS,CALR,SRC |
| 6.906e-03 | -4.98 | acute_leukaemia_of_ambiguous_lineage | COSMIC cancer mutations | acute_leukaemia_of_ambiguous_lineage | 61 | 27 | 16828 | 4835 |
PIK3CA,EP300,EZH2,CDH11,CTNNB1,NOTCH2,IDH2,PTPN11,AKT1,GNAQ,RUNX1,EWSR1,SF3B1,HRAS,JAK1,PTEN,MET,KIT,FBXW7,JAK2,CDKN2C,SRC,CALR,KRAS,CBL,CREBBP,IDH1 |
| 6.909e-03 | -4.97 | SNX8 (sorting nexin 8) | protein interactions | 29886 | 40 | 19 | 19454 | 5460 |
TMEM47,ESR2,NFIL3,TOLLIP,FBXW7,RABAC1,MAVS,DVL2,RXRG,LACC1,ATP6V1D,REEP6,POR,POLR3GL,AKT3,TOP3B,MOV10,RAF1,KARS1 |
| 6.909e-03 | -4.97 | PHLDB1 (pleckstrin homology like domain family B member 1) | protein interactions | 23187 | 40 | 19 | 19454 | 5460 |
BAG3,YWHAH,YWHAG,XPO1,SFN,CIAO1,TOP3B,MYC,ATG16L1,YWHAB,YWHAZ,HRAS,SRPK2,RIGI,EGLN3,FBXO22,HNRNPL,FXR2,KRAS |
| 6.909e-03 | -4.97 | DOCK11 (dedicator of cytokinesis 11) | protein interactions | 139818 | 40 | 19 | 19454 | 5460 |
RHOJ,FBXO22,STAU1,KRAS,DUSP3,VIRMA,UQCRH,CCNF,RAC2,YWHAZ,RHOB,ARHGAP5,YWHAB,MOB3C,GCHFR,SFN,CDC42,YWHAG,YWHAH |
| 6.909e-03 | -4.97 | TRPM4 (transient receptor potential cation channel subfamily M member 4) | protein interactions | 54795 | 40 | 19 | 19454 | 5460 |
RAB2A,TOP3B,RAB5C,LAMP3,OTULINL,SEC62,GLO1,RPN1,IFT57,LGALS8,UPK1A,HRAS,CD79B,SEC61B,HNRNPL,ARF6,KRAS,LGALS3,ESR2 |
| 6.909e-03 | -4.97 | WDR24 (WD repeat domain 24) | protein interactions | 84219 | 40 | 19 | 19454 | 5460 |
HNRNPD,SESN2,CCT2,FBXO7,TOP3B,SEC13,SESN3,CCT7,SRPK2,PAEP,SPPL3,MIOS,RRAGB,AIPL1,APPBP2,CASTOR2,RAB9A,KICS2,FAF1 |
| 6.909e-03 | -4.97 | SSH2 (slingshot protein phosphatase 2) | protein interactions | 85464 | 40 | 19 | 19454 | 5460 |
VIRMA,PRNP,FBXW7,ACTB,SSH3,ZYX,NUPR1,HECTD1,YWHAB,CAPZA2,YWHAZ,BAG3,ACTR1A,YWHAH,PPP1CB,YWHAG,XPO1,CFL1,SFN |
| 6.909e-03 | -4.97 | FLRT1 (fibronectin leucine rich transmembrane protein 1) | protein interactions | 23769 | 40 | 19 | 19454 | 5460 |
PCDH17,FGFR1,GPR35,PIK3CA,FLRT3,PIK3R3,TXNRD2,TCAF2,PKP4,PIK3R1,PIK3R2,YES1,VIRMA,TMEM209,DAD1,CTNNA1,DDR1,ADGRL3,C2CD2 |
| 6.909e-03 | -4.97 | CUEDC2 (CUE domain containing 2) | protein interactions | 79004 | 40 | 19 | 19454 | 5460 |
GTF2A1,EWSR1,RPS20,CREB1,CDC20,MAD2L1,CAV1,RNF26,FZR1,PGR,RPL29,SOCS3,SUGP1,NAB2,GTF2A2,CTLA4,FAS,VPS33A,IKBKB |
| 6.915e-03 | -4.97 | VBP1 (VHL binding protein 1) | protein interactions | 7411 | 189 | 69 | 19454 | 5460 |
TUBB4B,KLHL26,ANP32A,CCT5,ACTR1A,TUBA1A,PCGF3,DYNC1I1,XPNPEP1,PDRG1,PFDN1,ENKD1,CCT8,EWSR1,POC1B,EFHC1,SKIC8,DCAF5,NAB2,DCAF11,PPP3CA,MAP4,KARS1,PRPF19,PFDN5,FGF1,ZNF576,FZR1,DCUN1D1,DYNC1I2,EGLN3,CCT7,PPP2CB,EEF1AKMT3,WDR82,SAMM50,DDIT4L,LMO3,SGF29,RPA3,BAP1,DUSP9,RCCD1,PRPF4,STK26,NUBP2,CCT2,DCAF4,RC3H2,PFDN2,PFDN4,UHMK1,UBE2H,RIT1,PFDN6,LMO2,PIK3R3,ANAPC15,TTC33,MTM1,TUBB,TXNDC12,SNRNP40,VIRMA,CCNF,PNMA1,SMAP2,TUBA1B,PHKB |
| 6.918e-03 | -4.97 | amyloid-beta binding | molecular function | GO:0001540 | 89 | 38 | 18094 | 5411 |
PICALM,PFDN6,PFDN5,ITM2B,ITM2A,BACE1,CLSTN3,AGER,CRYAB,CHRNA7,EPHA4,PFDN2,FZD4,GPRASP2,ADRB2,TLR2,NLGN1,ITGA2,ACHE,APBB3,TLR6,PFDN4,GRIA2,TLR4,FZD6,TGFB2,PFDN1,LDLR,RAMP3,CST3,ATP1A3,GRIA1,FCGR2B,PGRMC1,CD36,CLU,LILRB1,PRNP |
| 6.932e-03 | -4.97 | proton-transporting ATP synthase activity, rotational mechanism | molecular function | GO:0046933 | 16 | 10 | 18094 | 5411 |
ATP5F1E,ATP5PD,ATP5F1A,ATP5F1B,ATP5PO,ATP5MG,ATP5F1D,ATP5PB,ATP6V1A,ATP5PF |
| 6.973e-03 | -4.97 | KCNK5 (potassium two pore domain channel subfamily K member 5) | protein interactions | 8645 | 32 | 16 | 19454 | 5460 |
ADIPOQ,TMEM60,VIRMA,COMT,TMEM14A,ATP5PF,VAMP3,SLC66A2,YWHAZ,SMCO4,CYB5B,AGTRAP,GJB2,TOP3B,TMEM176A,ORMDL3 |
| 6.973e-03 | -4.97 | EML1 (EMAP like 1) | protein interactions | 2009 | 32 | 16 | 19454 | 5460 |
TUBA1B,NEK9,KXD1,RPA3,PTEN,MTDH,UBE3A,TUBA1A,AGR2,TUBB,DCUN1D1,ISG20L2,VIRMA,XPOT,SMURF1,GRID1 |
| 6.973e-03 | -4.97 | RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2) | protein interactions | 57186 | 32 | 16 | 19454 | 5460 |
RHOB,RHOG,LAMP3,RAB11A,DLG3,TOP3B,LAMP2,CSK,ESR2,VIRMA,NKIRAS2,DDI1,RHOJ,GFOD1,KRAS,HRAS |
| 6.973e-03 | -4.97 | NAA16 (N-alpha-acetyltransferase 16, NatA auxiliary subunit) | protein interactions | 79612 | 32 | 16 | 19454 | 5460 |
SMURF1,NAA11,PSMD12,HYPK,TCEA1,MRPS11,ALYREF,RPA3,NRP1,FGFR1,SLPI,DDX39A,RIOX2,NAA15,PSMD3,NAA50 |
| 6.973e-03 | -4.97 | CCN2 (cellular communication network factor 2) | protein interactions | 1490 | 32 | 16 | 19454 | 5460 |
MTDH,EP300,VEGFA,KLHL23,FZR1,ACADS,ACTB,SOX2,MYC,CREBBP,RSPH1,CCN3,INSIG2,TGFB3,TGFB2,TRIM68 |
| 6.973e-03 | -4.97 | IL1R1 (interleukin 1 receptor type 1) | protein interactions | 3554 | 32 | 16 | 19454 | 5460 |
MYD88,BMPR1A,IL1A,IL1RAP,MATR3,IL1B,PELI1,TOM1,TOLLIP,YES1,TICAM2,IRAK4,SRC,VPS39,PIK3R1,TRAF6 |
| 6.973e-03 | -4.97 | MSRA (methionine sulfoxide reductase A) | protein interactions | 4482 | 32 | 16 | 19454 | 5460 |
CCNI,UBASH3B,SDHB,IRF3,PPIA,MT2A,WDR44,HNRNPL,TRIM26,HSPE1,KCNMB2,COPS5,RAF1,LYPLA1,UBE2H,FBXL3 |
| 6.973e-03 | -4.97 | AAMDC (adipogenesis associated Mth938 domain containing) | protein interactions | 28971 | 32 | 16 | 19454 | 5460 |
HEXIM1,UBE2H,PIH1D1,RPA2,BAG3,GORASP2,SPC24,NDC80,CDK9,PPP1R10,NUF2,TRIM54,OCRL,HSPA8,LSM12,WDR82 |
| 6.973e-03 | -4.97 | IL24 (interleukin 24) | protein interactions | 11009 | 32 | 16 | 19454 | 5460 |
AKT1,NOTCH2,SMAD4,PIK3CA,BECN1,RB1CC1,S100A6,CCR5,HRAS,EIF2AK2,UBE3A,PTEN,KRAS,FBXW7,ESR2,CLU |
| 6.983e-03 | -4.96 | thyroid-chronic_thyroiditis | COSMIC cancer mutations | thyroid-chronic_thyroiditis | 50 | 23 | 16828 | 4835 |
HRAS,STK11,GNAQ,PTPN11,AKT1,IDH2,RB1,GNA11,CTNNB1,SMARCB1,EZH2,PIK3CA,IDH1,KRAS,SMAD4,JAK2,FBXW7,MET,KIT,TP53,PTEN,FGFR1,TERT |
| 6.983e-03 | -4.96 | chronic_thyroiditis | COSMIC cancer mutations | chronic_thyroiditis | 50 | 23 | 16828 | 4835 |
IDH1,HRAS,KRAS,SMAD4,STK11,GNAQ,JAK2,PTPN11,AKT1,FBXW7,IDH2,GNA11,MET,RB1,KIT,CTNNB1,TP53,PTEN,SMARCB1,EZH2,FGFR1,TERT,PIK3CA |
| 6.989e-03 | -4.96 | ATPase complex | cellular component | GO:1904949 | 147 | 57 | 19108 | 5553 |
RBBP7,RBBP4,ATP5PD,SS18,MTA2,BCL7B,VPS4A,MTA3,CFDP1,ATP5F1A,DEK,SMARCA5,RNASEK,ACTL6B,TFPT,SF3B1,DMAP1,ATP6V0B,ATP5MK,VPS4B,ATP6V1G2,ACTL6A,PPIF,INO80C,ATP5MC1,BRD9,ATP6AP2,ATP6V1D,CHRAC1,SMARCD3,ATP5F1B,ATP5PB,SMARCE1,TMEM199,ATP6V1C1,ATP5MC3,ATP5MG,POLE3,MBD3,SMARCB1,ATP6V0E1,ACTB,ZNHIT1,RUVBL1,ATP5PO,INO80E,RB1,ATP6V1A,ATP5F1D,ATP5F1E,ATP6V1G1,RUVBL2,CDK2AP2,BCL7C,BAZ1B,ATP5PF,ATP6V1E2 |
| 6.998e-03 | -4.96 | amino acid:sodium symporter activity | molecular function | GO:0005283 | 23 | 13 | 18094 | 5411 |
SLC6A11,SLC38A2,SLC38A3,SLC38A1,SLC38A7,SLC6A12,SLC6A1,SLC6A8,SLC1A1,SLC1A2,SLC6A7,SLC1A3,SLC6A6 |
| 7.032e-03 | -4.96 | PPAN (peter pan homolog) | protein interactions | 56342 | 186 | 68 | 19454 | 5460 |
DPP4,IFI16,MOV10,WWP2,MRPS35,ATG7,CSNK2A1,MAP3K14,DDRGK1,SNRNP70,DICER1,DRG1,KRR1,HP1BP3,RB1,ISG20L2,CAND1,RPS16,DKC1,MDM2,MRPS23,STRBP,SOX2,AURKAIP1,TAF1D,RPL15,SMNDC1,HDAC11,HBP1,SNIP1,RPL3,PAK1IP1,KRAS,RPS13,UTP25,MYC,SMARCA5,ZSCAN25,PSKH1,FYTTD1,FTSJ3,UBE2H,RIT1,CCNF,ZNF22,EIF2AK2,CSNK2B,RPL37A,MRPL13,ZCCHC7,SRPK2,RSL24D1,WDR77,SYK,ATG16L1,RPA2,TIMM23,RPL26L1,ZNF574,ZNF770,RPA3,PPM1G,NGRN,SF3B1,EP300,STAU1,MRPS7,BRIX1 |
| 7.062e-03 | -4.95 | regulation of leukocyte adhesion to vascular endothelial cell | biological process | GO:1904994 | 41 | 20 | 18204 | 5365 |
MIR21,MIR146A,KLF4,ST3GAL4,FUT9,MIR141,MIR221,IL6,CCR2,MIRLET7G,CXCL12,MIR125A,CCL25,TRAF6,MIR222,MIR31,CCL28,CHST2,CCL21,TNF |
| 7.062e-03 | -4.95 | negative regulation of cytokine production involved in inflammatory response | biological process | GO:1900016 | 41 | 20 | 18204 | 5365 |
MIR125A,MIR136,MIR222,CHID1,MACIR,IL1R2,PYCARD,PPARA,MIR378A,MIR140,LILRB4,EZH2,MIR146A,MIR98,MIR338,PDCD4,F2,MIR16-1,MIR129-1,MIR221 |
| 7.062e-03 | -4.95 | acetylcholine receptor signaling pathway | biological process | GO:0095500 | 41 | 20 | 18204 | 5365 |
CHRM5,LY6H,HRH3,CHRM3,PRKCB,CHRM4,CDK5R1,GNAQ,OPRM1,CHRNA7,CRKL,GNA11,CHRNB2,PLCB1,ACHE,CHRM1,RGS10,GNB1,LARGE1,GNAI2 |
| 7.068e-03 | -4.95 | kinase inhibitor activity | molecular function | GO:0019210 | 78 | 34 | 18094 | 5411 |
CDKN1A,LRP6,SH3BP5L,MACROH2A1,PKIB,TESC,NCK1,SFN,CDKN2D,DNAJC3,DUSP19,RHOH,TRIB1,SOCS3,HYAL2,CAMK2N2,HSPB1,CDKN2C,AKT1,YWHAG,CAMK2N1,YWHAB,SPRED1,HEXIM2,CDKN1B,SPRED2,GSKIP,PPP1R1B,CAV1,CHP1,LILRB4,HEXIM1,PKIA,PKIG |
| 7.074e-03 | -4.95 | ZSCAN25 (zinc finger and SCAN domain containing 25) | protein interactions | 221785 | 71 | 30 | 19454 | 5460 |
CSNK2A1,E4F1,RPL7A,RPS2,H1-1,PRR3,RPS9,RPS3,KRR1,SURF6,RPL19,VIRMA,RPS10,H2AX,H1-3,ZSCAN1,FGF13,IPO8,NOTCH2,WTAP,SART3,LLPH,RBM34,SCAND1,RPL23A,RPL3,RPL31,PPAN,SRSF4,UTP23 |
| 7.074e-03 | -4.95 | COMMD3 (COMM domain containing 3) | protein interactions | 23412 | 71 | 30 | 19454 | 5460 |
TNFSF8,G3BP1,RPS15,MIA2,COMMD2,CNKSR3,BANF1,BAP1,SH3GLB1,SCLT1,STMN2,JUN,COMMD8,NUP62,GNB1,COMMD6,VPS26C,ZNF740,DDX1,CCDC22,COMMD9,FAS,ATG7,INSYN1,COMMD5,CFL2,LAMP3,MYC,MOV10,NFKB1 |
| 7.074e-03 | -4.95 | DOK4 (docking protein 4) | protein interactions | 55715 | 71 | 30 | 19454 | 5460 |
UBLCP1,SUPT4H1,ELK4,SUPT5H,TOP3B,PICALM,CCM2,CTBP1,QRSL1,IGF1R,UBE3A,OPRK1,ANAPC16,RHOU,BCL7B,AHCYL1,KDM1A,BTF3L4,BAG3,OPRM1,PFDN5,CMSS1,STK24,PHKB,LIX1,HMG20A,SRC,KBTBD6,ELK1,STAT2 |
| 7.082e-03 | -4.95 | benign_melanocytic_nevus | COSMIC cancer mutations | benign_melanocytic_nevus | 34 | 17 | 16828 | 4835 |
TP53,CTNNB1,KIT,GNA11,LMNA,PPFIBP1,AKT1,PIK3CA,TERT,TPM3,KRAS,HRAS,LSM14A,GNAQ,STK11,BAP1,GOLGA5 |
| 7.091e-03 | -4.95 | Vbp1 (von Hippel-Lindau binding protein 1) | protein interactions | 22327 | 10 | 7 | 19454 | 5460 |
BAP1,PFDN5,PFDN4,PDRG1,PFDN2,PFDN1,PFDN6 |
| 7.091e-03 | -4.95 | KCNJ5-AS1 (KCNJ5 antisense RNA 1) | protein interactions | 219833 | 10 | 7 | 19454 | 5460 |
PLEKHF2,FRS3,GPSM3,EFHC1,HAPSTR1,DDX39A,FBXO44 |
| 7.091e-03 | -4.95 | RPL13P12 (ribosomal protein L13 pseudogene 12) | protein interactions | 388344 | 10 | 7 | 19454 | 5460 |
RPA3,CUL2,CUL3,COPS5,RPA2,CAND1,RAD21 |
| 7.091e-03 | -4.95 | GGACT (gamma-glutamylamine cyclotransferase) | protein interactions | 87769 | 10 | 7 | 19454 | 5460 |
PLAAT5,COPS7B,ZBED1,LDB2,ORMDL1,RPL23A,CUTA |
| 7.091e-03 | -4.95 | ADAT1 (adenosine deaminase tRNA specific 1) | protein interactions | 23536 | 10 | 7 | 19454 | 5460 |
VIRMA,APEX1,SNRNP40,QTRT2,CFTR,MOV10,TOP3B |
| 7.091e-03 | -4.95 | RPSAP12 (ribosomal protein SA pseudogene 12) | protein interactions | 387867 | 10 | 7 | 19454 | 5460 |
DCUN1D1,NEDD8,CAND1,CUL2,CUL3,EWSR1,COPS5 |
| 7.091e-03 | -4.95 | ARMH4 (armadillo like helical domain containing 4) | protein interactions | 145407 | 10 | 7 | 19454 | 5460 |
BMPR1A,TP53,VIRMA,BMPR2,NDFIP1,FGFR1,ELAPOR2 |
| 7.097e-03 | -4.95 | TLC | prosite domains | PS50922 | 17 | 10 | 12186 | 3388 |
TRAM1L1,TRAM2,TLCD3B,TLCD1,CLN8,TLCD4,CERS2,CERS6,TRAM1,TLCD2 |
| 7.097e-03 | -4.95 | TNF_2 | prosite domains | PS50049 | 17 | 10 | 12186 | 3388 |
TNFSF10,TNFSF12,TNFSF13,TNFSF8,TNFSF15,FASLG,CD40LG,TNF,LTA,LTB |
| 7.105e-03 | -4.95 | regulation of membrane potential | biological process | GO:0042391 | 463 | 161 | 18204 | 5365 |
GRID1,BAD,IGSF11,SUMO1,SLC4A8,SRI,GNA11,FGF13,ASIC2,KCNJ8,GSK3A,KCNIP2,GNA14,DRD1,CACNB4,GLRA2,EHD3,KCNH8,SLMAP,CHRM1,KCNA3,BCL2L1,KCNK13,KCNS1,PTEN,SOD1,SLC8A1,ATP1A2,GLRX,CNR1,DLG1,PPIF,SLC29A1,CBLN1,ATP1B1,ATP5IF1,SLC25A27,NLGN2,MLLT11,KCNJ3,PID1,NDP,GLRB,INSYN2B,GJA1,DMPK,CFTR,KCNK17,SCN2B,PLN,GRIA1,GHRL,CNTNAP1,TUSC2,ASIC1,EIF4A3,ATP1A1,TMEM108,BAK1,GABRG2,NPR2,SCN3B,KCNJ10,CACNB3,MUL1,BOK,ALB,UCP2,TNF,RIMS4,ADRB2,TBC1D24,AKT1,KCND2,CDK5,KCNMA1,STX1A,GABRB3,GCLC,KCNG3,PPP3CA,WNT7A,MIR30D,RANGRF,MEF2C,BNIP3L,GPR35,INSYN1,CAV3,CHRNB2,POPDC3,CHRNA7,KCNH1,FKBP1B,PMAIP1,PYCR1,CD36,PRELID1,MECP2,GABRA2,CAV1,SLC6A4,INSYN2A,MIR30B,GJC1,ARL6IP5,PSEN1,LIPA,GRIA2,ATP1A3,NTRK2,KCNK10,KCND3,JUP,TACR1,KCNMB2,MFN1,MIR208A,TSPO,NOS1AP,GABRB2,ZMPSTE24,GNAQ,SOD2,GABRA1,UBB,PRDX3,SCN1B,BAX,POPDC2,ATP1B3,MIR1-1,RIMS3,GLRA1,RGS7BP,WWP2,NLGN1,HCRT,CACNB2,KCNF1,KCNC1,KCNB1,DLG4,FGF12,IFI6,BVES,SNTA1,NETO1,GRM1,ADRB1,SRC,ADRA1A,ADORA1,GRIK1,KCNA2,RNF122,KCNJ11,YWHAH,GABBR1,KCNJ2,MTMR2 |
| 7.113e-03 | -4.95 | ovary-low_malignant_potential_(borderline)_tumour | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour | 12 | 8 | 16828 | 4835 |
SF3B1,PTEN,PIK3CA,JAK2,JAK1,PPP2R1A,KRAS,SRSF2 |
| 7.119e-03 | -4.95 | translation regulator activity, nucleic acid binding | molecular function | GO:0090079 | 106 | 44 | 18094 | 5411 |
EEF1G,EIF1B,EIF4A2,EIF3J,EIF3K,EIF4B,MTRF1,CPEB1,ABCF1,GFM2,TUFM,EIF2S2,RPS27L,EIF3D,EIF1AD,ETF1,PABPC1,GTPBP2,EIF4H,PAIP2B,PAIP2,SHMT1,EIF3E,EIF4E2,EIF2B5,BOLL,EIF2S1,EIF5A2,EEF1B2,TYMS,EIF2B2,EIF1AX,COPS5,EIF3G,GTPBP1,EIF5B,EEF2,EIF4E,EEF1A1,EIF2B3,EIF2D,PAIP1,GFM1,EIF4E3 |
| 7.123e-03 | -4.94 | SMAD_FHA_dom_sf | interpro domains | IPR008984 | 52 | 24 | 18521 | 5414 |
IRF4,IRF3,RNF8,SLMAP,PPP1R8,PHF12,NBN,IRF8,IRF9,SMAD5,APTX,SMAD4,TCF19,SMAD9,SMAD2,MDC1,TIFA,IRF6,SMAD1,SNIP1,SMAD3,KIF1C,IRF7,AGGF1 |
| 7.127e-03 | -4.94 | HULC complex | cellular component | GO:0033503 | 4 | 4 | 19108 | 5553 |
RNF40,RNF20,UBE2B,UBE2A |
| 7.127e-03 | -4.94 | cytoplasmic side of rough endoplasmic reticulum membrane | cellular component | GO:0098556 | 4 | 4 | 19108 | 5553 |
RPL27,RPS29,RPS28,RPS26 |
| 7.129e-03 | -4.94 | EEA1 (early endosome antigen 1) | protein interactions | 8411 | 152 | 57 | 19454 | 5460 |
HSBP1,TMEM237,STX6,ATP6V1A,RAB31,AGR2,H2AC4,PROM1,FCGR2A,RAB22A,TMA16,LAMP3,RAB5C,LAMP2,TOM1,TOLLIP,IGF1R,PCNA,ABCE1,CSTPP1,MOB3C,STX12,RAB4A,MLLT6,RANBP1,TP53,RAF1,PTPRQ,VIRMA,PPP1R3C,BMP1,PLP1,CDC73,LAMTOR1,RPS29,SEC13,SFN,CUL3,LSM8,MARS1,STX7,GRPEL1,ADRB2,USP8,FBXW7,AIF1L,RAB9A,TCEA1,RAB5A,EP300,BAP1,DVL2,VPS18,CFTR,SETD3,SNRNP27,BET1 |
| 7.129e-03 | -4.94 | C5AR1 (complement C5a receptor 1) | protein interactions | 728 | 152 | 57 | 19454 | 5460 |
RMND1,ARL6IP5,SPPL3,GNPTG,ADGRG1,SLC39A10,PTPN1,ARL10,TMEM164,FITM2,FAM241B,SLC38A9,GOLPH3L,SLC25A46,PTDSS1,SLC6A8,B4GALT7,SLC35G2,RINT1,ATP2B4,TSPAN3,GNAI3,SLC35F1,YIPF3,TCAF2,VKORC1L1,RABIF,PARL,GNAI2,TNPO3,ACP2,REEP4,SC5D,RETREG3,SERINC1,GPR89A,SCAMP2,ATP1A3,ENDOD1,SLC30A5,KDSR,CERS2,RER1,SLC35F2,DPH6,TM9SF1,CAV2,FDFT1,LMBRD2,GOLGA5,SIGMAR1,RABL3,SYNGR2,SLC19A2,BET1,FUT8,PAQR3 |
| 7.129e-03 | -4.94 | CIRBP (cold inducible RNA binding protein) | protein interactions | 1153 | 152 | 57 | 19454 | 5460 |
MALSU1,TMPO,CAND1,FZR1,PRNP,USP46,PHB1,AHSA1,TDRD7,SNRNP70,HNRNPA1,COPS5,CSNK2A1,DDRGK1,MOV10,MEPCE,RIGI,NEDD8,HNRNPK,LSM14A,EZH2,CHMP4C,PAIP2B,RAF1,FBP1,E2F4,SMURF1,VIRMA,ESR2,APEX1,TNPO3,PRMT5,PTEN,GTF2F1,CMTR1,MCAT,ARHGAP19,WDR20,ZFAND6,FBXO7,MYC,PAPOLA,CUL3,CUL2,PRMT6,BRIX1,UFL1,HNRNPA0,HNRNPH2,RTN4,SNRPA,BAP1,NGRN,HEXIM1,LXN,CD2AP,WDR77 |
| 7.153e-03 | -4.94 | FBXW11 (F-box and WD repeat domain containing 11) | protein interactions | 23291 | 469 | 156 | 19454 | 5460 |
MRPL57,UBE2D3,HNRNPA0,SKP1,RPS28,HERC3,NGRN,NUP50,SF3B1,GTF2IRD1,MRPS18A,EIF4B,SPINDOC,ATP5F1B,MATR3,MRPL23,PRRC2A,NFKBIA,NFKBIB,MCPH1,MRPL13,SYBU,YWHAZ,FBXW11,ELMO2,RIT1,FAM219A,ELAVL4,HSP90AA1,PFDN4,HNRNPAB,HNRNPC,COPS7A,BAG3,MLF2,MCM4,FOXN2,HNRNPF,KRAS,TNF,HNRNPDL,AHCYL1,CCT8,HNRNPA2B1,PABPC1,RTCB,DNAJB4,RPAP3,PRPSAP1,TRIM21,CDK5,VPS33A,CTNNA2,EZH2,GHR,BTG1,ZNF704,MAX,CSNK1E,NFE2L1,CSTF2T,NUP153,MITF,RPS10,HNRNPL,STK3,RBM5,EED,FKBP4,IKBKB,WDR12,YWHAB,HNRNPD,PFDN5,MAP1S,IFI16,CLPX,CENPW,STK4,CTNNB1,WDR11,NGDN,EIF3D,HNRNPA1,YWHAG,GTF2I,AATF,ZKSCAN1,HNRNPH2,FLCN,BTG2,ZNF326,MRPS34,HECTD1,HNRNPH3,PSMC4,SIPA1L1,PPAT,ARMC6,DAPK1,PHTF2,CTNNA1,CCNF,PTEN,PPP2R5E,CALML5,MRPS28,TRAF7,SH3BP5L,PDCD4,STK11,ATF4,FAM193B,TRIM32,PPP1CC,IFNAR1,KPNA2,THRAP3,NEDD8,RNF115,HUWE1,CNOT7,RIGI,BHLHE40,GARRE1,FAF1,MAP1B,DHX9,NFE2L2,MRPL49,TBC1D4,HBP1,RPSA,TP53,MXI1,MRPS23,NOP9,DKC1,MDM2,UBE2G2,EIF4E2,RPRM,MRPS9,TFE3,SYNCRIP,MCL1,TIAM1,AKAP8L,KPNA1,DNAJC7,ISYNA1,MOV10,NFKB1,TSEN34,MZT2B,COPS5 |
| 7.168e-03 | -4.94 | Frs2-mediated activation | REACTOME pathways | R-HSA-170968 | 250 | 97 | 10285 | 3229 |
FGF7,JAK1,PSMD12,CSF2,SHC3,RAP1A,PSMB9,SPRED2,IL2RA,FGF3,PSME2,PSMD6,HBEGF,NEFL,DUSP10,MAP3K11,PSMB5,PSMA3,PSMC4,PSMD3,PSMB7,JAK2,CRKL,PSMB1,PSMB6,PSMA2,DLG4,BRAP,CSK,PSMA4,FGFR1,IL2,PSMC5,PSMB11,PSMB10,PSMD7,FGF17,SPTBN1,PPP5C,ANGPT1,PSME1,UBB,PPP2R1A,PSMD14,VWF,CUL3,PSMC1,FGF16,IL2RB,LAMTOR3,CAMK2G,PSMB2,PSMD1,PEA15,PSMA6,HRAS,PPP2CB,LAMTOR2,KIT,IL5,SEM1,DUSP1,SHC1,RASGRP3,PSMB4,IL3,RPS27A,SPRED1,PHB1,PSMD4,PSMC3,PSMA1,YWHAB,DUSP6,PPP2R5A,FGF1,IL2RG,SPTAN1,PPP2R5E,PSMB3,PEBP1,MET,PAQR3,FGF23,PSMA5,FGF10,PSMD10,FRS3,SRC,DUSP9,UBA52,FGF22,WDR83,RAF1,RAP1B,MAP2K1,KRAS |
| 7.194e-03 | -4.93 | negative regulation of osteoblast differentiation | biological process | GO:0045668 | 68 | 30 | 18204 | 5365 |
MIR98,PPARG,NOG,MIR30B,CDK6,HAND2,MIR140,VEGFC,GREM1,MIR208A,MIR205,MIR17,MIR214,MIR320A,MIR100,MIR106A,SUFU,SOX9,TNFAIP6,SFRP1,TWIST2,MIR9-1,CITED1,RORB,TWSG1,TNF,FGF23,SMAD3,MIR675,MIR24-1 |
| 7.194e-03 | -4.93 | positive regulation of DNA-templated transcription initiation | biological process | GO:2000144 | 68 | 30 | 18204 | 5365 |
SUB1,JUN,HNF1B,MDC1,ZNHIT1,MED30,TAF2,MED10,MED21,MED11,MED22,GTF2A2,TAF7,TAF10,MED4,TAF11,MED29,NFKBIA,MED31,TP53,MED17,WNT10B,CAND1,MED9,NFKB1,TAF9,MITF,GTF2A1,MED27,MED23 |
| 7.214e-03 | -4.93 | SPRY2 (sprouty RTK signaling antagonist 2) | protein interactions | 10253 | 149 | 56 | 19454 | 5460 |
KDM1A,FXR2,CDC42EP4,PACSIN3,ZDHHC17,CSTB,LCN1,GP9,FRS3,RTF2,NUFIP2,EPHX1,EGLN2,SNX3,NR1H2,MB21D2,CTSB,DYRK1A,FAIM,UBASH3B,CAB39,HEXIM2,UBE2E3,FAM219A,CRMP1,PTPN11,BAG3,CAV3,FBXO7,KRAS,ZBTB16,LASP1,PLSCR1,GNPDA2,TMEM14B,HGS,STK16,SPRY1,GRAP2,NDUFA2,TOP3B,RAF1,PPP2R1A,MLLT6,DDX39A,TRAF2,EGLN3,EIF4E2,DNM2,HRAS,SDHB,TES,TESK1,CBL,MDFI,SIAH2 |
| 7.222e-03 | -4.93 | regulation of leukocyte mediated immunity | biological process | GO:0002703 | 247 | 91 | 18204 | 5365 |
MAD2L2,TYROBP,TICAM1,RIGI,HMCES,IFNB1,SERPINB9,MAVS,IL23A,CD80,CD28,B2M,FERRY3,EXOSC3,TLR9,TNFRSF1B,IL20RB,IL4,SH2D1A,CD46,IFNA2,LILRB4,CD81,TLR3,CD1E,FGR,ICAM1,IL12B,DDX1,IL6,CLEC7A,RSAD2,IL21,IL13,SASH3,RAC2,IL18,HSPD1,FOXP3,IL12A,LILRB1,HSPA8,MICB,CD1A,NECTIN2,TLR4,LEP,STXBP1,SPHK2,BST2,STX7,LTA,FCGR1A,TNFSF13,CLEC12B,NLRP3,TRAF6,KIT,CD1C,CD1B,NDFIP1,CCR2,IL2,CYRIB,KLRD1,ADGRE2,TNF,XCL1,IL10,DUSP22,KLRC2,KMT5B,SHLD1,CX3CR1,TRAF2,VAMP7,TFRC,CD1D,SYK,HMGB1,BCL6,VAMP8,HFE,IL1B,CD40,NCR3,FCGR2B,STAT6,AGER,STAP1,CD226 |
| 7.233e-03 | -4.93 | gluconeogenesis | biological process | GO:0006094 | 49 | 23 | 18204 | 5365 |
CRTC2,FBP2,PC,SLC25A1,G6PC3,LEPR,SLC25A11,CRY1,PGM1,SLC25A10,SDS,SLC25A12,ENO1,PGAM1,SLC37A4,PCK2,ATF4,PPARA,ENO2,MDH1,FBP1,ATF3,PGK1 |
| 7.233e-03 | -4.93 | response to exogenous dsRNA | biological process | GO:0043330 | 49 | 23 | 18204 | 5365 |
RFTN2,RIGI,TICAM1,CAV1,IFNB1,NFKBIA,MUL1,DDX1,TLR3,MAVS,KCNJ8,CGAS,IFNA10,IFNK,IFIH1,PQBP1,RALB,DHX9,IRF3,IFNA13,HCFC2,IFNA2,FLOT1 |
| 7.241e-03 | -4.93 | TGF-beta receptor signaling activates SMADs | REACTOME pathways | R-HSA-2173789 | 34 | 18 | 10285 | 3229 |
CBL,UBE2M,TGFBR2,XPO1,PPP1CB,UBB,RPS27A,FKBP1A,UBA52,PPP1CC,SMAD3,SMAD2,SMURF1,NEDD8,SMAD4,FURIN,STUB1,USP15 |
| 7.241e-03 | -4.93 | positive regulation of cytosolic calcium ion concentration | biological process | GO:0007204 | 163 | 63 | 18204 | 5365 |
HTR2A,ADRA1A,CXCR1,P2RY1,P2RY4,ACKR3,ITGAV,HMGB1,CCR4,CXCR6,PIK3CG,DLG4,SELENOT,CCR6,CXCR4,CCR7,CACNB3,HCRT,PTGFR,SPPL3,CCR3,TAC1,LPAR1,OXTR,PTGER2,BAX,AVPR1B,BAK1,CX3CR1,GNG3,S1PR4,TACR1,CCR5,NPTN,CCL1,CD38,CXCR3,GHRL,SLC8A1,RIC3,PTGER4,CD52,CXCL13,FIS1,CCR2,IL2,JPH4,CCL28,EDNRA,LRP6,JAK2,C1QTNF1,CAV1,CIB2,GPR35,CAV3,MCHR1,SWAP70,LPAR2,PTGER1,FKBP1B,CCR1,CD36 |
| 7.248e-03 | -4.93 | COBL (cordon-bleu WH2 repeat protein) | protein interactions | 23242 | 74 | 31 | 19454 | 5460 |
EP300,FHL3,ZYX,RPA3,RHOU,PACSIN3,KRAS,PPP1CB,CDC42,TOP3B,RPA2,ACTR2,CAPZA2,GSK3A,ESR2,VIRMA,CAV1,TMOD3,HNRNPL,FBXO22,RHOJ,ACTB,YWHAH,YWHAG,ATG9A,AKT3,SFN,VMP1,MAPRE1,RHOB,FBXW11 |
| 7.248e-03 | -4.93 | PPP4R1 (protein phosphatase 4 regulatory subunit 1) | protein interactions | 9989 | 74 | 31 | 19454 | 5460 |
TUBA1A,PPP2R1A,ACTR1A,TRAF2,FBXO42,ATG16L1,PPP4C,CCR1,POLR2C,MTA2,DISC1,GPHN,FASTKD5,CTNND1,HDAC3,XPO1,LDHB,CUL3,MAP4,COP1,DCAF11,TRAF6,DCAF4,SKIC8,SEC61A1,PPP2CB,NDUFB4,CCNF,APEX1,EGLN3,SPTAN1 |
| 7.248e-03 | -4.93 | CNN2 (calponin 2) | protein interactions | 1265 | 74 | 31 | 19454 | 5460 |
STAU1,RIGI,RPA3,ZYX,HSPA8,HNRNPH2,RPA2,RAB4A,PIH1D1,RAF1,CFTR,AKR1C2,TAX1BP1,ACTB,DYNC1I2,MAT2B,EGLN3,ESR2,APEX1,DYRK1A,ACTA2,MTAP,TES,BICD2,BRCA1,PDCD10,CNN3,TRAPPC4,UBE2H,RAB11A,CD81 |
| 7.248e-03 | -4.93 | TRAK1 (trafficking kinesin protein 1) | protein interactions | 22906 | 74 | 31 | 19454 | 5460 |
ENKD1,TOMM20,AKAP1,SAMM50,HGS,CARD19,KLC2,MTX2,MTCH2,TOP3B,TOMM22,ELP3,MGARP,ESS2,DYNLL1,CDC5L,VIRMA,CHCHD3,ZNF664,CDK6,CHCHD6,IFT172,TRAK2,GSK3A,YWHAZ,YWHAB,SFN,UTP6,XPO1,YWHAG,YWHAH |
| 7.262e-03 | -4.93 | lipid metabolic process | biological process | GO:0006629 | 1217 | 397 | 18204 | 5365 |
ISYNA1,ATP5F1A,MIF,YWHAH,CYP26A1,MBLAC2,INPP5K,ACADSB,SOCS4,GDE1,CYP2F1,FITM2,CYP4F8,HACD2,MMUT,MTMR6,SLC25A1,SOCS2,AUH,PTGES,PGAP3,PLA2G4B,SOCS5,CYP2D6,ZMPSTE24,HTRA2,IL4,BRCA1,ABHD12,EPHX1,MTM1,PLPP6,CYP4F22,CAV1,SOCS3,CYP3A43,CRAT,LDAH,ERLIN1,PLCXD3,CAV3,SMPD2,ACOT6,NEU1,OXCT1,SLC25A17,ST3GAL1,GAL3ST1,GDPD3,PTPN22,PLA2G15,SPP1,PEX13,HSD11B1,GSTM2,AMACR,MPDU1,RBP2,SULT1A3,ADTRP,PLSCR3,DPEP1,ST6GALNAC3,OSBP,DHRS7,ATP5F1B,CPT1B,ACADS,PGAP2,CPT2,LIAS,HYCC1,GPX4,DHRS7B,ALG11,PLA2G12A,TECR,HYCC2,BECN1,MVD,CYP1A1,ETNK2,ERG28,HPS6,PRPF19,ILVBL,NR1I2,NDUFAB1,COMT,UGT1A1,CRABP2,TMEM38B,FGFR1,PLPP4,GGTA1,ADORA1,ACSS2,SCD5,LARGE1,PTPN11,IP6K1,INPP4A,PIP4P1,ST3GAL4,SPTSSB,B3GALT1,DHRS3,FADS2,PIGC,HSD17B11,CHST10,HADHA,COX10,PEDS1,CYGB,ACBD7,PGAP4,LEPR,BPNT2,ALG2,TSPO,KDSR,TNFAIP8L3,FAXDC2,SESN2,ADH1A,B4GALT3,GSTA1,HDHD5,SLA2,PPARG,LIPA,ACOX1,SLC16A1,CYP7A1,NSDHL,ST8SIA4,AOX1,B4GALT6,TAMM41,SC5D,NUDT7,PTGDS,CLN8,APOC2,CYP27B1,PLPPR1,PNPLA4,CYP2C18,CYB5R1,TPRA1,PLAAT5,HEXB,FAR2,OSBPL8,PITPNB,CYP4F12,CYP3A5,ORMDL3,BCKDK,CERK,RDH11,MTMR12,PITPNA,FITM1,ABHD5,ITGB8,DPAGT1,ADIPOQ,CYP17A1,GALC,PLAAT3,CYP11B2,PPT1,RDH12,MID1IP1,CFTR,PIP4K2C,ALDH1A3,ACOT8,HSD17B1,PLSCR1,INPPL1,SDR16C5,ELOVL6,LRAT,SPHK2,TAFAZZIN,NFE2L1,FDFT1,PTPMT1,ELOVL1,ECHDC1,GGT7,CYP11B1,MORC2,GGPS1,FUT1,ERRFI1,AGPAT5,LDLR,IMPA2,PAFAH1B2,GAL3ST4,PPARA,ACSL4,CYP27A1,ASMT,ERLIN2,ABHD4,AGPAT1,ABHD6,HEXA,BAX,ADIPOR2,DEGS1,CDIPT,ACAA2,ORMDL1,PLCB1,PCK2,HACD3,MGST2,OCRL,PAFAH1B3,GPX5,DHRS4,CPNE1,ST3GAL2,B3GALT4,HADH,B3GALNT1,SRD5A3,LPCAT3,ETFA,DHRS4L1,PC,PHYH,ELOVL7,WNT10B,PNPLA8,CD36,PIGW,ACP6,NUDT19,PRKAG1,NUS1,SLC35C1,KBTBD2,PCCB,HACD4,FKRP,LBR,SGMS1,CERS6,CYB5R3,GK5,HSD17B10,NPC1L1,PIP4P2,PRKD3,CRYL1,PIK3R3,GSTP1,IAH1,CYP2R1,GPX1,INPP5E,DOLK,XBP1,EHHADH,KIT,PLAA,CRKL,CYP2C8,APOC4,PTEN,PIP5K1A,PLA2G5,PCSK9,VLDLR,B4GALT1,NR1H2,ACER3,SCPEP1,SPTSSA,B3GALT2,AKR1A1,ACACA,UGCG,MTMR2,LRP10,PDSS2,PTGES3,SDR42E1,ADH1B,RETSAT,ABCG2,AIG1,PLCB2,HSD17B8,LEP,UGT2A3,INSIG2,PIK3CG,VAC14,PIK3CA,PAFAH1B1,ELOVL3,PLCL1,FIG4,GPIHBP1,LYPLA2,CYP39A1,GNPAT,SERINC1,DECR2,PIK3R2,ST3GAL5,AGK,PIK3R1,FAH,PIGK,SLC30A5,BSCL2,CCDC3,PIGY,ELOVL4,TLCD3B,PTDSS1,PGS1,AKR1C1,SNX17,AKR1C2,ABHD2,MECP2,HACD1,ETFB,FABP5,B4GALT4,AKR7A2,FGF23,CYP4V2,SACM1L,HMGCS1,LYPLA1,MGST3,GK2,CH25H,CLU,SDS,PCYT1B,CISH,MSMO1,HSD17B6,DPM2,AKR1B1,PRDX6,ADIPOR1,FNTB,LHB,MCAT,ATG4A,GPAA1,CERS2,ABHD16B,GPAM,FA2H,STAR,NPC2,PRKAB1,SGMS2,GSTM4,CD2AP,CYP1B1,ST8SIA5,G6PD,SELENOI,RARRES2,CHKB,VPS54,ACOT13,CYP21A2,ACAT1,MECR,DHRS11,HINT2,HPGDS,CYP2C9,CBR4,PIGA,GLYATL3,RDH10,FUT9,ALOX5AP,HSD17B3,PLP1 |
| 7.271e-03 | -4.92 | negative regulation of cell adhesion molecule production | biological process | GO:0060354 | 14 | 9 | 18204 | 5365 |
MIR222,MIR146A,MIR206,MIR101-1,MIR1298,MIR221,CXCL8,MIR20A,MIR374A |
| 7.271e-03 | -4.92 | N-terminal protein amino acid acetylation | biological process | GO:0006474 | 14 | 9 | 18204 | 5365 |
NAA35,CREBBP,NAA50,NAA16,NAA11,AANAT,NAA15,NAA60,EP300 |
| 7.271e-03 | -4.92 | protein localization to postsynaptic specialization membrane | biological process | GO:0099633 | 14 | 9 | 18204 | 5365 |
LGI1,C1QL2,CACNG3,NETO2,LHFPL4,DLG4,C1QL3,NPTX1,NETO1 |
| 7.271e-03 | -4.92 | negative regulation of long-term synaptic potentiation | biological process | GO:1900272 | 14 | 9 | 18204 | 5365 |
PRNP,TYROBP,FAM107A,CX3CR1,EPHA4,AGER,MIR30B,ADORA1,PTN |
| 7.271e-03 | -4.92 | cardiolipin metabolic process | biological process | GO:0032048 | 14 | 9 | 18204 | 5365 |
PLSCR3,PNPLA8,TAFAZZIN,MECP2,PLA2G5,TAMM41,PGS1,PTPMT1,HADHA |
| 7.271e-03 | -4.92 | regulation of NMDA receptor activity | biological process | GO:2000310 | 14 | 9 | 18204 | 5365 |
IFNG,DLG4,NLGN1,CAPN1,OPRM1,DAPK1,CCR2,CCL2,CRHBP |
| 7.271e-03 | -4.92 | MyD88-independent toll-like receptor signaling pathway | biological process | GO:0002756 | 14 | 9 | 18204 | 5365 |
TLR4,TICAM2,IKBKB,TRAF6,CD274,TLR6,IRF3,TICAM1,PRKCE |
| 7.271e-03 | -4.92 | neurotransmitter receptor localization to postsynaptic specialization membrane | biological process | GO:0099645 | 14 | 9 | 18204 | 5365 |
CACNG3,NETO2,LHFPL4,C1QL2,LGI1,NPTX1,C1QL3,DLG4,NETO1 |
| 7.271e-03 | -4.92 | regulation of toll-like receptor 3 signaling pathway | biological process | GO:0034139 | 14 | 9 | 18204 | 5365 |
TIRAP,HCFC2,FLOT1,TRIM3,SRC,PELI1,CAV1,PTPN22,TNFAIP3 |
| 7.271e-03 | -4.92 | nucleobase-containing compound catabolic process | biological process | GO:0034655 | 342 | 122 | 18204 | 5365 |
MRTO4,DCTD,PDE2A,NUDT9,APOBEC3B,PELO,DNPH1,PPP1R8,RNASET2,OGG1,PABPC1,NUDT3,EXOSC4,NUDT12,DIS3L,APOBEC3A,ENTPD4,FEN1,DICER1,VPS54,CASC3,ZCCHC7,CNOT6,PYM1,BPGM,ACAT1,TRIR,PDE1A,CNOT2,UCP2,MAGOH,SARM1,RBM7,NT5C2,SKIC8,GRSF1,EIF4A3,PNRC1,HNRNPD,LSM2,CNOT6L,PDE12,ETF1,ELOC,DFFA,RNASEH2C,PDE8A,LDHA,DBR1,PGAM1,EXOSC8,RNASEH1,LSM4,DNASE1L1,ISG20,PFKFB2,FKRP,APOBEC3C,HINT1,LSM6,RC3H2,CNOT7,NUDT16,DCTPP1,SMG5,GAPDH,ENTPD3,EIF3E,EXOSC1,NUDT19,YTHDF2,SMUG1,EXOSC3,UPF3B,DXO,SAMHD1,EDC3,NUDT5,PDE9A,DCP2,MTAP,OGDHL,SMG8,WDR82,PGK1,APOBEC3F,LIPA,APOBEC3H,METTL14,NUDT1,MGAT1,NUDT7,NUDT4,FITM2,TENT2,THRAP3,APEX1,NUDT18,RNASE6,SUCLG2,IER3,ENPP4,PGM1,AGO1,CNP,MAGOHB,APOBEC3G,FHIT,NCBP2,DDX5,LSM5,APOBEC3D,PNP,CNOT8,ENO1,HTR2A,PDE7A,SMG9,POLR2G,PDE4B,ENO2,TENT4A |
| 7.282e-03 | -4.92 | URIDINKINASE | prints domains | PR00988 | 4 | 4 | 5227 | 1528 |
UCK2,NMRK1,UCKL1,UCK1 |
| 7.284e-03 | -4.92 | DNA replication | KEGG pathways | hsa03030 | 36 | 20 | 7161 | 2463 |
POLD4,POLE4,FEN1,POLA2,RFC5,RFC3,RFC2,SSBP1,RPA2,RNASEH2C,PCNA,RPA3,RFC4,POLD2,RNASEH1,MCM3,PRIM2,POLE3,MCM4,MCM6 |
| 7.284e-03 | -4.92 | DNA replication | KEGG pathways | ko03030 | 36 | 20 | 7161 | 2463 |
RFC4,PCNA,RPA3,RNASEH2C,MCM6,RNASEH1,POLD2,MCM3,POLE3,PRIM2,MCM4,FEN1,POLA2,POLD4,POLE4,RFC3,RFC2,SSBP1,RPA2,RFC5 |
| 7.288e-03 | -4.92 | Brwd3 (bromodomain and WD repeat domain containing 3) | protein interactions | 382236 | 54 | 24 | 19454 | 5460 |
MRPL24,RPL7,RPL35,LYAR,MRPL13,RPL37A,MRPL53,MRPS25,MRPL18,MRPS35,RFC3,RPL17,RFC2,MRPL20,RPL4,NEDD8,WDR3,RPL3,RPL31,MRPL49,RPL18,MRPL33,APOBEC3D,MRPL47 |
| 7.288e-03 | -4.92 | LTA4H (leukotriene A4 hydrolase) | protein interactions | 4048 | 54 | 24 | 19454 | 5460 |
BAP1,RPA3,SIRT7,PRPF4,HDAC5,HSPA8,IDH1,KRAS,FKBP2,SAR1B,RIGI,RAF1,GH1,SPR,PGM1,RPA2,ARPC3,FBXO32,TAGLN2,TENT5C,ZNF593,CIAO1,AGR2,UBE2H |
| 7.288e-03 | -4.92 | PLCD1 (phospholipase C delta 1) | protein interactions | 5333 | 54 | 24 | 19454 | 5460 |
KRAS,F11R,RALA,RAB11B,RAB39B,FBXL4,FOS,SCG5,HRAS,FBXO3,GATD3,CAPZA2,PNMA2,HGS,CSGALNACT1,SGIP1,PTDSS1,DUSP14,USP6NL,SRFBP1,RALB,KDELR2,SOX2,NTAQ1 |
| 7.288e-03 | -4.92 | MMUT (methylmalonyl-CoA mutase) | protein interactions | 4594 | 54 | 24 | 19454 | 5460 |
GRPEL2,CSTF3,CCDC90B,SSBP1,FAHD1,CYP1A1,SMAD4,AUH,MTG2,NAA50,RALB,MMUT,HSCB,RIGI,CRYZ,THUMPD1,AMACR,RPA3,SLC25A10,HSPA8,PDHA1,MMAA,CD2AP,CNPY3 |
| 7.288e-03 | -4.92 | SERINC2 (serine incorporator 2) | protein interactions | 347735 | 54 | 24 | 19454 | 5460 |
GHITM,SIGMAR1,PTRH2,STOM,CCDC167,SEC62,SEC22B,FUT8,RABL3,HS2ST1,TMEM167B,RER1,HAPSTR1,SLC39A9,NAPA,CNIH4,TMEM42,TMBIM6,ATP6AP2,VKORC1L1,LGALS3,CYRIB,TMEM14A,VAMP3 |
| 7.296e-03 | -4.92 | TM_Fragile-X-F-assoc | interpro domains | IPR019396 | 4 | 4 | 18521 | 5414 |
TMEM185A,TMEM60,TMEM185B,TMEM203 |
| 7.296e-03 | -4.92 | Synaptobrevin/VAMP | interpro domains | IPR016444 | 4 | 4 | 18521 | 5414 |
VAMP2,VAMP1,VAMP3,VAMP8 |
| 7.296e-03 | -4.92 | 3HC_DH_C | interpro domains | IPR006108 | 4 | 4 | 18521 | 5414 |
EHHADH,HADHA,HADH,CRYL1 |
| 7.296e-03 | -4.92 | Ribosomal_uL23/eL15/eS24_sf | interpro domains | IPR012678 | 4 | 4 | 18521 | 5414 |
MRPL23,RPL15,RPL23A,RPS24 |
| 7.296e-03 | -4.92 | FOXP-CC | interpro domains | IPR032354 | 4 | 4 | 18521 | 5414 |
FOXP3,FOXP2,FOXP4,FOXP1 |
| 7.296e-03 | -4.92 | Tyr_Pase-like_PTPLA | interpro domains | IPR007482 | 4 | 4 | 18521 | 5414 |
HACD2,HACD4,HACD1,HACD3 |
| 7.296e-03 | -4.92 | TNFAIP8_sf | interpro domains | IPR038355 | 4 | 4 | 18521 | 5414 |
TNFAIP8L1,TNFAIP8L3,TNFAIP8,TNFAIP8L2 |
| 7.296e-03 | -4.92 | 3-OHacyl-CoA_DH_NAD-bd | interpro domains | IPR006176 | 4 | 4 | 18521 | 5414 |
CRYL1,HADH,HADHA,EHHADH |
| 7.296e-03 | -4.92 | Synaptogyrin | interpro domains | IPR016579 | 4 | 4 | 18521 | 5414 |
SYNGR4,SYNGR1,SYNGR2,SYNGR3 |
| 7.296e-03 | -4.92 | Rab3 | interpro domains | IPR037872 | 4 | 4 | 18521 | 5414 |
RAB3B,RAB3A,RAB3D,RAB3C |
| 7.296e-03 | -4.92 | 3-OHacyl-CoA_DH_CS | interpro domains | IPR006180 | 4 | 4 | 18521 | 5414 |
HADH,CRYL1,EHHADH,HADHA |
| 7.296e-03 | -4.92 | Chemokine_CC_DCCL | interpro domains | IPR034133 | 4 | 4 | 18521 | 5414 |
CCL21,CCL20,CCL25,CCL19 |
| 7.296e-03 | -4.92 | TNFAIP8-like | interpro domains | IPR008477 | 4 | 4 | 18521 | 5414 |
TNFAIP8L2,TNFAIP8,TNFAIP8L1,TNFAIP8L3 |
| 7.296e-03 | -4.92 | DOMON_domain | interpro domains | IPR005018 | 4 | 4 | 18521 | 5414 |
FRRS1L,FRRS1,DBH,MOXD1 |
| 7.297e-03 | -4.92 | RRP1 (ribosomal RNA processing 1) | protein interactions | 8568 | 146 | 55 | 19454 | 5460 |
RPL18,NUPR1,RPN1,CA14,CHMP4C,AURKAIP1,SOX2,MAK16,RAF1,TBK1,E2F4,MEPCE,KRAS,CHCHD2,EFNB1,RPL3,RPL31,MED4,DRG1,ANKRD50,CHCHD1,H2AC4,DDRGK1,IFI16,GRSF1,RIOX2,MDM2,LMNA,RPA2,FAM234A,ATG16L1,TNFSF12,DGCR8,NPTN,HSCB,FBXW7,STAU1,HSPA8,NGRN,RPA3,SIRT7,RIT1,UBE2H,DNAJC19,LMNB1,ANAPC15,MYC,OST4,SMURF1,ESR2,SRPK2,SCN2B,LMBR1L,CCNF,EZH1 |
| 7.324e-03 | -4.92 | response to vitamin | biological process | GO:0033273 | 82 | 35 | 18204 | 5365 |
LIPA,AQP3,BECN1,FOLR2,CYP1A1,LEP,ITGA2,CYP26A1,TSPO,CD40,SPP1,FKBP1B,CDKN2D,SFRP1,IGF1R,PRKCB,MAP1B,VDR,SOD2,BGLAP,TYMS,GPX1,OGG1,CXCL10,STC1,FOLR1,F7,EPO,MDM2,FGF23,SRSF2,IL1A,CYP27B1,LRAT,ALPL |
| 7.335e-03 | -4.92 | regulation of binding | biological process | GO:0051098 | 235 | 87 | 18204 | 5365 |
CPNE1,IFI16,IDE,TFIP11,PPARG,NIBAN2,CSNK2B,DNAJB2,CTNNBIP1,PSEN1,CAMK1,RAN,ADRB3,MET,PLN,SLPI,CYP2D6,TRAF6,SMAD2,MIR148A,CEBPG,SNAPIN,B2M,TERT,HDAC5,SUMO1,NUCKS1,GREM2,RB1,EDF1,MAD2L2,DISC1,JAK2,PAX6,FKBP1A,ZNF593,CLIC2,TNKS,EIF3E,MDFI,CDKN1A,PCSK9,KDM1A,NOG,HEY2,FLOT1,TRIM21,HAND2,ADRB2,STK3,PPP2CB,HMGB1,DPH3,GAS8,NME1,JUN,GMNN,HFE,BAG2,RALB,DKK1,AKT1,TMBIM6,CSNK1E,BAX,ADD1,ROCK1,GTF2F1,TXN,MMP9,TRIM6,ADD2,ACTB,DDRGK1,IFIT2,IGF1,TIAM1,ADIPOQ,SUMO3,ZC4H2,GTF2B,EPHA4,STK4,EIF3D,IFNG,SPPL3,IL10 |
| 7.357e-03 | -4.91 | response to transforming growth factor beta | biological process | GO:0071559 | 172 | 66 | 18204 | 5365 |
EID2,ZYX,MSTN,CITED1,LPXN,MEF2C,CAV1,FOS,SMAD9,SMAD1,CAV2,PDE2A,FURIN,PML,TAB1,BMPR1A,MIR212,CLDN1,TGFBR2,FMOD,FUT8,PAK2,MIR130A,CHST11,CRKL,MIR30A,MIR21,CD2AP,NDP,SOX9,ACVR1,SMAD2,MIR183,IGF1R,HYAL2,FLCN,CX3CR1,CTSK,SFRP1,FERMT2,COL1A2,WNT2,STK16,ROCK1,MIR142,YES1,ACTA2,DLX1,XCL1,ROCK2,DUSP22,TP53,SMAD3,TGFB2,USP15,ITGB8,SMAD5,SMAD4,WNT7A,COL3A1,JUN,ITGB5,PDCD5,ID1,TGFB3,SRC |
| 7.359e-03 | -4.91 | human chr8q11.23 | chromosome location | human chr8q11.23 | 12 | 7 | 26134 | 5823 |
NPBWR1,RB1CC1,OPRK1,TCEA1,PCMTD1,ALKAL1,LYPLA1 |
| 7.377e-03 | -4.91 | ARID2 (AT-rich interaction domain 2) | protein interactions | 196528 | 143 | 54 | 19454 | 5460 |
CD14,SOX9,ELF1,EGR2,SOX2,CBX3,SMARCB1,ASF1A,KPNA2,H3C1,PAX6,EGR1,IRF4,USP2,PIK3R1,HNRNPA1,BCL7C,H2AC4,LHX2,KPNA1,H2AZ1,BRD9,SUMO2,KLF9,ACTL6A,CDK7,LMO3,PPARG,RPA2,KLF3,ELF5,FOS,NLE1,RPA3,SMARCD3,DDIT3,NUP50,NF2,SS18,MYC,HNF1B,AR,IRF1,SMARCE1,STK11,PDCD4,ZNF330,FGFBP1,ACTB,SNRNP40,FBXO22,APEX1,VIRMA,ESR2 |
| 7.377e-03 | -4.91 | TMEM63B (transmembrane protein 63B) | protein interactions | 55362 | 143 | 54 | 19454 | 5460 |
ATP5PO,GP9,RABL3,SLC35F6,TPRA1,SLC19A2,SLC35E1,YIPF5,PHB2,ATP6V1G1,CXCR4,ORMDL1,TSPAN15,ATP5F1E,TMEM185A,TLR9,LMNB1,LGALS8,ATP1A1,SUB1,SCN3B,ATP5F1A,ATP5F1B,LGALS3,VIRMA,VDAC2,RPN1,SLC4A8,MARCKSL1,RAF1,TP53,YIPF3,YIPF4,DDX39A,ERLIN2,SRPRB,FLOT1,GNA11,TSPAN17,LPAR2,TMEM268,HNRNPL,MARCHF4,DERL2,TMPO,SLC38A2,ERLIN1,ATP5PD,CAV1,AIFM1,KCNA2,PHB1,MAGED2,ATP6V1A |
| 7.380e-03 | -4.91 | RBM47 (RNA binding motif protein 47) | protein interactions | 54502 | 202 | 73 | 19454 | 5460 |
NUDT19,OTX2,YTHDF2,RAF1,TOP3B,MRPS33,HNRNPF,RPL17,RPS27A,PFDN1,SFXN1,LSM14A,PABPC1,SLC25A5,TRIM11,MRPS11,CPNE2,ZC3H7A,MRPS26,STAMBPL1,RPS2,PTDSS1,ATP5MG,ACOT8,MOV10,APOBEC3F,HNRNPL,NUP35,NOP9,PEG10,MALSU1,FUBP3,MRPS9,TYMS,PRR3,UBAC2,LARP4B,ZNF326,PICALM,MRPS18A,DYRK2,PRR13,RBMS2,YTHDF1,MRPS7,TMEM209,MIR29A,G3BP2,FADS2,NGRN,MCRIP2,DERL1,SMG5,AKAP1,LSM12,RC3H2,MRPS25,ZCRB1,CASC3,ELAVL2,IGF2BP1,CEP85,HNRNPC,APOBEC3B,MRPL16,SLC25A4,MB21D2,SEC63,PRRC2A,VIRMA,SMAP2,MIR16-1,PHAX |
| 7.386e-03 | -4.91 | PDGFRA (platelet derived growth factor receptor alpha) | protein interactions | 5156 | 378 | 128 | 19454 | 5460 |
SMURF1,STAT5A,MGAT1,PTEN,GXYLT1,HS3ST1,STK11,GRID1,EPHA2,GORASP2,AKT1,PTPN11,CLU,TPST1,LARGE1,NF2,PIK3R2,USP8,ST8SIA4,FTSJ1,NXPE3,CHPF2,GOLGA5,KDELR2,HYAL2,CFTR,FUT8,CDK9,EXTL2,CAV1,B4GALT6,FZR1,SEMA3C,TOP1,GRM1,CGAS,DECR2,OLFM2,CDCA3,SEC23A,CDK6,EXT1,CHID1,C1GALT1C1,BECN1,PRSS12,CDH11,FBXO25,GALNT2,RDH11,TGFBR2,GALNT12,ART5,GLCE,GNAI3,PIK3CA,TFRC,HSPA13,NHERF1,ADAMTS1,MAP2K3,EMILIN3,NDST1,CDK4,TP53,GNB1,NLGN2,STAT1,B4GALT3,B4GALT4,BMP1,OAF,PRMT5,WNT10B,PDF,SCFD1,TAFAZZIN,MYO6,FBXW11,BRCA1,CAV3,RHEB,GGH,BRINP3,MYC,PIK3R3,ITGAV,PACSIN3,TERT,TIMP3,PRSS23,VAPB,EHD1,TOR1B,PXYLP1,OCRL,PCSK9,NDNF,COCH,DNAJB9,LRRC24,SNX2,ADGRG1,DNM2,CBL,RPL23,ST3GAL4,CBR4,PIK3R1,AP1M1,PLPP6,FLOT1,GXYLT2,LAMB2,KIT,EFNB1,JAK1,MYO1B,FHL3,CHST10,CDKN2C,HGS,CRKL,STIM1,CYB5R1,MAK16,B3GNT2,RAF1 |
| 7.386e-03 | -4.91 | SMC3 (structural maintenance of chromosomes 3) | protein interactions | 9126 | 378 | 128 | 19454 | 5460 |
MXD1,CSNK1A1,BET1,EMC1,STAU1,HAND2,CDSN,AZGP1,FTL,SF3B1,HSPA8,HDAC5,EP300,CFDP1,BRCA1,MYC,USP13,CUL3,CUL2,RAB11A,PRPF31,PSMD1,MCM4,CASP4,MATR3,TRIM29,RBBP4,TENT5C,FBXO22,TUBB,ACTB,FRZB,MAD2L2,ESR2,LMBR1L,RPL37A,FOXP3,EZH2,NGB,HDAC11,MTA2,RNF126,MOB3C,SUPT5H,SOX2,TUBA1A,RBBP7,PSMA1,KRAS,GTF3C3,MCM6,PAX6,RAD21,TRIP4,TOP2B,POU5F1,LYZ,LHX2,XPO1,DDRGK1,SUMO2,EGLN3,PHB1,FEZ1,EED,RPA2,HSP90B1,UBE2M,ATG16L1,GTF3C4,KLF12,NF2,MBD3,WFDC5,AATF,RPA3,BAP1,HELLS,RAB9A,MECP2,IVNS1ABP,TBC1D25,UBE2H,SMARCA5,AR,NDN,RALA,COPE,RPGRIP1L,VIRMA,CCNF,ENO1,TUBA1B,CALML5,ALB,PTPMT1,TRIM24,CDK8,TMEM165,DISC1,NUPR1,KBTBD4,CDK4,EEF1A1,MAP1LC3B,H2AX,H3C1,PSMA5,THRAP3,FBXO25,MEPCE,RIGI,MSH6,SFXN1,RING1,BECN1,USP15,COPS5,GAPDH,MAPRE2,CITED1,CDK9,CDC5L,MXI1,CD274,SSU72,EEF1AKMT3,PWP2 |
| 7.387e-03 | -4.91 | soft_tissue-fibrous_tissue_and_uncertain_origin-solitary_fibrous_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-solitary_fibrous_tumour | 19 | 11 | 16828 | 4835 |
MET,KIT,CTNNB1,TP53,FGFR1,TERT,NAB2,HRAS,KRAS,IDH1,SS18 |
| 7.387e-03 | -4.91 | small_intestine-ileum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-ileum-carcinoma-adenocarcinoma | 19 | 11 | 16828 | 4835 |
IDH2,FBXW7,IDH1,PTPN11,TP53,KRAS,CTNNB1,SMAD4,SMARCB1,PIK3CA,STK11 |
| 7.387e-03 | -4.91 | salivary_gland-carcinoma-adenocarcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-adenocarcinoma | 19 | 11 | 16828 | 4835 |
TP53,KRAS,CTNNB1,HRAS,MET,FBXW7,ETV6,PIK3CA,STK11,SMAD4,PTEN |
| 7.400e-03 | -4.91 | UBE2T (ubiquitin conjugating enzyme E2 T) | protein interactions | 29089 | 77 | 32 | 19454 | 5460 |
RNF144B,RPL35A,PRDX2,MBD5,ROCK1,UBE2N,FAAP100,RNF128,TRIM27,BRCA1,STK11,MARCHF5,DEPDC1B,ARL6IP6,OIP5,SLC25A32,HUWE1,NF2,HSPA5,FANCG,XRCC5,RNF167,PCGF2,EWSR1,RDH12,UBE2M,CDK5R1,TPT1,ATP6V1C1,LNX2,GTF2E2,SNRNP27 |
| 7.400e-03 | -4.91 | NQO1 (NAD(P)H quinone dehydrogenase 1) | protein interactions | 1728 | 77 | 32 | 19454 | 5460 |
FUBP3,STUB1,CMBL,CAV1,MOV10,AKT1,BAG3,LYPLAL1,CFL2,AGR2,UBE2D1,ADK,NQO1,UBE2H,TST,FOS,INPPL1,PEBP1,PRDX6,YTHDF1,TRIM26,TNF,POLDIP3,CRYZ,TP53,RAF1,SOX2,ING1,CDC42,NME1,NFE2L2,EZH2 |
| 7.400e-03 | -4.91 | TAF1A (TATA-box binding protein associated factor, RNA polymerase I subunit A) | protein interactions | 9015 | 77 | 32 | 19454 | 5460 |
ANP32A,TP53,TAF1D,DDX39A,VAPB,APOBEC3C,RBM34,RPLP0,NKAPD1,TCOF1,RPL3,KRAS,NPM3,H3C1,STAU1,RPL4,RPL28,MYC,ZCCHC10,RRN3,ZNF668,MECP2,TRIM44,RPL8,PRKRA,TSG101,RPL37A,FGFBP1,SPCS1,LYAR,RPL13A,APEX1 |
| 7.400e-03 | -4.91 | SNX17 (sorting nexin 17) | protein interactions | 9784 | 77 | 32 | 19454 | 5460 |
SNX5,NCR3LG1,XPO1,MOV10,ATG9A,NDUFB6,MYC,MTM1,UMPS,MANSC1,TMEM74,RNF128,COPZ2,POLR3H,LDLR,SLC1A1,PAPSS2,CCNF,HRAS,TSPAN3,RPA2,DUSP1,CDC42,PARM1,RIGI,VLDLR,RABAC1,RAB5A,RLIM,SPATA6,RPA3,RHOU |
| 7.400e-03 | -4.91 | SCPEP1 (serine carboxypeptidase 1) | protein interactions | 59342 | 77 | 32 | 19454 | 5460 |
RANBP1,CCT5,TANK,SETD3,TUBA1A,CD2AP,ACADSB,NCR3,FURIN,BAP1,RPA3,HSPA8,PRDX6,EMP3,STK26,HSCB,STAP1,AP1M1,IMPA2,HSPA5,MARS1,KARS1,XPO1,DAG1,TUFM,NCR3LG1,STK24,SELENOT,CTU1,TUBB,ATP6AP2,ZNF507 |
| 7.408e-03 | -4.91 | Signalling to RAS | REACTOME pathways | R-HSA-167044 | 256 | 99 | 10285 | 3229 |
RALA,CUL3,PSMC1,VWF,IL2RB,LAMTOR3,CAMK2G,FGF16,PSMA6,PEA15,PSMB2,PSMD1,HRAS,PPP2CB,KIT,LAMTOR2,IL5,DUSP1,SEM1,PSMB4,SHC1,RASGRP3,SPRED1,PHB1,PSMD4,IL3,RPS27A,PSMA1,PSMC3,DUSP6,PPP2R5A,FGF1,YWHAB,IL2RG,PSMB3,PEBP1,SPTAN1,PPP2R5E,FGF23,PSMA5,MET,PAQR3,FGF10,SRC,DUSP9,PSMD10,FRS3,RAF1,UBA52,FGF22,WDR83,MAP2K1,KRAS,RAP1B,RALB,PSMD12,FGF7,JAK1,MAPKAPK3,CSF2,RAP1A,SHC3,PSMB9,SPRED2,IL2RA,PSMD6,HBEGF,FGF3,PSME2,NEFL,DUSP10,MAP3K11,PSMC4,PSMA3,PSMB5,PSMB1,PSMD3,JAK2,PSMB7,DLG4,BRAP,CSK,PSMB6,PSMA2,FGFR1,PSMC5,IL2,PSMB11,PSMB10,PSMA4,PSMD7,FGF17,ANGPT1,PSME1,SPTBN1,PPP5C,UBB,PPP2R1A,PSMD14 |
| 7.413e-03 | -4.90 | BTB | smart domains | SM00225 | 174 | 61 | 9717 | 2575 |
KCTD16,IVNS1ABP,KLHL32,KLHL25,KLHL23,KCTD10,KCNC1,KCNS1,KCNG3,KCTD20,ZBTB42,ZBTB39,ZBTB16,KCTD15,BCL6,KCNB1,ZBTB5,KLHL22,SPOP,KLHL1,TNFAIP1,KLHL24,KLHL7,ZBTB38,ZBTB33,KBTBD3,CCIN,RHOBTB1,KLHL12,NACC2,KLHL26,KLHL15,ZBTB45,ZBTB14,KCTD17,ZBTB6,IPP,KLHL3,BTBD10,ZBTB2,ENC1,KCTD3,KCND3,KBTBD2,KLHL9,KCNA3,KCTD9,ZBTB25,ZBTB26,RHOBTB3,BACH1,KBTBD4,KCNA2,RCBTB1,KCND2,SPOPL,ZBTB18,ZBTB17,KCTD12,KBTBD6,KLHL28 |
| 7.421e-03 | -4.90 | DUF758 | pfam domains | PF05527 | 4 | 4 | 17795 | 5224 |
TNFAIP8L2,TNFAIP8L1,TNFAIP8,TNFAIP8L3 |
| 7.421e-03 | -4.90 | DOMON | pfam domains | PF03351 | 4 | 4 | 17795 | 5224 |
FRRS1L,DBH,MOXD1,FRRS1 |
| 7.421e-03 | -4.90 | PTPLA | pfam domains | PF04387 | 4 | 4 | 17795 | 5224 |
HACD4,HACD1,HACD3,HACD2 |
| 7.421e-03 | -4.90 | TIR_2 | pfam domains | PF13676 | 4 | 4 | 17795 | 5224 |
MYD88,TICAM2,TIRAP,SARM1 |
| 7.421e-03 | -4.90 | 3HCDH | pfam domains | PF00725 | 4 | 4 | 17795 | 5224 |
HADH,CRYL1,HADHA,EHHADH |
| 7.421e-03 | -4.90 | FOXP-CC | pfam domains | PF16159 | 4 | 4 | 17795 | 5224 |
FOXP2,FOXP4,FOXP1,FOXP3 |
| 7.421e-03 | -4.90 | 3HCDH_N | pfam domains | PF02737 | 4 | 4 | 17795 | 5224 |
HADHA,EHHADH,HADH,CRYL1 |
| 7.447e-03 | -4.90 | ACTA2 (actin alpha 2, smooth muscle) | protein interactions | 59 | 307 | 106 | 19454 | 5460 |
OR7E24,KLHL3,RBM18,PPT1,EP300,JADE1,DCTN3,NPB,TMEM220,MRPS7,FBXO30,STAU1,UCHL3,NPTN,ZMAT3,SFN,CUL3,CUL2,CREBBP,VMP1,RPS26,OAZ1,LRRC20,SLCO1B3,PNMA1,LGALS3,ACTB,PTPRZ1,CRYGD,ERRFI1,B3GNT2,RPS23,RPL18,RND3,UBE3A,TRIM21,ZYX,OSTM1,IFNG,RPS4X,ETFA,BCL7C,P2RY10,PCNX1,RPL23,DRG1,YWHAB,TNNC2,RHOG,GJA1,MTHFS,SPTAN1,HEXIM1,UBAP1,GSTP1,UBE2M,RPA2,RPA3,BAP1,LRRTM2,ST8SIA4,KDM1A,GCNT3,CFL1,RPL7A,CAP2,CTSD,UBE2H,KCNMA1,SNTA1,ZMAT5,CALML5,GNAO1,TMSB4X,CHRM4,DTWD1,DUSP10,TMOD3,BUB3,FNTB,ACTR1A,TP53,MRPL47,CCT5,UBL4A,NPVF,GPR34,TFCP2,PPP1R1A,RPL17,IL12A,DUSP19,MEPCE,TCP11L2,COPS5,RBM17,PCYT1B,RPL10A,FAM53B,NAA30,TES,ADAM21,NAA11,TMCC2,RPS16,CAND1 |
| 7.458e-03 | -4.90 | cellular response to prostaglandin stimulus | biological process | GO:0071379 | 21 | 12 | 18204 | 5365 |
AKR1C2,P2RY4,PAX6,GNB1,AKT1,GNG2,PTGFR,PTGER2,SFRP1,PRKCE,PTGER4,ACACA |
| 7.458e-03 | -4.90 | response to oxygen radical | biological process | GO:0000305 | 21 | 12 | 18204 | 5365 |
PRDX2,UCP2,CCS,CYGB,NQO1,PRDX1,SOD3,GLRX2,MT3,SOD1,SOD2,TXNRD2 |
| 7.465e-03 | -4.90 | virus receptor activity | molecular function | GO:0001618 | 81 | 35 | 18094 | 5411 |
MOG,CD209,NECTIN2,CLDN6,ITGB5,GPR15,TNFRSF14,LDLR,EPHA2,ITGAV,F11R,CDK1,CLDN1,SLC7A1,CLDN9,PLSCR1,MRC1,CXCR4,RPSA,HYAL2,SLC20A2,CD81,CD4,CCR5,ICAM1,IDE,HTR2A,DAG1,TFRC,ITGA2,CD46,DPP4,CD80,SIVA1,CD86 |
| 7.486e-03 | -4.89 | GOPC (golgi associated PDZ and coiled-coil motif containing) | protein interactions | 57120 | 291 | 101 | 19454 | 5460 |
FBXW7,RAB9A,PML,BAP1,DDX46,ACACA,MANBAL,FGFR1,CFTR,ZSCAN1,TRAM1,PSMC4,JUNB,DUSP10,CHMP5,PSMC5,CRHR1,GRID1,NRP1,RAB2A,VTA1,RAB3B,TOLLIP,TGFBR2,NTRK2,DDR1,FURIN,PSMC3,TFRC,PROK1,ZNF581,BATF,SURF6,CAV1,EPHB6,TMPO,STX6,PPP1R18,CEBPG,EEF1AKMT3,HRAS,STYK1,KPNA1,DNAJC4,CD247,BECN1,LAMP3,PID1,DPP4,MOV10,POLA2,ZBTB5,PSMC1,STX7,RAB5A,DR1,STK26,PCGF2,DDIT3,RTKN,CXCR4,TPD52L1,CRYAB,NACC2,BORCS6,RND2,OTULINL,MORN4,BET1,NUP62,FCHSD2,CLDN3,MOG,DNAJB6,NTRK3,RPS6KA4,LAMTOR1,CDKN3,RAB11A,IMMP2L,IFNG,SSNA1,EPHA4,COX8A,ADRB1,TMT1A,CDKN2C,PTRH2,JUN,RTL6,DIRAS3,ERLIN1,EGLN3,GJA1,FOSL2,RHOG,BTF3L4,RAB5C,FAM174A,LAMP2,ATG9A |
| 7.488e-03 | -4.89 | cellular response to xenobiotic stimulus | biological process | GO:0071466 | 193 | 73 | 18204 | 5365 |
GUK1,GSTO1,CYP1B1,AIP,SLCO2B1,GSTA1,SLCO1B3,GSTO2,CYP2D6,SLCO1A2,ABCC2,NQO1,GSTM4,RAP2A,RBM22,AOX1,UMPS,CYP2C8,CRKL,CYP1A1,EPHX1,SLC29A1,CRYZ,VAV2,NR1I2,CYP2C9,AKR1C1,NFE2L2,PAX6,CBR3,GSTA2,RB1,GSTA4,MEF2C,CYP2C18,ASIC2,IL1B,REN,GSTM2,FMO1,CMBL,CYP3A5,CYP4F12,UGT1A1,CYP26A1,PPP1R12A,CYB5B,SULT1A3,CYP2F1,PDE4B,GLYAT,SULT1B1,FBP1,CXCR4,PRNP,NKX3-1,TP53,TLR3,ABCB1,ABCC5,ADIPOQ,DPEP1,KCNC1,GSTM3,FMO2,POR,TFRC,GSTP1,PCNA,CRHBP,CYP2R1,MYC,NAT2 |
| 7.492e-03 | -4.89 | regulation of reproductive process | biological process | GO:2000241 | 205 | 77 | 18204 | 5365 |
NUPR1,OXTR,ANAPC16,DUSP1,RETN,FZR1,TACR3,CDC20,ASPM,MSX1,NPR2,ANAPC4,SFRP1,CTNNB1,DEFB1,BAX,OVOL1,WEE2,CALR,MAEL,RBPJ,GLRA1,CDC23,IL1A,STK4,CDC16,WDR77,ACVR1C,IGF1,CDC26,STK3,STK11,EAF2,PIWIL2,NKX3-1,SPINK13,CCR6,ANAPC13,SRC,ACVR1B,OVGP1,RAD1,P2RY1,TIMP1,ANAPC15,MIR16-1,VEGFA,YTHDF2,HPGDS,ANAPC11,B4GALT1,PTGDS,PRDX4,CLXN,SEMG2,TPPP2,PRSS37,NPPC,BCL2L1,SYCE3,CNR1,SOD1,AR,MSX2,ANAPC2,CRISP1,SOX9,UBE2B,KIT,TACR1,LHFPL2,PPP2R1A,CDKN1B,RGN,GJA1,PLCB1,PAEP |
| 7.500e-03 | -4.89 | PROTEASOME_ALPHA_1 | prosite domains | PS00388 | 8 | 6 | 12186 | 3388 |
PSMA4,PSMA1,PSMA6,PSMA5,PSMA2,PSMA3 |
| 7.500e-03 | -4.89 | MH1 | prosite domains | PS51075 | 8 | 6 | 12186 | 3388 |
SMAD4,SMAD5,SMAD3,SMAD1,SMAD2,SMAD9 |
| 7.500e-03 | -4.89 | MH2 | prosite domains | PS51076 | 8 | 6 | 12186 | 3388 |
SMAD9,SMAD2,SMAD1,SMAD3,SMAD5,SMAD4 |
| 7.500e-03 | -4.89 | PROTEASOME_ALPHA_2 | prosite domains | PS51475 | 8 | 6 | 12186 | 3388 |
PSMA6,PSMA5,PSMA4,PSMA3,PSMA2,PSMA1 |
| 7.501e-03 | -4.89 | NME2 (NME/NM23 nucleoside diphosphate kinase 2) | protein interactions | 4831 | 174 | 64 | 19454 | 5460 |
ARHGEF39,UFL1,NME4,SKP1,HERC3,SOD1,BAP1,RAB5A,IER2,PPT1,ADSS2,CTBP1,FKBP1A,AKR1A1,GIT2,UBE2M,PPP1R8,SLC48A1,TAGLN2,LDHA,ESR2,RORB,CELA3B,ENO1,PIGK,ENO2,RPS3,MOB4,PPTC7,S100A11,UBE2H,FKBP1B,OAT,LDHB,CFL2,CFL1,VDAC1,PSMA2,SAR1B,FKBP2,NDUFA4,PDIA6,EMC2,HINT1,RUVBL2,ACTR2,NME1,EZH2,PIR,UBE2V1,HYPK,OCRL,NPC2,MDM2,AKR1B1,DSTN,NME2,AK2,PPM1K,HNRNPD,LYZ,EMC4,DDRGK1,HDAC6 |
| 7.501e-03 | -4.89 | ANPEP (alanyl aminopeptidase, membrane) | protein interactions | 290 | 174 | 64 | 19454 | 5460 |
DNAJC3,MTDH,RTN4,EMC1,AIF1L,CLU,HSPA5,CDC42EP4,PGRMC1,SEC22B,LIAS,TOMM22,CNPY3,HSP90B1,TBC1D13,CYB5R3,VDAC2,SEC61A1,SRC,APEX1,ROCK1,PYCR1,GFUS,VEZT,MYC,RALGAPA2,CASP4,GORASP2,SDF2L1,CALU,XPOT,NSDHL,SNAP23,PLCB1,VDAC1,TRIM37,AKAP12,EMC8,SEPHS1,PREB,CCDC47,TM4SF1,ERLIN2,TMEM59,SLC29A1,ACTN4,PCDH19,TMEM165,RPN1,TFRC,PTK7,HACD3,SRPRA,CDCA3,STX5,COCH,NPC2,LMAN1,SLC38A2,ACOT8,HDAC6,OSBPL8,AGPAT1,LRRC57 |
| 7.506e-03 | -4.89 | hormone receptor binding | molecular function | GO:0051427 | 33 | 17 | 18094 | 5411 |
VIP,JAK1,GPHA2,SOCS2,GH1,JAK2,NPPC,PSMC5,PTHLH,PTPN11,GNAO1,CSH1,GNRH2,FABP4,GNRH1,LEP,UCN |
| 7.528e-03 | -4.89 | PUM2 (pumilio RNA binding family member 2) | protein interactions | 23369 | 137 | 52 | 19454 | 5460 |
CNOT2,MOV10,CPEB1,SNRNP70,MED4,MIR221,FUBP3,MIR214,PAIP1,MIRLET7G,NUP35,STRBP,YTHDF2,TP53,APOBEC3D,IKZF5,PAIP2B,MIR17,ILF2,PABPC1,LSM14A,HAPSTR1,ZC3H7A,G3BP1,PSMA5,NUP42,MYC,HNRNPC,ELAVL2,PAIP2,PSMG3,SMAP2,MIRLET7B,TRIM24,SIAH1,PRRC2A,ESR2,PABPC5,RBFOX2,RBMS2,MED23,RPA2,METTL14,LARP4B,NUFIP2,MIR7-1,HECTD1,RNF113A,AKAP1,LITAF,YTHDF1,STAU1 |
| 7.531e-03 | -4.89 | TFB1M (transcription factor B1, mitochondrial) | protein interactions | 51106 | 80 | 33 | 19454 | 5460 |
RPL23A,RPL3,EP300,HSPD1,SNIP1,MRPS17,UFL1,CDC42,MRPL12,TULP3,RAF1,TFB1M,RPL26L1,GRM2,YBEY,FGFBP1,RAC2,PHB1,MALSU1,MRPS23,RPL10,CAND1,RPS16,RHOJ,RHOH,YWHAH,DDRGK1,MYC,GRB10,WWP2,MECP2,SNRNP70,MRPS25 |
| 7.531e-03 | -4.89 | WAC (WW domain containing adaptor with coiled-coil) | protein interactions | 51322 | 80 | 33 | 19454 | 5460 |
RNF20,ZDHHC17,UBE2A,BACH1,EWSR1,RPA3,TFIP11,RHOBTB1,CRKL,CBX3,RPA2,CDK1,NFE2L2,UBE2B,QTRT2,NDE1,RBM12,SUPT5H,TP53,NCBP2,TRAF1,VIRMA,SLAIN2,MB21D2,SNRNP40,TRAF3IP3,VCPIP1,ZBTB38,MOBP,RNF40,AR,EDEM1,CCNB1 |
| 7.531e-03 | -4.89 | MED13 (mediator complex subunit 13) | protein interactions | 9969 | 80 | 33 | 19454 | 5460 |
ENO1,RB1,MED17,POLR2I,ESR2,VIRMA,POLR2B,MED22,AR,STN1,MED29,MED21,MED10,MED27,MED4,TRIP4,NR1I3,MED13L,FBXW7,MED11,MED9,VDR,TOP3B,SUPT3H,POLR1D,RPAP2,MED30,FBXL19,CDK8,MED23,MED31,POLR2G,POLR2C |
| 7.538e-03 | -4.89 | negative regulation of endothelial cell chemotaxis to fibroblast growth factor | biological process | GO:2000545 | 4 | 4 | 18204 | 5365 |
MIR16-1,MIR149,MIR424,CXCL13 |
| 7.538e-03 | -4.89 | CMP biosynthetic process | biological process | GO:0009224 | 4 | 4 | 18204 | 5365 |
UCK2,UCKL1,UCK1,DCK |
| 7.538e-03 | -4.89 | regulation of angiotensin-activated signaling pathway | biological process | GO:0110061 | 4 | 4 | 18204 | 5365 |
PPP3CA,ROCK2,ROCK1,PRKCA |
| 7.538e-03 | -4.89 | positive regulation of Schwann cell migration | biological process | GO:1900149 | 4 | 4 | 18204 | 5365 |
MIR222,RRAS2,MIR221,TIAM1 |
| 7.538e-03 | -4.89 | oxaloacetate transport | biological process | GO:0015729 | 4 | 4 | 18204 | 5365 |
SLC25A11,UCP2,SLC13A5,SLC25A10 |
| 7.538e-03 | -4.89 | positive regulation of mitochondrial ATP synthesis coupled electron transport | biological process | GO:1905448 | 4 | 4 | 18204 | 5365 |
CCNB1,GHITM,CHCHD2,CDK1 |
| 7.538e-03 | -4.89 | exosomal secretion | biological process | GO:1990182 | 4 | 4 | 18204 | 5365 |
COPS5,RAB27A,RAB11A,TSG101 |
| 7.538e-03 | -4.89 | protein localization to secretory granule | biological process | GO:0033366 | 4 | 4 | 18204 | 5365 |
CHGA,CPE,SCG3,SRGN |
| 7.538e-03 | -4.89 | regulation of determination of dorsal identity | biological process | GO:2000015 | 4 | 4 | 18204 | 5365 |
CTNNB1,SOSTDC1,ACVR1,DDIT3 |
| 7.538e-03 | -4.89 | response to glycoside | biological process | GO:1903416 | 4 | 4 | 18204 | 5365 |
CALR,ATP1A1,ATP1A2,ATP1A3 |
| 7.538e-03 | -4.89 | negative regulation of transcription of nucleolar large rRNA by RNA polymerase I | biological process | GO:1901837 | 4 | 4 | 18204 | 5365 |
NOP53,MACROH2A2,MACROH2A1,DEDD |
| 7.538e-03 | -4.89 | regulation of protein localization to endoplasmic reticulum | biological process | GO:1905550 | 4 | 4 | 18204 | 5365 |
AKT1,DDRGK1,RTN4,BTF3 |
| 7.538e-03 | -4.89 | negative regulation of leukocyte tethering or rolling | biological process | GO:1903237 | 4 | 4 | 18204 | 5365 |
CXCL12,CCL25,CCL21,CCL28 |
| 7.545e-03 | -4.89 | glial cell development | biological process | GO:0021782 | 128 | 51 | 18204 | 5365 |
NTRK2,PICK1,DICER1,B4GALT6,EIF2B5,PSEN1,SOD1,CNTN1,TLR2,DRD1,MAP2K1,NCSTN,ILK,EIF2B2,PLP1,PTEN,MECP2,MYRF,HDAC11,MOBP,S100A8,TPPP,WASF3,TLR4,IFNGR1,HRAS,AGER,CDK6,CLU,AKT2,CDK5,IL1B,MIOS,SLC25A46,LAMB2,AKT1,DAG1,ID4,NKX6-2,FA2H,EIF2B3,CNTNAP1,GPM6B,LPAR1,TNF,CERS6,KRAS,ASPA,IFNG,RAF1,KCNJ10 |
| 7.545e-03 | -4.89 | GIMAP1 (GTPase, IMAP family member 1) | protein interactions | 170575 | 43 | 20 | 19454 | 5460 |
TMEM45B,REEP4,MGST3,PTGES,RMDN3,HSD17B11,ELOVL4,TMX2,JAGN1,TMEM14B,ZDHHC15,MFSD14B,STX1A,STOM,FCGR2A,FAM174A,SCN3B,TMEM101,BLCAP,TM4SF19 |
| 7.545e-03 | -4.89 | Bub1b (BUB1B, mitotic checkpoint serine/threonine kinase) | protein interactions | 12236 | 43 | 20 | 19454 | 5460 |
CDCA3,ANAPC2,ANAPC16,MIS12,IMPACT,SEC63,NUF2,MAD2L1,CDC20,BUB3,FZR1,ZMAT3,ANAPC13,NDC80,CDC26,SPC24,DSN1,CDC16,ANAPC4,CDC23 |
| 7.545e-03 | -4.89 | SNUPN (snurportin 1) | protein interactions | 10073 | 43 | 20 | 19454 | 5460 |
SNRPE,RNF126,USP15,XPO1,SNRPB,SNRPN,PPP1R8,SNRPG,SNRPB2,SMN1,RPL17,GCNT3,KRAS,SNRPD3,SNRPA1,PAFAH1B2,SNRPD1,RAN,XRCC5,ENO2 |
| 7.545e-03 | -4.89 | SERPINB6 (serpin family B member 6) | protein interactions | 5269 | 43 | 20 | 19454 | 5460 |
PLG,HNRNPL,SUMO2,PRNP,OPTN,RPA3,F10,FBXO32,PTEN,SOSTDC1,EMC2,RPA2,ACACA,UBE2H,PIH1D1,MYC,F2,EMC4,PPIB,TULP3 |
| 7.545e-03 | -4.89 | BET1L (Bet1 golgi vesicular membrane trafficking protein like) | protein interactions | 51272 | 43 | 20 | 19454 | 5460 |
GOSR1,YKT6,CAV1,RAB18,TMT1A,VAMP3,STX5,RAB5A,STX18,NRSN1,NAPA,HNRNPD,SCFD1,SEC22B,BET1,VAMP5,GOSR2,RAB2A,LAMP2,OTULINL |
| 7.545e-03 | -4.89 | MMP7 (matrix metallopeptidase 7) | protein interactions | 4316 | 43 | 20 | 19454 | 5460 |
CNOT6L,RANBP10,CD151,CNOT7,PLG,TFPI,MMP9,MKLN1,ZBTB33,CNOT6,GID8,MAEA,GID4,SERPINA1,ARMC8,SPP1,HBEGF,CNOT8,FASLG,CNOT2 |
| 7.545e-03 | -4.89 | P2RX4 (purinergic receptor P2X 4) | protein interactions | 5025 | 43 | 20 | 19454 | 5460 |
EIF2B5,EIF2B2,EMC1,PGAP4,OPRL1,HS2ST1,TNPO3,LRP10,GLT8D1,CYBC1,ARMCX3,EIF2B3,FGFR1,GALNT1,DNAJC19,FDFT1,COQ8B,KCNJ8,FAM20B,CSGALNACT2 |
| 7.545e-03 | -4.89 | ARHGAP27 (Rho GTPase activating protein 27) | protein interactions | 454752 | 43 | 20 | 19454 | 5460 |
CPSF1,MRPL53,MRPS28,GANAB,HSPE1,WASL,PRDX2,CAND1,CHCHD2,BUB3,PRDX4,PRRC2A,RPS29,CPSF2,CD2AP,PDHA1,CAPZA2,NME2,ATP5PO,RPN1 |
| 7.547e-03 | -4.89 | regulation of organ growth | biological process | GO:0046620 | 102 | 42 | 18204 | 5365 |
FXN,TOMM70,NOG,HEY2,FOXC2,MIR590,SOD1,PPARA,PROX1,STK3,FGFR1,MIR208A,SASH3,RUNX1,MIR548C,G6PD,AKT1,SAV1,MIR222,PI16,CDK1,MIR25,RGS2,WNT2,VGLL4,MIR1-1,GSK3A,IL7,MEF2C,CAV3,IGF1,FOXP1,MIR873,SLC6A4,PTEN,DUSP6,BMPR1A,STK4,MIR204,MAEL,PARP2,RBPJ |
| 7.554e-03 | -4.89 | central nervous system development | biological process | GO:0007417 | 995 | 328 | 18204 | 5365 |
BOK,ASPA,KRAS,HMX2,RNF103,CERS6,SLC6A3,NEUROD6,EIF2B3,TOX,OXTR,FGF10,CTNNB1,RBBP4,SLC1A1,PCDH9,RERE,GSTP1,SLC1A2,MIOS,DKK1,SPOCK1,CA10,HOXB1,PEX13,NDNF,IL1B,GAS8,ELAVL4,SOX2,WNT7A,CLP1,COL3A1,NPY,PROX1,FKRP,WASF3,CEND1,VPS4B,SEMA5A,TPPP,DDIT4,KLHL1,VLDLR,MATCAP1,KDM1A,NRP1,RPGRIP1L,LRP6,CKB,ATP2B4,TTC8,SMAD1,NCKAP1,MCPH1,PTEN,ROGDI,TUBA1A,CDK5RAP3,MAP2K1,TMX2,FZD3,TNR,MTF1,RHEB,SOX9,CTNNA2,ANP32B,ATP5PF,GRIA1,LMO4,ATP1A2,BRINP3,CRKL,CBLN1,NAPA,TGFBR2,EPHA4,DLX1,UBE3A,COX7B,KCNC1,IMMP2L,FOXP1,THOC6,GPM6B,DNAJC30,BGLAP,CDC42,GPR17,ASPM,SOX21,PADI2,COX6B1,UBB,IFT172,BAX,HAPLN2,SLITRK5,CREB1,NDST1,CSK,IGF1R,ID4,AKT3,FOXP3,ATP6AP2,FUT1,GRIK1,OTX2,KCNA2,ACTL6A,YWHAH,RAB18,HNF1B,PPP1R17,CDK5R1,IFNGR1,EMX2,STK3,GPR37L1,KDM4B,RFX4,EED,NEUROD2,SHC3,WDR37,COQ8B,SSBP3,TYROBP,PAX6,SIN3A,DRP2,NDUFS3,SLC32A1,CMA1,PTPRZ1,ZBTB16,WWP1,MYD88,PLCB1,OPHN1,HTRA2,RTN4,HSPA5,ECRG4,TULP3,EGR2,PSEN1,UQCRQ,SEMA4C,KCNJ10,PPT1,SCYL2,RBPJ,TWSG1,SPTBN1,ACTB,SLC2A1,TNF,RBBP7,SLC7A11,ATG16L1,CNTNAP1,GIT2,FA2H,WNT2,HNRNPD,TAGLN3,CDKN2C,NKX6-2,TMEM108,MSX1,CX3CR1,CXCL12,MACROH2A2,KLK6,CDK5,PHACTR1,LBX1,TOP2B,CORO1C,CLU,AGER,DUSP10,CXCR4,NOG,S100A8,FCGR2B,ELP3,MOBP,SPHK2,MPST,POU1F1,NDN,DRGX,BMPR1B,JRKL,IGF2BP1,KCNA3,DISC1,SYNGR3,UGP2,ZNF365,PLP1,CITED1,FGF13,ASIC2,H2AX,FBXW11,DRD1,TRA2B,TLR2,G6PD,POU3F4,FXR2,MARCKSL1,NDP,CNTN1,LDB1,NEFL,ZDHHC16,BPGM,NEUROG2,UFM1,FEZ1,NPTX1,CDH11,POMT2,ALDH1A3,INA,CLDN3,NHEJ1,VPS54,BMERB1,STK4,HTR5A,ZC4H2,TP53,IFNG,MAP1S,PAFAH1B1,BRINP1,ATP5PB,LPAR1,DYNLL1,TMEM14B,GNPAT,CNP,HOXB8,P2RY12,SCN1B,LAMB2,LARGE1,CDK20,BRINP2,SRC,SLC25A46,HSPA8,ATXN1L,EXT1,ACKR3,FGFR1,SRSF1,MGARP,SERPINI1,PDSS2,RAD1,HELT,COMT,NDE1,CDK6,TLR4,SLC4A10,LEP,GNB4,SELENOP,SMG9,MACO1,PTPN11,HDAC11,BMPR1A,MTPN,MYRF,RRM1,MKKS,MECP2,EFHC1,NR4A2,CLN8,MNAT1,PTS,SOX3,SLC6A4,S100B,TAL2,EIF2B2,LHX2,ATAT1,NF2,EZH1,EZH2,CHRNB2,MOG,UPF3B,FZD6,ADGRG1,SLC38A2,NCSTN,CAPG,SEMA7A,AMIGO1,SUFU,FOXP2,CCDC134,NR2E1,BTG2,RAN,NR0B1,TRNP1,EIF2B5,METTL14,B4GALT6,SOX14,NTRK2,EMX1,FZD4,ARCN1 |
| 7.555e-03 | -4.89 | negative regulation of mononuclear cell migration | biological process | GO:0071676 | 36 | 18 | 18204 | 5365 |
CCL2,WASL,MIF,CD200R1,MMP28,PLCB1,AKT1,DDT,MIR24-1,EMILIN1,CCN3,PADI2,DUSP1,MIR146A,GREM1,STAP1,ADTRP,CD200 |
| 7.569e-03 | -4.88 | transcription coactivator activity | molecular function | GO:0003713 | 271 | 100 | 18094 | 5411 |
TRIP4,ACTL6B,CBFB,APEX1,TRIM24,SETD4,ELK1,HYAL2,TRIM22,HMGB1,CTBP1,LDB1,MED17,TRIM52,TRIM21,EDF1,ARL2BP,LMO2,CREBBP,SETD3,MED4,CTNNB1,MTA2,UBE2L3,TAF9,DHX9,RUVBL1,ACTL6A,YAF2,KDM1A,VGLL2,DYRK1A,PCBD1,USP16,RERE,BRCA1,TRIM5,PRMT2,SSBP3,MTA3,HMGA1,BIRC2,CCAR1,TADA3,SMARCD3,WBP2,TAF5L,MED27,SUB1,SERTAD2,ACSS2,TADA1,EP300,UBE3A,LMO3,HCFC2,ZBED1,MED21,PRKCB,NIBAN2,SS18,AIP,NUPR1,TAF11,CITED1,NME2,BCL9,THRAP3,ACTN4,CNOT6,NUCKS1,BUD31,RAP2C,ENY2,SUPT3H,RNF20,BCL10,COPS5,NFKBIB,JUP,TRIM62,TRIM37,CD274,SUPT7L,SMARCB1,MED23,MTDH,TGFB1I1,TRIM8,TRIM15,PQBP1,WDR77,SMARCE1,DYRK1B,JADE1,TRIM32,MED30,IRF4,RNF14,TRIM27 |
| 7.575e-03 | -4.88 | autophagosome | cellular component | GO:0005776 | 115 | 46 | 19108 | 5553 |
PIP4K2C,RAB2A,VPS33A,ATG16L1,TRIM32,TBC1D25,ENTPD4,HSPA8,C9orf72,MYO6,TP53INP2,CHMP2A,MAP1LC3A,CHMP4C,TMEM74,SQSTM1,ATG9A,CHMP1A,TM9SF1,ATP6AP2,TBC1D17,BECN1,RAB23,MAP1LC3B,OPTN,NRBF2,TEX264,SNAP29,TAX1BP1,LAMP2,TBC1D5,VMP1,VPS18,GABARAP,CHMP2B,STX17,CHMP1B,TP53INP1,GABARAPL1,SH3GLB1,CHMP5,GABARAPL2,TICAM1,VPS16,RB1CC1,TRIM21 |
| 7.598e-03 | -4.88 | NUP88 (nucleoporin 88) | protein interactions | 4927 | 134 | 51 | 19454 | 5460 |
KRAS,G3BP1,NUP107,TRIM37,IMMP2L,VPS33A,GLE1,NUPR1,TP53,RANBP1,NUP153,TRIM62,CAND1,CNTROB,RBM42,NUP35,ETV6,FBXO32,KRT8,DCAF11,IFI16,XPO1,KDM1A,G3BP2,RPA3,SIRT7,RNF113A,RPA2,TFIP11,DNAJC24,NUP62,ATG16L1,BORCS6,ESR2,DES,DYRK1A,CCNF,LMBR1L,RAN,ANAPC2,PHF21A,CIRBP,BICD2,XPOT,COP1,RIT1,MAPRE1,MYC,CUL3,CUL2,MCM3 |
| 7.599e-03 | -4.88 | adh_short | pfam domains | PF00106 | 44 | 21 | 17795 | 5224 |
HSD11B1,RDH11,CBR3,SPR,DHRS3,HSD17B6,DHRS7,DHRS7B,HSDL2,KDSR,SDR16C5,HSD17B10,HSDL1,HSD17B3,HSD17B1,RDH12,DHRS11,DHRS13,HSD17B11,DHRS1,RDH10 |
| 7.616e-03 | -4.88 | DTD1 (D-aminoacyl-tRNA deacylase 1) | protein interactions | 92675 | 27 | 14 | 19454 | 5460 |
TNNC2,DTD1,TOPBP1,KRAS,CAMKV,CYP1A1,NEK2,CDC7,CSNK2A1,MSX2,CSNK1E,RAF1,KLHL24,ANKMY2 |
| 7.616e-03 | -4.88 | CMIP (c-Maf inducing protein) | protein interactions | 80790 | 27 | 14 | 19454 | 5460 |
HNRNPL,SPPL3,TRIM54,RHOJ,FBXW7,RIGI,INPPL1,GNA11,TSR2,P2RY1,ZC4H2,RHOB,GNAQ,PIK3R1 |
| 7.616e-03 | -4.88 | RMDN2 (regulator of microtubule dynamics 2) | protein interactions | 151393 | 27 | 14 | 19454 | 5460 |
LMNA,VAPB,YWHAB,STX1A,SLC25A46,AGTRAP,MTCH2,VEZT,ARMC6,TOMM20,RDH10,AKAP1,HSD17B11,RMDN3 |
| 7.616e-03 | -4.88 | EIF2S3B (eukaryotic translation initiation factor 2 subunit gamma B) | protein interactions | 255308 | 27 | 14 | 19454 | 5460 |
PIH1D1,RPS11,RPS5,ZNF326,PSMD14,EZH2,CFTR,SOX2,WWP2,CDC123,SAP18,EIF2S1,RPS24,SRSF1 |
| 7.616e-03 | -4.88 | RGL2 (ral guanine nucleotide dissociation stimulator like 2) | protein interactions | 5863 | 27 | 14 | 19454 | 5460 |
HRAS,CCDC90B,RAP1B,KRAS,RALA,KPNA2,EEF1G,RIGI,TOP3B,YWHAG,YWHAH,GORASP2,CRMP1,YWHAB |
| 7.616e-03 | -4.88 | COA6 (cytochrome c oxidase assembly factor 6) | protein interactions | 388753 | 27 | 14 | 19454 | 5460 |
AIFM1,SFXN1,COX4I1,ATP5PF,DSTN,PMAIP1,KRAS,FZR1,COA1,PRNP,COX14,PLGRKT,TRAF6,RIT1 |
| 7.616e-03 | -4.88 | PLEKHG4B (pleckstrin homology and RhoGEF domain containing G4B) | protein interactions | 153478 | 27 | 14 | 19454 | 5460 |
CDC42,DYRK1B,PIK3R1,MAT2A,CUL3,SNRPE,CSTA,ATP5IF1,FHL3,ZYX,MRPS7,SURF6,HNRNPL,LYAR |
| 7.616e-03 | -4.88 | LYRM2 (LYR motif containing 2) | protein interactions | 57226 | 27 | 14 | 19454 | 5460 |
TBK1,MTRF1,CUL3,NDUFAB1,KLHL22,MANBAL,CLIC2,MSRB3,MRPL13,HINT1,ACADS,GUK1,LYRM2,POLDIP2 |
| 7.616e-03 | -4.88 | TANGO2 (transport and golgi organization 2 homolog) | protein interactions | 128989 | 27 | 14 | 19454 | 5460 |
PRDX1,GAPDH,PPIF,CFL1,ADSS2,PNPO,HSPD1,SOD1,GNPDA1,LCMT1,PRNP,HNRNPL,G6PD,APEX1 |
| 7.616e-03 | -4.88 | H6PD (hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase) | protein interactions | 9563 | 27 | 14 | 19454 | 5460 |
PTDSS1,CCL3,GGH,SDF2L1,RPA2,TAFAZZIN,RPA3,PTGDS,CSH1,DNAJB9,HNRNPL,VIRMA,SKP1,HSPA5 |
| 7.616e-03 | -4.88 | ANKRD12 (ankyrin repeat domain 12) | protein interactions | 23253 | 27 | 14 | 19454 | 5460 |
TADA3,HNRNPD,CDK4,COPS5,YES1,TRIM37,HNRNPL,HDAC3,RIGI,VIRMA,GNB4,PHYHIP,GLIPR2,CDK6 |
| 7.616e-03 | -4.88 | ICAM3 (intercellular adhesion molecule 3) | protein interactions | 3385 | 27 | 14 | 19454 | 5460 |
MSN,ZBTB16,ACTB,PRKCQ,RIGI,CLDN4,TSPO,EDDM3B,FUT8,DDX39A,SEC22A,CD209,SMCO4,SFTPC |
| 7.616e-03 | -4.88 | NKIRAS2 (NFKB inhibitor interacting Ras like 2) | protein interactions | 28511 | 27 | 14 | 19454 | 5460 |
GFOD1,PAX6,SMN1,MAD2L2,APEX1,EGLN3,NFKBIA,DUSP6,GADD45A,NFKBIB,CCNF,GFOD2,RALGAPA2,CBLN4 |
| 7.630e-03 | -4.88 | blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | blastic_plasmacytoid_dendritic_cell_neoplasm | 67 | 29 | 16828 | 4835 |
PTEN,IKZF2,FGFR1,FBXW7,JAK2,ETV6,TP53,KIT,MET,SMAD4,IDH1,KRAS,UBE2G2,EZH2,MYD88,SMARCB1,PIK3CA,IDH2,AKT1,PTPN11,SRSF2,CTNNB1,RB1,GNA11,SF3B1,RUNX1,GNAQ,STK11,HRAS |
| 7.640e-03 | -4.87 | FLNC (filamin C) | protein interactions | 2318 | 218 | 78 | 19454 | 5460 |
FURIN,CHMP4C,PLS3,GNG3,TOP3B,RAB8B,PSMD12,TRIM63,HSD17B10,ADRA1A,PABPC1,PSME1,CCT8,NUDT5,AGR2,H2AC4,IKBKB,MFN1,SIAH2,PPIB,PLEKHO1,PSMD3,KARS1,CCT7,LRRC61,PRNP,TES,GJA1,PHB1,KCND2,AIFM1,RTF2,SLC25A3,PRKCA,METTL14,RPA2,CFTR,UQCRC1,CDC42,PIP5K1A,SAP30BP,PSMC4,WDR77,HSPA5,MARS1,PIAS1,STAU1,MYOZ3,EEF1G,SRM,SNX24,TNFAIP1,MTDH,TXNL1,HSPB2,HSPA8,SIRT7,PML,BAP1,RPA3,INPPL1,CDC73,FBXW11,BRCA1,USP14,HMGCS1,CUL2,PSMA4,CUL3,MYC,MAT2A,DYRK1A,CTTNBP2NL,RAPGEF5,ATP5F1B,TRIM54,PHAX,ENO1 |
| 7.640e-03 | -4.87 | ARF5 (ADP ribosylation factor 5) | protein interactions | 381 | 218 | 78 | 19454 | 5460 |
RHOBTB3,MCM3,GORASP2,ARHGAP21,LDHB,RAB11A,CSK,SERPINH1,EPHA2,SLC38A1,ARFGAP3,LAMTOR1,FAS,BLVRA,VDAC2,ARF1,DUSP3,SH3BP4,APLNR,LDHA,COPE,DUSP22,SNRNP27,TIMMDC1,PIP5K1A,GINM1,ACACA,ARCN1,WWP1,GOLGA5,GHITM,ZCCHC17,RPA2,LMNA,CTBP1,LDHAL6B,AKAP1,EP300,ARFIP1,TMEM263,RPA3,DUSP9,GRPR,SLC15A1,STAU1,PPP2R3A,SLC31A1,FAM174A,DPP4,CDH13,AGR2,SLC2A1,STX5,HSD17B11,DUSP6,KCNA2,CDC5L,MARCHF4,RPL35A,ARF6,FAF2,NECAP2,TUBA1A,RAF1,FBP1,EZH2,RPN1,PC,PRPS1,DUSP19,RNF26,IMMP2L,DUSP21,ARF4,ETFA,CBX7,SRPRB,ARL5B |
| 7.643e-03 | -4.87 | B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3) | protein interactions | 10331 | 83 | 34 | 19454 | 5460 |
B3GNT2,CLSTN3,PGRMC1,CLEC2B,TUBA1A,CNPY3,HYAL2,DSTYK,GALNT1,GHITM,SFTPC,CHPF2,PCYOX1L,GPAA1,GALNT12,ERLEC1,ITGAV,HSPA5,LRFN3,CSGALNACT2,CHPF,SLC30A5,HFE,SDF2L1,ATP1A3,DCAF11,COQ8A,PIGK,RMDN3,SLC30A7,CHID1,AMIGO1,OS9,SELENON |
| 7.643e-03 | -4.87 | FTO (FTO alpha-ketoglutarate dependent dioxygenase) | protein interactions | 79068 | 83 | 34 | 19454 | 5460 |
CNDP2,CTSA,NHERF1,RPA2,GPX7,ZMYM3,TULP3,EEF2,TNPO2,CARTPT,PGAP2,GNG13,MVD,RIGI,ZC3H15,RPA3,CDKN2AIP,CLP1,OSGEP,CKB,GNG2,SHC3,TYW3,ZMAT3,MTPN,DIRAS2,LDHB,NFYA,MAD2L2,BCCIP,PRNP,LDHA,SPRED2,CCNF |
| 7.643e-03 | -4.87 | TUT4 (terminal uridylyl transferase 4) | protein interactions | 23318 | 83 | 34 | 19454 | 5460 |
CSK,MYC,MOV10,CUL2,MIR143,CUL3,COPS5,MIR98,DCAF4,MIR363,IGF2BP1,UBE2H,CCNF,FUBP3,SMAP2,TRIM24,DCUN1D1,HNRNPL,CAND1,MIRLET7G,MIRLET7D,EGLN3,APEX1,YTHDF2,CAPN2,EXD2,LSM14A,MIRLET7I,TIFA,BAG2,FXR2,STAU1,MIRLET7C,RIGI |
| 7.643e-03 | -4.87 | UBE2C (ubiquitin conjugating enzyme E2 C) | protein interactions | 11065 | 83 | 34 | 19454 | 5460 |
CXCR1,BAG3,COPS5,TRIM29,TAGLN2,PSMD4,TTC9C,FZR1,CDC20,MAD2L1,PSMB5,UBE2S,ENO2,STUB1,ANAPC2,UBASH3B,TYMS,UBE2B,PCLAF,RNF7,RAG1,ZRANB2,UBE2V1,PCGF3,ANAPC11,UBE2D3,PSMA5,AHCYL1,SAR1B,RNF167,PPM1G,RNF133,HECTD3,TRIM21 |
| 7.643e-03 | -4.87 | UTP6 (UTP6 small subunit processome component) | protein interactions | 55813 | 83 | 34 | 19454 | 5460 |
CDC5L,RHOJ,S100A6,LMBR1L,RIT1,CCDC85B,ATG7,XPO1,UBXN6,KXD1,IFI16,MYC,CDC123,AATF,BCL6,PTGES3,STAU1,KRAS,GHRL,GPSM3,SIRT7,RPA3,SNIP1,EIF1AD,NUPR1,GPBP1L1,TFIP11,HDAC11,RPA2,GPX7,CARTPT,SOX2,ESS2,TANK |
| 7.644e-03 | -4.87 | BRIX | prosite domains | PS50833 | 6 | 5 | 12186 | 3388 |
BRIX1,RPF2,PPAN,RPF1,IMP4 |
| 7.644e-03 | -4.87 | ELO | prosite domains | PS01188 | 6 | 5 | 12186 | 3388 |
ELOVL7,ELOVL4,ELOVL3,ELOVL6,ELOVL1 |
| 7.646e-03 | -4.87 | Sqstm1 (sequestosome 1) | protein interactions | 18412 | 17 | 10 | 19454 | 5460 |
DNAJB2,TBK1,BMPR1B,SMAD3,C9orf72,MAP1LC3A,ACVR1,SMAD4,SMAD2,SMURF1 |
| 7.646e-03 | -4.87 | Ttll12 (tubulin tyrosine ligase-like family, member 12) | protein interactions | 223723 | 17 | 10 | 19454 | 5460 |
PSRC1,EIF4B,MRPL50,MRPS21,CBX3,DNAJB4,HSPB8,OTUD6B,KLHL7,CCNF |
| 7.646e-03 | -4.87 | CDC42EP3 (CDC42 effector protein 3) | protein interactions | 10602 | 17 | 10 | 19454 | 5460 |
CDC42,SEPTIN7,CDC42EP3,SEPTIN6,ARL15,ARL6,HNRNPL,COPE,DAPK1,UMPS |
| 7.646e-03 | -4.87 | MFSD10 (major facilitator superfamily domain containing 10) | protein interactions | 10227 | 17 | 10 | 19454 | 5460 |
OTULINL,CLK1,CYP2C18,RPN1,NPSR1,PDE2A,ESR2,PLD3,SRPK2,RIGI |
| 7.646e-03 | -4.87 | STK32A (serine/threonine kinase 32A) | protein interactions | 202374 | 17 | 10 | 19454 | 5460 |
CCT5,CCT8,HSP90AA1,CCT7,HSP90AB1,KRAS,SPPL3,CCT2,PRKCE,TCP1 |
| 7.646e-03 | -4.87 | MCF2 (MCF.2 cell line derived transforming sequence) | protein interactions | 4168 | 17 | 10 | 19454 | 5460 |
GNB1,HSP90AA1,SAP18,NEFL,RHOG,HSPA8,CDC42,TP53,ERCC3,STUB1 |
| 7.646e-03 | -4.87 | DPAGT1 (dolichyl-phosphate N-acetylglucosaminephosphotransferase 1) | protein interactions | 1798 | 17 | 10 | 19454 | 5460 |
MFSD3,KRAS,RIT1,LSM8,APEX1,CUL3,ST3GAL2,OLFML3,CD1E,HSPA8 |
| 7.646e-03 | -4.87 | FLRT3 (fibronectin leucine rich transmembrane protein 3) | protein interactions | 23767 | 17 | 10 | 19454 | 5460 |
CALR,RAF1,DDX39A,MBLAC2,GJA1,RHOG,KRAS,ARF6,FGFR1,CAV1 |
| 7.646e-03 | -4.87 | SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase) | protein interactions | 51091 | 17 | 10 | 19454 | 5460 |
TNFAIP3,RPLP1,XPO1,SOX2,LZTFL1,RNASEL,MTMR2,RBPJ,COP1,HEXIM1 |
| 7.646e-03 | -4.87 | CYP3A4 (cytochrome P450 family 3 subfamily A member 4) | protein interactions | 1576 | 17 | 10 | 19454 | 5460 |
UBE2D1,CYP3A5,POR,UGT1A1,PRKCA,PGRMC1,CYP2C9,STUB1,CYB5A,HSPA8 |
| 7.646e-03 | -4.87 | BMP8A (bone morphogenetic protein 8a) | protein interactions | 353500 | 17 | 10 | 19454 | 5460 |
TAFAZZIN,SDF2L1,GPIHBP1,PI15,BRINP1,TMEM87A,NXPH3,CFC1,DDX39A,GGH |
| 7.646e-03 | -4.87 | DPP6 (dipeptidyl peptidase like 6) | protein interactions | 1804 | 17 | 10 | 19454 | 5460 |
CSGALNACT2,NUDT9,KCND2,TP53,HAX1,ATP5MC1,HNRNPL,PLG,PRNP,GPM6A |
| 7.646e-03 | -4.87 | RNF24 (ring finger protein 24) | protein interactions | 11237 | 17 | 10 | 19454 | 5460 |
ABHD5,VAMP1,NRSN1,TIMMDC1,ARMC1,TMX2,PLP1,MFSD14B,CNIH1,UQCRH |
| 7.646e-03 | -4.87 | PRR27 (proline rich 27) | protein interactions | 401137 | 17 | 10 | 19454 | 5460 |
NUDT12,PSMG2,PSMG3,IDE,TCAF2,TIMM10,SQSTM1,UBASH3B,HECTD3,PSMG4 |
| 7.646e-03 | -4.87 | SHROOM1 (shroom family member 1) | protein interactions | 134549 | 17 | 10 | 19454 | 5460 |
GARRE1,ATG16L1,BAG2,YWHAG,CLK1,XPO1,YWHAH,DYRK1A,YWHAB,SOCS2 |
| 7.646e-03 | -4.87 | BCAS4 (breast carcinoma amplified sequence 4) | protein interactions | 55653 | 17 | 10 | 19454 | 5460 |
BORCS5,ATG4A,SPPL3,BLOC1S5,BORCS7,ENKD1,DPY30,SNAPIN,BLOC1S3,BLOC1S2 |
| 7.646e-03 | -4.87 | C16orf92 (chromosome 16 open reading frame 92) | protein interactions | 146378 | 17 | 10 | 19454 | 5460 |
NSG1,CXCL9,NDFIP1,PLPP6,LRP10,SEC22A,BIRC2,TRAF2,RETREG3,PGA4 |
| 7.646e-03 | -4.87 | CHI3L1 (chitinase 3 like 1) | protein interactions | 1116 | 17 | 10 | 19454 | 5460 |
IDH3B,HSPA8,UBLCP1,CALR,PRSS23,CCR1,CHI3L1,ATP6AP2,RIGI,SPPL3 |
| 7.646e-03 | -4.87 | FAM53B (family with sequence similarity 53 member B) | protein interactions | 9679 | 17 | 10 | 19454 | 5460 |
SFN,ACTA2,YWHAH,XPO1,YWHAG,DYNLL1,YWHAZ,VIRMA,YWHAB,DYRK1A |
| 7.648e-03 | -4.87 | PRDM5 (PR/SET domain 5) | protein interactions | 11107 | 57 | 25 | 19454 | 5460 |
RPL26L1,RBM34,DDX39A,GFI1,KIF1C,BRIX1,CMAS,RASD1,RPL4,VIPR1,FBXO11,EEIG2,NGRN,RPL10A,CASC3,PRSS1,FTSJ3,FBXO44,RPF2,RPL7A,ZNF687,SURF6,TXN,RPL8,ZNF22 |
| 7.648e-03 | -4.87 | ST3GAL4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4) | protein interactions | 6484 | 57 | 25 | 19454 | 5460 |
NDUFA4,TMX3,TAS1R2,GPIHBP1,LCN9,SLC31A1,EDDM3B,CLSTN3,KLRD1,SCGB1C1,FAM3C,GGT7,OAF,APEX1,RMND1,FAM20C,LRFN3,CSGALNACT2,LCN6,BPNT2,MSMB,HFE,BTN2A2,C1GALT1C1,LRP6 |
| 7.648e-03 | -4.87 | TRAFD1 (TRAF-type zinc finger domain containing 1) | protein interactions | 10906 | 57 | 25 | 19454 | 5460 |
TES,LMBR1L,CCNF,EGLN3,FZR1,MARCHF4,FBXO22,XPO1,CUL3,ILK,UBE2H,FAS,TRAF6,IGF1R,HSPA5,HSCB,CDK20,ASPM,ISG15,CFTR,NAA15,B3GNT2,E2F4,VPS33A,KDELR1 |
| 7.648e-03 | -4.87 | CSRP1 (cysteine and glycine rich protein 1) | protein interactions | 1465 | 57 | 25 | 19454 | 5460 |
PGK1,HSPA8,TES,FOLR1,TRIP4,FUBP3,PML,CDK9,CSRP1,ESR2,UFM1,CFL1,HDAC6,MSX2,BAG3,B3GNT2,MYC,RAB11A,UBE2H,HSPB1,ASCC1,SPOP,EZH2,ACAA2,CHMP4C |
| 7.648e-03 | -4.87 | TMEM140 (transmembrane protein 140) | protein interactions | 55281 | 57 | 25 | 19454 | 5460 |
STOM,LMNA,TMEM182,CLRN1,STXBP1,TMEM205,APH1A,SIT1,NDUFB5,TMX2,SLC39A9,FCER1G,CGRRF1,PDZK1IP1,SCN3B,CREB3,KCNJ8,SYNE4,FNDC9,MGST3,VIRMA,MSMO1,TSPO2,SLC38A2,RMDN3 |
| 7.648e-03 | -4.87 | ZNF593 (zinc finger protein 593) | protein interactions | 51042 | 57 | 25 | 19454 | 5460 |
CHCHD2,UCHL3,MEPCE,PRDX4,POLR1H,RAB1A,FGF3,PICK1,PMAIP1,ARRDC3,EZH2,DDIT4L,ATG16L1,FZR1,CGAS,EGLN3,SRPK2,USP5,DNPH1,SURF6,ATP6V1A,MECP2,RC3H2,PPP3CA,MYC |
| 7.648e-03 | -4.87 | DCTPP1 (dCTP pyrophosphatase 1) | protein interactions | 79077 | 57 | 25 | 19454 | 5460 |
APEX1,GNPDA1,HERC4,UBE2H,NOA1,NIF3L1,CFAP161,NTAQ1,MYC,DCTPP1,XPNPEP1,DUSP26,FXR2,PSMA1,NEDD8,PDE12,HSCB,PCNA,BAP1,RPA3,RPA2,SDCBP,SPG21,TULP3,MAP1LC3B |
| 7.648e-03 | -4.87 | ENSA (endosulfine alpha) | protein interactions | 2029 | 57 | 25 | 19454 | 5460 |
MCM3,CHCHD4,PPP2CB,POP7,ENO2,ARPP19,TES,KCTD15,TPPP2,IREB2,CBX5,RPP25,UBB,ZBTB2,SRPK2,KBTBD4,B3GNT2,PPP2R1A,DNAJC2,PPME1,BAP1,HSPA8,RAP2A,PSEN1,DNAJC22 |
| 7.655e-03 | -4.87 | Lagging Strand Synthesis | REACTOME pathways | R-HSA-69186 | 20 | 12 | 10285 | 3229 |
PCNA,FEN1,RPA2,PRIM2,RFC4,POLD2,RFC5,POLD4,RFC2,RPA3,POLA2,RFC3 |
| 7.655e-03 | -4.87 | Inactivation of APC/C via direct inhibition of the APC/C complex | REACTOME pathways | R-HSA-141430 | 20 | 12 | 10285 | 3229 |
ANAPC4,ANAPC16,ANAPC2,CDC20,ANAPC15,CDC23,CDC16,UBE2D1,MAD2L1,ANAPC11,CDC26,BUB3 |
| 7.655e-03 | -4.87 | Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | REACTOME pathways | R-HSA-141405 | 20 | 12 | 10285 | 3229 |
UBE2D1,CDC16,CDC23,ANAPC15,CDC20,ANAPC2,BUB3,ANAPC16,CDC26,ANAPC11,MAD2L1,ANAPC4 |
| 7.663e-03 | -4.87 | HLTF (helicase like transcription factor) | protein interactions | 6596 | 131 | 50 | 19454 | 5460 |
RNF146,RPA2,LMNA,EEF1G,COIL,RPA3,RNF113A,ANAPC16,HSPA8,FBXW11,BRCA1,ZBTB38,SP1,COP1,DTL,PMPCA,CUL3,MYC,RFC5,SNRNP40,ESR2,UBE2V2,ZNF330,CCNF,H2BC1,AQP3,RAD23B,CERK,ZNF263,FEN1,MGARP,H2AX,RBCK1,S100A10,RFC2,UBE2A,SNIP1,EMC2,EWSR1,PCNA,HAPSTR1,H2AC4,PDCD1,POU5F1,FAM174A,SHPRH,CDC5L,CDK9,UBE2N,CBFB |
| 7.668e-03 | -4.87 | Peptide hormone metabolism | REACTOME pathways | R-HSA-2980736 | 91 | 40 | 10285 | 3229 |
GNB3,SPCS1,KLF4,EXOC5,SPCS3,GH1,STX1A,CGB8,CTSD,REN,UCN,SLC30A5,SLC30A7,SPCS2,VAMP2,GNG13,MME,ENPEP,LEP,INHA,CPE,LHB,CMA1,ATP6AP2,EXOC3,CLTRN,ERO1A,RAB27A,SEC11A,EXOC8,ACHE,PAX6,PCSK2,EXOC2,CTNNB1,GHRL,IGF1,DPP4,EXOC1,MIR24-1 |
| 7.675e-03 | -4.87 | mitochondrial respiratory chain complex III | cellular component | GO:0005750 | 12 | 8 | 19108 | 5553 |
CYC1,UQCRQ,UQCC3,UQCR11,BCS1L,UQCRC2,UQCRH,UQCRC1 |
| 7.675e-03 | -4.87 | TRAPPII protein complex | cellular component | GO:1990071 | 12 | 8 | 19108 | 5553 |
TRAPPC13,TRAPPC1,TRAPPC6B,TRAPPC2L,TRAPPC4,TRAPPC14,TRAPPC10,TRAPPC3 |
| 7.675e-03 | -4.87 | respiratory chain complex III | cellular component | GO:0045275 | 12 | 8 | 19108 | 5553 |
UQCRC1,BCS1L,UQCRH,UQCRC2,UQCC3,UQCR11,UQCRQ,CYC1 |
| 7.675e-03 | -4.87 | transcription export complex | cellular component | GO:0000346 | 12 | 8 | 19108 | 5553 |
CHTOP,DDX39B,THOC2,THOC1,ZC3H11A,THOC3,ALYREF,THOC6 |
| 7.684e-03 | -4.87 | Fatty acid elongation | KEGG pathways | hsa00062 | 25 | 15 | 7161 | 2463 |
ELOVL3,HADHA,HACD1,MECR,HACD3,ELOVL1,PPT1,ELOVL7,ACAA2,HACD2,ELOVL4,HACD4,TECR,HADH,ELOVL6 |
| 7.684e-03 | -4.87 | Fatty acid elongation | KEGG pathways | ko00062 | 25 | 15 | 7161 | 2463 |
HACD3,ELOVL1,ELOVL7,PPT1,HADHA,ELOVL3,MECR,HACD1,TECR,HACD4,ELOVL4,ELOVL6,HADH,ACAA2,HACD2 |
| 7.724e-03 | -4.86 | TPTE (transmembrane phosphatase with tensin homology) | protein interactions | 7179 | 128 | 49 | 19454 | 5460 |
CYC1,PIH1D1,VAPB,UBAC2,TRAM1,NTPCR,TOR1AIP2,UNC45A,EMC1,PHB2,ADRB2,MTDH,HADHA,EPHA2,SLC38A1,XPOT,VEZT,PPP5C,SEC63,RETREG3,SEC61A1,SURF4,RPN1,TFRC,BZW2,LGR4,ERLIN2,CCDC47,IPO8,PSMD12,SMN1,CSE1L,RPAP3,SLC39A7,STX18,TMED1,OSBPL8,XPO1,QPCTL,ILVBL,VCPKMT,DIPK2A,PTPN1,HACD3,NAP1L5,WDR6,PTK7,SRPRA,PHB1 |
| 7.724e-03 | -4.86 | UHRF2 (ubiquitin like with PHD and ring finger domains 2) | protein interactions | 115426 | 128 | 49 | 19454 | 5460 |
XRCC5,SKP1,MBD3,DESI1,FBXW7,HMGB1,UBE2D3,UBE2K,CDKN1A,CCNA2,CCND1,PGRMC1,UBE2W,LUC7L3,ZNF574,CDK1,UBE2I,TRIM27,LIG3,GMPS,NCAPG2,RUNX1,CUL3,CCNB1,CDC16,BAX,CDC73,PCNA,SSRP1,RBCK1,KRAS,H3C1,KDM4B,CDK4,TP53,CDK6,RB1,MCL1,EED,ACTA2,MPG,CTNNB1,TRIM8,BRD3,BCL2L1,KDM2A,POLB,UBE2D1,SMAD4 |
| 7.728e-03 | -4.86 | 4_helix_cytokine-like_core | interpro domains | IPR009079 | 55 | 25 | 18521 | 5414 |
IL2,IL6,GH1,IL15,IL23A,OSM,IL22,IFNK,IL13,IL3,IFNA13,IL4,IFNA10,EPO,IFNG,LEP,CSH1,IL10,IFNB1,IL5,IL21,IFNA2,CSF2,PRL,IL12A |
| 7.736e-03 | -4.86 | ATP7A (ATPase copper transporting alpha) | protein interactions | 538 | 86 | 35 | 19454 | 5460 |
ARL15,FURIN,RAB4A,TMEM59,HCST,MGARP,KLRD1,TACR3,STX7,CLU,KRAS,SEMA4C,CD83,RAB29,HNRNPD,LY6G5C,NCR3LG1,LAMTOR1,RHOB,LAMP3,DNAJC5,RAB2A,ATG9A,LAMP2,DPP4,RAB5C,DNAJB2,DIRAS3,ITM2A,GLRX,VIRMA,CX3CL1,GJA1,HRAS,RAB35 |
| 7.762e-03 | -4.86 | oxidoreductase complex | cellular component | GO:1990204 | 121 | 48 | 19108 | 5553 |
NDUFAB1,RRM1,GPD2,NDUFS3,SDHB,NDUFA4,CBR4,NDUFS2,DBT,NDUFS6,SDHC,NDUFS8,OGDHL,NDUFC2,KGD4,NDUFA1,NDUFB10,UQCC3,UQCR11,CYC1,PDHA1,NDUFV2,NDUFB4,RAC2,NDUFA5,LDHA,PDHB,BCS1L,NDUFB8,UQCRC2,NDUFB6,DLST,NDUFB5,CYB5B,UQCRC1,LDHAL6B,NDUFA2,UQCRH,NDUFB7,DLAT,LDHB,BCKDK,UQCRQ,HSD17B8,CYB5R3,IDH3B,NDUFA12,IDH3A |
| 7.780e-03 | -4.86 | NHP2 (NHP2 ribonucleoprotein) | protein interactions | 55651 | 125 | 48 | 19454 | 5460 |
TCOF1,ARGLU1,PTGES3,KRAS,SOX2,RAF1,NUPR1,MRPL49,CHMP4C,PHB1,SSBP1,ZBTB2,DKC1,SRSF10,PRNP,MRPL50,LYAR,CAND1,NOP58,XPO1,IFI16,NOL12,TERC,NOS1AP,MRPL18,UTP23,MRPL17,EIF5B,TRA2B,ATG16L1,PIH1D1,LMNA,WRAP53,UBE2I,DLST,RSRC1,ESR2,FBXO22,PPP1CC,BTF3,SUB1,RSPH1,MYC,RIT1,UBE2H,H1-1,RC3H2,ATG3 |
| 7.812e-03 | -4.85 | BCL10 (BCL10 immune signaling adaptor) | protein interactions | 8915 | 89 | 36 | 19454 | 5460 |
TNFAIP3,AKT1,DPP4,XPO1,BCL10,IKBKB,TRAF6,HTRA2,SLC20A1,AIP,SRSF1,UBE2N,NFKBIA,MAP1LC3A,CDK9,UBE2V2,PRKCQ,FBP1,PPP2R1A,TRAF2,SOCS3,VAPB,NHERF1,IL15RA,CARD19,CSNK1A1,RNF181,OTULIN,RNF8,TLR4,BIRC2,SQSTM1,CAMK2G,TRMO,RBCK1,ANP32B |
| 7.835e-03 | -4.85 | upper_aerodigestive_tract-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-carcinoma | 383 | 132 | 16828 | 4835 |
RB1,CTNNB1,TGFBR2,PTPN11,NEK9,PIK3CA,DMPK,MAP3K12,VRK1,CPT1B,GUK1,DDX1,TCEA1,STK38,RAF1,ZMYM2,SRPK2,CDK6,KIT,DAPK3,JAK2,CDK4,PIK3R2,SRP72,NEK7,DDIT3,NTRK3,CKB,AKT2,PSMC5,CERK,CDK7,NME1,DAPK1,STK3,STK38L,CSNK2A1,CCND3,WRAP53,FXN,PTK7,AKT1,DLG3,NEO1,COMMD3,PRKCA,CSNK1G3,NUP62,NUCKS1,JAK1,MAP2K1,STK24,WIF1,FN3KRP,STK11,TFG,TP53,MET,IP6K1,CDK8,CMPK1,THOC6,CINP,GSK3A,BTG1,AK2,GTF2F1,YES1,UCKL1,SEPHS2,CDK17,CDC7,CSNK1A1,PRKACB,DLG1,UHMK1,ACVR1B,RB1CC1,CSNK2B,PIP4K2C,MAP3K11,PIK3R3,SYK,AURKAIP1,DYRK2,PIK3CG,ATP1B1,MAP3K3,PRKAG1,SRC,ROCK2,IRAK4,DCK,RPS6KA4,BMPR1A,DTYMK,CKS1B,CSNK1E,DYRK1A,FGR,CDK5,NME4,PRKCB,AKT3,NTRK2,SEPHS1,PRKRA,TRIM27,PIK3R1,EIF2AK2,CLK1,MAP2K6,MAP2K3,PRPSAP1,LCP1,AGGF1,FBXW7,IGF1R,DDR1,ACVR1,CAMK2N1,FGFR1,CENPP,CASK,CDKN1A,ATF1,DUSP22,CAMK2G,TNIK,CCNH,GOLGA5,CRKL |
| 7.835e-03 | -4.85 | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | 383 | 132 | 16828 | 4835 |
PIK3CG,DYRK2,AURKAIP1,MAP3K11,PIK3R3,SYK,MAP3K3,IRAK4,ROCK2,SRC,PRKAG1,ATP1B1,CDC7,CDK17,SEPHS2,UCKL1,CSNK2B,RB1CC1,ACVR1B,PIP4K2C,CSNK1A1,UHMK1,DLG1,PRKACB,FGFR1,CAMK2N1,ACVR1,CENPP,CDKN1A,CASK,DDR1,IGF1R,AGGF1,LCP1,FBXW7,PRPSAP1,DUSP22,CRKL,GOLGA5,TNIK,CCNH,CAMK2G,ATF1,FGR,DYRK1A,CSNK1E,CDK5,DTYMK,CKS1B,BMPR1A,DCK,RPS6KA4,EIF2AK2,MAP2K3,MAP2K6,CLK1,SEPHS1,NTRK2,AKT3,PRKCB,NME4,PIK3R1,TRIM27,PRKRA,NEK7,DDIT3,CDK4,SRP72,PIK3R2,CERK,PSMC5,AKT2,CKB,NTRK3,DAPK3,KIT,JAK2,STK38L,STK3,DAPK1,CSNK2A1,CDK7,NME1,MAP3K12,DMPK,PIK3CA,VRK1,CTNNB1,RB1,NEK9,PTPN11,TGFBR2,STK38,TCEA1,CDK6,ZMYM2,SRPK2,RAF1,GUK1,CPT1B,DDX1,CDK8,CMPK1,THOC6,MET,TP53,TFG,IP6K1,BTG1,YES1,AK2,GTF2F1,GSK3A,CINP,NEO1,DLG3,CSNK1G3,PRKCA,COMMD3,WRAP53,CCND3,AKT1,PTK7,FXN,STK11,FN3KRP,WIF1,MAP2K1,STK24,NUCKS1,NUP62,JAK1 |
| 7.835e-03 | -4.85 | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | 383 | 132 | 16828 | 4835 |
PRKACB,DLG1,UHMK1,CSNK1A1,PIP4K2C,ACVR1B,RB1CC1,CSNK2B,SEPHS2,UCKL1,CDK17,CDC7,ATP1B1,PRKAG1,SRC,ROCK2,IRAK4,MAP3K3,SYK,MAP3K11,PIK3R3,AURKAIP1,DYRK2,PIK3CG,PRKRA,TRIM27,PIK3R1,NME4,PRKCB,AKT3,NTRK2,SEPHS1,CLK1,MAP2K6,MAP2K3,EIF2AK2,DCK,RPS6KA4,BMPR1A,DTYMK,CKS1B,CDK5,DYRK1A,CSNK1E,FGR,ATF1,CAMK2G,CCNH,GOLGA5,TNIK,CRKL,DUSP22,PRPSAP1,LCP1,FBXW7,AGGF1,IGF1R,DDR1,CDKN1A,CASK,CENPP,CAMK2N1,ACVR1,FGFR1,DDX1,CPT1B,GUK1,RAF1,ZMYM2,SRPK2,CDK6,TCEA1,STK38,TGFBR2,NEK9,PTPN11,RB1,CTNNB1,VRK1,PIK3CA,MAP3K12,DMPK,NME1,CDK7,CSNK2A1,DAPK1,STK3,STK38L,JAK2,KIT,DAPK3,NTRK3,AKT2,CKB,PSMC5,CERK,PIK3R2,CDK4,SRP72,DDIT3,NEK7,JAK1,NUP62,NUCKS1,STK24,MAP2K1,FN3KRP,WIF1,STK11,FXN,PTK7,AKT1,WRAP53,CCND3,COMMD3,PRKCA,CSNK1G3,DLG3,NEO1,GSK3A,CINP,GTF2F1,AK2,YES1,BTG1,IP6K1,TFG,TP53,MET,THOC6,CMPK1,CDK8 |
| 7.835e-03 | -4.85 | salivary_gland-carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma | 383 | 132 | 16828 | 4835 |
IP6K1,TP53,TFG,MET,CMPK1,THOC6,CDK8,GSK3A,CINP,GTF2F1,AK2,YES1,BTG1,FXN,AKT1,PTK7,WRAP53,CCND3,COMMD3,CSNK1G3,PRKCA,DLG3,NEO1,JAK1,NUCKS1,NUP62,WIF1,FN3KRP,MAP2K1,STK24,STK11,JAK2,DAPK3,KIT,AKT2,CKB,NTRK3,CERK,PSMC5,CDK4,PIK3R2,SRP72,DDIT3,NEK7,NME1,CDK7,CSNK2A1,STK3,DAPK1,STK38L,TGFBR2,NEK9,PTPN11,CTNNB1,RB1,VRK1,PIK3CA,MAP3K12,DMPK,DDX1,GUK1,CPT1B,ZMYM2,SRPK2,RAF1,CDK6,TCEA1,STK38,FBXW7,LCP1,AGGF1,PRPSAP1,DDR1,IGF1R,CENPP,CDKN1A,CASK,ACVR1,CAMK2N1,FGFR1,ATF1,CCNH,GOLGA5,TNIK,CAMK2G,CRKL,DUSP22,BMPR1A,RPS6KA4,DCK,DTYMK,CKS1B,CDK5,FGR,DYRK1A,CSNK1E,PRKRA,TRIM27,PIK3R1,PRKCB,NME4,NTRK2,SEPHS1,AKT3,MAP2K6,CLK1,MAP2K3,EIF2AK2,SYK,MAP3K11,PIK3R3,AURKAIP1,PIK3CG,DYRK2,ATP1B1,SRC,PRKAG1,IRAK4,ROCK2,MAP3K3,UCKL1,SEPHS2,CDK17,CDC7,PRKACB,UHMK1,DLG1,CSNK1A1,PIP4K2C,ACVR1B,CSNK2B,RB1CC1 |
| 7.835e-03 | -4.85 | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | 383 | 132 | 16828 | 4835 |
GOLGA5,CCNH,TNIK,CAMK2G,CRKL,DUSP22,ATF1,CASK,CENPP,CDKN1A,ACVR1,CAMK2N1,FGFR1,AGGF1,LCP1,FBXW7,PRPSAP1,DDR1,IGF1R,MAP2K6,CLK1,MAP2K3,EIF2AK2,PRKRA,TRIM27,PIK3R1,PRKCB,NME4,NTRK2,SEPHS1,AKT3,CDK5,FGR,DYRK1A,CSNK1E,BMPR1A,DCK,RPS6KA4,DTYMK,CKS1B,SRC,PRKAG1,IRAK4,ROCK2,MAP3K3,ATP1B1,AURKAIP1,DYRK2,PIK3CG,SYK,PIK3R3,MAP3K11,PIP4K2C,ACVR1B,CSNK2B,RB1CC1,PRKACB,UHMK1,DLG1,CSNK1A1,CDC7,SEPHS2,UCKL1,CDK17,AK2,GTF2F1,YES1,BTG1,GSK3A,CINP,THOC6,CMPK1,CDK8,IP6K1,TP53,TFG,MET,FN3KRP,WIF1,MAP2K1,STK24,STK11,JAK1,NUCKS1,NUP62,COMMD3,CSNK1G3,PRKCA,DLG3,NEO1,FXN,AKT1,PTK7,WRAP53,CCND3,CSNK2A1,STK3,DAPK1,STK38L,NME1,CDK7,AKT2,CKB,NTRK3,PSMC5,CERK,PIK3R2,CDK4,SRP72,DDIT3,NEK7,JAK2,DAPK3,KIT,ZMYM2,SRPK2,RAF1,CDK6,STK38,TCEA1,DDX1,GUK1,CPT1B,VRK1,PIK3CA,DMPK,MAP3K12,TGFBR2,PTPN11,NEK9,CTNNB1,RB1 |
| 7.850e-03 | -4.85 | ATPase binding | molecular function | GO:0051117 | 84 | 36 | 18094 | 5411 |
ATP1B3,GABARAPL2,ATP1B1,VCPKMT,DNAJC10,SDF2L1,SNX10,PLN,ZNHIT6,AR,TAF9,TRPC1,SELENOS,NOP58,SYVN1,NCSTN,PIH1D1,SNTA1,RALB,SRC,CAV1,ATP6V1G1,RUVBL2,PPP3CA,RUVBL1,NR1H2,TOR1AIP2,PSEN1,SVIP,PGR,METTL21A,RALA,TMEM106B,PEX26,ATP5IF1,DERL1 |
| 7.850e-03 | -4.85 | Calnexin/calreticulin cycle | REACTOME pathways | R-HSA-901042 | 27 | 15 | 10285 | 3229 |
SYVN1,EDEM3,UBB,EDEM2,UBA52,RPS27A,GANAB,RNF103,RNF5,DERL2,PDIA3,CALR,OS9,RNF139,EDEM1 |
| 7.853e-03 | -4.85 | MBIP (MAP3K12 binding inhibitory protein 1) | protein interactions | 51562 | 165 | 61 | 19454 | 5460 |
PSME1,MYD88,EWSR1,RUVBL2,TRIM63,RERE,COPS4,STX11,POLE4,VTA1,WDR37,IKZF5,PPP2R1A,CDK8,PSMC3,CIBAR1,SMARCB1,KLHL26,FAM199X,MIF,PLEKHF2,CRTAP,TAF9,HCFC2,DR1,HSPB2,DGCR6L,FXR2,SGF29,VPS28,CXXC1,ING5,KLF12,LMO3,SUPT3H,MAP3K12,MED23,P3H1,PPARG,KLF3,SUPT7L,PHF21A,POLR3H,RPL37A,ACTB,APEX1,MAD2L1,PIK3R3,MYC,TAF5L,LMO2,PCBD1,BRMS1,CCDC85B,KANSL3,RNF40,TADA3,LMNB1,TADA1,EXOC8,OSGEP |
| 7.853e-03 | -4.85 | C8orf33 (chromosome 8 open reading frame 33) | protein interactions | 65265 | 165 | 61 | 19454 | 5460 |
RNF113A,UFL1,RPL4,ZC3H15,SYK,CPSF4,CFTR,LAMP5,ZNF574,NOL7,RPL26L1,RPLP0,LMBR1L,PNMA1,CCNF,ENO1,RBMX2,PRKRA,MRPS28,FBXO22,SRPK2,MYC,RPL7A,EPS8,CUL3,ZNF668,CEP70,TRIM23,RC3H2,UBE2H,RPL23A,RPL3,BLOC1S2,MRFAP1,PICK1,MEPCE,RAF1,MAGEB10,TUBA1A,NFE2L1,LLPH,DISC1,ZNF526,AAMP,RPL8,MRPS9,FEZ1,PHB1,CAND1,LYAR,DKC1,SURF6,MRPS23,IFI16,MOV10,MDFI,KRBOX4,COPS5,DDRGK1,SNRNP70,RPL10A |
| 7.856e-03 | -4.85 | positive regulation of NF-kappaB transcription factor activity | biological process | GO:0051092 | 137 | 54 | 18204 | 5365 |
TRIM34,TRIM37,CLU,UBE2V1,PSMA6,IL18,DHX9,BCL10,CD40,RPS6KA4,IL1B,SLCO3A1,S100A8,TNFSF18,PYCARD,AGER,MTDH,TRIM21,IL1RAP,CD40LG,TLR4,TRIM5,DDRGK1,TNF,TRIM68,TRAF1,TRIM32,TRAF2,CLEC7A,IL6,TRIM62,PPIA,EDA2R,TRIM6,RPS3,TRIM8,PRDX3,TFRC,TRIM22,TLR9,TRIM52,MYD88,TRAF6,NLRP3,EIF2AK2,PRKCQ,TLR2,AR,UBE2N,IKBKB,RBCK1,MTPN,TIRAP,TRIM15 |
| 7.856e-03 | -4.85 | myeloid leukocyte migration | biological process | GO:0097529 | 137 | 54 | 18204 | 5365 |
IL6,CCL24,PPIA,CXCL11,JAGN1,SELENOK,PAFAH1B1,DPEP1,CXCL9,CCL5,CXCL8,TGFB2,CX3CL1,XCL1,FCER1G,CCL11,S100A8,CCR7,CCL8,FOLR2,CXCL1,PDE4B,PIK3CG,MSMP,SYK,CCL3,SCG2,CXCR1,PPIB,CCL23,IL1B,CCL18,CHGA,CCL4L1,LGALS3,CXCL10,SRP54,CCL2,B4GALT1,CXCL13,JAML,SFTPD,CCL19,CCR2,CXCL3,ADGRE2,RPL13A,PIK3R1,EMP2,CKLF,CCL25,KIT,IRAK4,CCL1 |
| 7.872e-03 | -4.84 | ZNF207 (zinc finger protein 207) | protein interactions | 7756 | 92 | 37 | 19454 | 5460 |
NUPR1,RPA2,EZH2,IDH2,RAF1,WDR77,ZC3H14,TP53,MDC1,RIGI,EIF5B,KRAS,STAU1,HSPA8,ABCE1,EWSR1,RPA3,SNRPA,PML,HNRNPD,UBE2H,POLR1B,BRCA1,BTF3,ZNF207,DDRGK1,MOV10,PDIA3,MYC,DPY30,SNRPB2,NUP35,FZR1,BUB3,PRNP,SNRNP40,UBE2N |
| 7.872e-03 | -4.84 | APOA2 (apolipoprotein A2) | protein interactions | 336 | 92 | 37 | 19454 | 5460 |
ESR2,TAB1,MED17,FBXO22,CYBC1,GNPAT,ALB,SSMEM1,MED4,PDZK1IP1,AGPAT1,MED10,MED21,MED27,SCGB1D1,ELMOD2,CREB3,RNF11,HSPA5,SLC7A1,MED11,EMC8,EMC1,PCYOX1L,CHST10,CCR1,APOC2,MED31,TMEM39A,QRSL1,LMNA,STOM,MED30,JUN,TMEM45A,GDE1,MED9 |
| 7.872e-03 | -4.84 | IRS2 (insulin receptor substrate 2) | protein interactions | 8660 | 92 | 37 | 19454 | 5460 |
PIK3CA,RPA2,NETO2,TOP3B,SOCS3,PIK3R2,KDM1A,DVL2,IGF1R,MTDH,JAK1,SHC1,YWHAZ,FBXW11,RHOB,YWHAB,BCL2L1,USP15,PTPN11,GRB10,SFN,CUL3,PIK3R3,MYC,PIK3R1,YWHAG,XPO1,YWHAH,FBXO22,SPPL3,JAK2,VIRMA,SRPK2,EGLN3,COPS2,PHF21A,AP2M1 |
| 7.872e-03 | -4.84 | POTEI (POTE ankyrin domain family member I) | protein interactions | 653269 | 92 | 37 | 19454 | 5460 |
AASDHPPT,ACTB,TMOD3,C1QTNF1,PLEKHF1,MALSU1,MARCHF9,CYTH1,SYNGR1,TEX19,LRRC20,CCDC22,MYO6,HTRA2,NUS1,RRN3,CAP2,TMED5,USP14,DDRGK1,HSD17B3,ARL6IP6,DKK1,TRIM37,PCGF3,EIF1B,MEPCE,SLC25A11,MAEA,MME,TEX264,EMP3,LPAR2,OSER1,SMNDC1,TFCP2,HEXIM1 |
| 7.872e-03 | -4.84 | GFER (growth factor, augmenter of liver regeneration) | protein interactions | 2671 | 92 | 37 | 19454 | 5460 |
PPWD1,MARS1,KRAS,KDM1A,HSCB,TTC4,CMC4,S100B,SFXN1,FAM136A,TUBB4B,HOXB1,TIMM8A,TIMM10,CDK4,EGLN3,ROMO1,TXN,PLEKHF2,PGPEP1,TUBB,POLR3B,CALML5,COPS2,CCNF,AIFM1,S100A6,COX4I1,SMAD2,RIT1,ZCCHC9,CHCHD4,ATG7,COPS5,NTAQ1,KLHL22,CUL3 |
| 7.875e-03 | -4.84 | DCAF10 (DDB1 and CUL4 associated factor 10) | protein interactions | 79269 | 119 | 46 | 19454 | 5460 |
ADRB2,PRRG1,PPP2R2C,SNX11,TMEM160,PRIM2,CORO6,RNF113A,SPATA2L,SPRYD4,RTF2,ACACA,CCND1,RPS14,FBXL19,AGO1,TXNDC12,PRDX2,SRPK2,MYG1,SRXN1,CCNF,SLA2,RPS3,ZMAT5,PLCL1,CCT2,COPS7A,PCCB,BACH1,TCEA2,ARGLU1,BAG2,JRKL,TPPP,STK16,MSRB3,GNAZ,TP53,TCP1,CCT7,DIRAS3,NKIRAS2,EGLN3,FABP5,HSPB8 |
| 7.875e-03 | -4.84 | ANKRD26 (ankyrin repeat domain containing 26) | protein interactions | 22852 | 119 | 46 | 19454 | 5460 |
NDC80,DPP4,CTNNB1,YWHAH,YWHAG,RHOG,YWHAB,RB1CC1,MED4,RAB35,KRT8,CORO1C,GJA1,MIF,RHOH,CAV1,DIRAS3,STX6,SOX2,RND3,NTRK2,SLC2A8,KRAS,FLOT1,SFN,RAB11A,DNAJC5,RHOB,BRCA1,YWHAZ,MAPRE1,NRP1,CTNNA1,LURAP1,ANAPC2,RHOJ,VIRMA,H1-5,RND2,CDC42,FGFR1,RHOU,RAB9A,STAU1,WDR3,STX7 |
| 7.875e-03 | -4.84 | MCM10 (minichromosome maintenance 10 replication initiation factor) | protein interactions | 55388 | 119 | 46 | 19454 | 5460 |
DPPA2,PRNP,EIF2B5,CDC5L,RAB35,ARL10,CDK6,MAP4,MICB,EMC8,TRIM37,MCM6,RPL31,PICK1,PNMA2,DISC1,RELL2,POLR2G,SUPT5H,IKZF5,RPL15,DAPK1,VIRMA,TNFRSF1B,CDC7,TMEM74,RHOB,BRCA1,MYC,ANAPC15,CAV3,MCM3,CEP70,MCM4,CCDC85B,SLC31A1,MCMBP,TRIM52,FTL,CCND3,TEX264,PML,CCND1,EHHADH,FAXC,CDKN1A |
| 7.888e-03 | -4.84 | intracellular protein transmembrane transport | biological process | GO:0065002 | 31 | 16 | 18204 | 5365 |
SRP54,HSPA5,PEX26,SEC62,TRAM1,SEC61A1,TRIM37,SEC61B,TRAM1L1,PEX13,TRAM2,SEC61G,PEX5L,SEC61A2,ZFAND2B,SEC63 |
| 7.888e-03 | -4.84 | viral protein processing | biological process | GO:0019082 | 31 | 16 | 18204 | 5365 |
ST3GAL4,GSK3A,EDEM2,FUT8,SPCS1,CSNK1A1,MGAT1,ST3GAL1,MGAT4B,MGAT4A,ST3GAL2,FURIN,ST6GAL1,GALNT1,SPCS3,ST6GALNAC3 |
| 7.888e-03 | -4.84 | dopamine receptor signaling pathway | biological process | GO:0007212 | 31 | 16 | 18204 | 5365 |
GNA11,GNAO1,DRD3,GNAQ,DRD1,GNA14,GSK3A,NCSTN,SLC1A1,PTGER1,GNG2,NSG1,CALY,GNAI3,GNB1,NHERF1 |
| 7.898e-03 | -4.84 | PDE6B (phosphodiesterase 6B) | protein interactions | 5158 | 8 | 6 | 19454 | 5460 |
PPP1CC,FEM1B,PYGB,PIWIL1,MUL1,CTBP1 |
| 7.898e-03 | -4.84 | HMGB3P1 (high mobility group box 3 pseudogene 1) | protein interactions | 128872 | 8 | 6 | 19454 | 5460 |
COPS5,CUL3,UQCRH,CAND1,CHMP4C,AGR2 |
| 7.898e-03 | -4.84 | RPSAP15 (ribosomal protein SA pseudogene 15) | protein interactions | 220885 | 8 | 6 | 19454 | 5460 |
CRBN,CAND1,CUL3,SMAD3,EWSR1,COPS5 |
| 7.898e-03 | -4.84 | MINAR1 (membrane integral NOTCH2 associated receptor 1) | protein interactions | 23251 | 8 | 6 | 19454 | 5460 |
SEC22A,PDCD10,SEC23A,VIRMA,CINP,TRAF3IP3 |
| 7.898e-03 | -4.84 | TREML1 (triggering receptor expressed on myeloid cells like 1) | protein interactions | 340205 | 8 | 6 | 19454 | 5460 |
TREML1,ATP1A3,PTPN11,PRSS8,RIGI,TMBIM6 |
| 7.898e-03 | -4.84 | CCDC30 (coiled-coil domain containing 30) | protein interactions | 728621 | 8 | 6 | 19454 | 5460 |
RIGI,BRAP,DDX39A,ARL10,INSIG2,CSK |
| 7.898e-03 | -4.84 | Rasd2 (RASD family, member 2) | protein interactions | 75141 | 8 | 6 | 19454 | 5460 |
SMAD2,SMURF1,ACVR1,BMPR1B,SMAD4,SMAD3 |
| 7.898e-03 | -4.84 | Rps27a (ribosomal protein S27A) | protein interactions | 78294 | 8 | 6 | 19454 | 5460 |
SMAD4,YWHAZ,ACVR1,SMAD2,SMURF1,BMPR1B |
| 7.898e-03 | -4.84 | CATSPERE (catsper channel auxiliary subunit epsilon) | protein interactions | 257044 | 8 | 6 | 19454 | 5460 |
OGDHL,PYGB,SPPL3,FKBP14,GNPTG,ACTA2 |
| 7.898e-03 | -4.84 | HECTD2 (HECT domain E3 ubiquitin protein ligase 2) | protein interactions | 143279 | 8 | 6 | 19454 | 5460 |
ACKR3,CALR,PIAS1,HSPA8,UBE2L3,BTG3 |
| 7.898e-03 | -4.84 | TOM20 (Tom20p) | protein interactions | 852973 | 8 | 6 | 19454 | 5460 |
NDC80,SERTAD1,CEP70,CSNK1A1,SGTA,CSNK2A1 |
| 7.898e-03 | -4.84 | STXBP5L (syntaxin binding protein 5L) | protein interactions | 9515 | 8 | 6 | 19454 | 5460 |
HNRNPL,STX12,ZDHHC15,CSK,GPSM3,SYVN1 |
| 7.898e-03 | -4.84 | ZNF140 (zinc finger protein 140) | protein interactions | 7699 | 8 | 6 | 19454 | 5460 |
CAND1,SRPK2,ARMC7,WDR83,CUL3,CEP70 |
| 7.898e-03 | -4.84 | SPPL2A (signal peptide peptidase like 2A) | protein interactions | 84888 | 8 | 6 | 19454 | 5460 |
DDX39A,VIRMA,SGTA,CCNF,NFKB1,LGALS8 |
| 7.898e-03 | -4.84 | ANKRD33B (ankyrin repeat domain 33B) | protein interactions | 651746 | 8 | 6 | 19454 | 5460 |
PPP3R2,HPCA,NCALD,TOP3B,VIRMA,SPPL3 |
| 7.898e-03 | -4.84 | Lsm3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 67678 | 8 | 6 | 19454 | 5460 |
LSM6,LSM5,SNRPE,SNRPG,TFIP11,EXOSC1 |
| 7.898e-03 | -4.84 | SEC16B (SEC16 homolog B, endoplasmic reticulum export factor) | protein interactions | 89866 | 8 | 6 | 19454 | 5460 |
FBXO7,HAPSTR1,SEC13,RAF1,SRPK2,SLC25A31 |
| 7.898e-03 | -4.84 | ZNF568 (zinc finger protein 568) | protein interactions | 374900 | 8 | 6 | 19454 | 5460 |
DDX39A,CBX5,PTP4A3,ILK,APEX1,CBX3 |
| 7.898e-03 | -4.84 | CPTP (ceramide-1-phosphate transfer protein) | protein interactions | 80772 | 8 | 6 | 19454 | 5460 |
ELOC,PHF13,ZNF451,SMAD3,TOP3B,INPP5K |
| 7.898e-03 | -4.84 | TOMM40L (translocase of outer mitochondrial membrane 40 like) | protein interactions | 84134 | 8 | 6 | 19454 | 5460 |
RAB1B,MOV10,TOMM22,ENO1,TOMM7,TOMM6 |
| 7.904e-03 | -4.84 | RESF1 (retroelement silencing factor 1) | protein interactions | 55196 | 35 | 17 | 19454 | 5460 |
TP53,EGR2,YWHAH,GABARAPL1,EXOC1,GABARAPL2,RPA2,ZDHHC15,TBC1D4,S100B,RPA3,ZMYM2,MAP1LC3A,PHF21A,KDM1A,MDM2,GABARAP |
| 7.904e-03 | -4.84 | MGST2 (microsomal glutathione S-transferase 2) | protein interactions | 4258 | 35 | 17 | 19454 | 5460 |
RELL2,CBL,PLN,MGST2,RAF1,CREB3,TP53,E2F4,SEC22B,DDX39A,SEC22A,CTXN3,ASIC1,TMEM167B,DNAJC30,VAMP3,STX8 |
| 7.904e-03 | -4.84 | FKRP (fukutin related protein) | protein interactions | 79147 | 35 | 17 | 19454 | 5460 |
CCL3,TMEM59,CSGALNACT2,SEC62,B3GNT2,KDSR,FAM234A,STAT6,LHFPL4,SLC39A9,LMBR1L,B4GAT1,SYNE4,CD1B,GPM6A,SLC7A14,SLC7A1 |
| 7.904e-03 | -4.84 | BLTP2 (bridge-like lipid transfer protein family member 2) | protein interactions | 9703 | 35 | 17 | 19454 | 5460 |
CIB2,STUB1,BAG2,RAB5A,HSPA8,ACTB,RIGI,VIRMA,DNAJB2,PSMC4,MLF1,TOP3B,COMMD5,HSPB8,RNF126,DNAJC7,BORCS8 |
| 7.904e-03 | -4.84 | PDCD1LG2 (programmed cell death 1 ligand 2) | protein interactions | 80380 | 35 | 17 | 19454 | 5460 |
SLC38A1,NCR3LG1,RAB4A,PDCD1,MFSD6,SLC38A7,FUT8,TMEM97,ALCAM,SLC7A1,GPR37L1,LGALS3,TMEM147,RUSF1,RAB35,ITM2B,LRP10 |
| 7.904e-03 | -4.84 | Hnrnpa3 (heterogeneous nuclear ribonucleoprotein A3) | protein interactions | 229279 | 35 | 17 | 19454 | 5460 |
HNRNPA2B1,FAM50B,CCNF,IMPACT,PTEN,DHX9,MATR3,HNRNPA0,HNRNPDL,HNRNPAB,HNRNPC,ELOC,HNRNPA1,ACAA2,STN1,ZNF326,HNRNPH3 |
| 7.904e-03 | -4.84 | SYNJ2 (synaptojanin 2) | protein interactions | 8871 | 35 | 17 | 19454 | 5460 |
YWHAB,MAPRE1,NCK1,BICD2,RPA2,YWHAG,YWHAH,H2BC9,SFN,SYNJ2BP,RIGI,VIRMA,STAU1,HNRNPL,SQSTM1,ANAPC2,RPA3 |
| 7.906e-03 | -4.84 | cadherin binding | molecular function | GO:0045296 | 335 | 121 | 18094 | 5411 |
SNX1,RPS26,LASP1,HSP90AB1,CTTN,RUVBL1,PPFIBP1,STX5,PTPN11,EHD1,VAPB,H3C1,EEF1G,EPCAM,EXOC3,RAN,USP8,PPME1,CBL,STK24,SH3GLB1,OLA1,SFN,UBFD1,LDHA,MYO1B,ZC3H15,PAK2,ARHGAP1,F11R,RPS2,GLOD4,CAPG,EFHD2,MAPRE1,ITGA6,PICALM,PSEN1,RPL23A,TAGLN2,CDH11,EHD4,PSMB6,ACVR1,TMPO,S100A11,PRDX6,CTNNB1,CCT8,TMOD3,SPTAN1,CHMP2B,CDH13,ARGLU1,IDH1,PAK6,RPL24,STK38,EEF2,CRKL,BZW2,CCS,MB21D2,YKT6,EIF4H,RPL15,CDH8,PTPN1,RAB11B,PRDX1,EIF3E,TES,ENO1,CD2AP,LYPLA2,CD46,YWHAZ,SRC,RTN4,SWAP70,RANBP1,NEO1,STXBP6,KLC2,CHMP5,STAT1,CTNNA2,AHSA1,RPL29,SEPTIN7,RAB1A,SNX5,RPL6,RPL7A,RARS1,CDH7,UNC45A,CDK5R1,YWHAB,HNRNPK,SH3GLB2,PKP4,CTNND1,HSPA8,BAG3,NIBAN2,CNN3,DLG1,H1-10,PROM1,JUP,ADD1,CAPZA1,SNX2,TRIM29,HSPA5,CTNNA1,SPTBN1,BMPR2,EPHA2,NCK1 |
| 7.913e-03 | -4.84 | UBQ-conjugat_E2 | interpro domains | IPR000608 | 39 | 19 | 18521 | 5414 |
UBE2N,UBE2G2,UBE2F,UBE2A,UBE2K,UBE2D3,UBE2S,UBE2V2,UBE2D1,UBE2M,UBE2L3,UBE2I,UBE2E3,UBE2H,KRAS,UBE2V1,UBE2W,UBE2B,UBE2E2 |
| 7.918e-03 | -4.84 | DDX3Y (DEAD-box helicase 3 Y-linked) | protein interactions | 8653 | 95 | 38 | 19454 | 5460 |
RAF1,MTF1,CFTR,EZH2,MIR20A,CHMP4C,PICALM,METTL14,EIF4B,HEXIM1,MIR7-1,TIMP3,RNF34,ZC3H11A,RNF10,HSCB,MEPCE,MIR106A,MIR107,TSPO,CEP15,STK38L,MIR143,MIR98,CD81,MIR31,SMAD2,FAM107A,MIR363,MIR34A,MIR106B,SMAD3,MIR7-2,CLDN3,MIRLET7B,MIR25,MIRLET7G,MIRLET7D |
| 7.918e-03 | -4.84 | SCN4A (sodium voltage-gated channel alpha subunit 4) | protein interactions | 6329 | 95 | 38 | 19454 | 5460 |
SELENOS,EMC4,SNTA1,CHST11,RPL10A,FITM2,H1-1,PTPN1,SELENOT,MFSD5,FZD6,GJA1,GPR89A,DNAJC1,TCP1,SLMAP,H1-5,MACO1,TMEM219,FAM162A,DLG3,SEC62,CYB5R1,SLC29A1,YIPF3,GLRB,DIPK1A,ST7,NHERF1,PIGW,GPAA1,DNAJC3,DLG1,TSPAN15,SYVN1,MYORG,B4GALT7,DNAJC30 |
| 7.918e-03 | -4.84 | ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2) | protein interactions | 954 | 95 | 38 | 19454 | 5460 |
EIF2B5,ASIC1,EIF2B2,DNAJB9,CD1A,EXTL2,PTPN1,CREB1,GLT8D1,ELSPBP1,SDF2L1,ATP1A3,HFE,SEC61A2,NCAPG2,FAM20B,RHEB,CD1B,CERS6,RAB18,DAD1,STX7,GPAA1,TMEM87A,TEX264,RAB13,GOLGA5,SFTPC,GHITM,EIF2B3,STIM1,OGFOD3,TOP3B,B3GALT4,PREB,B3GNT2,DCAKD,TMEM106A |
| 7.918e-03 | -4.84 | COASY (Coenzyme A synthase) | protein interactions | 80347 | 95 | 38 | 19454 | 5460 |
EMC1,G3BP1,KRAS,SAP18,RPL28,RIGI,RPA3,LGI1,AMACR,DCTN3,RPA2,PPME1,PIH1D1,SYK,DUSP14,CENPM,RFXANK,CFTR,LGALS3,CNTROB,MAD2L2,CLIC4,ACAP2,SRC,CCNF,CIB2,EFHD2,ENO2,EEF1AKMT3,KIAA1958,FAHD1,RHOB,RIT1,UBXN6,PTPN11,GFUS,GMPS,BAG3 |
| 7.925e-03 | -4.84 | negative regulation of signaling receptor activity | biological process | GO:2000272 | 26 | 14 | 18204 | 5365 |
RAMP3,SOCS4,CRHBP,PPARG,CNRIP1,PPARA,LILRB4,TNF,CLEC12B,TSG101,SOCS5,HFE,ERRFI1,CBL |
| 7.934e-03 | -4.84 | Protein processing in endoplasmic reticulum | KEGG pathways | hsa04141 | 165 | 72 | 7161 | 2463 |
BAK1,PLAA,HSP90B1,CAPN2,SKP1,SEC62,DDIT3,ERO1A,PDIA6,UBE2D3,STT3A,ERP29,MAN1A2,SELENOS,UBE2G2,RNF5,RPN1,EDEM1,STUB1,TRAM1,HSP90AA1,DNAJB2,CAPN1,NFE2L2,BAG2,UBE2D1,HSP90AB1,EDEM3,SEC13,SEC61A1,SEC23A,OS9,GANAB,XBP1,ATF4,SEC61G,RAD23B,EIF2AK2,SSR3,SYVN1,EIF2S1,NSFL1C,TUSC3,CASP12,SAR1B,CRYAB,HSPA8,PREB,HSPA5,BAX,DNAJC5,DNAJC1,ERLEC1,UFD1,SEC61A2,PDIA3,SSR1,DNAJC3,EDEM2,DAD1,LMAN1,DNAJC10,SSR2,DERL1,SVIP,SEC61B,SEC63,TRAF2,MAPK10,UBXN6,CALR,DERL2 |
| 7.934e-03 | -4.84 | Protein processing in endoplasmic reticulum | KEGG pathways | ko04141 | 165 | 72 | 7161 | 2463 |
DNAJC5,HSPA5,BAX,PREB,HSPA8,UFD1,ERLEC1,DNAJC1,EIF2S1,SYVN1,CRYAB,CASP12,SAR1B,TUSC3,NSFL1C,TRAF2,MAPK10,SEC63,DERL2,CALR,UBXN6,DAD1,EDEM2,DNAJC3,SSR1,PDIA3,SEC61A2,SEC61B,DERL1,SVIP,SSR2,LMAN1,DNAJC10,RPN1,SELENOS,UBE2G2,RNF5,MAN1A2,ERP29,DNAJB2,TRAM1,HSP90AA1,EDEM1,STUB1,ERO1A,SEC62,DDIT3,SKP1,PLAA,HSP90B1,BAK1,CAPN2,STT3A,UBE2D3,PDIA6,ATF4,SEC61G,GANAB,XBP1,SEC61A1,SEC23A,OS9,SSR3,RAD23B,EIF2AK2,CAPN1,SEC13,HSP90AB1,EDEM3,BAG2,NFE2L2,UBE2D1 |
| 7.941e-03 | -4.84 | WDR43 (WD repeat domain 43) | protein interactions | 23160 | 113 | 44 | 19454 | 5460 |
STAU1,FGF12,UFL1,KRAS,NPM3,H1-6,AATF,SIRT7,RPA3,RPL31,NUP50,RPS24,C1D,HAPSTR1,EXOSC3,EZH2,RPA2,NFKBIL1,CBX3,RHOBTB1,CERK,NUPR1,NOL7,UTP15,ING5,RAF1,SNRNP40,ESR2,APEX1,MAD2L1,ZNF330,CCNF,FGFBP1,CHCHD1,ATG3,DDX23,RIT1,MPHOSPH6,CIAO1,GRSF1,IFI16,MYC,DDRGK1,XPO1 |
| 7.941e-03 | -4.84 | RBM6 (RNA binding motif protein 6) | protein interactions | 10180 | 113 | 44 | 19454 | 5460 |
DDX5,NUP50,ACER3,SIRT7,SNRPA,EEF1G,PPP1CB,MFAP1,LSM2,FEM1A,PAK5,LMNA,ERH,ESR2,MIRLET7D,SPCS1,SNRNP40,MATR3,MYC,TXNIP,FTSJ3,BRCA1,EMC2,RIGI,THRAP3,CTNNBL1,TMEM45A,KIAA0408,JUN,DISC1,DDX42,FUBP3,CDC5L,NUP35,TOP1,MAPRE2,MITF,MIRLET7G,THOC1,HNRNPL,HNRNPA1,TAF7,PRPF19,DDX23 |
| 7.941e-03 | -4.84 | TOPBP1 (DNA topoisomerase II binding protein 1) | protein interactions | 11073 | 113 | 44 | 19454 | 5460 |
ZBTB17,APEX1,VIRMA,OTUD6A,PRPF18,EGLN3,ZNF330,ACAT1,MCPH1,BRCA1,RBBP8,RMI1,RIT1,TOPBP1,PDCD4,CDO1,NFYA,USP13,AKT1,SUV39H1,PPP1CC,SMC4,KRAS,HSPA5,PTGES3,MSH6,MDC1,NBN,PML,NLE1,TOP2B,RPA3,FHL3,HSPA8,BMPR2,CDK8,CBX3,RPA2,DTD1,TBC1D4,RAD1,TP53,CBLN4,RPAP2 |
| 7.941e-03 | -4.84 | NGDN (neuroguidin) | protein interactions | 25983 | 113 | 44 | 19454 | 5460 |
RPL13A,RPL19,SRPK2,ESR2,RPS3,FGFBP1,CSNK2B,RPS9,FBXW11,H1-1,MYC,RPL7A,DGCR8,HMGB1,RPL4,STAU1,AATF,RPA3,NMRAL1,RPA2,APOBEC3C,ZNF574,MFAP1,RPLP0,RPS14,FGF13,RPS10,ZBTB2,SRP14,KRR1,SRSF1,BECN1,RPS2,IFI16,H1-6,RPL17,RPL31,SNIP1,SLC16A1,RPL3,RPS24,RAF1,RPSA,H1-3 |
| 7.941e-03 | -4.84 | RANBP10 (RAN binding protein 10) | protein interactions | 57610 | 113 | 44 | 19454 | 5460 |
EGLN3,LILRB4,MRPL18,TCEAL9,IL17F,FGR,ARMC8,DDX50,SPON1,PSMA2,LECT2,MAEA,MKLN1,NDUFS6,ADAMTS1,NME1,HBP1,TOP3B,RAF1,LY6H,JPH4,DRD1,EMILIN3,SOX2,TULP3,BMP1,RAN,SYT2,YPEL5,UBE2H,HTRA2,CSK,CUL3,MRM2,UFL1,LARGE1,DVL2,GID4,GID8,RAB5A,CCDC106,RMND5B,MET,EIF4B |
| 7.949e-03 | -4.83 | ERK1 and ERK2 cascade | biological process | GO:0070371 | 52 | 24 | 18204 | 5365 |
PTGER4,SMAD4,GRB10,TLR4,CCL11,BTN2A2,SPRY1,YWHAZ,CDK1,SOX9,ITGAV,CD2AP,DUSP9,TBC1D10C,TF,OXTR,MYC,FGF10,FLCN,MAP2K1,FGF23,KARS1,INPPL1,DUSP6 |
| 7.949e-03 | -4.83 | negative regulation of epithelial to mesenchymal transition | biological process | GO:0010719 | 52 | 24 | 18204 | 5365 |
MAD2L2,SPRED1,PTEN,MIR204,TGFB2,MIR573,EPHA4,MIR144,MIR379,SFRP1,VEGFA,MIR145,MIR302B,SPRED2,TRIM62,MIR142,LDLRAD4,MIR149,SPRY1,MIR590,MIR130A,NOG,ADIPOR1,SDHAF2 |
| 7.949e-03 | -4.83 | cerebellar cortex development | biological process | GO:0021695 | 52 | 24 | 18204 | 5365 |
COQ8B,KLHL1,MTPN,MAP2K1,RERE,ZNF365,EZH2,TUBA1A,OPHN1,CLP1,WNT7A,HSPA5,COMT,SLC25A46,LDB1,CDK5,UQCRQ,PTPN11,NEUROD2,CBLN1,ARCN1,TRNP1,PROX1,CEND1 |
| 7.949e-03 | -4.83 | response to nerve growth factor | biological process | GO:1990089 | 52 | 24 | 18204 | 5365 |
UBE3A,USP8,NTF4,GAD2,KCNC1,TAC1,ARPC3,EHD1,CSNK1E,TMEM108,RAP1A,EIF4A3,AKT1,CBL,CD2AP,ELAVL4,ACAP2,GRIA1,SHOC2,RAB35,NTRK3,STMN2,ARF6,NTRK2 |
| 7.949e-03 | -4.83 | Signaling by EGFR | REACTOME pathways | R-HSA-177929 | 364 | 136 | 10285 | 3229 |
ICOS,IL2RG,PIK3R2,DUSP6,FGF1,PPP2R5A,MDM2,YWHAB,CDC42,FGF23,PTEN,PSMA5,MET,PAQR3,PEBP1,PSMB3,SPTAN1,PDE1A,PPP2R5E,PIP5K1A,SRC,DUSP9,FRS3,PSMD10,PIK3AP1,FGF10,MOV10,MAP2K1,KRAS,RAP1B,TNRC6C,RAF1,FGF22,UBA52,WDR83,IL2RB,LAMTOR3,CAMK2G,FGF16,IER3,CUL3,PSMC1,VWF,PIP4K2C,LAMTOR2,PPP2CB,KIT,HRAS,GAB1,IL5,PIK3CA,AKT3,PEA15,PSMA6,AKT1,PSMD1,PSMB2,PSMB4,RASGRP3,SHC1,DUSP1,SEM1,CD86,PSMA1,PSMC3,TP53,PSMD4,PHB1,SPRED1,RPS27A,IL3,PIK3R1,AHCYL1,PSMB1,PSMD3,CREB1,JAK2,PSMB7,CDKN1B,PSMC4,PSMA3,PSMB5,ADCY3,PSMB11,IL2,PSMC5,FGFR1,PSMB10,PSMA4,DLG4,CD28,CSK,BRAP,PSMA2,PSMB6,ADCY2,PDE1B,PSME1,ANGPT1,SPTBN1,AGO1,PPP5C,PSMD7,FGF17,CD80,PTPN11,PSMD14,UBB,CBL,PPP2R1A,PRKACB,PRKCA,CDKN1A,PRKCE,PIK3R3,CSF2,PSMD12,JAK1,FGF7,AKT2,RAP1A,SPRY1,SHC3,PSMD6,HBEGF,FGF3,PSME2,HGS,PSMB9,SPRED2,IL2RA,GSK3A,BAD,MAP3K11,DUSP10,NEFL |
| 7.950e-03 | -4.83 | PMVK (phosphomevalonate kinase) | protein interactions | 10654 | 98 | 39 | 19454 | 5460 |
UBXN6,SFN,ARL6IP6,HSPB8,CENPW,MLF2,FYTTD1,UPK1A,UBFD1,DDX1,ZNF177,CCNF,EEF1AKMT3,COMT,MPDU1,SCNM1,MCPH1,TRIM29,MBD5,ESR2,DUSP14,DDIT4L,SETD3,SNRNP27,SOX2,DDX39A,GTF2E2,CCR1,PITPNA,RDH12,BAP1,LGI1,LSM12,KRAS,SLC25A32,HSCB,NF2,DNAAF10,SLC37A4 |
| 7.950e-03 | -4.83 | ORC4 (origin recognition complex subunit 4) | protein interactions | 5000 | 98 | 39 | 19454 | 5460 |
LACC1,CAPZA2,CA14,RPA2,SDC2,CTBP1,CCND1,IL1R2,PARM1,FBXO25,MCM6,CCL2,CD200,HSCB,AKAP12,KRAS,NPTN,LRRN4CL,PABPC1,XRCC5,ORC6,SNIP1,CD40,RPA3,NSDHL,BRD3,TSNAX,KPNA1,SPOP,MCM4,MCM3,VAMP5,SCN3B,ORC5,LRWD1,CDC5L,SYNGR1,PHB1,CD274 |
| 7.950e-03 | -4.83 | NFXL1 (nuclear transcription factor, X-box binding like 1) | protein interactions | 152518 | 98 | 39 | 19454 | 5460 |
STAU1,CDK20,FBXW7,HSCB,TOMM20,RCCD1,RPA3,LRRN4CL,NUBP2,TUBB4B,RPN1,RPA2,RNF8,TP53,CCDC47,ST7,KLRD1,SEC62,MGARP,TUBA1A,OTULINL,TUBB,SEC63,VIRMA,ESR2,RAMP3,TMPO,EGLN3,LMBR1L,CCNF,AIFM1,SARM1,SEC61B,ZDHHC15,NTRK3,CUL3,OST4,MYC,DDRGK1 |
| 7.950e-03 | -4.83 | DNAAF2 (dynein axonemal assembly factor 2) | protein interactions | 55172 | 98 | 39 | 19454 | 5460 |
STXBP1,LMO3,RAB6A,DDX39A,SNCB,ATP6V1C1,NCALD,GNAQ,MACROH2A2,RAB6B,SQSTM1,RAB5A,GPM6B,GRIA2,GPM6A,L1CAM,HMGB1,DNAAF10,CNTN1,CAMKV,LASP1,LCN9,SNAP91,HPCA,GNG2,CUL3,RAB2A,RAB3A,CDH13,CRMP1,STX1A,POU5F1,SYP,GNAO1,CYRIB,AIP,EGLN3,SNAP25,MAPRE2 |
| 7.950e-03 | -4.83 | DSC3 (desmocollin 3) | protein interactions | 1825 | 98 | 39 | 19454 | 5460 |
KRAS,FANCG,STX7,TMT1A,DDX39B,RHOU,IGF1R,HSPA8,PRKAG1,FGFR1,EZH2,JUP,MET,CCR1,TP53,RND2,OTULINL,SOX2,CDC42,RHOH,RHOJ,YES1,CTSB,ESR2,CAV1,HRAS,NRSN1,RHOB,YWHAZ,LAMTOR1,UBE2H,CSGALNACT1,NTRK3,PKP4,DPP4,ATG9A,MYC,CTNNB1,DNAJC5 |
| 7.957e-03 | -4.83 | GPM6B (glycoprotein M6B) | protein interactions | 2824 | 22 | 12 | 19454 | 5460 |
ARMC1,CLN8,SEC63,DHRS7,FAM162A,SLC6A4,ALG11,ESYT1,STOM,HAX1,STX1A,TM9SF1 |
| 7.957e-03 | -4.83 | FGD4 (FYVE, RhoGEF and PH domain containing 4) | protein interactions | 121512 | 22 | 12 | 19454 | 5460 |
VIRMA,LANCL1,PRKCA,NEFL,ACTB,CAPZA2,CCDC86,CDC42,DDX39A,CUL3,PDIA3,CTDSPL2 |
| 7.957e-03 | -4.83 | OR13G1 (olfactory receptor family 13 subfamily G member 1) | protein interactions | 441933 | 22 | 12 | 19454 | 5460 |
VPS26C,COMMD6,LTO1,SEMG2,COMMD2,COMMD9,CCDC22,MED29,BEND6,COMMD8,COMMD5,COMMD3 |
| 7.957e-03 | -4.83 | FGD2 (FYVE, RhoGEF and PH domain containing 2) | protein interactions | 221472 | 22 | 12 | 19454 | 5460 |
CSTA,CAND1,SDF2L1,RPS27L,MCM6,KLHL12,PIK3R1,RPRM,TMEM263,CDC42,MRPS28,HP1BP3 |
| 7.957e-03 | -4.83 | C6orf15 (chromosome 6 open reading frame 15) | protein interactions | 29113 | 22 | 12 | 19454 | 5460 |
PSMG3,PSMG2,SV2B,TIMM13,TIMM8A,SUFU,HSPA5,YTHDF1,PSMG4,HSPD1,TIMM8B,MAEA |
| 7.957e-03 | -4.83 | Tagap (T cell activation Rho GTPase activating protein) | protein interactions | 72536 | 22 | 12 | 19454 | 5460 |
CPSF2,BAG3,RCL1,AKAP8L,LMNA,DDX42,PPIH,FAM76B,WDR82,CPSF1,ARHGEF39,THOC1 |
| 7.957e-03 | -4.83 | ZDHHC11 (zinc finger DHHC-type containing 11) | protein interactions | 79844 | 22 | 12 | 19454 | 5460 |
FAM241A,EFNB1,TSPAN15,RETREG2,CREB3,TMEM14B,SRC,GPR37,ARL15,TRAF6,FGFR1,FAM241B |
| 7.957e-03 | -4.83 | GLCCI1 (glucocorticoid induced 1) | protein interactions | 113263 | 22 | 12 | 19454 | 5460 |
YWHAZ,YWHAB,CUL3,TP53,DYRK1B,XPO1,YWHAG,YWHAH,DYNLL1,RIGI,DYRK1A,SLC23A2 |
| 7.957e-03 | -4.83 | SNAPC3 (small nuclear RNA activating complex polypeptide 3) | protein interactions | 6619 | 22 | 12 | 19454 | 5460 |
XPO1,PIP5K1A,SNAPC2,NFKBIL1,LDLR,UBE3A,RB1,SNAPC1,ENO1,CEP57L1,KRAS,TTC4 |
| 7.957e-03 | -4.83 | KNDC1 (kinase non-catalytic C-lobe domain containing 1) | protein interactions | 85442 | 22 | 12 | 19454 | 5460 |
ANAPC4,LMNA,ATP5PO,XPO1,MYC,DYRK1B,CUL3,PGRMC1,PPP2R5A,DYRK1A,HNRNPL,PPP2R5E |
| 7.957e-03 | -4.83 | RBM38 (RNA binding motif protein 38) | protein interactions | 55544 | 22 | 12 | 19454 | 5460 |
ARHGEF6,RCHY1,MDM2,ESR2,RAF1,TOP3B,RBFOX2,DDX39A,ZCCHC9,TRIM68,PICALM,ECD |
| 7.957e-03 | -4.83 | PYGO1 (pygopus family PHD finger 1) | protein interactions | 26108 | 22 | 12 | 19454 | 5460 |
BCL9,ORC6,SSBP3,LHX2,SSBP4,LDB1,CTNNB1,LMO4,SSBP2,CSK,SPTBN1,PRMT6 |
| 7.957e-03 | -4.83 | Mtx2 (metaxin 2) | protein interactions | 53375 | 22 | 12 | 19454 | 5460 |
TMEM263,PHB1,CCDC127,VDAC2,CHCHD6,RMDN3,AP2M1,PHB2,VDAC1,CHCHD3,SAMM50,CARD19 |
| 7.957e-03 | -4.83 | SFMBT2 (Scm like with four mbt domains 2) | protein interactions | 57713 | 22 | 12 | 19454 | 5460 |
SCML1,SIAH1,HNRNPL,SMN1,VIRMA,SCML2,CLK1,PHC1,RBPJ,AKT1,LYPLA1,MOV10 |
| 7.957e-03 | -4.83 | SCARA5 (scavenger receptor class A member 5) | protein interactions | 286133 | 22 | 12 | 19454 | 5460 |
PSMB1,TSG101,CAND1,UST,EHHADH,TMEM208,SLC35B4,DDX39A,NTAQ1,FBXO7,TXNIP,EXOC8 |
| 7.957e-03 | -4.83 | IL1A (interleukin 1 alpha) | protein interactions | 3552 | 22 | 12 | 19454 | 5460 |
EP300,CDK9,NDN,IL1RAP,IL1A,KPNA6,TP53,CAPN1,IL1R2,HAX1,COP1,EZH2 |
| 7.957e-03 | -4.83 | Ranbp1 (RAN binding protein 1) | protein interactions | 19385 | 22 | 12 | 19454 | 5460 |
COMMD8,PGAP2,RAN,COMMD3,XPO1,COMMD5,COMMD2,COMMD9,VPS26C,COMMD6,CCDC22,TFIP11 |
| 7.962e-03 | -4.83 | general transcription initiation factor activity | molecular function | GO:0140223 | 54 | 25 | 18094 | 5411 |
GTF2F2,GTF2E2,GTF2B,SNAPC5,GTF3C4,TAF7,SNAPC3,GTF2E1,TAF11,CCNH,GTF2H4,SNAPC1,GTF2A2,TAF2,GTF2H2,TAF10,DRAP1,TAF9,GTF2F1,RRN3,GTF3C3,PAAF1,DR1,GTF2A1,SNAPC2 |
| 7.963e-03 | -4.83 | JUNB (JunB proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 3726 | 110 | 43 | 19454 | 5460 |
PPP1R12A,BCL7B,ATF3,FOS,SAT1,FBXO11,DDIT3,EP300,RUVBL1,EGR1,BCL2A1,UTP25,BCL6,NDE1,TOP3B,NEU1,BATF,JUN,EIF3J,NFE2L1,DET1,TUBB4B,EIF1AX,SMAD3,PARP2,UBE2I,INTS12,COPS7B,PRNP,SMURF1,JUNB,CREBBP,MYC,PKIA,COPS7A,ATF4,TPM3,ATF1,FOSL2,SMAD4,BRCA1,COP1,TRIB1 |
| 7.970e-03 | -4.83 | PIGU (phosphatidylinositol glycan anchor biosynthesis class U) | protein interactions | 128869 | 101 | 40 | 19454 | 5460 |
ESR2,RAMP3,IFI6,THY1,RAC2,AP1G2,SEC61B,GPR173,HSD17B11,PRSS8,SYNGR1,EDNRA,PIGK,CDH13,RHOG,GPR17,HS2ST1,FKBP8,LPAR1,KRAS,GAL3ST1,VIPR1,TSPAN17,TSPAN15,PML,GPAA1,RNF121,CRELD1,GPR35,STOM,SSR1,RPN1,VAPB,KLRC2,GLRA2,YIPF3,SEC62,OTULINL,DNAJC25,CCDC47 |
| 7.971e-03 | -4.83 | C1orf35 (chromosome 1 open reading frame 35) | protein interactions | 79169 | 298 | 103 | 19454 | 5460 |
NUFIP2,MFAP1,GKAP1,UFL1,FXR2,YTHDF1,COIL,SAP18,CDSN,FTL,NKAPD1,RAB5A,RCL1,CDKL2,MYC,CUL3,STAC3,RIOK2,SNRNP40,ESR2,TACO1,CMTR1,AP2M1,SF3B4,GTF2F1,RAF1,SAR1B,RPL31,RINT1,FAM76B,PICK1,MKLN1,EWSR1,MRPS11,ARMC8,GAS8,DDRGK1,FAM98A,TNIK,SRSF1,S100A8,WDR82,SDCBP,TOX4,HEXIM1,RPLP0,ATG16L1,GABRA1,DENND2D,CFTR,NF2,FBXW7,PML,RNF113A,MECP2,RC3H2,TRIM23,UBE2H,RPL7A,CEP70,NDN,ZNF622,TRIM54,RAB14,PPP1R10,SRPK2,CCNF,PSPC1,EIF2AK2,METAP2,CTTN,CSNK2B,PRKRA,FGFBP1,CALML5,RBMX2,DDX42,RP9,TAF2,NAA35,RPSA,THAP1,CAMKV,TRIM63,MEPCE,RIGI,SNIP1,GLUL,SNRNP70,NOS1AP,RPS2,BRD3,PPIL4,CSNK2A1,PLEKHF2,TOP1,AKAP17A,CDK9,CD99L2,ZBTB2,ARL10,NAA30,ARL4D |
| 7.971e-03 | -4.83 | ELOVL2 (ELOVL fatty acid elongase 2) | protein interactions | 54898 | 60 | 26 | 19454 | 5460 |
ARF6,HSD17B11,SEC61B,PTPN1,RAB35,FXYD6,RHOG,LMNB1,ESYT1,LAMP3,LAMP2,RAB5C,GPR17,TSPAN10,STX7,CERS2,LPAR1,RAB9A,RUSF1,TMT1A,RPN1,SSR1,SEC62,CDC42,ST7,FAM234A |
| 7.971e-03 | -4.83 | RPP25 (ribonuclease P and MRP subunit p25) | protein interactions | 54913 | 60 | 26 | 19454 | 5460 |
MOB3C,MTA2,POP5,RPP21,LDOC1,DDI1,MEPCE,RPP14,NPM3,UFL1,AKAP1,SAT1,PICK1,PEBP1,KLHL22,DDRGK1,LRRC73,USP13,MYC,TCEAL7,IFI6,RPP25L,STAT1,SF3B4,POP7,PNMA1 |
| 7.971e-03 | -4.83 | SH3PXD2B (SH3 and PX domains 2B) | protein interactions | 285590 | 60 | 26 | 19454 | 5460 |
HSPA8,MRPS18C,FTL,KRAS,STAU1,LZTFL1,MND1,NEK7,FASLG,TOP3B,ATP5PB,CMPK1,KBTBD4,TP53,GPBP1L1,BORCS8,TRIM36,ACAA2,FGFR1,EIF2AK2,CBX5,VIRMA,TSC22D3,YWHAH,BICD2,NCK1 |
| 7.971e-03 | -4.83 | NTSR1 (neurotensin receptor 1) | protein interactions | 4923 | 60 | 26 | 19454 | 5460 |
VIRMA,RAMP3,B4GALT3,TNFSF18,ATP5F1B,GPR89A,SLC1A1,SCAMP2,ARL10,QNG1,FITM2,LACRT,ATP1A3,SLC30A5,ATP5F1A,SCN3B,CERS6,SLC6A8,TSPAN5,VIPR1,ATP5PF,LMBRD2,SURF4,KLRD1,TOP3B,ATP5PB |
| 7.971e-03 | -4.83 | PSD3 (pleckstrin and Sec7 domain containing 3) | protein interactions | 23362 | 60 | 26 | 19454 | 5460 |
GJA1,RAC2,RAB35,EEF1AKMT3,DIRAS3,VIRMA,CAV1,ARF6,RHOJ,YWHAH,LAMP3,YWHAG,DNAJC5,RAB2A,RAB11A,YWHAB,LAMTOR1,RHOG,RHOB,YWHAZ,ZYX,FLOT1,KRAS,CDC42,MX1,TP53 |
| 7.975e-03 | -4.83 | INTS7 (integrator complex subunit 7) | protein interactions | 25896 | 107 | 42 | 19454 | 5460 |
NHERF1,RPA2,PIH1D1,TANK,KIF1C,TOR1AIP2,SUPT5H,CA8,CD14,RPAP2,SOX2,FAF2,PPP2R1A,MGARP,DCP2,SEM1,KRAS,TNFSF8,SSRP1,TRIM52,PML,RPA3,PDCD1,CD226,RIT1,HNRNPD,NTRK3,SCN3B,VPS26A,FBXO7,RALA,BUB3,ESR2,POLR2B,CD1A,SSBP1,CD79B,LMBR1L,SYNCRIP,POLR2F,INTS10,TMEM74 |
| 7.975e-03 | -4.83 | BMP1 (bone morphogenetic protein 1) | protein interactions | 649 | 107 | 42 | 19454 | 5460 |
RANBP10,RAD21,HSPA5,PAEP,ADIPOQ,GREM2,GPIHBP1,MKLN1,CST11,RMND5B,DVL2,GID4,MAEA,GID8,NBN,ADRA1A,NCR3,ADAMTS1,CCL3,CBLN4,PI15,TP53,CSTF3,OS9,FIBIN,DNAJB9,INA,TWSG1,DNASE1L1,ELSPBP1,ARMC8,IGFBP4,SDF2L1,MSMB,PRKACB,LCN6,GGH,KLHL22,CALR,ZMYND19,CFC1,MSTN |
| 7.978e-03 | -4.83 | protein kinase inhibitor activity | molecular function | GO:0004860 | 73 | 32 | 18094 | 5411 |
YWHAG,CAMK2N1,YWHAB,SPRED1,CAMK2N2,HYAL2,HSPB1,AKT1,CDKN2C,CDKN1B,SPRED2,GSKIP,HEXIM2,CAV1,CHP1,PPP1R1B,PKIG,PKIA,LILRB4,HEXIM1,SH3BP5L,CDKN1A,MACROH2A1,NCK1,PKIB,TESC,DNAJC3,DUSP19,SOCS3,TRIB1,SFN,CDKN2D |
| 7.978e-03 | -4.83 | COG4 (component of oligomeric golgi complex 4) | protein interactions | 25839 | 104 | 41 | 19454 | 5460 |
OPRM1,GPR17,RSPH1,INSYN1,MUL1,LAMTOR1,CHRM4,CD274,SCN2B,TRIM45,RPS20,KRT8,PSMC5,COG1,CHP1,CAV1,FAM118B,ILVBL,APLNR,COMMD8,COMTD1,FAM234A,OTULINL,CDC42,NPY2R,CA14,RPA2,SIGLECL1,FKBP10,TMT1A,RPA3,CD40,RAB9A,RAB30,FARSA,SEMA4C,TRIM37,NDUFS2,PSMA1,KRAS,NPTN |
| 7.978e-03 | -4.83 | HUNK (hormonally up-regulated Neu-associated kinase) | protein interactions | 30811 | 104 | 41 | 19454 | 5460 |
USP8,MCHR1,PITHD1,SNRNP48,CLU,COPS4,TOMM6,CCAR1,TRAPPC1,DLAT,PICK1,TRIM68,CAMK1,CTDSP1,ANXA7,DDX39A,ATP5F1B,TRAPPC6B,LURAP1,DLST,STUB1,AIP,ASPA,ZNF655,TRAPPC10,SNRNP70,TRAPPC14,H1-1,ZNF343,TRAPPC4,VCPIP1,NAPA,AKAP8L,NEUROD2,SLC6A1,CXXC5,DIS3L,MGAT5B,COPS5,OLR1,SMARCE1 |
| 7.978e-03 | -4.83 | PTP4A1 (protein tyrosine phosphatase 4A1) | protein interactions | 7803 | 104 | 41 | 19454 | 5460 |
BOLA1,TNFAIP8,CMSS1,PSMD3,TMED5,ACOT8,GRSF1,GMPS,CNNM4,PSMD1,MBLAC2,FBXO22,MACROD1,G6PD,TUBA1B,MRTO4,RPS12,LDLR,LHFPL4,PSMC5,PREP,MRPS28,NUDT12,GINS4,PTP4A2,RPA2,NUDT16,FDFT1,ARL15,PRKAB1,FNTB,CD59,GNL1,PDHB,POLDIP2,RIGI,RNF11,GINS3,RPA3,UNC50,RABGGTB |
| 7.978e-03 | -4.83 | FBXL4 (F-box and leucine rich repeat protein 4) | protein interactions | 26235 | 104 | 41 | 19454 | 5460 |
ERLEC1,STK38,VDAC1,FBXL4,PXMP2,SKP1,BNIP3L,HSPA5,LPCAT3,FKBP8,LYG2,HSPD1,CCT8,HSPA8,MAVS,AKAP1,PDIA6,TUBB4B,DUSP14,TXNRD1,MTCH2,CRAT,FAF2,TTC9C,ACTB,LGALS3,GPNMB,TRIM29,TUBB,TOMM70,HSP90AB1,VIRMA,AIFM1,TUBA1B,CCT2,PPM1B,FIS1,HSP90AA1,PDIA3,SLC25A46,XPO1 |
| 7.978e-03 | -4.83 | GRK2 (G protein-coupled receptor kinase 2) | protein interactions | 156 | 104 | 41 | 19454 | 5460 |
RCVRN,AKAP12,ADRB2,STAU1,PPWD1,FBXO25,RIGI,CCR4,PEBP1,CCR5,PRPF4,PRKCB,PIK3CG,PLCB1,GIT2,PRKCA,CAPN2,PDCL,ACACA,GNAQ,VDR,TRAF2,KCNIP3,GRM1,FERMT2,MDM2,CAV1,GNB1,SRC,HSP90AB1,SLAIN2,GNB3,CSNK2B,RPLP2,BICD2,EPHA2,HSP90AA1,MOV10,GPR17,PAPOLA,HDAC6 |
| 7.978e-03 | -4.83 | TNF_CS | interpro domains | IPR021184 | 12 | 8 | 18521 | 5414 |
FASLG,TNFSF13,TNFSF10,CD40LG,LTA,TNFSF8,LTB,TNF |
| 7.978e-03 | -4.83 | Band_7/SPFH_dom_sf | interpro domains | IPR036013 | 12 | 8 | 18521 | 5414 |
ERLIN2,PHB2,STOML3,STOML2,FLOT1,PHB1,ERLIN1,STOM |
| 7.979e-03 | -4.83 | third_ventricle | COSMIC cancer mutations | third_ventricle | 45 | 21 | 16828 | 4835 |
TP53,NACC2,GNA11,KIT,MET,CTNNB1,PPP2R1A,FBXW7,IDH2,PTPN11,AKT1,PIK3CA,FGFR1,PTEN,SMARCB1,HRAS,KRAS,CDH8,IDH1,CLCN6,GNAQ |
| 7.979e-03 | -4.83 | protein heterodimerization activity | molecular function | GO:0046982 | 329 | 119 | 18094 | 5411 |
GADD45A,CAV1,TENM3,POLE4,H2AJ,H2BC12,BHLHE40,ADRA1A,H2AZ1,UBA3,H2BC9,H2AC6,ATP1B1,ATP1A2,TP53,RALGAPA2,GABBR1,NAE1,BUD23,MEF2C,TAF9,H2BC14,SLC51A,VAPB,FXR2,PPP2R1A,POLE3,H2AC13,PDSS2,H2AZ2,IL12B,RRAGA,TUBA1A,HEXA,SNX1,ALG2,ATF3,PRMT5,P2RY1,TCOF1,ADORA1,PHB2,PAFAH1B3,UGT1A1,DDIT3,SDCBP,H3C1,XBP1,LSM6,BAK1,MACROH2A1,H2AC1,RAN,IKBKB,SUPT4H1,H2AC25,MEF2A,IL17F,H2BW1,CAV2,FZD4,PAFAH1B2,TAF11,H2AC4,FBXO7,H2AX,GCA,SOS2,IL12A,PAFAH1B1,CD247,SRI,CHRAC1,SUPT3H,SLC7A8,MCL1,SNX2,H2BC17,DRAP1,ROPN1B,H2BC11,PHB1,ADD1,PIK3R1,MAPK4,EXT1,ZHX1,CENPW,GTF2A1,QTRT2,TLR4,H2AC7,BHLHA9,DR1,ADRB1,SUPT7L,ZHX3,MACROH2A2,H2AB1,KCNB1,TAF7,ADD2,LSM5,NEUROD2,ATF4,GPHA2,GTF2A2,YWHAH,H2BC1,ATP1A1,NFYB,PIK3R2,TRMT112,TLR6,BOK,SUPT5H,BAX,SLC7A9,NR4A2 |
| 7.992e-03 | -4.83 | adenosine 5'-monophosphoramidase activity | molecular function | GO:0043530 | 4 | 4 | 18094 | 5411 |
FHIT,HINT2,HINT1,HINT3 |
| 7.992e-03 | -4.83 | thrombospondin receptor activity | molecular function | GO:0070053 | 4 | 4 | 18094 | 5411 |
SDC4,CD36,CD47,F2 |
| 7.992e-03 | -4.83 | uridine kinase activity | molecular function | GO:0004849 | 4 | 4 | 18094 | 5411 |
UCK2,CMPK1,UCKL1,UCK1 |
| 7.992e-03 | -4.83 | very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity | molecular function | GO:0102158 | 4 | 4 | 18094 | 5411 |
HACD4,HACD2,HACD1,HACD3 |
| 7.992e-03 | -4.83 | cytidine kinase activity | molecular function | GO:0043771 | 4 | 4 | 18094 | 5411 |
DCK,UCKL1,UCK1,UCK2 |
| 7.992e-03 | -4.83 | Toll-like receptor 2 binding | molecular function | GO:0035663 | 4 | 4 | 18094 | 5411 |
TLR6,TLR1,TIRAP,TLR10 |
| 7.996e-03 | -4.83 | ADGB (androglobin) | protein interactions | 79747 | 6 | 5 | 19454 | 5460 |
H1-1,IK,H2AC4,RAF1,H1-5 |
| 7.996e-03 | -4.83 | EXTL1 (exostosin like glycosyltransferase 1) | protein interactions | 2134 | 6 | 5 | 19454 | 5460 |
FNDC9,SDR16C5,TMEM237,TMEM14B,CLDN9 |
| 7.996e-03 | -4.83 | Eif4a1 (eukaryotic translation initiation factor 4A1) | protein interactions | 13681 | 6 | 5 | 19454 | 5460 |
PTEN,YTHDF1,RBFOX2,STUB1,CCNF |
| 7.996e-03 | -4.83 | ATP8B1 (ATPase phospholipid transporting 8B1) | protein interactions | 5205 | 6 | 5 | 19454 | 5460 |
HNRNPL,CSK,TMEM30A,DDX39A,VIRMA |
| 7.996e-03 | -4.83 | CXorf58 (chromosome X open reading frame 58) | protein interactions | 254158 | 6 | 5 | 19454 | 5460 |
H2BC9,GDE1,DCAF5,CSK,TGFBR2 |
| 7.996e-03 | -4.83 | GDF6 (growth differentiation factor 6) | protein interactions | 392255 | 6 | 5 | 19454 | 5460 |
SMAD5,SMAD1,BMPR2,BMPR1A,BMPR1B |
| 7.996e-03 | -4.83 | SGD1 (Sgd1p) | protein interactions | 851049 | 6 | 5 | 19454 | 5460 |
STAC3,FXR2,KLHL12,CEP70,COIL |
| 7.996e-03 | -4.83 | Nrk (Nik related kinase) | protein interactions | 27206 | 6 | 5 | 19454 | 5460 |
BAG2,HSP90AB1,HSPA8,HSP90AA1,STUB1 |
| 7.996e-03 | -4.83 | Map2k3 (mitogen-activated protein kinase kinase 3) | protein interactions | 26397 | 6 | 5 | 19454 | 5460 |
SMAD3,BMPR1B,SMAD4,SMAD2,SMURF1 |
| 7.996e-03 | -4.83 | nef (nef protein) | protein interactions | 1490008 | 6 | 5 | 19454 | 5460 |
ELOC,UBE3A,EED,TP53,CBFB |
| 7.996e-03 | -4.83 | Insr (insulin receptor) | protein interactions | 16337 | 6 | 5 | 19454 | 5460 |
IGF1R,FAF2,CLK1,NSFL1C,PDIA3 |
| 7.996e-03 | -4.83 | CSMD1 (CUB and Sushi multiple domains 1) | protein interactions | 64478 | 6 | 5 | 19454 | 5460 |
SPPL3,HNRNPL,BCL6,VIRMA,HNRNPA1 |
| 7.996e-03 | -4.83 | ZNF793 (zinc finger protein 793) | protein interactions | 390927 | 6 | 5 | 19454 | 5460 |
RSPH1,HNRNPL,CUL3,TIAM1,TULP3 |
| 7.996e-03 | -4.83 | ADRB3 (adrenoceptor beta 3) | protein interactions | 155 | 6 | 5 | 19454 | 5460 |
ARRDC3,CFTR,SRC,ADRB3,ADRB2 |
| 7.996e-03 | -4.83 | SLC36A1 (solute carrier family 36 member 1) | protein interactions | 206358 | 6 | 5 | 19454 | 5460 |
PTTG1,DDX39A,RIGI,PTEN,LGALS8 |
| 7.996e-03 | -4.83 | ELAPOR2 (endosome-lysosome associated apoptosis and autophagy regulator family member 2) | protein interactions | 222223 | 6 | 5 | 19454 | 5460 |
VIRMA,SIGLECL1,LAMTOR1,SDC2,PRNP |
| 7.996e-03 | -4.83 | MEDAG (mesenteric estrogen dependent adipogenesis) | protein interactions | 84935 | 6 | 5 | 19454 | 5460 |
HSP90B1,TOLLIP,CATIP,SYNJ2BP,ATPAF2 |
| 7.996e-03 | -4.83 | WNT9B (Wnt family member 9B) | protein interactions | 7484 | 6 | 5 | 19454 | 5460 |
NDUFA2,MGMT,HECTD3,ZMYM3,HSPA5 |
| 7.996e-03 | -4.83 | S (spike protein) | protein interactions | 14254594 | 6 | 5 | 19454 | 5460 |
CEACAM5,TFRC,DPP4,SFTPD,HSPA5 |
| 7.996e-03 | -4.83 | SMIM14 (small integral membrane protein 14) | protein interactions | 201895 | 6 | 5 | 19454 | 5460 |
SGTA,FATE1,SLPI,TMEM42,LSM4 |
| 7.996e-03 | -4.83 | Mapk1 (mitogen-activated protein kinase 1) | protein interactions | 26413 | 6 | 5 | 19454 | 5460 |
BCL2L1,NR4A2,CCNF,PTPN5,TP53 |
| 7.996e-03 | -4.83 | CYP39A1 (cytochrome P450 family 39 subfamily A member 1) | protein interactions | 51302 | 6 | 5 | 19454 | 5460 |
HERC3,GLUL,SPPL3,SMYD3,SERINC1 |
| 7.996e-03 | -4.83 | Nos1 (nitric oxide synthase 1) | protein interactions | 24598 | 6 | 5 | 19454 | 5460 |
DLG4,DYNLL1,STUB1,NOSIP,HSP90AA1 |
| 7.996e-03 | -4.83 | ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif 18) | protein interactions | 170692 | 6 | 5 | 19454 | 5460 |
ELAVL4,HSPA5,SRPK2,ALB,CSK |
| 7.996e-03 | -4.83 | LOC102724652 (crystallin alpha A2) | protein interactions | 102724652 | 6 | 5 | 19454 | 5460 |
NTAQ1,GORASP2,SPG21,SDCBP,CRYAB |
| 7.996e-03 | -4.83 | PGBD5 (piggyBac transposable element derived 5) | protein interactions | 79605 | 6 | 5 | 19454 | 5460 |
PIP5K1A,RMDN3,RABGGTB,FTL,VIRMA |
| 7.996e-03 | -4.83 | EBNA-2 (nuclear antigen EBNA-2) | protein interactions | 3783761 | 6 | 5 | 19454 | 5460 |
CREBBP,CDK1,RBPJ,SMARCB1,ZMYND11 |
| 8.040e-03 | -4.82 | UBIQUITIN_2 | prosite domains | PS50053 | 52 | 23 | 12186 | 3388 |
UBTD1,USP14,UBLCP1,SUMO1,DDI1,NEDD8,UBL3,FAU,TBCEL,ISG15,SUMO2,UBB,RBCK1,UBA52,RAD23B,UBFD1,RPS27A,SUMO3,TMUB1,UBL4A,UBTD2,SF3A1,TMUB2 |
| 8.084e-03 | -4.82 | NEK7 (NIMA related kinase 7) | protein interactions | 140609 | 159 | 59 | 19454 | 5460 |
PCNA,PDIA6,NEK9,OLA1,TNF,WDR19,HSPE1,HADH,EEF2,CMPK1,RANBP1,SUPT5H,NHERF1,DNAJC2,GDI2,UBE2N,TMPO,TTC9C,EIF2S1,CPNE1,SUMO2,LAMP3,GLO1,DDX1,AHSA1,AK2,FKBP4,PGK1,P4HA2,PRDX6,DPH3,SLC39A9,RPA3,XRCC5,G3BP2,SMC4,TIMM29,NEK7,UBE2M,PCLAF,HSP90B1,GANAB,PSPC1,CCNF,APLNR,APEX1,SRPK2,DYNLL1,MCM3,GGH,CSK,TNFAIP3,MYC,ACO2,SUB1,PYCARD,CUL3,NLRP3,PSMD14 |
| 8.084e-03 | -4.82 | CEP57 (centrosomal protein 57) | protein interactions | 9702 | 159 | 59 | 19454 | 5460 |
SSBP1,FABP5,KRT8,RPLP2,RPS16,SPTAN1,TSPYL4,DHX15,MRPS23,TEX12,PRPF19,HDAC6,CSNK2A1,CSTA,LSM3,LYZ,RPL23,HSPB1,HNRNPA2B1,MRPS11,KRAS,RPS4X,RIGI,HINT3,RPS7,DISC1,FBXL3,RPS11,MRPL49,TBC1D4,RPS23,RPS3,FBLN5,TNFRSF1B,UBB,RPL22,MYC,EMILIN1,RPS17,PRKACB,PHKA1,GCC1,SH3BP5L,HSP90AA1,CCHCR1,ATPAF2,MIA2,SLC31A1,KDM1A,OIP5,MRPL40,MRPS7,FTL,HSPA5,RPS14,CCND1,FTH1,LMO3,TFIP11 |
| 8.084e-03 | -4.82 | COG6 (component of oligomeric golgi complex 6) | protein interactions | 57511 | 159 | 59 | 19454 | 5460 |
KLC2,MFAP1,VPS54,NDUFA5,NPY2R,CFTR,LMO4,PTAR1,NUP62,FAM234A,NPTN,CD40,CCHCR1,BICD2,PSMD14,CCDC22,NTAQ1,EXOC5,RNF40,SNRPB,SYCE3,GPR17,NCKAP1,SCN2B,UFSP1,SCNM1,TMSB4X,GRAP2,STX12,TRAPPC13,CYB5B,IFT57,RAB6B,SNAPIN,SPG21,SNAP29,COMTD1,COMMD8,RNF20,FANCG,ZBTB16,PSMA1,BLOC1S2,OAS1,POC1B,ATP6V1D,TSNAX,BCL10,CCDC92,TRAF6,GAS8,EXOC1,FNDC11,ILVBL,STX6,PPP1R18,COG1,XPO5,PSMB1 |
| 8.090e-03 | -4.82 | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | 37 | 18 | 16828 | 4835 |
AKT1,PTPN11,PPP2R1A,FBXW7,IDH2,CTNNB1,MET,GNA11,KIT,NACC2,PTEN,FGFR1,PIK3CA,IDH1,KRAS,HRAS,GNAQ,CLCN6 |
| 8.126e-03 | -4.81 | LMF1 (lipase maturation factor 1) | protein interactions | 64788 | 46 | 21 | 19454 | 5460 |
HS2ST1,HNRNPL,LYZL6,LYPD6,B4GALT3,NDST3,NUDT9,BRINP2,SPINT2,TMEM30A,CHRNB2,ITGB8,OGFOD3,TAFAZZIN,GP9,SFTPC,SERPINB11,CLEC2B,FUT9,TOR3A,NXPH3 |
| 8.126e-03 | -4.81 | TM9SF1 (transmembrane 9 superfamily member 1) | protein interactions | 10548 | 46 | 21 | 19454 | 5460 |
S1PR4,LMBR1L,MME,TSPAN15,TCOF1,VIPR1,GPM6B,SLC1A1,RTN4,RNASEH1,LPAR1,SRPRB,DUOXA2,RIGI,OPRL1,ESR2,B3GNT2,ICAM2,ATP1B1,LMNA,PLD3 |
| 8.126e-03 | -4.81 | AKAP7 (A-kinase anchoring protein 7) | protein interactions | 9465 | 46 | 21 | 19454 | 5460 |
SNRPE,USP15,PRKCA,LSM3,LSM6,RPS6KA4,SNRPB,PRKACB,URM1,ALG11,SNRPN,CSK,SNRPG,SEC63,MEPCE,SNRPD3,LSM5,LSM4,CTU1,SNRPD2,PRPF4 |
| 8.128e-03 | -4.81 | neuromuscular junction | cellular component | GO:0031594 | 75 | 32 | 19108 | 5553 |
SYNGR4,DNAJC5,TUBA1A,TBC1D24,LARGE1,NLGN1,DLG4,SPOCK1,SYNGR2,ASCC1,LAMB2,GRIA1,DLG3,DES,CD2AP,FCHSD2,CAV3,SYNGR1,CIB2,DLGAP4,PSEN1,CDK5,SYP,NEFL,DLG1,SNTA1,EPHA4,TRIP4,SYNGR3,ACHE,CRKL,CDK5R1 |
| 8.145e-03 | -4.81 | Sm core complex | KEGG pathways | M00398 | 7 | 6 | 7161 | 2463 |
SNRPD3,SNRPG,SNRPE,SNRPB,SNRPD1,SNRPD2 |
| 8.145e-03 | -4.81 | Sm core complex | KEGG pathways | hsa_M00398 | 7 | 6 | 7161 | 2463 |
SNRPD1,SNRPD2,SNRPE,SNRPG,SNRPD3,SNRPB |
| 8.145e-03 | -4.81 | Lsm 2-8 complex | KEGG pathways | M00396 | 7 | 6 | 7161 | 2463 |
LSM2,LSM5,LSM6,LSM4,LSM3,LSM8 |
| 8.145e-03 | -4.81 | Lsm 2-8 complex | KEGG pathways | hsa_M00396 | 7 | 6 | 7161 | 2463 |
LSM2,LSM5,LSM8,LSM3,LSM6,LSM4 |
| 8.161e-03 | -4.81 | negative regulation of RNA biosynthetic process | biological process | GO:1902679 | 1271 | 413 | 18204 | 5365 |
PSMD10,RIOX2,SUPT5H,MDFI,APOBEC3B,SDR16C5,NDN,NAB1,SPINDOC,ZBTB45,FBXW11,EID2,PHF12,RB1,CITED1,DAP,ZHX3,TFDP2,LDB1,FOXC2,H1-5,CGGBP1,TNF,ADIPOQ,RBBP7,LBH,HMGA1,NAB2,FERD3L,YAF2,XCL1,RBPJ,SRSF2,BRMS1L,CBX5,MSX1,NKX6-2,TAGLN3,PHB1,ING1,TRIM6,FOXP4,CXXC5,HMG20A,HMGB1,HEXIM2,CDK5,BCL6,PFDN5,HINFP,GABPA,FBP1,KDM2A,PKIA,ZNF304,EPO,ZNF668,ZNF692,NR4A2,ZBTB14,CNOT7,EGR1,ESR2,EZH2,EZH1,CDKN1B,IMPACT,BTG2,ZBTB6,SUFU,SUV39H1,SLA2,PPARG,MIDEAS,RBM15B,RPL23,APOBEC3H,TAF7,MDM2,SDCBP,TP53,MAEL,ZNF451,VPS72,MITF,PCGF6,UBE2D3,DDX5,PCGF2,HELT,SAP18,FGFR1,ATXN1L,NKAP,HSPA8,SIX5,PAX9,TGIF2LX,KLF4,DDIT3,TRIM27,POLE3,CDK6,NONO,IRF7,KDM1A,NR1I2,ZBTB26,MACROH2A1,TRIM29,CTBP1,HDAC5,PRMT2,IRF8,SHC1,ZNF174,TOB2,SAP30L,TWIST2,SUMO1,RGN,TADA3,DHRS7B,TRIM22,SOX9,DICER1,SNAI2,IGBP1,DLG1,MAFG,IKZF5,NOTCH2,RLIM,RERE,RING1,PCNA,OTUD7B,MXD1,NCK1,TLE1,ZBTB38,SOX2,TRIM37,GCLC,IRF2,HSBP1,DKK1,THAP7,STAT6,RNF8,ZNF177,ZNF345,ZBTB18,GREM1,HCFC2,MBD3,MTDH,CREBBP,PROX1,BHLHE40,RBBP8,TRIM11,CAV1,MEPCE,RBFOX2,ZBTB17,CBFB,VGLL4,ING2,RUVBL2,DKK3,BEND5,LANCL2,MEF2C,RUNX1,ZMYM2,GFI1,THAP1,BEND6,PKIG,BRCA1,IL4,WWP1,SMAD2,ZHX1,ZGLP1,APOBEC3F,UBE2I,PSEN1,NKRF,LILRB4,SCML1,ZBTB42,RORB,WWP2,DLX1,RPS14,MOSPD1,FLCN,SFRP1,CREB1,MAGEH1,MYC,CRYAB,APOBEC3G,APOBEC3D,HNF1B,ID1,OSR2,INPP5K,BARX2,EED,HEY2,IRF3,NFIL3,TGIF2,CSF2,SMAD5,KLF12,MAGED2,CDK5R1,HCLS1,PSPC1,PSMC5,IRF2BPL,PDE2A,CIART,POU1F1,PML,NFKB1,SNAI3,C1D,CD38,APOBEC3A,ZBTB25,TRAF6,GADD45A,PIAS1,ZBTB39,PLAGL1,XRCC5,MAGEB10,SCML2,NIF3L1,NR2F6,DUSP22,SMAD3,MAGEA4,RASD1,IRF2BP1,NR1I3,SETD5,KLF10,MACROH2A2,HNRNPL,NOG,HDAC6,SGF29,NKX3-1,MAGEB1,ATF3,CCAR2,APOBEC3C,DNAJB4,SOX3,NSMCE3,PRMT6,MECP2,VEGFA,DRAP1,MTA2,CCAR1,SATB1,NR0B1,CUL3,GTF2IRD1,NR2E1,YWHAZ,INSM2,MAGED4B,FOXP2,IRF1,BRMS1,NIBAN2,SOX14,CIPC,MYT1L,ELK4,IFI16,TCEAL7,CTNNBIP1,CRYM,ZBTB5,BIRC5,CBX7,APEX1,IFNG,MEF2A,SUPT4H1,PDCD4,HOXB8,ETV6,KLF3,CCDC85B,H1-3,SMARCA5,PPID,ELK3,HEXIM1,EID1,ZNF175,PHB2,FASLG,LEP,HNRNPK,SQSTM1,HNRNPA2B1,ATF4,MCPH1,PHC1,MAF1,TSG101,E4F1,NR1H2,USP3,STAT1,CRY1,DEDD,LMO4,CREBZF,PHF21A,HIRA,CCND1,NCOA5,AR,UBE2D1,TRIM24,CNOT2,SAP30,EP300,DR1,CALR,OVOL1,SIRT7,TCF23,VDR,TXN,MAX,BACH1,RBBP4,CTNNB1,SP2,CCND3,MXI1,GMNN,ZMYND11,EID2B,SIAH2,NOP53,DUSP26,PRMT5,SMAD4,PAX6,SIN3A,IFI27,MAD2L2,LYAR,TXNIP,WNT10B,FOXS1,ZBTB33,CD36,BAP1,FOXD3,TCF21,POU5F1,HDAC3,PLCB1,KCNIP3,RPL10,ZBTB16,ZNF24,E2F6,MSX2,WDR82,SFN,DNAJB6,NACC2,FABP4,IFNA2,CDC73,NKX3-2,FOXP1,MAGEC2,LDB2,ID4,RFX5,ZBTB2,USP2,SOX21,BAHD1,COPS2,JUN,MORC2,DMAP1,CBX3,HMX1,ENO1,FOXP3,ZNF263,MTA3,PPARA,SMARCE1 |
| 8.164e-03 | -4.81 | skin-shoulder-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-shoulder-malignant_melanoma-superficial_spreading | 10 | 7 | 16828 | 4835 |
STK11,GNAQ,PIK3CA,KIT,HRAS,KRAS,CTNNB1 |
| 8.164e-03 | -4.81 | eye-conjunctiva-malignant_melanoma | COSMIC cancer mutations | eye-conjunctiva-malignant_melanoma | 10 | 7 | 16828 | 4835 |
TERT,GNAQ,IDH2,IDH1,GNA11,KIT,CTNNB1 |
| 8.164e-03 | -4.81 | central_nervous_system-supratentorial-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-supratentorial-primitive_neuroectodermal_tumour-medulloblastoma | 10 | 7 | 16828 | 4835 |
IDH2,PTEN,SMARCB1,IDH1,SUFU,TP53,CTNNB1 |
| 8.164e-03 | -4.81 | melanocytic_tumour | COSMIC cancer mutations | melanocytic_tumour | 10 | 7 | 16828 | 4835 |
KRAS,KIT,HRAS,GNA11,AKT1,GNAQ,BAP1 |
| 8.164e-03 | -4.81 | metaplasia | COSMIC cancer mutations | metaplasia | 10 | 7 | 16828 | 4835 |
TP53,STK11,CTNNB1,KRAS,SMAD4,SF3B1,PTEN |
| 8.164e-03 | -4.81 | skin-abdomen-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-abdomen-malignant_melanoma-superficial_spreading | 10 | 7 | 16828 | 4835 |
HRAS,KIT,KRAS,CTNNB1,PIK3CA,STK11,GNAQ |
| 8.164e-03 | -4.81 | small_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-carcinoma-adenocarcinoma | 10 | 7 | 16828 | 4835 |
IDH1,IDH2,SMAD4,KRAS,CTNNB1,STK11,TP53 |
| 8.174e-03 | -4.81 | positive regulation of leukocyte migration | biological process | GO:0002687 | 149 | 58 | 18204 | 5365 |
CXCL13,CCR2,AIF1,CCL19,PTN,PIK3R1,CCL21,RARRES2,TACR1,CCL1,CD99L2,SWAP70,IL23A,VEGFA,CCR1,MSTN,CXCL10,TNFRSF14,LGALS3,IL34,TIRAP,CCR6,OXSR1,CCL8,CCR7,TNFSF18,PYCARD,THY1,AGER,CREB3,CCL20,ITGA2,VEGFC,HMGB1,CCL3,RAC2,IL12A,CXCL12,P2RY12,CX3CR1,IL6,CCL24,MED23,SELENOK,F7,CD47,GPSM3,TNF,CXCL8,CCL5,ICAM1,DEFB124,CX3CL1,IL1A,MADCAM1,CALR,XCL1,MMP14 |
| 8.198e-03 | -4.80 | USP22 (ubiquitin specific peptidase 22) | protein interactions | 23326 | 156 | 58 | 19454 | 5460 |
PSME1,PABPC1,KLHL23,PREPL,MYO1B,LDLRAD4,CD1B,ZBED1,HEXA,CLEC2B,ACTR2,EZH2,TAF10,CYB5B,BIRC5,CD274,CCAR2,TCP1,AASDHPPT,DPP4,MOV10,ENY2,YWHAH,YWHAG,H2AC4,TAF9,CDC23,ARPC2,HADHA,MAVS,USP8,SGF29,KDM1A,FAM234A,MRPL10,SUPT3H,CDK1,RPA2,PPARG,CTDSP1,E2F6,SUPT7L,STAT1,VIRMA,SRC,CDC20,CUL3,CCNB1,IKZF2,TAF5L,MYC,DNAJC5,AR,RIC3,TADA3,TADA1,SCFD1,DEDD |
| 8.203e-03 | -4.80 | leukocyte migration | biological process | GO:0050900 | 245 | 90 | 18204 | 5365 |
ADD2,CXCL9,PAFAH1B1,CXCL8,CCL5,ICAM1,FCER1G,MADCAM1,ITGA6,ROCK1,IL6,CDC42,PPIA,MSMP,EXT1,CCL3,SRC,SCG2,ADORA1,PPIB,CCL11,CCL8,PIK3CG,PDE4B,EPS8,LEP,LGALS3,SRP54,SELL,PIK3R1,F11R,EMP2,CCL1,CD99L2,IRAK4,CXCL13,JAML,PTN,CXCL3,DPEP1,TNF,CX3CL1,TGFB2,IL10,XCL1,CX3CR1,DBH,CCL24,CXCL11,SELENOK,JAGN1,YES1,HMGB1,SYK,CH25H,IL1B,H2BC1,CCL23,CXCR1,CCR6,FOLR2,CCR7,S100A8,CXCR4,PLG,GPR15,CCL20,CXCL1,CXCL10,CCL2,B4GALT1,CCL18,CHGA,CCR1,CCL4L1,CD34,RPL13A,CKLF,CCL21,CCR5,CCL25,KIT,SLC12A2,CCR2,CCL19,SFTPD,ADGRE2,CRKL,NINJ1,MSN |
| 8.246e-03 | -4.80 | immune response-regulating signaling pathway | biological process | GO:0002764 | 368 | 130 | 18204 | 5365 |
PIK3AP1,TNFAIP3,FCGR2A,KLRC2,YES1,PHB1,LY96,EIF2B3,TNF,NFKBIA,EP300,CACNB3,CLPB,FCN2,FCGR2B,TLR6,NCR3,MAPK10,STK11,PYCARD,HRAS,CREBBP,NLRP1,PTPN22,MBL2,SYK,OTULIN,CD40,CACNB4,PRKCE,NFKB1,PRKCB,KCNJ8,FOSL2,LACC1,OAS1,TRAF3IP3,CGAS,FCGR1A,TLR7,IRF7,NLRP6,LSM14A,MAP2K6,CD200R1,TIRAP,PAK2,TLR5,TIFA,BECN1,CTLA4,MAPKAPK3,LAT2,TMEM126A,CRKL,UBE2N,TBK1,KLRD1,FCAR,CLEC12B,CD38,CD2AP,TLR10,TICAM2,KIT,TLR2,CD14,NLRP3,TRAF6,CLEC7A,CSK,SPG21,BAX,PIK3CA,STOML2,SPPL3,FCER1G,TLR3,FGR,IRF3,BTN2A2,PHB2,MICB,TLR4,RNF34,PDE4B,THY1,PLPP4,CD79B,LILRB1,BCL10,HSPD1,SRC,FOXP3,CD274,LILRA3,CD28,LILRA1,MOG,ITK,ATAT1,EIF2B2,MEF2C,TYROBP,RIGI,TICAM1,TLR1,VAV2,RC3H2,NMI,RBCK1,CLEC6A,MAVS,IKBKB,LCP2,FCMR,LILRA2,TLR8,PSEN1,EIF2B5,LILRB4,CD247,IL20RB,CD3G,TLR9,IFIH1,IRAK4,SLA2,PRKCQ,MYD88 |
| 8.250e-03 | -4.80 | ubiquitin-like protein ligase activity | molecular function | GO:0061659 | 369 | 132 | 18094 | 5411 |
STUB1,HERC3,TRIM10,TRIM27,MED30,RNF14,SYVN1,FBXO30,RNF148,ANKIB1,TRIM32,TRIM45,SHPRH,UBR7,HECW1,TRIM34,HUWE1,RNF39,GID4,RNF133,RNF7,MED31,ZNRF1,TRIM15,CDC42,TRIM8,PML,MSL2,RNF40,COP1,TRIM44,CUL3,RNF8,UBE2D1,TRIM37,TRIM62,TRIM11,HECTD1,TOPORS,MUL1,UBE2K,BFAR,RNF20,TRIM6,PRPF19,TRAF6,ASB1,RNF152,PPP1R11,RNF128,TRIM63,RNF113A,TRIM23,RNF144B,ATG3,RNF103,RING1,MED21,ZBED1,UBE3A,UBE2D3,NOSIP,MED27,CBL,NT5C2,MYLIP,UBE2A,VPS18,MAEA,TRIM26,RAG1,RNF208,RNF167,CCAR1,RNF115,BIRC2,RNF11,RC3H2,ANAPC11,TRIM5,UFL1,MED11,SIAH1,RLIM,WSB1,WWP2,CBLL1,RNF126,FBXO44,RNF41,MARCHF5,RNF10,TRIM35,TRIM68,RNF121,RNF146,TRIM54,UBE2F,NEURL2,RNF26,SMURF1,RMND5B,TRIM3,CDK8,RNF139,TRIM52,TRIM21,RNF5,AREL1,PIAS1,TRAF7,TRIM22,RCHY1,MED17,ZNF451,IRF2BP1,MDM2,BRAP,WWP1,EGR2,SIAH2,RNF34,MED10,RNF181,TRAF3IP2,TRIM24,PELI1,IRF2BPL,PELI3,PCGF3,HERC4,RNF122 |
| 8.255e-03 | -4.80 | H1-6 (H1.6 linker histone, cluster member) | protein interactions | 3010 | 206 | 74 | 19454 | 5460 |
DMAP1,LLPH,RBM34,H2BC1,FBP1,H2AX,H1-3,NOC4L,NUP42,SRSF12,MEPCE,IRAK4,H2BC14,UTP25,RPL31,NKRF,RPL3,RPS24,ZCCHC9,MRPL18,MPHOSPH10,H2AC4,RPS2,NOL12,POU5F1,RPL10A,CMSS1,MOV10,RPL6,MRPL9,TRA2A,NGDN,RPS10,NKAP,SNRPA1,LYAR,SRSF10,DKC1,SRP14,KRR1,SRSF1,HP1BP3,MRPS18A,ZCCHC17,LARP4B,WWP1,PRKCA,HEXIM1,RPL26L1,H1-5,RBMS2,NPM3,RPS15,TRA2B,BRIX1,MRPL20,UTP23,FYTTD1,MECP2,ZCRB1,YPEL5,ELAVL2,RPS5,H1-1,MYC,RPF2,RPL7A,H2BC9,ZNF668,ZCCHC7,RPS3,FAU,FGFBP1,UBASH3B |
| 8.258e-03 | -4.80 | AI837181 (expressed sequence AI837181) | protein interactions | 107242 | 63 | 27 | 19454 | 5460 |
TFRC,CDK1,DDX39A,HNRNPK,PHB2,VDAC1,DDX5,PDIA6,PGK1,RUVBL2,PABPC1,DDX39B,NONO,PPIB,HNRNPAB,CALR,PDIA3,DHX15,PPIA,EIF4H,TAGLN2,RAN,EIF4A3,SRSF1,PHB1,SYNCRIP,ARF1 |
| 8.258e-03 | -4.80 | HSDL1 (hydroxysteroid dehydrogenase like 1) | protein interactions | 83693 | 63 | 27 | 19454 | 5460 |
RTN4,AKAP1,NMRAL1,EDA2R,LPAR2,PICK1,TSPAN15,RPA3,SLC31A1,HCST,MTCH2,TOMM22,PITPNA,CYB5B,CRELD1,HBB,PITPNB,STUM,CD63,ESR2,SCN3B,KDSR,TM4SF20,MDFI,TYROBP,SAYSD1,PPTC7 |
| 8.258e-03 | -4.80 | POLB (DNA polymerase beta) | protein interactions | 5423 | 63 | 27 | 19454 | 5460 |
STUB1,LIG3,PARP2,TOP1,SRPK2,CETN2,APEX1,HMGA1,CSK,TLE1,CRBN,TDP1,BRCA1,BRD3,EMX2,PCNA,EP300,EMC2,HUWE1,NUCKS1,SSRP1,TAF1D,PRKCA,RBPJ,RAD1,NUPR1,APTX |
| 8.258e-03 | -4.80 | CYB561 (cytochrome b561) | protein interactions | 1534 | 63 | 27 | 19454 | 5460 |
SLC38A7,OPRM1,CREB3,SYNJ2BP,TMEM179B,REEP6,TM4SF18,TMEM11,SLC19A3,CLDN9,GGT7,SSMEM1,CDIPT,EFNA5,ANKRD46,SEC22A,PLP2,EHHADH,GOSR2,BET1,TMEM14B,VAPB,LMNA,GPX4,ERG28,FKBP8,RNF5 |
| 8.258e-03 | -4.80 | SCNN1A (sodium channel epithelial 1 subunit alpha) | protein interactions | 6337 | 63 | 27 | 19454 | 5460 |
CST11,DERL1,HUWE1,USP8,TMEM106A,NCR3,HGS,SIGLECL1,SFTPC,GP9,WWP1,FUT1,TSG101,UBE2I,TSPAN18,CD1A,DNAJB9,HNRNPL,HECW1,SNX3,CSNK2A1,GGH,WWP2,USP2,STX1A,SDF2L1,TAFAZZIN |
| 8.281e-03 | -4.79 | regulation of circadian rhythm | biological process | GO:0042752 | 114 | 46 | 18204 | 5365 |
HDAC3,GHRL,ATG7,PPARG,CIPC,SOX14,PSPC1,PTGDS,SIN3A,PPP1CB,PML,FBXW11,CRY1,PPP1CC,EZH2,CHRNB2,GNA11,OPRL1,KCNA2,SIAH2,KLF10,CDK1,ADORA1,ADRB1,PIWIL2,KDM2A,FBXW7,CSF2,CCAR2,MAPK10,PROX1,BHLHE40,NONO,PPARA,FBXL3,NR2F6,THRAP3,RORB,NLGN1,UBE3A,ROCK2,TP53,USP2,CSNK1E,HNRNPD,GNAQ |
| 8.282e-03 | -4.79 | PES1 (pescadillo ribosomal biogenesis factor 1) | protein interactions | 23481 | 244 | 86 | 19454 | 5460 |
BUB3,RPL7L1,APEX1,ESR2,MAD2L2,SRPK2,LMBR1L,INPP5K,CCNF,ZNF330,TRIM23,RC3H2,LMNB1,TLR9,FTSJ3,NSA2,DNAJB6,RIT1,UBE2H,MYC,RPF2,RPL7A,CUL3,DNAJC8,NPM3,UFL1,FBXW7,LZTFL1,STAU1,RPL4,WDR55,BRIX1,CXXC1,AATF,RPL27,RPA3,SIRT7,RNF113A,RPA2,RPL27A,UBA52,BET1,CDK7,CAND1,TOP1,CGAS,RPL7,DKC1,DHX15,CEP19,RPL8,KRR1,PHB1,MRTO4,DDX23,WDR12,H2AC4,SNRNP70,DRG1,RPL23,PDIA3,IFI16,MOV10,WWP2,CSNK2A1,PPIL4,DDRGK1,KRAS,G3BP1,H3C1,TRIM26,NOC4L,GNL1,KLHL23,RPL31,RPS24,CDK8,EZH2,HDAC11,NUPR1,RAF1,TP53,SOX2,AURKAIP1,MAP1LC3B,KIF2A |
| 8.282e-03 | -4.79 | PPP2CB (protein phosphatase 2 catalytic subunit beta) | protein interactions | 5516 | 244 | 86 | 19454 | 5460 |
PPP2R2C,MLH3,PSMC1,SERTAD2,NMRAL1,HDAC5,CRY1,HSPA8,TTC1,STK26,IER2,TAB1,DYNLL1,CBX5,PSMB6,ESR2,OTUD6A,CCT2,PFDN2,PFDN6,PSMA4,HMGCS1,TTC33,KRAS,SSRP1,CTTNBP2,CCT8,MOB3C,TOP3B,MAX,RAF1,SUPT5H,PPP2R1A,CDK17,TCP1,SLMAP,CCT7,GSTA1,IGBP1,PPFIA3,RPLP1,WDR12,SKIC8,PDCD10,IFI16,PPP2R5A,HR,PFDN5,MARCHF5,ATG7,PRKCB,ACP5,SNAI2,CFTR,NDN,ADRM1,CTTNBP2NL,CDC20,SRC,TBCCD1,PSMC5,MOB4,PPP2R5E,INTS12,NIF3L1,STK24,STK11,FGFR1OP2,CAMK2G,TGFBR2,NOSIP,SIKE1,IK,PPP4C,TAB2,PPME1,PSMC3,TBC1D4,CCT5,MAP2K3,DDX39A,MYL12A,POLE3,DECR2,LCMT1,SMAD4 |
| 8.287e-03 | -4.79 | positive regulation of cellular component biogenesis | biological process | GO:0044089 | 515 | 177 | 18204 | 5365 |
IL1RAP,TAPT1,ZNF304,HRAS,PYCARD,LRRC24,S100A10,EMILIN1,POLDIP2,RALB,EPHA2,STUB1,CLU,SYK,RPS3,CNOT6L,TFRC,SLAIN2,LRRTM2,SLITRK2,TRIM32,ROCK2,SMAD3,CX3CL1,TNF,CDC42EP3,MIEN1,LRRN1,CCL19,ARF6,CLDN3,LRTM2,PIP4K2C,TPPP3,NLGN2,PRKCA,ADNP,CTTN,LRRC4B,TESK1,ASIC2,USP16,NUP62,SH3GLB1,TLR4,THY1,STX18,EPS8,CRBN,CCL11,SRC,CALY,DAG1,RAC2,VPS4A,NEK7,CLEC7A,P2RY12,ROCK1,IFNG,NLGN1,TP53,PIK3CA,SDC4,CD47,LPAR1,SDCBP,ACTR2,CLSTN3,NTRK2,FLRT2,CXCL13,AMIGO1,MAPRE1,CDKN1B,PIK3R1,NF2,ATAT1,CAPG,VEGFA,FAF1,MECP2,SLITRK1,GPM6A,TPBG,LGALS3,SMAD4,CCR7,TLR6,ISG15,TPPP,VPS4B,TGFB3,WNT7A,WASL,PTPN22,NCK1,RALA,OXTR,CCL24,BAK1,MAP1B,SNX18,CNOT2,DLG1,MSN,CNOT6,CBLN1,BECN1,FLRT3,SOX9,KIT,MET,CCL21,GHRL,CDC42EP2,LCP1,RAP1B,CLRN1,SUMO1,HGS,CHGA,PRKCE,DRG1,TIRAP,NRP1,CAND1,NR1H2,TSG101,NCKAP1,IL5,SLX1A,FLOT1,WDR45,CDK5R1,HSP90AA1,SYNDIG1,CSF2,PSRC1,MORC2,HAS3,LRRTM3,CDC42,SFRP1,SLITRK5,FERMT2,BAX,LDB2,FCHSD2,G3BP2,LRRTM1,G3BP1,CLDN1,FAM98A,CBLN2,RGCC,MYD88,TACR1,GPRASP3,CRB3,CAV3,MSTN,EFNA5,KCTD17,MNS1,SEPTIN7,CD36,CDC42EP4,SWAP70,WNT10B,ARPC2,MAVS,CAV1,TPPP2,GPR65,CHMP2A,MAD2L2 |
| 8.295e-03 | -4.79 | regeneration | biological process | GO:0031099 | 155 | 60 | 18204 | 5365 |
FKRP,RPS15,PLG,PRMT5,TMEM182,CDK1,KLK6,LARGE1,DAG1,CXCL12,LAMB2,WNT7A,PPP3CA,OMG,SOX2,UGT1A1,ELAVL4,SRSF1,GPX1,PCNA,MAP1B,IL6,BAK1,FGF10,CCN3,KPNA1,IL10,UCP2,F7,TNF,IGF1,CD81,NINJ1,PTN,IFRD1,CCNA2,CD9,VPS54,CLDN1,SELENON,CCND1,NREP,TNR,CTNNA1,RGN,RUNX1,TSPO,NEFL,GJA1,MSTN,LCP1,EZH2,TYMS,GUCD1,BCL9,CDKN1A,WNT10B,MTPN,JAK2,FOLR1 |
| 8.311e-03 | -4.79 | BCL2 (BCL2 apoptosis regulator) | protein interactions | 596 | 153 | 57 | 19454 | 5460 |
PML,PSEN2,ITM2B,SOD1,SQSTM1,RTN4,PMAIP1,BNIP3L,TOMM20,PPP1CB,GHITM,ABCB1,CRYAB,CDK1,ACACA,PRKCA,BAD,UBE2I,DYNLL1,VIRMA,MYC,MAT2A,PPP1CC,BAG3,RHEB,BFAR,BRCA1,BAX,HSP90AA1,VDAC1,KRAS,SMN1,FKBP8,PSEN1,CDK4,TP53,RAF1,DDX39A,PPARA,PPID,CAPN2,HRAS,XXYLT1,LDLR,NLRP1,CDK9,PPP2R5A,BAK1,SIVA1,TMBIM6,BECN1,IKBKB,PPP3CA,BCL2L1,PEX3,SPHK2,HNRNPD |
| 8.311e-03 | -4.79 | SOX6 (SRY-box transcription factor 6) | protein interactions | 55553 | 153 | 57 | 19454 | 5460 |
PHB1,TIMM8B,SSBP1,SUMO3,BRMS1L,CCAR2,SUMO2,HMG20A,MRPS23,TLE1,HMGA1,CTNNB1,PPIL4,SMCHD1,FOXP1,LSM14A,RING1,ASF1A,SATB1,ZNF609,G3BP1,FOXP4,FLOT1,POLDIP3,RPS13,MTA3,TIMM8A,ING1,SOX2,DDX39A,SSBP3,RPS11,ILF2,SOBP,ATXN1L,ZHX3,UBE2I,QSER1,ING2,IRF2BP1,PRRC2A,MORC4,HNF1B,LDB1,RPS17,CIRBP,IGF2BP1,HIRA,RADX,KDM1A,HDAC3,PIAS1,SUMO1,TIMM13,COX6C,CTBP1,IRF2BPL |
| 8.311e-03 | -4.79 | UPF2 (UPF2 regulator of nonsense mediated mRNA decay) | protein interactions | 26019 | 153 | 57 | 19454 | 5460 |
SNRNP70,CDK5RAP3,AGPAT1,HMGA1,CALR,E4F1,XPO1,MIF,SUMO3,NOB1,PAIP1,FZR1,ALYREF,SRSF1,RPL8,H2AZ1,TYMS,ACTR2,COMTD1,TOP3B,RAF1,EXOSC8,LGR4,RPS7,MAP1LC3B,THRAP3,DCP2,KRAS,ATP1B3,CASC3,RRP7A,EXOSC1,HS3ST3A1,MYC,PRPF31,LGALS3,LDHA,MAGOHB,VIRMA,ENO1,EIF4A3,CCNF,RMDN3,HBB,RPA2,STAU1,NOP53,PHB2,MRPL40,UFL1,RPS15,SAP18,UPF3B,RPA3,SMARCD3,PYM1,EXOSC4 |
| 8.311e-03 | -4.79 | UQ_con | pfam domains | PF00179 | 39 | 19 | 17795 | 5224 |
UBE2F,UBE2G2,UBE2V2,UBE2W,UBE2E2,UBE2A,UBE2B,KRAS,UBE2L3,UBE2M,UBE2S,UBE2I,UBE2N,UBE2V1,UBE2H,UBE2D1,UBE2E3,UBE2K,UBE2D3 |
| 8.317e-03 | -4.79 | JPH1 (junctophilin 1) | protein interactions | 56704 | 225 | 80 | 19454 | 5460 |
RAB2A,RSPH1,RAB11A,DNAJC5,LAMTOR1,LMNB1,RHOB,NTRK3,EPHA2,ATP1A1,COP1,PLP1,LMBR1L,RETREG3,RMDN3,SEC61B,RHOJ,VIRMA,ESR2,SEC63,ATP6AP2,BET1,EDDM3B,OTULINL,RND2,CDC42,SEC62,ST7,SSR1,CXCR4,RHOU,TEX264,SYVN1,RAB5A,RAB9A,DERL1,PXMP2,STX7,WDR55,DPP4,LAMP2,RAB5C,SLC25A46,ZCCHC10,LAMP3,RHOG,ESYT1,BRD3,STYK1,PTPN1,RAB35,GJA1,HSD17B11,RAC2,DNAJC1,ARF6,EIF2B5,RHOH,TNFSF18,LMAN1,STX6,TMPO,CAV1,CCDC47,CHRM3,DNAJC25,ARHGAP12,STIM1,RPN1,RAB4A,RND3,CYP2C9,TMT1A,NTRK2,CAMKV,KRAS,RAB3B,LEPROTL1,FKBP8,FLOT1 |
| 8.394e-03 | -4.78 | response to monosaccharide | biological process | GO:0034284 | 161 | 62 | 18204 | 5365 |
GCLC,RMI1,KCNJ11,PPP3CA,HNF1B,RAB11B,ZBED3,PPARA,AGER,ITGA2,LEP,PFKFB2,SELENOS,SMAD4,SELENOT,KCNB1,PIK3CA,ADIPOQ,TNF,ACVR1C,UCP2,SARM1,IL1A,SMAD3,RAF1,ICAM1,TWNK,GPAM,GLUL,IGF1R,SOD2,CLTRN,EIF2B3,GPX1,MIR15A,PCK2,PLCB1,XBP1,MIR320A,CDKN1B,SMAD2,SESN2,SLC29A1,CYP7A1,OPRK1,CCDC186,MIR221,MIR146A,NPTX1,EIF2B5,VAMP2,SIN3A,PAX6,EGR1,TXNIP,FKBP1B,PRKCB,MIR16-1,CMA1,MIRLET7G,TRA2B,EIF2B2 |
| 8.394e-03 | -4.78 | sphingolipid metabolic process | biological process | GO:0006665 | 161 | 62 | 18204 | 5365 |
PRKD3,CERS2,HACD2,PPT1,ST6GALNAC3,OSBP,ELOVL3,CERS6,GALC,SGMS1,SERINC1,FA2H,DEGS1,BAX,HEXA,LARGE1,CERK,PLA2G15,FUT1,ORMDL3,GAL3ST1,HACD4,ABCG2,SPTSSB,B3GALT1,ITGB8,SPHK2,ELOVL6,ELOVL7,B4GALT4,HACD1,CLN8,ST3GAL1,UGCG,NEU1,ELOVL1,HEXB,SMPD2,FUT9,B3GALT2,SPTSSA,ACER3,B4GALT3,TECR,ST8SIA5,HACD3,KIT,SGMS2,KDSR,HTRA2,ORMDL1,AGK,ST3GAL5,CYP4F22,B3GALNT1,B4GALT6,B3GALT4,ST3GAL2,TLCD3B,ST8SIA4,ELOVL4,VPS54 |
| 8.415e-03 | -4.78 | DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3) | protein interactions | 5611 | 203 | 73 | 19454 | 5460 |
DNAJC7,CAMSAP2,SMAD4,PPIB,TENM3,PDIA3,CALR,DPP4,EDEM1,CLEC18A,NDC80,LMAN1,HNRNPL,DNAJB9,DNAJC1,PRNP,CORO1C,ATP6V1A,PLD3,RPN1,SFTPC,B3GNT2,HEXA,PRDX4,SIAE,FKBP8,ROCK2,PCNA,ERO1A,SEPTIN7,IGF1R,EMC2,ERP29,PDIA6,NUDT5,SP1,DEDD,NTRK3,CALU,DNAJB6,SDF2L1,DNAJC10,GGH,HSPA14,ROCK1,SEC63,PYGM,B4GALT4,GANAB,SEC61B,CREB1,WNT10B,LMBR1L,EIF2AK2,FKBP10,HNRNPH3,MET,P3H1,LMNA,FGFR1,HSP90B1,TIRAP,CNPY3,TMEM231,FUT8,ARHGAP1,GRPEL1,HSPA5,EMC1,HSPA8,AKAP1,TMEM106B,WNT7A |
| 8.417e-03 | -4.78 | regulation of synaptic transmission, glutamatergic | biological process | GO:0051966 | 77 | 33 | 18204 | 5365 |
CNR1,DRD3,PSEN1,CACNG3,ATP1A2,RNF167,CCR2,HDAC6,GRM2,HOMER1,GRM1,CDK5,GRIK1,ADORA1,DKK1,NLGN2,HTR2A,TNR,OPHN1,MIR142,OXTR,MEF2C,DRD1,SLC38A2,UCN,NLGN1,GRM8,FRRS1L,DISC1,CCL2,TNF,STXBP1,ATAD1 |
| 8.417e-03 | -4.78 | glycolipid biosynthetic process | biological process | GO:0009247 | 77 | 33 | 18204 | 5365 |
GAL3ST1,ST3GAL5,ST8SIA5,CERK,PIGK,FUT1,LARGE1,B4GALT3,SLC30A5,PIGY,DPM2,GAL3ST4,ST8SIA4,ST3GAL4,B3GALT1,ST3GAL2,B4GALT6,B3GALT4,B3GALNT1,PIGC,B4GALT4,ST6GALNAC3,GPAA1,PIGW,PIGA,B3GALT2,FUT9,PGAP2,PGAP3,FA2H,PGAP4,ST3GAL1,UGCG |
| 8.421e-03 | -4.78 | establishment of blood-brain barrier | biological process | GO:0060856 | 12 | 8 | 18204 | 5365 |
VPS4B,CLDN3,CTNNB1,FZD4,WNT7A,FOXP3,BPGM,NDP |
| 8.421e-03 | -4.78 | protein folding in endoplasmic reticulum | biological process | GO:0034975 | 12 | 8 | 18204 | 5365 |
CALR,DNAJC10,HSPA5,DNAJC3,PDIA2,PDIA3,ERO1A,HSP90B1 |
| 8.421e-03 | -4.78 | phenol-containing compound catabolic process | biological process | GO:0019336 | 12 | 8 | 18204 | 5365 |
FAH,SULT1A3,COMT,DIO3,SLC6A3,DBH,PDE1B,MOXD1 |
| 8.421e-03 | -4.78 | response to interleukin-15 | biological process | GO:0070672 | 12 | 8 | 18204 | 5365 |
PLCB1,CD4,IL15RA,IL2RB,IL2RG,JAK1,STAT5A,IL15 |
| 8.421e-03 | -4.78 | SNARE complex assembly | biological process | GO:0035493 | 12 | 8 | 18204 | 5365 |
VAMP8,STXBP6,CLTRN,VAMP2,VAMP3,SNAP25,STXBP1,VAMP1 |
| 8.421e-03 | -4.78 | morphogenesis of an endothelium | biological process | GO:0003159 | 12 | 8 | 18204 | 5365 |
CTNNB1,CCM2,CXCR4,CSNK2B,MIR21,RBPJ,STARD13,RHOB |
| 8.421e-03 | -4.78 | endothelial tube morphogenesis | biological process | GO:0061154 | 12 | 8 | 18204 | 5365 |
CCM2,CXCR4,CTNNB1,RBPJ,RHOB,STARD13,CSNK2B,MIR21 |
| 8.421e-03 | -4.78 | negative regulation of collagen metabolic process | biological process | GO:0010713 | 12 | 8 | 18204 | 5365 |
MIR29A,IL6,EMILIN1,CYGB,CYP7A1,NPPC,MIR218-1,CST3 |
| 8.421e-03 | -4.78 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902043 | 12 | 8 | 18204 | 5365 |
STK4,STK3,FAF1,PMAIP1,ATF3,BMPR1B,SFRP1,PEA15 |
| 8.422e-03 | -4.78 | LTK (leukocyte receptor tyrosine kinase) | protein interactions | 4058 | 150 | 56 | 19454 | 5460 |
TECR,GAB1,DLST,EIF2S2,MSN,MACROH2A1,BLVRA,MYO6,EPHA2,NAA50,PIK3R3,PYCR2,PTPN11,GORASP2,UBE2D3,FTSJ1,STAU1,PIK3R2,SAP18,UNC45A,DDX39B,SNRPA,ZNF326,TOMM22,NOTCH2,CDC42,CNP,EIF2S1,RAB1B,SUMO2,STT3A,MRPS9,PTPN1,SRP14,AIP,WDR6,UBE2N,DUSP6,CDCA3,SHC1,CBL,GRSF1,KARS1,PIK3R1,SSRP1,SFXN1,ABCE1,DHX9,NDUFS3,NHERF1,HGS,RAF1,TOP3B,ERRFI1,SUPT5H,NUDCD3 |
| 8.422e-03 | -4.78 | HABP4 (hyaluronan binding protein 4) | protein interactions | 22927 | 150 | 56 | 19454 | 5460 |
DKC1,PRKCQ,SURF6,SYNCRIP,MRPS9,SRSF1,MRTO4,MRPS26,PDCD10,ANKRD50,TMA16,MOV10,FRA10AC1,DHX16,TOLLIP,MORC2,TOPORS,GTPBP1,SMNDC1,LBH,KIF2A,H2AJ,RAF1,TP53,TCEAL7,SPCS1,CHMP5,RPS20,UBE2I,ENO2,POP7,EZH1,PEA15,MRPS25,ANAPC15,NONO,MYC,NHP2,MRPS7,PSENEN,MRPL17,FXR2,NOP53,PRKCB,CCDC86,EMG1,JADE1,UPF3B,UTP15,TFB1M,PRKCA,CSNK1A1,APOBEC3C,MRPS34,CDK7,EHHADH |
| 8.449e-03 | -4.77 | regulation of immune effector process | biological process | GO:0002697 | 390 | 137 | 18204 | 5365 |
CD46,LILRB4,CD81,IFNA2,MIR21,SOCS5,IL20RB,TNFRSF1B,TLR9,SH2D1A,IL4,MYD88,CD28,CD36,SEMA7A,B2M,CD80,IL23A,EXOSC3,FERRY3,HMCES,IFNB1,TYROBP,RIGI,TICAM1,LGALS3,MAD2L2,RC3H2,MAVS,SERPINB9,FGL2,PHB2,MICB,CD40LG,LEP,TLR4,CD1A,NECTIN2,RAC2,IL18,MIF,SASH3,JUNB,LILRB1,HSPA8,ANGPT1,FOXP3,IL12A,HSPD1,BCL10,HTR2A,CLEC7A,RSAD2,IL21,IL6,IL13,CD86,IL17F,IFNG,DDX1,IL12B,CD1E,ICAM1,FGR,TLR3,IL2,CCR2,IRF4,CCL19,VAMP3,ADGRE2,LITAF,CYRIB,DNAJB9,KLRD1,CLEC12B,CD59,XBP1,TNFSF13,CD1B,NDFIP1,KIT,CD1C,NLRP3,TRAF6,LACC1,LTA,FCGR1A,CGAS,TLR7,STXBP1,TNFRSF14,IL5,PLA2G5,ACP5,STX7,SPHK2,BST2,KLK3,STAT6,FCGR2B,NCR3,CD226,DUSP10,MZB1,BATF,STAP1,PYCARD,AGER,MBL2,HMGB1,SYK,CD1D,IL1B,TGFB3,CD40,TMBIM6,HFE,BCL6,VAMP8,SHLD1,TRAF2,CX3CR1,KMT5B,KLRC2,TRIM6,TFRC,PHB1,VAMP7,KLK5,TNF,EP300,XCL1,IL10,DUSP22,FCN2,TGFB2 |
| 8.459e-03 | -4.77 | PBRM1 (polybromo 1) | protein interactions | 55193 | 241 | 85 | 19454 | 5460 |
ZMYND11,BCL7C,HDAC6,IRF4,HMGA1,PRDX1,IFI16,PDIA3,RPL10A,LHX2,BRD3,KPNA1,POU5F1,H2AC4,BRD9,SNX17,EED,TYMS,SDHB,H2AZ1,KLF9,ZBTB2,OR8B8,SUMO2,TOP1,RPS16,ELF1,SOX9,SOX2,H2AX,PTS,RANBP1,RAF1,RNF8,SMARCB1,NDUFS3,EZH2,UBE3A,RPL3,PAX6,SSRP1,MSH6,KPNA2,H3C1,AR,SMARCE1,IRF1,HNF1B,MYC,YPEL5,PTEN,MACROH2A1,CALML5,FGFBP1,ELK3,ZNF330,ESR2,VIRMA,APEX1,CDC20,UMPS,ACTB,HACD2,LMO3,KLF12,H1-5,ACTL6A,SYK,RPLP0,ELF5,E2F6,PAX9,KLF3,PPARG,NUP50,DDIT3,SYVN1,ACER3,FOS,SIRT7,SMARCD3,SS18,COIL,ZDHHC17,NUCKS1 |
| 8.469e-03 | -4.77 | retrograde transport, endosome to Golgi | biological process | GO:0042147 | 94 | 39 | 18204 | 5365 |
TMEM87A,RAB9A,VPS26B,LMAN1,RAB9B,SNX12,SNX1,TBC1D17,STX6,SNX3,TRAPPC10,PHETA2,RAB6A,TBC1D5,RHOBTB3,VAMP3,VPS54,VPS26A,TMED9,RGP1,STX16,BET1L,TRIM27,SNX2,SNX5,STX5,EHD3,PREPL,STX10,PLEKHJ1,SURF4,RAB29,VTI1B,TBC1D10C,YKT6,RAB6B,RNF126,SLC66A2,GOSR1 |
| 8.469e-03 | -4.77 | negative regulation of autophagy | biological process | GO:0010507 | 94 | 39 | 18204 | 5365 |
PHF23,WDR6,CPTP,RRAGA,PIK3CA,EP300,RRAGB,IL10,TP53,TAB2,TMEM39A,SEC22B,EIF4E,CTSA,LYPLA1,NUPR1,USP30,DAP,LEPR,MET,PTPN22,TSPO,KLHL22,MCL1,ADRA1A,STK38L,AKT1,MIRLET7B,HDAC6,RNF5,SNRNP70,SCFD1,POLDIP2,BECN1,TRIM27,LEP,RNF41,MTM1,FEZ1 |
| 8.473e-03 | -4.77 | DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7) | protein interactions | 7266 | 399 | 134 | 19454 | 5460 |
RAN,DLST,LMBR1L,PAPSS2,IFT172,ANAPC2,FBXO22,BTG3,CHCHD3,POLR2B,SFN,CUL3,CDC123,MYC,APOBEC3B,DSN1,MLF2,MAP3K21,YWHAZ,FBXW11,LAMTOR1,FAS,SERPINH1,DNAJB6,HSP90AA1,DNAJC3,TTC1,AKAP1,PMAIP1,NMRAL1,HSPA8,STAU1,RADX,EEF1G,MCMBP,RNF5,UFL1,DET1,PPARG,CNDP2,PHB1,WDR6,ATXN10,OCRL,FAM98A,PGR,LRWD1,HSP90AB1,CACYBP,PEG10,EGLN3,NDC80,MARCHF5,DDRGK1,IQSEC1,SMAD9,HNRNPD,HAX1,HSPD1,BAG2,DNAJB4,ETFA,WDR19,ETFB,PLS3,TUBB4B,NUDT19,MOB3C,STUB1,CCNF,TRIM27,TXN,DYRK1A,SMURF1,NR1I2,PYCR2,RSPH1,TRIM32,NAA50,PSMB2,ST13,AR,DNAJC5,NCAPG2,USP14,TXNIP,HERC4,UBE2H,SMAD2,NCDN,BAP1,RPA3,MIS12,PIK3R2,HSPA5,ARHGAP1,SEC22B,SAMM50,RPA2,DCTN4,UBE2M,SCLT1,HEXIM1,PWP2,PREP,PRNP,FZR1,G6PD,FUNDC2,LMAN1,DNAJB2,GAPDH,ECD,DNAJC7,SMG8,AKAP8L,PSME1,EHD4,NAE1,RAB1A,ABCE1,DYNC1I1,PTGES3,PSEN1,FBXO25,MTCH2,TP53,KBTBD4,RRM1,MAP1LC3B,DISC1,SURF4,RAD1,APEH |
| 8.483e-03 | -4.77 | endolysosome | cellular component | GO:0036019 | 29 | 15 | 19108 | 5553 |
TLR3,AP2A1,TASL,LDLR,TLR7,SLC48A1,CTSK,AP2S1,ATG16L1,AP2M1,PCSK9,TLR9,RNF167,CTSB,TLR8 |
| 8.499e-03 | -4.77 | FH (fumarate hydratase) | protein interactions | 2271 | 178 | 65 | 19454 | 5460 |
CRIP1,LAMP2,YWHAG,AGR2,YWHAB,AIFM1,SSBP1,H2AZ1,UBE2N,TOP1,DBT,DHX15,MMP20,CMPK1,HEXA,E2F4,H2AX,TNPO2,PGM1,UBR7,GNPNAT1,EZH2,PIR,GDI2,GNPDA2,SOD2,CSTPP1,TRIP4,HAPSTR1,KRAS,XPNPEP1,LDHB,HMOX2,COX16,GLOD4,H2AZ2,YWHAZ,PNPO,QNG1,ENO1,CAB39,GNPDA1,MSN,LDHA,COPE,TENT5C,RPGRIP1L,SUCLG2,ADPRM,PAFAH1B1,RPA2,COX6C,ACAA2,MAP2K1,HEXB,BAP1,SIRT7,HSPA8,PDSS2,PGK1,SAT1,NSFL1C,OXCT1,GRPEL1,PYGB |
| 8.499e-03 | -4.77 | RUSF1 (RUS family member 1) | protein interactions | 64755 | 178 | 65 | 19454 | 5460 |
RNF5,SLC25A51,CLDND1,TMX2,BMPR1A,LRP10,VIPR1,RAB9A,SDCBP,LMNA,FGFR1,GPR35,GP9,SLC35E3,GINM1,ADIPOR1,PDCD1LG2,EHHADH,NPY2R,SEC62,OTULINL,GLRA2,NRSN2,NDFIP1,APLNR,UBB,TNPO3,PRRC2A,SYNGR1,EDNRA,RAB9B,RETREG3,STX10,UBE2I,SPCS3,FCER1G,FAM219A,CREB3,SCN3B,ZCCHC12,ARL6IP6,RPN1,BMPR2,AQP3,UGCG,SYNGR3,DHX38,TMT1B,WBP11,ALG11,IFNGR1,ADCK1,PRNP,RAMP3,TMEM237,TMEM248,LAPTM4A,SSMEM1,HSD17B11,ZDHHC15,FITM2,ICAM2,SELENOS,XPO1,MZT2B |
| 8.506e-03 | -4.77 | FoxO signaling pathway | KEGG pathways | hsa04068 | 132 | 59 | 7161 | 2463 |
RAF1,GRM1,IGF1R,STK11,CDKN2D,SMAD4,EP300,HRAS,GADD45A,CSNK1E,BCL6,TGFB2,SMAD2,PRKAB1,CDKN1B,STK4,IL6,IL10,FBXO25,HOMER1,SETD7,CCNB1,TGFBR2,AKT3,AGAP2,G6PC3,TNFSF10,MAP2K1,GABARAPL2,GADD45G,GADD45B,CCND1,FBXO32,MAPK10,S1PR4,CREBBP,MDM2,IKBKB,FASLG,SOD2,SMAD3,AKT1,PIK3R2,PTEN,KRAS,PIK3R1,TGFB3,HOMER3,PIK3CA,GABARAPL1,SOS2,PRKAG1,IGF1,PIK3R3,GABARAP,PCK2,CDKN1A,RAG1,AKT2 |
| 8.512e-03 | -4.77 | CEPT1 (choline/ethanolamine phosphotransferase 1) | protein interactions | 10390 | 66 | 28 | 19454 | 5460 |
UBE2H,OAZ1,PEX3,TOMM40,MARCHF5,MYC,ELK1,EGLN3,SEC61B,KRT8,ZNF330,CCNF,TMEM14B,SPG21,OTULINL,YIPF5,SOX2,CDC42,TP53,PGRMC1,CCDC47,IMMP2L,PSMC1,AKAP1,RAB9A,NMRAL1,EXD2,TMEM263 |
| 8.512e-03 | -4.77 | PDE4B (phosphodiesterase 4B) | protein interactions | 5142 | 66 | 28 | 19454 | 5460 |
NONO,CFL2,XPO1,MOV10,CALR,YWHAB,OAT,RPL24,ALB,RPS20,ENO1,PPIA,RPL35,LYAR,ACTN4,PAFAH1B1,RPSA,IFRD1,ARCN1,CAPZA2,HBB,DISC1,LCP1,PDIA6,HSPD1,G3BP2,RPS4X,SSR3 |
| 8.512e-03 | -4.77 | ANAPC10 (anaphase promoting complex subunit 10) | protein interactions | 10393 | 66 | 28 | 19454 | 5460 |
ANAPC16,KRAS,ANAPC11,MDC1,NEK2,PPP2R1A,ANAPC13,UTP15,SMAD3,TNFRSF1B,PTEN,ANAPC2,HNRNPL,FZR1,CDC20,APEX1,ESR2,CDC16,CDC26,PYCARD,CCNB1,ANAPC15,XPO1,SMPD2,CDC23,ANAPC4,SMAD2,NLRP3 |
| 8.512e-03 | -4.77 | ING2 (inhibitor of growth family member 2) | protein interactions | 3622 | 66 | 28 | 19454 | 5460 |
RBBP7,TGIF2LX,TGIF2,PCNA,EP300,SMARCB1,HBP1,SAP30L,KLF3,SMAD1,ELF1,SAP30,ACTL6A,TP53,ZNF704,SMURF1,KLF9,RBBP4,BRMS1L,PRMT5,GATAD1,COPS2,SIN3A,ELK3,SMAD2,AR,BRMS1,HNF1B |
| 8.512e-03 | -4.77 | TBX3 (T-box transcription factor 3) | protein interactions | 6926 | 66 | 28 | 19454 | 5460 |
PFDN5,PDIA3,CTNNB1,NONO,AR,EIF4A3,UFSP1,ATP5F1B,PLEKHF2,TMPO,CA8,SOX2,KLF3,LMNA,CDK8,MYL6,SLC25A3,NUFIP2,PML,XRCC5,DHX9,HSPA8,EWSR1,HDAC5,TOLLIP,HNRNPK,HDAC3,RPS27A |
| 8.512e-03 | -4.77 | PAEP (progestagen associated endometrial protein) | protein interactions | 5047 | 66 | 28 | 19454 | 5460 |
SLC25A12,STK3,LRIF1,UBB,BMP1,SLC25A4,MIOS,GTF2F2,OLFM2,MGME1,SMAD3,GGCX,RPL23,STK4,NKIRAS1,KLHL22,SAV1,IFI16,PROS1,HSPA5,IGSF21,SLC25A23,BANF1,GRAMD2B,TMX2,EEF1A1,UBL4A,ERVFRD-1 |
| 8.512e-03 | -4.77 | LYPLAL1 (lysophospholipase like 1) | protein interactions | 127018 | 66 | 28 | 19454 | 5460 |
NQO1,TST,BTF3,GRSF1,FAH,RAMP3,SH3BGRL,TAX1BP1,GATD3,DSTN,CCDC90B,CCNF,SSBP1,ANXA7,MTRES1,SCLT1,PDHA1,IDH2,CTDSP1,CDK7,MAP1LC3B,HINT1,GFM1,COX8A,HINT2,PEBP1,HSPD1,PTRHD1 |
| 8.512e-03 | -4.77 | DCTN6 (dynactin subunit 6) | protein interactions | 10671 | 66 | 28 | 19454 | 5460 |
ORC6,HSPB2,DCTN3,ACTR1B,KRAS,CAPZA1,TIMM10,AKR7A2,ERRFI1,RPSA,ACTR1A,SPMIP6,CDK1,DCTN4,CAPZA2,UBE2M,CCL19,CXCL14,SPPL3,DYNC1I2,UQCRH,RSPH1,RAB11A,MED22,CCL4L1,BMERB1,MAPRE1,RIT1 |
| 8.512e-03 | -4.77 | AGPAT4 (1-acylglycerol-3-phosphate O-acyltransferase 4) | protein interactions | 56895 | 66 | 28 | 19454 | 5460 |
CCNF,RETREG3,HSD17B11,CYB5A,MGST3,REEP4,RAMP3,SLC7A8,SCN3B,TSPAN10,FCGR2A,MFSD14B,JAGN1,TMX2,CXCR4,TSPAN15,NMRAL1,VIPR1,TSPAN17,SLC7A1,GRPR,LPAR1,TSPAN5,LEPROTL1,RIGI,SEC62,TMEM31,TMEM14B |
| 8.512e-03 | -4.77 | SULT1A1 (sulfotransferase family 1A member 1) | protein interactions | 6817 | 66 | 28 | 19454 | 5460 |
STUB1,SULT1A3,SRXN1,TMOD3,AUH,UBE2H,RHOG,TTC1,DVL2,BAP1,PPM1G,RPA3,SNCG,AHCYL1,PTGES3,UBE2A,COIL,STAP1,UCHL3,TOM1L2,CDC42,SUMO1,RAF1,RND3,ZRANB2,UBE2B,STMN2,RPA2 |
| 8.512e-03 | -4.77 | ZNF384 (zinc finger protein 384) | protein interactions | 171017 | 66 | 28 | 19454 | 5460 |
CUL3,MYC,COP1,RPS9,TRIM27,ZNF330,OPTN,RPL19,APEX1,SNRNP40,CEBPE,RPS10,SOX2,MED9,TP53,TOP3B,RBPJ,RPA2,LMNA,NUP50,SQSTM1,COX8A,ZYX,RPA3,SSRP1,COIL,ASF1A,UBE2K |
| 8.531e-03 | -4.76 | GLE1 (GLE1 RNA export mediator) | protein interactions | 2733 | 147 | 55 | 19454 | 5460 |
PRPF19,MOV10,IFI16,NXT2,FKBP4,NXT1,AIP,SRP14,FUBP3,CACYBP,SURF6,NUP35,CDC5L,RPS10,LYAR,NUP153,NUDCD3,H1-3,YTHDF2,LLPH,GLE1,NDUFS3,ZC3H7A,ZC3H11A,RPL3,PABPC1,SRSF4,NUP107,KRAS,THRAP3,TTC4,NUP42,MYC,RPL7A,H1-1,FYTTD1,FGFBP1,PRKRA,SEC61B,LMBR1L,RPS3,S100A6,RAN,RPL19,FGF13,NUP62,H1-5,ZC3H14,RPLP0,IER2,TTC1,BRIX1,UTP23,FXR2,NPM3 |
| 8.542e-03 | -4.76 | Mit_carrier | interpro domains | IPR002067 | 34 | 17 | 18521 | 5414 |
SLC25A17,SLC25A10,SLC25A21,SLC25A14,SLC25A44,SLC25A1,SLC25A4,SLC25A24,SLC25A31,SLC25A32,SLC25A5,UCP2,SLC25A42,SLC25A39,SLC25A12,SLC25A23,SLC25A45 |
| 8.576e-03 | -4.76 | PON2 (paraoxonase 2) | protein interactions | 5445 | 200 | 72 | 19454 | 5460 |
ST3GAL5,HNRNPL,MARCHF4,ANKRD46,NUP35,CD1A,COMT,ITGA6,ATP6V1A,RNF128,BPNT2,POR,ST3GAL4,TNFSF13,TMEM30A,ST6GALNAC3,LRFN3,KRAS,CAMK2G,HS2ST1,SAR1B,RDH11,UST,PRELP,RNF167,CHST10,ART5,RUVBL2,SFTPC,NDUFS3,MOXD1,KLRC2,CA14,POMT2,FURIN,RAP1A,NETO2,B3GNT2,CCDC47,HTR2A,CLEC2B,MAP1LC3B,B4GALT3,BMP1,ATP6AP2,VIRMA,MAD2L2,UQCRC2,ST8SIA5,CCNF,AMIGO1,B4GALT1,CMA1,TAFAZZIN,KLK5,CUL3,ADRB2,RER1,ST8SIA4,EMC1,HSPA5,TMEM106B,DUSP9,DNAJC3,GRM2,STOM,PTP4A2,CYC1,TMEM219,HYAL2,UQCRC1,TMEM106A |
| 8.578e-03 | -4.76 | Thrombin signalling through proteinase activated receptors (PARs) | REACTOME pathways | R-HSA-456926 | 32 | 17 | 10285 | 3229 |
GNG2,GNG12,GNGT2,GNB3,SRC,GNA11,GNG3,GNG13,GNB1,GNB4,GNA14,GNG7,GNG10,GNG11,GNAQ,GNG5,F2 |
| 8.593e-03 | -4.76 | multi-multicellular organism process | biological process | GO:0044706 | 200 | 75 | 18204 | 5365 |
IL1B,SPP1,RGS2,TGFB3,ERRFI1,CLDN4,AKT1,OVGP1,PRL,JUNB,PITHD1,LEP,MAGED2,ITGA2,UPRT,POLR1B,STOX2,PTGFR,PARP2,TCF23,IDO1,ACSL4,SLC2A1,TAC1,STC1,OXTR,PRDX3,PNOC,PLA2G4B,MMP9,RPL29,EPYC,VMP1,VDR,GJB2,CRHBP,FKBP4,RLN2,NDP,PGR,TPPP3,SLC38A3,TACR1,DDR1,EMP2,KLF1,GHRL,THBD,CD38,CNR1,UMPS,CYP1A1,AR,PTN,SOD1,MIR21,CAPN2,PTHLH,CTSB,B4GALT1,CYP27B1,SLC6A4,EPO,FOS,PPP3R2,CRHR1,HEXB,DEDD,LDOC1,SMCP,SLC38A2,SLC38A1,UCN,KPNA6,BMPR2 |
| 8.639e-03 | -4.75 | response to axon injury | biological process | GO:0048678 | 55 | 25 | 18204 | 5365 |
SOD1,LAMB2,DAG1,CTNNA1,NREP,TNR,NDP,CDK1,MORN4,FLRT3,NEFL,TSPO,SOD2,MIR34A,P2RY12,BAX,SLC1A1,MAP1B,NPPC,FOLR1,TYROBP,JAK2,EPO,KCNB1,SARM1 |
| 8.643e-03 | -4.75 | PPP1R9B (protein phosphatase 1 regulatory subunit 9B) | protein interactions | 84687 | 175 | 64 | 19454 | 5460 |
CTTN,CCNF,CDIPT,ACTB,CTSB,NMI,ESR2,CUL3,MYC,USP14,PPP1CC,BRCA1,CDKL2,MAPRE1,NRP1,ARHGEF6,SNX33,NMRAL1,STAU1,PPP1R2,CMAS,RPS14,ATG16L1,CDK7,GABRA1,PPP1CB,CDC42,CSNK1A1L,MED23,TMOD1,ACSL4,RPL8,RB1,KRT8,USP46,CACNB3,ARHGAP25,HNRNPL,CYTH4,CDK9,KXD1,DPP4,SHC1,TIAM1,TCOF1,ADRA1A,ZYX,SOS2,TRIM37,COPS4,PAK6,RIGI,TOP3B,TRMT1L,SOX2,ACTN4,CCM2,CAPZA2,PDHA1,TFRC,NUPR1,MRPL51,CSTPP1,CDK5R1 |
| 8.652e-03 | -4.75 | SIVA1 (SIVA1 apoptosis inducing factor) | protein interactions | 10572 | 49 | 22 | 19454 | 5460 |
SSBP3,TRAF2,DDX39A,TP53,PXMP2,CAMK2G,PCNA,LPAR2,RHOU,BCL2L1,BEX3,UBE2D1,TXNIP,NTAQ1,EGLN3,MDM2,APEX1,TCAP,FOXP3,CD4,FAIM,S1PR4 |
| 8.652e-03 | -4.75 | TRIM72 (tripartite motif containing 72) | protein interactions | 493829 | 49 | 22 | 19454 | 5460 |
G3BP2,NMI,EGR1,UBE2N,BCKDK,UBE2I,COMMD2,ZNF655,PGK1,CCDC22,UBE2D1,SMAD4,MED21,UBE2H,PPP3CA,TP53,COMMD8,ASRGL1,TRIM32,PIK3R1,COMMD3,CAV3 |
| 8.652e-03 | -4.75 | RELL2 (RELT like 2) | protein interactions | 285613 | 49 | 22 | 19454 | 5460 |
SLC1A1,CDIPT,PLP1,MPDU1,TSPO2,ANKRD46,RHEB,SYNJ2BP,MGST2,HSPA14,RELL1,MLF1,SLC35A1,HADHA,NSG1,ACVR1B,ZNF32,SEC22B,FUT8,OXSR1,FAM3C,TFRC |
| 8.652e-03 | -4.75 | CRIP1 (cysteine rich protein 1) | protein interactions | 1396 | 49 | 22 | 19454 | 5460 |
PGK1,SOD1,YKT6,UFM1,NME1,PPP2R5E,ACAT1,DSTN,CBFB,STUB1,PPIA,MIF,SNX3,LGALS3,TAGLN2,CAPG,CFL2,CD81,CFL1,HNRNPA1,COTL1,AK2 |
| 8.652e-03 | -4.75 | TSPO (translocator protein) | protein interactions | 706 | 49 | 22 | 19454 | 5460 |
AQP3,ATP5PO,EZH2,KCNF1,TMEM14B,ADORA3,ATP5PB,RAF1,MAP1LC3B,VDAC1,ARF4,ICAM3,FCER1G,NCR3LG1,CISD1,AGPAT1,ATP5MG,ATP5F1A,GPX1,PYGM,VDAC2,AMIGO1 |
| 8.652e-03 | -4.75 | LYST (lysosomal trafficking regulator) | protein interactions | 1130 | 49 | 22 | 19454 | 5460 |
PCBP4,CSNK2B,CNTROB,PPIA,VIRMA,MYC,SFN,CSNK2A1,YWHAG,YWHAH,YWHAZ,ANAPC4,YWHAB,NCDN,HNRNPH2,MRPL17,VTA1,TOP3B,KIF1C,ESS2,SAP30,HGS |
| 8.696e-03 | -4.74 | fibroblast proliferation | biological process | GO:0048144 | 39 | 19 | 18204 | 5365 |
KCNJ8,CD248,FGF10,CKS1B,GPX1,CKS2,ECD,NUPR1,HRAS,RRN3,COL3A1,CAV1,PRDX1,PTGES3,ING5,GNG2,TP53,CDK1,CDKN1A |
| 8.696e-03 | -4.74 | glial cell activation | biological process | GO:0061900 | 39 | 19 | 18204 | 5365 |
IL13,PSEN1,IFNGR1,AGER,KCNJ8,TLR6,CX3CR1,AIF1,IL1B,IFNG,TLR2,MIR181C,TLR3,CX3CL1,TNF,TYROBP,JAK2,CLU,TLR9 |
| 8.707e-03 | -4.74 | regulation of oxidoreductase activity | biological process | GO:0051341 | 66 | 29 | 18204 | 5365 |
CAV3,POR,NUS1,MT3,TERT,HP,NFKB1,VDR,NDUFA4,IFNG,FGF23,CYP27B1,SPHK2,IL1A,TNF,COX17,NOSIP,ATP2B4,LEP,MIR378A,MIR21,HDAC6,PHB2,FXN,MIR130B,IL1B,AKT1,GFI1,NOS1AP |
| 8.718e-03 | -4.74 | SMAD MH1 domain | gene3d domains | 3.90.520.10 | 8 | 6 | 14470 | 4137 |
SMAD9,SMAD2,SMAD1,SMAD4,SMAD3,SMAD5 |
| 8.722e-03 | -4.74 | mRNA transport | biological process | GO:0051028 | 123 | 49 | 18204 | 5365 |
XPO1,THOC2,HNRNPA1,NUP107,MX2,ENY2,THOC6,POLDIP3,MAGOH,G3BP2,PEG10,CETN2,NCBP2,NXT2,MAGOHB,DDX39B,SEC13,THOC1,EIF4E,NUP37,EIF4A3,DHX9,SRSF1,CHTOP,NXT1,NUP42,HNRNPA2B1,SRSF7,ZC3H11A,PARP11,THOC3,SMG5,TNKS,NUP62,DDX39A,IGF2BP1,NUP35,UPF3B,CETN3,FXR2,ALKBH5,FYTTD1,ALYREF,GLE1,BICD2,CASC3,NUP153,RBM15B,NUP50 |
| 8.731e-03 | -4.74 | endoplasmic reticulum-Golgi intermediate compartment membrane | cellular component | GO:0033116 | 81 | 34 | 19108 | 5553 |
YIF1A,COPZ2,RAB1B,TMED7,BET1,VMP1,TAPBP,LAMP5,TMED9,GALNT1,TMED1,STX17,FOLR1,GOSR2,SEC22B,SURF4,TMED5,TMED3,CTSC,CD59,MGAT1,RAB2A,GRIA1,YKT6,STX5,SPPL3,KDELR1,SERPINA1,TMEM199,CNIH1,LMAN1,CALR,AZIN2,CLN8 |
| 8.734e-03 | -4.74 | ANKRD39 (ankyrin repeat domain 39) | protein interactions | 51239 | 69 | 29 | 19454 | 5460 |
COPS7A,PTPN11,CUL2,CUL3,TBCE,COPS5,ATG7,FBXO7,BAG3,BLVRA,ATG3,LANCL2,HERC4,SRSF1,COPS2,COPS7B,AASDHPPT,UBA3,RRM1,MTMR6,CKS1B,GNB1L,NAE1,FBXW4,THNSL1,TRIM63,PITHD1,ADO,COPS4 |
| 8.734e-03 | -4.74 | ATP5MF-PTCD1 (ATP5MF-PTCD1 readthrough) | protein interactions | 100526740 | 69 | 29 | 19454 | 5460 |
FASTKD5,KRAS,COX8A,GFM1,HINT2,EXD2,RPA3,NGRN,MTRES1,GFM2,PDHA1,RPA2,METTL15,MAP1LC3B,CDC42,MRPL11,RHOH,DYNC1I2,GATD3,TACO1,SSBP1,MRPS26,RHOG,TUFM,PMPCA,GRSF1,MOV10,AUH,MTRF1 |
| 8.734e-03 | -4.74 | RPS4Y2 (ribosomal protein S4 Y-linked 2) | protein interactions | 140032 | 69 | 29 | 19454 | 5460 |
CHMP4C,HECTD1,HEXIM1,RPLP0,RPSA,CSNK1E,ZNF428,CFTR,RPL4,DGCR8,FTL,MEPCE,SNIP1,RPL3,H1-1,RPS2,RPL7A,EMILIN1,ZNF668,LYAR,RPS10,RPS16,SURF6,RPL19,KRR1,SRP14,DNASE1L1,PRKRA,FGFBP1 |
| 8.742e-03 | -4.74 | WASF2 (WASP family member 2) | protein interactions | 10163 | 141 | 53 | 19454 | 5460 |
ESR2,VIRMA,NCKAP1,ACTB,PSMC5,NTRK3,BICD2,RHOB,PSMD1,RAB11A,WASF3,ZDHHC17,POLA2,STX7,SLC31A1,CYFIP2,SIRT7,BAP1,DDX46,CSNK1G3,VIPAS39,FGFR1,CDC42,PSMC4,ATG16L1,HSBP1,CEP19,KCTD10,ZNF511,ARF6,RAC2,HOMER3,RAB35,WDR6,HRAS,YWHAB,NCK1,YWHAH,ATG7,YWHAG,WWP2,RIGI,CCAR1,WASL,KRAS,EPHA4,IGF1R,APEH,PSMC3,ACTR2,ARPC3,MECR,ARHGAP12 |
| 8.745e-03 | -4.74 | EMC complex | cellular component | GO:0072546 | 10 | 7 | 19108 | 5553 |
EMC10,EMC1,EMC4,EMC2,EMC6,EMC9,EMC8 |
| 8.745e-03 | -4.74 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | cellular component | GO:0000276 | 10 | 7 | 19108 | 5553 |
ATP5PD,ATP5MG,ATP5MC1,ATP5PF,ATP5MC3,ATP5PB,ATP5PO |
| 8.749e-03 | -4.74 | PTCH1 (patched 1) | protein interactions | 5727 | 270 | 94 | 19454 | 5460 |
HYAL2,PSMC4,CHPF2,WWP1,STOM,CSNK1A1L,CDK1,MTDH,HSPA5,ST8SIA4,CNNM4,CHPF,CCNB1,CREB3,NPTX1,PIP4K2C,B4GALT1,PSMC5,PSMA6,VIRMA,SMURF1,MGAT1,LBR,POMT2,PSMC3,VAC14,GALNT2,RDH11,B4GALT7,KPNA2,L1CAM,ELOC,PPIL4,LRFN3,ST6GALNAC3,USP15,AGPAT1,AKAP8L,EXT1,ITGA6,CAV1,TRAPPC6B,SEMA3C,ANKRD46,MYL6,CSNK1A1,APPBP2,TMEM160,SKP1,CMAS,ITGAV,ATG101,PSMD1,CUL3,PSMA4,LDHB,CUL2,RAB11A,LSM14B,PDF,CIRBP,RAN,PRRC2A,ABHD12,B4GALT3,PSMD6,TOP3B,NETO2,ZRANB2,MOXD1,RPN1,LSM14A,PSMD12,MYORG,PSMA1,QPCTL,PPIB,FIG4,WWP2,MARCHF5,CD200R1,PRPF19,PSMD3,CLPX,ST3GAL4,RB1CC1,BPNT2,ADGRG1,PHB1,OS9,PXYLP1,PPIA,COCH,PCSK9 |
| 8.752e-03 | -4.74 | ATPase regulator activity | molecular function | GO:0060590 | 49 | 23 | 18094 | 5411 |
CCAR2,DNAJB4,PLN,BAG2,DNAJC10,NKRF,AHSA1,DNAJB6,ATP1B1,ATP1B3,DNAJC7,ATP5IF1,GTF2H4,GRPEL1,TOR1AIP2,DNAJC2,HSCB,DNAJB2,DNAJC24,GRPEL2,BAG3,DNAJC19,DNAJC1 |
| 8.752e-03 | -4.74 | molecular sequestering activity | molecular function | GO:0140313 | 49 | 23 | 18094 | 5411 |
XAF1,SEC14L1,FTH1,SDCBP,SQSTM1,CDKN1A,CALR,TSSC4,SFN,INSIG2,TRIM15,PRDX4,YWHAG,TMSB4X,IMPACT,CTNND1,CAV1,NOSIP,USP38,SESN2,WDR44,NFKBIA,YWHAZ |
| 8.761e-03 | -4.74 | GJA5 (gap junction protein alpha 5) | protein interactions | 2702 | 38 | 18 | 19454 | 5460 |
GJA1,MFSD5,LHFPL2,EMP3,RPRM,HRAS,LEPROTL1,RIMS3,TMEM107,MAP1LC3B,TMBIM6,SLC41A1,BLCAP,TP53,PGAP2,GJB2,SLC35F1,FCER1G |
| 8.761e-03 | -4.74 | TIMM21 (translocase of inner mitochondrial membrane 21) | protein interactions | 29090 | 38 | 18 | 19454 | 5460 |
TUBA1A,MTMR12,EPHA2,HSPB1,RPA2,SPOP,ABCE1,EMG1,TERT,CCNF,MAIP1,LMBR1L,NDUFA4,DUSP6,EGLN3,MAD2L2,IMMP2L,EYA3 |
| 8.761e-03 | -4.74 | SEC61A2 (SEC61 translocon subunit alpha 2) | protein interactions | 55176 | 38 | 18 | 19454 | 5460 |
CUL3,PTPN5,CSK,CCDC47,RAF1,CFTR,AQP3,SYP,EZH2,EXD2,BMPR1A,SLC1A1,LRRN4CL,SEC61B,VIPR1,APEX1,SEC63,TOMM6 |
| 8.761e-03 | -4.74 | VIPAS39 (VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog) | protein interactions | 63894 | 38 | 18 | 19454 | 5460 |
MATN4,STX7,STX6,LYG2,RABIF,ARL10,FIS1,YWHAB,RPA2,VPS33A,TFRC,LAMTOR1,RAB4A,CCDC22,ATG9A,VPS39,CUL3,RAB11A |
| 8.761e-03 | -4.74 | DONSON (DNA replication fork stabilization factor DONSON) | protein interactions | 29980 | 38 | 18 | 19454 | 5460 |
ANKRD50,RPL24,ARMCX3,GINS4,CDK1,MCM4,AATF,MCM6,GINS3,MED17,KRAS,TRA2B,CTNNBL1,PSMA3,BST2,PCNA,PELO,VPS72 |
| 8.761e-03 | -4.74 | QDPR (quinoid dihydropteridine reductase) | protein interactions | 5860 | 38 | 18 | 19454 | 5460 |
CUL3,SPR,DDX39A,SOX2,COPS5,GLO1,ELF5,MAPRE1,CCNF,SOD1,PREP,HSD17B8,HSD17B10,ARFIP1,CAND1,KRAS,HSPE1,PAGR1 |
| 8.761e-03 | -4.74 | TAPT1 (transmembrane anterior posterior transformation 1) | protein interactions | 202018 | 38 | 18 | 19454 | 5460 |
STUM,DERL1,RAB9A,SEC61B,DNAJC1,ZBTB2,SEC63,SMURF1,CSK,PTAR1,ST7,SMAD1,SEC62,DNAJC25,OTULINL,RIC3,RPN1,SEMA7A |
| 8.761e-03 | -4.74 | JAKMIP1 (janus kinase and microtubule interacting protein 1) | protein interactions | 152789 | 38 | 18 | 19454 | 5460 |
MAPRE1,YWHAB,ZDHHC15,YWHAZ,TUBB4B,YWHAH,YWHAG,USP2,MRPL11,CHRM3,ENKD1,YES1,GABBR1,PSMB1,JAK1,JAKMIP1,SCNM1,DCLRE1C |
| 8.761e-03 | -4.74 | GNPDA2 (glucosamine-6-phosphate deaminase 2) | protein interactions | 132789 | 38 | 18 | 19454 | 5460 |
LTBR,SOD1,PEBP1,SNX12,TRIM27,MTAP,GNPDA1,MAGOHB,UMPS,DSN1,ERRFI1,CABCOCO1,MARCHF5,SHMT1,NTAQ1,PIR,PPID,AKR1A1 |
| 8.761e-03 | -4.74 | LRRIQ1 (leucine rich repeats and IQ motif containing 1) | protein interactions | 84125 | 38 | 18 | 19454 | 5460 |
COP1,EPHA2,ACVR1,BMPR2,GTF2IRD1,LGR4,IFNGR1,NOTCH2,EMILIN1,NDFIP1,STX10,JAK1,LRP10,BAP1,BMPR1A,DVL2,VAMP3,RPA3 |
| 8.761e-03 | -4.74 | SYCE1L (synaptonemal complex central element protein 1 like) | protein interactions | 100130958 | 38 | 18 | 19454 | 5460 |
SCHIP1,TNNI1,MED10,KCNIP2,ZNF526,CCHCR1,TRAPPC13,CENPP,CSK,PFDN5,NTAQ1,NOL4,LCA5L,OIP5,SRSF10,CYTH4,SLC7A8,BOLL |
| 8.761e-03 | -4.74 | CDKN1C (cyclin dependent kinase inhibitor 1C) | protein interactions | 1028 | 38 | 18 | 19454 | 5460 |
FBXO22,CDK9,CCND3,MYBL2,PCNA,RB1,CDK6,CDK1,NR4A2,AKT1,CCND1,TP53,CCNB1,CDK4,NEUROD6,COPS5,CCNA2,CDK7 |
| 8.761e-03 | -4.74 | CBR3 (carbonyl reductase 3) | protein interactions | 874 | 38 | 18 | 19454 | 5460 |
USP3,SDCBP,BICD2,NDUFS3,UPK1A,CCR1,RAB35,EWSR1,ZBTB18,ABCE1,LDLR,RPS10,DCUN1D1,S100A10,FBXO22,TUBB,IMMP2L,RABIF |
| 8.761e-03 | -4.74 | KCNE4 (potassium voltage-gated channel subfamily E regulatory subunit 4) | protein interactions | 23704 | 38 | 18 | 19454 | 5460 |
TMEM126A,CNNM4,RHOBTB3,ALG11,KCNIP2,TSNAX,KCNA3,FAM8A1,PRKCA,CAMLG,RAB29,LRP10,DDR1,KCND2,BMPR1A,SYVN1,ACVR1B,SRC |
| 8.761e-03 | -4.74 | S100A1 (S100 calcium binding protein A1) | protein interactions | 6271 | 38 | 18 | 19454 | 5460 |
PYGM,PLEKHF2,DES,CAPZA1,MDM2,CACYBP,S100B,GJA1,FKBP4,PPID,AGER,NIF3L1,IFNB1,BEX3,PLN,TP53,BAG3,PGM1 |
| 8.788e-03 | -4.73 | CCDC33 (coiled-coil domain containing 33) | protein interactions | 80125 | 172 | 63 | 19454 | 5460 |
SMARCB1,HGS,STK16,NEFL,PNMA2,TRAF2,SPG21,CDCA7L,STX11,AP1M1,HNRNPF,HNRNPK,CRYBA4,TRIM37,CRYBA2,KLHL15,EMC2,PLSCR1,CDC23,NAB2,ZNF688,PID1,MDFI,KXD1,CENPP,TMCC2,TOR1B,SMAD3,GYS1,MFAP1,FRS3,CCNH,LMO3,ING5,FAM161A,LDOC1,KDM1A,FXR2,DVL2,ARHGEF6,EXOC8,CCHCR1,ARMC7,GCC1,TRIM23,ATOSB,PRPF31,CCDC85B,LMO2,HNRNPC,PIK3R3,CHCHD3,BCCIP,MAGOHB,KCTD9,YES1,HEXIM2,PRMT5,UBASH3B,PNMA1,CINP,SCNM1,ZNF330 |
| 8.788e-03 | -4.73 | ERC1 (ELKS/RAB6-interacting/CAST family member 1) | protein interactions | 23085 | 172 | 63 | 19454 | 5460 |
RAB6B,VPS33A,DUSP1,ING1,CDK20,EWSR1,CYP2C9,AKT2,YWHAB,POU5F1,RASSF8,MED4,AGR2,IKBKB,STK4,YWHAH,YWHAG,INSYN1,NDC80,VPS26A,MAPK4,MACROD1,SNX2,DYNC1I2,GFOD1,KRT8,SCLT1,TMOD1,RAB6A,CDK7,SEC62,NUP62,ATG16L1,FTL,STAU1,KDM1A,FLCN,BAP1,DVL2,MAPRE1,BRCA1,RPS6KA4,BICD2,YWHAZ,MYO6,CRLF3,DNAJC5,RACGAP1,CUL3,PYCARD,MYC,SRPK2,DES,VIRMA,APEX1,DYRK1A,SMURF1,ANAPC2,PHF21A,GSK3A,DLST,NFKBIA,LMBR1L |
| 8.798e-03 | -4.73 | Transducin (heterotrimeric G protein), gamma chain | gene3d domains | 4.10.260.10 | 17 | 10 | 14470 | 4137 |
GNG5,GNG11,GNGT2,GNG7,GNG2,GNG3,RGS6,GNG10,GNG12,GNG13 |
| 8.812e-03 | -4.73 | TIR | pfam domains | PF01582 | 19 | 11 | 17795 | 5224 |
TLR7,TLR9,IL1RAP,TLR8,TLR1,TLR3,TLR6,TLR10,TLR4,TLR5,TLR2 |
| 8.824e-03 | -4.73 | RAD51 (RAD51 recombinase) | protein interactions | 5888 | 235 | 83 | 19454 | 5460 |
CCND1,SUMO1,TPT1,MND1,CDC42,TIMM13,RPA2,ACACA,HECTD1,TRIM36,PML,NBN,RPA3,UGDH,SQSTM1,HSPA8,NMRAL1,TRA2B,UCHL3,KDM1A,ZDHHC17,PIAS1,MORF4L1,HNRNPC,MCM3,SNRPB,BRCA1,LMNB1,MCM8,RIT1,PRSS1,PTTG1,HSP90AA1,CDC73,SP1,MIDEAS,TUBA1B,UBE2I,MCPH1,PTEN,PHF21A,CSNK2B,CAB39,SNRPD1,UMPS,BCCIP,TP53,E2F4,TOP3B,PPP2R1A,TUBA1A,H2AX,TOPORS,HNRNPA2B1,RPL31,TFPT,PCNA,KHDC1,SEM1,RNF115,KRAS,EIF2D,MDC1,MSH6,DUSP21,RPS4X,RNF20,RAB5C,CDH11,CSNK2A1,XPO1,CSTA,TUBG1,TOPBP1,CDH13,FABP5,BRD9,IGBP1,MAP1LC3A,SUMO2,SNRPD3,NAT2,HMG20A |
| 8.843e-03 | -4.73 | PTCD1 (pentatricopeptide repeat domain 1) | protein interactions | 26024 | 138 | 52 | 19454 | 5460 |
MRPL13,ESR2,MRM2,HNRNPC,MYC,RPL26,MRPS25,FBXW11,SYP,MCAT,H1-1,AMACR,NGRN,HSCB,UTP23,MRPS7,PABPC5,CFTR,RBMS2,MRPS18A,QRSL1,TFIP11,FAHD1,PRR3,KCTD10,MRPL50,PAIP1,RBM42,MALSU1,RPL6,MOV10,TRA2A,HNRNPA1,RPS2,RBM3,SDHC,HSPD1,MRPL52,SRSF7,MRPS18B,RASL10B,NUP42,SRSF4,MRPS17,TP53,SOX2,AURKAIP1,DUSP1,APOBEC3D,MRPL51,GFM2,ILF2 |
| 8.864e-03 | -4.73 | immunoglobulin production | biological process | GO:0002377 | 47 | 22 | 18204 | 5365 |
FOXP3,CTNNBL1,POLL,BCL6,HSPD1,GAPT,MAD2L2,HMCES,POLB,SAMHD1,CD40LG,BATF,EXOSC3,NBN,CCR6,TRAF3IP2,SWAP70,SHLD1,RNF8,STAT6,MSH6,NHEJ1 |
| 8.864e-03 | -4.73 | negative regulation of lipid transport | biological process | GO:0032369 | 47 | 22 | 18204 | 5365 |
MIR130B,PTPN11,MIR145,NFKB1,FIS1,CRY1,MIR34A,MIR33B,MIR9-1,TSPO,ITGAV,AKT2,MIR17,MIR301B,MIR206,AKT1,MIR148A,MIR185,NR1H2,MIR144,PCSK9,APOC2 |
| 8.890e-03 | -4.72 | MOK (MOK protein kinase) | protein interactions | 5891 | 30 | 15 | 19454 | 5460 |
S100A8,CLPB,FTL,ACTB,ECHDC1,STAT1,HUWE1,JUN,H1-3,CCNB1,AKT1,NAA50,CMPK1,MYC,PNPO |
| 8.890e-03 | -4.72 | LCMT1 (leucine carboxyl methyltransferase 1) | protein interactions | 51451 | 30 | 15 | 19454 | 5460 |
LDLR,CCNF,RPA3,PPP2CB,EIF4H,FXR2,TAB1,CFTR,RRM1,CMPK1,CUL3,EIF1AX,PPP4C,BRCA1,NECAP1 |
| 8.890e-03 | -4.72 | FABP3 (fatty acid binding protein 3) | protein interactions | 2170 | 30 | 15 | 19454 | 5460 |
PTRHD1,SOD1,DSTN,HINT1,TAGLN2,SH3BGRL,VPS28,NUP62,GSTK1,LYPLAL1,AK2,IDH2,TST,TNNI3K,FKBP1A |
| 8.890e-03 | -4.72 | PABIR1 (PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1) | protein interactions | 116224 | 30 | 15 | 19454 | 5460 |
YWHAZ,YWHAB,PPP3CA,SFN,ISCA2,POLR3GL,XPO1,YWHAG,PPP2R1A,YWHAH,PPP2R2C,PPP2CB,KLHL15,LDLR,FHL3 |
| 8.890e-03 | -4.72 | TGIF2 (TGFB induced factor homeobox 2) | protein interactions | 60436 | 30 | 15 | 19454 | 5460 |
PAPOLA,TP53,FBXO7,PSMD1,BRMS1,SAP30,RBBP8,SAP30L,SIN3A,SMAD3,ING2,TGIF2,KRAS,FBXW7,BRMS1L |
| 8.890e-03 | -4.72 | ZNF420 (zinc finger protein 420) | protein interactions | 147923 | 30 | 15 | 19454 | 5460 |
CEP19,STK3,MDM2,MEF2A,TNFRSF1B,ZNF330,UBE2I,PRKRA,CBX3,HAX1,TP53,SAV1,CYP4V2,CDC42,H2AX |
| 8.890e-03 | -4.72 | AP4S1 (adaptor related protein complex 4 subunit sigma 1) | protein interactions | 11154 | 30 | 15 | 19454 | 5460 |
TIMM29,TOP3B,ATG9A,CDC73,FGFR1,DISC1,MECP2,APPBP2,HAPSTR1,RPL10,GALNT2,TMPO,GTF2I,HSCB,KRAS |
| 8.890e-03 | -4.72 | PECAM1 (platelet and endothelial cell adhesion molecule 1) | protein interactions | 5175 | 30 | 15 | 19454 | 5460 |
JUP,PPP2R1A,CTNNB1,RBM12,PIK3R1,CSK,CD38,PTPN11,ADD2,SRC,FZR1,PRKCE,YES1,SYVN1,PIK3CG |
| 8.890e-03 | -4.72 | CSF3R (colony stimulating factor 3 receptor) | protein interactions | 1441 | 30 | 15 | 19454 | 5460 |
PTPN11,HMGA1,SYK,WSB1,FTH1,CISH,CDKN1A,SOCS3,SHC1,SPHK2,JAK1,FBXW7,FZR1,JAK2,DMPK |
| 8.890e-03 | -4.72 | Fbl (fibrillarin) | protein interactions | 14113 | 30 | 15 | 19454 | 5460 |
BECN1,SMNDC1,RPLP0,IFI16,WDR77,HMGA1,NOP58,YTHDF1,COIL,HELLS,CCNF,ABCF1,CLK1,PRMT5,JADE1 |
| 8.890e-03 | -4.72 | SENP8 (SUMO peptidase family member, NEDD8 specific) | protein interactions | 123228 | 30 | 15 | 19454 | 5460 |
CRBN,USP15,RIT1,TRMT5,UBE2M,CUL2,RPS14,AKIP1,NEDD8,CHN2,KRAS,SPPL3,SMURF1,COPS2,PCNA |
| 8.890e-03 | -4.72 | BFAR (bifunctional apoptosis regulator) | protein interactions | 51283 | 30 | 15 | 19454 | 5460 |
UBE2W,TMBIM6,UBE2D1,IFT57,ACACA,BCL2L1,TMED1,UBE2N,ATP5IF1,TYMS,UBE2K,NDUFS2,UBE2D3,VAMP7,PHYKPL |
| 8.915e-03 | -4.72 | oxidoreductase activity, acting on CH-OH group of donors | molecular function | GO:0016614 | 133 | 53 | 18094 | 5411 |
AKR1B1,CYP27A1,HSD17B6,DHRS3,DHRS11,LDHAL6B,HADH,HSD17B8,KDSR,GFUS,GPD2,AKR1C2,SDR16C5,CTBP1,DHRS1,IDH1,RDH12,ADH1B,HSD17B3,KCNAB1,AKR1E2,CHDH,ADH1A,IDH2,IDH3B,LDHB,EHHADH,HSD17B1,HSD17B11,HSD17B10,LDHA,SPR,AKR1C1,NSDHL,RDH10,RDH11,HADHA,AKR1A1,DHRS7B,IDH3A,CBR3,AKR7A2,CBR4,G6PD,DHRS7,MDH1,SDR42E1,DHRS4L1,HSD11B1,SORD,DHRS4,UGDH,CRYL1 |
| 8.923e-03 | -4.72 | Resolution of Abasic Sites (AP sites) | REACTOME pathways | R-HSA-73933 | 37 | 19 | 10285 | 3229 |
RFC3,POLE4,RFC5,POLD4,SMUG1,RFC2,RPA3,RPA2,MPG,PARP2,RFC4,POLD2,LIG3,POLB,OGG1,PCNA,APEX1,FEN1,POLE3 |
| 8.923e-03 | -4.72 | Base Excision Repair | REACTOME pathways | R-HSA-73884 | 37 | 19 | 10285 | 3229 |
FEN1,POLE3,APEX1,PCNA,OGG1,POLB,LIG3,POLD2,RFC4,PARP2,MPG,RPA2,RPA3,RFC2,SMUG1,POLD4,RFC5,POLE4,RFC3 |
| 8.924e-03 | -4.72 | gangliocytoma | COSMIC cancer mutations | gangliocytoma | 6 | 5 | 16828 | 4835 |
IDH1,PTEN,GNA11,GNAQ,TERT |
| 8.924e-03 | -4.72 | skin-upper_leg-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-upper_leg-other-seborrhoeic_keratosis | 6 | 5 | 16828 | 4835 |
PIK3CA,HRAS,PTEN,AKT1,PTPN11 |
| 8.924e-03 | -4.72 | skin-lower_back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-lower_back-other-seborrhoeic_keratosis | 6 | 5 | 16828 | 4835 |
HRAS,PIK3CA,PTPN11,PTEN,AKT1 |
| 8.924e-03 | -4.72 | astroblastoma | COSMIC cancer mutations | astroblastoma | 6 | 5 | 16828 | 4835 |
IDH2,PTPN11,IDH1,GNA11,GNAQ |
| 8.924e-03 | -4.72 | bone-femur-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-femur-chondrosarcoma-dedifferentiated | 6 | 5 | 16828 | 4835 |
IDH2,IDH1,TP53,HRAS,RB1 |
| 8.924e-03 | -4.72 | phalanx | COSMIC cancer mutations | phalanx | 6 | 5 | 16828 | 4835 |
KIT,CDH11,IDH1,AKT1,EWSR1 |
| 8.924e-03 | -4.72 | lateral_ventricle | COSMIC cancer mutations | lateral_ventricle | 6 | 5 | 16828 | 4835 |
IDH2,IDH1,SMARCB1,PTEN,KRAS |
| 8.924e-03 | -4.72 | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligoastrocytoma_Grade_III | 6 | 5 | 16828 | 4835 |
TP53,IDH2,PTEN,CDKN2C,IDH1 |
| 8.924e-03 | -4.72 | skin-flank-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-flank-other-seborrhoeic_keratosis | 6 | 5 | 16828 | 4835 |
HRAS,PIK3CA,PTEN,AKT1,PTPN11 |
| 8.924e-03 | -4.72 | gliomatosis_cerebri | COSMIC cancer mutations | gliomatosis_cerebri | 6 | 5 | 16828 | 4835 |
TP53,TERT,IDH1,PTEN,IDH2 |
| 8.924e-03 | -4.72 | ulna | COSMIC cancer mutations | ulna | 6 | 5 | 16828 | 4835 |
KIT,IDH2,CDH11,IDH1,EWSR1 |
| 8.924e-03 | -4.72 | skin-face-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-face-other-seborrhoeic_keratosis | 6 | 5 | 16828 | 4835 |
TERT,PIK3CA,HRAS,PTPN11,AKT1 |
| 8.924e-03 | -4.72 | central_nervous_system-parietal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-parietal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | 6 | 5 | 16828 | 4835 |
CTNNB1,TP53,IDH1,SMARCB1,IDH2 |
| 8.924e-03 | -4.72 | rhabdoid | COSMIC cancer mutations | rhabdoid | 6 | 5 | 16828 | 4835 |
IDH1,AKT1,NF2,IDH2,KIT |
| 8.924e-03 | -4.72 | central_nervous_system-brain-glioma-gliomatosis_cerebri | COSMIC cancer mutations | central_nervous_system-brain-glioma-gliomatosis_cerebri | 6 | 5 | 16828 | 4835 |
IDH1,PTEN,IDH2,TERT,TP53 |
| 8.924e-03 | -4.72 | central_nervous_system-temporal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | 6 | 5 | 16828 | 4835 |
IDH2,IDH1,SMARCB1,TP53,CTNNB1 |
| 8.924e-03 | -4.72 | central_nervous_system-frontal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-frontal_lobe-primitive_neuroectodermal_tumour-medulloblastoma | 6 | 5 | 16828 | 4835 |
IDH2,SMARCB1,IDH1,TP53,CTNNB1 |
| 8.924e-03 | -4.72 | skin-abdomen-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-abdomen-other-seborrhoeic_keratosis | 6 | 5 | 16828 | 4835 |
HRAS,PIK3CA,PTPN11,AKT1,PTEN |
| 8.924e-03 | -4.72 | skin-back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-back-other-seborrhoeic_keratosis | 6 | 5 | 16828 | 4835 |
PTEN,AKT1,PTPN11,HRAS,PIK3CA |
| 8.927e-03 | -4.72 | CHRAC1 (chromatin accessibility complex subunit 1) | protein interactions | 54108 | 72 | 30 | 19454 | 5460 |
MECP2,TRAPPC2L,HMGA1,SMARCA5,PTPN11,CUTA,RAB1B,FZR1,TOP1,POLE3,ESR2,HSP90AB1,H2AZ1,EED,MTAP,DCK,ADSS2,NME1,TRAPPC13,B3GNT2,RBBP7,ARL5B,NUCKS1,SSRP1,HSPA5,XRCC5,SLC35G2,INO80C,SLC39A7,IGF1R |
| 8.927e-03 | -4.72 | SLC25A19 (solute carrier family 25 member 19) | protein interactions | 60386 | 72 | 30 | 19454 | 5460 |
VIPR1,RPA3,MAIP1,RETREG2,IMMP2L,TNFSF8,HUWE1,NPTN,KRAS,OTULINL,CLEC2B,MGARP,RAF1,GEMIN7,RPA2,PTPN22,STARD3NL,SLC1A1,CCNF,DUSP6,APLNR,RAMP3,APEX1,FMOD,MOV10,ICAM2,RIT1,UBE2H,SYP,TRIM23 |
| 8.927e-03 | -4.72 | Dctn3 (dynactin 3) | protein interactions | 53598 | 72 | 30 | 19454 | 5460 |
DAPK3,ILVBL,ACTA2,MRPS9,GTF2F1,SEC61A1,PRSS1,RBM7,APOBEC3B,PRDX1,CCNQ,FXR2,CTSC,CAPZA1,PACSIN3,DCTN6,ACTR1B,DCTN3,CAPZA2,ARPC3,DCTN4,NFKBIL1,AP2S1,KLHL12,ZC3H14,RPSA,USP6NL,SNAP29,TPD52,ACTR1A |
| 8.941e-03 | -4.72 | TRAPPC2 (trafficking protein particle complex subunit 2) | protein interactions | 6399 | 135 | 51 | 19454 | 5460 |
PRMT2,CRYAB,TRAPPC6A,NICN1,KLC2,SLC39A9,RAP2A,ARPC2,NME4,PAPOLA,RAB2A,SLC30A5,TRAPPC14,YWHAZ,IGF2BP1,ZBTB38,ENO1,PTEN,ZNF655,B4GALT1,B4GALT3,MBL2,PYGM,DAPK1,UBB,SNAPC5,RAF1,ACTR2,EZH2,TUBB4B,TRAPPC3L,TRAPPC13,TRAPPC1,RAB1A,UQCC2,IGF1R,ZBED1,YWHAH,YWHAG,TRAPPC2L,CLIC2,YWHAB,LSM3,TRAPPC4,TRAPPC10,TRAPPC3,EED,CAND1,RAB1B,OPRL1,TRAPPC6B |
| 8.954e-03 | -4.72 | skin-mucosal-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-mucosal-malignant_melanoma-superficial_spreading | 8 | 6 | 16828 | 4835 |
GNAQ,PIK3CA,GNA11,KIT,HRAS,KRAS |
| 8.954e-03 | -4.72 | endometrium-carcinoma-mixed_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_cell_carcinoma | 8 | 6 | 16828 | 4835 |
TP53,CTNNB1,KRAS,PPP2R1A,PIK3CA,PTEN |
| 8.954e-03 | -4.72 | endocervical_adenocarcinoma | COSMIC cancer mutations | endocervical_adenocarcinoma | 8 | 6 | 16828 | 4835 |
PTEN,STK11,TERT,PIK3CA,KRAS,TP53 |
| 8.954e-03 | -4.72 | skin-vulva-malignant_melanoma-mucosal_lentiginous | COSMIC cancer mutations | skin-vulva-malignant_melanoma-mucosal_lentiginous | 8 | 6 | 16828 | 4835 |
PIK3CA,KRAS,GNAQ,KIT,GNA11,HRAS |
| 8.954e-03 | -4.72 | meninges-melanocytic_neoplasm | COSMIC cancer mutations | meninges-melanocytic_neoplasm | 8 | 6 | 16828 | 4835 |
GNAQ,TERT,KRAS,GNA11,HRAS,KIT |
| 8.954e-03 | -4.72 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-marginal_zone_lymphoma | 8 | 6 | 16828 | 4835 |
MYD88,NOTCH2,JAK2,TNFAIP3,HRAS,KRAS |
| 8.954e-03 | -4.72 | melanocytic_neoplasm | COSMIC cancer mutations | melanocytic_neoplasm | 8 | 6 | 16828 | 4835 |
GNA11,KIT,HRAS,KRAS,GNAQ,TERT |
| 8.954e-03 | -4.72 | ganglioneuroblastoma | COSMIC cancer mutations | ganglioneuroblastoma | 8 | 6 | 16828 | 4835 |
TERT,TP53,KIT,CTNNB1,IDH2,IDH1 |
| 8.954e-03 | -4.72 | frontotemporal | COSMIC cancer mutations | frontotemporal | 8 | 6 | 16828 | 4835 |
CTNNB1,TP53,CDKN2C,IDH1,IDH2,PTEN |
| 8.954e-03 | -4.72 | skin-vulva-malignant_melanoma-nodular | COSMIC cancer mutations | skin-vulva-malignant_melanoma-nodular | 8 | 6 | 16828 | 4835 |
GNAQ,PIK3CA,KIT,GNA11,HRAS,KRAS |
| 8.954e-03 | -4.72 | central_neurocytoma | COSMIC cancer mutations | central_neurocytoma | 8 | 6 | 16828 | 4835 |
TERT,TP53,PTEN,AKT1,IDH1,IDH2 |
| 8.954e-03 | -4.72 | skin-vulva-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-vulva-malignant_melanoma-superficial_spreading | 8 | 6 | 16828 | 4835 |
KRAS,HRAS,KIT,GNA11,GNAQ,PIK3CA |
| 8.954e-03 | -4.72 | skin-mucosal-malignant_melanoma-desmoplastic | COSMIC cancer mutations | skin-mucosal-malignant_melanoma-desmoplastic | 8 | 6 | 16828 | 4835 |
KIT,GNA11,HRAS,KRAS,PIK3CA,GNAQ |
| 8.954e-03 | -4.72 | skin-acral-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-acral-malignant_melanoma-acral_lentiginous | 8 | 6 | 16828 | 4835 |
GNAQ,KIT,GNA11,PIK3CA,MAP2K1,PTEN |
| 8.954e-03 | -4.72 | endometrioid_adenocarcinoma | COSMIC cancer mutations | endometrioid_adenocarcinoma | 8 | 6 | 16828 | 4835 |
STK11,PIK3CA,PTEN,HRAS,KRAS,TP53 |
| 8.954e-03 | -4.72 | skin-chronically_sun_exposed_site-malignant_melanoma | COSMIC cancer mutations | skin-chronically_sun_exposed_site-malignant_melanoma | 8 | 6 | 16828 | 4835 |
PIK3CA,MAP2K1,GNAQ,HRAS,GNA11,KIT |
| 8.954e-03 | -4.72 | cervix-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-small_cell_carcinoma | 8 | 6 | 16828 | 4835 |
TP53,RB1,HRAS,KRAS,SF3B1,PIK3CA |
| 8.954e-03 | -4.72 | cervix-carcinoma-endocervical_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endocervical_adenocarcinoma | 8 | 6 | 16828 | 4835 |
PTEN,TP53,PIK3CA,TERT,KRAS,STK11 |
| 8.954e-03 | -4.72 | mixed_cell_carcinoma | COSMIC cancer mutations | mixed_cell_carcinoma | 8 | 6 | 16828 | 4835 |
TP53,PIK3CA,CTNNB1,KRAS,PPP2R1A,PTEN |
| 8.954e-03 | -4.72 | chronically_sun_exposed_site | COSMIC cancer mutations | chronically_sun_exposed_site | 8 | 6 | 16828 | 4835 |
KIT,HRAS,GNA11,MAP2K1,PIK3CA,GNAQ |
| 8.954e-03 | -4.72 | central_nervous_system-brain-other-central_neurocytoma | COSMIC cancer mutations | central_nervous_system-brain-other-central_neurocytoma | 8 | 6 | 16828 | 4835 |
PTEN,TERT,AKT1,IDH1,IDH2,TP53 |
| 8.954e-03 | -4.72 | gastrointestinal_tract_(site_indeterminate)-carcinoma | COSMIC cancer mutations | gastrointestinal_tract_(site_indeterminate)-carcinoma | 8 | 6 | 16828 | 4835 |
JAK2,FBXW7,MET,KRAS,PIK3CA,TP53 |
| 8.954e-03 | -4.72 | regulation of T cell mediated immunity | biological process | GO:0002709 | 100 | 41 | 18204 | 5365 |
CYRIB,CD1A,AGER,NECTIN2,KLRD1,IFNA2,LILRB4,CD81,MICB,FCGR2B,CCR2,HSPD1,NLRP3,FOXP3,IL12A,HFE,TRAF6,IL4,CD1C,HSPA8,CD1B,LILRB1,IL1B,CD1D,HMGB1,TNFRSF1B,SASH3,IL18,IL20RB,IL23A,CD80,IL6,RSAD2,B2M,TRAF2,CD1E,STX7,XCL1,DUSP22,IL12B,IFNB1 |
| 8.968e-03 | -4.71 | nuclear export | biological process | GO:0051168 | 129 | 51 | 18204 | 5365 |
THOC3,ZC3H11A,RPS15,HNRNPA2B1,NUP42,NXT1,CHTOP,CTDSPL2,EIF4A3,AHCYL1,EIF4E,THOC1,DDX39B,MAGOHB,PHAX,NXT2,NCBP2,MAGOH,POLDIP3,THOC6,ENY2,NUP107,NOP9,CALR,HNRNPA1,THOC2,CHP1,XPO1,SFN,UBE2I,RBM15B,DESI1,CASC3,NUP153,EGR2,GLE1,SMURF1,CCHCR1,CDKN1B,RAN,ALYREF,FYTTD1,ALKBH5,ABCE1,STRADB,CSE1L,XPOT,DDX39A,XPO5,NUP62,SMG5 |
| 9.011e-03 | -4.71 | MCRS1 (microspherule protein 1) | protein interactions | 10445 | 232 | 82 | 19454 | 5460 |
CSRNP1,SSMEM1,CNTROB,BRMS1L,SUV39H1,XPO1,INSYN1,ZCCHC10,INO80E,DPY30,KXD1,BRD3,MED4,NAB2,INO80C,RUVBL2,BHLHE40,TFPT,RERE,CDCA7L,TRIM37,RUVBL1,ZNF609,KRAS,DYNC1I1,TULP3,ELF1,WBP11,EGR2,SP4,SNAPC5,BHLHA9,GPBP1L1,PNMA2,TNNI1,PTEN,PRMT5,RPL37A,CSNK2B,RETREG3,KIAA1958,ELK3,TRIM44,ESR2,CAVIN2,BRMS1,AR,CEP70,TBC1D1,DRAP1,CCDC85B,ZCCHC12,KANSL3,H2BC9,MYC,COPS7A,RIT1,CCHCR1,TADA3,LSM6,BRCA1,GCC1,TERT,NKAPD1,HCFC2,JAKMIP1,UPF3B,BAP1,CXCR4,DVL2,CXXC1,COIL,FXR2,KDM1A,GTF2I,RALYL,CCNH,FNDC8,H1-5,ACTL6A,MFAP1,AGGF1 |
| 9.016e-03 | -4.71 | AP1M1 (adaptor related protein complex 1 subunit mu 1) | protein interactions | 8907 | 213 | 76 | 19454 | 5460 |
ESR2,SRPK2,NMI,APEX1,TRIM27,AP1G2,ALB,ZNF655,BRCA1,SMAD2,SP1,MYC,ATF4,CUL3,CIAO1,HNRNPC,FXR2,FBXW7,LDOC1,MARS1,HSPA5,RPA3,DVL2,NKAPD1,HSPA8,TIFA,TLR2,MEA1,EP300,RPA2,ZCCHC17,FGFR1,HEXIM1,THAP6,TFIP11,MTF1,PRKAB1,EEF1E1,ARHGAP1,FTH1,AFTPH,RBIS,NKAP,IAH1,FAM219B,ETV6,COMT,CEP57L1,SEC23A,FKBP4,SSX2IP,LAMP2,ATG9A,GPRASP2,YWHAG,XPO1,DCP2,ZBTB14,UBE2A,PAX6,SAR1B,HNRNPA2B1,PICK1,SCPEP1,SPATA6,CA14,RP9,CTLA4,NECAP1,DISC1,AP1S2,FURIN,GBE1,SP4,PNMA5,NECAP2 |
| 9.068e-03 | -4.70 | ATG9A (autophagy related 9A) | protein interactions | 79065 | 439 | 146 | 19454 | 5460 |
ZBTB42,VPS18,UBAC2,EHD1,KRTAP8-1,USP6NL,MTMR6,NOTCH2,AZGP1,HSCB,P4HA2,RAB5A,SLC38A1,GCC1,LAMTOR1,WDR20,PLEKHJ1,YWHAZ,ATG3,HSD17B3,BTF3,ATG101,MAP3K21,UFD1,STX16,SLC1A3,NDUFB7,RUSC2,ESR2,CHP1,APEX1,MB21D2,PSMD6,LGALS3,AP2M1,POLR3B,FAM83B,FAM91A1,MARCHF9,STX12,SLC4A8,FAF2,TPD52,TOP3B,CFAP68,AP1M1,UBE3A,SCD5,SCYL2,MAP3K11,SYPL1,NDUFA4,RB1CC1,YWHAB,LRRC57,AVL9,YWHAH,FIG4,ATG7,YWHAG,TBC1D5,WDR11,ATG9A,EGLN3,FHIP1B,AFTPH,OCRL,SNX1,SNX2,TRAPPC10,SNX17,USP46,STX5,VPS54,TRIM36,JUP,AP1AR,PICALM,VIPAS39,NTPCR,SYNRG,TPRA1,ATG16L1,ARHGAP1,TMEM209,YKT6,SYVN1,SQSTM1,ARFIP1,RAB29,AP2A1,NAPA,STK11,AP3S2,LGALS8,TRAPPC14,DNAJC10,MGAT5B,GORASP2,TECR,SRC,SNX3,TMEM74,SEC61A1,STX10,CDIPT,CCNF,OPTN,SCAMP2,SMAP2,AP1S2,TRAPPC13,VAC14,TOPORS,SESN2,TFRC,DISC1,MAP1LC3B,BLOC1S3,ZNF581,SNAP29,TBK1,PDE2A,ABCE1,STX8,TRAPPC1,EHD4,TRAPPC4,TESK1,SLITRK5,ZFAND2B,ROGDI,SNAP91,TMBIM6,ANKRD10,EDEM1,TMPO,STX6,VTI1B,MARCHF4,FCHO2,TRAPPC3,CDCA3,LDLR,PTPN1,HDHD3 |
| 9.077e-03 | -4.70 | STK38 (serine/threonine kinase 38) | protein interactions | 11329 | 166 | 61 | 19454 | 5460 |
UBE2M,CAV2,RPA2,MAP2K1,CDK7,SHMT1,FBXL4,UFL1,FBXW7,STK38,RAB5A,RPA3,PEBP1,BAP1,EXOSC1,HSP90AA1,UBE2H,KCNJ2,TXNIP,PSMD14,YWHAZ,STK38L,RETSAT,CCNB1,RAB11A,SMURF1,VIRMA,NCKAP1,GTF2F1,EIF4A3,SH3GLB1,RHOBTB1,CDK8,SKA3,RBM34,ISG15,VDR,TRIM6,TP53,MEPCE,DMPK,SOCS2,PRDM4,EWSR1,FAF1,MAP1B,S100B,YWHAB,MAGOH,CRBN,NCK1,BECN1,AGR2,MOV10,IFI16,EMC4,CAV1,MPP1,GJA1,HRAS,GYS1 |
| 9.089e-03 | -4.70 | human chr3q26.33 | chromosome location | human chr3q26.33 | 21 | 10 | 26134 | 5823 |
MRPL47,USP13,SOX2,DNAJC19,GNB4,ACTL6A,DCUN1D1,PEX5L,NDUFB5,MFN1 |
| 9.092e-03 | -4.70 | SUV39H2 (SUV39H2 histone lysine methyltransferase) | protein interactions | 79723 | 75 | 31 | 19454 | 5460 |
TCP1,LCA5L,POLR3F,GSTCD,TTC9C,CCT7,SMAD5,UBE2V2,LRIF1,MYL12A,CGGBP1,CBX5,PNMA1,SHC1,FAM20C,CEP70,AR,RPL39,KCTD17,CBX7,ROCK2,NME4,KRAS,CHMP2B,CCT8,MRFAP1,EWSR1,KLF3,CBX3,QRSL1,CCT5 |
| 9.092e-03 | -4.70 | TACR3 (tachykinin receptor 3) | protein interactions | 6870 | 75 | 31 | 19454 | 5460 |
REEP6,ATP1A3,TMEM11,DCAF5,PIGA,PPFIBP1,FAM241A,HMOX2,TMEM38B,PKP4,PARL,NUP35,TAC1,EIF2B5,SERINC1,GPR89A,ARL10,LMBRD2,DSTYK,ADIPOR1,TCAF2,RAP1A,ZDHHC17,RAB18,RAB3B,MAVS,RTN4,ATP2C1,TSPAN15,THNSL1,ATP2B4 |
| 9.092e-03 | -4.70 | Cd2ap (CD2-associated protein) | protein interactions | 12488 | 75 | 31 | 19454 | 5460 |
CHMP1A,CAPZA2,STOM,TM9SF1,SPTBN1,TPD52,TOP3B,PRDX3,CD2AP,USP8,CHMP2B,CAPZA1,FLOT1,TMEM263,TNFAIP1,RNF10,MYO6,AP2A1,RPL6,RACGAP1,MRPL23,DAPK3,IFRD2,KCTD10,CHMP5,ERLIN1,CAV1,CHMP2A,TRIM27,TSG101,ATP6V1A |
| 9.092e-03 | -4.70 | MBD1 (methyl-CpG binding domain protein 1) | protein interactions | 4152 | 75 | 31 | 19454 | 5460 |
SMAD1,SLC25A3,RBPJ,SNAPC2,EP300,HAPSTR1,RIGI,PIAS1,EEF1G,FBXW7,HDAC3,SUV39H1,YWHAG,MYC,MDFI,MOV10,SP1,SMAD9,TIAM1,TRIM24,NELL2,PRMT5,ATXN1L,SFRP1,SMAD3,SMAD5,APEX1,CBX5,CGAS,STAT1,COPE |
| 9.092e-03 | -4.70 | UNC5B (unc-5 netrin receptor B) | protein interactions | 219699 | 75 | 31 | 19454 | 5460 |
FGFR1,RND3,BET1,OTULINL,RND2,CDC42,KRAS,EPHA4,STX7,FLOT1,RHOU,RAB5A,IGF1R,LAMTOR1,TUBG1,RHOB,NTRK3,STYK1,ATG9A,FLRT3,DNAJC5,DAPK1,ARF6,RHOJ,RHOH,EPHB6,STX6,CAV1,HRAS,RAB35,GJA1 |
| 9.096e-03 | -4.70 | AP2B1 (adaptor related protein complex 2 subunit beta 1) | protein interactions | 163 | 338 | 115 | 19454 | 5460 |
RPA2,AP1AR,PICALM,FGFR1,HEXIM1,ATG16L1,CFTR,SYNRG,GTF2I,COL3A1,TDRP,FBXW7,CRYL1,RPA3,DVL2,BAP1,SIRT7,MTDH,MEA1,SQSTM1,SPOP,RC3H2,AP2A1,EPHA2,UBE2H,AKT3,DNAJC5,SMURF1,VIRMA,CEP97,DYRK1A,CCNF,SMAP2,CAB39,TFRC,NECAP1,ACVR1,AP1S2,RNF8,FURIN,SGIP1,NUPR1,FBP1,TP53,TNRC6C,MAP1LC3B,NECAP2,THAP1,H3C1,KPNA2,TGFBR2,SMAD4,NOS1AP,SHC1,H2AC4,HDAC6,SNAP91,GAPDH,ARF6,FCHO2,TMPO,SLAIN2,RAC2,UFL1,ADRB2,NSFL1C,RNF11,ATP6V1G1,BMPR1A,TXNL1,NUP50,EP300,LAMTOR1,RHOB,BRCA1,MYO6,SLC38A1,MYC,CUL3,PSMD1,TOMM40,PSMD4,TENT5C,ESR2,AP2M1,AP1G2,EZH2,PSORS1C2,NME1,RAB4A,CSTPP1,AP2S1,ARFGAP1,RAF1,E2F4,ISG15,KIAA0408,TNF,AP1M1,UTP25,SCYL2,HNRNPA2B1,SLC2A8,AGR2,CDC23,VCPIP1,HSPB1,LAMP2,TEX12,XPO1,DDRGK1,TBC1D5,AFTPH,OCRL,MAP1LC3A |
| 9.097e-03 | -4.70 | late endosome to lysosome transport | biological process | GO:1902774 | 19 | 11 | 18204 | 5365 |
CHMP1B,VPS4A,C9orf72,VPS39,CHMP5,CHMP1A,SNAPIN,CHMP2A,VPS4B,CHMP2B,CHMP4C |
| 9.097e-03 | -4.70 | regulation of vascular associated smooth muscle cell apoptotic process | biological process | GO:1905459 | 19 | 11 | 18204 | 5365 |
MIR24-1,IGF1,MIR17,SOD2,MIR21,MIR140,ATF4,MIR210,PDCD4,PPARG,MIR1-1 |
| 9.097e-03 | -4.70 | response to potassium ion | biological process | GO:0035864 | 19 | 11 | 18204 | 5365 |
KCNC1,CYP11B2,CRHBP,ATP1A2,NEK7,CYP11B1,KCNJ10,SLC12A2,NPTX1,MECP2,DLG4 |
| 9.097e-03 | -4.70 | regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | GO:0045091 | 19 | 11 | 18204 | 5365 |
APOBEC3B,APOBEC3G,APOBEC3H,APOBEC3C,INPP5K,MORC2,APOBEC3D,CXCL8,APOBEC3A,APOBEC3F,TOP2B |
| 9.097e-03 | -4.70 | vitamin biosynthetic process | biological process | GO:0009110 | 19 | 11 | 18204 | 5365 |
SLC19A2,CYP27B1,RGN,CYP27A1,SLC19A3,THTPA,AKR1A1,CYP2R1,UBIAD1,AKR1B1,PNPO |
| 9.097e-03 | -4.70 | amine catabolic process | biological process | GO:0009310 | 19 | 11 | 18204 | 5365 |
COMT,SLC6A3,DBH,HNMT,PAOX,PDE1B,MOXD1,CHDH,SAT1,DHPS,SULT1A3 |
| 9.097e-03 | -4.70 | cellular biogenic amine catabolic process | biological process | GO:0042402 | 19 | 11 | 18204 | 5365 |
SULT1A3,DBH,CHDH,SAT1,PAOX,DHPS,HNMT,COMT,SLC6A3,PDE1B,MOXD1 |
| 9.097e-03 | -4.70 | ARMS-mediated activation | REACTOME pathways | R-HSA-170984 | 249 | 96 | 10285 | 3229 |
MAP3K11,NEFL,DUSP10,FGF3,PSME2,PSMD6,HBEGF,PSMB9,IL2RA,SPRED2,SHC3,RAP1A,CSF2,FGF7,JAK1,PSMD12,PSMD14,UBB,PPP2R1A,SPTBN1,PPP5C,ANGPT1,PSME1,PSMD7,FGF17,PSMA4,IL2,FGFR1,PSMC5,PSMB11,PSMB10,PSMA2,PSMB6,DLG4,BRAP,CSK,PSMD3,JAK2,PSMB7,PSMB1,PSMA3,PSMB5,PSMC4,PSMC3,PSMA1,IL3,RPS27A,SPRED1,PSMD4,PHB1,SHC1,RASGRP3,PSMB4,SEM1,DUSP1,HRAS,KIT,LAMTOR2,PPP2CB,IL5,PSMB2,PSMD1,PEA15,PSMA6,FGF16,IL2RB,LAMTOR3,CAMK2G,VWF,CUL3,PSMC1,RAP1B,MAP2K1,KRAS,UBA52,FGF22,WDR83,RAF1,PSMD10,FRS3,SRC,DUSP9,FGF10,MET,PAQR3,FGF23,PSMA5,SPTAN1,PPP2R5E,PSMB3,PEBP1,IL2RG,YWHAB,DUSP6,PPP2R5A,FGF1 |
| 9.125e-03 | -4.70 | OSBPL10 (oxysterol binding protein like 10) | protein interactions | 114884 | 52 | 23 | 19454 | 5460 |
VAPB,ATG16L1,CDC42,OTULINL,DET1,KRAS,SAP18,CLPB,HSPA8,RAB5A,RHOG,UBXN6,RAB11A,YWHAG,HSPB8,YWHAH,RHOH,SNAP25,VIRMA,ARF1,EEF1AKMT3,RAC2,SEC61B |
| 9.125e-03 | -4.70 | SPINT1 (serine peptidase inhibitor, Kunitz type 1) | protein interactions | 6692 | 52 | 23 | 19454 | 5460 |
TF,HMGB1,CST11,CLEC7A,FAM3C,SMCO4,AQP3,CLEC2B,TMEM106A,TMEM97,ESR2,ELSPBP1,GXYLT1,ST8SIA5,TMEM190,SDF2L1,DCAF4,CLDN11,ZNF250,UBXN6,CFC1,VAMP5,SLC38A7 |
| 9.125e-03 | -4.70 | TJAP1 (tight junction associated protein 1) | protein interactions | 93643 | 52 | 23 | 19454 | 5460 |
BET1,PPME1,FGFR1,VPS18,FHL3,MIS12,DLG1,TMT1A,XPO1,LAMP3,RAB2A,ATG9A,LAMP2,NRP1,LAMTOR1,GJA1,DLG4,ACSL4,APEX1,EGLN3,ARF6,HNRNPL,TRIM54 |
| 9.125e-03 | -4.70 | PELI2 (pellino E3 ubiquitin protein ligase family member 2) | protein interactions | 57161 | 52 | 23 | 19454 | 5460 |
RBBP8,BCL10,PICALM,TRAF6,MDFI,TRIM32,NUP62,TP53,SP4,THAP7,HYAL2,HNRNPL,LZTFL1,HNRNPK,IRAK4,MYD88,CCNF,NEK9,DVL2,TRAF7,ERO1A,RMDN3,PCGF2 |
| 9.125e-03 | -4.70 | FRMD6 (FERM domain containing 6) | protein interactions | 122786 | 52 | 23 | 19454 | 5460 |
MAK16,H1-3,DDX39A,COX6B2,TP53,FTL,TRIM63,KCTD17,NKAPD1,YWHAB,RASSF8,MED4,SSX2IP,YWHAZ,SUV39H1,EXOC5,YWHAG,YWHAH,SFN,PDIA3,VIRMA,ARF6,SNX17 |
| 9.140e-03 | -4.70 | soft_tissue-smooth_muscle-leiomyoma | COSMIC cancer mutations | soft_tissue-smooth_muscle-leiomyoma | 17 | 10 | 16828 | 4835 |
SF3B1,DICER1,JAK1,PTPN11,KIT,CTNNB1,KRAS,BRCA1,SRSF2,TP53 |
| 9.140e-03 | -4.70 | lower_extremity | COSMIC cancer mutations | lower_extremity | 17 | 10 | 16828 | 4835 |
JAK2,KIT,MET,CTNNB1,KRAS,TP53,PTEN,MAP2K1,TERT,PIK3CA |
| 9.140e-03 | -4.70 | salivary_gland-carcinoma-salivary_duct_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-salivary_duct_carcinoma | 17 | 10 | 16828 | 4835 |
FBXW7,TP53,MET,HRAS,KRAS,CTNNB1,SMAD4,PTEN,PIK3CA,STK11 |
| 9.140e-03 | -4.70 | upper_extremity | COSMIC cancer mutations | upper_extremity | 17 | 10 | 16828 | 4835 |
JAK2,TP53,KIT,MET,KRAS,CTNNB1,PTEN,MAP2K1,TERT,PIK3CA |
| 9.140e-03 | -4.70 | adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | adult_T_cell_lymphoma-leukaemia | 17 | 10 | 16828 | 4835 |
SMARCB1,SF3B1,MYD88,JAK1,FBXW7,CTNNB1,KRAS,KIT,RB1,TP53 |
| 9.140e-03 | -4.70 | leiomyoma | COSMIC cancer mutations | leiomyoma | 17 | 10 | 16828 | 4835 |
PTPN11,JAK1,TP53,SRSF2,BRCA1,CTNNB1,KRAS,KIT,DICER1,SF3B1 |
| 9.140e-03 | -4.70 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | 17 | 10 | 16828 | 4835 |
MYD88,SMARCB1,SF3B1,FBXW7,JAK1,TP53,CTNNB1,KRAS,KIT,RB1 |
| 9.180e-03 | -4.69 | tumor necrosis factor receptor binding | molecular function | GO:0005164 | 31 | 16 | 18094 | 5411 |
TRIM37,SIVA1,LTB,FASLG,TNFSF13,TNFSF15,TRAF6,TNFSF8,TNFSF10,TRAF1,TRAF2,STAT1,CD40LG,TNF,TNFSF12,LTA |
| 9.208e-03 | -4.69 | SENP1 (SUMO specific peptidase 1) | protein interactions | 29843 | 126 | 48 | 19454 | 5460 |
UBE2K,PML,NLE1,DERL1,NUP50,LMNA,SNAI2,SSR1,SUMO1,SEC62,CDC42,RND2,OTULINL,ST7,TXN,SNRNP40,RHOJ,PHF12,FBLN5,DKK3,SEC61B,F9,LMNB1,COP1,CAV3,BRINP3,BAG3,KRAS,NUP107,RIGI,MORC2,TMT1A,RUVBL2,TP53,NUP153,ISG15,DDX39A,HNRNPL,DNAJC1,SUMO3,SUMO2,EGLN3,PTPN1,ARL11,RAC2,RHOG,STYK1,SLC25A46 |
| 9.208e-03 | -4.69 | IGKC (immunoglobulin kappa constant) | protein interactions | 3514 | 126 | 48 | 19454 | 5460 |
NGB,PIK3CA,ENC1,PDE6D,CCR1,CCT5,KHDC4,CA8,GNG10,RPIA,SERTAD1,EGFL8,ARL2BP,CDK5RAP3,AGPAT1,UPK1A,PTDSS1,EMC4,PRKX,SCGB1D1,FUNDC2,GTF2B,EED,NRSN1,STX17,FKBP14,HBM,PIH1D1,SEC22B,TANK,TIMM10,SSBP2,CCNA2,DUSP22,FTH1,CFTR,DDX39B,NPB,MTDH,YWHAZ,ASCC1,UBE2H,MYC,BAG3,CD40LG,GABPA,VIRMA,ALB |
| 9.215e-03 | -4.69 | transport vesicle membrane | cellular component | GO:0030658 | 240 | 87 | 19108 | 5553 |
GOSR2,STX1A,VAMP2,ATP6V1G2,AQP2,AP1M1,AP2A1,TMED7,GABRA2,RAB3C,SNAPIN,SLC35G2,SYT2,ATP6AP2,ATP6V1D,SPRED2,CLBA1,CIDEB,VTI1B,SYN3,BORCS5,RAB5C,AP1G2,GAD2,STX5,SV2B,ICA1,GRIA1,SLC4A8,RAB1A,SCAMP5,SLC18B1,STX6,RAB3A,SYNGR2,RAB11B,ATP8A1,CPLX3,STX10,KLHL12,CNIH1,STX12,LMAN1,RAB5A,SYNGR4,DNAJC5,SYPL1,SEC22B,ATP6V1A,TMEM30A,STX17,FOLR1,SYNRG,SYNDIG1,SYNGR3,LAMP5,SYT4,DBH,AP1S2,BCL2L1,B2M,SLC17A5,SYNPR,PRRT1,CD59,SYP,CPE,SLC32A1,ATP6V1G1,SEC23A,SYNGR1,SCG3,SAR1B,RAB3B,SLC35F1,SEMA4C,AFTPH,VAMP1,SLC30A5,VAMP7,SEC13,SVOP,STX16,NCALD,ZNRF1,OPRK1,ATP6V1C1 |
| 9.222e-03 | -4.69 | MTA3 (metastasis associated 1 family member 3) | protein interactions | 57504 | 163 | 60 | 19454 | 5460 |
PHF12,RBBP4,ESR2,DYRK1A,MAD2L1,CUL3,AKT1,SMARCA5,AR,BTF3,FAM219A,KDM1A,BCL6,ATP6V1G1,MBD3,NOTCH2,CDK7,KLF12,KLF3,NACC2,MED31,TCF19,EEF1AKMT3,CCDC71,SIN3A,RB1,GATAD1,TSG101,MYBL2,EED,BRMS1L,SHPRH,FZR1,HNRNPL,HMG20A,ZBTB2,DPY30,EIF3D,BRD3,KPNA1,HNRNPA2B1,CDKN2C,IGF1R,CDK2AP2,RBBP7,H3C1,SSRP1,RAD21,PHF1,MEPCE,MRPL22,SAP30,JUN,SOX2,H2AX,EZH2,STMN2,CDK8,MTA2,RBPJ |
| 9.231e-03 | -4.69 | TPGS1 (tubulin polyglutamylase complex subunit 1) | protein interactions | 91978 | 78 | 32 | 19454 | 5460 |
HNRNPL,CTSB,RHOH,CNTROB,DIRAS3,COX4I1,MAGED2,PPFIA3,PHF21A,MYO6,TPGS2,SSX2IP,SMG8,RAB2A,NDC80,TMED4,GMNN,KDM1A,PIK3R2,TUSC2,FLOT1,CYP2C9,TMED1,TFRC,NACC2,NICN1,TMOD1,TBC1D19,POLR2C,CSTPP1,RHOBTB1,AURKAIP1 |
| 9.235e-03 | -4.68 | Prolonged ERK activation events | REACTOME pathways | R-HSA-169893 | 252 | 97 | 10285 | 3229 |
SPRED1,PHB1,PSMD4,IL3,RPS27A,PSMA1,PSMC3,DUSP1,SEM1,PSMB4,SHC1,RASGRP3,PEA15,PSMA6,PSMD1,PSMB2,IL5,HRAS,KIT,PPP2CB,LAMTOR2,CUL3,PSMC1,VWF,LAMTOR3,CAMK2G,IL2RB,FGF16,RAF1,WDR83,UBA52,FGF22,KRAS,MAP2K1,RAP1B,FGF10,DUSP9,SRC,PSMD10,FRS3,PSMB3,PEBP1,PPP2R5E,SPTAN1,PSMA5,FGF23,PAQR3,MET,PPP2R5A,FGF1,DUSP6,YWHAB,IL2RG,NEFL,DUSP10,MAP3K11,SPRED2,IL2RA,PSMB9,HBEGF,PSMD6,PSME2,FGF3,RAP1A,SHC3,PSMD12,FGF7,JAK1,CSF2,PPP2R1A,UBB,PSMD14,FGF17,PSMD7,ANGPT1,PSME1,PPP5C,SPTBN1,BRAP,CSK,DLG4,PSMB6,PSMA2,PSMB10,PSMC5,FGFR1,IL2,PSMB11,PSMA4,PSMC4,PSMA3,PSMB5,PSMB1,CRKL,JAK2,PSMB7,PSMD3 |
| 9.248e-03 | -4.68 | TRAF6 mediated NF-kB activation | REACTOME pathways | R-HSA-933542 | 25 | 14 | 10285 | 3229 |
RIGI,S100B,MYD88,NFKBIA,IKBKB,NFKBIB,HMGB1,IFIH1,TRAF6,DHX9,MAVS,NFKB1,TRAF2,AGER |
| 9.248e-03 | -4.68 | MicroRNA (miRNA) biogenesis | REACTOME pathways | R-HSA-203927 | 25 | 14 | 10285 | 3229 |
DGCR8,RAN,AGO1,POLR2B,DICER1,POLR2C,POLR2G,XPO5,POLR2F,PRKRA,POLR2I,POLR2L,POLR2D,DROSHA |
| 9.248e-03 | -4.68 | RAF activation | REACTOME pathways | R-HSA-5673000 | 25 | 14 | 10285 | 3229 |
JAK2,SRC,YWHAB,PPP2R5A,HRAS,PPP2CB,MAP3K11,MAP2K1,KRAS,PPP2R5E,PHB1,RAF1,BRAP,PPP2R1A |
| 9.272e-03 | -4.68 | negative regulation of cellular response to growth factor stimulus | biological process | GO:0090288 | 138 | 54 | 18204 | 5365 |
MIR100,MIR20A,MIR214,SMURF1,HTRA1,IL4,MIR342,MIR106A,NIBAN2,MIR503,PPARG,MIRLET7B,CXCL13,MIR149,UBE2D1,MIR200C,ATP2B4,MIR573,MIR204,SOSTDC1,MIR16-1,HGS,MIR195,LEMD3,MIR210,GREM2,MIR424,APLN,MIR885,PTPN1,DKK1,IL12A,CTDSPL2,NOG,SPRY1,EMILIN1,MIR98,GREM1,GPC1,CHRDL1,CER1,TWSG1,CASK,DLX1,IL12B,SOST,MIR1-1,MIR302B,MIR145,SFRP1,TNFAIP6,MIR15A,UBE2D3,SHISA2 |
| 9.272e-03 | -4.68 | cytochrome-c oxidase activity | molecular function | GO:0004129 | 12 | 8 | 18094 | 5411 |
COX4I2,COX7A1,COX4I1,COX7B,CYB5A,COX8A,COX6B1,COX5A |
| 9.272e-03 | -4.68 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | molecular function | GO:0016668 | 12 | 8 | 18094 | 5411 |
TXNRD2,SELENOT,PRDX3,TXNDC17,TXNRD3,TXNRD1,PGK1,TXN |
| 9.272e-03 | -4.68 | G protein-coupled neurotransmitter receptor activity | molecular function | GO:0099528 | 12 | 8 | 18094 | 5411 |
ADRB1,CHRM3,GRM1,CHRM1,HRH3,CHRM5,CHRM4,GABBR1 |
| 9.286e-03 | -4.68 | NAMPT (nicotinamide phosphoribosyltransferase) | protein interactions | 10135 | 123 | 47 | 19454 | 5460 |
CCNF,TENT5C,UMPS,MYC,FBXW11,LAMTOR1,RIT1,ATP1A1,RPA3,SNAPC1,AKAP1,EP300,HSPA8,FBXW7,UFL1,FTL,COIL,WDR77,RPA2,PHB1,FBXO32,TES,ARF6,EGLN3,EDEM1,DPP4,HNRNPA1,XPO1,CD81,AGR2,HSPB1,PEX3,AKT2,IGF1R,HSD17B10,ETFA,KRAS,SAR1B,OLA1,UBE2A,RAF1,TOP3B,MVD,CTSA,TFRC,FURIN,CCR1 |
| 9.286e-03 | -4.68 | BLZF1 (basic leucine zipper nuclear factor 1) | protein interactions | 8548 | 123 | 47 | 19454 | 5460 |
TMED3,KDM1A,BCL6,VPS28,BET1,LMO3,CCNH,RNF146,FRS3,CKS2,TCF19,SCNM1,CINP,SNX3,RHOJ,KCTD9,TCAP,CHCHD3,PIK3R3,PTPN11,PRMT6,RAB2A,LMO2,SPRED1,TTC23,GORASP2,NTAQ1,EXOC8,LTBR,EWSR1,OAZ3,KRAS,PSMA1,ZBTB16,ENKD1,TMED7,CTLA4,SMARCB1,HCLS1,SMAD3,TNKS,PRPF18,ERCC3,XPO1,TRAPPC2L,RHOG,ZNF688 |
| 9.301e-03 | -4.68 | regulation of sodium ion transmembrane transport | biological process | GO:1902305 | 58 | 26 | 18204 | 5365 |
ATP1B3,SCN1B,PRKCE,FXYD6,MIR448,FGF13,CAV3,ATP2B4,MIR24-1,CHP1,ACTN4,SCN3B,SLMAP,PCSK9,MIR192,NETO1,SNTA1,TESC,HECW1,ATP1B1,ATP1A2,FGF12,DLG1,YWHAH,RANGRF,SCN2B |
| 9.304e-03 | -4.68 | cellular process | biological process | GO:0009987 | 14996 | 4475 | 18204 | 5365 |
PRM1,PDAP1,HSPE1,OR2D3,PTTG1,SLC35F6,ATP1A2,OR10G9,ARHGAP25,NAP1L3,ATP5PF,OGN,MAP1LC3A,LRP12,FOSL2,TWIST2,OAS1,DIRAS3,METTL25B,OR8K1,COPS5,EEF2KMT,H2BC11,NLRP6,CD151,CHRM1,TTC8,MIR200C,CCT2,OR6C4,CAV2,XPO5,ILVBL,SVOP,COIL,KLHL1,MARCHF3,RBP2,WASF3,CREBBP,TNFSF18,PROX1,RPL22,WASL,SLC5A6,GCLC,DYRK1A,EIF2D,SPC24,FGF10,TWNK,NCK1,IL2RG,DRG2,NUDT2,MRPL40,PPP1R3C,IDE,FAM83B,SNRNP70,ATP1A3,MRPS23,MRPS21,OR4F6,PSEN1,CD4,SLC19A2,RNF113A,DTYMK,MPHOSPH6,IRF9,GABRB2,MIR31,BUD31,BRCA1,ALKBH5,LIX1,SMAD2,RAB1A,NME4,NAA60,BLOC1S3,ODC1,CDKN2D,OR6M1,PLEKHF2,RPP14,SUPT7L,ST3GAL1,IDH3B,IFNB1,CAV1,TAB1,NECAP2,TNKS,RBFOX2,MED21,SFXN2,CHRM5,MTCH2,CNIH4,TNFSF8,ISYNA1,CYP26A1,PDCD5,KCNJ2,RPS6KA4,SNIP1,LNX2,HTR1F,SSBP1,ACTMAP,MYC,LY6H,GOSR1,MARS1,TDP1,HSPB1,SEMA6C,SLC43A2,FITM2,ITM2A,CYP4F8,MIR106B,MRPS28,GSTM3,CBLN3,HCRT,SOS2,GLRA1,CCR2,F2,RIMOC1,CACYBP,POMT2,CAPN1,ORAI2,TBC1D17,MCMBP,RNF144B,WDR83OS,NEFL,ACVR1,CA14,H1-6,TRAPPC10,AZIN2,OR4D11,ASIC2,STRADB,TAS2R46,DAP,TFB1M,NUDT3,EEF1B2,FRA10AC1,TSEN34,ZNF593,KCNA3,GSTT2B,DNAL1,VAMP2,RABGGTB,USP16,RFC4,NETO2,HSP90B1,CYC1,GABPA,TRIM46,GTPBP1,TMEM198,CARS1,GPR78,HRAS,MBL2,DFFA,KCTD11,LBX1,NTNG2,RAB6A,KLK6,EMC6,MIR145,DBH,MSX1,NKX6-2,RFC5,TMEM144,TRAF1,TAGLN3,LY96,PRKX,VAMP7,RBBP7,ZC3H15,POLDIP3,PTGFR,STN1,FERD3L,IL10,SRSF8,RAF1,ARMCX3,SRSF2,POLE4,KCNK10,EMX1,DESI1,ST8SIA4,YIF1A,MIR30A,PAQR3,FATE1,GSTO2,LYRM2,GAB1,GABARAPL2,ZNHIT1,SESN2,ADH1A,COA1,NFYB,NCSTN,YTHDF2,CHRNA7,EPO,TRAK2,NR4A2,MKKS,IKBKB,CHCHD4,EGR1,DCLRE1C,TOMM70,OR4N2,DDIT3,ENO2,POLE3,COMT,TBCE,RAC2,PLPP4,ADORA3,ADORA1,FGF22,RRP7A,SIX5,COX10,GPR173,CYGB,CFAP418,PCDH19,ATG101,RANBP10,ARHGAP21,RGS1,ABCC5,SKA2,CXCL8,TMEM30A,FKBP8,NOP9,ERCC3,SLC39A13,CLIC4,LCMT1,STK26,TMEM229B,RRN3,MRPS18B,GNAI2,POLL,CD14,EIF2AK2,CRY1,ASF1A,BLCAP,L1CAM,DVL2,TOMM40L,VXN,POLR1D,ACACA,RAB27A,TUBA1A,CD34,FGD2,UGCG,BCAP29,DEFB114,CYB561D2,MCPH1,MIS12,MED31,IRAK1BP1,STX7,STAT1,TSR2,USP3,GPR146,RNF128,PDIA2,INO80E,UBE2G2,EID2B,CALHM2,TNFSF15,NOP53,SSPN,SHLD1,MIR95,RALA,TSNAX,KLK5,H2AC7,TTL,MAGOH,PDCD10,CERS6,DR1,SNX5,KARS1,PRKD3,NAA16,EIF3D,CPNE1,UQCRQ,KLHL24,TRAPPC1,CKS2,PSKH1,ECD,GNAZ,NPB,SMURF1,GNRHR2,EMP2,NOS1AP,MOB3C,PCK2,RHOBTB3,GUK1,JAK1,HACD3,NGDN,PRPSAP1,CD36,TCF21,RPLP1,NDUFS3,LGI3,KCNH1,LDOC1,ARPC3,SRSF10,GJA10,IFI27,SPACDR,NOA1,KHDC4,ADCY3,HSPA13,TIMM29,ELOVL7,VSTM4,OR4Q3,NEURL2,ENTPD3,DCAKD,SERPINB9,ADRB1,EEF1A1,LANCL1,GPC4,PAK5,RPL39,MAP4,IFNGR1,ST13,HAS3,TOP3B,CD79B,JUNB,USP6NL,GRIK1,DMAP1,AP1S2,ENO1,GTF2F1,SLITRK5,STAMBP,NDUFB6,GCA,SPG21,VIRMA,YWHAG,MX2,FGR,IDH3A,PDE6A,ALCAM,CUTA,TMEM74,TLR5,GRM2,C2CD2L,UTP23,UMPS,NINJ1,ZDHHC16,GSKIP,FMO3,CD38,LAMTOR1,DNLZ,FKTN,TLR10,NDP,NAA11,CSGALNACT2,TSPO2,KCNJ3,CHN2,SPATA2,SSNA1,EIF2S1,FUT9,SRI,FGF13,UBXN2B,RPL32,DISC1,SLC11A2,HCLS1,GSTT1,BMPR1B,CFAP97D1,SNRPD2,OR4D9,NECAP1,HSD17B6,NKX3-1,GRPEL1,GPR85,CLU,MED30,CISH,RPL19,RAP1A,SRP14,CYBRD1,TFRC,ELOC,GIT2,TEX264,SARM1,ATG4A,NR2F6,PCBD1,KCNJ10,EIF1AX,SNAPC2,TLR8,NTRK3,EIF2B5,RFXANK,ELFN1,EIF3K,EHBP1,LYSET,PHKB,BRMS1,SEMA7A,SLC38A1,SEC61A2,LILRA1,TRAPPC4,SMUG1,PDIA6,SOX3,FBXO7,AKR1C2,IVNS1ABP,NOB1,SACM1L,BMPR1A,SLC25A23,MRPL51,FGL2,COTL1,TCOF1,PHB2,RAB40AL,LEP,SQSTM1,CENPM,TM9SF4,EPS8,SNRPB,NME1,SLC25A21,PDSS2,MMP28,TNFSF12,CSTF2T,SERPINH1,C1QL3,PIWIL3,SMARCA5,CLDN14,SH3BP4,DAG1,ELOF1,RAB8B,OR5B3,CHAMP1,GOLGA5,METTL22,SENP5,CPSF1,SEC23A,DYNLL1,ARHGAP5,GNB1L,SNX10,GALNT1,FMOD,POLA2,HBB,COX4I1,DICER1,FIS1,BECN1,TOPORS,TNNI3K,TRAPPC3,UBXN10,IGBP1,BANF1,DNAJB9,SUB1,RGN,RPL7,IL1R2,OLR1,ACTL9,GNA14,CCS,SLC19A3,HGS,PRMT2,KCNIP2,MAP2K1,HDAC5,TAS2R40,RABL2B,WDR11,FCGR1A,TSN,BUD23,MIR29C,SLC38A9,OR51E2,SKAP2,SLMAP,NXPH3,THAP7,ISG15,UAP1,GALNT4,SULT1A3,ZNF501,SLC31A1,GDPD3,RMI1,MSL2,ATP6V1C1,BTBD10,SPP1,PLA2G15,DHX9,SDF2L1,RPA3,RAB29,GJB1,GABRG2,DCTN3,ZMAT2,TRIM8,PGAP2,EIF2B3,KCNMB1,RPL29,LIAS,LCA5,PDE1A,OSBP,HRH2,PCDHB1,RLIM,DHRS7,MIR370,RPL10L,IGFBP3,MRPL57,MIR149,AQP3,LSM10,CD81,TCP11L2,ATP2C1,ARPP19,NLRP9,SLC25A51,HSPA5,SOCS5,GPR162,OPHN1,TMEM127,NPTN,MYD88,H1-10,ANAPC15,VTI1B,ICAM2,ALG5,CLDN24,KCNAB1,CLIC2,RPL18,STX8,TSSC4,UNC119B,ATP6V1D,CSF2,OSGEP,RNASEK,RAB18,MAP1LC3B,TPD52L1,FHL3,SFRP1,IGF1R,FBXO32,IFT172,FERMT2,PTGER2,RCHY1,PSMG4,AUH,ICAM3,PGAP3,FTH1,GGH,PLA2G4B,ABHD10,TUSC3,KCNC1,EFNA3,ZDHHC15,PELP1,IL2RB,GBE1,EPHA4,TIFA,FOXC2,PYGB,NEUROG2,GALNT12,CKLF,MIR17,GJA1,RBM38,CNTN1,RAB31,NAB1,GPHA2,SLC25A5,ELOVL1,RB1,IK,LRRC8D,CALML5,RSRC1,LRRC4B,RAB37,RIOX2,NFYA,FOLR1,SDR16C5,DCTD,TSPYL4,TMEM39A,TMSB4X,FBP1,HINFP,ABHD5,MED11,SSR3,ARHGAP12,EPHB6,IL1RAP,TOP2B,ELMO1,CTDSPL2,BCL6,ATP1A1,SLC25A4,AVPR1B,OIP5,GALC,TNF,ACTB,PNO1,FGF3,RBPJ,SF3B1,NAB2,CAPZA1,TMUB1,SV2B,AOX1,GMPPB,EPCAM,RPL15,IMPACT,PPWD1,BPNT2,HELLS,RHOG,MRPL10,DNAL4,IRAK4,APOO,MAPRE1,SUV39H1,CCSAP,TCEA2,IPO8,ATAT1,HINT1,HMCES,SAMM50,ZNF668,RNF139,CBR3,SIAH1,GAPT,TOR1B,TMEM147,SPTSSB,TMEM14A,OR5L1,IMP3,LRRC28,RAD1,SAP18,CRABP2,ARHGAP1,GABBR1,CHORDC1,MSMP,OR4M1,RAP2C,CIAO3,PPP1R1A,RHCG,SKA1,SOST,EPOP,TNFAIP6,CNP,ASCC1,CSGALNACT1,MCM4,SOD2,PTAR1,ACCS,ACTL6B,BRINP1,CDC26,SLC7A9,MAEL,GNAI3,PHF1,HIGD1C,HNRNPAB,RND2,RPE,TOLLIP,EIF4A2,MIR320A,FHIP1B,SIVA1,SLCO2B1,DOHH,SCPEP1,EGLN2,SYVN1,SPRR1B,CDK5RAP3,RPRD1A,LASP1,ROGDI,PLA2G5,SLC25A26,PRND,CFAP73,SLAMF9,EIF4B,VPS39,B9D1,DNAJC24,FAM107A,CLP1,ACP2,ELAVL4,TAPBPL,SLC45A3,KBTBD2,ESD,IL1B,OR4N5,DYRK1B,KCND2,GID8,PCDH9,NUDCD3,RBBP4,TNFAIP3,ATP5PD,MRPL23,CNOT2,UBE2W,ENY2,PTRH2,HMX2,IGF1,ATP6V1G2,NSG1,SLC39A9,SELENON,DNAJC3,FABP4,DTD1,MEF2B,CDC73,IFNA2,DNAJB2,ADM2,MLLT6,TNFRSF1B,KCNIP3,PLCB1,PTH2,RPL10,MCL1,E2F6,PSMB11,EXOSC1,CD80,LPAR2,ACP6,VPS18,GABPB1,DUSP21,NUDT19,ASRGL1,GNL1,GTF2A1,UTS2R,MNS1,DRP2,MED27,DHRS4L1,PAPOLA,REXO2,ADSS2,CCDC65,SSBP3,GPR65,TMEM95,NMI,EDNRA,CLEC6A,MGME1,PLEKHO1,SLC35E1,CARHSP1,PRNP,BVES,OXSR1,DAPK3,FAM149B1,SMN1,CXCL14,CDC42SE1,PDLIM4,PLXNC1,RPLP2,FUT1,TMED1,DLAT,FOXN2,TOM1L1,AGPAT1,IL6,HEXA,NOP58,SOX21,ADIPOR2,ADAT1,OR5AP2,CEP19,LSM5,IFNA10,GNAQ,CD86,ZMYM4,ACSL4,ACVR1C,G3BP2,DNAJC27,MIR223,NKX3-2,RAB23,DDX1,OR51A4,ZDHHC14,TBC1D25,SUCLG2,POLR2C,KLHDC8B,FAM161A,FRS3,RNF10,P2RY11,HCAR1,YIPF5,NTN4,NPTX1,VIP,MECR,TRMT6,RNF26,CCNH,CLEC12B,GTDC1,HBE1,FKBP4,GLRB,RPS13,MIR183,TLR2,PIGA,CHRM3,HSD17B3,TMEM231,SYP,SYNGR3,IL2RA,CLCN6,MAP2K6,HPGDS,WBP2,NUP62,EHD3,TAS2R7,MRPL17,DPM2,NOL7,INTS12,NME2,RGL2,POLDIP2,STX16,ALKBH4,BFAR,NR1I3,CD40,DERL2,MSMO1,SCG5,RLIG1,PDCD1,MRM2,TIMM13,DUSP1,ASB1,EGFL7,UPK1A,LHB,MCAT,ERH,ATRAID,WEE2,SCN3B,ADIG,STX17,ELK4,TIMM21,OPRK1,COX16,SLC52A3,TCP1,OR8B4,TRUB1,OSGIN2,MRPL49,CDK17,ATP6V1E2,SBK2,CUL3,RLN3,RAN,TRIM10,NR2E1,ACAP2,IPCEF1,HMGCS1,RGS6,SLC38A2,RPL31,CMPK1,CAPZA2,HIGD2A,OR4A47,RCE1,BCL9,GTPBP2,EMC8,MRPL41,AP2S1,TRMT11,ADH1B,CNIH1,RETSAT,EID1,GNB4,INSIG2,NECTIN2,VAC14,NEGR1,UQCC2,TOR2A,TAS1R2,ELK3,NT5C3A,LYPLA2,SURF4,CENPW,MAGOHB,DBT,MIR143,CAMP,RCCD1,TCAP,NLE1,IFT52,RBMS2,FIG4,TNNT2,NUP107,CBX7,ADK,GMPS,NDUFAF3,BMERB1,IFI35,TAAR6,MRPL36,CISD1,P4HA2,CDK7,NDUFA2,PRCP,CIRBP,CFAP298,MIR20A,SLC30A7,CWF19L1,OR51M1,ARL5B,TNR,FZD3,CHGA,NAP1L5,CTBP1,SLC25A24,MCHR1,SNRPE,RAP1B,USP14,EDEM1,NCKAP1,HPS6,PFDN2,TMEM170B,TMOD2,FOLR2,CDH13,RP9,SNX33,RTCB,AP5S1,FUNDC1,WDCP,ENHO,ADTRP,MTDH,PDE8A,TMEM115,USP13,NDUFA1,QNG1,NPM3,HSBP1,PEX13,EIF3J,FMO1,PCNA,ATP5F1B,NAT2,EMC2,ZBTB38,SHOC1,SNRPD3,KLHL12,RIMS4,RBM7,NOTCH2,PAK6,FCN2,CLPB,CHP1,DTWD1,TGFB2,S100A11,SNRPA,ZGLP1,RPS27L,LILRB4,ATG9A,ARL6IP5,EGR2,HBEGF,ZCRB1,GFI1,CLVS2,ABHD12,WWP1,TCTA,TAF2,PTPRZ1,CD28,HSP90AB1,FKBP1B,CMAS,CAV3,SMPD2,TNFAIP8,LCA5L,PFDN6,STARD3NL,ATP6V1A,ACHE,CFAP161,VCPKMT,USP8,HTR1A,FCF1,SMG5,DCTPP1,HSP90AA1,SYNDIG1,USP15,EIF2S2,NDUFA12,SNAP25,DAD1,CYP2F1,WDR45,CDK5R1,PSRC1,TRIM36,SASH3,OST4,TMEM47,INPP5K,HTR2A,TUBA1B,TXNDC17,TMSB10,IER3,SNCB,SCNM1,G6PC3,TDRD7,IFNAR1,HSPB2,PEG10,ATP6V0B,YPEL5,DOK6,PMPCA,CLBA1,GLO1,THOC2,TMEM50B,EXOC8,INA,EXOC5,SLC29A1,RHOH,UFM1,DES,SCN2B,RAB9B,DIS3L,OR5AN1,LDB1,STK38L,RPS16,AIPL1,SPCS1,RAG1,FBXW11,SPINDOC,H2AX,ADO,OGG1,QRSL1,CFDP1,RPF2,ERVFRD-1,CXCL10,PLEKHA8,CIDEB,ATG3,GPR176,PPAN,SPHK2,OR5M9,CAB39,TAPT1,ERAS,PLEKHF1,PRPF4,RHOB,AGER,CORO1C,STX1A,EPHA2,RDH11,TRAF2,FBXO31,MRGPRX2,CBX5,NMBR,HRH3,TMEM106B,TRIM6,RPS3,EEF2,ATL1,H1-1,ETF1,LBH,PLAAT3,GALNT2,TMEM50A,CCR3,OR2J3,H2AZ1,NSDHL,JAML,YIPF4,TAMM41,TPM3,RAB39B,NUDT7,CSNK1A1,GLE1,TSPO,TMOD1,KDSR,GNPDA1,RAP2A,DYNLRB2,OR1S1,AAMP,GPNMB,JUP,RPS5,H2BC14,PYCR1,CAPG,SLC25A11,TPRA1,EDEM3,MRPL47,CHRNB2,PCYOX1L,IER2,IL7,OR10G2,SLC6A4,CNTN2,RAD21,CLN8,COX5A,MYRF,HDAC11,HUWE1,POLR1B,CEP97,MICB,CKS1B,FAM3C,NETO1,TSEN54,LRRC8A,FAM13B,GHITM,TFPT,NONO,HELT,VASH1,FGFR1,TMEM87A,SCAMP5,PIWIL4,EMP3,APEX2,ZMAT5,EEF1AKMT3,VPS72,ACBD7,IL13,TMEM14B,MIR34A,VPS4A,DIPK2A,TAF7,GNPTG,SRPRB,SPPL3,MADCAM1,HADHA,GNG11,TOR1AIP2,CDK12,GAMT,GYS1,RIC3,TRIM24,HTRA1,SNX12,ENKD1,ADRB3,TIMM8A,MMACHC,MIR545,EIF3G,ADCY2,KPNA6,B4GALT7,DEDD,GARIN2,DERL1,BAD,LIMS2,CHPF,CDKL2,TSPAN15,NPW,TIRAP,FTHL17,CEND1,PDLIM3,SELENOS,GRB10,TANK,AMELX,UBXN6,DRD3,RSPH1,CDC7,FAM53B,GMNN,OR4B1,ZMYND11,AKAP17A,BACH1,ANXA7,IFT25,RAB5C,RFC3,VDAC2,EP300,RNF103,GEMIN8,VAMP1,TMC7,HSD17B10,OVOL1,RPN1,CATIP,LILRA2,AQP4,ENPEP,HADH,RBFOX3,ECRG4,METTL2A,MTG2,CD9,B9D2,RWDD1,FMC1,SYNE4,TIA1,LST1,RGCC,MYBL2,POLR3F,MIR210,OR8I2,RMI2,RPLP0,RERG,SELL,OR6X1,SIN3A,SNAPC3,CHMP2A,RRAGB,CFC1,APTX,SLC25A42,GPX2,GNMT,THUMPD1,MTA3,SLC1A3,OSGEPL1,SERPINA5,EMX2,UPRT,PNP,JUN,AP1G2,CBX3,ROPN1B,CNNM4,MRPS7,HSPD1,PCDHA5,RSAD2,ZFP64,MIR107,RTKN,BGLAP,PCDH17,STOML2,ASMT,FOXP1,MYO6,KCNF1,SNRPB2,DPP10,IL12B,UBE3A,RNF14,COPE,DUOXA2,MT2A,LRTM2,TXNL4A,RNF40,SYCE3,NRN1,PDYN,TRIB1,ACAT1,NUDT12,NAE1,TICAM2,TRAF6,CHKB,KCNJ8,LAMP5,B3GNT2,ARG2,DYNLT3,MGAT4A,IGSF11,P3H1,KCTD16,IZUMO1,MRAS,CHI3L1,PRSS12,KLRF1,FOS,TAFA1,PRSS37,SLC25A44,DNAJC4,ELP3,FCGR2B,NDUFA5,ACTR1A,STAP1,TYW3,UQCR11,RALB,SPATA25,TEX19,RILPL2,KMT5B,TAF9,SNRPN,KLRC2,CCN3,WNT2,SELENOK,SEC63,OR5V1,ATG16L1,CMTR1,HMGN4,ELF5,IFIT2,TRMT1L,MIR24-1,CCT5,NTRK2,ASNSD1,STARD4,FLRT2,IFI16,NOP16,TLCD3B,METTL14,ACTR2,NBN,HS3ST3A1,CTNNBIP1,KRR1,CORO6,CA12,SNCG,INSM2,TMEM208,PIGK,C1GALT1C1,RND3,PQBP1,TOMM6,BMPR2,LYPLA1,SLC41A1,MRPL50,AKR1C1,TICAM1,COX6B2,MAIP1,EMC9,B4GALT4,SIGMAR1,TAS2R39,UBL5,MIR181C,CHPF2,METTL6,FIBIN,PSEN2,IDH2,SF3B6,MGAT4B,TRIM21,MTMR2,SRGN,FAIM,PTGES3,GXYLT2,ANGPT1,ADRA1A,CDK20,HBA1,PDCL,ARMT1,TACR3,STX5,NUDT4,MEIOB,TENT2,IFNG,TAB2,FAU,LRRC8C,CWC15,RBM23,KLC2,RAB3A,MVD,QTRT2,BRINP3,LSM8,EMC1,IFRD1,CSNK2A1,GHRL,AZIN1,PTPN5,PAEP,ERO1A,S1PR4,IRF8,SYNGR1,HSPA14,VIPAS39,SKA3,NUCKS1,GRAP,EIF4EBP2,ELSPBP1,FKBP1A,CTTNBP2NL,PRPF19,DHX15,NR1I2,CPNE2,TAGLN2,FAM8A1,MAT2A,SEMA5A,THOC3,DDX4,ADRB2,SRSF7,ZNHIT6,REEP6,PRSS1,PRDM4,RAB3B,FKBP2,TOMM22,DBR1,GAS8,TMEM182,PKP4,SPOCK1,DKK1,KXD1,VAMP8,AANAT,RERE,SUGP1,GJB2,SESN3,JAGN1,LTO1,PLD3,GFM1,CD209,ALB,DPEP1,TMUB2,LRP3,SYNGR2,LRWD1,ZFAND2A,MAP2K3,DUSP3,GRXCR1,FXN,ATP5PO,DGCR8,RPL37A,TXNRD2,CDC37L1,PSMB10,MDC1,PRRC2A,CYTH1,GADD45B,IL4,TACR1,ING2,EFNA5,AP2M1,SURF6,SLC25A17,COG1,CPTP,TMEM11,MYH2,TRMO,RPL17,CCL27,ACADSB,UST,HEY2,PDE7A,ZNF518B,CFL1,C1QL2,OPRM1,SETD7,AKAP1,HNF1B,NXT1,MIF,RAB9A,PCSK2,SOD3,EIF5A2,BCL10,FLCN,ALDH1L1,ARFIP1,SOCS2,AGO1,NUPR1,FZR1,FCHSD2,DMTF1,RGS19,KCNB1,CCL5,FAM50B,CDC16,FUT8,IRF4,H1-5,ORAI3,ARF6,TENM3,CHST7,PDCD1LG2,GGCX,H2AB1,PDHA1,MYEF2,MIR214,ZHX3,BOLA3,EXOC3,BOLA1,TAFAZZIN,TMEM107,CCL18,CASP4,RPL6,SDHAF1,NPY5R,WDR44,NUP35,GNG7,TNFAIP1,CD2BP2,GPR89A,ZNF365,MED4,TOP1,LSM3,SUPT5H,TOMM20,MDFI,MIR105-1,MPST,LRAT,OR8G5,KDM2A,CHRDL1,SMDT1,SNX22,CCT8,CYP4F12,CYP3A5,STUB1,SEC22A,KCNMA1,GOLPH3L,RPL28,PLAC8,CXCL12,TESPA1,TEX12,ANP32A,ERLEC1,RPA2,VAPB,NDUFAF2,DUSP18,NGRN,TBCCD1,RBM3,CHMP4C,SCFD1,ANGPTL2,RBM15B,TRMT61A,DAAM1,TP53TG5,CDKN1B,MLC1,S100A6,SLC25A12,CAMKV,DDX46,NAA35,ZNF326,CYP2C18,FAF1,MIR195,HEXB,GABRA2,SNX2,SLC51A,CEP70,TRIM15,SLC35D1,CDAN1,CLCA1,DLG4,ALKBH3,ZNF473,RPL9,ACKR3,CYRIA,CSRNP3,BAG2,TAS2R5,SCD5,MIR1-1,GNGT2,HPCA,NRGN,RPL35,POR,GABRA1,DDX5,NCBP2,TAC1,MDM2,HENMT1,UBIAD1,HTR5A,IL2,TRIM63,PAK2,CYTL1,CAAP1,KIF2A,LAT2,LHFPL4,AR,FCAR,DOLK,MND1,TERC,BUB3,RPL27,PID1,SLCO1B3,CPLX2,B3GALT2,SRFBP1,SMU1,SMCP,RGMA,DCK,PHC1,RPL4,KCNK13,CCL28,KCNH8,GNB3,NRP1,ACP5,FGF1,FUBP3,TMED4,RPS4X,DUSP26,SLC35F1,SLC25A31,GPC1,RPL26,AIFM1,BMP1,GNG3,MAP1B,BAK1,B4GAT1,PRPS1,BRD9,NFKBIA,SAP30,CIBAR1,ASPA,PIP4P2,TAX1BP3,GPR34,SYT4,LCP2,MDH1,SEMA4C,RIMKLB,OR8H3,HM13,RAMAC,UBE2S,TNIK,TIMM17A,TMEM204,HDAC3,SMARCD3,GNG10,IFNK,TKTL1,MTAP,CATSPERZ,ZNF24,PNPLA8,HP,OTUD6B,RPL7A,RBIS,NUS1,INSYN1,RIGI,SMYD3,URM1,TXNIP,PEX5L,SIPA1L1,E2F4,SNAP29,GRAP2,CLIP3,SNTA1,RPL12,DUS4L,SMARCE1,PPP1R12A,CD274,AGPAT5,RCL1,AKT3,ID4,NDST1,HAPLN2,DDX39B,GNAO1,CHMP1A,MIEF1,PTP4A3,ASPM,CDIPT,BAHD1,TMEM100,POLD4,GNRH1,UBE2K,MCM6,VPS54,TRMT10B,RPL7L1,DPP4,MIR32,FEZ1,TBK1,STX6,CLRN2,PRPF31,TBCEL,USE1,CENPP,RAB5A,H2AC1,RARRES2,G6PD,TIMM8B,CCL2,CHCHD2,GLRX5,PHF23,SEMG2,CLXN,DUSP6,GCFC2,GFOD2,NPSR1,SYPL1,NPPC,TRAM1L1,TUBB,CBLN4,DCTN6,PDE2A,EIF5B,ARL2BP,ARL6,LIN7B,TESC,PRR5L,EAF2,KCTD3,OR4K17,FBXW7,STX11,OMG,NLRP1,NPY1R,FGF16,SYK,HILPDA,RAB14,NUF2,CYB5D2,MED9,GPAM,UBE2L3,RASD1,RHOBTB1,CNOT6L,FA2H,LAMP3,RS1,CAPN2,FZD4,AREL1,NDUFAF4,DEK,HS2ST1,STT3A,CDC40,BICD2,BEX3,ST3GAL5,AGK,TPD52,WDR19,PRKACB,BSCL2,CTNNBL1,VEGFA,OR9K2,CLK1,IL23A,PPM1K,FXYD6,SAMHD1,PDE1B,CYP4V2,PRELID1,NUDT16,MTPN,UTP25,RPL35A,ACO2,HIKESHI,PARP11,HSD17B8,CD40LG,UGT2A3,STX18,FAHD1,COX14,TRAPPC2L,MIR140,CSH1,NDUFAF6,KLF3,CHTOP,RB1CC1,LAMTOR3,PRDX1,GPX7,ASB11,GPIHBP1,THOC1,GFM2,CYP39A1,PHAX,MIR15A,ZFAND2B,IL17F,TAF10,NTF4,RASSF4,TCIM,ICAM1,TST,CSTA,ADAMTS20,LITAF,PICALM,PYM1,CTNNA2,AIP,MRPL9,FEN1,PLA2G12A,MTF1,COX8A,AFTPH,LTA,SETD3,CRHR1,IDH1,HNRNPC,RNF126,UBN1,SUMO1,CLRN1,RER1,IRF7,SMAD1,KGD4,ACTN4,RETREG3,LDHAL6B,MPDU1,DDIT4,KCTD15,ZDHHC24,JCHAIN,CCL20,CEACAM5,PCDHB8,SELENOM,FABP7,GSTM2,ATP6V1G1,PGAM1,ETFRF1,RIT1,ACADS,RPP21,IRF6,CLDN9,TF,CPT2,FBXL4,ADAMTS1,DPY30,STBD1,PAK1IP1,KRAS,GTF2H5,ADAMTS10,IL1A,CLDN1,MIR324,ZHX1,SNRPG,UBE2I,APOBEC3F,GJC1,TNKS2,MTM1,GPR22,PTN,AVL9,CYP2D6,OR10A4,RBM22,SERPINB6,SLC38A3,MIR342,TRAM2,NDUFA4,AGAP2,TMEM70,OR10G7,PIM2,ZYX,POLR3H,ACOT6,CDR2L,SOCS3,RBBP8,FTL,MCOLN1,PRDX4,ADGRL3,COQ8B,PPP1CB,PRR19,MEAF6,MTG1,MPC1,NDST3,CDIP1,BTF3,NFIL3,EED,PWP2,UBE2A,ZMYM3,CTDSP2,GDI2,GLYAT,NAA50,TRAPPC13,OSR2,OR4K2,CDK1,ATP6AP2,POLR2D,OAT,SRM,MIR126,RPL23A,ATP1B3,TYW5,SLC25A1,SLC35A1,CDC20,ZSWIM7,DAPK1,FAF2,SLC25A28,SPMIP10,CASK,TPH2,FAAP100,COX7B,PREPL,PHF13,DLX1,MRPS26,RIMS3,AMT,EDEM2,PPIH,PIP4K2C,CDH11,TMEM126A,HSD17B1,SLC35B4,BCL7C,PLSCR1,KCNQ5,MTHFS,LMAN1,BRD3,PRKCA,RAD23B,TBC1D5,CD1C,EIF4E2,TRA2B,GPX3,GUCY1B1,CTTN,ADNP,VIPR1,CGAS,ECHDC1,SPRN,PGGT1B,PEX3,TBC1D13,INPPL1,ELOVL6,GLRA2,SH3GLB1,CXCR4,OR2H2,HNRNPH3,BCCIP,CD226,PYCARD,OR2W1,PITPNB,ABHD17A,ZDHHC8,GPX6,GABRB3,BCL7B,MAPRE2,HMGB1,CD1D,RGS2,H2BC1,MPIG6B,PTK7,CXCR1,CDC42SE2,VPS28,CX3CR1,CCM2,PAQR8,RAB2A,CDKN2C,RAB11A,PPP1R1B,RAB6B,NAA15,MMP21,MAP3K11,DDRGK1,ATPAF2,SLC39A10,CACNB3,ARCN1,PPARG,CLSTN3,B4GALT6,CCDC22,SPCS2,RABIF,F11R,SDHC,MIR193A,UFD1,TMED5,TMEM237,GOLGA7B,PGR,CALHM3,PRKCQ,HDHD5,SLA2,MIRLET7G,EIF4H,RPS20,UPF3B,IL3,EZH2,ADCK1,SRP54,FSTL1,PTGDS,CUL2,MNAT1,AP1AR,FANCG,OR2Y1,IL34,PNPLA4,CCL8,EYA3,ASTN1,DNAJC2,PSENEN,PRDX2,TSHR,NKAP,P2RY1,SRSF1,CMTR2,CHMP1B,NKIRAS1,AZI2,SCN1B,ITGA6,OR8B12,PGAP4,UBE2D3,OR4D2,RRAGA,MRGPRX4,LPAR1,CCNY,CHST10,CTSC,RRAS2,ARF1,SVBP,BCS1L,MIR221,ATP5IF1,NUP50,CRISP1,SS18,NUP153,TM9SF1,TXNRD3,CYP2C8,NCOA5,CARTPT,SLC8A1,UBE2N,LMO4,CCHCR1,GRIA1,RIOK2,CDC42EP2,CREBZF,TNFSF13,HPF1,RLN2,SEC61B,IL22,GSTM5,TEX261,HBM,LACC1,ABCE1,SMCHD1,SLC4A8,LYZL6,JAK2,PTEN,FBXL19,MORF4L1,DDX39A,LRP6,INTS6L,SLC41A3,GALNT17,VLDLR,CAND1,VPS26A,RPS27A,LSM4,MAPK4,UNC50,SMAD4,ARHGAP15,SEMA3C,ASB3,BRS3,PEX26,AIF1L,UBE2V1,P2RY4,NDNF,PHETA2,PYCR2,ASZ1,SPEM1,HYAL2,CENPL,SLC1A1,KDELR2,CTNNB1,CYP2R1,VPS26C,CYFIP2,GPT,COPS7B,CYB5A,RPSA,GK5,CAMK2G,CD164,PACSIN3,POP7,COQ10B,ANAPC2,WDR82,POC1B,ELP6,DHRS4,PHKG1,RPS2,EEF1G,CXCL3,COX7A1,CACNG3,MIR21,ETFA,SFT2D2,FGFBP1,DNM2,SLCO1A2,TSPAN17,CREBL2,CD99L2,UBE2B,OGDHL,SYNCRIP,MAEA,RBBP9,PMAIP1,BAP1,SLC32A1,IREB2,SYN3,FOXD3,HYPK,FGFBP2,LIG3,RPS23,MED29,TSPAN18,PC,MLH3,TRAPPC6B,LRRC8B,NEUROD2,GRM1,PPP4C,GAL3ST4,UCK2,TRAF7,VEGFC,RXRG,PPARA,SNAP91,PELI1,NCKIPSD,PRL,OTX2,TNPO2,TRPC1,LDLR,AURKAIP1,ABHD6,CSK,KBTBD13,NANP,SEC22C,ERP29,COX6B1,BTG1,NPBWR1,NIM1K,THRAP3,LRRC4,RPS17,LDB2,RNASEL,BRAP,H2AZ2,SFTPD,RAB35,JPT2,CTLA4,TSR3,TPST1,PLN,MRPL24,SLC25A20,FAM20B,DNAJC7,CD2AP,NEK2,MARCKSL1,GADD45A,VPS16,UBLCP1,CRADD,GTF2E2,TERT,HS3ST1,RPL24,IL15RA,NDUFB5,MYL12A,GNA11,ALOX5AP,MRPL20,MRPL33,PABPC1,UGP2,TASL,TFCP2,NUDT9,SRPRA,PML,CBR4,OR4S2,PKNOX1,RPS7,TMEM167B,NFKBIL1,STK38,ADIPOR1,TMIGD1,SLC25A3,GNB1,COX19,RINT1,SDS,RPL3,CCL23,OTULIN,ANAPC13,MACROH2A2,PIK3AP1,SLITRK2,SERPINB1,TUSC2,POLD2,CLTRN,OR13A1,LMBR1L,CDH8,NT5C2,ALKAL1,STC1,CRTC2,TOMM7,BORCS5,MYT1L,PET117,PGS1,RPP25,SNX11,MGAT1,TRNP1,EIF1AD,CLDN8,GTF2IRD1,ALYREF,GSTO1,NIPA2,TRIM3,DTWD2,TAAR1,TFE3,EI24,TMEM199,KDELR1,DRAP1,SRSF4,LPXN,UBASH3B,NFE2L2,DNAJB4,HNMT,GCNT3,COX17,PRMT6,NCDN,MPV17L2,MT1A,TCP11L1,SMARCB1,EFHC1,SLITRK1,HACD1,SFXN1,GOLGA7,CBLL1,POLR2G,MCM3,WIF1,FAM151B,CD200,KRIT1,FAM162A,CMBL,SST,KCNJ11,MGARP,GNG2,EIF1B,CALY,STAC3,IGSF21,TESK2,TMCC1,STK16,RNF146,PLCL1,MED17,DOK5,SERINC3,CBLN1,GXYLT1,SPATA6,KIF1C,DLG1,CHST11,SLC25A14,SF3B5,RAB13,EXOSC4,TMT1A,HCST,NSA2,ALG11,MRPS17,STAT2,ABITRAM,MCHR2,CCR5,OR4K13,PDF,RAB28,PPP1CC,STPG4,TOB2,CFAP61,MAP3K14,JAKMIP1,OR4N4,ANKRD49,CTU1,IGFBP4,RIMKLA,TLR7,RASGRP2,NHP2,EDF1,IL5,RGMB,COPZ2,GAD2,OS9,KDM1A,CCR6,GINS3,ZNF345,HCFC2,OSER1,PPY,RNF167,CXCL1,CST11,COL3A1,OR14J1,SPINT2,CA8,CMTM6,FAM20C,RABL3,FEM1B,SEPHS1,AMACR,DEFB1,LTB,TRMT5,IL18BP,FBLN5,HYCC1,TLE1,MIR346,RPIA,ATP5MG,NEDD8,GTF2B,SLC6A8,EPHX1,NUDT1,TULP3,CYP4F22,IL20RB,H2BC9,HTRA2,KLHL3,TAF5L,TRIM54,MYORG,MRPS16,PLCXD3,RPS9,CDKN2AIP,GSTA4,STAMBPL1,SEPTIN7,OR9I1,TYROBP,DOK4,EEF1E1,FASTKD5,THG1L,AK2,KANSL3,SNRNP48,FURIN,MAVS,SSH3,SHC3,DEPDC1B,ZBTB17,MAB21L1,NDUFB7,CDNF,BARX2,IL6ST,GTF2F2,RFX4,TLCD1,BTN2A2,SRSF12,CCL3,ATP5F1A,ID1,YWHAH,MYL6,FRZB,SLC6A7,PMM2,CNTFR,LILRB1,SCG2,MAGEH1,RTRAF,ARMC7,GOSR2,CSNK1E,CLDN22,TIMP3,LIMD2,CDC42,PPIA,PTP4A2,NELL2,ADD2,RAB4A,RMDN3,DEFB124,MOSPD1,MIR200A,MMUT,MFAP1,AIF1,SLC25A27,SDHB,RETREG2,ALDH1A3,LYNX1,MAPKAPK3,MIEN1,CTSD,OLFML3,CXCR3,CHST2,SEC61A1,CEBPG,SNRPD1,GTF3C3,PRPF18,GPR83,PTGER1,OR52M1,GREM2,PTPMT1,CITED1,TBC1D10C,CYP11B1,TYMS,MRGPRX1,NDN,RBM5,DRGX,CDK9,ARMC6,CNN3,FITM1,MOBP,MRPL34,ITGB8,TBC1D24,EMILIN1,ATP5MK,MZB1,PLG,HMG20A,DDAH1,SSU72,ORMDL3,HSH2D,PHACTR1,BCKDK,TOPBP1,NSFL1C,PFDN5,HFE,RAB11B,RHOU,TRAPPC14,DIO1,SEC13,CDK8,EDA2R,CSRP1,SLAIN2,LRRTM2,RUVBL1,PDIA3,PDE12,GRPEL2,SHMT1,HMGA1,CYP11B2,TWSG1,XCL1,COX4I2,DSTN,MLF1,MIR212,SLC16A1,FCMR,SGTA,PAPSS2,CDO1,CD3G,KLHL22,ALG2,NQO1,SNRNP40,STRBP,CHMP5,COA5,SUFU,TNFAIP8L3,PPP2R1A,TNFAIP8L2,GSTA1,NREP,B2M,GABARAPL1,RPS26,GPHN,GTF2I,PRIM2,EIF2B2,LHX2,S100B,LUM,MIR638,PTPN4,APOC2,RBCK1,IP6K1,TMED7,PIP4P1,INPP4A,B3GALT1,HOMER1,ZBED3,RPAIN,KLF4,RPS15,APLNR,MPP1,TLR4,TSSK1B,ARF4,POLR1H,TMEM165,PCGF2,TRIP4,TMEM38B,UGT1A1,EMG1,MGMT,GEMIN7,ITGAV,ANO3,GHR,BRINP2,LARGE1,LAMB2,AVPI1,MAP3K3,SYNJ2BP,NDUFV2,TUBG1,EHD1,FTSJ1,ZC3H7A,PCGF6,ANAPC16,SSR2,NEK7,LEPR,SDC4,TNFSF10,KCTD12,DDX23,PIGC,PPFIA3,ST6GAL1,CIAO1,STK4,VCPIP1,TGFBR2,TP53I3,MSH6,PSMG2,SUSD6,LMBRD1,SYNRG,KLRD1,MET,CPE,UTS2,COQ8A,TSPAN5,CYB5R4,ANP32B,FLRT3,KIT,FAS,CCDC69,PAXX,TMEM219,ACER3,FN3KRP,TMEM88,SLC25A10,KRT7,MIR448,KCNS1,TSG101,PPP5C,E4F1,TFG,FTSJ3,NR1H2,PCCB,AGR2,UBA52,TLR6,EXOSC8,IFNA13,SLCO3A1,RTF2,METTL15,MTERF2,PFKFB2,PPP3CA,HERC4,ITGB5,SLC6A1,MIR182,RANBP1,CLEC1A,AKT1,GSTP1,RHAG,AGTRAP,TXN,GH1,RETN,CCND3,TOX,NPVF,INPP5E,NEUROD6,MT3,SGMS1,UCP2,WTAP,SLC18B1,DKC1,ROMO1,APH1A,SKIC8,CALR,CHCHD1,GRSF1,TTR,ABCB1,RHBG,CDKN3,OCRL,GRIA2,DHX16,DSN1,B3GALT4,PPP1R10,ST3GAL2,SRD5A3,LPCAT3,RBM34,LEPROTL1,ORMDL1,TLR9,PPP2R5A,MGST2,TAPBP,ANXA4,PIGW,UCN,WDR38,TRAPPC3L,POPDC3,CMKLR2,NCAPG2,XPOT,GMDS,MAD2L2,FOXS1,CCSER2,DSTYK,RPL27A,ZBTB33,IQSEC1,CALHM5,SF3B4,MIR130B,OR2AT4,GNG5,SLX1A,GPR137,EMC10,ATXN10,COPS2,SCLT1,VPS26B,GGPS1,AKT2,HS3ST5,ERRFI1,DHPS,FAM89B,UHMK1,SLC37A4,MPV17,CHRM4,LAMP2,EFCAB7,MOB3B,RTP4,TRAF3IP2,BAX,GP9,DEGS1,SEPHS2,PAIP1,ACAA2,MMP9,FBP2,GPM6B,CYP27A1,CHAC2,DNTT,SLC2A8,KPNA1,ERLIN2,FCER1G,SLC7A1,ARL11,TREML1,ELF1,CSNK1A1L,PICK1,AKAP8L,PTHLH,PPIF,CDC42EP3,STAT5A,BPGM,DUSP9,MEA1,CTNND1,MRPL13,OR7D4,SNAP23,MRPL12,SGMS2,MRPS9,PPM1M,CYP1B1,ST8SIA5,ENTPD4,DRD1,PIH1D1,MIR16-1,RDH10,CACNB4,ATP5F1D,EXTL2,OPRL1,MGAT5B,H2AC25,MRTO4,NHERF1,SLC16A4,NGB,POLR2B,EXOC2,UCK1,MAPKAPK5,HDAC6,SGF29,FOXA3,CCAR2,MED22,CREB3,STK11,TMED9,GK2,PPME1,CH25H,ARFGEF1,OR4K1,NOC4L,TMBIM6,ACVR1B,MED10,SAV1,GLUL,VMP1,MRPS18C,NUP37,ASIC1,LACRT,STAR,EGLN3,CMTM7,BIRC2,SLC23A2,PPDPF,YES1,HR,PRKAB1,NPC2,TMA16,OR5K1,SLC2A1,SPTBN1,NIF3L1,CD2,PARP2,SCYL2,TCEA1,KCTD10,UCKL1,XPO1,AK5,NIBAN2,PIGY,ASB8,H2AJ,MIR493,BET1L,OR7E24,PCDHB13,CRYM,CCNB1,GORASP2,GARRE1,RASGRP3,CLDN12,SSRP1,RAPGEF5,NR0B1,SETD4,PIK3R1,MTX2,CCDC47,CPSF2,KCND3,NDUFS6,CPLX1,PRRT1,CCAR1,NF2,LYZ,LAMTOR2,CEP85,NDUFB4,IL15,RPS12,HSPB6,TLR1,GTF2E1,ABHD2,ARHGEF6,LLPH,FABP5,PPM1G,SIT1,MIR455,ABCG2,COX11,FASLG,PMP22,SLC6A11,PIK3CG,HNRNPA2B1,NDE1,IL18,NDUFB10,GTF2H2,CHST1,POMP,TRIM35,G2E3,WRAP53,H2BC17,STAU1,NEO1,OARD1,PDCD4,CACUL1,GNPAT,WDR55,ETV6,SERINC1,DECR2,ADRM1,TIAM1,WDR12,PAFAH1B1,LRATD1,NDUFS2,CDC23,ATP1B1,HYCC2,CHCHD3,ETNK2,TADA3,NFE2,CCL21,HBP1,GPX4,BAZ1B,MTARC2,AP5M1,TECR,SPECC1L,CTNNA1,SHC1,WDR3,PRKCB,PAGR1,AHSA1,TRAF3IP3,MFSD14B,SNRPA1,MAD2L1,CRYGD,NABP1,ATP2B4,MACROH2A1,RIT2,PLS3,SLC35A5,PIWIL2,TIMM10,TPPP,VPS4B,PDHB,FARSA,GREM1,TOM1L2,NFKBIB,GAL3ST1,SOX2,PTPN22,RAP2B,IRF2,TRIM37,C1QC,TTC4,PXYLP1,ABHD14B,SEC22B,RING1,SNAPC1,GKAP1,CPT1B,TCEANC2,POLB,SLC6A3,SMC4,ACTA2,PLSCR3,CRIP1,SLC7A14,SRPK2,REEP3,METAP1,CRYBA1,WBP11,VAMP5,YBEY,POLR2I,ARB2A,PPP1R2,AP2A1,INSYN2A,PLPP6,CRB3,TNPO3,ZMPSTE24,NUDT5,RUNX1,TMEM91,IFIH1,ARHGAP19,MIR421,IFT57,SNX3,SLC25A45,TAX1BP1,CBFB,ERLIN1,LDHB,MSTN,CNTROB,MSRB1,MEF2C,KCTD17,OXCT1,SLC20A1,PRCC,RC3H2,CRAT,GPBAR1,ARPC2,MRPS33,TGIF2,POLR3GL,SMAD5,SOCS4,KDM4B,FGF12,AKIP1,H2AC13,UQCC6,CD83,REP15,KLF9,MARCHF5,MBLAC2,APLN,CLDN6,GATAD1,CREB1,FRMD8,ANAPC4,SELENOF,TOMM40,ZFAND6,PRDX3,PTGES,PLEKHO2,SLC20A2,GPR17,SLU7,ZNF207,DNAJC30,G3BP1,SPON1,FMO2,DNAJC19,HNRNPA1,WWP2,PRICKLE2,NUDT18,MRPL16,SEC61G,BOLA2B,GAS2,RASGEF1C,CGGBP1,ACOT8,HSPB8,PSMD14,RPS28,DDR1,SLC22A8,KTI12,TFDP2,MTRES1,CFTR,XAF1,PSMG3,PLEKHJ1,SLC35E4,NKIRAS2,TRIM23,ANKH,LGI1,ATAD1,TNFRSF14,TIMM23,PSMD10,ICOS,ZNF622,BORCS8,JPH4,S100A10,PREB,MAPK10,DPAGT1,OR10A6,KATNAL1,BATF,BRIX1,MIR23A,ZNF304,MFSD3,STXBP6,OR2A25,MME,YTHDF1,RASSF8,RPS29,PIR,MINDY3,INO80C,MTMR12,SNX14,THBS3,MS4A7,CINP,CNTNAP1,MLN,FGF17,ADIPOQ,APPBP2,ROCK2,RACGAP1,LIN7C,SP1,LIPA,ACOX1,ANKRD50,CYP7A1,OSTM1,RPL23,SFRP4,PTGER4,CCNA2,FUNDC2,STK24,PDE9A,BTG2,RNF20,SLC35E3,RHOJ,STX12,CETN3,SELENOW,FBXO22,CEP41,MREG,ESR2,FZD6,PLAAT5,OSBPL8,EZH1,AASDHPPT,ATP5F1E,RAB32,AK3,ITK,TPBG,GNPDA2,POLR2L,LSM6,CNOT7,AGAP1,TGFB1I1,PLPPR1,GAPDH,SLC17A5,PTPN11,C1QL1,CCL11,SELENOP,MRPS18A,TRIM27,FKBP10,DHRS3,SLC4A10,EVA1A,CYB561,SEC11A,FBXL7,AZGP1,FOXI3,UGDH,DNAAF10,CDK6,PTPRQ,NDUFAB1,ATXN1L,MTHFD2L,GGTA1,ACSS2,SGIP1,IL21,CLEC7A,PEDS1,MITF,H2BC12,PNOC,FHIT,SLC39A7,BLOC1S2,PFDN1,IDO1,PLAA,SKP1,OR10P1,ARRDC3,PHF21A,CTDSP1,CRKL,SLC7A4,ATG4C,MSN,HEATR9,DIRAS2,NRBF2,IZUMO1R,AATF,TMEM126B,OR4D5,H2AC4,GPR160,MLLT11,SPTSSA,GSK3A,PPP1R8,OR1F1,RAMP3,AKR1A1,FAM91A1,SSX2IP,GRID1,G0S2,P2RY10,STXBP1,ATP8A1,BCL2L1,NCALD,BST2,H2AC6,PRMT5,GABARAP,LZTFL1,ISG20,SDHAF2,MT1E,MRPS34,DDI1,RNASEH2C,UBE2V2,DPH3,LMNA,STARD13,GON7,MRPS35,MIOS,TBC1D4,CTSK,SLC1A2,NPR2,CRTAP,RPF1,GPX1,CCNI,TMEM106A,CCL24,AP1M1,UQCC3,CAVIN2,OR4D6,YIPF3,BOK,NPC1L1,CRYL1,WDR77,CSTF3,PIK3R3,SLC35A2,MSX2,GPX5,VWF,MRPL22,INHA,COX6C,ILDR1,RTN4,RGS10,ESS2,NOPCHAP1,SLC38A7,SEPTIN6,ABCC2,MFN1,OLFM3,EXOC1,RPL26L1,MPHOSPH10,SNAPIN,POU5F1,H3C1,OR51S1,RMND1,RCBTB1,CLDN11,LYAR,ELK1,VAV2,PHYH,AQP2,EIF4E3,BCL2A1,SULT1B1,IMPA2,ADGB,MRPL11,LUC7L3,PRELP,WSB1,MT1X,PALS2,GPR37L1,OR10G3,FLOT1,VPS33A,CHCHD6,PPP1R17,MORC2,MAT2B,LRRC69,KCNA2,VDAC1,TAS2R13,CPLX3,USP2,COPS7A,UBB,CAMLG,CFL2,PEA15,GPR26,DYNC1I1,CXCL9,UBE2E2,POLR3B,MIR185,CCL19,PACRG,ADGRE2,ARMC1,TMEM59,ESYT1,PLAGL1,RAB19,THBD,TTC1,GSTM4,HP1BP3,NLGN2,OR52W1,AGGF1,CCNF,SELENOI,LRIF1,THTPA,NFKB1,WBP1L,TESK1,MT1M,HLF,LIPT2,EFHD1,CCL4L1,SUPT3H,PLP1,PSPC1,FBXW4,CLPX,PHKA1,HINT2,MRPL18,SOSTDC1,RPAP2,CYP2C9,HNRNPF,SYBU,FCHO2,ATF3,AKR1B1,SNRNP27,FNTB,CCDC32,GFUS,ZDHHC4,PPAT,SETD5,KCNG3,PCGF3,KLF10,WDR83,UBL4A,EIF4A3,PLSCR4,TMEM108,ESAM,COL1A2,CRHBP,RHBDD3,HNRNPD,NXT2,TMIGD3,SLC7A11,CDH7,PLP2,GPAA1,CD63,DUSP22,CSRNP1,SMAD3,PHYHIP,ISCU,DDAH2,GSTK1,TFIP11,AP3S2,RPS24,ZMYM6,PGK1,TMED3,SCG3,FBXO44,CGRRF1,BLOC1S5,SHOC2,RGP1,SNX1,COX7B2,MKLN1,ISG20L2,MAN1A2,FAH,UTP15,IRF1,SLC30A5,SLC25A32,STYK1,DNAJC5,ADGRG1,MOG,CELF6,EXOSC3,BNIP3L,MIR29A,SYS1,EDC3,SNX17,SMAD9,MECP2,NDC80,AKR7A2,ETFB,GNG13,ATP5MC3,ZMAT3,ISCA2,CHDH,PLCB2,TFPI,OR2A2,AIG1,HNRNPK,ATF4,NOVA1,POLR2F,NRDE2,EXT1,PPID,SLC25A46,PPIL3,SRC,MEF2A,MRPL53,PRKRA,ARL4A,PGM1,TOM1,DHX38,LGR4,USP30,DLST,GPR37,DTL,RPL8,TMEM117,MACROD1,CAMSAP2,BIRC5,SLC39A3,ZRANB2,RBM27,RNF121,NAPA,LTBR,EFNB1,IMP4,SNAI2,DLG3,DNAJC25,MTRF1,CYP1A1,PROK1,HNRNPA0,CPEB1,CPSF4,DHRS7B,VTA1,SART3,CBL,NDFIP1,SOX9,RHEB,PPIG,BAG3,CCR1,MRC1,DRG1,SLC66A2,REG1A,SNRK,CSE1L,CD200R1,XXYLT1,PELO,ING5,TRIM29,DNPH1,ANAPC11,CTSB,PPTC7,STOML3,CYTH2,CDC5L,CCR7,STAT6,RNF8,SF3A1,ELMO2,C9orf72,TVP23B,MBD3,MCM8,HAND2,CFAP20,CXCR6,CHRAC1,LDHA,SLC7A8,RFC2,NAPG,GLRX2,OLA1,RFLNA,RPP25L,H2BW1,RAB1B,ADD1,SLC2A3,LSM2,RPRD1B,LORICRIN,EMC4,SMNDC1,SH3BP5L,CHST9,SLC35F2,ST6GALNAC3,PPFIA2,KLHL15,CCDC186,PDP2,FAM98A,CBLN2,MATN4,MIR146A,TMEM190,PAAF1,NTMT1,IFT22,THAP1,NDUFC2,OR5I1,GTF2H4,CMA1,SWAP70,RUVBL2,DKK3,GSTA2,NEU1,GPR35,YAE1,GPBP1L1,CSNK1G3,F9,IRF3,MAP3K12,PARD6A,STK3,GDE1,RNF34,SLC48A1,NDUFS8,SHPRH,IL12A,REN,GGCT,PPP2R5E,SLC6A2,CCL17,MTMR6,DUSP19,CRYAB,SECISBP2L,SREK1IP1,SPEF1,CST3,RORB,UBAC2,ABCB9,AKAP12,DYRK2,HACD2,TLR3,DDX42,RPS14,TAS2R16,NHEJ1,ABCF1,CLDN3,CASC3,CSNK2B,COA4,YWHAB,RGL1,PPM1D,RP2,KCTD9,TPPP3,CASTOR2,NLRP3,CCL25,TRAPPC6A,ILK,RNF152,EID2,NLRP2,FDFT1,SLC22A12,SH3GLB2,GGT7,LSM14A,CDKN1A,RNF5,PITPNA,PCLAF,MIR98,DUSP10,GTF2A2,GPR15,MYO1B,SLC22A17,RANGRF,DNAJC10,FGF7,CDK5,CERK,RSL24D1,CLDN4,KLHL9,ARL4D,NEK9,RDH12,FCGR2A,ING1,PHB1,MID1IP1,HAUS2,EXD2,CYP17A1,CLVS1,RANBP6,PPT1,GRM8,MUL1,GINS4,CX3CL1,ATP6V0E1,RETREG1,SLC15A2,UFL1,CXCL13,PPP2R3A,CD247,BET1,CAP2,TLCD2,TRA2A,CCDC134,FYTTD1,FOXJ3,HOMER3,B4GALT3,ASB7,ST7,PIWIL1,FAR2,CFAP91,DROSHA,SLC22A6,LRFN3,METAP2,KPNA2,WDR6,CDC123,LGALS3,DET1,SDHAF4,RAB3C,GPM6A,CYP27B1,RBMX2,ST3GAL4,CER1,USP39,CYB5B,MRPS11,IFI6,RARS1,SORD,JADE1,NUP42,TIMP4,TRAM1,MARVELD1,MGP,RAB30,ZNHIT3,TMEM33,HSPA8,SLC15A1,PPIB,LILRA3,INTS10,SNX20,PTPN1,KIF3B,SSR1,OR10A7,SLC25A39,OCEL1,LYZL4,TRMT13,FADS2,MPG,API5,SDCBP,SPCS3,MAP1S,TP53,RCVRN,PYGM,OR8B8,UQCRH,STARD5,MIRLET7B,PAIP2,CCND1,HIRA,PPFIBP1,REEP4,CNR1,SNAPC5,MRPL52,SOD1,PFDN4,XBP1,CD59,PNPO,INSYN2B,NUBP2,KCNK17,RPL13A,EHHADH,TUBB4B,GLCE,PRKCE,ATP5MC1,LCP1,PARL,ATF1,DIO2,KRT8,TAF11,PIP5K1A,CKB,PPP3R2,RPGRIP1L,PCSK9,MIR187,MIR125A,B4GALT1,NYAP2,HACD4,ACO1,NCR3,TSPAN10,FKRP,LBR,ITGA2,PDRG1,CCT7,NPY,WNT7A,ARFGAP1,VSTM2A,CEBPE,TGFB3,SIAH2,OR4E2,CA10,GNRH2,DELE1,MRGPRX3,DUSP14,OR10Q1,VDR,RGS5,RAB3D,DYNC1I2,TXNRD1,RHCE,OXTR,KICS2,CXCL11,SPRED1,DIO3,CLK4,LPAR6,FAM83C,SIRT7,GRPR,TCF23,COX6A2,PYROXD2,SNX18,FBXO9,DNAJB6,SFN,AQP11,EHD4,NACC2,AJM1,MMP20,B3GALNT1,JKAMP,MIR96,UBA3,FAM53C,ATG7,OR2F1,OCIAD2,SH2D1A,FHOD3,ZBTB16,KCNMB2,BABAM1,KIF3C,CHMP2B,CDC42EP4,OPTN,SRXN1,HHIP,CASP12,PRKAG1,TUFM,SCAMP2,CIB2,TP53INP2,SLC35C1,PAX6,UQCRC2,GFPT1,TPPP2,CRYZ,WNT10B,OR5A2,SAR1B,LMNB1,SPRY1,OR13C8,GNPNAT1,HAX1,MIA2,GPD2,TENT4A,ACTL6A,PPP2CB,DRAM1,FOXP3,MX1,CA2,AHCYL1,UTP6,EIF4E,SDC2,POPDC2,TP53INP1,GADD45G,PADI2,UQCRC1,CETN2,BBS5,BORCS6,LRRTM1,GLTP,POP5,THOC6,CRYGB,IMMP2L,MACIR,SLC6A12,MOSMO,MMP14,ABHD4,PIAS1,DIRAS1,VAMP3,ACOT13,CDK4,XRCC5,CYRIB,CYP21A2,APOBEC3A,DMPK,C1D,TACO1,SLC12A2,MRPS25,LRRC40,SLC16A10,LRRC61,SPMIP6,GNG12,CCDC42,GPR75,CLEC9A,RPL10A,IGF2BP1,DNAJC1,SLC35B3,RBM42,KIN,RASL10A,HSCB,ZDHHC17,S100A8,NOG,PRDX6,ZC3H11A,SELENOT,MALSU1,TRIM5,SIGLEC5,PPIC,APOBEC3C,MAK16,FAM83A,CCR4,PROM1,PITHD1,BOLL,PCYT1B,CCIN,HNRNPL,ABHD16B,TMOD3,TRMT112,TRIM32,GPR171,RAB33B,YKT6,RAB33A,MED23,VSIR,APEH,UBAP1,DCUN1D5,LGALS8,NAIF1,RBM17,ODR4,OR1M1,CERS2,STMN2,SOX14,ELOVL4,RXFP2,PTDSS1,CAMK1,LMBRD2,TNFRSF9,NDUFB8,PIK3R2,VKORC1L1,KLF1,SRP72,CDCA3,SLC6A6,CCL1,YWHAZ,OSM,AMIGO1,VEZT,TERB2,MIR301B,CD248,BORCS7,VRK1,CTSA,ALKBH2,MTA2,SNX24,METTL21A,MGST3,SATB1,GTF3C4,TIMP1,SEC62,RPS11,NSMCE3,TMEM170A,UNC45A,ALPL,PPM1B,RRM1,FGF23,EIF3E,BACE1,CD58,MACO1,RNF41,THY1,PMP2,PDE4B,RBM41,TFEB,LRP10,CCDC85B,H1-3,OLFM2,TMEM176B,SUPT4H1,P2RY12,ROCK1,STX10,SYT2,MPZ,RPS10,CDSN,F7,ARFGAP3,PIK3CA,CD47,SLC13A5,ATP5PB,CACNB2,NMRK1,ELOVL3,RAB22A,NLGN1,RGS7BP,APEX1,NPY2R,CHST13,ZC4H2,MAP3K21,COX20,SPTAN1 |
| 9.306e-03 | -4.68 | reactive oxygen species degradation | BIOCYC pathways | META_DETOX1-PWY-1 | 7 | 6 | 902 | 319 |
GPX1,SOD1,SOD2,GPX3,GPX2,SOD3 |
| 9.309e-03 | -4.68 | TAF1 (TATA-box binding protein associated factor 1) | protein interactions | 6872 | 245 | 86 | 19454 | 5460 |
UCKL1,ITGB5,TAF10,MAX,JUN,PPP2R1A,ELF1,KRAS,ASF1A,CA10,FOXP4,PAX6,RERE,RPL31,EWSR1,DDX23,HAX1,TAF7,ZCCHC10,SPTAN1,SUMO2,TMEM248,SIN3A,MYEF2,YBEY,GATD3,KLF3,ZNF362,MSX1,COIL,PRKD3,FOS,NUP50,FTSJ3,BAX,RIT1,H1-1,LMO2,MYC,LDB1,BRMS1,TAF11,BTG3,ELK3,GTF2F1,PHF21A,CDK8,TAF2,CD14,TP53,EMILIN3,SMAD1,H3C1,TMX3,AKAP8L,TAF9,BRD3,FOXP1,MOV10,ACOT8,GTF2E1,CSNK2A1,HTRA1,MDM2,COQ8A,SMAD3,RB1,HECTD1,CCND1,EDF1,NTPCR,CCNA2,CDK7,KDM1A,HMGB1,SNAPC1,SPATA25,SMAD2,SUB1,AR,TENT2,VIRMA,ZNF330,GTF2A1,CFAP298,UBE2I |
| 9.309e-03 | -4.68 | ITSN1 (intersectin 1) | protein interactions | 6453 | 245 | 86 | 19454 | 5460 |
DVL2,RHOU,TRIM5,VLDLR,RAB5A,UBE2K,KRT222,STX7,MRPL20,PACSIN3,SPTBN1,CDC42,SETD3,LMO3,LMO4,FGFR1,PICALM,GOLGA5,SMAP2,KTI12,CSNK2B,CYTH1,AP2M1,SF3B4,SIAH1,RBBP4,APEX1,DES,VIRMA,FCHSD2,RAB11A,RNF40,BTF3,DNAJC5,LAMTOR1,GCC1,MYO6,BICD2,RHOB,AP2A1,NCKIPSD,SNX5,PIK3AP1,ZYX,SOS2,SNAP23,KRAS,WASL,HNRNPK,HSPE1,RUVBL1,PDE2A,FLOT1,TFG,TNRC6C,WBP11,NECAP2,EEF1A1,PPFIA2,DISC1,NEFL,AP2S1,SGIP1,HRAS,RAB35,DNM2,TSG101,IGBP1,DSTN,GJA1,ARF6,SNAP25,GNPTG,SPTAN1,FCHO2,STX6,PIK3R1,PDIA3,ATG9A,TRIM8,PFDN5,EXOC1,BECN1,SNRNP70,MED4,CBL |
| 9.317e-03 | -4.68 | endometrium-carcinoma-adenocarcinoma | COSMIC cancer mutations | endometrium-carcinoma-adenocarcinoma | 51 | 23 | 16828 | 4835 |
SMAD4,KRAS,IDH1,FGFR1,PTEN,TP53,KIT,MET,FBXW7,CDKN2C,JAK2,GNAQ,STK11,SF3B1,HRAS,MSH6,PIK3CA,SMARCB1,CTNNB1,GNA11,RB1,AKT1,PTPN11 |
| 9.323e-03 | -4.68 | negative regulation of steroid metabolic process | biological process | GO:0045939 | 34 | 17 | 18204 | 5365 |
NFKB1,ATP1A1,ERLIN1,SNAI2,MIR98,DKK3,INSIG2,PROX1,SOD1,GFI1,UGT1A1,NR0B1,CH25H,ERLIN2,MIR342,CYP27B1,MIR185 |
| 9.323e-03 | -4.68 | response to interleukin-4 | biological process | GO:0070670 | 34 | 17 | 18204 | 5365 |
STAT6,HSP90AB1,MRC1,TUBA1B,NFIL3,CCL11,IL2RG,CDK4,CITED1,STAT5A,HSPA5,XBP1,JAK1,IL4,XCL1,RPL3,PML |
| 9.323e-03 | -4.68 | regulation of type 2 immune response | biological process | GO:0002828 | 34 | 17 | 18204 | 5365 |
IL18,SOCS5,IFNB1,IDO1,BCL6,NLRP3,XCL1,IL4,NDFIP1,ARG2,IL6,STAT6,RSAD2,CCR2,CD86,IFNA2,CD81 |
| 9.341e-03 | -4.67 | RRM | prosite domains | PS50102 | 209 | 74 | 12186 | 3388 |
NONO,SNRNP70,RDM1,RBM7,SRSF2,SRSF10,RBM18,TRA2B,HNRNPA2B1,RBFOX3,RBM22,IGF2BP1,SF3B4,ZCRB1,EIF3G,RBM15B,HNRNPA1,HNRNPC,HNRNPDL,NCBP2,POLDIP3,RBM42,ELAVL4,TRA2A,HNRNPL,SRSF8,RBM34,SART3,SYNCRIP,EIF4H,SNRPA,SNRPB2,PSPC1,TIA1,GRSF1,G3BP2,HNRNPAB,RBM38,PABPC1,RBM27,HNRNPF,PABPC5,RALYL,SRSF12,HNRNPH2,RBM23,PPIL4,ELAVL2,ALYREF,RBM5,HNRNPD,RBFOX2,RBM41,HNRNPA0,RBMS2,G3BP1,RBM12,RBM3,EIF4B,EWSR1,CIRBP,CPEB1,CSTF2T,HNRNPH3,BOLL,SF3B6,MATR3,SRSF1,CELF6,SRSF4,UHMK1,MYEF2,SRSF7,RBMX2 |
| 9.346e-03 | -4.67 | TRMT112 (tRNA methyltransferase activator subunit 11-2) | protein interactions | 51504 | 81 | 33 | 19454 | 5460 |
NCSTN,ATG16L1,BUD23,SF3A1,LUC7L3,PIH1D1,SF3B1,KRAS,HSCB,UFL1,ATG7,CUL2,WWP2,UBE2H,RIT1,FAS,ATG3,DCAF4,TRMT11,EFNA3,SYNCRIP,CCNF,SRSF1,PHB1,EGLN3,SRSF10,DHX15,ESR2,RPL10,FZR1,CAND1,DYNC1I2,THOC1 |
| 9.346e-03 | -4.67 | FAM114A2 (family with sequence similarity 114 member A2) | protein interactions | 10827 | 81 | 33 | 19454 | 5460 |
RPA3,TMT1A,EWSR1,EFNB1,GPSM3,GAD2,DERL1,AKAP1,RAB5A,CAMKV,STAU1,SEMA4C,NAA15,SEC62,CLEC2B,OTULINL,SIGLECL1,SH3GLB1,SCN2B,CD274,HSD17B11,SEC61B,SPPL3,SNX2,ACTB,RAB2A,GPR17,MORF4L1,LRRC4,RAB5C,COPS5,NDUFV2,PDAP1 |
| 9.346e-03 | -4.67 | CUEDC1 (CUE domain containing 1) | protein interactions | 404093 | 81 | 33 | 19454 | 5460 |
MYO6,UBE2E3,NTAQ1,UBE2E2,LRRC73,SURF6,SMURF1,PTP4A3,APLNR,TOM1L1,RPS10,SPPL3,PLAC9,NFKBIA,RBPJ,WWP1,TOM1L2,DUSP22,RPL15,ISG15,MYL12B,MTMR6,RPS14,DUSP19,SRPRB,OIP5,TOM1,ERLEC1,ARRDC3,TRIM5,LDLRAD4,WBP2,TEX264 |
| 9.346e-03 | -4.67 | CSTB (cystatin B) | protein interactions | 1476 | 81 | 33 | 19454 | 5460 |
CTSB,DCUN1D1,NUP35,CCNF,TRIM24,UBE2H,MDH1,CUL3,CST3,PTPN11,MAT2A,AKT1,CTSD,MYC,RACGAP1,BAG3,DDRGK1,MTPN,UFL1,H3C1,RAD21,IRAK4,GSTT1,RPS28,HSPA8,ABCE1,NUDT19,ANXA7,PIH1D1,HEXIM1,E2F4,DET1,CFTR |
| 9.346e-03 | -4.67 | PEX1 (peroxisomal biogenesis factor 1) | protein interactions | 5189 | 81 | 33 | 19454 | 5460 |
OSTM1,EXD2,THBS3,BAG2,AKAP1,PXMP2,PEX26,PRKAB1,CHRM3,UBA52,MGARP,PPP2R1A,OTULINL,DTWD2,LMBR1L,PTPN1,SSR2,EEF1AKMT3,CIB2,RMDN3,EGLN3,NAA11,UBXN6,FAM174A,CUL3,MARCHF5,FAS,FBXW11,CHCHD4,FIS1,PEX3,HAX1,ICAM1 |
| 9.353e-03 | -4.67 | regulation of secretion | biological process | GO:0051046 | 605 | 205 | 18204 | 5365 |
ADTRP,SMAD4,PFKFB2,DRD3,VPS4B,VAMP8,IL1B,SPP1,TGFB3,DPH3,P2RY4,PPP3CA,WNT7A,SLC6A1,NPVF,RETN,RALA,OXTR,JAGN1,RAB3D,FGF10,TGFB2,IL1A,OSBP,PPFIA2,IGF1,UCP2,ENY2,RIMS4,CARTPT,RAB3A,CNR1,GNAI2,XBP1,GHRL,BAD,SLC4A8,RAP1B,CRHR1,RAB27A,HGS,CHGA,PRKCE,CPLX2,CRY1,PRKCB,NR1H2,OR51E2,TSG101,STXBP1,JAK2,NLRP6,OPRM1,VEGFC,SNAP25,PARD6A,IL12A,HTR2A,REN,CPLX3,LILRB1,KCNA2,PRL,RAB9A,RASL10B,MIF,BGLAP,PPIA,GNAO1,PTGES,ERP29,CREB1,RSAD2,SFRP1,ARFIP1,IL6,RIMS3,FGR,HCRT,PREPL,IL12B,MYO6,CASK,ACVR1C,ACSL4,CCL5,KCNB1,INHA,HADH,MIR146A,SYT4,TACR1,RGCC,TNFRSF1B,PLCB1,PCK2,GNAZ,ILDR1,FERRY3,MEF2C,LGI3,EFNA5,FKBP1B,VPS18,UCN,SNAPIN,HTR1A,CHMP2A,ACHE,STXBP6,SELENOT,NKX3-1,S100A10,S100A8,FCGR2B,HFE,CXCL12,SCG5,GOLPH3L,CDK5,STX1A,SYK,VAMP7,LACRT,RAB33B,KLRC2,RHBDD3,CRHBP,AVPR1B,CCN3,ASIC1,RAP1A,NDUFAF2,STC1,TNF,APBB3,ADIPOQ,ADGRE2,ARF6,GRM2,C2CD2L,F2,CCR2,PICK1,VAMP3,RAB5A,NLGN2,TLR2,SLC12A2,GJA1,CFTR,CD38,CD2AP,P3H1,SRI,GNA11,NPY5R,CACNB4,CHRM3,DNAJC1,SYBU,SPHK2,NPSR1,VAMP2,NHERF1,MAP2K6,SYP,CD200,LRRC8A,LEP,TLR4,PTPN11,ADORA1,ADORA3,UQCC2,SCAMP5,PPID,KCNJ11,GABBR1,P2RY1,FGFR1,RAC2,VPS4A,IL13,RAB8B,NEO1,IFNG,NLGN1,SDCBP,DYNLL1,TIAM1,SDC4,OPRK1,SLC16A1,SV2B,PPARG,CPLX1,OSM,TSPO,SNCG,CHRNB2,SLC38A2,FGF23,C1QTNF1,SLC6A4 |
| 9.359e-03 | -4.67 | CDC6 (cell division cycle 6) | protein interactions | 990 | 120 | 46 | 19454 | 5460 |
CDK1,HCST,CCNA2,CDKN1A,TANK,PPP2R3A,UBE2K,DDX5,SQSTM1,ORC6,DDX39B,RIT1,MCM8,PSKH1,MCM3,MYC,CCNB1,GPR17,CDC20,B3GALNT1,MANSC1,CCNF,TNFRSF1B,FURIN,TSPAN3,PNMA2,E2F4,TP53,CDK4,RPS27A,MCM6,HUWE1,KRAS,TGFBR2,CCL2,PCNA,AKAP8L,LAMP3,LAMP2,ORC5,MICB,OS9,LRWD1,FZR1,TOP1,CDK6 |
| 9.359e-03 | -4.67 | ITGA5 (integrin subunit alpha 5) | protein interactions | 3678 | 120 | 46 | 19454 | 5460 |
VIRMA,RABIF,RHOJ,LGALS3,ATP1A1,ILK,ATP1B3,RHOB,LGALS8,RNF40,RAB2A,CLK1,LCN1,RHOU,TMEM106B,UBAP1,STAMBP,TMEM106A,OTULINL,RND2,CDC42,CD59,ST7,CAV1,ARF6,RHOH,RAC2,RAB35,HRAS,CBL,ARHGAP5,RHOG,SPP1,CD9,CD81,KRAS,L1CAM,PICK1,EWSR1,MMP9,RND3,ITGB5,NCR3,SFTPC,TOP3B,ANGPT1 |
| 9.383e-03 | -4.67 | cellular response to carbohydrate stimulus | biological process | GO:0071322 | 106 | 43 | 18204 | 5365 |
TWNK,FKBP1B,PRKCB,MIR16-1,CMA1,TRA2B,MIRLET7G,IGF1R,CLEC7A,CLTRN,GPX1,MIR15A,MAP2K6,PIK3CA,PAX6,SIN3A,KCNB1,UCP2,MAP2K3,RAF1,ICAM1,SMAD3,SLC29A1,CYP7A1,OPRK1,CCDC186,FBP1,PPARA,AGER,MIR146A,LEP,NPTX1,SMAD4,SELENOT,PLCB1,GCLC,PCK2,XBP1,KCNJ11,MIR320A,PPP3CA,RAB11B,SMAD2 |
| 9.409e-03 | -4.67 | WTAP (WT1 associated protein) | protein interactions | 9589 | 185 | 67 | 19454 | 5460 |
ALB,PRDX2,TXN,DYNLL1,TUBB,ACTB,TAB1,ESR2,VIRMA,SNRPB2,MYC,SMARCA5,SUB1,RNF40,PPP1CC,TUFM,RBM15B,BRMS1,ZSCAN25,SH3BP5L,YWHAZ,HSP90AA1,PRSS1,DDX39B,EXOSC4,HSPA8,H2BC12,DDX5,BCL6,HSPA5,ATG16L1,BORCS6,LMNA,MED23,METTL14,DYRK2,TRAPPC6A,WTAP,SRP14,H2AZ1,MAP2K6,CORO1C,CPNE1,FZR1,PRNP,TOP1,KXD1,IFI16,PRDX1,TPM3,CSTA,SNRNP70,AGPAT1,HSD17B10,PSMA1,KRAS,LSM4,PSMA5,HNRNPK,SSRP1,CBLL1,EEF1A1,DDX39A,NME1,NGB,PDHA1,CAPZA2 |
| 9.415e-03 | -4.67 | extrinsic component of presynaptic membrane | cellular component | GO:0098888 | 6 | 5 | 19108 | 5553 |
PICALM,STXBP1,SNAP91,AP2M1,SNAP25 |
| 9.425e-03 | -4.66 | RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein) | protein interactions | 9136 | 117 | 45 | 19454 | 5460 |
CSNK2A1,DDRGK1,TRA2A,GRSF1,IFI16,CHCHD1,EED,PWP2,KRR1,NOP58,THOC1,H2AX,SOX2,IMP3,RPL18,NUPR1,RPL3,RPS24,DHX9,SNIP1,PPAN,KRAS,DNAJC8,MYC,THOC6,RC3H2,PHAX,CCNF,SMURF1,SRPK2,RPF1,UBLCP1,ATG16L1,UTP15,RPA2,LMNA,PPARG,MAP2K1,RAP2A,SIRT7,UTP23,WDR3,STAU1,RPL4,FBXW7 |
| 9.425e-03 | -4.66 | CMSS1 (cms1 ribosomal small subunit homolog) | protein interactions | 84319 | 117 | 45 | 19454 | 5460 |
SNRNP70,ANKRD49,SMAD4,ACTR3B,DDRGK1,SURF6,ZBTB2,MDM2,CAND1,RPS16,FZR1,PRR3,KRR1,SART3,CCM2,LLPH,SKA3,SOX2,KIAA0408,E2F4,RAF1,ATP5PB,RPS13,H1-6,RPL23A,RPL31,MAPRE1,RPL26,MYC,RPL10,TAX1BP1,MED17,RPS9,FGFBP1,DOK4,LMBR1L,RPA2,FOXS1,RBMS2,H1-5,UNC45A,UTP23,FTL,UFL1,RPA3 |
| 9.425e-03 | -4.66 | RSF1 (remodeling and spacing factor 1) | protein interactions | 51773 | 117 | 45 | 19454 | 5460 |
HSPA8,EP300,SIRT7,NLE1,HSPA5,HMGB1,NUCKS1,CDK1,LMNA,TRIM24,MACROH2A1,ZNF330,VIRMA,APEX1,SNRNP40,MYC,SMARCA5,PDCD4,SP1,YWHAZ,RING1,EWSR1,SSRP1,H3C1,HMGN4,H2AX,MSX2,DHX38,TP53,EZH2,CBX3,CHMP4C,H2AZ1,MYL12A,ZBTB2,PRNP,TOP1,CSNK2A1,WDR11,NFKB1,HMGA1,BAZ1B,FAM133B,ZDHHC15,BRD3 |
| 9.439e-03 | -4.66 | MPHOSPH6 (M-phase phosphoprotein 6) | protein interactions | 10200 | 84 | 34 | 19454 | 5460 |
LRIF1,SRSF10,ZCCHC7,FZR1,PWP2,RPS20,ZHX1,EIF4E2,DNM2,HSPB1,RBM7,MPHOSPH6,EXOSC1,SNRNP70,ZCCHC9,EIF3G,DDRGK1,DIS3L,TLE1,AATF,FTL,UFL1,WDR3,C1D,ERG28,EXOSC4,SNAPC1,NUPR1,ILF2,UTP15,EXOSC3,EXOSC8,PAFAH1B1,TP53 |
| 9.439e-03 | -4.66 | EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit) | protein interactions | 2145 | 84 | 34 | 19454 | 5460 |
SUGP1,ZMYND11,RBM15B,MECP2,BLVRA,EPOP,RBM27,CDK12,EZH1,PRMT5,MYBL2,EED,RBBP4,PRRC2A,DHX38,SNRNP27,WBP11,SAP30,EZH2,RP9,IK,CHMP1A,E2F6,SNIP1,DDX46,RBM23,RCCD1,ARGLU1,TRIM21,DHX16,RBBP7,PHF1,POLDIP3,RIGI |
| 9.439e-03 | -4.66 | Mis12 (MIS12 kinetochore complex component) | protein interactions | 67139 | 84 | 34 | 19454 | 5460 |
FAM83B,RBM5,CBX5,NUF2,TTC9C,TRIM29,TYW3,CTNNB1,TPM3,DSN1,SUGP1,NDC80,CEP85,AKAP8L,TRAPPC4,ZBTB38,CALU,MECP2,GCC1,DNAJC10,TNFAIP1,RNF10,NT5C3A,UTP23,GALNT2,MSL2,HNRNPF,SEC22A,AKR7A2,SPC24,GNB1L,CBX3,GOLGA5,ARPC3 |
| 9.483e-03 | -4.66 | YIPF6 (Yip1 domain family member 6) | protein interactions | 286451 | 114 | 44 | 19454 | 5460 |
TMEM31,TMEM14B,TP53,CCDC47,SLC7A14,GJB1,LPAR2,BSCL2,TMEM11,AQP2,PDZK1IP1,SLC38A7,TMEM237,CRB3,LY6G6C,SSMEM1,TCTA,CLN8,MFSD5,HSD17B11,JKAMP,STOM,GPR35,LMNA,ATP6V0E1,LPAR1,SLC7A1,TMX2,VIPR1,FCER1G,CGRRF1,TMEM106C,MFSD14B,SCN3B,RHCG,REEP4,TVP23B,MMD,EFNA5,LRRC3B,SLC7A8,ELOVL4,SLC1A1,RETREG3 |
| 9.483e-03 | -4.66 | MKLN1 (muskelin 1) | protein interactions | 4289 | 114 | 44 | 19454 | 5460 |
GGH,MYC,ZMYND19,MRM2,YPEL5,HTRA2,UBE2H,VIRMA,LDHA,HPF1,BMP1,RPA2,MMADHC,RMND5B,DVL2,GID4,GID8,RANBP10,NDUFS2,GREM2,INSYN1,HDAC6,SPON1,DDX50,ARMC8,TCEAL9,MRPL18,LILRB4,MALSU1,EGLN3,ZBTB2,HNRNPL,EMILIN3,SOX2,JPH4,LY6H,HBP1,AAMP,PNMA2,ADAMTS1,NDUFS6,MKLN1,MAEA,LECT2 |
| 9.510e-03 | -4.66 | positive regulation of epithelial cell proliferation involved in wound healing | biological process | GO:0060054 | 10 | 7 | 18204 | 5365 |
B4GALT1,LACRT,JAML,FGF10,ODAM,WNT7A,CLDN1 |
| 9.510e-03 | -4.66 | regulation of cell chemotaxis to fibroblast growth factor | biological process | GO:1904847 | 10 | 7 | 18204 | 5365 |
CXCL13,FGF16,MIR149,MIR16-1,MIR424,FGF1,MIR15A |
| 9.510e-03 | -4.66 | regulation of fibroblast growth factor production | biological process | GO:0090270 | 10 | 7 | 18204 | 5365 |
RGCC,ROCK2,AIF1,MIR152,FGFR1,MIR205,MIR195 |
| 9.510e-03 | -4.66 | response to selenium ion | biological process | GO:0010269 | 10 | 7 | 18204 | 5365 |
GPX1,TXNRD2,SOD2,SELENOW,SELENOV,SELENOM,SELENOP |
| 9.510e-03 | -4.66 | peptidyl-histidine modification | biological process | GO:0018202 | 10 | 7 | 18204 | 5365 |
DPH6,DNAJC24,SETD3,METTL18,DPH3,NME2,DPH5 |
| 9.510e-03 | -4.66 | response to interleukin-2 | biological process | GO:0070669 | 10 | 7 | 18204 | 5365 |
IL2,JAK1,IL2RG,CITED1,STAT5A,IL2RA,IL2RB |
| 9.510e-03 | -4.66 | regulation of myofibroblast differentiation | biological process | GO:1904760 | 10 | 7 | 18204 | 5365 |
MIR9-1,RB1,MIR98,TP53INP1,MIR21,PDCD4,FOSL2 |
| 9.510e-03 | -4.66 | cellular response to cocaine | biological process | GO:0071314 | 10 | 7 | 18204 | 5365 |
COMT,SLC1A2,CRHBP,SLC1A1,SLC1A3,PPP1R1B,CCNA2 |
| 9.510e-03 | -4.66 | box C/D snoRNP assembly | biological process | GO:0000492 | 10 | 7 | 18204 | 5365 |
ZNHIT3,NOPCHAP1,TAF9,PIH1D1,RUVBL1,ZNHIT6,RUVBL2 |
| 9.510e-03 | -4.66 | regulation of voltage-gated sodium channel activity | biological process | GO:1905150 | 10 | 7 | 18204 | 5365 |
FGF12,SLMAP,FGF13,MIR192,MIR24-1,MIR448,SCN1B |
| 9.510e-03 | -4.66 | regulation of epithelial cell proliferation involved in prostate gland development | biological process | GO:0060768 | 10 | 7 | 18204 | 5365 |
CDKN1B,EAF2,NKX3-1,CTNNB1,AR,WDR77,STK11 |
| 9.510e-03 | -4.66 | cellular response to testosterone stimulus | biological process | GO:0071394 | 10 | 7 | 18204 | 5365 |
RWDD1,IGF1R,ELK1,ROCK2,MSN,SPP1,AR |
| 9.510e-03 | -4.66 | positive regulation of establishment of protein localization to telomere | biological process | GO:1904851 | 10 | 7 | 18204 | 5365 |
WRAP53,CCT8,CCT7,CCT5,CCT2,TCP1,DKC1 |
| 9.512e-03 | -4.66 | KIAA0319L (KIAA0319 like) | protein interactions | 79932 | 87 | 35 | 19454 | 5460 |
LGALS8,LACRT,LAMTOR1,RHOG,ATP1B1,LRRTM1,RAB5C,LAMP2,RAB2A,VIRMA,STX6,LGALS3,SIAH1,ARF6,MSN,CD4,RAC2,GJA1,NRSN1,ARL10,ARF1,HRAS,EPO,RAB4A,HSPA13,TFRC,CCL3,BET1,TOP3B,GINM1,PI15,ARF4,ST8SIA4,CLEC12B,KRAS |
| 9.513e-03 | -4.66 | RHOV (ras homolog family member V) | protein interactions | 171177 | 242 | 85 | 19454 | 5460 |
VAMP3,RPS12,MACROH2A1,GANAB,FAM83B,YES1,ZNF622,TMOD3,CEP97,MAD2L1,SH3BP4,FERMT2,PKP4,SLC25A1,MRPL16,DEPDC1B,MAP3K21,PSMD1,DNAJC10,MYO6,BLVRA,LAMTOR1,ILK,SLC7A11,EPHA2,SLC38A1,XPOT,ARHGEF6,RAB9A,TXNL1,YKT6,SLC7A1,CDC42EP4,ITGAV,DAAM1,NOTCH2,MYL12B,SNRPN,SPTBN1,ETF1,CDC42,STOM,PICALM,SLC12A2,JUP,PAK2,GIT2,STT3A,WDR6,HACD3,SLC39A10,XPO5,SPTAN1,CAV1,PPIA,SLC38A2,PRDX1,PIK3R1,TPM3,PPFIBP1,OLR1,NCK1,SLC2A1,SLITRK5,DLG1,TOP2B,SFXN1,SNAP23,MYO1B,CSE1L,SRPRB,WASL,SSRP1,PRPS1,FLOT1,PAK6,PSMD12,SLC6A8,CTNND1,RPS13,ARHGAP12,PCDH17,BMPR2,TFRC,RPN1 |
| 9.518e-03 | -4.65 | nucleus | cellular component | GO:0005634 | 7993 | 2396 | 19108 | 5553 |
UFL1,VDAC1,SH3GLB2,RAG1,ERH,TAF11,ATRAID,NOPCHAP1,IRF2BPL,AZGP1,NGDN,UBE2A,ACTL6B,PSMB10,DNAJB2,TSEN54,EED,IDH3B,INSM2,EEIG1,SCG5,RUNX1,MLH3,ZMAT3,RNASEL,UAP1,PPP1R1B,DDX46,FAM50B,PKIG,PCBP4,RIOX2,PRKCE,BACH1,KDM2A,MAFG,OAZ2,RANGRF,TNFAIP8L2,ZGLP1,SP1,FTH1,LPXN,SPIN3,AZIN2,SURF2,IRF6,BICD2,UBE2F,TSN,NDUFB6,POLR2L,WWP1,MAGEB1,SNRK,PAX6,PEX3,HNRNPH3,SLC25A31,PEA15,OAS1,RBM15B,COIL,RGS2,ZNF574,PAXX,MRPL23,GNL1,DGCR8,SRP54,NOL4,RPL7,NHEJ1,STK11,RAB2A,MLLT6,UNC45A,MAGEB10,MRPL52,RAF1,CIPC,APOBEC3F,RNF146,SPATA4,CFAP68,UCHL3,ING1,PRKACB,PNMA1,NME2,PLPP6,THUMPD1,FBXO25,MX2,ZNF511,SMAD4,NACC2,APOBEC3C,POU5F1,VPS4B,SPOPL,FGF12,PPIB,HUWE1,CDC40,NOP16,MED9,SNAI3,INTS6L,OAZ3,SNRPB,JMJD8,ANAPC13,CSNK2A1,PSMA6,UBL5,ZRANB2,ZBTB17,ZNHIT3,HMGN4,TXN,MAPKAPK5,MAP1S,ST6GALNAC3,VEZT,ABCG2,MAPKAPK3,MOB3B,ATP5PO,TRIM26,TNFAIP1,TUBB4B,NCK1,NOP58,HPGDS,H2BW1,ZNF581,HACD3,PTGES3,SART3,NUBP2,DNAJC1,CDC16,POLR2G,GTF2I,MAGED4B,OIP5,LITAF,SNRNP27,DUSP18,CD38,EIF2S2,CSTF3,TOX4,NPM3,POLD2,ZSCAN1,RANBP1,CSNK2B,DNAJC27,SPHK2,PSMB9,NFKB1,USP2,TGIF2,HSPA8,KLF1,PELI1,FEM1B,CPT2,ARL2BP,FTSJ1,MAPK4,CLIC2,HNRNPC,WDR5B,HPF1,WDR3,HMX1,SH3BGRL,PELP1,SPRYD4,NF2,FAF1,OPTN,SSBP2,SMARCD3,FBXO32,KLF12,FLOT1,RFX4,H2BC1,RDM1,KRT7,TSG101,PPP2R5E,TDP1,UTP6,ZFAND2A,RPS28,BRMS1,RPL6,PREP,GAMT,SLC13A5,FABP4,NUP37,DDX50,B9D2,ALKBH3,USP16,PTGES,KCTD15,FAM98A,MAP2K6,HNRNPH2,ROCK2,BRD3,BATF,H2BC14,PRKRA,ZNHIT1,SOX9,CAVIN2,PSMB5,ZMPSTE24,ZMYM3,NHP2,ARPP19,DDX42,NEO1,TMEM176B,POLDIP3,STC1,CDK4,FGFR1,OAT,RTN4,PIK3R1,RTRAF,PPIA,SPATA2,RSPH1,CHCHD2,PCGF2,MTF1,HINT3,SNRPB2,GNAZ,EXD2,TAB1,S100A8,METTL18,NLRP6,MSANTD4,RIT2,SMAD3,BUD31,CDKN3,APEX1,PSMD3,C9orf72,SMN1,POMP,UBP1,FAM20B,ARB2A,TENT2,NLRP1,SDHAF2,MLLT11,SESN3,PCSK2,GTF2F2,SHOC1,TADA1,PRR19,RPLP0,PIP4P1,SLC30A5,GTF2H4,FAS,NR1H2,ELF1,PRICKLE2,MKLN1,BABAM1,CFTR,ATF4,APPBP2,CUL3,CSE1L,SMARCB1,RFC3,RMND5B,CALR,PPAN,TSPAN15,ACADS,SLC25A42,NOTCH2,ING5,LYAR,RASL11A,NOP53,UBE2M,MAX,SPRED1,PSMA1,TSR2,BHLHA9,CSNK1A1,ITK,EMX1,KLHL22,WWP2,CAV2,CPSF1,IER2,GINS3,NUP35,KPNA2,BTG2,USP8,MTA3,TRMT112,IKBKB,ZNF518B,COPS4,NAA16,VDR,LLPH,RPL19,SNAPC1,ZHX3,NAIF1,SUPT3H,STAMBP,ANXA4,MRFAP1,MCRIP2,PSME1,ELP6,SNRNP48,LSM3,TSPYL4,GSTM3,PTHLH,DEDD,CDK12,IMP3,HSBP1,MSL2,SP4,ADNP,ZNF576,CLK4,MINDY3,RNF40,IP6K1,ANKRD10,ACTR2,DPH3,DVL2,SERPINA3,TP53INP1,MX1,ADH1B,SLC25A11,HDAC6,TCEA2,PHF7,MZT2B,FAM107A,MED21,DPEP1,NEUROG2,NR1I2,TRIM21,MTG1,KLK6,LMO4,LYPLA2,SRSF12,PRKAG1,GINS4,TOPORS,NOS1AP,NPR2,SNX20,FKBP4,SH3BP4,MECR,SF3B6,BAHD1,RNF11,TRMT10B,ZNF330,CPNE2,NAP1L3,CARD19,MAGOHB,GABPB1,RNF208,COMMD9,PPIL3,SNRPD1,UBLCP1,SMG5,SYNCRIP,ZNF501,ORC5,CBLL1,PRELID1,HINT1,RALGAPA2,CRYGD,TCEAL9,TMOD1,CIRBP,CDKN1B,VGLL4,G2E3,NDUFAB1,MEF2B,LBX1,MOB3C,RBM23,EEF1E1,SHPRH,CHCHD1,GEMIN7,ZNF345,PRDX6,PPP1CB,PICALM,RRN3,PRRC2A,UPRT,PRMT2,ZBED4,PARP2,MAP3K14,CYC1,DCAF4,BAZ1B,SHMT1,POP7,TMEM38B,RPL10L,CETN2,SUMO3,CETN3,JUN,SSU72,LORICRIN,TENT4A,ATF3,TRIM32,RAD21,RBM27,UNC50,NCKIPSD,ZNF287,INPPL1,PSRC1,ESR2,RPP14,COPS5,MCM8,EID1,MID1IP1,APTX,LARP4B,DDX1,TMEM89,APOBEC3G,SRSF2,ZNF668,MCM6,H2AC25,HERC4,RBIS,JAK1,IRF2,DRD1,NOC4L,ELK1,PLCB1,RASL10A,ZBTB2,FABP5,PCLAF,RPL8,CFAP20,GNAI2,TFIP11,TRIM63,MFAP1,TCF23,CTNND1,DDX4,APEH,TOR1B,CENPP,CRY1,TNKS,DESI1,CRYAB,COX4I1,SSRP1,LEMD3,RPL26,SEC14L1,ZBTB42,MACO1,COMMD8,OTUD7B,IRF8,LAP3,AKAP17A,DYRK2,RSL24D1,SNRPG,EIF5B,TERB2,DUSP1,THOC2,HNRNPA1,DTD1,PCNA,SLC8A1,TTC4,DMAP1,LSM10,GLRX2,HIKESHI,NLE1,ALKBH2,OGG1,CFAP36,TSPAN5,BUB3,ZNF704,NKX3-1,DCAF11,MAK16,UTP15,TCIM,SERPINB6,ZNHIT6,FOXS1,LUC7L3,PIAS1,SLC7A14,DRAP1,RP9,WTAP,RPS27L,SRI,RAMAC,CELF6,DHX15,TMEM70,STUB1,OPRK1,TOR2A,THRAP3,PARM1,VMP1,SAP30L,PAK1IP1,TRIM11,TCEAL7,CDK7,INO80E,BCL6,SLX1A,RB1,EIF4EBP2,BRMS1L,TMEM97,DUSP6,SOBP,LGALS3,SLC35A2,RB1CC1,R3HDM4,PHAX,GRPEL1,EPOP,RPS13,SPRY1,ZCCHC9,DAG1,BRCA1,ZCRB1,ABHD5,SETD7,SS18,WDR11,SIGMAR1,ZCCHC17,ALOX5AP,PIWIL4,PRKCA,RBP2,NSMCE3,FOXJ3,GLUL,NIBAN2,PCGF6,DLG1,ZNF593,NUDT16,DROSHA,SOX2,CMAS,DCUN1D3,H1-3,TYMS,CHMP1A,H1-6,CTDSP1,H2AZ2,TMBIM6,MATR3,ZNF862,COPE,TERT,CDC73,FAM20C,SLC2A1,NCOA5,PSMC5,CMPK1,RPL12,DNAJB9,CCHCR1,KCNIP3,CRYM,PNMA3,POLE3,SNRNP70,UBE2V1,GABPA,PPP1R10,FAM169A,LIG3,RMDN3,AKT1,H1-10,CDK8,NAB1,CRHBP,ZNF397,GPRASP3,XAF1,ATP6V1A,TNIK,SCML2,NDN,FAM156A,SIVA1,PARD6A,STK24,DCAF5,PREPL,PLEKHA8,VPS72,COPS2,STX6,GSK3A,ZNF526,TAF9,PRKX,GTF2B,PLPPR1,TFCP2,SPACDR,H2AC4,PAK6,PPP2R5A,POGK,BCL9,BMPR2,DCK,SMARCA5,IL15,EEF1AKMT3,GRAP,TNPO3,MYG1,CCNI,YWHAZ,NFYB,ZBTB14,PARL,PDE2A,CAMK2N2,SQSTM1,AKIP1,PNMA2,FHL3,TRIM68,PPM1G,PHF21A,SURF6,RPL18,GADD45A,CREBZF,BPNT2,PPP2CB,SYNE4,LANCL2,SAMHD1,MTDH,ELK3,RPL10,TOLLIP,RPS23,ANKRA2,BRIX1,PIH1D1,INPP5K,CSTA,CENPW,MORF4L1,SLC25A1,AGO1,BCL2L1,MPHOSPH10,SLC11A2,HOXC4,NBN,ZNF592,MEAF6,RORB,CAMK1,NDUFB4,CDKN1A,BCL7C,DNASE1L1,RRAGA,FKRP,S100A10,CRABP2,ZNF688,MAGED2,IGFBP3,CTNNA2,DCUN1D5,NKAP,PSMD12,FOXA3,RBBP8,TEF,PHACTR1,LIMS2,LRWD1,DES,XPO1,DHRS4,LYPLA1,INTS12,OTX2,CMTR2,SRSF1,STN1,COMMD6,NFIL3,STX12,DYNC1I1,HNRNPK,STAT6,PRKCB,CDIP1,CRKL,PFKFB2,GRM1,CHCHD3,DAPK3,TGIF2LX,POLL,ENO1,VIRMA,CRADD,SNRPD3,BRAP,TMEM170A,ARFGEF1,GMNN,RCL1,DUSP9,RFC5,RPS10,PAAF1,HDAC3,KCNH1,PFDN4,UBA3,METTL22,STAT2,TMEM209,SEC13,ZNF805,LCMT1,MDFI,NDC80,SRC,EXOSC8,DDX23,LDHA,PPP5C,ZC4H2,ABHD14B,JAK2,NSA2,DTYMK,WDR12,SPMIP9,MAD2L1,KDM4B,XBP1,ARGLU1,PSMD7,PRR13,NFKBIA,RRAGB,EEF1G,SATB1,MT1X,SFRP4,CLIP3,MTA2,SUV39H1,HECTD1,STRADB,POLB,FAM118B,RARS1,NTMT1,DFFA,PDE8A,KDM1A,COPS7B,DMTF1,MKKS,TNFAIP8L3,DRGX,APOBEC3D,LMNA,NKX3-2,SIN3A,RNF10,FABP7,TBC1D1,GNAI3,SCAND1,METTL21A,ANAPC2,ZNF322,ANAPC4,BTF3,FASLG,UCKL1,NAP1L5,GTF2A2,BOLA2B,PDE4B,STPG4,CHRAC1,AGPAT5,CLK1,HNRNPF,CENPL,USP46,SSBP3,TRIM37,MRPL10,PRM1,GNB1L,ARL4A,MIS12,FBXL3,CREBBP,ID1,TRMT5,MSMB,MIR9-1,CD1E,EXOSC4,TRIM45,TCEAL1,RPS12,WDR77,RPL27A,ALYREF,GGH,PPID,ZFP1,MOV10,SMAD5,VCPIP1,ORC6,PSMB7,ACOT13,CDK2AP2,SLC35F6,CSTF2T,RPAP2,HP1BP3,ANP32B,RPS24,CASK,TRIM5,HSPB2,POLR3F,PIP4K2C,NUP107,DNLZ,AIFM1,NHERF1,HELT,URM1,NAE1,ECD,PRSS37,MIDEAS,CGGBP1,USP13,NUDT5,UBE2B,VDAC2,CBFB,FANCG,IDH3A,ESS2,PRKAB1,ARMC8,UBN1,ACTL6A,NCDN,GNPDA2,BAALC,RNF20,CEBPE,MARS1,TCEAL8,NSFL1C,EZH1,TRAF2,HINFP,ATP5PB,GLRX,CPLX2,FOXP2,RPS16,NUPR1,DHX16,PCGF3,NDUFAF6,ZBTB25,H2BC12,CCDC92,CATIP,IVNS1ABP,OAZ1,SAP18,IL2RG,CITED1,RAD1,NOSIP,USP3,NT5C3A,PSMA3,POLDIP2,SLC52A3,ARL6IP6,MFAP3L,PABPC1L,CSNK1E,SUGP1,HEXIM2,SNAPC5,DDX39A,CCDC69,S100B,VRTN,IZUMO4,MACROH2A2,SSX2IP,FGD2,CDC5L,SASH3,NOB1,ETF1,PNO1,AKT3,CCNQ,GADD45B,RNF34,ANAPC16,NFE2L1,LHX2,SETD9,IRAK1BP1,AKT2,KIF2A,NRDE2,EAF2,WDR55,NUP42,CKS1B,S100PBP,TXNRD3,RPF2,TOP2B,MRM2,RBM12,ZNF740,CDK20,MT1E,IGF2BP1,RFXAP,ATP5F1B,FAU,TOR1AIP2,IFRD2,ZNF174,LSM6,ZNF655,RPL10A,UMPS,STK4,HSP90B1,DTWD1,ENC1,SMDT1,SDHB,CCNY,SNRNP40,KCTD10,CSNK1G3,NOL7,SF3A1,PPP3CA,PTPN22,PSMA5,MMP14,TRIM15,PSEN1,KHDC4,SMYD3,AGAP2,PAK5,GRSF1,MAB21L1,RBBP4,POLR3GL,FEN1,NUCKS1,EGLN2,GID8,PARP11,DUSP3,MSX1,DICER1,CPNE1,KCNJ11,UGDH,SENP5,HMX2,SPATS2L,EWSR1,CCS,H2AX,ZYX,AR,POLA2,GJA1,RBM17,CD2AP,YAE1,ZNF575,MRPS9,EXOSC1,MSRB1,CTNNBIP1,TP53TG5,PRSS23,SNAI2,SERPINB9,RP2,TRAPPC2L,UBE2E3,KIT,RPP21,SIAH1,POU3F4,WBP11,YAF2,ZNF664,WEE2,GTF2E2,TOB2,ZMAT5,PLAAT3,TNNI3K,NR2E1,MCPH1,TIA1,CDK5RAP3,UFD1,RBM34,RPL7L1,TEX12,CDKN2C,HSPB6,PLSCR1,MAGOH,TMEM147,CDK5,TASL,SMNDC1,DYNLL1,SUPT4H1,PSMB3,TRMT6,CFL1,HAND2,CFAP298,SLC39A9,VPS54,SDHAF1,UBA52,CFDP1,TCEANC2,ZNF362,PTP4A3,DCTN4,OLFM2,NEK9,ADRB2,NMI,RSRC1,EIF3K,DDX5,NFE2,NUF2,CCDC86,ZMAT2,NMRAL1,ZBTB6,MPG,CEP19,ADRA1A,ERCC3,NUDT3,HCFC1R1,DNTT,PNRC1,TIMMDC1,WRAP53,SPR,CLU,HNRNPA2B1,ACTN4,MECP2,ASPA,TDRP,POU1F1,MAGEH1,DR1,H2AB1,VRK1,REXO2,ZBTB5,HEY2,TMEM115,RPL7A,GRAP2,RBFOX2,TMX4,SNIP1,MCM4,IRF4,PREB,RPS3,DCTPP1,MNS1,STK3,SEPHS1,RCBTB1,DSN1,ELAVL4,FOLR1,PKP4,POLR2C,SF3B5,SMCHD1,MTCH2,MT1M,JUP,BIRC5,ZNF609,YIPF5,AKR1B1,MNAT1,EIF4A3,THOC1,PSMD10,ZNF267,CTSK,KLF3,CXXC5,HAPSTR1,GJC1,CREB3L4,SIRT7,HDHD3,TRIM52,USP30,CCND3,SOX14,EIF3E,DKC1,DCP2,MACROD1,RNASEH2C,ABHD16B,DYNLT3,TFDP2,NAA50,RWDD3,STAT5A,SESN2,RFXANK,CDK1,TRIM24,FZR1,PSMD6,MTAP,SNAPC3,ZNF304,EGR2,RPS29,RNF126,GIT2,IFI35,CLIC4,DMPK,KLC2,ZNF200,SMARCE1,SAP30,SSBP1,FBP1,CGRRF1,ATPAF2,MPIG6B,PPM1D,DPPA2,THOC3,CD63,TXNL1,PPT1,COMMD3,TCEA1,LSM8,PIK3R2,RPL17,DRG2,POLR3H,ANAPC15,RALYL,XPO5,CDCA7L,AP5S1,S100A11,CHMP5,RIMOC1,STAC3,PRPF4,IMP4,RPL35,SPMIP5,NUP62,IRF1,PPIG,STK16,SOD1,INPP4A,YBEY,ZNF319,FOXP3,MARVELD1,DGCR6L,ZMYND11,ADIG,RNF8,FOXC2,RHEB,GLO1,RBMX2,NICN1,MYT1L,RPS9,FAAP100,CACYBP,MED29,VSTM2A,MED4,PLEKHO1,LMO3,MRPL40,SNRPN,UBE2H,TNFSF13,KRT8,MSH6,NME1,MED30,CYFIP2,MAGEC2,MXI1,PABPC5,TAF2,PFDN5,CMKLR2,PDCD4,BECN1,NUDT4,CYGB,ODAM,API5,WBP2,MGST3,THAP2,FBXO11,TBK1,ZBTB18,SNRPD2,UBE2D3,MED27,MCMBP,SPMIP6,GNAQ,SAV1,TCOF1,RPS14,HENMT1,ZBTB26,SUFU,FAM76B,RING1,PITPNA,PSPC1,APOBEC3B,RPA2,RNF14,MTX2,MED23,TESPA1,SGF29,GPX4,MT2A,SPC24,EGR1,DBR1,ZNF32,SNAPC2,RGN,APEX2,CPSF4,ISX,CTDSP2,VPS4A,LIMD2,CCDC85B,MOSPD1,POLR2F,CSRNP1,E2F4,PDE9A,LSM2,IQSEC1,FBXO7,DENND2D,SRPK2,TRIP4,RPL9,IRF7,LDB2,UTP25,MCL1,SRSF4,SNAP23,CXXC1,CCNH,NCBP2,TXNRD1,CTNNB1,DUSP10,RNF187,CENPM,ASCC1,MORC4,NR4A2,DUSP21,CTDSPL2,RRM1,H2AC13,VPS26C,RPL15,PTPN5,RPS20,DNPH1,WDR6,GEMIN8,H3C1,UBASH3B,ISCU,OSBPL8,TRIM8,ASRGL1,SGMS1,HMGA1,NUDT12,PMP2,RGS6,KLHL15,COPS7A,KLHL7,SLA2,SUMO2,RAC2,MED13L,TP53,RPL23A,HLF,CTSC,TPT1,RBBP7,E2F6,NUP50,ZNF507,ANKRD49,PHC1,ZBTB38,BTBD10,TCF21,PAK2,NUDT1,PPIH,EIF2S1,UBE2I,PYDC2,TSSC4,TRUB1,PIP5K1A,MBD5,SURF4,DHX9,NIF3L1,OSGEP,POLR1D,ELP3,CNOT6L,RPA3,SETD4,NDUFAF3,ANP32A,TMSB4X,SKIC8,MAD2L1BP,GPRASP2,PPP2R1A,HAX1,SSNA1,ARMCX3,TRIM6,CCDC106,FBXL19,CIBAR1,PLAA,TENT5C,ZNF692,NR1I3,GLE1,CTBP1,TECR,NDUFS3,PSMB11,OTULINL,APBB3,HELLS,SDR16C5,ZC3H14,PRMT5,CLP1,CDK5R1,KLF4,RPS15,HMGB1,TAF7,DTWD2,RSBN1L,MGST2,BARX2,PDHA1,DDRGK1,EIF4E,RHOB,JPT2,RANBP6,SRFBP1,ZCCHC7,EIF1AD,DTL,IK,ADRM1,CREB1,CINP,GAPDH,MND1,USP39,ILF2,IDE,RRP7A,TAPT1,EIF3G,IRF2BP1,G3BP1,TAF5L,RPL27,AZIN1,SRSF7,CRLF3,FGF1,IER3,PTGDS,GADD45G,TRAF7,PSME2,CHMP4C,SNX10,ZC3H11A,MAEL,CSRNP3,THAP1,SRSF8,FAM193B,MRPS18B,MED11,RIOK2,GPBP1L1,SGTA,CNPPD1,YPEL4,POLR1H,ARHGAP15,FHIT,TMEM190,SMUG1,RPS26,FAM222B,BNIP3L,PPM1M,BOLA3,PLSCR3,PYCARD,MEF2C,TRA2A,NUFIP2,FBXO3,FOXP1,KIN,HOXD12,ZCCHC12,SKAP2,PAFAH1B2,SRP14,CCNB1,TRAF6,PDIA3,PQBP1,TRMT1L,RAPGEF5,EIF2AK2,DXO,ALG2,ZKSCAN1,RPL37A,TRIM27,PKIA,TNFAIP8,IKZF2,RAB5A,STK38,TIMM17A,PKIB,SSH3,SSBP4,ELOF1,NEK7,HYAL2,NLRP3,MPHOSPH6,DYRK1B,NGRN,DET1,TRIM23,UBE2L3,TERC,KANSL3,SMAD2,SCNM1,ZNF343,PPWD1,NOVA1,FBP2,TAGLN3,HIRA,PSMC3,LSM4,H2AC7,BAG3,LINC02914,PPARA,DHX38,MYBL2,AIPL1,PPP1R26,NAA30,UTP23,OVOL1,PSMB1,LBR,MBD3,EGLN3,APOBEC3H,NKX6-2,RPSA,UQCRC2,NEK2,JAML,NAA35,CCAR2,RBM42,JADE1,TMEM33,LIPA,DLX1,MRPL36,TMEM168,SUPT7L,MIF,RETREG1,HNF1B,CDC7,SRARP,JUNB,PPP1CC,ATOSB,NAA15,CACNB4,TMUB1,PSMB4,KARS1,LRIF1,POLD4,TNKS2,IRAK4,RTF2,TOP3B,PML,PSEN2,HAS3,TOR3A,SMAD9,FERMT2,CBX3,THOC6,RFX5,ZNF687,FOS,GSTP1,ZSCAN25,HEXIM1,KRR1,TOPBP1,RDH10,SPRN,PHB2,ARPC3,ZNF787,AATF,AMT,PWP2,HNRNPAB,MAPK10,RBFOX3,IRF3,ARPC2,GTF3C3,RPL3,PAFAH1B1,SAP30BP,PHF23,NCAPG2,POLR2B,ARMC7,HADH,BIRC2,TMA16,ASPM,SFN,SETD5,BEND6,ZNF177,CBR3,SP2,CRBN,CRYBA1,NFKBIL1,H2BC17,FTSJ3,OSR2,RXRG,CSRP1,PEBP1,S100A6,HYPK,PSMD1,PSMD4,FGF13,CPSF2,TRMT61A,RPS4X,HSH2D,MAD2L2,ATP5F1A,UFM1,UBE3A,PSMA2,DUSP26,SNRPA1,GIMAP2,POLR3B,IPO8,PRDX3,DRG1,TNRC6C,NONO,RADX,RSAD2,CDC23,RFC2,MYORG,ACSS2,INO80C,NXT1,TRIM22,CUL2,EDF1,FRMD8,ZNF22,NRM,MDC1,HOXB8,BCL10,EXOSC3,GTF2F1,PHF13,CEBPG,PRNP,REEP6,NEDD8,PABPC1,RUVBL1,TUBB,RNF115,FBXW11,TLDC2,CHTOP,C2CD2,KLF10,NFE2L2,ZNF451,EEF1A1,TIGD7,CDKN2D,ZFP64,OLA1,CDKL2,TMEM179B,RBM3,MXD1,SERTAD3,RANBP10,POLE4,CDC26,YTHDF2,ING2,CCAR1,CDKN2AIP,MYO6,EYA3,ZNF770,FAM53B,AKAP8L,AGER,FOXN2,MSX2,RFC4,PTPN4,GON7,VXN,BRD9,ID4,HSP90AA1,CCIN,CTNNBL1,RPS11,MRPS26,TWIST2,PRPF19,FBXO22,MED17,BAP1,UBE2E2,SLC39A7,SNRPE,HFE,PIWIL2,EHBP1,CEP85,MAP2K3,BEX3,WDR83,CHID1,NTAQ1,EI24,ELOC,ISG15,OLR1,CHMP1B,MEIOB,ACHE,ZBTB16,RLIM,SIAH2,RUVBL2,H2BC11,FNDC8,EIF5A2,CCR2,SYVN1,PROX1,CST11,SEPTIN7,TNPO2,RPP25L,FLCN,USP15,PSMB6,SPOP,UBB,ZSWIM7,ZMYM6,ANAPC11,CWC15,LDOC1,PTPN11,IL15RA,MLF2,EMP2,CHAMP1,MLF1,MIOS,TGFB1I1,CCT8,TAF10,DPY30,SMAD1,PHF1,MTMR2,PYM1,ABHD17A,PAPOLA,RPS27A,BTG1,LCORL,FAM53C,BTG3,ERRFI1,PPP1R11,PGR,ATF1,NFYA,LSM5,ZNF473,ZNF821,PTEN,ANKRD6,CLPX,PPP1R12A,CDK17,TAB2,STOX2,CIMIP2C,TRNP1,PPME1,RPS2,PLEKHF1,AFTPH,SHOC2,MAP2K1,HNRNPD,GTF2H2,RETSAT,ZMYM2,ZNF263,UBXN2B,TOP1,RAD23B,RPL4,CRYGB,ZC3H7A,ZNF622,EIF2B5,NEUROD6,RERG,VTA1,STRBP,IKZF5,NDUFB5,METTL14,ALB,KBTBD6,HDAC5,GTF3C4,EID2,EMX2,DNAJB4,ISG20,TSNAX,NQO1,MT1A,WDR37,ADK,TEX19,FCF1,UHMK1,PDCD5,CDK9,NAB2,ACACA,TESK2,MAF1,MGMT,PLAGL1,GPC4,SUMO1,POMT2,SF3B1,CHMP2A,VGLL2,ZNF326,CHST2,MCOLN1,EP300,YPEL5,UBE2N,SGMS2,SERPINB10,HTRA2,STX1A,CSTB,HNRNPL,RPS6KA4,ABITRAM,CNOT2,PSMC4,STAP1,BUD23,ZNF513,RBM22,FRA10AC1,ZBTB39,NDUFS2,HILPDA,PKNOX1,NUP153,EXTL2,PRDM4,PPM1B,EMG1,HOXB1,CDAN1,HRAS,PDHB,HBP1,CHMP2B,RPS5,KLK3,SYCE3,NUDT9,PADI2,RPS17,TIMP3,INTS10,ZNF652,NXT2,PSKH1,PEG10,RBM18,ZNF250,HCLS1,CBX5,RAN,PDE7A,FKTN,POLR2D,CREB3,KLF9,RCHY1,FXR2,ENY2,BCL7B,SYK,CWF19L1,LDB1,INPP5E,SUPT5H,CNOT6,BANF1,TRA2B,BCCIP,BAX,ZC3H15,TXNL4A,TESK1,CNOT7,HNRNPA0,SNRPA,UBE2V2,KMT5B,MCM3,HSPB8,LMNB1,GTDC1,SWAP70,ATP6V1D,ELK4,USP5,PTP4A2,TOX,RNF7,DNTTIP1,RBM38,MYCT1,TRIB1,PRPF31,COP1,OCRL,CRISP1,CFL2,HMG20A,DNAJB6,COX10,CAPG,H2AC6,RASD1,MITF,PRDX1,SF3B4,UGP2,ZNF175,XPOT,PMM2,TNFAIP3,METTL6,CCDC22,HSPA13,SETD3,POLR2I,C1D,APOBEC3A,LYZL4,TPPP,CCND1,JRKL,PCBD1,RBM41,TESC,ALKBH4,TUBA1A,SCML1,TRAF3IP2,RPAIN,ABCF1,GGPS1,FAHD1,TTI2,CHP1,RPP25,H1-5,RBBP9,BHLHE40,PPARG,PSMC1,CMTR1,IFRD1,ROGDI,RBMS2,MED10,UBE2D1,BOK,GFI1,PRKD3,FBXL4,TES,KPNA6,CCDC134,RPS7,PLA2G15,PRDX4,TMPO,MYRF,TADA3,PAGR1,AIP,H2AZ1,OARD1,RBM5,PSMD14,TRIM35,RPF1,ANKRD34B,UBL4A,DYRK1A,TSC22D3,CD274,SPTBN1,PPIL4,PRCC,DLST,MRTO4,RPRD1A,SMURF1,SMAP2,SOX21,EFNB1,MT3,GATAD1,DCTN3,ZNF189,PSMG2,FYTTD1,HDAC11,ZNF436,CSNK1A1L,HNMT,NOL12,PAPOLB,H1-1,FEM1C,GTF2A1,RPRD1B,PAX9,RERE,ZBTB45,NEUROD2,IL1A,ANXA7,EEF2,TFPT,IFI16,TP53INP2,FOXD3,COTL1,VEGFA,GOSR2,DNAJC7,NAA11,RMI2,UBE2S,GTF2IRD1,SUB1,HNRNPDL,CCDC174,FABP12,TUBG1,HCFC2,RMI1,MEF2A,DNAJC2,GPC1,FUNDC2,TEX264,CAMK2G,ZNF790,GCHFR,TSEN34,SERTAD2,PHB1,CD2,UBXN6,DDIT3,ADH1A,NSG1,DDX39B,FBXW7,RGS7BP,CIART,SLU7,CD2BP2,ISG20L2,EEF1B2,H2AJ,RNF113A,HARBI1,ADD1,CPEB1,CNDP2,ARL4D,ZNF7,MSN,CAPN2,CASC3,CNOT8,NR2F6,ZBTB33,RBM7,ATXN1L,PPP4C,ZNF280B,ZHX1,STXBP1,PTPMT1,PTTG1,NOP9,PSMA4,PRMT6,UQCC2,SOX3,MAEA,KPNA1,CGAS,MYC,SKP1,LDHAL6B,COMMD5,MACROH2A1,ZBED1,MEPCE,UBE2K,UPF3B,TRIM34,THAP7,POP5,DCUN1D1,SMC4,NKRF,SEMG2,MED31,RACGAP1,STAT1,MAT2B,SIX5,ETV6,RGS10,DCLRE1C,PFDN2,PMAIP1,CRTC2,NRBF2,TAF1D,TOR4A,GTF2E1,BRI3,SLC25A5,DNAJC8,IRF9,AQP3,SERTAD1,RPL22,PPP1R8,ZNF207,DAPK1,ACTB,ASF1A,ZNF24,TFEB,WDR20,UBIAD1,TAX1BP3,FOXI3,FERD3L,MYD88,PRPF18,P4HA2,PIR,ZNF596,FGF10,CDK6,PHF12,MRPS23,MORC2,TCF19,RPL13A,OSBP,H2AC1,TFE3,HSCB,RBPJ,PIWIL3,CCNF,CPTP,RBP5,RTCB,RGCC,ALKBH5,JPT1,HSPA5,PDLIM4,H2BC9,EIF2D,IFI27,GSKIP,DHRS7B,PSMB2,HR,DEK,SMU1,PACRG,SLC25A10,MED22,EZH2,LTO1,MAGEA4,FOXP4,XRCC5,SDCBP,DCAF16,IFIH1,LBH,E4F1,SRSF10,AIF1,FOSL2,ARL14EP,MTMR6,FUBP3,CAND1,TLE1,TREML1,GTF2H5,HSP90AB1,PRIM2,ELF5,CCNA2,EID2B,LACC1,NABP1,CBX7,WDR82,USP38,LMO2,CDC20,MIR214,CREBL2,SPINDOC,RPL23,NR0B1,EIF4EBP3,GCFC2,ARHGAP19,UBE2W,AURKAIP1,MTPN,PITHD1,NFKBIB,RPGRIP1L,HSPB1,ZNF671,MDM2,TIMM13,TULP3,PIWIL1,WASL,POLR1B,MYEF2,UQCC3 |
| 9.519e-03 | -4.65 | F-actin capping protein complex | cellular component | GO:0008290 | 8 | 6 | 19108 | 5553 |
MTPN,ADD1,ADD2,CAPZA1,CAPZA2,CAPG |
| 9.519e-03 | -4.65 | clathrin-sculpted gamma-aminobutyric acid transport vesicle | cellular component | GO:0061200 | 8 | 6 | 19108 | 5553 |
DNAJC5,RAB3A,VAMP2,HSPA8,SLC32A1,GAD2 |
| 9.519e-03 | -4.65 | proteasome core complex, alpha-subunit complex | cellular component | GO:0019773 | 8 | 6 | 19108 | 5553 |
PSMA5,PSMA2,PSMA4,PSMA6,PSMA3,PSMA1 |
| 9.519e-03 | -4.65 | clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane | cellular component | GO:0061202 | 8 | 6 | 19108 | 5553 |
RAB3A,DNAJC5,SLC32A1,HSPA8,VAMP2,GAD2 |
| 9.519e-03 | -4.65 | HFE-transferrin receptor complex | cellular component | GO:1990712 | 8 | 6 | 19108 | 5553 |
HFE,TFRC,BMPR1A,BMPR1B,TF,B2M |
| 9.519e-03 | -4.65 | heteromeric SMAD protein complex | cellular component | GO:0071144 | 8 | 6 | 19108 | 5553 |
SMAD3,SMAD2,SMAD1,SMAD4,SMAD5,SMAD9 |
| 9.532e-03 | -4.65 | KPNA1 (karyopherin subunit alpha 1) | protein interactions | 3836 | 332 | 113 | 19454 | 5460 |
TAF9,HDAC6,COPS5,CSNK2A1,CRADD,CAND1,MDM2,DKC1,NCBP2,CTDSPL2,H2AZ1,RAC2,CDK8,NUPR1,STRBP,MTA3,KBTBD4,CD2BP2,CTNNBL1,TSSC4,PAK1IP1,CSE1L,KPNA2,MEPCE,NOSIP,NKRF,SPOP,TADA3,UBE2H,CDKN2AIP,ALKBH5,TAF5L,SMARCA5,MORF4L1,SUB1,KPNA6,CPT2,GABPA,NOPCHAP1,CCNF,PHAX,TRIM27,RPA2,LMNA,SUPT7L,UBE2M,RAG1,CDC42,IL1RAP,MBD3,RPA3,BAP1,CDKN1B,BAZ1B,PRPF19,NOP58,HNRNPL,MEAF6,RHOH,LYAR,EGLN3,TRMT61A,MACROD1,CLK4,COPS2,SKA3,MTA2,RHOBTB1,ANP32A,GPT,TUBA1A,NUP153,TULP3,G3BP1,RUVBL1,CCAR1,ANP32B,RAD21,BCL7B,RUVBL2,SREK1IP1,FAS,LMNB1,RHOB,FBXW11,POLR1B,MYC,CUL3,HNRNPC,SMARCE1,PRPF31,STAT2,STAT1,RBBP4,ESR2,APEX1,ZNHIT6,VPS72,RAN,KCTD12,GTF2IRD1,ADNP,NUP62,RND2,SUPT3H,LMO4,UFL1,PHB2,COIL,SMARCD3,SF3B1,NUP50,RAMAC |
| 9.533e-03 | -4.65 | NSD3 (nuclear receptor binding SET domain protein 3) | protein interactions | 54904 | 111 | 43 | 19454 | 5460 |
PRNP,BRD9,CCDC71,RB1CC1,LSM3,BRD3,YWHAH,PPM1D,BCL7C,LAMTOR2,RIGI,H3C1,ASF1A,TRIM63,DHX9,RPL31,CBX3,MLLT6,TOP3B,CBX5,APEX1,VIRMA,ESR2,SNRNP40,TAX1BP1,MACROH2A1,UBE2I,ZNF330,ZBTB38,HOXC4,H1-1,LMNB1,MYC,AKT1,STAC3,CUL3,COIL,SOX3,TERT,NUP50,SLU7,SEPTIN6,LMNA |
| 9.533e-03 | -4.65 | CTNNA3 (catenin alpha 3) | protein interactions | 29119 | 111 | 43 | 19454 | 5460 |
CTNNBIP1,NDUFB7,PKP4,EPS8,FERD3L,INTS12,PNMA1,GCFC2,PARP2,CTNNA1,GNB1,ATP5F1B,TRIM54,FAM161A,QRSL1,JUP,VIP,DVL2,SERTAD2,GINS3,CDSN,CMAS,EID2B,OIP5,BTF3L4,CTNNB1,RELL1,MAP1S,NAB2,TXNRD3,PPARA,TPD52,PNMA5,FAM162A,EIF1AX,STMN2,TNNI1,DISC1,BLOC1S2,KATNAL1,CTNND1,PAX6,LASP1 |
| 9.540e-03 | -4.65 | MS4A4A (membrane spanning 4-domains A4A) | protein interactions | 51338 | 41 | 19 | 19454 | 5460 |
ATP6V0E1,TMUB2,SEC22A,XPO1,ACADSB,TMEM14B,XPOT,CMTM7,SLC25A11,PLP1,RPRM,RUSF1,TMX3,XPO5,CSE1L,CAND1,CHP1,SERTM1,ILVBL |
| 9.540e-03 | -4.65 | NPEPL1 (aminopeptidase like 1) | protein interactions | 79716 | 41 | 19 | 19454 | 5460 |
MDFI,CAP2,HMBS,TPT1,GBE1,XPO1,TFCP2,TFRC,NIF3L1,FKBP4,CCDC25,OPTN,RB1,STAT1,MCMBP,SUMO2,PPAT,APEX1,ESR2 |
| 9.540e-03 | -4.65 | TIMM17B (translocase of inner mitochondrial membrane 17B) | protein interactions | 10245 | 41 | 19 | 19454 | 5460 |
PARL,DUSP19,TOMM20,DUSP21,EGLN3,PHB2,TRIM63,RMDN3,COX4I1,DUSP6,SFXN1,LMBR1L,TIMM23,RHOG,DUSP22,APOO,FAF2,CREB3,CIDEB |
| 9.547e-03 | -4.65 | FRYL (FRY like transcription coactivator) | protein interactions | 285527 | 55 | 24 | 19454 | 5460 |
HOMER3,CCDC71,VIRMA,HOMER1,SLMAP,HNRNPL,YWHAG,YWHAH,SFN,BAK1,YWHAB,UBE2H,PDCD10,YWHAZ,SQSTM1,STK26,ABCF1,SIRT7,SLU7,UFL1,CDC42,PIP5K1A,TOP3B,DISC1 |
| 9.547e-03 | -4.65 | ETS2 (ETS proto-oncogene 2, transcription factor) | protein interactions | 2114 | 55 | 24 | 19454 | 5460 |
BRCA1,COP1,POU5F1,CREBBP,ZMYND11,XPO1,EGLN2,SRC,TWIST2,NFE2L2,PPME1,TP53,RPL15,DET1,GTF3C4,JUN,CLU,DAD1,FOS,DVL2,IMPACT,NDUFB5,EP300,EWSR1 |
| 9.547e-03 | -4.65 | ZNF410 (zinc finger protein 410) | protein interactions | 57862 | 55 | 24 | 19454 | 5460 |
CEP70,OSM,ZNF24,LMO2,IRAK1BP1,PPM1K,CSNK2B,PNMA1,RPRD1A,LRIF1,ABHD8,TRIM35,ZNF397,LMO4,NDUFAB1,TRAF2,LNX2,POLR2G,HAPSTR1,PICK1,DVL2,NOSIP,PAX6,SERTAD1 |
| 9.547e-03 | -4.65 | TXNRD2 (thioredoxin reductase 2) | protein interactions | 10587 | 55 | 24 | 19454 | 5460 |
PSMC3,CTBP1,CFTR,TXNRD1,TOP3B,PSEN1,OXCT1,TF,HSCB,KRAS,IDH1,AGA,OAT,CHCHD4,TADA3,DNAJC5,PMPCA,PPP1R3C,FERMT2,TXNDC12,TRIM29,AKR1B1,ENO2,ACOX1 |
| 9.547e-03 | -4.65 | GYPB (glycophorin B (MNS blood group)) | protein interactions | 2994 | 55 | 24 | 19454 | 5460 |
TCAF2,TNPO2,METTL15,SEC62,EIF2B3,BZW2,DHRS7B,TSPAN15,CPLX1,LPCAT3,FANCG,RHAG,DNM2,PWP2,SLC39A10,EIF2B2,REEP4,EIF2B5,LRRC8A,ARL6IP5,COG1,RANBP6,IP6K1,MAD2L2 |
| 9.547e-03 | -4.65 | SCIN (scinderin) | protein interactions | 85477 | 55 | 24 | 19454 | 5460 |
CDC42,GPAM,RPA2,TMOD1,GRXCR1,ACTR1B,FBXO30,CSK,ATG9A,XPO1,BCL7C,SLC30A5,BAG3,FKBP4,TMOD2,ACTA2,OCIAD2,FZR1,DAPK1,TMOD3,ACTB,TRMT61A,G6PD,ESR2 |
| 9.547e-03 | -4.65 | TVP23C (trans-golgi network vesicle protein 23 homolog C) | protein interactions | 201158 | 55 | 24 | 19454 | 5460 |
GPR17,CCR6,LMBR1L,CD63,SLC11A2,SLC1A1,HNRNPL,RANBP6,EIF2B5,TOR1AIP2,SLC22A8,BZW2,AQP3,RINT1,TSPAN15,VIPR1,LPAR2,SLC7A1,SLC7A14,SLC15A1,TACR3,TSPAN5,EDEM2,SLC5A6 |
| 9.566e-03 | -4.65 | RTN4IP1 (reticulon 4 interacting protein 1) | protein interactions | 84816 | 90 | 36 | 19454 | 5460 |
MRPL11,PPP1R8,TP53,WBP11,METTL15,PDHA1,HEXIM1,MTRES1,ZYX,HSPD1,PYM1,HINT2,GFM1,RTN4,COX8A,PDE12,ATP5F1D,FASTKD5,IMMP2L,CDC42EP4,AUH,MTRF1,GRSF1,MARCHF5,PMPCA,RHOG,BLVRA,ARFGAP3,TMEM70,PPTC7,TACO1,SSBP1,CCDC90B,GATD3,MRPL50,CNTROB |
| 9.566e-03 | -4.65 | SFSWAP (splicing factor SWAP) | protein interactions | 6433 | 90 | 36 | 19454 | 5460 |
EWSR1,NUP50,RPA3,CCAR1,PSMC1,DPM2,UFL1,ERLEC1,KRAS,RAF1,H2AJ,ATG16L1,HECTD1,TMEM14B,DLST,EZH1,RBM42,ESR2,SRPK2,NCKAP1,CAND1,IFI6,SNRNP40,YWHAH,PSMD1,MYC,RBM17,CFAP20,ZCCHC10,ZNF24,UQCR11,UBE2H,BRD3,ANKRD50,DDX23,SNRNP70 |
| 9.569e-03 | -4.65 | INPPL1 (inositol polyphosphate phosphatase like 1) | protein interactions | 3636 | 204 | 73 | 19454 | 5460 |
PSME1,SLC25A5,RIGI,ARF4,TICAM1,ACTN4,NECAP2,EEF1A1,TMSB10,MTCH2,TOP3B,ARFGAP1,TUBB4B,VPS33A,AKR1B1,CD4,HSP90AB1,LRRC61,LYAR,SUMO3,PRNP,INSYN1,XPO1,YWHAH,FCGR2B,CIAO3,MAPK4,PIK3R1,NQO1,CBL,SHC1,SMAD4,DDX5,PGK1,HSPA8,BANF1,UGDH,HSPA5,PIK3R2,EEF1G,GTF2I,BORCS6,POLR1D,CD2AP,ALKBH3,ATG16L1,STAT6,ACACA,TMEM184B,GSTP1,MET,RPLP0,UBASH3B,SLC1A1,GTF2A1,GSK3A,TUBA1B,TMSB4X,RAN,ENO1,GAB1,SRC,ESR2,TUBB,AKR1C2,STAT2,AR,PCCB,MLF2,MCM4,HNRNPC,MDH1,RHOB |
| 9.569e-03 | -4.65 | HAT1 (histone acetyltransferase 1) | protein interactions | 8520 | 204 | 73 | 19454 | 5460 |
CCNF,LMBR1L,UBN1,TUBA1B,AP2M1,RBBP4,VIRMA,MYC,CUL3,USP14,ST13,PIP4K2C,RPA3,BAP1,SNAPC1,HIRA,HELLS,HSPA8,EP300,RNF113A,TNFAIP1,HSCB,IRF7,STAU1,MBD3,HSPA5,BCL2A1,AZGP1,RPA2,RSAD2,CDAN1,LUC7L3,SIN3A,PHB1,MYBL2,GATAD1,FZR1,CCAR2,BRMS1L,SHPRH,EGLN3,KLK3,STK3,IFI16,DPY30,COPS5,DDRGK1,CSTA,EPOP,MSMB,YWHAB,TRIM21,UBE3A,SEMG2,COX8A,H3C1,RBBP7,LSM4,G3BP1,ASF1A,TTC4,PHF1,MTA3,E2F4,H2AX,MAP2K3,TULP3,SAP30,EZH2,CBX3,RIMOC1,MTA2,RHOBTB1 |
| 9.572e-03 | -4.65 | regulation of cell cycle phase transition | biological process | GO:1901987 | 457 | 158 | 18204 | 5365 |
RAB11A,RPA2,DUSP1,CCND3,ADAMTS1,FBXO31,TMOD3,SPC24,CDKN2C,FGF10,OVOL1,CRLF3,DDRGK1,ACTB,CCAR2,PROX1,PKIA,RPL26,CCNQ,HINFP,VPS4B,FBXW7,FEM1B,TOPBP1,NOP53,AKT1,NUF2,FAM107A,CDC7,SOX2,BCL7B,MIR495,RINT1,IK,RB1,ZNF655,PRMT2,TERT,CRADD,H2AX,CACNB4,CRY1,MIR16-1,DCUN1D3,PAGR1,CDK5RAP3,PRPF19,MACROH2A1,CDKN1A,ANAPC11,TTI2,PML,CDC5L,CCL2,MAD2L1,MIR29C,PTEN,NABP1,ATP2B4,DLG1,CDK4,CYP1A1,BCL7C,CDK7,MIR221,AIF1,CCND1,PSMG2,CTDSP1,PSME1,NAE1,MIR222,ACVR1,MIR214,CCNH,BUB3,RIOK2,MIR15A,TMEM14B,CDC20,FZR1,VPS4A,IER3,ANAPC4,TCIM,CDK2AP2,TP53,CDC16,ERCC3,UBE2E2,LCMT1,CDC23,ZNF207,MIR873,MDM2,DTL,BIRC5,ACTL6B,MIR133B,GNB1L,CTDSP2,SMARCE1,CDK6,JADE1,PTPN11,PHB2,MTA3,BTN2A2,MIR10A,KLF4,CDK1,RAD1,ACTL6A,EZH2,MIR29A,ANAPC15,BABAM1,TPRA1,MIR195,CDKN2D,MAD2L1BP,NDC80,SMARCB1,WNT10B,RRM1,FBXO7,MIR638,RBBP8,MIR137,SIN3A,RAD21,MNAT1,MEPCE,MAD2L2,RPS27L,PPP1R10,ECD,MIR519D,NBN,CCNB1,CDC73,PSME2,MLF1,MIR503,CHMP4C,UFL1,LSM10,BRCA1,RGCC,GPNMB,CDKN1B,MIR193A,CUL3,MIR208A,KLHL22,MDC1,SMARCD3,PLCB1 |
| 9.573e-03 | -4.65 | QRSL1 (glutaminyl-tRNA amidotransferase subunit QRSL1) | protein interactions | 55278 | 108 | 42 | 19454 | 5460 |
GPBP1L1,MTRES1,PDHA1,GDI2,METTL15,COQ8B,MRPL11,FASTKD5,IMMP2L,PSMA5,KRAS,HSCB,YTHDF1,HINT2,GFM1,COX8A,HSPD1,EXD2,SPECC1L,BCKDK,MRPS26,RIT1,RHOG,ANKRD49,SMAD4,TUFM,MTRF1,AUH,MTG2,CLPX,GRSF1,PMPCA,ZBTB2,CPT2,MED17,FAHD1,GATD3,KRT8,FAIM,SSBP1,TACO1,DOK4 |
| 9.577e-03 | -4.65 | MBLAC1 (metallo-beta-lactamase domain containing 1) | protein interactions | 255374 | 15 | 9 | 19454 | 5460 |
PRNP,AGR2,RHOH,VAC14,CLP1,FNDC8,TRAF2,DDX39A,NDUFAB1 |
| 9.577e-03 | -4.65 | SAMSN1 (SAM domain, SH3 domain and nuclear localization signals 1) | protein interactions | 64092 | 15 | 9 | 19454 | 5460 |
SAP30,YWHAH,YWHAG,SFN,FASLG,HRAS,YWHAB,YWHAZ,KRAS |
| 9.577e-03 | -4.65 | DOP1A (DOP1 leucine zipper like protein A) | protein interactions | 23033 | 15 | 9 | 19454 | 5460 |
VIRMA,VAPB,HNRNPL,NPTN,YWHAH,YWHAG,SFN,GPR17,RAB11A |
| 9.577e-03 | -4.65 | RGL1 (ral guanine nucleotide dissociation stimulator like 1) | protein interactions | 23179 | 15 | 9 | 19454 | 5460 |
HRAS,RIT2,RAP1A,RAP1B,RRAS2,RAP2A,TULP3,RIT1,VIRMA |
| 9.577e-03 | -4.65 | GPA33 (glycoprotein A33) | protein interactions | 10223 | 15 | 9 | 19454 | 5460 |
KLHL22,EMP3,GPX4,CTDSP2,ENTPD3,NRSN1,HNRNPL,SMCO4,NSG1 |
| 9.577e-03 | -4.65 | DDTL (D-dopachrome tautomerase like) | protein interactions | 100037417 | 15 | 9 | 19454 | 5460 |
MDH1,PFDN6,TRIM24,MTPN,XPO1,RPS28,CSTB,CCNF,PSME2 |
| 9.577e-03 | -4.65 | TIAM2 (TIAM Rac1 associated GEF 2) | protein interactions | 26230 | 15 | 9 | 19454 | 5460 |
RIGI,ANXA7,RHOB,DISC1,H2AX,UFD1,TOP3B,DNM2,TNIK |
| 9.577e-03 | -4.65 | CACNA1H (calcium voltage-gated channel subunit alpha1 H) | protein interactions | 8912 | 15 | 9 | 19454 | 5460 |
GNG2,TOP3B,KLHL1,USP5,VIRMA,CCR4,HNRNPL,RPA2,KCNMA1 |
| 9.577e-03 | -4.65 | EBI3 (Epstein-Barr virus induced 3) | protein interactions | 10148 | 15 | 9 | 19454 | 5460 |
IL12A,ARMC8,GOSR1,HECTD3,MAEA,SMAD3,S100A6,MDFI,ZMYND19 |
| 9.577e-03 | -4.65 | NRSN2 (neurensin 2) | protein interactions | 80023 | 15 | 9 | 19454 | 5460 |
MZT2B,SGTA,LMBR1L,RUSF1,TSPAN10,ZDHHC17,FITM2,MANSC1,CD1B |
| 9.577e-03 | -4.65 | CCDC127 (coiled-coil domain containing 127) | protein interactions | 133957 | 15 | 9 | 19454 | 5460 |
CETN3,CHCHD4,GHITM,VPS33A,ESR2,VPS16,CETN2,PDE2A,RNF11 |
| 9.577e-03 | -4.65 | TC2N (tandem C2 domains, nuclear) | protein interactions | 123036 | 15 | 9 | 19454 | 5460 |
GPBP1L1,DIRAS3,BRD3,KRAS,RAB3B,FBXO7,ERRFI1,CSK,RAB11A |
| 9.577e-03 | -4.65 | SPATA6 (spermatogenesis associated 6) | protein interactions | 54558 | 15 | 9 | 19454 | 5460 |
IP6K1,HNRNPL,MAGOHB,AP1M1,WDR83,WDCP,CSK,DDX39A,SNX17 |
| 9.577e-03 | -4.65 | RUFY4 (RUN and FYVE domain containing 4) | protein interactions | 285180 | 15 | 9 | 19454 | 5460 |
TRAPPC14,TRAPPC2L,TRAPPC6B,TRAPPC4,NDC80,CDKN2D,TRAPPC1,TRAPPC3,TRAPPC10 |
| 9.577e-03 | -4.65 | UCP3 (uncoupling protein 3) | protein interactions | 7352 | 15 | 9 | 19454 | 5460 |
STRBP,ZC3H7A,YWHAG,RTCB,YWHAZ,RC3H2,DDX1,HNRNPD,YWHAB |
| 9.577e-03 | -4.65 | CDHR5 (cadherin related family member 5) | protein interactions | 53841 | 15 | 9 | 19454 | 5460 |
KRAS,FITM2,VIRMA,LEMD3,JMJD8,RETSAT,ODR4,MBLAC2,EFNB1 |
| 9.577e-03 | -4.65 | GTF2H2C_2 (GTF2H2 family member C, copy 2) | protein interactions | 730394 | 15 | 9 | 19454 | 5460 |
GTF2H5,BRD3,XPO1,GALC,CDK7,SUV39H1,GTF2H4,ERCC3,PTS |
| 9.587e-03 | -4.65 | carcinoma | COSMIC cancer mutations | carcinoma | 16802 | 4833 | 16828 | 4835 |
USP46,SMAD2,PITPNB,LPAR6,POLR2C,GNAQ,DBNDD1,NGRN,RAD1,GIPC3,NFE2L2,CCDC167,RUVBL2,GOSR1,IGF2BP1,NCOA5,MMAA,PPIC,ARMC6,CHCHD1,NDN,SIKE1,SNX3,DBH,TBC1D5,CLRN1,CDC5L,LGI1,SLC35A5,TMEM19,OR2F1,CH25H,HPS6,TCP1,KCNH8,CRMP1,CNOT7,ADRM1,RABIF,CD80,PKIB,EMX1,HNRNPL,UBTD2,IREB2,NMRK1,TAF11,P2RY10,NKX6-2,GPR22,HS3ST5,PLAC9,SLC38A2,PFDN1,LIN7C,SSR3,SGMS2,ANXA7,NCSTN,TAF2,PRR19,UBE2N,ANO3,NGDN,CTRB2,CCL1,PSKH1,FKBP4,STX16,PI3,EIF5A2,SMURF1,DPPA2,PMP2,VDR,CTTNBP2NL,PTGDS,IL5,PEBP1,ADRA1A,TNNI1,FGF22,CX3CL1,PSMB2,CBX7,COL3A1,PAK1IP1,VAMP1,GLYATL3,ADRB2,SLC6A1,GPN2,TLR4,MYO1B,QSER1,SLC2A1,GPT,SRSF12,TPRA1,SASH3,TIFA,B2M,SLC52A3,CASP4,SLC15A2,SPOP,DEFB129,TRIM22,CYB5R4,FITM2,MRPL36,AMACR,NR0B1,DCK,ADH1A,EAF2,ITM2A,MCM6,RPS24,NUDT4,DCUN1D1,CYP7A1,DIRAS1,ABCE1,GINS4,PRRT1,SDS,PPP1CC,PAQR8,PEX26,BAZ1B,OR4E2,OR7D4,KCNB1,TNFRSF9,NOP16,ZNF32,DMAP1,LRRC8C,LYZL4,CST3,SCAMP5,PLEKHO2,ICA1,BCL2L1,YWHAG,ACVR1,VDAC2,DCTN6,MYH1,IFT57,EGLN2,KLHL28,EDEM3,TPPP2,RNF152,UQCRC2,MRPL33,LRRTM1,CXCL9,RBPJ,MRPL17,DUSP9,CFDP1,SIGMAR1,IFNK,ATP2B4,GATAD1,RGS10,PTGES3,ACTN4,RPS15,ASB1,QRSL1,VIPR1,FBXL3,PSMB11,HSP90B1,TCOF1,LRAT,EDDM3B,ISOC1,ZDHHC8,RETN,MCPH1,NKRF,MFSD6,POU3F4,MADCAM1,ASRGL1,MPST,PSMC4,JRKL,RFC5,IDH3A,PATE4,TMEM97,MED13L,NSDHL,NXT1,SLC35C1,RLN3,ANKRD50,CHMP1A,NEO1,PCCB,HSD17B3,ESAM,GAPDH,CLIP3,SLC25A42,VAC14,CRYGA,CBLN3,GRIA1,RNF208,YES1,PI15,HECTD3,FABP12,FGL2,HDAC5,RPL17,UBL4A,SERPINB11,GKAP1,GUK1,AGAP2,STX1A,FBXO3,IRF2BP1,UBE2B,CSE1L,ACHE,OR4N2,MNAT1,STAC3,FAM3A,FMO3,TNFSF10,CDK5RAP3,NEK9,CLDN6,CAPZA1,PDIA2,RNF146,SAP30L,FAM76B,SNAP23,BOLA1,GGCX,PAQR4,ELOF1,CCAR1,NTRK3,PICK1,TSSK1B,IFT52,ACOX1,F7,FADS2,PIK3R1,TSPAN7,EXOSC8,ZNF574,POLD2,KDM2A,KLHDC8A,SUMO1,DCLRE1C,OR10G3,OR2J3,G3BP2,SRSF1,SLC31A1,DIO3,COX6B1,ITGA2,UCK2,LMBRD1,FGF7,MAPRE2,CAV3,EPHA2,PRPF18,IGSF21,CDK2AP2,DDI1,COX17,RAB28,ELK1,FAM168B,CYP1B1,MDH1,MRAS,RALYL,MRPL41,MRPS35,ATP6V1G2,RAB6B,MMP14,INSIG2,DEFB124,LHB,CBL,KLHL23,HSDL1,ACOT6,IL12B,WDR6,NCALD,ANGPT1,COPS4,ZGLP1,KCNK17,PHF12,ZBTB33,GEMIN7,BAG2,DCP2,MED17,TMEM184C,NOB1,GRAP,EPYC,SELENOT,PHC1,BLOC1S3,TAAR6,PLXNC1,UGT2A3,CD38,MT1A,PNMA2,ANKRD49,CAMK2N2,CUTA,DLAT,RMI1,RIMS3,EIF4E2,IL13,GRM8,UTP15,MCM8,HP1BP3,OSGEPL1,PACRG,TAS2R16,TLCD2,EXOSC4,DNLZ,BUB3,SNX5,SLMAP,CFL2,ZMYM2,OR4N5,KLRD1,FASLG,CTBP1,EIF3E,CDC42EP4,MSRB3,DDT,JUP,ALKBH3,EXT1,TMEM74,IRAK1BP1,TIMM8B,CD52,CYP3A5,DCUN1D3,PHF1,LMNA,RNF41,ZNF7,DCAKD,PLP1,XPNPEP1,MGAT4B,LIMD2,COPS2,TRIM27,EIF2AK2,C1GALT1C1,LGI3,GTPBP2,TSHR,SLC25A20,NCR3LG1,NEUROD6,AIG1,INSM2,EIF2D,DYRK1A,DRP2,RAB31,OR8K1,STC1,KLHL32,SRGN,TAS2R46,G0S2,OR5I1,SATB1,TRA2A,PRMT5,BEND6,GANC,ACO1,CACUL1,PPTC7,PCK2,RALGAPA2,SFXN1,UBAC2,NME2,CD4,UBXN6,KCNF1,NR4A2,NOSIP,SLC25A45,REXO2,DTD1,GPHA2,NTF4,POC1B,LRTM2,CYB5R1,USP2,MYT1L,DCAF4,ARHGEF6,PCSK2,SLC39A13,CYP4F12,CPE,CDC40,SCN1B,TM2D2,NDUFB5,SUB1,OR52W1,NELL2,NOVA1,INPP5K,MCAT,SEC63,NUDCD3,IRF2,TM4SF1,BCCIP,ERP29,PTTG1,SNX2,NOL7,CAMK1,WFDC5,TACO1,NSA2,NXPH3,SSBP3,DEFB115,HRAS,WDR20,SYT4,RPP14,TAGLN2,RPL13A,FAHD1,TRIM8,IKBKB,HELLS,MITF,LCA5L,HTRA1,KIF3B,SPCS3,CLVS2,VAMP3,WDR83,VLDLR,CRB3,DHRS7,CYB5A,TFG,ELOVL3,MTX2,MAEL,CDK8,BSCL2,RNASEK,PHF23,IQCF5,COX10,LECT2,SLC16A4,POGK,HNRNPA1,ACOT8,TRIM52,NFE2,LRTOMT,NCKIPSD,DEFB121,CTSB,SKA3,ALKBH2,RPS29,SOX3,RPS4X,TMOD3,COX19,RSPH1,ZDHHC15,MAP3K12,FBP2,PPIA,CLCA1,TMEM88,CNOT6L,GTF2IRD1,CD1E,TRMT11,MRPL40,SMCHD1,B4GALT7,ZSCAN5A,VSTM2A,GABRG2,TFIP11,WASF3,PRKCQ,MEF2B,MRFAP1,IKZF2,CLEC9A,RPL8,NAT9,PGM1,HADH,ANAPC11,LACRT,SEPHS1,TOMM7,PCMTD1,RASGEF1C,MAP2K6,MAD2L1,CA10,GSTA4,RHBDD3,PPP5C,RBM42,FOXP3,LDLR,OR7E24,VPS4B,TMEM160,PYCARD,CUL2,SLC6A8,GHR,MED30,CXCL11,MED9,SOCS4,TREML1,INPP5E,ASB8,ORMDL1,CDC16,GNB1,GLTP,DISC1,CHID1,AVPI1,SSR1,SMARCD3,NETO2,RBFOX3,RING1,ZNF596,MCHR1,SFN,TRAPPC10,SF3A1,PSPC1,GNAI3,SYCE3,FAM50B,SFTPA1,STX10,TUBB,LSM14B,ZFP64,COIL,STBD1,FAM110B,TRIM63,PAQR9,IL4,THAP2,TIAM1,GPX2,DNAJC1,HCLS1,TRIM46,GLRB,EHHADH,EMP2,LILRB1,OVGP1,TLE1,ARL6IP6,HMG20A,BTF3L4,CYP27B1,PNOC,YBEY,NTPCR,IL15,MRPL10,GNG5,TMEM14B,NIF3L1,RRN3,DHPS,UTS2,NSFL1C,TMEM190,OGN,SCPEP1,PADI2,POLR2F,NDUFB10,POMT2,MOG,LRRC57,PLSCR4,OSGEP,SCN3B,NMI,RIMS4,NDUFA2,IFNGR1,TPGS2,NUP50,ZNF575,CCL20,MRPS7,ARHGAP5,VTI1B,FAM162B,GLT8D2,SPATA6,EIF4E3,MYOZ3,TCAP,RIC3,ARHGAP25,DES,PCDH9,ZRANB2,LIN7B,TNFSF13,FLRT3,STIM1,GRPEL2,LRIF1,TMC7,FTL,KLHL12,SERPINI1,IDO1,PPM1D,SLC25A28,SLC39A3,CXCL12,FLCN,MSL2,RSRC1,RPL35A,CD248,ZNF668,TUBA1A,RPL7,YTHDF1,CELF6,NAA50,FCGR2A,ERVV-2,MED31,SH3BP5L,NEUROG2,MTMR6,LUM,CCDC85B,SEMA6C,ICAM3,UNC50,HMX2,CHST11,PSMD12,CKLF,CCT7,PAFAH1B1,SLC25A11,KCTD15,PDCD1,HNRNPD,MS4A7,IFIT2,SECISBP2L,RAB33B,MCM3,CDC42EP3,RNF115,RASGRP3,ENTPD3,RCE1,MGAT1,RGS19,TOMM20,TRAF3IP2,PTGER4,BAHD1,DHRS7B,ZCCHC17,PSMB6,IZUMO1,PEG10,PIP5K1A,CHRDL1,NLRP6,RASL10A,METTL6,SULT1A3,TUFM,OR51M1,GNG13,IFNA2,IDH1,KRTAP12-4,VPS28,MPZ,SRC,CD2AP,MORC4,CISD1,LANCL1,PIK3R3,MKKS,SLC35B4,TERT,AP2S1,PGAM1,RNF121,UGDH,RPS13,CCSAP,EPO,ZNF280B,MMP21,EID1,CHCHD3,NFKBIB,HSP90AA1,CD1A,LPAR1,HDDC2,PPIH,FNDC9,DCUN1D5,FOLR2,PDRG1,SOCS3,PTPN22,LNX2,TYW3,SNX18,RFC2,CPNE1,GNB4,CNTN1,ZER1,ACTB,MATN4,DDAH2,CNR1,PLA2G12A,CAMLG,NPY,SLAIN2,DAD1,MFN1,ZBTB2,TAS1R2,GSTM2,NAA35,UBFD1,PPP4C,PPIG,NRBF2,EFHD2,PSMA2,DNAJB2,GRXCR1,GGT7,NICN1,TMEM208,RAB30,RSAD2,GABRA2,COMMD5,SST,PFDN4,GABRB2,ARMC1,TFEB,SYVN1,HSCB,CES5A,CCDC122,PPP1R12A,IL6,GRID1,RERE,FGF10,TLR2,HECTD1,DYNC1I1,LGR4,PSMC1,MED21,PAIP1,TTC32,SSRP1,OCIAD2,TWSG1,OR9K2,NDUFS3,HPGDS,RLN2,OSBP,GOLGA5,DNTT,MORN4,GIMAP4,XXYLT1,RPAIN,UNC119B,TBC1D4,AGAP1,SLC6A12,TRIM10,UBE2E3,UBE2M,PIR,OR5AP2,MOSPD1,ELAVL2,FCHSD2,ISCU,SMC4,TNNC2,GTF2E1,OR8I2,AK5,RAB22A,CLVS1,FAU,CYP2F1,PSME1,KBTBD4,PNO1,DRAM1,VKORC1L1,IL1RAP,SMARCA5,CNPY4,ELK4,FAIM,BAK1,ATP1B1,GPR85,PPP2R3A,SMAD4,DRD1,SLC22A8,SLC1A3,FZR1,RILPL2,TM9SF4,TCEANC2,LRRC1,NUP37,USP5,MXI1,FERD3L,GPBAR1,ITGAV,LDHB,RPF1,FOXP4,RNF126,TMEM182,AKR7A2,AURKAIP1,FXR2,SNRPD3,LAMTOR3,ZNF175,TP53INP2,GPSM3,GOLPH3L,TNNT2,STK11,TESK2,COMT,RPS27L,SEC61A2,ELAVL4,LY6G6C,RHCE,ANGPTL2,TMEM106A,BAALC,FKBP10,PHAX,RIMKLA,GPX4,EXOC1,FGF12,SEC62,SYS1,IL1B,GPR26,PLAA,RPRM,BAP1,DOHH,FUT1,MEF2C,DRAP1,LRRC4,LITAF,ARFGAP3,ARL4A,KLHL7,MCHR2,OR51A4,ZNF330,DET1,CSTB,RNF14,GTF3C3,PRRG1,SAT2,GPNMB,IRF6,RAF1,DNAJC10,RGMA,ALG2,MBLAC2,PHKA1,COG1,RPL10L,SCYL2,CYTH1,PDE9A,SLC1A1,CCDC71,CCHCR1,RPS5,SNAPC2,SLC22A12,FOXP2,CYP17A1,UBE2F,UBN1,TPSG1,RAP2C,LAMTOR1,ADNP,DDX5,EIF4A3,KATNAL1,TNFRSF14,TXNRD1,TMOD1,KCNMB2,GTPBP1,RPS11,GSTK1,NAE1,NDUFA12,NUDT5,DNAJC25,EGFL8,ILVBL,ARL15,AZI2,LRRN1,CD1B,GCC1,DNAJC27,KDSR,ZFAND2B,DNAJB6,AOX1,PSMA5,B4GALT1,STARD13,TGIF2LX,ATP1A1,CRKL,NLRP1,CNPPD1,TMEM199,GZMK,FBP1,RP2,CENPP,STX12,G2E3,GLRA1,RBM18,QPCTL,TOPBP1,MTG1,RPL3,PROM1,MRPS18A,C1QL3,TRIM11,VMO1,LCMT1,YIPF4,CSNK2B,TMUB2,RHOB,MAX,OR4K17,NRSN1,HOXB1,BOLA3,DEDD,CDC42EP2,PPM1G,FLRT2,TMEM209,GLYAT,GFI1,MYD88,MRPL52,FCF1,CD1D,PLN,E2F4,CBY3,PEX5L,COMMD2,TM9SF1,SVOP,MAGOHB,FAM118B,CBX5,ARL10,MYCT1,TRMT1L,KCNMB1,GABARAPL1,CD46,GNAI2,UCK1,CDC123,GTF2A2,ACTL9,RNF20,GPR15,COPS7A,PPARA,STOML2,OTUD6A,MICB,NUP153,TOR1AIP2,RERG,POLR3F,RPL35,FRS3,RRAS2,ATL1,TPT1,SNCB,TSC22D3,USP14,NANP,TXNL4A,CISH,GNA14,CXCR6,AGPAT1,EIF2S2,ZMYM4,BTG1,CHMP5,ASB3,RNF39,HDAC6,PBLD,TMEM176A,CNTNAP1,ANAPC13,EYA3,DUSP26,SESN3,CDSN,ZNF692,SLC25A44,TESC,THY1,YWHAB,PSMD14,EDNRA,ST6GALNAC3,TBC1D24,SPOPL,SYT2,TMEM95,LEPROTL1,NR1H2,BMP1,PRPF31,PHB2,MMADHC,TTC1,STXBP6,PDE1A,DAPK1,LILRA1,TPBG,KCNQ5,NFYB,SLC25A17,LRWD1,EEF1G,ARRDC3,ZCCHC12,NME4,FNTB,YIPF5,TOB2,SLC6A4,PDSS2,SFTPC,ZC3H15,ODC1,SLC25A23,DSN1,PLAC8,CYB5R3,NDC80,RPP21,SNAPC5,OR10G2,RAB13,MAP1LC3A,SELENOF,RNF26,PATE2,CDK5,GNG3,MRPL51,MOBP,PKIG,TSG101,MAMDC2,ADCY2,THBS3,TRUB1,SNAI2,CALR,DRG2,SHMT1,NDUFA4,CYTL1,SLC45A3,HEXB,SYNGR4,PPFIBP1,OAF,CD151,RPN1,KCTD9,TLR6,DLG1,P2RY11,IL3,MSX1,CHRM1,DPP4,PRDX2,HEXIM1,LMO3,UGP2,EIF2S1,MRPS33,LMBRD2,PAX6,STAT1,ZNF507,TMEM31,PTN,SSBP1,F10,KCNA3,SKA2,NDUFB7,NEK2,ZNF526,NDUFV2,PC,RAB5A,APOBEC3D,BVES,RAB14,GOLGA7,TMCC1,REP15,SDC4,WASL,CD79B,OR4N4,ZBED4,DYNLT3,SP4,SPEM1,CYP3A43,PDE4B,TTPAL,PMAIP1,CCIN,UBE2L3,EIF3G,MEPCE,CPLX2,PRND,ABHD10,HUWE1,SREK1IP1,FTSJ1,CNTROB,AKR1C1,MRPS11,CSNK1G3,RAB39B,NINJ1,ICOS,BLCAP,ITGB5,RGL2,TRIM34,NDUFC2,TMEM205,TCEAL8,LXN,YIPF3,RPS2,B4GALT4,CAV1,DDAH1,GPR35,HFE,NDUFA1,ALG11,FAM53C,MCL1,HCAR1,GSTA2,TMEM127,TRIM29,OIP5,CORO6,RB1,DPH5,PNMA3,ZBED1,CTXN3,PLSCR1,PTP4A3,DCAF12L2,COMMD9,STK3,CBLN1,HSPB2,LILRA2,TNKS2,LY6H,NT5DC1,MRPS18C,TRIM36,PROK1,JAK2,PAQR3,CREBZF,FRZB,FAM149B1,SPP1,TSR2,CHRM3,ARL2BP,ING2,ZNHIT6,PLCB1,GPR17,GPC1,PRSS23,CITED1,TXNDC17,ARL4D,LIAS,TNNI3K,CPLX3,NPY1R,GCLC,PSMD10,EPHA4,CTU1,KCNJ2,GXYLT2,PSMB7,TNFAIP6,FBXW7,DMTF1,PLG,DLK2,CDK12,GRM1,PCGF6,OR4K2,SHPRH,KCNJ10,SPATA2,ADORA1,SLCO3A1,TAF1D,HOMER3,CXCR3,MAGEB10,SLC25A1,HNRNPF,STAMBP,ZNF511,CEND1,EHD4,FAM81A,TM4SF18,TNR,OR6X1,BOK,LSM14A,CAPN2,OR8H3,SLC8A1,ICAM2,ABHD8,OST4,STARD3NL,YWHAZ,AASDHPPT,MARVELD1,RNF222,REEP4,TM4SF20,CCNA2,GJA1,MAGED2,SURF2,SLC29A1,GABRA1,PRNP,CAND1,HSD17B10,TMEM89,MIS12,CBX3,DR1,GTPBP8,HS2ST1,TRPC1,LYPD6,ELMO2,BCL9,ASPA,SSX2IP,SYNPR,BCL6,E4F1,TMED9,GSTCD,GTF2F1,DLST,CA2,SNX10,USP6NL,MTDH,PET117,SGTA,TPPP3,ZNF263,CPT1B,RBM27,ZBTB39,CNN3,ANKMY2,LY96,AP1S2,TMEM47,MAD2L1BP,AKR1B1,ADORA3,APEX2,SF3B1,TAB1,TMEM185A,NDUFS2,PAIP2,PIK3CA,IVNS1ABP,SNRNP40,FAM83B,JAKMIP2,CDH11,ERVV-1,PSMC3,CRTC2,GSTM4,TSPAN15,TMEM38B,NPM3,NUDT2,GH1,BAX,PEBP4,ATP1A3,PSD2,COCH,FEM1C,PIK3AP1,COX6C,PICALM,LST1,XAF1,VTA1,RPIA,COX6B2,TMEM170A,RNF133,PRKRA,TSPAN17,ZNF451,PRKCE,WDSUB1,GNRH1,DBR1,TAS2R13,TRAPPC13,UBE2E2,FSTL1,HGS,RHOBTB3,POLR2L,POLDIP3,SLX1A,CRISP1,DPH3,LRRC40,ELK3,CD81,MT1E,TFB1M,SUMO2,SNRPB2,LZTFL1,KLF3,CCR4,CHRAC1,GGH,TNF,PPAT,IL17F,NUDT9,CYGB,KLHL1,FOXA3,SESTD1,CARTPT,ABHD12,BANF1,PARP2,NF2,RPL26L1,PHF13,CGGBP1,MRPS34,IGSF11,CYP2C9,DUSP21,TRIM45,ATAD1,MGAT4A,RBBP8,SGMS1,OLR1,SLC19A3,NDST3,FBXO8,PRL,MPPED2,CDC7,SEC13,IL2,TNFAIP8L1,VMAC,NBN,TBC1D25,AIPL1,PEX13,NHEJ1,WDR11,FHOD3,SLC35B3,TYROBP,XRCC5,ACCS,TIMP4,ADTRP,SNRPG,ZDHHC4,WDR5B,CDC20,TRIM26,IER3,NUCKS1,CENPL,KLRC2,TOX4,CYTH4,CPNE2,IFT172,TMBIM1,RAMP3,FXN,SUPT3H,UPRT,SGIP1,MRPS17,MECR,UBE2G2,MRPL9,FEM1B,MACROD1,ZNF518B,ADCK1,CYBRD1,FAM151B,FAM136A,SLC35E4,PRR13,SLC25A5,OAZ1,WSB1,LYZ,TOPORS,SLU7,VEZT,PTP4A2,FAM3C,MFAP3L,IRF7,TMEM165,OR8B4,KLHL25,RPE,SULT1B1,HAUS2,OR5M9,GALC,RP9,ELFN2,LRRC8A,CNPY1,SSPN,GNGT2,LBX1,NKAP,RDH11,PIH1D1,KCTD3,SYNGR3,BRAP,TANK,MPG,MBD3,CDC23,DMPK,ELFN1,IGF1,CCR7,SNAP25,RXRG,GORASP2,THUMPD1,TTC9C,PELO,GMPS,ANXA4,IL18BP,RASL12,GALNT2,RRAGB,SNRPE,GRIK1,DLGAP4,CMA1,SCML1,ZFAND6,TAPT1,TYMS,MED10,NAA16,GJC1,RPS20,RUNX1,SLC12A2,ATP8A1,CIAO1,KIF3C,GHRL,VPS18,ZNF581,SUCLG2,PDE7A,DUSP3,RASSF8,CLEC6A,KCTD17,SSBP4,RBP2,AQP11,TLCD1,FKBP1B,LMO2,EDA2R,LCORL,OR13A1,PSEN1,MAGEC2,YTHDF2,FAM161A,PDE12,ANKRD6,SRFBP1,PFKFB2,EIF5B,ARHGAP12,MREG,ACER3,DIRAS2,TRAM1,TADA3,TMEM196,AP1M1,ECHDC1,FUNDC1,UBA52,IMPA2,TRAPPC6A,MDC1,MTCH2,ITM2B,CCSER2,SP1,MGMT,GIN1,TKTL1,RPL18,TBCCD1,TRAF6,VPS72,KRIT1,ROCK2,FUBP3,KCND3,SPRY1,RPS10,CLDND1,CCDC106,ETNK2,PPP1R11,MDFI,MSH6,RAP2A,ZDHHC16,TEX261,OR4D5,FAM133B,RNF10,GP9,OR51E2,POLE3,KRTAP8-1,APLNR,CYP4V2,NCAPG2,SRI,CNPY3,DTWD2,PSMD3,POLR1D,GPR160,STAR,TRIP4,RPL10,PDCL,SUPT5H,SLC25A24,SPINK9,GLCE,GK5,SSNA1,PTGFR,IL2RB,IP6K1,P2RY4,FBXW4,ST3GAL2,TAS2R7,CD209,LDB2,YPEL4,PRSS8,RNASE9,GADD45G,RPA2,TMEM107,TRAF3IP3,PIWIL1,CCDC90B,RGP1,TAB2,SRPK2,UNC79,THAP1,FBXL4,CD34,CPXM1,PRCP,EID2B,DCTPP1,TMEM100,OR4A47,SIN3A,CDK7,PLAC1,SCAND1,PSMD7,CTTNBP2,RGN,FKBPL,RAB6A,PYCR2,ZNF428,PDE2A,TNFSF8,CDIPT,ARFGEF1,MED22,NOG,TLR8,PMPCA,TNFSF15,SLC6A2,CD40,AIP,CRY1,THOC3,PIGA,GLOD4,BOLL,MX1,RBMS2,TGFB2,VPS54,SLC25A27,ZNF622,ATG9A,S100A11,OR1M1,RUSC2,CD9,GRPR,GADD45A,IGFBP3,TMEM183A,DPEP3,BTG3,PNPLA4,PIAS1,TMEM115,NPC2,NUPR1,PARD6A,LRRC28,TCEA2,HSPD1,EIF1AX,RNASEH2C,SLC22A6,SPG21,TIA1,DDR1,EXOC3,SAP18,TMEM81,CAP2,PPWD1,PQBP1,GPRASP2,TICAM2,FAM20B,FHL3,HSPA5,GNA11,SERTAD2,HSPB6,MPV17L2,CRYBA1,THAP8,WDR45,NRM,TMEM229B,HINFP,NUFIP2,CMC1,GNB3,CCDC3,VAV2,BTG2,ITGB8,NR1I3,PAIP2B,LRP10,TRIM44,ACSS2,DEFB1,IFRD1,MAP1LC3B,PDLIM3,PRSS37,ATF3,CTLA4,RBM5,RANBP1,BHLHA9,TMEM176B,CEBPE,RPL22,DLG3,B3GALT4,RHOU,PDE6A,IMP4,TRNP1,HELT,TIMMDC1,SERPINB9,UBE2V1,MT1X,SNX11,RPLP1,POPDC3,RETSAT,SLC7A11,MET,FZD6,ADIPOR1,GAL3ST4,PRM1,GFM1,SSH3,HOXB8,EMX2,SEC61G,CENPM,CCDC22,KDM1A,NDFIP1,PSMG2,DTL,TNFAIP8,ABHD2,CEP70,ARL6IP5,ANKRD46,CTDSPL2,SNN,SNRPA1,CYP26A1,GMNN,ISG20,TMEM87A,NUDT1,RALB,FKBP2,PRSS35,UNC45A,TBCEL,HAPLN2,SAP30BP,EDC3,AANAT,ANKH,YKT6,VPS26B,CAMKV,ARL5B,F2,ESYT1,BIRC5,MFSD3,LDB1,TRAPPC3,NRGN,CSRNP3,GMDS,WNT2,ZMAT3,BRS3,TRAF1,RSL24D1,CLK1,SKAP2,KCTD20,SERPINA3,RASSF4,PSMB4,HERC3,SEMA3C,DOK6,LSM4,IRF9,HSD17B8,DDX39B,CGRRF1,NETO1,CDR2,PTGER2,C9orf72,NAA30,ZSWIM7,RPL31,WTAP,SSBP2,GDAP1L1,PDCD10,LRRN4CL,UQCRC1,NOC4L,CRHR1,AKR1E2,PRPS1,OLA1,HAS3,TSPAN3,BAD,MGST3,TAF9,MEA1,HMGN4,SCHIP1,COX7B2,CMBL,CDKN1B,OR6C4,RFX5,TMEM198,TRAPPC2L,MAT2A,NMRAL1,SCG5,PHOSPHO2,SIAH1,STRADB,LRP3,NCK1,ST8SIA4,USE1,TMEM220,TMEM168,CD200,ZNF655,TEX19,TRIM62,HNRNPAB,GPR78,PLEKHF1,AHSA1,ZBTB6,KCTD16,SLC15A1,WDR12,IAH1,MLN,KLF12,FBXO31,VSTM2L,MAP1B,ZDHHC17,CNOT8,PIGK,PELI1,NEU1,AMELX,VSTM4,PDCD1LG2,RAB1A,GLO1,TEF,ANKRD10,SCN2B,ADD2,SOD2,TCTA,PCP2,TMEM231,GTF3C4,MMP20,C1QL2,PLCXD3,REG1A,DNM2,OR4K13,TSPYL4,CLRN2,SRD5A3,DCAF16,ALG5,SDHAF1,DEXI,SUGP1,STARD5,FMO1,ABCC2,ACTR1B,STAP1,HTR2A,SMARCB1,ECD,CD59,ETFA,APMAP,PRELID1,AQP3,RIMKLB,PSMG4,HIGD1C,TLR5,LCN1,RFC4,HS3ST3A1,TICAM1,GPM6A,OR2D3,PNPO,COTL1,SOX9,KCNG3,CHST10,GAB1,ITPRIPL2,JMJD8,AKT2,APEX1,PRSS1,PSMC5,OR9I1,TRMT5,BCKDK,ZCRB1,MED4,APOC2,CYB5B,NAP1L5,SEMA7A,MRGPRX1,LIPT2,HPCAL1,THG1L,PDLIM4,GABBR1,ERCC3,TIMM13,XBP1,RPF2,TBC1D1,GPR34,NACC2,CHRM5,DRD3,MTA3,EMILIN3,NAP1L3,CEACAM5,DIS3L,CA14,CEP57L1,OSBPL8,TACR1,ARHGAP19,ACTL6A,ACP2,NDUFAF6,FOSL2,GNPAT,SETD3,GPR75,TMEM126A,CHTOP,SYPL1,ZNF343,DIO2,EGR1,ZNF436,WBP11,STARD7,MAGEA4,STT3A,RRP7A,CCDC126,RBM3,CORO1C,RACGAP1,ARHGAP15,RHOH,ERLIN2,HYAL2,UBE2S,NPBWR1,RPSA,PIK3CG,SMG5,NUP62,RNF139,PLP2,ABCF1,DUS4L,DYNLL1,LYPLAL1,HSDL2,OPRL1,RAB11B,STX5,ARL6,CCND3,IRF4,CSRP1,LEMD3,CMTM7,SPATA4,TBC1D16,SLC7A1,CA12,ADRB3,FMOD,SLA2,IFNAR1,SDR16C5,MARCKSL1,CCL11,RAB9A,RXFP2,RPAP3,HINT1,TNPO2,THOC6,PYCR1,OAZ3,WBP1L,VCPIP1,SLC39A10,MCCD1,TCEA1,HM13,BCAS4,PGAP3,MB21D2,LCN15,UFSP1,PTPN5,RNF182,RELL1,SMAD9,TIMM17A,LIPA,CCL24,SNRPD1,JUNB,ALCAM,PREP,CDC26,SHC3,PIGC,ARFGAP1,MVD,STK38L,CYP4F22,RPL28,CACNB2,HCFC1R1,FIS1,PDF,EDEM2,SRP72,SLITRK1,DDIT3,LSM5,DCTN3,IRF2BPL,PRKCB,PABPC5,HCFC2,RWDD1,SLC25A3,COPE,RBM41,DYNLRB2,CKS1B,SPAG11B,HBP1,SEC14L5,RPL4,RGL1,SUV39H1,TTLL10,SIGLEC5,HDAC11,ATG16L1,DIRAS3,TP53TG5,ZNF200,IZUMO2,TPST1,AGGF1,LCP1,HNRNPH3,GJB1,GCHFR,PCYT1B,CSF2,PRELP,KRT8,CHCHD2,SKP1,CLP1,CLPX,OR5AN1,INA,CFTR,ATG3,VPS39,MYLIP,SUPT4H1,FAM174A,SART3,PTPRZ1,IFI16,PSMB10,CHMP1B,CDK17,ART5,TMEM39A,CDKN2D,ESD,GPR37,ATP6V1D,VWF,PCBP4,MLH3,APOBEC3B,FAM193B,BLVRA,PITPNA,RAB32,CRYBA4,CRYZ,FOXC2,PSMD1,BARX2,MPP1,MED27,SRM,RANBP10,ADH1B,SPDYE4,OR4M1,BMPR1B,HS3ST1,TULP3,GAD2,METTL18,RSBN1L,SEC61A1,TTR,RGS1,SDHC,ASB11,FAM83A,NOL12,RHOG,COX7B,CDC42SE1,BGLAP,CXCL10,LYRM2,FOXD3,FBLN5,MAEA,EID2,ZNF345,KIAA1958,ZNF770,TPD52L1,DUSP18,RPS28,UBXN2B,SMUG1,SVIP,CDH7,ASCC1,SLC37A4,HNMT,FA2H,ERRFI1,SERTAD1,KCNIP2,ZHX1,LPCAT3,GPR83,ZCCHC7,PHTF2,PPIL3,CTSA,DPAGT1,NPB,ZBTB26,LRRC14,EMILIN1,PDCD5,PRDX3,BTBD10,ARF1,EIF2B2,ZMYM6,GNG11,PHF7,MRPS26,HMGB1,THAP6,CKB,TUBA1B,CXXC1,RPL7A,LSM12,FIG4,DOK5,DCTN4,SEC22A,MAP2K3,ZDHHC24,PPT1,B3GALT2,ARF6,MRPL12,FGR,RCHY1,SPHK2,FAM20C,UBE3A,OR4B1,PDE6D,OR5K1,PDZK1IP1,TNIK,S100B,LRFN3,RIT2,CACNG3,IFNA13,ZC3H14,CBFB,ASPM,EFNA5,ZC4H2,CETN2,TADA1,SMARCE1,PITHD1,SH3BP4,LEP,SNRNP70,SERINC1,PLEKHF2,GLIPR2,SPCS1,TDP1,MID1IP1,IL21,RPL19,MSN,FGF16,POU5F1,HBM,ZNF362,SLITRK5,DDIT4L,RNASE4,SAP30,DICER1,SLC6A7,MAGEB1,EZH1,ARGLU1,RNF7,TECR,MRPL16,KRTAP4-1,MAP3K3,ARL11,FHIT,UBE2I,UCP2,TMEM106B,MED29,MXD1,MFAP1,LAMTOR2,SLC41A1,PNRC1,TSSC4,MAK16,ALDH1L1,POLL,NONO,SPRED1,H19,EMC4,SIVA1,GFOD1,SNTA1,SNAPC1,GPR37L1,NDUFAF2,TCP11L1,SOST,HPCA,SV2B,ZNF805,OR2A2,EIF4EBP2,MMACHC,TRAF7,MTMR12,DUOXA2,RAP2B,ABHD16B,ZBTB42,TNFAIP3,TAPBPL,ETV6,RRAGA,SIRT7,FYTTD1,NOL4,IQSEC1,SNRPD2,FAM13B,ADCY3,DCAF5,ESR2,CDK6,CWF19L1,RAB8B,CTNNB1,CYP2D6,SOCS2,INTS12,SFTPD,OAZ2,CLEC12B,VPS4A,ENPEP,NAB1,SYNGR1,RTP4,ZMAT5,LSM6,PRKX,FGF13,PROX1,ZNF174,USP38,SLPI,USP39,CERK,OR2W1,RPGRIP1L,CCND1,WFDC13,ACOT13,TMED3,FBXO9,COX7A1,LCN6,OTUD6B,SETD4,BMPR1A,FAF2,SPINK13,RHCG,ARHGAP21,SCG2,AP3S2,S100PBP,TMEM33,MRPL47,MPHOSPH10,KLF10,NFYA,S100A10,FAM200A,STX8,DUSP1,TGFB1I1,BATF,TOLLIP,PWP2,RAB3C,MTAP,CTSK,CACYBP,URM1,CETN3,DCAF8L2,NDNF,AP1G2,ANP32B,CHST9,CPT2,PPIB,BPGM,CDKN3,CD164,NUP107,OR52M1,SCAMP2,SPEF1,SLC5A6,CYP4F8,PRKD3,NLGN2,DEK,CTSD,COA4,PGAP2,MRGPRX4,FABP5,AKR1A1,SPATS2L,NOP58,NFE2L1,RBCK1,MRPS25,KIF2A,BACH1,MIA2,INPPL1,ING5,DEGS1,CRYBA2,CCDC42,FCAR,NPTN,POU1F1,CYC1,PTDSS1,ID1,SLC35A2,ARMC8,ENTPD4,XPO5,INTS10,SURF4,TF,CREB3,RNF103,KIAA0040,THRAP3,EEF2,GJA10,EFHC1,SLC25A32,XPO1,EXOC2,ZMYND11,TXNRD3,SLC7A4,ZNF513,GPR162,APOBEC3C,RNF187,GSK3A,PRCC,LDHA,PFDN6,NUBP2,UBXN10,PCDHA5,SLC20A2,DNAL4,FATE1,ATP2C1,RC3H2,NUDT19,RANGRF,ABCC5,THOC1,GLE1,CREBL2,TXNIP,AQP4,CCL25,GNMT,IL23A,PSMD6,FURIN,DHX9,SLC39A9,ZSCAN1,OR51S1,EIF4EBP3,WDR37,OSR2,CXXC5,ENDOD1,CIRBP,ANKIB1,EIF2B5,SH3GLB2,GALE,FUT8,WBP2,GTF2A1,UTS2R,NEK7,LASP1,PHKG1,SPOCK1,MOB3C,SERPINH1,RPL37A,HSPE1,CLDN14,ZKSCAN1,STAMBPL1,SIPA1L1,PGBD2,NUDT16,OR6M1,GXYLT1,B4GALT6,HSPB1,KCNA2,LHFPL1,HADHA,LEAP2,DHX16,SOX21,RAB4A,TRA2B,WNT7A,LEPR,STX17,EIF1AD,NAA11,ISYNA1,APH1A,NDUFB8,CXCL1,PDIA3,FRA10AC1,XPOT,PELI3,CDC37L1,SNAI3,KRR1,NLE1,RPRML,MSX2,KCND2,CCL21,NDUFA5,TRMT6,PTCRA,NEDD8,CXCR1,FGF17,HBB,RAP1A,ACAA2,UCKL1,WWP2,RABAC1,FBXO30,TIGD7,CD2,POLR2I,ST13,LPXN,RASGRP2,DFFA,IL34,NQO1,IPP,TBCE,SPATA2L,IGFBP4,AKR1C2,NPVF,LMBR1L,OPA3,TAC1,CHRNA7,GAS8,KIF1C,CDKL2,CD3G,BRMS1,PAOX,RBM23,TMED1,OCEL1,ADAT1,HEXA,BRI3,OXNAD1,TBC1D10C,MAGOH,NKX3-2,CCL19,MLF1,GTF2E2,LBH,JAK1,FGF1,INO80C,AZGP1,ABCB1,HBE1,PSME2,AZIN1,CDCA3,RAB3B,SMAP2,KTI12,DNAL1,NDST1,TNFAIP8L2,DEFB116,DHRS3,LYG2,MFSD6L,MX2,TMEM213,GPBP1L1,ZCCHC10,SYN3,AAMP,FZD4,MEST,WDR77,MTPN,ATP6V1G1,TSEN54,SERPINB10,TMEM215,FBXO42,ZNF24,MMP9,BTF3,S100A6,DYNC1I2,CYP27A1,ZYX,UBAP1,CDC73,LHX2,TMIGD1,DNAJC5,SNAP91,MYH2,SLC7A9,HEBP1,PACSIN3,ALKBH4,PGK1,ROPN1B,VRK1,KBTBD2,GSTO2,ATF4,CTNNBIP1,GNG7,GRSF1,RARRES2,KPNA1,CSNK2A1,PIWIL4,RS1,KIT,LSM3,OR4D9,AFTPH,JOSD1,P4HA2,SUPT7L,AGK,ANAPC2,FBXO32,SMCP,CCT5,ENPP4,MCOLN1,PSMB5,SORD,SBK2,SLC39A7,IMPACT,CD58,AGER,FKBP14,IDH2,RAB18,ZNF593,ARMCX5,PRPF4,CCDC47,TTC4,SCFD1,GHITM,PGA4,CACNB4,TUBG1,RPL15,TACR3,CIB3,PRMT2,CAMK2G,TMX4,SRP54,BUD31,CCDC127,PEX3,RCVRN,FAM89B,KCNJ11,PPP3CA,CRYGB,CD200R1,HCRT,CAMK2N1,FGFR1,SHC1,PYGM,OR4K1,HEY2,PCDHB8,RBM17,ZDHHC14,PKNOX1,ADRB1,FRMD8,RFX4,SPTAN1,SLC35E3,RNASET2,NPY2R,LRP12,FAM199X,PAEP,RABL2B,NIPA2,CLDN11,TRAPPC1,RMND5B,RBBP7,SLC25A21,PGS1,NFIL3,ZBTB38,HECW1,TRIM37,PTPN1,HNRNPC,SETD5,SPR,GALNT12,ARFIP1,PPARG,ACTA2,TRIM21,SIX5,ARMCX2,CCNI,ASMT,RAB11A,PPIL4,CDO1,CRABP2,RPS23,DPP10,PRRC2A,SF3B4,IL20RB,DKK3,COMTD1,FNDC8,APEH,FGD2,DLX1,AKT1,L1CAM,SNX20,FIBIN,WDR38,TLR9,MRPL13,EHBP1,MDM2,MGP,SPRN,GSTO1,TMEM156,GALNT1,AK2,SOCS5,PSMA3,CCDC69,RND3,CNP,NUDT3,B9D1,LYAR,GNRHR2,TOM1L2,EXOC8,PFDN5,UST,SDR42E1,UBR7,PDIA6,CD99L2,PRIM2,SNRNP27,TRIM32,KLHDC8B,RNF141,DOK4,ARHGAP1,PLA2G5,KLK9,MRPL23,GDI2,GFM2,E2F6,ZMPSTE24,EXOSC1,EFCAB7,GPR89A,POLR3H,TRIM3,C1QC,TMUB1,ATP6V0B,TMEM219,EDF1,ZNF207,UGCG,MEAF6,LYPLA1,RPS14,LIG3,SLC17A5,ZNF671,SLC25A31,KIAA0232,ATPAF2,CLU,LMO4,GLUL,CNIH4,CDK5R1,NRP1,NCKAP1,ID4,SEC14L1,ZNF319,APOBEC3A,ZNF397,XAGE5,SLAMF9,ZMYND19,TAAR1,CCR6,OR8B8,IRF1,P2RY1,ING1,STRBP,NAIF1,TRIM23,NHP2,CHRM4,CCT2,UBE2D3,ATP6V0E1,ARMCX1,UBE2A,FGFR1OP2,GABARAP,PRPSAP1,GRPEL1,ELMO1,TCP11L2,LTBR,OR4D11,GAL3ST1,CASK,MRPL24,MRPL50,ZNF304,SNAPIN,SLC30A5,KLK3,ENY2,RAG1,IMMP2L,MEF2A,HSBP1,DHRS4,SLC35A1,RMND1,MIOS,PPP1R2,FAM78A,OSM,IL15RA,SLC38A9,TLR3,GPAA1,ADGB,JAKMIP1,SENP5,IDH3B,GALNT4,CYP11B1,PYDC2,CTNNBL1,GRM2,CHDH,GNRH2,CYP39A1,HSD11B1,MYL12A,SWAP70,LRRC69,FAM8A1,ITK,EIF4H,NCR3,IPO8,TMSB10,CIDEB,ARMC7,ATAT1,TMEM123,DSTYK,CCR2,AIF1L,ZC3H7A,ZBTB5,RER1,FCN2,RGS7BP,CDKN2AIP,SFRP4,SYP,ATG4A,ZNF862,CSRNP1,MRPS23,FUNDC2,HSP90AB1,POLE4,GPHN,ISG20L2,TOM1,BCL7B,GPR65,SEC61B,TEX30,CHGA,GBE1,PAPSS2,TCF23,HTR5A,TMX3,DNAJC22,EIF2B3,TOP1,TMEM144,SRRM5,NRSN2,GPR137,SNX17,BCS1L,APOO,MYO6,NDUFS8,CYP2C18,ZNF740,F9,PGPEP1,NKX3-1,GCNT3,OPRK1,ACAT1,TMEM114,ZNF287,TMEM184B,KDM4B,CLDN4,LAMB2,SLC13A5,RAB3D,RUVBL1,SDF2L1,CXCL3,GTF2B,NKIRAS1,OAS1,GIT2,OR4Q3,HTR1F,LDOC1,GPAM,PDCD4,CREBBP,PRPF19,RDH10,TGIF2,GREM2,POPDC2,GPX6,ACBD7,FAM98A,CDC42SE2,RPLP2,TRIM54,IK,CRTAP,LCP2,UHMK1,ERH,ALKBH5,ADIPOQ,ANKRA2,CTDSP1,CCNB1,FAM162A,CRYBB2,AKAP14,NDUFAF4,TFCP2,CLDN1,ABHD6,METTL2A,CSGALNACT1,R3HCC1,SAT1,COL1A2,RMI2,SMU1,SLC35D1,MBL2,GTF2H2,MAP3K11,PTS,TOR2A,JPH4,AMIGO1,EDEM1,GNG2,METTL14,VAMP5,LRP6,TAS2R40,MRPS21,PYROXD2,STK24,LCA5,NDUFB4,RAC2,CEP97,ZNF501,IFRD2,ST3GAL5,POR,SLC32A1,FAM163B,PARP11,CSNK1A1L,SOX2,ST3GAL1,DERL1,IL18,PRKAB1,UQCRH,DPEP1,IRF3,MTHFD2L,CD36,ERV3-1,KLC2,PAX9,STXBP1,STOX2,PCMTD2,TSN,STOML3,STAU1,RNASEH1,DNAJC3,TMED7,KLK6,FKTN,SLC41A3,SERINC3,RGS2,STMN2,NME1,DUSP19,PDHA1,ADPRH,MBD5,NOS1AP,BCL10,KCNMA1,BRCA1,PCDHB1,ABHD4,RBM7,TRAF2,KCNK13,CDK4,NPR2,NR1I2,CNNM4,DPY30,GPX3,PROS1,TMEM204,B9D2,EWSR1,ELP3,YAF2,MRFAP1L1,DTYMK,TRIM24,TGFB3,ACSL4,CIB2,MTRF1,ZNF592,EED,MRPS16,ABHD14B,FAM219B,CCDC25,TES,LMNB1,BECN1,GMPPB,ADO,CALHM2,VMP1,SLC19A2,CBR4,MSMP,HSPA8,EMP3,OSTM1,CHMP2A,ITGA6,CSNK1A1,PELP1,COMMD8,TFE3,IFNA10,DEFB114,MT1M,RNF113A,EFNB1,SH3GLB1,THTPA,PREPL,TSPO2,OLFML3,GOLGA7B,RPLP0,UBE2V2,IL10,FUT9,PHYH,NTN4,RTKN,HOXD12,ADIG,ZBTB17,BCAP29,FABP7,CD274,B3GALNT1,CREB3L4,EIF3K,SPECC1L,NAT2,KHDC1,RINT1,BZW2,OR10G9,TSPAN5,TMSB4X,EIF4E,TRIM5,CALHM3,LHFPL4,COX4I2,CDKN2C,SNAPC3,BLOC1S2,SNCG,IGBP1,AKAP12,SSU72,DDX39A,RAB40AL,STAT6,OR10G7,ACADSB,SNX24,ISG15,WIF1,FN3KRP,DYRK1B,PHYHIP,RAB9B,AMT,INPP4A,KCNIP3,ARCN1,EZH2,FGFBP2,B4GALT3,PDYN,ZFP1,CRBN,CD226,VPS33A,SACM1L,CTNNA1,RAB2A,WDR44,GPIHBP1,TRAPPC6B,CCNF,VAMP2,BEND5,CMPK1,SNRPA,AP1AR,SMN1,PCDH19,PNP,RAB5C,WEE2,SELENOK,STK38,TIMM10,CAV2,IFI35,FBXO25,PSRC1,CSTF2T,C1QL1,RAB37,SLC6A11,FOLR1,IL6ST,TMEM59,RPL23A,LYNX1,ELMOD1,PLEKHJ1,MLF2,TIMP1,DERL2,TXNL1,SLC25A4,MRTO4,PTHLH,SMAD3,PPP2R1A,EIF4B,LDHAL6B,CCDC65,SELENOV,HMBS,CD2BP2,TDRD7,RBMX2,NDE1,AMY2B,ZBTB45,ABHD13,HRH3,RAB1B,INHA,OR5L1,RGS5,RPAP2,ACTL6B,FAM168A,LY6G5C,UBE2D1,SNIP1,SLC4A8,PGM2L1,ROGDI,SLC23A2,GYS1,AKIP1,SOS2,PIWIL2,PPFIA3,OTUD7B,SDHAF2,MED11,CLIC2,STX18,ORAI3,ELSPBP1,SLITRK2,RBFOX2,FOXN2,CDKN1A,GK2,OR14J1,CPSF2,CDH8,PCGF3,GPX5,TRIQK,TCEAL7,GDE1,TMEM14A,NGB,UQCR11,GLT8D1,MOV10,TAF5L,MYEF2,PNPLA8,TOP3B,TEX12,B3GNT2,HIGD2A,CASP12,TMEM91,ZCCHC9,SLC43A2,KLK5,LIX1,CAB39,DDX4,MRGPRX2,GRIA2,LRRC24,FLYWCH2,CYB561D2,GMPPA,MT2A,PPP1R16A,PXMP2,ATP1A2,DDX42,SLC7A14,BNIP3L,CLDN8,CXCL14,ADAMTS1,TUSC3,RPL6,SPRR1B,RPP25,RAN,RBM12,GLIPR1,SQSTM1,FMO2,TMEM177,BICD2,CREB1,SERPINA5,KIAA0408,RNF122,NAPG,KCNH1,CCL17,KIAA1191,DLG4,GTF2F2,PAFAH1B2,OR2H2,HSPA14,CXCR4,CDH13,NPY5R,POLR3B,LCN9,BRD9,PGR,HAND2,NUS1,SRP14,TMEM106C,PLEKHA8,KRT7,MANSC1,GJB2,WDR3,ZNF609,TMCC2,SELENOS,KCNK10,SLCO1A2,ACP6,SYNJ2BP,TMEM164,APLN,OR4F6,CRYBB3,TMEM203,TAS2R5,FOXS1,PTRH2,ACTR2,KLHL15,RFXANK,TRAM1L1,PLAGL1,PAPOLB,SESN2,PPP1CB,TRAM2,MPV17,FCHO2,CHST1,EHD1,ISCA2,UPF3B,RABL3,ZNF576,GCA,RAB33A,CRYGD,FAM107A,RNF167,PPDPF,TNFSF18,DNAJC8,GIMAP2,GNPNAT1,TOMM40L,FERMT2,EIF3J,UTP23,CHI3L1,RNASEL,TNRC6C,SPTBN1,TMEM50B,JUN,IFNG,CD47,S100A8,HIRA,RHOJ,CBLN4,WWP1,CMAS,RAB23,SFT2D2,PTGER1,OPHN1,SUMO3,OGG1,ZNF687,CCR3,YPEL5,ABRACL,PPID,RFTN2,TPPP,RB1CC1,SLC35E1,CAPZA2,NAA60,CCL8,STX6,OR2A25,FANCG,PLA2G15,MAPK1IP1L,TAPBP,HNRNPA2B1,RCBTB1,GGCT,ATP6V1C1,LHFPL2,ACAP2,SCD5,MAFG,NFKB1,PRKAG1,HNRNPK,PAFAH1B3,OAT,MRPS28,RIOK2,POMP,OS9,RPL26,EGLN3,CLDN22,DYRK2,FOS,RPL27A,NUDT12,CBLN2,TYW5,SNAP29,JAGN1,NDUFAB1,HTRA2,USP8,TMEM147,COX8A,LGALS8,COX20,DHX38,GPR171,PTK7,PGRMC1,METTL15,NEUROD2,BABAM1,CINP,FBXW11,CNDP2,PPFIA2,THBD,OR4D6,BCL7C,IL1A,AGPAT5,PLD3,PCYOX1L,CREG2,FBXO44,DKC1,ARPC3,HR,LRRC3,DNTTIP1,CD247,FZD3,RHOBTB1,IKZF5,HNRNPA0,CHST2,NXT2,CTSC,NDUFS6,TMEM126B,UBE2K,PDE1B,PIK3R2,DDX23,PCNA,SPRED2,OPRM1,CDAN1,PABPC1,GNG12,NTRK2,TWIST2,APOBEC3G,CNRIP1,LPAR2,FKRP,USP15,OR10A4,ELMOD2,RTN4,GLRX5,GNAZ,SIAE,ISX,GAMT,TOMM6,ARG2,DNAJB9,RNF144B,MUL1,SMG9,GNG10,TMA7,CTXN1,MAPRE1,NRN1,MME,METAP2,ZFAND2A,SEC22C,GFPT1,SDHB,ATG4C,SNRNP48,FRRS1,CENPW,RWDD3,TXNDC12,RORB,CKS2,ABHD5,CXCL13,EPHX1,MOXD1,RPA3,CCDC160,SIT1,FDFT1,NEGR1,ADAM21,CLDN24,CLDN3,UAP1,THAP7,PTAR1,MGAT5B,CRLF3,UCN,DEPDC1B,INO80E,PTEN,RLIM,IER2,CHPF2,NDUFAF3,CFC1,SHISAL2B,SCGB1D1,ILDR1,NLRP3,CCS,RASD1,OLFM3,SCG3,BMPR2,COMMD3,PPP1R1B,RND2,RBM22,RRM1,RPS16,KRAS,KDELR1,TOM1L1,BAG3,ZNF365,ORC5,ILF2,OXSR1,ZMYM3,CRIP1,PSMB1,DKK1,HERC4,NR2F6,CNTN2,ASNSD1,CHIC2,CHCHD4,FBXL19,LAPTM4A,MRGPRX3,SUFU,MTA2,CCDC86,OXTR,KCNC1,SLC38A7,PGGT1B,MRPL18,FGFBP1,MFSD5,PSORS1C2,POP5,G3BP1,CHAC2,METTL21A,DBT,RAPGEF5,ELOVL7,TPD52,DSTN,DAPK3,RPS27A,PCDHB13,SLC16A1,NUF2,TMEM101,HINT2,OR13C8,GPX1,TRIM15,RELL2,GRAP2,RAB27A,RPS7,NPPC,PSMD4,DHX15,OVOL1,RHEB,FBXL14,RPS6KA4,GANAB,TSPAN18,XCL1,BBS5,ZNF664,MAT2B,MLC1,OCRL,PDHB,DDX46,CCDC134,SLC30A7,TCF19,SLC6A6,PMP22,TMEM254,SERPINA1,OR2Y1,STX11,LARP4B,UBB,SH2D1A,SLC11A2,PPP2R5E,NPSR1,LMAN1,HSPA13,ANKRD34B,LSM10,LRRTM3,DAAM1,SCLT1,MRPL11,PRR3,IL22,EPCAM,PCDH17,SAV1,TAGLN3,STAT2,SRSF7,UBA3,CBLL1,TOR3A,GLRX,TMEM179B,BFAR,TOMM22,REEP3,ST6GAL1,CSGALNACT2,HENMT1,RPL7L1,CSTF3,GNPDA1,B3GALT1,COMMD6,KCNJ3,AFAP1L2,TMEM30A,UBL3,IMP3,IRAK4,TMEM170B,TMEM117,NDUFB6,MRPL34,GNAO1,CYP21A2,NCDN,FASTKD5,CST11,SFXN2,SNX22,STAT5A,COPS5,EIF4A2,OTX2,MAGEH1,FEZ1,PRDM4,FPGT,LRRC3B,PLCB2,MAP2K1,APOBEC3F,HSD17B6,TMEM167B,PEA15,RNF8,AKAP8L,CEP41,EP300,ADAMTS10,MRPL20,AR,IFI6,OR8B12,PPM1K,GSTP1,LLPH,CCL2,CGB8,TMEM45A,RNASE1,NLRP9,FAM43A,LAMP2,TMEM237,PTPN4,CHRNB2,GPX7,OR10P1,RIT1,SOSTDC1,MORC2,ELOVL1,SSR2,TPM3,SNRPB,EFNA3,SEMA4C,SLC2A3,RABGGTB,FBXO7,SPIN3,ANP32A,CLLU1,RPL23,CTTN,STOM,HP,VAMP7,TNFRSF1B,CDNF,TGFBR2,CEBPG,USP3,CAPN1,METTL22,CYP2C8,ASZ1,TMEM70,MPDU1,VAMP8,TTL,PMM2,PRMT6,PRSS12,PPP3R2,TIMP3,CLEC18A,SMAD1,SPC24,AQP2,ZNRF1,CHST13,FKBP8,KLHL24,GABPA,PPP2CB,RCL1,SF3B5,PPAN,IL2RA,RAB19,UMPS,CD1C,SS18,MRPL22,CDCA7L,POLR1B,CER1,CHCHD6,SIAH2,UPK1A,HOXC4,EPS8,RFXAP,MTM1,BIRC2,FCGR2B,NUDT7,IFIH1,NR2E1,DROSHA,ORC6,FLOT1,THOC2,STARD4,FAM177A1,DCTD,SCNM1,MCM4,CEP19,CHMP4C,PDAP1,SOX14,FAM219A,SLCO2B1,CX3CR1,IGF1R,UBP1,MAVS,KLHL22,LANCL2,APOBEC3H,GLRX2,PRKACB,ASB7,VDAC1,CLPB,FEN1,KLF1,ODAM,CLEC2B,SEPHS2,CBR3,JKAMP,ADD1,FCGR1A,DNAJC19,VGLL4,SCML2,CLDN12,PKP4,GPR176,ELF5,CHKB,CCNY,CNOT2,OTOS,CRHBP,ZNF326,PLEKHO1,MYBL2,GSTM5,ERAS,KLF4,COPS7B,DENND2D,OR10A6,OR4D2,RNF34,ACBD6,TAF10,FAM53B,PRDX1,NFKBIA,NPW,TUSC1,PREB,ATG7,TRIM68,LRRC8B,ETF1,GTDC1,UBIAD1,LRRC61,TSNAX,POLR2B,UBE2W,PARL,DHRS13,RFC3,SLC7A8,FBXO22,GPM6B,REG1B,ACP5,HLF,SERPINC1,TMEM59L,EGFL7,ATP6V1A,CCR1,REN,SOD1,TBC1D13,ATXN10,NCBP2,ASTN1,SMPD2,DTWD1,AVL9,DECR2,TP53INP1,IQCK,FAF1,VEGFA,TM4SF19,CRAT,NOTCH2,NAPA,PTPN11,SOBP,TMOD2,GNPDA2,HARBI1,TMED5,TCEAL1,PFDN2,LTB,USP16,CLCN6,AK3,HMGCS1,SLC25A12,DDRGK1,RPL32,PSMA1,DRGX,HDHD3,SHOC2,PTH2,MTF1,RNF148,PRICKLE2,MSTN,PPP1R1A,RPL27,CLDN9,SYNCRIP,SLC35F2,TRMT112,VGLL2,DIO1,SLC16A10,IFNB1,UBL5,BTN2A2,CSH1,POLB,MNS1,UBASH3B,POLA2,SEMG2,CCNH,KIAA0513,SPSB3,TOR1B,KANSL3,FAM83C,UGT1A1,MRPS9,LTA,ABCG2,NKIRAS2,FAM181B,ACVR1C,RBM38,IL1R2,TMEM41A,KLF9,PIP4K2C,STUB1,SERPINB1,GSTA1,UBLCP1,SRSF2,TRAK2,AVPR1B,ST7,TEX264,SNRK,ZNF821,SLC25A10,CTXN2,HINT3,VRTN,RPRD1A,GTF2H5,DDX50,BST2,PPP2R2C,SPON1,STK4,SLC22A17,TNKS,ST8SIA5,CYP1A1,PLS3,GNL1,ZNF473,SELL,KIAA1143,ATP1B3,DNAJC2,GNB1L,PPY,CRYAB,ROMO1,RNF11,CYTH2,SYNGR2,APOC4,TAF7,OR4S2,WDR82,TLR10,ZBTB25,CD28,NAB2,FXYD6,CRADD,PPP1R3C,KCNAB1,AGTRAP,SEMA5A,APBB3,MCMBP,S1PR4,FAM169A,TNFAIP1,TMEM11,LAMP3,CHPF,REEP6,MATR3,CNOT6,RPS26,RNF40,DDX1,KDELR2,DAP,DPM2,RNASE6,TP53I3,KLHL3,CFL1,BRIX1,IRGQ,CD86,PNMA5,MANBAL,SLC2A8,PSENEN,ENO2,OXCT1,ZNF704,KBTBD6,EXD2,PTPMT1,UBE2H,FARSA,SLCO1B3,GOSR2,FGF23,CYP2R1,SLC25A39,CD14,PRR5L,RANBP6,G6PC3,CCL27,ZC3H11A,HTR1A,TMX2,METAP1,SFRP1,ELF1,WSCD1,SHISA2,KCTD10,MAB21L1,RAB35,ASF1A,PPP1R8,CCL28,MKLN1,VPS26A,CMTM6,EEF1E1,TMEM50A,SMG8,MYC,TAS2R39,LILRB4,CD40LG,SEC11A,FEM1A,CALML5,VAPB,PNMA1,SP2,HEBP2,SLC6A3,CASC3,CNKSR3,TCF21,RPS9,GEMIN8,MYL6,TIRAP,SEC23A,TUSC2,OR5V1,PSMG3,GPR173,TOP2B,AGR2,CACNB3,TTC23,PCBD1,NLGN1,MORF4L1,TMEM174,CPSF4,LCN8,AGA,CD63,AKAP1,CLEC1A,DNAJC24,PARM1,PSMA6,PCSK9,KBTBD3,PIWIL3,IL2RG,FTH1,SNX1,SLC35F1,PSEN2,CCM2,ALB,ACO2,VPS16,CLN8,SYK,SLC25A26,TNFAIP8L3,SLC48A1,CDC42,GSTT2B,DUSP10,BACE1,SLC38A1,SURF6,BRD3,FAR2,TMEM108,DVL2,TESK1,TTC33,OR2AT4,C2CD4C,RPL39,KLHL26,BET1L,MAP3K21,WRAP53,MMD,GAS2,UCHL3,TRAPPC4,EEF1A1,PAAF1,TFPI,PRKCA,NPTX1,CLIC4,MAGED4B,COX11,HNRNPH2,HMOX2,ADM2,IZUMO4,AHCYL1,ALDH1A3,GINM1,SAMM50,KCNJ8,ENC1,PYGB,TRIM6,HOMER1,PDE8A,PSMB9,SLC4A10,FOXP1,EXTL2,RCCD1,ALPL,SLC20A1,ADIPOR2,LAP3,C2CD2,EFHD1,RPL9,TST,RNF5,DGCR8,LRRTM2,API5,PHACTR1,SAMHD1,CRYM,TPH2,SPRYD4,KCNS1,FKBP1A,SRXN1,DNAJC30,P2RY12,EHD3,MRPS18B,ST3GAL4,ZMAT2,DOLK,NT5C2,ERVFRD-1,AKT3,MAN1A2,POLD4,CCDC92,RBP5,EIF3D,DNAJC4,ELOVL4,PAK6,CHMP2B,CSNK1E,SKA1,PIGY,GRB10,FAS,ATF1,ABCB9,TMPO,UBTD1,MAD2L2,COX6A2,POLR3GL,RBBP4,OR5A2,CPLX1,PLSCR3,ARMCX3,CUL3,COX16,SDC2,ACVR1B,FAH,CAMSAP2,CTDSP2,RPL10A,DNAJB4,TXNRD2,C2CD2L,AKAP17A,RAD21,RAP1B,SNX14,AIFM1,POLR2G,COQ10B,ACTR1A,LAT2,FITM1,CARHSP1,NPC1L1,KLHL9,TIMM8A,MAP1S,BHLHE40,BPIFB4,PI16,MRPL53,NLRP2,HDAC3,RPL29,GLRA2,ANAPC4,GDPD3,ARPP19,LRRC4B,TOMM40,GREM1,FABP4,COX4I1,MPHOSPH6,NDP,TMEM42,SNX33,MED23,USP13,SDCBP,FGF3,DRG1,CEP85,ERLEC1,SRPRB,POLR2D,SNX12,CNTFR,KRT222,PDP2,SMNDC1,NEURL2,GPR146,OPTN,KCTD11,CLEC7A,APPBP2,ARPC2,MYL12B,GINS3,ENHO,ATP6V1E2,ZHX3,IL7,SRSF4,NECAP2,ATXN1L,EXOSC3,SH3BGRL,PID1,HAX1,LRRC20,EGR2,OR1F1,RPS3,CHN2,TMEM60,HBEGF,CALU,AIF1,SRSF10,FOXJ3,ORMDL3,RAD23B,USP30,UFM1,NMBR,LGALS3,MAP4,HHIP,LUC7L3,RAB3A,DDIT4,SMYD3,KPNA2,LCN12,FAM91A1,CTNND1,YIF1A,KBTBD13,OR10Q1,CA8,HMGA1,OR1S1,SH2D5,FOXI3,UTP6,TSPAN11,MND1,GGPS1,IPCEF1,AUH,TTC8,TFRC,ZNF267,IDE,ZNF177,ZNF652,HSD17B11,PPME1,C1QTNF1,DNAJC7,CD83,RPL12,KCTD12,UQCRQ,SOD3,DUSP22,GFOD2,ADAMTS20,YWHAH,MRPL49,GABRB3,FAM187B,MTMR2,ICAM1,PLCL1,PABPC1L,LSM2,TMBIM6,CCT8,TFDP2,ZNF22,C1D,ACTR3B,MIF,RBM15B,ZNF189,EEF1B2,AP2A1,APTX,HRH2,SPINT2,RGMB,ZNF688,BCL2A1,TMEM45B,FBXO11,RBBP9,SPSB1,HMX1,WNT10B,DGCR6L,LRRC8D,ETFB,VIP,NTNG2,SLC25A46,TMED4,HEXIM2,TBC1D17,HSD17B1,PTRHD1,TOX,IRF8,KPNA6,RWDD4,CYB561,BET1,FCER1G,GSTM3,SYNDIG1,TSEN34,FTSJ3,SENP8,STX7,MGST2,GADD45B,HBA1,OSGIN2,LIMS2,GPC4,MZT2B,NECAP1,PKIA,TRIM35,TRAFD1,PPM1B,TP53,PPM1M,NFKBIL1,CRELD1,INMT,PRDX6,TAX1BP1,KRTAP3-1,AP2M1,KIN,GABPB1,SCGB1C1,ARF4,TAX1BP3,ZNF790,RDH12,CALY,TNFSF12,GABARAPL2,PML,DNASE1L1,PSMA4,OR10A7,SERTAD3,ZNF250,MT3,EIF1B,DUSP6,MTHFS,PPIF,SETD7,ZBED3,DAG1,RPS12,CYB5D2,TXN,MAF1,DCAF4L2,RPRD1B,SNRPN,TSPO,LYPLA2,POP7,STYK1,RNF181,OMG,GPD2,CELA3B,FBXL7,LBR,CYP11B2,PHF21A,COX5A,THNSL1,SLC1A2,RHBDL3,TRMT61A,CAMP,OLFM2,ENO1,GNPTG,SERPIND1,CHST7,ORAI2,CRYL1,RPL24,ELOVL6,ALOX5AP,TFPT,NUP35,MECP2,ZNHIT1,PRDX4,SLC25A14,RASL11A,CLSTN3,TBC1D19,RGS6,CSTA,SYBU,EXOC5,SERPINB6,NAA15,EBLN2,WDR55,RALA,FTHL17,F11R,ADK,G6PD,PPP2R5A,VASH1,TLR7,GAPT,PTGES,ACADS,RNF128,TLR1,OGDHL,CAPG,CCR5,SAR1B,RHAG,IL12A,OR5B3,BRMS1L,HCST,FBXO34,PAPOLA,DHRS1,CHORDC1,ZBTB16,ANAPC16 |
| 9.594e-03 | -4.65 | ZNF668 (zinc finger protein 668) | protein interactions | 79759 | 223 | 79 | 19454 | 5460 |
RPS9,PRKRA,RBMX2,RPS3,RPL19,SRPK2,RPL10,ESR2,RSL24D1,RPF1,RPL13A,MATR3,PRPF31,CUL3,RPL7A,NOP16,RPF2,ZNF250,NSA2,H1-1,RPS5,MRPS25,FTSJ3,RNF113A,AATF,NOP53,RPL4,STAU1,RPS15,NPM3,DGCR8,NOTCH2,ZNF770,RPL26L1,RPLP0,ZNF574,APOBEC3C,RPLP1,RPLP2,PRR3,SRSF1,KRR1,RPL12,RPL8,SRP14,SURF6,NOP9,MDM2,PRNP,RPL7,LYAR,RPS16,SPPL3,RPS10,RPL6,SPATS2L,DDX50,RPL10A,NOL12,RSBN1L,RPS2,MPHOSPH10,RPS24,RPL3,RPL23A,NKRF,RPL31,RPL17,RPS13,IMP4,PAK1IP1,H1-6,ZMYM4,MAK16,H1-3,H2AX,TP53,RPL18,RBM34 |
| 9.594e-03 | -4.65 | ALK (ALK receptor tyrosine kinase) | protein interactions | 238 | 223 | 79 | 19454 | 5460 |
HSPD1,SRPRB,PFDN1,ARF4,DUSP19,TFG,ERRFI1,ACTN4,NUDCD3,NUP37,TUBB4B,STIM1,NUDT19,HGS,CRKL,SRPRA,RAB35,PTPN1,UBE2N,SDC4,CORO1C,FAAP100,SEC23A,CDCA3,EIF2S1,CDK9,PRKCQ,PIK3R1,PFDN5,SHC3,DDRGK1,CDK5RAP3,ESYT1,SHC1,NCK1,OSBPL8,DNAJC3,P4HA2,HADHA,NUBP2,IRF7,PTN,PIK3R2,GPC1,HSPA5,UNC45A,H1-5,GPC4,NTPCR,VAPB,EIF4B,ARCN1,LEMD3,GAB1,GXYLT1,SEC61A1,PLCB2,PDLIM3,MB21D2,COPE,PTPRZ1,ACTB,SRC,SEC63,JAK2,VEZT,PTPN11,SOCS5,SDF2L1,MYO6,ARFGAP3,BICD2,PFDN4,NRP1,EPHA2,SCFD1,HSP90AA1,PFDN6,SERPINH1 |
| 9.594e-03 | -4.65 | Golgi stack | cellular component | GO:0005795 | 149 | 57 | 19108 | 5553 |
LYPLA2,APH1A,CLIP3,GOLGA5,TRAPPC4,FUT1,PSENEN,TOM1L1,CSGALNACT2,MGAT4B,INPP5E,B4GALT1,ZDHHC14,CHPF2,CHPF,GALNT2,LYSET,ST3GAL4,RAB30,ST3GAL1,TMEM87A,SLC30A7,ATL1,MARCHF4,ST6GAL1,GAL3ST4,ATP2C1,MOB4,SLC30A5,NSFL1C,B4GALT6,TMEM59,CSGALNACT1,ST3GAL2,B4GALT3,VRK1,TMEM115,SCFD1,NSG1,OCRL,STX16,GCC1,MGAT4A,GOLGA7,MARCHF9,GOSR1,GOLPH3L,FUT8,GPR89A,VCPIP1,SGMS1,GALNT1,TMED3,SAR1B,B4GALT7,RAB14,GGTA1 |
| 9.603e-03 | -4.65 | SLC27A4 (solute carrier family 27 member 4) | protein interactions | 10999 | 105 | 41 | 19454 | 5460 |
RAF1,B3GNT2,CCDC47,OTULINL,GP9,RPA2,RPN1,OTULIN,OGFOD3,TSPAN15,TMT1A,RPA3,NUBP2,HSPA8,LPAR2,PCNA,STAU1,IMMP2L,EPS8,PTPN5,ADIPOR2,FAM20C,MYC,BECN1,SYP,PHB1,CD63,DUSP6,PTPN1,CCNF,LMBR1L,SEC61B,HSD17B11,EIF2B5,ARMC6,SMUG1,GNAI2,ESR2,VIRMA,EGLN3,CIB3 |
| 9.603e-03 | -4.65 | CIAO2B (cytosolic iron-sulfur assembly component 2B) | protein interactions | 51647 | 105 | 41 | 19454 | 5460 |
DCP2,HSCB,KRAS,MSL2,PRIM2,DUSP9,ABCE1,ACAA2,CDK1,RSAD2,MOB3C,PAFAH1B1,RAF1,COMTD1,TOP3B,ERRFI1,CNP,ELP3,MAK16,PPAT,VIRMA,CETN2,NUP35,ILVBL,IREB2,EGLN3,CCNF,CTU1,GGT7,EIF5A2,ELP6,YAE1,RIT1,DNAJB6,UBE2H,CUL3,CIAO3,CIAO1,EDC3,MLF2,PPP1CC |
| 9.603e-03 | -4.65 | GLB1 (galactosidase beta 1) | protein interactions | 2720 | 105 | 41 | 19454 | 5460 |
TRAPPC4,YPEL5,TRAPPC2L,TRAPPC14,CTNNBIP1,DNAJB2,IDE,TRAPPC6B,ATP6AP2,G6PD,FZR1,LGALS3,CSNK2B,TRAPPC10,TRAPPC3,LMBR1L,NUPR1,PAK2,TFCP2,FOXS1,PLS3,RPA2,MAD2L1BP,CHMP4C,CTSA,H2AX,NEU1,ZC3H14,PSEN1,MEPCE,RIGI,SLC7A1,HSCB,ABCE1,DNAJB4,NUP50,RPA3,TRAPPC1,TMEM106B,FOS,DLG1 |
| 9.612e-03 | -4.64 | IL-2 Signaling Pathway | WikiPathways | WP49 | 42 | 23 | 5310 | 1910 |
PIK3R1,STAT5A,MYC,SHC1,CRKL,STAT1,NMI,IL2RB,AKT1,FOS,SOCS3,MAP2K1,IL2RG,SYK,PTPN11,JAK1,IL2,CISH,HRAS,JUN,IL2RA,CBL,RAF1 |
| 9.612e-03 | -4.64 | Eukaryotic Transcription Initiation | WikiPathways | WP405 | 42 | 23 | 5310 | 1910 |
GTF2H4,GTF2H2,POLR1B,TAF7,POLR2I,POLR2G,POLR2C,GTF2E1,MNAT1,GTF2F2,POLR1D,GTF2A2,POLR2F,ILK,GTF2E2,POLR3B,ERCC3,GTF2B,CCNH,POLR3H,TAF9,CDK7,POLR2B |
| 9.623e-03 | -4.64 | TONSL (tonsoku like, DNA repair protein) | protein interactions | 4796 | 102 | 40 | 19454 | 5460 |
RPN1,H2BC1,MACROH2A2,SLC25A3,H2AJ,H1-5,RFXANK,H2AX,CFTR,TULP3,NPTN,KRAS,H3C1,ASF1A,FBXW7,MCM6,SSRP1,SLC25A5,XRCC5,EWSR1,AGR2,H2AC4,BRCA1,BRD3,OST4,MYC,UBXN6,GPR17,HSPB8,AR,MCM3,MCM4,SNRNP40,EGLN3,DYRK1A,CCNF,AIFM1,NFKBIB,EEF1AKMT3,MACROH2A1 |
| 9.623e-03 | -4.64 | ING1 (inhibitor of growth family member 1) | protein interactions | 3621 | 102 | 40 | 19454 | 5460 |
PCLAF,EZH2,KLF3,LMNA,DMAP1,SAP30L,SMARCB1,SCLT1,TP53,ACTL6A,KLF12,SAP30,SOX2,DDX39A,KPNA2,TGIF2LX,RBBP7,SGF29,PAX6,SAP18,EP300,PCNA,YWHAZ,NQO1,YWHAB,SFN,HNF1B,CREBBP,BRMS1,AR,YWHAH,YWHAG,BRMS1L,RBBP4,SPPL3,KLF9,SMURF1,SIN3A,GATAD1,COPS2 |
| 9.623e-03 | -4.64 | CSTF1 (cleavage stimulation factor subunit 1) | protein interactions | 1477 | 96 | 38 | 19454 | 5460 |
DCUN1D1,PRNP,BMP1,TOP1,CSTF3,ESR2,OPTN,CPSF1,FBXO32,CCT2,BRCA1,ATG3,CYP1A1,SNRNP70,USP15,MIR140,LMO2,MYC,HNRNPA1,RACGAP1,SNRPB,MPG,G3BP1,ZBED1,TOLLIP,FAF1,SNRPA,MIR206,MIRLET7I,FEM1A,NUPR1,ATG16L1,PAFAH1B1,SNRPN,DDX39A,CNPY3,CSTF2T,GTF2E2 |
| 9.623e-03 | -4.64 | DNMT3B (DNA methyltransferase 3 beta) | protein interactions | 1789 | 96 | 38 | 19454 | 5460 |
CDC73,LRP6,H1-1,POLB,PLEKHJ1,SUV39H1,SMARCA5,CUL2,CUL3,CBX5,APEX1,RPS10,RBBP4,EED,ZBTB18,MACROH2A1,UBE2I,CREB1,SIN3A,MTA2,POLR2C,CBX3,EZH2,H2AX,MAP1LC3B,MAFG,SUMO1,UBE2W,PIAS1,RIGI,NEDD8,RBBP7,H3C1,SMC4,BACH1,CMTM6,DHX9,HELLS |
| 9.623e-03 | -4.64 | GNG12 (G protein subunit gamma 12) | protein interactions | 55970 | 96 | 38 | 19454 | 5460 |
CDKL2,CBL,EPHA2,RHOB,USP14,BTF3,HDAC6,MYC,GNB1,VIRMA,ESR2,HNRNPL,COPE,CYB5A,GNB3,CCNF,CD274,GNAQ,NUPR1,MET,PDCL,LACC1,SLC12A2,MED23,TFCP2,CDKN1A,CAPN1,RAP1A,TOP3B,FLOT1,GNB4,MEF2A,ADRB2,HSCB,PMAIP1,HSPA8,BCKDK,DDX39B |
| 9.623e-03 | -4.64 | OTUB2 (OTU deubiquitinase, ubiquitin aldehyde binding 2) | protein interactions | 78990 | 96 | 38 | 19454 | 5460 |
RNF126,NCOA5,TRAPPC13,CCR1,EEF1A1,POLDIP3,TRIM63,RBCK1,HNRNPF,GTF2I,NEDD8,TRIM26,MAVS,FAM168A,ARRDC3,RTCB,TRIM21,NMRAL1,TRIM5,RPL3,SP1,TRAPPC4,TRAF6,NPSR1,GAPDH,CTNNB1,CDIP1,TRIM8,MYC,PRPF19,TRAPPC6B,SUMO3,SIAH1,CPLX3,TRIM54,TRIM27,EIF4A3,UBE2N |
| 9.623e-03 | -4.64 | DSN1 (DSN1 component of MIS12 kinetochore complex) | protein interactions | 79980 | 96 | 38 | 19454 | 5460 |
ETFB,TMEM101,SPC24,GNPDA2,SKA2,ADNP,CHAMP1,CBX3,HGS,PML,PCNA,MIS12,PCGF6,MDC1,RNF20,NDC80,PIK3R3,MLF1,DSN1,MOV10,PPP1CC,EXOC5,RNF40,DNAJC7,HSP90AA1,HOMER3,S100A6,CCNF,YBEY,POLR3B,RBBP4,FZR1,PYGM,NUF2,NAA11,EGLN3,CBX5,LRIF1 |
| 9.630e-03 | -4.64 | IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha) | protein interactions | 3419 | 99 | 39 | 19454 | 5460 |
RPA3,SOD1,BAP1,CCT8,HINT2,IDH1,EP300,HSCB,HUWE1,STAU1,ETFA,ADRB2,RIGI,IMMP2L,CCND1,IDH3B,ACTN4,PPP2R1A,CFTR,RPN1,IDH2,RAB4A,RPLP0,SLC25A3,MTRES1,CCNF,UQCRC2,UBE2N,PSMC5,GATD3,PSMD4,PRNP,SUCLG2,ESR2,ACO2,MYC,MTG2,PYCR1,CUL3 |
| 9.630e-03 | -4.64 | TPP1 (tripeptidyl peptidase 1) | protein interactions | 1200 | 99 | 39 | 19454 | 5460 |
TFRC,IDH2,NDUFS3,GSTP1,CYC1,NLRP2,CCDC47,SPR,UQCRC1,HADH,POP5,NME4,HSCB,TOMM20,MPST,BAP1,ABCE1,HSD17B8,SQSTM1,TERT,POR,STN1,BRCA1,MYC,EMC4,LAMTOR2,ATP5F1B,PRNP,EGLN3,ELK1,NDUFS8,APEX1,ESR2,UQCRC2,CCNF,CORO1C,GATD3,CYB5A,ATP6V1A |
| 9.630e-03 | -4.64 | MSH3 (mutS homolog 3) | protein interactions | 4437 | 99 | 39 | 19454 | 5460 |
STAU1,H3C1,PIWIL2,MSH6,COIL,LTO1,RPA3,SLC39A9,COX8A,SYVN1,PCNA,RPA2,KLF3,NUPR1,FURIN,RAD1,TOP3B,CDC42,TRIM29,SUMO2,VIRMA,MAD2L2,RCHY1,ZNF330,CCNF,BRCA1,TLR9,BRD3,EMX2,DPP4,ATG9A,LMO2,KARS1,MYC,CSK,H2BC9,OTUD7B,HDAC6,MTPN |
| 9.651e-03 | -4.64 | TNECROSISFCT | prints domains | PR01234 | 6 | 5 | 5227 | 1528 |
LTA,LTB,TNFSF15,FASLG,TNF |
| 9.653e-03 | -4.64 | CPSF2 (cleavage and polyadenylation specific factor 2) | protein interactions | 53981 | 154 | 57 | 19454 | 5460 |
CUL3,PAPOLA,MYC,SMARCA5,RIT1,CDC73,RAN,CCNF,CPSF1,MED17,RBBP4,DUSP3,ESR2,CSTF3,PSMB6,PSMB3,ATG16L1,CPSF4,CSNK1A1,HECTD1,SNRPA,SMARCD3,RPA3,PSMA3,P4HA2,KDM1A,UFL1,HSCB,MBD3,WWP2,HNRNPA1,SNRNP70,CLP1,ASB7,PSMB5,PSMB4,SSU72,SIN3A,TOP1,SUMO2,FZR1,CDC5L,POLE3,SUPT5H,RAF1,SAP30,CSTF2T,EZH2,SMARCB1,MTA2,SNIP1,MRPS11,FAM76B,KRAS,RBBP7,MDC1,GTF3C3 |
| 9.676e-03 | -4.64 | DUF3456 | interpro domains | IPR021852 | 6 | 5 | 18521 | 5414 |
CRELD1,MZB1,CNPY3,CNPY1,CNPY4 |
| 9.676e-03 | -4.64 | Brix | interpro domains | IPR007109 | 6 | 5 | 18521 | 5414 |
RPF2,RPF1,BRIX1,PPAN,IMP4 |
| 9.676e-03 | -4.64 | ELO_CS | interpro domains | IPR030457 | 6 | 5 | 18521 | 5414 |
ELOVL4,ELOVL3,ELOVL6,ELOVL7,ELOVL1 |
| 9.676e-03 | -4.64 | TNF | interpro domains | IPR006053 | 6 | 5 | 18521 | 5414 |
FASLG,TNFSF15,TNF,LTA,LTB |
| 9.676e-03 | -4.64 | Fatty_acid_hydroxylase | interpro domains | IPR006694 | 6 | 5 | 18521 | 5414 |
CH25H,FA2H,FAXDC2,MSMO1,SC5D |
| 9.703e-03 | -4.64 | IRAK4 deficiency (TLR5) | REACTOME pathways | R-HSA-5603037 | 4 | 4 | 10285 | 3229 |
TLR10,IRAK4,TLR5,MYD88 |
| 9.703e-03 | -4.64 | Binding and entry of HIV virion | REACTOME pathways | R-HSA-173107 | 4 | 4 | 10285 | 3229 |
CXCR4,PPIA,CD4,CCR5 |
| 9.703e-03 | -4.64 | Neurotransmitter uptake and Metabolism In Glial Cells | REACTOME pathways | R-HSA-112313 | 4 | 4 | 10285 | 3229 |
GLUL,SLC38A1,SLC1A2,SLC1A3 |
| 9.703e-03 | -4.64 | Astrocytic Glutamate-Glutamine Uptake And Metabolism | REACTOME pathways | R-HSA-210455 | 4 | 4 | 10285 | 3229 |
GLUL,SLC38A1,SLC1A3,SLC1A2 |
| 9.718e-03 | -4.63 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043154 | 50 | 23 | 18204 | 5365 |
RAF1,TNF,DPEP1,GPX1,MMP9,LAMP3,VEGFA,PIH1D1,CDKN2D,SIAH2,SRC,AKT1,MIR17,CSNK2A1,IFI6,IGBP1,RNF34,MIRLET7B,SFN,DNAJB6,PAK2,CAAP1,KLF4 |
| 9.718e-03 | -4.63 | cell surface receptor signaling pathway via JAK-STAT | biological process | GO:0007259 | 50 | 23 | 18204 | 5365 |
SOCS5,STAT2,JAK1,GHR,STAT6,CCR2,PIAS1,CSF2,STAT5A,LEP,JAK2,IFNB1,CCL2,IL15,IFNG,NMI,STAT1,IL21,GH1,IL15RA,STAMBP,SOCS2,IFNAR1 |
| 9.718e-03 | -4.63 | cellular response to nerve growth factor stimulus | biological process | GO:1990090 | 50 | 23 | 18204 | 5365 |
GRIA1,CD2AP,ELAVL4,ACAP2,CBL,AKT1,NTRK2,RAB35,NTRK3,STMN2,ARF6,SHOC2,TAC1,UBE3A,USP8,NTF4,GAD2,TMEM108,EIF4A3,RAP1A,CSNK1E,ARPC3,EHD1 |
| 9.719e-03 | -4.63 | cell cycle phase transition | biological process | GO:0044770 | 159 | 61 | 18204 | 5365 |
CCND1,CDKN3,ANAPC2,PIAS1,AKAP8L,CCNB1,ARPP19,UBE2S,CCNA2,CKS2,CDK4,DNM2,PPM1D,PLCB1,CUL3,CDKN1B,CCNF,TAF2,RPL24,PIM2,EZH2,RB1,CUL2,MNAT1,CHMP2A,RBBP8,NDC80,CDKN1A,WNT10B,CKS1B,MTA3,BTN2A2,HINFP,FBXL7,EPS8,CDK6,UBE2A,PPP3CA,PPME1,CDC7,ACVR1B,RHOU,HSPA8,TPD52L1,CDK1,EIF4E,UBE2L3,MYC,CACUL1,ID4,TMOD3,CDC20,CCNI,CCND3,CCNY,MAP3K11,TAF10,ABCB1,LCMT1,CDC23,OVOL1 |
| 9.719e-03 | -4.63 | hexose metabolic process | biological process | GO:0019318 | 159 | 61 | 18204 | 5365 |
ATF4,SORD,PPARA,ENO2,LEP,PFKFB2,AKR1B1,PDHB,ATF3,FBP1,DLAT,AKT1,ENO1,SLC37A4,PGAM1,FUT1,SDS,PMM2,ERRFI1,KCNJ11,NPY1R,KBTBD2,PGM2L1,AKT2,CHST1,BRS3,LEPR,SLC25A1,G6PC3,PGM1,CRTC2,FPGT,TP53,FBP2,ADIPOQ,TNF,PIK3CA,LIPA,PGK1,MDH1,FUT8,GDPGP1,SLC35A2,G6PD,TKTL1,SLC25A12,PCK2,PDHA1,GHRL,BAD,OAS1,FUT9,SLC25A10,SLC25A11,CRY1,B4GALT1,GAPDH,FABP5,PC,INPPL1,GALE |
| 9.721e-03 | -4.63 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_melanoma_of_soft_parts-clear_cell_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_melanoma_of_soft_parts-clear_cell_sarcoma | 22 | 12 | 16828 | 4835 |
HRAS,KRAS,IDH1,SS18,EWSR1,KIT,CTNNB1,TP53,ETV6,TERT,SMARCB1,PTEN |
| 9.721e-03 | -4.63 | thymus | COSMIC cancer mutations | thymus | 22 | 12 | 16828 | 4835 |
KRAS,HRAS,SS18,GNAQ,FBXW7,AKT1,TP53,CTNNB1,MET,KIT,PTEN,PIK3CA |
| 9.721e-03 | -4.63 | malignant_melanoma_of_soft_parts-clear_cell_sarcoma | COSMIC cancer mutations | malignant_melanoma_of_soft_parts-clear_cell_sarcoma | 22 | 12 | 16828 | 4835 |
KRAS,HRAS,IDH1,SS18,EWSR1,TP53,CTNNB1,KIT,ETV6,TERT,PTEN,SMARCB1 |
| 9.725e-03 | -4.63 | HIVEP2 (HIVEP zinc finger 2) | protein interactions | 3097 | 25 | 13 | 19454 | 5460 |
CREBBP,RSPH1,TOP3B,YWHAG,EGR2,YWHAH,YWHAZ,FBXW11,HNRNPL,CAMK2G,BTG3,SKP1,VIRMA |
| 9.725e-03 | -4.63 | SYNPO2 (synaptopodin 2) | protein interactions | 171024 | 25 | 13 | 19454 | 5460 |
HSPA8,MAP1LC3A,SQSTM1,CDK6,STX7,ESR2,YWHAG,BAG3,MYC,ATG16L1,TP53,YWHAZ,VPS18 |
| 9.725e-03 | -4.63 | PLCB4 (phospholipase C beta 4) | protein interactions | 5332 | 25 | 13 | 19454 | 5460 |
RHOG,RHOB,CSK,DPP4,RAB11A,TP53,CDC42,MAP1LC3B,HNRNPL,RHOH,RHOJ,FBXO22,RAC2 |
| 9.725e-03 | -4.63 | DGKD (diacylglycerol kinase delta) | protein interactions | 8527 | 25 | 13 | 19454 | 5460 |
MYH2,FEZ1,KRAS,FXR2,ARF6,IGSF21,MYC,SLC6A4,H2BC9,RHOB,HAX1,TNFRSF14,PRKCA |
| 9.725e-03 | -4.63 | PAQR3 (progestin and adipoQ receptor family member 3) | protein interactions | 152559 | 25 | 13 | 19454 | 5460 |
ALCAM,SMURF1,MDM2,GNB1,STUB1,CYRIB,NRSN1,PIK3CA,PPARG,NFE2L2,RAD23B,PPARA,UBLCP1 |
| 9.725e-03 | -4.63 | GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) | protein interactions | 57678 | 25 | 13 | 19454 | 5460 |
TBC1D24,AKAP1,IDE,SRC,CLU,VIRMA,PSMC4,CIDEB,HNRNPC,MTCH2,FBXO7,GPAM,FIS1 |
| 9.725e-03 | -4.63 | SPIRE1 (spire type actin nucleation factor 1) | protein interactions | 56907 | 25 | 13 | 19454 | 5460 |
YWHAG,YWHAH,BCL7C,TOP3B,SFN,MTCH2,YWHAB,YWHAZ,FBXW11,ESR2,HNRNPL,TMOD3,ACTB |
| 9.725e-03 | -4.63 | GNA15 (G protein subunit alpha 15) | protein interactions | 2769 | 25 | 13 | 19454 | 5460 |
RGS2,MNAT1,CNR1,ADRB2,TTC1,HSPA8,APPBP2,OPRK1,WDCP,CXCR1,PRKCA,GRM2,OPRM1 |
| 9.725e-03 | -4.63 | STRADA (STE20 related adaptor alpha) | protein interactions | 92335 | 25 | 13 | 19454 | 5460 |
TIMM8B,CAB39,DYNLL1,RIGI,TIMM8A,CFTR,TIMM13,XPO1,FBXL19,PIP4K2C,PFDN6,STK11,HSP90AA1 |
| 9.725e-03 | -4.63 | FHIT (fragile histidine triad diadenosine triphosphatase) | protein interactions | 2272 | 25 | 13 | 19454 | 5460 |
SRC,MDM2,FHIT,YTHDF1,TRIM23,ARHGAP19,UBE2I,CTNNB1,GGH,TP53,DDIT4L,HSPD1,MTMR6 |
| 9.725e-03 | -4.63 | SECISBP2L (SECIS binding protein 2 like) | protein interactions | 9728 | 25 | 13 | 19454 | 5460 |
RAN,FBLN5,ZYX,VIRMA,PRRC2A,DYNLL1,PPP1CC,XPO1,INSYN2A,RAF1,PTAR1,LARP4B,DCAF4 |
| 9.725e-03 | -4.63 | ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4) | protein interactions | 22875 | 25 | 13 | 19454 | 5460 |
TMEM59,SOX2,TMBIM6,STX12,LGALS8,TMEM147,VAMP3,OPRL1,KRAS,ANKH,RAB14,LGALS3,LPAR1 |
| 9.725e-03 | -4.63 | SYN2 (synapsin II) | protein interactions | 6854 | 25 | 13 | 19454 | 5460 |
PRNP,POLL,GPM6A,SYN3,CHRM4,ARMC1,YWHAB,PSMC3,HAX1,YWHAZ,NOS1AP,YWHAG,TP53 |
| 9.725e-03 | -4.63 | PIK3AP1 (phosphoinositide-3-kinase adaptor protein 1) | protein interactions | 118788 | 25 | 13 | 19454 | 5460 |
NCK1,SYK,MYC,PIK3R1,TIRAP,RIGI,WNT7A,MYD88,PIK3AP1,TLR4,SOSTDC1,SARM1,TLR2 |
| 9.744e-03 | -4.63 | regulation of endoplasmic reticulum unfolded protein response | biological process | GO:1900101 | 29 | 15 | 18204 | 5365 |
AGR2,BAK1,UFL1,BAX,NCK1,COPS5,DNAJB9,HSPA5,BFAR,XBP1,PIK3R1,DDRGK1,TMEM33,BOK,PTPN1 |
| 9.744e-03 | -4.63 | respiratory chain complex IV assembly | biological process | GO:0008535 | 29 | 15 | 18204 | 5365 |
TIMM21,PET117,COX16,COX10,COA1,UQCC6,COX14,COX19,COX17,COA4,SLC25A46,BCS1L,COX20,TACO1,COA5 |
| 9.758e-03 | -4.63 | human chr17p13.1 | chromosome location | human chr17p13.1 | 138 | 43 | 26134 | 5823 |
TNFSF12,MFSD6L,ADPRM,STX8,RANGRF,MIR195,SLC13A5,MYH2,TMEM88,TNFSF13,MIR497,NLGN2,WRAP53,TXNDC17,TMEM107,RCVRN,MPDU1,TMEM256,MIR324,RPL26,RNASEK,PHF23,TMEM95,MYH1,SPDYE4,BORCS6,TMEM220,CCDC42,GABARAP,FXR2,SAT2,DVL2,XAF1,TRAPPC1,SPEM1,PLSCR3,TP53,KCTD11,CNTROB,DLG4,MED31,RNF222,VAMP2 |
| 9.769e-03 | -4.63 | myelin assembly | biological process | GO:0032288 | 24 | 13 | 18204 | 5365 |
CD9,CNTNAP1,PMP22,GNPAT,GPC1,MOBP,DICER1,TPPP,MIOS,TLR2,FIG4,CNTN1,MTMR2 |
| 9.769e-03 | -4.63 | myeloid dendritic cell activation | biological process | GO:0001773 | 24 | 13 | 18204 | 5365 |
PYCARD,BATF,PSEN1,CSF2,ITGB8,LTBR,TGFBR2,IRF4,TRAF6,IL4,RBPJ,NOTCH2,HMGB1 |
| 9.769e-03 | -4.63 | postsynaptic density organization | biological process | GO:0097106 | 24 | 13 | 18204 | 5365 |
NPTX1,DLG1,CNTNAP1,C1QL2,TMEM108,ARF6,LRRC4,NLGN1,HSPA8,C1QL3,NLGN2,PTEN,OPHN1 |
| 9.769e-03 | -4.63 | regulation of anoikis | biological process | GO:2000209 | 24 | 13 | 18204 | 5365 |
NTRK2,SNAI2,TLE1,ZNF304,PIK3CA,CEACAM5,CAV1,PTRH2,MCL1,PIK3R3,BRMS1,CRYBA1,SRC |
| 9.769e-03 | -4.63 | maturation of LSU-rRNA | biological process | GO:0000470 | 24 | 13 | 18204 | 5365 |
WDR12,RPF2,RPL7,RPL7L1,MAK16,RPL7A,NSA2,ZNHIT3,RPF1,FTSJ3,ZNHIT6,RPL35,RBM34 |
| 9.774e-03 | -4.63 | SRSF2 (serine and arginine rich splicing factor 2) | protein interactions | 6427 | 255 | 89 | 19454 | 5460 |
PNPO,UBE2H,RC3H2,PPP1CC,SUB1,DHPS,DEK,SRPK2,COPE,RPGRIP1L,TRIM27,MACROH2A1,CCNF,TUBA1B,EIF4A3,SCLT1,HEXIM1,METTL14,FBXW7,PRKCB,SIRT7,CDK12,SNRNP70,CSNK2A1,COPS5,CDC5L,ZBTB2,CWC15,CAND1,DSTN,PSMB1,CDK6,ALYREF,ILF2,CAMK1,UBE2B,TMEM126A,CCT5,PSMB10,VPS16,PSMA5,HUWE1,NEDD8,TTC4,POC1B,RIT1,BTF3,MYC,CUL2,SFN,CUL3,ESR2,SNRPD1,SNRPD2,SF3B4,TRA2B,SRSF2,UFL1,GPC1,HSPA8,SF3B1,YAF2,NUBP2,EP300,SNRPA,MAGOH,XPO1,DDRGK1,PRPF19,WWP2,RANGRF,SNRPD3,SNRPA1,EED,SRSF1,PHB1,PRCC,ZRANB2,VPS33A,EZH2,RAF1,SRSF4,HNRNPDL,PSMA1,KRAS,RUVBL1,EWSR1,THNSL1,HNRNPA2B1 |
| 9.777e-03 | -4.63 | membrane lipid metabolic process | biological process | GO:0006643 | 207 | 77 | 18204 | 5365 |
SGMS1,GALC,PIGC,CERS6,ELOVL3,GPAA1,ST6GALNAC3,OSBP,PPT1,HACD2,CERS2,PRKD3,HEXA,BAX,DEGS1,FA2H,PGAP4,PGAP2,PGAP3,SERINC1,GAL3ST1,ORMDL3,PLA2G15,FUT1,CERK,LARGE1,ITGB8,DPM2,ST3GAL4,ABCG2,SPTSSB,B3GALT1,GAL3ST4,HACD4,CLN8,B4GALT4,ELOVL7,HACD1,ELOVL6,SPHK2,PIGA,ACER3,SPTSSA,PIGW,B3GALT2,FUT9,SMPD2,HEXB,NEU1,ELOVL1,UGCG,ST3GAL1,ST3GAL5,AGK,ORMDL1,HTRA2,KDSR,SGMS2,CYP1B1,HACD3,ST8SIA5,KIT,PIGK,TECR,SLC30A5,B4GALT3,MGST2,VPS54,PIGY,ELOVL4,TLCD3B,ST8SIA4,ST3GAL2,B3GALT4,B4GALT6,B3GALNT1,CYP4F22 |
| 9.783e-03 | -4.63 | biogenic amine metabolic process | biological process | GO:0006576 | 89 | 37 | 18204 | 5365 |
SRM,AZIN2,DHPS,AZIN1,COMT,GDPD3,SULT1A3,GDE1,HAND2,DRD3,SULT1B1,HDAC6,OAZ2,MTPN,TGFB2,IDO1,MECP2,EDNRA,PDE1B,MOXD1,NR4A2,SLC6A3,GPR37,ASMT,SAT2,HNMT,RTL4,OAZ1,SLC1A1,PAOX,SNCB,ODC1,SAT1,DRD1,DBH,AANAT,OAZ3 |
| 9.783e-03 | -4.63 | pyrimidine-containing compound metabolic process | biological process | GO:0072527 | 89 | 37 | 18204 | 5365 |
UCKL1,UCK1,DCTPP1,RRM1,DCTD,APOBEC3B,ERH,SHMT1,PRPS1,DCK,TYMS,AK3,SMUG1,CMPK1,OGG1,CRMP1,APOBEC3G,STPG4,NME4,SLC19A3,THTPA,NT5C3A,ENTPD4,TKTL1,APOBEC3A,NME1,APOBEC3D,SLC19A2,DTYMK,UPRT,APOBEC3C,UCK2,APOBEC3H,UMPS,APOBEC3F,NME2,AK5 |
| 9.783e-03 | -4.63 | Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling | WikiPathways | WP3850 | 31 | 18 | 5310 | 1910 |
PRKAB1,EIF4E,PTEN,SMAD3,IGF1R,MAP1LC3A,PIK3CG,AKT1,IGF1,JKAMP,WASL,MSTN,SMAD2,EIF2B2,ILK,TRIM63,FBXO32,NFKB1 |
| 9.786e-03 | -4.63 | BCL2FAMILY | prints domains | PR01862 | 8 | 6 | 5227 | 1528 |
BAK1,BOK,MCL1,BCL2L1,BAX,BCL2A1 |
| 9.790e-03 | -4.63 | cellular response to transforming growth factor beta stimulus | biological process | GO:0071560 | 165 | 63 | 18204 | 5365 |
PDCD5,ID1,WNT7A,COL3A1,JUN,ITGB5,SRC,TGFB3,SMAD5,USP15,ITGB8,SMAD4,ACTA2,SMAD3,TGFB2,DLX1,XCL1,DUSP22,TP53,FERMT2,COL1A2,WNT2,STK16,HYAL2,IGF1R,SFRP1,CX3CR1,FLCN,CTSK,MIR142,YES1,SMAD2,MIR183,NDP,ACVR1,SOX9,MIR212,CLDN1,FMOD,FUT8,TGFBR2,PAK2,MIR130A,MIR21,CRKL,CHST11,MIR30A,SMAD1,SMAD9,CAV1,FOS,PML,TAB1,BMPR1A,CAV2,FURIN,PDE2A,ZYX,EID2,MEF2C,MSTN,CITED1,LPXN |
| 9.795e-03 | -4.63 | MCMBP (minichromosome maintenance complex binding protein) | protein interactions | 79892 | 151 | 56 | 19454 | 5460 |
GTF2I,STAU1,WDR55,RPA3,HSPA8,DDIT3,EP300,COMMD2,PTP4A2,RPA2,HEXIM1,EIF4B,PIH1D1,TPT1,ING5,PPP1CB,TCEAL1,ADRM1,TSN,CCNF,RPS20,MCM8,TLR9,NAPA,XPOT,UBE2H,DNAJB6,RIT1,MYC,CUL3,RNF40,MCM3,MCM4,KRAS,G3BP1,MCM6,CAPZA1,TRIP4,CCT8,RABGGTB,SKA3,EGLN3,DHX15,RPRD1A,PTPN1,FBXO32,ATP6V1A,PSMD7,DNAJC7,TSNAX,ATP6V1D,MOV10,YWHAG,YWHAH,ELOC,SUV39H1 |
| 9.804e-03 | -4.62 | regulation of glial cell proliferation | biological process | GO:0060251 | 42 | 20 | 18204 | 5365 |
PPP1CC,RNF10,IL6,MIR221,DICER1,UFL1,LTA,RB1,MIR146A,VEGFC,NF2,TNF,TSPO,CHRM1,KRAS,MECP2,IL1B,TP53,MIR222,CERS2 |
| 9.804e-03 | -4.62 | 'de novo' protein folding | biological process | GO:0006458 | 42 | 20 | 18204 | 5365 |
TOR2A,HSPA8,CHCHD4,HSPD1,ERO1A,SDF2L1,DNAJB4,FKBP1A,DNAJC7,HSPA5,PTGES3,CCT2,HSPA13,HSPE1,ST13,DNAJC2,TOR1B,SELENOF,HSPA14,FKBP1B |
| 9.804e-03 | -4.62 | regulation of alpha-beta T cell proliferation | biological process | GO:0046640 | 42 | 20 | 18204 | 5365 |
TWSG1,TNFRSF14,IL2RA,IL18,JAK2,VSIR,PRKCQ,FOXP3,IRF1,CD274,XCL1,IL12B,NDFIP1,IL23A,ARG2,CCR2,CD28,IL2,TGFBR2,CD81 |
| 9.804e-03 | -4.62 | somatic diversification of immunoglobulins | biological process | GO:0016445 | 42 | 20 | 18204 | 5365 |
SHLD1,MSH6,STAT6,NHEJ1,RNF8,CCR6,SWAP70,CD40LG,NBN,BATF,EXOSC3,SAMHD1,POLB,HMCES,MAD2L2,POLL,FOXP3,CTNNBL1,HSPD1,BCL6 |
| 9.821e-03 | -4.62 | MAD_homology_MH1 | interpro domains | IPR013019 | 8 | 6 | 18521 | 5414 |
SMAD3,SMAD5,SMAD9,SMAD1,SMAD4,SMAD2 |
| 9.821e-03 | -4.62 | Dwarfin | interpro domains | IPR013790 | 8 | 6 | 18521 | 5414 |
SMAD1,SMAD2,SMAD4,SMAD9,SMAD5,SMAD3 |
| 9.821e-03 | -4.62 | Proteasome_asu_N | interpro domains | IPR000426 | 8 | 6 | 18521 | 5414 |
PSMA6,PSMA5,PSMA1,PSMA4,PSMA3,PSMA2 |
| 9.821e-03 | -4.62 | SMAD_MH1_sf | interpro domains | IPR036578 | 8 | 6 | 18521 | 5414 |
SMAD1,SMAD5,SMAD3,SMAD4,SMAD2,SMAD9 |
| 9.821e-03 | -4.62 | Proteasome_alpha-type | interpro domains | IPR023332 | 8 | 6 | 18521 | 5414 |
PSMA1,PSMA5,PSMA6,PSMA2,PSMA3,PSMA4 |
| 9.821e-03 | -4.62 | SMAD_dom_Dwarfin-type | interpro domains | IPR001132 | 8 | 6 | 18521 | 5414 |
SMAD1,SMAD4,SMAD2,SMAD9,SMAD3,SMAD5 |
| 9.821e-03 | -4.62 | TRASH_dom | interpro domains | IPR011017 | 8 | 6 | 18521 | 5414 |
ZMYM6,ZMYM2,RPL24,ZMYM4,RSL24D1,ZMYM3 |
| 9.871e-03 | -4.62 | MHC_I_3 | pfam domains | PF16497 | 6 | 5 | 17795 | 5224 |
CD1E,CD1D,CD1B,CD1C,CD1A |
| 9.871e-03 | -4.62 | FA_hydroxylase | pfam domains | PF04116 | 6 | 5 | 17795 | 5224 |
FA2H,MSMO1,FAXDC2,SC5D,CH25H |
| 9.871e-03 | -4.62 | DUF3456 | pfam domains | PF11938 | 6 | 5 | 17795 | 5224 |
CNPY1,CRELD1,CNPY4,CNPY3,MZB1 |
| 9.871e-03 | -4.62 | Brix | pfam domains | PF04427 | 6 | 5 | 17795 | 5224 |
RPF1,IMP4,BRIX1,RPF2,PPAN |
| 9.920e-03 | -4.61 | ADCY3 (adenylate cyclase 3) | protein interactions | 109 | 58 | 25 | 19454 | 5460 |
IZUMO1,KLRC2,SLC4A8,TSPAN17,STOML3,CAMK2G,KRAS,ADRB2,RIGI,ANKMY2,RHOB,TLR9,CD79B,RAB35,STUB1,CIB2,MARCHF4,LHFPL1,HNRNPL,POPDC2,LGALS3,CLRN2,VIRMA,CAV1,APEX1 |
| 9.920e-03 | -4.61 | GMDS (GDP-mannose 4,6-dehydratase) | protein interactions | 2762 | 58 | 25 | 19454 | 5460 |
CCDC22,HNRNPD,UBE2H,RAB2A,CUL3,NTAQ1,BAG3,GMDS,EGLN3,MAT2B,TSR2,TNKS,RPA2,CAPN2,PIH1D1,NF2,NSFL1C,FBXW7,TNKS2,PRPS1,RPA3,ABCE1,PSMG4,HSPA8,SKA1 |
| 9.920e-03 | -4.61 | CD320 (CD320 molecule) | protein interactions | 51293 | 58 | 25 | 19454 | 5460 |
RIGI,TGFBR2,SRPRB,LITAF,SLC31A1,ARRDC3,CD83,RUSF1,LTBR,TSPAN3,FAM8A1,ACVR1,SLC22A8,IFNGR1,UBL4A,IL2RG,PRDX2,CD4,SLC1A1,NRSN1,KCNA2,TM4SF18,RHOG,CUL3,GPR17 |
| 9.920e-03 | -4.61 | GNPDA1 (glucosamine-6-phosphate deaminase 1) | protein interactions | 10007 | 58 | 25 | 19454 | 5460 |
PCNA,EWSR1,HAPSTR1,NUBP2,RPA3,PABPC1,VAMP8,DCTPP1,XPNPEP1,FGL2,ACCS,RPA2,PIR,GNPDA2,GNPDA1,CCNF,USP5,PNP,UMPS,COPS5,NT5C2,MOV10,TBCE,STK11,SMAD4 |
| 9.920e-03 | -4.61 | SNAP25 (synaptosome associated protein 25) | protein interactions | 6616 | 58 | 25 | 19454 | 5460 |
VAMP5,FBXO7,STXBP6,STX1A,NAPA,ZNF177,OSBPL8,KCNB1,STX5,OSBP,VAMP7,SNAPIN,STXBP1,VAMP2,STX12,PRKCA,HGS,UQCC2,GOSR1,KRAS,GPM6A,ZDHHC17,VAMP8,STX11,CPLX1 |
| 9.920e-03 | -4.61 | TAMM41 (TAM41 mitochondrial translocator assembly and maintenance homolog) | protein interactions | 132001 | 58 | 25 | 19454 | 5460 |
UBE2H,HTRA2,FAM174A,LAMP2,LAMP3,SPTAN1,RHOJ,TAMM41,APEX1,EGLN3,IL2RA,RPA2,TP53,HCST,MAP1LC3B,CDC42,MGARP,SLC15A1,HSCB,KRAS,TNF,TNFSF8,NDUFA4,RPA3,PRKCB |
| 9.931e-03 | -4.61 | TP53BP2 (tumor protein p53 binding protein 2) | protein interactions | 7159 | 236 | 83 | 19454 | 5460 |
SCNM1,CTNNA1,LURAP1,CCNF,PHF21A,UBASH3B,CSNK2B,GSK3A,ACTB,RPGRIP1L,SIAH1,YES1,VIRMA,CEP97,HOMER1,UBTD1,SFN,CREBBP,EMILIN1,MYC,PPP1CC,BAG3,CCDC85B,H2BC9,PRPF31,LMNB1,YWHAZ,GCC1,RGMA,ARHGEF6,ATPAF2,EP300,SQSTM1,SGF29,PTN,PPP1R2,KDM1A,MRPL20,TANK,LMO4,INSYN2A,PPP1CB,WWP1,FGFR1,RPA2,SCLT1,PARD6A,POLR2L,SUMO2,SUMO3,PLEKHF2,DCUN1D1,CDC5L,CNTROB,NDC80,WWP2,SETD5,NFKB1,PRPF19,CTNNB1,SIAH2,YWHAH,YWHAG,BECN1,CCDC92,BCL2L1,ZNF575,YWHAB,SSX2IP,MED4,RASSF8,ZYX,NAE1,BAG2,UBE3A,FAM168A,EFHC1,RIGI,PHF1,TP53,E2F4,DIRAS1,EEF1A1 |
| 9.934e-03 | -4.61 | regulation of vascular endothelial growth factor production | biological process | GO:0010574 | 61 | 27 | 18204 | 5365 |
MIR125A,IL1A,MIR107,MIR34A,MIR874,MIR15A,MIR195,MIR16-1,IL6,MIR132,MIR373,MIR106A,BRCA1,MIR504,IL1B,CYP1B1,MIR205,MIR20A,MIR17,MIR378A,MIR140,MIR361,ATF4,MIR146A,IL6ST,MIR147A,CCR2 |
| 9.936e-03 | -4.61 | ZWINT (ZW10 interacting kinetochore protein) | protein interactions | 11130 | 148 | 55 | 19454 | 5460 |
BECN1,NDC80,CENPW,EXOC1,TRIM34,HNRNPA1,NUF2,MDM2,EGLN3,TMPO,TSG101,YBEY,SKA3,TAF2,TP53,MRPL47,CENPM,SNAP29,TMEM126A,SPC24,ING1,ANAPC13,HNRNPF,STX11,LTBR,STX18,LMNB1,CCDC22,COL1A2,CCDC174,CCHCR1,DSN1,SYCE3,MLF1,SUGP1,PPP1CC,TYW3,BUB3,APEX1,CDC20,METAP2,CCNF,PHAX,EIF2B3,LIAS,MTMR6,BORCS6,SSR3,DGCR8,CLU,RPA3,SMG5,DDX5,TRIM5,MIS12 |
| 9.969e-03 | -4.61 | TRAPP complex | cellular component | GO:0030008 | 17 | 10 | 19108 | 5553 |
TRAPPC2L,TRAPPC6A,TRAPPC6B,TRAPPC1,TRAPPC3,TRAPPC10,TRAPPC4,TRAPPC14,TRAPPC3L,TRAPPC13 |
| 9.989e-03 | -4.61 | VCL (vinculin) | protein interactions | 7414 | 268 | 93 | 19454 | 5460 |
LRRC61,TRIM15,SPTAN1,SDHAF2,ATP6V1A,PDCD10,UBFD1,ASB7,AGR2,CTNNB1,YWHAG,XPO1,YWHAH,NDC80,CBLL1,RPS27A,SKA1,EWSR1,ZYX,MOB3C,HGS,PDHA1,CHMP4C,EZH2,TUBA1A,SPC24,ESR2,PPP5C,ACTB,CRMP1,YWHAZ,BRCA1,POMP,SFN,MYC,FBXO30,GINS3,TGFB1I1,STAU1,PPP2R3A,NUBP2,TXNL1,HSPA8,ISOC1,VAPB,GKAP1,H1-5,G6PD,CAV1,UBE2N,SSU72,CD274,DAG1,SNAP91,RIGI,ARF4,HSD17B10,PSME1,GNAI3,GNPNAT1,URM1,RPAP2,TNRC6C,TBK1,CEP97,SRC,UBA3,VIRMA,FERMT2,KCTD9,MSN,GSK3A,CTNNA1,CCNF,STK24,RC3H2,BICD2,DNAJC5,CEP85,C9orf72,HSPA5,PPP1R2,SIRT7,BAP1,RPA3,INPPL1,PRKCA,FGFR1,PICALM,JUP,RPA2,CFTR,LPXN |
| 9.994e-03 | -4.61 | cell body membrane | cellular component | GO:0044298 | 32 | 16 | 19108 | 5553 |
SLC12A2,KCND2,THY1,CX3CR1,SLC6A2,KCNB1,HPCA,ATP1A3,KCNA2,TACR3,KCNC1,SLC4A8,GRIA1,P2RY12,AMIGO1,SLC6A3 |
| 1.005e-02 | -4.60 | MH2 | pfam domains | PF03166 | 8 | 6 | 17795 | 5224 |
SMAD1,SMAD5,SMAD4,SMAD2,SMAD9,SMAD3 |
| 1.005e-02 | -4.60 | Proteasome_A_N | pfam domains | PF10584 | 8 | 6 | 17795 | 5224 |
PSMA5,PSMA2,PSMA4,PSMA3,PSMA6,PSMA1 |
| 1.005e-02 | -4.60 | MHC class I protein complex assembly | biological process | GO:0002397 | 6 | 5 | 18204 | 5365 |
CALR,TAPBP,B2M,TAPBPL,PDIA3 |
| 1.005e-02 | -4.60 | galactosylceramide biosynthetic process | biological process | GO:0006682 | 6 | 5 | 18204 | 5365 |
GAL3ST1,FA2H,B3GALT1,B4GALT3,B3GALT2 |
| 1.005e-02 | -4.60 | interleukin-10-mediated signaling pathway | biological process | GO:0140105 | 6 | 5 | 18204 | 5365 |
LILRB1,LILRB4,LILRA3,LILRA2,LILRA1 |
| 1.005e-02 | -4.60 | response to indole-3-methanol | biological process | GO:0071680 | 6 | 5 | 18204 | 5365 |
JUP,CTNNA1,CTNNB1,BRCA1,CYP1B1 |
| 1.005e-02 | -4.60 | amino acid neurotransmitter reuptake | biological process | GO:0051933 | 6 | 5 | 18204 | 5365 |
SLC6A1,SLC6A12,CLN8,SLC6A11,KCNJ10 |
| 1.005e-02 | -4.60 | response to heparin | biological process | GO:0071503 | 6 | 5 | 18204 | 5365 |
EXT1,EGR1,SFRP1,GPIHBP1,SOX9 |
| 1.005e-02 | -4.60 | eosinophil mediated immunity | biological process | GO:0002447 | 6 | 5 | 18204 | 5365 |
VAMP8,VAMP2,VAMP7,TRAF3IP2,CCL3 |
| 1.005e-02 | -4.60 | regulation of focal adhesion disassembly | biological process | GO:0120182 | 6 | 5 | 18204 | 5365 |
ARF6,MAPRE2,PIK3R1,DUSP3,IQSEC1 |
| 1.005e-02 | -4.60 | isocitrate metabolic process | biological process | GO:0006102 | 6 | 5 | 18204 | 5365 |
IDH3A,IDH3B,IDH1,IDH2,ACO2 |
| 1.005e-02 | -4.60 | protein targeting to vacuole involved in autophagy | biological process | GO:0071211 | 6 | 5 | 18204 | 5365 |
CLU,SMURF1,LAMP2,HSPA8,SQSTM1 |
| 1.005e-02 | -4.60 | snoRNA localization | biological process | GO:0048254 | 6 | 5 | 18204 | 5365 |
NOP58,PIH1D1,PRPF31,ZNHIT6,ZNHIT3 |
| 1.005e-02 | -4.60 | positive regulation of I-kappaB phosphorylation | biological process | GO:1903721 | 6 | 5 | 18204 | 5365 |
CX3CL1,AKT1,DDRGK1,TNF,CX3CR1 |
| 1.005e-02 | -4.60 | positive regulation of focal adhesion disassembly | biological process | GO:0120183 | 6 | 5 | 18204 | 5365 |
MAPRE2,ARF6,PIK3R1,DUSP3,IQSEC1 |
| 1.005e-02 | -4.60 | negative regulation of epithelial cell proliferation involved in prostate gland development | biological process | GO:0060770 | 6 | 5 | 18204 | 5365 |
EAF2,CDKN1B,WDR77,NKX3-1,STK11 |
| 1.005e-02 | -4.60 | gamma-aminobutyric acid import | biological process | GO:0051939 | 6 | 5 | 18204 | 5365 |
SLC6A6,NHERF1,SLC7A14,SLC32A1,SLC6A1 |
| 1.005e-02 | -4.60 | peptide antigen assembly with MHC class I protein complex | biological process | GO:0002502 | 6 | 5 | 18204 | 5365 |
TAPBPL,PDIA3,B2M,TAPBP,CALR |
| 1.005e-02 | -4.60 | regulation of protein K48-linked ubiquitination | biological process | GO:0061945 | 6 | 5 | 18204 | 5365 |
BIRC2,TRIM44,NMI,PPIA,GABARAP |
| 1.005e-02 | -4.60 | regulation of vascular associated smooth muscle cell dedifferentiation | biological process | GO:1905174 | 6 | 5 | 18204 | 5365 |
MIR221,MIR145,OLFM2,MIR214,MIR182 |
| 1.005e-02 | -4.60 | galactolipid biosynthetic process | biological process | GO:0019375 | 6 | 5 | 18204 | 5365 |
FA2H,GAL3ST1,B3GALT2,B3GALT1,B4GALT3 |
| 1.005e-02 | -4.60 | negative regulation of fibroblast growth factor production | biological process | GO:0090272 | 6 | 5 | 18204 | 5365 |
MIR152,RGCC,MIR205,MIR195,FGFR1 |
| 1.005e-02 | -4.60 | Late Phase of HIV Life Cycle | REACTOME pathways | R-HSA-162599 | 139 | 57 | 10285 | 3229 |
TAF9,CHMP2A,RPS27A,GTF2H5,NUP35,GTF2E1,VPS4B,CHMP4C,SUPT5H,NCBP2,CHMP2B,NUP153,NUP62,POLR2C,TSG101,VPS4A,GTF2H4,VTA1,XPO1,NUP107,GTF2F1,NUP42,POLR2I,VPS28,RAN,FURIN,NUP37,CDK9,ERCC3,SSRP1,GTF2B,TAF11,ELOC,POLR2G,SUPT4H1,GTF2A2,GTF2F2,POLR2F,TAF7,TAF10,TCEA1,UBB,RANBP1,GTF2H2,POLR2D,UBA52,POLR2L,CDK7,GTF2E2,TAF2,PPIA,POLR2B,MNAT1,CCNH,GTF2A1,CHMP5,NUP50 |
| 1.006e-02 | -4.60 | GPR52 (G protein-coupled receptor 52) | protein interactions | 9293 | 33 | 16 | 19454 | 5460 |
TMEM126A,SYNGR2,EMC10,YIPF4,YIPF3,SURF4,SIGMAR1,TMEM179B,FITM2,RETREG2,GJA1,GPR89A,LGALS3,VKORC1L1,MSMO1,TLCD4 |
| 1.006e-02 | -4.60 | ELMO3 (engulfment and cell motility 3) | protein interactions | 79767 | 33 | 16 | 19454 | 5460 |
RBM7,VPS18,SDC2,ELMO2,TUBA1A,FAM174A,ARL4A,TUSC2,FOXP2,ELMO1,RAC2,HSPA8,PCNA,UBE2S,EEF1AKMT3,SYNCRIP |
| 1.006e-02 | -4.60 | NSUN3 (NOP2/Sun RNA methyltransferase 3) | protein interactions | 63899 | 33 | 16 | 19454 | 5460 |
KLRC2,CTLA4,HEXIM1,RNF181,TOR1AIP2,TMEM106A,P2RY10,LRRTM1,KLRD1,SLC31A1,GRPR,PHB2,FTL,HSPD1,OSTM1,BSCL2 |
| 1.006e-02 | -4.60 | TMEM63C (transmembrane protein 63C) | protein interactions | 57156 | 33 | 16 | 19454 | 5460 |
ERG28,GPR89A,TMX2,VAMP3,STX8,ZNF787,STX7,HNRNPL,LGALS3,OSBP,YIPF3,FAM241A,TMEM199,NDUFB8,RNF181,SNX14 |
| 1.006e-02 | -4.60 | ZNF618 (zinc finger protein 618) | protein interactions | 114991 | 33 | 16 | 19454 | 5460 |
CUL3,MOV10,RAF1,UBL5,CSNK1E,NTAQ1,BRD3,CSNK1A1,TBC1D13,UBE2I,HSPA8,ZNF576,SNX24,ESR2,G3BP2,VIRMA |
| 1.006e-02 | -4.60 | ZDHHC20 (zinc finger DHHC-type palmitoyltransferase 20) | protein interactions | 253832 | 33 | 16 | 19454 | 5460 |
RAB5A,RAC2,RAB9A,HRAS,CD63,CAV1,CD151,KRAS,RHOJ,LAMP3,MBLAC2,LAMP2,RAB11A,TSPAN3,LAMTOR1,RHOB |
| 1.006e-02 | -4.60 | NKD2 (NKD inhibitor of WNT signaling pathway 2) | protein interactions | 85409 | 33 | 16 | 19454 | 5460 |
RCHY1,TNFRSF1B,CAV1,FXR2,ANAPC11,PRNP,FBXO7,YWHAG,YWHAH,CDKN1A,VDR,MARCHF5,ARMT1,YWHAB,YWHAZ,UBE2E3 |
| 1.006e-02 | -4.60 | TSEN34 (tRNA splicing endonuclease subunit 34) | protein interactions | 79042 | 33 | 16 | 19454 | 5460 |
AR,ARMCX3,FBXW11,TSEN54,CLP1,HNRNPD,PRKCB,GABPA,FBXW7,PITHD1,FBXO22,EYA3,ASF1A,FZR1,APEX1,RIGI |
| 1.006e-02 | -4.60 | EMID1 (EMI domain containing 1) | protein interactions | 129080 | 33 | 16 | 19454 | 5460 |
HSPA5,CDC5L,SELENON,YTHDF1,KRAS,KLHL25,CALU,DICER1,CRTAP,SDF2L1,P3H1,PPFIBP1,DDX39A,SAV1,USP13,TOP3B |
| 1.006e-02 | -4.60 | SDHAF3 (succinate dehydrogenase complex assembly factor 3) | protein interactions | 57001 | 33 | 16 | 19454 | 5460 |
GLRX5,NDUFAB1,ACP6,MTRF1,AUH,PMPCA,MTRES1,PDHA1,HINT2,SDHAF4,COX8A,GATD3,GFM1,SDHB,BOLA3,ATP5PF |
| 1.006e-02 | -4.60 | MATK (megakaryocyte-associated tyrosine kinase) | protein interactions | 4145 | 33 | 16 | 19454 | 5460 |
AR,CD36,CSK,MYC,AKT1,ILK,MET,HSP90AA1,BRCA1,FRS3,IGF1R,EWSR1,SRC,HSPA5,SMURF1,KIT |
| 1.006e-02 | -4.60 | Atp2a2 (ATPase, Ca++ transporting, cardiac muscle, slow twitch 2) | protein interactions | 11938 | 33 | 16 | 19454 | 5460 |
ATP5PO,YIPF5,ATP5F1A,SLC35E1,SLC35F6,ATP5PB,RABL3,PTDSS1,SEC22B,VTI1B,ATP5F1B,TMEM33,PHB2,STT3A,CCNF,PHB1 |
| 1.006e-02 | -4.60 | SAP30L (SAP30 like) | protein interactions | 79685 | 33 | 16 | 19454 | 5460 |
MXD1,HBP1,SAP30L,ZNF704,ING1,SAP30,HDAC3,RBBP7,TGIF2LX,RBBP4,ESR2,SIN3A,FEZ1,TGIF2,ING2,GATAD1 |
| 1.006e-02 | -4.60 | CHST5 (carbohydrate sulfotransferase 5) | protein interactions | 23563 | 33 | 16 | 19454 | 5460 |
DNAJB9,NOP9,SELENON,CXXC1,UTP25,C1QL1,TMX3,FKBP14,TMX4,TPPP,FUT8,TOR3A,DIPK1A,CFTR,CSGALNACT2,SEC62 |
| 1.006e-02 | -4.60 | MFSD12 (major facilitator superfamily domain containing 12) | protein interactions | 126321 | 33 | 16 | 19454 | 5460 |
GPR17,TP53,TOP3B,MAP1LC3B,TMEM14B,UPK1A,CRELD1,TSPAN15,SSMEM1,HAPSTR1,BSCL2,ADRB2,LPAR1,RIGI,OPRL1,SLC5A6 |
| 1.008e-02 | -4.60 | TRAF3-dependent IRF activation pathway | REACTOME pathways | R-HSA-918233 | 16 | 10 | 10285 | 3229 |
IFIH1,IRF7,CREBBP,EP300,IFNB1,TBK1,MAVS,SIKE1,IRF3,RIGI |
| 1.008e-02 | -4.60 | Formation of Senescence-Associated Heterochromatin Foci (SAHF) | REACTOME pathways | R-HSA-2559584 | 16 | 10 | 10285 | 3229 |
HIRA,H1-5,LMNB1,H1-1,ASF1A,UBN1,H1-3,HMGA1,TP53,RB1 |
| 1.009e-02 | -4.60 | Citrate cycle (TCA cycle) | KEGG pathways | hsa00020 | 30 | 17 | 7161 | 2463 |
PC,SDHC,IDH3B,DLST,SUCLG2,IDH2,PCK2,ACO1,PDHB,MDH1,ACO2,PDHA1,IDH1,OGDHL,DLAT,SDHB,IDH3A |
| 1.009e-02 | -4.60 | Citrate cycle (TCA cycle) | KEGG pathways | ko00020 | 30 | 17 | 7161 | 2463 |
PDHA1,IDH1,SDHB,IDH3A,OGDHL,DLAT,SUCLG2,IDH2,PCK2,ACO1,PC,SDHC,IDH3B,DLST,MDH1,ACO2,PDHB |
| 1.009e-02 | -4.60 | positive regulation of cell cycle phase transition | biological process | GO:1901989 | 118 | 47 | 18204 | 5365 |
DTL,MDM2,DDRGK1,UBE2E2,CDC16,CDC23,TMOD3,FGF10,RAB11A,CCND3,CDC20,ADAMTS1,CDC7,MIR495,CDK1,AKT1,VPS4B,PHB2,MTA3,SIN3A,MEPCE,ANAPC11,RRM1,WNT10B,TERT,PAGR1,MAD2L1BP,EZH2,RB1,MIR29A,MIR214,CUL3,SMARCD3,MIR208A,PLCB1,RGCC,MIR222,AIF1,MIR221,CCND1,LSM10,PPP1R10,CDK4,MIR519D,CCNB1,CDC73,CYP1A1 |
| 1.011e-02 | -4.59 | HIF-2-alpha transcription factor network | Pathway Interaction DB | hif2pathway | 34 | 19 | 2226 | 782 |
SLC11A2,FXN,ABCG2,EPO,POU5F1,BHLHE40,CREBBP,VEGFA,PGK1,EGLN3,MMP14,ELK1,APEX1,SP1,SLC2A1,ELOC,EIF3E,EGLN2,EP300 |
| 1.011e-02 | -4.59 | regulation of DNA binding | biological process | GO:0051101 | 75 | 32 | 18204 | 5365 |
NIBAN2,HEY2,PPARG,IFI16,CPNE1,PSEN1,CSNK2B,HAND2,JUN,NME1,HMGB1,CEBPG,TRAF6,TXN,TRIM6,RB1,SUMO1,MMP9,ZNF593,JAK2,PAX6,DDRGK1,IGF1,MAD2L2,EDF1,IFNG,KDM1A,MDFI,ZC4H2,TNKS,SUMO3,GTF2B |
| 1.013e-02 | -4.59 | circulatory system process | biological process | GO:0003013 | 508 | 174 | 18204 | 5365 |
CNR1,AR,CARTPT,SLC8A1,SOD1,ATP1A2,ATP1B1,HBB,OLR1,SLCO2B1,PRCP,UTS2,ADRB3,SLC4A8,GSK3A,SCPEP1,CHGA,RAMP3,GNB3,STAT1,NCALD,ATP8A1,OR51E2,ATP2B4,DRD3,ADRB2,SLCO3A1,BRS3,NPY,SLC6A1,SLC7A8,SLC5A6,GCLC,GPX1,OXTR,KCNMB1,SLC1A2,AGTRAP,NPR2,SLC1A1,SLC2A3,HRH2,LRP3,MAP2K3,ABCB1,ACTA2,SNX5,CYB5R3,GJC1,MIR21,ENPEP,SLC38A3,TACR1,KCNMB2,EMP2,ADM2,ABCC2,CAV3,UTS2R,CD36,CMA1,UCN,EDNRA,VSTM4,HTR1A,CAV1,SLC1A3,GPR37L1,VEGFC,FGF12,PPARA,E2F4,ADRB1,SNTA1,SMAD5,SOD3,APLN,ATP6AP2,HTR2A,REN,RASL10B,KCNJ2,PTP4A3,CDC42,IER3,FERMT2,SLC7A1,AKAP12,IMMP2L,FOXC2,SLC29A1,SLC12A2,KCNJ3,MIR17,PLN,SCN2B,SLC22A8,GJA1,CD38,GNA11,OPRL1,CYP11B1,GUCY1B1,KCNJ8,DRD1,TAFAZZIN,ASIC2,PDE2A,CXCL10,NHERF1,MAP2K6,NPPC,MIR23A,AGER,CXCR4,EMILIN1,KCNMA1,RGS2,CXCL12,RANGRF,DDAH1,CYP4F12,NPY1R,YES1,TFRC,SLC23A2,DBH,ATP1A1,COL1A2,AVPR1B,ROCK2,SCN3B,SMAD3,TNF,ADIPOQ,SLC2A1,CYP11B2,MIR153-1,CTNNBIP1,SLC15A2,TNNI1,PPARG,SLC16A1,ZNHIT1,KCND3,SLC6A6,VEGFA,SLC38A2,SLC38A1,BMPR2,MECP2,FABP5,MKKS,SLC6A4,EPO,LEP,ABCG2,ANGPT1,SRC,ADRA1A,ADORA1,COMT,EXT1,P2RY1,TACR3,LEPR,SOD2,SCN1B,ROCK1,TNNT2,ABCC5,PIK3CA,CACNB2,TCAP |
| 1.013e-02 | -4.59 | PACS2 (phosphofurin acidic cluster sorting protein 2) | protein interactions | 23241 | 20 | 11 | 19454 | 5460 |
YWHAB,YWHAZ,AGR2,WDR37,TRAF2,LEAP2,YWHAH,ANAPC15,ASPM,YWHAG,BIRC2 |
| 1.013e-02 | -4.59 | GJA3 (gap junction protein alpha 3) | protein interactions | 2700 | 20 | 11 | 19454 | 5460 |
GJB2,KLHL9,GJC1,PRMT2,MAP1LC3B,DDX39A,JUN,TRIM68,PSME2,GJA1,CAV1 |
| 1.013e-02 | -4.59 | PDHA2 (pyruvate dehydrogenase E1 subunit alpha 2) | protein interactions | 5161 | 20 | 11 | 19454 | 5460 |
MAP1B,SDHB,CUL3,COPS5,DLAT,CAND1,HSCB,PDHB,METTL14,DUSP21,MSMO1 |
| 1.013e-02 | -4.59 | BMP6 (bone morphogenetic protein 6) | protein interactions | 654 | 20 | 11 | 19454 | 5460 |
BMPR1A,SOSTDC1,APPBP2,SNX2,SNX1,SMAD5,BMPR1B,DDX39A,BMPR2,ACVR1,ANKRD50 |
| 1.013e-02 | -4.59 | ADORA1 (adenosine A1 receptor) | protein interactions | 134 | 20 | 11 | 19454 | 5460 |
UBAC2,GRM1,P2RY1,PELI3,GNAZ,GNAI2,ATXN1L,UFD1,TSHR,DRD1,GNAO1 |
| 1.013e-02 | -4.59 | CNTLN (centlein) | protein interactions | 54875 | 20 | 11 | 19454 | 5460 |
STAU1,PPP5C,NDC80,ATG101,SOX2,HDAC6,PRSS12,YWHAG,BRCA1,YWHAB,SP1 |
| 1.013e-02 | -4.59 | Cdc37 (cell division cycle 37) | protein interactions | 12539 | 20 | 11 | 19454 | 5460 |
HSP90AB1,HSP90AA1,FTSJ1,STN1,IKBKB,NFKBIL1,CFTR,TUBA1A,STX18,STUB1,WDR6 |
| 1.013e-02 | -4.59 | PPP1R3D (protein phosphatase 1 regulatory subunit 3D) | protein interactions | 5509 | 20 | 11 | 19454 | 5460 |
YWHAB,PPP1R3C,PYGB,YWHAZ,PPP1CC,XPO1,YWHAG,YWHAH,SFN,HSPD1,STBD1 |
| 1.013e-02 | -4.59 | OXT (oxytocin/neurophysin I prepropeptide) | protein interactions | 5020 | 20 | 11 | 19454 | 5460 |
CUL2,TXNDC17,HMGA1,TSPO,PREP,SHC1,NIF3L1,GPX1,OXTR,ESR2,CDK12 |
| 1.013e-02 | -4.59 | TTBK2 (tau tubulin kinase 2) | protein interactions | 146057 | 20 | 11 | 19454 | 5460 |
VIRMA,KLHL12,MAPRE1,FTL,PGRMC1,CSK,PTEN,CFTR,GNG2,COPS5,CSNK2A1 |
| 1.014e-02 | -4.59 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_chronic_myelomonocytic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_chronic_myelomonocytic_leukaemia | 35 | 17 | 16828 | 4835 |
STK11,SF3B1,RUNX1,KRAS,HRAS,CBL,IDH1,JAK1,EZH2,SRSF2,KIT,MET,FBXW7,IDH2,AKT1,PTPN11,JAK2 |
| 1.014e-02 | -4.59 | acute_leukaemic_transformation_of_chronic_myelomonocytic_leukaemia | COSMIC cancer mutations | acute_leukaemic_transformation_of_chronic_myelomonocytic_leukaemia | 35 | 17 | 16828 | 4835 |
EZH2,KIT,MET,SRSF2,PTPN11,JAK2,AKT1,FBXW7,IDH2,STK11,RUNX1,SF3B1,HRAS,KRAS,JAK1,IDH1,CBL |
| 1.014e-02 | -4.59 | genital_tract-extragonadal-germ_cell_tumour-teratoma | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-teratoma | 35 | 17 | 16828 | 4835 |
IDH1,CBL,KRAS,HRAS,SLC25A24,JAK2,DHX9,CTNNB1,PSMD6,KIT,FAM53B,TP53,SMARCB1,DPY30,PTEN,DICER1,TERT |
| 1.015e-02 | -4.59 | CEP131 (centrosomal protein 131) | protein interactions | 22994 | 195 | 70 | 19454 | 5460 |
SQSTM1,LCA5,RPA3,TEX264,TRIM52,KDM1A,MRPL12,BORCS6,TANK,ATG16L1,HAUS2,TMOD1,SCLT1,PTPN22,RPA2,PTEN,ANAPC2,PHF21A,GSK3A,DKK3,CTNNA1,TSSK1B,VIRMA,ESR2,DYRK1A,APEX1,DYNLL1,RPGRIP1L,AR,SFN,PYCARD,CEP85,CDC16,MAPRE1,YWHAZ,MYO6,LTBR,TRIM37,TMEM59,AURKAIP1,TOP3B,RAF1,CSNK1E,RHOBTB1,MOB3C,POLR2C,PNMA2,VPS33A,TUBB4B,KRT8,ARL10,FBXO32,PPP2CB,SLAIN2,SLMAP,PRNP,SPATA2,YWHAH,YWHAG,NDC80,WWP2,SAV1,YWHAB,MAP4,CAMSAP2,ANKRD50,DNAJC4,SSX2IP,MED4,TUBG1 |
| 1.017e-02 | -4.59 | Downstream signaling of activated FGFR2 | REACTOME pathways | R-HSA-5654696 | 30 | 16 | 10285 | 3229 |
FGF10,FGF17,FGF1,FGF7,PIK3R1,FGF3,FGF16,SHC1,FRS3,PIK3CA,FGF22,FGF23,PTPN11,KRAS,GAB1,HRAS |
| 1.017e-02 | -4.59 | Synthesis of active ubiquitin: roles of E1 and E2 enzymes | REACTOME pathways | R-HSA-8866652 | 30 | 16 | 10285 | 3229 |
UBE2H,UBE2S,UBE2A,UBE2W,UBE2G2,UBE2L3,UBE2K,UBB,RPS27A,UBA52,UBE2E3,UBE2B,USP5,UBE2D1,OTULIN,UCHL3 |
| 1.017e-02 | -4.59 | Recognition of DNA damage by PCNA-containing replication complex | REACTOME pathways | R-HSA-110314 | 30 | 16 | 10285 | 3229 |
POLD2,RPS27A,UBA52,RFC4,UBB,RPA2,POLE3,PCNA,POLE4,RFC3,RPA3,RFC2,UBE2B,POLD4,RFC5,DTL |
| 1.018e-02 | -4.59 | RRM_1 | pfam domains | PF00076 | 199 | 74 | 17795 | 5224 |
RBM34,HNRNPA2B1,ALYREF,RDM1,RBM41,CIRBP,RBM38,SRSF2,RBFOX2,SRSF10,TNRC6C,NONO,HNRNPC,SF3B6,PABPC5,UHMK1,ELAVL2,EIF4H,HNRNPA0,PSPC1,RBFOX3,RALYL,RBM17,EIF3G,RBM42,RBM5,SF3B4,CSTF2T,RBM22,SNRNP70,SNRPB2,MYEF2,SRSF12,RBM7,TIA1,ELAVL4,IGF2BP1,HNRNPD,HNRNPF,TRA2B,HNRNPH3,SNRPA,SART3,HNRNPDL,RBM18,SRSF8,HNRNPA1,GRSF1,BOLL,NCBP2,TRA2A,RBM27,CELF6,HNRNPL,SYNCRIP,EIF4B,SRSF7,HNRNPH2,HNRNPAB,EWSR1,RBM15B,RBM23,SRSF4,RBM12,RBMS2,POLDIP3,PPIL4,RBMX2,RBM3,ZCRB1,G3BP2,SRSF1,PABPC1,G3BP1 |
| 1.021e-02 | -4.58 | GIT1 (GIT ArfGAP 1) | protein interactions | 28964 | 142 | 53 | 19454 | 5460 |
SNRPA,RHOU,RPA3,ARHGEF6,TGFB1I1,SKP1,RGS2,NUCKS1,FBXW7,STAU1,NEK2,CDC42,LPXN,GIT2,PAK2,RPA2,PPT1,PSMC5,CCNF,RAN,LRIF1,APEX1,SRC,PTPRZ1,RHOJ,TAB1,HMOX2,KLHL1,NCKIPSD,ICAM1,RABGGTB,TFPT,PHYKPL,PFDN1,ZNHIT1,HSPA13,VPS33A,PPFIA2,NHERF1,PPFIA3,RAC2,EEF1AKMT3,YWHAG,YWHAH,EXOC1,TAX1BP3,UBXN6,FNDC11,MED4,KPNA1,RHOG,SMAD4,NCK1 |
| 1.021e-02 | -4.58 | VPS72 (vacuolar protein sorting 72 homolog) | protein interactions | 6944 | 142 | 53 | 19454 | 5460 |
SLC35A1,KPNA1,LHX2,HMGA1,MDFI,INO80E,CSNK2A1,MEAF6,PRNP,H2AZ1,IRF8,CBX3,DMAP1,H2BC1,ZNHIT1,MAX,ANP32A,ELF1,KRAS,RUVBL1,ANP32B,RUVBL2,EWSR1,BAG2,CHCHD4,STK11,RIT1,CSGALNACT1,MYC,MORF4L1,H2BC9,PSMD1,CCDC85B,ACTB,SNRNP40,MAD2L1,ESR2,ERH,ELK3,METAP2,TRIM24,KLF3,USE1,EIF2B3,PLAC1,ACTL6A,PAFAH1B1,ING5,KLF12,ATP6V1G1,CMAS,SLC39A9,EP300 |
| 1.024e-02 | -4.58 | GTF2H2 (general transcription factor IIH subunit 2) | protein interactions | 2966 | 44 | 20 | 19454 | 5460 |
ARHGAP25,COPS2,GTF2F1,CCNF,CLK4,ESR2,MNAT1,KRAS,HNRNPL,CCNH,HSPB8,GTF2E1,AR,CDK7,ERCC3,ATG16L1,GTF2H4,ERRFI1,GTF2H5,NUPR1 |
| 1.024e-02 | -4.58 | NKX3-1 (NK3 homeobox 1) | protein interactions | 4824 | 44 | 20 | 19454 | 5460 |
TOPORS,FAM136A,SP1,HSP90B1,CHPF,AR,FEM1B,TPT1,SP4,RPSA,WDR77,CCT7,MNAT1,TOP1,HNRNPA0,RPL37A,SP2,PEBP1,HIRA,TEX264 |
| 1.024e-02 | -4.58 | STYXL1 (serine/threonine/tyrosine interacting like 1) | protein interactions | 51657 | 44 | 20 | 19454 | 5460 |
ARMC8,HECTD1,SAMHD1,RPS29,SPTBN1,CCT5,PFDN5,CCT7,APEX1,RIGI,UNC45A,HNRNPL,TRIM54,ATXN10,SPTAN1,UMPS,MYO1B,AIP,EHD4,HSPD1 |
| 1.024e-02 | -4.58 | NAA35 (N-alpha-acetyltransferase 35, NatC auxiliary subunit) | protein interactions | 60560 | 44 | 20 | 19454 | 5460 |
PSMB10,VIRMA,DUSP19,RPL31,RPA3,LMBR1L,RPS3,PSMA6,NAA30,COX8A,VPS33A,SMNDC1,DNAJC2,AGR2,DRG1,RAF1,CALR,MYC,BTF3,CD2BP2 |
| 1.024e-02 | -4.58 | Nudt21 (nudix hydrolase 21) | protein interactions | 68219 | 44 | 20 | 19454 | 5460 |
YTHDF1,SNRPA1,LSM5,RPL7,RBM42,EIF3E,SLU7,PQBP1,EIF4A3,EXOSC4,CTBP1,RBM7,MAGOH,RPL10A,TXNL4A,UBL5,CPSF4,MREG,ESS2,SUV39H1 |
| 1.024e-02 | -4.58 | ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9) | protein interactions | 51114 | 44 | 20 | 19454 | 5460 |
KCNA2,TSPAN15,NRSN1,TMEM74,BSCL2,GGT7,SLC7A14,SLC7A1,CX3CL1,SYNE4,LPAR1,TSPAN5,CLRN2,APLNR,CREB3,TMEM59,FAM8A1,IL20RB,TMEM179B,TSPAN3 |
| 1.024e-02 | -4.58 | RFX3 (regulatory factor X3) | protein interactions | 5991 | 44 | 20 | 19454 | 5460 |
CDK20,SEC63,VIRMA,INPP5K,CREB1,EWSR1,RFX4,FHL3,RTCB,MINDY3,PKNOX1,MTA2,IRF6,DDX1,PABPC5,CFAP20,TMED4,MTCH2,SOX2,TRAF2 |
| 1.024e-02 | -4.58 | RNF139 (ring finger protein 139) | protein interactions | 11236 | 44 | 20 | 19454 | 5460 |
ERLIN2,CFTR,COPS5,HM13,EDEM1,INSIG2,CCDC47,UBE2H,EPHX1,SIGMAR1,TMEM165,FADS2,UBE2G2,ABHD13,TMUB1,ERLIN1,VDAC1,SPPL3,RNF5,CTSB |
| 1.024e-02 | -4.58 | CST8 (cystatin 8) | protein interactions | 10047 | 44 | 20 | 19454 | 5460 |
ARMC8,HSPA13,TMEM59L,SPCS3,DAG1,CDKN3,GSTK1,MGST2,B4GALT6,RANBP10,B4GALT4,B4GALT3,SQSTM1,RGS5,MKLN1,HS3ST1,TUBA1B,GID8,MAEA,SSBP1 |
| 1.024e-02 | -4.58 | SCD5 (stearoyl-CoA desaturase 5) | protein interactions | 79966 | 44 | 20 | 19454 | 5460 |
HSD17B11,SEC61B,DERL1,UQCRC2,SEC63,TNFSF8,OTULINL,SOX2,DNAJC25,PPP2R1A,SEC62,TMEM176A,KLRD1,ST7,ATG9A,PGRMC1,RAB5C,RPN1,GP9,ESYT1 |
| 1.024e-02 | -4.58 | OGFR (opioid growth factor receptor) | protein interactions | 11054 | 44 | 20 | 19454 | 5460 |
RPA2,SMAD4,EZH2,BRCA1,UBE2H,PIH1D1,TBK1,MYC,E2F4,CDK4,HSCB,PRKCE,EIF2B2,WASF3,RIGI,TRMT6,CCNF,FBXO32,HSPA8,MAGED2 |
| 1.025e-02 | -4.58 | SLC38A10 (solute carrier family 38 member 10) | protein interactions | 124565 | 61 | 26 | 19454 | 5460 |
EDEM2,CD1B,CLEC12B,TSPAN17,TSPAN15,FURIN,METTL14,CNPY3,MGARP,TOP3B,CCDC47,TP53,TOR1AIP2,RAMP3,DYRK1A,B4GAT1,ARMC6,SYNGR1,KCNA2,HAX1,THTPA,SMAD4,SPOP,SYP,HFE,PPIB |
| 1.025e-02 | -4.58 | GET1 (guided entry of tail-anchored proteins factor 1) | protein interactions | 7485 | 61 | 26 | 19454 | 5460 |
SPTSSA,ERG28,SLC15A1,RASGRP3,SLC7A1,KRAS,TOR3A,ABHD5,LPAR6,TFRC,SLC35E3,ITGB8,COMT,CAMLG,DUSP6,CCNF,COX20,TECR,APLNR,PLPP4,TM4SF19,HMOX2,ORMDL3,TMEM42,FAS,RIT1 |
| 1.025e-02 | -4.58 | NFYB (nuclear transcription factor Y subunit beta) | protein interactions | 4801 | 61 | 26 | 19454 | 5460 |
ELF1,XBP1,SMYD3,CCNA2,TP53,AGTRAP,CNTN2,CDK1,JUP,EP300,XRCC5,POLE4,KRAS,DRAP1,CTNNB1,CREBBP,NFYA,MYC,BRD3,OSGEP,SP1,RPS12,LDLR,CREB1,TAF11,TOP1 |
| 1.025e-02 | -4.58 | ARID5B (AT-rich interaction domain 5B) | protein interactions | 84159 | 61 | 26 | 19454 | 5460 |
KDM1A,HSCB,ASF1A,DVL2,KLF3,H2BC1,PARD6A,CCND1,ISG15,YIPF5,SOX2,HNRNPL,CAND1,RBBP4,EGLN3,VIRMA,ESR2,H2AZ1,PHF21A,CHORDC1,H2AC4,ZBTB38,HNF1B,RUNX1,AR,RACGAP1 |
| 1.026e-02 | -4.58 | cellular response to interleukin-2 | biological process | GO:0071352 | 8 | 6 | 18204 | 5365 |
STAT5A,JAK1,IL2RG,IL2,IL2RB,IL2RA |
| 1.026e-02 | -4.58 | canonical inflammasome complex assembly | biological process | GO:0140632 | 8 | 6 | 18204 | 5365 |
NLRP6,NLRP1,KCNJ8,ATAT1,PYCARD,NLRP3 |
| 1.026e-02 | -4.58 | interleukin-2-mediated signaling pathway | biological process | GO:0038110 | 8 | 6 | 18204 | 5365 |
IL2RG,JAK1,STAT5A,IL2,IL2RA,IL2RB |
| 1.026e-02 | -4.58 | neutrophil differentiation | biological process | GO:0030223 | 8 | 6 | 18204 | 5365 |
LBR,JAGN1,FOSL2,CSF2,DHRS7B,BAP1 |
| 1.026e-02 | -4.58 | negative regulation of cardiac muscle hypertrophy in response to stress | biological process | GO:1903243 | 8 | 6 | 18204 | 5365 |
PPARG,MIR25,MIR214,ATP2B4,LMNA,SMAD3 |
| 1.026e-02 | -4.58 | negative regulation of macrophage apoptotic process | biological process | GO:2000110 | 8 | 6 | 18204 | 5365 |
ST6GAL1,SELENOS,CCR5,IRF7,CCL5,MIRLET7B |
| 1.026e-02 | -4.58 | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway | biological process | GO:0007197 | 8 | 6 | 18204 | 5365 |
HRH3,CHRM5,CHRM1,CHRM3,CHRM4,OPRM1 |
| 1.026e-02 | -4.58 | positive regulation of toll-like receptor 3 signaling pathway | biological process | GO:0034141 | 8 | 6 | 18204 | 5365 |
TIRAP,PELI1,FLOT1,TRIM3,PTPN22,CAV1 |
| 1.026e-02 | -4.58 | galactosylceramide metabolic process | biological process | GO:0006681 | 8 | 6 | 18204 | 5365 |
GALC,GAL3ST1,FA2H,B3GALT2,B4GALT3,B3GALT1 |
| 1.026e-02 | -4.58 | regulation of iron ion transport | biological process | GO:0034756 | 8 | 6 | 18204 | 5365 |
IFNG,B2M,TF,HFE,ISCU,MIR210 |
| 1.026e-02 | -4.58 | 7-methylguanosine cap hypermethylation | biological process | GO:0036261 | 8 | 6 | 18204 | 5365 |
SNRPB,SNRPG,SNRPD2,SNRPD1,SNRPE,SNRPD3 |
| 1.026e-02 | -4.58 | righting reflex | biological process | GO:0060013 | 8 | 6 | 18204 | 5365 |
GLRB,GLRA1,USP46,ALDH1A3,NPSR1,SLC1A1 |
| 1.026e-02 | -4.58 | negative regulation of fibroblast apoptotic process | biological process | GO:2000270 | 8 | 6 | 18204 | 5365 |
SFRP1,CFDP1,PIK3CA,PIK3CG,MIR24-1,API5 |
| 1.026e-02 | -4.58 | negative regulation of cardiac muscle adaptation | biological process | GO:0010616 | 8 | 6 | 18204 | 5365 |
PPARG,MIR214,MIR25,LMNA,ATP2B4,SMAD3 |
| 1.026e-02 | -4.58 | putrescine metabolic process | biological process | GO:0009445 | 8 | 6 | 18204 | 5365 |
SAT1,ODC1,PAOX,AZIN1,SAT2,AZIN2 |
| 1.026e-02 | -4.58 | protein depalmitoylation | biological process | GO:0002084 | 8 | 6 | 18204 | 5365 |
ABHD10,LYPLA1,ABHD17A,LYPLA2,LYPLAL1,PPT1 |
| 1.026e-02 | -4.58 | inflammasome-mediated signaling pathway | biological process | GO:0141084 | 8 | 6 | 18204 | 5365 |
PYCARD,NLRP3,ATAT1,KCNJ8,NLRP6,NLRP1 |
| 1.026e-02 | -4.58 | siRNA processing | biological process | GO:0030422 | 8 | 6 | 18204 | 5365 |
TSNAX,HENMT1,TERT,TSN,DICER1,PRKRA |
| 1.026e-02 | -4.58 | protein retention in ER lumen | biological process | GO:0006621 | 8 | 6 | 18204 | 5365 |
KDELR1,PDIA2,KDELR2,RER1,OS9,GPAA1 |
| 1.034e-02 | -4.57 | NCOA3 (nuclear receptor coactivator 3) | protein interactions | 8202 | 192 | 69 | 19454 | 5460 |
TRIM21,EWSR1,UBE3A,MORC2,PHF1,EIF3E,PAX6,EGR2,SOX2,PPARA,PSMB9,JUN,SOX9,CSNK1E,VDR,TP53,EZH2,GTF2B,CTDSPL2,SMAD3,NUP35,FZR1,PGR,MIF,XPO1,YWHAH,NFKB1,ATG9A,IRF4,HNRNPD,AK2,IKBKB,SMAD4,PSMA3,NR1I3,RNF113A,EP300,RHOU,XRCC5,FOS,DCTN6,PIAS1,FBXW7,IQCK,SUMO1,SUFU,CCND1,PAX9,STAT6,KLF4,PPARG,PSMC5,ALB,PTEN,RAB28,NR1I2,VIRMA,ESR2,NR1H2,SMARCE1,AR,HNF1B,CREBBP,MYC,CDKN3,CUL3,SMAD2,SPOP,BRCA1 |
| 1.035e-02 | -4.57 | IFT20 (intraflagellar transport 20) | protein interactions | 90410 | 139 | 52 | 19454 | 5460 |
VPS26A,IFT25,NDC80,RASSF4,KXD1,MED29,LANCL2,PPP1R11,MED4,GNPAT,KIF3B,GSTCD,DNAJC1,DSTYK,DISC1,OXNAD1,IFT57,EXOC3,CD209,GPD2,IFT22,SLC25A11,SIKE1,RPS24,IFT52,BLOC1S2,KPNA2,USP30,PSMA1,TBCE,EMILIN1,EXOC5,REEP6,CCHCR1,IFT172,SEC61B,SERINC1,HOMER1,UBE2W,BET1,ATG16L1,NUP62,BORCS6,MED30,VPS18,WTAP,SCLT1,RARS1,EPHX1,HSDL1,LCA5,ZDHHC17 |
| 1.035e-02 | -4.57 | regulation of hormone levels | biological process | GO:0010817 | 543 | 185 | 18204 | 5365 |
SMAD4,PFKFB2,PPP3CA,SLC7A8,SELENOM,IL1B,SPP1,VAMP8,AANAT,CTSK,RETN,JAGN1,NPVF,UCP2,DIO3,ENY2,CHST9,OSBP,CAMK2G,HSD17B10,DHRS7,RAB3A,CNR1,CYP2C8,CYP1A1,CARTPT,CPE,GHRL,CYB5R4,SCPEP1,CHGA,PRKCE,CRY1,PRKCB,DIO2,CRHR1,BAD,JAK2,GNB3,CTSB,SULT1B1,SNAP25,HNF1B,CYP26A1,RASL10B,PCSK2,ATP6AP2,REN,CPLX3,IGF1R,CREB1,SFRP1,IL6,GNAO1,ACSL4,ACVR1C,CCL5,ASMT,KCNB1,DUOXA2,IDE,CCDC186,DHRS4,ENPEP,HADH,INHA,SRD5A3,GFI1,GNAZ,ILDR1,CYP2D6,ZMPSTE24,PLCB1,PCK2,SMAD2,TACR1,RAB1A,CMA1,FKBP1B,UCN,DKK3,EFNA5,SIN3A,FURIN,HTR1A,HSD17B6,AKR1B1,NKX3-1,SELENOT,STUB1,MME,CYP3A5,STX1A,HFE,KLK6,SCG5,RAB11B,RDH11,ATP1A1,RDH12,DIO1,CRHBP,CCN3,VAMP7,CLTRN,TNF,LHB,ADIPOQ,CYP17A1,CYP11B2,NDUFAF2,RAF1,F2,PICK1,VAMP3,DPP4,YIPF5,C2CD2L,ALDH1A3,VIP,HSD17B1,CYP21A2,SNAP23,GJA1,CFTR,CD38,CYP1B1,NLGN2,NFKB1,RDH10,SLC16A10,CHRM3,GNA11,SRI,HSD17B3,CYP11B1,DHRS11,VAMP2,SDR16C5,CYP2C9,SYBU,LRAT,PTPN11,ADH1B,RETSAT,HSD17B8,LRRC8A,LEP,UGT2A3,DHRS3,UGT1A1,CRABP2,KCNJ11,GABBR1,FGFR1,P2RY1,UQCC2,ADORA1,GHR,RAB8B,DYNLL1,TIAM1,HSD17B11,CHST10,IFNG,FZD4,NIBAN2,PPARG,OPRK1,SLC16A1,CRYM,PAPSS2,TSPO,OSM,ADH1A,SLC30A5,CPLX1,CYP2C18,C1QTNF1,AKR1C1,AKR1C2,FGF23,CYP27B1,EGR1,PNPLA4 |
| 1.037e-02 | -4.57 | YARS2 (tyrosyl-tRNA synthetase 2) | protein interactions | 51067 | 230 | 81 | 19454 | 5460 |
FASTKD5,HNRNPDL,ABHD10,KRAS,NUP42,ATP5F1D,CHDH,HNRNPK,PC,COX8A,HSPD1,PREPL,UQCC2,MRPL52,RBM3,BCKDK,GFM2,MRPL51,PDHA1,APOO,APOBEC3D,METTL15,MALSU1,RBM42,CAND1,LYRM2,PRNP,RHOH,MRPL50,PRR3,FAHD1,GATD3,SSBP1,HDHD5,RHOG,SNRNP70,NR2F6,MMUT,HNRNPA1,DDRGK1,GRSF1,UBXN6,CLPX,OGDHL,HSCB,OXCT1,SYVN1,HSPA8,GFM1,RPA3,ATPAF2,NGRN,AMACR,EXD2,LMNA,RPA2,MRPS18A,QRSL1,ACAA2,MRPL10,CRAT,CDC42,RBMS2,MRPL12,COQ8B,AGTRAP,CDC20,APEX1,CPT2,MRPL13,MCAT,RIT1,CIRBP,MRPL16,PCCB,MTG2,MYC,AUH,MRM2,CUL3,GSTK1 |
| 1.037e-02 | -4.57 | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity | molecular function | GO:0140933 | 10 | 7 | 18094 | 5411 |
NUDT1,NUDT7,NUDT5,DCP2,NUDT3,NUDT4,NUDT16 |
| 1.037e-02 | -4.57 | glutathione binding | molecular function | GO:0043295 | 10 | 7 | 18094 | 5411 |
PTGES,GSTM3,LANCL1,GSTM4,MMACHC,GSTM2,MGST2 |
| 1.042e-02 | -4.56 | TLC-dom | interpro domains | IPR006634 | 17 | 10 | 18521 | 5414 |
TRAM2,TLCD3B,TLCD2,TLCD4,TLCD1,TRAM1,CLN8,CERS6,CERS2,TRAM1L1 |
| 1.042e-02 | -4.56 | G-protein_gamma-like_dom | interpro domains | IPR015898 | 17 | 10 | 18521 | 5414 |
GNG3,GNG12,GNG13,RGS6,GNG7,GNG10,GNG2,GNGT2,GNG11,GNG5 |
| 1.042e-02 | -4.56 | GGL_sf | interpro domains | IPR036284 | 17 | 10 | 18521 | 5414 |
GNGT2,GNG2,GNG11,GNG5,GNG10,GNG7,RGS6,GNG3,GNG12,GNG13 |
| 1.044e-02 | -4.56 | Selenium Micronutrient Network | WikiPathways | WP1310 | 7 | 6 | 5310 | 1910 |
TXNRD3,TXN,SELENOW,MSRB1,TXNRD2,TXNRD1 |
| 1.044e-02 | -4.56 | Selenium Micronutrient Network | WikiPathways | WP1272 | 7 | 6 | 5310 | 1910 |
TXN,SELENOW,TXNRD3,TXNRD1,TXNRD2,MSRB1 |
| 1.046e-02 | -4.56 | USP48 (ubiquitin specific peptidase 48) | protein interactions | 84196 | 167 | 61 | 19454 | 5460 |
MCM3,AR,RPL7A,H1-1,UBE2H,SERPINH1,CMA1,LMNB1,BRCA1,MACROH2A1,VEGFA,ZNF330,UBB,SNRNP40,PPP1CB,RRAGA,SPTBN1,RPL27A,H1-5,FKBP10,GSTP1,EIF4B,H2BC11,RPA2,SSR1,DRD3,RPA3,BCL6,PDHB,UCHL3,NF2,MCMBP,CSNK2A1,HP,GRSF1,ZCCHC10,CDKN1B,PPIC,H2AC4,S100A8,SRP14,H2AZ1,SERPINC1,EEF1AKMT3,FBXO32,NCBP2,MDM2,WDR44,PRNP,SUMO2,SNX1,H2AX,TRAF2,PDHA1,CLPB,RPL3,RABGGTB,MMP9,FSTL1,H3C1,ADIPOQ |
| 1.048e-02 | -4.56 | SEH1L (SEH1 like nucleoporin) | protein interactions | 81929 | 136 | 51 | 19454 | 5460 |
TAB1,UBE2I,CCNF,BTF3,CXCL1,PSMD1,SEC13,MYC,AZGP1,TMEM209,HSPA8,NMRAL1,RPA3,UBE2M,KLC2,METTL14,FGFR1,LMNA,DCTN4,RPA2,CRYAB,SUMO1,LIAS,ATG16L1,CDC5L,CCT7,NUP35,EGLN3,KLK3,MIOS,NELL2,BGLAP,MSMB,BECN1,COPS5,DNAJB2,IFI16,RIGI,MRPL22,ADIPOQ,KRAS,NUP107,SEMG2,ACTR1B,CASTOR2,FAF1,NUPR1,GLE1,NUP37,NUP153,CCT5 |
| 1.048e-02 | -4.56 | AHCYL2 (adenosylhomocysteinase like 2) | protein interactions | 23382 | 136 | 51 | 19454 | 5460 |
PRNP,HNRNPL,CAV1,PTPN1,CLK4,RAB35,STYK1,DPP4,MAPK4,XPO1,COPS5,FGF12,RASL10B,CAMKV,KRAS,EPHA4,RPL17,PAK6,AHCYL1,ANP32B,NFKBIL1,RND3,SNX20,CSNK1E,ZNF263,JUN,ACTB,PSMD4,ZNHIT6,DOK4,SEC61B,CAB39,HEXIM2,SYT2,RHOB,PLEKHJ1,PIP4K2C,FBXW11,NTRK3,GREM2,SRSF2,BAP1,RBM23,RHOU,CLK1,SOST,FGFR1,HEXIM1,PIP5K1A,CPSF4,CDC42 |
| 1.051e-02 | -4.56 | TBC/RABGAPs | REACTOME pathways | R-HSA-8854214 | 45 | 22 | 10285 | 3229 |
GABARAP,RAB6B,ARF6,TBC1D17,GABARAPL2,RAB35,RAB4A,RAB5C,RAB11B,RAB6A,RAB33B,TBC1D16,RAB11A,TBC1D10C,TBC1D25,RAB8B,TBC1D24,RAB5A,OPTN,RAB33A,TBC1D13,MAP1LC3B |
| 1.053e-02 | -4.55 | EPC2 (enhancer of polycomb homolog 2) | protein interactions | 26122 | 64 | 27 | 19454 | 5460 |
EED,CSNK2B,LDLR,H2AZ1,LURAP1,VPS72,ESR2,MEAF6,PRNP,MYC,MORF4L1,KPNA1,RIT1,RUVBL2,HNRNPH2,HNRNPA2B1,FTL,KRAS,RUVBL1,MAX,ING5,PLAC1,DMAP1,MED23,KLF3,EZH2,H2BC1 |
| 1.053e-02 | -4.55 | KCTD15 (potassium channel tetramerization domain containing 15) | protein interactions | 79047 | 64 | 27 | 19454 | 5460 |
TUBA1A,SOX2,CCT5,TP53,TOP3B,GSTM2,NME1,PDIA6,RUVBL2,HSPA8,HSPA5,CA10,LRRTM2,TRIM63,RAB3B,CFL1,NTAQ1,YWHAB,REN,AP2A1,TRIM27,ZMYM2,CEP97,MYL12A,TUBB,KCTD15,KCTD3 |
| 1.053e-02 | -4.55 | SGO2 (shugoshin 2) | protein interactions | 151246 | 64 | 27 | 19454 | 5460 |
EGLN3,MAD2L1,SLAIN2,PREP,ALB,BRCA1,RGN,SPATS2L,PPP2R5A,COIL,LYPLA2,TUSC2,LYG2,HSCB,S100B,NLE1,EIF1AX,H2BC11,FEM1A,IER2,PPP2R1A,PLP2,SOX2,EXOSC8,CSNK1E,DUSP14,WDR83 |
| 1.053e-02 | -4.55 | KIF5C (kinesin family member 5C) | protein interactions | 3800 | 64 | 27 | 19454 | 5460 |
HOMER1,SYNE4,HNRNPL,TRAK2,AZIN1,YWHAB,YWHAZ,EXOC1,CSNK2A1,YWHAG,INSYN1,YWHAH,ANKMY2,TNFAIP3,NUPR1,KLC2,HEXIM1,METTL14,FGFR1,PPT1,EZH2,CFTR,SNAPIN,AURKAIP1,TP53,TANK,NUP62 |
| 1.053e-02 | -4.55 | S100A16 (S100 calcium binding protein A16) | protein interactions | 140576 | 64 | 27 | 19454 | 5460 |
MPST,TMEM177,OXCT1,HSPA8,CPNE2,RTN4,HNRNPA2B1,TCOF1,IDH3A,VAPB,STIM1,VAMP2,UBAC2,SOX2,ST7,UBA52,SEC22B,SUCLG2,ESR2,SNRPA1,MCPH1,MSN,CD274,TST,FBXO7,MOV10,PTDSS1 |
| 1.053e-02 | -4.55 | ITGA3 (integrin subunit alpha 3) | protein interactions | 3675 | 64 | 27 | 19454 | 5460 |
PDIA3,CALR,SCGB1D1,SMAD4,RHOB,CD9,LGALS8,EPHA2,RIT1,HRAS,EFNA3,CD151,RABIF,TOP3B,CFTR,ELK4,EZH2,MAP2K1,SFTPC,ITGB5,PEBP1,HSPD1,TMEM106B,RAB5A,KRAS,GPC1,RIGI |
| 1.053e-02 | -4.55 | PSKH2 (protein serine kinase H2) | protein interactions | 85481 | 64 | 27 | 19454 | 5460 |
NOP58,CACYBP,PPP5C,HSP90AB1,AIP,STUB1,TUBG1,DNAJC10,FKBP4,DNAJC7,HSP90AA1,MYC,KRAS,YTHDF1,NOP53,MRPL41,UNC119B,PTGES3,NDUFA4,RPAP3,RABGGTB,HADHA,LARP4B,RBFOX2,CDC42,MRPL10,CNP |
| 1.053e-02 | -4.55 | cellular response to amino acid starvation | biological process | GO:0034198 | 53 | 24 | 18204 | 5365 |
ATF4,TFEB,RNF167,ATF3,BECN1,SESN2,MIOS,EIF2AK2,FAS,IMPACT,DAP,KICS2,MAP1LC3A,FLCN,SLC38A2,EIF2S1,RNF152,SESN3,RRAGB,CDKN1A,SH3GLB1,SAR1B,UCP2,RRAGA |
| 1.053e-02 | -4.55 | positive regulation of TORC1 signaling | biological process | GO:1904263 | 53 | 24 | 18204 | 5365 |
SLC38A9,EP300,RRAGA,RRAGB,SEC13,FLCN,PIH1D1,LAMTOR2,STAMBPL1,LAMTOR1,SYK,LAMTOR3,KLHL22,CUL3,AKT1,MIOS,SRC,SESN2,RHEB,PIP4P1,CSNK1A1,TBK1,RNF167,GPR137 |
| 1.053e-02 | -4.55 | negative regulation of canonical NF-kappaB signal transduction | biological process | GO:0043124 | 64 | 28 | 18204 | 5365 |
ZMYND11,NKIRAS1,SNIP1,NFKBIL1,PYCARD,MIR497,CCDC22,TANK,LILRB4,MIR146A,RHOH,NFKBIA,NLRP6,ADIPOQ,STAT1,TMSB4X,CARD19,PPM1B,NKIRAS2,OPTN,TNFAIP3,MIR195,AZI2,GSTP1,MIR16-1,TLE1,MIR15A,OTUD7B |
| 1.053e-02 | -4.55 | regulation of B cell proliferation | biological process | GO:0030888 | 64 | 28 | 18204 | 5365 |
CD40,IL4,BCL6,MIF,SASH3,TLR9,CD38,CD81,MZB1,CTLA4,TLR4,PELI1,IL2,FCGR2B,TIRAP,CDKN1A,IL10,SLC39A10,MIR185,TYROBP,TICAM1,IL5,CHRNB2,IL13,TFRC,MEF2C,IL7,IL21 |
| 1.054e-02 | -4.55 | regulation of glucose transmembrane transport | biological process | GO:0010827 | 78 | 33 | 18204 | 5365 |
PTPN11,SLC25A27,CLIP3,GRB10,SELENOS,LEP,ARPP19,PIK3R1,AKT2,IL1B,CREBL2,PID1,AKT1,INPP5K,TERT,SLC1A2,GSK3A,MEF2A,PRKCB,GH1,YES1,MIR143,OSBPL8,MIR107,MIR223,PEA15,TNF,ADIPOQ,NFE2L2,IGF1,EDNRA,FABP5,RNASEL |
| 1.060e-02 | -4.55 | ZnF_UBP | smart domains | SM00290 | 11 | 7 | 9717 | 2575 |
BRAP,USP13,USP39,USP16,USP3,HDAC6,USP5 |
| 1.060e-02 | -4.55 | CDC25B (cell division cycle 25B) | protein interactions | 994 | 133 | 50 | 19454 | 5460 |
AGAP1,EIF4B,CDK1,KCTD12,CCNA2,SIPA1L1,SKP1,PHB2,SMC4,FAM53C,RTKN,CALU,EPHA2,TBC1D25,XPOT,DNAJC10,YWHAZ,FBXW11,AR,DEPDC1B,MAP3K21,CCNB1,SFN,FAM110B,MAT2A,CREBBP,SH3BP4,CDC20,CSNK2B,KIF1C,MSH6,SRSF12,MAPK1IP1L,TESK2,IGF1R,FHL3,CDK5,YWHAB,CAMSAP2,TIAM1,EDC3,YWHAH,YWHAG,CSNK2A1,XPO1,CDC5L,PGR,KCTD3,EIF4E2,WDR6 |
| 1.060e-02 | -4.55 | SPEN (spen family transcriptional repressor) | protein interactions | 23013 | 133 | 50 | 19454 | 5460 |
HMGA1,UBE2E2,RPL10A,EED,NCBP2,SOX2,MSX2,SOX9,TOP3B,SUPT5H,MTA2,RBPJ,RHOBTB1,EZH2,NFKBIL1,CBX3,PIR,BAG2,SCYL2,CAMKV,BPGM,H3C1,SERTAD1,RBBP7,ASF1A,TRIM37,RUNX1,RNF40,MYC,SP1,RBBP8,DCAF4,SRPK2,VIRMA,RBBP4,SNRNP40,PRDX3,CDK7,NOTCH2,RPA2,MED23,CTBP1,HSPA8,CLK1,NUP50,RPA3,NLE1,SIRT7,MBD3,STAU1 |
| 1.060e-02 | -4.55 | DHRS7 (dehydrogenase/reductase 7) | protein interactions | 51635 | 133 | 50 | 19454 | 5460 |
GRPR,NPTN,RTN4,DERL1,SCN1B,SYVN1,HSPA8,CHRNB2,TLR5,SSR1,VAPB,LMNA,ST7,SEC62,OTULINL,CNPY3,CLRN2,POPDC2,COPE,SEC61B,LMBR1L,LMNB1,SCN3B,SACM1L,SRPRB,KRAS,TSPAN17,TMEM268,GPM6B,TMT1A,IL20RB,CCR1,RPN1,STIM1,DNAJC25,NUP35,LMAN1,MARCHF4,DNAJC1,SPINT2,HSD17B11,PTPN1,KCNA2,TMEM30A,ESYT1,RHOG,LAMP3,RAB5C,LAMP2,DPP4 |
| 1.062e-02 | -4.55 | amine metabolic process | biological process | GO:0009308 | 98 | 40 | 18204 | 5365 |
DBH,AANAT,DRD1,OAZ3,SNCB,PAOX,SLC1A1,SAT1,INMT,ODC1,RTL4,OAZ1,SLC6A3,GPR37,HNMT,SAT2,ASMT,MOXD1,PDE1B,NR4A2,MECP2,EDNRA,TGFB2,IDO1,MTPN,SULT1B1,HDAC6,OAZ2,CHDH,DRD3,CYP1A1,GDE1,SULT1A3,HAND2,GDPD3,COMT,AZIN1,DHPS,SRM,AZIN2 |
| 1.067e-02 | -4.54 | Negative regulation of MAPK pathway | REACTOME pathways | R-HSA-5675221 | 40 | 20 | 10285 | 3229 |
PPP5C,DUSP9,YWHAB,PPP2R5A,DUSP6,DUSP1,PAQR3,PPP2CB,HRAS,KRAS,MAP2K1,RPS27A,PPP2R5E,UBA52,DUSP10,PPP2R1A,BRAP,PEBP1,RAF1,UBB |
| 1.071e-02 | -4.54 | synaptic cleft | cellular component | GO:0043083 | 22 | 12 | 19108 | 5553 |
NPTX1,LAMB2,LGI1,C1QL3,SLC1A1,C1QL2,CDH8,NLGN1,C1QL1,ACHE,PRSS12,CBLN1 |
| 1.071e-02 | -4.54 | mitochondrial outer membrane translocase complex | cellular component | GO:0005742 | 22 | 12 | 19108 | 5553 |
SAMM50,TOMM70,CHCHD3,APOO,TOMM22,TOMM40L,CHCHD6,TOMM7,TOMM20,TOMM6,MTX2,TOMM40 |
| 1.072e-02 | -4.54 | RNA 5'-end processing | biological process | GO:0000966 | 37 | 18 | 18204 | 5365 |
RAMAC,SNRPE,RPP25,RPP21,RPP14,SNRPB,SNRPG,NOP9,POP7,HSD17B10,SNRPD1,RPP25L,SNRPD2,CMTR1,SNRPD3,POP5,THG1L,CMTR2 |
| 1.072e-02 | -4.54 | cellular response to low-density lipoprotein particle stimulus | biological process | GO:0071404 | 37 | 18 | 18204 | 5365 |
CD81,TLR4,MIR146A,CD9,ADTRP,CDH13,TLR6,CD36,PPARG,FCER1G,TXNIP,MYD88,LDLR,AKT1,SOCS5,MIR20A,TICAM1,SYK |
| 1.072e-02 | -4.54 | response to lipoprotein particle | biological process | GO:0055094 | 37 | 18 | 18204 | 5365 |
FCER1G,TXNIP,MYD88,AKT1,LDLR,SOCS5,TICAM1,MIR20A,SYK,CD81,TLR4,MIR146A,CD9,ADTRP,CDH13,TLR6,CD36,PPARG |
| 1.072e-02 | -4.54 | peptidyl-proline modification | biological process | GO:0018208 | 37 | 18 | 18204 | 5365 |
PPWD1,NTMT1,FKBP1A,PPIL3,PPIG,FKBP4,PPIB,PPID,PPIH,CRTAP,FKBP1B,EGLN2,PPIC,P4HA2,PPIA,EGLN3,FKBP10,PPIF |
| 1.072e-02 | -4.54 | purine ribonucleotide transport | biological process | GO:0015868 | 37 | 18 | 18204 | 5365 |
SLC35B3,CALHM3,SLC25A42,ABCC5,CD47,SLC25A5,LRRC8A,LRRC8D,SLC25A31,ANKH,SHOC2,SLC25A17,SLC25A23,GJB1,LRRC8C,LRRC8B,SLC25A4,SLC25A24 |
| 1.073e-02 | -4.53 | UBE2U (ubiquitin conjugating enzyme E2 U) | protein interactions | 148581 | 130 | 49 | 19454 | 5460 |
F2,TRIM32,BFAR,TRIM23,CGRRF1,TRIM24,ALB,TRIM27,KLK6,TRIM46,TRIM54,HBB,TRIM68,PML,TRIM3,RNF10,RNF113A,PCGF2,TRIM5,SYVN1,RNF5,TTR,RNF41,VPS28,RNF11,RNF14,TRIM34,HP,MUL1,CBL,RNF139,SERPINC1,TSG101,RNF144B,TRIM15,PLG,TRIM35,MDM2,SERPINA3,SERPINA1,RNF181,TRIM63,TF,TRIM37,RBCK1,ANAPC11,PCGF6,RNF26,SERPIND1 |
| 1.073e-02 | -4.53 | DVL1 (dishevelled segment polarity protein 1) | protein interactions | 1855 | 130 | 49 | 19454 | 5460 |
PTRH2,GNAI3,KLHL12,CSNK1E,TOP3B,MAP2K3,SMAD1,HUWE1,SMAD4,SSX2IP,WWP2,CSNK2A1,XPO1,CTNNB1,CETN2,CEP19,SMAD3,SDC4,GJA1,KRT8,RB1,CTBP1,RPA2,WWP1,ANXA7,ATG16L1,DAAM1,DET1,KDM1A,MLH3,FBXW7,STAU1,TOMM20,DVL2,RPA3,GPHN,PSMA3,DCAF4,COP1,SMAD2,USP13,CIAO1,EPS8,BAG3,SNRNP40,HECW1,CTNNA1,RMDN3,PHF21A |
| 1.073e-02 | -4.53 | plasma membrane raft | cellular component | GO:0044853 | 114 | 45 | 19108 | 5553 |
NOS1AP,BMPR2,ADD2,KCNMA1,DAG1,CAV2,IGF1R,HTR2A,SMPD2,CHRNB2,TGFBR2,EMP2,SLC6A3,CORO1C,FASLG,ADRA1A,BVES,CTNNB1,CD36,CHRNA7,LRP6,EFNA5,BMPR1A,ATP2B4,CDH13,KCND2,CAV1,FLOT1,ADTRP,SLC2A1,RANGRF,CAV3,HDAC6,LCP2,SLC22A6,CBL,MLC1,SRC,ATP1A2,CTNNA1,CAVIN2,STIM1,JAK2,SPRED1,TFPI |
| 1.075e-02 | -4.53 | SRPK3 (SRSF protein kinase 3) | protein interactions | 26576 | 186 | 67 | 19454 | 5460 |
RPL37A,PRKRA,SF3B4,SNRPD1,PELP1,SRPK2,ZNF622,RPL7L1,RPF1,RPL13A,RPL26,FBXO7,SNRPB,RPF2,RPL7A,HSP90AA1,EXOSC1,NSA2,FTSJ3,CHTOP,ZNHIT3,CCDC86,SNRPA,RBM23,RFC4,NLE1,BRIX1,SRSF2,NOP53,STAU1,CDK7,RPL26L1,MFAP1,TFIP11,LUC7L3,USP39,MRTO4,KRR1,SRSF1,DKC1,DHX15,CDC5L,SURF6,CAND1,LYAR,TRA2A,MOV10,RBM17,KPNA1,SNRNP70,DROSHA,RPL3,MRPS18B,MYO1B,DHX9,NKRF,PPAN,SRSF4,RPL17,CDC40,H1-6,THRAP3,MAK16,RPL15,SF3B5,LLPH,RBM34 |
| 1.076e-02 | -4.53 | TRAM_LAG1_CLN8 | pfam domains | PF03798 | 17 | 10 | 17795 | 5224 |
TLCD2,TLCD4,TRAM1,CLN8,CERS2,CERS6,TRAM2,TRAM1L1,TLCD3B,TLCD1 |
| 1.076e-02 | -4.53 | G-gamma | pfam domains | PF00631 | 17 | 10 | 17795 | 5224 |
GNGT2,GNG13,GNG3,GNG10,GNG2,GNG12,GNG7,RGS6,GNG5,GNG11 |
| 1.076e-02 | -4.53 | TNF | pfam domains | PF00229 | 17 | 10 | 17795 | 5224 |
TNFSF10,TNF,LTA,CD40LG,LTB,TNFSF12,TNFSF15,TNFSF13,TNFSF8,FASLG |
| 1.076e-02 | -4.53 | thioredoxin-dependent peroxiredoxin activity | molecular function | GO:0140824 | 6 | 5 | 18094 | 5411 |
SELENOF,PRDX3,PRDX1,PRDX4,PRDX2 |
| 1.076e-02 | -4.53 | U1 snRNP binding | molecular function | GO:1990446 | 6 | 5 | 18094 | 5411 |
LEMD3,SNRPB,SNRPA,RBM23,SNRPD3 |
| 1.076e-02 | -4.53 | gamma-aminobutyric acid:sodium:chloride symporter activity | molecular function | GO:0005332 | 6 | 5 | 18094 | 5411 |
SLC6A11,SLC6A12,SLC6A6,SLC6A1,SLC6A8 |
| 1.076e-02 | -4.53 | porin activity | molecular function | GO:0015288 | 6 | 5 | 18094 | 5411 |
VDAC1,TOMM40L,BAK1,TOMM40,VDAC2 |
| 1.076e-02 | -4.53 | thioredoxin peroxidase activity | molecular function | GO:0008379 | 6 | 5 | 18094 | 5411 |
SELENOF,PRDX3,PRDX1,PRDX4,PRDX2 |
| 1.077e-02 | -4.53 | vulva | COSMIC cancer mutations | vulva | 46 | 21 | 16828 | 4835 |
SF3B1,RUNX1,GNAQ,IDH1,KRAS,HRAS,PTEN,PIK3CA,SLC17A5,CDKN2C,AKT1,JAK2,IDH2,PPP2R1A,FBXW7,CTNNB1,GNA11,MET,KIT,TP53,BRCA1 |
| 1.077e-02 | -4.53 | endometrium-carcinoma | COSMIC cancer mutations | endometrium-carcinoma | 46 | 21 | 16828 | 4835 |
DICER1,PTEN,PIK3CA,TERT,FGFR1,FBXW7,AKT1,JAK2,TP53,BRCA1,CTNNB1,MET,RB1,KIT,SRC,SF3B1,STK11,MSH6,PIK3R1,KRAS,HRAS |
| 1.077e-02 | -4.53 | peritoneum-mesothelioma | COSMIC cancer mutations | peritoneum-mesothelioma | 46 | 21 | 16828 | 4835 |
FBXW7,AKT1,PTPN11,JAK2,TP53,BRCA1,CTNNB1,KIT,MET,GNA11,RB1,SMARCB1,PTEN,PIK3CA,FGFR1,IDH1,KRAS,HRAS,SMAD4,GNAQ,STK11 |
| 1.077e-02 | -4.53 | NS-carcinoma | COSMIC cancer mutations | NS-carcinoma | 46 | 21 | 16828 | 4835 |
SF3B1,CDK6,NFE2L2,SRC,MAP2K1,CREBBP,KRAS,HRAS,SMARCB1,PTEN,EP300,CDC42,CDK4,PIK3CA,AKT1,IGF1R,CTNNB1,MET,KIT,TP53,BRCA1 |
| 1.078e-02 | -4.53 | KDM4C (lysine demethylase 4C) | protein interactions | 23081 | 67 | 28 | 19454 | 5460 |
TRIM21,RPL3,H3C1,HDAC3,TP53,SF3A1,EEF2,ACTN4,IDH2,PPARG,CTTN,DLST,EEF1B2,GATD3,MTAP,PRMT5,FBXO22,PNP,APEX1,VIRMA,HOMER1,ACO2,MOV10,SMCHD1,CSTA,NME2,BRD3,CA2 |
| 1.080e-02 | -4.53 | Toll-like receptor signaling | KEGG pathways | M00686 | 15 | 10 | 7161 | 2463 |
NFKB1,IRAK4,TLR4,MYD88,IKBKB,TAB2,TLR2,TRAF6,NFKBIA,TAB1 |
| 1.080e-02 | -4.53 | Toll-like receptor signaling | KEGG pathways | hsa_M00686 | 15 | 10 | 7161 | 2463 |
NFKB1,IRAK4,TLR4,IKBKB,MYD88,TAB2,TLR2,TRAF6,NFKBIA,TAB1 |
| 1.080e-02 | -4.53 | phosphorus metabolic process | biological process | GO:0006793 | 1707 | 545 | 18204 | 5365 |
ATP5F1B,NUDT2,HYCC1,PGAP2,PLSCR3,SRPK2,RPIA,PDE1A,MAP2K3,DUSP3,ATP5MG,OSBP,PAK6,UAP1,PDHB,SULT1A3,LDHA,NDUFA1,GDPD3,PDE8A,PTPN22,PXYLP1,PGAM1,FMO1,SEPHS1,ABHD14B,FAM20C,OLA1,PLA2G15,DYRK1A,MAP3K14,SLC19A3,PRKCB,PPP1CC,MAP2K1,CTBP1,SNRK,IDH1,CTTNBP2NL,TLR7,DNPH1,PPTC7,HYCC2,BECN1,TNNI3K,ATP1B1,ETNK2,CDK7,ATP1A2,NDUFA2,DLG1,MVD,HCST,GPX4,PTPN5,DHRS7B,CSNK2A1,TECR,PLA2G12A,ATP5PF,BAZ1B,CSNK1E,PPP2R5E,MTMR6,IGF1R,CREB1,ALDH1L1,IER3,PLA2G4B,DAPK1,DUSP19,SLC25A1,SOCS2,PGAP3,G6PC3,CASK,FMO2,DNAJC30,PTP4A2,FITM2,DYRK2,HACD2,TLR3,NUDT18,EPHA4,MMUT,PDE7A,NDUFA12,SOCS4,NDUFB7,MAP3K12,CTDSP2,GDE1,CDK5R1,GLYAT,STK3,NDUFS8,ISYNA1,ATP5F1A,INPP5K,HTR2A,RPS6KA4,CDK1,PIM2,LDHB,NME4,PTPRZ1,ACOT6,SMPD2,SLC20A1,COQ8B,PPP1CB,SOCS3,ATP6V1A,PRDX4,TAB1,SSH3,TNKS,DCTPP1,CSNK1G3,AK2,ATP5PO,PDP2,IGFBP3,PLPP6,SLC19A2,DTYMK,MTM1,SOCS5,NUDT5,NDUFC2,ABHD12,IL4,CDK8,NEK9,PRKX,MAP3K11,SHMT1,PLAAT3,RAF1,DUSP18,ROCK2,PPT1,EPHB6,ATP5MK,FITM1,FBP1,GTPBP1,ABHD5,CAB39,MAPK10,DUSP10,DPAGT1,ORMDL3,EPHA2,MTMR12,CDK5,BCKDK,CERK,ILK,GUCY1B1,FBXW11,TAFAZZIN,ANKH,NUDT3,TYMS,OGG1,STRADB,FDFT1,PTPMT1,ELOVL1,INPPL1,TOP1,FRA10AC1,ELOVL6,CDK9,SPHK2,DCTD,SDHB,PIP4K2C,FUT8,CSNK2B,PLSCR1,ACOT8,MAPKAPK3,PPM1D,PRKCA,DDR1,PDHA1,STK38L,ACVR1,IL21,NDUFV2,MAP3K3,FHIT,NEK7,CNP,PGAP4,CSGALNACT1,GNPTG,PIGC,GNAI3,STK4,IDO1,HADHA,CCL11,IP6K1,PTPN11,PIP4P1,INPP4A,SORD,UGDH,TSSK1B,ENO2,CDK6,TLR4,MPP1,PLPP4,FGFR1,MTHFD2L,PTPRQ,NDUFAB1,TMEM38B,ACSS2,PTPN1,HSPA8,GPHN,ATP5F1E,AK3,ITK,FAR2,HEXB,PLAAT5,OSBPL8,ADCK1,CLN8,HINT1,GNPDA2,IKBKB,PLPPR1,GAPDH,PTPN4,LIPA,NUDT7,CSNK1A1,PAPSS2,PPP2R3A,TAMM41,BPNT2,NQO1,GNPDA1,STK24,SDHC,PDE9A,PPP2R1A,PRKCQ,HDHD5,SLA2,IRAK4,TNFAIP8L3,CAMKV,NPR2,DUSP14,INPP5E,PRPS1,ATP5PD,CLK4,SGMS1,UCP2,UQCC3,CRYL1,PRKD3,PIK3R3,CAMK2G,GK5,KARS1,PIP4P2,MAPK4,DUSP26,PFKFB2,FKRP,SDHAF2,CLP1,PPP3CA,ACP2,CDC7,DYRK1B,AKT1,ATP5MC1,SLC25A10,AKR1A1,GSK3A,FN3KRP,PRKCE,ADCY2,BAD,DCK,ACACA,PIP5K1A,CDKL2,PPP3R2,CKB,PPP5C,JAK2,PTEN,ACP5,NR1H2,PLA2G5,PCSK9,CDK12,CTDSP1,TGFBR2,STK26,PLAA,TP53I3,PAK2,RPE,PNPO,RIOK2,TOLLIP,MET,COQ8A,DOLK,EIF2AK2,KIT,NANP,NDUFB6,CSK,ABHD6,AGPAT1,PTP4A3,CDIPT,BGLAP,SEPHS2,RAB23,FBP2,NIM1K,ACVR1C,STOML2,ACSL4,ABHD4,FGR,SUCLG2,RNASEL,OXSR1,GNPNAT1,SULT1B1,IMPA2,UPRT,GPD2,DAPK3,PAK5,UCK2,PPP2CB,GGPS1,PPP1R12A,AKT2,COPS2,PNP,AGPAT5,DLAT,AKT3,UHMK1,ENO1,ACP6,NUDT19,DUSP21,PNPLA8,PIGW,NUS1,NDUFS3,PRKAG1,PC,ADSS2,GMDS,GFPT1,ADCY3,REXO2,ENTPD3,DCAKD,DSTYK,ELOVL7,PHKG1,MDH1,CDKN3,OCRL,SRD5A3,TNIK,LPCAT3,PSKH1,ORMDL1,PCK2,PLCB1,ADM2,PPP2R5A,PRPSAP1,GUK1,MFN1,JAK1,OGDHL,GPAM,ABHD16B,PRKAB1,DUSP1,YES1,NT5C2,SARM1,UCKL1,GPAA1,DUSP22,WEE2,NME2,PRDX6,DPM2,NDUFA5,GFUS,STK11,STK38,SYK,GK2,PPAT,ACVR1B,CISH,PCYT1B,TESK1,ATP5F1D,EXTL2,NDUFB5,PIGA,THTPA,CACNB4,BMPR1B,CLPX,NPPC,MAP2K6,CCL2,UGP2,DUSP6,MAPKAPK5,UCK1,NUDT9,PDE2A,PTHLH,CSNK1A1L,PICK1,BPGM,ACAT1,TRIB1,TBK1,UMPS,CDK4,NUDT12,DMPK,CD38,SGMS2,NEK2,PPM1M,DUSP9,TPST1,FAM20B,UBLCP1,CHKB,ENTPD4,SELENOI,G6PD,TLR2,TESK2,PGM1,ROCK1,STK16,SERINC1,DLST,GNPAT,BIRC5,NMRK1,PAFAH1B1,ELOVL3,NUDT4,PIK3CA,ATP5PB,ADK,NDUFS2,GMPS,MAP3K21,FIG4,PLCB2,COX11,ATP5MC3,PIK3CG,PDE4B,VAC14,LEP,IDH2,MTMR2,NME1,NDUFB10,SRC,NT5C3A,CDK20,VRK1,CLK1,BMPR2,HMGCS1,PPM1K,SAMHD1,PRRT1,CMPK1,SMUG1,UBASH3B,NDUFB4,IL15,PPM1G,NUDT16,SACM1L,BMPR1A,MECP2,ALPL,FABP5,PPM1B,RRM1,HACD1,PGK1,ELOVL4,NTRK3,SLC52A3,AK5,NTRK2,PIGY,NDUFB8,MGAT1,PTDSS1,PGS1,CAMK1,RAN,PIK3R1,CDK17,PIK3R2,SBK2,AGK,SLC30A5,STYK1,NDUFS6,YWHAZ,PIGK,PRKACB |
| 1.083e-02 | -4.53 | Lung fibrosis | WikiPathways | WP3624 | 63 | 32 | 5310 | 1910 |
CCL3,CCL5,CCL11,SERPINA1,IL13,TIMP1,TERT,CCR2,CCL2,SFTPA1,IL12B,IL6,IGF1,IL5,GREM1,NFE2L2,CSF2,CXCL8,CCR3,TNF,MMP9,ELMOD2,STN1,SPP1,MT2A,MECP2,SFTPC,FGF7,CMA1,IL4,IL1B,FGF1 |
| 1.085e-02 | -4.52 | RBM27 (RNA binding motif protein 27) | protein interactions | 54439 | 127 | 48 | 19454 | 5460 |
NUP50,EP300,BAP1,RPA3,STAU1,SUMO1,ATG16L1,HEXIM1,RPA2,SGTA,MRPS28,EZH1,MRPL53,CCNF,TNPO3,VIRMA,SRPK2,SPCS1,RNASEH1,AR,MYC,UBE2H,YWHAZ,RC3H2,BAG2,ZC3H11A,TRIM37,CHCHD2,IKZF5,NDUFA2,H2AJ,KBTBD4,RAF1,UBL4A,PDHA1,ACTR2,CBX3,NUP35,EGLN3,CDK9,THOC1,DDRGK1,HNRNPA1,NDC80,MED4,POU5F1,SNRNP70,H2AC4 |
| 1.085e-02 | -4.52 | SLC12A7 (solute carrier family 12 member 7) | protein interactions | 10723 | 127 | 48 | 19454 | 5460 |
CAV1,TMEM237,STX6,DIRAS3,RHOH,ARF6,MARCHF4,RAC2,GJA1,RAB35,HRAS,RHOG,TMBIM6,RAB5C,DPM2,RIGI,FLOT1,TMED7,SRPRB,GJB1,KRAS,TMEM147,TSPAN17,RND3,TMEM204,RAB4A,NRN1,OR4N2,VIRMA,CLRN2,POPDC2,RHOJ,LGALS3,LGALS8,RHOB,LAMTOR1,RAB11A,RAB2A,STX7,SLC31A1,RAB9A,CYP2C18,RAB5A,RHOU,GP9,DIO3,CDC42,RND2 |
| 1.085e-02 | -4.52 | CYP51A1 (cytochrome P450 family 51 subfamily A member 1) | protein interactions | 1595 | 127 | 48 | 19454 | 5460 |
RPA2,FTH1,PRDX3,OTULINL,TPT1,PGRMC1,TMUB1,HSCB,SLC31A1,HADHA,DERL1,RTN4,RPA3,CGRRF1,SNX14,ATG101,MYC,CLRN2,YES1,TXNDC12,EIF4A2,SEC61B,LMBR1L,CCNF,LGR4,MAP1LC3B,DNAJC25,DDX39A,CCDC47,TBK1,RAF1,PSEN1,SRPRB,TGFBR2,KRAS,CCNY,TSPAN17,TMEM268,TMT1A,PAQR9,TM4SF18,DEGS1,ADIPOR2,MARCHF4,SPINT2,HSD17B11,HRAS,KCNA2 |
| 1.087e-02 | -4.52 | negative regulation of response to endoplasmic reticulum stress | biological process | GO:1903573 | 45 | 21 | 18204 | 5365 |
DNAJB9,LPCAT3,CREB3,SGTA,NCK1,SELENOS,SYVN1,UFL1,AQP11,PTPN1,TXNDC12,NR1H2,TMBIM6,BCL2L1,SVIP,CLU,DDRGK1,XBP1,USP14,HSPA5,BFAR |
| 1.087e-02 | -4.52 | acidic amino acid transport | biological process | GO:0015800 | 45 | 21 | 18204 | 5365 |
CLN8,GJA1,SLC7A14,NHERF1,SLC6A6,SLC6A1,SLC7A11,KCNJ10,SLC25A12,SLC32A1,GRM1,SLC1A1,GRM2,SLC38A2,NTRK2,SLC1A2,KCNJ8,VPS54,ARL6IP5,PSEN1,SLC1A3 |
| 1.087e-02 | -4.52 | negative regulation of gliogenesis | biological process | GO:0014014 | 45 | 21 | 18204 | 5365 |
DRD3,RB1,MIR146A,DUSP10,GPR37L1,NF2,DICER1,RNF10,NOG,F2,ID4,CTNNB1,NKX6-2,DLX1,TP53,MECP2,LDLR,MIR181C,CERS2,NR2E1,TSPO |
| 1.087e-02 | -4.52 | spliceosomal snRNP assembly | biological process | GO:0000387 | 45 | 21 | 18204 | 5365 |
SRSF10,CD2BP2,SRSF12,SNRPB,LSM2,SNRPE,SMN1,SNRPG,LSM4,PRMT5,TSSC4,SNRPD2,WDR77,COIL,SART3,PRPF31,PRPF19,SNRPD1,GEMIN7,GEMIN8,SNRPD3 |
| 1.087e-02 | -4.52 | cell surface pattern recognition receptor signaling pathway | biological process | GO:0002752 | 45 | 21 | 18204 | 5365 |
PRKCE,IRF3,TLR5,PIK3AP1,TLR4,TMEM126A,OAS1,LY96,TBK1,TICAM1,MBL2,NFKBIA,TICAM2,IRAK4,TIRAP,NMI,TLR2,CD14,MYD88,TRAF6,FCN2 |
| 1.087e-02 | -4.52 | TIMM9 (translocase of inner mitochondrial membrane 9) | protein interactions | 26520 | 47 | 21 | 19454 | 5460 |
PARL,MPST,PTGES3,OXCT1,AGK,KRAS,DHX9,PRDX6,SFXN1,TIMM8B,BAD,RIT1,HTRA2,CTSA,TIMM8A,BAG3,TIMM29,TIMM13,COX5A,SEC22B,TIMM10 |
| 1.087e-02 | -4.52 | PDXK (pyridoxal kinase) | protein interactions | 8566 | 47 | 21 | 19454 | 5460 |
RABIF,ESR2,RIGI,DYRK1A,G6PD,EIF4E,TAX1BP1,SNX2,CAND1,HNRNPL,THUMPD1,LIG3,SOD1,RPA3,MDH1,OAT,CFTR,COPS5,TP53,CUL3,MOV10 |
| 1.087e-02 | -4.52 | C14orf180 (chromosome 14 open reading frame 180) | protein interactions | 400258 | 47 | 21 | 19454 | 5460 |
HAS3,CLEC7A,VSIR,CYBC1,REEP4,TMEM167B,MGST3,TIMMDC1,FAM174A,TM4SF19,ASZ1,PPP1CC,PPP1CB,AQP3,TMEM31,TMEM106C,NCR3LG1,TMEM14B,PDZK1IP1,MFSD14B,ZDHHC15 |
| 1.087e-02 | -4.52 | SCOC (short coiled-coil protein) | protein interactions | 60592 | 47 | 21 | 19454 | 5460 |
CCHCR1,TRAPPC6A,TRMT112,MAPRE1,SCHIP1,RBBP8,GCC1,RPS6KA4,SNAPIN,HMGA1,DDIT4L,DOK5,ATG16L1,MYC,CUL3,NRBF2,SSNA1,BLOC1S2,PSMC5,SIKE1,FEZ1 |
| 1.087e-02 | -4.52 | CKS2 (CDC28 protein kinase regulatory subunit 2) | protein interactions | 1164 | 47 | 21 | 19454 | 5460 |
SSBP1,CDK5,FZR1,CDK9,CDC20,LDHB,CCNB1,CKS1B,UBXN6,CCNA2,CDKN1A,IKZF5,GMNN,CFL1,EEF1A1,CDK1,CKS2,CDKN1B,HSP90AA1,CDK12,LACC1 |
| 1.087e-02 | -4.52 | TRIM59 (tripartite motif containing 59) | protein interactions | 286827 | 47 | 21 | 19454 | 5460 |
TP53,UBE2W,CLDN4,MRPL12,NRM,ABHD5,CSGALNACT2,SEC22A,YWHAZ,PPM1B,PKNOX1,RAD23B,KPNA1,RHOU,MACROH2A1,PTEN,GPX4,CDK5,VTI1B,ESR2,MDM2 |
| 1.087e-02 | -4.52 | CABLES1 (Cdk5 and Abl enzyme substrate 1) | protein interactions | 91768 | 47 | 21 | 19454 | 5460 |
VPS33A,TDRD7,RHOB,CDK12,AKT1,TOP3B,TP53,ZCCHC10,CDK7,EXOSC8,CDKN1A,KRAS,FBXO22,RHOJ,RHOH,CDK9,CDK5,AKAP1,ALB,ANAPC2,RAC2 |
| 1.089e-02 | -4.52 | NADH dehydrogenase (ubiquinone) activity | molecular function | GO:0008137 | 34 | 17 | 18094 | 5411 |
NDUFC2,NDUFS8,NDUFS2,NDUFA12,NDUFB4,NDUFV2,NDUFB6,NDUFS3,NDUFA5,NDUFA1,NDUFA4,NDUFB10,NDUFS6,NDUFB5,NDUFB8,NDUFA2,NDUFB7 |
| 1.089e-02 | -4.52 | - | gene3d domains | 3.30.1330.30 | 15 | 9 | 14470 | 4137 |
GADD45G,PELO,NHP2,GADD45A,RPS12,RPL7A,GADD45B,SECISBP2L,ETF1 |
| 1.093e-02 | -4.52 | RNA export from nucleus | biological process | GO:0006405 | 81 | 34 | 18204 | 5365 |
NUP62,XPO1,SMG5,THOC2,NUP107,HNRNPA1,XPO5,XPOT,DDX39A,MAGOH,ENY2,THOC6,POLDIP3,NCBP2,PHAX,MAGOHB,DDX39B,NXT2,THOC1,EIF4E,EIF4A3,FYTTD1,ALKBH5,RAN,ALYREF,NXT1,GLE1,CHTOP,HNRNPA2B1,ZC3H11A,RBM15B,THOC3,NUP153,CASC3 |
| 1.093e-02 | -4.52 | positive regulation of cytokine production involved in immune response | biological process | GO:0002720 | 81 | 34 | 18204 | 5365 |
SASH3,SYK,IL18,MIF,NLRP3,MYD88,TRAF6,BCL10,HTR2A,LILRB1,IL1B,IL4,KIT,PYCARD,CD81,TLR4,TNFRSF14,TLR7,RIGI,TICAM1,MAVS,SPHK2,TLR3,DDX1,XCL1,LACC1,RSAD2,CLEC7A,SEMA7A,B2M,TRAF2,CD36,IL6,TRIM6 |
| 1.095e-02 | -4.51 | SORBS3 (sorbin and SH3 domain containing 3) | protein interactions | 10174 | 183 | 66 | 19454 | 5460 |
APEX1,SCNM1,TRIM27,ALB,SYP,ATOSB,TRIM23,CCDC22,NCKIPSD,CCHCR1,ANAPC15,BAG3,OIP5,INPPL1,DVL2,TXNDC17,FAM53C,PAK2,PAK5,ATG16L1,FBXL19,CCNH,CFTR,CDK7,PPP1R18,CPNE1,SYNCRIP,GYS1,PPFIA3,GLRA1,NCK1,CBL,NAB2,CDC23,FNDC11,USP2,SETD5,GAS8,HNRNPF,ZBED1,KRAS,HNRNPK,WASL,PHF1,FLOT1,HNRNPDL,ENKD1,AKT2,ZBTB25,CDKN2C,EFHC1,CPNE2,KLHL15,ZC4H2,KLHL26,HGS,PARM1,TOP3B,IMP3,FASLG,ADORA1,E2F4,PNMA5,KIAA0408,TULP3,SPG21 |
| 1.096e-02 | -4.51 | ZNF622 (zinc finger protein 622) | protein interactions | 90441 | 124 | 47 | 19454 | 5460 |
ATG16L1,CDC42,RPA2,HECTD1,RPA3,LCA5,YAF2,PPP1R2,UFL1,HSCB,STAU1,UNC45A,BRIX1,FTL,TMED5,PRPF31,FTSJ3,DCAF4,PSPC1,ZNF330,SEC61B,MACROH2A1,ZNF622,RPL10,ATP5PB,STIM1,TUBB4B,DNAJC2,SRP72,RIGI,WWP2,FAM20C,DDRGK1,UBFD1,ATP6V1D,PTPN1,SRP14,MRTO4,KRR1,MYBL2,RPS16,DNAJC1,FZR1,CGAS,TMPO,RBM42,G6PD |
| 1.098e-02 | -4.51 | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | 60 | 26 | 16828 | 4835 |
NF2,JAK2,FBXW7,KIT,MET,TP53,BRCA1,PTEN,NTRK3,FGFR1,CREBBP,KRAS,SMAD4,AKT1,PTPN11,CTNNB1,RB1,TSHR,SMARCB1,PIK3CA,PIK3R1,MSH6,HRAS,RUNX1,SUFU,STK11 |
| 1.099e-02 | -4.51 | MED11 (mediator complex subunit 11) | protein interactions | 400569 | 70 | 29 | 19454 | 5460 |
MED23,CDK8,POLR2D,POLR2G,POLR2C,MED31,MED9,MED30,FBXL19,CFTR,KRAS,SGF29,FBXW7,TRIP4,MED13L,MED21,MED10,MED27,MED29,MED4,BRD3,RIT1,PRDX1,MED22,POLR2I,MED17,CNTROB,POLR2B,GTF2B |
| 1.099e-02 | -4.51 | IL6ST (interleukin 6 cytokine family signal transducer) | protein interactions | 3572 | 70 | 29 | 19454 | 5460 |
KRAS,RIGI,IL6,JAK1,PIK3CG,PARM1,SOCS3,IL6ST,CDC42,KCNIP3,RHOJ,CDK9,JAK2,SGTA,IL2RA,RAC2,CNTFR,RHOG,RHOB,SHC1,ZDHHC15,PIK3R1,PYCARD,VAMP5,TLE1,RAB11A,PTPN11,OSM,AR |
| 1.099e-02 | -4.51 | CD9 (CD9 molecule) | protein interactions | 928 | 70 | 29 | 19454 | 5460 |
RPA3,HRAS,CD63,TCOF1,FLYWCH2,MID1IP1,TSG101,CLN8,RBBP7,KIT,CAVIN2,ALCAM,THRAP3,ADRB2,CD36,CD38,DDX39A,HBEGF,CD81,CD59,RPA2,SDCBP,CD46,PSMD14,MAP2K1,CHRNB2,PRKCA,SERPINH1,NSA2 |
| 1.099e-02 | -4.51 | AAMP (angio associated migratory cell protein) | protein interactions | 14 | 70 | 29 | 19454 | 5460 |
MAP1LC3B,GABARAPL2,TULP3,HEXIM1,MMADHC,HSPA8,MKLN1,EP300,NKAPD1,ARGLU1,PSEN2,BHLHE40,SSRP1,KRAS,FXR2,XPO1,SUB1,DHPS,PDCD4,UBE2H,DICER1,RNF128,INPP5K,CCNF,RSRC1,PHB1,DKC1,RPL10,FZR1 |
| 1.099e-02 | -4.51 | PDS5B (PDS5 cohesin associated factor B) | protein interactions | 23047 | 158 | 58 | 19454 | 5460 |
EZH2,CBX3,CYB5B,NUPR1,KBTBD4,CD80,H3C1,G3BP1,RAD21,RPL31,PCNA,HAPSTR1,DDX23,H2AC4,BRD3,LAMP2,DDRGK1,RPL35A,OPRL1,CD274,EED,RAC2,RPA2,FAM234A,RND2,HCST,CDC42,CFTR,NFIL3,NPTN,SLC15A1,STK38,COIL,WFDC5,RPA3,CXCR4,SIRT7,HSPA8,RHOB,H1-1,MYC,SCN3B,VAMP5,GPR17,PRPF31,SPINDOC,FBXO22,APLNR,MAD2L2,VIRMA,APEX1,CCNF,SCN2B,LMBR1L,ZNF330,TUBA1B,CHRM4,EIF2S2 |
| 1.099e-02 | -4.51 | NRIP1 (nuclear receptor interacting protein 1) | protein interactions | 8204 | 158 | 58 | 19454 | 5460 |
OAZ1,NR0B1,PKNOX1,BRCA1,PSMD1,GPRASP3,AR,CEP70,CCDC85B,SCG3,RORB,ESR2,VIRMA,NR1H2,FBXO22,UBE2I,SESTD1,HECTD1,CTBP1,PPARG,CREBZF,SPTBN1,PIAS1,LDOC1,HSPA5,HDAC3,HDAC5,SF3B1,TNNC2,TNFRSF14,AGR2,CSNK2A1,XPO1,YWHAH,TRIM8,HNRNPL,SPPL3,SCG2,SNX1,RXRG,KLHL7,FEZ1,CDK8,VPS33A,PLAAT3,ARPC3,TRAF2,JUN,PPARA,TULP3,VDR,TP53,ZNF821,HUWE1,TRIM37,ZNF365,CLPB,S100B |
| 1.101e-02 | -4.51 | Histone_H2A/H2B/H3 | interpro domains | IPR007125 | 40 | 19 | 18521 | 5414 |
H2AC4,H2AX,MACROH2A2,MACROH2A1,H2AC7,H2BC14,H2BC1,H2AC1,H2AC14,H2BC11,H2BC17,H2BC12,H2AZ2,H2AC6,H2AC25,H2AZ1,H2BW1,H2BC9,H2AJ |
| 1.104e-02 | -4.51 | positive regulation of transmembrane transport | biological process | GO:0034764 | 214 | 79 | 18204 | 5365 |
NOS1AP,AZIN1,PIK3R1,CFTR,G6PD,AZIN2,CREBL2,GSTO1,AMIGO1,OPRK1,ATP1B1,F2,CCR2,STIM1,ARPP19,MIR21,PSEN1,COX17,CXCL10,NHERF1,NPSR1,PPP3R2,CCL2,CAV1,NFE2L2,ACTN4,TMSB4X,EDNRA,SLC38A1,MIR210,DRD1,KCNIP2,TERT,NDUFA4,PLP1,SRI,OSBPL8,FGF13,AKT2,KCNJ2,PPP3CA,STAC3,AKT1,CA2,GSTM2,TRPC1,PTPN11,TESC,CLIP3,THY1,ADRB2,APLNR,CACNB2,CXCL9,IGF1,KCNC1,MIR223,ADIPOQ,RNASEL,CX3CL1,CACNB3,ABCB1,CHP1,IFNG,XCL1,BAX,SCN1B,ATP1B3,GH1,VMP1,MEF2A,SLC1A2,MIR1-1,BAK1,CLTRN,KCNMB1,CXCL11,LACRT,IL13 |
| 1.105e-02 | -4.51 | OASL (2'-5'-oligoadenylate synthetase like) | protein interactions | 8638 | 221 | 78 | 19454 | 5460 |
NOC4L,IMP4,MRPS17,RIGI,NKRF,CCT8,RPL3,LLPH,EXOSC3,RBM34,MLLT11,CCR1,JCHAIN,SART3,SNRPE,STRBP,CD14,RPSA,SOX2,RPS10,CCAR2,CGAS,LYAR,ILVBL,CCT7,NOP9,SURF6,SYNCRIP,ALYREF,KRR1,HP1BP3,CSTA,ECD,SNRNP70,RPS2,ENY2,MOV10,DDX50,RBM17,SPATS2L,NGDN,HNRNPA0,DGCR8,STAU1,NOP53,RPL4,BRIX1,SIRT7,CCDC86,ZNF326,LARP4B,RPL26L1,RPLP0,ZNF574,LUC7L3,RPL35,RPL7L1,RPL19,ESR2,ZNF189,PRKRA,CALML5,CCT2,FYTTD1,FTSJ3,ZCRB1,CHTOP,DNAJC10,EXOSC1,IGF2BP1,NSA2,H1-1,RPF2,HNRNPAB,NOP16,TM9SF4,ZNF668,ZSCAN25 |
| 1.108e-02 | -4.50 | negative regulation of nitric oxide metabolic process | biological process | GO:1904406 | 17 | 10 | 18204 | 5365 |
MIR132,ACP5,IL10,ROCK2,ATP2B4,TSPO,RGN,DYNLL1,MIR212,CAV1 |
| 1.108e-02 | -4.50 | regulation of proton transport | biological process | GO:0010155 | 17 | 10 | 18204 | 5365 |
ACTN4,CHP1,SPHK2,TMSB4X,IL13,PPIF,PHB2,COX17,TESC,NDUFA4 |
| 1.108e-02 | -4.50 | tail-anchored membrane protein insertion into ER membrane | biological process | GO:0071816 | 17 | 10 | 18204 | 5365 |
EMC9,EMC2,SGTA,EMC8,EMC4,CAMLG,EMC1,EMC6,UBL4A,EMC10 |
| 1.108e-02 | -4.50 | regulation of dendritic cell cytokine production | biological process | GO:0002730 | 17 | 10 | 18204 | 5365 |
TLR4,KIT,DDX1,TLR3,BST2,MAVS,TICAM1,RIGI,CLEC7A,TLR9 |
| 1.108e-02 | -4.50 | negative regulation of nitric oxide biosynthetic process | biological process | GO:0045019 | 17 | 10 | 18204 | 5365 |
ROCK2,IL10,MIR132,ACP5,RGN,CAV1,MIR212,DYNLL1,ATP2B4,TSPO |
| 1.108e-02 | -4.50 | cellular response to oxygen radical | biological process | GO:0071450 | 17 | 10 | 18204 | 5365 |
GLRX2,SOD3,SOD2,MT3,SOD1,CCS,PRDX2,PRDX1,NQO1,CYGB |
| 1.108e-02 | -4.50 | cellular response to superoxide | biological process | GO:0071451 | 17 | 10 | 18204 | 5365 |
CYGB,NQO1,PRDX1,PRDX2,CCS,SOD1,MT3,SOD2,SOD3,GLRX2 |
| 1.108e-02 | -4.50 | ribosomal small subunit assembly | biological process | GO:0000028 | 17 | 10 | 18204 | 5365 |
RPSA,RPS5,MRPS7,XRCC5,RPS14,RPS28,RRP7A,PWP2,RPS27L,RPS15 |
| 1.109e-02 | -4.50 | peroxiredoxin activity | molecular function | GO:0051920 | 8 | 6 | 18094 | 5411 |
PRDX1,PRDX4,PRDX2,SELENOF,PRDX6,PRDX3 |
| 1.109e-02 | -4.50 | C-X-C chemokine receptor activity | molecular function | GO:0016494 | 8 | 6 | 18094 | 5411 |
ACKR3,CXCR1,CXCR3,CXCR4,CXCR6,GPR35 |
| 1.109e-02 | -4.50 | small ribosomal subunit rRNA binding | molecular function | GO:0070181 | 8 | 6 | 18094 | 5411 |
MRPS18C,CIRBP,UTP23,MRPS18A,RPS3,RPS13 |
| 1.110e-02 | -4.50 | regulation of cardiac muscle tissue growth | biological process | GO:0055021 | 67 | 29 | 18204 | 5365 |
SAV1,G6PD,CDK1,MIR222,PI16,RGS2,MIR25,FGFR1,MIR208A,RUNX1,MIR548C,PPARA,TOMM70,HEY2,NOG,MIR590,BMPR1A,MIR204,PARP2,RBPJ,IGF1,FOXP1,MIR873,MEF2C,CAV3,VGLL4,WNT2,GSK3A,MIR1-1 |
| 1.110e-02 | -4.50 | translational initiation | biological process | GO:0006413 | 67 | 29 | 18204 | 5365 |
COPS5,NCBP2,EIF2B3,PAIP1,EIF2B2,LTO1,RPS3,ABCE1,EIF2S1,EIF4E,RPS5,EIF4H,EIF3G,EIF4E3,EIF3E,RPS17,EIF1AX,EIF3D,EIF5B,EIF1AD,EIF3K,EIF2B5,EIF4B,EIF2S2,EIF2D,EIF4E2,EIF3J,EIF1B,EIF4A2 |
| 1.112e-02 | -4.50 | MAOB (monoamine oxidase B) | protein interactions | 4129 | 36 | 17 | 19454 | 5460 |
UPK1A,TSPAN3,SYP,CD226,TM4SF18,PPTC7,NFYB,DUOXA2,TRIM54,TACR1,SYNGR1,LPAR2,SLC35G2,COX20,GPR173,S1PR4,TSPAN15 |
| 1.112e-02 | -4.50 | QTRT1 (queuine tRNA-ribosyltransferase catalytic subunit 1) | protein interactions | 81890 | 36 | 17 | 19454 | 5460 |
HPCAL1,QTRT2,GTPBP1,RPA2,FAS,HSPA8,PRSS8,TAS1R2,NOG,THUMPD1,HSPD1,ACSL4,RPA3,RHOU,CDC42EP4,POLE4,ZBTB16 |
| 1.112e-02 | -4.50 | ELAVL4 (ELAV like RNA binding protein 4) | protein interactions | 1996 | 36 | 17 | 19454 | 5460 |
ZC3H11A,EWSR1,SYNCRIP,FAU,RNF41,RPL19,STAU1,CSNK2A1,E4F1,MYC,CSK,ELAVL2,RPL26L1,IGF2BP1,SART3,FBXW11,PPT1 |
| 1.112e-02 | -4.50 | POLG2 (DNA polymerase gamma 2, accessory subunit) | protein interactions | 11232 | 36 | 17 | 19454 | 5460 |
WRAP53,ADNP,RIT1,LIAS,RAF1,MARCHF5,SEC22C,STXBP1,KRAS,GMDS,LYG2,CORO6,LORICRIN,RPS3,IFIT2,HOMER3,PREP |
| 1.112e-02 | -4.50 | TMEM164 (transmembrane protein 164) | protein interactions | 84187 | 36 | 17 | 19454 | 5460 |
GPR17,MOV10,LRRC8B,UPK1A,P2RY12,SYP,BSCL2,HAPSTR1,TACR1,TSPAN15,MME,RIGI,OPRL1,APLNR,EIF2B2,LPAR1,SLC15A1 |
| 1.112e-02 | -4.50 | FBXW2 (F-box and WD repeat domain containing 2) | protein interactions | 26190 | 36 | 17 | 19454 | 5460 |
FBXO42,DENND2D,FBXO7,CTNNB1,MSX2,BTG2,HSP90AA1,BTG1,CLVS2,EP300,MTDH,TRIM54,TTC9C,FBXW7,UBE2L3,SKP1,RIGI |
| 1.112e-02 | -4.50 | ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase) | protein interactions | 85365 | 36 | 17 | 19454 | 5460 |
VPS28,TECR,SRI,PLSCR3,KRAS,LDHA,TSG101,CD79B,ANXA7,RIT1,HSP90AA1,LAMTOR1,ATP1A3,RPA2,HMOX2,CNPY3,FAM20C |
| 1.112e-02 | -4.50 | ITGB8 (integrin subunit beta 8) | protein interactions | 3696 | 36 | 17 | 19454 | 5460 |
RIGI,DYRK1A,VIRMA,PARL,ITGAV,NME4,RAP1B,RPL23,TYROBP,TIMM29,EDC3,RHEB,CDC42,DDX39A,B3GNT2,MICB,GINM1 |
| 1.112e-02 | -4.50 | THBD (thrombomodulin) | protein interactions | 7056 | 36 | 17 | 19454 | 5460 |
F2,CUL3,CIDEB,FCER1G,LMNA,TMEM14B,SERPINA5,PDZK1IP1,APOC2,HRAS,TMX2,APOC4,SLC19A3,PTEN,CYBC1,PSENEN,AIG1 |
| 1.112e-02 | -4.50 | NADSYN1 (NAD synthetase 1) | protein interactions | 55191 | 36 | 17 | 19454 | 5460 |
FRS3,HGS,TP53,TOP3B,CSGALNACT2,EMC6,NTAQ1,AIPL1,HNRNPL,TTC9C,RIGI,TFG,AIP,STUB1,FKBPL,THOC2,EMC2 |
| 1.112e-02 | -4.50 | SPDEF (SAM pointed domain containing ETS transcription factor) | protein interactions | 25803 | 36 | 17 | 19454 | 5460 |
CSK,KLHL9,SNX20,COX5A,STX16,AR,TTC23,STK11,MACIR,NKX3-1,PCGF2,PSMA1,UNC119B,SRPK2,ESR2,ENKD1,IMMP2L |
| 1.112e-02 | -4.50 | SCN5A (sodium voltage-gated channel alpha subunit 5) | protein interactions | 6331 | 36 | 17 | 19454 | 5460 |
WWP2,DLG3,ZMYND19,TOP3B,FGF13,CAV3,EMC9,CRYAB,SNTA1,CBL,DLG1,DLG4,ALB,FGF12,LITAF,RGS2,PTP4A3 |
| 1.112e-02 | -4.50 | TMEFF1 (transmembrane protein with EGF like and two follistatin like domains 1) | protein interactions | 8577 | 36 | 17 | 19454 | 5460 |
KCNJ8,EXOC1,BCS1L,DDX39A,ATP1A3,CCR1,THNSL1,ATP2C1,PTEN,HADHA,SLC39A10,FLCN,MLH3,CAMKV,GOLGA7,DYRK1A,CLDND1 |
| 1.113e-02 | -4.50 | cytokine binding | molecular function | GO:0019955 | 146 | 57 | 18094 | 5411 |
CD4,HYAL2,TGFBR2,CCR7,FZD4,TWSG1,CCR3,TGFB3,ACVR1,IL17F,SOSTDC1,NRP1,IL20RB,IL2RG,GREM1,CXCR3,CXCR6,COPS5,CCR1,HAX1,ACKR3,HMGB1,TNFRSF14,BMPR2,KIT,SOST,IL12A,CER1,IL2RB,CCR2,IFNAR1,CHRDL1,CCR5,CX3CR1,CCR6,IL12B,CXCR4,CNTFR,PLP2,IL6ST,TCAP,BMPR1A,BMPR1B,IFNGR1,LEPR,GHR,IL18BP,NOG,TRAF2,IL2RA,CXCR1,CCR4,IL1R2,TNFRSF1B,GREM2,CD36,ITGAV |
| 1.113e-02 | -4.50 | C-C chemokine binding | molecular function | GO:0019957 | 24 | 13 | 18094 | 5411 |
CCR7,CXCR4,CCR6,CXCR6,CCR4,CX3CR1,CXCR1,CXCR3,CCR5,CCR2,ACKR3,CCR3,CCR1 |
| 1.113e-02 | -4.50 | histone acetyltransferase binding | molecular function | GO:0035035 | 24 | 13 | 18094 | 5411 |
STAT1,TAF7,EGR1,TRIM68,FOXP3,ECD,MTF1,MEF2A,PAX6,EID1,PCNA,TRIP4,SP1 |
| 1.116e-02 | -4.50 | ZNF689 (zinc finger protein 689) | protein interactions | 115509 | 73 | 30 | 19454 | 5460 |
CUL3,NOL12,ZBTB38,ZCCHC9,KRR1,MRPS9,RPS3,ZNF593,CBX5,RPF1,RPL7,RPS16,H2AX,NOTCH2,RPL26L1,ZNF574,APOBEC3C,LLPH,CBX3,YAF2,FGF3,RPL31,RPL17,SRSF12,RPS13,SRSF4,CTNNBL1,HNRNPF,TRIM26,DGCR8 |
| 1.116e-02 | -4.50 | CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit) | protein interactions | 55584 | 73 | 30 | 19454 | 5460 |
DIPK2A,SLC30A7,SNX14,DROSHA,NUS1,BTN2A2,DHRS7,POLR3GL,SLC30A5,ANKRD10,DDRGK1,YKT6,RER1,DNAJC30,TMUB1,HS2ST1,TMX2,SPECC1L,FAM76B,TMEM268,MAVS,EPHX1,KLC2,NUFIP2,TMEM39A,MACO1,NETO2,FUT8,ST7,TIMM29 |
| 1.117e-02 | -4.49 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_I | 30 | 15 | 16828 | 4835 |
TP53,MET,KIT,GNA11,CTNNB1,FBXW7,PPP2R1A,IDH2,AKT1,PIK3CA,FGFR1,PTEN,KRAS,IDH1,GNAQ |
| 1.117e-02 | -4.49 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_I | 30 | 15 | 16828 | 4835 |
KIT,MET,GNA11,CTNNB1,AKT1,PPP2R1A,FBXW7,IDH2,FGFR1,PIK3CA,PTEN,HRAS,KRAS,IDH1,GNAQ |
| 1.117e-02 | -4.49 | PACC1 (proton activated chloride channel 1) | protein interactions | 55248 | 118 | 45 | 19454 | 5460 |
ATP2C1,TSPAN5,STX7,GNB4,UFL1,WDR3,GLRA2,CTXN3,COMMD3,SEC22A,PLP2,CHRNB2,ARMCX3,EIF2B3,PPP2R5E,RAB9B,VAMP3,TNPO3,RANBP6,TMEM38B,ATP1A3,TMEM147,RINT1,SACM1L,PDE2A,CSE1L,USP30,TNPO2,MTCH2,ARFGAP1,DCUN1D5,VAC14,BZW2,GPD2,PWP2,GNPAT,NRSN1,RAP1B,NOP9,EIF2B5,EIF2B2,MZT2B,DDRGK1,DEGS1,CDK5RAP3 |
| 1.117e-02 | -4.49 | CSNK1G2 (casein kinase 1 gamma 2) | protein interactions | 1455 | 118 | 45 | 19454 | 5460 |
CACYBP,GNB1,APEX1,CYP4F12,HSP90AB1,RHOJ,YES1,PRNP,CSNK2B,WDCP,STUB1,SMAD3,OAT,HSP90AA1,EPHA2,SLC20A1,LAMTOR1,SKIC8,DCAF16,NCK1,CSNK2A1,GINS3,PTGES3,FABP4,AHCYL1,FTL,G3BP1,KRAS,CERS2,ACVR1B,APPBP2,JAK1,HADHA,TMEM185A,DDR1,ATP2B4,LRP10,ZRANB2,CSNK1G3,GINS4,FGFR1,FAXC,TMEM231,TOP3B,WDR77 |
| 1.117e-02 | -4.49 | DDR1 (discoidin domain receptor tyrosine kinase 1) | protein interactions | 780 | 118 | 45 | 19454 | 5460 |
IZUMO1,TM4SF1,SNAPIN,TCAF2,TGFBR2,TNFSF8,EFNB1,TSPAN17,CD83,DDR1,SLC25A5,SHC1,MOV10,PIK3R1,MSMO1,CACYBP,HNRNPL,CDCA3,UBE2N,SMAD3,AIP,ZNF326,MYCT1,NUDT3,BEND5,TMEM231,RGS2,CLU,CLDND1,RNF11,PIK3R2,COL3A1,SLC31A1,GPR83,TTR,TSPAN15,EPHA2,HSP90AA1,CHORDC1,PTPN11,VIRMA,ITM2A,SNRNP40,MANSC1,MACROH2A1 |
| 1.117e-02 | -4.49 | MAPRE2 (microtubule associated protein RP/EB family member 2) | protein interactions | 10982 | 118 | 45 | 19454 | 5460 |
FBXO7,MCM4,LMO2,MYC,SFN,MAPRE1,SPOP,NIF3L1,LRRC1,CCNF,LMBR1L,TRAF1,APEX1,SNRNP27,RFXANK,POLR1D,DDIT4L,PAFAH1B1,TRIM36,LMNA,RPA2,FGFR1,HSPA8,P4HA2,RPA3,BAP1,LGI1,DGCR8,GPM6A,UBXN6,CAMSAP2,PSMB1,EEF1AKMT3,EGLN3,SLAIN2,PRNP,MAPRE2,TUBA1A,CDK4,CASK,BAG2,MCM6,H3C1,PSMA5,HUWE1 |
| 1.122e-02 | -4.49 | TUBB8 (tubulin beta 8 class VIII) | protein interactions | 347688 | 376 | 126 | 19454 | 5460 |
CTDSP1,RPA2,HECTD1,CHRNB2,HEXIM1,CCL18,XCL1,WDR5B,KLRD1,HCST,GPIHBP1,IRF3,WNT7A,HCFC2,PHYHIP,RPA3,MME,RNF113A,CST11,CMA1,SPOP,ATP1B3,CDC73,CDC16,TAF5L,PRKCE,ARMC6,TUBA1B,CCNF,AMIGO1,ADAMTS1,KLRC2,RARRES2,TFCP2,TP53,CHRM3,UBL4A,CER1,CLEC2B,MAP2K3,MGARP,CTDSP2,TKTL1,MEPCE,LTA,TFPT,MSMB,ATP1B1,COPS5,COMMD5,EEF1AKMT3,AIFM1,ELSPBP1,NAA30,ARL4D,BRINP2,FA2H,TOR1AIP2,FAM234A,TSHR,NPTN,RCCD1,THBS3,DNAL4,DCAF4,BRCA1,CCT2,BLVRA,RIT1,KLK5,ICAM1,COP1,PRMT6,NXPH3,TUBB,B4GALT3,LYZL6,GNB1,APLNR,PHF12,GTF2F1,FAM43A,CHMP4C,AQP3,PRKAG1,TUBB4B,STK16,NCR3,GNAZ,CRELD1,DTWD2,ETFB,B3GNT2,SOX2,DCP2,ARL5B,G3BP1,SIAE,PAEP,AHCYL1,HINT2,SLC2A8,TNFSF13,LY6G5C,POU5F1,CDH13,PFDN5,FAM174A,ICAM2,PRKX,ACTL6B,P2RY10,HSPB8,LRRTM1,XPO1,CCAR2,GFOD1,CCT7,OPRL1,RAB33A,ELK1,TRMT61A,CIB3,RAMP3,SERPINC1,MAGED2 |
| 1.123e-02 | -4.49 | CYT_DCMP_DEAMINASES_1 | prosite domains | PS00903 | 13 | 8 | 12186 | 3388 |
APOBEC3G,DCTD,APOBEC3B,APOBEC3A,APOBEC3H,APOBEC3C,APOBEC3F,APOBEC3D |
| 1.123e-02 | -4.49 | NUDIX_BOX | prosite domains | PS00893 | 13 | 8 | 12186 | 3388 |
NUDT4,NUDT12,NUDT2,NUDT5,NUDT1,NUDT3,DCP2,NUDT18 |
| 1.124e-02 | -4.49 | H1-5 (H1.5 linker histone, cluster member) | protein interactions | 3009 | 412 | 137 | 19454 | 5460 |
BICD2,SPOP,CSGALNACT1,ELAVL2,ANAPC4,CCNB1,PPP1CC,RPL26,RPS17,H2BC9,B3GALNT1,HPF1,NMI,RPS3,RPS20,RBMX2,HSP90B1,DRD3,CDK1,VPS4B,LMNA,PRKCA,RPL26L1,RPLP0,RPS14,ATG16L1,CCNA2,KDELR2,CDC42,FBXW7,RPL4,HMGB1,RPS15,UTP23,TOMM20,HELLS,RNF113A,PRKCB,MPHOSPH10,H2AC4,AGPAT1,MAP4,RPL10A,RPS2,CMSS1,HDAC6,RPS16,SURF6,DKC1,KRR1,EHBP1,EFCAB7,MYBL2,GPX7,NUPR1,EEF1A1,MAP1LC3B,IMP4,H3C1,RPS13,RPL23A,RPL3,PSMD14,H1-10,FTSJ3,ZCRB1,CYP3A43,BLOC1S5,ZMPSTE24,H1-1,NSA2,SERPINH1,NLRP3,RPS5,PIWIL4,TM9SF4,MYC,BTF3,CALY,USP16,RPL10,IREB2,CBX5,RAN,PARP2,CMTR1,RPS9,FOXP3,RPL37A,MFAP1,USP6NL,SSBP2,CDKN1A,STAU1,ABCC5,RPS28,HIRA,SF3B1,ADGB,HSPA8,AGR2,CDKN1B,POU5F1,HAX1,HNRNPD,PTDSS1,HMGA1,RPS10,TCF21,SRSF1,RBM5,FOLR1,GATD3,RPLP2,HP1BP3,CHMP4C,GLE1,TPPP,EZH2,AP2S1,RPL18,SERPINA5,CCR1,B3GNT2,MSX2,ZNF397,H1-3,TRIM37,SATB1,H1-6,TNF,RAD21,IRAK4,POLDIP3,NEK9,RPL31,CDK5 |
| 1.124e-02 | -4.49 | regulation of osteoblast differentiation | biological process | GO:0045667 | 157 | 60 | 18204 | 5365 |
MIR30B,MIR21,CTNNBIP1,MSX2,PPARG,SNAI2,SOX9,ACVR1,SUFU,MIR106A,MIR20A,MIR320A,MIR100,MIR17,MIR214,ZHX3,MIR208A,CITED1,TWIST2,MEF2C,VEGFA,MIR210,BMPR2,ILK,WNT10B,BMPR1A,FGF23,BMPR1B,MIR200C,NPPC,SMAD1,VEGFC,GREM1,MIR140,HAND2,CDK6,ATF4,NOG,SMAD5,MIR98,IL6ST,FAM20C,PPP3CA,MIR205,MIR9-1,DDX5,IL6,SFRP1,TNFAIP6,CTNNB1,FERMT2,LRP3,ATRAID,MIR675,MIR24-1,SMAD3,TNF,RORB,IGF1,TWSG1 |
| 1.124e-02 | -4.49 | protein sequestering activity | molecular function | GO:0140311 | 29 | 15 | 18094 | 5411 |
SFN,IMPACT,CTNND1,YWHAZ,INSIG2,CAV1,USP38,NFKBIA,SESN2,SDCBP,SEC14L1,CDKN1A,TMSB4X,YWHAG,SQSTM1 |
| 1.125e-02 | -4.49 | TNF signaling pathway | KEGG pathways | ko04668 | 108 | 49 | 7161 | 2463 |
IL1B,PIK3CA,CCL2,TNF,MAP2K6,TAB2,PIK3R3,CREB3,IL15,JUNB,CXCL3,JUN,AKT2,VEGFC,MAPK10,CREB3L4,BIRC2,TRAF2,IKBKB,MMP9,TRAF1,MAP2K3,PIK3R2,AKT1,SOCS3,PIK3R1,MMP14,IL6,TAB1,TNFRSF1B,AKT3,NFKB1,TNFAIP3,FAS,CCL20,CCL5,MAP2K1,ICAM1,ATF4,MAP3K14,NFKBIA,LTA,RPS6KA4,CXCL1,CXCL10,FOS,CX3CL1,CSF2,CREB1 |
| 1.125e-02 | -4.49 | TNF signaling pathway | KEGG pathways | hsa04668 | 108 | 49 | 7161 | 2463 |
PIK3R3,TAB2,MAP2K6,TNF,PIK3CA,CCL2,IL1B,JUN,VEGFC,AKT2,CXCL3,JUNB,IL15,CREB3,MAP2K3,TRAF1,MMP9,IKBKB,MAPK10,CREB3L4,BIRC2,TRAF2,MMP14,PIK3R1,SOCS3,AKT1,PIK3R2,TNFRSF1B,TAB1,IL6,MAP2K1,CCL5,FAS,CCL20,NFKB1,TNFAIP3,AKT3,RPS6KA4,LTA,NFKBIA,MAP3K14,ATF4,ICAM1,CREB1,CSF2,FOS,CX3CL1,CXCL10,CXCL1 |
| 1.126e-02 | -4.49 | TMBIM6 (transmembrane BAX inhibitor motif containing 6) | protein interactions | 7009 | 115 | 44 | 19454 | 5460 |
MARCHF4,FZR1,CD99L2,DUSP3,IER3,TREML1,HSD11B1,SLC1A1,SYNGR1,CDC7,EDNRA,PI16,FGFBP2,FERD3L,CLDN22,BCL2L1,OSBPL8,GZMK,MFSD14B,SCN3B,OPRM1,ADIPOR2,ATG9A,TMBIM6,SLC41A3,PIANP,BFAR,ST8SIA4,DESI1,CERS2,SIT1,SLC7A1,RNF5,TMUB1,TMX2,ERP29,VIPR1,KCNC1,MANBAL,GPR35,TMEM31,ENPP4,VAC14,ESAM |
| 1.127e-02 | -4.49 | response to temperature stimulus | biological process | GO:0009266 | 160 | 61 | 18204 | 5365 |
EIF2B5,DNAJC3,SOD1,SLC25A27,SLC52A3,LIPA,BAG3,ERO1A,SCN2B,CIRBP,ADRB3,HTRA2,EIF2B2,SUMO1,HSP90AB1,EIF2S1,CDKN1A,FGF1,DRGX,DNAJB4,DISC1,HSPB6,CXCL10,ADRB2,RNF34,CXCR4,HSP90AA1,ADRB1,HDAC6,LXN,MICB,HIKESHI,HSBP1,HSPA8,GLRX2,HTR2A,AKT1,CXCL12,HSPD1,PLAC8,ADORA1,STUB1,COMT,ANO3,GCLC,FGF16,HSPB1,CRYAB,HSPB2,SLU7,EIF2B3,TP53INP1,TCIM,IL1A,CLPB,UCP2,RBBP7,IGF1,NFKBIA,NR2F6,CDH8 |
| 1.128e-02 | -4.48 | rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | rosette-forming_glioneuronal_tumour | 15 | 9 | 16828 | 4835 |
GNAQ,FGFR1,TERT,PIK3CA,IDH1,AKT1,IDH2,MET,KRAS |
| 1.128e-02 | -4.48 | skin-lower_leg-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-lower_leg-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
AKT1,IDH1,JAK2,TP53,CTNNB1,KRAS,KIT,PTEN,PIK3CA |
| 1.128e-02 | -4.48 | skin-shoulder-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-shoulder-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
AKT1,IDH1,JAK2,CTNNB1,KRAS,KIT,TP53,PTEN,PIK3CA |
| 1.128e-02 | -4.48 | meninges-meningioma-fibroblastic | COSMIC cancer mutations | meninges-meningioma-fibroblastic | 15 | 9 | 16828 | 4835 |
AKT1,CDKN2C,NF2,HRAS,KRAS,PTEN,SMAD4,TERT,PIK3CA |
| 1.128e-02 | -4.48 | skin-adnexal_tumour-adenoid_cystic_carcinoma | COSMIC cancer mutations | skin-adnexal_tumour-adenoid_cystic_carcinoma | 15 | 9 | 16828 | 4835 |
PTEN,PIK3CA,AKT1,IDH1,JAK2,TP53,KRAS,CTNNB1,KIT |
| 1.128e-02 | -4.48 | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour | 15 | 9 | 16828 | 4835 |
MET,KRAS,AKT1,IDH1,IDH2,GNAQ,FGFR1,TERT,PIK3CA |
| 1.128e-02 | -4.48 | skin-axilla-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-axilla-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
PIK3CA,PTEN,CTNNB1,KRAS,KIT,TP53,AKT1,IDH1,JAK2 |
| 1.128e-02 | -4.48 | pituitary-adenoma | COSMIC cancer mutations | pituitary-adenoma | 15 | 9 | 16828 | 4835 |
CTNNB1,TP53,KLF4,AKT1,CDKN2C,IDH1,JAK2,PIK3CA,TERT |
| 1.128e-02 | -4.48 | dysgerminoma | COSMIC cancer mutations | dysgerminoma | 15 | 9 | 16828 | 4835 |
SMAD4,DICER1,IDH1,PPP2R1A,IDH2,KIT,HRAS,KRAS,BRCA1 |
| 1.128e-02 | -4.48 | skin-groin-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-groin-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
JAK2,IDH1,AKT1,KIT,KRAS,CTNNB1,TP53,PTEN,PIK3CA |
| 1.128e-02 | -4.48 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-epithelioid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-epithelioid | 15 | 9 | 16828 | 4835 |
PTEN,PIK3CA,FBXW7,TP53,KRAS,CTNNB1,KIT,HRAS,RB1 |
| 1.128e-02 | -4.48 | skin-ear-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-ear-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
TP53,KIT,CTNNB1,KRAS,JAK2,AKT1,IDH1,PIK3CA,PTEN |
| 1.128e-02 | -4.48 | skin-vulva-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-vulva-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
PIK3CA,PTEN,CTNNB1,KRAS,KIT,TP53,AKT1,IDH1,JAK2 |
| 1.128e-02 | -4.48 | skin-hand-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-hand-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
PIK3CA,PTEN,KIT,CTNNB1,KRAS,TP53,JAK2,IDH1,AKT1 |
| 1.128e-02 | -4.48 | ovary-germ_cell_tumour-dysgerminoma | COSMIC cancer mutations | ovary-germ_cell_tumour-dysgerminoma | 15 | 9 | 16828 | 4835 |
PPP2R1A,IDH2,IDH1,BRCA1,KRAS,KIT,HRAS,DICER1,SMAD4 |
| 1.128e-02 | -4.48 | large_intestine-colon-adenoma-tubular | COSMIC cancer mutations | large_intestine-colon-adenoma-tubular | 15 | 9 | 16828 | 4835 |
SMAD4,PTEN,PIK3CA,STK11,FBXW7,PIK3R1,TP53,CTNNB1,KRAS |
| 1.128e-02 | -4.48 | skin-foot-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-foot-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
PTEN,PIK3CA,AKT1,IDH1,JAK2,TP53,CTNNB1,KRAS,KIT |
| 1.128e-02 | -4.48 | skin-chest-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-chest-adnexal_tumour-malignant_adnexal_tumour | 15 | 9 | 16828 | 4835 |
JAK2,IDH1,AKT1,KIT,CTNNB1,KRAS,TP53,PTEN,PIK3CA |
| 1.130e-02 | -4.48 | ARHGEF5 (Rho guanine nucleotide exchange factor 5) | protein interactions | 7984 | 76 | 31 | 19454 | 5460 |
CRYBB3,TRIM27,TRIM54,MB21D2,ESR2,SURF6,UBXN6,LMO2,CUL3,SFN,YWHAH,YWHAG,CHPF,MECP2,GLOD4,LRATD1,SHC1,YWHAZ,EPHA2,YWHAB,SNRPA,PICK1,CCDC86,FKBP8,FTL,BRIX1,LMNA,VAPB,SEPHS2,TBC1D13,CRKL |
| 1.130e-02 | -4.48 | NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic) | protein interactions | 4682 | 76 | 31 | 19454 | 5460 |
RIT1,UBE2H,RB1CC1,API5,CUL3,NAA50,ZNF507,EGLN3,PPAT,NDN,GNPDA1,YBEY,POLR3B,ADD1,CCNF,PIH1D1,TAF2,AGAP1,ADNP,ANAPC13,EHD1,HEXA,RNF41,DCTPP1,XPNPEP1,FBXW7,KRAS,NUBP2,RCCD1,LTO1,ZYX |
| 1.130e-02 | -4.48 | RAPGEF6 (Rap guanine nucleotide exchange factor 6) | protein interactions | 51735 | 76 | 31 | 19454 | 5460 |
HSPA8,BAG2,RAP2A,RPA3,FTL,KRAS,KDM1A,RAF1,TOP3B,RAP1A,RPA2,WWP1,GSK3A,MRAS,PHF21A,KRT8,HRAS,CCNF,ENO1,CAV1,APEX1,VIRMA,XPO1,YWHAG,YWHAH,MOV10,SFN,NTRK3,YWHAB,YWHAZ,RHOB |
| 1.131e-02 | -4.48 | regulation of translational initiation | biological process | GO:0006446 | 84 | 35 | 18204 | 5365 |
CCL5,TNF,EIF4EBP2,EIF5B,EIF3E,DDX1,YTHDF2,EIF2S1,EIF4H,EIF2B2,NCBP2,PAIP1,HSPB1,NCK1,RPL13A,YTHDF1,IMPACT,EIF4A2,EIF2AK2,SH3BGRL,UHMK1,EIF4E2,PAIP2B,EIF1B,BOLL,BZW2,PAIP2,EIF3K,ATF4,POLR2G,KLHL25,EIF4EBP3,DNAJC3,EIF4B,EIF2B5 |
| 1.131e-02 | -4.48 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_I | 38 | 18 | 16828 | 4835 |
CLCN6,GNAQ,HRAS,KRAS,IDH1,FGFR1,PIK3CA,KIT,GNA11,MET,CTNNB1,NACC2,TP53,PTPN11,AKT1,PPP2R1A,FBXW7,IDH2 |
| 1.131e-02 | -4.48 | tumor necrosis factor-mediated signaling pathway | biological process | GO:0033209 | 56 | 25 | 18204 | 5365 |
FAS,TRAF6,TNFRSF1B,TNFSF18,PYCARD,TIFA,TMSB4X,STAT1,ACTN4,IKBKB,TP53,NFKBIA,TNFRSF14,TNF,JAK2,RRAGA,KRT8,MIR34A,BIRC2,EDA2R,TRAF1,TRAF3IP2,ILK,TXNDC17,TRAF2 |
| 1.135e-02 | -4.48 | cellular response to starvation | biological process | GO:0009267 | 172 | 65 | 18204 | 5365 |
RNF167,PPARA,TFEB,WDR45,ATF4,GABARAP,FOXA3,ATF3,KLF10,HSPA8,MAP1LC3B,MIOS,RALB,COMT,BGLAP,KICS2,SFRP1,GLUL,FLCN,CTSK,IGF1R,LAMP2,SESN3,TP53,HNRNPA1,YWHAG,SLC2A1,RRAGA,UCP2,ALB,CARTPT,PICK1,STK26,BECN1,SP1,IFI16,SLC38A3,YWHAZ,SUV39H1,FAS,EIF2AK2,SESN2,HSPA5,IMPACT,STK24,PPM1D,ATG7,XBP1,GABARAPL2,DAP,SLC38A2,FBXO22,MAP1LC3A,BMPR2,PMAIP1,RNF152,EIF2S1,GABARAPL1,CDKN1A,PCSK9,RRAGB,SAR1B,SH3GLB1,FOS,NFE2L2 |
| 1.135e-02 | -4.48 | MAP7D1 (MAP7 domain containing 1) | protein interactions | 55700 | 152 | 56 | 19454 | 5460 |
LTBR,RPL3,H3C1,SPC24,CCDC47,RAF1,CTDSP2,KIF2A,TUBB4B,PNMA2,RPS10,FZR1,RPS16,EIF2B5,CGAS,SURF6,FIBIN,IFI16,WWP2,YWHAG,YWHAH,SNRNP70,POU5F1,CAMSAP2,MAP4,YWHAB,RPL10A,BAP1,LCA5,P4HA2,KDM1A,FBXW7,STAU1,FTL,SYK,MRPL12,GRM2,RPLP0,TRIM36,PSPC1,CCNF,DKK3,PRKRA,PHF21A,STAT1,FBXO22,APEX1,SNRPB2,SRPK2,RPL19,MYC,SFN,PPP1CC,YWHAZ,RC3H2,MAPRE1 |
| 1.135e-02 | -4.48 | GGA3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3) | protein interactions | 23163 | 112 | 43 | 19454 | 5460 |
AFTPH,ARF6,STX6,ARF1,SMAP2,TSG101,GJA1,SNX17,PTGDS,LAMTOR1,MYO6,TRIM23,NTRK3,ATG9A,MOV10,RAB11A,LITAF,KRAS,TOLLIP,RNF11,RPS27A,STX7,CYTH2,RIGI,CMTR2,LRP10,BACE1,RAB5A,SQSTM1,IGF1R,VPS33A,RAB4A,VPS18,FGFR1,MET,AP1S2,TRAPPC6A,UPRT,TOP3B,BET1,TP53,TMEM59,SYNRG |
| 1.135e-02 | -4.48 | EPOP (elongin BC and polycomb repressive complex 2 associated protein) | protein interactions | 100170841 | 28 | 14 | 19454 | 5460 |
EZH2,ACACA,TOP3B,MOV10,CUL3,DDX39A,ELOC,RBBP7,RBBP4,PHF1,EZH1,CCT8,EED,KLHL15 |
| 1.135e-02 | -4.48 | TP53I11 (tumor protein p53 inducible protein 11) | protein interactions | 9537 | 28 | 14 | 19454 | 5460 |
TP53,RAB11A,YIPF3,SEC62,RPN1,SSR1,HSD17B11,SEC61B,HNRNPL,KRAS,MANSC1,ESR2,RIGI,GNB1 |
| 1.135e-02 | -4.48 | PDXP (pyridoxal phosphatase) | protein interactions | 57026 | 28 | 14 | 19454 | 5460 |
MED23,RDH12,STK11,CENPM,TP53,NFYA,MOV10,ZDHHC16,PRNP,SLC25A32,RNF11,PRELID1,LMBR1L,CCNF |
| 1.135e-02 | -4.48 | C5orf22 (chromosome 5 open reading frame 22) | protein interactions | 55322 | 28 | 14 | 19454 | 5460 |
DRG2,WBP11,OSM,SPON1,DDIT4L,CUL3,CCAR1,HSP90AB1,DUSP10,KRAS,ELOF1,PQBP1,SURF2,FBXO32 |
| 1.135e-02 | -4.48 | KCNC3 (potassium voltage-gated channel subfamily C member 3) | protein interactions | 3748 | 28 | 14 | 19454 | 5460 |
PAX6,NDFIP1,RHBDD3,FAAP100,KCNC1,JAK1,BMPR1A,DDR1,SLC20A1,RIT1,EPHX1,SLC12A2,FGFR1,KDELR1 |
| 1.135e-02 | -4.48 | VSIR (V-set immunoregulatory receptor) | protein interactions | 64115 | 28 | 14 | 19454 | 5460 |
PLPP6,TSPO2,TMEM97,CLRN2,TNF,TMEM229B,CLEC7A,PLSCR1,VAMP3,SMAD3,TMEM100,DOLK,SMCO4,SLC35B4 |
| 1.135e-02 | -4.48 | SGSM2 (small G protein signaling modulator 2) | protein interactions | 9905 | 28 | 14 | 19454 | 5460 |
CA12,RAB2A,TOP3B,RAB3A,RGMA,ILF2,PNO1,MTDH,RAB9A,RAB9B,RAB3B,MPP1,PTN,HNRNPL |
| 1.135e-02 | -4.48 | ARFRP1 (ADP ribosylation factor related protein 1) | protein interactions | 10139 | 28 | 14 | 19454 | 5460 |
SQSTM1,MAVS,CYTH1,CCT8,TMPO,AP1M1,SRPRB,KRAS,GORASP2,JUN,PIH1D1,LEMD3,GOLGA5,SMAD4 |
| 1.135e-02 | -4.48 | DCBLD1 (discoidin, CUB and LCCL domain containing 1) | protein interactions | 285761 | 28 | 14 | 19454 | 5460 |
DDX39A,CDC42,RAB2A,FAM234A,PDIA3,RHOG,RHOB,RAC2,HRAS,TNFSF8,KRAS,RHOH,CLEC12B,RHOJ |
| 1.135e-02 | -4.48 | SLC16A7 (solute carrier family 16 member 7) | protein interactions | 9194 | 28 | 14 | 19454 | 5460 |
RHOG,FXYD6,SNTA1,TIMM23,RHOB,CDC42,CPEB1,VTI1B,RHOH,RHOJ,RAC2,CDIPT,SFXN1,COMT |
| 1.135e-02 | -4.48 | RPS6KC1 (ribosomal protein S6 kinase C1) | protein interactions | 26750 | 28 | 14 | 19454 | 5460 |
HSP90AA1,LAMTOR1,RAB4A,LAMP3,PRDX3,VDR,LAMP2,ATG9A,VPS39,STX7,RIGI,CAV1,RAB5A,RAB9A |
| 1.135e-02 | -4.48 | WDR53 (WD repeat domain 53) | protein interactions | 348793 | 28 | 14 | 19454 | 5460 |
GLRX,PFDN6,BLVRA,TXN,FN3KRP,TCP1,TXNDC12,UQCRC1,PCCB,MCPH1,AIP,AKT1,RPS28,PFDN5 |
| 1.142e-02 | -4.47 | Polymerase switching | REACTOME pathways | R-HSA-69091 | 14 | 9 | 10285 | 3229 |
POLD2,RFC3,POLA2,RFC4,PRIM2,PCNA,RFC2,RFC5,POLD4 |
| 1.142e-02 | -4.47 | Early Phase of HIV Life Cycle | REACTOME pathways | R-HSA-162594 | 14 | 9 | 10285 | 3229 |
XRCC5,CD4,KPNA1,HMGA1,BANF1,FEN1,CXCR4,PPIA,CCR5 |
| 1.142e-02 | -4.47 | Polymerase switching on the C-strand of the telomere | REACTOME pathways | R-HSA-174411 | 14 | 9 | 10285 | 3229 |
POLD2,RFC3,POLA2,RFC4,PRIM2,RFC2,PCNA,POLD4,RFC5 |
| 1.142e-02 | -4.47 | Leading Strand Synthesis | REACTOME pathways | R-HSA-69109 | 14 | 9 | 10285 | 3229 |
POLD4,RFC5,RFC2,PCNA,PRIM2,RFC3,POLA2,RFC4,POLD2 |
| 1.142e-02 | -4.47 | IRF2BP1 (interferon regulatory factor 2 binding protein 1) | protein interactions | 26145 | 79 | 32 | 19454 | 5460 |
KRAS,FARSA,TRIM37,PML,KLF10,BAG2,DCTN3,KLF3,IRF2BPL,PAX9,PDE6D,ARHGAP1,SOX2,RFXANK,SMAD1,STXBP1,CTSB,IRF2BP1,UBE2L3,ESR2,NUP35,IRF2,ELK3,VGLL4,EEF1AKMT3,FOSL2,AGR2,RIT1,MLF1,IRF9,CUL3,TBCE |
| 1.142e-02 | -4.47 | UTP11 (UTP11 small subunit processome component) | protein interactions | 51118 | 79 | 32 | 19454 | 5460 |
TMEM14B,KIAA0408,IKZF5,H2AJ,EHHADH,TP53,SUMO1,TRIM52,DNAJC22,DPM2,PSENEN,KRAS,FBXW7,STAU1,LSM12,MRPL34,SNIP1,S100B,THNSL1,PEA15,RIT1,UQCR11,ANKRD50,CHCHD1,ANAPC15,CEP70,IFI16,MYC,NDC80,SPPL3,FZR1,FGFBP1 |
| 1.142e-02 | -4.47 | WBP2 (WW domain binding protein 2) | protein interactions | 23558 | 79 | 32 | 19454 | 5460 |
FAM168A,UBE3A,RPS27A,GRPEL1,RIGI,HUWE1,RHBDD3,NF2,TOLLIP,TOM1L2,UBA52,ARCN1,MAGEA4,WWP1,KRT8,EEF1B2,RPS3,HOMER3,ENO1,SMAD5,CCT7,MAD2L2,COPE,TUBB,RUNX1,CTNNB1,BAG3,WWP2,MYO6,CGRRF1,LGALS8,UBE2E3 |
| 1.143e-02 | -4.47 | TXNDC17 (thioredoxin domain containing 17) | protein interactions | 84817 | 50 | 22 | 19454 | 5460 |
ACO1,TXNRD1,ATP6V1C1,EXOSC8,LMNA,PIH1D1,SNX33,TXNL1,REXO2,UBE2K,USP3,CFL1,UBE2H,CLIC2,UBE2N,ATP6V1A,TYMS,PRNP,DYNLL1,NUP35,UBA3,USP5 |
| 1.143e-02 | -4.47 | MFGE8 (milk fat globule EGF and factor V/VIII domain containing) | protein interactions | 4240 | 50 | 22 | 19454 | 5460 |
MTDH,ABCE1,HTR1A,CYB5R3,CD1A,ITGAV,CLEC12B,YTHDF1,PRNP,USP14,CCL3,CLEC2B,DDX39A,BTF3,SOX2,MYC,RSPH1,NUPR1,ITGB5,SFTPC,TAFAZZIN,SDF2L1 |
| 1.143e-02 | -4.47 | KHDC4 (KH domain containing 4, pre-mRNA splicing factor) | protein interactions | 22889 | 50 | 22 | 19454 | 5460 |
MOV10,PRPF19,TP53,PRR13,DNAJC5,EXOC3,NECAP1,UBE2M,RBM23,CALML5,EWSR1,SAT1,PSMB1,KCNIP3,STARD7,TRIM29,SNRNP40,ZDHHC17,RIGI,CDC5L,NUP35,APEX1 |
| 1.143e-02 | -4.47 | RRAGB (Ras related GTP binding B) | protein interactions | 10325 | 50 | 22 | 19454 | 5460 |
TMOD1,SPG21,PDHB,CSE1L,TRIM37,IMMP2L,RABGGTB,FLCN,SQSTM1,CKB,LAMTOR1,BLVRA,LGALS8,CDH13,YWHAB,LAMTOR2,GPR17,NUDT1,CCR6,SLC38A9,LAMTOR3,LGALS3 |
| 1.143e-02 | -4.47 | GCLM (glutamate-cysteine ligase modifier subunit) | protein interactions | 2730 | 50 | 22 | 19454 | 5460 |
RPA2,EZH2,RNF7,PRKCA,PIH1D1,RAF1,GCLC,CFTR,IRF7,HSCB,SEMA4C,IMMP2L,RPA3,SDF2L1,UBE2H,SORD,CUL3,EGLN3,WIF1,GNAI2,CCNF,OPTN |
| 1.143e-02 | -4.47 | RAB39B (RAB39B, member RAS oncogene family) | protein interactions | 116442 | 50 | 22 | 19454 | 5460 |
OPRL1,VPS26C,CBL,BPNT2,LAMP3,LAMP2,C9orf72,ZDHHC17,PIP4P1,SLC15A1,KPNA2,GRPR,TNFSF8,RAB33B,NDUFA4,SLC39A9,HEXIM1,CTLA4,EFHD1,TOMM22,CSNK1E,DUSP14 |
| 1.143e-02 | -4.47 | DAAM1 (dishevelled associated activator of morphogenesis 1) | protein interactions | 23002 | 50 | 22 | 19454 | 5460 |
RHOB,HSP90B1,RHOG,GNAZ,B3GALT4,DNAJC5,CFTR,CDC42,DDX39A,ACTB,RHOH,RHOJ,ARMC6,TUBB,HNRNPL,RANBP6,VIRMA,ESR2,DVL2,FBXL14,RAC2,TMEM185A |
| 1.143e-02 | -4.47 | Signalling by NGF | REACTOME pathways | R-HSA-166520 | 477 | 173 | 10285 | 3229 |
RALA,PSMC1,CUL3,FURIN,LAMTOR3,PIK3CA,AKT1,PEA15,PSMD1,PSMB2,PPP2CB,HRAS,HDAC3,IKBKB,BEX3,SHC1,RASGRP3,PSMD4,PHB1,IL3,PSMA1,DUSP6,FGF1,PIK3R2,IL2RG,ELK1,APH1A,SPTAN1,PIP5K1A,PTEN,NFKB1,MET,PAQR3,MOV10,RTN4,PSMD10,TNRC6C,RAF1,FGF22,MAP2K1,KRAS,PSMD12,JAK1,PRKCE,CSF2,SHC3,AKT2,PSMB9,IL2RA,TRAF6,FGF3,GSK3A,MAP3K11,BAD,PSMC4,VAV2,CRKL,AHCYL1,OMG,PSMB1,JAK2,NTRK2,PSMA2,PSMB6,ADCY2,PSMB11,FGFR1,PSMA4,PDE1B,PSME1,ANGPT1,SPTBN1,UBB,FGD2,PPP2R1A,PTPN11,PSMD14,MEF2C,PSENEN,IER3,VWF,IL2RB,CAMK2G,SOS2,FGF16,SMPD2,AKT3,PSMA6,PIP4K2C,KIT,LAMTOR2,GAB1,IL5,DUSP1,SEM1,DUSP3,PSMB4,SPRED1,RPS27A,CD86,PSMC3,TP53,PPP2R5A,MDM2,YWHAB,ICOS,PEBP1,PSMB3,PDE1A,AP2A1,PPP2R5E,FGF23,PSMA5,AATF,TIAM1,FGF10,PIK3AP1,NFKBIA,SRC,DUSP9,FRS3,RIT1,UBA52,WDR83,RALB,RAP1B,FGF7,CDKN1A,PIK3R3,MAPKAPK3,ATF1,RAP1A,AP2M1,MEF2A,ARHGEF39,AP2S1,MYD88,SPRED2,PSMD6,HBEGF,PSME2,SQSTM1,DNAL4,DUSP10,NEFL,ARHGEF6,CDKN1B,PSMB5,PSMA3,ADCY3,PIK3R1,PSMD3,CREB1,PSMB7,DLG4,CD28,CSK,BRAP,PSMC5,IL2,PSMB10,PRDM4,DNM2,PSMD7,CD80,FGF17,NCSTN,PSEN2,RIT2,PPP5C,AGO1,PRKACB,PRKCA |
| 1.143e-02 | -4.47 | LAGE3 (L antigen family member 3) | protein interactions | 8270 | 109 | 42 | 19454 | 5460 |
RAB3B,KRAS,GON7,MT1A,AHCYL1,RIGI,NFYB,RPSA,TOM1L2,PLP2,TUBA1A,PSMB9,CTSA,GINS4,CNDP2,SEPHS2,ILF2,POP7,PNMA1,PDE9A,SLC1A1,MAGED2,TRIM27,EIF4A2,CAND1,PSMD4,VCPKMT,CCT7,USP5,EGLN3,FAM118B,CYTH4,UBB,CUL2,WDR11,ELOC,TRIM23,PLEKHJ1,ATP1A3,UBE2H,OSGEP,AKAP8L |
| 1.143e-02 | -4.47 | KAT14 (lysine acetyltransferase 14) | protein interactions | 57325 | 109 | 42 | 19454 | 5460 |
TADA3,TADA1,TAF9,MYC,TAF5L,CDC16,LMO2,PCBD1,CEP70,KANSL3,TP53INP1,ACTB,TMOD3,TRIM54,MAD2L1,PHF21A,ZMYM2,TRIM27,CDK8,PPARG,KLF3,PSMC3,SUPT7L,KLF12,WDR37,IKZF5,SUPT3H,DDX39A,KDM1A,SGF29,H3C1,DHX16,RERE,CXXC1,POLE4,GADD45A,HCFC2,PSME1,CORO6,DR1,RUVBL2,HSPB2 |
| 1.149e-02 | -4.47 | regulation of nervous system development | biological process | GO:0051960 | 456 | 157 | 18204 | 5365 |
CERS2,CX3CL1,ASPA,FERD3L,KRAS,TNF,LRRTM2,MT3,OXTR,NKX6-2,TRIM32,CTNNB1,WNT2,CX3CR1,SLITRK2,MAP1B,DKK1,AKT1,CXCL12,CDK5,SPP1,IL1B,PPP3CA,WNT7A,MME,BHLHE40,PROX1,STK11,LRRC24,IL1RAP,WASF3,DUSP10,DRD3,TBC1D24,SEMA5A,PRMT5,HDAC6,TRIM46,TPPP,NOG,S100A10,CXCR4,NRP1,KDM1A,DISC1,PTEN,RGMA,ZNF365,LRRC4B,FGF13,RB1,ADNP,L1CAM,LTA,ASIC2,PPP1CC,MAP2K1,NLGN2,FXR2,TNR,CTNNA1,FZD3,TLR2,FLRT3,KIT,MIR222,RHEB,NEFL,GHRL,XRCC5,RND2,IFRD1,DLG1,CTDSP1,LRTM2,LRRN1,F2,CBLN1,RNF10,DICER1,MIR221,EPHA4,FIG4,IFNG,CTSC,TP53,DLX1,NLGN1,BRINP1,PAFAH1B1,TIAM1,LRRTM1,ASPM,MIR142,LRRTM3,ID4,IL6,SLITRK5,HAPLN2,DAG1,LDLR,YWHAH,HELT,MTMR2,PLXNC1,CRABP2,OPRM1,THY1,GPR37L1,VEGFC,IL6ST,CCL11,HEY2,SYNDIG1,MYRF,IL34,MIR181C,BMPR1A,MECP2,SLITRK1,TRIM11,MIR137,PAX6,TPBG,NF2,LHX2,EZH2,EFNA5,BMPR2,YTHDF2,B2M,SEMA7A,VEGFA,PTPRZ1,GPRASP3,ELAPOR2,AMIGO1,NPTN,SMARCD3,BTG2,TNFRSF1B,TSPO,NR2E1,SMURF1,RTN4,PTN,MIR146A,PSEN1,EGR2,CBLN2,UFL1,FLRT2,SYT4,FZD4,ANAPC2,NTRK2,CLSTN3 |
| 1.149e-02 | -4.47 | CCDC59 (coiled-coil domain containing 59) | protein interactions | 29080 | 106 | 41 | 19454 | 5460 |
PAK5,RBM34,ARMCX3,ILF2,RPL26L1,RPS14,RAF1,RPL15,KRAS,NPM3,DGCR8,MRPS18C,MRPS7,RPL31,RNF167,RPL3,RPS24,NOA1,SNRNP70,RHOB,FTSJ3,MRPS26,DEDD,MYC,MRPS35,RPL7A,GPRASP2,EDC3,MRPS21,RPS10,RANBP6,CDC20,ESR2,SYNCRIP,MRPS9,CCNF,POP7,SRSF1,KRR1,PHB1,MOB4 |
| 1.149e-02 | -4.47 | NDE1 (nudE neurodevelopment protein 1) | protein interactions | 54820 | 106 | 41 | 19454 | 5460 |
TTC1,RAB9A,PICK1,STX11,ZNF365,HSCB,BORCS6,PAFAH1B1,ATG16L1,NDE1,SNAP29,TFIP11,DYRK2,DISC1,CDK1,TRIM27,CTTN,TNIK,ZBTB2,ESR2,VIRMA,JUNB,EGLN3,DYNLL1,TPM3,AR,XPO1,INSYN1,YWHAG,FBXO7,YWHAH,NDC80,PRPF19,MOV10,KXD1,MAPRE1,YWHAB,MED4,YWHAZ,CCDC22,TUBG1 |
| 1.151e-02 | -4.46 | CHMP5 (charged multivesicular body protein 5) | protein interactions | 51510 | 82 | 33 | 19454 | 5460 |
APPBP2,EWSR1,RAB5A,RPA3,HNRNPA2B1,VTA1,PSMC1,CHMP2B,PDE2A,TFG,CHMP1B,STAU1,ISG15,STAMBP,ACACA,VPS4B,RPA2,CHMP1A,SNRPD2,TSG101,PSMC5,CHMP2A,HNRNPL,CHMP5,CGAS,YWHAH,BTF3,PSMA4,VPS4A,HNRNPD,PDCD10,BRCA1,PSMD7 |
| 1.151e-02 | -4.46 | POC1B (POC1 centriolar protein B) | protein interactions | 282809 | 82 | 33 | 19454 | 5460 |
CEP97,HSBP1,RPS16,TCP1,TYMS,NELL2,SARM1,AIP,PELO,PFDN4,PFDN2,PFDN6,TUBG1,CCT2,CHTOP,TDP1,PIP4K2C,INSYN1,PCCB,PFDN5,CUL3,PFDN1,FTL,PRDX4,UNC45A,SRSF2,PDIA6,BAG2,AKIP1,TUBA1A,SPRR1B,CCT5,FAM161A |
| 1.151e-02 | -4.46 | MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) | protein interactions | 8491 | 82 | 33 | 19454 | 5460 |
MRPL11,RPSA,VAPB,MRPS34,CRKL,INPPL1,MRPS18B,MRPS11,MRPS33,G3BP1,KRAS,MRPS17,MRPS7,G3BP2,MYC,MRPS35,NOP16,YWHAG,COPS5,TMA16,MRPS16,SHC1,BICD2,MRPS25,YPEL5,MRPS9,TRAF7,SNRPD1,RPL37A,MRPS28,CAV1,SNRPB2,MRPS23 |
| 1.151e-02 | -4.46 | RAPGEF2 (Rap guanine nucleotide exchange factor 2) | protein interactions | 9693 | 82 | 33 | 19454 | 5460 |
KCTD17,SREK1IP1,SQSTM1,PRPSAP1,ATP5MK,SLC25A11,CTTNBP2,SCYL2,STOM,LMNA,SEC62,RAP1A,LAP3,H1-5,DYRK1A,VIRMA,HNRNPL,TNKS,MOB4,TRMT6,YWHAB,UBE2H,YWHAZ,FBXW11,SPP1,ANO3,RACGAP1,CTNNB1,RAP2B,XPO1,YWHAG,YWHAH,COX5A |
| 1.151e-02 | -4.46 | NOTCH2 (notch receptor 2) | protein interactions | 4853 | 409 | 136 | 19454 | 5460 |
CACNG3,RAB3B,PSEN1,RPL17,GARRE1,ZNF787,NTRK2,ADAMTS1,MTA3,ZNF32,CLEC2B,SMAD1,ARF6,DNAJC1,STX6,TMPO,LMAN1,CAV1,ZNF7,ELSPBP1,HSD17B11,RAC2,PSMB1,XXYLT1,RPL24,RPS2,IGFBP4,STYK1,PRSS12,LAMP3,E4F1,GREM2,FBXW7,HSPA5,RHOU,PSEN2,ZKSCAN1,DERL1,RAB9A,EGFL7,ZNF574,DYRK2,UBA52,CDC42,ST7,ZBTB17,CCR2,RHOJ,DYRK1A,VIRMA,CCNF,SMAP2,ZBTB33,SENP5,MSN,MARCHF3,TAF5L,RAB2A,ZNF687,ZSCAN25,DNAJC5,EPHA4,LAMB2,KRAS,ZNF592,TRIM37,RPS27A,RPS4X,FLOT1,ZBTB45,ZYX,TMT1A,RABGGTB,PDIA6,RNASE4,RPN1,ZNF526,RAB4A,RBPJ,RND3,RPS23,CRKL,ZNF263,TOP3B,DNAJC25,ZNF397,EEF2,HNRNPL,NDNF,RHOH,EGLN3,DIRAS3,SP2,RAB35,SIN3A,ZNF664,GJA1,RHOG,RPL23,ATG9A,LAMP2,CFC1,RAB5C,YWHAG,NDUFV2,YWHAH,CNTN1,HSCB,STX7,ZBTB39,TIMP3,TMEM106B,WNT2,ZFP64,RAB5A,CLDN4,BET1,SUPT3H,SEC62,RND2,ZNF362,TAX1BP1,RPL10,ESR2,WNT10B,ZNF189,SEC61B,LAMTOR1,RHOB,SP1,KLK5,NTRK3,RPS26,RAB11A,CUL3,ZNF668 |
| 1.152e-02 | -4.46 | protein export from nucleus | biological process | GO:0006611 | 32 | 16 | 18204 | 5365 |
SMURF1,NXT1,CCHCR1,CSE1L,RAN,XPO5,CALR,CTDSPL2,XPO1,CHP1,SFN,AHCYL1,DESI1,STRADB,EGR2,NUP42 |
| 1.152e-02 | -4.46 | vesicle tethering | biological process | GO:0099022 | 32 | 16 | 18204 | 5365 |
EXOC8,TRAPPC6A,EXOC5,FAM91A1,TRAPPC4,TRAPPC3,TRAPPC1,WDR11,TRAPPC2L,STARD3NL,TRAPPC13,TRAPPC10,EXOC1,TRAPPC6B,EXOC2,EXOC3 |
| 1.152e-02 | -4.46 | negative regulation of cell junction assembly | biological process | GO:1901889 | 32 | 16 | 18204 | 5365 |
TLR2,SRC,DKK1,MIR105-1,IKBKB,MMP14,DUSP22,ROCK2,IL1B,CORO1C,TNF,PTEN,FAM107A,MIR142,ROCK1,CBLN1 |
| 1.153e-02 | -4.46 | MALL (mal, T cell differentiation protein like) | protein interactions | 7851 | 149 | 55 | 19454 | 5460 |
YIPF3,FAM162A,TMEM31,TMEM182,RP9,CTLA4,EWSR1,BSCL2,PPP1R12A,SNIP1,ARGLU1,ATP5PF,LEPROTL1,NOC4L,CSE1L,STX1A,CDK12,TMOD2,FCGR1A,PHB1,CAV1,TMEM248,FNDC9,RABL3,CPSF4,BRI3,CSNK1G3,CAV2,LMNA,MANBAL,RTN4,TMX2,DDX46,NKAPD1,BNIP3L,SIT1,CLEC12B,PHB2,CREB3,OPRM1,EPHA2,PPIG,REEP6,GGT7,SYT2,CLDN9,RETREG3,AMIGO1,GPR89A,UBE2I,VAMP3,RSRC1,ELOVL4,YES1,SYNE4 |
| 1.153e-02 | -4.46 | GABAergic synapse | KEGG pathways | hsa04727 | 88 | 41 | 7161 | 2463 |
GABBR1,GABRG2,GABRA1,PRKACB,GABRB3,GNG13,SRC,GNB3,GPHN,GAD2,PLCL1,SLC6A11,ADCY3,GNB4,SLC38A3,GNAI3,GNAO1,GNGT2,SLC32A1,GNG7,SLC38A2,GABARAPL1,GNG10,GABRB2,GNG12,GNG5,PRKCA,GNG3,GNB1,SLC38A1,GLUL,PRKCB,GABARAP,GNAI2,GABARAPL2,SLC6A1,GNG2,GNG11,ADCY2,GABRA2,TRAK2 |
| 1.153e-02 | -4.46 | GABAergic synapse | KEGG pathways | ko04727 | 88 | 41 | 7161 | 2463 |
GABBR1,GABRG2,GABRA1,PRKACB,GABRB3,GNG13,SRC,GPHN,GNB3,GAD2,PLCL1,SLC6A11,GNB4,ADCY3,SLC38A3,GNAI3,GNAO1,GNGT2,SLC32A1,GNG7,GABARAPL1,SLC38A2,GNG10,GABRB2,GNG12,GNG5,PRKCA,GNG3,GNB1,SLC38A1,GLUL,PRKCB,GABARAP,GNAI2,GABARAPL2,SLC6A1,GNG2,GNG11,GABRA2,ADCY2,TRAK2 |
| 1.154e-02 | -4.46 | human chr5q31.2 | chromosome location | human chr5q31.2 | 41 | 16 | 26134 | 5823 |
MIR874,CDC23,MATR3,CXXC5,ETF1,PSD2,HNRNPA0,FAM53C,CTNNA1,KLHL3,SPOCK1,FAM13B,LRRTM2,MZB1,EGR1,PAIP2 |
| 1.154e-02 | -4.46 | Histone | pfam domains | PF00125 | 40 | 19 | 17795 | 5224 |
H2AC6,H2AC4,H2AC7,H2BC12,MACROH2A1,H2BC17,MACROH2A2,H2BC14,H2BW1,H2AZ1,H2AX,H2AC25,H2BC9,H2BC1,H2AC14,H2AZ2,H2BC11,H2AJ,H2AC1 |
| 1.155e-02 | -4.46 | GADD45A (growth arrest and DNA damage inducible alpha) | protein interactions | 1647 | 103 | 40 | 19454 | 5460 |
EGR1,FTL,IGSF21,HNRNPA0,PTN,EEF1G,PCNA,ERG28,GADD45A,RBPJ,SH3GLB1,PSMC3,CDK1,EEF1A1,PPARA,RPS7,CDKN1A,LMO4,LNX2,TOP3B,TP53,MDM2,LRIF1,NKIRAS2,GADD45G,APEX1,MPP1,SYNE4,ZHX1,MAP2K6,RPS2,H1-1,FAS,UBE2D1,GADD45B,HNRNPA1,ATG7,GAPDH,TLE1,CCNB1 |
| 1.155e-02 | -4.46 | CERS6 (ceramide synthase 6) | protein interactions | 253782 | 103 | 40 | 19454 | 5460 |
STXBP1,ST7,SEC62,CHRM3,SEC22B,DHX38,ATP5PB,MACO1,CRELD1,GPR35,P2RY12,RPN1,RPA2,BSCL2,LPAR2,TSPAN15,ATP5PF,CERS6,LPAR1,SLC7A1,CERS2,CCR6,GPR17,KDSR,SUGP1,UPK1A,P2RY1,SYNGR1,FZD4,SYT2,RETREG3,CHRM4,LMBR1L,S1PR4,OPRL1,CD1A,APLNR,TNFSF18,HNRNPL,ATP5F1B |
| 1.155e-02 | -4.46 | MANSC1 (MANSC domain containing 1) | protein interactions | 54682 | 103 | 40 | 19454 | 5460 |
STX5,SNX17,VAMP3,TRAM2,TOM1L1,SRC,WDR44,OCRL,CDK17,NRSN2,DNAJB9,VTI1B,NDFIP1,SNX3,TAB1,MBLAC2,MYC,MRM2,PIK3R3,SMPD2,SLC39A3,RNF34,DNAJB4,JAK1,RAB9A,BMPR1A,DDR1,LRP10,SACM1L,PIK3R2,ACVR1B,LGR4,DIRAS1,TCAF2,BET1,TAB2,TSPAN3,PIK3CA,SDCBP,FGFR1 |
| 1.156e-02 | -4.46 | pyrimidine deoxyribonucleotides biosynthesis from CTP | BIOCYC pathways | META_PWY-7210 | 9 | 7 | 902 | 319 |
RRM1,DTYMK,TYMS,NME2,NTPCR,DCTD,NME1 |
| 1.156e-02 | -4.46 | MBD3 (methyl-CpG binding domain protein 3) | protein interactions | 53615 | 279 | 96 | 19454 | 5460 |
BAZ1B,DPY30,EIF3D,AGR2,POU5F1,SIN3A,IGBP1,EED,RAF1,TOP3B,SOX2,JUN,SAP30,EZH2,STMN2,MTA2,SMARCB1,RBPJ,FAM136A,RINT1,PICK1,EWSR1,RBBP7,ZBED1,ZBTB16,SSRP1,RAD21,MYC,CUL3,HNRNPC,CUL2,SMARCE1,PSMD1,MCM4,TTC23,CPSF2,ICA1,FAM219A,PFDN6,S100A6,RAN,RBBP4,ACTB,MAD2L1,ACTL6A,LMO3,TCF19,CSNK1A1,DDX5,STAU1,SAP18,SKP1,CENPP,CSNK2A1,KPNA1,BRD3,H2AZ1,MYBL2,GATAD1,BRMS1L,SHPRH,ZBTB2,MTA3,KBTBD4,MAP1LC3B,H2AX,TNNI1,IK,TAB2,TBC1D19,H3C1,KPNA2,CDK2AP2,PHF1,MEPCE,SMARCA5,CEP70,TXNIP,SERTAD3,CCHCR1,CSNK2B,TRIM27,ZNF655,MACROH2A1,TRIM54,VIRMA,POLR1D,SDCBP,HSP90B1,ACACA,BAP1,RNF113A,KDM1A,LDOC1,MBD3,BCL6 |
| 1.157e-02 | -4.46 | CLSPN (claspin) | protein interactions | 63967 | 85 | 34 | 19454 | 5460 |
RPA2,CBX3,ACACA,CSNK1G3,NLE1,RPA3,LTA,NUP50,IGF1R,TRIM21,PCNA,ASF1A,SSRP1,MSH6,GINS3,CUL3,GJB2,MYC,XPO1,BRCA1,FBXW11,RIT1,TNNC2,SRP14,ARL4D,CSNK2B,CDC7,MIF,MPP1,FZR1,JAK2,CDC20,EGLN3,CDK9 |
| 1.157e-02 | -4.46 | ZAP70 (zeta chain of T cell receptor associated protein kinase 70) | protein interactions | 7535 | 85 | 34 | 19454 | 5460 |
ASB3,RNF41,KIT,SIT1,ANAPC11,PELI1,MET,CRKL,PTPN22,DDX39A,TUBA1A,CD38,LCP2,DUSP3,DAPK1,TUBB,RHOH,CD4,CD3G,SLA2,CD79B,TUBA1B,CBL,CD247,TYROBP,RIT1,NDUFB8,SHC1,SHC3,BTF3,IFNAR1,CSK,PIK3R1,USP2 |
| 1.157e-02 | -4.46 | MORC2 (MORC family CW-type zinc finger 2) | protein interactions | 22880 | 85 | 34 | 19454 | 5460 |
LDLR,UBE2I,ZNF330,APEX1,ESR2,VIRMA,FBXO22,DDRGK1,NONO,CSNK2A1,BTF3,CUL2,HNRNPD,DDX23,NUP50,P4HA2,XRCC5,RPA3,MORC2,RIGI,PAX6,OLA1,COIL,STAU1,KRAS,B2M,H3C1,H2AX,MAX,RAF1,ARCN1,CBX3,TUBB4B,RPA2 |
| 1.158e-02 | -4.46 | ERP44 (endoplasmic reticulum protein 44) | protein interactions | 23071 | 174 | 63 | 19454 | 5460 |
ID1,UBFD1,FAM53B,PDCD10,SMCHD1,PEDS1,AGR2,EDEM1,FAM20C,G6PD,EGLN3,PRNP,SNX2,COPS7B,TRAPPC10,USP46,PLD3,ADAMTS1,ACTN4,B3GNT2,IL12B,IMMP2L,SAR1B,ARF4,RPIA,VPS26B,CASTOR2,TRIM21,ERO1A,UBE2H,PNPO,NTRK3,OSGEP,CDC73,POU1F1,YWHAZ,RBBP8,CKB,FAS,CRLF3,GORASP2,ACO2,FERMT2,DAPK1,COPE,SEC61B,CCNF,LMBR1L,UBE2M,IDH2,ISOC1,PAK2,EDEM3,YIPF5,NFYB,SF3A1,PIAS1,RER1,HSCB,POLD2,TMEM106B,PRIM2,CD40 |
| 1.158e-02 | -4.46 | SMCHD1 (structural maintenance of chromosomes flexible hinge domain containing 1) | protein interactions | 23347 | 174 | 63 | 19454 | 5460 |
OPTN,CMTR1,ELK3,ZNF330,PTEN,SGTA,MATR3,LRIF1,APEX1,ESR2,VIRMA,SRPK2,NMI,MYC,AR,USP14,BRCA1,PDCD4,UBE2H,RPA3,PML,SIRT7,DERL1,UFL1,STAU1,SF3A1,LMNA,RPA2,IDH2,SPRED2,EEF1AKMT3,EED,TSG101,FZR1,RPL35A,SUMO2,SPTAN1,PEG10,CDC5L,WIF1,CEP19,IFI16,DDRGK1,BRD3,LHX2,TRIM21,SEPTIN7,H3C1,TOLLIP,UBE2A,MDC1,PAX6,FBP1,RAF1,PTS,ACTN4,SOX2,LGR4,ELF1,CBX3,EZH2,CAMK1,NUPR1 |
| 1.159e-02 | -4.46 | organelle envelope lumen | cellular component | GO:0031970 | 91 | 37 | 19108 | 5553 |
HTRA2,CHCHD4,TIMM13,STAR,RNASET2,TUBB,COX17,ARL2BP,TIMM29,CACYBP,ALPL,COA4,CD2AP,TIMM10,FGR,STOML2,UQCC2,HAX1,AIFM1,NDUFB7,SOD1,CMC4,CHCHD2,PRELID1,FBXL4,TIMM8B,NME4,FKBP10,AK2,TIMM8A,CCAR1,AGK,COX19,PTGES,TIMM23,CLPB,REXO2 |
| 1.159e-02 | -4.46 | LRCH3 (leucine rich repeats and calponin homology domain containing 3) | protein interactions | 84859 | 100 | 39 | 19454 | 5460 |
PIH1D1,PARD6A,CAPZA2,TULP3,CDC42,E2F4,ATG16L1,RNF26,DPM2,FBXW7,DGCR6L,ERLEC1,SEPTIN7,DDX39B,UQCR11,ANKRD50,VCPIP1,MYO6,SMAD4,CRLF3,HDAC6,YWHAG,VAMP5,IFI16,CSK,MYC,VIRMA,ESR2,DYRK1A,SH3BGRL,UBE2V2,PTP4A3,EGLN3,CBX5,MIF,TMOD3,HNRNPL,CORO1C,CCNF |
| 1.159e-02 | -4.46 | TTC27 (tetratricopeptide repeat domain 27) | protein interactions | 55622 | 100 | 39 | 19454 | 5460 |
NCDN,RPA3,VIPR1,RUVBL2,KRAS,KDM1A,TSSC4,CCT5,CFTR,MGARP,GFPT1,CD2AP,FAF2,ACVR1,HDAC11,RPA2,CSNK1A1,LMBR1L,S1PR4,CCNF,PHF21A,TCP1,DAPK1,CCT7,VIRMA,DHX15,PTP4A3,EGLN3,ILVBL,CUL3,MYC,BMPR1B,DDRGK1,UFD1,COPS5,ECD,CCT2,RIT1,KLK5 |
| 1.159e-02 | -4.46 | AFG2B (AFG2 AAA ATPase homolog B) | protein interactions | 79029 | 100 | 39 | 19454 | 5460 |
WDR6,LMBR1L,CINP,CCNF,ANAPC2,SUMO2,PRNP,SSH3,GFOD1,RPL10,FAM174A,CUL3,EMILIN1,SKAP2,DDRGK1,CFAP161,XPO1,FBXW11,SNRNP70,RC3H2,FAS,THTPA,RIT1,RCCD1,BAP1,MAP1B,SQSTM1,RNF113A,EXOSC4,HSPA8,KRAS,HSCB,ATG16L1,SYK,TIMM8A,RPL15,TIMM13,WRAP53,CAPN2 |
| 1.159e-02 | -4.46 | ECI2 (enoyl-CoA delta isomerase 2) | protein interactions | 10455 | 100 | 39 | 19454 | 5460 |
FZR1,ATP5F1B,CGAS,EGLN3,IDE,TNPO3,TRAF1,VIRMA,CD274,EEF2KMT,GATD3,TNNC2,H1-1,UBE2H,MYC,AUH,PMPCA,BAG3,TUFM,KDM1A,HSCB,STAU1,HSPD1,RPA3,GFM1,COX8A,UBE3A,RPA2,PDHA1,METTL14,NDUFS3,ACOT13,MET,MTRES1,MRPL11,NDUFA2,CARTPT,MRPL12,CFTR |
| 1.159e-02 | -4.46 | PLG (plasminogen) | protein interactions | 5340 | 100 | 39 | 19454 | 5460 |
EP300,RAP2A,MMP9,HSPD1,PRDX4,UFL1,CYFIP2,S100A10,SERPINB6,HMGB1,RUVBL1,IGFBP3,FBP1,TP53,CCR1,E2F6,SERPINI1,METTL14,LMBR1L,SERPINC1,SMAD3,F10,ENO1,KLK3,CHGA,PLG,ATP5F1B,ACTB,PRNP,ARHGAP21,DDRGK1,RACGAP1,CDC73,HSP90AA1,SLC6A1,AGPAT1,UBE2H,HSPB1,SMAD4 |
| 1.159e-02 | -4.46 | TSPAN3 (tetraspanin 3) | protein interactions | 10099 | 100 | 39 | 19454 | 5460 |
UGCG,CSNK1G3,SDCBP,FGFR1,CLEC2B,IFNGR1,ADIPOR1,TP53,GABARAP,GOLGA7,EPHA4,PGAP4,ACVR1B,LPAR1,GPM6A,TACR1,EWSR1,BSCL2,RAB13,LRP10,TSPAN15,LRRC8B,CCR6,CLDN11,KDSR,TRIM32,TM9SF4,GPR17,STX6,VAMP7,SRC,OPRL1,TNFSF18,MANSC1,LGALS3,NDFIP1,SNX17,LMBR1L,CD63 |
| 1.161e-02 | -4.46 | SCARA3 (scavenger receptor class A member 3) | protein interactions | 51435 | 88 | 35 | 19454 | 5460 |
RAB11A,SCN3B,RAB5C,MLF1,MOV10,LAMP2,EXOC2,LAMTOR1,DEGS1,SDF2L1,ENO1,NDUFB4,TNPO3,FIBIN,LGALS3,C1QTNF1,HNRNPL,DNAJB9,COCH,CLEC2B,EMILIN3,TMEM106A,SYNGR2,TOP3B,NCR3,LMNA,MAN1A2,MMP9,CLK1,TMEM106B,TMEM87A,STX7,CMTM6,CNOT7,ERLEC1 |
| 1.161e-02 | -4.46 | NOSIP (nitric oxide synthase interacting protein) | protein interactions | 51070 | 88 | 35 | 19454 | 5460 |
PPP2R1A,ATG16L1,RAF1,PIH1D1,RTF2,NUPR1,CBX3,DDX42,LMNA,EP300,HMCES,HSPA8,PML,RPA3,RIGI,PRPS1,STAU1,POLL,KRAS,UBE2D3,G3BP1,HSCB,DDRGK1,XPO1,PTPN11,CUL3,MYC,UBE2H,TNNC2,COP1,SLC25A21,KPNA1,PPP2CB,EGLN3,SNRNP40 |
| 1.162e-02 | -4.45 | CASP7 (caspase 7) | protein interactions | 840 | 97 | 38 | 19454 | 5460 |
AR,FBXW11,STK24,CCT2,NIF3L1,SP1,BAX,EIF2AK2,DFFA,RB1,SPTAN1,STAT1,EIF4H,ROCK1,TP53,CAPN1,MAX,MVD,EEF2,TRAF2,CDC42,CTSA,NFE2L2,RNF7,CRYAB,CTBP1,CNDP2,BIRC5,PSEN2,PLA2G4B,BIRC2,SAT1,SCPEP1,HSPA5,RAD21,PTGES3,MEF2A,PSEN1 |
| 1.162e-02 | -4.45 | E4F1 (E4F transcription factor 1) | protein interactions | 1877 | 97 | 38 | 19454 | 5460 |
RPL17,MRPS7,MRPS18C,RPS27A,RPS13,MRPS33,RPS24,MRPS11,MRPS18B,SF3B1,RPL3,ZNF770,RPL26L1,ZNF574,TP53,NOTCH2,ANP32A,RPL19,SURF6,MRPS23,DKC1,RPF1,RPS16,RB1,GATAD1,MRPS9,NSA2,H1-1,ELAVL4,SMAD9,MRPS25,ZCCHC9,ZSCAN25,RPL26,CSNK2A1,MRPS35,MOV10,IFI16 |
| 1.163e-02 | -4.45 | organic cyclic compound metabolic process | biological process | GO:1901360 | 3526 | 1095 | 18204 | 5365 |
NDUFV2,EPOP,ASCC1,RPL35,CNP,FTSJ1,ZC3H7A,MCM4,CSGALNACT1,NCBP2,SLC25A39,DDX5,LEPR,TRMT13,DDX23,HENMT1,MPG,MAP1S,MAEL,TP53,GNAI3,VCPIP1,RBMX2,PIP4P1,KLF4,USP39,IMP3,RPS15,RARS1,MPP1,POLR1H,ALKBH3,HMOX2,RAD1,SAP18,ZNF473,MGMT,UGT1A1,EMG1,CNOT8,GEMIN7,ZNHIT3,HSPA8,INTS10,ZNF326,PIWIL1,CYB5R1,GPHN,GTF2I,TCEA2,FAR2,DROSHA,PRIM2,HINT1,WDR6,HMCES,KPNA2,ZNF668,LGALS3,CYP27B1,MLF1,RBM3,UFL1,RBM15B,TRMT61A,GMPPB,SC5D,APOBEC3H,PAPSS2,TRA2A,PPWD1,NQO1,SNRNP40,DDX46,SUV39H1,DIO1,TEX12,PHB1,RPA2,PDE12,RUVBL1,EXD2,SHMT1,CYP17A1,HMGA1,CYP11B2,SF3B1,PPT1,GINS4,PCLAF,HINFP,MED11,KDM2A,ATP5MK,GTF2A2,CYP4F12,CYP3A5,STUB1,SSU72,TOP2B,TOPBP1,PLAC8,BCL6,PRPF18,FDFT1,ELOVL1,RB1,IK,CITED1,CYP11B1,SLC22A12,CD2BP2,RSRC1,ZNF365,TYMS,MED4,TOP1,LSM3,SUPT5H,NFYA,FOLR1,DCTD,RBM5,CDK9,FUT8,MFAP1,NHEJ1,SDHB,CASC3,H2AB1,PDHA1,CEBPG,RBM38,SNRPD1,GTF3C3,ALDH1L1,RTRAF,ARMC7,CSNK1E,RCHY1,AGO1,GGH,FZR1,SREK1IP1,SPR,PELP1,HACD2,DDX42,RPS14,MMUT,TSSC4,BARX2,NDUFB7,GTF2F2,PDE7A,OSGEP,SLC48A1,SRSF12,ATP5F1A,YWHAH,NDUFS8,PMM2,SHPRH,BLVRA,SWAP70,RUVBL2,CYP3A43,MOXD1,FASTKD5,THG1L,TRMO,GPBP1L1,AK2,SNRNP48,FAM98A,EPHX1,FXN,LSM10,ATP5PO,DGCR8,NUDT1,PAAF1,HTRA2,MDC1,THAP1,TAF5L,NDUFC2,IL4,GTF2H4,AANAT,SUGP1,TRMT5,ZMAT2,SLC2A3,LSM2,RPRD1B,SMNDC1,LTO1,LIAS,PLD3,RPIA,PDE1A,DPEP1,OSBP,ATP5MG,LRWD1,GTF2B,STAT6,RNF8,UAP1,CCR6,SF3A1,GINS3,THOC3,ZNF345,DDX4,ADRB2,ZNHIT6,SRSF7,SULT1A3,MCM8,HAND2,PRDM4,CHRAC1,RMI1,LDHA,DBR1,RFC2,GLRX2,SPP1,OLA1,RPP25L,DHX9,RPA3,HSD11B1,AMACR,SLC19A3,STPG4,CTU1,NUCKS1,TSN,BUD23,NHP2,PELO,DNPH1,PRPF19,DHX15,NR1I2,CTSB,KDM1A,CDC5L,POLA2,DICER1,IMP4,ZCCHC7,CWC15,TOPORS,RBM23,DLG1,MVD,CNOT6,SF3B5,QTRT2,CYP1A1,LSM8,BANF1,GLRX,HNRNPA0,CSNK2A1,EXOSC4,CPEB1,RPL7,SUB1,TMT1A,RGN,CPSF4,NSA2,SART3,SOX9,PPIG,SUPT4H1,OARD1,THOC1,MAGOHB,CYP39A1,WDR55,ADRM1,WDR12,ATP5PB,TAF10,NMRK1,ELOVL3,RBMS2,APEX1,NDUFS2,ADK,GMPS,UTP25,TRMT11,GIN1,RPL35A,ABCG2,COX11,HSD17B8,CD40LG,UGT2A3,INSIG2,HNRNPA2B1,RBM41,PDE4B,NDUFB10,GTF2H2,WRAP53,MMADHC,NT5C3A,HMGCS1,ALKBH2,CMPK1,GTF3C4,SAMHD1,NDUFB4,NSMCE3,PDE1B,GTF2E1,ALPL,BCL9,RRM1,FGF23,CYP4V2,EIF3E,MTPN,NUDT16,AK5,NIBAN2,DEK,SLC52A3,ELOVL4,CDC40,TRUB1,CRYM,NDUFB8,SSRP1,PIK3R1,RAN,CPSF2,TERB2,CTNNBL1,NDUFS6,RLIG1,MED9,GPAM,TRMT112,EGLN3,MRM2,STAR,CNOT6L,SLC23A2,NPC2,MED23,LHB,SLC2A1,ERH,PARP2,RBM17,TCEA1,UCKL1,SGF29,NOL7,INTS12,EAF2,NME2,FBXW7,FOXA3,POLDIP2,CCAR2,MED22,APOBEC3C,MAK16,CH25H,NOC4L,MED10,MSMO1,HNRNPL,DRD1,PIH1D1,SLC16A10,CACNB4,ATP5F1D,EXTL2,HSD17B3,DHRS11,GCFC2,MRTO4,H2AC25,NPPC,PDE2A,WBP2,KIN,RBM42,POLR2B,UCK1,VPS54,TRMT10B,AKAP8L,RPL7L1,PTHLH,XRCC5,TRMT6,BPGM,CYP21A2,CCNH,GTDC1,APOBEC3A,MRPL12,C1D,PRPF31,CYP1B1,ENTPD4,G6PD,UTP6,ENPP4,NOP58,DDX39B,PADI2,ADAT1,CETN2,LSM5,ACAA2,ACSL4,NKX3-2,POP5,THOC6,CYP27A1,DNTT,RAB23,POLD4,ERLIN2,DDX1,SUCLG2,POLR2C,MCM6,SF3B4,GNPNAT1,SMN1,DUS4L,TENT4A,GPD2,SLX1A,COPS2,ACTL6A,ERRFI1,DLAT,RCL1,FOXP3,BABAM1,EXOSC1,NUDT19,RPL7A,GTF2A1,NCAPG2,MED27,PAX6,REXO2,PAPOLA,ADSS2,MAD2L2,GFPT1,GMDS,URM1,EDNRA,WNT10B,MGME1,MDH1,DHX16,RAMAC,DTD1,CDC73,SRD5A3,RBM34,HDAC3,TKTL1,MTAP,SMG8,VDR,RBBP4,ATP5PD,PRPS1,DIO3,UCP2,WTAP,CNOT2,ENY2,UBE2W,DKC1,CYB5R3,SIRT7,SKIC8,TTR,GRSF1,FUBP3,EXOSC8,RTF2,METTL15,MTERF2,PFKFB2,FKRP,LBR,RPL26,CLP1,ELAVL4,CEBPE,DYRK1B,PAXX,EGLN2,ATP5MC1,SRFBP1,DIO2,RPRD1A,SMU1,DCK,TAF11,PPP5C,E4F1,FTSJ3,PCSK9,NR1H2,IL2,MSH6,TP53I3,CYTL1,HIRA,SNAPC5,HNRNPAB,AR,RPE,TERC,MND1,XBP1,PNPO,RPL27,SLCO2B1,SLCO1B3,COX10,APEX2,ZMAT5,VPS72,UBE2D3,FHIT,TAF7,HSD17B11,CHST10,NOP9,ORC6,ERCC3,IDO1,HUWE1,DCLRE1C,POLR1B,SMG9,TSEN54,EYA3,UGDH,TFPT,ENO2,POLE3,DNAJC2,NONO,HELT,COMT,NDUFAB1,SRSF1,FGFR1,MTHFD2L,CMTR2,ATXN1L,ACSS2,RRP7A,PIWIL4,PYCR1,YTHDF2,UPF3B,AASDHPPT,ATP5F1E,AK3,GNPDA2,LSM6,POLR2L,MNAT1,RAD21,NR4A2,CLN8,CNOT7,FANCG,CHCHD4,EGR1,GAPDH,POLE4,PPARG,LIPA,NSDHL,CYP7A1,NUDT7,CCNA2,GSTO2,DCP2,SDHC,PDE9A,TSPO,BTG2,GNPDA1,FAXDC2,SESN2,DBH,MSX1,RFC5,CINP,RPS3,PPP1R1B,ETF1,RBBP7,STN1,SRSF8,SRSF2,GTPBP1,S100A10,BCCIP,HNRNPH3,PRPF4,DPAGT1,CARS1,BATF,BRIX1,HMBS,MME,DFFA,HMGB1,PIR,EPHA2,INO80C,TRA2B,GUCY1B1,RAG1,H2AX,NFE2L1,OGG1,QRSL1,TFB1M,CGAS,NUDT3,FRA10AC1,RPF2,TSEN34,APOBEC3B,RFC4,ELOVL6,SPHK2,PPAN,PPIH,SLC29A1,ACOT8,HSD17B1,TRIR,PSMD14,RPS28,KTI12,MCMBP,MTHFS,DIS3L,CFTR,RAD23B,LDB1,RPS16,CREB1,IER3,SNCB,TYW5,MARS1,TDP1,SLC25A1,APOBEC3G,SCNM1,TDRD7,ZSWIM7,SLU7,DNAJC30,FITM2,CASK,FMO2,GSTM3,TPH2,FAAP100,HNRNPA1,WWP2,NUDT18,THOC2,NFIL3,HSP90AA1,MED21,USP15,POLR3GL,NDUFA12,PWP2,UBE2A,CYP2F1,GLYAT,APOBEC3D,CYP26A1,SNIP1,CDK1,POLR2D,SSBP1,OAT,DDT,HTR2A,NME4,CD28,CBFB,HSP90AB1,ERLIN1,LDHB,CDKN2D,ACOT6,POLR3H,RPP14,RBBP8,ATP6V1A,MEPCE,RC3H2,HTR1A,FCF1,RBFOX2,SMG5,DCTPP1,WBP11,YBEY,POLR2I,SNRNP70,SNRPG,SNRPA,APOBEC3F,ARB2A,PLPP6,SLC19A2,RNF113A,DTYMK,ZCRB1,IRF9,MPHOSPH6,ZMPSTE24,CYP2D6,NUDT5,RBM22,BUD31,BRCA1,ALKBH5,SMAD2,TAF2,PCNA,SNAPC1,ATP5F1B,TWNK,RPP21,NUDT2,SHOC1,TCEANC2,SNRPD3,POLB,DPY30,SLC6A3,SRPK2,RBM7,GTF2H5,TGFB2,DTWD1,PIWIL2,RP9,RTCB,PDHB,FARSA,AP5S1,PROX1,NFKBIB,PDE8A,SLC5A6,GCLC,NDUFA1,QNG1,NPM3,GSTM2,FMO1,PGAM1,ABHD14B,PRKCB,WDR3,ORC5,PAGR1,IDH1,SNRPE,METTL25B,HNRNPC,SUMO1,SNRPA1,ERG28,NABP1,SMAD1,MACROH2A1,XPO5,COIL,ATP1B1,PTTG1,P4HA2,CDK7,PYM1,ATP1A2,NDUFA2,ATP5PF,CWF19L1,FEN1,TECR,MTF1,MEF2A,PRKRA,ELOF1,PGM1,DHX38,DLST,CPSF1,PGRMC1,NUDT4,GPR37,DTL,MEIOB,MACROD1,TENT2,ZRANB2,RBM27,MED17,ATP5MC3,TCOF1,METTL6,CBLL1,HNRNPK,LEP,IDH2,SQSTM1,POLR2G,SF3B6,MCM3,ATF4,NOVA1,SNRPB,POLR2F,NRDE2,NME1,CSTF2T,PTGES3,PIWIL3,SMARCA5,SRC,PPIL3,SDR42E1,DRAP1,RTL4,SMUG1,SRSF4,CELF6,EXOSC3,EDC3,AKR1C1,SNX17,NFE2L2,HNMT,AKR1C2,PRMT6,PTS,SMARCB1,MECP2,NOB1,IVNS1ABP,AKR7A2,HACD1,UBL5,TFIP11,SNAPC2,RPS24,PGK1,METTL14,RPP25,NBN,MGAT1,KRR1,GTF2IRD1,ALYREF,GSTO1,UTP15,FAH,IRF1,DTWD2,SLC25A32,PQBP1,EIF4A3,TEX19,PNRC1,KMT5B,TAF9,SNRPN,POLD2,HNRNPD,ELOC,TEX264,CMTR1,SARM1,NT5C2,PCBD1,SMAD3,TRMT1L,HSD17B6,RNASEH1,ELP3,PKNOX1,RPS7,NDUFA5,AKR1B1,SNRNP27,TYW3,GFUS,PPAT,MED30,WDR83,GTF2E2,THTPA,TERT,NFKB1,RNASET2,NDUFB5,PABPC1,SUPT3H,UGP2,SLC11A2,FOS,TFCP2,CLPX,NUDT9,HINT2,RPAP2,SNRPD2,CYP2C9,HNRNPF,CBR4,URAD,UTP23,TXNL4A,UMPS,SYCE3,MMAA,ACAT1,TSR3,TPST1,NUDT12,CD38,GSTM4,NDP,GADD45A,GTF2F1,NDUFB6,CRMP1,VIRMA,STOML2,ASMT,THRAP3,SNRPB2,RPS17,RNASEL,POLR3B,RNASE6,SULT1B1,GNMT,LUC7L3,THUMPD1,PPP4C,UCK2,OSGEPL1,UPRT,PNP,TOP3B,DMAP1,TRPC1,HSPD1,LDLR,ENO1,MPHOSPH10,POLR3F,DXO,NDUFS3,IREB2,RMI2,SRSF10,LIG3,MED29,KHDC4,SIN3A,ADCY3,PC,SNAPC3,LYAR,ELOVL7,APTX,ENTPD3,MLH3,DCAKD,WDR82,ELP6,DHRS4,ECD,RBFOX3,METTL2A,ESS2,PCK2,ABCC2,GUK1,CREBL2,TIA1,UBE2B,MFN1,OGDHL,NGDN,SYNCRIP,PRPSAP1,CTSK,BACH1,SHLD1,NPR2,SLC1A1,CRTAP,RPF1,CTNNB1,CYP2R1,TSNAX,RFC3,MAGOH,UQCC3,EP300,DR1,GEMIN8,KARS1,NPC1L1,HSD17B10,POP7,WDR77,CSTF3,DNASE1L1,LSM4,PRMT5,INO80E,SMAD4,ISG20,DRD3,RNASEH2C,UBE2V2,GMNN,CDC7,DPH3,UBE2V1,GON7,NOP53,PYCR2,AKAP17A,PPP1R8,ADCY2,ASF1A,KPNA6,AKR1A1,POLR1D,ACACA,SMCHD1,BAD,DTD2,JAK2,MORF4L1,MED31,DDX39A,INTS6L,VLDLR,TSR2,USP3,ATP5IF1,CDK12,CYP2C8,RRN3,TRIM24,UBE2N,RIOK2,HPF1,POLL,MMACHC |
| 1.163e-02 | -4.45 | BRAT1 (BRCA1 associated ATM activator 1) | protein interactions | 221927 | 91 | 36 | 19454 | 5460 |
CYB5B,RFXANK,HCST,LPAR6,TOP3B,COMTD1,TPT1,RIGI,ENKD1,G3BP1,NPTN,CD80,PML,FXYD6,SLC2A1,PSMD7,BRCA1,P2RY10,AR,GSTM3,MYC,UBXN6,GPR17,NXPH3,OPRM1,CUL3,APLNR,NMI,GNAI2,TAX1BP1,TMEM108,LMBR1L,CD274,OPTN,CHRM4,EEF1AKMT3 |
| 1.163e-02 | -4.45 | TKFC (triokinase and FMN cyclase) | protein interactions | 26007 | 91 | 36 | 19454 | 5460 |
RPA3,RP2,RIGI,CRYZ,PAQR3,TIMMDC1,CENPM,GBE1,TOP3B,COMTD1,RAF1,ISG15,SNRNP27,NHERF1,PIR,LMNA,RPA2,SDCBP,RDH12,METAP2,CHAC2,THAP8,NUP35,FERMT2,MYG1,RAB11A,PDIA3,RAB2A,MOV10,AR,YWHAB,NQO1,SORD,DNAJB6,OSGEP,CA2 |
| 1.163e-02 | -4.45 | DGUOK (deoxyguanosine kinase) | protein interactions | 1716 | 91 | 36 | 19454 | 5460 |
GNG2,HPCA,MTPN,SNAP91,SYP,ELAVL4,TST,STX1A,CRMP1,CDH13,RAB3A,GNAO1,DCK,RAB14,SNAP25,SH3BGRL,H1-5,ATP6V1C1,NCALD,PPP1R8,SNCB,GLRX5,HPCAL1,STXBP1,VAMP2,RAB6B,MAP2K1,GNAQ,GRIA2,GPM6B,COA4,CAMKV,CNTN1,L1CAM,GPM6A,PHYKPL |
| 1.163e-02 | -4.45 | AKAP17A (A-kinase anchoring protein 17A) | protein interactions | 8227 | 94 | 37 | 19454 | 5460 |
RAF1,CSNK1E,H1-3,THAP1,CAAP1,RPL26L1,ZRANB2,RPLP0,ZC3H11A,UFL1,SRSF4,AHCYL1,MDFI,MYC,ZCCHC10,YWHAG,CSNK2A1,CCDC85B,CEP70,DDRGK1,DDX23,NOS1AP,BRD3,TSNAX,DLST,SRSF1,EIF4A3,CSNK2B,UBE2I,EIF4A2,RPL35,SNRNP40,NKAP,LYAR,SRPK2,TRAF1,ESR2 |
| 1.163e-02 | -4.45 | NPHP1 (nephrocystin 1) | protein interactions | 4867 | 94 | 37 | 19454 | 5460 |
BAG2,TMEM256,RPAP3,DNAAF10,SRSF2,UNC45A,PDRG1,WDR83,HSDL2,RAB6A,IDH3B,NUDCD3,UQCRC1,KDELR2,NDUFS3,PAK2,PIH1D1,DNM2,RAB35,MOB4,FCHO2,TUBB,AGK,RPGRIP1L,PRRC2A,TMEM237,SEC63,DBT,CACYBP,FBXO7,FKBP4,ECD,CHTOP,PSMD7,PSMD14,CBL,DNAJC7 |
| 1.163e-02 | -4.45 | EIF1AD (eukaryotic translation initiation factor 1A domain containing) | protein interactions | 84285 | 94 | 37 | 19454 | 5460 |
PAX6,STX11,ZBTB14,KRAS,CAMKV,CCDC106,PICK1,POLD2,CASK,CSNK1G3,RPS11,RBPJ,GNB1L,HEXIM1,PALS2,TNNI1,SDCBP,MND1,MREG,DLG3,CSNK1E,GTF2H4,TRMT1L,DPPA2,STAT1,IP6K1,RPS16,AP2M1,MGME1,MCAT,STN1,ATG3,TBC1D5,GAS8,UTP6,SUB1,MOV10 |
| 1.163e-02 | -4.45 | KANSL1 (KAT8 regulatory NSL complex subunit 1) | protein interactions | 284058 | 94 | 37 | 19454 | 5460 |
CCDC85B,EXOC1,CEP70,KANSL3,DPY30,BAZ1B,MDFI,MYC,HSPB1,TADA3,RPL37A,TRIM27,SMAD3,PNMA1,H2AZ1,TRAF1,VIRMA,CDC5L,BUB3,FZR1,ELF1,TRAF2,H2AX,TOP3B,NUP62,TFIP11,CDR2,DISC1,NLE1,HCFC2,CXXC1,PCGF6,RERE,RIGI,SGF29,ZNF609,KDM1A |
| 1.163e-02 | -4.45 | POC5 (POC5 centriolar protein) | protein interactions | 134359 | 94 | 37 | 19454 | 5460 |
TNFRSF1B,CALML5,TYMS,ANAPC2,CETN3,PRNP,AGK,CETN2,RAB2A,CSK,ATP5MG,XPO1,BICD2,PSMD14,CHTOP,SSX2IP,MED4,ZYX,SDHC,ABCE1,POC1B,BAG2,TRIM11,SRSF2,PRPS1,ATG16L1,NAA15,IPO8,FAM161A,IDH3B,AKIP1,KDELR2,UQCRC1,GFPT1,TFRC,MAP2K1,HAUS2 |
| 1.163e-02 | -4.45 | ARHGAP35 (Rho GTPase activating protein 35) | protein interactions | 2909 | 94 | 37 | 19454 | 5460 |
RND3,RND2,CDC42,TOP3B,BCL6,FTL,UCHL3,SRSF2,STAU1,BAG2,RPA3,CSTB,NME2,GLOD4,RHOG,CIRBP,RHOB,SNRNP70,CFL1,MTPN,AAMDC,STOML2,CHCHD3,VIRMA,ESR2,SRC,PTPRZ1,PRDX2,HNRNPL,PRNP,ACTB,RHOJ,GSK3A,RTRAF,RAC2,PSPC1,CTTN |
| 1.163e-02 | -4.45 | TSPYL2 (TSPY like 2) | protein interactions | 64061 | 94 | 37 | 19454 | 5460 |
ZFP1,RPLP0,CASK,APTX,CDK1,EZH2,MAGEA4,RPL15,RPL27A,CDK4,COIL,RPL4,NOP53,SNIP1,FGF3,PML,GRIA2,NOL12,BRD3,TMA16,CSNK2A1,PSMD3,CREBBP,LMO2,ZCCHC10,CCNB1,CUL3,ZNF687,KMT5B,DYRK1A,CEP19,HNRNPL,RPS16,RPL7,CSNK2B,PRKRA,CCNF |
| 1.163e-02 | -4.45 | WDFY3 (WD repeat and FYVE domain containing 3) | protein interactions | 23001 | 94 | 37 | 19454 | 5460 |
MYC,ATG9A,MOV10,MDFI,GPR17,EDEM1,PRMT6,RAB11A,PIK3R3,RAB5C,H2BC9,P2RY10,SUV39H1,BAG3,LACRT,TRAF6,PDCD1,ICAM1,CD79B,MAP1LC3A,BTG3,OPRL1,VIRMA,FAM234A,ATG16L1,TOP3B,MGARP,GABARAPL1,HCST,GABARAPL2,NFE2L1,AQP3,FURIN,FLCN,LCN1,SQSTM1,GABARAP |
| 1.164e-02 | -4.45 | cell cycle G1/S phase transition | biological process | GO:0044843 | 70 | 30 | 18204 | 5365 |
EZH2,CCND3,RB1,EIF4E,MYC,PIM2,CACUL1,ID4,CDKN1A,CUL2,MNAT1,MAP3K11,RBBP8,TAF10,CDK6,CCNA2,CDK4,CCND1,BTN2A2,PIAS1,CDKN3,HINFP,ACVR1B,RHOU,HSPA8,CDK1,PPP3CA,CUL3,CDKN1B,CDC7 |
| 1.164e-02 | -4.45 | intracellular iron ion homeostasis | biological process | GO:0006879 | 70 | 30 | 18204 | 5365 |
SMAD4,CYB561,PICALM,SOD1,SLC22A17,BOLA2B,FTHL17,FXN,ACO1,NDFIP1,BOLA3,HFE,FRRS1,ATP6V1G1,SRI,IREB2,FTH1,TFRC,TF,BOLA1,B2M,NEO1,TMEM199,CYBRD1,MYC,ISCU,GLRX5,SLC11A2,FTL,ATP6V1A |
| 1.164e-02 | -4.45 | RBBP4 (RB binding protein 4, chromatin remodeling factor) | protein interactions | 5928 | 551 | 179 | 19454 | 5460 |
NACC2,CTBP1,PPT1,UFL1,RNF5,SAP18,DDX39B,HIRA,HSPA8,HDAC5,YAF2,EP300,TFDP2,LAMTOR1,DNAJB6,H1-1,CREBBP,MYC,HNRNPC,BTF3,BRMS1,CPSF2,CBX5,PHF12,PRMT5,ZMYM2,MTA2,SMARCB1,SOX2,TUBA1A,ISG15,KRAS,RUVBL1,RUVBL2,IFI16,LAMP2,WWP2,DDRGK1,HNRNPL,SUMO2,DYNC1I2,HMG20A,CCDC71,SIN3A,S100A8,ZHX1,EED,RPA2,HEXIM1,UBE2M,ACACA,PPP1R8,CFTR,HDAC3,KDM1A,HSPA5,BAP1,BANF1,RNF113A,SPOP,ZBTB38,UBE2H,SMARCA5,MTPN,ADRM1,CREB1,ING2,CSNK2B,CBX3,NKX3-2,CHAMP1,RNF8,NUPR1,TP53,ACTR1A,ZMYM3,H3C1,KPNA2,MEPCE,PHF1,KPNA1,USP15,CD81,CSNK2A1,FZR1,BRMS1L,SHPRH,CDC5L,GATAD1,ANXA7,ACTL6A,WDR77,CDKN1A,TGIF2LX,FAS,BRCA1,HSP90AA1,SP1,RIT1,DSN1,CUL3,PROX1,SMARCE1,MCM3,PRDX2,RBBP4,ACTB,BAD,RAN,FAM43A,EZH2,RPN1,RAF1,ZNF263,E2F4,SAP30,RBBP7,G3BP1,CDK20,ASF1A,UBE2A,SSRP1,RAD21,HMGA1,PDIA3,PSMD3,DPY30,PHB1,ATP6V1A,COPS2,LMNA,DCTN4,RPLP0,ATG16L1,PSMC4,CCND1,NF2,GTF2I,FBXW7,SMC4,NUCKS1,MBD3,RPA3,SIRT7,MIS12,PPTC7,FBXO7,HMOX2,DNAJC8,KPNA6,NDN,EAF2,VIRMA,CCNF,EZH1,ACTR2,TOPORS,SAP30L,MTA3,PHF23,ING1,MAP2K3,EXOSC8,GGCT,HUWE1,FN3KRP,CDK2AP2,THRAP3,SMN1,EPOP,RNF14,TLE1,HDAC6,SUV39H1,TOP1,ZBTB2,H2AZ1,MYBL2,RB1 |
| 1.166e-02 | -4.45 | modulation by host of symbiont process | biological process | GO:0051851 | 87 | 36 | 18204 | 5365 |
CX3CR1,RAB29,PHB1,CDC42,PAIP1,NUCKS1,CCL5,NLRP6,ZBED1,TAF11,IFI27,SAP30,EP300,PC,ROCK2,SMARCB1,CAV2,CDK9,MIR221,EEF1A1,PSMC3,CCL8,SP1,APOBEC3H,CFL1,STOM,JUN,ZDHHC8,CCL3,RAB9A,MIR222,PPIB,HSPA8,SAP30BP,INPP5K,RAB5A |
| 1.166e-02 | -4.45 | endothelial cell differentiation | biological process | GO:0045446 | 87 | 36 | 18204 | 5365 |
ICAM1,CLIC4,EDNRA,RBPJ,PDE2A,NRP1,STC1,EDF1,GSTM3,FSTL1,TMEM100,GPX1,RAP1B,BMPR2,CCM2,RAP1A,RAB1A,HAPLN2,MYD88,FOXP3,RAB1B,ACVR1,NDP,RAP2C,RAP2B,MET,F11R,PROX1,SMAD4,MSN,LIPA,CLDN3,FZD4,CLDN1,HEY2,CXCR4 |
| 1.178e-02 | -4.44 | KRT2 (keratin 2) | protein interactions | 3849 | 212 | 75 | 19454 | 5460 |
KCTD9,NDN,MTM1,VIRMA,CEP97,CCNF,RNF208,EIF4A3,AP2M1,IFT172,UBASH3B,RC3H2,UBE2H,PRSS1,MYC,CUL3,SFN,CUL2,UFL1,ADRB2,PIK3R2,FBXL4,DDX39B,INPPL1,BAP1,NMRAL1,CRY1,RNF113A,VPS18,METTL14,HEXIM1,WTAP,PIH1D1,CFTR,CAND1,INA,DCUN1D1,SNX18,MDM2,CDK9,NUF2,KIAA0232,SMAD3,EFNA3,PHB1,EED,ARL4D,TRAF6,SHC1,POU5F1,CBL,MAGOH,DPP4,DIRAS2,EMC4,HDAC6,HNRNPA1,COPS5,DDRGK1,NEDD8,LASP1,TNF,TRIM37,MEPCE,FAF1,EWSR1,EZH2,RNF8,TBK1,FBP1,KBTBD4,TP53,INSIG2,MAP1LC3B,LGR4 |
| 1.179e-02 | -4.44 | ZFC3H1 (zinc finger C3H1-type containing) | protein interactions | 196441 | 171 | 62 | 19454 | 5460 |
MRPS7,ZDHHC17,STAU1,RPL4,PPP2R3A,PSENEN,C1D,EXOSC4,DDX39B,RPA3,SNRPA,GRM2,ZNF326,GRIK1,RPA2,SUFU,H1-5,SYK,ESR2,VIRMA,SRPK2,RPL13A,SNRNP40,BUB3,FGFBP1,TRIM27,VPS72,ZNF330,MCAT,EXOSC1,MRPS25,RBM27,CCDC85B,SRGN,TBC1D1,PPP1CC,CEP70,ANAPC15,TBCE,PRMT6,SSRP1,UNC119B,HNRNPK,RTCB,VPS26B,MRPS11,HAPSTR1,TMEM14B,LGR4,ACTR1A,RPAP2,MRPS23,NCBP2,THOC1,MPHOSPH6,ANKRD50,DDRGK1,TPM3,INSYN1,CSNK2A1,MRPS35,MOV10 |
| 1.180e-02 | -4.44 | Golgi-associated vesicle | cellular component | GO:0005798 | 94 | 38 | 19108 | 5553 |
DIPK2A,COPE,AP1G2,CHIC2,BACE1,RAB8B,KDELR1,STK16,SPPL3,AFTPH,CFTR,TMEM199,SCFD1,OCRL,KDELR2,USE1,NCALD,AP2A1,AP1M1,ITM2B,RAB13,AP1S2,TMED7,COPZ2,STK26,GPR89A,SYNRG,TMED9,SPG21,ARCN1,CLRN1,GJA1,TMED3,RAB14,FURIN,CIDEB,CLBA1,ZDHHC17 |
| 1.181e-02 | -4.44 | G1 to S cell cycle control | WikiPathways | WP45 | 68 | 34 | 5310 | 1910 |
MYC,ORC6,MCM3,POLA2,CDKN2D,CCND1,RPA3,TFDP2,CDK4,ORC5,MDM2,CDK6,PRIM2,RB1,TP53,MNAT1,CCND3,RPA2,PCNA,MCM4,CDK1,CREB1,CREB3,CDKN1B,CREB3L4,CDKN2C,GADD45A,CCNH,E2F6,E2F4,CCNB1,CDK7,MCM6,CDKN1A |
| 1.182e-02 | -4.44 | Oxidative phosphorylation | WikiPathways | WP623 | 54 | 28 | 5310 | 1910 |
NDUFB4,ATP5PD,NDUFB7,ATP6AP2,ATP5PO,NDUFA4,ATP5F1A,ATP5MG,ATP5MC1,NDUFC2,NDUFB10,NDUFB8,NDUFA5,NDUFB6,NDUFA2,ATP5F1B,NDUFS2,ATP5MC3,ATP5F1D,NDUFV2,ATP5PB,ATP5PF,NDUFB5,ATP5F1E,NDUFS3,NDUFS8,NDUFS6,NDUFAB1 |
| 1.184e-02 | -4.44 | UBQ | smart domains | SM00213 | 41 | 18 | 9717 | 2575 |
UBTD1,TMUB2,UBB,UBLCP1,FAU,SF3A1,RPS27A,NEDD8,UBFD1,SUMO2,RAD23B,UBA52,UBL4A,SUMO3,USP14,ISG15,DDI1,SUMO1 |
| 1.186e-02 | -4.44 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1881 | 583 | 16828 | 4835 |
FGFR1,SHC1,CDKN1A,DIRAS2,MREG,OTUD7B,FAM161A,IGF1R,CX3CR1,LCP1,TACR3,HDAC11,LMO2,PSEN1,CRKL,SOS2,PPTC7,DIRAS3,YWHAH,GYS1,DYRK1A,BIRC2,RGL1,NCR3LG1,TSHR,NUDT5,IDH2,SS18,EIF2AK2,NDE1,RUNX1,SCML1,FBXO32,PRKCB,PABPC5,TRIM27,ZFAND6,BMPR1B,ERAS,PSMD1,SPRY1,PPARG,CD46,WNT10B,TRIM37,TRAF6,HECW1,HMX1,PTPN1,FBXO11,ATP6V1D,GPR37,MYEF2,MGMT,MYD88,SPTAN1,NPY2R,FEN1,CSNK2B,ADRB1,FRMD8,RHOB,MAX,USP2,MYT1L,HEY2,G2E3,TRIM11,PRKACB,GRM8,MEF2C,RAB2A,RIT1,CCNF,RAB9A,BAP1,FZD4,B4GALT3,AR,GPBP1L1,IL1B,EP300,ADRB3,FGF12,EZH2,EXOC1,CCND3,RAB9B,PEA15,IRF4,STK11,FGF3,FGF1,MAP2K1,WIF1,LAMTOR3,MLF1,STAT6,NUP62,COPS5,STAT5A,TRIM26,JAK1,FEZ1,USP13,DDIT3,DLGAP4,JOSD1,EIF4B,KIT,RASL12,RAP2C,ZNRF1,CD52,KLHL24,PPP2CB,PPP2R1A,GRSF1,STK38L,CSNK2A1,TTL,CCR7,NMBR,IGF1,USP3,MBD3,USP30,EXT1,JUNB,BRAP,RNF182,TNFRSF1B,TGFBR2,FASLG,STK38,TCEA1,CYP27A1,RAF1,CDC73,ZMYM2,MCHR2,DET1,VCPIP1,RAB5C,RASL11A,CBFB,ASPM,LTBR,OGG1,LTA,CCR3,TFPT,RAB23,CMAS,RIT2,ELMO1,DDR1,PTGER1,UBE2A,CBLN4,GHR,POLB,WWP1,SOCS4,S100B,P2RY1,JUN,PIAS1,UBE3A,SPHK2,IGFBP3,FBXL7,GRPR,PCMTD1,TGFB2,STYK1,MAP2K3,NRP1,MAP2K6,ANAPC11,TNKS,CD79B,ZBTB16,LAMTOR2,FOS,ITK,FAM8A1,CYP1A1,PPP2R2C,TMEM106B,STK4,NEK2,VAV2,MAP3K3,NFKB1,TIAM1,SENP5,RHAG,GRM2,CTNNBL1,RAB5A,PRKAG1,TLR3,OGDHL,LHFPL2,TLR1,ADGB,NUFIP2,CCR5,PAX6,STAT1,DICER1,GNA11,PPP2R5A,FANCG,TLR7,POU5F1,AVPR1B,MSN,FGF16,SFN,RALA,MEF2A,TLR6,NKIRAS2,ACVR1C,IL1R2,EGFL7,NPY5R,P2RY4,CXCR4,GNRHR2,CDH7,TFG,ZNF770,RND3,TP53,CNTNAP1,FBXO22,PTGFR,CREB1,BTG1,MAEA,SOCS5,MDM2,USP14,RAN,SENP8,CXCR6,WDR83,CISH,POLR2B,APLNR,RRAS2,TLR9,COMTD1,RERG,IKBKB,SDHC,AKT1,MITF,NFKBIA,OR51E2,NUP153,DKK3,OTUD6A,HRAS,PPP1R11,MSH6,RAP2A,CD40,SLC6A2,SHOC2,TUBA1B,PPP1CB,LIG3,PRKCQ,TLR8,DAG1,PSMD7,SIN3A,DUSP6,CDK7,USP16,EFCAB7,EDNRA,PML,UNC79,TMOD3,SOX3,PTPN11,NOTCH2,PSMD14,VEGFA,YWHAB,NCKIPSD,CCR1,ACVR1,RASGRP3,CDK12,BAD,TIRAP,BCL2L1,AKR1E2,YWHAG,RNF115,CRHR1,FBXW7,PDCD10,EPHA4,POPDC2,PPP1CC,DUSP1,NPY1R,CREBBP,PTGER2,MYC,CD40LG,DIRAS1,NKIRAS1,HERC3,BMPR1A,HSD17B8,SPOP,USP15,OTUD6B,LPAR2,NTRK2,FRZB,CCND1,CASP4,CRLF3,CDC42,TERT,PTEN,DUSP10,MAP3K11,PIK3R3,CCNA2,SYK,VPS16,INPPL1,ST8SIA4,CAPN2,SLC35D1,YWHAZ,PSEN2,SRC,RASL10A,IDH1,NCK1,DUSP9,RBCK1,CTDSP1,STAMBP,RBPJ,CDKN1B,NLGN2,DEK,CXCR3,PTGER4,AGR2,GRM1,SDHB,EDEM3,SHPRH,CAV1,IL1A,MET,FZD6,HSP90AB1,ETV6,RGL2,S1PR4,RAP2B,ZBTB42,TNFAIP3,KCNH8,TRAF7,PPP1R3C,SFRP4,TLR10,RHOU,CCR2,USP8,PTK7,CCIN,GNAQ,ATF3,PMAIP1,LPAR6,SPRED1,NFE2L2,USP46,SMAD2,PIK3R2,ADRB2,SFRP1,USP39,WNT2,HTR1A,SPRED2,TLR4,ZNF668,MRPS18C,NT5DC1,TRIM36,CTSC,BIRC5,KLHL12,FGF23,JAK2,RANBP6,FLCN,USP38,HSPB2,ADRA1A,PEBP1,STK3,FGF13,FGF22,FZD3,TOP1,CHST2,SMURF1,GMNN,RB1,UBE2N,CTNNB1,SOCS2,RALB,PNMA3,CDK6,NCSTN,ANXA7,P2RY10,TACR1,SCLT1,PPP2R5E,FGF7,CAV3,PARP2,EPHA2,NF2,HSPA13,TNF,APH1A,MAD2L2,FAS,CCDC25,WNT7A,ATF1,CCR4,ERCC3,GRB10,HECTD1,CSNK1E,ELK3,OR2J3,TGFB3,TRIM24,KDM2A,FGF10,GANAB,RPS6KA4,TLR2,PAK6,HSPB1,ZKSCAN1,EWSR1,STAMBPL1,RHEB,AKT3,BCKDK,PRKCE,PIK3R1,TFEB,RNF126,PIK3CG,LRRC1,EIF4E,XRCC5,RHOH,CDKN2C,USP5,GNAO1,PPP2R3A,IRAK4,SMAD4,FHOD3,IL2,BAK1,IGFBP4,NBN,ELK4,PI16,CBL,RTKN,NTN4,CDC7,WWP2,RAP1B,GTF2E1,RAP1A,UBE2V2,RBBP8,ACVR1B,MRAS,FGF17,CXCR1,CSNK1A1,DDI1,TFE3,ELK1,FOSL2,STAT2,SAV1,DKK1,HERC4,PRKAB1,HECTD3,HDAC5,RC3H2,CNTN1,KRAS,GSK3A,PRCC,BCL6,PRKCA,PPP1R1B,BMPR2,SOCS3,BCL9,PARP11,NLRP3,MAP1B,KLHL26,HSP90AA1,UCHL3,RASD1,TRAPPC4,POR,STK24,THRAP3,NFKBIB,EXOC2,RAC2,CAND1,LRP6,DVL2,P2RY12,PICALM,CDK4,APEX1,NTRK3,GAB1,LASP1,AKT2,BRCA1,TLR5,RAPGEF5,TPD52,TRAF2,BCL10,MBD5,BAX,GH1,ANKIB1,PDIA2,IVNS1ABP,PIK3CA,CDH11,SMARCB1,EFHD1,MNAT1,TNFSF10,FURIN,FBXL19,APEX2,SUFU,TAB1,UBE2B,CHIC2 |
| 1.186e-02 | -4.44 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1881 | 583 | 16828 | 4835 |
NRP1,MAP2K6,MAP2K3,STYK1,PCMTD1,TGFB2,ANAPC11,SPHK2,FBXL7,GRPR,IGFBP3,SOCS4,S100B,WWP1,POLB,GHR,UBE2A,CBLN4,UBE3A,PIAS1,P2RY1,JUN,LTA,OGG1,CCR3,RASL11A,CBFB,LTBR,ASPM,PTGER1,ELMO1,DDR1,RAB23,CMAS,RIT2,TFPT,MEF2A,RALA,SFN,IL1R2,NKIRAS2,ACVR1C,TLR6,DICER1,STAT1,PAX6,FGF16,MSN,POU5F1,AVPR1B,TLR7,FANCG,GNA11,PPP2R5A,RAB5A,PRKAG1,RHAG,GRM2,CTNNBL1,SENP5,MAP3K3,NEK2,VAV2,TIAM1,NFKB1,CCR5,NUFIP2,ADGB,TLR1,OGDHL,TLR3,LHFPL2,FAM8A1,CYP1A1,FOS,ITK,LAMTOR2,CD79B,TNKS,ZBTB16,STK4,TMEM106B,PPP2R2C,OTUD6A,NUP153,DKK3,MSH6,RAP2A,HRAS,PPP1R11,TLR9,APLNR,RRAS2,MITF,NFKBIA,OR51E2,AKT1,IKBKB,SDHC,COMTD1,RERG,SOCS5,MAEA,CREB1,BTG1,POLR2B,CISH,CXCR6,WDR83,SENP8,USP14,RAN,MDM2,GNRHR2,CDH7,P2RY4,CXCR4,NPY5R,EGFL7,FBXO22,PTGFR,CNTNAP1,TFG,ZNF770,RND3,TP53,YWHAB,NCKIPSD,PSMD14,VEGFA,CCR1,EFCAB7,NOTCH2,PTPN11,UNC79,PML,TMOD3,SOX3,EDNRA,DAG1,USP16,SIN3A,DUSP6,CDK7,PSMD7,TUBA1B,SHOC2,SLC6A2,CD40,PRKCQ,TLR8,LIG3,PPP1CB,RUNX1,EIF2AK2,SS18,NDE1,ZFAND6,TRIM27,PABPC5,PRKCB,FBXO32,SCML1,RGL1,DYRK1A,BIRC2,IDH2,TSHR,NUDT5,NCR3LG1,YWHAH,DIRAS3,PPTC7,SOS2,CRKL,PSEN1,HDAC11,LMO2,TACR3,GYS1,MREG,CDKN1A,SHC1,DIRAS2,FGFR1,LCP1,CX3CR1,FAM161A,IGF1R,OTUD7B,RHOB,MAX,MYT1L,USP2,FRMD8,FEN1,CSNK2B,ADRB1,PRKACB,TRIM11,G2E3,HEY2,MYD88,MGMT,MYEF2,GPR37,ATP6V1D,NPY2R,SPTAN1,PTPN1,HMX1,TRAF6,HECW1,WNT10B,TRIM37,FBXO11,ERAS,BMPR1B,PPARG,CD46,PSMD1,SPRY1,FGF1,MAP2K1,WIF1,STK11,FGF3,FEZ1,USP13,JAK1,NUP62,TRIM26,STAT5A,COPS5,LAMTOR3,MLF1,STAT6,EXOC1,EZH2,ADRB3,FGF12,EP300,IRF4,PEA15,RAB9B,CCND3,FZD4,BAP1,GPBP1L1,IL1B,B4GALT3,AR,RAB9A,RIT1,CCNF,MEF2C,RAB2A,GRM8,RAF1,CDC73,ZMYM2,TCEA1,STK38,CYP27A1,RAB5C,VCPIP1,MCHR2,DET1,JUNB,USP30,EXT1,MBD3,USP3,TGFBR2,FASLG,TNFRSF1B,RNF182,BRAP,CSNK2A1,GRSF1,STK38L,NMBR,IGF1,CCR7,TTL,JOSD1,EIF4B,DLGAP4,DDIT3,PPP2R1A,KLHL24,PPP2CB,CD52,KIT,RAP2C,ZNRF1,RASL12,RHEB,STAMBPL1,EWSR1,ZKSCAN1,TFEB,PIK3R1,PRKCE,AKT3,BCKDK,ELK3,OR2J3,HECTD1,CSNK1E,GRB10,HSPB1,PAK6,GANAB,FGF10,RPS6KA4,TLR2,TGFB3,TRIM24,KDM2A,MAD2L2,TNF,APH1A,CCR4,ERCC3,CCDC25,FAS,WNT7A,ATF1,SCLT1,TACR1,HSPA13,CAV3,PARP2,EPHA2,NF2,PPP2R5E,FGF7,CXCR1,FGF17,ACVR1B,MRAS,RBBP8,TFE3,ELK1,STAT2,SAV1,FOSL2,CSNK1A1,DDI1,RTKN,CDC7,NTN4,UBE2V2,RAP1A,GTF2E1,WWP2,RAP1B,SMAD4,FHOD3,IRAK4,PPP2R3A,ELK4,PI16,CBL,IGFBP4,BAK1,NBN,IL2,PIK3CG,RNF126,USP5,GNAO1,CDKN2C,XRCC5,RHOH,LRRC1,EIF4E,EXOC2,RAC2,NFKBIB,STK24,THRAP3,DVL2,LRP6,CAND1,PARP11,BMPR2,SOCS3,BCL9,PRKCA,PPP1R1B,RASD1,UCHL3,TRAPPC4,POR,KLHL26,HSP90AA1,NLRP3,MAP1B,PRCC,BCL6,KRAS,GSK3A,HERC4,DKK1,CNTN1,HDAC5,RC3H2,PRKAB1,HECTD3,UBE2B,SUFU,APEX2,TAB1,FBXL19,CHIC2,CDH11,SMARCB1,EFHD1,PIK3CA,IVNS1ABP,TNFSF10,FURIN,MNAT1,GH1,BAX,MBD5,BCL10,PDIA2,ANKIB1,LASP1,GAB1,NTRK3,AKT2,APEX1,CDK4,PICALM,P2RY12,TRAF2,TLR5,BRCA1,RAPGEF5,TPD52,LPAR2,OTUD6B,USP15,SPOP,CASP4,FRZB,CCND1,NTRK2,CD40LG,DIRAS1,NKIRAS1,MYC,PTGER2,HSD17B8,BMPR1A,HERC3,POPDC2,EPHA4,PDCD10,CREBBP,NPY1R,DUSP1,PPP1CC,BAD,CDK12,ACVR1,RASGRP3,CRHR1,FBXW7,BCL2L1,AKR1E2,RNF115,YWHAG,TIRAP,CXCR3,CDKN1B,NLGN2,DEK,SHPRH,EDEM3,AGR2,GRM1,SDHB,PTGER4,RBCK1,DUSP9,STAMBP,RBPJ,CTDSP1,SRC,PSEN2,SLC35D1,YWHAZ,ST8SIA4,CAPN2,INPPL1,NCK1,IDH1,RASL10A,DUSP10,PTEN,TERT,CDC42,CRLF3,VPS16,CCNA2,SYK,PIK3R3,MAP3K11,NFE2L2,ATF3,LPAR6,PMAIP1,SPRED1,CCIN,GNAQ,USP46,SMAD2,CCR2,RHOU,TLR10,PTK7,USP8,KCNH8,ZBTB42,TNFAIP3,RAP2B,RGL2,S1PR4,SFRP4,PPP1R3C,TRAF7,IL1A,CAV1,ETV6,HSP90AB1,MET,FZD6,ANXA7,NCSTN,CDK6,P2RY10,SMURF1,PNMA3,SOCS2,RALB,RB1,GMNN,UBE2N,CTNNB1,FGF22,FGF13,PEBP1,ADRA1A,STK3,HSPB2,CHST2,FZD3,TOP1,HTR1A,SPRED2,ZNF668,TLR4,WNT2,SFRP1,USP39,ADRB2,PIK3R2,USP38,JAK2,RANBP6,FLCN,CTSC,BIRC5,FGF23,KLHL12,NT5DC1,MRPS18C,TRIM36 |
| 1.188e-02 | -4.43 | DDB2 (damage specific DNA binding protein 2) | protein interactions | 1643 | 143 | 53 | 19454 | 5460 |
PDRG1,PTGES3,COPS4,PSMA5,H3C1,CRYBA4,KHDC1,TRIM21,PCNA,SPATA6,HSPD1,TOP2B,CCT8,TOPORS,DCUN1D5,EZH2,TPPP,ISG15,UBR7,CCT5,NTMT1,CCT7,COPS7B,TOP1,TCP1,PSMB1,COPS2,PSMB4,H2AC4,COPS5,PFDN5,EP300,XRCC5,BANF1,UBE2M,ARCN1,RPA2,RNF7,SUPT3H,PAQR3,GADD45G,ZBTB17,DCLRE1C,APEX2,PFDN4,COP1,DTL,PFDN2,CCT2,AR,CCNQ,MYC,COPS7A |
| 1.189e-02 | -4.43 | regulation of sodium ion transmembrane transporter activity | biological process | GO:2000649 | 48 | 22 | 18204 | 5365 |
MIR192,PCSK9,SLMAP,SCN3B,ACTN4,MIR24-1,CHP1,SCN2B,RANGRF,YWHAH,CAV3,FGF12,FGF13,FXYD6,MIR448,ATP1A2,HECW1,ATP1B1,PRKCE,TESC,SCN1B,NETO1 |
| 1.189e-02 | -4.43 | Malaria | KEGG pathways | hsa05144 | 49 | 25 | 7161 | 2463 |
SDC2,TGFB3,TGFB2,HBB,CD36,MET,IFNG,MYD88,IL10,TLR9,CD40,TLR2,IL12A,THBS3,CCL2,CD40LG,HBA1,CXCL8,TLR4,TNF,IL18,ICAM1,IL6,CD81,IL1B |
| 1.189e-02 | -4.43 | Malaria | KEGG pathways | ko05144 | 49 | 25 | 7161 | 2463 |
IL12A,ICAM1,IL18,TLR4,CXCL8,CD40LG,TGFB3,TGFB2,IFNG,MET,THBS3,TLR2,TLR9,CD40,IL10,CD81,IL1B,IL6,TNF,HBA1,CCL2,SDC2,MYD88,HBB,CD36 |
| 1.192e-02 | -4.43 | PPP1R3A (protein phosphatase 1 regulatory subunit 3A) | protein interactions | 5506 | 53 | 23 | 19454 | 5460 |
UBXN2B,PPP1CB,PPP1CC,CCDC85B,PPP1R8,PLN,PFDN2,PFDN6,PIH1D1,PPP1R11,SHOC2,TOX4,BRCA1,RPAP3,RUVBL2,WDR82,NUP50,EP300,PPP1R10,PDRG1,PPP1R2,PPP1R18,DNAAF10 |
| 1.192e-02 | -4.43 | GALE (UDP-galactose-4-epimerase) | protein interactions | 2582 | 53 | 23 | 19454 | 5460 |
BAG3,EEF2,GALE,POP5,CD2AP,SOX2,GFUS,RAF1,RIT1,DNAJB6,AHSA1,HSP90AA1,CA14,ARMC1,KLHL24,ARF1,HSP90AB1,WIF1,MAT2B,ETFA,SPPL3,KRAS,DCUN1D1 |
| 1.192e-02 | -4.43 | CDA (cytidine deaminase) | protein interactions | 978 | 53 | 23 | 19454 | 5460 |
PYM1,CDKN2C,GPX4,ARRDC3,CPNE1,PSMA1,KPNA2,CLIC4,G6PD,FNDC11,LYPLA1,DDIT4L,MTMR6,GBE1,NTAQ1,XPO1,KRTAP8-1,TIMM8A,GORASP2,SDCBP,PALS2,ZMYM6,RNF181 |
| 1.192e-02 | -4.43 | SUMF2 (sulfatase modifying factor 2) | protein interactions | 25870 | 53 | 23 | 19454 | 5460 |
FBXW7,ZDHHC17,CLU,SOD1,TMEM106B,COA4,LYPLA1,B3GNT2,E2F4,TUBA1A,H2AX,CDK7,TXNDC12,APEX1,EFNA3,LMBR1L,FUBP3,SEC61B,FAHD1,AK2,CALU,AK3,LYPLAL1 |
| 1.192e-02 | -4.43 | KCNB2 (potassium voltage-gated channel subfamily B member 2) | protein interactions | 9312 | 53 | 23 | 19454 | 5460 |
AMIGO1,GJA1,RHOH,DIRAS3,LMAN1,KCNG3,RAB11A,LAMP2,RAB2A,LAMP3,KCNB1,TMT1A,DERL1,KRAS,FLOT1,STX7,BET1,DDX39A,RND2,SEC62,RPN1,KCNF1,RND3 |
| 1.192e-02 | -4.43 | CCNT2 (cyclin T2) | protein interactions | 905 | 53 | 23 | 19454 | 5460 |
MACROH2A2,TAF2,NUFIP2,HEXIM1,SNRNP70,TOX4,DDX42,RBM15B,PPIL4,SUPT5H,UBA52,ESR2,G3BP2,PPP1R10,CDK9,MEPCE,SNRNP40,UFL1,CDK6,RB1,HEXIM2,WDR82,CTTN |
| 1.195e-02 | -4.43 | ACBD7 (acyl-CoA binding domain containing 7) | protein interactions | 414149 | 13 | 8 | 19454 | 5460 |
OGDHL,GNAZ,SRC,YES1,HPCAL1,TBC1D24,ACOX1,SUGP1 |
| 1.195e-02 | -4.43 | asp (Asp) | protein interactions | 19424028 | 13 | 8 | 19454 | 5460 |
NFKB1,TNF,BECN1,MAP1LC3B,MAP1LC3A,IL2,SQSTM1,IFNG |
| 1.195e-02 | -4.43 | CRYGC (crystallin gamma C) | protein interactions | 1420 | 13 | 8 | 19454 | 5460 |
HSPB2,CRYGB,CRYBB2,CRYGD,TP53,HSPB1,CRYAB,DISC1 |
| 1.195e-02 | -4.43 | Trappc11 (trafficking protein particle complex 11) | protein interactions | 320714 | 13 | 8 | 19454 | 5460 |
TRAPPC2L,ATG3,FBXO30,TRAPPC6A,NUDT18,VDAC2,TRAPPC1,TRAPPC3 |
| 1.195e-02 | -4.43 | RNU6ATAC (RNA, U6atac small nuclear) | protein interactions | 100151684 | 13 | 8 | 19454 | 5460 |
PRPF31,PRPF4,VIRMA,SNRNP40,LSM2,DDX23,USP39,LSM4 |
| 1.195e-02 | -4.43 | CCDC9B (coiled-coil domain containing 9B) | protein interactions | 388115 | 13 | 8 | 19454 | 5460 |
CIAO1,DDX39B,SOX2,STAU1,DCAF4,THOC1,G3BP1,RIGI |
| 1.195e-02 | -4.43 | ANO8 (anoctamin 8) | protein interactions | 57719 | 13 | 8 | 19454 | 5460 |
RPA3,TOP3B,ADRA1A,OTULINL,SEC61B,RPA2,HNRNPL,SSR1 |
| 1.195e-02 | -4.43 | NEK10 (NIMA related kinase 10) | protein interactions | 152110 | 13 | 8 | 19454 | 5460 |
PFDN5,DDX39A,PFDN4,PFDN2,PFDN1,PFDN6,USP15,HSPB1 |
| 1.195e-02 | -4.43 | HRH1 (histamine receptor H1) | protein interactions | 3269 | 13 | 8 | 19454 | 5460 |
VIRMA,IL6,MAT2B,CD81,YIPF3,LIMS2,DHRS7,SLC43A2 |
| 1.195e-02 | -4.43 | MRNIP (MRN complex interacting protein) | protein interactions | 51149 | 13 | 8 | 19454 | 5460 |
PKIA,PSMB1,EFHC1,PICK1,MIF,EIF3E,ENKD1,ZDHHC15 |
| 1.195e-02 | -4.43 | TAS1R3 (taste 1 receptor member 3) | protein interactions | 83756 | 13 | 8 | 19454 | 5460 |
STIM1,TMEM11,VIRMA,ACP2,LRRC3,HYAL2,GJA1,TAS1R2 |
| 1.195e-02 | -4.43 | XRN1 (5'-3' exoribonuclease 1) | protein interactions | 54464 | 244 | 85 | 19454 | 5460 |
MFSD5,RPL8,SYNCRIP,SDHB,ARL10,PSMB5,FUBP3,ALYREF,MIR429,EGLN3,NUP35,RPS16,YWHAH,CPEB1,XPO1,HNRNPA1,EDC3,IFI16,SSX2IP,MED4,RPL10A,TUBG1,ADPRH,RPL3,ZC3H7A,HNRNPA2B1,FGF3,LSM14A,RPS4X,RPS13,TMEM50A,LSM4,TRIM37,SOX2,RPS7,EXOSC8,TOP3B,KBTBD4,MTCH2,YTHDF2,CCT5,GTPBP1,DXO,RNF187,PRKRA,AP1G2,POLR3H,PHF21A,CCNF,PSPC1,CBX5,PRRC2A,VIRMA,ESR2,DYRK1A,CEP97,LDHA,CTSB,COPE,RPL13A,ZNF668,FBXO7,NDUFB10,MYC,EXOSC1,TLR9,EXOSC4,MIR34C,SMG5,RPA3,POLD2,UPF3B,SIRT7,PSMC1,RNF41,KDM1A,NPM3,STAU1,RPL4,AGO1,RPLP0,LEPR,ZNF574,MIR7-1,RPA2 |
| 1.196e-02 | -4.43 | chordoma | COSMIC cancer mutations | chordoma | 25 | 13 | 16828 | 4835 |
KRAS,HRAS,IDH1,SS18,TP53,CTNNB1,KIT,IDH2,JAK2,PIK3CA,TERT,SMARCB1,PTEN |
| 1.205e-02 | -4.42 | G alpha (z) signalling events | REACTOME pathways | R-HSA-418597 | 48 | 23 | 10285 | 3229 |
GNG2,GNAI2,GNG12,ADCY3,PRKCB,GNB3,PRKCE,GNGT2,GNAZ,MIR197,RGS19,GNAI3,GNG3,GNG13,PRKCA,ADCY2,GNB1,GNG10,GNG7,GNB4,PRKCQ,GNG11,GNG5 |
| 1.205e-02 | -4.42 | AP3D1 (adaptor related protein complex 3 subunit delta 1) | protein interactions | 8943 | 140 | 52 | 19454 | 5460 |
EGLN3,PEG10,STX6,VAMP7,CEP19,SPPL3,ARF6,POU5F1,AGR2,XPO1,DDRGK1,ATG9A,TSPAN10,ZCCHC10,ARF4,CAMKV,VPS33A,RAB4A,TOP3B,RAF1,TP53,VIRMA,FBXO22,GSK3A,ARF1,OPTN,CCNF,DLST,CDC73,UBE2H,AP3S2,LAMTOR1,DNAJC5,VPS39,MYC,WDR55,FTL,UFL1,FBXW7,STAU1,HSPA8,SQSTM1,COMMD2,BAP1,RPA3,SOD1,PML,KLC2,RPA2,CDC42,NEK7,CFTR |
| 1.205e-02 | -4.42 | PTPRO (protein tyrosine phosphatase receptor type O) | protein interactions | 5800 | 140 | 52 | 19454 | 5460 |
HSPA5,UFL1,EMC1,MAIP1,DNAJC3,RAB29,FKBP10,MET,MMP14,TMX4,GTF2IRD1,SYK,TOR1AIP2,PGRMC1,ATP6AP2,LGALS3,TXNDC12,GANAB,XPOT,CNIH4,EPHA2,SPCS3,SDF2L1,YWHAZ,DNAJC10,PSMD1,CNNM4,PSMD12,RIGI,LAMB2,KIT,PGAP4,ERLEC1,SRPRB,DNAJC30,ERO1A,MAN1A2,PDIA6,SELENOF,PSMC3,TFRC,MAD2L1BP,NCSTN,LMAN1,OS9,CORO1C,PTK7,UBE2G2,PPIB,CALR,PDIA3,SEC61A2 |
| 1.205e-02 | -4.42 | PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma) | protein interactions | 79837 | 140 | 52 | 19454 | 5460 |
DCAF16,PIP4K2C,RHOB,UBE2H,STK11,MYC,ST13,MTPN,RIOK2,SYT2,CAB39,CSNK2B,CDK1,CSNK1A1L,JUP,PSMB7,CSNK1A1,ZNF428,NF2,SKP1,ATG4C,POLA2,DVL2,RPA3,FLCN,NOS1AP,DDX23,YWHAB,BRD3,MED4,ZCCHC10,EDEM1,KARS1,CSNK2A1,DCUN1D1,WIF1,WDR44,ACTR2,TNFAIP8L1,ZRANB2,GPBP1L1,TP53,MAX,KIF2A,TULP3,CAMKV,AHCYL1,FBXO25,HSPD1,HSD17B10,POC1B,RPAP3 |
| 1.205e-02 | -4.42 | somatic diversification of immunoglobulins involved in immune response | biological process | GO:0002208 | 27 | 14 | 18204 | 5365 |
SWAP70,CCR6,STAT6,MSH6,RNF8,SHLD1,NBN,EXOSC3,BATF,CD40LG,MAD2L2,HSPD1,BCL6,FOXP3 |
| 1.205e-02 | -4.42 | positive regulation of vascular endothelial cell proliferation | biological process | GO:1905564 | 27 | 14 | 18204 | 5365 |
MIR29A,MIR135B,MIR21,MIR126,MIR130A,SP1,APLN,MIR132,AKT3,PROK1,GHRL,HMGB1,MIR495,FGFR1 |
| 1.206e-02 | -4.42 | ribosomal large subunit assembly | biological process | GO:0000027 | 22 | 12 | 18204 | 5365 |
RPL10,PPAN,NOP53,RPF2,NLE1,TRAF7,MRM2,BRIX1,RPLP0,RPL10L,RPL23A,RPL6 |
| 1.206e-02 | -4.42 | gas transport | biological process | GO:0015669 | 22 | 12 | 18204 | 5365 |
BPGM,HBB,RHAG,RHCG,RHBG,CYGB,HBA1,HBM,CA2,IPCEF1,HBE1,NGB |
| 1.206e-02 | -4.42 | nuclear membrane | cellular component | GO:0031965 | 314 | 110 | 19108 | 5553 |
SEPHS1,BCL2L1,HACD3,H2BW1,TMEM168,CASC3,TMEM97,DNAJC1,CCND1,PSEN1,RB1CC1,NRM,MAD2L1BP,DNAJC2,SYNE4,HAX1,TOR1AIP2,GCHFR,MTDH,WTAP,PRNP,GLE1,RETSAT,PRICKLE2,TMX4,LBR,GNAQ,LMNA,C9orf72,PLPP6,CCNI,NUP42,SDCBP,SURF4,LMNB1,MYORG,ADRA1A,TRIM27,NUP50,KLK6,NUP62,IL15RA,TERB2,CPTP,INPP4A,SMAD3,IFI27,NOS1AP,NLRP6,SMAD1,TRA2B,NUDT1,RBMX2,TNKS,OSBPL8,ZMPSTE24,LEMD3,MX1,ARL6IP6,MRPS23,TMEM176B,NUDT9,SLC52A3,CDK4,MACO1,TMEM147,DMPK,NUP153,KCNH1,PLCB1,NOC4L,MINDY3,EI24,FAM169A,GTF3C3,APEH,TOR1B,PAFAH1B1,THAP7,SUMO1,MYO6,PTGDS,ANXA4,WDR3,STX1A,DNAJB2,ENO1,BOK,FZR1,MATR3,BRAP,TMEM38B,DTL,KPNA2,PAK5,NUP107,NUP35,GAPDH,XPO1,LYPLA1,CD38,ALOX5AP,PSEN2,CPNE1,SIGMAR1,CREB3L4,TENT4A,UNC50,CBX3,ZBED1 |
| 1.206e-02 | -4.42 | regulation of neuroinflammatory response | biological process | GO:0150077 | 40 | 19 | 18204 | 5365 |
TNFRSF1B,CD200R1,IGF1,CCL3,IL18,TNF,MIR206,MIR181C,LDLR,CTSC,IL1B,IL4,MIR195,IL6,CD200,MMP9,MIR142,NUPR1,STAP1 |
| 1.206e-02 | -4.42 | regulation of fibroblast growth factor receptor signaling pathway | biological process | GO:0040036 | 40 | 19 | 18204 | 5365 |
SPRY1,CTNNB1,MIR149,MIR16-1,NOG,MIR503,MIR1-1,FGFBP1,MIR424,SHISA2,MIR146A,GPC1,HHIP,OTX2,MIR573,DSTYK,NPTN,APLN,FAM20C |
| 1.207e-02 | -4.42 | Keratan sulfate biosynthesis | REACTOME pathways | R-HSA-2022854 | 28 | 15 | 10285 | 3229 |
B4GALT4,B4GALT6,ST3GAL2,CHST2,ST3GAL1,CHST1,B4GALT3,B4GAT1,B3GNT2,LUM,ST3GAL4,FMOD,OGN,B4GALT1,PRELP |
| 1.207e-02 | -4.42 | Adrenaline,noradrenaline inhibits insulin secretion | REACTOME pathways | R-HSA-400042 | 28 | 15 | 10285 | 3229 |
GNG5,GNG11,GNG10,GNG7,CACNB2,GNB4,GNB1,GNG13,GNG3,CACNB3,GNGT2,GNB3,GNAI2,GNG12,GNG2 |
| 1.207e-02 | -4.42 | COPI-independent Golgi-to-ER retrograde traffic | REACTOME pathways | R-HSA-6811436 | 28 | 15 | 10285 | 3229 |
DCTN3,PAFAH1B2,DYNLL1,PAFAH1B3,GALNT1,BICD2,DCTN4,DCTN6,GALNT2,RAB6A,RAB6B,DYNC1I1,PAFAH1B1,DYNC1I2,RAB18 |
| 1.207e-02 | -4.42 | SGK2 (serum/glucocorticoid regulated kinase 2) | protein interactions | 10110 | 39 | 18 | 19454 | 5460 |
HSP90AA1,RPS6KA4,CCT5,TPT1,PMM2,AKT3,AKT1,CCT7,HSP90AB1,TCP1,HNRNPL,SPPL3,DAPK1,DDX5,HAPSTR1,CCT8,AKT2,AIP |
| 1.207e-02 | -4.42 | RNF220 (ring finger protein 220) | protein interactions | 55182 | 39 | 18 | 19454 | 5460 |
CUL3,TP53,RPL27A,WDR5B,CTNNB1,PTGER4,UBE2E3,LMNB1,ZC4H2,GRIA2,GRIA1,UBE2D3,STAT1,CHCHD2,APEX1,DYRK1A,RIGI,UBE2L3 |
| 1.207e-02 | -4.42 | TMEM200A (transmembrane protein 200A) | protein interactions | 114801 | 39 | 18 | 19454 | 5460 |
STX7,STX6,GOSR1,CAMK2G,SLC31A1,TGFBR2,ACVR1B,TMEM268,ARRDC3,STX10,DDR1,BMPR1A,PPP3CA,AGR2,PPP3R2,IFNGR1,TP53,KLHDC8A |
| 1.207e-02 | -4.42 | ADK (adenosine kinase) | protein interactions | 132 | 39 | 18 | 19454 | 5460 |
RBM12,CSK,SRD5A3,ETFBKMT,CAPG,RPA2,PIR,AGR2,NQO1,UBE2H,RPA3,SOD1,TMSB4X,PITPNB,AIF1L,LDHA,WIF1,NUP35 |
| 1.207e-02 | -4.42 | IGSF21 (immunoglobin superfamily member 21) | protein interactions | 84966 | 39 | 18 | 19454 | 5460 |
MAD2L1BP,HSPB1,GZMK,SERPINB9,KRAS,NREP,UBE2V2,RPP14,GSTM4,PAEP,IGSF21,ERH,SEPHS1,PAFAH1B3,ATF3,TMSB4X,GADD45A,S100A8 |
| 1.207e-02 | -4.42 | COQ4 (coenzyme Q4) | protein interactions | 51117 | 39 | 18 | 19454 | 5460 |
RANBP10,POLDIP2,CHCHD2,MRPL23,YTHDF1,MKLN1,MRPL13,HSPD1,GID4,MAEA,GID8,ARMC8,MRPS16,HDAC6,APOBEC3F,TOP3B,ZMYND19,MRPS35 |
| 1.207e-02 | -4.42 | NAV2 (neuron navigator 2) | protein interactions | 89797 | 39 | 18 | 19454 | 5460 |
HRAS,VIRMA,FBXO22,KRAS,RBM15B,YWHAG,HDAC6,SOX2,YWHAH,ING5,SFN,MORF4L1,KXD1,TOP3B,MAPRE1,YWHAB,YWHAZ,CHMP4C |
| 1.207e-02 | -4.42 | DUSP29 (dual specificity phosphatase 29) | protein interactions | 338599 | 39 | 18 | 19454 | 5460 |
ARPC3,GPD2,NIF3L1,RB1CC1,EPHA2,POLR2G,DDIT4L,RNF40,NOC4L,SPPL3,PDHB,CNTROB,STX11,PSMB5,PTK7,ASPA,IGF1R,PICK1 |
| 1.213e-02 | -4.41 | IL-7 Signaling Pathway | WikiPathways | WP205 | 25 | 15 | 5310 | 1910 |
MYC,STAT5A,IL2RG,PIK3R1,STAT1,CCND1,JAK1,CDKN1B,IL7,BAD,PIK3R2,AKT1,IL2RA,BCL2L1,MAP2K1 |
| 1.214e-02 | -4.41 | regulation of leukocyte chemotaxis | biological process | GO:0002688 | 122 | 48 | 18204 | 5365 |
CCR7,CCR6,OXSR1,VEGFC,STAP1,GREM1,MPP1,CREB3,CCL3,MIF,RAC2,MMP28,HMGB1,IL12A,DDT,CXCL12,CX3CR1,IL6,CCN3,TNFAIP6,PADI2,DUSP1,MIR223,F7,GPSM3,CCL5,CXCL8,CALR,XCL1,DEFB124,CCR2,CCL19,AIF1,DPP4,CXCL13,PTN,CCL21,CCL1,RARRES2,VEGFA,CCR1,SWAP70,IL23A,MSTN,CCL2,CXCL10,TIRAP,IL34 |
| 1.215e-02 | -4.41 | regulation of heart growth | biological process | GO:0060420 | 73 | 31 | 18204 | 5365 |
MIR204,BMPR1A,PARP2,RBPJ,FOXP1,IGF1,DUSP6,MIR873,MEF2C,CAV3,VGLL4,WNT2,MIR1-1,GSK3A,SAV1,G6PD,RGS2,MIR25,CDK1,MIR222,PI16,MIR208A,FGFR1,RUNX1,MIR548C,PROX1,PPARA,TOMM70,MIR590,HEY2,NOG |
| 1.215e-02 | -4.41 | positive regulation of alpha-beta T cell activation | biological process | GO:0046635 | 73 | 31 | 18204 | 5365 |
PRKCQ,ZBTB16,IL12A,FOXP3,NLRP3,SYK,NKAP,SASH3,RUNX1,IL18,PNP,CD83,SOCS5,MIR21,KLHL25,CD81,LILRB4,CCL19,TGFBR2,CCR2,IL12B,XCL1,IFNG,EP300,JAK2,CD86,IL2RG,IL23A,CBFB,CD80,CD28 |
| 1.215e-02 | -4.41 | negative regulation of reproductive process | biological process | GO:2000242 | 73 | 31 | 18204 | 5365 |
IGF1,NPPC,BCL2L1,PRDX4,PTGDS,SEMG2,ACVR1C,IL1A,WDR77,OVOL1,WEE2,HPGDS,CALR,MAEL,NPR2,MIR16-1,TIMP1,DUSP1,GJA1,PAEP,CDKN1B,OVGP1,RGN,RAD1,UBE2B,KIT,NKX3-1,SPINK13,EAF2,SOD1,STK11 |
| 1.217e-02 | -4.41 | YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta) | protein interactions | 10971 | 1076 | 335 | 19454 | 5460 |
COPS4,ENKD1,TNF,G3BP1,TRIM37,RASGRP3,TESK2,GPSM3,UCP2,HNRNPA2B1,SNRPE,EZH2,NME1,CHMP4C,WDR37,TPD52,RAF1,CSNK1E,PRKCQ,SRSF10,EGLN3,STK3,INA,CCAR2,RPL7,SNX2,GJA1,KRT8,RPLP2,PHB1,HAX1,CDKN1B,RASSF8,BCL2L1,CAMSAP2,SKIC8,TRAF6,HNRNPA1,PRDX1,ATG9A,CDSN,RNF11,GPC1,CRY1,HADHA,TERT,PSMA3,RTKN,VAPB,ATAT1,CDKN1A,SUPT4H1,WDR77,MAPKAPK5,NDE1,MTX2,MAT2B,RPL19,TMCC1,TUBB,REEP4,ACTB,TAB1,RMDN3,SNRPD1,BAD,HSP90AA1,PFDN2,BAX,ARHGAP19,LMNB1,WDR20,BRCA1,YWHAZ,PDE4B,PRPF31,MAP3K21,MCM3,CUL3,F2,CUL2,CTNND1,RNF20,RNF115,PC,IGF1R,TRAPPC1,PPP1R12A,GARRE1,ADORA3,SERPINA1,UAP1,ACTR2,DDX39A,EEF1A1,ING1,SOCS3,RPL15,UBE2V1,FBP1,YTHDF2,MDM2,ZBTB2,G6PD,KCTD15,PRNP,TFE3,ACTA2,EIF4E2,SSX2IP,FAM53B,FGR,ARL2BP,TIAM1,HDAC6,NFKB1,PFKFB2,FBXW7,PIK3R2,USP8,MIS12,RPA3,SOD1,DVL2,PRPF4,MYH2,RPLP0,CDR2,AGAP1,WTAP,LMNA,PAK5,GRM2,METTL14,MAP3K12,SIPA1L1,SYNRG,CDK7,ATG16L1,SPR,MYL12B,SH3BP4,VIRMA,LDHA,COPE,ZBTB17,GSK3A,STOX2,ALB,CCNF,GAB1,OPTN,STUB1,ENO1,EIF4A3,NCKIPSD,CDC73,IVNS1ABP,SH3BP5L,ATP5F1A,RACGAP1,AR,CSK,CCAR1,CBLL1,PAK6,PTPN4,HNRNPF,H1-6,KRAS,RUVBL2,EFNB1,RTCB,MOB3C,TUBB4B,CRTC2,H1-3,TUBA1A,EEF2,ERRFI1,MIEF1,HSP90AB1,AFTPH,RPS10,CDK17,HNRNPL,TCP1,SUMO2,DYNC1I2,SRSF1,DDX1,SMAD9,CBL,UBFD1,HSPB1,YWHAB,MAGOH,ARL14EP,SLC8A1,AGR2,YWHAH,YWHAG,PPFIBP1,STK4,CTNNB1,TBC1D5,DDRGK1,IFI16,WWP2,UFL1,STAU1,ADRB2,HSPA8,HDAC5,YAF2,ARRDC3,LCA5,MACIR,BMPR1A,CNKSR3,SPECC1L,EIF4B,KLC2,TPD52L1,CSNK1A1,PIH1D1,ADSS2,MAP2K1,PPT1,USP6NL,PPP5C,DES,ESR2,NCKAP1,ATP5F1B,MATR3,REEP3,PRMT5,RRAS2,FAM83B,LMBR1L,DLST,H1-1,CKB,RPS6KA4,BTF3,PSMD1,BAG3,TBC1D1,MYC,SFN,LDHB,RUSC2,HNRNPC,MEPCE,SRSF12,NEDD8,CSE1L,HNRNPK,CLPB,DHX9,TAB2,RNF8,TBC1D4,GNAI3,ZNRF1,TFCP2,DISC1,NHERF1,H2AX,KIF1C,KMT5B,TMPO,CDC5L,ARL6IP5,PLG,ACSL4,SSBP1,CDR2L,RPL10A,MAP4,H2AC4,CSNK2A1,API5,EDC3,GAPDH,MTMR12,HDAC3,FAM53C,PGK1,BAP1,HEXIM1,UBE2M,PRKCA,ACACA,HECTD1,RPA2,WWP1,BORCS5,HBB,CFTR,CAPN1,SMURF1,NMI,TFEB,DYRK1A,KCTD9,DAPK1,MAP3K3,DAPK3,PRKCE,ADRM1,CALML5,PPP2R5E,CCSER2,RPS3,NECTIN2,PDCD4,DTL,ZBTB38,UBE2H,CALU,UNC79,RBM7,SPOP,NIF3L1,ARL6IP6,ARHGAP21,PRKACB,CFL1,SLC25A1,TRIM32,TNFAIP3,RGL2,KCNQ5 |
| 1.220e-02 | -4.41 | skin-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-Merkel_cell_carcinoma | 20 | 11 | 16828 | 4835 |
NF2,AKT1,JAK2,CTNNB1,KIT,TP53,PTEN,PIK3CA,TERT,KRAS,HRAS |
| 1.220e-02 | -4.41 | MALT_lymphoma | COSMIC cancer mutations | MALT_lymphoma | 20 | 11 | 16828 | 4835 |
NOTCH2,IDH1,JAK2,TP53,KRAS,HRAS,CALR,EZH2,MYD88,TNFAIP3,CD79B |
| 1.220e-02 | -4.41 | fibroma-thecoma-fibrothecoma | COSMIC cancer mutations | fibroma-thecoma-fibrothecoma | 20 | 11 | 16828 | 4835 |
DICER1,PIK3CA,STK11,IDH2,JAK2,IDH1,BRCA1,TP53,HRAS,KRAS,CTNNB1 |
| 1.220e-02 | -4.41 | ovary-sex_cord-stromal_tumour-fibroma-thecoma-fibrothecoma | COSMIC cancer mutations | ovary-sex_cord-stromal_tumour-fibroma-thecoma-fibrothecoma | 20 | 11 | 16828 | 4835 |
KRAS,HRAS,IDH1,STK11,CTNNB1,TP53,BRCA1,JAK2,IDH2,PIK3CA,DICER1 |
| 1.220e-02 | -4.41 | bone-skull-chordoma | COSMIC cancer mutations | bone-skull-chordoma | 20 | 11 | 16828 | 4835 |
KRAS,HRAS,IDH1,PIK3CA,SMARCB1,PTEN,TP53,CTNNB1,KIT,IDH2,JAK2 |
| 1.220e-02 | -4.41 | central_nervous_system-brain-glioma-oligodendroglioma | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma | 20 | 11 | 16828 | 4835 |
IDH1,PTEN,SMARCB1,MET,KIT,CTNNB1,TP53,CDKN2C,NF2,NOTCH2,IDH2 |
| 1.222e-02 | -4.40 | ERBIN (erbb2 interacting protein) | protein interactions | 55914 | 241 | 84 | 19454 | 5460 |
CTNNA1,DLG4,GSK3A,LRRC1,RHOJ,ESR2,LMO2,MYC,CSK,SFN,CUL3,PKP4,RAB11A,PPP1CC,DNAJC5,NR2E1,ARHGAP19,CTSK,RHOB,YWHAZ,SMAD2,HSP90AA1,NTRK3,EPHA2,HOXC4,RPA3,DDX39B,RHOU,BANF1,CCDC106,RAB5A,HSCB,MEF2A,STX7,SLC5A6,CLDN4,ATG16L1,RND2,CDC42,CFTR,SLC6A12,RPA2,WWP1,RNF7,ARL15,SHOC2,SMAD3,HRAS,RAB35,GJA1,RAC2,ARF6,HNRNPL,MPP1,RHOH,STX6,EGLN3,KLF9,CAV1,YWHAH,XPO1,YWHAG,CTNNB1,SMAD4,RHOG,CBL,MED4,YWHAB,MAP4,STYK1,ZYX,ATP2B4,PICK1,NTRK2,EPHA4,KRAS,CTNND1,FLOT1,RAF1,ZNF581,SMAD1,ADAMTS1,NUPR1,CASK |
| 1.222e-02 | -4.40 | USP53 (ubiquitin specific peptidase 53) | protein interactions | 54532 | 137 | 51 | 19454 | 5460 |
PC,MSH6,PCGF6,TRAF2,IMP3,CRKL,CHAMP1,EZH2,DDX42,KDELR1,KRT8,HP1BP3,FBXO31,HRAS,PHB1,HNRNPL,TCP1,YWHAG,HNRNPA1,YWHAH,CTNNB1,BAZ1B,RAB3D,AHSA1,RPL23,TMOD2,CSTA,DDX46,HELLS,CREG2,XRCC5,PYGB,AZGP1,NOTCH2,SLC25A3,ACACA,GTF2F2,PSMA6,EIF2AK2,NECTIN2,IREB2,RPL26,PRPF31,MCM4,TUFM,SFN,COP1,ALKBH5,YAE1,FTSJ3,BICD2 |
| 1.222e-02 | -4.40 | AHCTF1 (AT-hook containing transcription factor 1) | protein interactions | 25909 | 137 | 51 | 19454 | 5460 |
STK16,FURIN,EZH2,CBX3,CHMP4C,FAF2,MGARP,NUP37,RAF1,TP53,H3C1,TNFSF8,NUP107,KRAS,SNIP1,S100B,TUBG1,LAMP3,HMGA1,MOV10,ATG9A,IFI16,SLC25A46,RAMP3,NUP35,DNAJC1,FMOD,EED,KRT8,AIFM1,PTPN1,VAPB,RPA2,LMNA,KLRD1,ELOF1,NUP50,DERL1,RPA3,SIRT7,RIT1,LMNB1,PPP1CC,MYC,CUL3,ESR2,VIRMA,APEX1,SNRNP40,FGFBP1,LMBR1L |
| 1.222e-02 | -4.40 | DARS2 (aspartyl-tRNA synthetase 2, mitochondrial) | protein interactions | 55157 | 137 | 51 | 19454 | 5460 |
CDIPT,CCNF,OPTN,LMBR1L,MRM2,CUL3,ETFBKMT,MYC,AUH,MTG2,CYB561,AMACR,EXD2,RPA3,LCN1,SQSTM1,SYVN1,UFL1,HSCB,CFTR,MRPL12,PLP2,FEM1A,ACAA2,RPA2,QRSL1,LDHAL6B,PHB1,AIFM1,SSBP1,GATD3,FAHD1,YBEY,MALSU1,KARS1,CBR4,LRRC40,LAMP3,CCL4L1,POR,HSPD1,SLC25A10,COX8A,UNC50,RASL10B,DCP2,KRAS,ABHD10,CMPK1,DNAJC2,PDHA1 |
| 1.222e-02 | -4.40 | NCOA6 (nuclear receptor coactivator 6) | protein interactions | 23054 | 137 | 51 | 19454 | 5460 |
PPARG,MED23,PAX9,PRMT2,FBXW7,CXXC1,CD40,FOS,XRCC5,HCFC2,EP300,ASCC1,SMAD2,CREBBP,SFN,TXNRD2,AR,NR1H2,RORB,NR1I2,IREB2,VIRMA,ESR2,SRC,GTF2A1,GHR,PDE6D,TOP3B,VDR,TP53,SOX2,JUN,EGR2,TUBA1A,SMAD1,SOX9,ASF1A,PAGR1,PAX6,EWSR1,BAG2,NFKB1,DPY30,YWHAH,YWHAG,TOP1,NUP35,SMAD3,RXRG,WDR82,RB1 |
| 1.223e-02 | -4.40 | SETD1A (SET domain containing 1A, histone lysine methyltransferase) | protein interactions | 9739 | 165 | 60 | 19454 | 5460 |
RERE,PRPS1,RUVBL1,KPNA2,KRAS,H3C1,FHL3,BAG2,TRIM21,RUVBL2,POLR2C,MTA2,CBX3,NFKBIL1,EZH2,ELF1,CTDSP2,TP53,TOP3B,LANCL1,SPPL3,WDR82,H2AC4,ZNF207,CSNK2A1,HDAC6,INO80E,DPY30,PRPF19,HSPA5,CXXC1,TRA2B,DDX5,NUP50,EP300,HSPA8,HCFC2,RPA3,SMARCD3,KLF3,RPA2,KLF12,PRMT2,NEK2,VIRMA,ESR2,MAD2L1,RBBP4,BUB3,SYT2,RPL37A,ELK3,CCNF,BRCA1,DCAF4,KANSL3,PYCR1,SFN,CREBBP,MYC |
| 1.224e-02 | -4.40 | VMP1 (vacuole membrane protein 1) | protein interactions | 81671 | 187 | 67 | 19454 | 5460 |
SPTBN1,MTX2,PGRMC1,OTULINL,SIPA1L1,CNPY3,SEC62,LMNA,SAMM50,SSR1,PICALM,TMOD1,PPM1G,SLC39A9,SPECC1L,DERL1,ARPC2,HSCB,STX7,LDHB,RPL39,RACGAP1,PPP1CC,LMNB1,ATG3,PLN,RIT1,CCNF,CYB5R3,DPEP1,CTTN,SEC61B,SLC1A1,BST2,UMPS,RHOJ,APLNR,ESR2,VIRMA,FAF2,LPAR6,STIM1,RPN1,ACTR2,ARPC3,CAPZA2,ALPL,HGS,PALM2AKAP2,TMT1A,KRAS,CAPZA1,RAB18,LAMP2,RAB5C,FAM20C,FAM174A,EDEM1,LAMP3,ATG7,TPM3,ESYT1,CDH13,ACTA2,HSD17B11,RAC2,LYAR |
| 1.224e-02 | -4.40 | teratoma | COSMIC cancer mutations | teratoma | 52 | 23 | 16828 | 4835 |
PPP2R1A,FBXW7,DHX9,IDH2,JAK2,TP53,FAM53B,PSMD6,KIT,CTNNB1,DICER1,DPY30,PTEN,SMARCB1,TERT,CBL,IDH1,HRAS,KRAS,SMAD4,EWSR1,SF3B1,SLC25A24 |
| 1.229e-02 | -4.40 | negative regulation of post-translational protein modification | biological process | GO:1901874 | 93 | 38 | 18204 | 5365 |
VPS28,BAG2,AKT1,CDK5,MINAR1,UBE2B,TSPO,GCLC,HMG20A,BEX3,TRIM21,SQSTM1,RPL23,UFL1,PLAA,RPS7,ISG15,SVBP,MIR101-1,CHP1,SIRT7,TRIM44,IVNS1ABP,MAD2L2,SPOPL,MAD2L1,CAV1,P3H1,PPIA,RPS3,CAMLG,CRTAP,DCUN1D3,CTNNB1,TNFAIP3,FLCN,CRY1,PRKCE |
| 1.230e-02 | -4.40 | Costimulation by the CD28 family | REACTOME pathways | R-HSA-388841 | 69 | 31 | 10285 | 3229 |
PAK2,SRC,CD80,CTLA4,TNFRSF14,GRAP2,PTPN11,CD86,CD274,PDCD1LG2,PPP2R1A,MAP3K14,PIK3R2,CD4,CD3G,PIK3R1,ICOS,PIK3R3,CDC42,PPP2R5A,PPP2CB,PDCD1,AKT2,PPP2R5E,YES1,PIK3CA,CSK,CD247,AKT3,AKT1,CD28 |
| 1.234e-02 | -4.39 | EGR1 (early growth response 1) | protein interactions | 1958 | 56 | 24 | 19454 | 5460 |
FBXW7,IL1B,NAB1,GADD45A,PSMA3,EP300,MTDH,WWP1,TP53,JUN,JUNB,MDM2,PTEN,BRCA1,GADD45B,FOSL2,CRBN,SP1,NAB2,PFDN5,CREBBP,CTNNB1,DNAJC8,CSNK2A1 |
| 1.234e-02 | -4.39 | HDDC3 (HD domain containing 3) | protein interactions | 374659 | 56 | 24 | 19454 | 5460 |
RAB5A,VRK1,PPP1R8,ATP6V1C1,TOP3B,EHD3,CFTR,SLC29A1,GKAP1,MAGEA4,CARD19,CEP57L1,CYB5R3,GDPGP1,ALCAM,SURF6,NMI,CCDC172,CSTF3,TPM3,HMOX2,EXOC5,TOMM40,CCHCR1 |
| 1.234e-02 | -4.39 | H2AC7 (H2A clustered histone 7) | protein interactions | 3013 | 56 | 24 | 19454 | 5460 |
H2AZ2,MAGOH,HNRNPD,DLST,EIF4A3,RPS3,GSK3A,RPL37A,RPL7,VIRMA,ELK4,EEF1A1,SOX2,CHMP4C,RPS23,RPL18,HEXIM1,RPS24,HSD17B10,PRKCB,FBXW7,MEPCE,RPS4X,RPS13 |
| 1.234e-02 | -4.39 | MACROD1 (mono-ADP ribosylhydrolase 1) | protein interactions | 28992 | 56 | 24 | 19454 | 5460 |
KPNA1,EPHA2,AGR2,IKBKB,BAG3,CETN2,CSTF3,HNRNPL,FAHD1,LIG3,PARP2,EIF2AK2,ACACA,HBE1,EXOC3,RPA2,H2AX,PPP2R1A,RIGI,SSRP1,DHX9,HSPA8,XRCC5,RPA3 |
| 1.234e-02 | -4.39 | KLHL24 (kelch like family member 24) | protein interactions | 54800 | 56 | 24 | 19454 | 5460 |
CPLX3,VIRMA,COPS2,FAM219A,LRRC73,CUL3,KLHL9,GALE,COPS5,CHCHD2,RBM3,GRXCR1,ALKBH4,KLHL28,PDIA6,PICK1,TPPP,DTD1,KLHL12,UBE2M,STAMBP,FNDC8,TIRAP,DDX39A |
| 1.234e-02 | -4.39 | SEPTIN3 (septin 3) | protein interactions | 55964 | 56 | 24 | 19454 | 5460 |
CHRM3,DDIT4L,CKS1B,GABARAPL2,MRPL12,MAP1LC3B,PCMTD2,FGFR1,SDCBP,RNF8,SELENOF,WBP2,SEPTIN6,TRIM11,SEPTIN7,HSD17B8,GPM6A,LASP1,CDC42EP4,RSPH1,CREBBP,CBR4,NTAQ1,PCMTD1 |
| 1.236e-02 | -4.39 | prenyltransferase activity | molecular function | GO:0004659 | 17 | 10 | 18094 | 5411 |
GGPS1,PGGT1B,FNTB,NUS1,PTAR1,COX10,RABGGTB,PDSS2,UBIAD1,FDFT1 |
| 1.238e-02 | -4.39 | response to insulin | biological process | GO:0032868 | 221 | 81 | 18204 | 5365 |
SLC2A8,TNFSF10,PIK3CA,ADIPOQ,SLC2A1,YWHAG,ACVR1C,UCP2,PIK3R3,SOS2,RAF1,IL10,HADHA,SESN3,MIR379,CTSK,AANAT,IGF1R,MIR107,BGLAP,GPT,RETN,AKT2,GCLC,KBTBD2,INPP5K,TBC1D4,PTPN1,AKT1,GHR,SRC,ERRFI1,ZBED3,FBP1,PPARA,HRAS,UPRT,INSIG2,LEP,SELENOS,GRB10,INPPL1,VAMP2,PAX6,FOS,EIF4EBP2,EGR1,STAT1,PCSK9,CAV2,ALPL,CRY1,HDAC5,KCNJ8,RAB31,SHC1,GSK3A,SLC22A12,RB1,SRSF4,CITED1,TWIST2,PCK2,CD2AP,XBP1,PIK3R1,GAB1,CPEB1,PIK3R2,RARRES2,TLR2,SESN2,SP1,OPRK1,PPARG,IDE,FOXC2,RAB13,NCOA5,EGR2,HADH |
| 1.238e-02 | -4.39 | regulation of cell adhesion | biological process | GO:0030155 | 807 | 267 | 18204 | 5365 |
IL21,P2RY12,ITGA6,ROCK1,CDSN,PIK3CA,SDC4,CD47,CXCL8,ACTL6B,IFNG,ST6GAL1,STK4,IDO1,PTPN11,FGL2,ST3GAL4,KLF4,CBLL1,LEP,CD40LG,PIK3CG,THY1,MIR939,CDK6,RAC2,IL18,PRDX2,NKAP,ITGAV,ANGPT1,SRC,LAMB2,DAG1,MIRLET7G,B2M,TFE3,VEGFA,FAF1,ADGRG1,YTHDF2,IL23A,LPXN,UBASH3B,NF2,LRFN3,IL7,IL15,C1QTNF1,EPO,AP1AR,LGALS3,SMARCB1,MIR181C,FZD4,MIR503,CXCL13,EPCAM,F11R,PIK3R2,PIK3R1,TNFAIP8L2,IRF1,PRKCQ,GPNMB,JUP,RELL2,GPAM,TESPA1,SELENOK,RPS3,DUSP1,YES1,TFRC,PRKX,VSIR,ADIPOQ,TNF,ACTB,TWSG1,RBPJ,IL10,DUSP22,ROCK2,XCL1,SMAD3,CX3CL1,TESC,S100A10,CXCR4,EMILIN1,POLDIP2,DUSP10,PLG,PYCARD,GFUS,AGER,HMGB1,SYK,CD1D,CORO1C,EPHA2,HFE,BCL6,CXCL12,RAG1,MIR141,FUT9,TESK1,ILK,ARG2,CCL2,DISC1,IL2RA,TNFRSF14,ICOS,PML,FOXC2,CCR2,AIF1,CCL19,SFTPD,DPP4,TENM3,CTLA4,RHOH,PDCD1LG2,CYRIB,DDR1,CXCR3,CHST2,PRKCA,CYP1B1,LDB1,MIR222,TRAF6,NLRP3,CCL25,MIR183,SFRP1,CSK,IL6,FERMT2,CD86,CDC42,GPM6B,CCL5,CASK,IL12B,SLC7A1,MMP14,EPHA4,IL6ST,PRNP,MIR10A,BTN2A2,DAPK3,KLHL25,SMARCE1,FLOT1,PPARA,PELI1,CD83,PLXNC1,PNP,SASH3,ACTL6A,PPP1R12A,LILRB1,FUT1,DHPS,CD274,IL12A,FOXP3,HTR2A,BCL10,HSPD1,CD36,CD28,CD80,CBFB,SWAP70,EFNA5,IFNB1,CAV1,PPP1CB,MAD2L2,RC3H2,WNT10B,ARPC2,CD46,CD81,LILRB4,MIR146A,MIR519D,IFNA2,MIR30B,CD4,MIR21,CD9,IL20RB,SOCS5,RUNX1,EMP2,SMARCD3,CYTH1,MIR31,JAK1,RGCC,IL4,ZBTB16,ATP5F1B,NCK1,MIR9-1,IL2RG,CD209,EP300,IGF1,MIR192,CD164,CALR,MIR675,DUSP3,IL1A,TGFB2,AGR2,CDH13,CCR7,SEMA5A,DUSP26,ITGA2,GREM1,TNFSF18,ADTRP,FAM107A,PPP3CA,PTPN22,SOX2,SPINT2,IL1B,PKP4,NDNF,SPOCK1,AKT1,PRKCE,BAD,LIMS2,JAK2,PTEN,MIR29C,CCL28,PLA2G5,NRP1,ACTN4,MIR125A,TGFBR2,IL2,EFNB1,MIR221,SNAI2,DLG1,CRKL,CCL21,XBP1,NDFIP1,SOX9,TNR |
| 1.238e-02 | -4.39 | negative regulation of transforming growth factor beta receptor signaling pathway | biological process | GO:0030512 | 128 | 50 | 18204 | 5365 |
MIR20A,LDLRAD4,HTRA1,HSPA5,MIR17,SMURF1,MIR373,MIR106A,BRMS1,MIR342,PPARG,MIRLET7B,MIR497,CHST11,FKBP1A,SIN3A,MIR204,CAV2,EID2,LEMD3,SAP30L,MIRLET7G,MIR424,ING2,PBLD,STUB1,FAM89B,TGFB3,SPRY1,MIR98,USP15,PPARA,MIR140,MIR361,SAP30,RBBP7,PEG10,SPRED1,MIR101-1,BRMS1L,TP53,ZNF451,RBBP4,MIR145,MIR302B,SPRED2,MIR490,ING1,MIR142,MIR9-1 |
| 1.239e-02 | -4.39 | central_nervous_system-brain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_I | 41 | 19 | 16828 | 4835 |
PTEN,FGFR1,TERT,PIK3CA,PTPN11,AKT1,PPP2R1A,IDH2,FBXW7,MET,KIT,GNA11,CTNNB1,TP53,GNAQ,IDH1,HRAS,KRAS,KLF4 |
| 1.239e-02 | -4.39 | HSPB2 (heat shock protein family B (small) member 2) | protein interactions | 3316 | 134 | 50 | 19454 | 5460 |
MAX,UBL5,DUSP1,TRAF2,EEF1A1,PGM1,CAPZA2,RPS11,CYP1B1,HAPSTR1,TNF,ETFA,DMPK,PCGF6,ENKD1,HSPB8,GAPDH,SLC2A1,TRAF6,HNRNPD,PPM1K,HSPB1,CLK4,SNX18,KCTD10,CEP19,MAPKAPK5,LMO3,CFTR,CRYAB,ACAA2,DCTN6,HSPB2,B2M,TGFB1I1,EIF4E,CTSD,ATP5F1A,AR,BAG3,MLF2,TXNIP,MDH1,DDIT4,ENO1,UBE2I,TCAP,EIF4A2,CTSB,ACTB |
| 1.243e-02 | -4.39 | TERF2 (telomeric repeat binding factor 2) | protein interactions | 7014 | 325 | 110 | 19454 | 5460 |
H2BC9,PYCR2,SUB1,SDF2L1,MECP2,CSNK2B,GANAB,GTF2A1,HEXIM2,UBE2I,STUB1,PPP1R10,VIRMA,MAGOHB,ARMC6,RASGEF1C,SNX22,SAP30BP,HEXIM1,TFIP11,RPA2,RPRD1B,TOX4,HSP90B1,RNF113A,CCDC106,ORC6,PPM1G,RPA3,UGDH,TEX264,NBN,IDH3A,PML,PIAS1,NME4,HMGB1,EDC3,BRD3,USP15,NAIF1,GTF2A2,LANCL2,H2AC4,SNRNP70,TNKS,ARL4D,SRP14,DKC1,CDK9,RPL35A,KCTD15,PRNP,TOP1,TMSB10,DDX39A,LBR,H2AX,TAF2,CHAMP1,RING1,CLPB,TCOF1,MDC1,PRDX4,GNMT,PTGES3,KPNA2,THRAP3,RNF40,BAG3,RBM15B,PIK3R3,HSP90AA1,RIT1,BRCA1,PRMT5,SF3B4,ESR2,APEX1,ERH,SIAH1,PRDX3,CTBP1,EP300,SNRPA,BMPR1A,XRCC5,G3BP2,FXR2,DDRGK1,HMGA1,RSBN1L,S100A8,RTL6,WIF1,AFAP1L2,LYAR,FOXJ3,HEXA,PTS,SUPT5H,EZH2,S100B,BCKDK,SSRP1,POLDIP3,KRAS,KCTD17,HMGN4 |
| 1.244e-02 | -4.39 | ARPIN (actin related protein 2/3 complex inhibitor) | protein interactions | 348110 | 23 | 12 | 19454 | 5460 |
DNAAF9,TRIM27,HSPA8,RDH12,LMNA,NIF3L1,FEM1A,XPO1,FCGR2A,SOX2,KBTBD4,DDIT4L |
| 1.244e-02 | -4.39 | USP31 (ubiquitin specific peptidase 31) | protein interactions | 57478 | 23 | 12 | 19454 | 5460 |
VIRMA,CAV1,KRAS,DNAJC5,TRAF2,YWHAH,YWHAG,SFN,YWHAB,TRIM36,RHOB,YWHAZ |
| 1.244e-02 | -4.39 | IL10RA (interleukin 10 receptor subunit alpha) | protein interactions | 3587 | 23 | 12 | 19454 | 5460 |
SMCO4,TMUB2,NFKB1,SELENOK,SLC38A7,PLPP6,SLC7A14,HACD1,JAK1,IL10,SLC66A2,RUSF1 |
| 1.244e-02 | -4.39 | MAST4 (microtubule associated serine/threonine kinase family member 4) | protein interactions | 375449 | 23 | 12 | 19454 | 5460 |
GSK3A,OLA1,SMAD1,YWHAG,YWHAH,SFN,YWHAB,TRIM36,MAPRE1,LEMD3,YWHAZ,BICD2 |
| 1.244e-02 | -4.39 | ZNF333 (zinc finger protein 333) | protein interactions | 84449 | 23 | 12 | 19454 | 5460 |
ARL15,RIT1,ASPM,POGK,ZDHHC17,CBX5,KDM1A,SPPL3,SPTAN1,TRIM63,SENP5,DVL2 |
| 1.244e-02 | -4.39 | BTN3A3 (butyrophilin subfamily 3 member A3) | protein interactions | 10384 | 23 | 12 | 19454 | 5460 |
RPN1,TRIM68,OTULINL,TOMM40,SEC62,RAB11B,TMT1A,RAB13,HSD17B11,ODR4,SEC61B,TRIM11 |
| 1.244e-02 | -4.39 | CD2 (CD2 molecule) | protein interactions | 914 | 23 | 12 | 19454 | 5460 |
LYAR,CD4,ITK,CD58,CD247,SP1,MXD1,DNAJC5,CD59,CD2AP,CD2BP2,MYC |
| 1.244e-02 | -4.39 | NBEAL2 (neurobeachin like 2) | protein interactions | 23218 | 23 | 12 | 19454 | 5460 |
CNPY3,TOP3B,RAB11A,VAPB,YWHAZ,CD40,HRAS,EEF1AKMT3,SPPL3,NPTN,SEMA4C,FBXO22 |
| 1.244e-02 | -4.39 | SNX32 (sorting nexin 32) | protein interactions | 254122 | 23 | 12 | 19454 | 5460 |
TSG101,MNS1,GRXCR1,CHMP2A,RIGI,SNX1,SNX2,DDX39A,RNF40,PIK3R1,NRP1,TFIP11 |
| 1.245e-02 | -4.39 | mitotic cell cycle | biological process | GO:0000278 | 593 | 200 | 18204 | 5365 |
PPM1D,NEK2,PRKCA,GJA1,NAE1,NDP,CCNF,EXOC3,EXOC8,PIAS1,AKAP8L,EXOC5,RAB35,CDK4,LSM14A,TUBB,DCTN6,USP16,CDKN1A,NUP62,PML,EXOC2,CRADD,FBXW11,RPL24,RB1,IK,UBXN2B,RANGRF,PPME1,RINT1,TOPBP1,NSFL1C,ACVR1B,RHOU,NUF2,HINFP,BCCIP,POLDIP2,RHOB,SPTBN1,ROCK2,WEE2,FBXO31,NEK9,TMOD3,RAB11A,RPA2,CUL3,CDKN1B,KLHL22,RAN,CHMP5,PPP2R1A,MAPRE1,CHMP4C,RACGAP1,LIPA,NBN,CCNB1,CCNA2,CUL2,MNAT1,RAD21,EFHC1,NDC80,VRK1,EZH2,NDE1,NRDE2,TBCE,HSPA8,CHMP1B,CKS1B,FBXL7,MCM3,EPS8,CDK6,DTL,MDM2,SKA2,TAF10,CCNY,BIRC5,NLE1,PAFAH1B1,MAP1S,TP53,ARF1,LCMT1,CDC23,AZI2,SKA1,KIF3B,TUBG1,ROCK1,CENPW,CACUL1,CHAMP1,MCM4,VPS4A,TADA3,BUB3,ENKD1,TUBB4B,PSMG2,CCND1,BECN1,REEP4,KIF2A,BANF1,MAD2L1,MCPH1,PPP5C,MIS12,NABP1,ANAPC11,PRKCB,CDK5RAP3,TUBA1A,SKA3,PPP3CA,CDC7,H2BW1,NOP53,SNX33,VPS4B,RTF2,GINS3,RPL26,SMC4,REEP3,SNX18,ABCB1,PCNA,SPC24,DCTN3,FGF10,CCND3,CCNI,UBA3,HDAC3,MDC1,DNM2,PLCB1,SEPTIN6,BRCA1,EXOC1,TAF2,MYBL2,CDKN3,ANAPC2,UBE2I,RPS27L,CKS2,ARPP19,UBE2S,RBBP8,PAX6,MAD2L2,CHMP2A,EDNRA,WNT10B,USP8,TNKS,BABAM1,CHMP2B,BAP1,PIM2,NCAPG2,CNTROB,PSRC1,TRIM36,PPP1R12A,PPP2CB,TPD52L1,CDK1,SPRY1,MTA3,BTN2A2,UBE2A,CFL1,MAP4,TENT4A,NAA50,ZNF207,PHF13,KLHDC8B,MCM6,TUBA1B,ID4,IER3,EIF4E,STAMBP,MYC,CHMP1A,CDC20,CETN2,RTKN,FZR1 |
| 1.247e-02 | -4.38 | U2-type catalytic step 2 spliceosome | cellular component | GO:0071007 | 30 | 15 | 19108 | 5553 |
BUD31,SNRPD2,CDC40,SNRPD3,SNRPB,SNRPA1,SNRPD1,RBM22,PRPF19,SNRNP40,SNRPG,SNRPE,CDC5L,CWC15,SNRPB2 |
| 1.248e-02 | -4.38 | STX17 (syntaxin 17) | protein interactions | 55014 | 254 | 88 | 19454 | 5460 |
PTP4A2,JUP,CTDSP1,HBB,USE1,ARHGAP1,SEC22B,CAPN1,VIPR1,TLR2,LCP1,STK11,SERPINB1,CTNNBIP1,VPS39,VAMP5,SRC,RAB14,KLK9,SNX3,GLTP,CALML5,MACROH2A1,SLC1A1,ALB,ACOX1,CCNF,CTNNA1,SERPINA1,CRABP2,MGARP,MAP1LC3B,CMPK1,SNAP29,VPS16,TF,SLC2A1,SMAD4,HP,EDEM1,IL18,PREP,RB1,ALDH1A3,AIFM1,RDH12,CRYAB,VPS18,EHD1,CNPY3,DUSP14,NT5C3A,CDSN,AZGP1,MLH3,HSCB,GDPD3,PITHD1,EYA3,NMRAL1,RAB5A,AKAP1,FAS,HMGCS1,CAPG,NIBAN2,GFUS,GPBAR1,PYCARD,APLNR,LGALS3,TRIM29,GDPGP1,SDR16C5,VPS33A,AQP3,SERPINA3,VAMP8,IMPA2,KRAS,SLC2A8,HAX1,VAMP7,HNRNPL,ODC1,DIPK2A,STX5,PSME2 |
| 1.256e-02 | -4.38 | growth factor receptor binding | molecular function | GO:0070851 | 138 | 54 | 18094 | 5411 |
FRS3,FAM83B,SOCS5,FGF16,PSEN1,VAV2,IL3,IL7,FGF10,NPTN,PYCARD,TOLLIP,SNX2,JAK2,IL21,AGR2,IL12A,IL1RAP,FGF22,GREM1,FGF3,FGF23,IL1A,FLRT3,VEGFC,IL5,FGF7,CSF2,FGF1,IL1B,IL6ST,RNF41,IL6,RNF126,TLR5,IL4,HBEGF,SNX1,PLSCR1,MYD88,FLRT2,IL10,IL2,IL12B,NHERF1,IRAK4,SHC1,TLR9,VEGFA,SDCBP,FGF17,NCSTN,ARF4,GRAP |
| 1.260e-02 | -4.37 | Keratan sulfate/keratin metabolism | REACTOME pathways | R-HSA-1638074 | 33 | 17 | 10285 | 3229 |
LUM,B4GAT1,B3GNT2,B4GALT1,OGN,FMOD,ST3GAL4,PRELP,HEXA,B4GALT6,B4GALT4,ST3GAL2,ST3GAL1,CHST2,B4GALT3,CHST1,HEXB |
| 1.266e-02 | -4.37 | ITGAV (integrin subunit alpha V) | protein interactions | 3685 | 159 | 58 | 19454 | 5460 |
GGH,ST3GAL1,ILK,MCAT,EPHA2,RHOB,TAFAZZIN,PLP1,VDAC2,VIRMA,RHOJ,CD47,STAT1,PTPRZ1,ST7,CFTR,CDC42,TMEM106A,OTULINL,RND2,CCN3,FUT8,MET,MMP14,EP300,SYVN1,TMEM106B,RHOU,AZGP1,ITGAV,CLEC12B,ST8SIA4,FBXW7,PTN,CXCL12,CALR,LY6G5C,CBL,SHC1,RHOG,SPP1,THY1,RAC2,CAV1,RHOH,B3GNT2,RAF1,PLD3,NCR3,ITGB5,ITGB8,RND3,SFTPC,IGF1R,PSMD12,VDAC1,L1CAM,LCN9 |
| 1.266e-02 | -4.37 | NAGK (N-acetylglucosamine kinase) | protein interactions | 55577 | 159 | 58 | 19454 | 5460 |
SETD5,PRPF19,PPIL4,AGR2,AGPAT1,USP15,UPK1A,SMAD9,FBXO32,TES,WDR82,NRSN1,PRNP,NUP35,GNPNAT1,DDX39A,SOX2,RNF181,STK16,CCR1,GRAP2,CDKN2C,RBM3,HSPD1,PIK3CG,XPNPEP1,DYNC1I1,DCP2,RNF115,RIGI,PRELP,RAB11A,SPRED1,MCM3,NTAQ1,PIGA,CHORDC1,SORD,SMAD2,CCNF,SYNE4,TXN,GPX1,LDHA,SRPK2,GNAI2,BCCIP,LNX2,SPMIP6,STX17,LDHAL6B,LMNA,SDCBP,DVL2,RPA3,RAMAC,HNRNPH2,LSM8 |
| 1.270e-02 | -4.37 | STK11 (serine/threonine kinase 11) | protein interactions | 6794 | 309 | 105 | 19454 | 5460 |
STRADB,RIGI,TNKS2,ERLEC1,JCHAIN,PIK3CA,SMAD1,H2AX,MAP2K3,TP53,PHF23,CDK4,BPIFA2,FBP1,MDM2,GRM1,NAT2,FZR1,TNKS,CDK6,MAP2K6,HRAS,SDHB,TDRD7,BECN1,COPS5,CSNK2A1,NF2,CYP17A1,DVL2,BAP1,MET,RNF146,STX17,FBP2,RPRD1B,IGFBP3,KDELR2,MPV17,ADIPOR1,CTSB,GNPDA1,PTEN,MOB4,PRKRA,CAB39,STUB1,MAPRE1,EPHA2,SERPINB1,YPEL5,STK11,PIP4K2C,STK24,CFL2,AKT1,COPS4,ANP32B,TRMO,RPAP3,CDKN2C,GTPBP1,PLD3,PRKAG1,TUBA1A,SUPT5H,HSP90AB1,COPS7B,BRD9,COPS2,TSG101,TYMS,PPP2CB,WDR6,LYZ,FKBP4,DNTTIP1,ATG7,YWHAG,INO80E,BABAM1,ATG9A,TERT,ARG2,SNRK,CSNK1A1,MAP2K1,AGGF1,FBXO42,FBXO22,AP2M1,VPS72,ZNF189,FBXL14,GTPBP2,HSP90AA1,FBXW11,LAMTOR1,RIOK2,ATG101,PKP4,CUL2,COPS7A,NDUFB6,MYC |
| 1.271e-02 | -4.37 | FOXRED1 (FAD dependent oxidoreductase domain containing 1) | protein interactions | 55572 | 59 | 25 | 19454 | 5460 |
RUNX1,PMPCA,CLPX,AUH,NDUFB10,MOV10,RC3H2,SMAD4,HDHD5,ESR2,VIRMA,TIMM8A,TIMM13,TOMM22,NDUFA5,PDHA1,NDUFS3,HSPA8,NDUFA4,HSPD1,IMMP2L,TOMM20,HSPE1,UFL1,CHCHD2 |
| 1.271e-02 | -4.37 | TBC1D7 (TBC1 domain family member 7) | protein interactions | 51256 | 59 | 25 | 19454 | 5460 |
PIH1D1,SH3GLB2,MMADHC,GABARAPL1,TRIM62,RRAGA,LNX2,LDOC1,DNAAF10,SSNA1,RUVBL2,ELOF1,PICK1,YWHAB,FBXW11,YWHAZ,BECN1,LAMTOR1,YWHAH,YWHAG,AKT1,ATG9A,DYRK1A,MAP1LC3A,CCNF |
| 1.272e-02 | -4.36 | Ribosomal_eL30-like_sf | interpro domains | IPR029064 | 15 | 9 | 18521 | 5414 |
SECISBP2L,RPL7A,ETF1,NHP2,GADD45A,RPS12,GADD45G,GADD45B,PELO |
| 1.272e-02 | -4.36 | cutaneous_T_cell_lymphoma | COSMIC cancer mutations | cutaneous_T_cell_lymphoma | 33 | 16 | 16828 | 4835 |
PTEN,FGFR1,PIK3CA,JAK2,AKT1,IDH2,MET,KIT,RB1,CTNNB1,TP53,SRC,STK11,IDH1,HRAS,KRAS |
| 1.272e-02 | -4.36 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | 33 | 16 | 16828 | 4835 |
PTEN,PIK3CA,FGFR1,IDH2,AKT1,JAK2,TP53,CTNNB1,RB1,KIT,MET,SRC,STK11,IDH1,KRAS,HRAS |
| 1.272e-02 | -4.36 | ATF7IP (activating transcription factor 7 interacting protein) | protein interactions | 55729 | 128 | 48 | 19454 | 5460 |
SAR1B,EWSR1,DISC1,CBX3,POLR2C,POLR2G,POLR2D,STBD1,GTF2E2,SUMO2,RPL8,DNM2,ARL14EP,SMAD4,TNNC2,MED4,ERCC3,MTRF1,SUV39H1,GTF2E1,HMGB1,PML,ZBTB6,RPA3,YAF2,HSPB2,GTF2IRD1,KLF3,RPA2,KRT7,DMTF1,SPTBN1,KLF12,ACTB,VIRMA,ESR2,MAD2L1,ZNF174,CREB1,UBE2I,GTF2F1,ZMYM2,PRSS8,TADA3,H1-1,SP1,HNF1B,CREBBP |
| 1.272e-02 | -4.36 | HSF1 activation | REACTOME pathways | R-HSA-3371511 | 12 | 8 | 10285 | 3229 |
PTGES3,HSBP1,RPA3,EEF1A1,HSP90AB1,HSP90AA1,RPA2,HDAC6 |
| 1.274e-02 | -4.36 | positive regulation of protein localization to plasma membrane | biological process | GO:1903078 | 62 | 27 | 18204 | 5365 |
SQSTM1,DLG1,ATP2C1,CLIP3,AGR2,PRNP,ARF6,RHOG,AKT1,STAC3,EPHA2,ZDHHC8,RANGRF,PIK3R1,KCNJ11,PRKCE,RAMP3,CNPY4,DPP10,IFNG,RER1,TNF,MIR223,PGRMC1,LGALS3,ATP2B4,SPTBN1 |
| 1.281e-02 | -4.36 | Mitotic Spindle Checkpoint | REACTOME pathways | R-HSA-69618 | 21 | 12 | 10285 | 3229 |
ANAPC2,CDC20,ANAPC15,CDC23,CDC16,UBE2D1,ANAPC4,MAD2L1,ANAPC11,CDC26,BUB3,ANAPC16 |
| 1.282e-02 | -4.36 | CDIN1 (CDAN1 interacting nuclease 1) | protein interactions | 84529 | 31 | 15 | 19454 | 5460 |
ASF1A,ZNF609,RBBP7,DNAJC1,H3C1,APEX1,UBN1,FABP5,HIRA,CALML5,CSTA,RIT1,CDAN1,CUL3,SPRR1B |
| 1.282e-02 | -4.36 | NFAT5 (nuclear factor of activated T cells 5) | protein interactions | 10725 | 31 | 15 | 19454 | 5460 |
RPA2,NFE2L2,TBC1D4,FOXP1,JUN,BTF3,HNRNPL,SPPL3,SHPRH,VIRMA,FOXP4,FOXP2,RIGI,FOS,FOXP3 |
| 1.282e-02 | -4.36 | KLHL23 (kelch like family member 23) | protein interactions | 151230 | 31 | 15 | 19454 | 5460 |
COPS5,NUDCD3,CDKN1A,ACOT8,LMO2,CUL3,HSP90AA1,ANXA7,PLS3,CD226,BNIP3L,DCUN1D1,HNRNPL,HNRNPK,STAU1 |
| 1.282e-02 | -4.36 | Snrnp70 (small nuclear ribonucleoprotein 70 (U1)) | protein interactions | 20637 | 31 | 15 | 19454 | 5460 |
GEMIN8,GEMIN7,CAPN1,CCNB1,APOBEC3B,SNRPB,ZNF668,SNRPD3,TXN,SNRPG,SMN1,CCNF,SNRPD1,SNRPD2,PHAX |
| 1.282e-02 | -4.36 | GOLGA8A (golgin A8 family member A) | protein interactions | 23015 | 31 | 15 | 19454 | 5460 |
LCN1,TWNK,CHRM5,CLU,GCA,TRIM26,SCGB1D1,HSPB1,SERPINA1,ELAVL4,RPL26L1,LYZ,JCHAIN,BRCA1,LACRT |
| 1.282e-02 | -4.36 | ZNF276 (zinc finger protein 276) | protein interactions | 92822 | 31 | 15 | 19454 | 5460 |
TOP3B,FAM161A,NOTCH2,MORF4L1,DHPS,LDHAL6B,GCC1,PICK1,AMIGO1,PPP2R5E,CIB3,AP1M1,SEPHS1,ESR2,SNRPA1 |
| 1.282e-02 | -4.36 | CSF2RB (colony stimulating factor 2 receptor subunit beta) | protein interactions | 1439 | 31 | 15 | 19454 | 5460 |
PRKCB,JAK1,IL3,RIGI,JAK2,CSF2,MAD2L1,STAT1,KIT,CISH,PTPN11,SYK,SHC1,YWHAZ,IKBKB |
| 1.282e-02 | -4.36 | LDB2 (LIM domain binding 2) | protein interactions | 9079 | 31 | 15 | 19454 | 5460 |
DGCR6L,EGLN3,RLIM,PSMB1,CETN3,GRIK1,SDCBP,SSBP3,TSNAX,LMO2,SSBP2,NTAQ1,SSBP4,LMO4,LMO3 |
| 1.282e-02 | -4.36 | Bbs5 (Bardet-Biedl syndrome 5) | protein interactions | 72569 | 31 | 15 | 19454 | 5460 |
MAGOH,RBM7,LARP4B,ESS2,ZMAT3,UTP6,TXNL4A,SUPT5H,POLDIP3,SNRNP48,RUVBL1,LSM5,YTHDF1,CCSER2,NGRN |
| 1.282e-02 | -4.36 | ETV5 (ETS variant transcription factor 5) | protein interactions | 2119 | 31 | 15 | 19454 | 5460 |
GRAP2,COP1,UBE2E3,HDAC11,BRCA1,CYP3A5,CISH,DET1,AR,DHRS7,MOV10,CSK,GRPEL1,EP300,CCR5 |
| 1.283e-02 | -4.36 | TERF2IP (TERF2 interacting protein) | protein interactions | 54386 | 549 | 178 | 19454 | 5460 |
PML,NBN,SNCG,BAP1,PRDX6,RBM22,KDM1A,GTF3C4,RPA2,RPRD1B,SUPT7L,PAFAH1B3,LIG3,PPP2R5E,QSER1,EIF4H,RPP25,PPP1R10,AKT1,SUGP1,PDCD4,ANAPC4,SNIP1,HNRNPK,GNMT,MNAT1,MEPCE,ZMYM3,ZMYM4,ESS2,TMSB10,WBP11,IK,DDX42,CHAMP1,CBX3,PHC1,ARL4D,PPIL4,NPSR1,LANCL2,SMCHD1,NAIF1,TRMT5,TAF9,CDK12,XRCC5,SLU7,RFC4,SNRPA,EYA3,PACSIN3,SAP18,ZC3H14,ZNF362,CTBP1,AKR1A1,GAMT,CMTR1,ZHX3,GTF2F1,ZMYM2,PSMD4,KBTBD6,RABIF,ESR2,APEX1,LRIF1,MYC,CREBBP,KANSL3,RBM27,KIAA1191,MDH1,H1-1,BCL7B,HMGN4,ZNF609,CCAR1,DHX38,RBBP9,SUPT5H,SMNDC1,ZRANB2,RBM5,PRCC,WDR82,RFX5,EED,HNRNPL,XPO1,IKBKB,PPM1G,RPA3,HELLS,CCDC106,HMGB1,NUCKS1,PPP1R2,GTF2I,DGCR8,CHMP2B,PIAS1,SAP30BP,WTAP,NUDT18,TRIM24,PTEN,MAGOHB,ZNF507,ZNF687,TAF5L,DNAJC8,RACGAP1,STK24,GGCX,PEA15,CDC73,PQBP1,CPNE2,ZC3H11A,DNAAF10,TSSC4,MDC1,RIGI,RNF20,MTA3,EXOSC8,PGM1,DDX39A,DMAP1,SRP14,RB1,MYBL2,TOP1,THOC1,CWC15,ZBTB2,CDK9,MPG,KIAA1143,ANKRD49,TOPBP1,CFDP1,RADX,POLA2,SUPT3H,ADNP,MFAP1,VGLL4,VPS72,TRMT6,ZMAT2,MED17,CUL3,RNF40,BRCA1,FAS,RGMA,MT3,ZNF592,DHX16,SSRP1,RAD21,GTF3C3,E2F4,GTF2E2,EZH2,MRTO4,THOC2,HP1BP3,DPY30,BABAM1,IDO1,BCL7C,DDX23,COTL1,MT1X |
| 1.284e-02 | -4.36 | ARF | prosite domains | PS51417 | 34 | 16 | 12186 | 3388 |
ARL4D,RAB33B,ARL6,RAB13,ARL5B,ARF4,ARF1,RAB1A,ARL10,TRIM23,ARL15,SRPRB,ARL11,ARL4A,ARF6,RAB29 |
| 1.284e-02 | -4.36 | BZIP_BASIC | prosite domains | PS00036 | 34 | 16 | 12186 | 3388 |
JUN,CREB1,ATF1,XBP1,CREB3,FOSL2,BACH1,NFE2L1,NFE2L2,ATF4,JUNB,ATF3,FOS,NFIL3,BATF,NFE2 |
| 1.285e-02 | -4.35 | protein homodimerization activity | molecular function | GO:0042803 | 714 | 241 | 18094 | 5411 |
BHLHE40,ACHE,FCER1G,DPP4,TYROBP,S100A11,GADD45A,HMGCS1,TP53I3,CHRNA7,PNPO,SMAD3,SMCHD1,ABCB9,DPY30,TXNRD2,IDH1,RCHY1,VPS4B,GSTA4,TRIM22,MAP3K11,FUT9,FOXP2,KIT,RABL3,TRIM21,TESC,DNPH1,LRP6,TYMS,GGCT,ALDH1A3,TRIM68,MAP3K21,BNIP3L,BMPR1A,HM13,SDS,EXD2,NOG,GPRASP3,KARS1,HSD11B1,G6PD,CRYAB,PDE2A,HSP90AB1,GRPEL1,RRAGA,PGRMC1,CISD1,VEGFA,STK26,PSMD7,TGFB2,ISCU,BAK1,GALE,GSTM4,ERP29,BST2,UGT1A1,DDIT3,PDLIM4,FZD4,GSTM2,PAFAH1B2,PAXX,TXN,IL17F,ABCG2,GCA,ODC1,MKLN1,CDSN,CCL5,TYW5,SNX2,NACC2,CER1,MMUT,CD247,MAD2L1,DROSHA,XCL1,QTRT2,FLRT3,TIMM10,NUDT5,ADD1,ASMT,JUP,PLN,NECTIN2,STK4,DCK,CACYBP,CEACAM5,RNF8,PDCD10,RNF40,GHR,MVD,PML,FIBIN,GLCE,CRYM,PHETA2,ADRB3,ST6GAL1,ZNF174,FGFR1,SYNDIG1,HSD17B1,ATG7,MME,MSTN,TPD52L1,BAX,MMAA,CHMP1A,NDP,DGCR8,TENM3,GOLGA5,ACVR1,SSBP1,HSPB8,MSH6,NAA60,CAMK2G,XPNPEP1,ZBTB38,NUDT16,LDB1,IMPA2,TERT,NR0B1,GSTM3,SRM,CYP2R1,SMAD4,SLC39A13,MGAT4A,MORC2,FOXP3,S100A6,DAPK3,GRPEL2,SLC25A14,IRF3,ADRB2,VAPB,RUVBL2,FXR2,SLC51A,TFRC,HPGDS,SLC25A27,TRIM5,S100B,TPPP,SNX1,STARD3NL,MMACHC,STOM,SHMT1,NPC1L1,PRMT2,FBLN5,PHB2,RAG1,TLR9,ACOX1,F11R,ATF3,CLTRN,JAML,HAND2,SH3GLB1,PAFAH1B3,CAV2,ST3GAL2,SPPL3,IKBKB,IDE,GLIPR2,TMEM266,AOX1,CD4,UCP2,CIB2,ZBTB16,CITED1,AKT1,ACTN4,JCHAIN,PADI2,GID8,PYCARD,IZUMO1,TRIM6,NTRK2,CHMP4C,S100A10,GREM1,B2M,MAPK4,EXT1,KLHL7,CRYL1,TRIM37,ENO1,SP1,ZHX3,DNTTIP1,TRIM8,ADD2,THAP1,MAP3K12,TPD52,TPST1,ADIPOQ,HSPB6,RPE,PRKRA,HSPB1,CGAS,TRIM34,PRPS1,LILRB1,HSP90AA1,GTF2A2,TMIGD1,BANF1,GNPTG,TSG101,BOK,STAT1,STUB1 |
| 1.288e-02 | -4.35 | SLC4A2 (solute carrier family 4 member 2) | protein interactions | 6522 | 125 | 47 | 19454 | 5460 |
P2RY1,RHOG,MOV10,RAB5C,CCR6,FAM241A,ARF6,DNAJC1,CAV1,RAB35,THOC2,HSD17B11,GJA1,STARD3NL,RPN1,SLC4A8,CRELD1,CCDC47,OR4N2,KRAS,RIGI,TMT1A,LPAR2,LAMTOR1,LGALS8,CA2,RAB2A,GPR17,SLC41A3,DNAJC5,LGALS3,RHOJ,APLNR,B4GAT1,APEX1,S1PR4,LMBR1L,REP15,RETREG3,SEC61B,SIGMAR1,SRARP,CDC42,STX7,RHOU,TSPAN15,VIPR1 |
| 1.288e-02 | -4.35 | HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) | protein interactions | 3295 | 156 | 57 | 19454 | 5460 |
PHB2,ADRB2,STAU1,NF2,PIAS1,PXMP2,FOS,RPA3,DLAT,RNF113A,NMRAL1,HSPA8,RPA2,RARS1,CDK7,CFTR,DUSP22,PRDX3,ACTB,APEX1,ESR2,DLST,ANAPC2,RC3H2,BICD2,SPOP,UBE2H,FIS1,CDC73,MYC,RACGAP1,G3BP1,DHX16,IMMP2L,HSPD1,EMC2,IDH1,DHX9,PDHA1,VAMP2,TP53,MSX2,EEF2,CYB5R1,TUBA1A,PHYH,EGLN3,HACD3,CD274,SSBP1,CORO1C,TIAM1,PEX3,HNRNPD,BAK1,KARS1,DDRGK1 |
| 1.292e-02 | -4.35 | KDM4D (lysine demethylase 4D) | protein interactions | 55693 | 42 | 19 | 19454 | 5460 |
HINT1,RPLP1,TRIM21,SNRPD2,RBM5,SF3B6,ROCK1,CCAR1,SNRPA1,GGH,AR,PPP1CC,TP53,RBM17,SF3A1,SF3B5,SMCHD1,IDH2,CIRBP |
| 1.292e-02 | -4.35 | ADI1 (acireductone dioxygenase 1) | protein interactions | 55256 | 42 | 19 | 19454 | 5460 |
HNRNPL,MDC1,DBT,OPTN,TRAPPC10,HSD17B10,PGK1,ARFGAP3,TRAPPC14,TRAPPC2L,GNPDA2,MMP14,ADK,UBE2H,PIH1D1,TRAPPC4,GBE1,GALE,BAG3 |
| 1.292e-02 | -4.35 | BLOC1S5 (biogenesis of lysosomal organelles complex 1 subunit 5) | protein interactions | 63915 | 42 | 19 | 19454 | 5460 |
HSBP1,HUWE1,DCUN1D1,OIP5,BLOC1S2,SQSTM1,BORCS8,TSNAX,BCAS4,PTP4A2,PKNOX1,SNAPIN,XPO1,BLOC1S3,BORCS6,CSNK1E,KXD1,H1-5,SNAP29 |
| 1.292e-02 | -4.35 | PTGS2 (prostaglandin-endoperoxide synthase 2) | protein interactions | 5743 | 42 | 19 | 19454 | 5460 |
CASK,HNRNPD,SUMO1,TP53,SELENOS,MYC,NFKB1,COPS7A,CTNNB1,PSMD1,COPS5,FAF2,ELMO1,CAV1,SRC,DERL1,EP300,PSMC5,PTGER1 |
| 1.292e-02 | -4.35 | SIMC1 (SUMO interacting motifs containing 1) | protein interactions | 375484 | 42 | 19 | 19454 | 5460 |
NPTN,SUMO2,NSMCE3,DYNC1I2,VIRMA,ZNF451,PML,CSNK2B,ZMYM2,YWHAZ,COP1,KBTBD4,CUL3,SUMO1,GPR17,P2RY10,HCST,YWHAG,NPY2R |
| 1.292e-02 | -4.35 | Strn3 (striatin, calmodulin binding protein 3) | protein interactions | 94186 | 42 | 19 | 19454 | 5460 |
PPP2R1A,CCT5,AKR7A2,FGFR1OP2,PDCD10,ARPC3,STK24,CCT2,STK26,MOB4,RRAS2,PPP2CB,CCT8,SIKE1,CCT7,CTTNBP2NL,SLMAP,KPNA2,TCP1 |
| 1.292e-02 | -4.35 | GRIA2 (glutamate ionotropic receptor AMPA type subunit 2) | protein interactions | 2891 | 42 | 19 | 19454 | 5460 |
GPM6A,SPTAN1,PICK1,SQSTM1,NEK9,TRMT6,GRIA1,DLG4,RNF167,PRKCA,HAX1,SDCBP,ECD,GAPDH,AGAP2,TXNL4A,SPTBN1,ATP5PB,RAB11A |
| 1.292e-02 | -4.35 | NFE2L1 (NFE2 like bZIP transcription factor 1) | protein interactions | 4779 | 42 | 19 | 19454 | 5460 |
MYC,RUSC2,CAPN1,ATF4,JUN,CREBZF,MAFG,NFE2L1,TULP3,FBXW11,USP15,PHF12,BRD9,GATAD1,FBXW7,RIGI,APEX1,NFE2,JUNB |
| 1.292e-02 | -4.35 | SMIM5 (small integral membrane protein 5) | protein interactions | 643008 | 42 | 19 | 19454 | 5460 |
GINM1,FUT8,EHHADH,SH3GLB1,TMEM179B,LEMD3,TMX4,EFNB1,ARFIP1,SGTA,BMPR1A,PTPN1,GLCE,LRP10,SLMAP,RIGI,SACM1L,LRRC8A,B4GALT7 |
| 1.292e-02 | -4.35 | ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2) | protein interactions | 477 | 42 | 19 | 19454 | 5460 |
ROGDI,LGR4,TPT1,CUL3,SCLT1,HEXIM1,ATP1A3,ZNRF1,TIAM1,IL2RA,ATP6V1A,MAP1B,RAB1A,VDAC2,FBXO25,CCT7,CAND1,VDAC1,PRNP |
| 1.292e-02 | -4.35 | SPRR1B (small proline rich protein 1B) | protein interactions | 6699 | 42 | 19 | 19454 | 5460 |
CBX3,CDAN1,E2F6,CCR1,TANK,MAX,CFTR,NUDT3,ST7,RPAP2,GABPA,ASF1A,ESR2,SCML2,UBN1,FABP5,HIRA,CALML5,POC1B |
| 1.292e-02 | -4.35 | B3GAT2 (beta-1,3-glucuronyltransferase 2) | protein interactions | 135152 | 18 | 10 | 19454 | 5460 |
FAM20B,TMEM59,CLSTN3,RMND1,HSPA5,NLGN2,SELENON,ABHD12,LRP6,ASIC1 |
| 1.292e-02 | -4.35 | ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains) | protein interactions | 64771 | 18 | 10 | 19454 | 5460 |
PPARG,SMURF1,FBXO25,RPSA,MCOLN1,STK26,BAG2,XPO1,HSPA8,PPARA |
| 1.292e-02 | -4.35 | PXDNL (peroxidasin like) | protein interactions | 137902 | 18 | 10 | 19454 | 5460 |
RHOBTB1,KCTD9,SPPL3,KCTD17,SPTAN1,CUTA,COPS2,KLHL3,CSK,CUL3 |
| 1.292e-02 | -4.35 | MLXIP (MLX interacting protein) | protein interactions | 22877 | 18 | 10 | 19454 | 5460 |
YWHAB,RIT1,YWHAZ,XPO1,YWHAG,YWHAH,H2BC9,ZYX,TOP3B,RAN |
| 1.292e-02 | -4.35 | PTGFR (prostaglandin F receptor) | protein interactions | 5737 | 18 | 10 | 19454 | 5460 |
PTGDS,DNAJC5,YIPF4,PTGER1,PTGER2,PTGFR,NDFIP1,SLC20A2,HSP90B1,RHBDD3 |
| 1.292e-02 | -4.35 | ENOX1 (ecto-NOX disulfide-thiol exchanger 1) | protein interactions | 55068 | 18 | 10 | 19454 | 5460 |
ZMYND19,GORASP2,POP5,RPP25L,EEF1G,ZBTB16,SDCBP,NIF3L1,VIRMA,SRSF4 |
| 1.292e-02 | -4.35 | CYP2E1 (cytochrome P450 family 2 subfamily E member 1) | protein interactions | 1571 | 18 | 10 | 19454 | 5460 |
PTN,POR,RPL13A,FANCG,NMI,CLU,STUB1,DDX39A,CYB5A,MAFG |
| 1.292e-02 | -4.35 | GRK3 (G protein-coupled receptor kinase 3) | protein interactions | 157 | 18 | 10 | 19454 | 5460 |
HNRNPL,ADRB2,SMURF1,HSPB1,CCR4,H1-5,CCR5,CXCR4,MYC,OPRM1 |
| 1.292e-02 | -4.35 | GNG7 (G protein subunit gamma 7) | protein interactions | 2788 | 18 | 10 | 19454 | 5460 |
ACP6,GORASP2,CD81,CENPM,GNB3,GNAI2,GNAI3,GNB1,GNB4,FYTTD1 |
| 1.292e-02 | -4.35 | ARHGDIG (Rho GDP dissociation inhibitor gamma) | protein interactions | 398 | 18 | 10 | 19454 | 5460 |
RHOB,GDI2,VDAC1,RHOH,MED10,RHOG,HSD17B10,PPIB,CDC42,KXD1 |
| 1.292e-02 | -4.35 | AP1S3 (adaptor related protein complex 1 subunit sigma 3) | protein interactions | 130340 | 18 | 10 | 19454 | 5460 |
AP1M1,FTL,AFTPH,AP1AR,PRKAG1,AP2M1,SYNRG,AP1G2,ATG9A,COMT |
| 1.292e-02 | -4.35 | NKIRAS1 (NFKB inhibitor interacting Ras like 1) | protein interactions | 28512 | 18 | 10 | 19454 | 5460 |
LCN9,ACVR1,PAEP,APEX1,HSPD1,BMPR1B,NFKBIA,NFKBIB,NAA30,CBLN4 |
| 1.302e-02 | -4.34 | TAX1BP3 (Tax1 binding protein 3) | protein interactions | 30851 | 62 | 26 | 19454 | 5460 |
KBTBD6,PRNP,TRIM29,TXN,CYTH1,CTNNA1,RBBP8,CDK5RAP3,CTNNB1,PPP1CC,TOMM40,PKP4,CYTH2,PSEN1,CTNND1,STAU1,ATP5IF1,RTKN,TCEA2,ARHGEF6,GIT2,ACAA2,PAK2,CTNNA2,VAMP2,UBL3 |
| 1.302e-02 | -4.34 | ARHGAP29 (Rho GTPase activating protein 29) | protein interactions | 9411 | 62 | 26 | 19454 | 5460 |
SMAD4,RHOB,YWHAZ,XPO1,YWHAG,TRIM54,CACYBP,VIRMA,CPSF1,HRAS,EEF1AKMT3,GSK3A,RTRAF,TUBB4B,FGFR1,EEF1E1,JPH4,CAMK2G,KDM1A,FARSA,TRIM37,MRPS17,RIGI,LIN7C,ATP5IF1,RAP2A |
| 1.302e-02 | -4.34 | PAFAH1B3 (platelet activating factor acetylhydrolase 1b catalytic subunit 3) | protein interactions | 5050 | 62 | 26 | 19454 | 5460 |
IGSF21,ZBTB16,PAFAH1B2,PICK1,ERG28,MED31,DDX39A,EEF1A1,TP53,PAFAH1B1,LRIF1,APEX1,LDHA,PRNP,ZHX1,RTRAF,CCNF,CCDC90B,PAFAH1B3,CRMP1,HNRNPD,NIF3L1,COPS5,GAPDH,LDHB,TLE1 |
| 1.302e-02 | -4.34 | LIME1 (Lck interacting transmembrane adaptor 1) | protein interactions | 54923 | 62 | 26 | 19454 | 5460 |
GOSR2,TOP3B,HPCAL1,DDX39A,MEST,GAD2,TMEM243,EGFL8,HSPA8,FRMD8,NINJ1,STX7,TMBIM6,SEC22C,ARFGAP3,PNPO,NAPA,TRAF3IP3,TRAF7,TMEM74,SNX1,GPX1,AIG1,STX6,TMEM97,IDE |
| 1.303e-02 | -4.34 | OGA (O-GlcNAcase) | protein interactions | 10724 | 122 | 46 | 19454 | 5460 |
TPM3,FKBP4,PPP3CA,FBXO32,SIN3A,TES,MAGED2,SNX1,PPP1R18,CCT7,CEP19,LRRC61,TP53,TOP3B,ISG15,COX8A,HINT1,DHX9,CLPB,HNRNPF,SOCS2,PTPN11,MYC,ST13,MCM3,KANSL3,STN1,UBE2H,HSP90AA1,DLST,LMBR1L,CCNF,CSNK2B,SAP30BP,EMC9,JUP,PSMB7,RPA2,CSNK1A1,ACACA,EIF4B,LGI1,PSEN2,BAP1,RPA3,PITHD1 |
| 1.303e-02 | -4.34 | MERTK (MER proto-oncogene, tyrosine kinase) | protein interactions | 10461 | 122 | 46 | 19454 | 5460 |
RPL26L1,MACROH2A2,ZNF326,LMO4,NTPCR,TOMM22,YTHDF1,CCDC86,PEBP1,BANF1,HSP90AA1,SERPINH1,FTSJ3,FBXW11,CHTOP,RPF2,CBX5,ALB,MACROH2A1,ITGB5,GDI2,BMPR2,YTHDF2,SSRP1,RIGI,SRPRB,NDUFA4,PPAN,SFXN1,AHSA1,YWHAB,HBA1,GLO1,TRA2A,BAZ1B,KARS1,CALR,SAV1,STOML2,LANCL1,EIF2S1,SUMO2,S100A8,SRPRA,MRTO4,UBE2N |
| 1.303e-02 | -4.34 | SGO1 (shugoshin 1) | protein interactions | 151648 | 122 | 46 | 19454 | 5460 |
ELOC,CENPW,MED22,FRA10AC1,PPP2R5A,HNRNPAB,RPL7A,NAA50,DSN1,RPL10A,RB1CC1,PFDN2,DROSHA,WDR20,PPP2R5E,USP46,RPLP1,ZMAT5,PPP2CB,WDCP,CBX5,PRNP,RPL35,RPL7,SPPL3,MLLT6,PPP2R1A,ANAPC13,CENPM,PAFAH1B1,SRFBP1,ZNF574,CBX3,CHAMP1,SKA3,CDK1,MIS12,XRCC5,LRRC8D,IMPACT,CTSC,SNRPG,COPS4,CHMP2B,RPL28,RPS15 |
| 1.303e-02 | -4.34 | positive regulation of neuron projection development | biological process | GO:0010976 | 161 | 61 | 18204 | 5365 |
CX3CL1,TMEM30A,NLGN1,ALKAL1,EP300,MIR133B,ZDHHC15,PAFAH1B1,TIAM1,NCK1,TMEM106B,EHD1,TOX,ITGA6,SCN1B,IGF1R,RAP1A,RGS2,NDNF,PTK7,SERPINI1,ELAVL4,NEGR1,FGFR1,NCKIPSD,ENC1,VLDLR,RETREG3,RIT2,KDM1A,MIR200C,DISC1,EPO,NFE2L2,P3H1,RGMA,ATF1,EZH2,ADNP,FKBP1B,FUT9,SNX3,GPRASP3,MIR222,CNTN1,NPTN,AMIGO1,STK24,DDR1,SHOC2,AP2A1,PTN,CNR1,TENM3,CAMK1,FEZ1,ARF6,STMN2,NTRK3,MIR221,NTRK2 |
| 1.307e-02 | -4.34 | regulation of protein targeting | biological process | GO:1903533 | 79 | 33 | 18204 | 5365 |
CDK5R1,STOM,HRAS,HUWE1,ATP5IF1,FIS1,TOMM7,FBXW7,HAX1,TOMM70,PRNP,CDK5,INPP5K,RHOU,RAC2,AKT2,LMAN1,HTRA2,PDCD5,MIEF1,UBE2D3,PARL,BNIP3L,TCAF2,GSK3A,BAP1,UBE2L3,SLC1A1,HPCA,UBL5,CHP1,SH3GLB1,KCNB1 |
| 1.307e-02 | -4.34 | regulation of glial cell differentiation | biological process | GO:0045685 | 79 | 33 | 18204 | 5365 |
TNFRSF1B,NR2E1,SLC45A3,CDK1,RHEB,TLR2,LDLR,DAG1,F2,NOG,DICER1,CXCR4,IL6ST,PRMT5,GPR37L1,DUSP10,DRD3,EGR2,PTN,ASPA,MECP2,DLX1,IL34,MYRF,EPHA4,MIR181C,PTPRZ1,ID4,IL6,NKX6-2,CTNNB1,MIR142,ZNF365 |
| 1.313e-02 | -4.33 | S100P (S100 calcium binding protein P) | protein interactions | 6286 | 277 | 95 | 19454 | 5460 |
SESTD1,ZNHIT6,VPS72,ATXN1L,APEX2,PSMD4,MATR3,FBXO22,ESR2,ATP6AP2,DSN1,CUL2,PROX1,RNF40,BAG3,OSM,BEX3,EP300,STK26,UFL1,ASRGL1,GH1,IL22,EPO,KLC2,IL3,IGBP1,IL10,INA,CDK17,PNPLA8,CACYBP,CSF2,POGK,PTDSS1,INO80E,FEM1B,CDK5RAP3,IFNB1,TRAF6,AGR2,UQCC2,S100B,KRAS,ENKD1,IL13,RAF1,SPC24,SNAPIN,CCR1,MRPL53,STUB1,RNF187,GABPA,ARHGAP21,RPS17,GMNN,IL15,STK24,RRP7A,PPM1G,HELLS,SNAPC1,MIS12,IL5,FBXO9,INTS6L,FAM161A,PRL,TFIP11,LEP,HAUS2,TCEAL8,KCTD15,SHPRH,ERCC3,FAM133B,GTF2A2,IL21,AGPAT1,NOSIP,MRPL52,MRFAP1,SNAPC3,SNRNP48,RNF20,IL12A,UBL4A,TBK1,KIF1C,ESS2,AZI2,AGER,NEFL,BIRC5 |
| 1.313e-02 | -4.33 | positive regulation of protein transport | biological process | GO:0051222 | 249 | 90 | 18204 | 5365 |
SMAD3,IL1A,TGFB2,CHP1,OSBP,EP300,IGF1,PDCD10,TNF,APBB3,RAB29,HYAL2,CTDSPL2,VPS28,TGFB3,IL1B,GOLPH3L,PFKFB2,OAZ2,PRR5L,NR1H2,SYBU,CHRM1,VAMP2,OR51E2,TSG101,HCLS1,EDEM1,JAK2,BAD,GNA11,SRI,PRKCB,CHRM3,PRKCE,NLGN2,TLR2,BAG3,ANP32B,CD2AP,CD38,CFTR,GHRL,TMEM97,ARF6,C2CD2L,F2,EDEM2,TMEM30A,IFNG,ACSL4,PGRMC1,DYNLL1,MDM2,CDC42,PPIA,OAZ1,IL13,EFCAB7,OAZ3,SRC,DMAP1,CDK1,PPID,PDCD5,TM9SF4,LEP,LRRC8A,SNAP25,PARD6A,VEGFC,TLR4,HSP90AA1,MAVS,SAR1B,ACHE,JUP,PIK3R1,RAN,PCK2,PLCB1,RBM22,PIK3R2,HDAC3,ATP2C1,CD81,PSEN1,CAMK1,SFN,PPARG |
| 1.315e-02 | -4.33 | H3-4 (H3.4 histone, cluster member) | protein interactions | 8290 | 404 | 134 | 19454 | 5460 |
CHAMP1,CBX3,TAF2,TBC1D4,BIRC5,LBR,H2AX,ZMYM4,DYNC1I1,VRK1,BACH1,HNRNPK,PHF1,PSMB10,VWF,SMN1,H2BC14,H2AC25,RING1,TGIF2,H2AC4,KPNA1,TAF9,ORC5,H2AC14,CD81,ZMYND11,SUV39H1,TSPYL4,MDM2,MALSU1,H2AZ1,GATAD1,DYRK2,PRKCA,RAG1,UBA52,CXCL8,GTF3C4,SMYD3,SGF29,KDM1A,MEF2A,MBD3,PPM1G,NBN,BICD2,TADA3,CDC73,TADA1,UBE2H,TAF5L,MORF4L1,H2BC9,NONO,HPF1,DEK,CREB1,EIF4A3,ING2,PSMC5,MACROH2A1,EZH2,SMNDC1,PDHA1,MTA2,TAF10,ANP32A,OTUD6B,DCUN1D3,KIF2A,SAP30,RBBP7,CBX7,ASF1A,TRIM37,PCGF6,HNRNPA2B1,ABCF1,GADD45A,JAK1,SEC11A,KDM2A,MGMT,RPL23,MAGOH,HMGA1,TAF7,CDC26,DPY30,PPIB,HNRNPA1,PGR,POLR3F,HNRNPL,RHOH,LRWD1,SIN3A,EED,CTBP1,ADNP,TCF19,PIH1D1,H1-5,PAFAH1B1,SUPT3H,ELK4,TNFSF10,HSPA8,HDAC5,EP300,NUP50,RBP5,TAFAZZIN,H1-10,HSP90AA1,ICAM1,PHF7,SETD7,H1-1,MYC,CREBBP,HNRNPAB,BTF3,RBBP4,LRIF1,CBX5,TAF11,JAK2,PHF12,RAN,PARP2,PRMT5,PHF21A |
| 1.316e-02 | -4.33 | Regulation of insulin secretion | REACTOME pathways | R-HSA-422356 | 80 | 35 | 10285 | 3229 |
CACNB3,SNAP25,SLC2A1,AHCYL1,STXBP1,GNGT2,GNB3,GNAI2,SLC25A5,STX1A,GNG5,SLC25A4,GNG11,PLCB1,GNAQ,CACNB2,GNA14,GNG10,ARL2BP,GNG13,PLCB2,GNG3,VAMP2,RAP1A,KCNJ11,GNG12,KCNB1,GNG2,GNB4,GNG7,PRKCA,GNB1,PRKACB,CHRM3,GNA11 |
| 1.317e-02 | -4.33 | transcription coregulator activity | molecular function | GO:0003712 | 501 | 173 | 18094 | 5411 |
PQBP1,CRYM,RBFOX2,TRIM15,EZH1,DDX1,MTDH,MED23,TRIM62,IRF4,MED30,EID2,TLE1,JADE1,SMARCE1,DYRK1B,NUPR1,NME2,AIP,EZH2,MIDEAS,NIBAN2,PRKCB,TOB2,UBE3A,SUB1,TADA1,NFKBIB,JUP,PIR,PHB1,RB1,CNOT7,ENY2,RAP2C,CNOT6,EWSR1,MED13L,BCL9,THRAP3,SSBP3,MTA3,DMAP1,BRCA1,FBXL19,SIN3A,RLIM,C1D,RERE,USP16,DYRK1A,VGLL2,KDM1A,MED29,PCBD1,ACTL6A,EID1,YAF2,DDIT3,LDB2,COPS2,NAB2,SAP30,SAP30L,PRMT5,WBP2,SRSF2,BIRC2,CCAR1,HMGA1,MED10,SIAH2,SETD4,CBFB,ACTL6B,NCOA5,UBE2L3,HSBP1,DHX9,CTNNB1,SETD3,TRIM21,BTG1,GMNN,ARL2BP,HMGB1,TRIM22,RIOX2,PFDN5,TRIM8,MED31,BTG2,TGFB1I1,MED22,SUPT7L,SMARCB1,TRIM37,ENO1,CD274,RNF14,NAB1,TRIM27,SAP18,TRIM32,TSG101,BEND6,FHL3,NFKB1,WDR77,PHF12,TAF11,LMO4,CITED1,SS18,LMO3,ZBED1,MED21,HCFC2,EP300,SERTAD2,MED27,ACSS2,LPXN,COPS5,BCL10,RNF20,SUPT3H,RBBP8,ACTN4,NUCKS1,BUD31,PRMT2,TRIM5,DHRS7B,RUVBL2,MED11,RUVBL1,CNOT2,TAF5L,HIRA,SMARCD3,MED9,TADA3,KDM2A,HYAL2,IRF2BP1,ELK1,TRIM24,APEX1,SUFU,MECP2,HDAC3,TRIP4,HR,FOXP3,TAF9,MED4,EID2B,MTA2,ZMYND11,CREBBP,CCND1,SETD5,LMO2,NR0B1,TRIM52,EDF1,SDR16C5,CTBP1,MED17,LDB1,ZNF451,PIAS1 |
| 1.317e-02 | -4.33 | THAP1 (THAP domain containing 1) | protein interactions | 55145 | 119 | 45 | 19454 | 5460 |
MRPL53,POLR2L,UBE2I,HYPK,YES1,NKAP,AKAP17A,CDC5L,RPL22,MORF4L1,ZCCHC10,CDKN2D,NTAQ1,PID1,CSNK2A1,GAS8,TPM3,RIT1,PPIG,SLU7,DVL2,NKAPD1,TCEA2,DCTN3,SREK1IP1,LASP1,TRIM26,FXR2,KRAS,FGF12,PHF1,STRBP,NUP62,SAP30BP,TP53,MRPL11,TTLL10,NDUFAB1,RALYL,THAP1,KLF12,LMO3,ZNF526,FGF10,MFAP1 |
| 1.317e-02 | -4.33 | H2BC18 (H2B clustered histone 18) | protein interactions | 440689 | 119 | 45 | 19454 | 5460 |
MEPCE,H3C1,ABCE1,BAG2,UBE3A,MAP1B,RBM34,H2AX,TMPO,DLGAP4,H2AZ1,FOLR1,BRD3,RPL10A,EMX2,AGR2,H2AC4,CD81,DDRGK1,HMGA1,UFL1,IL1RAP,GID8,HEXIM1,VPS54,ELK4,H1-5,UBA52,FUT8,SH3BP4,VIRMA,CCNF,FAIM,ZNF330,ICAM1,H1-1,MECP2,H2AZ2,PSMD14,BTF3,PRPF31,MYC,RPL7A,IKZF2,KCNQ5 |
| 1.319e-02 | -4.33 | AB_hydrolase_1 | interpro domains | IPR000073 | 30 | 15 | 18521 | 5414 |
SPG21,ABHD10,ABHD16B,ABHD5,PPME1,MEST,LIPA,ABHD12,ABHD14B,ABHD8,ABHD2,ABHD13,EPHX1,ABHD4,ABHD6 |
| 1.322e-02 | -4.33 | BTB-kelch_protein | interpro domains | IPR017096 | 46 | 21 | 18521 | 5414 |
KBTBD6,KLHL25,KLHL26,CCIN,KLHL28,KLHL3,KLHL22,KBTBD3,KLHL15,KLHL9,KBTBD2,KLHL32,KBTBD4,KLHL7,KLHL1,IPP,IVNS1ABP,KLHL24,KLHL23,ENC1,KLHL12 |
| 1.323e-02 | -4.33 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:2001240 | 35 | 17 | 18204 | 5365 |
IL1B,MCL1,CX3CL1,IL1A,AKT1,CTNNA1,TNF,PRDX2,BCL2L1,EYA3,IFI6,STRADB,IL7,TERT,FGF10,CSF2,SNAI2 |
| 1.323e-02 | -4.33 | regulation of synaptic transmission, GABAergic | biological process | GO:0032228 | 35 | 17 | 18204 | 5365 |
NLGN2,ADRA1A,ADORA1,USP46,TACR1,CA2,PLCL1,NLGN1,KRAS,SLC6A1,STXBP1,NPY5R,CNR1,SYN3,OXTR,SLC38A1,PRKCE |
| 1.323e-02 | -4.33 | regulation of presynapse assembly | biological process | GO:1905606 | 35 | 17 | 18204 | 5365 |
LRRTM1,WNT7A,DKK1,NLGN2,SLITRK1,NTNG2,ARF6,CBLN2,SLITRK5,CLSTN3,SLITRK2,CBLN1,LRRC4B,LRFN3,LRRTM3,IL1RAP,GPC4 |
| 1.323e-02 | -4.33 | negative regulation of signal transduction in absence of ligand | biological process | GO:1901099 | 35 | 17 | 18204 | 5365 |
CSF2,FGF10,SNAI2,TERT,IL7,EYA3,IFI6,STRADB,BCL2L1,TNF,PRDX2,CX3CL1,IL1A,AKT1,CTNNA1,MCL1,IL1B |
| 1.323e-02 | -4.33 | signal transduction in absence of ligand | biological process | GO:0038034 | 35 | 17 | 18204 | 5365 |
BAK1,GSK3A,IL2,FGF10,BAX,BAD,ITGAV,BCL2L1,BOK,MCL1,IL1B,BCL2A1,FAS,IL1A,CX3CL1,BAG3,CTNNA1 |
| 1.323e-02 | -4.33 | regulation of presynapse organization | biological process | GO:0099174 | 35 | 17 | 18204 | 5365 |
CBLN2,ARF6,SLITRK5,CLSTN3,CBLN1,SLITRK2,LRFN3,LRRC4B,GPC4,IL1RAP,LRRTM3,LRRTM1,WNT7A,NLGN2,DKK1,SLITRK1,NTNG2 |
| 1.323e-02 | -4.33 | negative regulation of macroautophagy | biological process | GO:0016242 | 35 | 17 | 18204 | 5365 |
TSPO,PIK3CA,PHF23,AKT1,TMEM39A,TP53,BECN1,POLDIP2,SCFD1,HDAC6,SEC22B,FEZ1,USP30,RNF41,NUPR1,MTM1,LYPLA1 |
| 1.323e-02 | -4.32 | STK3 (serine/threonine kinase 3) | protein interactions | 6788 | 175 | 63 | 19454 | 5460 |
GNAI3,RAF1,CSNK1E,GABARAPL1,MAP1LC3B,ERLIN2,HSPE1,MOB3B,PAEP,TFPT,SNIP1,MAP1B,ZC3H7A,YWHAB,IFI16,RASSF4,MAP1S,SAV1,NDUFV2,YWHAH,XPO1,YWHAG,STK4,SUV39H1,INA,CPNE1,KIF3B,MPP1,SLMAP,EGLN3,CACYBP,STK3,MAP1LC3A,RNF128,CDK1,VAPB,ACACA,SPTBN1,MYH1,HSCB,FBXW7,STAU1,MRPL40,GABARAP,MYH2,TAFAZZIN,FBXW11,CCDC174,FGFR1OP2,AKT1,CUL3,NOP16,TAB1,CTTNBP2NL,TRAF1,DDAH2,GNAI2,VIRMA,ZNF189,PHAX,MOB4,CFAP298,PHKB |
| 1.323e-02 | -4.32 | RAMP3 (receptor activity modifying protein 3) | protein interactions | 10268 | 175 | 63 | 19454 | 5460 |
LYPLAL1,CBR4,AGPAT1,SLC20A1,RPL23,PEX3,HDHD5,GLT8D1,C2CD2,DECR2,CD151,RAMP3,EXTL2,B3GNT2,PREB,TMEM126A,TMEM205,AGPAT5,TUBA1A,ALG11,PTRH2,DHRS7B,SLC25A20,GLCE,RUSF1,SLC39A3,SEMA4C,HS2ST1,PSEN1,PYCR2,KDSR,SLC1A3,RHOBTB3,MBLAC2,ATP1A3,GGCX,SLC7A11,FAM210A,SFXN2,GGT7,PRSS8,SLC25A4,LGALS3,TUBB,MGST3,NDUFAF4,PARL,VKORC1L1,ABHD12,FUT8,TMEM219,SLC35F6,TIMM29,NTPCR,SLC35E1,KDELR2,GHITM,CTDSP1,VIPR1,IL1RAP,TMEM209,UQCC3,NT5C3A |
| 1.329e-02 | -4.32 | INAVA (innate immunity activator) | protein interactions | 55765 | 65 | 27 | 19454 | 5460 |
ACTR1A,TUBA1A,FBP1,VAC14,RPS11,RPL18,P3H1,DCTN3,DCTN6,PSME1,RPL28,CYTH2,SKP1,NEDD8,SGF29,FXR2,CALR,TAX1BP3,RPL6,SAV1,FBXW11,CRTAP,CYTH1,TRIM27,TNKS,WDR6,RPL10 |
| 1.329e-02 | -4.32 | COMMD8 (COMM domain containing 8) | protein interactions | 54951 | 65 | 27 | 19454 | 5460 |
NFKB1,CUL3,COMMD5,INSYN1,TFDP2,COMMD9,CCDC22,BOLA1,ATP6V1D,PSPC1,QSER1,COG1,COMMD6,VPS26C,UBB,NUP62,AKR1C1,ACTR1A,COMMD3,STMN2,SCLT1,E2F6,TMX2,CNKSR3,HSPA8,MIA2,COMMD2 |
| 1.329e-02 | -4.32 | ARHGAP26 (Rho GTPase activating protein 26) | protein interactions | 23092 | 65 | 27 | 19454 | 5460 |
SOX2,CDC42,ACTL6A,TOP3B,CPSF4,CSNK1E,TOX4,CDC42EP2,EMG1,OPHN1,ACADS,LSM4,QPCTL,PYCR1,CSK,THOC6,CA2,PTEN,C2CD2,TACO1,SF3B6,PSPC1,VIRMA,SMURF1,MAPRE2,NYAP2,PLG |
| 1.329e-02 | -4.32 | TMEM205 (transmembrane protein 205) | protein interactions | 374882 | 65 | 27 | 19454 | 5460 |
HMOX2,ARL6IP6,TOMM40,TSPAN10,PLN,AGR2,TMEM11,AK2,COMT,VDAC2,ESR2,RAMP3,STX6,PLXNC1,B4GALT3,MGST3,GOSR2,TP53,SLC25A3,SLC25A20,RPA2,NDUFA4,TSPAN15,STX8,RPA3,STX7,CD1B |
| 1.329e-02 | -4.32 | Bag2 (BCL2-associated athanogene 2) | protein interactions | 213539 | 65 | 27 | 19454 | 5460 |
RPS3,WDR6,STUB1,CCNF,POLR2B,HSP90AB1,RPL10,MLF2,COX11,CIRBP,DNAJC7,HSP90AA1,DNAJB6,RPL23,NEK9,HSPA8,DNAJB4,DDX5,CERS2,TRIM26,MRPL41,GRPEL1,TOP3B,TUBA1A,GTF3C4,STOM,KLF4 |
| 1.329e-02 | -4.32 | PHKA2 (phosphorylase kinase regulatory subunit alpha 2) | protein interactions | 5256 | 65 | 27 | 19454 | 5460 |
RAF1,TP53,MAP2K3,TULP3,QRSL1,CHMP1A,PPP1R12A,BAP1,METTL18,UBE3A,ROCK2,VRK1,FGF12,ITGAV,SAP18,TCEANC2,CMSS1,BTF3L4,PHKG1,PHKA1,STK4,SMAD9,DOK4,UBE2S,PHKB,ROCK1,STK3 |
| 1.329e-02 | -4.32 | H3C2 (H3 clustered histone 2) | protein interactions | 8358 | 65 | 27 | 19454 | 5460 |
MCM4,H1-1,MACROH2A1,TRIM24,LIG3,PARP2,H2AZ1,CREB1,CETN2,VIRMA,CBX5,RBBP4,UBR7,H2AX,CRTC2,MACROH2A2,PDHA1,HMCES,BANF1,HIRA,SSRP1,MCM6,PHF1,GINS3,ASF1A,H1-6,RBBP7 |
| 1.329e-02 | -4.32 | ABHD11 (abhydrolase domain containing 11) | protein interactions | 83451 | 65 | 27 | 19454 | 5460 |
DOK6,S100A6,COMT,LDLR,FAHD1,TXNDC12,MDFI,LAMTOR2,MGAT5B,AK2,FAS,CHCHD4,BOLA1,BOLA3,OSTM1,PEBP1,PTRHD1,PRDX6,NME4,GUK1,YTHDF1,GCA,LYPLA1,SPR,DHRS4,PGM1,VAC14 |
| 1.329e-02 | -4.32 | nucleosome binding | molecular function | GO:0031491 | 95 | 39 | 18094 | 5411 |
MTA2,H1-10,SAP30L,MBD3,HMGN4,MLLT6,HIRA,MACROH2A1,H2AC1,H2AC7,HP1BP3,PARP2,HNRNPC,H1-6,H1-5,SMARCE1,H2AZ1,ACTB,CGAS,H2AC4,EZH1,H1-3,H1-1,H2AX,SSRP1,H2AC6,SMARCB1,H2AC25,ZNHIT1,EED,DNTTIP1,SMARCA5,MACROH2A2,H2AC13,H2AJ,H2AB1,ACTL6A,RBBP4,H2AZ2 |
| 1.334e-02 | -4.32 | positive regulation of receptor signaling pathway via JAK-STAT | biological process | GO:0046427 | 43 | 20 | 18204 | 5365 |
LEP,ADIPOR1,GH1,F2,IL6,MIR221,GHR,OCIAD2,CYP1B1,KIT,IL10,IL4,EP300,PRL,IL5,CSH1,JAK2,CRLF3,CCL5,TNF |
| 1.335e-02 | -4.32 | mitochondrial respiratory chain complex IV | cellular component | GO:0005751 | 20 | 11 | 19108 | 5553 |
COX5A,COX8A,COX7B,NDUFA4,COX4I1,UQCRC2,COX6A2,COX7A1,COX6B1,COX4I2,COX6C |
| 1.336e-02 | -4.32 | ELOA (elongin A) | protein interactions | 6924 | 229 | 80 | 19454 | 5460 |
KXD1,IFI16,MDFI,PRPF19,ELOC,DDRGK1,SNRNP70,SKIC8,DDX23,MED21,NAB2,CDK12,CEP57L1,CDR2L,POLR2L,POLR2I,LYAR,CNTROB,SUPT5H,RAP1A,RAF1,CSNK1E,H2AJ,LBH,PSMB9,SOX2,CDK8,CBX3,TMEM14B,POLR2C,POLR2G,POLR2D,RPL31,RUSF1,RPS24,TRIM21,TRIM37,NEDD8,H3C1,SSRP1,CUL3,MYC,CEP70,RNF40,ANAPC15,PIP4K2C,BRCA1,RHOB,YWHAZ,UBE2H,PEA15,CDC73,ZNF330,DLST,EZH1,CTTN,TACO1,STUB1,POLR2F,INTS12,PRMT5,RPGRIP1L,SPCS1,TRIM54,JAKMIP2,SSH3,VIRMA,TCEAL7,APEX1,POLR2B,PPP1R10,EHHADH,CDK7,LMNA,RPA2,PRPF4,SPECC1L,RPA3,PSENEN,COIL |
| 1.336e-02 | -4.32 | USP2 (ubiquitin specific peptidase 2) | protein interactions | 9099 | 229 | 80 | 19454 | 5460 |
MAVS,CRY1,TRIM5,SF3B1,NBN,JAKMIP1,PML,BAP1,VPS28,DDI1,RNF11,FBXW7,OIP5,CCND1,BEND5,LNX2,PRR5L,MYLIP,SPDYE4,TFIP11,LMNA,TRIM27,UBE2S,MID1IP1,PNMA1,OPTN,TRAF1,TAX1BP1,TRIM46,STAT1,TRIM54,AR,CEP70,CCDC85B,GPRASP3,EXOC5,ATP5F1A,PIK3R3,MYC,SMAD2,TRIM23,BRCA1,BICD2,TRIM21,PCNA,PICK1,RAB1A,PCGF6,MNAT1,DUSP21,S100A10,TRIM63,RBCK1,TGFBR2,ZBED1,EXOSC8,TRAF2,E2F4,TBK1,RNF126,NEFL,DISC1,SKA3,LDLR,HOMER3,SERPINC1,SMAD3,MDM2,RNF144B,TRIM35,TRIM34,CTNNB1,TRIM8,MOV10,ORC5,USP15,NAB2,H2AC4,TRAF6,SLC2A1 |
| 1.342e-02 | -4.31 | human chr15q25.1 | chromosome location | human chr15q25.1 | 45 | 17 | 26134 | 5823 |
ZFAND6,IREB2,MINAR1,STARD5,IDH3A,TLNRD1,PSMA4,BCL2A1,MTHFS,CFAP161,CIB2,MORF4L1,SKIC8,FAH,TMED3,MIR549A,MIR184 |
| 1.344e-02 | -4.31 | LRWD1 (leucine rich repeats and WD repeat domain containing 1) | protein interactions | 222229 | 113 | 43 | 19454 | 5460 |
CCNA2,FOXS1,CDK1,LMNA,RPA2,FEM1A,RPA3,ORC6,XRCC5,NLE1,IRF3,THBS3,STAU1,MYC,RUNX1,GGH,GMNN,STN1,PRMT5,TRIM29,TAX1BP1,ESR2,TOP3B,TP53,CARTPT,CBX3,EZH2,RNF126,NUPR1,ALKBH4,BAG2,H3C1,ORC5,TUBG1,DDX23,H2AC4,DNAJC7,BRD3,FBXO32,PRR3,ADD1,LRWD1,CDC5L |
| 1.344e-02 | -4.31 | NCOA5 (nuclear receptor coactivator 5) | protein interactions | 57727 | 113 | 43 | 19454 | 5460 |
HNRNPC,MYC,MOV10,GORASP2,TRA2A,SNRPB,PPP1CC,ANAPC15,HNRNPA1,ATG101,NTAQ1,ATOSB,DLST,SSU72,AIFM1,SNRNP40,TOP1,EIF2S1,PAIP1,MATR3,NUP35,TNPO3,ZBTB2,SUPT5H,E2F4,PABPC5,UBL5,TBK1,PPP1CB,ZNF326,LARP4B,NUDT12,TMEM14B,NCOA5,EIF4B,SNRPA,SRSF7,GALC,RAB30,TWNK,PICK1,B9D2,SSRP1 |
| 1.344e-02 | -4.31 | LRP10 (LDL receptor related protein 10) | protein interactions | 26020 | 113 | 43 | 19454 | 5460 |
DLK2,IFNAR1,GPR17,PLEKHO1,MFSD14B,TMEM179B,SLC20A1,CALHM5,RHOG,RHOB,ADAM21,TMEM74,NRSN1,SPINT2,TMEM237,MGST3,MARCHF4,RHOJ,HTRA1,MANSC1,RND2,TMEM59,CDC42,IFNGR1,TMEM231,PDCD1LG2,CHRM3,IL20RB,TSPAN3,LMNA,CTLA4,WWP1,MRPS18B,LPAR2,TSPAN17,OR1M1,TMEM243,RUSF1,CXCR4,RHOU,RIGI,LITAF,TGFBR2 |
| 1.344e-02 | -4.31 | LAT (linker for activation of T cells) | protein interactions | 27040 | 113 | 43 | 19454 | 5460 |
LMNA,SPRY1,GRAP2,MS4A7,SYK,KCTD17,APH1A,GJB1,MRPS18B,BSCL2,PIK3CG,TRAF6,TM4SF18,CRBN,SLPI,FCGR1A,CBL,HSP90AA1,MFSD14B,CD247,OPRM1,CDIP1,CREB3,PIK3R1,NDUFAF2,FCGR2A,GRAP,LHFPL1,TMEM237,LCP2,TMEM45B,SSMEM1,CAMLG,PTPN1,ITK,SGTA,ALB,CD4,CD3G,SLC19A3,MFSD5,CYBC1,SYT2 |
| 1.344e-02 | -4.31 | TUT7 (terminal uridylyl transferase 7) | protein interactions | 79670 | 113 | 43 | 19454 | 5460 |
IGF2BP1,RPL10A,DCAF4,ZNF668,TOMM40,MOV10,MYC,RPL6,CCNB1,MIRLET7D,VIRMA,SURF6,RPS16,RPS10,SPPL3,MIRLET7G,RPL7L1,RPL13A,PRKRA,RMDN3,MIRLET7B,MIR25,RPS3,SYNCRIP,LMBR1L,RPL26L1,APOBEC3C,SOX2,TIMM13,RPL15,RAF1,ATG16L1,ZDHHC17,MIRLET7C,RPL28,RPS13,DGCR8,RPL4,RPL3,MIRLET7I,RPL31,SIRT7,FGF3 |
| 1.344e-02 | -4.31 | PTTG1 (PTTG1 regulator of sister chromatid separation, securin) | protein interactions | 9232 | 113 | 43 | 19454 | 5460 |
CDC20,SMURF1,TRIM15,HYPK,FZR1,RPS10,ANAPC2,CSNK2B,RPL32,UBE2N,SYNCRIP,PTTG1,ANAPC4,RPL24,FAS,KPNA6,XPO1,CDC37L1,HNRNPAB,PPP2R5A,CEP85,PIK3R1,CREBBP,MRPL22,RPL28,NF2,ANAPC11,TRA2B,B2M,PSMA3,SRSF7,LUC7L3,ZCCHC17,CDK1,COX6C,GINS4,SKA3,PIK3CA,CFTR,PPP2R1A,TP53,LIAS,RPS14 |
| 1.346e-02 | -4.31 | lipoprotein catabolic process | biological process | GO:0042159 | 15 | 9 | 18204 | 5365 |
LYPLA2,ABHD17A,LIPA,PPT1,LYPLAL1,LYPLA1,CTSD,LDLR,ABHD10 |
| 1.346e-02 | -4.31 | negative regulation of protein import into nucleus | biological process | GO:0042308 | 15 | 9 | 18204 | 5365 |
SUFU,ANGPT1,PKIA,CHP1,SUMO1,UFM1,CD36,RAB23,PKIG |
| 1.346e-02 | -4.31 | pyrimidine nucleoside monophosphate biosynthetic process | biological process | GO:0009130 | 15 | 9 | 18204 | 5365 |
UCKL1,DCK,UCK1,TYMS,UPRT,UCK2,CMPK1,UMPS,SHMT1 |
| 1.346e-02 | -4.31 | removal of superoxide radicals | biological process | GO:0019430 | 15 | 9 | 18204 | 5365 |
CYGB,NQO1,PRDX1,PRDX2,CCS,SOD1,MT3,SOD2,SOD3 |
| 1.346e-02 | -4.31 | gamma-aminobutyric acid transport | biological process | GO:0015812 | 15 | 9 | 18204 | 5365 |
CACNB4,SLC6A1,SLC6A8,SLC32A1,SLC7A14,NHERF1,SLC6A6,SLC6A12,SLC6A11 |
| 1.346e-02 | -4.31 | post-translational protein targeting to endoplasmic reticulum membrane | biological process | GO:0006620 | 15 | 9 | 18204 | 5365 |
SEC61A1,SEC61A2,SEC62,HSPA5,SEC63,SEC61G,UBL4A,SGTA,SEC61B |
| 1.346e-02 | -4.31 | RNA capping | biological process | GO:0036260 | 15 | 9 | 18204 | 5365 |
CMTR2,SNRPG,SNRPD3,CMTR1,SNRPB,SNRPD2,SNRPD1,SNRPE,RAMAC |
| 1.346e-02 | -4.31 | positive regulation of telomerase RNA localization to Cajal body | biological process | GO:1904874 | 15 | 9 | 18204 | 5365 |
RUVBL2,CCT8,RUVBL1,CCT7,CCT5,CCT2,TCP1,DKC1,NHP2 |
| 1.346e-02 | -4.31 | Rab protein signal transduction | biological process | GO:0032482 | 15 | 9 | 18204 | 5365 |
RAB4A,RAB33A,RAB39B,RAB33B,RAB9A,RAB35,CD2AP,RAB30,RAB9B |
| 1.346e-02 | -4.31 | cytoplasmic sequestering of protein | biological process | GO:0051220 | 15 | 9 | 18204 | 5365 |
G3BP2,SUFU,YWHAB,IL10,MDFI,FAF1,CCDC22,NFKBIA,PSMD10 |
| 1.346e-02 | -4.31 | BCL | smart domains | SM00337 | 9 | 6 | 9717 | 2575 |
BCL2A1,BAK1,BAX,MCL1,BCL2L1,BOK |
| 1.346e-02 | -4.31 | PAZ | smart domains | SM00949 | 9 | 6 | 9717 | 2575 |
DICER1,PIWIL2,PIWIL1,AGO1,PIWIL4,PIWIL3 |
| 1.347e-02 | -4.31 | haematopoietic_and_lymphoid_tissue-skin-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 58 | 25 | 16828 | 4835 |
HRAS,KRAS,IDH1,STK11,GNAQ,SMAD4,SF3B1,TP53,KIT,MET,RB1,GNA11,CTNNB1,FBXW7,IDH2,JAK2,PTPN11,AKT1,IKZF2,PIK3CA,FGFR1,MYD88,EZH2,PTEN,SMARCB1 |
| 1.349e-02 | -4.31 | FGFR1b ligand binding and activation | REACTOME pathways | R-HSA-190370 | 6 | 5 | 10285 | 3229 |
FGFR1,FGF10,FGF1,FGF3,FGF22 |
| 1.351e-02 | -4.30 | ISYNA1 (inositol-3-phosphate synthase 1) | protein interactions | 51477 | 68 | 28 | 19454 | 5460 |
EGLN3,SUMO3,PRNP,SPPL3,CYB5A,MSN,NAA30,PREP,CCNF,UBE2H,FBXW11,PPIB,CUL3,GRSF1,UCHL3,HSD17B10,ABCE1,HNRNPH2,HSPA8,RPA3,TPD52L1,CYB5B,UBE2M,PPT1,ACAA2,RPA2,EEF2,DUSP14 |
| 1.351e-02 | -4.30 | SLC1A3 (solute carrier family 1 member 3) | protein interactions | 6507 | 68 | 28 | 19454 | 5460 |
RAB5A,PMAIP1,KRAS,KCTD17,ZDHHC17,CDC42,MGARP,VAPB,PLD3,RAB35,HRAS,RAC2,SLC1A1,ARF6,MGST3,LGALS3,RHOJ,PRNP,RAMP3,CAV1,RAB2A,ATG9A,RAB11A,CUL3,LAMP3,LAMTOR1,RHOB,BTN2A2 |
| 1.351e-02 | -4.30 | BAZ2A (bromodomain adjacent to zinc finger domain 2A) | protein interactions | 11176 | 68 | 28 | 19454 | 5460 |
H2AX,ATP5PB,EIF4B,CBX3,LMNA,HAPSTR1,NUP50,RPL31,NLE1,SIRT7,RIGI,H3C1,ADRB2,DNAJC8,RACGAP1,SMARCA5,MYC,IFI16,CSTA,CHCHD1,DCAF4,EED,MACROH2A1,H2AZ1,FABP5,ZBTB2,VIRMA,SNRNP40 |
| 1.351e-02 | -4.30 | FAM193A (family with sequence similarity 193 member A) | protein interactions | 8603 | 68 | 28 | 19454 | 5460 |
EGLN3,VIRMA,APEX1,GSK3A,ANAPC2,LDLR,PHF21A,KRT8,CHCHD4,DCAF4,RC3H2,COP1,CNOT2,CUL3,CEP85,CTNNB1,KDM1A,CNOT7,STAU1,TRIM37,CNOT6L,RIGI,TCOF1,GARRE1,ZC3H7A,RNF113A,SQSTM1,ATG16L1 |
| 1.351e-02 | -4.30 | UBE2R2 (ubiquitin conjugating enzyme E2 R2) | protein interactions | 54926 | 68 | 28 | 19454 | 5460 |
RBPJ,SDCBP,PAK2,TULP3,SMYD3,UBR7,TPT1,PGAP2,KRAS,APPBP2,NUBP2,SIRT7,MAEA,USP15,MUL1,DRG2,FBXW11,STN1,YWHAH,CSNK2A1,YWHAG,CTNNB1,TCEANC2,IRF9,SFN,MDM2,SYT2,GNPDA1 |
| 1.351e-02 | -4.30 | GDF15 (growth differentiation factor 15) | protein interactions | 9518 | 68 | 28 | 19454 | 5460 |
CBX3,RAF1,PI15,TP53,TMEM106A,RANBP10,HSPA5,GID4,GID8,MAEA,MKLN1,PRKCB,SETD4,RMND5B,SQSTM1,TCEAL9,NTRK3,YPEL5,ARMC8,HTRA2,MDFI,ZMYND19,MSTN,CFC1,AR,STAT5A,MRPL50,CELA3B |
| 1.351e-02 | -4.30 | FOSL1 (FOS like 1, AP-1 transcription factor subunit) | protein interactions | 8061 | 68 | 28 | 19454 | 5460 |
CREB1,FAAP100,TRIM24,CEBPG,CEBPE,GGPS1,ELK1,JUNB,CREBBP,MYC,ATF4,ATF1,GCC1,LRRC20,COP1,KPNA1,TRIB1,ATF3,FBXO11,DDIT3,EP300,LDOC1,TICAM1,AHCYL1,POLDIP3,JUN,TAB2,PSMC3 |
| 1.351e-02 | -4.30 | RING | smart domains | SM00184 | 239 | 79 | 9717 | 2575 |
MNAT1,TRIM52,TRIM15,TRIM36,RNF128,RNF20,PCGF6,TRIM32,TRAF6,CGRRF1,TRIM26,TRIM5,RNF122,TRIM45,RNF121,TRIM46,TRIM11,TRIM68,BIRC2,RNF39,RNF103,PCGF2,RC3H2,RNF222,COP1,TRIM23,RNF139,RNF182,BRCA1,ZNRF1,CBL,RNF115,RNF113A,TRIM3,RNF187,RNF126,RING1,TRIM8,RNF34,TRIM27,TRIM21,SYVN1,TRIM22,RNF146,RNF144B,RNF181,RNF5,RNF133,TRIM35,LNX2,RNF41,TRAF7,TRIM62,RNF141,TRIM34,TRIM24,RBCK1,TOPORS,RNF10,BFAR,RLIM,RAG1,TRIM10,SHPRH,ANKIB1,RNF8,BRAP,RNF11,RNF148,RNF152,RCHY1,PML,TRAF2,RNF40,PCGF3,RNF167,TRIM63,TRIM6,TRIM54 |
| 1.355e-02 | -4.30 | UBASH3B (ubiquitin associated and SH3 domain containing B) | protein interactions | 84959 | 147 | 54 | 19454 | 5460 |
NCK1,SHC1,UBE2D1,CBL,SPTAN1,TCP1,HSP90AB1,CCT7,RCHY1,TNKS,KRT8,PSMB1,S100A8,CORO1C,DISC1,ERRFI1,SAP30,H1-3,ACTN4,WASL,HNRNPF,H1-6,RPS27A,HNRNPA2B1,CCT8,FAM168A,EWSR1,DCAF4,UBE2H,H1-1,TMEM255A,HSP90AA1,CUL3,PKP4,LMO2,CSK,TUBB,ACTB,VIRMA,JAK2,UBB,TUBA1B,UBASH3B,ACACA,TANK,SYK,SPTBN1,UBE2D3,KDM1A,HSPA5,RNF41,INPPL1,HSPA8,HNRNPH2 |
| 1.356e-02 | -4.30 | HSPA1B (heat shock protein family A (Hsp70) member 1B) | protein interactions | 3304 | 287 | 98 | 19454 | 5460 |
PSMD4,MATR3,PPP5C,AP2M1,LRRC28,PELI3,PSMD14,YWHAZ,HSP90AA1,NTRK3,DNAJB6,MYC,CUL2,CUL3,BTF3,ADRB2,STAU1,FBXL4,RCCD1,CRY1,NMRAL1,PSMA3,PPARG,PPT1,BORCS6,PHB1,AGR2,CBL,YWHAB,PDIA3,IFI16,CTNNB1,EPHA4,TRIM37,HNRNPA2B1,DNAJB4,BCL9,BAG2,RPN1,METTL21A,EZH2,GDI2,PLD3,ISG15,KCTD9,ADRM1,GMDS,SMURF1,VIRMA,STUB1,HEY2,UBASH3B,SPOP,TXNIP,EPHA2,CNTNAP1,ST13,KDM1A,PIK3R2,DVL2,INPPL1,BANF1,FLCN,SQSTM1,DERL1,FGFR1,SSR1,GRM2,MET,DYRK2,TRIM36,DENND2D,CDK7,CFTR,DCUN1D1,CAND1,TOMM70,EPHB6,AIFM1,SHC1,DNAJC7,STYK1,DNAJB2,CSNK2A1,COPS5,HDAC6,NEDD8,TOLLIP,RAB3B,MAP1B,DDR1,FAF1,IGF1R,NTRK2,RAD23B,KBTBD4,UBL4A,TP53 |
| 1.357e-02 | -4.30 | RBM33 (RNA binding motif protein 33) | protein interactions | 155435 | 110 | 42 | 19454 | 5460 |
NUP35,ERH,EGLN3,THOC1,FBXO22,RPL35A,FUBP3,EIF4A3,ALYREF,MAGOH,BRD3,CHTOP,FYTTD1,AR,API5,TIA1,XPO1,FBXO7,CSNK2A1,HNRNPA1,POLDIP3,SAP18,THRAP3,STAU1,SEM1,NUP50,RAB5A,BAG2,EWSR1,ZC3H11A,RPA3,DDX39B,IFT22,MAP2K1,CAAP1,RPA2,LMNA,DDX39A,SUPT5H,ZC3H14,ATG16L1,TOP3B |
| 1.357e-02 | -4.30 | SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)) | protein interactions | 2030 | 110 | 42 | 19454 | 5460 |
CDC42,TP53,SIGLECL1,RPN1,RAB5A,RAB9A,STX7,RAB3B,KRAS,LAMP3,CCR6,COPS5,RAB5C,GPR17,RAB11A,CREB3,RAB2A,LAMP2,TM2D2,DNAJB6,UPK1A,RHOB,RHOG,LAMTOR1,RAC2,CHRM4,RAB35,HRAS,S1PR4,APEX1,CAV1,SRC,CLRN2,DIRAS3,STX6,APLNR,TUBB,RHOJ,SPCS1,LGALS3,ARF6,CX3CL1 |
| 1.361e-02 | -4.30 | Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-112310 | 51 | 24 | 10285 | 3229 |
STXBP1,PPFIA3,SNAP25,RAB3A,SLC6A1,GAD2,STX1A,SLC38A2,SLC6A11,VAMP2,DNAJC5,PPFIA2,SLC6A12,LIN7C,ARL6IP5,SLC32A1,SLC1A3,SYN3,CASK,CPLX1,LIN7B,SLC1A1,SLC1A2,HSPA8 |
| 1.366e-02 | -4.29 | MED12L (mediator complex subunit 12L) | protein interactions | 116931 | 45 | 20 | 19454 | 5460 |
CDC5L,MED11,MED17,MED13L,HSPD1,MED4,MSRB3,MED31,CDK8,MED21,MED23,MED10,MED27,MED29,MED30,TTC23,AR,CKS1B,MED22,MED9 |
| 1.366e-02 | -4.29 | USP9Y (ubiquitin specific peptidase 9 Y-linked) | protein interactions | 8287 | 45 | 20 | 19454 | 5460 |
KRAS,MATR3,FBXO22,HS2ST1,DCLRE1C,AKT2,PHB1,RAMAC,TESK2,SHC1,VCPIP1,NCKIPSD,HEXIM1,EIF4B,CSNK1E,RSPH1,PYCR1,KANSL3,KIAA0408,MAP2K3 |
| 1.366e-02 | -4.29 | TRAF3IP2 (TRAF3 interacting protein 2) | protein interactions | 10758 | 45 | 20 | 19454 | 5460 |
HSD17B10,FHL3,IRF3,SRSF1,CD40,TRAF1,SPINDOC,TRIM63,UBE2V1,TRAF2,TRAF3IP2,RAF1,TBK1,SYK,MDFI,STK16,HSP90AA1,COP1,TRAF6,IKBKB |
| 1.366e-02 | -4.29 | ANXA4 (annexin A4) | protein interactions | 307 | 45 | 20 | 19454 | 5460 |
RPA3,DDX39B,RHOU,HSPA8,TRIM26,HNRNPL,MPST,TANK,NFKB1,RAF1,PDIA3,HADH,SOX2,H2AX,AGR2,RPA2,EZH2,SPOP,RNF8,ANXA7 |
| 1.368e-02 | -4.29 | TMEM86B (transmembrane protein 86B) | protein interactions | 255043 | 107 | 41 | 19454 | 5460 |
SEC22B,CCDC167,TMEM106A,OTULINL,STOM,USE1,VAMP2,TIMM23,CLRN1,CYB5B,STX12,TMX2,SLC39A9,STX8,TMEM203,ERP29,SLC35G2,DNAJC30,GPR37L1,TMEM60,VAMP5,TMEM107,ARL6IP6,FXYD6,FAXDC2,PLN,C2CD2L,SFRP1,TMEM14A,SSMEM1,PTPN1,VAMP3,RPRM,GJA1,THBD,MGST3,F11R,TMEM237,TMEM248,MSMO1,STX6 |
| 1.368e-02 | -4.29 | APLP2 (amyloid beta precursor like protein 2) | protein interactions | 334 | 107 | 41 | 19454 | 5460 |
RAF1,GINM1,B3GNT2,JUN,TMEM106A,CLEC2B,SFTPC,DISC1,CDK1,PIK3CA,NCR3,HGS,PRKCA,NOG,HDAC5,KRAS,APBB3,SFN,CUL3,CLEC18A,CFC1,AKT1,NONO,RPL26,BRCA1,SDF2L1,DEDD,AHSA1,MARCHF3,GXYLT1,PTPN1,ELSPBP1,CD1E,LMBR1L,SEC61B,TMEM74,NRSN1,GNAO1,RNF128,PRNP,JUNB |
| 1.368e-02 | -4.29 | MGME1 (mitochondrial genome maintenance exonuclease 1) | protein interactions | 92667 | 107 | 41 | 19454 | 5460 |
CITED1,ZBTB2,MRPS23,WIF1,EIF2B5,PRR3,TRIM45,GATD3,FAHD1,SSBP1,ALYREF,MRPS26,STYK1,FKBP4,MRPS25,TUFM,GRSF1,AUH,MRM2,PMPCA,OGDHL,MRPS17,PAEP,HNRNPH2,PICK1,COX8A,GFM1,HSPD1,EIF1AD,THNSL1,EXD2,RBPJ,MTRES1,RPA2,GDI2,FEM1A,ACAA2,PDHA1,NUP153,RAF1,MRPL11 |
| 1.368e-02 | -4.29 | HTR3A (5-hydroxytryptamine receptor 3A) | protein interactions | 3359 | 107 | 41 | 19454 | 5460 |
NLGN2,SPPL3,LRRC8A,GJA1,LRP12,GLT8D1,GRID1,C1GALT1C1,FITM2,FAM241B,SLC41A3,LRRC8C,ATG9A,TUSC3,CERS6,HSPA5,COA1,RHBDD3,GPM6A,BSCL2,SYVN1,SQSTM1,C1QL1,GPAA1,LRRC8D,ATP2B4,TSPAN15,CRELD1,POMT2,TMEM39A,FURIN,TMEM59L,TMX4,SLC12A2,PTRH2,SLC29A1,ST7,DIPK1A,GJC1,NETO2,FUT8 |
| 1.368e-02 | -4.29 | IWS1 (interacts with SUPT6H, CTD assembly factor 1) | protein interactions | 55677 | 107 | 41 | 19454 | 5460 |
UBE2H,DDX23,ELP6,XPO1,CSNK2A1,RNF40,HMGA1,MOV10,AKT1,AKT3,DHX15,APEX1,STAT2,FZR1,TOP1,SPCS1,CCDC71,SDHB,ENO1,ZNF330,PRCC,ALYREF,SF3B5,NUPR1,EZH2,RPA2,ACTR1A,E2F4,SUPT5H,FAM162A,SSRP1,HMGB1,HSPA8,RUVBL2,EP300,EMC2,TCEA1,RPL31,RPA3,SNRPA,TCOF1 |
| 1.369e-02 | -4.29 | PAFAH1B2 (platelet activating factor acetylhydrolase 1b catalytic subunit 2) | protein interactions | 5049 | 71 | 29 | 19454 | 5460 |
LDHB,TUFM,BAG3,YWHAG,COPS5,PSMG2,YWHAB,PAFAH1B3,MSN,RTRAF,CLVS2,EIF4H,IDE,PPP5C,PAFAH1B1,TPT1,BZW2,RPA2,OTULIN,RPLP0,HNRNPA2B1,RPA3,NAE1,RTCB,ARFIP1,HSPA8,TRIM63,ASF1A,GINS3 |
| 1.369e-02 | -4.29 | FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1) | protein interactions | 24140 | 71 | 29 | 19454 | 5460 |
CCNF,WDR6,APEX1,RHOH,CX3CL1,ARF6,DNAJC5,CUL3,WWP2,DPP4,PIK3R1,UBE2H,STYK1,EPHA2,NRP1,RHOB,LAMTOR1,NTRK2,RHOU,HSCB,EPHA4,KRAS,HCST,RND2,CDC42,CHRM3,WDR5B,RAF1,RND3 |
| 1.369e-02 | -4.29 | TSPAN17 (tetraspanin 17) | protein interactions | 26262 | 71 | 29 | 19454 | 5460 |
EPHX1,ADCY3,UBAC2,DDX39A,GNB4,HS2ST1,TMUB1,ACVR1B,GPM6A,BSCL2,FLCN,TMEM87A,BMPR1A,DDR1,LRP10,TMT1A,KCNJ8,TMEM199,KDSR,MOV10,RETSAT,DHRS7,HNRNPL,MGST3,SC5D,RETREG3,GJA1,GPR89A,HACD3 |
| 1.369e-02 | -4.29 | CRYBG1 (crystallin beta-gamma domain containing 1) | protein interactions | 202 | 71 | 29 | 19454 | 5460 |
PPP2R5E,KRT8,GSK3A,ESR2,RPL10,INA,ISCA2,XPO1,DEFB114,PPP2R5A,PTDSS1,CUL3,CSGALNACT1,AGPAT1,NPSR1,FOS,FBXO3,FBXL4,HNRNPK,G3BP1,RNF115,KDELR2,SGIP1,CCR1,STX17,NEFL,CAPZA2,SOST,EZH2 |
| 1.373e-02 | -4.29 | human chr2q32.1 | chromosome location | human chr2q32.1 | 19 | 9 | 26134 | 5823 |
DUSP19,DNAJC10,ITGAV,NUP35,NCKAP1,TFPI,FRZB,PDE1A,ZC3H15 |
| 1.373e-02 | -4.29 | Lipocalin | pfam domains | PF00061 | 30 | 15 | 17795 | 5224 |
FABP12,LCN1,RBP2,LCN12,LCN15,PTGDS,RBP5,FABP4,FABP7,PAEP,LCN8,LCN6,FABP5,PMP2,CRABP2 |
| 1.374e-02 | -4.29 | proton transmembrane transporter activity | molecular function | GO:0015078 | 171 | 65 | 18094 | 5411 |
NDUFV2,NDUFB6,SLC32A1,NDUFA12,SLC25A14,ATP5PD,COX6B1,COX8A,CHP1,COX5A,ATP6V1D,COX4I2,ATP5MC3,NDUFA2,SLC15A1,SLC25A27,SLC25A5,NDUFB10,SLC25A3,SLC15A2,NDUFA1,NDUFA5,NDUFB4,ATP6V1A,NDUFS8,CYB5A,ATP6V0E1,ATP5F1B,COX7A1,CYC1,NDUFB5,ATP6V1E2,SLC17A5,ATP5MG,NDUFS3,ATP6V1C1,ATP6V0B,ATP6V1G2,ATP6V1G1,ATP5PO,UQCRC1,UCP2,NDUFB8,SLC11A2,COX4I1,ATP5F1A,NDUFS6,SLC18B1,SLC16A1,SLC25A4,ATP5MC1,GHITM,SLC25A12,SLC45A3,ATP5PB,NDUFS2,ATP5PF,COX7B,NDUFC2,SLC38A3,ATP5F1D,UQCRH,NDUFB7,ATP5F1E,NDUFA4 |
| 1.374e-02 | -4.29 | STX6 (syntaxin 6) | protein interactions | 10228 | 444 | 146 | 19454 | 5460 |
VAMP2,STIM1,RAB4A,STX12,HGS,TMEM14B,MACO1,ARFGEF1,KRAS,GTF3C3,VAMP8,AHCYL1,TMEM87A,SCYL2,RINT1,MYO1B,RHOG,STX1A,ARMC8,LAMP2,MDFI,ATG9A,RAB5C,PPFIBP1,DDRGK1,OCRL,AFTPH,SNX2,RHOH,SPTAN1,VAMP7,MTERF2,GJA1,NRSN1,STX5,TRAPPC10,TMEM115,VPS18,MTMR6,GOSR2,NOTCH2,BET1,RND2,OTULINL,GOSR1,STX7,PSMA3,RAB5A,LAMTOR1,GCC1,MYO6,RHOB,SCFD1,SLC38A1,VEZT,NIBAN2,PKP4,RAB11A,CHST9,SCN3B,STX16,ESR2,FAM91A1,FAM83B,SURF4,TFRC,EXOC3,CTXN1,GNAI3,TSPAN3,CCDC47,SNAP29,SLC29A1,UBIAD1,MAP1LC3B,TMEM205,AKAP12,STX11,SLC6A8,CTNND1,STX8,DLG1,STX18,SEMG2,SNAP23,NOS1AP,ESYT1,OSBPL8,MOV10,LAMP3,VTI1B,SLC38A2,LMAN1,CAV1,SRPRA,EHBP1,CAMLG,SLC39A10,CDCA3,RAC2,PTP4A2,AP1AR,JUP,LMNA,VIPAS39,SLC12A2,STOM,GOLGA5,PICALM,VPS54,LEMD3,ATG16L1,RABL3,SPTBN1,TIMMDC1,ARHGAP1,SEC22B,CDC42,SYNRG,NAPG,YKT6,USP8,CLDND1,RHOU,RAB9A,STXBP6,ARFGAP3,NAPA,EPHA2,AP2A1,CSGALNACT1,CSK,VAMP5,ARHGAP21,IFNAR1,GORASP2,DNAJC5,RHOJ,YES1,VAMP3,GAB1,SMAP2,ENO1,SCAMP2,TMEM74,STX10 |
| 1.375e-02 | -4.29 | DLG5 (discs large MAGUK scaffold protein 5) | protein interactions | 9231 | 169 | 61 | 19454 | 5460 |
NTRK2,ZYX,FLOT1,TRIM37,KRAS,SOX2,RAF1,RHOBTB1,POLR2C,RND3,KRT8,GJA1,RAB35,CAV1,STX6,DIRAS3,RHOH,CTNNB1,CD81,YWHAG,YWHAH,SAV1,NDC80,YWHAB,STYK1,MED4,NCK1,RHOG,HSPA8,BTBD10,RHOU,SKP1,STX7,KDM1A,GTF2I,CDC42,RND2,PAFAH1B1,ATG16L1,TMOD1,FGFR1,CDK1,ANAPC2,GSK3A,MOB4,LURAP1,CTTN,CTNNA1,DLST,DYRK1A,ESR2,RHOJ,DYNLL1,DNAJC5,CUL3,MAPRE1,RIT1,NRP1,EPHA2,YWHAZ,RHOB |
| 1.375e-02 | -4.29 | HELLS (helicase, lymphoid specific) | protein interactions | 3070 | 169 | 61 | 19454 | 5460 |
H1-5,HCST,RPA2,LMNA,RPA3,SLC39A9,HELLS,PML,SERTAD2,EP300,UBE2K,UCHL3,STAU1,FBXW7,COIL,HSPA5,SLC25A1,MYC,CUL3,FOXA3,DNAJC8,F9,LMNB1,H1-10,H1-1,CCNF,CD79B,LMBR1L,ZNF330,MACROH2A1,TAX1BP1,FBXO22,UBE2L3,MAD2L2,APEX1,TP53,RPAP2,H1-3,EZH2,CBX3,FURIN,CYB5B,RPL31,RPAP3,EMC2,H3C1,SEMA4C,DPM2,RIGI,UBXN6,LAMP2,DDX23,LHX2,BRD3,ANKRD50,UBE2N,FBXO32,EEF1AKMT3,ARL4D,FZR1,CDC5L |
| 1.375e-02 | -4.29 | BORCS6 (BLOC-1 related complex subunit 6) | protein interactions | 54785 | 169 | 61 | 19454 | 5460 |
WTAP,BORCS8,SCLT1,CDR2,BORCS5,BORCS6,UQCRC1,NDE1,NUP62,UQCC3,RAB9A,INPPL1,CCHCR1,EXOC8,BICD2,PKNOX1,CCDC22,BLOC1S5,LAMTOR1,NTAQ1,FBXO44,GSTM5,RNF40,EPS8,VPS39,FCHSD2,BORCS7,UBB,UQCRQ,LAMTOR3,ZNF655,SELENOT,HGS,PSMC3,CCDC122,DISC1,IFT57,SPG21,SNAPIN,TBK1,SNAP29,TRIM37,BAG2,BLOC1S2,RINT1,CAMSAP2,PPM1B,MED21,GAS8,LAMP3,INSYN1,NDC80,LAMTOR2,KXD1,LAMP2,HSBP1,CNTROB,UQCRH,SHPRH,SNX2,XXYLT1 |
| 1.376e-02 | -4.29 | somatic diversification of immune receptors | biological process | GO:0002200 | 54 | 24 | 18204 | 5365 |
SWAP70,RAG1,SHLD1,SAMHD1,LIG3,EXOSC3,MAD2L2,POLB,HMCES,CCR6,MSH6,NHEJ1,STAT6,RNF8,DCLRE1C,CD40LG,NBN,BATF,HMGB1,POLL,FOXP3,CTNNBL1,HSPD1,BCL6 |
| 1.376e-02 | -4.29 | cell surface receptor signaling pathway via STAT | biological process | GO:0097696 | 54 | 24 | 18204 | 5365 |
STAMBP,GH1,IL15RA,IL21,IFNAR1,SOCS2,CCL2,IL15,IFNB1,JAK2,STAT1,IFNG,NMI,CSF2,CCR2,PIAS1,STAT6,IFNA2,LEP,STAT5A,SOCS5,GHR,STAT2,JAK1 |
| 1.377e-02 | -4.29 | HMGN1 (high mobility group nucleosome binding domain 1) | protein interactions | 3150 | 144 | 53 | 19454 | 5460 |
TOP3B,STBD1,RAF1,H2AX,MSX2,MAGEA4,NGB,PCNA,G3BP1,FGD2,H3C1,ANP32B,NFE2,CALR,PDIA3,PGAM1,PPIB,ACTR3B,SPP1,ANKRD49,H2AC4,BRD3,SLC38A3,MIF,SUMO2,MDM2,LCP2,SLAIN2,ATG16L1,CDC42,MND1,CTBP1,PRKCA,PEBP1,DDX39B,SOD1,PGK1,ATP5IF1,PMAIP1,EP300,AKT3,ARHGAP21,H2BC9,PPP1CC,YWHAZ,RPS6KA4,IRF2,PARP2,GSK3A,MACROH2A1,TRIM24,HPF1,APEX1 |
| 1.378e-02 | -4.28 | RRP7A (ribosomal RNA processing 7 homolog A) | protein interactions | 27341 | 104 | 40 | 19454 | 5460 |
GADD45G,ESR2,RPS10,MATR3,HP1BP3,RPS20,NAP1L5,RPS3,RPL9,ZNF330,RPS5,CRMP1,ARMC7,UBE2H,MECP2,RPL24,ANAPC15,GNG2,MPG,MYC,HNRNPC,CDCA7L,G3BP2,UTP23,KRAS,ZNF692,RPL4,RPS24,RPL31,SIRT7,RPS11,TFIP11,RPLP0,HBP1,RPL18,NCSTN,RPS7,STXBP1,H2AJ,RAF1 |
| 1.378e-02 | -4.28 | COMMD4 (COMM domain containing 4) | protein interactions | 54939 | 104 | 40 | 19454 | 5460 |
DHX15,COMMD6,VPS26C,GGT7,RBMX2,COX20,PSPC1,APEX2,RSRC1,PFDN4,ATP6V1D,COMMD9,TFDP2,CCDC22,H2AC4,RNF40,COMMD5,MYC,SUGP1,NFKB1,SUB1,RBM17,IMMP2L,PACSIN3,SSRP1,MCMBP,EXOSC4,SF3B1,COMMD2,ARGLU1,CNKSR3,SCLT1,E2F6,RAD23B,STMN2,TUBA1A,TSHR,COMMD3,NUP62,COMMD8 |
| 1.378e-02 | -4.28 | SHKBP1 (SH3KBP1 binding protein 1) | protein interactions | 92799 | 104 | 40 | 19454 | 5460 |
RAC2,OLFM2,GLTP,CIB2,EEF1AKMT3,HSP90AB1,ESR2,CEP97,APEX1,EGLN3,MIF,RHOJ,KCTD3,DCUN1D1,HNRNPL,KLHL22,FEM1B,YWHAH,BTF3,YWHAG,XPO1,ATG7,COPS5,CUL3,IFI35,TNFAIP3,YWHAB,HSP90AA1,BAG2,NUBP2,FHL3,P4HA2,PTPN4,NEDD8,CDC42,WDR83,DYRK2,UBE2M,NHERF1,LXN |
| 1.378e-02 | -4.28 | PTPN9 (protein tyrosine phosphatase non-receptor type 9) | protein interactions | 5780 | 104 | 40 | 19454 | 5460 |
SLC7A1,GJB1,SMN1,PSMD12,STX7,ATP5PF,TMT1A,RPA3,STX8,TMX2,YIF1A,PC,SLC39A7,TTPAL,RAB4A,RPA2,LMNA,GHR,AGTRAP,QTRT2,DERL2,CCR2,VTI1B,MTM1,VAMP7,STX6,ENO1,CCNF,HSD17B11,GEMIN8,PDCD1,SYP,LAMTOR1,UBE2H,REEP6,PMPCA,ATG9A,MOV10,CREB3,MYC |
| 1.378e-02 | -4.28 | SLC18A2 (solute carrier family 18 member A2) | protein interactions | 6571 | 104 | 40 | 19454 | 5460 |
NEK7,HACD2,SLC29A1,SYNGR2,SLC25A24,OTULIN,CSNK1A1,TTI2,EXOC3,GPD2,NDUFC2,TMEM126B,SLC6A3,JAK1,TOMM6,RNASEL,PXMP2,UFL1,SLC7A1,DNAJC5,MZT2B,ORMDL3,CSNK2A1,EXOC5,ORC5,RAB32,RAB3A,EXOC2,DOLK,PTPMT1,MFSD5,SERINC1,ELOVL4,TLCD4,RAB39B,SLC25A17,FUNDC2,NDFIP1,ADCK1,COG1 |
| 1.378e-02 | -4.28 | AGFG1 (ArfGAP with FG repeats 1) | protein interactions | 3267 | 104 | 40 | 19454 | 5460 |
RDH12,SH3GLB1,PPME1,FGFR1,RAB4A,RPA2,P3H1,PAQR3,BET1,KBTBD4,TBK1,LAP3,STX7,STAU1,RHOU,BAP1,RPA3,NTRK3,RHOB,LAMTOR1,NIF3L1,KLHL22,DNAJC5,YWHAG,FCGR2A,XPO1,YWHAH,RAB11A,PKIA,ATG9A,CEP19,ESR2,STX6,VAMP7,NYAP2,MPP1,RHOJ,TRIM54,SURF2,SMAP2 |
| 1.382e-02 | -4.28 | FGFR2b ligand binding and activation | REACTOME pathways | R-HSA-190377 | 10 | 7 | 10285 | 3229 |
FGF1,FGF10,FGF22,FGF7,FGFBP2,FGF3,FGFBP1 |
| 1.382e-02 | -4.28 | SLBP independent Processing of Histone Pre-mRNAs | REACTOME pathways | R-HSA-111367 | 10 | 7 | 10285 | 3229 |
SNRPE,SNRPB,ZNF473,LSM10,SNRPG,SNRPD3,NCBP2 |
| 1.382e-02 | -4.28 | Removal of aminoterminal propeptides from gamma-carboxylated proteins | REACTOME pathways | R-HSA-159782 | 10 | 7 | 10285 | 3229 |
FURIN,F10,F9,PROS1,BGLAP,F2,F7 |
| 1.382e-02 | -4.28 | Acetylcholine regulates insulin secretion | REACTOME pathways | R-HSA-399997 | 10 | 7 | 10285 | 3229 |
GNA14,GNAQ,PLCB1,PLCB2,GNA11,CHRM3,PRKCA |
| 1.382e-02 | -4.28 | MAPK3 (ERK1) activation | REACTOME pathways | R-HSA-110056 | 10 | 7 | 10285 | 3229 |
IL6ST,JAK1,IL6,MAP2K1,CDK1,PTPN11,JAK2 |
| 1.382e-02 | -4.28 | Gamma-carboxylation of protein precursors | REACTOME pathways | R-HSA-159740 | 10 | 7 | 10285 | 3229 |
PROS1,BGLAP,F7,F10,GGCX,F2,F9 |
| 1.383e-02 | -4.28 | RNF6 (ring finger protein 6) | protein interactions | 6049 | 74 | 30 | 19454 | 5460 |
AHCYL1,LDOC1,STX11,TRIM37,ARPC2,MYO1B,RINT1,GNA11,GNAI3,TFIP11,PNMA2,CD59,TP53,GNAI2,SPTAN1,TAX1BP1,CORO1C,TRIM27,UBE2H,SSX2IP,CDKN1B,BRCA1,TRIM23,UBE2D1,CTNNB1,STK4,CEP70,AR,LDB1,MDFI |
| 1.383e-02 | -4.28 | CDC42EP4 (CDC42 effector protein 4) | protein interactions | 23580 | 74 | 30 | 19454 | 5460 |
RHOB,LAMTOR1,RHOG,YWHAH,SURF6,CAV1,ESR2,SRPK2,RABL2B,HOMER1,RHOJ,RHOH,ARF6,POLR3H,RAC2,YBEY,CALML5,SNX12,RAB35,HRAS,WDR6,RNF146,POLR1D,CDC42,STX7,KRAS,KLHL15,SEPTIN7,RHOU,SEPTIN6 |
| 1.383e-02 | -4.28 | TARBP1 (TAR (HIV-1) RNA binding protein 1) | protein interactions | 6894 | 74 | 30 | 19454 | 5460 |
HNRNPD,FIS1,CSK,SCN3B,CUL3,GPR17,DLK2,GMNN,PRNP,EGLN3,SLA2,CCNF,LMBR1L,SYNCRIP,SCN2B,CD79B,RAB6B,CYB5B,PIH1D1,FAM234A,DLG3,HCST,FAF2,NPTN,RASL10B,RP2,HSPA5,OSTM1,CXCR4,AKAP1 |
| 1.383e-02 | -4.28 | ARL6IP6 (ADP ribosylation factor like GTPase 6 interacting protein 6) | protein interactions | 151188 | 74 | 30 | 19454 | 5460 |
YWHAG,YWHAH,NAA50,RAB5C,TRAPPC4,PNPO,YWHAB,YWHAZ,SPINT2,CBFB,LMBR1L,CLRN2,DUSP3,MSMO1,MGST3,SNX3,CRTC2,TMEM205,TIMMDC1,E2F4,KLC2,MET,ACTR2,ARPC2,RUSF1,PYGB,ARL6,RNF5,YKT6,LPAR1 |
| 1.383e-02 | -4.28 | Ktn1 (kinectin 1) | protein interactions | 16709 | 74 | 30 | 19454 | 5460 |
RPL7A,PTDSS1,IFI16,KARS1,RPS17,H1-10,POLB,STT3A,CCNF,EEF1B2,RPL13A,RPS27L,RPS16,RPL22,ERLIN1,H1-5,RPL27A,MACO1,RABL3,ERLIN2,CDC42,VAPB,RARS1,RPS24,EEF1G,CCDC186,MARS1,H2BC14,CTSC,BRIX1 |
| 1.386e-02 | -4.28 | endometrium-ovary-endometriosis | COSMIC cancer mutations | endometrium-ovary-endometriosis | 13 | 8 | 16828 | 4835 |
TP53,BRCA1,KRAS,CTNNB1,HRAS,AKT1,PIK3CA,PTEN |
| 1.386e-02 | -4.28 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Hodgkin_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Hodgkin_lymphoma | 13 | 8 | 16828 | 4835 |
IDH2,PIK3R1,JAK2,IDH1,CDKN2C,MYD88,EZH2,TNFAIP3 |
| 1.386e-02 | -4.28 | upper_aerodigestive_tract-sinonasal_and_nasal_cavity-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-sinonasal_and_nasal_cavity-carcinoma-undifferentiated_carcinoma | 13 | 8 | 16828 | 4835 |
KIT,CTNNB1,KRAS,JAK2,AKT1,FBXW7,PIK3CA,EWSR1 |
| 1.387e-02 | -4.28 | ARFIP2 (ADP ribosylation factor interacting protein 2) | protein interactions | 23647 | 101 | 39 | 19454 | 5460 |
ARF4,CCAR1,SOCS2,BLOC1S2,EWSR1,ARFIP1,RUSF1,SH3GLB1,HGS,SDCBP,TMEM31,DMAP1,RAB4A,NFE2L2,PPIF,ING1,NRDE2,PLP2,DUSP22,MIEF1,NUP62,AGTRAP,ING5,STX6,TRIM54,ARF6,SNX1,RAC2,ARF1,SMG9,SNX5,SYP,SCAMP5,LAMTOR1,BICD2,MOV10,AKT1,CSK,RAB11A |
| 1.387e-02 | -4.28 | AGTR1 (angiotensin II receptor type 1) | protein interactions | 185 | 101 | 39 | 19454 | 5460 |
SCG5,HRAS,PNMA1,AP2M1,SERINC3,JAK2,CAV1,VKORC1L1,RAB11A,DNAJC8,ATP1B1,PSMD10,FBXW11,TMEM11,SETD7,CCDC25,OAZ1,TSPAN15,ATP2B4,GPAA1,RAB5A,BAALC,SLC16A1,JAK1,NPTN,CERS6,SLC6A8,SLC19A2,AGTRAP,FAM13B,ARFGAP1,RAF1,SPG21,RAB4A,JKAMP,GHITM,PTGFR,VAC14,SELENOF |
| 1.387e-02 | -4.28 | KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2) | protein interactions | 11014 | 101 | 39 | 19454 | 5460 |
MET,CFTR,PLP2,MAP2K3,KDELR2,CDK4,H1-5,GINM1,CSNK1E,DUSP14,LYG2,GDPD3,NF2,TNFSF8,IGF1R,VIPR1,POU5F1,EPHA2,STK11,BECN1,SPOP,SLC2A1,WDR11,MZT2B,CIAO1,FAM174A,AKT1,MYC,SERINC3,GNAI2,RAMP3,TRIM29,GRM1,HNRNPL,MACROH2A1,CDK6,EDNRA,PHB1,FAM91A1 |
| 1.387e-02 | -4.28 | TMEM63A (transmembrane protein 63A) | protein interactions | 9725 | 101 | 39 | 19454 | 5460 |
SLC4A8,RPA2,SURF4,KDELR1,GHITM,UBAC2,SIGMAR1,YIPF4,SLC29A1,SLC51A,TMEM126A,TPRA1,AGTRAP,PIP4P1,DERL1,RPA3,TMEM87A,ATP2C1,AP3S2,DOLK,LGALS8,RIOK2,SLC41A3,CCR6,TMBIM6,MYC,GPR37,VKORC1L1,MSMO1,ALG5,CCR2,HNRNPL,SC5D,LGALS3,SLC30A7,MFSD5,SERINC1,PTPN1,ARL10 |
| 1.388e-02 | -4.28 | FOS (Fos proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 2353 | 284 | 97 | 19454 | 5460 |
ASF1A,ENKD1,COPS4,ATF3,MYO1B,FHL3,BCL9,SCHIP1,SMARCB1,ARFGAP1,VDR,JUN,PPP2R1A,GTF2E2,MITF,SUMO2,SUMO3,CYTH4,ELK1,PHB1,FAAP100,UBE2D1,KDM2A,NQO1,GNG11,BCL7C,LYG2,SMARCD3,HIRA,FOS,EP300,PSMA3,DDIT3,CRYAB,GAMT,DUSP14,PGRMC1,DET1,ELK4,LMO3,STAT1,MED17,VEGFA,GTF2F1,GTF2F2,RPS6KA4,MYO6,COP1,TRIB1,CREBBP,SMARCE1,BRMS1,PAGR1,RIGI,MAP1B,PPP1R12A,ARPC3,TRAPPC13,TP53,BATF,RPL35A,TSC22D3,MDM2,MYL12A,SMAD3,SSBP1,SSU72,CEBPG,RB1,TMOD2,NFKB1,TLE1,NR2F6,CSNK2A1,GLO1,TPM3,HMGB1,CLU,SS18,PML,LMNA,CCND1,SUMO1,XBP1,TMOD3,CEBPE,UBE2L3,JUNB,OPTN,UBN1,MID1IP1,CALML5,PSMC5,UBE2I,TRIM24,ATF4,RUNX1 |
| 1.389e-02 | -4.28 | negative regulation of small molecule metabolic process | biological process | GO:0062014 | 114 | 45 | 18204 | 5365 |
AKT1,MIR132,FMO1,CH25H,INSIG2,KLHL25,PROX1,PPARA,FBP1,DDIT4,MIR98,ETFBKMT,ERLIN2,TP53,MIR675,MIR185,ADIPOQ,EP300,FMO2,NUPR1,LEPR,FLCN,IER3,PID1,SOX9,BRCA1,MIR342,GFI1,TSPO,CNR1,DCAF5,MIR21,SOD1,TRIM63,FIS1,SNAI2,CYP7A1,MIR204,CYP27B1,ATP2B4,DKK3,GSK3A,CRY1,NFKB1,ERLIN1 |
| 1.392e-02 | -4.27 | nucleic acid binding | molecular function | GO:0003676 | 4273 | 1336 | 18094 | 5411 |
SAP18,MIR335,MIR340,SUPT5H,ELF1,MGMT,XRCC5,ZGLP1,EIF3J,EIF3K,ZNF704,NR4A2,TSG101,PPP1CC,MIR572,SHPRH,BANF1,SNAPC1,THAP6,EIF3D,TAF2,DNAJB6,HNRNPA2B1,NUDT4,NGRN,ARCN1,NABP1,ILF2,HSPB1,MRPL16,SSRP1,EIF4H,NFIL3,PAIP2B,RBM15B,VDR,SERPINA3,PABPC1,MACROH2A2,LMNB1,ISX,MIR302B,TES,MRPL11,ELK3,MIR23A,EIF3E,MRPS35,COPS5,EIF1AX,RPL7,MIR455,H1-10,LSM2,LSM12,DR1,SLC25A11,MAP4,UBP1,PIH1D1,MIR429,CCDC9B,ADK,RBM12,RPL4,SECISBP2L,FOXJ3,FUBP3,MIR137,TRMT1L,JCHAIN,NLRP6,DRAP1,G3BP1,ZNF664,CDKN2AIP,HNRNPK,RFC4,POLDIP2,ORC6,RTL4,RNASE6,MIR146A,MIR142,THOC1,IRF1,MIRLET7C,HSPD1,CSRP1,EP300,VIRMA,SNRPA,PCBP4,MBD5,ADNP,MTRF1,GTF2I,RNASEL,MIR214,MIR148B,MAEL,MRPS18C,MIR505,ZNF511,RBMS2,TLR9,MIR223,ATF3,RBM7,H1-5,COIL,FEN1,TOX4,LGALS3,RPSA,TFE3,BRIX1,MIR345,RPL23,TCF23,MARS1,MIR330,THOC6,GRSF1,FOXD3,CEBPE,IFIH1,RPL19,NEUROD6,POLR2F,PSMD4,RPS13,FOXP3,HR,MTA2,GABPA,EGR1,BUD23,MIR140,TIGD7,EEF1B2,SNRPN,NOP58,MIR346,G3BP2,ZNF575,TP53,EEF2,NR0B1,CELF6,THUMPD1,RPL32,SNRPD2,SRP72,LDB1,EIF5B,SOX3,ZBTB38,SEC63,FAM133B,E2F4,MIR181C,RBM38,DCP2,MIR185,POU5F1,NONO,MIR497,MTERF2,RBMX2,HLF,ZNF473,NDN,KCNIP3,HOXB8,UTP15,DGCR8,ZMPSTE24,PRRC2A,AKAP8L,MIR211,MIR129-1,SRSF10,E2F6,ATF4,MIR640,TLR7,STAT5A,PROX1,ZNF362,ZBTB6,PQBP1,PLSCR1,ZNF174,SPATS2L,SREK1IP1,SLC25A5,DDX39B,PRIM2,NEUROD2,RPL15,MIR379,MLH3,RPS11,PML,TFPT,MIR638,RTN4,DTD1,MIR34C,RPL9,PIWIL4,MIR92B,TOP2B,RPP21,ZNF622,NOL7,RPL28,CPSF1,AR,ADD1,SOD2,CARHSP1,ZHX1,ELF5,MOV10,MIR193B,NLRP3,TOPBP1,PARP2,MRPS17,CRY1,SMN1,OAS1,TIA1,NME2,EZH2,TNRC6C,SURF6,NKX6-2,HNRNPH3,STN1,ZNF518B,MIR495,LSM8,ALB,PSPC1,MIDEAS,ZNF177,SPRN,HNRNPD,DUSP14,ZNF770,RNASEH1,HNF1B,MIR3173,KIN,DDIT3,SIX5,PHF1,SNAI3,VPS72,RPS27L,ZNF326,TUFM,FOXA3,XPOT,SF3A1,TCOF1,HMGA1,POLR1B,UBFD1,PIWIL2,HSP90AB1,NPM3,SNRPB2,CERS6,RAMAC,AGO1,FOS,KLF1,H1-1,THAP2,GTF2IRD1,RBFOX3,AKAP17A,JUNB,AHCYL1,MIR215,BCL6,NFE2,SIN3A,MIR383,SRPRA,CARS1,DXO,MIR126,UBE2L3,RRN3,MRPS23,MIR657,ZSCAN5A,RPS3,HMGN4,MIR374A,POLA2,GCFC2,ROCK2,FOXP2,MAFG,MAX,MIR181D,PRPF31,HMGB1,EIF3G,FANCG,RFX4,SMAD3,ZBTB18,CCT5,SMG5,H2AZ1,MIR194-1,DTD2,ZYX,EEF1A1,JAKMIP1,H2AC6,CPSF4,RBBP7,TFEB,TENT5C,BARX2,GTF2E2,BHLHE40,TST,RBBP4,NCOA5,WDR3,EHD4,TRIM27,CRYZ,ACO1,PPIL4,TRIM32,ZBTB2,MIR208B,MRPS28,MIR491,HNRNPDL,MIR661,KCTD12,CCDC25,RPL13A,WDR77,VRTN,MIR183,PSMC1,RPS16,TRIR,MRPL12,POP5,UTP6,APOBEC3B,MIR208A,RFX5,THG1L,THAP1,MIR191,MIR874,RPL35A,ZMYM6,SWAP70,ZHX3,MSX2,YWHAZ,SRSF12,MIR1-1,SNRNP70,KHDC1,PCSK9,ESR2,SP1,MIR493,HSP90B1,CDK9,ZCCHC10,PPIB,MIR296,NOL12,DHX38,CSTF2T,MIR21,POLB,ZBTB39,MFAP1,ZBED3,MIR363,TACO1,CTNNA1,POLR2B,MPHOSPH6,LITAF,ZCCHC9,MRPS11,DHX16,H2AC4,NHP2,RUNX1,SNAPC3,MRPL13,RPL7A,ACTB,SNAI2,ZNF688,DEDD,MEIOB,ZBTB16,CMSS1,MND1,HEXIM2,H2AX,MRPL23,ZBTB17,NOA1,RFXANK,RPP25,AKAP1,DNAJC2,ZNF655,NOVA1,PCNA,MYEF2,PEBP1,TFDP2,PHF21A,MIR10A,LSM6,TRIM26,SNRNP27,XBP1,LUC7L3,MIR125A,RAG1,TFCP2,ZNF592,TSN,RTCB,RPS10,MCM6,LHX2,POU1F1,FLYWCH2,HEY2,RPS15,MITF,DNTT,H2AZ2,APEX2,E4F1,MIR100,HMCES,TAF9,MIR99A,RPL8,BEND5,LSM10,CHTOP,CIART,DICER1,BOLL,ZBTB14,SNRNP40,RPL24,MIR30E,ZNF451,NUDT16,NKRF,CDC40,TERT,MPHOSPH10,MDM2,PRM1,KDM2A,RPS27A,APOBEC3C,MTF1,ZNF280B,RXRG,PPIG,H1-3,PPP1R8,NSA2,ING2,POU3F4,ZNF787,APEX1,TRIM24,HNRNPF,ZNF397,PPAN,RPS4X,HNRNPA0,POLR2G,EIF2B3,TOX,MIR96,POLE4,ZNF343,RPF2,PHC1,IRF4,RPL39,TSNAX,PNO1,MRPL10,RBM3,CCDC86,ASCC1,EMX1,MAK16,ATXN1L,ZCCHC7,IKZF2,SSBP4,RBM42,NFYA,MIR192,SMARCE1,IFIT2,LIG3,ETV6,ZKSCAN1,RPF1,POLL,SNRPD1,PAPOLB,SMC4,HUWE1,RBFOX2,MCM8,ZNF740,MIR153-1,EZH1,FYTTD1,MIR15A,EIF1AD,LLPH,H2AB1,UBE2I,MIR1224,NUDT5,FTSJ3,ZBTB42,MIR205,LEP,R3HCC1,KLF12,DROSHA,POLR1D,USP3,QTRT2,MRPL24,CNOT8,UTP23,MIR449A,RTRAF,NUPR1,ZNF501,CERS2,PABPC5,ZSCAN1,RPS12,EMG1,NUP35,APEH,PDAP1,MIR16-1,MIR99B,NFE2L2,SUB1,PPP1R10,RPS20,RPA3,STRBP,DDX5,NUFIP2,IKZF5,FARSA,BTF3,CALR,MIR877,EDC3,ZFAND6,SAP30,WBP2,ANP32A,NLRP1,RPS24,SYNCRIP,EIF2S2,ZC3H15,FOXS1,MPG,MIR150,IRF8,MTA3,MIR26B,IRF2,RNF11,ZNF263,PPARG,ARB2A,ZNF189,METAP2,TRMT11,MIR187,ELAVL4,TRA2B,MSN,ELK4,NHEJ1,SOX14,KDM1A,YAF2,TYMS,DHX9,MEF2C,ZC3H7A,ZNF513,EIF2S1,EIF4A3,ZSCAN25,TGIF2LX,RPS7,FAM98A,UNC50,POLR2L,SNRPA1,CRKL,CPSF2,TRIM21,BRD9,GTPBP1,TNFAIP3,WBP11,MIR876,LSM4,RIGI,SMCHD1,TRNP1,NEUROG2,SAMHD1,HMG20A,RFC5,H2BC9,RNASE1,RBM22,SNIP1,TMPO,NUP42,JUN,MIR130A,GEMIN7,ADAT1,MIR20A,LYAR,LBR,RMI2,MIR222,STAT1,MAGOH,ZNF671,BEND6,CCAR2,POLR2I,OTUD7B,RADX,CRLF3,SEC61B,MIR552,SMUG1,GFM2,HSP90AA1,H2BC1,MIR9-1,MIR148A,PRDX1,SERPINH1,ALKBH5,PRKRA,RORB,PTPN1,HDAC6,LSM5,DRG2,ETF1,APTX,NUDT7,TBK1,SMARCB1,RNASET2,MRPL9,DHX15,SRSF1,PELP1,PNMA3,GTF2F1,ZNF287,KLF3,PWP2,NOP9,MIR149,CSNK1E,RNF20,AATF,NCBP2,RBBP8,HMX2,CHRAC1,RAD23B,FASTKD5,MIR141,MIR590,DLX1,NUCKS1,ACTN4,IRF7,RPL27A,MIRLET7B,ELP3,ZBTB33,MIR106A,TCP1,IMP4,BAP1,MIR143,UTP25,ZNF593,NOSIP,MAP1S,MIR182,PAX6,NTPCR,NME1,SNRPE,ZNF175,MIR492,CMTR1,ALKBH2,DDX42,RPL3,MIR551A,FOXP1,SOX9,ZCCHC12,PPME1,TEF,HP1BP3,HAND2,SMAD9,MRPS21,RPS2,NKAP,MIR339,PHAX,MIR573,ABCF1,ZNF304,MIR30A,TGIF2,SCG3,GPBP1L1,PDCD4,MIR424,WDR6,NR2E1,RPA2,TDP1,RPS26,TRMT10B,GTPBP2,FXR2,EIF2B5,ZNF687,KLF4,RFC2,POLR3F,MTPN,H2BC14,MIR198,MTRES1,DDX4,SMAD2,RPS5,RPS23,METTL14,RDM1,MIR17,ZMYND11,CGGBP1,MIR885,CREBBP,MRPL18,PRR3,MIR136,TAL2,SF3B1,MIR1298,PIWIL3,MRPS18A,KLF10,ZNF207,MIR298,MIR145,FAAP100,TRMT6,NKX3-2,TNF,PLAGL1,EIF4E,SSBP1,ELK1,GDI2,BACH1,CSTB,RPLP0,TPT1,H2AJ,MECP2,EIF4B,MIRLET7G,FOSL2,ZNF7,TAF1D,RP9,MIR708,RFXAP,WRAP53,MIR361,MIR639,MAGOHB,IRF9,ZMYM3,MATR3,UBE2N,ZFP1,R3HDM4,TUBB4B,ZCRB1,CREBZF,MIR423,STAU1,NUP153,FKBP4,MIR206,CREB1,DDX39A,MIR212,MIR384,MIR503,CSTF3,DNAJC1,ZNF345,EXOSC1,MIR221,MIR106B,TDRD7,TFB1M,MIR190B,ZNF805,PCGF2,RBPJ,ELAVL2,GTF3C3,IFI16,MYBL2,H2AC7,CNOT7,RB1,MIR873,MIR1271,GTF2A1,GIN1,MIR107,MIR675,SUMO2,ZNF250,ZBTB5,H2BC11,PABPC1L,TYW5,DRGX,PIWIL1,SPTBN1,THRAP3,SHOC1,EWSR1,NACC2,MIRLET7I,RBM27,HOXC4,ZNF267,PKNOX1,PPIA,RPP25L,ISG20L2,RBM5,H2AC25,HOXD12,GFI1,MIR519D,HNRNPL,CASC3,MIR488,CPEB1,TERC,SOX2,RPS9,NR1I3,SF3B4,MACROH2A1,RPL27,RPP14,SAP30L,ZRANB2,EEF1G,H3C1,LARP4B,HELT,SNRPG,MIR425,ZNF319,TCEA2,MIR210,SRP14,RPL35,INSM2,TRA2A,PAPOLA,MIR29A,RPS14,HINFP,MIR338,BCCIP,PGR,KRR1,IGF2BP1,PAIP2,HNRNPAB,CYFIP2,KARS1,TOP3B,OSR2,RAD21,BRD3,MIR378A,NR1H2,ACTL6A,ZC3H11A,RPS28,ALYREF,RPL31,HENMT1,SF3B5,RALYL,MIR30B,MIR144,LSM3,RBM34,ZBTB25,KHDC4,MRPL22,EMX2,STOX2,SRSF4,MRPL41,SUMO1,PSMA6,EIF4E3,MCM3,UBN1,H2BC12,MIR28,PAIP1,RPL23A,RPL26,SART3,RPL17,NFYB,EIF1B,LBX1,ZMAT3,MRPL40,MCM4,MIR511,KIF1C,NFKB1,RPL10,DEK,RPL29,IFT57,MEF2B,MIR10B,EXOSC8,MIR147A,H1-6,PYM1,RBM17,RPL10A,CGAS,BATF,MIR101-1,SRSF8,ERH,APOBEC3G,DNTTIP1,HBP1,SMARCA5,EIF4E2,MIR490,ZBED4,ENO1,PEG10,JRKL,SUV39H1,FOXI3,HNRNPH2,NKX3-1,BHLHA9,EIF5A2,MIR320A,MBD3,CENPW,RPL22,TSEN34,CDC42EP4,APOBEC3H,HNRNPC,ATF1,MRPS9,PDIA3,POLR3H,PDCD5,STK16,MIR301A,RNASE9,TLR3,MIR342,NBN,MRTO4,REXO2,MCAT,ARF1,ZBED1,THAP7,ZNF821,YTHDF1,CDC5L,LCORL,RPL37A,MIR1260B,EIF2AK2,ZNF322,RAN,H2AC1,MRPS7,EIF4A2,UHMK1,GABPB1,MIR34A,SNRPB,SRPK2,CHCHD2,HSD17B10,NFE2L1,PRDM4,CSRNP3,MIR105-1,RC3H2,ANXA7,ZNF668,ZNF32,NGDN,HOXB1,GANAB,CXXC1,APOBEC3F,EHD3,SHMT1,DCLRE1C,LSM14B,SLU7,TCF21,RUVBL2,THAP8,TFRC,SUGP1,ZFP64,TWIST2,ZNF574,POLR3B,APOBEC3D,IRF3,CREBL2,MIR31,FAU,MRPS26,TOP1,SATB1,PREB,CIRBP,SMAD4,DIS3L,RRP7A,OGG1,MIR454,GATAD1,CTU1,CREB3L4,TWNK,RBM41,EDF1,PGBD2,MYC,MIR98,FOXC2,POLR1H,API5,PIAS1,MIR548C,MXD1,KPNA2,YWHAG,MSH6,AUH,MAPRE1,ATP5F1A,ZMYM4,SF3B6,ZNF790,OTX2,ZC3H14,MIR34B,FCF1,ORC5,RPL18,RPN1,THOC2,MIR30D,RBM23,HDAC3,POLD2,ACAA2,MIR1277,OVOL1,STXBP1,FOXP4,AGGF1,MIR152,SMAD1,PPARA,MAF1,MIR139,APOBEC3A,ZNF22,FERD3L,RAD1,PAX9,NQO1,TAF7,TEX19,TMSB4X,ZNF581,DDX1,MIR132,MIR25,POGK,ZNF436,MTDH,ZCCHC17,RNF40,MSL2,GTF2B,NOTCH2,MIR133B,MIR186,ZNF526,DNASE1L1,EIF2B2,CHCHD1,RFC3,TOPORS,MYRF,DMTF1,RBM18,NOP16,IER2,MIR200C,IREB2,ERCC3,ZBTB26,MIR29C,MIR130B,SMNDC1,CNOT6,RNASE4,CWC15,POP7,DDX50,MIR135B,ZNF692,H2BC17,YTHDF2,SP2,GTF3C4,CFAP20,SRSF7,RARS1,ZNF507,RPL6,MSX1,MRPL20,MIR200A,ZNF596,DDX23,THOC3,KLF9,HDAC5,DBR1,H2BW1,MIR920,TXN,MEF2A,GFM1,MIR32,SLPI,HSPA8,EXOSC3,RPS17,MLF1,BST2,MIR24-1,RPL26L1,ZNF24,UPF3B,NAA15,CCDC47,MIR188,RTF2,MIR193A,SRSF2,PRMT5,DKC1,CCAR1,MIR218-1,POLDIP3,MIR939,CEBPG,MXI1,IMP3,SSBP3,MIR373,BAHD1,FOXN2,XPO5,RPL7L1,SMYD3,TRUB1,GTF2H4,BRCA1,CREB3,ZMAT2,FBXL19,GTF2F2,DDX46,XPO1,C1D,RERE,MIR33B,MIR155,SSBP2,NOC4L,TLR8,H2AC13,EXD2,POLE3,HEXIM1,RNF10,TUBA1B,ISG20,NR1I2,MEPCE,MIR625,SMAD5,HNRNPA1,LSM14A,MIR195,PPP5C,EXOSC4,CSRNP1,IRF6,MIR301B,NR2F6,SOCS3,NOP53,RPL12,LRWD1,TAF10,MIR204,TCEA1,HSPE1,SRP54,CNP,SOX21,BRAP,POLR2C,SRFBP1,AIFM1,ZBTB45,EGR2,STAT6,MIR448,NOL4,SNRPD3,STAT2,NUDT1,ENDOD1,CBFB,EIF2D,PRPF4,MIR769,SP4,CXXC5,TFIP11,HMX1 |
| 1.393e-02 | -4.27 | ADGRL2 (adhesion G protein-coupled receptor L2) | protein interactions | 23266 | 77 | 31 | 19454 | 5460 |
CDC42,RND2,OTULINL,DNAJC25,ARL15,RND3,IRF3,RHOU,NTRK2,KRAS,EPHA4,FLOT1,STX7,RAB2A,DNAJC5,RHOB,NCK1,RHOG,LAMTOR1,STYK1,LMBR1L,RAB35,CCNF,RAC2,GJA1,RHOJ,RHOH,ARF6,CAV1,STX6,DIRAS3 |
| 1.393e-02 | -4.27 | FCHO2 (FCH and mu domain containing endocytic adaptor 2) | protein interactions | 115548 | 77 | 31 | 19454 | 5460 |
HRAS,RAB35,CCNF,LDLR,RAC2,GJA1,AP2M1,RHOJ,ARF6,DIRAS3,LAMP2,ATG9A,XPO1,LAMP3,MYO6,BICD2,RHOB,RHOG,LAMTOR1,NTRK3,RHOU,IGF1R,KRAS,EPHA4,RIGI,STX7,CDC42,FGFR1,CAPZA2,PICALM,AP2S1 |
| 1.393e-02 | -4.27 | LITAF (lipopolysaccharide induced TNF factor) | protein interactions | 9516 | 77 | 31 | 19454 | 5460 |
UBA52,NCALD,HPCAL1,BCS1L,WWP1,FGFR1,SDCBP,HGS,STAT6,TAB2,LRP10,BMPR1A,TOM1,LITAF,BCL6,RPS27A,WWP2,CDIP1,CARS1,BAG3,TTC33,REEP6,SMAD2,RNF208,COMT,OPTN,ACOX1,CACNB3,TSG101,TAX1BP1,UBB |
| 1.395e-02 | -4.27 | WFS1 (wolframin ER transmembrane glycoprotein) | protein interactions | 7466 | 98 | 38 | 19454 | 5460 |
TSPAN15,SYVN1,PSMA5,PXMP2,ARMCX2,RAF1,CCDC47,TMEM231,TP53,NDUFA2,ADIPOR1,OTULINL,DNAJC25,YIPF3,SEC62,MGARP,RPN1,SSR1,CD274,LMBR1L,NDUFB4,SYNGR1,TNFRSF9,HSD17B11,GPR173,STARD3NL,DNAJC1,CHCHD3,SMURF1,RAMP3,VIRMA,ESR2,SEC63,AKT1,EDEM1,GPR17,SMAD4,TYROBP |
| 1.395e-02 | -4.27 | MTMR1 (myotubularin related protein 1) | protein interactions | 8776 | 98 | 38 | 19454 | 5460 |
NDUFB10,DNAJC5,GMNN,CSNK2A1,RHOB,FBXW11,RHOG,HRAS,PTK7,RAB35,RAC2,PRNP,RHOH,ACTB,RHOJ,CAV1,NAA11,ZNHIT1,PI15,HCST,RND2,IGFBP3,CDC42,RAB6B,FEM1A,PNMA2,SCHIP1,RND3,MTMR2,FOS,TRIM10,RHOU,BAP1,EFNB1,CRYL1,SLC31A1,KRAS,FTL |
| 1.397e-02 | -4.27 | Sec61 complex | KEGG pathways | hsa_M00401 | 4 | 4 | 7161 | 2463 |
SEC61B,SEC61G,SEC61A1,SEC61A2 |
| 1.397e-02 | -4.27 | Sec61 complex | KEGG pathways | M00401 | 4 | 4 | 7161 | 2463 |
SEC61B,SEC61G,SEC61A1,SEC61A2 |
| 1.399e-02 | -4.27 | S100A4 (S100 calcium binding protein A4) | protein interactions | 6275 | 141 | 52 | 19454 | 5460 |
VPS39,BTF3,TXNIP,SMAD2,DNAJB6,S100A6,PHF12,ZBTB33,METAP2,RCBTB1,MATR3,DYNLL1,UMPS,SRPK2,CCN3,PATE2,TOM1L2,SEPTIN6,PEBP1,RHOU,MYH2,RAB5A,OIP5,MOV10,HDAC6,PPFIBP1,SUV39H1,TPM3,CRBN,IFNB1,VCPIP1,HSPB1,SMAD3,IGBP1,SPPL3,MDM2,MYL12A,HSBP1,RAF1,SPC24,TP53,ESS2,H2AX,CHMP4C,S100B,SEPTIN7,UBE3A,ZBED1,TNF,PSMA1,SATB1,SSNA1 |
| 1.399e-02 | -4.27 | MAEA (macrophage erythroblast attacher, E3 ubiquitin ligase) | protein interactions | 10296 | 141 | 52 | 19454 | 5460 |
FLOT1,RIGI,LECT2,TRIM37,S100A10,MKLN1,MAEA,HBP1,NDUFS6,UCK2,ADAMTS1,SOX2,EMILIN3,TULP3,RAF1,TOP3B,GPT,LY6H,JPH4,EGLN3,HNRNPL,LILRB4,DUSP6,ARMC8,MRPL18,TCEAL9,TMEM70,IL17F,INSYN1,CTNNB1,SPON1,DDX50,TLE1,RANBP10,UBE2D3,GREM2,DDX5,RMND5B,LCA5,GID4,DVL2,GID8,BMP1,GSK3A,YPEL5,NAPA,UBE2H,RIT1,HTRA2,FAS,CUL3,MRM2 |
| 1.399e-02 | -4.27 | TMEM214 (transmembrane protein 214) | protein interactions | 54867 | 141 | 52 | 19454 | 5460 |
CSGALNACT1,TMEM179B,LMNB1,HMOX2,DNAJC5,CSGALNACT2,SEC63,LYPD6,SEC61B,RMDN3,DPEP1,LMBR1L,RBM18,SSR1,LMNA,RPA2,ST7,SEC62,CDC42,OTULINL,FAM234A,PXMP2,GPC1,DERL1,TLR2,RPA3,UPK1A,TLR10,SLC25A46,NUP35,TLR1,TMPO,DNAJC1,RAC2,SPINT2,HSD17B11,PTPN1,KCNA2,RPRM,SEMA7A,CRELD1,RPN1,ZC4H2,STIM1,NUP153,CCDC47,DPM2,FKBP8,KRAS,NUP107,TMT1A,RUSF1 |
| 1.400e-02 | -4.27 | positive regulation of kinase activity | biological process | GO:0033674 | 302 | 107 | 18204 | 5365 |
EPHA4,TLR3,TCIM,IL12B,TAB2,IFNG,CCNY,CCL5,DIPK2A,PPIA,CD86,DUSP19,CACUL1,ERP29,FERMT2,IGF1R,TOM1L1,PTPN1,SRC,GHR,TPD52L1,ANGPT1,FGFR1,PSRC1,MIR26B,PIK3CG,TLR4,LEP,DLG4,PRNP,PHB2,MAP3K12,HSP90AA1,TAB1,IL34,DSTYK,PRKAG1,EZH2,IL23A,HSP90AB1,AGAP2,IL4,RGCC,EMP2,CD4,MIR21,CAMK1,NBN,NTRK3,NTRK2,LCP2,TGFB2,MAP2K3,IGF1,MAP3K11,ADIPOQ,TNF,PDCD10,MT3,CCND3,PHB1,RPS3,GH1,TXN,RAP1A,TRAF2,AKT1,RALB,EPHA2,TNFSF15,IL1B,CD40,STK11,PROX1,HRAS,ADRB2,FBXW7,CAB39,TLR6,CCR7,FGF1,CDKN1A,ZNF622,PSMD10,JAK2,CHI3L1,MMD,BAD,FCGR1A,STRADB,DVL2,MAP2K1,PIH1D1,TRAF6,KIT,LMO4,DDR1,MET,DIRAS2,CARTPT,XRCC5,DLG3,CCND1,CCL19,DIRAS1,F2,TGFBR2 |
| 1.401e-02 | -4.27 | MPP7 (MAGUK p55 scaffold protein 7) | protein interactions | 143098 | 95 | 37 | 19454 | 5460 |
RHOJ,RHOH,ARF6,CAV1,HSBP1,DUSP10,STX6,DIRAS3,EEF1AKMT3,RAB35,HRAS,RAC2,DLGAP4,GJA1,RHOB,RHOG,LAMTOR1,NTRK3,RAB11A,LIN7B,RAB2A,DNAJC5,KRAS,PTPN4,SLC31A1,FLOT1,STX7,RHOU,LIN7C,EFNB1,TRIM5,FGFR1,ADAMTS1,MTMR2,RND3,CDC42,RND2 |
| 1.401e-02 | -4.27 | PNPLA6 (patatin like phospholipase domain containing 6) | protein interactions | 10908 | 95 | 37 | 19454 | 5460 |
TEX264,CXCR4,TSPAN17,VIPR1,KRAS,HSCB,LRP3,FBXW7,UBE2A,TOP3B,HCST,FAF2,FAXC,CTLA4,SDC2,STIM1,PLD3,LMBR1L,CD79B,COQ8A,CCNF,HNRNPL,DNAJC1,EGLN3,CLRN2,NUP35,ESR2,MYC,MOV10,CUL3,LRRTM1,GPRASP2,PPIB,HFE,PDCD1,BAX,ILK |
| 1.401e-02 | -4.27 | MAP2 (microtubule associated protein 2) | protein interactions | 4133 | 80 | 32 | 19454 | 5460 |
HNRNPA0,GPM6A,RPL23A,DHX9,ABCF1,TRIM36,NEFL,DDX39A,TUBA1A,MSX2,PAFAH1B1,MDM2,JUNB,SRC,HNRNPL,FBXO22,ACTB,DYNC1I2,GSK3A,PSMC5,EIF3K,ARMC1,HAX1,MAPRE1,YWHAB,YWHAZ,CPEB1,YWHAH,YWHAG,PRKACB,DAG1,SFN |
| 1.401e-02 | -4.27 | QPCTL (glutaminyl-peptide cyclotransferase like) | protein interactions | 54814 | 80 | 32 | 19454 | 5460 |
UBE2H,NTRK3,RC3H2,DDRGK1,FAM20C,CUL3,MYC,NFKB1,SEC63,MAD2L2,ESR2,FBXO22,FZR1,COPE,OCRL,PTEN,DUSP6,LMBR1L,CCNF,RNF8,CAMK1,CDK7,FAM13B,E2F4,FBP1,RAF1,RNF11,CHN2,UFL1,DCP2,CDKN2C,FAF1 |
| 1.401e-02 | -4.27 | ACD (ACD shelterin complex subunit and telomerase recruitment factor) | protein interactions | 65057 | 80 | 32 | 19454 | 5460 |
NCDN,HSPA8,HAPSTR1,FBXW7,TRIM63,LASP1,MDC1,RPSA,TUBB4B,ZNF790,EIF4B,CTTN,ENO2,STUB1,RB1,TRIM15,AIPL1,ACTB,LDHA,AFAP1L2,HSP90AB1,EGLN3,ANKMY2,APOBEC3F,BAG3,GAPDH,NTAQ1,XPO1,BRCA1,ADPRH,CKB,EIF3G |
| 1.401e-02 | -4.27 | G1/S transition of mitotic cell cycle | biological process | GO:0000082 | 68 | 29 | 18204 | 5365 |
CDK4,CDK6,CCNA2,CDKN3,PIAS1,HINFP,CCND1,BTN2A2,HSPA8,CDK1,ACVR1B,RHOU,PPP3CA,CDKN1B,CDC7,CUL3,EZH2,CCND3,RB1,ID4,EIF4E,CACUL1,PIM2,MYC,CDKN1A,TAF10,RBBP8,MNAT1,CUL2 |
| 1.405e-02 | -4.27 | CAMK1 (calcium/calmodulin dependent protein kinase I) | protein interactions | 8536 | 92 | 36 | 19454 | 5460 |
CCND1,CDK4,COMTD1,CER1,CAMK1,PPME1,BCKDK,CCDC106,ACTR1B,HDAC5,SRSF2,PSMA5,PSMD12,CUL3,PIK3R3,GPR17,ST6GALNAC3,CDO1,CSK,QPCTL,ATF1,GAPDH,P2RY10,FBXO7,SMCHD1,PSMD14,AK2,HSPB1,UBE2H,CDKN1B,EEF1AKMT3,CCNF,PSMD6,SNRPB2,DKC1,TMPO |
| 1.405e-02 | -4.27 | AHSG (alpha 2-HS glycoprotein) | protein interactions | 197 | 92 | 36 | 19454 | 5460 |
DPP4,CSK,RAB11A,RPS6KA4,HSP90AA1,UBE2H,STYK1,FOLR1,RRAS2,ALB,TRIM24,KCTD15,SUMO2,LGALS3,RHOH,PPP5C,ESR2,USP38,TOP3B,CA8,SOX2,RND2,CDC42,CFTR,EZH2,CCR1,CAV2,FURIN,RNF8,SOD1,CDK5,PSMA3,H3C1,EPHA4,TNF,FBXW7 |
| 1.405e-02 | -4.27 | RIC8A (RIC8 guanine nucleotide exchange factor A) | protein interactions | 60626 | 92 | 36 | 19454 | 5460 |
PDE4B,ATG7,XPO1,MYC,STK11,SKIC8,GNAO1,RMDN3,LDLR,PAPSS2,LMBR1L,GNAI2,APEX1,PRNP,ACTR1A,ARFGAP1,TOP3B,SH3GLB1,GNAQ,GNAZ,GNAI3,SDCBP,RPA2,VAPB,DCTN4,HBB,RABAC1,EP300,ACTR1B,DCTN3,RPA3,GNA11,DCTN6,PYGB,ZDHHC17,FBXW7 |
| 1.405e-02 | -4.26 | NEXN (nexilin F-actin binding protein) | protein interactions | 91624 | 83 | 33 | 19454 | 5460 |
CAPZA2,DISC1,TMOD1,WDR77,CRYGD,UBA52,PPP1CB,LGR4,FXR2,KRAS,G3BP1,HMGB1,TRIM37,MYO1B,HSPA8,SLC39A3,FBXO34,FAM107A,RPL23,HSPB1,MAPRE1,VMP1,ZNF250,MYC,HDAC6,DAPK1,TRIM15,ACTB,VIRMA,ACTA2,CTTN,NXT1,TES |
| 1.405e-02 | -4.26 | PGR (progesterone receptor) | protein interactions | 5241 | 83 | 33 | 19454 | 5460 |
SMARCE1,CSNK2A1,COPS5,SPOP,NR0B1,FKBP4,BRCA1,HSP90AA1,SP1,DNAJC7,HERC4,STUB1,APEX2,SGTA,TRIM24,POLR3H,PGR,STAT5A,ZBTB17,PPP5C,HSP90AB1,KLF9,SRC,ANP32A,PRMT2,CCNA2,RBM23,XRCC5,UBE3A,EP300,HDAC3,HMGB1,PIAS1 |
| 1.405e-02 | -4.26 | CDCA7L (cell division cycle associated 7 like) | protein interactions | 55536 | 83 | 33 | 19454 | 5460 |
RRP7A,ZDHHC15,SSX2IP,NOL12,PPP1R16A,CEP70,SUV39H1,PRPF31,GPRASP3,TM9SF4,NDUFB7,ZNF250,MYC,MDFI,EIF4A3,TRAF3IP3,S100A6,AVPI1,PIH1D1,MFAP1,DMAP1,TNNI1,EZH2,ING5,UBL4A,VDR,STX11,CDCA7L,ZNF821,SNRNP48,CTNNBL1,PICK1,TFPT |
| 1.405e-02 | -4.26 | SORD (sorbitol dehydrogenase) | protein interactions | 6652 | 83 | 33 | 19454 | 5460 |
TOLLIP,ETFA,GPC1,TCEA1,RPA3,SOD1,FURIN,NME1,LDHAL6B,PLS3,RPA2,CRYAB,PGM1,DDX39A,METTL26,CAV1,NUP35,KLF9,FAH,BCCIP,MYG1,PRKCE,LDHA,FAHD1,AKR1B1,SORD,NRP1,PFDN4,AGR2,CHORDC1,SMAD4,LDHB,MYC |
| 1.405e-02 | -4.26 | MIR31 (microRNA 31) | protein interactions | 407035 | 83 | 33 | 19454 | 5460 |
G3BP2,MARS1,HNRNPK,HNRNPA0,TRA2B,HNRNPF,RTCB,SF3B1,HNRNPH2,HNRNPA2B1,NUFIP2,RARS1,HNRNPH3,RBFOX2,STRBP,SF3A1,CDC5L,FAM98A,HNRNPL,MATR3,SF3B4,MYEF2,EIF2AK2,SYNCRIP,CPSF1,IGF2BP1,DDX1,NONO,TRA2A,HNRNPA1,APOBEC3B,KARS1,GRSF1 |
| 1.405e-02 | -4.26 | MIR200B (microRNA 200b) | protein interactions | 406984 | 83 | 33 | 19454 | 5460 |
HNRNPH2,SF3B1,RTCB,HNRNPA2B1,G3BP2,MARS1,HNRNPF,TRA2B,HNRNPA0,HNRNPK,STRBP,SF3A1,RBFOX2,HNRNPH3,RARS1,SART3,SF3B4,SYNCRIP,EIF2AK2,CDC5L,MATR3,HNRNPL,FAM98A,HNRNPA1,NONO,TRA2A,KARS1,GRSF1,APOBEC3B,DDX1,IGF2BP1,DDX23,CRTAP |
| 1.405e-02 | -4.26 | R3HDM1 (R3H domain containing 1) | protein interactions | 23518 | 83 | 33 | 19454 | 5460 |
LSM14A,PABPC1,BAG2,AKAP1,EWSR1,ZC3H7A,STAU1,YTHDF1,LITAF,G3BP1,YTHDF2,PRMT2,LARP4B,FBLN5,SMAP2,FUBP3,SYNCRIP,PRRC2A,EGLN3,MOV10,CSK,MYC,YWHAH,CPEB1,NTAQ1,TIA1,YWHAG,XPO1,DCAF4,YWHAZ,UBE2H,YWHAB,IGF2BP1 |
| 1.405e-02 | -4.26 | MBD5 (methyl-CpG binding domain protein 5) | protein interactions | 55777 | 83 | 33 | 19454 | 5460 |
VIRMA,CCT7,MAT2B,CBX5,DYNLL1,PRNP,SNRPA1,LYAR,SNX3,SNRPD3,HNRNPL,TXN,HP1BP3,EIF2S2,SRSF1,H1-10,H2BC9,HMGCS1,FBXO7,CFL1,DPY30,NAA50,SKP1,KPNA2,H3C1,DDX5,SLC25A5,BAP1,JUP,ETF1,CCT5,TOP3B,NAA15 |
| 1.405e-02 | -4.26 | NT5E (5'-nucleotidase ecto) | protein interactions | 4907 | 83 | 33 | 19454 | 5460 |
KCTD10,ACTB,ESR2,GJA1,RHOG,DEGS1,MYC,SYNJ2BP,RAB11A,USP3,SLC41A1,CTNNB1,SLC30A5,TMEM177,TNFSF8,CAMKV,TRIM37,SLC6A8,SAR1B,RFC2,HSDL1,CXCR4,ARG2,HAPSTR1,RAB9A,PLAA,GHITM,NUPR1,ADIPOR1,NDUFA2,TMEM106A,SOX2,TNPO2 |
| 1.405e-02 | -4.26 | STON2 (stonin 2) | protein interactions | 85439 | 83 | 33 | 19454 | 5460 |
KRAS,HSPA5,COPS4,STX7,RHOU,DVL2,EP300,CCDC32,NMRAL1,CAPZA2,PICALM,MOB3C,AP2S1,RAF1,TOMM22,CDC42,PPP1CB,RHOJ,ESR2,VIRMA,VDAC2,RAC2,SYT2,AP2M1,RHOB,LAMTOR1,RHOG,ZCCHC10,MYC,ATG9A,RACGAP1,TOMM40,HDAC6 |
| 1.405e-02 | -4.26 | EPHB6 (EPH receptor B6) | protein interactions | 2051 | 83 | 33 | 19454 | 5460 |
CPT2,VPS26C,LANCL1,HSP90AB1,AIP,WDR6,CDCA3,S100A8,PRMT5,NCK1,NIF3L1,HSP90AA1,CBL,EPHA2,MYC,PIK3R1,GORASP2,BCL6,DUSP19,ARF4,NDUFA4,RABAC1,SAT1,ATP5PO,CRKL,ARCN1,PGRMC1,DDIT4L,USP6NL,DUSP18,PABPC5,NTPCR,MSX2 |
| 1.406e-02 | -4.26 | genital_tract-extragonadal-germ_cell_tumour-mixed | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-mixed | 28 | 14 | 16828 | 4835 |
IKZF2,PTEN,DICER1,KDM2A,CTNNB1,MAP1B,MFAP3L,KIT,TP53,KRAS,HRAS,RPGRIP1L,IDH1,CBL |
| 1.406e-02 | -4.26 | endonuclease complex | cellular component | GO:1905348 | 41 | 19 | 19108 | 5553 |
DHX9,DGCR8,DICER1,TSNAX,RPP25L,TSN,PRKRA,AGO1,RPP25,POP7,HSD17B10,RPP14,POP5,CLP1,TSEN54,DROSHA,TSEN34,RAG1,RPP21 |
| 1.407e-02 | -4.26 | NDUFA3 (NADH:ubiquinone oxidoreductase subunit A3) | protein interactions | 4696 | 89 | 35 | 19454 | 5460 |
LMNB1,NDUFV2,TM4SF19,ESD,SLC7A8,TLCD4,NDUFAF4,CRB3,ATP5F1B,NDUFA1,CYB5R3,GSTP1,TMEM14B,NDUFS3,AQP3,NDUFS6,MGARP,CYB5R1,PRDX3,TMEM205,TIMMDC1,TMEM101,HSCB,DNAJC30,RER1,HAPSTR1,GNG5,ERG28,HADHA,GAL3ST1,NDUFC2,THBS3,TMX2,RAB1A,NDUFB5 |
| 1.408e-02 | -4.26 | PPP1R13L (protein phosphatase 1 regulatory subunit 13 like) | protein interactions | 10848 | 86 | 34 | 19454 | 5460 |
CCR1,STX17,MAGEA4,NFE2L2,JUN,PPP1CB,SOX2,CFTR,ATG16L1,WDR83,E2F4,TP53,GABBR1,HSPA8,BAG2,EP300,RNF113A,S100B,PML,SP1,MAPRE1,SMCHD1,XPO1,PPP1CC,TAX1BP3,CREBBP,NFKB1,CUL3,ATP6AP2,MAD2L2,ESR2,SRPK2,IRF2BP1,GSK3A |
| 1.408e-02 | -4.26 | NEMP1 (nuclear envelope integral membrane protein 1) | protein interactions | 23306 | 86 | 34 | 19454 | 5460 |
CUL3,CD81,TMEM42,FAXDC2,TMEM14A,METAP2,RAN,VAMP3,PTPN1,CCNF,LMBR1L,SEC61B,UBE2I,TMEM229B,CXCL9,NOP58,TMEM97,CLRN2,INSIG2,CCDC47,GLRB,SOX9,TMUB2,SSR1,SIGLECL1,PLD3,STX12,DYRK2,CLEC7A,ZYX,DERL1,KPNA2,ADIPOQ,B2M |
| 1.408e-02 | -4.26 | TBC1D2B (TBC1 domain family member 2B) | protein interactions | 23102 | 86 | 34 | 19454 | 5460 |
RFXANK,RND2,GABARAPL1,ATG16L1,PSMC3,PAK5,VPS33A,RAB4A,THBS3,MTDH,RAB5A,TRIM37,XPO1,CAV3,HSPB8,GSTM3,UBXN6,RAB11A,LAMTOR1,RHOG,RHOB,PPM1M,GJA1,NRSN1,MAP1LC3A,KRT8,RAB35,CRYBB3,S100A6,EEF1AKMT3,LURAP1,CIB2,NAA11,FBXO22 |
| 1.408e-02 | -4.26 | H2AC18 (H2A clustered histone 18) | protein interactions | 8337 | 86 | 34 | 19454 | 5460 |
DNM2,CTDSPL2,CDK9,NCKAP1,VIRMA,USP16,SNRNP40,RBBP4,HMGA1,PRMT6,CUL3,HNRNPD,CBL,UBE2H,ATG3,NCK1,RPS6KA4,RUVBL2,MAP1B,BAP1,PPM1G,RNF20,MEPCE,MSL2,G3BP1,NUCKS1,HMGB1,PAFAH1B1,HEXIM1,PDHA1,DNAJC2,NECAP1,PICALM,EMC9 |
| 1.410e-02 | -4.26 | GPROTEINBRPT | prints domains | PR00320 | 83 | 34 | 5227 | 1528 |
PRPF19,SNRNP40,SMU1,WDSUB1,DCAF11,WDR44,ATG16L1,POC1B,SKIC8,WDR5B,PAFAH1B1,FBXW7,BUB3,WDR3,WDR82,THOC3,PAK1IP1,GNB3,WSB1,RBBP7,PRPF4,NLE1,WDR83,GNB4,GNB1,FBXW11,WDR12,RBBP4,TRAF7,PWP2,WDR38,WDR37,TAF5L,PAAF1 |
| 1.413e-02 | -4.26 | ubiquitin protein ligase activity | molecular function | GO:0061630 | 350 | 124 | 18094 | 5411 |
MED21,UBE3A,UBE2D3,NOSIP,MED27,RNF128,TRIM63,RNF113A,TRIM23,RNF144B,RNF103,RING1,TRIM6,TRAF6,PRPF19,ASB1,RNF152,PPP1R11,UBE2K,MUL1,TOPORS,BFAR,RNF20,RNF40,MSL2,TRIM44,COP1,CUL3,RNF8,UBE2D1,HECTD1,TRIM37,TRIM62,TRIM11,TRIM34,HUWE1,RNF39,MED31,RNF133,GID4,RNF7,ZNRF1,TRIM8,CDC42,TRIM15,SHPRH,UBR7,HECW1,STUB1,TRIM27,TRIM10,HERC3,RNF14,MED30,FBXO30,SYVN1,RNF148,ANKIB1,TRIM45,TRIM32,TRAF3IP2,RNF181,TRIM24,PELI1,PCGF3,PELI3,IRF2BPL,RNF122,HERC4,IRF2BP1,MDM2,BRAP,WWP1,RNF34,SIAH2,MED10,TRIM21,TRIM52,RNF5,AREL1,TRIM22,TRAF7,RCHY1,MED17,TRIM54,RNF146,RNF121,TRIM68,NEURL2,RNF26,SMURF1,RMND5B,RNF139,TRIM3,CDK8,SIAH1,MED11,CBLL1,RLIM,WSB1,RNF126,WWP2,RNF41,FBXO44,MARCHF5,RNF10,TRIM35,RNF11,RC3H2,ANAPC11,TRIM5,RAG1,RNF208,RNF167,RNF115,CCAR1,BIRC2,CBL,NT5C2,UBE2A,MYLIP,VPS18,MAEA,TRIM26 |
| 1.413e-02 | -4.26 | F2R (coagulation factor II thrombin receptor) | protein interactions | 2149 | 34 | 16 | 19454 | 5460 |
CAPN1,F2,TAB2,GNAQ,FURIN,ARRDC3,CXCL14,ITGAV,CAV1,GNAI2,PLG,TAB1,ARMC6,CRYL1,GRPR,SNX1 |
| 1.413e-02 | -4.26 | SLC31A2 (solute carrier family 31 member 2) | protein interactions | 1318 | 34 | 16 | 19454 | 5460 |
CSK,ENDOD1,PTRH2,SIGMAR1,GPR35,RIT1,H1-1,PLSCR1,SLC1A1,SLC31A1,SLC20A2,SLC6A8,RAMP3,CAV1,OPRL1,ACP2 |
| 1.413e-02 | -4.26 | STRIP2 (striatin interacting protein 2) | protein interactions | 57464 | 34 | 16 | 19454 | 5460 |
FAM136A,PDCD10,STK24,PPP2R1A,FGFR1OP2,SUPT5H,CTTNBP2NL,SLMAP,CYTH2,SPPL3,DYNLL1,STK26,CTTNBP2,PPP2CB,TRAF3IP3,SIKE1 |
| 1.413e-02 | -4.26 | SETD5 (SET domain containing 5) | protein interactions | 55209 | 34 | 16 | 19454 | 5460 |
DPPA2,HNRNPL,VRK1,LDOC1,FTL,RIGI,SSRP1,FBLN5,RMND5B,BRD3,TOP3B,SUPT5H,PRMT2,TRAF2,CEP70,CCDC85B |
| 1.413e-02 | -4.26 | KCTD21 (potassium channel tetramerization domain containing 21) | protein interactions | 283219 | 34 | 16 | 19454 | 5460 |
SEC61A1,LSM12,ATP1A2,KCTD15,UFM1,CEP97,MAD2L1,CUL3,TNFAIP6,ZMYND19,DUSP22,SOX2,NTAQ1,DDX39A,CRLF3,NMRK1 |
| 1.413e-02 | -4.26 | RAB38 (RAB38, member RAS oncogene family) | protein interactions | 23682 | 34 | 16 | 19454 | 5460 |
SMAD3,NPTN,APLNR,RIGI,RAB32,BMPR1B,RAF1,C9orf72,ICAM2,LAMP3,SMAD1,EZH2,SMAD4,AQP3,SMAD2,AGPAT1 |
| 1.413e-02 | -4.26 | HPS6 (HPS6 biogenesis of lysosomal organelles complex 2 subunit 3) | protein interactions | 79803 | 34 | 16 | 19454 | 5460 |
OSGEP,METTL14,AR,CNP,XPO1,TOP3B,VIRMA,ESR2,MNAT1,TUSC2,EGLN3,SUMO2,EP300,HSPA8,CCNF,CREB1 |
| 1.413e-02 | -4.26 | SOST (sclerostin) | protein interactions | 50964 | 34 | 16 | 19454 | 5460 |
SPOP,DCAF5,PSMG2,PSMG3,AP2A1,LRP6,PRMT6,KCTD10,PLEKHF2,GTF2I,USP16,CMAS,AHCYL1,TNKS2,PPP1R12A,TNKS |
| 1.415e-02 | -4.26 | astrocytoma | COSMIC cancer mutations | astrocytoma | 36 | 17 | 16828 | 4835 |
KRAS,HRAS,IDH1,SF3B1,TP53,CTNNB1,KIT,IDH2,NF2,AKT1,CDKN2C,PTPN11,PIK3CA,TERT,ACVR1,PTEN,SMARCB1 |
| 1.415e-02 | -4.26 | carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | carcinosarcoma-malignant_mesodermal_mixed_tumour | 36 | 17 | 16828 | 4835 |
SF3B1,SMAD4,KRAS,PTEN,SMARCB1,DICER1,PIK3CA,JAK2,NF2,AKT1,PPP2R1A,KIT,RB1,MET,CTNNB1,BRCA1,TP53 |
| 1.417e-02 | -4.26 | AGE-RAGE signaling pathway in diabetic complications | KEGG pathways | hsa04933 | 99 | 45 | 7161 | 2463 |
TGFBR2,PRKCB,STAT5A,NFKB1,AKT3,STAT1,AKT2,VEGFC,JUN,CDK4,TNF,COL1A2,CDKN1B,PIK3CA,CCL2,SMAD2,IL1A,IL1B,IL6,BAX,PIK3R3,PRKCA,EGR1,AKT1,JAK2,SMAD3,THBD,PLCB2,PIK3R2,CDC42,KRAS,PIK3R1,TGFB3,TGFB2,CXCL8,CCND1,VEGFA,COL3A1,ICAM1,MAPK10,AGER,HRAS,SMAD4,PRKCE,PLCB1 |
| 1.417e-02 | -4.26 | AGE-RAGE signaling pathway in diabetic complications | KEGG pathways | ko04933 | 99 | 45 | 7161 | 2463 |
PRKCB,STAT5A,CDK4,STAT1,VEGFC,AKT2,JUN,IL1B,BAX,TNF,PIK3CA,CCL2,PIK3R3,CDC42,PIK3R2,AKT1,SMAD3,JAK2,PLCB2,PIK3R1,TGFB3,KRAS,COL3A1,MAPK10,CCND1,PRKCE,PLCB1,AGER,AKT3,TGFBR2,NFKB1,IL1A,IL6,CDKN1B,COL1A2,SMAD2,PRKCA,EGR1,THBD,TGFB2,VEGFA,ICAM1,CXCL8,HRAS,SMAD4 |
| 1.417e-02 | -4.26 | The Oncogenic Action of Succinate | SMPDB pathways | SMP0002292 | 30 | 18 | 1369 | 531 |
SDHB,DLST,IDH3B,IDH1,IDH3A,PDHB,EGLN3,IDH2,SUCLG2,ACO1,SDHC,PC,SLC25A10,MPC1,KDM2A,EGLN2,ACO2,DLAT |
| 1.417e-02 | -4.26 | The Oncogenic Action of Fumarate | SMPDB pathways | SMP0002295 | 30 | 18 | 1369 | 531 |
KDM2A,EGLN2,DLAT,ACO2,PC,SLC25A10,MPC1,IDH2,SUCLG2,ACO1,SDHC,SDHB,IDH1,IDH3B,DLST,IDH3A,PDHB,EGLN3 |
| 1.418e-02 | -4.26 | hydrolase activity, hydrolyzing N-glycosyl compounds | molecular function | GO:0016799 | 40 | 19 | 18094 | 5411 |
PCNA,MPG,TLR2,SMUG1,SARM1,DCTD,OARD1,TLR1,MACROD1,IL1RAP,APEX1,OGG1,DNPH1,TLR4,RPS3,CD38,TLR10,TLR6,ADPRH |
| 1.421e-02 | -4.25 | FUT8 (fucosyltransferase 8) | protein interactions | 2530 | 138 | 51 | 19454 | 5460 |
NRSN1,TNFSF18,RAB1B,OS9,DHX15,RAMP3,SLC25A17,FAM174A,ICAM2,RAB5C,CD200R1,CCR6,HNRNPD,STX8,RAB1A,ICAM3,TMX3,BSCL2,STX18,LPAR2,PDE2A,FGL2,RELL2,CTLA4,TRAPPC13,LMBR1L,S1PR4,TMEM74,B3GALNT1,MGAT1,ESR2,NPTX1,KDSR,SLC30A5,FBXO7,CSGALNACT2,TSPAN15,RPL27,RPA3,DNAJC3,SYVN1,CLEC12B,HSPA5,ITGAV,PDCD1LG2,CCL3,SEC62,TMEM106A,CTBP1,RPA2,CHRNB2 |
| 1.426e-02 | -4.25 | positive regulation of amide metabolic process | biological process | GO:0034250 | 30 | 15 | 18204 | 5365 |
SP1,CSNK1E,GSK3A,PICALM,IFNGR1,CHRNA7,LRRTM3,CLU,TNF,NFE2L2,SPHK2,EPHA4,MIR206,ROCK2,IFNG |
| 1.426e-02 | -4.25 | neurotransmitter uptake | biological process | GO:0001504 | 30 | 15 | 18204 | 5365 |
SLC38A1,SLC6A2,SLC29A1,SLC1A2,SLC6A11,ATP1A2,SLC1A3,SNAP25,CLN8,SLC6A3,SLC6A4,SLC18B1,SLC6A1,KCNJ10,SLC6A12 |
| 1.426e-02 | -4.25 | negative regulation of steroid biosynthetic process | biological process | GO:0010894 | 30 | 15 | 18204 | 5365 |
GFI1,NR0B1,ERLIN2,MIR342,CYP27B1,MIR185,NFKB1,ATP1A1,MIR98,ERLIN1,SNAI2,DKK3,INSIG2,PROX1,SOD1 |
| 1.427e-02 | -4.25 | FANCA (FA complementation group A) | protein interactions | 2175 | 163 | 59 | 19454 | 5460 |
PCNA,FANCG,PSMA5,KRAS,TOP3B,RBPJ,TAF10,RPL18,AZIN1,FAAP100,EEF1AKMT3,HSP90AB1,SPTAN1,TCP1,P2RY10,COMMD5,CTNNB1,UBXN6,ZNF24,MGMT,VCPIP1,IKBKB,TUBG1,TRAF6,DUS4L,HSPA8,DDIT3,SMARCD3,DDX39B,CXCR4,NF2,NPTN,HCST,NEK2,RFXANK,MX1,NPY2R,CAPN1,TPT1,RPA2,CDK1,CTBP1,HSP90B1,LMBR1L,ENO1,NFKBIB,CHRM4,APLNR,ATP5F1B,PRPF31,RMI2,AKT1,OPRM1,GPR17,HSP90AA1,STK11,SNX5,RMI1,BRCA1 |
| 1.427e-02 | -4.25 | MORF4L2 (mortality factor 4 like 2) | protein interactions | 9643 | 163 | 59 | 19454 | 5460 |
PHF12,VPS72,TAB1,ACTB,TSN,MYC,MORF4L1,KPNA6,BRCA1,H2AZ2,EXOSC1,GRAMD2B,RPA3,SQSTM1,FBXW7,TNNT2,KLHL3,DDIT4L,ACTL6A,MRPL12,VAPB,RPA2,LMNA,CDR2,HEXIM1,PITPNA,H2AZ1,SYNCRIP,SIN3A,MPDU1,PHB1,RB1,GATAD1,FZR1,MEAF6,IFI16,TLE1,NAB2,KPNA1,RBP2,MRFAP1L1,RUVBL2,PICK1,MRFAP1,SYN3,RBBP7,HNRNPK,ZBTB14,KPNA2,RUVBL1,MAX,TUBA1A,THAP1,DMAP1,EZH2,PNMA2,H2BC1,DISC1,ZBTB26 |
| 1.430e-02 | -4.25 | midbrain | COSMIC cancer mutations | midbrain | 47 | 21 | 16828 | 4835 |
PIK3CA,XAF1,FGFR1,SMARCB1,TP53,SLCO1B3,CTNNB1,MET,KIT,GNA11,PPP2R1A,FBXW7,IDH2,PARM1,AKT1,ETV6,GNAQ,KRAS,LGI1,SNRNP48,IDH1 |
| 1.431e-02 | -4.25 | KIAA1191 (KIAA1191) | protein interactions | 57179 | 48 | 21 | 19454 | 5460 |
RAP1B,CLPB,GSK3A,HSPA8,SFXN1,RHOU,AIFM1,APEX1,COX14,MSH6,PLGRKT,SLC25A12,VPS16,PRNP,HUWE1,PPP1CC,XPO1,YWHAH,MAPRE1,NOL12,BICD2 |
| 1.431e-02 | -4.25 | IL3RA (interleukin 3 receptor subunit alpha) | protein interactions | 3563 | 48 | 21 | 19454 | 5460 |
CDK1,NCR3LG1,SYS1,FGFR1,C2CD2L,GPBP1L1,MARCHF3,FOXP1,VAMP5,PPP1CC,CISH,STX7,JAK2,CSF2,IL3,JAGN1,SLC22A6,JAK1,TMEM254,EMP3,TMEM147 |
| 1.431e-02 | -4.25 | UQCC2 (ubiquinol-cytochrome c reductase complex assembly factor 2) | protein interactions | 84300 | 48 | 21 | 19454 | 5460 |
MRPS18C,CHCHD2,SNAP25,CEACAM5,YBEY,MRFAP1,COX20,TMEM185A,CXCR4,NDUFA4,EXOC8,CDR2,SLX1A,HSPB1,P3H1,NRDE2,TM2D2,GNG13,CDKN2D,TPT1,PMPCA |
| 1.431e-02 | -4.25 | N4BP3 (NEDD4 binding protein 3) | protein interactions | 23138 | 48 | 21 | 19454 | 5460 |
MAVS,CNKSR3,RIGI,RNF41,ENKD1,DYNLL1,SPG21,LMO4,CTDSP2,XPO1,RFC5,YWHAG,NTAQ1,YWHAH,SFN,YWHAB,YWHAZ,PNMA2,CAPZA2,BPNT2,SDCBP |
| 1.431e-02 | -4.25 | PCBD2 (pterin-4 alpha-carbinolamine dehydratase 2) | protein interactions | 84105 | 48 | 21 | 19454 | 5460 |
AATF,CDC5L,DBT,KCNIP3,IRF2BP1,C1D,TAL2,MRFAP1,PML,METAP2,MET,MED4,GUCD1,MED21,SPG21,XBP1,PCBD1,MED30,GTF2E1,FBXO7,HNF1B |
| 1.431e-02 | -4.25 | TTC33 (tetratricopeptide repeat domain 33) | protein interactions | 23548 | 48 | 21 | 19454 | 5460 |
SNRPB,SF3A1,PFDN5,CDC73,BMERB1,PFDN4,SF3B5,PFDN6,SKIC8,SNRPD2,SF3B4,SF3B1,PLPPR1,PSMB1,KRT8,SF3B6,PPP2CB,ORMDL1,SNRPB2,KDM1A,LITAF |
| 1.431e-02 | -4.25 | IQCF1 (IQ motif containing F1) | protein interactions | 132141 | 48 | 21 | 19454 | 5460 |
FAM118B,BPGM,LZTFL1,EHD4,EIF2AK2,TFIP11,SERPINB1,EPHX1,PAXX,TBC1D4,GTPBP2,MCM8,MUL1,ARHGAP5,SNX14,MZT2B,DDRGK1,LRRC40,WDR37,RETSAT,FAR2 |
| 1.431e-02 | -4.25 | SELENOS (selenoprotein S) | protein interactions | 55829 | 48 | 21 | 19454 | 5460 |
ST7,CFTR,UFD1,SEC62,FAF2,OTULINL,EDEM1,SELENOK,GTF2IRD1,PPARG,DERL1,SEC61B,SYVN1,TMT1A,RUSF1,CAV1,SRPK2,DERL2,SVIP,RNF5,KRAS |
| 1.431e-02 | -4.25 | KIF18A (kinesin family member 18A) | protein interactions | 81930 | 48 | 21 | 19454 | 5460 |
PPP1CC,HMOX2,PPP1CB,GKAP1,MYC,CDC16,RRP7A,CDC23,ANAPC4,PNMA2,BRCA1,SLC39A10,HAPSTR1,ITM2B,PML,PTGES3,VIRMA,CDC20,CSE1L,PRNP,KRAS |
| 1.432e-02 | -4.25 | NF-kappa B signaling pathway | KEGG pathways | ko04064 | 94 | 43 | 7161 | 2463 |
NFKBIA,UBE2I,CCL19,TIRAP,LTA,ICAM1,CD40LG,MAP3K14,CXCL8,PRKCQ,CCL4L1,SYK,TICAM2,TAB1,CD40,CSNK2B,BCL10,CSNK2A1,GADD45B,TRAF6,MYD88,NFKB1,TNFAIP3,TRAF1,BCL2L1,TRAF2,BIRC2,LTB,IKBKB,CCL21,TLR4,LY96,CD14,IRAK4,BCL2A1,TAB2,IL1B,CXCL12,TNF,LTBR,RIGI,TICAM1,PRKCB |
| 1.432e-02 | -4.25 | NF-kappa B signaling pathway | KEGG pathways | hsa04064 | 94 | 43 | 7161 | 2463 |
TAB1,BCL2A1,TAB2,CD40,CSNK2B,BCL10,IL1B,CXCL12,TNF,CSNK2A1,GADD45B,LTBR,TRAF6,MYD88,RIGI,NFKB1,TICAM1,TNFAIP3,PRKCB,TRAF1,UBE2I,CCL19,NFKBIA,TIRAP,LTA,BCL2L1,BIRC2,ICAM1,TRAF2,LTB,IKBKB,CCL21,CD40LG,MAP3K14,CXCL8,CCL4L1,PRKCQ,TLR4,LY96,SYK,CD14,TICAM2,IRAK4 |
| 1.432e-02 | -4.25 | Transport of Mature mRNA derived from an Intron-Containing Transcript | REACTOME pathways | R-HSA-159236 | 75 | 33 | 10285 | 3229 |
NCBP2,NXT1,DDX39B,NUP62,THOC3,POLDIP3,SLU7,NUP153,CHTOP,THOC2,MAGOHB,UPF3B,NUP35,FYTTD1,SRSF7,SRSF2,DHX38,CASC3,MIR636,CDC40,ALYREF,SRSF1,NUP50,DDX39A,NUP37,EIF4A3,THOC1,NUP107,MAGOH,THOC6,NUP42,SRSF4,ZC3H11A |
| 1.438e-02 | -4.24 | Interferon gamma signaling | REACTOME pathways | R-HSA-877300 | 94 | 40 | 10285 | 3229 |
B2M,IRF7,IRF9,TRIM8,STAT1,SUMO1,IRF8,ICAM1,CAMK2G,SOCS3,TRIM62,JAK2,TRIM21,IFNG,OAS1,TRIM34,TRIM29,IRF6,IRF2,JAK1,FCGR1A,IRF3,PTPN11,IRF4,TRIM46,TRIM22,MT2A,TRIM35,IFNGR1,TRIM3,TRIM45,PTPN1,PIAS1,TRIM5,IRF1,TRIM6,TRIM68,PML,TRIM26,TRIM10 |
| 1.442e-02 | -4.24 | Rheumatoid arthritis | KEGG pathways | ko05323 | 89 | 41 | 7161 | 2463 |
CCL5,JUN,ATP6V0B,ATP6V1D,CCL20,IL15,ATP6V0E1,TLR2,ATP6V1C1,CXCL12,CCL2,TNF,CD86,ATP6V1E2,CD28,IL1A,IL1B,IL6,CTSK,ATP6V1G2,FOS,CSF2,TGFB2,TGFB3,CXCL1,CCL3,ANGPT1,ACP5,IFNG,CD80,TNFSF13,IL23A,CTLA4,TLR4,IL18,CXCL8,ICAM1,LTB,ATP6V1A,ATP6V1G1,VEGFA |
| 1.442e-02 | -4.24 | Rheumatoid arthritis | KEGG pathways | hsa05323 | 89 | 41 | 7161 | 2463 |
ATP6V1G2,FOS,TGFB2,TGFB3,CSF2,CTSK,CD80,TNFSF13,CCL3,CXCL1,ACP5,ANGPT1,IFNG,IL23A,CTLA4,LTB,ICAM1,ATP6V1A,ATP6V1G1,VEGFA,IL18,TLR4,CXCL8,ATP6V1D,CCL5,JUN,ATP6V0B,IL15,CCL20,ATP6V0E1,TLR2,CD28,ATP6V1E2,IL1A,IL1B,IL6,ATP6V1C1,CXCL12,CCL2,TNF,CD86 |
| 1.449e-02 | -4.23 | IL-1 signaling pathway | WikiPathways | WP195 | 57 | 29 | 5310 | 1910 |
SQSTM1,MAP2K6,MAP2K3,MAP2K1,TAB2,HSPB2,CCL2,AKT1,IKBKB,UBE2N,TRAF6,PIK3R1,MYD88,JUN,IL1B,TAB1,NFKBIA,UBE2V1,PIK3R2,PELI1,PTPN11,MAP3K3,TOLLIP,NFKB1,IL1A,MAP3K14,IRAK4,NFKBIB,IL1RAP |
| 1.452e-02 | -4.23 | ASPRV1 (aspartic peptidase retroviral like 1) | protein interactions | 151516 | 26 | 13 | 19454 | 5460 |
DDX39B,CFAP298,PTEN,RAB9B,MCL1,B3GALNT1,ESR2,CUL2,FCF1,HNRNPA1,SOX2,CCR1,GNB1L |
| 1.452e-02 | -4.23 | TEX13A (testis expressed 13A) | protein interactions | 56157 | 26 | 13 | 19454 | 5460 |
TTC23,SETD3,ASPM,CNOT8,RNF40,CNOT6,CNOT2,BTG3,RNF20,CNOT6L,CNOT7,TXN,ATP5PO |
| 1.452e-02 | -4.23 | GTF2A1L (general transcription factor IIA subunit 1 like) | protein interactions | 11036 | 26 | 13 | 19454 | 5460 |
HMG20A,CEBPE,EMX1,GAB1,PAX9,EMX2,GTF2A2,CSNK2A1,MAFG,RBFOX2,CSK,SUB1,ATF4 |
| 1.452e-02 | -4.23 | GDNF (glial cell derived neurotrophic factor) | protein interactions | 2668 | 26 | 13 | 19454 | 5460 |
RIGI,RANBP10,S100A10,MKLN1,MAEA,GID4,ARMC8,YPEL5,SYP,SCAMP5,COPS5,DDX39A,AGTRAP |
| 1.452e-02 | -4.23 | POU2F2 (POU class 2 homeobox 2) | protein interactions | 5452 | 26 | 13 | 19454 | 5460 |
AQP3,FOXS1,GAPDH,AR,MSX2,DDX39A,TXNRD1,FOXC2,HMGA1,MNAT1,PGR,TMEM108,CYRIB |
| 1.452e-02 | -4.23 | MRPL36 (mitochondrial ribosomal protein L36) | protein interactions | 64979 | 26 | 13 | 19454 | 5460 |
FTL,MRPL22,BRCA1,KCTD10,TAFAZZIN,SKIC8,MRPS21,ATP5F1A,MRPL10,MRPS35,MAX,MYC,CIDEB |
| 1.452e-02 | -4.23 | RNF103 (ring finger protein 103) | protein interactions | 7844 | 26 | 13 | 19454 | 5460 |
UBE2H,UBE2D1,IDH2,HADH,RNF148,UBE2E2,UBE2W,UBE2L3,CTSB,UBE2D3,DERL1,COPS2,UBE2N |
| 1.452e-02 | -4.23 | PRMT9 (protein arginine methyltransferase 9) | protein interactions | 90826 | 26 | 13 | 19454 | 5460 |
HCST,COMTD1,GPR17,STX12,RBM7,YWHAB,ZBTB42,SF3B4,RAB5A,ST6GAL1,STAT1,DUSP26,CCAR2 |
| 1.452e-02 | -4.23 | Tubb4b (tubulin, beta 4B class IVB) | protein interactions | 227613 | 26 | 13 | 19454 | 5460 |
CHCHD4,ICAM1,PFDN2,CYC1,PFDN6,PFDN5,MGST3,PFDN1,AIFM1,CCNF,MAIP1,RRAS2,PTEN |
| 1.452e-02 | -4.23 | CLDN1 (claudin 1) | protein interactions | 9076 | 26 | 13 | 19454 | 5460 |
DRG1,TMEM179B,MMP14,RHOB,LAMTOR1,LAMP3,FNDC9,ARF6,KRAS,CLDN1,CLDN3,RAB35,HRAS |
| 1.452e-02 | -4.23 | Dctn1 (dynactin 1) | protein interactions | 13191 | 26 | 13 | 19454 | 5460 |
DCTN6,PTDSS1,CCNF,C9orf72,DCTN3,DERL1,ACTR1B,ACTR1A,CAPZA2,CDK1,DCTN4,CAPZA1,UQCRQ |
| 1.452e-02 | -4.23 | TSSK2 (testis specific serine kinase 2) | protein interactions | 23617 | 26 | 13 | 19454 | 5460 |
FAM229B,TF,TTR,HSP90AB1,TFG,PTGES3,CACYBP,PPP5C,ZC3H15,SIPA1L1,FKBP4,SERPINA1,HSP90AA1 |
| 1.452e-02 | -4.23 | Erh (ERH mRNA splicing and mitosis factor) | protein interactions | 13877 | 26 | 13 | 19454 | 5460 |
DDX39A,CHTOP,SAMM50,ALYREF,PPP1R12A,DDX39B,CHCHD6,THRAP3,TMOD3,ERH,POLDIP3,FLOT1,CHCHD3 |
| 1.452e-02 | -4.23 | ADAM11 (ADAM metallopeptidase domain 11) | protein interactions | 4185 | 26 | 13 | 19454 | 5460 |
RAB32,MTG2,HPCAL1,CBLN4,RHOBTB3,JAK1,RAB3B,GPIHBP1,MSMB,CLEC12B,TAFAZZIN,EPHA4,APEX1 |
| 1.454e-02 | -4.23 | positive regulation of CD4-positive, alpha-beta T cell activation | biological process | GO:2000516 | 46 | 21 | 18204 | 5365 |
TGFBR2,CD28,CD80,CCL19,IL23A,CD81,IL2RG,KLHL25,MIR21,CD86,SOCS5,CD83,IL18,SASH3,EP300,IFNG,IL12B,XCL1,NLRP3,FOXP3,PRKCQ |
| 1.454e-02 | -4.23 | nuclear membrane organization | biological process | GO:0071763 | 46 | 21 | 18204 | 5365 |
VPS4A,BANF1,UBXN2B,CHMP1A,REEP4,VRK1,UBE2I,VPS4B,AKAP8L,CHMP4C,CHMP2B,PRKCB,TOR1B,CHMP1B,NSFL1C,CDK1,CHMP5,PAFAH1B1,CHMP2A,REEP3,PRKCA |
| 1.454e-02 | -4.23 | protein insertion into membrane | biological process | GO:0051205 | 46 | 21 | 18204 | 5365 |
EMC2,SGTA,EMC4,CAMLG,EMC1,EMC10,TMEM147,RTP4,BAX,EMC9,EMC8,TRAM1L1,MAIP1,TRAM2,BCS1L,EMC6,UBL4A,WDR83OS,SEC61A1,CCDC47,TRAM1 |
| 1.454e-02 | -4.23 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:2001239 | 46 | 21 | 18204 | 5365 |
FGF10,CSF2,SNAI2,TERT,IL7,IFI6,EYA3,MIR198,STRADB,BCL2L1,FGFR1,HTRA2,PRDX2,TNF,AKT1,CTNNA1,IL1A,CX3CL1,PPP2R1A,MCL1,IL1B |
| 1.457e-02 | -4.23 | G-protein_beta_WD-40_rep | interpro domains | IPR020472 | 83 | 34 | 18521 | 5414 |
GNB4,WDR83,BUB3,GNB1,SNRNP40,NLE1,WDR3,TAF5L,SKIC8,ATG16L1,WDR44,PRPF19,PWP2,WDR82,RBBP7,WDR12,WSB1,PRPF4,WDR37,WDR5B,SMU1,PAFAH1B1,FBXW11,PAAF1,POC1B,WDSUB1,TRAF7,DCAF11,PAK1IP1,THOC3,RBBP4,GNB3,WDR38,FBXW7 |
| 1.461e-02 | -4.23 | regulation of CD4-positive, alpha-beta T cell differentiation | biological process | GO:0043370 | 57 | 25 | 18204 | 5365 |
IL2RG,CD86,CBFB,CD80,IL23A,IL12B,RC3H2,IFNG,EP300,KLHL25,BATF,MIR21,CCL19,IRF4,IL2,BCL6,NLRP3,FOXP3,RUNX1,IL18,CD83,SOCS5,JUNB,SASH3,HMGB1 |
| 1.464e-02 | -4.22 | amino acid transport | biological process | GO:0006865 | 132 | 51 | 18204 | 5365 |
SLC1A2,SLC6A2,SLC1A1,SLC7A1,SLC6A12,SLC7A9,SERINC3,KCNJ10,SLC6A3,UCP2,SLC7A11,SLC43A2,SLC7A14,SLC1A3,LRRC8A,SLC6A11,SFXN2,LRRC8B,GRM1,SLC6A7,SH3BP4,SLC6A1,SLC7A8,LRRC8D,SLC38A2,CACNB4,SLC16A10,KCNJ8,SLC32A1,SLC38A1,SLC17A5,SLC25A26,SFXN1,SLC6A4,SLC38A9,CLN8,NHERF1,ARL6IP5,PSEN1,SLC7A4,NTRK2,SLC6A8,VPS54,LRRC8C,GRM2,SLC38A3,SLC25A12,TSPO2,GJA1,SLC38A7,SLC6A6 |
| 1.464e-02 | -4.22 | SLC39A9 (solute carrier family 39 member 9) | protein interactions | 55334 | 132 | 49 | 19454 | 5460 |
MANBAL,IDH2,VAPB,TTI2,ZNF574,NEK7,SLC7A1,PXMP2,HELLS,EP300,FCER1G,VMP1,MFSD14B,B4GALT3,MGST3,ERH,VPS72,B4GALT1,STIM1,EZH2,SLC25A24,CYB5B,SYNGR3,TRAPPC13,CENPM,NEU1,B3GNT2,HPCAL1,APH1A,FKRP,SLC39A3,TM4SF18,TRAPPC2L,CDC23,MOV10,GTF2E1,SNRPD3,DYNC1I2,ANKRD46,RAB1B,TMEM237,CRB3,RMND1,SLC25A17,RAB39B,SSMEM1,SRPRA,MFSD5,EED |
| 1.464e-02 | -4.22 | PHLDB2 (pleckstrin homology like domain family B member 2) | protein interactions | 90102 | 132 | 49 | 19454 | 5460 |
FTL,HSPA8,CLK1,TWNK,FAM53C,DVL2,RTKN,AGAP1,SIPA1L1,DET1,CFTR,INPP5E,ATG16L1,VIRMA,ATP6AP2,DYNLL1,RHOJ,TEX19,RHOB,DCAF4,MYO6,YWHAZ,MAP3K21,RACGAP1,MYC,SFN,FAM110B,SRSF12,FLOT1,G3BP1,KRAS,TRIM37,TESK2,NUPR1,VPS33A,CAPZA2,E2F4,KCTD3,GJA1,RAC2,HRAS,EIF4E2,YWHAB,CAMSAP2,TIAM1,YWHAH,YWHAG,CTNNB1,NDC80 |
| 1.468e-02 | -4.22 | multi-organism reproductive process | biological process | GO:0044703 | 192 | 71 | 18204 | 5365 |
AKT1,CLDN4,ERRFI1,SPP1,IL1B,TGFB3,RGS2,JUNB,PRL,OVGP1,UPRT,ITGA2,LEP,MAGED2,STOX2,OR2H2,POLR1B,IDO1,TCF23,PTGFR,PARP2,STC1,SLC2A1,TAC1,ACSL4,MMP9,RPL29,PNOC,PLA2G4B,PRDX3,OXTR,GJB2,CRHBP,VDR,EPYC,VMP1,TACR1,NDP,TPPP3,PGR,SLC38A3,FKBP4,RLN2,CD38,THBD,EMP2,KLF1,GHRL,DDR1,SOD1,MIR21,AR,CYP1A1,PTN,CNR1,UMPS,PTHLH,CAPN2,CYP27B1,CTSB,SLC6A4,FOS,EPO,DEDD,LDOC1,CRHR1,BMPR2,SLC38A1,KPNA6,UCN,SLC38A2 |
| 1.476e-02 | -4.22 | DVL2 (dishevelled segment polarity protein 2) | protein interactions | 1856 | 531 | 172 | 19454 | 5460 |
SEC62,RFXANK,ISCU,LMO3,RPL27A,DAAM1,EHHADH,THAP2,CSNK1A1,KCTD12,MAP2K1,HSPA8,TIFA,EP300,LCA5,RFC4,RANBP10,DDI1,RNF41,EIF1B,ARHGEF39,PHB2,MAP3K21,PRPF31,BAG3,MCM3,ZNF250,CUL3,H1-1,CCT2,ARHGAP19,CYP3A43,AP2M1,FZD4,CDC7,FAM83B,PHF21A,LMBR1L,SCNM1,APEX2,RSRC1,USP5,PRDX2,CAVIN2,TRIM29,BMP1,TAB1,GABARAPL1,TRAF2,PPP2R1A,KIF2A,EEF2,TOP3B,RAF1,CSNK1E,ZNF263,DLG3,OTULIN,KLHL12,AP2S1,NFKBIL1,MKLN1,FAM168A,HSPD1,MAEA,PSMD12,AP1M1,POLDIP3,ENKD1,RFC2,PSMA1,YWHAG,XPO1,CTNNB1,UBXN6,PRDX1,PRPF19,WWP2,MED4,RPL23,ARMC8,YWHAB,MAP1LC3A,STX5,SLMAP,EGLN3,CEP19,DPPA2,TCP1,CCAR2,CNP,ATG16L1,UBA52,FAM161A,PRKCA,LEMD3,ACACA,CDK1,CSNK1A1L,RPA2,WWP1,PRKCB,DLAT,SQSTM1,TNFAIP1,RPA3,DVL2,GID8,GABARAP,BCL6,HSPA5,KDM1A,SMC4,ATP5F1A,CFL1,EXOC5,TUFM,PCBD1,CARS1,ZNF687,CCNB1,AP2A1,STK11,BAHD1,PIP4K2C,CSNK2B,INHA,PTEN,WDSUB1,HYCC1,ROMO1,SH3BP4,EAF2,MAGOHB,BUB3,ZBTB17,RPGRIP1L,YES1,ZNF581,NECAP2,METTL15,THAP1,PLA2G12A,ATP5PB,TNRC6C,TP53,GRAP2,SPRY1,NECAP1,STX18,PC,SNIP1,CTNND1,FKBP8,PRDX4,ZNF287,CAPZA1,HNRNPK,WASL,CSNK2A1,TPM3,SSX2IP,NOL12,OLFM2,DLGAP4,EFCAB7,AIFM1,EEF1AKMT3,NAA11,SLC25A12,DCUN1D1,HTRA1 |
| 1.479e-02 | -4.21 | GLA | smart domains | SM00069 | 14 | 8 | 9717 | 2575 |
BGLAP,PRRG1,PROS1,F10,F7,F9,F2,MGP |
| 1.479e-02 | -4.21 | Supt5 (suppressor of Ty 5, DSIF elongation factor subunit) | protein interactions | 20924 | 11 | 7 | 19454 | 5460 |
PPIA,MED31,IK,SAP30BP,RPL8,PNO1,PHYHIP |
| 1.479e-02 | -4.21 | SPMAP2 (sperm microtubule associated protein 2) | protein interactions | 51298 | 11 | 7 | 19454 | 5460 |
TTL,RPGRIP1L,MTA2,MDFI,CCT5,MID1IP1,FHL3 |
| 1.479e-02 | -4.21 | DDT (D-dopachrome tautomerase) | protein interactions | 1652 | 11 | 7 | 19454 | 5460 |
FKBP1A,NUP35,RPA2,HNRNPL,PMAIP1,DSTYK,RPA3 |
| 1.479e-02 | -4.21 | RBP7 (retinol binding protein 7) | protein interactions | 116362 | 11 | 7 | 19454 | 5460 |
DDX39A,SOCS4,LHFPL4,HSH2D,PIK3R3,DOK4,NCKIPSD |
| 1.479e-02 | -4.21 | KCNK3 (potassium two pore domain channel subfamily K member 3) | protein interactions | 3777 | 11 | 7 | 19454 | 5460 |
UBA52,SFN,YWHAH,YWHAG,S100A10,YWHAZ,YWHAB |
| 1.479e-02 | -4.21 | NPPC (natriuretic peptide C) | protein interactions | 4880 | 11 | 7 | 19454 | 5460 |
NPR2,EYA3,FZR1,MTMR12,CSK,MME,PTPN1 |
| 1.479e-02 | -4.21 | HSP82 (Hsp90 family chaperone HSP82) | protein interactions | 855836 | 11 | 7 | 19454 | 5460 |
TP53,CDK4,RAF1,CSNK2A1,NFE2L2,SRC,AHSA1 |
| 1.479e-02 | -4.21 | NLRP12 (NLR family pyrin domain containing 12) | protein interactions | 91662 | 11 | 7 | 19454 | 5460 |
RIGI,H2BC9,HSPA8,HSP90AA1,PYCARD,FAF1,KRAS |
| 1.479e-02 | -4.21 | Bud13 (BUD13 homolog) | protein interactions | 215051 | 11 | 7 | 19454 | 5460 |
DHX16,DDX39B,SRSF1,RBMX2,DDX39A,KIN,JADE1 |
| 1.479e-02 | -4.21 | NFKBIZ (NFKB inhibitor zeta) | protein interactions | 64332 | 11 | 7 | 19454 | 5460 |
ERP29,RIGI,DDX39A,EIF4E,RBM3,NFKB1,EZH2 |
| 1.479e-02 | -4.21 | PCNX2 (pecanex 2) | protein interactions | 80003 | 11 | 7 | 19454 | 5460 |
HNRNPL,TOP3B,ORMDL1,PTTG1,VIRMA,ABHD5,UBE2H |
| 1.479e-02 | -4.21 | ZNF567 (zinc finger protein 567) | protein interactions | 163081 | 11 | 7 | 19454 | 5460 |
SPPL3,CBX3,VIRMA,CUL3,HSPD1,PCBD1,DDX39A |
| 1.479e-02 | -4.21 | GLRX2 (glutaredoxin 2) | protein interactions | 51022 | 11 | 7 | 19454 | 5460 |
SFXN1,TXNRD1,PITPNB,FBXO7,GPX4,BAG3,ELF5 |
| 1.479e-02 | -4.21 | FIGN (fidgetin, microtubule severing factor) | protein interactions | 55137 | 11 | 7 | 19454 | 5460 |
SNRNP40,PAX9,HGS,LANCL1,VIRMA,COPS5,DDX39A |
| 1.479e-02 | -4.21 | LAX1 (lymphocyte transmembrane adaptor 1) | protein interactions | 54900 | 11 | 7 | 19454 | 5460 |
IDH1,CREB1,SYK,MGME1,STAMBPL1,GRAP2,NDN |
| 1.483e-02 | -4.21 | regulation of lipid localization | biological process | GO:1905952 | 183 | 68 | 18204 | 5365 |
APOC2,PCSK9,FURIN,SAR1B,PRELID1,NR1H2,LRAT,APOC4,CAV1,C1QTNF1,ATP8A1,MAP2K6,CRHR1,MIR10B,OSBPL8,NUS1,MIR33B,CD36,CRY1,NFKB1,MIR206,MIR301B,MIR148A,MIR17,GHRL,TSPO,LAMTOR1,MIR146A,LPCAT3,PPARG,FIS1,TMEM97,TMEM30A,MIR144,IL1A,MIR185,FITM2,ADIPOQ,TNF,NFKBIA,EHD1,MIR9-1,RETN,PTGES,MIR34A,MIR145,IL6,SURF4,AVPR1B,IL1B,SPP1,REN,AKT1,ZDHHC8,MIF,VSTM2A,SYK,AKT2,HILPDA,ITGAV,FASLG,LEP,PPARA,PTPN11,FITM1,ABHD5,MIR130B,NKX3-1 |
| 1.485e-02 | -4.21 | osteoblast differentiation | biological process | GO:0001649 | 141 | 54 | 18204 | 5365 |
HNRNPC,BCAP29,TP53INP2,MEF2C,CBFB,ASF1A,SEMA7A,FOSL2,BMPR2,WNT10B,ALPL,BMPR1A,ACHE,BMPR1B,MAP2K6,SMAD1,HSPE1,MSX2,IGFBP3,PTHLH,UFL1,HIRA,SNAI2,SYNCRIP,TMT1A,GJA1,ALYREF,CCDC47,PHB1,LGR4,BGLAP,ATP5F1B,ID4,SFRP1,CTNNB1,RRAS2,SIRT7,SMAD3,MIR346,RPS15,AMELX,SMAD4,HAND2,NOG,SMAD5,SPP1,AKT1,DHX9,EPHA2,NR1I3,SOX2,CCL3,JUNB,GABBR1 |
| 1.485e-02 | -4.21 | negative regulation of protein-containing complex assembly | biological process | GO:0031333 | 141 | 54 | 18204 | 5365 |
CAPG,CAPZA2,TRIM11,CPTP,STXBP1,TMOD2,MKKS,SSH3,TMSB4X,TFIP11,STMN2,PTGER4,CSNK1A1,CYRIB,CTNNBIP1,LMO4,HSPA5,MIR17,MIR214,TMOD1,RPL13A,FKBP4,SOX9,MAPRE1,TMOD3,SOST,TMSB10,ADD1,BIRC2,CRYAB,PYDC2,CDC42,VDAC2,EP300,ADD2,SPTBN1,SVIP,RAF1,CAPZA1,LCMT1,SPTAN1,HDAC6,CLIP3,CRBN,EPS8,ABHD17A,HMGB1,CLU,HSPA8,ARFGEF1,DYRK1A,NOP53,SRC,DKK1 |
| 1.485e-02 | -4.21 | positive regulation of blood circulation | biological process | GO:1903524 | 38 | 18 | 18204 | 5365 |
ADRA1A,SCN3B,TGFB2,RGS2,APLN,GHRL,ADM2,TACR3,ATP1A2,UCN,SLC1A1,ADRB1,HSP90AA1,CHGA,MIR1-1,GSK3A,HEY2,ATP1A1 |
| 1.485e-02 | -4.21 | RNGTT (RNA guanylyltransferase and 5'-phosphatase) | protein interactions | 8732 | 129 | 48 | 19454 | 5460 |
BRCA1,LACRT,MED10,UBE2H,RIT1,CDC73,MYC,RNF40,MED17,SNRNP40,ESR2,POLR2B,CMTR1,RAN,CCNF,RPL37A,RPA2,MED23,HNRNPH3,ZNF574,GTF2H4,SUPT4H1,BRIX1,RPA3,NUP50,APPBP2,KPNA1,DDRGK1,CSNK2A1,POLR2I,SNX18,FZR1,ARL10,POLR2L,EEF1AKMT3,RPRD1A,TAF2,POLR2C,POLR2G,PPP4C,POLR2D,SUPT5H,SOX2,RPAP2,KPNA2,KRAS,MRPL22,TCOF1 |
| 1.487e-02 | -4.21 | SLC26A2 (solute carrier family 26 member 2) | protein interactions | 1836 | 51 | 22 | 19454 | 5460 |
SLC20A1,LGALS8,RHOB,RAB5C,TSPAN10,RAB2A,CSK,TNFAIP3,LGALS3,ARF6,LDLR,TMEM74,HRAS,RAB35,CTXN1,VAPB,CTLA4,TMEM59,CLEC12B,KRAS,SLC22A6,MGAT4B |
| 1.487e-02 | -4.21 | PAIP2B (poly(A) binding protein interacting protein 2B) | protein interactions | 400961 | 51 | 22 | 19454 | 5460 |
PRR3,PABPC1L,ALYREF,SRSF1,DKC1,PAIP1,HNRNPA1,MOV10,ELAVL2,PAIP2,CASC3,CIRBP,ZC3H11A,SNIP1,RBM3,PABPC1,H2AX,RBMS2,PABPC5,MRPL11,ZNF326,LARP4B |
| 1.487e-02 | -4.21 | IL4R (interleukin 4 receptor) | protein interactions | 3566 | 51 | 22 | 19454 | 5460 |
DDX39A,SOCS5,UTP6,RHOBTB3,TOP3B,IL2RG,DCAKD,PTPN11,GRB10,DHRS3,STAT6,HGS,IL4,SHC1,JAK1,STX5,CD40,BMPR1A,JAK2,IL13,ARL5B,RHOJ |
| 1.487e-02 | -4.21 | PODXL2 (podocalyxin like 2) | protein interactions | 50512 | 51 | 22 | 19454 | 5460 |
TPBG,FAM234A,PDCD1LG2,CTLA4,NHERF1,LRRN4CL,STX7,GALNT2,TNFSF8,KRAS,CD1B,LAMP2,MOV10,RAB11A,RHOG,CD63,CLRN2,SELL,VIRMA,SPPL3,ARF6,TNFSF18 |
| 1.487e-02 | -4.21 | ADCY6 (adenylate cyclase 6) | protein interactions | 112 | 51 | 22 | 19454 | 5460 |
CHRNB2,YIPF3,CLEC2B,RAF1,CHRNA7,TNFSF12,RIGI,SLC31A1,KRAS,LPAR1,TSPAN15,LGALS8,RHOB,ANKMY2,B4GAT1,CAV1,CX3CL1,SYNE4,LGALS3,MANSC1,TMEM74,HRAS |
| 1.487e-02 | -4.21 | NDUFA11 (NADH:ubiquinone oxidoreductase subunit A11) | protein interactions | 126328 | 51 | 22 | 19454 | 5460 |
NDUFB5,DUSP21,UFL1,NDUFS2,HSCB,NDUFAB1,TP53,NDUFA2,NDUFA12,NDUFA5,GHITM,NDUFS6,NDUFS3,CCNF,NDUFB4,EGLN3,NDUFS8,SLC25A12,NDUFV2,NDUFB6,NDUFB8,UBE2H |
| 1.487e-02 | -4.21 | FRG1 (FSHD region gene 1) | protein interactions | 2483 | 51 | 22 | 19454 | 5460 |
RPA2,EZH2,SNRNP70,SART3,RNF8,UBE2H,RAF1,MYC,JUN,DDRGK1,EXOSC8,CAND1,H3C1,FZR1,COIL,MEPCE,ESR2,GNMT,RPA3,RPL31,ZNF330,EP300 |
| 1.488e-02 | -4.21 | 1-phosphatidylinositol-3-kinase regulator activity | molecular function | GO:0046935 | 15 | 9 | 18094 | 5411 |
CISH,SOCS5,PIK3R3,SLA2,SOCS3,PIK3R2,SOCS4,PIK3R1,SOCS2 |
| 1.488e-02 | -4.21 | human chr6q21 | chromosome location | human chr6q21 | 63 | 22 | 26134 | 5823 |
SNX3,FAM229B,CEP57L1,QRSL1,RPF2,CDC40,MIR587,SMPD2,SEC63,SLC16A10,METTL24,CD164,SOBP,PREP,OSTM1,PDSS2,BVES,POPDC3,MTRES1,FIG4,NR2E1,TRAF3IP2 |
| 1.489e-02 | -4.21 | mitochondrial electron transport, cytochrome c to oxygen | biological process | GO:0006123 | 20 | 11 | 18204 | 5365 |
COX4I1,NDUFA4,COX8A,COX7A1,COX6B1,COX6C,COX7B,COX7B2,COX5A,COX4I2,COX6A2 |
| 1.489e-02 | -4.21 | response to superoxide | biological process | GO:0000303 | 20 | 11 | 18204 | 5365 |
MT3,SOD1,SOD2,GLRX2,SOD3,PRDX1,CYGB,NQO1,UCP2,CCS,PRDX2 |
| 1.489e-02 | -4.21 | positive regulation of monocyte chemotaxis | biological process | GO:0090026 | 20 | 11 | 18204 | 5365 |
CCL1,DEFB124,CXCL12,CREB3,CCR2,CX3CR1,CCL5,AIF1,CCR1,HMGB1,CXCL10 |
| 1.489e-02 | -4.21 | cellular response to estrogen stimulus | biological process | GO:0071391 | 20 | 11 | 18204 | 5365 |
SFRP1,SP1,ESR2,CRHBP,MIR493,TRIM24,AR,MDM2,PELP1,WBP2,SERPINB9 |
| 1.489e-02 | -4.21 | myeloid dendritic cell differentiation | biological process | GO:0043011 | 20 | 11 | 18204 | 5365 |
PSEN1,BATF,CSF2,LTBR,ITGB8,IRF4,TGFBR2,TRAF6,IL4,RBPJ,NOTCH2 |
| 1.490e-02 | -4.21 | MYO18A (myosin XVIIIA) | protein interactions | 399687 | 275 | 94 | 19454 | 5460 |
CYBRD1,PALM2AKAP2,PPP1R12A,STRADB,CAPZA1,TOLLIP,RPL15,TP53,NUPR1,TFRC,ACTR2,ARPC3,CAPZA2,DSTN,RAC2,TES,CDK9,MYL12A,TMPO,SURF6,PPP1R18,HDAC6,TPM3,DPP4,MOV10,DNAJB2,SMAD4,TNFAIP1,RHOU,BAP1,DDX46,FBXW7,CDC42,CFTR,RPS14,SPTBN1,MYL12B,TMOD1,RPA2,PICALM,PTEN,ENO1,CTTN,TECR,VIRMA,CTSB,TMOD3,DAPK3,ARHGAP21,CFL2,CFL1,SFTPA1,DNAJC5,USP14,AR,RAB2A,PYCR2,AP2A1,MYO1B,UTP25,TOMM6,IFNG,KRAS,TRIM37,ISG15,ACTN4,RND3,CHMP4C,CORO1C,PLAC9,SPTAN1,KCTD10,RHOH,FIG4,DDRGK1,HSPA8,TMEM185A,FOS,SPECC1L,STAU1,PPP1CB,MYL6,CSNK1A1,AP2M1,GTF2F1,DLST,EFHD2,ESR2,ACTB,BTF3,MYC,CUL3,RHOB,MYO6 |
| 1.490e-02 | -4.21 | sperm midpiece | cellular component | GO:0097225 | 55 | 24 | 19108 | 5553 |
HSP90AA1,CCR6,ADGB,SQSTM1,VDAC2,TOMM20,GABARAP,CCDC172,IFT172,SPMIP6,AK2,PACRG,CD52,RAP1A,TACR1,GARIN2,GK2,ATG16L1,NHERF1,TACR3,DEFB1,LYZL6,PPP3R2,HSPD1 |
| 1.490e-02 | -4.21 | eukaryotic translation initiation factor 4F complex | cellular component | GO:0016281 | 13 | 8 | 19108 | 5553 |
EIF4H,EIF4A2,EIF4B,EIF4E,EIF4E2,EIF4EBP3,EIF4E3,OTUD6B |
| 1.492e-02 | -4.21 | - | gene3d domains | 1.20.1250.10 | 53 | 23 | 14470 | 4137 |
IFNA13,EPO,OSM,IL2,IFNK,IL10,CSH1,IL13,IL6,IL3,CSF2,IL23A,PRL,IL12A,IFNG,LEP,IFNA10,IFNA2,IL5,IFNB1,GH1,IL4,IL22 |
| 1.493e-02 | -4.20 | KBTBD7 (kelch repeat and BTB domain containing 7) | protein interactions | 84078 | 214 | 75 | 19454 | 5460 |
MTRES1,EIF4B,UBE2M,ZNF574,IDH2,MRPS34,APOBEC3C,GABARAPL2,FGF13,PIP5K1A,FGF17,GABARAP,RGS2,CDC42EP4,MRPL57,GREM2,CCDC106,SNX33,APPBP2,MRPL34,SIRT7,FOS,NOG,TMEM160,UBE2H,HSP90AA1,MRPS25,TXNIP,CUL3,MRM2,LMO2,KBTBD6,RPL10,VIRMA,LRIF1,SFRP4,MTM1,AP2M1,MRPS28,SURF2,POP7,DOK4,H2BC1,NFKBIL1,TULP3,KIF2A,METTL15,EMILIN3,GABARAPL1,MAP1LC3B,JPH4,CCT5,MARCKSL1,MRPS17,FGF12,NEDD8,ZC3H11A,HAPSTR1,KLHL24,TFPT,FAF1,CAMSAP2,MRPS26,TIAM1,MRPL18,FOSL2,INO80E,PLEKHO1,ZNF24,PDIA3,WDR44,CCAR2,MRPS9,THOC2,TNIK |
| 1.493e-02 | -4.20 | AP1B1 (adaptor related protein complex 1 subunit beta 1) | protein interactions | 162 | 214 | 75 | 19454 | 5460 |
CFTR,SYNRG,ARHGAP1,CLDN4,PRKAB1,HEXIM1,RPA2,EP300,MEA1,HSPA8,SIRT7,RPA3,BAP1,DVL2,GTF2I,CUL3,RAB11A,CREBBP,AP2A1,SMAD2,LAMTOR1,AP1G2,AP2M1,SMAP2,ARF1,LMBR1L,VIRMA,APEX1,MAT2B,VKORC1L1,MYG1,RNF39,NECAP2,TP53,RANBP1,RAF1,ARFGAP1,SGIP1,AP2S1,AP1S2,GPBP1L1,RAB4A,PSORS1C2,NECAP1,SIGLECL1,NTRK2,COX8A,SLC2A8,ABCE1,HAPSTR1,HNRNPA2B1,AP1M1,LAMP3,XPO1,COPS5,SNAP91,INSYN1,ZCCHC10,KARS1,IFI16,FNDC11,LAMP2,ATG9A,STAMBPL1,AGR2,SHC1,COMT,CDC5L,G6PD,TRMT61A,STX6,FCHO2,AFTPH,PLEKHF2,ARF6 |
| 1.494e-02 | -4.20 | positive regulation of positive chemotaxis | biological process | GO:0050927 | 25 | 13 | 18204 | 5365 |
SMAD3,SCG2,CXCL12,CCR4,F7,CXCL8,AGER,ITGA2,VEGFC,FGF10,NTRK3,VEGFA,CDH13 |
| 1.494e-02 | -4.20 | mitochondrial cytochrome c oxidase assembly | biological process | GO:0033617 | 25 | 13 | 18204 | 5365 |
UQCC6,COX14,COA1,TIMM21,PET117,COX16,TACO1,COA5,BCS1L,COX20,COA4,COX17,COX19 |
| 1.494e-02 | -4.20 | synaptic vesicle maturation | biological process | GO:0016188 | 25 | 13 | 18204 | 5365 |
PICALM,RAB3A,DLG4,SNAPIN,ATP6V1D,ATP6V1G1,ATP6AP2,ATP6V1G2,ZDHHC15,ATP6V1C1,ATP6V1A,STXBP1,SYP |
| 1.494e-02 | -4.20 | cellular response to copper ion | biological process | GO:0071280 | 25 | 13 | 18204 | 5365 |
AQP2,MT1A,NFE2L2,MT3,CYP1A1,MT1E,BECN1,MT1M,MT1X,MT2A,PRNP,MAP1LC3A,BACE1 |
| 1.494e-02 | -4.20 | positive regulation of endothelial cell apoptotic process | biological process | GO:2000353 | 25 | 13 | 18204 | 5365 |
PDCD4,MIR375,CD248,CD40LG,MIR15A,FASLG,CCL2,MIR101-1,MIR132,MIR24-1,MIR125A,RGCC,CD40 |
| 1.496e-02 | -4.20 | Development and heterogeneity of the ILC family | WikiPathways | WP3893 | 32 | 18 | 5310 | 1910 |
IL12A,IL18,GFI1,IL13,IL22,ZBTB16,TNF,IL23A,IL1B,IFNG,IL4,IL7,IL12B,IL6,IL5,TOX,IL15,NFIL3 |
| 1.497e-02 | -4.20 | female pregnancy | biological process | GO:0007565 | 171 | 64 | 18204 | 5365 |
PRL,JUNB,OVGP1,CLDN4,AKT1,RGS2,TGFB3,IL1B,SPP1,ERRFI1,POLR1B,STOX2,UPRT,MAGED2,LEP,ITGA2,STC1,ACSL4,SLC2A1,TCF23,IDO1,PARP2,CRHBP,GJB2,EPYC,VMP1,VDR,PNOC,RPL29,MMP9,PRDX3,OXTR,THBD,CD38,DDR1,GHRL,EMP2,KLF1,RLN2,FKBP4,SLC38A3,NDP,PGR,TPPP3,PTHLH,CAPN2,PTN,AR,MIR21,SOD1,UMPS,CNR1,FOS,EPO,CYP27B1,CTSB,UCN,KPNA6,SLC38A1,BMPR2,SLC38A2,CRHR1,LDOC1,DEDD |
| 1.498e-02 | -4.20 | - | gene3d domains | 3.30.70.330 | 245 | 86 | 14470 | 4137 |
RDM1,PABPC1,HNRNPD,RBM27,CPEB1,RBM7,HNRNPF,SART3,TIA1,PABPC5,RBM5,RBFOX3,TNRC6C,SNRPA,SRSF8,LEMD3,RBFOX2,HNRNPAB,IFI35,SF3B4,RBM42,PSPC1,SRSF1,POLDIP3,RRP7A,RBM12,SF3B6,RBMX2,HNRNPA0,HNRNPA2B1,NONO,G3BP1,HNRNPH3,MATR3,TRA2B,RBM3,GRSF1,LARP4B,SRSF2,SRSF10,NMI,RBM41,EIF3G,RPL23A,UHMK1,HNRNPA1,HNRNPC,ELAVL2,PPIL4,NCBP2,SNRPB2,SYNCRIP,MRPL23,G3BP2,RBM15B,SRSF4,CSTF2T,NUP35,SNRNP70,SRSF7,EIF4B,CELF6,RBM23,RBM38,BOLL,UPF3B,TRA2A,HNRNPDL,SRSF12,RALYL,RBM18,ELAVL4,IGF2BP1,ALYREF,RBM34,MYEF2,R3HCC1,ZCRB1,EIF4H,RBM17,EWSR1,RBMS2,RBM22,HNRNPL,HNRNPH2,CIRBP |
| 1.499e-02 | -4.20 | Regulation of TP53 Activity through Acetylation | REACTOME pathways | R-HSA-6804758 | 31 | 16 | 10285 | 3229 |
TP53,PIP4K2C,AKT2,RBBP4,AKT3,AKT1,MBD3,PIP4P1,RBBP7,MAP2K6,ING2,MTA2,ING5,MEAF6,EP300,PML |
| 1.499e-02 | -4.20 | Uptake and actions of bacterial toxins | REACTOME pathways | R-HSA-5339562 | 31 | 16 | 10285 | 3229 |
CD9,HSP90AA1,VAMP2,SV2B,TXNRD1,MAP2K1,SYT2,MAP2K3,EEF2,STX1A,VAMP1,HSP90AB1,SNAP25,HBEGF,FURIN,MAP2K6 |
| 1.499e-02 | -4.20 | Processing of Capped Intronless Pre-mRNA | REACTOME pathways | R-HSA-75067 | 31 | 16 | 10285 | 3229 |
SNRPE,CPSF2,CLP1,SNRPB,CPSF1,MIR1234,CSTF2T,CPSF4,ZNF473,SNRPG,LSM10,MIR939,PAPOLA,NCBP2,SNRPD3,CSTF3 |
| 1.499e-02 | -4.20 | maintenance of location | biological process | GO:0051235 | 168 | 63 | 18204 | 5365 |
CCDC22,CD4,PSEN1,LIPA,TOPORS,STARD4,SKP1,BSCL2,SUFU,PGR,TSPO,HSPA5,YWHAB,IGSF11,HEXB,SRI,SUPT7L,FAF1,KDELR1,CD36,CRY1,HSP90B1,PML,TMSB4X,ARL2BP,OS9,RIT2,CIDEB,MDFI,LDAH,PSMD10,CAV1,RER1,FTL,FKRP,CER1,INSIG2,FTHL17,PDIA2,FITM1,S100A8,AKT1,IL1B,CDK5,SRGN,ARHGAP21,ASPM,NPC2,FTH1,KDELR2,HEXA,TXN,TMSB10,TBCCD1,GPAA1,CALR,IL10,PAFAH1B1,NFKBIA,FITM2,ACVR1C,G3BP2,TNF |
| 1.499e-02 | -4.20 | FGFR4 (fibroblast growth factor receptor 4) | protein interactions | 2264 | 455 | 149 | 19454 | 5460 |
GLCE,IGF1R,TGFBR2,RASL10B,ARF4,RNF20,MTA3,SNAP29,TP53,CDK4,MAP2K3,PIK3CA,ARPC3,ELSPBP1,AIP,EHBP1,MAP2K6,SLC39A10,SEC23A,CDK6,CDCA3,KCTD3,FZR1,FCHO2,GRM1,CDK9,RELL1,KLHL22,SHC1,BECN1,DNAJC7,SEPTIN6,YKT6,NF2,GPIHBP1,FTSJ1,USP8,PIK3R2,CHMP2B,ARHGAP1,KDELR2,EDF1,NTPCR,SYNRG,CDK1,FGFR1,HEXIM1,MET,UBE2M,GXYLT1,VAMP3,GAB1,SMAP2,DNASE1L1,MSN,ALB,EPCAM,FERMT2,SRC,AKT1,PTPN11,CEP85,DEPDC1B,GORASP2,SDF2L1,ARFGAP3,EPHA2,STK11,CASC3,MAPRE1,CALU,SCYL2,TMEM87A,NDUFA4,FGF3,CDKN2C,ERP29,FHL3,LASP1,EPHA4,TFG,AHCYL1,ERRFI1,ARFGAP1,RAF1,PI15,TMEM59,CBLN4,ERLIN2,SCHIP1,NUDT19,GTPBP1,NCR3,CRKL,HGS,WDR6,TNIK,PTK7,DNM2,SWAP70,TSG101,NRSN1,DNAJB9,CX3CL1,OCRL,SNX2,MPP1,DIRAS3,ERLIN1,CACYBP,HSP90AB1,WDR44,WIF1,PDIA3,PIK3R1,CFC1,FGF1,PPFIBP1,SPATA2,NCR3LG1,NCK1,CBL,PPP3CA,YWHAB,TERT,HADHA,CYFIP2,UNC45A,USP6NL,MTMR6,NOTCH2,SHMT1,FGF17,PAK2,GTF2IRD1,SLC25A3,FGF7,STAT1,MB21D2,MYC,NIBAN2,PIK3R3,NXPH3,GGH,KIAA1191,MYO6,SCFD1,HSP90AA1,SLC38A1 |
| 1.499e-02 | -4.20 | cellular response to steroid hormone stimulus | biological process | GO:0071383 | 153 | 58 | 18204 | 5365 |
DDIT4,TFPI,NKX3-1,PHB2,PPARA,ADTRP,CST11,RXRG,TRIP4,UGT1A1,ATP5F1A,FAM107A,PTGES3,YWHAH,MGARP,ERRFI1,KLF9,HSPA8,AIFM1,SRC,ATP1A1,PAQR8,IGF1R,EIF4E,FBXO32,UBE2L3,GJB2,PHB1,PADI2,DDX5,TAF7,STC1,UBE3A,RNF14,CALR,VPS54,ATP1A3,ATP1A2,AR,RWDD1,TADA3,PCK2,RAN,NR2E1,PGR,FKBP4,CYP1B1,EGLN2,GSK3A,ESR2,MSTN,JAK2,OR51E2,SMYD3,ABHD2,WBP2,USP8,RBFOX2 |
| 1.501e-02 | -4.20 | negative regulation of gene expression, epigenetic | biological process | GO:0045814 | 159 | 60 | 18204 | 5365 |
SMARCA5,CBX3,PCGF3,PIWIL4,MACROH2A2,BCL6,NRDE2,MORC2,TRIM37,LMNA,HMGB1,DDX4,H2AC13,TRIM27,POLE3,MBD3,ALKBH4,EED,LMNB1,HDAC6,PIWIL2,H2AC6,PRMT5,H2AZ1,SIRT7,MAEL,RLIM,H2AC7,BAHD1,CBX5,MYC,BRCA1,H2AC4,SUV39H1,H2AC1,H2AB1,HELLS,PPM1D,CREBZF,ARB2A,H2AZ2,H2AJ,PHF1,IFI16,RBM15B,MECP2,MACROH2A1,SDR16C5,SIN3A,H2AC25,RB1,ING2,EZH2,SMCHD1,LHX2,EZH1,HDAC5,H2AX,LRIF1,PIWIL1 |
| 1.502e-02 | -4.20 | Plasma membrane estrogen receptor signaling | Pathway Interaction DB | er_nongenomic_pathway | 26 | 15 | 2226 | 782 |
ROCK2,PIK3R1,PLCB1,MSN,SRC,MMP9,PIK3CA,PELP1,GNB1,IGF1R,AKT1,ESR2,PLCB2,HBEGF,GNG2 |
| 1.506e-02 | -4.20 | Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | REACTOME pathways | R-HSA-176407 | 19 | 11 | 10285 | 3229 |
UBE2D1,CDC16,CDC23,ANAPC15,CDC20,ANAPC2,ANAPC16,CDC26,FZR1,ANAPC4,ANAPC11 |
| 1.506e-02 | -4.20 | Protein methylation | REACTOME pathways | R-HSA-8876725 | 19 | 11 | 10285 | 3229 |
METTL21A,EEF2,METTL22,EEF2KMT,KIN,ETFB,ETFBKMT,HSPA8,VCPKMT,RPS2,EEF1A1 |
| 1.506e-02 | -4.20 | Phosphorylation of the APC/C | REACTOME pathways | R-HSA-176412 | 19 | 11 | 10285 | 3229 |
CDC23,ANAPC15,CDK1,ANAPC2,UBE2D1,CDC16,ANAPC11,ANAPC4,CCNB1,ANAPC16,CDC26 |
| 1.506e-02 | -4.20 | Synthesis, secretion, and deacylation of Ghrelin | REACTOME pathways | R-HSA-422085 | 19 | 11 | 10285 | 3229 |
UCN,SEC11A,ACHE,IGF1,SPCS2,GHRL,SPCS1,LEP,KLF4,SPCS3,GH1 |
| 1.506e-02 | -4.20 | Signaling by FGFR2 IIIa TM | REACTOME pathways | R-HSA-8851708 | 19 | 11 | 10285 | 3229 |
GTF2F2,POLR2C,POLR2G,POLR2F,NCBP2,POLR2B,FGF1,POLR2L,POLR2I,POLR2D,GTF2F1 |
| 1.506e-02 | -4.20 | NMNAT1 (nicotinamide nucleotide adenylyltransferase 1) | protein interactions | 64802 | 126 | 47 | 19454 | 5460 |
LYAR,CGAS,CDC5L,SURF6,ZBTB2,RPL8,SRSF1,KPNA1,IFI16,PLEKHO1,WWP2,DDRGK1,KRAS,KPNA2,SNIP1,PPAN,RPL23A,EFNB1,RPL3,PICK1,NTRK2,POLR2D,NUPR1,RAF1,TP53,H1-3,SOX2,RPL35,RPL22,ESR2,FGFBP1,H1-1,RPL7A,ZNF668,GORASP2,KPNA6,DGCR8,NPM3,MSX1,RPL4,STAU1,NOP53,RNASE1,UTP23,APOBEC3C,H1-5,FGF13 |
| 1.506e-02 | -4.20 | KCTD17 (potassium channel tetramerization domain containing 17) | protein interactions | 79734 | 126 | 47 | 19454 | 5460 |
SPECC1L,PCGF2,UFL1,FBXW7,GNB4,MTMR6,PIP5K1A,CDK7,GLRA2,UBE2M,IRF2BPL,ACACA,NUDT18,OPTN,EIF2AK2,CTU1,PPP1R10,GNB1,ZNF687,CUL3,TYW3,SLC1A3,MGAT5B,NIF3L1,STN1,UBE2H,HAPSTR1,PSMA1,PTPN4,KCTD17,RWDD4,FBP1,TP53,TMEM45A,DISC1,SFTPC,EIF1AX,STK16,CERK,KCND2,NLRP1,DBR1,FZR1,CGGBP1,GNG2,DDRGK1,UBE2D1 |
| 1.508e-02 | -4.19 | N-glycan trimming in the ER and Calnexin/Calreticulin cycle | REACTOME pathways | R-HSA-532668 | 36 | 18 | 10285 | 3229 |
EDEM1,OS9,RNF139,DERL1,CALR,PDIA3,PSMC1,DERL2,RNF103,RNF5,UBA52,GANAB,RAD23B,RPS27A,EDEM2,UBB,EDEM3,SYVN1 |
| 1.508e-02 | -4.19 | ovary-carcinoma-mixed_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mixed_carcinoma | 23 | 12 | 16828 | 4835 |
FBXW7,IDH2,PPP2R1A,CTNNB1,TP53,BRCA1,PTEN,DICER1,PIK3CA,IDH1,KRAS,SMAD4 |
| 1.508e-02 | -4.19 | ovary-germ_cell_tumour-teratoma | COSMIC cancer mutations | ovary-germ_cell_tumour-teratoma | 23 | 12 | 16828 | 4835 |
DICER1,PTEN,TP53,KIT,PPP2R1A,IDH2,JAK2,SMAD4,SF3B1,KRAS,HRAS,IDH1 |
| 1.508e-02 | -4.19 | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma | 23 | 12 | 16828 | 4835 |
STK11,SS18,SF3B1,HRAS,KRAS,TERT,KIT,MET,CTNNB1,TP53,ETV6,CDKN2C |
| 1.512e-02 | -4.19 | adrenal_gland-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-pheochromocytoma | 50 | 22 | 16828 | 4835 |
KIT,MET,TP53,NF2,JAK2,FBXW7,FGFR1,TERT,PTEN,KRAS,IDH1,SMAD4,CTNNB1,RB1,AKT1,PTPN11,IDH2,PIK3CA,SMARCB1,HRAS,STK11,MAX |
| 1.512e-02 | -4.19 | energy reserve metabolic process | biological process | GO:0006112 | 74 | 31 | 18204 | 5365 |
MT3,LEPR,PPP1CC,PPP1R1A,GSK3A,GABARAPL1,ATG3,PPP1R3C,GBE1,PYGM,UGP2,STBD1,GFPT1,PHKA1,PPP1CB,PPP1R2,PYGB,LEP,GYS1,WDR45,GNMT,PHKG1,IL6ST,PHKB,PID1,AKT1,RB1CC1,COMT,AKT2,ADRB3,PTGES3 |
| 1.516e-02 | -4.19 | bZIP_sf | interpro domains | IPR046347 | 52 | 23 | 18521 | 5414 |
ATF4,CREB3L4,CEBPG,BATF,ATF3,CEBPE,NFIL3,XBP1,FOSL2,CREB3,ATF1,HLF,JUN,TEF,BACH1,CREB1,MAFG,FOS,CREBZF,JUNB,NFE2,NFE2L2,CREBL2 |
| 1.517e-02 | -4.19 | Formation of TC-NER Pre-Incision Complex | REACTOME pathways | R-HSA-6781823 | 54 | 25 | 10285 | 3229 |
POLR2C,CCNH,GTF2H4,PRPF19,COPS7A,COPS7B,POLR2I,COPS5,ERCC3,POLR2G,POLR2F,TCEA1,COPS2,UBB,RPS27A,GTF2H2,POLR2D,UBA52,POLR2L,COPS4,GTF2H5,CDK7,POLR2B,EP300,MNAT1 |
| 1.522e-02 | -4.19 | endoplasmic reticulum-Golgi intermediate compartment | cellular component | GO:0005793 | 134 | 51 | 19108 | 5553 |
CD59,CTSC,TMED3,TMEM203,SEC22B,STX17,FOLR1,RAB37,TMED1,GALNT1,TMED9,LAMP5,HMGB1,VMP1,TAPBP,BET1,RGMB,RAB6B,RAB1B,COPZ2,YIF1A,MGAT4A,AZIN2,CALR,SERPINH1,TMEM199,PDIA6,KDELR1,YKT6,PROM1,MGAT1,TMED5,MTMR6,SURF4,GOSR2,TMED7,CHP1,RER1,GJB2,CNIH4,CLN8,CNIH1,LMAN1,SERPINA1,HSPA5,MGAT4B,SPPL3,STX5,GRIA1,TMED4,RAB2A |
| 1.526e-02 | -4.18 | EXOSC10 (exosome component 10) | protein interactions | 5394 | 211 | 74 | 19454 | 5460 |
TP53,RAF1,EXOSC8,RPL15,SOX2,DXO,EXOSC3,NKRF,RPL31,RPS24,RUVBL2,NOC4L,KRAS,H3C1,SSRP1,CCAR1,WWP2,MOV10,IFI16,DDRGK1,DIS3L,B9D1,PSMD7,SNRNP70,MPHOSPH10,DRG1,MPHOSPH6,POU5F1,EIF4E2,SUMO2,CAND1,RPS16,CDC5L,MTF1,SYK,RPE,LSM2,GRM2,TOX4,PALS2,RPA2,UPF3B,SIRT7,BAP1,RPA3,C1D,EXOSC4,TXNL1,FBXW7,RPL4,WDR3,UFL1,LSM8,RNF11,CUL3,MYC,CHPF,AR,USP14,PSMD1,BRCA1,RC3H2,RBM7,UBE2H,RIT1,EXOSC1,EIF2AK2,ZNF330,PSPC1,CCNF,USP16,MATR3,VIRMA,SMURF1 |
| 1.526e-02 | -4.18 | BRMS1L (BRMS1 like transcriptional repressor) | protein interactions | 84312 | 123 | 46 | 19454 | 5460 |
RBBP4,PHF12,ELK3,ING2,MYC,HNF1B,SMARCA5,EXOC5,CEP70,BRMS1,KDM1A,TGIF2LX,MBD3,MXD1,KLF3,LACC1,KLF12,SHPRH,KLF9,SIN3A,H2AZ1,MYBL2,EED,GATAD1,H2AC4,CHCHD1,DPY30,CSNK2A1,H3C1,RBBP7,PHF1,PAX6,TGIF2,KLF10,EZH2,HBP1,MTA2,MTA3,MAX,ZNF704,PHF23,SOX2,ING1,TULP3,ELF1,SAP30 |
| 1.526e-02 | -4.18 | USP1 (ubiquitin specific peptidase 1) | protein interactions | 7398 | 123 | 46 | 19454 | 5460 |
KPNA2,CSE1L,VRK1,KIT,ANP32B,UBE2A,RPS4X,PCNA,EZH2,CERK,TP53,SUPT5H,TBK1,MAX,MGARP,SHPRH,RPS16,FZR1,OS9,SYNCRIP,USP46,TRAF6,HSPB1,KPNA1,LYZ,ZCCHC10,VPS26A,UBE2K,UNC45A,NMRAL1,JUP,HNRNPH3,ZNF428,TRIM46,TAGLN2,STAT2,UBB,CCNF,PTEN,CALML5,WDR20,TAFAZZIN,CIRBP,PHF7,AKT1,MYC |
| 1.526e-02 | -4.18 | YIF1A (Yip1 interacting factor homolog A, membrane trafficking protein) | protein interactions | 10897 | 123 | 46 | 19454 | 5460 |
LAMP3,RAB5C,MARCHF5,TMEM248,MSMO1,SNX2,PLEKHF2,HSD17B11,TMEM14B,RPN1,TMEM31,PPIF,YIPF4,NCSTN,CDK2AP2,PTGES,BSCL2,RIC3,FCER1G,SNX10,SCN3B,CNRIP1,KDSR,APEX1,GPR37,CLRN2,MYG1,REEP4,MGST3,COPE,SEC61B,ELOVL4,LMBR1L,SSR1,SDCBP,ZDHHC16,YIPF5,OTULINL,CDC42,SEC62,TIMMDC1,ZDHHC17,CERS2,SLC22A6,SNX11,TMX2 |
| 1.526e-02 | -4.18 | UBASH3A (ubiquitin associated and SH3 domain containing A) | protein interactions | 53347 | 123 | 46 | 19454 | 5460 |
HSP90B1,ZBTB42,DDIT4L,PSMC4,SPMIP6,UBLCP1,RNF41,PSMC1,ARRDC3,TRIM5,FAM83A,HSP90AA1,CXXC5,PFDN2,PDE7A,FGFR1OP2,CSK,TAX1BP1,ACTB,UBB,UBE2L3,VPS72,SLA2,UBASH3B,SF3B4,TRIM27,DISC1,SPRY1,PNMA5,KIAA0408,WBP11,TRIM37,WASL,SNRNP48,STX11,DLG1,HSPD1,SOS2,ABCE1,CBL,NEUROD2,CD247,TRIM8,AIFM1,DNM2,DLGAP4 |
| 1.529e-02 | -4.18 | TIMP1 (TIMP metallopeptidase inhibitor 1) | protein interactions | 7076 | 37 | 17 | 19454 | 5460 |
GGH,DDX39A,TSHR,MMP14,EZH2,SDF2L1,NCR3,KLK5,NTRK3,CD63,CHST10,TMEM87A,EEF1B2,MMP9,CST11,ZBTB16,SLC37A4 |
| 1.529e-02 | -4.18 | CD22 (CD22 molecule) | protein interactions | 933 | 37 | 17 | 19454 | 5460 |
BIRC5,AP2A1,SHC1,PIK3CA,CFTR,NTAQ1,HP,SYK,ATG16L1,PIK3R1,FABP4,LCP2,ANKRD46,MTDH,AP2M1,ST6GAL1,ATP2B4 |
| 1.529e-02 | -4.18 | PADI3 (peptidyl arginine deiminase 3) | protein interactions | 51702 | 37 | 17 | 19454 | 5460 |
NFKB1,PTDSS1,KDELR2,NPSR1,CAPZA2,SGIP1,CSGALNACT1,PML,FOS,MAP1LC3A,RRAS2,OAZ3,RAP1B,LDLR,CPLX3,FBXL4,RAB11B |
| 1.529e-02 | -4.18 | S100A13 (S100 calcium binding protein A13) | protein interactions | 6284 | 37 | 17 | 19454 | 5460 |
STK4,FBXO7,CCL5,FGF1,SNRNP27,CENPM,IRF9,HSPA14,UBE2H,SDC2,IGBP1,PHYHIP,EEF1G,TNF,IL1A,PLEKHF2,MGST3 |
| 1.529e-02 | -4.18 | GPR183 (G protein-coupled receptor 183) | protein interactions | 1880 | 37 | 17 | 19454 | 5460 |
VAMP3,SDC4,AMIGO1,LRRC8A,EIF2B5,GPC1,EIF2B2,SEC63,FAM193B,GPC4,SEC62,SDC2,BZW2,EIF2B3,SMDT1,NRP1,OSBPL8 |
| 1.529e-02 | -4.18 | ROBO2 (roundabout guidance receptor 2) | protein interactions | 6092 | 37 | 17 | 19454 | 5460 |
BNIP3L,CAV1,RDH11,TMEM237,PPP1R1B,SSRP1,TMEM248,KRAS,NR1H2,PRNP,GJA1,OLFM2,CPE,RHOB,KIF2A,MYC,KIF1C |
| 1.529e-02 | -4.18 | TFAP2C (transcription factor AP-2 gamma) | protein interactions | 7022 | 37 | 17 | 19454 | 5460 |
TRIM37,ASF1A,IRAK4,NR1I2,CITED1,UBN1,PNO1,HIRA,EP300,UBE2I,BRCA1,GPR22,IKBKB,EZH2,TP53,MYC,API5 |
| 1.529e-02 | -4.18 | CARD11 (caspase recruitment domain family member 11) | protein interactions | 84433 | 37 | 17 | 19454 | 5460 |
STUB1,PRKCB,RBCK1,TAB1,TRIM37,SRPK2,PRKCQ,CCND1,USP2,DPP4,TNFAIP3,COPS5,PPP2R1A,TRAF6,BCL10,RNF181,CSNK1A1 |
| 1.532e-02 | -4.18 | LPS and Citrate Signaling and Inflammation | SMPDB pathways | SMP0100046 | 22 | 14 | 1369 | 531 |
TIRAP,SDHC,SDHB,SLC25A1,MYD88,IKBKB,ACACA,TRAF6,NFKBIA,TLR4,LY96,NFKB1,MDH1,CD14 |
| 1.533e-02 | -4.18 | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | REACTOME pathways | R-HSA-446193 | 78 | 34 | 10285 | 3229 |
FPGT,DOLK,ST3GAL4,ST6GAL1,ST8SIA4,UAP1,CTSA,GNPNAT1,ST8SIA5,SLC17A5,ST3GAL2,SLC35C1,GMPPB,NUS1,ALG11,GMDS,ALG5,MPDU1,ST6GALNAC3,DPAGT1,NANP,SLC35A1,ST3GAL5,GMPPA,GFPT1,DPM2,CMAS,PMM2,ALG2,NEU1,GFUS,ST3GAL1,MVD,SRD5A3 |
| 1.533e-02 | -4.18 | ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | ex-pleomorphic_adenoma_carcinoma | 18 | 10 | 16828 | 4835 |
FBXW7,CTNNB1,KRAS,HRAS,MET,TP53,PTEN,SMAD4,STK11,PIK3CA |
| 1.533e-02 | -4.18 | salivary_duct_carcinoma | COSMIC cancer mutations | salivary_duct_carcinoma | 18 | 10 | 16828 | 4835 |
PIK3CA,STK11,SMAD4,PTEN,TP53,KRAS,CTNNB1,HRAS,MET,FBXW7 |
| 1.533e-02 | -4.18 | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | 18 | 10 | 16828 | 4835 |
PIK3CA,STK11,SMAD4,PTEN,TP53,CTNNB1,KRAS,MET,HRAS,FBXW7 |
| 1.533e-02 | -4.18 | fibroblastic | COSMIC cancer mutations | fibroblastic | 18 | 10 | 16828 | 4835 |
NF2,CDKN2C,AKT1,KRAS,RB1,HRAS,PTEN,SMAD4,PIK3CA,TERT |
| 1.535e-02 | -4.18 | TBC1D9 (TBC1 domain family member 9) | protein interactions | 23158 | 54 | 23 | 19454 | 5460 |
EFNB1,RAB9A,SRSF2,KRAS,ROCK2,VRK1,GABARAPL1,MAP1LC3B,FAXC,STXBP1,GABARAPL2,TOP3B,SNRPE,PIP4P2,MAP1LC3A,VIRMA,LANCL1,LAMP3,LAMP2,RAB2A,LAMTOR1,MUL1,STK24 |
| 1.535e-02 | -4.18 | SNX19 (sorting nexin 19) | protein interactions | 399979 | 54 | 23 | 19454 | 5460 |
ST7,SEC62,DNAJC25,OTULINL,DDX39A,SSR1,RPN1,STIM1,VAPB,TSPAN15,TMT1A,DERL1,APH1A,TSPAN5,SLC6A8,RAB5C,ESYT1,PTPN1,SEC61B,HSD17B11,DNAJC1,VIRMA,TMPO |
| 1.535e-02 | -4.18 | GNB1L (G protein subunit beta 1 like) | protein interactions | 54584 | 54 | 23 | 19454 | 5460 |
RNF7,PIH1D1,RNF181,EIF1AD,NMRAL1,HSPA8,RABGGTB,KRAS,HSPA5,CUL3,GSTM3,DDRGK1,MTPN,DNAJC10,PLEKHJ1,CCT2,RIT1,UBE2H,CCNF,DNAJB9,CCT7,EGLN3,POLE3 |
| 1.535e-02 | -4.18 | AP1S2 (adaptor related protein complex 1 subunit sigma 2) | protein interactions | 8905 | 54 | 23 | 19454 | 5460 |
STX8,COMT,AP2M1,HADHA,AP1G2,AFTPH,NOP58,VTI1B,AP1M1,ATG9A,SEC13,CAV3,XPO1,PRDX3,TIMM29,SYNRG,FTH1,NUDT3,AP1AR,CCM2,UBE2M,HEXIM1,GGCX |
| 1.535e-02 | -4.18 | ELF3 (E74 like ETS transcription factor 3) | protein interactions | 1999 | 54 | 23 | 19454 | 5460 |
VPS72,TRIM24,GANAB,CORO1C,RPL6,MYC,CREBBP,CALR,NFKB1,AR,MYO6,CBR3,TAF9,XRCC5,EP300,JAK1,GRPEL1,SOX9,ISG15,JUN,NFE2L2,MED23,UBE2M |
| 1.535e-02 | -4.18 | EPM2A (EPM2A glucan phosphatase, laforin) | protein interactions | 7957 | 54 | 23 | 19454 | 5460 |
SQSTM1,HAPSTR1,PTGES3,PYGB,MCMBP,CCT5,STBD1,PSMC3,HEXIM1,TOPORS,PSMB1,UBE2N,AIP,STUB1,SRPK2,RPL10,PPP1R3C,TOMM70,PPP5C,PSMD4,ANKMY2,COX5A,BECN1 |
| 1.535e-02 | -4.18 | IPO11 (importin 11) | protein interactions | 51194 | 151 | 55 | 19454 | 5460 |
OPRM1,GPR17,CUL3,CALU,UBE2H,UBE2E3,CHRM4,EIF4A3,RAN,TUBA1B,LMBR1L,S1PR4,SCN2B,VIRMA,APLNR,FBXO22,EIF4A2,PRDX2,CFTR,CDC42,ATG16L1,FAM234A,STOM,P2RY12,DDX5,DR1,VIPR1,HSPA8,CD40,TACR3,SLC15A1,NPTN,CCR6,XPO1,UBE2E2,BRD3,HNRNPD,RHOG,MUL1,PHB1,RPL12,RPRM,CACYBP,PRNP,TRAF2,LPAR6,COMTD1,ADORA3,CYB5B,BZW2,TFCP2,SIGLECL1,UBE3A,EFNB1,KRAS |
| 1.535e-02 | -4.18 | CYFIP2 (cytoplasmic FMR1 interacting protein 2) | protein interactions | 26999 | 151 | 55 | 19454 | 5460 |
EPHA4,COX7B,RIGI,HS2ST1,COMTD1,ARHGAP12,MGARP,PDHA1,AQP3,HOMER3,RAC2,PLG,ZNF511,NYAP2,SPTAN1,ILVBL,COPS5,YWHAG,YWHAH,RHOG,SMAD4,SNRNP70,AGR2,NCK1,SMDT1,YWHAB,BAP1,RPA3,VIPR1,HSPA8,PSMA3,MTDH,FXR2,STAU1,WASF3,PACSIN3,SPTBN1,ATG16L1,BET1,RPA2,FGFR1,YES1,SRC,NCKAP1,VIRMA,ESR2,FGFR1OP2,SFN,MCM3,CCDC22,YWHAZ,TYROBP,NTRK3,OXTR,UBE2H |
| 1.538e-02 | -4.17 | THOC2 (THO complex subunit 2) | protein interactions | 57187 | 173 | 62 | 19454 | 5460 |
CUL3,MYC,CHTOP,LMNB1,ZCRB1,FYTTD1,RBBP8,UBE2H,THOC6,PDCD4,EIF4A3,CCNF,PTEN,APEX1,VIRMA,ZC3H14,MRPL12,MAP2K1,RPA2,SIRT7,PML,DDX39B,EEIG2,RPA3,THOC3,RAMAC,TTC1,FBXW7,STAU1,KDM1A,UFL1,AATF,ZC3H15,DDRGK1,SNRNP70,DDX23,SMAD4,BRD3,MED4,ALYREF,EED,THOC1,COG1,PLEKHF2,KIF1C,TP53,TPD52,RAF1,BUD23,TOP3B,LGR4,ZMYM3,DDX39A,ACADSB,SURF4,NUPR1,DHX9,ZC3H11A,ASF1A,CAMK2G,RIGI,POLDIP3 |
| 1.538e-02 | -4.17 | MALSU1 (mitochondrial assembly of ribosomal large subunit 1) | protein interactions | 115416 | 173 | 62 | 19454 | 5460 |
TFB1M,DCTD,MRPS18A,LMO3,MRPL12,RBMS2,NDUFAB1,MRPL10,RPL27A,MRPL20,CHMP2B,MRPL40,MRPL41,MRPL57,MRPL17,GFM1,GNRH1,BOLA3,MCAT,CIRBP,PCCB,NTAQ1,MRPL16,CUL3,MRM2,PMPCA,MTG2,MYC,ZMYND19,RPL19,RPL10,RPL13A,MRPL23,MRPL13,MTG1,MRPL53,MRPL51,GFM2,METTL15,GTPBP8,MRPL11,JPH4,MRPL47,HNRNPDL,RPL17,MRPL22,CHDH,TRIM63,PC,SRSF7,MKLN1,MRPL52,MRPL18,HNRNPA1,MRPL9,GRSF1,MRPL24,RBM42,MRPL50,PRR3,SYNCRIP,SSBP1 |
| 1.538e-02 | -4.17 | Hsp70 protein binding | molecular function | GO:0030544 | 51 | 23 | 18094 | 5411 |
DNAJC8,DNAJC10,CDK1,DNAJB6,BAX,RPS3,CYP1A1,STUB1,PACRG,NUP62,FGF1,DNAJC2,DNAJB2,PPID,ST13,DNAJB9,TFRC,MVD,HIKESHI,GPR37,CDKN1B,TTC4,METTL21A |
| 1.541e-02 | -4.17 | autophagy of mitochondrion | biological process | GO:0000422 | 60 | 26 | 18204 | 5365 |
ATG7,GABARAPL2,RB1CC1,MAP1LC3B,BECN1,RIMOC1,GABARAP,PHB2,FIS1,RETREG1,FUNDC2,WDR45,FUNDC1,ATG4C,ATG9A,SQSTM1,ATG4A,FBXO7,TP53,ATG3,GABARAPL1,TAFAZZIN,CTSK,MAP1LC3A,FBXL4,USP30 |
| 1.541e-02 | -4.17 | glycogen metabolic process | biological process | GO:0005977 | 60 | 26 | 18204 | 5365 |
GNMT,IL6ST,PHKG1,GYS1,PYGB,PPP1R2,WDR45,COMT,RB1CC1,PTGES3,AKT2,PHKB,AKT1,GSK3A,PPP1R1A,PPP1CC,GABARAPL1,LEPR,STBD1,UGP2,PPP1CB,PHKA1,ATG3,PYGM,GBE1,PPP1R3C |
| 1.546e-02 | -4.17 | APOBEC/CMP_deaminase_Zn-bd | interpro domains | IPR016192 | 13 | 8 | 18521 | 5414 |
APOBEC3C,APOBEC3F,DCTD,APOBEC3H,APOBEC3D,APOBEC3G,APOBEC3A,APOBEC3B |
| 1.546e-02 | -4.17 | NUDIX_hydrolase_CS | interpro domains | IPR020084 | 13 | 8 | 18521 | 5414 |
NUDT5,NUDT1,NUDT18,NUDT12,NUDT2,DCP2,NUDT4,NUDT3 |
| 1.546e-02 | -4.17 | LRP6 (LDL receptor related protein 6) | protein interactions | 4040 | 120 | 45 | 19454 | 5460 |
ST8SIA4,EDF1,SOST,CSNK1A1L,CSNK1A1,WNT10B,LMBR1L,ST8SIA5,CCNF,GXYLT1,CCL1,SEC61B,GSK3A,RHOJ,TENT4A,CKLF,VIRMA,PRSS37,CHST9,GGH,CMA1,RHOB,TAFAZZIN,SDF2L1,LRP6,KLK5,KRAS,PI15,LGR4,CBLN4,CLEC2B,TLNRD1,NCR3,ETV6,GJA1,CAV1,TLR1,KLK3,CFC1,GAS8,CTNNB1,DKK1,SCGB1D1,TRAF6,ST3GAL4 |
| 1.551e-02 | -4.17 | negative regulation of cell cycle | biological process | GO:0045786 | 381 | 132 | 18204 | 5365 |
MIR29C,PTEN,CCL2,MAD2L1,NPPC,NHERF1,NABP1,CDKN1A,MACROH2A1,PRPF19,CDC5L,PML,MIR16-1,CACNB4,H2AX,CRADD,ZNF655,PRMT2,CDK5RAP3,DCUN1D3,RB1,IK,BTG3,MIR424,BUB3,NEK2,ACVR1,NAE1,BAZ1B,FZD3,CCNF,CTDSP1,PSMG2,CCND1,DLG1,BRINP3,TNF,CRLF3,IL10,OVOL1,SPC24,NPR2,FBXO31,CTNNB1,DUSP1,RPA2,SOX2,GMNN,FAM107A,TRIM37,RINT1,TOPBP1,HEXIM2,CDK5,BCL6,NUF2,NOP53,HINFP,RHOB,RNF167,RPL26,TOM1L2,MIR137,RBBP8,MIR638,FBXO7,MAD2L2,CHMP2A,RAD21,NDC80,ZBTB17,TNKS,BABAM1,MAD2L1BP,CDKN2D,MIR195,TPRA1,EZH2,MIR29A,MIR193A,CDKN1B,MDC1,HTRA2,KLHL22,BTG2,RGCC,BRCA1,MIR711,SUV39H1,GPNMB,CHMP4C,MIR503,UFL1,NBN,PPP1R10,RPS27L,MIR21,CDC73,INHA,DTL,MDM2,MIR873,ZNF207,NLE1,BRINP1,GNB1L,MIR133B,TP53,CDK2AP2,IER3,TOM1L1,NUPR1,MIR15A,BTG1,VPS4A,FZR1,CDC20,RAD1,SMARCA5,CDK1,LILRB1,TRIM35,BRINP2,AURKAIP1,PTPN11,MIR10A,HEXIM1,KLF4,BTN2A2,JADE1,CDK6,CTDSP2 |
| 1.555e-02 | -4.16 | regulation of hemopoiesis | biological process | GO:1903706 | 425 | 146 | 18204 | 5365 |
DUSP10,BATF,AGER,GABPA,ISG15,FCGR2B,TESC,FBXW7,C1QC,KLF10,ACVR1B,BCL6,PPP3CA,HMGB1,SYK,PITHD1,GPR171,TOX,IL2RG,MIR145,TESPA1,CTNNB1,SKIC8,IL10,VSIR,ADIPOQ,TNF,EP300,ACTB,NOTCH2,CD2,NFKBIA,CTLA4,RHOH,CARTPT,TRIB1,SOD1,IL2,CCR2,TGFBR2,IRF4,MIR221,EEIG1,CCL19,SNAI2,LDB1,NDFIP1,MIR222,NLRP3,TRAF6,XBP1,PRKCA,RB1,BAD,TMEM176A,RAG1,CCR1,TOB2,IL15RA,ING5,STAT1,IRF7,FOS,HCLS1,IL2RA,IL5,RNF41,TLR4,KLHL25,GPR137,SMARCE1,CDK6,FGL2,HAX1,BTN2A2,LILRB1,FOXP3,TMEM176B,CD83,CCL3,PNP,IL18,PRDX2,NKAP,SASH3,ACTL6A,JUNB,BGLAP,CD86,CREB1,SFRP1,MITF,MYC,HOXB8,TNFAIP6,IFNG,TCIM,MMP14,IL12B,SOS2,TLR3,MIR223,FOXP1,ACTL6B,LILRB4,INHA,PTN,CDC73,CTNNBIP1,CD4,MIR30B,IFNA2,MIR21,CD46,FAXDC2,IL4,IRF1,TCTA,ZBTB16,SOCS5,RUNX1,PIK3R1,SMARCD3,TLR9,DROSHA,UBASH3B,MEF2C,IL7,CD28,B2M,TFE3,CBFB,CD80,IL23A,SMARCB1,MEAF6,RC3H2,WNT10B,IL34,PRELID1,IL15,IFNB1,TYROBP,FBXO7,PRMT6,LGALS3 |
| 1.556e-02 | -4.16 | positive regulation of hydrolase activity | biological process | GO:0051345 | 466 | 159 | 18204 | 5365 |
IFT57,MCL1,CCL1,RHOG,HTRA2,RGS10,RGP1,PSME2,MIR21,ARL6IP5,RPS27L,CXCL13,NTRK3,IFI16,PPARG,PRELID1,BCL2A1,SIPA1L1,AGAP1,APOC2,GPR65,ITK,MEF2C,EZH2,RALGAPA2,PMAIP1,LPAR2,AGAP2,HSP90AB1,NCSTN,RGS6,HSPD1,BCL10,HTR2A,ADRA1A,USP6NL,FGFR1,PDCD5,PPP1R12A,CCL3,FAM162A,PSENEN,CD200,THY1,FASLG,PLCB2,PHB2,CCL11,CCL8,MMUT,EPHA4,TBC1D25,IFNG,EFNA3,CCL5,TNFSF10,LPAR1,TIAM1,ACVR1C,RGS1,DAPK1,CD86,GNAQ,MIR15A,CCL17,ROCK1,MYC,FERMT2,ITGA6,BAX,GPIHBP1,CLEC7A,SFRP1,FAS,S1PR4,CCL25,NLRP3,KIT,TBC1D5,PSME1,ANP32B,ARHGAP25,CCL21,ODAM,MIR17,TBC1D17,CTSD,TBC1D16,HSPE1,CLDN3,FIS1,CCL19,PLAA,NR1H2,CAV2,PLA2G5,BCL2L1,PIP5K1A,RASGRP2,TBC1D13,JAK2,SEMG2,CCL2,CCL4L1,BAD,TBC1D10C,DAP,NLRP2,CCL18,CRADD,TBC1D4,AKT1,AIFM1,EPHA2,CLDN4,TNFSF15,CCL23,PKP4,CD40,MIR205,SYK,CORO1C,MAPRE2,HMGB1,NLRP1,CCL20,AGER,KHDC1,C9orf72,HRAS,PYCARD,TANK,NKX3-1,S100A10,S100A8,CX3CL1,SNX18,SMAD3,TAX1BP3,XCL1,MUL1,BOK,ROCK2,APH1A,DDRGK1,TNF,TBC1D1,ZC3H15,VSIR,CCL24,CYFIP2,PHB1,RPS3,EGLN3,AVPR1B,BAK1,PCNA,CTSK,RAP1A |
| 1.557e-02 | -4.16 | postsynaptic specialization | cellular component | GO:0099572 | 345 | 119 | 19108 | 5553 |
GRM1,CAP2,DROSHA,GABRA2,DLG1,NTRK2,GABRB2,GRIK1,EPHA4,IQSEC1,LIN7B,CTNNB1,BAALC,ZDHHC15,SYN3,KPNA1,USP8,SPOCK1,DLG4,ARF1,CHRM1,KCNB1,LRRC4,HSPA8,ADD2,EIF3E,PPFIA2,FLRT3,SIGMAR1,HOMER1,SH2D5,CHMP2B,SPTBN1,GPHN,PICK1,CAMK2N1,SRC,CDK5,DLGAP4,RPL7,DRP2,PRRT1,DGCR8,IGSF11,TNIK,DISC1,RPL8,KCNH1,DNM2,RPL6,P2RY1,LRRTM3,FABP5,LRFN3,INSYN2B,MAP1B,ATP1A1,PHB2,SLITRK1,LRRC4B,HNRNPH2,DAPK1,NPTN,CTNND1,RPL12,KCND3,SIPA1L1,RNF10,ABHD17A,LRRTM1,PTEN,PDE4B,LRRTM2,DLG3,GRIA1,CACNG3,INPP4A,CHRNB2,RTN4,MTMR2,SLC8A1,GRIA2,NLGN2,CLSTN3,NLGN1,BMPR2,RHEB,GRID1,PAK2,FAM81A,PAK6,PKP4,CDK5R1,CPEB1,ADD1,SYNDIG1,NETO1,HTR5A,RPS3,TIAM1,RPS13,LIN7C,LHFPL4,HOMER3,GNG3,SEMA4C,HNRNPD,EPS8,TMEM108,RPLP0,INSYN2A,RPS14,KCND2,NETO2,INSYN1,PRNP,RGS7BP,RPL10A,GLRB |
| 1.558e-02 | -4.16 | Kelch | smart domains | SM00612 | 57 | 23 | 9717 | 2575 |
IVNS1ABP,KLHDC8A,KLHL12,KLHL32,KLHL15,KLHL25,KLHL26,KLHDC8B,KLHL1,KLHL22,KLHL23,KLHL7,IPP,KLHL24,KLHL3,KBTBD6,KLHL28,KBTBD3,CCIN,ENC1,KBTBD13,KLHL9,KBTBD2 |
| 1.560e-02 | -4.16 | response to nutrient levels | biological process | GO:0031667 | 485 | 165 | 18204 | 5365 |
TYMS,DAP,OGG1,LTA,IL15RA,EIF2S1,RNF152,PRKCB,MAP1LC3A,SH3GLB1,LRAT,STAT1,CDKN1A,PCSK9,CCL28,CIDEB,GAD2,FOLR1,NPPC,CXCL10,FOS,ACAT1,CARTPT,CYP1A1,CNR1,BECN1,PICK1,STK26,EIF2AK2,FAS,G6PD,RHEB,CYP1B1,CBL,TBC1D5,GNAI2,LAMTOR1,PPM1D,TMEM126B,ADRB3,XBP1,GHRL,PRKAB1,KICS2,GPT,TFRC,GPX1,SEC13,SESN3,TRIM32,GH1,MAP1B,VDR,CTSK,GLUL,SRSF2,IL1A,PARP2,STC1,EP300,ALB,SLC2A1,ADIPOQ,TNF,UCP2,MBD3,RNF167,CREBBP,PROX1,AMELX,ADRB2,ITGA2,GABARAP,FOXA3,ATF3,FOLR2,FBP1,AKT1,DELE1,MIOS,HFE,RALB,KLF10,CD40,SPP1,GCLC,RMI1,SOX2,NPY,FAM107A,TMIGD1,PRKAG1,CDKN2D,BMPR2,PMAIP1,UCN,FKBP1B,GABARAPL1,SLC38A2,FBXO22,SAR1B,CYP27B1,FGF23,MKKS,RRAGB,ALPL,CNTN2,NFE2L2,EPO,SLC6A4,CSNK1A1,SLC16A1,SP1,IFI16,AQP3,LIPA,PPARG,SUV39H1,SESN2,SLC38A3,YWHAZ,NQO1,PCK2,ATG7,TSPO,GABARAPL2,HSPA5,STK24,IMPACT,SOD2,BGLAP,GNPAT,FLCN,SFRP1,IGF1R,LAMP2,HNRNPA1,TP53,HCRT,KCNB1,YWHAG,MDM2,RRAGA,ACVR1C,F7,PPARA,TFEB,WDR45,ATF4,DDIT3,LEP,ADRB1,LDLR,SGIP1,BCL10,GHR,SRC,MAP1LC3B,HSPA8,CYP26A1,PRL,CSH1,UGT1A1,SST,COMT |
| 1.560e-02 | -4.16 | GATAD2A (GATA zinc finger domain containing 2A) | protein interactions | 54815 | 208 | 73 | 19454 | 5460 |
BTF3L4,CSNK2A1,DPY30,BRD3,KPNA1,SNRNP70,GATAD1,EED,MYBL2,SRSF1,SIN3A,H2AZ1,HMG20A,ZBTB2,BRMS1L,SHPRH,SAP30,SOX2,MAP1LC3B,H2AX,TP53,MTA3,RAF1,EIF1AX,MTA2,RBPJ,EZH2,STMN2,SSRP1,MSH6,RIGI,MEPCE,PHF1,KPNA2,RUVBL1,CDK2AP2,ASF1A,RBBP7,H3C1,ZNF592,KRAS,PSMA5,RUNX1,FBXO44,ZNF687,CREBBP,SUGP1,MYC,SMARCA5,FAM219A,SPOP,INTS12,MACROH2A1,CSNK2B,ZNF330,CCNF,DEK,RBBP4,SNRNP40,KLF12,ATG16L1,EIF4B,HEXIM1,RPA2,KLF3,RNF113A,SYVN1,APPBP2,PML,NLE1,RPA3,BAP1,MBD3 |
| 1.561e-02 | -4.16 | RND3 (Rho family GTPase 3) | protein interactions | 390 | 269 | 92 | 19454 | 5460 |
WDR6,PPIA,SPTAN1,PPFIBP1,OLR1,CTNNB1,PIK3R1,YWHAB,ARHGAP5,EFNB1,CDK5,AHCYL1,SSRP1,RBPJ,RPN1,STIM1,FAM83B,PSMD1,MRPL16,NIBAN2,PKP4,SFN,SLC7A11,SLC38A1,LAMTOR1,CKB,MYO6,TXNL1,ITGAV,EMC1,ETF1,USP6NL,NOTCH2,CTBP1,SLC39A10,ADD1,CDCA3,ACTA2,TMPO,CAV1,SPPL3,TPM3,RELL1,OSBPL8,SLITRK5,SLC2A1,ESYT1,NOS1AP,EMC2,SNAP23,PALM2AKAP2,DLG1,SLC6A8,CTNND1,NEDD8,AKAP12,SRPRB,CCDC47,ANGPT1,TFRC,BMPR2,GANAB,VAMP3,NECTIN2,ROCK1,FERMT2,SH3BP4,SRC,TMOD3,YES1,DEPDC1B,ARHGAP21,SLC25A1,ATP1A1,EPHA2,ATP1B3,ITGA2,SOD1,YKT6,PIK3R2,FTSJ1,FBXW7,CDC42,CNP,CFTR,SPTBN1,SNRPN,LEMD3,JUP,SLC12A2,PICALM,DDX4 |
| 1.562e-02 | -4.16 | negative regulation of endocytosis | biological process | GO:0045806 | 77 | 32 | 18204 | 5365 |
LRRTM2,CSK,MIR185,NR1H2,PCSK9,APOC2,PIP4P2,PACSIN3,ATG3,LGALS3,SDCBP,ADIPOQ,CD47,LRRTM1,CAV1,PLSCR1,PICALM,PSEN1,DLG4,ARF6,SNX33,FCGR2B,MIR92B,TLR2,SNX3,LILRB1,SCAMP5,MIR205,ITGAV,HMGB1,MIR17,MTMR2 |
| 1.566e-02 | -4.16 | TRAF7 (TNF receptor associated factor 7) | protein interactions | 84231 | 117 | 44 | 19454 | 5460 |
IFT57,CD2BP2,HOXB1,TOP3B,ZNF263,TP53,PFDN1,RIGI,KRAS,ZNF365,BAG2,POU5F1,UBE2D1,TRAF6,KXD1,CYTH4,SPPL3,RGCC,NELL2,RAC2,HRAS,TMEM174,CDC42,RALYL,ATG16L1,MAPKAPK5,ATG4C,SKP1,UBE2K,OIP5,ARRDC3,LCA5,PFDN2,PFDN4,FBXW11,FGFR1OP2,EMILIN1,CUL3,UBE2L3,MAP3K3,RRAS2,SYBU,TRAF7,TRIM44 |
| 1.566e-02 | -4.16 | HSP90AB4P (heat shock protein 90 alpha family class B member 4, pseudogene) | protein interactions | 664618 | 117 | 44 | 19454 | 5460 |
TTC9C,YES1,PPP5C,CDK9,DUSP3,HSP90AB1,FOLR1,RAB28,EEF1AKMT3,LRRC28,DCAF4,FKBP4,RPS6KA4,ANAPC4,STK11,HSP90AA1,STYK1,REN,DNAJB6,PRKX,AKT3,PRKACB,CCIN,CDK20,FBXL4,PTGES3,TKTL1,PRPS1,FKBP8,BAP1,RUVBL2,TESK2,RNF146,PPT1,CHMP4C,PLD3,TMEM184B,LIAS,CDK4,MREG,AGO1,CDK7,DET1,SMYD3 |
| 1.566e-02 | -4.16 | FBXO11 (F-box protein 11) | protein interactions | 80204 | 117 | 44 | 19454 | 5460 |
BCL6,SKP1,STAU1,SNX24,ZNF692,MMADHC,CTBP1,CFTR,HSPB6,JUNB,MBL2,STAT2,USP16,BAHD1,DTL,THAP7,TFG,RIGI,KRAS,FAM168A,FBXO11,MRFAP1L1,ADAMTS1,IKZF5,AURKAIP1,NECAP2,TP53,RAF1,RBM12,ZNF263,SNX18,COPS7B,C1QTNF1,COPS2,EED,PLAC9,TRAF3IP3,KCNA2,AIP,FOSL2,HDAC6,COPS5,WWP2,MARCHF5 |
| 1.567e-02 | -4.16 | unsaturated fatty acid metabolic process | biological process | GO:0033559 | 103 | 41 | 18204 | 5365 |
FADS2,AKR1C1,PTGDS,AKR1C2,CYP4F8,ELOVL3,ELOVL7,HPGDS,CYP2C9,ELOVL6,GSTP1,ABHD6,CYP2C18,PNPLA8,DEGS1,GPX1,PTGES,ELOVL1,MGST3,PLA2G4B,DECR2,COMT,MIF,CYP2D6,CYP4F12,GPX4,PTGES3,CYP1B1,ABHD12,GSTA1,SCD5,GSTM2,PLAA,AKR1B1,ACOX1,EPHX1,ELOVL4,ACOT8,CYP2C8,CYP1A1,CYP2F1 |
| 1.567e-02 | -4.16 | cellular lipid metabolic process | biological process | GO:0044255 | 914 | 299 | 18204 | 5365 |
PIK3R3,PRKD3,CRYL1,DHRS7,PIP4P2,HSD17B10,OSBP,ST6GALNAC3,GK5,CERS6,PLSCR3,SGMS1,HYCC1,LIAS,INPP5E,CPT2,PGAP2,GPX1,ACADS,CPT1B,GSTP1,GSTM2,AMACR,PEX13,PLA2G15,GAL3ST1,GDPD3,ADTRP,HACD4,RBP2,PCCB,MPDU1,NR1H2,ILVBL,PCSK9,PLA2G5,PIP5K1A,PTEN,UGCG,ACACA,B3GALT2,SPTSSA,ACER3,SCPEP1,TECR,PLA2G12A,KIT,ALG11,DHRS7B,EHHADH,GPX4,XBP1,DOLK,ETNK2,CYP1A1,MVD,CYP2C8,BECN1,HYCC2,PLAA,MMUT,ABHD4,HACD2,CYP4F8,ACSL4,FITM2,ACAA2,CDIPT,PLA2G4B,PGAP3,PTGES,AUH,ADIPOR2,DEGS1,SOCS2,MTMR6,HEXA,BAX,ABHD6,AGPAT1,INPP5K,AGPAT5,MBLAC2,FUT1,CYP26A1,GGPS1,MIF,ISYNA1,MORC2,PPARA,CYP2F1,GDE1,GAL3ST4,SOCS4,ACADSB,IMPA2,ELOVL7,PHYH,CRAT,SOCS3,DHRS4L1,CAV1,ST3GAL1,SLC25A17,SLC35C1,NUS1,PRKAG1,NEU1,CAV3,ACOT6,SMPD2,NUDT19,ACP6,PIGW,CD36,PNPLA8,MGST2,HACD3,ABHD12,BRCA1,PCK2,PLCB1,HTRA2,ORMDL1,CYP2D6,ZMPSTE24,SOCS5,CYP4F22,ETFA,LPCAT3,SRD5A3,PLPP6,B3GALNT1,MTM1,HADH,B3GALT4,ST3GAL2,EPHX1,DHRS4,OCRL,CERS2,PPT1,GPAA1,MCAT,PLAAT3,GALC,ADIPOQ,PRKAB1,STAR,FA2H,GPAM,RDH12,ABHD16B,MSMO1,MTMR12,RDH11,CISH,CERK,PCYT1B,ORMDL3,CYP4F12,CYP3A5,GK2,DPAGT1,ADIPOR1,PRDX6,AKR1B1,DPM2,ITGB8,ABHD5,HSD17B6,FITM1,CBR4,LRAT,SPHK2,ELOVL6,CYP2C9,HPGDS,SDR16C5,INPPL1,PLP1,ECHDC1,ALOX5AP,PTPMT1,ELOVL1,FDFT1,FUT9,TAFAZZIN,RDH10,PIGA,CHKB,SELENOI,RARRES2,ST8SIA5,CYP1B1,SGMS2,GSTM4,MECR,PLSCR1,ACAT1,ACOT8,ALDH1A3,PIP4K2C,VPS54,HADHA,FIG4,PAFAH1B1,ELOVL3,PIGC,PIK3CA,FADS2,DECR2,SERINC1,GNPAT,PGAP4,ACBD7,CYGB,LYPLA2,GPIHBP1,PEDS1,LARGE1,SCD5,ACSS2,PLPP4,PTGES3,PDSS2,TMEM38B,CRABP2,UGT1A1,COMT,NDUFAB1,MTMR2,VAC14,PIK3CG,INSIG2,DHRS3,LEP,HSD17B8,PLCB2,AIG1,B3GALT1,SPTSSB,ABCG2,RETSAT,ST3GAL4,PIP4P1,INPP4A,ADH1B,IP6K1,PTPN11,SACM1L,PNPLA4,PLPPR1,CYP4V2,ETFB,HACD1,B4GALT4,FABP5,MECP2,ABHD2,CLN8,AKR1C2,PTGDS,AKR1C1,OSBPL8,MGST3,LYPLA1,PLAAT5,HEXB,HMGCS1,CYP2C18,SLA2,HDHD5,SLC30A5,GSTA1,B4GALT3,ADH1A,SESN2,PIGK,TNFAIP8L3,KDSR,PIK3R1,BPNT2,ALG2,AGK,ST3GAL5,PIK3R2,NUDT7,PGS1,TAMM41,B4GALT6,PTDSS1,TLCD3B,ST8SIA4,ELOVL4,LIPA,ACOX1,PPARG,PIGY |
| 1.568e-02 | -4.16 | positive regulation of cell-cell adhesion | biological process | GO:0022409 | 328 | 115 | 18204 | 5365 |
PDCD1LG2,CYRIB,RHOH,DPP4,CCR2,IL2,TGFBR2,CCL19,EFNB1,AIF1,NLRP3,TRAF6,XBP1,CHST2,CCL21,BAD,RAG1,TNFRSF14,IL2RA,ICOS,CCL2,JAK2,PYCARD,AGER,DUSP10,EMILIN1,CCR7,BCL6,AKT1,IL1B,HMGB1,SYK,CD1D,PPP3CA,SOX2,NCK1,RPS3,SELENOK,TFRC,YES1,IL2RG,TESPA1,GPAM,IL1A,CX3CL1,XCL1,IL10,EP300,ACTB,IGF1,VSIR,TNF,CD209,MIR30B,MIR21,CD4,LILRB4,CD81,CXCL13,CD46,PRKCQ,ZBTB16,IL4,JAK1,SMARCD3,F11R,SOCS5,RUNX1,IL7,IL23A,CD28,B2M,CD80,CBFB,SMARCB1,WNT10B,CAV1,IL15,EPO,FLOT1,THY1,SMARCE1,CD40LG,LEP,KLHL25,IL6ST,ST3GAL4,BTN2A2,PTPN11,FOXP3,SRC,IL12A,CD274,HTR2A,BCL10,HSPD1,LILRB1,DHPS,NKAP,ACTL6A,SASH3,CD83,IL18,PNP,CD86,CSK,IL21,IL6,IFNG,SLC7A1,IL12B,ACTL6B,CCL5,CD47,PIK3CA |
| 1.569e-02 | -4.15 | PLOD2 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 2) | protein interactions | 5352 | 170 | 61 | 19454 | 5460 |
C1QTNF1,TMPO,OS9,SWAP70,SEC23A,RPL24,FKBP4,CBL,USP15,PDIA3,KARS1,FAM20C,HNRNPA1,XPO1,PPIB,HNRNPK,ADIPOQ,SAR1B,HNRNPDL,FAF1,CCT8,RUVBL2,EMC2,RAF1,UBL4A,SUPT5H,GGCT,CBLN4,RAB14,CTSB,ATP5F1B,ACTB,RHOJ,APEX1,LMBR1L,CCNF,PAPSS2,GANAB,SEC61B,CALU,CUL2,PAPOLA,SAMHD1,ATP5F1A,GMPS,EMC1,PYGB,UGP2,HSPA5,BAP1,DNAJC3,RPA3,TMEM106B,HNRNPH2,GPX4,RPA2,LMNA,JUP,NUFIP2,ARHGAP1,CDC42 |
| 1.571e-02 | -4.15 | myosin phosphatase activity | molecular function | GO:0017018 | 76 | 32 | 18094 | 5411 |
DUSP26,PPM1K,PPP5C,SSU72,PTEN,PPP1CC,DUSP6,PPP2CB,PPP1CB,PPM1D,DUSP1,DUSP22,DUSP19,UBLCP1,PPTC7,CTDSP1,PPM1M,DUSP10,PTPMT1,CDKN3,DUSP21,CTDSP2,PPP4C,PPM1B,RPAP2,SSH3,PPP3CA,PPM1G,DUSP18,DUSP9,DUSP3,DUSP14 |
| 1.573e-02 | -4.15 | tau protein binding | molecular function | GO:0048156 | 43 | 20 | 18094 | 5411 |
FKBP4,HSP90AB1,BAG2,PICALM,ACTB,STUB1,AATF,HDAC6,PPP2CB,S100B,ROCK2,ROCK1,PPP5C,GSK3A,EP300,CLU,DYRK1A,CDK5,HSP90AA1,SMAD2 |
| 1.575e-02 | -4.15 | PNMA1 (PNMA family member 1) | protein interactions | 9240 | 189 | 67 | 19454 | 5460 |
MRPL11,PNMA5,ZNF581,TNNI1,PNMA2,SCAND1,GRAP2,HGS,APTX,TCEA2,RBM41,PSMA1,SEMA4C,FEM1C,POLL,PCGF6,POLDIP3,ENKD1,USP2,SHC3,STAMBPL1,SSX2IP,ZNF688,ACTA2,TTC9C,CCAR2,PRPF18,TSPYL4,CHIC2,FAM161A,EHHADH,MRPL10,LMO3,CFTR,ATP5PO,SDCBP,VAV2,CTDSP1,DCTN4,LSM2,CARHSP1,MACIR,ARHGEF6,FXR2,CHMP2B,ATP6V1G1,PRPF31,ZCCHC12,NTAQ1,SNRPB,TTC23,FAS,NIF3L1,YWHAZ,FAM107A,PNMA1,ACOX1,TMSB4X,SCNM1,HAPLN2,MRPL23,ABHD17A,ACTB,RPP25L,RPP25,SNRPB2,EAF2 |
| 1.575e-02 | -4.15 | HEXB (hexosaminidase subunit beta) | protein interactions | 3074 | 57 | 24 | 19454 | 5460 |
SQSTM1,ABCE1,CSNK2B,TMEM106B,BAP1,SOD1,RPL22,EIF2D,TENT5C,VCPKMT,UBR7,TUFM,CSNK2A1,GTF3C4,CUL3,HEXA,TMEM14B,TSNAX,HEXB,PDCD10,RARS1,HNRNPH3,MAP2K1,STIM1 |
| 1.575e-02 | -4.15 | PDCD7 (programmed cell death 7) | protein interactions | 10081 | 57 | 24 | 19454 | 5460 |
METAP2,FEZ1,ZMAT5,SNRPD3,PRNP,SNRPB2,RPL10,FBXO7,H2BC9,SNRPB,ZCRB1,POU5F1,RIT1,KRAS,MRPL22,SNRPG,ATG16L1,NUP62,RAF1,SNRPN,DDX39A,EIF3J,LSM2,SNRPE |
| 1.575e-02 | -4.15 | CTNNA2 (catenin alpha 2) | protein interactions | 1496 | 57 | 24 | 19454 | 5460 |
SAPCD1,CDH8,JUP,MAP2K3,CLEC2B,PPP2R1A,DUSP22,RAF1,UBE2A,EPHA4,G3BP1,LRRN4CL,RBBP8,FBXW11,CTNNBIP1,CTNNB1,TAX1BP3,MYC,NXPH3,ESR2,FZR1,SDHAF2,TES,CTNNA1 |
| 1.575e-02 | -4.15 | BDH1 (3-hydroxybutyrate dehydrogenase 1) | protein interactions | 622 | 57 | 24 | 19454 | 5460 |
HDAC6,P2RY10,LAMP2,ESR2,APLNR,ELK1,HNRNPL,AIFM1,HDAC11,AQP3,MGARP,QTRT2,HCST,LPAR6,SOX2,RAF1,SLC15A1,NPTN,TNF,CD80,THBS3,RNF113A,VIPR1,SLC39A9 |
| 1.575e-02 | -4.15 | SPI1 (Spi-1 proto-oncogene) | protein interactions | 6688 | 57 | 24 | 19454 | 5460 |
MECP2,IRF4,CREBBP,NFYA,NFKB1,ATF1,NONO,IRF1,CSNK2A1,RUNX1,MITF,CEBPE,SIN3A,IRF2,RB1,IRF8,JUN,GFI1,FBXW7,HDAC3,SSRP1,BCL6,PML,FOS |
| 1.575e-02 | -4.15 | ZNHIT1 (zinc finger HIT-type containing 1) | protein interactions | 10467 | 57 | 24 | 19454 | 5460 |
HINFP,ZNHIT1,ACTL6A,TP53,DMAP1,P3H1,H2BC1,GIT2,OTX2,LCA5,RUVBL2,RUVBL1,BCL6,MDFI,ACTL6B,ATG3,CRTAP,PSMG3,H2AZ1,VPS72,SH2D1A,CSNK2B,FZR1,MAD2L1 |
| 1.575e-02 | -4.15 | PRKCQ (protein kinase C theta) | protein interactions | 5588 | 57 | 24 | 19454 | 5460 |
CBL,C2CD2L,HSP90AA1,PRKCA,IKBKB,BCL10,CISH,CCNA2,LAMP3,YWHAG,CUL3,ZNF24,LAMP2,AKT1,RAB2A,PRKCQ,SELL,PRKCE,RASGRP3,PELI1,AKAP1,MSN,ICAM3,RPA3 |
| 1.580e-02 | -4.15 | Aryl Hydrocarbon Receptor | WikiPathways | WP2586 | 48 | 25 | 5310 | 1910 |
CD36,AIP,GCLC,MYC,CCL1,CYP1A1,KRAS,VEGFA,MAP2K1,NFE2L2,RB1,EP300,HSP90AA1,NFKB1,CDKN1B,NQO1,TNF,CYP1B1,HRAS,RAF1,PSRC1,CDKN1A,PLAGL1,SRC,HPGDS |
| 1.584e-02 | -4.14 | CDK2AP1 (cyclin dependent kinase 2 associated protein 1) | protein interactions | 8099 | 114 | 43 | 19454 | 5460 |
ATPAF2,MBD3,RPS15,HDAC3,SGF29,WDR77,PHF12,SRC,APEX1,VIRMA,RBBP4,NTAQ1,KPNA6,SMARCA5,ZNF687,PICK1,MRFAP1L1,MRPL22,PHF1,RBBP7,CDK2AP2,SAP30,SPG21,RAF1,MTA3,SH3GLB1,MTA2,EZH2,TMEM165,MYBL2,EED,GATAD1,SIN3A,ZBTB2,HMG20A,COPS7B,SHPRH,BRMS1L,DPY30,KPNA1,CBL,POU5F1,BRD3 |
| 1.584e-02 | -4.14 | MPZL1 (myelin protein zero like 1) | protein interactions | 9019 | 114 | 43 | 19454 | 5460 |
TNPO2,SFTPC,CTLA4,SIGLECL1,CRKL,VAC14,FHL3,PICK1,TOLLIP,TRIM63,KRAS,IFIH1,MED21,RHOG,PLAC9,RAB35,HRAS,RAC2,RHOH,ARF6,CAV1,DIRAS3,CDC42,ARL15,TMEM106B,HSPA8,EXOSC4,VIPR1,POLA2,STX7,PTPN11,RAB2A,HSD17B1,FBXO7,RHOB,LAMTOR1,AMIGO1,FZD4,GGT7,LGALS3,RHOJ,SRC,TECR |
| 1.588e-02 | -4.14 | SNARE | pfam domains | PF05739 | 13 | 8 | 17795 | 5224 |
STX12,STX16,STX7,STX6,STX1A,STX8,STX5,STX10 |
| 1.590e-02 | -4.14 | SPTBN2 (spectrin beta, non-erythrocytic 2) | protein interactions | 6712 | 145 | 53 | 19454 | 5460 |
APEX1,VIRMA,DAPK1,CTSB,ACTB,RHOJ,FBXO22,LAMTOR1,RHOB,DNAJC5,USP14,RAB2A,ADRB2,RHOU,BAP1,RPA3,SIRT7,RPA2,CDC42,PPP1CB,CLDN4,LMAN1,DIRAS3,CAV1,ARF6,RHOH,SPTAN1,RAB35,RHOG,SNRNP70,EXOC2,HDAC6,LAMP3,DPP4,LAMP2,RAB5C,UBE2A,FLOT1,KRAS,ASF1A,KGD4,ILF2,CCR1,SMARCB1,RND3,TFCP2,TFRC,CAPZA2,CHMP4C,SOX2,ACTR1A,TOP3B,RAF1 |
| 1.591e-02 | -4.14 | external side of plasma membrane | cellular component | GO:0009897 | 396 | 135 | 19108 | 5553 |
KCNJ3,FASLG,FCN2,IL2RA,CD209,CD40,THBD,CXCR4,EFNA5,BMPR1A,CD3G,PRND,ACKR3,CD86,FCGR2A,BTN2A2,LRRC24,TAS2R16,CCR7,HYAL2,CXCL9,B4GALT1,GRIA2,GHR,CXCL12,CD248,CD28,CCR3,KLRD1,TNFRSF9,LEPR,F2,GPIHBP1,CHRNB2,SLAMF9,CLEC12B,CAPN2,THY1,FCGR2B,CD226,CD59,RS1,AQP4,CD34,ABCG2,FOLR1,ALCAM,CCR4,IGSF21,CD9,CD1B,CD2,CD83,PRNP,PDCD1,CD79B,CD1E,CALR,CLEC6A,CTSB,CD1D,FOLR2,LY6G6C,FAS,SEMA7A,GLRA1,CXCR3,ATP6AP2,SERPINA5,TMEM123,CD36,CXCR6,F10,CXCL10,PDCD1LG2,LILRB1,TFRC,CD80,IDE,ITGA2,MOG,ADAM21,PCSK9,SELL,FCGR1A,TLR8,CCR1,GPC4,CD14,AZGP1,IL12B,DAG1,MICB,MBL2,LY6G5C,KLRC2,CCR5,IZUMO1R,TGFBR2,FCER1G,CTSK,CCR2,CXCR1,CCR6,CTLA4,CNTFR,TLR4,TNF,SLC38A1,IL2RB,TNFRSF14,CD1C,PLG,LDLR,ICAM1,B2M,ASTN1,CD1A,IL2RG,IL13,CD274,CLEC2B,CD4,ABCB1,ITGA6,CD40LG,CX3CR1,CDH13,FLOT1,CD200R1,IL6ST,ITGAV,KIT,HFE,ENPEP |
| 1.592e-02 | -4.14 | positive regulation of cellular catabolic process | biological process | GO:0031331 | 217 | 79 | 18204 | 5365 |
SQSTM1,PLEKHF1,TRIM5,ADRB2,C9orf72,WDR45,TFEB,TRIM21,MTDH,STK11,PPARA,SNX33,ABHD5,PAFAH1B2,IL1B,VDAC1,SH3BP4,RALB,HTR2A,PTPN1,RB1CC1,STUB1,HMGB1,TRIM34,ORMDL3,AKT2,TRIM8,TOM1,TRIM6,LACRT,ATG101,DAPK1,FLCN,SLC25A4,TP53INP1,TRIM32,SESN3,ROCK1,IFNG,PACSIN3,SNX18,GNAI3,TRIM68,ATG16L1,TNF,CCNY,IGF1,SVIP,TMEM59,PSEN1,TBK1,HSPB8,UFL1,PIP4K2C,BECN1,IL4,SESN2,BAG3,CSNK2A1,TRIM22,TNFRSF1B,TLR9,SLC25A5,TRIM23,BAD,BNIP3L,RGMA,GSK3A,RNF152,OPTN,PIM2,FURIN,APOC2,PCSK9,SH3GLB1,IFNB1,FBXO7,TICAM1,SUPT5H |
| 1.595e-02 | -4.14 | PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B) | protein interactions | 5495 | 205 | 72 | 19454 | 5460 |
IFI16,DCAF4L2,KARS1,PRPF19,DDRGK1,XPO1,IKBKB,MAGOH,ZDHHC15,COX4I1,PTK7,CDK6,GJA1,S100A8,PRNP,MIF,SPTAN1,FZR1,HSP90AB1,CCT7,POLE3,CACYBP,EGLN3,TP53,INSIG2,CCT5,TBK1,CSNK1E,FNTB,ISG15,NUPR1,CASK,LIPA,LPAR2,VDAC1,BPGM,SSRP1,PSMD14,SETD7,UBE2H,PRSS1,PAXX,OSGEP,RPS5,OAT,EIF4A3,CMTR1,CCNF,RPS9,MSN,RPS12,MACROH2A1,ARMC6,MAD2L2,VIRMA,SPTBN1,ELK4,BORCS6,FGFR1,VAV2,PPARG,CDK1,UBE2M,TIMP3,SOD1,PEBP1,RAB5A,NR1I3,ATP5F1E,EEF1G,UFL1,FBXL4 |
| 1.595e-02 | -4.14 | CTDP1 (CTD phosphatase subunit 1) | protein interactions | 9150 | 205 | 72 | 19454 | 5460 |
HMGB1,FBXW7,RADX,STK38,MED11,RPA3,RFC4,NUBP2,EP300,TCEA1,MED23,RPRD1B,MED31,SEC22B,WDR77,CDK7,ELP3,MED17,ARMC6,PRRC2A,VIRMA,CHP1,ERH,APEX1,POLR2B,SUCLG2,MAD2L1,CDIPT,SF3B6,POLR2F,GTF2F1,GTF2F2,CSNK2B,PRMT5,SYT2,ATG3,XPOT,DSN1,AKT1,NCAPG2,SNRPB,SAMHD1,IRF1,RFC5,GNL1,FGF12,AKAP12,RFC3,CHMP4C,CDK8,POLR2C,POLR2G,POLR2D,MED9,ARFGEF1,TOP3B,POLR2I,PPP1R18,NUF2,CDK9,POLR2L,EEF1AKMT3,SIN3A,COQ8A,GTF2B,MAGED2,EXOC2,SNRNP70,MED4,WWP2,UBXN6,CSNK2A1 |
| 1.595e-02 | -4.14 | ST14 (ST14 transmembrane serine protease matriptase) | protein interactions | 6768 | 205 | 72 | 19454 | 5460 |
LIPT2,CFC1,SPON1,EIF5A2,SMAD4,C1GALT1C1,RPL23,ITGA6,ELSPBP1,HRAS,PHB1,ZNF664,DIPK2A,LDLR,CHID1,SPINT2,ANKRD46,COCH,DNAJB9,SEMA3C,LMAN1,NETO2,TOP3B,TOR3A,CLEC2B,NDST1,DIPK1A,TMEM59L,SFTPC,ADAMTS1,CPE,TMEM39A,CDKN2C,AGA,RNASE4,KRAS,B4GALT7,TOR2A,FKBP2,UST,TUSC3,GALNT2,AKT1,GLT8D2,TAFAZZIN,STK11,GXYLT1,ST8SIA5,NECTIN2,FBLN5,OAF,DNASE1L1,B4GALT1,MGAT1,EFNA5,NOTCH2,IL6ST,GPC4,TMEM106A,TMX4,FEM1A,OGFOD3,PLAC1,MET,SERPINI1,FAM3C,TIMP3,VLDLR,SQSTM1,EGFL7,RAB5A,EMC1 |
| 1.595e-02 | -4.14 | ARHGAP15 (Rho GTPase activating protein 15) | protein interactions | 55843 | 21 | 11 | 19454 | 5460 |
KDM1A,PRNP,SMURF1,HACD3,TRIM27,BCAP29,CYB5A,ESYT1,ATG16L1,DHPS,PGRMC1 |
| 1.595e-02 | -4.14 | EID2 (EP300 interacting inhibitor of differentiation 2) | protein interactions | 163126 | 21 | 11 | 19454 | 5460 |
SMAD3,EP300,MAGED2,NDN,MAGEC2,EID2B,XPO1,SMAD4,MAGEH1,MAGEB1,SMAD2 |
| 1.595e-02 | -4.14 | TSNAXIP1 (translin associated factor X interacting protein 1) | protein interactions | 55815 | 21 | 11 | 19454 | 5460 |
UTP6,SPG21,GRAP2,HSPB1,TSNAX,CDC7,LZTFL1,CCDC186,PRPF18,UBE2L3,RIGI |
| 1.595e-02 | -4.14 | HHV8GK18_gp83 (K14) | protein interactions | 4961465 | 21 | 11 | 19454 | 5460 |
PTK7,CCDC126,ITM2B,CCDC127,CTNNA1,FAHD1,SACM1L,GALNT2,EMC10,SEC62,NCR3LG1 |
| 1.595e-02 | -4.14 | GALT (galactose-1-phosphate uridylyltransferase) | protein interactions | 2592 | 21 | 11 | 19454 | 5460 |
NFE2,GRPEL1,UBTD2,NRBF2,MYG1,SERTAD1,TMED9,NQO1,VAC14,ARPC3,NIF3L1 |
| 1.595e-02 | -4.14 | RAPGEF3 (Rap guanine nucleotide exchange factor 3) | protein interactions | 10411 | 21 | 11 | 19454 | 5460 |
DAPK1,RIGI,EXOC8,AP1M1,RAP1A,RAN,UFSP1,PNMA1,OARD1,RAP2A,RRAS2 |
| 1.595e-02 | -4.14 | ZNF641 (zinc finger protein 641) | protein interactions | 121274 | 21 | 11 | 19454 | 5460 |
ROCK2,KDM1A,ADD2,SRC,SCNM1,CHAMP1,CSNK1G3,LMO2,RBM12,LMO3,PRKACB |
| 1.595e-02 | -4.14 | ATF5 (activating transcription factor 5) | protein interactions | 22809 | 21 | 11 | 19454 | 5460 |
DISC1,TTR,CEBPE,GABBR1,CCND3,GIT2,CEBPG,EP300,HAPSTR1,FBXO7,DDX39A |
| 1.595e-02 | -4.14 | ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2) | protein interactions | 114794 | 21 | 11 | 19454 | 5460 |
CTDSPL2,VIRMA,RHOH,TBC1D1,DDX39A,INSIG2,ELFN1,ATG16L1,TBC1D4,PDF,RHOG |
| 1.595e-02 | -4.14 | PDLIM4 (PDZ and LIM domain 4) | protein interactions | 8572 | 21 | 11 | 19454 | 5460 |
G3BP1,KRAS,HSPA8,NMRAL1,EWSR1,PML,FAM222B,HRAS,SDCBP,AMT,MYC |
| 1.595e-02 | -4.14 | AFP (alpha fetoprotein) | protein interactions | 174 | 21 | 11 | 19454 | 5460 |
PTEN,RAF1,EHD4,CREBBP,CCR5,STAMBP,GNB1,PSMB7,MED27,SPPL3,PHB2 |
| 1.595e-02 | -4.14 | SCARF2 (scavenger receptor class F member 2) | protein interactions | 91179 | 21 | 11 | 19454 | 5460 |
SFTPC,TRIM23,CHRNB2,SAR1B,LMBR1L,TP53,CUL3,NOTCH2,SEC61B,SPINT2,KLHL22 |
| 1.595e-02 | -4.14 | CDYL2 (chromodomain Y like 2) | protein interactions | 124359 | 21 | 11 | 19454 | 5460 |
PRMT5,LMO3,HINFP,MOV10,VIRMA,ESR2,HUWE1,HNRNPL,H3C1,ZSCAN5A,HSP90B1 |
| 1.595e-02 | -4.14 | DENND2B (DENN domain containing 2B) | protein interactions | 6764 | 21 | 11 | 19454 | 5460 |
SFN,HNRNPC,MYC,CSK,PPP1CB,YWHAH,YWHAG,YWHAZ,YWHAB,SMAD2,HNRNPL |
| 1.595e-02 | -4.14 | KLHL6 (kelch like family member 6) | protein interactions | 89857 | 21 | 11 | 19454 | 5460 |
CUL3,KLHL7,ZYX,ELF1,DHRS4,NUDCD3,CSNK2A1,RC3H2,PPP1R1B,HSP90AA1,TMPO |
| 1.595e-02 | -4.14 | AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) | protein interactions | 116986 | 21 | 11 | 19454 | 5460 |
GRIA2,CDK4,ARF1,AKT1,PIK3R1,RAC2,CDC42,NF2,BTG3,YWHAB,HOMER1 |
| 1.595e-02 | -4.14 | AMBP (alpha-1-microglobulin/bikunin precursor) | protein interactions | 259 | 21 | 11 | 19454 | 5460 |
RAF1,ENO1,DAAM1,F2,PIK3R3,ALB,FHL3,COX8A,CTSB,PIK3CA,USP15 |
| 1.595e-02 | -4.14 | CXCR1 (C-X-C motif chemokine receptor 1) | protein interactions | 3577 | 21 | 11 | 19454 | 5460 |
GNA14,FATE1,CXCL1,TUBA1A,CXCL8,ADRA1A,CXCL3,GNAI2,CXCR1,CLDND1,CDK1 |
| 1.595e-02 | -4.14 | KANK4 (KN motif and ankyrin repeat domains 4) | protein interactions | 163782 | 21 | 11 | 19454 | 5460 |
CSK,MYLIP,TRAPPC1,HOMER3,TRIM11,TRAPPC10,TRAPPC3,TRAPPC14,TRAPPC4,TRAPPC6A,VIRMA |
| 1.595e-02 | -4.14 | POLR2J3 (RNA polymerase II subunit J3) | protein interactions | 548644 | 21 | 11 | 19454 | 5460 |
RPAP2,TTC23,POLR2D,POLR2C,GPN2,ATPAF2,POLR2L,TSPYL4,DUSP3,HNRNPL,KRAS |
| 1.595e-02 | -4.14 | Tsc1 (TSC complex subunit 1) | protein interactions | 64930 | 21 | 11 | 19454 | 5460 |
PYGB,CCAR1,DYNC1I2,SGF29,JAK1,CCNF,MRPS9,SLU7,DNM2,PDF,ANO3 |
| 1.595e-02 | -4.14 | KIF3C (kinesin family member 3C) | protein interactions | 3797 | 21 | 11 | 19454 | 5460 |
SAV1,STK4,AKAP12,KIF3B,DISC1,KIF3C,DYRK2,TFIP11,UBE2M,VIRMA,CDC5L |
| 1.595e-02 | -4.14 | PLAGL1 (PLAG1 like zinc finger 1) | protein interactions | 5325 | 21 | 11 | 19454 | 5460 |
RPN1,TP53,SUMO1,CREBBP,OST4,PLAGL1,APEX1,PML,SMAD3,EP300,UBE2I |
| 1.600e-02 | -4.14 | EIF2B5 (eukaryotic translation initiation factor 2B subunit epsilon) | protein interactions | 8893 | 167 | 60 | 19454 | 5460 |
STAU1,FBXW7,PIP4P1,TACR3,ATP5MK,RPA3,CD40,EXOSC4,EIF2B3,RPA2,CSNK1A1,PIP4P2,DYRK2,ATG16L1,SEC62,DYRK1A,APEX1,EIF3K,FAM210A,S1PR4,LMBR1L,CCNF,SYT2,EIF2S2,GSK3A,CD226,RIT1,GPR17,CUL3,MYC,KRAS,STX11,TCOF1,STX8,EFNB1,DMAP1,SIGLECL1,CA14,STX12,COMTD1,CLEC2B,ASPM,EIF2B2,PRNP,VTI1B,RPS16,CHMP2A,ILVBL,MGME1,PCDH9,CAMSAP2,OSBPL8,SMDT1,FAM174A,GMPPB,GMPPA,EIF3D,DDRGK1,XPO1,CSNK2A1 |
| 1.602e-02 | -4.13 | TTC17 (tetratricopeptide repeat domain 17) | protein interactions | 55761 | 111 | 42 | 19454 | 5460 |
TMEM106B,GARRE1,TMEM87A,IGF1R,CLEC12B,GPIHBP1,HSPA5,FKBP8,CNOT6L,FKBP2,ST7,CBLN4,TMEM106A,DNAJC25,ACVR1,SFTPC,NCR3,CHRNB2,ELSPBP1,PTPN1,SEC61B,RMDN3,DNASE1L1,HNRNPL,DNAJB9,DNAJC1,OS9,SEC63,FIBIN,ESR2,EGLN3,SMURF1,CFC1,RAB5C,CNOT2,BMPR1B,GGH,PPP1CC,LRRTM1,BICD2,SDF2L1,LYZ |
| 1.602e-02 | -4.13 | FAM3C (FAM3 metabolism regulating signaling molecule C) | protein interactions | 10447 | 111 | 42 | 19454 | 5460 |
RAB5A,SNAP23,TMEM106B,TMX2,RPA3,GALNT2,FLOT1,CLEC12B,MRPL41,GLRA2,TOMM7,SEC62,TMEM106A,DDX39A,MPV17,B3GNT2,TOMM22,RELL2,RPA2,LMNA,RMDN3,SSMEM1,CYB5R3,ELOVL4,KCNA2,NUP35,TMEM248,VIRMA,TMEM45B,B3GALNT1,RNASEH1,RALA,MGST3,GOLPH3L,SCN3B,MICB,CREB3,FCGR1A,ST3GAL4,PDZK1IP1,STX1A,PDCD1 |
| 1.602e-02 | -4.13 | HYPK (huntingtin interacting protein K) | protein interactions | 25764 | 111 | 42 | 19454 | 5460 |
CSNK2B,MAP1LC3A,BOLL,NAA11,MYL12A,HSP90AB1,RPL7,CDH11,MLF2,NAA50,MDFI,LAMP2,HSPA14,MLF1,CALR,PGAM1,PTTG1,HSPB1,RIT1,NME2,BECN1,HSPA8,PMAIP1,SEPHS1,NEDD8,HNRNPF,KRAS,EEF1A1,MAP1LC3B,LBR,GABARAPL1,KRTAP8-1,GABARAPL2,THAP1,NAA15,NAA16,TP53,SP4,MFAP1,ARCN1,RPA2,DNAJC2 |
| 1.608e-02 | -4.13 | vesicle budding from membrane | biological process | GO:0006900 | 80 | 33 | 18204 | 5365 |
TRAPPC10,SNX3,CHMP5,GOLPH3L,DNM2,WASL,TRAPPC13,CUL3,PICALM,SNAP91,TRAPPC2L,TMED9,TRAPPC1,TRAPPC3,CHMP4C,S100A10,PREB,AP3S2,SAR1B,TRAPPC6B,CIDEB,TFG,SEC23A,KLHL12,ARFGAP3,VAPB,VPS4A,AP2M1,SEC13,TRAPPC4,RAB1A,TRAPPC6A,SURF4 |
| 1.609e-02 | -4.13 | TRDN (triadin) | protein interactions | 10345 | 60 | 25 | 19454 | 5460 |
SEC63,ANKH,VTI1B,RMDN3,AIFM1,PPIB,EMC4,ABCC5,RPS4X,PXMP2,EMC8,EMC1,MPV17L2,EMC2,EFNB1,LRP10,TMEM106B,STX8,STX12,EMC9,TMEM205,SOCS3,GOSR2,EMC10,BET1 |
| 1.609e-02 | -4.13 | TMEM38B (transmembrane protein 38B) | protein interactions | 55151 | 60 | 25 | 19454 | 5460 |
COPE,SEC61B,HSD17B11,COX4I1,PTPN1,KCNA2,OSBPL8,FAM241A,LAMP3,LAMP2,SLC5A6,LRRTM2,TACR3,DERL1,CYB5B,CRELD1,SSR1,RPN1,ABHD5,ST7,HINT3,OTULINL,SEC62,POLR1D,CCDC47 |
| 1.609e-02 | -4.13 | MLX (MAX dimerization protein MLX) | protein interactions | 6945 | 60 | 25 | 19454 | 5460 |
YWHAG,CSNK2A1,YWHAZ,FIS1,SNX5,YWHAB,CSNK2B,UBE2I,LDLR,SNX1,APEX1,DDIT4L,LNX2,SAP30BP,MTCH2,GABARAPL1,GABARAPL2,MXD1,CASK,EWSR1,AKAP1,DERL1,BACH1,TNNT2,FKBP8 |
| 1.609e-02 | -4.13 | DMXL2 (Dmx like 2) | protein interactions | 23312 | 60 | 25 | 19454 | 5460 |
AQP3,RAB4A,FAF2,HCST,NPY2R,ATP6V1G2,RP2,NPTN,ATP6V1G1,TACR3,GLUL,CXCR4,RAB5A,RAB3A,DNAJC7,RAB11A,ATG9A,NTAQ1,ROGDI,PRNP,SPCS1,VIRMA,EGLN3,CCNF,YBEY |
| 1.609e-02 | -4.13 | LMBRD2 (LMBR1 domain containing 2) | protein interactions | 92255 | 60 | 25 | 19454 | 5460 |
AP2M1,OPRL1,GNAI2,VIRMA,CCR6,P2RY10,GPR17,OPRM1,PDCD1,LAMTOR1,BSCL2,TACR1,CXCR4,TACR3,SLC6A8,GRPR,KLRD1,TMEM59,LPAR6,HCST,TP53,PLD3,CRELD1,AQP3,LAMP5 |
| 1.609e-02 | -4.13 | RLF (RLF zinc finger) | protein interactions | 6018 | 60 | 25 | 19454 | 5460 |
ALB,MACROH2A1,PHF21A,ZNF330,CBX5,VIRMA,KLF9,APEX1,FZR1,HNRNPL,ATG7,RIT2,MYC,RIT1,CLK1,TRIM11,COIL,SSRP1,PAX6,H3C1,KDM1A,KRAS,SOX2,KLF3,CBX3 |
| 1.609e-02 | -4.13 | CORO2A (coronin 2A) | protein interactions | 7464 | 60 | 25 | 19454 | 5460 |
MAEA,CORO6,BAP1,DDX39B,THRAP3,HDAC3,RANBP10,ATG16L1,CAPZA2,SMARCB1,UBE2I,RB1,SDHAF2,CORO1C,NR1H2,DAPK1,ERH,VIRMA,SH3BGRL,RSPH1,FERD3L,ARMC8,VMP1,YPEL5,SMAD2 |
| 1.609e-02 | -4.13 | TUFT1 (tuftelin 1) | protein interactions | 7286 | 60 | 25 | 19454 | 5460 |
BIRC2,ZYX,TFPT,OIP5,KDM1A,KRAS,LMO3,ING5,MAX,GIT2,TFIP11,CCR1,GOLGA5,DMAP1,PHF21A,TRIM27,CREB1,RPRD1A,HMG20A,NUF2,CYTH4,EXOC1,ATF1,LMO2,CCHCR1 |
| 1.609e-02 | -4.13 | M6PR (mannose-6-phosphate receptor, cation dependent) | protein interactions | 4074 | 60 | 25 | 19454 | 5460 |
MOV10,SYNJ2BP,RPL6,NTRK3,REN,RPL37A,CCNF,ACOX1,ENO1,NDUFB4,ACP2,CNPY3,JUN,TAFA1,TOMM22,CYB5B,SMCO4,RPA2,FGFR1,HSPA8,DUSP9,RPA3,RPS28,STX7,RIGI |
| 1.609e-02 | -4.13 | UBE2Z (ubiquitin conjugating enzyme E2 Z) | protein interactions | 65264 | 60 | 25 | 19454 | 5460 |
TRIM3,RABGGTB,SYVN1,RNF5,RNF41,LNX2,SMAD1,RNF103,TRIM27,TRIM46,PRNP,RNF144B,PLEKHF2,DHX15,CEP19,MDM2,BMPR1B,MOV10,BAG3,GORASP2,XPO1,SMAD4,WDR12,DNAJB6,RNF139 |
| 1.612e-02 | -4.13 | mixed | COSMIC cancer mutations | mixed | 145 | 54 | 16828 | 4835 |
HBP1,IDH2,GSTA4,KDM2A,MAP1B,HUWE1,EXOC1,PDE4B,TF,OR9I1,RPGRIP1L,SHISA2,HRAS,EWSR1,GNAQ,STK11,NF2,FAM161A,TP53,MFAP3L,MET,CAP2,CENPP,ADCY2,ITGA2,KRAS,BAP1,INTS12,PRCP,TBC1D24,CTNNB1,GNA11,RB1,DICER1,NPC1L1,PIK3CA,ELFN2,KCND2,MYT1L,SF3B1,PPP2R1A,OR2D3,KIT,PTEN,MOB3C,MYO1B,TERT,IKZF2,CBL,ECD,IDH1,EDC3,CBX5,SMAD4 |
| 1.613e-02 | -4.13 | Prostate cancer | KEGG pathways | hsa05215 | 87 | 40 | 7161 | 2463 |
PIK3CA,SOS2,BAD,AR,CDKN1B,IGF1,FGFR1,HSP90AA1,PIK3R3,HSP90B1,NFKB1,AKT3,CDKN1A,CREB3,KLK3,AKT2,GSTP1,NKX3-1,CTNNB1,MAP2K1,CCND1,RB1,RAF1,MDM2,ATF4,CREBBP,CREB3L4,IGF1R,IKBKB,EP300,HRAS,NFKBIA,AKT1,PIK3R2,TP53,CREB1,PTEN,KRAS,HSP90AB1,PIK3R1 |
| 1.613e-02 | -4.13 | Prostate cancer | KEGG pathways | ko05215 | 87 | 40 | 7161 | 2463 |
KLK3,AKT3,CDKN1A,CREB3,HSP90B1,NFKB1,CTNNB1,MAP2K1,AKT2,NKX3-1,GSTP1,IGF1,SOS2,BAD,CDKN1B,AR,PIK3CA,HSP90AA1,PIK3R3,FGFR1,PIK3R2,TP53,AKT1,PIK3R1,HSP90AB1,CREB1,KRAS,PTEN,IKBKB,IGF1R,CREBBP,MDM2,ATF4,CREB3L4,RAF1,CCND1,RB1,NFKBIA,HRAS,EP300 |
| 1.616e-02 | -4.13 | glycosphingolipid metabolic process | biological process | GO:0006687 | 63 | 27 | 18204 | 5365 |
FUT1,KIT,CERK,ST8SIA5,B4GALT3,LARGE1,ST3GAL5,GAL3ST1,B4GALT6,B3GALT4,ST3GAL2,B3GALNT1,ITGB8,B3GALT1,ST8SIA4,ST6GALNAC3,B4GALT4,GALC,HEXB,FA2H,NEU1,UGCG,ST3GAL1,HEXA,FUT9,BAX,B3GALT2 |
| 1.616e-02 | -4.13 | regulation of receptor internalization | biological process | GO:0002090 | 63 | 27 | 18204 | 5365 |
LPAR1,ATAD1,LRRTM1,SDCBP,PCSK9,CD63,ARF1,VEGFA,GH1,HPCA,AP2M1,RALA,LRRTM2,MTMR2,SYK,OPHN1,APLN,TBC1D5,ANGPT1,MKLN1,DKK1,PICK1,GREM1,SFRP4,DLG4,VAC14,FLOT1 |
| 1.617e-02 | -4.12 | ITSN2 (intersectin 2) | protein interactions | 50618 | 142 | 52 | 19454 | 5460 |
LUC7L3,NOL7,FGFR1,FBXL19,ATG16L1,CHIC2,RNF41,LSM8,YTHDF1,RBM22,KDM1A,PTN,NUP50,NCKIPSD,MYO6,PCCB,PPP1CC,BTF3,TM9SF4,EPS8,SNRPB2,ESR2,VIRMA,BCCIP,FCHSD2,ROCK1,SNRNP40,TAB1,GPNMB,AP2M1,AP2S1,SGIP1,CCR1,EZH2,TNRC6C,SNAP29,SRFBP1,FASLG,RNF20,PSEN1,WASL,HNRNPK,SOS2,PIK3AP1,CBL,PSMD7,PPIL4,MRPL9,KXD1,ATG9A,KCTD10,DNM2 |
| 1.617e-02 | -4.12 | ANAPC1 (anaphase promoting complex subunit 1) | protein interactions | 64682 | 142 | 52 | 19454 | 5460 |
PPM1M,ANAPC2,PHF21A,CCNF,UBE2S,MAD2L1,CDC20,ESR2,VIRMA,DYRK1A,ANAPC15,DEPDC1B,CDC16,CUL3,CCNB1,PTTG1,ANAPC4,RIT1,ANAPC16,SIRT7,WBP2,SKP1,KDM1A,STAU1,CRYL1,NEK2,TPT1,ACACA,COPS2,HRAS,SRP14,EEF1AKMT3,EGLN3,CEP19,CDC5L,FZR1,SUMO2,MOV10,UBXN6,CDC26,CDC23,USP15,BRD3,H2AC4,RPAP3,MDC1,PAK6,H3C1,KRAS,SOX2,ANAPC13,GRAP2 |
| 1.619e-02 | -4.12 | secretory granule membrane | cellular component | GO:0030667 | 317 | 110 | 19108 | 5553 |
RAP1A,CPNE1,SELL,ATP8A1,RAP1B,CD14,LAMP3,STBD1,CAV2,RAB3A,FCER1G,ICA1,SNAP25,SNAP23,RAB18,PGRMC1,RAB5C,SYT2,ATP6AP2,SERPINA5,CD36,SVIP,SERPINB10,LAMTOR2,VAMP2,ANXA4,CD63,CLCA1,VAMP7,TYROBP,HMOX2,TMEM190,RAB31,TICAM2,PRCP,TMEM95,FABP5,TBC1D10C,CMTM6,BRI3,SIGLEC5,CYB561,ITGAV,CXCR1,SYNGR1,NDUFC2,IZUMO1,TOM1,LAMTOR1,TLR2,TMEM30A,GLIPR1,OLR1,DBH,RAB37,CYB5R1,CD46,FCGR2A,DNAJC5,B4GALT1,CYSTM1,NCSTN,SLC18B1,CD58,DYNLL1,TNFRSF1B,CD47,SURF4,RAB6A,ATP6V1D,RAB3D,FCAR,RHOG,TMX3,AP1M1,EXOC3,RAP2B,ANXA7,RAB9B,DEGS1,MME,TMBIM1,STOM,SRI,SLC2A3,LHFPL2,CAV1,VAMP8,MOXD1,VAMP1,SERPINB6,ENPP4,SLC30A5,SNAP29,LAMP2,LILRA3,RAP2C,LAMTOR3,CPE,SCG3,LGALS3,RAB14,BST2,CD59,TMEM179B,PSEN1,ORMDL3,RND2,SYT4,CD9 |
| 1.619e-02 | -4.12 | NUMBL (NUMB like endocytic adaptor protein) | protein interactions | 9253 | 108 | 41 | 19454 | 5460 |
RAB4A,SPSB3,FGFR1,TAB2,KBTBD4,TULP3,KRAS,STX7,FLOT1,DVL2,PML,BHLHE40,UBE3A,RAB9A,PSMA3,IGF1R,LAMTOR1,TRAF6,YWHAZ,YWHAB,LAMP2,RAB11A,LAMP3,YWHAH,YWHAG,XPO1,DNAJC5,DDRGK1,HNRNPL,ARF6,SIAH1,ACTB,RHOJ,DIRAS3,STX6,CAV1,HRAS,RAB35,SMAP2,GJA1,SLC1A1 |
| 1.619e-02 | -4.12 | REPIN1 (replication initiator 1) | protein interactions | 29803 | 108 | 41 | 19454 | 5460 |
PHB1,KRR1,SRP14,PRKRA,RPL35,RPL13A,RPL7L1,RPS27L,SURF6,RPL7A,NOP16,HNRNPC,BAZ1B,GMNN,RBM15B,NONO,TRIM23,CDC23,RPS2,PPAN,RPA3,NEK9,RPL27,RNF113A,RPL3,KCTD17,FBXW7,NOP53,HDAC3,DGCR8,PPP2R2C,MRPS7,POLA2,MATN4,NOTCH2,IPO8,TOP3B,RAF1,AURKAIP1,HGS,RPLP0 |
| 1.624e-02 | -4.12 | SP1 (Sp1 transcription factor) | protein interactions | 6667 | 354 | 118 | 19454 | 5460 |
CTNNB1,PFDN5,HMGA1,IFI16,HSPB1,FKBP4,DROSHA,MAP1LC3A,NKX3-1,SIN3A,SP2,TMEM237,SUMO2,PGR,RPS10,ELF1,ERLIN2,SAP30,JUN,TUBA1A,VDR,RBPJ,BAG2,MYO1B,MEF2C,AP1M1,DMPK,RBBP7,ZBTB16,LDB1,CUL3,LMO2,CREBBP,MYC,NFYA,HSP90AA1,ICAM1,SP1,BRCA1,MYO6,VEGFA,ESR2,DES,RBBP4,RPL35,CDKN1A,NOTCH2,SYK,NUP62,GTF2IRD1,PPARG,ABCB1,CTBP1,USP39,EP300,DDX5,HSPA8,DNAJC3,TNFSF10,ZBTB5,MSX1,IL1B,TPM3,CSNK2A1,NFKB1,SHC1,SMAD4,RB1,SMAD3,SSBP1,KLF9,CD2,ZBTB2,MDM2,MYL12A,ST3GAL5,TP53,RPSA,CDK4,SP4,CD209,HINT1,KLF10,MNAT1,EGR1,AR,ARHGAP21,CCNB1,SUB1,FGFR1OP2,AKT1,PPIG,CALU,SMAD2,NR2E1,MECP2,PSMC5,GTF2A1,TUBA1B,GABPA,CCNA2,CCND1,NFYB,SF3A1,ATG16L1,KLF4,CDK1,TWNK,PML,BANF1,BAP1,BCL6,AATF,HSPA5,COL3A1,NF2,HDAC3,RPS15 |
| 1.626e-02 | -4.12 | Apoptosis | WikiPathways | WP254 | 86 | 41 | 5310 | 1910 |
BOK,IGF1R,CRADD,JUN,BAD,TNFSF10,NFKBIA,BIRC5,IRF2,IRF6,CASP4,IRF4,FAS,NFKB1,TRAF1,NFKBIB,TNF,BAX,BNIP3L,TRAF2,IRF1,DFFA,IGF1,BCL2L1,LTA,IRF7,HELLS,MCL1,TP53,AKT1,MAPK10,IKBKB,MYC,BIRC2,PIK3R1,PMAIP1,MDM2,BAK1,FASLG,TNFRSF1B,IRF3 |
| 1.626e-02 | -4.12 | organelle organization | biological process | GO:0006996 | 3091 | 961 | 18204 | 5365 |
MCMBP,WDR83OS,NEFL,PRKCA,LMAN1,MTRES1,LDB1,EIF4E2,TRAPPC10,H1-6,GAS2,EXOC8,RIMOC1,INA,EXOC5,HSD17B1,RHOH,TMEM126A,ACOT8,DES,RPS28,UFM1,RPF2,PEX3,INPPL1,DNAL1,VAMP2,USP16,CIDEB,ATG3,PPAN,RFC4,HSP90B1,PLEKHJ1,FBXW11,CTTN,PITPNB,CORO1C,YTHDF1,HMGB1,MAPRE2,PTK7,STX1A,NTNG2,H2BC1,INO80C,EMC6,VPS28,S100A10,PREB,TRIM46,BCCIP,KATNAL1,RHOB,PLEKHF1,STXBP6,BRIX1,PLAAT3,ATPAF2,DDRGK1,ROCK2,STN1,RAF1,ARMCX3,RAB2A,MIR145,RFC5,TAGLN3,TMEM106B,RAB11A,RPS3,ATL1,CNTNAP1,H1-1,RAB6B,VAMP7,F11R,TMOD1,RAP2A,GABARAPL2,TMED5,LYRM2,RHOJ,TMEM237,CETN3,SESN2,STX12,RACGAP1,LIPA,TPM3,YIPF4,CSNK1A1,FUNDC2,CLN8,TRAK2,RAD21,MKKS,FANCG,CNOT7,CHCHD4,GAPDH,IKBKB,MREG,RPS5,COA1,CEP41,CAPG,YTHDF2,ADCK1,EZH2,RAB32,EZH1,TBCE,RAC2,NDUFAB1,RRP7A,CHMP1B,HUWE1,DCLRE1C,POLR1B,TOMM70,CCL11,TRIM27,TFPT,DNAAF10,GHITM,SKA2,BLOC1S2,BCS1L,ERCC3,COX10,ATG101,VPS4A,RANBP10,ARHGAP21,CFAP298,CIRBP,ARHGAP25,CTNNA2,SPECC1L,FEN1,PRM1,PTTG1,SLC35F6,CHCHD3,NDUFA2,PICALM,MAD2L1,HPS6,TTC8,NCKAP1,PLS3,CAV2,TMOD2,KLHL1,ACTN4,RETREG3,PRKCB,CHGA,SHC1,MAP1LC3A,SETD3,SUMO1,CLRN1,WASL,TRIM37,GCLC,NDUFA1,PEX13,ATP6V1G1,EIF2D,TPPP,SNX33,TIMM10,VPS4B,WASF3,FUNDC1,PROX1,SMC4,KLHL12,STBD1,SRPK2,KRAS,REEP3,PAK6,CHP1,PCNA,SEC22B,TWNK,FGF10,EMC2,NCK1,FBXL4,TF,SHOC1,ZMPSTE24,CLVS2,ALKBH5,BRCA1,TRAM2,SNX3,IFT57,UBE2I,PSEN1,MTM1,RPS27L,ATG9A,ATP6V1A,MCOLN1,CAV1,CFAP161,USP8,ARPC2,TNKS,AGAP2,TMEM70,HSP90AB1,RAB1A,PIM2,ZYX,BLOC1S3,PLEKHF2,CAV3,LCA5L,CNTROB,MSRB1,TRAPPC13,PSRC1,TRIM36,CDK1,SSBP1,ATP6AP2,INPP5K,HSP90AA1,NDUFA12,SNAP25,PWP2,ZMYM3,CDK5R1,NAA50,MTCH2,WDR45,UQCC6,G3BP1,ATP6V0B,ZNF207,FITM2,PHF13,IER3,TMSB10,TUBA1B,CREB1,MYC,SELENOF,RPL23A,TOMM40,TDRD7,PRDX3,GOSR1,ZFAND6,FAF2,CDC20,PLN,CD2AP,LAMTOR1,NEK2,NDP,TSPO2,MARCKSL1,TRAF6,GADD45A,NLGN2,VPS16,ESYT1,SYCE3,ARMC1,RAB19,HCLS1,PSPC1,DISC1,TASL,CFAP97D1,PML,SSNA1,TERT,NDUFB5,RPL24,EIF2S1,TESK1,FGF13,MRAS,UBXN2B,CLU,COX19,UBL4A,NDUFA5,CCDC32,ATG16L1,IFIT2,ATG4A,KCNJ10,EIF1AX,RILPL2,TMEM108,TEX19,TEX264,CLTRN,CORO6,LYSET,RND3,MKLN1,TFIP11,AP3S2,TOMM7,PET117,ZMYM6,NBN,ACTR2,TMED3,BLOC1S5,SNX11,FBXO7,MPV17L2,COX17,EMC9,EFHC1,MAIP1,NDC80,TFE3,TOMM6,TRAPPC4,TMEM199,EDC3,BNIP3L,MIR29A,SRGN,EXT1,PTGES3,SMARCA5,PPID,C1QL3,DAG1,SLC25A46,SRC,PHB2,SQSTM1,EPS8,TRIM21,MCM3,MEIOB,SEC23A,STX5,DYNLL1,CAMSAP2,BIRC5,SNX10,MEF2A,TMCC1,RAB8B,TESK2,USP30,CHAMP1,GOLGA5,TOM1,ENKD1,TMEM126B,CDC42EP2,TIMM8A,ATP5IF1,TOR1AIP2,NUP153,SS18,MSN,ATG4C,CRKL,RRN3,JAK2,MCPH1,PTEN,STXBP1,BCL2L1,MIS12,STX7,GSK3A,RAB27A,TUBA1A,ABCE1,CD34,SMCHD1,SSX2IP,FGD2,BAD,PEX26,AIF1L,LMNA,STARD13,ASZ1,PHETA2,NOP53,LSM4,GABARAP,PRMT5,SDHAF2,PDLIM3,INO80E,RSPH1,VDAC2,PDCD10,UQCC3,RFC3,TTL,AP1M1,RPSA,BOK,HSD17B10,VAMP1,PACSIN3,CATIP,NPR2,CTSK,SHLD1,CTNNB1,IFT25,CCL24,RTN4,EMP2,SMURF1,B9D2,SEPTIN6,FMC1,DNM2,NOS1AP,UBE2B,MFN1,TIA1,MAEA,MYBL2,POC1B,KLHL24,CKS2,COX7A1,TRAPPC1,NOA1,RPS23,CHMP2A,TIMM29,BCL2A1,TRAPPC6B,MLH3,AQP2,SNAPIN,PMAIP1,RMI2,ARPC3,H3C1,NDUFS3,RPLP0,CHCHD6,VPS33A,NCKIPSD,TOP3B,ROPN1B,USP6NL,HSPD1,AP1S2,MRPS7,TRAF7,MAP4,PAK5,SNAP91,STOML2,KCNF1,MYO6,RNF14,LRRC4,KBTBD13,NDUFB6,UBB,CAMLG,RTKN,CFL2,COA4,MIR17,RP2,SEC61A1,GJA1,TPPP3,AIF1,H1-5,RETREG2,ARF6,CLDN3,CTSD,LSM3,LSM14A,TOP1,TOMM20,TMSB4X,TRAPPC6A,TAFAZZIN,RAB31,RPL6,TMEM107,RB1,NUP35,SDHAF1,SLC25A5,WDR44,TNFAIP1,ZNF365,RANGRF,TOP2B,FGF7,TOPBP1,NSFL1C,ELMO1,PHACTR1,CDK5,GOLPH3L,BCL6,RHOU,CNN3,PCLAF,FITM1,ARHGAP12,MYO1B,VAPB,TNF,HAUS2,CLVS1,HMGA1,ACTB,NDUFAF2,MUL1,PPT1,CAPZA1,GINS4,NGRN,TRAPPC14,SEC13,SLC25A4,TEX12,SLAIN2,PHB1,CSRP1,RPA2,OIP5,RUVBL1,KLHL22,APOO,RHOG,COA5,CHMP5,FOXJ3,SUV39H1,PPP2R1A,MAPRE1,CHMP4C,DSTN,RETREG1,UFL1,SLC16A1,BET1,SGTA,DAAM1,CAP2,SAMM50,CEP70,SDHAF4,CCSAP,PIWIL1,GABARAPL1,CFAP91,HEXB,ATAT1,TMEM38B,TRIP4,EMG1,RAB30,TMEM33,CHORDC1,TRAM1,HSPA8,LARGE1,PTPN1,TMEM147,TOR1B,TMED7,SPTSSB,ZBED3,TMEM14A,RPS15,IFI6,DLG4,ARF4,TMEM165,SDCBP,ACTL6B,TP53,MAP1S,MAEL,VCPIP1,SKA1,TUBG1,KIF3B,MCM4,CNP,EHD1,ASCC1,NEK7,SOD2,GHRL,VTA1,SOX9,BAG3,FIS1,BECN1,TRAPPC3,SPATA6,UBXN10,DLG1,RAB3A,EMC1,BANF1,RAB13,MIR29C,NHP2,PELO,TAGLN2,CYTH2,ACTL9,HGS,CFAP61,WDR11,VIPAS39,SKA3,RABL2B,TOMM22,GAS8,ATP6V1C1,RFC2,RMI1,RFLNA,VAMP8,RPA3,RAB1B,H2BW1,DHX9,RNF8,GINS3,ELMO2,DDX4,MCM8,CXCL1,CFAP20,C9orf72,REEP6,ZNF501,LCA5,GTF2B,RAB29,ADD1,LORICRIN,JAGN1,EMC4,LTO1,NTMT1,OPHN1,HTRA2,IFT22,TMEM127,NDUFC2,RPL10L,FXN,ATP2C1,TYROBP,TMEM11,THG1L,SSH3,SWAP70,H1-10,ING2,AP2M1,RUVBL2,SEPTIN7,COG1,GPR35,VTI1B,RAB18,CCL3,NDUFS8,MAP1LC3B,FHL3,UNC119B,NDUFB7,ATP6V1D,STX8,RFX4,CFL1,PARD6A,RNASEK,C1QL2,SPEF1,ZDHHC15,ADD2,RPS14,GGCT,RCHY1,GOSR2,IFT172,CRYAB,LIMD2,CDC42,PPIA,STX6,DMPK,SNAP23,TBCEL,CENPP,TACO1,VAMP3,AKAP8L,VPS54,TRMT10B,FAM161A,YIPF5,FEZ1,PPIF,NPTX1,RNF26,XRCC5,CHCHD2,SYP,CCL2,CLXN,NPPC,NHERF1,DCTN6,TRAM1L1,TUBB,EIF5B,ARL6,EHD3,NUP62,LRRC61,ATP5F1D,CCDC42,TIMM8B,TMEM231,GK2,RAB14,ARFGEF1,NUF2,HDAC6,FBXW7,POLDIP2,STX16,CCAR2,STX11,TMED9,ALKBH4,UBAP1,NAIF1,SPTBN1,WEE2,VMP1,TMOD3,TRIM32,RAB33B,TIMM13,MRM2,RHOBTB1,RAB33A,AGK,CUL3,MTX2,WDR19,CCDC47,RAN,YWHAZ,BSCL2,TERB2,STX17,COX16,NDUFAF4,STMN2,TIMM21,BICD2,NDUFB8,CCNB1,GORASP2,NDUFB4,HIGD2A,TMEM170A,EMC8,RRM1,VRK1,CAPZA2,NF2,PPM1K,CEP85,NDUFAF6,NDUFB10,RB1CC1,NDE1,H1-3,WRAP53,UQCC2,HIKESHI,FASLG,PARP11,COX14,NECTIN2,HNRNPA2B1,TRAPPC2L,TFEB,STX18,THY1,PIK3CA,ARFGAP3,NLE1,PAFAH1B1,IFT52,TCAP,NLGN1,APEX1,FIG4,TNNT2,NUP107,RAB22A,COX20,BMERB1,CDC23,SPTAN1,NDUFS2,NDUFAF3,SURF4,ROCK1,STX10,GFM2,CENPW,MIR143,MND1,TERC,FHIP1B,KIT,PID1,TUBB4B,MSH6,HIGD1C,REEP4,KIF2A,SOD1,RND2,AR,TSG101,PIP5K1A,TFG,RPGRIP1L,PLA2G5,CCDC69,KRT7,LCP1,PARL,KRT8,ACP2,ITGB5,FAM107A,AIFM1,AKT1,TMED4,CFAP73,SLC25A31,VPS39,B9D1,UCP2,CIBAR1,DKC1,ROMO1,CALR,SIRT7,ATP6V1G2,SKIC8,PYROXD2,MAP1B,BAK1,TNFAIP3,NUDCD3,HDAC3,ATG7,RPL10,MCL1,CATSPERZ,FHOD3,EHD4,SELENON,AQP11,DNAJB6,SYT4,SFN,OCRL,DTD1,LPCAT3,UBE2S,TNIK,PAX6,MAD2L2,TPPP2,CCDC65,CCSER2,EDNRA,PEX5L,SIPA1L1,SAR1B,MGME1,CHMP2B,OPTN,VPS18,GABPB1,NCAPG2,TP53INP2,MNS1,SCLT1,PDLIM4,ATXN10,ACTL6A,PPP2CB,PPP1R12A,TMED1,AKT3,MPV17,CLIP3,E2F4,LMNB1,IQSEC1,SNAP29,SPRY1,HAX1,FAM149B1,TENT4A,SLX1A,EMC10,BBS5,G3BP2,MACIR,RAB23,IMMP2L,DDX1,MCM6,KLHDC8B,LAMP2,TP53INP1,BAX,HEXA,MIEF1,CHMP1A,ZMYM4,ACAA2,ASPM,CETN2,CEP19 |
| 1.627e-02 | -4.12 | positive regulation of endoplasmic reticulum unfolded protein response | biological process | GO:1900103 | 13 | 8 | 18204 | 5365 |
BOK,PTPN1,BAK1,AGR2,TMEM33,PIK3R1,XBP1,BAX |
| 1.627e-02 | -4.12 | negative regulation of cell growth involved in cardiac muscle cell development | biological process | GO:0061052 | 13 | 8 | 18204 | 5365 |
PI16,CAV3,RGS2,G6PD,PPARA,GSK3A,FOXP1,TOMM70 |
| 1.627e-02 | -4.12 | regulation of retrograde protein transport, ER to cytosol | biological process | GO:1904152 | 13 | 8 | 18204 | 5365 |
UBE2G2,OS9,EDEM2,UBAC2,ERLEC1,EDEM1,DERL2,SVIP |
| 1.627e-02 | -4.12 | cytidine deamination | biological process | GO:0009972 | 13 | 8 | 18204 | 5365 |
APOBEC3F,APOBEC3A,APOBEC3C,APOBEC3D,APOBEC3H,DCTD,APOBEC3B,APOBEC3G |
| 1.627e-02 | -4.12 | negative regulation of autophagosome assembly | biological process | GO:1902902 | 13 | 8 | 18204 | 5365 |
FEZ1,MTM1,NUPR1,TMEM39A,SCFD1,PHF23,SEC22B,BECN1 |
| 1.627e-02 | -4.12 | type II interferon-mediated signaling pathway | biological process | GO:0060333 | 13 | 8 | 18204 | 5365 |
IFNG,TP53,JAK1,STAT1,IRF1,RAF1,IFNGR1,JAK2 |
| 1.627e-02 | -4.12 | negative regulation of monooxygenase activity | biological process | GO:0032769 | 13 | 8 | 18204 | 5365 |
CAV3,MIR378A,CYP27B1,NFKB1,GFI1,ATP2B4,NOSIP,MIR130B |
| 1.627e-02 | -4.12 | positive regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045737 | 13 | 8 | 18204 | 5365 |
PSRC1,CCND1,CCNY,PSMD10,RGCC,CCND3,PROX1,AKT1 |
| 1.627e-02 | -4.12 | myoblast proliferation | biological process | GO:0051450 | 13 | 8 | 18204 | 5365 |
FGFBP1,FGR,SRC,GPX1,CTNNB1,IGF1,FGF7,FOS |
| 1.627e-02 | -4.12 | regulation of T-helper 2 cell cytokine production | biological process | GO:2000551 | 13 | 8 | 18204 | 5365 |
IL6,IFNB1,RSAD2,IFNA2,NLRP3,IL4,XCL1,CD81 |
| 1.627e-02 | -4.12 | positive regulation of inflammatory response to antigenic stimulus | biological process | GO:0002863 | 13 | 8 | 18204 | 5365 |
FCGR1A,CNR1,KARS1,CD81,LTA,CD28,CCR7,TNF |
| 1.627e-02 | -4.12 | viral budding from plasma membrane | biological process | GO:0046761 | 13 | 8 | 18204 | 5365 |
CHMP1B,VPS4A,CHMP5,CHMP1A,VPS4B,CHMP2A,CHMP4C,CHMP2B |
| 1.627e-02 | -4.12 | cytidine metabolic process | biological process | GO:0046087 | 13 | 8 | 18204 | 5365 |
APOBEC3D,APOBEC3A,APOBEC3F,APOBEC3B,APOBEC3G,APOBEC3H,DCTD,APOBEC3C |
| 1.627e-02 | -4.12 | cytidine catabolic process | biological process | GO:0006216 | 13 | 8 | 18204 | 5365 |
APOBEC3H,DCTD,APOBEC3G,APOBEC3B,APOBEC3C,APOBEC3D,APOBEC3F,APOBEC3A |
| 1.627e-02 | -4.12 | positive regulation of toll-like receptor 4 signaling pathway | biological process | GO:0034145 | 13 | 8 | 18204 | 5365 |
PELI1,CD14,NINJ1,TICAM2,TIRAP,ZNRF1,IFI35,PTPN22 |
| 1.627e-02 | -4.12 | response to parathyroid hormone | biological process | GO:0071107 | 13 | 8 | 18204 | 5365 |
MEF2C,FGF23,ITGA2,CITED1,WNT10B,FOS,SOST,HDAC6 |
| 1.627e-02 | -4.12 | primary miRNA processing | biological process | GO:0031053 | 13 | 8 | 18204 | 5365 |
SMAD1,DROSHA,DGCR8,SMAD2,DDX5,SMAD3,NCBP2,HNRNPA2B1 |
| 1.629e-02 | -4.12 | FOXR2 (forkhead box R2) | protein interactions | 139628 | 40 | 18 | 19454 | 5460 |
TADA1,POMP,DMAP1,PSMG2,SUV39H1,MORF4L1,TXNRD2,ARHGAP1,MAX,MYC,TAF5L,DYRK1A,RUVBL1,MEAF6,PSMA5,RUVBL2,RCBTB1,VPS72 |
| 1.629e-02 | -4.12 | MPP2 (MAGUK p55 scaffold protein 2) | protein interactions | 4355 | 40 | 18 | 19454 | 5460 |
MTPN,LIN7B,ARMC8,ZER1,SLC20A1,PALS2,METTL14,NGB,CSNK2B,GID4,LIN7C,DLG1,PTGES3,CDC5L,SRC,NF2,HSCB,PRNP |
| 1.629e-02 | -4.12 | NR1I3 (nuclear receptor subfamily 1 group I member 3) | protein interactions | 9970 | 40 | 18 | 19454 | 5460 |
SRC,UBB,SNRPD3,PRNP,MED17,TRIM24,PSMC5,HSPA8,PML,MAP4,POU1F1,MED4,HSP90AA1,PPM1B,NR0B1,MED23,FTH1,PSMC4 |
| 1.629e-02 | -4.12 | SYT16 (synaptotagmin 16) | protein interactions | 83851 | 40 | 18 | 19454 | 5460 |
TVP23B,RER1,ZBTB14,HIGD1C,PLEKHF2,CYSTM1,APOC4,RPRM,RTN4,SEMG2,RABAC1,REEP6,NCOA5,SDR16C5,APOC2,AGTRAP,DUSP14,H1-5 |
| 1.629e-02 | -4.12 | CAAP1 (caspase activity and apoptosis inhibitor 1) | protein interactions | 79886 | 40 | 18 | 19454 | 5460 |
SNRPA,DDX39B,DLST,KLHL28,RTCB,PTN,STAU1,THOC1,AKAP17A,ESR2,ATG16L1,RAF1,ING5,DDRGK1,SNRPB,DDX23,SNRNP70,BRD3 |
| 1.629e-02 | -4.12 | Itgb1 (integrin beta 1 (fibronectin receptor beta)) | protein interactions | 16412 | 40 | 18 | 19454 | 5460 |
PDIA3,SLC25A1,RPRD1B,ATP5PO,TIMM23,DDX42,UBAC2,HSP90B1,ITGA6,SLC25A5,ATP5MK,FZD6,ITGA2,SRPRB,RBCK1,SSR3,ITGAV,GALNT2 |
| 1.629e-02 | -4.12 | KYAT3 (kynurenine aminotransferase 3) | protein interactions | 56267 | 40 | 18 | 19454 | 5460 |
RABIF,HNRNPL,ATP6V1G2,OXCT1,IDH1,AGA,TES,RPA3,ENO2,LMNA,RPA2,CHCHD4,RNF7,COPS5,PGM1,MOV10,CSK,TXNRD2 |
| 1.629e-02 | -4.12 | CALHM4 (calcium homeostasis modulator family member 4) | protein interactions | 221301 | 40 | 18 | 19454 | 5460 |
KDELR2,DUSP14,PTDSS1,LACC1,SGIP1,CSGALNACT1,PNMA2,CAPZA2,OAZ3,RAB9B,SEMG2,OR51E2,FBXO3,FOS,FBXL4,RAB11B,CPLX3,SPPL3 |
| 1.629e-02 | -4.12 | COG8 (component of oligomeric golgi complex 8) | protein interactions | 84342 | 40 | 18 | 19454 | 5460 |
P2RY10,COMTD1,OPRM1,GPR17,COMMD8,HGS,CA14,SIGLECL1,ATP6V1A,RAB1A,CD274,CD40,LMBR1L,MYEF2,VIRMA,COG1,NPTN,RP2 |
| 1.630e-02 | -4.12 | L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2) | protein interactions | 83746 | 202 | 71 | 19454 | 5460 |
PFDN5,ZMYND11,GAS8,SUV39H1,XPO1,LHX2,DNAJC7,RB1,TCP1,ATXN10,MEAF6,CCT7,CCT5,MAX,THAP1,ELF1,SPRR1B,VPS33A,CBX3,TNNI1,CHAMP1,PHC1,PSMC3,MTA2,POLR2C,RBPJ,ZBTB26,CCT8,RING1,PICK1,DNAJB4,MRFAP1,H3C1,PCGF3,PCGF6,RERE,STAC3,MYC,DNAJC5,GPRASP3,KANSL3,IRF1,TADA3,CCT2,TFDP2,PFDN2,ELK3,PHF21A,ZMYM2,TAX1BP1,LRIF1,MAD2L1,CCND1,LNX2,KLF12,GKAP1,ADNP,KLF3,MXD1,E2F6,BAP1,PCGF2,YAF2,CCDC106,ZFP64,HSPB2,HDAC3,FTL,PIAS1,TRIM52,MBD3 |
| 1.632e-02 | -4.12 | SCYL1 (SCY1 like pseudokinase 1) | protein interactions | 57410 | 164 | 59 | 19454 | 5460 |
MAPKAPK3,SLU7,RPA3,EP300,P4HA2,SF3B1,SYVN1,MBD3,POLA2,COIL,SEC22B,NEK7,CDC42,RND2,OTULINL,USE1,ARCN1,METAP2,LMBR1L,ARF1,CCNF,CLXN,ACTB,COPE,DAPK1,ESR2,SMURF1,SEC13,MYC,PSMD1,SMARCE1,SMPD2,TCEA2,LSM14A,SRSF7,ACTR1B,THRAP3,SATB1,EIF3E,SAR1B,RIGI,MAP1LC3B,EZH2,KLHL12,SMARCB1,SRSF1,CTDSPL2,TES,GJA1,PLEKHF2,CHMP2A,SLC25A46,EIF3D,XPO1,SLC35A1,DDX23,DICER1,VPS4A,DDX1 |
| 1.635e-02 | -4.11 | negative regulation of osteoclast differentiation | biological process | GO:0045671 | 33 | 16 | 18204 | 5365 |
IL4,LILRB1,TLR3,TCTA,CCL3,PIK3R1,TLR4,UBASH3B,LILRB4,CARTPT,GPR137,SFRP1,CTNNB1,TNFAIP6,FBXW7,TOB2 |
| 1.635e-02 | -4.11 | response to prostaglandin | biological process | GO:0034694 | 33 | 16 | 18204 | 5365 |
PTGER4,ACACA,PTGER2,SFRP1,AANAT,CCR7,CCL19,PRKCE,AKT1,PTGFR,GNG2,AKR1C2,P2RY4,GNB1,PAX6,CCL21 |
| 1.637e-02 | -4.11 | CD5 (CD5 molecule) | protein interactions | 921 | 29 | 14 | 19454 | 5460 |
DYNLT3,IDE,CD2,PRKCB,CD4,CD79B,ARL10,PRKCA,CD247,CBL,ZER1,CSNK2A1,PIK3R1,SPR |
| 1.637e-02 | -4.11 | TVP23B (trans-golgi network vesicle protein 23 homolog B) | protein interactions | 51030 | 29 | 14 | 19454 | 5460 |
CEP19,TLCD4,RIGI,REEP4,HSD17B11,PRKCB,TMX2,TMEM14B,TMEM31,YIPF4,DDX39A,SCN3B,ABHD6,TIMMDC1 |
| 1.637e-02 | -4.11 | ITPK1 (inositol-tetrakisphosphate 1-kinase) | protein interactions | 3705 | 29 | 14 | 19454 | 5460 |
SCN2B,NFKBIA,LIPA,HNRNPL,PRNP,CDC5L,MOV10,TP53,CUL3,HMGCS1,TRAF2,JUN,P2RY10,UBE2H |
| 1.637e-02 | -4.11 | RAB39A (RAB39A, member RAS oncogene family) | protein interactions | 54734 | 29 | 14 | 19454 | 5460 |
RAB14,EGLN3,RDH10,LMBR1L,CCNF,RPA3,RPA2,NTRK3,HEXIM1,FURIN,C9orf72,UBL4A,SOX2,GORASP2 |
| 1.637e-02 | -4.11 | NAA30 (N-alpha-acetyltransferase 30, NatC catalytic subunit) | protein interactions | 122830 | 29 | 14 | 19454 | 5460 |
ATP1A3,ISYNA1,PTAR1,NAA35,NKIRAS1,BTF3,TUBA1A,CD2BP2,STAU1,DUSP19,ACTA2,RTKN,RLIM,HAPSTR1 |
| 1.637e-02 | -4.11 | LUM (lumican) | protein interactions | 4060 | 29 | 14 | 19454 | 5460 |
CTSB,TRA2B,THUMPD1,RSRC1,EXOSC4,MMP14,GNAQ,COL1A2,PTPN11,RAF1,CFTR,LRRC40,UBLCP1,SOX2 |
| 1.637e-02 | -4.11 | STARD9 (StAR related lipid transfer domain containing 9) | protein interactions | 57519 | 29 | 14 | 19454 | 5460 |
RPA3,HNRNPA2B1,MCL1,ABCE1,VIRMA,CSK,RAF1,YWHAG,YWHAH,PPP1CC,RPA2,YWHAZ,CHMP4C,YWHAB |
| 1.637e-02 | -4.11 | OXR1 (oxidation resistance 1) | protein interactions | 55074 | 29 | 14 | 19454 | 5460 |
RAB11A,ATG9A,GTF2E1,RPL24,RAB4A,LAMTOR1,RAB9A,RPS20,RAB3B,TOLLIP,RBIS,KRAS,NMI,STX7 |
| 1.637e-02 | -4.11 | ALG6 (ALG6 alpha-1,3-glucosyltransferase) | protein interactions | 29929 | 29 | 14 | 19454 | 5460 |
CCDC47,SCN3B,TP53,CRELD1,GNAI3,PTGFR,RIT1,RPA2,LRP10,DPEP1,IMMP2L,NDFIP1,LPAR1,TAX1BP1 |
| 1.637e-02 | -4.11 | SERPINB1 (serpin family B member 1) | protein interactions | 1992 | 63 | 26 | 19454 | 5460 |
XPO1,NFYA,TRAPPC4,STK11,UBE2H,TES,GTF2B,CELA3B,UQCRH,EIF4H,MB21D2,PRKCE,TAX1BP1,MAP1LC3B,SOX2,CDC42,RAF1,PIH1D1,RPA2,PICALM,METTL14,STX17,HSPA8,RPA3,RAD21,ATG4A |
| 1.637e-02 | -4.11 | C1qbp (complement component 1, q subcomponent binding protein) | protein interactions | 12261 | 63 | 26 | 19454 | 5460 |
CAV1,CHCHD3,ERLIN1,PHB1,VDAC2,LSM14B,ATP5F1A,STOML2,CLPX,FLOT1,CMAS,POLDIP2,CHMP2B,PHB2,CHCHD2,RBBP7,STOM,CHMP1A,SLC12A2,ATP5PO,ERLIN2,LBR,UQCRC1,MRPL47,ETFB,NDUFA2 |
| 1.637e-02 | -4.11 | NPAT (nuclear protein, coactivator of histone transcription) | protein interactions | 4863 | 63 | 26 | 19454 | 5460 |
ZFP1,H2AX,ASB8,SUPT5H,HINFP,H2AJ,RNF41,RAD21,COIL,ASF1A,RBBP7,KDM1A,NUP50,NLE1,MRFAP1L1,ASB7,RC3H2,GAPDH,CREBBP,MYC,VPS39,KLF9,RBBP4,SNRNP40,GATAD1,PHF21A |
| 1.637e-02 | -4.11 | FCHSD2 (FCH and double SH3 domains 2) | protein interactions | 9873 | 63 | 26 | 19454 | 5460 |
SNX33,MNS1,MRFAP1,RINT1,ATPAF2,HSPA5,RIGI,ENKD1,LDOC1,WASL,BORCS6,CASK,SRP72,HGS,CFAP36,HSP90AB1,FCHSD2,HOMER1,HTRA1,LCA5L,CCDC85B,GPRASP2,CSK,VCPIP1,SERTAD3,CCT2 |
| 1.637e-02 | -4.11 | TMEM120A (transmembrane protein 120A) | protein interactions | 83862 | 63 | 26 | 19454 | 5460 |
UPK1A,STX1A,KDSR,SCN3B,FBXO7,PPP1CC,ATP5F1B,B4GALT3,TNFSF18,CD1A,ESR2,SERINC1,TSPAN18,CTLA4,PRKCA,ARL15,CRELD1,TMEM14B,SNAP29,YIPF3,HCST,TMX2,CXCR4,RUSF1,ATP5PF,CYBRD1 |
| 1.638e-02 | -4.11 | GATAD2B (GATA zinc finger domain containing 2B) | protein interactions | 57459 | 218 | 76 | 19454 | 5460 |
EZH2,STMN2,NGB,DISC1,MTA2,SMARCB1,MOB3C,MTA3,TP53,NDUFA2,SOX2,H2AX,SAP30,H3C1,RBBP7,ZBED1,CDK2AP2,ASF1A,TRIM37,PHF1,FOXP4,GPSM3,KPNA1,BRD3,FOXP1,DPY30,CSNK2A1,EIF3D,BRMS1L,SUMO2,TOP1,SHPRH,ZBTB2,HMG20A,SIN3A,H2AZ1,MYBL2,EED,GATAD1,RPA2,KLF3,FOXS1,EMC9,TCF19,HEXIM1,ACTL6A,WDR77,MBD3,FOXP2,RPA3,PML,RNF113A,BRCA1,TXNIP,SMAD2,FAM219A,CDC16,SMARCA5,MYC,CDKN2D,HNRNPC,RUNX1,SMARCE1,FBXO44,CEP70,AR,RBBP4,ACTB,TRAF1,ESR2,CCNF,PHF12,ZBTB33,CSNK2B,TRIM27,MACROH2A1 |
| 1.643e-02 | -4.11 | GTF3C4 (general transcription factor IIIC subunit 4) | protein interactions | 9329 | 183 | 65 | 19454 | 5460 |
MYC,CUL3,SUB1,TUFM,MCM4,AR,LMNB1,IVNS1ABP,BRCA1,PAPSS2,FAIM,ZMYM2,MSN,MACROH2A1,DAPK1,FBXO22,SRPK2,ESR2,VIRMA,RPL22,SYK,CCND1,EHD1,FOXS1,HEXB,SNRK,PML,MTDH,RNF113A,UFL1,METTL22,COIL,IFI16,API5,DDRGK1,H2AC4,AGR2,SNRNP70,POU5F1,USP15,ZNF688,PHB1,EED,RPS16,POLR3F,FZR1,PRNP,SUMO2,TOP1,EGLN3,RAF1,HEXA,TP53,EZH2,CDK8,CBX3,RBPJ,RAD1,MOB3C,EHD4,H3C1,HNRNPK,XPNPEP1,MCM6,GTF3C3 |
| 1.647e-02 | -4.11 | pyrophosphatase activity | molecular function | GO:0016462 | 797 | 266 | 18094 | 5411 |
ABCC5,ATP1A1,NUDT4,NUDT3,HSP90AA1,AGAP1,RGS6,TOR1B,GFM2,RAB1A,KIF1C,RAB18,RAB3D,MCM4,GNG5,RAB35,ATP2B4,RGS5,XRCC5,DHX15,APTX,SMARCA5,NUDT7,RIT1,RAP1A,ARL4A,ERAS,CDC42,DRG2,PSMC1,GNAQ,GNGT2,RHOH,RAB9B,G3BP1,ARHGAP5,NKIRAS2,PSMC4,RHOG,ARL10,RHOJ,DHX38,RAB39B,RAB29,ARL5B,HSP90B1,RASL12,RAB5A,RAC2,HSPD1,KIF2A,ATP6V1G1,MTG2,NTPCR,ARF1,ADPRM,RAB33B,RGS10,RAP2A,RAB19,GNB3,GNG11,HRAS,GNAO1,RALA,RFC4,DHX16,TRIM23,ACTB,ABCE1,TCP1,RAB28,MFN1,ABCF1,RAB27A,EIF4A2,RAN,RAB1B,RAB5C,RAB14,NUDT9,DDX42,PSMC3,GNAI2,ARF4,IFIH1,DDX4,GNB1,RUVBL1,MX2,RUVBL2,RND3,RFC2,RAB6B,PLPP4,GTPBP2,RASL10A,TPPP,TOR3A,MCM6,RAP1B,EIF5B,NUDT16,TWNK,ATP1A2,EEF2,DCTPP1,DRG1,GNAI3,CLPX,MORC2,CCT8,RGS1,RAB9A,MRAS,RRAGB,ATP6V1G2,RAB3B,ARL11,COQ8B,DCP2,ATP5F1A,CLU,ATP6V1A,RASD1,TUBB4B,NUDT12,RAB4A,CFTR,ATP5F1B,RHEB,GNA14,RAB30,SEPTIN7,CCT7,GNL1,MMAA,GNAZ,KIF3B,RAB23,DNM2,DIRAS1,AGAP2,MLH3,MCM8,BCS1L,DDX1,RERG,PLPP6,TUBB,RAB11B,SMC4,NUDT2,DDX39B,DDX39A,GPN2,ALPL,MORC4,ATAD1,HSPA5,SHOC1,DDX50,ATP1A3,MTG1,MMUT,ERCC3,SAR1B,RAP2C,MOV10,NLRP3,FHIT,ATP2C1,RALB,KATNAL1,IFT22,GNA11,NUDT19,NUDT5,MX1,RFC3,HSPA8,SLC25A42,RAB3A,RAB32,GNG10,GFM1,ABCG2,RGS2,RND2,RHOBTB3,DDX23,RABL2B,RAB13,DIRAS2,RAB22A,RHOB,RAB11A,NUDT18,RAB3C,VPS4A,OLA1,NLRP1,NKIRAS1,TUFM,RRAS2,TOR2A,RGS19,DDX5,RHOU,HSPA13,RAB8B,RAB33A,TUBA1B,RASL11A,ATL1,TOR4A,DDX46,DXO,SRPRA,CCT2,RAB2A,RAB40AL,HSPA14,FITM2,HSP90AB1,ABCC2,RRAGA,PSMC5,GTPBP1,VPS4B,KRAS,RAP2B,KIF3C,ENPP4,ENTPD4,RABL3,RASL10B,DNAJC27,EIF4A3,ATP8A1,ARL15,CLPB,THTPA,DHX9,ARF6,RAB6A,MCM3,RAB31,DIRAS3,RAB37,NUDT1,ABCB1,RFC5,SEPTIN6,ARL6,ARL4D,RHOBTB1,RIGI,GNG3,SRP54,SMCHD1,EEF1A1,CCT5,ENTPD3,RIT2,ABCB9 |
| 1.649e-02 | -4.10 | SIGIRR (single Ig and TIR domain containing) | protein interactions | 59307 | 16 | 9 | 19454 | 5460 |
ENO2,TLR4,TRAF6,LGALS8,TLR9,TLR5,RPN1,HNRNPL,KRAS |
| 1.649e-02 | -4.10 | SYTL5 (synaptotagmin like 5) | protein interactions | 94122 | 16 | 9 | 19454 | 5460 |
ACTA2,RAB11A,RAB27A,RAB6A,YIF1A,CEP70,TRIM54,RAB3B,RAB3A |
| 1.649e-02 | -4.10 | DNPH1 (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) | protein interactions | 10591 | 16 | 9 | 19454 | 5460 |
PRDX1,CCNF,DDIT4L,SSU72,DSTN,PRNP,KLF3,DNPH1,ZNF593 |
| 1.649e-02 | -4.10 | STOX2 (storkhead box 2) | protein interactions | 56977 | 16 | 9 | 19454 | 5460 |
YWHAB,VIRMA,YWHAZ,DYNLL1,YWHAG,YWHAH,DNAL4,CSNK1E,SFN |
| 1.649e-02 | -4.10 | SAPCD1 (suppressor APC domain containing 1) | protein interactions | 401251 | 16 | 9 | 19454 | 5460 |
TCAP,CTNNA2,RANGRF,CTNNA1,EFHC1,ARHGAP21,APEX1,HGS,CTNNB1 |
| 1.649e-02 | -4.10 | MX2 (MX dynamin like GTPase 2) | protein interactions | 4600 | 16 | 9 | 19454 | 5460 |
RAF1,CFTR,EZH2,AK2,TXN,CGAS,TXNDC12,MX2,FXN |
| 1.649e-02 | -4.10 | REG3A (regenerating family member 3 alpha) | protein interactions | 5068 | 16 | 9 | 19454 | 5460 |
ACTA2,CMSS1,CSK,REG1A,MDFI,KLHL22,ACTB,SDC2,CMAS |
| 1.649e-02 | -4.10 | EDARADD (EDAR associated via death domain) | protein interactions | 128178 | 16 | 9 | 19454 | 5460 |
TAB2,SDCBP,SHPRH,TRAF6,NTAQ1,TRAF2,UBE2I,SUMO1,CUL3 |
| 1.649e-02 | -4.10 | HHV8GK18_gp78 (ORF69) | protein interactions | 4961444 | 16 | 9 | 19454 | 5460 |
PTPN11,GPX4,ISCA2,CMC4,MTPN,FN3KRP,CTBP1,MINDY3,MAT2B |
| 1.649e-02 | -4.10 | PPP4R4 (protein phosphatase 4 regulatory subunit 4) | protein interactions | 57718 | 16 | 9 | 19454 | 5460 |
HNRNPL,YWHAZ,PPP4C,YWHAB,HSPA5,SFN,YWHAH,HAPSTR1,YWHAG |
| 1.649e-02 | -4.10 | PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1) | protein interactions | 79912 | 16 | 9 | 19454 | 5460 |
LSM2,LSM4,KRAS,DHX16,RIT1,ILF2,UPRT,RPA3,CFTR |
| 1.649e-02 | -4.10 | ZNF395 (zinc finger protein 395) | protein interactions | 55893 | 16 | 9 | 19454 | 5460 |
YWHAZ,WASL,FBXW11,H2AC4,YWHAB,TOP3B,YWHAH,YWHAG,SAP30 |
| 1.649e-02 | -4.10 | FZD4 (frizzled class receptor 4) | protein interactions | 8322 | 16 | 9 | 19454 | 5460 |
FAM241A,RAB5A,DVL2,DLG1,TSPAN15,DLG4,CERS6,NDP,CD47 |
| 1.649e-02 | -4.10 | BZLF1 (protein Zta) | protein interactions | 3783744 | 16 | 9 | 19454 | 5460 |
RPA2,CAND1,LMNB1,H2AB1,RPA3,SSBP1,HNRNPC,XRCC5,CUL2 |
| 1.649e-02 | -4.10 | C1orf122 (chromosome 1 open reading frame 122) | protein interactions | 127687 | 16 | 9 | 19454 | 5460 |
STAU1,SNX2,SGF29,RBBP7,MRPL12,TRAF2,INSYN1,LURAP1,SNAP29 |
| 1.650e-02 | -4.10 | NTNG1 (netrin G1) | protein interactions | 22854 | 102 | 39 | 19454 | 5460 |
GSTK1,VPS26A,NAA50,BTF3L4,NT5C2,POR,SNX5,HDHD5,CYRIB,PTPN1,TRMT6,RAP1B,SNX12,SNX2,SNX3,SNX1,F11R,DUSP3,FAM162A,ARHGAP1,TOMM22,UBLCP1,GNPNAT1,EHD1,MAP2K1,PICALM,RPN1,VAMP2,HGS,OXSR1,NDUFA12,KLC2,PPME1,NAE1,EHD4,TTC1,PGA4,STK26,GNL1 |
| 1.651e-02 | -4.10 | spliceosomal complex assembly | biological process | GO:0000245 | 83 | 34 | 18204 | 5365 |
SRSF1,DDX46,SNRPD1,SNIP1,SNRPG,SF3A1,TXNL4A,RBMX2,SF3B4,LUC7L3,SNRPB,SRSF12,SMN1,USP39,SF3B5,SF3B6,DDX23,SRPK2,KHDC4,SNRPD3,GCFC2,SNRPD2,RBM5,DDX42,PRPF19,SF3B1,DDX1,SNRPB2,SRSF10,SLU7,SNRPA1,SNRPE,DDX39B,CELF6 |
| 1.655e-02 | -4.10 | Intra-Golgi and retrograde Golgi-to-ER traffic | REACTOME pathways | R-HSA-6811442 | 179 | 70 | 10285 | 3229 |
DYNC1I1,RAB30,ARF4,RGP1,KIF3B,ARFGAP1,ARFGAP3,RAB9B,CYTH2,TMED9,COPZ2,PAFAH1B2,NAA35,RACGAP1,SURF4,SYS1,KIF2A,SNAP29,GOSR2,RINT1,RHOBTB3,KDELR1,RAB18,SEC22B,GCC1,DCTN6,RAB6A,GALNT2,RAB33B,BET1L,STX10,DYNLL1,USE1,KLC2,NAPA,DYNC1I2,KDELR2,ARF1,RAB1B,RAB6B,RAB1A,ARCN1,DCTN4,KIF3C,GOLGA5,DCTN3,NAPG,CYTH1,VPS54,CYTH4,MAN1A2,VAMP3,PAFAH1B1,TMED3,USP6NL,STX18,GOSR1,YKT6,COPE,PAFAH1B3,BICD2,STX6,GALNT1,RAB9A,STX5,COG1,KIF1C,NAA30,STX16,TMED7 |
| 1.658e-02 | -4.10 | biological process involved in interaction with symbiont | biological process | GO:0051702 | 118 | 46 | 18204 | 5365 |
STOM,APOBEC3H,SP1,F2,MIR221,PSMC3,RAB5A,MYD88,MIR222,NUCKS1,GAPDH,CDK9,CAV2,SMARCB1,PC,TAF11,IFI27,ZBED1,NLRP6,PLG,CFL1,CCL8,EEF1A1,HSPD1,INPP5K,HSPA8,SAP30BP,PPIB,RAB9A,ZDHHC8,CCL3,MBL2,JUN,PAIP1,CDC42,CAMP,GPX1,PHB1,TUSC2,RAB29,CX3CR1,ROCK2,ROMO1,EP300,SAP30,CCL5 |
| 1.660e-02 | -4.10 | LPAR6 (lysophosphatidic acid receptor 6) | protein interactions | 10161 | 66 | 27 | 19454 | 5460 |
SLC25A24,TMEM184B,LMBRD2,HBB,SEC22A,TNPO2,ZDHHC17,PXMP2,LPCAT3,ARL5B,JAK1,RTN4,NDUFC2,TSPAN15,VMP1,DEGS1,EXOC2,RAB32,SLC38A2,CAV1,SPPL3,ARL6IP5,COG1,ABHD17A,STX10,HYCC1,RPRM |
| 1.660e-02 | -4.10 | DDX49 (DEAD-box helicase 49) | protein interactions | 54555 | 66 | 27 | 19454 | 5460 |
RPS24,PNO1,RPL31,RPA3,KRAS,UFL1,KIAA0408,MIR15A,MIR1-2,OTX2,FEM1A,RPA2,MIR214,ZNF330,APEX1,ESR2,SPPL3,DDRGK1,HNRNPA1,MYC,PSMB2,MIR140,RIT1,STX1A,ATG3,LMNB1,DDX23 |
| 1.660e-02 | -4.10 | ALPI (alkaline phosphatase, intestinal) | protein interactions | 248 | 66 | 27 | 19454 | 5460 |
DHRS7B,GHITM,METTL14,TUBA1A,SLC35E1,MAP1LC3B,HYAL2,RFC3,TOR2A,ART5,TMEM106B,TMEM263,RAB29,PEX3,VMP1,HSPB1,RHOG,RFC5,RHEB,HDAC6,MTG2,RAB39B,VIRMA,EIF4A2,DTYMK,OLFM2,SFXN2 |
| 1.660e-02 | -4.10 | HIBCH (3-hydroxyisobutyryl-CoA hydrolase) | protein interactions | 26275 | 66 | 27 | 19454 | 5460 |
IRF2BPL,GTF2E2,H2AX,SOX2,CENPM,UFM1,NEDD8,PRCP,COX8A,FLCN,HSPA8,LSM12,HNRNPH2,SOD1,HSPD1,CIART,CYP1A1,PRR19,NME2,ETFRF1,CLIC4,MYG1,UMPS,RPL35A,GATD3,CAB39,DSTN |
| 1.660e-02 | -4.10 | B4GALT7 (beta-1,4-galactosyltransferase 7) | protein interactions | 11285 | 66 | 27 | 19454 | 5460 |
CHRNB2,TMEM14B,GINM1,TP53,TMEM59,TMEM106A,YIPF3,SEC62,CCL3,ST7,HSPA5,SLC39A7,RABGGTB,PCNA,TWNK,HFE,YWHAZ,ID1,UPK1A,CDC16,MYC,FAM20C,THOC1,TNFSF18,ESR2,B4GAT1,FUT1 |
| 1.660e-02 | -4.10 | DCC (DCC netrin 1 receptor) | protein interactions | 1630 | 66 | 27 | 19454 | 5460 |
RPS24,RPL28,RPS13,EIF4E,RPS4X,CNOT6L,EIF3E,ANP32B,TRMO,FBP1,TMOD1,EIF1AX,PITPNA,EIF2S2,ALB,EIF4E3,RPS10,SIAH1,EIF2B2,SIAH2,AR,REEP6,RPL23,RPL10A,EIF5A2,TDRD7,NCK1 |
| 1.660e-02 | -4.10 | GNG2 (G protein subunit gamma 2) | protein interactions | 54331 | 66 | 27 | 19454 | 5460 |
TBC1D24,GNA11,STK26,PIK3CG,KCTD17,ADRB2,GABBR1,GNB4,KCTD16,KCTD12,GNAQ,GNAZ,PDCL,PGGT1B,ARMC1,GNB3,GNAO1,RANGRF,GNAI2,GNB1,MRGPRX1,MYC,ADCY2,RHEB,CD81,RRP7A,HAX1 |
| 1.660e-02 | -4.10 | RAD9A (RAD9 checkpoint clamp component A) | protein interactions | 5883 | 66 | 27 | 19454 | 5460 |
RAD1,RPA2,CDK1,TOP3B,FEN1,RFC3,MSH6,RFC2,FBXW7,KRAS,PCNA,TWNK,RFC4,TOPBP1,RIT1,BCL2L1,DNAJC7,BRCA1,POLB,OGG1,AR,FEM1B,RFC5,COPS5,CSNK2A1,PRKCE,CSNK2B |
| 1.660e-02 | -4.10 | PGLS (6-phosphogluconolactonase) | protein interactions | 25796 | 66 | 27 | 19454 | 5460 |
RIGI,IMPA2,SSNA1,EWSR1,HINT2,PRDX6,PEBP1,PLSCR1,RPA3,SOD1,PIH1D1,LMNA,NDUFAB1,SOX2,PGM1,FEN1,DDAH1,CLIC4,NUP35,HDHD3,CCNF,RCHY1,UBE2H,GLOD4,AGR2,MDFI,ACO2 |
| 1.661e-02 | -4.10 | homeostasis of number of cells | biological process | GO:0048872 | 282 | 100 | 18204 | 5365 |
NLRP6,HCLS1,JAK2,SLC11A2,IL2RA,GPRASP2,RAG1,CDK5RAP3,FOSL2,RB1,TUBA1A,SLC25A5,SOX9,KIT,CEBPG,SART3,G6PD,TSPO2,FAS,ATP5IF1,CCR2,VPS54,BPGM,SOD1,RRN3,POLB,KRAS,BAK1,RHAG,TMOD3,CX3CR1,TNFAIP3,CCN3,GPAM,CCR4,HMGB1,MPIG6B,AKT1,BCL6,PKNOX1,MYCT1,HSCB,CCR7,HDAC6,FOXA3,EPO,FSTL1,LYAR,WDR37,GAPT,ARMCX1,RC3H2,SIT1,SFXN1,NCSTN,VEGFA,BAP1,ADGRG1,PMAIP1,NCAPG2,IREB2,EZH2,IL7,MEF2C,KLF1,IL20RB,TRIM10,ZNHIT1,OCIAD2,CHMP5,MAEA,PPP2R1A,EMX1,RPS24,LIPA,RACGAP1,UFL1,LPCAT3,INHA,SLC39A3,NLE1,SOS2,RPS14,RPS17,IL6,TRAF3IP2,BAX,LGR4,CAMLG,RAC2,PRDX2,EXT1,PRDX1,SASH3,AKT3,FOXP3,PTPN11,SMAD5,PDE4B,SLC48A1 |
| 1.664e-02 | -4.10 | PGM1 (phosphoglucomutase 1) | protein interactions | 5236 | 99 | 38 | 19454 | 5460 |
GATD3,CMBL,ENO1,FAH,TENT5C,LDHA,LDHB,ACO2,DNAJB6,SORD,NLRP3,MDH1,PEA15,OAT,EXOC2,GLOD4,GSTO1,PRDX6,EMC2,TXNL1,HSPB2,HSPA8,HINT2,RPA3,SOD1,BAP1,S100B,SAR1B,EMC1,NDUFAB1,CMPK1,FEN1,ARCN1,GSTP1,RPS11,IDH2,CHMP4C,RPA2 |
| 1.664e-02 | -4.10 | B3GAT3 (beta-1,3-glucuronyltransferase 3) | protein interactions | 26229 | 99 | 38 | 19454 | 5460 |
STX6,RAMP3,NOP9,NLGN2,ESR2,MGAT1,CCR2,ARMC6,SYNGR1,SLC30A7,NDST3,S1PR4,LMBR1L,CCNF,PIGK,HNRNPD,SYP,CSGALNACT2,FAM174A,CIAO1,PDE2A,NLGN1,CCR4,SLC31A1,TACR1,TMEM160,TMEM106B,TSPAN15,PLD3,LEMD3,TMEM95,GPR35,SFTPC,SEC62,TMEM106A,TMEM59,HYAL2,SEC22B |
| 1.666e-02 | -4.09 | 14_3_3 | smart domains | SM00101 | 7 | 5 | 9717 | 2575 |
YWHAZ,YWHAH,YWHAB,SFN,YWHAG |
| 1.666e-02 | -4.09 | GS | smart domains | SM00467 | 7 | 5 | 9717 | 2575 |
ACVR1B,ACVR1C,BMPR1B,BMPR1A,ACVR1 |
| 1.668e-02 | -4.09 | peptide hormone receptor binding | molecular function | GO:0051428 | 20 | 11 | 18094 | 5411 |
VIP,GPHA2,JAK2,PTPN11,PTHLH,PSMC5,GNAO1,GNRH2,GNRH1,UCN,LEP |
| 1.671e-02 | -4.09 | regulation of epithelial to mesenchymal transition | biological process | GO:0010717 | 121 | 47 | 18204 | 5365 |
MIR21,MIR519D,MIR149,TGFBR2,MIR221,MIR130A,SMAD2,MIR222,ACVR1,RGCC,GLIPR2,LDLRAD4,EMP2,EZH2,VEGFA,MIR204,TGFB1I1,MIR573,MAD2L2,PTEN,SMAD4,ADIPOR1,GREM1,SDHAF2,SPRY1,MIR590,NOG,DAG1,IL1B,TGFB3,SPRED2,TRIM62,MIR142,FERMT2,MIR379,CTNNB1,MIR145,MIR302B,SFRP1,IL6,SMAD3,TGFB2,EPHA4,MIR144,SDCBP,SPRED1,TIAM1 |
| 1.672e-02 | -4.09 | IRS1 (insulin receptor substrate 1) | protein interactions | 3667 | 136 | 50 | 19454 | 5460 |
EGLN3,PRKCQ,CAV1,RPRD1A,SMAD3,PTPN1,CBL,YWHAB,BCL2L1,IKBKB,SHC1,CSNK2A1,YWHAG,YWHAH,PIK3R1,CD36,KLHL9,FBXO25,PELI1,JAK1,IGF1R,DLG1,GHR,PIK3CA,SOCS3,TOP3B,ROCK1,DYRK1A,VIRMA,ESR2,JAK2,LAMTOR3,TRIM29,CSNK2B,FAIM,FBXW11,YWHAZ,NIBAN2,AKT1,CIAO1,GRB10,PTPN11,CUL3,PIK3R3,SFN,PIK3R2,DVL2,CSNK1A1,CD2AP,ATG16L1 |
| 1.672e-02 | -4.09 | MAGEA11 (MAGE family member A11) | protein interactions | 4110 | 136 | 50 | 19454 | 5460 |
PPM1K,CLP1,TMEM123,STAR,TPM3,CSNK2A1,NOL4,EGLN3,PHYH,PGR,FAM156A,RB1,MGME1,PLCXD3,SPMIP9,PPIF,KIAA0408,SNX20,UTP25,VTA1,ZBTB16,HUWE1,EWSR1,TCEA2,CTTNBP2,DNAJC10,NIF3L1,AR,PDE4B,NTAQ1,ZCCHC12,MLF1,POLR2B,EGLN2,GNPDA1,ZNF655,TRIM27,LMBR1L,WTAP,CCNA2,POLR1D,IL6ST,PRDX3,FAM161A,SKP1,RANBP10,EP300,CCDC106,BIRC2,RBM23 |
| 1.672e-02 | -4.09 | NAV1 (neuron navigator 1) | protein interactions | 89796 | 136 | 50 | 19454 | 5460 |
MAPRE1,FBXW11,YWHAZ,GCC1,PPP1CC,SFN,CCNB1,GPR17,VIRMA,APLNR,PHF21A,AGAP1,TRIM36,RPA2,VAPB,BORCS6,SIPA1L1,INPP5E,DDIT4L,ATG16L1,RNF41,KDM1A,SQSTM1,RTKN,RPA3,YWHAB,MED4,PDCD1,MAP3K14,P2RY10,YWHAH,YWHAG,NDC80,UBXN6,OPRL1,KCTD3,HNRNPL,KRT8,EIF4E2,EEF1AKMT3,HRAS,TBC1D4,DISC1,TOP3B,FKBP8,SRSF12,TRIM37,CD80,TESK2,ERP29 |
| 1.675e-02 | -4.09 | LMTK3 (lemur tyrosine kinase 3) | protein interactions | 114783 | 96 | 37 | 19454 | 5460 |
OLA1,ARF4,SSRP1,ANP32B,PTGES3,ZBTB16,TMEM33,ABCE1,PEBP1,NDUFA4,PLS3,ZNF326,KIF2A,ETF1,RAB6A,TOMM22,UBE2V2,TECR,EIF2S1,PNP,SUMO2,S100A8,EIF2S2,MACROH2A1,AKR1B1,ACAT1,MRPS9,UBE2N,AHSA1,NSA2,GLO1,KARS1,BAZ1B,SMARCA5,MYC,CALR,PYCR2 |
| 1.675e-02 | -4.09 | H2BC12 (H2B clustered histone 12) | protein interactions | 85236 | 96 | 37 | 19454 | 5460 |
PHB1,CCNF,TES,GSK3A,FZR1,NDN,VIRMA,SRPK2,ESR2,CBX5,DPP4,SUV39H1,CD81,BTF3,HDAC6,PSMD14,H2AC4,ICAM1,HNRNPD,MAP1B,HIRA,PPM1G,PRKCB,CLK1,HDAC5,HAPSTR1,HMGN4,TNF,MEPCE,FBP1,ELK4,METTL14,CBX3,EZH2,WTAP,NUPR1,HEXIM1 |
| 1.675e-02 | -4.09 | ZNHIT2 (zinc finger HIT-type containing 2) | protein interactions | 741 | 96 | 37 | 19454 | 5460 |
EIF2D,PTGES3,POLDIP2,HSCB,TSSC4,KRAS,RUVBL1,DNAAF10,RPAP3,RUVBL2,FBXO3,NCDN,TCOF1,JAKMIP1,POLR2C,SART3,PIH1D1,USP39,RPAP2,CD2BP2,DHX38,DKC1,POLR2B,RAPGEF5,SNRNP40,LMBR1L,WDCP,PFDN2,RIT1,DDX23,KIAA1143,ECD,XPO1,INSYN1,UBXN6,PRPF19,CUL3 |
| 1.675e-02 | -4.09 | PDIA5 (protein disulfide isomerase family A member 5) | protein interactions | 10954 | 96 | 37 | 19454 | 5460 |
LCN9,PPP1R2,LASP1,GPIHBP1,TGIF2LX,BIRC2,EP300,PDIA6,MME,TMEM106B,CCL18,POLR2G,RPN1,TRAF2,CCL3,ATG16L1,RAF1,TOP3B,TP53,CDC5L,HNRNPL,G0S2,MBL2,SEC61B,FUBP3,PSMB4,SDF2L1,COX16,PSMD14,ESYT1,CUTA,GGH,PRPF19,RNASET2,CSK,MDFI,FAM20C |
| 1.675e-02 | -4.09 | KDM6B (lysine demethylase 6B) | protein interactions | 23135 | 96 | 37 | 19454 | 5460 |
CRKL,ACACA,PSMC3,GSTP1,PNMA2,CBX3,SMAD1,PRMT2,WDR77,TOP3B,PSMC4,SSRP1,AHCYL1,PSMC1,FARSA,MCMBP,RPIA,H3C1,PSMA1,PDIA6,KPNA1,SMAD2,SMAD4,TUBG1,GMPS,TPM3,KARS1,CREBBP,VIRMA,RPS27L,PRMT5,GANAB,CSNK2B,XPO5,SNRPD1,SMAD3,WDR6 |
| 1.675e-02 | -4.09 | TSHR (thyroid stimulating hormone receptor) | protein interactions | 7253 | 96 | 37 | 19454 | 5460 |
HNRNPA1,TIMP1,FBXO7,CD81,CRADD,MLF1,PIK3R1,CALR,PTDSS1,GNAO1,OAF,ADGRG1,PTK7,MOG,MID1IP1,JAK2,GNAI2,OS9,TUBB,ACTB,TUBA1A,TSHR,ADORA1,NEU1,GNAQ,GNAI3,TCP11L1,SPSB3,FGFR1,JAK1,RABAC1,ART5,PC,GNA11,HSPA5,LAMB2,ADRB2 |
| 1.675e-02 | -4.09 | FYCO1 (FYVE and coiled-coil domain autophagy adaptor 1) | protein interactions | 79443 | 96 | 37 | 19454 | 5460 |
RCCD1,RPA3,SLU7,RAB9A,EP300,ADO,KDM1A,SGF29,PAX6,POLDIP3,CCAR1,TOP3B,RAF1,BORCS6,MAP1LC3B,RPA2,LMNA,CCDC71,MAP1LC3A,TCP1,CCT7,ESR2,VIRMA,TMPO,PRMT6,LAMP2,MOV10,KXD1,IQSEC1,XPO1,AGR2,FTSJ3,LAMTOR1,CCT2,SMAD4,MAP4,STK11 |
| 1.677e-02 | -4.09 | CTH (cystathionine gamma-lyase) | protein interactions | 1491 | 69 | 28 | 19454 | 5460 |
SCG3,MTPN,NTAQ1,GMDS,LMBR1L,PAPSS2,CCNF,ENO2,PREP,PTCRA,SGTA,CTBP1,RPA2,PLAA,TP53I3,GHITM,GUCD1,CAPN2,PIH1D1,RDH12,RPE,SLC25A32,YTHDF1,HSPE1,ARHGEF39,FBXW7,LUM,RPA3 |
| 1.677e-02 | -4.09 | PABPC3 (poly(A) binding protein cytoplasmic 3) | protein interactions | 5042 | 69 | 28 | 19454 | 5460 |
CRY1,SOD1,PEBP1,BRIX1,MEPCE,EIF4E,RUVBL1,CFTR,CDK7,DUSP1,EEF1A1,GTF3C4,TP53,HEXIM1,MTA2,TENT5D,CHMP4C,TFCP2,GAB1,SRC,CSTF3,TRIM54,FBXO7,PAPOLA,CALR,TMOD2,MGMT,RC3H2 |
| 1.677e-02 | -4.09 | negative regulation of DNA-templated transcription | biological process | GO:0045892 | 1256 | 404 | 18204 | 5365 |
NACC2,MSX2,WDR82,DNAJB6,SFN,IFNA2,CDC73,FABP4,PLCB1,KCNIP3,HDAC3,ZBTB16,ZNF24,E2F6,RPL10,BAP1,CD36,FOXD3,POU5F1,TCF21,LYAR,MAD2L2,PAX6,SIN3A,IFI27,ZBTB33,TXNIP,WNT10B,FOXS1,MTA3,ZNF263,PPARA,SMARCE1,COPS2,JUN,HMX1,ENO1,FOXP3,DMAP1,CBX3,ZBTB2,USP2,ID4,RFX5,BAHD1,SOX21,MAGEC2,FOXP1,NKX3-2,LDB2,PHF21A,CCND1,HIRA,UBE2D1,AR,TRIM24,NCOA5,CREBZF,LMO4,CRY1,DEDD,E4F1,MCPH1,PHC1,MAF1,TSG101,NR1H2,USP3,STAT1,PRMT5,DUSP26,SMAD4,ZMYND11,EID2B,GMNN,NOP53,SIAH2,CTNNB1,RBBP4,SP2,VDR,TXN,MAX,BACH1,MXI1,CCND3,SAP30,EP300,DR1,CNOT2,TCF23,CALR,OVOL1,SIRT7,SOX14,ELK4,CIPC,MYT1L,IFI16,NIBAN2,CTNNBIP1,CRYM,TCEAL7,GTF2IRD1,NR2E1,CUL3,NR0B1,IRF1,BRMS1,INSM2,YWHAZ,MAGED4B,FOXP2,DRAP1,MTA2,VEGFA,CCAR1,SATB1,NSMCE3,PRMT6,DNAJB4,SOX3,MECP2,HEXIM1,EID1,PHB2,ZNF175,HNRNPA2B1,ATF4,LEP,HNRNPK,FASLG,SQSTM1,H1-3,KLF3,CCDC85B,ELK3,SMARCA5,PPID,PDCD4,HOXB8,MEF2A,SUPT4H1,ETV6,BIRC5,ZBTB5,CBX7,APEX1,IFNG,PIAS1,XRCC5,ZBTB39,PLAGL1,C1D,CD38,GADD45A,TRAF6,ZBTB25,NFKB1,SNAI3,IRF2BPL,HCLS1,PSPC1,PSMC5,POU1F1,PML,PDE2A,CIART,NKX3-1,MAGEB1,ATF3,NOG,HDAC6,SGF29,CCAR2,NR1I3,SETD5,MACROH2A2,HNRNPL,KLF10,MAGEA4,IRF2BP1,RASD1,NIF3L1,NR2F6,MAGEB10,SCML2,SMAD3,DUSP22,ZGLP1,UBE2I,ZHX1,SCML1,ZBTB42,PSEN1,NKRF,LILRB4,THAP1,BEND6,PKIG,RUNX1,ZMYM2,GFI1,WWP1,SMAD2,BRCA1,IL4,VGLL4,CBFB,BEND5,LANCL2,MEF2C,ING2,DKK3,RUVBL2,MEPCE,RBBP8,TRIM11,CAV1,RBFOX2,ZBTB17,CSF2,SMAD5,HEY2,EED,BARX2,IRF3,TGIF2,NFIL3,CDK5R1,KLF12,MAGED2,ID1,HNF1B,INPP5K,OSR2,MYC,SFRP1,FLCN,CREB1,MAGEH1,CRYAB,RORB,RPS14,MOSPD1,WWP2,DLX1,SNAI2,DICER1,MAFG,IKZF5,IGBP1,DLG1,DHRS7B,TRIM22,TADA3,SOX9,TOB2,ZNF174,SAP30L,HDAC5,CTBP1,PRMT2,IRF8,SHC1,SUMO1,TWIST2,IRF7,NR1I2,KDM1A,ZBTB26,TRIM29,MACROH2A1,ZNF177,THAP7,STAT6,RNF8,MBD3,MTDH,CREBBP,BHLHE40,PROX1,ZBTB18,ZNF345,GREM1,HCFC2,GCLC,TRIM37,IRF2,SOX2,DKK1,HSBP1,RERE,PCNA,RING1,TLE1,ZBTB38,OTUD7B,MXD1,NCK1,NOTCH2,RLIM,MIDEAS,RBM15B,PPARG,RPL23,BTG2,ZBTB6,CDKN1B,IMPACT,SUV39H1,SLA2,SUFU,ESR2,EZH1,EZH2,ZNF692,NR4A2,EPO,ZNF668,EGR1,ZBTB14,CNOT7,KLF4,PAX9,TGIF2LX,POLE3,CDK6,NONO,DDIT3,TRIM27,FGFR1,ATXN1L,NKAP,PCGF2,HELT,SAP18,SIX5,HSPA8,ZNF451,VPS72,MITF,DDX5,PCGF6,UBE2D3,SDCBP,TAF7,MDM2,TP53,MAEL,CGGBP1,FOXC2,H1-5,ZHX3,TFDP2,LDB1,EID2,PHF12,NAB1,ZBTB45,SPINDOC,FBXW11,DAP,RB1,CITED1,PSMD10,SUPT5H,RIOX2,NDN,MDFI,SDR16C5,KDM2A,HINFP,GABPA,FBP1,PKIA,ZNF304,HMGB1,CXXC5,HMG20A,BCL6,PFDN5,HEXIM2,CDK5,NKX6-2,TAGLN3,MSX1,CBX5,FOXP4,PHB1,ING1,TRIM6,HMGA1,ADIPOQ,TNF,RBBP7,LBH,SRSF2,BRMS1L,NAB2,FERD3L,YAF2,XCL1,RBPJ |
| 1.677e-02 | -4.09 | CYFIP1 (cytoplasmic FMR1 interacting protein 1) | protein interactions | 23191 | 180 | 64 | 19454 | 5460 |
MYC,CUL3,AR,SLC1A3,PPP1CC,YWHAZ,RHOB,UBE2H,CCNF,CTNNA1,RHOJ,ACTB,YES1,FBXO22,NCKAP1,GNB1,SRC,VIRMA,ESR2,ATG16L1,TPT1,CDC42,RND2,CFTR,RPA2,CSNK1G3,PIH1D1,CSNK1A1,BAP1,RHOU,RPA3,HSPA8,FXR2,CYFIP2,STAU1,WASF3,WWP2,COPS5,YWHAG,YWHAH,STK4,CTNNB1,RHOG,NCK1,YWHAB,RAB35,HRAS,RAC2,ARF6,ZNF511,NYAP2,RHOH,CGAS,INSIG2,ARHGAP12,MAP1LC3B,EZH2,BZW2,MOB3C,PCNA,ACTR1B,UBE3A,KRAS,ROCK2 |
| 1.677e-02 | -4.09 | PTPN13 (protein tyrosine phosphatase non-receptor type 13) | protein interactions | 5783 | 180 | 64 | 19454 | 5460 |
ESR2,VIRMA,RHOJ,GSK3A,PHF21A,PTEN,CCNF,CTNNA1,NFKBIA,NTRK3,EPHA2,CRHR1,FAS,BEX3,FBXW11,YWHAZ,RHOB,DNAJC5,SFN,CUL3,RGS2,KDM1A,STAU1,STK26,RHOU,RPA3,RTKN,ARL15,RPA2,FGFR1,CDC42,SIPA1L1,RND2,ATG16L1,INPP5E,EGLN3,STX6,DIRAS3,CAV1,HNRNPL,KCTD3,RHOH,GJA1,RAB35,DNM2,EIF4E2,YWHAB,STYK1,YWHAG,YWHAH,CTNNB1,ZCCHC10,RIGI,FLOT1,EPHA4,KRAS,EFNB1,NTRK2,MRFAP1L1,GHR,RND3,PDLIM4,FASLG,RAF1 |
| 1.677e-02 | -4.09 | MYOD1 (myogenic differentiation 1) | protein interactions | 4654 | 180 | 64 | 19454 | 5460 |
ID1,CASP12,SMAD4,SUV39H1,BCL7C,TLE1,MDFI,TCF21,BRMS1L,TSC22D3,RB1,PHB1,FBXO32,SMAD3,PSME2,ELSPBP1,CBFB,NUPR1,POLR2G,SMARCB1,BTG1,ID4,EZH2,JUN,CDK4,AP1M1,PAGR1,H3C1,HUWE1,ZNF609,BCL9,RING1,BHLHE40,MEF2C,SETD7,HSP90AA1,SP1,SMARCE1,RUNX1,TAF5L,CREBBP,ESR2,MORC4,PSMD4,TRIM24,PRMT5,TRIM27,MIDEAS,CIB2,MID1IP1,CREB1,IFRD1,PRKCA,LMO4,SETD3,SS18,MEF2A,PHB2,SGF29,YAF2,EP300,DDX5,SMARCD3,BAP1 |
| 1.681e-02 | -4.09 | regulation of blood pressure | biological process | GO:0008217 | 187 | 69 | 18204 | 5365 |
TACR1,ADRB3,UTS2,ADM2,EMP2,PRCP,MIR17,ATP1A2,CARTPT,SOD1,AR,CNR1,ENPEP,PPARG,HBB,NCALD,MKKS,MECP2,EDNRA,GNB3,OR51E2,CYP11B1,UTS2R,OPRL1,GNA11,ASIC2,BMPR2,UCN,CMA1,CHGA,GSK3A,KCNJ8,SCPEP1,REN,ADORA1,ADRA1A,APLN,ATP6AP2,EXT1,NPY1R,RASL10B,CYP4F12,DDAH1,BRS3,COMT,NPY,PPARA,ADRB2,VEGFC,DRD3,GPR37L1,LEP,EMILIN1,ADRB1,SMAD3,CYP11B2,SNX5,ADIPOQ,ACTA2,TNF,SOD2,TACR3,OXTR,AVPR1B,COL1A2,NPR2,IER3,AGTRAP,ATP1A1 |
| 1.683e-02 | -4.08 | Pathways in cancer | KEGG pathways | hsa05200 | 395 | 156 | 7161 | 2463 |
HRAS,FZD6,DVL2,GNG13,ROCK2,NFKBIA,BIRC5,PRKACB,PML,ITGA6,GNA11,TGFB2,ITGAV,HSP90AB1,GNB4,TP53,GNAQ,LPAR2,PRKCA,TFG,LPAR6,CUL2,AR,CDKN1B,GNG10,RASGRP2,CTNNB1,CTBP1,TRAF6,LAMB2,FAS,TGFBR2,CXCR4,MYC,HSP90B1,GNG3,FZD4,GNB3,MSH6,CTNNA1,TRAF1,FGF13,CCND1,IKBKB,FASLG,MAPK10,BCL2L1,CRKL,MDM2,CREBBP,FGF22,MAX,TGFB3,GNAI3,AKT1,PLCB2,SMAD3,RALA,PIK3R2,JUP,LPAR1,PIK3R3,WNT10B,GNG5,EGLN3,ZBTB16,SOS2,FGF7,ROCK1,IGF1,FGF23,NKX3-1,VEGFC,CBL,GNAI2,WNT2,PTGER4,CKS2,RUNX1,ITGA2,WNT7A,EP300,SMAD4,RALB,CXCL8,RAF1,RB1,PTGER2,IGF1R,JAK1,VEGFA,HHIP,GNG7,CDK6,FOS,FZD3,ADCY3,MET,ELOC,FGF16,HSP90AA1,GNG12,FGFR1,RXRG,SMAD2,EDNRA,IL6,STK4,DAPK3,MAP2K1,ADCY2,SLC2A1,FGF12,NFKB1,KLK3,GNB1,AKT3,FGF3,RASGRP3,PLCB1,CKS1B,MMP9,BIRC2,TRAF2,CTNNA2,KRAS,PTEN,TPM3,PIK3R1,GNGT2,CDC42,FGF17,PPARG,RAC2,FGF1,BAD,FGF10,PTGER1,PIK3CA,CXCL12,BAX,DAPK1,STAT1,GSTP1,JUN,AKT2,MITF,KIT,GNG2,CDK4,GNG11,SUFU,STAT5A,PRKCB,EGLN2,CDKN1A |
| 1.684e-02 | -4.08 | DNA damage response | biological process | GO:0006974 | 767 | 253 | 18204 | 5365 |
POLR2I,SFN,RNF113A,PSEN1,NUDT1,DGCR8,RPS27L,HTRA2,MDC1,TNFRSF1B,HDAC3,ZMPSTE24,GFI1,GTF2H4,UBE2B,BRCA1,MCL1,CDKN2D,PMAIP1,BABAM1,LIG3,RMI2,ING2,GNL1,CDKN2AIP,RUVBL2,MAD2L2,RBBP8,CDIP1,BCL2A1,MGME1,MLH3,APTX,PPP4C,IRF3,SETD7,SLX1A,TENT4A,UBE2A,TOP3B,ACTL6A,MIF,MORC2,CHCHD6,SHPRH,CDK1,DMAP1,CBX3,RCHY1,MYC,BAX,CSNK1E,IER3,FZR1,CETN2,ZSWIM7,NUPR1,TDP1,FAAP100,IMMP2L,POLD4,MYO6,DNTT,FOXP1,MCM6,UBE2E2,DYRK2,DDX1,TOPORS,CCND1,PHF1,MSH6,UBE2N,CDK7,PTTG1,SUSD6,AATF,HPF1,CSNK2A1,POLL,FEN1,CBL,BAZ1B,CDK5RAP3,PAGR1,ASF1A,CRY1,PAXX,BAD,NUCKS1,SUMO1,SMCHD1,BCL2L1,MORF4L1,NABP1,IRF7,PPP5C,USP3,CDC5L,KDM1A,PRPF19,MACROH2A1,AP5S1,RNF8,DDIT4,RPL26,MCM8,INO80E,TANK,UBE2V1,RFC2,MSL2,RMI1,CDC7,UBE2V2,RNASEH2C,RPA3,NOP53,DYRK1B,BAK1,PCNA,SHLD1,BACH1,ZBTB38,CRIP1,EP300,UBE2W,RFC3,POLB,BOK,SIRT7,GTF2H5,IFI16,UFL1,TFIP11,NBN,BTG2,PIK3R1,CDKN1B,MIR193A,SSRP1,SUV39H1,SESN2,TERB2,ALKBH2,VRK1,SAMHD1,SMUG1,MNAT1,RAD21,PRMT6,NSMCE3,ZNF668,HMCES,CHCHD4,RRM1,FANCG,DCLRE1C,HUWE1,ZMAT3,PTPN11,NONO,ALKBH3,POLE3,TFPT,MCM3,EYA3,DDIT3,GTF2H2,MGMT,RAD1,NRDE2,WRAP53,SMARCA5,ARMT1,OARD1,APEX2,SOD2,MIR34A,MCM4,UBE2D3,ASCC1,GNB1L,MPG,MACROD1,MDM2,MEIOB,DTL,VCPIP1,ERCC3,APEX1,TP53,MAEL,NHEJ1,PSMD14,XRCC5,CTLA4,PPM1D,ZDHHC16,GADD45A,TRAF6,RAD23B,NAE1,SPINDOC,H2AX,CRADD,CGAS,OGG1,MAP2K6,H2AC25,KIN,CDK9,PML,RFC4,USP16,CDKN1A,CIDEB,POLDIP2,NKX3-1,BCCIP,FBXW7,KDM2A,HINFP,PCLAF,STK11,PYCARD,BATF,CCAR2,RINT1,HMGB1,STUB1,BCL6,INO80C,EPHA2,TOPBP1,TEX12,TAF9,POLD2,RFC5,KMT5B,CBX5,FBXO31,RUVBL1,TEX264,RPA2,CINP,RPS3,EGLN3,DCUN1D5,TNF,EXD2,GINS4,PARP2 |
| 1.686e-02 | -4.08 | neutrophil migration | biological process | GO:1990266 | 66 | 28 | 18204 | 5365 |
IL1B,CXCR1,IRAK4,PPIB,SYK,CCL3,CKLF,EMP2,PIK3CG,CXCL1,PDE4B,CXCL3,JAML,CXCL13,S100A8,TGFB2,FCER1G,XCL1,CXCL9,CXCL10,LGALS3,DPEP1,SRP54,CXCL8,CXCL11,PPIA,SELENOK,JAGN1 |
| 1.686e-02 | -4.08 | ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6) | protein interactions | 9459 | 93 | 36 | 19454 | 5460 |
SH2D1A,RAC2,TMEM108,PNMA1,SMAD3,SSBP1,SLAIN2,TRIM54,RHOJ,YWHAG,YWHAH,GPRASP2,TAX1BP3,BMPR1B,MED4,NCKIPSD,CBL,SMAD2,ICAM1,NCK1,RABGGTB,RHOU,ARHGEF6,PFDN1,SKP1,TGFBR2,PRDX3,RBM38,CDC42,TRAF2,SMAD1,ATG16L1,LPXN,GIT2,PAK2,HBB |
| 1.686e-02 | -4.08 | WRAP53 (WD repeat containing antisense to TP53) | protein interactions | 55135 | 93 | 36 | 19454 | 5460 |
RCCD1,PRPF4,CCT8,EP300,RBBP7,KRAS,CDK20,CRYL1,NHP2,MDC1,PTGES3,RAF1,TOP3B,TP53,CCT5,H2AX,SAMM50,VAC14,RNF8,PTPN1,SRSF1,FAM43A,ARHGAP25,RAP1B,TUBB,TCP1,DKC1,CNTROB,TRMT61A,ESR2,CCT7,APEX1,HSPA14,ATG7,CCT2,STK24 |
| 1.686e-02 | -4.08 | UTP25 (UTP25 small subunit processome component) | protein interactions | 27042 | 93 | 36 | 19454 | 5460 |
RPA2,DMAP1,NUPR1,AP2S1,IMP3,ATP5PB,TRIM62,IMP4,CHCHD2,H1-6,AATF,UTP25,MRPL20,AHCYL1,PTGES3,EIF3E,SIRT7,MAPKAPK3,PPAN,RPA3,RPS24,MPHOSPH10,MRPL18,CDKN2AIP,UBE2H,AP2A1,MSTN,CDC16,MYC,CEP70,PRPF31,MED17,VIRMA,JUNB,AP2M1,SYT2 |
| 1.686e-02 | -4.08 | TEX11 (testis expressed 11) | protein interactions | 56159 | 93 | 36 | 19454 | 5460 |
BORCS8,SH3GLB2,STMN2,NEFL,LSM2,KIAA0408,CDKN1A,SUPT5H,DUSP21,PIAS1,CCND3,CNOT7,MRFAP1,CLK1,EFHC1,GPSM3,MRFAP1L1,GRXCR1,EXOSC1,SHOC1,USP15,TOPBP1,MEF2B,CENPP,MORF4L1,CDKN2D,PPP1R18,FAM156A,SPPL3,BRMS1L,SPMIP5,KCTD10,TSG101,CXCL14,MYEF2,DUSP6 |
| 1.686e-02 | -4.08 | ARHGEF12 (Rho guanine nucleotide exchange factor 12) | protein interactions | 23365 | 93 | 36 | 19454 | 5460 |
PSMD6,FZR1,ESR2,VIRMA,TRMT61A,PTP4A3,MALSU1,SH3BP4,EEF1AKMT3,SSBP1,KRT8,GSK3A,MYO6,RHOB,RCL1,CBL,LDHB,CUL3,PSMD3,CSK,UBXN6,HNRNPA1,DEPDC1B,LPAR1,ERLEC1,SEM1,PRDX4,FLOT1,IGF1R,CLK1,LPAR2,CSNK1A1L,VAPB,GNAQ,SMARCB1,CDC42 |
| 1.686e-02 | -4.08 | positive regulation of cell adhesion | biological process | GO:0045785 | 486 | 165 | 18204 | 5365 |
CYRIB,PDCD1LG2,RHOH,CRKL,DPP4,CCL19,EFNB1,AIF1,FOXC2,IL2,CCR2,TGFBR2,CCL25,NLRP3,TRAF6,LDB1,PRKCA,CHST2,XBP1,CCL21,BAD,ILK,TESK1,PRKCE,RAG1,NRP1,CCL28,ICOS,TNFRSF14,IL2RA,JAK2,LIMS2,DISC1,CCL2,AGER,GFUS,PYCARD,TNFSF18,ITGA2,DUSP10,POLDIP2,DUSP26,EMILIN1,S100A10,CDH13,CCR7,AGR2,BCL6,AKT1,CXCL12,NDNF,IL1B,CD1D,SYK,HMGB1,SOX2,PPP3CA,YES1,TFRC,IL2RG,RPS3,NCK1,SELENOK,TESPA1,GPAM,TGFB2,CX3CL1,IL1A,SMAD3,XCL1,CALR,IL10,IGF1,ACTB,EP300,TNF,CD209,VSIR,MIR30B,MIR21,CD4,MIR519D,LILRB4,CD81,CXCL13,CD46,JUP,RELL2,ZBTB16,PRKCQ,IL4,JAK1,SMARCD3,EMP2,RUNX1,SOCS5,PIK3R2,F11R,IL7,IL23A,ADGRG1,CD80,CBFB,CD28,CD36,B2M,VEGFA,TFE3,ARPC2,WNT10B,SMARCB1,EPO,CAV1,IL15,CDK6,FLOT1,SMARCE1,THY1,KLHL25,CD40LG,LEP,BTN2A2,ST3GAL4,IL6ST,PTPN11,BCL10,HSPD1,LAMB2,DAG1,HTR2A,FOXP3,IL12A,SRC,CD274,DHPS,FUT1,LILRB1,ANGPT1,ITGAV,SASH3,ACTL6A,NKAP,PNP,IL18,CD83,CD86,CDC42,ROCK1,ITGA6,P2RY12,FERMT2,IL6,CSK,IL21,SFRP1,EPHA4,STK4,SLC7A1,IL12B,IFNG,ACTL6B,CCL5,PIK3CA,CD47,SDC4 |
| 1.690e-02 | -4.08 | CFDP1 (craniofacial development protein 1) | protein interactions | 10428 | 72 | 29 | 19454 | 5460 |
H2AC4,CSNK2A1,H2BC9,TOP1,EIF3K,ZNF330,H2AZ1,SMAD3,CALML5,H2BC1,H2BC11,CBX3,DMAP1,RPA2,LMNA,SART3,RBPJ,JUN,RUVBL1,KRAS,H3C1,COIL,RPA3,HADHA,NUP50,EP300,EWSR1,RUVBL2,HSPA8 |
| 1.690e-02 | -4.08 | ARPC5L (actin related protein 2/3 complex subunit 5 like) | protein interactions | 81873 | 72 | 29 | 19454 | 5460 |
ACTB,DAPK1,DYRK1A,ESR2,CDK9,GADD45G,SH3BGRL,CTTN,CALU,MYC,MOV10,ACTR3B,UFD1,XPO1,BTF3,HDAC6,HSPA5,ARPC2,STK26,RAB27A,TWNK,ARPC3,CAPZA2,ACTR2,EZH2,NUPR1,CFTR,ACTN4,SOX2 |
| 1.690e-02 | -4.08 | MZT2B (mitotic spindle organizing protein 2B) | protein interactions | 80097 | 72 | 29 | 19454 | 5460 |
KDELR2,NPY2R,HCST,TP53,CSNK1A1,DNAJC2,WWP1,MLC1,CXCR4,RUSF1,SLC5A6,SEMA4C,P2RY10,OPRM1,GPR17,CUL3,MYC,HSPA14,ICAM1,FBXW11,SNRNP70,TUBG1,SPINT2,SRPK2,APLNR,DUOXA2,TXNDC12,NRSN2,FZR1 |
| 1.690e-02 | -4.08 | TOR1A (torsin family 1 member A) | protein interactions | 1861 | 72 | 29 | 19454 | 5460 |
RPA3,DNAJC3,TMEM106B,HSCB,RER1,TOR2A,COPS4,CLU,TOR3A,TOR1AIP2,TMEM106A,SNAPIN,H2AX,LMNA,RPA2,RMDN3,SEC61B,HSD11B1,MGST3,TOR1B,VIRMA,MDFI,BTF3,FAM20B,GGH,SDF2L1,C1GALT1C1,CNIH4,BRD3 |
| 1.690e-02 | -4.08 | SDCBP2 (syndecan binding protein 2) | protein interactions | 27111 | 72 | 29 | 19454 | 5460 |
SEC23A,PAFAH1B3,HSBP1,TRAF1,NUF2,RPL22,AKAP17A,LYAR,DPPA2,ZCCHC10,MED4,CHCHD1,FAM83A,RAB9A,SREK1IP1,TIFA,NKAPD1,EIF1AD,AP1M1,ARF4,TM4SF1,ZNF581,TANK,PRR13,PHC1,THAP6,ZCCHC17,SDCBP,TCP11L1 |
| 1.690e-02 | -4.08 | GPC3 (glypican 3) | protein interactions | 2719 | 72 | 29 | 19454 | 5460 |
CLEC12B,GPIHBP1,CAMKV,LRRTM2,NT5C3A,NOG,HADHA,LRRTM3,NRN1,TRIM68,SIGLECL1,MOXD1,PIP5K1A,RAP1A,RAF1,TULP3,KCTD10,DNAJC1,VKORC1L1,FOLR1,CCNF,GNPAT,DNASE1L1,MUL1,TAFAZZIN,REEP6,EMC4,HMOX2,FGF1 |
| 1.690e-02 | -4.08 | HERC4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4) | protein interactions | 26091 | 72 | 29 | 19454 | 5460 |
UBE2L3,APEX1,USP5,NUF2,PGR,RB1,CCNF,ALYREF,DNAJC7,HSP90AA1,HERC4,SMAD4,LSM6,UBE2E3,H2AZ2,NT5C2,GMNN,BAG3,ERCC3,MOV10,DCTPP1,PCNA,NUBP2,RPA3,APOBEC3D,ISG15,MAP1LC3B,TPT1,HEXA |
| 1.690e-02 | -4.08 | RNASEH2A (ribonuclease H2 subunit A) | protein interactions | 10535 | 72 | 29 | 19454 | 5460 |
NUBP2,PCNA,RNASEH2C,UGDH,DDX39B,IMMP2L,POLDIP3,AP1M1,H3C1,SETD3,EDF1,H2AX,MAMDC2,FEN1,FAM136A,PSRC1,RPA2,DECR2,PRDX2,CUL3,MOV10,AGPAT1,HTRA2,UBE2H,KLHL1,FBXW11,BRCA1,FYTTD1,FAS |
| 1.691e-02 | -4.08 | bone-extraskeletal-chondrosarcoma-myxoid | COSMIC cancer mutations | bone-extraskeletal-chondrosarcoma-myxoid | 11 | 7 | 16828 | 4835 |
IDH1,TFG,PTEN,SMARCB1,EWSR1,SS18,TERT |
| 1.691e-02 | -4.08 | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_I | 11 | 7 | 16828 | 4835 |
GNAQ,PTPN11,IDH1,IDH2,GNA11,KRAS,TP53 |
| 1.691e-02 | -4.08 | stomach-carcinoma-tubular_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-tubular_adenocarcinoma | 11 | 7 | 16828 | 4835 |
MSH6,SF3B1,NTRK3,STK11,HRAS,KRAS,TP53 |
| 1.691e-02 | -4.08 | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma-spindle | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma-spindle | 11 | 7 | 16828 | 4835 |
PTEN,EWSR1,SUFU,PIK3CA,CTNNB1,KRAS,KIT |
| 1.691e-02 | -4.08 | pancreas-carcinoid-endocrine_tumour-non_functioning | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-non_functioning | 11 | 7 | 16828 | 4835 |
SMAD4,PTEN,CDKN2C,TP53,KRAS,CTNNB1,RB1 |
| 1.691e-02 | -4.08 | skin-hand-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-hand-malignant_melanoma-acral_lentiginous | 11 | 7 | 16828 | 4835 |
IDH2,IDH1,CTNNB1,MET,HRAS,KIT,BAP1 |
| 1.691e-02 | -4.08 | giant_cell_tumour | COSMIC cancer mutations | giant_cell_tumour | 11 | 7 | 16828 | 4835 |
HRAS,KIT,MET,CTNNB1,PTPN11,CDH11,EWSR1 |
| 1.691e-02 | -4.08 | tubular_adenocarcinoma | COSMIC cancer mutations | tubular_adenocarcinoma | 11 | 7 | 16828 | 4835 |
MSH6,HRAS,KRAS,TP53,SF3B1,NTRK3,STK11 |
| 1.691e-02 | -4.08 | skin-foot-malignant_melanoma-nodular | COSMIC cancer mutations | skin-foot-malignant_melanoma-nodular | 11 | 7 | 16828 | 4835 |
IDH1,IDH2,HRAS,KIT,KRAS,CTNNB1,PTEN |
| 1.691e-02 | -4.08 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-B_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-B_cell_lymphoma_unspecified | 11 | 7 | 16828 | 4835 |
JAK2,KRAS,HRAS,EZH2,MYD88,PTEN,CD79B |
| 1.691e-02 | -4.08 | endometrium-carcinoma-mixed_adenosquamous_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_adenosquamous_carcinoma | 11 | 7 | 16828 | 4835 |
PTEN,SF3B1,AKT1,HRAS,KIT,CTNNB1,KRAS |
| 1.691e-02 | -4.08 | radius | COSMIC cancer mutations | radius | 11 | 7 | 16828 | 4835 |
PIK3CA,CDH11,EWSR1,KRAS,TP53,IDH1,IDH2 |
| 1.691e-02 | -4.08 | seborrhoeic_keratosis | COSMIC cancer mutations | seborrhoeic_keratosis | 11 | 7 | 16828 | 4835 |
TERT,PIK3CA,HRAS,CTNNB1,PTPN11,AKT1,PTEN |
| 1.691e-02 | -4.08 | skin-back-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-back-malignant_melanoma-superficial_spreading | 11 | 7 | 16828 | 4835 |
GNAQ,STK11,PIK3CA,CTNNB1,KRAS,KIT,HRAS |
| 1.693e-02 | -4.08 | Legionellosis | KEGG pathways | ko05134 | 55 | 27 | 7161 | 2463 |
CD14,CXCL1,CLK1,IL12A,IL12B,NFKBIA,TLR4,IL18,CXCL8,SEC22B,RAB1A,EEF1G,ARF1,SAR1B,CXCL3,NFKB1,MYD88,TLR2,PYCARD,TNF,HSPD1,HSPA8,IL1B,RAB1B,EEF1A1,TLR5,IL6 |
| 1.693e-02 | -4.08 | Legionellosis | KEGG pathways | hsa05134 | 55 | 27 | 7161 | 2463 |
CXCL3,NFKB1,MYD88,ARF1,EEF1G,SAR1B,TNF,HSPD1,HSPA8,EEF1A1,RAB1B,IL1B,TLR5,IL6,TLR2,PYCARD,CXCL1,CLK1,CD14,IL18,TLR4,CXCL8,SEC22B,RAB1A,IL12B,IL12A,NFKBIA |
| 1.694e-02 | -4.08 | RNA polymerase II general transcription initiation factor binding | molecular function | GO:0001091 | 25 | 13 | 18094 | 5411 |
GTF2A1,NOP58,TAF7,ZNHIT6,AR,GTF2F1,RUVBL1,DRAP1,GTF2E2,EDF1,GTF2A2,RUVBL2,TP53 |
| 1.694e-02 | -4.08 | R-SMAD binding | molecular function | GO:0070412 | 25 | 13 | 18094 | 5411 |
JUN,PAX6,SMAD2,DDX5,SMAD3,PPARG,STUB1,DROSHA,LDLRAD4,SMAD4,RGCC,FOS,SMURF1 |
| 1.694e-02 | -4.08 | DHX29 (DExH-box helicase 29) | protein interactions | 54505 | 90 | 35 | 19454 | 5460 |
RPS9,IFIT2,METAP2,OPTN,CCNF,PSPC1,RPL10,APEX1,RPL7L1,RPS16,FZR1,RPS10,COPS5,WWP2,VAMP5,IFI16,MYC,CSK,UBE2H,POU5F1,NAPA,SNRNP70,HSPA8,RPA3,G3BP2,FTL,STAU1,RBMS2,OTUD6B,EDF1,PABPC5,TBC1D17,RPS11,DNAJC2,RPA2 |
| 1.694e-02 | -4.08 | RNF166 (ring finger protein 166) | protein interactions | 115992 | 90 | 35 | 19454 | 5460 |
UBE2E2,CUL3,USP2,XAF1,PLPP4,TNFAIP6,TNFAIP3,UBE2H,TRAF6,UBE2E3,UBE2D1,TNKS,PLPPR1,LIG3,BOLL,NUP35,ACP2,UBB,GMDS,SNX3,MATR3,FZR1,UBE2W,APOC2,PARP11,TFCP2,MAVS,SQSTM1,LTBR,RNF41,MAGEC2,TNKS2,UBE2K,NF2,UBE2D3 |
| 1.694e-02 | -4.08 | CST4 (cystatin S) | protein interactions | 1472 | 90 | 35 | 19454 | 5460 |
FTH1,TIMM10,CHST7,E2F6,RHOBTB1,FKBP14,HBM,HINT2,HSPA8,RING1,NPB,UCP2,DCTN3,SNAPC1,SLC25A10,MTHFD2L,TCF23,GREM2,POLL,STK11,TTL,TADA3,NXT1,CORO1C,CHAC2,GTF2B,TMEM176B,SCAMP2,RNF208,UQCRQ,UBTD2,RNF141,NKAP,B3GALNT1,PRKCE |
| 1.694e-02 | -4.08 | MED25 (mediator complex subunit 25) | protein interactions | 81857 | 90 | 35 | 19454 | 5460 |
MED30,SMAD1,MED9,ODAM,KLHL12,MED31,HGS,CDK8,MED23,TRIP4,FAM168B,TFG,PTGES3,LASP1,MED11,PRDX1,CREBBP,H2AC14,WWP2,MED22,SERTAD3,SMAD2,NCKIPSD,MED4,RIT1,MED27,MED21,MED10,MED29,STN1,POLR2F,FEZ1,RORB,ESR2,MED17 |
| 1.694e-02 | -4.08 | PRTN3 (proteinase 3) | protein interactions | 5657 | 90 | 35 | 19454 | 5460 |
EGFL8,BIRC2,SEC11A,ITGA2,SPCS2,HSPA5,IL1B,TNF,TUBA1A,TMEM59,CCDC47,ITGB5,CCR1,SERPINA1,CTBP1,PRSS8,DCK,SMAD3,HDHD5,EGLN3,KLK3,ESR2,NLGN2,SPCS1,TUBB,RNF40,LYPLAL1,KLHL22,DHPS,ISX,STK11,SERPINB1,AGPAT1,CAMP,CYP3A43 |
| 1.697e-02 | -4.08 | human chr20q11.21 | chromosome location | human chr20q11.21 | 53 | 19 | 26134 | 5823 |
BPIFB1,FOXS1,DEFB115,SNTA1,DEFB124,DEFB121,BPIFB3,BPIFA2,HM13,KIF3B,BPIFA3,PDRG1,COX4I2,BPIFB4,ID1,MAPRE1,BCL2L1,DEFB116,TM9SF4 |
| 1.698e-02 | -4.08 | CRP (C-reactive protein) | protein interactions | 1401 | 75 | 30 | 19454 | 5460 |
BPNT2,SNRNP70,PDF,ST3GAL4,FCGR1A,RPL23,AGPAT1,H1-1,GMPPA,CNTNAP1,FCGR2B,FCGR2A,B4GALT4,RPL13A,LRRC24,B4GALT3,HS3ST1,EXT1,PRSS23,RPL26L1,LEP,STRBP,ESS2,TMEM59,LAMB2,B4GALT7,HSPA5,TIMP3,UBE3A,NXPE3 |
| 1.698e-02 | -4.08 | RDH13 (retinol dehydrogenase 13) | protein interactions | 112724 | 75 | 30 | 19454 | 5460 |
NRP1,PSKH1,SAMHD1,EMILIN1,KDSR,TMEM208,PCDHB1,GADD45G,SLC25A12,ESR2,RAB1B,LSM5,COPZ2,BRD9,AMIGO1,OPTN,GNAI3,RPN1,CYP3A5,CCM2,CFTR,TP53,PDE2A,LYG2,SLC15A1,ETFA,NMRAL1,RAB1A,NDUFA4,IDH3A |
| 1.698e-02 | -4.08 | XPNPEP3 (X-prolyl aminopeptidase 3) | protein interactions | 63929 | 75 | 30 | 19454 | 5460 |
SPOP,CUL3,RELL1,AUH,CSK,BAG3,HNRNPL,IDE,CHGA,TNFRSF1B,ALYREF,FOLR1,MRPL53,LDLR,CHMP4C,FGFR1,PAK5,DYRK2,TP53,CFAP418,CFTR,SOX2,MRPL57,HNRNPK,CHCHD2,POLDIP2,HNRNPA2B1,MAIP1,BAP1,DPH6 |
| 1.698e-02 | -4.08 | GZF1 (GDNF inducible zinc finger protein 1) | protein interactions | 64412 | 75 | 30 | 19454 | 5460 |
DDX39A,RPSA,RAF1,RPL27A,RPLP0,RNF113A,RPL3,RPL23A,PPAN,RPL17,RPL28,SRSF4,RPL4,H1-6,DGCR8,E4F1,RPL26,RPL6,RPL7A,RPL10A,CRBN,PRKRA,KRR1,RPL8,RPS3,ESR2,RPL19,SURF6,RPL7,RPL13A |
| 1.698e-02 | -4.08 | CYRIB (CYFIP related Rac1 interactor B) | protein interactions | 51571 | 75 | 30 | 19454 | 5460 |
TFDP2,NIF3L1,AGR2,OSGEP,DNAJB6,CABCOCO1,CYRIA,MTPN,THAP8,RPL35A,DERL2,PRELID1,FAM118B,WIF1,MTAP,RPA2,CHMP4C,PPME1,PAQR3,TIMMDC1,CENPM,PPIL3,GTF2E2,GPM6A,FGF12,RIGI,RGS2,RPA3,HSPA8,IDH1 |
| 1.699e-02 | -4.07 | VTA1 (vesicle trafficking 1) | protein interactions | 51534 | 133 | 49 | 19454 | 5460 |
RPA3,BAP1,XRCC5,RABAC1,FLCN,PSMA3,NF2,SMC4,CHMP2B,PSMC1,PSMC4,ATP6V1C1,VPS4B,RPA2,CHMP1A,ACACA,CNDP2,CCNF,CTTN,PRMT5,SNRPD2,GSK3A,PSMC5,ADRM1,CHMP5,PSMB6,MYC,PSMD1,BEX3,IVNS1ABP,CHMP1B,ZBTB16,TOLLIP,RPIA,XPNPEP1,MCM6,PHF23,CDK4,PPP2R1A,KLHL12,PSMC3,FBXO32,DPPA2,CGAS,DERL2,MYL12A,CHMP2A,PSMD3,VPS4A |
| 1.700e-02 | -4.07 | CFAP20 (cilia and flagella associated protein 20) | protein interactions | 29105 | 87 | 34 | 19454 | 5460 |
RSRC1,OPTN,FAM149B1,MRPS28,SPINDOC,SNRPD3,ADCK1,ESR2,MRPS35,YWHAG,XPO1,SNRNP70,ARL2BP,UBE2H,DICER1,RIT1,SNIP1,RPA3,YAF2,RNF113A,CDK20,UFL1,PDHB,KRAS,RAF1,ATG16L1,CFTR,CHMP4C,EZH2,RPA2,SART3,NUPR1,DYRK2,ZRANB2 |
| 1.700e-02 | -4.07 | GTF2IRD1 (GTF2I repeat domain containing 1) | protein interactions | 9569 | 87 | 34 | 19454 | 5460 |
TOP3B,ISG15,ZMYM3,SDC2,ZC4H2,CBX3,PIP4P2,ATP2C1,MRFAP1L1,SPOPL,TMEM168,EXOSC4,HDAC3,CDK20,KPNA2,PIAS1,WASF3,SELENOS,FGF1,GORASP2,FBXW11,BRCA1,LGALS8,SP1,KPNA1,SMAD2,HNRNPD,SYNCRIP,SMAD3,ZMYM2,INTS12,HNRNPL,AASDHPPT,CBX5 |
| 1.700e-02 | -4.07 | CSTF2T (cleavage stimulation factor subunit 2 tau variant) | protein interactions | 23283 | 87 | 34 | 19454 | 5460 |
XPO1,RUNX1,CPEB1,CPSF2,PAPOLA,AKAP8L,CRTAP,FBXW11,RFX5,ANAPC2,CPSF1,CSTF3,VIRMA,SMYD3,ATG16L1,CPSF4,TIMMDC1,CAPN2,HGS,RPA2,P3H1,CTDSP1,FEM1A,EWSR1,BIRC2,SQSTM1,BAG2,AKAP1,RPA3,FAM168B,CDSN,FANCG,KDM1A,LASP1 |
| 1.703e-02 | -4.07 | Glutamate Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-210500 | 24 | 13 | 10285 | 3229 |
STX1A,STXBP1,PPFIA3,RAB3A,SNAP25,PPFIA2,CPLX1,VAMP2,SLC1A1,SLC1A2,ARL6IP5,SLC38A2,SLC1A3 |
| 1.704e-02 | -4.07 | TNFSF14 (TNF superfamily member 14) | protein interactions | 8740 | 78 | 31 | 19454 | 5460 |
SYS1,GP9,EIF2B3,TM9SF1,COQ8B,TRAF2,SEC22A,KDELR2,RUVBL1,ADIPOQ,YTHDF1,HSPA5,TMEM209,HS2ST1,RUSF1,LTBR,JAGN1,RUVBL2,BIRC2,TMEM11,HAX1,TMEM30A,TNFRSF14,NUDT1,CLDN11,TAMM41,LTB,DNAJB9,EIF2B5,CXCL9,SEC23A |
| 1.704e-02 | -4.07 | GINS4 (GINS complex subunit 4) | protein interactions | 84296 | 78 | 31 | 19454 | 5460 |
ATXN10,METAP2,MRPL13,IGBP1,YWHAZ,EIF5A2,RIT1,PTTG1,LDHB,MCM3,CTNNBIP1,MCM4,FBXW7,KRAS,PPP1R2,AHCYL1,SSRP1,MCM6,GINS3,NCDN,RPA3,MRPS11,PDHA1,DMAP1,MED23,RPA2,PPIL3,GTF2E2,CD2BP2,PPP2R1A,H2AX |
| 1.704e-02 | -4.07 | APBB2 (amyloid beta precursor protein binding family B member 2) | protein interactions | 323 | 78 | 31 | 19454 | 5460 |
NCK1,SMAD4,LAMTOR1,NRP1,RAB11A,NFKB1,ATG9A,HNRNPL,VIRMA,CAV1,SMURF1,STX6,RAB35,SYNCRIP,SEC61B,GJA1,SFTPC,FGFR1,LDHAL6B,TBC1D4,TP53,ATG16L1,OTULINL,TUBA1A,RAB3B,STX7,TMT1A,RAB5A,AKAP1,RAB9A,HSPA8 |
| 1.704e-02 | -4.07 | ELP2 (elongator acetyltransferase complex subunit 2) | protein interactions | 55250 | 84 | 33 | 19454 | 5460 |
FAM219B,CCNF,KTI12,COX4I1,EGLN3,DYRK1A,SNRPB2,JAK2,STAT1,MATR3,MPG,HMGA1,MOV10,CIAO1,TAF9,UBE2H,RIT1,ELP6,SMAD4,JAK1,EP300,NUBP2,DUSP9,RPA3,RIGI,FTL,KRAS,CD2AP,ELP3,PAAF1,TP53,POLR2D,RPA2 |
| 1.704e-02 | -4.07 | ATP6V1G1 (ATPase H+ transporting V1 subunit G1) | protein interactions | 9550 | 84 | 33 | 19454 | 5460 |
GORASP2,NTAQ1,ROGDI,RAB11A,RIT1,ATP6V1D,CBL,SLC35A1,ATP6V1A,CYB5A,TLDC2,VPS72,PNMA1,ATP6AP2,ZNF511,UBE2V1,ATP6V1E2,MTA3,RAF1,ATP6V1C1,LACC1,PTP4A2,PMAIP1,SRSF7,HSPA8,CTTNBP2,TBC1D24,RIGI,SNRPG,CMAS,LDOC1,ATP6V1G2,KRAS |
| 1.705e-02 | -4.07 | ATP11C (ATPase phospholipid transporting 11C) | protein interactions | 286410 | 81 | 32 | 19454 | 5460 |
CLRN2,VIRMA,OSBP,POPDC2,VAMP3,SCN2B,SLC6A1,TMEM30A,UPK1A,P2RY1,SLC2A1,LACRT,MBLAC2,BTF3,TMEM107,LAMP3,SCGB1D1,RAB2A,LAMP2,CSK,AZGP1,GCNT3,TAS1R2,PMAIP1,TMEM185A,LCN1,STX12,JCHAIN,SEMA7A,RPA2,NRN1,MARCKSL1 |
| 1.705e-02 | -4.07 | THRB (thyroid hormone receptor beta) | protein interactions | 7068 | 81 | 32 | 19454 | 5460 |
ZNHIT3,MED21,KPNA1,MPG,NR2F6,BTF3,ACTB,HNRNPL,SRC,LRIF1,ACTA2,LIG3,RXRG,UBE2I,COPS2,LDLR,TSG101,PSMC5,ACVR1,BTG1,CCND1,TP53,ANP32A,DDX39A,MECR,PRMT2,HDAC3,EIF5B,NRBF2,XRCC5,TRIP4,C1D |
| 1.705e-02 | -4.07 | PPP2R5C (protein phosphatase 2 regulatory subunit B'gamma) | protein interactions | 5527 | 81 | 32 | 19454 | 5460 |
UGP2,RIGI,PTGES3,HAPSTR1,EP300,RPA3,FAF1,HNRNPA2B1,PPP4C,RPA2,PPP2R1A,PPP1CB,SOX2,TP53,MDM2,FAM43A,PPP2R5E,BAD,PPP2CB,IER3,SWAP70,YWHAB,UBE2H,PSMG3,YWHAZ,LSM6,BRCA1,PPIL4,API5,PPP1CC,PPP2R5A,CUL3 |
| 1.705e-02 | -4.07 | PRCC (proline rich mitotic checkpoint control factor) | protein interactions | 5546 | 81 | 32 | 19454 | 5460 |
SNRNP40,MAD2L2,ESR2,CDC5L,HOMER3,CHORDC1,YWHAZ,DNAJC10,PIM2,DRG1,PRPF19,SUB1,XPO1,CSNK2A1,GORASP2,LSM4,SRSF2,SCYL2,RPA3,FAF1,SOD1,PML,SEPTIN7,EWSR1,CDK5,EP300,NUP50,RPA2,CBX3,LSM2,SH3GLB1,PCK2 |
| 1.710e-02 | -4.07 | thyroid-carcinoma-papillary_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-papillary_carcinoma | 112 | 43 | 16828 | 4835 |
METTL14,PTEN,TPM3,AKT2,FGFR1,TERT,ASPM,CDK4,GABRA2,ETV6,JAK2,FBXW7,MET,KIT,TIRAP,TFG,TP53,SMAD4,GOLGA5,IDH1,KRAS,SMARCB1,DICER1,EZH2,PIK3CA,PTPN11,AKT1,IDH2,RB1,GNA11,TRIM24,CTNNB1,TSHR,CHGA,SF3B1,STK11,GNAQ,MAP2K1,TRIM27,PIK3R1,HRAS,AKT3,MRPL50 |
| 1.710e-02 | -4.07 | papillary_carcinoma | COSMIC cancer mutations | papillary_carcinoma | 112 | 43 | 16828 | 4835 |
KRAS,IDH1,SMAD4,GOLGA5,TFG,TIRAP,TP53,KIT,MET,FBXW7,JAK2,ETV6,TERT,ASPM,CDK4,GABRA2,FGFR1,TPM3,AKT2,METTL14,PTEN,MRPL50,AKT3,HRAS,PIK3R1,TRIM27,MAP2K1,STK11,GNAQ,SF3B1,TSHR,CHGA,TRIM24,RB1,GNA11,CTNNB1,IDH2,PTPN11,AKT1,PIK3CA,DICER1,EZH2,SMARCB1 |
| 1.714e-02 | -4.07 | proton transmembrane transport | biological process | GO:1902600 | 136 | 52 | 18204 | 5365 |
ATP6V1G1,SLC15A1,ATP6AP2,ATP6V1C1,SLC25A3,ATP5F1A,GHITM,RNASEK,SLC4A10,ATP5MC3,ATP6V1D,UQCRH,COX4I2,ATP6V0E1,ATP5MG,ATP6V1G2,CYB5A,COX7B,UCP2,ATP6V0B,SLC18B1,ATP5PB,COX6B1,UQCRC1,ATP5PD,SLC25A4,ATP5F1B,ATP1A1,ATP5PF,SLC25A12,ATP6V1E2,ATP1A2,SLC25A14,COX7A1,SLC16A1,ATP1A3,ATP5PO,ATP1B1,SLC15A2,COX4I1,SLC25A27,CYC1,SLC17A5,COX5A,SLC11A2,ATP6V1A,ATP5F1E,SLC25A5,ATP5F1D,ATP5MC1,SLC32A1,COX8A |
| 1.717e-02 | -4.06 | TNS4 (tensin 4) | protein interactions | 84951 | 43 | 19 | 19454 | 5460 |
GAB1,CRYBB3,P4HA2,TRIM21,TRIM27,GPX1,NME4,GSTCD,UBXN6,PIK3R1,SFN,SOX2,AR,RPAIN,MET,CBL,PIH1D1,PPP3CA,ZER1 |
| 1.717e-02 | -4.06 | TSR3 (TSR3 ribosome maturation factor) | protein interactions | 115939 | 43 | 19 | 19454 | 5460 |
P4HA2,RNF34,RAP2A,EP300,MEF2A,FTL,RPL10,GFOD1,ATG4A,TOP3B,CCND1,PSMC3,MAF1,RNF181,BRD3,KCTD12,FOSL2,OSER1,RHOB |
| 1.717e-02 | -4.06 | FOSB (FosB proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 2354 | 43 | 19 | 19454 | 5460 |
FOS,FAM222B,EP300,FOXP3,TSR3,ENKD1,JUNB,RIGI,PCGF6,APEX1,PHF1,CYTH4,AUH,CREBBP,BAG3,JUN,NFE2L2,TRIB1,COP1 |
| 1.717e-02 | -4.06 | RNF14 (ring finger protein 14) | protein interactions | 9604 | 43 | 19 | 19454 | 5460 |
RBBP4,UBE2D3,IMMP2L,UBE2L3,UBE2E2,CUL3,UBE2W,VDR,RNF14,AKT1,TNFAIP3,CTNNB1,UBE2V1,DET1,AR,HNRNPA1,UBE2E3,UBE2D1,PHF7 |
| 1.717e-02 | -4.06 | TSSK6 (testis specific serine kinase 6) | protein interactions | 83983 | 43 | 19 | 19454 | 5460 |
TMEM160,AIP,CCT8,LSM14A,HSPA8,CLPB,H3C1,TCP1,THRAP3,POLR2B,MDM2,HSP90AB1,CCT7,CCT5,H2AX,CCT2,LARP4B,HSP90AA1,HAX1 |
| 1.717e-02 | -4.06 | UAP1 (UDP-N-acetylglucosamine pyrophosphorylase 1) | protein interactions | 6675 | 43 | 19 | 19454 | 5460 |
FBXO32,PABPC1,SDHB,RPA3,CCNF,YWHAZ,AGR2,UAP1,RPA2,YWHAB,HSPB1,BRD3,HNRNPD,TPT1,SFN,NFYA,VPS39,YWHAG,YWHAH |
| 1.717e-02 | -4.06 | PDCD2 (programmed cell death 2) | protein interactions | 5134 | 43 | 19 | 19454 | 5460 |
EGLN3,LSM8,ZBTB2,PTGES3,SRC,CAMKV,RPS16,SPPL3,EP300,PSPC1,NFKBIB,RPS2,CERK,FAS,CD59,ERRFI1,MYC,CUL3,IL1R2 |
| 1.717e-02 | -4.06 | TMEM177 (transmembrane protein 177) | protein interactions | 80775 | 43 | 19 | 19454 | 5460 |
MRPL24,KRAS,PNP,MRPL50,OXCT1,MRPL52,SYNCRIP,HSPD1,CCNF,NDUFA4,MRPL51,MRPL49,SLC25A3,AQP3,MRPL9,MRPL16,CDK7,RRM1,MRPL11 |
| 1.717e-02 | -4.06 | SSNA1 (SS nuclear autoantigen 1) | protein interactions | 8636 | 43 | 19 | 19454 | 5460 |
PICK1,PSMC5,LCA5,PLAC9,CDR2L,SSNA1,SRI,CARTPT,NTAQ1,SPATA2,TIMM10,NUP62,TANK,EHHADH,MED4,SDCBP,CTBP1,CHCHD4,MED29 |
| 1.720e-02 | -4.06 | IFN-gamma pathway | Pathway Interaction DB | ifngpathway | 40 | 21 | 2226 | 782 |
STAT1,MAP2K1,DAPK1,PIK3R1,JAK1,JAK2,PTPN11,PIK3CA,IRF9,EP300,CAMK2G,PIAS1,CRKL,AKT1,CBL,CREBBP,MAP3K11,IFNG,IRF1,IL1B,IFNGR1 |
| 1.722e-02 | -4.06 | PAZ | prosite domains | PS50821 | 9 | 6 | 12186 | 3388 |
PIWIL3,PIWIL4,PIWIL2,DICER1,AGO1,PIWIL1 |
| 1.722e-02 | -4.06 | ZF_RING_1 | prosite domains | PS00518 | 166 | 59 | 12186 | 3388 |
TRIM3,TRIM6,TRIM52,TRIM21,RNF146,TRAF2,COP1,TRAF6,TRIM27,TRIM8,TRIM68,TRIM54,TRIM32,TRIM36,PCGF3,RNF5,PCGF6,RNF182,RNF39,RNF222,RING1,RAG1,CBLL1,RNF187,TRIM15,BFAR,TRIM35,TRIM11,SHPRH,RNF20,RNF8,TRIM23,TRIM45,TRIM46,TRIM22,RNF141,RC3H2,TRIM63,RNF113A,CBL,RNF41,TRIM62,PCGF2,RNF144B,RNF40,MNAT1,TRIM34,TRIM24,PML,TRIM5,TRAF7,RNF208,RNF14,LNX2,RNF10,RBCK1,TOPORS,TRIM10,BRCA1 |
| 1.726e-02 | -4.06 | maintenance of protein location | biological process | GO:0045185 | 89 | 36 | 18204 | 5365 |
YWHAB,SRGN,HSPA5,TSPO,PGR,CDK5,SUFU,AKT1,SKP1,PDIA2,TOPORS,INSIG2,CER1,FKRP,CD4,CCDC22,RER1,G3BP2,CAV1,NFKBIA,PSMD10,IL10,MDFI,GPAA1,RIT2,OS9,ARL2BP,TMSB4X,PML,TMSB10,TXN,KDELR1,FAF1,KDELR2,SUPT7L,IGSF11 |
| 1.727e-02 | -4.06 | WEE1 (WEE1 G2 checkpoint kinase) | protein interactions | 7465 | 130 | 48 | 19454 | 5460 |
VIRMA,SMURF1,CSNK2B,CCNF,RIT1,CDC73,HSP90AA1,YWHAZ,FBXW11,BRCA1,MCM4,RUSC2,SFN,CCNB1,MYC,AKT1,CDC16,FBXW7,EP300,ATP5F1E,CSNK1A1,ACACA,CDK1,SPTBN1,TOP1,FZR1,KCTD3,INA,CDCA3,RB1,H2AZ1,SMAD3,YWHAB,USP15,CDKN1B,CDK12,SMAD4,XPO1,CSNK2A1,YWHAG,YWHAH,POGK,PIK3R1,KRAS,EEF2,TUBA1A,IPO8,ERRFI1 |
| 1.727e-02 | -4.06 | cellular response to tumor necrosis factor | biological process | GO:0071356 | 157 | 59 | 18204 | 5365 |
TRAF1,TRAF3IP2,CRHBP,TXNDC17,HYAL2,TRAF2,SFRP1,CTSK,CX3CR1,CAMP,MIR34A,BIRC2,ZFAND6,RPS3,IL18BP,EDA2R,NFKBIA,FOXP1,TNF,CCL5,CXCL8,RRAGA,AKAP12,TP53,NKX3-1,CD58,PYCARD,TNFSF18,TANK,KCNJ11,CCL3,AKT1,INPP5K,DHX9,CD40,ILK,NFKB1,KRT8,TNFRSF14,JAK2,NFE2L2,FOS,CHI3L1,CCL2,TMSB4X,STAT1,IKBKB,ACTN4,CLDN1,TIFA,FABP4,PCK2,TNFRSF1B,FAS,TRAF6,BRCA1,CYP1B1,MIR31,PID1 |
| 1.728e-02 | -4.06 | learning | biological process | GO:0007612 | 154 | 58 | 18204 | 5365 |
DLG4,PAK5,SNAP25,DRD3,ARF4,NEUROD2,NOG,C1QL1,NETO1,CDK5,VDAC1,DKK1,HTR2A,COMT,SLC6A1,ELAVL4,YTHDF1,ATXN1L,PPP1R1B,EIF4A3,ASIC1,DBH,SLC1A1,UBE3A,PPT1,PAK6,SLC7A11,CHST10,KRAS,PTN,ATP1A2,PIAS1,NTRK2,OPRK1,TACO1,KIT,TNR,TACR1,TLR2,BTG2,PLCB1,CHRNB2,TUBA1A,FGF13,OPRL1,DRD1,RAG1,UCN,MECP2,JPH4,ATAD1,TPBG,FOS,ADCY3,SLC6A4,PDE1B,ATP8A1,CLN8 |
| 1.729e-02 | -4.06 | HSPA2 (heat shock protein family A (Hsp70) member 2) | protein interactions | 3306 | 404 | 133 | 19454 | 5460 |
KRT8,MAP1LC3A,RFX5,CBFB,DHX15,SNX1,HNRNPA1,GSTM3,CBL,PPM1B,AGR2,SLC25A23,UBE3A,BAG2,DNAJB4,EWSR1,SCYL2,PPWD1,CDK20,WDR37,LGR4,SNX20,HGS,GNB1L,METTL21A,SKA3,PARP2,LMBR1L,GNB1,TUBB,TCAP,MLF2,BAG3,CUL3,PAPOLA,PRMT6,MYC,DNAJB6,ILK,HSP90AA1,COP1,PELI3,PSMA3,HSPA8,FLYWCH2,FBXL4,CDKN1A,FUNDC1,TASL,TANK,ALKBH3,MTMR6,KLC2,PPT1,ADNP,PAK2,FOXS1,ARMC1,EEF1AKMT3,CDC5L,CDK9,MAPRE2,KCTD3,FZR1,LRRC40,HDAC6,DNAJB2,DNAJC7,GK5,CRBN,CLPB,SLC25A10,FAF1,PPP1R12A,FKBP8,FBXO25,MEPCE,BLOC1S3,ESS2,EEF1A1,TP53,UBL4A,PHC1,SLC25A20,KLHL26,TFCP2,CFAP298,PTEN,SRP54,PPM1M,QSER1,ACOX1,CCNF,TSSK1B,STUB1,VIRMA,CSTF3,CTTNBP2NL,GABPA,ADRM1,DHRS13,MAP3K3,DNAJC5,TUFM,PPP1CC,USP14,GMNN,ST13,ATP5F1A,RUNX1,RETSAT,MAT2A,CDC73,MAVS,NR1I3,RNF34,HMCES,SIRT7,MGAT4B,BAP1,GRPEL1,GTF2I,CFTR,CCND1,CAPN1,SF3A1,HAUS2,RARS1,HEXIM1,OXSR1,METTL14,FGFR1,CDK1 |
| 1.730e-02 | -4.06 | RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | REACTOME pathways | R-HSA-168928 | 84 | 36 | 10285 | 3229 |
NFKB1,TAX1BP1,AGER,IFNA2,IRF7,TANK,DHX9,UBE2K,NFKBIB,IFNA13,IRF3,IFNA10,ISG15,IRF2,CREBBP,S100B,TNFAIP3,TRAF2,UBE2D3,UBA52,RPS27A,UBB,MAVS,SIKE1,IKBKB,IRF1,UBE2D1,IFIH1,HMGB1,TRAF6,RIGI,EP300,NFKBIA,TBK1,IFNB1,MYD88 |
| 1.731e-02 | -4.06 | ion channel inhibitor activity | molecular function | GO:0008200 | 38 | 18 | 18094 | 5411 |
VAMP8,STX7,PACSIN3,PCSK9,CFTR,LAMP2,CAV3,LYNX1,STX1A,VTI1B,SCN3B,STX8,CAV1,FKBP1B,FKBP1A,KCNMB2,STOM,SCN1B |
| 1.737e-02 | -4.05 | TNF_dom | interpro domains | IPR006052 | 18 | 10 | 18521 | 5414 |
LTA,TNFSF8,LTB,TNF,TNFSF12,TNFSF15,CD40LG,TNFSF10,TNFSF13,FASLG |
| 1.741e-02 | -4.05 | WDR83 (WD repeat domain 83) | protein interactions | 84292 | 193 | 68 | 19454 | 5460 |
SPATA6,SRSF8,BAG2,ZC3H7A,CCT8,SNRPG,KRAS,CDC40,TSSC4,DDX39A,AURKAIP1,CCT5,TP53,UBL5,RAF1,SNRPE,VAC14,ZHX1,EIF4E2,CDC5L,CCT7,CEP19,CRB3,EGLN3,SNRPD3,BUD31,TCP1,KCTD3,ZCCHC10,PRPF19,RIMS4,HSPB1,SSX2IP,LSM3,KIAA1143,ECD,PSMG2,DDX23,HNRNPH2,NKAPD1,LCA5,BCL6,RP2,STAU1,KDM1A,CFTR,SIPA1L1,SNRPN,ATG16L1,SAP30BP,HECTD1,PARD6A,MAP2K1,FRS3,RNF187,SF3B4,CEP97,UBB,SNRNP40,TAB1,RPGRIP1L,LAMTOR3,KCTD9,RBM15B,RIT1,UBE2H,EXOSC1,CCT2 |
| 1.749e-02 | -4.05 | Peptide ligand-binding receptors | REACTOME pathways | R-HSA-375276 | 188 | 73 | 10285 | 3229 |
CCL27,CXCL8,F2,CXCL13,PPY,HCRT,CXCR3,RXFP2,CCR3,XCL1,RLN3,AVPR1B,CX3CL1,RLN2,CX3CR1,NPBWR1,CXCL11,SST,PROK1,CCL28,BRS3,OPRK1,CCL20,TACR1,MCHR2,CCR1,APLNR,CXCL1,TAC1,CCL21,NPY2R,CCL5,CXCR4,NPB,UTS2,CCL19,NMBR,NPSR1,NPW,TACR3,GPR37L1,PNOC,OPRM1,GHRL,GPR37,CCL25,UTS2R,MLN,CXCR1,EDNRA,CXCL12,CXCL9,NPY,CXCL10,PDYN,CCL23,OXTR,ACKR3,MCHR1,CCR4,OPRL1,CXCL3,HEBP1,CCR2,CXCR6,CCR6,NPY5R,APLN,CCR7,CCR5,CCL1,NPY1R,GRPR |
| 1.750e-02 | -4.05 | Alzheimers Disease | WikiPathways | WP2059 | 148 | 66 | 5310 | 1910 |
MIR29A,PLCB2,FAS,NAE1,MIR218-2,CAPN2,MIR769,APH1A,IL1B,MIR10A,BAD,MIR132,PPP3R2,MIR33B,CAPN1,MIR3200,MIR488,MIR873,MIR182,MIR139,MIR136,CDK5R1,MME,MIR9-1,MIR760,GNAQ,MIR218-1,MIR377,MIR9-3,MIR671,HSD17B10,MIR95,MIR598,CDK5,MIR495,MIR21,MIR375,TNF,MIR184,PLCB1,CHPF2,ATP5MK,MIR9-2,CHP1,IDE,MIR887,CALML5,MIR101-1,MIR129-2,VMP1,PSEN1,MIR874,MIR34B,GAPDH,CASP12,MIR34C,MIR129-1,PSENEN,PPP3CA,MIR181D,NCSTN,MIR708,TP53,BACE1,PSEN2,MIR125A |
| 1.750e-02 | -4.05 | hydrolase activity, acting on acid anhydrides | molecular function | GO:0016817 | 798 | 266 | 18094 | 5411 |
RASL12,RAB5A,HSP90B1,ARL5B,RAC2,RAB39B,DHX38,RHOJ,RAB29,PSMC4,NKIRAS2,ARL10,RHOG,RHOH,ARHGAP5,G3BP1,RAB9B,TRIM23,RFC4,DHX16,RALA,GNAO1,TCP1,ACTB,ABCE1,RAB19,GNB3,RAP2A,RGS10,RAB33B,ADPRM,HRAS,GNG11,MTG2,ATP6V1G1,ARF1,NTPCR,HSPD1,KIF2A,RGS5,ATP2B4,XRCC5,RAB35,MCM4,GNG5,RAB1A,KIF1C,RAB18,RAB3D,NUDT3,NUDT4,ATP1A1,ABCC5,GFM2,RGS6,TOR1B,HSP90AA1,AGAP1,PSMC1,GNGT2,GNAQ,ERAS,CDC42,ARL4A,RAP1A,RIT1,DRG2,SMARCA5,APTX,NUDT7,DHX15,MORC2,CLPX,RGS1,CCT8,DCTPP1,GNAI3,DRG1,EEF2,TWNK,ATP1A2,NUDT16,EIF5B,RAP1B,DCP2,ATP5F1A,ARL11,COQ8B,RRAGB,RAB3B,ATP6V1G2,RAB9A,MRAS,DDX42,GNAI2,ARF4,PSMC3,RAB1B,RAB5C,RAN,EIF4A2,NUDT9,RAB14,RAB27A,RAB28,ABCF1,MFN1,TOR3A,MCM6,RAB6B,TPPP,GTPBP2,RASL10A,PLPP4,RUVBL2,RFC2,RND3,DDX4,IFIH1,MX2,RUVBL1,GNB1,NUDT19,NUDT5,MX1,GNA11,IFT22,KATNAL1,RFC3,RALB,FHIT,ATP2C1,MTG1,ATP1A3,NLRP3,MOV10,RAP2C,SAR1B,MMUT,ERCC3,HSPA5,MORC4,ATAD1,GPN2,ALPL,DDX50,SHOC1,DIRAS2,RAB13,RABL2B,RHOB,RAB22A,RGS2,RND2,DDX23,RHOBTB3,GNG10,ABCG2,GFM1,SLC25A42,HSPA8,RAB32,RAB3A,MMAA,GNL1,GNAZ,CCT7,GNA14,RHEB,ATP5F1B,SEPTIN7,RAB30,TUBB4B,RASD1,ATP6V1A,CLU,CFTR,RAB4A,NUDT12,RAB11B,PLPP6,TUBB,DDX39A,SMC4,DDX39B,NUDT2,MLH3,MCM8,AGAP2,DIRAS1,DDX1,BCS1L,RERG,DNM2,RAB23,KIF3B,ARF6,DHX9,THTPA,RAB6A,EIF4A3,ATP8A1,DNAJC27,RASL10B,CLPB,ARL15,ENPP4,KIF3C,RAP2B,ENTPD4,RABL3,GTPBP1,PSMC5,KRAS,VPS4B,SRP54,GNG3,RIGI,RIT2,ABCB9,CCT5,ENTPD3,EEF1A1,SMCHD1,RFC5,ABCB1,RHOBTB1,ARL4D,ARL6,SEPTIN6,RAB37,DIRAS3,NUDT1,RAB31,MCM3,DDX5,HSPA13,RHOU,RGS19,TOR2A,RRAS2,NKIRAS1,NLRP1,TUFM,NUDT18,RAB11A,OLA1,VPS4A,RAB3C,HSP90AB1,FITM2,RRAGA,ABCC2,RAB40AL,RAB2A,CCT2,HSPA14,TOR4A,SRPRA,DXO,DDX46,RAB8B,ATL1,RASL11A,TUBA1B,RAB33A |
| 1.750e-02 | -4.05 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular function | GO:0016818 | 798 | 266 | 18094 | 5411 |
RRAS2,TOR2A,RGS19,DDX5,HSPA13,RHOU,RAB11A,NUDT18,VPS4A,RAB3C,OLA1,TUFM,NKIRAS1,NLRP1,CCT2,RAB40AL,RAB2A,HSPA14,HSP90AB1,FITM2,ABCC2,RRAGA,RAB8B,TUBA1B,RAB33A,RASL11A,ATL1,TOR4A,DXO,DDX46,SRPRA,RASL10B,EIF4A3,ATP8A1,DNAJC27,CLPB,ARL15,THTPA,ARF6,DHX9,RAB6A,PSMC5,GTPBP1,KRAS,VPS4B,KIF3C,RAP2B,ENPP4,ENTPD4,RABL3,ABCB1,RFC5,ARL4D,ARL6,SEPTIN6,RHOBTB1,GNG3,RIGI,SRP54,EEF1A1,SMCHD1,ABCB9,RIT2,CCT5,ENTPD3,RAB31,MCM3,DIRAS3,RAB37,NUDT1,CCT7,GNL1,MMAA,GNAZ,CLU,TUBB4B,RASD1,ATP6V1A,NUDT12,CFTR,RAB4A,ATP5F1B,GNA14,RHEB,SEPTIN7,RAB30,DIRAS1,AGAP2,MCM8,MLH3,DDX1,RERG,BCS1L,RAB11B,PLPP6,TUBB,NUDT2,SMC4,DDX39B,DDX39A,KIF3B,RAB23,DNM2,FHIT,ATP2C1,RALB,MX1,NUDT5,GNA11,NUDT19,KATNAL1,IFT22,RFC3,MORC4,ATAD1,GPN2,ALPL,HSPA5,SHOC1,DDX50,ATP1A3,MTG1,SAR1B,MMUT,ERCC3,NLRP3,MOV10,RAP2C,RND2,RGS2,DDX23,RHOBTB3,RABL2B,DIRAS2,RAB13,RHOB,RAB22A,HSPA8,SLC25A42,RAB32,RAB3A,GNG10,GFM1,ABCG2,EIF4A2,RAB1B,RAB5C,RAN,RAB14,NUDT9,DDX42,PSMC3,GNAI2,ARF4,RAB28,MFN1,ABCF1,RAB27A,RAB6B,GTPBP2,RASL10A,PLPP4,TPPP,MCM6,TOR3A,DDX4,IFIH1,RUVBL1,GNB1,MX2,RUVBL2,RND3,RFC2,DCTPP1,DRG1,GNAI3,CLPX,MORC2,RGS1,CCT8,RAP1B,NUDT16,EIF5B,TWNK,ATP1A2,EEF2,ARL11,COQ8B,DCP2,ATP5F1A,RAB9A,MRAS,RRAGB,RAB3B,ATP6V1G2,RAB35,GNG5,MCM4,ATP2B4,RGS5,XRCC5,NUDT3,NUDT4,ATP1A1,ABCC5,TOR1B,RGS6,HSP90AA1,AGAP1,GFM2,KIF1C,RAB1A,RAB18,RAB3D,RAP1A,RIT1,ARL4A,CDC42,ERAS,DRG2,PSMC1,GNGT2,GNAQ,DHX15,APTX,SMARCA5,NUDT7,RHOJ,RAB39B,DHX38,RAB29,HSP90B1,ARL5B,RASL12,RAB5A,RAC2,RHOH,RAB9B,G3BP1,ARHGAP5,NKIRAS2,PSMC4,RHOG,ARL10,RAB33B,ADPRM,RAB19,GNB3,RAP2A,RGS10,GNG11,HRAS,RFC4,DHX16,GNAO1,RALA,TRIM23,ABCE1,ACTB,TCP1,HSPD1,KIF2A,ATP6V1G1,MTG2,NTPCR,ARF1 |
| 1.754e-02 | -4.04 | BLMH (bleomycin hydrolase) | protein interactions | 642 | 127 | 47 | 19454 | 5460 |
HNRNPD,COPS5,G6PD,CD274,SYNCRIP,HRAS,CYP2C8,CHMP4C,RPL29,TNPO2,FCF1,TP53,DHX16,G3BP1,SETD7,MAPRE1,YWHAZ,NTAQ1,CASP4,GORASP2,CTSD,MYC,SFN,TNPO3,CLIC4,YES1,CALML5,GTF2A1,UBE2I,CCNF,SH3GLB2,WTAP,RPA2,NUDT12,METTL14,CDC42,CFTR,CDSN,LZTFL1,HSPA8,JADE1,RAP2A,RPA3,DDX39B,BAP1,PML,THUMPD1 |
| 1.758e-02 | -4.04 | phagocytic vesicle | cellular component | GO:0045335 | 141 | 53 | 19108 | 5553 |
PIP4P2,PIP4P1,VAMP8,RAB31,RAB8B,SLC48A1,ITGAV,VAMP3,LAMP2,TLR1,DNM2,CALR,OCRL,ATP6V0E1,CDC42,VAMP7,RAB11A,TAPBP,TLR2,B2M,SEC22B,PLA2G5,STX8,CDC42EP2,PDIA3,RAB14,RAC2,STX6,STXBP1,RAB32,SYK,RAB5A,TLR9,TLR6,RAB11B,HGS,STX12,ITGB5,VPS26B,MCOLN1,RAB9B,ZYX,ATP6V0B,RAB22A,RAB9A,CDC42EP4,TLR7,SLC15A2,SNAP23,SNX3,RAB23,CD36,BECN1 |
| 1.759e-02 | -4.04 | positive regulation of mononuclear cell migration | biological process | GO:0071677 | 92 | 37 | 18204 | 5365 |
P2RY12,CCR1,CX3CR1,MED23,MSTN,SELENOK,LGALS3,TNFRSF14,CXCL10,CCL5,TNF,CD47,CX3CL1,DEFB124,IL34,MMP14,XCL1,CALR,MADCAM1,CXCL13,OXSR1,CCR6,AIF1,CCR7,CCR2,CCL20,AGER,CREB3,PYCARD,HMGB1,CCL21,CCL3,CXCL12,RARRES2,IL12A,CD99L2,CCL1 |
| 1.762e-02 | -4.04 | CD74 (CD74 molecule) | protein interactions | 972 | 152 | 55 | 19454 | 5460 |
CD1D,TMEM254,TMEM243,HADHA,GTF2I,EDDM3B,BET1,PGRMC1,CNPY3,SEC22A,EIF3J,EIF2B3,CMTM7,FDFT1,ARCN1,PLP1,EIF3K,GANAB,POLR3B,COPE,PSMD6,PRRC2A,TM4SF20,HMOX2,ASCC1,EIF3G,YWHAZ,PDCD4,MAP1B,CLEC7A,ERG28,HAPSTR1,PCNA,PGA4,TMEM60,HUWE1,VDAC1,FKBP8,EIF3E,TUBA1A,CCR1,SNRPE,PHB1,RWDD1,EIF2S1,EIF2B5,MIF,TMEM97,PSMD3,PLPP4,EIF3D,FXYD6,OSBPL8,PDAP1,YWHAB |
| 1.767e-02 | -4.04 | Ligand-dependent caspase activation | REACTOME pathways | R-HSA-140534 | 17 | 10 | 10285 | 3229 |
CD14,TLR4,TICAM1,TNFSF10,FAS,FASLG,TICAM2,TLR3,LY96,TRAF2 |
| 1.767e-02 | -4.04 | exit from host cell | biological process | GO:0035891 | 28 | 14 | 18204 | 5365 |
TSG101,CHMP4C,CHMP2B,PC,VPS4B,CHMP2A,CAV2,CHMP5,CHMP1A,PPID,CHMP1B,TRIM62,VPS4A,PPIA |
| 1.767e-02 | -4.04 | response to iron ion | biological process | GO:0010039 | 28 | 14 | 18204 | 5365 |
SLC6A3,SLC11A2,MDM2,HFE,G6PD,FXN,CYBRD1,BECN1,ACO1,B2M,MAP1LC3A,CYP1A1,TF,TFRC |
| 1.767e-02 | -4.04 | viral release from host cell | biological process | GO:0019076 | 28 | 14 | 18204 | 5365 |
CHMP1B,CAV2,CHMP5,PPID,PC,CHMP2A,TSG101,TRIM62,PPIA,VPS4A,CHMP1A,VPS4B,CHMP4C,CHMP2B |
| 1.767e-02 | -4.04 | negative regulation of heart growth | biological process | GO:0061117 | 28 | 14 | 18204 | 5365 |
SAV1,G6PD,PI16,RGS2,MIR25,FOXP1,MIR873,PPARA,CAV3,VGLL4,TOMM70,NOG,GSK3A,MIR1-1 |
| 1.767e-02 | -4.04 | negative regulation of cardiac muscle tissue growth | biological process | GO:0055022 | 28 | 14 | 18204 | 5365 |
NOG,MIR1-1,GSK3A,VGLL4,TOMM70,CAV3,PPARA,MIR873,FOXP1,PI16,MIR25,RGS2,G6PD,SAV1 |
| 1.767e-02 | -4.04 | regulation of monocyte chemotaxis | biological process | GO:0090025 | 28 | 14 | 18204 | 5365 |
DEFB124,CXCL12,CREB3,CCL1,GREM1,DUSP1,HMGB1,CXCL10,CCN3,CCR2,CX3CR1,CCL5,AIF1,CCR1 |
| 1.770e-02 | -4.03 | CALU (calumenin) | protein interactions | 813 | 319 | 107 | 19454 | 5460 |
CHMP4C,HDAC11,EZH2,RPN1,OTULIN,RAF1,TPD52,B3GNT2,FAF2,ASPM,TUBA1A,EIF2D,IMMP2L,SAR1B,PDIA6,ERP29,PCNA,TAF7,PDIA3,PPIB,DNAJB9,COX14,CNTROB,EGLN3,CYP3A5,FKBP10,BET1,CNPY3,EMC1,MRPS7,PXMP2,TMEM106B,DNAJC3,EP300,AKAP1,HSPA8,TMEM256,H1-10,ILK,OSGEP,SP1,CUL3,RAB11A,MYC,BTF3,TOMM40,UMPS,SSH3,MTM1,ESR2,VDAC2,SEC61B,PRMT5,ACTR2,TMEM165,ARPC3,HSPA13,TFRC,SH3GLB1,CCDC47,DNAJC30,PTGES3,RNASEL,RIGI,SFXN1,IGF1R,THG1L,HSD17B10,ERO1A,SNRNP70,BRD3,FAM20C,DPP4,CALR,CSNK2A1,LMAN1,RCHY1,COX4I1,RPL32,COQ8A,TES,CHID1,HSP90B1,PTPN22,P3H1,RPA2,RPRD1B,MET,SH3GLB2,ATG16L1,CFTR,FBXW7,HSPA5,BAP1,ARPC2,RAB9A,DNAJC10,NIF3L1,SDF2L1,UBE2H,CTSB,VIRMA,SEC63,UBE2I,MSN,INTS12,GANAB |
| 1.772e-02 | -4.03 | neutrophil chemotaxis | biological process | GO:0030593 | 55 | 24 | 18204 | 5365 |
CXCL3,CXCL1,PDE4B,PIK3CG,S100A8,JAML,CXCL13,PPIB,CXCR1,IL1B,CKLF,CCL3,SYK,PPIA,CXCL11,XCL1,FCER1G,TGFB2,CXCL8,SRP54,DPEP1,LGALS3,CXCL10,CXCL9 |
| 1.772e-02 | -4.03 | regulation of striated muscle cell apoptotic process | biological process | GO:0010662 | 55 | 24 | 18204 | 5365 |
BAG3,MIR24-1,BMPR1A,HSPA8,TP53,MIR30E,MIR106B,MIR17,MIR320A,NFE2L2,JAK2,MIR20A,MIR34A,HAND2,MIR21,SMAD4,PPP1R10,NUPR1,RGL2,MIR195,CAPN2,MIR145,HEY2,MIR16-1 |
| 1.772e-02 | -4.03 | regulation of cellular senescence | biological process | GO:2000772 | 55 | 24 | 18204 | 5365 |
MIR146A,CDK6,MIR590,MIR10A,AKT3,BCL6,TERC,ZMPSTE24,MIF,MIR17,VASH1,ING2,CGAS,FZR1,MIR34A,MAP3K3,B2M,TERT,ARG2,TP53,BMPR1A,PTEN,MIR188,EEF1E1 |
| 1.772e-02 | -4.03 | positive regulation of alpha-beta T cell differentiation | biological process | GO:0046638 | 55 | 24 | 18204 | 5365 |
KLHL25,LILRB4,MIR21,CCL19,TGFBR2,ZBTB16,FOXP3,NLRP3,RUNX1,PNP,IL18,CD83,SOCS5,SYK,NKAP,SASH3,IL2RG,CD86,CD80,CBFB,IL23A,IL12B,IFNG,EP300 |
| 1.773e-02 | -4.03 | mixed_carcinoma | COSMIC cancer mutations | mixed_carcinoma | 26 | 13 | 16828 | 4835 |
PTEN,DICER1,SMAD4,PIK3CA,IDH1,FBXW7,PPP2R1A,IDH2,CTNNB1,KRAS,KIT,TP53,BRCA1 |
| 1.773e-02 | -4.03 | retinoblastoma | COSMIC cancer mutations | retinoblastoma | 26 | 13 | 16828 | 4835 |
RUNX1,SF3B1,EWSR1,STOML2,HRAS,KRAS,PIK3CA,PTEN,RB1,KIT,JAK2,AKT1,FBXW7 |
| 1.773e-02 | -4.03 | eye-retina-retinoblastoma | COSMIC cancer mutations | eye-retina-retinoblastoma | 26 | 13 | 16828 | 4835 |
FBXW7,JAK2,AKT1,RB1,KIT,PTEN,PIK3CA,HRAS,KRAS,STOML2,RUNX1,EWSR1,SF3B1 |
| 1.773e-02 | -4.03 | lung-carcinoma-acinar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-acinar_adenocarcinoma | 26 | 13 | 16828 | 4835 |
TP53,KRAS,CTNNB1,MET,FBXW7,AKT1,PIK3CA,MAP2K1,SDC4,FGFR1,STK11,SMAD4,PTEN |
| 1.773e-02 | -4.03 | gastrointestinal_tract_(site_indeterminate) | COSMIC cancer mutations | gastrointestinal_tract_(site_indeterminate) | 26 | 13 | 16828 | 4835 |
TNFAIP3,SMAD4,MYD88,STK11,TERT,PIK3CA,JAK2,FBXW7,KIT,MET,KRAS,CTNNB1,TP53 |
| 1.773e-02 | -4.03 | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I | 34 | 16 | 16828 | 4835 |
GNAQ,CLCN6,IDH1,KRAS,PTEN,PIK3CA,FGFR1,PPP2R1A,FBXW7,IDH2,AKT1,NACC2,CTNNB1,GNA11,KIT,MET |
| 1.780e-02 | -4.03 | Class A/1 (Rhodopsin-like receptors) | REACTOME pathways | R-HSA-373076 | 322 | 119 | 10285 | 3229 |
ADORA3,GPBAR1,GRPR,HTR1A,NPY1R,PTGER4,GNRH1,CCR5,CCR6,CCR2,HEBP1,P2RY10,CCR4,OXTR,CHRM1,PDYN,GNRHR2,HTR5A,GPHA2,LHB,CXCL12,CXCL9,NPY,CNR1,MLN,UTS2R,GPR37,OPRM1,PNOC,HRH3,LPAR1,GNRH2,CCL21,LPAR6,NPY2R,CCL5,P2RY4,ADRB1,CCL28,HTR2A,DRD3,PLPPR1,SST,ADRB3,CXCL11,NPBWR1,TAAR1,CHRM5,XCL1,P2RY11,F2,PPY,CCL27,S1PR4,CHRM4,TSHR,CCL1,PTGER1,CCR7,APLN,NPY5R,LPAR2,CXCR6,CXCL3,HCAR1,OPRL1,DRD1,MCHR1,CCL23,ACKR3,ADORA1,TAAR6,CXCL10,HRH2,CXCR1,EDNRA,CCL25,GPR17,GHRL,TACR3,GPR37L1,ADRA1A,P2RY12,NMBR,NPSR1,NPW,ADRB2,CCL19,NPB,UTS2,CXCR4,TAC1,CXCL1,APLNR,CCR1,TACR1,CCL20,MCHR2,P2RY1,OPRK1,BRS3,HTR1F,GPR35,PTGFR,PROK1,GPR65,CX3CR1,RLN2,CX3CL1,RLN3,AVPR1B,CCR3,CXCR3,RXFP2,PTGER2,CXCL13,HCRT,CXCL8,CHRM3 |
| 1.780e-02 | -4.03 | KMT2C (lysine methyltransferase 2C) | protein interactions | 58508 | 124 | 46 | 19454 | 5460 |
HNF1B,CUL3,KANSL3,AR,CDC73,SMAD2,BUB3,DYNLL1,FBXO22,ESR2,VIRMA,RPA2,PPARG,GRM2,PAX9,ELF5,KLF4,BAP1,RPA3,HCFC2,FOS,CXXC1,CALR,IRF4,DPY30,HAX1,LHX2,WDR82,HNRNPL,PRNP,NUP35,TOP3B,EGR2,SOX2,JUN,SOX9,EZH2,SMARCB1,PABPC1,TCOF1,CLPB,RING1,H3C1,KDM4B,PAGR1,PAX6 |
| 1.780e-02 | -4.03 | T cell costimulation | biological process | GO:0031295 | 44 | 20 | 18204 | 5365 |
SRC,CD274,AKT1,CAV1,CCL21,PIK3CA,TNFRSF14,ICOS,CD40LG,CD81,YES1,PDCD1LG2,CD86,CSK,PTPN11,CD28,CD80,EFNB1,CCL19,DPP4 |
| 1.780e-02 | -4.03 | regulation of ubiquitin-protein transferase activity | biological process | GO:0051438 | 44 | 20 | 18204 | 5365 |
SKP1,RPS7,ARRDC3,UBE2L3,FBXW7,TOPORS,RPS2,RPL23,UBE2S,CDC20,FZR1,MAD2L1,CDKN1B,FEM1A,PTEN,MAGEC2,MAD2L2,FEM1B,BAG2,RBCK1 |
| 1.783e-02 | -4.03 | chloride channel regulator activity | molecular function | GO:0017081 | 13 | 8 | 18094 | 5411 |
VAMP8,STX7,CHRNA7,CFTR,STX1A,VTI1B,NHERF1,STX8 |
| 1.785e-02 | -4.03 | PACSIN2 (protein kinase C and casein kinase substrate in neurons 2) | protein interactions | 11252 | 171 | 61 | 19454 | 5460 |
FASLG,VDR,KIAA0408,GTF2E2,EXOSC8,DIPK1A,RND3,HSPD1,PPP1R12A,EWSR1,NTRK2,THG1L,KRAS,EPHA4,RAB3B,WASL,PTGES3,MOV10,DPP4,RHOG,CRTAP,CCDC71,RAB35,DNM2,SWAP70,ARF6,PRNP,CCAR2,RHOH,DIRAS3,STX6,CAV1,RND2,EHD1,CDC42,HSP90B1,FGFR1,SLU7,BAP1,RHOU,SYVN1,HSPA8,RAB5A,CYFIP2,UGP2,STX7,PACSIN3,FTL,CARS1,HNRNPC,RAB11A,DNAJC5,ST13,LAMTOR1,RHOB,FTSJ3,NTRK3,STK11,ACOX1,CLXN,RHOJ |
| 1.785e-02 | -4.03 | PLSCR1 (phospholipid scramblase 1) | protein interactions | 5359 | 171 | 61 | 19454 | 5460 |
PCED1A,DLK2,SHC1,CNTFR,SLC2A1,ZNF688,CD63,HRAS,PLSCR3,ARL6IP5,RAF1,GDE1,YIPF3,ZNF581,NECAP2,NTN4,STK16,CRKL,BACE1,FAM168A,EWSR1,NOC4L,LASP1,KRAS,ZBTB16,TFG,ENKD1,RERE,SLC35A2,PPDPF,PDE2A,GPR17,MGAT5B,SLPI,REEP6,BOLA1,DHRS1,FAM107A,SCNM1,STUM,RETREG3,HEY2,ESR2,GNAI2,SRC,APEX1,PRR13,PLSCR4,DIO3,SIGMAR1,FRS3,NUFIP2,FAM8A1,VSIR,PML,EP300,RAMAC,CRY1,TACR1,SMCP,RASD1 |
| 1.785e-02 | -4.03 | CWF19L2 (CWF19 like cell cycle control factor 2) | protein interactions | 143884 | 171 | 61 | 19454 | 5460 |
PRPF19,GAS8,DDX23,NAB2,HOMER3,SDHAF2,SNRPA1,SNRPD3,COMMD6,HNRNPL,CDC5L,CNTROB,DKC1,SUPT5H,TRAF2,DISC1,CBX3,AAMP,SNRPE,RINT1,DHX9,PICK1,TRIM37,KRAS,TSSC4,SNRPG,STX11,HNRNPC,CEP70,SNRPB,TBC1D1,TRIM23,BRCA1,UBE2H,ELAVL2,EXOC8,ZNF330,ZNF655,TRIM27,SF3B4,CSNK2B,SNRNP40,TAX1BP1,TRIM54,SNRPB2,APEX1,DES,SNRPN,PABPC5,ATG16L1,WDR83,LMNA,TFIP11,PML,DVL2,COMMD2,CWF19L1,FXR2,PTN,NHP2,COIL |
| 1.786e-02 | -4.03 | PIWI-interacting RNA (piRNA) biogenesis | REACTOME pathways | R-HSA-5601884 | 29 | 15 | 10285 | 3229 |
POLR2B,DDX4,PIWIL2,PIWIL1,HENMT1,PIWIL4,HSP90AA1,ASZ1,MAEL,POLR2L,POLR2I,POLR2D,POLR2C,POLR2G,POLR2F |
| 1.786e-02 | -4.03 | Inflammatory bowel disease (IBD) | KEGG pathways | ko05321 | 65 | 31 | 7161 | 2463 |
STAT1,JUN,IL2RG,NFKB1,IL17F,TLR2,IL22,IL10,TLR5,IL6,IL1B,IL21,IL1A,TNF,SMAD2,FOXP3,TGFB3,TGFB2,STAT6,IFNG,SMAD3,IL4,IL5,IL23A,IFNGR1,IL12B,IL12A,IL2,IL18,TLR4,IL13 |
| 1.786e-02 | -4.03 | Inflammatory bowel disease (IBD) | KEGG pathways | hsa05321 | 65 | 31 | 7161 | 2463 |
IL5,IL23A,IFNGR1,IL12A,IL12B,IL2,IL18,TLR4,IL13,TGFB2,TGFB3,STAT6,IFNG,IL4,SMAD3,IL17F,TLR2,IL22,IL10,IL6,TLR5,IL21,IL1B,IL1A,TNF,SMAD2,FOXP3,STAT1,JUN,IL2RG,NFKB1 |
| 1.790e-02 | -4.02 | regulation of TORC1 signaling | biological process | GO:1903432 | 95 | 38 | 18204 | 5365 |
PIP4P1,STK11,RNF167,TBK1,CSNK1A1,UBE2N,C9orf72,UBE2D1,GPR137,LAMTOR1,SYK,KLHL22,LAMTOR3,CUL3,AKT1,CASTOR2,MIOS,SRC,SESN2,RHEB,PRKACB,YWHAZ,SESN3,SEC13,RNF152,FLCN,PIH1D1,KICS2,LAMTOR2,STAMBPL1,SLC38A9,EP300,UBE2W,YWHAG,RRAGA,SAR1B,UBE3A,RRAGB |
| 1.791e-02 | -4.02 | ADIPOR1 (adiponectin receptor 1) | protein interactions | 51094 | 46 | 20 | 19454 | 5460 |
AQP3,NFKBIL1,TSPAN3,STK11,TSPAN10,RAB2A,GINM1,MOV10,MYC,TMEM231,KRAS,GNAI2,OPRL1,TACR3,TSPAN15,RUSF1,RHOU,DPH3,TACR1,BSCL2 |
| 1.791e-02 | -4.02 | TCL1B (TCL1 family AKT coactivator B) | protein interactions | 9623 | 46 | 20 | 19454 | 5460 |
SNRPG,SAR1B,MED17,LSM5,PTEN,ZNF330,PNMA1,AKT2,MED4,MED29,DISC1,MED23,MED10,HPS6,TNPO2,MED9,MED22,ARFGEF1,AKT1,NDE1 |
| 1.791e-02 | -4.02 | DGAT2L6 (diacylglycerol O-acyltransferase 2 like 6) | protein interactions | 347516 | 46 | 20 | 19454 | 5460 |
GAD2,ZC3H11A,HSD17B11,RUSF1,TMX2,MYG1,REEP4,MPP1,RNF5,TUFM,ABHD5,FBXL19,SCN3B,ABHD4,TMEM14B,SMG9,SCAND1,FCER1G,STAR,TMEM31 |
| 1.791e-02 | -4.02 | KCNH2 (potassium voltage-gated channel subfamily H member 2) | protein interactions | 3757 | 46 | 20 | 19454 | 5460 |
RHOH,FRMD8,FKBP8,RIGI,RMND1,SMAD5,STUB1,HSPA8,BAG2,NDUFS6,SIGMAR1,HSP90AA1,RNF139,CDC73,TOP3B,KCND3,CALR,RAB11A,YWHAH,CAV3 |
| 1.791e-02 | -4.02 | TRIB1 (tribbles pseudokinase 1) | protein interactions | 10221 | 46 | 20 | 19454 | 5460 |
CEBPE,JUNB,VIRMA,SLAIN2,FOS,HAPSTR1,FOSL2,MAP2K1,BECN1,COP1,RASSF8,KLC2,ACACA,TRIB1,MYC,TOP3B,UBXN6,PDE8A,HSPB8,DET1 |
| 1.791e-02 | -4.02 | LAD1 (ladinin 1) | protein interactions | 3898 | 46 | 20 | 19454 | 5460 |
METAP2,ACOX1,GID4,MKLN1,HECTD3,EPHA4,ESR2,POLDIP2,OLA1,RPL7A,SFN,ZMYND19,TOP3B,RAF1,CTNNB1,CFTR,FEM1A,NCK1,SPOP,ARMC8 |
| 1.791e-02 | -4.02 | PGM2 (phosphoglucomutase 2) | protein interactions | 55276 | 46 | 20 | 19454 | 5460 |
ETFA,AKR1C2,VIRMA,MPST,RPA3,GATD3,GLTP,STX17,AGR2,RPA2,SMAD4,HSPB1,MDH1,CCR1,ETFB,BAG3,PGM1,SOX2,MAP1LC3B,COPS5 |
| 1.791e-02 | -4.02 | TRIM10 (tripartite motif containing 10) | protein interactions | 10107 | 46 | 20 | 19454 | 5460 |
HGS,POLR1B,HSP90AA1,UBE2D1,TTC23,IFNAR1,EMILIN3,FAM193B,TBK1,TRIM35,UBE2D3,PSMA1,TRIM11,SEMG2,ZMYM2,HAPSTR1,TRIM10,ZBTB33,SCNM1,TRIM44 |
| 1.791e-02 | -4.02 | DIS3L (DIS3 like exosome 3'-5' exoribonuclease) | protein interactions | 115752 | 46 | 20 | 19454 | 5460 |
SNRNP70,BICD2,EXOSC3,EXOSC1,MPHOSPH6,RBM7,GTPBP1,CDKN3,XPO1,H2AX,EXOSC8,EYA3,STAU1,RNF20,BTG3,LCN15,EIF4E2,HAPSTR1,EXOSC4,C1D |
| 1.791e-02 | -4.02 | RADX (RPA1 related single stranded DNA binding protein, X-linked) | protein interactions | 55086 | 46 | 20 | 19454 | 5460 |
USP14,NUDCD3,TP53,IFI16,HEXIM1,DNAJC7,LMNA,CDK8,RPL31,CD274,CCNF,RAB8B,MDC1,APEX1,EGLN3,AIPL1,RADX,ASF1A,UFL1,PLEKHF2 |
| 1.794e-02 | -4.02 | protein-containing complex binding | molecular function | GO:0044877 | 1772 | 569 | 18094 | 5411 |
RAN,H2AC1,SCAMP5,NDUFAF2,UHMK1,SNRPB,ARPC2,GNAI2,PHF21A,CDK1,KCNIP2,CETN3,MMP14,PTN,CD2BP2,NCKIPSD,PTPRZ1,F11R,LHX2,ISG15,WDR82,ANXA7,TUBA1A,USP13,IRF3,CACNB2,H2AZ2,RPLP1,GNB1,FGF1,RUVBL1,RUVBL2,TFRC,ZNHIT1,MITF,SMAD4,ICAM2,LMBRD1,VLDLR,DYNC1I1,MORC2,TOP1,SPTAN1,TMEM147,MYC,FOXC2,CTBP1,CDH13,RNF5,ITGB5,MB21D2,CAPZA2,EDF1,DERL1,H1-3,CINP,ING2,MDM2,MSH6,HELLS,CAMSAP2,HOMER1,GAS2,TOX,RBM23,HDAC3,TAGLN2,APEX1,SESN2,TRIM24,ACVR1,NOPCHAP1,PLS3,EIF1B,ARPC3,PRMT6,DCTN6,NUF2,H1-6,NFKB1,LDLR,LACRT,RS1,RAP1A,SGTA,PYM1,GNAQ,CGAS,ITGA2,KMT5B,CFL1,PCSK9,AIF1,IL1B,SYK,DNTTIP1,SMARCA5,EIF5A2,MBD3,B2M,SUV39H1,TSHR,NDUFA4,CDK9,PPIB,BCL10,LCP1,CTNNA1,POLR2B,ATF1,HNRNPC,SLC6A4,CRTAP,CKS2,PAFAH1B1,TACO1,GNB3,FGR,CD4,RING1,H2AX,PPIH,TGFBR2,H2AC4,CITED1,ACTB,MEIOB,SNAI2,YTHDF1,TGFB3,DNAJC2,ACSS2,PCNA,ING5,PPP3CA,EED,EPCAM,HPF1,NAA15,TRAF2,CCDC47,CSNK2B,DDX5,IKZF5,CALR,BIRC2,POLDIP3,CD36,ADORA1,HADHA,KLRD1,MYH2,WBP2,TMA16,CAPG,PRMT5,STPG4,PICK1,XPO5,LASP1,HBE1,CDKN1B,FCGR2A,MTA3,VIPAS39,IL12B,COL3A1,PPARG,BAHD1,SOX14,SNX3,KDM1A,H2AC13,POLE3,HEXIM1,CD3G,CD226,TPM3,SPP1,SEC61A2,ELK4,USP16,RERE,EIF2S1,SEC61G,EIF4A3,SEMA7A,CTSK,DHX9,KBTBD13,CD40LG,VPS4B,LRWD1,KRAS,TAF10,ZNF609,IFNA13,GMNN,SLC6A3,HCLS1,EGR2,NF2,ADRM1,SRP54,ITGA6,MAIP1,FCER1G,SIRT7,NAA16,PHF13,SNRPD3,CAV1,ACTL6B,HTR2A,GADD45A,SPATA2,TAPBP,RBM3,PHC1,GNAZ,DLG4,TSNAX,CAV3,USP14,SEC61A1,SMARCE1,LEMD3,CFTR,ADM2,GNA14,PPARA,NAPA,ITGAV,MCM8,DDX1,EZH1,AP2A1,CXCL12,TAF7,SMC4,GTF2B,UBE2S,ABITRAM,TLR2,H2AB1,MADCAM1,FZR1,SCML1,MSL2,LILRA2,DSTN,KLRC2,USP3,NAP1L3,GNA11,UBLCP1,PELO,ENY2,ERCC3,AGER,CDK5R1,NUPR1,VWF,LCA5,BAG3,HSPA8,C1QTNF1,TAB1,FZD4,HDAC5,PRKCB,CBX3,MEF2A,SOX9,TEF,RELL2,HP1BP3,JAML,FBXW11,HIRA,SDCBP,RNASEL,PAFAH1B3,ACVR1B,IFRD2,H1-5,FERMT2,ZNF304,TOX4,SMARCD3,NKAP,GRIA1,PHAX,IGF1R,LGALS3,CYRIB,PRMT2,FBLN5,RPSA,CEBPE,MTRES1,IFIH1,ADRB2,SMAD2,KLF4,CREBBP,NOP58,SNRPN,GNAI3,CUL2,HR,GABPA,MTA2,EGR1,GCLC,ASF1A,SRP72,LDB1,RAP1B,E2F4,TP53,FCMR,EEF2,GARRE1,SSBP1,ELK1,NONO,CORO1C,DRD1,DET1,GUCY1B1,H2AJ,MECP2,GPNMB,DAG1,NDN,BEND6,TSG101,SEC61B,PPP1CC,GAD2,SUPT5H,BOK,NEFL,KRT8,XRCC5,STAT1,EIF3K,ATG101,CDKN1A,LILRB1,TSSC4,CD151,CTNNA2,HSP90AA1,WDR12,TAF2,SUCLG2,SSRP1,HDAC6,ADD2,ATP5IF1,ETF1,PEX26,DYNLL1,MIR9-1,GLRB,SERPINH1,LGALS8,MYH1,ITGB8,STK11,TRIM37,CD2AP,CETN2,MACROH2A2,APTX,SMARCB1,BICD2,SRC,GPIHBP1,RNF20,CBX5,SCML2,PTEN,CNN3,RAB29,MLLT6,FHOD3,NUP62,PELP1,SQSTM1,GTF2F1,H1-10,ZNHIT6,PRNP,SECISBP2L,DLX1,PRKCA,NUCKS1,ACTN4,CAPN2,JCHAIN,CAPZA1,G3BP1,FCGR2B,MLC1,MALSU1,AIF1L,RAD23B,TBC1D5,BAP1,EMILIN1,ACTR3B,GNAO1,CIB2,ABCE1,NME1,HSPD1,EP300,SNRPA,MBD5,IFNA10,ADNP,ZNF593,MAP1S,PAX6,MACROH2A1,BAK1,SAP30L,FCGR1A,TULP3,CPEB1,TERC,PHF1,ACTR2,FCAR,CCNF,HMGA1,OLA1,MYO1B,DISC1,FLCN,DPPA2,HINFP,VPS4A,CORO6,PLAC8,FOS,H1-1,CRYAB,PIWIL2,HSP90AB1,ADGRG1,NPM3,NHERF1,RAD21,BRD3,TAPBPL,NR1H2,ACTL6A,BCL6,LZTFL1,SIN3A,SETD7,SRPRA,PCLAF,CFL2,PSMG4,RPS3,HMGN4,IFNA2,MCMBP,THY1,CTNNB1,TXNRD2,DDR1,PRPF31,LIMD2,HMGB1,CCN3,ATP1B1,MYO6,CD9,CALY,H2AC6,EPOP,ICAM1,SMAD3,IFNB1,COCH,WASF3,MARCKSL1,RIT2,H2AZ1,TMEM70,LUM,TSSK1B,GTF2E2,RBBP4,ACHE,EMP2,NCOA5,RPL23A,P3H1,PSMG3,UQCRC1,BARX2,PSMD14,WRAP53,CX3CL1,AP1AR,SCFD1,FOSL2,IFTAP,CLU,CHRNB2,INHA,ATF4,GNB4,MLH3,TFPT,LAMB2,TAGLN3,PQBP1,TUBB,SLC25A3,MAP1B,TOP2B,ZNF622,IMPACT,KIF3B,STOML2,RNF8,VPS28,COTL1,IFNK,PLP1,CTSB,IGF1,H2AC7,CDC20,ICAM3,PCGF2,RBPJ,ADD1,AR,NDUFAB1,MMP9,SLC25A46,HSPA5,SPTBN1,PIWIL1,PARP2,TSPYL4,FRRS1L,NACC2,PLCB2,ALOX5AP,CFAP73,EZH2,CD81,PKNOX1,PPIA,HNRNPD,DERL2,PAFAH1B2,RAB32,H2AC25 |
| 1.798e-02 | -4.02 | WDFY2 (WD repeat and FYVE domain containing 2) | protein interactions | 115825 | 32 | 15 | 19454 | 5460 |
SYP,GPD2,GDI2,DNTTIP1,UTP6,DSN1,PNOC,MIEF1,RBM17,ZBED1,EFNB1,MTDH,YIF1A,VAMP3,RPRM |
| 1.798e-02 | -4.02 | FUT1 (fucosyltransferase 1 (H blood group)) | protein interactions | 2523 | 32 | 15 | 19454 | 5460 |
NDUFB8,C1GALT1C1,TMX4,HFE,GLT8D2,TMEM59,CSGALNACT2,TOP3B,NDUFB6,HS2ST1,B4GALT7,HTRA1,NDUFC2,NDUFB4,NDUFB5 |
| 1.798e-02 | -4.02 | CXCL8 (C-X-C motif chemokine ligand 8) | protein interactions | 3576 | 32 | 15 | 19454 | 5460 |
HDAC3,CCL2,CCL8,GNAI2,IL12A,SGTA,MMP9,EP300,IKBKB,ARFGAP3,CXCR1,NFKB1,TP53,CCL5,CXCL8 |
| 1.798e-02 | -4.02 | TRIM62 (tripartite motif containing 62) | protein interactions | 55223 | 32 | 15 | 19454 | 5460 |
SFN,SNAP29,MYC,TRIM62,UBE2E3,UBE2D1,SMAD2,SMAD3,FAIM,NRGN,PPP1R18,UBE2D3,UTP25,GLRX,CNTROB |
| 1.798e-02 | -4.02 | ASB4 (ankyrin repeat and SOCS box containing 4) | protein interactions | 51666 | 32 | 15 | 19454 | 5460 |
STUB1,HSPD1,DNAJB4,RPS27L,FARSA,CUL2,HSPB8,IQSEC1,TFRC,UBE2D1,RNF7,ASB7,HSP90AA1,HSPB1,RIT1 |
| 1.798e-02 | -4.02 | INPP5A (inositol polyphosphate-5-phosphatase A) | protein interactions | 3632 | 32 | 15 | 19454 | 5460 |
RABGGTB,DHX9,TTC1,RCCD1,CERS2,HNRNPL,TTR,SPPL3,NR2F6,DUSP22,CENPM,ACACA,H1-1,MED21,YWHAZ |
| 1.798e-02 | -4.02 | DAPP1 (dual adaptor of phosphotyrosine and 3-phosphoinositides 1) | protein interactions | 27071 | 32 | 15 | 19454 | 5460 |
FAIM,TNFAIP1,GSTCD,APBB3,FCHSD2,SRC,TM4SF19,ZNHIT1,MYLIP,PTPN11,MGARP,WDR20,RPL23,FXN,CNDP2 |
| 1.798e-02 | -4.02 | US3 (serine/threonine protein kinase US3) | protein interactions | 2703401 | 32 | 15 | 19454 | 5460 |
HSP90AA1,CCT2,EEF1A1,ACOT8,PRDX1,IFI16,HSP90AB1,PRDX4,TUBB,TCP1,RPS16,HNRNPH2,CCT8,RPS3,SLC25A5 |
| 1.798e-02 | -4.02 | MTFP1 (mitochondrial fission process 1) | protein interactions | 51537 | 32 | 15 | 19454 | 5460 |
OPRM1,TOR1AIP2,CDKN2D,SLC22A8,AQP3,SLC39A9,CLPB,SLC2A8,TMEM108,HSCB,RAMP3,DUSP21,OPRL1,DUSP19,SLC5A6 |
| 1.798e-02 | -4.02 | TMEM129 (transmembrane protein 129, E3 ubiquitin ligase) | protein interactions | 92305 | 32 | 15 | 19454 | 5460 |
DERL2,UBE2D3,PSMD4,DERL1,TMX3,SYVN1,SFXN1,IDH3A,KCNA2,ESYT1,UCK2,UBE2D1,SLC30A5,SELENOS,TOP3B |
| 1.798e-02 | -4.02 | FKBP1B (FKBP prolyl isomerase 1B) | protein interactions | 2281 | 32 | 15 | 19454 | 5460 |
GMPPB,GLOD4,NME2,GSTO1,FKBP1B,ENO1,ENO2,SOD1,FABP5,BMPR1A,HINT1,HSD17B10,TAGLN3,TAGLN2,DDAH2 |
| 1.807e-02 | -4.01 | NRDC (nardilysin convertase) | protein interactions | 4898 | 121 | 45 | 19454 | 5460 |
EP300,BOLA3,RPA3,TNFSF12,NME4,HDAC3,STAU1,H2AB1,DHRS4,PIH1D1,MTRES1,P3H1,CCNF,IDE,RPL10,TSN,ATP5F1A,HBEGF,CSK,UBE2H,FBXW11,OPA3,PDIA6,PPP1R12A,HSPD1,PFDN1,IMMP2L,CHCHD2,GNL1,SOX2,AURKAIP1,TP53,XPO5,HP1BP3,EGLN3,STK3,COPS5,ACP6,MOV10,PFDN5,DNAJC7,PDYN,PPP3CA,HSPB1,CHCHD1 |
| 1.807e-02 | -4.01 | HASPIN (histone H3 associated protein kinase) | protein interactions | 83903 | 121 | 45 | 19454 | 5460 |
CNTN1,RP2,THBS3,SQSTM1,HADHA,CDK1,CSNK1G3,SPTBN1,CD59,MATR3,RALA,TMOD3,YES1,VIRMA,GNAI2,GNB1,GNG12,GLIPR2,RRAS2,MYC,MCM3,KPNA6,H3C1,TRIM37,RPL28,FLOT1,RIGI,CAPZA1,PPP1R12A,MAGED4B,MYO1B,HECTD3,EZH2,MOXD1,PNMA2,GNAI3,MARCKSL1,TP53,ACTN4,PRNP,SPTAN1,WDR6,CORO1C,ADD1,MDFI |
| 1.807e-02 | -4.01 | Prolactin signaling pathway | KEGG pathways | hsa04917 | 70 | 33 | 7161 | 2463 |
SOCS3,FOS,PIK3R1,ELF5,SHC3,KRAS,ESR2,PIK3R2,JAK2,AKT1,SHC1,SRC,HRAS,SOCS5,MAPK10,CISH,CCND1,RAF1,AKT2,STAT1,MAP2K1,AKT3,CYP17A1,LHB,STAT5A,NFKB1,IRF1,PRL,PIK3R3,PIK3CA,SOS2,SOCS4,SOCS2 |
| 1.807e-02 | -4.01 | Prolactin signaling pathway | KEGG pathways | ko04917 | 70 | 33 | 7161 | 2463 |
PIK3CA,SOCS4,SOCS2,SOS2,PRL,PIK3R3,IRF1,STAT5A,NFKB1,AKT3,CYP17A1,LHB,AKT2,STAT1,MAP2K1,CCND1,RAF1,SOCS5,MAPK10,CISH,SRC,HRAS,SHC1,JAK2,AKT1,ESR2,PIK3R2,ELF5,SHC3,KRAS,SOCS3,FOS,PIK3R1 |
| 1.807e-02 | -4.01 | KLRF1 (killer cell lectin like receptor F1) | protein interactions | 51348 | 9 | 6 | 19454 | 5460 |
REEP6,TOMM40,TP53,DESI1,GTF2I,CSK |
| 1.807e-02 | -4.01 | LMAN1L (lectin, mannose binding 1 like) | protein interactions | 79748 | 9 | 6 | 19454 | 5460 |
FKBP14,SPCS1,LMAN1,ESR2,TMEM38B,SPCS2 |
| 1.807e-02 | -4.01 | Rack1 (receptor for activated C kinase 1) | protein interactions | 14694 | 9 | 6 | 19454 | 5460 |
SNRPA,PTEN,CFTR,EEF1G,LARP4B,YTHDF1 |
| 1.807e-02 | -4.01 | TMEM213 (transmembrane protein 213) | protein interactions | 155006 | 9 | 6 | 19454 | 5460 |
ALG11,EFNB1,DCUN1D5,MAT2A,PGRMC1,METAP2 |
| 1.807e-02 | -4.01 | SEZ6 (seizure related 6 homolog) | protein interactions | 124925 | 9 | 6 | 19454 | 5460 |
METAP2,CHDH,PRNP,APEX1,SNX17,RPL23 |
| 1.807e-02 | -4.01 | SOBP (sine oculis binding protein homolog) | protein interactions | 55084 | 9 | 6 | 19454 | 5460 |
KLF3,CTBP1,HNRNPL,MIF,SUMO2,VIRMA |
| 1.807e-02 | -4.01 | Mcm2 (minichromosome maintenance complex component 2) | protein interactions | 17216 | 9 | 6 | 19454 | 5460 |
MCM3,MCM4,CDC7,MCM6,HSPB8,ECD |
| 1.807e-02 | -4.01 | VEPH1 (ventricular zone expressed PH domain containing 1) | protein interactions | 79674 | 9 | 6 | 19454 | 5460 |
ACVR1,TNFAIP3,TOP3B,BMPR1B,CFTR,SMAD1 |
| 1.807e-02 | -4.01 | ADIRF (adipogenesis regulatory factor) | protein interactions | 10974 | 9 | 6 | 19454 | 5460 |
TOP3B,MIF,IL18,COX17,LYPLA2,ACP2 |
| 1.807e-02 | -4.01 | KCNG3 (potassium voltage-gated channel modifier subfamily G member 3) | protein interactions | 170850 | 9 | 6 | 19454 | 5460 |
KCNB1,KCNF1,VIRMA,KCNG3,KCNC1,DDX39A |
| 1.807e-02 | -4.01 | AMT (aminomethyltransferase) | protein interactions | 275 | 9 | 6 | 19454 | 5460 |
SPPL3,PSMA2,VAC14,HSPA8,RIGI,PDLIM4 |
| 1.807e-02 | -4.01 | GABRB2 (gamma-aminobutyric acid type A receptor subunit beta2) | protein interactions | 2561 | 9 | 6 | 19454 | 5460 |
GABRB3,TP53,PRKCB,GABRA1,PPP3CA,TRAK2 |
| 1.807e-02 | -4.01 | ANO1 (anoctamin 1) | protein interactions | 55107 | 9 | 6 | 19454 | 5460 |
TRIM21,EWSR1,H2BC9,DVL2,LGALS3,TRIM23 |
| 1.807e-02 | -4.01 | PRRT4 (proline rich transmembrane protein 4) | protein interactions | 401399 | 9 | 6 | 19454 | 5460 |
KRAS,LAMP3,TOP3B,LAMP2,RAB2A,RAB5C |
| 1.807e-02 | -4.01 | STEAP2 (STEAP2 metalloreductase) | protein interactions | 261729 | 9 | 6 | 19454 | 5460 |
CTXN1,LAMP3,HNRNPL,PARM1,DPEP1,NDUFA4 |
| 1.807e-02 | -4.01 | Ppp1r10 (protein phosphatase 1, regulatory subunit 10) | protein interactions | 52040 | 9 | 6 | 19454 | 5460 |
PPP1R10,PPP1R2,TOX4,PPP1CC,PPP1CB,WDR82 |
| 1.807e-02 | -4.01 | ACKR1 (atypical chemokine receptor 1 (Duffy blood group)) | protein interactions | 2532 | 9 | 6 | 19454 | 5460 |
CXCL1,CCL5,CXCL8,CCL2,CCL8,CCL17 |
| 1.807e-02 | -4.01 | ZC3H6 (zinc finger CCCH-type containing 6) | protein interactions | 376940 | 9 | 6 | 19454 | 5460 |
GSK3A,ASB8,UBE2L3,VIRMA,SNX3,PRNP |
| 1.807e-02 | -4.01 | ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2) | protein interactions | 432369 | 9 | 6 | 19454 | 5460 |
CAV2,YAF2,NUP35,MAP1LC3B,OPTN,MYC |
| 1.807e-02 | -4.01 | STEAP4 (STEAP4 metalloreductase) | protein interactions | 79689 | 9 | 6 | 19454 | 5460 |
CHMP4C,H1-1,AGPAT1,TP53,AKT2,TERT |
| 1.807e-02 | -4.01 | ORF16 (ORF16) | protein interactions | 4961447 | 9 | 6 | 19454 | 5460 |
GOLPH3L,KLHL22,ZNF622,KLHL9,CUL3,NOP53 |
| 1.807e-02 | -4.01 | KLRA1P (killer cell lectin like receptor A1, pseudogene) | protein interactions | 10748 | 9 | 6 | 19454 | 5460 |
TYROBP,LRFN3,SYK,ST7,LRP12,FZD6 |
| 1.807e-02 | -4.01 | TMC1 (transmembrane channel like 1) | protein interactions | 117531 | 9 | 6 | 19454 | 5460 |
DCAF4,KRAS,CAND1,CIB2,COPS5,H2BC9 |
| 1.807e-02 | -4.01 | ANO3 (anoctamin 3) | protein interactions | 63982 | 9 | 6 | 19454 | 5460 |
SNX3,FBXO22,ASPM,HAPSTR1,HSPA5,RGMA |
| 1.807e-02 | -4.01 | Vcp (valosin containing protein) | protein interactions | 269523 | 9 | 6 | 19454 | 5460 |
CAV1,DERL1,PTEN,UFD1,PTP4A2,CCNF |
| 1.807e-02 | -4.01 | VCX2 (variable charge X-linked 2) | protein interactions | 51480 | 9 | 6 | 19454 | 5460 |
ZNF526,STAC3,DDIT4L,THAP1,PAX6,MACROH2A1 |
| 1.808e-02 | -4.01 | C-MYC pathway | Pathway Interaction DB | myc_pathway | 22 | 13 | 2226 | 782 |
RUVBL2,MYC,SUPT3H,ACTL6A,HBP1,RUVBL1,SUPT7L,TAF9,PAK2,TAF10,ZBTB17,PPP2R5A,MAX |
| 1.808e-02 | -4.01 | PDGFR-alpha signaling pathway | Pathway Interaction DB | pdgfrapathway | 22 | 13 | 2226 | 782 |
CSNK2A1,CRKL,CAV1,JUN,IFNG,ELK1,ITGAV,PIK3R1,JAK1,PIK3CA,SHC1,FOS,CAV3 |
| 1.810e-02 | -4.01 | positive regulation of chemokine production | biological process | GO:0032722 | 72 | 30 | 18204 | 5365 |
TNF,IL17F,ADIPOQ,TLR7,TICAM1,EGR1,TLR3,DEFB124,MAVS,IFNG,TIRAP,TRIM32,IL6,CLEC7A,IL7,OAS1,SELENOK,SYK,TLR9,HMGB1,IL18,MIF,TLR2,EIF2AK2,MYD88,IL1B,AIF1,AGER,PYCARD,TLR4 |
| 1.817e-02 | -4.01 | DSRM | smart domains | SM00358 | 17 | 9 | 9717 | 2575 |
NKRF,STAU1,DROSHA,STRBP,DHX9,EIF2AK2,DGCR8,DICER1,PRKRA |
| 1.817e-02 | -4.01 | maintenance of location in cell | biological process | GO:0051651 | 98 | 39 | 18204 | 5365 |
OS9,RIT2,GPAA1,CALR,PML,HSP90B1,TMSB4X,TBCCD1,ARL2BP,CAV1,RER1,FTL,PAFAH1B1,HEXB,SRI,SUPT7L,FTH1,ARHGAP21,ASPM,TXN,TMSB10,KDELR2,HEXA,KDELR1,CDK5,PGR,AKT1,HSPA5,SRGN,TSPO,FKRP,INSIG2,PSEN1,CD4,SKP1,S100A8,FTHL17,TOPORS,PDIA2 |
| 1.825e-02 | -4.00 | Photodynamic therapy-induced HIF-1 survival signaling | WikiPathways | WP3614 | 37 | 20 | 5310 | 1910 |
VEGFA,LDHA,BNIP3L,BAX,ANGPT1,PGK1,SLC16A1,TP53,MCL1,BCL2L1,BIRC5,BCL2A1,TGFB3,PMAIP1,SLC2A3,EPO,SLC2A1,PDHA1,IGFBP3,BAK1 |
| 1.828e-02 | -4.00 | Signaling events mediated by Stem cell factor receptor (c-Kit) | Pathway Interaction DB | kitpathway | 52 | 26 | 2226 | 782 |
CBL,MITF,BAD,CREBBP,GRAP2,STAT1,MAP2K1,STAP1,PTPN11,JAK2,PIK3CA,PTEN,SHC1,KIT,SNAI2,CRKL,AKT1,EPO,GRB10,GAB1,SPRED1,HRAS,SPRED2,PIK3R1,STAT5A,RAF1 |
| 1.828e-02 | -4.00 | HAPSTR1 (HUWE1 associated protein modifying stress responses) | protein interactions | 29035 | 544 | 175 | 19454 | 5460 |
ACAP2,ALG5,ATP5F1B,ADH1B,SF3B4,TRIB1,CCT2,PSMD1,CCL24,RUSC2,SSR3,UFL1,MED13L,CREG2,MORN4,SHMT1,FBXO42,NUP62,CCT7,CYTH4,RHOH,TCP1,MAGED2,DRG1,DIS3L,XPO1,DNTTIP1,NDUFV2,RAB5C,RERE,PRPS1,PSMA1,KRAS,CCT8,RPL18,ZRANB2,MTA2,LSM10,PLS3,KIF2A,ELF1,DIRAS1,ROCK1,LYPD6,INTS12,PSMC5,RPS3,ZBTB38,IGF2BP1,PDCD4,LSM6,ANO3,GSTK1,SPRED1,SLC25A27,BCL2A1,MARS1,GRPEL1,DLAT,HSPB2,TRIM10,BAP1,SEPTIN6,UBE2M,HEXIM1,SURF6,CD99L2,PHYH,CAND1,RPS16,GATAD1,ADD1,USP15,TSNAX,TNFRSF14,AKAP8L,CHCHD1,SLITRK5,PPM1D,ADIPOR2,STX11,SMIM11,CSE1L,KPNA2,GRAP2,CBX3,EXOC3,ZMYM4,EMILIN3,IPO8,SRFBP1,PLA2G5,GNB1,PRRC2A,CHCHD3,UBE2V2,TAB1,ARF1,TRIQK,MCM4,ALDH1L1,PSMC1,PPP2R3A,HADHA,C1D,TERT,NEUROG2,ADNP,USP39,SOX21,DHX15,BRD9,XPO5,KLHL7,SLC20A1,ZNF175,MED4,TMEM164,HAX1,AHSA1,PSMD10,DDX23,WDR11,FAM181B,FAM174A,RPS27A,PSMD12,ASF1A,KCTD17,PLCB1,ARGLU1,PPP2R1A,NUP153,MAK16,NAA15,ANP32A,ANKH,ZBTB17,GNPDA1,LURAP1,XPOT,IVNS1ABP,KPNA6,SKAP2,GMPS,ATP5F1A,SEC13,EIF5B,GTF2I,H2BC12,ANAPC16,VIP,IFRD1,PICALM,DCTN4,CCN3,ATP6V0E1,SF3A1,PCK2,POLE3,RB1,NAA30,IRF4,PTGES3,EIF3E,NSMCE3,HUWE1,CTNNBL1,SEMG2,HAPSTR1,RING1,TTPAL,GPR34,YTHDF2,CCT5 |
| 1.828e-02 | -4.00 | POM121 (POM121 transmembrane nucleoporin) | protein interactions | 9883 | 146 | 53 | 19454 | 5460 |
MANSC1,SNRNP40,OTUD6A,DYRK1A,B4GAT1,CCNF,LMBR1L,NFKBIA,FBLN5,CLDN3,TRIM27,DKK3,SEC61B,HFE,BRCA1,LMNB1,CGRRF1,TRIM23,KPNA6,FXR2,G3BP2,TSPAN15,GRIA2,FAM168B,NUP50,LMNA,WRAP53,CHRNB2,TFIP11,LPXN,PRMT2,CCL3,FMOD,NUP35,KCNA2,HOMER3,BOLL,SPINT2,AGR2,AHSA1,KPNA2,LRP3,TMED7,LTBR,BSCL2,FHL3,CTLA4,SFTPC,IL20RB,JPH4,TRAF2,CTDSP2,NUP153 |
| 1.828e-02 | -4.00 | SPCS1 (signal peptidase complex subunit 1) | protein interactions | 28972 | 146 | 53 | 19454 | 5460 |
AQP2,RHOG,SLC25A46,EMC4,RAC2,RPRM,SSMEM1,ALPL,CRELD1,NRN1,RP9,MOXD1,WBP11,SLC29A1,CCDC47,SRFBP1,TP53,KRAS,DHX16,IGF1,EMC2,SEC11A,FIS1,SPCS3,RBM27,BRCA1,MBLAC2,RIOK2,GMNN,TM2D2,TMED4,PRRC2A,COPE,DNASE1L1,TMEM74,GTF2F2,GTF2F1,FBXL14,CYB5R3,GPC4,OTULINL,SNRNP27,TOMM22,SLC19A2,TSPAN5,HSPA5,EMC1,GPC1,SYVN1,MTDH,SPCS2,DDX46,TMEM106B |
| 1.830e-02 | -4.00 | positive regulation of cell migration involved in sprouting angiogenesis | biological process | GO:0090050 | 36 | 17 | 18204 | 5365 |
RHOJ,NRP1,MIR31,AKT3,MIR132,MIR101-1,MAP3K3,VEGFA,MIR126,FOXC2,MIR10A,MIR296,MIR10B,MIR146A,FGFBP1,MIR23A,MIR150 |
| 1.830e-02 | -4.00 | regulation of response to oxidative stress | biological process | GO:1902882 | 36 | 17 | 18204 | 5365 |
MACROH2A1,MIR132,SESN2,NFE2L2,FADS2,SLC7A11,FBLN5,SLC25A14,MIR21,GGT7,SELENON,PNPLA8,HDAC6,FUT8,CD36,SESN3,TBC1D24 |
| 1.830e-02 | -4.00 | nucleotide-sugar metabolic process | biological process | GO:0009225 | 36 | 17 | 18204 | 5365 |
UAP1,EXTL2,GNPNAT1,FUT8,UGDH,GFUS,MGAT1,GMPPB,DPAGT1,CSGALNACT1,GMDS,GFPT1,GNPDA1,UGP2,GNPDA2,PMM2,GUK1 |
| 1.830e-02 | -4.00 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | biological process | GO:0043162 | 36 | 17 | 18204 | 5365 |
CHMP2A,TSG101,UBAP1,VPS28,CHMP1B,CHMP5,VPS4B,HGS,PLAA,TOM1L1,HDAC6,CHMP2B,CHMP4C,VPS4A,RNF115,CHMP1A,RNF126 |
| 1.830e-02 | -4.00 | behavioral defense response | biological process | GO:0002209 | 36 | 17 | 18204 | 5365 |
NR2E1,EP300,BRINP1,COMT,HTR1A,USP46,LARGE1,MECP2,VDAC1,DPP4,SLC1A1,EIF4E,ASIC1,NEUROD2,DRD1,GNG7,ATP1A2 |
| 1.830e-02 | -4.00 | negative regulation of interleukin-8 production | biological process | GO:0032717 | 36 | 17 | 18204 | 5365 |
MIR146A,OTUD7B,MIR488,MIR920,TLR6,MIRLET7C,MIR129-1,ANXA4,MIR98,KLF4,IL10,MIR106A,MIR204,MIR132,PTPN22,MIR100,MIR106B |
| 1.830e-02 | -4.00 | late endosome to vacuole transport | biological process | GO:0045324 | 36 | 17 | 18204 | 5365 |
CHMP1A,VPS4A,CHMP4C,CHMP2B,HGS,BECN1,VPS4B,CHMP5,TMEM50B,CHMP1B,VPS28,UBAP1,TSG101,CHMP2A,VTA1,TMEM50A,LEPROTL1 |
| 1.833e-02 | -4.00 | NCKIPSD (NCK interacting protein with SH3 domain) | protein interactions | 51517 | 118 | 44 | 19454 | 5460 |
ESR2,LRIF1,DYNLL1,DAPK1,DLG4,CTTN,GEMIN8,YWHAZ,TSEN54,RBM15B,ATP5F1A,PRPF31,COPS7A,AKT1,HSPA5,RBM22,SNX33,ARHGEF6,CSNK1A1,RARS1,GIT2,HSP90AB1,CNTROB,PRNP,COPS7B,COPS2,WDR6,HSPB1,YWHAB,ARMC8,NCK1,ACTR3B,YWHAH,XPO1,COPS5,YWHAG,ENKD1,COPS4,CPNE2,PSORS1C2,ACTR2,CAPZA2,JUN,FASLG |
| 1.833e-02 | -4.00 | TDRD3 (tudor domain containing 3) | protein interactions | 81550 | 203 | 71 | 19454 | 5460 |
SYNCRIP,FUBP3,PAIP1,FAM98A,THOC1,DHX15,GRSF1,MOV10,CNOT2,HNRNPA1,STK4,TDRD7,SSX2IP,DDX1,LYZ,DNAJC7,MAGOH,PABPC1,LSM14A,GARRE1,EWSR1,ZC3H7A,POC1B,DHX9,RTCB,BAG2,RPS24,CNOT7,LSM4,G3BP1,RPL28,TOP3B,E2F4,YTHDF2,EEF1A1,GLE1,GTPBP1,STUB1,SMAP2,EIF4A3,RTRAF,GSK3A,RPS20,EIF4A2,ESR2,PRRC2A,APEX1,MLF1,H2BC9,TIA1,ST13,ASCC1,RC3H2,DCAF4,IGF2BP1,PAIP2,LSM14B,CASC3,MAPRE1,LCA5,LSM12,SQSTM1,SMG5,FXR2,STAU1,YTHDF1,G3BP2,AGO1,LARP4B,NUFIP2,TRIM36 |
| 1.833e-02 | -4.00 | late endosome | cellular component | GO:0005770 | 312 | 108 | 19108 | 5553 |
LAMTOR1,SLA2,RNF128,HDAC6,MREG,SLC1A1,IL12A,VPS16,CHMP5,AP5S1,AP1AR,PLD3,STX8,CHMP2B,TMEM30A,CHMP1B,ZMPSTE24,LDLR,SRC,SLC38A9,B2M,VPS18,CRHBP,VAMP7,CD63,EXOC8,CHID1,CLCN6,RAB27A,TMEM59,PIP4P2,TICAM2,TSG101,FIG4,VTI1B,ATG9A,CHMP1A,CD2AP,CDIP1,CHMP4C,RAB9A,RAB22A,LAMTOR2,LRAT,CHMP2A,MCOLN1,RNF133,IL12B,PGA4,HSPA8,MMD,LAMP3,RAP1A,PCSK9,BACE1,LAPTM4A,VPS4A,DERL1,VIPAS39,VPS39,MBL2,VAC14,BST2,RAB14,AP5M1,LITAF,RHOB,LAMTOR3,ABHD6,STX7,VPS28,SNX14,SLC11A2,LAMP5,RAB11A,VTA1,SLC31A1,TSPAN15,PARM1,UBXN6,DDIT3,NSG1,CD1E,MAP2K1,LAMP2,VAMP8,PIP4P1,TMEM106B,DERL2,MAP1LC3A,CXCR4,GOSR2,VPS4B,SQSTM1,VPS26B,TF,RAB9B,SFTPA1,STARD3NL,HGS,SFTPD,RNF148,SFTPC,TPT1,VAMP5,IFNAR1,VPS33A,MTM1 |
| 1.840e-02 | -4.00 | hormone metabolic process | biological process | GO:0042445 | 206 | 75 | 18204 | 5365 |
AANAT,CTSK,RDH12,DIO1,HSD17B10,DHRS7,DIO3,LHB,CHST9,CYP17A1,ASMT,HSD17B11,CHST10,CYP11B2,HSD17B8,LEP,DHRS3,UGT2A3,PTPN11,SULT1B1,ADH1B,HSD17B6,AKR1B1,RETSAT,PCSK2,SPP1,ATP6AP2,HFE,GHR,KLK6,RDH11,SCG5,REN,UGT1A1,CRABP2,MME,CYP3A5,CYP26A1,SELENOM,DIO2,HSD17B3,CYP11B1,SCPEP1,CYP2C18,RDH10,CMA1,SLC16A10,SDR16C5,FURIN,CTSB,CYP2C9,LRAT,PNPLA4,AKR1C1,DHRS11,AKR1C2,CYP2C8,HSD17B1,CYP1A1,CRYM,SRD5A3,CYP21A2,PAPSS2,IDE,DHRS4,DPP4,ENPEP,YIPF5,ALDH1A3,CYP1B1,ADH1A,SLC30A5,CPE,CYP2D6,TSPO |
| 1.842e-02 | -3.99 | regulation of endothelial cell development | biological process | GO:1901550 | 18 | 10 | 18204 | 5365 |
PLCB1,ROCK1,PPP1R12A,ADD1,TNF,F11R,VEGFA,IKBKB,ROCK2,IL1B |
| 1.842e-02 | -3.99 | regulation of telomerase RNA localization to Cajal body | biological process | GO:1904872 | 18 | 10 | 18204 | 5365 |
NHP2,DKC1,TCP1,CCT2,DCP2,CCT5,CCT7,RUVBL1,CCT8,RUVBL2 |
| 1.842e-02 | -3.99 | regulation of establishment of endothelial barrier | biological process | GO:1903140 | 18 | 10 | 18204 | 5365 |
IL1B,ROCK2,IKBKB,VEGFA,F11R,TNF,ADD1,PPP1R12A,ROCK1,PLCB1 |
| 1.842e-02 | -3.99 | angiogenesis involved in wound healing | biological process | GO:0060055 | 18 | 10 | 18204 | 5365 |
GPX1,ADIPOR2,CD34,NDNF,CX3CL1,B4GALT1,DAG1,VEGFA,PRCP,NPR2 |
| 1.842e-02 | -3.99 | positive regulation of neuroinflammatory response | biological process | GO:0150078 | 18 | 10 | 18204 | 5365 |
CCL3,TNF,IL18,IL6,MIR206,CTSC,IL1B,MIR142,NUPR1,STAP1 |
| 1.847e-02 | -3.99 | PXN (paxillin) | protein interactions | 5829 | 326 | 109 | 19454 | 5460 |
CTNNB1,XPO1,ISX,DPY30,PIK3R1,HSPB1,CBL,CDC23,RASSF8,NCK1,ARHGAP5,ELP6,MAP1LC3A,IGBP1,SDC4,CNTROB,TRIM15,DYNC1I2,ACO1,TOP3B,RAF1,B3GNT2,CRKL,BAG2,PRPSAP1,RABGGTB,PABPC1,ZYX,SCYL2,SLC25A5,PRPS1,RAB8B,BAG3,GALE,MRPL16,CUL3,PYCR1,USP13,ILK,NLRP3,PHF21A,RAN,ARF1,ESR2,DYNLL1,MRPL23,MRPL12,LMO3,SYK,NUP62,SLC25A3,CSNK1A1,MAP2K1,PAK2,HSPA8,RPS28,TGFB1I1,ITGAV,STAU1,RNF5,HDAC6,MOV10,SHC1,TUBG1,DSTN,WDCP,ITGA6,EXOSC8,IPO8,TP53,TBK1,IGF1R,SLC25A11,TMEM33,WASL,H3C1,AR,ATP5F1A,PTPN11,CDC16,CSK,IVNS1ABP,BICD2,PTEN,GSK3A,WDR45,TUBA1B,CTTN,SRC,CEP97,ROCK1,FERMT2,CHMP5,YES1,COPE,POLR1D,GIT2,PICALM,RNF146,JUP,CSNK1A1L,SQSTM1,PML,ARHGEF6,DVL2,RHOU,HSPA5,NF2,KDM1A |
| 1.854e-02 | -3.99 | interleukin-1-mediated signaling pathway | biological process | GO:0070498 | 23 | 12 | 18204 | 5365 |
IRAK4,IL1B,RPS6KA4,EGR1,MYD88,TRAF6,IKBKB,TOLLIP,PLCB1,NFKBIA,MIR146A,IL1RAP |
| 1.854e-02 | -3.99 | endolysosomal toll-like receptor signaling pathway | biological process | GO:0140894 | 23 | 12 | 18204 | 5365 |
TLR8,PIK3AP1,OAS1,TLR9,TNF,TLR7,TICAM1,TRAF6,IKBKB,MYD88,TLR3,IRAK4 |
| 1.854e-02 | -3.99 | mitochondrial fusion | biological process | GO:0008053 | 23 | 12 | 18204 | 5365 |
MIEF1,USP30,CHCHD3,PARL,FIS1,BAK1,BAX,MFN1,MCL1,BCL2A1,STOML2,THG1L |
| 1.854e-02 | -3.99 | protein peptidyl-prolyl isomerization | biological process | GO:0000413 | 23 | 12 | 18204 | 5365 |
FKBP1B,PPWD1,PPIH,FKBP1A,PPIL3,PPIC,PPIA,PPIG,FKBP4,PPID,PPIF,PPIB |
| 1.854e-02 | -3.99 | cellular response to lectin | biological process | GO:1990858 | 23 | 12 | 18204 | 5365 |
SYK,KLRC2,EP300,TYROBP,PAK2,CLEC7A,KLRD1,SRC,CLEC6A,TRAF6,CREBBP,IKBKB |
| 1.854e-02 | -3.99 | negative regulation of nucleocytoplasmic transport | biological process | GO:0046823 | 23 | 12 | 18204 | 5365 |
SUMO1,UFM1,PKIA,NUP153,CD36,TXN,CHP1,SUFU,ANGPT1,CDK5,PKIG,RAB23 |
| 1.854e-02 | -3.99 | response to lectin | biological process | GO:1990840 | 23 | 12 | 18204 | 5365 |
SRC,CLEC6A,IKBKB,TRAF6,TYROBP,EP300,SYK,CREBBP,KLRD1,CLEC7A,PAK2,KLRC2 |
| 1.854e-02 | -3.99 | amyloid precursor protein metabolic process | biological process | GO:0042982 | 23 | 12 | 18204 | 5365 |
TMCC2,DLG1,PSEN1,PSEN2,BACE1,NCSTN,KLK6,DYRK1A,NSG1,ACHE,APH1A,PSENEN |
| 1.854e-02 | -3.99 | negative regulation of oxidoreductase activity | biological process | GO:0051354 | 23 | 12 | 18204 | 5365 |
MIR130B,NFKB1,HDAC6,HP,MIR378A,MIR21,MT3,CAV3,ATP2B4,NOSIP,GFI1,CYP27B1 |
| 1.854e-02 | -3.99 | negative regulation of leukocyte chemotaxis | biological process | GO:0002689 | 23 | 12 | 18204 | 5365 |
TNFAIP6,CCN3,DPP4,DUSP1,GREM1,STAP1,PADI2,MIF,CCL2,MIR223,MMP28,DDT |
| 1.854e-02 | -3.99 | negative regulation of systemic arterial blood pressure | biological process | GO:0003085 | 23 | 12 | 18204 | 5365 |
ADRB1,PRCP,MIR17,IER3,TNF,BMPR2,ADRB3,GPR37L1,ADRB2,ADORA1,ADRA1A,SOD2 |
| 1.854e-02 | -3.99 | stimulatory C-type lectin receptor signaling pathway | biological process | GO:0002223 | 23 | 12 | 18204 | 5365 |
TYROBP,SYK,EP300,SRC,CLEC6A,TRAF6,IKBKB,PAK2,CLEC7A,KLRC2,KLRD1,CREBBP |
| 1.855e-02 | -3.99 | ZNHIT3 (zinc finger HIT-type containing 3) | protein interactions | 9326 | 49 | 21 | 19454 | 5460 |
HECTD1,NUFIP2,FCMR,ZNHIT3,RC3H2,PPARG,RBMS2,ANAPC15,XPO1,PRPF31,ZCCHC10,ZNF24,PRPF19,MOV10,MAX,APEX1,ESR2,RUVBL1,NOP58,RALA,ZNHIT6 |
| 1.855e-02 | -3.99 | TSPYL5 (TSPY like 5) | protein interactions | 85453 | 49 | 21 | 19454 | 5460 |
HP1BP3,RNF113A,MACROH2A1,FAM76B,HSPA8,RPL23A,TUBA1B,RPL31,RPL8,ESR2,MEPCE,STAU1,TOP1,H3C1,RPL15,NONO,ISG15,WWP2,MYC,NUFIP2,H2AC4 |
| 1.855e-02 | -3.99 | SFXN5 (sideroflexin 5) | protein interactions | 94097 | 49 | 21 | 19454 | 5460 |
SLC5A6,TMEM237,APLNR,ACTB,SLC15A1,TNF,CD80,TMEM108,SLC22A6,SLC39A9,CXCR4,PRKAG1,STOM,CTSA,AQP3,FAS,ATP1A3,TOMM40,LPAR6,MICB,LAMP2 |
| 1.855e-02 | -3.99 | NLN (neurolysin) | protein interactions | 57486 | 49 | 21 | 19454 | 5460 |
SPPL3,HSCB,DYNLL1,OLA1,FPGT,RPA3,DLST,HSPA8,KRT8,TES,SDHAF4,CAMK1,PDHA1,GNPDA2,ACOT13,ZNF526,RASSF8,LEMD3,PGAM1,MRPL9,ELP3 |
| 1.855e-02 | -3.99 | BPNT2 (3'(2'), 5'-bisphosphate nucleotidase 2) | protein interactions | 54928 | 49 | 21 | 19454 | 5460 |
UST,UQCC3,RAB39B,EFNA5,VIRMA,TOMM6,OCRL,MLH3,LCN9,CLEC12B,CD1B,ST8SIA4,SEC61B,CYB5R3,ST3GAL4,ATP1B3,CSGALNACT2,DDRGK1,GOLPH3L,TPT1,FAM20C |
| 1.855e-02 | -3.99 | TRIM50 (tripartite motif containing 50) | protein interactions | 135892 | 49 | 21 | 19454 | 5460 |
UBE2D3,UBE2K,PRNP,UBTD1,SRC,UBE2N,TRIM27,SQSTM1,GCC1,UBE2D1,BECN1,UBE2E3,NLRP3,XAF1,UBE2E2,USP2,TRAF2,HDAC6,SPG21,NEK7,TULP3 |
| 1.858e-02 | -3.99 | LRRC25 (leucine rich repeat containing 25) | protein interactions | 126364 | 184 | 65 | 19454 | 5460 |
PEX3,CLEC1A,FATE1,IQSEC1,ANKRD46,SPPL3,CXCL9,MSMO1,SLC25A12,GLT8D1,RAB35,DEFB121,TRAF3IP3,CETN3,EXOC3,SEC61G,SLC25A20,DHRS7B,ARFGEF1,ALG11,ISG15,TUBA1A,TNPO2,AGPAT5,DCP2,TNF,RAB3B,DNAJC30,AP1M1,FASTKD5,SLC25A14,RIGI,RAB13,SLC39A3,ATP1A3,GGCX,VMP1,TMEM38B,VAMP5,OPRM1,TMEM183A,NCAPG2,RHOBTB3,IP6K1,SLC25A4,LGALS3,CLRN2,ALG5,ODR4,SFXN2,SMCO4,LMBRD2,GHITM,TTI2,FAM3C,TOMM22,EDDM3B,SEC22A,KDELR2,DAD1,SLC5A6,ATP2C1,RAB29,FLCN,COMMD2 |
| 1.858e-02 | -3.99 | DAZAP2 (DAZ associated protein 2) | protein interactions | 9802 | 184 | 65 | 19454 | 5460 |
UBA52,PRR13,PLSCR4,RBFOX2,KRTAP8-1,WWP1,MED31,NDUFA5,STAT6,SQSTM1,RAMAC,MYOZ3,DESI1,LITAF,AATF,LMO2,USP13,BAG3,CEP70,RUNX1,OTUD7B,UBE2E3,FAM83A,SMAP2,RNF208,ATXN1L,OPTN,UBASH3B,RETREG3,TAX1BP1,TENT5C,SIAH1,USP5,UBB,TP53,CDK4,GDE1,UBE2V1,ZNF581,MINDY3,OTULIN,HGS,ZFAND2A,BHLHE40,PLSCR1,UBE3A,FAM168A,TOM1,MAPK1IP1L,TOLLIP,NOC4L,RNF115,LASP1,TFG,PDE2A,RPS27A,CXCL12,TLE1,UBE2E2,UBXN6,CTNNB1,ZFAND2B,SPMIP9,PLEKHF2,DCUN1D1 |
| 1.858e-02 | -3.99 | CFL2 (cofilin 2) | protein interactions | 1073 | 115 | 43 | 19454 | 5460 |
EZH2,PIR,CAPZA2,HEXIM1,SOD2,SH3GLB2,NUPR1,COMMD3,PPP1CB,CDC42,MEPCE,PSMB10,SOD1,BAP1,NME2,STK11,NQO1,MOV10,RAB2A,CRIP1,DPP4,CAP2,LDHB,CFL2,PDE4B,HNRNPA1,CD81,CFL1,ACP6,USP14,ST13,DAPK1,LDHA,DAPK3,ACTB,SUCLG2,MAD2L2,DYRK1A,APEX1,CTTN,DSTN,UBE2I,AKR1B1 |
| 1.859e-02 | -3.98 | PLP | smart domains | SM00002 | 3 | 3 | 9717 | 2575 |
PLP1,GPM6A,GPM6B |
| 1.859e-02 | -3.98 | FDF | smart domains | SM01199 | 3 | 3 | 9717 | 2575 |
EDC3,LSM14B,LSM14A |
| 1.859e-02 | -3.98 | LSM14 | smart domains | SM01271 | 3 | 3 | 9717 | 2575 |
EDC3,LSM14B,LSM14A |
| 1.861e-02 | -3.98 | tumor necrosis factor receptor superfamily binding | molecular function | GO:0032813 | 49 | 22 | 18094 | 5411 |
TMBIM1,NTF4,TNF,TNFSF12,LTA,MYD88,SIVA1,FASLG,TRIM37,TNFSF8,FEM1B,TNFSF15,TRAF2,TNFSF18,TRAF1,STAT1,CD40LG,LTB,TNFSF13,TRAF6,TNFSF10,BEX3 |
| 1.862e-02 | -3.98 | OSGEP (O-sialoglycoprotein endopeptidase) | protein interactions | 55644 | 143 | 52 | 19454 | 5460 |
HSPA5,GON7,NMRAL1,RPA3,EPHX1,MAP2K1,IDH2,HPS6,RPRD1B,P3H1,RPA2,CFTR,POLR1D,EHD1,NFYB,TOM1L1,TAX1BP1,RAB14,F11R,CYRIB,POP7,LMBR1L,CALU,UBE2H,OSGEP,IRF6,STK24,NIF3L1,CUL2,PKP4,SPRED1,NAA50,VRK1,KRAS,HNRNPF,UFM1,VPS26B,CASTOR2,PPP1R12A,ILF2,ACTR2,RAP1A,CYTH4,ALCAM,TES,WDR82,NAP1L5,SHC1,PPM1B,ELOC,API5,RAB5C |
| 1.862e-02 | -3.98 | PARN (poly(A)-specific ribonuclease) | protein interactions | 5073 | 143 | 52 | 19454 | 5460 |
EXOSC4,TXNL1,UPF3B,SIRT7,RPA3,MCMBP,B9D2,SRSF2,MND1,RPL27A,RPL26L1,RPA2,LMNA,PALS2,ZNF330,DLST,EIF4A3,DOK4,DYRK1A,CSTF3,MED17,TAX1BP1,SSH3,RNF40,MYC,UBE2H,H1-1,RPS24,RPL23A,RPL31,MDC1,RPS13,H3C1,TULP3,ESS2,KIAA0408,TP53,RPS11,PDHA1,LDLR,PRR3,RBM5,KRR1,SURF6,SUMO2,RPS16,CSNK2A1,MPHOSPH6,PPP3CA,H2AC4,ANKRD49,DDX23 |
| 1.862e-02 | -3.98 | FAM168A (family with sequence similarity 168 member A) | protein interactions | 23201 | 143 | 52 | 19454 | 5460 |
BOLL,POLR2L,EGLN3,DCUN1D1,HNRNPL,POLR2I,UBXN6,MOV10,WWP2,HR,BABAM1,FBXO11,EWSR1,FAM168A,PLSCR1,ALKBH4,RPS27A,TFG,LASP1,TOLLIP,RPAP2,UBE2V1,POLR2G,POLR2C,POLR2D,OTULIN,SART3,HGS,LRP12,UBASH3B,SMAP2,KRTAP3-1,ATXN1L,UBB,POLR2B,VIRMA,ESR2,TAX1BP1,NDFIP1,OTUD7B,BAG3,AKT1,MYC,SMARCD3,DVL2,WBP2,FAM168B,YTHDF1,KRTAP8-1,USP6NL,UBA52,WWP1 |
| 1.862e-02 | -3.98 | TBX2 (T-box transcription factor 2) | protein interactions | 6909 | 24 | 12 | 19454 | 5460 |
PML,ATXN1L,RNF113A,CEBPE,EGR1,LMO2,CNOT2,CIDEB,TNPO2,DDX39A,SOX2,KLF3 |
| 1.862e-02 | -3.98 | NRXN3 (neurexin 3) | protein interactions | 9369 | 24 | 12 | 19454 | 5460 |
HADHA,NLGN1,NLGN2,KRAS,CAMKV,TAFA1,DNAJC5,CBLN4,MYC,PIP5K1A,CASK,LRRTM3 |
| 1.862e-02 | -3.98 | Pqbp1 (polyglutamine binding protein 1) | protein interactions | 54633 | 24 | 12 | 19454 | 5460 |
IK,LSM6,MFAP1,TOPORS,CFAP20,UBL5,PRPF31,WBP11,RBM22,SNRNP40,PRPF4,SMU1 |
| 1.862e-02 | -3.98 | FAM13B (family with sequence similarity 13 member B) | protein interactions | 51306 | 24 | 12 | 19454 | 5460 |
SEC61B,RIGI,AHCYL1,CHCHD3,QPCTL,PPP2R1A,YWHAG,CDC42,SAMHD1,HAX1,YWHAZ,RPN1 |
| 1.862e-02 | -3.98 | TMEM102 (transmembrane protein 102) | protein interactions | 284114 | 24 | 12 | 19454 | 5460 |
TRAPPC4,TRAPPC2L,YWHAZ,YWHAH,TRAF2,YWHAG,RAB11A,VIRMA,MB21D2,TRAPPC3,TRAPPC10,TRAPPC1 |
| 1.862e-02 | -3.98 | P2RX1 (purinergic receptor P2X 1) | protein interactions | 5023 | 24 | 12 | 19454 | 5460 |
ATP1A3,ARMCX3,FDFT1,FAM20B,GOLPH3L,COA1,ASIC1,ATP2C1,HSPD1,ARL10,CYBC1,SEC11A |
| 1.862e-02 | -3.98 | ZNF639 (zinc finger protein 639) | protein interactions | 51193 | 24 | 12 | 19454 | 5460 |
PRPF18,ZBTB2,RBBP4,MPP1,RASSF8,APTX,ELP6,NTAQ1,CTNNB1,ZNF250,CREBBP,CSK |
| 1.862e-02 | -3.98 | PMCH (pro-melanin concentrating hormone) | protein interactions | 5367 | 24 | 12 | 19454 | 5460 |
MCHR1,TPST1,MAEA,NPW,SERPINC1,PCSK2,CPE,FURIN,MCHR2,TMEM59,CDKN2D,NPY |
| 1.862e-02 | -3.98 | TAS2R19 (taste 2 receptor member 19) | protein interactions | 259294 | 24 | 12 | 19454 | 5460 |
ATP5F1A,VPS26A,ATP5PB,TMEM14B,GOLGA5,ABCB1,SERINC1,CERS6,CAV1,TMEM167B,ATP5F1D,ATP5F1B |
| 1.862e-02 | -3.98 | HBG2 (hemoglobin subunit gamma 2) | protein interactions | 3048 | 24 | 12 | 19454 | 5460 |
HRAS,CYB5R3,CCNY,XPNPEP1,UBB,SMAD5,SRC,RPSA,HBM,HBA1,HBB,GNAZ |
| 1.862e-02 | -3.98 | PRAG1 (PEAK1 related, kinase-activating pseudokinase 1) | protein interactions | 157285 | 24 | 12 | 19454 | 5460 |
HSP90AA1,CRKL,YWHAH,YWHAG,PPP1CC,TOP3B,CSK,CUL3,ESR2,VIRMA,NAPG,UBE3A |
| 1.862e-02 | -3.98 | GPR84 (G protein-coupled receptor 84) | protein interactions | 53831 | 24 | 12 | 19454 | 5460 |
LGALS3,SIGMAR1,RER1,ECHDC1,COG1,ATP1A3,CERS6,TTI2,RAB29,MPDU1,EI24,TNPO2 |
| 1.862e-02 | -3.98 | SLC35F5 (solute carrier family 35 member F5) | protein interactions | 80255 | 24 | 12 | 19454 | 5460 |
CXCR4,GINM1,KCNA2,YIPF3,TMEM74,SPINT2,CTLA4,CX3CL1,HNRNPL,MANSC1,AVPR1B,SHOC2 |
| 1.862e-02 | -3.98 | TPST1 (tyrosylprotein sulfotransferase 1) | protein interactions | 8460 | 24 | 12 | 19454 | 5460 |
GINM1,CMKLR2,CSGALNACT2,GOLPH3L,CCR1,CCR5,B2M,CCR2,CLEC12B,ACTB,HSPA5,VIRMA |
| 1.863e-02 | -3.98 | syntaxin binding | molecular function | GO:0019905 | 60 | 26 | 18094 | 5411 |
NAPA,VAMP3,SLC6A4,STX8,STX16,STX7,CPLX3,NAPG,VAMP2,RAB11A,VPS54,SCFD1,STXBP1,STX6,DAPK1,VPS18,CPLX2,TMED9,VAMP8,SNAP25,VAMP1,STX10,SNAP23,HECTD3,CPLX1,SNAP29 |
| 1.864e-02 | -3.98 | maternal process involved in female pregnancy | biological process | GO:0060135 | 58 | 25 | 18204 | 5365 |
STOX2,CNR1,AR,PTN,KLF1,GHRL,JUNB,SPP1,RGS2,TPPP3,PGR,NDP,AKT1,VDR,GJB2,KPNA6,BMPR2,DEDD,PRDX3,LDOC1,STC1,PARP2,CTSB,TCF23,CYP27B1 |
| 1.865e-02 | -3.98 | regulation of alpha-beta T cell differentiation | biological process | GO:0046637 | 75 | 31 | 18204 | 5365 |
MIR21,BATF,KLHL25,LILRB4,CCL19,IL2,IRF4,TGFBR2,BCL6,ZBTB16,NLRP3,FOXP3,SYK,JUNB,HMGB1,NKAP,SASH3,IL18,PNP,RUNX1,SOCS5,CD83,CD86,IL2RG,IL23A,CD80,CBFB,IL12B,IFNG,RC3H2,EP300 |
| 1.865e-02 | -3.98 | body fluid secretion | biological process | GO:0007589 | 75 | 31 | 18204 | 5365 |
SOCS2,LACRT,OXTR,TRAF3IP2,FGF10,FOSL2,CREB1,VEGFA,PRKCE,VDR,CHRM3,VAMP2,CHRM1,SLC6A3,CAV1,UPRT,UMPS,STAT5A,VIP,CCND1,SLC29A1,AGR2,VAMP3,ADORA1,VAMP8,APLN,PRL,GJA1,DDR1,CDO1,NME1 |
| 1.865e-02 | -3.98 | Ribosomal_eL8/eL30/eS12/Gad45 | interpro domains | IPR004038 | 11 | 7 | 18521 | 5414 |
RPL7A,SECISBP2L,GADD45B,GADD45G,NHP2,GADD45A,RPS12 |
| 1.865e-02 | -3.98 | AdipoR/HlyIII-related | interpro domains | IPR004254 | 11 | 7 | 18521 | 5414 |
ADIPOR2,MMD,PAQR4,PAQR9,PAQR8,ADIPOR1,PAQR3 |
| 1.865e-02 | -3.98 | transforming growth factor beta receptor signaling pathway | biological process | GO:0007179 | 104 | 41 | 18204 | 5365 |
MIR21,CHST11,SMAD4,MIR30A,SMAD5,TGFBR2,FMOD,FUT8,MIR212,ITGB8,USP15,SRC,SMAD2,MIR183,TGFB3,ACVR1,NDP,ID1,COL3A1,ITGB5,JUN,MSTN,LPXN,CITED1,COL1A2,FERMT2,EID2,ZYX,FLCN,TAB1,SMAD3,PML,BMPR1A,TGFB2,CAV2,TP53,DUSP22,FURIN,SMAD1,SMAD9,FOS |
| 1.877e-02 | -3.98 | Lipocln_cytosolic_FA-bd_dom | interpro domains | IPR000566 | 31 | 15 | 18521 | 5414 |
LCN6,LCN1,LCN8,RBP5,FABP5,FABP7,PAEP,PMP2,FABP4,RBP2,FABP12,LCN15,LCN12,CRABP2,PTGDS |
| 1.883e-02 | -3.97 | ING5 (inhibitor of growth family member 5) | protein interactions | 84289 | 112 | 42 | 19454 | 5460 |
MORF4L1,VAMP5,HMGA1,MOV10,KXD1,MCM4,CCDC85B,SMARCE1,H2BC9,NOS1AP,TADA3,BEX3,NAIF1,ICA1,CCHCR1,VPS72,H2AZ1,CDC7,CSNK2B,PRMT5,MEAF6,CDK9,FAM118B,TP53,CDKN1A,TUBA1A,TAF1D,MAP2K1,CAAP1,DMAP1,HGS,MEST,THAP6,JADE1,EP300,NUCKS1,RUVBL1,OIP5,MCMBP,SSRP1,CDCA7L,MCM6 |
| 1.883e-02 | -3.97 | MAP7D3 (MAP7 domain containing 3) | protein interactions | 79649 | 112 | 42 | 19454 | 5460 |
KBTBD4,KIF2A,TUBA1A,PNMA2,RPA2,TRIM36,RBPJ,S100B,RPA3,LCA5,SQSTM1,ZC3H7A,TRIM37,STAU1,SFN,CDC16,MOV10,PPP1CC,YWHAG,CAV3,YWHAH,HDAC6,YWHAZ,CAMSAP2,YWHAB,MAPRE1,UBE2H,TNNC2,MED4,SSX2IP,ARL10,CCNF,SPINT2,TRAK2,RMDN3,GSK3A,STAT1,RPS10,GSTCD,VIRMA,CBX5,EGLN3 |
| 1.883e-02 | -3.97 | chemokine binding | molecular function | GO:0019956 | 33 | 16 | 18094 | 5411 |
CCR5,CX3CR1,CCR4,CXCR1,CXCR3,CXCR4,CXCR6,CCR6,CCR7,CCR1,PLP2,ACKR3,HMGB1,CCR3,ITGAV,CCR2 |
| 1.886e-02 | -3.97 | purine-containing compound catabolic process | biological process | GO:0072523 | 107 | 42 | 18204 | 5365 |
SAMHD1,NUDT3,IER3,ENPP4,NUDT19,PGM1,PDE2A,DNPH1,NUDT9,GAPDH,NUDT18,NUDT16,SUCLG2,PDE1A,SARM1,FITM2,NUDT4,UCP2,HINT1,NT5C2,FKRP,NUDT1,PFKFB2,BPGM,ACAT1,ENO2,PDE4B,NUDT7,URAD,PGK1,PDE7A,LIPA,OGDHL,ENTPD4,ENO1,PGAM1,HTR2A,PDE9A,PNP,PDE8A,LDHA,NUDT12 |
| 1.886e-02 | -3.97 | neuron apoptotic process | biological process | GO:0051402 | 107 | 42 | 18204 | 5365 |
GPX1,TUBA1A,RB1,ADNP,SLC1A1,BAX,STAMBP,SNCB,ROCK1,NPR2,NCSTN,GAPDH,PARP2,SIAH1,BOK,TP53,DLX1,ELK1,NR4A2,CLN8,KRAS,BCL2L1,POLB,DIO3,STXBP1,HRAS,PSEN1,VPS54,DNAJC5,FAS,AIFM1,ANGPT1,NAE1,CDK5,CNTFR,NDP,TMBIM6,HTRA2,NEFL,AKT2,FAM162A,NLRP1 |
| 1.893e-02 | -3.97 | Axon guidance | REACTOME pathways | R-HSA-422475 | 549 | 195 | 10285 | 3229 |
PSMA2,PSMB6,FGFR1,PSMB11,PSMA4,PAK6,PSMC4,VAV2,PSMB1,JAK2,CSNK2B,PPP2R1A,UBB,PTPN11,SIAH2,PSMD14,NCK1,ANGPT1,PSME1,SPTBN1,SHC3,CDK5R1,PSMD12,JAK1,CSF2,WASL,RGMB,ITGA2,CSNK2A1,MAP3K11,AGAP2,IL2RA,PSMB9,FGF3,APH1A,CNTN2,SPTAN1,ACTR2,PAQR3,SIAH1,MET,FGF1,GRB10,DUSP6,TRPC1,ACTB,L1CAM,SEMA7A,IL2RG,PIK3R2,HSP90AB1,PITPNA,RAF1,FGF22,KRAS,MAP2K1,ROCK1,MMP9,SDCBP,PSMD10,PEA15,HSP90AA1,PIK3CA,PSMD1,PSMB2,HRAS,PPP2CB,CUL3,PSMC1,CNTNAP1,RPS6KA4,LAMTOR3,ST8SIA4,PSMD4,SEMA5A,PHB1,ITGAV,IL3,ARPC2,PSMA1,ALCAM,RGMA,PAK2,EPHA2,RASGRP3,SHC1,BRAP,CSK,DLG4,CDK5,PSMB10,TYROBP,IL2,PSMC5,DNM2,PSMA3,PSMB5,EPHB6,PIK3R1,GPC1,PSMB7,PSMD3,CREB1,HSPA8,PRKACB,PRKCA,EPHA4,NCSTN,FGF17,EFNA3,PSMD7,SCN3B,SDC2,PSEN2,PPP5C,RAP1A,MSN,AP2M1,NTN4,LYPLA2,CACNB2,AP2S1,MYL6,FGF7,PIK3R3,NEFL,DUSP10,DLG1,SCN1B,RAC2,SPRED2,DLG3,HBEGF,CACNB4,PSMD6,PSME2,YES1,PSMB3,PEBP1,PPP2R5E,AP2A1,PSMA5,CAP2,FGF23,NEO1,CRMP1,PPP2R5A,RHOG,CDC42,YWHAB,WDR83,DOK4,UBA52,SCN2B,RAP1B,PRKCQ,EFNA5,FGF10,TIAM1,MYL12B,DUSP9,SRC,ROCK2,FRS3,PSMA6,NRP1,PRNP,IL5,GAB1,RHOB,LAMTOR2,KIT,PSENEN,PAK5,ARPC3,VWF,CAMK2G,SOS2,DOK5,IL2RB,CNTN1,CACNB3,FGF16,SPRED1,CFL1,RPS27A,EFNB1,MYL12A,PSMC3,VEGFA,DOK6,DUSP1,PLXNC1,SEM1,PSMB4 |
| 1.896e-02 | -3.97 | cell surface receptor protein serine/threonine kinase signaling pathway | biological process | GO:0007178 | 191 | 70 | 18204 | 5365 |
SMAD5,TGIF2,NOG,ITGB8,USP15,WIF1,SMAD4,CHRDL1,ID1,EXT1,COL3A1,ITGB5,JUN,ACVR1B,HFE,SRC,TGFB3,COL1A2,FERMT2,PDCD4,FLCN,SFRP1,MSX1,SOST,DDX5,NOTCH2,TWSG1,ACVR1C,TMEM100,SMAD3,TGFB2,FKBP8,TP53,DUSP22,BECN1,TGFBR2,FMOD,FUT8,MIR212,MSX2,PPARG,MIR21,CHST11,MIR30A,SMURF1,SMAD2,MIR183,ACVR1,NDP,BMPR2,ZYX,EID2,MAP1LC3A,RGMA,MSTN,LPXN,CITED1,SMAD1,SMAD9,BMPR1B,RGMB,FOS,SOSTDC1,TAB1,PML,EGR1,BMPR1A,CAV2,CFC1,FURIN |
| 1.896e-02 | -3.97 | COPI-mediated anterograde transport | REACTOME pathways | R-HSA-6807878 | 79 | 34 | 10285 | 3229 |
NAPA,DYNC1I1,KDELR2,FOLR1,DYNC1I2,ARF4,ARF1,RAB1B,RAB1A,TMEM115,ARFGAP1,SPTAN1,ARFGAP3,ARCN1,DCTN4,COPZ2,CD59,NAPG,DCTN3,TMED9,KDELR1,GOSR2,TMED3,SPTBN1,DCTN6,GOSR1,YKT6,BET1L,COPE,COG1,STX5,TMED7,DYNLL1,BET1 |
| 1.896e-02 | -3.97 | TACC3 (transforming acidic coiled-coil containing protein 3) | protein interactions | 10460 | 140 | 51 | 19454 | 5460 |
RAD23B,GNAQ,KLHL12,TUBB4B,TIMM8A,GTF2E2,MLLT6,SNX20,KBTBD4,SNAP29,CPLX1,AHCYL1,RNF20,KRAS,BAG2,ZYX,CLP1,PRPF19,KXD1,SLAIN2,CIB3,SVIP,FZR1,SEC23A,PLEKHO2,ZER1,UBE2M,METTL14,IPP,BORCS6,NUP62,OIP5,KDM1A,HSPA8,CORO6,MAPRE1,UBE2H,PDF,CCHCR1,BRCA1,BEX3,TUSC1,MAP3K21,CUL3,VIRMA,RORB,RAB14,PHF21A,TUBA1B,SRXN1,CCNF |
| 1.896e-02 | -3.97 | SERPINA1 (serpin family A member 1) | protein interactions | 5265 | 140 | 51 | 19454 | 5460 |
ERLEC1,TF,EGFL8,CHST10,CCR1,SELENOF,PDE6D,SERPINA1,SERPINA3,SOX2,CA8,LMAN1,KLK3,FUNDC2,OS9,DERL2,KRT8,RCHY1,AGPAT1,SMAD4,HP,SCGB1D1,PRKX,EDEM1,AZGP1,HSPA5,CLU,HSPA8,SYVN1,MIS12,RAP2A,SQSTM1,DERL1,LCN1,SDC2,SSR1,HBB,STX17,EDEM3,CFTR,CCNA2,SSBP2,TIMM10,ESR2,FBXO22,SRP54,HSP90AA1,KLK5,PRSS1,DCAF4,SAMHD1 |
| 1.896e-02 | -3.97 | WDR48 (WD repeat domain 48) | protein interactions | 57599 | 140 | 51 | 19454 | 5460 |
LDLR,USP46,H2AZ1,ZBTB2,DKC1,PRNP,POLR2I,DDRGK1,PPIB,CSNK2A1,MAP4,KPNA1,ID1,CRTAP,PCNA,CCT8,TCOF1,AHCYL1,CTNND1,TULP3,FBXL7,MGARP,TP53,TBK1,POLR2G,GPBP1L1,PNMA2,CSNK2B,TRMT11,ZBTB33,CCNF,RABIF,AR,CUL3,NOP16,AKT1,MYC,STK11,WDR20,BRCA1,DCAF4,CCT2,CIRBP,PSMA3,NMRAL1,DVL2,NHP2,STAU1,FAXC,ATG16L1,P3H1 |
| 1.897e-02 | -3.96 | AIP (aryl hydrocarbon receptor interacting protein) | protein interactions | 9049 | 162 | 58 | 19454 | 5460 |
TSSK1B,CCNF,SRC,BTG3,TAX1BP1,SNRNP40,YES1,SAMHD1,PDE7A,CIAO1,ILK,UBE2H,HSP90AA1,DCAF4,PSKH1,FAS,AKAP1,NMRAL1,RPA3,BAP1,BCL6,TOMM20,IRF7,DET1,AGO1,RLN2,PREP,PTPN1,HSP90AB1,EPHB6,CDK9,EGLN3,DYNC1I2,TTC9C,CSNK2A1,PRKX,FGR,DCAF11,BCL10,NTRK2,SLC39A7,FBXO11,POC1B,BCKDK,CLEC7A,DDR1,PTGES3,GCA,KHDC1,DYNC1I1,PPARA,APOBEC3D,RAF1,GNAQ,BIRC5,TNNI3K,GDI2,GLE1 |
| 1.904e-02 | -3.96 | human chr14q24.1 | chromosome location | human chr14q24.1 | 23 | 10 | 26134 | 5823 |
VTI1B,ERH,DCAF5,EXD2,TMEM229B,ARG2,SUSD6,RDH11,RDH12,SLC39A9 |
| 1.906e-02 | -3.96 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome_therapy_related | 21 | 11 | 16828 | 4835 |
SF3B1,RUNX1,KRAS,CBL,IDH1,SRSF2,TP53,KIT,IDH2,PTPN11,JAK2 |
| 1.906e-02 | -3.96 | myelodysplastic_syndrome_therapy_related | COSMIC cancer mutations | myelodysplastic_syndrome_therapy_related | 21 | 11 | 16828 | 4835 |
IDH2,JAK2,PTPN11,TP53,SRSF2,KIT,SF3B1,RUNX1,CBL,IDH1,KRAS |
| 1.907e-02 | -3.96 | EMG1 (EMG1 N1-specific pseudouridine methyltransferase) | protein interactions | 10436 | 109 | 41 | 19454 | 5460 |
POU5F1,RIT1,BRD3,ZCCHC9,CYP1A1,COPS5,RUNX1,MYC,IFI16,SMURF1,WIF1,RPL10,ESR2,FAM98A,TIMM21,SUMO2,EED,ZMAT5,MCPH1,PHB1,NUPR1,PSMB7,RPA2,EZH2,SOX2,CFTR,ATG16L1,TBK1,E2F4,RIGI,GOLGA7,AATF,H3C1,NOC4L,STAU1,EXOSC4,EMG1,EMC2,SNAPC1,RPA3,PSME1 |
| 1.907e-02 | -3.96 | SIPA1L3 (signal induced proliferation associated 1 like 3) | protein interactions | 23094 | 109 | 41 | 19454 | 5460 |
GSK3A,ANAPC2,KRT8,CCNF,ITGA6,CTNNA1,CDK9,EGLN3,VIRMA,ESR2,SRPK2,DYRK1A,HNRNPL,ACTB,RPGRIP1L,YWHAH,BTF3,YWHAG,CTNNB1,IFI16,DYRK1B,SFN,YWHAB,BICD2,RHOB,MYO6,YWHAZ,SQSTM1,ZYX,RNF41,TRIM37,PPP1CB,SOX2,SIPA1L1,RAF1,WDR83,TOP3B,ATG16L1,NUPR1,GRIK1,CAPZA2 |
| 1.908e-02 | -3.96 | SLC12A9 (solute carrier family 12 member 9) | protein interactions | 56996 | 52 | 22 | 19454 | 5460 |
TPRA1,CPSF4,OR4N2,GPR17,SLC41A3,P2RY1,LGALS8,ZNF526,UPK1A,CTXN1,ACACA,SEMA7A,LMBR1L,KCNA2,HSPA8,TMEM268,TMEM74,CX3CL1,POPDC2,MANSC1,LGALS3,CLRN2 |
| 1.908e-02 | -3.96 | H4C2 (H4 clustered histone 2) | protein interactions | 8366 | 52 | 22 | 19454 | 5460 |
ASF1A,RBBP4,RBBP7,CAND1,RAD21,SSRP1,VIRMA,TMPO,CBX5,MCM6,KMT5B,PARP2,H2AZ1,MACROH2A1,TRIM24,PPTC7,BRD3,CUL2,CUL3,MCM4,COPS5,H2AX |
| 1.908e-02 | -3.96 | Ruvbl2 (RuvB-like AAA ATPase 2) | protein interactions | 20174 | 52 | 22 | 19454 | 5460 |
PFDN6,PFDN2,INO80E,NOPCHAP1,NOP58,VPS72,WDCP,CCNF,PIH1D1,TTI2,DMAP1,CFTR,RPAP2,ZNHIT1,ACTL6A,PDRG1,DNAAF10,RUVBL1,CHMP1B,RPAP3,INO80C,TFPT |
| 1.908e-02 | -3.96 | SMIM3 (small integral membrane protein 3) | protein interactions | 85027 | 52 | 22 | 19454 | 5460 |
STX1A,SLC38A1,TMEM31,TMEM182,SMCO4,TM4SF18,SFTPC,SEC22A,LPAR6,CLDN11,PDCD1LG2,PMP22,CNIH1,FNDC9,BSCL2,EMP3,CLDN8,PLP1,PNMA1,TEX264,RPRM,CLEC7A |
| 1.908e-02 | -3.96 | SCRN1 (secernin 1) | protein interactions | 9805 | 52 | 22 | 19454 | 5460 |
TOLLIP,RBCK1,POPDC3,FBXO25,SPTBN1,SNRNP27,EZH2,RAB4A,TAB2,CDK5R1,HGS,STUB1,CTU1,SPPL3,TAB1,MBD5,GNAI2,ARL6IP6,FCGR2A,MCM3,COX10,DNAJB6 |
| 1.908e-02 | -3.96 | MCM9 (minichromosome maintenance 9 homologous recombination repair factor) | protein interactions | 254394 | 52 | 22 | 19454 | 5460 |
RFC2,MSH6,RFC3,RUVBL1,MCMBP,NFIL3,NF2,THBS3,NBN,RFC4,PNMA2,FAF2,DDX39A,NOP58,CAND1,SSR2,SF3B6,STK11,PSMD14,MCM8,API5,RFC5 |
| 1.909e-02 | -3.96 | TJP1 (tight junction protein 1) | protein interactions | 7082 | 297 | 100 | 19454 | 5460 |
USP15,H2AC4,HDAC6,ERCC3,CDK9,NUPR1,ANGPT1,RIGI,CRYBA4,TOLLIP,PSMA5,ERLEC1,CLDN6,ATP1A1,PEA15,STK24,BICD2,AR,CIAO1,SUGP1,CSK,ZNF507,VIRMA,RPGRIP1L,F11R,CSNK2B,CTTN,CTNNA1,UBN1,CCNF,PARD6A,TRIM68,RPA2,CFTR,CDC42,SIPA1L1,SUMO1,AATF,HMGB1,FBXW7,WDR3,CERS2,CLDN8,RTN4,SQSTM1,SIRT7,PML,RPA3,YWHAB,RASSF8,CTNNB1,YWHAG,XPO1,YWHAH,NDUFV2,WWP2,IFI16,SRSF10,SPTAN1,HNRNPL,KRT8,GJA1,FBXO32,CCR1,NDUFS6,ISG15,ACTN4,RAF1,RAB8B,FLOT1,TRIM37,KRAS,DHX16,FAM168A,ZYX,VMP1,CDKL2,HSP90AA1,YWHAZ,RHOB,DCAF4,BAG3,BTF3,SFN,MYC,ACTB,TUBB,CLDN3,DLST,VAPB,PPP1CB,NOTCH2,GJC1,CLDN4,STAU1,PSENEN,B9D2,STK26,CLDN1,HSPA8 |
| 1.910e-02 | -3.96 | bZIP_2 | pfam domains | PF07716 | 11 | 7 | 17795 | 5224 |
XBP1,CEBPE,TEF,HLF,NFIL3,CREBL2,CEBPG |
| 1.910e-02 | -3.96 | HlyIII | pfam domains | PF03006 | 11 | 7 | 17795 | 5224 |
PAQR9,PAQR8,MMD,PAQR3,ADIPOR1,ADIPOR2,PAQR4 |
| 1.910e-02 | -3.96 | Ribosomal_L7Ae | pfam domains | PF01248 | 11 | 7 | 17795 | 5224 |
RPL7A,SECISBP2L,GADD45B,GADD45A,GADD45G,RPS12,NHP2 |
| 1.910e-02 | -3.96 | Linker_histone | pfam domains | PF00538 | 11 | 7 | 17795 | 5224 |
H1-5,H1-6,SHPRH,H1-10,HP1BP3,H1-1,H1-3 |
| 1.913e-02 | -3.96 | regulation of endothelial cell differentiation | biological process | GO:0045601 | 47 | 21 | 18204 | 5365 |
BTG1,MIR21,MIR34A,MIR150,ROCK1,CTNNB1,MIR10A,ADD1,MIR1-1,VEGFA,IKBKB,ROCK2,IL1B,MIR200C,MIR495,PLCB1,PPP1R12A,MIR99B,TNF,F11R,TMEM100 |
| 1.913e-02 | -3.96 | regulation of telomerase activity | biological process | GO:0051972 | 47 | 21 | 18204 | 5365 |
WRAP53,PKIB,TNKS,SRC,MAPKAPK5,PRKCQ,PARM1,DKC1,CCT2,PTGES3,NEK2,GREM1,XRCC5,HNRNPA2B1,NEK7,HSP90AA1,HSP90AB1,HNRNPD,TCP1,KLF4,MYC |
| 1.915e-02 | -3.96 | dicarboxylic acid transport | biological process | GO:0006835 | 78 | 32 | 18204 | 5365 |
KCNJ10,FOLR1,CLN8,SLC13A5,ABCC5,UCP2,SLC7A11,SLC22A6,LRRC8D,SLC25A10,SLC1A1,SLC1A2,KCNJ8,SLC25A11,SLC25A32,SLC25A12,GJA1,ABCC2,SLC25A21,SLC19A2,ARL6IP5,PSEN1,SLC1A3,LRRC8A,GRM1,GRM2,SLC16A1,NTRK2,VPS54,LRRC8B,FOLR2,LRRC8C |
| 1.917e-02 | -3.95 | ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2) | protein interactions | 9181 | 197 | 69 | 19454 | 5460 |
PPP2CB,EEF1AKMT3,DNM2,FZR1,CDC5L,MAP1S,WWP2,PPP2R5A,UBXN6,MOV10,PRDX1,MAP3K14,DDRGK1,HDAC6,YWHAH,YWHAG,NCK1,SNRNP70,CAMSAP2,YWHAB,SKA1,IGF1R,RIGI,CAPZA1,UBE2A,RAF1,TOP3B,B3GNT2,TULP3,AURKAIP1,APOO,PPP2R1A,PNMA2,PLS3,TAF10,CCNF,LMBR1L,RRAS2,SRP54,RPP25L,RPL35,ESR2,VIRMA,SFN,CUL3,COPS7A,MYC,RHOB,FTSJ3,YWHAZ,UBE2H,MAPRE1,RPA3,AKAP1,HSPA8,FBXW7,UFL1,TRIM52,BET1,WDR83,ATG16L1,FGFR1,RPA2,PAK5,HECTD1,TRIM36,RPL26L1,KLC2,SCLT1 |
| 1.920e-02 | -3.95 | metencephalon development | biological process | GO:0022037 | 113 | 44 | 18204 | 5365 |
CNTN1,LDB1,OPHN1,HSPA5,TRNP1,PSEN1,CRKL,UQCRQ,SEMA4C,CBLN1,FZD4,ARCN1,KLHL1,MTPN,RPGRIP1L,MECP2,COQ8B,PAX6,ZNF365,EZH2,TUBA1A,NCSTN,MAP2K1,SLC25A46,HOXB1,HSPA8,CDK5,PDSS2,WNT7A,CLP1,COMT,CDK5R1,PROX1,CEND1,FCGR2B,NEUROD2,PTPN11,TP53,KCNC1,LPAR1,GNPAT,HNRNPD,RERE,IGF1R |
| 1.925e-02 | -3.95 | regulation of cytokine-mediated signaling pathway | biological process | GO:0001959 | 182 | 67 | 18204 | 5365 |
TBK1,RNF113A,MIR21,CCDC3,DICER1,MIR130A,MIRLET7C,PPARG,CPNE1,TICAM2,STAT2,EIF4E2,GFI1,MIR20A,IL1R2,OAS1,SAMHD1,IL7,SPATA2,NKIRAS2,YTHDF2,CASP4,CNOT7,TRIM44,MAVS,IKBKB,MIR125A,NR1H2,LSM14A,CAV1,IRF7,H2BC11,NLRP6,TANK,STAP1,PYCARD,PTPN11,MIR152,ISG15,CXCR4,IRF3,MIR98,MIR99A,ANGPT1,OTULIN,PELI3,PTPN1,NKIRAS1,PPP2CB,EXT1,SYK,PADI2,TRIM6,PYDC2,AGPAT1,GSTP1,TRAF2,IL6,TNFAIP3,TRIM32,MUL1,UBE2K,MIR101-1,MIR24-1,CCL5,ADIPOQ,PAFAH1B1 |
| 1.928e-02 | -3.95 | urinary_tract-carcinoma | COSMIC cancer mutations | urinary_tract-carcinoma | 16 | 9 | 16828 | 4835 |
STK11,PIK3CA,PTEN,KRAS,CTNNB1,HRAS,KIT,TP53,AKT1 |
| 1.928e-02 | -3.95 | serrated_adenoma | COSMIC cancer mutations | serrated_adenoma | 16 | 9 | 16828 | 4835 |
SMAD4,PTEN,PIK3CA,STK11,FBXW7,PIK3R1,TP53,KRAS,CTNNB1 |
| 1.928e-02 | -3.95 | large_intestine-colon-serrated_polyp-serrated_adenoma | COSMIC cancer mutations | large_intestine-colon-serrated_polyp-serrated_adenoma | 16 | 9 | 16828 | 4835 |
SMAD4,PTEN,PIK3CA,STK11,FBXW7,PIK3R1,TP53,CTNNB1,KRAS |
| 1.928e-02 | -3.95 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_II | 16 | 9 | 16828 | 4835 |
KRAS,GNA11,TP53,IDH1,FLRT2,IDH2,GNAQ,BAP1,PTEN |
| 1.928e-02 | -3.95 | skin-leg-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-leg-adnexal_tumour-malignant_adnexal_tumour | 16 | 9 | 16828 | 4835 |
KRAS,CTNNB1,KIT,TP53,IDH1,AKT1,JAK2,PIK3CA,PTEN |
| 1.928e-02 | -3.95 | renal_pelvis | COSMIC cancer mutations | renal_pelvis | 16 | 9 | 16828 | 4835 |
KRAS,CTNNB1,HRAS,TP53,ETV6,MSH6,PIK3CA,TERT,PTEN |
| 1.928e-02 | -3.95 | vagina | COSMIC cancer mutations | vagina | 16 | 9 | 16828 | 4835 |
PIK3CA,PTEN,KRAS,CTNNB1,HRAS,KIT,TP53,AKT1,JAK2 |
| 1.928e-02 | -3.95 | tubular | COSMIC cancer mutations | tubular | 16 | 9 | 16828 | 4835 |
PIK3CA,STK11,SMAD4,PTEN,TP53,CTNNB1,KRAS,FBXW7,PIK3R1 |
| 1.928e-02 | -3.95 | flank | COSMIC cancer mutations | flank | 16 | 9 | 16828 | 4835 |
AKT1,PTPN11,KRAS,GNA11,HRAS,PTEN,PIK3CA,GNAQ,BAP1 |
| 1.928e-02 | -3.95 | serrated_polyp | COSMIC cancer mutations | serrated_polyp | 16 | 9 | 16828 | 4835 |
FBXW7,PIK3R1,TP53,CTNNB1,KRAS,SMAD4,PTEN,PIK3CA,STK11 |
| 1.928e-02 | -3.95 | skin-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-adnexal_tumour-malignant_adnexal_tumour | 16 | 9 | 16828 | 4835 |
TP53,KIT,KRAS,CTNNB1,JAK2,AKT1,IDH1,PIK3CA,PTEN |
| 1.930e-02 | -3.95 | ATXN7 (ataxin 7) | protein interactions | 6314 | 106 | 40 | 19454 | 5460 |
SUPT7L,SPRY1,TAF10,ACTN4,SUPT3H,TRAF2,NUP62,SUMO1,VWF,PSMC1,PIAS1,LAMB2,SGF29,PICK1,EP300,DR1,PML,TAF9,TADA1,TRIM23,TADA3,PSMD7,CEP70,TAF5L,MYC,ENY2,RAB3D,ESR2,HNRNPL,TRIM54,SUMO3,SIAH1,SNX1,SUMO2,PSMC5,TRIM27,NELL2,THY1,UBE2I,PNMA1 |
| 1.930e-02 | -3.95 | PCF11 (PCF11 cleavage and polyadenylation factor subunit) | protein interactions | 51585 | 106 | 40 | 19454 | 5460 |
VRK1,HUWE1,DHX16,SSRP1,SNRPA,RPA3,EMC2,PLCB1,EWSR1,CDK8,RPA2,POLR2C,SUPT5H,RAF1,CFTR,MRPL50,TOP1,ARF6,TNPO3,NUP35,SRPK2,ESR2,EGLN3,EIF4A3,ALYREF,SSU72,CPSF1,PHAX,RBM27,ANKRD50,CLP1,CDKN2AIP,PDCD4,PEA15,ERCC3,MOV10,AR,CPSF2,HNRNPA1,ANAPC15 |
| 1.930e-02 | -3.95 | HSP90AB2P (heat shock protein 90 alpha family class B member 2, pseudogene) | protein interactions | 391634 | 106 | 40 | 19454 | 5460 |
KRAS,FKBP8,PTGES3,METTL22,MEPCE,RPA3,TESK2,RUVBL2,CLK1,ACTR2,RPA2,LMNA,TP53,RAF1,CDK7,SOX2,PRKCE,CAND1,SRPK2,HSP90AB1,EGLN3,PHB1,EEF1AKMT3,CCNF,HRAS,BRCA1,SLC2A1,DNAJB6,FGR,HSP90AA1,AHSA1,COP1,DNAJC7,CUL3,CUL2,MYC,CSK,MAP3K14,CSNK2A1,COPS5 |
| 1.930e-02 | -3.95 | NSD1 (nuclear receptor binding SET domain protein 1) | protein interactions | 64324 | 106 | 40 | 19454 | 5460 |
SPPL3,RORB,APEX1,ESR2,VIRMA,H2AZ1,ZNF330,NR2E1,MECP2,AGR2,NTRK3,BRD3,HMGA1,MDFI,H2BC9,NR2F6,AR,ZNF692,H3C1,ASF1A,RPL4,COIL,RIGI,MDC1,RPA3,RPL31,SIRT7,PABPC1,RPL23A,NUP50,CBX3,LMNA,RPA2,PPARG,TOP3B,H1-5,VDR,JUN,H1-3,SOX2 |
| 1.930e-02 | -3.95 | TASOR (transcription activation suppressor) | protein interactions | 23272 | 106 | 40 | 19454 | 5460 |
SUPT5H,POLR2C,CAPN2,TBC1D4,RPA2,EZH2,SKA3,EMG1,RPA3,PRIM2,SNRPA,DDX46,RPS28,PSME1,TCOF1,PSMD12,TRIM52,SSRP1,PTGES3,FTL,B9D2,SLC31A1,KDM1A,HNRNPA1,SNRPB,IFI16,CDC16,MYC,AP2M1,RB1,CCNF,CIB2,LURAP1,TOM1L1,ESR2,NOP58,MATR3,TOP1,SNRNP40,ZCCHC7 |
| 1.930e-02 | -3.95 | THRA (thyroid hormone receptor alpha) | protein interactions | 7067 | 106 | 40 | 19454 | 5460 |
MED21,KPNA1,MOV10,CREBBP,TAF7,HR,YWHAH,BTF3,RGN,SUV39H1,BUB3,HNRNPL,MED17,TAF11,SRC,GTF2B,RXRG,CREB1,ENO1,LIG3,TRIM24,UBE2I,COPS2,LDLR,CDK8,BTG1,PCSK2,CCND1,TXNRD1,CDK7,HDAC3,TRIM63,THRAP3,MEF2A,PTGES3,PML,XRCC5,EP300,SELENOP,C1D |
| 1.930e-02 | -3.95 | CLUH (clustered mitochondria homolog) | protein interactions | 23277 | 137 | 50 | 19454 | 5460 |
KIF2A,WDR37,MAP1LC3B,TP53,MOB3C,HDAC11,DNAJC2,ARPC3,COX8A,CLPB,IMMP2L,PSMA1,DCAF4L2,PPP3CA,DNAJC7,TRAPPC2L,KRT8,FAHD1,PSMB5,RPL9,EGLN3,PRNP,PHYH,NOP58,GKAP1,PIH1D1,PRKCA,WWP1,HSP90B1,RPA2,SIRT7,PRPF4,RPA3,FOXD3,THOC3,RPL27,STAU1,HMGB1,MRPL40,HSCB,MCM4,PMPCA,UBE2H,DCAF4,DLST,CCNF,NCKAP1,PSMB6,RPP25L,RPGRIP1L |
| 1.934e-02 | -3.95 | Estrogen signaling pathway | KEGG pathways | hsa04915 | 98 | 44 | 7161 | 2463 |
SHC1,PLCB1,FKBP4,SP1,HRAS,SRC,ATF4,CREB3L4,GRM1,GABBR1,MMP9,RAF1,PRKACB,HSP90AB1,FOS,GNAO1,GNAI3,PIK3R1,CREB1,SHC3,KRAS,HBEGF,GNAQ,ESR2,PIK3R2,CALML5,ADCY3,PLCB2,AKT1,HSP90AA1,PIK3R3,KCNJ3,PIK3CA,HSPA8,SOS2,OPRM1,GNAI2,AKT2,ADCY2,JUN,MAP2K1,AKT3,CREB3,HSP90B1 |
| 1.934e-02 | -3.95 | Estrogen signaling pathway | KEGG pathways | ko04915 | 98 | 44 | 7161 | 2463 |
RAF1,PRKACB,MMP9,GABBR1,ATF4,GRM1,CREB3L4,HRAS,SRC,FKBP4,SP1,SHC1,PLCB1,AKT1,ADCY3,PLCB2,PIK3R2,CALML5,GNAQ,HBEGF,ESR2,SHC3,CREB1,KRAS,GNAI3,PIK3R1,HSP90AB1,FOS,GNAO1,SOS2,PIK3CA,HSPA8,KCNJ3,PIK3R3,HSP90AA1,HSP90B1,AKT3,CREB3,MAP2K1,AKT2,ADCY2,JUN,GNAI2,OPRM1 |
| 1.934e-02 | -3.95 | regulation of cation channel activity | biological process | GO:2001257 | 116 | 45 | 18204 | 5365 |
EDNRA,SLMAP,TMSB4X,JPH4,KCNS1,CAV1,EPO,FKBP1A,KCNAB1,CLIC2,VAMP2,MIR200C,CRHR1,SRI,FGF13,SUMO1,MIR448,GPR35,KCNIP2,CACNB4,FKBP1B,GSTO1,NOS1AP,MIR208A,DLG1,MIR153-1,MIR212,STIM1,SELENON,MIR192,CACNB3,MIR24-1,CACNB2,MMP9,MIR1-1,SCN1B,HPCA,STAC3,GSTM2,MIR30D,DRD3,FGF12,MIR208B,HOMER1,NETO1 |
| 1.938e-02 | -3.94 | TPRA1 (transmembrane protein adipocyte associated 1) | protein interactions | 131601 | 35 | 16 | 19454 | 5460 |
OSBPL8,DOLK,FAM241B,GHITM,RAB4A,SLC30A5,ATG9A,TOP3B,RETSAT,BMPR1B,RAB11A,SLC6A8,SPPL3,HNRNPL,SC5D,EFNA3 |
| 1.938e-02 | -3.94 | RMI1 (RecQ mediated genome instability 1) | protein interactions | 80010 | 35 | 16 | 19454 | 5460 |
PML,RPA3,UBE3A,FAAP100,NR1H2,PFDN1,EGLN3,CUL3,TOP3B,MARCKSL1,RMI2,BRCA1,HSPA13,RPA2,TOPBP1,CCDC69 |
| 1.938e-02 | -3.94 | EIF4EBP2 (eukaryotic translation initiation factor 4E binding protein 2) | protein interactions | 1979 | 35 | 16 | 19454 | 5460 |
RDH12,LSM3,EIF3G,BAG3,EIF3D,CDK4,NFYA,EIF3E,EIF4E,RPS27L,EIF4A2,TXN,FHL3,EIF3K,HNRNPA2B1,EIF4E2 |
| 1.938e-02 | -3.94 | MPLKIP (M-phase specific PLK1 interacting protein) | protein interactions | 136647 | 35 | 16 | 19454 | 5460 |
SERPINH1,RBM27,PPIF,NTAQ1,XPO1,CDK7,GORASP2,RAF1,SUGP1,EGLN3,DBR1,KCTD17,SF3B4,POLR2F,THY1,MRPL53 |
| 1.938e-02 | -3.94 | ZNF724 (zinc finger protein 724) | protein interactions | 440519 | 35 | 16 | 19454 | 5460 |
VIRMA,RPL28,PRNP,RPL7L1,RPS16,H1-6,FGFBP1,FBLN5,LTBR,LHX2,RPL26L1,TEX19,LMNA,FAXC,NOTCH2,RPL27A |
| 1.938e-02 | -3.94 | JAG1 (jagged canonical Notch ligand 1) | protein interactions | 182 | 35 | 16 | 19454 | 5460 |
CUL3,NOTCH2,JUN,SEC62,RHOG,RHOB,HGS,HRAS,FOS,MTDH,RAC2,KRAS,FBXW7,RHOJ,VIRMA,CAV1 |
| 1.938e-02 | -3.94 | UBAP1 (ubiquitin associated protein 1) | protein interactions | 51271 | 35 | 16 | 19454 | 5460 |
VPS28,TSG101,MYD88,ZYX,ACTA2,ENO1,UBAP1,RIT1,PPIC,RPA2,BICD2,XPO1,ATG16L1,MOV10,CDC37L1,WWP2 |
| 1.938e-02 | -3.94 | SDE2 (SDE2 telomere maintenance homolog) | protein interactions | 163859 | 35 | 16 | 19454 | 5460 |
RPS29,CUL3,MYC,RIT1,HAUS2,UBE2H,MED4,DTL,RPA2,PCNA,PML,RPA3,LMBR1L,MEPCE,EGLN3,KRAS |
| 1.938e-02 | -3.94 | P4HTM (prolyl 4-hydroxylase, transmembrane) | protein interactions | 54681 | 35 | 16 | 19454 | 5460 |
PDIA2,NCR3,SDF2L1,SFTPC,TMEM106A,GGH,CBLN4,CFC1,GPR37,DNAJB9,LPAR1,CD1D,RHOU,AIFM1,GXYLT1,TMEM106B |
| 1.938e-02 | -3.94 | ABRAXAS1 (abraxas 1, BRCA1 A complex subunit) | protein interactions | 84142 | 35 | 16 | 19454 | 5460 |
PSMC5,RABGGTB,SUMO2,DYRK1A,FANCG,MDC1,ESR2,AKT1,BABAM1,CUL3,BORCS6,PPP1CC,CFTR,ZMYM3,BRCA1,WTAP |
| 1.940e-02 | -3.94 | Iso_dh | smart domains | SM01329 | 5 | 4 | 9717 | 2575 |
IDH3B,IDH2,IDH3A,IDH1 |
| 1.952e-02 | -3.94 | MRPL34 (mitochondrial ribosomal protein L34) | protein interactions | 64981 | 55 | 23 | 19454 | 5460 |
RHOG,MRPL18,UBE2H,USP15,MYC,RPL6,MRPL9,TRA2A,RBIS,RANBP6,MRPL50,RPL19,MRPL53,MRPL13,CSNK1G3,MTRES1,MACROH2A2,RAP1A,MRPL47,MRPL10,MRPL12,MRPL41,MRPL52 |
| 1.952e-02 | -3.94 | PLEKHH3 (pleckstrin homology, MyTH4 and FERM domain containing H3) | protein interactions | 79990 | 55 | 23 | 19454 | 5460 |
EFNB1,CXCR4,TMED7,TACR3,RIGI,PTGES3,SLC31A1,TGFBR2,SOX2,PRMT2,CTDSP2,RFXANK,TOP3B,AVPR1B,CTXN1,GNAI3,CCNF,ABHD17A,CX3CL1,PRNP,MANSC1,UBXN6,MAPK4 |
| 1.952e-02 | -3.94 | DOCK1 (dedicator of cytokinesis 1) | protein interactions | 1793 | 55 | 23 | 19454 | 5460 |
STK16,CRKL,SURF4,SDC2,IPCEF1,MAP1LC3B,ARL4A,MEPCE,CYTH2,KRAS,RHOG,ELMO2,SMAD4,FBXW11,RHOB,ATG9A,SRC,VIRMA,ESR2,HNRNPL,ELMO1,RAC2,INPP5K |
| 1.952e-02 | -3.94 | COMMD5 (COMM domain containing 5) | protein interactions | 28991 | 55 | 23 | 19454 | 5460 |
SMG8,COMMD9,CCDC22,INSYN1,PCCB,NFKB1,SRPK2,VPS26C,COMMD6,GGT7,RB1,E2F6,STMN2,NCSTN,TUBA1A,COMMD3,DDX39A,COMMD8,NEU1,RAD21,RLIM,COMMD2,CNKSR3 |
| 1.952e-02 | -3.94 | TENM3 (teneurin transmembrane protein 3) | protein interactions | 55714 | 55 | 23 | 19454 | 5460 |
CDC42,LCN6,TRAF2,CUL3,EDDM3B,TANK,RLN2,ARL15,RHOB,SMAD4,RAC2,SEC61B,PLAC9,DNAJC3,MME,OS9,CLU,RIGI,VIRMA,SIAE,RBCK1,CX3CL1,KRAS |
| 1.952e-02 | -3.94 | BACH1 (BTB domain and CNC homolog 1) | protein interactions | 571 | 103 | 39 | 19454 | 5460 |
POU5F1,SLX1A,DCAF4,XPO1,OST4,MOV10,TMEM208,SFN,CUL3,EGLN3,JAK2,VIRMA,DYNLL1,FBXO22,EED,CYTH1,SMAD3,CSNK1A1,CSNK1A1L,EZH2,SCHIP1,NFE2L2,SOX2,MAFG,CREBZF,CFTR,HOXB8,ATG16L1,TP53,SOCS2,RPS27A,SLC18B1,SKP1,BACH1,RBCK1,SLC39A7,DDIT3,FBXO3,DDX39B |
| 1.952e-02 | -3.94 | LSM14B (LSM family member 14B) | protein interactions | 149986 | 103 | 39 | 19454 | 5460 |
FZR1,ESR2,HOMER3,CTNNA1,FUBP3,RPS20,SNRNP70,POU5F1,IGF2BP1,WWP2,MOV10,CLPX,MYC,ZMYND11,NTAQ1,CPEB1,XPO1,STAU1,FBXW7,CHCHD2,G3BP1,PDHB,FXR2,HUWE1,POLDIP2,MEPCE,PML,LSM14A,BAP1,SEMG2,EZH2,HEXIM1,YTHDF2,TOP3B,RAF1,LGR4,SOX2,LBR,PPP2R1A |
| 1.952e-02 | -3.94 | TAF10 (TATA-box binding protein associated factor 10) | protein interactions | 6881 | 103 | 39 | 19454 | 5460 |
TADA1,BRD3,SETD7,RIT1,TAF9,TADA3,PRPF31,RIOK2,ZCCHC10,MYC,TAF5L,TAF7,ENY2,HSP90AB1,TAF11,DHX15,PRNP,SPTAN1,PHF21A,GTF2F2,UBE2I,PSMC5,TAF10,TAF2,SUPT7L,CFTR,SUPT3H,TP53,ATG16L1,RAF1,RIGI,FTL,RPS27A,MCM6,KPNA2,KRAS,SGF29,DR1,SPATA25 |
| 1.952e-02 | -3.94 | CD63 (CD63 molecule) | protein interactions | 967 | 103 | 39 | 19454 | 5460 |
CD81,TIMP1,MBLAC2,TMEM208,KDSR,REEP6,FITM2,CD9,TM4SF18,LGALS8,DOLK,POR,FAM241B,STARD3NL,TSG101,RETREG3,FAM210A,RAB35,ITGA6,LGALS3,REEP4,YIPF3,ALG11,YIPF5,MAP1LC3B,TSPAN3,SIGMAR1,GPD2,SDCBP,HSPA8,TSPAN15,TMT1A,HSDL1,PLSCR1,LPCAT3,GABARAP,TMEM47,KIT,CERS2 |
| 1.953e-02 | -3.94 | germ plasm | cellular component | GO:0060293 | 26 | 13 | 19108 | 5553 |
ASZ1,ANKRD34B,HENMT1,MOV10,MAEL,SNRPG,TDRD7,PIWIL3,PIWIL2,DDX4,PIWIL1,CARHSP1,PIWIL4 |
| 1.953e-02 | -3.94 | P granule | cellular component | GO:0043186 | 26 | 13 | 19108 | 5553 |
ASZ1,ANKRD34B,MOV10,HENMT1,PIWIL3,TDRD7,PIWIL2,MAEL,SNRPG,DDX4,PIWIL1,CARHSP1,PIWIL4 |
| 1.953e-02 | -3.94 | pole plasm | cellular component | GO:0045495 | 26 | 13 | 19108 | 5553 |
MOV10,HENMT1,ANKRD34B,ASZ1,PIWIL3,TDRD7,PIWIL2,MAEL,SNRPG,PIWIL1,DDX4,PIWIL4,CARHSP1 |
| 1.953e-02 | -3.94 | ANAPC2 (anaphase promoting complex subunit 2) | protein interactions | 29882 | 226 | 78 | 19454 | 5460 |
TTC1,EP300,ANAPC16,RNF34,SKP1,SRI,NPTN,NEK2,PSMC4,TOMM22,CNDP2,KLC2,CTBP1,UBE2S,LMBR1L,STUB1,GRIA1,CEP97,DYRK1A,ESR2,CDC20,MAD2L1,POLR2B,ATP5F1B,LDHA,UFD1,ANAPC15,LDHB,CEP85,PYCR2,CUL3,DHPS,PYCR1,CREBBP,CDC16,RIT1,ANAPC4,PTTG1,SMAD2,HSP90AA1,CCT2,CKB,ABCE1,RPAP3,MDC1,FKBP8,ETFA,KRAS,EPHA4,NUP107,ANAPC11,CSTF2T,SOX2,NUDCD3,ANAPC13,TP53,MACO1,PSMC3,GRAP2,NUDT19,RB1,SRP14,DNM2,CCT7,CDC5L,CACYBP,CNTROB,MDM2,SUMO2,FZR1,EIF2S1,COPS5,NDC80,CDC26,DRG1,CDC23,DNAJC7,FKBP4 |
| 1.953e-02 | -3.94 | positive regulation of podosome assembly | biological process | GO:0071803 | 11 | 7 | 18204 | 5365 |
SRC,LCP1,MSN,CSF2,IL5,CAPG,TNF |
| 1.953e-02 | -3.94 | regulation of protein localization to Cajal body | biological process | GO:1904869 | 11 | 7 | 18204 | 5365 |
CCT7,CCT8,MEPCE,DKC1,TCP1,CCT2,CCT5 |
| 1.953e-02 | -3.94 | regulation of peptidyl-cysteine S-nitrosylation | biological process | GO:2000169 | 11 | 7 | 18204 | 5365 |
TXN,MIR212,ATP2B4,SNTA1,TBC1D24,NOS1AP,MIR132 |
| 1.953e-02 | -3.94 | prenylation | biological process | GO:0097354 | 11 | 7 | 18204 | 5365 |
PGGT1B,AIPL1,PLPP6,PTAR1,RABGGTB,RCE1,FNTB |
| 1.953e-02 | -3.94 | response to glycoprotein | biological process | GO:1904587 | 11 | 7 | 18204 | 5365 |
MAN1A2,EDEM1,EDEM2,F7,EDEM3,NPPC,TSHR |
| 1.953e-02 | -3.94 | dendrite arborization | biological process | GO:0140059 | 11 | 7 | 18204 | 5365 |
PHACTR1,NRP1,CHRNA7,TPBG,IGF2BP1,PTN,ZNF365 |
| 1.953e-02 | -3.94 | protein insertion into ER membrane by stop-transfer membrane-anchor sequence | biological process | GO:0045050 | 11 | 7 | 18204 | 5365 |
EMC2,EMC9,EMC4,EMC8,EMC10,EMC1,EMC6 |
| 1.953e-02 | -3.94 | negative regulation of cholesterol metabolic process | biological process | GO:0090206 | 11 | 7 | 18204 | 5365 |
SOD1,MIR185,MIR342,ERLIN2,CH25H,MIR98,ERLIN1 |
| 1.953e-02 | -3.94 | protein prenylation | biological process | GO:0018342 | 11 | 7 | 18204 | 5365 |
PGGT1B,RABGGTB,FNTB,RCE1,PTAR1,AIPL1,PLPP6 |
| 1.953e-02 | -3.94 | blood vessel endothelial cell differentiation | biological process | GO:0060837 | 11 | 7 | 18204 | 5365 |
HEY2,CCM2,TMEM100,LIPA,NRP1,RBPJ,PROX1 |
| 1.953e-02 | -3.94 | negative regulation of collagen biosynthetic process | biological process | GO:0032966 | 11 | 7 | 18204 | 5365 |
EMILIN1,CYP7A1,NPPC,MIR218-1,CYGB,IL6,MIR29A |
| 1.953e-02 | -3.94 | positive regulation of protein localization to Cajal body | biological process | GO:1904871 | 11 | 7 | 18204 | 5365 |
CCT7,CCT8,CCT5,MEPCE,DKC1,CCT2,TCP1 |
| 1.953e-02 | -3.94 | regulation of macrophage apoptotic process | biological process | GO:2000109 | 11 | 7 | 18204 | 5365 |
IRF7,CCL5,MIRLET7B,MEF2C,CCR5,ST6GAL1,SELENOS |
| 1.953e-02 | -3.94 | negative regulation of transcription by RNA polymerase I | biological process | GO:0016479 | 11 | 7 | 18204 | 5365 |
CREBBP,NOP53,MACROH2A2,MAF1,MACROH2A1,SMARCA5,DEDD |
| 1.953e-02 | -3.94 | tripeptide transport | biological process | GO:0042939 | 11 | 7 | 18204 | 5365 |
SLC25A39,SLC15A1,NHERF1,GJA1,SLC15A2,ABCC5,SLC7A11 |
| 1.953e-02 | -3.94 | regulation of establishment of protein localization to telomere | biological process | GO:0070203 | 11 | 7 | 18204 | 5365 |
CCT5,DKC1,CCT2,TCP1,WRAP53,CCT7,CCT8 |
| 1.958e-02 | -3.93 | regulation of calcium ion transmembrane transport | biological process | GO:1903169 | 170 | 63 | 18204 | 5365 |
GSTO1,G6PD,PLN,MIR208A,NOS1AP,TLR9,SLC8A1,ATP1A2,MIR21,F2,ATP1B1,SELENON,STIM1,PML,JPH4,CAV1,CLIC2,EPO,FKBP1A,NPSR1,CXCL10,PPP3R2,MIR200C,CAV3,CRHR1,SRI,UBASH3B,SUMO1,GPR35,PLP1,DRD1,PRKCE,CACNB4,FKBP1B,TMBIM6,TRPC1,VDAC1,GSTM2,STAC3,PPP3CA,TMEM38B,APLNR,DRD3,THY1,PIK3CG,PDE4B,MIR208B,PRNP,PSEN2,XCL1,CACNB3,CX3CL1,CXCL9,CACNB2,LACRT,IL13,CXCL11,MIR1-1,SESTD1,VMP1,BAK1,HPCA,BAX |
| 1.959e-02 | -3.93 | SKP2 (S-phase kinase associated protein 2) | protein interactions | 6502 | 281 | 95 | 19454 | 5460 |
KPNA1,CDK12,SPP1,SMAD4,TIAM1,COPS5,ELOC,LRRC40,USP2,CDK9,PTP4A3,FZR1,SCG2,MYBL2,RB1,DISC1,NHERF1,DUSP1,YTHDF2,CDK4,CAMK2G,TOLLIP,PDCD4,BRAP,AR,NONO,KPNA6,USP14,DNAJC5,GMNN,AKT1,CCNB1,CDC20,UBE2L3,UBB,ZNF507,STUB1,GSTP1,UBE2M,UBAP1,CDK1,RPA2,BTG2,CCNA2,CCND1,SQSTM1,RPA3,NBN,LGI1,CDKN1B,YWHAB,IKBKB,IQSEC1,CENPW,PFDN5,LRWD1,STK3,TTC9C,IFI27,COPS2,SDHAF2,PHB1,BTG1,RND3,RNF126,DCUN1D3,CKS1B,PFDN1,RFC2,RUVBL1,TRIM21,CDK5,MMP9,MEF2C,SP1,HSP90AA1,MCM8,BRCA1,SAMHD1,BRMS1,UFD1,BAG3,USP13,MYC,COPS7A,CUL2,PAQR4,MAD2L1,SNRPB2,JAK2,RNF7,CDKN1A,SKP1,CRY1,EP300 |
| 1.960e-02 | -3.93 | Thyroid hormone signaling pathway | KEGG pathways | hsa04919 | 116 | 51 | 7161 | 2463 |
STAT1,AKT2,PLN,PRKCB,PIK3R3,SLC16A10,BAD,PIK3CA,HDAC3,ATP1B1,ATP1B3,MED13L,KRAS,PIK3R1,DIO3,AKT1,PLCB2,PIK3R2,MED30,PLCB1,MED4,ATP1A1,CCND1,TBC1D4,CREBBP,MDM2,MAP2K1,CTNNB1,SLC2A1,MYC,SIN3A,ATP1A3,AKT3,RXRG,RHEB,PRKCA,ACTB,DIO2,MED27,ATP1A2,MED17,ITGAV,DIO1,NOTCH2,TP53,SRC,HRAS,EP300,PFKFB2,PRKACB,RAF1 |
| 1.960e-02 | -3.93 | TUBB2B (tubulin beta 2B class IIb) | protein interactions | 347733 | 194 | 68 | 19454 | 5460 |
GABRA1,CDKN1A,HEXIM1,ANXA7,TCP11L1,HSPA8,RPA3,INPPL1,BAP1,METTL22,RGS2,HSPA5,UFL1,BTF3,USP14,RSPH1,CABCOCO1,MYC,CUL3,RAB11A,HSP90AA1,ANAPC4,COP1,UBE2H,CCT2,FAS,PSMD14,CSNK2B,SMU1,CCNF,FAM177A1,DLG4,TUBA1B,KCTD9,RPL35,TUBA1A,ZMYM4,NEU1,PLD3,TUBB4B,PDHA1,UBE3A,EMC2,FAF1,OSTM1,MEPCE,RPS4X,PRPS1,EPHA4,HDAC6,LAMP3,CD81,CDC42SE2,DPP4,MICB,GMPPB,POU5F1,CBL,CLP1,SNRNP70,SHC1,NDST3,AIFM1,EFNA3,RCHY1,DIRAS3,CD1A,CCT7 |
| 1.960e-02 | -3.93 | NCAPG (non-SMC condensin I complex subunit G) | protein interactions | 64151 | 194 | 68 | 19454 | 5460 |
B3GNT2,FEN1,PPP2R1A,ACTR1A,TNPO2,TUBB4B,MTA2,CYB5B,EFNB1,RUVBL2,KRAS,RBBP7,DNAJC30,KPNA2,RUVBL1,MCM6,VTA1,AHCYL1,RAD21,UBXN6,POLB,H2AC4,MED4,PPP3CA,USP15,FBXO32,EEF1AKMT3,SUMO2,DERL2,CCAR2,EGLN3,PTP4A3,CFTR,MED23,RPA2,CDK1,ARCN1,HECTD1,ACACA,RPA3,PML,HSPA8,KDM1A,SMC4,FBXW7,SMARCA5,MYC,FOXA3,GPR17,CUL3,PSMD1,GGH,PRSS1,UBE2H,LMBR1L,LIG3,TUBA1B,CHRM4,DPEP1,CYB5R3,PSMC5,PRMT5,MATR3,RBBP4,ADRM1,BMP1,ESR2,VIRMA |
| 1.962e-02 | -3.93 | adult locomotory behavior | biological process | GO:0008344 | 81 | 33 | 18204 | 5365 |
CSTB,ARCN1,FXN,FGF12,FKRP,CEND1,EPS8,ATP1A2,TBCE,ZMPSTE24,SNCG,TMOD1,HTRA2,GLRB,ABHD12,CXCL12,NLGN2,CACNB4,DRD1,HOXB8,HEXA,TUBA1A,CNP,NR4A2,CLN8,PAFAH1B1,PPT1,MECP2,NTF4,GLRA1,KLHL1,EPHA4,KCNJ10 |
| 1.963e-02 | -3.93 | ATR (ATR serine/threonine kinase) | protein interactions | 545 | 210 | 73 | 19454 | 5460 |
OPRM1,GPR17,SCN3B,CUL3,RHEB,CD226,BRCA1,RIT1,DTL,CDC73,HSP90AA1,CREB1,SCN2B,DCLRE1C,CINP,MCPH1,EFNA5,VIRMA,PPP5C,TPT1,PGRMC1,EEF1E1,FAM234A,KLRD1,CDC42,HCST,RPA2,XRCC5,SIRT7,NBN,PML,RPA3,CD40,TERT,EP300,NPTN,PPP2R3A,AATF,FAM174A,FAM133B,DDRGK1,E4F1,FXYD6,TUBG1,NCR3LG1,TOPBP1,POU5F1,FBXO32,CD274,CDC5L,CDK9,TP53,MGARP,H2AX,PIK3CA,CA14,RNF126,CYB5B,RAD1,MTA2,GEMIN7,CDKN2C,OSTM1,ALKBH4,SPSB1,SNIP1,NOSIP,SEMA4C,KRAS,TNFSF8,CD80,MSH6,RIGI |
| 1.965e-02 | -3.93 | NUP54 (nucleoporin 54) | protein interactions | 53371 | 134 | 49 | 19454 | 5460 |
TPM3,EXOC1,XPO1,IFI16,TEX12,KPNA1,CDC23,AGR2,SKIC8,ADD1,HOMER3,ETV6,NUP35,SPG21,ANAPC13,STPG4,NUP153,RANBP1,CENPM,NUPR1,HGS,GINS4,GLE1,CPNE2,EFHC1,HAPSTR1,GARRE1,KRAS,G3BP1,NUP107,CCDC85B,MYC,MAPRE1,CCHCR1,EXOC8,PELO,RAN,HOMER1,TRIM54,SMYD3,LPXN,NDE1,ATG16L1,NUP62,SCLT1,SSR1,DCTN3,SNAPC1,OIP5 |
| 1.965e-02 | -3.93 | NCAM signaling for neurite out-growth | REACTOME pathways | R-HSA-375165 | 276 | 103 | 10285 | 3229 |
PSMA1,PSMC3,SPRED1,PSMD4,PHB1,IL3,RPS27A,PSMB4,RASGRP3,SHC1,DUSP1,SEM1,IL5,HRAS,KIT,LAMTOR2,PPP2CB,PSMA6,PEA15,PRNP,PSMB2,PSMD1,LAMTOR3,CAMK2G,IL2RB,ST8SIA4,CACNB3,FGF16,PSMC1,CUL3,VWF,KRAS,MAP2K1,RAP1B,RAF1,WDR83,UBA52,FGF22,DUSP9,SRC,PSMD10,FRS3,FGF10,PSMA5,FGF23,PAQR3,MET,PSMB3,PEBP1,CNTN2,PPP2R5E,SPTAN1,IL2RG,PPP2R5A,FGF1,DUSP6,YWHAB,MAP3K11,NEFL,DUSP10,HBEGF,PSMD6,CACNB4,PSME2,FGF3,IL2RA,SPRED2,PSMB9,CACNB2,RAP1A,SHC3,CSF2,PSMD12,FGF7,JAK1,PSMD14,PPP2R1A,UBB,ANGPT1,PSME1,PPP5C,SPTBN1,FGF17,PSMD7,PSMB10,FGFR1,PSMC5,IL2,PSMB11,PSMA4,BRAP,CSK,DLG4,PSMA2,PSMB6,PSMB1,PSMB7,JAK2,PSMD3,CREB1,PSMC4,PSMA3,PSMB5 |
| 1.970e-02 | -3.93 | - | gene3d domains | 1.20.140.150 | 57 | 24 | 14470 | 4137 |
MOSMO,TMEM204,EMP2,CLDN24,EMP3,PMP22,TMEM182,CLDN11,LHFPL2,TMEM114,CACNG3,CLDN1,CLDN8,CLDN3,TMEM47,CLDN4,CLDN6,CLDN12,CLDND1,CLDN14,CLDN9,CLRN2,LHFPL6,CLDN22 |
| 1.973e-02 | -3.93 | MCPH1 (microcephalin 1) | protein interactions | 79648 | 100 | 38 | 19454 | 5460 |
RSL24D1,VIRMA,NMI,FZR1,HNRNPL,EIF4A2,LGALS3,WNT10B,ENO1,TOPBP1,DNAJC19,TSEN54,SKIC8,FBXW11,BRCA1,MT2A,HSPA5,MDC1,ABCC2,KDM1A,KRAS,USP8,RUVBL2,EMG1,HSPD1,NBN,HNRNPA2B1,SMARCB1,POLR2G,TAF1D,AKIP1,H2AX,CDK7,GABARAPL2,CFTR,AKR7A2,CCT5,TPT1 |
| 1.973e-02 | -3.93 | PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3) | protein interactions | 5289 | 100 | 38 | 19454 | 5460 |
HSPA5,NRBF2,RAB5A,RAB9A,PGK1,RPA3,PITPNA,RAB4A,KRIT1,VPS33A,RPA2,JOSD1,MYH1,TP53,PGRMC1,ATG16L1,DIRAS3,PSMD4,HNRNPL,GJA1,PRMT5,OPTN,RIT1,STYK1,HSP90AA1,EXOC8,YWHAZ,ATG3,EXOC2,BECN1,LAMTOR1,OTUD7B,YWHAH,ATG101,YWHAG,ATG7,CSNK2A1,LAMP2 |
| 1.973e-02 | -3.93 | INTS2 (integrator complex subunit 2) | protein interactions | 57508 | 100 | 38 | 19454 | 5460 |
TOP1,HNRNPL,ESR2,APLNR,CDK9,POLR2B,ILVBL,DPEP1,PPP2CB,S1PR4,SCN2B,CD274,INTS12,POLR2F,INTS10,FAS,GPR17,FAM174A,CUL3,SUV39H1,P2RY10,SLC15A1,KDM1A,SEM1,CD80,SSRP1,CD40,VIPR1,EZH2,STK16,SUPT5H,FAM234A,COMTD1,CDC42,PPP2R1A,CLEC2B,SOX2,HCST |
| 1.973e-02 | -3.93 | MUL1 (mitochondrial E3 ubiquitin protein ligase 1) | protein interactions | 79594 | 100 | 38 | 19454 | 5460 |
SUMO1,TP53,UBE2W,TRAF2,EHD1,BZW2,CXCR4,MAVS,AKAP1,APPBP2,UBE2D3,HSCB,RIGI,GABARAP,SLC5A6,GPR17,SLC25A46,EDEM1,VPS26A,UBE2E2,SCN3B,AKT1,UBE2E3,UBE2D1,MUL1,HTRA2,ATP1A1,GUCY1B1,UBE2G2,UBE2N,LMBR1L,CCNF,UBE2I,ARMC6,RANBP6,MAD2L2,UBE2V2,UBE2L3 |
| 1.975e-02 | -3.92 | CAPN2 (calpain 2) | protein interactions | 824 | 156 | 56 | 19454 | 5460 |
IMMP2L,DUSP19,DCP2,PSMA1,NAE1,CDK5R1,SNRPE,SOX2,CSTF2T,FNTB,WDR37,B3GNT2,EGLN3,CAV1,SPTAN1,PTPN1,SSU72,SMG8,RPL23,HNRNPA1,COPS5,XPO1,ZDHHC17,NSFL1C,HSPA8,MTDH,STK26,RPA3,PTP4A2,HSP90B1,CFTR,PAFAH1B1,CAPN1,PIP5K1A,UBA3,VIRMA,BCCIP,DYRK1A,STAT2,GMDS,GAS2,MSN,UBE2I,CCNF,LMBR1L,STUB1,NFKBIA,TUBA1B,UBE2H,CHORDC1,EIF3G,MCM8,BICD2,TUFM,MYC,CSK |
| 1.980e-02 | -3.92 | positive regulation of cysteine-type endopeptidase activity | biological process | GO:2001056 | 131 | 50 | 18204 | 5365 |
BCL2A1,JAK2,BCL2L1,NLRP2,BAD,DAP,CRADD,PMAIP1,MCL1,ANP32B,NLRP3,IFT57,FAS,HTRA2,HSPE1,RPS27L,ARL6IP5,CTSD,FIS1,PPARG,IFI16,MUL1,BOK,SMAD3,ACVR1C,TNF,TNFSF10,RPS3,MIR15A,EGLN3,CYFIP2,DAPK1,CLEC7A,BAK1,BAX,MYC,TNFSF15,AIFM1,HSPD1,BCL10,FAM162A,NLRP1,PDCD5,HMGB1,SYK,FASLG,KHDC1,PYCARD,S100A8,NKX3-1 |
| 1.981e-02 | -3.92 | human chr14q13.2 | chromosome location | human chr14q13.2 | 11 | 6 | 26134 | 5823 |
BRMS1L,INSM2,PSMA6,SRP54,NFKBIA,FAM177A1 |
| 1.982e-02 | -3.92 | GIGYF1 (GRB10 interacting GYF protein 1) | protein interactions | 64599 | 175 | 62 | 19454 | 5460 |
CRTC2,TNRC6C,YTHDF2,KIF1C,STARD13,DNAJB4,ZC3H7A,TESK2,LSM14A,GARRE1,TCEA2,SRSF12,ENKD1,RIGI,TRIM37,YWHAH,CPEB1,YWHAG,XPO1,EDC3,FEM1B,ANKRD10,MOV10,CNOT2,CAMSAP2,YWHAB,TIAM1,EIF4E2,FUBP3,CNTROB,EGLN3,NUP35,KCTD3,PRNP,SIPA1L1,WDR83,INPP5E,ATG16L1,AGAP1,CSNK1A1,MMADHC,FAM53C,MNS1,RNF113A,SNRPA,RTKN,RBM22,DEPDC1B,MAP3K21,TBC1D1,SNRPB,SFN,FAM110B,CEP85,GRB10,STAC3,TBC1D25,ARMC7,YWHAZ,SCNM1,SH3BP4,REEP3 |
| 1.984e-02 | -3.92 | HIT-like | gene3d domains | 3.30.428.10 | 9 | 6 | 14470 | 4137 |
HINT2,APTX,FHIT,HINT3,CWF19L1,HINT1 |
| 1.984e-02 | -3.92 | paz domain | gene3d domains | 2.170.260.10 | 9 | 6 | 14470 | 4137 |
PIWIL4,PIWIL3,AGO1,PIWIL1,DICER1,PIWIL2 |
| 1.984e-02 | -3.92 | organelle disassembly | biological process | GO:1903008 | 134 | 51 | 18204 | 5365 |
RETREG3,ATG3,PELO,FBXO7,ABCE1,VRK1,GABARAPL1,TAFAZZIN,MAP1LC3A,EIF4E2,ATG7,MTRES1,GABARAPL2,FUNDC2,UFM1,ATG4C,ATG9A,RIMOC1,BECN1,RETREG2,UFL1,FIS1,RETREG1,RNF14,TP53,SKIC8,DDRGK1,ATG4A,PLAAT3,STX5,FAF2,FBXL4,TEX264,USP30,GFM2,RCHY1,CTSK,RRP7A,EIF2D,CDK1,MAP1LC3B,RB1CC1,TRIP4,TRIM21,FUNDC1,WDR45,MAP4,SQSTM1,GABARAP,PHB2,HDAC6 |
| 1.987e-02 | -3.92 | PPP1R12B (protein phosphatase 1 regulatory subunit 12B) | protein interactions | 4660 | 58 | 24 | 19454 | 5460 |
PSMD14,PPP2R1A,ISCU,PPP1CB,CTNNB1,PPP1CC,CD14,PIK3R3,E2F4,NOTCH2,ASB1,TNKS2,SKP1,ESR2,ASB3,VIRMA,SPPL3,PPP1R27,GMDS,LRRC1,HSPA8,TNKS,PPP1R12A,IMPACT |
| 1.987e-02 | -3.92 | DLGAP5 (DLG associated protein 5) | protein interactions | 9787 | 58 | 24 | 19454 | 5460 |
CDK1,RPA2,TUBB4B,TRIM36,KBTBD4,MRPL12,TRAF2,TRIM37,B2M,PSMA5,ZYX,BAG2,MAPRE1,MYC,H2BC9,FBXO7,DYRK1A,EGLN3,TUBA1B,RAN,RSRC1,CCNF,OPTN,CORO1C |
| 1.987e-02 | -3.92 | HIC2 (HIC ZBTB transcriptional repressor 2) | protein interactions | 23119 | 58 | 24 | 19454 | 5460 |
PNMA2,CTBP1,EP300,S100B,FOXP2,FOXP4,UFL1,CEP70,DDRGK1,E4F1,RUNX1,FOXA3,CUL3,FOXP1,CALU,TEX19,CRBN,FBLN5,TBCCD1,APEX1,VIRMA,EGLN3,MIF,TMED9 |
| 1.987e-02 | -3.92 | sars9b (ORF9b protein) | protein interactions | 1489679 | 58 | 24 | 19454 | 5460 |
RPS20,GTF2F2,AP2M1,STUB1,PEG10,TOMM70,TRIR,VTI1B,BAG3,RPS17,XPO1,CAMSAP2,AP2A1,CHORDC1,MAVS,FHL3,HSPA8,LSM14A,RADX,PSMA2,PSMC4,AP2S1,DTWD2,MAD2L1BP |
| 1.987e-02 | -3.92 | FLI1 (Fli-1 proto-oncogene, ETS transcription factor) | protein interactions | 2313 | 58 | 24 | 19454 | 5460 |
HAPSTR1,EWSR1,SMARCD3,PIAS1,RIGI,SS18,TGFBR2,EGR2,SOX2,ACTL6A,TP53,PAX9,SMARCB1,IRF8,UBE2I,ETV6,SMAD3,ELK1,SPPL3,KLF1,SIAH1,SMARCE1,SMAD9,BRCA1 |
| 1.987e-02 | -3.92 | INTS8 (integrator complex subunit 8) | protein interactions | 55656 | 58 | 24 | 19454 | 5460 |
CRELD1,EZH2,KLRD1,MGARP,PPP2R1A,HCST,SUPT5H,SSRP1,NPTN,KRAS,SEM1,HAX1,LAMP3,CDC5L,ESR2,POLR2B,POLR2I,TOP1,HNRNPL,IL2RA,POLR2F,INTS10,LMBR1L,S100A6 |
| 1.989e-02 | -3.92 | GLA_1 | prosite domains | PS00011 | 14 | 8 | 12186 | 3388 |
F2,PRRG1,MGP,F10,PROS1,F9,BGLAP,F7 |
| 1.989e-02 | -3.92 | GLA_2 | prosite domains | PS50998 | 14 | 8 | 12186 | 3388 |
F9,BGLAP,PROS1,F10,F7,PRRG1,F2,MGP |
| 1.990e-02 | -3.92 | neurotransmitter transport | biological process | GO:0006836 | 140 | 53 | 18204 | 5365 |
CDK5,SLC6A7,ICA1,STX1A,CPLX3,WNT7A,SLC6A1,SLC1A3,SNAP25,SLC6A11,STX11,SNAP29,LIN7B,SLC6A12,PPT1,NLGN1,KCNJ10,RIMS3,SLC6A3,RIMS4,SLC18B1,PPFIA3,SYT2,RAP1A,ASIC1,SLC1A2,SLC1A1,SLC6A2,HRH3,DNAJC5,CPLX1,SNAP23,SLC6A6,RAB3A,PSEN1,ATP1A2,SYT4,NAPA,SLC6A8,SV2B,LIN7C,SLC29A1,STXBP1,SLC6A4,VAMP2,CLN8,SYN3,KCNJ8,CPLX2,SLC38A2,SLC38A1,SNAPIN,SLC32A1 |
| 1.991e-02 | -3.92 | mitotic cell cycle phase transition | biological process | GO:0044772 | 146 | 55 | 18204 | 5365 |
CDKN1A,WNT10B,RBBP8,CHMP2A,MNAT1,CUL2,RB1,EZH2,PIM2,RPL24,CCNF,TAF2,CUL3,CDKN1B,PPM1D,PLCB1,DNM2,CKS2,CDK4,CCNA2,CCNB1,ARPP19,UBE2S,ANAPC2,PIAS1,CDKN3,CCND1,ABCB1,CDC23,LCMT1,TAF10,CCNY,CCND3,CCNI,ID4,TMOD3,MYC,CACUL1,EIF4E,CDK1,HSPA8,TPD52L1,RHOU,ACVR1B,PPME1,CDC7,PPP3CA,UBE2A,EPS8,CDK6,FBXL7,HINFP,CKS1B,MTA3,BTN2A2 |
| 1.991e-02 | -3.92 | mitochondrial gene expression | biological process | GO:0140053 | 143 | 54 | 18204 | 5365 |
MRPL33,QRSL1,MRPL50,TFB1M,MRPL47,MRPL20,TUFM,MRPS16,MRPS33,MRPL41,MTG1,MRPL18,FASTKD5,MRPL22,MTRF1,MRPL49,MRPL52,MRPS21,MRPL36,MRPS23,MRPL57,MRPL9,MRPS25,MRPL10,MRPS18B,MRPS17,MRPS9,MRPL12,MRPL13,MRPL24,GFM2,TWNK,TRMT5,MRPL53,MRPS18C,MRPS26,CHCHD1,MRPL16,MRPL40,HSD17B10,MRPS28,GFM1,MRPL23,MRPS34,MRPS11,MRPS18A,MTERF2,MRPL17,MRPL51,MRPL34,MRPL11,MRPS35,MRPS7,AURKAIP1 |
| 1.992e-02 | -3.92 | ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase) | protein interactions | 27 | 97 | 37 | 19454 | 5460 |
BAG2,HSPA8,JAK1,OIP5,KIT,EPHA4,KRAS,SPR,GTF3C4,CDC42,FGFR1,CRKL,TPD52L1,MET,HRAS,BST2,RAC2,RHOJ,GPX1,HSP90AB1,VIRMA,NCKAP1,MDM2,MAD2L1,PIK3R3,SFN,SIVA1,AR,YWHAH,YWHAG,BICD2,NCK1,SHC1,YWHAZ,YWHAB,CBL,HSP90AA1 |
| 1.992e-02 | -3.92 | SS18L1 (SS18L1 subunit of BAF chromatin remodeling complex) | protein interactions | 26039 | 97 | 37 | 19454 | 5460 |
ACTL6A,SMAD1,MED30,EGR2,SKA3,SSBP3,HGS,ELF5,SMARCB1,FOS,ATF3,SMARCD3,BCL7B,EP300,RLIM,MIA2,FAM168A,MAPK1IP1L,USP30,PAX6,AATF,PCGF6,SS18,CUL3,ZMYND19,MYC,CREBBP,SNRPB,SMARCE1,BCL7C,BRD3,SMAD3,BRD9,GATAD1,SF3B4,LGALS3,ESR2 |
| 1.992e-02 | -3.92 | RHEB (Ras homolog, mTORC1 binding) | protein interactions | 6009 | 97 | 37 | 19454 | 5460 |
PSEN2,RPA3,SQSTM1,RAB9A,APPBP2,RABAC1,TRIM63,SRPRB,SLC15A1,KRAS,TNF,BNIP3L,DUSP19,FKBP8,PSEN1,RAP1A,LAP3,RAF1,TRAF2,MAP1LC3B,RELL2,RPA2,PDE6D,ITGB8,PHB1,HRAS,NUDT9,SPPL3,UBB,LDHB,MYC,LAMP2,CREB3,GNG2,RNF152,RIT1,VPS4A |
| 1.992e-02 | -3.92 | LIN7C (lin-7 homolog C, crumbs cell polarity complex component) | protein interactions | 55327 | 97 | 37 | 19454 | 5460 |
SLC31A1,NF2,EPHA4,KRAS,BCL7B,BAP1,DLG1,HSPA8,EFNB1,EZH2,PALS2,ADAMTS1,CAPZA2,MTMR2,CASK,KBTBD4,TP53,CFTR,YES1,DUSP10,ESR2,DLG4,DLGAP4,INTS12,ANKRD49,TIAM1,NTRK3,SLC20A1,UBE2H,MYC,LIN7B,WWP2,RIOX2,XPO1,DNAJC5,PPP1CC,SPATA2 |
| 1.992e-02 | -3.92 | ATP13A2 (ATPase cation transporting 13A2) | protein interactions | 23400 | 97 | 37 | 19454 | 5460 |
LRP6,NPY1R,HDAC6,LAMP2,ICAM2,SCN3B,FUNDC2,WDR83OS,APEX1,MARCHF4,POPDC2,TMEM74,CYGB,SEC61B,ACKR3,CD79B,CIB2,FAM8A1,SLC4A8,CRELD1,VAMP2,GP9,PCMTD2,TOP3B,WDR5B,TMED7,BNIP3L,FKBP8,CMTM6,HSPA8,RAB9A,PDIA6,RAB5A,YIF1A,SPCS2,CXCR4,TSPAN15 |
| 1.994e-02 | -3.92 | DCAF15 (DDB1 and CUL4 associated factor 15) | protein interactions | 90379 | 252 | 86 | 19454 | 5460 |
PLS3,DCUN1D5,PTS,BUD23,ARFGAP1,DSTYK,ROCK2,TRIM37,KRAS,LASP1,CCT8,SCYL2,ZYX,NCK1,PDAP1,NQO1,CBL,UBFD1,DCAF4L2,TOR4A,HMG20A,WDR44,EGLN3,PPIA,CORO1C,GTF2IRD1,FEM1A,LMBRD2,EIF4B,TOR1AIP2,PSMB3,ETF1,SLC31A1,LYPLA2,PYM1,NMRAL1,SAT1,DCAF4,CKB,RMI1,RIT1,MLF2,JPT1,ATXN1L,EFHD2,DDIT4,POLR2G,HBP1,TOR3A,TCOF1,MAP1B,PPP1R12A,HINT1,PC,SEPTIN7,TCEAL9,MAP4,USP15,CDK12,ZNF24,GMPPA,DBT,EHBP1,HCLS1,PSMB1,ACACA,EIF3J,WSB1,CD2AP,PPP1R2,YKT6,UGP2,RBM23,DDX46,SNCG,SQSTM1,LCP1,MTDH,RNF34,UHMK1,DTL,CHMP5,RAPGEF5,TENT2,CTTN,MID1IP1 |
| 1.994e-02 | -3.92 | CXCR4 (C-X-C motif chemokine receptor 4) | protein interactions | 7852 | 252 | 86 | 19454 | 5460 |
VKORC1L1,ABHD12,B4GAT1,NDUFAF4,JAK2,STAT1,RALA,STAT2,RHOJ,SLC1A1,GPR89A,INTS12,CD79B,SELENOT,FAM91A1,NRP1,NTRK3,REEP6,GGCX,ATP1A3,SNX14,RHOB,ST13,USP14,LRRC8C,VEZT,RETSAT,TM9SF4,PTPN11,GCNT3,B2M,LPAR1,HMGB1,HSPA8,HADHA,RNF113A,CXCR4,LRP10,TBC1D17,LEMD3,LMBRD2,SIGMAR1,SEC62,CDC42,RND2,SLC19A2,NOP9,TLCD4,CAV1,ADCK1,TNFSF18,MYBL2,RAC2,CD4,SDC4,RHOG,MUL1,EXOC2,P2RY10,EXOC1,WDR11,MZT2B,ORC5,DPP4,FAR2,CXCL12,TMEM208,RIGI,VPS16,LPCAT3,USP30,EFNB1,JAK1,CCR5,OSTM1,UQCC2,OTULIN,EXOC3,KLRC2,PTRH2,YIPF3,DDX39A,SOCS3,TMEM59,DSTYK,METTL15 |
| 1.999e-02 | -3.91 | PWP2 (PWP2 small subunit processome component) | protein interactions | 5822 | 131 | 48 | 19454 | 5460 |
RPA3,SIRT7,EXOSC4,MTDH,WDR3,ZNF692,UFL1,B9D2,HSCB,STAU1,RPL4,CFTR,RPA2,RPS3,FGFBP1,RPL13A,SMURF1,TOM1L1,ESR2,MYC,CUL3,MECP2,ATG3,ZBTB38,DNAJB6,RIT1,UBE2H,FGF3,RPS24,KRAS,IMP3,TP53,RPL15,CHMP4C,EED,FZR1,SURF6,CEP19,GRSF1,IFI16,WWP2,XPO1,DDRGK1,MPHOSPH10,CHCHD1,DNAJC7,MPHOSPH6,BRD3 |
| 1.999e-02 | -3.91 | KCTD9 (potassium channel tetramerization domain containing 9) | protein interactions | 54793 | 223 | 77 | 19454 | 5460 |
SPMIP9,SYNCRIP,HSP90AB1,NUP35,CCT7,EGLN3,TCP1,PPP1R18,SMUG1,CRADD,GAPDH,XPO1,HNRNPA1,PGAM1,PFDN5,FKBP4,DHX9,PICK1,HNRNPA2B1,CCT8,ZBTB25,HSPD1,STX11,CSE1L,VDAC1,HNRNPK,PSMA1,EEF2,SPG21,ACTN4,TUBA1A,KLHL26,SMARCB1,ILF2,ZMAT2,TRIM27,ENO1,CDPF1,TUBA1B,LMBR1L,MAD2L2,TUBB,LDHA,MATR3,ATP5F1B,KCTD9,GORASP2,ATP5F1A,NTAQ1,CUL3,LDHB,PSMB2,TRIM32,HSP90AA1,NRP1,ATP1A1,LMNB1,YWHAZ,CCT2,CKB,NIF3L1,DDX5,HSPA8,RCCD1,XRCC5,ACTMAP,HSPA5,SKP1,SPMIP6,NDUFAB1,EHHADH,DDIT4L,WDR83,SPTBN1,HOXB8,ZBTB42,SDCBP |
| 2.006e-02 | -3.91 | Telomere Maintenance | REACTOME pathways | R-HSA-157579 | 82 | 35 | 10285 | 3229 |
POLA2,RUVBL1,H2AZ1,POLE4,H2AZ2,H2AB1,POLD4,H2AC7,RFC2,H2BC14,RPA2,H2BC11,POLD2,H2AJ,RUVBL2,FEN1,H2BC17,H2AX,RFC3,H2AC4,H2BC12,WRAP53,DKC1,RFC5,RPA3,NHP2,RFC4,PRIM2,H2BC9,H2AC6,H2BC1,H2AC14,POLE3,TERT,PCNA |
| 2.006e-02 | -3.91 | Photodynamic therapy-induced NF-kB survival signaling | WikiPathways | WP3617 | 35 | 19 | 5310 | 1910 |
TRAF6,BIRC2,IKBKB,CCND1,IL2,CD40LG,TNF,IL1A,MMP9,NFKB1,VEGFA,CXCL8,EGLN2,IL1B,BIRC5,CSF2,BCL2A1,ICAM1,IL6 |
| 2.010e-02 | -3.91 | NME2P1 (NME2 pseudogene 1) | protein interactions | 283458 | 94 | 36 | 19454 | 5460 |
SLC25A44,TPD52,DUSP22,SOX2,NME1,CHMP4C,DISC1,HSD17B6,P2RY12,TUBB4B,RDH12,EP300,GPM6B,RNF133,ANAPC16,SGF29,SKP1,RNF26,CHRNA7,VAMP5,GPR171,MORF4L1,LRAT,CABCOCO1,NFYA,CASP4,ARL6IP6,COPS5,NFKBIA,DUSP6,DDIT4,GTF2B,MGST3,NPC2,EFNA5,MBD5 |
| 2.010e-02 | -3.91 | WWC1 (WW and C2 domain containing 1) | protein interactions | 23286 | 94 | 36 | 19454 | 5460 |
DLG1,MAEA,DDR1,LIN7C,NF2,H3C1,KRAS,STXBP1,USP6NL,CSNK1E,PRKCA,FEM1A,GSK3A,FEZ1,KIAA0513,AIFM1,TNIK,VIRMA,APEX1,CDC5L,LRIF1,SLC25A31,DYNLL1,DAG1,YWHAH,YWHAG,XPO1,SAV1,CDKN3,MOV10,FAM219A,YWHAB,ARMC8,CDC73,PIP4K2C,FBXW11 |
| 2.010e-02 | -3.91 | ACSF2 (acyl-CoA synthetase family member 2) | protein interactions | 80221 | 94 | 36 | 19454 | 5460 |
FAHD1,MRPL23,ACTB,RAMP3,SUCLG2,APEX1,WDR44,MTG2,CREB3,FAM174A,MRM2,COMMD5,PCCB,GMPS,GSTO1,TAFAZZIN,PPTC7,RDH10,MAIP1,HSPD1,SLC25A10,AMACR,RASL10B,RIGI,PCK2,H1-5,AGTRAP,NDUFAB1,CCS,MRPL12,LDHAL6B,RPA2,ACAA2,AQP3,NUDT16,SYNGR3 |
| 2.011e-02 | -3.91 | human chr7q32.2 | chromosome location | human chr7q32.2 | 20 | 9 | 26134 | 5823 |
SSMEM1,UBE2H,MIR335,TMEM209,MIR183,CEP41,MIR96,MEST,MIR182 |
| 2.012e-02 | -3.91 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_essential_thrombocythaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_essential_thrombocythaemia | 29 | 14 | 16828 | 4835 |
CALR,RUNX1,SF3B1,CBL,IDH1,HRAS,KRAS,EZH2,PTEN,IDH2,JAK2,SRSF2,TP53,KIT |
| 2.012e-02 | -3.91 | acute_leukaemic_transformation_of_essential_thrombocythaemia | COSMIC cancer mutations | acute_leukaemic_transformation_of_essential_thrombocythaemia | 29 | 14 | 16828 | 4835 |
CALR,RUNX1,SF3B1,CBL,IDH1,HRAS,KRAS,EZH2,PTEN,IDH2,JAK2,TP53,SRSF2,KIT |
| 2.012e-02 | -3.91 | acute_leukaemic_transformation_of_polycythaemia_vera | COSMIC cancer mutations | acute_leukaemic_transformation_of_polycythaemia_vera | 29 | 14 | 16828 | 4835 |
EZH2,PTEN,IDH2,JAK2,PTPN11,SRSF2,TP53,KIT,SF3B1,RUNX1,CBL,IDH1,KRAS,HRAS |
| 2.012e-02 | -3.91 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_polycythaemia_vera | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_polycythaemia_vera | 29 | 14 | 16828 | 4835 |
IDH2,PTPN11,JAK2,SRSF2,TP53,KIT,EZH2,PTEN,CBL,IDH1,KRAS,HRAS,SF3B1,RUNX1 |
| 2.012e-02 | -3.91 | lactation | biological process | GO:0007595 | 39 | 18 | 18204 | 5365 |
CCND1,SLC29A1,CREB1,VEGFA,VDR,UPRT,SOCS2,UMPS,STAT5A,OXTR,PRL,GJA1,CAV1,SLC6A3,CDO1,DDR1,NME1,APLN |
| 2.015e-02 | -3.90 | MYBL2 (MYB proto-oncogene like 2) | protein interactions | 4605 | 153 | 55 | 19454 | 5460 |
EWSR1,KRAS,ASF1A,MRPL22,PHF1,PAX6,MTA3,TOP3B,E2F4,SOX2,MAP1LC3B,SAP30,CBX3,RPN1,IRF8,VPS33A,EZH2,PNMA2,MTA2,SIN3A,CTDSPL2,MYBL2,EED,GATAD1,SHPRH,BRMS1L,TRIM15,EGLN3,CDK9,NUF2,DPY30,CXCR4,EP300,MBD3,COIL,SPTBN1,H1-5,CCND1,CCNA2,CPSF1,CCNF,PHF12,EIF4A3,EZH1,ZMYM2,ZNF622,SNRNP40,RBBP4,CDC20,UBB,CREBBP,SMARCA5,MYC,OST4,RIT1 |
| 2.015e-02 | -3.90 | SRM (spermidine synthase) | protein interactions | 6723 | 61 | 25 | 19454 | 5460 |
HDAC6,FBXO7,COPS5,MOV10,MYC,UBE2H,PDAP1,AGR2,NT5DC1,DUSP6,CCNF,LMBR1L,PRNP,MAP1LC3B,DUSP1,CDC42,UBE2M,RPA2,RPRD1B,EFHC1,ABCE1,RPA3,DUSP9,DUSP19,SRM |
| 2.015e-02 | -3.90 | MYL9 (myosin light chain 9) | protein interactions | 10398 | 61 | 25 | 19454 | 5460 |
FBXO25,TRIM37,FOXD3,MYL6,HEXIM1,TFCP2,CFTR,MYL12B,TP53,B3GNT2,DYRK1A,MYL12A,TES,EIF2S2,OPTN,FOXP1,HSPB1,SP1,CBL,PIP4K2C,HDAC6,BTF3,MYC,MICB,AKT3 |
| 2.015e-02 | -3.90 | EMP1 (epithelial membrane protein 1) | protein interactions | 2012 | 61 | 25 | 19454 | 5460 |
RPRM,CD3G,CLDN9,SYNE4,SERTM1,TLCD4,LRRC3B,TSPO2,PMP22,OPRM1,CEP70,BTN2A2,TMEM114,TMEM160,CCR5,TEX264,RABAC1,ATP6V0B,LEPROTL1,EHHADH,ATP6V0E1,LPAR6,STOM,TMEM31,MS4A7 |
| 2.015e-02 | -3.90 | TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3) | protein interactions | 257397 | 61 | 25 | 19454 | 5460 |
TAB1,CEP57L1,ETV6,TRIM27,BICD2,TRAF6,BECN1,YWHAZ,IKBKB,UBE2H,USP15,SFN,WWP2,IFI16,EMILIN1,YWHAH,YWHAG,RBCK1,TNF,AKAP1,TRIM5,NLRP6,TAB2,PPIL3,TRAF2 |
| 2.015e-02 | -3.90 | PRKG1 (protein kinase cGMP-dependent 1) | protein interactions | 5592 | 61 | 25 | 19454 | 5460 |
LMO2,AR,NGDN,SPP1,PPP1R17,HSPB1,CREB1,TNIK,PSMC5,TRIM54,SELL,WDR77,RAF1,GKAP1,KIF2A,CFTR,CBX3,PRKCA,ANXA7,MACROH2A2,PPP1R12A,ZKSCAN1,LASP1,GTF2I,RGS2 |
| 2.015e-02 | -3.90 | ICMT (isoprenylcysteine carboxyl methyltransferase) | protein interactions | 23463 | 61 | 25 | 19454 | 5460 |
VIPR1,PRKCB,HAPSTR1,JAGN1,RPA3,GCA,KRAS,DUSP1,CCDC47,OXSR1,RPN1,RPA2,AQP3,RAC2,HRAS,CCNF,ELK1,APEX1,TRIM32,RELL1,CUL3,PDZK1IP1,ARMC8,UBE2H,SLC2A1 |
| 2.015e-02 | -3.90 | MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3) | protein interactions | 23162 | 61 | 25 | 19454 | 5460 |
DCTN4,MAP2K1,KLC2,RAF1,TOP3B,TP53,MAP2K3,MAPK10,TNKS2,BCL6,MAP3K11,TLR4,RCCD1,DCTN6,TLR2,DCTN3,EP300,TLR9,ZNF575,HNRNPL,AKR1C2,BTG3,SRC,ARL4D,TNKS |
| 2.015e-02 | -3.90 | HES1 (hes family bHLH transcription factor 1) | protein interactions | 3280 | 61 | 25 | 19454 | 5460 |
TLE1,GAPDH,HDAC6,YWHAB,ID1,HSP90AA1,FBXL14,RB1,HEY2,SPTAN1,JAK2,CSNK1E,NUDT3,LMO3,ID4,LMNA,HEXIM1,PRKCA,RBPJ,LTBR,ZFP64,HMGB1,APH1A,FANCG,SKP1 |
| 2.015e-02 | -3.90 | MAPK15 (mitogen-activated protein kinase 15) | protein interactions | 225689 | 61 | 25 | 19454 | 5460 |
HSP90AA1,CCT2,FKBP4,ST13,CSK,CACYBP,PPP5C,HSP90AB1,SRC,GANAB,TIMM8B,HSP90B1,DDX39A,GABARAPL1,MAP1LC3B,TIMM13,TIMM8A,TGFB1I1,GABARAP,RIGI,PTGES3,B2M,HSPA8,CDK5,PCNA |
| 2.023e-02 | -3.90 | nucleotide transmembrane transport | biological process | GO:1901679 | 31 | 15 | 18204 | 5365 |
LRRC8A,SLC25A5,SLC25A31,LRRC8D,SHOC2,SLC25A17,SLC25A51,LRRC8C,SLC25A23,LRRC8B,SLC25A4,SLC25A24,SLC25A32,SLC35B3,SLC25A42 |
| 2.023e-02 | -3.90 | pyrimidine nucleotide biosynthetic process | biological process | GO:0006221 | 31 | 15 | 18204 | 5365 |
UCK2,UMPS,CMPK1,PRPS1,DTYMK,DCK,TYMS,UPRT,AK5,NME4,NME2,UCKL1,UCK1,SHMT1,NME1 |
| 2.023e-02 | -3.90 | positive regulation of sodium ion transport | biological process | GO:0010765 | 31 | 15 | 18204 | 5365 |
MLLT6,CNKSR3,CNTN1,PRSS8,SCN3B,ACTN4,AKT1,CHP1,AHCYL1,ATP1B1,TESC,SCN1B,ATP1B3,FGF12,FGF13 |
| 2.023e-02 | -3.90 | positive regulation of cell-substrate junction organization | biological process | GO:0150117 | 31 | 15 | 18204 | 5365 |
MAPRE2,PIK3R1,SDC4,DUSP3,SMAD3,NRP1,POLDIP2,ROCK1,ARF6,FERMT2,S100A10,SFRP1,VEGFA,IQSEC1,THY1 |
| 2.023e-02 | -3.90 | cellular response to interleukin-4 | biological process | GO:0071353 | 31 | 15 | 18204 | 5365 |
CDK4,STAT5A,IL2RG,HSP90AB1,MRC1,STAT6,NFIL3,TUBA1B,XCL1,IL4,JAK1,RPL3,PML,HSPA5,XBP1 |
| 2.024e-02 | -3.90 | NRSN1 (neurensin 1) | protein interactions | 140767 | 172 | 61 | 19454 | 5460 |
JUP,IDH2,FGFR1,MET,CLSTN3,BET1,FUT8,ARHGAP1,PAQR3,IL1RAP,ST8SIA4,LRP10,LCP1,EGFL7,BET1L,TMEM106C,DNAJB6,MLF1,BAG3,TRIM29,TAX1BP1,B4GALT3,NDFIP1,UBB,TOM1L1,VAMP3,KLK6,LRP12,CALML5,STX10,MACROH2A1,TMEM59L,BMPR2,ACVR1,STX12,SDR16C5,FURIN,HGS,MTCH2,SERPINA3,TMEM59,LGR4,IFNGR1,RNF115,SLC20A2,TF,EFNB1,MAN1A2,AGR2,CHST11,C2CD2L,FCGR1A,HSPB8,FATE1,TOR1B,PRELID1,STX6,EXTL2,B4GALT6,EXT1,LDLR |
| 2.025e-02 | -3.90 | ER Quality Control Compartment (ERQC) | REACTOME pathways | R-HSA-901032 | 22 | 12 | 10285 | 3229 |
EDEM1,OS9,RNF139,UBA52,RPS27A,SYVN1,UBB,EDEM3,EDEM2,DERL2,RNF103,RNF5 |
| 2.026e-02 | -3.90 | FKBP10 (FKBP prolyl isomerase 10) | protein interactions | 60681 | 91 | 35 | 19454 | 5460 |
HSPA5,GRPEL1,CHCHD2,EMC1,IGF1R,EMC2,DDX5,HSPA8,TMEM106B,DNAJC3,BAP1,PPME1,CCL18,P3H1,H2AX,PPP2R1A,CDC42,MGARP,TP53,GTF2H4,STRBP,B3GNT2,TMCC2,TAX1BP1,SEC61B,ELSPBP1,LMBR1L,UQCRC2,CALU,LANCL2,DNAJC5,GGH,FAM163B,CFC1,MYC |
| 2.026e-02 | -3.90 | TMEM259 (transmembrane protein 259) | protein interactions | 91304 | 91 | 35 | 19454 | 5460 |
TMUB1,SRPRB,ADRB2,TNF,RNF5,TMEM106B,B3GALT2,SLC25A3,PCLAF,DIPK1A,ERLIN2,OTULINL,TMUB2,YIPF3,OR4N2,TOP3B,ERLIN1,TNFSF18,ST3GAL5,ANKRD46,LHFPL1,COPE,GPR173,APOC4,S1PR4,LMBR1L,BCL2L1,SLC35C1,STYK1,TYROBP,ATP1B3,ATP1B1,EMC6,EDEM1,TMEM199 |
| 2.026e-02 | -3.90 | ACVR1B (activin A receptor type 1B) | protein interactions | 91 | 91 | 35 | 19454 | 5460 |
OS9,SMURF1,PEG10,ACVR1C,RHOJ,MANSC1,SNX2,SNX1,SPINT2,SLC1A1,SMAD3,TSNAX,SMAD2,ZDHHC15,TMEM30A,HSP90AA1,RHOB,SMAD4,PRKACB,ICAM2,GPBAR1,VPS16,CLDND1,ACVR1B,TGFBR2,GPR83,TSPAN17,RHOU,TSPAN3,IL20RB,FKBP1A,ACVR1,BMPR2,RELL2,PGRMC1 |
| 2.026e-02 | -3.90 | KRT33B (keratin 33B) | protein interactions | 3884 | 91 | 35 | 19454 | 5460 |
PLEKHJ1,BCL10,USP15,ICA1,USP2,CUL3,ATG9A,YWHAG,SHC3,MB21D2,PPP1R18,NDN,ZBTB2,DES,SCNM1,INPP5K,KRT8,FAAP100,YBEY,HAPLN2,EZH2,FRS3,ZER1,HGS,GSTP1,HEXIM1,FASLG,EFHD1,CFTR,LMO4,KDM1A,SGF29,DUSP21,ARFIP1,RAMAC |
| 2.026e-02 | -3.90 | HLA-DPB1 (major histocompatibility complex, class II, DP beta 1) | protein interactions | 3115 | 91 | 35 | 19454 | 5460 |
C2CD2,ST3GAL5,SLC25A4,IDE,ZMYND19,VSTM2A,TMEM106C,ATP1A3,SPCS3,SMPD2,HFE,YPEL5,ARMC8,TMEM160,CHST10,FSTL1,GID4,GID8,TMEM106B,MAEA,MKLN1,TAPBP,HECTD3,ERP29,SQSTM1,RTN4,RANBP10,FKBP2,SSBP2,TIMMDC1,LGR4,RARRES2,TCP11L1,SFTPC,SOST |
| 2.027e-02 | -3.90 | positive regulation of viral process | biological process | GO:0048524 | 64 | 27 | 18204 | 5365 |
DHX9,PPID,HACD3,TOP2B,HMGB1,TRIM21,CD4,PPARA,STOM,PPIH,TMEM39A,FURIN,CNOT7,SRPK2,VAPB,CD209,CCL5,KPNA2,TSG101,TRIM11,VPS4A,PPIA,PDE12,PABPC1,KPNA6,STAU1,CD28 |
| 2.027e-02 | -3.90 | regulation of multicellular organism growth | biological process | GO:0040014 | 64 | 27 | 18204 | 5365 |
HDAC3,ZMPSTE24,GHRL,ADRB3,HTRA2,NPY1R,PPIB,PLAC8,GHR,ADRB1,GAMT,FXN,ADRB2,STAT5A,SOD1,PIK3CA,SLC6A3,DIO3,MBD5,NPPC,MKKS,FOXS1,CREB1,FOSL2,GH1,GPAM,SOCS2 |
| 2.027e-02 | -3.90 | neuron cellular homeostasis | biological process | GO:0070050 | 64 | 27 | 18204 | 5365 |
IFNB1,DISC1,NELL2,ATP6V1A,CACNB2,ATP6V1G2,CX3CL1,IL6,CHMP2B,CACNB4,BAP1,SLC6A2,SNAPIN,TMEM106B,HEXB,P2RY1,ATP6V1C1,P2RY4,ATP6AP2,ADORA1,ATP6V1G1,CA2,ATP6V1D,SV2B,CNR1,PSEN1,DNAJB2 |
| 2.033e-02 | -3.90 | TMEM67 (transmembrane protein 67) | protein interactions | 91147 | 128 | 47 | 19454 | 5460 |
PSMC4,GP9,CST11,SPCS2,AKAP1,EMC1,ST8SIA4,HSPA5,RAB2A,CUL3,PSMD1,SPCS3,SDF2L1,PSMD14,NSA2,CD1E,PSMC5,NDP,PSMD4,ATP6AP2,CCDC47,PREB,CLEC2B,ERLIN2,RPN1,NRN1,SIGLECL1,SFTPC,PSMC3,SEC11A,EMC2,CD1B,SLC6A8,TMEM199,CFC1,SCGB1D1,HM13,ATP1B1,MSMB,TMEM30A,ELSPBP1,SRPRA,CAMLG,DEFB121,HSD17B11,CD1A,DUOXA2 |
| 2.034e-02 | -3.89 | dysembryoplastic_neuroepithelial_tumour | COSMIC cancer mutations | dysembryoplastic_neuroepithelial_tumour | 9 | 6 | 16828 | 4835 |
IDH2,PTEN,IDH1,TERT,TP53,KRAS |
| 2.034e-02 | -3.89 | acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | COSMIC cancer mutations | acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | 9 | 6 | 16828 | 4835 |
KRAS,HRAS,KIT,PTPN11,JAK2,RUNX1 |
| 2.034e-02 | -3.89 | pancreas-ampulla_of_Vater-carcinoma | COSMIC cancer mutations | pancreas-ampulla_of_Vater-carcinoma | 9 | 6 | 16828 | 4835 |
HRAS,STK11,KRAS,PIK3CA,JAK2,AKT1 |
| 2.034e-02 | -3.89 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | 9 | 6 | 16828 | 4835 |
RUNX1,PTPN11,JAK2,KRAS,KIT,HRAS |
| 2.034e-02 | -3.89 | glucagonoma | COSMIC cancer mutations | glucagonoma | 9 | 6 | 16828 | 4835 |
HRAS,KRAS,CTNNB1,SMAD4,CDKN2C,PTEN |
| 2.034e-02 | -3.89 | pancreas-carcinoid-endocrine_tumour-glucagonoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-glucagonoma | 9 | 6 | 16828 | 4835 |
SMAD4,CDKN2C,PTEN,HRAS,CTNNB1,KRAS |
| 2.034e-02 | -3.89 | skin-mucosal-malignant_melanoma-nodular | COSMIC cancer mutations | skin-mucosal-malignant_melanoma-nodular | 9 | 6 | 16828 | 4835 |
PIK3CA,GNAQ,KRAS,HRAS,GNA11,KIT |
| 2.034e-02 | -3.89 | skin-upper_leg-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-upper_leg-malignant_melanoma-superficial_spreading | 9 | 6 | 16828 | 4835 |
IDH1,IDH2,KIT,HRAS,KRAS,CTNNB1 |
| 2.034e-02 | -3.89 | skin-ear-benign_melanocytic_nevus-melanocytic_tumour | COSMIC cancer mutations | skin-ear-benign_melanocytic_nevus-melanocytic_tumour | 9 | 6 | 16828 | 4835 |
KIT,HRAS,GNA11,AKT1,BAP1,GNAQ |
| 2.036e-02 | -3.89 | modulation by host of viral process | biological process | GO:0044788 | 50 | 22 | 18204 | 5365 |
PC,IFI27,ZBED1,CAV2,ROCK2,RAB29,PAIP1,NUCKS1,CDC42,PHB1,ZDHHC8,RAB5A,HSPA8,PPIB,MIR222,CCL8,EEF1A1,PSMC3,MIR221,STOM,CFL1,APOBEC3H |
| 2.037e-02 | -3.89 | MAP3K10 (mitogen-activated protein kinase kinase kinase 10) | protein interactions | 4294 | 64 | 26 | 19454 | 5460 |
DLG4,PHB1,COPS2,TUBB,KIF3B,CYP4F12,HSP90AB1,SMURF1,SFN,TSPO,RACGAP1,YWHAG,MAP3K21,HPCA,YWHAH,YWHAZ,CYP11B2,YWHAB,SPHK2,HSP90AA1,DDR1,PIK3R2,RIGI,HPCAL1,CDC42,HGS |
| 2.037e-02 | -3.89 | CNOT4 (CCR4-NOT transcription complex subunit 4) | protein interactions | 4850 | 64 | 26 | 19454 | 5460 |
UBE2E3,UBE2D1,YWHAB,CNOT2,YWHAH,XPO1,CNOT8,YWHAG,ESR2,UBE2N,CNOT6,PTEN,TRIM24,AP2M1,UBE2B,LMNA,UBE2W,YTHDF2,CNOT7,UBE2D3,CNOT6L,LSM14A,RNF113A,EP300,ELOF1,ZC3H7A |
| 2.037e-02 | -3.89 | AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2) | protein interactions | 10555 | 64 | 26 | 19454 | 5460 |
AQP3,GP9,SIGMAR1,RPA2,CAV2,TOP3B,COMTD1,HPCAL1,H1-3,SEC62,RNF5,TUSC2,HSPA8,SLC2A8,TSPAN17,VIPR1,TMEM70,ATP1A3,SLC2A1,TNFSF13,GPBAR1,GMPS,APLNR,RAMP3,SLC23A2,SLC1A1 |
| 2.037e-02 | -3.89 | DUSP12 (dual specificity phosphatase 12) | protein interactions | 11266 | 64 | 26 | 19454 | 5460 |
CFAP298,RAB28,DFFA,HRAS,DUSP3,SRC,HDDC2,NR1H2,MBLAC2,HSPB8,TMEM208,VPS4A,PSMD10,NCK1,LACRT,TMEM11,RABAC1,HSPD1,EIF2D,PHYKPL,PTN,CCNH,TPT1,TMEM126A,AKR7A2,RPA2 |
| 2.037e-02 | -3.89 | LRCH2 (leucine rich repeats and calponin homology domain containing 2) | protein interactions | 57631 | 64 | 26 | 19454 | 5460 |
RPAP3,RCCD1,PSME1,TULP3,CDC42,GABRA1,RPAP2,RND3,ARPC3,FEM1A,VPS33A,GSK3A,CCNF,EGLN3,PRNP,MIF,DAPK1,USP14,COPS5,YWHAH,H2BC9,UBE2H,MYO6,FBXW11,BICD2,CRLF3 |
| 2.037e-02 | -3.89 | PDZK1 (PDZ domain containing 1) | protein interactions | 5174 | 64 | 26 | 19454 | 5460 |
USP3,AKT1,SLC1A3,SLC6A6,SLC15A2,CRHR1,PDZK1IP1,SLC19A3,UBE2I,DECR2,SLC22A12,KCTD3,APEX1,ASNSD1,CFTR,NHERF1,SH2D5,OTULIN,SLCO1A2,KLHL24,KCTD17,KRAS,ZBED1,ABCC2,SLC5A6,ZBTB5 |
| 2.039e-02 | -3.89 | response to starvation | biological process | GO:0042594 | 213 | 77 | 18204 | 5365 |
UCP2,RRAGA,SLC2A1,YWHAG,ALB,HCRT,HNRNPA1,TP53,IGF1R,LAMP2,GLUL,SFRP1,FLCN,CTSK,SESN3,TRIM32,GNPAT,GPT,KICS2,BGLAP,COMT,UGT1A1,MAP1LC3B,HSPA8,KLF10,DELE1,HFE,MIOS,RALB,ATF3,FOXA3,GABARAP,DDIT3,ATF4,WDR45,TFEB,PPARA,RNF167,NFE2L2,FOS,RRAGB,PCSK9,CDKN1A,SH3GLB1,SAR1B,MAP1LC3A,FBXO22,SLC38A2,GABARAPL1,PMAIP1,RNF152,EIF2S1,BMPR2,DAP,STK24,IMPACT,HSPA5,GABARAPL2,XBP1,PPM1D,ATG7,PCK2,TBC1D5,CBL,YWHAZ,SLC38A3,SESN2,SUV39H1,FAS,EIF2AK2,STK26,PICK1,IFI16,SP1,BECN1,ACAT1,CARTPT |
| 2.040e-02 | -3.89 | MGMT (O-6-methylguanine-DNA methyltransferase) | protein interactions | 4255 | 88 | 34 | 19454 | 5460 |
PRKCA,RNF8,TUBB4B,CDK1,EEF1A1,CDKN1A,SSRP1,PTPN4,PCNA,DDX5,RNF113A,EP300,HNRNPA2B1,PRPF4,DTL,HSP90AA1,CDK12,UBE2H,YWHAZ,CSNK2A1,MCM3,CREBBP,HNRNPC,CCNB1,UBB,ESR2,HSP90AB1,SLC25A4,ACTB,TOP1,RPLP1,EEF1B2,PSME2,PHB1 |
| 2.040e-02 | -3.89 | PDGFB (platelet derived growth factor subunit B) | protein interactions | 5155 | 88 | 34 | 19454 | 5460 |
RPF2,MDFI,PIK3R1,MRPS35,FBXO7,FTSJ3,NRP1,PDAP1,COL1A2,NSA2,MRPS9,RPS3,HRAS,MRPL13,MRPL50,DKC1,MDM2,MALSU1,BCCIP,MRPL47,RPL15,RBM34,RPL26L1,MRPL51,NKAPD1,COL3A1,MRPS33,RPS15,NOP53,NOC4L,ADIPOQ,MRPS18C,UTP23,BRIX1 |
| 2.040e-02 | -3.89 | CCNL2 (cyclin L2) | protein interactions | 81669 | 88 | 34 | 19454 | 5460 |
GNAZ,ACACA,GNAQ,PRKCA,CDK7,EHD1,MND1,SAP30BP,GNB4,PYGB,CNTN1,NF2,CCNY,NSDHL,GNA11,CBR3,BRD3,ZCRB1,BRCA1,TUFM,PRKACB,ANAPC15,CSNK2A1,SAMHD1,MDFI,DYRK1A,SRC,IREB2,CSTF3,YES1,SNX1,SPPL3,IRF2BP1,CSNK2B |
| 2.040e-02 | -3.89 | GCDH (glutaryl-CoA dehydrogenase) | protein interactions | 2639 | 88 | 34 | 19454 | 5460 |
RHOH,RHOJ,PRNP,EGLN3,LMBR1L,SSBP1,TACO1,OPTN,CCNF,TES,GATD3,SNRNP70,SLC25A28,MRPS26,CUL3,PMPCA,MTRF1,MYC,MTG2,AUH,ADRB2,HSCB,IMMP2L,PSEN1,PSEN2,RPA3,COX8A,GFM1,RNF113A,HAPSTR1,HINT2,PDHA1,CFTR,FAF2 |
| 2.046e-02 | -3.89 | human chr6p21.1 | chromosome location | human chr6p21.1 | 98 | 31 | 26134 | 5823 |
MAD2L1BP,MDFI,MEA1,TOMM6,DLK2,CDC5L,XPO5,SLC29A1,PTCRA,TSPO2,LRRC73,VEGFA,OARD1,RPL7L1,MIR586,YIPF3,FRS3,HSP90AB1,FOXP4,CCND3,DNPH1,TFEB,GNMT,MRPS18A,GTPBP2,SUPT3H,NFYA,PTK7,CNPY3,ENPP4,TREML1 |
| 2.050e-02 | -3.89 | Spinal Cord Injury | WikiPathways | WP2431 | 119 | 54 | 5310 | 1910 |
RTN4,PTPRZ1,CHST11,TNF,IL1A,MIR23B,CDKN1B,PRKCA,CXCL10,FCGR2A,FKBP1A,IFNG,LEP,EPHA4,PLA2G5,AQP4,MYC,TNFSF13,CDK4,CDC42,PPP3CA,LTB,CXCL8,RGMA,TP53,FOS,RB1,ROCK2,CDK1,ICAM1,GJA1,IL2,MMP9,CD47,GADD45A,APEX1,BTG2,IL4,SOX9,RHOB,OMG,CXCL1,AIF1,IL1B,LGALS3,TLR4,MIF,CCND1,TACR1,PDYN,CCR2,CCL2,EGR1,IL6 |
| 2.051e-02 | -3.89 | SYCE2 (synaptonemal complex central element protein 2) | protein interactions | 256126 | 19 | 10 | 19454 | 5460 |
TEX12,NAP1L5,DDX39A,TRIM27,GAD2,CRLF3,MED11,HOMER1,MED4,TSNAX |
| 2.051e-02 | -3.89 | DRC12 (dynein regulatory complex subunit 12 homolog) | protein interactions | 283152 | 19 | 10 | 19454 | 5460 |
NUP62,CDR2L,DDIT3,STX5,GORASP2,SPG21,PSMA1,GUCD1,CDR2,GNMT |
| 2.051e-02 | -3.89 | INPP4A (inositol polyphosphate-4-phosphatase type I A) | protein interactions | 3631 | 19 | 10 | 19454 | 5460 |
VIRMA,NXT2,HNRNPL,LDLR,SMAD1,CD81,NTAQ1,CAPN1,CUL3,PIK3R1 |
| 2.051e-02 | -3.89 | KCNG1 (potassium voltage-gated channel modifier subfamily G member 1) | protein interactions | 3755 | 19 | 10 | 19454 | 5460 |
KCNS1,DDX39A,TOP3B,KCNA2,KCNB1,UBB,HSP90AA1,TMED7,TLR9,MARCHF4 |
| 2.051e-02 | -3.89 | RIMS2 (regulating synaptic membrane exocytosis 2) | protein interactions | 9699 | 19 | 10 | 19454 | 5460 |
ZDHHC15,RAB3A,RIMS3,RAB3B,RABAC1,YWHAH,RAB27A,RAB3C,MYC,RAB3D |
| 2.051e-02 | -3.89 | C14orf178 (chromosome 14 open reading frame 178) | protein interactions | 283579 | 19 | 10 | 19454 | 5460 |
GTF2E1,BTF3,PRMT5,POLR3B,PELO,NDUFA2,WDR77,RPL10,CDK12,KDM1A |
| 2.051e-02 | -3.89 | REX1BD (required for excision 1-B domain containing) | protein interactions | 55049 | 19 | 10 | 19454 | 5460 |
SMN1,RIGI,OSGEP,PSMD14,PSMD7,TRIM63,GPRASP2,MDFI,AKT1,PSMD3 |
| 2.051e-02 | -3.89 | VPS37D (VPS37D subunit of ESCRT-I) | protein interactions | 155382 | 19 | 10 | 19454 | 5460 |
HGS,VPS28,ARMC7,P3H1,RBCK1,CRTAP,TSG101,TRAF2,PPIB,SAV1 |
| 2.051e-02 | -3.89 | TMEM234 (transmembrane protein 234) | protein interactions | 56063 | 19 | 10 | 19454 | 5460 |
CREB3,ADRA1A,UNC50,TMEM107,TMEM203,LMNA,FAM241B,VTI1B,CXCL9,SLC35E3 |
| 2.051e-02 | -3.89 | CPLANE1 (ciliogenesis and planar polarity effector complex subunit 1) | protein interactions | 65250 | 19 | 10 | 19454 | 5460 |
VIRMA,SRPK2,RPA2,CAND1,SOX2,HAPSTR1,NEK2,TESK2,S100B,AUH |
| 2.051e-02 | -3.89 | RPAIN (RPA interacting protein) | protein interactions | 84268 | 19 | 10 | 19454 | 5460 |
UBR7,GSTA1,CYP17A1,CUL3,APEX1,OXSR1,FBXW7,RPA2,HNRNPL,KRAS |
| 2.051e-02 | -3.89 | Mtx1 (metaxin 1) | protein interactions | 17827 | 19 | 10 | 19454 | 5460 |
FXR2,P3H1,CAMK2G,WWP1,TAF11,TOP3B,ATP5MG,TMEM263,RRAS2,SEC61A1 |
| 2.051e-02 | -3.89 | ATP5MC3 (ATP synthase membrane subunit c locus 3) | protein interactions | 518 | 19 | 10 | 19454 | 5460 |
ATP5IF1,FAM241A,MOV10,ATP5MC3,RIGI,ESR2,KRAS,TMEM31,ATP5F1B,ATP5F1D |
| 2.051e-02 | -3.89 | ASB11 (ankyrin repeat and SOCS box containing 11) | protein interactions | 140456 | 19 | 10 | 19454 | 5460 |
PSMB2,GANAB,ELOC,RPN1,PSMA2,ATP5F1B,RNF7,ERLIN1,PSMC3,PRPS1 |
| 2.051e-02 | -3.89 | RWDD4 (RWD domain containing 4) | protein interactions | 201965 | 19 | 10 | 19454 | 5460 |
MOB3C,ZBTB2,KCTD17,BRCA1,BTF3,DDX39A,XPO1,FBXO7,ZNF330,CUL3 |
| 2.051e-02 | -3.89 | SPINK7 (serine peptidase inhibitor Kazal type 7) | protein interactions | 84651 | 19 | 10 | 19454 | 5460 |
BIRC2,MAEA,GID8,IDE,UBB,MT2A,FTL,ARMC8,ZER1,HBA1 |
| 2.051e-02 | -3.89 | RCVRN (recoverin) | protein interactions | 5957 | 19 | 10 | 19454 | 5460 |
CAV1,GIT2,HIKESHI,IL15RA,TOP1,TGFBR2,ARL4D,RAB9A,PQBP1,SMAD3 |
| 2.051e-02 | -3.89 | ZPR1 (ZPR1 zinc finger) | protein interactions | 8882 | 85 | 33 | 19454 | 5460 |
AHCYL1,UBE2A,KRAS,HNRNPF,UFM1,PSMA3,ZYX,RPA3,FKBP1A,ZBTB42,FKBP10,KLC2,PPME1,ACTR2,RPRD1B,VPS4B,P3H1,ABHD5,ETF1,EEF1A1,UBE2L3,UBE2V2,TOM1L1,HYPK,TES,SURF2,SRXN1,RIT1,OSGEP,FAS,UBE2D1,VPS26A,CDC123 |
| 2.052e-02 | -3.89 | GOT1 (glutamic-oxaloacetic transaminase 1) | protein interactions | 2805 | 262 | 89 | 19454 | 5460 |
PITPNA,LMNA,RPA2,JUP,ARHGAP1,SYNGR2,BCL6,YKT6,LCP1,BAP1,SOD1,RPA3,TPPP3,UBE2H,OAT,SERPINB1,PIP4K2C,CHRAC1,CHCHD4,GLOD4,DDAH2,SNX3,RAB14,CCR2,MACROH2A1,ALB,PITPNB,CALML5,ELOVL4,CRABP2,NECAP2,CMPK1,RIGI,TF,HSPE1,PC,AGA,IDH1,CD9,NME2,MOV10,MAPRE2,PLG,MTAP,ALDH1A3,DUSP14,H1-5,CDSN,NT5C3A,OXCT1,RAB5A,TXNL1,MDH1,HTRA2,ICAM1,BLVRA,CAPG,HMGCS1,GFUS,TXNRD2,PYCARD,SFN,F2,NIBAN2,ESR2,LGALS3,TRIM29,AKR1C2,ENO2,CYB5R3,SRXN1,SDR16C5,NME1,PIR,EZH2,SERPINA3,CCS,PPIL3,RBBP9,UFM1,NQO1,RPL6,CRIP1,NUP35,FAHD1,TYMS,WDR82,S100A8,PSME2 |
| 2.052e-02 | -3.89 | ZHX2 (zinc fingers and homeoboxes 2) | protein interactions | 22882 | 67 | 27 | 19454 | 5460 |
MTHFD2L,PML,RBBP7,PAX6,KLF12,ELF1,KLF3,PAX9,HRAS,AIFM1,ZHX3,ELK3,VRTN,ZHX1,CSNK2B,HNRNPL,SNRNP40,RBBP4,USP38,VIRMA,ESR2,NFYA,USP13,NFKB1,YWHAZ,ABITRAM,LHX2 |
| 2.052e-02 | -3.89 | ISOC2 (isochorismatase domain containing 2) | protein interactions | 79763 | 67 | 27 | 19454 | 5460 |
HSCB,NME4,LSM8,SELENOO,DNLZ,RAB6B,IDH2,ACAA2,GTPBP1,PIH1D1,SOD2,ELP3,DDX39A,LGALS3,PPIA,ENO1,CCNF,IFT172,FAHD1,DSTN,CLDN3,VASH1,TST,UPK1A,MOV10,AK3,CFL1 |
| 2.052e-02 | -3.89 | TMEM80 (transmembrane protein 80) | protein interactions | 283232 | 67 | 27 | 19454 | 5460 |
BET1,CCDC167,SMCO4,FAM3C,TMEM243,CLDN8,TLCD1,GPR37L1,STX7,FKBP8,TMEM107,ARL6IP6,FAM20B,CLDN11,DOLK,TMEM100,ADGRE2,RPRM,TMEM14A,CD63,SYNGR1,SLC66A2,CYBC1,TVP23B,VKORC1L1,TSPO2,AIG1 |
| 2.052e-02 | -3.89 | POGLUT2 (protein O-glucosyltransferase 2) | protein interactions | 79070 | 67 | 27 | 19454 | 5460 |
ITGB8,P3H1,RPA2,SPSB3,TMEM106A,CBLN4,ATG16L1,LY6H,HSPA5,KRAS,GPIHBP1,MAP3K11,RPA3,TMEM106B,CALU,TAFAZZIN,LCN6,GGH,CUL2,CUL3,MSTN,LYZL6,DNAJB9,BMP1,DNASE1L1,SEC61B,ELSPBP1 |
| 2.052e-02 | -3.89 | KRTCAP2 (keratinocyte associated protein 2) | protein interactions | 200185 | 67 | 27 | 19454 | 5460 |
STT3A,INTS12,PLAGL1,TMPO,RBM42,RMND1,OST4,RAB2A,CREB3,TIA1,SLC30A5,RAP2B,POR,DRG1,REEP6,PLSCR1,CXCR4,RABAC1,HSCB,DAD1,CERS6,FKBP8,LPCAT3,PGRMC1,RPN1,PICALM,SCLT1 |
| 2.052e-02 | -3.89 | AHDC1 (AT-hook DNA binding motif containing 1) | protein interactions | 27245 | 67 | 27 | 19454 | 5460 |
CRTAP,COP1,WWP2,AR,SNRNP40,HNRNPL,DAPK1,NUP35,VIRMA,ESR2,CBX5,LRIF1,CSRNP1,GSK3A,ADNP,CHAMP1,CBX3,TRIM68,DOK5,TOP3B,IKZF5,EGR2,SOX2,DDX39A,RPL4,ZDHHC17,PML |
| 2.055e-02 | -3.88 | PRKCE (protein kinase C epsilon) | protein interactions | 5581 | 150 | 54 | 19454 | 5460 |
SORD,H1-1,HSP90AA1,SERPINB1,YWHAZ,SFN,VIRMA,SRC,PRKCE,TUBB,SLC25A4,STAT1,SRP54,TUBA1B,TSSK1B,BAD,SLC25A3,PRKCA,CFTR,PCK2,LAP3,BCL6,TOMM20,HSPA8,PRKCB,MYH2,HSPB1,YWHAB,FKBP4,TIAM1,IKBKB,YWHAG,HSP90AB1,G6PD,NTMT1,PRKCQ,HNRNPL,KRT8,GJA1,GDI2,TUBB4B,BPIFA2,RAF1,SERPINB9,RIGI,RPS27A,VDAC1,THRAP3,RASGRP3,AKAP12,NEDD8,ZBTB16,GAD2,SLC25A5 |
| 2.056e-02 | -3.88 | C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone | KEGG pathways | M00109 | 6 | 5 | 7161 | 2463 |
CYP17A1,HSD11B1,CYP11B2,CYP11B1,CYP21A2 |
| 2.056e-02 | -3.88 | C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone | KEGG pathways | hsa_M00109 | 6 | 5 | 7161 | 2463 |
CYP11B2,CYP17A1,HSD11B1,CYP11B1,CYP21A2 |
| 2.057e-02 | -3.88 | PPP1R37 (protein phosphatase 1 regulatory subunit 37) | protein interactions | 284352 | 38 | 17 | 19454 | 5460 |
HRAS,RAB35,RAB5A,RAB9A,KRAS,STX7,STX6,ATG9A,ZMYND19,MYC,CALR,ATG16L1,RAB11A,PPP1CB,TFRC,LAMTOR1,RAB4A |
| 2.057e-02 | -3.88 | AGR3 (anterior gradient 3, protein disulphide isomerase family member) | protein interactions | 155465 | 38 | 17 | 19454 | 5460 |
DESI1,ESR2,ERLIN1,PTPN1,HSD17B10,SGTA,EDA2R,CGRRF1,CD46,TMEM14B,PDZK1IP1,TIMMDC1,NUP62,AKT1,DAG1,NRM,NTAQ1 |
| 2.057e-02 | -3.88 | MXD3 (MAX dimerization protein 3) | protein interactions | 83463 | 38 | 17 | 19454 | 5460 |
MAX,NFKB1,NUP62,ZMYM3,SAP30,BRMS1,ASPM,MXD1,SERPINH1,SAP30L,TFIP11,SIN3A,ING2,BRMS1L,APEX1,MXI1,EDEM2 |
| 2.057e-02 | -3.88 | CDH13 (cadherin 13) | protein interactions | 1012 | 38 | 17 | 19454 | 5460 |
HDAC6,AGPAT5,DSTYK,MYC,CCND1,HAX1,CDH13,RPL23,VMP1,SEC14L1,TMX4,GHITM,PTPN1,MDC1,RRAGB,ADIPOQ,GPM6A |
| 2.057e-02 | -3.88 | CDC123 (cell division cycle 123) | protein interactions | 8872 | 38 | 17 | 19454 | 5460 |
TPM3,UTP6,USP14,XPO1,CUL3,HSPB1,UBE2M,DNAJC7,RPA2,EIF2S2,HRAS,RHOU,RPA3,CEP19,EGLN3,MED17,HSCB |
| 2.057e-02 | -3.88 | STK33 (serine/threonine kinase 33) | protein interactions | 65975 | 38 | 17 | 19454 | 5460 |
RB1CC1,HAX1,HSP90AA1,CALU,USP15,SDF2L1,STIM1,MGARP,CNP,PHKA1,CSK,HSP90AB1,USP5,CLPB,BAG2,PHKB,EFNA3 |
| 2.057e-02 | -3.88 | NUDT18 (nudix hydrolase 18) | protein interactions | 79873 | 38 | 17 | 19454 | 5460 |
TRIM37,KCTD17,CAVIN2,ZBED1,NAT9,GNMT,COIL,GLUL,RWDD1,TIFA,RABAC1,DCTD,DHPS,KXD1,NT5C2,PCBD1,TRAF2 |
| 2.057e-02 | -3.88 | HEPACAM2 (HEPACAM family member 2) | protein interactions | 253012 | 38 | 17 | 19454 | 5460 |
CERK,UGCG,FGFR1,LGR4,CYB5R1,PIK3R3,RAB18,RDH11,MAD2L2,WDR44,EDEM2,PIK3R2,ACVR1B,NDFIP1,LRP10,EHD4,BMPR1A |
| 2.057e-02 | -3.88 | GSS (glutathione synthetase) | protein interactions | 2937 | 38 | 17 | 19454 | 5460 |
GBE1,USP14,YWHAG,YWHAH,ZFAND6,SMAD4,YWHAB,BAP1,LDLR,MSN,HSPA8,PAFAH1B2,RRAGB,PPP5C,CDK9,GINS3,OLA1 |
| 2.057e-02 | -3.88 | OAZ1 (ornithine decarboxylase antizyme 1) | protein interactions | 4946 | 38 | 17 | 19454 | 5460 |
RIGI,RNF20,ODC1,LDLR,AZIN1,OAZ3,PSMB4,ACTA2,AZIN2,CAMSAP2,OAZ1,SMAD1,OAZ2,PGM2L1,YWHAG,GBE1,MYC |
| 2.057e-02 | -3.88 | ZNF800 (zinc finger protein 800) | protein interactions | 168850 | 38 | 17 | 19454 | 5460 |
RNF113A,PRKRA,RPL23A,KRR1,VIRMA,VPS16,ESR2,MBD3,CNTROB,DGCR8,RPS10,TM9SF4,MTA3,RPL10A,MTA2,HBP1,MECP2 |
| 2.057e-02 | -3.88 | RORA (RAR related orphan receptor A) | protein interactions | 6095 | 38 | 17 | 19454 | 5460 |
CSNK1E,CREBBP,PROX1,COPS5,LMO3,EZH2,NME2,PNRC1,NR0B1,NME1,SP1,SMARCD3,PRMT5,PSMC5,EP300,RUVBL1,LRIF1 |
| 2.057e-02 | -3.88 | USP51 (ubiquitin specific peptidase 51) | protein interactions | 158880 | 38 | 17 | 19454 | 5460 |
GSTA1,CDK6,SGF29,DGCR8,MDM2,CDK4,ENY2,TAF5L,CD2AP,LBR,H1-3,PRMT2,H2AC4,TADA3,TADA1,USP15,SUPT7L |
| 2.057e-02 | -3.88 | USP45 (ubiquitin specific peptidase 45) | protein interactions | 85015 | 38 | 17 | 19454 | 5460 |
POLR2G,RBM7,MYL6,CDK1,CFL1,H2BC9,SMAD1,MYC,BMPR1B,MYL12B,PPP5C,SMURF1,TMOD3,NOP53,PIK3CG,CSNK2B,CORO1C |
| 2.057e-02 | -3.88 | ISL2 (ISL LIM homeobox 2) | protein interactions | 64843 | 38 | 17 | 19454 | 5460 |
ORC6,EIF1AD,PICK1,RNF187,BCL9,SSBP2,LMO2,COPS7A,SOX2,LDB1,SSBP4,COPS5,EGR2,LMO4,LMO3,SSBP3,LHX2 |
| 2.057e-02 | -3.88 | Pcbp1 (poly(rC) binding protein 1) | protein interactions | 23983 | 38 | 17 | 19454 | 5460 |
RALYL,MRPL10,RBFOX2,DDX50,TNFAIP3,YWHAZ,APOBEC3C,CTBP1,PTEN,PRR3,RBM3,PNO1,CCNF,SNRPA,SRSF12,RPS13,WDR3 |
| 2.057e-02 | -3.88 | PHF23 (PHD finger protein 23) | protein interactions | 79142 | 38 | 17 | 19454 | 5460 |
BRMS1L,RBBP4,HMGB1,TRIM63,RBBP7,KLF9,VTA1,SIN3A,EP300,SF3B1,HSP90B1,RIT1,REN,PRSS23,STK11,TBK1,SAP30 |
| 2.057e-02 | -3.88 | KANK1 (KN motif and ankyrin repeat domains 1) | protein interactions | 23189 | 38 | 17 | 19454 | 5460 |
PRNP,DYNLL1,VIRMA,CA10,ENO1,SYT2,GSK3A,YWHAZ,MYO6,H1-1,YWHAB,NDC80,AKT1,MOV10,EDC3,YWHAG,YWHAH |
| 2.058e-02 | -3.88 | Ubiquitin mediated proteolysis | KEGG pathways | ko04120 | 137 | 59 | 7161 | 2463 |
CUL3,COP1,TRIM37,CDC16,UBE2F,CDC20,UBE2N,KLHL9,SYVN1,UBE2E2,UBE2A,CBL,FZR1,UBE2B,MDM2,BIRC2,TRIM32,RHOBTB1,UBE3A,UBE2M,WWP2,FBXW11,UBE2W,DET1,UBE2H,PRPF19,CDC26,SOCS3,CUL2,ANAPC11,WWP1,UBE2G2,UBE2S,ANAPC13,STUB1,HERC3,RNF7,SKP1,ANAPC2,SIAH1,CDC23,TRAF6,UBE2D3,RCHY1,UBA3,HUWE1,SMURF1,PML,PIAS1,FBXW7,UBE2L3,HERC4,ANAPC4,UBE2I,BRCA1,ELOC,UBE2E3,UBE2D1,UBE2K |
| 2.058e-02 | -3.88 | Ubiquitin mediated proteolysis | KEGG pathways | hsa04120 | 137 | 59 | 7161 | 2463 |
BIRC2,MDM2,UBE2B,TRIM32,RHOBTB1,UBE2M,WWP2,UBE3A,UBE2W,FBXW11,DET1,UBE2H,PRPF19,CDC26,SOCS3,CUL3,COP1,TRIM37,CDC16,UBE2F,CDC20,SYVN1,KLHL9,UBE2N,UBE2E2,UBE2A,CBL,FZR1,PML,SMURF1,PIAS1,FBXW7,HERC4,UBE2L3,UBE2I,ANAPC4,ELOC,BRCA1,UBE2K,UBE2D1,UBE2E3,ANAPC11,CUL2,WWP1,UBE2S,UBE2G2,ANAPC13,STUB1,HERC3,RNF7,SKP1,CDC23,ANAPC2,SIAH1,TRAF6,UBE2D3,HUWE1,UBA3,RCHY1 |
| 2.060e-02 | -3.88 | MRM2 (mitochondrial rRNA methyltransferase 2) | protein interactions | 29960 | 82 | 32 | 19454 | 5460 |
ARMC8,BRCA1,MRPL16,PCCB,ZMYND19,CLPX,MTG2,IDE,MALSU1,MANSC1,TMEM74,FAHD1,MGME1,CRAT,CNP,MRPL12,PI15,NDUFA2,RANBP10,TSPAN5,RIGI,FTL,POLDIP2,SLC31A1,MKLN1,HECTD3,HSPD1,PREPL,GID4,BCKDK,GID8,MAEA |
| 2.060e-02 | -3.88 | PPIL2 (peptidylprolyl isomerase like 2) | protein interactions | 23759 | 82 | 32 | 19454 | 5460 |
SPPL3,SNRNP40,CDC5L,CCNF,LMBR1L,PRCC,ZNF330,RBBP8,DDX23,LMNB1,TRIM23,HSP90AA1,PIM2,RIT1,MYC,YWHAH,PPIB,SNRPB,H3C1,KRAS,STAU1,COIL,RPL31,PML,EP300,VPS26B,PPIH,LMNA,CDK8,CBX3,KLC2,ACACA |
| 2.061e-02 | -3.88 | 1433_2 | prosite domains | PS00797 | 7 | 5 | 12186 | 3388 |
YWHAH,YWHAZ,YWHAB,SFN,YWHAG |
| 2.061e-02 | -3.88 | GS | prosite domains | PS51256 | 7 | 5 | 12186 | 3388 |
ACVR1,BMPR1A,ACVR1C,ACVR1B,BMPR1B |
| 2.061e-02 | -3.88 | 1433_1 | prosite domains | PS00796 | 7 | 5 | 12186 | 3388 |
YWHAZ,YWHAH,YWHAG,SFN,YWHAB |
| 2.062e-02 | -3.88 | ALCAM (activated leukocyte cell adhesion molecule) | protein interactions | 214 | 70 | 28 | 19454 | 5460 |
CD81,RAB2A,RAB5C,CDC73,OSGEP,LGALS8,CD9,RHOB,SOSTDC1,HRAS,RAB35,DIRAS3,HNRNPL,ALCAM,THAP8,ARF6,LGALS3,SYK,PAQR3,PDCD1LG2,CYB5B,HSPA8,RAB9A,ITGA2,RAB5A,STX7,KRAS,VDAC1 |
| 2.062e-02 | -3.88 | AXIN2 (axin 2) | protein interactions | 8313 | 70 | 28 | 19454 | 5460 |
SMAD1,ANKRD6,FAM161A,CHIC2,TOP3B,FBP1,CSNK1E,PRKCA,RNF146,FBP2,RLIM,TCEA2,AP1M1,STX11,TNKS2,FXR2,CTNNB1,H2BC9,PPP2R5A,PRDX1,PSMB2,FBXW11,GSK3A,ZNF189,SCNM1,SMAD3,CDC20,SIAH1 |
| 2.062e-02 | -3.88 | RNF146 (ring finger protein 146) | protein interactions | 81847 | 70 | 28 | 19454 | 5460 |
NF2,UBE2D3,SSRP1,HSPA5,CDC42EP4,TNKS2,XRCC5,MAVS,FHL3,SNAI2,RNF146,PARD6A,NDUFAF3,TRAF2,TUBB,CETN2,UBE2G2,PARP2,LIG3,PTEN,TNKS,SH3BP5L,UBE2D1,UBE2H,STK11,CUL3,ATP5F1A,XPO1 |
| 2.062e-02 | -3.88 | CCZ1 (CCZ1 homolog, vacuolar protein trafficking and biogenesis associated) | protein interactions | 51622 | 70 | 28 | 19454 | 5460 |
PPAT,ABHD17A,CDC5L,EEF1AKMT3,S100A6,SPINT2,DCAF11,FAM174A,LMO2,UBXN6,ETFRF1,ATG7,CDK20,CCIN,TNFSF10,PML,RCCD1,RPA3,THBS3,BAG2,RPA2,RNF181,CAPN2,ATG16L1,RPS14,KBTBD4,CCL3,DET1 |
| 2.062e-02 | -3.88 | H3C7 (H3 clustered histone 7) | protein interactions | 8968 | 70 | 28 | 19454 | 5460 |
RAB3B,ASF1A,RBBP7,H3C1,H1-6,SSRP1,PHF1,MCM6,HIRA,SQSTM1,HMCES,SSR1,PDHA1,RPN1,TRIM36,MTA2,MTA3,BORCS6,UBR7,RBBP4,VIRMA,CBX5,PARP2,LIG3,CCNF,TRIM24,MACROH2A1,MCM4 |
| 2.062e-02 | -3.88 | USP16 (ubiquitin specific peptidase 16) | protein interactions | 10600 | 70 | 28 | 19454 | 5460 |
FBXO11,TXNL1,JAK1,UBE3A,HSPD1,PAX6,SRPRB,STAU1,SATB1,H1-5,RPS11,HGS,RNF8,CDK1,DNAJC2,SOST,LDLR,SEC23A,RPS20,H2AZ1,CCNF,DBT,USP16,G0S2,RPS16,XPO1,MYC,H2AC4 |
| 2.063e-02 | -3.88 | positive regulation of cell differentiation | biological process | GO:0045597 | 906 | 295 | 18204 | 5365 |
CRABP2,IL18,MIR99B,NKAP,FGFR1,OLFM2,AAMDC,GHR,BRINP2,LAMB2,DAG1,LRRC8A,WIF1,MIR140,TIAM1,MDM2,MIR133B,ACTL6B,BRINP1,SDCBP,PAFAH1B1,IFNG,ZC4H2,STK4,CLEC7A,MIR1-1,IL13,MIR34A,SOD2,F11R,IMPACT,TSPO,SLC6A6,NR2E1,AMIGO1,ZNHIT1,FAXDC2,MIR106A,ADIG,CCDC3,LMO3,FZD4,PPARG,NTRK2,NIBAN2,UFL1,SFRP4,CAMK1,BLOC1S5,SHOC2,CTNNBIP1,IL15,S100B,MIR137,EPO,LGALS3,MECP2,SMARCB1,SLITRK1,IL34,MYRF,TGFB1I1,BMPR1A,CYP27B1,SEMA7A,TFE3,VEGFA,IL23A,BMPR2,UPF3B,EZH2,NF2,IL7,PROM1,MME,KCTD11,HMGB1,PITHD1,SYK,KLF10,ACVR1B,SAV1,MACROH2A2,BCL6,CXCL12,HDAC6,TESC,CXCR4,TBC1D24,NME2,DUSP10,STK11,AGER,VSIR,ADIPOQ,TNF,ACTB,PARP2,ATRAID,IL10,SMAD3,CX3CL1,MIR145,RAP1A,CX3CR1,CYB5D2,NKX6-2,TESPA1,TRIM32,CCN3,WNT2,MIR17,NEFL,PRKCA,ZHX3,GJA1,ACVR1,MIR222,TRAF6,NLRP3,FXR2,RARRES2,TLR2,PIAS1,CCL19,EEIG1,RHOH,XRCC5,TRIB1,DISC1,HCLS1,FOS,IL2RA,BMPR1B,NPPC,TERT,RAG1,NFKB1,ILK,IL15RA,RB1,ADNP,MIR424,ZNF365,CD83,PLXNC1,PNP,SASH3,ACTL6A,JUNB,FRZB,FOXP3,HTR2A,TGIF2,NEUROD2,IL6ST,CSF2,HAX1,BTN2A2,SMAD5,KLHL25,STK3,VEGFC,MTCH2,SMARCE1,OPRM1,TMEM100,CXCL9,IL12B,DLX1,MMP14,EPHA4,MIR185,SFRP1,ID4,CREB1,IL6,HAPLN2,FERMT2,MIR142,SOCS2,ASPM,CD86,BTG1,SOCS5,SMURF1,RUNX1,EMP2,TNFRSF1B,SMARCD3,MIR208A,TLR9,PLCB1,BEND6,CREBL2,NPTN,GLIPR2,RGCC,IL4,MIR342,SMAD2,ZBTB16,GPRASP3,SFN,ANAPC2,IGFBP3,MSX2,CPNE1,CD46,LILRB4,MIR146A,MIR519D,EGR2,PTN,MIR21,CD4,SIN3A,SOCS3,PAX6,TYROBP,MAD2L2,WNT10B,MIR204,CD36,PTPRZ1,CD80,CBFB,HSP90AB1,MIR210,CAV3,EFNA5,MIR150,MEF2C,PPP3CA,SOX2,VSTM2A,FAM20C,TGFB3,IL1B,DKK1,AKT1,ISG15,SEMA5A,PRMT5,SMAD4,GPC1,PROX1,EP300,KRAS,IGF1,NOTCH2,LRP3,ASPA,TGFB2,MAP1B,VDR,ADD1,CTNNB1,IL2RG,TOX,MIR20A,XBP1,KIT,SOX9,RHEB,MIR206,FZD3,TGFBR2,IL2,DICER1,MIR221,SNAI2,ADAMTS20,BRINP3,RND2,AR,MMD,JAK2,SMAD1,IL5,MIR200C,PLA2G5,MACROH2A1,NRP1,KDM1A,STAT1,PPP1CC,CCR1,MIR511,MAP2K1,L1CAM,LTA,SETD3,CD34,BAD |
| 2.066e-02 | -3.88 | TSPAN5 (tetraspanin 5) | protein interactions | 10098 | 79 | 31 | 19454 | 5460 |
TSPAN15,PSEN2,TMEM87A,SEC11A,SPCS2,EFNB1,BSCL2,RER1,RDH11,TMUB1,PSEN1,SEC62,ALG11,DDX39A,UBAC2,RDH12,SCAMP2,CYB5R3,GPR89A,B4GALT1,RETREG3,SPCS1,CD47,SC5D,TMEM248,VKORC1L1,SLC38A2,MRM2,KDSR,SLC20A1,DNAJC19 |
| 2.066e-02 | -3.88 | PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3) | protein interactions | 53632 | 79 | 31 | 19454 | 5460 |
CAMK2G,PFDN1,PDRG1,PIP4P1,MSH6,NGRN,CCT8,HSPA8,GNG5,CRYAB,PIP4P2,PRKAB1,CCT5,TUBA1A,TCP1,POLR2B,CACYBP,PDCD5,CCT7,STUB1,ZNF436,CCT2,AJM1,BRCA1,AHSA1,PFDN2,PFDN4,DNAJB6,PFDN6,PFDN5,BAG3 |
| 2.066e-02 | -3.88 | FOSL2 (FOS like 2, AP-1 transcription factor subunit) | protein interactions | 2355 | 79 | 31 | 19454 | 5460 |
IRF2BP1,HNRNPL,KBTBD6,JUNB,VIRMA,TRAF1,LRIF1,CYTH1,BRCA1,TRIB1,COP1,HNRNPC,PRMT6,DPY30,AR,ATF1,TSR3,RIGI,CYTH2,EGR1,FHL3,DDIT3,EP300,FBXO11,HECTD3,NFE2L2,IRF2BPL,POLR2G,TOP3B,DET1,JUN |
| 2.066e-02 | -3.88 | Activation of BAD and translocation to mitochondria | REACTOME pathways | R-HSA-111447 | 15 | 9 | 10285 | 3229 |
YWHAG,BAD,SFN,AKT2,YWHAB,YWHAH,YWHAZ,AKT1,AKT3 |
| 2.066e-02 | -3.88 | NRIF signals cell death from the nucleus | REACTOME pathways | R-HSA-205043 | 15 | 9 | 10285 | 3229 |
RPS27A,UBA52,NCSTN,SQSTM1,PSENEN,UBB,APH1A,PSEN2,TRAF6 |
| 2.068e-02 | -3.88 | ISOC1 (isochorismatase domain containing 1) | protein interactions | 51015 | 73 | 29 | 19454 | 5460 |
MYC,YWHAH,YWHAZ,STK24,AGR2,CKB,UBFD1,DFFA,CCNF,HEBP1,UMPS,G6PD,EGLN3,FERMT2,PAFAH1B1,RAF1,CFTR,CRABP2,TUBB4B,PAK2,RPA2,PITPNA,PIH1D1,UBE2M,PRKCA,RPA3,STK26,PPP1R2,PRCP |
| 2.068e-02 | -3.88 | TMX4 (thioredoxin related transmembrane protein 4) | protein interactions | 56255 | 73 | 29 | 19454 | 5460 |
TMT1A,SYVN1,DERL1,KRAS,TOMM22,CCDC47,OTULINL,TMEM106A,SEC62,ST7,STIM1,RPN1,SSR1,PTPN1,FUT1,HSD17B11,SEC61B,HSD11B1,DNAJC1,DUOXA2,TMPO,CSK,CSGALNACT2,ATP1B3,CD226,TMEM30A,CDH13,TYROBP,CSGALNACT1 |
| 2.068e-02 | -3.88 | STAT2 (signal transducer and activator of transcription 2) | protein interactions | 6773 | 73 | 29 | 19454 | 5460 |
INSYN2A,STAT6,CAPN2,PML,CXCR4,INPPL1,EP300,FBXO11,JAK1,FBXW7,ZNF692,RIGI,SELENOO,CREBBP,IRF9,IFNAR1,INSYN1,XPO1,SMARCE1,SMAD4,HSPB1,PDF,HSP90AA1,KPNA1,DOK4,GSK3A,STAT1,JAK2,ESR2 |
| 2.068e-02 | -3.88 | ERAP1 (endoplasmic reticulum aminopeptidase 1) | protein interactions | 51752 | 73 | 29 | 19454 | 5460 |
MAP2K1,AQP3,TMEM205,CFTR,ZMYM3,EDEM3,CD14,SLC16A10,SIAE,ADRB2,SLC15A1,HSPA8,CXCR4,TMEM87A,TMEM106B,GLUL,MUL1,BRCA1,CCR6,HDAC6,MOV10,GPR17,APLNR,ROMO1,CTSB,YES1,PRNP,SEC61B,ENO1 |
| 2.068e-02 | -3.88 | UBN1 (ubinuclein 1) | protein interactions | 29855 | 73 | 29 | 19454 | 5460 |
EP300,DHX9,HIRA,PML,FOS,RIGI,RBBP7,H3C1,TRIM37,ASF1A,JUN,SPRR1B,MAX,TOP3B,E2F4,E2F6,CDAN1,SMARCB1,CALML5,FABP5,ESR2,VIRMA,CDC5L,PRNP,SNRNP40,MYC,HNF1B,ZCCHC10,CSTA |
| 2.068e-02 | -3.88 | MAP3K2 (mitogen-activated protein kinase kinase kinase 2) | protein interactions | 10746 | 73 | 29 | 19454 | 5460 |
STK38,MAP3K3,NCKAP1,RPS27A,SMURF1,UBB,NFKBIA,LSM14A,STUB1,SQSTM1,TRAF7,CORO1C,BIRC2,YWHAZ,EZH2,YWHAB,STAMBP,HSP90AA1,UBA52,SFN,USP2,STK38L,MCM3,CTNNB1,SMYD3,YWHAG,ACTN4,MAP2K3,YWHAH |
| 2.069e-02 | -3.88 | HNF1A (HNF1 homeobox A) | protein interactions | 6927 | 76 | 30 | 19454 | 5460 |
CBX3,ZMYM4,ELP3,RANBP1,SSRP1,BCL6,HMGB1,SRSF7,EP300,FOS,PEBP1,YWHAB,YWHAZ,SNX14,PCBD1,CTNNB1,YWHAG,TLE1,CREBBP,HNF1B,SMARCA5,RNF14,SRC,SNRPA1,ACTB,SPPL3,LDHA,ALB,ATXN1L,SSBP1 |
| 2.069e-02 | -3.88 | ENDOD1 (endonuclease domain containing 1) | protein interactions | 23052 | 76 | 30 | 19454 | 5460 |
MOV10,HMOX2,CAV3,LAMTOR1,MARCHF3,SSMEM1,ENO1,DPEP1,HRAS,LMBR1L,STARD3NL,CYB5A,EDNRA,HNRNPL,CAV1,SLC19A2,ATG16L1,DDX39A,SOX2,YIPF3,SEC62,CTDSP2,BZW2,STOM,TMEM106B,RTN4,BSCL2,TACR1,RER1,RNF26 |
| 2.078e-02 | -3.87 | feeding behavior | biological process | GO:0007631 | 90 | 36 | 18204 | 5365 |
CNTN2,NPSR1,FOS,USP46,HCRT,NPW,MCHR1,UCN,DRD1,GPR83,OPRL1,OXTR,NPY5R,P2RY1,NEGR1,ADRB3,NPY1R,RMI1,ADM2,GHRL,NPB,HELT,NPY,BRS3,REN,TACR1,DERL2,PEX13,APLN,CNTFR,OPRK1,NTRK2,PPY,HAND2,CARTPT,LEP |
| 2.080e-02 | -3.87 | RNA cap binding complex | cellular component | GO:0034518 | 16 | 9 | 19108 | 5553 |
EIF4E2,OTUD6B,NCBP2,EIF4E3,EIF4EBP3,EIF4A2,EIF4H,EIF4B,EIF4E |
| 2.084e-02 | -3.87 | human chrXq24 | chromosome location | human chrXq24 | 54 | 19 | 26134 | 5823 |
UPF3B,NKRF,UBE2A,TMEM255A,AKAP14,RPL39,WDR44,PGRMC1,NKAP,ZCCHC12,NDUFA1,ZBTB33,SOWAHD,SEPTIN6,MIR1277,C1GALT1C1,SLC25A5,RNF113A,LAMP2 |
| 2.085e-02 | -3.87 | alcohol dehydrogenase (NADP+) activity | molecular function | GO:0008106 | 23 | 12 | 18094 | 5411 |
DHRS4,AKR1B1,DHRS7,RDH12,AKR1A1,AKR1C2,AKR1E2,DHRS3,RDH10,AKR1C1,RDH11,AKR7A2 |
| 2.094e-02 | -3.87 | MSL3 (MSL complex subunit 3) | protein interactions | 10943 | 27 | 13 | 19454 | 5460 |
DDX39A,SOX2,DYRK1B,RHOBTB1,METTL14,CDK6,TUBA1B,MSL2,APEX1,ESR2,ASF1A,POLR2I,H3C1 |
| 2.094e-02 | -3.87 | POLI (DNA polymerase iota) | protein interactions | 11201 | 27 | 13 | 19454 | 5460 |
RIGI,APEX1,RNF11,UBB,NEDD8,EP300,PCNA,HOMER3,DVL2,TRIM23,TRAF6,UBA52,TP53 |
| 2.094e-02 | -3.87 | SFRP2 (secreted frizzled related protein 2) | protein interactions | 6423 | 27 | 13 | 19454 | 5460 |
BMPR1A,MAEA,GID8,CTNNA1,MKLN1,MLH3,EEF1G,CCAR1,ZMYND19,PPP1CB,PPP1CC,SMAD4,ARMC8 |
| 2.094e-02 | -3.87 | SLC2A5 (solute carrier family 2 member 5) | protein interactions | 6518 | 27 | 13 | 19454 | 5460 |
COMT,ATP6V0B,MGST3,TMEM237,RBFOX3,RPSA,SCN3B,ALDH1L1,CCL5,LMBRD2,LMNA,ZMPSTE24,FITM2 |
| 2.094e-02 | -3.87 | OLIG1 (oligodendrocyte transcription factor 1) | protein interactions | 116448 | 27 | 13 | 19454 | 5460 |
NCK1,PSMD14,ID4,DOK5,PIK3R3,HSH2D,MRPL12,STAT5A,YES1,RIGI,DOK4,ELSPBP1,SH2D1A |
| 2.094e-02 | -3.87 | KCNJ12 (potassium inwardly rectifying channel subfamily J member 12) | protein interactions | 3768 | 27 | 13 | 19454 | 5460 |
CASK,PALS2,RHOG,KCNJ10,SNTA1,CAV3,DLG3,LIN7B,RHOJ,RAC2,LIN7C,DLG4,DLG1 |
| 2.094e-02 | -3.87 | THAP8 (THAP domain containing 8) | protein interactions | 199745 | 27 | 13 | 19454 | 5460 |
NMI,ALCAM,RAB14,LASP1,TMED9,DYNLL1,ATP5IF1,CYRIB,TFIP11,PSMG3,TOP3B,SNAP29,TP53 |
| 2.094e-02 | -3.87 | BICC1 (BicC family RNA binding protein 1) | protein interactions | 80114 | 27 | 13 | 19454 | 5460 |
NUP35,GABARAP,PRRC2A,VIRMA,TFG,SPPL3,CAPZA2,YWHAG,GABARAPL1,YWHAH,GABARAPL2,NEK7,CSK |
| 2.094e-02 | -3.87 | MTCL3 (MTCL family member 3) | protein interactions | 387104 | 27 | 13 | 19454 | 5460 |
RIOK2,PPP2R1A,EFHD1,SCN3B,SNRPN,PPP2R5A,EIF1AX,PRKCB,RTN4,PPP2R5E,SPECC1L,NRBF2,HS2ST1 |
| 2.094e-02 | -3.87 | PPEF2 (protein phosphatase with EF-hand domain 2) | protein interactions | 5470 | 27 | 13 | 19454 | 5460 |
NUDCD3,YWHAG,RPS7,PPARG,FKBP4,HAX1,AKAP8L,PIH1D1,RPAP3,KRT8,SPPL3,DNAAF10,CACYBP |
| 2.094e-02 | -3.87 | SDR39U1 (short chain dehydrogenase/reductase family 39U member 1) | protein interactions | 56948 | 27 | 13 | 19454 | 5460 |
CDC42,MRPL12,PPP1CC,RHOG,RHOB,FAHD1,HSPD1,AMACR,MALSU1,APEX1,RHOH,RHOJ,RASL10B |
| 2.094e-02 | -3.87 | CAPN10 (calpain 10) | protein interactions | 11132 | 27 | 13 | 19454 | 5460 |
TUBA1A,STK4,MAP1S,CCT2,EFNB1,ZMYM2,MAP1B,STK3,FLOT1,CCT7,AHCYL1,RIGI,TCP1 |
| 2.094e-02 | -3.87 | SYNGR3 (synaptogyrin 3) | protein interactions | 9143 | 27 | 13 | 19454 | 5460 |
ESR2,MPP1,ARFIP1,GAD2,SLC6A3,IRF3,SLC39A9,RUSF1,SH3GLB1,KLRC2,SPG21,TMEM59,EHHADH |
| 2.094e-02 | -3.87 | LTA (lymphotoxin alpha) | protein interactions | 4049 | 27 | 13 | 19454 | 5460 |
LTB,ACTB,TUBB,HSPA5,TMEM237,LTBR,LTA,TUBA1B,HDHD5,TNFRSF1B,TNFRSF14,CREB3,TUBA1A |
| 2.094e-02 | -3.87 | SH3BP5 (SH3 domain binding protein 5) | protein interactions | 9467 | 27 | 13 | 19454 | 5460 |
RAB11A,MOV10,SPTBN1,EXOC1,XPO1,MAPK10,RNF146,DISC1,ALB,TNKS,RAB11B,CDC5L,TNKS2 |
| 2.094e-02 | -3.87 | MAP3K8 (mitogen-activated protein kinase kinase kinase 8) | protein interactions | 1326 | 27 | 13 | 19454 | 5460 |
MAP2K1,BMPR2,TRAF6,CAMK2G,HSP90AA1,TAB2,NDUFA4,CD40,AKT1,NFKB1,MAP3K14,XPO1,TRAF2 |
| 2.096e-02 | -3.87 | WDR3 (WD repeat domain 3) | protein interactions | 10885 | 147 | 53 | 19454 | 5460 |
OXSR1,RPL26L1,RPA2,RPL27A,WDR77,COIL,EIF4E,STAU1,RPL4,EXOSC4,NUP50,RPA3,PNO1,SIRT7,DNAJB6,UBE2H,RIT1,ATG3,RC3H2,DNAJC8,MYC,ESR2,SNRNP40,PRMT5,PSPC1,CCNF,NUPR1,CBX3,HSPA13,CHMP4C,MAP1LC3B,SOX2,RAF1,TP53,G3BP1,KRAS,RPS24,RPL31,SNIP1,MPHOSPH6,CHCHD1,DDRGK1,GRSF1,IFI16,SURF6,RPL35A,RPS16,NOP58,CCAR2,EED,PWP2,CD274,FBXO32 |
| 2.103e-02 | -3.86 | RIF1 (replication timing regulatory factor 1) | protein interactions | 55183 | 201 | 70 | 19454 | 5460 |
BRCA1,UBE2H,THOC6,CUL3,GPR17,MYC,OST4,USP14,PPP1CC,PRDX2,MATR3,VIRMA,APEX1,APLNR,UBN1,CHRM4,SCN2B,IDH2,PPT1,RPA2,LMNA,CDAN1,CCND1,ALKBH3,CDK7,PPP1CB,STAU1,SLC15A1,NUCKS1,RNF41,SIRT7,RPA3,SLC39A9,HIRA,EP300,RNF113A,SMCHD1,BRD3,DDX1,ZDHHC15,FOXC2,HMGA1,LAMP3,P2RY10,SUMO2,MRPL50,TMED9,LRWD1,CDC5L,FEZ1,DEFB1,H2AZ1,ARL4D,SHLD1,EED,HDAC11,NECAP1,CBX3,CDK8,RAF1,MGARP,PPP2R1A,VRK1,VDAC1,ASF1A,H3C1,SSRP1,MDC1,TRIM21,HAPSTR1 |
| 2.104e-02 | -3.86 | CIAO1 (cytosolic iron-sulfur assembly component 1) | protein interactions | 9391 | 285 | 96 | 19454 | 5460 |
CIAO3,EIF3D,GAS8,MRPL9,HSPB8,ELP6,SKIC8,RPL9,TCP1,CCAR2,NOP58,CPLX3,CCT7,NUP35,EGLN3,SPC24,TOP3B,MAK16,CSTPP1,MOB3C,UCKL1,CCT8,MRPS11,PDIA6,ERP29,RTCB,KRAS,CCAR1,AP1M1,NOP16,MYC,RBM15B,MLF2,RPS29,CCT2,DNAJB6,YAE1,MTM1,IREB2,POLR2B,PAFAH1B1,PGRMC1,EHD1,ACAA2,CTBP1,UPF3B,CCDC9B,MIA2,NMRAL1,TXNL1,POLA2,PPIL4,LANCL2,SLC2A1,AIP,WDCP,SPPL3,ARL6IP5,TMPO,CDK9,ILVBL,DKC1,CCT5,PREB,CCDC47,COMTD1,RPAP2,TCOF1,ABCE1,MEPCE,CIAO1,NONO,HMOX2,UBE2H,CDC73,UQCRC2,CCNF,CTU1,PHAX,PPAT,RPL22,DUSP10,UBA52,RABL3,ELP3,CNP,KDELR2,HCST,HSP90B1,RSAD2,CDK1,JUP,UGDH,PRIM2,RTN4,RGS2 |
| 2.109e-02 | -3.86 | ZNF287 (zinc finger protein 287) | protein interactions | 57336 | 14 | 8 | 19454 | 5460 |
TRIM24,DVL2,IPO8,ZNF24,MEPCE,SPPL3,SCAND1,MPP1 |
| 2.109e-02 | -3.86 | AZIN2 (antizyme inhibitor 2) | protein interactions | 113451 | 14 | 8 | 19454 | 5460 |
TPD52L1,RB1CC1,OAZ1,LRIF1,SMG8,OAZ2,PSMC5,OAZ3 |
| 2.109e-02 | -3.86 | NLRP6 (NLR family pyrin domain containing 6) | protein interactions | 171389 | 14 | 8 | 19454 | 5460 |
ESR2,TAB2,PHB2,BECN1,SQSTM1,MAP1LC3A,PYCARD,ATG16L1 |
| 2.109e-02 | -3.86 | FBXL20 (F-box and leucine rich repeat protein 20) | protein interactions | 84961 | 14 | 8 | 19454 | 5460 |
RABGGTB,CCDC47,FBXO31,PDE6D,SKP1,BAX,UBE2D1,KRAS |
| 2.109e-02 | -3.86 | CYP1B1 (cytochrome P450 family 1 subfamily B member 1) | protein interactions | 1545 | 14 | 8 | 19454 | 5460 |
H3C1,ESR2,RIGI,PGRMC1,CNPY3,HSPB2,EP300,RAC2 |
| 2.109e-02 | -3.86 | CHAT (choline O-acetyltransferase) | protein interactions | 1103 | 14 | 8 | 19454 | 5460 |
ACAA2,PRKCE,CAMK2G,HSP90AA1,RARS1,PRKCA,STUB1,PRKCB |
| 2.109e-02 | -3.86 | TFEC (transcription factor EC) | protein interactions | 22797 | 14 | 8 | 19454 | 5460 |
HNRNPA1,DCK,LDLR,ZMAT2,TFEB,TFE3,SMCO4,MITF |
| 2.109e-02 | -3.86 | Cstf2t (cleavage stimulation factor, 3' pre-RNA subunit 2, tau) | protein interactions | 83410 | 14 | 8 | 19454 | 5460 |
CTBP1,CCAR2,RBM7,RPL18,TXNL4A,PPIL3,PRKRA,ESS2 |
| 2.109e-02 | -3.86 | Gtf3c2 (general transcription factor IIIC, polypeptide 2, beta) | protein interactions | 71752 | 14 | 8 | 19454 | 5460 |
ADNP,TAF10,GTF3C3,RPL28,ZMYM2,ZMAT3,SLC39A10,GTF3C4 |
| 2.109e-02 | -3.86 | C2CD4C (C2 calcium dependent domain containing 4C) | protein interactions | 126567 | 14 | 8 | 19454 | 5460 |
CDC42,DIRAS3,CAV1,PTEN,KRAS,ARF6,LAMP2,RHOB |
| 2.109e-02 | -3.86 | IL10RB (interleukin 10 receptor subunit beta) | protein interactions | 3588 | 14 | 8 | 19454 | 5460 |
IL10,ATG16L1,E2F4,IL22,SRC,RIGI,CTLA4,PIK3CA |
| 2.109e-02 | -3.86 | NOX5 (NADPH oxidase 5) | protein interactions | 79400 | 14 | 8 | 19454 | 5460 |
TTC4,PDP2,HSP90AA1,GUCY1B1,STUB1,UBE2I,DDRGK1,HSPA8 |
| 2.109e-02 | -3.86 | PGPEP1 (pyroglutamyl-peptidase I) | protein interactions | 54858 | 14 | 8 | 19454 | 5460 |
RIGI,SELENOO,GTF2I,HBB,UBE2E3,NTAQ1,TRIM11,UBE2E2 |
| 2.109e-02 | -3.86 | COL5A2 (collagen type V alpha 2 chain) | protein interactions | 1290 | 14 | 8 | 19454 | 5460 |
CHMP4C,PRNP,BMP1,FBXO22,MOB3C,RAF1,DDR1,EWSR1 |
| 2.109e-02 | -3.86 | CCDC7 (coiled-coil domain containing 7) | protein interactions | 79741 | 14 | 8 | 19454 | 5460 |
ZDHHC17,RAD21,VIRMA,CSK,ITGA6,CIAO1,EWSR1,PTEN |
| 2.109e-02 | -3.86 | NLRP5 (NLR family pyrin domain containing 5) | protein interactions | 126206 | 14 | 8 | 19454 | 5460 |
TXNDC17,LRRC1,BAG2,MATR3,BECN1,MEPCE,NLRP3,NLRP2 |
| 2.109e-02 | -3.86 | RGS6 (regulator of G protein signaling 6) | protein interactions | 9628 | 14 | 8 | 19454 | 5460 |
GNB1,CCDC85B,GNB4,HSP90AA1,DMAP1,STMN2,GNB3,HMGA1 |
| 2.109e-02 | -3.86 | GRK1 (G protein-coupled receptor kinase 1) | protein interactions | 6011 | 14 | 8 | 19454 | 5460 |
MYC,SNCG,SNCB,RCVRN,ADRB2,H2AZ2,CAV1,PDE6D |
| 2.109e-02 | -3.86 | DACH2 (dachshund family transcription factor 2) | protein interactions | 117154 | 14 | 8 | 19454 | 5460 |
TRIM26,SPPL3,ATP6V1G1,TRIM44,IRF9,CFTR,DDX39A,CD2AP |
| 2.109e-02 | -3.86 | RNF121 (ring finger protein 121) | protein interactions | 55298 | 14 | 8 | 19454 | 5460 |
PDE2A,LPAR1,FBXO7,BSCL2,ARL10,NFKBIA,EDEM1,CSK |
| 2.109e-02 | -3.86 | TLNRD1 (talin rod domain containing 1) | protein interactions | 59274 | 14 | 8 | 19454 | 5460 |
CCM2,KRIT1,TLNRD1,LRP6,TOP3B,PLA2G5,PICK1,LDLR |
| 2.109e-02 | -3.86 | FFAR3 (free fatty acid receptor 3) | protein interactions | 2865 | 14 | 8 | 19454 | 5460 |
SERINC1,SLC41A1,CTXN3,TEX264,COMT,TOMM6,EFNA5,KRAS |
| 2.109e-02 | -3.86 | BNIPL (BCL2 interacting protein like) | protein interactions | 149428 | 14 | 8 | 19454 | 5460 |
SNAPIN,RHOU,PYCR1,ARHGAP1,BCL2L1,FKBP8,NME2,MIF |
| 2.109e-02 | -3.86 | HERC6 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 6) | protein interactions | 55008 | 14 | 8 | 19454 | 5460 |
HERC4,UBE2L3,HSP90AA1,NME2,KCTD15,TP53,HERC3,CSK |
| 2.109e-02 | -3.86 | GUCY1A2 (guanylate cyclase 1 soluble subunit alpha 2) | protein interactions | 2977 | 14 | 8 | 19454 | 5460 |
HSP90AA1,SNTA1,DDX39A,GUCY1B1,DLG1,DLG3,DLG4,STUB1 |
| 2.109e-02 | -3.86 | PLA2G12A (phospholipase A2 group XIIA) | protein interactions | 81579 | 14 | 8 | 19454 | 5460 |
MEF2C,RPS15,DVL2,UMPS,UCK1,YWHAG,RB1,HSPA5 |
| 2.110e-02 | -3.86 | regulation of receptor signaling pathway via STAT | biological process | GO:1904892 | 93 | 37 | 18204 | 5365 |
MIR146A,LEP,ADIPOR1,MIR99A,MIR149,MIRLET7C,PPARG,MIR221,F2,GHR,KIT,IL4,OCIAD2,CYP1B1,MIR340,PRL,CSH1,CLEC12B,NF2,IFNAR1,MIR874,MIR9-1,SOCS2,GH1,IL6,VEGFA,HGS,MIR125A,IL10,IL5,EP300,JAK2,SOCS3,CRLF3,CCL5,TNF,CAV1 |
| 2.112e-02 | -3.86 | Formation of HIV-1 elongation complex containing HIV-1 Tat | REACTOME pathways | R-HSA-167200 | 50 | 23 | 10285 | 3229 |
NCBP2,POLR2B,SSRP1,SUPT5H,ERCC3,MNAT1,CDK7,CDK9,TCEA1,GTF2H5,POLR2L,POLR2I,POLR2D,GTF2H2,GTF2F1,GTF2F2,GTF2H4,SUPT4H1,CCNH,POLR2G,ELOC,POLR2C,POLR2F |
| 2.112e-02 | -3.86 | Tat-mediated elongation of the HIV-1 transcript | REACTOME pathways | R-HSA-167246 | 50 | 23 | 10285 | 3229 |
GTF2H4,CCNH,POLR2C,POLR2I,GTF2F1,CDK9,SSRP1,ERCC3,GTF2F2,ELOC,POLR2G,SUPT4H1,POLR2F,TCEA1,POLR2D,GTF2H5,POLR2L,GTF2H2,CDK7,POLR2B,NCBP2,SUPT5H,MNAT1 |
| 2.112e-02 | -3.86 | HIV Transcription Elongation | REACTOME pathways | R-HSA-167169 | 50 | 23 | 10285 | 3229 |
CDK9,CDK7,MNAT1,SSRP1,POLR2B,NCBP2,ERCC3,SUPT5H,POLR2F,GTF2H4,GTF2F2,CCNH,ELOC,POLR2C,POLR2G,SUPT4H1,POLR2D,GTF2H5,POLR2L,POLR2I,GTF2F1,GTF2H2,TCEA1 |
| 2.118e-02 | -3.85 | human chr12q23.3 | chromosome location | human chr12q23.3 | 47 | 17 | 26134 | 5823 |
GLT8D2,TXNRD1,TCP11L2,HCFC2,NFYB,SART3,PRDM4,MTERF2,POLR3B,RFX4,ISCU,HSP90B1,CHST11,NOPCHAP1,UQCC6,CRY1,TMEM263 |
| 2.120e-02 | -3.85 | ACTA1 (actin alpha 1, skeletal muscle) | protein interactions | 58 | 321 | 107 | 19454 | 5460 |
SPTAN1,FOLR1,DNM2,PPM1B,CBL,POU5F1,COTL1,PIK3R1,MTRF1,KIT,LASP1,TRIM37,PFDN1,PSMD12,HNRNPDL,MAEA,SLC39A3,ACTR1B,UBE3A,SMARCB1,MOB3C,ERRFI1,ACTN4,ISG15,NCSTN,MAK16,LGALS3,NCKAP1,USP5,CCT2,MYO6,RHOB,HTRA2,SERPINH1,POLR1B,MYC,EPS8,SFN,RRN3,BTF3,NMRAL1,EP300,ADSS2,UBAC2,PIH1D1,CSNK1A1,USP6NL,SLC16A10,PPP1CB,ETV6,HCLS1,ACTA2,DSTN,TES,CEBPG,SHC1,PCYT1B,TPM3,CCIN,CHMP1B,CTNNBL1,TRIM63,CTNND1,MEPCE,DUSP19,RNF167,DLG1,DHX9,PPP1R1A,TNNI1,DMAP1,TFCP2,CAPZA2,ACTR2,TNNI3K,CCDC69,UBL4A,CCT5,TP53,TRIM6,PRKCE,SRC,CTTN,TMSB4X,GAS2,GANAB,CYTH1,RC3H2,XPOT,CAP2,AKT1,IL2RB,MORF4L1,CFL1,ELOVL3,MRPL40,AIF1,HSPA5,PHACTR1,PRKCB,HSPB2,ITGA2,FGFR1,PTPN22,PRKCA,HEXIM1,CDK7 |
| 2.120e-02 | -3.85 | oligopeptide binding | molecular function | GO:1900750 | 11 | 7 | 18094 | 5411 |
GSTM3,LANCL1,PTGES,MGST2,MMACHC,GSTM4,GSTM2 |
| 2.120e-02 | -3.85 | enoyl-CoA hydratase activity | molecular function | GO:0004300 | 11 | 7 | 18094 | 5411 |
HACD4,HADHA,HACD2,AUH,EHHADH,HACD3,HACD1 |
| 2.120e-02 | -3.85 | ADP transmembrane transporter activity | molecular function | GO:0015217 | 11 | 7 | 18094 | 5411 |
SLC25A5,SLC25A24,SLC25A4,SLC25A23,SLC25A17,SLC25A31,SLC25A42 |
| 2.120e-02 | -3.85 | transferrin receptor binding | molecular function | GO:1990459 | 11 | 7 | 18094 | 5411 |
IKBKB,CD81,SNX1,SNX2,TF,HFE,RGMA |
| 2.120e-02 | -3.85 | nitric-oxide synthase binding | molecular function | GO:0050998 | 11 | 7 | 18094 | 5411 |
NOS1AP,ATP2B4,SLC6A4,CAV1,ACTB,CAV3,SNTA1 |
| 2.120e-02 | -3.85 | phosphatidylinositol 3-kinase regulatory subunit binding | molecular function | GO:0036312 | 11 | 7 | 18094 | 5411 |
FAM83A,PIK3R1,PIK3AP1,CBL,PIK3R2,FAM83B,CD2AP |
| 2.124e-02 | -3.85 | Abhydrolase_1 | pfam domains | PF00561 | 26 | 13 | 17795 | 5224 |
MEST,ABHD16B,SPG21,ABHD2,ABHD13,ABHD10,ABHD6,EPHX1,ABHD12,ABHD8,ABHD5,LIPA,ABHD4 |
| 2.131e-02 | -3.85 | IL6-mediated signaling events | Pathway Interaction DB | il6_7pathway | 43 | 22 | 2226 | 782 |
PIK3CA,IL6,STAT1,IL6ST,LMO4,PTPN11,JAK2,JUN,MITF,HSP90B1,IRF1,JUNB,MCL1,MAP2K6,FOS,TIMP1,JAK1,PIK3R1,MYC,SOCS3,PIAS1,AKT1 |
| 2.134e-02 | -3.85 | FLOT1 (flotillin 1) | protein interactions | 10211 | 453 | 147 | 19454 | 5460 |
IRF3,RPA3,RHOU,PIK3R2,CERS2,NF2,YKT6,RPS15,UBA52,PDE8A,SPTBN1,CFTR,FTH1,GABRA1,CDC42,WWP1,PICALM,SLC12A2,RPA2,JUP,CSNK1G3,NECTIN2,CTNNA1,GAB1,ACAT1,SEC61A1,RHOJ,YES1,SLC25A4,STAT5A,ROCK1,FERMT2,RAB2A,RSPH1,GORASP2,AR,ATP5F1A,ARHGAP21,FBXO7,DNAJC19,SMAD2,EPHA2,IGF2BP1,SLC25A11,DLG1,PALM2AKAP2,SLC25A10,SNAP23,RING1,SEPTIN7,ABCE1,AKAP12,H3C1,ADD2,RIGI,SLC6A8,CTNND1,APOO,DISC1,CAPZA2,EXOC3,TFCP2,TFRC,NUPR1,SLC25A24,CASK,EHBP1,PTPN1,HRAS,ETV6,RAC2,CDCA3,ADD1,SLC39A10,PRNP,CGAS,MRPL50,CAV1,ILVBL,SLC38A2,LAMTOR2,HM13,HDAC6,TIAM1,NOS1AP,PCGF2,DNAL4,EMC1,NOTCH2,USP6NL,RND2,FAM3C,ELF5,CCDC90B,DLST,GNG12,FAM83B,PSMD4,ESR2,ATP6AP2,APEX1,POLR2B,RAB11A,LDHB,PKP4,NIBAN2,IRF1,RHOB,LAMTOR1,SLC38A1,MAEA,MYO1B,EFNB1,RUVBL1,S100A10,KRAS,RANBP1,RAF1,ERLIN2,SOX2,ISG15,PTRH2,NGB,NDUFS6,PDHA1,EZH2,IRF8,VAMP2,HGS,MYEF2,RAB31,WDR6,EED,SPTAN1,RHOH,MARCHF5,RAB5C,SYNJ2BP,UBXN6,PIK3R1,CTNNB1,PPFIBP1,RHOG,BCL2L1,CBL,HAX1,RASSF8 |
| 2.137e-02 | -3.85 | CD40 (CD40 molecule) | protein interactions | 958 | 144 | 52 | 19454 | 5460 |
TANK,TTI2,BIRC2,HSPA8,XRCC5,CD40,NCDN,CMTM6,TLCD1,SLC7A1,BAG3,TRAF3IP2,RFC5,EXOC5,HTRA2,GEMIN8,SLC30A7,PLP1,TRAF1,TNPO3,REEP4,CD40LG,TXN,TNPO2,TRAF2,INSIG2,IPO8,ARFGEF1,NHERF1,PIK3CA,TMEM147,SLC39A7,FAF1,CSE1L,FAM241A,HDAC6,TMEM107,PIK3R1,CALR,USP15,CBL,SLC39A13,TRAF6,IKBKB,MFSD5,XPO5,DEFB121,CAV1,EIF2B5,EIF2B2,ATXN10,COG1 |
| 2.139e-02 | -3.85 | cellular response to monosaccharide stimulus | biological process | GO:0071326 | 96 | 38 | 18204 | 5365 |
MIR320A,PPP3CA,PLCB1,PCK2,GCLC,KCNJ11,XBP1,RAB11B,SMAD2,CCDC186,SLC29A1,CYP7A1,OPRK1,MIR146A,LEP,SMAD4,NPTX1,SELENOT,AGER,PPARA,PIK3CA,PAX6,SIN3A,KCNB1,UCP2,SMAD3,ICAM1,RAF1,MIR16-1,CMA1,TRA2B,MIRLET7G,IGF1R,TWNK,FKBP1B,GPX1,MIR15A,CLTRN |
| 2.148e-02 | -3.84 | DFDF | prosite domains | PS51512 | 3 | 3 | 12186 | 3388 |
EDC3,LSM14A,LSM14B |
| 2.148e-02 | -3.84 | RIBOSOMAL_L24 | prosite domains | PS01108 | 3 | 3 | 12186 | 3388 |
RPL26L1,MRPL24,RPL26 |
| 2.148e-02 | -3.84 | MYELIN_PLP_2 | prosite domains | PS01004 | 3 | 3 | 12186 | 3388 |
GPM6A,GPM6B,PLP1 |
| 2.148e-02 | -3.84 | HSP90 | prosite domains | PS00298 | 3 | 3 | 12186 | 3388 |
HSP90AA1,HSP90B1,HSP90AB1 |
| 2.148e-02 | -3.84 | SOD_CU_ZN_2 | prosite domains | PS00332 | 3 | 3 | 12186 | 3388 |
SOD3,CCS,SOD1 |
| 2.148e-02 | -3.84 | ODC_AZ | prosite domains | PS01337 | 3 | 3 | 12186 | 3388 |
OAZ1,OAZ2,OAZ3 |
| 2.148e-02 | -3.84 | SAM_OMT_I | prosite domains | PS51682 | 3 | 3 | 12186 | 3388 |
COMTD1,LRTOMT,COMT |
| 2.148e-02 | -3.84 | T4_DEIODINASE | prosite domains | PS01205 | 3 | 3 | 12186 | 3388 |
DIO2,DIO1,DIO3 |
| 2.148e-02 | -3.84 | ODR_DC_2_2 | prosite domains | PS00879 | 3 | 3 | 12186 | 3388 |
AZIN1,ODC1,AZIN2 |
| 2.148e-02 | -3.84 | MYELIN_PLP_1 | prosite domains | PS00575 | 3 | 3 | 12186 | 3388 |
GPM6A,GPM6B,PLP1 |
| 2.148e-02 | -3.84 | RNA_POL_BETA | prosite domains | PS01166 | 3 | 3 | 12186 | 3388 |
POLR2B,POLR1B,POLR3B |
| 2.148e-02 | -3.84 | ACONITASE_2 | prosite domains | PS01244 | 3 | 3 | 12186 | 3388 |
IREB2,ACO2,ACO1 |
| 2.148e-02 | -3.84 | ACONITASE_1 | prosite domains | PS00450 | 3 | 3 | 12186 | 3388 |
ACO1,ACO2,IREB2 |
| 2.148e-02 | -3.84 | CAVEOLIN | prosite domains | PS01210 | 3 | 3 | 12186 | 3388 |
CAV2,CAV3,CAV1 |
| 2.149e-02 | -3.84 | production of molecular mediator of immune response | biological process | GO:0002440 | 53 | 23 | 18204 | 5365 |
EXOSC3,SAMHD1,SHLD1,TRAF3IP2,SWAP70,GAPT,POLB,HMCES,MAD2L2,SLAMF9,CD40LG,NBN,BATF,NHEJ1,MSH6,STAT6,RNF8,CCR6,POLL,CTNNBL1,FOXP3,BCL6,HSPD1 |
| 2.149e-02 | -3.84 | regulation of cardiac muscle cell apoptotic process | biological process | GO:0010665 | 53 | 23 | 18204 | 5365 |
MIR34A,NUPR1,MIR195,MIR16-1,MIR145,BMPR1A,MIR24-1,TP53,MIR106B,JAK2,NFE2L2,MIR21,HAND2,PPP1R10,SMAD4,RGL2,HEY2,CAPN2,MIR30E,HSPA8,MIR20A,MIR320A,MIR17 |
| 2.149e-02 | -3.84 | endoplasmic reticulum unfolded protein response | biological process | GO:0030968 | 53 | 23 | 18204 | 5365 |
HSPA5,DNAJC10,VAPB,STUB1,NFE2L2,XBP1,CREBZF,OS9,ERO1A,DERL2,RPAP2,PTPN1,EIF2AK2,CCND1,EIF2S1,ATF3,CDK5RAP3,SELENOS,DDIT3,ERLEC1,ATF4,DERL1,CREB3 |
| 2.150e-02 | -3.84 | PLEKHS1 (pleckstrin homology domain containing S1) | protein interactions | 79949 | 7 | 5 | 19454 | 5460 |
PIK3R3,PBLD,EZH2,TCP11L1,PDCD10 |
| 2.150e-02 | -3.84 | RPL10P16 (ribosomal protein L10 pseudogene 16) | protein interactions | 284393 | 7 | 5 | 19454 | 5460 |
CUL2,CUL3,NEDD8,CAND1,COPS5 |
| 2.150e-02 | -3.84 | SLC16A5 (solute carrier family 16 member 5) | protein interactions | 9121 | 7 | 5 | 19454 | 5460 |
TOP3B,PTPRZ1,HSPB8,BCL2L1,MGAT5B |
| 2.150e-02 | -3.84 | PRRT1 (proline rich transmembrane protein 1) | protein interactions | 80863 | 7 | 5 | 19454 | 5460 |
FAM241B,ARL6IP5,TRIM63,PRRT1,REEP6 |
| 2.150e-02 | -3.84 | C10orf71 (chromosome 10 open reading frame 71) | protein interactions | 118461 | 7 | 5 | 19454 | 5460 |
DYRK1B,FNTB,DYRK1A,TRIM24,FGF1 |
| 2.150e-02 | -3.84 | RPSAP55 (ribosomal protein SA pseudogene 55) | protein interactions | 388122 | 7 | 5 | 19454 | 5460 |
COPS5,CAND1,NEDD8,CUL2,CUL3 |
| 2.150e-02 | -3.84 | PMP2 (peripheral myelin protein 2) | protein interactions | 5375 | 7 | 5 | 19454 | 5460 |
AKR1B1,HINT1,SOD1,TAGLN2,ENO1 |
| 2.150e-02 | -3.84 | NTNG2 (netrin G2) | protein interactions | 84628 | 7 | 5 | 19454 | 5460 |
EWSR1,CCR2,ADRA1A,LRRC4,TRIM37 |
| 2.150e-02 | -3.84 | SBNO2 (strawberry notch homolog 2) | protein interactions | 22904 | 7 | 5 | 19454 | 5460 |
RIGI,TOP3B,HNRNPL,TCEAL1,PML |
| 2.150e-02 | -3.84 | CDCA7 (cell division cycle associated 7) | protein interactions | 83879 | 7 | 5 | 19454 | 5460 |
SFN,YWHAZ,APEX1,YWHAH,YWHAG |
| 2.150e-02 | -3.84 | Uhmk1 (U2AF homology motif (UHM) kinase 1) | protein interactions | 16589 | 7 | 5 | 19454 | 5460 |
SMAD4,BMPR1B,ACVR1,SMURF1,SMAD2 |
| 2.150e-02 | -3.84 | BAG6 (BAG cochaperone 6) | protein interactions | 100350337 | 7 | 5 | 19454 | 5460 |
VAMP2,SYNJ2BP,ATP5MC1,SEC61B,SGTA |
| 2.150e-02 | -3.84 | DENND1C (DENN domain containing 1C) | protein interactions | 79958 | 7 | 5 | 19454 | 5460 |
DAPK1,RIGI,EIF4B,HSPA8,SNAPIN |
| 2.150e-02 | -3.84 | Tbk1 (TANK-binding kinase 1) | protein interactions | 56480 | 7 | 5 | 19454 | 5460 |
TANK,C9orf72,OPTN,CCNF,IRF1 |
| 2.150e-02 | -3.84 | KCNK15 (potassium two pore domain channel subfamily K member 15) | protein interactions | 60598 | 7 | 5 | 19454 | 5460 |
YWHAZ,SFN,YWHAB,YWHAG,YWHAH |
| 2.150e-02 | -3.84 | RGS18 (regulator of G protein signaling 18) | protein interactions | 64407 | 7 | 5 | 19454 | 5460 |
GNAQ,GNAI2,GNAI3,LMNA,SPPL3 |
| 2.150e-02 | -3.84 | LRAT (lecithin retinol acyltransferase) | protein interactions | 9227 | 7 | 5 | 19454 | 5460 |
TMX2,RBP2,TMEM31,BLCAP,LRAT |
| 2.150e-02 | -3.84 | SOAT2 (sterol O-acyltransferase 2) | protein interactions | 8435 | 7 | 5 | 19454 | 5460 |
E2F4,CSK,CLU,TMBIM6,BAG3 |
| 2.150e-02 | -3.84 | CCDC80 (coiled-coil domain containing 80) | protein interactions | 151887 | 7 | 5 | 19454 | 5460 |
CFTR,VIRMA,MYC,ESYT1,DLST |
| 2.150e-02 | -3.84 | LRTM1 (leucine rich repeats and transmembrane domains 1) | protein interactions | 57408 | 7 | 5 | 19454 | 5460 |
PITHD1,GNPDA2,ATPAF2,NAE1,UBA3 |
| 2.150e-02 | -3.84 | CGB5 (chorionic gonadotropin subunit beta 5) | protein interactions | 93659 | 7 | 5 | 19454 | 5460 |
KRAS,SMCP,CFTR,DNAJC5,RIT1 |
| 2.150e-02 | -3.84 | Fbxo3 (F-box protein 3) | protein interactions | 57443 | 7 | 5 | 19454 | 5460 |
ACVR1,SMAD3,BMPR1B,SMAD2,SMURF1 |
| 2.150e-02 | -3.84 | CFAP47 (cilia and flagella associated protein 47) | protein interactions | 286464 | 7 | 5 | 19454 | 5460 |
CFTR,SRP54,UBB,RPL35,BRCA1 |
| 2.150e-02 | -3.84 | TMEM116 (transmembrane protein 116) | protein interactions | 89894 | 7 | 5 | 19454 | 5460 |
LCN1,NRP1,TP53,CSK,RETSAT |
| 2.150e-02 | -3.84 | BCAS1 (brain enriched myelin associated protein 1) | protein interactions | 8537 | 7 | 5 | 19454 | 5460 |
ESR2,CFTR,RUVBL2,DYNLL1,PRNP |
| 2.150e-02 | -3.84 | SOX18 (SRY-box transcription factor 18) | protein interactions | 54345 | 7 | 5 | 19454 | 5460 |
STK11,GKAP1,MECP2,MEF2C,HMGB1 |
| 2.150e-02 | -3.84 | NIPA1 (NIPA magnesium transporter 1) | protein interactions | 123606 | 7 | 5 | 19454 | 5460 |
SELENOM,RIGI,CCDC167,TOM1L1,CCDC47 |
| 2.150e-02 | -3.84 | SYCN (syncollin) | protein interactions | 342898 | 7 | 5 | 19454 | 5460 |
CNTNAP1,AIP,HSPA5,BIRC2,H2BC9 |
| 2.152e-02 | -3.84 | APC/C complex | KEGG pathways | hsa_M00389 | 14 | 9 | 7161 | 2463 |
FZR1,ANAPC4,CDC26,ANAPC13,CDC23,CDC16,ANAPC2,ANAPC11,CDC20 |
| 2.152e-02 | -3.84 | APC/C complex | KEGG pathways | M00389 | 14 | 9 | 7161 | 2463 |
ANAPC13,CDC26,ANAPC4,FZR1,CDC20,ANAPC11,ANAPC2,CDC16,CDC23 |
| 2.152e-02 | -3.84 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | ko00533 | 14 | 9 | 7161 | 2463 |
B3GNT2,CHST1,FUT8,B4GALT3,B4GALT1,B4GALT4,ST3GAL1,ST3GAL2,CHST2 |
| 2.152e-02 | -3.84 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | hsa00533 | 14 | 9 | 7161 | 2463 |
B4GALT1,B4GALT3,B4GALT4,CHST2,ST3GAL2,ST3GAL1,CHST1,B3GNT2,FUT8 |
| 2.153e-02 | -3.84 | regulation of hydrolase activity | biological process | GO:0051336 | 726 | 239 | 18204 | 5365 |
NCSTN,RGS6,VEGFA,PSMB9,RALGAPA2,EZH2,ITK,TIMP1,LGALS3,SERPINA3,AGAP1,APOC2,GAPDH,PRELID1,IKBKB,NTRK2,PPARG,NTRK3,CXCL13,IFI16,PSME2,RGP1,CCL1,RHOG,GPIHBP1,CLEC7A,ROCK1,ITGA6,SERPINB11,MIR15A,TIAM1,TNFSF10,LPAR1,RGS1,IFNG,SVBP,CCL8,MIR590,PLCB2,KLF4,CCL11,PHB2,IFI6,FASLG,CD200,THY1,TIMP4,PSENEN,FAM162A,FGFR1,SERPINI1,SERPINH1,SRC,SH3BP4,ADRA1A,CHN2,PIH1D1,CRADD,CCL18,NLRP2,CCL4L1,DAP,TBC1D10C,TBC1D13,SEMG2,CCL2,HSP90B1,CCL19,CLDN3,CTSD,TBC1D16,MIR17,TBC1D17,TBC1D5,PSME1,CCL25,NLRP3,SERPINB1,RAP1A,AVPR1B,BIRC2,PHB1,RPS3,PPP1R1B,EGLN3,LAMP3,TNF,TBC1D1,ZC3H15,VSIR,DDRGK1,XCL1,MUL1,ROCK2,MIR24-1,CX3CL1,RAF1,SMAD3,S100A10,S100A8,NKX3-1,ARHGAP12,AGER,PYCARD,HRAS,NLRP1,DFFA,MIR205,SYK,CORO1C,HMGB1,MAPRE2,TMBIM6,CCL23,ARFGEF1,RGS2,CD40,EPHA2,CLDN4,AGAP2,HSP90AB1,CDKN2D,FKBP1B,PMAIP1,LPAR2,EFNA5,MEF2C,CAV1,GPR65,FURIN,VAV2,SERPINB9,BCL2A1,SIPA1L1,SFN,DNAJB6,ARL6IP5,PPP1R2,RPS27L,MIR21,RGS10,HTRA2,MCL1,SERPINB6,SERPINB10,IFT57,SERPINA1,SFRP1,CCL17,TIMP3,MYC,FERMT2,BAX,DAPK1,MMP9,CD86,GNAQ,CCL5,ACVR1C,EFNA3,CST3,TBC1D25,MMUT,EPHA4,BVES,SERPINA5,RNF34,CCL3,PLXNC1,PPP1R17,PDCD5,PPP1R12A,USP6NL,HSPD1,HTR2A,BCL10,PSMA3,CDK5RAP3,OAS1,ABCE1,BAD,FGD2,JAK2,FKBP1A,MIR29C,BCL2L1,PIP5K1A,RASGRP2,CAV2,PLA2G5,NR1H2,MIR339,ATP5IF1,FIS1,PAK2,CSTB,PLAA,MIRLET7B,CSTA,CAAP1,IGBP1,HSPE1,SOD1,CCL21,ODAM,CSNK2A1,MET,ARHGAP25,KIT,ANP32B,S1PR4,FAS,BAK1,PCNA,CTSK,CYFIP2,GPX1,CCL24,APH1A,DPEP1,TAX1BP3,BOK,CHP1,SNX18,MIR152,ARHGAP15,TANK,CCL20,KHDC1,C9orf72,SOX2,PKP4,SIAH2,TBC1D4,AKT1,SERPIND1,AIFM1,SPOCK1,TNFSF15 |
| 2.153e-02 | -3.84 | POGZ (pogo transposable element derived with ZNF domain) | protein interactions | 23126 | 256 | 87 | 19454 | 5460 |
COIL,PSMC1,EID2B,FTL,SLC31A1,LITAF,KDM1A,STAU1,FBXW7,NUCKS1,HSPB2,MIS12,RPA3,ACTMAP,SIRT7,FAM168B,NICN1,RPA2,KLF3,VAV2,PICALM,ADNP,KRTAP8-1,ZNF428,LRIF1,CBX5,MAD2L2,ESR2,APEX1,DYNLL1,SNRNP40,CSNK2B,ZMYM2,MACROH2A1,UFSP1,CREB1,TNFRSF1B,ENO1,ELK3,SP1,DSN1,RSPH1,HNF1B,MYC,NFYA,MDC1,PAX6,RIGI,PCGF6,H3C1,ASF1A,MYO1B,SNIP1,GLUL,KLHL26,HGS,CBX3,CHAMP1,GABPB1,SOX2,EGR2,H2AX,ELF1,ZMYM4,RAF1,ODAM,SP4,ZBTB2,ZNF576,TOP1,SUMO2,EED,CD4,CDK6,H2AZ1,COX4I1,BOLL,TNNC2,BRD3,LHX2,H2AC4,AGR2,XPO1,ANKRD10,MOV10,HMGA1,PFDN5 |
| 2.155e-02 | -3.84 | flotillin complex | cellular component | GO:0016600 | 9 | 6 | 19108 | 5553 |
SLC6A3,CBL,CTNNA1,CORO1C,FLOT1,CTNNB1 |
| 2.155e-02 | -3.84 | SMAD protein complex | cellular component | GO:0071141 | 9 | 6 | 19108 | 5553 |
SMAD4,SMAD3,SMAD2,SMAD1,SMAD5,SMAD9 |
| 2.158e-02 | -3.84 | GABPB1 (GA binding protein transcription factor subunit beta 1) | protein interactions | 2553 | 41 | 18 | 19454 | 5460 |
DHX16,KRAS,GABPA,TRIM63,ZDHHC17,FANCG,ESR2,SNRPB2,RIGI,SNRPA,EP300,YAF2,TDRD7,GSTP1,TRAF2,LMO4,ATF1,LMO3 |
| 2.158e-02 | -3.84 | ATP7B (ATPase copper transporting beta) | protein interactions | 540 | 41 | 18 | 19454 | 5460 |
RAB4A,DCTN4,LAMTOR1,NTRK3,DNAJB2,LAMP2,ATG9A,HP,LAMP3,GRPR,MANSC1,ZBTB16,CX3CL1,VIRMA,CLU,ITM2A,GLRX,RAB9A |
| 2.158e-02 | -3.84 | TMEM19 (transmembrane protein 19) | protein interactions | 55266 | 41 | 18 | 19454 | 5460 |
SERTM1,TLCD4,LEPROTL1,SUSD6,REEP4,GJB1,SPPL3,SLC7A1,PTGES,CD3G,BSCL2,ELOVL4,TMEM14B,MFSD14B,FCER1G,TMEM45A,DDX39A,CREB3 |
| 2.158e-02 | -3.84 | C11orf54 (chromosome 11 open reading frame 54) | protein interactions | 28970 | 41 | 18 | 19454 | 5460 |
CSK,SSX2IP,VAC14,ANXA7,AKR1A1,GSTO1,CCT2,PIR,GNPDA2,PRDX6,CCNF,SOD1,PEBP1,FKBP2,YKT6,AKR1C2,HNRNPL,NSFL1C |
| 2.158e-02 | -3.84 | ARHGEF26 (Rho guanine nucleotide exchange factor 26) | protein interactions | 26084 | 41 | 18 | 19454 | 5460 |
LIN7C,DLG1,VIRMA,MRPS7,DEK,HNRNPL,KRAS,RUVBL1,CPT2,PPIB,MMUT,CDC42,LIN7B,TP53,DLG3,CASK,RHOB,FGFR1 |
| 2.158e-02 | -3.84 | HEMGN (hemogen) | protein interactions | 55363 | 41 | 18 | 19454 | 5460 |
HMGA1,CTBP1,BCL10,SMAD4,EP300,TLR2,FLCN,HSPA8,ENO1,H2AC6,HMG20A,SRC,COPS4,MED17,FBXW7,KRAS,ODC1,MLH3 |
| 2.158e-02 | -3.84 | ZNF646 (zinc finger protein 646) | protein interactions | 9726 | 41 | 18 | 19454 | 5460 |
CBX3,NSA2,MDFI,NOTCH2,CUL3,ZNF668,TRAF2,GAPDH,SPPL3,RPS10,DGCR8,PRNP,SRSF4,VIRMA,RPL19,KRR1,PRKRA,UBE2I |
| 2.158e-02 | -3.84 | SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3) | protein interactions | 9901 | 41 | 18 | 19454 | 5460 |
ENKD1,VIRMA,KDM1A,S100A10,TNIK,VAMP3,PGGT1B,ZMPSTE24,LEMD3,VAMP2,DISC1,CCDC22,YWHAZ,SMCHD1,SUV39H1,DDRGK1,FASLG,PRMT6 |
| 2.158e-02 | -3.84 | KCNK16 (potassium two pore domain channel subfamily K member 16) | protein interactions | 83795 | 41 | 18 | 19454 | 5460 |
UBAC2,C1GALT1C1,EMC10,RETSAT,PREB,UFD1,RPL26,SEC62,DNAJB9,SPPL3,EMC8,RNF5,TMUB1,CCT7,GPAA1,TMX2,GJA1,RMDN3 |
| 2.158e-02 | -3.84 | SUMO1P1 (SUMO1 pseudogene 1) | protein interactions | 391257 | 41 | 18 | 19454 | 5460 |
CKS1B,HNRNPC,SUMO1,TRAF2,FAM200A,TRIM23,ZBTB26,NAB2,STX1A,STYK1,PHC1,PTRHD1,ZBTB6,UBE2I,SATB1,MAPK1IP1L,PIAS1,FAM118B |
| 2.161e-02 | -3.83 | glial cell projection | cellular component | GO:0097386 | 37 | 17 | 19108 | 5553 |
SYT4,SLC4A8,AIF1,GRM2,GJB2,WASF3,MT3,SLC1A2,TMEM50A,AQP4,GLUL,ADGRG1,LCP1,SLC7A11,EIF2S1,SLC1A1,KCNJ10 |
| 2.164e-02 | -3.83 | human chr14q12 | chromosome location | human chr14q12 | 65 | 22 | 26134 | 5823 |
MIR624,NOP9,CIDEB,PSME1,DTD2,IRF9,PSME2,TM9SF1,ARHGAP5,DHRS1,SCFD1,STXBP6,COCH,HECTD1,FITM1,G2E3,CMA1,DCAF11,CBLN3,EMC9,NOVA1,NEDD8 |
| 2.164e-02 | -3.83 | regulation of neurotransmitter transport | biological process | GO:0051588 | 99 | 39 | 18204 | 5365 |
CASK,RIMS4,STXBP1,GPM6B,SYP,SYNGR3,RIMS3,PPFIA2,HCRT,NLGN1,PREPL,SNAPIN,VPS18,CACNB4,SLC38A2,PRKCB,CPLX2,ASIC1,DRD1,RAP1A,BGLAP,SLC4A8,MEF2C,RAP1B,SNCG,P2RY4,P2RY1,WNT7A,RAB3B,CPLX1,CPLX3,RAB5A,STX1A,SV2B,SYT4,ATP1A2,FLOT1,DRD3,RAB3A |
| 2.164e-02 | -3.83 | CYTOCHROME_P450 | prosite domains | PS00086 | 53 | 22 | 12186 | 3388 |
CYP4F12,CYP11B2,CYP2C8,CYP11B1,CYP1B1,CYP2D6,CYP7A1,CYP26A1,CYP1A1,CYP3A5,CYP2R1,CYP4V2,CYP4F8,CYP2F1,CYP27B1,CYP21A2,CYP4F22,CYP17A1,CYP2C9,CYP2C18,CYP27A1,CYP3A43 |
| 2.168e-02 | -3.83 | SUCLG1 (succinate-CoA ligase GDP/ADP-forming subunit alpha) | protein interactions | 8802 | 116 | 43 | 19454 | 5460 |
SUCLG2,ACTB,MDH1,UBE2H,SPOP,GMPS,CFL2,PMPCA,AUH,MYC,HSPA5,GRPEL1,NT5C3A,OXCT1,FBXW7,HSCB,HSPA8,EXD2,SOD1,CDK7,STXBP1,NDUFAB1,EGLN3,CCAR2,GATD3,SDHB,SERPINC1,AIFM1,SSBP1,SNRNP70,RHOG,GSTO1,CTNNB1,ACP6,ABHD10,RIGI,REXO2,CHMP1B,HSPD1,SOD2,CCS,CMPK1,RAF1 |
| 2.173e-02 | -3.83 | coated vesicle membrane | cellular component | GO:0030662 | 204 | 73 | 19108 | 5553 |
GRIA1,STX5,GAD2,AP1G2,AP2S1,RAB3A,NECAP1,DIPK2A,CNIH1,HSPA8,LMAN1,ADRB2,KLHL12,NECAP2,FCGR1A,KDELR2,DNAJC5,AP2M1,RAB5A,VAMP2,ATP6V1G2,CD3G,TFRC,RAB35,ATP6V0B,GOSR2,TF,MYO6,RNASEK,TMED7,AP1M1,AP2A1,CLBA1,SGIP1,CIDEB,SYT2,ATP6V1D,ATP6AP2,SLC2A8,ARCN1,VTI1B,AFTPH,VAMP3,KDELR1,HBEGF,SLC30A5,COPE,VAMP8,NCALD,REEP6,TBC1D5,SEC13,VAMP7,TMEM199,CD4,CFTR,ATP6V1C1,CD9,SYNRG,ATP6V1A,SEC22B,FOLR1,STX17,COPZ2,B2M,LDLR,AP1S2,CD59,FZD4,TMED3,SEC23A,SAR1B,SLC32A1 |
| 2.178e-02 | -3.83 | NCAPD3 (non-SMC condensin II complex subunit D3) | protein interactions | 23310 | 141 | 51 | 19454 | 5460 |
SMC4,STAU1,HSCB,CXCR4,USP39,RPA2,CDK1,PRSS23,CCND1,SPTBN1,CDC42,FAXC,SYNE4,PSMD4,VIRMA,MAD2L2,ESR2,ENO1,LMBR1L,CCNF,EIF2S2,YWHAZ,PIP4K2C,BRCA1,RIC3,UBE2H,RIT1,PDCD4,CUL3,MCM3,NCAPG2,SEMA4C,KRAS,SOCS2,RPL31,RPS24,LDLRAD4,TP53,COMTD1,LGR4,PPP2R1A,SPTAN1,PRNP,SUMO2,FZR1,EGLN3,SPINT2,YWHAB,POU5F1,MOV10,DDRGK1 |
| 2.181e-02 | -3.83 | regulation of catecholamine secretion | biological process | GO:0050433 | 42 | 19 | 18204 | 5365 |
STX1A,ADORA3,CXCL12,HTR2A,KCNB1,KCNA2,P2RY1,GABBR1,SNCG,CHRNB2,CNR1,DRD3,OXTR,CARTPT,CHGA,SYT4,PRKCB,GRM2,OPRK1 |
| 2.181e-02 | -3.83 | positive regulation of phospholipase activity | biological process | GO:0010518 | 42 | 19 | 18204 | 5365 |
KIT,APOC2,PLA2G5,S1PR4,HTR2A,ADRA1A,LPAR1,CCL5,FGFR1,PHB1,CD86,ITK,HRAS,GNAQ,PLAA,PLCB2,LPAR2,AVPR1B,PHB2 |
| 2.181e-02 | -3.83 | amino sugar metabolic process | biological process | GO:0006040 | 42 | 19 | 18204 | 5365 |
CMAS,NANP,UAP1,GNPNAT1,EXTL2,DPAGT1,CSGALNACT1,CHST7,MGAT1,ST3GAL1,CHI3L1,OVGP1,GNPDA2,GNPDA1,CHST2,GFPT1,CHST1,ST6GAL1,LARGE1 |
| 2.181e-02 | -3.83 | purine nucleotide transport | biological process | GO:0015865 | 42 | 19 | 18204 | 5365 |
SLC25A4,SLC25A24,SLC25A23,LRRC8C,LRRC8B,GJB1,ANKH,SHOC2,SLC25A51,SLC25A17,SLC25A5,LRRC8A,SLC25A31,LRRC8D,ABCC5,CD47,SLC35B3,CALHM3,SLC25A42 |
| 2.181e-02 | -3.83 | regulation of amino acid transport | biological process | GO:0051955 | 42 | 19 | 18204 | 5365 |
ADORA1,SLC12A2,SLC38A3,RGS2,GABBR1,TNF,STXBP1,SLC6A1,SLC43A2,ATP1A2,CLTRN,ARL6IP5,PSEN1,LEP,NPY5R,SLC38A1,GRM2,SLC38A2,SYT4 |
| 2.184e-02 | -3.82 | Fluoxetine Action Pathway | SMPDB pathways | SMP0000426 | 31 | 18 | 1369 | 531 |
CYP2D6,SCN1B,CYP3A5,HTR1A,DRD1,ADRA1A,ATP1A3,ATP1B3,ATP1B1,OPRM1,KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3,CYP2C9 |
| 2.185e-02 | -3.82 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 1681 | 532 | 18204 | 5365 |
PGAP4,CNP,FHIT,NEK7,IL21,NDUFV2,MAP3K3,HADHA,GNAI3,STK4,IDO1,GNPTG,PIGC,TLR4,MPP1,SORD,TSSK1B,ENO2,CDK6,IP6K1,PTPN11,PIP4P1,INPP4A,CCL11,HSPA8,ACSS2,PTPN1,NDUFAB1,PTPRQ,TMEM38B,PLPP4,FGFR1,MTHFD2L,HEXB,FAR2,PLAAT5,ADCK1,OSBPL8,ATP5F1E,ITK,AK3,GPHN,PTPN4,IKBKB,PLPPR1,GAPDH,HINT1,CLN8,PPP2R3A,TAMM41,NUDT7,CSNK1A1,PAPSS2,LIPA,IRAK4,TNFAIP8L3,CAMKV,PPP2R1A,PRKCQ,HDHD5,SLA2,STK24,SDHC,PDE9A,BPNT2,NQO1,PRKX,NEK9,CDK8,ROCK2,PPT1,DUSP18,RAF1,PLAAT3,SHMT1,MAP3K11,MAPK10,DUSP10,FBP1,FITM1,GTPBP1,ABHD5,CAB39,EPHB6,ATP5MK,CDK5,BCKDK,CERK,EPHA2,MTMR12,ORMDL3,OGG1,STRADB,FDFT1,ELOVL1,PTPMT1,NUDT3,TYMS,GUCY1B1,FBXW11,TAFAZZIN,ILK,DCTD,ELOVL6,CDK9,SPHK2,TOP1,FRA10AC1,INPPL1,ACOT8,MAPKAPK3,CSNK2B,PLSCR1,SDHB,PIP4K2C,ACVR1,STK38L,DDR1,PDHA1,PPM1D,PRKCA,DUSP19,SLC25A1,SOCS2,G6PC3,PGAP3,PLA2G4B,DAPK1,CREB1,IGF1R,ALDH1L1,IER3,CSNK1E,PPP2R5E,MTMR6,DYRK2,HACD2,NUDT18,TLR3,EPHA4,MMUT,PTP4A2,DNAJC30,FITM2,CASK,FMO2,STK3,CTDSP2,GDE1,CDK5R1,GLYAT,MAP3K12,NDUFB7,PDE7A,NDUFA12,SOCS4,RPS6KA4,CDK1,INPP5K,HTR2A,ISYNA1,ATP5F1A,NDUFS8,SMPD2,ACOT6,PTPRZ1,NME4,PIM2,LDHB,CSNK1G3,AK2,SSH3,TAB1,TNKS,DCTPP1,SOCS3,ATP6V1A,PRDX4,SLC20A1,COQ8B,PPP1CB,MTM1,PLPP6,SLC19A2,DTYMK,IGFBP3,PDP2,ATP5PO,NDUFC2,ABHD12,IL4,SOCS5,NUDT5,PGAP2,NUDT2,HYCC1,ATP5F1B,ATP5MG,OSBP,PAK6,DUSP3,MAP2K3,PDE1A,RPIA,PLSCR3,SRPK2,SULT1A3,PDHB,FAM20C,PLA2G15,OLA1,DYRK1A,PXYLP1,PGAM1,SEPHS1,FMO1,ABHD14B,PDE8A,GDPD3,PTPN22,LDHA,NDUFA1,IDH1,SNRK,SLC19A3,PPP1CC,PRKCB,MAP2K1,CTBP1,MAP3K14,DNPH1,PPTC7,CTTNBP2NL,TLR7,DLG1,MVD,ETNK2,CDK7,ATP1A2,NDUFA2,ATP1B1,HYCC2,BECN1,TNNI3K,ATP5PF,BAZ1B,PLA2G12A,TECR,CSNK2A1,HCST,GPX4,PTPN5,DHRS7B,GNPAT,SERINC1,DLST,TESK2,PGM1,ROCK1,STK16,FIG4,ADK,NDUFS2,GMPS,MAP3K21,NUDT4,PIK3CA,ATP5PB,BIRC5,NMRK1,PAFAH1B1,ELOVL3,LEP,IDH2,PIK3CG,PDE4B,VAC14,ATP5MC3,PLCB2,COX11,SRC,NT5C3A,CDK20,MTMR2,NME1,NDUFB10,PRRT1,CMPK1,SMUG1,UBASH3B,PPM1K,SAMHD1,HMGCS1,VRK1,BMPR2,CLK1,MECP2,ALPL,RRM1,PPM1B,FABP5,HACD1,PPM1G,SACM1L,NUDT16,BMPR1A,IL15,NDUFB4,PTDSS1,PGS1,CAMK1,NDUFB8,AK5,NTRK2,PIGY,PGK1,ELOVL4,NTRK3,SLC52A3,YWHAZ,PIGK,PRKACB,SLC30A5,STYK1,NDUFS6,CDK17,SBK2,PIK3R2,AGK,RAN,PIK3R1,DUSP1,YES1,PRKAB1,ABHD16B,GPAM,GPAA1,DUSP22,WEE2,UCKL1,SARM1,NT5C2,STK38,STK11,DPM2,NDUFA5,NME2,PRDX6,PCYT1B,CISH,ACVR1B,GK2,PPAT,SYK,THTPA,PIGA,CACNB4,ATP5F1D,TESK1,NDUFB5,NUDT9,PDE2A,UCK1,MAPKAPK5,UGP2,CCL2,DUSP6,BMPR1B,CLPX,NPPC,MAP2K6,UMPS,CDK4,TRIB1,BPGM,ACAT1,TBK1,CSNK1A1L,PICK1,PTHLH,UBLCP1,CHKB,ENTPD4,TLR2,SELENOI,G6PD,DUSP9,TPST1,FAM20B,NUDT12,CD38,DMPK,SGMS2,NEK2,PPM1M,SEPHS2,PTP4A3,CDIPT,BGLAP,CSK,AGPAT1,ABHD6,NANP,NDUFB6,FGR,ABHD4,SUCLG2,RNASEL,NIM1K,FBP2,STOML2,ACSL4,ACVR1C,RAB23,DAPK3,PAK5,UCK2,UPRT,GPD2,SULT1B1,IMPA2,OXSR1,AGPAT5,DLAT,AKT3,ENO1,UHMK1,COPS2,PNP,PPP2CB,GGPS1,PPP1R12A,AKT2,NDUFS3,PRKAG1,NUS1,PNPLA8,PIGW,ACP6,NUDT19,DUSP21,DSTYK,ELOVL7,ENTPD3,DCAKD,ADCY3,REXO2,PC,ADSS2,GFPT1,PSKH1,SRD5A3,TNIK,LPCAT3,MDH1,CDKN3,OCRL,PHKG1,GUK1,JAK1,MFN1,OGDHL,PPP2R5A,PRPSAP1,ADM2,ORMDL1,PLCB1,PCK2,ATP5PD,INPP5E,PRPS1,NPR2,DUSP14,KARS1,CAMK2G,GK5,PIP4P2,PRKD3,CRYL1,PIK3R3,SGMS1,UCP2,UQCC3,CLK4,PFKFB2,FKRP,SDHAF2,MAPK4,DUSP26,DYRK1B,AKT1,CLP1,PPP3CA,ACP2,CDC7,ACACA,BAD,DCK,GSK3A,FN3KRP,PRKCE,ADCY2,ATP5MC1,SLC25A10,AKR1A1,PLA2G5,PCSK9,ACP5,NR1H2,JAK2,PTEN,PPP5C,PIP5K1A,CDKL2,PPP3R2,CKB,RPE,TGFBR2,STK26,PLAA,TP53I3,PAK2,CDK12,CTDSP1,KIT,EIF2AK2,MET,TOLLIP,COQ8A,DOLK,PNPO,RIOK2 |
| 2.187e-02 | -3.82 | regulation of phagocytosis | biological process | GO:0050764 | 102 | 40 | 18204 | 5365 |
CD47,ADIPOQ,IL15,CCL2,LYAR,CALR,PIP4P2,PLA2G5,FCER1G,ATG3,IFNG,FGR,FCN2,IL2RB,CD36,CSK,RAB31,CLEC7A,IL15RA,FCGR2A,IL2RG,RAB27A,FCGR1A,MIR20A,MBL2,MIR17,SYK,ITGAV,HMGB1,HSPA8,MIR183,TLR2,SNX3,FCGR2B,SFTPD,ITGA2,STAP1,PLSCR1,SOD1,PYCARD |
| 2.187e-02 | -3.82 | antimicrobial humoral immune response mediated by antimicrobial peptide | biological process | GO:0061844 | 102 | 40 | 18204 | 5365 |
GAPDH,RNASE6,FAU,CX3CL1,SPAG11B,XCL1,CXCL9,ROMO1,CXCL10,CCL2,CCL5,CXCL8,H2BC11,REG1A,CCL24,CXCL11,CCL4L1,CAMP,H2BC12,CCL18,DEFB1,CCL17,CCL25,LEAP2,FAM3A,CCL1,CCL23,CCL3,CCL21,REG1B,CCL20,CXCL1,CXCL14,RPL39,CXCL3,CCL11,CXCL13,F2,CCL8,CCL19 |
| 2.190e-02 | -3.82 | ZFP36 (ZFP36 ring finger protein) | protein interactions | 7538 | 179 | 63 | 19454 | 5460 |
LSM14B,IGF2BP1,RC3H2,CCDC85B,CEP85,SFN,DYRK1A,PRRC2A,SMAP2,CNOT6,MIR16-1,LARP4B,CCL3,RBMS2,CXCL8,AGO1,PRMT2,MED30,TANK,SUFU,ATG16L1,PRR5L,EIF4E,ZDHHC17,YTHDF1,HMGB1,FBXW7,HDAC3,SMG5,LSM12,YWHAB,EDC3,YWHAG,CNOT8,XPO1,YWHAH,CPEB1,CNOT2,MOV10,NFKB1,COMMD6,CDK6,FUBP3,PPP2CB,EIF4E2,WDR6,GLE1,TFRC,EXOSC8,TRAF2,YTHDF2,TNRC6C,TOP3B,TBK1,CNOT6L,TNF,CNOT7,DCP2,FHL3,ZC3H7A,GARRE1,PABPC1,HNRNPA2B1 |
| 2.194e-02 | -3.82 | HEATR1 (HEAT repeat containing 1) | protein interactions | 55127 | 211 | 73 | 19454 | 5460 |
FAM234A,DUSP14,PSMB3,TANK,CDC42,POLR1D,PPARG,RPA2,VAPB,STOM,GRM2,UTP15,RPA3,CD40,NLE1,PML,SIRT7,NPTN,STAU1,ARHGEF39,AATF,MYC,GPR17,CUL3,DNAJB6,ILK,LMBR1L,SCN2B,CCNF,ZNF330,PELO,TNFRSF9,IL2RA,PTPMT1,SNRNP40,APEX1,VIRMA,ESR2,COMTD1,MGARP,SOX2,LGR4,CBX3,SKA3,CA14,HDAC11,RND3,RHOBTB1,NUPR1,RPL31,SNIP1,EFNB1,RPS24,KRAS,PSMA5,PSMA2,RIGI,HS2ST1,PSMD3,GRSF1,IFI16,FAM174A,LAMP3,P2RY10,DDRGK1,DDX23,CHCHD1,STYK1,BRD3,CD274,EED,PTP4A3,ILVBL |
| 2.195e-02 | -3.82 | fatty-acyl-CoA biosynthetic process | biological process | GO:0046949 | 26 | 13 | 18204 | 5365 |
ELOVL4,ACAT1,ELOVL1,SLC25A1,ACACA,ELOVL3,ACSL4,TECR,ELOVL6,HACD2,HACD1,PPT1,ELOVL7 |
| 2.195e-02 | -3.82 | regulation of amyloid precursor protein biosynthetic process | biological process | GO:0042984 | 26 | 13 | 18204 | 5365 |
MIR147A,NCSTN,MIR153-1,AATF,MIR17,ITM2A,MIR20A,MIR106A,ITM2B,MIR101-1,MIR455,MIR298,MIR31 |
| 2.195e-02 | -3.82 | muscle cell cellular homeostasis | biological process | GO:0046716 | 26 | 13 | 18204 | 5365 |
CFL2,ANKH,PLG,SOD1,MSTN,MTM1,FXN,TRIM32,LAMP2,BAG3,LARGE1,CAV1,PLN |
| 2.195e-02 | -3.82 | positive regulation of glycoprotein metabolic process | biological process | GO:1903020 | 26 | 13 | 18204 | 5365 |
IL15,CCL21,IGF1,PLCB1,PXYLP1,CHP1,RAB1B,CCR7,RAB1A,NCSTN,CCL19,POMT2,CTNNB1 |
| 2.195e-02 | -3.82 | C4-dicarboxylate transport | biological process | GO:0015740 | 26 | 13 | 18204 | 5365 |
SLC1A1,SLC16A1,SLC25A10,LRRC8C,LRRC8B,SLC1A2,SLC25A11,SLC1A3,LRRC8A,LRRC8D,UCP2,SLC13A5,SLC25A12 |
| 2.195e-02 | -3.82 | regulation of positive chemotaxis | biological process | GO:0050926 | 26 | 13 | 18204 | 5365 |
AGER,VEGFC,ITGA2,NTRK3,FGF10,CDH13,VEGFA,CXCL12,SCG2,SMAD3,CXCL8,F7,CCR4 |
| 2.195e-02 | -3.82 | negative regulation of RNA splicing | biological process | GO:0033119 | 26 | 13 | 18204 | 5365 |
RPS26,HNRNPK,SRSF4,SRSF7,SRSF10,HNRNPA2B1,SRSF12,SAP18,DYRK1A,TMBIM6,PCBP4,RBM42,RPS13 |
| 2.195e-02 | -3.82 | activation of adenylate cyclase activity | biological process | GO:0007190 | 26 | 13 | 18204 | 5365 |
TMIGD3,RXFP2,CRHR1,LGR4,ADRB2,CAP2,DRD1,P2RY11,ADORA3,RAF1,EDNRA,TSHR,ADRB3 |
| 2.195e-02 | -3.82 | Chaperonin-mediated protein folding | REACTOME pathways | R-HSA-390466 | 99 | 41 | 10285 | 3229 |
CCT8,GNG13,GNG3,GNAI3,GNG5,GNG11,FBXW4,GNAO1,GNG10,CCT2,GNAI2,TUBA1A,PDCL,ACTB,RGS6,PFDN2,GNAZ,CSNK2B,GNB3,GNGT2,GNB1,PFDN5,TP53,CSNK2A1,PFDN1,GNB4,GNG7,CCT5,GNG12,TCP1,HDAC3,WRAP53,GNG2,FBXW7,TUBB4B,PFDN4,FBXL3,CCT7,MIR197,PFDN6,TUBA1B |
| 2.198e-02 | -3.82 | Autophagy - animal | KEGG pathways | hsa04140 | 127 | 55 | 7161 | 2463 |
KRAS,PTEN,SNAP29,PIK3R1,CTSD,AKT1,PIK3R2,ATG4A,RAB33B,MAPK10,BCL2L1,SH3GLB1,BECN1,ATG16L1,AKT2,ATG4C,VMP1,GABARAP,RRAGA,EIF2S1,RB1CC1,ATG9A,PIK3R3,PIK3CA,DDIT4,ATG7,GABARAPL1,BAD,DAPK1,STX17,IGBP1,ATG3,NRBF2,RRAGB,HRAS,TP53INP2,PPP2CB,PRKACB,PRKCQ,RAF1,IGF1R,STK11,CTSB,MAP2K1,TRAF6,GABARAPL2,LAMP2,AKT3,RHEB,RRAS2,HMGB1,VAMP8,MRAS,ATG101,DAPK3 |
| 2.198e-02 | -3.82 | Autophagy - animal | KEGG pathways | ko04140 | 127 | 55 | 7161 | 2463 |
NRBF2,ATG3,IGBP1,STX17,RRAGB,TP53INP2,HRAS,CTSB,IGF1R,STK11,PPP2CB,PRKCQ,RAF1,PRKACB,GABARAPL2,TRAF6,MAP2K1,AKT3,LAMP2,MRAS,ATG101,RRAS2,RHEB,HMGB1,VAMP8,DAPK3,CTSD,PIK3R1,SNAP29,KRAS,PTEN,PIK3R2,AKT1,ATG4A,SH3GLB1,BCL2L1,MAPK10,BECN1,RAB33B,VMP1,AKT2,ATG16L1,ATG4C,RB1CC1,ATG9A,RRAGA,GABARAP,EIF2S1,PIK3R3,DAPK1,PIK3CA,BAD,GABARAPL1,ATG7,DDIT4 |
| 2.201e-02 | -3.82 | ARHGEF7 (Rho guanine nucleotide exchange factor 7) | protein interactions | 8874 | 113 | 42 | 19454 | 5460 |
RIGI,SKP1,PFDN1,TGFBR2,FBXW7,HUWE1,FXR2,ATP5IF1,ARHGEF6,RHOU,ZYX,GIT2,PAK2,CDC42,TIMM13,LPXN,ZNHIT1,VIRMA,ERLIN1,PSMB6,RHOJ,PYGM,RAC2,SH2D1A,IGBP1,ZBTB33,CCNF,HSPB1,TRAPPC4,MED4,KPNA1,CBL,NCKIPSD,KLHL1,ICAM1,TRAPPC2L,KDM2A,NCK1,EXOC1,YWHAG,YWHAH,TAX1BP3 |
| 2.201e-02 | -3.82 | MYL12B (myosin light chain 12B) | protein interactions | 103910 | 113 | 42 | 19454 | 5460 |
KBTBD4,MYLIP,WDR77,ISG15,GABRA1,DDX39A,CBX3,CHMP4C,HEXIM1,MYL6,DDX39B,FOXD3,UFL1,CRYL1,STAU1,MEPCE,FBXO25,MRPS18C,IMMP2L,RIGI,MYC,HDAC6,BTF3,AR,DDRGK1,CTNNB1,MYO6,CBL,HTRA2,FOXP1,SETD7,HSPB1,CCNF,UBE2N,TES,EFCAB7,TRIM24,DAPK1,LGALS3,CDK9,ZBTB2,ESR2 |
| 2.201e-02 | -3.82 | KIRREL1 (kirre like nephrin family adhesion molecule 1) | protein interactions | 55243 | 113 | 42 | 19454 | 5460 |
ATG16L1,CLDN4,CDC42,MGARP,RND2,RAB4A,AQP3,NUPR1,RND3,RHOU,RAB5A,TACR1,PICK1,KRAS,FLOT1,TACR3,STX7,PRMT6,RAB11A,RAB5C,SAV1,RAB2A,DNAJC5,MYO6,DCAF4,RHOB,RHOG,LAMTOR1,HRAS,CD79B,RAB35,LMBR1L,ARL11,RAC2,GJA1,RHOH,RHOJ,ARF6,CAV1,VIRMA,DUOXA2,DIRAS3 |
| 2.201e-02 | -3.82 | MED28 (mediator complex subunit 28) | protein interactions | 80306 | 113 | 42 | 19454 | 5460 |
CDK8,MED23,KLHL12,MED31,POLR2D,POLR2C,POLR2G,MED9,MED30,RPAP2,FBXL19,PIK3R2,FBXW7,MED11,KRAS,NF2,TRIP4,STX8,MED13L,ATG3,MED29,MED21,MED10,MED27,RIT1,MED4,MED22,PRMT6,PIK3R1,MOV10,INSYN1,PSMD1,YES1,MED17,POLR2I,SRC,CDK9,POLR2B,POLR2L,DLG4,GTF2B,RAP1B |
| 2.201e-02 | -3.82 | NAP1L4 (nucleosome assembly protein 1 like 4) | protein interactions | 4676 | 195 | 68 | 19454 | 5460 |
KBTBD4,E2F4,ASPM,AURKAIP1,SOX2,EZH2,H2BC1,CAPZA2,CHMP4C,MOB3C,RPL18,RPL31,RPL23A,HSD17B10,COX8A,H1-6,PTPN4,MEPCE,EIF3E,UTP25,MOV10,KARS1,XPO1,CSNK2A1,H2AC4,CDC23,SSX2IP,H2AZ1,NAP1L5,CD274,CCDC71,MAGED2,TES,CAND1,EGLN3,PTP4A3,TSPYL4,DIRAS3,HMG20A,ATG16L1,DUSP22,H2BC11,HEXIM1,PIH1D1,BAP1,PPM1G,LCA5,SOD1,HSPA8,EP300,CFDP1,CDC16,RAB11A,CUL3,VAMP5,CDKN3,BTF3,BICD2,FTSJ3,H1-1,CCNF,ZNF330,ENO1,CTNNA1,GSK3A,GTF2F1,MATR3,APEX1 |
| 2.202e-02 | -3.82 | Transcription of the HIV genome | REACTOME pathways | R-HSA-167172 | 77 | 33 | 10285 | 3229 |
TAF2,SUPT5H,POLR2B,NCBP2,MNAT1,GTF2E1,CDK7,GTF2E2,TCEA1,GTF2H2,POLR2D,GTF2H5,POLR2L,POLR2G,ELOC,SUPT4H1,TAF9,GTF2A2,GTF2F2,POLR2F,TAF7,TAF10,ERCC3,SSRP1,GTF2B,TAF11,CDK9,GTF2F1,POLR2I,CCNH,POLR2C,GTF2H4,GTF2A1 |
| 2.203e-02 | -3.82 | SOX5 (SRY-box transcription factor 5) | protein interactions | 6660 | 160 | 57 | 19454 | 5460 |
RPS11,ZBTB26,ILF2,MTA3,ZMYM4,MSX2,SMAD1,EGR2,ZNF581,SOX2,TRAF2,SATB1,G3BP1,ZNF609,PAX6,FLOT1,POLDIP3,FOXP4,RPS13,LSM14A,EWSR1,SMCHD1,MED27,FOXP1,RPS2,CDC23,TLE1,KLHL9,CCAR2,BRMS1L,HMG20A,ZNF7,SSBP1,CDK6,ZHX1,MRPS34,KLF3,IRF2BPL,FTH1,PHB2,FOXP2,TTC1,IGF2BP1,CEP85,SEC13,HNF1B,LMO2,RPL39,RPS17,SMAD5,PRRC2A,ATXN1L,VPS72,ZHX3,UBE2I,TRIM24,QSER1 |
| 2.203e-02 | -3.82 | VPS26A (VPS26 retromer complex component A) | protein interactions | 9559 | 160 | 57 | 19454 | 5460 |
P2RY1,MUL1,CRTAP,TBC1D5,KXD1,NFKB1,VPS26A,CITED1,CD99L2,SNX2,VPS26C,MIF,SNX1,CORO1C,APEH,EZH2,PNMA2,BCS1L,NAA15,UBL4A,AHCYL1,KRAS,TTC4,VPS26B,GPSM3,IRF6,RIT1,PSMG3,SNX5,CRLF3,H1-10,RIOK2,MYC,COX6B1,NIBAN2,MORF4L1,LRRC73,UBE2V2,NMI,STAT1,SNX3,EIF2S2,S100A6,MOG,ZER1,VPS4B,P3H1,RPA2,EHD1,FAXC,ETF1,CERS2,ADRB2,RPL4,HSPA8,EEIG2,RPA3 |
| 2.207e-02 | -3.81 | response to interleukin-1 | biological process | GO:0070555 | 105 | 41 | 18204 | 5365 |
PRKCA,PLCB1,CD38,GCLC,CCL3,TOLLIP,SRC,GHR,TRAF6,MYD88,SOX9,IRAK4,IL1B,CD40,RPS6KA4,NKX3-1,TRIM63,PYCARD,IGBP1,MIR146A,TANK,IL1RAP,NFKBIA,CXCL8,CCL5,CD47,EPO,CHI3L1,CCL2,MIR101-1,EGR1,MIR204,IKBKB,AKAP12,TAF9,NFKB1,HYAL2,SFRP1,CAMP,CITED1,MIR142 |
| 2.208e-02 | -3.81 | INF2 (inverted formin 2) | protein interactions | 64423 | 279 | 94 | 19454 | 5460 |
DNAJB4,TMT1A,KRAS,TUBA1A,DNAJC25,TOP3B,MOB3C,RAB4A,RPN1,VPS33A,STIM1,GJA1,RAB35,HNRNPL,PPFIBP1,LAMP2,IFI16,NAB2,RHOG,RLIM,RAB5A,AKAP1,HSPA8,STX7,PXMP2,NEK7,SEC62,PPP1CB,OTULINL,TOMM22,CPLX2,NACC2,AP1G2,SEC61B,RMDN3,LMBR1L,FAM91A1,S100A6,ESR2,ACTB,DYNLL1,SSH3,BAG3,BTF3,RAB11A,MYC,FIS1,IGF1R,VPS16,FKBP8,RAB3B,CAMK2G,MTCH2,NUPR1,CAPZA2,ACTR2,TFRC,RAC2,HSD17B11,ADD1,PTPN1,STX6,TMPO,PRNP,DNAJC1,CSNK2A1,HDAC6,SLC25A46,MOV10,SMG8,DERL1,RAB9A,RPA3,TUSC2,TOMM20,ARMCX5,ST7,CDC42,SSR1,RPA2,STUB1,CCNF,CEP97,UBB,SLC25A31,COPE,TMOD3,PPP1CC,FBXO7,TRIM32,HERC4,NRP1,UHMK1,SPOP |
| 2.210e-02 | -3.81 | Baiap2 (brain-specific angiogenesis inhibitor 1-associated protein 2) | protein interactions | 108100 | 3 | 3 | 19454 | 5460 |
DLG4,DLG3,STUB1 |
| 2.210e-02 | -3.81 | Eif3l (eukaryotic translation initiation factor 3, subunit L) | protein interactions | 223691 | 3 | 3 | 19454 | 5460 |
CCNF,YWHAZ,RRN3 |
| 2.210e-02 | -3.81 | STAG3L1 (STAG3 cohesin complex component like 1 (pseudogene)) | protein interactions | 54441 | 3 | 3 | 19454 | 5460 |
ACTL6B,AGTRAP,HNRNPL |
| 2.210e-02 | -3.81 | SPACA7 (sperm acrosome associated 7) | protein interactions | 122258 | 3 | 3 | 19454 | 5460 |
HSPB1,HAPSTR1,KRAS |
| 2.210e-02 | -3.81 | Tnfrsf1b (tumor necrosis factor receptor superfamily, member 1b) | protein interactions | 21938 | 3 | 3 | 19454 | 5460 |
BIRC2,TRAF2,TRAF1 |
| 2.210e-02 | -3.81 | CBLN3 (cerebellin 3 precursor) | protein interactions | 643866 | 3 | 3 | 19454 | 5460 |
CBLN2,CBLN4,CBLN1 |
| 2.210e-02 | -3.81 | ACER1 (alkaline ceramidase 1) | protein interactions | 125981 | 3 | 3 | 19454 | 5460 |
MPP1,UBA52,SOX2 |
| 2.210e-02 | -3.81 | ZNF534 (zinc finger protein 534) | protein interactions | 147658 | 3 | 3 | 19454 | 5460 |
C1QC,AGAP1,WDR83OS |
| 2.210e-02 | -3.81 | LINC02913 (long intergenic non-protein coding RNA 2913) | protein interactions | 414318 | 3 | 3 | 19454 | 5460 |
PDE9A,PSMG3,PSMA3 |
| 2.210e-02 | -3.81 | NIBAN3 (niban apoptosis regulator 3) | protein interactions | 199786 | 3 | 3 | 19454 | 5460 |
BAG3,MDFI,HSP90B1 |
| 2.210e-02 | -3.81 | DSPP (dentin sialophosphoprotein) | protein interactions | 1834 | 3 | 3 | 19454 | 5460 |
HEXIM1,DVL2,CSK |
| 2.210e-02 | -3.81 | OR2T35 (olfactory receptor family 2 subfamily T member 35) | protein interactions | 403244 | 3 | 3 | 19454 | 5460 |
BAG3,CFTR,CUL3 |
| 2.210e-02 | -3.81 | Rpl26 (ribosomal protein L26) | protein interactions | 19941 | 3 | 3 | 19454 | 5460 |
YWHAZ,CCNF,STUB1 |
| 2.210e-02 | -3.81 | LOC366310 (pseudogene for small nuclear RNA U3 (H3.9)) | protein interactions | 366310 | 3 | 3 | 19454 | 5460 |
PHAX,XPO1,NCBP2 |
| 2.210e-02 | -3.81 | RSPH10B (radial spoke head 10 homolog B) | protein interactions | 222967 | 3 | 3 | 19454 | 5460 |
SOX2,MKLN1,SPPL3 |
| 2.210e-02 | -3.81 | Puf60 (poly-U binding splicing factor 60) | protein interactions | 67959 | 3 | 3 | 19454 | 5460 |
H3C1,JADE1,PTEN |
| 2.210e-02 | -3.81 | ABHD2 (abhydrolase domain containing 2, acylglycerol lipase) | protein interactions | 11057 | 3 | 3 | 19454 | 5460 |
LAMP5,HNRNPL,VIRMA |
| 2.210e-02 | -3.81 | ZC3H12B (zinc finger CCCH-type containing 12B) | protein interactions | 340554 | 3 | 3 | 19454 | 5460 |
IL6,PSMD14,IER3 |
| 2.210e-02 | -3.81 | Ahnak (AHNAK nucleoprotein) | protein interactions | 66395 | 3 | 3 | 19454 | 5460 |
CCNF,STUB1,PTEN |
| 2.210e-02 | -3.81 | BPY2 (basic charge Y-linked 2) | protein interactions | 9083 | 3 | 3 | 19454 | 5460 |
UBE3A,PPIA,MAP1S |
| 2.210e-02 | -3.81 | Rps3a1 (ribosomal protein S3A1) | protein interactions | 20091 | 3 | 3 | 19454 | 5460 |
PLEKHO1,CHIC2,CCNF |
| 2.210e-02 | -3.81 | Mtap (methylthioadenosine phosphorylase) | protein interactions | 66902 | 3 | 3 | 19454 | 5460 |
EFHD2,CCNF,PTEN |
| 2.210e-02 | -3.81 | Ube4b (ubiquitination factor E4B) | protein interactions | 63958 | 3 | 3 | 19454 | 5460 |
UBE2D3,CCNF,UBE2W |
| 2.210e-02 | -3.81 | Rsl1d1 (ribosomal L1 domain containing 1) | protein interactions | 66409 | 3 | 3 | 19454 | 5460 |
TFIP11,JADE1,CCNF |
| 2.210e-02 | -3.81 | ADAMTS16 (ADAM metallopeptidase with thrombospondin type 1 motif 16) | protein interactions | 170690 | 3 | 3 | 19454 | 5460 |
SERPINH1,ARL11,TOP1 |
| 2.210e-02 | -3.81 | HSP90AA1 (heat shock protein 90 alpha family class A member 1) | protein interactions | 281832 | 3 | 3 | 19454 | 5460 |
AIPL1,TP53,WASL |
| 2.210e-02 | -3.81 | Ugdh (UDP-glucose dehydrogenase) | protein interactions | 22235 | 3 | 3 | 19454 | 5460 |
CCNF,YWHAZ,PTEN |
| 2.210e-02 | -3.81 | Idh1 (isocitrate dehydrogenase 1 (NADP+), soluble) | protein interactions | 15926 | 3 | 3 | 19454 | 5460 |
PTEN,HSD17B10,CCNF |
| 2.210e-02 | -3.81 | SMIM21 (small integral membrane protein 21) | protein interactions | 284274 | 3 | 3 | 19454 | 5460 |
RMND1,CFTR,DESI1 |
| 2.210e-02 | -3.81 | FBXO36 (F-box protein 36) | protein interactions | 130888 | 3 | 3 | 19454 | 5460 |
SKP1,CDH11,KRAS |
| 2.210e-02 | -3.81 | ORF63 (regulatory protein ICP22) | protein interactions | 1487711 | 3 | 3 | 19454 | 5460 |
ASF1A,CCNB1,CDK1 |
| 2.210e-02 | -3.81 | Dnajc7 (DnaJ heat shock protein family (Hsp40) member C7) | protein interactions | 56354 | 3 | 3 | 19454 | 5460 |
CCNF,SMURF1,HSP90AA1 |
| 2.210e-02 | -3.81 | ACRV1 (acrosomal vesicle protein 1) | protein interactions | 56 | 3 | 3 | 19454 | 5460 |
CFTR,DDX39A,TRIM68 |
| 2.210e-02 | -3.81 | ARRDC5 (arrestin domain containing 5) | protein interactions | 645432 | 3 | 3 | 19454 | 5460 |
HSPB1,PDCD5,ERRFI1 |
| 2.210e-02 | -3.81 | Arf4 (ADP-ribosylation factor 4) | protein interactions | 11843 | 3 | 3 | 19454 | 5460 |
CCNF,YWHAZ,CFTR |
| 2.210e-02 | -3.81 | MDGA1 (MAM domain containing glycosylphosphatidylinositol anchor 1) | protein interactions | 266727 | 3 | 3 | 19454 | 5460 |
NLGN2,CDK5,LNX2 |
| 2.210e-02 | -3.81 | LDB19 (Ldb19p) | protein interactions | 854500 | 3 | 3 | 19454 | 5460 |
OTUD7B,STAMBP,USP2 |
| 2.210e-02 | -3.81 | Zfp128 (zinc finger protein 128) | protein interactions | 243833 | 3 | 3 | 19454 | 5460 |
SMAD3,SMAD4,SMAD5 |
| 2.210e-02 | -3.81 | NPIPB3 (nuclear pore complex interacting protein family member B3) | protein interactions | 23117 | 3 | 3 | 19454 | 5460 |
RIT1,MDM2,DDX39A |
| 2.210e-02 | -3.81 | INMT (indolethylamine N-methyltransferase) | protein interactions | 11185 | 3 | 3 | 19454 | 5460 |
KLHL12,LNX2,KRAS |
| 2.210e-02 | -3.81 | DDI1 (Ddi1p) | protein interactions | 856886 | 3 | 3 | 19454 | 5460 |
DDI1,UBB,DVL2 |
| 2.210e-02 | -3.81 | PAQR8 (progestin and adipoQ receptor family member 8) | protein interactions | 85315 | 3 | 3 | 19454 | 5460 |
EHHADH,MPP1,LEPROTL1 |
| 2.210e-02 | -3.81 | Hoxa2 (homeobox A2) | protein interactions | 15399 | 3 | 3 | 19454 | 5460 |
PSMA3,RCHY1,PSMB2 |
| 2.210e-02 | -3.81 | MORN1 (MORN repeat containing 1) | protein interactions | 79906 | 3 | 3 | 19454 | 5460 |
EP300,HNRNPL,TOP3B |
| 2.210e-02 | -3.81 | CYP27B1 (cytochrome P450 family 27 subfamily B member 1) | protein interactions | 1594 | 3 | 3 | 19454 | 5460 |
DDX39A,PSMG3,E2F4 |
| 2.210e-02 | -3.81 | Gapdh (glyceraldehyde-3-phosphate dehydrogenase) | protein interactions | 14433 | 3 | 3 | 19454 | 5460 |
STUB1,FAIM,HSD17B10 |
| 2.210e-02 | -3.81 | NUGGC (nuclear GTPase, germinal center associated) | protein interactions | 389643 | 3 | 3 | 19454 | 5460 |
FBXO22,POLD2,FEM1B |
| 2.210e-02 | -3.81 | Hk2 (hexokinase 2) | protein interactions | 25059 | 3 | 3 | 19454 | 5460 |
PTGDS,IGFBP4,ZBTB17 |
| 2.210e-02 | -3.81 | TAH1 (Tah1p) | protein interactions | 850424 | 3 | 3 | 19454 | 5460 |
HSP90AB1,HSP90AA1,ZBTB25 |
| 2.210e-02 | -3.81 | Zeb2 (zinc finger E-box binding homeobox 2) | protein interactions | 24136 | 3 | 3 | 19454 | 5460 |
SMAD1,SMAD2,SMAD3 |
| 2.210e-02 | -3.81 | Bag3 (BCL2-associated athanogene 3) | protein interactions | 29810 | 3 | 3 | 19454 | 5460 |
C9orf72,CCNF,CFTR |
| 2.210e-02 | -3.81 | SLC2A10 (solute carrier family 2 member 10) | protein interactions | 81031 | 3 | 3 | 19454 | 5460 |
SRC,ESR2,SPPL3 |
| 2.210e-02 | -3.81 | E1A (control protein E1A;control protein E1A 243R) | protein interactions | 2652980 | 3 | 3 | 19454 | 5460 |
CTBP1,RB1,CDKN1B |
| 2.210e-02 | -3.81 | Rps15 (ribosomal protein S15) | protein interactions | 20054 | 3 | 3 | 19454 | 5460 |
YTHDF1,YWHAZ,CCNF |
| 2.210e-02 | -3.81 | C8orf44 (chromosome 8 putative open reading frame 44) | protein interactions | 56260 | 3 | 3 | 19454 | 5460 |
DDX39A,CORO6,FBXW7 |
| 2.210e-02 | -3.81 | LINC01194 (long intergenic non-protein coding RNA 1194) | protein interactions | 404663 | 3 | 3 | 19454 | 5460 |
TP53,HNRNPL,CTNNB1 |
| 2.210e-02 | -3.81 | FREM1 (FRAS1 related extracellular matrix 1) | protein interactions | 158326 | 3 | 3 | 19454 | 5460 |
DVL2,KRAS,STK3 |
| 2.210e-02 | -3.81 | ANKRD34B (ankyrin repeat domain 34B) | protein interactions | 340120 | 3 | 3 | 19454 | 5460 |
DDX39A,HRAS,YWHAZ |
| 2.210e-02 | -3.81 | Rpl23 (ribosomal protein L23) | protein interactions | 65019 | 3 | 3 | 19454 | 5460 |
AKT1,CCNF,PTEN |
| 2.210e-02 | -3.81 | HJV (hemojuvelin BMP co-receptor) | protein interactions | 148738 | 3 | 3 | 19454 | 5460 |
SPPL3,ACACA,TMBIM6 |
| 2.210e-02 | -3.81 | Rapsn (receptor-associated protein of the synapse) | protein interactions | 19400 | 3 | 3 | 19454 | 5460 |
CSNK2A1,SMURF1,SRC |
| 2.210e-02 | -3.81 | DISP2 (dispatched RND transporter family member 2) | protein interactions | 85455 | 3 | 3 | 19454 | 5460 |
TOP3B,DDX39A,VIRMA |
| 2.210e-02 | -3.81 | DCHS2 (dachsous cadherin-related 2) | protein interactions | 54798 | 3 | 3 | 19454 | 5460 |
COPS5,DYRK1A,FBXO22 |
| 2.210e-02 | -3.81 | Rps3 (ribosomal protein S3) | protein interactions | 27050 | 3 | 3 | 19454 | 5460 |
CHIC2,CCNF,PTEN |
| 2.210e-02 | -3.81 | PHOX2B (paired like homeobox 2B) | protein interactions | 8929 | 3 | 3 | 19454 | 5460 |
FBXO22,PRKAB1,CREBBP |
| 2.219e-02 | -3.81 | KOW | interpro domains | IPR005824 | 9 | 6 | 18521 | 5414 |
RPL26L1,RPL27,RPL26,RPS4X,MRPL24,SUPT5H |
| 2.219e-02 | -3.81 | Glyco_trans_8 | interpro domains | IPR002495 | 9 | 6 | 18521 | 5414 |
GXYLT2,LARGE1,XXYLT1,GLT8D2,GLT8D1,GXYLT1 |
| 2.219e-02 | -3.81 | HIT-like_sf | interpro domains | IPR036265 | 9 | 6 | 18521 | 5414 |
HINT2,CWF19L1,HINT1,FHIT,APTX,HINT3 |
| 2.219e-02 | -3.81 | PAZ_dom | interpro domains | IPR003100 | 9 | 6 | 18521 | 5414 |
PIWIL3,PIWIL4,PIWIL2,AGO1,DICER1,PIWIL1 |
| 2.219e-02 | -3.81 | Activin_recp | interpro domains | IPR000472 | 9 | 6 | 18521 | 5414 |
ACVR1,BMPR1A,ACVR1C,BMPR1B,BMPR2,ACVR1B |
| 2.219e-02 | -3.81 | Bcl-2_fam | interpro domains | IPR026298 | 9 | 6 | 18521 | 5414 |
BCL2A1,BOK,MCL1,BAX,BCL2L1,BAK1 |
| 2.219e-02 | -3.81 | PAZ_dom_sf | interpro domains | IPR036085 | 9 | 6 | 18521 | 5414 |
PIWIL1,AGO1,PIWIL2,DICER1,PIWIL3,PIWIL4 |
| 2.222e-02 | -3.81 | neuronal cell body membrane | cellular component | GO:0032809 | 29 | 14 | 19108 | 5553 |
ATP1A3,HPCA,KCNA2,KCNB1,SLC4A8,GRIA1,AMIGO1,SLC6A3,TACR3,KCNC1,SLC6A2,KCND2,CX3CR1,THY1 |
| 2.222e-02 | -3.81 | smooth endoplasmic reticulum | cellular component | GO:0005790 | 29 | 14 | 19108 | 5553 |
STX17,ERP29,DNAJC3,RPL10,SVIP,GABARAP,CALR,SLMAP,SYVN1,PSEN1,JPH4,PPIB,HSP90B1,PGRMC1 |
| 2.222e-02 | -3.81 | phosphatidylinositol 3-kinase complex | cellular component | GO:0005942 | 29 | 14 | 19108 | 5553 |
PIK3R3,NRBF2,PIK3R1,SOCS5,VAC14,CISH,SOCS3,PIK3R2,PIK3CA,SOCS4,SOCS2,PIK3CG,SLA2,BECN1 |
| 2.224e-02 | -3.81 | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | 32 | 15 | 16828 | 4835 |
TP53,GNA11,KIT,CTNNB1,IDH2,AKT1,TERT,PIK3CA,PTEN,HRAS,KRAS,PIK3R1,IDH1,MAP2K1,GNAQ |
| 2.224e-02 | -3.81 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_primary_myelofibrosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_primary_myelofibrosis | 32 | 15 | 16828 | 4835 |
KRAS,HRAS,CBL,IDH1,CALR,SF3B1,RUNX1,SRSF2,TP53,KIT,IDH2,JAK2,FGFR1,EZH2,PTEN |
| 2.224e-02 | -3.81 | acute_leukaemic_transformation_of_primary_myelofibrosis | COSMIC cancer mutations | acute_leukaemic_transformation_of_primary_myelofibrosis | 32 | 15 | 16828 | 4835 |
CALR,RUNX1,SF3B1,HRAS,KRAS,CBL,IDH1,FGFR1,EZH2,PTEN,TP53,SRSF2,KIT,IDH2,JAK2 |
| 2.225e-02 | -3.81 | regulation of mitochondrial membrane potential | biological process | GO:0051881 | 73 | 30 | 18204 | 5365 |
LIPA,SLC25A27,ATP5IF1,SOD1,PPIF,ARL6IP5,IFI6,TSPO,RNF122,GCLC,MLLT11,SRC,PID1,MFN1,TUSC2,BAX,PMAIP1,PYCR1,BAK1,BNIP3L,BAD,SOD2,UBB,PRDX3,ALB,BCL2L1,UCP2,PRELID1,BOK,MUL1 |
| 2.225e-02 | -3.81 | positive regulation of TOR signaling | biological process | GO:0032008 | 73 | 30 | 18204 | 5365 |
PIK3CA,RRAGA,F7,SLC38A9,EP300,RRAGB,FLCN,PIH1D1,SEC13,STAMBPL1,LAMTOR2,HDAC3,CUL3,SYK,LAMTOR1,KLHL22,LAMTOR3,RHEB,AKT3,AKT1,MIOS,SESN2,SRC,PIP4P1,LEP,F10,RNF167,CSNK1A1,TBK1,GPR137 |
| 2.226e-02 | -3.81 | intercalated disc | cellular component | GO:0014704 | 51 | 22 | 19108 | 5553 |
YWHAH,PIK3CA,FGF13,RANGRF,DES,CTNNA1,ATP1A2,DLG1,SLC2A1,VAMP5,SLC8A1,SCN1B,CTNNB1,KCNJ11,SLC31A1,ATP1B1,MYH1,KCNJ2,JUP,GJC1,GJA1,CAV3 |
| 2.229e-02 | -3.80 | heat shock protein binding | molecular function | GO:0031072 | 130 | 50 | 18094 | 5411 |
CYP1A1,PACRG,NUP62,BAG2,PPP5C,RPS3,METTL18,DNAJC10,FAF1,HSPA5,TTC4,EEF1AKMT3,UNC45A,KCNJ11,DNAJC2,ST13,HSPA8,ETFBKMT,GUCY1B1,HSPA13,STUB1,METTL22,BAX,CHORDC1,BAK1,CDC37L1,DNAJB6,DNAJC7,DNAJC8,ADORA1,AHSA1,CDK1,FKBP4,METTL21A,HSP90AB1,SLC12A2,HSPA14,GPR37,CDKN1B,CSNK2A1,HDAC6,PTGES3,TFRC,MVD,HIKESHI,FGF1,DNAJB2,PPID,DNAJB9,CDK5 |
| 2.230e-02 | -3.80 | CLAUDIN | prosite domains | PS01346 | 22 | 11 | 12186 | 3388 |
CLDN12,CLDN22,CLDN11,CLDN6,CLDN1,CLDN9,CLDN24,CLDN14,CLDN4,CLDN3,CLDN8 |
| 2.233e-02 | -3.80 | CNOT11 (CCR4-NOT transcription complex subunit 11) | protein interactions | 55571 | 110 | 41 | 19454 | 5460 |
GPBP1L1,IZUMO1,VPS33A,RPA2,CAPZA2,ATG16L1,TOP3B,YTHDF2,TNRC6C,CNOT6L,TOB2,CAPZA1,G3BP2,CNOT7,YTHDF1,STAU1,ZC3H7A,GARRE1,MED4,UHMK1,FBXW11,GADD45B,RC3H2,XPO1,CNOT8,CPEB1,CNOT2,NFKB1,FAM193B,CEP85,EGLN3,CNTROB,DYRK1A,BTG3,PRRC2A,ESR2,FANCD2OS,PRNP,CCNF,FUBP3,CNOT6 |
| 2.241e-02 | -3.80 | NUDIX | pfam domains | PF00293 | 21 | 11 | 17795 | 5224 |
DCP2,NUDT3,NUDT2,NUDT12,NUDT7,NUDT5,NUDT18,NUDT9,NUDT16,NUDT1,NUDT4 |
| 2.241e-02 | -3.80 | pleomorphic | COSMIC cancer mutations | pleomorphic | 24 | 12 | 16828 | 4835 |
PIK3CA,TERT,PTEN,TP53,CTNNB1,RB1,KIT,FBXW7,EWSR1,KRAS,HRAS,IDH1 |
| 2.243e-02 | -3.80 | PRSS50 (serine protease 50) | protein interactions | 29122 | 44 | 19 | 19454 | 5460 |
DHRS7B,STK11,FKBP14,ADAMTS1,TUBA1A,KDELR2,SAMHD1,TOR3A,HSPA5,ESR2,TUBB,SPPL3,SFXN2,SPCS2,TSG101,PIGK,HRAS,DNAJC3,GPAA1 |
| 2.243e-02 | -3.80 | PGK2 (phosphoglycerate kinase 2) | protein interactions | 5232 | 44 | 19 | 19454 | 5460 |
POLL,HSPE1,GARIN2,ENO1,MAP1B,MSN,ASPA,TAGLN3,AKR1B1,INTS10,PGK1,FLCN,AKR1A1,UTP15,HOXC4,SHMT1,RPE,LRRC40,ZCCHC12 |
| 2.246e-02 | -3.80 | cell-cell contact zone | cellular component | GO:0044291 | 74 | 30 | 19108 | 5553 |
RAP2C,FGF13,YWHAH,RANGRF,DES,SLC2A1,FLOT1,VAMP5,SLC8A1,KCNJ11,SLC31A1,SCN1B,NECTIN2,ATP1B1,GJC1,PIK3CA,CTNNA1,PKP4,ATP1A2,DLG1,TIAM1,RAP2B,FLCN,CTNNB1,MYH1,KCNJ2,CAV3,PCDH9,JUP,GJA1 |
| 2.247e-02 | -3.80 | CREB1 (cAMP responsive element binding protein 1) | protein interactions | 1385 | 237 | 81 | 19454 | 5460 |
CPEB1,CSNK2A1,CTNNB1,HMGA1,FOXC2,NR4A2,AGR2,ZHX1,RFX5,LDLR,FEZ1,ZNF436,CEP19,CCT7,ZBTB2,TCP1,CRTC2,JUN,SOX9,SPC24,TP53,H2BC1,ERG28,TRIM21,TRIM11,FHL3,RAB1A,MRPL52,ZNF451,STRADB,CAPZA1,H3C1,TOLLIP,HNRNPK,CSGALNACT2,AR,ATF1,AKT1,HNF1B,CREBBP,SMARCA5,NFYA,PFDN4,PHF7,MECP2,BRCA1,RPS6KA4,GSK3A,CSNK2B,GTF2A1,ZMYM2,UBE2I,PTEN,GTF2F2,CREB1,RAN,ESR2,DYRK1A,KCNIP3,RBBP4,EDF1,TOM1L2,CCND1,SEC22B,NFYB,EIF4B,CDK1,TOX4,H2BC11,HPS6,TRIM5,CRY1,DR1,EP300,TRIM22,MIA2,ORC6,DNAJC3,HTR1A,PIAS1,NFIL3 |
| 2.251e-02 | -3.79 | TCR signaling in naive CD4+ T cells | Pathway Interaction DB | tcr_pathway | 60 | 29 | 2226 | 782 |
CDC42,CD4,CD86,PRKCB,PRKCE,CD80,CD28,SLA2,RAP1A,AKT1,CD3G,STIM1,CSK,PTPN11,IKBKB,ITK,CD247,SHC1,PTEN,NCK1,PRKCA,BCL10,LCP2,CBL,RASGRP2,PRKCQ,TRAF6,GRAP2,MAP3K14 |
| 2.251e-02 | -3.79 | early endosome membrane | cellular component | GO:0031901 | 195 | 70 | 19108 | 5553 |
ZMPSTE24,LAMP5,SYNDIG1,PLD3,STX7,CD274,TMEM30A,SLC11A2,B2M,MARCHF3,LITAF,DKK1,PSEN1,RAB14,TOM1,HPS6,SLC1A1,LDLRAD4,CLVS2,KCNH1,VAMP3,CMTM6,HSD17B6,TSG101,RAB31,TICAM2,CLVS1,CAV1,VAMP8,REP15,SLC31A1,OCRL,NSG1,PLEKHF2,OR51E2,SNX2,UBXN6,ARF6,SNX5,CFTR,EHD4,FCMR,NTRK2,LRP6,EPHA4,SNX12,SNX1,SNX3,RAB5C,EHD1,RAB4A,BOK,VTI1B,FIG4,GRIA1,PML,FGD2,CLIP3,INPP4A,GPNMB,VAC14,STX12,LAMP3,MTMR2,HGS,FCGR1A,SNX20,PLA2G4B,PDLIM4,RAB5A |
| 2.252e-02 | -3.79 | NASP (nuclear autoantigenic sperm protein) | protein interactions | 4678 | 192 | 67 | 19454 | 5460 |
MYC,CUL3,ST13,BAG3,XPOT,H1-1,UBE2H,CCNF,UBN1,PRMT5,GANAB,NDN,MATR3,FBXO22,RBBP4,MAT2B,ATP6V1C1,CDC42,NEK7,DCTN4,LMNA,RPA2,METTL14,UBE2M,CDAN1,BAP1,HIRA,RPA3,UPF3B,CRY1,EP300,FXR2,EMC1,SMC4,HMGB1,STAU1,BCL6,ATG7,HDAC6,CSTA,TIAM1,TRAF6,PPP3CA,USP15,FABP5,FZR1,SNX1,EGLN3,DKC1,E2F4,ACTR1A,MSX2,UBR7,CHMP4C,MTA2,POLR2G,MOB3C,HAPSTR1,ACTR1B,HUWE1,H3C1,RBBP7,ASF1A,KPNA2,MCM6,PSMD12,PTGES3 |
| 2.252e-02 | -3.79 | AATK (apoptosis associated tyrosine kinase) | protein interactions | 9625 | 192 | 67 | 19454 | 5460 |
TRAPPC4,PPM1K,HSPB1,PPP3CA,PPP1R11,PPM1B,NCK1,BAZ1B,KARS1,EPHB6,SLC25A12,AFTPH,EIF2S1,ATP6V1A,TRAPPC10,WDCP,MRTO4,UBE2N,DUSP6,EHBP1,CDK5R1,DUSP1,TOP3B,TP53,ARF4,FBXO11,CDK5,ACTR1B,FHL3,SLC25A10,NDUFA4,SLC25A11,HSP90AA1,AP2A1,SERPINH1,CCDC22,FBXW11,PPP1CC,SLC25A1,SMARCA5,PTPN11,PNP,TAB1,AP2M1,PPM1M,PTEN,MSN,FAM91A1,OXSR1,KLC2,SLC25A3,DCTN4,CDK1,PPP1CB,NTPCR,ETF1,CNP,SYNRG,DUSP14,MTMR6,PAFAH1B1,PPP1R8,PPP1R2,FXR2,DCTN3,DUSP9,DCTN6 |
| 2.252e-02 | -3.79 | signal sequence binding | molecular function | GO:0005048 | 47 | 21 | 18094 | 5411 |
KDELR1,TOMM40L,PEX5L,BRAP,NUP153,SRP54,KPNA2,KDELR2,RANBP6,TOMM22,TOMM20,AP2M1,KPNA6,SEC61A1,KCNIP2,TNPO2,NFKBIA,KPNA1,TOMM70,SRP14,SEC61A2 |
| 2.253e-02 | -3.79 | response to amino acid starvation | biological process | GO:1990928 | 56 | 24 | 18204 | 5365 |
DAP,KICS2,EIF2S1,RNF152,SESN3,MAP1LC3A,FLCN,SLC38A2,SH3GLB1,SAR1B,RRAGB,CDKN1A,UCP2,RRAGA,ATF4,TFEB,RNF167,ATF3,BECN1,SESN2,MIOS,FAS,EIF2AK2,IMPACT |
| 2.253e-02 | -3.79 | positive regulation of cell-matrix adhesion | biological process | GO:0001954 | 56 | 24 | 18204 | 5365 |
EMP2,CCL21,FUT1,JUP,DAG1,CCL25,S100A10,CDH13,CCR7,POLDIP2,GFUS,CDK6,THY1,SDC4,DISC1,NRP1,CCL28,CX3CL1,SMAD3,CD36,SFRP1,VEGFA,ROCK1,FERMT2 |
| 2.259e-02 | -3.79 | vesicle docking involved in exocytosis | biological process | GO:0006904 | 34 | 16 | 18204 | 5365 |
EXOC8,CPLX2,VAMP3,EXOC5,VPS18,GNAO1,SNAP25,YKT6,VTI1B,KCNB1,STXBP1,PPFIA3,CFTR,EXOC1,EXOC3,EXOC2 |
| 2.259e-02 | -3.79 | intra-Golgi vesicle-mediated transport | biological process | GO:0006891 | 34 | 16 | 18204 | 5365 |
TRAPPC10,RAB6A,COPE,NAPG,COPZ2,GABARAPL2,VTI1B,COG1,RAB6B,RAB33B,GOLGA5,TRAPPC3L,GOSR1,TRAPPC3,GOSR2,NAPA |
| 2.259e-02 | -3.79 | regulation of protein export from nucleus | biological process | GO:0046825 | 34 | 16 | 18204 | 5365 |
MDM2,IFI27,RBM22,SIRT7,ANP32B,CDK5,IL1B,CHCHD4,BAG3,XPO1,UHMK1,CTDSPL2,TXN,SFN,PTPN11,CAMK1 |
| 2.259e-02 | -3.79 | polysaccharide biosynthetic process | biological process | GO:0000271 | 34 | 16 | 18204 | 5365 |
CSGALNACT1,GYS1,PHKG1,FUT9,HS2ST1,NDST1,PPP1R3C,CSGALNACT2,AKT1,NDST3,GBE1,AKT2,PTGES3,EXT1,HAS3,UGP2 |
| 2.259e-02 | -3.79 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator | biological process | GO:1902253 | 34 | 16 | 18204 | 5365 |
TP53,KDM1A,MIR186,MIF,MDM2,MIR21,RPL26,RRN3,ING2,HNRNPK,UBB,MYC,TAF9,RPS7,USP15,MSX1 |
| 2.259e-02 | -3.79 | negative regulation of receptor signaling pathway via STAT | biological process | GO:1904893 | 34 | 16 | 18204 | 5365 |
MIR125A,MIR340,SOCS3,CAV1,CLEC12B,NF2,MIR874,MIR146A,SOCS2,MIR9-1,ADIPOR1,MIR99A,MIR149,MIRLET7C,PPARG,HGS |
| 2.261e-02 | -3.79 | human chr15q22.31 | chromosome location | human chr15q22.31 | 58 | 20 | 26134 | 5823 |
DIS3L,MAP2K1,KBTBD13,ZNF609,RASL12,TRIP4,HACD3,PPIB,SNX1,SNAPC5,PLEKHO2,SNX22,RAB11A,CLPX,PCLAF,OAZ2,MIR422A,SPG21,USP3,RPL4 |
| 2.262e-02 | -3.79 | GLUL (glutamate-ammonia ligase) | protein interactions | 2752 | 135 | 49 | 19454 | 5460 |
PLEKHF2,CCT7,FUNDC2,PREP,CRBN,USP15,ERCC3,NFKB1,ZFAND2B,RNF115,SOCS2,ARGLU1,GLUL,PSME1,RNASEH2C,MAP1B,HSD17B10,PNMA2,ZNRF1,CCR1,HTR2A,YES1,DYNLL1,BTG3,DYRK1A,VIRMA,RSRC1,NUDT18,CCNF,UBE2I,CCT2,SUB1,CUL3,NIBAN2,RSPH1,CREB3,AR,GMPS,UFD1,YTHDF1,PIAS1,BAP1,STK26,EP300,UBAC2,CYP39A1,SSBP2,RBMS2,NUDT3 |
| 2.265e-02 | -3.79 | negative regulation of hemopoiesis | biological process | GO:1903707 | 117 | 45 | 18204 | 5365 |
TCTA,IRF1,IL4,MIR222,PIK3R1,RUNX1,SOCS5,MIR30B,MIR21,IFNA2,TRIB1,CARTPT,INHA,CTLA4,LILRB4,SNAI2,MIR221,IL2,RC3H2,FBXO7,IFNB1,TMEM176A,UBASH3B,TOB2,CBFB,BCL6,TMEM176B,FOXP3,LILRB1,C1QC,HMGB1,PRDX2,CCL3,CDK6,GPR137,TLR4,FBXW7,FCGR2B,FGL2,TLR3,ADIPOQ,TNFAIP6,CTNNB1,MYC,SFRP1 |
| 2.265e-02 | -3.79 | EFR3A (EFR3 homolog A) | protein interactions | 23167 | 107 | 40 | 19454 | 5460 |
AQP3,FGFR1,VPS4B,NUPR1,RND3,ISG20,ATG16L1,RND2,PPP2R1A,CDC42,KRAS,FLOT1,RHOU,TMEM185A,RHOB,ATG3,LAMTOR1,RHOG,NTRK3,RAB11A,RAB2A,LAMP2,DNAJC5,HDAC6,LAMP3,RHOJ,RHOH,ARF6,VIRMA,ESR2,CAV1,UBE2V2,DIRAS3,VPS72,CHRM4,HRAS,FBXO31,RAB35,RAC2,GJA1 |
| 2.265e-02 | -3.79 | TFAP2A (transcription factor AP-2 alpha) | protein interactions | 7020 | 107 | 40 | 19454 | 5460 |
OCRL,KCTD15,SH3BP4,NUP35,DEK,VEGFA,UBN1,CSNK2B,AP2M1,EED,RB1,UBE2I,BRCA1,SP1,NFKB1,MYC,WWP2,CSNK2A1,CTNNB1,BAG3,AR,STAU1,ASF1A,ADRB2,COIL,SSRP1,HIRA,XRCC5,EWSR1,EP300,PPARG,WWP1,RBPJ,TMOD1,GSTO2,MAX,TP53,SOX2,JUN,CFTR |
| 2.267e-02 | -3.79 | Activin_recp | pfam domains | PF01064 | 9 | 6 | 17795 | 5224 |
ACVR1B,ACVR1,BMPR2,BMPR1A,BMPR1B,ACVR1C |
| 2.267e-02 | -3.79 | KOW | pfam domains | PF00467 | 9 | 6 | 17795 | 5224 |
RPL26,RPL27,RPL26L1,RPS4X,SUPT5H,MRPL24 |
| 2.267e-02 | -3.79 | PAZ | pfam domains | PF02170 | 9 | 6 | 17795 | 5224 |
PIWIL3,PIWIL2,DICER1,PIWIL1,AGO1,PIWIL4 |
| 2.267e-02 | -3.79 | Glyco_transf_8 | pfam domains | PF01501 | 9 | 6 | 17795 | 5224 |
LARGE1,GLT8D1,XXYLT1,GXYLT2,GLT8D2,GXYLT1 |
| 2.280e-02 | -3.78 | positive regulation of type II interferon production | biological process | GO:0032729 | 76 | 31 | 18204 | 5365 |
IL1B,LILRB1,CEBPG,IL12A,CD14,HSPD1,PTPN22,IL18,SASH3,TLR9,TRIM27,TLR4,PYCARD,HRAS,PDE4B,CYRIB,IL2,CCR2,ISG15,TLR8,IL12B,TLR3,JAK2,TLR7,TNF,CD2,IL21,CLEC7A,IRF8,LTA,IL23A |
| 2.281e-02 | -3.78 | purine deoxyribonucleotide metabolic process | biological process | GO:0009151 | 16 | 9 | 18204 | 5365 |
DCK,SAMHD1,NUDT16,NUDT18,ADK,GUK1,NT5C2,PNP,AK5 |
| 2.281e-02 | -3.78 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | GO:0045869 | 16 | 9 | 18204 | 5365 |
APOBEC3D,MORC2,APOBEC3F,APOBEC3A,APOBEC3H,APOBEC3B,APOBEC3G,INPP5K,APOBEC3C |
| 2.281e-02 | -3.78 | positive regulation of nitric-oxide synthase biosynthetic process | biological process | GO:0051770 | 16 | 9 | 18204 | 5365 |
STAT1,AKAP12,TLR2,MAP2K3,IFNG,TLR4,MAP2K6,CCL2,JAK2 |
| 2.281e-02 | -3.78 | MyD88-dependent toll-like receptor signaling pathway | biological process | GO:0002755 | 16 | 9 | 18204 | 5365 |
TLR6,TLR9,IRAK4,TLR4,TIRAP,HSPD1,TRAF6,IKBKB,MYD88 |
| 2.281e-02 | -3.78 | regulation of receptor binding | biological process | GO:1900120 | 16 | 9 | 18204 | 5365 |
B2M,ADIPOQ,NOG,GREM2,PCSK9,IL10,HFE,MMP9,MIR148A |
| 2.281e-02 | -3.78 | positive regulation of cyclin-dependent protein kinase activity | biological process | GO:1904031 | 16 | 9 | 18204 | 5365 |
AKT1,PROX1,CCND3,RGCC,PSMD10,CCNY,CCND1,HSP90AB1,PSRC1 |
| 2.281e-02 | -3.78 | cardiac left ventricle morphogenesis | biological process | GO:0003214 | 16 | 9 | 18204 | 5365 |
NPY2R,SMAD4,RBPJ,EDNRA,NPY5R,GSK3A,CPE,TGFBR2,HEY2 |
| 2.281e-02 | -3.78 | negative regulation of glucose import | biological process | GO:0046325 | 16 | 9 | 18204 | 5365 |
GSK3A,PEA15,TNF,MIR107,GRB10,LEP,SELENOS,PID1,MIR143 |
| 2.281e-02 | -3.78 | regulation of ATP biosynthetic process | biological process | GO:2001169 | 16 | 9 | 18204 | 5365 |
TMSB4X,SPHK2,ENO1,MIR675,PPARA,PID1,IL4,DNAJC30,TAFAZZIN |
| 2.281e-02 | -3.78 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | GO:0000463 | 16 | 9 | 18204 | 5365 |
RPL7L1,RPF2,WDR12,RPL7,ZNHIT3,ZNHIT6,FTSJ3,RPL35,RBM34 |
| 2.281e-02 | -3.78 | insulin metabolic process | biological process | GO:1901142 | 16 | 9 | 18204 | 5365 |
FOSL2,YIPF5,PAX6,IDE,CPE,CTSD,SLC30A5,NLGN2,PCSK2 |
| 2.283e-02 | -3.78 | nucleotidyltransferase activity | molecular function | GO:0016779 | 142 | 54 | 18094 | 5411 |
POLR1H,POLR2B,TERT,POLR3H,PARP2,MB21D2,POLR2L,POLB,POLD4,CTU1,CHRAC1,FHIT,UGP2,GMPPB,POLR1D,NUDT5,TENT2,SELENOO,GDPGP1,POLE4,MED21,TENT5C,TENT4A,OAS1,POLR2C,TNKS2,GPHN,POLR1B,UAP1,PAPOLA,DKC1,TNKS,POLR2I,TERC,FPGT,CMAS,DNTT,POLR3B,PARP11,POLR2F,POLE3,MAB21L1,PCYT1B,KARS1,POLR3F,TENT5D,TAMM41,PAPSS2,PTGES3,THG1L,POLL,ART5,CGAS,PAPOLB |
| 2.285e-02 | -3.78 | signaling receptor binding | molecular function | GO:0005102 | 1493 | 481 | 18094 | 5411 |
TULP3,NSG1,TGFB2,VEGFA,ELAPOR2,KCNJ8,SOCS2,CCNB1,CNPY3,P2RY1,CNRIP1,OPHN1,HMGA1,IRAK4,MLN,CXCL8,NHERF1,DEFB1,HBEGF,TMBIM1,PIK3AP1,TLR5,TIAM1,PNOC,NR1H2,LGI1,GPRASP2,CDK5,CTNNB1,SNX17,THY1,IFNA2,IL1A,SMURF1,TRAF1,CCN3,FGF13,C1QL1,SST,JAK2,NETO2,PSMC5,TTR,HMGB1,CCL28,RIT2,OGN,IFNB1,CCL1,SPRED1,SMAD3,ICAM1,JAKMIP1,CD9,SIPA1L1,EPHA4,RLN2,RIC3,CXCL14,DPP4,TYROBP,FAM83B,EMP2,PIK3R2,TLR6,CSH1,CX3CL1,WIF1,RARRES2,YWHAH,ANGPTL2,INHA,TNFSF13,CLU,BTN2A2,TUBB4B,CYTL1,FGFR1,SFRP1,TUBB,PLSCR1,ADRB3,LAMB2,CCL19,NTF4,NXPH3,IL4,MTRNR2L7,CCL23,CNIH4,IFNK,REN,ADRB1,FEM1B,CD86,STOML2,AR,VEGFC,ICAM3,LY6H,IL13,FGF23,MTRNR2L3,TLR4,IGF1,REG1A,CER1,DEFB114,TOLLIP,SNX2,FGF10,CCL5,TMED1,APLN,GNRH2,CLSTN3,PPIA,CD81,ZDHHC17,AIP,GABARAPL1,LRRC4B,AMELX,FGF17,SDCBP,FGF12,JAML,CDC42EP2,UCN,CASK,TLR1,PRL,GPR17,SCG2,GRIA1,TLR9,IGSF11,SMARCD3,LY96,NPPC,FERMT2,MICB,KCTD10,TNFSF12,PRMT2,FLRT2,FBLN5,LGALS3,CYRIB,ARRDC3,LCN1,IGF1R,RNF126,SPG21,CCL25,S100A8,LRTM2,IL6ST,SMAD2,OSM,PTHLH,ANGPT1,PTPN11,OSGIN2,IL5,STAP1,GNAI3,TAFA1,DLK2,NPY,FCN2,PIK3CG,IL1RAP,CACNG3,RTP4,PROK1,TP53,PDYN,DDT,CLEC7A,PLG,TNF,FLOT1,FABP4,HFE,LHFPL4,GPNMB,SOCS5,ALCAM,STAT1,RER1,EFNB1,BOK,SEMA6C,NCSTN,CXCL3,LANCL1,HSP90AA1,SHC1,CD151,NETO1,LILRB1,LGALS8,PTPN1,IL10,ADIPOQ,CDC42,SRC,ANKRA2,SEMA4C,TGFB1I1,HCRT,STC1,SHC3,TRIM37,ITGB8,NLGN1,SQSTM1,FGF3,IL12A,GABARAPL2,AGR2,NCK1,PTGER1,RLN3,CXCL9,IZUMO1,ACTN4,CXCL10,JCHAIN,PYCARD,PRNP,PRKCA,GNAO1,RALA,CIB2,DVL2,TIRAP,SNX5,EMILIN1,IL7,ALKAL1,IKBKB,IL22,SIVA1,CCL11,IFNA10,TIMP1,CALR,CSNK2B,CCL4L1,TRAF2,WNT10B,KLRD1,ADORA1,CD36,COL3A1,GABARAP,LTA,MYD88,IL12B,MIF,WNT7A,EFNA5,PICK1,SPRED2,IL18BP,MSN,SPP1,RNF41,CD3G,CD226,FEM1A,BGLAP,RAB8B,AP2M1,USP15,DUSP3,CCL21,CD40LG,LRP6,HILPDA,SEMA7A,FGF22,RPGRIP1L,CMTM7,VIP,IFNA13,NPB,CRKL,PTPN4,PICALM,ITGA6,CXCL11,NF2,MPP1,GRB10,SLC6A3,EGFL8,TRAF3IP2,ENHO,CAV1,YES1,PLSCR4,CXCL13,PSEN1,TSNAX,CCL27,GNAZ,NDP,DLG4,MAVS,NLGN2,CNPY4,IL23A,TAPBP,MSTN,ITGAV,IFNG,ELMO2,ATP5F1B,CCL3,GH1,GNA14,ADM2,SYNDIG1,NPVF,GJA1,CDNF,CXCL12,AP2A1,UTS2,CD58,CX3CR1,HOMER3,MADCAM1,TESPA1,CUL3,TLR2,PHB1,PIK3R1,GNA11,TRPC1,FLRT3,XCL1,LEP,TNFSF10,CD2,IL21,EGFL7,VWF,CCL17,CDK5R1,IL15,PLXNC1,OPRK1,IL17F,SEMA3C,FKBP1B,GSTM2,FGF16,MBL2,FRS3,HSPA8,FAM3C,MCHR1,CKLF,EPO,CBL,GRAP,ARF4,GNAI2,TLR10,APBB3,SEMA5A,F11R,MSMP,PTPRZ1,PTN,MMP14,RGMA,ANXA7,ISG15,CXCL1,S100B,SNX1,IL6,IZUMO1R,WNT2,F7,DLG3,FGF1,IGFBP4,PACRG,F2,CPE,GNRH1,ICAM2,LMBRD1,SCYL2,IL18,ITGB5,CCR2,CCL18,TAC1,ARPP19,NPTN,DKK1,ATP5F1A,HYAL2,CFC1,YWHAG,MDM2,HCST,DERL1,TNFSF8,TNFSF15,TRIM24,VAV2,FASLG,CD80,HOMER1,LRRTM2,TCIM,STUB1,MOG,CCL20,LYNX1,PPY,LACRT,GPHA2,BEX3,GREM2,CCL24,GNAQ,CNTFR,IL2,IL34,NPW,NEO1,SYK,IL1B,CSF2,PCSK9,ESR2,CCL8,FGF7,LHB,RETN,ITGA2,LCP1,GHRL,HSP90B1,CCL2,GREM1,DLG1,HTR1A,TNFSF18,SEC14L1,TRAF6,SRI,GSK3A,SLC6A4,LTB,DKK3,EFNA3,ZBTB16,BMP1,CARTPT,TGFBR2,CD4,FKBP1A,TF,FGR,IL3,JAK1,TRAK2,PCNA,NCR3LG1,TGFB3,CTNND1 |
| 2.286e-02 | -3.78 | Herpes simplex infection | KEGG pathways | hsa05168 | 185 | 77 | 7161 | 2463 |
FASLG,PPP1CB,IKBKB,TRAF2,CREBBP,PTPN11,GTF2I,MAPK10,TAF10,IFNAR1,NFKBIB,TRAF1,SRSF2,IL12B,IFNGR1,JAK2,IRF9,SOCS3,OAS1,IL1B,IFNA13,SRSF7,SRSF4,TNF,CCL2,IRF7,TLR2,RNASEL,TAB2,CDK1,RIGI,TBK1,NOP53,IL15,EIF2S1,TICAM1,TAF5L,STAT1,TNFRSF14,JUN,JAK1,IFNA2,NECTIN2,PML,SRSF8,NFKBIA,IRF3,IL12A,LTA,EP300,EIF2AK2,TP53,HCFC2,IFNG,FOS,TLR3,MAVS,SRSF1,PPP1CC,IL6,TAB1,ALYREF,CSNK2B,TLR9,MYD88,HNRNPK,IFNB1,SKP1,FAS,IFNA10,NFKB1,CSNK2A1,IFIH1,TRAF6,STAT2,GTF2IRD1,CCL5 |
| 2.286e-02 | -3.78 | Herpes simplex infection | KEGG pathways | ko05168 | 185 | 77 | 7161 | 2463 |
TICAM1,EIF2S1,NOP53,TBK1,IL15,RIGI,CDK1,JUN,TNFRSF14,STAT1,TAF5L,CCL2,TNF,SRSF4,IL1B,IFNA13,SRSF7,RNASEL,TAB2,TLR2,IRF7,JAK2,OAS1,SOCS3,IRF9,TAF10,IFNAR1,PTPN11,CREBBP,TRAF2,MAPK10,GTF2I,FASLG,IKBKB,PPP1CB,IL12B,IFNGR1,NFKBIB,SRSF2,TRAF1,IFNA10,NFKB1,SKP1,FAS,HNRNPK,IFNB1,MYD88,CCL5,GTF2IRD1,STAT2,TRAF6,IFIH1,CSNK2A1,IL6,TLR9,CSNK2B,TAB1,ALYREF,HCFC2,IFNG,TP53,SRSF1,MAVS,TLR3,PPP1CC,FOS,PML,NECTIN2,IFNA2,JAK1,EP300,LTA,EIF2AK2,IL12A,NFKBIA,IRF3,SRSF8 |
| 2.288e-02 | -3.78 | regulation of TOR signaling | biological process | GO:0032006 | 147 | 55 | 18204 | 5365 |
MAPKAPK5,SAR1B,RRAGB,SLC38A9,LAMTOR2,STAMBPL1,RNF152,GSK3A,PIH1D1,SESN2,CASTOR2,YWHAZ,RHEB,PRKACB,TMEM127,KLHL22,LAMTOR1,ZMPSTE24,HDAC3,CUL3,UBE2D1,TBK1,CSNK1A1,UBE2N,F10,MTM1,FBXO9,CRYBA1,UBE3A,EP300,F7,RRAGA,UBE2W,YWHAG,PIK3CA,KICS2,SEC13,SESN3,FLCN,SRC,MIOS,SH3BP4,AKT1,AKT3,MINAR1,LAMTOR3,SYK,GPR137,C9orf72,STK11,RNF167,TNFAIP8L1,LEP,PIP4P1,DDIT4 |
| 2.291e-02 | -3.78 | DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3) | protein interactions | 8444 | 30 | 14 | 19454 | 5460 |
EIF3K,SF3B6,SMU1,PRNP,EIF2S1,GDPD3,EIF3E,SNRPB2,TRMT61A,FBXO25,GORASP2,TPM3,LACRT,HSPB1 |
| 2.291e-02 | -3.78 | SMTNL2 (smoothelin like 2) | protein interactions | 342527 | 30 | 14 | 19454 | 5460 |
YWHAH,YWHAG,CCNA2,SNAP29,CKS1B,NUP62,SFN,UPK1A,KRT7,APTX,YWHAB,YWHAZ,S100A8,EGFL8 |
| 2.291e-02 | -3.78 | GRIN3B (glutamate ionotropic receptor NMDA type subunit 3B) | protein interactions | 116444 | 30 | 14 | 19454 | 5460 |
ATF1,TPD52,TPD52L1,CGRRF1,GUCY1B1,DLG4,PTK7,ABCB9,HSPA5,EDEM2,TAX1BP1,SPCS1,DAPK3,SPPL3 |
| 2.291e-02 | -3.78 | MEAK7 (MTOR associated protein, eak-7 homolog) | protein interactions | 57707 | 30 | 14 | 19454 | 5460 |
IFI16,TAS2R7,TANK,RAB11A,DUSP22,TP53I3,HRAS,NFKBIA,CMTR1,TMEM185A,CERS2,SLC31A1,KRAS,PRNP |
| 2.291e-02 | -3.78 | EEPD1 (endonuclease/exonuclease/phosphatase family domain containing 1) | protein interactions | 80820 | 30 | 14 | 19454 | 5460 |
TMEM185A,DPM2,CERS2,HNRNPL,SPPL3,KRAS,NCSTN,CIAO1,ANKRD50,ISG20,RHOB,FEM1A,FYTTD1,MED21 |
| 2.291e-02 | -3.78 | FBXO46 (F-box protein 46) | protein interactions | 23403 | 30 | 14 | 19454 | 5460 |
DDX5,DHX9,SLC25A11,SKP1,ESR2,TCP1,RUVBL1,COPS5,DDX39A,MCM4,EMILIN1,TOP3B,RAF1,CAPZA2 |
| 2.291e-02 | -3.78 | TSEN54 (tRNA splicing endonuclease subunit 54) | protein interactions | 283989 | 30 | 14 | 19454 | 5460 |
RINT1,MCPH1,PRR3,CSNK2B,IRF4,CUL3,LMO2,MOV10,TSEN34,TRIM23,BRCA1,ZNRF1,CLP1,NCKIPSD |
| 2.291e-02 | -3.78 | CILP2 (cartilage intermediate layer protein 2) | protein interactions | 148113 | 30 | 14 | 19454 | 5460 |
MATN4,RIGI,FBLN5,NCR3,CCL4L1,FEM1A,SFTPC,TMEM106A,DDX39A,CCL3,KLHL22,PI15,NOTCH2,CFC1 |
| 2.291e-02 | -3.78 | MINDY2 (MINDY lysine 48 deubiquitinase 2) | protein interactions | 54629 | 30 | 14 | 19454 | 5460 |
MBLAC2,ALG11,RETSAT,KCNJ11,NCR3LG1,PTRH2,PPM1B,SLC2A8,GNPAT,XXYLT1,CTU1,HSDL1,DNAJC1,GPX1 |
| 2.291e-02 | -3.78 | GAS2L3 (growth arrest specific 2 like 3) | protein interactions | 283431 | 30 | 14 | 19454 | 5460 |
CDK1,CAPZA2,CAMSAP2,TRIM36,H1-1,BIRC5,RAF1,PPP1CB,BTF3,SOX2,PRNP,ESR2,ABCE1,TSR2 |
| 2.291e-02 | -3.78 | CLEC10A (C-type lectin domain containing 10A) | protein interactions | 10462 | 30 | 14 | 19454 | 5460 |
SLC38A7,BET1,TSPO,CFTR,GNG10,FAM241A,SEC22A,FXYD6,SMCO4,ZDHHC15,UNC50,ADIPOQ,FMO3,TNF |
| 2.295e-02 | -3.77 | tRNA processing | biological process | GO:0008033 | 135 | 51 | 18204 | 5365 |
TRMT1L,GRSF1,DTWD1,KARS1,DDX1,POP7,HSD17B10,TRMT13,POP5,FTSJ1,RPP21,ADAT1,TRMT112,TRMT5,TYW5,RTRAF,QNG1,GON7,RPP25L,DPH3,CLP1,OSGEP,TSEN54,DUS4L,OSGEPL1,TYW3,RTCB,THUMPD1,METTL6,TRMT11,ELP3,LSM6,THG1L,TRMO,URM1,WDR6,TSEN34,CTU1,RPP14,DTWD2,KTI12,GTDC1,QTRT2,TRMT6,METTL2A,RPP25,TRUB1,TRMT61A,TRMT10B,ELP6,FAM98A |
| 2.295e-02 | -3.77 | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | Pathway Interaction DB | nfat_tfpathway | 48 | 24 | 2226 | 782 |
FASLG,IL2,CTLA4,FOXP3,PTPN1,CXCL8,JUNB,TNF,EGR2,FOS,PPARG,JUN,IFNG,CDK4,IL2RA,IL4,CD40LG,PRKCQ,IRF4,EGR1,IL3,RNF128,IL5,CSF2 |
| 2.296e-02 | -3.77 | COG3 (component of oligomeric golgi complex 3) | protein interactions | 83548 | 104 | 39 | 19454 | 5460 |
SNRK,CD40,RAB1A,RAB5A,RAB30,NPTN,KRAS,CMAS,ATP6V1G1,ZDHHC17,COMMD8,SEC22B,FAM234A,PTAR1,COMTD1,SPG21,PPP2R1A,ACTR1A,KRT7,PSMA6,CHRM4,SCN2B,COQ8A,CINP,CD274,HNRNPL,ARF6,RAB1B,COG1,CAV1,MYL12A,ILVBL,GPR17,OPRM1,P2RY10,AGR2,SLC35A1,CDC73,TESK1 |
| 2.296e-02 | -3.77 | FAM50A (family with sequence similarity 50 member A) | protein interactions | 9130 | 104 | 39 | 19454 | 5460 |
CD2BP2,SPG21,RAF1,ATP5PB,TP53,TAF2,LMNA,RPA2,CBX3,HSPA8,EWSR1,MRPS11,ARPC2,RPA3,RPL31,NCDN,PML,FAM50B,RIGI,H3C1,CTNNBL1,TRA2B,KRAS,KDM1A,STAU1,RNF40,MOV10,CABCOCO1,PRPF19,ERCC3,MED4,SKIC8,DDX23,LMNB1,ZNF330,ZBTB2,APEX1,COG1,TUBB |
| 2.296e-02 | -3.77 | KLHL12 (kelch like family member 12) | protein interactions | 59349 | 104 | 39 | 19454 | 5460 |
ESR2,DCUN1D1,CAND1,MPP1,SYNE4,RPP25L,SEC23A,UBE2I,INMT,PHB1,PEA15,MAPRE1,RIT1,DROSHA,COPS5,NTAQ1,TBC1D10C,SEC13,NDC80,CUL3,VTA1,SKP1,BCL6,FGD2,NEDD8,KLHL28,DVL2,KLHL24,UBE2M,KLHL26,KLHL12,EZH2,SDCBP,NUDCD3,MRPL10,RAF1,KLHL3,SNX20,PRR13 |
| 2.296e-02 | -3.77 | INTS12 (integrator complex subunit 12) | protein interactions | 57117 | 104 | 39 | 19454 | 5460 |
PDCD4,CALU,TAS2R7,GPR17,CSNK2A1,YWHAH,TYW3,AR,POLR2I,TOP1,APLNR,ILVBL,POLR2B,ESR2,SLAIN2,JUNB,SSR2,PPP2CB,ZNF174,ST6GAL1,INTS10,POLR2F,RPA2,METTL14,GTF2IRD1,POLR2C,COMTD1,SUPT5H,PPP2R1A,MGARP,G3BP1,SEM1,PLPP6,SSRP1,CXCR4,LIN7C,RPA3,HAPSTR1,ELOF1 |
| 2.296e-02 | -3.77 | MSI1 (musashi RNA binding protein 1) | protein interactions | 4440 | 104 | 39 | 19454 | 5460 |
MRPL51,MIR20A,AQP3,RBMS2,MRPL12,STRBP,MIR34B,RAF1,RBFOX2,MEPCE,MIRLET7C,HNRNPF,HSCB,MRPL17,HNRNPH2,MIRLET7I,MIR34C,AKAP1,BAP1,NGRN,MIR221,MRPL18,RC3H2,SNRNP70,MIR98,MIR29C,MRPL9,DDRGK1,CUL3,RBFOX3,DUOXA2,MIRLET7D,EGLN3,FZR1,MIRLET7G,TRIM24,PNMA1,MRPL53,MIR7-2 |
| 2.296e-02 | -3.77 | SLC25A22 (solute carrier family 25 member 22) | protein interactions | 79751 | 104 | 39 | 19454 | 5460 |
FAF2,MAP1LC3B,TUBA1A,CDK7,TOP3B,RAF1,B3GNT2,TFRC,RNF113A,PML,TMEM263,RAB29,MDC1,DNLZ,NF2,DEPDC1B,CASP4,MYC,MICB,CUL3,KRBOX4,ICAM1,NTRK3,UBE2H,ILK,FGR,IKBKB,ATP1A3,SLC1A1,CCNF,SDHB,LMBR1L,ELK1,TMPO,EGLN3,CDK9,VIRMA,MAD2L2,ESR2 |
| 2.304e-02 | -3.77 | glutathione redox reactions I | BIOCYC pathways | HUMAN_PWY-4081 | 6 | 5 | 902 | 319 |
GPX7,GPX2,GPX3,GPX4,GPX1 |
| 2.304e-02 | -3.77 | Biological oxidations | REACTOME pathways | R-HSA-211859 | 222 | 84 | 10285 | 3229 |
UGP2,UGT2A3,CYP39A1,GSTK1,CNDP2,FMO2,CYP2D6,MTARC2,ADH1A,SULT1A3,CYP3A43,CYP2C8,GSTO1,CYP4F22,MGST2,GLYATL3,GSTM2,UGT1A1,GGCT,CYP7A1,GSTA2,HPGDS,CYP27A1,CYP11B1,CYP21A2,GSTT2B,SLC35D1,EPHX1,CYP4F12,FMO3,GSTM5,ADH1B,ABHD14B,GLYAT,POR,CYB5B,COMT,DPEP1,CYP27B1,PTGES3,CYP17A1,CBR3,GSTA4,CYP2R1,CYP11B2,AKR7A2,GGT7,CHAC2,MAT2A,DPEP3,GCLC,FMO1,SULT1B1,CYP26A1,ABHD10,GSTM4,MAT2B,UGDH,CYP2F1,ACSS2,CYP1B1,CMBL,CYB5R3,CYP4F8,GSTO2,GSTP1,GSTA1,HSP90AB1,CYP1A1,TRMT112,MGST3,PAOX,PAPSS2,CYP2C9,GSTT1,GSTM3,AIP,CYP4V2,SLC35B3,CYP2C18,NAT2,CYP3A5,AKR1A1,ESD |
| 2.304e-02 | -3.77 | WDR33 (WD repeat domain 33) | protein interactions | 55339 | 132 | 48 | 19454 | 5460 |
TIAM1,SNRNP70,MED4,WWP2,HNRNPA1,TRA2A,TOP1,NUP35,CDC5L,ZHX1,CDK6,HDAC11,RAF1,SUPT5H,CDK4,TP53,ISG15,ZBTB16,MRPS17,AHCYL1,MDC1,SRSF7,CCT2,MYO6,UBE2H,PAPOLA,AR,CPSF2,ZNF622,MED17,ESR2,CPSF1,GSK3A,RPA2,ATG16L1,CPSF4,MIR34B,CAPN1,RBMS2,B9D2,UFL1,EEF1G,AIF1,SAP18,WASF3,SNRPA,RPA3,P4HA2 |
| 2.304e-02 | -3.77 | TRAPPC5 (trafficking protein particle complex subunit 5) | protein interactions | 126003 | 132 | 48 | 19454 | 5460 |
HMG20A,HSP90AB1,POLE3,TRAPPC6B,RAB1B,TRAPPC3,TRAPPC10,EED,TRAPPC4,POU5F1,TRAPPC2L,ATG7,FAM174A,RAB5C,ATG9A,UBXN6,RIGI,KRAS,ARL5B,IGF1R,SLC39A3,SLC39A7,RAB1A,TRAPPC1,TRAPPC13,TRAPPC3L,AQP3,EZH2,DIPK1A,B3GNT2,B4GALT3,B4GALT1,S100A6,OPTN,RIT1,IGF2BP1,TRAPPC14,RAB2A,EP300,RPA3,TRAPPC6A,UBE2M,CTBP1,RPA2,KLRD1,NPY2R,CNPY3,FUT8 |
| 2.307e-02 | -3.77 | negative regulation of mitochondrial membrane permeability | biological process | GO:0035795 | 21 | 11 | 18204 | 5365 |
ACAA2,SLC25A5,BOK,SLC35F6,SLC25A31,SLC25A4,TMEM14A,GCLC,MIR17,IER3,BAK1 |
| 2.307e-02 | -3.77 | positive regulation of natural killer cell activation | biological process | GO:0032816 | 21 | 11 | 18204 | 5365 |
MIR130A,IL15RA,IL23A,BLOC1S3,TOX,JAK2,IL18,TYROBP,IL15,IL12B,IL12A |
| 2.307e-02 | -3.77 | cellular response to growth hormone stimulus | biological process | GO:0071378 | 21 | 11 | 18204 | 5365 |
GH1,STAT6,SHOC2,SOCS2,STAT5A,PIK3R1,JAK2,CSH1,GHR,PTPN1,JAK1 |
| 2.307e-02 | -3.77 | regulation of cell growth involved in cardiac muscle cell development | biological process | GO:0061050 | 21 | 11 | 18204 | 5365 |
G6PD,PPARA,CAV3,RGS2,PARP2,PI16,MIR208A,FOXP1,TOMM70,IGF1,GSK3A |
| 2.307e-02 | -3.77 | negative regulation of tissue remodeling | biological process | GO:0034104 | 21 | 11 | 18204 | 5365 |
CD38,CST3,TNFAIP3,CSK,SFRP1,PPARG,IL6,GPR137,CARTPT,UBASH3B,GREM1 |
| 2.307e-02 | -3.77 | Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate | KEGG pathways | M00010 | 8 | 6 | 7161 | 2463 |
IDH3B,IDH1,IDH2,ACO1,ACO2,IDH3A |
| 2.307e-02 | -3.77 | Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate | KEGG pathways | hsa_M00010 | 8 | 6 | 7161 | 2463 |
ACO2,IDH1,IDH3A,ACO1,IDH2,IDH3B |
| 2.307e-02 | -3.77 | TREX complex | KEGG pathways | hsa_M00406 | 8 | 6 | 7161 | 2463 |
DDX39B,THOC2,THOC6,ALYREF,THOC3,THOC1 |
| 2.307e-02 | -3.77 | TREX complex | KEGG pathways | M00406 | 8 | 6 | 7161 | 2463 |
THOC6,THOC2,DDX39B,ALYREF,THOC3,THOC1 |
| 2.307e-02 | -3.77 | TGF-beta signaling | KEGG pathways | hsa_M00680 | 8 | 6 | 7161 | 2463 |
SMAD4,TGFB3,TGFB2,TGFBR2,SMAD3,SMAD2 |
| 2.307e-02 | -3.77 | TGF-beta signaling | KEGG pathways | M00680 | 8 | 6 | 7161 | 2463 |
TGFB3,TGFB2,SMAD4,TGFBR2,SMAD3,SMAD2 |
| 2.312e-02 | -3.77 | tripeptide transmembrane transport | biological process | GO:0035443 | 9 | 6 | 18204 | 5365 |
SLC15A1,SLC25A39,SLC7A11,SLC15A2,ABCC5,GJA1 |
| 2.312e-02 | -3.77 | phospholipase C-activating dopamine receptor signaling pathway | biological process | GO:0060158 | 9 | 6 | 18204 | 5365 |
DRD3,GNA11,GNAQ,DRD1,GNA14,NHERF1 |
| 2.312e-02 | -3.77 | galactolipid metabolic process | biological process | GO:0019374 | 9 | 6 | 18204 | 5365 |
GAL3ST1,GALC,B3GALT2,B3GALT1,FA2H,B4GALT3 |
| 2.312e-02 | -3.77 | daunorubicin metabolic process | biological process | GO:0044597 | 9 | 6 | 18204 | 5365 |
AKR1C2,AKR1B1,AKR1A1,CBR4,AKR1C1,AKR7A2 |
| 2.312e-02 | -3.77 | response to vitamin E | biological process | GO:0033197 | 9 | 6 | 18204 | 5365 |
IGF1R,FKBP1B,BECN1,GPX1,LEP,SRSF2 |
| 2.312e-02 | -3.77 | positive regulation of granulocyte differentiation | biological process | GO:0030854 | 9 | 6 | 18204 | 5365 |
HCLS1,RUNX1,TESC,IL5,HAX1,TRIB1 |
| 2.312e-02 | -3.77 | vesicle fusion with Golgi apparatus | biological process | GO:0048280 | 9 | 6 | 18204 | 5365 |
YIPF5,SEC22B,STX5,VTI1B,BET1,YIPF4 |
| 2.312e-02 | -3.77 | regulation of branching involved in salivary gland morphogenesis | biological process | GO:0060693 | 9 | 6 | 18204 | 5365 |
TNF,FGF10,FGFR1,NTN4,FGF7,SNAI2 |
| 2.312e-02 | -3.77 | regulation of endothelial cell chemotaxis to fibroblast growth factor | biological process | GO:2000544 | 9 | 6 | 18204 | 5365 |
MIR149,FGF16,MIR424,FGF1,CXCL13,MIR16-1 |
| 2.312e-02 | -3.77 | positive regulation of metallopeptidase activity | biological process | GO:1905050 | 9 | 6 | 18204 | 5365 |
CLDN4,MIR21,MIR17,DDRGK1,CLDN3,MIR205 |
| 2.312e-02 | -3.77 | protein hexamerization | biological process | GO:0034214 | 9 | 6 | 18204 | 5365 |
LRRC8C,MAT2A,TWNK,LRRC8D,LRRC8A,UGDH |
| 2.312e-02 | -3.77 | positive regulation of T-helper 2 cell cytokine production | biological process | GO:2000553 | 9 | 6 | 18204 | 5365 |
CD81,RSAD2,IL6,XCL1,IL4,NLRP3 |
| 2.312e-02 | -3.77 | negative regulation of dendritic cell apoptotic process | biological process | GO:2000669 | 9 | 6 | 18204 | 5365 |
CCR7,CCL21,CCL19,BCL2L1,LILRB1,CXCL12 |
| 2.312e-02 | -3.77 | negative regulation of retrograde protein transport, ER to cytosol | biological process | GO:1904153 | 9 | 6 | 18204 | 5365 |
ERLEC1,OS9,UBAC2,DERL2,UBE2G2,SVIP |
| 2.312e-02 | -3.77 | positive regulation of cardiac muscle contraction | biological process | GO:0060452 | 9 | 6 | 18204 | 5365 |
MIR1-1,RGS2,HSP90AA1,CHGA,ADRA1A,UCN |
| 2.312e-02 | -3.77 | transcription elongation-coupled chromatin remodeling | biological process | GO:0140673 | 9 | 6 | 18204 | 5365 |
EPOP,SUPT5H,CDK9,SART3,SUPT4H1,USP15 |
| 2.312e-02 | -3.77 | behavioral response to ethanol | biological process | GO:0048149 | 9 | 6 | 18204 | 5365 |
DBH,CRHR1,EPS8,USP46,OPRM1,CRHBP |
| 2.312e-02 | -3.77 | spermidine metabolic process | biological process | GO:0008216 | 9 | 6 | 18204 | 5365 |
HDAC6,DHPS,SAT2,PAOX,SRM,SAT1 |
| 2.313e-02 | -3.77 | ARHGAP25 (Rho GTPase activating protein 25) | protein interactions | 9938 | 47 | 20 | 19454 | 5460 |
TRIM27,GTF2H2,HACD3,WDCP,PPM1G,HERC3,MAT2B,PRDX4,LANCL1,PSMA1,CAMK2G,RBBP7,PPP2R1A,ATG7,XPO1,DSTYK,MAT2A,MTCH2,ACACA,WRAP53 |
| 2.313e-02 | -3.77 | RMDN1 (regulator of microtubule dynamics 1) | protein interactions | 51115 | 47 | 20 | 19454 | 5460 |
EZH2,RPA2,SHC1,TOP3B,CABCOCO1,PAQR3,CENPM,TP53,H2AX,ECHDC1,STAU1,NTMT1,WIF1,SAR1B,PARL,NIPA2,S100A6,RPA3,EED,HSPA8 |
| 2.313e-02 | -3.77 | FBXL6 (F-box and leucine rich repeat protein 6) | protein interactions | 26233 | 47 | 20 | 19454 | 5460 |
UBE2A,APEX1,SKP1,FTL,TFG,ETV6,HSPD1,TFPT,VDAC2,PNO1,RAB9B,PTEN,DHX9,HSP90AA1,NLRP3,RAF1,CDK4,TP53,ATG7,CCNA2 |
| 2.313e-02 | -3.77 | KIF3B (kinesin family member 3B) | protein interactions | 9371 | 47 | 20 | 19454 | 5460 |
RPAP2,STK4,LMO4,LMO2,MOV10,SAV1,KIF3C,DYRK2,SMAD4,RAB4A,PSMC5,POLR3H,IFT172,RAB5A,MAP3K11,RAD21,STK3,VIRMA,AKAP12,PRNP |
| 2.313e-02 | -3.77 | PTS (6-pyruvoyltetrahydropterin synthase) | protein interactions | 5805 | 47 | 20 | 19454 | 5460 |
ZMYM6,SYP,SDCBP,SMCHD1,UBE2M,ZFP1,UBE2H,DDIT4L,PTS,FNDC8,ASB1,NTAQ1,FXR2,UFL1,SMURF1,COIL,AHCYL1,SAR1B,VIRMA,AP2M1 |
| 2.313e-02 | -3.77 | GMEB2 (glucocorticoid modulatory element binding protein 2) | protein interactions | 26205 | 47 | 20 | 19454 | 5460 |
EWSR1,CDC7,UBE2I,ATXN1L,SDC4,ELK3,PML,APEX1,ZBTB2,CEP19,SNRNP40,KLF12,LMO3,CREBBP,LMO2,MOV10,ZMYND19,CUL3,SDC2,KLF3 |
| 2.315e-02 | -3.77 | mitochondrial intermembrane space | cellular component | GO:0005758 | 80 | 32 | 19108 | 5553 |
CLPB,TIMM23,REXO2,COX19,AGK,AK2,FKBP10,TIMM8A,FBXL4,TIMM8B,NME4,CHCHD2,PRELID1,SOD1,NDUFB7,AIFM1,CMC4,HAX1,UQCC2,TIMM10,FGR,STOML2,COA4,ALPL,ARL2BP,TIMM29,RNASET2,COX17,STAR,HTRA2,TIMM13,CHCHD4 |
| 2.321e-02 | -3.76 | CYTOCHROME_B5_1 | prosite domains | PS00191 | 5 | 4 | 12186 | 3388 |
CYB5R4,FA2H,CYB5B,CYB5A |
| 2.321e-02 | -3.76 | HIT_1 | prosite domains | PS00892 | 5 | 4 | 12186 | 3388 |
HINT2,APTX,HINT1,FHIT |
| 2.321e-02 | -3.76 | IDH_IMDH | prosite domains | PS00470 | 5 | 4 | 12186 | 3388 |
IDH1,IDH2,IDH3A,IDH3B |
| 2.321e-02 | -3.76 | regulation of heart contraction | biological process | GO:0008016 | 208 | 75 | 18204 | 5365 |
MDM2,TNF,CACNB2,STC1,TNNT2,SCN3B,TGFB2,MIR1-1,MEF2A,ATP1A1,SLC1A1,SCN1B,POPDC2,GNAO1,TACR3,TMIGD3,RANGRF,TMEM38B,KCNJ2,RGS2,APLN,TRPC1,ADORA1,SRC,ADRA1A,ADORA3,GSTM2,KCND2,ADRB1,HSP90AA1,HEY2,BVES,SNTA1,ASB3,PIK3CG,PDE4B,CAV1,CLIC2,MIR200C,ATP2B4,EDNRA,EHD3,KCNIP2,KCNJ8,GSK3A,CHGA,FKBP1B,UCN,CAV3,SRI,FGF13,SUMO1,MIR448,SCN2B,PLN,ZMPSTE24,ADM2,MIR208A,NOS1AP,GJA1,DMPK,GSTO1,MIR30E,KCND3,KCNJ3,JUP,ATP1B1,ATP1A3,TNNI3K,GJC1,DLG1,HBEGF,SLC8A1,DES,ATP1A2 |
| 2.326e-02 | -3.76 | DPP9 (dipeptidyl peptidase 9) | protein interactions | 91039 | 101 | 38 | 19454 | 5460 |
RPA2,RPRD1B,NEFL,PARD6A,SYK,TP53,FAXC,ELFN2,NEK2,HNRNPF,RPA3,NCDN,GRIA2,NUDT2,HSPA8,MRFAP1,LCP1,THG1L,NIF3L1,MYO6,DNAJC7,FAM163B,LRRC4,CIAO1,COPS5,ISCA2,ANKRD10,STAT2,HNRNPL,TOM1L1,ABHD12,SPRED2,HRAS,ZNF664,SURF2,FBXO32,ARHGAP25,POLR3H |
| 2.326e-02 | -3.76 | CORO1A (coronin 1A) | protein interactions | 11151 | 101 | 38 | 19454 | 5460 |
DNAJC1,TAB1,ACTB,TMCC2,ESR2,EEF1B2,SMAD3,UBE2G2,COX4I1,TRAF7,CORO1C,NELL2,IFT172,AGR2,BICD2,RASSF8,MAGOH,LMO2,FOXA3,INSYN1,DKK1,PRKACB,USP14,GPM6A,EEF1G,RIGI,CORO6,POC1B,FHL3,IFT57,SKA2,ACTR2,GIT2,KRT7,NEK2,MRPL12,STXBP1,TMEM205 |
| 2.326e-02 | -3.76 | HEATR6 (HEAT repeat containing 6) | protein interactions | 63897 | 101 | 38 | 19454 | 5460 |
SDC2,CTDSP1,VAPB,STK16,EIF4B,PRKAB1,HOXB1,KLRD1,MGARP,PPP1CB,NPTN,PDHB,CTSC,LTA,PPIH,LRRN4CL,PDCD1,SMAD4,TYROBP,FIS1,ICAM1,NTRK3,HAX1,FAM174A,CUL3,MCM3,GAS8,TSN,WDR44,RAMP3,HRAS,CD79B,SSR2,CCNF,COQ8A,AIFM1,RPS20,PTEN |
| 2.329e-02 | -3.76 | RNA methylation | biological process | GO:0001510 | 79 | 32 | 18204 | 5365 |
SNRPD1,EMG1,TRMT6,METTL2A,SNRPB,RAMAC,TYW3,RBM15B,METTL6,SNRPG,METTL15,TRMT61A,TRMT11,TRMT10B,TRMT1L,SNRPD2,FTSJ3,HSD17B10,MEPCE,HENMT1,TRMO,SNRPD3,TRMT13,BUD23,WDR6,TFB1M,SNRPE,FTSJ1,MRM2,METTL25B,TRMT112,TRMT5 |
| 2.331e-02 | -3.76 | SGNH hydrolase | gene3d domains | 3.40.50.1110 | 7 | 5 | 14470 | 4137 |
SIAE,IAH1,PAFAH1B3,PCED1B,PAFAH1B2 |
| 2.331e-02 | -3.76 | Longin domain | gene3d domains | 3.30.450.50 | 7 | 5 | 14470 | 4137 |
VAMP7,YKT6,SEC22C,SEC22A,SEC22B |
| 2.331e-02 | -3.76 | - | gene3d domains | 6.10.140.1230 | 7 | 5 | 14470 | 4137 |
CHMP2A,CHMP1B,CHMP1A,CHMP5,CHMP2B |
| 2.331e-02 | -3.76 | 14-3-3 domain | gene3d domains | 1.20.190.20 | 7 | 5 | 14470 | 4137 |
YWHAB,YWHAZ,YWHAH,SFN,YWHAG |
| 2.334e-02 | -3.76 | channel inhibitor activity | molecular function | GO:0016248 | 39 | 18 | 18094 | 5411 |
CFTR,PCSK9,PACSIN3,VAMP8,STX7,CAV3,LAMP2,SCN3B,LYNX1,VTI1B,STX1A,FKBP1B,CAV1,STX8,FKBP1A,KCNMB2,SCN1B,STOM |
| 2.334e-02 | -3.76 | transporter inhibitor activity | molecular function | GO:0141110 | 39 | 18 | 18094 | 5411 |
FKBP1A,KCNMB2,SCN1B,STOM,PCSK9,PACSIN3,CFTR,VAMP8,STX7,CAV3,LAMP2,SCN3B,STX1A,VTI1B,LYNX1,FKBP1B,CAV1,STX8 |
| 2.335e-02 | -3.76 | IL-5 Signaling Pathway | WikiPathways | WP127 | 40 | 21 | 5310 | 1910 |
JUN,KRAS,GSK3A,SPRED1,RAF1,MAP2K1,FOS,PIK3CG,AKT1,PIK3R2,JAK2,PTPN11,STAT1,SHC1,SYK,MYC,STAT5A,ELK1,PIK3R1,IL2,JAK1 |
| 2.335e-02 | -3.76 | regulation of macrophage migration | biological process | GO:1905521 | 45 | 20 | 18204 | 5365 |
MMP14,IL34,CX3CL1,RARRES2,MIR24-1,DDT,CCL3,MIF,CCL5,MMP28,CD200R1,CD81,MSTN,STAP1,CD200,CD9,CX3CR1,CCR2,EMILIN1,P2RY12 |
| 2.335e-02 | -3.76 | lymphocyte costimulation | biological process | GO:0031294 | 45 | 20 | 18204 | 5365 |
TNFRSF14,ICOS,CAV1,CCL21,PIK3CA,SRC,CD274,AKT1,DPP4,CSK,CD28,PTPN11,EFNB1,CCL19,CD80,PDCD1LG2,CD86,CD40LG,CD81,YES1 |
| 2.336e-02 | -3.76 | Ribosomal protein S18 | gene3d domains | 4.10.640.10 | 3 | 3 | 14470 | 4137 |
MRPS18B,MRPS18A,MRPS18C |
| 2.336e-02 | -3.76 | Aconitase, domain 3 | gene3d domains | 3.30.499.10 | 3 | 3 | 14470 | 4137 |
IREB2,ACO1,ACO2 |
| 2.336e-02 | -3.76 | Ribosomal protein L10e/L16 | gene3d domains | 3.90.1170.10 | 3 | 3 | 14470 | 4137 |
RPL10L,MRPL16,RPL10 |
| 2.336e-02 | -3.76 | Aconitase, domain 4 | gene3d domains | 3.20.19.10 | 3 | 3 | 14470 | 4137 |
IREB2,ACO2,ACO1 |
| 2.336e-02 | -3.76 | - | gene3d domains | 3.30.70.1730 | 3 | 3 | 14470 | 4137 |
MRPL10,MRTO4,RPLP0 |
| 2.336e-02 | -3.76 | Single Helix bin | gene3d domains | 1.20.5.580 | 3 | 3 | 14470 | 4137 |
CPLX2,CPLX1,CPLX3 |
| 2.336e-02 | -3.76 | Glycolipid transfer protein | gene3d domains | 1.10.3520.10 | 3 | 3 | 14470 | 4137 |
GLTP,PLEKHA8,CPTP |
| 2.336e-02 | -3.76 | Alba-like domain | gene3d domains | 3.30.110.20 | 3 | 3 | 14470 | 4137 |
POP7,RPP25,RPP25L |
| 2.336e-02 | -3.76 | Ribosomal protein S11 | gene3d domains | 3.30.420.80 | 3 | 3 | 14470 | 4137 |
RPS14,MRPS11,MRPL18 |
| 2.336e-02 | -3.76 | Superoxide dismutase, copper/zinc binding domain | gene3d domains | 2.60.40.200 | 3 | 3 | 14470 | 4137 |
SOD1,SOD3,CCS |
| 2.336e-02 | -3.76 | RNA polymerase alpha subunit dimerisation domain | gene3d domains | 3.90.1800.10 | 3 | 3 | 14470 | 4137 |
POLR2B,POLR3B,POLR1B |
| 2.336e-02 | -3.76 | - | gene3d domains | 3.90.1100.10 | 3 | 3 | 14470 | 4137 |
POLR3B,POLR2B,POLR1B |
| 2.336e-02 | -3.76 | - | gene3d domains | 3.40.630.60 | 3 | 3 | 14470 | 4137 |
OAZ1,OAZ2,OAZ3 |
| 2.336e-02 | -3.76 | DNA-directed RNA polymerase, subunit 2, domain 6 | gene3d domains | 2.40.270.10 | 3 | 3 | 14470 | 4137 |
POLR3B,POLR2B,POLR1B |
| 2.336e-02 | -3.76 | Probable brix-domain ribosomal biogenesis protein | gene3d domains | 3.40.50.10480 | 3 | 3 | 14470 | 4137 |
IMP4,BRIX1,RPF1 |
| 2.336e-02 | -3.76 | - | gene3d domains | 2.40.50.150 | 3 | 3 | 14470 | 4137 |
POLR1B,POLR2B,POLR3B |
| 2.336e-02 | -3.76 | Regulatory factor, effector binding domain | gene3d domains | 3.20.80.10 | 3 | 3 | 14470 | 4137 |
TEX264,HEBP1,HEBP2 |
| 2.340e-02 | -3.76 | TEPSIN (TEPSIN adaptor related protein complex 4 accessory protein) | protein interactions | 146705 | 170 | 60 | 19454 | 5460 |
GUCD1,NGB,MMACHC,GNG13,AP1M1,TAPBPL,TRIM11,UBE3A,OAZ3,UNC50,MRPS18B,TCEA2,SLC25A11,EIF1AD,CDC23,LSM3,XPO1,CSNK2A1,VPS26C,TRIM45,ACBD7,ZER1,TRAPPC6A,MED31,MFAP1,TBC1D13,PAX9,TRIM68,LMO3,SF3A1,HSPA5,ASB3,LYG2,UTP23,CCDC186,DERL1,TNFAIP1,STK26,SF3B1,HSPA8,BAP1,SLU7,ZNF343,RIT1,TRIM23,ATOSB,ISCA2,GPRASP3,HPCA,NTAQ1,HNRNPC,GRB10,MORF4L1,RPL10,MAT2B,KCTD9,TRIM54,UBASH3B,PSMA6,CINP |
| 2.343e-02 | -3.75 | basal transcription machinery binding | molecular function | GO:0001098 | 61 | 26 | 18094 | 5411 |
SMYD3,RPRD1A,RPRD1B,RTRAF,ELOF1,AGO1,TAF7,GTF2E2,LLPH,GTF2B,RUVBL1,CDC73,RUVBL2,SUPT4H1,CCAR2,GTF2A1,NOP58,GTF2F1,AR,DHX9,ZNHIT6,DRAP1,GTF2A2,TP53,EDF1,ZNF326 |
| 2.343e-02 | -3.75 | basal RNA polymerase II transcription machinery binding | molecular function | GO:0001099 | 61 | 26 | 18094 | 5411 |
RUVBL1,CDC73,GTF2B,LLPH,GTF2E2,SUPT4H1,RUVBL2,RPRD1A,RPRD1B,SMYD3,AGO1,TAF7,RTRAF,ELOF1,DRAP1,ZNF326,EDF1,GTF2A2,TP53,GTF2A1,NOP58,CCAR2,ZNHIT6,AR,GTF2F1,DHX9 |
| 2.345e-02 | -3.75 | MBD2 (methyl-CpG binding domain protein 2) | protein interactions | 8932 | 151 | 54 | 19454 | 5460 |
KPNA1,PSMD7,IFI16,DPY30,ZBTB2,HMG20A,SHPRH,BRMS1L,EED,MYBL2,GATAD1,H2AZ1,SIN3A,SFRP1,RBPJ,SMARCB1,MTA2,PSMC3,STMN2,EZH2,H2AX,SOX2,SAP30,HINFP,MTA3,RAF1,MRPL22,PHF1,VTA1,RAD21,H3C1,RBBP7,CDK2AP2,HAPSTR1,DHX9,SMARCE1,AR,CREBBP,MYC,SMARCA5,HNRNPC,ACTB,LAMTOR3,RBBP4,TRIM27,PSMC5,PRMT5,PHF12,RALYL,WDR77,ACTL6A,MBD3,KDM1A,RNF113A |
| 2.347e-02 | -3.75 | PNKP (polynucleotide kinase 3'-phosphatase) | protein interactions | 11284 | 129 | 47 | 19454 | 5460 |
SNX2,SLC25A12,CNTROB,FBXO32,ACTA2,RPRM,EED,H2AC4,POLB,BRD3,EMX2,GAS8,SUV39H1,ZBTB14,TRIM37,MSANTD4,TRIM26,SSRP1,TCOF1,BCKDK,PICK1,NUPR1,KLHL12,SYNGR3,RBPJ,SP4,PNMA5,THAP1,SMAD5,LIG3,IRF2,SYNGR1,SYP,GZMK,MGST2,CREBBP,TBC1D1,MCM3,NF2,KDM1A,XRCC5,RPA3,SQSTM1,HBB,RPA2,LMNA,PGRMC1 |
| 2.347e-02 | -3.75 | NAB2 (NGFI-A binding protein 2) | protein interactions | 4665 | 129 | 47 | 19454 | 5460 |
TMEM209,DGCR6L,POLD2,ARL15,LMNA,RFXANK,CD2AP,MAT2B,JAKMIP2,ZMAT2,CRYBB3,SCNM1,PHOSPHO2,EXOC8,CCHCR1,GCC1,TRIM23,RFC5,NTAQ1,ZMYND19,PIK3R3,MORF4L1,CUL3,EGR1,PHF1,ENKD1,PSMA1,NAB1,SEPTIN7,TCEA2,RINT1,EGR2,TRAF2,SPG21,G6PD,TRIM35,DNAJB9,EEF1AKMT3,CDC23,NAB2,EIF5A2,DRG2,HSPB8,GSTM3,MDFI,UBXN6,USP2 |
| 2.347e-02 | -3.75 | SRSF12 (serine and arginine rich splicing factor 12) | protein interactions | 135295 | 129 | 47 | 19454 | 5460 |
TBC1D25,FAM110B,SMARCA5,DEPDC1B,RPL26,MAP3K21,SRPK2,SH3BP4,RPS3,RPS9,RBMX2,LARP4B,AGAP1,SIPA1L1,EIF5B,UTP23,RTKN,CLK1,FAM53C,TIAM1,SNRNP70,YWHAB,MAGOH,CAMSAP2,NOL12,EDC3,TRA2A,YWHAH,YWHAG,RPL7,KCTD3,RPS10,ZBTB2,SRSF10,KRR1,SRSF1,EIF4E2,CDK6,PRR3,LLPH,HBP1,KIF1C,NUP42,H1-6,SRSF4,SNIP1,TESK2 |
| 2.349e-02 | -3.75 | - | gene3d domains | 2.60.120.40 | 52 | 22 | 14470 | 4137 |
CBLN4,TNFSF10,TNF,LTB,C1QL2,TNFSF8,TNFSF12,TNFSF15,CD40LG,LTA,CBLN2,TNFSF13,CBLN1,TNFSF18,ADIPOQ,C1QTNF1,C1QL3,CBLN3,C1QL1,FASLG,C1QC,EMILIN1 |
| 2.354e-02 | -3.75 | UBE4A (ubiquitination factor E4A) | protein interactions | 9354 | 98 | 37 | 19454 | 5460 |
MAVS,EFNB1,CBX7,SEMA4C,SMC4,UBE2D3,ST7,OTULINL,ACTR1A,H2AX,TP53,FAM234A,FAM3C,VAPB,RSAD2,SIGLECL1,SEC61B,PTPN1,KCNA2,VIRMA,ESR2,MDM2,PTP4A3,B4GALT3,DNAJC1,IP6K1,COPS5,LRRTM1,SELENOS,EDEM1,GPR17,KCNJ2,EPHA2,PTTG1,SMAD4,UBE2D1,ATP1B3 |
| 2.354e-02 | -3.75 | MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5) | protein interactions | 11183 | 98 | 37 | 19454 | 5460 |
NTRK3,LYZ,LAMTOR1,RHOB,PPM1B,SHC1,SNRNP70,COPS5,YWHAG,DNAJC5,DPP4,MYC,RAB11A,MAD2L1,DIRAS3,SMURF1,CACYBP,CAV1,PRDX2,TXN,ARF6,GJA1,TRAF7,RAB35,RPL32,CTTN,CRKL,AKR1A1,RPA2,TP53I3,FGFR1,TRAF2,TANK,KRAS,RABGGTB,RPA3,EIF1AD |
| 2.354e-02 | -3.75 | CCDC93 (coiled-coil domain containing 93) | protein interactions | 54520 | 98 | 37 | 19454 | 5460 |
COMMD3,JUN,COMMD8,MAX,NUP62,PSMC3,GIT2,GOLGA5,EZH2,STMN2,COMMD2,MNS1,CNKSR3,TFPT,LTBR,PACSIN3,RIGI,OIP5,KDM1A,EXOC1,H2BC9,COMMD5,ATG7,INSYN1,HNRNPC,MYC,CCHCR1,CCDC22,COMMD9,PHF21A,RPRD1A,TMEM248,NUF2,VIRMA,HMG20A,COMMD6,VPS26C |
| 2.354e-02 | -3.75 | RBMX2 (RNA binding motif protein X-linked 2) | protein interactions | 51634 | 98 | 37 | 19454 | 5460 |
RPL17,SRSF12,DGCR8,COMMD2,DHX9,SRSF8,THNSL1,SNIP1,RBM34,JPH4,TOP3B,RAF1,H1-5,RPS14,ATG16L1,SRPK2,ESR2,ZBTB2,RPL13A,COMMD6,NKAP,HNRNPL,FZR1,FGFBP1,CSNK2B,PRKRA,LRRC1,RPL32,SRSF1,RPL8,CCNF,H1-1,DDX23,DCAF5,DDRGK1,ZNF668,RPL7A |
| 2.357e-02 | -3.75 | Actb (actin, beta) | protein interactions | 11461 | 186 | 65 | 19454 | 5460 |
FLOT1,CAPZA1,GTF3C3,RUVBL1,CYBRD1,MYO1B,RUVBL2,CPNE2,CCT8,PALM2AKAP2,GNA11,RAB1A,PPP1R12A,ACTR2,ARPC3,CAPZA2,PLS3,ACTN4,TCP1,FCHO2,SPTAN1,KCTD10,PPP1R18,CPNE1,TES,STAMBPL1,TPM3,RAB5C,STOML2,UNC45A,SRI,SNX33,ARPC2,SPECC1L,CSNK1G3,TRMT112,TMOD1,PICALM,STOM,DCTN4,SIPA1L1,CDC42,SPTBN1,GNAI2,RPL22,CHCHD3,RALA,PSMD4,TMOD3,RAB14,DAPK3,PTEN,AP2M1,RRAS2,EFHD2,CTTN,CCNF,AP2A1,NCKIPSD,ABCG2,MYO6,ARHGAP21,CFL1,CAP2,MAT2A |
| 2.358e-02 | -3.75 | SMAD binding | molecular function | GO:0046332 | 78 | 32 | 18094 | 5411 |
LDLRAD4,RGCC,PML,FKBP1A,FOS,SMAD3,TGFBR2,CITED1,COL3A1,PPARG,USP15,SMAD2,BMPR1A,BMPR1B,TGFB1I1,JUN,COL1A2,ACVR1,MEF2A,PAX6,EID2,DROSHA,SMAD4,SMURF1,DDX5,STUB1,SMAD5,ACVR1B,CTNNB1,FERMT2,SMAD9,SMAD1 |
| 2.358e-02 | -3.75 | locomotion | biological process | GO:0040011 | 367 | 126 | 18204 | 5365 |
CXCL3,PSEN1,HBEGF,PTN,SEMA4C,FZD4,CXCL13,JAML,FLRT2,CCL1,RHOG,GPNMB,PRKCQ,LECT2,PLGRKT,GAB1,EFNA5,SEMA7A,VEGFA,CCL27,TPBG,SRP54,LGALS3,VEGFC,CXCL14,PDE4B,PIK3CG,CCL8,CCL11,MACO1,PPIB,ANGPT1,SLC25A46,SCG2,RAC2,MIF,CCL3,ACKR3,ITGAV,MSMP,PPIA,SEMA6C,IL6,CCL17,SCN1B,FCER1G,CXCL8,CCL5,LPAR1,GPR37,CXCL9,NINJ1,CRKL,ADGRE2,RAB13,ATP1A2,SFTPD,CCL19,CCR2,LRTM2,DPP4,SLC12A2,KIT,FLRT3,RARRES2,CCL25,CCR5,CCL21,CKLF,MET,RPL13A,NEFL,CXCR3,DEFB114,CCL4L1,MAP2K1,CCR1,CHGA,CCL18,L1CAM,NRP1,CCL28,CCL2,NPPC,PIP5K1A,CXCL10,SEMA3C,ELMO2,CCL20,CXCL1,CREB3,HRAS,CXCR4,S100A8,CCR7,FOLR2,SEMA5A,CCR6,CXCR1,CCL23,IL1B,SERPIND1,CXCL12,EPHA2,CXCR6,CCR4,CH25H,SYK,FGF7,HMGB1,CMTM7,RALA,CXCL11,CCL24,CX3CR1,CCN3,FGF10,DEFB1,XCL1,IL10,TGFB2,CX3CL1,CCR3,PLP2,DPEP1,EP300 |
| 2.370e-02 | -3.74 | BAZ2B (bromodomain adjacent to zinc finger domain 2B) | protein interactions | 29994 | 50 | 21 | 19454 | 5460 |
H2BC9,SOX2,TRAF2,CEP70,CSK,STAC3,TFIP11,TRIM23,CHMP4C,DCAF4,EED,CSNK2B,NLE1,COIL,CCT7,FXR2,INA,RBBP7,SNRNP40,ZBTB14,PRNP |
| 2.370e-02 | -3.74 | PCLAF (PCNA clamp associated factor) | protein interactions | 9768 | 50 | 21 | 19454 | 5460 |
BUD31,TAX1BP1,FZR1,KRAS,SQSTM1,DLAT,RNF113A,PCNA,ZC3H11A,BRCA1,HECTD1,IL1R2,TPT1,NDUFA2,CCND1,SPTBN1,ATG16L1,HSPA14,CDKN1A,NEK7,ING1 |
| 2.370e-02 | -3.74 | TRIM15 (tripartite motif containing 15) | protein interactions | 89870 | 50 | 21 | 19454 | 5460 |
AKT1,SYK,FAM151B,FAM161A,TRIM8,CFL1,GTF2E1,SHC1,PTTG1,GAB1,CTTN,UBE2N,MYBL2,CDK6,MSN,ACTB,TRIM15,PRNP,ROCK1,FERMT2,SRC |
| 2.370e-02 | -3.74 | BUD23 (BUD23 rRNA methyltransferase and ribosome maturation factor) | protein interactions | 114049 | 50 | 21 | 19454 | 5460 |
OAS1,SQSTM1,EP300,THOC2,RPA3,CCAR1,APEX1,FZR1,KRAS,KIF2A,ZMYM3,MYC,FEN1,RAF1,BUD23,CUL3,TRMT112,UBE2H,RIT1,RPA2,ATG3 |
| 2.370e-02 | -3.74 | ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13) | protein interactions | 54503 | 50 | 21 | 19454 | 5460 |
TACR3,RIGI,HNRNPL,CX3CL1,LPAR1,SYNGR1,VIPR1,STARD3NL,SPINT2,TSPAN18,SPRED2,S1PR4,TSPAN15,CD83,CTXN1,PLD3,GPR35,CCR6,DNAJC5,PLSCR4,GPR17 |
| 2.370e-02 | -3.74 | ADNP2 (ADNP homeobox 2) | protein interactions | 22850 | 50 | 21 | 19454 | 5460 |
MIS12,ZMYM2,MACROH2A1,MYEF2,LRIF1,MAD2L1,CBX5,VIRMA,BTG3,NCKAP1,FTL,PRNP,GDPGP1,SNRNP40,DSN1,MOV10,MYC,KPNA1,CBX3,CHAMP1,ADNP |
| 2.370e-02 | -3.74 | RCBTB2 (RCC1 and BTB domain containing protein 2) | protein interactions | 1102 | 50 | 21 | 19454 | 5460 |
STX11,COPS4,HDAC3,YES1,PIK3R2,RCBTB1,ZBTB18,MRPS11,UBE2I,RPS24,HELLS,NUFIP2,IGF2BP1,HSP90AA1,CBL,ANKRD49,UBE2E3,PDE4B,CUL3,MORF4L1,RBBP9 |
| 2.370e-02 | -3.74 | MCRIP2 (MAPK regulated corepressor interacting protein 2) | protein interactions | 84331 | 50 | 21 | 19454 | 5460 |
CASC3,IGF2BP1,IL17F,RC3H2,CPEB1,YTHDF2,TOP3B,MOV10,RAF1,PRRC2A,YTHDF1,RP2,EEF1G,STAU1,G3BP1,TRIM11,LSM12,PML,PABPC1,SMAP2,HRAS |
| 2.370e-02 | -3.74 | CKMT2 (creatine kinase, mitochondrial 2) | protein interactions | 1160 | 50 | 21 | 19454 | 5460 |
G3BP1,RPS16,HSCB,TMED9,PSMD4,HSPE1,RBM42,LRIF1,G3BP2,PSPC1,MAP1B,OLFML3,METAP2,CETN3,DNAJC2,DRG1,SRP72,AP5M1,ABHD6,H2AX,IKZF5 |
| 2.371e-02 | -3.74 | central_nervous_system-frontal_lobe-glioma-astroblastoma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astroblastoma_Grade_III | 3 | 3 | 16828 | 4835 |
IDH2,IDH1,TP53 |
| 2.371e-02 | -3.74 | stomach-other-metaplasia | COSMIC cancer mutations | stomach-other-metaplasia | 3 | 3 | 16828 | 4835 |
PTEN,KRAS,TP53 |
| 2.371e-02 | -3.74 | ovary-germ_cell_tumour-embryonal_carcinoma | COSMIC cancer mutations | ovary-germ_cell_tumour-embryonal_carcinoma | 3 | 3 | 16828 | 4835 |
KRAS,KIT,DICER1 |
| 2.371e-02 | -3.74 | bone-other-neoplasm | COSMIC cancer mutations | bone-other-neoplasm | 3 | 3 | 16828 | 4835 |
KRAS,CTNNB1,CALR |
| 2.371e-02 | -3.74 | central_nervous_system-parietal_lobe-glioma-gliosarcoma | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-gliosarcoma | 3 | 3 | 16828 | 4835 |
IDH1,PTEN,IDH2 |
| 2.371e-02 | -3.74 | skin-hand-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-hand-benign_melanocytic_nevus-blue | 3 | 3 | 16828 | 4835 |
GNA11,HRAS,GNAQ |
| 2.371e-02 | -3.74 | skin-forearm-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-forearm-benign_melanocytic_nevus-blue | 3 | 3 | 16828 | 4835 |
GNA11,HRAS,GNAQ |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 3 | 3 | 16828 | 4835 |
KIT,CTNNB1,KRAS |
| 2.371e-02 | -3.74 | biliary_tract-gallbladder-other-pancreaticobiliary_malunion | COSMIC cancer mutations | biliary_tract-gallbladder-other-pancreaticobiliary_malunion | 3 | 3 | 16828 | 4835 |
CTNNB1,KRAS,SMAD4 |
| 2.371e-02 | -3.74 | small_intestine-ileum-other-dysplasia | COSMIC cancer mutations | small_intestine-ileum-other-dysplasia | 3 | 3 | 16828 | 4835 |
KRAS,IDH1,IDH2 |
| 2.371e-02 | -3.74 | skin-abdomen-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-abdomen-benign_melanocytic_nevus-blue | 3 | 3 | 16828 | 4835 |
GNAQ,GNA11,HRAS |
| 2.371e-02 | -3.74 | bone-osteochondroma | COSMIC cancer mutations | bone-osteochondroma | 3 | 3 | 16828 | 4835 |
EWSR1,IDH1,IDH2 |
| 2.371e-02 | -3.74 | bone-femur-chondrosarcoma-conventional | COSMIC cancer mutations | bone-femur-chondrosarcoma-conventional | 3 | 3 | 16828 | 4835 |
HRAS,IDH2,IDH1 |
| 2.371e-02 | -3.74 | skin-foot-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-foot-benign_melanocytic_nevus-blue | 3 | 3 | 16828 | 4835 |
GNAQ,HRAS,GNA11 |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | 3 | 3 | 16828 | 4835 |
KRAS,CTNNB1,KIT |
| 2.371e-02 | -3.74 | osteoblastoma | COSMIC cancer mutations | osteoblastoma | 3 | 3 | 16828 | 4835 |
CDH11,EWSR1,MET |
| 2.371e-02 | -3.74 | skin-leg-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-leg-benign_melanocytic_nevus-blue | 3 | 3 | 16828 | 4835 |
GNA11,HRAS,GNAQ |
| 2.371e-02 | -3.74 | hypertrophic_scar | COSMIC cancer mutations | hypertrophic_scar | 3 | 3 | 16828 | 4835 |
CTNNB1,AKT1,ETV6 |
| 2.371e-02 | -3.74 | vulva-carcinoma | COSMIC cancer mutations | vulva-carcinoma | 3 | 3 | 16828 | 4835 |
TP53,CDKN2C,RUNX1 |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-other-lymphangioma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-other-lymphangioma | 3 | 3 | 16828 | 4835 |
PIK3CA,IDH1,IDH2 |
| 2.371e-02 | -3.74 | central_nervous_system-cerebellum-glioma-astrocytoma | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma | 3 | 3 | 16828 | 4835 |
TERT,ACVR1,TP53 |
| 2.371e-02 | -3.74 | bone-rib-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-rib-chondrosarcoma-dedifferentiated | 3 | 3 | 16828 | 4835 |
IDH2,IDH1,HRAS |
| 2.371e-02 | -3.74 | soft_tissue-fibrous_tissue_and_uncertain_origin-hypertrophic_scar | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-hypertrophic_scar | 3 | 3 | 16828 | 4835 |
CTNNB1,AKT1,ETV6 |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | 3 | 3 | 16828 | 4835 |
KIT,CTNNB1,KRAS |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-sinonasal_and_nasal_cavity-lymphoid_neoplasm-B_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-sinonasal_and_nasal_cavity-lymphoid_neoplasm-B_cell_lymphoma_unspecified | 3 | 3 | 16828 | 4835 |
KIT,CTNNB1,KRAS |
| 2.371e-02 | -3.74 | pancreaticobiliary_malunion | COSMIC cancer mutations | pancreaticobiliary_malunion | 3 | 3 | 16828 | 4835 |
KRAS,CTNNB1,SMAD4 |
| 2.371e-02 | -3.74 | salivary_gland-face-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-face-carcinoma-adenoid_cystic_carcinoma | 3 | 3 | 16828 | 4835 |
HRAS,KIT,KRAS |
| 2.371e-02 | -3.74 | salivary_gland-parotid-carcinoma-mammary_analogue_secretory_carcinoma_of_salivary_glands | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-mammary_analogue_secretory_carcinoma_of_salivary_glands | 3 | 3 | 16828 | 4835 |
ETV6,CTNNB1,TP53 |
| 2.371e-02 | -3.74 | biliary_tract-gallbladder-other-hyperplasia | COSMIC cancer mutations | biliary_tract-gallbladder-other-hyperplasia | 3 | 3 | 16828 | 4835 |
KRAS,CTNNB1,SMAD4 |
| 2.371e-02 | -3.74 | mammary_analogue_secretory_carcinoma_of_salivary_glands | COSMIC cancer mutations | mammary_analogue_secretory_carcinoma_of_salivary_glands | 3 | 3 | 16828 | 4835 |
TP53,CTNNB1,ETV6 |
| 2.371e-02 | -3.74 | bone-tibia-chondrosarcoma-conventional | COSMIC cancer mutations | bone-tibia-chondrosarcoma-conventional | 3 | 3 | 16828 | 4835 |
IDH2,IDH1,TP53 |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 3 | 3 | 16828 | 4835 |
KIT,CTNNB1,KRAS |
| 2.371e-02 | -3.74 | central_nervous_system-parietal_lobe-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-oligodendroglioma_Grade_II | 3 | 3 | 16828 | 4835 |
PTEN,IDH1,IDH2 |
| 2.371e-02 | -3.74 | osteochondroma | COSMIC cancer mutations | osteochondroma | 3 | 3 | 16828 | 4835 |
IDH1,EWSR1,IDH2 |
| 2.371e-02 | -3.74 | central_nervous_system-parietal_lobe-glioma-oligodendroglioma | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-oligodendroglioma | 3 | 3 | 16828 | 4835 |
TP53,IDH1,IDH2 |
| 2.371e-02 | -3.74 | bone-pelvis-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-pelvis-chondrosarcoma-dedifferentiated | 3 | 3 | 16828 | 4835 |
IDH1,IDH2,HRAS |
| 2.371e-02 | -3.74 | large_intestine-rectum-other-ulcerative_colitis | COSMIC cancer mutations | large_intestine-rectum-other-ulcerative_colitis | 3 | 3 | 16828 | 4835 |
SMAD4,KRAS,TP53 |
| 2.371e-02 | -3.74 | central_nervous_system-temporooccipital-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-temporooccipital-glioma-astrocytoma_Grade_IV | 3 | 3 | 16828 | 4835 |
TP53,IDH2,IDH1 |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-adrenal_gland-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-adrenal_gland-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 3 | 3 | 16828 | 4835 |
CTNNB1,KRAS,KIT |
| 2.371e-02 | -3.74 | oligoastrocytoma_Grade_IV | COSMIC cancer mutations | oligoastrocytoma_Grade_IV | 3 | 3 | 16828 | 4835 |
IDH2,PTEN,IDH1 |
| 2.371e-02 | -3.74 | skin-groin-benign_melanocytic_nevus | COSMIC cancer mutations | skin-groin-benign_melanocytic_nevus | 3 | 3 | 16828 | 4835 |
HRAS,GNA11,GNAQ |
| 2.371e-02 | -3.74 | skin-trunk-benign_melanocytic_nevus | COSMIC cancer mutations | skin-trunk-benign_melanocytic_nevus | 3 | 3 | 16828 | 4835 |
GNAQ,HRAS,GNA11 |
| 2.371e-02 | -3.74 | lymphangioma | COSMIC cancer mutations | lymphangioma | 3 | 3 | 16828 | 4835 |
PIK3CA,IDH1,IDH2 |
| 2.371e-02 | -3.74 | bone-tibia-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-tibia-chondrosarcoma-dedifferentiated | 3 | 3 | 16828 | 4835 |
HRAS,IDH1,IDH2 |
| 2.371e-02 | -3.74 | bone-other-osteoblastoma | COSMIC cancer mutations | bone-other-osteoblastoma | 3 | 3 | 16828 | 4835 |
CDH11,EWSR1,MET |
| 2.371e-02 | -3.74 | skin-back-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-blue | 3 | 3 | 16828 | 4835 |
HRAS,GNA11,GNAQ |
| 2.371e-02 | -3.74 | peritoneum-carcinoma | COSMIC cancer mutations | peritoneum-carcinoma | 3 | 3 | 16828 | 4835 |
PIK3CA,KRAS,PTEN |
| 2.371e-02 | -3.74 | skin-shoulder-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus-blue | 3 | 3 | 16828 | 4835 |
GNAQ,HRAS,GNA11 |
| 2.371e-02 | -3.74 | skin-ankle-benign_melanocytic_nevus | COSMIC cancer mutations | skin-ankle-benign_melanocytic_nevus | 3 | 3 | 16828 | 4835 |
HRAS,GNA11,GNAQ |
| 2.371e-02 | -3.74 | bone-pelvis-chondrosarcoma-conventional | COSMIC cancer mutations | bone-pelvis-chondrosarcoma-conventional | 3 | 3 | 16828 | 4835 |
IDH2,IDH1,HRAS |
| 2.371e-02 | -3.74 | bone-femur-osteosarcoma-chondroblastic | COSMIC cancer mutations | bone-femur-osteosarcoma-chondroblastic | 3 | 3 | 16828 | 4835 |
IDH1,IDH2,RB1 |
| 2.371e-02 | -3.74 | central_nervous_system-temporal_lobe-glioma-gliosarcoma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-gliosarcoma | 3 | 3 | 16828 | 4835 |
IDH1,IDH2,TP53 |
| 2.371e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-muscle-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-muscle-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 3 | 3 | 16828 | 4835 |
CTNNB1,KRAS,KIT |
| 2.371e-02 | -3.74 | CBX8 (chromobox 8) | protein interactions | 57332 | 244 | 83 | 19454 | 5460 |
H3C1,PCGF3,SCML1,ZBTB14,PCGF6,PPAN,PICK1,RING1,FHL3,TFCP2,CHAMP1,CBX3,PNMA2,H2BC1,SFTPC,ILF2,PHC1,H2AJ,RAF1,TRAF2,SPPL3,PLEKHF2,TOP1,ALYREF,KRR1,EED,H2AC4,NAB2,CMSS1,MDFI,MOV10,INO80E,CSNK2A1,GPRASP2,NFIL3,STAU1,EEF1G,FBXW7,SKP1,PHACTR1,JAKMIP1,NLE1,NBN,EXOSC4,YAF2,PCGF2,EP300,PSMB7,LSM2,TFIP11,E2F6,RPS14,H1-5,GTF3C4,ELP3,MB21D2,KCTD9,TRIM54,SNRNP40,TAX1BP1,SCML2,RPL22,APEX1,ESR2,RPL10,PNMA1,SESTD1,LIG3,ZNF330,TRIM27,CSNK2B,MACROH2A1,RPS12,RPS20,H1-10,TRIM23,TXNIP,FTSJ3,IGF2BP1,MYC,RPL7A,CEP70,TTC23 |
| 2.375e-02 | -3.74 | postsynaptic membrane | cellular component | GO:0045211 | 280 | 97 | 19108 | 5553 |
GRM1,CRKL,DLG1,GABRA2,SNTA1,GABRB2,ATAD1,GRIK1,CHRNA7,EPHA4,LIN7B,ATP6AP2,CTNNB1,GLRA1,SLC6A3,TRAPPC4,HTR2A,DLG4,CHRM4,CHRM1,DAG1,KCNB1,LRRC4,TMUB1,HSPA8,ADORA1,FLRT3,SIGMAR1,CHRM5,SSPN,ZC4H2,GPHN,CNTN2,KCTD16,PRRT1,KCNJ2,KCNH1,DNM2,P2RY1,LRRTM3,GABBR1,DRD1,LRFN3,SLITRK1,LRRC4B,GABRA1,PCDH17,KCND3,GABRB3,RNF10,ABHD17A,LRRTM1,GLRA2,LRRTM2,SLC6A1,LPAR1,GABRG2,DLG3,CHRM3,GRIA1,CACNG3,FXYD6,CHRNB2,SLC6A4,GRIA2,NLGN2,KCNMA1,CLSTN3,NLGN1,GRID1,PDLIM4,SLC6A11,PCDHB13,IGSF21,SLC6A6,KCNC1,ABHD6,PICALM,SYNDIG1,NETO1,KCNA3,HTR5A,TIAM1,LIN7C,CNTN1,LHFPL4,NRP1,CBLN1,SEMA4C,KCNA2,KCTD12,OPRK1,KCND2,NETO2,RGS7BP,NSG1,GLRB |
| 2.379e-02 | -3.74 | Desipramine Action Pathway | SMPDB pathways | SMP0000423 | 27 | 16 | 1369 | 531 |
SCN1B,CYP2D6,ADRA1A,HTR1A,DRD1,OPRM1,ATP1A3,ATP1B1,ATP1B3,ATP1A2,SLC6A4,SLC6A2,KCNIP2,SLC6A3,ATP1A1,KCND2 |
| 2.379e-02 | -3.74 | Nalbuphine Action Pathway | SMPDB pathways | SMP0000691 | 27 | 16 | 1369 | 531 |
KCND2,SLC6A3,ATP1A1,SLC6A2,OPRK1,KCNIP2,ATP1A2,SLC6A4,ATP1A3,ATP1B1,ATP1B3,OPRM1,SCN1B,HTR1A,DRD1,ADRA1A |
| 2.382e-02 | -3.74 | KIF21A (kinesin family member 21A) | protein interactions | 55605 | 95 | 36 | 19454 | 5460 |
CCT5,UBL4A,MAP1LC3B,ADNP,SRP72,CCT8,HADHA,HUWE1,SRSF2,COPS4,SRSF4,PFDN1,MYC,MOV10,NONO,NT5C2,PPFIBP1,ZNF668,ENDOD1,DCAF4,CCT2,PFDN2,CCNF,GTF2F2,GTF2F1,HP1BP3,GSK3A,VPS26C,DYNLL1,TCP1,TTC9C,CDC5L,ZBTB2,CCT7,CD99L2,VIRMA |
| 2.382e-02 | -3.74 | ZACN (zinc activated ion channel) | protein interactions | 353174 | 95 | 36 | 19454 | 5460 |
GJC1,TMEM219,DIPK1A,CYB5R1,DDX39A,TMX4,SLC12A2,TMEM39A,FAM8A1,C1QL1,GPAA1,SEC11A,ITGA2,TMX3,COA1,EMC1,RDH11,DAD1,EDEM1,GJB2,LRRC8C,FAM241A,SLC41A3,TMEM106C,FAM241B,C1GALT1C1,SCAMP2,PTPN1,AMIGO1,ADGRG1,GJA1,DIPK2A,LRRC8A,DNAJB9,ATP6AP2,SRC |
| 2.382e-02 | -3.74 | MYOF (myoferlin) | protein interactions | 26509 | 95 | 36 | 19454 | 5460 |
TES,RAC2,PTEN,VDAC2,VIRMA,MATR3,RHOJ,RHOH,CGAS,RAB5C,ATP1A1,RHOG,AGR2,RHOB,HSPA8,EMC2,RHOU,RPA3,RNF11,HSPA5,EMC1,TRIM37,VDAC1,STAU1,TGFBR2,CDC42,ISG15,RND2,ATG16L1,TOP3B,ILF2,MOB3C,NUPR1,EZH2,RPA2,CHMP4C |
| 2.382e-02 | -3.74 | MIS18A (MIS18 kinetochore protein A) | protein interactions | 54069 | 95 | 36 | 19454 | 5460 |
CETN2,CAV1,EGLN3,HOMER1,CYTH4,G0S2,ZNF655,SENP5,RMDN3,SYBU,TNFRSF1B,UBE2H,RIT1,BICD2,SNAP91,CAV3,NTAQ1,CUL3,MYC,FNDC11,STX11,OIP5,KRAS,ACTR1B,DCTN3,DCTN6,TEDC2,SCLT1,CCL19,STX17,DMAP1,DCTN4,THAP1,GTF2E2,ACTR1A,ATG16L1 |
| 2.383e-02 | -3.74 | Signaling by FGFR3 | REACTOME pathways | R-HSA-5654741 | 40 | 19 | 10285 | 3229 |
UBA52,RPS27A,UBB,PIK3CA,CBL,PPP2R1A,PPP2CB,GAB1,HRAS,FGF23,KRAS,PTPN11,FGF17,FGF1,FGF16,SHC1,FRS3,PIK3R1,SRC |
| 2.383e-02 | -3.74 | skin-arm-benign_melanocytic_nevus | COSMIC cancer mutations | skin-arm-benign_melanocytic_nevus | 7 | 5 | 16828 | 4835 |
GNAQ,KRAS,HRAS,GNA11,AKT1 |
| 2.383e-02 | -3.74 | central_nervous_system-temporal_lobe-other-ganglioglioma | COSMIC cancer mutations | central_nervous_system-temporal_lobe-other-ganglioglioma | 7 | 5 | 16828 | 4835 |
GNA11,KRAS,GNAQ,IDH2,IDH1 |
| 2.383e-02 | -3.74 | salivary_gland-lip-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-lip-carcinoma-adenoid_cystic_carcinoma | 7 | 5 | 16828 | 4835 |
HRAS,KIT,KRAS,PIK3CA,PTEN |
| 2.383e-02 | -3.74 | skin-adnexal_tumour-trichilemmoma | COSMIC cancer mutations | skin-adnexal_tumour-trichilemmoma | 7 | 5 | 16828 | 4835 |
PIK3CA,CTNNB1,KRAS,HRAS,PTEN |
| 2.383e-02 | -3.74 | pterygopalatine_fossa | COSMIC cancer mutations | pterygopalatine_fossa | 7 | 5 | 16828 | 4835 |
PTEN,PIK3CA,HRAS,KIT,KRAS |
| 2.383e-02 | -3.74 | endometrium-hyperplasia-atypical | COSMIC cancer mutations | endometrium-hyperplasia-atypical | 7 | 5 | 16828 | 4835 |
HRAS,CTNNB1,KRAS,PIK3CA,PTEN |
| 2.383e-02 | -3.74 | temporooccipital | COSMIC cancer mutations | temporooccipital | 7 | 5 | 16828 | 4835 |
CTNNB1,TP53,IDH1,CDKN2C,IDH2 |
| 2.383e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-NK-T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-NK-T_cell_lymphoma | 7 | 5 | 16828 | 4835 |
SF3B1,KRAS,CTNNB1,KIT,TP53 |
| 2.383e-02 | -3.74 | skin-face-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-face-adnexal_tumour-malignant_adnexal_tumour | 7 | 5 | 16828 | 4835 |
CTNNB1,KRAS,HRAS,PIK3CA,TP53 |
| 2.383e-02 | -3.74 | salivary_gland-pterygopalatine_fossa-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-pterygopalatine_fossa-carcinoma-adenoid_cystic_carcinoma | 7 | 5 | 16828 | 4835 |
PIK3CA,KRAS,HRAS,KIT,PTEN |
| 2.383e-02 | -3.74 | skin-forearm-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-forearm-carcinoma-squamous_cell_carcinoma | 7 | 5 | 16828 | 4835 |
TP53,TERT,KRAS,HRAS,NOTCH2 |
| 2.383e-02 | -3.74 | bone-vertebrae-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-vertebrae-chondrosarcoma-dedifferentiated | 7 | 5 | 16828 | 4835 |
IDH2,IDH1,TP53,PIK3CA,KRAS |
| 2.383e-02 | -3.74 | cervix-carcinoma-endometrioid_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endometrioid_adenocarcinoma | 7 | 5 | 16828 | 4835 |
PTEN,STK11,KRAS,TP53,PIK3CA |
| 2.383e-02 | -3.74 | central_nervous_system-supratentorial-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-supratentorial-glioma-astrocytoma_Grade_II | 7 | 5 | 16828 | 4835 |
KRAS,HRAS,TP53,IDH1,IDH2 |
| 2.383e-02 | -3.74 | desmoplastic_infantile_ganglioglioma | COSMIC cancer mutations | desmoplastic_infantile_ganglioglioma | 7 | 5 | 16828 | 4835 |
IDH2,SYN3,IDH1,TERT,KRAS |
| 2.383e-02 | -3.74 | bone-chest_wall-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-chest_wall-chondrosarcoma-dedifferentiated | 7 | 5 | 16828 | 4835 |
IDH2,IDH1,PIK3CA,TP53,KRAS |
| 2.383e-02 | -3.74 | soft_tissue-blood_vessel-haemangioblastoma | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioblastoma | 7 | 5 | 16828 | 4835 |
TP53,TERT,IDH2,PTEN,IDH1 |
| 2.383e-02 | -3.74 | blue | COSMIC cancer mutations | blue | 7 | 5 | 16828 | 4835 |
HRAS,GNA11,KIT,KRAS,GNAQ |
| 2.383e-02 | -3.74 | trichilemmoma | COSMIC cancer mutations | trichilemmoma | 7 | 5 | 16828 | 4835 |
PTEN,HRAS,CTNNB1,KRAS,PIK3CA |
| 2.383e-02 | -3.74 | salivary_gland-paranasal_sinus-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-paranasal_sinus-carcinoma-adenoid_cystic_carcinoma | 7 | 5 | 16828 | 4835 |
PIK3CA,KRAS,KIT,HRAS,PTEN |
| 2.383e-02 | -3.74 | central_nervous_system-parietooccipital-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-parietooccipital-glioma-astrocytoma_Grade_IV | 7 | 5 | 16828 | 4835 |
IDH1,MSH6,IDH2,EZH2,TP53 |
| 2.383e-02 | -3.74 | mixed_serous_and_endometrioid_carcinoma | COSMIC cancer mutations | mixed_serous_and_endometrioid_carcinoma | 7 | 5 | 16828 | 4835 |
PIK3CA,KRAS,CTNNB1,PPP2R1A,PTEN |
| 2.383e-02 | -3.74 | bone-radius-chondrosarcoma-conventional | COSMIC cancer mutations | bone-radius-chondrosarcoma-conventional | 7 | 5 | 16828 | 4835 |
IDH1,IDH2,KRAS,TP53,PIK3CA |
| 2.383e-02 | -3.74 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-MALT_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-MALT_lymphoma | 7 | 5 | 16828 | 4835 |
TP53,CALR,NOTCH2,EZH2,MYD88 |
| 2.383e-02 | -3.74 | endometrium-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-squamous_cell_carcinoma | 7 | 5 | 16828 | 4835 |
KRAS,CTNNB1,HRAS,PTEN,AKT1 |
| 2.383e-02 | -3.74 | sun_unexposed_site | COSMIC cancer mutations | sun_unexposed_site | 7 | 5 | 16828 | 4835 |
TP53,KIT,GNA11,HRAS,GNAQ |
| 2.383e-02 | -3.74 | endometrium-carcinoma-mixed_serous_and_endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_serous_and_endometrioid_carcinoma | 7 | 5 | 16828 | 4835 |
PPP2R1A,PTEN,PIK3CA,KRAS,CTNNB1 |
| 2.383e-02 | -3.74 | haemangioblastoma | COSMIC cancer mutations | haemangioblastoma | 7 | 5 | 16828 | 4835 |
IDH2,IDH1,PTEN,TERT,TP53 |
| 2.383e-02 | -3.74 | urinary_tract-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-carcinoma-transitional_cell_carcinoma | 7 | 5 | 16828 | 4835 |
MSH6,KRAS,HRAS,PIK3CA,TP53 |
| 2.388e-02 | -3.73 | mononuclear cell differentiation | biological process | GO:1903131 | 364 | 125 | 18204 | 5365 |
CSF2,DCLRE1C,NFIL3,CDK6,TNFSF8,TLR4,LEP,LRRC8A,CD40LG,SASH3,NKAP,CD79B,CD83,LARGE1,FOXP3,LILRB1,TRAF3IP2,BAX,IL6,AZI2,IL21,RSAD2,SLC39A7,CDC42,LEPR,MMP9,IFNA10,FOXP1,ITM2A,IL12B,TP53,FCER1G,IFNG,IFI16,LIPA,PPARG,PDP2,IFNA2,CD4,PTGER4,PSEN1,IFNK,PIK3R1,TPD52,CD3G,PIK3R2,PSMB11,MYD88,IRF1,JAK1,IL4,KDELR1,CBFB,VEGFA,B2M,CD28,ST3GAL1,IL7,ITK,EZH2,PDE1B,SOCS3,FBXO7,IFNB1,IL15,EGR1,WNT10B,RC3H2,CCR6,IFNA13,STAT6,PKNOX1,FCGR2B,ITGB8,CCR7,STK11,RPL22,BATF,CD1D,CEBPE,SYK,TOP2B,HMGB1,PTPN22,BCL6,PIR,RABL3,CTNNB1,TUSC2,TESPA1,BAK1,CTSK,IL2RG,CMTM7,TOX,NOTCH2,EP300,LMBR1L,UCP2,PIK3R3,IL10,RBPJ,LTBR,CCL19,NHEJ1,VPS54,IRF4,TGFBR2,IL2,DNAJB9,RHOH,TLR2,TRAF6,CEBPG,KIT,NDP,FOSL2,IL15RA,SYVN1,HDAC5,IRF8,RAG1,GPR89A,SLC25A5,FOS |
| 2.390e-02 | -3.73 | DAG1 (dystroglycan 1) | protein interactions | 1605 | 126 | 46 | 19454 | 5460 |
WWP2,DAG1,RHOG,NCK1,AGR2,SHC1,ATP6V1D,HRAS,RAB35,RAC2,PRNP,RHOH,CAV1,TUBA1A,CBLN4,SFTPC,SCPEP1,TNF,TNFSF8,KRAS,DRP2,CSK,NPTX1,CAV3,GGH,HFE,RHOB,BRCA1,LGALS8,LMBR1L,RHOJ,CSTF3,VIRMA,SRC,CLIC4,GINM1,PPP1CB,TMEM106A,CDC42,PRDX3,CCL3,WWP1,LARGE1,HMGB1,GPC1,CLEC12B |
| 2.392e-02 | -3.73 | epigenetic regulation of gene expression | biological process | GO:0040029 | 267 | 94 | 18204 | 5365 |
ARB2A,IFI16,RBM15B,APOBEC3F,H2AJ,NIBAN2,SUV39H1,BRCA1,HELLS,ZMPSTE24,HDAC3,MIR29A,EZH1,LHX2,EZH2,H3C1,ING2,PIWIL1,EGR1,SMARCB1,MECP2,SIN3A,POLE3,TRIM27,H2AC13,HDAC11,LMNB1,EED,PIWIL4,CBX3,SMARCA5,MORC2,NRDE2,BAHD1,PADI2,VPS72,MYC,MAEL,APEX1,TP53,PIK3CA,CGGBP1,PHF1,H2AZ2,H2AC1,H2AC4,APOBEC3A,CREBZF,PPM1D,H2AB1,SMCHD1,DIRAS3,OGG1,RB1,STPG4,GSK3A,LRIF1,HDAC5,H2AX,NDN,SPHK2,SDR16C5,MACROH2A1,WBP2,H2AC25,MIR29C,APOBEC3C,ALKBH4,MBD3,DDX4,PRMT5,SGF29,H2AC6,HDAC6,PIWIL2,RNF8,BCL6,MACROH2A2,PCGF3,HMGB1,MSL2,MIR182,LMNA,TRIM37,H2AC7,GPX1,PHB1,TRMT112,CBX5,RLIM,SIRT7,H2AZ1,EP300,DPY30 |
| 2.393e-02 | -3.73 | PKP4 (plakophilin 4) | protein interactions | 8502 | 148 | 53 | 19454 | 5460 |
GJA1,RAC2,RAB35,HRAS,DIRAS3,STX6,CAV1,ARF6,RHOH,CTNNB1,MOV10,TAX1BP3,PGAM1,SAV1,USP15,ARMC8,RHOG,PFDN1,PSEN1,FLOT1,KRAS,EPHA4,SOX2,RND3,CDH8,CAPZA2,UBASH3B,CTNNA1,ESR2,VIRMA,APEX1,MATR3,RHOJ,ARHGAP21,DNAJC5,RACGAP1,RAB2A,MYC,RAB11A,NTRK3,OSGEP,STK11,LAMTOR1,RHOB,TRIM23,TACR1,ATPAF2,RHOU,TACR3,GABARAP,RND2,CDC42,CCL3 |
| 2.395e-02 | -3.73 | DCAF4L1 (DDB1 and CUL4 associated factor 4 like 1) | protein interactions | 285429 | 22 | 11 | 19454 | 5460 |
SNRPA1,TCP1,CCT2,PFDN6,CCT7,PDRG1,CCT5,CCT8,RNF208,HSPD1,COPS5 |
| 2.395e-02 | -3.73 | WNT10B (Wnt family member 10B) | protein interactions | 7480 | 22 | 11 | 19454 | 5460 |
MCPH1,NEU1,JMJD8,NOTCH2,NDUFA2,FSTL1,DNAJC3,HSPA5,SKP1,LRP6,CLEC12B |
| 2.395e-02 | -3.73 | IGFBP7 (insulin like growth factor binding protein 7) | protein interactions | 3490 | 22 | 11 | 19454 | 5460 |
CUL3,VEGFA,RTN4,DSTN,CCL5,CNPY3,IGF1,TRIM37,RBBP8,CXCL10,CCL21 |
| 2.395e-02 | -3.73 | TCEAL7 (transcription elongation factor A like 7) | protein interactions | 56849 | 22 | 11 | 19454 | 5460 |
CSNK2B,WBP11,NEK2,GTF2F1,GTF2F2,DDX46,ARGLU1,RPP25,PRRC2A,DHX16,RP9 |
| 2.395e-02 | -3.73 | ACSS1 (acyl-CoA synthetase short chain family member 1) | protein interactions | 84532 | 22 | 11 | 19454 | 5460 |
IMMP2L,MALSU1,VAC14,TMEM70,PDHA1,RPA2,GATD3,PFDN5,RPA3,HSPD1,CREBBP |
| 2.395e-02 | -3.73 | PROC (protein C, inactivator of coagulation factors Va and VIIIa) | protein interactions | 5624 | 22 | 11 | 19454 | 5460 |
NPB,CSNK2B,F2,PROS1,SERPINA5,GGCX,PDF,UQCRH,SERPINB6,THBD,MATR3 |
| 2.395e-02 | -3.73 | TFR2 (transferrin receptor 2) | protein interactions | 7036 | 22 | 11 | 19454 | 5460 |
MAD2L2,PDF,TF,HFE,CFTR,GALNT12,EXT1,SOCS3,CD81,SEC22A,TAF5L |
| 2.395e-02 | -3.73 | STAP1 (signal transducing adaptor family member 1) | protein interactions | 26228 | 22 | 11 | 19454 | 5460 |
CAPZA2,KIT,CCND3,CAPZA1,MET,GAB1,ATG16L1,AR,CD2AP,RETREG3,SCPEP1 |
| 2.395e-02 | -3.73 | TNFRSF11A (TNF receptor superfamily member 11a) | protein interactions | 8792 | 22 | 11 | 19454 | 5460 |
DDX39A,TRAF2,SEC61B,CUL3,TNFRSF1B,CBL,TAB2,SP1,TRAF1,SRC,TRAF6 |
| 2.395e-02 | -3.73 | TMEM98 (transmembrane protein 98) | protein interactions | 26022 | 22 | 11 | 19454 | 5460 |
ATP1B3,STOM,BMPR1A,VAMP3,STX8,SGTA,HNRNPL,GJB1,STX6,STX7,VAMP8 |
| 2.395e-02 | -3.73 | KCNA1 (potassium voltage-gated channel subfamily A member 1) | protein interactions | 3736 | 22 | 11 | 19454 | 5460 |
SGTA,RTN4,DLG1,DLG4,CNTNAP1,KCNA2,JAGN1,TMEM14B,KCNA3,FCER1G,DOLK |
| 2.395e-02 | -3.73 | TP53INP1 (tumor protein p53 inducible nuclear protein 1) | protein interactions | 94241 | 22 | 11 | 19454 | 5460 |
TBC1D4,TP53,E2F4,GABARAPL2,ASPM,SEC22A,GABARAPL1,HNRNPL,GABARAP,SQSTM1,MAP1LC3A |
| 2.395e-02 | -3.73 | ZNF704 (zinc finger protein 704) | protein interactions | 619279 | 22 | 11 | 19454 | 5460 |
ING2,KRT8,BRMS1,SAP30,SIN3A,SAP30L,VIRMA,HNRNPL,HDAC3,FBXW11,BRMS1L |
| 2.395e-02 | -3.73 | CRACR2B (calcium release activated channel regulator 2B) | protein interactions | 283229 | 22 | 11 | 19454 | 5460 |
IDH1,ZBTB25,SPPL3,TIMM29,CFTR,BAG3,DDX39A,USP2,PSMB3,CARD19,GHITM |
| 2.395e-02 | -3.73 | NARF (nuclear prelamin A recognition factor) | protein interactions | 26502 | 22 | 11 | 19454 | 5460 |
PRPF4,CUL3,ISCA2,STAT5A,LMNA,SEM1,BOLA2B,KCTD17,SFRP4,CBX5,APEX1 |
| 2.395e-02 | -3.73 | ND2 (NADH dehydrogenase subunit 2) | protein interactions | 4536 | 22 | 11 | 19454 | 5460 |
PRNP,HSCB,SRC,CCDC90B,NDUFB5,NDUFC2,NDUFS3,NDUFS6,SMAD4,STK11,TIMMDC1 |
| 2.395e-02 | -3.73 | IRGQ (immunity related GTPase Q) | protein interactions | 126298 | 22 | 11 | 19454 | 5460 |
GABARAPL2,ATP6V1A,MAP1LC3B,MAP1LC3A,SCG3,NFYA,NPC2,PRNP,XPNPEP1,KCTD10,SLC25A32 |
| 2.395e-02 | -3.73 | RGS14 (regulator of G protein signaling 14) | protein interactions | 10636 | 22 | 11 | 19454 | 5460 |
RAP2A,TRAF2,RND2,GNAO1,XPO1,RAP1A,GNA11,NFKB1,GNAI2,GNAI3,RND3 |
| 2.400e-02 | -3.73 | Amoebiasis | KEGG pathways | ko05146 | 94 | 42 | 7161 | 2463 |
PLCB1,ARG2,IL1R2,RAB5A,IL12B,IL12A,COL3A1,PRKACB,CXCL8,TLR4,TGFB3,SERPINB9,CSF2,TGFB2,PIK3R1,SERPINB10,GNA11,CD14,GNA14,ACTN4,GNAQ,PIK3R2,PLCB2,CXCL1,RAB5C,IFNG,IL10,SERPINB1,PRKCA,PIK3R3,TLR2,IL6,IL1B,PIK3CA,COL1A2,TNF,HSPB1,CD1D,LAMB2,SERPINB6,NFKB1,PRKCB |
| 2.400e-02 | -3.73 | Amoebiasis | KEGG pathways | hsa05146 | 94 | 42 | 7161 | 2463 |
TLR4,PRKACB,CXCL8,COL3A1,IL12A,IL12B,RAB5A,IL1R2,PLCB1,ARG2,RAB5C,IFNG,CXCL1,PLCB2,PIK3R2,GNAQ,CD14,GNA14,ACTN4,GNA11,SERPINB9,TGFB2,PIK3R1,CSF2,TGFB3,SERPINB10,TNF,HSPB1,COL1A2,PIK3CA,IL1B,IL6,PIK3R3,TLR2,PRKCA,IL10,SERPINB1,PRKCB,SERPINB6,NFKB1,LAMB2,CD1D |
| 2.403e-02 | -3.73 | SNARE binding | molecular function | GO:0000149 | 107 | 42 | 18094 | 5411 |
SNAP29,CPLX1,HECTD3,SYT2,PICALM,STX5,STX17,SNAP23,SNAPIN,VAMP1,STX10,SNAP25,VAMP8,KCNB1,STX12,CPLX2,VTI1B,STX1A,TMED9,SYT4,VPS18,EXOC3,DAPK1,STX6,GOSR2,SCFD1,STXBP1,VPS54,RAB11A,CPLX3,SNAP91,STX7,VAMP2,NAPG,STX8,SLC6A4,VAMP3,STX16,VAMP7,GABARAPL2,NAPA,STX11 |
| 2.404e-02 | -3.73 | SHCBP1L (SHC binding and spindle associated 1 like) | protein interactions | 81626 | 5 | 4 | 19454 | 5460 |
FZR1,KRAS,BRAP,H1-1 |
| 2.404e-02 | -3.73 | Cdk2 (cyclin dependent kinase 2) | protein interactions | 12566 | 5 | 4 | 19454 | 5460 |
H1-5,CCNF,RB1,H1-1 |
| 2.404e-02 | -3.73 | CCR4 (CCR4-NOT core exoribonuclease subunit CCR4) | protein interactions | 851212 | 5 | 4 | 19454 | 5460 |
CNOT8,NUP62,CNOT7,BRCA1 |
| 2.404e-02 | -3.73 | ERICH2 (glutamate rich 2) | protein interactions | 285141 | 5 | 4 | 19454 | 5460 |
FBXO7,MACROH2A1,SDCBP,PSORS1C2 |
| 2.404e-02 | -3.73 | POLR2A (RNA polymerase II subunit A) | protein interactions | 282312 | 5 | 4 | 19454 | 5460 |
CCNH,CDK9,CDK7,BRCA1 |
| 2.404e-02 | -3.73 | HTR7 (5-hydroxytryptamine receptor 7) | protein interactions | 3363 | 5 | 4 | 19454 | 5460 |
MATR3,CUL3,GPRASP2,RHOBTB3 |
| 2.404e-02 | -3.73 | Mad2l1 (mitotic arrest deficient 2 like 1) | protein interactions | 297176 | 5 | 4 | 19454 | 5460 |
MAD2L1,CDC20,BUB3,MAD2L1BP |
| 2.404e-02 | -3.73 | Rab38 (RAB38, member RAS oncogene family) | protein interactions | 72433 | 5 | 4 | 19454 | 5460 |
SMAD3,BMPR1B,SMAD4,SMAD2 |
| 2.404e-02 | -3.73 | ZNF253 (zinc finger protein 253) | protein interactions | 56242 | 5 | 4 | 19454 | 5460 |
FAXC,FBLN5,NOTCH2,RPL27A |
| 2.404e-02 | -3.73 | CYP3A7 (cytochrome P450 family 3 subfamily A member 7) | protein interactions | 1551 | 5 | 4 | 19454 | 5460 |
VAPB,CYP3A5,CYSTM1,ODR4 |
| 2.404e-02 | -3.73 | IGHV3-64D (immunoglobulin heavy variable 3-64D) | protein interactions | 102723170 | 5 | 4 | 19454 | 5460 |
UFL1,MYC,FBXO22,UBE2H |
| 2.404e-02 | -3.73 | GABRQ (gamma-aminobutyric acid type A receptor subunit theta) | protein interactions | 55879 | 5 | 4 | 19454 | 5460 |
TXNDC12,CLEC2B,GNMT,VIRMA |
| 2.404e-02 | -3.73 | Rhoj (ras homolog family member J) | protein interactions | 80837 | 5 | 4 | 19454 | 5460 |
SMAD4,BMPR1B,ACVR1,SMAD2 |
| 2.404e-02 | -3.73 | GABRG3 (gamma-aminobutyric acid type A receptor subunit gamma3) | protein interactions | 2567 | 5 | 4 | 19454 | 5460 |
TP53,GABRA1,GABARAP,DDRGK1 |
| 2.404e-02 | -3.73 | GSAP (gamma-secretase activating protein) | protein interactions | 54103 | 5 | 4 | 19454 | 5460 |
PSENEN,HSP90B1,NCSTN,PSEN1 |
| 2.404e-02 | -3.73 | ZBED5 (zinc finger BED-type containing 5) | protein interactions | 58486 | 5 | 4 | 19454 | 5460 |
AMIGO1,MYC,SMAD4,CCND1 |
| 2.404e-02 | -3.73 | Rras2 (related RAS viral (r-ras) oncogene 2) | protein interactions | 66922 | 5 | 4 | 19454 | 5460 |
ACVR1,BMPR1B,SMAD3,SMAD4 |
| 2.404e-02 | -3.73 | Sel1l (sel-1 suppressor of lin-12-like (C. elegans)) | protein interactions | 20338 | 5 | 4 | 19454 | 5460 |
HSP90B1,ERLEC1,OS9,HM13 |
| 2.404e-02 | -3.73 | Hk3 (hexokinase 3) | protein interactions | 25060 | 5 | 4 | 19454 | 5460 |
LEP,PTGDS,IGFBP4,ZBTB17 |
| 2.404e-02 | -3.73 | ATP8B3 (ATPase phospholipid transporting 8B3) | protein interactions | 148229 | 5 | 4 | 19454 | 5460 |
SPTAN1,JUN,APEX1,ATP8A1 |
| 2.404e-02 | -3.73 | UCN (urocortin) | protein interactions | 7349 | 5 | 4 | 19454 | 5460 |
CRHBP,LEP,DDX39A,CRHR1 |
| 2.404e-02 | -3.73 | Birc6 (baculoviral IAP repeat-containing 6) | protein interactions | 12211 | 5 | 4 | 19454 | 5460 |
GABARAPL1,MAP1LC3B,GABARAPL2,GABARAP |
| 2.404e-02 | -3.73 | SPDYE1 (speedy/RINGO cell cycle regulator family member E1) | protein interactions | 285955 | 5 | 4 | 19454 | 5460 |
CDK5,CDKN1B,RIT1,CDK1 |
| 2.404e-02 | -3.73 | BAIAP3 (BAI1 associated protein 3) | protein interactions | 8938 | 5 | 4 | 19454 | 5460 |
PHB1,HNRNPL,APEX1,DDX39A |
| 2.404e-02 | -3.73 | MAN1C1 (mannosidase alpha class 1C member 1) | protein interactions | 57134 | 5 | 4 | 19454 | 5460 |
HNRNPL,MYG1,SMAD9,FAM241A |
| 2.404e-02 | -3.73 | PIGC (phosphatidylinositol glycan anchor biosynthesis class C) | protein interactions | 5279 | 5 | 4 | 19454 | 5460 |
DPM2,ACACA,KLF10,ZHX1 |
| 2.404e-02 | -3.73 | Map3k7 (mitogen-activated protein kinase kinase kinase 7) | protein interactions | 26409 | 5 | 4 | 19454 | 5460 |
TAB1,TRAF6,SMURF1,TAB2 |
| 2.404e-02 | -3.73 | OR2L13 (olfactory receptor family 2 subfamily L member 13) | protein interactions | 284521 | 5 | 4 | 19454 | 5460 |
SERPINA1,ALB,CDSN,GPX7 |
| 2.404e-02 | -3.73 | CGB8 (chorionic gonadotropin subunit beta 8) | protein interactions | 94115 | 5 | 4 | 19454 | 5460 |
CFTR,RIT1,KRAS,SMCP |
| 2.404e-02 | -3.73 | TSACC (TSSK6 activating cochaperone) | protein interactions | 128229 | 5 | 4 | 19454 | 5460 |
KDM1A,LIX1,FOXP2,DDX39A |
| 2.404e-02 | -3.73 | Rhobtb1 (Rho-related BTB domain containing 1) | protein interactions | 69288 | 5 | 4 | 19454 | 5460 |
ACVR1,BMPR1B,SMAD2,SMURF1 |
| 2.404e-02 | -3.73 | CYP2A6 (cytochrome P450 family 2 subfamily A member 6) | protein interactions | 1548 | 5 | 4 | 19454 | 5460 |
POR,HAPSTR1,RABAC1,CYB5A |
| 2.404e-02 | -3.73 | ALKBH1 (alkB homolog 1, histone H2A dioxygenase) | protein interactions | 8846 | 5 | 4 | 19454 | 5460 |
PSMD14,MYC,DNAJB6,HAPSTR1 |
| 2.404e-02 | -3.73 | S100a6 (S100 calcium binding protein A6 (calcyclin)) | protein interactions | 20200 | 5 | 4 | 19454 | 5460 |
FAIM,CFTR,TOMM70,HSP90AA1 |
| 2.404e-02 | -3.73 | SCARNA5 (small Cajal body-specific RNA 5) | protein interactions | 677775 | 5 | 4 | 19454 | 5460 |
MOV10,SIRT7,VIRMA,RIGI |
| 2.404e-02 | -3.73 | GPX3 (glutathione peroxidase 3) | protein interactions | 2878 | 5 | 4 | 19454 | 5460 |
TP53I3,CCR1,AGPAT1,GPX3 |
| 2.404e-02 | -3.73 | ZFP28 (ZFP28 zinc finger protein) | protein interactions | 140612 | 5 | 4 | 19454 | 5460 |
HMOX2,PRKRA,PPP2CB,KDM1A |
| 2.404e-02 | -3.73 | Blzf1 (basic leucine zipper nuclear factor 1) | protein interactions | 66352 | 5 | 4 | 19454 | 5460 |
GORASP2,TNKS,RHEB,TCP11L1 |
| 2.404e-02 | -3.73 | SLC16A14 (solute carrier family 16 member 14) | protein interactions | 151473 | 5 | 4 | 19454 | 5460 |
GNAQ,HNRNPL,YES1,SVIP |
| 2.404e-02 | -3.73 | CFAP251 (cilia and flagella associated protein 251) | protein interactions | 144406 | 5 | 4 | 19454 | 5460 |
CLK1,RIGI,HSPB1,ESR2 |
| 2.404e-02 | -3.73 | PTGER2 (prostaglandin E receptor 2) | protein interactions | 5732 | 5 | 4 | 19454 | 5460 |
PTGES,PTGDS,PTGFR,SRC |
| 2.404e-02 | -3.73 | DEFB4A (defensin beta 4A) | protein interactions | 1673 | 5 | 4 | 19454 | 5460 |
TLR4,ZMPSTE24,KCNA3,CCR6 |
| 2.404e-02 | -3.73 | GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2) | protein interactions | 2570 | 5 | 4 | 19454 | 5460 |
MAP1B,CSNK2A1,PRKCA,SQSTM1 |
| 2.404e-02 | -3.73 | C18orf63 (chromosome 18 open reading frame 63) | protein interactions | 644041 | 5 | 4 | 19454 | 5460 |
WTAP,METTL14,EZH2,MYC |
| 2.404e-02 | -3.73 | S100A12 (S100 calcium binding protein A12) | protein interactions | 6283 | 5 | 4 | 19454 | 5460 |
TNF,AGER,CACYBP,RIGI |
| 2.404e-02 | -3.73 | SEMA3G (semaphorin 3G) | protein interactions | 56920 | 5 | 4 | 19454 | 5460 |
RIGI,UFL1,DESI2,RHOU |
| 2.404e-02 | -3.73 | IGFBPL1 (insulin like growth factor binding protein like 1) | protein interactions | 347252 | 5 | 4 | 19454 | 5460 |
SNX5,CUL3,SNX1,SNX2 |
| 2.404e-02 | -3.73 | THAP9 (THAP domain containing 9) | protein interactions | 79725 | 5 | 4 | 19454 | 5460 |
MRPL9,MRPL50,YWHAZ,KCTD17 |
| 2.404e-02 | -3.73 | Ska1 (spindle and kinetochore associated complex subunit 1) | protein interactions | 66468 | 5 | 4 | 19454 | 5460 |
HSPD1,SKA3,CCAR2,SKA2 |
| 2.404e-02 | -3.73 | CRYGA (crystallin gamma A) | protein interactions | 1418 | 5 | 4 | 19454 | 5460 |
HSPA13,AGR2,PSMB9,TRAF1 |
| 2.405e-02 | -3.73 | translation initiation factor activity | molecular function | GO:0003743 | 50 | 22 | 18094 | 5411 |
EIF1AD,EIF4H,EIF4E,EIF4E2,EIF4E3,EIF2B5,EIF3E,EIF2D,EIF2B3,EIF3K,EIF3J,COPS5,EIF1AX,EIF2B2,EIF4B,EIF4A2,EIF1B,EIF2S1,EIF2S2,EIF3D,EIF3G,EIF5B |
| 2.406e-02 | -3.73 | ATF6 (ATF6-alpha) activates chaperones | REACTOME pathways | R-HSA-381033 | 13 | 8 | 10285 | 3229 |
HSP90B1,HSPA5,CALR,ATF4,NFYA,DDIT3,NFYB,XBP1 |
| 2.406e-02 | -3.73 | Downregulation of ERBB2:ERBB3 signaling | REACTOME pathways | R-HSA-1358803 | 13 | 8 | 10285 | 3229 |
AKT2,USP8,RNF41,AKT3,AKT1,UBB,RPS27A,UBA52 |
| 2.406e-02 | -3.73 | FCGR activation | REACTOME pathways | R-HSA-2029481 | 13 | 8 | 10285 | 3229 |
FCGR1A,SYK,FCGR2A,YES1,CD247,CD3G,SRC,FGR |
| 2.406e-02 | -3.73 | AKT phosphorylates targets in the cytosol | REACTOME pathways | R-HSA-198323 | 13 | 8 | 10285 | 3229 |
AKT3,AKT1,CDKN1B,MDM2,AKT2,CDKN1A,BAD,GSK3A |
| 2.407e-02 | -3.73 | FOXRED2 (FAD dependent oxidoreductase domain containing 2) | protein interactions | 80020 | 92 | 35 | 19454 | 5460 |
ERLEC1,HSCB,VDAC1,CLPB,RAB9A,SLC25A10,LIN7C,BCKDK,TMEM106B,NCR3,CASK,RPN1,TUBA1A,NDUFAF3,PI15,EGLN3,FIBIN,RPL10,OS9,DNAJB9,GANAB,DNASE1L1,CHCHD6,VDAC2,LMBR1L,SDF2L1,DNAJC10,LCN6,TOMM40,GGH,FEM1B,TNFAIP6,SAV1,DPY30,EDEM1 |
| 2.407e-02 | -3.73 | GPR12 (G protein-coupled receptor 12) | protein interactions | 2835 | 92 | 35 | 19454 | 5460 |
SLC20A1,FITM2,TMEM164,SLC25A28,ATP1A3,COX16,DEGS1,ATP5MC1,FAM241A,SLC30A5,PARL,SLC25A17,SC5D,SPPL3,TLCD2,ABHD17A,GPR89A,GJA1,ELOVL4,SCAMP2,ACSL4,SYNGR3,LMBRD2,SLC29A1,ADIPOR1,DAAM1,SLC19A2,SLC35F6,CERS6,SLC5A6,SLC25A14,PXMP2,RAB9A,SLC35G2,ORMDL1 |
| 2.407e-02 | -3.73 | NAE1 (NEDD8 activating enzyme E1 subunit 1) | protein interactions | 8883 | 92 | 35 | 19454 | 5460 |
TUFM,XPO1,TMEM183A,LMNB1,UBE2H,DNAJC7,FBXO32,RPS12,MSN,PRNP,WIF1,APEX1,UBA3,EGLN3,TXNRD1,NAA15,NUDCD3,JUN,UBE2F,RPA2,UBE2M,CAPN2,BAP1,RPA3,LIPA,SQSTM1,DDX5,NSFL1C,PAFAH1B2,KRAS,NEDD8,PPP1R2,GTF2I,SAR1B,CAPZA1 |
| 2.409e-02 | -3.73 | PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha) | protein interactions | 5305 | 199 | 69 | 19454 | 5460 |
FAM98A,PRNP,NKAP,LYAR,ST6GAL1,DDX23,NOS1AP,MED4,BRD3,IFI16,EDEM1,ZCCHC10,PPIL4,TMA16,CSNK2A1,KRAS,MEPCE,AHCYL1,STRADB,TCOF1,PDIA6,SRSF8,DDX42,NFKBIL1,RAB4A,ZRANB2,GPBP1L1,TAF2,RPS23,MAX,CSNK1E,RPSA,TULP3,PPP1R10,EAF2,TACO1,PSPC1,EIF3K,CTTN,SF3B4,CSNK2B,CAB39,GTF2F1,MECP2,PIP4K2C,CA2,STK11,UBE2H,PPIG,MYC,GSTK1,RIOK2,MTPN,STAU1,ATG4C,CXXC1,SKP1,RPA3,CXCR4,PRPF4,XRCC5,ATP5IF1,CSNK1A1L,RPA2,NUFIP2,CSNK1A1,RPS14,PIP5K1A,ZNF428 |
| 2.410e-02 | -3.73 | human chr9p24.1 | chromosome location | human chr9p24.1 | 27 | 11 | 26134 | 5823 |
CD274,RCL1,PLPP6,JAK2,PDCD1LG2,RANBP6,CDC37L1,RLN2,MIR101-2,PLGRKT,AK3 |
| 2.411e-02 | -3.73 | Signaling by Ligand-Responsive EGFR Variants in Cancer | REACTOME pathways | R-HSA-5637815 | 20 | 11 | 10285 | 3229 |
SHC1,GAB1,HRAS,PIK3R1,KRAS,UBA52,RPS27A,UBB,HSP90AA1,PIK3CA,CBL |
| 2.411e-02 | -3.73 | Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | REACTOME pathways | R-HSA-1236382 | 20 | 11 | 10285 | 3229 |
PIK3R1,SHC1,KRAS,HRAS,GAB1,UBB,HSP90AA1,PIK3CA,CBL,UBA52,RPS27A |
| 2.411e-02 | -3.73 | Signaling by EGFR in Cancer | REACTOME pathways | R-HSA-1643713 | 20 | 11 | 10285 | 3229 |
RPS27A,UBA52,HSP90AA1,CBL,PIK3CA,UBB,HRAS,GAB1,SHC1,KRAS,PIK3R1 |
| 2.411e-02 | -3.73 | BAZ1B (bromodomain adjacent to zinc finger domain 1B) | protein interactions | 9031 | 183 | 64 | 19454 | 5460 |
RPA3,SIRT7,SF3B1,EP300,NUCKS1,STAU1,FBXW7,MBD3,UTP23,ACTL6A,RPA2,LMNA,GRM2,ZNF330,RPL7L1,DEK,APEX1,ESR2,RPL10,VIRMA,SMARCA5,MYC,SMARCE1,H2BC9,EXOSC1,MAPRE1,TOP2B,PCNA,H3C1,RIGI,ZNF263,SUPT5H,H2AX,SOX2,CBX3,SKA3,NECAP1,HDAC11,CHMP4C,ALPL,POLR2C,HBP1,SMARCB1,NUPR1,H2AZ1,KRR1,EED,RPS10,FZR1,LYAR,CGAS,SUMO2,TOP1,ZBTB2,KLF9,HMGA1,IFI16,NR4A2,NCK1,KPNA1,CDK12,ANKRD50,LHX2,BRD3 |
| 2.411e-02 | -3.73 | CNTRL (centriolin) | protein interactions | 11064 | 183 | 64 | 19454 | 5460 |
HAUS2,ZNF326,CDK7,KDELR2,IDH3B,ATG16L1,WDR83,H1-5,HSPA5,PACSIN3,CSRP1,SSR3,SRSF2,RAB9A,SQSTM1,TMEM256,H1-1,PSMD14,CKB,MTPN,ARHGAP21,CCNB1,CSK,CREBBP,SYCE3,RAB2A,VIRMA,RPGRIP1L,DAPK3,ZNF622,MGST3,MSN,GANAB,CYB5R3,POLR2C,PDHA1,TUBB4B,VPS33A,ERLIN2,RPAP2,TP53,NAA15,HSDL2,TBK1,TRIM26,SLC39A7,HSPD1,MED4,SSX2IP,PSMD7,AGR2,TRA2A,SPATA2,ABRACL,YWHAH,PDIA3,CALR,RAB11B,SLAIN2,DBT,ARF6,PWP2,DNM2,RAB35 |
| 2.411e-02 | -3.72 | CXCR3-mediated signaling events | Pathway Interaction DB | cxcr3pathway | 34 | 18 | 2226 | 782 |
CXCR3,MAP2K1,CXCL10,CXCL11,MAP2K3,PIK3R1,GNB1,PIK3CA,SRC,GNAI2,RAF1,MAP2K6,CCL11,CXCL9,GNAI3,AKT1,GNG2,CXCL13 |
| 2.412e-02 | -3.72 | central_nervous_system-brain-glioma-astrocytoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma | 35 | 16 | 16828 | 4835 |
PIK3CA,TERT,PTEN,SMARCB1,TP53,CTNNB1,KIT,IDH2,CDKN2C,NF2,AKT1,PTPN11,SF3B1,KRAS,HRAS,IDH1 |
| 2.415e-02 | -3.72 | multicellular organismal-level homeostasis | biological process | GO:0048871 | 609 | 202 | 18204 | 5365 |
PPP2R1A,SUV39H1,CHMP5,ZNHIT1,PRKACB,TRIM10,CLDN12,F11R,KLF1,UFL1,RACGAP1,RPS24,LIPA,EMX1,SFXN1,SIT1,EGR1,ARMCX1,ALPL,MKKS,GAPT,CNTN2,NCDN,SERPINA3,CLN8,FSTL1,EPO,IL7,EZH2,ADGRG1,VEGFA,B2M,NCSTN,SRC,ADORA1,PIWIL4,SGIP1,NKIRAS1,ANGPT1,PRDX1,EXT1,PBLD,PRDX2,RAC2,PDE4B,LEP,SQSTM1,TLR4,PTPN11,SNX10,SLC39A3,NLE1,PIK3CA,SOD2,LEPR,LGR4,NEO1,TRAF6,AIPL1,TSPO2,G6PD,LDB1,CEBPG,SLC12A2,NDP,CD2AP,CFTR,GJA1,BPGM,CLDN3,VPS54,CCR2,SFTPD,NDN,GPRASP2,IL2RA,SLC11A2,HCLS1,ANKH,SLC25A5,RB1,NKIRAS2,DRD1,RAG1,HFE,BCL6,MPIG6B,HMGB1,MBL2,PROM1,CCR4,CYP4F12,STK11,AKR1B1,FOXA3,HDAC6,HSCB,MYCT1,PKNOX1,ACTB,CYP11B2,SLC2A1,LACRT,ESAM,GPAM,CCN3,CYBRD1,TRIM32,CX3CR1,DBH,TMOD3,RDH12,MAEA,OCIAD2,TLR9,ILDR1,IL20RB,MLLT6,INHA,LPCAT3,AQP3,AQP4,CLDN1,POC1B,MIR204,AQP2,RC3H2,WDR37,VSTM4,LYAR,MEF2C,CIB2,TP53INP2,IREB2,NCAPG2,PMAIP1,BAP1,CD36,FOXP3,AKT3,HTR2A,ERRFI1,SASH3,SLC48A1,SMAD5,ADRB1,RPS17,LDB2,SOS2,RPS14,HCRT,FMO2,ACVR1C,UBB,CAMLG,TRAF3IP2,BAX,FLCN,IL6,MTF1,FAS,SART3,SOX9,KIT,ADRB3,PRCP,PICALM,RRN3,SOD1,ARRDC3,CYTL1,ATP5IF1,ACP5,JAK2,NLRP6,CLRN1,ACACA,TUBA1A,CD34,OAS1,FOSL2,CDK5RAP3,FMO1,AKT1,IL1B,RMI1,COL3A1,ADRB2,CCR7,IL1A,KRAS,POLB,LCA5,GPX1,RAB3D,SLC1A1,CTNNB1,TNFAIP3,CTSK,HYAL2,RHAG,BAK1 |
| 2.415e-02 | -3.72 | malignant_adnexal_tumour | COSMIC cancer mutations | malignant_adnexal_tumour | 19 | 10 | 16828 | 4835 |
TP53,KRAS,CTNNB1,HRAS,KIT,AKT1,IDH1,JAK2,PIK3CA,PTEN |
| 2.415e-02 | -3.72 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 19 | 10 | 16828 | 4835 |
TP53,HRAS,RB1,KRAS,JAK2,IDH1,MYD88,EZH2,PTEN,SF3B1 |
| 2.416e-02 | -3.72 | ACTR3B (actin related protein 3B) | protein interactions | 57180 | 53 | 22 | 19454 | 5460 |
NCKIPSD,CCT2,XPO1,EXOC5,STK4,ACTR3B,CMSS1,CCT7,NDP,TCP1,CCAR2,RTRAF,ENO1,RSRC1,PDCL,NUPR1,ACTR2,ARPC3,CFTR,CDK4,ARPC2,CCT8 |
| 2.416e-02 | -3.72 | PRRC1 (proline rich coiled-coil 1) | protein interactions | 133619 | 53 | 22 | 19454 | 5460 |
CERS2,PAFAH1B2,FERMT2,SAR1B,RAB1A,DLG1,TSG101,HSPA8,SEC23A,FYTTD1,POU5F1,CBL,NRP1,DNAJB6,HNRNPAB,SHMT1,SNRNP27,YWHAH,SOX2,PPIB,YWHAG,HNRNPA1 |
| 2.416e-02 | -3.72 | TMEM242 (transmembrane protein 242) | protein interactions | 729515 | 53 | 22 | 19454 | 5460 |
JAGN1,SFXN1,ATP6V0B,RNF5,FBXW7,TMBIM1,APOO,MFSD6,TMEM31,GHITM,PLP1,ELOVL4,HSD17B11,GGT7,SLC19A3,HNRNPL,PARL,MSMO1,SYNJ2BP,CYB561,SLC6A1,TMEM179B |
| 2.416e-02 | -3.72 | CDK10 (cyclin dependent kinase 10) | protein interactions | 8558 | 53 | 22 | 19454 | 5460 |
ACTA2,H2AZ1,GTF2H2,ACTB,INA,HSP90AB1,PDCD5,CACYBP,GMNN,CCNQ,FBXO7,CCT2,TFDP2,HSP90AA1,MGMT,SEMG2,HSPA8,RNF115,CCR4,SKP1,CCNA2,TMEM94 |
| 2.416e-02 | -3.72 | HS6ST2 (heparan sulfate 6-O-sulfotransferase 2) | protein interactions | 90161 | 53 | 22 | 19454 | 5460 |
DPP4,LCN6,GGH,SDF2L1,YWHAZ,LMBR1L,FAM3A,NRSN1,TSPAN18,DNAJB9,GINM1,NETO2,TMEM106A,TMEM59,SFTPC,CHRNB2,OGFOD3,NCR3,CHST10,TNF,CD1B,CLEC12B |
| 2.422e-02 | -3.72 | Oxidative Stress | WikiPathways | WP408 | 31 | 17 | 5310 | 1910 |
TXNRD1,SP1,SOD3,GCLC,SOD1,TXNRD2,GPX1,GPX3,NFKB1,JUNB,NQO1,MT1X,CYP1A1,SOD2,NFE2L2,FOS,MAPK10 |
| 2.426e-02 | -3.72 | TSG101 (tumor susceptibility 101) | protein interactions | 7251 | 280 | 94 | 19454 | 5460 |
EWSR1,PABPC1,TFG,SNAPIN,ACTN4,JUN,RNF126,HGS,GJA1,TSG101,FBXO32,CD63,EGLN3,PEG10,TRIM35,XPO1,HNRNPA1,LAMP2,WWP2,CBL,WDR12,BIRC2,EP300,RAB5A,RNF41,CCND3,ADRB2,CDKN1A,ASZ1,HSH2D,IRF2BPL,NUFIP2,EIF4B,PIP4P2,SCN2B,S1PR4,TOM1L1,ESR2,TAX1BP1,TRIM46,BTF3,CDKN2D,KLK5,FYTTD1,MYD88,PDE2A,CNOT7,TOM1,RASL10B,TOLLIP,MTA3,TP53,DMAP1,MDM2,PRNP,CGAS,MOV10,EDEM1,MZB1,PROM1,SMCHD1,CD9,RAB9A,DLAT,RPA3,PIAS1,VPS28,AATF,LITAF,CERS2,NF2,FBXW7,CD2AP,PCK2,UBA52,SH3GLB2,TFIP11,UBAP1,RPA2,FGFR1,KLK6,UBE2I,ALG2,ROCK1,DAPK3,TRIM54,CHMP5,AR,NONO,CCHCR1,STK11,EPHA2,NIF3L1,TRIM23 |
| 2.429e-02 | -3.72 | penis | COSMIC cancer mutations | penis | 14 | 8 | 16828 | 4835 |
TP53,HRAS,KIT,KRAS,PTEN,TERT,PIK3CA,STK11 |
| 2.429e-02 | -3.72 | large_intestine-rectum-adenoma-tubular | COSMIC cancer mutations | large_intestine-rectum-adenoma-tubular | 14 | 8 | 16828 | 4835 |
STK11,KRAS,CTNNB1,PIK3CA,PIK3R1,PTEN,SMAD4,FBXW7 |
| 2.429e-02 | -3.72 | urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma | 14 | 8 | 16828 | 4835 |
PTEN,TERT,PIK3CA,MSH6,TP53,HRAS,KRAS,CTNNB1 |
| 2.429e-02 | -3.72 | large_intestine-rectum-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-rectum-adenoma-tubulovillous | 14 | 8 | 16828 | 4835 |
PIK3CA,STK11,SMAD4,PTEN,KRAS,CTNNB1,FBXW7,PIK3R1 |
| 2.429e-02 | -3.72 | endometriosis | COSMIC cancer mutations | endometriosis | 14 | 8 | 16828 | 4835 |
PTEN,PIK3CA,AKT1,HRAS,KRAS,CTNNB1,BRCA1,TP53 |
| 2.429e-02 | -3.72 | central_nervous_system-brain-other-ganglioglioma | COSMIC cancer mutations | central_nervous_system-brain-other-ganglioglioma | 14 | 8 | 16828 | 4835 |
PTEN,TERT,PIK3CA,IDH2,AKT1,IDH1,KLF4,CTNNB1 |
| 2.429e-02 | -3.72 | fallopian_tube-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | fallopian_tube-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 14 | 8 | 16828 | 4835 |
AKT1,JAK2,CTNNB1,KRAS,KIT,TP53,PTEN,PIK3CA |
| 2.429e-02 | -3.72 | vagina-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | vagina-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 14 | 8 | 16828 | 4835 |
PTEN,PIK3CA,AKT1,JAK2,CTNNB1,KRAS,KIT,TP53 |
| 2.431e-02 | -3.72 | PCGF3 (polycomb group ring finger 3) | protein interactions | 10336 | 89 | 34 | 19454 | 5460 |
CSNK2A1,CREBBP,PFDN5,PFDN4,HSP90AA1,PFDN2,PFDN6,CCT2,MYO6,UBE2E3,CSNK2B,RB1,ESR2,HNRNPL,MBL2,EGR2,CCT5,E2F6,PHC1,CBX3,KLF3,PGK1,RING1,YAF2,PCGF2,CCT8,SKP1,PCGF6,UBE2D3,PCGF3,TRIM63,HNRNPK,CBX7,TGIF2LX |
| 2.433e-02 | -3.72 | STAT5A (signal transducer and activator of transcription 5A) | protein interactions | 6776 | 123 | 45 | 19454 | 5460 |
PDHB,FBXW7,IL5,TLR2,DLAT,EP300,SQSTM1,PPARG,SYK,SF3A1,IL2RG,CBX5,JAK2,ESR2,NMI,SRC,STAT1,STAT5A,FBXO22,CSNK2B,BRCA1,ZNF596,PTPN11,IL2RB,FLOT1,KIT,JAK1,CYP2C9,CCR5,GHR,CRKL,CTLA4,PDHA1,MDM2,PGR,SPPL3,AQP11,KLHL7,PTPN1,CBL,CD247,SHC1,PPIB,NOL4,NFKB1 |
| 2.433e-02 | -3.72 | CCDC85C (coiled-coil domain containing 85C) | protein interactions | 317762 | 123 | 45 | 19454 | 5460 |
GGPS1,VIRMA,RPGRIP1L,ACTB,ANAPC2,PHF21A,CTNNA1,BICD2,YWHAZ,SAYSD1,PPP1CC,KDM1A,APPBP2,P4HA2,SQSTM1,SCLT1,CRYAB,WWP1,FGFR1,PPP1CB,CDC42,ATG16L1,ING5,CNTROB,EGLN3,HNRNPL,CD4,CEBPG,SSX2IP,YWHAB,YWHAH,CPEB1,YWHAG,XPO1,INSYN1,CTNNB1,NDC80,WWP2,FLOT1,KDM4B,SCPEP1,FAM168A,RND3,SKA3,PNMA2 |
| 2.433e-02 | -3.72 | MAST3 (microtubule associated serine/threonine kinase 3) | protein interactions | 23031 | 123 | 45 | 19454 | 5460 |
EIF2S2,CSNK2B,RTRAF,POLR2F,PTEN,ATP5F1B,FAM110B,CUL3,MAP3K21,DEPDC1B,PPP1CC,YWHAZ,FBXW11,CALU,PYM1,RTKN,XRCC5,FAM53C,DDX5,HNRNPA0,HSPA5,PRKAB1,INPP5E,SIPA1L1,LMNA,AGAP1,EIF4E2,EIF2S1,KCTD3,SAV1,CSNK2A1,YWHAG,YWHAH,TIAM1,RB1CC1,YWHAB,DRG1,CAMSAP2,TESK2,SRSF12,KIF1C,TULP3,PRKAG1,PNMA2,STARD13 |
| 2.433e-02 | -3.72 | RBM26 (RNA binding motif protein 26) | protein interactions | 64062 | 123 | 45 | 19454 | 5460 |
DDRGK1,HNRNPA1,XPO1,VPS26A,H2AC4,SNRNP70,DDX23,STX5,RB1,WIF1,THOC1,PRNP,FZR1,HINFP,RAF1,CERK,SRSF8,RNF26,PAX6,G3BP1,CHCHD2,AR,ANAPC15,OST4,MYC,UBE2H,PEA15,YWHAZ,EIF4A3,CTNNA1,TNPO3,JUNB,ESR2,VIRMA,SRPK2,FBXO22,RNASEH1,ATG16L1,RPA2,NUP50,EP300,BAP1,RPA3,AATF,PSENEN |
| 2.433e-02 | -3.72 | TPST2 (tyrosylprotein sulfotransferase 2) | protein interactions | 8459 | 123 | 45 | 19454 | 5460 |
DUSP14,TRAM1,TMEM106A,SEC62,EIF2B3,PLAA,CHRNB2,SLC39A9,MIS12,CLEC12B,TPST1,SLC7A1,RNF5,STX7,DSN1,TOMM40,CSGALNACT2,ATP1A3,CCR2,TNPO3,IPO8,TOP3B,SPC24,DDX39A,TMEM59,CCR1,VAC14,TMED1,ATP2B4,CCR5,CSE1L,ERLEC1,NDC80,CMKLR2,KLHL9,GOLPH3L,CAMLG,MCOLN1,NRSN1,RAP1B,EIF2B5,ATXN10,EIF2B2,NUF2,RMND1 |
| 2.435e-02 | -3.72 | glucan metabolic process | biological process | GO:0044042 | 62 | 26 | 18204 | 5365 |
LEPR,WDR45,PPP1R2,PYGB,GYS1,PHKG1,IL6ST,GABARAPL1,PPP1CC,GNMT,PPP1R1A,GSK3A,PPP1R3C,AKT1,GBE1,PYGM,PHKB,ATG3,AKT2,PTGES3,PHKA1,PPP1CB,RB1CC1,UGP2,STBD1,COMT |
| 2.435e-02 | -3.72 | positive regulation of interleukin-1 beta production | biological process | GO:0032731 | 62 | 26 | 18204 | 5365 |
MIR206,NLRP3,MYD88,NLRP1,CCL3,AGER,PYCARD,TLR4,IFI16,TLR8,LILRA2,CCL19,TLR6,EGR1,SMAD3,IFNG,MIR144,TYROBP,TNF,JAK2,TMEM106A,HSPB1,NLRP2,IL6,CLEC7A,CD36 |
| 2.437e-02 | -3.71 | recycling endosome membrane | cellular component | GO:0055038 | 107 | 41 | 19108 | 5553 |
VAMP3,GRIA1,RAP2C,CLIP3,INPP4A,CMTM6,EHD3,RAB8B,SCAMP5,STX6,VAMP8,STX12,RAB11B,SLC31A1,PDLIM4,NSG1,ARF6,CFTR,LAMP5,TFRC,RAB35,EHD4,SLC11A2,CD274,RAP2A,SNX18,SCAMP2,B2M,RAB11A,RAB13,RAP2B,ABHD17A,OPTN,RAB14,EHD1,SLC1A1,PDIA3,ATG9A,BOK,VTI1B,RAB4A |
| 2.443e-02 | -3.71 | XTALbg | smart domains | SM00247 | 15 | 8 | 9717 | 2575 |
CRYGD,CRYBB2,CRYBA4,CRYBB3,CRYGA,CRYGB,CRYBA1,CRYBA2 |
| 2.445e-02 | -3.71 | nucleosomal DNA binding | molecular function | GO:0031492 | 64 | 27 | 18094 | 5411 |
RBBP4,H2AZ2,H2AB1,H2AJ,H2AC13,ACTL6A,MACROH2A2,H2AC25,SMARCB1,H2AC6,H1-1,H1-3,H2AX,H2AC4,H2AZ1,ACTB,SMARCE1,H1-5,HNRNPC,H1-6,MACROH2A1,H2AC1,H2AC7,HMGN4,MBD3,MTA2,H1-10 |
| 2.452e-02 | -3.71 | OTX2 (orthodenticle homeobox 2) | protein interactions | 5015 | 56 | 23 | 19454 | 5460 |
ZNHIT1,CDK4,TBCEL,TNPO2,KLF3,HIKESHI,SMARCB1,OTX2,SNRPA,DDX46,EIF4E,ZDHHC17,POLDIP3,NAA50,HNF1B,JPT1,TMEM11,POU5F1,RPS26,HOMER3,TRMT10B,GTF2F2,MITF |
| 2.452e-02 | -3.71 | DNAJC4 (DnaJ heat shock protein family (Hsp40) member C4) | protein interactions | 3338 | 56 | 23 | 19454 | 5460 |
MRPS18B,TXNL1,CLPB,DLAT,GRPEL1,MRPS7,EXOSC8,MTX2,NDUFA5,MRPS9,COX4I1,DLST,MAT2B,CHCHD3,MRPS23,APEX1,MTPN,PDIA3,PYCR2,COX5A,MRPS35,HAX1,MRPS26 |
| 2.452e-02 | -3.71 | RAB3IL1 (RAB3A interacting protein like 1) | protein interactions | 5866 | 56 | 23 | 19454 | 5460 |
ATG4C,TIGD7,TRAPPC1,PSMA3,CTDSP1,EIF1AX,GPX1,IP6K1,MB21D2,SPPL3,CYRIB,OPTN,NUDT18,TRAPPC3,TRAPPC10,PPFIA3,TRAPPC2L,RAB3A,STX1A,TRAPPC4,EXOC8,RAB11A,PPIL4 |
| 2.452e-02 | -3.71 | HTR6 (5-hydroxytryptamine receptor 6) | protein interactions | 3362 | 56 | 23 | 19454 | 5460 |
CDK5,NCDN,MAP1B,IPO8,GNAQ,AKR1A1,SCHIP1,THY1,AP2M1,EIF4A3,DNM2,AIP,ATXN10,ACTB,RANBP6,DDRGK1,COPS5,CMSS1,SLC6A1,DHRS1,XPOT,EXOC2,NOVA1 |
| 2.452e-02 | -3.71 | FOXD4 (forkhead box D4) | protein interactions | 2298 | 56 | 23 | 19454 | 5460 |
PSMG4,HSPA8,DLAT,AHCYL1,PDHB,EIF5B,CHCHD2,PPP2R1A,TUBA1A,GSTP1,PPP4C,CRYAB,PDHA1,TACO1,PPP2CB,GGPS1,KIAA0232,RNASEH1,TUBB,TRIM29,MDFI,AKAP8L,PSMG3 |
| 2.452e-02 | -3.71 | TLK1 (tousled like kinase 1) | protein interactions | 9874 | 56 | 23 | 19454 | 5460 |
H1-1,LHX2,HLF,GPRASP3,TPM3,PTPN11,HNRNPL,SNRNP40,DYNLL1,ABHD14B,ZNF655,TFCP2,PPP1CB,TOP3B,PAX6,H3C1,ASF1A,DDIT3,SNAP23,YAF2,HIRA,PML,NBN |
| 2.452e-02 | -3.71 | CNOT6 (CCR4-NOT transcription complex subunit 6) | protein interactions | 57472 | 56 | 23 | 19454 | 5460 |
GARRE1,LSM14A,PABPC1,ZC3H7A,CNOT7,CAPZA1,RIGI,CNOT6L,YTHDF2,TNRC6C,MAP1LC3B,CAPZA2,RPA2,IZUMO1,CNOT6,FANCD2OS,EGLN3,CNOT2,NFKB1,ZMAT3,CNOT8,GADD45B,HSP90AA1 |
| 2.452e-02 | -3.71 | NECAP2 (NECAP endocytosis associated 2) | protein interactions | 55707 | 56 | 23 | 19454 | 5460 |
AP2S1,SCLT1,FGFR1,NECAP1,RPA2,TRAF2,AP1M1,ARF4,STAU1,GHRL,HSPA8,FBXO11,RPA3,INPPL1,PLSCR1,DVL2,AP2A1,GLOD4,NMI,PRNP,DYNC1I2,TES,AP2M1 |
| 2.452e-02 | -3.71 | DLC1 (DLC1 Rho GTPase activating protein) | protein interactions | 10395 | 56 | 23 | 19454 | 5460 |
ZNF189,PTEN,S100A10,FBXW7,FZR1,TRMO,CAV1,SFRP4,CUL2,CUL3,AKT1,FEM1B,PPP3R2,SMAD1,UTP6,YWHAG,HSD17B3,STX17,TDRD7,FBP2,STARD13,TMOD1,LACC1 |
| 2.452e-02 | -3.71 | CHFR (checkpoint with forkhead and ring finger domains) | protein interactions | 55743 | 56 | 23 | 19454 | 5460 |
PML,PCNA,CDK5,UBE2D3,GABBR1,EEF1G,RIGI,UBE2W,RNF7,SMARCB1,RNF126,SIN3A,UBE2N,UBE2I,CDC20,MAD2L1,APEX1,AKT1,GRB10,UBE2E2,CUL3,UBE2D1,UBE2E3 |
| 2.452e-02 | -3.71 | SLC38A7 (solute carrier family 38 member 7) | protein interactions | 55238 | 86 | 33 | 19454 | 5460 |
LAMP2,OPRM1,SCN3B,LAMTOR2,SLC38A9,ACTL6B,LAMTOR1,CYB561,FCER1G,AQP2,SLC23A2,SSMEM1,CYB5R3,AMIGO1,ATP6V1A,LAMTOR3,LY6G6C,TMEM237,PDCD1LG2,CFTR,ETF1,LMNA,CA14,CRELD1,PLD3,SLC22A6,TCEA1,ERP29,KRAS,RNF5,APH1A,VRK1,PDE2A |
| 2.452e-02 | -3.71 | NCEH1 (neutral cholesterol ester hydrolase 1) | protein interactions | 57552 | 86 | 33 | 19454 | 5460 |
ASIC1,CD151,SELENON,OS9,ABHD12,FAM177A1,CD1E,AMIGO1,DIPK2A,TMEM106C,ATP1A3,BTN2A2,IGF2BP1,EDEM1,ST6GALNAC3,FAM20C,HMOX2,CLEC12B,HSPA5,UQCC3,TMEM106B,C1QL1,LRRC3,EZH2,ZNRF1,NRN1,CYB5B,TMEM231,CFTR,HYAL2,DIPK1A,HCST,SEC62 |
| 2.452e-02 | -3.71 | TNFSF9 (TNF superfamily member 9) | protein interactions | 8744 | 86 | 33 | 19454 | 5460 |
TNFSF18,TRAF1,LILRB4,NRSN1,FUT1,TNFRSF9,CD226,NCR3LG1,FCGR1A,SCN3B,VAMP5,ICAM2,PLPP4,CD200R1,ICOS,DDRGK1,CD1B,TNFSF8,TNF,CLU,RUSF1,TLR4,LRRN4CL,SFTPC,RARRES2,CTLA4,GPX7,SIGLECL1,IL20RB,PDCD1LG2,TRAF2,TMEM59,TIRAP |
| 2.452e-02 | -3.71 | EGLN1 (egl-9 family hypoxia inducible factor 1) | protein interactions | 54583 | 86 | 33 | 19454 | 5460 |
TBK1,APOBEC3C,POLR2C,OXSR1,AKT2,DVL2,PRPSAP1,AKAP1,ERP29,IGF1R,H3C1,KRAS,STAU1,FKBP8,PTGES3,AKT1,CUL3,BTF3,RHOBTB3,SIAH2,SPOP,TAFAZZIN,FKBP4,NTRK3,HSP90AA1,RMDN3,SPPL3,ARF6,CITED1,EGLN3,HSP90AB1,SRC,OS9 |
| 2.452e-02 | -3.71 | HLA-F (major histocompatibility complex, class I, F) | protein interactions | 3134 | 86 | 33 | 19454 | 5460 |
CFC1,DPP4,TAFAZZIN,SDF2L1,NTRK3,TMEM30A,CHRM5,GXYLT1,ST8SIA5,ELSPBP1,DNASE1L1,FUT1,ADAM21,DUOXA2,CD1A,GINM1,BRINP1,CFTR,CBLN4,LILRB1,TMEM106A,CLEC2B,AQP3,SFTPC,CA14,OGFOD3,CST11,GPIHBP1,CD1B,ST8SIA4,CLEC12B,GREM2,B2M |
| 2.452e-02 | -3.71 | LIN54 (lin-54 DREAM MuvB core complex component) | protein interactions | 132660 | 86 | 33 | 19454 | 5460 |
LHX2,TFDP2,AR,OST4,MYC,HNF1B,APEX1,MAD2L1,RBBP4,SPPL3,RB1,SPINT2,ZMYM2,MYBL2,ELK3,GSTO2,PSMC3,RPA2,KLF3,CBX3,ELF1,IKZF5,KLF12,SOX2,TP53,E2F4,PAX6,TUSC3,ASF1A,B9D2,SLC31A1,PML,RPA3 |
| 2.452e-02 | -3.71 | DHRS4 (dehydrogenase/reductase 4) | protein interactions | 10901 | 86 | 33 | 19454 | 5460 |
PRELP,POLDIP2,CHCHD2,PDE12,NDUFS2,ATP5F1D,CST11,ATP5F1E,CLPB,DHRS3,SLC25A3,NDUFA5,AQP3,NDUFS3,PDHA1,DHRS4,GLRX5,PRDX3,NDUFAF3,FBP1,EHHADH,HEXA,TP53,ESR2,MRPL13,FAHD1,BOLA1,LY6G5C,SPOP,TMEM70,PCCB,LMO2,PMPCA |
| 2.453e-02 | -3.71 | transcription factor TFIIK complex | cellular component | GO:0070985 | 3 | 3 | 19108 | 5553 |
CCNH,CDK7,MNAT1 |
| 2.453e-02 | -3.71 | U2-type post-mRNA release spliceosomal complex | cellular component | GO:0071008 | 3 | 3 | 19108 | 5553 |
TFIP11,DHX15,GCFC2 |
| 2.453e-02 | -3.71 | U4/U6 snRNP | cellular component | GO:0071001 | 3 | 3 | 19108 | 5553 |
SART3,PRPF4,PPIH |
| 2.453e-02 | -3.71 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex | cellular component | GO:0070033 | 3 | 3 | 19108 | 5553 |
CPLX2,SNAP25,VAMP2 |
| 2.453e-02 | -3.71 | ciliary pocket membrane | cellular component | GO:0020018 | 3 | 3 | 19108 | 5553 |
EHD3,EHD1,SNAP29 |
| 2.453e-02 | -3.71 | 1-alkyl-2-acetylglycerophosphocholine esterase complex | cellular component | GO:0008247 | 3 | 3 | 19108 | 5553 |
PAFAH1B3,PAFAH1B2,PAFAH1B1 |
| 2.453e-02 | -3.71 | ISGF3 complex | cellular component | GO:0070721 | 3 | 3 | 19108 | 5553 |
STAT1,IRF9,STAT2 |
| 2.453e-02 | -3.71 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex | cellular component | GO:0070032 | 3 | 3 | 19108 | 5553 |
SNAP25,VAMP2,SNAP23 |
| 2.453e-02 | -3.71 | Mpp10 complex | cellular component | GO:0034457 | 3 | 3 | 19108 | 5553 |
IMP3,MPHOSPH10,IMP4 |
| 2.453e-02 | -3.71 | ciliary pocket | cellular component | GO:0020016 | 3 | 3 | 19108 | 5553 |
EHD1,SNAP29,EHD3 |
| 2.453e-02 | -3.71 | cyclin-dependent protein kinase activating kinase holoenzyme complex | cellular component | GO:0019907 | 3 | 3 | 19108 | 5553 |
CDK7,MNAT1,CCNH |
| 2.458e-02 | -3.71 | HK3 (hexokinase 3) | protein interactions | 3101 | 33 | 15 | 19454 | 5460 |
PTGDS,PPP2CB,NPC2,RIGI,FUNDC2,MITF,ZBTB17,SEC22C,ATF4,INPP4A,HPGDS,SDR16C5,IGFBP4,AGPAT1,LEP |
| 2.458e-02 | -3.71 | GPATCH2 (G-patch domain containing 2) | protein interactions | 55105 | 33 | 15 | 19454 | 5460 |
XPO1,CSNK2A1,DPY30,RAF1,TSNAX,LRP6,PSMD14,KCNJ10,SYT2,CSNK2B,PICK1,EGLN3,FGF12,HNRNPL,COPE |
| 2.458e-02 | -3.71 | Ercc6l (excision repair cross-complementing rodent repair deficiency complementation group 6 like) | protein interactions | 236930 | 33 | 15 | 19454 | 5460 |
SSBP1,UQCRC2,NDUFB4,ATP5PD,RPL17,NOP9,RPF1,YIPF5,RMI2,KDSR,ATP5MG,RMI1,MRPL18,TIMM23,ZNHIT3 |
| 2.458e-02 | -3.71 | ASPHD2 (aspartate beta-hydroxylase domain containing 2) | protein interactions | 57168 | 33 | 15 | 19454 | 5460 |
FAM20B,CLEC2B,DLK2,FAM174A,ST3GAL2,ST3GAL1,CHRNB2,IZUMO1,SPINT2,TAS1R2,ADAM21,GXYLT1,B4GALT3,CD1B,GRPR |
| 2.458e-02 | -3.71 | PPM1K (protein phosphatase, Mg2+/Mn2+ dependent 1K) | protein interactions | 152926 | 33 | 15 | 19454 | 5460 |
NTAQ1,PMPCA,PPM1K,CHCHD1,NME2,CDK8,MRPL13,HSPB2,BIRC2,BCKDK,PTK7,IDE,DBT,LDHA,HNRNPL |
| 2.458e-02 | -3.71 | KATNAL1 (katanin catalytic subunit A1 like 1) | protein interactions | 84056 | 33 | 15 | 19454 | 5460 |
RIGI,PFDN1,FKBP2,FBXW7,SIAH1,HNRNPL,COX17,CEP57L1,KATNAL1,S100A6,DISC1,VPS4B,GCC1,CCT2,CFTR |
| 2.458e-02 | -3.71 | Sin3a (transcriptional regulator, SIN3A (yeast)) | protein interactions | 20466 | 33 | 15 | 19454 | 5460 |
SNAI2,MXD1,SAP30,BRMS1,SNAI3,ING1,TP53,ELK1,SAP18,BRMS1L,KLF1,RBBP7,COPS2,RB1,SMAD3 |
| 2.458e-02 | -3.71 | GTF2H5 (general transcription factor IIH subunit 5) | protein interactions | 404672 | 33 | 15 | 19454 | 5460 |
CCNH,RNF40,GTF2E1,CDK7,ERCC3,GTF2H4,CETN2,MNAT1,PPP1R2,STAU1,CDC7,CDCA3,GTF2H2,GTF2F1,NGRN |
| 2.458e-02 | -3.71 | CNGA3 (cyclic nucleotide gated channel subunit alpha 3) | protein interactions | 1261 | 33 | 15 | 19454 | 5460 |
ABCB9,TMX2,SEMG2,STX5,TRIM54,COMMD3,ZMYM3,ZMYM4,SNX14,MUL1,RAB6B,CCDC22,ESYT1,C2CD2L,ADCY3 |
| 2.458e-02 | -3.71 | WDR89 (WD repeat domain 89) | protein interactions | 112840 | 33 | 15 | 19454 | 5460 |
RPL10A,ANKRD49,SPOP,CCT2,APOBEC3C,XPO1,HMGA1,WWP2,ESR2,RPL22,POLR3F,RPL13A,RPL3,FGFBP1,PHYHIP |
| 2.458e-02 | -3.71 | NUDT1 (nudix hydrolase 1) | protein interactions | 4521 | 33 | 15 | 19454 | 5460 |
CAND1,RRAGB,SPPL3,DCUN1D1,NAPG,DYRK1A,APEX1,CCNF,FAM91A1,SPIN3,HSPA8,GP9,CUL2,CFTR,COPS5 |
| 2.458e-02 | -3.71 | KRTCAP3 (keratinocyte associated protein 3) | protein interactions | 200634 | 33 | 15 | 19454 | 5460 |
VAMP3,TSPAN15,ADGRL3,GOSR1,CD47,FNDC9,MSMO1,FUT8,GOSR2,GOLPH3L,TMX4,GOLGA5,REEP6,FITM2,TSPAN3 |
| 2.467e-02 | -3.70 | positive regulation of secretion | biological process | GO:0051047 | 311 | 108 | 18204 | 5365 |
LACRT,RETN,OXTR,VAMP7,RAB3D,AVPR1B,KLRC2,OSBP,IL1A,TGFB2,APBB3,IGF1,PFKFB2,SELENOT,SMAD4,S100A8,S100A10,VPS4B,NKX3-1,TGFB3,CDK5,GOLPH3L,IL1B,SPP1,STX1A,HFE,VAMP8,CXCL12,PPP3CA,SLC6A1,RAB27A,GNA11,SRI,BAD,SLC4A8,HGS,PRKCB,CHRM3,PRKCE,NR1H2,SPHK2,SYBU,TSG101,JAK2,STXBP1,OR51E2,MAP2K6,RAB3A,CARTPT,F2,ARF6,C2CD2L,SLC12A2,NLGN2,RAB5A,TLR2,GHRL,XBP1,CD38,CFTR,CD2AP,IL13,PTGES,BGLAP,PPIA,VPS4A,CREB1,RAB8B,IFNG,NLGN1,FGR,ACSL4,DYNLL1,KCNB1,SDC4,SDCBP,LEP,LRRC8A,SNAP25,PARD6A,VEGFC,TLR4,PTPN11,SCAMP5,PPID,ADORA1,MIF,RASL10B,RAB9A,PRL,P2RY1,FGFR1,GABBR1,CHRNB2,UCN,C1QTNF1,SLC6A4,ACHE,CHMP2A,INHA,SYT4,PPARG,OPRK1,RGCC,TACR1,ILDR1,PLCB1,PCK2 |
| 2.471e-02 | -3.70 | BACH2 (BTB domain and CNC homolog 2) | protein interactions | 60468 | 83 | 32 | 19454 | 5460 |
SCNM1,RPL9,CYTH1,PSMC5,ZBTB17,HMG20A,RPP25,CUL3,CENPP,KLHL9,FOSL2,BAHD1,KLHL25,TCEA2,KLHL24,MAEA,DDIT3,BACH1,HDAC3,ZBTB45,BCL6,AP1M1,FAM161A,CSNK1E,TULP3,NFE2L1,MAFG,JUN,INSYN2A,IPP,ENC1,MTA2 |
| 2.473e-02 | -3.70 | BCOR (BCL6 corepressor) | protein interactions | 54880 | 290 | 97 | 19454 | 5460 |
IRF4,ELOC,HDAC6,CSNK2A1,MIF,CPNE1,PTPN1,H2AZ1,ARPC3,CBX3,PHC1,OTX2,IPO8,TP53,H2AX,EGR2,KPNA2,PQBP1,RING1,CPNE2,NAA50,CDC16,SUGP1,KPNA6,AR,TIA1,VIRMA,TECR,PHAX,CSNK2B,TRIM27,QSER1,ZNF326,RPA2,E2F6,PAX9,RBFOX2,KLF12,KDELR2,SMC4,SGF29,HDAC3,BCL6,MBD3,PML,RPA3,BAP1,ARL14EP,AK2,LHX2,DPY30,HMGA1,EIF3D,TCP1,CCAR2,NOP58,HMG20A,NUP35,EGLN3,FUBP3,EED,MTA2,SOX2,TUBA1A,CBX7,ASF1A,TRIM37,PCGF3,HNRNPF,ZNF609,PAX6,PCGF6,HSPD1,BAG2,FBXW11,SP1,MYC,HNF1B,ATG101,RBBP4,SNRNP40,CBX5,UBTD1,ELK3,PHF21A,KLF3,CTBP1,RADX,B9D2,PRCP,SKP1,COIL,ZBTB5,NUP50,YAF2,PCGF2,HDAC5 |
| 2.475e-02 | -3.70 | regulation of regulatory T cell differentiation | biological process | GO:0045589 | 37 | 17 | 18204 | 5365 |
IFNG,BCL6,FOXP3,IRF1,VSIR,CTLA4,KLHL25,IL2RG,DROSHA,DUSP10,LILRB4,MIR21,MIR30B,CD28,IL2,BTN2A2,CD46 |
| 2.475e-02 | -3.70 | negative regulation of lymphocyte apoptotic process | biological process | GO:0070229 | 37 | 17 | 18204 | 5365 |
SLC39A10,BCL6,IDO1,BCL10,PRKCQ,FOXP1,ORMDL3,CCL5,MIF,PTCRA,ST3GAL1,TSC22D3,GPAM,ARG2,RAG1,IL2,PDCD1 |
| 2.475e-02 | -3.70 | positive regulation of response to endoplasmic reticulum stress | biological process | GO:1905898 | 37 | 17 | 18204 | 5365 |
CAV1,STUB1,NFE2L2,XBP1,USP13,PIK3R1,TMEM33,BOK,PTPN1,SERINC3,AGR2,BAK1,FCGR2B,BAX,PMAIP1,NCK1,SGTA |
| 2.475e-02 | -3.70 | positive regulation of heart contraction | biological process | GO:0045823 | 37 | 17 | 18204 | 5365 |
TGFB2,ADRA1A,SCN3B,APLN,RGS2,ADM2,ATP1A2,TACR3,UCN,SLC1A1,HEY2,ATP1A1,CHGA,HSP90AA1,ADRB1,GSK3A,MIR1-1 |
| 2.475e-02 | -3.70 | FHL1 (four and a half LIM domains 1) | protein interactions | 2273 | 120 | 44 | 19454 | 5460 |
EED,SMAD3,PRNP,DDRGK1,USP15,SMAD4,RING1,EWSR1,TRIM21,MDC1,AKAP12,G3BP1,KBTBD4,SOD2,RBPJ,CMBL,ENO1,FERMT2,SMURF1,GNB1,SRC,PDLIM3,AKT1,CREBBP,CUL3,SFN,RAB11A,SMAD2,SP1,UBE2H,BICD2,TXNIP,YWHAZ,HSPA8,EP300,RPA3,BAP1,NFIL3,STAU1,NEK7,CFTR,SF3A1,RPA2,LMNA |
| 2.476e-02 | -3.70 | ionotropic glutamate receptor binding | molecular function | GO:0035255 | 26 | 13 | 18094 | 5411 |
FLOT1,SQSTM1,CDK5R1,DLG4,SDCBP,NSG1,DLG1,IGSF11,CACNG3,NETO1,DLG3,OPHN1,NETO2 |
| 2.477e-02 | -3.70 | positive regulation of receptor signaling pathway via STAT | biological process | GO:1904894 | 48 | 21 | 18204 | 5365 |
ADIPOR1,LEP,MIR221,IL6,F2,VEGFA,GH1,IL4,IL10,KIT,CYP1B1,OCIAD2,GHR,CCL5,TNF,CRLF3,CSH1,JAK2,IL5,PRL,EP300 |
| 2.477e-02 | -3.70 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902041 | 48 | 21 | 18204 | 5365 |
TMBIM1,RNF34,GPX1,STK3,PMAIP1,ATF3,FAF1,TNFAIP3,SFRP1,MIR221,ICAM1,RAF1,STK4,BRCA1,MIR222,FEM1B,FAIM,BMPR1B,LGALS3,BCL2L1,PEA15 |
| 2.477e-02 | -3.70 | regulation of calcium ion import | biological process | GO:0090279 | 48 | 21 | 18204 | 5365 |
MIR34A,TRIM27,CAV3,HOMER1,UCN,PRNP,CTNNB1,MIR208B,SPHK2,CXCL12,MIR208A,CASK,PLPP4,STC1,LGALS3,MIR200C,PPP3R2,CCL2,PPP3CA,CCL3,PLN |
| 2.479e-02 | -3.70 | MBLAC2 (metallo-beta-lactamase domain containing 2) | protein interactions | 153364 | 59 | 24 | 19454 | 5460 |
CD226,BZW2,AGTRAP,MARCHF5,FLRT3,BCS1L,CNNM4,BLOC1S3,MANSC1,SPCS1,GRPR,CD1B,ASIC1,HNRNPL,F11R,ACP2,SLC5A6,RAMP3,DUSP21,DUSP6,CD63,DUSP9,NAP1L5,IL2RA |
| 2.479e-02 | -3.70 | S100A3 (S100 calcium binding protein A3) | protein interactions | 6274 | 59 | 24 | 19454 | 5460 |
S100A10,TGIF2LX,FBXL4,TFG,FBXO3,THNSL1,FOS,SEMG2,CAPZA2,SKA2,SGIP1,DLG3,KDELR2,VTI1B,RAB11B,RAB9B,OR51E2,SYP,CSGALNACT1,NAA50,AKT1,AKT3,PTDSS1,ISCA2 |
| 2.479e-02 | -3.70 | ELOA2 (elongin A2) | protein interactions | 51224 | 59 | 24 | 19454 | 5460 |
TRAF2,SERPINA3,JCHAIN,SERPINA1,SREK1IP1,LCP1,DVL2,MAEA,THNSL1,NKAPD1,GCA,COIL,RANBP10,TRIM37,ELOC,CEP70,ZMYND19,KXD1,ZCCHC10,LYZ,SERPINB1,DCAF5,CDK6,CBX5 |
| 2.479e-02 | -3.70 | ZNF462 (zinc finger protein 462) | protein interactions | 58499 | 59 | 24 | 19454 | 5460 |
CBX3,EZH2,TULP3,CFTR,EGR2,SOX2,RBBP7,ABHD10,PAX6,COIL,TCOF1,RUVBL2,CALU,AR,FBXO7,SNRNP40,RBBP4,HYPK,HNRNPL,VIRMA,ANKRA2,CBX5,AIFM1,ZMYM2 |
| 2.479e-02 | -3.70 | CCDC50 (coiled-coil domain containing 50) | protein interactions | 152137 | 59 | 24 | 19454 | 5460 |
HSPA5,RIGI,OIP5,MAVS,IGF1R,HADHA,SQSTM1,ARRDC3,EWSR1,PML,TYW5,RNF8,NUPR1,MAP1LC3B,IL1R2,TANK,TES,NRSN1,RCHY1,BICD2,ARHGAP19,PPIB,IFIH1,TNFAIP3 |
| 2.479e-02 | -3.70 | GRAMD4 (GRAM domain containing 4) | protein interactions | 23151 | 59 | 24 | 19454 | 5460 |
RPN1,RPSA,SEC62,OTULINL,CDK7,RBMS2,SLC25A11,SRSF7,NOA1,DNAJC10,EXOC8,PRDX1,NTAQ1,SPPL3,PLEKHF2,DKC1,GADD45G,SYNCRIP,SSBP1,PRR3,HSD17B11,GNAO1,PHAX,SEC61B |
| 2.479e-02 | -3.70 | MAPK10 (mitogen-activated protein kinase 10) | protein interactions | 5602 | 59 | 24 | 19454 | 5460 |
STMN2,TP53,MAPK10,DUSP1,JUN,HNRNPK,DDI1,DUSP9,CDKN2C,CDK5,DDX5,UBE3A,CCT2,CDKN1B,HAX1,CREBBP,FBXO7,LDHA,ELK1,CCT7,DUSP10,HRAS,MCL1,MSN |
| 2.479e-02 | -3.70 | TCL1A (TCL1 family AKT coactivator A) | protein interactions | 8115 | 59 | 24 | 19454 | 5460 |
ODR4,TNKS,METAP1,NFKBIA,TRMT61A,TRAF1,JUNB,TAX1BP1,NTAQ1,TTC33,AKT1,AKT3,ANAPC4,LSM3,NIF3L1,EP300,AKT2,H2AC25,KLHL24,FOS,TRAF2,JUN,LNX2,DDIT4L |
| 2.479e-02 | -3.70 | CAVIN2 (caveolae associated protein 2) | protein interactions | 8436 | 59 | 24 | 19454 | 5460 |
TP53,WBP11,NUPR1,TRAPPC6A,PRKCA,TCOF1,DVL2,MAP1B,RTN4,RPL23A,THRAP3,SSRP1,MDC1,MOV10,H2AC14,CD9,NUDT18,COPS2,MACROH2A1,TRIM54,PLEKHF2,CAVIN2,PLEKHF1,SRPK2 |
| 2.479e-02 | -3.70 | PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2) | protein interactions | 9060 | 59 | 24 | 19454 | 5460 |
CEP19,APEX1,KCTD10,DAPK1,SNX17,EFHD2,WDR6,HNRNPD,DNAJC7,AGR2,GMPS,ATP5F1A,PTPN11,MYC,FBXW7,RNF115,HNRNPA2B1,RBM3,HECTD1,GDI2,MAP2K1,GGCT,GTF3C4,TXNRD1 |
| 2.479e-02 | -3.70 | UVRAG (UV radiation resistance associated) | protein interactions | 7405 | 59 | 24 | 19454 | 5460 |
APEX1,SMURF1,POLR3F,POLR2F,POLR3B,YWHAB,BAX,BECN1,YWHAZ,BLVRA,ATG101,YWHAH,XPO1,YWHAG,ATG9A,RALB,VPS39,VPS16,NUBP2,HECTD1,CSNK1A1,VPS18,VPS33A,TOP3B |
| 2.485e-02 | -3.70 | carbohydrate derivative transport | biological process | GO:1901264 | 91 | 36 | 18204 | 5365 |
SLC25A4,SLC25A24,GJB1,ANKH,SLC35C1,SLC25A17,NPC2,SLC25A5,G6PC3,SLC35A1,LRRC8D,PLEKHA8,CPTP,ABCC5,GLTP,CD47,SLC35B3,VLDLR,SLC25A42,SLC25A26,SLC35A5,SLC35D1,SLC29A1,SLC35A2,LRRC8C,LRRC8B,SLC25A23,SLC15A2,SHOC2,LRRC8A,SLC25A31,SLC35B4,CALHM3,SLC37A4,GUK1,SLC35E3 |
| 2.486e-02 | -3.69 | stomach-carcinoma-undifferentiated_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-undifferentiated_adenocarcinoma | 52 | 22 | 16828 | 4835 |
SMAD4,IDH1,KRAS,PTEN,FGFR1,JAK2,FBXW7,KIT,MET,BRCA1,TP53,STK11,MAP2K1,MSH6,HRAS,SMARCB1,EP300,PIK3CA,PTPN11,AKT1,RB1,CTNNB1 |
| 2.486e-02 | -3.69 | undifferentiated_adenocarcinoma | COSMIC cancer mutations | undifferentiated_adenocarcinoma | 52 | 22 | 16828 | 4835 |
HRAS,MSH6,STK11,MAP2K1,RB1,CTNNB1,PTPN11,AKT1,EP300,PIK3CA,SMARCB1,KRAS,IDH1,SMAD4,MET,KIT,BRCA1,TP53,JAK2,FBXW7,FGFR1,PTEN |
| 2.486e-02 | -3.69 | MAP kinase activation in TLR cascade | REACTOME pathways | R-HSA-450294 | 64 | 28 | 10285 | 3229 |
RPS27A,UBA52,PPP2R1A,UBB,MEF2C,MAP2K1,MAP2K3,IKBKB,DUSP3,SKP1,TRAF6,MEF2A,FBXW11,NFKB1,PPP2CB,JUN,UBE2V1,TAB1,MAPK10,FOS,UBE2N,DUSP6,ATF1,ELK1,TAB2,CREB1,MAPKAPK3,MAP2K6 |
| 2.486e-02 | -3.69 | THIOREDOXIN_1 | prosite domains | PS00194 | 17 | 9 | 12186 | 3388 |
TXNL1,DNAJC10,PDIA3,TMX3,TMX4,PDIA6,TXNDC12,TXN,PDIA2 |
| 2.487e-02 | -3.69 | nucleoside kinase activity | molecular function | GO:0019206 | 9 | 6 | 18094 | 5411 |
UCKL1,UCK1,DCK,CMPK1,UCK2,ADK |
| 2.487e-02 | -3.69 | NADH dehydrogenase activity | molecular function | GO:0003954 | 9 | 6 | 18094 | 5411 |
AIFM1,NDUFS2,NDUFS3,NDUFS8,NDUFV2,NQO1 |
| 2.487e-02 | -3.69 | threonine-type endopeptidase activity | molecular function | GO:0004298 | 9 | 6 | 18094 | 5411 |
PSMB9,PSMB11,PSMB5,PSMB10,PSMB7,PSMB6 |
| 2.487e-02 | -3.69 | KIF20B (kinesin family member 20B) | protein interactions | 9585 | 80 | 31 | 19454 | 5460 |
CRY1,NLE1,RPA3,IMPACT,SAP18,ASF1A,EEF1G,KDM1A,H3C1,H2AJ,METTL14,HSP90B1,CDK1,RPA2,PHF21A,CMBL,OCIAD2,APEX1,VIRMA,ESR2,SLC38A2,HYPK,PRNP,MLF1,MYC,COP1,VCPIP1,DNAJC7,KPNA1,BRCA1,KDM2A |
| 2.487e-02 | -3.69 | WDR20 (WD repeat domain 20) | protein interactions | 91833 | 80 | 31 | 19454 | 5460 |
AR,XPO1,YWHAG,HSPB8,YWHAH,ATG9A,RAB2A,LAMP2,YWHAB,HSP90AA1,YWHAZ,DCAF4,CIRBP,LAMTOR1,USP46,LDLR,SURF2,RPRM,OPTN,APEX1,FERMT2,CX3CL1,TRIM35,TMEM266,UBL4A,ARL15,PDHA1,PNMA2,SYVN1,ZDHHC17,KRAS |
| 2.487e-02 | -3.69 | DUSP3 (dual specificity phosphatase 3) | protein interactions | 1845 | 80 | 31 | 19454 | 5460 |
TUFM,TMBIM6,NT5C2,CPSF2,ARL6IP6,TAX1BP1,PRNP,RPL35A,GPX1,STAT1,DUSP3,ERLIN1,FGF7,EIF2B3,CASK,IFT22,SYK,DUSP14,GTF2E2,ERLIN2,SNRNP27,CARTPT,DUSP1,TMUB2,ETFA,RPIA,HSCB,TMUB1,BNIP3L,RPA3,CCDC32 |
| 2.487e-02 | -3.69 | INTS9 (integrator complex subunit 9) | protein interactions | 55756 | 80 | 31 | 19454 | 5460 |
RPA3,INO80C,KRAS,SEM1,RUVBL1,KPNA2,SSRP1,ACTL6A,SUPT5H,PPP2R1A,SOX2,SAP30,ELP3,MED23,RPA2,CCNF,PPP2CB,INTS10,POLR2F,SNRNP40,TOP1,POLR2I,MED17,POLR2B,CEP19,ESR2,RUNX1,GAPDH,TXNIP,KPNA1,RIT1 |
| 2.495e-02 | -3.69 | BOMBESINR | prints domains | PR00358 | 3 | 3 | 5227 | 1528 |
GRPR,BRS3,NMBR |
| 2.495e-02 | -3.69 | ADSPHPHTASEB | prints domains | PR01910 | 3 | 3 | 5227 | 1528 |
DUSP21,DUSP14,DUSP18 |
| 2.495e-02 | -3.69 | ODADCRBXLASE | prints domains | PR01179 | 3 | 3 | 5227 | 1528 |
ODC1,AZIN2,AZIN1 |
| 2.495e-02 | -3.69 | ORNDCRBXLASE | prints domains | PR01182 | 3 | 3 | 5227 | 1528 |
AZIN1,AZIN2,ODC1 |
| 2.495e-02 | -3.69 | CUZNDISMTASE | prints domains | PR00068 | 3 | 3 | 5227 | 1528 |
SOD3,SOD1,CCS |
| 2.495e-02 | -3.69 | SSDNABINDING | prints domains | PR01743 | 3 | 3 | 5227 | 1528 |
SSBP2,SSBP4,SSBP3 |
| 2.495e-02 | -3.69 | PI3KINASEP85 | prints domains | PR00678 | 3 | 3 | 5227 | 1528 |
PIK3R2,PIK3R1,PIK3R3 |
| 2.495e-02 | -3.69 | PGNDSYNTHASE | prints domains | PR01254 | 3 | 3 | 5227 | 1528 |
LCN12,LCN15,PTGDS |
| 2.495e-02 | -3.69 | MYELINPLP | prints domains | PR00214 | 3 | 3 | 5227 | 1528 |
GPM6A,GPM6B,PLP1 |
| 2.495e-02 | -3.69 | NUDIXFAMILY | prints domains | PR00502 | 3 | 3 | 5227 | 1528 |
NUDT5,NUDT18,NUDT1 |
| 2.495e-02 | -3.69 | COFILIN | prints domains | PR00006 | 3 | 3 | 5227 | 1528 |
DSTN,CFL2,CFL1 |
| 2.495e-02 | -3.69 | ACONITASE | prints domains | PR00415 | 3 | 3 | 5227 | 1528 |
ACO1,ACO2,IREB2 |
| 2.497e-02 | -3.69 | SOD_Cu/Zn_/chaperone | interpro domains | IPR024134 | 3 | 3 | 18521 | 5414 |
SOD1,SOD3,CCS |
| 2.497e-02 | -3.69 | NTP_transferase_dom | interpro domains | IPR005835 | 3 | 3 | 18521 | 5414 |
GMPPA,GMPPB,EIF2B3 |
| 2.497e-02 | -3.69 | Thioredoxin/glutathione_Rdtase | interpro domains | IPR006338 | 3 | 3 | 18521 | 5414 |
TXNRD3,TXNRD2,TXNRD1 |
| 2.497e-02 | -3.69 | GADD45 | interpro domains | IPR024824 | 3 | 3 | 18521 | 5414 |
GADD45G,GADD45B,GADD45A |
| 2.497e-02 | -3.69 | Iodothyronine_deiodinase_AS | interpro domains | IPR008261 | 3 | 3 | 18521 | 5414 |
DIO3,DIO2,DIO1 |
| 2.497e-02 | -3.69 | SOD_Cu/Zn_BS | interpro domains | IPR018152 | 3 | 3 | 18521 | 5414 |
SOD3,SOD1,CCS |
| 2.497e-02 | -3.69 | SAM_O-MeTrfase | interpro domains | IPR002935 | 3 | 3 | 18521 | 5414 |
COMTD1,COMT,LRTOMT |
| 2.497e-02 | -3.69 | AIF-1_EF_pair | interpro domains | IPR049025 | 3 | 3 | 18521 | 5414 |
EFHD2,AIF1,AIF1L |
| 2.497e-02 | -3.69 | Ribosomal_uL16_dom | interpro domains | IPR016180 | 3 | 3 | 18521 | 5414 |
RPL10,MRPL16,RPL10L |
| 2.497e-02 | -3.69 | PI3K_P85_iSH2 | interpro domains | IPR032498 | 3 | 3 | 18521 | 5414 |
PIK3R2,PIK3R3,PIK3R1 |
| 2.497e-02 | -3.69 | Ribosomal_uL24_CS | interpro domains | IPR005825 | 3 | 3 | 18521 | 5414 |
RPL26L1,RPL26,MRPL24 |
| 2.497e-02 | -3.69 | SLC35_F1/F2/F6 | interpro domains | IPR009262 | 3 | 3 | 18521 | 5414 |
SLC35F2,SLC35F1,SLC35F6 |
| 2.497e-02 | -3.69 | Vps26-related | interpro domains | IPR028934 | 3 | 3 | 18521 | 5414 |
VPS26C,VPS26A,VPS26B |
| 2.497e-02 | -3.69 | BolA-like_sf | interpro domains | IPR036065 | 3 | 3 | 18521 | 5414 |
BOLA1,BOLA2B,BOLA3 |
| 2.497e-02 | -3.69 | Ribosomal_bS18_sf | interpro domains | IPR036870 | 3 | 3 | 18521 | 5414 |
MRPS18C,MRPS18B,MRPS18A |
| 2.497e-02 | -3.69 | Cortexin | interpro domains | IPR020066 | 3 | 3 | 18521 | 5414 |
CTXN2,CTXN1,CTXN3 |
| 2.497e-02 | -3.69 | TMEM106_N | interpro domains | IPR048511 | 3 | 3 | 18521 | 5414 |
TMEM106C,TMEM106B,TMEM106A |
| 2.497e-02 | -3.69 | DOK4/5/6_PH | interpro domains | IPR037816 | 3 | 3 | 18521 | 5414 |
DOK4,DOK5,DOK6 |
| 2.497e-02 | -3.69 | PI3kinase_P85_cSH2 | interpro domains | IPR035020 | 3 | 3 | 18521 | 5414 |
PIK3R1,PIK3R3,PIK3R2 |
| 2.497e-02 | -3.69 | MiT/TFE_N | interpro domains | IPR031867 | 3 | 3 | 18521 | 5414 |
MITF,TFE3,TFEB |
| 2.497e-02 | -3.69 | GLTP_sf | interpro domains | IPR036497 | 3 | 3 | 18521 | 5414 |
PLEKHA8,GLTP,CPTP |
| 2.497e-02 | -3.69 | Ribosomal_uL24_KOW | interpro domains | IPR041988 | 3 | 3 | 18521 | 5414 |
RPL26,RPL26L1,MRPL24 |
| 2.497e-02 | -3.69 | rRNA-MeTfrase_E | interpro domains | IPR015507 | 3 | 3 | 18521 | 5414 |
FTSJ3,MRM2,FTSJ1 |
| 2.497e-02 | -3.69 | RNA_pol_bsu_protrusion | interpro domains | IPR007644 | 3 | 3 | 18521 | 5414 |
POLR2B,POLR3B,POLR1B |
| 2.497e-02 | -3.69 | RNA_pol_Rpb2_3 | interpro domains | IPR007645 | 3 | 3 | 18521 | 5414 |
POLR2B,POLR3B,POLR1B |
| 2.497e-02 | -3.69 | Caveolin_CS | interpro domains | IPR018361 | 3 | 3 | 18521 | 5414 |
CAV3,CAV2,CAV1 |
| 2.497e-02 | -3.69 | TOM1 | interpro domains | IPR014645 | 3 | 3 | 18521 | 5414 |
TOM1L2,TOM1L1,TOM1 |
| 2.497e-02 | -3.69 | Ribosomal_uL10-like_sf | interpro domains | IPR043141 | 3 | 3 | 18521 | 5414 |
MRPL10,RPLP0,MRTO4 |
| 2.497e-02 | -3.69 | RNA_pol_Rpb2_2 | interpro domains | IPR007642 | 3 | 3 | 18521 | 5414 |
POLR2B,POLR1B,POLR3B |
| 2.497e-02 | -3.69 | Acnase/IPM_dHydase_lsu_aba_1/3 | interpro domains | IPR015931 | 3 | 3 | 18521 | 5414 |
ACO2,IREB2,ACO1 |
| 2.497e-02 | -3.69 | Rep_factorC_C | interpro domains | IPR013748 | 3 | 3 | 18521 | 5414 |
RFC2,RFC4,RFC5 |
| 2.497e-02 | -3.69 | Ribosomal_uL10 | interpro domains | IPR001790 | 3 | 3 | 18521 | 5414 |
RPLP0,MRTO4,MRPL10 |
| 2.497e-02 | -3.69 | Aconitase_4Fe-4S_BS | interpro domains | IPR018136 | 3 | 3 | 18521 | 5414 |
ACO2,IREB2,ACO1 |
| 2.497e-02 | -3.69 | Ribosomal_uL16 | interpro domains | IPR047873 | 3 | 3 | 18521 | 5414 |
MRPL16,RPL10,RPL10L |
| 2.497e-02 | -3.69 | DNA-dir_RNA_pol_su2 | interpro domains | IPR015712 | 3 | 3 | 18521 | 5414 |
POLR2B,POLR1B,POLR3B |
| 2.497e-02 | -3.69 | Atypical_DUSP_subfamB | interpro domains | IPR020420 | 3 | 3 | 18521 | 5414 |
DUSP21,DUSP18,DUSP14 |
| 2.497e-02 | -3.69 | Popeye_prot | interpro domains | IPR006916 | 3 | 3 | 18521 | 5414 |
POPDC2,POPDC3,BVES |
| 2.497e-02 | -3.69 | SOD_Cu_Zn_dom | interpro domains | IPR001424 | 3 | 3 | 18521 | 5414 |
SOD3,SOD1,CCS |
| 2.497e-02 | -3.69 | BolA | interpro domains | IPR002634 | 3 | 3 | 18521 | 5414 |
BOLA1,BOLA2B,BOLA3 |
| 2.497e-02 | -3.69 | Alba-like_dom_sf | interpro domains | IPR036882 | 3 | 3 | 18521 | 5414 |
RPP25L,RPP25,POP7 |
| 2.497e-02 | -3.69 | LSm4/Sm_D1/D3 | interpro domains | IPR027141 | 3 | 3 | 18521 | 5414 |
LSM4,SNRPD3,SNRPD1 |
| 2.497e-02 | -3.69 | CARD_dom | interpro domains | IPR031964 | 3 | 3 | 18521 | 5414 |
IFIH1,MAVS,RIGI |
| 2.497e-02 | -3.69 | Nudix_hydrolase | interpro domains | IPR020476 | 3 | 3 | 18521 | 5414 |
NUDT18,NUDT1,NUDT5 |
| 2.497e-02 | -3.69 | Bombsn_rcpt-like | interpro domains | IPR001556 | 3 | 3 | 18521 | 5414 |
GRPR,NMBR,BRS3 |
| 2.497e-02 | -3.69 | Translocation_assoc_membrane | interpro domains | IPR016447 | 3 | 3 | 18521 | 5414 |
TRAM1,TRAM2,TRAM1L1 |
| 2.497e-02 | -3.69 | Myelin_PLP_CS | interpro domains | IPR018237 | 3 | 3 | 18521 | 5414 |
GPM6A,PLP1,GPM6B |
| 2.497e-02 | -3.69 | ADF/Cofilin | interpro domains | IPR017904 | 3 | 3 | 18521 | 5414 |
DSTN,CFL2,CFL1 |
| 2.497e-02 | -3.69 | Lsm14-like_N | interpro domains | IPR025609 | 3 | 3 | 18521 | 5414 |
EDC3,LSM14A,LSM14B |
| 2.497e-02 | -3.69 | Ribosomal_bS18 | interpro domains | IPR001648 | 3 | 3 | 18521 | 5414 |
MRPS18A,MRPS18B,MRPS18C |
| 2.497e-02 | -3.69 | RNA_pol_RPB2_OB-fold | interpro domains | IPR014724 | 3 | 3 | 18521 | 5414 |
POLR1B,POLR3B,POLR2B |
| 2.497e-02 | -3.69 | TMEM106_C | interpro domains | IPR048509 | 3 | 3 | 18521 | 5414 |
TMEM106C,TMEM106A,TMEM106B |
| 2.497e-02 | -3.69 | ODC_AZ_sf | interpro domains | IPR038581 | 3 | 3 | 18521 | 5414 |
OAZ2,OAZ1,OAZ3 |
| 2.497e-02 | -3.69 | Glycolipid_transfer_prot_dom | interpro domains | IPR014830 | 3 | 3 | 18521 | 5414 |
CPTP,GLTP,PLEKHA8 |
| 2.497e-02 | -3.69 | DNA-dir_RNAP_su2_dom | interpro domains | IPR007120 | 3 | 3 | 18521 | 5414 |
POLR3B,POLR1B,POLR2B |
| 2.497e-02 | -3.69 | SSDP_DNA-bd | interpro domains | IPR008116 | 3 | 3 | 18521 | 5414 |
SSBP2,SSBP4,SSBP3 |
| 2.497e-02 | -3.69 | EDEM1/2/3 | interpro domains | IPR044674 | 3 | 3 | 18521 | 5414 |
EDEM2,EDEM3,EDEM1 |
| 2.497e-02 | -3.69 | DNA-dir_RNAP_su2_hyb_sf | interpro domains | IPR037033 | 3 | 3 | 18521 | 5414 |
POLR2B,POLR1B,POLR3B |
| 2.497e-02 | -3.69 | Caveolin | interpro domains | IPR001612 | 3 | 3 | 18521 | 5414 |
CAV1,CAV2,CAV3 |
| 2.497e-02 | -3.69 | Orn/DAP/Arg_de-COase | interpro domains | IPR000183 | 3 | 3 | 18521 | 5414 |
AZIN1,AZIN2,ODC1 |
| 2.497e-02 | -3.69 | Heat_shock_protein_90_CS | interpro domains | IPR019805 | 3 | 3 | 18521 | 5414 |
HSP90AB1,HSP90B1,HSP90AA1 |
| 2.497e-02 | -3.69 | TMEM106 | interpro domains | IPR009790 | 3 | 3 | 18521 | 5414 |
TMEM106C,TMEM106B,TMEM106A |
| 2.497e-02 | -3.69 | Orn_de-COase | interpro domains | IPR002433 | 3 | 3 | 18521 | 5414 |
ODC1,AZIN2,AZIN1 |
| 2.497e-02 | -3.69 | Acoase/IPM_deHydtase_lsu_aba | interpro domains | IPR001030 | 3 | 3 | 18521 | 5414 |
ACO2,IREB2,ACO1 |
| 2.497e-02 | -3.69 | Myelin_PLP | interpro domains | IPR001614 | 3 | 3 | 18521 | 5414 |
GPM6A,PLP1,GPM6B |
| 2.497e-02 | -3.69 | cAMP_dep_PKI | interpro domains | IPR004171 | 3 | 3 | 18521 | 5414 |
PKIG,PKIB,PKIA |
| 2.497e-02 | -3.69 | RNA_pol_Rpb2_7 | interpro domains | IPR007641 | 3 | 3 | 18521 | 5414 |
POLR2B,POLR3B,POLR1B |
| 2.497e-02 | -3.69 | Iodothyronine_deiodinase | interpro domains | IPR000643 | 3 | 3 | 18521 | 5414 |
DIO1,DIO3,DIO2 |
| 2.497e-02 | -3.69 | Rap2 | interpro domains | IPR041840 | 3 | 3 | 18521 | 5414 |
RAP2A,RAP2B,RAP2C |
| 2.497e-02 | -3.69 | Peroxiredoxin_AhpC-typ | interpro domains | IPR024706 | 3 | 3 | 18521 | 5414 |
PRDX2,PRDX1,PRDX6 |
| 2.497e-02 | -3.69 | PI3kinase_P85_nSH2 | interpro domains | IPR035022 | 3 | 3 | 18521 | 5414 |
PIK3R2,PIK3R1,PIK3R3 |
| 2.497e-02 | -3.69 | ATPase_F1/V1/A1_a/bsu_N_sf | interpro domains | IPR036121 | 3 | 3 | 18521 | 5414 |
ATP5F1A,ATP6V1A,ATP5F1B |
| 2.497e-02 | -3.69 | USP8_dimer | interpro domains | IPR015063 | 3 | 3 | 18521 | 5414 |
USP8,STAMBP,STAMBPL1 |
| 2.497e-02 | -3.69 | Aconitase/3IPM_dehydase_swvl | interpro domains | IPR015928 | 3 | 3 | 18521 | 5414 |
ACO1,IREB2,ACO2 |
| 2.497e-02 | -3.69 | BRINP | interpro domains | IPR033237 | 3 | 3 | 18521 | 5414 |
BRINP3,BRINP2,BRINP1 |
| 2.497e-02 | -3.69 | Reg_factor_effector_dom_sf | interpro domains | IPR011256 | 3 | 3 | 18521 | 5414 |
HEBP2,HEBP1,TEX264 |
| 2.497e-02 | -3.69 | DFDF | interpro domains | IPR025762 | 3 | 3 | 18521 | 5414 |
EDC3,LSM14A,LSM14B |
| 2.497e-02 | -3.69 | Ribosomal_uL16_sf | interpro domains | IPR036920 | 3 | 3 | 18521 | 5414 |
RPL10,MRPL16,RPL10L |
| 2.497e-02 | -3.69 | FDF_dom | interpro domains | IPR019050 | 3 | 3 | 18521 | 5414 |
EDC3,LSM14A,LSM14B |
| 2.497e-02 | -3.69 | De-COase2_CS | interpro domains | IPR022657 | 3 | 3 | 18521 | 5414 |
ODC1,AZIN1,AZIN2 |
| 2.497e-02 | -3.69 | EID | interpro domains | IPR033258 | 3 | 3 | 18521 | 5414 |
EID2,EID1,EID2B |
| 2.497e-02 | -3.69 | PRK/URK | interpro domains | IPR006083 | 3 | 3 | 18521 | 5414 |
UCK2,UCKL1,UCK1 |
| 2.497e-02 | -3.69 | OS9-like_dom | interpro domains | IPR012913 | 3 | 3 | 18521 | 5414 |
OS9,GNPTG,ERLEC1 |
| 2.497e-02 | -3.69 | ODC_AZ | interpro domains | IPR002993 | 3 | 3 | 18521 | 5414 |
OAZ3,OAZ1,OAZ2 |
| 2.497e-02 | -3.69 | De-COase2_N | interpro domains | IPR022644 | 3 | 3 | 18521 | 5414 |
AZIN2,AZIN1,ODC1 |
| 2.497e-02 | -3.69 | Uridine_kinase-like | interpro domains | IPR000764 | 3 | 3 | 18521 | 5414 |
UCK1,UCK2,UCKL1 |
| 2.497e-02 | -3.69 | RNA_pol_bsu_CS | interpro domains | IPR007121 | 3 | 3 | 18521 | 5414 |
POLR1B,POLR3B,POLR2B |
| 2.497e-02 | -3.69 | Aconitase_4Fe-4S_dom | interpro domains | IPR036008 | 3 | 3 | 18521 | 5414 |
ACO1,IREB2,ACO2 |
| 2.497e-02 | -3.69 | Ala_racemase/Decarboxylase_C | interpro domains | IPR009006 | 3 | 3 | 18521 | 5414 |
ODC1,AZIN2,AZIN1 |
| 2.497e-02 | -3.69 | PH_PKB | interpro domains | IPR039026 | 3 | 3 | 18521 | 5414 |
AKT3,AKT1,AKT2 |
| 2.497e-02 | -3.69 | AconitaseA/IPMdHydase_ssu_swvl | interpro domains | IPR000573 | 3 | 3 | 18521 | 5414 |
IREB2,ACO2,ACO1 |
| 2.497e-02 | -3.69 | De-COase2_C | interpro domains | IPR022643 | 3 | 3 | 18521 | 5414 |
AZIN1,AZIN2,ODC1 |
| 2.497e-02 | -3.69 | TPP/p25 | interpro domains | IPR008907 | 3 | 3 | 18521 | 5414 |
TPPP,TPPP3,TPPP2 |
| 2.497e-02 | -3.69 | Ribosomal_uS11_sf | interpro domains | IPR036967 | 3 | 3 | 18521 | 5414 |
MRPS11,RPS14,MRPL18 |
| 2.497e-02 | -3.69 | PLipase/COase/thioEstase | interpro domains | IPR003140 | 3 | 3 | 18521 | 5414 |
LYPLA2,LYPLA1,LYPLAL1 |
| 2.497e-02 | -3.69 | SOD-like_Cu/Zn_dom_sf | interpro domains | IPR036423 | 3 | 3 | 18521 | 5414 |
CCS,SOD3,SOD1 |
| 2.497e-02 | -3.69 | Glutaredoxin_euk/vir | interpro domains | IPR011899 | 3 | 3 | 18521 | 5414 |
TXNRD3,GLRX2,GLRX |
| 2.497e-02 | -3.69 | SYTL4 (synaptotagmin like 4) | protein interactions | 94121 | 62 | 25 | 19454 | 5460 |
RAB3A,STX1A,CCDC85B,TBC1D1,CEP70,RAB11A,RAB3D,HMG20A,ARF6,ARL10,METAP1,ARL11,HRAS,ARL15,LMNA,STXBP1,TUBA1A,RAB8B,SAR1B,RAB3B,STAU1,TRIM37,FXR2,KRAS,RAB27A |
| 2.497e-02 | -3.69 | CREB3L3 (cAMP responsive element binding protein 3 like 3) | protein interactions | 84699 | 62 | 25 | 19454 | 5460 |
SPPL3,CEP19,RHAG,BAD,CMTR1,TRAF3IP3,SGTA,CEBPG,STX5,FBXW11,CREB3,MAPK4,SLC38A7,DPY30,PRKACB,CSNK2A1,FATE1,KPNA2,CXXC1,AHCYL1,RUSF1,SLC39A9,HCFC2,CREB3L4,CREBZF |
| 2.497e-02 | -3.69 | ZNF397 (zinc finger protein 397) | protein interactions | 84307 | 62 | 25 | 19454 | 5460 |
WDR11,YWHAG,ZNF24,COP1,YWHAZ,CRTAP,ZMYM2,FGFBP1,ZNF174,FAM91A1,SH3BGRL,SNX1,ZNF397,LMO4,NOTCH2,ZNF263,H1-5,RPLP0,SCAND1,P3H1,EZH2,P4HA2,ZKSCAN1,RPL28,RPL4 |
| 2.497e-02 | -3.69 | PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2) | protein interactions | 51422 | 62 | 25 | 19454 | 5460 |
MYH1,GPT,PRKAB1,WDR83,PRKAG1,NLRP9,PDIA6,PGK1,MYH2,MAP1B,NF2,SLC31A1,TPM3,MCM3,GMPS,CDO1,FKBP4,SMPD2,MRPS16,TRAF7,GANAB,MAP1LC3A,DCLRE1C,HNRNPL,DAPK1 |
| 2.497e-02 | -3.69 | TPCN2 (two pore segment channel 2) | protein interactions | 219931 | 62 | 25 | 19454 | 5460 |
WDR11,HNRNPL,OCRL,NDFIP1,STX6,TLCD4,APEX1,ACP2,WDR44,PCDH9,VAMP3,SNX17,VAMP2,FGFR1,RAB6B,CSNK1G3,CERK,TP53,TSR3,RRAGB,USP8,BMPR1A,EHD4,LRP10,ADRA1A |
| 2.497e-02 | -3.69 | LAPTM5 (lysosomal protein transmembrane 5) | protein interactions | 7805 | 62 | 25 | 19454 | 5460 |
SEC61A1,RPRM,CD63,CYB5R3,TECR,AIG1,DCUN1D1,HMOX2,BAG3,USP13,TNFAIP3,HNRNPC,WWP2,ATP1A1,MRPL18,SELENOO,HUWE1,VAMP1,STXBP1,TOM1L2,INSIG2,TP53,UBA52,KRT7,WWP1 |
| 2.497e-02 | -3.69 | CAPG (capping actin protein, gelsolin like) | protein interactions | 822 | 62 | 25 | 19454 | 5460 |
RAB11A,CRIP1,CFL1,SMAD4,ADK,CMBL,MIF,SNX3,SIAH1,CDC5L,APEX1,PPIA,ETFB,TP53,FCF1,SOX2,RAB4A,STX17,PIR,PRDX6,HSPA8,TRUB1,OAZ3,UFM1,RIGI |
| 2.497e-02 | -3.69 | MRC2 (mannose receptor C-type 2) | protein interactions | 9902 | 62 | 25 | 19454 | 5460 |
MTDH,HSPD1,KRAS,EEF1G,ST8SIA4,CER1,ATG16L1,RAF1,TANK,RAB4A,RAC2,PTPN1,VIRMA,ESR2,NDP,LGALS3,SCGB1D1,PPM1D,BRMS1,AKT1,ATG9A,RAB11A,RB1CC1,RHOB,LGALS8 |
| 2.497e-02 | -3.69 | Rcc1 (regulator of chromosome condensation 1) | protein interactions | 100088 | 62 | 25 | 19454 | 5460 |
NUP153,FBXL19,GPAM,SUMO1,NEU1,RANBP1,CHMP2B,TMEM209,NUP107,H3C1,IMP4,KPNA2,NUP50,RNF113A,RPS2,XPO1,RAB11A,NTMT1,R3HCC1,NUP35,SUMO2,GATAD1,UBE2I,FAM177A1,RAN |
| 2.497e-02 | -3.69 | IL1R2 (interleukin 1 receptor type 2) | protein interactions | 7850 | 62 | 25 | 19454 | 5460 |
IL1B,IL1RAP,IL1A,SAR1B,ITM2B,EXOC3,PCLAF,NDUFA12,NUDT16,RTF2,PRR30,DSTYK,CFTR,OCRL,RGS10,LRRC1,GNPAT,EXOC2,EXOC8,USP15,MICB,EXOC5,RHOBTB3,EXOC1,SLC30A5 |
| 2.497e-02 | -3.69 | NUS1 (NUS1 dehydrodolichyl diphosphate synthase subunit) | protein interactions | 116150 | 62 | 25 | 19454 | 5460 |
TSPAN15,BSCL2,HSPA8,AKAP1,HSCB,SLC31A1,LRP3,TMED7,CCDC47,CDC42,OTULINL,CTLA4,RPA2,LMBR1L,KCNA2,SPINT2,RAC2,CX3CL1,MARCHF4,ACTB,RHOJ,APLNR,LRRTM1,RHOB,RIT1 |
| 2.498e-02 | -3.69 | NKAPD1 (NKAP domain containing 1) | protein interactions | 55216 | 161 | 57 | 19454 | 5460 |
MACROH2A1,AP2M1,CSNK2B,EIF4A3,IFI6,SNRNP40,CEP70,ANAPC15,STAC3,HNRNPC,CUL3,MYC,PPIG,UBE2H,CASC3,AP2A1,FYTTD1,MECP2,CCDC106,NKAPD1,COIL,RBM22,TRA2B,ZC3H14,WDR83,SF3A1,MACROH2A2,SDCBP,SRSF1,SRSF10,NKAP,BUD31,TRA2A,GAS8,CSNK2A1,ZCCHC10,ANKRD50,MAGOH,NOS1AP,DDX23,SRSF8,SREK1IP1,ZC3H11A,S100B,RPL31,SRSF4,AP1M1,THRAP3,CDC40,THAP1,ESS2,H2AJ,RAF1,TMEM14B,AAMP,IK,RP9 |
| 2.500e-02 | -3.69 | MIR92A1 (microRNA 92a-1) | protein interactions | 407048 | 77 | 30 | 19454 | 5460 |
STRBP,HNRNPH3,RARS1,P3H1,SF3B1,HNRNPH2,RTCB,HNRNPA2B1,RIGI,G3BP2,HNRNPA0,TRA2B,HNRNPF,HNRNPK,HNRNPA1,CPSF2,NONO,TRA2A,KARS1,GRSF1,WWP2,DDX1,IGF2BP1,CRTAP,SF3B4,SYNCRIP,CPSF1,EIF2AK2,HNRNPL,MATR3 |
| 2.500e-02 | -3.69 | EXT2 (exostosin glycosyltransferase 2) | protein interactions | 2132 | 77 | 30 | 19454 | 5460 |
EXT1,LMBR1L,GXYLT1,CD1A,NOP9,VIRMA,DNAJB9,ELOC,GGH,RPS29,CFC1,SDF2L1,SNCG,TMEM106B,PFDN1,GSKIP,FABP4,SMN1,USP30,GPIHBP1,CLEC2B,DNAJC25,TMEM106A,CDKN1A,PI15,ANXA7,NCR3,PLD3,STK16,SFTPC |
| 2.500e-02 | -3.69 | SNX18 (sorting nexin 18) | protein interactions | 112574 | 77 | 30 | 19454 | 5460 |
MAP1LC3B,SOX2,ATG16L1,FASLG,VDR,ZBTB42,GRAP2,DISC1,ADAMTS1,SDC2,SNX33,EFNB1,FBXO11,EWSR1,SOS2,HSPB2,SLU7,RPA3,SKP1,GABARAP,STAU1,XPO1,MDFI,RELL1,CDC16,CBL,H2AC4,DNM2,CCNF,DYRK1A |
| 2.500e-02 | -3.69 | E7 (transforming protein) | protein interactions | 1489048 | 77 | 30 | 19454 | 5460 |
SELENOW,IRF1,NTAQ1,LYPLAL1,POP7,SCNM1,TSR2,PSMB1,RB1,ACTB,CLIC4,CA8,IGFBP3,EEF1A1,FAM200A,CDKN1A,CNP,SDCBP,MFAP1,PDLIM4,STX8,ZBTB25,PML,PCNA,TRUB1,RING1,RPL3,SPCS2,EEF1G,MT2A |
| 2.505e-02 | -3.69 | gamma-secretase complex | cellular component | GO:0070765 | 7 | 5 | 19108 | 5553 |
PSEN1,PSENEN,APH1A,NCSTN,PSEN2 |
| 2.505e-02 | -3.69 | U7 snRNP | cellular component | GO:0005683 | 7 | 5 | 19108 | 5553 |
SNRPD3,SNRPB,LSM10,SNRPG,SNRPE |
| 2.505e-02 | -3.69 | pre-snoRNP complex | cellular component | GO:0070761 | 7 | 5 | 19108 | 5553 |
NOP58,ZNHIT3,TAF9,ZNHIT6,PIH1D1 |
| 2.507e-02 | -3.69 | T cell apoptotic process | biological process | GO:0070231 | 29 | 14 | 18204 | 5365 |
TP53,AKT1,BCL10,FAS,LMBR1L,DFFA,IL2RA,FASLG,PDCD1,BAK1,KDELR1,LIPA,GPAM,BAX |
| 2.507e-02 | -3.69 | salivary gland morphogenesis | biological process | GO:0007435 | 29 | 14 | 18204 | 5365 |
FGF7,FGFR1,TWSG1,POLB,PAX6,TNF,DAG1,TGFB2,TGFB3,NRP1,FGF10,NKX3-1,CDC42,SEMA3C |
| 2.509e-02 | -3.69 | RXRB (retinoid X receptor beta) | protein interactions | 6257 | 65 | 26 | 19454 | 5460 |
NR1H2,SIAH1,POLR3F,TAF11,CDC5L,NR1I2,MYG1,TRIM27,TADA3,SPOP,NR4A2,MCAT,MAP4,CUL3,TRIM37,FLYWCH2,SPOPL,PLSCR1,PICK1,PPARG,WRAP53,TFCP2,TFIP11,VDR,EXOSC8,PPARA |
| 2.509e-02 | -3.69 | MELTF (melanotransferrin) | protein interactions | 4241 | 65 | 26 | 19454 | 5460 |
PAEP,HSPA5,GPIHBP1,RBCK1,EMC1,DERL1,NUPR1,FGFR1,CFTR,CBLN4,DUSP14,DERL2,PRNP,SFXN2,ELSPBP1,SMG8,ATP1A3,TAFAZZIN,SDF2L1,IQSEC1,GGH,NXPH3,ICOS,HPGDS,CSK,PDIA3 |
| 2.509e-02 | -3.69 | MILR1 (mast cell immunoglobulin like receptor 1) | protein interactions | 284021 | 65 | 26 | 19454 | 5460 |
BTF3L4,EPS8,CMSS1,HSPA14,PDCD10,UBE2S,CHMP2A,TTC9C,EIF3J,UBLCP1,METTL15,RTF2,CHMP1A,DNAJC2,QRSL1,CHAMP1,PLAA,EMG1,ANAPC16,PPP1R12A,INPPL1,PRIM2,CMAS,WDR55,ROCK2,VRK1 |
| 2.509e-02 | -3.69 | THRSP (thyroid hormone responsive) | protein interactions | 7069 | 65 | 26 | 19454 | 5460 |
FZR1,VTI1B,PTPN1,MID1IP1,CNOT6,TSG101,UBE2D1,SMAD4,LCN8,RB1CC1,STK11,CNOT2,AKT1,CDC16,BRMS1,NAPG,KRAS,MBD3,PPP1R12A,INPPL1,IGF1R,PIK3CA,PALS2,ADNP,ACACA,MTA3 |
| 2.509e-02 | -3.69 | CLSTN3 (calsyntenin 3) | protein interactions | 9746 | 65 | 26 | 19454 | 5460 |
PGAP2,TRAM1L1,CLEC2B,TMEM106A,CBLN4,CA14,SFTPC,CMTM7,CLEC12B,GPIHBP1,ST8SIA4,RSPH1,CFC1,TMEM107,SDF2L1,CMA1,KLK5,ST3GAL4,TNFSF13,LMBR1L,ST8SIA5,GXYLT1,NRSN1,CD1A,TMEM97,APEX1 |
| 2.509e-02 | -3.69 | THAP3 (THAP domain containing 3) | protein interactions | 90326 | 74 | 29 | 19454 | 5460 |
CASC3,MRPS26,ELAVL2,RPS5,MRPL9,RIOX2,NOP16,RPS10,BRD9,KRR1,RPL8,RPS3,RPL26L1,GTF2H4,ACTL6A,UBL5,SPTBN1,CXXC1,RPL17,MRPS7,SRSF12,RPS27A,NOP53,TRIM63,H1-6,RPS15,NKRF,HCFC2,LTBR |
| 2.509e-02 | -3.69 | PPTC7 (protein phosphatase targeting COQ7) | protein interactions | 160760 | 74 | 29 | 19454 | 5460 |
AGPAT5,OSTM1,HSDL1,PRDX6,PGK1,CLPB,HMGB1,ASF1A,BCL6,BNIP3L,ZDHHC17,MRPS18C,MRPL22,FAM174A,LAMP2,CALR,PPTC7,CKB,NME2,YWHAB,SLC7A11,S100A6,AIFM1,SSR2,LDLR,GGT7,RBBP4,UBB,DBT |
| 2.509e-02 | -3.69 | POP7 (POP7 homolog, ribonuclease P/MRP subunit) | protein interactions | 10248 | 74 | 29 | 19454 | 5460 |
SMN1,MEPCE,RPP14,POLA2,KRAS,POP5,RPP21,FGL2,RAF1,MOB3C,SART3,POP7,TNFRSF1B,PHB1,ESR2,RPP25,RPP25L,FZR1,RPS16,DDRGK1,ATG7,CUL2,C9orf72,AKT1,RIT1,HSPB1,OSGEP,ATG3,FAS |
| 2.509e-02 | -3.69 | ASPSCR1 (ASPSCR1 tether for SLC2A4, UBX domain containing) | protein interactions | 79058 | 74 | 29 | 19454 | 5460 |
GAPDH,UFD1,PPIB,XAF1,UBXN6,DCAF11,VCPIP1,PSMD14,UBXN10,GLTP,PHAX,CCNF,HNRNPL,KCTD3,VCPKMT,UBXN2B,YTHDF2,DNAJC24,FAM136A,EZH2,BANF1,GLUL,FAF1,RPA3,RIGI,SEPHS1,FTL,YTHDF1,NSFL1C |
| 2.509e-02 | -3.69 | GIMAP5 (GTPase, IMAP family member 5) | protein interactions | 55340 | 74 | 29 | 19454 | 5460 |
TMEM31,AQP3,STOM,ZER1,JAGN1,TMX2,GRAMD2B,EDA2R,CYBRD1,PTGES,CYB561,FCER1G,TM4SF18,PDZK1IP1,BAX,STX1A,BCL2L1,TM4SF19,MGST2,FAM174A,SCN3B,BAK1,FATE1,MGST3,RNASEK,BAD,ELOVL4,RETREG3,TSPAN18 |
| 2.509e-02 | -3.69 | PCSK9 (proprotein convertase subtilisin/kexin type 9) | protein interactions | 255738 | 74 | 29 | 19454 | 5460 |
SLC25A1,MSTN,NXPH3,FAM20C,GGH,TAFAZZIN,SDF2L1,DNAJC10,HSPB1,CDIPT,STUB1,ELSPBP1,DNASE1L1,LDLR,PCSK9,AGK,ARMC6,SLC25A12,FIBIN,PI15,PGRMC1,TRAF2,CBLN4,NCR3,SLC25A10,TMEM87A,BACE1,BIRC2,RPL28 |
| 2.510e-02 | -3.69 | misfolded protein binding | molecular function | GO:0051787 | 16 | 9 | 18094 | 5411 |
EDEM1,STUB1,CLU,DNAJB9,DNAJC3,HSPA5,HDAC6,DNAJC10,SDF2L1 |
| 2.510e-02 | -3.69 | sodium:chloride symporter activity | molecular function | GO:0015378 | 16 | 9 | 18094 | 5411 |
SLC6A11,SLC6A3,SLC12A2,SLC6A8,SLC6A4,SLC6A12,SLC6A6,SLC6A1,SLC6A2 |
| 2.510e-02 | -3.68 | Retinoblastoma (RB) in Cancer | WikiPathways | WP2446 | 88 | 41 | 5310 | 1910 |
RFC4,CCND3,RPA2,RB1,TP53,CCNA2,FANCG,PCNA,CDK1,MCM4,CDK6,CDK4,CDC7,RPA3,TFDP2,MDM2,HMGB1,MYC,CCND1,RFC3,ZNF655,H2AZ1,TYMS,MCM3,SAP30,CCNB1,MCM6,FAF1,RABIF,RAF1,CDKN1A,RBBP7,SUV39H1,PRMT2,CDKN1B,SIN3A,RFC5,MSH6,RBBP4,DCK,RRM1 |
| 2.514e-02 | -3.68 | HEPHL1 (hephaestin like 1) | protein interactions | 341208 | 71 | 28 | 19454 | 5460 |
OR51E2,SEMG2,OAZ3,FOS,FSTL1,FBXO3,TFG,RAB11B,SRSF10,FBXL4,ALCAM,UFL1,VTI1B,CPLX3,ISCA2,KDELR2,PTDSS1,DUSP14,AGPAT1,CSGALNACT1,SGIP1,CCR1,LACC1,STX17,PNMA2,CAPZA2,NPSR1,SYP |
| 2.514e-02 | -3.68 | ND1 (NADH dehydrogenase subunit 1) | protein interactions | 4535 | 71 | 28 | 19454 | 5460 |
NDUFB7,RPL6,NDUFV2,TMEM70,BRCA1,KLK5,TST,SLC11A2,EDNRA,NDUFA1,GATD3,RPL13A,RHOJ,APLNR,TIMMDC1,LPAR6,CDC42,P2RY12,NDUFS6,NDUFS3,CRELD1,NDUFA12,NDUFB5,SYVN1,TACR1,HSCB,LPAR1,DNAJC30 |
| 2.514e-02 | -3.68 | SLC5A6 (solute carrier family 5 member 6) | protein interactions | 8884 | 71 | 28 | 19454 | 5460 |
ORMDL1,SLC35G2,SLC31A1,PXMP2,RIGI,RNASEL,LPCAT3,TP53,YIPF3,TMUB2,SELENOT,ELOVL4,CHRM5,G6PC3,MCL1,SPPL3,LGALS3,SLC25A17,CAV1,ESR2,TMEM38B,SLC25A46,MBLAC2,ORMDL3,MZT2B,MUL1,DNAJC19,FITM2 |
| 2.514e-02 | -3.68 | CTDSPL2 (CTD small phosphatase like 2) | protein interactions | 51496 | 68 | 27 | 19454 | 5460 |
RPL6,ELOC,KPNA6,SPOP,TIAM1,KPNA1,BRD3,CTDSPL2,MYBL2,PRNP,APEX1,ERH,VIRMA,RPL10,PTAR1,NUP153,ELFN2,H1-3,FBXL19,CDK1,IPP,ILF2,NUPR1,ATP5F1E,JAK1,KPNA2,HSPA5 |
| 2.514e-02 | -3.68 | LPGAT1 (lysophosphatidylglycerol acyltransferase 1) | protein interactions | 9926 | 68 | 27 | 19454 | 5460 |
RPA3,TSPAN15,VIPR1,HSPA8,LRRN4CL,HSCB,PSMB10,RNF41,RAF1,SEC62,ST7,IZUMO1,AQP3,FURIN,PLD3,LMBR1L,CCNF,PHB1,SLC1A1,STARD3NL,SEC61B,LYPD6,OPRL1,VIRMA,GPBAR1,CUL3,AGR2 |
| 2.514e-02 | -3.68 | TIMM23 (translocase of inner mitochondrial membrane 23) | protein interactions | 100287932 | 68 | 27 | 19454 | 5460 |
SCN3B,CUL3,RAB2A,SLC25A4,TLCD4,SLC25A12,RNASEK,EGLN3,LMBR1L,RAB35,AIFM1,RPA2,TMEM14B,TMEM184B,CCDC47,FAF2,UFL1,PPAN,SFXN1,PML,JAGN1,TMEM88,RPA3,RNF113A,ABCE1,OPA3,SLC2A8 |
| 2.514e-02 | -3.68 | SLC39A3 (solute carrier family 39 member 3) | protein interactions | 29985 | 68 | 27 | 19454 | 5460 |
CTBP1,CA14,TRAPPC2L,TRAPPC13,CBL,ZMPSTE24,H1-1,B3GNT2,SEC22B,MYH1,KLRD1,TNFSF8,RAB1B,CAND1,MANSC1,RAMP3,PTP4A3,SLC39A9,AIFM1,ARF1,CCNF,MYH2,EED,BSCL2,B4GALT1,SPINT2,EP300 |
| 2.515e-02 | -3.68 | mRNA export from nucleus | biological process | GO:0006406 | 65 | 27 | 18204 | 5365 |
THOC2,SMG5,XPO1,NUP107,DDX39A,MAGOH,POLDIP3,THOC6,ENY2,NCBP2,DDX39B,MAGOHB,NXT2,EIF4E,THOC1,EIF4A3,FYTTD1,ALKBH5,ALYREF,GLE1,NXT1,CHTOP,HNRNPA2B1,ZC3H11A,RBM15B,CASC3,THOC3 |
| 2.518e-02 | -3.68 | CDC45 (cell division cycle 45) | protein interactions | 8318 | 117 | 43 | 19454 | 5460 |
DUSP10,EGLN3,RAMP3,PHB1,CCNF,CD79B,TRAPPC3,ALB,THTPA,TOPBP1,TYROBP,CUL3,FAM174A,ORC5,MYC,CSK,MCM4,MCM3,LAMP3,CCL2,STAU1,GPIHBP1,H3C1,KRAS,HSPA5,GINS3,MCM6,EXD2,BCL7B,ORC6,RPA3,S100B,PCNA,RPA2,GINS4,DTD1,FDFT1,CDK4,KLRD1,CDK7,CDKN1A,ACTR1A,MGARP |
| 2.518e-02 | -3.68 | BAIAP2L1 (BAR/IMD domain containing adaptor protein 2 like 1) | protein interactions | 55971 | 117 | 43 | 19454 | 5460 |
BAG3,AKT1,CDKN3,EPS8,RAB11A,NTRK3,NRP1,BICD2,RHOB,PSMD14,YWHAZ,GSK3A,LMBR1L,ACTB,RHOJ,CDC42,NUDT3,ATG16L1,TANK,CCND1,CSNK1G3,FGFR1,PML,STX7,YWHAH,YWHAG,LAMP2,DPP4,YWHAB,RHOG,RAC2,HRAS,RAB35,MDM2,LANCL1,ARF6,SPPL3,RHOH,FASLG,TP53,RND3,KRAS,EPHA4 |
| 2.518e-02 | -3.68 | ABCF3 (ATP binding cassette subfamily F member 3) | protein interactions | 55324 | 117 | 43 | 19454 | 5460 |
RFXANK,SLC35E1,PPP2R1A,THAP1,SAP18,HSPA5,HNRNPF,STAU1,HSPA8,DCTN3,NLRP9,EP300,RPA3,LGI1,PML,CDKN1B,SPP1,LAMTOR1,NOA1,FBXO7,RIOK2,HDAC6,HSPB8,DDRGK1,CTNNB1,MYC,GSTM3,MOV10,UBXN6,MDFI,RAB11A,CDC5L,FCHSD2,TRIM35,TRIM27,ARL4D,RPS20,ELSPBP1,CCNF,S100A6,MID1IP1,EEF1AKMT3,CIB2 |
| 2.518e-02 | -3.68 | AARSD1 (alanyl-tRNA synthetase domain containing 1) | protein interactions | 80755 | 117 | 43 | 19454 | 5460 |
SMAD4,TRAPPC4,HSPB1,RPL23,CALR,PFDN5,GTF2E1,DERL2,EGLN3,PPP2CB,XPO5,TRIM45,SH3GLB1,TUBA1A,PFDN1,RAD21,PPP1R12A,THG1L,NIF3L1,CALU,SERPINH1,DNAJB6,MLF1,MYC,CREB3,MED22,ALKBH2,FBXO7,RHOJ,TAB1,DYRK1A,CCNF,EIF4A3,RPRD1B,SH3GLB2,HECTD1,LAP3,CFTR,YKT6,SRM,RPA3,ARPC2,TTC1 |
| 2.518e-02 | -3.68 | SHTN1 (shootin 1) | protein interactions | 57698 | 117 | 43 | 19454 | 5460 |
UBE2H,YWHAZ,CAV3,SFN,TXN,ACTB,CCNF,DOK4,TRMT6,CNDP2,KCTD12,HSP90B1,ZCCHC17,PRMT2,PSMC4,LNX2,HSPA5,RNF41,GTF2I,KDM1A,BAP1,MED4,TSNAX,YWHAB,ANKRD49,YWHAH,YWHAG,OR4E2,ZBTB2,ARL6IP5,HNRNPL,TEX30,SP2,MRPL49,TFCP2,RRM1,RNF20,CAPZA1,AHCYL1,PSMA5,PCNA,RAB1A,PSME1 |
| 2.523e-02 | -3.68 | SYNPO (synaptopodin) | protein interactions | 11346 | 177 | 62 | 19454 | 5460 |
JUP,CSNK1G3,TMOD1,NUFIP2,SPTBN1,CD59,PPP1CB,SIPA1L1,SGF29,PACSIN3,PML,SPECC1L,TNFAIP1,ARPC2,HSPA8,MYO6,YWHAZ,MAPRE1,AP2A1,ABCG2,VAMP5,MYC,BAG3,PPP1CC,NONO,CFL2,ARHGAP21,CFL1,ACTB,TMOD3,DAPK3,GNAI2,VIRMA,GNB1,CTTN,AP2M1,RRAS2,CHMP4C,ACTR2,CAPZA2,ARPC3,GNAI3,RAF1,B3GNT2,ACTN4,CAMK2G,FLOT1,PALM2AKAP2,PPP1R12A,CYBRD1,MYO1B,HAPSTR1,NCK1,DNAJC7,MOV10,YWHAG,SPTAN1,PRNP,PPP1R18,HNRNPL,CDC5L,CORO1C |
| 2.525e-02 | -3.68 | negative regulation of secretion | biological process | GO:0051048 | 172 | 63 | 18204 | 5365 |
JAGN1,RAB33B,GNAO1,NPVF,NEO1,SFRP1,RAP1A,ASIC1,RSAD2,CCN3,ERP29,CRHBP,NDUFAF2,IL12B,KCNB1,ADIPOQ,TNF,ENY2,ACVR1C,UCP2,DRD3,LEP,CD200,ADTRP,STXBP6,OPRM1,FCGR2B,PTPN11,VPS4B,LILRB1,IL1B,VAMP8,ADORA1,IL12A,PPP3CA,P2RY1,GABBR1,KCNJ11,DPH3,NPY5R,RAP1B,CRY1,CHGA,UCN,FKBP1B,FGF23,NPSR1,MIR146A,HADH,CNR1,CARTPT,INHA,VAMP3,SYT4,CCR2,OPRK1,GNAI2,OSM,GHRL,GNAZ,GJA1,TNFRSF1B,TSPO |
| 2.529e-02 | -3.68 | Popeye | pfam domains | PF04831 | 3 | 3 | 17795 | 5224 |
POPDC2,BVES,POPDC3 |
| 2.529e-02 | -3.68 | TMEM106_N | pfam domains | PF21002 | 3 | 3 | 17795 | 5224 |
TMEM106C,TMEM106B,TMEM106A |
| 2.529e-02 | -3.68 | NTP_transferase | pfam domains | PF00483 | 3 | 3 | 17795 | 5224 |
EIF2B3,GMPPB,GMPPA |
| 2.529e-02 | -3.68 | Ribosomal_L16 | pfam domains | PF00252 | 3 | 3 | 17795 | 5224 |
MRPL16,RPL10,RPL10L |
| 2.529e-02 | -3.68 | PRKCSH | pfam domains | PF07915 | 3 | 3 | 17795 | 5224 |
OS9,GNPTG,ERLEC1 |
| 2.529e-02 | -3.68 | Orn_Arg_deC_N | pfam domains | PF02784 | 3 | 3 | 17795 | 5224 |
AZIN2,AZIN1,ODC1 |
| 2.529e-02 | -3.68 | PI3K_P85_iSH2 | pfam domains | PF16454 | 3 | 3 | 17795 | 5224 |
PIK3R2,PIK3R3,PIK3R1 |
| 2.529e-02 | -3.68 | RNA_pol_Rpb2_3 | pfam domains | PF04565 | 3 | 3 | 17795 | 5224 |
POLR3B,POLR1B,POLR2B |
| 2.529e-02 | -3.68 | RNA_pol_Rpb2_7 | pfam domains | PF04560 | 3 | 3 | 17795 | 5224 |
POLR3B,POLR2B,POLR1B |
| 2.529e-02 | -3.68 | SSDP | pfam domains | PF04503 | 3 | 3 | 17795 | 5224 |
SSBP2,SSBP4,SSBP3 |
| 2.529e-02 | -3.68 | TMEM106 | pfam domains | PF07092 | 3 | 3 | 17795 | 5224 |
TMEM106A,TMEM106C,TMEM106B |
| 2.529e-02 | -3.68 | CARD_2 | pfam domains | PF16739 | 3 | 3 | 17795 | 5224 |
MAVS,RIGI,IFIH1 |
| 2.529e-02 | -3.68 | BRINP | pfam domains | PF19052 | 3 | 3 | 17795 | 5224 |
BRINP1,BRINP2,BRINP3 |
| 2.529e-02 | -3.68 | RNA_pol_Rpb2_6 | pfam domains | PF00562 | 3 | 3 | 17795 | 5224 |
POLR3B,POLR1B,POLR2B |
| 2.529e-02 | -3.68 | Methyltransf_3 | pfam domains | PF01596 | 3 | 3 | 17795 | 5224 |
LRTOMT,COMTD1,COMT |
| 2.529e-02 | -3.68 | Sod_Cu | pfam domains | PF00080 | 3 | 3 | 17795 | 5224 |
CCS,SOD1,SOD3 |
| 2.529e-02 | -3.68 | Abhydrolase_2 | pfam domains | PF02230 | 3 | 3 | 17795 | 5224 |
LYPLA2,LYPLA1,LYPLAL1 |
| 2.529e-02 | -3.68 | Neurensin | pfam domains | PF14927 | 3 | 3 | 17795 | 5224 |
NRSN2,TMEM74,NRSN1 |
| 2.529e-02 | -3.68 | BolA | pfam domains | PF01722 | 3 | 3 | 17795 | 5224 |
BOLA2B,BOLA3,BOLA1 |
| 2.529e-02 | -3.68 | Cortexin | pfam domains | PF11057 | 3 | 3 | 17795 | 5224 |
CTXN2,CTXN3,CTXN1 |
| 2.529e-02 | -3.68 | Caveolin | pfam domains | PF01146 | 3 | 3 | 17795 | 5224 |
CAV1,CAV3,CAV2 |
| 2.529e-02 | -3.68 | Ribosomal_60s | pfam domains | PF00428 | 3 | 3 | 17795 | 5224 |
RPLP2,RPLP1,RPLP0 |
| 2.529e-02 | -3.68 | SLC35F | pfam domains | PF06027 | 3 | 3 | 17795 | 5224 |
SLC35F2,SLC35F6,SLC35F1 |
| 2.529e-02 | -3.68 | FDF | pfam domains | PF09532 | 3 | 3 | 17795 | 5224 |
LSM14B,LSM14A,EDC3 |
| 2.529e-02 | -3.68 | ODC_AZ | pfam domains | PF02100 | 3 | 3 | 17795 | 5224 |
OAZ2,OAZ3,OAZ1 |
| 2.529e-02 | -3.68 | RNA_pol_Rpb2_2 | pfam domains | PF04561 | 3 | 3 | 17795 | 5224 |
POLR2B,POLR1B,POLR3B |
| 2.529e-02 | -3.68 | PKI | pfam domains | PF02827 | 3 | 3 | 17795 | 5224 |
PKIG,PKIA,PKIB |
| 2.529e-02 | -3.68 | Vps26 | pfam domains | PF03643 | 3 | 3 | 17795 | 5224 |
VPS26A,VPS26C,VPS26B |
| 2.529e-02 | -3.68 | Aconitase | pfam domains | PF00330 | 3 | 3 | 17795 | 5224 |
IREB2,ACO1,ACO2 |
| 2.529e-02 | -3.68 | p25-alpha | pfam domains | PF05517 | 3 | 3 | 17795 | 5224 |
TPPP2,TPPP3,TPPP |
| 2.529e-02 | -3.68 | Aconitase_C | pfam domains | PF00694 | 3 | 3 | 17795 | 5224 |
IREB2,ACO1,ACO2 |
| 2.529e-02 | -3.68 | LSM14 | pfam domains | PF12701 | 3 | 3 | 17795 | 5224 |
LSM14B,LSM14A,EDC3 |
| 2.529e-02 | -3.68 | Myelin_PLP | pfam domains | PF01275 | 3 | 3 | 17795 | 5224 |
GPM6A,GPM6B,PLP1 |
| 2.529e-02 | -3.68 | MITF_TFEB_C_3_N | pfam domains | PF15951 | 3 | 3 | 17795 | 5224 |
TFE3,MITF,TFEB |
| 2.529e-02 | -3.68 | RNA_pol_Rpb2_1 | pfam domains | PF04563 | 3 | 3 | 17795 | 5224 |
POLR1B,POLR2B,POLR3B |
| 2.529e-02 | -3.68 | Ribosomal_S18 | pfam domains | PF01084 | 3 | 3 | 17795 | 5224 |
MRPS18B,MRPS18A,MRPS18C |
| 2.529e-02 | -3.68 | Tmemb_185A | pfam domains | PF10269 | 3 | 3 | 17795 | 5224 |
TMEM60,TMEM185A,TMEM185B |
| 2.529e-02 | -3.68 | Orn_DAP_Arg_deC | pfam domains | PF00278 | 3 | 3 | 17795 | 5224 |
ODC1,AZIN1,AZIN2 |
| 2.529e-02 | -3.68 | T4_deiodinase | pfam domains | PF00837 | 3 | 3 | 17795 | 5224 |
DIO3,DIO2,DIO1 |
| 2.529e-02 | -3.68 | Ribosomal_L10 | pfam domains | PF00466 | 3 | 3 | 17795 | 5224 |
MRTO4,MRPL10,RPLP0 |
| 2.529e-02 | -3.68 | USP8_dimer | pfam domains | PF08969 | 3 | 3 | 17795 | 5224 |
STAMBP,USP8,STAMBPL1 |
| 2.529e-02 | -3.68 | AIF-1 | pfam domains | PF21008 | 3 | 3 | 17795 | 5224 |
AIF1,EFHD2,AIF1L |
| 2.529e-02 | -3.68 | GLTP | pfam domains | PF08718 | 3 | 3 | 17795 | 5224 |
GLTP,CPTP,PLEKHA8 |
| 2.529e-02 | -3.68 | Rep_fac_C | pfam domains | PF08542 | 3 | 3 | 17795 | 5224 |
RFC2,RFC5,RFC4 |
| 2.529e-02 | -3.68 | TLV_coat | pfam domains | PF00429 | 3 | 3 | 17795 | 5224 |
ERVV-2,ERVV-1,ERVFRD-1 |
| 2.529e-02 | -3.68 | HIT | pfam domains | PF01230 | 3 | 3 | 17795 | 5224 |
HINT2,HINT1,FHIT |
| 2.529e-02 | -3.68 | PRK | pfam domains | PF00485 | 3 | 3 | 17795 | 5224 |
UCK1,UCK2,UCKL1 |
| 2.534e-02 | -3.68 | Integration of energy metabolism | REACTOME pathways | R-HSA-163685 | 111 | 45 | 10285 | 3229 |
KCNJ11,GNG12,KCNB1,GNG2,AGPAT1,GNG7,ACACA,STK11,CHRM3,GNB1,PRKACB,PRKCA,PPP2R1A,ADIPOR1,GNA11,SNAP25,AHCYL1,ADCY3,STX1A,ADIPOQ,GNG5,SLC25A4,PLCB1,GNG10,ARL2BP,ADCY2,GNG13,ADIPOR2,PLCB2,GNB4,CACNB3,SLC2A1,GNGT2,GNB3,STXBP1,GNAI2,SLC25A5,GNAQ,GNG11,PPP2CB,GNA14,CACNB2,GNG3,RAP1A,VAMP2 |
| 2.536e-02 | -3.67 | central_nervous_system-midbrain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-midbrain-glioma-astrocytoma_Grade_I | 27 | 13 | 16828 | 4835 |
FGFR1,PIK3CA,AKT1,PPP2R1A,FBXW7,IDH2,CTNNB1,MET,KIT,GNA11,GNAQ,IDH1,KRAS |
| 2.536e-02 | -3.67 | Kaposi_sarcoma | COSMIC cancer mutations | Kaposi_sarcoma | 27 | 13 | 16828 | 4835 |
IDH1,KRAS,HRAS,PTEN,PIK3CA,FGFR1,IDH2,AKT1,JAK2,TP53,CTNNB1,KIT,MET |
| 2.536e-02 | -3.67 | soft_tissue-blood_vessel-Kaposi_sarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-Kaposi_sarcoma | 27 | 13 | 16828 | 4835 |
MET,KIT,CTNNB1,TP53,JAK2,AKT1,IDH2,FGFR1,PIK3CA,PTEN,HRAS,KRAS,IDH1 |
| 2.536e-02 | -3.67 | retina | COSMIC cancer mutations | retina | 27 | 13 | 16828 | 4835 |
PIK3CA,PTEN,KIT,RB1,JAK2,AKT1,FBXW7,RUNX1,EWSR1,SF3B1,STOML2,HRAS,KRAS |
| 2.536e-02 | -3.67 | acinar_adenocarcinoma | COSMIC cancer mutations | acinar_adenocarcinoma | 27 | 13 | 16828 | 4835 |
TP53,CTNNB1,MET,FBXW7,AKT1,PIK3CA,SDC4,FGFR1,PTEN,KRAS,MAP2K1,STK11,SMAD4 |
| 2.537e-02 | -3.67 | peptidyl-prolyl cis-trans isomerase activity | molecular function | GO:0003755 | 42 | 19 | 18094 | 5411 |
PPID,FKBP8,PPIL3,PPWD1,PPIF,FKBP1B,FKBP10,FKBP2,AIPL1,FKBP1A,PPIA,AIP,FKBP14,PPIG,PPIL4,PPIB,PPIH,PPIC,FKBP4 |
| 2.537e-02 | -3.67 | nucleobase-containing compound kinase activity | molecular function | GO:0019205 | 42 | 19 | 18094 | 5411 |
NME2,AK3,NT5C2,UCK1,MPP1,NME4,DLG1,AK2,CASK,AK5,ADK,CLP1,UCK2,DTYMK,GUK1,DCK,NME1,CMPK1,UCKL1 |
| 2.539e-02 | -3.67 | ceramide metabolic process | biological process | GO:0006672 | 97 | 38 | 18204 | 5365 |
ST3GAL2,B3GALT4,B4GALT6,CYP4F22,ITGB8,SPTSSB,B3GALT1,TLCD3B,ST8SIA4,PLA2G15,CERK,B4GALT3,GAL3ST1,ST3GAL5,AGK,ORMDL1,HTRA2,ORMDL3,SGMS2,DEGS1,SMPD2,FA2H,HEXB,ELOVL1,NEU1,UGCG,ST3GAL1,ACER3,SPTSSA,B3GALT2,HEXA,ST6GALNAC3,B4GALT4,CERS2,SGMS1,GALC,CERS6,CLN8 |
| 2.543e-02 | -3.67 | SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3) | protein interactions | 6457 | 139 | 50 | 19454 | 5460 |
STK38,HMGB1,RER1,SNX24,ARHGEF6,DDX39B,PRKCB,RABAC1,MRPS18A,ACACA,SNRPN,RBFOX2,NUDT3,SPINDOC,BUB3,EIF4A2,MAT2B,PAFAH1B3,S100A6,LAMTOR1,RCL1,MAT2A,TUFM,DNAJC5,THRAP3,HSPE1,AKAP12,PRPS1,SCYL2,ADRB1,CHMP4C,RAD23B,RNF8,CMPK1,FASLG,EEF2,DDX39A,TMSB10,SPTAN1,RPL35A,MRPL24,G6PD,FBXO32,RPL32,MTAP,HSPB1,CBL,RBFOX3,CRIP1,SHC3 |
| 2.545e-02 | -3.67 | Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | REACTOME pathways | R-HSA-997272 | 25 | 13 | 10285 | 3229 |
GNG5,GNG10,GNG7,KCNJ3,KCNJ2,GNB1,GABBR1,GNG3,GNGT2,GNB3,KCNJ10,GNG12,GNG2 |
| 2.545e-02 | -3.67 | G protein gated Potassium channels | REACTOME pathways | R-HSA-1296059 | 25 | 13 | 10285 | 3229 |
GNG10,GNG7,KCNJ3,GNG5,GNG3,KCNJ2,GNB1,GABBR1,GNGT2,GNB3,GNG2,KCNJ10,GNG12 |
| 2.545e-02 | -3.67 | ZBP1(DAI) mediated induction of type I IFNs | REACTOME pathways | R-HSA-1606322 | 25 | 13 | 10285 | 3229 |
TLR3,HMGB1,AGER,TICAM1,IKBKB,NFKB1,NFKBIB,MYD88,TBK1,NFKBIA,S100B,DHX9,IRF3 |
| 2.545e-02 | -3.67 | Synthesis and interconversion of nucleotide di- and triphosphates | REACTOME pathways | R-HSA-499943 | 25 | 13 | 10285 | 3229 |
DCTPP1,AK5,NME2,CMPK1,NME1,RRM1,GUK1,AK2,DTYMK,GLRX,TXN,NME4,TXNRD1 |
| 2.545e-02 | -3.67 | Budding and maturation of HIV virion | REACTOME pathways | R-HSA-162588 | 25 | 13 | 10285 | 3229 |
VPS28,CHMP2B,CHMP4C,VPS4B,PPIA,VTA1,VPS4A,TSG101,UBA52,RPS27A,UBB,CHMP5,CHMP2A |
| 2.545e-02 | -3.67 | Activation of G protein gated Potassium channels | REACTOME pathways | R-HSA-1296041 | 25 | 13 | 10285 | 3229 |
GNGT2,GNB3,KCNJ10,GNG12,GNG2,GNG5,GNG10,GNG7,KCNJ3,KCNJ2,GABBR1,GNB1,GNG3 |
| 2.553e-02 | -3.67 | CRELD1 (cysteine rich with EGF like domains 1) | protein interactions | 78987 | 158 | 56 | 19454 | 5460 |
LPCAT3,GPAA1,NDUFB5,GPD2,NDUFS6,NDUFA12,POMT2,MACO1,MTARC2,BCS1L,SPPL3,DERL2,UQCRH,SLC25A17,TLCD4,RMND1,CAMLG,DOLK,NDUFB8,FITM2,EMC4,SLC25A46,SLC38A7,ORMDL3,GABBR1,TLCD1,PTN,LPAR1,EEF1G,RER1,PXMP2,POLA2,CERS6,HSDL1,ORMDL1,NDUFC2,LMBRD2,TRIM68,P2RY12,NUFIP2,PIGW,SLC35F6,SLC16A10,BET1,ST7,LRRC8A,SPCS1,LMBR1L,RMDN3,SLC30A7,GPR89A,NDUFB7,NDUFB6,TMEM38B,CUL3,SLC30A5 |
| 2.553e-02 | -3.67 | ZBTB21 (zinc finger and BTB domain containing 21) | protein interactions | 49854 | 158 | 56 | 19454 | 5460 |
KCTD3,PRNP,SUMO2,NAP1L5,GSTA1,EIF4E2,TNNC2,YWHAB,CAMSAP2,TIAM1,YWHAH,YWHAG,EDC3,SRSF12,ZBTB14,TESK2,FHL3,S100B,STARD13,CBX3,TUBB4B,CRTC2,TP53,KIF1C,MAD2L1,SH3BP4,VIRMA,REEP3,SNRNP40,ZMYM2,CPSF1,CREB1,ZNF330,TBC1D25,CHCHD4,TEX19,YWHAZ,DEPDC1B,MAP3K21,TBC1D1,AR,SFN,CUL3,FAM110B,COIL,KDM1A,HDAC5,FAM53C,RPA3,RTKN,AGAP1,CSNK1A1,RPA2,SIPA1L1,INPP5E,NOTCH2 |
| 2.559e-02 | -3.67 | negative regulation of isotype switching to IgE isotypes | biological process | GO:0048294 | 3 | 3 | 18204 | 5365 |
FOXP3,BCL6,NDFIP1 |
| 2.559e-02 | -3.67 | positive regulation of plasma cell differentiation | biological process | GO:1900100 | 3 | 3 | 18204 | 5365 |
XBP1,IL2,IL10 |
| 2.559e-02 | -3.67 | amino acid import | biological process | GO:0043090 | 3 | 3 | 18204 | 5365 |
SLC38A1,SH3BP4,SLC38A2 |
| 2.559e-02 | -3.67 | ascorbate homeostasis | biological process | GO:0140576 | 3 | 3 | 18204 | 5365 |
CYB561,CYB561D2,CYBRD1 |
| 2.559e-02 | -3.67 | lactone biosynthetic process | biological process | GO:1901336 | 3 | 3 | 18204 | 5365 |
AKR1A1,AKR1B1,RGN |
| 2.559e-02 | -3.67 | response to resveratrol | biological process | GO:1904638 | 3 | 3 | 18204 | 5365 |
KCNJ11,MIR21,KCNJ8 |
| 2.559e-02 | -3.67 | positive regulation of protein localization to endoplasmic reticulum | biological process | GO:1905552 | 3 | 3 | 18204 | 5365 |
AKT1,DDRGK1,RTN4 |
| 2.559e-02 | -3.67 | late endosomal microautophagy | biological process | GO:0061738 | 3 | 3 | 18204 | 5365 |
VPS4A,VPS4B,HSPA8 |
| 2.559e-02 | -3.67 | regulation of mitotic cell cycle DNA replication | biological process | GO:1903463 | 3 | 3 | 18204 | 5365 |
ZMPSTE24,FGFR1,BCL6 |
| 2.559e-02 | -3.67 | negative regulation of calcidiol 1-monooxygenase activity | biological process | GO:0010956 | 3 | 3 | 18204 | 5365 |
NFKB1,GFI1,CYP27B1 |
| 2.559e-02 | -3.67 | norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure | biological process | GO:0002025 | 3 | 3 | 18204 | 5365 |
ADRB3,ADRB2,ADRB1 |
| 2.559e-02 | -3.67 | regulation of glutamine transport | biological process | GO:2000485 | 3 | 3 | 18204 | 5365 |
SLC38A3,LEP,SLC38A1 |
| 2.559e-02 | -3.67 | dendritic cell proliferation | biological process | GO:0044565 | 3 | 3 | 18204 | 5365 |
AZI2,TBK1,BCL2L1 |
| 2.559e-02 | -3.67 | putrescine biosynthetic process from ornithine | biological process | GO:0033387 | 3 | 3 | 18204 | 5365 |
ODC1,AZIN2,AZIN1 |
| 2.559e-02 | -3.67 | regulation of dendritic cell dendrite assembly | biological process | GO:2000547 | 3 | 3 | 18204 | 5365 |
CCL19,CCL21,CCR7 |
| 2.559e-02 | -3.67 | regulation of cardiolipin metabolic process | biological process | GO:1900208 | 3 | 3 | 18204 | 5365 |
TAFAZZIN,PHB2,DNAJC19 |
| 2.559e-02 | -3.67 | positive regulation of vitamin D 24-hydroxylase activity | biological process | GO:0010980 | 3 | 3 | 18204 | 5365 |
VDR,FGF23,CYP27B1 |
| 2.559e-02 | -3.67 | promoter clearance during DNA-templated transcription | biological process | GO:0001109 | 3 | 3 | 18204 | 5365 |
RPRD1A,RPRD1B,SUB1 |
| 2.559e-02 | -3.67 | malate transport | biological process | GO:0015743 | 3 | 3 | 18204 | 5365 |
SLC25A10,UCP2,SLC25A11 |
| 2.559e-02 | -3.67 | substrate localization to autophagosome | biological process | GO:0061753 | 3 | 3 | 18204 | 5365 |
SMURF1,TOM1,STBD1 |
| 2.559e-02 | -3.67 | CTP salvage | biological process | GO:0044211 | 3 | 3 | 18204 | 5365 |
UCK2,UCKL1,UCK1 |
| 2.559e-02 | -3.67 | detection of fungus | biological process | GO:0016046 | 3 | 3 | 18204 | 5365 |
CLEC7A,TLR4,CLEC6A |
| 2.559e-02 | -3.67 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | biological process | GO:1904879 | 3 | 3 | 18204 | 5365 |
MIR1-1,G6PD,CACNB2 |
| 2.559e-02 | -3.67 | regulation of immune complex clearance by monocytes and macrophages | biological process | GO:0090264 | 3 | 3 | 18204 | 5365 |
PLA2G5,CCR2,FCGR2B |
| 2.559e-02 | -3.67 | protein targeting to lysosome involved in chaperone-mediated autophagy | biological process | GO:0061740 | 3 | 3 | 18204 | 5365 |
LAMP2,HSPA8,CLU |
| 2.559e-02 | -3.67 | positive regulation of mitotic centrosome separation | biological process | GO:0046604 | 3 | 3 | 18204 | 5365 |
UBXN2B,RANBP1,NSFL1C |
| 2.559e-02 | -3.67 | L-ascorbic acid biosynthetic process | biological process | GO:0019853 | 3 | 3 | 18204 | 5365 |
RGN,AKR1B1,AKR1A1 |
| 2.559e-02 | -3.67 | detection of bacterial lipopeptide | biological process | GO:0070340 | 3 | 3 | 18204 | 5365 |
TLR6,TLR2,TLR1 |
| 2.559e-02 | -3.67 | RNA polymerase II promoter clearance | biological process | GO:0001111 | 3 | 3 | 18204 | 5365 |
RPRD1B,SUB1,RPRD1A |
| 2.559e-02 | -3.67 | epithelial to mesenchymal transition involved in cardiac fibroblast development | biological process | GO:0060940 | 3 | 3 | 18204 | 5365 |
MIR21,PDCD4,SPRY1 |
| 2.559e-02 | -3.67 | response to triacyl bacterial lipopeptide | biological process | GO:0071725 | 3 | 3 | 18204 | 5365 |
TLR1,TLR2,CD14 |
| 2.559e-02 | -3.67 | isotype switching to IgE isotypes | biological process | GO:0048289 | 3 | 3 | 18204 | 5365 |
BCL6,FOXP3,STAT6 |
| 2.559e-02 | -3.67 | positive regulation of response to oxidative stress | biological process | GO:1902884 | 3 | 3 | 18204 | 5365 |
HDAC6,FADS2,SELENON |
| 2.559e-02 | -3.67 | cerebellar cortex maturation | biological process | GO:0021699 | 3 | 3 | 18204 | 5365 |
ARCN1,CEND1,RERE |
| 2.559e-02 | -3.67 | detection of oxygen | biological process | GO:0003032 | 3 | 3 | 18204 | 5365 |
TGFB3,CYB5R4,SOD2 |
| 2.559e-02 | -3.67 | malate transmembrane transport | biological process | GO:0071423 | 3 | 3 | 18204 | 5365 |
SLC25A10,UCP2,SLC25A11 |
| 2.559e-02 | -3.67 | regulation of activated CD8-positive, alpha-beta T cell apoptotic process | biological process | GO:1905402 | 3 | 3 | 18204 | 5365 |
ARG2,CD274,ST3GAL1 |
| 2.559e-02 | -3.67 | negative regulation of polyamine transmembrane transport | biological process | GO:1902268 | 3 | 3 | 18204 | 5365 |
OAZ1,OAZ2,OAZ3 |
| 2.559e-02 | -3.67 | cerebellum maturation | biological process | GO:0021590 | 3 | 3 | 18204 | 5365 |
ARCN1,CEND1,RERE |
| 2.559e-02 | -3.67 | endoplasmic reticulum mannose trimming | biological process | GO:1904380 | 3 | 3 | 18204 | 5365 |
EDEM2,EDEM1,EDEM3 |
| 2.559e-02 | -3.67 | transforming growth factor beta1 production | biological process | GO:0032905 | 3 | 3 | 18204 | 5365 |
CD2AP,FOXP3,COL3A1 |
| 2.559e-02 | -3.67 | regulation of retrograde trans-synaptic signaling by endocanabinoid | biological process | GO:0099178 | 3 | 3 | 18204 | 5365 |
ABHD6,FABP5,PLCB1 |
| 2.559e-02 | -3.67 | regulation of lymphotoxin A production | biological process | GO:0032681 | 3 | 3 | 18204 | 5365 |
CD86,BCL10,IL17F |
| 2.559e-02 | -3.67 | regulation of chronic inflammatory response to antigenic stimulus | biological process | GO:0002874 | 3 | 3 | 18204 | 5365 |
IL10,TNF,LTA |
| 2.559e-02 | -3.67 | secretion by lung epithelial cell involved in lung growth | biological process | GO:0061033 | 3 | 3 | 18204 | 5365 |
TMEM38B,FGF10,FGF7 |
| 2.559e-02 | -3.67 | negative regulation of protein localization to cilium | biological process | GO:1903565 | 3 | 3 | 18204 | 5365 |
LZTFL1,GDI2,INPP5E |
| 2.559e-02 | -3.67 | establishment of blood-nerve barrier | biological process | GO:0008065 | 3 | 3 | 18204 | 5365 |
CLDN1,HAPLN2,GSTM3 |
| 2.559e-02 | -3.67 | positive regulation of lymphotoxin A production | biological process | GO:0032761 | 3 | 3 | 18204 | 5365 |
IL17F,CD86,BCL10 |
| 2.559e-02 | -3.67 | regulation of iron ion import across plasma membrane | biological process | GO:1904438 | 3 | 3 | 18204 | 5365 |
IFNG,ISCU,MIR210 |
| 2.559e-02 | -3.67 | regulation of vitamin D 24-hydroxylase activity | biological process | GO:0010979 | 3 | 3 | 18204 | 5365 |
VDR,FGF23,CYP27B1 |
| 2.559e-02 | -3.67 | positive regulation of growth hormone receptor signaling pathway | biological process | GO:0060399 | 3 | 3 | 18204 | 5365 |
GHRL,JAK2,MBD5 |
| 2.559e-02 | -3.67 | positive regulation of calcidiol 1-monooxygenase activity | biological process | GO:0060559 | 3 | 3 | 18204 | 5365 |
TNF,IL1B,IFNG |
| 2.559e-02 | -3.67 | positive regulation of interleukin-18-mediated signaling pathway | biological process | GO:2000494 | 3 | 3 | 18204 | 5365 |
TICAM2,NLRP6,CASP4 |
| 2.559e-02 | -3.67 | regulation of cytokine activity | biological process | GO:0060300 | 3 | 3 | 18204 | 5365 |
IL10,NOG,GREM2 |
| 2.559e-02 | -3.67 | regulation of oxygen metabolic process | biological process | GO:2000374 | 3 | 3 | 18204 | 5365 |
LIPT2,MT3,RNF34 |
| 2.559e-02 | -3.67 | purine deoxyribonucleoside diphosphate metabolic process | biological process | GO:0009182 | 3 | 3 | 18204 | 5365 |
NUDT18,AK5,GUK1 |
| 2.559e-02 | -3.67 | positive regulation of protein K48-linked ubiquitination | biological process | GO:1902524 | 3 | 3 | 18204 | 5365 |
NMI,BIRC2,GABARAP |
| 2.559e-02 | -3.67 | NAD-cap decapping | biological process | GO:0110155 | 3 | 3 | 18204 | 5365 |
NUDT16,NUDT12,DXO |
| 2.559e-02 | -3.67 | protein import into mitochondrial intermembrane space | biological process | GO:0045041 | 3 | 3 | 18204 | 5365 |
HSPD1,AIFM1,CHCHD4 |
| 2.559e-02 | -3.67 | cell proliferation involved in heart morphogenesis | biological process | GO:0061323 | 3 | 3 | 18204 | 5365 |
HAND2,TGFBR2,SOX9 |
| 2.559e-02 | -3.67 | oxaloacetate(2-) transmembrane transport | biological process | GO:1902356 | 3 | 3 | 18204 | 5365 |
SLC25A10,SLC25A11,UCP2 |
| 2.559e-02 | -3.67 | cellular response to triacyl bacterial lipopeptide | biological process | GO:0071727 | 3 | 3 | 18204 | 5365 |
TLR1,TLR2,CD14 |
| 2.559e-02 | -3.67 | regulation of Schwann cell proliferation involved in axon regeneration | biological process | GO:1905044 | 3 | 3 | 18204 | 5365 |
CERS2,MIR222,MIR221 |
| 2.561e-02 | -3.66 | Morphine Action Pathway | SMPDB pathways | SMP0000406 | 40 | 22 | 1369 | 531 |
SCN1B,PDIA2,ADRA1A,HTR1A,PPIB,DRD1,SDF2L1,OPRM1,ATP1A3,UGT1A1,ATP1A2,SLC6A3,ATP1A1,PDIA6,ATP1B3,ATP1B1,ERP29,HSPA5,SLC6A4,SLC6A2,KCNIP2,KCND2 |
| 2.561e-02 | -3.66 | ITPRID2 (ITPR interacting domain containing 2) | protein interactions | 6744 | 114 | 42 | 19454 | 5460 |
ZCCHC17,CAPZA2,STIM1,NUPR1,CSNK1A1,SOX2,PPP1CB,FGL2,TRIM37,SGF29,CAMK2G,FKBP8,HSPA5,STX11,HSPA8,ABCE1,BRCA1,YWHAZ,DNAJC10,YWHAB,MAPRE1,VMP1,CBL,FAM107A,TNNC2,CUL3,SFN,IFI16,PPP1CC,AR,TESPA1,YWHAH,BTF3,YWHAG,SNX3,DNAJC1,ESR2,VIRMA,TMPO,CTTN,PTEN,TSG101 |
| 2.564e-02 | -3.66 | 1433ZETA | prints domains | PR00305 | 7 | 5 | 5227 | 1528 |
SFN,YWHAG,YWHAZ,YWHAH,YWHAB |
| 2.564e-02 | -3.66 | B14GALTRFASE | prints domains | PR02050 | 7 | 5 | 5227 | 1528 |
B4GALT4,B4GALT6,B4GALT3,B4GALT1,B4GALT7 |
| 2.566e-02 | -3.66 | Adipocytokine signaling pathway | KEGG pathways | ko04920 | 69 | 32 | 7161 | 2463 |
RXRG,TNFRSF1B,PRKAB1,TNF,PRKAG1,ADIPOR2,AKT2,ACSL4,SLC2A1,CPT1B,CD36,NFKB1,PCK2,AKT3,G6PC3,NFKBIA,NFKBIB,ADIPOR1,ADIPOQ,PRKCQ,PTPN11,TRAF2,PPARA,MAPK10,STK11,IKBKB,LEPR,LEP,SOCS3,NPY,JAK2,AKT1 |
| 2.566e-02 | -3.66 | Adipocytokine signaling pathway | KEGG pathways | hsa04920 | 69 | 32 | 7161 | 2463 |
AKT2,SLC2A1,ACSL4,PCK2,CPT1B,CD36,NFKB1,AKT3,G6PC3,TNFRSF1B,RXRG,TNF,PRKAB1,ADIPOR2,PRKAG1,LEP,LEPR,SOCS3,AKT1,JAK2,NPY,NFKBIA,NFKBIB,ADIPOR1,ADIPOQ,PRKCQ,STK11,IKBKB,PPARA,TRAF2,PTPN11,MAPK10 |
| 2.566e-02 | -3.66 | receptor-mediated endocytosis | biological process | GO:0006898 | 163 | 60 | 18204 | 5365 |
GTF2H2,ACKR3,SYK,LILRB1,CXCR1,RALB,CALY,LDLR,SGIP1,FCHO2,FCGR2B,DRD3,ADRB2,SNAP25,RNASEK,SNAP91,FCHSD2,CXCL8,LRRTM1,LMBR1L,SCYL2,LRP3,FCER1G,PPT1,TMEM108,RALA,TFRC,SNX1,GRIA1,DNM2,ADRB3,RAB5A,CD14,SFTPD,DPP4,FCMR,LILRB4,CD81,LMBRD1,CACNG3,AP2A1,PICALM,CD9,SNX17,CAV1,CLEC9A,FOLR1,ACHE,CAV2,VLDLR,AP2S1,HGS,RAB31,CD36,MRC1,RAMP3,CAV3,AP2M1,CTTN,FCGR1A |
| 2.566e-02 | -3.66 | RNA nuclease activity | molecular function | GO:0004540 | 128 | 49 | 18094 | 5411 |
RNASE9,DCP2,RNASE1,PPP1R8,SAMHD1,PDE12,CNOT6L,APEX1,DBR1,RNASE6,ISG20L2,REXO2,EXOSC3,RNASEH1,RPP25,ISG20,CNOT7,EXOSC4,DROSHA,DICER1,DIS3L,CNOT8,TSEN34,CNOT6,PIWIL3,RNASE4,NUDT16,POP7,PIWIL1,POP5,NOB1,AGO1,PIWIL2,YBEY,RCL1,AZGP1,RNASET2,EXOSC1,PIWIL4,EXD2,CNOT2,RPP21,RNASEK,TSNAX,RNASEL,RPP14,NUDT12,EXOSC8,FEN1 |
| 2.570e-02 | -3.66 | GS_dom | interpro domains | IPR003605 | 7 | 5 | 18521 | 5414 |
ACVR1,BMPR1A,ACVR1C,BMPR1B,ACVR1B |
| 2.570e-02 | -3.66 | Galactosyl_T | interpro domains | IPR003859 | 7 | 5 | 18521 | 5414 |
B4GALT4,B4GALT1,B4GALT7,B4GALT6,B4GALT3 |
| 2.570e-02 | -3.66 | 14-3-3_dom_sf | interpro domains | IPR036815 | 7 | 5 | 18521 | 5414 |
YWHAG,SFN,YWHAZ,YWHAH,YWHAB |
| 2.570e-02 | -3.66 | Galactosyl_T_C | interpro domains | IPR027791 | 7 | 5 | 18521 | 5414 |
B4GALT3,B4GALT6,B4GALT1,B4GALT7,B4GALT4 |
| 2.570e-02 | -3.66 | Galactosyl_T_N | interpro domains | IPR027995 | 7 | 5 | 18521 | 5414 |
B4GALT1,B4GALT7,B4GALT4,B4GALT3,B4GALT6 |
| 2.570e-02 | -3.66 | ELO_fam | interpro domains | IPR002076 | 7 | 5 | 18521 | 5414 |
ELOVL3,ELOVL4,ELOVL1,ELOVL7,ELOVL6 |
| 2.570e-02 | -3.66 | LHFPL | interpro domains | IPR019372 | 7 | 5 | 18521 | 5414 |
LHFPL1,LHFPL2,LHFPL4,LHFPL6,LHFPL7 |
| 2.570e-02 | -3.66 | 14-3-3_CS | interpro domains | IPR023409 | 7 | 5 | 18521 | 5414 |
YWHAB,YWHAH,YWHAZ,SFN,YWHAG |
| 2.570e-02 | -3.66 | Atg8-like | interpro domains | IPR004241 | 7 | 5 | 18521 | 5414 |
GABARAP,MAP1LC3A,MAP1LC3B,GABARAPL2,GABARAPL1 |
| 2.570e-02 | -3.66 | SGNH_hydro_sf | interpro domains | IPR036514 | 7 | 5 | 18521 | 5414 |
PCED1B,IAH1,PAFAH1B2,PAFAH1B3,SIAE |
| 2.570e-02 | -3.66 | 14-3-3_domain | interpro domains | IPR023410 | 7 | 5 | 18521 | 5414 |
YWHAB,YWHAH,YWHAZ,YWHAG,SFN |
| 2.570e-02 | -3.66 | 14-3-3 | interpro domains | IPR000308 | 7 | 5 | 18521 | 5414 |
YWHAG,SFN,YWHAZ,YWHAH,YWHAB |
| 2.574e-02 | -3.66 | UDP-galactose 4-epimerase, domain 1 | gene3d domains | 3.90.25.10 | 5 | 4 | 14470 | 4137 |
GMDS,NMRAL1,GFUS,GALE |
| 2.574e-02 | -3.66 | Porin | gene3d domains | 2.40.160.10 | 5 | 4 | 14470 | 4137 |
VDAC1,VDAC2,TOMM40L,TOMM40 |
| 2.574e-02 | -3.66 | Trafficking protein particle complex subunit 3 | gene3d domains | 3.30.1380.20 | 5 | 4 | 14470 | 4137 |
TRAPPC6A,TRAPPC3,TRAPPC3L,TRAPPC6B |
| 2.574e-02 | -3.66 | - | gene3d domains | 1.10.287.210 | 5 | 4 | 14470 | 4137 |
ERVFRD-1,ERVV-1,ERV3-1,ERVV-2 |
| 2.574e-02 | -3.66 | Isopropylmalate Dehydrogenase | gene3d domains | 3.40.718.10 | 5 | 4 | 14470 | 4137 |
IDH2,IDH3A,IDH3B,IDH1 |
| 2.575e-02 | -3.66 | negative regulation of cell cycle phase transition | biological process | GO:1901988 | 246 | 87 | 18204 | 5365 |
OVOL1,CRLF3,RPA2,FBXO31,SPC24,NOP53,NUF2,TOPBP1,RINT1,FAM107A,SOX2,RPL26,HINFP,PML,CDC5L,PRPF19,MACROH2A1,CDKN1A,NABP1,CCL2,MAD2L1,PTEN,MIR29C,IK,RB1,DCUN1D3,CDK5RAP3,PRMT2,ZNF655,CRADD,CACNB4,H2AX,MIR16-1,NAE1,ACVR1,BUB3,DLG1,CCND1,PSMG2,CTDSP1,CDK2AP2,TP53,MIR133B,GNB1L,ZNF207,MIR873,MDM2,DTL,CDC20,VPS4A,FZR1,MIR15A,IER3,CDK1,RAD1,CTDSP2,JADE1,BTN2A2,KLF4,MIR10A,PTPN11,NDC80,RAD21,MAD2L2,MIR638,FBXO7,RBBP8,MIR137,MIR29A,EZH2,TPRA1,MIR195,CDKN2D,BABAM1,GPNMB,BRCA1,RGCC,KLHL22,MDC1,CDKN1B,MIR193A,CDC73,RPS27L,NBN,UFL1,MIR503,CHMP4C |
| 2.583e-02 | -3.66 | TRIM55 (tripartite motif containing 55) | protein interactions | 84675 | 343 | 113 | 19454 | 5460 |
SRSF7,APLN,ATP5F1D,ZBTB14,PCGF3,PCGF6,RPS4X,E2F4,TMBIM1,KIAA0408,NCSTN,EZH2,ITGB5,ZNF436,SRSF1,LAPTM4A,EED,MPP1,BUD31,TRIM35,SRSF10,PRPF19,ZNF345,CTNNB1,MAP3K14,DNTTIP1,UBE2D1,HSPB1,DCAF11,HIRA,RNF10,DCTN3,EEF1G,PAFAH1B2,MLH3,UCHL3,UBE2D3,SAP18,EHHADH,TOR1AIP2,ALKBH3,FERRY3,USP39,NUFIP2,PELO,IRF2,ATP5F1B,TCAP,USP5,DES,GRB10,HNRNPC,LMO2,MYC,USP13,RHEB,PRRT1,PELI3,THOC6,SPSB1,DHX9,SEPTIN7,RING1,TRIM63,EIF3E,PHF23,KBTBD4,PPARA,ZNF581,IK,NEFL,GABPB1,TNNI1,MSRB3,MLLT11,VAC14,COX4I1,SYNCRIP,NDUFA1,TRMT10B,DECR2,TXNRD3,KCTD15,CDC5L,MALSU1,ID1,IRF3,GFM1,SQSTM1,MRPL41,USP8,PIAS1,PRR30,SF3A1,MYCT1,LIMS2,SF3B6,UBE2I,TRIM27,TRIM54,PYGM,ZBTB17,UBA3,DEK,UBE2L3,IFI35,CARS1,LYNX1,TRAF3IP2,BRAP,TEX19,UBE2E3,TRIM23 |
| 2.587e-02 | -3.65 | negative regulation of lipid biosynthetic process | biological process | GO:0051055 | 68 | 28 | 18204 | 5365 |
ATP1A1,NFKB1,MIR1-1,ERLIN1,DKK3,MIR9-1,ERLIN2,CYP27B1,MIR185,MIR204,CCDC3,FBXW7,CYP7A1,MIR98,SNAI2,INSIG2,KLHL25,DCAF5,SOD1,PROX1,NR0B1,GFI1,ORMDL3,ORMDL1,BRCA1,MIR132,MIR342,MIR206 |
| 2.587e-02 | -3.65 | regulation of cell-substrate junction organization | biological process | GO:0150116 | 68 | 28 | 18204 | 5365 |
THY1,DAPK3,GREM1,ARF6,POLDIP2,IQSEC1,S100A10,SRC,LDB1,PIK3R1,MAPRE2,CORO1C,FAM107A,LAMTOR2,EFNA5,FERMT2,ROCK1,SFRP1,VEGFA,SMAD3,DUSP3,DUSP22,ROCK2,NRP1,MMP14,SDC4,GPM6B,PTEN |
| 2.587e-02 | -3.65 | regulation of antigen receptor-mediated signaling pathway | biological process | GO:0050854 | 68 | 28 | 18204 | 5365 |
RPS3,LPXN,MIR34A,RAB29,PRKCB,TESPA1,DUSP22,ELF1,SLC39A10,DUSP3,FOXP1,LGALS3,CD81,LILRB4,CD226,STAP1,THY1,NECTIN2,CCR7,FCGR2B,PRNP,LIPA,FCMR,BTN2A2,SH2D1A,BCL10,SLA2,PTPN22 |
| 2.594e-02 | -3.65 | KIF13B (kinesin family member 13B) | protein interactions | 23303 | 136 | 49 | 19454 | 5460 |
FAM110B,RAB11A,CUL3,SFN,TBC1D1,DEPDC1B,MAP3K21,YWHAZ,LAMTOR1,TBC1D25,DLG4,REEP3,DEK,VIRMA,SH3BP4,INPP5E,SIPA1L1,STX17,RPA2,CSNK1A1,AGAP1,RTKN,RPA3,FAM53C,HDAC5,UFL1,BCL6,STX7,EDC3,YWHAG,YWHAH,TIAM1,YWHAB,CAMSAP2,ASB7,EIF4E2,ARF6,KCTD3,CAV1,KIF1C,CRTC2,RAB4A,STARD13,CCR1,DLG1,TESK2,BAG2,RIGI,SRSF12 |
| 2.594e-02 | -3.65 | TNRC6C (trinucleotide repeat containing adaptor 6C) | protein interactions | 57690 | 136 | 49 | 19454 | 5460 |
TOMM20,DVL2,RPA3,RPA2,SCLT1,AGO1,TAB1,VIRMA,PRRC2A,KTI12,CNOT6,DLST,SMAP2,AP2M1,TRIM24,NR2E1,BRCA1,DCAF4,AP2A1,OST4,CEP85,CUL3,CNOT7,CNOT6L,TFG,GARRE1,PABPC1,ZC3H7A,GPBP1L1,TBK1,TOP3B,YTHDF2,TNPO2,HNRNPL,CAND1,MIF,CNTROB,ETV6,EIF4E2,FUBP3,PHB1,KRT8,SEC23A,SSX2IP,CNOT2,CNOT8,XPO1,CPEB1,SPATA2 |
| 2.598e-02 | -3.65 | MRI1 (methylthioribose-1-phosphate isomerase 1) | protein interactions | 84245 | 36 | 16 | 19454 | 5460 |
CDK9,PLEKHF2,HSCB,KCTD3,TRUB1,PICK1,NUBP2,RPA3,FBXO32,SEPHS2,PPP3CA,RPE,CFTR,LRRC40,EHD3,PCCB |
| 2.598e-02 | -3.65 | TMSB10 (thymosin beta 10) | protein interactions | 9168 | 36 | 16 | 19454 | 5460 |
ACTB,SNRNP40,LGALS3,SRPK2,SRC,CAV1,INPPL1,PEBP1,EZH2,LMNA,NR2E1,GSTP1,SCLT1,TMOD1,CSK,BAG3 |
| 2.598e-02 | -3.65 | ZC3H12A (zinc finger CCCH-type containing 12A) | protein interactions | 80149 | 36 | 16 | 19454 | 5460 |
IL6,RIGI,ESR2,TRIM63,KPNA2,FZR1,IL1B,CYFIP2,MAVS,EP300,IRF3,SMAD3,TRAF6,XPO1,TANK,TBK1 |
| 2.598e-02 | -3.65 | PLEKHO2 (pleckstrin homology domain containing O2) | protein interactions | 80301 | 36 | 16 | 19454 | 5460 |
FAAP100,MTDH,CAPZA1,RIGI,RNF20,CDC20,RAB11A,VEZT,RAF1,TOP3B,RNF40,CAPZA2,YWHAZ,RHOB,ZMYM6,YWHAB |
| 2.598e-02 | -3.65 | BBC3 (BCL2 binding component 3) | protein interactions | 27113 | 36 | 16 | 19454 | 5460 |
BCL2L1,HGS,BAX,TP53,CREBBP,NDUFAB1,CHCHD2,BCL2A1,BAD,EP300,ALB,UBASH3B,SQSTM1,LDLR,MAP1LC3A,MCL1 |
| 2.598e-02 | -3.65 | ARHGAP44 (Rho GTPase activating protein 44) | protein interactions | 9912 | 36 | 16 | 19454 | 5460 |
ACAT1,TCOF1,ARHGEF6,TMEM263,BCL7B,SURF6,HNRNPL,CASP4,CD2AP,JPT1,CDC42,VPS26A,TOP3B,STK24,NME2,LMNA |
| 2.598e-02 | -3.65 | CXCL6 (C-X-C motif chemokine ligand 6) | protein interactions | 6372 | 36 | 16 | 19454 | 5460 |
CXCL12,EMC4,CXCL1,CCL11,CCL5,TMOD2,CXCR1,CSNK1G3,GNAZ,ARGLU1,CXCL3,GNB3,PPP1R12A,MMP9,CCL8,CXCL10 |
| 2.598e-02 | -3.65 | FBXO4 (F-box protein 4) | protein interactions | 26272 | 36 | 16 | 19454 | 5460 |
MCL1,RCHY1,AP1M1,RNF20,SKP1,NEDD8,UBE2D3,HNRNPK,FBXO7,RNF40,CSK,CCND1,TP53,CDK4,TNNI3K,HSP90AA1 |
| 2.598e-02 | -3.65 | C2orf49 (chromosome 2 open reading frame 49) | protein interactions | 79074 | 36 | 16 | 19454 | 5460 |
TMOD1,DDX1,HNRNPD,YWHAZ,YWHAG,E2F4,MYC,AUH,RAF1,MDC1,SNRNP40,RNASE1,TRIM54,RTCB,RTRAF,DDX39B |
| 2.598e-02 | -3.65 | MNS1 (meiosis specific nuclear structural 1) | protein interactions | 55329 | 36 | 16 | 19454 | 5460 |
CDR2,TNNI1,DISC1,DDX39A,FCHSD2,CCND3,SURF6,TRIM54,KDM1A,PICK1,EWSR1,MNS1,MTDH,MSN,UBE2N,RAB28 |
| 2.598e-02 | -3.65 | ZNF787 (zinc finger protein 787) | protein interactions | 126208 | 36 | 16 | 19454 | 5460 |
PTEN,FGFBP1,ESR2,TOLLIP,PRNP,UFL1,DDRGK1,SOX2,SMARCE1,CUL3,NOTCH2,MYC,STBD1,MOV10,SNRNP70,CDK5RAP3 |
| 2.598e-02 | -3.65 | HIPK4 (homeodomain interacting protein kinase 4) | protein interactions | 147746 | 36 | 16 | 19454 | 5460 |
EEF2,LBR,YTHDF2,RAF1,UBL4A,ATP1A1,HSP90AA1,SFXN2,APPBP2,WDR6,SLC25A10,CCT7,HSP90AB1,TECR,RBBP4,CTSB |
| 2.598e-02 | -3.65 | ARL6 (ADP ribosylation factor like GTPase 6) | protein interactions | 84100 | 36 | 16 | 19454 | 5460 |
RPL29,ARL6IP6,TOR1AIP2,MYL6,GSTP1,YWHAZ,CCT2,SEC61B,PGK1,CCT8,CDC42EP3,ARL6,PTGES3,PPIA,RPL4,ARL6IP5 |
| 2.598e-02 | -3.65 | SC5D (sterol-C5-desaturase) | protein interactions | 6309 | 36 | 16 | 19454 | 5460 |
P2RY1,ATP1B1,YIPF3,SEC62,DDX39A,TSPAN10,TPRA1,TSPAN5,LPAR1,LZTFL1,KRAS,VIPR1,TSPAN17,BSCL2,TSPAN15,LMBR1L |
| 2.598e-02 | -3.65 | KCNC4 (potassium voltage-gated channel subfamily C member 4) | protein interactions | 3749 | 36 | 16 | 19454 | 5460 |
HSPA8,DNAJB4,KCNC1,HERC3,BACE1,KCNA2,STUB1,VIRMA,PRKCE,SLC25A51,GXYLT2,KCNA3,NUS1,UBAC2,ESYT1,SMPD2 |
| 2.598e-02 | -3.65 | ZNF362 (zinc finger protein 362) | protein interactions | 149076 | 36 | 16 | 19454 | 5460 |
NOTCH2,MYC,AR,SOX2,LMNB1,CBX3,BRD3,ZNF330,CPSF1,ZMYM2,PRNP,ASF1A,SNRNP40,HNRNPL,APEX1,COIL |
| 2.598e-02 | -3.65 | WNT10A (Wnt family member 10A) | protein interactions | 80326 | 36 | 16 | 19454 | 5460 |
GID4,ZMYND19,DNAJC3,MAEA,GID8,NOTCH2,EWSR1,MKLN1,RMND5B,LDLR,FBXO22,YPEL5,RANBP10,HSPA5,ARMC8,PRPS1 |
| 2.598e-02 | -3.65 | RDH14 (retinol dehydrogenase 14) | protein interactions | 57665 | 36 | 16 | 19454 | 5460 |
HGS,TSPAN3,RPA2,CNPY3,ASB8,NUP35,CDC20,TSPAN5,TAB1,BRINP2,TACR1,PRKCB,DUSP6,METAP2,LMBR1L,RPA3 |
| 2.598e-02 | -3.65 | PAGE1 (PAGE family member 1) | protein interactions | 8712 | 36 | 16 | 19454 | 5460 |
NAA35,PLPP4,ZMYM6,TFRC,LANCL2,PIP4K2C,CMTM7,GNB1L,CIBAR1,TMEM14B,TMEM254,SLC1A1,MGST3,TMEM60,TNF,ABHD10 |
| 2.600e-02 | -3.65 | response to hexose | biological process | GO:0009746 | 154 | 57 | 18204 | 5365 |
RAB11B,RMI1,KCNJ11,GCLC,PPP3CA,HNF1B,PPARA,AGER,SMAD4,SELENOT,SELENOS,PFKFB2,ZBED3,ICAM1,SMAD3,RAF1,UCP2,SARM1,ACVR1C,TNF,ADIPOQ,PIK3CA,KCNB1,EIF2B3,CLTRN,MIR15A,GPX1,GPAM,TWNK,IGF1R,GLUL,SMAD2,SESN2,XBP1,PCK2,CDKN1B,MIR320A,EIF2B5,NPTX1,MIR146A,OPRK1,CYP7A1,SLC29A1,MIR221,CCDC186,EGR1,TXNIP,VAMP2,SIN3A,PAX6,EIF2B2,FKBP1B,TRA2B,MIRLET7G,CMA1,PRKCB,MIR16-1 |
| 2.601e-02 | -3.65 | sperm plasma membrane | cellular component | GO:0097524 | 14 | 8 | 19108 | 5553 |
TMEM95,HSP90B1,HSPD1,ADAM21,CCR6,ABHD2,HSP90AA1,LYZL6 |
| 2.601e-02 | -3.65 | extrinsic component of synaptic membrane | cellular component | GO:0099243 | 14 | 8 | 19108 | 5553 |
TIAM1,STXBP1,AP2M1,PICALM,RNF10,CRKL,SNAP91,SNAP25 |
| 2.601e-02 | -3.65 | Sin3-type complex | cellular component | GO:0070822 | 14 | 8 | 19108 | 5553 |
RBBP4,CSNK2A1,PHF12,SIN3A,BRMS1L,BRMS1,ING2,MORF4L1 |
| 2.603e-02 | -3.65 | mitochondrial nucleoid | cellular component | GO:0042645 | 46 | 20 | 19108 | 5553 |
HADHA,CLPX,MPG,FASTKD5,TUFM,TWNK,POLDIP2,SLC25A5,UQCC2,SSBP1,SOD2,VDAC1,GRSF1,MTERF2,TERT,ATP5F1B,TFB1M,HSD17B10,VDAC2,DBT |
| 2.603e-02 | -3.65 | nucleoid | cellular component | GO:0009295 | 46 | 20 | 19108 | 5553 |
UQCC2,SLC25A5,SSBP1,SOD2,VDAC1,MTERF2,TERT,GRSF1,ATP5F1B,DBT,VDAC2,HSD17B10,TFB1M,HADHA,CLPX,MPG,TUFM,FASTKD5,TWNK,POLDIP2 |
| 2.603e-02 | -3.65 | GIPC1 (GIPC PDZ domain containing family member 1) | protein interactions | 10755 | 111 | 41 | 19454 | 5460 |
SH3BP4,ESR2,ITGA6,SDC4,MGME1,MOB4,RGS1,FZD3,SLC2A1,MYO6,RHOB,BRCA1,GIPC3,NRP1,MYC,KLHL9,GFUS,LPAR1,TRIM37,TOLLIP,SEMA4C,TOM1,RGS19,RNF41,RIGI,MARS1,BAP1,ATP2B4,EWSR1,LPAR2,ADRB1,HSPA8,DDIT3,IGF1R,RAB5A,NTRK2,DRD3,NUPR1,TPBG,YTHDF2,TOM1L2 |
| 2.603e-02 | -3.65 | PAK5 (p21 (RAC1) activated kinase 5) | protein interactions | 57144 | 111 | 41 | 19454 | 5460 |
GNAI2,ATP5PD,IDE,SPTAN1,RHOJ,INA,PTPMT1,FAM83B,CCDC90B,BAD,ARMC7,HTRA2,YWHAB,EXOSC1,YWHAZ,GCC1,CRBN,YWHAH,NTAQ1,YWHAG,PRPF31,GMPPA,PMPCA,ENKD1,POLDIP2,OXCT1,CHCHD2,FHL3,CLPB,PML,ATPAF2,RPA3,GNAI3,AP2S1,LMNA,ATP5PO,PAK5,SUPT4H1,CDC42,TP53,SUPT5H |
| 2.604e-02 | -3.65 | wound healing | biological process | GO:0042060 | 321 | 111 | 18204 | 5365 |
CHMP1A,ADIPOR2,HSPB1,GNAQ,PPIA,VPS4A,SERPINA1,IL6,P2RY12,ENPP4,GP9,TREML1,F7,SDC4,PIK3CA,CD40LG,FKBP10,TLR4,PIK3CG,PPARA,TFPI,SRC,ELK3,DAG1,CHMP1B,EXT1,ITGAV,P2RY1,CAV3,UBASH3B,AK3,TIMP1,CD36,VEGFA,CHMP2B,BLOC1S3,FZD6,VAV2,F9,SLC6A4,CHMP2A,VWF,F10,HBEGF,CD9,PAPSS2,CLDN1,SERPINC1,MSX2,CHMP4C,JAML,PROS1,CHMP5,C1GALT1C1,FGFR1OP2,GPX1,LACRT,CSRP1,PDIA3,NPR2,FGF10,METAP1,SMAD3,RAF1,TGFB2,IL1A,CX3CL1,SLC7A11,PDCD10,ACTB,NOTCH2,IGF1,ITGA2,PLG,NOG,VPS4B,PDIA2,MPIG6B,CD40,NDNF,PTK7,SERPIND1,WNT7A,PPP3CA,COL3A1,ITGB5,RAP2B,SYK,LCP1,CD34,RAB27A,ILK,MYL12A,CDKN1A,B4GALT1,FGF1,STXBP1,CD151,NLRP6,HPS6,RAB3A,GGCX,PLSCR1,F2,HBB,PRCP,DDR1,ODAM,LMAN1,THBD,CD59 |
| 2.605e-02 | -3.65 | human chr11q13.1 | chromosome location | human chr11q13.1 | 115 | 35 | 26134 | 5823 |
SLC22A12,FAU,SPINDOC,MIR192,SYVN1,FKBP2,RASGRP2,MIR194-2,MRPL49,RNASEH2C,MIR612,CFL1,TRMT112,CATSPERZ,DNAJC4,MAP3K11,PYGM,GPHA2,POLA2,CAPN1,CDC42EP2,FRMD8,BAD,RPS6KA4,OVOL1,EHD1,COX8A,SLC25A45,BANF1,MACROD1,GPR137,CCDC85B,DRAP1,FAM89B,EIF1AD |
| 2.605e-02 | -3.65 | negative regulation of calcium ion transmembrane transport | biological process | GO:1903170 | 51 | 22 | 18204 | 5365 |
FKBP1B,MIR208B,SESTD1,MIR1-1,GPR35,ATP1A2,DRD3,SRI,CRHR1,PPP3R2,MIR200C,TLR9,MIR208A,CLIC2,EPO,FKBP1A,PLN,PPP3CA,GSTM2,TMBIM6,VDAC1,GSTO1 |
| 2.610e-02 | -3.65 | positive regulation of leukocyte mediated immunity | biological process | GO:0002705 | 151 | 56 | 18204 | 5365 |
CD1E,IL12B,XCL1,DDX1,TNF,TFRC,KLRC2,IL6,KMT5B,IL21,TRAF2,CLEC7A,SHLD1,RSAD2,HSPD1,HFE,IL12A,FOXP3,CD40,IL1B,HSPA8,CD1D,SASH3,IL18,NECTIN2,CD1A,STAP1,CD226,NCR3,MICB,STAT6,MAVS,STX7,MAD2L2,RIGI,TICAM1,TYROBP,HMCES,FCGR1A,EXOSC3,LTA,IL23A,B2M,CD28,TRAF6,NLRP3,KIT,CD1C,IL4,SH2D1A,CD1B,TNFSF13,KLRD1,CYRIB,CD81,IL2 |
| 2.611e-02 | -3.65 | postsynapse organization | biological process | GO:0099173 | 109 | 42 | 18204 | 5365 |
PICK1,HDAC6,HOMER1,INA,ARF6,PRNP,DLG4,DLG1,STK38,NPTX1,CRKL,CHRDL1,C1QL2,LHFPL4,WASL,MTMR2,WNT7A,NEFL,NOS1AP,OPHN1,GLRB,C1QL3,HSPA8,NTNG2,STK38L,NLGN2,TMEM108,ACTL9,IGF1R,GPHN,CHRNA7,CTTN,CDC42,ZNF365,CNTNAP1,PTEN,RER1,ACTB,LRRC4,NRP1,NLGN1,ARF1 |
| 2.612e-02 | -3.64 | CDC23 (cell division cycle 23) | protein interactions | 8697 | 232 | 79 | 19454 | 5460 |
NEK2,FHOD3,RPA2,CRYAB,CTBP1,ANAPC16,AKAP1,RPA3,SLC39A9,TOMM20,COIL,NRBF2,SKP1,KDM1A,CRYL1,PHB2,ANAPC15,PRPF31,DEPDC1B,GPRASP3,RBM15B,GORASP2,CDC16,COPS7A,EMILIN1,PYCR2,PYCR1,GPR17,ANAPC4,TRIM27,FOXP3,ANAPC2,OPTN,CCNF,LMBR1L,UBE2S,CDC20,MAD2L1,ESR2,RSL24D1,DYRK1A,BUB3,FBXO22,SIAH1,ANAPC13,SOX2,CRTC2,GTPBP8,TULP3,CSNK1E,PNMA5,SMARCB1,GRAP2,DISC1,MDC1,H3C1,ANAPC11,CTNNBL1,PSMA1,PSMA5,KRAS,XPO1,SUV39H1,UBXN6,LAMTOR2,CDC26,INO80E,SSX2IP,NAB2,CDC23,PEX3,SKIC8,EIF5A2,H2AC4,AIFM1,KLHL7,CDC5L,SMUG1,FZR1 |
| 2.612e-02 | -3.64 | Prolactin Signaling Pathway | WikiPathways | WP2037 | 76 | 36 | 5310 | 1910 |
HRAS,NFKBIA,PPIA,YWHAG,PTPN1,JUN,YWHAZ,CBL,PIK3CG,JAK2,PIK3R2,SRC,RAF1,CTSD,PPIB,PIK3CA,PTPN11,PRL,VAV2,JAK1,NFKBIB,NFKB1,CISH,IRF1,FOS,SOCS3,AKT1,AGAP2,MAP2K1,STAT5A,MYC,ELK1,PIK3R1,STAT1,SHC1,SOCS2 |
| 2.612e-02 | -3.64 | Leptin signaling pathway | WikiPathways | WP2034 | 76 | 36 | 5310 | 1910 |
PIK3R1,ELK1,CCND1,SHC1,STAT1,IKBKB,SOCS2,CDC42,GSK3A,BAX,ROCK1,ROCK2,AKT1,SOCS3,MAP2K1,CREB1,BCL2L1,LEPR,SP1,PTPN11,JAK1,NFKB1,CISH,ACACA,PTPN1,PTEN,EIF4E,HRAS,BAD,IL1B,LEP,PIK3R2,JAK2,CFL2,RAF1,SRC |
| 2.614e-02 | -3.64 | astrocyte projection | cellular component | GO:0097449 | 19 | 10 | 19108 | 5553 |
EIF2S1,SLC7A11,ADGRG1,SYT4,AQP4,SLC1A2,MT3,KCNJ10,GJB2,GRM2 |
| 2.614e-02 | -3.64 | proton-transporting two-sector ATPase complex, catalytic domain | cellular component | GO:0033178 | 19 | 10 | 19108 | 5553 |
ATP6V1C1,ATP6V1G1,ATP5F1B,ATP5F1A,ATP6V1D,ATP5F1D,ATP6V1A,ATP5F1E,ATP6V1E2,ATP6V1G2 |
| 2.616e-02 | -3.64 | ion channel regulator activity | molecular function | GO:0099106 | 140 | 53 | 18094 | 5411 |
SRI,FGF13,RANGRF,AMIGO1,DPP10,ARPP19,FXYD6,TMEM168,DLG1,KCNMB1,PDE4B,KCNMB2,NPY,SCN3B,KCNIP3,VTI1B,SUMO1,FKBP1B,CAV1,PRKCB,VAMP8,SCLT1,SCN1B,AKT1,CHRNA7,GRM2,KCNAB1,FKBP1A,LYNX1,YWHAH,STX8,CFTR,STIM1,STX7,CAV3,KCNIP2,SCN2B,ATP2B4,FGF12,NPY2R,GLRX,SNTA1,STX1A,CHP1,CACNB3,PCSK9,PACSIN3,ADRB2,KCNS1,LAMP2,NHERF1,STOM,CRISP1 |
| 2.616e-02 | -3.64 | kinase activator activity | molecular function | GO:0019209 | 140 | 53 | 18094 | 5411 |
HTR2A,AFAP1L2,CKS1B,TAB1,CCL5,CAB39,TGFBR2,CDK5R1,NBN,STK3,PDE8A,MOB3C,ALKAL1,CKS2,STRADB,TOPBP1,STK4,BCL10,CD40LG,PIK3R1,GHRL,MOB3B,CCND1,GREM1,STAP1,RPLP1,IL6ST,CCND3,PIK3CA,MT3,STK11,IL2,PRKRA,ADIPOQ,LAMTOR3,HBEGF,MAP3K12,EFNA5,AGAP2,RGCC,MNAT1,VEGFA,MAP2K1,CCNB1,RHEB,DELE1,NEK9,PAK2,DUSP19,EPO,CDKN1A,TOM1L1,CCNY |
| 2.617e-02 | -3.64 | EMP24_GP25L | smart domains | SM01190 | 10 | 6 | 9717 | 2575 |
TMED1,TMED5,TMED9,TMED4,TMED7,TMED3 |
| 2.618e-02 | -3.64 | Glyco_transf_7N | pfam domains | PF13733 | 7 | 5 | 17795 | 5224 |
B4GALT7,B4GALT3,B4GALT6,B4GALT1,B4GALT4 |
| 2.618e-02 | -3.64 | ELO | pfam domains | PF01151 | 7 | 5 | 17795 | 5224 |
ELOVL1,ELOVL4,ELOVL6,ELOVL7,ELOVL3 |
| 2.618e-02 | -3.64 | L_HMGIC_fpl | pfam domains | PF10242 | 7 | 5 | 17795 | 5224 |
LHFPL2,LHFPL7,LHFPL6,LHFPL4,LHFPL1 |
| 2.618e-02 | -3.64 | Glyco_transf_7C | pfam domains | PF02709 | 7 | 5 | 17795 | 5224 |
B4GALT4,B4GALT1,B4GALT6,B4GALT3,B4GALT7 |
| 2.618e-02 | -3.64 | ATG8 | pfam domains | PF02991 | 7 | 5 | 17795 | 5224 |
MAP1LC3A,MAP1LC3B,GABARAPL1,GABARAPL2,GABARAP |
| 2.618e-02 | -3.64 | TGF_beta_GS | pfam domains | PF08515 | 7 | 5 | 17795 | 5224 |
ACVR1,BMPR1A,ACVR1B,ACVR1C,BMPR1B |
| 2.618e-02 | -3.64 | 14-3-3 | pfam domains | PF00244 | 7 | 5 | 17795 | 5224 |
SFN,YWHAH,YWHAB,YWHAZ,YWHAG |
| 2.622e-02 | -3.64 | skin-arm-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-arm-other-seborrhoeic_keratosis | 5 | 4 | 16828 | 4835 |
HRAS,PIK3CA,TERT,AKT1 |
| 2.622e-02 | -3.64 | frontobasal | COSMIC cancer mutations | frontobasal | 5 | 4 | 16828 | 4835 |
IDH1,IDH2,CTNNB1,TP53 |
| 2.622e-02 | -3.64 | central_nervous_system-pineal_gland-primitive_neuroectodermal_tumour-medulloblastoma-pineoblastoma | COSMIC cancer mutations | central_nervous_system-pineal_gland-primitive_neuroectodermal_tumour-medulloblastoma-pineoblastoma | 5 | 4 | 16828 | 4835 |
TERT,EWSR1,SMARCB1,DICER1 |
| 2.622e-02 | -3.64 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia_therapy_related | 5 | 4 | 16828 | 4835 |
RUNX1,CBL,HRAS,KRAS |
| 2.622e-02 | -3.64 | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_III | 5 | 4 | 16828 | 4835 |
IDH1,MSH6,IDH2,EZH2 |
| 2.622e-02 | -3.64 | pineoblastoma | COSMIC cancer mutations | pineoblastoma | 5 | 4 | 16828 | 4835 |
DICER1,SMARCB1,EWSR1,TERT |
| 2.622e-02 | -3.64 | breast-carcinoma-medullary_carcinoma | COSMIC cancer mutations | breast-carcinoma-medullary_carcinoma | 5 | 4 | 16828 | 4835 |
AKT1,PIK3CA,TP53,HRAS |
| 2.622e-02 | -3.64 | central_nervous_system-frontotemporal-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-frontotemporal-primitive_neuroectodermal_tumour-medulloblastoma | 5 | 4 | 16828 | 4835 |
IDH2,IDH1,TP53,CTNNB1 |
| 2.622e-02 | -3.64 | skin-forearm-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-forearm-other-seborrhoeic_keratosis | 5 | 4 | 16828 | 4835 |
AKT1,PTPN11,PIK3CA,HRAS |
| 2.622e-02 | -3.64 | complex-atypical | COSMIC cancer mutations | complex-atypical | 5 | 4 | 16828 | 4835 |
KRAS,CTNNB1,PIK3CA,PTEN |
| 2.622e-02 | -3.64 | acute_lymphoblastic_leukaemia_therapy_related | COSMIC cancer mutations | acute_lymphoblastic_leukaemia_therapy_related | 5 | 4 | 16828 | 4835 |
RUNX1,CBL,KRAS,HRAS |
| 2.622e-02 | -3.64 | astroblastoma_Grade_III | COSMIC cancer mutations | astroblastoma_Grade_III | 5 | 4 | 16828 | 4835 |
IDH1,PTEN,IDH2,TP53 |
| 2.622e-02 | -3.64 | endometrium-hyperplasia-complex-atypical | COSMIC cancer mutations | endometrium-hyperplasia-complex-atypical | 5 | 4 | 16828 | 4835 |
PTEN,PIK3CA,KRAS,CTNNB1 |
| 2.622e-02 | -3.64 | meninges-meningioma-xanthomatous | COSMIC cancer mutations | meninges-meningioma-xanthomatous | 5 | 4 | 16828 | 4835 |
NF2,PTEN,KRAS,HRAS |
| 2.622e-02 | -3.64 | xanthomatous | COSMIC cancer mutations | xanthomatous | 5 | 4 | 16828 | 4835 |
HRAS,KRAS,PTEN,NF2 |
| 2.622e-02 | -3.64 | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 5 | 4 | 16828 | 4835 |
RB1,HRAS,KRAS,MYD88 |
| 2.622e-02 | -3.64 | soft_tissue-blood_vessel-haemangioma-cavernous | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma-cavernous | 5 | 4 | 16828 | 4835 |
EWSR1,IDH1,IDH2,KIT |
| 2.622e-02 | -3.64 | large_intestine-colon-other-dysplasia | COSMIC cancer mutations | large_intestine-colon-other-dysplasia | 5 | 4 | 16828 | 4835 |
IDH1,IDH2,KRAS,TP53 |
| 2.622e-02 | -3.64 | skin-ankle-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-ankle-benign_melanocytic_nevus-Spitz | 5 | 4 | 16828 | 4835 |
BAP1,GNA11,HRAS,GNAQ |
| 2.622e-02 | -3.64 | angiocentric | COSMIC cancer mutations | angiocentric | 5 | 4 | 16828 | 4835 |
IDH1,IDH2,KRAS,TERT |
| 2.622e-02 | -3.64 | cavernous | COSMIC cancer mutations | cavernous | 5 | 4 | 16828 | 4835 |
IDH1,EWSR1,IDH2,KIT |
| 2.622e-02 | -3.64 | central_nervous_system-frontal_lobe-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-ependymoma_Grade_III-IV | 5 | 4 | 16828 | 4835 |
TP53,NF2,IDH1,IDH2 |
| 2.622e-02 | -3.64 | skin-hip-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-hip-other-seborrhoeic_keratosis | 5 | 4 | 16828 | 4835 |
AKT1,PTPN11,PIK3CA,HRAS |
| 2.625e-02 | -3.64 | Nucleotide-bd_a/b_plait_sf | interpro domains | IPR012677 | 245 | 86 | 18521 | 5414 |
HNRNPC,RALYL,PPIL4,HNRNPA0,POLDIP3,RBMS2,RBM42,NCBP2,RBM5,ALYREF,HNRNPA1,SRSF7,G3BP2,HNRNPDL,RBM27,SRSF12,BOLL,RBM7,HNRNPH3,IGF2BP1,PABPC1,RBM34,CPEB1,RBMX2,RBM3,EIF4B,SRSF8,RBM38,EWSR1,PABPC5,HNRNPF,UPF3B,RBFOX3,SART3,LEMD3,G3BP1,RBFOX2,SRSF2,RDM1,NONO,TRA2B,RBM12,HNRNPA2B1,LARP4B,SF3B6,RBM41,HNRNPAB,CIRBP,TIA1,SRSF4,CSTF2T,SYNCRIP,SF3B4,UHMK1,R3HCC1,RBM18,EIF3G,IFI35,RBM17,RBM23,SNRPB2,NMI,ELAVL2,NUP35,SNRPA,TNRC6C,PSPC1,RRP7A,HNRNPD,RPL23A,GRSF1,MRPL23,HNRNPL,RBM15B,SRSF1,SNRNP70,HNRNPH2,MATR3,MYEF2,ELAVL4,ZCRB1,RBM22,CELF6,TRA2A,EIF4H,SRSF10 |
| 2.639e-02 | -3.63 | positive regulation of calcium ion transport | biological process | GO:0051928 | 118 | 45 | 18204 | 5365 |
CACNB3,CX3CL1,HCRT,XCL1,CACNB2,CXCL9,CASK,STC1,CCL5,CXCL11,LACRT,IL13,BAX,VMP1,MIR1-1,BAK1,STAC3,GSTM2,CXCL12,TRPC1,CCL3,PPP3CA,THY1,APLNR,HOMER1,SPHK2,CXCL10,NPSR1,PPP3R2,LGALS3,CCL2,CAV1,PLP1,SRI,UCN,MCHR1,DRD1,CCR1,G6PD,GSTO1,TSPO,LILRA2,ATP1B1,F2,STIM1 |
| 2.639e-02 | -3.63 | import into nucleus | biological process | GO:0051170 | 118 | 45 | 18204 | 5365 |
ING1,IPO8,PRKAG1,NUP35,KPNA6,TRAF3IP2,SEC13,DRD1,NUP62,PML,STK4,CDAN1,KPNA1,NUP107,TXNIP,HNRNPA1,RANBP6,TP53,CDKN1A,NFKBIA,SPRN,KPNA2,CSE1L,PPP1R10,SQSTM1,RPL23,STK3,HIKESHI,NUP50,RPAIN,PHB2,NUP153,POLA2,AKT1,HSPA8,RAN,PIK3R1,SYK,TNPO2,LMNA,RANGRF,FAM53C,PPP3CA,TNPO3,FAM53B |
| 2.640e-02 | -3.63 | DDX47 (DEAD-box helicase 47) | protein interactions | 51202 | 171 | 60 | 19454 | 5460 |
G3BP1,KRAS,RAD21,SIAE,RAF1,E2F4,EZH2,RPS11,SART3,RNF8,FURIN,NUPR1,EED,RAC2,FZR1,CAND1,NOP58,RHOH,PRNP,CDC5L,IFI16,DPP4,WWP2,XPO1,DDRGK1,POU5F1,RHOU,RPA3,HDAC5,HSPA8,EXOSC4,RAB5A,EP300,TRA2B,HSCB,STAU1,COIL,FTL,AATF,CDC42,AGO1,RND2,RPA2,CCNF,AP2M1,PTEN,RHOJ,RPGRIP1L,FBXO22,SRPK2,RPL10,ESR2,MYC,BTF3,RBM15B,PSMD14,ATG3,RHOB,CDKL2,UBE2H |
| 2.640e-02 | -3.63 | CNOT2 (CCR4-NOT transcription complex subunit 2) | protein interactions | 4848 | 171 | 60 | 19454 | 5460 |
PSPC1,CCNF,CNOT6,RPS20,FANCD2OS,DYRK1A,PRRC2A,ESR2,CEP85,KANSL3,GADD45B,RC3H2,UHMK1,CCHCR1,BMPR1A,RPA3,CNKSR3,HSPA8,SMG5,SQSTM1,FXR2,HSCB,HDAC3,YTHDF1,BCL6,AKIP1,AGO1,RPA2,CIMIP1,WDCP,RPL12,FUBP3,EIF4E2,PSMB4,SPPL3,RPS16,EGLN3,NUP35,KIAA0232,NFKB1,CNOT8,XPO1,CPEB1,CTNNB1,GARRE1,LSM14A,ZC3H7A,KRAS,CNOT7,G3BP1,CNOT6L,CAPZA1,CFAP68,MACO1,TOP3B,YTHDF2,TNRC6C,CAPZA2,TMEM165,GPBP1L1 |
| 2.642e-02 | -3.63 | iron ion binding | molecular function | GO:0005506 | 152 | 57 | 18094 | 5411 |
TPH2,CYP2F1,CYP4V2,TYW5,EGLN3,SC5D,CYP2R1,CYP2D6,FTHL17,CYP27A1,CYP2C8,CYP17A1,ALKBH3,CDO1,CYP1A1,HBA1,DPH3,P3H1,ALKBH2,CYGB,CYP1B1,FTL,CYP2C9,TF,PHYH,ADO,CYP3A5,FAXDC2,CYP3A43,AOX1,CYP4F12,ACO2,CYP39A1,CYP7A1,OGFOD3,CYP27B1,ABCE1,FXN,CYP21A2,ISCA2,CYP2C18,CYP4F22,CH25H,ISCU,FTH1,CYP11B1,CYP11B2,CALR,FA2H,EGLN2,DNAJC24,CYP26A1,ACP5,P4HA2,CYP4F8,DOHH,MSMO1 |
| 2.644e-02 | -3.63 | cellular response to reactive oxygen species | biological process | GO:0034614 | 136 | 51 | 18204 | 5365 |
GPR37,PDCD10,MDM2,ROMO1,PCNA,IL6,TXN,CYGB,TNFAIP3,RPS3,IL18BP,PRDX3,MIR34A,MIR107,SOD2,MMP9,MT3,PCGF2,PRDX2,JUN,PRDX1,TOP2B,GLRX2,HSPA8,CDK1,SOD3,PEX13,SRC,AIFM1,AKT1,MPV17,HDAC6,STAT6,KLF4,GPR37L1,RHOB,OSER1,CRYGD,NFE2L2,FOS,CCS,MAP1LC3A,OGG1,EZH2,NQO1,CYP1B1,MIRLET7B,FXN,BECN1,PPIF,SOD1 |
| 2.644e-02 | -3.63 | regulation of MAP kinase activity | biological process | GO:0043405 | 136 | 51 | 18204 | 5365 |
MAP3K11,PDCD10,TNF,ADIPOQ,PDCD4,ERP29,GH1,TRAF2,HYAL2,GSTP1,DUSP19,RPS3,DUSP1,FGF16,FGFR1,PTPN22,GHR,INPP5K,PTPN1,RGS2,CD40,TPD52L1,IL1B,SPRY1,TLR6,MAP3K12,PIK3CG,HRAS,DUSP10,STK38,TLR4,TSG101,IL34,FGF1,DVL2,CDK5RAP3,HGS,DEFB114,CAV3,EZH2,TRAF6,KIT,CDK12,NTRK3,MIR218-1,DIRAS1,CCL19,PPARG,TRIB1,DIRAS2,PAQR3 |
| 2.645e-02 | -3.63 | SPATA13 (spermatogenesis associated 13) | protein interactions | 221178 | 17 | 9 | 19454 | 5460 |
YWHAB,VIRMA,SPPL3,YWHAZ,YWHAG,CDC42,YWHAH,DIRAS1,TOP3B |
| 2.645e-02 | -3.63 | Prkn (parkin RBR E3 ubiquitin protein ligase) | protein interactions | 56816 | 17 | 9 | 19454 | 5460 |
UBE2L3,TOMM20,UBE2D1,CISD1,UBE2D3,VDAC1,UBE2E3,MFN1,PSMA4 |
| 2.645e-02 | -3.63 | Abr (active BCR-related gene) | protein interactions | 109934 | 17 | 9 | 19454 | 5460 |
CHCHD2,KCTD12,HAX1,CHCHD3,CCAR1,PRRC2A,ATP5IF1,TOMM40,MCM3 |
| 2.645e-02 | -3.63 | CSAD (cysteine sulfinic acid decarboxylase) | protein interactions | 51380 | 17 | 9 | 19454 | 5460 |
TOP3B,MOV10,RAP1B,CDKN1A,SPPL3,FZR1,NR1H2,ANXA7,SMN1 |
| 2.645e-02 | -3.63 | ZNF358 (zinc finger protein 358) | protein interactions | 140467 | 17 | 9 | 19454 | 5460 |
KCTD17,RPS10,RPL17,PTTG1,NOTCH2,RPSA,RPS3,FGF13,RPL23A |
| 2.645e-02 | -3.63 | RCAN3 (RCAN family member 3) | protein interactions | 11123 | 17 | 9 | 19454 | 5460 |
TRIM23,PPP3CA,ARMT1,ZDHHC17,EPS8,GRB10,CDK4,SMYD3,PRDX6 |
| 2.645e-02 | -3.63 | CASP12 (caspase 12 (gene/pseudogene)) | protein interactions | 100506742 | 17 | 9 | 19454 | 5460 |
CASP12,TRIM23,STAT1,UBE2K,CRYAB,HSPA5,RNF8,MYC,TRAF2 |
| 2.645e-02 | -3.63 | ZDHHC22 (zinc finger DHHC-type palmitoyltransferase 22) | protein interactions | 283576 | 17 | 9 | 19454 | 5460 |
CLSTN3,RPRM,TMEM88,DDX39A,ATP5IF1,LDLRAD4,ARL6IP5,FNDC9,TMEM14B |
| 2.645e-02 | -3.63 | TULP4 (TUB like protein 4) | protein interactions | 56995 | 17 | 9 | 19454 | 5460 |
BAG3,FAM168A,DLG1,WWP2,TOP3B,VIRMA,CASK,RNF7,HNRNPL |
| 2.645e-02 | -3.63 | RGS10 (regulator of G protein signaling 10) | protein interactions | 6001 | 17 | 9 | 19454 | 5460 |
GNAZ,GNAI3,DNAJB6,SAP18,ADRB2,PLEKHF2,ACP6,GNAO1,IL1R2 |
| 2.645e-02 | -3.63 | LAMA2 (laminin subunit alpha 2) | protein interactions | 3908 | 17 | 9 | 19454 | 5460 |
CSK,H1-5,RPSA,SNAPIN,H2BC9,DAG1,TRIM63,ZDHHC15,H1-1 |
| 2.645e-02 | -3.63 | PLCE1 (phospholipase C epsilon 1) | protein interactions | 51196 | 17 | 9 | 19454 | 5460 |
SIAH1,KIT,VIRMA,CSNK1A1,MDM2,HSP90AA1,TP53,HRAS,SIAH2 |
| 2.645e-02 | -3.63 | MRAS (muscle RAS oncogene homolog) | protein interactions | 22808 | 17 | 9 | 19454 | 5460 |
RAF1,RHOU,MRAS,PSMC5,ELOC,RAPGEF5,HUWE1,PIK3CA,SHOC2 |
| 2.645e-02 | -3.63 | SCN1B (sodium voltage-gated channel beta subunit 1) | protein interactions | 6324 | 17 | 9 | 19454 | 5460 |
CNTN1,RNF115,UBB,RNF126,KCND3,SCN2B,DHRS7,ADRA1A,TTC1 |
| 2.645e-02 | -3.63 | PKDCC (protein kinase domain containing, cytoplasmic) | protein interactions | 91461 | 17 | 9 | 19454 | 5460 |
STUB1,CCT5,CCT8,PDCD5,CCT7,AK2,CCT2,TCP1,PRNP |
| 2.645e-02 | -3.63 | RIN1 (Ras and Rab interactor 1) | protein interactions | 9610 | 108 | 40 | 19454 | 5460 |
PICK1,FLCN,MTDH,RAB5A,DCTN3,ZBED1,KRAS,TRAF2,RFXANK,TFIP11,KLHL12,CCM2,FGFR1,RRAS2,TRIM27,SNX17,RB1,TRAK2,TES,CRYBB3,HRAS,COMT,EEF1AKMT3,HMG20A,SPINDOC,HSPB8,YWHAH,YWHAG,TBC1D1,RAP2B,MDFI,UBXN6,MYC,SPRED1,GSTM3,SMAD2,YWHAB,IVNS1ABP,TRIM23,YWHAZ |
| 2.645e-02 | -3.63 | SYDE1 (synapse defective Rho GTPase homolog 1) | protein interactions | 85360 | 108 | 40 | 19454 | 5460 |
RAC2,EIF4E2,LURAP1,SH3BP4,CDK9,MAD2L2,KCTD3,PRDX2,POLR2I,PRNP,RHOJ,TYW3,YWHAH,DEPDC1B,XPO1,MAP3K21,YWHAG,EDC3,KLHL22,PYCR2,PYCR1,FAM110B,TBC1D25,YWHAB,CAMSAP2,TIAM1,FAM53C,TESK2,RTKN,SRSF12,AZGP1,HSPE1,KPNA2,RPAP2,SIPA1L1,CDC42,ATG16L1,KIF1C,POLR2D,AGAP1 |
| 2.646e-02 | -3.63 | OBI1 (ORC ubiquitin ligase 1) | protein interactions | 79596 | 133 | 48 | 19454 | 5460 |
DNAJC7,AHSA1,UBE2D1,XPO1,CNOT8,CNOT2,ORC5,MOV10,IFI16,LRWD1,EGLN3,KLHL12,HDAC11,MACO1,TBK1,CNOT6L,TTC4,CNOT7,SEM1,GALNT12,BAG2,HAPSTR1,GARRE1,BCKDK,UBE2H,DNAJB6,UHMK1,RC3H2,FAM83A,LDHB,SFN,CUL3,SRPK2,FANCD2OS,PHF21A,CNOT6,CTNNA1,BAD,RPA2,RPP21,CCND1,KDM1A,UFL1,HSCB,SMG5,BAP1,CD40,RPA3 |
| 2.646e-02 | -3.63 | ZFP91 (ZFP91 zinc finger protein, atypical E3 ubiquitin ligase) | protein interactions | 80829 | 133 | 48 | 19454 | 5460 |
USP5,SRPK2,RPL19,VIRMA,ZNF330,RPS3,ATG3,RPL7A,PYCARD,HNRNPAB,SMARCA5,CEP70,STAU1,FTSJ1,HSPA5,EP300,HSPA8,NOTCH2,RPS10,ZBTB2,SRSF1,MAGED2,H2AC4,ECD,CRBN,BRD3,RPS2,DDX50,MAP3K14,HNRNPA1,HNRNPF,CHCHD2,H3C1,SSRP1,PAEP,RPL31,RPL23A,RPL3,PICK1,RING1,ZNF526,CBX3,DLG3,TP53,E2F4,DHX38,RAF1,AURKAIP1 |
| 2.646e-02 | -3.63 | human chr10q24.32 | chromosome location | human chr10q24.32 | 41 | 15 | 26134 | 5823 |
POLL,CYP17A1,NPM3,FBXW4,BORCS7,SUFU,WBP1L,HPS6,ACTR1A,TRIM8,SFXN2,LDB1,LBX1,ELOVL3,KCNIP2 |
| 2.652e-02 | -3.63 | response to estrogen | biological process | GO:0043627 | 71 | 29 | 18204 | 5365 |
AR,TRIM24,DTYMK,MIR493,OPRK1,SP1,HSP90AA1,CTNNA1,TGFB3,WNT7A,GHRL,MME,BGLAP,MSTN,CITED1,CRHBP,ESR2,SFRP1,SERPINB9,CYP27B1,PELP1,MMP14,WBP2,EP300,GSTM3,CAV1,F7,MDM2,EPO |
| 2.663e-02 | -3.63 | regulation of Schwann cell migration | biological process | GO:1900147 | 7 | 5 | 18204 | 5365 |
CERS2,MIR221,MIR222,RRAS2,TIAM1 |
| 2.663e-02 | -3.63 | limb joint morphogenesis | biological process | GO:0036022 | 7 | 5 | 18204 | 5365 |
COL3A1,OSR2,ERRFI1,CTNNB1,EXT1 |
| 2.663e-02 | -3.63 | inflammatory cell apoptotic process | biological process | GO:0006925 | 7 | 5 | 18204 | 5365 |
PLEKHO2,ZMPSTE24,IL6,IRF3,FASLG |
| 2.663e-02 | -3.63 | cerebellar granule cell differentiation | biological process | GO:0021707 | 7 | 5 | 18204 | 5365 |
MTPN,OPHN1,PROX1,WNT7A,CBLN1 |
| 2.663e-02 | -3.63 | antigen processing and presentation, exogenous lipid antigen via MHC class Ib | biological process | GO:0048007 | 7 | 5 | 18204 | 5365 |
CD1C,CD1B,CD1A,CD1D,CD1E |
| 2.663e-02 | -3.63 | regulation of myosin-light-chain-phosphatase activity | biological process | GO:0035507 | 7 | 5 | 18204 | 5365 |
TNF,ROCK2,PPP1R12A,IKBKB,ROCK1 |
| 2.663e-02 | -3.63 | regulation of lymphangiogenesis | biological process | GO:1901490 | 7 | 5 | 18204 | 5365 |
VASH1,EPHA2,VEGFC,VEGFA,MIR9-1 |
| 2.663e-02 | -3.63 | negative regulation of myofibroblast differentiation | biological process | GO:1904761 | 7 | 5 | 18204 | 5365 |
RB1,MIR9-1,PDCD4,TP53INP1,MIR98 |
| 2.663e-02 | -3.63 | positive regulation of protein deacetylation | biological process | GO:0090312 | 7 | 5 | 18204 | 5365 |
NDN,BRMS1,DYRK1A,HDAC6,IFNG |
| 2.663e-02 | -3.63 | cerebellar granular layer formation | biological process | GO:0021684 | 7 | 5 | 18204 | 5365 |
OPHN1,PROX1,MTPN,CBLN1,WNT7A |
| 2.663e-02 | -3.63 | positive regulation of IRE1-mediated unfolded protein response | biological process | GO:1903896 | 7 | 5 | 18204 | 5365 |
BAK1,AGR2,PTPN1,TMEM33,BAX |
| 2.663e-02 | -3.63 | regulation of isotype switching to IgE isotypes | biological process | GO:0048293 | 7 | 5 | 18204 | 5365 |
BCL6,FOXP3,STAT6,IL4,NDFIP1 |
| 2.663e-02 | -3.63 | cellular response to erythropoietin | biological process | GO:0036018 | 7 | 5 | 18204 | 5365 |
CD40,KIT,EPO,MT2A,MT1X |
| 2.663e-02 | -3.63 | regulation of monocyte extravasation | biological process | GO:2000437 | 7 | 5 | 18204 | 5365 |
MIR146A,CD47,CCR2,PLCB1,AGER |
| 2.663e-02 | -3.63 | fatty acid elongation, unsaturated fatty acid | biological process | GO:0019368 | 7 | 5 | 18204 | 5365 |
ELOVL1,ELOVL7,ELOVL4,ELOVL3,ELOVL6 |
| 2.663e-02 | -3.63 | fatty acid elongation, monounsaturated fatty acid | biological process | GO:0034625 | 7 | 5 | 18204 | 5365 |
ELOVL1,ELOVL7,ELOVL6,ELOVL4,ELOVL3 |
| 2.663e-02 | -3.63 | cerebral cortex regionalization | biological process | GO:0021796 | 7 | 5 | 18204 | 5365 |
ADGRG1,EMX2,EMX1,PAX6,TRA2B |
| 2.663e-02 | -3.63 | interleukin-4-mediated signaling pathway | biological process | GO:0035771 | 7 | 5 | 18204 | 5365 |
JAK1,STAT6,IL2RG,STAT5A,IL4 |
| 2.663e-02 | -3.63 | response to erythropoietin | biological process | GO:0036017 | 7 | 5 | 18204 | 5365 |
MT1X,MT2A,KIT,EPO,CD40 |
| 2.663e-02 | -3.63 | positive regulation of axon extension involved in axon guidance | biological process | GO:0048842 | 7 | 5 | 18204 | 5365 |
CXCL12,BMPR2,SEMA5A,NRP1,VEGFA |
| 2.663e-02 | -3.63 | fatty acid elongation, polyunsaturated fatty acid | biological process | GO:0034626 | 7 | 5 | 18204 | 5365 |
ELOVL3,ELOVL4,ELOVL6,ELOVL7,ELOVL1 |
| 2.663e-02 | -3.63 | peptidyl-serine dephosphorylation | biological process | GO:0070262 | 7 | 5 | 18204 | 5365 |
PPTC7,PPP5C,DUSP1,PPP3CA,PPP2CB |
| 2.663e-02 | -3.63 | antigen processing and presentation of lipid antigen via MHC class Ib | biological process | GO:0048003 | 7 | 5 | 18204 | 5365 |
CD1B,CD1C,CD1E,CD1A,CD1D |
| 2.663e-02 | -3.63 | isoleucine metabolic process | biological process | GO:0006549 | 7 | 5 | 18204 | 5365 |
ACAT1,HSD17B10,ILVBL,ACADSB,SDS |
| 2.663e-02 | -3.63 | negative regulation of membrane depolarization | biological process | GO:1904180 | 7 | 5 | 18204 | 5365 |
CAV3,IFI6,BOK,SRC,ALB |
| 2.663e-02 | -3.63 | astrocyte cell migration | biological process | GO:0043615 | 7 | 5 | 18204 | 5365 |
NR2E1,HEXB,CCL2,CCL3,MMP14 |
| 2.663e-02 | -3.63 | interleukin-3-mediated signaling pathway | biological process | GO:0038156 | 7 | 5 | 18204 | 5365 |
SYK,STAT5A,JAK2,IL3,FCER1G |
| 2.663e-02 | -3.63 | regulation of mitochondrial ATP synthesis coupled electron transport | biological process | GO:1905446 | 7 | 5 | 18204 | 5365 |
MIR210,GHITM,CCNB1,CDK1,CHCHD2 |
| 2.663e-02 | -3.63 | extracellular exosome biogenesis | biological process | GO:0097734 | 7 | 5 | 18204 | 5365 |
COPS5,CD34,TSG101,RAB11A,RAB27A |
| 2.663e-02 | -3.63 | negative regulation of transcription initiation by RNA polymerase II | biological process | GO:0060633 | 7 | 5 | 18204 | 5365 |
HMGB1,MYC,ZNF451,CTNNBIP1,HEY2 |
| 2.669e-02 | -3.62 | TGF-beta Signaling Pathway | WikiPathways | WP366 | 133 | 59 | 5310 | 1910 |
SPTBN1,WWP1,CAV1,FOS,TP53,ROCK1,CDK1,MET,MYC,SMAD2,SHC1,ATF3,CDC42,COL1A2,E2F4,SRC,EP300,PARD6A,COPS5,UBE2I,NUP153,FOXP3,KLF10,EID2,SMAD3,TGFB1I1,AKT1,MAP2K1,MAP2K6,MAP2K3,SMAD4,PIK3R1,TRAF6,MEF2A,TERT,CCND1,SKP1,STAMBPL1,JUNB,PML,SUMO1,TAB1,CREBBP,JUN,PIK3R2,SMURF1,SNIP1,CDKN1A,MEF2C,TGFBR2,MAPK4,RAF1,SP1,CITED1,HGS,ITGA2,PAK2,SIN3A,PIAS1 |
| 2.672e-02 | -3.62 | adenine nucleotide transport | biological process | GO:0051503 | 40 | 18 | 18204 | 5365 |
LRRC8C,LRRC8B,SLC25A23,SLC25A24,SLC25A4,LRRC8A,SLC25A5,SLC25A31,LRRC8D,SHOC2,ANKH,SLC25A51,SLC25A17,ABCC5,CD47,CALHM3,SLC35B3,SLC25A42 |
| 2.672e-02 | -3.62 | cellular response to lipoprotein particle stimulus | biological process | GO:0071402 | 40 | 18 | 18204 | 5365 |
SOCS5,MIR20A,TICAM1,SYK,FCER1G,TXNIP,MYD88,LDLR,AKT1,CD36,TLR6,CDH13,PPARG,CD81,MIR146A,TLR4,ADTRP,CD9 |
| 2.673e-02 | -3.62 | ornithine decarboxylase inhibitor activity | molecular function | GO:0008073 | 3 | 3 | 18094 | 5411 |
OAZ1,OAZ3,OAZ2 |
| 2.673e-02 | -3.62 | thyroxine 5'-deiodinase activity | molecular function | GO:0004800 | 3 | 3 | 18094 | 5411 |
DIO1,DIO3,DIO2 |
| 2.673e-02 | -3.62 | interleukin-15 receptor activity | molecular function | GO:0042010 | 3 | 3 | 18094 | 5411 |
IL15RA,IL2RG,IL2RB |
| 2.673e-02 | -3.62 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | GO:0047237 | 3 | 3 | 18094 | 5411 |
EXTL2,CSGALNACT2,CSGALNACT1 |
| 2.673e-02 | -3.62 | oxidoreductase activity, acting on phosphorus or arsenic in donors | molecular function | GO:0030613 | 3 | 3 | 18094 | 5411 |
GSTO1,GSTO2,GLRX2 |
| 2.673e-02 | -3.62 | purine-nucleoside phosphorylase activity | molecular function | GO:0004731 | 3 | 3 | 18094 | 5411 |
MTAP,PNP,LACC1 |
| 2.673e-02 | -3.62 | protein kinase C inhibitor activity | molecular function | GO:0008426 | 3 | 3 | 18094 | 5411 |
YWHAG,SFN,HSPB1 |
| 2.673e-02 | -3.62 | farnesyltranstransferase activity | molecular function | GO:0004311 | 3 | 3 | 18094 | 5411 |
FDFT1,GGPS1,COX10 |
| 2.673e-02 | -3.62 | oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor | molecular function | GO:0030614 | 3 | 3 | 18094 | 5411 |
GSTO2,GSTO1,GLRX2 |
| 2.673e-02 | -3.62 | peptide YY receptor activity | molecular function | GO:0001601 | 3 | 3 | 18094 | 5411 |
NPY5R,NPY1R,NPY2R |
| 2.673e-02 | -3.62 | NADPH dehydrogenase (quinone) activity | molecular function | GO:0008753 | 3 | 3 | 18094 | 5411 |
CBR3,NQO1,CBR4 |
| 2.673e-02 | -3.62 | beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase | molecular function | GO:0047288 | 3 | 3 | 18094 | 5411 |
ST3GAL4,ST3GAL2,ST3GAL1 |
| 2.673e-02 | -3.62 | iron chaperone activity | molecular function | GO:0034986 | 3 | 3 | 18094 | 5411 |
DPH3,TF,FXN |
| 2.673e-02 | -3.62 | interleukin-2 receptor activity | molecular function | GO:0004911 | 3 | 3 | 18094 | 5411 |
IL2RB,IL2RG,IL2RA |
| 2.673e-02 | -3.62 | endoplasmic reticulum-autophagosome adaptor activity | molecular function | GO:0140506 | 3 | 3 | 18094 | 5411 |
RETREG3,RETREG1,RETREG2 |
| 2.673e-02 | -3.62 | aconitate hydratase activity | molecular function | GO:0003994 | 3 | 3 | 18094 | 5411 |
IREB2,ACO2,ACO1 |
| 2.673e-02 | -3.62 | oxaloacetate transmembrane transporter activity | molecular function | GO:0015131 | 3 | 3 | 18094 | 5411 |
UCP2,SLC25A10,SLC25A11 |
| 2.673e-02 | -3.62 | CCR10 chemokine receptor binding | molecular function | GO:0031735 | 3 | 3 | 18094 | 5411 |
CXCL13,CCL19,CCL25 |
| 2.673e-02 | -3.62 | ribonucleoside binding | molecular function | GO:0032549 | 3 | 3 | 18094 | 5411 |
POLR3B,POLR2B,POLR1B |
| 2.673e-02 | -3.62 | C-4 methylsterol oxidase activity | molecular function | GO:0000254 | 3 | 3 | 18094 | 5411 |
FAXDC2,MSMO1,CH25H |
| 2.673e-02 | -3.62 | prostaglandin-D synthase activity | molecular function | GO:0004667 | 3 | 3 | 18094 | 5411 |
PTGES,HPGDS,PTGDS |
| 2.673e-02 | -3.62 | endoplasmic reticulum-organelle membrane tether activity | molecular function | GO:0170009 | 3 | 3 | 18094 | 5411 |
RETREG2,RETREG1,RETREG3 |
| 2.673e-02 | -3.62 | 17-beta-hydroxysteroid dehydrogenase (NADP+) activity | molecular function | GO:0072582 | 3 | 3 | 18094 | 5411 |
DHRS11,HSD17B3,HSD17B1 |
| 2.673e-02 | -3.62 | malate transmembrane transporter activity | molecular function | GO:0015140 | 3 | 3 | 18094 | 5411 |
SLC25A10,UCP2,SLC25A11 |
| 2.673e-02 | -3.62 | interleukin-2 binding | molecular function | GO:0019976 | 3 | 3 | 18094 | 5411 |
IL2RB,IL2RA,IL2RG |
| 2.673e-02 | -3.62 | adiponectin binding | molecular function | GO:0055100 | 3 | 3 | 18094 | 5411 |
ADIPOR1,ADIPOR2,CDH13 |
| 2.673e-02 | -3.62 | ornithine decarboxylase activity | molecular function | GO:0004586 | 3 | 3 | 18094 | 5411 |
AZIN1,AZIN2,ODC1 |
| 2.673e-02 | -3.62 | 3 iron, 4 sulfur cluster binding | molecular function | GO:0051538 | 3 | 3 | 18094 | 5411 |
ACO1,ACO2,SDHB |
| 2.682e-02 | -3.62 | sex chromosome | cellular component | GO:0000803 | 35 | 16 | 19108 | 5553 |
MAEL,BIRC2,H2AX,BRCA1,RING1,PCGF2,LRIF1,SUMO1,UBE2B,MACROH2A2,H2AZ1,MACROH2A1,SMARCB1,PCGF3,SMCHD1,PHC1 |
| 2.684e-02 | -3.62 | WDR86 (WD repeat domain 86) | protein interactions | 349136 | 25 | 12 | 19454 | 5460 |
TCP1,CCT2,CCT7,PFDN4,PFDN1,PDCL,PDRG1,CCT5,CCT8,HSPD1,IPCEF1,HSPA8 |
| 2.684e-02 | -3.62 | NFE2 (nuclear factor, erythroid 2) | protein interactions | 4778 | 25 | 12 | 19454 | 5460 |
ELF5,NFE2L2,SCAND1,WWP1,MAFG,NFE2L1,CREBBP,ATF4,NFE2,TXN,UBE2I,PHYHIP |
| 2.684e-02 | -3.62 | Naa11 (N(alpha)-acetyltransferase 11, NatA catalytic subunit) | protein interactions | 97243 | 25 | 12 | 19454 | 5460 |
HYPK,RBCK1,FZR1,NPM3,HSD17B10,TTC1,POLR3B,CPNE2,NAA50,NAA16,NAA15,H1-3 |
| 2.684e-02 | -3.62 | CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit) | protein interactions | 1139 | 25 | 12 | 19454 | 5460 |
PPP1CC,CFTR,UBLCP1,PIK3R1,DCAKD,OSBPL8,SNX14,UBAC2,GUCY1B1,PPWD1,UFL1,PRNP |
| 2.684e-02 | -3.62 | ALS2 (alsin Rho guanine nucleotide exchange factor ALS2) | protein interactions | 57679 | 25 | 12 | 19454 | 5460 |
STXBP6,ATG3,YWHAZ,WDR20,PDCD10,YWHAB,ATG7,YWHAG,YWHAH,CHN2,ATG4C,ZYX |
| 2.684e-02 | -3.62 | TRHDE (thyrotropin releasing hormone degrading enzyme) | protein interactions | 29953 | 25 | 12 | 19454 | 5460 |
LCN6,MAN1A2,ICOS,AKT1,VAMP5,CLRN2,TSPAN3,FIBIN,LEMD3,DNAJB9,MUL1,FKBP14 |
| 2.684e-02 | -3.62 | STK19 (serine/threonine kinase 19) | protein interactions | 8859 | 25 | 12 | 19454 | 5460 |
SLC29A1,TIMM13,TIMM8A,PCCB,PFDN5,POLR2G,TRIM23,PICK1,SF3B4,HSPD1,BHLHE40,ASB3 |
| 2.684e-02 | -3.62 | SLC35E3 (solute carrier family 35 member E3) | protein interactions | 55508 | 25 | 12 | 19454 | 5460 |
SPG21,BAG3,CSGALNACT2,SELENOK,TMEM14B,FXYD6,SLC66A2,SSMEM1,RUSF1,PLP1,ADIPOQ,TMEM60 |
| 2.684e-02 | -3.62 | LRRC27 (leucine rich repeat containing 27) | protein interactions | 80313 | 25 | 12 | 19454 | 5460 |
IFT52,SPECC1L,POLA2,RIGI,HNRNPL,WDR19,DDX39A,LRRC40,MAP1S,TP53,MCM8,H2AC4 |
| 2.684e-02 | -3.62 | LCTL (lactase like) | protein interactions | 197021 | 25 | 12 | 19454 | 5460 |
PSMD14,GHITM,BTN2A2,LEMD3,NUS1,DHRS7,SLC25A46,ST3GAL2,NETO2,DIPK1A,SC5D,ZDHHC17 |
| 2.684e-02 | -3.62 | CEP112 (centrosomal protein 112) | protein interactions | 201134 | 25 | 12 | 19454 | 5460 |
VIRMA,S100B,SQSTM1,PNMA2,YWHAZ,YWHAB,SFN,API5,FBXO7,YWHAG,MAP1LC3B,YWHAH |
| 2.684e-02 | -3.62 | CABCOCO1 (ciliary associated calcium binding coiled-coil 1) | protein interactions | 219621 | 25 | 12 | 19454 | 5460 |
RBM12,CFTR,HMOX2,UBLCP1,GNPDA2,MOB3C,CYRIB,SFXN1,RAP1B,SNX1,SNX2,RDH11 |
| 2.684e-02 | -3.62 | KLHL28 (kelch like family member 28) | protein interactions | 54813 | 25 | 12 | 19454 | 5460 |
ALB,KLHL24,VIRMA,NUDCD3,PRKACB,KLHL9,CUL3,KLHL26,KLHL12,VAPB,IPP,CAAP1 |
| 2.684e-02 | -3.62 | ARC (activity regulated cytoskeleton associated protein) | protein interactions | 23237 | 25 | 12 | 19454 | 5460 |
INSYN1,DDX39A,NDE1,TOP3B,SUMO1,PIP4P2,FAM83B,UBE3A,STUB1,KRAS,SUMO3,SUMO2 |
| 2.684e-02 | -3.62 | ZNF558 (zinc finger protein 558) | protein interactions | 148156 | 25 | 12 | 19454 | 5460 |
EIF1AD,ALB,HEXIM2,TF,FTL,MAD2L2,CUL3,MOV10,CSNK2A1,TIAM1,SERPINA1,MFAP1 |
| 2.684e-02 | -3.62 | FBP2 (fructose-bisphosphatase 2) | protein interactions | 8789 | 25 | 12 | 19454 | 5460 |
FBP1,SMAD2,STK11,SMAD4,FBP2,PIK3CA,RB1,CTNNA1,BMPR1A,SRC,FBXW7,MLH3 |
| 2.684e-02 | -3.62 | AIFM2 (apoptosis inducing factor mitochondria associated 2) | protein interactions | 84883 | 25 | 12 | 19454 | 5460 |
CDR2,DHRS4,MYC,TP53,TRIM54,ECHDC1,CNPY4,HSD17B11,SESTD1,NDUFA4,SPECC1L,FBXO32 |
| 2.686e-02 | -3.62 | ORC2 (origin recognition complex subunit 2) | protein interactions | 4999 | 105 | 39 | 19454 | 5460 |
HBB,FOXS1,CBX3,LMNA,RPA2,EZH2,ILF2,PARD6A,TP53,BRINP1,CCNA2,CARTPT,CRYBA4,NUCKS1,CCL2,KRAS,H3C1,MCM6,XRCC5,S100B,ALKBH4,ORC6,RPA3,EP300,STN1,BRCA1,MCM8,MYC,ORC5,HMGA1,AR,MCM3,MCM4,RUNX1,CDC5L,LRWD1,ESR2,CBX5,ZNF330 |
| 2.686e-02 | -3.62 | IRF2BP2 (interferon regulatory factor 2 binding protein 2) | protein interactions | 359948 | 105 | 39 | 19454 | 5460 |
PAX6,HDAC3,ASF1A,TRIM37,KLF10,BAG2,RPA3,PML,IRF2BPL,SSBP3,RPA2,KLF3,SOX2,UPRT,E2F4,GCHFR,VIRMA,NUP35,DEK,HMG20A,EIF4H,IRF2BP1,THOC1,FBXO22,KCTD10,GANAB,NUDT9,TES,IRF2,SIN3A,ELK3,VGLL4,FOSL2,LDB1,GMPS,AR,LMO2,MYC,CUL3 |
| 2.686e-02 | -3.62 | AKTIP (AKT interacting protein) | protein interactions | 64400 | 105 | 39 | 19454 | 5460 |
ENO1,SURF2,VDAC2,HACD3,UQCRC2,RPLP2,PSMC5,ACTB,DYNC1I2,MATR3,PRDX2,CAND1,TXN,HNRNPL,SPPL3,TRIM35,FHIP1B,MARCHF5,AKT1,TRIM32,GAPDH,DDRGK1,LMNB1,TRIM23,SSX2IP,HSPD1,HADHA,TWNK,NDUFS2,NAB1,PDHB,VPS16,EIF3E,VPS28,POLA2,EEF2,VPS18,LMNA,PGGT1B |
| 2.694e-02 | -3.61 | CXC_Chemokine_domain | interpro domains | IPR033899 | 14 | 8 | 18521 | 5414 |
CXCL8,CXCL3,CXCL12,CXCL11,CXCL10,CXCL1,CXCL9,CXCL13 |
| 2.694e-02 | -3.61 | GLA-like_dom_SF | interpro domains | IPR035972 | 14 | 8 | 18521 | 5414 |
BGLAP,F2,F7,F10,PROS1,F9,MGP,PRRG1 |
| 2.694e-02 | -3.61 | GLA_domain | interpro domains | IPR000294 | 14 | 8 | 18521 | 5414 |
F7,BGLAP,F2,PRRG1,MGP,F9,PROS1,F10 |
| 2.694e-02 | -3.61 | Translation_prot_SH3-like_sf | interpro domains | IPR008991 | 14 | 8 | 18521 | 5414 |
RPL26L1,RPL8,RPL27,MRPL24,EIF5A2,RPL6,RPL26,SUPT5H |
| 2.698e-02 | -3.61 | immune response-regulating cell surface receptor signaling pathway | biological process | GO:0002768 | 262 | 92 | 18204 | 5365 |
TICAM2,KIT,TLR2,CD14,TRAF6,CLEC12B,CD38,CD2AP,CTLA4,LAT2,CRKL,TMEM126A,TBK1,UBE2N,KLRD1,PAK2,TLR5,TIRAP,CD200R1,OAS1,FCGR1A,PRKCE,CACNB4,NFKB1,PRKCB,FOSL2,CD40,PTPN22,MBL2,SYK,MAPK10,STK11,HRAS,CREBBP,FCGR2B,NCR3,CACNB3,FCN2,NFKBIA,EP300,YES1,LY96,EIF2B3,PIK3AP1,FCGR2A,KLRC2,IRAK4,SLA2,PRKCQ,MYD88,CD3G,PSEN1,EIF2B5,CD247,LILRB4,LCP2,FCMR,LILRA2,VAV2,NMI,RC3H2,RBCK1,CLEC6A,IKBKB,TYROBP,TICAM1,MOG,ITK,EIF2B2,MEF2C,CD28,LILRB1,BCL10,SRC,FOXP3,PLPP4,CD79B,TLR4,PDE4B,THY1,IRF3,BTN2A2,MICB,SPPL3,FCER1G,FGR,PIK3CA,STOML2,CSK,CLEC7A,SPG21,BAX |
| 2.698e-02 | -3.61 | RSPH1 (radial spoke head component 1) | protein interactions | 89765 | 130 | 47 | 19454 | 5460 |
BTG3,B4GALT3,TUBB,METAP2,TUBA1B,CTTN,FAIM,SRXN1,CRMP1,OAT,ZBTB38,CXXC5,SMARCE1,CLU,CMAS,TRIM52,ZBTB5,NHP2,NF2,MIA2,RNF10,SF3B1,DCTN6,CNPPD1,SH3GLB2,GAMT,CREBZF,CLSTN3,CORO1C,DNAJC7,SNRNP70,RHOG,LGI3,EIF3D,PAX6,FLOT1,NETO1,TF,TOLLIP,GLUL,CASK,MTMR2,POLR2C,PNMA2,TUBB4B,EEF2,WBP11 |
| 2.698e-02 | -3.61 | FECH (ferrochelatase) | protein interactions | 2235 | 130 | 47 | 19454 | 5460 |
PGRMC1,RPA2,MTRES1,HECTD1,ATPAF2,RPA3,MME,AMACR,GFM1,RNF113A,HSCB,FBXW7,AUH,FMC1,CUL3,PMPCA,MRM2,TUFM,ATG3,DNAJB6,UBE2H,CTTN,CCDC90B,MRPL23,TMOD3,ROCK1,ESR2,FBP1,MRPL11,PPP2R1A,DDX39A,PDHA1,HSPD1,HINT2,COX8A,IMMP2L,COPS5,ATG7,TMEM70,POU5F1,SSBP1,PPP2CB,FAHD1,GATD3,HNRNPL,FZR1,MALSU1 |
| 2.699e-02 | -3.61 | PCSK7 (proprotein convertase subtilisin/kexin type 7) | protein interactions | 9159 | 12 | 7 | 19454 | 5460 |
FURIN,HSPA5,HNRNPD,PABPC1,TRIM54,SPPL3,SYNCRIP |
| 2.699e-02 | -3.61 | Actr1a (ARP1 actin-related protein 1A, centractin alpha) | protein interactions | 54130 | 12 | 7 | 19454 | 5460 |
ACTB,DCTN4,DCTN6,PTEN,DCTN3,ACTR1B,ACTR1A |
| 2.699e-02 | -3.61 | TNFRSF18 (TNF receptor superfamily member 18) | protein interactions | 8784 | 12 | 7 | 19454 | 5460 |
SIVA1,NIF3L1,TNFSF18,IDE,TRAF2,HSPA5,TRAF1 |
| 2.699e-02 | -3.61 | HEBP2 (heme binding protein 2) | protein interactions | 23593 | 12 | 7 | 19454 | 5460 |
MOV10,BAP1,HNRNPD,PRNP,PLEKHF2,HNRNPL,EIF1B |
| 2.699e-02 | -3.61 | RPL17-C18orf32 (RPL17-C18orf32 readthrough) | protein interactions | 100526842 | 12 | 7 | 19454 | 5460 |
TMPO,RPL17,RIT1,RAF1,KRAS,STAU1,TRIM37 |
| 2.699e-02 | -3.61 | RNU4ATAC (RNA, U4atac small nuclear) | protein interactions | 100151683 | 12 | 7 | 19454 | 5460 |
PRPF4,PRPF31,USP39,LSM4,DDX23,LSM2,SNRNP40 |
| 2.699e-02 | -3.61 | GSTA4 (glutathione S-transferase alpha 4) | protein interactions | 2941 | 12 | 7 | 19454 | 5460 |
GSTO1,GSTA4,GSTA2,NTAQ1,BAG3,GAS8,GSTA1 |
| 2.699e-02 | -3.61 | OAZ2 (ornithine decarboxylase antizyme 2) | protein interactions | 4947 | 12 | 7 | 19454 | 5460 |
ODC1,AZIN2,CDR2,OAZ1,MOV10,MYC,AZIN1 |
| 2.699e-02 | -3.61 | ANKRD2 (ankyrin repeat domain 2) | protein interactions | 26287 | 12 | 7 | 19454 | 5460 |
PML,TP53,MICB,BRD3,FCMR,HBP1,TCAP |
| 2.699e-02 | -3.61 | METAP1D (methionyl aminopeptidase type 1D, mitochondrial) | protein interactions | 254042 | 12 | 7 | 19454 | 5460 |
METAP1,CSK,PAK5,NDUFC2,RIGI,CPEB1,CRAT |
| 2.699e-02 | -3.61 | LMP-1 (latent membrane protein LMP-1) | protein interactions | 3783750 | 12 | 7 | 19454 | 5460 |
TNFAIP3,TNIK,ZMYND11,TRAF2,SLC2A1,TRAF1,TAB2 |
| 2.699e-02 | -3.61 | Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1) | protein interactions | 15516 | 12 | 7 | 19454 | 5460 |
YWHAZ,CFTR,PTEN,CCNF,STUB1,CCNB1,DNAJB2 |
| 2.699e-02 | -3.61 | PRDM7 (PR/SET domain 7) | protein interactions | 11105 | 12 | 7 | 19454 | 5460 |
TRAF1,RPS27A,ZDHHC15,FHL3,SPIN3,SNRPD2,CFL2 |
| 2.699e-02 | -3.61 | TM7SF2 (transmembrane 7 superfamily member 2) | protein interactions | 7108 | 12 | 7 | 19454 | 5460 |
CHRM4,TSPAN15,EED,NMRAL1,RAP2A,DISC1,PLD3 |
| 2.699e-02 | -3.61 | GDF3 (growth differentiation factor 3) | protein interactions | 9573 | 12 | 7 | 19454 | 5460 |
PQBP1,MICB,NPTX1,VPS39,CALR,IDH3B,SELENOO |
| 2.699e-02 | -3.61 | Hspa8 (heat shock protein 8) | protein interactions | 15481 | 12 | 7 | 19454 | 5460 |
STUB1,C9orf72,CCNF,SOD1,PTEN,YWHAZ,H3C1 |
| 2.699e-02 | -3.61 | FBXO24 (F-box protein 24) | protein interactions | 26261 | 12 | 7 | 19454 | 5460 |
SRPK2,SKP1,DDX39A,HSP90AA1,NME1,PRMT6,RAF1 |
| 2.699e-02 | -3.61 | Rab11fip1 (RAB11 family interacting protein 1 (class I)) | protein interactions | 75767 | 12 | 7 | 19454 | 5460 |
NUP62,ZKSCAN1,CLK1,UTP6,CHMP1B,SNRNP48,RAB11B |
| 2.699e-02 | -3.61 | CCDC121 (coiled-coil domain containing 121) | protein interactions | 79635 | 12 | 7 | 19454 | 5460 |
RINT1,UBE2E3,LTBR,KDM1A,NUP62,TBC1D17,TFIP11 |
| 2.699e-02 | -3.61 | ZNF268 (zinc finger protein 268) | protein interactions | 10795 | 12 | 7 | 19454 | 5460 |
RBPJ,COMMD8,RNF208,TP53,CUL3,MRFAP1L1,SLC31A1 |
| 2.699e-02 | -3.61 | ARMCX1 (armadillo repeat containing X-linked 1) | protein interactions | 51309 | 12 | 7 | 19454 | 5460 |
CEP70,COIL,POU5F1,PICK1,TFIP11,EZH2,MYC |
| 2.699e-02 | -3.61 | UMAD1 (UBAP1-MVB12-associated (UMA) domain containing 1) | protein interactions | 729852 | 12 | 7 | 19454 | 5460 |
TFG,RBCK1,DDX39A,BIRC2,TRAF2,GABARAPL1,TSG101 |
| 2.699e-02 | -3.61 | GCOM1 (GCOM1, MYZAP-POLR2M combined locus) | protein interactions | 145781 | 12 | 7 | 19454 | 5460 |
CBL,POLR2B,POLR2C,POLR2F,RPAP2,RPA3,ATG16L1 |
| 2.701e-02 | -3.61 | Trk receptor signaling mediated by PI3K and PLC-gamma | Pathway Interaction DB | pi3kplctrkpathway | 32 | 17 | 2226 | 782 |
AKT1,YWHAZ,CCND1,YWHAG,YWHAB,SFN,GAB1,YWHAH,BAD,AGAP2,PIK3R1,SHC1,CREB1,SRC,EGR1,PIK3CA,STAT5A |
| 2.710e-02 | -3.61 | calcium ion homeostasis | biological process | GO:0055074 | 231 | 82 | 18204 | 5365 |
RMDN3,SNX10,CALR,BOK,CACNB2,STC1,STOML2,CCL5,VAPB,SELENOK,BAX,VDR,BAK1,ADORA1,HTR2A,CXCL12,CD40,TRPC1,CCL23,TMBIM6,P2RY1,FGFR1,P2RY4,CCL3,ATF4,TMEM165,SMDT1,DRD3,CCL11,GRM1,PSEN2,SLC25A23,CCL8,FGF23,PML,HSP90B1,CYP27B1,EDNRA,CAV2,ALPL,MAIP1,ATP2B4,NPPC,CAV1,DISC1,KCTD17,ANKH,CIB2,HEXB,CAV3,CHRNA7,FKBP1B,TPT1,CCR1,PRKCB,CACNB4,CCL1,ZNHIT1,NPTN,DMPK,TMEM203,CCDC47,PLN,RGN,GRIA1,ATP2C1,TRIM24,SLC8A1,FATE1,CNR1,PSEN1,CIB3,SV2B,ATP1B1,VPS54,F2,CCR2,STIM1,CCL19,SELENON,SLC25A27,FIS1 |
| 2.710e-02 | -3.61 | activation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0006919 | 74 | 30 | 18204 | 5365 |
S100A8,PPARG,NKX3-1,RPS27L,HSPE1,FASLG,PYCARD,KHDC1,FAM162A,NLRP1,ANP32B,MCL1,TNFSF15,IFT57,AIFM1,HSPD1,CRADD,BAK1,BAX,EGLN3,MIR15A,BAD,DAP,JAK2,TNF,BCL2L1,BOK,MUL1,SMAD3,BCL2A1 |
| 2.714e-02 | -3.61 | ZNF354A (zinc finger protein 354A) | protein interactions | 6940 | 39 | 17 | 19454 | 5460 |
SRSF4,RPL28,RPL17,RPS10,DYNLL1,LYAR,RPL3,RPL8,PPAN,RPLP0,MECP2,CBX3,LLPH,HDAC6,ZNF668,RPL26,CUL3 |
| 2.714e-02 | -3.61 | AQP9 (aquaporin 9) | protein interactions | 366 | 39 | 17 | 19454 | 5460 |
SLC38A7,FATE1,CTXN3,RAB6A,CCDC167,EMC6,FGFR1,RAB6B,HGS,ADCY3,SERINC1,TF,VDAC1,TMED9,RIGI,AIG1,PAEP |
| 2.714e-02 | -3.61 | ZNF747 (zinc finger protein 747) | protein interactions | 65988 | 39 | 17 | 19454 | 5460 |
CBX5,MNAT1,IL18,APPBP2,PSMG4,PTGDS,CYGB,RHOU,FBLN5,PSMG3,CBX3,LBR,GTF3C4,CUL3,SUFU,NOTCH2,MZB1 |
| 2.714e-02 | -3.61 | PIM2 (Pim-2 proto-oncogene, serine/threonine kinase) | protein interactions | 11040 | 39 | 17 | 19454 | 5460 |
SUB1,FBP1,FBXO7,TIMM13,NDUFB8,TNNI3K,HSP90AA1,HNRNPH3,PRCC,BAD,H2AZ1,CLK4,IGF1R,TOP1,SPPL3,DAPK1,ZNF821 |
| 2.714e-02 | -3.61 | Cct2 (chaperonin containing TCP1 subunit 2) | protein interactions | 12461 | 39 | 17 | 19454 | 5460 |
CCT5,ACTR1A,ACTR2,PDCL,DNAJC19,CCNF,CCT8,IGBP1,TNKS,BUB3,ACTB,TCP1,TUBB,DNAAF10,CDC20,CCT7,PDCD5 |
| 2.714e-02 | -3.61 | REC8 (REC8 meiotic recombination protein) | protein interactions | 9985 | 39 | 17 | 19454 | 5460 |
STUB1,CCNF,MAVS,CFDP1,UBE2I,BAG2,CLPB,RNF5,RAD21,USP13,CKS1B,CCNA2,H2BC11,MECP2,DNAJB6,ACACA,HAX1 |
| 2.722e-02 | -3.60 | SIAH1 (siah E3 ubiquitin protein ligase 1) | protein interactions | 6477 | 213 | 73 | 19454 | 5460 |
MOB3C,PHC1,CDK5R1,TUBA1A,RIGI,KGD4,TOLLIP,KLF10,KATNAL1,HNRNPA2B1,ZYX,MYD88,CDC23,CDKN1B,LANCL2,KCNJ10,UBE2D1,GAPDH,SIAH2,CTNNB1,COPS5,ZCCHC10,UBE2E2,TRIM8,PEG10,CACYBP,RAB33A,AASDHPPT,UBE2N,PIH1D1,SDCBP,LMNA,EIF3J,MX1,RPL27A,ZNF671,BCL6,OGDHL,PIAS1,SPATA4,PYGB,UBE2D3,UBE2K,RLIM,RAB33B,OPRK1,HCFC2,PML,TRIM23,UBE2E3,RBBP8,SYP,CAPG,BAG3,ZMAT3,PRPF31,NTAQ1,RUNX1,OPRM1,CUL3,UBE2V2,SIAH1,SNX3,TXN,MAB21L1,PTPMT1,UBE2I,PSMC5,INHA,TRIM27,TUBA1B,NECTIN2,CPSF1 |
| 2.722e-02 | -3.60 | ANKFY1 (ankyrin repeat and FYVE domain containing 1) | protein interactions | 51479 | 213 | 73 | 19454 | 5460 |
SNAP23,HAPSTR1,STX8,SSRP1,ACTN4,MAP1LC3B,SELENOF,STX12,TFRC,EZH2,VAMP2,XPO5,CD274,CAV1,STK3,SLAIN2,STX6,SLC38A2,SNX2,SNX1,CGAS,INA,TBC1D5,STK4,VPS26A,IFI16,CDC23,CBL,MUL1,RAB5A,CLK1,SPOPL,PML,DVL2,RPA3,GABARAP,STX7,STAU1,ARHGEF39,KDM1A,YKT6,UFL1,NEK2,EHD1,ARHGAP1,UBE2M,PCLAF,SLC12A2,FGFR1,CTBP1,AP1AR,RPA2,PHF21A,EIF2S2,VAMP3,VIRMA,SRPK2,SMURF1,ROCK1,SNX3,GGH,RACGAP1,DEPDC1B,ARHGAP21,ATG101,CUL3,APOBEC3B,MYC,SNX5,UBE2H,SLC38A1,EPHA2,RC3H2 |
| 2.723e-02 | -3.60 | regulation of lipid storage | biological process | GO:0010883 | 54 | 23 | 18204 | 5365 |
ITGAV,HILPDA,VSTM2A,PPARA,MIR146A,LEP,FBXW7,ABHD5,PPARG,FITM1,NR1H2,MIR144,NFKBIA,TNF,FITM2,APOC4,MIR34A,MIR10B,OSBPL8,EHD1,NFKB1,IL6,CD36 |
| 2.723e-02 | -3.60 | DIAPH1 (diaphanous related formin 1) | protein interactions | 1729 | 149 | 53 | 19454 | 5460 |
RHOG,AGR2,PDIA3,PSMD3,IL18,CDC5L,RAB35,TES,ILF2,PSMC3,RRM1,MAP1LC3B,KRAS,TTC4,HNRNPK,WASL,RNF20,RIGI,IMMP2L,PAX6,NAE1,NUDT5,BRCA1,RHOB,CALU,UBE2H,MYC,CDC16,H2BC9,TXN,ACTB,ROCK1,ESR2,VIRMA,CCNF,CDC7,MSN,MED23,LMNA,RPA2,MAP2K1,UBE2M,ARCN1,CDC42,CFTR,CERS2,UNC45A,BAP1,DVL2,RPA3,XRCC5,HSPA8,RNF113A |
| 2.726e-02 | -3.60 | cis-trans isomerase activity | molecular function | GO:0016859 | 45 | 20 | 18094 | 5411 |
AIPL1,FKBP1A,PPIA,AIP,PPIG,FKBP14,PPIL4,PPIB,PPIH,PPIC,FKBP4,PPID,FKBP8,PPIL3,PPWD1,DEGS1,PPIF,FKBP1B,FKBP10,FKBP2 |
| 2.727e-02 | -3.60 | MATN2 (matrilin 2) | protein interactions | 4147 | 102 | 38 | 19454 | 5460 |
TRIP4,RPL27,DHX9,RTCB,RPL3,TF,THRAP3,STAU1,KRAS,TTR,SGF29,CMAS,RPL28,MATN4,RPS14,MAP2K3,SERPINA3,HBB,PIK3CA,SERPINA1,NUFIP2,KLHL26,ATXN1L,RPL8,ALB,TRAF7,NELL2,RPL7,RPL10,VIRMA,HOMER1,RPL6,CUL3,NONO,KLHL22,HP,RPL24,RPL23 |
| 2.729e-02 | -3.60 | Complex I biogenesis | REACTOME pathways | R-HSA-6799198 | 51 | 23 | 10285 | 3229 |
NDUFV2,NDUFA5,NDUFB7,NDUFB10,NDUFAF2,NDUFAF3,NDUFS2,NDUFS6,NDUFB5,NDUFB8,NDUFB4,NDUFAF4,NDUFC2,NDUFB6,NDUFAF6,NDUFA2,TMEM126B,NDUFS3,NDUFA1,TIMMDC1,NDUFAB1,NDUFA12,NDUFS8 |
| 2.732e-02 | -3.60 | regulation of endothelial cell chemotaxis | biological process | GO:2001026 | 24 | 12 | 18204 | 5365 |
CXCL13,SEMA5A,MIR149,MIR16-1,VEGFA,MIR424,HSPB1,FGF16,FGFR1,MET,TMSB4X,FGF1 |
| 2.732e-02 | -3.60 | somatic recombination of immunoglobulin genes involved in immune response | biological process | GO:0002204 | 24 | 12 | 18204 | 5365 |
HSPD1,BCL6,FOXP3,STAT6,MSH6,RNF8,SWAP70,CCR6,NBN,BATF,EXOSC3,CD40LG |
| 2.732e-02 | -3.60 | regulation of bicellular tight junction assembly | biological process | GO:2000810 | 24 | 12 | 18204 | 5365 |
CLDN3,SNAI2,ROCK1,F11R,CLDN1,TNF,EPHA2,GPBAR1,IKBKB,MIR105-1,MIR142,ROCK2 |
| 2.732e-02 | -3.60 | negative regulation of membrane permeability | biological process | GO:1905709 | 24 | 12 | 18204 | 5365 |
MIR17,GCLC,BOK,IER3,BAK1,SLC25A4,TMEM14A,MIR146A,SLC25A31,SLC35F6,SLC25A5,ACAA2 |
| 2.732e-02 | -3.60 | regulation of ubiquitin protein ligase activity | biological process | GO:1904666 | 24 | 12 | 18204 | 5365 |
PTEN,SKP1,RPS7,CDKN1B,MAD2L1,MAD2L2,RPL23,FZR1,CDC20,RBCK1,BAG2,UBE2S |
| 2.732e-02 | -3.60 | positive regulation of glial cell proliferation | biological process | GO:0060252 | 24 | 12 | 18204 | 5365 |
VEGFC,UFL1,LTA,IL6,PPP1CC,MIR221,MECP2,IL1B,MIR222,TSPO,KRAS,TNF |
| 2.732e-02 | -3.60 | isotype switching | biological process | GO:0045190 | 24 | 12 | 18204 | 5365 |
HSPD1,BCL6,FOXP3,EXOSC3,BATF,NBN,CD40LG,RNF8,STAT6,MSH6,SWAP70,CCR6 |
| 2.732e-02 | -3.60 | regulation of cellular response to oxidative stress | biological process | GO:1900407 | 24 | 12 | 18204 | 5365 |
HDAC6,CD36,FUT8,PNPLA8,TBC1D24,SLC25A14,FBLN5,MIR21,NFE2L2,SLC7A11,FADS2,MIR132 |
| 2.736e-02 | -3.60 | DNA replication factor C complex | cellular component | GO:0005663 | 5 | 4 | 19108 | 5553 |
RFC5,RFC4,RFC3,RFC2 |
| 2.736e-02 | -3.60 | synaptobrevin 2-SNAP-25-syntaxin-1a complex | cellular component | GO:0070044 | 5 | 4 | 19108 | 5553 |
STX1A,SNAP25,NAPA,VAMP2 |
| 2.736e-02 | -3.60 | mCRD-mediated mRNA stability complex | cellular component | GO:0106002 | 5 | 4 | 19108 | 5553 |
SYNCRIP,PAIP1,PABPC1,HNRNPD |
| 2.736e-02 | -3.60 | NatA complex | cellular component | GO:0031415 | 5 | 4 | 19108 | 5553 |
NAA50,NAA15,NAA11,NAA16 |
| 2.736e-02 | -3.60 | R2TP complex | cellular component | GO:0097255 | 5 | 4 | 19108 | 5553 |
RUVBL2,RUVBL1,RPAP3,PIH1D1 |
| 2.736e-02 | -3.60 | lipopolysaccharide receptor complex | cellular component | GO:0046696 | 5 | 4 | 19108 | 5553 |
LY96,TLR4,CD14,HSPD1 |
| 2.736e-02 | -3.60 | signal peptidase complex | cellular component | GO:0005787 | 5 | 4 | 19108 | 5553 |
SEC11A,SPCS1,SPCS2,SPCS3 |
| 2.751e-02 | -3.59 | DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10) | protein interactions | 54431 | 239 | 81 | 19454 | 5460 |
CTSB,FBXO22,SMURF1,APEX1,DUSP10,VDAC2,CCNF,FBLN5,ZMYM2,GANAB,SEC61B,PTEN,BRCA1,NTRK3,CALU,UBE2H,MYC,APOBEC3B,CUL2,CUL3,TOMM40,MAP3K21,EMC1,POLDIP2,HSPA5,DNAJC3,RPA3,TMEM106B,TXNL1,SQSTM1,AKAP1,RNF113A,P3H1,RPA2,LMNA,PPT1,HSP90B1,HEXIM1,PIH1D1,TOMM22,CDC42,EDEM3,DCUN1D1,PCSK9,CAND1,LMAN1,EFNA3,PRCC,COX4I1,PHB1,LDLR,RB1CC1,USP15,CALR,MAPK4,PDIA3,IFI16,ATG9A,DPP4,EDEM1,FAM20C,HNRNPA1,COPS5,PPIB,HSPB8,LAMB2,NEDD8,DNAJC30,PRDX4,ERO1A,IGF1R,PDIA6,ERP29,RPN1,SFTPC,SELENOF,TRAPPC13,GNB1L,PLD3,CSNK1E,OTUD6B |
| 2.751e-02 | -3.59 | EAF1 (ELL associated factor 1) | protein interactions | 85403 | 127 | 46 | 19454 | 5460 |
RAP1B,HOMER3,SRP14,CDK9,TOP1,CCAR2,GAS8,XPO1,DNTTIP1,BRD3,RSBN1L,NOS1AP,PICK1,TCEA2,TFPT,PAX6,ZBTB14,CAMKV,KRAS,TRAF2,ASPM,TRIM62,TAF1D,NFKBIL1,TFCP2,TNNI1,GTF2F1,AP2M1,RBMX2,EAF2,DYRK1A,CEP70,MCM3,GPRASP3,STAC3,TNFAIP8,PIP4K2C,YAF2,HDAC3,CPSF4,GTF2H4,LUC7L3,PIH1D1,RPL26L1,MFAP1,SDCBP |
| 2.751e-02 | -3.59 | TUBA3C (tubulin alpha 3c) | protein interactions | 7278 | 127 | 46 | 19454 | 5460 |
G3BP1,TCP11L2,UBL4A,CHRM3,TUBA1A,FAF2,TUBB4B,SKA3,TFCP2,PPP4C,SSBP1,FEZ1,ARL4D,KLHL9,ZNF24,RBM17,PFDN5,ROGDI,CD81,YWHAG,GLO1,TUBG1,YWHAB,PML,UCHL3,HMGB1,RLN2,KLRD1,DYRK2,RETREG3,GPN2,PTEN,MTM1,SIAH1,GARIN2,DYNLL1,LAMTOR3,ESR2,NMI,MYC,CUL3,CEP70,CCT2,CHTOP,YWHAZ,ANAPC4 |
| 2.751e-02 | -3.59 | TELO2 (telomere maintenance 2) | protein interactions | 9894 | 127 | 46 | 19454 | 5460 |
APLNR,PSMD6,PTPMT1,CCNF,LMBR1L,RIT1,AR,CUL3,NPTN,IRF3,RPA3,PIH1D1,TTI2,RPA2,NPY2R,CDC42,TANK,ELK1,EGLN3,EEF1AKMT3,CD274,AIFM1,TOPBP1,HAX1,DNAJC7,PEX3,SMAD4,AK2,SLC2A1,P2RY10,XPO1,FAM174A,UBXN6,DNAAF10,RUVBL1,RPAP3,RUVBL2,GARRE1,PLD3,CRKL,AQP3,VPS33A,TULP3,MGARP,CHRM3,B3GNT2 |
| 2.762e-02 | -3.59 | FTH1 (ferritin heavy chain 1) | protein interactions | 2495 | 165 | 58 | 19454 | 5460 |
VIRMA,TAX1BP1,YES1,MATR3,STAT1,RPS12,CALML5,CSNK2B,DLG4,OPTN,KLK5,CRMP1,RAP2C,NTAQ1,BTF3,CDC16,MYC,SMARCA5,AZGP1,FTL,TICAM2,RP2,FXR2,RAP2A,LCP1,NR1I3,HADHA,SQSTM1,NLE1,PRKCA,PPT1,GPR35,SDCBP,FTH1,CFTR,CDC42,ARHGAP1,PAIP1,HSPB1,SPP1,LAMTOR2,FLOT1,AP1M1,KPNA2,TOLLIP,TRIM37,DHX16,SEMG2,PPP1R12A,SDR16C5,MSRB3,AP1S2,MAP1LC3B,GABARAPL1,TP53,E2F4,RAF1,MAX |
| 2.763e-02 | -3.59 | PBD | pfam domains | PF00786 | 14 | 8 | 17795 | 5224 |
PAK5,CDC42EP4,CDC42EP3,WASL,PAK2,CDC42SE2,PAK6,CDC42EP2 |
| 2.767e-02 | -3.59 | MIR19A (microRNA 19a) | protein interactions | 406979 | 99 | 37 | 19454 | 5460 |
HNRNPA1,NONO,TRA2A,CPSF2,KARS1,APOBEC3B,WWP2,DDX1,IGF2BP1,CRTAP,SF3B4,CPSF1,SYNCRIP,EIF2AK2,CSTF3,MATR3,FAM98A,HNRNPL,RBMS2,CPSF4,STRBP,RBFOX2,HNRNPH3,RARS1,NUFIP2,P3H1,WWP1,HNRNPH2,SF3B1,RTCB,HNRNPA2B1,G3BP2,MARS1,HNRNPF,TRA2B,HNRNPA0,HNRNPK |
| 2.773e-02 | -3.59 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | biological process | GO:0051897 | 185 | 67 | 18204 | 5365 |
OSBPL8,MIR29A,MYORG,CD28,RAMP3,VAV2,TPBG,JAK2,HCLS1,CHI3L1,C1QTNF1,AKR1C2,MIR21,HBEGF,NTRK2,CCL19,F2,BECN1,NTRK3,GRM2,CPNE1,SOX9,KIT,NDP,OSM,CBL,SESN2,RTN4,CCL21,DDR1,HCST,PHB1,GPX1,CDC42,TXN,CX3CR1,PIK3AP1,IGF1R,MIR126,GH1,P2RY12,FERMT2,UBE3A,MIR675,CX3CL1,TGFB2,FGR,PIK3CA,CCL5,TNF,TMEM100,IGF1,STK3,LEP,MTDH,PIK3CG,PRR5L,CCR7,NKX3-1,HAX1,RGL2,SEMA5A,ANGPT1,SRC,IL18,CCL3,FGFR1 |
| 2.778e-02 | -3.58 | SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | REACTOME pathways | R-HSA-77588 | 11 | 7 | 10285 | 3229 |
SNRPD3,NCBP2,ZNF473,LSM10,SNRPG,SNRPB,SNRPE |
| 2.782e-02 | -3.58 | VCPIP1 (valosin containing protein interacting protein 1) | protein interactions | 80124 | 146 | 52 | 19454 | 5460 |
SSX2IP,SMAD9,YWHAH,CTNNB1,EDC3,MOV10,UBXN6,GSTM3,MDM2,PTP4A3,SVIP,OLFM2,MCL1,STX5,ARL4D,EEF1AKMT3,VPS33A,PLAAT5,UBXN2B,FAF2,VPS16,HUWE1,TRIM37,FAF1,MAF1,FBXO7,UFD1,GGH,MAT2A,SFN,FCHSD2,VIRMA,ACTB,GSK3A,LMBR1L,NFKBIB,TUBA1B,RPA2,VAV2,MED23,CNPY3,PRMT2,RFXANK,EDEM3,PXMP2,RNF41,SNX24,KDM1A,NSFL1C,DCTN3,RPA3,CNKSR3 |
| 2.786e-02 | -3.58 | liver | COSMIC cancer mutations | liver | 16100 | 4649 | 16828 | 4835 |
INPPL1,ING5,MIA2,BACH1,KIF2A,SLC35A2,ENTPD4,ARMC8,PTDSS1,ID1,POU1F1,CYC1,CCDC42,NPTN,FCAR,CRYBA2,DEGS1,NLGN2,DEK,SLC5A6,CYP4F8,PRKD3,SPEF1,OR52M1,NUP107,SCAMP2,CD164,BPGM,PPIB,MRPS25,RBCK1,NFE2L1,AKR1A1,NOP58,SPATS2L,MRGPRX4,FABP5,CTSD,PGAP2,URM1,CETN3,CTSK,CACYBP,RAB3C,MTAP,PWP2,TGFB1I1,DUSP1,BATF,TOLLIP,STX8,S100A10,NFYA,CPT2,CHST9,ANP32B,AP1G2,NDNF,DCAF8L2,OTUD6B,SETD4,LCN6,FBXO9,COX7A1,WFDC13,ACOT13,TMED3,OR2W1,RPGRIP1L,CCND1,KLF10,S100PBP,MRPL47,TMEM33,MPHOSPH10,AP3S2,ARHGAP21,SCG2,SPINK13,RHCG,FAF2,BMPR1A,PROX1,PRKX,FGF13,ZMAT5,RTP4,LSM6,SYNGR1,NAB1,ENPEP,VPS4A,USP39,CERK,SLPI,USP38,ZNF174,CWF19L1,CDK6,DCAF5,ESR2,FAM13B,SNRPD2,ADCY3,CLEC12B,OAZ2,SFTPD,SOCS2,INTS12,CYP2D6,CTNNB1,RAB8B,TNFAIP3,ABHD16B,MTMR12,DUOXA2,MMACHC,TRAF7,IQSEC1,NOL4,FYTTD1,SIRT7,ETV6,TAPBPL,H19,SPRED1,NONO,POLL,TSSC4,ALDH1L1,MAK16,EIF4EBP2,OR2A2,HPCA,SV2B,ZNF805,TCP11L1,SOST,NDUFAF2,GPR37L1,SNTA1,SNAPC1,GFOD1,SIVA1,BRMS1,PAOX,CD3G,CHRNA7,KIF1C,GAS8,CDKL2,LMBR1L,NPVF,AKR1C2,IGFBP4,TAC1,OPA3,TBCE,SPATA2L,NQO1,IPP,OXNAD1,BRI3,ADAT1,OCEL1,HEXA,TMED1,RBM23,HBB,FGF17,NEDD8,CXCR1,PTCRA,TRMT6,NDUFA5,CCL21,KCND2,IL34,DFFA,RASGRP2,LPXN,ST13,CD2,POLR2I,FBXO30,TIGD7,WWP2,RABAC1,UCKL1,ACAA2,RAP1A,PDIA3,FRA10AC1,XPOT,CXCL1,ISYNA1,NDUFB8,APH1A,EIF1AD,NAA11,LEPR,STX17,WNT7A,MSX2,NLE1,KRR1,SNAI3,CDC37L1,PELI3,PGBD2,STAMBPL1,SIPA1L1,ZKSCAN1,CLDN14,HSPE1,RPL37A,SERPINH1,RAB4A,SOX21,TRA2B,DHX16,LEAP2,HADHA,LHFPL1,B4GALT6,HSPB1,KCNA2,GXYLT1,OR6M1,NUDT16,GALE,SH3GLB2,EIF2B5,CIRBP,ANKIB1,ENDOD1,OSR2,CXXC5,MOB3C,LASP1,PHKG1,SPOCK1,NEK7,UTS2R,GTF2A1,WBP2,FUT8,GNMT,CCL25,CREBL2,TXNIP,AQP4,GLE1,WDR37,EIF4EBP3,OR51S1,ZSCAN1,SLC39A9,DHX9,FURIN,PSMD6,IL23A,SLC20A2,PCDHA5,UBXN10,LDHA,NUBP2,PRCC,GSK3A,ABCC5,THOC1,NUDT19,RC3H2,FATE1,ATP2C1,DNAL4,XPO1,EXOC2,GJA10,SLC25A32,EFHC1,THRAP3,EEF2,RNF103,CREB3,TF,INTS10,SURF4,XPO5,RNF187,GPR162,APOBEC3C,ZNF513,SLC7A4,ZMYND11,TXNRD3,SETD5,HNRNPC,PTPN1,ZBTB38,TRIM37,HECW1,PGS1,RBBP7,SLC25A21,RMND5B,ARMCX2,ACTA2,SIX5,TRIM21,PPARG,ARFIP1,GALNT12,SPR,FRMD8,RFX4,ZDHHC14,ADRB1,PKNOX1,PCDHB8,RBM17,HEY2,TRAPPC1,PAEP,NIPA2,RABL2B,CLDN11,FAM199X,NPY2R,LRP12,RNASET2,SPTAN1,SLC35E3,CAMK2G,BUD31,TMX4,SRP54,CIB3,TACR3,PRMT2,CACNB4,RPL15,TUBG1,GHITM,TTC4,SCFD1,CCDC47,SHC1,PYGM,OR4K1,FGFR1,CAMK2N1,KCNJ11,CRYGB,PPP3CA,CD200R1,CCDC127,PEX3,RCVRN,SLC39A7,SORD,SBK2,MCOLN1,PSMB5,ENPP4,CCT5,AGK,FBXO32,ANAPC2,PRPF4,ARMCX5,ZNF593,RAB18,IDH2,FKBP14,CD58,AGER,IMPACT,KPNA1,PIWIL4,CSNK2A1,RARRES2,GRSF1,ATF4,GNG7,CTNNBIP1,GSTO2,KBTBD2,SUPT7L,JOSD1,P4HA2,AFTPH,LSM3,KIT,RS1,LHX2,ZYX,UBAP1,CDC73,CYP27A1,S100A6,DYNC1I2,BTF3,MMP9,ROPN1B,VRK1,PGK1,ALKBH4,PACSIN3,HEBP1,SLC7A9,SNAP91,MYH2,DNAJC5,TMIGD1,ATP6V1G1,MTPN,WDR77,FZD4,MEST,AAMP,GPBP1L1,TMEM213,MX2,ZCCHC10,SYN3,MFSD6L,LYG2,ZNF24,TMEM215,FBXO42,TSEN54,SERPINB10,AZIN1,PSME2,HBE1,AZGP1,INO80C,ABCB1,FGF1,JAK1,LBH,GTF2E2,MAGOH,TBC1D10C,CCL19,NKX3-2,DHRS3,TNFAIP8L2,DEFB116,NDST1,DNAL1,KTI12,SMAP2,RAB3B,CDCA3,PYDC2,CYP11B1,GRM2,CTNNBL1,IDH3B,GALNT4,SENP5,GPAA1,ADGB,JAKMIP1,TLR3,ITK,EIF4H,NCR3,FAM8A1,LRRC69,SWAP70,CYP39A1,HSD11B1,MYL12A,GNRH2,CHDH,HSBP1,DHRS4,SLC35A1,IMMP2L,MEF2A,RAG1,ENY2,SLC30A5,KLK3,SNAPIN,ZNF304,MRPL50,MRPL24,IL15RA,OSM,SLC38A9,MIOS,PPP1R2,FAM78A,RMND1,ARMCX1,UBE2A,CHRM4,CCT2,UBE2D3,ATP6V0E1,NHP2,TRIM23,NAIF1,OR8B8,IRF1,STRBP,ING1,P2RY1,CASK,GAL3ST1,OR4D11,LTBR,ELMO1,TCP11L2,GRPEL1,PRPSAP1,GABARAP,FGFR1OP2,CDK5R1,NRP1,NCKAP1,CNIH4,GLUL,LMO4,ATPAF2,KIAA0232,CLU,CCR6,TAAR1,SLAMF9,ZMYND19,XAGE5,APOBEC3A,ZNF397,ID4,SEC14L1,ZNF319,ZNF207,EDF1,ATP6V0B,TMEM219,C1QC,TRIM3,TMUB1,ZNF671,SLC25A31,SLC17A5,RPS14,LIG3,LYPLA1,MEAF6,UGCG,PLA2G5,KLK9,DOK4,ARHGAP1,RNF141,KLHDC8B,TRIM32,CD99L2,SNRNP27,PRIM2,SDR42E1,PDIA6,UBR7,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,E2F6,GFM2,GDI2,MRPL23,PSMA3,CCDC69,GALNT1,SOCS5,AK2,GSTO1,TMEM156,SPRN,EHBP1,MGP,MDM2,MRPL13,PFDN5,EXOC8,UST,GNRHR2,TOM1L2,LYAR,B9D1,NUDT3,CNP,RND3,SF3B4,IL20RB,DKK3,CRABP2,PRRC2A,DPP10,CDO1,PPIL4,RAB11A,CCNI,ASMT,TLR9,L1CAM,FIBIN,WDR38,SNX20,DLX1,AKT1,APEH,FGD2,FNDC8,COMTD1,SLC35D1,SMU1,RMI2,COL1A2,SAT1,CSGALNACT1,R3HCC1,METTL14,VAMP5,GNG2,EDEM1,JPH4,AMIGO1,TOR2A,PTS,MAP3K11,GTF2H2,MBL2,ADIPOQ,ANKRA2,ERH,ALKBH5,UHMK1,LCP2,CRTAP,IK,ABHD6,CLDN1,METTL2A,TFCP2,AKAP14,NDUFAF4,CRYBB2,FAM162A,CTDSP1,CCNB1,GPX6,POPDC2,GREM2,TGIF2,RDH10,GPAM,PDCD4,LDOC1,CREBBP,PRPF19,OR4Q3,HTR1F,TRIM54,RPLP2,CDC42SE2,ACBD7,FAM98A,KDM4B,TMEM184B,ZNF287,ACAT1,GIT2,OAS1,NKIRAS1,CXCL3,GTF2B,RUVBL1,SDF2L1,RAB3D,LAMB2,SLC13A5,APOO,SNX17,BCS1L,GPR137,NRSN2,SRRM5,TMEM144,TOP1,GCNT3,OPRK1,NKX3-1,F9,ZNF740,NDUFS8,CYP2C18,MYO6,TEX30,SEC61B,GPR65,BCL7B,TOM1,DNAJC22,EIF2B3,TMX3,HTR5A,TCF23,PAPSS2,GBE1,CHGA,MRPS23,FUNDC2,CSRNP1,ATG4A,SYP,ZNF862,SFRP4,RGS7BP,CDKN2AIP,FCN2,RER1,ISG20L2,GPHN,POLE4,HSP90AB1,ARMC7,CIDEB,IPO8,ZBTB5,ZC3H7A,CCR2,DSTYK,TMEM123,BZW2,OR10G9,TSPAN5,RINT1,NAT2,KHDC1,SPECC1L,B3GALNT1,CREB3L4,EIF3K,CD274,FABP7,ZBTB17,BCAP29,DDX39A,IGBP1,AKAP12,SSU72,BLOC1S2,SNCG,SNAPC3,COX4I2,CDKN2C,LHFPL4,CALHM3,TRIM5,EIF4E,GOLGA7B,OLFML3,TSPO2,SH3GLB1,PREPL,THTPA,RNF113A,EFNB1,IFNA10,DEFB114,MT1M,TFE3,COMMD8,ITGA6,CSNK1A1,PELP1,HOXD12,ADIG,RTKN,NTN4,FUT9,PHYH,IL10,UBE2V2,RPLP0,CALHM2,ADO,GMPPB,BECN1,LMNB1,CCDC25,TES,CHMP2A,OSTM1,EMP3,MSMP,HSPA8,VMP1,CBR4,SLC19A2,EWSR1,B9D2,TMEM204,PROS1,GPX3,MRPS16,ABHD14B,EED,MTRF1,ZNF592,ACSL4,DTYMK,TGFB3,TRIM24,CIB2,ELP3,NOS1AP,BCL10,KCNMA1,MBD5,PDHA1,ADPRH,DUSP19,NME1,STMN2,RGS2,DPY30,CNNM4,NR1I2,CDK4,NPR2,TRAF2,RBM7,KCNK13,ABHD4,PCDHB1,BRCA1,STAU1,STOML3,TSN,SLC41A3,SERINC3,KLK6,FKTN,RNASEH1,DNAJC3,TMED7,IL18,DERL1,ST3GAL1,CSNK1A1L,SOX2,KLC2,PAX9,STXBP1,PCMTD2,STOX2,ERV3-1,IRF3,MTHFD2L,CD36,UQCRH,DPEP1,PRKAB1,NDUFB4,RAC2,LCA5,STK24,PYROXD2,MRPS21,TAS2R40,LRP6,PARP11,SLC32A1,FAM163B,POR,ST3GAL5,IFRD2,CEP97,ZNF501,ZCCHC9,SLC43A2,TMEM91,CASP12,TEX12,B3GNT2,TOP3B,FLYWCH2,LRRC24,GRIA2,MRGPRX2,DDX4,LIX1,KLK5,GDE1,TCEAL7,TMEM14A,GPX5,TRIQK,PCGF3,CDH8,CPSF2,MYEF2,PNPLA8,MOV10,UQCR11,NGB,GLT8D1,SOS2,PIWIL2,AKIP1,SLC23A2,GYS1,PGM2L1,ROGDI,CDKN1A,GK2,FOXN2,RBFOX2,ELSPBP1,ORAI3,STX18,SLITRK2,MED11,CLIC2,SDHAF2,PPFIA3,OTUD7B,AMY2B,RBMX2,NDE1,CD2BP2,TDRD7,HMBS,SELENOV,LDHAL6B,CCDC65,SNIP1,SLC4A8,LY6G5C,UBE2D1,ACTL6B,FAM168A,RAB1B,RPAP2,RGS5,INHA,OR5L1,ZBTB45,ABHD13,HRH3,TXNL1,DERL2,MLF2,ELMOD1,LYNX1,RPL23A,IL6ST,TMEM59,EIF4B,PPP2R1A,SMAD3,SLC25A4,PTHLH,MRTO4,SELENOK,STK38,TIMM10,WEE2,PCDH19,PNP,RAB5C,SMN1,AP1AR,FOLR1,SLC6A11,RAB37,C1QL1,FBXO25,IFI35,PSRC1,CSTF2T,CAV2,SACM1L,VPS33A,CD226,CRBN,ZFP1,PDYN,B4GALT3,CMPK1,SNRPA,BEND5,CCNF,VAMP2,TRAPPC6B,GPIHBP1,WDR44,CTNNA1,RAB2A,PHYHIP,DYRK1B,WIF1,FN3KRP,SNX24,ACADSB,OR10G7,STAT6,FGFBP2,ARCN1,EZH2,INPP4A,KCNIP3,AMT,RAB9B,PRKAG1,HNRNPK,PAFAH1B3,NFKB1,SCD5,MAFG,ACAP2,LHFPL2,FOS,DYRK2,EGLN3,CLDN22,OS9,RPL26,POMP,OAT,MRPS28,RIOK2,CCL8,NAA60,RB1CC1,CAPZA2,SLC35E1,TPPP,RFTN2,PPID,YPEL5,ATP6V1C1,GGCT,RCBTB1,HNRNPA2B1,TAPBP,MAPK1IP1L,PLA2G15,FANCG,STX6,OR2A25,WWP1,RHOJ,CBLN4,CD47,S100A8,HIRA,JUN,IFNG,TMEM50B,ZNF687,OGG1,CCR3,SUMO3,OPHN1,PTGER1,CMAS,RAB23,SFT2D2,DNAJC8,PPDPF,TNFSF18,FAM107A,RNF167,CRYGD,RAB33A,SPTBN1,TNRC6C,RNASEL,CHI3L1,UTP23,GNPNAT1,GIMAP2,FERMT2,TOMM40L,EIF3J,PLAGL1,PAPOLB,SESN2,TRAM1L1,RFXANK,KLHL15,GCA,ZNF576,RABL3,ISCA2,UPF3B,EHD1,MPV17,CHST1,FCHO2,TRAM2,PPP1CB,SLCO1A2,KCNK10,ZNF609,TMCC2,SELENOS,MANSC1,GJB2,WDR3,KRT7,PLEKHA8,TMEM106C,SRP14,NUS1,ACTR2,TMEM203,TAS2R5,FOXS1,PTRH2,OR4F6,CRYBB3,APLN,TMEM164,SYNJ2BP,ACP6,KIAA0408,RNF122,NAPG,SERPINA5,BICD2,TMEM177,FMO2,GLIPR1,SQSTM1,RBM12,RAN,RPP25,BRD9,HAND2,PGR,POLR3B,NPY5R,CDH13,HSPA14,CXCR4,DLG4,GTF2F2,OR2H2,CCL17,KIAA1191,KCNH1,SLC7A14,DDX42,PXMP2,ATP1A2,PPP1R16A,CYB561D2,GMPPA,RPL6,SPRR1B,TUSC3,CXCL14,ADAMTS1,CLDN8,BNIP3L,CLDN3,ADAM21,RLIM,PTEN,DEPDC1B,INO80E,CRLF3,UCN,MGAT5B,PTAR1,THAP7,UAP1,TXNDC12,RWDD3,CENPW,ATG4C,SNRNP48,FRRS1,GFPT1,SDHB,NEGR1,SIT1,FDFT1,CCDC160,MOXD1,EPHX1,ABHD5,CXCL13,CKS2,NRN1,MAPRE1,TMA7,MUL1,SMG9,SEC22C,MME,METAP2,ZFAND2A,ELMOD2,OR10A4,USP15,FKRP,LPAR2,CNRIP1,APOBEC3G,NTRK2,PABPC1,GNG12,DNAJB9,ARG2,RNF144B,SIAE,GAMT,ISX,GLRX5,RTN4,GNAZ,NXT2,HNRNPA0,CHST2,IKZF5,FZD3,CD247,RHOBTB1,CDAN1,OPRM1,SPRED2,DDX23,PCNA,PIK3R2,PDE1B,UBE2K,NDUFS6,TMEM126B,CTSC,CREG2,PCYOX1L,PLD3,AGPAT5,DNTTIP1,HR,ARPC3,DKC1,FBXO44,PPFIA2,CNDP2,FBXW11,CINP,BCL7C,IL1A,OR4D6,THBD,HTRA2,NDUFAB1,JAGN1,SNAP29,TYW5,CBLN2,NUDT12,RPL27A,NEUROD2,BABAM1,METTL15,PGRMC1,PTK7,COX20,DHX38,GPR171,COX8A,LGALS8,TMEM147,USP8,IRAK4,IMP3,UBL3,TMEM30A,AFAP1L2,B3GALT1,COMMD6,KCNJ3,GNPDA1,SFXN2,SNX22,FASTKD5,CST11,NCDN,CYP21A2,GNAO1,NDUFB6,TMEM170B,TMEM117,GLRX,TOR3A,CBLL1,UBA3,SRSF7,EPCAM,PCDH17,TAGLN3,SAV1,STAT2,IL22,PRR3,HENMT1,RPL7L1,CSTF3,CSGALNACT2,ST6GAL1,REEP3,BFAR,TMEM179B,LARP4B,OR2Y1,STX11,SERPINA1,PMP22,TMEM254,SCLT1,MRPL11,DAAM1,LRRTM3,ANKRD34B,LSM10,HSPA13,NPSR1,LMAN1,PPP2R5E,SH2D1A,UBB,SLC11A2,FBXL14,RHEB,DHX15,OVOL1,NPPC,PSMD4,RPS7,GRAP2,RAB27A,GPX1,RELL2,TRIM15,SLC6A6,SLC30A7,TCF19,CCDC134,DDX46,PDHB,MLC1,ZNF664,MAT2B,OCRL,XCL1,BBS5,GANAB,RPS6KA4,TSPAN18,METTL21A,POP5,G3BP1,CHAC2,MFSD5,FGFBP1,MRPL18,HINT2,TMEM101,NUF2,OR13C8,SLC16A1,PCDHB13,RPS27A,DSTN,DAPK3,RAPGEF5,DBT,ELOVL7,TPD52,SUFU,MTA2,CCDC86,MRGPRX3,LAPTM4A,FBXL19,CHIC2,CHCHD4,SLC38A7,PGGT1B,KCNC1,OXTR,OXSR1,ILF2,ORC5,ZNF365,BAG3,KDELR1,TOM1L1,RRM1,RBM22,RPS16,KRAS,CNTN2,ASNSD1,NR2F6,DKK1,HERC4,PSMB1,CRIP1,ZMYM3,NDUFAF3,CHPF2,IER2,RND2,PPP1R1B,BMPR2,COMMD3,SCG3,OLFM3,RASD1,CCS,ILDR1,NLRP3,SCGB1D1,SHISAL2B,CHKB,CCNY,ELF5,CLDN12,GPR176,PKP4,SCML2,DNAJC19,VGLL4,FCGR1A,GSTM5,ERAS,MYBL2,PLEKHO1,ZNF326,CRHBP,CNOT2,OTOS,ODAM,FEN1,CLPB,VDAC1,KLF1,PRKACB,ASB7,GLRX2,LANCL2,APOBEC3H,ADD1,JKAMP,CBR3,SEPHS2,CLEC2B,MCM4,SCNM1,DCTD,FAM177A1,STARD4,THOC2,ORC6,FLOT1,NR2E1,DROSHA,KLHL22,MAVS,UBP1,IGF1R,CX3CR1,SLCO2B1,PDAP1,SOX14,CEP19,CHMP4C,CDCA7L,MRPL22,SS18,CD1C,RAB19,UMPS,NUDT7,IFIH1,BIRC2,MTM1,EPS8,RFXAP,UPK1A,HOXC4,SIAH2,CHCHD6,POLR1B,CER1,TIMP3,PPP3R2,PRSS12,PRMT6,PMM2,TMEM70,MPDU1,VAMP8,PPAN,IL2RA,RCL1,KLHL24,GABPA,FKBP8,PPP2CB,CHST13,ZNRF1,CLEC18A,AQP2,SMAD1,SPC24,HP,CTTN,STOM,CLLU1,RPL23,SPIN3,ANP32A,RABGGTB,FBXO7,SLC2A3,SEMA4C,METTL22,CYP2C8,ASZ1,CAPN1,USP3,TGFBR2,CEBPG,CDNF,TNFRSF1B,LAMP2,TMEM237,RNASE1,CGB8,TMEM45A,FAM43A,NLRP9,LLPH,GSTP1,CCL2,OR8B12,PPM1K,AR,IFI6,EFNA3,TPM3,SNRPB,MORC2,ELOVL1,SSR2,SOSTDC1,OR10P1,RIT1,GPX7,CHRNB2,PTPN4,TMEM167B,HSD17B6,MAP2K1,PLCB2,APOBEC3F,FPGT,LRRC3B,OTX2,EIF4A2,PRDM4,FEZ1,STAT5A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IM11,C1QL3,PROM1,QPCTL,RBM18,TOPBP1,MTG1,RPL3,GLRA1,G2E3,E2F4,FCF1,MRPL52,MYD88,CD1D,GLYAT,GFI1,TMEM209,FLRT2,DEDD,BOLA3,PPM1G,CDC42EP2,ATP1A1,CRKL,TGIF2LX,B4GALT1,STARD13,AOX1,PSMA5,DNAJB6,ZFAND2B,KDSR,CD1B,GCC1,LRRN1,DNAJC27,RP2,CENPP,STX12,FBP1,TMEM199,GZMK,CNPPD1,NLRP1,GSTK1,NAE1,RPS11,GTPBP1,KCNMB2,TMOD1,TXNRD1,KATNAL1,AZI2,ILVBL,ARL15,EGFL8,DNAJC25,NDUFA12,NUDT5,UBN1,TPSG1,UBE2F,FOXP2,CYP17A1,SLC22A12,SNAPC2,CCHCR1,RPS5,SLC1A1,PDE9A,CCDC71,CYTH1,DDX5,EIF4A3,ADNP,LAMTOR1,RAP2C,DNAJC10,RGMA,RAF1,IRF6,GPNMB,SAT2,PRRG1,GTF3C3,RNF14,CSTB,KLHL7,MCHR2,ZNF330,DET1,OR51A4,SCYL2,RPL10L,COG1,PHKA1,ALG2,MBLAC2,FUT1,DOHH,BAP1,PLAA,RPRM,GPR26,IL1B,SYS1,ARL4A,ARFGAP3,LITAF,LRRC4,DRAP1,MEF2C,ELAVL4,RPS27L,SEC61A2,STK11,TESK2,COMT,GOLPH3L,TNNT2,GPSM3,TP53INP2,LAMTOR3,ZNF175,SNRPD3,SEC62,FGF12,RIMKLA,EXOC1,GPX4,PHAX,FKBP10,BAALC,TMEM106A,ANGPTL2,LY6G6C,RHCE,RAB5A,PC,APOBEC3D,NEK2,ZNF526,NDUFV2,NDUFB7,F10,KCNA3,SSBP1,PTN,SP4,OR4N4,ZBED4,DYNLT3,WASL,CD79B,SDC4,GOLGA7,TMCC1,RAB14,BVES,CHRM1,MSX1,IL3,DLG1,P2RY11,TLR6,RPN1,CD151,KCTD9,STAT1,ZNF507,PAX6,LMBRD2,MRPS33,LMO3,UGP2,EIF2S1,HEXIM1,DPP4,PRDX2,DRG2,THBS3,CALR,TRUB1,SNAI2,TSG101,MAMDC2,ADCY2,PKIG,MOBP,OAF,HEXB,SYNGR4,PPFIBP1,CYTL1,NDUFA4,SLC45A3,SHMT1,ODC1,SLC25A23,DSN1,ZC3H15,SFTPC,SLC6A4,PDSS2,YIPF5,TOB2,FNTB,NME4,CDK5,GNG3,MRPL51,PATE2,RNF26,RAB13,OR10G2,SELENOF,MAP1LC3A,RPP21,SNAPC5,NDC80,CYB5R3,PLAC8,TPBG,KCNQ5,PDE1A,DAPK1,LILRA1,STXBP6,ZCCHC12,ARRDC3,EEF1G,LRWD1,SLC25A17,NFYB,PSMD14,TESC,YWHAB,THY1,ZNF692,SLC25A44,CDSN,SESN3,PHB2,MMADHC,TTC1,NR1H2,BMP1,PRPF31,LEPROTL1,TMEM95,SYT2,SPOPL,TBC1D24,ST6GALNAC3,EDNRA,ASB3,CHMP5,EIF2S2,ZMYM4,BTG1,AGPAT1,GNA14,CXCR6,CISH,TXNL4A,NANP,TSC22D3,USP14,DUSP26,EYA3,CNTNAP1,TMEM176A,HDAC6,PBLD,RNF39,MICB,TOR1AIP2,NUP153,STOML2,OTUD6A,PPARA,COPS7A,RNF20,ACTL9,GTF2A2,TPT1,SNCB,ATL1,RRAS2,RPL35,POLR3F,FRS3,RERG,OST4,STARD3NL,YWHAZ,ICAM2,ABHD8,OR8H3,SLC8A1,LSM14A,CAPN2,BOK,OR6X1,TNR,TM4SF18,SLC29A1,SURF2,GJA1,MAGED2,CCNA2,TM4SF20,RNF222,REEP4,AASDHPPT,MARVELD1,MAGEB10,CXCR3,HOMER3,TAF1D,KCNJ10,SHPRH,SLCO3A1,SPATA2,ADORA1,OR4K2,GRM1,PCGF6,FAM81A,CEND1,EHD4,ZNF511,STAMBP,HNRNPF,SLC25A1,GXYLT2,KCNJ2,CTU1,EPHA4,NPY1R,GCLC,PSMD10,CPLX3,TNNI3K,CITED1,LIAS,ARL4D,TXNDC17,CDK12,DLK2,PLG,DMTF1,TNFAIP6,FBXW7,PSMB7,ING2,ARL2BP,CHRM3,TSR2,SPP1,FRZB,FAM149B1,PRSS23,GPR17,GPC1,PLCB1,ZNHIT6,TNKS2,LILRA2,LY6H,HSPB2,COMMD9,STK3,CBLN1,DCAF12L2,PLSCR1,PTP4A3,CREBZF,PAQR3,JAK2,PROK1,MRPS18C,NT5DC1,TRIM36,GSTA2,TMEM127,HCAR1,MCL1,FAM53C,ALG11,NDUFA1,DDAH1,GPR35,HFE,CTXN3,ZBED1,DPH5,PNMA3,RB1,TRIM29,OIP5,CORO6,NDUFC2,TMEM205,TRIM34,RGL2,ITGB5,BLCAP,ICOS,NINJ1,CAV1,B4GALT4,RPS2,YIPF3,TCEAL8,LXN,EIF3G,MEPCE,CCIN,UBE2L3,TTPAL,PMAIP1,PDE4B,SPEM1,CYP3A43,CSNK1G3,RAB39B,MRPS11,AKR1C1,SREK1IP1,CNTROB,FTSJ1,ABHD10,HUWE1,CPLX2,PRND,TYROBP,NHEJ1,WDR11,SLC35B3,FHOD3,AIPL1,PEX13,NBN,VMAC,IL2,SEC13,WDR5B,ZDHHC4,CDC20,SNRPG,ADTRP,TIMP4,XRCC5,ACCS,SGMS1,RBBP8,MGAT4A,TRIM45,ATAD1,DUSP21,IGSF11,CYP2C9,MRPS34,CDC7,MPPED2,PRL,FBXO8,NDST3,OLR1,SLC19A3,NUDT9,CYGB,PPAT,IL17F,TNF,GGH,CCR4,CHRAC1,KLF3,LZTFL1,SNRPB2,TFB1M,SUMO2,CGGBP1,PHF13,RPL26L1,PARP2,NF2,ABHD12,BANF1,SESTD1,CARTPT,KLHL1,FOXA3,TAS2R13,DBR1,PRKCE,ZNF451,GNRH1,WDSUB1,TSPAN17,PRKRA,COX6B2,RNF133,TMEM170A,MT1E,ELK3,CRISP1,LRRC40,DPH3,CD81,RHOBTB3,HGS,POLDIP3,POLR2L,FSTL1,UBE2E2,TRAPPC13,PSD2,PEBP4,GH1,BAX,ATP1A3,NUDT2,NPM3,TMEM38B,TSPAN15,GSTM4,CRTC2,RPIA,VTA1,COX6C,PICALM,XAF1,PIK3AP1,FEM1C,COCH,ADORA3,APEX2,SF3B1,TAB1,AKR1B1,TMEM47,MAD2L1BP,LY96,AP1S2,ANKMY2,CNN3,CPT1B,ZBTB39,RBM27,CDH11,ERVV-1,PSMC3,JAKMIP2,SNRNP40,FAM83B,IVNS1ABP,PIK3CA,NDUFS2,PAIP2,TMEM185A,GTF2F1,DLST,GSTCD,TMED9,SYNPR,BCL6,SSX2IP,ZNF263,TPPP3,SGTA,USP6NL,MTDH,PET117,CA2,SNX10,MIS12,TMEM89,HSD17B10,CAND1,PRNP,GABRA1,ASPA,LYPD6,ELMO2,TRPC1,HS2ST1,GTPBP8,DR1,CBX3,ROCK2,KCND3,FUBP3,VPS72,KRIT1,TBCCD1,TRAF6,RPL18,GIN1,TKTL1,CCDC106,ETNK2,CLDND1,RPS10,SPRY1,IMPA2,FUNDC1,AP1M1,ECHDC1,TMEM196,TADA3,TRAM1,CCSER2,MTCH2,ITM2B,MDC1,TRAPPC6A,PSEN1,MAGEC2,OR13A1,LCORL,EDA2R,LMO2,FKBP1B,RBP2,TLCD1,AQP11,SSBP4,RASSF8,KCTD17,CLEC6A,DIRAS2,MREG,ACER3,ARHGAP12,EIF5B,PFKFB2,SRFBP1,FAM161A,PDE12,ANKRD6,YTHDF2,SLC12A2,RUNX1,GJC1,NAA16,TAPT1,TYMS,MED10,ZFAND6,SCML1,PDE7A,SUCLG2,DUSP3,ZNF581,VPS18,GHRL,ATP8A1,CIAO1,KIF3C,TTC9C,PELO,GMPS,THUMPD1,GORASP2,RXRG,SNAP25,CCR7,IGF1,DLGAP4,CMA1,GRIK1,RRAGB,SNRPE,GALNT2,IL18BP,RASL12,ANXA4,KCTD3,PIH1D1,RDH11,NKAP,LBX1,LRRC8A,SSPN,GNGT2,CNPY1,OR5M9,HAUS2,GALC,ELFN2,RP9,DMPK,ELFN1,MBD3,CDC23,MPG,BRAP,TANK,SYNGR3,WSB1,LYZ,OAZ1,SLC25A5,SLC35E4,FAM151B,ADCK1,CYBRD1,ZNF518B,MACROD1,RPE,SULT1B1,KLHL25,TMEM165,OR8B4,IRF7,PTP4A2,FAM3C,MFAP3L,SLU7,VEZT,CYTH4,IFT172,CPNE2,RAMP3,KLRC2,TOX4,CENPL,IER3,NUCKS1,TRIM26,FEM1B,UBE2G2,MRPL9,MECR,SGIP1,MRPS17,FXN,UPRT,SUPT3H,ITGB8,BTG2,VAV2,CCDC3,GNB3,HINFP,NUFIP2,CMC1,TMEM229B,TRIM44,LRP10,PAIP2B,NR1I3,FAM20B,PQBP1,GPRASP2,PPWD1,NRM,THAP8,WDR45,CRYBA1,MPV17L2,HSPB6,GNA11,SERTAD2,HSPA5,RNASEH2C,EIF1AX,HSPD1,LRRC28,TCEA2,PARD6A,TMEM115,NPC2,NUPR1,PIAS1,PNPLA4,CAP2,EXOC3,SAP18,DDR1,SPG21,TIA1,SLC22A6,ATG9A,ZNF622,S100A11,VPS54,SLC25A27,TGFB2,RBMS2,BOLL,MX1,GLOD4,PIGA,THOC3,BTG3,TMEM183A,DPEP3,IGFBP3,GADD45A,GRPR,RUSC2,CD9,OR1M1,ZNF428,PDE2A,CDIPT,TNFSF8,PYCR2,RAB6A,CTTNBP2,RGN,PLAC1,PSMD7,SCAND1,SIN3A,CDK7,CRY1,CD40,AIP,SLC6A2,TNFSF15,PMPCA,TLR8,ARFGEF1,NOG,TAB2,SRPK2,CCDC90B,RGP1,TRAF3IP3,PIWIL1,TMEM107,RPA2,RNASE9,GADD45G,PRSS8,LDB2,YPEL4,TMEM100,DCTPP1,OR4A47,PRCP,EID2B,CPXM1,THAP1,UNC79,CD34,FBXL4,GLCE,GK5,SLC25A24,SPINK9,SUPT5H,PDCL,RPL10,TRIP4,STAR,ST3GAL2,TAS2R7,CD209,FBXW4,P2RY4,IP6K1,PTGFR,IL2RB,ZDHHC16,OR4D5,TEX261,MSH6,RAP2A,PPP1R11,MDFI,POLR1D,GPR160,DTWD2,PSMD3,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,POLE3,KRTAP8-1,GP9,OR51E2,FAM133B,RNF10,CD200,TMEM168,USE1,ST8SIA4,TMEM220,NCK1,STRADB,LRP3,SIAH1,PLEKHF1,AHSA1,ZBTB6,KCTD16,SLC15A1,GPR78,HNRNPAB,TEX19,TRIM62,ZNF655,CDKN1B,CMBL,COX7B2,SCHIP1,MEA1,TAF9,SCG5,PHOSPHO2,MAT2A,NMRAL1,RFX5,TRAPPC2L,TMEM198,OR6C4,LRRN4CL,SSBP2,PDCD10,GDAP1L1,WTAP,RPL31,ZSWIM7,MGST3,TSPAN3,BAD,PRPS1,HAS3,OLA1,AKR1E2,CRHR1,NOC4L,UQCRC1,KCTD20,RASSF4,SERPINA3,CLK1,SKAP2,RSL24D1,TRAF1,BRS3,ZMAT3,NAA30,C9orf72,CDR2,PTGER2,NETO1,DDX39B,CGRRF1,LSM4,IRF9,HSD17B8,DOK6,SEMA3C,PSMB4,HERC3,CAMKV,ESYT1,F2,ARL5B,ANKH,YKT6,VPS26B,AANAT,EDC3,SAP30BP,HAPLN2,WNT2,GMDS,TRAPPC3,NRGN,CSRNP3,LDB1,MFSD3,SNN,SNRPA1,CEP70,ARL6IP5,ANKRD46,ABHD2,CTDSPL2,PSMG2,DTL,NDFIP1,KDM1A,CCDC22,TBCEL,UNC45A,FKBP2,PRSS35,RALB,NUDT1,TMEM87A,ISG20,GMNN,CYP26A1,RPLP1,SNX11,SERPINB9,TIMMDC1,IMP4,HELT,PDE6A,EMX2,SEC61G,CENPM,SSH3,HOXB8,GFM1,ADIPOR1,GAL3ST4,MET,FZD6,RETSAT,POPDC3,SLC7A11,RANBP1,CTLA4,RBM5,ATF3,MAP1LC3B,PDLIM3,PRSS37,IFRD1,DEFB1,ACSS2,RHOU,B3GALT4,DLG3,CEBPE,RPL22,BHLHA9,TMEM176B,RACGAP1,CORO1C,RBM3,RRP7A,CCDC126,STT3A,MAGEA4,PIK3CG,RPSA,NPBWR1,HYAL2,UBE2S,ERLIN2,ARHGAP15,RHOH,TMEM126A,SETD3,GPR75,ACP2,FOSL2,GNPAT,NDUFAF6,ACTL6A,STARD7,DIO2,WBP11,ZNF436,ZNF343,SYPL1,CHTOP,TBC1D1,GPR34,XBP1,RPF2,TIMM13,GABBR1,ERCC3,THG1L,PDLIM4,TACR1,CEP57L1,OSBPL8,CA14,DIS3L,CEACAM5,NAP1L3,DRD3,MTA3,EMILIN3,CHRM5,NACC2,SEMA7A,NAP1L5,APOC2,CYB5B,ZCRB1,MED4,BCKDK,TRMT5,OR9I1,HPCAL1,LIPT2,MRGPRX1,AQP3,RIMKLB,PSMG4,PRELID1,APMAP,ETFA,CD59,ECD,PRSS1,APEX1,PSMC5,GAB1,JMJD8,ITPRIPL2,AKT2,CHST10,KCNG3,SOX9,OR2D3,PNPO,COTL1,GPM6A,HS3ST3A1,TICAM1,TLR5,HIGD1C,RFC4,LCN1,DCAF16,CLRN2,SRD5A3,DNM2,OR4K13,TSPYL4,PLCXD3,C1QL2,REG1A,MMP20,GTF3C4,SMARCB1,HTR2A,ACTR1B,STAP1,STARD5,FMO1,ABCC2,SUGP1,ALG5,SCN2B,ANKRD10,TEF,TMEM231,PCP2,TCTA,SOD2,ADD2,KLF12,MLN,IAH1,WDR12,GLO1,RAB1A,PDCD1LG2,NEU1,VSTM4,PIGK,PELI1,CNOT8,MAP1B,ZDHHC17,FBXO31,VSTM2L,CRYZ,FOXC2,PITPNA,RAB32,CRYBA4,BLVRA,FAM193B,APOBEC3B,MLH3,PCBP4,TULP3,HS3ST1,BMPR1B,OR4M1,SPDYE4,ADH1B,SRM,MED27,RANBP10,BARX2,PSMD1,MPP1,IFI16,PTPRZ1,SART3,MYLIP,FAM174A,SUPT4H1,VPS39,CFTR,ATG3,INA,CLP1,CLPX,OR5AN1,VWF,ATP6V1D,GPR37,ESD,TMEM39A,ART5,PSMB10,CDK17,DIRAS3,TP53TG5,ATG16L1,HDAC11,SIGLEC5,TTLL10,CHCHD2,SKP1,PCYT1B,CSF2,KRT8,PRELP,GJB1,HNRNPH3,AGGF1,LCP1,IZUMO2,TPST1,ZNF200,RBM41,COPE,RWDD1,SLC25A3,PABPC5,HCFC2,DCTN3,LSM5,IRF2BPL,PRKCB,RGL1,SUV39H1,RPL4,SEC14L5,HBP1,SPAG11B,CKS1B,DYNLRB2,CYP4F22,STK38L,MVD,PIGC,ARFGAP1,SHC3,CDC26,PREP,SLITRK1,DDIT3,SRP72,EDEM2,FIS1,PDF,CACNB2,MB21D2,LCN15,PGAP3,TCEA1,HM13,BCAS4,SLC39A10,VCPIP1,WBP1L,OAZ3,JUNB,ALCAM,SNRPD1,CCL24,LIPA,RNF182,SMAD9,TIMM17A,RELL1,UFSP1,PTPN5,MARCKSL1,IFNAR1,SDR16C5,SLA2,PYCR1,THOC6,TNPO2,HINT1,RPAP3,RAB9A,RXFP2,CCL11,OPRL1,LYPLAL1,HSDL2,DYNLL1,PLP2,ABCF1,DUS4L,SMG5,NUP62,RNF139,ADRB3,FMOD,TBC1D16,CA12,SLC7A1,SPATA4,CMTM7,LEMD3,CSRP1,CCND3,RAB11B,ARL6,STX5,FHIT,MAP3K3,KRTAP4-1,TECR,MRPL16,RNF7,EZH1,ARGLU1,PNRC1,SLC41A1,LAMTOR2,MFAP1,MXD1,MED29,UBE2I,UCP2,TMEM106B,MID1IP1,SPCS1,TDP1,GLIPR2,PLEKHF2,SNRNP70,SERINC1,SLC6A7,MAGEB1,DICER1,SLITRK5,SAP30,DDIT4L,RNASE4,HBM,POU5F1,MSN,FGF16,ZNF362,RPL19,IL21,LRFN3,TNIK,S100B,PDE6D,PDZK1IP1,OR5K1,OR4B1,UBE3A,SH3BP4,LEP,PITHD1,ZC4H2,CETN2,TADA1,ZC3H14,EFNA5,ASPM,IFNA13,CACNG3,RIT2,DCTN4,SEC22A,MAP2K3,DOK5,FIG4,LSM12,CXXC1,RPL7A,FAM20C,SPHK2,RCHY1,MRPL12,FGR,B3GALT2,PPT1,ZDHHC24,BTBD10,PDCD5,PRDX3,EMILIN1,ZBTB26,LRRC14,TUBA1B,CKB,THAP6,HMGB1,PHF7,MRPS26,GNG11,EIF2B2,ZMYM6,ARF1,ZHX1,KCNIP2,SERTAD1,ERRFI1,FA2H,HNMT,NPB,DPAGT1,CTSA,PHTF2,ZCCHC7,PPIL3,GPR83,LPCAT3,KIAA1958,ZNF345,EID2,LYRM2,FBLN5,FOXD3,MAEA,CXCL10,SLC37A4,CDH7,ASCC1,SVIP,SMUG1,RPS28,UBXN2B,TPD52L1,ZNF770,SEC61A1,TTR,METTL18,RSBN1L,GAD2,BGLAP,CDC42SE1,COX7B,RHOG,NOL12,FAM83A,ASB11,RGS1 |
| 2.791e-02 | -3.58 | multivesicular body organization | biological process | GO:0036257 | 32 | 15 | 18204 | 5365 |
CHMP5,VPS28,CHMP1B,TSG101,UBAP1,CHMP2A,VTA1,CHMP1A,RAB27A,RAB11A,VPS4A,HGS,CHMP2B,CHMP4C,VPS4B |
| 2.791e-02 | -3.58 | adult walking behavior | biological process | GO:0007628 | 32 | 15 | 18204 | 5365 |
FKRP,CEND1,CACNB4,DRD1,FXN,HEXA,ABHD12,GLRB,KLHL1,GLRA1,EPHA4,KCNJ10,ZMPSTE24,CLN8,HTRA2 |
| 2.791e-02 | -3.58 | RHESUSRHD | prints domains | PR00342 | 5 | 4 | 5227 | 1528 |
RHBG,RHCE,RHCG,RHAG |
| 2.791e-02 | -3.58 | MUSCARINICR | prints domains | PR00243 | 5 | 4 | 5227 | 1528 |
CHRM1,CHRM4,CHRM3,CHRM5 |
| 2.791e-02 | -3.58 | GSTRNSFRASEM | prints domains | PR01267 | 5 | 4 | 5227 | 1528 |
GSTM3,GSTM4,GSTM2,GSTM5 |
| 2.795e-02 | -3.58 | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 30 | 14 | 16828 | 4835 |
SMAD4,KRAS,PIK3CA,PTEN,DICER1,RB1,KIT,MET,CTNNB1,BRCA1,TP53,JAK2,NF2,AKT1 |
| 2.795e-02 | -3.58 | Prot_ATP_ID_OB_2nd | interpro domains | IPR032501 | 5 | 4 | 18521 | 5414 |
PSMC1,PSMC3,PSMC4,PSMC5 |
| 2.795e-02 | -3.58 | TLV/ENV_coat_polyprotein | interpro domains | IPR018154 | 5 | 4 | 18521 | 5414 |
ERVV-2,ERVV-1,ERV3-1,ERVFRD-1 |
| 2.795e-02 | -3.58 | GST_mu | interpro domains | IPR003081 | 5 | 4 | 18521 | 5414 |
GSTM5,GSTM2,GSTM3,GSTM4 |
| 2.795e-02 | -3.58 | LRRC8_Pannexin-like | interpro domains | IPR021040 | 5 | 4 | 18521 | 5414 |
LRRC8A,LRRC8C,LRRC8B,LRRC8D |
| 2.795e-02 | -3.58 | Cys_alpha_HP_mot_SF | interpro domains | IPR009069 | 5 | 4 | 18521 | 5414 |
COX19,COX17,CHCHD1,CMC4 |
| 2.795e-02 | -3.58 | NH4_transpt_AmtB-like_dom | interpro domains | IPR024041 | 5 | 4 | 18521 | 5414 |
RHCE,RHBG,RHAG,RHCG |
| 2.795e-02 | -3.58 | Porin_Euk/Tom40 | interpro domains | IPR027246 | 5 | 4 | 18521 | 5414 |
TOMM40L,TOMM40,VDAC1,VDAC2 |
| 2.795e-02 | -3.58 | Musac_Ach_rcpt | interpro domains | IPR000995 | 5 | 4 | 18521 | 5414 |
CHRM5,CHRM3,CHRM4,CHRM1 |
| 2.795e-02 | -3.58 | Selenoprotein_Rdx-typ | interpro domains | IPR011893 | 5 | 4 | 18521 | 5414 |
SELENOV,SELENOT,MIEN1,SELENOW |
| 2.795e-02 | -3.58 | Trimer_LpxA-like_sf | interpro domains | IPR011004 | 5 | 4 | 18521 | 5414 |
EIF2B5,EIF2B3,FPGT,DCTN6 |
| 2.795e-02 | -3.58 | Histidine_triad_CS | interpro domains | IPR019808 | 5 | 4 | 18521 | 5414 |
HINT1,FHIT,APTX,HINT2 |
| 2.795e-02 | -3.58 | Torsin | interpro domains | IPR010448 | 5 | 4 | 18521 | 5414 |
TOR4A,TOR3A,TOR1B,TOR2A |
| 2.795e-02 | -3.58 | IsoPropMal-DH-like_dom | interpro domains | IPR024084 | 5 | 4 | 18521 | 5414 |
IDH3A,IDH1,IDH3B,IDH2 |
| 2.795e-02 | -3.58 | SOX_fam | interpro domains | IPR022097 | 5 | 4 | 18521 | 5414 |
SOX3,SOX14,SOX21,SOX2 |
| 2.795e-02 | -3.58 | IsoCit/isopropylmalate_DH_CS | interpro domains | IPR019818 | 5 | 4 | 18521 | 5414 |
IDH2,IDH1,IDH3A,IDH3B |
| 2.795e-02 | -3.58 | RhesusRHD | interpro domains | IPR002229 | 5 | 4 | 18521 | 5414 |
RHCE,RHAG,RHCG,RHBG |
| 2.795e-02 | -3.58 | Cyt_B5_heme-BS | interpro domains | IPR018506 | 5 | 4 | 18521 | 5414 |
FA2H,CYB5R4,CYB5B,CYB5A |
| 2.795e-02 | -3.58 | Porin_dom_sf | interpro domains | IPR023614 | 5 | 4 | 18521 | 5414 |
VDAC2,VDAC1,TOMM40,TOMM40L |
| 2.795e-02 | -3.58 | TRAPP_component | interpro domains | IPR007194 | 5 | 4 | 18521 | 5414 |
TRAPPC3,TRAPPC3L,TRAPPC6A,TRAPPC6B |
| 2.795e-02 | -3.58 | FMR1 (fragile X messenger ribonucleoprotein 1) | protein interactions | 2332 | 275 | 92 | 19454 | 5460 |
PSPC1,STUB1,CCNF,EIF4A3,GSK3A,RPS20,UBE2I,USP14,RC3H2,IGF2BP1,MAPRE1,UBE2H,CASC3,SIRT7,LSM12,RNF113A,MTDH,FBXW7,EIF4E,ATG16L1,AGO1,WTAP,HECTD1,SYNCRIP,FZR1,RPS16,CGAS,THOC1,RBM42,DKC1,ZBTB2,CWC15,MOV10,DPP4,GRSF1,SNRNP70,SMG8,SSX2IP,MAP1B,TCOF1,EFHC1,DHX9,PHF1,TBK1,YTHDF2,CASK,NUPR1,DLST,KBTBD2,ERH,PRRC2A,RPL10,MYC,BTF3,BAG3,CHTOP,FXR2,CYFIP2,UFL1,YTHDF1,STAU1,RNF41,G3BP2,SYK,WDR77,LARP4B,NUFIP2,ZBTB42,FUBP3,HOMER3,CCAR2,PSMD3,IFI16,WWP2,DDRGK1,CTNNB1,NCK1,MAGOH,TRIP4,BCL7B,LSM14A,ZC3H7A,PICK1,G3BP1,KRAS,DCTPP1,RAF1,TOP3B,E2F4,GLE1,EZH2,PDHA1 |
| 2.804e-02 | -3.57 | DAB2 (DAB adaptor protein 2) | protein interactions | 1601 | 124 | 45 | 19454 | 5460 |
PRKCB,RHOU,DVL2,STX7,PPP1CB,CFTR,CDK1,PICALM,AP2M1,RTRAF,GSK3A,SMAP2,ATXN1L,SRC,APEX1,ACTB,NONO,CDC16,AKT3,CSK,PYCR1,AP2A1,SMAD2,MAPRE1,LAMTOR1,RHOB,MYO6,TGFBR2,ISG15,ITGB5,SGIP1,ACTR2,CAPZA2,RAC2,LDLR,SMAD3,STX6,HNRNPL,SUMO2,FCHO2,RHOH,XPO1,PRDX1,ATG9A,FGR |
| 2.804e-02 | -3.57 | HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) | protein interactions | 3156 | 124 | 45 | 19454 | 5460 |
ARHGAP1,SEC62,CTBP1,EP300,CYP2C18,SYVN1,VIPR1,LPAR1,TMUB1,RNF148,GPR17,CHRAC1,RIC3,ATP1B3,IGF2BP1,MARCHF3,SEC61B,ACVR1C,INSIG2,ERLIN2,FAF2,UBIAD1,CD209,RPN1,STARD13,TRAPPC13,RAB1A,AKT2,IGF1R,SLC39A7,TMEM268,LPAR2,SLC39A3,SRPRB,ARL5B,KRAS,CCR6,RNF139,TMEM30A,TST,LDLR,SPINT2,MARCHF4,DCUN1D1,RAB1B |
| 2.804e-02 | -3.57 | GLI4 (GLI family zinc finger 4) | protein interactions | 2738 | 124 | 45 | 19454 | 5460 |
HP1BP3,MRPS9,KRR1,DKC1,NOP9,RPS10,RPS16,MRPL50,MRPL9,NGDN,MRPS35,MRPS26,RPS2,MRPS18B,RPL3,MRPS11,MRPL52,SRSF12,RPL17,MRPS33,TRIM63,ZNF397,RPL15,TRIM27,MRPS28,ZNF22,ZNF189,RPF1,ZSCAN25,NOA1,ZCRB1,NGRN,MRPS7,BRIX1,RNF41,AATF,RPS15,MRPL57,STAU1,RETN,NOTCH2,ZNF574,RPL26L1,ZNF770,MRPS34 |
| 2.805e-02 | -3.57 | THAP7 (THAP domain containing 7) | protein interactions | 80764 | 96 | 36 | 19454 | 5460 |
SMARCD3,NLE1,FBXO11,PICK1,FHL3,HDAC3,H3C1,TRIM26,RPS27A,LDOC1,ZDHHC17,HINFP,ASPM,MAP1LC3B,TRAF2,GABARAPL1,PNMA2,RBM34,TFIP11,RPL26L1,LURAP1,RPL32,MAGOHB,RPL13A,RPL7,TRAF1,MDFI,RPL26,THAP7,FBXO7,NTAQ1,EXOC1,TPM3,CCDC85B,DESI2,H1-1 |
| 2.805e-02 | -3.57 | PRPF18 (pre-mRNA processing factor 18) | protein interactions | 8559 | 96 | 36 | 19454 | 5460 |
GAS8,CEP70,PFDN5,MDFI,SPRED1,TOPBP1,TSNAX,BICD2,TRIM23,YWHAZ,GCC1,CSRNP1,AP2M1,TRIM27,PDE9A,GTF2B,PNMA1,PRPF18,SNRNP40,TRIM54,FZR1,TRAF2,DDX39A,AGTRAP,TFIP11,CDR2,ZNF526,SCHIP1,PPIH,PICK1,RINT1,PML,RHOU,STX11,LDOC1,LSM4 |
| 2.805e-02 | -3.57 | RNF168 (ring finger protein 168) | protein interactions | 165918 | 96 | 36 | 19454 | 5460 |
UBE2E2,MARCHF5,TRIM8,TNFAIP3,SMARCA5,USP14,BRCA1,H2AC4,UBE2D1,BCL10,CCDC174,DDX1,COP1,UBE2G2,UBE2N,H2AZ1,MACROH2A1,SUMO2,SUMO3,STAT1,DHX15,UBE2L3,UBB,SUMO1,H2AX,RPRD1B,RNF126,WBP2,DHX9,SQSTM1,EWSR1,H2AC13,KDM1A,UBE2D3,DGCR8,RNF11 |
| 2.805e-02 | -3.57 | SPTY2D1 (SPT2 chromatin protein domain containing 1) | protein interactions | 144108 | 96 | 36 | 19454 | 5460 |
RBM34,RPL18,SART3,MACROH2A2,RPLP0,MAGEB10,RPS14,RAF1,RPL15,ASF1A,ZNF692,DGCR8,KRAS,SSRP1,RPL17,RPL28,RPS13,COIL,NLE1,RPL31,SNIP1,HAPSTR1,ZBTB38,PLEKHO1,RPL7A,MYC,SNRNP40,RPL13A,TOP1,SURF6,ESR2,PPP1R10,ZNF330,ARL4D,PRKRA,FGFBP1 |
| 2.808e-02 | -3.57 | PITHD1 (PITH domain containing 1) | protein interactions | 57095 | 42 | 18 | 19454 | 5460 |
FNTB,TSEN34,COPS5,FRA10AC1,DHX38,YWHAB,UBE2H,CDC73,CRMP1,STX17,RPRD1A,CCNF,CETN2,EGLN3,CLDND1,PRNP,FXR2,PSMD4 |
| 2.808e-02 | -3.57 | CLDN5 (claudin 5) | protein interactions | 7122 | 42 | 18 | 19454 | 5460 |
TMEM190,SFTPC,TMEM182,SLC35B4,CNPY3,CCDC167,PLP2,PMP22,EHHADH,VAMP5,EFNA5,CLRN2,TECR,TF,CXCL9,ERG28,CLDN3,RPRM |
| 2.808e-02 | -3.57 | PEX12 (peroxisomal biogenesis factor 12) | protein interactions | 5193 | 42 | 18 | 19454 | 5460 |
GJB2,SEC22A,NRM,SRGN,FXYD6,TMEM11,SMCO4,SEC61G,PEX3,BTN2A2,STX8,CYBC1,FA2H,AKAP1,ADIPOQ,DNAJC30,APEX1,FKBP8 |
| 2.808e-02 | -3.57 | C16orf87 (chromosome 16 open reading frame 87) | protein interactions | 388272 | 42 | 18 | 19454 | 5460 |
ANAPC16,ANAPC2,DR1,H2AZ1,RIGI,FZR1,H2AX,NEK2,ANAPC13,AR,CDC16,MOV10,CDC26,ZBTB38,CDC23,ANAPC4,H2BC1,H2AC4 |
| 2.808e-02 | -3.57 | FGF1 (fibroblast growth factor 1) | protein interactions | 2246 | 42 | 18 | 19454 | 5460 |
FGFR1,GTF2IRD1,SDC2,NRP1,RPS2,CSK,CSNK2A1,GPC4,FGF1,GPC1,RPL7L1,KDM1A,NEDD8,HMG20A,SDC4,KLHL7,CSNK2B,FGFBP1 |
| 2.808e-02 | -3.57 | PRCP (prolylcarboxypeptidase) | protein interactions | 5547 | 42 | 18 | 19454 | 5460 |
ABCE1,HNRNPH2,NCDN,NUCKS1,PDHB,PPP1R2,LDHA,TOMM40,DDX39A,LDHB,PGAM1,VDR,PNPO,POU5F1,STK24,PDHA1,ISOC1,TUBB4B |
| 2.808e-02 | -3.57 | MEST (mesoderm specific transcript) | protein interactions | 4232 | 42 | 18 | 19454 | 5460 |
SMYD3,CEP70,RND2,SOX2,FBXO7,TOMM40,CDC42,ING5,CIDEB,RHOBTB1,HGS,GAD2,BLOC1S2,FEZ1,TMEM106B,VDAC2,VDAC1,RHOH |
| 2.814e-02 | -3.57 | lipid homeostasis | biological process | GO:0055088 | 179 | 65 | 18204 | 5365 |
MYLIP,MIR148A,SESN2,RTN4,TLCD2,LAMTOR1,XBP1,TSPO,ORMDL1,MIR208A,FABP4,FUNDC2,PPARG,SLC25A27,TLCD3B,CYP7A1,TMEM97,LIPA,ACOX1,PCSK9,APOC2,SAR1B,PNPLA4,NR1H2,APOC4,AKR1C1,CAV1,CLN8,HPS6,ADCK1,ACACA,CAV3,MIR33B,NUS1,PNPLA8,ERRFI1,LDLR,MIR132,SLC25A46,ADORA1,IL18,ORMDL3,MIR182,MINAR2,TLCD4,MTCH2,ABHD5,MIR590,TLCD1,FBXW7,NPC1L1,MIR144,MIR185,ABHD4,FITM2,PLSCR3,EHD1,CYP39A1,NPC2,MIR34A,SURF4,GPIHBP1,MIR379,GPAM,COMMD9 |
| 2.819e-02 | -3.57 | PIPSL (PIP5K1A and PSMD4 like (pseudogene)) | protein interactions | 266971 | 249 | 84 | 19454 | 5460 |
CETN2,EGLN3,PNPLA8,TSPYL4,PRELID1,CETN3,RB1CC1,NOS1AP,TDRD7,PSMD10,TLR10,SUV39H1,DDRGK1,SETD5,CMSS1,SEPHS1,PCGF6,RAD21,PDRG1,PSMD12,MEPCE,IMP4,CDK20,VRK1,TSSC4,COA1,ZNF592,SKA1,UBE3A,RABGGTB,TOP2B,LTA,NDUFB5,MRPL51,CHAMP1,SKA3,DMAP1,MRPL36,RPL15,GTPBP8,ASPM,DCAKD,CSNK1E,RAF1,CEP97,VIRMA,ESR2,RPF1,ADRM1,RPL7L1,B4GALT4,ZNF622,SENP5,FAM43A,LIG3,ZNHIT6,MTG1,DCAF4,PSKH1,RBBP8,MCM3,TMEM183A,ALKBH2,HS3ST3A1,MRM2,SMARCA5,MRPL20,FTL,PSMC1,ARHGEF39,TSR3,NF2,MAVS,NUBP2,AMACR,PRIM2,MACROH2A2,UTP15,SKA2,ELP3,FTH1,ATAT1,PIP5K1A,ARHGAP1 |
| 2.821e-02 | -3.57 | RCC2 (regulator of chromosome condensation 2) | protein interactions | 55920 | 194 | 67 | 19454 | 5460 |
GRM2,RPA2,CTBP1,PIH1D1,EIF4B,CDC42,STAU1,UFL1,NF2,PDHB,MARS1,SIRT7,RPA3,BAP1,EP300,RNF113A,DCAF4,CCT2,UBE2H,COP1,ZBTB38,PSMA4,TNFAIP3,MYC,RACGAP1,AR,SNRNP40,NDN,ESR2,PSMB6,CCNF,MSN,PTEN,SNRPD1,RAB4A,NUPR1,TP53,B3GNT2,EEF1A1,NCSTN,PAK1IP1,H3C1,TNF,G3BP1,EIF2D,PSMD12,PABPC1,PSME1,FAF1,SNRNP70,TSNAX,WWP2,EMC4,IFI16,DDRGK1,HDAC6,COPS5,CSNK2A1,BUD31,SNRPD3,FZR1,DHX15,CCT7,MBD5,PSMB5,CORO1C,PREP |
| 2.825e-02 | -3.57 | UBAP2 (ubiquitin associated protein 2) | protein interactions | 55833 | 162 | 57 | 19454 | 5460 |
YTHDF2,TOP3B,RAF1,KBTBD4,HGS,PABPC1,LSM14A,GLUL,SCYL2,BAG2,HAPSTR1,EFHC1,ZC3H7A,VDAC1,S100A10,G3BP1,TFG,WWP2,ISX,CNOT2,PLAC8,SHC3,YWHAH,CPEB1,YWHAG,SPMIP9,THY1,FZR1,EGLN3,ZC3H14,RBFOX2,LARP4B,RPA2,WRAP53,TRAPPC6A,DYRK2,NUFIP2,FAM168B,RPA3,ATPAF2,NUP50,STAU1,YTHDF1,FXR2,G3BP2,STX7,CUL3,MYC,MGAT5B,GORASP2,TOMM40,BRCA1,UBE2H,SMAP2,CCNF,RPS20,PRRC2A |
| 2.825e-02 | -3.57 | DBNL (drebrin like) | protein interactions | 28988 | 162 | 57 | 19454 | 5460 |
GANAB,CCNF,EIF2AK2,HOMER1,DYRK1A,APEX1,ESR2,ACTB,CFL1,BAG3,MCM4,MYC,OSGEP,BICD2,HSPA8,DDX5,ARPC2,DR1,RBM23,HIRA,BAP1,RPA3,CMAS,GON7,STAU1,CNPY3,CNP,CFTR,ATG16L1,SYK,PAQR3,DCTN4,P3H1,RPA2,HSP90B1,TES,EGLN3,CYP4F8,RPL35A,YWHAG,YWHAH,RB1CC1,CBL,AGPAT1,ERO1A,BAG2,UBE3A,SAR1B,G3BP1,TOLLIP,GTF2E2,PHF23,CDK4,CCR1,PPME1,EZH2,CAPZA2 |
| 2.826e-02 | -3.57 | Glucose metabolism | REACTOME pathways | R-HSA-70326 | 81 | 34 | 10285 | 3229 |
PGAM1,ENO2,SLC25A1,GYS1,PFKFB2,ENO1,PYGM,PHKA1,PCK2,MDH1,GNPDA1,SLC25A12,UGP2,PYGB,PPP2CB,FBP1,BPGM,FBP2,PHKB,GNPDA2,PPP1R3C,PGM1,PC,PHKG1,UBA52,PRKACB,RPS27A,UBB,GBE1,SLC25A11,PPP2R1A,GAPDH,SLC25A10,PGK1 |
| 2.828e-02 | -3.57 | positive regulation of gene expression via chromosomal CpG island demethylation | biological process | GO:0044029 | 14 | 8 | 18204 | 5365 |
APOBEC3A,APOBEC3F,ZMPSTE24,NIBAN2,APOBEC3C,EGR1,OGG1,APEX1 |
| 2.828e-02 | -3.57 | negative regulation of macrophage migration | biological process | GO:1905522 | 14 | 8 | 18204 | 5365 |
EMILIN1,MMP28,CD200R1,MIF,MIR24-1,DDT,CD200,STAP1 |
| 2.828e-02 | -3.57 | regulation of protein localization to chromosome, telomeric region | biological process | GO:1904814 | 14 | 8 | 18204 | 5365 |
CCT5,TCP1,CCT2,DKC1,WRAP53,MACROH2A1,CCT8,CCT7 |
| 2.828e-02 | -3.57 | regulation of keratinocyte migration | biological process | GO:0051547 | 14 | 8 | 18204 | 5365 |
HBEGF,MMP9,MAPRE2,FGF7,ARF6,FGF10,IQSEC1,PTEN |
| 2.828e-02 | -3.57 | inflammatory response to wounding | biological process | GO:0090594 | 14 | 8 | 18204 | 5365 |
CCR2,TNF,IL6,TLR4,WDR83,TIMP1,IL1A,TLR3 |
| 2.828e-02 | -3.57 | deoxyribonucleotide biosynthetic process | biological process | GO:0009263 | 14 | 8 | 18204 | 5365 |
GUK1,RRM1,ADK,DTYMK,TYMS,DCK,AK5,SHMT1 |
| 2.828e-02 | -3.57 | cellular response to ethanol | biological process | GO:0071361 | 14 | 8 | 18204 | 5365 |
TP53INP1,UGT1A1,PRKCE,GLRA1,SOD2,GLRA2,KCNMB1,SLC23A2 |
| 2.828e-02 | -3.57 | 2'-deoxyribonucleotide biosynthetic process | biological process | GO:0009265 | 14 | 8 | 18204 | 5365 |
ADK,DCK,TYMS,DTYMK,GUK1,RRM1,AK5,SHMT1 |
| 2.828e-02 | -3.57 | Golgi localization | biological process | GO:0051645 | 14 | 8 | 18204 | 5365 |
YWHAZ,ARHGAP21,TBCCD1,STK11,CDC42,ARCN1,PDCD10,NHERF1 |
| 2.828e-02 | -3.57 | deoxyribose phosphate biosynthetic process | biological process | GO:0046385 | 14 | 8 | 18204 | 5365 |
AK5,SHMT1,ADK,TYMS,DTYMK,DCK,GUK1,RRM1 |
| 2.828e-02 | -3.57 | non-lytic viral release | biological process | GO:0046753 | 14 | 8 | 18204 | 5365 |
CHMP5,CHMP1A,CHMP1B,VPS4A,CHMP2B,CHMP4C,VPS4B,CHMP2A |
| 2.828e-02 | -3.57 | positive regulation of striated muscle contraction | biological process | GO:0045989 | 14 | 8 | 18204 | 5365 |
CHGA,HSP90AA1,MIR1-1,ATP1A1,UCN,RGS2,GSTO1,ADRA1A |
| 2.828e-02 | -3.57 | layer formation in cerebral cortex | biological process | GO:0021819 | 14 | 8 | 18204 | 5365 |
COL3A1,CTNNB1,PAFAH1B1,NR2E1,ADGRG1,CDK5,BMERB1,CDK5R1 |
| 2.829e-02 | -3.57 | regulation of lymphocyte apoptotic process | biological process | GO:0070228 | 57 | 24 | 18204 | 5365 |
CCL5,LGALS3,FOXP1,IL10,TP53,PRELID1,IDO1,SLC39A10,PDCD1,RAG1,BAX,ARG2,GPAM,ST3GAL1,PTCRA,MIF,CD3G,ORMDL3,PRKCQ,BCL6,BCL10,CD274,IL2,TSC22D3 |
| 2.829e-02 | -3.57 | nucleoside metabolic process | biological process | GO:0009116 | 57 | 24 | 18204 | 5365 |
APOBEC3C,DTYMK,NUDT1,APOBEC3H,APOBEC3F,GNMT,NT5C3A,QNG1,MTAP,APOBEC3A,APOBEC3D,PNP,APOBEC3G,ENPP4,NME4,OARD1,ADK,UCKL1,APOBEC3B,DNPH1,DCTD,MACROD1,ERH,NT5C2 |
| 2.829e-02 | -3.57 | osteoclast differentiation | biological process | GO:0030316 | 57 | 24 | 18204 | 5365 |
FOXP1,PAFAH1B1,TYROBP,TNF,FOS,GLO1,SNX10,TOB2,MITF,FOSL2,CTNNB1,CREB1,SFRP1,TF,IREB2,TFRC,PIK3R1,JUNB,EPHA2,TRAF6,TCTA,FAM20C,OSTM1,CD81 |
| 2.834e-02 | -3.56 | positive regulation of cell development | biological process | GO:0010720 | 458 | 154 | 18204 | 5365 |
DAG1,FOXP3,PNP,IL18,CRABP2,CD83,PLXNC1,SASH3,NKAP,ACTL6A,VEGFC,KLHL25,SMARCE1,OPRM1,HAX1,BTN2A2,IL6ST,MMP14,IL12B,IFNG,EPHA4,TIAM1,PAFAH1B1,ACTL6B,MIR142,CD86,ASPM,HAPLN2,IL6,CLEC7A,CREB1,ID4,IL4,NPTN,AMIGO1,ZBTB16,GPRASP3,RUNX1,SOCS5,F11R,SMURF1,TLR9,NR2E1,SMARCD3,TSPO,TNFRSF1B,EGR2,LILRB4,CTNNBIP1,CD4,MIR21,PTN,NIBAN2,NTRK2,ANAPC2,FZD4,CD46,UFL1,WNT10B,SLITRK1,MECP2,SMARCB1,IL34,MYRF,TYROBP,PAX6,IL15,LGALS3,EFNA5,IL7,CBFB,CD80,VEGFA,PTPRZ1,SEMA7A,IL23A,BMPR2,KLF10,IL1B,BCL6,CXCL12,MME,PPP3CA,SYK,HMGB1,DUSP10,STK11,AGER,CXCR4,TESC,HDAC6,PRMT5,SEMA5A,TBC1D24,IL10,ASPA,CX3CL1,ADIPOQ,TNF,VSIR,NOTCH2,KRAS,EP300,ACTB,TOX,IL2RG,MAP1B,CX3CR1,MIR145,WNT2,CTNNB1,TRIM32,ADD1,TESPA1,NKX6-2,MIR222,RHEB,KIT,FZD3,TLR2,NLRP3,FXR2,TRAF6,PRKCA,NEFL,XBP1,RHOH,TRIB1,XRCC5,RND2,DICER1,MIR221,CCL19,EEIG1,IL2,TGFBR2,NRP1,KDM1A,FOS,HCLS1,DISC1,IL5,IL2RA,ADNP,RB1,ZNF365,BAD,MAP2K1,CCR1,PPP1CC,RAG1,IL15RA,LTA,L1CAM |
| 2.838e-02 | -3.56 | vasopressin receptor activity | molecular function | GO:0005000 | 7 | 5 | 18094 | 5411 |
AVPR1B,INPP5K,NPSR1,OXTR,NLRP6 |
| 2.838e-02 | -3.56 | RNA polymerase II CTD heptapeptide repeat phosphatase activity | molecular function | GO:0008420 | 7 | 5 | 18094 | 5411 |
RPAP2,CTDSPL2,CTDSP2,CTDSP1,SSU72 |
| 2.838e-02 | -3.56 | CCR5 chemokine receptor binding | molecular function | GO:0031730 | 7 | 5 | 18094 | 5411 |
CCL3,JAK1,CCL5,STAT1,CNIH4 |
| 2.838e-02 | -3.56 | thioredoxin-disulfide reductase (NADPH) activity | molecular function | GO:0004791 | 7 | 5 | 18094 | 5411 |
TXNRD1,TXNRD2,TXNRD3,SELENOT,TXN |
| 2.838e-02 | -3.56 | guanylyltransferase activity | molecular function | GO:0070568 | 7 | 5 | 18094 | 5411 |
FPGT,GMPPB,THG1L,TENT4A,GDPGP1 |
| 2.838e-02 | -3.56 | fatty acid elongase activity | molecular function | GO:0009922 | 7 | 5 | 18094 | 5411 |
ELOVL4,ELOVL3,ELOVL6,ELOVL1,ELOVL7 |
| 2.838e-02 | -3.56 | NEDD8 transferase activity | molecular function | GO:0019788 | 7 | 5 | 18094 | 5411 |
RNF7,UBE2M,MDM2,UBA3,UBE2F |
| 2.838e-02 | -3.56 | G protein-coupled opioid receptor activity | molecular function | GO:0004985 | 7 | 5 | 18094 | 5411 |
OPRM1,OPRK1,SIGMAR1,OPRL1,NPBWR1 |
| 2.838e-02 | -3.56 | G protein-coupled acetylcholine receptor activity | molecular function | GO:0016907 | 7 | 5 | 18094 | 5411 |
CHRM1,CHRM4,CHRM3,CHRM5,HRH3 |
| 2.838e-02 | -3.56 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | molecular function | GO:0034485 | 7 | 5 | 18094 | 5411 |
INPP5E,INPPL1,FIG4,OCRL,INPP5K |
| 2.839e-02 | -3.56 | NF-kappaB binding | molecular function | GO:0051059 | 29 | 14 | 18094 | 5411 |
CPNE1,BCL10,FOXP3,COMMD6,HDAC3,BRMS1,EP300,FAF1,NOTCH2,CDK5RAP3,ANXA4,MTDH,PSMA6,NFKBIA |
| 2.839e-02 | -3.56 | amino acid:monoatomic cation symporter activity | molecular function | GO:0005416 | 29 | 14 | 18094 | 5411 |
SLC6A11,SLC32A1,SLC6A12,SLC6A1,SLC38A2,SLC38A1,SLC38A3,SLC38A7,SLC1A2,SLC6A8,SLC1A1,SLC6A6,SLC6A7,SLC1A3 |
| 2.840e-02 | -3.56 | Ammonium_transp | pfam domains | PF00909 | 5 | 4 | 17795 | 5224 |
RHCE,RHAG,RHBG,RHCG |
| 2.840e-02 | -3.56 | GST_C_3 | pfam domains | PF14497 | 5 | 4 | 17795 | 5224 |
GSTP1,HPGDS,GSTO1,GSTA4 |
| 2.840e-02 | -3.56 | Methyltransf_23 | pfam domains | PF13489 | 5 | 4 | 17795 | 5224 |
HENMT1,METTL18,HNMT,METTL6 |
| 2.840e-02 | -3.56 | Porin_3 | pfam domains | PF01459 | 5 | 4 | 17795 | 5224 |
TOMM40,VDAC2,VDAC1,TOMM40L |
| 2.840e-02 | -3.56 | TRAPP | pfam domains | PF04051 | 5 | 4 | 17795 | 5224 |
TRAPPC6B,TRAPPC3,TRAPPC3L,TRAPPC6A |
| 2.840e-02 | -3.56 | Prot_ATP_ID_OB_C | pfam domains | PF16450 | 5 | 4 | 17795 | 5224 |
PSMC4,PSMC5,PSMC1,PSMC3 |
| 2.840e-02 | -3.56 | Pannexin_like | pfam domains | PF12534 | 5 | 4 | 17795 | 5224 |
LRRC8B,LRRC8A,LRRC8D,LRRC8C |
| 2.840e-02 | -3.56 | SOXp | pfam domains | PF12336 | 5 | 4 | 17795 | 5224 |
SOX21,SOX14,SOX3,SOX2 |
| 2.840e-02 | -3.56 | Rdx | pfam domains | PF10262 | 5 | 4 | 17795 | 5224 |
SELENOV,SELENOW,MIEN1,SELENOT |
| 2.840e-02 | -3.56 | Torsin | pfam domains | PF06309 | 5 | 4 | 17795 | 5224 |
TOR2A,TOR1B,TOR4A,TOR3A |
| 2.840e-02 | -3.56 | Iso_dh | pfam domains | PF00180 | 5 | 4 | 17795 | 5224 |
IDH3B,IDH3A,IDH1,IDH2 |
| 2.840e-02 | -3.56 | skin-lower_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-lower_leg-benign_melanocytic_nevus-Spitz | 22 | 11 | 16828 | 4835 |
TPM3,GOLGA5,BAP1,GNAQ,LSM14A,LMNA,PPFIBP1,HRAS,KIT,GNA11,TP53 |
| 2.840e-02 | -3.56 | skin-upper_arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_arm-other-atypical_Spitzoid_tumour | 22 | 11 | 16828 | 4835 |
GOLGA5,TPM3,LSM14A,GNAQ,BAP1,LMNA,PPFIBP1,TP53,KIT,GNA11,HRAS |
| 2.840e-02 | -3.56 | skin-knee-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-knee-benign_melanocytic_nevus-Spitz | 22 | 11 | 16828 | 4835 |
PPFIBP1,LMNA,TP53,KIT,GNA11,HRAS,GOLGA5,TPM3,LSM14A,GNAQ,BAP1 |
| 2.840e-02 | -3.56 | skin-face-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-face-benign_melanocytic_nevus-Spitz | 22 | 11 | 16828 | 4835 |
HRAS,GNAQ,BAP1,LSM14A,GOLGA5,GNA11,KIT,TP53,PPFIBP1,LMNA,TPM3 |
| 2.840e-02 | -3.56 | endometrium-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | endometrium-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 22 | 11 | 16828 | 4835 |
PPP2R1A,AKT1,JAK2,TP53,CTNNB1,KRAS,KIT,PTEN,SMARCB1,SF3B1,PIK3CA |
| 2.840e-02 | -3.56 | skin-buttock-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-buttock-other-atypical_Spitzoid_tumour | 22 | 11 | 16828 | 4835 |
HRAS,GOLGA5,BAP1,GNAQ,LSM14A,PPFIBP1,LMNA,GNA11,KIT,TP53,TPM3 |
| 2.840e-02 | -3.56 | skin-arm-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-arm-benign_melanocytic_nevus-Spitz | 22 | 11 | 16828 | 4835 |
LMNA,PPFIBP1,HRAS,GNA11,KIT,KRAS,TP53,TPM3,GOLGA5,GNAQ,LSM14A |
| 2.840e-02 | -3.56 | upper_aerodigestive_tract-head_neck-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma | 22 | 11 | 16828 | 4835 |
PIK3CA,DICER1,MET,SRSF2,TP53,TSHR,PTPN11,SF3B1,NFE2L2,SMAD4,KRAS |
| 2.840e-02 | -3.56 | skin-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-other-atypical_Spitzoid_tumour | 22 | 11 | 16828 | 4835 |
TPM3,GOLGA5,BAP1,GNAQ,LSM14A,PPFIBP1,LMNA,GNA11,HRAS,KIT,TP53 |
| 2.842e-02 | -3.56 | AMY1C (amylase alpha 1C) | protein interactions | 278 | 93 | 35 | 19454 | 5460 |
JAK2,ST3GAL5,PRKCE,B3GALNT1,MAB21L1,STARD3NL,MAGED2,CORO1C,SCAMP2,GYS1,GTF2B,WDR6,RIT1,STK11,CCDC174,VASH1,TTL,KLHL22,AMY2B,PLEKHO1,BAK1,KRAS,UCP2,NPB,AKAP1,CACUL1,SLC39A3,HINT2,RING1,RHOBTB1,E2F6,ARMCX3,MTCH2,TIMM10,STBD1 |
| 2.842e-02 | -3.56 | ZBED1 (zinc finger BED-type containing 1) | protein interactions | 9189 | 93 | 35 | 19454 | 5460 |
S100B,NCDN,ZNF451,PICK1,EFHC1,TTR,ZBED1,KDM1A,UBE2A,MBD3,PIAS1,PAX6,FANCG,MPST,FABP4,SUMO1,TULP3,CDK7,NHERF1,MTA2,NUDT18,ZHX1,UBE2I,SPEF1,ZNF576,MKKS,SUMO2,MAD2L2,FNDC11,USP2,NTAQ1,TTC23,GORASP2,NIF3L1,LRRC20 |
| 2.842e-02 | -3.56 | CDS2 (CDP-diacylglycerol synthase 2) | protein interactions | 8760 | 93 | 35 | 19454 | 5460 |
TMX2,LRRN4CL,VIPR1,TRIM63,SRPRB,HSCB,TNFSF8,HS2ST1,SLC6A8,PGRMC1,TP53,TIMMDC1,CCDC47,HCST,CNPY3,MGARP,YIPF3,AQP3,PTRH2,SIGMAR1,LMNA,SSMEM1,RNF122,CCNF,S1PR4,GPR173,TSG101,RMDN3,VIRMA,ESR2,SLMAP,TMEM45B,MYG1,RAMP3,CREB3 |
| 2.842e-02 | -3.56 | BCL7B (BAF chromatin remodeling complex subunit BCL7B) | protein interactions | 9275 | 93 | 35 | 19454 | 5460 |
BCL7C,SMARCE1,RACGAP1,AR,PSMD3,MYC,KPNA1,SMAD9,LHX2,ANKRD49,PSMC5,DOK4,PPIA,JUNB,TMEM248,SOX2,SMAD1,SAP30,RAF1,ACTL6A,MAPKAPK5,SMARCB1,NLRP2,RPRD1B,DMAP1,NUP50,RNF10,SMARCD3,LIN7C,S100B,PAX6,SS18,RIGI,NAT9,KPNA2 |
| 2.842e-02 | -3.56 | MAIP1 (matrix AAA peptidase interacting protein 1) | protein interactions | 79568 | 93 | 35 | 19454 | 5460 |
DDX39A,TIMMDC1,APOC2,NDUFA5,RPA2,PTPN22,HDAC11,NDUFS3,ABCE1,CLPB,MAIP1,RPA3,NDUFA4,CHCHD2,UFL1,NDUFS2,FBXW7,STOML2,PMPCA,NTRK3,DNAJC19,SPOP,APOC4,IRF2,DUSP6,PHB1,COX4I1,EGLN3,ATP5PD,NDUFAF4,MAD2L2,ESR2,SSH3,TIMM21,CPT2 |
| 2.842e-02 | -3.56 | ODR4 (odr-4 GPCR localization factor homolog) | protein interactions | 54953 | 93 | 35 | 19454 | 5460 |
ASIC1,DUOXA2,ILVBL,NUP35,LRRC3B,VIRMA,FAM177A1,COMT,RETREG3,CYBC1,AMIGO1,SEC61B,FAS,SPOP,SAYSD1,PSMD14,NAPA,TYROBP,REEP6,UBE2H,HM13,DDRGK1,NAPG,KRAS,UFL1,HSCB,NF2,GPM6A,RPA3,UBE2M,CCDC47,TP53,SEC62,OTULINL,FAXC |
| 2.846e-02 | -3.56 | protein serine/threonine kinase inhibitor activity | molecular function | GO:0030291 | 37 | 17 | 18094 | 5411 |
PKIA,PKIG,HEXIM1,CDKN2D,SFN,PPP1R1B,PKIB,MACROH2A1,SPRED2,CDKN1B,HEXIM2,SPRED1,YWHAG,AKT1,CDKN2C,HSPB1,CDKN1A |
| 2.846e-02 | -3.56 | acute_leukaemic_transformation_of_myeloproliferative_neoplasm | COSMIC cancer mutations | acute_leukaemic_transformation_of_myeloproliferative_neoplasm | 44 | 19 | 16828 | 4835 |
SF3B1,RUNX1,CALR,KRAS,HRAS,IDH1,JAK1,CBL,PTEN,EZH2,KIT,MET,SRSF2,TP53,AKT1,JAK2,PTPN11,IDH2,FBXW7 |
| 2.846e-02 | -3.56 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_myeloproliferative_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemic_transformation_of_myeloproliferative_neoplasm | 44 | 19 | 16828 | 4835 |
IDH2,FBXW7,PTPN11,JAK2,AKT1,TP53,SRSF2,KIT,MET,EZH2,PTEN,CBL,JAK1,IDH1,HRAS,KRAS,CALR,RUNX1,SF3B1 |
| 2.851e-02 | -3.56 | negative regulation of striated muscle cell differentiation | biological process | GO:0051154 | 43 | 19 | 18204 | 5365 |
HDAC3,CEACAM5,XBP1,FOXP1,RGS2,PI16,MIR222,DKK1,G6PD,MIR590,GSK3A,MSX1,HDAC5,TOMM70,CCN3,SMAD4,EZH2,CAV3,PPARA |
| 2.851e-02 | -3.56 | maintenance of protein localization in organelle | biological process | GO:0072595 | 43 | 19 | 18204 | 5365 |
TSPO,HSPA5,RER1,PML,AKT1,ARL2BP,OS9,GPAA1,CDK5,PGR,KDELR2,KDELR1,PDIA2,TOPORS,TXN,SKP1,FKRP,SUPT7L,INSIG2 |
| 2.852e-02 | -3.56 | nucleoside diphosphate metabolic process | biological process | GO:0009132 | 83 | 33 | 18204 | 5365 |
NUDT5,LDHA,GUK1,OGDHL,HTR2A,PGAM1,ENTPD4,ENO1,AK5,LIPA,PGK1,FKRP,PFKFB2,UMPS,DLG1,MPP1,NUDT7,BPGM,DTYMK,ENO2,UCP2,CASK,AK2,NUDT9,RRM1,ENTPD3,GAPDH,NUDT18,IER3,PGM1,CMPK1,BAD,AK3 |
| 2.857e-02 | -3.56 | USP54 (ubiquitin specific peptidase 54) | protein interactions | 159195 | 207 | 71 | 19454 | 5460 |
ATG16L1,DET1,LMO3,OIP5,CRYL1,CHMP2B,TRIM52,ASB3,P4HA2,RNF113A,RAMAC,CCT2,BICD2,DCAF4,YWHAZ,FBXW11,EPHA2,EXOC8,ARMC7,CDC16,VPS39,HNF1B,SFN,SNRPB,RHOBTB3,AR,KCTD9,PRRC2A,VIRMA,DYRK1A,RNF208,ATXN1L,ANAPC2,RP9,CHMP4C,PNMA2,DISC1,CAPN2,STK16,HGS,RAF1,TNRC6C,TRAF2,LGR4,CHCHD2,CHMP1B,HNRNPF,TOLLIP,PHF1,FLOT1,SNIP1,BHLHE40,TCEA2,GARRE1,NXT2,CDC23,YWHAB,PLAC8,USP2,YWHAH,CPEB1,SHC3,YWHAG,CSNK2A1,CTNNB1,EGLN3,CHMP2A,DOK6,EIF4E2,FUBP3,OLFM2 |
| 2.858e-02 | -3.56 | IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker)) | protein interactions | 3501 | 121 | 44 | 19454 | 5460 |
RNF115,MSL2,EGFL8,HSD17B10,CCR1,PDE6D,CA8,KHDC4,TP53,FCF1,FZR1,FUNDC2,STK3,NRSN1,ARL2BP,AHSA1,UPK1A,AGPAT1,SAV1,EMC4,PTDSS1,SCGB1D1,STK4,DDRGK1,UFL1,HSPA5,HSPA8,PMAIP1,CYP3A5,METTL14,STX17,STAMBP,UBE2M,AKR1A1,SSBP2,PLSCR4,CCNA2,CDK7,ALB,ASCC1,CCT2,UBE2H,MORF4L1,USP14 |
| 2.874e-02 | -3.55 | transcription coregulator binding | molecular function | GO:0001221 | 114 | 44 | 18094 | 5411 |
PHF12,SMAD3,ZBTB16,EZH2,STAT6,HDAC5,ZBTB17,CBX3,PAX6,THAP7,EED,EP300,NFE2L2,HDAC3,UBE2I,AR,CDK9,CTNNB1,FAM89B,SMAD4,VGLL4,CREBBP,LMO2,MYC,CTBP1,TERT,PGR,PPARG,HDAC6,RPL23,CREB3,ELOC,FOS,BCL6,KLF4,ENO1,SP1,CNOT2,PHF1,STAT1,HAND2,SMARCD3,PPARA,HMGA1 |
| 2.878e-02 | -3.55 | lipoprotein transport | biological process | GO:0042953 | 19 | 10 | 18204 | 5365 |
SAR1B,MIR301B,MIR130B,PRKCB,SURF4,UNC119B,PPARG,ZDHHC17,CD36,VMP1 |
| 2.878e-02 | -3.55 | fibroblast migration | biological process | GO:0010761 | 19 | 10 | 18204 | 5365 |
CCN3,MACIR,NHERF1,ILK,PIP5K1A,CD248,FUT8,AKT1,PML,LAMTOR2 |
| 2.878e-02 | -3.55 | regulation of B cell apoptotic process | biological process | GO:0002902 | 19 | 10 | 18204 | 5365 |
SLC39A10,BCL10,BCL6,IL10,BAX,FOXP1,ORMDL3,IL2,MIF,PDCD1 |
| 2.878e-02 | -3.55 | negative regulation of alcohol biosynthetic process | biological process | GO:1902931 | 19 | 10 | 18204 | 5365 |
ERLIN2,DKK3,CYP27B1,SOD1,MIR185,MIR342,NFKB1,GFI1,ERLIN1,MIR98 |
| 2.878e-02 | -3.55 | nucleotide-sugar biosynthetic process | biological process | GO:0009226 | 19 | 10 | 18204 | 5365 |
UGDH,GFUS,GMPPB,PMM2,UAP1,GNPDA1,GNPNAT1,GMDS,GFPT1,GNPDA2 |
| 2.878e-02 | -3.55 | positive regulation of transforming growth factor beta production | biological process | GO:0071636 | 19 | 10 | 18204 | 5365 |
XCL1,ATP6AP2,CD200,CX3CL1,BMPR1A,SMAD3,FOXP3,LUM,CD46,MIR149 |
| 2.878e-02 | -3.55 | response to hydroperoxide | biological process | GO:0033194 | 19 | 10 | 18204 | 5365 |
JAK2,SIN3A,CD36,GPX3,TMIGD1,CD38,TP53INP1,SP1,GPX1,DAPK1 |
| 2.878e-02 | -3.55 | long-term synaptic depression | biological process | GO:0060292 | 19 | 10 | 18204 | 5365 |
GRIA1,STXBP1,PICK1,DRD1,ABHD6,CD38,GRM2,PRRT1,ARF1,ADORA1 |
| 2.878e-02 | -3.55 | RIPK2 (receptor interacting serine/threonine kinase 2) | protein interactions | 8767 | 90 | 34 | 19454 | 5460 |
PHB2,TMUB1,TLR4,CD40,SQSTM1,MAVS,TLR2,BIRC2,KCTD12,TAB2,PPP1R8,ATG16L1,RPS14,ERLIN2,PRMT2,TRAF2,TAB1,FBXO22,TRAF1,SMURF1,ERLIN1,UBE2I,CASP12,BECN1,TRAF6,BCL10,PELI3,SMAD4,YWHAB,CUL3,IRF4,MOV10,YWHAG,YWHAH |
| 2.878e-02 | -3.55 | MBD6 (methyl-CpG binding domain protein 6) | protein interactions | 114785 | 90 | 34 | 19454 | 5460 |
CFL1,DPY30,MORF4L1,HNF1B,HNRNPD,H1-10,HP1BP3,ATXN1L,SRSF1,RPS3,CCT7,TMPO,MAT2B,PPIA,LYAR,SNRPD3,SNRPA1,DYNLL1,HNRNPL,TXN,RPS16,LBR,CCT5,TOP3B,JUP,KLF3,DDX5,H2BC12,SLC25A5,BAP1,SKP1,RPS4X,KPNA2,CHCHD2 |
| 2.878e-02 | -3.55 | BRIP1 (BRCA1 interacting helicase 1) | protein interactions | 83990 | 90 | 34 | 19454 | 5460 |
GFOD1,SNRNP40,APEX1,CREBBP,CUL3,CIAO3,CIAO1,HNRNPC,HDAC6,NOL4,SNAP91,BRCA1,PSMD14,STK11,COP1,TOPBP1,RPA3,NBN,PSME1,NUP50,FHL3,NF2,HDAC3,H3C1,SLC31A1,CRYL1,ASF1A,TRIM52,PTGES3,RPA2,LMNA,VAPB,CDK8,CBX3 |
| 2.878e-02 | -3.55 | CDKN2C (cyclin dependent kinase inhibitor 2C) | protein interactions | 1031 | 90 | 34 | 19454 | 5460 |
MYC,AKT1,CDKN2D,TLE1,DRAP1,QPCTL,AK2,NIF3L1,LY96,STK11,EPHA2,SLX1A,ACOX1,CCDC90B,CDK6,NAT2,GRM1,LRIF1,LNX2,MTA3,RAF1,CDK4,CCND1,TP53,MAP2K3,MAPK10,CARTPT,CTDSP1,EZH2,PYM1,GPSM3,NF2,AHCYL1,CCND3 |
| 2.879e-02 | -3.55 | human chr12q22 | chromosome location | human chr12q22 | 31 | 12 | 26134 | 5823 |
NUDT4,NDUFA12,CRADD,VEZT,NTN4,MIR492,UBE2N,METAP2,MIR331,PLXNC1,CLLU1,SOCS2 |
| 2.881e-02 | -3.55 | deoxyribonucleoside diphosphate metabolic process | biological process | GO:0009186 | 5 | 4 | 18204 | 5365 |
NUDT18,DTYMK,AK5,GUK1 |
| 2.881e-02 | -3.55 | negative regulation of chondrocyte proliferation | biological process | GO:1902731 | 5 | 4 | 18204 | 5365 |
CCN3,MIR21,BMPR1B,BMPR2 |
| 2.881e-02 | -3.55 | tricuspid valve morphogenesis | biological process | GO:0003186 | 5 | 4 | 18204 | 5365 |
HEY2,TGFBR2,BMPR1A,BMPR2 |
| 2.881e-02 | -3.55 | putrescine biosynthetic process | biological process | GO:0009446 | 5 | 4 | 18204 | 5365 |
PAOX,AZIN1,ODC1,AZIN2 |
| 2.881e-02 | -3.55 | regulation of membrane depolarization during cardiac muscle cell action potential | biological process | GO:1900825 | 5 | 4 | 18204 | 5365 |
CAV3,RANGRF,SLMAP,MIR208A |
| 2.881e-02 | -3.55 | RNA localization to nucleus | biological process | GO:0090685 | 5 | 4 | 18204 | 5365 |
CCT2,TCP1,DKC1,WRAP53 |
| 2.881e-02 | -3.55 | regulation of IP-10 production | biological process | GO:0071658 | 5 | 4 | 18204 | 5365 |
OAS1,LILRB4,MAVS,MIR34A |
| 2.881e-02 | -3.55 | regulation of core promoter binding | biological process | GO:1904796 | 5 | 4 | 18204 | 5365 |
GTF2B,PSEN1,PAX6,IFNG |
| 2.881e-02 | -3.55 | negative regulation of myosin-light-chain-phosphatase activity | biological process | GO:0035509 | 5 | 4 | 18204 | 5365 |
ROCK2,TNF,IKBKB,ROCK1 |
| 2.881e-02 | -3.55 | central nervous system myelin maintenance | biological process | GO:0032286 | 5 | 4 | 18204 | 5365 |
MYRF,CLU,FA2H,PTEN |
| 2.881e-02 | -3.55 | eosinophil activation | biological process | GO:0043307 | 5 | 4 | 18204 | 5365 |
CCL3,VAMP8,VAMP2,VAMP7 |
| 2.881e-02 | -3.55 | regulation of vesicle transport along microtubule | biological process | GO:1901608 | 5 | 4 | 18204 | 5365 |
MECP2,TRIM46,BORCS5,STK11 |
| 2.881e-02 | -3.55 | autophagic cell death | biological process | GO:0048102 | 5 | 4 | 18204 | 5365 |
CDKN1B,SH3GLB1,TP53INP1,CDKN2D |
| 2.881e-02 | -3.55 | regulation of corticotropin secretion | biological process | GO:0051459 | 5 | 4 | 18204 | 5365 |
GHRL,CRHBP,UCN,RAB8B |
| 2.881e-02 | -3.55 | positive regulation of vesicle transport along microtubule | biological process | GO:1901610 | 5 | 4 | 18204 | 5365 |
BORCS5,TRIM46,MECP2,STK11 |
| 2.881e-02 | -3.55 | purine deoxyribonucleotide biosynthetic process | biological process | GO:0009153 | 5 | 4 | 18204 | 5365 |
ADK,DCK,GUK1,AK5 |
| 2.881e-02 | -3.55 | activation of protein kinase C activity | biological process | GO:1990051 | 5 | 4 | 18204 | 5365 |
LEP,PHB1,PHB2,CD86 |
| 2.881e-02 | -3.55 | membrane tubulation | biological process | GO:0097749 | 5 | 4 | 18204 | 5365 |
CIBAR1,CORO1C,TMCC1,DNM2 |
| 2.881e-02 | -3.55 | conditioned place preference | biological process | GO:1990708 | 5 | 4 | 18204 | 5365 |
OPRL1,OPRK1,SLC1A1,SLC6A4 |
| 2.881e-02 | -3.55 | cellular response to indole-3-methanol | biological process | GO:0071681 | 5 | 4 | 18204 | 5365 |
JUP,CTNNA1,CTNNB1,BRCA1 |
| 2.881e-02 | -3.55 | eosinophil degranulation | biological process | GO:0043308 | 5 | 4 | 18204 | 5365 |
VAMP8,VAMP2,VAMP7,CCL3 |
| 2.881e-02 | -3.55 | eosinophil activation involved in immune response | biological process | GO:0002278 | 5 | 4 | 18204 | 5365 |
CCL3,VAMP8,VAMP7,VAMP2 |
| 2.881e-02 | -3.55 | regulation of plasma cell differentiation | biological process | GO:1900098 | 5 | 4 | 18204 | 5365 |
XBP1,BCL6,IL2,IL10 |
| 2.881e-02 | -3.55 | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration | biological process | GO:0014834 | 5 | 4 | 18204 | 5365 |
SELENON,EZH2,WNT7A,IGF1 |
| 2.881e-02 | -3.55 | RNA localization to Cajal body | biological process | GO:0090670 | 5 | 4 | 18204 | 5365 |
DKC1,CCT2,TCP1,WRAP53 |
| 2.881e-02 | -3.55 | scaRNA localization to Cajal body | biological process | GO:0090666 | 5 | 4 | 18204 | 5365 |
WRAP53,TCP1,CCT2,DKC1 |
| 2.881e-02 | -3.55 | hindbrain maturation | biological process | GO:0021578 | 5 | 4 | 18204 | 5365 |
CEND1,ARCN1,RERE,CDK5R1 |
| 2.881e-02 | -3.55 | negative regulation of vitamin D biosynthetic process | biological process | GO:0010957 | 5 | 4 | 18204 | 5365 |
SNAI2,CYP27B1,GFI1,NFKB1 |
| 2.881e-02 | -3.55 | regulation of electron transfer activity | biological process | GO:1904732 | 5 | 4 | 18204 | 5365 |
NDUFA4,SPHK2,PHB2,COX17 |
| 2.881e-02 | -3.55 | transforming growth factor beta production | biological process | GO:0071604 | 5 | 4 | 18204 | 5365 |
COL3A1,ITGAV,CD2AP,FOXP3 |
| 2.881e-02 | -3.55 | NLRP3 inflammasome complex assembly | biological process | GO:0044546 | 5 | 4 | 18204 | 5365 |
KCNJ8,PYCARD,NLRP3,ATAT1 |
| 2.881e-02 | -3.55 | phenotypic switching | biological process | GO:0036166 | 5 | 4 | 18204 | 5365 |
MIR21,MIR143,MIR145,MIR1-1 |
| 2.881e-02 | -3.55 | negative regulation of interleukin-1 alpha production | biological process | GO:0032690 | 5 | 4 | 18204 | 5365 |
MIR142,IL1R2,MIR181C,CX3CL1 |
| 2.881e-02 | -3.55 | positive regulation of sulfur metabolic process | biological process | GO:0051176 | 5 | 4 | 18204 | 5365 |
NFE2L2,CTNNB1,PXYLP1,SP1 |
| 2.881e-02 | -3.55 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway | biological process | GO:0071878 | 5 | 4 | 18204 | 5365 |
PDE4B,ATP2B4,ARRDC3,GNAI2 |
| 2.881e-02 | -3.55 | response to L-ascorbic acid | biological process | GO:0033591 | 5 | 4 | 18204 | 5365 |
IL1A,SOD2,LEP,ITGA2 |
| 2.881e-02 | -3.55 | negative regulation of receptor recycling | biological process | GO:0001920 | 5 | 4 | 18204 | 5365 |
PCSK9,AP1AR,LDLR,OPTN |
| 2.881e-02 | -3.55 | regulation of antifungal innate immune response | biological process | GO:1905034 | 5 | 4 | 18204 | 5365 |
USP15,PLA2G5,FAM3A,TRIM62 |
| 2.881e-02 | -3.55 | positive regulation of toll-like receptor 9 signaling pathway | biological process | GO:0034165 | 5 | 4 | 18204 | 5365 |
HMGB1,TLR9,RSAD2,RTN4 |
| 2.881e-02 | -3.55 | regulation of ferroptosis | biological process | GO:0110075 | 5 | 4 | 18204 | 5365 |
SLC7A11,SLC39A7,GPX4,TMEM164 |
| 2.881e-02 | -3.55 | regulation of cytochrome-c oxidase activity | biological process | GO:1904959 | 5 | 4 | 18204 | 5365 |
NDUFA4,SPHK2,PHB2,COX17 |
| 2.881e-02 | -3.55 | activation of meiosis | biological process | GO:0090427 | 5 | 4 | 18204 | 5365 |
PLCB1,NPR2,MSX2,MSX1 |
| 2.884e-02 | -3.55 | RASSF2 (Ras association domain family member 2) | protein interactions | 9770 | 45 | 19 | 19454 | 5460 |
YWHAG,CNPY3,YWHAH,HDAC6,SUV39H1,STK4,PRMT6,SAV1,SFN,YWHAB,PPP3CA,YWHAZ,PTEN,HRAS,VIRMA,JAK2,STK3,KRAS,KDM1A |
| 2.884e-02 | -3.55 | SEPTIN1 (septin 1) | protein interactions | 1731 | 45 | 19 | 19454 | 5460 |
H1-5,DDIT4L,HMGA1,GORASP2,MRPL12,H2BC9,H2AC4,SDCBP,NIF3L1,PIH1D1,ASB7,SEPTIN6,UBE2I,HAPSTR1,SEPTIN7,PICK1,TOLLIP,FBXO22,RAD21 |
| 2.884e-02 | -3.55 | CPNE4 (copine 4) | protein interactions | 131034 | 45 | 19 | 19454 | 5460 |
RPL26L1,PHOSPHO2,UBE2M,H1-1,ANKRD49,NACC2,FTSJ3,CCDC22,MAP2K1,SPTBN1,SUPT5H,RPS27A,PPP5C,GTF3C3,RSL24D1,CPNE1,STAU1,ACTB,RPL3 |
| 2.884e-02 | -3.55 | GFRA1 (GDNF family receptor alpha 1) | protein interactions | 2674 | 45 | 19 | 19454 | 5460 |
SNX5,KIF2A,BAG3,DDX39A,SOCS3,TSN,TTC4,HNRNPK,GTF2I,SPPL3,TFG,HNRNPDL,ESR2,RNF20,PSME1,PSMB5,AIFM1,RAB1A,DDX5 |
| 2.884e-02 | -3.55 | C1orf174 (chromosome 1 open reading frame 174) | protein interactions | 339448 | 45 | 19 | 19454 | 5460 |
RIOX2,AKT1,RAF1,H2AX,XPO1,DDX39A,PALS2,BLVRA,BRD3,PARP2,LIN7C,MACROH2A1,EEF1G,H3C1,AHCYL1,ESR2,EGLN3,KLK3,CBX5 |
| 2.884e-02 | -3.55 | CASKIN2 (CASK interacting protein 2) | protein interactions | 57513 | 45 | 19 | 19454 | 5460 |
APEX1,CAV1,FLOT1,VIRMA,ESR2,STX7,RHOJ,PRNP,KRAS,GJA1,HRAS,RAB35,RHOU,NCK1,LAMTOR1,VPS33A,DNAJC5,YWHAG,YWHAH |
| 2.884e-02 | -3.55 | SLITRK5 (SLIT and NTRK like family member 5) | protein interactions | 26050 | 45 | 19 | 19454 | 5460 |
ATP1B1,CDC42,RND2,ATG9A,PLD3,RND3,RHOB,RHOG,RAC2,HAPSTR1,TAS1R2,RHOU,VIRMA,RHOJ,BOLA2B,RHOH,PSMA5,STAT1,KRAS |
| 2.884e-02 | -3.55 | BAK1 (BCL2 antagonist/killer 1) | protein interactions | 578 | 45 | 19 | 19454 | 5460 |
BOK,MCL1,NFKBIB,BAD,VDAC2,HSPD1,DFFA,BCL2A1,BNIP3L,VIRMA,VDAC1,MFN1,TOMM40,TOMM7,BAK1,TP53,BCL2L1,BAX,ACTR2 |
| 2.884e-02 | -3.55 | ZNF8 (zinc finger protein 8) | protein interactions | 7554 | 45 | 19 | 19454 | 5460 |
KDM1A,MAD2L1,AP1M1,CBX5,PTP4A3,VIRMA,SMAD5,SMAD3,FBLN5,ZNF330,INTS12,PHF21A,SMAD4,CBX3,CHMP1A,SMAD2,CUL3,SMAD1,METTL15 |
| 2.884e-02 | -3.55 | HERPUD1 (homocysteine inducible ER protein with ubiquitin like domain 1) | protein interactions | 9709 | 45 | 19 | 19454 | 5460 |
SIAH1,TOLLIP,DERL2,IL23A,CCR2,IMPA2,PSEN1,LMBR1L,DERL1,EWSR1,SYVN1,CGRRF1,RPN1,RPA2,CD58,FAM8A1,SELENOS,TBK1,ATG9A |
| 2.884e-02 | -3.55 | ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1) | protein interactions | 116985 | 45 | 19 | 19454 | 5460 |
SHC1,CAPZA2,ARPC3,NCK1,KCTD12,SMAD4,DNAJB6,UBXN6,TOP3B,CDC42,TAB1,HNRNPL,CAPZA1,RIGI,EEF1AKMT3,RPL9,CCNF,TES,UBASH3B |
| 2.884e-02 | -3.55 | ORC6 (origin recognition complex subunit 6) | protein interactions | 23594 | 45 | 19 | 19454 | 5460 |
MCM6,CDC5L,LRWD1,CREB1,PSPC1,S100B,DCTN6,XRCC5,CDC7,BCL9,BICD2,SSBP3,HMGA1,SSBP2,ORC5,PPIL4,LDB1,LMO4,MCM4 |
| 2.889e-02 | -3.54 | HULC (hepatocellular carcinoma up-regulated long non-coding RNA) | protein interactions | 728655 | 159 | 56 | 19454 | 5460 |
LDHB,PYCR2,NONO,GMNN,IVNS1ABP,CCT2,ANAPC4,PELP1,RETREG3,LDHA,SEC63,GNAI2,EDEM3,LARP4B,FGFR1,HSP90B1,SDCBP,DCTN4,MFAP1,NUFIP2,PML,SQSTM1,SMG5,P4HA2,TAPBP,GPHN,HSPA8,MRPL40,NAPG,GTF2I,IFIH1,DDX50,H2AC14,PDIA3,PPFIBP1,ECD,CNN3,FUBP3,IFIT2,MGME1,SEC23A,CDC5L,SLMAP,RPS7,KIF2A,BLOC1S3,RPAP2,TFCP2,VPS33A,ROCK2,L1CAM,DHX16,RAD21,RIGI,SSRP1,PSMB10 |
| 2.893e-02 | -3.54 | IL12-mediated signaling events | Pathway Interaction DB | il12_2pathway | 61 | 29 | 2226 | 782 |
STAT1,CCL3,JAK2,GADD45B,SPHK2,CD247,CCR5,IL18,IL4,IL2RG,B2M,IFNG,IL2RA,IL1B,GADD45G,NFKB1,STAT6,CD4,MAP2K3,STAT5A,MAP2K6,FOS,CCL4L1,CD3G,FASLG,IL12A,IL2,IL12B,IL2RB |
| 2.893e-02 | -3.54 | MITOCARRIER | prints domains | PR00926 | 27 | 13 | 5227 | 1528 |
SLC25A42,SLC25A45,SLC25A44,SLC25A23,SLC25A24,SLC25A21,SLC25A31,SLC25A4,SLC25A39,SLC25A1,SLC25A5,SLC25A17,SLC25A12 |
| 2.902e-02 | -3.54 | BPTF (bromodomain PHD finger transcription factor) | protein interactions | 2186 | 175 | 61 | 19454 | 5460 |
MTA3,TP53,H2AX,AURKAIP1,SOX2,SAP30,ELF1,EZH2,NFE2L2,MTA2,PPP1R12A,BAG2,HUWE1,RBBP7,H3C1,MRPL22,SRSF4,RPS4X,PHF1,PAX6,DPY30,KPNA1,POU5F1,BRD3,H2AZ1,SIN3A,SMAD3,MYBL2,EED,GATAD1,HNRNPL,PGR,SHPRH,SUMO2,BRMS1L,TIMM13,RFXANK,KLF3,RPA2,RPA3,SIRT7,SQSTM1,IL1A,MBD3,SMARCA5,MYC,HNF1B,H2BC9,BRCA1,SMAD2,CALU,PHF12,DLST,MACROH2A1,RBBP4,TAX1BP1,MAD2L1,DEK,APEX1,ESR2,VIRMA |
| 2.902e-02 | -3.54 | IDE (insulin degrading enzyme) | protein interactions | 3416 | 175 | 61 | 19454 | 5460 |
FASTKD5,IGF1,DCP2,TSSC4,CHCHD2,OPA3,PSME1,ILDR1,DOHH,FAM136A,NEFL,SMNDC1,GPAM,PROK1,SOX2,TP53,SPPL3,HNRNPL,INA,COMT,DEFB1,AIFM1,PPM1K,DDX1,CHCHD1,H2AC4,DLK2,IFIH1,NSFL1C,PAFAH1B2,ARFIP1,MIA2,HSPA8,RPA3,PAK5,RPA2,SPRYD4,RPE,SHMT1,ATP6V1C1,ESR2,CCL23,TENT5C,STAT1,LDHA,PTEN,LURAP1,CTTN,UQCRC2,UBE2H,PHF7,AR,ATP5F1A,LDHB,FAM163B,HNRNPAB,MRM2,CSK,NIBAN2,CACNB4,CARS1 |
| 2.902e-02 | -3.54 | PKN3 (protein kinase N3) | protein interactions | 29941 | 175 | 61 | 19454 | 5460 |
HMG20A,HSP90AB1,NUF2,PPIA,CX3CL1,PPP2CB,RPRD1A,WDR6,AIP,TESK1,AKAP8L,HAX1,HNRNPD,TUBG1,NGDN,FEM1B,INSYN1,HDAC6,FKBP8,UBE2A,TGFBR2,CAMK2G,SKA1,EFNB1,RPAP3,TFPT,PNMA2,CCDC122,NUDCD3,MAX,TOP3B,POLR2B,MANSC1,TRIM29,PHF21A,MOB4,LURAP1,PNMA1,STUB1,CCNF,S100A6,CCHCR1,HSP90AA1,RHOB,PIK3R2,OIP5,P4HA2,HNRNPH2,SPECC1L,ATP5MK,PIH1D1,GIT2,TFIP11,AVPR1B,SSR1,GOLGA5,CNP,SLC35E1,HCST,RBFOX2,NUP62 |
| 2.902e-02 | -3.54 | EFNB2 (ephrin B2) | protein interactions | 1948 | 140 | 50 | 19454 | 5460 |
KRAS,EPHA4,PSEN1,EFNB1,PICK1,RPN1,PIK3CA,TSPAN3,RND3,TP53,RHOH,EIF2B2,EIF2B5,GRM1,HNRNPL,ARF6,ANKRD46,CAV1,CD28,STX6,EPHB6,DIRAS3,HRAS,RAB35,GJA1,NUS1,RAB5C,PIK3R1,LAMP2,LAMP3,PIK3R2,STX7,DAD1,RAB5A,SDC2,SDCBP,ARL15,CDC42,RHOJ,SRC,HOMER1,DLG4,SEC61B,RHOB,LAMTOR1,RAB11A,PIK3R3,RAB2A,RETSAT,DNAJC5 |
| 2.905e-02 | -3.54 | Translocation of GLUT4 to the plasma membrane | REACTOME pathways | R-HSA-1445148 | 62 | 27 | 10285 | 3229 |
EXOC2,RAB14,TBC1D4,EXOC8,MYH1,EXOC1,YWHAH,RAB11A,YWHAZ,PRKAB1,MYH2,EXOC3,YWHAG,AKT2,SFN,RAB4A,RAB13,VAMP2,AKT1,SNAP23,TBC1D1,YWHAB,RALGAPA2,RALA,KIF3B,PRKAG1,EXOC5 |
| 2.907e-02 | -3.54 | YTHDC1 (YTH N6-methyladenosine RNA binding protein C1) | protein interactions | 91746 | 414 | 134 | 19454 | 5460 |
E2F4,PAIP2B,FAF2,PPP2R1A,ISG15,ZNF526,EZH2,RPL31,SLC25A23,TRIM11,SRSF7,PICK1,SATB1,NUP42,ZNF592,NAB1,USP30,H1-6,KRAS,SSRP1,SRSF4,PFDN5,PCNX1,IFI16,TRA2A,EIF3D,HNRNPA1,SKIC8,FOSL2,DDX23,ZNF175,ANKRD50,MAGOH,CAMSAP2,RB1CC1,VCPIP1,SRSF1,TRAM2,FBXO32,CCDC71,COPS2,SNRPD3,TMEM170A,SSBP2,PABPC5,RALYL,LARP4B,PCLAF,SNRK,NKAPD1,DDX39B,SNRPA,MACIR,UFL1,UBE2D3,SRSF2,TRA2B,FTL,COIL,SAP18,HNRNPC,ST3GAL2,MYC,SNRPB,RNF40,DCAF4,FBXW11,RIT1,ARMC7,BOLA1,ZNF862,VPS72,DLST,SNRNP40,DTD2,ESR2,RPL19,APEX1,NDUFA2,TP53,APOBEC3D,EXOC3,TAF2,ILF2,SNIP1,RPL23A,ZC3H11A,MIR223,HNRNPK,MSH6,CDC42SE1,PHYKPL,SETD5,GTF2E1,SNRNP70,TTL,FOXP1,ZNF688,DFFA,PRR3,TOP1,PLG,SLAIN2,TLR6,ZBTB2,MDM2,TMPO,STX6,ATG16L1,RBMS2,RNF103,RPA2,RPA3,TNFAIP1,KLHL28,CLK1,ADAMTS10,PEX26,TAF5L,RUNX1,RC3H2,ZSWIM7,ELAVL2,ZNF330,RNF122,EIF4A3,RPS3,ADGRL3,CSNK2B,TXNDC12,SRPK2,SRC,ACP2,PPP1R10 |
| 2.909e-02 | -3.54 | positive regulation of organelle organization | biological process | GO:0010638 | 503 | 168 | 18204 | 5365 |
RALA,CNOT6L,NCK1,RPS3,SLAIN2,CCL24,RUVBL1,MAP1B,NPR2,MSX1,BAK1,SLC25A4,TRIM32,CTNNB1,HNRNPD,OSBP,BOK,ROCK2,MUL1,SMAD3,SNX18,CX3CL1,IL1A,CNOT2,SMC4,TNF,DKC1,IGF1,WASF3,TAPT1,INO80E,ADRB2,DRD3,PYCARD,CCT7,ZNF304,PROX1,CCT8,TMED9,PIWIL2,CCR7,S100A10,SEMA5A,VPS4B,TGFB3,IL1B,RALB,INO80C,STUB1,SLC25A5,LCP1,RB1,CTTN,BAD,GSK3A,PRKCE,TESK1,DRG1,PLA2G5,MACROH2A1,ANAPC11,NRP1,NUP62,PKIB,PML,MAPKAPK5,SH3GLB1,NCKAP1,IL5,CCT2,PFDN2,DLG1,CNOT6,CDC42EP3,MSN,XRCC5,ATP5IF1,FIS1,ARF6,BECN1,PIP4K2C,FEN1,MLLT11,MET,CCL21,LMAN1,CDC42EP2,NEK2,TOM1,MIEF1,CDC20,CFL2,CDC42,NEK7,MMP9,SFRP1,MIR1-1,SURF4,BAX,FERMT2,TP53,HNRNPA1,CDC16,CDC23,G3BP2,FCHSD2,G3BP1,TNFSF10,SDC4,LPAR1,CD47,SDCBP,TRIM27,STX18,WDR45,SLX1A,TFPT,HNRNPA2B1,CDK5R1,CCL11,CSF2,MARCHF5,CDK1,VDAC1,SSBP1,SRC,FAM162A,MORC2,PSRC1,ACTL6A,PDCD5,RUVBL2,CAV3,ADCK1,NCAPG2,NF2,KCTD17,MNS1,SEPTIN7,CD28,CAPG,CDC42EP4,PMAIP1,SWAP70,MAD2L1BP,MECP2,TNKS,ARPC2,FBXO7,MCOLN1,RAD21,GPR65,PPP1R10,TNKS2,NBN,DSTN,CCT5,MSX2,STMN2,TCP1,UBE2B,RGCC,MAPRE1,PRKCQ,TACR1,CUL3,CDKN1B,PLCB1 |
| 2.911e-02 | -3.54 | SLC22A9 (solute carrier family 22 member 9) | protein interactions | 114571 | 118 | 43 | 19454 | 5460 |
SLC16A10,SLC19A2,SYNGR2,GHITM,UBAC2,TMEM115,TMEM184B,PIGW,FAM8A1,TSPAN15,ORMDL1,INPPL1,SYVN1,SLC25A51,MFSD3,CERS6,TM9SF4,ATP1A3,GGCX,GPR89A,SERINC1,SC5D,SLC29A1,YIPF4,NHERF1,RAB4A,SURF4,DHRS7B,TMEM87A,RUSF1,SCD5,SACM1L,SLC25A46,ORMDL3,FITM2,SLC20A1,ACSL4,MFSD5,SPPL3,ARL6IP5,CAV1,TLCD4,EXTL2 |
| 2.911e-02 | -3.54 | ALDH7A1 (aldehyde dehydrogenase 7 family member A1) | protein interactions | 501 | 118 | 43 | 19454 | 5460 |
PRDX6,HSPA8,BAP1,SOD1,RPA3,EMC1,FKBP1A,RPA2,FERMT2,MYG1,SUCLG2,ACTB,CPT2,AKR1C2,COPE,CFL1,LDHB,EPS8,MYC,CTSD,SORD,ATP1A1,S100A11,STK24,RC3H2,EMC2,SCPEP1,SIKE1,TFPT,KIF2A,CD2BP2,MAP1LC3B,SOD2,CAPN2,PDHA1,G6PD,NUP35,PPIA,DYNC1I2,COPS5,YWHAG,YWHAH,GSTO1 |
| 2.911e-02 | -3.54 | SIPA1L2 (signal induced proliferation associated 1 like 2) | protein interactions | 57568 | 118 | 43 | 19454 | 5460 |
SSX2IP,POU5F1,YWHAB,ORC5,DYRK1B,YWHAH,YWHAG,CTNNB1,MIF,EGLN3,NRSN1,GJA1,KRT8,TOP3B,SOX2,APOBEC3D,KRAS,UNC119B,RPL28,RNF20,FLOT1,ZYX,GARRE1,RHOB,FBXW11,YWHAZ,SNX5,SFN,CUL3,RACGAP1,ACTB,RPGRIP1L,VIRMA,ESR2,DYRK1A,CCNF,GSK3A,ANAPC2,TOMM22,SIPA1L1,BORCS6,STX7,TRIM52 |
| 2.912e-02 | -3.54 | ADPGK (ADP dependent glucokinase) | protein interactions | 83440 | 87 | 33 | 19454 | 5460 |
GXYLT1,CCNF,SEC61B,MGAT1,TCAP,ARMC6,TOR1B,EXTL2,APEX1,NUP35,CSGALNACT2,HMOX2,TADA3,TMEM30A,RNF139,C1GALT1C1,ST3GAL4,RPA3,RUSF1,TIMP3,TMEM106B,DPAGT1,HSCB,EMC1,B4GALT7,STX7,CCDC47,CNPY3,CLEC2B,GALNT4,RPA2,LMNA,STX12 |
| 2.912e-02 | -3.54 | MICA (MHC class I polypeptide-related sequence A) | protein interactions | 100507436 | 87 | 33 | 19454 | 5460 |
TNPO2,EDDM3B,VAC14,VIPR1,RAB13,TMEM87A,TMEM106B,ITM2B,CLDND1,AP1M1,TNFSF8,LCN9,ERLEC1,GPIHBP1,SCGB1D1,HDAC6,GGH,HMOX2,MICB,VAMP5,PHF7,TAFAZZIN,NCR3LG1,RPS6KA4,PRSS8,DNASE1L1,IL2RA,S1PR4,ELSPBP1,RAB35,VAMP3,TNPO3,MSMO1 |
| 2.912e-02 | -3.54 | NUCB1 (nucleobindin 1) | protein interactions | 4924 | 87 | 33 | 19454 | 5460 |
MGARP,HINT3,EZH2,GNAI3,GNAZ,RAD23B,TMEM106B,FGF3,XPNPEP1,DNAJC30,VRK1,GTF2I,HSPA5,RIGI,FAM20C,MYC,CHST13,DPP4,DNAJC8,XPO1,CYP1A1,DNAJC10,CALU,BRD3,SEC61B,GNAO1,TXNRD3,MANSC1,NDN,DYRK1A,APEX1,GNAI2,EGLN3 |
| 2.912e-02 | -3.54 | CDYL (chromodomain Y like) | protein interactions | 9425 | 87 | 33 | 19454 | 5460 |
CYBRD1,RPA3,H3C1,TNF,SLC15A1,DDX39A,MAP1LC3B,H2AX,MGARP,SMARCB1,FAM136A,EZH2,CTBP1,CBX3,H2BC1,HBB,CSNK2B,KLK6,H2AZ1,MAD2L1,APLNR,VIRMA,ESR2,NOP9,TTC9C,RBBP4,SNRNP40,HTRA1,LAMP2,MYC,BRD3,FAS,H2AC4 |
| 2.912e-02 | -3.54 | LRSAM1 (leucine rich repeat and sterile alpha motif containing 1) | protein interactions | 90678 | 87 | 33 | 19454 | 5460 |
FBXO22,TSG101,GSK3A,UBE2I,HRAS,RXRG,UBE2N,HSP90AA1,UBE2H,UBE2D1,UTP6,MYC,CUL3,USP2,ANKMY2,XAF1,CNOT6L,UBE2K,UBE2D3,YTHDF1,ERO1A,DR1,UBE3A,DDX5,EHD4,MGAT4B,PPME1,MTMR2,P3H1,DMAP1,GABARAPL2,UBE2W,PHF23 |
| 2.912e-02 | -3.54 | MIR141 (microRNA 141) | protein interactions | 406933 | 87 | 33 | 19454 | 5460 |
RARS1,HNRNPH3,P3H1,RBFOX2,STRBP,SF3A1,TRMT1L,G3BP2,MARS1,HNRNPK,HNRNPA0,TRA2B,HNRNPF,RTCB,ZC3H11A,SF3B1,HNRNPH2,HNRNPA2B1,IGF2BP1,DDX1,DDX23,NONO,HNRNPA1,APOBEC3B,KARS1,TENT2,FAM98A,HNRNPL,MATR3,SF3B4,MYEF2,EIF2AK2,SYNCRIP |
| 2.925e-02 | -3.53 | REEP1 (receptor accessory protein 1) | protein interactions | 65055 | 28 | 13 | 19454 | 5460 |
STX7,TMEM97,CSRP1,REEP3,REEP4,PLSCR1,TMEM100,CAV2,TMEM42,YWHAZ,ENDOD1,YWHAG,CAV3 |
| 2.925e-02 | -3.53 | LPIN1 (lipin 1) | protein interactions | 23175 | 28 | 13 | 19454 | 5460 |
PICK1,CDK6,EGLN3,DYRK1A,PRNP,PPARA,YWHAG,XPO1,CSNK1E,COP1,DCAF4,HSP90B1,FBXW11 |
| 2.925e-02 | -3.53 | OLR1 (oxidized low density lipoprotein receptor 1) | protein interactions | 4973 | 28 | 13 | 19454 | 5460 |
CDC42,RND2,RND3,RHOG,EZH2,RHOB,SYVN1,RAC2,RHOU,HRAS,KRAS,RHOJ,RHOH |
| 2.925e-02 | -3.53 | XCL1 (X-C motif chemokine ligand 1) | protein interactions | 6375 | 28 | 13 | 19454 | 5460 |
CXCL11,CXCL9,HSPA5,CXCL10,FSTL1,CXCL14,CCL21,CCL24,XCL1,CXCL12,CCL5,CCL11,CCL28 |
| 2.925e-02 | -3.53 | PACRG (parkin coregulated) | protein interactions | 135138 | 28 | 13 | 19454 | 5460 |
CCT2,HSP90AA1,CCT5,TP53,FBXO7,TUBA1A,TNF,HNRNPL,TCP1,TUBB,GPR37,CCT7,STUB1 |
| 2.925e-02 | -3.53 | MUTYH (mutY DNA glycosylase) | protein interactions | 4595 | 28 | 13 | 19454 | 5460 |
NME4,HUWE1,MSH6,APEX1,HRAS,SEC61B,PCNA,TDRD7,LMNA,TOPBP1,AGTRAP,CUL3,SMAD1 |
| 2.925e-02 | -3.53 | CHCHD2P9 (coiled-coil-helix-coiled-coil-helix domain containing 2 pseudogene 9) | protein interactions | 645345 | 28 | 13 | 19454 | 5460 |
OPTN,VDAC2,AURKAIP1,PRMT2,RPA2,G3BP1,TDP1,CHTOP,MEPCE,HEXIM1,CBL,SETD7,H1-1 |
| 2.925e-02 | -3.53 | ASNSD1 (asparagine synthetase domain containing 1) | protein interactions | 54529 | 28 | 13 | 19454 | 5460 |
PFDN6,NHERF1,RPAP2,POLR1D,PPP1CC,RAF1,WWP2,POLR2B,PTGES3,RUVBL1,RUVBL2,POLR3B,LDLR |
| 2.925e-02 | -3.53 | ZNF428 (zinc finger protein 428) | protein interactions | 126299 | 28 | 13 | 19454 | 5460 |
CSNK2A1,BAG3,MFAP1,CHAMP1,DMAP1,PIP4K2C,MACROH2A1,PARP2,BANF1,MAD2L2,GTF2I,HMGB1,S100A10 |
| 2.925e-02 | -3.53 | STRADB (STE20 related adaptor beta) | protein interactions | 55437 | 28 | 13 | 19454 | 5460 |
STK11,CCT7,CCT2,TRAF6,TCP1,DDX39A,CAB39,TIMM13,TIMM8A,CREB1,STUB1,CCT8,CCT5 |
| 2.925e-02 | -3.53 | NOPCHAP1 (NOP protein chaperone 1) | protein interactions | 121053 | 28 | 13 | 19454 | 5460 |
KPNA1,UBE2H,DNAJB6,KBTBD4,ZCCHC10,SPPL3,KRAS,NOP58,RUVBL1,KPNA2,EWSR1,RUVBL2,EMC2 |
| 2.925e-02 | -3.53 | Immt (inner membrane protein, mitochondrial) | protein interactions | 76614 | 28 | 13 | 19454 | 5460 |
MAT2A,AKR7A2,FBXL19,EXOC3,CCNF,BCL7B,RAN,GOSR1,PSMA5,DBR1,TICAM1,CD99L2,TNPO3 |
| 2.925e-02 | -3.53 | EIF2AK1 (eukaryotic translation initiation factor 2 alpha kinase 1) | protein interactions | 27102 | 28 | 13 | 19454 | 5460 |
STUB1,DELE1,CDK6,HSPA8,KDM1A,EIF2S1,HSP90AB1,CACYBP,MDM2,FASLG,H1-5,MFAP1,HSP90AA1 |
| 2.925e-02 | -3.53 | B3GALNT2 (beta-1,3-N-acetylgalactosaminyltransferase 2) | protein interactions | 148789 | 28 | 13 | 19454 | 5460 |
CUL3,TMBIM1,NUBP2,AMIGO1,KLF12,TAFAZZIN,HNRNPL,FBXW7,PRNP,EIF2B2,SFRP4,PLD3,OS9 |
| 2.925e-02 | -3.53 | ARAP2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2) | protein interactions | 116984 | 28 | 13 | 19454 | 5460 |
YWHAH,YWHAG,CDC42,SFN,YWHAB,YWHAZ,GJA1,INPPL1,HRAS,LIN7C,VIRMA,KRAS,ARF6 |
| 2.925e-02 | -3.53 | CLRN1 (clarin 1) | protein interactions | 7401 | 28 | 13 | 19454 | 5460 |
TMEM147,MFSD5,UNC50,TMEM50B,MGST3,CTXN3,NRM,FUT9,SEC22B,DRAM1,C2CD2L,ZDHHC15,TMEM31 |
| 2.925e-02 | -3.53 | CAPN12 (calpain 12) | protein interactions | 147968 | 28 | 13 | 19454 | 5460 |
CAPN2,KIF2A,RIOK2,PPIL4,RFC5,PTDSS1,SPATS2L,TCP1,MCMBP,MPP1,INA,CPLX3,ZBTB33 |
| 2.925e-02 | -3.53 | IL22RA1 (interleukin 22 receptor subunit alpha 1) | protein interactions | 58985 | 28 | 13 | 19454 | 5460 |
RETSAT,DCAKD,DHRS7,IL22,CYB5R1,DIPK1A,SMPD2,SLITRK5,PIGA,EPHX1,DHRS3,TMX2,HRAS |
| 2.925e-02 | -3.53 | CD28 (CD28 molecule) | protein interactions | 940 | 28 | 13 | 19454 | 5460 |
YWHAZ,PIK3CA,GRAP2,CD247,DUSP14,PIK3R1,PIK3R2,CD80,IL12A,CD86,ITK,CD4,PIK3CG |
| 2.925e-02 | -3.53 | Tipin (timeless interacting protein) | protein interactions | 66131 | 28 | 13 | 19454 | 5460 |
RPA2,GINS4,MCM3,SAP30BP,GINS3,PEG10,CHMP2B,PCMTD1,THRAP3,HMCES,MAGED2,YIF1A,RPA3 |
| 2.925e-02 | -3.53 | NQO2 (N-ribosyldihydronicotinamide:quinone dehydrogenase 2) | protein interactions | 4835 | 28 | 13 | 19454 | 5460 |
KRAS,HNRNPL,PRNP,EFHC1,ELMO2,IKBKB,COPS5,CRAT,GORASP2,SPG21,MYC,DDIT4L,MOV10 |
| 2.925e-02 | -3.53 | CDKN2AIPNL (CDKN2A interacting protein N-terminal like) | protein interactions | 91368 | 28 | 13 | 19454 | 5460 |
RBM3,RPL3,RAF1,MYC,NTAQ1,PLEKHA8,CCL3,CHAMP1,AGR2,CBL,KPNA1,PSRC1,ZNF574 |
| 2.925e-02 | -3.53 | RASAL3 (RAS protein activator like 3) | protein interactions | 64926 | 28 | 13 | 19454 | 5460 |
NTAQ1,MAP1LC3B,YWHAZ,BRD3,CDR2L,SNRPA,PICK1,MAP1LC3A,HNRNPK,RASD1,WASF3,RIGI,HOMER1 |
| 2.925e-02 | -3.53 | MICAL2 (microtubule associated monooxygenase, calponin and LIM domain containing 2) | protein interactions | 9645 | 28 | 13 | 19454 | 5460 |
HRAS,RAB1B,HNRNPL,COPE,TRIM54,ARHGAP15,VIRMA,JPH4,CIAO1,PGRMC1,MYC,MAP2K3,BRCA1 |
| 2.925e-02 | -3.53 | ZFAND5 (zinc finger AN1-type containing 5) | protein interactions | 7763 | 28 | 13 | 19454 | 5460 |
PSMA1,PSMD6,SMURF1,CCNF,UBE3A,SQSTM1,TRAF6,RAD23B,KBTBD4,TNFAIP3,PSMC4,CUL3,UBLCP1 |
| 2.925e-02 | -3.53 | interferon-mediated signaling pathway | biological process | GO:0140888 | 60 | 25 | 18204 | 5365 |
AZI2,IFNA10,IFNAR1,IRF7,JAK2,SIN3A,IFNB1,IFI27,TP53,IFNG,STAT1,RAF1,MAVS,IRF3,IFNA13,TANK,TBK1,IFNA2,IFNGR1,IFNK,IFIH1,STAT2,JAK1,MYD88,IRF1 |
| 2.925e-02 | -3.53 | regulation of glucose import | biological process | GO:0046324 | 60 | 25 | 18204 | 5365 |
RNASEL,NFE2L2,ADIPOQ,TNF,PEA15,MIR223,IGF1,OSBPL8,MIR143,MIR107,MEF2A,GSK3A,SLC1A2,TERT,PID1,CREBL2,AKT1,AKT2,PIK3R1,LEP,SELENOS,GRB10,ARPP19,SLC25A27,PTPN11 |
| 2.925e-02 | -3.53 | response to cadmium ion | biological process | GO:0046686 | 60 | 25 | 18204 | 5365 |
MT1E,CER1,NUDT1,DTYMK,MT1X,MT2A,PRNP,KIT,CDK1,HSPA8,MTF1,AKT1,CDKN1B,JUN,GCLC,OGG1,SOD2,MT3,MMP9,SUMO1,PCNA,TERT,MT1M,FOS,MT1A |
| 2.933e-02 | -3.53 | human chr11q21 | chromosome location | human chr11q21 | 45 | 16 | 26134 | 5823 |
MIR1304,MED17,SRSF8,ENDOD1,ANKRD49,IZUMO1R,JRKL,MIR1260B,SESN3,SMCO4,MTMR2,TAF1D,GPR83,FAM76B,CWC15,PIWIL4 |
| 2.938e-02 | -3.53 | negative regulation of cell cycle process | biological process | GO:0010948 | 291 | 101 | 18204 | 5365 |
TOPBP1,NOP53,BCL6,NUF2,FAM107A,SOX2,TRIM37,RINT1,TOM1L2,RPL26,HINFP,OVOL1,CRLF3,RPA2,FBXO31,SPC24,NAE1,BAZ1B,ACVR1,CCNF,BUB3,NEK2,DLG1,PSMG2,CCND1,CTDSP1,MACROH2A1,PRPF19,CDKN1A,PML,CDC5L,MAD2L1,CCL2,PTEN,MIR29C,NABP1,RB1,IK,MIR424,CRADD,PRMT2,ZNF655,MIR16-1,H2AX,CACNB4,DCUN1D3,CDK5RAP3,SMARCA5,CDK1,AURKAIP1,RAD1,CTDSP2,JADE1,PTPN11,KLF4,MIR10A,BTN2A2,TP53,CDK2AP2,ZNF207,DTL,MIR873,MDM2,MIR133B,GNB1L,MIR15A,CDC20,FZR1,VPS4A,TOM1L1,IER3,RGCC,BRCA1,GPNMB,MIR193A,CDKN1B,MDC1,KLHL22,PPP1R10,RPS27L,NBN,CDC73,CHMP4C,MIR503,UFL1,NDC80,TNKS,MIR137,RBBP8,FBXO7,MIR638,RAD21,MAD2L2,CHMP2A,EZH2,MIR29A,BABAM1,TPRA1,CDKN2D,MAD2L1BP,MIR195 |
| 2.941e-02 | -3.53 | Regulation of Telomerase | Pathway Interaction DB | telomerasepathway | 66 | 31 | 2226 | 782 |
SAP30,HSP90AA1,SAP18,AKT1,RBBP4,TERT,UBE3A,IL2,MAX,MYC,SMAD3,NFKB1,DKC1,FOS,PARP2,RBBP7,SP1,SIN3A,CCND1,CDKN1B,TNKS,IRF1,IFNG,NBN,JUN,SMG5,HNRNPC,MXD1,PTGES3,XRCC5,RAD1 |
| 2.943e-02 | -3.53 | MOB2 (MOB kinase activator 2) | protein interactions | 81532 | 84 | 32 | 19454 | 5460 |
RAB14,TRIM24,RETREG3,EIF4A3,ACTA2,CCDC90B,NAP1L5,MAGOH,UBE2H,MED4,PDF,EPHA2,ATG3,RACGAP1,DEPDC1B,NTAQ1,FRA10AC1,PIK3R1,RIGI,SFT2D2,STK38,NSFL1C,PFKFB2,VDAC1,UFL1,SCYL2,RHOBTB1,PPID,CDK1,STIM1,JUN,MYL12B |
| 2.943e-02 | -3.53 | SRF (serum response factor) | protein interactions | 6722 | 84 | 32 | 19454 | 5460 |
NKX3-1,CD63,RXRG,CREB1,PELP1,GTF2F1,UBE2I,HNRNPL,BARX2,SRC,ELK1,PYCARD,HMGA1,NFKB1,CREBBP,NFYA,CSNK2A1,ATG7,CIRBP,RIT1,SP1,FOS,PML,TRIP4,FHL3,TRIM63,HDAC3,GTF2I,KRAS,SSRP1,SRFBP1,ELK4 |
| 2.943e-02 | -3.53 | CTTNBP2 (cortactin binding protein 2) | protein interactions | 83992 | 48 | 20 | 19454 | 5460 |
CCT8,PPP2CB,CTTN,CTTNBP2,TNIK,STK26,TCP1,DYNLL1,ACTB,KRAS,VIRMA,RAD21,ATP6V1G1,CTTNBP2NL,CCT5,PPP2R1A,STK24,CCT2,USP15,PDCD10 |
| 2.943e-02 | -3.53 | ELOVL1 (ELOVL fatty acid elongase 1) | protein interactions | 64834 | 48 | 20 | 19454 | 5460 |
RAC2,SLC1A1,RAB5A,RPA3,TECR,RIGI,HSPA5,APEX1,RAB11B,CERS2,TAGLN2,LDHA,VDAC1,CDC42,SOX2,ANP32A,MOV10,TP53,RPA2,PSMD10 |
| 2.943e-02 | -3.53 | NAPB (NSF attachment protein beta) | protein interactions | 63908 | 48 | 20 | 19454 | 5460 |
APEX1,ALOX5AP,STX6,STX7,GPM6A,NAPG,SNAP23,STX5,SYT2,STX1A,HAX1,STX12,NAPA,SDCBP,STX16,VAMP5,BET1,PLEKHO1,SNAP29,SIGLEC5 |
| 2.943e-02 | -3.53 | PHPT1 (phosphohistidine phosphatase 1) | protein interactions | 29085 | 48 | 20 | 19454 | 5460 |
CDC42,GTF2E2,TBK1,TRAPPC4,DNAJB6,RAD23B,PPP1R16A,PLS3,RIMOC1,IGBP1,LRRC1,NUDT9,RAB1A,PSME1,ATXN1L,PRDX4,APEX1,SAR1B,GDPGP1,AASDHPPT |
| 2.943e-02 | -3.53 | CMTM7 (CKLF like MARVEL transmembrane domain containing 7) | protein interactions | 112616 | 48 | 20 | 19454 | 5460 |
ADTRP,GGT7,BSCL2,RETREG3,TMX2,HAS3,TCTA,ELOVL4,SSMEM1,DNAJC1,PSMD6,PIANP,CLSTN3,FAM174A,TMEM174,STX1A,TMEM31,LMNA,TMEM106C,AGER |
| 2.943e-02 | -3.53 | NR1I2 (nuclear receptor subfamily 1 group I member 2) | protein interactions | 8856 | 48 | 20 | 19454 | 5460 |
DNAJC7,POU1F1,DYRK2,HSP90AA1,FGR,CHMP1A,TADA3,TP53,NR1I2,PPIA,MDM2,SRC,RBBP7,RBCK1,PSMC5,TRIM21,EP300,UBE2I,RXRG,ATF3 |
| 2.943e-02 | -3.53 | NACC2 (NACC family member 2) | protein interactions | 138151 | 48 | 20 | 19454 | 5460 |
KLHL22,RFXANK,RPP21,HSPB8,EPS8,MTA3,DNAJB6,BORCS8,MTA2,FEM1A,NACC2,DCTN3,FOXP3,TFPT,AANAT,CIB3,TWIST2,RBBP4,HNRNPL,RBBP7 |
| 2.943e-02 | -3.53 | LDHAL6B (lactate dehydrogenase A like 6B) | protein interactions | 92483 | 48 | 20 | 19454 | 5460 |
ARF4,HSPA5,DNLZ,BCCIP,LDHA,SOCS4,PRMT5,RAB1A,ARF1,SOD1,SNIP1,MDH1,SORD,NHERF1,SUV39H1,PRMT6,CAPN1,RAB5C,HSH2D,TP53 |
| 2.943e-02 | -3.53 | Tnpo1 (transportin 1) | protein interactions | 238799 | 48 | 20 | 19454 | 5460 |
CCHCR1,ATP1A1,PDF,IVNS1ABP,YIPF5,ATP5MG,MRPL11,CCDC47,ATP5PB,ATP5PD,TGFB1I1,PYGB,SRPRB,ATXN10,SGF29,SEC61B,CHCHD6,FAM83B,RTKN,DNM2 |
| 2.943e-02 | -3.53 | ATL1 (atlastin GTPase 1) | protein interactions | 51062 | 48 | 20 | 19454 | 5460 |
HSD17B11,SYVN1,DERL1,RTN4,RAB9A,SEC61B,STUB1,PTPN1,TMT1A,TMPO,STX7,KRAS,SEC62,POLR1D,OTULINL,ST7,RPN1,STIM1,ESYT1,SSR1 |
| 2.951e-02 | -3.52 | alcohol biosynthetic process | biological process | GO:0046165 | 92 | 36 | 18204 | 5365 |
CYP27B1,SPHK2,NPC1L1,CYB5R3,CYP11B2,PCBD1,MOXD1,PTS,CYP27A1,SPR,CYP11B1,ACAA2,NUS1,FDFT1,CYP2R1,ACER3,DBH,SPTSSA,HMGCS1,G6PD,MSMO1,PCK2,CFTR,ISYNA1,PLPP6,SRD5A3,MVD,SC5D,LBR,INSIG2,LEP,NSDHL,LIPA,SPTSSB,IMPA2,IP6K1 |
| 2.954e-02 | -3.52 | DCP1A (decapping mRNA 1A) | protein interactions | 55802 | 156 | 55 | 19454 | 5460 |
ZYX,GARRE1,LSM14A,PABPC1,HNRNPA2B1,RIGI,DCP2,TBK1,YTHDF2,TNRC6C,TP53,HGS,GTPBP1,CRKL,TSG101,EGLN3,CNTROB,KCTD3,YWHAG,XPO1,YWHAH,CPEB1,EDC3,MOV10,CBL,YWHAB,SMAD4,TRAF6,LSM12,SMG5,NUBP2,RPA3,RCCD1,PML,EIF4E,LSM8,KDM1A,AGO1,DUSP18,RPA2,MAP2K1,GSK3A,PHF21A,TRIM24,TRMT6,CCNF,ESR2,MYC,RAB2A,CEP85,SFN,LSM14B,PNRC1,YWHAZ,RC3H2 |
| 2.954e-02 | -3.52 | PITRM1 (pitrilysin metallopeptidase 1) | protein interactions | 10531 | 156 | 55 | 19454 | 5460 |
ABHD10,IMMP2L,REXO2,CHCHD2,UFM1,ABCE1,SLC25A10,SOD2,ARPC3,PDHA1,NDUFS3,HOXB1,CFAP68,CACYBP,CHMP2A,PREP,GATD3,SNX17,HDHD3,COQ10B,DDX1,PPM1K,DKK1,NDUFV2,OGDHL,PYGB,NME4,HSCB,LSM12,PRDX6,SDHAF4,BOLA3,MAPKAPK3,SEPHS2,NUFIP2,MFAP1,PAK5,RPA2,KLF3,VAPB,DHRS4,FBXL19,MRPL12,NUDT3,COQ8B,SUCLG2,ROMO1,NDUFAF4,VIRMA,CCNF,SP1,HTRA2,MRPS16,ATP5F1A,CFL2 |
| 2.964e-02 | -3.52 | VPS29 (VPS29 retromer complex component) | protein interactions | 51699 | 137 | 49 | 19454 | 5460 |
KRAS,TTC4,TOLLIP,CAPZA1,VPS26B,EMC2,CAPZA2,COMMD8,SPG21,SNX2,DYNC1I2,SNX1,COMMD6,VPS26C,VAMP7,WDR12,SKIC8,ANKRD50,VPS26A,FRA10AC1,COMMD5,ATG7,TBC1D5,ADRB2,CMAS,RGS2,BAP1,PPM1G,RPA3,SQSTM1,COMMD2,MED23,RPA2,PPARG,ATP6V1C1,SEC22B,SHMT1,COMMD3,STAT1,PSMD6,SNX3,TSN,DYRK1A,LIG3,GTF2F1,COMMD9,CCDC22,SNX5,NIBAN2 |
| 2.964e-02 | -3.52 | FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial) | protein interactions | 10667 | 137 | 49 | 19454 | 5460 |
AGTRAP,H1-5,FGF13,GAMT,HSCB,UTP23,G3BP2,CUL3,GRB10,STK38L,TOMM40,RPL26,ZCRB1,RC3H2,SYP,H1-1,ENO1,RPS3,ZNF655,TRIM27,TRIM54,STAT5A,RPL19,H1-3,TRAF2,ISG15,ZNF526,TFCP2,LLPH,SPRY1,KCNF1,RPL31,YIF1A,KCTD17,HIGD1C,CHCHD2,H1-6,KRAS,STX11,MDFI,HNRNPA1,MRPL18,RPS2,PHB1,FAHD1,PRR3,RPS16,RPS10,SURF6 |
| 2.965e-02 | -3.52 | NMD3 (NMD3 ribosome export adaptor) | protein interactions | 51068 | 115 | 42 | 19454 | 5460 |
EP300,RHOU,GSTT2B,PRPS1,KRAS,SLC31A1,GFPT1,ARHGAP1,GCLC,LNX2,DPH5,BUD23,RAD23B,RNF181,RNF7,CDPF1,MID1IP1,MRTO4,PSPC1,LMBR1L,TRMT6,WIF1,DKC1,RHOJ,STAT1,RPS16,ZNF622,NOP58,UFD1,LDB1,XPO1,CSNK2A1,RFC5,CPEB1,HMGCS1,CUL3,WWP2,PDIA3,MYC,MAT2A,RIT1,AHSA1 |
| 2.965e-02 | -3.52 | GNS (glucosamine (N-acetyl)-6-sulfatase) | protein interactions | 2799 | 115 | 42 | 19454 | 5460 |
AHCYL1,RIGI,RBBP7,G3BP1,TTC4,HSPA8,RUVBL2,ABCE1,HSPD1,PRPF4,CAPN2,PRKCA,ACACA,CNDP2,LDHAL6B,TUBB4B,FKBP14,KIF2A,MVD,TP53,CAPN1,MYL12A,VIRMA,BCCIP,G6PD,DEK,PSMD4,RBBP4,DYNC1I2,RPS20,EFNA3,MIDEAS,TUBA1B,UBFD1,NAPA,YWHAB,PSMD1,ST13,ATG9A,NFKB1,CLPX,PSMD3 |
| 2.965e-02 | -3.52 | PLEKHA7 (pleckstrin homology domain containing A7) | protein interactions | 144100 | 115 | 42 | 19454 | 5460 |
INPP5E,CDC42,SIPA1L1,VPS33A,FGFR1,RDH12,AGAP1,RTKN,FAM53C,PICK1,TESK2,KRAS,B9D2,FBXW7,SRSF12,FLOT1,FAM110B,SFN,YWHAG,MAP3K21,YWHAH,PCBD1,CTNNB1,TIAM1,YWHAZ,RHOB,BICD2,CCHCR1,STK11,YWHAB,CAMSAP2,RAB35,EIF4E2,CTNNA1,GJA1,ZMAT5,ARF6,SPPL3,KCTD3,RHOH,ESR2,VIRMA |
| 2.967e-02 | -3.52 | RNA polymerase II transcribes snRNA genes | REACTOME pathways | R-HSA-6807505 | 73 | 31 | 10285 | 3229 |
GTF2A1,INTS12,SNAPC3,POLR2C,GTF2F1,POLR2I,CDK9,GTF2B,TAF11,SNAPC1,POLR2F,POLR2G,TAF9,GTF2A2,GTF2F2,POLR2D,POLR2L,NABP1,GTF2E2,RPRD1B,PHAX,GTF2E1,CDK7,SP1,RPRD1A,SNAPC5,RPAP2,SNAPC2,INTS10,POLR2B,NCBP2 |
| 2.968e-02 | -3.52 | CD28 co-stimulation | REACTOME pathways | R-HSA-389356 | 33 | 16 | 10285 | 3229 |
GRAP2,AKT2,CD86,PIK3CA,YES1,AKT1,AKT3,CD28,MAP3K14,PIK3R2,PIK3R1,SRC,PIK3R3,PAK2,CDC42,CD80 |
| 2.972e-02 | -3.52 | ZNF620 (zinc finger protein 620) | protein interactions | 253639 | 81 | 31 | 19454 | 5460 |
CBX5,CIB3,KCTD9,EIF4A2,MAGOHB,TSR2,GYS1,FBLN5,CDPF1,CINP,EEF2KMT,CCHCR1,GAS8,CUL3,PIK3R3,CDKN2D,ZNF24,ATG9A,RERE,CDCA7L,DGCR6L,MYOZ3,BOLA2B,ZBTB16,OAZ3,SNAPC3,TRIM10,SART3,MFAP1,METTL21A,LMO3 |
| 2.972e-02 | -3.52 | DNAJC5B (DnaJ heat shock protein family (Hsp40) member C5 beta) | protein interactions | 85479 | 81 | 31 | 19454 | 5460 |
OXSR1,LEMD3,TFCP2,SLC12A2,ALG11,MARCKSL1,SLC6A8,ZDHHC17,STX7,RPS27A,RFC3,FTSJ1,PIK3R2,BAG2,SNAP23,DLG1,EPHA2,DNAJC7,PPFIBP1,DEPDC1B,ST13,VAMP7,FERMT2,CAV1,YES1,SLC30A7,FAM83B,CDCA3,STUB1,WDR6,SCAMP2 |
| 2.972e-02 | -3.52 | FADS1 (fatty acid desaturase 1) | protein interactions | 3992 | 81 | 31 | 19454 | 5460 |
PLD3,RNF181,MAP1LC3B,RND2,CDC42,PAAF1,CD80,GRPR,TOLLIP,PSEN1,SLC5A6,CXCR4,RHOU,TSPAN15,TACR1,BSCL2,EIF3G,CCDC22,VMP1,MYC,GPR17,FAM20C,TAX1BP1,RHOH,RHOJ,SLC7A8,OPRL1,KCNA2,LMBR1L,CD63,RAC2 |
| 2.972e-02 | -3.52 | PEX6 (peroxisomal biogenesis factor 6) | protein interactions | 5190 | 81 | 31 | 19454 | 5460 |
PEX3,FIS1,KLK5,MSMB,ATG7,FAM174A,MARCHF5,CUL3,EMILIN1,RAMP3,TUBB,OVGP1,PPM1M,OLFM2,SMAD3,S100A6,PSMC3,CTLA4,MGARP,KBTBD4,RPL27A,RPS14,TOP3B,PEX26,PXMP2,CERS2,THBS3,AKAP1,PSME1,RCCD1,OSTM1 |
| 2.972e-02 | -3.52 | HEXIM2 (HEXIM P-TEFb complex subunit 2) | protein interactions | 124790 | 81 | 31 | 19454 | 5460 |
CDK9,CACNB2,HNRNPL,ZNF655,HEXIM2,CSNK2B,AP2M1,SURF2,ID1,TADA3,SNRNP70,FERD3L,GAS8,CSNK2A1,XPO1,RIOX2,KLHL9,ZNF250,SPRED1,AHCYL1,MEPCE,PSMA1,TNFAIP1,EGFL7,PICK1,SPRY1,HEXIM1,SDCBP,DDX39A,FAM161A,RAF1 |
| 2.972e-02 | -3.52 | HAVCR2 (hepatitis A virus cellular receptor 2) | protein interactions | 84868 | 81 | 31 | 19454 | 5460 |
PIK3R3,CNTNAP1,PKP4,PIK3R1,RHOBTB3,IQSEC1,MAP3K21,PIGA,AGPAT1,SNX17,MGST3,WDR44,PTP4A3,TCAF2,LGR4,SEC22A,ZMYM6,PIK3CA,CERK,CNKSR3,BMPR1A,JAK1,ERG28,SLC20A2,PIK3R2,IL1RAP,TSPAN7,GOLGA7,RIGI,GSKIP,CLDND1 |
| 2.974e-02 | -3.52 | - | gene3d domains | 2.40.50.100 | 17 | 9 | 14470 | 4137 |
ATP6V1A,DLAT,PC,EXOSC3,DLST,DBT,ABITRAM,EXOSC1,ACACA |
| 2.975e-02 | -3.51 | RRM_dom | interpro domains | IPR000504 | 215 | 76 | 18521 | 5414 |
RBM3,RBMX2,CPEB1,RBM34,EWSR1,EIF4B,RBM38,SRSF8,SART3,HNRNPF,PABPC5,RBFOX3,RBFOX2,SRSF2,NONO,TRA2B,RBM12,RDM1,G3BP1,HNRNPA0,PPIL4,RALYL,HNRNPC,RBM42,NCBP2,ALYREF,RBM5,POLDIP3,RBMS2,RBM27,SRSF12,BOLL,G3BP2,SRSF7,HNRNPA1,HNRNPDL,HNRNPH3,PABPC1,IGF2BP1,RBM7,TNRC6C,PSPC1,SNRPA,HNRNPL,GRSF1,HNRNPD,SRSF1,SNRNP70,RBM15B,TRA2A,SRSF10,EIF4H,MYEF2,ZCRB1,ELAVL4,HNRNPH2,MATR3,RBM22,CELF6,HNRNPAB,RBM41,SF3B6,HNRNPA2B1,SRSF4,CSTF2T,TIA1,CIRBP,EIF3G,RBM18,SYNCRIP,UHMK1,SF3B4,ELAVL2,RBM17,RBM23,SNRPB2 |
| 2.975e-02 | -3.51 | response to fibroblast growth factor | biological process | GO:0071774 | 95 | 37 | 18204 | 5365 |
FLRT3,RAB14,NDNF,FGF22,FGF7,FGFR1,GCLC,FGF16,EXT1,CRKL,SHOC2,FGFBP1,PTPN11,FRS3,NOG,MIR149,FLRT2,CXCL13,DSTYK,FGF23,MIR339,FGF1,CCL2,FGF17,PAX6,CXCL8,CCL5,FGF3,ELK1,KCNC1,IER2,SFRP1,NDST1,HYAL2,NPR2,FGF10,CTNNB1 |
| 2.976e-02 | -3.51 | human chr14q24.3 | chromosome location | human chr14q24.3 | 78 | 25 | 26134 | 5823 |
EIF2B2,TGFB3,ISCA2,BATF,CIPC,POMT2,DNAL1,NPC2,ACOT6,ERG28,FOS,AHSA1,NGB,NEK9,IRF2BPL,DLST,FCF1,MIDEAS,ADCK1,VIPAS39,VASH1,VRTN,PNMA1,MLH3,AREL1 |
| 2.979e-02 | -3.51 | Proteoglycans in cancer | KEGG pathways | hsa05205 | 203 | 83 | 7161 | 2463 |
CAMK2G,WNT10B,HSPB2,PIK3R3,TLR2,CAV2,IGF1,TWIST2,PIK3CA,ROCK1,PPP1R12A,SOS2,TNF,SDC2,CBL,WNT2,AKT2,MIR10A,ITGB5,WNT7A,CDKN1A,ITGA2,PRKCB,VAV2,GAB1,TIAM1,FZD4,IL12B,PTPN11,MDM2,DDX5,PPP1CB,FASLG,CAV1,CCND1,MMP9,CAV3,TLR4,PIK3R1,KRAS,HBEGF,PIK3R2,CDC42,AKT1,MRAS,ACTB,FGFR1,EIF4B,PRKCA,RRAS2,SMAD2,CD63,GPC1,SDC4,ELK1,MAP2K1,CTNNB1,MIR21,AKT3,MYC,MSN,LUM,FAS,ROCK2,SRC,HRAS,FZD6,IGF1R,VEGFA,DROSHA,HCLS1,PRKACB,RAF1,ITGAV,TGFB2,MIR10B,TIMP3,PPP1CC,CTTN,PDCD4,TP53,MET,FZD3 |
| 2.979e-02 | -3.51 | Proteoglycans in cancer | KEGG pathways | ko05205 | 203 | 83 | 7161 | 2463 |
MYC,MSN,LUM,FAS,AKT3,MIR21,ELK1,CTNNB1,MAP2K1,GPC1,CD63,SDC4,SMAD2,PRKCA,RRAS2,EIF4B,FGFR1,MRAS,ACTB,MET,FZD3,PDCD4,CTTN,TP53,TIMP3,MIR10B,PPP1CC,TGFB2,ITGAV,HCLS1,DROSHA,RAF1,PRKACB,VEGFA,IGF1R,FZD6,SRC,HRAS,ROCK2,PRKCB,WNT7A,CDKN1A,ITGB5,ITGA2,AKT2,MIR10A,SDC2,WNT2,CBL,PPP1R12A,ROCK1,PIK3CA,TNF,SOS2,IGF1,TWIST2,CAMK2G,WNT10B,CAV2,HSPB2,TLR2,PIK3R3,AKT1,HBEGF,CDC42,PIK3R2,KRAS,PIK3R1,CCND1,MMP9,CAV1,TLR4,CAV3,MDM2,PTPN11,FASLG,PPP1CB,DDX5,FZD4,IL12B,GAB1,TIAM1,VAV2 |
| 2.981e-02 | -3.51 | leukocyte activation involved in immune response | biological process | GO:0002366 | 201 | 72 | 18204 | 5365 |
MYD88,CBL,CD1C,KIT,JAK1,SNAP23,IFNK,PTGER4,IFNA2,PSEN1,NBN,LAT2,LILRA2,IFI35,IRF4,IL2,PDP2,MSH6,RC3H2,NMI,GAPT,VAMP2,IFNB1,SOCS3,TICAM1,TYROBP,PTGDS,ST3GAL1,RAB27A,LCP1,EXOSC3,SWAP70,CHGA,IRF8,CPLX2,PRKCE,FOXP3,VAMP8,BCL6,HSPD1,LILRB1,HMGB1,SYK,CCL3,PIK3CG,PYCARD,TNFSF18,CD40LG,BATF,TLR4,CCR6,IFNA13,STAT6,FCGR2B,RNF8,FGL2,ICAM1,FCER1G,KARS1,IFNG,TP53,IL12B,FOXP1,NOTCH2,ITM2A,TNF,IFNA10,VAMP7,IL21,CX3CR1,MRGPRX2,IL6 |
| 2.987e-02 | -3.51 | KANK2 (KN motif and ankyrin repeat domains 2) | protein interactions | 25959 | 279 | 93 | 19454 | 5460 |
ZNHIT1,THAP1,EXOSC8,CAMK2G,RBCK1,PSEN1,GARRE1,EGFL8,SSX2IP,CSNK2A1,EDC3,CDC5L,AIFM1,PDE9A,RAC2,P3H1,TFIP11,TMOD1,CHIC2,DDIT4L,FAM161A,PRMT2,FBXW7,OIP5,EIF4E,HSPB2,CHCHD4,SERTAD3,MCCD1,GMNN,PCBD1,CEP70,TRIM54,TRAF1,SRPK2,DYRK1A,CINP,GSK3A,MOB3C,TOP3B,CFAP68,TRAF2,SNAPIN,G3BP1,FLOT1,PAX6,ZYX,FHL3,ARL14EP,LBX1,MED4,NDC80,HSPB8,XPO1,PPFIBP1,TRIM35,RHOH,CYTH4,CNTROB,PRPF18,HOMER3,PSMB4,THAP6,NCOA5,ZBTB42,PRR5L,GKAP1,PPP1CB,LMO4,BORCS6,LMO3,SRSF2,MYOZ3,HAND2,WASF3,TIFA,PELI3,RHOB,YWHAZ,PSMD14,PFDN6,LMO2,GRB10,RAB11A,PRPF31,TAX1BP1,DYNLL1,CHCHD3,ESR2,VMAC,SCNM1,PRMT5,ZMAT2 |
| 2.987e-02 | -3.51 | response to glucose | biological process | GO:0009749 | 149 | 55 | 18204 | 5365 |
TXNIP,EGR1,PAX6,SIN3A,VAMP2,EIF2B2,MIRLET7G,TRA2B,CMA1,MIR16-1,PRKCB,FKBP1B,SMAD2,SESN2,CDKN1B,MIR320A,XBP1,PCK2,EIF2B5,NPTX1,MIR146A,MIR221,CCDC186,OPRK1,CYP7A1,SLC29A1,SMAD3,ICAM1,RAF1,SARM1,UCP2,ACVR1C,ADIPOQ,KCNB1,PIK3CA,MIR15A,GPX1,EIF2B3,CLTRN,IGF1R,GLUL,GPAM,TWNK,RAB11B,PPP3CA,HNF1B,RMI1,KCNJ11,GCLC,SMAD4,SELENOT,PFKFB2,SELENOS,AGER,ZBED3 |
| 2.989e-02 | -3.51 | BLOC1S1 (biogenesis of lysosomal organelles complex 1 subunit 1) | protein interactions | 2647 | 51 | 21 | 19454 | 5460 |
KXD1,SNAPC5,LAMTOR2,SNAPIN,FBXO44,BLOC1S3,BORCS6,BCAS4,PTP4A2,LAMTOR1,BLOC1S5,BORCS5,SCLT1,BORCS8,HGS,PELP1,BLOC1S2,PTEN,FZR1,PTN,BORCS7 |
| 2.989e-02 | -3.51 | ALDH5A1 (aldehyde dehydrogenase 5 family member A1) | protein interactions | 7915 | 51 | 21 | 19454 | 5460 |
MRPL50,VDAC1,UMPS,PRNP,MRPL23,HSCB,IRAK4,METAP2,SSBP1,PRKD3,RPA3,SRP54,HSPA8,BRCA1,RPA2,KLF3,UBE2M,SOD2,ACO2,RPE,TOMM40 |
| 2.993e-02 | -3.51 | protease binding | molecular function | GO:0002020 | 138 | 52 | 18094 | 5411 |
VWF,TNF,ATP5F1A,FLOT1,FURIN,ADRM1,SERPINA1,CDK5R1,DERL1,SLC6A3,CSTB,SERPINB9,COL1A2,SERPINA5,SUMO1,SERPINB6,DPP4,TIMP1,TRIP4,CRADD,BCL10,BFAR,SELENOS,PTEN,RNF139,KIT,SRI,NTRK2,CST3,TWNK,TP53,PLG,TNFAIP3,PYCARD,OS9,PRNP,COL3A1,TIMP4,MIF,FAM20C,SEMG2,CSTA,SERPINC1,SELL,SART3,TIMP3,SYVN1,SPATA2,LDLR,ITGAV,STIM1,CD28 |
| 2.998e-02 | -3.51 | NSUN4 (NOP2/Sun RNA methyltransferase 4) | protein interactions | 387338 | 78 | 30 | 19454 | 5460 |
RPL18,RPLP0,VAPB,RPL15,MND1,AURKAIP1,CHST7,CA10,SRSF4,RPL28,FBXW7,NPM3,SQSTM1,EWSR1,AMACR,NKAPD1,HSPD1,SLC25A10,FTSJ3,TAFAZZIN,YWHAH,ESR2,SURF6,LYAR,FAHD1,PRKRA,SSMEM1,FBXO32,MYEF2,SRP14 |
| 2.998e-02 | -3.51 | GADD45G (growth arrest and DNA damage inducible gamma) | protein interactions | 10912 | 78 | 30 | 19454 | 5460 |
CCNB1,HP,GADD45B,EIF3G,TSNAX,RRP7A,CEP57L1,ZNF664,RAN,PHAX,FAM156A,DDAH2,LRIF1,DDIT4L,CDKN1A,EEF1A1,PPARA,PPARG,CDK1,EZH2,MED31,SMARCB1,SH3GLB2,SH3GLB1,GADD45A,BLOC1S2,PCNA,EEF1G,PTN,ENKD1 |
| 2.998e-02 | -3.51 | PMS2 (PMS1 homolog 2, mismatch repair system component) | protein interactions | 5395 | 78 | 30 | 19454 | 5460 |
PML,RUVBL2,PCNA,GALNT12,TRMO,REXO2,KPNA2,RUVBL1,PSMC1,POLR1H,RFC2,MSH6,ANP32B,TP53,LMNA,PARD6A,PSMC3,AIFM1,ZNF189,PPP2CB,TRIM29,PRNP,VPS26C,PSD2,SFRP4,AKT1,XPO1,MCM3,BRCA1,TOPBP1 |
| 2.998e-02 | -3.51 | TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2) | protein interactions | 26115 | 78 | 30 | 19454 | 5460 |
CDC42,SIPA1L1,SPG21,ATG16L1,INPP5E,TOP3B,AGAP1,PAK5,FHL3,TRIM11,ZYX,SNIP1,RTKN,RIGI,YWHAG,XPO1,BRAP,YWHAH,CTNNB1,PPP1CC,TAX1BP3,SFN,YWHAB,MAPRE1,YWHAZ,TYMS,EIF4E2,CDC5L,VIRMA,KCTD3 |
| 2.998e-02 | -3.51 | CABIN1 (calcineurin binding protein 1) | protein interactions | 23523 | 78 | 30 | 19454 | 5460 |
SMARCB1,CDAN1,SPRR1B,TOP3B,PAX6,MEF2A,ASF1A,H3C1,HIRA,RPA3,PPP3CA,H1-1,UBE2H,BRCA1,CSTA,SUV39H1,MEF2B,ZCCHC10,HNF1B,HMGA1,ESR2,VIRMA,IFI6,GRM1,RBBP4,CALML5,CTTN,UBN1,FABP5,SIN3A |
| 2.998e-02 | -3.51 | CSTPP1 (centriolar satellite-associated tubulin polyglutamylase complex regulator 1) | protein interactions | 79096 | 78 | 30 | 19454 | 5460 |
TUBG1,TPGS2,DCAF4,CSK,ENY2,CDC16,CIAO1,NDC80,PRKACB,NDN,RPL8,RMDN3,PHF21A,PICALM,NICN1,TBC1D19,ATG16L1,PNMA5,SEC62,KIF2A,DET1,KDM1A,PSMA1,TRIM37,GCA,PHF1,RAB29,SPECC1L,ZC3H7A,UBE3A |
| 2.998e-02 | -3.51 | PPP1R15B (protein phosphatase 1 regulatory subunit 15B) | protein interactions | 84919 | 78 | 30 | 19454 | 5460 |
TACR3,RAD21,FKBP8,KRAS,LRP3,DERL1,AKAP1,EXD2,SIGLECL1,SEC62,DNAJC25,OTULINL,PPP1CB,TULP3,TOP3B,MTCH2,VTI1B,MARCHF4,DNAJC1,HSD17B11,SEC61B,KCNA2,CHRM4,CHRM5,RIT1,FAS,FBXW11,TRIM23,UFD1,PPP1CC |
| 3.007e-02 | -3.50 | Bone Morphogenic Protein (BMP) Signalling and Regulation | WikiPathways | WP1425 | 12 | 8 | 5310 | 1910 |
BMPR1B,SMAD1,BMPR2,BMPR1A,SMAD4,NOG,TOB2,SMURF1 |
| 3.013e-02 | -3.50 | regulation of transcription by RNA polymerase I | biological process | GO:0006356 | 46 | 20 | 18204 | 5365 |
ZMPSTE24,MAF1,LYAR,RASL11A,POLR2L,UTP15,SMARCA5,MACROH2A1,SF3B1,BAZ1B,SMARCB1,SIRT7,MACROH2A2,NOP53,PIH1D1,DEK,DEDD,MARS1,ATF4,CREBBP |
| 3.013e-02 | -3.50 | regulation of T cell receptor signaling pathway | biological process | GO:0050856 | 46 | 20 | 18204 | 5365 |
RAB29,CCR7,BTN2A2,TESPA1,LIPA,PRNP,CD81,RPS3,CD226,LILRB4,NECTIN2,THY1,PTPN22,LGALS3,DUSP22,SH2D1A,DUSP3,BCL10,SLA2,ELF1 |
| 3.013e-02 | -3.50 | negative regulation of peptide hormone secretion | biological process | GO:0090278 | 46 | 20 | 18204 | 5365 |
CARTPT,JAGN1,HADH,GNAO1,LEP,CCN3,FKBP1B,CRHBP,PTPN11,CHGA,SFRP1,NDUFAF2,KCNJ11,ENY2,GHRL,KCNB1,PPP3CA,UCP2,GNAZ,ACVR1C |
| 3.013e-02 | -3.50 | leukocyte apoptotic process | biological process | GO:0071887 | 46 | 20 | 18204 | 5365 |
IL2RA,BCL2L1,LMBR1L,DFFA,AKT1,BCL10,FAS,TP53,LIPA,BAX,GPAM,TRAF3IP2,KDELR1,BAK1,PDCD1,IL6,IRF3,PLEKHO2,CRKL,FASLG |
| 3.014e-02 | -3.50 | purine nucleotide catabolic process | biological process | GO:0006195 | 101 | 39 | 18204 | 5365 |
FKRP,PFKFB2,BPGM,ACAT1,ENO2,PDE4B,NUDT7,PDE7A,PGK1,LIPA,OGDHL,ENO1,HTR2A,ENTPD4,PGAM1,PDE9A,PNP,PDE8A,LDHA,NUDT12,NUDT3,SAMHD1,IER3,NUDT19,PGM1,PDE2A,DNPH1,NUDT9,GAPDH,NUDT18,NUDT16,SUCLG2,PDE1A,SARM1,FITM2,UCP2,NUDT4,HINT1,NT5C2 |
| 3.018e-02 | -3.50 | occipital_lobe | COSMIC cancer mutations | occipital_lobe | 33 | 15 | 16828 | 4835 |
ZNF821,KRAS,MSH6,IDH1,GNAQ,TP53,GNA11,CTNNB1,IDH2,FBXW7,NF2,EZH2,HDHD3,EFCAB7,PTEN |
| 3.019e-02 | -3.50 | CEP170P1 (centrosomal protein 170 pseudogene 1) | protein interactions | 645455 | 112 | 41 | 19454 | 5460 |
CCAR2,DAPK3,VTI1B,CD99L2,CSTF3,POLR2B,RAN,PRCC,FBXO31,CPSF1,COPS2,TNKS,ASB7,KXD1,RBM15B,CPSF2,PRKACB,SMARCE1,ZNF668,OIP5,TICAM1,VAMP8,HSPD1,STX8,SHISA2,BAG2,P4HA2,MAP2K1,RPRD1B,P3H1,KLHL12,SUPT5H,HEXA,UBL4A,DSTYK,LMO3,RALYL,LMO4,CSTF2T,SNAPIN,SOX2 |
| 3.021e-02 | -3.50 | SPTLC2 (serine palmitoyltransferase long chain base subunit 2) | protein interactions | 9517 | 75 | 29 | 19454 | 5460 |
FAM241A,LRRTM1,CUL3,PTPN5,FAM20C,TSPAN10,MYC,RIT1,BRCA1,ESYT1,SPINT2,CCNF,LMBR1L,VIRMA,FZR1,CFTR,MYCT1,OTULINL,FAXC,PTAR1,RPA2,DERL1,HSPA8,LPAR2,BSCL2,RPA3,BCL6,LPAR1,HSCB |
| 3.021e-02 | -3.50 | SHCBP1 (SHC binding and spindle associated 1) | protein interactions | 79801 | 75 | 29 | 19454 | 5460 |
SOX2,DHX38,ATG16L1,WTAP,PRKCA,ZNF574,RPA2,TUBB4B,CBX3,RING1,HSPA8,PRKCB,SSRP1,HSPA5,H3C1,RACGAP1,WDR11,YWHAH,YWHAG,SFN,SMARCA5,MYC,YWHAB,YWHAZ,SHC1,RCHY1,VIRMA,RBBP4,PRNP |
| 3.021e-02 | -3.50 | MIR429 (microRNA 429) | protein interactions | 554210 | 75 | 29 | 19454 | 5460 |
TRA2A,NONO,HNRNPA1,KARS1,APOBEC3B,IGF2BP1,DDX1,DDX23,SF3B4,EIF2AK2,MYEF2,SYNCRIP,CDC5L,MATR3,HNRNPL,STRBP,RBFOX2,HNRNPH3,RARS1,RTCB,SF3B1,HNRNPH2,HNRNPA2B1,G3BP2,MARS1,HNRNPK,HNRNPF,TRA2B,HNRNPA0 |
| 3.021e-02 | -3.50 | PDE3A (phosphodiesterase 3A) | protein interactions | 5139 | 75 | 29 | 19454 | 5460 |
GMPPB,AKT1,FBXO7,RHOG,DOLK,TMEM11,HSPB1,ARL10,AIP,RAC2,GANAB,SLC30A7,TAX1BP1,REEP4,RANBP6,CAV1,RMND1,VIRMA,B3GNT2,CDC42,RND2,JUP,RPA2,MOB3C,CAV2,RPA3,FBXO11,GOSR1,HSPA5 |
| 3.021e-02 | -3.50 | MEF2A (myocyte enhancer factor 2A) | protein interactions | 4205 | 75 | 29 | 19454 | 5460 |
SMAD2,SMAD4,AR,MEF2B,XPO1,HNRNPA1,PTPN5,APEX1,HNRNPL,UBE2I,VGLL4,GNG12,H2BC1,GABARAPL2,JUN,SOX2,ACTN4,SUMO1,MEF2A,PHB2,HDAC3,TSR3,EP300,CDK5,HDAC5,MAPKAPK3,ATF3,MEF2C,HIRA |
| 3.021e-02 | -3.50 | CDC25C (cell division cycle 25C) | protein interactions | 995 | 153 | 54 | 19454 | 5460 |
STARD13,PNMA2,PPP2R1A,TP53,KIF1C,RPS27A,SRSF12,AHCYL1,S100A10,MYO1B,PCNA,CDK5,TESK2,FHL3,HSPD1,CAMSAP2,YWHAB,TIAM1,SHC1,YWHAH,YWHAG,CSNK2A1,GLO1,VPS26A,MDM2,KCTD3,MIF,HRAS,EIF4E2,HECTD1,CDK1,SLC12A2,SIPA1L1,LMO3,CCNA2,INPP5E,SUFU,NFYB,GRPEL1,RER1,EP300,RTKN,HSP90AA1,SP1,ILK,BRCA1,YWHAZ,MAP3K21,LMO2,NFYA,SFN,CCNB1,TBCCD1,CCNF |
| 3.022e-02 | -3.50 | ANKS6 (ankyrin repeat and sterile alpha motif domain containing 6) | protein interactions | 203286 | 54 | 22 | 19454 | 5460 |
BET1,AGTRAP,TIMM10,TOP3B,TIMM29,NEK7,ARL15,ATAD1,KRAS,UFL1,TMEM60,RIGI,STX7,MARCHF5,VEZT,ATG9A,DDRGK1,XPO1,LAMTOR1,DDX1,HRAS,CETN3 |
| 3.022e-02 | -3.50 | FHIP2A (FHF complex subunit HOOK interacting protein 2A) | protein interactions | 57700 | 54 | 22 | 19454 | 5460 |
GOLGA5,MAPRE1,KLC2,SCFD1,GPR17,SEC22B,GOSR2,BET1,ATG16L1,CSK,WDR11,RAB6A,SLC30A5,XPO1,GOSR1,VAMP7,FAM91A1,STX5,BET1L,EFNB1,VLDLR,SLC30A7 |
| 3.022e-02 | -3.50 | SEC24D (SEC24 homolog D, COPII coat complex component) | protein interactions | 9871 | 54 | 22 | 19454 | 5460 |
PICALM,TP53,LMO4,GTF2E2,CD2AP,RIGI,SAR1B,NRBF2,ARFIP1,EWSR1,IL17F,PLEKHO1,SEC13,WWP2,MYC,CARS1,XPO1,TMA16,TAX1BP1,VIRMA,SEC23A,SF3B4 |
| 3.022e-02 | -3.50 | NOS1 (nitric oxide synthase 1) | protein interactions | 4842 | 54 | 22 | 19454 | 5460 |
HSP90AA1,VAC14,DCAF11,PRKCA,NOS1AP,SNTA1,CAMK1,CTBP1,SOX2,CAV3,OS9,PRNP,DYNLL1,ADRB2,RASD1,ADRB1,CSNK2B,ADRA1A,DLG4,ATP2B4,NOSIP,STUB1 |
| 3.025e-02 | -3.50 | CD40/CD40L signaling | Pathway Interaction DB | cd40_pathway | 30 | 16 | 2226 | 782 |
TRAF2,JUN,MAP3K14,NFKBIA,AKT1,IL4,CD40,TRAF6,CD40LG,MAPK10,TRAF1,STAT5A,MYC,BIRC2,TNFAIP3,NFKB1 |
| 3.026e-02 | -3.50 | FGFBP1 (fibroblast growth factor binding protein 1) | protein interactions | 9982 | 253 | 85 | 19454 | 5460 |
RPS14,TFB1M,RPL26L1,ZNF770,APOBEC3C,SF3B1,CCDC106,BRIX1,AATF,UTP23,DGCR8,RPS15,GPC1,STAU1,RPL4,NOP53,RPL26,SMARCA5,RPF2,NOP16,RPS5,H1-1,CHTOP,FTSJ3,RBMX2,PRKRA,FGFBP1,RPL37A,ZNF22,PELP1,RPS3,ZNF189,RSL24D1,VIRMA,SRPK2,PRRC2A,RPP25L,RPF1,RPL7L1,TAF1D,MAK16,ZNF397,RPS7,FCF1,TRMT1L,STRBP,SRP72,GLE1,RBM34,RPL3,NKRF,ZNF787,RPS13,RPS27A,GTF3C3,RPS4X,SSRP1,RPL17,H1-6,PAK1IP1,IMP4,NOC4L,FGF1,NGDN,DDX50,CMSS1,SPATS2L,RPS2,RSBN1L,CDK12,NOL12,ZCCHC9,DCAF5,H2BC17,MPHOSPH10,HP1BP3,PWP2,RPL8,KRR1,RPL32,DKC1,SURF6,CDC5L,RPS10,TOP1 |
| 3.030e-02 | -3.50 | PC (pyruvate carboxylase) | protein interactions | 5091 | 185 | 64 | 19454 | 5460 |
RPN1,DISC1,DTWD2,ILF2,TOP3B,RAF1,B3GNT2,KBTBD4,TP53,PPP2R1A,FOXJ3,HUWE1,ARF4,SAR1B,TMEM87A,LSM14A,AGR2,HSPB1,WWP2,FAM174A,MALSU1,TMPO,G6PD,UBE2N,ARL10,FBXO32,YBEY,FAHD1,TES,ARL4D,RPA2,SLC25A3,ACACA,SSBP2,TSHR,DET1,CDK7,KDM1A,FBXW7,ADRB2,RPA3,DVL2,AMACR,PML,HSPA8,THBS3,RNF113A,SPCS3,DCAF4,TRIM23,KLK5,ATP1A1,MYC,CSK,TUFM,PCCB,NDN,CYP27A1,DYNLL1,ESR2,CCNF,UQCRC2,PTEN,PHF21A |
| 3.031e-02 | -3.50 | JAK-STAT signaling | KEGG pathways | hsa_M00684 | 19 | 11 | 7161 | 2463 |
SOCS2,SOCS4,CISH,JAK1,SOCS5,STAT2,STAT1,SOCS3,JAK2,STAT5A,STAT6 |
| 3.031e-02 | -3.50 | JAK-STAT signaling | KEGG pathways | M00684 | 19 | 11 | 7161 | 2463 |
SOCS2,SOCS4,JAK1,CISH,SOCS5,STAT1,STAT2,SOCS3,STAT5A,JAK2,STAT6 |
| 3.039e-02 | -3.49 | SEMG2 (semenogelin 2) | protein interactions | 6407 | 72 | 28 | 19454 | 5460 |
NXPH3,LSM14B,MSMB,FOXP3,DPEP1,MAT2B,KLK3,STX6,LYZL6,FTH1,CFTR,SOX2,NEK2,SERPINA5,NUPR1,PRKCA,FKBP14,HBB,TPPP,HSPA8,HACD1,HAPSTR1,TRIM10,LYG2,AZGP1,RDH11,POLL,PIK3R2 |
| 3.039e-02 | -3.49 | CETN3 (centrin 3) | protein interactions | 1070 | 72 | 28 | 19454 | 5460 |
CCDC127,STT3A,TCAP,LDB2,ATP5F1B,CETN2,LRIF1,CUL3,MYC,PNOC,ENY2,ATP5F1A,AGR2,IGFBP4,HSPB1,SMG8,BCKDK,HADHA,RBCK1,FTL,DDI1,TANK,DCAF12L2,TNNI1,DMAP1,LMNA,RAD23B,PDE6D |
| 3.039e-02 | -3.49 | NR0B2 (nuclear receptor subfamily 0 group B member 2) | protein interactions | 8431 | 72 | 28 | 19454 | 5460 |
VCPIP1,EID1,SMAD4,TRAF6,HNRNPA1,HDAC6,SMARCE1,AR,NR1I2,MDM2,ESR2,NR1H2,SP2,RXRG,SIN3A,PAX9,SMARCB1,PPARG,XBP1,VDR,TP53,PIAS1,HDAC3,RBP5,NR1I3,GPSM3,PLSCR1,SIRT7 |
| 3.039e-02 | -3.49 | Srsf1 (serine and arginine-rich splicing factor 1) | protein interactions | 110809 | 72 | 28 | 19454 | 5460 |
PPIG,THOC6,CRTAP,SNRNP70,RBM27,RNF40,APOBEC3B,VIRMA,COPS7B,SNRPD3,THOC1,CCNF,THOC2,HNRNPH3,WTAP,NCOA5,P3H1,ZNF326,TRAF2,ZC3H14,POLDIP3,DHX16,ZC3H11A,SRSF8,THOC3,DDX39B,RBM3,HNRNPA2B1 |
| 3.039e-02 | -3.49 | MIR18A (microRNA 18a) | protein interactions | 406953 | 72 | 28 | 19454 | 5460 |
TRA2A,NONO,HNRNPA1,APOBEC3B,DDX1,IGF2BP1,CRTAP,EIF2AK2,SYNCRIP,CPSF1,HNRNPL,FAM98A,MATR3,RBFOX2,SF3A1,SART3,NUFIP2,RARS1,HNRNPH3,RTCB,SF3B1,HNRNPA2B1,G3BP2,MARS1,HNRNPK,HNRNPA0,TRA2B,HNRNPF |
| 3.039e-02 | -3.49 | PPARGC1A (PPARG coactivator 1 alpha) | protein interactions | 10891 | 72 | 28 | 19454 | 5460 |
PML,NR1I3,EP300,EWSR1,RNF34,FBXW7,SRSF2,SKP1,BCL6,PIAS1,SRSF4,TP53,NFE2L1,PPARA,PPARG,MYEF2,CDK6,UBE2I,MED17,NDN,VIRMA,ESR2,NR1I2,CREBBP,TNFAIP3,NFKB1,MED21,NR4A2 |
| 3.039e-02 | -3.49 | JMJD1C (jumonji domain containing 1C) | protein interactions | 221037 | 72 | 28 | 19454 | 5460 |
H2AZ1,CCNF,PHF21A,HNRNPL,NUP35,SRPK2,VIRMA,ESR2,EGLN3,CNOT2,MYC,AR,TXNIP,GADD45A,PML,RPA3,TRIM37,H3C1,PSMC1,MT2A,SUPT5H,SOX2,RPN1,RPA2,KLF3,PPARG,RNF8,RBPJ |
| 3.039e-02 | -3.49 | MINDY4 (MINDY lysine 48 deubiquitinase 4) | protein interactions | 84182 | 72 | 28 | 19454 | 5460 |
BAG2,SF3B1,RUVBL2,TRIM21,TCOF1,CCT8,EIF3E,RPL4,EEF1G,HNRNPF,DDX39A,PPP2R1A,TP53,NFKBIL1,IFT57,IFT172,RPLP2,SF3B4,SSBP1,RPL10,RPL22,POLR2B,RPL13A,SNRPA1,PPIB,PRPF19,UBE2H,CCT2 |
| 3.039e-02 | -3.49 | RTF2 (replication termination factor 2) | protein interactions | 51507 | 72 | 28 | 19454 | 5460 |
CDK6,HNRNPL,TCEAL1,UBE2L3,RASL11A,ESR2,ZBTB2,MYC,NTAQ1,BAG3,PTGER4,KDM2A,UBE2H,NOSIP,PML,FLYWCH2,LDLRAD4,EP300,KDM4B,H3C1,KRAS,TOLLIP,DDI1,ATG16L1,IL1R2,MND1,DMAP1,PIH1D1 |
| 3.039e-02 | -3.49 | MAP1LC3C (microtubule associated protein 1 light chain 3 gamma) | protein interactions | 440738 | 72 | 28 | 19454 | 5460 |
GABARAPL2,ATG16L1,SF3A1,STX17,SAMM50,TFCP2,SQSTM1,TRIM21,GABARAP,ATG7,TP53INP1,ATG101,OPRM1,ZNF24,CUL3,TRIM32,RB1CC1,TBC1D25,ATG3,LMNB1,CCT2,TSR2,ACTA2,OPTN,KBTBD6,STK3,TAX1BP1,TCP1 |
| 3.040e-02 | -3.49 | H2BC5 (H2B clustered histone 5) | protein interactions | 3017 | 169 | 59 | 19454 | 5460 |
MSX2,H2AX,ASPM,TOP3B,H2AJ,CHMP4C,NECAP1,RPN1,MRPS18B,RUVBL2,PPAN,MAP1B,MSH6,MEPCE,UBE2A,VDAC1,HDAC6,CD81,GRSF1,HMGA1,HNRNPD,NCK1,H2AC4,KRR1,SSBP1,DNM2,H2AZ1,SRP14,ELK4,TRIM36,HEXIM1,SSR1,NUP50,RNF113A,SQSTM1,SMG5,PRKCB,CWF19L1,PPM1G,HIRA,NOP53,STAU1,UFL1,KDM1A,RPS29,BTF3,ICAM1,PDCD4,ATG3,PSMD14,FGFBP1,PRKRA,CTTN,CCNF,VIRMA,ESR2,NCKAP1,RPL7L1,RPL35 |
| 3.040e-02 | -3.49 | large ribosomal subunit rRNA binding | molecular function | GO:0070180 | 5 | 4 | 18094 | 5411 |
MRPL11,RPL12,RPLP0,RPL23 |
| 3.040e-02 | -3.49 | CXCR3 chemokine receptor binding | molecular function | GO:0048248 | 5 | 4 | 18094 | 5411 |
CXCL11,CXCL9,CXCL13,CXCL10 |
| 3.040e-02 | -3.49 | glutathione disulfide oxidoreductase activity | molecular function | GO:0015038 | 5 | 4 | 18094 | 5411 |
GLRX2,GSTO2,GLRX,GSTO1 |
| 3.040e-02 | -3.49 | isocitrate dehydrogenase [NAD(P)+] activity | molecular function | GO:0004448 | 5 | 4 | 18094 | 5411 |
IDH3B,IDH1,IDH3A,IDH2 |
| 3.040e-02 | -3.49 | insulin binding | molecular function | GO:0043559 | 5 | 4 | 18094 | 5411 |
C2CD2L,PIK3R1,IGF1R,IDE |
| 3.040e-02 | -3.49 | leukotriene-C4 synthase activity | molecular function | GO:0004464 | 5 | 4 | 18094 | 5411 |
MGST2,GSTM4,ALOX5AP,MGST3 |
| 3.042e-02 | -3.49 | Osteoclast differentiation | KEGG pathways | hsa04380 | 129 | 55 | 7161 | 2463 |
JUNB,JUN,AKT2,STAT1,TYROBP,MITF,PIK3CA,TNF,IL1B,TAB2,MAP2K6,PPARG,PIK3R3,AKT1,PIK3R2,SOCS3,PIK3R1,FOSL2,IRF9,LILRA2,FCGR2A,IFNAR1,MAPK10,TRAF2,FCGR1A,IKBKB,IFNGR1,NFKB1,TGFBR2,IFNB1,AKT3,PPP3CA,MAP2K1,STAT2,TRAF6,LCP2,LILRB1,IL1A,LILRA1,TAB1,LILRA3,ACP5,LILRB4,IFNG,SYK,CTSK,CREB1,FOS,TGFB2,FCGR2B,MAP3K14,SQSTM1,JAK1,PPP3R2,NFKBIA |
| 3.042e-02 | -3.49 | Osteoclast differentiation | KEGG pathways | ko04380 | 129 | 55 | 7161 | 2463 |
TGFB2,FOS,CREB1,CTSK,SYK,IFNG,LILRB4,ACP5,NFKBIA,PPP3R2,JAK1,SQSTM1,MAP3K14,FCGR2B,STAT2,TRAF6,MAP2K1,PPP3CA,AKT3,IFNB1,TGFBR2,NFKB1,LILRA3,TAB1,LILRA1,IL1A,LCP2,LILRB1,FOSL2,IRF9,PIK3R1,SOCS3,PIK3R2,AKT1,IFNGR1,IKBKB,TRAF2,FCGR1A,MAPK10,FCGR2A,IFNAR1,LILRA2,MITF,TYROBP,STAT1,AKT2,JUN,JUNB,PIK3R3,PPARG,MAP2K6,TAB2,IL1B,TNF,PIK3CA |
| 3.045e-02 | -3.49 | MVK (mevalonate kinase) | protein interactions | 4598 | 57 | 23 | 19454 | 5460 |
PPP1CB,NUDT3,RPA2,ACAA2,RPA3,TRUB1,HSPA8,ABCE1,EWSR1,MTDH,NAB1,KRAS,PRPS1,RIGI,MOV10,ANKRD49,UBFD1,RIT1,ENO1,PBDC1,GMDS,APEX1,RNF141 |
| 3.045e-02 | -3.49 | ZNF280C (zinc finger protein 280C) | protein interactions | 55609 | 57 | 23 | 19454 | 5460 |
TP53,CBX3,LMNA,RPA2,NLE1,KDM1A,H3C1,NUCKS1,RAB8B,MYC,HMGA1,CIAO1,DCAF4,H2AZ1,TNFRSF1B,ZNF330,ZMYM2,EED,SNRNP40,CBX5,APEX1,ZBTB2,CEP19 |
| 3.045e-02 | -3.49 | USP46 (ubiquitin specific peptidase 46) | protein interactions | 64854 | 57 | 23 | 19454 | 5460 |
WDR77,UBA52,CHRM3,FAXC,MYL6,SHOC2,HSPA8,MAVS,ATG9A,PGAM1,H2BC9,YWHAH,XPO1,YWHAG,STK4,CIRBP,WDR20,YWHAZ,YWHAB,GRIA1,SNX2,ACTB,UBB |
| 3.045e-02 | -3.49 | PSMG4 (proteasome assembly chaperone 4) | protein interactions | 389362 | 57 | 23 | 19454 | 5460 |
PSMG3,CCDC69,POMP,MRPS34,PSMB7,PSMG2,PSMB9,RPP21,GLO1,IMP3,PSMB3,PSMA4,CA10,PSMA2,PSMA1,KRAS,PSMA5,GMDS,RASL10B,PSMG4,ZMAT5,AVPI1,AMACR |
| 3.045e-02 | -3.49 | ZBTB3 (zinc finger and BTB domain containing 3) | protein interactions | 79842 | 57 | 23 | 19454 | 5460 |
SNX1,WDCP,SMAD3,TRAF7,ZMYM2,ZBTB18,SPOP,PKNOX1,AP2A1,IRF6,SNX5,PROX1,BAG3,EIF5B,FXR2,AP1M1,AHCYL1,KLHL23,KLHL28,PPARG,TRAPPC13,SUPT5H,DDX39A |
| 3.045e-02 | -3.49 | COMMD6 (COMM domain containing 6) | protein interactions | 170622 | 57 | 23 | 19454 | 5460 |
SCLT1,E2F6,STMN2,COMMD3,COMMD8,NUP62,SSRP1,CCAR1,COMMD2,SF3B1,ARGLU1,CNKSR3,CCDC22,COMMD9,COMMD5,SUB1,RBM17,NFKB1,VPS26C,COMMD6,RBMX2,RSRC1,PSPC1 |
| 3.045e-02 | -3.49 | ANKRD13D (ankyrin repeat domain 13D) | protein interactions | 338692 | 57 | 23 | 19454 | 5460 |
TNFAIP3,LHFPL6,TMEM255A,ATP6V1D,CLDN3,NRSN1,UBTD1,SMURF1,RALA,KCNMB2,CTDSP2,TOP3B,CSNK1G3,ZNRF1,IZUMO1,TMEM31,SYS1,LDLRAD4,MTDH,WBP2,RNF11,MRGPRX4,NEDD8 |
| 3.045e-02 | -3.49 | CSF1R (colony stimulating factor 1 receptor) | protein interactions | 1436 | 57 | 23 | 19454 | 5460 |
PIK3R2,NEDD8,KIT,POLDIP3,ITGAV,INPPL1,PIK3CA,CTDSP1,HGS,GRAP2,CTDSP2,SOCS3,YES1,GSTCD,SRC,VIRMA,FBXW11,SHC1,CBL,EPHA2,HSP90AA1,PIK3R1,GORASP2 |
| 3.045e-02 | -3.49 | ITK (IL2 inducible T cell kinase) | protein interactions | 3702 | 57 | 23 | 19454 | 5460 |
TCOF1,HNRNPK,KPNA2,FASLG,FGFR1,MET,WDCP,ITK,GAB1,DYNC1I2,SRC,CD2,HSP90AB1,SMURF1,CD28,LCP2,PPIA,SFN,PIK3R1,CSK,SMAD4,HSP90AA1,CBL |
| 3.045e-02 | -3.49 | KRT7 (keratin 7) | protein interactions | 3855 | 57 | 23 | 19454 | 5460 |
INA,APEX1,VIRMA,CDK9,RNF208,TES,DCAF4,UBE2H,HDAC6,TRIM37,HMGB1,KDM1A,TNF,MEPCE,DDX39B,UBE3A,PCNA,NEFL,METTL14,HEXIM1,ERLIN2,CFTR,IGFBP3 |
| 3.046e-02 | -3.49 | gland development | biological process | GO:0048732 | 424 | 143 | 18204 | 5365 |
ARHGAP5,TAF10,PIK3CA,UBE3A,BAX,IL6,CREB1,ID4,SFRP1,CDC42,SOD2,SOCS2,EXT1,SRSF1,FGFR1,AKT2,FRZB,PRL,PRDX2,RB1CC1,UGT1A1,NME1,HNF1B,DAG1,SRC,APLN,ERRFI1,PHB2,CCL11,ACO2,UPRT,FOXI3,RPS15,ELK1,SOX3,PAX6,CAV1,SRP54,BMPR1A,EDNRA,SMARCB1,GUCD1,VEGFA,EZH2,TCF21,DKK3,PCK2,TSPO,CDKN1B,CUL3,ZMPSTE24,NR0B1,CDO1,SMAD2,PGR,LIPA,MSX2,CLDN1,PSEN1,TWSG1,NOTCH2,CRIP1,TNF,UCP2,LBH,SLC6A3,POLB,TGFB2,WDR77,SMAD3,RAF1,IL10,RBPJ,WNT2,HNRNPD,CTNNB1,FGF10,RHBDD3,MSX1,VDR,PCNA,SEC63,IRF6,OXTR,FA2H,FGF7,SOX2,AKT1,EPHA2,FEM1B,TGFB3,NKX3-1,PRMT5,EAF2,STAT6,NOG,HAND2,STK11,PROX1,SEMA3C,ITGA2,SMAD4,NHERF1,JAK2,MPST,PML,POU1F1,SOSTDC1,NRP1,PCSK9,RPGRIP1L,CDK5RAP3,NFKB1,MAP2K1,CACNB4,RAG1,TYMS,CRHR1,GJA1,CD2AP,XBP1,RGN,MET,DDR1,LMO4,CEBPG,SOX9,CYP1B1,FKBP4,ALDH1A3,SLC29A1,ARF6,CCND1,TGFBR2,SOD1,ACAT1,AR,CYP1A1,STAT5A,MSN,CAPN1,CRKL,UMPS |
| 3.046e-02 | -3.49 | growth | biological process | GO:0040007 | 424 | 143 | 18204 | 5365 |
DIPK2A,ACVR1C,TIAM1,TAF10,STK4,CLIC4,ALCAM,KPNA1,FKBP8,UBE3A,TP53,TNFAIP6,SFRP1,ASPM,LEPR,FGFR1,EXT1,COMT,HELT,HNF1B,COPS2,TMEM38B,TBCE,SRC,ADRA1A,LARGE1,LAMB2,DAG1,CCL11,SPRY1,PTPN11,HEY2,LEP,CER1,SLC4A10,STK3,S100B,MTPN,BMPR1A,EDNRA,RC3H2,LLPH,BCL9,SLITRK1,WNT10B,MIR195,SEMA7A,EIF4H,LHX2,IL7,TAL2,MSTN,EZH2,EFNA5,NCAPG2,IMPACT,RUNX1,ZMPSTE24,SMAD2,CPNE1,FXN,EMX1,MSX2,SELENON,PTN,CD9,CD81,NBN,MTM1,EP300,STC1,NOTCH2,IGF1,SMAD3,GINS4,MIR24-1,TGFB2,PAK6,CCN3,CTNNB1,FGF10,WNT2,CCM2,SLC1A2,NPR2,MAP1B,TMEM108,THBS3,GPX1,CYFIP2,RMI1,FGF7,SELENOM,COL3A1,WNT7A,PPP3CA,SOX2,KLK6,SAV1,CDK5,TMEM182,PTK7,SEMA5A,HDAC6,PLG,C9orf72,MIR23A,STK11,SMAD4,FKRP,SMAD1,TTC8,BMPR1B,NPPC,NDN,FGF1,PELO,CDKN1A,NRP1,FOSL2,KCNJ8,PRMT2,SSNA1,RDH10,TYMS,WDR11,CD2AP,GJA1,DDR1,TNR,FLRT3,SOX9,VPS54,TGFBR2,FOXC2,GAS2,ETNK2,NRN1,RND2,AR,IFRD1,CHST11,NINJ1 |
| 3.046e-02 | -3.49 | developmental growth | biological process | GO:0048589 | 424 | 143 | 18204 | 5365 |
ZMPSTE24,RUNX1,IMPACT,SMAD2,CPNE1,FXN,SELENON,MSX2,EMX1,CD9,PTN,NBN,MTM1,CD81,S100B,MTPN,BMPR1A,SLITRK1,WNT10B,EDNRA,RC3H2,BCL9,LLPH,MIR195,EIF4H,SEMA7A,LHX2,IL7,TAL2,EFNA5,NCAPG2,EZH2,MSTN,FGFR1,EXT1,TBCE,TMEM38B,COPS2,COMT,HELT,HNF1B,LARGE1,LAMB2,DAG1,ADRA1A,SRC,SPRY1,CCL11,HEY2,PTPN11,SLC4A10,STK3,CER1,LEP,TIAM1,TAF10,ACVR1C,DIPK2A,STK4,CLIC4,ALCAM,TP53,UBE3A,KPNA1,FKBP8,TNFAIP6,SFRP1,LEPR,ASPM,CD2AP,GJA1,DDR1,TNR,SOX9,FLRT3,GAS2,TGFBR2,VPS54,FOXC2,IFRD1,ETNK2,NRN1,RND2,AR,NINJ1,CHST11,BMPR1B,NPPC,SMAD1,TTC8,FGF1,NDN,NRP1,CDKN1A,PELO,FOSL2,RDH10,SSNA1,PRMT2,KCNJ8,TYMS,WDR11,SELENOM,RMI1,FGF7,SOX2,COL3A1,PPP3CA,WNT7A,SAV1,KLK6,PTK7,CDK5,TMEM182,SEMA5A,HDAC6,STK11,MIR23A,PLG,C9orf72,FKRP,SMAD4,STC1,NOTCH2,IGF1,EP300,MIR24-1,TGFB2,SMAD3,GINS4,PAK6,CTNNB1,FGF10,CCN3,WNT2,NPR2,MAP1B,TMEM108,CCM2,SLC1A2,CYFIP2,THBS3,GPX1 |
| 3.046e-02 | -3.49 | RAF-independent MAPK1/3 activation | REACTOME pathways | R-HSA-112409 | 23 | 12 | 10285 | 3229 |
PTPN11,DUSP9,CDK1,MAP2K1,JAK2,PEA15,DUSP10,DUSP1,IL6ST,DUSP6,IL6,JAK1 |
| 3.046e-02 | -3.49 | PI-3K cascade:FGFR2 | REACTOME pathways | R-HSA-5654695 | 23 | 12 | 10285 | 3229 |
FGF7,FGF1,FGF10,FGF17,FGF3,FGF16,PIK3R1,FGF22,PIK3CA,GAB1,PTPN11,FGF23 |
| 3.046e-02 | -3.49 | Dopamine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-212676 | 23 | 12 | 10285 | 3229 |
CASK,SYN3,LIN7B,VAMP2,CPLX1,PPFIA3,STXBP1,PPFIA2,RAB3A,SNAP25,LIN7C,STX1A |
| 3.047e-02 | -3.49 | positive regulation of telomere maintenance via telomerase | biological process | GO:0032212 | 35 | 16 | 18204 | 5365 |
TCP1,CTNNB1,CCT5,NEK7,CCT8,XRCC5,CCT7,TNKS2,CCT2,NEK2,DKC1,MAPKAPK5,PRKCQ,TNKS,PKIB,HNRNPA1 |
| 3.047e-02 | -3.49 | walking behavior | biological process | GO:0090659 | 35 | 16 | 18204 | 5365 |
HEXA,FXN,CACNB4,DRD1,CEND1,FKRP,CLN8,HTRA2,ZMPSTE24,LARGE1,EPHA4,KLHL1,GLRA1,KCNJ10,GLRB,ABHD12 |
| 3.047e-02 | -3.49 | regulation of toll-like receptor signaling pathway | biological process | GO:0034121 | 35 | 16 | 18204 | 5365 |
RNF115,BIRC2,LGR4,MIR146A,NFKBIL1,CD36,IRF4,S100A8,IRF1,LRRC14,TASL,SARM1,MIR17,GFI1,IRF7,NLRP6 |
| 3.047e-02 | -3.49 | behavioral fear response | biological process | GO:0001662 | 35 | 16 | 18204 | 5365 |
NR2E1,BRINP1,COMT,HTR1A,LARGE1,USP46,MECP2,VDAC1,SLC1A1,EIF4E,DPP4,DRD1,ASIC1,NEUROD2,GNG7,ATP1A2 |
| 3.047e-02 | -3.49 | regulation of interleukin-4 production | biological process | GO:0032673 | 35 | 16 | 18204 | 5365 |
CD28,IRF4,CD40LG,IL1RAP,DDIT3,CD86,IL20RB,CD83,MIR320A,SASH3,SYK,NDFIP1,FCER1G,NLRP3,FOXP3,PRKCQ |
| 3.047e-02 | -3.49 | integrated stress response signaling | biological process | GO:0140467 | 35 | 16 | 18204 | 5365 |
EIF2S1,CREB3,ATF4,BATF,DDIT3,CREBZF,CEBPE,JUNB,NFE2L2,FOS,JUN,NFE2,IMPACT,RPAP2,DELE1,CEBPG |
| 3.047e-02 | -3.49 | negative regulation of fibroblast proliferation | biological process | GO:0048147 | 35 | 16 | 18204 | 5365 |
GSTP1,SFRP1,TP53INP1,MYC,TRIM32,LTA,BAX,NUPR1,B4GALT7,FTH1,SOD2,CDC73,CAV1,MED31,TP53,ING5 |
| 3.047e-02 | -3.49 | positive regulation of myeloid leukocyte cytokine production involved in immune response | biological process | GO:0061081 | 35 | 16 | 18204 | 5365 |
SEMA7A,CD36,PYCARD,TLR4,SYK,TICAM1,MIF,RIGI,TLR7,MYD88,MAVS,TLR3,BCL10,DDX1,LILRB1,KIT |
| 3.047e-02 | -3.49 | granulocyte activation | biological process | GO:0036230 | 35 | 16 | 18204 | 5365 |
FCER1G,KARS1,MYD88,VAMP8,CCL3,IL15,TYROBP,IL18,CCL5,CXCL8,VAMP2,SYK,VAMP7,CAMP,LILRA2,TRAF3IP2 |
| 3.049e-02 | -3.49 | negative regulation of leukocyte differentiation | biological process | GO:1902106 | 110 | 42 | 18204 | 5365 |
TMEM176A,UBASH3B,MYC,TNFAIP6,CTNNB1,TOB2,CBFB,SFRP1,TLR3,RC3H2,FBXO7,ADIPOQ,IFNB1,MIR21,IFNA2,MIR30B,CARTPT,CDK6,TRIB1,GPR137,INHA,TLR4,CTLA4,LILRB4,FBXW7,FCGR2B,FGL2,IL2,TCTA,BCL6,IRF1,TMEM176B,FOXP3,IL4,LILRB1,C1QC,PIK3R1,HMGB1,RUNX1,PRDX2,SOCS5,CCL3 |
| 3.049e-02 | -3.49 | cytosolic transport | biological process | GO:0016482 | 131 | 49 | 18204 | 5365 |
TMED9,STX16,TRIM27,VPS26A,PHETA2,RAB6A,RAB14,TMEM87A,VPS26B,RAB9A,RAB6B,YKT6,GOSR1,STX10,SURF4,RAB29,PREPL,PPFIA2,SNX5,STX5,RGP1,AP2A1,KIF1C,ACTR2,BET1L,VAMP3,SYT4,VPS54,SNX3,TRAPPC10,RHOBTB3,TBC1D5,LMAN1,RAB9B,SNX12,STX6,TBC1D17,SNX1,SYS1,VTI1B,SRSF10,TBC1D10C,SLC66A2,RNF126,PLEKHJ1,EHD3,SYBU,SNX2,AP1AR |
| 3.053e-02 | -3.49 | SYNRG (synergin gamma) | protein interactions | 11276 | 69 | 27 | 19454 | 5460 |
GSK3A,AP1G2,SMAP2,STX6,UBA3,VIRMA,AFTPH,YWHAH,XPO1,YWHAG,ATG9A,MLF1,SFN,RAB11A,YWHAB,LAMTOR1,YWHAZ,MYO6,APPBP2,PML,STX7,STAU1,MAP1LC3B,TOP3B,AP1S2,VAPB,RAB4A |
| 3.053e-02 | -3.49 | NCR3LG1 (natural killer cell cytotoxicity receptor 3 ligand 1) | protein interactions | 374383 | 69 | 27 | 19454 | 5460 |
STX8,SCPEP1,ERG28,TNF,SLC7A1,SLC31A1,PLPP6,PDCD1LG2,PSMB3,DSTYK,TNPO2,SEC14L1,ZER1,IL20RB,EIF1AX,MET,SNX17,XPO5,MGST3,VIRMA,GGPS1,CD200R1,TSPO,DPP4,TOMM40,LGALS8,DEGS1 |
| 3.053e-02 | -3.49 | MIR140 (microRNA 140) | protein interactions | 406932 | 69 | 27 | 19454 | 5460 |
G3BP2,MARS1,TRA2B,HNRNPA0,HNRNPF,HNRNPK,SF3B1,HNRNPH2,RTCB,HNRNPA2B1,HNRNPH3,RARS1,RBFOX2,PIP5K1A,HNRNPL,FAM98A,MATR3,SYNCRIP,EIF2AK2,DDX1,IGF2BP1,CRTAP,HNRNPA1,NONO,TRA2A,APOBEC3B,KARS1 |
| 3.053e-02 | -3.49 | PCYT1A (phosphate cytidylyltransferase 1A, choline) | protein interactions | 5130 | 69 | 27 | 19454 | 5460 |
FAM20C,PCYT1B,ATG7,LMNB1,RIT1,LSM3,GYS1,ACOX1,RAC2,ACTB,VIRMA,DYRK1A,VKORC1L1,AGTRAP,MTMR6,SNAPIN,CDC42,LMNA,SDCBP,RNF8,MOB3C,PIH1D1,BAP1,PDIA6,NUP50,LSM12,STX11 |
| 3.053e-02 | -3.49 | EVL (Enah/Vasp-like) | protein interactions | 51466 | 69 | 27 | 19454 | 5460 |
TP53,ATG16L1,CFTR,CDK7,CRKL,RPS23,EXD2,ZYX,MRFAP1,FXR2,RAD21,ZDHHC17,BAG3,ETFRF1,XPO1,MYO6,RPL23,UBP1,NAP1L5,TES,ZNF655,TRAF7,SPTAN1,HNRNPL,RABIF,SRC,TRMT61A |
| 3.053e-02 | -3.49 | MTM1 (myotubularin 1) | protein interactions | 4534 | 69 | 27 | 19454 | 5460 |
AKR7A2,CCT5,SAMM50,MTMR2,HECTD1,HSPD1,TMX3,KRAS,CSK,MTMR12,PMPCA,CIAO1,STOML2,EDEM1,YWHAH,PSMD1,PSMD7,HAX1,ILK,CALU,GANAB,SNX17,MTM1,SNX2,CHCHD3,CCT7,BTG3 |
| 3.053e-02 | -3.49 | TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3) | protein interactions | 10312 | 69 | 27 | 19454 | 5460 |
ICA1,AP3S2,ATP6V1D,ATG9A,TMEM199,WWP2,SLC30A5,TTC9C,NDFIP1,ATP6AP2,SYNCRIP,ADCY3,CSNK1G3,ATP6V1C1,EMC1,ERLEC1,RPS15,ATP6V1G2,ABCC2,GOLGA7,CYTH2,FLOT1,ADD2,TMX2,ABCB9,EWSR1,MTDH |
| 3.053e-02 | -3.49 | organic cyclic compound binding | molecular function | GO:0097159 | 6285 | 1935 | 18094 | 5411 |
SYN3,CLPB,PDE4B,RPS7,ZSCAN25,RASL10B,IP6K1,TYMS,ACAT1,LSM4,GTPBP1,CPSF2,TRIM21,BRD9,PGS1,SNRPA1,POLR2L,FAM98A,UNC50,FKBP2,RNASE1,HMG20A,H2BC9,TRNP1,SMCHD1,RIGI,RMI2,GEMIN7,LBR,LYAR,JUN,NUP42,SNIP1,EDC3,NLRP2,MIR877,BTF3,IKZF5,NT5C2,CALR,RPA3,PPP1R10,NUFIP2,DDX5,STRBP,GPT,HADHA,ACACA,EPHX1,FOXS1,MPG,MIR150,PAK2,RPS24,ANP32A,MIR187,ELAVL4,MTA3,IRF8,SOX14,RAB8B,KDM1A,HSD11B1,NHEJ1,EHD1,VDAC1,LANCL2,RALB,R3HCC1,LEP,ATP2C1,DROSHA,FTSJ3,PROM1,MIR1224,UBE2I,UTP23,SBK2,SEPHS1,GPN2,BMPR2,CERS2,DIRAS2,SUB1,PAQR9,MIR99B,APEH,CYGB,EMG1,ACADS,PNO1,MMAA,PHC1,RPL39,CFTR,IFIT2,ZKSCAN1,LIG3,RASD1,MIR192,ATXN1L,MAK16,SSBP4,IKZF2,SEPTIN7,GNA14,HSD17B1,FYTTD1,MIR15A,RERG,HINT2,SNRPD1,SMC4,RBFOX2,HUWE1,H2AB1,SORD,BOLL,CIART,LSM10,CHTOP,RPL8,MORC2,TAF9,CDC40,NUDT16,ZNF451,NKRF,UCKL1,RPL24,DUS4L,ZBTB14,SNRNP40,H1-3,POU3F4,ARL11,RXRG,PHYH,AK3,MPHOSPH10,KDM2A,POLE4,ZNF343,HNRNPA0,FOLR2,HELLS,MIR96,TOX,POLR2G,EIF2B3,RAB3B,PPAN,ACVR1,ZNF397,TRIM24,RRAGB,APEX1,HNRNPF,SNRNP27,MIR10A,TRIM26,PHF21A,TFDP2,PEBP1,NEK9,TSN,CLCN6,MIR125A,HEY2,RASL10A,FLYWCH2,POU1F1,LHX2,MCM6,HMCES,FBP1,FMO2,DNTT,APEX2,DAPK3,MITF,RPS15,HTR1A,MINAR2,MIR493,HSP90B1,ADCY3,RHOH,TACO1,MIR363,POLB,EGLN3,SLC6A4,ZBED3,MFAP1,ZBTB39,GNMT,BLVRA,SNAPC3,MRPL13,ZNF688,ZBTB16,MEIOB,ACTB,RPL7A,DHX16,RUNX1,HINT1,ETNK2,AKAP1,DNAJC2,ACSS2,ACADSB,RFXANK,JAK1,MRPL23,NOA1,MIR208B,ZBTB2,ACO1,RAB35,TRIM32,PPIL4,CYP11B2,TRIM27,MIR183,CDK4,KCTD12,MIR661,MIR491,CCDC25,MRPS28,RFX5,THAP1,MIR191,CBR4,MRPL12,APOBEC3B,UTP6,RPS16,TRIR,SP1,UGDH,UBE2D1,YWHAZ,SYK,ZHX3,SWAP70,HMGN4,RPS3,GCFC2,MIR374A,MIR657,CYB561D2,MRPS23,RRN3,UBE2L3,EIF3G,MAP2K3,PRPF31,MAX,SRXN1,KIF3C,FOXP2,RAP2B,CPSF4,RBBP7,MIR194-1,TSSK1B,ZYX,DTD2,SMAD3,WDR3,EHD4,RBBP4,BHLHE40,TST,GTF2E2,NCOA5,TENT5C,EPHA4,RRAS2,CYP11B1,SNAI3,UBE2W,KIN,UGT1A1,DDIT3,TCOF1,OLA1,PGRMC1,VPS4A,P2RY1,TUFM,ZNF326,KCNJ8,RPS27L,KLF1,RBFOX3,GTF2IRD1,NPM3,CERS6,AGO1,RAMAC,SNRPB2,PIWIL2,RASL11A,RAB33A,MAP3K21,MIR383,DXO,MIR215,JUNB,CARHSP1,UPRT,STK4,HBB,ADD1,AR,MRPS17,DTYMK,HSPA5,MIR193B,MOV10,GFOD2,TOPBP1,ELF5,STN1,ZNF518B,NKX6-2,LSM8,TNRC6C,RND2,SURF6,RHOB,TIA1,CYP4F12,GK5,OAS1,RABL2B,RNASEH1,RAB3A,HNRNPD,ZNF770,ALB,PSPC1,SRSF10,MIR211,SPHK2,TLR7,UBE2E3,HMOX2,ATF4,RAB30,MIR640,E2F6,RPL15,TFPT,PML,NUDT2,DDX39B,SREK1IP1,PTK7,SPATS2L,ADRB3,ITM2B,PLSCR1,RAB11B,NOL7,GMPS,RPL28,TOP2B,ZNF622,FAM20C,UBE2G2,RTN4,PIWIL4,DTD1,MIR34C,GNAI3,SNRPN,DRG1,ZNF575,ACBD6,TIGD7,EGR1,MTA2,MIR140,RPS13,ALKBH3,E2F4,FAM133B,POR,SRP72,SOX3,EIF5B,RAP1B,THUMPD1,RPL32,EEF2,CELF6,MTERF2,NONO,HTR5A,MIR181C,UTP15,KCNIP3,NDN,ZNF511,RAB14,CASK,MRPS18C,MIR148B,MIR214,MAEL,GTF2I,MTRF1,RNASEL,UBE2A,TOX4,MFN1,H1-5,ATF3,MIR223,RBM7,RAB27A,RBMS2,PNPLA8,TCF23,MARS1,ADGB,RPL23,CDK6,TFE3,RPSA,LGALS3,PHYKPL,POLR2F,RPL19,THOC6,FKBP10,MIR429,LSM12,PIH1D1,MAP4,MIR455,H1-10,CYP17A1,RPL7,MRPS35,COPS5,KCNJ10,DRAP1,NLRP6,FUBP3,FOXJ3,SECISBP2L,TRMT1L,RBM12,EPHA2,NKIRAS2,CYP3A43,POLDIP2,HNRNPK,MBD5,HSPD1,CSRP1,IDE,MIR146A,THOC1,STARD4,BCKDK,NR4A2,EIF3K,ZNF704,FPGT,SUPT5H,MIR335,MGMT,TOR1B,RIOK2,ATP1A1,NGRN,RAB18,MAP2K1,BANF1,EIF3D,SNAPC1,PABPC1,SERPINA3,NFIL3,CDC42,ARCN1,MIR23A,PCK2,TES,CRYL1,LMNB1,CYP26A1,EXOSC4,GMPPB,SMAD5,MIR625,MEPCE,HNRNPA1,CYP1A1,ISG20,MAP3K11,LRWD1,RPL12,GK2,SOCS3,NR2F6,RHOBTB1,CDK17,ZBTB45,AKT2,CYB5D2,SRFBP1,BRAP,CNP,HSPE1,TCEA1,PNPO,POLR2C,CLK1,TFIP11,NUDT1,ENDOD1,STAT2,HTR2A,SNRPD3,NAA15,MIR193A,PRKCE,ZNF24,RHOU,CEBPG,COQ8A,PRMT5,CREB3,BRCA1,TRUB1,MIR373,CYB5R4,IMP3,MXI1,SSBP3,EXD2,RNF10,HEXIM1,BMPR1A,MIR155,SSBP2,SLC38A9,TOR4A,GTF2F2,IER2,DMTF1,FHIT,NOP16,TOPORS,RFC3,ZNF692,H2BC17,RNASE4,POP7,RAP2C,MIR130B,MIR200C,IREB2,DDX23,KLF9,MSX1,ZNF507,CYP39A1,GTF3C4,MIR32,SLPI,TXN,MIR920,HDAC5,H2BW1,FAM20B,DBR1,PRKCB,AGGF1,MIR152,GNAZ,APOBEC3A,DYRK1B,SMAD1,RHEB,ATP5F1B,BCS1L,MAP2K6,MAPKAPK3,NQO1,TEX19,ZNF22,RAD1,NEK7,PAX9,FERD3L,MIR186,ZNF526,FA2H,MSL2,RAB23,DBH,MIR25,MIR132,ADCY2,PREB,LMBRD1,RRP7A,CCT8,TOP1,WEE2,CLPX,API5,MIR548C,MXD1,MYC,CTBP1,FOXC2,MPPED2,EDF1,PGBD2,CTU1,GATAD1,RBM41,OTX2,AUH,ZNF790,ATP5F1A,KPNA2,YWHAG,MSH6,PSKH1,RBM23,MIR30D,CLP1,RPN1,RPL18,RAB1B,H2AC1,TKTL1,EIF4A2,GNAI2,IDH2,EIF2AK2,CDK1,NFE2L1,PRDM4,ACTR1A,PHKG1,NEK2,SRPK2,TCF21,SLU7,CXXC1,HOXB1,GANAB,EHD3,ZNF32,ZNF668,NGDN,IRF3,ZFP64,THAP8,TWIST2,RUVBL2,MIR320A,DBT,BHLHA9,HNRNPH2,RASL12,RAB5A,CYP2C8,PDIA3,CSK,POLR3H,RIMKLB,ARL10,CDC42EP4,CYB5B,TSEN34,FKBP1A,MRTO4,AKT1,TLR3,PDCD5,CDC5L,LCORL,MIR511,ZMAT3,IDH3B,PAQR8,MRPL40,PRKAG1,NFYB,SART3,RPL26,ATP2B4,MIR147A,MEF2B,PRPS1,EXOSC8,MIR10B,DEK,RPL10,KIF1C,SRSF8,CSNK2A1,RAP1A,BATF,PYM1,RBM17,NUBP2,OXSR1,BMPR1B,ENO1,SMARCA5,HBP1,SF3B5,ARL15,HENMT1,SYP,RPS28,KHDC4,TXNRD2,NDUFS2,HSD17B8,MIR144,CDKL2,STK38,RALYL,MRPL22,STOX2,RPL23A,UBN1,MCM3,MIR28,GMDS,SUMO1,MRPL41,EIF4E3,PSMA6,ZRANB2,RPL27,MACROH2A1,ITK,RPP14,ACTR2,DMPK,SF3B4,RPS9,NR1I3,MIR29A,NKIRAS1,TCEA2,MIR210,MIR425,ZNF319,HNRNPAB,CERK,RAB2A,PAIP2,RRAGA,IGF2BP1,NGB,BCCIP,NR1H2,TOP3B,HTR1F,PDIA2,RB1,CNOT7,MIR873,H2AC7,GTF3C3,IFI16,THRAP3,NACC2,EWSR1,TRIB1,PABPC1L,MIR675,SUMO2,MMUT,MTG1,GIN1,PPIA,PKNOX1,MIRLET7I,RBM27,HOXC4,MIR488,GFI1,HOXD12,ISG20L2,RBM5,RPP25L,MIR639,TAF1D,MIR708,EIF4B,FOSL2,MIRLET7G,ACSL4,CREBZF,TUBB4B,PFKFB2,UBE2N,ZMYM3,R3HDM4,CSTF3,MIR384,CREB1,NUP153,TUBB,FKBP4,CRYM,CKB,ZNF805,MIR221,TFB1M,OSBPL8,ZNF345,TXNRD1,DHRS3,PRR3,MRPL18,ZMYND11,MIR885,CGGBP1,DCTPP1,MIR17,MAPK10,ACVR1C,MIR1298,CYP2F1,SF3B1,CYP2R1,PLAGL1,GAL3ST4,SSBP1,CYP27B1,ERLIN1,MIR145,NKX3-2,TRMT6,TPT1,RPLP0,RAB9A,HAND2,PPME1,ACVR1B,FOXP1,DDX42,POPDC2,MIR551A,ABCF1,ZNF304,TGIF2,TNNI3K,PHAX,ILK,GTPBP2,NR2E1,TDP1,PDCD4,MIR424,STARD3NL,MTRES1,ERO1A,ADSS2,POLR3F,H2BC14,FXR2,PYGM,QRSL1,ZNF687,EIF2B5,RNF20,PWP2,PNMA3,PELP1,RAB9B,NUCKS1,DLX1,TTLL10,RAD23B,FASTKD5,CHRAC1,MIR590,MIR141,HMX2,IMP4,BAP1,ACBD7,TCP1,ELP3,CMTR1,SNRPE,NME1,ZNF175,MIR182,UBE2D3,CRLF3,GAD2,CCAR2,BEND6,RADX,POLR2I,ZNF671,MIR222,PC,TTL,GFM2,SMUG1,DRG2,ETF1,DSTYK,HDAC6,LSM5,RORB,PTPN1,MIR9-1,SRSF1,MYH1,NPR2,EGLN2,TBK1,SMARCB1,NUDT7,SRC,APTX,PMP2,TGIF2LX,PRKACB,EIF4A3,CHKB,EIF2S1,SELENOO,RAB6A,CYP27A1,ZC3H7A,MEF2C,ZNF513,DHX9,KRAS,MIR876,VPS4B,WBP11,TNFAIP3,IDH1,PNP,CRKL,ARL4D,RBM22,TP53I3,RFC5,SAMHD1,ABCB1,NEUROG2,SIRT7,ADAT1,MIR20A,MIR130A,KCNJ11,DIRAS3,TMPO,ZFAND6,SAP30,FARSA,RPS20,CISD1,MYH2,RAB3C,ZC3H15,SYNCRIP,NLRP1,EIF2S2,WBP2,RAB40AL,ZNF189,TRMT11,METAP2,CDC123,IRF2,MIR26B,ZNF263,ARB2A,PPARG,ABCC2,RNF11,PRKD3,YAF2,GIMAP2,MSN,ELK4,TRA2B,POLR1D,DCAKD,QTRT2,USP3,KLF12,MIR205,ZBTB42,NUDT5,GNA11,RAF1,CNOT8,INSIG2,MRPL24,RPS12,KCNAB1,ZSCAN1,CYP1B1,PABPC5,CSNK1A1L,ZNF501,NUPR1,MIR449A,RAB13,RTRAF,NFE2L2,MIR16-1,AKT3,NUP35,FKBP1B,PDAP1,CLK4,RBM3,MRPL10,CCDC86,AGK,CYC1,CCT7,GFOD1,TSNAX,RPF2,IRF4,OAT,GNL1,NT5C3A,RAB4A,ETV6,SMARCE1,NFYA,RBM42,ZCCHC7,ASCC1,EMX1,HINT3,EZH1,MIR153-1,EIF1AD,MCM8,PAPSS2,ZNF740,PAPOLB,TSPO,POLL,RPF1,RIMKLA,LLPH,HEBP2,ROCK1,DICER1,GTPBP8,MAP3K14,MIR99A,BEND5,TERT,MIR30E,NSA2,PPP1R8,ZNF787,ING2,MTF1,ZNF280B,PPIG,APOBEC3C,RPS27A,MDM2,PRM1,RPS4X,XBP1,LUC7L3,CHORDC1,LSM6,PSMC3,ACTA2,STK24,MYEF2,ZNF592,TFCP2,RAG1,MAPKAPK5,RPS10,RTCB,TUBA1A,MIR100,MX2,E4F1,RUVBL1,H2AZ2,HBM,IZUMO1R,CSTF2T,GLUL,MIR21,IDO1,DHX38,MIR296,PPIB,PAK5,RAC2,NOL12,CDK9,ZCCHC10,MAPK4,MRPS11,ZCCHC9,POLR2B,SNRK,CTNNA1,MPHOSPH6,LITAF,ERLIN2,RHOG,HS3ST5,MND1,CMSS1,CYP3A5,H2AX,HEXIM2,FGR,DEDD,SNAI2,TGFBR2,NHP2,H2AC4,PCNA,NOVA1,KIF2A,ZNF655,CYB5R3,RPP25,MTG2,ZBTB17,CRYZ,VRTN,RPL13A,WDR77,HNRNPDL,NTRK3,CYP2C18,THG1L,MIR208A,POP5,PSMC1,PCSK9,ESR2,SNRNP70,MIR1-1,KHDC1,MSX2,SRSF12,ZMYM6,RPL35A,MIR874,ZSCAN5A,ROCK2,POLA2,CDK8,RMI1,TENT2,MAT2A,NMRK1,JAK2,RFX4,FANCG,MIR181D,PRKCQ,HMGB1,MAFG,CYB5R1,TFEB,H2AC6,MYO6,JAKMIP1,H2AZ1,ABCB9,SMG5,ENTPD3,CCT5,EEF1A1,ZBTB18,OGFOD3,DYRK2,RAB31,OARD1,BARX2,VPS72,PHF1,SIX5,KTI12,HMGA1,UBFD1,MYO1B,POLR1B,BAZ1B,CYP21A2,SF3A1,XPOT,FOXA3,H1-1,HSPA14,FOS,IDH3A,AKAP17A,VRK1,PDE2A,THAP2,G6PD,HSP90AB1,MIR126,DYRK1A,SRPRA,CARS1,BCL6,AHCYL1,NFE2,SIN3A,ZHX1,DAPK1,AK5,SOD2,OGDHL,CRY1,PARP2,SMN1,ATAD1,NLRP3,SAR1B,HNRNPH3,CD81,MIR495,EZH2,CYP2C9,NME2,RAB22A,RPS6KA4,MIR3173,HNF1B,PIM2,DUSP14,ZNF177,SPRN,MIDEAS,ETFA,MIR129-1,UCK1,STAT5A,ADCK1,FMO1,MIR638,STARD5,P4HA2,MLH3,RPS11,MIR379,NEUROD2,PRIM2,AGAP2,FGFR1,SLC25A5,ZNF174,ZBTB6,PROX1,ZNF362,PQBP1,ACTR1B,CPSF1,KIF3B,MIR92B,RPP21,PGK1,DPH6,RPL9,NOP58,G3BP2,MIR346,PIK3CG,HADH,EEF1B2,BUD23,GABPA,FOXP3,PSMD4,HR,UBE2E2,LDB1,GCLC,PAK6,SEC63,ZBTB38,SNRPD2,TP53,NR0B1,MIR497,COQ8B,RBMX2,DRD1,POU5F1,MIR185,SLC16A1,RBM38,UBA3,DCP2,CYP7A1,VDAC2,PRRC2A,AKAP8L,MRAS,ZMPSTE24,GUCY1B1,DGCR8,ZNF473,HOXB8,HLF,RAB5C,MIR505,NPC2,CDK20,RTKN,CSNK1A1,MIEF1,COIL,FEN1,TESK1,TLR9,IGF1R,MIR345,RAB6B,BRIX1,NPC1L1,MMACHC,ADRB2,NEUROD6,FOXD3,CEBPE,IFIH1,GRSF1,RND3,MIR330,RAB29,DR1,UBP1,SLC25A11,LSM2,SRPRB,EIF1AX,CDKN2AIP,MKKS,ZNF664,G3BP1,PRKCA,SCG5,JCHAIN,MIR137,NTRK2,ADK,RPL4,CCDC9B,TENT4A,RTL4,ORC6,HEBP1,ABCE1,RFC4,VIRMA,PCBP4,SNRPA,ADNP,IRF1,EP300,MIRLET7C,MIR142,IKBKB,RNASE6,PPP1CC,MIR572,TSG101,ZGLP1,XRCC5,EIF3J,MIR340,SAP18,ELF1,SPR,AGAP1,NUDT4,DNAJB6,HNRNPA2B1,CYB5A,TAF2,SUCLG2,SHPRH,THAP6,RAB1A,CBR3,VDR,EIF4H,SSRP1,MRPL16,ARL4A,RBM15B,FOLR1,PAIP2B,ILF2,HSPB1,NABP1,ELK3,EIF3E,MRPL11,RRM1,ISX,MIR302B,MACROH2A2,PPP5C,LSM14A,DNAJC27,MIR195,ARF6,NR1I2,TAF10,MIR204,GIMAP4,NOP53,IRF6,MIR301B,RABL3,KIT,CSRNP1,STAT6,EGR2,SLC6A3,AIFM1,KCNH1,SRP54,SOX21,FMO3,CXXC5,HMX1,YES1,HBA1,MIR769,SP4,PRPF4,EIF2D,CBFB,MIR448,NOL4,CAV1,RTF2,MIR188,CCDC47,UPF3B,RPL26L1,MIR24-1,BST2,ADORA1,MIR218-1,CCAR1,MIR939,POLDIP3,RAB11A,DKC1,STK26,SRSF2,FBXL19,ZMAT2,XPO5,RPL7L1,CCT2,GTF2H4,SMYD3,HBE1,SLC48A1,BAHD1,FOXN2,POLE3,SDS,H2AC13,TUBA1B,MIR33B,NOC4L,TLR8,XPO1,RERE,C1D,DDX46,MAB21L1,RBM18,MYRF,EIF2B2,CHCHD1,IFT22,MIR135B,NLRP9,DDX50,YTHDF2,SMNDC1,CNOT6,CWC15,MIR29C,ERCC3,ZBTB26,ATP1A3,RHOBTB3,THOC3,RPL6,MIR200A,ZNF596,MRPL20,TSPO2,SRSF7,CFAP20,RARS1,SP2,RPS17,KIAA0232,EXOSC3,MLF1,HSPA8,MEF2A,GFM1,FOXP4,CAMK1,STXBP1,OVOL1,MIR139,MAF1,POPDC3,PPARA,NME4,DDX1,ZNF581,TMSB4X,UBE2B,TAF7,CAMKV,DNASE1L1,NOTCH2,GTF2B,DCK,UBE2S,MIR133B,MVD,RNF40,ZNF436,POGK,ZCCHC17,MTDH,ATP5F1D,MIR454,OGG1,CIRBP,UGP2,DIS3L,SMAD4,SATB1,UBE2F,MIR31,FAU,MRPS26,PIAS1,MIR98,POLR1H,SCYL2,CREB3L4,TWNK,ATP1A2,PYGB,ORC5,MIR34B,FCF1,ZC3H14,MAPRE1,ZMYM4,SF3B6,CAMK2G,HDAC3,CHDH,ACAA2,POLD2,MIR1277,THOC2,SNRPB,MIR34A,GABPB1,ZNF322,RAN,AK2,UHMK1,MRPS7,ARF4,RPL37A,MIR1260B,RAB28,MIR105-1,CSRNP3,CYP4F22,HSD17B10,CHCHD2,LSM14B,DCLRE1C,SHMT1,APOBEC3F,ANXA7,RC3H2,POLR3B,APOBEC3D,CREBL2,SUGP1,TFRC,ZNF574,TUBG1,MBD3,CENPW,NKX3-1,RHOJ,EIF5A2,FOXI3,SUV39H1,JRKL,RLIG1,MRPS9,ATF1,HNRNPC,CMPK1,GSK3A,APOBEC3H,RPL22,GAPDH,PSMC4,HRAS,AOX1,NBN,STK3,RAB19,MIR342,RAB33B,RNASE9,TMEM199,TRIM23,MIR301A,STK16,YTHDF1,ARF1,ZBED1,ZNF821,THAP7,MCAT,REXO2,EIF1B,LBX1,CDC7,PIP4K2C,MCM4,RPL17,H1-6,IFT57,ABCC5,RPL29,NFKB1,MIR101-1,APOBEC3G,ERH,EPHB6,CGAS,GNAQ,RPL10A,PEG10,EIF4E2,ZBED4,MIR490,MTHFS,DNTTIP1,ATP8A1,ALYREF,RPL31,ALDH1A3,NIM1K,ZC3H11A,DDR1,ZBTB25,PSMC5,STRADB,LSM3,MIR30B,RBM34,CDK12,PRKX,SEPTIN6,ARL6,RIT2,SRSF4,OSBP,EMX2,P3H1,H2BC12,PAIP1,RAB37,IRGQ,H3C1,EEF1G,SAP30L,TOR2A,LARP4B,LDHB,SOX2,HSPA13,CSNK1G3,TERC,CPEB1,PAPOLA,RPS14,TRA2A,HINFP,IRAK4,RPL35,INSM2,MAP3K3,SRP14,HELT,SNRPG,CYFIP2,KRR1,MIR338,PGR,RP2,BRD3,MIR378A,ATL1,RAD21,ACTL6A,GUK1,CDK5,OSR2,KARS1,TXNRD3,CYP2D6,GTF2A1,MIR1271,ELAVL2,MYBL2,SDHC,UBE2K,MX1,PCGF2,RBPJ,KATNAL1,SHOC1,ZBTB5,H2BC11,SPTBN1,PIWIL1,TYW5,DRGX,ZNF250,MIR107,ZNF267,MIR519D,HNRNPL,RAB32,CASC3,ABCG2,H2AC25,STYK1,UBE2M,MAGOHB,RFXAP,MIR361,WRAP53,ZNF7,RP9,UCK2,MIR423,ZCRB1,CDK7,ATP6V1A,MATR3,IRF9,ZFP1,STK38L,CYP4F8,MIR503,DIRAS1,MIR212,DDX39A,STAU1,MIR206,MIR190B,MIR106B,TDRD7,DNM2,TESK2,EXOSC1,DNAJC1,SEPHS2,CREBBP,MIR136,RDM1,METTL14,MRPS18A,MIR298,ZNF207,KLF10,PIWIL3,TMEM97,CYP4V2,TAL2,GDI2,BACH1,EIF4E,ELK1,ILVBL,TNF,FAAP100,H2AJ,PRPSAP1,MECP2,FN3KRP,MTARC2,CSTB,ACCS,ZCCHC12,SOX9,HP1BP3,TEF,BVES,RPL3,MIR30A,SCG3,MIR573,EHHADH,MIR339,ACOX1,RPS2,P2RY4,SMAD9,MRPS21,NKAP,RPS26,TRMT10B,RPA2,TOR3A,GPBP1L1,WDR6,STAR,PCCB,RPS5,SMAD2,RPS23,PIK3CA,MET,MIR198,DDX4,RFC2,KLF4,MTPN,DHRS11,NCBP2,RAB39B,CSNK1E,AATF,GDPGP1,KLF3,NOP9,MIR149,ARL5B,ZNF287,GTF2F1,IRF7,ACTN4,TNIK,RBBP8,MIR143,ACTR3B,UCP2,UTP25,RAP2A,UBE2H,MIR106A,ZBTB33,GPHN,PIP5K1A,RPL27A,RALA,GNAO1,MIRLET7B,ALKBH2,MIR492,PAX6,MAP1S,NTPCR,ZNF593,NOSIP,SEC61B,MIR552,OTUD7B,STAT1,MAGOH,HSP90AA1,H2BC1,RAB3D,POLR2D,MAP3K12,ERAS,RIT1,SERPINH1,ALKBH5,PRKRA,MIR148A,PRDX1,MRPL9,STK11,DHX15,RNASET2 |
| 3.054e-02 | -3.49 | Synthesis of very long-chain fatty acyl-CoAs | REACTOME pathways | R-HSA-75876 | 28 | 14 | 10285 | 3229 |
ELOVL4,HACD1,ELOVL6,ACSL4,HACD4,ELOVL3,TECR,HACD2,MIR639,ELOVL7,HSD17B3,HACD3,ELOVL1,PPT1 |
| 3.054e-02 | -3.49 | Insulin processing | REACTOME pathways | R-HSA-264876 | 28 | 14 | 10285 | 3229 |
SLC30A5,ERO1A,RAB27A,EXOC8,SLC30A7,PCSK2,EXOC2,VAMP2,EXOC1,CPE,EXOC5,EXOC3,CLTRN,STX1A |
| 3.054e-02 | -3.49 | FGFR2 alternative splicing | REACTOME pathways | R-HSA-6803529 | 28 | 14 | 10285 | 3229 |
HNRNPF,POLR2D,POLR2L,HNRNPA1,POLR2I,GTF2F1,POLR2B,NCBP2,TIA1,POLR2F,GTF2F2,POLR2G,POLR2C,RBFOX2 |
| 3.054e-02 | -3.49 | regulation of B cell activation | biological process | GO:0050864 | 128 | 48 | 18204 | 5365 |
CTLA4,CD81,INHA,IL2,IL4,NDFIP1,TLR9,CD38,TNFSF13,XBP1,EXOSC3,CHRNB2,IL7,MEF2C,BAD,TBC1D10C,CD28,CDKN1A,TIRAP,TICAM1,TYROBP,HMCES,IL5,MAD2L2,TLR4,MZB1,PELI1,STAT6,FCGR2B,CD40,BCL6,FOXP3,MIF,SYK,SASH3,IL2RG,IL13,TFRC,IL6,KMT5B,SFRP1,IL21,SHLD1,TNFAIP3,IL10,MMP14,MIR185,SLC39A10 |
| 3.058e-02 | -3.49 | ZNF185 (zinc finger protein 185 with LIM domain) | protein interactions | 7739 | 60 | 24 | 19454 | 5460 |
NRSN1,ETNK2,APEX1,ESR2,EMILIN1,MYC,LMO2,CIAO1,CUL3,COPS5,HDAC6,BICD2,AGPAT1,DDX39B,RPA3,PML,HSPA8,UBE3A,HSPA5,ATG16L1,SOX2,CFTR,STX17,CCR1 |
| 3.058e-02 | -3.49 | MAD2L1BP (MAD2L1 binding protein) | protein interactions | 9587 | 60 | 24 | 19454 | 5460 |
LBR,EEF1A1,FNDC8,TP53,MAD2L1BP,PTPN22,CTSA,NDUFS6,PYM1,IGSF21,PTN,ZBTB14,API5,CCNB1,ANAPC4,RIT1,POLR1B,INPP5K,LRIF1,MAD2L1,CDC20,MAD2L2,NMI,SPPL3 |
| 3.058e-02 | -3.49 | SIK1 (salt inducible kinase 1) | protein interactions | 150094 | 60 | 24 | 19454 | 5460 |
NCKAP1,VIRMA,FBXO22,HDAC5,APPBP2,RPL3,GLUL,SIN3A,YWHAB,STK11,TAB2,YWHAZ,GINS4,ATP5PO,APOBEC3A,PPP2R1A,YWHAG,MX1,XPO1,YWHAH,CRTC2,EEF1A1,SUPT5H,AKT1 |
| 3.058e-02 | -3.49 | TSEN15 (tRNA splicing endonuclease subunit 15) | protein interactions | 116461 | 60 | 24 | 19454 | 5460 |
PSMC3,POLR2G,LMO4,DDIT4L,ENKD1,PAEP,AIF1L,KRAS,EXOSC4,CLP1,PHOSPHO2,VCPIP1,MSMB,TSEN54,TSEN34,GORASP2,LMO2,LRIF1,RANGRF,AASDHPPT,HNRNPL,ZMAT2,PRR3,DECR2 |
| 3.060e-02 | -3.49 | RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway | WikiPathways | WP2018 | 55 | 27 | 5310 | 1910 |
PIK3R1,TRAF6,STAT1,MITF,IKBKB,CDC42,TRAF2,SQSTM1,CTSK,FOS,AKT1,TAB2,ICAM1,MAP2K1,MAP2K6,SYK,TRAF1,PAPSS2,ACP5,NFKB1,TAB1,NFKBIA,JUN,AKT2,CBL,PIK3R2,SRC |
| 3.061e-02 | -3.49 | MIR9-3 (microRNA 9-3) | protein interactions | 407051 | 66 | 26 | 19454 | 5460 |
RTCB,SF3B1,HNRNPH2,HNRNPA2B1,MARS1,HNRNPK,HNRNPF,TRA2B,HNRNPA0,STRBP,RBFOX2,HNRNPH3,RARS1,P3H1,EIF2AK2,SYNCRIP,MATR3,HNRNPL,FAM98A,NONO,HNRNPA1,KARS1,APOBEC3B,IGF2BP1,DDX1,CRTAP |
| 3.061e-02 | -3.49 | F2 (coagulation factor II, thrombin) | protein interactions | 2147 | 66 | 26 | 19454 | 5460 |
SERPIND1,SERPINB6,DDIT3,SERPINA5,NUPR1,CCR1,CHAMP1,IGFBP3,AKR7A2,RAF1,AANAT,CGAS,FBXO22,THBD,ALB,F10,SERPINC1,AGPAT1,GGCX,UBE2H,F9,SPP1,CAMP,ST13,F2,PROS1 |
| 3.062e-02 | -3.49 | soft_tissue-blood_vessel-perivascular_epithelioid_cell_tumour_(PEComa) | COSMIC cancer mutations | soft_tissue-blood_vessel-perivascular_epithelioid_cell_tumour_(PEComa) | 12 | 7 | 16828 | 4835 |
TP53,KIT,GNA11,KRAS,AKT1,PIK3CA,GNAQ |
| 3.062e-02 | -3.49 | lymphoplasmacytic_lymphoma | COSMIC cancer mutations | lymphoplasmacytic_lymphoma | 12 | 7 | 16828 | 4835 |
MYD88,EZH2,JAK2,PTEN,HRAS,CD79B,KRAS |
| 3.062e-02 | -3.49 | central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour | 12 | 7 | 16828 | 4835 |
MET,KRAS,IDH2,AKT1,IDH1,PIK3CA,GNAQ |
| 3.062e-02 | -3.49 | bone-chordoma | COSMIC cancer mutations | bone-chordoma | 12 | 7 | 16828 | 4835 |
IDH1,TP53,KIT,SMARCB1,PIK3CA,SS18,TERT |
| 3.062e-02 | -3.49 | skin-abdomen-malignant_melanoma-nodular | COSMIC cancer mutations | skin-abdomen-malignant_melanoma-nodular | 12 | 7 | 16828 | 4835 |
GNA11,KIT,HRAS,KRAS,CTNNB1,GNAQ,PTEN |
| 3.062e-02 | -3.49 | perivascular_epithelioid_cell_tumour_(PEComa) | COSMIC cancer mutations | perivascular_epithelioid_cell_tumour_(PEComa) | 12 | 7 | 16828 | 4835 |
TP53,GNA11,KIT,KRAS,AKT1,PIK3CA,GNAQ |
| 3.062e-02 | -3.49 | central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour | COSMIC cancer mutations | central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour | 12 | 7 | 16828 | 4835 |
MET,KRAS,IDH2,AKT1,IDH1,PIK3CA,GNAQ |
| 3.062e-02 | -3.49 | skin-benign_melanocytic_nevus | COSMIC cancer mutations | skin-benign_melanocytic_nevus | 12 | 7 | 16828 | 4835 |
KRAS,HRAS,GNA11,TP53,GNAQ,PIK3CA,TERT |
| 3.062e-02 | -3.49 | blastoma | COSMIC cancer mutations | blastoma | 12 | 7 | 16828 | 4835 |
ETV6,TP53,KIT,KRAS,CTNNB1,DICER1,PIK3CA |
| 3.063e-02 | -3.49 | IFNAR1 (interferon alpha and beta receptor subunit 1) | protein interactions | 3454 | 63 | 25 | 19454 | 5460 |
JAK1,TRIM10,LRP10,BMPR1A,HSPD1,HNRNPK,KIT,IFNGR1,SHMT1,STAT6,CRKL,FGFR1,CTLA4,AP2M1,LRP12,STX6,NDFIP1,STAT2,PTPN11,PIK3R1,IFNA2,YWHAB,PAXX,FBXW11,IFNB1 |
| 3.063e-02 | -3.49 | MTMR3 (myotubularin related protein 3) | protein interactions | 8897 | 63 | 25 | 19454 | 5460 |
HDAC11,STN1,DNAJC10,YWHAZ,ZDHHC15,FIS1,YWHAB,TOP3B,CUL3,EDEM1,YWHAH,GTF3C4,YWHAG,TULP3,AIPL1,EYA3,MAPK1IP1L,EGLN3,VIRMA,SSBP1,THOC2,SLU7,PNO1,IL10,DERL1 |
| 3.063e-02 | -3.49 | FADS2 (fatty acid desaturase 2) | protein interactions | 9415 | 63 | 25 | 19454 | 5460 |
PSEN1,PDE2A,SLC6A8,TGFBR2,HSPA8,DERL1,GPBP1L1,RPN1,SEC62,SOX2,DNAJC25,OTULINL,TMPO,HSD17B11,ZNF655,SEC61B,CCNF,ATXN1L,RNF139,ATP1B3,AR,MYC,GRSF1,CUL3,RAB5C |
| 3.063e-02 | -3.49 | UBL7 (ubiquitin like 7) | protein interactions | 84993 | 63 | 25 | 19454 | 5460 |
UBB,TTC9C,PTEN,CD4,CLIC2,UBE2D1,PPM1B,FBXW11,HDAC6,CSK,WWP2,LRRC73,HSPA5,AHCYL1,NEDD8,UCHL3,IDH1,ZYX,PSME1,ZRANB2,SH3GLB1,DCUN1D5,RAD23B,PIR,KDELR1 |
| 3.063e-02 | -3.49 | ARHGEF40 (Rho guanine nucleotide exchange factor 40) | protein interactions | 55701 | 63 | 25 | 19454 | 5460 |
TNKS2,AZGP1,FTL,CHCHD2,SQSTM1,CXCR4,CDC42,CD2BP2,SOX2,LGR4,ATG16L1,TOP3B,RAF1,H2BW1,VIRMA,TAC1,RAC2,SPIN3,TNKS,LMBR1L,DCAF4,P2RY10,PPIL4,MYC,DYRK1B |
| 3.063e-02 | -3.49 | GPBP1 (GC-rich promoter binding protein 1) | protein interactions | 65056 | 63 | 25 | 19454 | 5460 |
ZC3H7A,DNAL4,EP300,CNOT7,DUSP14,H1-5,TPD52,FAM161A,TNRC6C,DENND2D,CRYAB,PSMB1,RPS20,PLEKHF2,EGLN3,PRPF18,FNDC11,MOV10,SFN,YWHAG,YWHAH,YWHAZ,BICD2,HNRNPD,SLX1A |
| 3.063e-02 | -3.49 | CHPT1 (choline phosphotransferase 1) | protein interactions | 56994 | 63 | 25 | 19454 | 5460 |
GINM1,TP53,TMEM59,BPGM,CD1B,SLC15A1,SLC5A6,TSPAN15,BSCL2,SLC22A6,PDCD1,CDH13,LRRC8B,MICB,RAB2A,GPR17,OPRM1,PGAM1,CCR6,LAMP3,APLNR,OPRL1,TLCD4,CCNF,SLC1A1 |
| 3.063e-02 | -3.49 | NRBP2 (nuclear receptor binding protein 2) | protein interactions | 340371 | 63 | 25 | 19454 | 5460 |
RPS15,CA10,NDUFA4,CLPB,TMEM165,YTHDF2,MRPL10,TSC22D3,POLR2B,LANCL1,PSMB4,RAP1B,SDF2L1,AK2,TUBG1,PSMD14,SNRNP70,HAX1,AKAP8L,DNAJB6,SERPINH1,ISYNA1,XPO1,MLF2,ELOC |
| 3.063e-02 | -3.49 | GDF9 (growth differentiation factor 9) | protein interactions | 2661 | 63 | 25 | 19454 | 5460 |
SAT1,RAB27A,BMPR1A,ORAI2,CDKN2C,SNRPG,SMN1,KDM1A,CDKN1A,SERPINB9,H1-5,CRELD1,ANXA7,BMPR2,S100A8,MOB4,PRKRA,DNM2,RSRC1,PAFAH1B3,GADD45G,BMPR1B,LSM3,MPHOSPH6,FXYD6 |
| 3.063e-02 | -3.49 | PRDM10 (PR/SET domain 10) | protein interactions | 56980 | 63 | 25 | 19454 | 5460 |
RPL7A,ZCCHC10,H2AC4,H1-1,SDC4,KRR1,RPS3,RPS9,PRKRA,SNRNP40,RPS16,RPS10,VIRMA,ESR2,WDR77,H1-3,CBX3,SDC2,RPLP0,PPAN,RPL31,BAP1,RPL23A,H1-6,SRSF4 |
| 3.068e-02 | -3.48 | human chrXq12 | chromosome location | human chrXq12 | 9 | 5 | 26134 | 5823 |
OPHN1,MIR223,EDA2R,AR,MSN |
| 3.069e-02 | -3.48 | thymoma | COSMIC cancer mutations | thymoma | 17 | 9 | 16828 | 4835 |
TP53,KRAS,KIT,HRAS,FBXW7,AKT1,PIK3CA,GNAQ,PTEN |
| 3.069e-02 | -3.48 | thymus-thymoma | COSMIC cancer mutations | thymus-thymoma | 17 | 9 | 16828 | 4835 |
FBXW7,AKT1,TP53,HRAS,KIT,KRAS,PTEN,PIK3CA,GNAQ |
| 3.069e-02 | -3.48 | small_intestine-jejunum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-jejunum-carcinoma-adenocarcinoma | 17 | 9 | 16828 | 4835 |
PTPN11,FBXW7,CTNNB1,KRAS,TP53,SMARCB1,SMAD4,STK11,PIK3CA |
| 3.069e-02 | -3.48 | NS-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | NS-carcinoma-squamous_cell_carcinoma | 17 | 9 | 16828 | 4835 |
IDH1,AKT1,TP53,KRAS,CTNNB1,KIT,PTEN,PIK3CA,MAP2K1 |
| 3.069e-02 | -3.48 | liver-other-adenoma | COSMIC cancer mutations | liver-other-adenoma | 17 | 9 | 16828 | 4835 |
IL6ST,HRAS,KRAS,CTNNB1,TP53,JAK1,JAK2,TERT,PIK3CA |
| 3.069e-02 | -3.48 | bone-sacrum-chordoma | COSMIC cancer mutations | bone-sacrum-chordoma | 17 | 9 | 16828 | 4835 |
HRAS,KIT,CTNNB1,KRAS,TP53,JAK2,PIK3CA,SMARCB1,PTEN |
| 3.069e-02 | -3.48 | jejunum | COSMIC cancer mutations | jejunum | 17 | 9 | 16828 | 4835 |
FBXW7,PTPN11,TP53,KRAS,CTNNB1,SMAD4,SMARCB1,PIK3CA,STK11 |
| 3.071e-02 | -3.48 | ZC3H10 (zinc finger CCCH-type containing 10) | protein interactions | 84872 | 198 | 68 | 19454 | 5460 |
NKRF,RPL3,KRAS,PAK1IP1,LASP1,RPS13,SRSF4,RPL28,RBM38,MLLT6,MAK16,MSX2,RPL15,RBM34,OTX2,RPL18,RPL8,SPMIP9,BOLL,RPL32,CEBPG,CAND1,DKC1,SURF6,DDX50,MIR143,SPATS2L,MPHOSPH10,ACTMAP,SNRPA,FAM168B,SPECC1L,APPBP2,NPM3,DGCR8,NOP53,STAU1,BRIX1,AATF,RBFOX2,KRTAP8-1,APOBEC3C,PICALM,RPL26L1,RPLP0,ZNF770,PELP1,ZNF22,TRMT6,RPL37A,PRKRA,UBE2I,ZCCHC7,RPL13A,RPF1,RPL7L1,SLC25A31,RSL24D1,RPL22,NFYA,RPF2,CUL3,RPL7A,ZNF668,FTSJ3,NSA2,H1-1,CDKN2AIP |
| 3.073e-02 | -3.48 | ARL15 (ADP ribosylation factor like GTPase 15) | protein interactions | 54622 | 109 | 40 | 19454 | 5460 |
AKAP12,UBE2K,PTN,TFG,SNAP23,PICK1,SLC39A7,JAK1,GHITM,NHERF1,GOLGA5,PDE6D,OXSR1,SLC25A20,ARHGAP1,MARCKSL1,CTDSP2,HCST,SNX3,B4GALT3,HNRNPL,FUNDC2,IREB2,FERMT2,NECTIN2,CCDC90B,RPL8,CDC42EP3,CDCA3,FAM83B,ADD1,SERINC1,WDR20,CRMP1,SLC38A1,NAB2,GAPDH,TENM3,CNNM4,PPFIBP1 |
| 3.083e-02 | -3.48 | ATP transmembrane transporter activity | molecular function | GO:0005347 | 14 | 8 | 18094 | 5411 |
SLC25A31,SLC25A42,SLC25A5,SLC25A24,ANKH,SLC25A4,SLC25A23,SLC25A17 |
| 3.083e-02 | -3.48 | U6 snRNA binding | molecular function | GO:0017070 | 14 | 8 | 18094 | 5411 |
PRPF4,LSM8,LSM4,RBM22,SART3,DDX39B,LSM3,LSM2 |
| 3.084e-02 | -3.48 | SAM-dependent_MTases_sf | interpro domains | IPR029063 | 123 | 46 | 18521 | 5414 |
COMT,PRMT5,CSKMT,GNMT,METTL6,PRMT6,METTL2A,GAMT,METTL21A,METTL18,COMTD1,CMTR1,SRM,GSTCD,INMT,CMTR2,TMT1B,HENMT1,METTL26,TRMT1L,FTSJ1,PRMT2,EEF2KMT,METTL25B,ETFBKMT,EEF1AKMT3,TRMT5,METTL15,PCMTD2,METTL14,PCMTD1,BUD23,FTSJ3,ASMT,MRM2,TFB1M,VCPKMT,TRMT11,TMT1A,NTMT1,TRMT61A,METTL22,LRTOMT,MEPCE,HNMT,LCMT1 |
| 3.084e-02 | -3.48 | U1 snRNP | cellular component | GO:0005685 | 22 | 11 | 19108 | 5553 |
SNRPD2,SNRPA,SNRPD1,SNRPB2,SNRPB,SNRNP70,SNRPD3,LUC7L3,SNRPE,SNRPN,SNRPG |
| 3.084e-02 | -3.48 | telomerase holoenzyme complex | cellular component | GO:0005697 | 22 | 11 | 19108 | 5553 |
TERC,NHP2,DKC1,SNRPB,SNRPD3,WRAP53,HNRNPC,TERT,SMG5,PTGES3,SNRPE |
| 3.088e-02 | -3.48 | NAT9 (N-acetyltransferase 9 (putative)) | protein interactions | 26151 | 20 | 10 | 19454 | 5460 |
ERG28,SMAD1,NUDT18,BCL7B,ENO2,EEF1E1,CRMP1,NAT9,PALS2,FBXO22 |
| 3.088e-02 | -3.48 | NUDT10 (nudix hydrolase 10) | protein interactions | 170685 | 20 | 10 | 19454 | 5460 |
ZMYM6,DUSP19,TRIM8,SNAPC5,RNASEH2C,NUDT4,DUSP9,NUDT3,DDRGK1,HSPA8 |
| 3.088e-02 | -3.48 | PITPNC1 (phosphatidylinositol transfer protein cytoplasmic 1) | protein interactions | 26207 | 20 | 10 | 19454 | 5460 |
SCAMP5,SYP,SMPD2,YWHAZ,RIGI,YWHAB,KATNAL1,AGTRAP,YWHAH,YWHAG |
| 3.088e-02 | -3.48 | IL1RL1 (interleukin 1 receptor like 1) | protein interactions | 9173 | 20 | 10 | 19454 | 5460 |
TRAF6,CLEC12B,SLC38A1,IRAK4,MYD88,HRAS,TMED1,CLEC7A,TIRAP,TSPAN18 |
| 3.088e-02 | -3.48 | IFNG (interferon gamma) | protein interactions | 3458 | 20 | 10 | 19454 | 5460 |
PDIA3,ACTA2,IFNGR1,TNF,ACTB,DCAF4,PDF,ICAM1,STAT6,IFNG |
| 3.088e-02 | -3.48 | Kif1c (kinesin family member 1C) | protein interactions | 16562 | 20 | 10 | 19454 | 5460 |
KIF1C,EIF4A3,SUB1,ALYREF,SSBP1,ARF1,GAPDH,CHTOP,THRAP3,HNRNPD |
| 3.088e-02 | -3.48 | SLC23A2 (solute carrier family 23 member 2) | protein interactions | 9962 | 20 | 10 | 19454 | 5460 |
SLC38A7,HRAS,JAGN1,SLC41A1,H2BC9,COA1,NSG1,TMEM60,KRAS,VIRMA |
| 3.088e-02 | -3.48 | DOHH (deoxyhypusine hydroxylase) | protein interactions | 83475 | 20 | 10 | 19454 | 5460 |
SCNM1,BAG3,TOM1,FN3KRP,EIF5A2,STARD7,KRAS,RIT1,EIF4B,IDE |
| 3.088e-02 | -3.48 | C2orf73 (chromosome 2 open reading frame 73) | protein interactions | 129852 | 20 | 10 | 19454 | 5460 |
ATG3,DHX16,FCHSD2,HSPB1,SH3BP4,MGME1,BABAM1,NEK9,CREB1,GALE |
| 3.088e-02 | -3.48 | SZRD1 (SUZ RNA binding domain containing 1) | protein interactions | 26099 | 20 | 10 | 19454 | 5460 |
TOM1L2,NT5C2,ENO1,MOV10,MYC,EHD4,SRP14,MTMR2,CCAR1,P3H1 |
| 3.088e-02 | -3.48 | NCAM2 (neural cell adhesion molecule 2) | protein interactions | 4685 | 20 | 10 | 19454 | 5460 |
YWHAG,YWHAH,HNRNPC,SCG3,RSPH1,YWHAB,ESR2,YWHAZ,PRNP,HNRNPL |
| 3.088e-02 | -3.48 | RGS4 (regulator of G protein signaling 4) | protein interactions | 5999 | 20 | 10 | 19454 | 5460 |
SQSTM1,PLCB1,MTHFS,GNAO1,PREPL,GNAI2,GNAQ,KRIT1,GABBR1,PAK2 |
| 3.088e-02 | -3.48 | SERPINA4 (serpin family A member 4) | protein interactions | 5267 | 20 | 10 | 19454 | 5460 |
CTBP1,TAB1,FKBP14,GADD45G,TNFRSF14,YAE1,ILK,FDFT1,CTSD,CFTR |
| 3.088e-02 | -3.48 | LBP (lipopolysaccharide binding protein) | protein interactions | 3929 | 20 | 10 | 19454 | 5460 |
CAMP,PRDX4,HSPB1,SMAD3,CSK,CD14,SOX2,FTH1,TRA2A,PSMA3 |
| 3.088e-02 | -3.48 | Trappc8 (trafficking protein particle complex 8) | protein interactions | 75964 | 20 | 10 | 19454 | 5460 |
TRAPPC3,NEK9,TRAPPC1,TRAPPC6A,SERINC3,TRAPPC13,CCAR1,DROSHA,TRAPPC2L,CIRBP |
| 3.088e-02 | -3.48 | ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3) | protein interactions | 6487 | 20 | 10 | 19454 | 5460 |
APEX1,ZBTB5,SPCS1,TTR,HNRNPL,SEC11A,GALNT12,SCAMP2,SERPINB9,RPL8 |
| 3.088e-02 | -3.48 | ENC1 (ectodermal-neural cortex 1) | protein interactions | 8507 | 20 | 10 | 19454 | 5460 |
SQSTM1,RB1,NUDCD3,CUL3,KLHL25,KLHL9,HSP90AA1,NFE2L2,HNRNPL,ENC1 |
| 3.088e-02 | -3.48 | ZNF385A (zinc finger protein 385A) | protein interactions | 25946 | 20 | 10 | 19454 | 5460 |
RIGI,MIR1-1,MIR155,PRNP,MIR9-1,HNRNPL,MIR9-3,MIR34C,MIR9-2,MYC |
| 3.088e-02 | -3.48 | THAP6 (THAP domain containing 6) | protein interactions | 152815 | 20 | 10 | 19454 | 5460 |
ING5,LMO2,PSMB1,ZNF655,TNPO2,PICK1,NTAQ1,MAD2L2,AP1M1,THAP6 |
| 3.088e-02 | -3.48 | CLEC5A (C-type lectin domain containing 5A) | protein interactions | 23601 | 20 | 10 | 19454 | 5460 |
PTRH2,SAMM50,EMC8,REEP6,MEPCE,DAD1,TYROBP,TMBIM6,YIF1A,CHCHD6 |
| 3.088e-02 | -3.48 | GNG3 (G protein subunit gamma 3) | protein interactions | 2785 | 20 | 10 | 19454 | 5460 |
GNAO1,NTAQ1,GNA11,GNB3,PDCL,GNB4,GNAI2,GNAQ,GNAZ,GNB1 |
| 3.088e-02 | -3.48 | FBXL3 (F-box and leucine rich repeat protein 3) | protein interactions | 26224 | 20 | 10 | 19454 | 5460 |
CRY1,PICK1,BTG2,TCAP,TTC9C,CAND1,SKP1,BTG1,HSP90AA1,SLC25A31 |
| 3.089e-02 | -3.48 | human chr22q13.1 | chromosome location | human chr22q13.1 | 82 | 26 | 26134 | 5823 |
NOL12,APOBEC3B,TMEM184B,MIEF1,RPL3,GRAP2,CBX7,SYNGR1,JOSD1,ELFN2,APOBEC3D,CSNK1E,APOBEC3C,ATF4,TOMM22,CYTH4,DNAL4,APOBEC3F,APOBEC3A,TAB1,APOBEC3G,APOBEC3H,PICK1,RAC2,POLR2F,GTPBP1 |
| 3.089e-02 | -3.48 | myeloid cell activation involved in immune response | biological process | GO:0002275 | 66 | 27 | 18204 | 5365 |
SYK,SNAP23,CCL3,VAMP8,MYD88,KIT,CBL,IFI35,LILRA2,PIK3CG,PYCARD,LAT2,VAMP2,TICAM1,TYROBP,TNF,PTGDS,NMI,FCER1G,KARS1,IFNG,MRGPRX2,CPLX2,PRKCE,CX3CR1,CHGA,VAMP7 |
| 3.089e-02 | -3.48 | GTF3C5 (general transcription factor IIIC subunit 5) | protein interactions | 9328 | 150 | 53 | 19454 | 5460 |
TAF10,MOB3C,RBPJ,PNMA2,EZH2,CDK8,SMAD1,SOX2,MDC1,PTGES3,GTF3C3,H3C1,KRAS,SNRNP70,DDRGK1,HDAC6,CSNK2A1,XPO1,IFI16,UBXN6,MDFI,ANKRA2,EGLN3,TCF21,TOP1,RPS16,PHB1,COQ8A,RPA2,FOXS1,CDK7,GTF3C4,COIL,FBXW7,UFL1,RNF113A,EP300,RPA3,BAP1,DVL2,RIT1,UBE2H,TXNIP,CUL3,SUB1,MYC,MAD2L2,TUBB,PTEN,CSNK2B,PPM1M,CIB2,CCNF |
| 3.089e-02 | -3.48 | FBXW8 (F-box and WD repeat domain containing 8) | protein interactions | 26259 | 150 | 53 | 19454 | 5460 |
MRPL52,MRFAP1,MMP9,LAMB2,PSMA1,G3BP1,KPNA2,ZNF263,CCT5,TP53,SPRED2,TTC9C,TCP1,NCBP2,ERLIN1,TMPO,CCT7,PSMD3,PFDN5,XPO1,CBR4,EIF5A2,ZDHHC15,FAM222A,DLAT,SNX33,EP300,UBE2D3,SKP1,G3BP2,UTP23,CCND1,FHOD3,CNP,RPL26L1,MYL6,NFKBIA,FBLN5,ATP5F1B,SNRNP40,RBBP4,PSMB6,PDCD5,MYC,CUL2,COX11,MRPS16,CCT2,SPMAP1,STK11,HSP90AA1,PFDN6,TRIB1 |
| 3.090e-02 | -3.48 | ASIC4 (acid sensing ion channel subunit family member 4) | protein interactions | 55515 | 131 | 47 | 19454 | 5460 |
NETO2,B3GNT2,CCDC47,DIPK1A,MAP2K3,DDX39A,OTX2,POMT2,ADCY3,ITGB5,CHST10,GALNT12,BSCL2,ERLEC1,TMBIM6,OSBPL8,TMEM30A,ITGA6,CHID1,ASIC1,TMEM231,CLSTN3,HYAL2,CFTR,GLRB,COMMD3,MET,TMEM106B,TMX2,CYB5D2,ITGA2,RLIM,COMMD2,TAPBP,SKP1,ZDHHC17,GABRB3,HSPA14,HMOX2,HFE,TMEM106C,FAM210A,ODR4,GGT7,OAF,LRP12,NLGN2 |
| 3.090e-02 | -3.48 | EPB41 (erythrocyte membrane protein band 4.1) | protein interactions | 2035 | 131 | 47 | 19454 | 5460 |
TAGLN2,ESR2,OPTN,CCNF,EIF3G,CA2,RAB11A,WDR3,UFL1,KRT222,PRKCB,HSPA8,CRYAB,DRD3,TMOD1,UBE2M,SPTBN1,SF3A1,SEC62,HNRNPL,ARF6,SPTAN1,STX6,CAV1,MACROD1,HRAS,RAB35,SMAD3,C2CD2,RHOG,MED4,C2CD2L,YWHAB,CALR,ZCCHC10,YWHAG,YWHAH,KRAS,KPNA2,FKBP2,FLOT1,DLG1,ABCE1,SEC14L1,NECAP1,CASK,TP53 |
| 3.093e-02 | -3.48 | Regulation of thyroid hormone activity | REACTOME pathways | R-HSA-350864 | 3 | 3 | 10285 | 3229 |
DIO3,DIO1,DIO2 |
| 3.093e-02 | -3.48 | SMAD4 MH2 Domain Mutants in Cancer | REACTOME pathways | R-HSA-3311021 | 3 | 3 | 10285 | 3229 |
SMAD4,SMAD2,SMAD3 |
| 3.093e-02 | -3.48 | FMO oxidises nucleophiles | REACTOME pathways | R-HSA-217271 | 3 | 3 | 10285 | 3229 |
FMO3,FMO2,FMO1 |
| 3.093e-02 | -3.48 | MyD88 deficiency (TLR5) | REACTOME pathways | R-HSA-5602680 | 3 | 3 | 10285 | 3229 |
IRAK4,MYD88,TLR5 |
| 3.093e-02 | -3.48 | Oligomerization of connexins into connexons | REACTOME pathways | R-HSA-190704 | 3 | 3 | 10285 | 3229 |
GJA1,GJB1,GJB2 |
| 3.093e-02 | -3.48 | Loss of Function of SMAD4 in Cancer | REACTOME pathways | R-HSA-3304347 | 3 | 3 | 10285 | 3229 |
SMAD3,SMAD2,SMAD4 |
| 3.093e-02 | -3.48 | Rhesus glycoproteins mediate ammonium transport. | REACTOME pathways | R-HSA-444411 | 3 | 3 | 10285 | 3229 |
RHCG,RHBG,RHAG |
| 3.093e-02 | -3.48 | Transport of connexins along the secretory pathway | REACTOME pathways | R-HSA-190827 | 3 | 3 | 10285 | 3229 |
GJB2,GJB1,GJA1 |
| 3.093e-02 | -3.48 | Formation of the active cofactor, UDP-glucuronate | REACTOME pathways | R-HSA-173599 | 3 | 3 | 10285 | 3229 |
SLC35D1,UGP2,UGDH |
| 3.102e-02 | -3.47 | CDK5RAP2 (CDK5 regulatory subunit associated protein 2) | protein interactions | 55755 | 182 | 63 | 19454 | 5460 |
CDK5,ERG28,PABPC1,RIGI,PRPS1,FBXO25,TRIM37,FGL2,TBK1,CSTPP1,TBC1D4,CDK5R1,POLR2C,CAPZA2,NEFL,VPS33A,KRT8,MAGED2,TMPO,EGLN3,LRRC61,MIF,PRNP,ARF6,MZT2B,INSYN1,NDC80,RAB5C,TSNAX,DNAJC7,SSX2IP,HAX1,TUBG1,DDX5,H2BC12,SQSTM1,TXNL1,TRIM52,EEF1G,PTN,BORCS6,CCND1,LPXN,ATG16L1,TRIM36,PRKCA,RPA2,LMNA,ANAPC2,LURAP1,S100A6,VIRMA,RPGRIP1L,DYNLL1,RBBP4,SSH3,PCBD1,PRKACB,MLF1,MAPRE1,MAGEH1,CRMP1,PTTG1 |
| 3.106e-02 | -3.47 | OCLN (occludin) | protein interactions | 100506658 | 495 | 158 | 19454 | 5460 |
RND3,STK16,HGS,VAMP2,TMEM182,RPN1,RAB4A,AQP3,TULP3,IFNGR1,CSNK1E,RAB8B,FLOT1,SAR1B,KRAS,EPHA4,GJB1,SEMA4C,MYO1B,EFNB1,TMEM87A,TMT1A,RASSF8,RHOG,PPFIBP1,CTNNB1,FATE1,LAMP2,ATG9A,PIK3R1,RAB5C,PCNX1,DIRAS3,RAMP3,OCRL,SPTAN1,RHOH,GJA1,C2CD4C,ARL11,RAB35,WDR6,TNIK,CSNK1A1,ZER1,RND2,CLDN4,USP6NL,BET1,NOTCH2,STX7,ARL6,RAB5A,EMP3,MIA2,SLC38A1,LAMTOR1,RHOB,HBEGF,NIBAN2,SCN3B,RAB11A,PKP4,ESR2,SYNE4,FAM83B,SEC61B,LMBR1L,CASK,EXOC3,PLAAT3,SIGLECL1,CTLA4,UBIAD1,SNAP29,COMTD1,PREB,SLC6A8,CTNND1,ADD2,AKAP12,TNFSF8,RAB3B,TGFBR2,CD1B,SRPRB,SEPTIN7,NTRK2,SNAP23,LRRN4CL,PALM2AKAP2,DLG1,CLEC7A,ATP2B4,STYK1,SMAD4,TIAM1,NOS1AP,LAMP3,CSNK2A1,DPP4,MICB,LMAN1,SLC38A2,STX6,DUOXA2,CAV1,ARF6,FCHO2,DLGAP4,ADD1,SLC39A10,CDCA3,RAC2,HRAS,EHBP1,PRKCA,ARL15,JUP,PICALM,GOLGA5,SLC12A2,SIPA1L1,CDC42,PDE8A,SPTBN1,UBA52,ARHGAP1,CDC42EP4,NF2,YKT6,PIK3R2,PRKCB,RAB9A,RHOU,EPHA2,NRP1,ATP1A1,SNX5,ARHGAP21,DEPDC1B,DNAJC5,GORASP2,RAB2A,TNFAIP3,SH3BP4,SMURF1,FERMT2,SLC25A4,RHOJ,YES1,CSNK2B,CCNF,CCSER2,VAMP3,GAB1,CTNNA1,NECTIN2 |
| 3.108e-02 | -3.47 | Basal transcription factors | KEGG pathways | ko03022 | 45 | 22 | 7161 | 2463 |
GTF2E1,MNAT1,TAF2,GTF2I,TAF10,TAF9,GTF2H4,GTF2A1,GTF2E2,GTF2H5,CCNH,GTF2A2,ERCC3,TAF11,TAF5L,CDK7,TAF7,GTF2IRD1,GTF2H2,GTF2B,GTF2F2,GTF2F1 |
| 3.108e-02 | -3.47 | Basal transcription factors | KEGG pathways | hsa03022 | 45 | 22 | 7161 | 2463 |
TAF10,GTF2I,TAF2,GTF2E1,MNAT1,GTF2E2,GTF2A1,TAF9,GTF2H4,TAF11,ERCC3,GTF2A2,CCNH,GTF2H5,GTF2B,GTF2F1,GTF2F2,GTF2IRD1,GTF2H2,TAF5L,TAF7,CDK7 |
| 3.110e-02 | -3.47 | PPP6R3 (protein phosphatase 6 regulatory subunit 3) | protein interactions | 55291 | 237 | 80 | 19454 | 5460 |
VTA1,AHCYL1,UTP25,PSMA1,RBBP7,THRAP3,GNL1,RUVBL1,ETFA,TOLLIP,GPHA2,RUVBL2,MAP1B,PPP1R12A,MTA2,TUBB4B,DNAJC2,DISC1,HDAC11,ERLIN2,TULP3,TNPO2,CSNK1E,EGLN3,CDC5L,MXI1,CEP19,HSP90AB1,FZR1,TES,SIN3A,RCHY1,PHB1,USP15,XPO1,YWHAG,DDRGK1,NT5C2,TPM3,MBD3,HSPA5,KDM1A,UFL1,SMC4,HSPA8,SQSTM1,HADHA,WNT2,SIRT7,HSP90B1,SNAI2,MRPL12,CFTR,PGRMC1,TNPO3,DUSP10,VIRMA,RPL10,ADRM1,GSK3A,MACROH2A1,WNT10B,LMBR1L,CCNF,EIF4A3,TUBA1B,ZBTB38,SP1,HSP90AA1,AP2A1,MCAT,UBE2H,DNAJB6,TXNIP,BRCA1,PSMD1,MLF1,TNFAIP3,HNRNPC,CUL3 |
| 3.110e-02 | -3.47 | CAMK2A (calcium/calmodulin dependent protein kinase II alpha) | protein interactions | 815 | 237 | 80 | 19454 | 5460 |
CHMP5,TAB1,YES1,STAT1,SENP5,GNAO1,TRIM27,PSMC5,MTG1,CAMK2N1,GRIA1,CREB1,RRP7A,SMAD2,PTTG1,HSP90AA1,DTL,MLF2,ATF1,RPL39,NTAQ1,KANSL3,PKP4,AKT1,G3BP2,ARHGEF39,GPM6A,SQSTM1,HSPA8,HDAC5,CLK1,SNRK,FAM168B,BAP1,RBMS2,RALYL,ELP3,KRTAP8-1,PIP5K1A,SSBP2,RBFOX2,NUP62,HSP90AB1,CAMK2N2,PRNP,INA,TSR2,RCHY1,SPMIP9,ARMC1,METAP1,HSPB1,YWHAB,HAX1,SMCHD1,RPL6,HMGA1,FKBP8,H2AC6,DMPK,SECISBP2L,TRIM63,HNRNPK,CAMK2G,H3C1,LASP1,SLC6A3,BAG2,IGF1R,FAM168A,KCNC1,DLG1,H2AC25,TAB2,CDK5R1,H1-3,ACTN4,DLG3,MRPL11,LYPLA1 |
| 3.113e-02 | -3.47 | cell adhesion molecule binding | molecular function | GO:0050839 | 560 | 188 | 18094 | 5411 |
AGER,CDK5R1,CDH7,CLSTN3,RARS1,VWF,RPL6,PPIA,CD81,NIBAN2,ESAM,HSPA8,BAG3,PKP4,ADD1,ICAM3,JUP,PROM1,NECTIN2,IGF1,BMPR2,SPTBN1,HSPA5,TRIM29,SNX2,RAB11B,CXCL12,CDH8,RPL15,LAMB2,RANBP1,RTN4,CD46,LYPLA2,MADCAM1,NLGN2,KLC2,CX3CL1,CNTN2,SEPTIN7,ITGAV,AHSA1,NF2,PICALM,ITGA6,CD9,EFHD2,ICAM1,TMPO,S100A11,CD200,EMP2,EHD4,RPL23A,PSEN1,THY1,TMOD3,CD40LG,CTNNB1,SEMA7A,PRDX6,CCN3,BZW2,STK38,CRKL,HMGB1,IDH1,ARGLU1,HSP90AB1,COL3A1,LASP1,SPP1,EHD1,MSN,PPFIBP1,CD226,CALR,NINJ1,EPCAM,EEF1G,H3C1,CAPG,ARHGAP1,PAK2,ZC3H15,MYO1B,LDHA,UBFD1,CNTN1,OLA1,HNRNPK,CIB2,YWHAB,UNC45A,RPL7A,EMILIN1,SNX5,CTNND1,SH3GLB2,H1-10,LCP1,DLG1,CNN3,SLC6A4,NCK1,EPHA2,ACTN4,CTNNA1,PRKCA,IZUMO1,CAPZA1,PRDX1,LGALS8,PTPN1,EIF4H,YKT6,NEO1,SWAP70,SYK,SRC,YWHAZ,ENO1,CD2AP,TES,NLGN1,ITGB8,ITGA2,EIF3E,IL1B,STAT1,CHMP5,STXBP6,RAB1A,TMIGD1,RPL29,CD151,CTNNA2,MAPRE1,GPNMB,ACVR1,PSMB6,CDH11,TAGLN2,TENM3,CHMP2B,CPE,SPTAN1,CCT8,ICAM2,ITGB5,MB21D2,CCS,EEF2,RPL24,NPTN,PAK6,CDH13,ANXA7,RPSA,FBLN5,ISG15,RPS26,SNX1,VAPB,STX5,PTPN11,FGF1,CTTN,RUVBL1,CD47,STK24,SH3GLB1,CBL,PPME1,USP8,RAN,EXOC3,SDCBP,JAML,GLOD4,RPS2,F11R,PTPRZ1,FERMT2,CD1D,PTN,SFN,MMP14 |
| 3.114e-02 | -3.47 | positive regulation of receptor internalization | biological process | GO:0002092 | 27 | 13 | 18204 | 5365 |
ATAD1,SYK,ANGPT1,TBC1D5,CD63,APLN,PCSK9,VEGFA,PICK1,GH1,GREM1,AP2M1,SFRP4 |
| 3.114e-02 | -3.47 | programmed necrotic cell death | biological process | GO:0097300 | 27 | 13 | 18204 | 5365 |
TNF,NLRP6,FAS,TLR3,TP53,BAX,SPATA2,IRF3,TRAF2,PPIF,BIRC2,ATG9A,FASLG |
| 3.114e-02 | -3.47 | cytokine production | biological process | GO:0001816 | 27 | 13 | 18204 | 5365 |
ADGRG1,CMA1,IL6,CD226,SLAMF9,ITGAV,CD2AP,TNF,COL3A1,TLR3,FOXP3,FURIN,IL1B |
| 3.114e-02 | -3.47 | positive regulation of interleukin-17 production | biological process | GO:0032740 | 27 | 13 | 18204 | 5365 |
MYD88,PRKCQ,OSM,CCL1,IL12B,IL15,IL18,JAK2,PHB1,IL23A,IL2,IL21,IL6 |
| 3.114e-02 | -3.47 | positive regulation of ubiquitin-protein transferase activity | biological process | GO:0051443 | 27 | 13 | 18204 | 5365 |
FBXW7,TOPORS,UBE2L3,ARRDC3,SKP1,FZR1,CDC20,UBE2S,RPS2,MAGEC2,PTEN,CDKN1B,RBCK1 |
| 3.114e-02 | -3.47 | mitophagy | biological process | GO:0000423 | 27 | 13 | 18204 | 5365 |
TP53,MAP1LC3B,ATG7,ATG4A,ATG4C,SQSTM1,FUNDC1,TAFAZZIN,RETREG1,CTSK,RIMOC1,BECN1,PHB2 |
| 3.122e-02 | -3.47 | ENOX2 (ecto-NOX disulfide-thiol exchanger 2) | protein interactions | 10495 | 31 | 14 | 19454 | 5460 |
RPP25L,SRPK2,VIRMA,CIB3,SRSF4,SNRPA,TUBB4B,STAMBPL1,TFIP11,POP5,GORASP2,SOX2,NTAQ1,MLLT6 |
| 3.122e-02 | -3.47 | ARL14EP (ADP ribosylation factor like GTPase 14 effector protein) | protein interactions | 120534 | 31 | 14 | 19454 | 5460 |
IFT172,ARPC2,ZMYM2,RPS27A,PLEKHF2,YWHAH,FAF2,YWHAG,XPO1,CUL3,SNAP29,YWHAB,ACTR2,YWHAZ |
| 3.122e-02 | -3.47 | SGCZ (sarcoglycan zeta) | protein interactions | 137868 | 31 | 14 | 19454 | 5460 |
ATP5IF1,RTN4,ATP5F1B,CERS2,GNPTG,RANGRF,ATP5F1D,ATP5PD,KDSR,ATP5PB,CNNM4,FAM241A,FAM241B,ACACA |
| 3.122e-02 | -3.47 | HECTD4 (HECT domain E3 ubiquitin protein ligase 4) | protein interactions | 283450 | 31 | 14 | 19454 | 5460 |
HNRNPL,VIRMA,ESR2,BTG3,UBE2L3,TOP3B,MYC,AR,YWHAH,YWHAG,MAGEA4,YWHAZ,SMAD4,YWHAB |
| 3.122e-02 | -3.47 | ZNF202 (zinc finger protein 202) | protein interactions | 7753 | 31 | 14 | 19454 | 5460 |
ZMYM2,SCNM1,NAA11,SEPHS1,SNX2,LMO4,ZMYM3,PCBD1,CEP70,ZNF250,SSX2IP,SCAND1,ZNF473,MAD2L1BP |
| 3.122e-02 | -3.47 | CYTH3 (cytohesin 3) | protein interactions | 9265 | 31 | 14 | 19454 | 5460 |
CYTH1,APEX1,ESR2,VIRMA,OIP5,IPCEF1,CSK,TOP3B,WDR83,IFI35,GNAQ,FOSL2,PIK3CA,SCHIP1 |
| 3.122e-02 | -3.47 | SLC7A8 (solute carrier family 7 member 8) | protein interactions | 23428 | 31 | 14 | 19454 | 5460 |
FITM2,TMEM14B,SMPD2,SYNJ2BP,SIGLEC5,TMEM208,SLC25A46,PXMP2,TMEM60,MFSD3,REEP4,GPR89A,DERL1,COMT |
| 3.122e-02 | -3.47 | IQCE (IQ motif containing E) | protein interactions | 23288 | 31 | 14 | 19454 | 5460 |
GPSM3,PSMA3,TRIM27,ARL10,RIGI,HNRNPF,MGAT5B,CEP70,TTC23,SOX2,MYL12B,TOP3B,TRIM23,PSMD14 |
| 3.122e-02 | -3.47 | ADPRS (ADP-ribosylserine hydrolase) | protein interactions | 54936 | 31 | 14 | 19454 | 5460 |
GLOD4,HSPB1,ACO2,IFI35,FEN1,MYC,FRA10AC1,NDUFAB1,FCGR2A,PGM1,PRNP,NCBP2,SOD1,TNKS |
| 3.122e-02 | -3.47 | IL32 (interleukin 32) | protein interactions | 9235 | 31 | 14 | 19454 | 5460 |
BCL6,STX12,STX6,RPL4,PRKCE,SNRNP70,NDFIP1,FGFR1,NDN,ZBTB16,STX10,HSPA8,VAMP3,BMPR1A |
| 3.127e-02 | -3.47 | EFNA3 (ephrin A3) | protein interactions | 1944 | 106 | 39 | 19454 | 5460 |
TUBA1A,EEF1A1,TPRA1,JCHAIN,PRSS23,TRMT112,ACACA,TUBB4B,RPA2,HSP90B1,EWSR1,LCN1,WNT7A,PABPC1,CCT8,RPS13,HSPA5,EPHA4,ATP5F1A,GAPDH,PDIA3,CALR,LYZ,EPHA2,PRSS1,RPL23,DNAJC10,PABPC1L,PRMT5,ALB,EFNA3,RPS3,RPL12,TUBA1B,CYP27A1,ACTB,TUBB,TCP1,RPL7 |
| 3.127e-02 | -3.47 | KRT13 (keratin 13) | protein interactions | 3860 | 106 | 39 | 19454 | 5460 |
COPS5,CUL2,CUL3,ATG9A,PSMB2,ZNF688,DNAJB6,UBE2H,CCHCR1,SHC1,RC3H2,PSMB1,KRT8,ALB,TSG101,TMSB4X,EIF4E2,RNF208,CEP57L1,DES,PPP1R18,CAND1,SPG21,CFTR,SOX2,MYH1,HGS,KRT7,HEXIM1,GRAP2,LSM2,NEFL,ATP5PO,HSPA8,FANCG,MEPCE,PSMA1,SGF29,NEDD8 |
| 3.127e-02 | -3.47 | H3-3B (H3.3 histone B) | protein interactions | 3021 | 106 | 39 | 19454 | 5460 |
HIRA,RNF113A,ASF1A,H1-6,RBBP7,SS18,RIGI,SSRP1,MCM6,TOMM20,GINS3,UBR7,H2AX,PDHA1,GINS4,CBX3,EZH2,RNF8,MACROH2A2,CCR1,LACC1,PARP2,UBN1,MACROH2A1,RBBP4,CBX5,RAB39B,WWP2,CREBBP,SMARCA5,MCM4,PRKACB,CD81,FBXO7,H2AC4,TIAM1,PPTC7,BRD3,ICAM1 |
| 3.154e-02 | -3.46 | FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) | protein interactions | 10160 | 128 | 46 | 19454 | 5460 |
RAF1,VPS33A,CAPZA2,RND3,GEMIN7,MOB3C,NUPR1,KRAS,LSM4,CAMKV,FLOT1,MRPS35,FGF1,RHOG,LSM3,WDR6,RAB35,GJA1,RAC2,ARF6,HNRNPL,RHOH,PSD2,SNRPD3,DIRAS3,SNRPN,CDC42,RND2,SDC2,RPA2,FGFR1,PIH1D1,RHOU,RPA3,HADHA,SQSTM1,AKAP1,STAU1,STX7,BTF3,SNRPB,DNAJC5,LAMTOR1,RHOB,TAB1,RHOJ |
| 3.157e-02 | -3.46 | vascular process in circulatory system | biological process | GO:0003018 | 273 | 95 | 18204 | 5365 |
SLCO3A1,ADRB2,MIR23A,AGER,DDAH1,SLC6A1,SLC7A8,SLC5A6,GCLC,RGS2,KCNMA1,SLC1A2,DBH,SLC1A1,AVPR1B,SLC2A3,GPX1,YES1,TFRC,OXTR,KCNMB1,SLC2A1,TNF,ACTA2,HRH2,LRP3,ROCK2,ABCB1,FOXC2,HBB,SLC29A1,SLC8A1,SOD1,ATP1A2,SLC22A8,UTS2,ADRB3,CD38,SLC12A2,SLCO2B1,KCNJ8,SCPEP1,DRD1,ASIC2,SLC4A8,ATP8A1,NHERF1,NPPC,ATP2B4,PDE2A,ADRB1,ABCG2,SNTA1,SLC1A3,LEP,EXT1,P2RY1,ANGPT1,SOD3,SRC,ADRA1A,ADORA1,HTR2A,FERMT2,ROCK1,PTP4A3,LEPR,SOD2,ABCC5,SLC7A1,AKAP12,SLC15A2,SLC16A1,MIR153-1,CTNNBIP1,MIR21,SLC6A6,ABCC2,SLC38A3,TACR1,KCNMB2,VEGFA,CD36,SLC38A2,SLC38A1,UCN,BMPR2,UTS2R,CAV1,SLC6A4,EDNRA,FABP5,VSTM4,MKKS,HTR1A |
| 3.158e-02 | -3.46 | CEP290 (centrosomal protein 290) | protein interactions | 80184 | 147 | 52 | 19454 | 5460 |
FKBP4,AK2,CAMSAP2,MED4,SSX2IP,NDC80,H2AC14,YWHAH,HYPK,PRNP,MIF,CAND1,PEG10,GYS1,SSBP1,ARPC3,DISC1,PNMA2,EZH2,CSTPP1,SUPT5H,CSNK1E,ANP32A,MAPK10,AKAP12,PTGES3,PICK1,CHTOP,MAPRE1,CREBBP,CSK,RAB2A,MTPN,H2BC9,LDHA,CEP97,APEX1,CYB5R3,POLR3H,ISOC1,TRIM36,WDR83,KLHL3,CDKN1A,PLP2,KDELR2,FAXC,FTL,HSPA5,TRIM52,SQSTM1,EMG1 |
| 3.158e-02 | -3.46 | EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase) | protein interactions | 1962 | 147 | 52 | 19454 | 5460 |
ACTB,KCTD9,TRIM54,DES,PRRC2A,TRAF1,PNMA1,PRKRA,TRIM27,CYB561,TRIM23,OPRM1,RIOK2,LZTFL1,CMTM6,ORMDL1,DVL2,JAGN1,NCDN,TRIM5,ARMCX3,ZCCHC17,EHHADH,DHRS4,FUNDC1,SNRNP27,CDR2L,BOLL,RPRM,HSD17B11,SSX2IP,GAS8,TRIM63,SSNA1,SMN1,LEPROTL1,BHLHE40,RUSF1,PTGES,PICK1,TRIM21,RP9,TMEM31,SYNGR3,SDR16C5,ZBTB26,VAC14,PNMA5,PAQR8,RAF1,ACTR1A,WBP11 |
| 3.158e-02 | -3.46 | RNA polymerase II preinitiation complex assembly | biological process | GO:0051123 | 49 | 21 | 18204 | 5365 |
MED29,TAF11,MED4,TAF10,TAF7,DR1,MED31,MED30,MED17,MED10,TAF2,GTF2B,MED9,MED21,MED11,TAF9,GTF2A2,MED22,GTF2A1,MED23,MED27 |
| 3.162e-02 | -3.45 | Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | REACTOME pathways | R-HSA-159763 | 9 | 6 | 10285 | 3229 |
F10,PROS1,F7,F2,BGLAP,F9 |
| 3.163e-02 | -3.45 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | REACTOME pathways | R-HSA-110313 | 41 | 19 | 10285 | 3229 |
POLE3,PCNA,RFC4,RPA2,UBB,RPS27A,POLD2,UBA52,POLD4,RFC5,RCHY1,RPA3,RFC2,PCLAF,UFD1,RFC3,ISG15,MAD2L2,POLE4 |
| 3.163e-02 | -3.45 | Signaling by FGFR4 | REACTOME pathways | R-HSA-5654743 | 41 | 19 | 10285 | 3229 |
UBA52,RPS27A,UBB,PPP2R1A,PIK3CA,CBL,GAB1,HRAS,PPP2CB,FGF23,PTPN11,KRAS,FGF1,FGF17,SHC1,FGF16,FRS3,SRC,PIK3R1 |
| 3.163e-02 | -3.45 | Dual Incision in GG-NER | REACTOME pathways | R-HSA-5696400 | 41 | 19 | 10285 | 3229 |
GTF2H4,POLE3,PCNA,RFC4,PARP2,UBB,RPA2,POLD2,RPS27A,GTF2H2,UBA52,GTF2H5,POLD4,RFC5,RPA3,RFC2,ERCC3,RFC3,POLE4 |
| 3.171e-02 | -3.45 | snoRNA binding | molecular function | GO:0030515 | 32 | 15 | 18094 | 5411 |
NUDT4,NUDT16,WDR3,DKC1,NUDT7,NUDT1,IMP4,UTP25,NOP58,NHP2,NUDT5,IMP3,ISG20,XRCC5,UTP6 |
| 3.179e-02 | -3.45 | translation elongation factor activity | molecular function | GO:0003746 | 19 | 10 | 18094 | 5411 |
GTPBP2,GFM2,EEF1G,EEF1B2,EIF5A2,GTPBP1,GFM1,EEF1A1,TUFM,EEF2 |
| 3.180e-02 | -3.45 | RNF38 (ring finger protein 38) | protein interactions | 152006 | 103 | 38 | 19454 | 5460 |
CTSD,RUNX1,LDB1,UBE2D1,H2AZ2,MYO6,UBE2H,MAP4,GNG12,RNF208,UBE2N,ENO1,EFHD2,RAN,CORO1C,KRT8,RPL7,SPTAN1,LYAR,TP53,KRTAP8-1,ACTN4,CD59,GGCT,H2BC11,ATP5PO,CAPZA2,KRT7,MYL6,RPL31,PPP1R12A,SPECC1L,MYO1B,TRIM21,LASP1,UBE2D3,ZDHHC17,HSPA5 |
| 3.180e-02 | -3.45 | SRBD1 (S1 RNA binding domain 1) | protein interactions | 55133 | 103 | 38 | 19454 | 5460 |
SNRNP40,RPS16,ZNF330,H2AZ1,RPS3,TRIM44,GSK3A,PRR3,RC3H2,SNRNP70,MECP2,KPNA1,WWP2,MRPS35,IFI16,MYC,DDRGK1,CSNK2A1,CBX7,FBXW7,RPL4,UFL1,H3C1,KRAS,COIL,RPS13,RPL28,RPA3,PRKCB,HSP90B1,GRM2,APOBEC3C,RPA2,RPN1,MYL6,SART3,RPL26L1,RPL27A |
| 3.184e-02 | -3.45 | MTNR1A (melatonin receptor 1A) | protein interactions | 4543 | 163 | 57 | 19454 | 5460 |
COG1,CAND1,PRELID1,COMT,TMEM14A,NAP1L5,LAPTM4A,FAM241B,YWHAB,CALR,BAZ1B,GAPDH,EXOC1,LRP3,TMEM33,KRAS,H2AC6,FSTL1,GNA11,PDIA6,SLC6A3,ZC3H11A,RPL3,SURF4,GNAI3,KLHL12,RAP1A,SNAPIN,ACTB,TVP23B,TUBB,GNB1,GNAI2,ENO2,CTNNA1,ABHD14B,RTRAF,YWHAZ,ATP5MC3,CUL3,HMOX2,COX11,SRI,EEF1G,HNRNPA0,HSPA5,RNF41,GNB4,SLC2A3,TMX2,VAPB,TM9SF1,PGRMC1,CNP,ZDHHC16,STXBP1,CCDC167 |
| 3.184e-02 | -3.45 | MYO5C (myosin VC) | protein interactions | 55930 | 163 | 57 | 19454 | 5460 |
EIF2B5,SPTAN1,PTP4A3,NDC80,TPM3,PALM2AKAP2,PPP1R12A,MYO1B,RAB3B,TRIM37,ERLEC1,DPM2,RIGI,CAPZA1,TP53,ACTN4,ISG15,ACTR2,PNMA2,CAPZA2,ARPC3,CTTN,LURAP1,CCNF,ANAPC2,DKK3,TMOD3,DAPK3,CHCHD3,SH3BGRL,RAB11A,CREB3,CDC16,MYC,GMNN,TUFM,PPP1CC,NONO,AR,ARHGAP21,MYO6,AP2A1,ABCG2,FOS,SPECC1L,ARPC2,HSPA8,PGK1,P4HA2,CRYL1,FTL,TRIM52,SPTBN1,GABRA1,PPP1CB,HECTD1,TMOD1 |
| 3.184e-02 | -3.45 | SAP30 (Sin3A associated protein 30) | protein interactions | 8819 | 163 | 57 | 19454 | 5460 |
EZH2,SAP30L,SMARCB1,MTA2,HBP1,PHF23,ZNF704,MAX,MTA3,TOP3B,RPL15,ING1,RBBP7,MRPL22,PHF1,BCL7B,TGIF2,CLIC2,DPY30,CSNK2A1,DNTTIP1,HDAC6,SHPRH,BRMS1L,MDM2,H2AZ1,SIN3A,LDLR,GATAD1,EED,MYBL2,ZCCHC17,CTBP1,MXD1,SAP30BP,ACTL6A,TGIF2LX,KDM1A,HDAC3,HSPA5,MBD3,SAP18,HSPA8,SP1,HSP90AA1,SMARCA5,RPF2,BRMS1,PCBD1,CPSF2,RBBP4,RAN,EZH1,PHF12,UBASH3B,CMBL,ING2 |
| 3.186e-02 | -3.45 | S (spike glycoprotein) | protein interactions | 1489668 | 221 | 75 | 19454 | 5460 |
ITGA6,PTK7,KRT8,NELL2,SLC39A10,RAP1B,RPS27L,KCTD3,ALCAM,CDK17,GAPDH,NT5C2,MPG,LANCL2,SFTPD,SLC2A1,RHOG,RPL23,CBL,C1GALT1C1,DENND6B,LSM14A,FAM168A,RAB13,SLC16A1,EFNB1,S100A10,THRAP3,ENKD1,MEPCE,SLC6A8,TNRC6C,RAP1A,MARCKSL1,TPBG,TULP3,HINT3,SMNDC1,MOXD1,CD209,DDX42,PAFAH1B3,ZNHIT6,NECTIN2,CCSER2,CD47,LGALS3,ACTB,STARD7,F11R,MGST3,DAPK3,RPL19,DYRK1A,SEC13,RHOB,LGALS8,EIF3G,ALKBH5,EPHA2,EXOSC1,NRP1,FAM222B,RTKN,RAMAC,SLC31A1,CNTN1,NOTCH2,LDAH,YIPF5,CDC42,PCLAF,UBAC2,CD46,NUFIP2 |
| 3.189e-02 | -3.45 | human chr6q22.31 | chromosome location | human chr6q22.31 | 28 | 11 | 26134 | 5823 |
CLVS2,MIR548B,PLN,TPD52L1,FABP7,GJA1,HDDC2,SERINC1,ASF1A,HEY2,PKIB |
| 3.205e-02 | -3.44 | adnexal_tumour | COSMIC cancer mutations | adnexal_tumour | 25 | 12 | 16828 | 4835 |
HRAS,KRAS,IDH1,EWSR1,SF3B1,TP53,KIT,CTNNB1,JAK2,AKT1,PIK3CA,PTEN |
| 3.205e-02 | -3.44 | Spitz | COSMIC cancer mutations | Spitz | 25 | 12 | 16828 | 4835 |
HRAS,KRAS,LSM14A,BAP1,GNAQ,GOLGA5,TP53,GNA11,KIT,PPFIBP1,LMNA,TPM3 |
| 3.215e-02 | -3.44 | TP53 Regulates Transcription of Cell Cycle Genes | REACTOME pathways | R-HSA-6791312 | 49 | 22 | 10285 | 3229 |
GADD45A,CCNB1,EP300,PLAGL1,CDKN1B,RGCC,CNOT8,CNOT2,CDK1,CDKN1A,E2F4,BTG2,CCNA2,PCBP4,TFDP2,CNOT6L,CNOT7,BAX,SFN,PCNA,TP53,CNOT6 |
| 3.216e-02 | -3.44 | Claudin_CS | interpro domains | IPR017974 | 22 | 11 | 18521 | 5414 |
CLDN11,CLDN6,CLDN1,CLDN4,CLDN14,CLDN8,CLDN22,CLDN3,CLDN9,CLDN12,CLDN24 |
| 3.219e-02 | -3.44 | RBM5 (RNA binding motif protein 5) | protein interactions | 10181 | 125 | 45 | 19454 | 5460 |
SNRPE,CASK,RPL15,SOX2,WBP11,RAF1,CCAR1,SRSF4,LSM4,EMC2,RPL3,HSPD1,BCL2L1,DDX23,GAPDH,DDRGK1,HNRNPA1,COPS5,RBM17,MOV10,PRPF19,DHX15,CDC5L,DBT,MIRLET7G,CCAR2,SNRPA1,HNRNPL,LSM2,H1-5,WDR77,LSM8,ZDHHC17,MIRLET7I,FBXW11,POMP,H2BC9,MYC,CREBBP,RPL19,ESR2,LRIF1,MIRLET7D,SNRNP40,RPS3 |
| 3.219e-02 | -3.44 | SOCS6 (suppressor of cytokine signaling 6) | protein interactions | 9306 | 125 | 45 | 19454 | 5460 |
UBE2I,CDC7,AP2M1,GAB1,PFDN4,SP1,EPHA2,HSP90AA1,WDR20,AR,PIK3R3,PIK3R2,KDM1A,PDHB,MAIP1,ACACA,MET,RNF7,FRS3,TIMM13,KIAA0232,ATXN10,DCUN1D1,TES,CDC23,HAX1,ELOC,API5,YWHAG,YWHAH,SAV1,PIK3R1,BMPR1B,RBCK1,KIT,FBXO11,SLC25A11,NDUFA4,RAB1A,SLC25A10,DCUN1D5,ACVR1,TUBB4B,GFPT1,TUBA1A |
| 3.223e-02 | -3.43 | KDF1 (keratinocyte differentiation factor 1) | protein interactions | 126695 | 192 | 66 | 19454 | 5460 |
SMARCA5,TUFM,RBM27,DNAJC10,SERPINH1,RAN,STUB1,PSPC1,UQCRC2,ODR4,RTRAF,MATR3,UBB,ZNF326,MED23,CTBP1,SLC25A3,ACACA,NUFIP2,GPHN,RPL4,SMC4,NDUFS2,RANBP10,ZNF24,DDX50,IQSEC1,TRA2A,PPIL4,CSNK2A1,PPM1B,SMAD4,IKBKB,DDX1,ZNF664,RPL8,THOC2,SIN3A,WDR6,HRAS,RPL7,TCP1,MAPRE2,HNRNPL,DHX15,AKAP17A,TRMT1L,RPL15,GFPT1,NDUFS3,RPN1,RPL18,SLC25A11,NKRF,SLC25A5,DHX9,PC,SLC16A1,RPL3,HNRNPF,KRAS,PRDX4,PRPS1,MEPCE,RNF20,MCM6 |
| 3.229e-02 | -3.43 | HIP1R (huntingtin interacting protein 1 related) | protein interactions | 9026 | 144 | 51 | 19454 | 5460 |
CAPZA2,AQP3,CCR1,CYB5B,CRKL,COMTD1,TOP3B,MAP2K3,MGARP,SOX2,EWSR1,SMAD4,PPM1B,STAMBPL1,UPK1A,NDC80,DIRAS3,CDC5L,CD274,TSG101,SDC2,RPA2,STX17,PICALM,TFIP11,MTMR6,SLC15A1,STX7,VPS28,SLC39A9,CD40,RPA3,LAMTOR1,SYP,RHOB,TYROBP,MYC,TUFM,IRF2BP1,CEP41,ACTB,DYNLL1,APLNR,ESR2,PSPC1,SCN2B,CCNF,CTTN,TRIM27,RTRAF,SLC1A1 |
| 3.229e-02 | -3.43 | RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 23168 | 144 | 51 | 19454 | 5460 |
MYC,PTPN11,RIOK2,PSMD1,PIP4K2C,PLEKHJ1,PTTG1,CDC73,UBE2H,PELO,ZNF330,SYT2,PSMD4,STAT1,FBXO22,SRPK2,APEX1,SEC22B,DENND2D,ETF1,ELP3,CDK1,LMNA,USE1,RPA3,EP300,HADHA,TCEA1,COIL,CD81,CSNK2A1,SKIC8,DDX23,VPS4A,RPL35A,THOC1,H2AJ,CENPM,SUPT5H,PPP2R1A,CBX3,ZRANB2,RBPJ,SNIP1,RPL31,BAG2,KRAS,RUVBL1,FGF12,SSRP1,RIGI |
| 3.229e-02 | -3.43 | USP8 (ubiquitin specific peptidase 8) | protein interactions | 9101 | 144 | 51 | 19454 | 5460 |
RPA2,VPS4B,CHMP1A,FGFR1,ACAA2,LEPR,STAT6,PTAR1,BET1,USP8,CHMP2B,RNF41,RPA3,SQSTM1,COMMD2,YWHAZ,RIT1,DNAJB6,AKT1,SFN,TRIM54,BTG3,SRC,VIRMA,CCNF,PTEN,MCPH1,UBE2I,IQCF5,CHMP4C,GRAP2,KRAS,CHMP1B,TRIM63,TGFBR2,VAMP8,BACE1,CD83,NTRK2,SPP1,ID1,YWHAB,USP15,YWHAG,YWHAH,SPPL3,STX6,CHMP2A,CD274,RNF128,GJA1 |
| 3.233e-02 | -3.43 | TMEM184A (transmembrane protein 184A) | protein interactions | 202915 | 100 | 37 | 19454 | 5460 |
EMC2,TMEM87A,TMEM209,HS2ST1,RER1,MCMBP,SLC7A1,AGPAT5,ISCU,RBM38,MTX2,RABL3,RRM1,TOMM22,DHRS7B,CAV2,RTF2,PDP2,SIGMAR1,SURF4,GTF2F2,MPDU1,RCHY1,APEX1,CAV1,UQCRQ,VKORC1L1,AASDHPPT,DERL2,REEP4,HNRNPL,KCTD15,MGST3,MMUT,SYNJ2BP,MOV10,ENDOD1 |
| 3.233e-02 | -3.43 | MAP1S (microtubule associated protein 1S) | protein interactions | 55201 | 100 | 37 | 19454 | 5460 |
STK4,ATG7,EDEM1,FAM174A,UBXN6,UBE2H,CAMSAP2,MAPRE1,FBXW11,ATG3,SMAD4,FAS,MAP1LC3A,CCNF,SYNCRIP,STK3,SRPK2,WIF1,FBXO22,KIF2A,SOCS3,MAP1LC3B,MND1,TOP3B,H2BW1,TRIM36,VAPB,RPA2,PML,HNRNPA2B1,PPM1G,RPA3,TRAPPC1,MAP1B,PTGES3,TOLLIP,B2M |
| 3.239e-02 | -3.43 | FKBP_PPIASE | prosite domains | PS50059 | 15 | 8 | 12186 | 3388 |
FKBP4,FKBP8,FKBP2,FKBP10,AIP,FKBP14,FKBP1B,FKBP1A |
| 3.239e-02 | -3.43 | CRYSTALLIN_BETA_GAMMA | prosite domains | PS50915 | 15 | 8 | 12186 | 3388 |
CRYBA1,CRYBA2,CRYBA4,CRYBB3,CRYBB2,CRYGA,CRYGD,CRYGB |
| 3.243e-02 | -3.43 | Colorectal cancer | KEGG pathways | hsa05210 | 60 | 28 | 7161 | 2463 |
RAC2,PIK3R3,BAX,SMAD2,PIK3CA,BAD,AKT2,JUN,CTNNB1,MAP2K1,AKT3,MYC,TGFBR2,MSH6,SMAD4,MAPK10,CCND1,RAF1,BIRC5,FOS,TGFB3,TGFB2,PIK3R1,KRAS,TP53,PIK3R2,SMAD3,AKT1 |
| 3.243e-02 | -3.43 | Colorectal cancer | KEGG pathways | ko05210 | 60 | 28 | 7161 | 2463 |
TGFBR2,MYC,AKT3,CTNNB1,MAP2K1,AKT2,JUN,BAD,SMAD2,PIK3CA,BAX,PIK3R3,RAC2,AKT1,SMAD3,PIK3R2,TP53,KRAS,PIK3R1,TGFB3,TGFB2,FOS,RAF1,BIRC5,CCND1,MAPK10,SMAD4,MSH6 |
| 3.256e-02 | -3.42 | transcription factor TFIIH core complex | cellular component | GO:0000439 | 12 | 7 | 19108 | 5553 |
CDK7,MNAT1,GTF2H4,CCNH,GTF2H5,ERCC3,GTF2H2 |
| 3.256e-02 | -3.42 | proteasome regulatory particle, base subcomplex | cellular component | GO:0008540 | 12 | 7 | 19108 | 5553 |
PSMC1,PSMD10,PSMC4,PSMC3,PSMC5,PSMD1,PSMD4 |
| 3.256e-02 | -3.42 | proton-transporting ATP synthase complex, coupling factor F(o) | cellular component | GO:0045263 | 12 | 7 | 19108 | 5553 |
ATP5MC1,ATP5MG,ATP5PO,ATP5MC3,ATP5PF,ATP5PD,ATP5PB |
| 3.256e-02 | -3.42 | iron-sulfur cluster assembly complex | cellular component | GO:1990229 | 12 | 7 | 19108 | 5553 |
NDUFAB1,BOLA1,BOLA2B,BOLA3,ISCU,GLRX5,FXN |
| 3.257e-02 | -3.42 | positive regulation of secretion by cell | biological process | GO:1903532 | 289 | 100 | 18204 | 5365 |
INHA,PPARG,SYT4,OPRK1,RGCC,TACR1,ILDR1,PLCB1,PCK2,CHRNB2,UCN,SLC6A4,C1QTNF1,ACHE,CHMP2A,SNAP25,PARD6A,VEGFC,TLR4,LEP,LRRC8A,PTPN11,PPID,SCAMP5,MIF,FGFR1,P2RY1,GABBR1,RASL10B,RAB9A,PTGES,IL13,VPS4A,BGLAP,PPIA,CREB1,RAB8B,NLGN1,IFNG,FGR,KCNB1,SDC4,ACSL4,DYNLL1,SDCBP,RAB3A,CARTPT,F2,C2CD2L,ARF6,SLC12A2,TLR2,NLGN2,RAB5A,GHRL,CD2AP,CFTR,CD38,RAB27A,GNA11,SRI,SLC4A8,BAD,PRKCB,CHRM3,PRKCE,HGS,NR1H2,SPHK2,SYBU,JAK2,STXBP1,TSG101,MAP2K6,OR51E2,PFKFB2,SMAD4,SELENOT,S100A10,NKX3-1,VPS4B,STX1A,CDK5,TGFB3,SPP1,IL1B,GOLPH3L,VAMP8,CXCL12,HFE,OXTR,RETN,VAMP7,RAB3D,KLRC2,OSBP,IL1A,TGFB2,APBB3,IGF1 |
| 3.266e-02 | -3.42 | STAG2 (STAG2 cohesin complex component) | protein interactions | 10735 | 218 | 74 | 19454 | 5460 |
PSMD1,PRPF31,SMARCA5,USP13,OPRM1,GPR17,CUL3,APEX1,ESR2,BCCIP,MAD2L2,VIRMA,COPE,MATR3,ACTB,RBBP4,CALML5,PTEN,LMBR1L,CCNF,TUBA1B,ZNF174,ZNF330,RPA2,HBB,FAM234A,H1-5,PIP5K1A,MBD3,WFDC5,COIL,FTL,NPTN,GTF2I,HAND2,STAU1,SF3B1,HSPA8,DDX5,RPA3,CD40,SIRT7,LYZ,KPNA1,OSBPL8,KDM2A,XPO1,CITED1,CDC5L,HNRNPL,SUMO2,PWP2,SSU72,DNM2,RCHY1,MTA2,SKA3,SIGLECL1,CBX3,BZW2,EEF1A1,SOX2,SPRR1B,COMTD1,GTF3C3,RAD21,RIGI,G3BP1,H3C1,RBBP7,THRAP3,SEMA4C,EFNB1,CD83 |
| 3.274e-02 | -3.42 | negative regulation of protein secretion | biological process | GO:0050709 | 75 | 30 | 18204 | 5365 |
IL12A,IL1B,DPH3,KCNJ11,PPP3CA,GNAZ,GHRL,OPRM1,CD200,ADTRP,HADH,DRD3,MIR146A,PTPN11,SYT4,NDUFAF2,IL12B,UCP2,ACVR1C,ENY2,KCNB1,GNAO1,JAGN1,FKBP1B,ERP29,CCN3,RSAD2,SFRP1,CHGA,NEO1 |
| 3.277e-02 | -3.42 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | biological process | GO:1902229 | 38 | 17 | 18204 | 5365 |
CDKN2D,TRIM32,SNAI2,TAF9,NACC2,TPT1,RPL26,ING2,RPS3,HNRNPK,CCAR2,ACKR3,BCL2L1,CLU,MIF,CXCL12,KDM1A |
| 3.277e-02 | -3.42 | positive regulation of DNA binding | biological process | GO:0043388 | 38 | 17 | 18204 | 5365 |
IFNG,CEBPG,TRAF6,GTF2B,PAX6,NME1,DDRGK1,HMGB1,IGF1,EDF1,TRIM6,RB1,HAND2,MMP9,NIBAN2,TXN,PPARG |
| 3.277e-02 | -3.42 | negative regulation of endothelial cell apoptotic process | biological process | GO:2000352 | 38 | 17 | 18204 | 5365 |
SCG2,ICAM1,IL4,NDNF,MIR30E,IL10,ANGPT1,MIR495,NFE2L2,KRIT1,MIR30B,IL13,TNFAIP3,SEMA5A,TERT,MIR126,MIR590 |
| 3.277e-02 | -3.42 | positive regulation of telomere maintenance via telomere lengthening | biological process | GO:1904358 | 38 | 17 | 18204 | 5365 |
XRCC5,CCT7,HNRNPA2B1,NEK7,CCT8,TNKS2,TCP1,CTNNB1,CCT5,TNKS,PKIB,MAPKAPK5,PRKCQ,HNRNPA1,DKC1,NEK2,CCT2 |
| 3.283e-02 | -3.42 | LIAS (lipoic acid synthetase) | protein interactions | 11019 | 34 | 15 | 19454 | 5460 |
RIT1,PTTG1,CDK12,PDHA1,MED10,CFTR,MED22,LIAS,RPL35,HSCB,KRAS,SRSF7,RPLP2,TCOF1,ALDH1A3 |
| 3.283e-02 | -3.42 | SOX13 (SRY-box transcription factor 13) | protein interactions | 9580 | 34 | 15 | 19454 | 5460 |
TRAF2,XPO1,CEP85,H1-5,HNF1B,NUP62,FOXP1,PRKAG1,MGME1,KCTD20,ESR2,FOXP4,FOXP2,ZNF7,ZBTB2 |
| 3.283e-02 | -3.42 | ZBTB8B (zinc finger and BTB domain containing 8B) | protein interactions | 728116 | 34 | 15 | 19454 | 5460 |
MATCAP1,ILF2,ZNF250,MORF4L1,NTAQ1,LMO3,CEP70,SPPL3,FXR2,AP1M1,SMURF1,DVL2,AP2M1,CDC7,SGTA |
| 3.283e-02 | -3.42 | RAB27B (RAB27B, member RAS oncogene family) | protein interactions | 5874 | 34 | 15 | 19454 | 5460 |
NUP35,DES,ESR2,CCDC186,PRNP,AKAP1,RAB27A,HRAS,CINP,CCR1,LMNA,GORASP2,OTULINL,SOX2,DHPS |
| 3.283e-02 | -3.42 | IL20RB (interleukin 20 receptor subunit beta) | protein interactions | 53833 | 34 | 15 | 19454 | 5460 |
CLU,ACVR1B,RAP1B,BSCL2,JAK1,BMPR1A,LRP10,ITM2B,TMEM30A,TMEM59L,NCR3LG1,FGFR1,TMEM59,IFNGR1,DHRS7 |
| 3.283e-02 | -3.42 | TMEM184B (transmembrane protein 184B) | protein interactions | 25829 | 34 | 15 | 19454 | 5460 |
RAB9A,RAC2,SNIP1,INPPL1,YTHDF1,CCR6,CDC42,HCST,LPAR6,ATG16L1,MICB,REN,PDCD1,TIMM23,SYP |
| 3.283e-02 | -3.42 | DELEC1 (deleted in esophageal cancer 1) | protein interactions | 50514 | 34 | 15 | 19454 | 5460 |
CSNK1E,PPP1CC,NONO,PPP1CB,CSNK2A1,PPP2R1A,EZH2,CIPC,PPP2R5E,CSNK2B,PICK1,CRY1,PRKCB,NFIL3,RORB |
| 3.283e-02 | -3.42 | WDR90 (WD repeat domain 90) | protein interactions | 197335 | 34 | 15 | 19454 | 5460 |
CCT2,MED4,MAPRE1,CSNK1E,TOP3B,CUL3,NDC80,TUBA1A,MAP1LC3B,DYNLL1,UBB,APEX1,TMEM160,THOC2,HSPA8 |
| 3.283e-02 | -3.42 | UGCG (UDP-glucose ceramide glucosyltransferase) | protein interactions | 7357 | 34 | 15 | 19454 | 5460 |
RUSF1,RHOU,CD83,PICK1,RNF133,SPPL3,CX3CL1,RHOJ,TMEM231,TMEM59,CDC42,RHOB,CTXN1,SLC20A1,TSPAN3 |
| 3.283e-02 | -3.42 | GPR89B (G protein-coupled receptor 89B) | protein interactions | 51463 | 34 | 15 | 19454 | 5460 |
B4GALT3,DNAJC1,ESR2,VIRMA,APLNR,RPA3,SERINC1,RETREG3,P2RY1,RPA2,PLD3,SLC4A8,ST3GAL1,DNAJC25,LPAR6 |
| 3.283e-02 | -3.42 | Bcas2 (BCAS2 pre-mRNA processing factor) | protein interactions | 68183 | 34 | 15 | 19454 | 5460 |
CCNQ,PRPF19,UBL5,PRKCA,WWP1,CTSA,DDX5,RPS20,HOMER3,PRCC,CDC5L,BRIX1,WDR55,PPWD1,SNRNP40 |
| 3.283e-02 | -3.42 | TINAGL1 (tubulointerstitial nephritis antigen like 1) | protein interactions | 64129 | 34 | 15 | 19454 | 5460 |
CTSK,MED31,SMAD9,CAPN1,MDFI,PI15,TOP3B,TULP3,LMO4,CD59,COPS5,CAMKV,EP300,MTDH,PRMT5 |
| 3.283e-02 | -3.42 | LGALS9C (galectin 9C) | protein interactions | 654346 | 34 | 15 | 19454 | 5460 |
SLC38A9,DAG1,ATG9A,TSPAN3,CD58,SLC12A2,PLSCR1,CD63,ATP2B4,ZDHHC17,DHX16,RRAGB,SLC7A1,CD47,LGALS3 |
| 3.283e-02 | -3.42 | HGH1 (HGH1 homolog) | protein interactions | 51236 | 34 | 15 | 19454 | 5460 |
TMEM256,EP300,TES,CCNF,MAP1B,LMBR1L,POLA2,EGLN3,HSP90AB1,IMMP2L,PTN,FBXO22,TTC4,MED31,HGS |
| 3.283e-02 | -3.42 | PRKCH (protein kinase C eta) | protein interactions | 5583 | 34 | 15 | 19454 | 5460 |
HSP90AA1,MGMT,FIS1,PRKCA,PARD6A,RHOB,MAP2K3,ST7,MTCH2,PTPN11,SRC,PRKCE,GSK3A,AKAP1,ARF1 |
| 3.283e-02 | -3.42 | CLEC12A (C-type lectin domain family 12 member A) | protein interactions | 160364 | 34 | 15 | 19454 | 5460 |
MED29,CFTR,MACO1,CLEC1A,PTPN11,GOSR2,STX6,DNAJC1,VTI1B,GOSR1,XPO5,STX18,STX10,STX5,STX8 |
| 3.283e-02 | -3.42 | DUSP15 (dual specificity phosphatase 15) | protein interactions | 128853 | 34 | 15 | 19454 | 5460 |
IGF1R,PSMC5,PTK7,SMC4,PSMD6,GTF2I,SPPL3,RPS17,PSMD1,PTPN5,PSMD3,DICER1,PSMC3,PSMD7,VAPB |
| 3.283e-02 | -3.42 | SCHIP1 (schwannomin interacting protein 1) | protein interactions | 29970 | 34 | 15 | 19454 | 5460 |
BACH1,NF2,PSMD4,PRPF18,NRBF2,TMSB4X,FOS,PSMC5,SCHIP1,EXOC3,MTMR2,RAB11A,FGF13,XPO1,EXOC5 |
| 3.285e-02 | -3.42 | ATL2 (atlastin GTPase 2) | protein interactions | 64225 | 97 | 36 | 19454 | 5460 |
YWHAB,YWHAZ,ESYT1,P2RY10,GPR17,MYC,OPRL1,VIRMA,APLNR,COPE,ARL6IP5,ADD1,HSD17B11,DPEP1,CD79B,ACACA,RPA2,HCST,RGL1,LPAR6,SNRNP27,CHRM3,SUPT5H,IL1R2,ARL6,TACR3,SLC15A1,HSCB,RTN4,DERL1,IDH1,SLC22A6,SYVN1,HSPA8,RPA3,BCL7B |
| 3.285e-02 | -3.42 | AIRE (autoimmune regulator) | protein interactions | 326 | 97 | 36 | 19454 | 5460 |
SRSF1,EIF4EBP3,TUBB,SNRPD3,HSP90AB1,UBB,POLR2B,TMPO,CREBBP,SNRPB,ATP5F1A,XPO1,LMNB1,LANCL2,H2BC17,XPOT,PABPC1,FBXO3,DDX5,HSPA8,PICK1,RUVBL2,PCNA,HNRNPF,H3C1,GDPD3,SRSF2,SSRP1,HSPA5,MSH6,RAD21,RIGI,H2AC6,MCM6,TUBB4B,HEXB |
| 3.285e-02 | -3.42 | CBLB (Cbl proto-oncogene B) | protein interactions | 868 | 97 | 36 | 19454 | 5460 |
NEDD8,KIT,PIK3R2,HNRNPK,RNF11,TICAM1,TGFB1I1,MYD88,HAPSTR1,CRY1,VAV2,GRAP2,CRKL,SPRY1,SYK,IPO8,TP53,TANK,PRMT2,TRAF2,CD2AP,STAT5A,DAPK1,YES1,VPS26C,UBE2L3,UBASH3B,SHC1,TRAF6,NCK1,CBL,NLRP3,PIK3R1,PTPN11,CD81,GORASP2 |
| 3.288e-02 | -3.41 | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 62 | 25 | 16828 | 4835 |
RAB33A,B2M,STAT6,HRAS,PABPC5,ZCCHC7,EP300,CDR2,TUSC3,EXTL2,CCND3,RB1,FLRT2,NAA11,TNIK,TNFAIP3,KRAS,FBXO11,CREBBP,TMEM30A,CD36,SLC6A1,CNTN2,PGR,DDRGK1 |
| 3.289e-02 | -3.41 | protein methylation | biological process | GO:0006479 | 52 | 22 | 18204 | 5365 |
SETD7,SNRPB,CSKMT,ETFBKMT,PRMT5,FAM98A,RAB6A,METTL18,SETD4,NTMT1,ETF1,EEF2KMT,SETD3,METTL21A,METTL22,EEF1AKMT3,TRMT112,PRMT2,LCMT1,VCPKMT,PRMT6,SNRPD3 |
| 3.289e-02 | -3.41 | endothelial cell development | biological process | GO:0001885 | 52 | 22 | 18204 | 5365 |
RAP2C,RAB1B,FOXP3,MYD88,F11R,MET,RAP2B,MSN,CLDN1,CLDN3,PDE2A,EDNRA,CLIC4,ICAM1,GSTM3,STC1,RAP1B,GPX1,HAPLN2,CCM2,RAB1A,RAP1A |
| 3.289e-02 | -3.41 | protein alkylation | biological process | GO:0008213 | 52 | 22 | 18204 | 5365 |
FAM98A,PRMT2,PRMT5,ETFBKMT,TRMT112,EEF1AKMT3,CSKMT,METTL21A,METTL22,SETD3,ETF1,SNRPB,EEF2KMT,SETD7,SETD4,SNRPD3,NTMT1,PRMT6,RAB6A,METTL18,VCPKMT,LCMT1 |
| 3.293e-02 | -3.41 | Cellular Senescence | REACTOME pathways | R-HSA-2559583 | 196 | 74 | 10285 | 3229 |
FZR1,NBN,SP1,H2AC4,H1-5,ANAPC4,IFNB1,UBE2D1,ANAPC2,MAPKAPK5,UBN1,ANAPC15,CDC23,H2BC9,RPS27A,EZH2,LMNB1,TFDP2,ANAPC11,CCNA2,TP53,H2AC14,H2BC1,H2AC6,CDKN2C,MAPK10,H2AZ1,ANAPC16,PHC1,HIRA,H2AC7,CDKN1A,MAP2K6,H2AZ2,MAPKAPK3,H2AB1,RBBP4,CDK6,H2AX,EED,HMGA1,H2AJ,MOV10,MAP2K3,ASF1A,H2BC12,AGO1,CDC26,UBA52,RING1,TNRC6C,CXCL8,UBB,RB1,H1-3,FOS,MDM2,H1-1,IL6,CDKN1B,CDKN2D,ID1,CDK4,CDC16,RBBP7,H3C1,TNIK,IL1A,H2BC14,H2BC11,NFKB1,H2BC17,TXN,JUN |
| 3.294e-02 | -3.41 | cell activation involved in immune response | biological process | GO:0002263 | 205 | 73 | 18204 | 5365 |
IL12B,TP53,TCIM,FCER1G,KARS1,IFNG,ICAM1,ITM2A,TNF,NOTCH2,FOXP1,IFNA10,VAMP7,MRGPRX2,IL6,IL21,CX3CR1,LILRB1,VAMP8,BCL6,HSPD1,FOXP3,CCL3,SYK,HMGB1,TLR4,BATF,CD40LG,TNFSF18,PYCARD,PIK3CG,FCGR2B,STAT6,FGL2,RNF8,CCR6,IFNA13,GAPT,RC3H2,NMI,TICAM1,SOCS3,TYROBP,PTGDS,IFNB1,VAMP2,EXOSC3,RAB27A,LCP1,ST3GAL1,CPLX2,PRKCE,CHGA,IRF8,SWAP70,CD1C,KIT,JAK1,CBL,MYD88,IFNK,SNAP23,LAT2,PSEN1,NBN,IFNA2,PTGER4,MSH6,PDP2,IRF4,IL2,LILRA2,IFI35 |
| 3.300e-02 | -3.41 | COMM | prosite domains | PS51269 | 10 | 6 | 12186 | 3388 |
COMMD6,COMMD2,COMMD5,COMMD9,COMMD3,COMMD8 |
| 3.300e-02 | -3.41 | CTLH | prosite domains | PS50897 | 10 | 6 | 12186 | 3388 |
GID8,MKLN1,RMND5B,MAEA,SMU1,RANBP10 |
| 3.300e-02 | -3.41 | METALLOTHIONEIN_VRT | prosite domains | PS00203 | 10 | 6 | 12186 | 3388 |
MT1X,MT2A,MT3,MT1M,MT1A,MT1E |
| 3.300e-02 | -3.41 | ACP3 (acid phosphatase 3) | protein interactions | 55 | 141 | 50 | 19454 | 5460 |
TPPP,CAPZA2,CCR1,FAF2,ERLIN2,FCF1,RNF115,CSE1L,DUSP21,SEMG2,MSMB,CALR,ERCC3,PDIA3,PTDSS1,XPO1,QPCTL,HNRNPL,CPLX3,PRNP,KLK3,LMAN1,SRPRA,EFNA3,STT3A,XPO5,STX17,UBAC2,LACC1,E2F6,KDELR2,ST7,FTH1,NUDT3,EMC1,FBXL4,AZGP1,SLC37A4,FOS,XPOT,PRSS1,UFD1,GABPA,ABHD12,TNPO3,ATP6AP2,SEC63,ESR2,GANAB,SEC61A1 |
| 3.300e-02 | -3.41 | PKN1 (protein kinase N1) | protein interactions | 5585 | 141 | 50 | 19454 | 5460 |
STX11,RIGI,SLC39A7,PICK1,DISC1,NEFL,TUBA1A,MAP2K3,TRAF2,BUD23,TOP3B,LRRC61,HNRNPL,FBXO32,MAP2K6,PSMB4,ARL10,CEP57L1,HOMER3,RB1CC1,NEUROD2,SSX2IP,SMAD4,CD81,INSYN1,CTNNB1,CERS6,HDAC5,MTDH,RPA3,PPM1G,CDR2,SMYD3,TOM1L1,TRAF1,TUBB,TRIM27,PNMA1,CCNF,TNFRSF1B,SERTAD3,HSP90AA1,ATG3,ZFAND6,RHOB,RNF40,CEP70,CCDC85B,MYC,SYCE3 |
| 3.301e-02 | -3.41 | H15 | smart domains | SM00526 | 13 | 7 | 9717 | 2575 |
H1-10,H1-1,HP1BP3,SHPRH,H1-6,H1-5,H1-3 |
| 3.302e-02 | -3.41 | VPS52 (VPS52 subunit of GARP complex) | protein interactions | 6293 | 189 | 65 | 19454 | 5460 |
VPS28,RNF41,EXD2,FAM50B,CXCR4,PPM1G,RPA3,TCP11L1,RPA2,WTAP,MFAP1,VPS54,FAM161A,PTAR1,BORCS6,LMO4,CDC42,THAP8,JAKMIP2,ESR2,OTUD6A,NFKBIB,SCNM1,CD79B,LMBR1L,ZMAT2,PSMC5,PSMD14,CCHCR1,GPR17,MYC,GORASP2,TBC1D1,SMARCE1,VRK1,RIGI,STX11,RAB1A,RAB4A,AQP3,VPS33A,EXOC3,AAMP,HGS,GFM2,TAB2,MRPL11,CLEC2B,FAF2,RAB1B,SPPL3,PPP1R18,CDC5L,CEP19,STX6,ARL10,TRAF6,ATP6V1D,NDC80,USP2,ATG9A,KXD1,TPM3,XPO1,INSYN1 |
| 3.307e-02 | -3.41 | presynaptic active zone | cellular component | GO:0048786 | 79 | 31 | 19108 | 5553 |
LPAR2,PPFIBP1,GPM6A,PPFIA3,KCNJ8,ATP2B4,STX1A,RIMS4,SLC32A1,CNTNAP1,STX11,CTNNB1,SYP,FZD3,STXBP1,PHB2,FLOT1,RAB3A,LRFN3,P2RY1,NTNG2,GRIA1,SNAP25,P2RY4,CTNND1,RIMS3,ADORA1,PPFIA2,CTBP1,CPLX3,GUCY1B1 |
| 3.323e-02 | -3.40 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032436 | 78 | 31 | 18204 | 5365 |
ZFAND2A,MDM2,PSMD10,DET1,DDRGK1,USP5,FZR1,CDC20,SUMO1,GSK3A,FBXO22,RCHY1,ZER1,CSNK1E,SUMO2,AKT1,BAG2,NOP53,STUB1,COP1,SOCS5,GCLC,CLU,HECTD1,PSEN1,DNAJB2,CSNK1A1,TRIB1,PIAS1,GABARAP,SOCS4 |
| 3.323e-02 | -3.40 | steroid hormone mediated signaling pathway | biological process | GO:0043401 | 78 | 31 | 18204 | 5365 |
CST11,PPARA,AR,RXRG,NKX3-1,PHB2,SRC,PGR,ERRFI1,FKBP4,PTGES3,NR2E1,YWHAH,RWDD1,TRIP4,TADA3,DDX5,PHB1,PADI2,ESR2,EGLN2,PAQR8,RBFOX2,WBP2,UBE3A,CALR,RNF14,OR51E2,ABHD2,TAF7,JAK2 |
| 3.323e-02 | -3.40 | nuclear ubiquitin ligase complex | cellular component | GO:0000152 | 47 | 20 | 19108 | 5553 |
ANAPC15,CDC23,CDC20,CBX7,ANAPC11,BRCA1,RING1,PCGF2,ANAPC13,PCGF6,PCGF3,ANAPC4,MAD2L2,PHC1,FZR1,ANAPC16,CDC26,ANAPC2,UBE2S,CDC16 |
| 3.331e-02 | -3.40 | NBN (nibrin) | protein interactions | 4683 | 173 | 60 | 19454 | 5460 |
UBE2A,MSH6,MDC1,KRAS,PELI1,H3C1,DNAJC30,VRK1,FGF12,RNF126,RNF8,UBE2B,H2AX,EEF2,TP53,CDK9,MDM2,CDC5L,NAT2,SUMO2,UBE2N,MED4,DDX1,POU5F1,TOPBP1,TUBG1,UBE2D1,HDAC6,DPP4,USP2,HMGB1,STAU1,DDX5,EP300,BAP1,RFC4,RPA3,XRCC5,PML,GSTP1,PPARG,LMNA,RPA2,TPT1,ESR2,CTSB,TRIM29,TAX1BP1,DYNLL1,BMP1,PRMT5,MCPH1,DCLRE1C,LIG3,HSP90AA1,FAM219A,CASC3,RBBP8,BRCA1,CFAP161 |
| 3.331e-02 | -3.40 | NFYC (nuclear transcription factor Y subunit gamma) | protein interactions | 4802 | 173 | 60 | 19454 | 5460 |
NFYB,GTF2H4,ZSCAN1,XBP1,LMO4,RFXANK,MED23,ZMYM6,JUP,XRCC5,SNAPC1,BAP1,DR1,PRCP,CXXC1,ZDHHC17,NFYA,MYC,KANSL3,SP1,PTTG1,SMAD2,MID1IP1,VPS72,PHF12,TRIM27,TUBB,RFXAP,TAF11,ESR2,SP4,ELF1,TFCP2,HGS,NUPR1,FAM168A,BAG2,HAPSTR1,KRAS,SNRPG,PAX6,NFKB1,GAPDH,CTNNB1,FCGR2A,FKBP4,SKIC8,CDC23,CIART,SP2,SSBP1,SMAD3,GATAD1,RFX5,NXT1,CORO1C,SNX2,TOP1,ASNSD1,CACYBP |
| 3.334e-02 | -3.40 | ACOT9 (acyl-CoA thioesterase 9) | protein interactions | 23597 | 157 | 55 | 19454 | 5460 |
NYAP2,NUP35,FBXO32,OCIAD2,GATD3,AGR2,SNRNP70,SHC1,RHOG,POU5F1,ATP5MG,GRSF1,DDRGK1,HDAC6,LAMP3,UBE2A,SFXN1,PSME1,RAB1A,HSPD1,COX8A,RABGGTB,PDHA1,UBE2B,SKA3,RNF181,SLC25A20,PREB,CYB5R1,RPGRIP1L,TXN,MGST3,PRDX2,ESR2,DLST,CYB5R3,CCNF,RHOB,F9,UBE2H,CUL3,SLC25A1,STAU1,NF2,HSCB,COIL,ATP5MK,RPA3,HADHA,HSPA8,RPA2,SCLT1,KRT7,DYRK2,BET1 |
| 3.336e-02 | -3.40 | N (ORF9a protein;nucleocapsid protein) | protein interactions | 1489678 | 94 | 35 | 19454 | 5460 |
MAP4,MAPRE1,PFDN2,HNRNPA1,CSNK2A1,CMSS1,CREBBP,MOV10,HMGA1,SURF6,PPIA,FAM98A,CAVIN2,UBE2I,PRKRA,RTRAF,GSK3A,CSNK2B,AP2M1,CTTN,APOBEC3G,SMAD3,RAD23B,CCNA2,EEF1A1,CDK4,CCND1,TPD52,G3BP2,G3BP1,RTCB,SEPTIN7,HSPA8,PABPC1,SNIP1 |
| 3.336e-02 | -3.40 | SHPRH (SNF2 histone linker PHD RING helicase) | protein interactions | 257218 | 94 | 35 | 19454 | 5460 |
SIN3A,ZNF330,UBE2N,MYBL2,EED,GATAD1,HNRNPL,SHPRH,FBXO22,BRMS1L,RBBP4,UBE2V2,VIRMA,CUL3,YWHAG,PPIB,DDRGK1,UBE2D1,H2AC4,DTL,PML,PCNA,RBBP7,H3C1,FBXW7,MBD3,UBE2A,PHF1,PTGES3,MTA3,SAP30,BORCS6,EZH2,MTA2,FDFT1 |
| 3.336e-02 | -3.40 | UBE2W (ubiquitin conjugating enzyme E2 W) | protein interactions | 55284 | 94 | 35 | 19454 | 5460 |
RNF8,TOPORS,POLR2C,RNF103,ZNRF1,UBR7,DDX39A,UBE2W,RNF26,TGIF2LX,RNF5,UFM1,RNF115,RNF10,RMND5B,BIRC2,TRIM5,RNF167,TRIM3,TNNC2,MARCHF3,CBL,TRIM23,RNF152,BRCA1,MUL1,BFAR,MARCHF5,TRIM8,RNF14,TRIM35,CDK6,TRIM27,EED,STUB1 |
| 3.336e-02 | -3.40 | ASB6 (ankyrin repeat and SOCS box containing 6) | protein interactions | 140459 | 94 | 35 | 19454 | 5460 |
NF2,XPNPEP1,PDRG1,RNF41,COPS4,ASB3,S100B,SLC25A5,FAM168A,RPRD1B,RNF7,POLR2D,E2F6,POLR2G,POLR2C,ZBTB42,RPAP2,TCAP,DCUN1D1,COPS7B,POLR2I,POLR2B,RPRD1A,METAP2,POLR2L,COPS2,ZNF655,POLR2F,HSP90AA1,HSPB1,COPS7A,UBXN6,CUL3,COPS5,ELOC |
| 3.346e-02 | -3.40 | ubiquitin-like ligase-substrate adaptor activity | molecular function | GO:1990756 | 57 | 24 | 18094 | 5411 |
FBXW11,CDC20,SH3BGRL,KCTD17,FBXO3,KLHL15,PCMTD1,SPSB1,APPBP2,FBXO42,WDR77,SKP1,FBXO9,KLHL22,FEM1C,FBXL19,FBXW7,DET1,FBXO7,FZR1,FEM1A,KLHL25,KLHL3,FEM1B |
| 3.351e-02 | -3.40 | L3MBTL3 (L3MBTL histone methyl-lysine binding protein 3) | protein interactions | 84456 | 119 | 43 | 19454 | 5460 |
MYC,PIK3R3,MORF4L1,CUL3,NTAQ1,RHOBTB3,SNRPB,TBC1D1,CRLF3,ZNF330,ZMYM2,CSNK2B,PHF21A,APEX1,PLEKHF1,SUFU,PRMT2,KLF12,LMO4,RPA2,MFAP1,RPA3,PML,KDM1A,FXR2,COIL,XPO1,GAS8,DCAF5,SKIC8,LHX2,TRAF3IP3,POLR2L,PPP2CB,PLEKHF2,SOX2,EZH2,NGB,RBPJ,OAZ3,LSM4,H3C1,PAX6 |
| 3.352e-02 | -3.40 | membrane coat | cellular component | GO:0030117 | 97 | 37 | 19108 | 5553 |
AFTPH,AP2S1,AP1G2,VPS39,VPS33A,NECAP1,COPE,DIPK2A,KLHL12,NECAP2,NCALD,SEC13,TBC1D5,AP3S2,AP2M1,KCNQ5,PICALM,SYNRG,CHMP1B,COPZ2,CHMP2A,VPS18,ARL6,TMED7,AP2A1,AP1M1,AP1S2,AP5M1,CIDEB,SGIP1,CLBA1,AP5S1,SEC23A,SCLT1,SAR1B,TMED3,ARCN1 |
| 3.352e-02 | -3.40 | coated membrane | cellular component | GO:0048475 | 97 | 37 | 19108 | 5553 |
AP5S1,SEC23A,SCLT1,SAR1B,TMED3,ARCN1,AP5M1,SGIP1,CIDEB,CLBA1,CHMP2A,COPZ2,VPS18,ARL6,TMED7,AP1M1,AP2A1,AP1S2,KCNQ5,PICALM,SYNRG,CHMP1B,AP2M1,NECAP2,NCALD,KLHL12,SEC13,TBC1D5,AP3S2,VPS39,VPS33A,NECAP1,COPE,DIPK2A,AFTPH,AP1G2,AP2S1 |
| 3.353e-02 | -3.40 | GSK3A (glycogen synthase kinase 3 alpha) | protein interactions | 2931 | 456 | 146 | 19454 | 5460 |
AURKAIP1,MAP1LC3B,RPL15,PPP3R2,GGCT,CCT5,TOPORS,TBC1D4,SLC25A11,VTA1,GSKIP,CTNND1,KPNA2,THRAP3,HNRNPK,SCML1,HDAC6,FCGR2B,EDC3,SSX2IP,RPS2,ECD,MCL1,ADD1,TRAK2,RPL32,MYL12A,CAV1,EIF2B5,SIPA1L1,SYNRG,SF3A1,PDCL,PRKCA,CDR2,ACACA,HECTD1,RPA2,H2AC7,PICALM,PRKCB,H2BC12,SQSTM1,RPA3,INPPL1,HSPA5,PPP1R2,RPS15,RPL4,ARHGAP21,RUNX1,PRKACB,PPP1CC,TUFM,AR,NONO,AKT1,SMARCA5,RPL7A,FAM193B,LRP6,SMAD2,CCDC174,TLR9,RC3H2,GSK3A,SRP54,EIF2S2,RPS20,GAB1,CREB1,CTNNA1,CTTNBP2NL,PRSS37,SRPK2,BCCIP,CEP97,LDHA,EIF4H,RPL29,ACTN4,SPG21,OTULIN,RPL18,EWSR1,MAP3K11,SLC25A5,PABPC1,MAEA,G3BP1,YWHAH,YWHAG,PPFIBP1,CTNNB1,HMBS,RPL6,RASSF8,VCPIP1,BCL2L1,DICER1,PPP3CA,CAMSAP2,YWHAB,AK2,MAGED2,TNIK,ZNF664,SRSF1,CNTROB,HSP90AB1,DHX15,AFTPH,SNX2,PPP1CB,ALKBH3,TANK,FBXO42,SUFU,ZC3H14,SLC25A3,TXNL1,DDX5,PRKD3,ZDHHC17,DDI1,SKP1,FXR2,EEF1G,SAMHD1,BTF3,PSMD1,MYC,SFN,HSP90AA1,RPS26,KIAA1191,H2AZ2,CHTOP,POLR3B,RPS9,GTF2F2,LMBR1L,RPL19,RPL10,STAT2,STAT1 |
| 3.358e-02 | -3.39 | positive regulation of protein-containing complex assembly | biological process | GO:0031334 | 199 | 71 | 18204 | 5365 |
TLR6,CCR7,HSP90AA1,ISG15,TPPP,CRBN,CCL11,CSF2,TLR4,PYCARD,CDK5R1,PSRC1,STUB1,PTPN22,SYK,CLU,SRC,CALY,CLEC7A,BAK1,MAP1B,P2RY12,FERMT2,BAX,RPS3,NCK1,TFRC,SLAIN2,CCL24,NEK7,FCHSD2,TNF,IFNG,TP53,ARF6,CXCL13,DLG1,MSN,CDC42EP3,MET,CCL21,CDKN1B,CDC42EP2,TPPP3,MAPRE1,MYD88,CAPG,CD36,VEGFA,CDC42EP4,PRKCE,DRG1,FAF1,RAP1B,LCP1,CAV3,CTTN,SUMO1,ATAT1,NCKAP1,LGALS3,TPPP2,IL5,TIRAP,MECP2,WNT10B,ARPC2,MAVS,SH3GLB1,NR1H2,CAND1 |
| 3.359e-02 | -3.39 | Lipocalin | interpro domains | IPR002345 | 12 | 7 | 18521 | 5414 |
LCN15,LCN1,LCN8,LCN6,PTGDS,LCN12,PAEP |
| 3.359e-02 | -3.39 | TGFB_receptor | interpro domains | IPR000333 | 12 | 7 | 18521 | 5414 |
ACVR1B,BMPR2,TGFBR2,ACVR1,ACVR1C,BMPR1A,BMPR1B |
| 3.363e-02 | -3.39 | ribonucleoside triphosphate phosphatase activity | molecular function | GO:0017111 | 736 | 243 | 18094 | 5411 |
RAB14,RAN,RAB1B,RAB5C,EIF4A2,GNAI2,ARF4,PSMC3,DDX42,ABCF1,MFN1,RAB28,RAB27A,TPPP,RASL10A,GTPBP2,RAB6B,TOR3A,MCM6,MX2,GNB1,RUVBL1,DDX4,IFIH1,RFC2,RND3,RUVBL2,GNAI3,DRG1,CCT8,RGS1,MORC2,CLPX,EIF5B,RAP1B,EEF2,TWNK,ATP1A2,COQ8B,ARL11,ATP5F1A,MRAS,RAB9A,ATP6V1G2,RAB3B,RRAGB,GNG5,MCM4,RAB35,XRCC5,RGS5,ATP2B4,GFM2,HSP90AA1,AGAP1,RGS6,TOR1B,ABCC5,ATP1A1,RAB18,RAB3D,RAB1A,KIF1C,DRG2,ERAS,CDC42,RIT1,ARL4A,RAP1A,GNGT2,GNAQ,PSMC1,DHX15,SMARCA5,RAB29,DHX38,RAB39B,RHOJ,RAC2,RAB5A,RASL12,ARL5B,HSP90B1,ARHGAP5,RAB9B,G3BP1,RHOH,ARL10,RHOG,PSMC4,NKIRAS2,HRAS,GNG11,RAP2A,RGS10,GNB3,RAB19,RAB33B,TCP1,ACTB,ABCE1,TRIM23,GNAO1,RALA,DHX16,RFC4,KIF2A,HSPD1,ARF1,NTPCR,MTG2,ATP6V1G1,RGS19,RRAS2,TOR2A,RHOU,HSPA13,DDX5,OLA1,RAB3C,VPS4A,RAB11A,TUFM,NLRP1,NKIRAS1,HSPA14,RAB2A,RAB40AL,CCT2,RRAGA,ABCC2,HSP90AB1,ATL1,RASL11A,RAB33A,TUBA1B,RAB8B,SRPRA,DDX46,TOR4A,ARL15,CLPB,DNAJC27,EIF4A3,ATP8A1,RASL10B,RAB6A,DHX9,ARF6,VPS4B,KRAS,GTPBP1,PSMC5,RABL3,ENTPD4,RAP2B,KIF3C,RHOBTB1,SEPTIN6,ARL6,ARL4D,RFC5,ABCB1,CCT5,ENTPD3,ABCB9,RIT2,SMCHD1,EEF1A1,SRP54,RIGI,GNG3,MCM3,RAB31,RAB37,DIRAS3,CCT7,GNAZ,MMAA,GNL1,RAB4A,CFTR,ATP6V1A,RASD1,TUBB4B,CLU,SEPTIN7,RAB30,RHEB,GNA14,ATP5F1B,BCS1L,RERG,DDX1,MCM8,MLH3,DIRAS1,AGAP2,DDX39A,SMC4,DDX39B,TUBB,RAB11B,KIF3B,DNM2,RAB23,RALB,ATP2C1,RFC3,IFT22,KATNAL1,GNA11,MX1,DDX50,SHOC1,HSPA5,GPN2,ALPL,ATAD1,MORC4,RAP2C,MOV10,NLRP3,MMUT,ERCC3,SAR1B,MTG1,ATP1A3,DDX23,RHOBTB3,RND2,RGS2,RHOB,RAB22A,RAB13,DIRAS2,RABL2B,RAB32,RAB3A,HSPA8,ABCG2,GFM1,GNG10 |
| 3.365e-02 | -3.39 | mitotic cytokinesis | biological process | GO:0000281 | 81 | 32 | 18204 | 5365 |
SPTBN1,BIRC5,CHMP2A,KLHDC8B,ARF1,SNX18,EXOC2,EFHC1,ROCK2,USP8,STAMBP,ROCK1,CHMP2B,CNTROB,RTKN,VPS4A,CHMP1A,SEPTIN6,TRIM36,EXOC1,CHMP1B,EXOC3,CHMP5,RACGAP1,VPS4B,EXOC5,RAB35,EXOC8,CHMP4C,SNX33,CFL1,RHOB |
| 3.370e-02 | -3.39 | frontal_lobe | COSMIC cancer mutations | frontal_lobe | 71 | 28 | 16828 | 4835 |
AKT1,IDH2,NAPA,GNA11,CTNNB1,SMARCB1,EZH2,PIK3CA,MSH6,HRAS,ATPAF2,CDKN1B,GNAQ,TCOF1,SYK,NF2,CDKN2C,PPP2R1A,FBXW7,KIT,MET,TP53,PTEN,FASTKD5,FGFR1,IDH1,KRAS,ESYT1 |
| 3.374e-02 | -3.39 | NCOA1 (nuclear receptor coactivator 1) | protein interactions | 8648 | 138 | 49 | 19454 | 5460 |
NR1I3,RAP2A,EP300,FOS,HSPA5,PRMT2,SUMO1,CCND1,STAT6,PPARG,TRIM27,TRIM24,CBX5,UBE2L3,NR1I2,RORB,VIRMA,ESR2,STAT5A,NR1H2,SMARCE1,AR,CREBBP,CSK,SLX1A,ASCC1,BRCA1,TRIM21,RABGGTB,GPSM3,TRIP4,PAGR1,EGR2,PPARA,PSMB9,JUN,VDR,TP53,EZH2,LDLR,GTF2B,SMAD3,PGR,KCTD3,COPS5,NR2F6,YWHAH,NFKB1,NR4A2 |
| 3.375e-02 | -3.39 | skin | COSMIC cancer mutations | skin | 16247 | 4688 | 16828 | 4835 |
ATP2B4,IFNK,SIGMAR1,DUSP9,CFDP1,RBPJ,MRPL17,CXCL9,LRRTM1,RNF152,UQCRC2,KLHL28,EDEM3,TPPP2,EGLN2,RETN,MCPH1,NKRF,ZDHHC8,EDDM3B,ISOC1,LRAT,TCOF1,PSMB11,HSP90B1,FBXL3,QRSL1,VIPR1,RPS15,ASB1,ACTN4,GATAD1,PTGES3,RGS10,SDS,DIRAS1,PRRT1,GINS4,ABCE1,CYP7A1,DCUN1D1,RPS24,MCM6,NUDT4,ITM2A,DCK,EAF2,ADH1A,AMACR,NR0B1,FITM2,TRIM22,CYB5R4,SPOP,DEFB129,CASP4,SLC15A2,SLC52A3,B2M,SASH3,TIFA,TPRA1,MYH1,IFT57,VDAC2,DCTN6,ACVR1,BCL2L1,YWHAG,ICA1,SCAMP5,CST3,PLEKHO2,LYZL4,LRRC8C,DMAP1,NOP16,ZNF32,KCNB1,TNFRSF9,OR7D4,PEX26,BAZ1B,OR4E2,PAQR8,PPP1CC,DPPA2,PMP2,EIF5A2,PI3,SMURF1,STX16,FKBP4,PSKH1,CCL1,NGDN,CTRB2,PRR19,ANO3,UBE2N,TAF2,SGMS2,NCSTN,ANXA7,SSR3,SLC38A2,PLAC9,HS3ST5,GPR22,P2RY10,NKX6-2,QSER1,MYO1B,SLC2A1,GPT,SRSF12,SLC6A1,GPN2,TLR4,ADRB2,GLYATL3,VAMP1,COL3A1,CBX7,PAK1IP1,PSMB2,CX3CL1,FGF22,TNNI1,PEBP1,ADRA1A,PTGDS,IL5,CTTNBP2NL,VDR,SNX3,TBC1D5,CLRN1,DBH,NDN,SIKE1,ARMC6,CHCHD1,PPIC,MMAA,NCOA5,RUVBL2,GOSR1,IGF2BP1,CCDC167,GIPC3,DBNDD1,RAD1,NGRN,NFE2L2,POLR2C,GNAQ,LPAR6,PITPNB,USP46,SMAD2,NMRK1,TAF11,PKIB,EMX1,UBTD2,HNRNPL,IREB2,CD80,RABIF,ADRM1,CNOT7,CRMP1,TCP1,KCNH8,HPS6,OR2F1,CH25H,TMEM19,SLC35A5,LGI1,CDC5L,MMP14,RAB6B,ATP6V1G2,MRPS35,MRPL41,RALYL,MRAS,CYP1B1,MDH1,ELK1,FAM168B,RAB28,DDI1,COPS4,KCNK17,ZGLP1,ANGPT1,NCALD,WDR6,ACOT6,IL12B,HSDL1,KLHL23,CBL,LHB,INSIG2,DEFB124,G3BP2,OR10G3,OR2J3,DCLRE1C,SUMO1,KDM2A,POLD2,KLHDC8A,ZNF574,EXOSC8,TSPAN7,PIK3R1,ACOX1,FADS2,F7,IFT52,CDK2AP2,IGSF21,PRPF18,CAV3,EPHA2,FGF7,MAPRE2,LMBRD1,UCK2,ITGA2,SLC31A1,DIO3,COX6B1,SRSF1,CAPZA1,CLDN6,NEK9,TNFSF10,FMO3,CDK5RAP3,OR4N2,MNAT1,STAC3,FAM3A,ACHE,CSE1L,UBE2B,IRF2BP1,FBXO3,GUK1,AGAP2,STX1A,PICK1,NTRK3,TSSK1B,CCAR1,ELOF1,PAQR4,GGCX,BOLA1,FAM76B,RNF146,SAP30L,PDIA2,ESAM,HSD17B3,PCCB,NEO1,CHMP1A,RLN3,ANKRD50,SLC35C1,NXT1,TMEM97,MED13L,NSDHL,IDH3A,PATE4,JRKL,RFC5,MPST,PSMC4,ASRGL1,POU3F4,MFSD6,MADCAM1,GKAP1,UBL4A,SERPINB11,RPL17,HDAC5,FABP12,FGL2,PI15,HECTD3,YES1,RNF208,GRIA1,CRYGA,CBLN3,VAC14,SLC25A42,CLIP3,GAPDH,NELL2,NDUFB5,TM2D2,SUB1,OR52W1,SCN1B,CDC40,SLC39A13,CYP4F12,CPE,DCAF4,ARHGEF6,PCSK2,MYT1L,USP2,CYB5R1,LRTM2,NTF4,POC1B,GPHA2,DTD1,DEFB115,SSBP3,NXPH3,TACO1,NSA2,WFDC5,CAMK1,NOL7,SNX2,ERP29,PTTG1,BCCIP,TM4SF1,IRF2,MCAT,NUDCD3,SEC63,NOVA1,INPP5K,SRGN,KLHL32,RAB31,STC1,OR8K1,DYRK1A,DRP2,EIF2D,AIG1,NEUROD6,INSM2,TSHR,SLC25A20,GTPBP2,C1GALT1C1,LGI3,EIF2AK2,TRIM27,COPS2,SLC25A45,NOSIP,NR4A2,KCNF1,UBXN6,NME2,CD4,SFXN1,UBAC2,RALGAPA2,PPTC7,PCK2,ACO1,GANC,TRA2A,SATB1,PRMT5,BEND6,G0S2,OR5I1,TAS2R46,JUP,EXT1,ALKBH3,MSRB3,CTBP1,EIF3E,CDC42EP4,FASLG,KLRD1,ZMYM2,OR4N5,SLMAP,CFL2,SNX5,EXOSC4,DNLZ,BUB3,MGAT4B,DCAKD,PLP1,XPNPEP1,RNF41,ZNF7,PHF1,LMNA,DCUN1D3,CYP3A5,CD52,IRAK1BP1,TMEM74,PLXNC1,UGT2A3,TAAR6,BLOC1S3,PHC1,EPYC,SELENOT,GRAP,TMEM184C,NOB1,MED17,DCP2,BAG2,PHF12,GEMIN7,ZBTB33,PACRG,TAS2R16,OSGEPL1,HP1BP3,MCM8,UTP15,GRM8,EIF4E2,IL13,RIMS3,CUTA,RMI1,DLAT,CAMK2N2,PNMA2,ANKRD49,MT1A,CD38,COIL,ZFP64,TUBB,LSM14B,STX10,SFTPA1,FAM50B,SF3A1,GNAI3,PSPC1,TRAPPC10,MCHR1,SFN,ZNF596,RING1,RBFOX3,SSR1,AVPI1,NETO2,SMARCD3,DISC1,CHID1,OVGP1,EMP2,LILRB1,EHHADH,GLRB,TRIM46,GPX2,HCLS1,DNAJC1,TIAM1,THAP2,IL4,PAQR9,TRIM63,FAM110B,STBD1,VPS4B,TMEM160,FOXP3,LDLR,OR7E24,RBM42,PPP5C,RHBDD3,GSTA4,MAD2L1,CA10,MAP2K6,RASGEF1C,PCMTD1,TOMM7,SEPHS1,ANAPC11,LACRT,GNB1,CDC16,ASB8,INPP5E,TREML1,SOCS4,MED9,GHR,MED30,CXCL11,SLC6A8,CUL2,PYCARD,PPIA,FBP2,ZDHHC15,RSPH1,MAP3K12,COX19,TMOD3,SOX3,RPS4X,RPS29,SKA3,ALKBH2,DEFB121,NCKIPSD,CTSB,LRTOMT,NFE2,POGK,SLC16A4,HNRNPA1,ACOT8,TRIM52,LECT2,NAT9,PGM1,HADH,RPL8,IKZF2,CLEC9A,MEF2B,WASF3,PRKCQ,GABRG2,TFIP11,ZSCAN5A,VSTM2A,B4GALT7,SMCHD1,MRPL40,CD1E,GTF2IRD1,TRMT11,TMEM88,CLCA1,CNOT6L,KIF3B,HTRA1,MITF,LCA5L,IKBKB,HELLS,TRIM8,FAHD1,RPL13A,TAGLN2,HRAS,SYT4,WDR20,PHF23,COX10,BSCL2,CDK8,MTX2,MAEL,TFG,CYB5A,ELOVL3,CRB3,DHRS7,VLDLR,VAMP3,WDR83,CLVS2,NLRP6,CHRDL1,PIP5K1A,IZUMO1,PEG10,ZCCHC17,PSMB6,BAHD1,DHRS7B,PTGER4,TOMM20,TRAF3IP2,TERT,SLC35B4,MKKS,LANCL1,PIK3R3,MORC4,CISD1,CD2AP,SRC,VPS28,MPZ,KRTAP12-4,IFNA2,IDH1,TUFM,OR51M1,GNG13,RASL10A,METTL6,CHST11,HMX2,UNC50,ICAM3,LUM,CCDC85B,SEMA6C,NEUROG2,MTMR6,SH3BP5L,MED31,NAA50,FCGR2A,CELF6,YTHDF1,RPL7,RGS19,RCE1,MGAT1,RASGRP3,ENTPD3,CDC42EP3,RNF115,MCM3,SECISBP2L,RAB33B,IFIT2,HNRNPD,PDCD1,MS4A7,KCTD15,SLC25A11,PAFAH1B1,CKLF,CCT7,PSMD12,LIN7B,PCDH9,ZRANB2,ARHGAP25,DES,RIC3,TCAP,MYOZ3,EIF4E3,SPATA6,FAM162B,GLT8D2,VTI1B,ARHGAP5,CCL20,MRPS7,ZNF575,CD248,ZNF668,RSRC1,RPL35A,MSL2,FLCN,CXCL12,SLC25A28,SLC39A3,SERPINI1,PPM1D,IDO1,KLHL12,FTL,LRIF1,TMC7,STIM1,GRPEL2,FLRT3,TNFSF13,UTS2,RRN3,DHPS,NIF3L1,TMEM14B,GNG5,IL15,MRPL10,YBEY,NTPCR,PNOC,CYP27B1,HMG20A,BTF3L4,ARL6IP6,TLE1,NUP50,IFNGR1,TPGS2,NDUFA2,RIMS4,OSGEP,SCN3B,NMI,LRRC57,PLSCR4,MOG,POMT2,POLR2F,PADI2,SCPEP1,OGN,NSFL1C,TMEM190,KBTBD4,PNO1,CYP2F1,PSME1,CLVS1,FAU,RAB22A,AK5,GTF2E1,TNNC2,OR8I2,SMC4,FCHSD2,OR5AP2,MOSPD1,ELAVL2,UBE2M,PIR,SLC6A12,TRIM10,UBE2E3,AGAP1,FXR2,AKR7A2,AURKAIP1,FOXP4,RNF126,TMEM182,LDHB,RPF1,GPBAR1,ITGAV,USP5,MXI1,FERD3L,LRRC1,NUP37,TCEANC2,TM9SF4,FZR1,RILPL2,DRD1,SMAD4,SLC22A8,SLC1A3,GPR85,PPP2R3A,BAK1,ATP1B1,ELK4,FAIM,SMARCA5,CNPY4,VKORC1L1,DRAM1,IL1RAP,LGR4,HECTD1,DYNC1I1,FGF10,TLR2,RERE,GRID1,CCDC122,PPP1R12A,IL6,HSCB,SYVN1,CES5A,TFEB,ARMC1,GABRB2,TBC1D4,UNC119B,XXYLT1,GIMAP4,MORN4,DNTT,OSBP,GOLGA5,RLN2,OR9K2,NDUFS3,HPGDS,SSRP1,TTC32,PAIP1,OCIAD2,TWSG1,MED21,PSMC1,TAS1R2,MFN1,ZBTB2,DAD1,NPY,SLAIN2,CAMLG,PLA2G12A,CNR1,SST,COMMD5,PFDN4,GABRA2,RAB30,RSAD2,NICN1,TMEM208,GGT7,GRXCR1,DNAJB2,PSMA2,EFHD2,PPP4C,PPIG,NRBF2,UBFD1,GSTM2,NAA35,PTPN22,SOCS3,FOLR2,PDRG1,DCUN1D5,FNDC9,PPIH,HDDC2,CD1A,HSP90AA1,LPAR1,CHCHD3,NFKBIB,MMP21,ZNF280B,EID1,EPO,CCSAP,RPS13,UGDH,AP2S1,PGAM1,RNF121,MATN4,DDAH2,ACTB,ZER1,CNTN1,GNB4,CPNE1,RFC2,SNX18,TYW3,LNX2,E2F4,MYD88,MRPL52,FCF1,CD1D,PLN,GFI1,GLYAT,TMEM209,FLRT2,DEDD,CDC42EP2,PPM1G,NRSN1,HOXB1,OR4K17,TMUB2,RHOB,MAX,YIPF4,CSNK2B,MRPS18A,C1QL3,VMO1,TRIM11,PROM1,RBM18,QPCTL,TOPBP1,MTG1,RPL3,GLRA1,G2E3,CDC123,UCK1,GNAI2,CD46,GABARAPL1,TRMT1L,KCNMB1,CBX5,MYCT1,ARL10,FAM118B,MAGOHB,TM9SF1,SVOP,COMMD2,PEX5L,AZI2,ARL15,ILVBL,EGFL8,DNAJC25,NUDT5,GSTK1,NAE1,RPS11,GTPBP1,KCNMB2,TMOD1,TNFRSF14,TXNRD1,KATNAL1,CENPP,RP2,STX12,FBP1,GZMK,TMEM199,CNPPD1,NLRP1,ATP1A1,TGIF2LX,CRKL,STARD13,B4GALT1,AOX1,PSMA5,DNAJB6,ZFAND2B,KDSR,CD1B,LRRN1,GCC1,DNAJC27,SCYL2,COG1,RPL10L,PHKA1,ALG2,MBLAC2,DNAJC10,RGMA,RAF1,IRF6,GPNMB,PRRG1,SAT2,GTF3C3,RNF14,CSTB,KLHL7,MCHR2,ZNF330,DET1,OR51A4,DDX5,EIF4A3,ADNP,RAP2C,UBN1,TPSG1,UBE2F,FOXP2,CYP17A1,SLC22A12,SNAPC2,CCHCR1,RPS5,SLC1A1,PDE9A,CCDC71,CYTH1,FGF12,SEC62,RIMKLA,EXOC1,GPX4,BAALC,FKBP10,PHAX,TMEM106A,ANGPTL2,LY6G6C,RHCE,ELAVL4,RPS27L,SEC61A2,STK11,TESK2,COMT,GOLPH3L,TNNT2,TP53INP2,GPSM3,LAMTOR3,ZNF175,SNRPD3,ARL4A,ARFGAP3,LITAF,LRRC4,DRAP1,MEF2C,FUT1,DOHH,BAP1,PLAA,RPRM,GPR26,IL1B,SYS1,STAT1,ZNF507,PAX6,MRPS33,LMBRD2,LMO3,UGP2,EIF2S1,HEXIM1,DPP4,PRDX2,MSX1,CHRM1,IL3,DLG1,P2RY11,TLR6,RPN1,CD151,KCTD9,SP4,OR4N4,ZBED4,DYNLT3,WASL,CD79B,SDC4,GOLGA7,REP15,TMCC1,RAB14,BVES,PC,RAB5A,APOBEC3D,NEK2,ZNF526,NDUFV2,NDUFB7,F10,KCNA3,SSBP1,PTN,TMEM31,CDK5,GNG3,MRPL51,PATE2,RNF26,OR10G2,RAB13,SELENOF,MAP1LC3A,SNAPC5,RPP21,NDC80,PLAC8,CYB5R3,SLC25A23,ODC1,DSN1,ZC3H15,SFTPC,SLC6A4,PDSS2,YIPF5,TOB2,FNTB,NME4,OAF,HEXB,PPFIBP1,SYNGR4,CYTL1,NDUFA4,SLC45A3,SHMT1,DRG2,THBS3,TRUB1,CALR,SNAI2,MAMDC2,TSG101,ADCY2,PKIG,MOBP,PHB2,TTC1,MMADHC,BMP1,NR1H2,PRPF31,LEPROTL1,TMEM95,SPOPL,SYT2,TBC1D24,ST6GALNAC3,EDNRA,PSMD14,THY1,TESC,YWHAB,ZNF692,SLC25A44,CDSN,SESN3,ZCCHC12,ARRDC3,EEF1G,LRWD1,SLC25A17,NFYB,TPBG,KCNQ5,PDE1A,DAPK1,LILRA1,STXBP6,TPT1,SNCB,ATL1,RRAS2,POLR3F,RPL35,FRS3,RERG,MICB,TOR1AIP2,NUP153,STOML2,OTUD6A,GPR15,PPARA,COPS7A,RNF20,GTF2A2,ACTL9,DUSP26,EYA3,ANAPC13,CNTNAP1,TMEM176A,HDAC6,PBLD,RNF39,ASB3,CHMP5,ZMYM4,BTG1,AGPAT1,GNA14,CXCR6,CISH,TXNL4A,NANP,TSC22D3,USP14,FAM81A,EHD4,ZNF511,CEND1,STAMBP,HNRNPF,SLC25A1,MAGEB10,CXCR3,HOMER3,TAF1D,SHPRH,KCNJ10,SLCO3A1,ADORA1,SPATA2,OR4K2,GRM1,PCGF6,SLC29A1,SURF2,GJA1,MAGED2,CCNA2,TM4SF20,RNF222,REEP4,AASDHPPT,YWHAZ,STARD3NL,ICAM2,ABHD8,OR8H3,SLC8A1,LSM14A,CAPN2,BOK,TNR,OR6X1,TM4SF18,PRSS23,GPR17,GPC1,PLCB1,ZNHIT6,ING2,ARL2BP,CHRM3,TSR2,SPP1,FAM149B1,FRZB,CDK12,DLK2,PLG,DMTF1,TNFAIP6,FBXW7,PSMB7,GXYLT2,KCNJ2,CTU1,EPHA4,NPY1R,GCLC,PSMD10,TNNI3K,CPLX3,ARL4D,LIAS,CITED1,CTXN3,ZBED1,DPH5,PNMA3,RB1,TRIM29,CORO6,OIP5,GSTA2,TMEM127,HCAR1,MCL1,FAM53C,ALG11,NDUFA1,DDAH1,GPR35,HFE,CREBZF,PAQR3,JAK2,PROK1,NT5DC1,MRPS18C,TRIM36,TNKS2,LILRA2,LY6H,HSPB2,COMMD9,CBLN1,STK3,DCAF12L2,PLSCR1,PTP4A3,CSNK1G3,RAB39B,MRPS11,AKR1C1,SREK1IP1,CNTROB,FTSJ1,ABHD10,HUWE1,CPLX2,PRND,EIF3G,MEPCE,CCIN,UBE2L3,TTPAL,PMAIP1,PDE4B,SPEM1,CYP3A43,CAV1,B4GALT4,RPS2,YIPF3,LXN,TCEAL8,NDUFC2,TMEM205,TRIM34,ITGB5,RGL2,BLCAP,ICOS,NINJ1,CDC7,MPPED2,PRL,FBXO8,NDST3,OLR1,SLC19A3,SGMS1,RBBP8,MGAT4A,ATAD1,TRIM45,DUSP21,IGSF11,CYP2C9,MRPS34,ZDHHC4,WDR5B,CDC20,SNRPG,ADTRP,XRCC5,TIMP4,ACCS,TYROBP,WDR11,NHEJ1,SLC35B3,FHOD3,AIPL1,PEX13,TBC1D25,TNFAIP8L1,NBN,VMAC,IL2,SEC13,LRRC40,DPH3,ELK3,CRISP1,CD81,RHOBTB3,HGS,POLDIP3,FSTL1,UBE2E2,TRAPPC13,TAS2R13,DBR1,PRKCE,ZNF451,WDSUB1,GNRH1,PRKRA,TSPAN17,COX6B2,RNF133,TMEM170A,CGGBP1,PHF13,RPL26L1,PARP2,NF2,ABHD12,BANF1,CARTPT,SESTD1,KLHL1,FOXA3,NUDT9,CYGB,IL17F,PPAT,TNF,GGH,CCR4,CHRAC1,KLF3,LZTFL1,SNRPB2,SUMO2,TFB1M,CDH11,PSMC3,JAKMIP2,SNRNP40,FAM83B,IVNS1ABP,PIK3CA,NDUFS2,PAIP2,TMEM185A,ADORA3,APEX2,SF3B1,TAB1,AKR1B1,MAD2L1BP,TMEM47,LY96,AP1S2,ANKMY2,CNN3,CPT1B,ZBTB39,RBM27,RPIA,VTA1,COX6C,PICALM,XAF1,PIK3AP1,FEM1C,COCH,PSD2,PEBP4,BAX,GH1,ATP1A3,NUDT2,NPM3,TMEM38B,TSPAN15,GSTM4,CRTC2,ASPA,BCL9,LYPD6,ELMO2,TRPC1,HS2ST1,GTPBP8,CBX3,DR1,MIS12,TMEM89,PRNP,CAND1,HSD17B10,GABRA1,ZNF263,TPPP3,SGTA,USP6NL,MTDH,CA2,SNX10,DLST,GTF2F1,GSTCD,TMED9,SYNPR,BCL6,SSX2IP,MGMT,SP1,CCSER2,MTCH2,ITM2B,MDC1,TRAPPC6A,IMPA2,ECHDC1,FUNDC1,AP1M1,UBA52,TMEM196,TADA3,TRAM1,CCDC106,ETNK2,CLDND1,SPRY1,ROCK2,KCND3,FUBP3,VPS72,KRIT1,TBCCD1,TRAF6,RPL18,GIN1,TKTL1,SUCLG2,PDE7A,DUSP3,ZNF581,VPS18,GHRL,CIAO1,ATP8A1,KIF3C,RUNX1,SLC12A2,GJC1,NAA16,TAPT1,TYMS,ZFAND6,SCML1,DIRAS2,ACER3,MREG,EIF5B,PFKFB2,ARHGAP12,SRFBP1,FAM161A,PDE12,ANKRD6,YTHDF2,PSEN1,MAGEC2,OR13A1,LCORL,EDA2R,LMO2,FKBP1B,RBP2,TLCD1,AQP11,SSBP4,RASSF8,CLEC6A,KCTD17,DMPK,ELFN1,MBD3,CDC23,MPG,SYNGR3,BRAP,TANK,KCTD3,PIH1D1,RDH11,NKAP,LBX1,LRRC8A,GNGT2,CNPY1,SSPN,HAUS2,OR5M9,ELFN2,RP9,GALC,CMA1,DLGAP4,GRIK1,RRAGB,SNRPE,GALNT2,IL18BP,RASL12,ANXA4,TTC9C,GMPS,PELO,THUMPD1,GORASP2,RXRG,SNAP25,CCR7,IGF1,FEM1B,MRPL9,UBE2G2,MECR,SGIP1,FXN,SUPT3H,UPRT,CPNE2,CYTH4,IFT172,RAMP3,KLRC2,TOX4,CENPL,TRIM26,NUCKS1,IER3,RPE,SULT1B1,KLHL25,TMEM165,OR8B4,IRF7,PTP4A2,FAM3C,MFAP3L,SLU7,VEZT,WSB1,LYZ,TOPORS,SLC25A5,PRR13,FAM136A,SLC35E4,FAM151B,ZNF518B,MACROD1,ADCK1,CYBRD1,NRM,THAP8,WDR45,CRYBA1,MPV17L2,HSPB6,GNA11,SERTAD2,HSPA5,FHL3,TICAM2,FAM20B,PQBP1,GPRASP2,PPWD1,TRIM44,LRP10,PAIP2B,NR1I3,ITGB8,BTG2,VAV2,CCDC3,GNB3,HINFP,NUFIP2,CMC1,TMEM229B,BTG3,DPEP3,TMEM183A,GADD45A,IGFBP3,GRPR,RUSC2,CD9,OR1M1,ZNF622,ATG9A,S100A11,VPS54,SLC25A27,RBMS2,TGFB2,BOLL,MX1,GLOD4,PIGA,THOC3,CAP2,TMEM81,SAP18,EXOC3,DDR1,SPG21,TIA1,SLC22A6,RNASEH2C,HSPD1,EIF1AX,LRRC28,TCEA2,PARD6A,NPC2,TMEM115,NUPR1,PIAS1,PNPLA4,DCTPP1,TMEM100,OR4A47,PRCP,EID2B,CPXM1,UNC79,THAP1,CD34,FBXL4,SRPK2,TAB2,RGP1,CCDC90B,PIWIL1,TRAF3IP3,TMEM107,RPA2,RNASE9,GADD45G,YPEL4,PRSS8,LDB2,CRY1,CD40,AIP,SLC6A2,TNFSF15,PMPCA,TLR8,ARFGEF1,MED22,NOG,ZNF428,PDE2A,CDIPT,TNFSF8,PYCR2,FKBPL,RGN,CTTNBP2,RAB6A,PLAC1,PSMD7,SIN3A,CDK7,POLR1D,GPR160,DTWD2,PSMD3,NCAPG2,SRI,CNPY3,APLNR,CYP4V2,POLE3,KRTAP8-1,GP9,OR51E2,FAM133B,RNF10,ZDHHC16,OR4D5,TEX261,MSH6,RAP2A,PPP1R11,MDFI,ST3GAL2,TAS2R7,CD209,FBXW4,P2RY4,IP6K1,IL2RB,PTGFR,GLCE,GK5,SSNA1,SPINK9,SLC25A24,SUPT5H,PDCL,RPL10,TRIP4,STAR,SCG5,PHOSPHO2,MAT2A,NMRAL1,RFX5,TRAPPC2L,TMEM198,OR6C4,CDKN1B,CMBL,COX7B2,SCHIP1,HMGN4,MEA1,TAF9,AHSA1,PLEKHF1,ZBTB6,SLC15A1,KCTD16,GPR78,HNRNPAB,ZNF655,TRIM62,TEX19,CD200,TMEM168,USE1,ST8SIA4,TMEM220,NCK1,STRADB,LRP3,SIAH1,NAA30,C9orf72,CDR2,PTGER2,NETO1,DDX39B,CGRRF1,LSM4,HSD17B8,IRF9,SEMA3C,DOK6,PSMB4,HERC3,KCTD20,SERPINA3,RASSF4,CLK1,SKAP2,RSL24D1,TRAF1,BRS3,ZMAT3,MGST3,TSPAN3,BAD,OLA1,HAS3,PRPS1,AKR1E2,CRHR1,NOC4L,UQCRC1,LRRN4CL,GDAP1L1,SSBP2,PDCD10,WTAP,RPL31,ZSWIM7,TBCEL,UNC45A,FKBP2,PRSS35,ISG20,TMEM87A,NUDT1,RALB,GMNN,CYP26A1,SNRPA1,CEP70,ABHD2,ANKRD46,ARL6IP5,CTDSPL2,PSMG2,DTL,NDFIP1,KDM1A,CCDC22,WNT2,GMDS,TRAPPC3,CSRNP3,NRGN,LDB1,MFSD3,BIRC5,CAMKV,ARL5B,F2,ESYT1,ANKH,VPS26B,YKT6,AANAT,EDC3,SAP30BP,HAPLN2,RHOU,DLG3,B3GALT4,CEBPE,RPL22,TMEM176B,RANBP1,CTLA4,RBM5,ATF3,MAP1LC3B,PDLIM3,PRSS37,DEFB1,IFRD1,ACSS2,EMX2,SEC61G,CENPM,SSH3,HOXB8,GFM1,ADIPOR1,GAL3ST4,PRM1,MET,FZD6,RETSAT,POPDC3,SLC7A11,SNX11,SERPINB9,UBE2V1,TIMMDC1,IMP4,HELT,PDE6A,STARD7,EGR1,DIO2,WBP11,ZNF436,ZNF343,SYPL1,CHTOP,SETD3,GPR75,ACP2,FOSL2,GNPAT,ACTL6A,PIK3CG,RPSA,NPBWR1,HYAL2,UBE2S,ERLIN2,ARHGAP15,RHOH,CORO1C,RACGAP1,RBM3,CCDC126,RRP7A,STT3A,MAGEA4,HPCAL1,LIPT2,MRGPRX1,SEMA7A,NAP1L5,CYB5B,APOC2,ZCRB1,MED4,BCKDK,OR9I1,TRMT5,TACR1,ARHGAP19,CEP57L1,OSBPL8,CA14,DIS3L,CEACAM5,NAP1L3,MTA3,DRD3,EMILIN3,CHRM5,NACC2,TBC1D1,GPR34,RPF2,XBP1,TIMM13,GABBR1,ERCC3,THG1L,PDLIM4,SMARCB1,HTR2A,ACTR1B,STAP1,FMO1,STARD5,ABCC2,SUGP1,ALG5,DCAF16,CLRN2,SRD5A3,DNM2,OR4K13,TSPYL4,C1QL2,PLCXD3,REG1A,MMP20,GTF3C4,APEX1,PRSS1,PSMC5,GAB1,ITPRIPL2,JMJD8,AKT2,KCNG3,CHST10,SOX9,PNPO,OR2D3,COTL1,GPM6A,HS3ST3A1,TICAM1,TLR5,HIGD1C,LCN1,RFC4,AQP3,RIMKLB,PSMG4,PRELID1,APMAP,ETFA,CD59,ECD,GLO1,RAB1A,PDCD1LG2,NEU1,AMELX,VSTM4,PIGK,PELI1,CNOT8,ZDHHC17,MAP1B,VSTM2L,FBXO31,KLF12,MLN,IAH1,WDR12,TMEM231,TCTA,SOD2,ADD2,SCN2B,ANKRD10,TEF,VWF,ATP6V1D,CDKN2D,ESD,GPR37,TMEM39A,ART5,PSMB10,CHMP1B,CDK17,IFI16,PTPRZ1,SART3,MYLIP,SUPT4H1,VPS39,INA,ATG3,CFTR,CLP1,CLPX,OR5AN1,TULP3,HS3ST1,BMPR1B,OR4M1,SPDYE4,ADH1B,RANBP10,SRM,MED27,BARX2,PSMD1,MPP1,CRYZ,FOXC2,RAB32,PITPNA,CRYBA4,BLVRA,FAM193B,APOBEC3B,MLH3,PCBP4,RGL1,SUV39H1,SEC14L5,RPL4,HBP1,SPAG11B,CKS1B,DYNLRB2,RBM41,COPE,SLC25A3,RWDD1,PABPC5,HCFC2,DCTN3,IRF2BPL,PRKCB,CHCHD2,SKP1,PCYT1B,CSF2,PRELP,KRT8,GJB1,GCHFR,HNRNPH3,LCP1,AGGF1,TPST1,ZNF200,IZUMO2,DIRAS3,TP53TG5,ATG16L1,SIGLEC5,HDAC11,TTLL10,JUNB,ALCAM,SNRPD1,CCL24,LIPA,RNF182,RELL1,TIMM17A,SMAD9,PTPN5,LCN15,MB21D2,PGAP3,TCEA1,BCAS4,HM13,SLC39A10,MCCD1,VCPIP1,WBP1L,OAZ3,SLITRK1,DDIT3,SRP72,FIS1,EDEM2,RPL28,CACNB2,CYP4F22,STK38L,MVD,PIGC,ARFGAP1,SHC3,CDC26,PREP,ADRB3,FMOD,TBC1D16,CA12,SLC7A1,SPATA4,CMTM7,LEMD3,CSRP1,IRF4,CCND3,RAB11B,ARL6,STX5,OPRL1,LYPLAL1,HSDL2,PLP2,ABCF1,DUS4L,RNF139,SMG5,NUP62,THOC6,PYCR1,TNPO2,HINT1,RPAP3,RXFP2,RAB9A,CCL11,MARCKSL1,IFNAR1,SDR16C5,SLA2,SLC6A7,MAGEB1,DICER1,SLITRK5,RNASE4,DDIT4L,SAP30,FGF16,POU5F1,HBM,MSN,ZNF362,RPL19,IL21,MID1IP1,SPCS1,TDP1,GLIPR2,PLEKHF2,SNRNP70,SERINC1,PNRC1,SLC41A1,LAMTOR2,MXD1,MFAP1,MED29,UBE2I,UCP2,TMEM106B,ARL11,FHIT,MAP3K3,KRTAP4-1,TECR,MRPL16,RNF7,EZH1,ARGLU1,SPHK2,FAM20C,RCHY1,MRPL12,FGR,B3GALT2,PPT1,ARF6,ZDHHC24,DCTN4,SEC22A,MAP2K3,DOK5,FIG4,LSM12,CXXC1,RPL7A,SH3BP4,LEP,SMARCE1,PITHD1,ZC4H2,TADA1,CETN2,ZC3H14,CBFB,EFNA5,ASPM,IFNA13,CACNG3,RIT2,LRFN3,S100B,TNIK,OR5K1,PDE6D,PDZK1IP1,OR4B1,UBE3A,NPB,CTSA,DPAGT1,ZCCHC7,PHTF2,PPIL3,GPR83,LPCAT3,ZHX1,KCNIP2,SERTAD1,ERRFI1,FA2H,HNMT,CKB,TUBA1B,THAP6,HMGB1,PHF7,MRPS26,GNG11,ZMYM6,EIF2B2,ARF1,BTBD10,PDCD5,PRDX3,EMILIN1,LRRC14,ZBTB26,BGLAP,COX7B,NOL12,RHOG,FAM83A,ASB11,RGS1,SDHC,SEC61A1,TTR,METTL18,RSBN1L,GAD2,CDH7,ASCC1,SVIP,SMUG1,RPS28,UBXN2B,DUSP18,TPD52L1,ZNF770,ZNF345,KIAA1958,FBLN5,FOXD3,MAEA,CXCL10,MRPS25,RBCK1,NFE2L1,AKR1A1,NOP58,SPATS2L,MRGPRX4,FABP5,CTSD,COA4,PGAP2,NLGN2,DEK,SLC5A6,PRKD3,CYP4F8,SPEF1,NUP107,OR52M1,SCAMP2,CD164,BPGM,CDKN3,PPIB,ARMC8,ENTPD4,SLC35A2,PTDSS1,ID1,POU1F1,CYC1,CCDC42,FCAR,NPTN,CRYBA2,DEGS1,ING5,INPPL1,MIA2,BACH1,KIF2A,KLF10,MRPL47,TMEM33,S100PBP,MPHOSPH10,AP3S2,SCG2,ARHGAP21,RHCG,SPINK13,FAF2,BMPR1A,OTUD6B,SETD4,LCN6,FBXO9,COX7A1,WFDC13,TMED3,OR2W1,RPGRIP1L,CCND1,CPT2,CHST9,ANP32B,AP1G2,NDNF,DCAF8L2,CETN3,URM1,CTSK,CACYBP,RAB3C,MTAP,PWP2,TGFB1I1,DUSP1,BATF,TOLLIP,STX8,S100A10,FAM200A,NFYA,CLEC12B,OAZ2,SFTPD,SOCS2,INTS12,CYP2D6,CTNNB1,RAB8B,CWF19L1,CDK6,DCAF5,ESR2,FAM13B,SNRPD2,ADCY3,USP39,CERK,SLPI,USP38,ZNF174,PROX1,PRKX,FGF13,ZMAT5,RTP4,LSM6,SYNGR1,NAB1,ENPEP,VPS4A,EIF4EBP2,OR2A2,SV2B,HPCA,ZNF805,SOST,TCP11L1,NDUFAF2,GPR37L1,SNTA1,SNAPC1,GFOD1,SIVA1,EMC4,SPRED1,NONO,POLL,TSSC4,ALDH1L1,MAK16,IQSEC1,NOL4,FYTTD1,SIRT7,ETV6,RRAGA,TAPBPL,TNFAIP3,ABHD16B,RAP2B,DUOXA2,MTMR12,MMACHC,TRAF7,IL34,DFFA,LPXN,RASGRP2,ST13,CD2,POLR2I,TIGD7,FBXO30,RABAC1,WWP2,RAP1A,UCKL1,ACAA2,HBB,FGF17,CXCR1,NEDD8,PTCRA,TRMT6,NDUFA5,CCL21,KCND2,OXNAD1,BRI3,OCEL1,ADAT1,HEXA,TMED1,RBM23,PAOX,BRMS1,CD3G,KIF1C,GAS8,CHRNA7,CDKL2,NPVF,AKR1C2,LMBR1L,IGFBP4,TAC1,OPA3,TBCE,SPATA2L,IPP,NQO1,SOX21,RAB4A,TRA2B,DHX16,LEAP2,HADHA,LHFPL1,B4GALT6,HSPB1,KCNA2,GXYLT1,OR6M1,PGBD2,SIPA1L1,STAMBPL1,CLDN14,ZKSCAN1,HSPE1,SERPINH1,MSX2,NLE1,KRR1,PELI3,CDC37L1,SNAI3,FRA10AC1,PDIA3,XPOT,CXCL1,ISYNA1,APH1A,NDUFB8,EIF1AD,NAA11,LEPR,STX17,WNT7A,WDR37,EIF4EBP3,OR51S1,ZSCAN1,FURIN,SLC39A9,DHX9,PSMD6,IL23A,GNMT,CCL25,TXNIP,CREBL2,AQP4,GLE1,MOB3C,LASP1,PHKG1,SPOCK1,NEK7,UTS2R,GTF2A1,WBP2,FUT8,GALE,SH3GLB2,EIF2B5,CIRBP,ANKIB1,ENDOD1,OSR2,CXXC5,RNF187,GPR162,APOBEC3C,ZNF513,SLC7A4,ZMYND11,XPO1,EXOC2,GJA10,SLC25A32,EFHC1,EEF2,THRAP3,CREB3,RNF103,TF,INTS10,XPO5,ABCC5,THOC1,NUDT19,RANGRF,RC3H2,FATE1,ATP2C1,DNAL4,PCDHA5,SLC20A2,UBXN10,PFDN6,LDHA,NUBP2,PRCC,GSK3A,TRAPPC1,NIPA2,RABL2B,PAEP,CLDN11,FAM199X,NPY2R,LRP12,RNASET2,SPTAN1,SLC35E3,FRMD8,RFX4,ZDHHC14,ADRB1,PKNOX1,PCDHB8,RBM17,HEY2,ARMCX2,ACTA2,TRIM21,SIX5,PPARG,ARFIP1,GALNT12,SPR,HNRNPC,SETD5,PTPN1,ZBTB38,HECW1,TRIM37,NFIL3,PGS1,RBBP7,SLC25A21,RMND5B,PRPF4,ARMCX5,RAB18,IDH2,FKBP14,CD58,AGER,IMPACT,SLC39A7,SORD,SBK2,MCOLN1,PSMB5,CCT5,ENPP4,SMCP,AGK,ANAPC2,FBXO32,SHC1,OR4K1,PYGM,FGFR1,CAMK2N1,HCRT,PPP3CA,CRYGB,KCNJ11,CD200R1,CCDC127,PEX3,RCVRN,FAM89B,CAMK2G,BUD31,TMX4,SRP54,TACR3,CIB3,PRMT2,CACNB4,RPL15,TUBG1,PGA4,GHITM,TTC4,SCFD1,CCDC47,ROPN1B,VRK1,PGK1,HEBP1,SLC7A9,PACSIN3,ALKBH4,SNAP91,MYH2,DNAJC5,TMIGD1,LHX2,UBAP1,ZYX,CDC73,CYP27A1,S100A6,DYNC1I2,BTF3,MMP9,SUPT7L,JOSD1,P4HA2,OR4D9,AFTPH,LSM3,RS1,KIT,KPNA1,PIWIL4,CSNK2A1,GRSF1,RARRES2,ATF4,CTNNBIP1,GNG7,GSTO2,KBTBD2,DHRS3,TNFAIP8L2,DEFB116,NDST1,DNAL1,KTI12,SMAP2,RAB3B,CDCA3,AZIN1,PSME2,ABCB1,INO80C,HBE1,AZGP1,FGF1,JAK1,LBH,GTF2E2,MLF1,TBC1D10C,MAGOH,NKX3-2,ZNF24,TMEM215,FBXO42,TSEN54,SERPINB10,ATP6V1G1,WDR77,MTPN,FZD4,MEST,AAMP,TMEM213,MX2,GPBP1L1,SYN3,ZCCHC10,MFSD6L,LYG2,IL15RA,OSM,SLC38A9,MIOS,FAM78A,PPP1R2,RMND1,DHRS4,HSBP1,SLC35A1,IMMP2L,MEF2A,RAG1,ENY2,SLC30A5,KLK3,SNAPIN,ZNF304,MRPL50,EIF4H,ITK,NCR3,FAM8A1,SWAP70,LRRC69,HSD11B1,CYP39A1,MYL12A,GNRH2,CHDH,CYP11B1,PYDC2,GRM2,CTNNBL1,GALNT4,IDH3B,SENP5,GPAA1,ADGB,JAKMIP1,TLR3,CCR6,TAAR1,SLAMF9,ZMYND19,XAGE5,APOBEC3A,ZNF397,ID4,SEC14L1,ZNF319,CDK5R1,NCKAP1,NRP1,GLUL,LMO4,KIAA0232,ATPAF2,CLU,CASK,OR4D11,GAL3ST1,LTBR,GRPEL1,ELMO1,TCP11L2,PRPSAP1,GABARAP,FGFR1OP2,ARMCX1,UBE2A,CCT2,CHRM4,UBE2D3,ATP6V0E1,NHP2,NAIF1,TRIM23,OR8B8,IRF1,STRBP,ING1,P2RY1,EFCAB7,GPR89A,ZMPSTE24,EXOSC1,E2F6,GFM2,GDI2,MRPL23,PLA2G5,KLK9,DOK4,ARHGAP1,RNF141,KLHDC8B,TRIM32,CD99L2,PRIM2,SNRNP27,SDR42E1,UBR7,PDIA6,ZNF671,SLC25A31,SLC17A5,RPS14,LIG3,LYPLA1,MEAF6,UGCG,ZNF207,EDF1,ATP6V0B,TMEM219,C1QC,TRIM3,TMUB1,POLR3H,TLR9,L1CAM,FIBIN,SNX20,WDR38,DLX1,AKT1,APEH,FGD2,COMTD1,FNDC8,SF3B4,DKK3,IL20RB,CRABP2,DPP10,PRRC2A,CDO1,RAB11A,PPIL4,CCNI,ASMT,PFDN5,EXOC8,UST,TOM1L2,LYAR,B9D1,NUDT3,CNP,RND3,PSMA3,CCDC69,GALNT1,AK2,SOCS5,TMEM156,GSTO1,EHBP1,MGP,MDM2,MRPL13,ABHD6,CLDN1,METTL2A,TFCP2,CRYBB2,NDUFAF4,AKAP14,FAM162A,CTDSP1,CCNB1,ADIPOQ,ANKRA2,ERH,ALKBH5,UHMK1,LCP2,CRTAP,METTL14,EDEM1,GNG2,JPH4,AMIGO1,TOR2A,PTS,MBL2,GTF2H2,MAP3K11,SLC35D1,SMU1,RMI2,COL1A2,SAT1,CSGALNACT1,R3HCC1,GIT2,OAS1,NKIRAS1,CXCL3,GTF2B,RUVBL1,SDF2L1,RAB3D,LAMB2,SLC13A5,CLDN4,KDM4B,TMEM184B,ZNF287,TMEM114,ACAT1,TRIM54,RPLP2,CDC42SE2,ACBD7,FAM98A,GPX6,POPDC2,GREM2,TGIF2,RDH10,LDOC1,PDCD4,GPAM,PRPF19,CREBBP,OR4Q3,HTR1F,DNAJC22,EIF2B3,TMX3,HTR5A,TCF23,PAPSS2,GBE1,CHGA,TEX30,GPR65,BCL7B,TOM1,GCNT3,OPRK1,NKX3-1,F9,PGPEP1,ZNF740,NDUFS8,CYP2C18,MYO6,APOO,BCS1L,SNX17,GPR137,NRSN2,SRRM5,TMEM144,TOP1,ZBTB5,CCR2,AIF1L,ZC3H7A,DSTYK,ATAT1,ARMC7,CIDEB,IPO8,ISG20L2,GPHN,POLE4,HSP90AB1,MRPS23,FUNDC2,CSRNP1,SYP,ATG4A,ZNF862,SFRP4,RGS7BP,CDKN2AIP,FCN2,RER1,HOXD12,ADIG,RTKN,NTN4,FUT9,PHYH,IL10,UBE2V2,RPLP0,GOLGA7B,TSPO2,OLFML3,PREPL,SH3GLB1,RNF113A,EFNB1,IFNA10,DEFB114,TFE3,COMMD8,ITGA6,CSNK1A1,PELP1,DDX39A,RAB40AL,AKAP12,IGBP1,SSU72,SNCG,COX4I2,CDKN2C,CALHM3,LHFPL4,EIF4E,TRIM5,TMSB4X,BZW2,TSPAN5,OR10G9,RINT1,KHDC1,NAT2,SPECC1L,B3GALNT1,CREB3L4,EIF3K,CD274,FABP7,ZBTB17,BCAP29,ABHD14B,EED,MTRF1,ZNF592,DTYMK,ACSL4,TRIM24,MRFAP1L1,TGFB3,CIB2,YAF2,ELP3,EWSR1,B9D2,TMEM204,PROS1,GPX3,CHMP2A,OSTM1,EMP3,MSMP,HSPA8,VMP1,SLC19A2,CBR4,ADO,CALHM2,GMPPB,BECN1,LMNB1,FAM219B,CCDC25,TES,SERINC3,SLC41A3,KLK6,FKTN,DNAJC3,RNASEH1,TMED7,STAU1,STOML3,TSN,DPY30,NR1I2,CNNM4,CDK4,NPR2,RBM7,TRAF2,KCNK13,PCDHB1,ABHD4,BRCA1,NOS1AP,BCL10,KCNMA1,MBD5,PDHA1,ADPRH,DUSP19,NME1,STMN2,RGS2,PARP11,SLC32A1,FAM163B,POR,ST3GAL5,IFRD2,CEP97,ZNF501,NDUFB4,RAC2,LCA5,STK24,PYROXD2,MRPS21,TAS2R40,LRP6,STXBP1,PAX9,KLC2,PCMTD2,STOX2,ERV3-1,CD36,IRF3,MTHFD2L,UQCRH,DPEP1,PRKAB1,IL18,DERL1,ST3GAL1,CSNK1A1L,SOX2,PNPLA8,MYEF2,TAF5L,MOV10,NGB,GLT8D1,GDE1,TCEAL7,TMEM14A,GPX5,PCGF3,CPSF2,CDH8,OR14J1,FLYWCH2,GRIA2,LRRC24,MRGPRX2,DDX4,CAB39,KLK5,LIX1,SLC43A2,ZCCHC9,TMEM91,TEX12,B3GNT2,TOP3B,SNIP1,SLC4A8,LY6G5C,UBE2D1,ACTL6B,FAM168A,RAB1B,INHA,RPAP2,OR5L1,RGS5,ZBTB45,ABHD13,HRH3,AMY2B,RBMX2,NDE1,CD2BP2,TDRD7,HMBS,SELENOV,LDHAL6B,CCDC65,CDKN1A,GK2,RBFOX2,FOXN2,STX18,ORAI3,ELSPBP1,SLITRK2,CLIC2,SDHAF2,PPFIA3,OTUD7B,SOS2,PIWIL2,AKIP1,SLC23A2,GYS1,PGM2L1,ROGDI,FOLR1,SLC6A11,RAB37,C1QL1,PSRC1,IFI35,FBXO25,CSTF2T,CAV2,STK38,TIMM10,WEE2,PCDH19,RAB5C,PNP,SMN1,EIF4B,PPP2R1A,SMAD3,SLC25A4,PTHLH,MRTO4,DERL2,TXNL1,TIMP1,PLEKHJ1,MLF2,ELMOD1,LYNX1,RPL23A,IL6ST,TMEM59,FGFBP2,ARCN1,EZH2,INPP4A,KCNIP3,AMT,RAB9B,PHYHIP,DYRK1B,FN3KRP,WIF1,ACADSB,SNX24,ISG15,OR10G7,STAT6,SNRPA,CMPK1,BEND5,CCNF,VAMP2,TRAPPC6B,GPIHBP1,WDR44,CTNNA1,RAB2A,VPS33A,SACM1L,CD226,CRBN,ZFP1,PDYN,B4GALT3,ATP6V1C1,GGCT,RCBTB1,HNRNPA2B1,TAPBP,MAPK1IP1L,PLA2G15,STX6,FANCG,OR2A25,CCL8,NAA60,CAPZA2,SLC35E1,RB1CC1,TPPP,RFTN2,PPID,YPEL5,ABRACL,DYRK2,FOS,EGLN3,CLDN22,OS9,RPL26,POMP,OAT,MRPS28,RIOK2,PRKAG1,PAFAH1B3,HNRNPK,NFKB1,SCD5,MAFG,ACAP2,LHFPL2,SPTBN1,TNRC6C,RNASEL,CHI3L1,UTP23,GIMAP2,GNPNAT1,EIF3J,TOMM40L,FERMT2,DNAJC8,PPDPF,TNFSF18,FAM107A,RNF167,CRYGD,RAB33A,ZNF687,OGG1,CCR3,SUMO3,OPHN1,PTGER1,RAB23,CMAS,SFT2D2,WWP1,CBLN4,RHOJ,CD47,HIRA,S100A8,IFNG,JUN,TMEM50B,ACTR2,TAS2R5,TMEM203,PTRH2,FOXS1,CRYBB3,OR4F6,APLN,TMEM164,ACP6,SYNJ2BP,KCNK10,SLCO1A2,ZNF609,TMCC2,SELENOS,MANSC1,WDR3,GJB2,KRT7,PLEKHA8,TMEM106C,SRP14,NUS1,GCA,ZNF576,RABL3,UPF3B,ISCA2,EHD1,MPV17,CHST1,FCHO2,TRAM2,PPP1CB,PAPOLB,PLAGL1,SESN2,TRAM1L1,RFXANK,KLHL15,RPL6,SPRR1B,TUSC3,CXCL14,ADAMTS1,CLDN8,BNIP3L,SLC7A14,DDX42,PXMP2,ATP1A2,MT2A,PPP1R16A,GMPPA,CYB561D2,BRD9,LCN9,HAND2,PGR,POLR3B,NPY5R,CXCR4,HSPA14,DLG4,GTF2F2,PAFAH1B2,OR2H2,CCL17,KIAA1191,KCNH1,KIAA0408,RNF122,SERPINA5,BICD2,TMEM177,FMO2,GLIPR1,SQSTM1,RPP25,RBM12,RAN,NEGR1,FDFT1,SIT1,CCDC160,RPA3,MOXD1,EPHX1,ABHD5,CXCL13,CKS2,RORB,TXNDC12,RWDD3,SNRNP48,FRRS1,ATG4C,GFPT1,SDHB,PTEN,RLIM,INO80E,DEPDC1B,CRLF3,UCN,MGAT5B,PTAR1,THAP7,UAP1,CLDN3,ADAM21,DNAJB9,ARG2,RNF144B,SIAE,ISX,GAMT,RTN4,GNAZ,OR10A4,ELMOD2,USP15,LPAR2,FKRP,CNRIP1,APOBEC3G,TWIST2,NTRK2,PABPC1,GNG12,SEC22C,METAP2,MME,ZFAND2A,NRN1,MAPRE1,GNG10,MUL1,SMG9,DNTTIP1,HR,LRRC3,ARPC3,DKC1,FBXO44,PCYOX1L,CREG2,PLD3,AGPAT5,OPRM1,CDAN1,SPRED2,DDX23,PCNA,PDE1B,UBE2K,PIK3R2,NDUFS6,CTSC,NXT2,HNRNPA0,CHST2,IKZF5,FZD3,CD247,RHOBTB1,NEUROD2,BABAM1,METTL15,PGRMC1,PTK7,COX20,DHX38,GPR171,COX8A,LGALS8,USP8,TMEM147,HTRA2,NDUFAB1,SNAP29,JAGN1,TYW5,NUDT12,CBLN2,RPL27A,BCL7C,IL1A,OR4D6,THBD,PPFIA2,CNDP2,FBXW11,CINP,HENMT1,RPL7L1,CSTF3,CSGALNACT2,ST6GAL1,REEP3,BFAR,TOMM22,TMEM179B,TOR3A,CBLL1,UBA3,SRSF7,EPCAM,PCDH17,SAV1,STAT2,TAGLN3,IL22,PRR3,SFXN2,SNX22,FASTKD5,CST11,NCDN,CYP21A2,GNAO1,NDUFB6,MRPL34,TMEM117,TMEM170B,IRAK4,IMP3,UBL3,TMEM30A,AFAP1L2,KCNJ3,B3GALT1,COMMD6,GNPDA1,SLC6A6,SLC30A7,TCF19,CCDC134,PDHB,DDX46,MAT2B,ZNF664,MLC1,OCRL,XCL1,BBS5,RPS6KA4,GANAB,TSPAN18,FBXL14,RHEB,DHX15,OVOL1,NPPC,PSMD4,RPS7,GRAP2,RAB27A,GPX1,TRIM15,RELL2,SCLT1,MRPL11,DAAM1,LRRTM3,ANKRD34B,LSM10,HSPA13,NPSR1,LMAN1,PPP2R5E,SH2D1A,UBB,SLC11A2,LARP4B,STX11,OR2Y1,SERPINA1,PMP22,SLC38A7,PGGT1B,KCNC1,OXTR,SUFU,MTA2,CCDC86,MRGPRX3,FBXL19,LAPTM4A,CHIC2,CHCHD4,TMEM101,HINT2,NUF2,OR13C8,SLC16A1,PCDHB13,RPS27A,DSTN,DAPK3,ELOVL7,RAPGEF5,DBT,TPD52,METTL21A,PSORS1C2,POP5,CHAC2,G3BP1,MFSD5,FGFBP1,MRPL18,PPP1R1B,RND2,BMPR2,COMMD3,SCG3,OLFM3,RASD1,CCS,NLRP3,ILDR1,SCGB1D1,CFC1,NDUFAF3,CHPF2,IER2,CNTN2,ASNSD1,NR2F6,DKK1,HERC4,PSMB1,CRIP1,ZMYM3,OXSR1,ILF2,ORC5,BAG3,ZNF365,KDELR1,TOM1L1,RBM22,RRM1,KRAS,RPS16,ADD1,JKAMP,CLEC2B,SEPHS2,CBR3,ODAM,CLPB,VDAC1,FEN1,KLF1,ASB7,PRKACB,GLRX2,LANCL2,APOBEC3H,GSTM5,ERAS,PLEKHO1,MYBL2,ZNF326,CRHBP,CNOT2,OTOS,CHKB,CCNY,ELF5,CLDN12,GPR176,PKP4,SCML2,DNAJC19,VGLL4,FCGR1A,IFIH1,NUDT7,FCGR2B,BIRC2,MTM1,EPS8,UPK1A,HOXC4,CHCHD6,SIAH2,POLR1B,CER1,CDCA7L,SS18,CD1C,RAB19,UMPS,KLHL22,MAVS,UBP1,IGF1R,FAM219A,SLCO2B1,CX3CR1,PDAP1,SOX14,CHMP4C,MCM4,SCNM1,DCTD,FAM177A1,STARD4,THOC2,ORC6,FLOT1,NR2E1,DROSHA,CYP2C8,METTL22,ASZ1,CAPN1,USP3,TGFBR2,CEBPG,CDNF,TNFRSF1B,HP,VAMP7,CTTN,STOM,RPL23,CLLU1,ANP32A,SPIN3,FBXO7,RABGGTB,SLC2A3,SEMA4C,PPAN,IL2RA,SF3B5,RCL1,KLHL24,FKBP8,GABPA,PPP2CB,CHST13,ZNRF1,CLEC18A,SPC24,SMAD1,AQP2,TIMP3,PPP3R2,PRSS12,PRMT6,PMM2,TTL,TMEM70,VAMP8,MPDU1,ADAMTS10,MRPL20,EP300,AKAP8L,RNF8,PEA15,TMEM167B,HSD17B6,MAP2K1,PLCB2,APOBEC3F,FPGT,LRRC3B,EIF4A2,OTX2,MAGEH1,PRDM4,FEZ1,STAT5A,COPS5,EFNA3,TPM3,SNRPB,MORC2,SSR2,ELOVL1,SOSTDC1,RIT1,OR10P1,CHRNB2,GPX7,PTPN4,LAMP2,TMEM237,RNASE1,TMEM45A,FAM43A,NLRP9,GSTP1,LLPH,CCL2,OR8B12,PPM1K,AR,IFI6,SNRK,TEX264,AVPR1B,ST7,TRAK2,SERPINB1,GSTA1,SRSF2,UBLCP1,PIP4K2C,STUB1,KLF9,TMEM41A,IL1R2,RBM38,NKIRAS2,FAM181B,ACVR1C,PLS3,CYP1A1,ST8SIA5,TNKS,SLC22A17,STK4,SPON1,PPP2R2C,BST2,DDX50,RPRD1A,GTF2H5,CTXN2,SLC25A10,HINT3,VRTN,ZNF821,DIO1,VGLL2,SLC16A10,SLC35F2,SYNCRIP,TRMT112,CLDN9,PPP1R1A,RPL27,MSTN,RNF148,PRICKLE2,MTF1,PTH2,MRPS9,LTA,ABCG2,UGT1A1,FAM83C,KANSL3,TOR1B,SPSB3,KIAA0513,SEMG2,CCNH,UBASH3B,POLA2,POLB,MNS1,CSH1,BTN2A2,IFNB1,GNPDA2,TMOD2,PTPN11,SOBP,NOTCH2,NAPA,CRAT,TM4SF19,FAF1,VEGFA,TP53INP1,IQCK,AVL9,DECR2,DTWD1,TBC1D13,ATXN10,NCBP2,SOD1,ASTN1,SMPD2,CCR1,REN,HDHD3,SHOC2,DRGX,PSMA1,RPL32,DDRGK1,SLC25A12,HMGCS1,CLCN6,PFDN2,TCEAL1,LTB,USP16,TMED5,HARBI1,LRRC8B,ETF1,TRIM68,ATG7,NFKBIA,NPW,PREB,FAM53B,PRDX1,ACBD6,RNF34,OR10A6,OR4D2,KLF4,COPS7B,DENND2D,ATP6V1A,EGFL7,TMEM59L,HLF,ACP5,SERPINC1,GPM6B,REG1B,FBXO22,RFC3,SLC7A8,PARL,DHRS13,UBE2W,TSNAX,POLR2B,UBIAD1,LRRC61,GTDC1,KBTBD3,PCSK9,PSMA6,PARM1,DNAJC24,AKAP1,CLEC1A,AGA,CD63,LCN8,CPSF4,TMEM174,MORF4L1,NLGN1,TTC23,PCBD1,AGR2,CACNB3,DUSP10,BACE1,SLC38A1,CDC42,SLC48A1,TNFAIP8L3,SLC25A26,SYK,ACO2,VPS16,CLN8,CCM2,ALB,SLC35F1,PSEN2,SNX1,FTH1,IL2RG,PIWIL3,FEM1A,CD40LG,TMEM50A,SMG8,LILRB4,TAS2R39,MYC,CMTM6,VPS26A,EEF1E1,MKLN1,CCL28,PPP1R8,SHISA2,RAB35,MAB21L1,KCTD10,TOP2B,PSMG3,GPR173,OR5V1,TUSC2,SEC23A,GEMIN8,TIRAP,MYL6,RPS9,TCF21,CNKSR3,CASC3,SLC6A3,HEBP2,SP2,VAPB,PNMA1,CALML5,BRIX1,IRGQ,KLHL3,CFL1,TP53I3,DPM2,RNASE6,KDELR2,DDX1,RNF40,RPS26,SFRP1,ELF1,WSCD1,TMX2,HTR1A,METAP1,ZC3H11A,CCL27,G6PC3,RANBP6,SLC25A39,PRR5L,CD14,CYP2R1,SLCO1B3,GOSR2,FGF23,FARSA,UBE2H,EXD2,PTPMT1,KBTBD6,ZNF704,ENO2,OXCT1,PSENEN,SLC2A8,CD86,PNMA5,MANBAL,NAB2,FXYD6,ZBTB25,CD28,TLR10,WDR82,OR4S2,TAF7,APOC4,CYTH2,RNF11,SYNGR2,ROMO1,CRYAB,PPY,DNAJC2,GNB1L,ATP1B3,ZNF473,SELL,KIAA1143,GNL1,CNOT6,CHPF,REEP6,MATR3,LAMP3,TMEM11,TNFAIP1,FAM169A,S1PR4,APBB3,MCMBP,SEMA5A,AGTRAP,CRADD,PPP1R3C,KCNAB1,KLHL9,NPC1L1,TIMM8A,CARHSP1,ACTR1A,LAT2,FITM1,AIFM1,SNX14,POLR2G,COQ10B,RAP1B,RAD21,AKAP17A,DNAJB4,TXNRD2,C2CD2L,CTDSP2,RPL10A,FAH,CAMSAP2,ACVR1B,SDC2,COX4I1,FABP4,MPHOSPH6,TOMM40,GREM1,LRRC4B,GDPD3,ARPP19,ANAPC4,GLRA2,RPL29,NLRP2,MRPL53,HDAC3,PI16,BHLHE40,MAP1S,GRB10,CSNK1E,SKA1,CHMP2B,ELOVL4,PAK6,EIF3D,DNAJC4,RBP5,CCDC92,AKT3,MAN1A2,POLD4,ERVFRD-1,COX16,CUL3,PLSCR3,ARMCX3,CPLX1,OR5A2,RBBP4,COX6A2,POLR3GL,TMPO,UBTD1,MAD2L2,ABCB9,FAS,ATF1,EFHD1,C2CD2,ADIPOR2,LAP3,ALPL,SLC20A1,RCCD1,EXTL2,FOXP1,SLC4A10,HOMER1,PDE8A,PSMB9,TRIM6,PYGB,ENC1,KCNJ8,SAMM50,NT5C2,DOLK,EHD3,ST3GAL4,MRPS18B,DNAJC30,P2RY12,FKBP1A,SRXN1,SPRYD4,KCNS1,TPH2,PHACTR1,SAMHD1,CRYM,API5,LRRTM2,TST,DGCR8,RNF5,RPL9,PRKCA,TFPI,PAAF1,UCHL3,EEF1A1,TRAPPC4,GAS2,WRAP53,MAP3K21,MMD,KLHL26,BET1L,C2CD4C,TTC33,OR2AT4,RPL39,TESK1,DVL2,TMEM108,BRD3,SURF6,FAR2,AHCYL1,ALDH1A3,IZUMO4,ADM2,HMOX2,HNRNPH2,COX11,CLIC4,NPTX1,TMEM45B,BCL2A1,ZNF688,RGMB,SPINT2,HRH2,AP2A1,APTX,ZNF189,EEF1B2,RBM15B,MIF,ACTR3B,TFDP2,ZNF22,C1D,NTNG2,VIP,ETFB,LRRC8D,DGCR6L,WNT10B,SPSB1,RBBP9,FBXO11,C1QTNF1,HSD17B11,PPME1,ZNF177,ZNF652,ZNF267,IDE,TTC8,TFRC,AUH,MND1,GGPS1,TSPAN11,IPCEF1,FOXI3,UTP6,OR1S1,SH2D5,HMGA1,CCT8,TMBIM6,PABPC1L,MTMR2,ICAM1,PLCL1,YWHAH,FAM187B,MRPL49,GABRB3,GFOD2,ADAMTS20,DUSP22,SOD3,KCTD12,RPL12,CD83,DNAJC7,USP30,UFM1,RAD23B,FOXJ3,ORMDL3,CALU,AIF1,HBEGF,CHN2,TMEM60,OR1F1,RPS3,LRRC20,EGR2,HAX1,CA8,OR10Q1,KBTBD13,YIF1A,CTNND1,KPNA2,FAM91A1,LCN12,DDIT4,SMYD3,RAB3A,LUC7L3,HHIP,MAP4,LGALS3,NMBR,NEURL2,SMNDC1,PDP2,CNTFR,KRT222,SNX12,POLR2D,CEP85,ERLEC1,SRPRB,FGF3,DRG1,SDCBP,MED23,USP13,TMEM42,SNX33,NDP,PID1,SRSF4,NECAP2,ATXN1L,SH3BGRL,IL7,ATP6V1E2,ZHX3,ENHO,GINS3,MYL12B,ARPC2,CLEC7A,APPBP2,KCTD11,GPR146,OPTN,RNF128,PTGES,ACADS,TLR7,GAPT,VASH1,PPP2R5A,ADK,G6PD,F11R,FTHL17,RALA,WDR55,EBLN2,NAA15,EXOC5,SYBU,SERPINB6,ZBTB16,ANAPC16,CHORDC1,PAPOLA,DHRS1,HCST,FBXO34,BRMS1L,OR5B3,RHAG,IL12A,SAR1B,CCR5,CAPG,OGDHL,TLR1,RHBDL3,TRMT61A,CAMP,COX5A,SLC1A2,THNSL1,PHF21A,CYP11B2,FBXL7,LBR,CELA3B,OMG,GPD2,RNF181,POP7,STYK1,LYPLA2,SNRPN,TSPO,DCAF4L2,RPRD1B,RGS6,CSTA,TBC1D19,CLSTN3,RASL11A,SLC25A14,PRDX4,NUP35,ZNHIT1,MECP2,TFPT,ELOVL6,ALOX5AP,RPL24,CRYL1,CHST7,SERPIND1,ORAI2,GNPTG,ENO1,OLFM2,EIF1B,MT3,SERTAD3,ZNF250,OR10A7,PSMA4,DNASE1L1,PML,TNFSF12,CALY,RDH12,ZNF790,TAX1BP3,ARF4,SCGB1C1,GABPB1,MAF1,TXN,CYB5D2,RPS12,DAG1,SETD7,PPIF,DUSP6,FTSJ3,TSEN34,SYNDIG1,GSTM3,FCER1G,BET1,CYB561,IRF8,KPNA6,RWDD4,PTRHD1,TOX,HSD17B1,TBC1D17,HEXIM2,TMED4,SLC25A46,KIN,AP2M1,KRTAP3-1,TAX1BP1,PRDX6,INMT,NFKBIL1,CRELD1,PPM1M,TP53,PPM1B,PKIA,TRIM35,TRAFD1,OSGIN2,LIMS2,NECAP1,GPC4,HBA1,GADD45B,SENP8,STX7,MGST2 |
| 3.386e-02 | -3.39 | HCFC2 (host cell factor C2) | protein interactions | 29915 | 91 | 34 | 19454 | 5460 |
TYW3,KANSL3,DPY30,CREB3,GRSF1,IRF9,TRIM23,TADA3,CCT2,CSNK2B,WDR82,ZNF174,UBP1,IRF2,VIRMA,ESR2,KIAA0232,CCT7,TCP1,SIAH1,BUB3,ELF1,NUDCD3,DDX39A,CCT5,THAP2,RAMAC,HSPA8,CCT8,BAP1,CXXC1,RERE,ARF4,CNOT7 |
| 3.386e-02 | -3.39 | IFT57 (intraflagellar transport 57) | protein interactions | 55081 | 91 | 34 | 19454 | 5460 |
ATG16L1,BORCS6,IFT57,SKA2,CDR2,SCLT1,IFT22,LCA5,STX18,IFT52,BLOC1S2,YAF2,SGF29,ZDHHC17,H2BC14,PRPF19,KXD1,IFT25,NDC80,EXOC5,BFAR,FAS,UBXN10,CCDC22,LURAP1,EHBP1,HOMER3,TRAF7,KRT8,IFT172,SPPL3,HOMER1,HSBP1,VIRMA |
| 3.386e-02 | -3.39 | RP2 (RP2 activator of ARL3 GTPase) | protein interactions | 6102 | 91 | 34 | 19454 | 5460 |
TNPO2,GTF2E2,FTH1,MTARC2,TXNRD1,WDR83,CSNK1E,NUPR1,TFCP2,PMAIP1,RAMAC,ABCE1,NMRAL1,STX8,MCRIP2,SNAPC1,TUSC3,GSKIP,OGDHL,CSE1L,HUWE1,KRAS,HDAC6,RAB2A,MYC,SLC35C1,RHOB,GTF2A2,CTU1,HRAS,CBFB,TNPO3,YES1,ARF6 |
| 3.390e-02 | -3.38 | posterior_fossa | COSMIC cancer mutations | posterior_fossa | 77 | 30 | 16828 | 4835 |
CTNNB1,GNA11,PTPN5,ARHGEF6,ATG7,PTPN11,IDH2,SMARCB1,EZH2,HCFC2,MSH6,SMARCD3,GAD2,GNAQ,SF3B1,VMP1,TP53,NF2,CEACAM5,TRAPPC6B,MATR3,MECP2,FGFR1,CLSTN3,ZHX3,TERT,KRAS,IDH1,TBC1D1,DRD1 |
| 3.393e-02 | -3.38 | PARD3 (par-3 family cell polarity regulator) | protein interactions | 56288 | 287 | 95 | 19454 | 5460 |
RASSF8,YWHAB,RHOG,YWHAG,PPFIBP1,YWHAH,CTNNB1,EGLN3,DIRAS3,CEP19,HNRNPL,RHOH,GJA1,WDR6,RAB35,PSME2,RND3,PNMA2,RAF1,IMMP2L,FLOT1,EPHA4,KRAS,MYO1B,PLCB1,HSPD1,NTRK3,LAMTOR1,YWHAZ,RHOB,MYC,PKP4,SFN,ESR2,SIAH1,DYNLL1,PNMA1,ARF1,MYL6,RND2,USP6NL,NOTCH2,STX7,PSENEN,HSPA8,SMAD4,TIAM1,MTMR12,SLC38A2,CAV1,SPPL3,ARF6,RAC2,HRAS,SMAD3,PSMC3,ZDHHC8,ACTR2,SMAD1,CTNND1,SEPTIN7,SNAP23,NTRK2,DLG1,STK11,ATP1A1,SMAD2,EPHA2,UBE2H,DEPDC1B,ARHGAP21,DNAJC5,SH3BP4,VIRMA,F11R,RHOJ,RPS3,CCSER2,GAB1,CCNF,CTNNA1,NECTIN2,PARD6A,RPA2,JUP,FGFR1,SLC12A2,CDC42,SIPA1L1,HSPA5,NF2,SQSTM1,RHOU,DVL2,RPA3 |
| 3.401e-02 | -3.38 | glycosyl compound metabolic process | biological process | GO:1901657 | 84 | 33 | 18204 | 5365 |
PNP,APOBEC3D,APOBEC3A,MTAP,QNG1,NT5C3A,GNMT,APOBEC3F,AKR1B1,TYW3,APOBEC3H,NUDT1,DTYMK,APOBEC3C,AKR1C1,ERH,NT5C2,MACROD1,AKR1C2,DCTD,AKR7A2,DNPH1,APOBEC3B,CBR4,UCKL1,ADK,OARD1,NME4,ENPP4,TYW5,AKR1A1,APOBEC3G,ABHD10 |
| 3.406e-02 | -3.38 | mitotic metaphase chromosome alignment | biological process | GO:0007080 | 55 | 23 | 18204 | 5365 |
MIS12,CHMP2A,PSRC1,SKA2,CUL3,MAPRE1,NUP62,NUF2,CDC23,CHMP1B,NDC80,CHMP5,VPS4B,BECN1,SKA1,CHMP2B,CHMP4C,CCNB1,VPS4A,CHAMP1,CHMP1A,SKA3,RAB11A |
| 3.409e-02 | -3.38 | negative regulation of lipid storage | biological process | GO:0010888 | 22 | 11 | 18204 | 5365 |
ABHD5,PPARG,IL6,PPARA,LEP,MIR146A,OSBPL8,ITGAV,NFKBIA,TNF,NR1H2 |
| 3.413e-02 | -3.38 | TSPYL4 (TSPY like 4) | protein interactions | 23270 | 37 | 16 | 19454 | 5460 |
TFIP11,DCAF8L2,CDK5RAP3,NFKBIL1,MAGEA4,INSYN1,CCDC85B,NAP1L3,NF2,P4HA2,CMBL,ZNF655,AKAP1,PNMA1,NAP1L5,DFFA |
| 3.413e-02 | -3.38 | UROD (uroporphyrinogen decarboxylase) | protein interactions | 7389 | 37 | 16 | 19454 | 5460 |
NME1,CHRAC1,ATG3,PPID,RPA2,RIT1,MOV10,BAG3,RUNX1,FBXO7,ATG7,KRAS,APEX1,RPA3,FAF1,MTAP |
| 3.413e-02 | -3.38 | ALDH1L2 (aldehyde dehydrogenase 1 family member L2) | protein interactions | 160428 | 37 | 16 | 19454 | 5460 |
IMMP2L,HSCB,FZR1,CCNF,BAP1,PHB1,UBE2H,OTULIN,FAS,RHOG,PDHA1,TUBA1A,WDR11,ALDH1L1,GBE1,ATP5MG |
| 3.413e-02 | -3.38 | LINC00632 (long intergenic non-protein coding RNA 632) | protein interactions | 286411 | 37 | 16 | 19454 | 5460 |
PGRMC1,ANP32A,ACO2,LAP3,RPLP0,ACTR2,GDI2,RRAS2,UGDH,GNB1,LMAN1,LGALS3,HSPE1,RAB1B,PSMA1,CTSB |
| 3.413e-02 | -3.38 | AUTS2 (activator of transcription and developmental regulator AUTS2) | protein interactions | 26053 | 37 | 16 | 19454 | 5460 |
PCGF3,FANCD2OS,ZNF609,HNRNPL,NUP35,PCGF6,RERE,RSRC1,EP300,YAF2,CSNK2B,RING1,HAPSTR1,RPL18,HNRNPC,CSNK2A1 |
| 3.413e-02 | -3.38 | ORF21 (ORF21) | protein interactions | 4961484 | 37 | 16 | 19454 | 5460 |
CDC23,YPEL5,HTRA2,ARMC8,LUC7L3,CPSF2,PPP2R3A,PAIP1,SNX18,THRAP3,KCTD17,RANBP10,GID4,MAEA,GID8,MKLN1 |
| 3.413e-02 | -3.38 | IL20RA (interleukin 20 receptor subunit alpha) | protein interactions | 53832 | 37 | 16 | 19454 | 5460 |
TNIK,SNX17,STX5,VRK1,UBB,ROCK1,TAF7,PIK3R1,PIK3R3,BET1,RHEB,CYB5R1,DIRAS1,PIK3CA,C2CD2L,CERK |
| 3.413e-02 | -3.38 | ITPRIPL1 (ITPRIP like 1) | protein interactions | 150771 | 37 | 16 | 19454 | 5460 |
BVES,CDSN,S1PR4,CD63,VIPR1,LPAR2,RTN4,SPINT2,SGTA,VAPB,CD226,CHST7,CHRM3,TRAF2,HCST,STK4 |
| 3.415e-02 | -3.38 | SP100 (SP100 nuclear antigen) | protein interactions | 6672 | 199 | 68 | 19454 | 5460 |
TRIM29,ESR2,PPP1R10,CBX5,TOM1L1,CMTR1,PSPC1,MACROH2A1,SFXN2,UBE2I,CHTOP,H1-10,MECP2,DNAJB6,COP1,NOP16,CREBBP,NONO,RALGAPA2,HMGB1,PML,BIRC2,LSM12,NUFIP2,MFAP1,DYRK2,SUMO1,MX1,SUMO3,SUMO2,TOP1,ZNF740,NUF2,DBT,TRAF3IP3,MYEF2,RPL8,COQ8A,SEC23A,IGBP1,DSTN,CRTAP,TUBG1,FOXP1,AKAP8L,ACOT8,MOV10,IFI16,TMA16,PPIL4,ZNF609,RIGI,AHCYL1,FOXP4,MEPCE,GARRE1,SNIP1,RPL23A,SLC39A7,FAM76B,PNMA2,CBX3,DDX42,CRKL,PHC1,RBPJ,TP53,RPL29 |
| 3.418e-02 | -3.38 | MIRLET7G (microRNA let-7g) | protein interactions | 406890 | 116 | 42 | 19454 | 5460 |
CDC5L,CSTF3,HNRNPL,FAM98A,MATR3,SF3B4,MYEF2,RBM5,EIF2AK2,SYNCRIP,CPSF1,IGF2BP1,DDX1,CRTAP,DDX23,TRA2A,NONO,HNRNPA1,RBM17,APOBEC3B,SUGP1,KARS1,GRSF1,G3BP2,MARS1,CCAR1,HNRNPK,HNRNPA0,TRA2B,CDC40,HNRNPF,RTCB,HNRNPH2,SF3B1,HNRNPA2B1,NUFIP2,RARS1,SF3B5,HNRNPH3,RBFOX2,SF3A1,STRBP |
| 3.418e-02 | -3.38 | THEM6 (thioesterase superfamily member 6) | protein interactions | 51337 | 116 | 42 | 19454 | 5460 |
TSPAN17,LPAR2,TMEM106B,TSPAN15,RPA3,NT5C3A,SRPRB,HSCB,LGR4,ST7,CFTR,CDC42,RND2,OTULINL,DNAJC25,TMEM231,GP9,RPA2,LMNA,RAC2,RMDN3,RETREG3,S1PR4,LMBR1L,PTPN1,CCNF,SEC63,B4GAT1,ESR2,APLNR,EGLN3,RHOH,RHOJ,TAX1BP1,DNAJC1,DDRGK1,MTMR12,CUL3,NTRK3,ESYT1,RHOB,HFE |
| 3.418e-02 | -3.38 | FCGRT (Fc gamma receptor and transporter) | protein interactions | 2217 | 116 | 42 | 19454 | 5460 |
HFE,LRP6,BAX,PMP22,RAB11A,NAA50,CMSS1,CDC123,BTF3L4,GTF2E1,SCGB1D1,SNX3,TNPO3,CITED1,CBX5,SURF2,CD1E,SERPINC1,ALB,LDLR,RAB4A,PCDH17,CHMP1A,FGFR1,QRSL1,FAM3C,FURIN,SH3GLB1,ATG16L1,TNPO2,UBLCP1,CD1B,CNTN1,B2M,UTP25,RWDD4,CLU,ITM2B,METTL18,DUSP9,MTDH,DERL1 |
| 3.418e-02 | -3.38 | RBBP8 (RB binding protein 8, endonuclease) | protein interactions | 5932 | 116 | 42 | 19454 | 5460 |
EXD2,NBN,PCNA,TGIF2,KLHL15,KDM1A,PELI1,FXR2,DHX16,HSPA5,CLU,FTL,BRIX1,RAF1,H2AX,EEF1A1,LMO4,MED23,CTBP1,CTNNA2,SDCBP,RPA2,THOC2,RPL32,PHF21A,UBE2I,RB1,FZR1,SPPL3,SIAH1,SNRNP40,MDM2,HSP90AB1,TAX1BP3,LMO2,CUL3,NTAQ1,SIAH2,RBBP8,BRCA1,COP1,TOPBP1 |
| 3.421e-02 | -3.38 | nervous system development | biological process | GO:0007399 | 2185 | 681 | 18204 | 5365 |
GNB4,MACO1,FAM151B,NOVA1,THY1,ATF4,LEP,PMP22,EXT1,NEGR1,PDSS2,SERPINI1,MGARP,NME1,NDE1,MTMR2,CDK20,IGSF21,DAG1,SLC25A46,SRC,C1QL3,HOXB8,ROCK1,P2RY12,LYPLA2,NEO1,MEF2A,MIR135B,MPZ,ETV6,GNPAT,PAFAH1B1,IFT52,CAMSAP2,TIAM1,ATP5PB,GPR37,DYNLL1,BMERB1,NDUFS2,ZC4H2,DOK5,NLGN1,FIG4,NTF4,IFNG,SOX14,NTRK3,MYT1L,STMN2,FLRT2,NTRK2,NIBAN2,FZD4,TRNP1,BLOC1S5,NBN,CAMK1,PCDHB13,METTL14,EIF2B5,WDR19,RAN,NR2E1,NR0B1,RAPGEF5,PQBP1,ITM2B,TRIM3,AMIGO1,PRKACB,INSM2,YWHAZ,FOXP2,TRAPPC4,ADGRG1,SLC38A2,SEMA7A,VEGFA,TAL2,NF2,MOG,PTS,NCDN,SOX3,MTPN,BMPR1A,SLITRK1,RRM1,SIGMAR1,SMARCB1,EFHC1,MECP2,LLPH,S100A8,FCGR2B,RPS7,NOG,HDAC6,ZDHHC17,ELP3,STK11,CLU,CCR4,PROM1,OMG,MACROH2A2,ACVR1B,TRIM32,WNT2,HNRNPD,CYB5D2,TMEM108,RAP1A,SLITRK2,GIT2,FA2H,NIF3L1,SPTBN1,NR2F6,SLC2A1,SLC7A11,ATG16L1,SARM1,KCNJ10,SCN3B,SCYL2,RAB35,NTN4,LRTM2,PICK1,VPS54,BPGM,NRN1,XRCC5,FEZ1,NINJ1,NPTX1,CD2AP,CLRN2,ZDHHC16,MYLIP,G6PD,TLR2,MARCKSL1,TRAF6,NLGN2,POU3F4,FXR2,GLRB,FKTN,NDP,CYP1B1,B3GNT2,FUT9,RPL24,CHRM3,SSNA1,DRD1,KCNJ8,EFHD1,PLP1,FGF13,BMPR1B,NHERF1,JRKL,IGF2BP1,IRF2BPL,FOS,TAFA1,SYNGR3,CCL2,UGP2,SLC11A2,DISC1,SYBU,POU1F1,CBLN4,IQSEC1,NEUROD2,SMARCE1,IFNGR1,FLOT1,MAP4,VEGFC,EMX2,GPR37L1,SLC1A3,SMN1,OTX2,AKT2,ACTL6A,KCNA2,COPS2,SCLT1,PPP1R17,ATXN10,AKT3,UHMK1,FOXP3,GRIK1,FUT1,SDC2,HEXA,BAX,EIF4E,IL6,SLITRK5,HAPLN2,PCDHA5,ID4,CSK,NDST1,PCDH17,BGLAP,ASPM,UBB,COX6B1,DEGS1,SOX21,PADI2,CRMP1,MYO6,FOXP1,IMMP2L,GPM6B,THOC6,ACSL4,ACVR1C,ALCAM,LDB2,UBE3A,MMP14,LRRC4,CPNE1,UQCRQ,SEMA4C,PAFAH1B3,ANAPC2,CD9,TNIK,ECRG4,RBFOX3,PLCB1,ESS2,SMARCD3,DNM2,ORMDL1,RTN4,ZBTB16,ZNF24,LST1,OLFM3,SNAPIN,SLC32A1,UCN,DRP2,GJA10,HHIP,NDUFS3,SSBP3,SIN3A,PAX6,CLDN11,TRAPPC6B,WNT10B,EDNRA,NYAP2,SEMA3C,GPC1,CEND1,SMAD4,FKRP,ELAVL4,NPY,WNT7A,CLP1,PPP3CA,AKT1,CA10,MIOS,NDNF,IL1B,RBBP4,CTNNB1,SLC1A1,PCDH9,NPR2,MAP1B,SLC1A2,GSTP1,PRPS1,B4GAT1,NEUROD6,CYFIP2,OXTR,TOX,RALA,HMX2,EP300,CERS6,RNF103,DIO3,BOK,ASPA,CAMK2G,CCND1,PAK2,TGFBR2,PLAA,SOD1,RND2,CNR1,KIF2A,CRKL,XBP1,GRIA1,LMO4,MET,TIMM8A,ANP32B,FLRT3,DVL2,VXN,CDK5RAP3,L1CAM,CPLX2,GSK3A,ACER3,RGMA,ROGDI,UGCG,TUBA1A,CKB,PTEN,MCPH1,JAK2,STXBP1,MIR125A,VLDLR,RPGRIP1L,MATCAP1,NRP1,PCSK9,LRP6,SELENOP,ENC1,C1QL1,SMG9,HDAC11,PTPN11,ARF4,CDK6,ASTN1,UGDH,SLC4A10,TLR4,DLG4,CER1,SRSF1,FGFR1,P2RY1,ATXN1L,ACKR3,MARVELD1,TBCE,HELT,COMT,RAD1,BRINP2,LARGE1,LAMB2,ADORA1,HSPA8,NRGN,SCN1B,EPOP,NDUFV2,SOD2,LEPR,TMEM14B,FTSJ1,CNP,EHD1,CFAP418,GABRA1,BRINP1,NRSN1,SDCBP,ACTL6B,LPAR1,SDC4,BLOC1S2,STK4,SVBP,ERCC3,HTR5A,TP53,RRAS2,MAP1S,FKBP8,ST8SIA4,RACGAP1,EMX1,CLSTN3,ARCN1,B4GALT6,S100A6,CCDC134,TSPO,BTG2,IMPACT,PRKCQ,NREP,SUFU,FZD6,NCSTN,CAPG,LHX2,ATAT1,EIF2B2,EZH1,CHRNA7,HEXB,CHRNB2,IL3,UPF3B,IER2,EZH2,NR4A2,TRAK2,CLN8,CNTN2,MNAT1,TPBG,S100B,SLC6A4,GABRA2,PLPPR1,GPM6A,IL34,MYRF,MKKS,SIAH1,EPHB6,BCCIP,TBC1D24,CXCR4,MAMDC2,MOBP,TRIM46,PITPNA,AGER,HRAS,CHRDL1,DUSP10,CORO1C,TOP2B,ORMDL3,GABRB3,HMGB1,CXCL12,BCL6,KLK6,EPHA2,PTK7,RAB6A,PHACTR1,LBX1,CDK5,NTNG2,CDKN2C,NKX6-2,TAGLN3,MSX1,CX3CR1,ATL1,CNTNAP1,RAB6B,TMEM106B,RAB11A,TWSG1,ACTB,GALC,TNF,RBBP7,FGF17,CX3CL1,RAF1,NGRN,FERD3L,NAB2,PPT1,RBPJ,ALDH1A3,POMT2,ARF6,INA,CLDN3,NHEJ1,NEUROG2,UFM1,CDH11,TENM3,TMEM126A,NEFL,GJA1,DDR1,SCN2B,MYEF2,CNTN1,LDB1,ASIC2,TMEM107,ILK,NAB1,H2AX,ZBTB45,TRA2B,FBXW11,LGI1,ZNF365,RB1,CTTN,CITED1,ADNP,FOLR1,KCNA3,MPST,SPHK2,NDN,DRGX,RFX4,EED,UNC119B,CDNF,HSP90AA1,TGIF2,CDK5R1,C1QL2,SNAP25,STK3,FGF12,KDM4B,YWHAH,RAB18,CCL3,HNF1B,BCL10,LNX2,ATP6AP2,CNTFR,PCSK2,LY6H,IFT172,SFRP1,CREB1,IGF1R,CDC42,PPIA,CDC20,SEMA6C,GPR17,COX7B,EFNA3,KCNC1,GSTM3,RORB,ADD2,NELL2,KCNB1,DNAJC30,THOC2,EPHA4,DLX1,CBLN2,CLDN1,PTN,PSEN1,EGR2,TULP3,GABRB2,OR10A4,BEND6,HTRA2,OPHN1,RUNX1,HSPA5,WWP1,NRSN2,MYD88,IFT57,NPTN,BLOC1S3,CMA1,PTPRZ1,MEF2C,EFNA5,ACHE,DOK4,COQ8B,ADGRL3,TYROBP,RBFOX2,SHC3,WDR37,VPS4B,SEMA5A,TPPP,DDIT4,CXCL1,HAND2,C9orf72,PROX1,WASF3,PCDHB8,GAS8,SPINT2,SOX2,COL3A1,GAL3ST1,WASL,FABP7,SPOCK1,DKK1,DYRK1A,HOXB1,PEX13,FGF10,GABRG2,RERE,GJB1,RAB29,LIAS,HYCC1,EIF2B3,MBD5,KRAS,NOTCH2,SLC6A3,GRXCR1,TGFB2,PAK6,PCDHB1,BECN1,EFNB1,DICER1,NAPA,CBLN1,ATP1A2,RAB13,BRINP3,PICALM,RAB3A,GHRL,TNR,MTF1,FZD3,CTNNA1,SOX9,CTNNA2,RHEB,ABITRAM,ATP5PF,PPP1CC,MAP2K1,HDAC5,ACTL9,TMX2,KCNIP2,LRP12,CLRN1,ATP2B4,CHRM1,SMAD1,TTC8,NCKAP1,KLHL1,KDM1A,TMOD2 |
| 3.422e-02 | -3.38 | Thioredoxin_CS | interpro domains | IPR017937 | 17 | 9 | 18521 | 5414 |
PDIA3,TXN,PDIA6,TXNL1,TXNDC12,DNAJC10,TMX3,PDIA2,TMX4 |
| 3.424e-02 | -3.37 | KLHL5 (kelch like family member 5) | protein interactions | 51088 | 15 | 8 | 19454 | 5460 |
GABARAPL2,MAP1LC3B,CUL3,SMN1,KLHL12,CBL,KLHL1,SKA2 |
| 3.424e-02 | -3.37 | MYH15 (myosin heavy chain 15) | protein interactions | 22989 | 15 | 8 | 19454 | 5460 |
STK4,ACTN4,MYL12B,MYC,H2AZ1,STK3,FLOT1,FTL |
| 3.424e-02 | -3.37 | RL1 (neurovirulence protein ICP34.5) | protein interactions | 2703395 | 15 | 8 | 19454 | 5460 |
RPS27L,BECN1,TUBB,RIGI,RPL23,RPL17,ACTA2,TUBA1A |
| 3.424e-02 | -3.37 | LEMD1 (LEM domain containing 1) | protein interactions | 93273 | 15 | 8 | 19454 | 5460 |
JAGN1,BLCAP,SCN3B,RETREG3,SPPL3,MGST3,REEP4,ZDHHC15 |
| 3.424e-02 | -3.37 | COQ10B (coenzyme Q10B) | protein interactions | 80219 | 15 | 8 | 19454 | 5460 |
CHCHD2,POLDIP2,FTL,ESR2,STOML2,TIMM8B,CLPB,DDX39A |
| 3.424e-02 | -3.37 | PTPRCAP (protein tyrosine phosphatase receptor type C associated protein) | protein interactions | 5790 | 15 | 8 | 19454 | 5460 |
EEF1A1,ODR4,STX10,STX5,PGRMC1,OSBPL8,GOSR1,CMTM6 |
| 3.424e-02 | -3.37 | Brca1 (breast cancer 1, early onset) | protein interactions | 12189 | 15 | 8 | 19454 | 5460 |
SMCHD1,UBE2D3,DNPH1,CETN2,SCLT1,BAD,NDST1,ABCE1 |
| 3.424e-02 | -3.37 | IGSF1 (immunoglobulin superfamily member 1) | protein interactions | 3547 | 15 | 8 | 19454 | 5460 |
RPL8,BMPR1B,BMPR1A,IGF1,ACVR1B,ACVR1,RANBP10,HECTD1 |
| 3.424e-02 | -3.37 | PREX2 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2) | protein interactions | 80243 | 15 | 8 | 19454 | 5460 |
PDHA1,HUWE1,RHOG,GNMT,LDLR,NT5C2,CDC42,H2BC9 |
| 3.424e-02 | -3.37 | PRR16 (proline rich 16) | protein interactions | 51334 | 15 | 8 | 19454 | 5460 |
SMURF1,SPPL3,DAPK1,DDX39A,PPP1CC,ERP29,DLG4,GCLC |
| 3.424e-02 | -3.37 | DTWD1 (DTW domain containing 1) | protein interactions | 56986 | 15 | 8 | 19454 | 5460 |
DAPK1,SLC31A1,HBB,PTP4A3,MAD2L2,ACTA2,HP,NUBP2 |
| 3.424e-02 | -3.37 | GLIPR1 (GLI pathogenesis related 1) | protein interactions | 11010 | 15 | 8 | 19454 | 5460 |
CMTM6,HBB,CKLF,HSPA5,RPS29,SF3B4,SOX2,HSPA8 |
| 3.424e-02 | -3.37 | ZBTB7C (zinc finger and BTB domain containing 7C) | protein interactions | 201501 | 15 | 8 | 19454 | 5460 |
PIP5K1A,JUN,HSCB,ZBTB17,CDC5L,MBD3,PIAS1,ZBTB5 |
| 3.424e-02 | -3.37 | SERGEF (secretion regulating guanine nucleotide exchange factor) | protein interactions | 26297 | 15 | 8 | 19454 | 5460 |
PRMT6,DPH3,BFAR,EXOC2,KDM1A,BLOC1S5,HGS,FERMT2 |
| 3.424e-02 | -3.37 | EFCAB11 (EF-hand calcium binding domain 11) | protein interactions | 90141 | 15 | 8 | 19454 | 5460 |
CETN3,AKR1B1,CFTR,MOV10,DLG1,UBB,CETN2,CASK |
| 3.424e-02 | -3.37 | PIANP (PILR alpha associated neural protein) | protein interactions | 196500 | 15 | 8 | 19454 | 5460 |
GALNT12,GALNT4,TMBIM6,AKT3,TCAF2,CMTM7,GALNT2,GHITM |
| 3.424e-02 | -3.37 | ELMOD3 (ELMO domain containing 3) | protein interactions | 84173 | 15 | 8 | 19454 | 5460 |
CSK,HRAS,MAP1S,KRAS,DIRAS3,ACACA,RIGI,APEX1 |
| 3.425e-02 | -3.37 | ErbB1 downstream signaling | Pathway Interaction DB | erbb1_downstream_pathway | 102 | 45 | 2226 | 782 |
DUSP1,RAB5A,NCKAP1,ACTR2,AKT1,GAB1,YWHAB,ELK1,VAV2,MYC,PIK3R1,SMAD1,FOS,PPP2R1A,RAF1,YWHAH,EPS8,ARPC2,ARPC3,RALA,ARF4,STAT1,EGR1,PPP5C,PEBP1,SFN,ATF1,CDC42,SRC,MEF2C,YWHAZ,CYFIP2,USP6NL,DUSP6,BAD,CHN2,JUN,CAPN2,YWHAG,WASL,MAP2K1,RPS6KA4,PRKCA,PIK3CA,CREB1 |
| 3.427e-02 | -3.37 | Nucleotide-like (purinergic) receptors | REACTOME pathways | R-HSA-418038 | 16 | 9 | 10285 | 3229 |
P2RY4,P2RY12,LPAR6,P2RY10,GPR17,P2RY1,ADORA1,ADORA3,P2RY11 |
| 3.427e-02 | -3.37 | Regulation of TLR by endogenous ligand | REACTOME pathways | R-HSA-5686938 | 16 | 9 | 10285 | 3229 |
CD14,TLR4,TLR1,TLR6,S100A8,CD36,TLR2,LY96,HMGB1 |
| 3.427e-02 | -3.37 | channel regulator activity | molecular function | GO:0016247 | 145 | 54 | 18094 | 5411 |
DLG1,PDE4B,KCNMB1,NPY,KCNMB2,TMEM168,FXYD6,RANGRF,AMIGO1,ARPP19,DPP10,SRI,CACNG3,FGF13,GRM2,CHRNA7,FKBP1A,KCNAB1,SCN1B,AKT1,VAMP8,SCLT1,KCNIP3,VTI1B,SCN3B,CAV1,PRKCB,FKBP1B,SUMO1,NPY2R,FGF12,GLRX,SNTA1,SCN2B,ATP2B4,STX7,STIM1,CFTR,KCNIP2,CAV3,LYNX1,STX8,YWHAH,STOM,CRISP1,NHERF1,PACSIN3,PCSK9,ADRB2,LAMP2,KCNS1,STX1A,CACNB3,CHP1 |
| 3.435e-02 | -3.37 | MPHOSPH8 (M-phase phosphoprotein 8) | protein interactions | 54737 | 88 | 33 | 19454 | 5460 |
MYC,MOV10,IFI16,BTF3,MRPL18,RPL24,ZNF330,ENO1,MATR3,TOP1,HECW1,RPP25L,CGAS,SH3BP4,ERH,LRWD1,ESR2,ATG16L1,IMP3,ESAM,YIPF5,METTL14,RPS11,TBC1D4,ZNF770,NCOA5,MCRIP2,ATP5MK,TSR3,H3C1,TMEM33,SSRP1,UTP23 |
| 3.435e-02 | -3.37 | RNMT (RNA guanine-7 methyltransferase) | protein interactions | 8731 | 88 | 33 | 19454 | 5460 |
COPS5,AR,KPNA6,MYC,CUL3,CUL2,KPNA1,UBE2H,RIT1,CCT2,BRCA1,ATG3,SMAD3,EIF4E2,MAT2B,NCBP2,CCT7,CAND1,DCUN1D1,HEXA,ARHGAP1,HNRNPH3,HEXB,RPA2,RPRD1B,HSPA8,RAMAC,DDR1,EIF4E,MDC1,KRAS,KPNA2,SRM |
| 3.435e-02 | -3.37 | Cluh (clustered mitochondria homolog) | protein interactions | 74148 | 88 | 33 | 19454 | 5460 |
RPS4X,SRSF4,STAU1,NRGN,HADHA,SNIP1,HSPD1,MCRIP2,PDHA1,METTL15,CDC42,PCK2,ATP5PB,AKAP17A,SUCLG2,POLR2B,USP16,ACAT1,WDR82,DLST,HDHD5,UQCRC2,UBE2H,OAT,H1-10,PHKA1,ATP5F1A,MTPN,RPL26,RPL7A,SPATS2L,MAT2A,ACO2 |
| 3.435e-02 | -3.37 | GNL1 (G protein nucleolar 1 (putative)) | protein interactions | 2794 | 88 | 33 | 19454 | 5460 |
KRR1,FBXO32,ALYREF,WDCP,FAU,SRP14,GTF2F1,CSNK2B,DYNC1I2,RPL7,NOP58,RPL19,HNRNPC,CSNK2A1,SMAD4,DNAJB6,TCOF1,RPA3,HINT1,EP300,PGK1,RUVBL2,HSPA8,RPL4,EIF5B,HUWE1,AHCYL1,RAD21,RAF1,TULP3,TUBB4B,RPA2,RPLP0 |
| 3.435e-02 | -3.37 | C2CD5 (C2 calcium dependent domain containing 5) | protein interactions | 9847 | 88 | 33 | 19454 | 5460 |
CDK9,RHOJ,RHOH,SYT2,RAC2,SYNCRIP,RAB35,CCNF,TNFRSF1B,DNAJC7,CDK12,HNRNPD,BRD3,RHOG,RHOB,RACGAP1,ZCCHC10,RAB5C,TACR3,IL13,SLC5A6,KRAS,FGF12,HAPSTR1,CDK5,PICK1,EP300,RHOU,AVPR1B,RND3,RPA2,CDC42,RND2 |
| 3.448e-02 | -3.37 | SOX15 (SRY-box transcription factor 15) | protein interactions | 6665 | 135 | 48 | 19454 | 5460 |
MRPS23,HMG20A,TOP1,HP1BP3,MRPS9,SSBP1,MRTO4,KRR1,FOXP1,SMCHD1,DNTTIP1,TSEN34,MOV10,DDX50,TLE1,MRPS17,RPS13,FOXP4,ZNF609,SATB1,MRPS18B,BCL9,BHLHE40,LSM14A,PPAN,ILF2,SSBP3,SRP72,RBM34,TRMT1L,TP53,MRPL11,ATXN1L,IGF2BP1,MRPS16,LMNB1,LDB1,HNF1B,MRPS7,BRIX1,NOP53,STAU1,MRPL40,EP300,HADHA,E2F6,MRPS34,CFTR |
| 3.448e-02 | -3.37 | BOD1L1 (biorientation of chromosomes in cell division 1 like 1) | protein interactions | 259282 | 135 | 48 | 19454 | 5460 |
PSMD1,MYC,ZMAT5,GTF2F1,PSMA6,VIRMA,ESR2,MAD2L1,TRIM29,BUB3,CNPY3,SEC22B,AKR7A2,MYL6,ADNP,GRM2,RPA2,VAV2,NUP50,HCFC2,RPA3,CXXC1,STAU1,EIF5B,SGF29,COPS5,YWHAG,YWHAH,KPNA1,SKIC8,WDR82,SIN3A,KLHL7,SUMO2,HNRNPL,TNPO2,SOX2,ANAPC13,CENPM,EZH2,BAG2,MAP1B,PRPS1,COPS4,MDC1,TOLLIP,KPNA2,PSMA1 |
| 3.448e-02 | -3.37 | JAK3 (Janus kinase 3) | protein interactions | 3718 | 135 | 48 | 19454 | 5460 |
DCK,MAGED2,COX4I1,GTF2B,HSP90AB1,TCP1,CISH,CD81,PIK3R1,CD247,BAG2,JAK1,CCT8,PTGES3,SOCS2,KIT,DHX16,SOCS3,CDK4,CSNK1E,TOP3B,CAPN2,GEMIN7,PRMT5,STUB1,OPTN,TNPO3,NMI,JAK2,STAT5A,MRPL23,IL2RB,RAB11A,HSP90AA1,LACRT,SMPD2,CCT2,LCN1,CRY1,CXCR4,CD40,PIK3R2,IL2RG,PRKAB1,STAT6,UBE2M,LEPR,CDK1 |
| 3.448e-02 | -3.37 | CEP350 (centrosomal protein 350) | protein interactions | 9857 | 135 | 48 | 19454 | 5460 |
TRIM52,STAU1,KDM1A,RNF10,SQSTM1,TRIM36,PPARG,RPA2,ATG16L1,VIRMA,RPGRIP1L,ANAPC2,GSK3A,CTNNA1,MAPRE1,BRCA1,DCAF4,ATP5F1A,RNF40,SFN,CEP85,CDC16,TRIM37,ZYX,APTX,DISC1,PNMA2,PPARA,PPP2R1A,TP53,RAF1,CEP19,EGLN3,RABL2B,PRNP,KRT8,ARL10,PPP2CB,YWHAB,CAMSAP2,SSX2IP,MED4,SPATA2,YWHAH,XPO1,YWHAG,NDC80,MOV10 |
| 3.449e-02 | -3.37 | TNFRSF17 (TNF receptor superfamily member 17) | protein interactions | 608 | 23 | 11 | 19454 | 5460 |
TNFSF13,ZMPSTE24,AGPAT1,CMTM7,TRAF6,TMBIM6,OTULINL,TRAF2,ORC5,TRAF1,OPA3 |
| 3.449e-02 | -3.37 | SLITRK4 (SLIT and NTRK like family member 4) | protein interactions | 139065 | 23 | 11 | 19454 | 5460 |
FBXO22,RHOH,RHOJ,RAC2,RHOU,RND3,RHOG,RHOB,RND2,CNPY3,CDC42 |
| 3.449e-02 | -3.37 | Poc1b (POC1 centriolar protein B) | protein interactions | 382406 | 23 | 11 | 19454 | 5460 |
EXOC3,STOM,TMOD3,HNRNPK,GNAI2,FOLR1,GNG12,PPP1R12A,POC1B,CORO1C,SQSTM1 |
| 3.449e-02 | -3.37 | SIM2 (SIM bHLH transcription factor 2) | protein interactions | 6493 | 23 | 11 | 19454 | 5460 |
MATR3,PPP5C,RIGI,PTGES3,MAD2L2,PAX6,DNAJB4,HSPA8,BRCA1,EPO,HSP90AA1 |
| 3.449e-02 | -3.37 | ERAP2 (endoplasmic reticulum aminopeptidase 2) | protein interactions | 64167 | 23 | 11 | 19454 | 5460 |
MTCH2,DNAJC10,RPA2,SEC61B,AKAP1,RPL27,DNAJC3,RPA3,RIGI,HSPA5,DNAJC30 |
| 3.449e-02 | -3.37 | DHRSX (dehydrogenase/reductase X-linked) | protein interactions | 207063 | 23 | 11 | 19454 | 5460 |
RUSF1,HSD17B11,RETREG3,ZBED1,GCNT3,HNRNPL,TLCD4,CIDEB,TMEM31,ZDHHC15,TMEM14B |
| 3.449e-02 | -3.37 | BPIFA2 (BPI fold containing family A member 2) | protein interactions | 140683 | 23 | 11 | 19454 | 5460 |
HINT2,NKAP,CMTM6,PRKCE,JAK2,UQCRQ,AGTRAP,TIMM10,RHOBTB1,STK11,CCDC174 |
| 3.449e-02 | -3.37 | ERN2 (endoplasmic reticulum to nucleus signaling 2) | protein interactions | 10595 | 23 | 11 | 19454 | 5460 |
SDF2L1,HSP90B1,SELENOF,SERPINH1,HSPD1,DNAJC3,CSK,ISYNA1,GANAB,PDIA6,CNP |
| 3.449e-02 | -3.37 | CCDC71L (coiled-coil domain containing 71 like) | protein interactions | 168455 | 23 | 11 | 19454 | 5460 |
CHAMP1,CBX3,ADNP,TOP3B,LRIF1,CBX5,TNFSF12,CHCHD2,RPA3,CCDC71,ZNF330 |
| 3.449e-02 | -3.37 | UNC93A (unc-93 homolog A) | protein interactions | 54346 | 23 | 11 | 19454 | 5460 |
TMX2,RHAG,CDIPT,SYNGR1,SLC39A7,TMEM237,TIMMDC1,SLC48A1,FCER1G,TMEM14B,SLC35E4 |
| 3.449e-02 | -3.37 | TMEM62 (transmembrane protein 62) | protein interactions | 80021 | 23 | 11 | 19454 | 5460 |
HERC3,UFD1,CLEC12B,CSE1L,KLRC2,HSPA5,ZNF287,APEH,UPK1A,CDSN,CLRN2 |
| 3.449e-02 | -3.37 | CNST (consortin, connexin sorting protein) | protein interactions | 163882 | 23 | 11 | 19454 | 5460 |
DVL2,GJA1,HAPSTR1,EWSR1,SQSTM1,GJB1,VIRMA,GJC1,GJB2,BAG3,PPP1CC |
| 3.449e-02 | -3.37 | ZNF510 (zinc finger protein 510) | protein interactions | 22869 | 23 | 11 | 19454 | 5460 |
CCND1,CTNNA1,CSK,SMAD1,TGFBR2,FBXW7,ODC1,MLH3,SMAD4,STK11,SMAD2 |
| 3.449e-02 | -3.37 | EDA2R (ectodysplasin A2 receptor) | protein interactions | 60401 | 23 | 11 | 19454 | 5460 |
TRAF6,KRAS,CEBPE,TRAF1,ICAM1,ATP2B4,PLP1,HSDL1,JAGN1,SGTA,TRAF2 |
| 3.449e-02 | -3.37 | DMAC1 (distal membrane arm assembly component 1) | protein interactions | 90871 | 23 | 11 | 19454 | 5460 |
TOMM22,MGARP,XPO1,ATP5F1A,HNRNPD,UBE2H,BAP1,SDHC,PGK1,KCTD10,PSMD12 |
| 3.449e-02 | -3.37 | DNASE1L2 (deoxyribonuclease 1 like 2) | protein interactions | 1775 | 23 | 11 | 19454 | 5460 |
POLL,BLVRA,HSPA5,RPL23,SLC25A21,FBXL4,PTDSS1,PHF13,SLC19A2,CSK,TRMT1L |
| 3.449e-02 | -3.37 | RAPGEF4 (Rap guanine nucleotide exchange factor 4) | protein interactions | 11069 | 23 | 11 | 19454 | 5460 |
FBXO22,RADX,PSMD14,RIGI,BMERB1,SWAP70,RAP1A,RAP2A,TRAF2,RRAS2,ZC3H11A |
| 3.449e-02 | -3.37 | F5 (coagulation factor V) | protein interactions | 2153 | 23 | 11 | 19454 | 5460 |
CALR,PROS1,F2,F10,OLR1,CSNK2A1,SERPINA3,TNFSF8,MED4,SRPK2,NUPR1 |
| 3.449e-02 | -3.37 | UBXN2A (UBX domain protein 2A) | protein interactions | 165324 | 23 | 11 | 19454 | 5460 |
RIGI,NSFL1C,PHAX,STUB1,FAF1,VCPIP1,PPP1R11,UBXN10,PPP1CB,PPP1CC,UBXN6 |
| 3.449e-02 | -3.37 | NINJ1 (ninjurin 1) | protein interactions | 4814 | 23 | 11 | 19454 | 5460 |
CD200R1,CYB5R3,TIMMDC1,NINJ1,TMEM31,FNDC9,ESR2,FCGR1A,TLCD4,ATP6AP2,TMEM14B |
| 3.454e-02 | -3.37 | regulation of response to nutrient levels | biological process | GO:0032107 | 30 | 14 | 18204 | 5365 |
VDR,GHRL,NPY,SNAI2,UCN,BAX,MKKS,LEP,MT3,CARTPT,CYP27B1,PPARA,TRIM24,GHR |
| 3.454e-02 | -3.37 | nucleobase-containing small molecule catabolic process | biological process | GO:0034656 | 30 | 14 | 18204 | 5365 |
MGAT1,APOBEC3C,APOBEC3H,APOBEC3G,NUDT1,APOBEC3F,ENPP4,ENTPD4,DCTD,MTAP,APOBEC3B,APOBEC3A,PNP,APOBEC3D |
| 3.454e-02 | -3.37 | steroid hormone biosynthetic process | biological process | GO:0120178 | 30 | 14 | 18204 | 5365 |
TSPO,HSD17B11,CYP11B2,DHRS11,CYP17A1,LHB,SRD5A3,HSD17B3,CYP11B1,CYP21A2,HSD17B8,HSD17B1,AKR1B1,HSD17B6 |
| 3.455e-02 | -3.37 | protein localization to nucleus | biological process | GO:0034504 | 190 | 68 | 18204 | 5365 |
ING1,TXN,MSX1,TRAF3IP2,SEC13,NUP107,KPNA1,CALR,TP53,RANBP6,XPO1,STK4,MDM2,NFKBIA,SQSTM1,STK3,STK11,TOR1B,LMNB1,UTP25,TMEM147,RPAIN,PHB2,HIKESHI,HSPA8,CDK5,WRAP53,NOP53,AKT1,RRP7A,PPP3CA,RANGRF,FAM53B,LMNA,TNPO2,SYK,IPO8,NUP35,SUPT7L,OSBPL8,SUMO1,DRD1,KPNA6,CDKN1A,TXNIP,PML,NUP62,ARL2BP,KPNA2,SPRN,CSE1L,RPF2,PPP1R10,RPL23,POLA2,DNAJB6,TOR1AIP2,SKP1,NUP50,NUP153,TOPORS,PGR,SOX9,ZBTB16,FAM53C,TNPO3,PIK3R1,RAN |
| 3.455e-02 | -3.37 | pallium development | biological process | GO:0021543 | 190 | 68 | 18204 | 5365 |
FXR2,FOXP2,PLCB1,NEFL,NR2E1,RAN,BTG2,GRIA1,RTN4,FEZ1,PSEN1,CRKL,EIF2B5,POMT2,UQCRQ,EMX1,NTRK2,KDM1A,MKKS,MECP2,EFHC1,ATP2B4,IGF2BP1,MCPH1,PTEN,PAX6,DISC1,LHX2,ATAT1,NF2,EZH1,FGF13,EZH2,TUBA1A,SLC32A1,ADGRG1,SLC38A2,H2AX,DRD1,TRA2B,LARGE1,PEX13,CDK5,PHACTR1,KCNA2,MGARP,NPY,COL3A1,NDE1,CDK5R1,CDK6,PROX1,EMX2,BMERB1,HTR5A,DLX1,PAFAH1B1,SLC2A1,ATG16L1,NEUROD6,ASPM,TMEM14B,CTNNB1,P2RY12,BAX,TMEM108,IGF1R,ID4 |
| 3.455e-02 | -3.37 | HMCN1 (hemicentin 1) | protein interactions | 83872 | 10 | 6 | 19454 | 5460 |
WDR77,B2M,DVL2,CUL3,DDX1,CLP1 |
| 3.455e-02 | -3.37 | ORF70 (ORF70) | protein interactions | 4961481 | 10 | 6 | 19454 | 5460 |
DLAT,TYMS,DLST,TOMM70,PDHA1,KGD4 |
| 3.455e-02 | -3.37 | Emc3 (ER membrane protein complex subunit 3) | protein interactions | 66087 | 10 | 6 | 19454 | 5460 |
TMEM237,EMC8,EMC1,EMC2,STOML2,EMC4 |
| 3.455e-02 | -3.37 | Sirt2 (sirtuin 2) | protein interactions | 64383 | 10 | 6 | 19454 | 5460 |
CDC20,CDC23,ANAPC4,FZR1,EP300,CDC16 |
| 3.455e-02 | -3.37 | Hspa8 (heat shock protein family A (Hsp70) member 8) | protein interactions | 24468 | 10 | 6 | 19454 | 5460 |
DNAJC7,SOST,TTC1,SGTA,BAG3,PRDX1 |
| 3.455e-02 | -3.37 | IPCEF1 (interaction protein for cytohesin exchange factors 1) | protein interactions | 26034 | 10 | 6 | 19454 | 5460 |
CCDC92,CYTH4,CYTH2,CYTH1,TRIM11,CEP70 |
| 3.455e-02 | -3.37 | MYO18B (myosin XVIIIB) | protein interactions | 84700 | 10 | 6 | 19454 | 5460 |
STAU1,ACTB,PSMC5,TULP3,SRPK2,RAC2 |
| 3.455e-02 | -3.37 | ALS2CL (ALS2 C-terminal like) | protein interactions | 259173 | 10 | 6 | 19454 | 5460 |
RAB5A,RAB22A,EEF1AKMT3,RAB5C,RAB31,NF2 |
| 3.455e-02 | -3.37 | HEG1 (heart development protein with EGF like domains 1) | protein interactions | 57493 | 10 | 6 | 19454 | 5460 |
TOP3B,RAB11A,VIRMA,LGALS8,KRIT1,LGALS3 |
| 3.455e-02 | -3.37 | STOML3 (stomatin like 3) | protein interactions | 161003 | 10 | 6 | 19454 | 5460 |
CAV1,ADCY3,JAGN1,TP53,SEC22A,ZDHHC24 |
| 3.455e-02 | -3.37 | SOX21 (SRY-box transcription factor 21) | protein interactions | 11166 | 10 | 6 | 19454 | 5460 |
POU5F1,HAPSTR1,EWSR1,SOX2,APPBP2,RIOX2 |
| 3.455e-02 | -3.37 | CREBRF (CREB3 regulatory factor) | protein interactions | 153222 | 10 | 6 | 19454 | 5460 |
ATF1,HSPA8,CD2BP2,CREBL2,VIRMA,NAA11 |
| 3.455e-02 | -3.37 | PKHD1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin) | protein interactions | 5314 | 10 | 6 | 19454 | 5460 |
LGR4,RPLP2,CAMLG,SMURF1,PSMD14,PRKAG1 |
| 3.455e-02 | -3.37 | SPAG11A (sperm associated antigen 11A) | protein interactions | 653423 | 10 | 6 | 19454 | 5460 |
MKLN1,ZMYND19,MAEA,ITGAV,FAM118B,HSPA5 |
| 3.455e-02 | -3.37 | CA3 (carbonic anhydrase 3) | protein interactions | 761 | 10 | 6 | 19454 | 5460 |
HSD17B10,SRC,HPCAL1,BAG3,LXN,RAF1 |
| 3.455e-02 | -3.37 | Flna (filamin, alpha) | protein interactions | 192176 | 10 | 6 | 19454 | 5460 |
FURIN,MAP2K1,YWHAZ,PTEN,CCNB1,CCNF |
| 3.455e-02 | -3.37 | C4orf19 (chromosome 4 open reading frame 19) | protein interactions | 55286 | 10 | 6 | 19454 | 5460 |
STK24,PDCD10,ABITRAM,EIF3E,CEP19,STK26 |
| 3.455e-02 | -3.37 | PPP1R27 (protein phosphatase 1 regulatory subunit 27) | protein interactions | 116729 | 10 | 6 | 19454 | 5460 |
SMCP,GCC1,RPL9,DDIT4L,NTAQ1,PPP1CB |
| 3.455e-02 | -3.37 | S100PBP (S100P binding protein) | protein interactions | 64766 | 10 | 6 | 19454 | 5460 |
KDM1A,COP1,APEX1,PCED1A,PHF21A,PCED1B |
| 3.455e-02 | -3.37 | SBK1 (SH3 domain binding kinase 1) | protein interactions | 388228 | 10 | 6 | 19454 | 5460 |
PPM1G,HNRNPL,YTHDF1,SRPK2,PACSIN3,FTL |
| 3.455e-02 | -3.37 | TRIM40 (tripartite motif containing 40) | protein interactions | 135644 | 10 | 6 | 19454 | 5460 |
IKBKB,RIGI,NLRP3,IFIH1,LGR4,MAVS |
| 3.455e-02 | -3.37 | TUBB8B (tubulin beta 8B) | protein interactions | 260334 | 10 | 6 | 19454 | 5460 |
ICAM1,MEPCE,HEXIM1,TUBB4B,TFCP2,TUBB |
| 3.455e-02 | -3.37 | Mau2 (MAU2 sister chromatid cohesion factor) | protein interactions | 74549 | 10 | 6 | 19454 | 5460 |
GNG12,RPA2,CHCHD3,GNB4,GNB1,GNAI3 |
| 3.455e-02 | -3.37 | ZNF135 (zinc finger protein 135) | protein interactions | 7694 | 10 | 6 | 19454 | 5460 |
ANXA7,GADD45A,SCNM1,CDKN1A,LMO4,RAP1B |
| 3.455e-02 | -3.37 | ZNF569 (zinc finger protein 569) | protein interactions | 148266 | 10 | 6 | 19454 | 5460 |
DDX39A,CBX5,LMNA,RHOU,CUL3,STK24 |
| 3.455e-02 | -3.37 | SPDYA (speedy/RINGO cell cycle regulator family member A) | protein interactions | 245711 | 10 | 6 | 19454 | 5460 |
FBXO7,CDKN1B,CDK5,RIGI,CDK1,CLIP3 |
| 3.455e-02 | -3.37 | IFI44L (interferon induced protein 44 like) | protein interactions | 10964 | 10 | 6 | 19454 | 5460 |
PSMA1,LDHA,MDH1,LHX2,LYZ,CALML5 |
| 3.455e-02 | -3.37 | C6orf136 (chromosome 6 open reading frame 136) | protein interactions | 221545 | 10 | 6 | 19454 | 5460 |
FBXW7,RNF126,RIGI,KIAA0232,MAP1S,CSNK2B |
| 3.455e-02 | -3.37 | FOLH1B (folate hydrolase 1B (pseudogene)) | protein interactions | 219595 | 10 | 6 | 19454 | 5460 |
CCT7,PRPS1,HNRNPL,H3C1,CCT2,TCP1 |
| 3.455e-02 | -3.37 | SLC8A2 (solute carrier family 8 member A2) | protein interactions | 6543 | 10 | 6 | 19454 | 5460 |
GPR35,YWHAZ,GPM6A,RIGI,YWHAB,GPR37 |
| 3.455e-02 | -3.37 | PPIAL4C (peptidylprolyl isomerase A like 4C) | protein interactions | 653598 | 10 | 6 | 19454 | 5460 |
MED17,KRAS,CD151,H1-1,DUSP9,SERPINB9 |
| 3.455e-02 | -3.37 | DHDDS (dehydrodolichyl diphosphate synthase subunit) | protein interactions | 79947 | 10 | 6 | 19454 | 5460 |
HPCA,MAP1LC3B,NUS1,FOXP4,NPC2,KRAS |
| 3.455e-02 | -3.37 | OR5F1 (olfactory receptor family 5 subfamily F member 1) | protein interactions | 338674 | 10 | 6 | 19454 | 5460 |
IRGQ,EFHD2,CCDC25,HMGCS1,GNPNAT1,WDR44 |
| 3.455e-02 | -3.37 | CCDC83 (coiled-coil domain containing 83) | protein interactions | 220047 | 10 | 6 | 19454 | 5460 |
PPID,RBM12,CSK,CHMP2A,TTC33,ASPM |
| 3.455e-02 | -3.37 | MYL7 (myosin light chain 7) | protein interactions | 58498 | 10 | 6 | 19454 | 5460 |
PPM1B,PSORS1C2,MCCD1,UFL1,TOX4,SPPL3 |
| 3.455e-02 | -3.37 | ZNF561 (zinc finger protein 561) | protein interactions | 93134 | 10 | 6 | 19454 | 5460 |
MOV10,AGR2,TEX19,CUL3,PSMC1,STYK1 |
| 3.455e-02 | -3.37 | SLC35A3 (solute carrier family 35 member A3) | protein interactions | 23443 | 10 | 6 | 19454 | 5460 |
HNRNPL,H2BC9,PDE2A,SEC61B,APEX1,CRADD |
| 3.455e-02 | -3.37 | DAW1 (dynein assembly factor with WD repeats 1) | protein interactions | 164781 | 10 | 6 | 19454 | 5460 |
H3C1,H2AC13,RPL26L1,CBX5,SRPK2,SUV39H1 |
| 3.455e-02 | -3.37 | DGKA (diacylglycerol kinase alpha) | protein interactions | 1606 | 10 | 6 | 19454 | 5460 |
DHRS4,SMAD2,SRC,IL21,ORC5,EEF1AKMT3 |
| 3.457e-02 | -3.36 | nuclear body | cellular component | GO:0016604 | 856 | 273 | 19108 | 5553 |
SNAPC2,UHMK1,UQCC2,XPO1,PML,CDK9,PARP11,SUMO3,CSNK2B,RBM27,CGAS,SRSF1,TESK2,PLAGL1,INPPL1,ZBED1,SUMO1,TRIP4,EWSR1,SRPK2,SF3B1,THAP7,H2AX,THOC6,SMC4,SRSF4,AR,DAPK3,CXXC1,VIRMA,ABITRAM,RGS10,SNRPD3,TOPBP1,DDX1,SRSF2,RDM1,ASCC1,PLCB1,RP2,NR4A2,TFIP11,PPP1R8,GEMIN8,NCAPG2,TNKS,HBP1,PRPF18,PIR,TRIM8,NHP2,NUDT9,DDX42,SUMO2,POLDIP3,HSPB6,MAGOH,TP53,PSKH1,SMNDC1,AKAP17A,CBX5,POLR2D,PCGF2,SATB1,SNRPB2,RCHY1,THOC2,HECTD1,TAB1,PHC1,ALKBH5,FAM118B,EIF2D,SNRPA1,PPIH,SMU1,APEX1,PCNA,UBE2I,SMN1,DRG1,RSRC1,LMNA,DDX5,POMP,NONO,NFE2,RADX,LSM10,HIKESHI,PIP5K1A,CNOT7,E4F1,SRSF10,OGG1,DHX9,NXT1,TREML1,TRIM22,TCIM,MYCT1,WRAP53,GTF2H4,HNRNPA2B1,MDC1,FAS,PRPF31,FBXL3,CREBBP,LUC7L3,PIAS1,COP1,BABAM1,ATF4,WTAP,ALYREF,DHX15,TSPAN15,THRAP3,NDUFS3,APBB3,NR0B1,DSN1,ZC3H14,CHTOP,BCL6,RB1,MDM2,ZNF451,PSMB7,CSNK1A1,PHAX,HP1BP3,EIF4E,TMEM179B,IK,BRCA1,EIF4A3,THOC1,SIRT7,TAF5L,RPAIN,COPS4,EIF3E,DKC1,SRSF7,BHLHE40,THAP1,AKAP8L,SOX2,SRSF8,FAM193B,UBN1,MSX2,GFI1,SNAPC3,DDX46,FBXL4,CDK12,PRPF19,TERT,HINFP,BNIP3L,BOLA3,LPXN,ATPAF2,SNRNP70,THOC3,SURF2,DVL2,MEF2C,PPP1R10,SAP18,NUFIP2,DYRK1A,TP53INP1,ZBTB16,PRCC,NT5C3A,PQBP1,RBM15B,COIL,RAPGEF5,DGCR8,PHF7,HEXIM2,SNAPC5,FAM107A,SRP54,VPS72,DDX39A,NR1I2,PRPF4,USP15,SPOP,FYTTD1,PPIG,SRSF12,TRIM27,CDC5L,CWC15,GTF2B,UNC45A,TOPORS,CHAMP1,RNF34,FOXC2,RERE,IL15,ABHD17A,IFI16,KIF2A,NGRN,TP53INP2,NRDE2,EAF2,SQSTM1,RMI2,TERC,CDC40,S100PBP,SCNM1,ZNF473,PPWD1,PTEN,HCFC2,RMI1,HIRA,BECN1,RFXAP,GADD45A,CSNK2A1,BPNT2,UBL5,CBLL1,API5,ZNF174,MTDH,AIPL1,TOLLIP,GTF2H2,ZBTB18,ZMYM2,DDX39B,STK4,CIART,SLU7,CD2BP2,MORF4L1,GEMIN7,RNF113A,SNRNP40,FAM76B,RING1,PSPC1,ADD1,NOP58,NBN,JADE1,SF3A1,SART3,HDAC5,RPA2,MRPL36,CASC3,RETREG1,CDKN1A,ISG20,PPP1CC,OIP5,NAA15,CACNB4 |
| 3.465e-02 | -3.36 | ZMYND8 (zinc finger MYND-type containing 8) | protein interactions | 23613 | 183 | 63 | 19454 | 5460 |
ZCCHC17,E2F6,MACROH2A2,NOTCH2,FAXC,SUPT4H1,KDM1A,FXR2,FBXW7,MBD3,BCL6,CMAS,ARG2,PRKCB,HADHA,SPOP,ZNF687,AR,RBBP4,FBXO22,POLR2B,VIRMA,ESR2,APEX1,RPL22,ZNF330,INTS10,CSNK2B,MACROH2A1,PHF21A,BPIFB1,CBX3,GRAP2,MTA2,MTA3,CSNK1E,SOX2,H2AX,RPL15,CTNNBL1,H3C1,RBBP7,ZNF592,KRAS,KCTD17,CDK2AP2,SSRP1,RERE,RPS24,DHX9,H2AC4,LRRC8B,BRD3,ZCCHC10,CSNK2A1,TOP1,SUMO2,RPS27L,HMG20A,ZBTB2,H2AZ1,TRAF3IP3,GATAD1 |
| 3.475e-02 | -3.36 | Formation of HIV elongation complex in the absence of HIV Tat | REACTOME pathways | R-HSA-167152 | 52 | 23 | 10285 | 3229 |
TCEA1,GTF2H2,POLR2D,POLR2L,GTF2H5,ELOC,POLR2G,SUPT4H1,GTF2F2,POLR2F,SUPT5H,POLR2B,NCBP2,MNAT1,CDK7,GTF2F1,POLR2I,CCNH,POLR2C,GTF2H4,ERCC3,SSRP1,CDK9 |
| 3.480e-02 | -3.36 | Piwi | smart domains | SM00950 | 8 | 5 | 9717 | 2575 |
PIWIL1,PIWIL2,PIWIL4,AGO1,PIWIL3 |
| 3.481e-02 | -3.36 | positive regulation of lymphocyte differentiation | biological process | GO:0045621 | 135 | 50 | 18204 | 5365 |
IL7,BAD,CBFB,CD80,RAG1,IL23A,IL15RA,WNT10B,SMARCB1,IL15,IL2RA,RHOH,LILRB4,MIR21,CCL19,IL2,TGFBR2,CD46,IL4,ZBTB16,NLRP3,RUNX1,SOCS5,SMARCD3,XBP1,TOX,IL2RG,CD86,TESPA1,MMP14,IL12B,IL10,IFNG,VSIR,ACTL6B,ACTB,EP300,KLHL25,DUSP10,SMARCE1,BTN2A2,BCL6,FOXP3,IL18,PNP,CD83,SYK,NKAP,SASH3,ACTL6A |
| 3.481e-02 | -3.36 | organic acid transmembrane transport | biological process | GO:1903825 | 135 | 50 | 18204 | 5365 |
SLC7A9,SLC7A1,KCNJ10,ABCB1,UCP2,ABCC5,SLC43A2,SLC7A11,SLC2A1,SLC13A5,SLC25A1,CPT1B,SLC23A2,CPT2,SLC1A2,SLC1A1,SLC6A7,SLC25A21,SLC7A8,SLC5A6,LRRC8A,SLC1A3,SLC6A11,LRRC8B,SFXN2,GRM1,MPC1,SLC35D1,SFXN1,SLC25A26,SLC17A5,CLN8,SLC38A9,LRRC8D,SLC25A11,CD36,SLC38A2,SLC38A1,SLC25A10,SLC25A12,SLC38A3,SLC25A32,TSPO2,SLC25A20,SLC6A6,ARL6IP5,PSEN1,LRRC8C,SLC6A8,SLC16A1 |
| 3.482e-02 | -3.36 | SIRPA (signal regulatory protein alpha) | protein interactions | 140885 | 85 | 32 | 19454 | 5460 |
ILK,RHOB,PPM1B,SHC1,TRIM23,CD81,AKT1,CALR,PTPN11,HSP90AB1,JAK2,STAT1,CD47,PHYH,PSMC5,TRIM27,HRAS,PSMA6,HSP90B1,DDX39A,MX1,FTH1,TPT1,ARF4,HSPA5,IL1RAP,KRAS,EIF5B,GNL1,HSPA8,IGF1R,ARHGEF6 |
| 3.482e-02 | -3.36 | ING3 (inhibitor of growth family member 3) | protein interactions | 54556 | 85 | 32 | 19454 | 5460 |
LDLR,CSNK2B,UBE2S,RSRC1,VPS72,H2AZ1,S100A6,SNRPA1,NKAP,NR1H2,MEAF6,TRIM54,MORF4L1,SIVA1,MYC,HNF1B,BAZ1B,KPNA1,RUVBL2,RPA3,HSPA5,FBXO25,RUVBL1,ING1,MAX,ACTL6A,TFIP11,PLAC1,H2BC1,ZCCHC17,DMAP1,RPA2 |
| 3.482e-02 | -3.36 | pyrimidine-containing compound biosynthetic process | biological process | GO:0072528 | 41 | 18 | 18204 | 5365 |
SHMT1,NME1,UCKL1,UCK1,NME2,AK5,NME4,THTPA,SLC19A3,UPRT,SLC19A2,PRPS1,TYMS,DCK,DTYMK,UMPS,CMPK1,UCK2 |
| 3.482e-02 | -3.36 | thioester biosynthetic process | biological process | GO:0035384 | 41 | 18 | 18204 | 5365 |
HACD2,ELOVL6,ACSS2,TECR,DLAT,MMUT,ELOVL7,PPT1,HACD1,ELOVL3,PDHA1,ACSL4,ACAT1,SLC25A1,ACACA,ELOVL1,PDHB,ELOVL4 |
| 3.482e-02 | -3.36 | regulation of autophagy of mitochondrion | biological process | GO:1903146 | 41 | 18 | 18204 | 5365 |
FKBP8,TP53,VDAC1,TSPO,HTRA2,FBXO7,STUB1,BNIP3L,PARL,SLC25A5,USP30,RNF41,CTTN,SLC25A4,HAX1,FBXW7,GSK3A,HDAC6 |
| 3.482e-02 | -3.36 | acyl-CoA biosynthetic process | biological process | GO:0071616 | 41 | 18 | 18204 | 5365 |
MMUT,DLAT,ELOVL6,HACD2,ACSS2,TECR,ELOVL7,PPT1,HACD1,ELOVL3,PDHA1,ACSL4,ACAT1,ELOVL1,ACACA,SLC25A1,ELOVL4,PDHB |
| 3.485e-02 | -3.36 | BIRC5 (baculoviral IAP repeat containing 5) | protein interactions | 332 | 113 | 41 | 19454 | 5460 |
PYCARD,MED22,HDAC6,DEPDC1B,XPO1,COPS5,CCDC85B,UFD1,PPP1CC,MED21,MED10,MED29,BECN1,HSP90AA1,STAMBPL1,MED4,RIT1,AIP,RAN,RB1,DCK,MAP3K3,MED17,CBX5,USP38,ZBTB2,RAF1,E2F4,CDK4,MED30,H2AX,FBXL7,CDK1,CHMP4C,MED31,BIRC5,BIRC2,KRAS,STAU1,FBXW7,MDC1 |
| 3.485e-02 | -3.36 | UBR2 (ubiquitin protein ligase E3 component n-recognin 2) | protein interactions | 23304 | 113 | 41 | 19454 | 5460 |
FOXJ3,METTL15,TIRAP,FAF2,UBXN2B,SPC24,NUDT16,SOD2,PDP2,NDUFS3,UBE2B,PAK5,METTL2A,MRPS11,ATF3,NOG,FAF1,UBE2A,DUSP26,HNRNPA1,NTAQ1,CFC1,CRHBP,MYC,IGFBP4,UBE2H,NRP1,CBL,BRCA1,TEX19,RHOB,SPCS3,PLEKHO2,GCFC2,PARL,VIRMA,EGLN3,CELA3B,SNX18,MRPL50,HNRNPL |
| 3.487e-02 | -3.36 | regulation of lymphocyte mediated immunity | biological process | GO:0002706 | 187 | 67 | 18204 | 5365 |
CYRIB,KLRD1,IFNA2,LILRB4,CD81,CD46,IL2,CCR2,NLRP3,TRAF6,IL4,CD1C,NDFIP1,CD1B,SH2D1A,TNFSF13,TNFRSF1B,IL20RB,CLEC12B,FCGR1A,EXOSC3,IL23A,LTA,CD80,CD28,B2M,SERPINB9,STX7,MAD2L2,HMCES,IFNB1,CD1A,NECTIN2,AGER,CD226,LEP,NCR3,MICB,FCGR2B,STAT6,BCL6,HSPD1,HFE,FOXP3,IL12A,LILRB1,HSPA8,IL1B,CD40,CD1D,HMGB1,SASH3,IL18,TFRC,KLRC2,KMT5B,IL6,SHLD1,RSAD2,TRAF2,IL21,CD1E,XCL1,DUSP22,IL10,IL12B,TNF |
| 3.487e-02 | -3.36 | positive regulation of RNA biosynthetic process | biological process | GO:1902680 | 1670 | 525 | 18204 | 5365 |
NFYB,ESR2,HEXB,GTF2I,IER2,EZH1,PRIM2,RFXAP,LHX2,LUM,EPO,ZNF668,NR4A2,TRIM44,TRIM15,CNOT7,MYRF,IKBKB,TGFB1I1,EGR1,PPARG,SP1,EPCAM,CCNA2,TRIM52,RNF20,RHOG,FOXJ3,ZNHIT1,PGR,RNF187,JUP,SOST,VPS72,MITF,ITGA6,NCBP2,UBP1,TAF7,ACTL6B,TP53,PAX9,ZBED3,KLF4,DDIT3,TRIM27,TLR4,ARF4,TFPT,JADE1,DNAJC2,HELT,ZNF574,ZNF473,TRIP4,P2RY1,VGLL2,RAP2C,CSRNP3,ACSS2,SIX5,FBXW11,ILK,OGG1,RB1,CITED1,MED4,ZNF593,CXCL10,SUPT5H,NFYA,USP16,NDN,CDK9,IRF4,FOXC2,NEUROG2,PLSCR1,TFDP2,ZBED4,BRD3,LDB1,ACVR1,CEBPG,NLRP3,MSX1,ING1,PHB1,RUVBL1,RBBP7,LBH,NAA15,CRLF3,TNF,HMGA1,ACTB,DDRGK1,RBPJ,SF3B1,IL10,H2AZ1,YAF2,RAF1,ARMCX3,CX3CL1,GABPA,HINFP,S100A10,MED11,GTF2A2,BATF,HRAS,ZNF304,FGF7,HMGB1,TOP2B,SSBP4,PLAC8,INO80C,ZNF770,CD28,CBFB,TADA1,PIM2,RUVBL2,MSTN,ING2,SUPT7L,MEF2C,IFNB1,MEPCE,GPBP1L1,MEAF6,KANSL3,MAVS,TNKS,ZBTB17,ZGLP1,NKRF,CD81,PSEN1,EGR2,CD4,HSPA5,IRF9,RUNX1,MDC1,BUD31,TAF5L,ILF2,BRCA1,SLC38A3,IL4,MYD88,SMAD2,TAF2,SFRP1,CREB1,RTRAF,MYC,MARS1,AGO1,NUPR1,CASK,RORB,PELP1,SSBP2,DLX1,WWP2,MOSPD1,TLR3,NFIL3,MAP3K12,MED21,IRF3,HEY2,BARX2,GTF2F2,RFX4,SMAD5,KLF12,SETD7,TNFSF8,HNF1B,PSRC1,YWHAH,RPS6KA4,OSR2,LILRB1,APLN,INPP5K,BCL10,IRF8,SHC1,PRMT2,PRKCB,MAP2K1,CTBP1,HDAC5,PAGR1,FOSL2,SETD3,ANKRD49,NUCKS1,COPS5,ZBED1,IRF7,TLR7,SMAD1,EDF1,IL5,RGMB,RIT2,KDM1A,NR1I2,ACTN4,CDC5L,TOPORS,RBM23,CNOT6,SF3B5,PICALM,MAFG,LITAF,CDK7,TADA3,NFE2,SUB1,TRIM22,HOXC4,BAZ1B,STAT2,SOX9,AIP,MTF1,RERE,FGF10,SCAND1,NCK1,TRIM8,RPRD1B,IRF6,ZBTB38,TF,RASL11A,NOTCH2,IL1A,MAP2K3,TGFB2,CDH13,STAT6,ZNF345,ZBTB18,ADRB2,HCFC2,GREM1,CREBBP,PROX1,MBD3,HAND2,PRDM4,MTDH,NFKBIB,WASL,SOX2,MSL2,IRF2,TRIM37,SPP1,DYRK1A,HOXB1,DHX9,ABHD14B,TFE3,VEGFA,MTA2,IL23A,BMPR2,CCAR1,NFE2L2,SOX3,SMAD9,MECP2,SMARCB1,BCL9,FGF23,BMPR1A,LMO3,FZD4,NIBAN2,ELK4,IFI16,DEK,SOX14,ZNF319,ACTR2,CAMK1,RFXANK,PIK3R2,SETD4,KLF1,PIK3R1,NR2E1,OSM,UTP15,AFAP1L2,IRF1,PQBP1,MEF2A,SUPT4H1,STK16,ETV6,IL17F,TAF10,MED17,APEX1,ZNF175,HNRNPK,SQSTM1,ATF4,TRIM21,TFEB,IL18,ZNF609,SMARCA5,ELK3,PIH1D1,TERT,NFKB1,SERTAD3,HLF,SUPT3H,CHCHD2,PSMC5,FOS,HCLS1,TFCP2,IRF2BPL,BMPR1B,WBP2,NUP62,POU1F1,ARL2BP,PIAS1,RNF10,AKAP8L,RNF40,STAT5A,PLAGL1,TBK1,CD38,MRPL12,ZNF287,NDP,TRAF6,TLR2,MED9,UBE2L3,TAF9,TRIM32,HNRNPD,WNT2,BIRC2,YES1,SERTAD1,MED23,TRIM62,PCBD1,NIF3L1,CSRNP1,SMAD3,TCEA1,CRTC2,SGF29,TESC,PKNOX1,NOG,EAF2,ATF3,NME2,FOXA3,NKX3-1,MED22,TRIM5,CREB3,NR1I3,PITHD1,CD40,MED30,KLF10,MED10,CD80,UCN,GABPB1,TCF21,POU5F1,GTF2A1,FOXD3,TP53INP2,MED27,MED29,PAX6,RIGI,SSBP3,LYAR,MAD2L2,SMYD3,ELK1,WNT10B,ECD,CDC73,MEF2B,ZNF507,HDAC3,MLLT6,SMARCD3,DNM2,PLCB1,TLR9,CREBL2,RGCC,ZBTB16,ZNF24,MYBL2,ID4,RFX5,IL6,GTF2F1,EFCAB7,TP53INP1,SOX21,ZFP64,CD86,ZNF267,ZNF513,THRAP3,UBE3A,RNF14,ELF1,RNASEL,LDB2,E2F4,NEUROD2,ZNF263,MTA3,HAX1,CXXC1,RXRG,SMARCE1,PPARA,HAS3,JUN,ACTL6A,PPP1R12A,PRL,OTX2,JUNB,DMAP1,CD274,FOXP3,GSK3A,KPNA6,DVL2,CDK5RAP3,ATF1,RGMA,LMO2,TAF11,JAK2,E4F1,MORF4L1,MED31,LRP6,STAT1,FGF1,NR1H2,CAND1,IL2,PSMC3,CYTL1,CDK12,SS18,HNRNPAB,RRN3,TRIM24,AR,MET,LMO4,XBP1,CREBZF,AATF,PID1,MLLT11,MAX,HYAL2,BACH1,VDR,RBBP4,CTNNB1,TOX,NEUROD6,TEF,CREB3L4,MT3,ENY2,EP300,SNX5,NFKBIA,IGF1,KARS1,SIRT7,WDR77,NAA16,FUBP3,INO80E,SMAD4,SERTAD2,PPP3CA,WNT7A,CEBPE,UBE2V1,TGFB3,IL1B,DYRK1B,AKT1 |
| 3.494e-02 | -3.35 | regulation of mRNA processing | biological process | GO:0050684 | 132 | 49 | 18204 | 5365 |
RBFOX3,ARB2A,RBM23,CDC73,SNRNP70,RBM3,RBM15B,TIA1,CIRBP,CPEB1,TRA2A,CELF6,SRSF4,SMU1,UPF3B,SRSF10,TRA2B,PRPF19,RBFOX2,CDK9,RBM42,RBM5,SRSF7,HNRNPK,SRSF12,NOVA1,HNRNPA2B1,SF3B4,PRDX6,PRMT5,DYRK1A,HSPA8,HNRNPL,DHX9,SAP18,MAGOHB,NCBP2,DDX5,AHCYL1,HNRNPA1,SRSF2,WDR77,PCBP4,WTAP,MAGOH,RBM7,SRPK2,HMX2,THRAP3 |
| 3.495e-02 | -3.35 | ephrin receptor binding | molecular function | GO:0046875 | 27 | 13 | 18094 | 5411 |
NCK1,EPHA4,SIPA1L1,SRC,SHC1,CDK5R1,EFNB1,CBL,PTPN1,EFNA3,PIK3CG,EFNA5,SDCBP |
| 3.500e-02 | -3.35 | SUMO is transferred from E1 to E2 (UBE2I, UBC9) | REACTOME pathways | R-HSA-3065678 | 7 | 5 | 10285 | 3229 |
SUMO3,UBE2I,RWDD3,SUMO2,SUMO1 |
| 3.506e-02 | -3.35 | positive regulation of lymphocyte mediated immunity | biological process | GO:0002708 | 129 | 48 | 18204 | 5365 |
TNFSF13,SH2D1A,CD1B,CD1C,IL4,TRAF6,NLRP3,IL2,CD81,KLRD1,CYRIB,HMCES,MAD2L2,STX7,B2M,CD28,LTA,IL23A,EXOSC3,FCGR1A,IL18,SASH3,CD1D,CD40,IL1B,HSPA8,FOXP3,IL12A,HFE,HSPD1,STAT6,MICB,NCR3,CD226,NECTIN2,CD1A,TNF,IL12B,XCL1,CD1E,TRAF2,IL21,RSAD2,SHLD1,IL6,KMT5B,KLRC2,TFRC |
| 3.508e-02 | -3.35 | regulation of natural killer cell proliferation | biological process | GO:0032817 | 12 | 7 | 18204 | 5365 |
IL23A,JAK2,PTPN22,IL18,IL15,IL12B,LEP |
| 3.508e-02 | -3.35 | regulation of transforming growth factor beta1 production | biological process | GO:0032908 | 12 | 7 | 18204 | 5365 |
FOXP3,CX3CL1,ATP6AP2,FURIN,CD2AP,TYROBP,LUM |
| 3.508e-02 | -3.35 | pyrimidine ribonucleoside monophosphate biosynthetic process | biological process | GO:0009174 | 12 | 7 | 18204 | 5365 |
UCK1,DCK,UCKL1,UPRT,UCK2,CMPK1,UMPS |
| 3.508e-02 | -3.35 | proteasome assembly | biological process | GO:0043248 | 12 | 7 | 18204 | 5365 |
POMP,ADRM1,OTUD6B,PSMG3,PSMD10,PSMG4,PSMG2 |
| 3.508e-02 | -3.35 | negative regulation of acute inflammatory response | biological process | GO:0002674 | 12 | 7 | 18204 | 5365 |
SELENOS,NPY5R,ADORA1,NLRP3,IL20RB,GSTP1,FCGR2B |
| 3.508e-02 | -3.35 | regulation of establishment of protein localization to chromosome | biological process | GO:0070202 | 12 | 7 | 18204 | 5365 |
DKC1,CCT7,TCP1,CCT2,CCT8,CCT5,WRAP53 |
| 3.508e-02 | -3.35 | neurotransmitter-gated ion channel clustering | biological process | GO:0072578 | 12 | 7 | 18204 | 5365 |
GPHN,NLGN2,LHFPL4,GLRB,NLGN1,DLG4,CHRDL1 |
| 3.508e-02 | -3.35 | regulation of metalloendopeptidase activity | biological process | GO:1904683 | 12 | 7 | 18204 | 5365 |
MIR205,TIMP3,MIR29C,MIR17,MIR152,MIR24-1,MIR21 |
| 3.508e-02 | -3.35 | negative regulation of CD4-positive, alpha-beta T cell proliferation | biological process | GO:2000562 | 12 | 7 | 18204 | 5365 |
ARG2,TWSG1,VSIR,FOXP3,CD274,NDFIP1,XCL1 |
| 3.508e-02 | -3.35 | nucleoside salvage | biological process | GO:0043174 | 12 | 7 | 18204 | 5365 |
MTAP,DCTD,PNP,QNG1,DNPH1,UCKL1,ADK |
| 3.508e-02 | -3.35 | vacuole fusion | biological process | GO:0097576 | 12 | 7 | 18204 | 5365 |
CHMP4C,CHMP2B,CHMP1A,CHMP5,CHMP2A,CHMP1B,VPS16 |
| 3.508e-02 | -3.35 | positive regulation of catecholamine secretion | biological process | GO:0033605 | 12 | 7 | 18204 | 5365 |
OXTR,STX1A,CHRNB2,CARTPT,CXCL12,KCNB1,OPRK1 |
| 3.508e-02 | -3.35 | negative regulation of neuroblast proliferation | biological process | GO:0007406 | 12 | 7 | 18204 | 5365 |
CTNNA1,PROX1,PTN,TP53,BTG2,MIR137,PAX6 |
| 3.508e-02 | -3.35 | cytidine to uridine editing | biological process | GO:0016554 | 12 | 7 | 18204 | 5365 |
APOBEC3H,APOBEC3D,APOBEC3G,APOBEC3B,APOBEC3F,APOBEC3A,APOBEC3C |
| 3.508e-02 | -3.35 | positive regulation of keratinocyte migration | biological process | GO:0051549 | 12 | 7 | 18204 | 5365 |
MMP9,HBEGF,FGF10,MAPRE2,FGF7,ARF6,IQSEC1 |
| 3.508e-02 | -3.35 | cellular response to nitrogen starvation | biological process | GO:0006995 | 12 | 7 | 18204 | 5365 |
MAP1LC3A,GABARAP,BECN1,ATG7,GABARAPL2,GABARAPL1,MAP1LC3B |
| 3.508e-02 | -3.35 | negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological process | GO:1900152 | 12 | 7 | 18204 | 5365 |
DHX9,TENT4A,PAIP1,SYNCRIP,PABPC1,IGF2BP1,HNRNPD |
| 3.508e-02 | -3.35 | positive regulation of protein localization to chromosome, telomeric region | biological process | GO:1904816 | 12 | 7 | 18204 | 5365 |
CCT7,CCT8,WRAP53,DKC1,CCT2,TCP1,CCT5 |
| 3.508e-02 | -3.35 | ADP transport | biological process | GO:0015866 | 12 | 7 | 18204 | 5365 |
SLC25A23,SLC25A24,SLC25A4,SLC25A5,SLC25A31,SLC25A17,SLC25A42 |
| 3.508e-02 | -3.35 | water-soluble vitamin biosynthetic process | biological process | GO:0042364 | 12 | 7 | 18204 | 5365 |
PNPO,AKR1B1,AKR1A1,THTPA,SLC19A3,RGN,SLC19A2 |
| 3.508e-02 | -3.35 | positive regulation of vascular associated smooth muscle cell apoptotic process | biological process | GO:1905461 | 12 | 7 | 18204 | 5365 |
SOD2,MIR24-1,MIR140,ATF4,PPARG,MIR1-1,PDCD4 |
| 3.508e-02 | -3.35 | small nucleolar ribonucleoprotein complex assembly | biological process | GO:0000491 | 12 | 7 | 18204 | 5365 |
RUVBL1,RUVBL2,ZNHIT6,NOPCHAP1,TAF9,ZNHIT3,PIH1D1 |
| 3.508e-02 | -3.35 | regulation of vitamin metabolic process | biological process | GO:0030656 | 12 | 7 | 18204 | 5365 |
IFNG,CYP27B1,GFI1,TNF,NFKB1,RDH10,SNAI2 |
| 3.508e-02 | -3.35 | mitochondrial electron transport, ubiquinol to cytochrome c | biological process | GO:0006122 | 12 | 7 | 18204 | 5365 |
UQCRQ,UQCRC2,UQCR11,UQCC3,UQCRH,CYC1,UQCRC1 |
| 3.508e-02 | -3.35 | cellular response to antibiotic | biological process | GO:0071236 | 12 | 7 | 18204 | 5365 |
EZH2,CDKN1B,MDM2,TP53,RPL23,CRIP1,MEF2C |
| 3.508e-02 | -3.35 | cellular response to nitrogen levels | biological process | GO:0043562 | 12 | 7 | 18204 | 5365 |
BECN1,ATG7,GABARAP,GABARAPL2,GABARAPL1,MAP1LC3A,MAP1LC3B |
| 3.508e-02 | -3.35 | negative regulation of receptor binding | biological process | GO:1900121 | 12 | 7 | 18204 | 5365 |
MIR148A,HFE,PCSK9,IL10,ADIPOQ,NOG,B2M |
| 3.514e-02 | -3.35 | regulation of striated muscle contraction | biological process | GO:0006942 | 99 | 38 | 18204 | 5365 |
EHD3,CLIC2,CAV1,STC1,MIR200C,FGF13,SRI,CAV3,MIR448,SUMO1,ATP1A1,CHGA,MIR1-1,KBTBD13,UCN,FKBP1B,MIR30E,RGS2,GSTO1,JUP,GSTM2,ADRA1A,ADORA1,TMEM38B,RANGRF,PLN,DMPK,KCNJ2,DLG1,PDE4B,ATP1A2,SLC8A1,PIK3CG,ASB3,HSP90AA1,TNNI1,ATP1B1,TNNI3K |
| 3.515e-02 | -3.35 | DZIP1 (DAZ interacting zinc finger protein 1) | protein interactions | 22873 | 40 | 17 | 19454 | 5460 |
YWHAZ,TIAM1,YWHAB,PPP2R5A,ZCCHC10,TP53,DNAJC5,YWHAG,YWHAH,PPP1R18,CAMK2G,CAV1,FLOT1,RAB35,OPTN,NTRK2,GJA1 |
| 3.515e-02 | -3.35 | GAP43 (growth associated protein 43) | protein interactions | 2596 | 40 | 17 | 19454 | 5460 |
ELAVL4,OAT,DHRS3,FBXO34,CCR1,MED21,GDE1,CSNK2A1,CENPM,LDHB,PCK2,MYC,SPTAN1,CERS2,TMEM185A,BIRC2,PRKCB |
| 3.515e-02 | -3.35 | KLHL18 (kelch like family member 18) | protein interactions | 23276 | 40 | 17 | 19454 | 5460 |
EIF4EBP3,FUBP3,COPS2,DCUN1D1,EEF1G,ATP6V1G1,CEP97,VIRMA,COPS4,PIK3R1,CUL3,COPS5,NUDCD3,CFTR,UBE2M,RTF2,RNF181 |
| 3.515e-02 | -3.35 | DUSP8 (dual specificity phosphatase 8) | protein interactions | 1850 | 40 | 17 | 19454 | 5460 |
NDUFAF3,VPS26A,RAB5C,ANKMY2,ARPC3,CAPZA2,PTRH2,PSMD10,CBX3,FBXO11,DUSP6,NDUFAF4,PTGES3,PPP5C,UBE2L3,NDUFS8,SPPL3 |
| 3.515e-02 | -3.35 | H3C12 (H3 clustered histone 12) | protein interactions | 8356 | 40 | 17 | 19454 | 5460 |
PRKACB,UBR7,MTA2,MACROH2A2,PDHA1,MACROH2A1,TRIM24,HIRA,PARP2,CBX5,RPS27A,PTP4A3,PHF1,SSRP1,RBBP7,ASF1A,RBBP4 |
| 3.515e-02 | -3.35 | CXCL14 (C-X-C motif chemokine ligand 14) | protein interactions | 9547 | 40 | 17 | 19454 | 5460 |
CCL21,TRIM23,LMNA,RPRD1B,CCL28,CCL11,GPR85,CCL5,CXCL12,XCL1,CXCL10,CXCL9,CXCL11,CTNNBL1,CHCHD2,DCTN3,DCTN6 |
| 3.515e-02 | -3.35 | BMF (Bcl2 modifying factor) | protein interactions | 90427 | 40 | 17 | 19454 | 5460 |
YTHDF2,BAK1,BAG3,MGAT5B,SHC3,BCL2L1,TFIP11,BAX,BAD,GPSM3,MCL1,CXCL9,DYNLL1,TRIM54,BNIP3L,BCL2A1,VIRMA |
| 3.515e-02 | -3.35 | RBM41 (RNA binding motif protein 41) | protein interactions | 55285 | 40 | 17 | 19454 | 5460 |
COIL,MAD2L1,TRAF1,TRIM54,SNRNP40,HNRNPK,TRIM27,PNMA1,RINT1,CCHCR1,UBE2H,BICD2,DISC1,TRAF2,RALYL,CCDC85B,HNRNPC |
| 3.515e-02 | -3.35 | DMPK (DM1 protein kinase) | protein interactions | 1760 | 40 | 17 | 19454 | 5460 |
RAF1,LGR4,ANXA7,PLN,CDC73,SP1,PDCD10,TST,HSP90AA1,BCKDK,PPP1R12A,BAP1,HSPB2,STK38,RPS10,GABARAP,SMN1 |
| 3.517e-02 | -3.35 | mandible | COSMIC cancer mutations | mandible | 28 | 13 | 16828 | 4835 |
KRAS,HRAS,IDH1,CDC73,EWSR1,SUFU,TP53,CTNNB1,IDH2,AKT1,PIK3CA,SMARCB1,CDH11 |
| 3.523e-02 | -3.35 | human chr10q21.3 | chromosome location | human chr10q21.3 | 25 | 10 | 26134 | 5823 |
ADO,HNRNPH3,CCAR1,LRRTM3,EGR2,MIR1296,HERC4,NRBF2,PBLD,REEP3 |
| 3.527e-02 | -3.34 | GPBP1L1 (GC-rich promoter binding protein 1 like 1) | protein interactions | 60313 | 82 | 31 | 19454 | 5460 |
YWHAB,AP2A1,UHMK1,PIP4K2C,ECD,YWHAZ,DCAF5,UTP6,YWHAH,XPO1,YWHAG,CNOT8,CNOT2,EGLN3,SNRNP40,PLEKHF2,RPS20,AP2M1,SYT2,METAP2,AP2S1,QRSL1,TNRC6C,EIF3E,CNOT6L,FGF12,TSSC4,CNOT7,EWSR1,GARRE1,FADS2 |
| 3.527e-02 | -3.34 | SLC20A1 (solute carrier family 20 member 1) | protein interactions | 6574 | 82 | 31 | 19454 | 5460 |
SYP,BCL10,RHOG,ICAM2,DNAJC5,LAMP3,ARMC6,NDFIP1,CX3CL1,ARF6,RAMP3,SLC1A1,SYNGR1,CTDSP1,IZUMO1,PALS2,UGCG,SLC20A2,TGFBR2,ARL5B,KRAS,TSPAN5,RNF11,CD83,TSPAN15,LRP10,RHOU,BMPR1A,LIN7C,VIPR1,HAPSTR1 |
| 3.527e-02 | -3.34 | CYP2S1 (cytochrome P450 family 2 subfamily S member 1) | protein interactions | 29785 | 82 | 31 | 19454 | 5460 |
EPHA2,ATP1B3,SLC2A1,TSPAN10,ICAM2,ADIPOR2,TXNRD2,GPBAR1,LAMP2,SRC,B4GAT1,EFNA5,APLNR,RAMP3,YES1,CDCA3,STARD3NL,HRAS,CSNK1G3,PRKCA,FEM1A,AQP3,PALS2,MGARP,TPRA1,GNB4,RGS19,TNFSF8,RAP2A,VIPR1,CXCR4 |
| 3.527e-02 | -3.34 | EPB41L4B (erythrocyte membrane protein band 4.1 like 4B) | protein interactions | 54566 | 82 | 31 | 19454 | 5460 |
RPS10,HNRNPL,ARF6,SRPK2,SURF6,PPIA,SRSF1,HRAS,RAB35,PRKRA,GJA1,H1-1,RPL7A,ZCCHC10,DDRGK1,RPL4,STAU1,UFL1,DGCR8,KRAS,NPM3,CXXC1,RPL31,BIRC2,MRFAP1,HSPA8,RPL3,PCLAF,RPLP0,TRAF2,CDC42 |
| 3.527e-02 | -3.34 | MSMO1 (methylsterol monooxygenase 1) | protein interactions | 6307 | 82 | 31 | 19454 | 5460 |
LPAR1,DNAJC30,HSCB,TSPAN15,ATP5PF,DDR1,YIF1A,VIPR1,BSCL2,LPAR2,ERG28,MMP14,GPR35,AQP3,SERPINA5,CCDC47,MGARP,DDX39A,SOX2,APLNR,ILVBL,CHRM5,S1PR4,LDLR,SYNGR1,RETREG3,TMEM11,P2RY1,CYP4F22,DDRGK1,ARL6IP6 |
| 3.527e-02 | -3.34 | ADCK2 (aarF domain containing kinase 2) | protein interactions | 90956 | 82 | 31 | 19454 | 5460 |
SFXN1,MTDH,CLPB,RNF5,FKBP8,IMMP2L,MRPL22,SEC22B,ATP5PB,APOO,TMEM165,SLC4A8,COX4I1,KCNA2,COQ8A,STUB1,SEC61A1,MARCHF4,PARL,ILVBL,CLRN2,STOML2,SEC61A2,MYC,ST13,ESYT1,HTRA2,HAX1,LRRC8B,ATP1A1,DNAJC7 |
| 3.527e-02 | -3.34 | RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase) | protein interactions | 117584 | 82 | 31 | 19454 | 5460 |
UBE2D1,SHC1,MYO6,VCPIP1,USP13,CUL3,VTI1B,ARF6,RAB14,MDM2,UBE2V2,USP5,RAB11B,OPTN,STUB1,UBE2N,UBE2G2,EFCAB7,VIPAS39,TP53,EHD1,UQCRC1,UBE2D3,VAMP8,STX7,TUSC2,STX8,EHD4,RAB13,MYO1B,RNF34 |
| 3.527e-02 | -3.34 | PIP4K2B (phosphatidylinositol-5-phosphate 4-kinase type 2 beta) | protein interactions | 8396 | 82 | 31 | 19454 | 5460 |
CLK1,TRIM63,AHCYL1,SKP1,ATG4C,CDCA7L,ATG16L1,MAX,TULP3,ZNF428,RPRD1B,TNFAIP8L1,CSNK1A1L,CDK1,CSNK1A1,DYRK2,GPBP1L1,ZRANB2,PSMB1,CEP19,EDEM1,ZCCHC10,CSNK2A1,PIP4K2C,DDX23,SPOP,UBE2H,BRD3,STK11,MED4,CDK12 |
| 3.527e-02 | -3.34 | SUPT20H (SPT20 homolog, SAGA complex component) | protein interactions | 55578 | 82 | 31 | 19454 | 5460 |
SF3B5,PLAC1,SUPT7L,TAF10,MED23,SUPT3H,WDR37,RIGI,NF2,H3C1,SGF29,DR1,RPA3,PML,TAF9,KPNA1,BRD3,TADA1,AQP2,TADA3,MYC,PDIA3,TAF5L,ATG9A,ENY2,MAD2L1,DYRK1A,FBXO22,PRNP,RPLP2,ELK3 |
| 3.532e-02 | -3.34 | regulation of nervous system process | biological process | GO:0031644 | 120 | 45 | 18204 | 5365 |
FIG4,CTSC,ROCK2,FABP5,NLGN1,HCRT,MYRF,GLRA1,TMEM100,PTEN,TNF,DLGAP4,CHRNA7,GPR171,IGSF11,GPR35,EIF4A3,TMEM108,CCN3,STX1A,NLGN2,ADORA1,TNR,DAG1,CCL3,MTMR2,WNT7A,GHRL,TNFRSF1B,DMPK,WASF3,DLG4,ADRB2,ITGA2,FGF12,EGR2,MIR30B,CARTPT,CBLN1,RNF10,TPPP,DICER1,TBC1D24,GRM1,NETO1 |
| 3.532e-02 | -3.34 | heterochromatin formation | biological process | GO:0031507 | 120 | 45 | 18204 | 5365 |
CBX3,H2AC4,PCGF3,SMARCA5,BRCA1,BCL6,H2AC1,SUV39H1,PIWIL4,MACROH2A2,NRDE2,H2AB1,HMGB1,LMNA,HELLS,PPM1D,ARB2A,H2AC13,DDX4,POLE3,MBD3,H2AC6,H2AZ2,PIWIL2,LMNB1,EED,RBM15B,H2AJ,MACROH2A1,MAEL,MECP2,H2AZ1,RLIM,H2AC25,SIN3A,SMCHD1,EZH2,RB1,BAHD1,EZH1,H2AC7,LRIF1,CBX5,H2AX,PIWIL1 |
| 3.534e-02 | -3.34 | Dopamine Activation of Neurological Reward System | SMPDB pathways | SMP0000308 | 6 | 5 | 1369 | 531 |
GNB1,GNG12,ADCY2,PRKACB,DRD1 |
| 3.540e-02 | -3.34 | regulation of mRNA splicing, via spliceosome | biological process | GO:0048024 | 111 | 42 | 18204 | 5365 |
RBM15B,PRDX6,PRMT5,RBM3,SF3B4,SNRNP70,HNRNPA2B1,SRSF12,NOVA1,ARB2A,HNRNPK,RBM23,RBFOX3,SRSF7,TRA2A,CIRBP,SAP18,HNRNPL,HSPA8,TIA1,DYRK1A,TRA2B,DDX5,SRSF10,UPF3B,SRSF4,CELF6,SMU1,THRAP3,RBM7,SRPK2,HMX2,MAGOH,WTAP,RBM5,WDR77,PCBP4,RBFOX2,RBM42,SRSF2,PRPF19,HNRNPA1 |
| 3.540e-02 | -3.34 | negative regulation of binding | biological process | GO:0051100 | 111 | 42 | 18204 | 5365 |
SUMO1,ROCK1,BAX,CSNK1E,GTF2F1,B2M,SUMO3,TNKS,MDFI,IL10,PCSK9,CDKN1A,KDM1A,IFIT2,MAD2L2,ACTB,JAK2,ADIPOQ,ZNF593,DISC1,DNAJB2,CTNNBIP1,PSEN1,ADRB2,CAMK1,CPNE1,IFI16,NOG,HEY2,TFIP11,MIR148A,AKT1,RALB,BAG2,HFE,DKK1,TMBIM6,ADRB3,CYP2D6,SLPI,JUN,PLN |
| 3.544e-02 | -3.34 | RNA Polymerase I Promoter Escape | REACTOME pathways | R-HSA-73772 | 31 | 15 | 10285 | 3229 |
CDK7,MIR1304,ERCC3,MNAT1,POLR1D,GTF2H4,CCNH,TAF1D,POLR2F,RRN3,GTF2H5,POLR1H,POLR2L,POLR1B,GTF2H2 |
| 3.544e-02 | -3.34 | Inwardly rectifying K+ channels | REACTOME pathways | R-HSA-1296065 | 31 | 15 | 10285 | 3229 |
GNG3,GNB1,GABBR1,KCNJ2,KCNJ8,KCNJ3,GNG7,GNG10,GNG5,GNG2,GNG12,KCNJ10,GNGT2,GNB3,KCNJ11 |
| 3.545e-02 | -3.34 | Opioid Signalling | REACTOME pathways | R-HSA-111885 | 85 | 35 | 10285 | 3229 |
PPP2R1A,PPP3CA,OPRM1,PRKACB,PRKCA,GNB1,PPP1R1B,GNB4,GNG7,GNG2,PDE4B,GNG12,PDE1B,MIR197,PDYN,PLCB2,GNAI3,GNG3,ADCY2,CDK5,GNG13,PDE1A,GNAO1,GNG10,GNG5,GNG11,PPP2CB,PLCB1,ADCY3,GNAI2,AHCYL1,GNGT2,GNB3,GNAZ,CREB1 |
| 3.545e-02 | -3.34 | RHBDD1 (rhomboid domain containing 1) | protein interactions | 84236 | 337 | 110 | 19454 | 5460 |
SF3B1,RNF5,SEC62,PGRMC1,NOTCH2,TOR1AIP2,FAM8A1,ARCN1,VAPB,PRMT5,SEC61B,EFHD2,CYB5R3,PRRC2A,IP6K1,SPCS1,MANSC1,GABRG2,CGRRF1,MMP9,GPSM3,NDUFA4,GCA,SERPIND1,FAF2,SERPINA3,CARTPT,NUP153,YIPF3,TUBA1A,STBD1,MACO1,OR4N2,STIM1,KDELR1,CTSA,S100A8,NRSN1,SLC66A2,STX5,KCNA2,CHI3L1,HNRNPL,DDRGK1,BAZ1B,VCPIP1,PDAP1,LCP1,MTDH,RTN4,TEX264,TMEM209,YKT6,TTR,CD2AP,RABL3,ARHGAP1,SEC22B,TFIP11,LEMD3,TOX4,STOM,USE1,TMX4,CALML5,ALB,VAMP3,ATL1,CTTN,SCML2,SEC63,DAPK1,TUFM,GORASP2,BSCL2,NSDHL,FBXO25,TF,THRAP3,EEF1A1,LBR,SNAP29,PREB,CCDC47,C1QC,SERPINA1,OR6M1,CTLA4,TMEM31,C2CD2,PTPN1,SRPRA,COX4I1,EHBP1,CAMLG,TMPO,ARL6IP5,DNAJC1,TMED9,MARCHF4,PLG,TMEM199,EDEM1,EMC4,OSBPL8,MAP4,POR,TMEM42,ESYT1,RPL24 |
| 3.550e-02 | -3.34 | dephosphorylation | biological process | GO:0016311 | 215 | 76 | 18204 | 5365 |
PTPRQ,PPP3CA,MTMR2,PTPN22,ACP2,PPP1R12A,PPP2CB,PLPP4,PXYLP1,MTMR12,INPP5K,PTPN1,PTPN11,FBP1,PIP4P1,DUSP26,DUSP10,SDHAF2,CTDSP2,STK11,PTP4A2,FIG4,DUSP22,PIP4P2,DUSP18,DUSP3,DUSP14,NANP,PPP2R5E,MTMR6,DUSP19,DUSP1,PTP4A3,INPP5E,BGLAP,DUSP9,PTPN5,PPM1D,PPM1M,PPP2R5A,PPP2R1A,UBLCP1,OCRL,CDKN3,PDP2,CTDSP1,PPP2R3A,MTM1,PLPP6,PTEN,PPP5C,CTTNBP2NL,DUSP6,FRA10AC1,PPP1CB,INPPL1,PPP3R2,PTPN4,ALPL,PPM1B,PPTC7,TAB1,SSH3,ACP5,SACM1L,PLPPR1,PPM1G,PTPRZ1,THTPA,FBXW11,PPP1CC,ACP6,DUSP21,PTPMT1,UBASH3B,PPM1K |
| 3.550e-02 | -3.34 | glucose homeostasis | biological process | GO:0042593 | 215 | 76 | 18204 | 5365 |
FOXA3,PTPN11,STK11,AGER,ADIPOR1,LRRC8A,SMAD4,SELENOT,LEP,RMI1,KCNJ11,GCLC,PPP3CA,AKT1,RAB11B,INPP5K,DHPS,SESN3,TWNK,DBH,IGF1R,IL6,CLTRN,BGLAP,LEPR,MIR15A,ADIPOR2,GPX1,PLSCR3,MBD5,UCP2,RRAGA,ADIPOQ,PIK3CA,KCNB1,CRTC2,RAF1,SMAD3,ICAM1,OPRK1,SLC16A1,CYP7A1,SLC29A1,PPARG,CCDC186,CARTPT,CNR1,NPTX1,MIR146A,NCOA5,CYB5R4,PIK3R1,XBP1,PCK2,PIK3R2,PRCP,MIR320A,SMAD2,SESN2,FKBP1B,FOSL2,TRA2B,MIRLET7G,CMA1,CRY1,MIR16-1,BAD,NUCKS1,CYP11B1,OAS1,CAV3,LRRC8D,CMKLR2,PAX6,SIN3A,FABP5 |
| 3.553e-02 | -3.34 | AIM2 (absent in melanoma 2) | protein interactions | 9447 | 110 | 40 | 19454 | 5460 |
BANF1,XRCC5,NBN,PML,HIRA,SQSTM1,TRIM11,RING1,APPBP2,RBBP7,GTF2I,MSH6,ANP32B,MDC1,PSMC1,ZBTB39,STRBP,IKZF5,NUP153,DDX39A,JUN,ADNP,TFCP2,SDCBP,NCOA5,MTA2,LIG3,PARP2,ZBTB33,EEF1B2,TFE3,TRIM27,ZNF740,CACYBP,DDX50,SMARCA5,MOV10,ZSCAN25,H1-10,MECP2 |
| 3.553e-02 | -3.34 | HMGXB4 (HMG-box containing 4) | protein interactions | 10042 | 110 | 40 | 19454 | 5460 |
BRMS1L,RBBP4,NR1H2,SUMO2,SHPRH,AKAP17A,CNTROB,SRPK2,PHF12,SIN3A,SYNCRIP,H2AZ1,ZNF330,MYBL2,EED,UBE2I,GATAD1,KPNA1,BRD3,SMARCA5,CREBBP,STAC3,ZCCHC10,SMARCE1,H3C1,PHF1,MBD3,SSRP1,PML,NKAPD1,EZH2,CBX3,HSP90B1,MTA2,DNAJC24,STRBP,MTA3,UBL5,MX1,SAP30 |
| 3.569e-02 | -3.33 | NADK (NAD kinase) | protein interactions | 65220 | 79 | 30 | 19454 | 5460 |
SRSF12,EEF1G,KRAS,EP300,TESK2,FAM53C,RTKN,AGAP1,SDCBP,SIPA1L1,KIF1C,TOP3B,INPP5E,SRPK2,RBM42,KCTD3,EIF4E2,NUDT18,CAMSAP2,YWHAB,UBE2H,TIAM1,YWHAZ,MAP3K21,YWHAG,YWHAH,FAM110B,CUL3,SFN,MOV10 |
| 3.569e-02 | -3.33 | H2AC12 (H2A clustered histone 12) | protein interactions | 85235 | 79 | 30 | 19454 | 5460 |
FBXW7,TNF,COIL,MEPCE,PPM1G,PRKCB,METTL14,EZH2,NUPR1,HEXIM1,UBA52,H1-5,FBP1,ELK4,EEF1A1,IGFBP3,RFXAP,TXNRD3,NDN,VIRMA,ESR2,HP1BP3,AGR2,H1-10,H1-1,HNRNPD,CBL,HMGA1,CSK,H2BC9 |
| 3.577e-02 | -3.33 | INTS1 (integrator complex subunit 1) | protein interactions | 26173 | 164 | 57 | 19454 | 5460 |
ACACA,RPA2,HCST,PPP1CB,NPY2R,INTS6L,NPTN,TCEA1,VIPR1,SIRT7,RPA3,RIT1,ZNF687,CUL3,GPR17,OPRM1,MAD2L2,VIRMA,POLR2B,APLNR,POLR2F,IL2RA,INTS12,INTS10,EIF4A3,CYB5B,STK16,AQP3,EZH2,SOX2,RPAP2,MGARP,PPP2R1A,SUPT5H,COMTD1,TOP3B,SSRP1,SEM1,CD80,H3C1,KRAS,SKA1,RPAP3,OSTM1,SLC2A1,P2RY10,FAM174A,OPRL1,CDC5L,ILVBL,CDK9,PRNP,STARD3NL,RAC2,EED,PPP2CB,SSR2 |
| 3.586e-02 | -3.33 | PHIP (pleckstrin homology domain interacting protein) | protein interactions | 55023 | 193 | 66 | 19454 | 5460 |
SNRPD1,ZNF330,RPL10,VIRMA,BUB3,PCCB,CUL3,COPS7A,SMARCA5,MYC,NUP50,SIRT7,PML,XRCC5,RPA3,HSPA5,FOXP2,CLU,STAU1,NUCKS1,WDR77,SPTBN1,LARP4B,RPA2,LMNA,COPS2,MYEF2,COQ8A,H2AZ1,ZBTB2,DBT,CNTROB,TMPO,COPS7B,DCUN1D1,HDAC6,COPS5,HMGA1,IFI16,BRD3,FOXP1,AKAP8L,NCK1,CHCHD1,HAPSTR1,NKRF,GARRE1,COPS4,FOXP4,SSRP1,RERE,EGR1,VRK1,HNRNPK,NEDD8,H3C1,ZNF609,TBK1,TAF2,RHOBTB1,HBP1,CHMP4C,HDAC11,NECAP1,EZH2,CBX3 |
| 3.589e-02 | -3.33 | glutathione-mediated detoxification | BIOCYC pathways | HUMAN_PWY-4061 | 19 | 11 | 902 | 319 |
GGH,GSTA1,GSTA4,GSTP1,GSTM4,GSTM3,GSTM5,GSTK1,MGST3,GSTT1,MGST2 |
| 3.594e-02 | -3.33 | PARD3B (par-3 family cell polarity regulator beta) | protein interactions | 117583 | 43 | 18 | 19454 | 5460 |
CIB2,RBM5,SNRPD2,HNRNPL,VIRMA,H1-5,SFN,YWHAH,YWHAG,CTNNB1,SNRPB,EZH2,BICD2,RHOB,YWHAZ,CASK,PPP3CA,YWHAB |
| 3.594e-02 | -3.33 | FGD1 (FYVE, RhoGEF and PH domain containing 1) | protein interactions | 2245 | 43 | 18 | 19454 | 5460 |
CDC42,FBXL19,CUL3,SF3B5,OSBPL8,GGCX,MECP2,MRPL18,CCDC86,HP1BP3,CTTN,RIGI,CWC15,KRAS,ARF6,ELMO1,INA,RPL7 |
| 3.594e-02 | -3.33 | GPRIN3 (GPRIN family member 3) | protein interactions | 285513 | 43 | 18 | 19454 | 5460 |
FLOT1,CAV1,DIRAS3,KRAS,ARF6,NTRK2,IGF1R,GJA1,RAB35,NRP1,RHOB,AGR2,FGFR1,LAMTOR1,LAMP3,LAMP2,RAB2A,RAF1 |
| 3.594e-02 | -3.33 | TENT2 (terminal nucleotidyltransferase 2) | protein interactions | 167153 | 43 | 18 | 19454 | 5460 |
MIRLET7B,MIR141,MIR10B,MIR9-2,MIRLET7C,ESR2,MIR29A,BCCIP,MIR155,MIR9-1,MIR222,MIR29C,SOX2,MIR34B,CUL3,MIR21,MIR363,MIR145 |
| 3.594e-02 | -3.33 | RADIL (Rap associating with DIL domain) | protein interactions | 55698 | 43 | 18 | 19454 | 5460 |
TOP3B,GPR17,RAP1A,YWHAG,CCNH,HCST,YWHAH,SIGLECL1,YWHAZ,TEX19,YWHAB,MRFAP1L1,CD83,EFNB1,CHN2,LITAF,EGLN3,GNB1 |
| 3.594e-02 | -3.33 | PNPO (pyridoxamine 5'-phosphate oxidase) | protein interactions | 55163 | 43 | 18 | 19454 | 5460 |
NIPA2,LDLR,SRSF2,SLC25A32,PRCP,TOLLIP,HSPE1,FBXO25,HNRNPDL,RABIF,TXNRD1,GMPPB,AGTRAP,MTPN,ARL6IP6,CARTPT,TULP3,UBE2H |
| 3.594e-02 | -3.33 | CDCA4 (cell division cycle associated 4) | protein interactions | 55038 | 43 | 18 | 19454 | 5460 |
TCAP,PPP2R2C,KDM1A,SEPHS1,ENKD1,MAP2K6,FAM222B,PPP2CB,ZNF451,PPP4C,SUPT7L,PRMT6,FNDC11,DOK5,SUV39H1,XPO1,PPP2R1A,SHC3 |
| 3.594e-02 | -3.33 | CASP8AP2 (caspase 8 associated protein 2) | protein interactions | 9994 | 43 | 18 | 19454 | 5460 |
CREBBP,SUMO1,MX1,TRAF2,FAS,BCL2L1,GLUL,PML,TRIM21,PHF21A,UBE2I,KDM1A,SNRNP40,ASF1A,SUMO2,PIAS1,COIL,VIRMA |
| 3.594e-02 | -3.33 | ZMIZ1 (zinc finger MIZ-type containing 1) | protein interactions | 57178 | 43 | 18 | 19454 | 5460 |
SETD4,PHF21A,SMAD3,RIGI,CCR7,NUP35,VIRMA,HNRNPL,KDM1A,SATB1,AR,CTNNB1,TP53,RBPJ,HNRNPD,TBC1D4,SMAD4,BRCA1 |
| 3.594e-02 | -3.33 | Cul3 (cullin 3) | protein interactions | 26554 | 43 | 18 | 19454 | 5460 |
RAB8B,CRYZ,TAF11,KBTBD6,COPS4,CAND1,KCTD10,CORO1C,TNFAIP1,COPS2,BTBD10,KCTD20,KLHL7,KLHL24,AURKAIP1,SAP30,COPS7A,CUL3 |
| 3.594e-02 | -3.33 | TMEM230 (transmembrane protein 230) | protein interactions | 29058 | 43 | 18 | 19454 | 5460 |
AQP2,LMNA,RPN1,LAMTOR1,SSR1,LAMP3,MBLAC2,OTULINL,SEC62,CREB3,LAMP2,RAB5C,RPL28,KRAS,SGTA,ARL4D,HRAS,TMT1A |
| 3.600e-02 | -3.32 | PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2) | protein interactions | 5563 | 232 | 78 | 19454 | 5460 |
LEP,CDR2,TMOD1,E2F6,ACACA,PPARG,RPA2,WWP1,LRRTM3,PRKAB1,NRBF2,VPS28,SRSF2,UFL1,HSCB,CERS2,STAU1,PFKFB2,FLCN,APPBP2,TIFA,NUBP2,ARRDC3,RPA3,FOS,STK11,SERTAD3,HSP90AA1,LAMTOR1,YWHAZ,TXNIP,BRCA1,BTF3,NONO,MLF2,CSK,EMILIN1,SFN,PPP1R3C,MORC4,MAD2L1,TRAF1,KCTD9,UBE2I,DCLRE1C,SLA2,CCNF,OPTN,AVPI1,MID1IP1,GRAP2,SPRY1,STIM1,PRKAG1,GFPT1,TRAF2,ZNF397,GPT,PTGES3,SMN1,G3BP1,ANAPC11,RBBP7,PIK3CG,CLPB,MRFAP1,RB1CC1,AKAP8L,NAB2,YWHAB,ESYT1,YWHAH,WWP2,CCDC172,HNRNPL,DNM2,DFFA,GYS1 |
| 3.601e-02 | -3.32 | Fatty acid metabolism | KEGG pathways | ko01212 | 48 | 23 | 7161 | 2463 |
ACADSB,CPT2,ACAT1,HACD2,ACSL4,EHHADH,HACD4,CPT1B,HADHA,MECR,PPT1,MCAT,ACAA2,TECR,SCD5,HADH,ELOVL6,ACOX1,HACD1,FADS2,HACD3,ACACA,ACADS |
| 3.601e-02 | -3.32 | Fatty acid metabolism | KEGG pathways | hsa01212 | 48 | 23 | 7161 | 2463 |
ACAA2,TECR,HADH,ELOVL6,SCD5,ACOX1,HACD1,HACD3,FADS2,ACADS,ACACA,CPT2,ACADSB,ACSL4,HACD2,ACAT1,HACD4,EHHADH,CPT1B,HADHA,MECR,MCAT,PPT1 |
| 3.601e-02 | -3.32 | N-glycan processing | biological process | GO:0006491 | 17 | 9 | 18204 | 5365 |
GANC,FUT8,ST8SIA4,GNPTG,ST8SIA5,MGAT4A,MAN1A2,GANAB,MGAT4B |
| 3.601e-02 | -3.32 | peptidyl-threonine dephosphorylation | biological process | GO:0035970 | 17 | 9 | 18204 | 5365 |
PPP5C,PPP2CB,PPM1D,DUSP10,DUSP1,PPM1B,PPM1K,DUSP18,PPM1G |
| 3.601e-02 | -3.32 | endosome to lysosome transport via multivesicular body sorting pathway | biological process | GO:0032510 | 17 | 9 | 18204 | 5365 |
CHMP4C,CHMP2B,VPS4B,CHMP2A,CHMP5,CHMP1A,UBXN6,CHMP1B,VPS4A |
| 3.601e-02 | -3.32 | synaptic vesicle membrane organization | biological process | GO:0048499 | 17 | 9 | 18204 | 5365 |
SNAP25,STX1A,STX11,SYNGR2,SNAP29,SYP,SNAPIN,SYNGR1,SNAP23 |
| 3.601e-02 | -3.32 | phosphate ion transmembrane transport | biological process | GO:0035435 | 17 | 9 | 18204 | 5365 |
SLC25A11,UCP2,SLC25A3,VDR,SLC20A1,SLC25A10,SLC20A2,ANKH,SLC37A4 |
| 3.601e-02 | -3.32 | cellular response to leptin stimulus | biological process | GO:0044320 | 17 | 9 | 18204 | 5365 |
UGCG,FGF23,CCNA2,MT3,LEPR,ADIPOR1,LEP,PID1,MKKS |
| 3.601e-02 | -3.32 | POLA2 (DNA polymerase alpha 2, accessory subunit) | protein interactions | 23649 | 129 | 46 | 19454 | 5460 |
VIRMA,NCKAP1,MAD2L1,FRZB,TAX1BP1,SSH3,CTNNA1,POP7,RIT1,FAM219A,PDCD4,PIP4K2C,STN1,BTF3,RFC5,CUL3,CIAO1,EIF4E,PSMC1,POLD2,PRIM2,RPA3,RFC4,RBM23,HEXIM1,RPA2,CCNA2,IGFBP3,CAPN1,POLE3,TOP1,CCAR2,LDLR,POU5F1,HDAC6,YWHAH,XPO1,SSRP1,XPNPEP1,DCP2,KRAS,PCNA,CPE,CRELD1,EZH2,CDK8 |
| 3.601e-02 | -3.32 | PNKD (PNKD metallo-beta-lactamase domain containing) | protein interactions | 25953 | 129 | 46 | 19454 | 5460 |
PPIB,PPFIBP1,GOLPH3L,KLHL22,TBC1D5,ARL14EP,ARL2BP,ECD,DCAF11,DICER1,PHB1,ADD1,CETN3,EIF2B5,EIF2B2,EGLN3,RAMP3,IPO8,DDX39A,NCSTN,TNPO2,NUP37,CAMK1,DCUN1D5,SFXN1,NUP107,ADD2,EXOC5,GMNN,ILK,CCNF,KCTD9,RANBP6,ARMC6,ESR2,MAD2L2,TIMM10,MYL12B,EIF3J,STOM,ARMCX3,EIF2B3,TFIP11,RTF2,FDFT1,FBXO30 |
| 3.603e-02 | -3.32 | exocytic process | biological process | GO:0140029 | 61 | 25 | 18204 | 5365 |
GNAO1,YKT6,VTI1B,CPLX2,VPS18,SNAPIN,NLGN1,EXOC2,KCNB1,STXBP1,PPFIA3,SNAP25,PSEN1,STX11,SNAP29,NAPA,EXOC8,VAMP3,EXOC5,STX1A,EXOC1,EXOC3,SNAP23,CFTR,SYK |
| 3.606e-02 | -3.32 | Apoptosis | KEGG pathways | hsa04210 | 138 | 58 | 7161 | 2463 |
BCL2A1,PIK3R3,BAX,DFFA,PIK3CA,BAD,TNF,CASP12,AKT2,JUN,AIFM1,SPTAN1,EIF2S1,PARP2,TRAF1,LMNB1,TRAF2,BIRC2,MAPK10,BCL2L1,FASLG,IKBKB,CTSD,PIK3R1,KRAS,PIK3R2,AKT1,IL3,TUBA1B,ACTB,TUBA1A,GADD45G,GADD45B,HTRA2,MCL1,MAP2K1,AKT3,TNFSF10,DDIT3,BAK1,CAPN2,NFKB1,FAS,PMAIP1,NFKBIA,HRAS,ATF4,CTSC,CTSB,MAP3K14,RAF1,BIRC5,GADD45A,FOS,CTSK,CAPN1,LMNA,TP53 |
| 3.606e-02 | -3.32 | Apoptosis | KEGG pathways | ko04210 | 138 | 58 | 7161 | 2463 |
TNF,BAD,PIK3CA,DFFA,BAX,PIK3R3,BCL2A1,EIF2S1,SPTAN1,AIFM1,AKT2,JUN,CASP12,FASLG,IKBKB,BIRC2,TRAF2,BCL2L1,MAPK10,LMNB1,PARP2,TRAF1,AKT1,TUBA1B,IL3,PIK3R2,KRAS,CTSD,PIK3R1,ACTB,FAS,PMAIP1,BAK1,NFKB1,CAPN2,TNFSF10,AKT3,DDIT3,MCL1,MAP2K1,HTRA2,GADD45B,GADD45G,TUBA1A,RAF1,BIRC5,MAP3K14,CTSB,ATF4,CTSC,HRAS,NFKBIA,TP53,CAPN1,LMNA,CTSK,GADD45A,FOS |
| 3.608e-02 | -3.32 | KIF5A (kinesin family member 5A) | protein interactions | 3798 | 76 | 29 | 19454 | 5460 |
MAPK10,DDX39A,NUP62,KLC2,HEXIM1,METTL14,LMNA,VPS26B,SMN1,BACH1,TRIM63,STAU1,EXOC1,INSYN1,YWHAG,YWHAH,CREBBP,KXD1,YWHAB,MED4,YWHAZ,TRAK2,ANAPC2,CEBPG,TSG101,BMP1,DYNLL1,SYNE4,SPPL3 |
| 3.608e-02 | -3.32 | POLD2 (DNA polymerase delta 2, accessory subunit) | protein interactions | 5425 | 76 | 29 | 19454 | 5460 |
KRAS,H3C1,HSCB,POLDIP2,POLDIP3,POLA2,PRIM2,EIF1AD,EP300,P4HA2,PCNA,DISC1,ATG16L1,CDKN1A,TOP1,MAD2L2,PPP5C,POLE3,GPR37,CCNF,OPTN,LSM6,ANKRD49,RIT1,CCHCR1,POLD4,NAB2,MYC,XPO1 |
| 3.608e-02 | -3.32 | CBFA2T3 (CBFA2/RUNX1 partner transcriptional co-repressor 3) | protein interactions | 863 | 76 | 29 | 19454 | 5460 |
HMG20A,LDHA,CHRM4,ZBTB33,CBFB,ARMC8,YPEL5,ZBTB38,CRTAP,GAS8,SSBP4,LDB1,HDAC6,RUNX1,CUL3,ZMYND19,SYCE3,RANBP10,KDM1A,HDAC3,HAPSTR1,MKLN1,MAEA,GID8,ARHGEF6,GID4,SSBP3,WWP1,SSBP2 |
| 3.608e-02 | -3.32 | NARS2 (asparaginyl-tRNA synthetase 2, mitochondrial) | protein interactions | 79731 | 76 | 29 | 19454 | 5460 |
CBR4,TUFM,LAMP3,P2RY10,YWHAG,PFDN5,AUH,KLK5,TMEM70,SMCHD1,TAFAZZIN,NAA30,FAHD1,GATD3,YBEY,SSBP1,MRPL23,CHRM3,ACAA2,PDHA1,RPA2,RPA3,HSPD1,SLC25A10,RAB8B,ATG4C,FBXW7,HSCB,CHCHD2 |
| 3.608e-02 | -3.32 | MIR9-2 (microRNA 9-2) | protein interactions | 407047 | 76 | 29 | 19454 | 5460 |
MYEF2,EIF2AK2,SYNCRIP,FAM98A,HNRNPL,MATR3,TENT2,APOBEC3B,GRSF1,TRA2A,NONO,HNRNPA1,CRTAP,DDX1,IGF2BP1,HNRNPA2B1,RTCB,ZC3H11A,HNRNPH2,SF3B1,HNRNPK,HNRNPA0,TRA2B,HNRNPF,MARS1,RBFOX2,RBMS2,HNRNPH3,RARS1 |
| 3.608e-02 | -3.32 | INO80E (INO80 complex subunit E) | protein interactions | 283899 | 76 | 29 | 19454 | 5460 |
RAF1,ACTL6A,FAM161A,CD2AP,MORN4,EGR2,KLF3,SDCBP,RP9,TFPT,INO80C,PICK1,RUVBL2,GTF2I,PSMA1,KRAS,KPNA2,STAU1,RUVBL1,KLHL9,ZCCHC10,TNFAIP8,STK11,CDC23,BRD3,VPS72,CSNK2B,BRD9,KBTBD6 |
| 3.608e-02 | -3.32 | FOXK2 (forkhead box K2) | protein interactions | 3607 | 219 | 74 | 19454 | 5460 |
EP300,DCTN3,SF3B1,PPM1G,HIRA,BAP1,DVL2,ZBTB39,SAP18,NHP2,TGIF2LX,HDAC3,EIF5B,ZNF428,FAXC,SEC62,RFXANK,ADNP,KLF3,MACROH2A1,ING2,SMU1,ZNF330,LIG3,IRF2,SRPK2,VIRMA,RBBP4,DRAP1,BRMS1,KANSL3,SMARCA5,MYC,HNF1B,IL2,ATP1A1,ZYX,MAP1B,PAX6,AHCYL1,ABHD10,GTF3C3,THRAP3,ASF1A,RBBP7,NUP107,ELF1,TULP3,SAP30,ING1,SOX2,TP53,PHF23,RAF1,MAX,MTA3,TOP3B,SAP30L,MTA2,DMAP1,RB1,EEF1AKMT3,KIAA0513,SIN3A,NUP35,PRNP,BRMS1L,HNRNPL,TRIM35,HSPB8,XPO1,DPY30,UBXN6,GSTM3 |
| 3.608e-02 | -3.32 | NAAA (N-acylethanolamine acid amidase) | protein interactions | 27163 | 219 | 74 | 19454 | 5460 |
NLGN2,ZNF507,MGST3,SLC25A4,TUBB,DTYMK,GGT7,RMDN3,OAF,CHCHD6,SFXN2,CDIPT,FAM210A,SLC7A11,ICAM1,TAFAZZIN,SDF2L1,ATP1A3,SAMHD1,RUNX1,GGH,ITGAV,HSPA5,TMEM209,SYVN1,ITGA2,RLIM,ATP2C1,UGDH,TMEM263,FAM8A1,CHPF2,SLC25A3,TCP11L1,STX17,SAMM50,KDELR2,SLC35E1,TIMMDC1,DKC1,OS9,SLC25A12,FIBIN,EXT1,COX20,COQ8A,OCIAD2,MPDU1,SMG8,HAX1,ST3GAL4,IQSEC1,PROS1,EDEM1,LRFN3,PSEN1,EDEM2,SIAE,ERLEC1,MRPS11,GALNT12,PC,ART5,TMEM87A,RUSF1,SLC25A10,DHRS7B,CTNNA2,TUBA1A,CYB5R1,NDST1,CCDC47,PREB,PI15 |
| 3.608e-02 | -3.32 | MEX3B (mex-3 RNA binding family member B) | protein interactions | 84206 | 219 | 74 | 19454 | 5460 |
CCT2,YWHAZ,PIP4K2C,RC3H2,PAIP2,AP2A1,IGF2BP1,LSM14B,CASC3,FAM193B,RUSC2,CEP85,CUL3,TAB1,PRRC2A,VIRMA,SMAP2,AP2M1,MRPS34,LARP4B,NUFIP2,SUFU,AGO1,NUDT3,RBMS2,UBE2D3,FXR2,YTHDF1,MRPS7,G3BP2,MCRIP2,GID8,LSM12,SMG5,SMAD4,NOS1AP,TDRD7,SMG9,DDX1,SMG8,YWHAB,CNOT2,MOV10,CNOT8,YWHAG,YWHAH,SPATA2,EDC3,FAM98A,KIF3B,SNX18,MRPS23,WDR6,MRPS9,EIF4E2,FUBP3,GLE1,GPBP1L1,GTPBP1,MACO1,TBK1,TOP3B,YTHDF2,TNRC6C,TNPO2,G3BP1,CNOT7,CNOT6L,TRIP4,GARRE1,LSM14A,PABPC1,ZC3H7A,RTCB |
| 3.610e-02 | -3.32 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Hodgkin_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Hodgkin_lymphoma | 20 | 10 | 16828 | 4835 |
SSBP2,PIK3CA,PTEN,TNFAIP3,SF3B1,HRAS,KRAS,TP53,ETV6,JAK2 |
| 3.621e-02 | -3.32 | TOMM34 (translocase of outer mitochondrial membrane 34) | protein interactions | 10953 | 107 | 39 | 19454 | 5460 |
RPA2,DMAP1,RAF1,ATP5PB,KBTBD4,B3GNT2,CENPM,TIMMDC1,MND1,SNRNP27,GTF2E2,G3BP1,RBCK1,MRPS18C,UNC45A,SAR1B,ZYX,RPA3,CHORDC1,WDR12,ATOSB,HSP90AA1,OSGEP,AHSA1,PEA15,HNRNPD,DNAJC7,ATP6V1D,CABCOCO1,MOV10,CDC37L1,GGH,RPL35A,MED17,ACTB,SH3BGRL,HSP90AB1,DYRK1A,ZBTB2 |
| 3.621e-02 | -3.32 | CRTAP (cartilage associated protein) | protein interactions | 10491 | 107 | 39 | 19454 | 5460 |
MIR16-1,SURF2,SF3B4,MIRLET7B,TES,MIR9-1,MIRLET7G,POLR2B,TOM1L1,PRELID1,GRB10,VPS26A,FAM20C,CBL,MIR1-1,MIR140,RPA3,MIR10B,TMEM87A,SNRPA,TMEM106B,MIR9-2,MIRLET7I,MIR9-3,HSCB,MIR16-2,ZNHIT1,SNRPN,MIR200C,MGARP,CSTF2T,ZNF397,MIR17,P3H1,MIR20A,ACTR2,DISC1,SH3GLB2,NUPR1 |
| 3.628e-02 | -3.32 | RBD_domain_sf | interpro domains | IPR035979 | 242 | 84 | 18521 | 5414 |
EIF3G,RBM18,UHMK1,SF3B4,SYNCRIP,ELAVL2,RBM23,SNRPB2,RBM17,HNRNPAB,SF3B6,RBM41,LARP4B,HNRNPA2B1,CSTF2T,SRSF4,TIA1,CIRBP,SNRNP70,SRSF1,DDX50,RBM15B,SRSF10,EIF4H,TRA2A,RBM22,CELF6,ELAVL4,MYEF2,ZCRB1,MATR3,HNRNPH2,RRP7A,PSPC1,BRAP,TNRC6C,SNRPA,NUP35,HNRNPL,GRSF1,HNRNPD,BOLL,SRSF12,RBM27,HNRNPDL,G3BP2,HNRNPA1,SRSF7,IGF2BP1,PABPC1,HNRNPH3,RBM7,HNRNPA0,PPIL4,RALYL,HNRNPC,ALYREF,RBM5,NCBP2,RBM42,POLDIP3,RBMS2,SART3,AKAP17A,RBFOX3,UPF3B,PABPC5,HNRNPF,TRA2B,RBM12,NONO,RDM1,SRSF2,RBFOX2,G3BP1,LEMD3,RBM3,RBMX2,CPEB1,RBM34,EWSR1,RBM38,SRSF8,EIF4B |
| 3.632e-02 | -3.32 | alveolar_soft_part_sarcoma | COSMIC cancer mutations | alveolar_soft_part_sarcoma | 45 | 19 | 16828 | 4835 |
TP53,KIT,RB1,MET,CTNNB1,FBXW7,PTPN11,JAK2,AKT1,TERT,PIK3CA,FGFR1,PTEN,SMARCB1,HRAS,KRAS,IDH1,STK11,SMAD4 |
| 3.632e-02 | -3.32 | anaplastic_large_cell_lymphoma | COSMIC cancer mutations | anaplastic_large_cell_lymphoma | 45 | 19 | 16828 | 4835 |
PTEN,TPM3,FGFR1,PIK3CA,JAK2,AKT1,MSN,IDH2,RB1,KIT,MET,CTNNB1,TFG,TP53,SRC,STK11,IDH1,HRAS,KRAS |
| 3.632e-02 | -3.32 | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | 45 | 19 | 16828 | 4835 |
TP53,MET,RB1,KIT,CTNNB1,FBXW7,PTPN11,JAK2,AKT1,TERT,PIK3CA,FGFR1,PTEN,SMARCB1,HRAS,KRAS,IDH1,STK11,SMAD4 |
| 3.634e-02 | -3.31 | APOBEC3G mediated resistance to HIV-1 infection | REACTOME pathways | R-HSA-180689 | 5 | 4 | 10285 | 3229 |
HMGA1,BANF1,APOBEC3G,PPIA |
| 3.634e-02 | -3.31 | Sperm:Oocyte Membrane Binding | REACTOME pathways | R-HSA-1300652 | 5 | 4 | 10285 | 3229 |
CD9,IZUMO4,IZUMO1,IZUMO2 |
| 3.634e-02 | -3.31 | Extrinsic Pathway of Fibrin Clot Formation | REACTOME pathways | R-HSA-140834 | 5 | 4 | 10285 | 3229 |
F7,F9,TFPI,F10 |
| 3.634e-02 | -3.31 | Muscarinic acetylcholine receptors | REACTOME pathways | R-HSA-390648 | 5 | 4 | 10285 | 3229 |
CHRM5,CHRM1,CHRM3,CHRM4 |
| 3.643e-02 | -3.31 | RNA catabolic process | biological process | GO:0006401 | 172 | 62 | 18204 | 5365 |
POLR2G,ISG20,TENT4A,RNASEH1,EXOSC8,SMG9,LSM4,RNASEH2C,CNOT8,DBR1,LSM2,MAGOHB,CNOT6L,AGO1,DDX5,ELOC,NCBP2,LSM5,PDE12,ETF1,EIF4A3,PNRC1,HNRNPD,SKIC8,GRSF1,RNASE6,MAGOH,CNOT2,THRAP3,TENT2,RBM7,METTL14,CNOT6,TRIR,PYM1,WDR82,DICER1,ZCCHC7,CASC3,FEN1,SMG8,EXOSC4,DCP2,NUDT12,DIS3L,DXO,UPF3B,EXOSC3,PABPC1,EDC3,PPP1R8,EXOSC1,RNASET2,YTHDF2,PELO,RC3H2,CNOT7,EIF3E,NUDT16,SMG5,MRTO4,LSM6 |
| 3.643e-02 | -3.31 | GPHN (gephyrin) | protein interactions | 10243 | 73 | 28 | 19454 | 5460 |
UBE2H,ANAPC4,CUL3,HNRNPC,AKT1,YWHAG,SPTAN1,PRNP,DYNLL1,VIRMA,EGLN3,TSSK1B,CCNF,VPS33A,MTA2,POLR2C,UBE2M,TP53,NAA15,GLRB,PAAF1,MAP1LC3B,ROCK2,PSMA1,GABARAP,PRPF4,EP300,GPHN |
| 3.643e-02 | -3.31 | WDR37 (WD repeat domain 37) | protein interactions | 22884 | 73 | 28 | 19454 | 5460 |
H1-1,YWHAB,TADA1,CCT2,YWHAZ,TADA3,YWHAG,YWHAH,BAG3,PPP1CC,TAF5L,MOV10,CCT7,HNRNPL,TCP1,SUPT7L,CAPN2,FGFR1,SUPT3H,LEAP2,WDR37,ATG16L1,KRAS,SGF29,FBXW7,ATG4A,EWSR1,HSPA8 |
| 3.643e-02 | -3.31 | FZD7 (frizzled class receptor 7) | protein interactions | 8324 | 73 | 28 | 19454 | 5460 |
NCALD,TOP3B,TRAF2,HPCAL1,TRIM68,SCGB1C1,SIGMAR1,GOLGA5,TM9SF1,GNAI3,ATP2B4,DLG1,CERS2,TNFAIP3,EI24,TM9SF4,UPK1A,PDAP1,CREB1,DLG4,SGTA,CLN8,PRNP,ACP2,AIG1,MSMO1,TMEM237,VIRMA |
| 3.643e-02 | -3.31 | TCEAL1 (transcription elongation factor A like 1) | protein interactions | 9338 | 73 | 28 | 19454 | 5460 |
CITED1,EGLN3,USP5,PDCD5,CCNF,SCNM1,PHF7,DTL,ARL2BP,GMPS,ELOC,DYRK1B,POGK,CUL2,PTPN11,EYA3,FEM1C,SSR3,MCMBP,TRUB1,SETD4,RAB5A,FAF1,RTF2,FEM1A,DDX39A,TP53,UBL3 |
| 3.643e-02 | -3.31 | DAB2IP (DAB2 interacting protein) | protein interactions | 153090 | 73 | 28 | 19454 | 5460 |
RHOH,RHOJ,CDC20,MAD2L1,VIRMA,RAB35,HRAS,RAC2,SNX17,RHOG,YWHAZ,RHOB,YWHAB,PIK3R1,AKT1,XPO1,YWHAG,YWHAH,KRAS,SLC31A1,FBXW7,SKP1,CD83,EFNB1,CSNK1A1,TOP3B,TP53,TRAF2 |
| 3.649e-02 | -3.31 | cell junction organization | biological process | GO:0034330 | 532 | 176 | 18204 | 5365 |
CDH8,ACTB,CDH7,SMAD3,CACNB3,CX3CL1,CAPZA1,ESAM,SLITRK2,CCM2,CX3CR1,VMP1,TMEM108,LRRTM2,CNTNAP1,GABRB3,TMIGD1,CLDN4,NTNG2,CDK5,PTK7,HDAC6,STK38,CHRDL1,IL1RAP,SYBU,CBLN4,ASIC2,KCNJ8,DRD1,CACNB4,ZNF365,LRRC4B,FGF13,CTTN,GJA1,PRKCA,NEFL,CD2AP,NLGN2,STK38L,GLRB,CLDN3,ARF6,INA,PICK1,NPTX1,CDH11,PPFIA3,CACNB2,SDCBP,ZC4H2,ARF1,NLGN1,TESK2,ITGA6,RAB8B,STAU1,OCEL1,GABRA1,GNPAT,EXT1,MTMR2,SRC,SLC25A46,LAMB2,IGSF21,LARGE1,HSPA8,C1QL3,CLDN14,C1QL1,HOMER1,THY1,DLG4,CNTN2,GABRA2,GPM6A,MECP2,SLITRK1,GPHN,NF2,LRFN3,PRRT1,CHRNA7,SNCG,CLDN8,CLDN12,JUP,CLSTN3,ELFN1,CAP2,PCDHB13,RAB39B,TGFB2,PPFIA2,GJB2,SLC1A1,CTNNB1,RAB29,GJB1,GABRG2,MAP1B,CLDN9,WASL,WNT7A,SLC6A1,DKK1,C1QC,PKP4,TGFB3,CDH13,FKRP,WASF3,ITGA2,PIP5K1A,RER1,LIMS2,PTEN,NRP1,L1CAM,ACTL9,RAP1B,TUBA1A,GRIA1,GHRL,CTNNA1,TNR,FLRT3,SNAI2,PPFIBP1,CBLN1,PAK2,LHFPL4,RAB13,CRKL,DLG1,ADD2,LRRTM1,EPHA4,CBLN3,LRRC4,SNCB,FERMT2,CLDN22,IGF1R,CSK,FLCN,PCDH17,CDC42,CLDN6,PRNP,SNTA1,C1QL2,GPC4,PARD6A,ADGRL3,ACHE,CLDN24,CLDN11,SNAPIN,GJA10,DRP2,EFNA5,NOS1AP,OPHN1,GABRB2,ILDR1,NPTN,CBLN2,CLDN1,SLC39A9,CD9,GJC1,AJM1,PSEN1 |
| 3.652e-02 | -3.31 | TMPRSS5 (transmembrane serine protease 5) | protein interactions | 80975 | 46 | 19 | 19454 | 5460 |
YBEY,DECR2,MCL1,HSPA8,HNRNPL,TUBB,EDEM2,HSPA5,SLC25A14,FKBP8,TOR3A,TM9SF4,TOMM40,TUBA1A,FBXO7,CDC42SE2,TUBB4B,STX17,ICAM1 |
| 3.652e-02 | -3.31 | ZNF865 (zinc finger protein 865) | protein interactions | 100507290 | 46 | 19 | 19454 | 5460 |
PNMA2,TRIM23,TEX19,MRPS25,POU5F1,TOP3B,NOTCH2,RPL4,EIF2B5,RPL28,FTL,VIRMA,RPL17,MRFAP1L1,LTBR,LURAP1,FBLN5,PRR3,P4HA2 |
| 3.652e-02 | -3.31 | TM4SF18 (transmembrane 4 L six family member 18) | protein interactions | 116441 | 46 | 19 | 19454 | 5460 |
VAMP5,PMP22,STXBP1,FXYD6,CYB561,TMEM179B,TEX264,SLC39A9,RPRM,CD63,GGT7,RAP1B,EMP3,PYGM,NSG1,CXCL9,CD47,EFNA5,ACP2 |
| 3.652e-02 | -3.31 | RAD54B (RAD54 homolog B) | protein interactions | 25788 | 46 | 19 | 19454 | 5460 |
ATPAF2,NUDT18,UBE2I,TRMO,PSMA1,MDM2,EGLN3,ENKD1,CSNK1E,CUL3,SUMO1,CD2BP2,IGFBP3,GORASP2,NIF3L1,DYRK2,CDC23,TRAPPC6A,MAF1 |
| 3.652e-02 | -3.31 | KSR2 (kinase suppressor of ras 2) | protein interactions | 283455 | 46 | 19 | 19454 | 5460 |
HNRNPL,DNAAF10,PPP5C,PDRG1,RPAP3,MAP2K1,YWHAZ,NGB,HSP90AA1,YWHAB,PIH1D1,PFDN6,TOP3B,RAF1,YWHAG,CDC42,YWHAH,SOX2,GPRASP2 |
| 3.652e-02 | -3.31 | ACAP2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2) | protein interactions | 23527 | 46 | 19 | 19454 | 5460 |
ILK,UBE2H,HSPB1,MED4,UBE2M,ELK4,IFI16,APEX1,SMURF1,ARF6,UFL1,RAB5A,PTEN,HAPSTR1,AP2M1,EHBP1,RAB35,GPAA1,RPA3 |
| 3.652e-02 | -3.31 | TRIM47 (tripartite motif containing 47) | protein interactions | 91107 | 46 | 19 | 19454 | 5460 |
RAF1,ATG16L1,FBP1,TRIM8,CUL3,TP53,XAF1,SMAD4,BRCA1,NUDT5,TRIM44,PPP1R12A,EEF1AKMT3,MRFAP1,GANAB,TSG101,SATB1,MDM2,ESR2 |
| 3.654e-02 | -3.31 | RIP-mediated NFkB activation via ZBP1 | REACTOME pathways | R-HSA-1810476 | 21 | 11 | 10285 | 3229 |
NFKBIA,MYD88,DHX9,S100B,TICAM1,NFKBIB,NFKB1,IKBKB,TLR3,AGER,HMGB1 |
| 3.654e-02 | -3.31 | PI-3K cascade:FGFR1 | REACTOME pathways | R-HSA-5654689 | 21 | 11 | 10285 | 3229 |
PIK3CA,FGF22,FGFR1,FGF23,PTPN11,GAB1,FGF1,FGF10,FGF17,PIK3R1,FGF3 |
| 3.655e-02 | -3.31 | EHMT2 (euchromatic histone lysine methyltransferase 2) | protein interactions | 10919 | 278 | 92 | 19454 | 5460 |
LRWD1,CCT7,TCP1,EED,LHX2,POU5F1,CSTA,HSPB8,UBXN6,PAX6,RERE,MX2,RUVBL1,CHCHD2,LASP1,PSMA1,RUVBL2,PCNA,HGS,ITGB5,H2BC1,IRF8,EZH2,SOX2,GFI1,MAX,MAD2L2,ESR2,MAD2L1,CBX5,ZMYM2,ELK3,RIT1,H1-1,PSMD14,THAP7,CUL3,LMO2,DSN1,COIL,KLF3,MED23,CTBP1,RFXANK,PSMB3,H1-5,KLF9,NAA11,TWIST2,ARL4D,AIFM1,H2AZ1,BRD3,ZNF688,PTGER4,E4F1,SUV39H1,CSNK2A1,MOV10,RNF20,H3C1,RING1,CBX3,CHAMP1,CDK8,ESS2,H2AX,PHF13,TP53,ABHD17A,GPX1,MACROH2A1,CSNK2B,TUBA1B,EIF4A3,IGF2BP1,ZBTB38,LACRT,DNAJC8,AR,CSK,FBXW7,KDM1A,MIS12,PML,BANF1,PAX9,LMNA,RPA2,KLF12,MED30,FAM161A |
| 3.665e-02 | -3.31 | sterol biosynthetic process | biological process | GO:0016126 | 44 | 19 | 18204 | 5365 |
ERG28,CFTR,CH25H,CYB5R3,FAXDC2,NPC1L1,MSMO1,G6PD,HMGCS1,NSDHL,CYB5R1,LIPA,SC5D,MVD,INSIG2,LBR,FDFT1,ACAA2,PLPP6 |
| 3.665e-02 | -3.31 | regulation of cell fate commitment | biological process | GO:0010453 | 44 | 19 | 18204 | 5365 |
MBD3,AR,MIR1-1,IL23A,MTA3,MTA2,RBBP4,NKX6-2,IL12B,BMPR1A,MIR206,DKK1,SOSTDC1,PAX6,RBBP7,LMO4,FGFR1,MIR208A,EP300 |
| 3.674e-02 | -3.30 | C1QL4 (complement C1q like 4) | protein interactions | 338761 | 70 | 27 | 19454 | 5460 |
LCN9,TNFSF8,ADIPOQ,GNG5,SFTPC,GNAQ,NCR3,TMEM106A,CBLN4,GNG10,FNDC9,YES1,CSTF3,CD1A,SRC,HRAS,ELSPBP1,SSMEM1,SGTA,PPP2R5E,SDF2L1,TAFAZZIN,SLC38A1,TMEM179B,BTN2A2,RHCG,FATE1 |
| 3.674e-02 | -3.30 | EPM2AIP1 (EPM2A interacting protein 1) | protein interactions | 9852 | 70 | 27 | 19454 | 5460 |
CSNK1A1L,MAD2L1BP,TFIP11,CSNK1A1,MX1,SOX2,TRA2B,EMP2,NOC4L,ZBTB14,PICK1,FHL3,TNFAIP1,BRCA1,CBL,FAM20C,OTUD7B,AR,LDB2,TRIM54,KCTD9,PRNP,CNTROB,MAD2L1,CITED1,CCNF,TNKS |
| 3.674e-02 | -3.30 | GPC4 (glypican 4) | protein interactions | 2239 | 70 | 27 | 19454 | 5460 |
SOX2,TOP3B,LRRTM3,EZH2,TFCP2,SPCS2,HADHA,SQSTM1,ACP5,PICK1,HSPA5,CLEC12B,CAMKV,BAG3,HBEGF,FGF1,LCN6,PIK3R3,DPP4,CD36,PTEN,ADAM21,CCNF,SRP14,LMBR1L,SPCS1,ABHD17A |
| 3.674e-02 | -3.30 | TSHZ3 (teashirt zinc finger homeobox 3) | protein interactions | 57616 | 70 | 27 | 19454 | 5460 |
TRIM54,TAX1BP1,RBBP4,PTP4A3,ANKRA2,CPSF1,APEX2,TRIM27,MAB21L1,PHF21A,TRIM23,CCHCR1,LHX2,LRRC73,GPRASP2,GAPDH,CEP70,KDM1A,PAX6,RPA3,RINT1,KLF3,RPA2,CTBP1,TFIP11,TRAF2,SOX2 |
| 3.674e-02 | -3.30 | PGAM2 (phosphoglycerate mutase 2) | protein interactions | 5224 | 70 | 27 | 19454 | 5460 |
HDHD3,DNASE1L1,CLVS2,TENT5C,TXN,GNB1,MDM2,PGAM1,DNAJB2,GAPDH,VASH1,DCAF5,ILK,USP15,DNAJC4,TNNC2,KATNAL1,VDAC1,BPGM,PXMP2,TP53,CFTR,LPAR6,TMEM106A,CCM2,EZH2,TUBB4B |
| 3.674e-02 | -3.30 | GGCX (gamma-glutamyl carboxylase) | protein interactions | 2677 | 70 | 27 | 19454 | 5460 |
DERL1,CXCR4,HNRNPDL,PAEP,HSCB,PRRG1,DCP2,SEC62,HCST,OTULINL,RAF1,AP1S2,AQP3,GP9,F10,PHB1,B4GAT1,ESR2,SRPK2,RAMP3,APLNR,F7,GPBAR1,F2,CUL3,F9,BGLAP |
| 3.677e-02 | -3.30 | RNA Polymerase II Pre-transcription Events | REACTOME pathways | R-HSA-674695 | 88 | 36 | 10285 | 3229 |
GTF2H5,POLR2L,POLR2D,GTF2H2,TCEA1,TAF10,TAF7,POLR2F,GTF2F2,GTF2A2,TAF9,SUPT4H1,POLR2G,ELOC,MNAT1,NCBP2,EAF2,POLR2B,SUPT5H,TAF2,GTF2E2,CDK7,GTF2E1,POLR2I,GTF2F1,CDC73,GTF2A1,SKIC8,GTF2H4,CCNH,POLR2C,TAF11,GTF2B,SSRP1,ERCC3,CDK9 |
| 3.681e-02 | -3.30 | cyclin-dependent protein serine/threonine kinase regulator activity | molecular function | GO:0016538 | 49 | 21 | 18094 | 5411 |
CDKN1B,CCNY,CCNH,CNPPD1,CCND1,HEXIM2,CDK5R1,CCNQ,CDKN2C,CDKN1A,CCNF,CCND3,HEXIM1,CDK4,CDKN2D,CKS1B,CCNB1,CCNA2,MNAT1,CKS2,CCNI |
| 3.684e-02 | -3.30 | human chr6q22.32 | chromosome location | human chr6q22.32 | 4 | 3 | 26134 | 5823 |
HINT3,CENPW,TRMT11 |
| 3.685e-02 | -3.30 | dendrite morphogenesis | biological process | GO:0048813 | 64 | 26 | 18204 | 5365 |
MEF2A,RERE,SLITRK5,SDC2,TMEM106B,CHRNA7,CDC42,ZNF365,SLC11A2,TPBG,PTEN,IGF2BP1,NRP1,VLDLR,HDAC6,DLG4,PTN,PICALM,WASL,PPP3CA,WNT7A,ELAVL4,CDK5,PHACTR1,CTNNA2,ABITRAM |
| 3.685e-02 | -3.30 | regulation of ATP-dependent activity | biological process | GO:0043462 | 64 | 26 | 18204 | 5365 |
METTL21A,VMP1,ATP1B3,FGF10,AHSA1,TP53,TNNT2,VCPKMT,PPIF,DNAJB2,PLSCR1,DNAJC24,SNRNP70,ATP5IF1,TOR1AIP2,MSH6,ATP1B1,SSBP1,UBLCP1,DHX9,DNAJC10,CHTOP,RGN,PLN,TLR9,GABARAPL2 |
| 3.688e-02 | -3.30 | neuron projection | cellular component | GO:0043005 | 1331 | 416 | 19108 | 5553 |
GSK3A,UBB,SOD1,CHRNB2,ABHD12,DLG3,PLPPR1,CCN3,BMPR2,SLC1A2,MTMR2,CPLX3,ORAI2,ABHD17A,SYBU,BMPR1A,GABRB3,MPP1,PDYN,LPAR1,ATL1,CYFIP2,SLC6A1,PTEN,GLRA2,CMKLR2,BECN1,BLOC1S5,CYGB,SNCG,KCNA2,NTRK3,TXNRD2,TBC1D24,MAP1S,INPP5K,CDC42,GNAQ,RAB39B,VEZT,NEGR1,TIAM1,ELFN1,CDH8,EMX2,LHFPL4,CNTNAP1,LYPD6,DAG1,UFL1,KCNB1,SPOCK1,DLG4,HTR2A,EIF4A3,TRAPPC4,PSMD10,SNAP25,SIGMAR1,CTTNBP2,AP3S2,TGFB2,ARF4,NGDN,CHRNA7,GPM6A,ATP1A3,GABRB2,DLG1,KLHL24,GLRA1,TPBG,HSP90AA1,SYT2,KCNAB1,STMN2,ACTL9,LRFN3,GABBR1,P2RY1,VAMP3,EXOC8,CX3CR1,AZIN2,JPH4,LRRC4B,PPT1,EPHB6,CNTN2,CRHBP,MCHR1,CCR2,PSD2,RIC3,RTN4,TNFRSF1B,FXR2,TMEM237,NPY1R,GNAZ,SLC4A8,CRHR1,RIT2,MORN4,MKKS,SCN1B,NLGN2,KIF1C,C9orf72,SMN1,WDR19,GRM2,NDFIP1,SLC4A10,MME,LYNX1,PCSK2,NPY5R,TRIM3,PDE4B,FAM161A,TMIGD1,PROM1,PPP2R1A,SSNA1,ARMCX3,HYCC1,ATF4,OCRL,ASIC2,HTR1F,LYAR,ZC3H14,CDK5R1,KCNC1,SLITRK2,SLC6A6,SYT4,MAX,NRP1,SLC32A1,OPRL1,FCGR2B,CBL,LRRC4,NQO1,CTNNA2,CHRM1,ADORA3,GNB1,ARF1,LGI3,UHMK1,GPR37,ADAM21,OTX2,TENM3,PPFIA2,HSPA8,TRIM46,FBXO7,SNAPIN,NTRK2,PRKCB,STX1A,GRM1,TMEM185A,SNAP23,GNAO1,PGRMC1,ABITRAM,HAPLN2,NF2,ATP6AP2,ATP1A1,TRAK2,MAP1B,IL6ST,GLRX5,RAB27A,BGLAP,KCNH1,GNA11,NTF4,FEZ1,SRC,CX3CL1,GPHN,STAU1,L1CAM,CHRM5,FCHSD2,NEO1,SLC1A1,RGS6,KCNJ2,SYNPR,CD200,MT3,GNB3,IGF1R,TOPORS,GRIA1,UCN,RAB5A,NPR2,FKBP4,ATAT1,FAM168B,PTK7,CLSTN3,GRIA2,EXOC3,KCNIP2,PTPRQ,KLHL1,OPHN1,SIPA1L1,LCA5,SLC1A3,TUBG1,SARM1,IGF2BP1,VIP,GCHFR,CAMK2G,CRMP1,NTNG2,ATXN10,GLRB,NSG1,OPRM1,NPBWR1,RGS7BP,NRSN2,KCND2,ATP1A2,NETO1,CPEB1,SNX14,LAMP5,PPP3CA,CALY,CASC3,CAPN2,IFT52,RPL28,SLC38A2,FLRT2,PPP1CC,ATXN1L,CNTN1,PSEN1,NHERF1,USP8,RAP1A,ITGA2,ADORA1,MPST,ADCY2,CLRN2,LGI1,EPHA4,GABRA2,ROGDI,VAMP2,PCDH9,SLC12A2,CLRN1,NCDN,PNOC,SNCB,BAALC,GRXCR1,BLOC1S3,PRSS12,HSBP1,TACR3,IFT57,GNG13,BAG2,C1QL1,MAP4,ADNP,MAP3K12,TACR1,KCND3,CPLX2,RNF40,BLOC1S2,TPH2,CDH13,CAMK2N1,HPCA,DYRK1A,PICK1,CYP17A1,BMPR1B,SPTBN1,DISC1,FZD4,PQBP1,HDAC6,SMURF1,CSNK1E,FAM107A,DRP2,INHA,BRINP1,SLC6A4,DYNLL1,CFL1,CACNG3,FGF13,CHRM3,HRH2,HTR1A,BRINP2,HRH3,PDLIM4,NLGN1,PACRG,RCVRN,SLC8A1,CD40,TTC8,GLRX2,AMIGO1,SRSF10,ERO1A,GABRG2,CPLX1,FUBP3,HSP90AB1,LRRTM1,CIB2,BRINP3,CYTH2,TMEM108,CLU,VAMP1,GHRL,EPS8,YKT6,CCSAP,ABHD13,CTTN,PRNP,OPRK1,HTR5A,FBXW11,ELAVL4,KCNA3,RPGRIP1L,SYNDIG1,ALCAM,MTPN,HSPB1,EIF4EBP2,COMT,PCDHB13,GNG3,HOMER3,NEFL,THY1,SYP,STOML3,RASGRP2,RBM3,STXBP1,MGARP,RAB3A,CHRM4,BACE1,CETN2,GAD2,KPNA1,SLC6A3,CETN3,FLRT3,KCNJ11,TAC1,SLC6A2,DHRS3,RAB13,SEPTIN6,NRSN1,STAT1,KIF3B,CD2AP,FZD3,ARPC3,PHB2,MOB4,TMEM266,DRD1,ELK1,DNM2,MUL1,GNAI2,PDE6A,CNR1,CTNND1,GABRA1,ARPC2,VAMP7,PAFAH1B1,ACTB,CRYAB,ADGRL3,SLC38A7,HOMER1,CLDN11,SLC38A1,MACO1,CDK5 |
| 3.689e-02 | -3.30 | GTF2H1 (general transcription factor IIH subunit 1) | protein interactions | 2965 | 104 | 38 | 19454 | 5460 |
RPA2,RAD23B,POLR2C,GTF2H5,AGTRAP,TP53,GTF2H4,GTF2E2,ZSCAN1,CDK7,CCNH,PRMT2,KRAS,PRPS1,MNAT1,SSRP1,RNF11,TCEA1,CLK1,RIT1,BRD3,TXNRD2,PIK3R1,MYC,ERCC3,AR,GTF2E1,RPL35,KLF1,TTC9C,ESR2,CETN2,DYRK1A,CCSER2,RB1,GTF2H2,GTF2F1,CDC7 |
| 3.689e-02 | -3.30 | UQCC1 (ubiquinol-cytochrome c reductase complex assembly factor 1) | protein interactions | 55245 | 104 | 38 | 19454 | 5460 |
HSPD1,UQCC2,NGRN,CXCR4,NDUFA4,COX8A,SRSF2,LPAR1,EDEM2,MRPS18C,FASTKD5,NRBF2,UNC45A,CLSTN3,CSNK1E,MRPL11,MRPL10,P3H1,SYS1,PDHA1,CDR2,AP2S1,MTRES1,CDIPT,COX20,GATD3,SLAIN2,JUNB,FGFR1OP2,GRSF1,TM2D2,AUH,PMPCA,MRM2,TUFM,CDH13,MRPS26,SLX1A |
| 3.694e-02 | -3.30 | ZNF292 (zinc finger protein 292) | protein interactions | 23036 | 49 | 20 | 19454 | 5460 |
SOX2,SUV39H1,TULP3,ZDHHC15,CBX3,ADNP,TIAM1,LDLR,NUP50,ALB,ZNF330,CBX5,LRIF1,COIL,APEX1,VIRMA,ESR2,H3C1,FBXO22,STAU1 |
| 3.694e-02 | -3.30 | STARD3NL (STARD3 N-terminal like) | protein interactions | 83930 | 49 | 20 | 19454 | 5460 |
GPAA1,ATP5PF,CHRM5,CD63,TMEM106B,LPAR2,TNFSF8,LPAR1,SLC25A4,ELK1,SYNJ2BP,ST3GAL1,TOMM22,TMEM231,ATP5PB,HCST,AGPAT5,ENDOD1,STOM,GPR35 |
| 3.694e-02 | -3.30 | GPR173 (G protein-coupled receptor 173) | protein interactions | 54328 | 49 | 20 | 19454 | 5460 |
YIPF3,CNNM4,RABL3,SURF4,ATP1A3,SIGMAR1,GOLGA5,XPO5,SLC39A10,SLC30A7,GPAA1,SNCG,CDIPT,ATP2B4,VKORC1L1,ACP2,ARL6IP5,CERS2,CMTM6,DERL2 |
| 3.694e-02 | -3.30 | ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide) | protein interactions | 128 | 49 | 20 | 19454 | 5460 |
BAP1,RPA3,CMBL,SLC66A2,CSNK2B,AKR1C2,PTPN4,ESD,PRDX1,SPR,TP53,PGM1,RPA2,SNTA1,NUDT19,AGR2,NDUFS6,SOD2,MT1X,NQO1 |
| 3.694e-02 | -3.30 | WDR5B (WD repeat domain 5B) | protein interactions | 54554 | 49 | 20 | 19454 | 5460 |
TUBA1A,TMEM266,SNRNP27,DDX39A,CFTR,CCT2,DCAF4,HSPA8,NUDT9,WDR6,TMEM263,MAGED4B,CCT7,PRDX4,SELENON,TXN,RPIA,TCP1,FTSJ1,GPIHBP1 |
| 3.694e-02 | -3.30 | ASB14 (ankyrin repeat and SOCS box containing 14) | protein interactions | 142686 | 49 | 20 | 19454 | 5460 |
SLC25A5,HSDL1,PTPN1,AKAP1,SYBU,PHB2,VDAC1,RPS16,FKBP8,ARF4,NOTCH2,SLC25A1,ELOC,TUFM,TOMM40,TUBA1A,ESYT1,CYC1,RPL23,OSBPL8 |
| 3.694e-02 | -3.30 | WDR45 (WD repeat domain 45) | protein interactions | 11152 | 49 | 20 | 19454 | 5460 |
CISD1,RAB4A,HDAC11,ATG3,LCN8,TMOD1,CSNK1A1,RAB2A,CUL3,EDEM1,MAP1LC3B,ATG7,XPO1,ARF6,DUSP26,PLGRKT,APEX1,RIGI,SLC25A11,RAC2 |
| 3.694e-02 | -3.30 | MCRIP1 (MAPK regulated corepressor interacting protein 1) | protein interactions | 348262 | 49 | 20 | 19454 | 5460 |
YWHAH,YWHAG,MOV10,MYC,YTHDF2,KLF3,LSM12,ZC3H7A,RTCB,PSPC1,SMAP2,PHB1,PABPC1,METAP2,FUBP3,EGLN3,RPS16,G3BP1,FZR1,YTHDF1 |
| 3.694e-02 | -3.30 | RPP14 (ribonuclease P/MRP subunit p14) | protein interactions | 11102 | 49 | 20 | 19454 | 5460 |
POP5,EXOSC8,RPP21,CLIC2,MOB3C,ATG3,NOVA1,PSME1,POP7,ESR2,IGSF21,RPP25,RPP14,CDSN,RPP25L,ATP5F1B,HSCB,NPM3,SPPL3,KRAS |
| 3.694e-02 | -3.30 | CGGBP1 (CGG triplet repeat binding protein 1) | protein interactions | 8545 | 49 | 20 | 19454 | 5460 |
CAMSAP2,RBPJ,SDCBP,GORASP2,SNRNP27,NTAQ1,CDKN2D,MYC,RAF1,AKT1,APEX1,PAX6,CGGBP1,BOLA2B,FBXW7,KCTD17,PLEKHF2,EP300,UBE3A,PICK1 |
| 3.694e-02 | -3.30 | OSTC (oligosaccharyltransferase complex non-catalytic subunit) | protein interactions | 58505 | 49 | 20 | 19454 | 5460 |
RPN1,RPA2,SMAD4,GPR35,PICALM,RIT1,OST4,RAB2A,SCN3B,PGRMC1,TIA1,KRAS,UFL1,FKBP8,ESR2,SLC39A9,RPA3,STT3A,DPEP1,EED |
| 3.694e-02 | -3.30 | LYRM7 (LYR motif containing 7) | protein interactions | 90624 | 49 | 20 | 19454 | 5460 |
NDUFAB1,ISCU,KLHL22,AUH,MRPL11,MRPS26,AP2A1,PDHA1,SAT1,HINT2,GFM1,GATD3,PC,OPTN,HSPD1,FASTKD5,CA10,HNRNPL,HSCB,GRPEL2 |
| 3.698e-02 | -3.30 | cell surface receptor signaling pathway | biological process | GO:0007166 | 1992 | 622 | 18204 | 5365 |
FAM83A,CCR4,FGF16,SYK,RAB14,CD40,CCL23,OTULIN,ACVR1B,FCGR2B,NOG,NME2,FBXW7,CCAR2,ADIPOR1,STAP1,STK11,LMBR1L,ALKAL1,PLP2,CD2,PARP2,DUSP22,CSRNP1,SMAD3,RAP1A,PIK3AP1,COL1A2,KLRC2,WNT2,BIRC2,YES1,GPR171,CLEC12B,CTNND1,PLN,CD38,CD2AP,GLRB,NDP,TICAM2,TRAF6,RAB5A,MIR183,RARRES2,TLR2,FRS3,CSNK1A1L,PIAS1,CCL19,P2RY11,TLR5,GRM2,ADGRE2,MIR32,CTLA4,STAT5A,TBK1,CCL2,DISC1,KLRF1,HCLS1,FOS,NHERF1,IL2RA,FBXW4,BMPR1B,NPPC,NUP62,SOSTDC1,PML,ARL6,CRADD,NFKB1,WBP1L,CACNB4,IL15RA,GPR75,TMEM231,CCL4L1,PLP1,CSH1,IL18,SST,RB1CC1,TNFSF12,EXT1,ANGPT1,SRC,PHB2,PSEN2,LEP,FASLG,CD40LG,RNF41,THY1,WIF1,PDE4B,CD47,PIK3CA,WDR12,TIAM1,IL17F,RNF146,NLE1,PAFAH1B1,IFT52,NTF4,IFNG,DOK5,P2RY12,PDCD4,LGR4,PIK3R2,CUL3,PIK3R1,WDR19,CCL1,OSM,IRF1,FZD4,NTRK2,FLRT2,NTRK3,EIF2B5,BEX3,SHOC2,CTNNBIP1,IL15,TICAM1,SMAD9,MECP2,BCL9,FGF23,BMPR1A,SEMA7A,VEGFA,ADGRG1,BMPR2,LILRA1,MOG,LPXN,UBASH3B,WNT7A,PPP3CA,ITGB5,FAM53B,P2RY4,SIAH2,TGFB3,IL1B,CLEC1A,DELE1,AKT1,IFNA13,NCR3,GABARAP,GRB10,FKRP,SMAD4,TANK,ITGA2,SEMA3C,B9D1,EP300,NFKBIA,APH1A,IGF1,FAM83C,SKIC8,BOK,TAX1BP3,GPR34,PIK3R3,GID8,NPR2,BAK1,SLC1A1,CTNNB1,GH1,OXTR,IFT25,CXCL11,CCL24,MT3,TOLLIP,MET,CPE,GRIA1,CD59,INSYN2B,SIVA1,FLRT3,GNAI2,KIT,MLLT11,CD14,FAS,TGFBR2,IL2,MIR221,PAK2,CCND1,SS18,CRKL,NCOA5,LAT2,AR,KLRD1,UBE2N,PTEN,JAK2,LIMS2,BCL2L1,TIRAP,LRP6,NRP1,VLDLR,STAT1,FGF1,GSK3A,PRKCE,TMEM88,DVL2,TUBA1A,DEDD,GRID1,BAD,UGCG,RGMA,G0S2,KRT8,PLXNC1,JUN,PRL,CD79B,AKT2,GRIK1,ERRFI1,CD274,FOXP3,MX1,OXSR1,GRM1,HAX1,GPC4,GPR37L1,TRAF7,VEGFC,IFNGR1,ACVR1C,STOML2,TMEM100,SLC2A8,CXCL9,FCER1G,IL12B,FGR,CHRM4,CSK,NDST1,IL6,BAX,TRAF3IP2,STAMBP,SPG21,CAMLG,ADIPOR2,PTP4A3,IFNA10,GNAQ,CD86,MMP9,SMURF1,TNFRSF1B,PLCB1,IFNK,MCL1,JAK1,LCP2,MSX2,SEMA4C,GRIA2,LILRA2,CXCL3,CDC73,INHA,TNIK,IFNA2,FGFBP1,MIR21,IFI27,PAX6,SIN3A,GMDS,NMI,EDNRA,VAV2,TXNIP,CFC1,WNT10B,CLEC6A,ZBTB33,BCL2A1,SIPA1L1,CD36,CD80,ANXA4,NUS1,INSYN1,MBL2,STUB1,FGF7,BCL7B,CDK5,MPIG6B,PTK7,CXCR1,HFE,EPHA2,CXCL12,ITGB8,CXCR4,TMEM198,EPHB6,MAPK10,IL1RAP,CHRDL1,HRAS,PYCARD,ZNF304,AGER,FGF17,ZC3H15,TNF,CCR3,TWSG1,FGF3,RBPJ,XCL1,GRM8,RAF1,CACNB3,CX3CL1,TRAF2,CCM2,CX3CR1,MSX1,FCGR2A,TRAF1,EDA2R,LY96,MS4A7,PHB1,PDIA3,DDR1,CXCR3,LDB1,ACVR1,CNTN1,CCL25,FUT8,TIFA,CCR2,F2,FOXC2,SLC29A1,TMEM126A,MAPKAPK3,CSNK2B,PDCD1LG2,CXCL10,TNFRSF14,NDN,GLRA2,TMSB4X,FBXW11,ILK,CCL18,GPHA2,EID2,GREM2,CTTN,RB1,CITED1,VIPR1,GNG7,MRGPRX1,PSENEN,TIMP4,PRDX2,NKAP,TSHR,FGFR1,P2RY1,PLPP4,ITGAV,ACKR3,GHR,LILRA3,ADORA3,ADORA1,FGF22,PTPN1,CCL8,PTPN11,HOMER1,MICB,CCL11,ZBED3,KLF4,DDIT3,TLR4,CDK6,BLOC1S2,RRAGA,CXCL8,CCNY,SPPL3,FKBP8,MADCAM1,TP53,STK4,AZI2,IL21,CLEC7A,SOST,MITF,ITGA6,DDX5,MIR34A,LEPR,CD3G,CDKN1B,GAB1,SUFU,HOMER3,IRAK4,PRKCQ,JUP,SLA2,MIR212,PPARG,NSDHL,FCMR,CXCL13,CD247,MIR30A,DAAM1,SFRP4,CSNK1A1,EPO,MIR638,NR4A2,SIAH1,MKKS,IL34,IKBKB,TGFB1I1,RBCK1,EGR1,NCSTN,FZD6,CHRNB2,IL3,CHRNA7,IL7,EIF2B2,ITK,COL3A1,CXCR6,PTPN22,DKK1,CCR7,DDIT4,STAT6,ISG15,CCR6,VPS4B,SEMA5A,ADRB2,CREBBP,TNFSF18,CXCL1,SLC31A1,CCL20,MTDH,KLHL12,NOTCH2,FCN2,IL1A,TGFB2,FGF10,NCK1,JAGN1,IL2RG,EIF2B3,ADAMTS1,TLE1,CSNK2A1,GHRL,HBP1,CCL21,IL1R2,CBL,SOX9,STAT2,CCR5,CTNNA1,BAG3,FZD3,FMOD,EFNB1,SNAI2,BECN1,CHST11,EIF4EBP2,IRF7,CD200R1,SMAD1,IL5,RGMB,TMEM170B,CAV2,ACTN4,SHC1,MAP1LC3A,CCR1,PRKCB,MAP2K1,MCHR1,FOSL2,CRHR1,OAS1,FCGR1A,CCL3,HNF1B,MIF,ID1,FRZB,RPS6KA4,CNTFR,LILRB1,IL12A,BCL10,TGIF2,IRF3,HEY2,USP15,IL6ST,CSF2,BTN2A2,SMAD5,STK3,CDK5R1,KCNB1,CCL5,EFNA3,UBAC2,DOK6,PRICKLE2,DLX1,HCRT,DYRK2,IL2RB,TLR3,EPHA4,SOS2,GLRA1,FLCN,SFRP1,IGF1R,TXNDC17,CSNK1E,IFT172,FERMT2,CCL17,SOCS2,HSPB1,IFNAR1,GPR17,SEMA6C,CDC42,DAPK1,IL20RB,SOCS5,IRF9,IFIH1,IL4,MYD88,IFT57,SMAD2,IDE,LILRB4,TNKS2,MIR146A,PSEN1,TULP3,PTN,HBEGF,INSYN2A,CD4,IFNB1,CAV1,TYROBP,DOK4,ADGRL3,RC3H2,CSNK1G3,FURIN,TAB1,GPBAR1,MAVS,SHC3,TNKS,CD28,ZYX,DKK3,MSTN,EFNA5,MEF2C,GPR35 |
| 3.700e-02 | -3.30 | COPRS (coordinator of PRMT5 and differentiation stimulator) | protein interactions | 55352 | 67 | 26 | 19454 | 5460 |
RPL15,RBFOX2,WDR77,SNRPN,USP39,EWSR1,HNRNPH2,RAB5A,SLU7,LSM4,RUNX1,SNRPB,MOV10,RPS2,LSM3,UBE2H,CIRBP,LSM6,CHTOP,PRMT5,RPLP1,CBFB,SMURF1,EGLN3,VIRMA,SNRPD3 |
| 3.700e-02 | -3.30 | ZNF579 (zinc finger protein 579) | protein interactions | 163033 | 67 | 26 | 19454 | 5460 |
MEST,LBR,NOTCH2,TOP3B,WDR77,RGS2,KCTD17,CDK2AP2,LRP3,CHCHD2,MRPS33,RPL27,RBM23,ILK,YAE1,KCNB1,OSGEP,CHTOP,E4F1,OSM,IFI16,DDX50,RPL10,GADD45G,PRNP,KRR1 |
| 3.700e-02 | -3.30 | MIR138-1 (microRNA 138-1) | protein interactions | 406929 | 67 | 26 | 19454 | 5460 |
KARS1,HNRNPA1,TRA2A,NONO,IGF2BP1,DDX1,CPSF1,SYNCRIP,EIF2AK2,SF3B4,MATR3,FAM98A,HNRNPL,TENT2,STRBP,RARS1,HNRNPH3,HNRNPA2B1,SF3B1,HNRNPH2,RTCB,HNRNPF,HNRNPA0,TRA2B,HNRNPK,MARS1 |
| 3.700e-02 | -3.30 | ADAM15 (ADAM metallopeptidase domain 15) | protein interactions | 8751 | 67 | 26 | 19454 | 5460 |
ST8SIA5,LMBR1L,YES1,SPPL3,MAD2L2,ESR2,SRC,MAD2L1,CUL3,DPP4,NONO,NCK1,SDF2L1,ARHGEF6,TMEM106B,SNX33,FHL3,PACSIN3,ODAM,FUT8,SP4,NUP62,CLEC2B,SFTPC,PLD3,SH3GLB1 |
| 3.700e-02 | -3.30 | FIBP (FGF1 intracellular binding protein) | protein interactions | 9158 | 67 | 26 | 19454 | 5460 |
AVPR1B,TMEM94,RPA2,RND2,SAR1B,IL13,SLC5A6,EFNB1,PCNA,CDK5,SNIP1,RPA3,BRD3,CDK12,PKNOX1,CSNK2A1,FGF1,ZCCHC10,CDK9,RHOH,MIF,DAPK1,LDLR,SYT2,CSNK2B,FGFBP1 |
| 3.700e-02 | -3.30 | TRIM3 (tripartite motif containing 3) | protein interactions | 10612 | 67 | 26 | 19454 | 5460 |
TRIM21,TRIM3,UBE2K,KRAS,UBE2D3,FXR2,GPM6A,DDX39A,ACTN4,CDKN1A,RAF1,CSNK1E,UBE2W,TP53,HGS,PDHA1,UBE2I,UBE2G2,CEP70,TNFAIP3,RPL6,CUL3,UBE2E2,EMC4,UBE2D1,BECN1 |
| 3.700e-02 | -3.30 | ARMC1 (armadillo repeat containing 1) | protein interactions | 55156 | 67 | 26 | 19454 | 5460 |
GNAO1,SEC23A,CSK,RALB,SLC25A46,PYCR1,EPS8,GNG2,GALE,UFD1,CRMP1,HTRA2,RAB3A,RPA3,HSPA8,GPM6B,BAG2,CNTN1,CAMKV,GPM6A,HNRNPDL,NCALD,SNCB,STXBP1,RPA2,TBC1D13 |
| 3.700e-02 | -3.30 | CRIPTO (cripto, EGF-CFC family member) | protein interactions | 6997 | 67 | 26 | 19454 | 5460 |
AP2S1,ACVR1,BMPR2,NEU1,RANBP10,ACVR1B,TGFBR2,FARSA,MKLN1,RMND5B,BMPR1A,GID4,MAEA,GID8,YPEL5,ARMC8,TCEAL9,ZMYND19,LRFN3,ACVR1C,LRIF1,PCSK9,IL18,ADAM21,GANAB,AIP |
| 3.700e-02 | -3.30 | EFHD1 (EF-hand domain family member D1) | protein interactions | 80303 | 67 | 26 | 19454 | 5460 |
S100A8,ACOX1,CTTN,SCG5,G2E3,RAB39B,DUSP10,ESR2,HNRNPL,NDNF,RPL35A,ACTB,MPP1,USP14,MYC,NRP1,UBE2H,PSEN1,FOXP2,HSPA5,TRIM37,TOP3B,PGRMC1,TFRC,CAPZA2,OXNAD1 |
| 3.700e-02 | -3.30 | LYPLA1 (lysophospholipase 1) | protein interactions | 10434 | 67 | 26 | 19454 | 5460 |
SH3BGRL,TXNDC12,CCNF,AIFM1,PCCB,AK3,LAMTOR2,MTRF1,OXCT1,HSCB,TRIM11,PRDX6,ARFIP1,COX17,COA4,PTRHD1,CCR1,AQP3,ACADSB,CAPZA2,GTF2E2,FCF1,CNPY3,CDC42,RAF1,LYPLA1 |
| 3.717e-02 | -3.29 | cellular response to nutrient levels | biological process | GO:0031669 | 231 | 81 | 18204 | 5365 |
SEC13,SESN3,VDR,CTSK,GLUL,SFRP1,FLCN,IGF1R,LAMP2,PRKAB1,BGLAP,KICS2,EP300,ALB,KCNB1,SLC2A1,MDM2,YWHAG,RRAGA,UCP2,HNRNPA1,TP53,FOXA3,GABARAP,ATF3,FOLR2,RNF167,PPARA,TFEB,CREBBP,WDR45,ATF4,LEP,FAM107A,COMT,RALB,MIOS,KLF10,MAP1LC3B,HSPA8,BMPR2,RNF152,PMAIP1,EIF2S1,GABARAPL1,SLC38A2,FBXO22,MAP1LC3A,DAP,PRKAG1,FOLR1,FOS,NFE2L2,SAR1B,SH3GLB1,FGF23,PCSK9,CDKN1A,RRAGB,BECN1,SP1,IFI16,PICK1,STK26,CSNK1A1,CARTPT,LAMTOR1,PPM1D,ATG7,XBP1,GABARAPL2,HSPA5,STK24,IMPACT,EIF2AK2,FAS,SUV39H1,SESN2,SLC38A3,RHEB,YWHAZ |
| 3.721e-02 | -3.29 | TMEM14C (transmembrane protein 14C) | protein interactions | 51522 | 64 | 25 | 19454 | 5460 |
CRELD1,SHOC2,TMEM14B,LMNA,RPA2,TMEM31,NDUFS3,ELOVL7,RIGI,GJB1,SPCS2,TMX2,VSIR,SFXN1,ZDHHC15,STX1A,PDZK1IP1,NCR3LG1,AGR2,CREB3,SH3BGRL,COMT,RCHY1,CYB5R3,SSMEM1 |
| 3.721e-02 | -3.29 | ARHGAP11A (Rho GTPase activating protein 11A) | protein interactions | 9824 | 64 | 25 | 19454 | 5460 |
CAPZA2,DDX42,E2F4,CSNK1E,SF3A1,CD2AP,PPP1CB,HSPE1,H3C1,PPP1R12A,PALM2AKAP2,PCNA,RHOB,CKB,VMP1,RCL1,SFN,MYC,CPSF2,TPM3,THOC1,APEX1,PSMB6,CPSF1,WDR82 |
| 3.721e-02 | -3.29 | ABHD14A (abhydrolase domain containing 14A) | protein interactions | 25864 | 64 | 25 | 19454 | 5460 |
PPP5C,SPPL3,NRSN1,GGT7,CD1E,CD63,ZMPSTE24,RUNX1,TRIM32,GABRG2,FKRP,GINS3,PAFAH1B2,SYVN1,NDUFA4,LRP10,CHRNB2,FAM8A1,TMEM59L,CTSA,BZW2,UBAC2,GPR35,TMEM59,TUBA1A |
| 3.721e-02 | -3.29 | MPO (myeloperoxidase) | protein interactions | 4353 | 52 | 21 | 19454 | 5460 |
PTP4A2,CYP3A43,STX17,CCR1,STK11,HSPB1,AGPAT1,MYC,PRKX,CCDC47,TIMM10,RNF40,HNRNPK,ESR2,RAD21,PML,MAEA,S100A8,EGFL8,ERO1A,ALB |
| 3.721e-02 | -3.29 | NAP1L5 (nucleosome assembly protein 1 like 5) | protein interactions | 266812 | 52 | 21 | 19454 | 5460 |
MBLAC2,TRA2A,BAG3,STK38L,NOP16,RPL6,ATF4,RPS2,OSGEP,RRP7A,MAGEH1,H2BC11,CLPB,CMBL,SKA1,BAP1,DFFA,TSPYL4,TMEM97,SNRPB2,PTN |
| 3.721e-02 | -3.29 | SERPINE1 (serpin family E member 1) | protein interactions | 5054 | 52 | 21 | 19454 | 5460 |
PLG,TMEM237,ARF1,ERP29,SGTA,PSMA3,PSMB1,GANAB,HSD17B11,QSER1,HSP90B1,LMNA,F2,ANP32A,RAF1,CD14,KCND3,MYC,CFTR,SOX2,ACTN4 |
| 3.721e-02 | -3.29 | POLR1F (RNA polymerase I subunit F) | protein interactions | 221830 | 52 | 21 | 19454 | 5460 |
STAU1,POLR1H,NCBP2,POLR2L,POLR2F,FBXW11,NR2E1,MOB3C,NUPR1,POLR1B,RRN3,ATG16L1,MYC,MPG,CFTR,PPP1CC,POLR1D,ATG7,FIG4,TAF1D,YWHAH |
| 3.721e-02 | -3.29 | FGF2 (fibroblast growth factor 2) | protein interactions | 2247 | 52 | 21 | 19454 | 5460 |
S100B,SDC4,COMT,FGFBP1,CSNK2B,TES,TAX1BP1,IFI16,CREBBP,RPL6,MAP1LC3B,CXCL13,CSNK2A1,GPC4,API5,CRYAB,TUBG1,SDC2,AGER,FGFR1,NRP1 |
| 3.721e-02 | -3.29 | Snw1 (SNW domain containing 1) | protein interactions | 66354 | 52 | 21 | 19454 | 5460 |
HOMER1,CDC5L,G6PD,CWC15,DHX15,CDC40,SNRPD3,SNRNP40,RBM22,SNRPD1,SNRPD2,SLU7,RSRC1,HOMER3,PRSS23,SNRPE,ZNHIT3,TMEM165,ESS2,PRPF19,AKR7A2 |
| 3.721e-02 | -3.29 | SH2B2 (SH2B adaptor protein 2) | protein interactions | 10603 | 52 | 21 | 19454 | 5460 |
LMO3,TOP3B,SYK,AKT1,WDR83,USP2,CBL,MET,MAGEH1,LAMTOR1,VPS33A,TLNRD1,SHC1,RAB6B,CLK1,JAK1,NTRK2,MTDH,INPPL1,JAK2,KIT |
| 3.721e-02 | -3.29 | FBXO30 (F-box protein 30) | protein interactions | 84085 | 52 | 21 | 19454 | 5460 |
FBXO34,UBE2M,ACVR1,MYO6,RPA2,VPS33A,SMAD4,SMAD1,BCL7C,CUL3,RAF1,MOV10,SKP1,SMURF1,EGLN3,ACTB,DYNLL1,MYO1B,ACTA2,PSME1,RPA3 |
| 3.721e-02 | -3.29 | ABCA1 (ATP binding cassette subfamily A member 1) | protein interactions | 19 | 52 | 21 | 19454 | 5460 |
LIN7C,SDHB,COPS2,AOX1,ATXN10,NR1H2,PDLIM3,FLOT1,UGP2,DLG3,LIN7B,MYC,CDC42,COPS5,CSNK2A1,TIAM1,PALS2,SNTA1,HGS,PDLIM4,STX12 |
| 3.726e-02 | -3.29 | SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2) | protein interactions | 6603 | 174 | 60 | 19454 | 5460 |
SS18,MBD3,STAU1,NUP50,DDIT3,FOS,SMARCD3,RPA3,KLF4,ELF5,PAX9,RPA2,ELP3,ACTL6A,ESR2,RBBP4,ACTB,MACROH2A1,PRMT5,SMAD2,BRCA1,AR,SAMHD1,SMARCE1,IRF1,CUL3,HNRNPC,MYC,MDC1,PAX6,KPNA2,FAM168A,HAPSTR1,TOP2B,BCL7B,SNIP1,SMARCB1,MTA2,RBPJ,EZH2,SOX9,SOX2,NUP153,H2AX,TP53,RAF1,PPIA,ARF6,BRD9,SIN3A,PTPN1,H2AZ1,LHX2,BRD3,KPNA1,HNRNPD,MED4,BCL7C,WWP2,BAZ1B |
| 3.734e-02 | -3.29 | Androgen receptor signaling pathway | WikiPathways | WP138 | 90 | 41 | 5310 | 1910 |
PTEN,SUMO1,JUN,CREBBP,RHOB,PIK3R2,SRC,AR,CDKN1A,SP1,EP300,FKBP4,KLK3,CTNNB1,UBE2I,STUB1,PIAS1,SIN3A,KDM1A,SMAD3,TGFB1I1,CAV1,UBE3A,ROCK2,AKT1,ROCK1,RB1,CREB1,BRCA1,PIK3R1,PRDX1,PAK6,DSTN,SMAD4,CCND1,RAN,RNF14,CDC42,SMARCE1,MDM2,CALR |
| 3.734e-02 | -3.29 | MIB2 (MIB E3 ubiquitin protein ligase 2) | protein interactions | 142678 | 61 | 24 | 19454 | 5460 |
PLAAT3,TBK1,PI15,TOP3B,CCT5,TNRC6C,IKZF5,TNF,XRCC5,ZC3H7A,MAVS,P2RY1,BCL10,UBE2D1,CCT2,F9,CUL3,CCT7,APEX1,SRPK2,SRP14,CD274,UBE2N,TMEM74 |
| 3.734e-02 | -3.29 | ATF1 (activating transcription factor 1) | protein interactions | 466 | 61 | 24 | 19454 | 5460 |
ELF1,EDF1,JUN,GABPB1,CAMK1,RBPJ,MAPKAPK3,MIA2,HSPA8,CAMK2G,NFIL3,CREBBP,HNF1B,ATF1,CSGALNACT2,CSNK2A1,BRCA1,RPS6KA4,ARL2BP,FOSL2,CREB1,CSNK2B,GABPA,JUNB |
| 3.734e-02 | -3.29 | VPS8 (VPS8 subunit of CORVET complex) | protein interactions | 23355 | 61 | 24 | 19454 | 5460 |
STX7,VPS16,EFNB1,RAB9A,RAB5A,RUSF1,CYB5B,SIGLECL1,VPS33A,RAB4A,VPS18,HCST,FAXC,COMTD1,APEX1,VIRMA,SMAD9,LAMTOR1,LAMP2,ATG9A,RAB11A,SUB1,GPR17,RAB5C |
| 3.734e-02 | -3.29 | TSPAN10 (tetraspanin 10) | protein interactions | 83882 | 61 | 24 | 19454 | 5460 |
RAB9A,MTCH2,ADIPOR1,TMEM205,ALG11,GOLGA5,GPD2,CSNK1G3,OXSR1,SLC1A1,GNPAT,RETREG3,GJA1,SC5D,LHFPL1,SPPL3,NRSN2,HNRNPL,UQCRH,LAMP2,VEZT,FAM241A,TMEM11,FITM2 |
| 3.734e-02 | -3.29 | MAN2B1 (mannosidase alpha class 2B member 1) | protein interactions | 4125 | 61 | 24 | 19454 | 5460 |
MOV10,ATG7,IDO1,GGH,SDF2L1,SMAD9,OAT,ELSPBP1,NKX3-1,CHID1,DNAJB9,SNX2,FIBIN,TOP3B,PI15,CD14,SPR,MGARP,RPA2,NCR3,DTD1,RPA3,RIGI,SKP1 |
| 3.734e-02 | -3.29 | Cdc26 (cell division cycle 26) | protein interactions | 66440 | 61 | 24 | 19454 | 5460 |
ANAPC2,GNPTG,BUB3,TTC9C,FZR1,TMPO,CDC20,CDC16,PRDX1,ANAPC15,MECP2,CAMSAP2,ANAPC4,CDC23,HIRA,BCL7B,ANAPC16,RBCK1,MREG,TOMM22,PRDX3,NEK2,ANAPC13,PITPNA |
| 3.734e-02 | -3.29 | PTPN18 (protein tyrosine phosphatase non-receptor type 18) | protein interactions | 26469 | 61 | 24 | 19454 | 5460 |
NDUFS3,MLLT11,HSPD1,MAIP1,HSPA8,TMX3,BAG2,RIGI,MOV10,CSK,STOML2,ATP5F1A,ARHGAP5,HAX1,DNAJC7,CDIPT,GAB1,AIFM1,ARF1,STUB1,AIP,CTSB,HNRNPL,SRC |
| 3.734e-02 | -3.29 | PCDHGA5 (protocadherin gamma subfamily A, 5) | protein interactions | 56110 | 61 | 24 | 19454 | 5460 |
NXPE3,ABCB9,MT2A,CYB5R1,GINM1,TMEM39A,ADCY3,EPHX1,ZNHIT6,ITGA6,SRC,LRIF1,OSBP,DAG1,MBLAC2,DHRS7,TMEM199,KLHL9,RETSAT,RPL23,BTN2A2,AREL1,SMPD2,SNX14 |
| 3.734e-02 | -3.29 | KDM5A (lysine demethylase 5A) | protein interactions | 5927 | 61 | 24 | 19454 | 5460 |
RAF1,VDR,KLF12,KLF3,MXD1,EZH2,RBPJ,STAU1,RBBP7,CHCHD2,TM9SF4,MORF4L1,LMO2,PPP1CC,YWHAH,BGLAP,TUBA1B,PHF12,RB1,GATAD1,EED,RBBP4,VIRMA,ESR2 |
| 3.734e-02 | -3.29 | RNF170 (ring finger protein 170) | protein interactions | 81790 | 61 | 24 | 19454 | 5460 |
TLR3,P2RY12,IDH2,TM9SF4,GPR17,CCR6,TMBIM6,ERLIN2,ATAD1,DNAJC30,LPAR1,TMEM97,UBE2L3,ERLIN1,TMUB1,DUSP3,PLPP6,LMBR1L,PSMA6,RETREG3,HACD1,SGTA,TMX3,COPS2 |
| 3.736e-02 | -3.29 | MYLIP (myosin regulatory light chain interacting protein) | protein interactions | 29116 | 55 | 22 | 19454 | 5460 |
DDIT4L,MYLIP,LNX2,MYL12B,SDCBP,PAX9,ZBTB42,VLDLR,ZBTB16,KRAS,UBE2D3,KDM1A,USP2,AR,UBE2D1,ATG3,SCNM1,UBE2N,ZBTB18,MTAP,LDLR,SRPK2 |
| 3.736e-02 | -3.29 | CDKN3 (cyclin dependent kinase inhibitor 3) | protein interactions | 1033 | 55 | 22 | 19454 | 5460 |
BRCA1,HAX1,PTPN5,CDKN3,DIS3L,ATXN10,CD47,SEC63,ROCK1,HDHD5,CDK1,PSMC3,RAD23B,PSMC4,ROCK2,MSH6,UNC45A,PSMC1,PSMD12,PPP1R12A,DLAT,CLPB |
| 3.736e-02 | -3.29 | FAN1 (FANCD2 and FANCI associated nuclease 1) | protein interactions | 22909 | 55 | 22 | 19454 | 5460 |
SUB1,NOP16,YWHAZ,CD99L2,APEX1,CAVIN2,PLEKHA8,DDX39A,PPP2R1A,AKR7A2,HEXA,SUPT5H,CCR1,NCOA5,NUDT16,ANXA7,RBM34,PCNA,RFC4,FANCG,RFC3,MLH3 |
| 3.736e-02 | -3.29 | H4C13 (H4 clustered histone 13) | protein interactions | 8368 | 55 | 22 | 19454 | 5460 |
TRIM24,HIRA,H2AZ1,PARP2,CBX5,TMPO,MCM6,SSRP1,RAD21,RBBP7,CAND1,RBBP4,SHPRH,ASF1A,COPS5,H2AX,MCM4,CUL3,CUL2,BRD3,RBBP8,PPTC7 |
| 3.736e-02 | -3.29 | ASIC1 (acid sensing ion channel subunit 1) | protein interactions | 41 | 55 | 22 | 19454 | 5460 |
SDF2L1,ASIC2,MBLAC2,HMOX2,RAB2A,MGST2,RAB11A,DUOXA2,ARF6,ASIC1,ODR4,ST8SIA5,DPEP1,STOM,SFTPC,GP9,JUN,B3GALT4,RIGI,PICK1,SEC11A,EP300 |
| 3.736e-02 | -3.29 | CYP24A1 (cytochrome P450 family 24 subfamily A member 1) | protein interactions | 1591 | 55 | 22 | 19454 | 5460 |
ABHD10,MRPS7,CDC20,MALSU1,RASL10B,FZR1,FAHD1,HINT2,HSD17B8,AMACR,HDHD3,SLC25A10,TYROBP,NDUFS6,AQP3,ACAA2,SMAD4,TAFAZZIN,QRSL1,CBR4,ETFBKMT,CSK |
| 3.736e-02 | -3.29 | RHOT1 (ras homolog family member T1) | protein interactions | 55288 | 55 | 22 | 19454 | 5460 |
HSCB,PCSK9,CDK20,APEX1,FTL,CCNF,PHB1,NUBP2,AKAP1,TRAK2,RPA2,PPTC7,KLK5,NRP1,FURIN,ILK,MTCH2,SOX2,MGARP,CFTR,ERLIN2,DDRGK1 |
| 3.736e-02 | -3.29 | MAP7D2 (MAP7 domain containing 2) | protein interactions | 256714 | 55 | 22 | 19454 | 5460 |
CAMSAP2,MAPRE1,BICD2,NDC80,EGLN3,EIF2B5,TRIM27,TRIM36,RPA2,PNMA2,TUBA1A,KIF2A,INSIG2,TRIM52,P4HA2,EFNB1,FHL3,UBE3A,OLFML3,LCA5,RPA3,STX8 |
| 3.736e-02 | -3.29 | CCDC88C (coiled-coil domain containing 88C) | protein interactions | 440193 | 55 | 22 | 19454 | 5460 |
SFN,TOP3B,ALDH1L1,CTNNB1,BAG3,FBXO7,YWHAG,YWHAH,YWHAZ,RHOB,GNAI3,YWHAB,UBE2H,SIKE1,CTNNA1,SQSTM1,TRIM11,RAB5A,FZD6,RIGI,VIRMA,SMURF1 |
| 3.736e-02 | -3.29 | AFAP1 (actin filament associated protein 1) | protein interactions | 60312 | 55 | 22 | 19454 | 5460 |
ESR2,VIRMA,SRC,TOLLIP,PRKCE,GSK3A,CSNK2B,PRKCB,TES,TNFRSF1B,PRKCA,NUPR1,VMP1,MAPRE1,BRCA1,CAPZA2,FGFR1,PPP1CB,PPIB,CDC42,AKT3,MYC |
| 3.740e-02 | -3.29 | ZBTB47 (zinc finger and BTB domain containing 47) | protein interactions | 92999 | 142 | 50 | 19454 | 5460 |
MPHOSPH10,ZCCHC9,POU5F1,MRPS26,MOV10,PNMA3,ISG20L2,SURF6,NOP9,MRPS23,DKC1,HP1BP3,RPLP2,RBM34,GLE1,RPL18,MRPL51,MRPL47,MAK16,IMP4,PAK1IP1,H1-6,RPS13,SRSF12,NKRF,SRSF8,BRCA1,FTSJ3,FYTTD1,NSA2,NCKIPSD,RPL7A,RPF2,CEP70,ZSCAN25,ZNF668,RPL7L1,ZCCHC7,ZNF189,ZNF22,ZNF770,RPL26L1,RPLP0,ZNF574,STAU1,RPS15,BRIX1,MRPS7,NGRN,CCDC106 |
| 3.740e-02 | -3.29 | ASB18 (ankyrin repeat and SOCS box containing 18) | protein interactions | 401036 | 26 | 12 | 19454 | 5460 |
NME1,PRKAG1,RPL15,ELOC,NONO,THRAP3,TFG,PRPS1,ERH,SLC25A5,AKR1B1,PRPSAP1 |
| 3.740e-02 | -3.29 | CCDC82 (coiled-coil domain containing 82) | protein interactions | 79780 | 26 | 12 | 19454 | 5460 |
TF,TRIM29,SPPL3,SGF29,SSRP1,LY6G6C,ALB,CSNK2B,NETO2,COPS7A,CSNK2A1,DDX39A |
| 3.740e-02 | -3.29 | KLHL33 (kelch like family member 33) | protein interactions | 123103 | 26 | 12 | 19454 | 5460 |
CCT7,PDCL,TCP1,SPPL3,CCT2,BAG3,HSPA8,CCT5,SAV1,CCT8,STUB1,HSPD1 |
| 3.740e-02 | -3.29 | ARHGEF25 (Rho guanine nucleotide exchange factor 25) | protein interactions | 115557 | 26 | 12 | 19454 | 5460 |
LMO3,SMARCE1,CDC42,HBB,NEFL,CCDC86,RTRAF,FUBP3,GABRB2,RHOU,PPP1R12A,FLOT1 |
| 3.740e-02 | -3.29 | FAM32A (family with sequence similarity 32 member A) | protein interactions | 26017 | 26 | 12 | 19454 | 5460 |
APEX1,NSFL1C,FBXW7,RPS24,MRPL53,FOXP1,UBE2H,CCDC22,CFTR,ATG16L1,MYC,RAF1 |
| 3.740e-02 | -3.29 | STX19 (syntaxin 19) | protein interactions | 415117 | 26 | 12 | 19454 | 5460 |
SUV39H1,STXBP1,TBK1,SUFU,VAMP2,SNAP23,VAMP3,ZNF330,SCNM1,VAMP8,KDM1A,SNAP25 |
| 3.740e-02 | -3.29 | KHK (ketohexokinase) | protein interactions | 3795 | 26 | 12 | 19454 | 5460 |
SPG21,SNRPB,COPS5,CD2BP2,LHX2,AP2S1,DEDD,LYZ,CDK5RAP3,LCN1,APPBP2,UGP2 |
| 3.740e-02 | -3.29 | SMDT1 (single-pass membrane protein with aspartate rich tail 1) | protein interactions | 91689 | 26 | 12 | 19454 | 5460 |
COX6C,CYFIP2,EIF2B2,EIF2B3,PDCD1,BZW2,EIF2B5,COX7B,MOV10,HDHD5,COX4I1,IL2RA |
| 3.740e-02 | -3.29 | AP1AR (adaptor related protein complex 1 associated regulatory protein) | protein interactions | 55435 | 26 | 12 | 19454 | 5460 |
RIGI,STX7,STX6,HRAS,DUSP9,RAB9A,RAB5A,RAB4A,AP1S2,ATG16L1,ATG9A,LAMP2 |
| 3.740e-02 | -3.29 | F3 (coagulation factor III, tissue factor) | protein interactions | 2152 | 26 | 12 | 19454 | 5460 |
TNFSF8,PLG,DAD1,MDM2,STUB1,F10,RAB13,EPHA2,STX12,SCN3B,TM9SF4,F7 |
| 3.740e-02 | -3.29 | UNC5C (unc-5 netrin receptor C) | protein interactions | 8633 | 26 | 12 | 19454 | 5460 |
RHOB,RAB11A,ATG9A,DPP4,CAV1,APEX1,STX6,KRAS,DAPK1,RAB5A,GJA1,RAB35 |
| 3.740e-02 | -3.29 | TRMT2B (tRNA methyltransferase 2 homolog B) | protein interactions | 79979 | 26 | 12 | 19454 | 5460 |
SSBP1,HSPD1,FBLN5,EXD2,RABGGTB,AKT1,PFDN5,PTPN11,MRPL12,RHOG,PPTC7,RNF181 |
| 3.740e-02 | -3.29 | AGGF1 (angiogenic factor with G-patch and FHA domains 1) | protein interactions | 55109 | 58 | 23 | 19454 | 5460 |
LMNB1,FTSJ3,COP1,STK11,KXD1,MOV10,CCDC85B,PRNP,DYNLL1,SNRNP40,DHX15,MDM2,NABP1,CCDC71,AGGF1,ZC4H2,TP53,TNFSF12,COIL,SIKE1,SLU7,YAF2,IDH1 |
| 3.740e-02 | -3.29 | KDM3A (lysine demethylase 3A) | protein interactions | 55818 | 58 | 23 | 19454 | 5460 |
PML,ARPP19,PRMT5,RTRAF,NUP50,POLR2F,TCEAL1,IRF2BP1,HUWE1,EIF4H,SNRNP40,RIGI,BTG3,VIRMA,MYC,OST4,GFUS,CUL3,AR,PPP1CC,CBX3,STAT6,UBE2H |
| 3.740e-02 | -3.29 | GTPBP2 (GTP binding protein 2) | protein interactions | 54676 | 58 | 23 | 19454 | 5460 |
SUV39H1,CUL3,PLEKHO1,PRMT6,RAB11A,GTPBP2,STK11,SNRNP70,PSMB1,LDLR,PRMT5,RPL10,PLEKHF2,RBMS2,TP53,CHRM3,PICK1,SAR1B,RIGI,RPL4,GPIHBP1,DCP2,KDM1A |
| 3.740e-02 | -3.29 | CILK1 (ciliogenesis associated kinase 1) | protein interactions | 22858 | 58 | 23 | 19454 | 5460 |
CDK20,SPTAN1,CAMK2G,HNRNPL,HSP90AB1,MNAT1,CPSF1,IFT172,CDC7,SLC35A1,CENPL,CDK1,LSM14B,HSP90AA1,HEXIM1,CD247,TP53,CKS1B,TMEM45A,SMAD1,DDX39A,PSMD1,FBXO7 |
| 3.740e-02 | -3.29 | MAPKAPK5 (MAPK activated protein kinase 5) | protein interactions | 8550 | 58 | 23 | 19454 | 5460 |
HMGB1,EIF4E,HSPD1,BCL7B,HSPB2,TP53,MAPKAPK5,CSNK1E,TOP3B,JUN,DDX39A,TAB1,ZNF576,SRPK2,GYS1,UQCRC2,TRAF7,YWHAZ,UBE2H,HSPB1,MAPK4,CSK,YWHAG |
| 3.740e-02 | -3.29 | MYDGF (myeloid derived growth factor) | protein interactions | 56005 | 58 | 23 | 19454 | 5460 |
HSPA5,PEBP1,IGF1R,HSPA8,ACOT13,NUDT19,FKBP1A,SOD2,E2F4,NCALD,HPCAL1,PGM1,MDM2,ESD,FABP5,SGTA,GATD3,CMBL,TMOD2,TST,DPP4,MOV10,HPCA |
| 3.740e-02 | -3.29 | GOLGA7 (golgin A7) | protein interactions | 51125 | 58 | 23 | 19454 | 5460 |
KCNIP2,RHOG,NAA50,PPP1CC,TOMM40,KCNIP3,APEX1,PTPN1,MACROH2A1,SLC1A1,NUPR1,TSPAN3,NCALD,RND2,CDC42,VRK1,SSRP1,RAD21,RDH11,CLDND1,RAB5A,EMG1,SEC11A |
| 3.740e-02 | -3.29 | SMIM1 (small integral membrane protein 1 (Vel blood group)) | protein interactions | 388588 | 58 | 23 | 19454 | 5460 |
ZDHHC15,STX1A,TMEM31,CYB561,FCER1G,RELL2,HACD2,MFSD6,NDUFAF2,ASZ1,TM4SF19,FAM174A,SCN3B,TMEM45B,REEP4,FNDC9,RETREG3,ICAM3,TMX2,JAGN1,LRP10,COMT,ELOVL4 |
| 3.751e-02 | -3.28 | CAMSAP2 (calmodulin regulated spectrin associated protein family member 2) | protein interactions | 23271 | 158 | 55 | 19454 | 5460 |
GSK3A,UBE2I,CCNF,ATXN1L,ESR2,VIRMA,DYRK1A,TUBB,MAP3K21,PPP1CC,SYCE3,CREBBP,SFN,HNRNPC,OAZ1,SETD7,MAPRE1,BICD2,YWHAZ,CCDC22,DDX5,DNAJC3,RTKN,SIPA1L1,BORCS6,INPP5E,AGAP1,TRIM36,KRT8,EIF4E2,CGGBP1,EGLN3,TRMT61A,SLAIN2,KCTD3,MAPRE2,EIF2B5,YWHAH,YWHAG,XPO1,SNAP91,MAP1S,NDC80,SSX2IP,YWHAB,TDRD7,TIAM1,TESK2,SRSF12,TRIM37,TUBA1A,KIF2A,KIF1C,TUBB4B,SKA3 |
| 3.755e-02 | -3.28 | response to interferon-beta | biological process | GO:0035456 | 33 | 15 | 18204 | 5365 |
IFNB1,UBE2G2,HTRA2,IRF1,UBE2K,STAT1,TLR3,XAF1,BST2,CAPN2,IFI16,TRIM6,OAS1,IFNAR1,PLSCR1 |
| 3.755e-02 | -3.28 | negative regulation of calcium ion transmembrane transporter activity | biological process | GO:1901020 | 33 | 15 | 18204 | 5365 |
FKBP1A,CLIC2,PLN,TLR9,MIR200C,MIR208A,GSTO1,GSTM2,MIR208B,FKBP1B,DRD3,SRI,CRHR1,ATP1A2,GPR35 |
| 3.755e-02 | -3.28 | negative regulation of dephosphorylation | biological process | GO:0035305 | 33 | 15 | 18204 | 5365 |
PPP1R8,FKBP1B,SWAP70,ROCK1,PPP1R1B,MIR146A,ARPP19,TNF,FKBP1A,YWHAB,LGALS3,ROCK2,IKBKB,CHP1,INPP5K |
| 3.755e-02 | -3.28 | positive regulation of phospholipase C activity | biological process | GO:0010863 | 33 | 15 | 18204 | 5365 |
FGFR1,LPAR1,ADRA1A,HTR2A,S1PR4,KIT,PHB2,AVPR1B,LPAR2,PLCB2,GNAQ,HRAS,ITK,CD86,PHB1 |
| 3.755e-02 | -3.28 | pigment cell differentiation | biological process | GO:0050931 | 33 | 15 | 18204 | 5365 |
CITED1,ADAMTS20,RAB27A,SOD2,RAB32,BLOC1S5,MEF2C,MREG,MITF,BLOC1S3,KIT,CD63,AP1M1,OR51E2,USP13 |
| 3.755e-02 | -3.28 | T cell migration | biological process | GO:0072678 | 33 | 15 | 18204 | 5365 |
SLC12A2,ICAM1,CCL2,CCL3,F11R,CXCL10,SELENOK,CRKL,MSN,PIK3CG,GPR15,CCL20,CXCL11,CCR2,CCR6 |
| 3.756e-02 | -3.28 | Protein folding | REACTOME pathways | R-HSA-391251 | 105 | 42 | 10285 | 3229 |
GNB3,GNGT2,CSNK2B,GNAZ,TBCE,RGS6,PFDN2,TUBA1A,GNAI2,PDCL,ACTB,GNAO1,CCT2,GNG10,GNG5,GNG11,FBXW4,GNAI3,GNG3,CCT8,GNG13,PFDN6,TUBA1B,PFDN4,FBXL3,CCT7,MIR197,GNG2,FBXW7,TUBB4B,GNG12,TCP1,HDAC3,WRAP53,CSNK2A1,PFDN1,GNB4,GNG7,CCT5,PFDN5,TP53,GNB1 |
| 3.757e-02 | -3.28 | positive regulation of pattern recognition receptor signaling pathway | biological process | GO:0062208 | 67 | 27 | 18204 | 5365 |
TICAM2,MYD88,TRIM3,CD14,RTN4,PTPN22,HMGB1,ZNRF1,TLR9,NINJ1,TLR4,FLOT1,PELI1,TLR6,USP15,IFI35,TIRAP,TRIM15,TAB1,MAVS,CAV1,TASL,TLR1,NEK7,ATAT1,CD36,RSAD2 |
| 3.757e-02 | -3.28 | ILKAP (ILK associated serine/threonine phosphatase) | protein interactions | 80895 | 101 | 37 | 19454 | 5460 |
PPM1G,RPA3,LUM,PRPF4,PML,MYO1B,IGF1R,UFL1,KIT,STK38,SNRNP27,MAEL,LMNA,RPA2,CBX3,PAK2,NDUFS6,PPID,METTL14,RPS11,CERK,HGS,PTK7,CFAP298,MATR3,RAB14,STAT5A,AASDHPPT,CDK9,CEP19,CSK,FBXO7,DDRGK1,SMAD4,EPHA2,UBE2H,ILK |
| 3.757e-02 | -3.28 | RRAS2 (RAS related 2) | protein interactions | 22800 | 101 | 37 | 19454 | 5460 |
ACVR1,FOXS1,PGGT1B,RAF1,FNTB,RGL1,TRAF2,RND2,CDC42,KRAS,BAP1,PMAIP1,RABGGTB,RABAC1,RHOB,YWHAZ,AGR2,SMAD4,RHOG,TSNAX,YWHAB,TRAPPC4,BMPR1B,CREB3,MYC,PIK3R1,HDAC6,YWHAH,YWHAG,RHOJ,RHOH,ESR2,SMAD3,PTPN1,CCNF,RAC2,TRAF7 |
| 3.757e-02 | -3.28 | GPRC5C (G protein-coupled receptor class C group 5 member C) | protein interactions | 55890 | 101 | 37 | 19454 | 5460 |
LPAR2,APPBP2,HSPA8,BSCL2,TACR1,MIA2,RHOU,TSPAN15,STX7,KRAS,TNFSF8,SLC7A1,LPAR1,FAM8A1,RAB4A,GPR35,SYNGR1,GPR173,SNX17,LMBR1L,SCAMP2,CLRN2,DUOXA2,ESR2,B4GAT1,ARF6,SYNE4,TNFSF18,LAMP3,GOLPH3L,LAMP2,RAB2A,RAB11A,FMO1,P2RY1,RHOG,LAMTOR1 |
| 3.759e-02 | -3.28 | immune response-activating cell surface receptor signaling pathway | biological process | GO:0002429 | 228 | 80 | 18204 | 5365 |
EIF2B3,YES1,LY96,SPG21,BAX,KLRC2,PIK3AP1,CLEC7A,CSK,CACNB3,FCN2,FGR,FCER1G,SPPL3,NFKBIA,EP300,PIK3CA,STOML2,STK11,PDE4B,CREBBP,HRAS,THY1,TLR4,BTN2A2,NCR3,MICB,IRF3,BCL10,SRC,FOXP3,SYK,PLPP4,CD79B,PTPN22,MBL2,EIF2B2,ITK,MEF2C,MOG,OAS1,FOSL2,PRKCB,NFKB1,CACNB4,PRKCE,CD28,IKBKB,RBCK1,CLEC6A,RC3H2,TIRAP,NMI,VAV2,TICAM1,TYROBP,KLRD1,UBE2N,TBK1,PSEN1,LAT2,CTLA4,CD247,CRKL,TMEM126A,EIF2B5,LILRA2,TLR5,PAK2,LCP2,CD14,SLA2,TLR2,MYD88,TRAF6,IRAK4,TICAM2,CD38,CD2AP,CD3G |
| 3.760e-02 | -3.28 | Cyt_P450_CS | interpro domains | IPR017972 | 53 | 22 | 18521 | 5414 |
CYP2C18,CYP26A1,CYP2R1,CYP11B1,CYP2F1,CYP27A1,CYP7A1,CYP4V2,CYP1B1,CYP3A5,CYP27B1,CYP17A1,CYP4F8,CYP3A43,CYP21A2,CYP2D6,CYP4F12,CYP2C9,CYP4F22,CYP11B2,CYP2C8,CYP1A1 |
| 3.760e-02 | -3.28 | Tumour_necrosis_fac-like_dom | interpro domains | IPR008983 | 53 | 22 | 18521 | 5414 |
C1QC,TNFSF8,C1QTNF1,C1QL3,TNFSF10,TNFSF13,TNFSF12,TNF,LTB,CBLN1,TNFSF15,ADIPOQ,LTA,CBLN3,CBLN2,EMILIN1,C1QL2,C1QL1,CD40LG,CBLN4,FASLG,TNFSF18 |
| 3.767e-02 | -3.28 | CUX1 (cut like homeobox 1) | protein interactions | 1523 | 187 | 64 | 19454 | 5460 |
CPSF1,IRF2,ZNF330,TNFRSF9,ANAPC2,RBBP4,VIRMA,ESR2,B4GAT1,APEX1,HNF1B,CREBBP,CCNB1,BTF3,AR,FOXD3,CXCR4,TSPAN15,RAB30,NUP50,KDM1A,HMGB1,WDR83,KCND3,NUP62,BET1,CA12,CDK7,CDK1,GOLGA5,GP9,KLF4,RB1,KRT8,RAB1B,HNRNPL,SUMO2,TNFSF18,LRRC61,STX6,CAV1,KXD1,SPATS2L,CTNNB1,RB1CC1,NDUFB8,LHX2,FOXP1,RAB1A,LPAR2,PCNA,H3C1,SATB1,ASF1A,CYTH2,PAX6,SACM1L,MAX,SOX2,TMEM59,SOX9,CBX3,RBPJ,SSBP3 |
| 3.769e-02 | -3.28 | NA_NEUROTRAN_SYMP_2 | prosite domains | PS00754 | 18 | 9 | 12186 | 3388 |
SLC6A2,SLC6A1,SLC6A4,SLC6A3,SLC6A6,SLC6A7,SLC6A8,SLC6A12,SLC6A11 |
| 3.769e-02 | -3.28 | CRIB | prosite domains | PS50108 | 18 | 9 | 12186 | 3388 |
PAK6,CDC42EP4,CDC42SE1,CDC42EP2,CDC42EP3,PAK5,CDC42SE2,WASL,PAK2 |
| 3.771e-02 | -3.28 | CRIB domain | gene3d domains | 3.90.810.10 | 10 | 6 | 14470 | 4137 |
CDC42SE1,CDC42SE2,PAK6,WASL,PAK5,PAK2 |
| 3.773e-02 | -3.28 | PINT | smart domains | SM00088 | 16 | 8 | 9717 | 2575 |
COPS7A,EIF3E,PSMD12,COPS2,PSMD3,PSMD6,COPS4,COPS7B |
| 3.778e-02 | -3.28 | negative regulation of immune response | biological process | GO:0050777 | 197 | 70 | 18204 | 5365 |
CD80,YTHDF2,ARG2,NPY5R,OAS1,SAMHD1,NLRP6,IFNB1,LYAR,LGALS3,TNFRSF14,FURIN,NMI,RC3H2,CNOT7,NR1H2,SERPINB9,MAVS,MIR105-1,PPARG,SFN,CCR2,IL2,CD46,IFI16,LILRB4,BANF1,KLRD1,IFNA2,MIR21,CLEC12B,SOCS5,IL20RB,CD59,STAT2,YWHAZ,NDFIP1,FAM3A,EIF4E2,PDCD1,USP38,TNFAIP3,YES1,GPX1,GPR17,IL10,DUSP22,IL12B,MUL1,XCL1,FGR,FCGR2B,STAT6,FGL2,USP15,ISG15,SELENOS,DUSP10,TRIM27,PSMA1,TRIM21,COL3A1,SYK,PSMB4,LILRB1,BCL6,TRAFD1,SRC,FOXP3,HFE |
| 3.780e-02 | -3.28 | acinic_cell_carcinoma | COSMIC cancer mutations | acinic_cell_carcinoma | 31 | 14 | 16828 | 4835 |
STK11,SMAD4,KRAS,HRAS,ARHGAP5,EP300,PIK3CA,PTEN,CTNNB1,MET,LRRC1,TP53,ETV6,FBXW7 |
| 3.780e-02 | -3.28 | G-protein beta/gamma-subunit complex binding | molecular function | GO:0031683 | 22 | 11 | 18094 | 5411 |
ADORA1,CETN3,GNAI3,PLCB2,GNAO1,GNA11,GNA14,CETN2,GNAQ,GNAZ,GNAI2 |
| 3.780e-02 | -3.28 | phosphotransferase activity, for other substituted phosphate groups | molecular function | GO:0016780 | 22 | 11 | 18094 | 5411 |
GNPTG,FKRP,DPAGT1,AASDHPPT,SELENOI,FKTN,PTDSS1,CDIPT,SGMS1,PGS1,SGMS2 |
| 3.780e-02 | -3.28 | insulin receptor binding | molecular function | GO:0005158 | 22 | 11 | 18094 | 5411 |
PTPN11,SHC1,SNX2,SRC,IGF1,GRB10,LMBRD1,IGF1R,SNX1,PIK3R1,PTPN1 |
| 3.782e-02 | -3.27 | asymmetric synapse | cellular component | GO:0032279 | 333 | 112 | 19108 | 5553 |
NETO1,RPS3,TIAM1,PKP4,CDK5R1,ADD1,SYNDIG1,CPEB1,HOMER3,GNG3,RPS13,LIN7C,TMEM108,RPLP0,SEMA4C,HNRNPD,EPS8,RGS7BP,PRNP,RPL10A,INSYN2A,RPS14,NETO2,INSYN1,C1QL2,ABHD17A,SIPA1L1,RNF10,PTEN,PDE4B,LRRTM2,RTN4,DLG3,GRIA1,SLC4A8,CACNG3,INPP4A,PAK2,GRID1,FAM81A,PAK6,MTMR2,GRIA2,SLC8A1,CLSTN3,NLGN1,BMPR2,RHEB,PICK1,CAMK2N1,HOMER1,SH2D5,CHMP2B,SPTBN1,GPHN,DGCR8,SLC1A1,IGSF11,TNIK,DISC1,CDK5,RPL7,DRP2,PRRT1,LRFN3,INSYN2B,MAP1B,ATP1A1,PHB2,RPL8,KCNH1,YWHAH,RPL6,DNM2,C1QL1,P2RY1,FABP5,LRRTM3,CTNND1,RPL12,SLITRK1,LRRC4B,HNRNPH2,DAPK1,NPTN,DLG1,NTRK2,GRIK1,EPHA4,IQSEC1,GRM1,CAP2,DROSHA,BAALC,ZDHHC15,SYN3,PLXNC1,LIN7B,CTNNB1,DLG4,SPOCK1,ARF1,CHRM1,LRRC4,KPNA1,USP8,FLRT3,ADORA1,SIGMAR1,HSPA8,EIF3E,ADD2 |
| 3.784e-02 | -3.27 | TXLNA (taxilin alpha) | protein interactions | 200081 | 226 | 76 | 19454 | 5460 |
YWHAZ,CYP1A1,BRCA1,CCHCR1,HSP90AA1,PSMA4,CUL3,TTC33,GORASP2,TBC1D1,UFD1,SMARCE1,BTF3,TXNDC12,DYRK1A,NMI,NFKBIB,TRIM44,CCNF,TRAF7,RPA2,PIH1D1,FAM81A,CDR2,TFIP11,TANK,ATG16L1,NUP62,H1-5,SNRNP27,KRT222,STAU1,MARS1,XRCC5,NKAPD1,LCA5,GRAMD2B,EP300,PPM1B,RASSF8,MED4,STX1A,NDC80,HENMT1,PDIA3,HMGA1,KARS1,MOV10,BTF3L4,GAS8,BRMS1L,CGAS,PRNP,HYPK,FZR1,CDC5L,WIF1,DHX15,HSP90AB1,EGLN3,CEP57L1,SDHB,PSME2,DNAJC2,STMN2,DMAP1,STX12,GFOD2,RAF1,TBK1,AZI2,CCAR1,RINT1,SIKE1,CPNE2,RUVBL2 |
| 3.788e-02 | -3.27 | Golgi cisterna | cellular component | GO:0031985 | 116 | 43 | 19108 | 5553 |
INPP5E,CHPF2,ZDHHC14,STX16,B4GALT1,CSGALNACT2,NSG1,TMEM115,SCFD1,PSENEN,CSGALNACT1,B4GALT6,TMEM59,ST3GAL2,B4GALT3,FUT1,GOLGA5,ATP2C1,GAL3ST4,APH1A,MOB4,SLC30A5,GGTA1,ST6GAL1,TMED3,SLC30A7,SAR1B,ATL1,B4GALT7,GPR89A,TMEM87A,FUT8,GOLPH3L,GOSR1,GALNT1,SGMS1,GCC1,LYSET,CHPF,GALNT2,RAB30,ST3GAL1,ST3GAL4 |
| 3.791e-02 | -3.27 | siRNA binding | molecular function | GO:0035197 | 12 | 7 | 18094 | 5411 |
TLR7,DICER1,MECP2,DHX9,TLR9,ARB2A,PRKRA |
| 3.791e-02 | -3.27 | phosphatidylinositol-4,5-bisphosphate phosphatase activity | molecular function | GO:0106019 | 12 | 7 | 18094 | 5411 |
PTPMT1,PIP4P2,PIP4P1,OCRL,INPP5K,FIG4,INPP5E |
| 3.791e-02 | -3.27 | cytidine deaminase activity | molecular function | GO:0004126 | 12 | 7 | 18094 | 5411 |
APOBEC3C,APOBEC3B,APOBEC3G,APOBEC3F,APOBEC3H,APOBEC3A,APOBEC3D |
| 3.796e-02 | -3.27 | Fentanyl Action Pathway | SMPDB pathways | SMP0000415 | 26 | 15 | 1369 | 531 |
SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2,OPRM1,ATP1B3,ATP1B1,ATP1A3,ADRA1A,HTR1A,DRD1,SCN1B |
| 3.796e-02 | -3.27 | Oxymorphone Action Pathway | SMPDB pathways | SMP0000412 | 26 | 15 | 1369 | 531 |
KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3,HTR1A,DRD1,ADRA1A,SCN1B,ATP1B3,ATP1A3,ATP1B1,OPRM1 |
| 3.796e-02 | -3.27 | Propoxyphene Action Pathway | SMPDB pathways | SMP0000672 | 26 | 15 | 1369 | 531 |
KCND2,ATP1A1,SLC6A3,KCNIP2,SLC6A2,SLC6A4,ATP1A2,ATP1A3,ATP1B3,ATP1B1,OPRM1,SCN1B,HTR1A,DRD1,ADRA1A |
| 3.796e-02 | -3.27 | Diphenoxylate Action Pathway | SMPDB pathways | SMP0000675 | 26 | 15 | 1369 | 531 |
ATP1A1,SLC6A3,KCND2,SLC6A4,ATP1A2,KCNIP2,SLC6A2,OPRM1,ATP1A3,ATP1B1,ATP1B3,ADRA1A,DRD1,HTR1A,SCN1B |
| 3.796e-02 | -3.27 | Bupivacaine Action Pathway | SMPDB pathways | SMP0000393 | 26 | 15 | 1369 | 531 |
OPRM1,ATP1A3,ATP1B1,ATP1B3,SCN1B,ADRA1A,DRD1,HTR1A,SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2 |
| 3.796e-02 | -3.27 | Dibucaine Action Pathway | SMPDB pathways | SMP0000396 | 26 | 15 | 1369 | 531 |
KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3,SCN1B,HTR1A,DRD1,ADRA1A,ATP1A3,ATP1B1,ATP1B3,OPRM1 |
| 3.796e-02 | -3.27 | The Oncogenic Action of 2-Hydroxyglutarate | SMPDB pathways | SMP0002291 | 26 | 15 | 1369 | 531 |
IDH2,SUCLG2,ACO1,SDHC,PDHB,DLST,IDH3B,IDH1,SDHB,IDH3A,KDM2A,ACO2,DLAT,MPC1,PC |
| 3.796e-02 | -3.27 | Naltrexone Action Pathway | SMPDB pathways | SMP0000687 | 26 | 15 | 1369 | 531 |
OPRM1,ATP1B3,ATP1A3,ATP1B1,ADRA1A,DRD1,HTR1A,SCN1B,SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2 |
| 3.796e-02 | -3.27 | 3-Methylthiofentanyl Action Pathway | SMPDB pathways | SMP0000679 | 26 | 15 | 1369 | 531 |
OPRM1,ATP1A3,ATP1B1,ATP1B3,ADRA1A,HTR1A,DRD1,SCN1B,SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2 |
| 3.796e-02 | -3.27 | Oxycodone Action Pathway | SMPDB pathways | SMP0000409 | 26 | 15 | 1369 | 531 |
SLC6A4,ATP1A2,KCNIP2,SLC6A2,ATP1A1,SLC6A3,KCND2,ADRA1A,HTR1A,DRD1,SCN1B,OPRM1,ATP1B3,ATP1B1,ATP1A3 |
| 3.796e-02 | -3.27 | Alvimopan Action Pathway | SMPDB pathways | SMP0000685 | 26 | 15 | 1369 | 531 |
ATP1A3,ATP1B3,ATP1B1,OPRM1,DRD1,HTR1A,ADRA1A,SCN1B,KCND2,ATP1A1,SLC6A3,KCNIP2,SLC6A2,SLC6A4,ATP1A2 |
| 3.796e-02 | -3.27 | Dihydromorphine Action Pathway | SMPDB pathways | SMP0000689 | 26 | 15 | 1369 | 531 |
OPRM1,ATP1B3,ATP1A3,ATP1B1,ADRA1A,HTR1A,DRD1,SCN1B,SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2 |
| 3.796e-02 | -3.27 | Sufentanil Action Pathway | SMPDB pathways | SMP0000417 | 26 | 15 | 1369 | 531 |
DRD1,HTR1A,ADRA1A,SCN1B,ATP1A3,ATP1B1,ATP1B3,OPRM1,SLC6A2,KCNIP2,ATP1A2,SLC6A4,KCND2,SLC6A3,ATP1A1 |
| 3.796e-02 | -3.27 | Levomethadyl Acetate Action Action Pathway | SMPDB pathways | SMP0000677 | 26 | 15 | 1369 | 531 |
KCND2,SLC6A3,ATP1A1,SLC6A2,KCNIP2,ATP1A2,SLC6A4,ATP1A3,ATP1B1,ATP1B3,OPRM1,SCN1B,HTR1A,DRD1,ADRA1A |
| 3.796e-02 | -3.27 | Procaine Action Pathway | SMPDB pathways | SMP0000402 | 26 | 15 | 1369 | 531 |
SCN1B,DRD1,HTR1A,ADRA1A,ATP1A3,ATP1B1,ATP1B3,OPRM1,KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3 |
| 3.796e-02 | -3.27 | Chloroprocaine Action Pathway | SMPDB pathways | SMP0000394 | 26 | 15 | 1369 | 531 |
SLC6A2,KCNIP2,ATP1A2,SLC6A4,KCND2,SLC6A3,ATP1A1,SCN1B,DRD1,HTR1A,ADRA1A,ATP1B1,ATP1B3,ATP1A3,OPRM1 |
| 3.796e-02 | -3.27 | Oxybuprocaine Action Pathway | SMPDB pathways | SMP0000400 | 26 | 15 | 1369 | 531 |
OPRM1,ATP1B1,ATP1A3,ATP1B3,SCN1B,ADRA1A,DRD1,HTR1A,ATP1A1,SLC6A3,KCND2,SLC6A4,ATP1A2,KCNIP2,SLC6A2 |
| 3.796e-02 | -3.27 | Proparacaine Action Pathway | SMPDB pathways | SMP0000403 | 26 | 15 | 1369 | 531 |
DRD1,HTR1A,ADRA1A,SCN1B,ATP1B1,ATP1A3,ATP1B3,OPRM1,KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3 |
| 3.796e-02 | -3.27 | Hydrocodone Action Pathway | SMPDB pathways | SMP0000411 | 26 | 15 | 1369 | 531 |
HTR1A,DRD1,ADRA1A,SCN1B,ATP1B1,ATP1A3,ATP1B3,OPRM1,KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3 |
| 3.796e-02 | -3.27 | Tramadol Action Action Pathway | SMPDB pathways | SMP0000671 | 26 | 15 | 1369 | 531 |
OPRM1,ATP1B3,ATP1B1,ATP1A3,ADRA1A,HTR1A,DRD1,SCN1B,ATP1A1,SLC6A3,KCND2,SLC6A4,ATP1A2,KCNIP2,SLC6A2 |
| 3.796e-02 | -3.27 | Dimethylthiambutene Action Pathway | SMPDB pathways | SMP0000680 | 26 | 15 | 1369 | 531 |
KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3,SCN1B,HTR1A,DRD1,ADRA1A,ATP1A3,ATP1B1,ATP1B3,OPRM1 |
| 3.796e-02 | -3.27 | Levobupivacaine Action Pathway | SMPDB pathways | SMP0000397 | 26 | 15 | 1369 | 531 |
SCN1B,HTR1A,DRD1,ADRA1A,ATP1A3,ATP1B3,ATP1B1,OPRM1,SLC6A2,KCNIP2,ATP1A2,SLC6A4,KCND2,SLC6A3,ATP1A1 |
| 3.796e-02 | -3.27 | Anileridine Action Pathway | SMPDB pathways | SMP0000674 | 26 | 15 | 1369 | 531 |
ATP1A1,SLC6A3,KCND2,SLC6A4,ATP1A2,KCNIP2,SLC6A2,OPRM1,ATP1B3,ATP1A3,ATP1B1,SCN1B,ADRA1A,DRD1,HTR1A |
| 3.796e-02 | -3.27 | Pentazocine Action Pathway | SMPDB pathways | SMP0000686 | 26 | 15 | 1369 | 531 |
ATP1B3,ATP1A3,ATP1B1,OPRM1,HTR1A,DRD1,ADRA1A,SCN1B,KCND2,SLC6A3,ATP1A1,SLC6A2,KCNIP2,ATP1A2,SLC6A4 |
| 3.796e-02 | -3.27 | Levallorphan Action Pathway | SMPDB pathways | SMP0000683 | 26 | 15 | 1369 | 531 |
KCND2,ATP1A1,SLC6A3,KCNIP2,SLC6A2,SLC6A4,ATP1A2,ATP1A3,ATP1B1,ATP1B3,OPRM1,HTR1A,DRD1,ADRA1A,SCN1B |
| 3.796e-02 | -3.27 | Ketobemidone Action Pathway | SMPDB pathways | SMP0000690 | 26 | 15 | 1369 | 531 |
ATP1A3,ATP1B1,ATP1B3,OPRM1,DRD1,HTR1A,ADRA1A,SCN1B,KCND2,ATP1A1,SLC6A3,KCNIP2,SLC6A2,SLC6A4,ATP1A2 |
| 3.796e-02 | -3.27 | Methadyl Acetate Action Pathway | SMPDB pathways | SMP0000678 | 26 | 15 | 1369 | 531 |
SCN1B,ADRA1A,DRD1,HTR1A,OPRM1,ATP1B1,ATP1B3,ATP1A3,SLC6A4,ATP1A2,KCNIP2,SLC6A2,ATP1A1,SLC6A3,KCND2 |
| 3.796e-02 | -3.27 | Carfentanil Action Pathway | SMPDB pathways | SMP0000414 | 26 | 15 | 1369 | 531 |
ATP1B1,ATP1A3,ATP1B3,OPRM1,SCN1B,HTR1A,DRD1,ADRA1A,KCND2,SLC6A3,ATP1A1,SLC6A2,KCNIP2,ATP1A2,SLC6A4 |
| 3.796e-02 | -3.27 | Ethylmorphine Action Pathway | SMPDB pathways | SMP0000681 | 26 | 15 | 1369 | 531 |
HTR1A,DRD1,ADRA1A,SCN1B,ATP1A3,ATP1B1,ATP1B3,OPRM1,SLC6A2,KCNIP2,ATP1A2,SLC6A4,KCND2,SLC6A3,ATP1A1 |
| 3.796e-02 | -3.27 | Ropivacaine Action Pathway | SMPDB pathways | SMP0000404 | 26 | 15 | 1369 | 531 |
SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2,OPRM1,ATP1A3,ATP1B3,ATP1B1,SCN1B,ADRA1A,HTR1A,DRD1 |
| 3.796e-02 | -3.27 | Cocaine Action Pathway | SMPDB pathways | SMP0000395 | 26 | 15 | 1369 | 531 |
KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3,SCN1B,DRD1,HTR1A,ADRA1A,ATP1A3,ATP1B3,ATP1B1,OPRM1 |
| 3.796e-02 | -3.27 | Benzocaine Action Pathway | SMPDB pathways | SMP0000392 | 26 | 15 | 1369 | 531 |
SCN1B,ADRA1A,HTR1A,DRD1,OPRM1,ATP1B3,ATP1B1,ATP1A3,SLC6A4,ATP1A2,KCNIP2,SLC6A2,ATP1A1,SLC6A3,KCND2 |
| 3.796e-02 | -3.27 | Alfentanil Action Pathway | SMPDB pathways | SMP0000413 | 26 | 15 | 1369 | 531 |
KCND2,SLC6A3,ATP1A1,SLC6A2,KCNIP2,ATP1A2,SLC6A4,ATP1A3,ATP1B1,ATP1B3,OPRM1,SCN1B,HTR1A,DRD1,ADRA1A |
| 3.796e-02 | -3.27 | Prilocaine Action Pathway | SMPDB pathways | SMP0000401 | 26 | 15 | 1369 | 531 |
ATP1A1,SLC6A3,KCND2,SLC6A4,ATP1A2,KCNIP2,SLC6A2,OPRM1,ATP1B3,ATP1B1,ATP1A3,ADRA1A,DRD1,HTR1A,SCN1B |
| 3.796e-02 | -3.27 | Remifentanil Action Pathway | SMPDB pathways | SMP0000416 | 26 | 15 | 1369 | 531 |
KCND2,ATP1A1,SLC6A3,KCNIP2,SLC6A2,SLC6A4,ATP1A2,ATP1B3,ATP1A3,ATP1B1,OPRM1,SCN1B,DRD1,HTR1A,ADRA1A |
| 3.796e-02 | -3.27 | Naloxone Action Pathway | SMPDB pathways | SMP0000688 | 26 | 15 | 1369 | 531 |
SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2,OPRM1,ATP1A3,ATP1B3,ATP1B1,ADRA1A,DRD1,HTR1A,SCN1B |
| 3.796e-02 | -3.27 | Dezocine Action Pathway | SMPDB pathways | SMP0000676 | 26 | 15 | 1369 | 531 |
HTR1A,DRD1,ADRA1A,SCN1B,ATP1B1,ATP1B3,ATP1A3,OPRM1,KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3 |
| 3.796e-02 | -3.27 | Buprenorphine Action Pathway | SMPDB pathways | SMP0000684 | 26 | 15 | 1369 | 531 |
HTR1A,DRD1,ADRA1A,SCN1B,ATP1B1,ATP1A3,ATP1B3,OPRM1,KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3 |
| 3.796e-02 | -3.27 | Levorphanol Action Pathway | SMPDB pathways | SMP0000673 | 26 | 15 | 1369 | 531 |
DRD1,HTR1A,ADRA1A,SCN1B,ATP1B1,ATP1A3,ATP1B3,OPRM1,KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3 |
| 3.796e-02 | -3.27 | Escitalopram Action Pathway | SMPDB pathways | SMP0000425 | 26 | 15 | 1369 | 531 |
KCNIP2,SLC6A2,SLC6A4,ATP1A2,KCND2,ATP1A1,SLC6A3,DRD1,HTR1A,ADRA1A,SCN1B,ATP1A3,ATP1B3,ATP1B1,OPRM1 |
| 3.796e-02 | -3.27 | Hydromorphone Action Pathway | SMPDB pathways | SMP0000410 | 26 | 15 | 1369 | 531 |
ATP1A1,SLC6A3,KCND2,SLC6A4,ATP1A2,KCNIP2,SLC6A2,OPRM1,ATP1A3,ATP1B1,ATP1B3,ADRA1A,HTR1A,DRD1,SCN1B |
| 3.796e-02 | -3.27 | Mepivacaine Action Pathway | SMPDB pathways | SMP0000399 | 26 | 15 | 1369 | 531 |
SLC6A3,ATP1A1,KCND2,ATP1A2,SLC6A4,SLC6A2,KCNIP2,OPRM1,ATP1B3,ATP1A3,ATP1B1,ADRA1A,DRD1,HTR1A,SCN1B |
| 3.802e-02 | -3.27 | IL27-mediated signaling events | Pathway Interaction DB | il27pathway | 26 | 14 | 2226 | 782 |
IL2,IL12A,IFNG,IL1B,IL12B,IL6ST,STAT1,JAK2,STAT2,JAK1,TNF,STAT5A,IL18,IL6 |
| 3.803e-02 | -3.27 | steroid binding | molecular function | GO:0005496 | 107 | 41 | 18094 | 5411 |
PAQR8,MINAR2,SYP,PMP2,PDIA2,VDAC1,UGT1A1,AR,NPC2,PROM1,TMEM97,CYP21A2,ATP1A1,EPHX1,PGRMC1,ATP1A3,ATP1A2,HSD17B1,INSIG2,ERLIN2,CYP2R1,TSPO2,CD81,STARD5,VDR,STAR,STARD3NL,OSBP,PGR,VDAC2,NPC1L1,TSPO,ERLIN1,TMEM199,PAQR9,ESR2,STARD4,CAV1,HSD11B1,SLC38A9,OSBPL8 |
| 3.807e-02 | -3.27 | regulation of neuron projection development | biological process | GO:0010975 | 443 | 148 | 18204 | 5365 |
SHOC2,TNIK,AP2A1,PTN,PAQR3,CAMK1,PSEN1,STMN2,NTRK3,ANAPC2,FZD4,NTRK2,SNX3,GPRASP3,PQBP1,AMIGO1,NPTN,NR2E1,RAP2A,GFI1,STK24,SMURF1,RTN4,EZH2,CHRNB2,EFNA5,FKBP1B,BMPR2,SNAPIN,MIR210,B2M,VEGFA,SEMA7A,SIPA1L1,SLITRK1,FBXO7,NFE2L2,EPO,PAX6,THY1,CDK5R1,PMP22,CFL1,SNAP25,ENC1,KLF4,UST,MGARP,YWHAH,SERPINI1,NEGR1,FGFR1,NCKIPSD,PLXNC1,CRABP2,CRMP1,EHD1,ITGA6,SCN1B,SDC2,IGF1R,SFRP1,NEO1,EPHA4,THOC2,TMEM30A,NLGN1,UBE3A,CAMSAP2,MIR133B,PAFAH1B1,ZDHHC15,MDM2,TIAM1,LPAR1,RND2,IFRD1,CNR1,TENM3,CRKL,FEZ1,ARF6,MIR221,PAK2,MYLIP,TNR,FKBP4,CNTN1,MIR222,CTNNA2,CD38,NEFL,DDR1,P3H1,ZNF365,RGMA,ATF1,ADNP,FGF13,L1CAM,FUT9,IL15RA,GSK3A,MAP2K1,RETREG3,VLDLR,RIT2,KDM1A,NRP1,MIR200C,DISC1,PTEN,STK11,SEMA5A,TBC1D24,TRIM46,HECW1,HDAC6,DKK1,KLK6,SPOCK1,CXCL12,AKT1,NTNG2,SPP1,MINAR1,RGS2,CDK5,PTK7,NDNF,ELAVL4,YTHDF1,WNT7A,PPP3CA,MT3,NCK1,TMEM106B,TOX,RAB29,RAP1A,MAP1B,CERS2,CX3CL1,CAMK2G,PPFIA2,ALKAL1,EP300,SARM1 |
| 3.818e-02 | -3.27 | SHANK3 (SH3 and multiple ankyrin repeat domains 3) | protein interactions | 85358 | 171 | 59 | 19454 | 5460 |
NRBF2,ABCC2,CLU,PDHB,USP8,ARPC2,NGRN,TFIP11,FRS3,WWP1,VPS18,PRMT2,SLC48A1,NOTCH2,SNRPN,CHCHD3,VIRMA,PSMD4,HECW1,CSNK2B,TRIM27,PHF12,CTTN,NCKIPSD,ICA1,BTF3,FBXO7,PPP1CC,LRRC73,HNRNPC,PAX6,CA10,FKBP8,THRAP3,HNRNPK,PICK1,RPL3,CRELD1,CIBAR1,CRKL,HGS,NEFL,ARHGAP12,GPR162,TP53,KIAA0232,SPTAN1,PRNP,NELL2,TSG101,DLGAP4,DNM2,HOMER3,RBM5,EID1,TDRD7,NCK1,COPS5,GAPDH |
| 3.820e-02 | -3.26 | negative regulation of TOR signaling | biological process | GO:0032007 | 70 | 28 | 18204 | 5365 |
UBE2W,YWHAG,UBE3A,MAPKAPK5,SAR1B,CRYBA1,GSK3A,FLCN,SEC13,SESN3,RNF152,KICS2,TMEM127,PRKACB,MINAR1,YWHAZ,SESN2,MIOS,SH3BP4,CASTOR2,DDIT4,MTM1,TNFAIP8L1,UBE2N,TBK1,RNF167,STK11,UBE2D1 |
| 3.820e-02 | -3.26 | positive regulation of reactive oxygen species metabolic process | biological process | GO:2000379 | 70 | 28 | 18204 | 5365 |
CD36,CLEC7A,GSTP1,RAB27A,SOD2,AKR1C1,NFE2L2,TYROBP,ROMO1,TP53,CDKN1A,MIR675,MIR24-1,DUOXA2,TGFBR2,TLR6,F2,DHRS4,LEP,RNF41,TLR4,SOD1,TSPO,SYK,PID1,CYP1B1,GNAI2,GADD45A |
| 3.820e-02 | -3.26 | positive regulation of T cell mediated immunity | biological process | GO:0002711 | 70 | 28 | 18204 | 5365 |
STX7,CD1E,IL12B,XCL1,IL23A,B2M,TRAF2,RSAD2,IL6,SASH3,CD1D,IL18,TRAF6,HFE,FOXP3,IL12A,NLRP3,HSPD1,CD1B,IL1B,HSPA8,CD1C,IL4,MICB,NECTIN2,CYRIB,CD1A,CD81 |
| 3.826e-02 | -3.26 | TMEM51 (transmembrane protein 51) | protein interactions | 55092 | 98 | 36 | 19454 | 5460 |
RHOJ,REEP4,ARF6,VTI1B,CAV1,STX6,DIRAS3,TMEM14A,CYB5R3,HRAS,RAB35,GJA1,LAMTOR1,PDCD4,RAB11A,PTPN5,WWP2,EPS8,DPP4,CREB3,LAMP3,TMEM107,KRAS,SFT2D2,STX7,TMX2,GALC,TMEM254,SEC61G,WWP1,LMNA,TMEM14B,MRPL12,METTL15,CCDC167,PLP2 |
| 3.826e-02 | -3.26 | GCC1 (GRIP and coiled-coil domain containing 1) | protein interactions | 79571 | 98 | 36 | 19454 | 5460 |
COIL,OIP5,PPP1R27,GTF2I,KDM1A,BIRC2,KATNAL1,LCA5,TFIP11,DISC1,ZC4H2,PAK5,BET1,JPH4,TMEM170A,VIRMA,CAV1,STX6,PRPF18,TRIM29,PPP1R18,GJA1,HRAS,NAB2,MED4,BRCA1,SPOP,GCC1,FAM83A,GAS8,CCDC85B,CEP70,RUNX1,ATF4,ATG9A,PRPF19 |
| 3.827e-02 | -3.26 | negative regulation of organelle assembly | biological process | GO:1902116 | 47 | 20 | 18204 | 5365 |
TRIM37,PHF23,LPAR1,AKT1,TMEM39A,BRCA1,TESK1,CEP97,BECN1,TRIM32,SEC22B,SCFD1,GDI2,CAV3,SMAD4,WDR44,FEZ1,MAP4,MTM1,NUPR1 |
| 3.827e-02 | -3.26 | negative regulation of MAP kinase activity | biological process | GO:0043407 | 47 | 20 | 18204 | 5365 |
ADIPOQ,PTPN22,IL1B,RGS2,PTPN1,INPP5K,PPARG,GSTP1,HYAL2,MIR218-1,CDK5RAP3,SPRY1,PDCD4,PAQR3,DUSP1,CAV3,DUSP10,STK38,DUSP19,DEFB114 |
| 3.827e-02 | -3.26 | negative regulation of peptide secretion | biological process | GO:0002792 | 47 | 20 | 18204 | 5365 |
CARTPT,HADH,LEP,GNAO1,JAGN1,FKBP1B,CRHBP,CCN3,PTPN11,CHGA,SFRP1,NDUFAF2,KCNJ11,UCP2,PPP3CA,ACVR1C,GNAZ,ENY2,GHRL,KCNB1 |
| 3.839e-02 | -3.26 | secretion | biological process | GO:0046903 | 536 | 177 | 18204 | 5365 |
LIN7C,STX17,FZD4,NIBAN2,NTRK2,CPLX1,DNAJC5,TPD52,SNCG,CDO1,VEGFA,RAB3C,MECP2,SLC51A,PTGDS,PIK3CG,RAB40AL,LEP,CCL8,ADORA1,SCAMP5,OLFM2,COMT,NME1,TMEM38B,SYT2,RAB8B,NEO1,SVBP,SNX10,NLGN1,PPFIA3,PAFAH1B1,ARFGAP3,UMPS,STAT5A,VIP,EXOC5,GRM2,SLC29A1,EXOC8,VAMP3,EXOC3,USE1,SNAP23,GJA1,CFTR,CD2AP,CKLF,DDR1,RAB31,KCNJ8,CACNB4,SLC16A10,CHRM3,EXOC2,CBLN4,VAMP2,NHERF1,PRSS12,SYNGR3,STX11,SELENOT,TMEM167B,LIN7B,S100A8,RAB11B,ARL4D,ARFGEF1,CDK5,STX1A,FGF7,SYK,VAMP7,CLTRN,YKT6,RAB11A,LACRT,CRHBP,HRH3,ASIC1,RAP1A,MRGPRX2,RAF1,PPT1,PSEN1,SYT4,CCDC186,SMAD2,EXOC1,SLC38A3,ILDR1,VTI1B,LGI3,SYN3,VPS18,FKBP1B,BLOC1S3,SLC32A1,SNAPIN,PNPLA8,RAB1A,FURIN,CAV1,TSPAN18,UPRT,SNAP25,MIA2,CHRM5,CSF2,SNAP29,SCG2,CA2,CPLX3,APLN,PRL,CCL3,HNF1B,SOCS2,GNAO1,TRAF3IP2,ERP29,CREB1,IL6,RIMS3,ACVR1C,CCL5,KCNB1,CARTPT,RAB13,RAB3A,LAT2,CCND1,CBLN1,NAPA,PLA2G12A,CBL,KIT,CYB5R4,CPE,GHRL,COPS5,SLC4A8,RAP1B,CRHR1,RAB27A,SYNGR1,FOSL2,CHGA,PRKCE,CPLX2,CCR1,PLA2G5,HPS6,CHRM1,TSG101,STXBP1,PPY,TVP23B,DRD3,AGR2,VAMP8,SELENOM,WNT7A,RAB3B,RALA,FBLN5,OXTR,JAGN1,RAB3D,FGF10,VDR,SYNGR2,HRH2,CAMK2G,SLC6A3,RIMS4 |
| 3.839e-02 | -3.26 | TXNDC9 (thioredoxin domain containing 9) | protein interactions | 10190 | 120 | 43 | 19454 | 5460 |
TUBB4B,KBTBD4,CCT5,ACTR1A,TUBA1A,EXOSC8,UBR7,HUWE1,RASL10B,PICK1,TUBG1,MED4,ZCCHC10,B9D1,SPPL3,TCP1,EGLN3,CCDC172,CCT7,COX14,FEZ1,ARL4D,SAMM50,LSM2,UBE2M,MRPL12,PTN,FBXW4,ARFIP1,CCT2,DCAF4,TRIM23,MYC,KLHDC8A,MED22,PRDX2,TUBB,DUSP10,PNMA1,SCNM1,TUBA1B,TRIM27,ZNF655 |
| 3.839e-02 | -3.26 | NPRL2 (NPR2 like, GATOR1 complex subunit) | protein interactions | 10641 | 120 | 43 | 19454 | 5460 |
FEM1B,CTNNB1,MOV10,VCPIP1,SMG8,NAB2,CBL,EED,MIOS,RAB1B,MTCH2,B3GNT2,SESN2,TRAPPC13,IGF1R,SLC39A7,RUVBL2,RAB1A,GTF3C3,KRAS,RRAGB,ARL5B,CFL1,FBXO7,RSPH1,HSP90AA1,CHRAC1,B4GALT1,STUB1,ARF1,APEX1,MATR3,CDKN1A,RRAGA,ANXA7,UBE2M,CTBP1,KICS2,EP300,APPBP2,HSPA8,ZBTB5,YTHDF1 |
| 3.839e-02 | -3.26 | ACSL4 (acyl-CoA synthetase long chain family member 4) | protein interactions | 2182 | 120 | 43 | 19454 | 5460 |
RPA2,SH3GLB1,TOR1AIP2,TP53,RAF1,CFTR,CDC42,CNPY3,TGFBR2,SLC15A1,KRAS,TNFSF8,SLC31A1,NDUFA4,PML,RPA3,MME,AKAP1,RAB5A,NUBP2,HSPA8,RHOB,BRCA1,SLC2A1,NRP1,HNRNPD,NTRK3,FOXA3,EDEM1,TNFAIP3,MYC,LCN6,HDAC6,H2BC9,OPRL1,SH3BGRL,PHB1,HRAS,COQ8A,BRINP2,SLC1A1,HSD11B1,PTPMT1 |
| 3.843e-02 | -3.26 | main axon | cellular component | GO:0044304 | 68 | 27 | 19108 | 5553 |
ADORA1,SLC1A2,TRIM46,KCNJ11,SCN1B,MAP1B,TNFRSF1B,DLG4,SPOCK1,KCNA2,DAG1,UCN,LGI3,GABBR1,CNTNAP1,HAPLN2,THY1,KCNAB1,CNTN2,CD40,DLG1,CRHBP,TIAM1,C9orf72,LGI1,SPTBN1,KCNC1 |
| 3.851e-02 | -3.26 | human chr2q35 | chromosome location | human chr2q35 | 95 | 29 | 26134 | 5823 |
ZFAND2B,CRYBA2,CYP27A1,ATG9A,MIR375,GMPPA,MREG,CHPF,RPL37A,TMBIM1,BCS1L,CTDSP1,RETREG2,INHA,XRCC5,TMEM198,ARPC2,CNPPD1,GPBAR1,MIR26B,DES,CXCR1,AAMP,DNAJB2,MIR153-1,MARCHF4,NHEJ1,CATIP,STK16 |
| 3.860e-02 | -3.25 | RPGRIP1L (RPGRIP1 like) | protein interactions | 23322 | 184 | 63 | 19454 | 5460 |
NOC4L,TRIM37,CAPZA1,ABCF1,PPP1R12A,ACADSB,CAPZA2,PNMA2,TFRC,VPS33A,EZH2,TP53,IPO8,HSDL2,RAF1,ERLIN2,KIF2A,ERLIN1,DBT,ILVBL,NDUFB4,WDCP,KRT8,TYMS,PSMD7,SSX2IP,SPATS2L,NDC80,ABRACL,INSYN1,YWHAH,SRSF2,KDM1A,FTL,TRIM52,DVL2,LCA5,TMEM256,KCTD12,HECTD1,ATG16L1,WDR83,HACD2,RAB6A,CD2AP,IDH3B,SIPA1L1,GKAP1,DYNLL1,RPP25L,CTSB,GPX1,SEC63,CEP97,CCSER2,TRIM27,RMDN3,GANAB,MOB4,CHTOP,CEP85,PPP1CC,RACGAP1 |
| 3.861e-02 | -3.25 | upper_aerodigestive_tract-mouth-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-basal_cell_carcinoma | 10 | 6 | 16828 | 4835 |
TERT,TP53,HRAS,CTNNB1,KRAS,SUFU |
| 3.861e-02 | -3.25 | frontoparietal | COSMIC cancer mutations | frontoparietal | 10 | 6 | 16828 | 4835 |
TP53,CTNNB1,IDH2,SMARCB1,CDKN2C,IDH1 |
| 3.861e-02 | -3.25 | skin-shoulder-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-shoulder-carcinoma-basal_cell_carcinoma | 10 | 6 | 16828 | 4835 |
SUFU,TERT,TP53,HRAS,KRAS,CTNNB1 |
| 3.861e-02 | -3.25 | clear_cell | COSMIC cancer mutations | clear_cell | 10 | 6 | 16828 | 4835 |
IDH2,IDH1,AKT1,NF2,PTEN,PIK3CA |
| 3.861e-02 | -3.25 | skin-back-malignant_melanoma-nodular | COSMIC cancer mutations | skin-back-malignant_melanoma-nodular | 10 | 6 | 16828 | 4835 |
GNAQ,KRAS,CTNNB1,GNA11,KIT,HRAS |
| 3.861e-02 | -3.25 | intradermal | COSMIC cancer mutations | intradermal | 10 | 6 | 16828 | 4835 |
HRAS,KIT,KRAS,BAP1,GNAQ,PIK3CA |
| 3.861e-02 | -3.25 | bone-rib-chondrosarcoma-peripheral | COSMIC cancer mutations | bone-rib-chondrosarcoma-peripheral | 10 | 6 | 16828 | 4835 |
MDC1,PRSS1,IDH1,CA8,TLR9,IDH2 |
| 3.861e-02 | -3.25 | pancreas-carcinoid-endocrine_tumour-gastrinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-gastrinoma | 10 | 6 | 16828 | 4835 |
HRAS,CTNNB1,KRAS,CDKN2C,SMAD4,PTEN |
| 3.861e-02 | -3.25 | clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_papillary_renal_cell_carcinoma | 10 | 6 | 16828 | 4835 |
TP53,KRAS,IDH2,IDH1,PIK3CA,PTEN |
| 3.861e-02 | -3.25 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_III | 10 | 6 | 16828 | 4835 |
TP53,KRAS,EZH2,IDH2,MSH6,IDH1 |
| 3.861e-02 | -3.25 | lung-carcinoma-blastoma | COSMIC cancer mutations | lung-carcinoma-blastoma | 10 | 6 | 16828 | 4835 |
PIK3CA,ETV6,TP53,CTNNB1,KRAS,KIT |
| 3.861e-02 | -3.25 | large_intestine-colon-carcinoid-endocrine_tumour | COSMIC cancer mutations | large_intestine-colon-carcinoid-endocrine_tumour | 10 | 6 | 16828 | 4835 |
SMAD4,AKT1,TP53,KIT,CTNNB1,KRAS |
| 3.861e-02 | -3.25 | skin-ear-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-ear-carcinoma-basal_cell_carcinoma | 10 | 6 | 16828 | 4835 |
SUFU,TERT,TP53,HRAS,CTNNB1,KRAS |
| 3.861e-02 | -3.25 | elbow | COSMIC cancer mutations | elbow | 10 | 6 | 16828 | 4835 |
GNA11,HRAS,KRAS,TERT,BAP1,GNAQ |
| 3.861e-02 | -3.25 | genital_tract-extragonadal-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-non_seminoma | 10 | 6 | 16828 | 4835 |
CBL,PTEN,TP53,KIT,KRAS,CTNNB1 |
| 3.861e-02 | -3.25 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_II | 10 | 6 | 16828 | 4835 |
HRAS,KRAS,TP53,PTEN,IDH1,IDH2 |
| 3.861e-02 | -3.25 | bone-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-chondrosarcoma-dedifferentiated | 10 | 6 | 16828 | 4835 |
TP53,IDH2,IDH1,SS18,PIK3CA,EWSR1 |
| 3.861e-02 | -3.25 | ovary-adenoma-Brenner_tumour | COSMIC cancer mutations | ovary-adenoma-Brenner_tumour | 10 | 6 | 16828 | 4835 |
PPP2R1A,KRAS,CTNNB1,BRCA1,TP53,PIK3CA |
| 3.861e-02 | -3.25 | carcinosarcoma | COSMIC cancer mutations | carcinosarcoma | 10 | 6 | 16828 | 4835 |
TP53,CTNNB1,KRAS,KIT,MET,PIK3CA |
| 3.861e-02 | -3.25 | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | 10 | 6 | 16828 | 4835 |
PTEN,PIK3CA,IDH1,IDH2,KRAS,TP53 |
| 3.867e-02 | -3.25 | Interleukin-11 Signaling Pathway | WikiPathways | WP2332 | 44 | 22 | 5310 | 1910 |
RAF1,BIRC5,SRC,JAK2,PIK3R2,HRAS,YES1,PIAS1,JAK1,BGLAP,PTPN11,ITGA2,MAP2K1,CREB1,ICAM1,AKT1,SOCS3,IL6ST,ATF1,IKBKB,STAT1,PIK3R1 |
| 3.871e-02 | -3.25 | regulation of reactive oxygen species metabolic process | biological process | GO:2000377 | 148 | 54 | 18204 | 5365 |
ARF4,PPARA,TLR4,RNF41,LEP,TLR6,HDAC6,MIR590,MPV17,VDAC1,SYK,PRDX2,RAC2,MT3,SOD2,FBLN5,BIRC2,CRYAB,TUSC2,IER3,GSTP1,CLEC7A,MIR24-1,DUOXA2,MIR675,TP53,ROMO1,TNF,SOD1,MIR21,BECN1,DHRS4,F2,TGFBR2,G6PD,GADD45A,BRCA1,CYP1B1,GNAI2,PID1,AATF,TSPO,PRCP,PARL,RAB27A,ARG2,HP,CD36,SPHK2,ACP5,CDKN1A,TYROBP,NFE2L2,AKR1C1 |
| 3.875e-02 | -3.25 | positive regulation of smooth muscle cell differentiation | biological process | GO:0051152 | 25 | 12 | 18204 | 5365 |
MIR145,MIR1-1,PIAS1,MIR34A,SOD2,MIR21,MIR424,MIR140,SMARCD3,NOTCH2,OLFM2,KIT |
| 3.875e-02 | -3.25 | regulation of protein exit from endoplasmic reticulum | biological process | GO:0070861 | 25 | 12 | 18204 | 5365 |
SVIP,EDEM1,UBE2G2,EDEM2,SAR1B,DERL2,TM9SF4,ERLEC1,CD81,UBAC2,TMEM30A,OS9 |
| 3.875e-02 | -3.25 | xenobiotic catabolic process | biological process | GO:0042178 | 25 | 12 | 18204 | 5365 |
NR1I2,CRYZ,GSTO1,GSTM2,CYP2C9,UGT1A1,CYP2D6,CYP3A5,GSTM3,GSTM4,CYP2C8,CYP1A1 |
| 3.875e-02 | -3.25 | response to increased oxygen levels | biological process | GO:0036296 | 25 | 12 | 18204 | 5365 |
FAS,SOD2,TXNRD2,ATP6V1G1,CYP1A1,CDKN1A,ATG7,TMEM199,EPO,ATP6V1A,POLB,CAV1 |
| 3.875e-02 | -3.25 | pyrimidine nucleoside metabolic process | biological process | GO:0006213 | 25 | 12 | 18204 | 5365 |
APOBEC3F,APOBEC3C,DTYMK,APOBEC3G,APOBEC3H,APOBEC3A,ERH,APOBEC3D,NT5C3A,UCKL1,APOBEC3B,DCTD |
| 3.875e-02 | -3.25 | activation of phospholipase C activity | biological process | GO:0007202 | 25 | 12 | 18204 | 5365 |
LPAR1,ADRA1A,HTR2A,S1PR4,PHB2,AVPR1B,LPAR2,PLCB2,PHB1,GNAQ,ITK,CD86 |
| 3.876e-02 | -3.25 | negative regulation of muscle cell differentiation | biological process | GO:0051148 | 73 | 29 | 18204 | 5365 |
CAV3,EZH2,HDAC5,MSX1,GSK3A,BMPR2,CCN3,PDCD4,MECP2,BMPR1A,TCF23,SMAD1,FOXP1,SMAD4,MIR21,PPARA,MIR221,HEY2,MIR590,TOMM70,PI16,MIR222,RGS2,G6PD,DKK1,CEACAM5,MIR100,HDAC3,XBP1 |
| 3.876e-02 | -3.25 | regulation of insulin receptor signaling pathway | biological process | GO:0046626 | 73 | 29 | 18204 | 5365 |
SNX5,SOCS3,NUCKS1,MIR107,NCK1,MSTN,ZNF592,OSBPL8,GKAP1,MIR195,SESN3,GSK3A,PRKCB,SRC,PTPN1,INPP5K,PRKCQ,GNAI2,IL1B,PID1,MIR1271,CTSD,GRB10,ADIPOR1,LEP,MZB1,NCOA5,PIP4K2C,PTPN11 |
| 3.876e-02 | -3.25 | positive regulation of phagocytosis | biological process | GO:0050766 | 73 | 29 | 18204 | 5365 |
FCN2,IL2RB,PLA2G5,FCER1G,IFNG,CALR,LYAR,IL15,CCL2,CD47,FCGR1A,RAB27A,IL2RG,FCGR2A,IL15RA,CD36,RAB31,CLEC7A,MIR183,HSPA8,MBL2,MIR17,MIR20A,PYCARD,SOD1,ITGA2,STAP1,FCGR2B,SFTPD |
| 3.876e-02 | -3.25 | fibrillar center | cellular component | GO:0001650 | 150 | 54 | 19108 | 5553 |
MTDH,ZNF174,KIT,HERC4,SMUG1,FHIT,UTP15,TCOF1,CD2BP2,GTF3C3,SMARCB1,CHCHD1,IP6K1,TOP1,NOP58,NOP53,PSPC1,PAFAH1B2,LIPA,TIMM13,ORC6,SAP30L,RERG,TAX1BP3,CDK7,DSN1,EXOSC8,MAP3K14,POLR1B,CDCA7L,CCR2,COIL,MRPL23,SNRPB2,APEX2,NHEJ1,IMP4,TRIM27,SPATA2,POLR2F,STN1,RPAIN,SMARCA5,DKC1,PAK6,BTBD10,ACACA,AGER,THAP1,RSAD2,NONO,TXNRD1,DDX46,CD2AP |
| 3.877e-02 | -3.25 | human chr7q22.3 | chromosome location | human chr7q22.3 | 22 | 9 | 26134 | 5823 |
CBLL1,SRPK2,SYPL1,RINT1,DUS4L,HBP1,BCAP29,GPR22,PIK3CG |
| 3.877e-02 | -3.25 | Pertussis | KEGG pathways | ko05133 | 76 | 34 | 7161 | 2463 |
IL6,IL1A,IL1B,TNF,IRF1,PYCARD,IL10,NLRP3,MYD88,NFKB1,TICAM1,GNAI2,JUN,TRAF6,MAPK10,SFTPA1,CFL1,CFL2,CXCL8,TLR4,IRF3,IL23A,TIRAP,IL12B,IL12A,CALML5,TICAM2,IRF8,IRAK4,FOS,LY96,GNAI3,C1QC,CD14 |
| 3.877e-02 | -3.25 | Pertussis | KEGG pathways | hsa05133 | 76 | 34 | 7161 | 2463 |
IL1B,IL1A,IL6,TNF,PYCARD,IRF1,IL10,NLRP3,MYD88,TICAM1,NFKB1,GNAI2,JUN,TRAF6,SFTPA1,MAPK10,CFL1,CFL2,TLR4,CXCL8,IL23A,IRF3,TIRAP,IL12B,IL12A,TICAM2,CALML5,IRAK4,IRF8,LY96,FOS,GNAI3,CD14,C1QC |
| 3.891e-02 | -3.25 | phosphatidylinositol phosphate phosphatase activity | molecular function | GO:0052866 | 30 | 14 | 18094 | 5411 |
SACM1L,INPP4A,INPP5K,INPPL1,OCRL,PIP4P1,PIP4P2,MTM1,MTMR6,FIG4,INPP5E,PTEN,PTPMT1,MTMR2 |
| 3.891e-02 | -3.25 | aldo-keto reductase (NADPH) activity | molecular function | GO:0004033 | 30 | 14 | 18094 | 5411 |
DHRS3,AKR7A2,KCNAB1,AKR1E2,RDH12,AKR1A1,AKR1B1,RDH10,SPR,AKR1C1,RDH11,AKR1C2,DHRS7,DHRS4 |
| 3.893e-02 | -3.25 | exon-exon junction complex | cellular component | GO:0035145 | 20 | 10 | 19108 | 5553 |
CASC3,MAGOHB,SRSF1,SAP18,UPF3B,THRAP3,PYM1,ALYREF,EIF4A3,MAGOH |
| 3.894e-02 | -3.25 | transporter regulator activity | molecular function | GO:0141108 | 146 | 54 | 18094 | 5411 |
LYNX1,STX8,YWHAH,STIM1,STX7,CFTR,KCNIP2,CAV3,SCN2B,ATP2B4,GLRX,FGF12,NPY2R,SNTA1,STX1A,CACNB3,CHP1,ADRB2,PCSK9,PACSIN3,LAMP2,KCNS1,CRISP1,STOM,NHERF1,SRI,CACNG3,FGF13,RANGRF,ARPP19,DPP10,AMIGO1,FXYD6,TMEM168,KCNMB1,PDE4B,DLG1,NPY,KCNMB2,VTI1B,KCNIP3,SCN3B,PRKCB,CAV1,FKBP1B,SUMO1,VAMP8,SCLT1,AKT1,SCN1B,KCNAB1,FKBP1A,GRM2,CHRNA7 |
| 3.912e-02 | -3.24 | DHX16 (DEAH-box helicase 16) | protein interactions | 8449 | 168 | 58 | 19454 | 5460 |
RAF1,CSNK1E,TRIM6,DHX38,TP53,MAP1LC3B,LBH,ESS2,CBX3,GABPB1,RHOBTB1,RPL31,TCEA2,KRAS,FOXN2,RIGI,IFI16,ERCC3,CSNK2A1,XPO1,DDRGK1,DDX23,LSM5,TOP1,WDR44,CDC5L,SUMO1,SNRNP27,FTH1,LMNA,RPA2,CPLX2,LSM2,TFIP11,RPA3,SIRT7,APPBP2,EP300,NUP50,MAVS,PSENEN,OIP5,FBXW7,COIL,AATF,MYC,ALKBH2,RBBP8,LSM6,RIT1,UBE2H,ZNF330,EZH1,SPCS1,SNRNP40,DEK,APEX1,TCEAL7 |
| 3.914e-02 | -3.24 | PABPC5 (poly(A) binding protein cytoplasmic 5) | protein interactions | 140886 | 136 | 48 | 19454 | 5460 |
STRBP,APOBEC3D,HPCAL1,PAIP2B,MRPL52,PABPC1,ZC3H11A,SRSF8,MEPCE,MOV10,HNRNPA1,APOBEC3F,TRA2A,ZCCHC9,MRPS9,SRSF1,PABPC1L,PRR3,PAIP1,BUD31,SRSF10,DKC1,EPHB6,ZC3H14,RBMS2,CFTR,LARP4B,ZNF326,RPL26L1,NUFIP2,NCOA5,TWNK,RPS15,TRA2B,STAU1,APOBEC3B,HNRNPC,RC3H2,PAIP2,ELAVL2,CASC3,RBM7,PPIG,PHAX,PRKRA,MATR3,IREB2,ESR2 |
| 3.914e-02 | -3.24 | ORF57 (ORF57) | protein interactions | 4961525 | 136 | 48 | 19454 | 5460 |
SF3B1,PRPF4,SLU7,DDX39B,DDX46,HELLS,RBM22,GTF2I,PPP1R2,ZC3H14,SNRPN,EIF4B,MFAP1,PAK2,GTF2F1,GTF2F2,EIF4A3,CTTN,CPSF1,SUB1,CDC73,RBM27,ZC3H11A,NKRF,CCT8,MAP1B,POLDIP3,HNRNPK,THRAP3,YTHDF2,RBM12,SRFBP1,BUD23,GTPBP1,IK,STIM1,DDX42,IGBP1,ALYREF,THOC2,SLAIN2,MIF,HNRNPL,HNRNPA1,IFI16,PRPF19,TAF7,CLP1 |
| 3.914e-02 | -3.24 | ITGB5 (integrin subunit beta 5) | protein interactions | 3693 | 136 | 48 | 19454 | 5460 |
FHL3,EWSR1,TRIM63,KRAS,CLEC2B,TOP3B,ITGB5,RAB4A,RAC2,ADAM21,CD1A,HNRNPL,ARF6,GAPDH,LRRC4,PDIA3,POR,SPP1,MTDH,APPBP2,BCL6,ITGAV,STX7,ST8SIA4,CFTR,SEC62,TMEM106A,ATG16L1,CLDN4,FDFT1,ZNF655,ALB,CYB5R3,PLP1,GXYLT1,ST8SIA5,RHOJ,ZBTB17,RAB11A,CUL3,EPS8,MYC,RAB2A,KLK5,EPHA2,RHOB,ATP1B3,SNTA1 |
| 3.915e-02 | -3.24 | choriocarcinoma | COSMIC cancer mutations | choriocarcinoma | 15 | 8 | 16828 | 4835 |
IDH2,IDH1,JAK2,KRAS,KIT,HRAS,SF3B1,TERT |
| 3.915e-02 | -3.24 | large_intestine-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-adenoma-tubulovillous | 15 | 8 | 16828 | 4835 |
PIK3CA,STK11,SMAD4,PTEN,CTNNB1,KRAS,FBXW7,PIK3R1 |
| 3.915e-02 | -3.24 | parietooccipital | COSMIC cancer mutations | parietooccipital | 15 | 8 | 16828 | 4835 |
TP53,CTNNB1,IDH2,MSH6,IDH1,CDKN2C,EZH2,PTEN |
| 3.915e-02 | -3.24 | large_intestine-colon-adenoma-villous | COSMIC cancer mutations | large_intestine-colon-adenoma-villous | 15 | 8 | 16828 | 4835 |
PIK3R1,PTEN,SMAD4,FBXW7,STK11,CTNNB1,KRAS,PIK3CA |
| 3.915e-02 | -3.24 | large_intestine-rectum-adenoma-villous | COSMIC cancer mutations | large_intestine-rectum-adenoma-villous | 15 | 8 | 16828 | 4835 |
PIK3R1,PTEN,SMAD4,FBXW7,STK11,KRAS,CTNNB1,PIK3CA |
| 3.915e-02 | -3.24 | large_intestine-colon-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-colon-adenoma-tubulovillous | 15 | 8 | 16828 | 4835 |
PIK3CA,KRAS,CTNNB1,STK11,FBXW7,SMAD4,PTEN,PIK3R1 |
| 3.915e-02 | -3.24 | thymus-thymic_carcinoma | COSMIC cancer mutations | thymus-thymic_carcinoma | 15 | 8 | 16828 | 4835 |
PIK3CA,PTEN,MET,HRAS,KIT,KRAS,TP53,AKT1 |
| 3.915e-02 | -3.24 | ovary-germ_cell_tumour-yolk_sac_tumour | COSMIC cancer mutations | ovary-germ_cell_tumour-yolk_sac_tumour | 15 | 8 | 16828 | 4835 |
SMAD4,IDH2,DICER1,PPP2R1A,IDH1,KIT,CTNNB1,KRAS |
| 3.915e-02 | -3.24 | liver-carcinoma-fibrolamellar_carcinoma | COSMIC cancer mutations | liver-carcinoma-fibrolamellar_carcinoma | 15 | 8 | 16828 | 4835 |
NFE2L2,TERT,IDH1,IDH2,FBXW7,CTNNB1,KRAS,TP53 |
| 3.915e-02 | -3.24 | fibrolamellar_carcinoma | COSMIC cancer mutations | fibrolamellar_carcinoma | 15 | 8 | 16828 | 4835 |
IDH1,FBXW7,IDH2,KRAS,CTNNB1,TP53,NFE2L2,TERT |
| 3.915e-02 | -3.24 | large_intestine-adenoma-tubular | COSMIC cancer mutations | large_intestine-adenoma-tubular | 15 | 8 | 16828 | 4835 |
PIK3CA,STK11,SMAD4,PTEN,KRAS,CTNNB1,FBXW7,PIK3R1 |
| 3.915e-02 | -3.24 | villous | COSMIC cancer mutations | villous | 15 | 8 | 16828 | 4835 |
PIK3CA,CTNNB1,KRAS,STK11,FBXW7,SMAD4,PTEN,PIK3R1 |
| 3.915e-02 | -3.24 | tubulovillous | COSMIC cancer mutations | tubulovillous | 15 | 8 | 16828 | 4835 |
SMAD4,FBXW7,PIK3R1,PTEN,PIK3CA,STK11,CTNNB1,KRAS |
| 3.921e-02 | -3.24 | clathrin-coated pit | cellular component | GO:0005905 | 77 | 30 | 19108 | 5553 |
HSPD1,NECAP1,AP2S1,LRP3,DNM2,LRP12,CTTN,AP2M1,ATAT1,BMPR2,TBC1D5,OCRL,SH3BP4,NECAP2,MYO6,LDLR,VLDLR,AP2A1,AP1S2,TF,LRP10,PICALM,ACKR3,SNAP91,RAB35,TFRC,CCDC32,FCHSD2,SGIP1,FCHO2 |
| 3.921e-02 | -3.24 | ZBTB33 (zinc finger and BTB domain containing 33) | protein interactions | 10009 | 117 | 42 | 19454 | 5460 |
SFN,CUL3,FOXA3,AKT1,CTNNB1,KLHL22,AR,YWHAG,CFL1,YWHAZ,TXNIP,TUBG1,PFDN4,GYS1,ZBTB33,FBLN5,CCNF,PHF21A,FOXP3,MIF,SUMO2,SUMO3,RHOH,ZNF576,EGLN3,NOTCH2,TP53,LMNA,PML,TRIM10,RPA3,EP300,HSPA8,SF3B1,KPNA2,SGF29,HDAC3,HUWE1,KDM1A,RNF41,PCGF6,CTNND1 |
| 3.921e-02 | -3.24 | GTPBP1 (GTP binding protein 1) | protein interactions | 9567 | 117 | 42 | 19454 | 5460 |
FUBP3,PHB1,TNIK,CCNF,EEF2KMT,CORO1C,FZR1,CAND1,CDC5L,CUL3,MYC,MOV10,KARS1,DDRGK1,DIS3L,COPS5,CPEB1,SNRNP70,UBE2H,STK11,LSM14A,RPA3,RAB27A,HSPA8,STAU1,UFL1,NF2,RIGI,DUSP19,RAD21,YTHDF2,E2F4,TP53,ATG16L1,TOP3B,RAF1,TULP3,CER1,QTRT2,CHAMP1,RPA2,SCLT1 |
| 3.921e-02 | -3.24 | LAMC1 (laminin subunit gamma 1) | protein interactions | 3915 | 117 | 42 | 19454 | 5460 |
HSPA5,SKP1,CAMKV,GPIHBP1,OPA3,HSPA8,DNAJC3,TMEM106B,NCR3,DISC1,TSHR,SNAPIN,MAP1LC3B,CD2AP,CARTPT,LGR4,CCL3,B3GNT2,RAF1,PI15,TANK,MAT2B,CCT7,DHX15,VIRMA,ESR2,SNX2,LGALS3,PRNP,PSMC5,TSG101,SEC61B,ZDHHC15,CALU,TUBG1,SDF2L1,YWHAZ,DNAJC10,GGH,PDIA3,CFC1,CUL3 |
| 3.923e-02 | -3.24 | ribonucleoside diphosphate metabolic process | biological process | GO:0009185 | 76 | 30 | 18204 | 5365 |
IER3,PGM1,CMPK1,AK3,BAD,UCP2,CASK,RRM1,AK2,NUDT9,GAPDH,NUDT18,AK5,PGK1,LIPA,MPP1,FKRP,UMPS,PFKFB2,DLG1,BPGM,ENO2,NUDT5,LDHA,OGDHL,GUK1,ENO1,ENTPD4,PGAM1,HTR2A |
| 3.926e-02 | -3.24 | Vaccinia Virus protein VP39 | gene3d domains | 3.40.50.150 | 115 | 42 | 14470 | 4137 |
METTL6,PRMT6,TRMT5,LRTOMT,INMT,METTL15,CSKMT,GAMT,GSTCD,TMT1A,PCMTD1,EEF2KMT,FTSJ3,NTMT1,COMTD1,ASMT,TMT1B,MRM2,PCMTD2,PRMT2,METTL2A,MEPCE,FTSJ1,TRMT61A,COMT,EEF1AKMT3,VCPKMT,SRM,METTL26,BUD23,GNMT,ETFBKMT,PRMT5,METTL18,HNMT,HENMT1,TRMT1L,METTL21A,TFB1M,LCMT1,METTL22,TRMT11 |
| 3.932e-02 | -3.24 | regulation of T cell differentiation | biological process | GO:0045580 | 185 | 66 | 18204 | 5365 |
BTN2A2,FGL2,SMARCE1,DUSP10,KLHL25,BATF,NKAP,ACTL6A,SASH3,HMGB1,SYK,JUNB,CD83,IL18,PRDX2,PNP,FOXP3,BCL6,TESPA1,CD86,IL2RG,TOX,ACTL6B,ACTB,EP300,CD2,VSIR,SOS2,IFNG,IL12B,CD46,TGFBR2,IRF4,CCR2,IL2,CCL19,MIR30B,IFNA2,MIR21,SOD1,LILRB4,RHOH,CTLA4,SMARCD3,XBP1,SOCS5,RUNX1,IRF1,NLRP3,ZBTB16,IL4,IL23A,RAG1,CD28,CBFB,CD80,BAD,IL7,DROSHA,IL2RA,IL15,IFNB1,PRELID1,RC3H2,SMARCB1,WNT10B |
| 3.932e-02 | -3.24 | carbohydrate homeostasis | biological process | GO:0033500 | 216 | 76 | 18204 | 5365 |
MBD5,PLSCR3,PIK3CA,KCNB1,ADIPOQ,RRAGA,UCP2,ICAM1,SMAD3,RAF1,CRTC2,SESN3,TWNK,IL6,IGF1R,DBH,LEPR,BGLAP,CLTRN,GPX1,MIR15A,ADIPOR2,GCLC,KCNJ11,RMI1,PPP3CA,INPP5K,AKT1,RAB11B,DHPS,FOXA3,PTPN11,AGER,STK11,LEP,ADIPOR1,LRRC8A,SMAD4,SELENOT,SIN3A,PAX6,FABP5,FOSL2,FKBP1B,CRY1,MIR16-1,CMA1,MIRLET7G,TRA2B,CYP11B1,NUCKS1,BAD,CMKLR2,LRRC8D,OAS1,CAV3,PCK2,PIK3R1,XBP1,CYB5R4,MIR320A,PRCP,PIK3R2,SESN2,SMAD2,SLC29A1,CYP7A1,SLC16A1,OPRK1,CCDC186,PPARG,CARTPT,NCOA5,MIR146A,NPTX1,CNR1 |
| 3.933e-02 | -3.24 | MAP3K1 (mitogen-activated protein kinase kinase kinase 1) | protein interactions | 4214 | 152 | 53 | 19454 | 5460 |
RPL4,STK38,UBE2K,UBE2D3,TRIM5,CD40,IMPACT,DVL2,BAP1,UBAP1,GSTP1,MAP2K1,TOM1L2,UBE2W,VIRMA,DYRK1A,RNF141,TAB1,PSMD4,UBE2I,UBASH3B,CHRM5,NFKBIA,APEX2,DNAJB6,BRCA1,YWHAZ,UFD1,CEP85,RPS13,TOM1,RBCK1,HNRNPK,BAALC,CCDC69,RNF126,HGS,CRELD1,MINDY3,UBE2V1,FAF2,TRAF2,JUN,TP53,RAF1,DCUN1D1,DENND6B,UBE2D1,IKBKB,XPO1,YWHAG,DNAJB2,DYRK1B |
| 3.933e-02 | -3.24 | KRT5 (keratin 5) | protein interactions | 3852 | 152 | 53 | 19454 | 5460 |
INPPL1,DDX39B,BAP1,NMRAL1,PIK3R2,ADRB2,CFTR,METTL14,HEXIM1,PIH1D1,WTAP,RNF208,EIF4A3,AP2M1,ALB,UBASH3B,NDN,MTM1,VIRMA,MYC,CUL3,CUL2,BTF3,SPOP,UBE2H,FAF1,UBE3A,NEDD8,TNF,TRIM37,MEPCE,UBE2A,FBP1,TP53,INSIG2,SOX2,LGR4,EZH2,RND3,RNF8,EFNA3,CAND1,FZR1,DCUN1D1,SUMO2,MARCHF5,HDAC6,HNRNPA1,COPS5,TRAF6,SHC1,CBL,MAGOH |
| 3.934e-02 | -3.24 | phagocytic vesicle membrane | cellular component | GO:0030670 | 80 | 31 | 19108 | 5553 |
SNAP23,RAC2,RAB23,TAPBP,TLR2,B2M,RAB9B,MCOLN1,RAB9A,ATP6V0B,RAB22A,SEC22B,SLC15A2,RAB5A,TLR6,VAMP7,ATP6V0E1,CALR,OCRL,RAB11B,RAB32,VAMP8,PIP4P1,PIP4P2,RAB31,RAB8B,DNM2,TLR1,LAMP2,VAMP3,SLC48A1 |
| 3.942e-02 | -3.23 | membrane insertase activity | molecular function | GO:0032977 | 17 | 9 | 18094 | 5411 |
EMC6,TIMM10,EMC8,EMC2,EMC1,EMC9,MTCH2,EMC10,EMC4 |
| 3.942e-02 | -3.23 | phosphate transmembrane transporter activity | molecular function | GO:0005315 | 17 | 9 | 18094 | 5411 |
UCP2,SLC25A10,SLC20A2,ANKH,SLC25A24,SLC20A1,SLC25A23,SLC25A3,SLC37A4 |
| 3.945e-02 | -3.23 | antimicrobial humoral response | biological process | GO:0019730 | 139 | 51 | 18204 | 5365 |
CXCL3,F2,CCL19,CXCL13,CCL1,CCL25,WFDC5,RARRES2,LEAP2,FAM3A,CCL21,SLPI,REG1A,LYZ,CCL4L1,CCL18,GAPDH,SEMG2,CCL2,H2BC11,NCR3LG1,CXCL10,CXCL14,RPL39,RNASE4,REG1B,WFDC13,CCL20,CXCL1,JCHAIN,CCL8,CCL11,CCL23,CCL3,H2BC12,TF,CCL24,CXCL11,CAMP,PI3,DEFB1,CCL17,SPAG11B,XCL1,FAU,RNASE6,CX3CL1,CCL5,CXCL8,CXCL9,ROMO1 |
| 3.954e-02 | -3.23 | phospholipid biosynthetic process | biological process | GO:0008654 | 241 | 84 | 18204 | 5365 |
VAC14,PIK3CG,INPP4A,ABHD5,DPM2,FITM1,IMPA2,IP6K1,SOCS4,PCYT1B,INPP5K,AGPAT5,CISH,TMEM38B,MTMR2,ISYNA1,ORMDL3,GGPS1,PGAP2,PGAP3,SOCS2,PGAP4,GNPAT,HYCC1,SERINC1,INPP5E,CDIPT,AGPAT1,MTMR6,GPAM,FIG4,OSBP,GPAA1,PIK3R3,ABHD4,PIK3CA,PLAAT3,FITM2,SGMS1,PIGC,PLSCR3,MTM1,TAMM41,MVD,PGS1,PTDSS1,LPCAT3,PLSCR1,SRD5A3,ETNK2,PIGY,OCRL,PIP4K2C,BECN1,HYCC2,PIGK,SLA2,HDHD5,SELENOI,CHKB,SLC30A5,DOLK,PIK3R2,SOCS5,SGMS2,DHRS7B,BPNT2,ORMDL1,PIK3R1,PTPMT1,HEXB,NUS1,PIGW,TAFAZZIN,PIGA,HMGCS1,ACP6,FABP5,SPHK2,SACM1L,SOCS3,PTEN,INPPL1,PIP5K1A |
| 3.956e-02 | -3.23 | Golgi apparatus subcompartment | cellular component | GO:0098791 | 385 | 128 | 19108 | 5553 |
NSFL1C,RGP1,MOB4,RAB31,YIPF4,GAL3ST4,B4GALT3,VAMP3,B4GALT6,TMEM59,CHID1,TMEM165,STX16,VAMP7,AZIN2,GOLGA7,PICK1,AP1S2,SGMS1,CHST1,GPR89A,STX8,GOLPH3L,GOSR1,B4GALT7,SAR1B,CLVS2,PLEKHA8,GGTA1,COG1,FAM91A1,PLEKHJ1,OSBP,PREPL,MYO1B,APH1A,CCDC186,YIPF5,SCAMP5,CHST7,FUT1,WDR11,TRAPPC4,ARFIP1,SNAP25,GOLGA5,BACE1,MGAT4B,CSGALNACT2,PSENEN,RAB29,CHPF2,MS4A7,ATP8A1,SCAMP2,CHST2,RHOBTB3,ST3GAL4,CHPF,RAB13,USP6NL,VAMP2,RAB9A,TMEM87A,NDST1,FCMR,CD2AP,SYS1,BOK,ATG9A,OPTN,ST6GAL1,ARFGEF1,CLBA1,CLVS1,SLC30A5,ATP2C1,BPNT2,AFTPH,ST3GAL2,CSGALNACT1,TRAPPC6B,NSG1,INPP5K,SCFD1,TMEM115,VRK1,OCRL,MGAT4A,GCC1,RAB11A,GALNT1,FUT8,VCPIP1,FUT9,MARCHF9,TMED3,RAB14,LAP3,RAB32,LYPLA2,STX6,SLC39A9,VPS54,CLIP3,TAS2R16,TOM1L1,PHETA2,ZDHHC14,SLC66A2,STX10,B4GALT1,DPY30,TRAPPC6A,INPP5E,RAB30,ST3GAL1,LYSET,GALNT2,AP1M1,MME,ATL1,ARL5B,SLC30A7,BECN1,MARCHF4,FURIN,RAB6A |
| 3.961e-02 | -3.23 | KDM5B (lysine demethylase 5B) | protein interactions | 10765 | 92 | 34 | 19454 | 5460 |
EZH2,PAX9,MTA2,TAF2,MTA3,KDM1A,KRAS,RBBP7,UFL1,NUCKS1,MBD3,RIGI,PRPF4,HDAC5,KLF10,YWHAZ,FBXW11,CHTOP,YWHAB,CSK,MYC,LMO2,PCNX1,FOXC2,YWHAG,YWHAH,RBM15B,AR,RBBP4,CDC20,USP38,VIRMA,GTF2A1,RB1 |
| 3.961e-02 | -3.23 | DPF3 (double PHD fingers 3) | protein interactions | 8110 | 92 | 34 | 19454 | 5460 |
BCL7B,SNIP1,SMARCD3,DNAJB4,EP300,DDIT3,LCN1,H3C1,PYGB,SS18,ACTL6A,CFTR,LMNA,SMARCB1,TFB1M,CSNK1A1,AIFM1,CSNK2B,BRD9,PYGM,SPPL3,DBT,TECR,VIRMA,NFKB1,MYC,BCL7C,SMARCE1,CSNK2A1,ACTL6B,SMAD4,AHSA1,XPOT,LYZ |
| 3.962e-02 | -3.23 | ADH_SHORT | prosite domains | PS00061 | 35 | 15 | 12186 | 3388 |
CBR3,HSD11B1,CBR4,DHRS11,HSDL2,DHRS7,HSD17B10,HSD17B8,HSD17B3,HSD17B6,DHRS4,KDSR,HSD17B1,DHRS7B,RDH10 |
| 3.971e-02 | -3.23 | GPR161 (G protein-coupled receptor 161) | protein interactions | 23432 | 29 | 13 | 19454 | 5460 |
MOV10,CREBBP,COMT,RAB11A,PRKACB,RTN4,CCR2,BRCA1,GOLGA5,FBXW11,GPR35,GNB4,EFNA5 |
| 3.971e-02 | -3.23 | LTBP3 (latent transforming growth factor beta binding protein 3) | protein interactions | 4054 | 29 | 13 | 19454 | 5460 |
GORASP2,HBEGF,CUL3,TOP3B,TGFB2,ZDHHC15,ITGB5,TGFB3,NUFIP2,DNAJC10,DYRK1A,APEX1,PIK3R2 |
| 3.971e-02 | -3.23 | E2F5 (E2F transcription factor 5) | protein interactions | 1875 | 29 | 13 | 19454 | 5460 |
E2F6,BIRC5,TFDP2,XPO1,GMNN,CDKN1A,MYC,CREBBP,E2F4,PCGF6,EP300,RB1,SMAD3 |
| 3.971e-02 | -3.23 | DCLK2 (doublecortin like kinase 2) | protein interactions | 166614 | 29 | 13 | 19454 | 5460 |
KLHL15,ENO1,BTG3,RNF41,APEX1,ZBTB5,TSC22D3,HNRNPL,KRAS,YWHAG,YWHAH,YWHAB,HSP90AA1 |
| 3.971e-02 | -3.23 | C4BPB (complement component 4 binding protein beta) | protein interactions | 725 | 29 | 13 | 19454 | 5460 |
DCTN4,GGCX,TP53,PROS1,KLHL22,MRPL10,LAMB2,ERLEC1,DCTN6,ZNF655,ACTR1B,DCTN3,OLFM2 |
| 3.971e-02 | -3.23 | SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor) | protein interactions | 55164 | 29 | 13 | 19454 | 5460 |
EXOSC4,RUVBL2,HAPSTR1,DKC1,RUVBL1,DGCR8,KRAS,XPO1,CUL3,AKT1,MYC,RIT1,CCL18 |
| 3.971e-02 | -3.23 | TRPC1 (transient receptor potential cation channel subfamily C member 1) | protein interactions | 7220 | 29 | 13 | 19454 | 5460 |
FKBP4,BMPR2,STIM1,TRPC1,H2BC9,MX1,MDFI,CAV1,HOMER1,STAU1,GRM1,HOMER3,GRIA1 |
| 3.971e-02 | -3.23 | MACIR (macrophage immunometabolism regulator) | protein interactions | 90355 | 29 | 13 | 19454 | 5460 |
TRAF1,SLA2,AVPI1,PNMA1,YWHAZ,STK16,LRRC57,YWHAB,MDFI,EXOSC8,YWHAH,XPO1,YWHAG |
| 3.971e-02 | -3.23 | AP5Z1 (adaptor related protein complex 5 subunit zeta 1) | protein interactions | 9907 | 29 | 13 | 19454 | 5460 |
HSPA8,BAG2,IRF2,CXCR4,STUB1,RIGI,TUSC2,NPTN,BAG3,MDFI,AP5S1,PRKAB1,SAYSD1 |
| 3.971e-02 | -3.23 | BNIP5 (BCL2 interacting protein 5) | protein interactions | 389384 | 29 | 13 | 19454 | 5460 |
YWHAG,WDR83,CDC16,BAX,ANAPC4,TBC1D17,BCL2L1,YWHAZ,DCAF16,MMACHC,GNPAT,TCOF1,GRPEL1 |
| 3.971e-02 | -3.23 | LCMT2 (leucine carboxyl methyltransferase 2) | protein interactions | 9836 | 29 | 13 | 19454 | 5460 |
HSPA8,DNAJB4,HAPSTR1,RPA3,ACTA2,ZBED1,NUDCD3,TUBA1A,ACTN4,VPS26A,DNAJC7,CCT2,RPA2 |
| 3.971e-02 | -3.23 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | biological process | GO:0006890 | 50 | 21 | 18204 | 5365 |
BICD2,KIF1C,ARF4,RAB6B,STX18,PICK1,SCFD1,SEC22B,TAPBP,ARCN1,KDELR1,KDELR2,USE1,COPE,RAB6A,GOLPH3L,TMEM115,RER1,PITPNB,COPZ2,RINT1 |
| 3.980e-02 | -3.22 | ZNF512B (zinc finger protein 512B) | protein interactions | 57473 | 194 | 66 | 19454 | 5460 |
ELF5,TRIM36,LMNA,TOX4,KLF12,CREBZF,SPTBN1,COIL,MBD3,NUP50,LMNB1,ANAPC15,DNAJC8,AR,RSPH1,CDC123,NIBAN2,SMARCA5,TRAF1,APEX1,RBBP4,SIAH1,YES1,ZMYM2,ZNF330,MTA2,EZH2,IRF8,CBX3,SMAD1,SAP30,MTA3,SUPT5H,PHF1,UBE2A,VWF,RPS27A,TNKS2,PAX6,DPM2,H3C1,RBBP7,LAMB2,TOM1,ASF1A,KLF10,FHL3,RPL31,ZYX,LHX2,DDX23,KDM2A,DROSHA,MDFI,DPY30,PEG10,OS9,SPPL3,BRMS1L,SHPRH,EED,MYBL2,GATAD1,CCDC71,SIN3A,UBP1 |
| 3.982e-02 | -3.22 | positive regulation of DNA-templated transcription | biological process | GO:0045893 | 1667 | 523 | 18204 | 5365 |
MED11,HINFP,S100A10,GABPA,HRAS,ZNF304,GTF2A2,BATF,FGF7,HMGB1,ZNF770,PLAC8,INO80C,SSBP4,MSX1,RUVBL1,PHB1,ING1,ACTB,HMGA1,DDRGK1,CRLF3,TNF,RBBP7,LBH,NAA15,CX3CL1,RAF1,ARMCX3,IL10,H2AZ1,YAF2,RBPJ,SF3B1,IRF4,FOXC2,PLSCR1,NEUROG2,BRD3,TFDP2,ZBED4,NLRP3,CEBPG,ACVR1,LDB1,ILK,FBXW11,RB1,CITED1,OGG1,NFYA,CXCL10,SUPT5H,ZNF593,MED4,CDK9,NDN,USP16,KLF4,ZBED3,PAX9,ARF4,JADE1,TFPT,DNAJC2,TLR4,DDIT3,TRIM27,P2RY1,TRIP4,ZNF473,HELT,ZNF574,SIX5,ACSS2,RAP2C,CSRNP3,VGLL2,MITF,VPS72,ITGA6,SOST,UBP1,NCBP2,ACTL6B,TAF7,TP53,SP1,PPARG,CCNA2,EPCAM,RNF20,TRIM52,JUP,RNF187,ZNHIT1,PGR,RHOG,FOXJ3,ESR2,NFYB,LHX2,EZH1,RFXAP,HEXB,GTF2I,IER2,NR4A2,EPO,LUM,ZNF668,EGR1,IKBKB,MYRF,TGFB1I1,TRIM44,CNOT7,TRIM15,STAT6,CDH13,MBD3,PRDM4,HAND2,MTDH,CREBBP,PROX1,ZNF345,ZBTB18,ADRB2,GREM1,HCFC2,TRIM37,MSL2,IRF2,SOX2,WASL,NFKBIB,ABHD14B,DHX9,DYRK1A,HOXB1,SPP1,FGF10,RERE,ZBTB38,TF,RPRD1B,IRF6,SCAND1,TRIM8,NCK1,NOTCH2,RASL11A,MAP2K3,IL1A,TGFB2,TOPORS,PICALM,MAFG,LITAF,CDK7,CNOT6,SF3B5,RBM23,HOXC4,TRIM22,SUB1,TADA3,NFE2,MTF1,SOX9,STAT2,AIP,BAZ1B,FOSL2,PAGR1,PRKCB,MAP2K1,CTBP1,HDAC5,SHC1,PRMT2,IRF8,NUCKS1,COPS5,SETD3,ANKRD49,IL5,EDF1,RGMB,SMAD1,ZBED1,TLR7,IRF7,CDC5L,ACTN4,NR1I2,KDM1A,RIT2,RFX4,SMAD5,GTF2F2,BARX2,HEY2,MAP3K12,IRF3,MED21,NFIL3,SETD7,TNFSF8,KLF12,YWHAH,HNF1B,PSRC1,INPP5K,BCL10,APLN,RPS6KA4,LILRB1,OSR2,MYC,RTRAF,SFRP1,CREB1,AGO1,NUPR1,MARS1,CASK,RORB,TLR3,MOSPD1,SSBP2,DLX1,WWP2,PELP1,ZGLP1,CD4,PSEN1,EGR2,NKRF,CD81,MDC1,RUNX1,HSPA5,IRF9,TAF2,MYD88,SMAD2,ILF2,SLC38A3,BRCA1,IL4,BUD31,TAF5L,PIM2,CBFB,TADA1,CD28,MEF2C,ING2,SUPT7L,RUVBL2,MSTN,GPBP1L1,MEPCE,IFNB1,ZBTB17,MAVS,TNKS,KANSL3,MEAF6,FOXA3,NKX3-1,ATF3,NME2,NOG,TESC,PKNOX1,EAF2,SGF29,CREB3,MED22,TRIM5,PITHD1,NR1I3,MED10,KLF10,CD40,MED30,TRIM32,HNRNPD,WNT2,UBE2L3,TAF9,MED9,MED23,TRIM62,SERTAD1,BIRC2,YES1,PCBD1,NIF3L1,SMAD3,TCEA1,CRTC2,CSRNP1,RNF10,AKAP8L,PIAS1,TBK1,STAT5A,PLAGL1,RNF40,CD38,MRPL12,TLR2,TRAF6,NDP,ZNF287,SERTAD3,NFKB1,PIH1D1,TERT,SUPT3H,HLF,BMPR1B,TFCP2,IRF2BPL,FOS,HCLS1,CHCHD2,PSMC5,ARL2BP,POU1F1,NUP62,WBP2,ZNF175,TFEB,TRIM21,ATF4,HNRNPK,SQSTM1,IL18,ELK3,SMARCA5,ZNF609,STK16,MEF2A,SUPT4H1,ETV6,IL17F,TAF10,MED17,APEX1,SOX14,ZNF319,ELK4,IFI16,DEK,NIBAN2,LMO3,FZD4,RFXANK,CAMK1,ACTR2,PIK3R1,NR2E1,SETD4,KLF1,PIK3R2,PQBP1,IRF1,AFAP1L2,UTP15,OSM,IL23A,MTA2,BMPR2,VEGFA,TFE3,CCAR1,SMAD9,NFE2L2,SOX3,BMPR1A,FGF23,MECP2,SMARCB1,BCL9,FUBP3,SERTAD2,INO80E,SMAD4,CEBPE,UBE2V1,WNT7A,PPP3CA,AKT1,DYRK1B,TGFB3,IL1B,RBBP4,CTNNB1,VDR,MAX,HYAL2,BACH1,TEF,MT3,CREB3L4,NEUROD6,TOX,NFKBIA,IGF1,EP300,SNX5,ENY2,NAA16,WDR77,KARS1,SIRT7,SS18,CDK12,PSMC3,CYTL1,IL2,RRN3,HNRNPAB,TRIM24,AR,CREBZF,AATF,XBP1,LMO4,MET,MLLT11,PID1,DVL2,CDK5RAP3,KPNA6,GSK3A,RGMA,ATF1,E4F1,MORF4L1,MED31,JAK2,LMO2,TAF11,CAND1,FGF1,NR1H2,STAT1,LRP6,HAX1,MTA3,E2F4,ZNF263,NEUROD2,PPARA,RXRG,SMARCE1,CXXC1,JUNB,OTX2,ACTL6A,PPP1R12A,PRL,JUN,HAS3,CD274,FOXP3,DMAP1,TP53INP1,EFCAB7,IL6,GTF2F1,ID4,RFX5,ZNF267,CD86,ZFP64,SOX21,THRAP3,ZNF513,ELF1,RNASEL,LDB2,RNF14,UBE3A,CDC73,MEF2B,ZNF507,ECD,TLR9,PLCB1,SMARCD3,DNM2,HDAC3,MLLT6,ZBTB16,MYBL2,ZNF24,RGCC,CREBL2,UCN,GABPB1,CD80,MED27,TP53INP2,GTF2A1,FOXD3,TCF21,POU5F1,MAD2L2,LYAR,ELK1,SMYD3,SSBP3,PAX6,RIGI,MED29,WNT10B |
| 3.988e-02 | -3.22 | chemotaxis | biological process | GO:0006935 | 345 | 117 | 18204 | 5365 |
CCL5,CXCL8,LPAR1,CXCL9,FCER1G,IL6,CCL17,SEMA6C,PPIA,CCL3,RAC2,MIF,ITGAV,MSMP,ACKR3,ANGPT1,PPIB,SCG2,CCL8,CCL11,MACO1,CXCL14,VEGFC,PIK3CG,PDE4B,SRP54,TPBG,LGALS3,CCL27,VEGFA,SEMA7A,EFNA5,GAB1,PLGRKT,CCL1,RHOG,LECT2,GPNMB,PRKCQ,SEMA4C,FLRT2,JAML,CXCL13,CXCL3,HBEGF,PTN,CCR3,PLP2,DPEP1,XCL1,IL10,TGFB2,CX3CL1,CX3CR1,DEFB1,CCN3,FGF10,RALA,CMTM7,CCL24,CXCL11,CXCR6,CCR4,FGF7,HMGB1,CH25H,SYK,IL1B,CXCR1,CCL23,EPHA2,SERPIND1,CXCL12,CCR7,FOLR2,CXCR4,S100A8,SEMA5A,CCR6,SEMA3C,ELMO2,HRAS,CXCL1,CREB3,CCL20,CCL2,PIP5K1A,CXCL10,CCL28,NRP1,CHGA,MAP2K1,CCR1,CCL18,L1CAM,DEFB114,CCL4L1,CKLF,MET,CCL21,CXCR3,RPL13A,FLRT3,SLC12A2,KIT,CCL25,CCR5,RARRES2,CCR2,SFTPD,CCL19,DPP4,LRTM2,CRKL,ADGRE2,NINJ1,RAB13 |
| 3.998e-02 | -3.22 | lipopolysaccharide binding | molecular function | GO:0001530 | 41 | 18 | 18094 | 5411 |
CAMP,DEFB114,CASP4,NLRP6,LY96,BPIFA2,H2BC11,HMGB1,TLR2,HSPD1,F2,PSMA1,CD14,ZRANB2,PSMB4,TLR4,DROSHA,NINJ1 |
| 3.998e-02 | -3.22 | HMBS (hydroxymethylbilane synthase) | protein interactions | 3145 | 18 | 9 | 19454 | 5460 |
GSK3A,PICK1,HNRNPA1,EWSR1,YTHDF2,PDIA3,ZDHHC17,UMPS,TP53I3 |
| 3.998e-02 | -3.22 | Gnb1 (guanine nucleotide binding protein (G protein), beta 1) | protein interactions | 14688 | 18 | 9 | 19454 | 5460 |
CCT8,CCT5,HSPD1,GNG12,TCP1,CCT2,CCT7,PFDN1,PDCL |
| 3.998e-02 | -3.22 | GNA14 (G protein subunit alpha 14) | protein interactions | 9630 | 18 | 9 | 19454 | 5460 |
DNAL4,PMAIP1,DUSP22,CCR1,NRP1,OPRL1,CXCR1,TFCP2,ADRB2 |
| 3.998e-02 | -3.22 | SALL3 (spalt like transcription factor 3) | protein interactions | 27164 | 18 | 9 | 19454 | 5460 |
S100B,VRTN,SOX2,ING1,TEX19,RBBP4,CRBN,PPIA,POU5F1 |
| 3.998e-02 | -3.22 | HTRA3 (HtrA serine peptidase 3) | protein interactions | 94031 | 18 | 9 | 19454 | 5460 |
CCL4L1,SPCS3,KRAS,TNFSF8,ROCK2,HEXIM1,SERPINB1,ROCK1,MAEA |
| 3.998e-02 | -3.22 | AP5S1 (adaptor related protein complex 5 subunit sigma 1) | protein interactions | 55317 | 18 | 9 | 19454 | 5460 |
MORF4L1,ACBD6,COPS7A,LDLR,NHERF1,COPS7B,TNFSF8,COPS4,AP5M1 |
| 3.998e-02 | -3.22 | Fbxl16 (F-box and leucine-rich repeat protein 16) | protein interactions | 214931 | 18 | 9 | 19454 | 5460 |
SKP1,DDX1,RPL35,RPS29,RPS9,RPL15,PPP2R1A,PPP2CB,XRCC5 |
| 3.998e-02 | -3.22 | MAP3K15 (mitogen-activated protein kinase kinase kinase 15) | protein interactions | 389840 | 18 | 9 | 19454 | 5460 |
SYCE3,HAPSTR1,YWHAH,TMX3,YWHAZ,METTL14,SSR1,CHCHD4,HSP90AA1 |
| 3.998e-02 | -3.22 | SNX25 (sorting nexin 25) | protein interactions | 83891 | 18 | 9 | 19454 | 5460 |
B4GAT1,VIRMA,TSPAN5,SIX5,APH1A,VAPB,NDUFC2,DDX39A,TSPAN15 |
| 3.998e-02 | -3.22 | SEC14L1 (SEC14 like lipid binding 1) | protein interactions | 6397 | 18 | 9 | 19454 | 5460 |
VIRMA,CDH13,NPTN,NCR3LG1,C2CD2,CEP70,HCST,LAMP3,PGAM1 |
| 3.998e-02 | -3.22 | CSF2 (colony stimulating factor 2) | protein interactions | 1437 | 18 | 9 | 19454 | 5460 |
ILF2,CSF2,SDC2,HNRNPA0,HNRNPA1,S100A6,SYNCRIP,PABPC1,HNRNPA2B1 |
| 3.998e-02 | -3.22 | SHISA2 (shisa family member 2) | protein interactions | 387914 | 18 | 9 | 19454 | 5460 |
RHOB,RAB4A,KRAS,EPHX1,ATXN1L,RAB5C,LNX2,RAP1B,GJA1 |
| 3.998e-02 | -3.22 | PPP1R3B (protein phosphatase 1 regulatory subunit 3B) | protein interactions | 79660 | 18 | 9 | 19454 | 5460 |
PYGB,PYGM,NUP153,GPRASP2,PPP1CB,PPP1CC,TOP3B,STBD1,GYS1 |
| 3.998e-02 | -3.22 | DDX60L (DExD/H-box 60 like) | protein interactions | 91351 | 18 | 9 | 19454 | 5460 |
RBM3,ZCCHC10,IFI16,MYC,ABCB9,PTGES3,CGAS,DCAF4,ATP5F1B |
| 3.998e-02 | -3.22 | GDAP2 (ganglioside induced differentiation associated protein 2) | protein interactions | 54834 | 18 | 9 | 19454 | 5460 |
ZBED1,RPA2,FBXW11,POLE3,AHSA1,VIRMA,RPA3,REP15,CFTR |
| 3.998e-02 | -3.22 | PMF1-BGLAP (PMF1-BGLAP readthrough) | protein interactions | 100527963 | 18 | 9 | 19454 | 5460 |
GNPAT,DSN1,CBX5,ZMPSTE24,NDUFAF6,CBX3,KRAS,FBXW7,CMTM6 |
| 3.998e-02 | -3.22 | TSPAN1 (tetraspanin 1) | protein interactions | 10103 | 18 | 9 | 19454 | 5460 |
RETREG3,CSGALNACT2,SEC62,MTCH2,NFKBIB,EXTL2,FAM241B,TLCD2,CD9 |
| 3.998e-02 | -3.22 | CCNQ (cyclin Q) | protein interactions | 92002 | 18 | 9 | 19454 | 5460 |
FBXO31,EIF4E2,KRBOX4,PTPN5,CCNA2,TAX1BP1,CDK9,GPR37,UBB |
| 3.998e-02 | -3.22 | LHCGR (luteinizing hormone/choriogonadotropin receptor) | protein interactions | 3973 | 18 | 9 | 19454 | 5460 |
PITPNA,FURIN,GNAI2,MAP2K1,NHERF1,TSHR,MPG,LHB,CHST9 |
| 3.998e-02 | -3.22 | MAP1LC3B2 (microtubule associated protein 1 light chain 3 beta 2) | protein interactions | 643246 | 18 | 9 | 19454 | 5460 |
RUSF1,SQSTM1,SNX33,HDAC6,ATG3,SAMM50,CAV1,RETREG1,TSPAN3 |
| 3.998e-02 | -3.22 | PPCDC (phosphopantothenoylcysteine decarboxylase) | protein interactions | 60490 | 18 | 9 | 19454 | 5460 |
UBE2I,SREK1IP1,NTAQ1,DDIT4L,RIT1,PPIG,PLEKHF2,KRAS,PSMA1 |
| 3.998e-02 | -3.22 | C1orf116 (chromosome 1 open reading frame 116) | protein interactions | 79098 | 18 | 9 | 19454 | 5460 |
RBBP7,PRNP,SMAD2,HEXIM1,HOMER1,CCR1,SMAD3,HRAS,HOMER3 |
| 3.998e-02 | -3.22 | PAPPA (pappalysin 1) | protein interactions | 5069 | 18 | 9 | 19454 | 5460 |
SMAD9,SMAD2,IGFBP4,VIRMA,PLG,H2AX,CREBBP,ANP32A,SMAD3 |
| 3.998e-02 | -3.22 | PROM1 (prominin 1) | protein interactions | 8842 | 18 | 9 | 19454 | 5460 |
SRC,SIGLECL1,KRAS,ACTB,HDAC6,TSG101,SYNJ2BP,TOMM22,PIK3R1 |
| 3.998e-02 | -3.22 | MVB12B (multivesicular body subunit 12B) | protein interactions | 89853 | 18 | 9 | 19454 | 5460 |
CERS2,SPPL3,KRAS,VPS28,PDE2A,TOP3B,METTL15,FEM1B,TSG101 |
| 3.998e-02 | -3.22 | BEX4 (brain expressed X-linked 4) | protein interactions | 56271 | 18 | 9 | 19454 | 5460 |
PKNOX1,MPPED2,GNB1L,GFM2,CDKN2C,LYPLA1,FAAP100,HSPB2,HSD17B8 |
| 3.998e-02 | -3.22 | RILPL1 (Rab interacting lysosomal protein like 1) | protein interactions | 353116 | 18 | 9 | 19454 | 5460 |
SEC22A,APPBP2,NTAQ1,TRAF3IP3,RAB11A,MOV10,APEX1,PIP4P1,HNRNPL |
| 3.998e-02 | -3.22 | regulation of neurotransmitter secretion | biological process | GO:0046928 | 82 | 32 | 18204 | 5365 |
RAB3A,SYT4,SV2B,STX1A,RAB5A,CPLX3,CPLX1,WNT7A,P2RY1,P2RY4,SNCG,RAP1B,MEF2C,SLC4A8,BGLAP,RAP1A,ASIC1,CPLX2,PRKCB,SLC38A2,CACNB4,VPS18,SNAPIN,PREPL,PPFIA2,HCRT,NLGN1,RIMS3,SYP,RIMS4,STXBP1,CASK |
| 3.998e-02 | -3.22 | regulation of bone mineralization | biological process | GO:0030500 | 82 | 32 | 18204 | 5365 |
OSR2,FAM20C,RFLNA,SOX9,ACVR1,MIR208A,GJA1,SGMS2,MGP,CCL3,SRGN,ZMPSTE24,PTN,SLC8A1,GREM1,ADRB2,ISG15,FGF23,SMAD3,CYP27B1,BMPR1A,ATRAID,WNT10B,BMPR1B,GPM6B,ANKH,SLC20A2,MEF2C,BGLAP,BMPR2,CCR1,VDR |
| 4.001e-02 | -3.22 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 34 | 15 | 16828 | 4835 |
SF3B1,RUNX1,IDH1,KRAS,HRAS,UBE2G2,EZH2,MYD88,JAK2,PTPN11,ETV6,IDH2,KIT,SRSF2,TP53 |
| 4.007e-02 | -3.22 | sinonasal_and_nasal_cavity | COSMIC cancer mutations | sinonasal_and_nasal_cavity | 84 | 32 | 16828 | 4835 |
CTNNB1,AKT1,IDH2,EP300,PIK3CA,NAB2,DICER1,DBH,EZH2,HNRNPA1,HRAS,HNMT,TUBA1A,PIK3R1,PCDH17,STK11,MAP2K1,SF3B1,EWSR1,KIT,TP53,JAK2,FBXW7,LRRTM3,TERT,PTEN,PID1,KRAS,EIF3K,IDH1,TSG101,CYP11B1 |
| 4.011e-02 | -3.22 | Termination of translesion DNA synthesis | REACTOME pathways | R-HSA-5656169 | 34 | 16 | 10285 | 3229 |
RPS27A,POLD2,UBA52,RFC4,RPA2,UBB,POLE3,PCNA,ISG15,POLE4,PCLAF,RFC3,RPA3,RFC2,RFC5,POLD4 |
| 4.011e-02 | -3.22 | Negative regulation of FGFR2 signaling | REACTOME pathways | R-HSA-5654727 | 34 | 16 | 10285 | 3229 |
CBL,PPP2R1A,UBB,RPS27A,FGF22,UBA52,PTPN11,FGF23,PPP2CB,FGF17,FGF10,FGF1,FGF7,SRC,FGF16,FGF3 |
| 4.014e-02 | -3.22 | Integrated Pancreatic Cancer Pathway | WikiPathways | WP2377 | 197 | 83 | 5310 | 1910 |
SP1,EIF2AK2,GTF2A2,PIAS1,FAS,CAPN1,PML,GADD45A,PTEN,FGF1,JUN,BAD,CREBBP,HSP90AB1,CDKN1A,AR,PLN,DAG1,RAF1,MAPK4,SMAD4,STAT5A,FKBP1B,CST3,CCND1,FASLG,ABCB1,RB1CC1,MDM2,JUNB,ACHE,VEGFA,GSK3A,TRAF2,BAX,KRAS,PTTG1,EGR1,MNAT1,AKT1,NME1,IGF1,DFFA,BRCA1,RHEB,MAP2K1,PIK3CA,RAP1A,RRM1,EP300,ARF1,CTNNB1,TNF,ESR2,IGFBP3,CDKN1B,PRKCA,NFKB1,NFKBIA,FKBP1A,FTL,E2F4,SERPINB10,HPGDS,SRC,NCK1,MYC,SMAD2,TYMS,STAT1,CAB39,IL3,CASP12,CDK4,CAMP,FGFR1,TOP1,STK11,EZH2,TP53,PCNA,CCNA2,CREB1 |
| 4.020e-02 | -3.21 | dendritic cell differentiation | biological process | GO:0097028 | 36 | 16 | 18204 | 5365 |
NOTCH2,IL4,LILRB1,RBPJ,TRAF6,ITGB8,LTBR,CCL19,IRF8,CCR7,TGFBR2,IRF4,AZI2,CSF2,BATF,PSEN1 |
| 4.020e-02 | -3.21 | lymphocyte apoptotic process | biological process | GO:0070227 | 36 | 16 | 18204 | 5365 |
PDCD1,BAK1,GPAM,BAX,TRAF3IP2,LIPA,KDELR1,FASLG,CRKL,LMBR1L,DFFA,IL2RA,TP53,FAS,BCL10,AKT1 |
| 4.027e-02 | -3.21 | SIRT3 (sirtuin 3) | protein interactions | 23410 | 89 | 33 | 19454 | 5460 |
MRPS18B,HSD17B10,UGDH,HSPD1,MRPS18C,HSPA5,PDHB,HSCB,H3C1,ATP5F1D,RUVBL1,CNP,ELP3,HSDL2,SSBP3,PDHA1,IDH2,NDUFS6,HSP90B1,YBEY,MCL1,SDHB,UQCRH,MALSU1,MDM2,SRC,ESR2,ATP5F1B,SNX3,ATP5F1A,MTG2,PYCR1,LSM14B |
| 4.027e-02 | -3.21 | mucopolysaccharide metabolic process | biological process | GO:1903510 | 85 | 33 | 18204 | 5365 |
CSGALNACT2,IL1B,ANGPT1,EXT1,CHST2,CHST1,BPNT2,HAS3,CHST7,UGDH,ST3GAL2,CHST11,ST3GAL4,HS2ST1,UST,CHPF2,NDST3,CHST13,B4GALT4,EDNRA,CHPF,CHST9,ABCC5,ST3GAL1,B4GAT1,CSGALNACT1,HEXB,TNFAIP6,B3GNT2,HEXA,NDST1,HYAL2,GLCE |
| 4.027e-02 | -3.21 | TCTN1 (tectonic family member 1) | protein interactions | 79600 | 149 | 52 | 19454 | 5460 |
RPN1,SELENOF,ERLIN2,GFPT1,CCDC134,EMC8,LCN9,ERLEC1,RIGI,PRDX4,SIAE,PRPS1,FKBP2,SEC11A,PDIA6,ERP29,ART5,ERO1A,SLC39A7,AGPAT1,CALR,PDIA3,B9D1,PPIB,PCSK9,TMED9,OS9,LMAN1,DNM2,CHID1,MAP2K1,HSP90B1,P3H1,FKBP10,TMEM231,CNPY3,GPIHBP1,SRSF2,EMC1,B9D2,HSPA5,APMAP,DNAJC3,CST11,DNAJC10,SPCS3,SDF2L1,CALU,SERPINH1,NPTX1,SEC63,GANAB |
| 4.041e-02 | -3.21 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | 75 | 29 | 16828 | 4835 |
MAP2K1,GNAQ,SF3B1,PGAM1,HRAS,GNPAT,PIK3CA,DICER1,VWF,SMARCB1,DDT,CDH11,SRSF2,CTNNB1,RB1,GNA11,AKT1,PTPN11,KRAS,SQSTM1,NCK1,IDH1,TERT,ABCC5,PTEN,TP53,DAPK3,KIT,FBXW7 |
| 4.047e-02 | -3.21 | ATF-2 transcription factor network | Pathway Interaction DB | atf2_pathway | 55 | 26 | 2226 | 782 |
JUNB,TGFB2,CXCL8,FOS,CCNA2,RUVBL2,DUSP1,SOCS3,ATF3,PRKCA,CREB1,DUSP10,EP300,CBFB,GADD45A,IL6,DDIT3,ACHE,IL23A,IFNG,MACROH2A1,BRCA1,JUN,CUL3,CDK4,CCND1 |
| 4.058e-02 | -3.20 | positive regulation of T cell differentiation | biological process | GO:0045582 | 121 | 45 | 18204 | 5365 |
DUSP10,LILRB4,RHOH,KLHL25,SMARCE1,MIR21,IL2,TGFBR2,CCL19,BTN2A2,CD46,IL4,NLRP3,FOXP3,BCL6,ZBTB16,SOCS5,CD83,IL18,PNP,RUNX1,NKAP,ACTL6A,SASH3,XBP1,SMARCD3,SYK,IL2RG,BAD,CD86,IL7,RAG1,CD80,CBFB,TESPA1,IL23A,IFNG,SMARCB1,WNT10B,IL12B,VSIR,ACTB,EP300,IL2RA,ACTL6B |
| 4.058e-02 | -3.20 | DST (dystonin) | protein interactions | 667 | 230 | 77 | 19454 | 5460 |
DIRAS3,LMAN1,STX6,STK3,CAV1,CDC5L,COPS7B,RHOH,GJA1,ADD1,RAC2,RAB35,TNIK,SMAD9,MED4,YWHAB,STYK1,PTGER4,AGR2,YWHAH,YWHAG,CTNNB1,EXOC1,ATG9A,LAMP2,UBXN6,RPL6,FLOT1,KRAS,ATP1A2,G3BP1,CASTOR2,NTRK2,RND3,NUPR1,RAB4A,DISC1,CAPZA2,SNAPIN,TULP3,TBK1,TOP3B,CSTF3,ESR2,VIRMA,ACTB,GSK3A,PRMT5,PHF21A,OPTN,EPHA2,NCKIPSD,UBE2H,VMP1,MAPRE1,LAMTOR1,BRCA1,YWHAZ,RSPH1,MYC,SFN,RAB11A,TOMM20,STX7,KDM1A,RAB5A,RAB9A,RPA3,BAP1,RHOU,SIRT7,RPA2,PAK2,PPP1CB,RND2,TOMM22,BET1 |
| 4.061e-02 | -3.20 | skin-lower_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-lower_leg-other-atypical_Spitzoid_tumour | 23 | 11 | 16828 | 4835 |
LMNA,PPFIBP1,TP53,GNA11,KIT,HRAS,TPM3,GOLGA5,LSM14A,BAP1,GNAQ |
| 4.061e-02 | -3.20 | skin-arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-arm-other-atypical_Spitzoid_tumour | 23 | 11 | 16828 | 4835 |
TPM3,LMNA,PPFIBP1,TP53,KIT,GNA11,GOLGA5,LSM14A,GNAQ,BAP1,HRAS |
| 4.061e-02 | -3.20 | skin-face-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-face-other-atypical_Spitzoid_tumour | 23 | 11 | 16828 | 4835 |
LSM14A,GNAQ,BAP1,GOLGA5,HRAS,TPM3,TP53,KIT,GNA11,LMNA,PPFIBP1 |
| 4.061e-02 | -3.20 | basal_cell_carcinoma | COSMIC cancer mutations | basal_cell_carcinoma | 23 | 11 | 16828 | 4835 |
AKT1,NOTCH2,KIT,HRAS,KRAS,CTNNB1,TP53,SUFU,DICER1,TERT,PIK3CA |
| 4.061e-02 | -3.20 | skin-face-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-face-malignant_melanoma-lentigo_maligna | 23 | 11 | 16828 | 4835 |
PIK3CA,STK11,GNAQ,FGFR1,JAK2,AKT1,KIT,MET,HRAS,CTNNB1,KRAS |
| 4.061e-02 | -3.20 | skin-scalp-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-scalp-benign_melanocytic_nevus-Spitz | 23 | 11 | 16828 | 4835 |
LSM14A,GNAQ,BAP1,GOLGA5,HRAS,TPM3,TP53,KIT,GNA11,LMNA,PPFIBP1 |
| 4.061e-02 | -3.20 | atypical_Spitzoid_tumour | COSMIC cancer mutations | atypical_Spitzoid_tumour | 23 | 11 | 16828 | 4835 |
PPFIBP1,LMNA,HRAS,KIT,GNA11,TP53,TPM3,GOLGA5,BAP1,GNAQ,LSM14A |
| 4.061e-02 | -3.20 | skin-upper_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_leg-other-atypical_Spitzoid_tumour | 23 | 11 | 16828 | 4835 |
GOLGA5,LSM14A,BAP1,GNAQ,HRAS,TPM3,LMNA,PPFIBP1,TP53,GNA11,KIT |
| 4.066e-02 | -3.20 | C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone | KEGG pathways | M00108 | 3 | 3 | 7161 | 2463 |
CYP11B2,CYP21A2,CYP11B1 |
| 4.066e-02 | -3.20 | C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone | KEGG pathways | hsa_M00108 | 3 | 3 | 7161 | 2463 |
CYP11B2,CYP11B1,CYP21A2 |
| 4.069e-02 | -3.20 | cellular response to BMP stimulus | biological process | GO:0071773 | 91 | 35 | 18204 | 5365 |
BMPR2,PDCD4,SOST,MSX1,SFRP1,RGMA,DDX5,RGMB,NOTCH2,TWSG1,BMPR1B,SMAD9,SMAD1,TMEM100,BMPR1A,EGR1,SOSTDC1,DLX1,FKBP8,SMAD5,USP15,PPARG,MSX2,NOG,MIR30B,MIR21,SMAD4,CHRDL1,EXT1,SPINT2,VSTM2A,SMURF1,HFE,SOX9,ACVR1 |
| 4.069e-02 | -3.20 | response to BMP | biological process | GO:0071772 | 91 | 35 | 18204 | 5365 |
DLX1,FKBP8,EGR1,BMPR1A,SOSTDC1,TMEM100,BMPR1B,TWSG1,RGMB,NOTCH2,SMAD1,SMAD9,RGMA,DDX5,SOST,MSX1,SFRP1,PDCD4,BMPR2,SOX9,ACVR1,HFE,VSTM2A,SMURF1,EXT1,SPINT2,CHRDL1,SMAD4,MIR30B,MIR21,MSX2,NOG,PPARG,USP15,SMAD5 |
| 4.069e-02 | -3.20 | fatty acid catabolic process | biological process | GO:0009062 | 91 | 35 | 18204 | 5365 |
PHYH,CRAT,ETFB,HSD17B10,ILVBL,HADHA,ADIPOQ,MCAT,ABHD2,CPT1B,AUH,ACADS,CPT2,SLC25A17,DECR2,ECHDC1,ACAA2,NUDT19,PLA2G15,PEX13,SESN2,AMACR,CYP4F12,EHHADH,PCK2,ACOT8,HADH,LEP,NUDT7,ACAT1,ETFA,ADTRP,PCCB,ACOX1,AIG1 |
| 4.069e-02 | -3.20 | regulation of fibroblast proliferation | biological process | GO:0048145 | 91 | 35 | 18204 | 5365 |
B4GALT7,FTH1,NUPR1,IL13,SOD2,CD248,SFRP1,GSTP1,LTA,TRIM32,FGF10,CTNNB1,MYC,FOSL2,TP53INP1,WNT2,BAX,TP53,CDKN1A,ING5,PML,CAV1,IGF1,MED31,CDK4,CDK6,CCNA2,CDC73,HRAS,CCNB1,DHX9,ZMPSTE24,MIF,MIR17,S100A6 |
| 4.069e-02 | -3.20 | primary alcohol metabolic process | biological process | GO:0034308 | 91 | 35 | 18204 | 5365 |
SULT1B1,ADH1B,HSD17B6,ALDH1A3,RETSAT,AKR1B1,DHRS4,DHRS3,CYP2C8,CYP1A1,GDE1,SULT1A3,CYP2D6,CYP3A5,GDPD3,CYP1B1,TKTL1,RDH11,ADH1A,RDH10,RDH12,CYP2C18,THTPA,AKR1A1,CYP11B1,AKR1C1,IGF1,CYP11B2,AKR1C2,AKR7A2,SDR16C5,LRAT,CBR4,PNPLA4,DHRS7 |
| 4.069e-02 | -3.20 | response to heat | biological process | GO:0009408 | 91 | 35 | 18204 | 5365 |
CRYAB,HSPB1,SLU7,EIF2B2,HSPB2,EIF2B3,SUMO1,HSP90AB1,TP53INP1,EIF2S1,TCIM,CDKN1A,FGF1,IL1A,CLPB,DNAJB4,RBBP7,HSPB6,IGF1,CXCL10,EIF2B5,SOD1,HSP90AA1,HDAC6,SLC52A3,HIKESHI,MICB,HSPA8,HSBP1,AKT1,BAG3,STUB1,SCN2B,GCLC,HTRA2 |
| 4.069e-02 | -3.20 | cellular response to glucose stimulus | biological process | GO:0071333 | 91 | 35 | 18204 | 5365 |
UCP2,SIN3A,PIK3CA,KCNB1,PAX6,RAF1,SMAD3,ICAM1,FKBP1B,TWNK,IGF1R,MIRLET7G,TRA2B,CMA1,MIR16-1,CLTRN,MIR15A,GPX1,KCNJ11,XBP1,PCK2,GCLC,PPP3CA,MIR320A,SMAD2,RAB11B,OPRK1,CYP7A1,SLC29A1,CCDC186,AGER,SELENOT,SMAD4,NPTX1,MIR146A |
| 4.075e-02 | -3.20 | Bcl-2 family protein complex | cellular component | GO:0097136 | 10 | 6 | 19108 | 5553 |
BCL2L1,BAK1,BAX,BAD,PMAIP1,MCL1 |
| 4.075e-02 | -3.20 | N-terminal protein acetyltransferase complex | cellular component | GO:0031414 | 10 | 6 | 19108 | 5553 |
NAA15,NAA11,NAA35,NAA16,NAA30,NAA50 |
| 4.075e-02 | -3.20 | Golgi trans cisterna | cellular component | GO:0000138 | 10 | 6 | 19108 | 5553 |
GCC1,ST3GAL1,TMEM59,SGMS1,B4GALT1,ST6GAL1 |
| 4.075e-02 | -3.20 | FNIP-folliculin RagC/D GAP | cellular component | GO:1990877 | 10 | 6 | 19108 | 5553 |
FLCN,LAMTOR2,RRAGA,LAMTOR1,SLC38A9,LAMTOR3 |
| 4.082e-02 | -3.20 | fatty acid biosynthetic process | biological process | GO:0006633 | 115 | 43 | 18204 | 5365 |
ELOVL7,HACD1,HPGDS,ELOVL6,CYP2C9,CBR4,PTGDS,ABHD2,ACACA,ELOVL1,PRKAG1,PLP1,PNPLA8,BRCA1,HACD3,TECR,CYP2D6,XBP1,GPX4,GSTM4,CYP2C8,CYP1A1,MECR,ELOVL4,HACD2,FADS2,MCAT,ELOVL3,DEGS1,FA2H,PTGES,DECR2,LIAS,PRKAB1,GSTP1,ACSS2,GSTM2,SCD5,NDUFAB1,MIF,PTGES3,HSD17B8,HACD4 |
| 4.083e-02 | -3.20 | cellular response to hexose stimulus | biological process | GO:0071331 | 94 | 36 | 18204 | 5365 |
PAX6,SIN3A,PIK3CA,KCNB1,UCP2,SMAD3,RAF1,ICAM1,TWNK,FKBP1B,MIR16-1,CMA1,MIRLET7G,TRA2B,IGF1R,CLTRN,GPX1,MIR15A,PCK2,GCLC,XBP1,KCNJ11,MIR320A,PPP3CA,RAB11B,SMAD2,SLC29A1,CYP7A1,OPRK1,CCDC186,PPARA,AGER,MIR146A,SMAD4,NPTX1,SELENOT |
| 4.084e-02 | -3.20 | ATXN1 (ataxin 1) | protein interactions | 6310 | 469 | 149 | 19454 | 5460 |
BAALC,FAM168A,BAG2,ZYX,GCA,DMPK,KRTAP12-4,PAX6,ZNF609,LASP1,TRIM37,GNL1,PPP2R1A,FUT9,SOX2,TRAF2,MSX2,HPCAL1,VSTM2L,ANP32A,KLHL12,PCBP4,ZHX1,SGMS1,PTGDS,DUSP6,MYEF2,FUBP3,HNRNPL,SUMO2,YWHAG,YWHAH,ZNF207,TBC1D5,CRIP1,CDIP1,CST3,YWHAB,HSPB1,LHX2,HSPA8,DCTN3,CHRNA7,COIL,SKP1,EIF1B,SOX3,AKIP1,MTMR6,KLF3,SYBU,ZHX3,ATXN1L,ELK3,IL34,GGPS1,BTG3,PRRC2A,TCAP,TAB1,LDB1,MLF2,NFYA,CREBBP,HNF1B,PSMA4,SFN,OAZ1,DNAJB6,CIRBP,SPCS3,POMP,ATP1A3,YWHAZ,LPAR2,PQBP1,BHLHE40,LPCAT3,PRDX4,H3C1,TOLLIP,EGR2,SLC51A,IPO8,OTX2,PSMC3,CAMK1,GPD2,SIX5,PSMB1,CDK6,GATAD1,PTPN1,EIF4E2,TCTA,CITED1,ILVBL,MSMO1,KCTD15,FNDC9,TPM3,GAPDH,IRF4,DHRS11,EID1,MED27,SQSTM1,TMX2,PML,PIAS1,TOMM20,HSPA5,KDM1A,HDAC3,LITAF,SLC25A51,KLF12,ZSCAN1,DUSP18,RBFOX2,SUMO1,PAX9,ACACA,TOX4,CDK1,PICALM,HEY2,CSNK2B,UBE2I,STUB1,PELP1,GCFC2,SCAMP2,VIRMA,BUB3,PPAT,CFL1,AR,UTS2,HMOX2,MLF1,AKT1,CDC16,TRIM32,CIAO1,FAM193B,PIM2,CHORDC1,UBE2E3 |
| 4.091e-02 | -3.20 | mononuclear cell migration | biological process | GO:0071674 | 112 | 42 | 18204 | 5365 |
CCR5,H2BC1,CCL23,SLC12A2,CXCR1,HMGB1,MSMP,EXT1,RPL13A,CH25H,CKLF,CCL3,F11R,CCL21,PLG,PIK3CG,GPR15,EPS8,CCL20,CRKL,MSN,CCR6,CXCL13,JAML,FOLR2,CCR7,CCR2,CCL19,SFTPD,CXCR4,ICAM1,B4GALT1,XCL1,CXCL10,LGALS3,CCL2,CCL5,CDC42,CXCL11,SELENOK,CCR1,IL6 |
| 4.091e-02 | -3.20 | regulation of cytoplasmic pattern recognition receptor signaling pathway | biological process | GO:0039531 | 112 | 42 | 18204 | 5365 |
ATAT1,CGAS,NEK7,PYDC2,LYPLAL1,BIRC2,TNFAIP3,TAX1BP1,RSAD2,CD36,MAVS,TAB1,TRIM15,MIR708,TIRAP,TASL,CPTP,CAV1,TRIM11,CSNK1A1,PELI1,BANF1,SEC14L1,FLOT1,TLR4,HCFC2,USP15,SLC15A2,TLR6,AKT1,EIF2AK2,NOP53,SRC,TRIM3,MYD88,HSPA8,TLR9,HMGB1,UFD1,PTPN22,RTN4,ABHD17A |
| 4.091e-02 | -3.20 | NF-kB is activated and signals survival | REACTOME pathways | R-HSA-209560 | 14 | 8 | 10285 | 3229 |
IKBKB,NFKB1,TRAF6,UBA52,RPS27A,UBB,SQSTM1,NFKBIA |
| 4.091e-02 | -3.20 | Removal of the Flap Intermediate | REACTOME pathways | R-HSA-69166 | 14 | 8 | 10285 | 3229 |
POLD2,RPA2,PRIM2,POLA2,PCNA,FEN1,RPA3,POLD4 |
| 4.091e-02 | -3.20 | Trafficking and processing of endosomal TLR | REACTOME pathways | R-HSA-1679131 | 14 | 8 | 10285 | 3229 |
TLR3,CTSK,CTSB,TLR8,TLR9,HSP90B1,CNPY3,TLR7 |
| 4.092e-02 | -3.20 | ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif 1) | protein interactions | 9510 | 86 | 32 | 19454 | 5460 |
DKK3,VEGFA,LMBR1L,VIRMA,NPC2,DYRK1A,CELA3B,BMP1,SNX18,DDRGK1,CUL3,ZMYND19,ARMC8,NTRK3,YPEL5,IGF1R,RMND5B,MKLN1,FBXO11,DLG1,MAEA,GID8,BAP1,GID4,LIN7C,HSPA5,RANBP10,CFTR,CCL3,CER1,NOTCH2,FURIN |
| 4.092e-02 | -3.20 | PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1) | protein interactions | 5092 | 86 | 32 | 19454 | 5460 |
TRIM5,PICK1,RPS24,DVL2,ZBTB25,ZNF451,GTF3C3,PSMA1,FXR2,SAP30,ZNF263,RAF1,SUPT5H,ZMYM6,SDCBP,ADSS2,WWP1,NUDT18,UBB,DCUN1D1,PRNP,COPS5,NTAQ1,GORASP2,PCBD1,HNF1B,MYC,DYRK1B,NFKB1,CUL3,ZNF688,NIF3L1 |
| 4.097e-02 | -3.19 | positive regulation of proteasomal protein catabolic process | biological process | GO:1901800 | 109 | 41 | 18204 | 5365 |
RCHY1,ZER1,CSNK1E,FBXO22,GSK3A,FZR1,CDC20,SUMO1,NUPR1,USP5,PSMC4,PSMD10,DET1,DDRGK1,NFE2L2,MDM2,CAV1,PSMC5,ZFAND2A,FBXW7,GABARAP,SOCS4,PSMC3,PIAS1,TRIB1,DNAJB2,CSNK1A1,PSEN1,SGTA,GCLC,CLU,PSMC1,USP13,HECTD1,COP1,STUB1,SOCS5,AKT1,BAG2,NOP53,SUMO2 |
| 4.098e-02 | -3.19 | maturation of SSU-rRNA | biological process | GO:0030490 | 53 | 22 | 18204 | 5365 |
GTF2H5,NOP9,NOB1,RCL1,RPS16,TSR2,NGDN,RPS14,TSR3,LSM6,RIOK2,PWP2,IMP3,RPS28,UTP25,MPHOSPH10,WDR3,NOL7,UTP6,IMP4,SRFBP1,UTP23 |
| 4.098e-02 | -3.19 | negative regulation of myeloid leukocyte differentiation | biological process | GO:0002762 | 53 | 22 | 18204 | 5365 |
LILRB1,C1QC,IL4,TCTA,CCL3,PIK3R1,LILRB4,TLR4,INHA,GPR137,CARTPT,CDK6,TRIB1,FBXW7,TLR3,ADIPOQ,UBASH3B,SFRP1,TOB2,TNFAIP6,CTNNB1,MYC |
| 4.101e-02 | -3.19 | glycolipid metabolic process | biological process | GO:0006664 | 106 | 40 | 18204 | 5365 |
PIGC,GALC,ST6GALNAC3,GPAA1,B4GALT4,B3GALT2,BAX,HEXA,FUT9,PIGA,PIGW,UGCG,ST3GAL1,FA2H,PGAP4,HEXB,PGAP2,PGAP3,NEU1,GAL3ST1,ST3GAL5,B4GALT3,SLC30A5,LARGE1,FUT1,ST8SIA5,CERK,PIGK,KIT,ST3GAL4,B3GALT1,GAL3ST4,ST8SIA4,ITGB8,PIGY,DPM2,B3GALNT1,ST3GAL2,B3GALT4,B4GALT6 |
| 4.101e-02 | -3.19 | regulation of biomineral tissue development | biological process | GO:0070167 | 103 | 39 | 18204 | 5365 |
OSR2,FAM20C,RFLNA,SOX9,ACVR1,CCL3,SRGN,ZMPSTE24,MIR208A,GJA1,SGMS2,CFTR,MGP,GREM1,ADRB2,AMELX,MMP20,ATF4,PTN,SLC8A1,ISG15,HEY2,ATRAID,WNT10B,ROCK2,FGF23,SMAD3,BMPR1A,CYP27B1,GPM6B,BMPR1B,ANKH,SLC20A2,MEF2C,BGLAP,VDR,CCR1,BMPR2,ROCK1 |
| 4.106e-02 | -3.19 | MVP (major vault protein) | protein interactions | 9961 | 162 | 56 | 19454 | 5460 |
STN1,PSMD14,BRCA1,COP1,PTPN11,MYC,CDC16,BAG3,H2BC9,NTAQ1,TENT5C,KCTD9,CMTR1,PTEN,TRIM27,STX17,GIT2,CFTR,FBXW7,FXR2,NF2,SIRT7,RAB5A,HSPA8,TRAF6,CBL,EMC4,WWP2,MDFI,CSNK2A1,HP,CGAS,EIF2B5,CDC5L,HSP90AB1,UBTD2,TNIK,PTPN1,MAP1LC3A,DISC1,TFCP2,EZH2,HSPA13,VAC14,TP53,FBP1,TRAF2,TRIM37,KPNA2,TOLLIP,TNF,KRAS,SERTAD1,UTP25,PLSCR1,DHX9 |
| 4.124e-02 | -3.19 | CPEB4 (cytoplasmic polyadenylation element binding protein 4) | protein interactions | 80315 | 146 | 51 | 19454 | 5460 |
NUP42,CNOT7,G3BP1,CNOT6L,PABPC1,LSM14A,GARRE1,ZC3H7A,BSCL2,GLE1,GPBP1L1,TNRC6C,YTHDF2,RAF1,TOP3B,NDST1,FAM98A,EGLN3,FUBP3,AIFM1,SYNCRIP,TDRD7,DDX1,SAV1,MOV10,CNOT2,EDC3,CNOT8,STAU1,YTHDF1,FXR2,G3BP2,HSPA5,MCRIP2,AKAP1,SMG5,LSM12,LARP4B,AGO1,ACTB,VIRMA,PRRC2A,SMAP2,RTRAF,DCAF4,RC3H2,IGF2BP1,AP2A1,PAIP2,CEP85,FBXO7 |
| 4.132e-02 | -3.19 | IL-3 Signaling Pathway | WikiPathways | WP286 | 49 | 24 | 5310 | 1910 |
IL3,STAT5A,PIK3R1,SHC1,CRKL,FOS,YWHAB,AKT1,BCL2L1,MAP2K1,CCR3,CXCL8,JAK1,PTPN11,SYK,CBL,PIK3R2,JAK2,SRC,RAF1,CD86,HRAS,BAD,JUN |
| 4.133e-02 | -3.19 | Citrate cycle (TCA cycle, Krebs cycle) | KEGG pathways | M00009 | 22 | 12 | 7161 | 2463 |
IDH1,OGDHL,SDHB,IDH3A,DLST,IDH3B,SDHC,SUCLG2,ACO1,IDH2,MDH1,ACO2 |
| 4.133e-02 | -3.19 | Citrate cycle (TCA cycle, Krebs cycle) | KEGG pathways | hsa_M00009 | 22 | 12 | 7161 | 2463 |
SUCLG2,IDH2,ACO1,IDH1,IDH3B,DLST,SDHC,MDH1,SDHB,IDH3A,ACO2,OGDHL |
| 4.151e-02 | -3.18 | human chr17q23.3 | chromosome location | human chr17q23.3 | 36 | 13 | 26134 | 5823 |
LIMD2,CSH1,CYB561,TACO1,MAP3K3,CD79B,GH1,FTSJ3,DDX5,PSMC5,DDX42,ICAM2,CCDC47 |
| 4.153e-02 | -3.18 | Arhgap1 (Rho GTPase activating protein 1) | protein interactions | 228359 | 32 | 14 | 19454 | 5460 |
CDK9,HMGB1,PRDX2,WDR82,TACO1,PSPC1,CA2,LMNA,DDX42,ZNF207,PPIL4,CDC42,PYCR2,STOML2 |
| 4.153e-02 | -3.18 | ASB10 (ankyrin repeat and SOCS box containing 10) | protein interactions | 136371 | 32 | 14 | 19454 | 5460 |
POLD2,STUB1,SLC25A5,RPS10,KDM1A,MRPL23,ELOC,TUFM,PSMA4,SLC25A1,ARFGAP1,HSPB1,SLC25A3,RNF7 |
| 4.153e-02 | -3.18 | S1PR2 (sphingosine-1-phosphate receptor 2) | protein interactions | 9294 | 32 | 14 | 19454 | 5460 |
TSPAN15,ACP2,SRC,ARL6IP5,ATP5F1B,SPPL3,LPAR1,TNFSF18,HPCAL1,TNFAIP3,GNAQ,CSNK1G3,REEP6,FKBP14 |
| 4.153e-02 | -3.18 | CCDC174 (coiled-coil domain containing 174) | protein interactions | 51244 | 32 | 14 | 19454 | 5460 |
EIF4A3,ADIPOR2,BPIFA2,SAV1,MYC,STK4,XPO1,GSK3A,PSMD14,KRAS,RIGI,STK3,CERK,COIL |
| 4.153e-02 | -3.18 | OTUD6A (OTU deubiquitinase 6A) | protein interactions | 139562 | 32 | 14 | 19454 | 5460 |
CFTR,PPP2R1A,NUP62,MYC,EMX2,NLRP3,TOPBP1,TRIM5,PPP2CB,TOP2B,SSBP1,RBCK1,TRIM46,DYNLL1 |
| 4.153e-02 | -3.18 | RASA3 (RAS p21 protein activator 3) | protein interactions | 22821 | 32 | 14 | 19454 | 5460 |
RHOJ,HNRNPL,SPPL3,GNAI2,RAC2,GJA1,ARHGAP19,EID1,GNAI3,RAP1A,TOP3B,MYC,TBCEL,CDC42 |
| 4.153e-02 | -3.18 | GRIA4 (glutamate ionotropic receptor AMPA type subunit 4) | protein interactions | 2893 | 32 | 14 | 19454 | 5460 |
TUBA1B,GRIA1,SYNCRIP,DHX9,PICK1,HNRNPK,ACTB,CAMK2G,ESR2,CSK,ABHD5,SDCBP,TUBB4B,PRKCA |
| 4.153e-02 | -3.18 | QTRT2 (queuine tRNA-ribosyltransferase accessory subunit 2) | protein interactions | 79691 | 32 | 14 | 19454 | 5460 |
ADAT1,RPA2,GTPBP1,CUL3,ISG15,HSCB,EGLN3,THUMPD1,TFPT,RPA3,OPTN,ALB,COX8A,HSPA8 |
| 4.153e-02 | -3.18 | SLC14A1 (solute carrier family 14 member 1 (Kidd blood group)) | protein interactions | 6563 | 32 | 14 | 19454 | 5460 |
CFTR,VAMP2,STOM,FIS1,BTN2A2,BCL7B,CYBRD1,LGALS3,YES1,TMEM97,UBB,FLOT1,ATP6AP2,SRC |
| 4.153e-02 | -3.18 | CIAO3 (cytosolic iron-sulfur assembly component 3) | protein interactions | 64428 | 32 | 14 | 19454 | 5460 |
APEX1,NAA11,ZBTB39,FBXW7,STAT1,KRAS,NUBP2,INPPL1,DCAF16,CD2AP,CIAO1,TP53,GSTM3,MOV10 |
| 4.153e-02 | -3.18 | SERINC5 (serine incorporator 5) | protein interactions | 256987 | 32 | 14 | 19454 | 5460 |
RNF40,CUL3,TRAF6,WWP1,SYVN1,TRAF7,TRIM21,RLIM,MAVS,STUB1,VIRMA,RNF41,HUWE1,HNRNPL |
| 4.153e-02 | -3.18 | ATP11A (ATPase phospholipid transporting 11A) | protein interactions | 23250 | 32 | 14 | 19454 | 5460 |
CDC42,RND2,TMEM30A,RHOG,RHOB,PICK1,RAC2,RHOU,HRAS,VIRMA,KRAS,HNRNPL,RHOH,RHOJ |
| 4.153e-02 | -3.18 | Med22 (mediator complex subunit 22) | protein interactions | 20933 | 32 | 14 | 19454 | 5460 |
MVD,MED9,MED30,MED27,CDK8,MED23,MED10,MRPS25,MED29,MED4,MED31,MED13L,MED11,MED17 |
| 4.153e-02 | -3.18 | SLC25A23 (solute carrier family 25 member 23) | protein interactions | 79085 | 32 | 14 | 19454 | 5460 |
APLNR,PAEP,SLC22A6,APPBP2,HSPA8,TMEM108,AIFM1,CD79B,OSTM1,SYP,AQP3,PDCD1,MGARP,CUL3 |
| 4.153e-02 | -3.18 | PPP1R3C (protein phosphatase 1 regulatory subunit 3C) | protein interactions | 5507 | 32 | 14 | 19454 | 5460 |
AASDHPPT,MYO1B,GNG5,SGTA,PHKB,ARG2,GYS1,LXN,LACRT,MYO6,PPP1CB,PPP1CC,STBD1,TXNRD2 |
| 4.153e-02 | -3.18 | CCL4L2 (C-C motif chemokine ligand 4 like 2) | protein interactions | 9560 | 32 | 14 | 19454 | 5460 |
MFSD14B,TMEM179B,CLRN1,ERVFRD-1,SLC7A14,SLC7A1,REEP4,JAGN1,SSMEM1,VSIR,COMT,ELOVL4,MFSD5,RETREG3 |
| 4.156e-02 | -3.18 | THEM4 (thioesterase superfamily member 4) | protein interactions | 117145 | 83 | 31 | 19454 | 5460 |
GATD3,HDHD3,DBT,PARL,HNRNPL,TUFM,ACO2,AKT1,GRSF1,MTRF1,AUH,PMPCA,MRPS26,RHOG,TMEM70,HINT2,PDSS2,GFM1,HSPD1,FASTKD5,IMMP2L,HSCB,AURKAIP1,LBH,NDUFAB1,CMPK1,MRPL11,KLC2,MRPL49,MTRES1,PDHA1 |
| 4.156e-02 | -3.18 | SALL2 (spalt like transcription factor 2) | protein interactions | 6297 | 83 | 31 | 19454 | 5460 |
GPX1,LURAP1,CCNF,PHF21A,VRTN,WDR45,TEX19,ASB7,POU5F1,MYC,DSN1,CDC16,ATG7,ASF1A,KDM1A,RBBP7,PTGES3,ASB3,RCCD1,IRF3,S100B,BAP1,RPA3,RLIM,BAG2,EWSR1,RPA2,PRMT2,TSHR,ING1,SOX2 |
| 4.156e-02 | -3.18 | DNM3 (dynamin 3) | protein interactions | 26052 | 83 | 31 | 19454 | 5460 |
IL1R2,GBE1,RPE,MND1,HCST,FGFR1,HSPA13,HECTD1,SNX33,THBS3,EP300,EFNB1,SLC39A7,GPM6A,KRAS,MRPS18C,FXYD6,SNX5,TYROBP,DNM2,SCN2B,S100A6,AMIGO1,LYPD6,SNX2,SNX1,DYNLL1,DYRK1A,ZBTB2,VIRMA,HOMER1 |
| 4.156e-02 | -3.18 | KIF15 (kinesin family member 15) | protein interactions | 56992 | 83 | 31 | 19454 | 5460 |
PGK1,JAK1,INPPL1,PHYHIP,PTGES3,FANCG,KDM1A,DGCR8,CD2AP,ATG16L1,TRIM36,HSP90B1,MAP1LC3A,PPP2R5E,KRT8,PHF21A,ANAPC2,DEK,VIRMA,FBXO22,AR,MLF2,USP14,MYC,KXD1,MPC1,NDC80,COP1,USP15,KIAA1143,PPM1B |
| 4.156e-02 | -3.18 | MFSD5 (major facilitator superfamily domain containing 5) | protein interactions | 84975 | 83 | 31 | 19454 | 5460 |
TMEM237,SPPL3,SSMEM1,ADGRE2,TMEM179B,C2CD2L,PLN,UPK1A,CCR6,SCN3B,GPR17,CREB3,GRPR,LPAR1,TMEM203,BSCL2,TACR1,VIPR1,CD40,SLC39A9,CYB5B,CLRN1,TMEM14B,LMNA,YIPF3,GOSR2,TIMMDC1,SEC22B,TOP3B,ERRFI1,BLCAP |
| 4.168e-02 | -3.18 | FHL2 (four and a half LIM domains 2) | protein interactions | 2274 | 389 | 125 | 19454 | 5460 |
CPLX3,MEAF6,MITF,EGLN3,TRMT61A,SIN3A,SP2,RBM5,TRAF6,IFI16,PSMD3,CNOT2,CNOT8,CTNNB1,GAS8,ZBTB16,TRIM37,VXN,CCAR1,ATF3,FHL3,EZH2,ITGB5,ODAM,E2F4,ELF1,SAP30,FANCD2OS,TAX1BP1,LRIF1,MORC4,BTG3,DOK4,GNG12,CNOT6,SCNM1,GTF2F2,PHF21A,BRCA1,RBM27,SP1,DSN1,MYC,CREBBP,CUL3,BTF3,BRMS1,ATF1,EYA3,PHB2,SLU7,EP300,DCTN3,ZFP64,NACC2,LARP4B,NUFIP2,PRR5L,RASL12,AKIP1,VTI1B,BRMS1L,TXNRD3,MDM2,BARX2,SMAD3,IER3,GATAD1,TES,SMAD4,CCDC92,FOXP1,E4F1,ZNF200,CNOT7,TOLLIP,TRIM63,CNOT6L,CDC42SE1,PHF1,CAPZA1,ZBTB25,IDH1,CAPZA2,SIX5,BMPR2,SAP30L,MTCH2,SP4,ING1,EEF1A1,ZMYM4,GABPA,DUSP10,DYRK1A,CREB1,ING2,QSER1,EPCAM,ZNF655,ATOSB,PKNOX1,SMAD2,BMERB1,CDC73,IFI35,CSK,RUNX1,PPP1CC,AR,PDHB,CDC42EP4,BAP1,PML,PSEN2,HSPB2,RNF113A,JUP,HEXIM1,CIMIP1,DDIT4L,SAP30BP,CAPN1,CFTR,KLF12 |
| 4.172e-02 | -3.18 | OST4 (oligosaccharyltransferase complex subunit 4, non-catalytic) | protein interactions | 100128731 | 108 | 39 | 19454 | 5460 |
FAM50B,EMC2,RNF10,RNF34,BACH1,SSR3,EMC8,NSG1,UFL1,FKBP8,PIAS1,DAD1,TUSC3,TNRC6C,PGRMC1,CCDC47,DDX39A,HSP90B1,SSR1,PICALM,RPN1,VAPB,JUP,STT3A,CYB5A,MYBL2,PLAGL1,TMED9,TMPO,CDK9,RAB11A,RAB5C,RAB2A,HMOX2,FAM241A,TIA1,POR,RAB3A,CNN3 |
| 4.172e-02 | -3.18 | CSNK2A3 (casein kinase 2 alpha 3) | protein interactions | 283106 | 108 | 39 | 19454 | 5460 |
NKAPD1,PML,YAF2,RNF113A,RING1,NUCKS1,THRAP3,UFL1,RBBP7,PCGF3,EIF3E,MBD3,SAP30BP,SF3A1,EIF3J,H2AX,DDX39A,METTL14,ADNP,MTA2,EIF3K,CD274,OPTN,CSNK2B,WDR82,NKAP,FBXO22,RBBP4,ERH,DEK,SRC,ZNF687,IFI16,EIF3D,DDRGK1,MTPN,PIP4K2C,EIF3G,OSBPL8 |
| 4.178e-02 | -3.18 | endoplasmic reticulum quality control compartment | cellular component | GO:0044322 | 15 | 8 | 19108 | 5553 |
EDEM3,EDEM2,CALR,EDEM1,SYVN1,ERLEC1,SEC61B,DERL1 |
| 4.178e-02 | -3.18 | BLOC-1 complex | cellular component | GO:0031083 | 15 | 8 | 19108 | 5553 |
BCAS4,SNAPIN,BLOC1S2,KXD1,BLOC1S3,STX12,SNAP25,BLOC1S5 |
| 4.178e-02 | -3.18 | TM4_1 | prosite domains | PS00421 | 21 | 10 | 12186 | 3388 |
TSPAN5,CD151,TSPAN3,TSPAN7,TSPAN17,TSPAN10,CD9,CD63,CD81,TSPAN18 |
| 4.188e-02 | -3.17 | FHL3 (four and a half LIM domains 3) | protein interactions | 2275 | 273 | 90 | 19454 | 5460 |
SLU7,FOS,P4HA2,HSPA8,MYOZ3,CCND3,LNX2,PRR5L,RASL12,CDKN1A,LMO4,KLF3,ADNP,MMP14,LARP4B,NFKBIB,KTI12,HAPLN2,PHF21A,ACTB,LMO2,CDKN2D,CUL3,THAP7,SNRPB,SRGN,ZYX,FHL3,ZBTB16,LASP1,CCAR1,RAD21,SUPT5H,EZH2,ITGB5,TMEM14B,FOSL2,KDM2A,LHB,FAM222B,PML,PIAS1,POLR1H,SAP30BP,NDUFAB1,TTLL10,HYAL2,KLF12,PAK5,ZMYM6,PTP4A2,SDCBP,RNF146,SH3GLB2,CREB1,HYCC1,TMSB4X,CIMAP1B,QSER1,TRIM27,TMEM108,UBE2I,DUSP10,GARIN6,MORF4L1,TRAF3IP2,EXOSC1,SMAD2,PPIG,TMX3,CNOT7,EIF4EBP2,CRYBA2,RIGI,SNRPG,AURKAIP1,DDX39A,ZMYM4,GUCD1,MSRB3,SMAD3,DLGAP4,TES,PLEKHF2,KCTD3,RBM42,BARX2,SLC25A46,SMAD4,TOPBP1 |
| 4.189e-02 | -3.17 | COMM | interpro domains | IPR017920 | 10 | 6 | 18521 | 5414 |
COMMD2,COMMD5,COMMD3,COMMD9,COMMD8,COMMD6 |
| 4.189e-02 | -3.17 | Metalthion_vert_metal_BS | interpro domains | IPR018064 | 10 | 6 | 18521 | 5414 |
MT3,MT1M,MT1X,MT1A,MT2A,MT1E |
| 4.189e-02 | -3.17 | CRIB_dom_sf | interpro domains | IPR036936 | 10 | 6 | 18521 | 5414 |
CDC42SE1,PAK2,CDC42SE2,PAK6,PAK5,WASL |
| 4.189e-02 | -3.17 | CTLH_C | interpro domains | IPR006595 | 10 | 6 | 18521 | 5414 |
RMND5B,SMU1,RANBP10,GID8,MKLN1,MAEA |
| 4.189e-02 | -3.17 | Bcl-2_BH1-3 | interpro domains | IPR046371 | 10 | 6 | 18521 | 5414 |
BCL2A1,BOK,MCL1,BAK1,BCL2L1,BAX |
| 4.189e-02 | -3.17 | Emp24-like | interpro domains | IPR015720 | 10 | 6 | 18521 | 5414 |
TMED5,TMED7,TMED3,TMED4,TMED1,TMED9 |
| 4.207e-02 | -3.17 | DIDO1 (death inducer-obliterator 1) | protein interactions | 11083 | 159 | 55 | 19454 | 5460 |
FBXW7,PSENEN,HCFC2,SIRT7,BAP1,SNRPA,RPA3,WWP1,RPA2,MACROH2A2,KRT7,TPT1,EHHADH,IFI6,TNPO3,APEX1,SRPK2,VIRMA,EZH1,CCNF,MACROH2A1,CSNK2B,PEA15,CUL3,MYC,SNRPB,MCM3,AR,ANAPC15,HNRNPK,KRAS,H3C1,ERLEC1,DPM2,SSRP1,RUSF1,SRSF7,DHX9,PDHA1,ZC4H2,TMEM14B,POLR2C,H2AJ,FBP1,RAF1,JUN,TOP1,SUMO2,KLK3,PTP4A3,SRSF1,EED,ANKRD50,UQCR11,WWP2 |
| 4.208e-02 | -3.17 | molecular function inhibitor activity | molecular function | GO:0140678 | 514 | 172 | 18094 | 5411 |
FURIN,YWHAG,CAMK2N2,CLEC12B,HYAL2,CDKN2C,PPP1R8,PPP1R17,CSTB,SERPINB9,SERPINB6,SLCO1B3,PRPSAP1,ROCK1,ANXA4,ARPP19,DKK1,ZNF451,SERPIND1,LGALS3,PHACTR1,STOM,RPL23,TCF23,LCN1,CSTA,NFKBIA,SERPINB1,DFFA,RPS15,ELFN2,LILRB4,PEBP1,PPME1,UCN,ELFN1,TIMP3,DUSP19,PTN,SFN,RTKN,TXNIP,YWHAB,ABCE1,TANK,AKT1,HEXIM2,FKBP1A,FAF2,PPP1R1B,TIMP1,KCNMB2,NKX3-1,NCK1,GAPDH,OAZ3,SOST,CST3,RHOH,DKK3,SCG5,PRNP,SERPINI1,WFDC13,DYNLL1,HSPB1,SERPINH1,SERPINA3,ATP5IF1,BIRC5,SPINK9,CHP1,GPIHBP1,PACSIN3,ESR2,PCSK9,ATP2B4,SPINT2,CDKN1A,WFDC5,CCAR2,BEX3,LYNX1,OAZ1,STX7,CAMK2N1,ADRM1,SPRED1,SCN1B,APOC2,NFKBIL1,PPP1R26,CAV1,SERPINA5,SNIP1,SPOCK1,VTI1B,LYAR,PKIG,PI16,VAMP8,ID1,SNCB,LRP6,CST11,RPS7,TESC,SOCS3,SERPINB11,PPP1R16A,SPINK13,TMBIM6,TIMP4,CDKN1B,SPRED2,PPP1R12A,SIN3A,SERPINC1,IL18BP,OAZ2,PPP1R1A,LAMP2,PKIA,HEXIM1,LXN,BST2,DDIT3,UGT1A1,RPS20,LYPD6,PPP1R10,PPP1R27,PTTG1,MACROH2A1,MDFI,PI15,DNAJC3,FLCN,PPP1R2,SERPINA1,CCL5,RGS2,KCNAB1,FKBP1B,SCN3B,SLPI,PDE6D,LY6H,PLN,REG1A,MTRNR2L3,PROS1,TRIB1,PPP1R11,CDKN2D,TFPI,PI3,ID4,MTRNR2L7,GSKIP,CDC42SE1,STX1A,SH3BP5L,SERPINB10,GNAZ,MRLN,STX8,PKIB,SPOP,CAV3,USP14,CFTR |
| 4.209e-02 | -3.17 | somatic stem cell population maintenance | biological process | GO:0035019 | 56 | 23 | 18204 | 5365 |
POU5F1,MED27,SFRP1,FGF10,VPS72,MED17,BCL9,RBPJ,BMPR1A,LDB2,RAF1,MED21,NOG,KLF4,KLF10,KIT,SOX9,LDB1,MED30,SOX2,WNT7A,NR2E1,NKAP |
| 4.209e-02 | -3.17 | modulation by symbiont of entry into host | biological process | GO:0052372 | 56 | 23 | 18204 | 5365 |
TRIM5,IFNA2,NECTIN2,CD4,TRIM21,TRIM26,SNX3,HS3ST5,ITGAV,CH25H,TRIM10,TRIM34,TRIM22,HMGB1,TRIM6,TRIM8,TRIM62,FURIN,TRIM68,EXOC2,CXCL8,TRIM11,CAV1 |
| 4.217e-02 | -3.17 | CEACAM21 (CEA cell adhesion molecule 21) | protein interactions | 90273 | 80 | 30 | 19454 | 5460 |
MOXD1,HSPA13,FGFR1,GOLGA5,MET,TOR3A,FUT8,TMEM59,EPHA4,CNTN1,CEACAM5,RIGI,DDR1,ITM2B,EFNB1,NCR3LG1,EXOC8,TMEM30A,DAG1,LRRC24,SRC,RABIF,GLT8D1,PTK7,ITGA6,PCDH9,HS3ST1,NECTIN2,OAF,ODR4 |
| 4.217e-02 | -3.17 | TRIM9 (tripartite motif containing 9) | protein interactions | 114088 | 80 | 30 | 19454 | 5460 |
EXOC1,NTAQ1,CUL2,USP2,CUL3,TRIM8,NFKB1,SSX2IP,FBXW11,MUL1,TRIM27,DUSP6,ACTA2,UBE2G2,MDM2,ACTB,SNAP25,TRIM46,SPG21,TUBA1A,SIPA1L1,TBK1,GFM2,RELL2,ZC3H7A,HSPA8,MNAT1,UTP25,SEMA4C,PCGF3 |
| 4.217e-02 | -3.17 | ACP2 (acid phosphatase 2, lysosomal) | protein interactions | 53 | 80 | 30 | 19454 | 5460 |
YWHAG,MBLAC2,GPR85,KDSR,HSP90AA1,NIF3L1,PDCD1,LGALS8,TM4SF18,LHFPL4,CMBL,TMEM74,GPR173,S1PR4,HSP90AB1,AKR1C2,VTI1B,LGALS3,ATP6V0E1,STX12,P2RY12,RNF133,OPA3,LPAR2,STX7,RIGI,TNF,SLC7A1,SLC31A1,LPAR1 |
| 4.217e-02 | -3.17 | GPRIN1 (G protein regulated inducer of neurite outgrowth 1) | protein interactions | 114787 | 80 | 30 | 19454 | 5460 |
ARF6,RHOJ,ACTB,FBXO22,STX6,CAV1,VIRMA,RAB35,GJA1,RAC2,LAMTOR1,RHOG,RHOB,STAMBPL1,HNRNPD,RAB11A,DNAJC5,KRAS,CERS2,STX7,FLOT1,RHOU,TMEM185A,TUBB4B,FGFR1,RELL2,ARL15,SEC62,CDC42,DDX39A |
| 4.217e-02 | -3.17 | MAZ (MYC associated zinc finger protein) | protein interactions | 4150 | 80 | 30 | 19454 | 5460 |
RC3H2,H2AC4,TIAM1,SNRNP70,UBE2H,CUL3,MOV10,MYC,DDRGK1,YWHAH,YWHAG,CSNK2A1,TAX1BP1,FZR1,APEX1,ZNF330,RPA2,EZH2,NOTCH2,RAF1,CDK7,JUN,TOLLIP,STAU1,UFL1,FOS,RPA3,EP300,PICK1,EWSR1 |
| 4.217e-02 | -3.17 | HMGN4 (high mobility group nucleosomal binding domain 4) | protein interactions | 10473 | 80 | 30 | 19454 | 5460 |
HNRNPC,RPF2,SMARCA5,USP14,FTSJ3,BRD3,PARP2,RPL8,H2AZ1,MACROH2A1,PRKRA,RPF1,HPF1,SURF6,DKC1,E2F4,TOP3B,MAK16,EZH2,H2BC11,MACROH2A2,XRCC5,PMAIP1,H2BC12,EWSR1,STAU1,H3C1,PAK1IP1,RPS15,SSRP1 |
| 4.222e-02 | -3.16 | ERMP1 (endoplasmic reticulum metallopeptidase 1) | protein interactions | 79956 | 143 | 50 | 19454 | 5460 |
GPM6A,LPAR1,GPC1,EMC1,TMEM106B,TSPAN15,RPA3,VIPR1,GP9,RPA2,LMNA,PDCD1LG2,PGRMC1,ERVFRD-1,HCST,STAT5A,ESR2,S1PR4,SLC23A2,ST8SIA5,GPR173,CLDN9,TYROBP,GPR17,TM9SF4,RHCG,SLC7A14,HS2ST1,EMC2,BSCL2,LPAR2,CA14,CRELD1,CCDC47,TMEM45A,ISG15,ASIC1,FNDC9,NUP35,TMEM237,CD1A,SSMEM1,ASIC2,AQP2,CDH13,UPK1A,PTDSS1,CD200R1,CCR6,YWHAH |
| 4.224e-02 | -3.16 | Thenyldiamine H1-Antihistamine Action | SMPDB pathways | SMP0062624 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Tripelennamine H1-Antihistamine Action | SMPDB pathways | SMP0057587 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,GNG2,GNB1,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Bamipine H1-Antihistamine Action | SMPDB pathways | SMP0062882 | 8 | 6 | 1369 | 531 |
PRKCB,GNAQ,NFKB1,PLCB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Mirtazapine H1-Antihistamine Action | SMPDB pathways | SMP0062885 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,PLCB1,GNAQ,NFKB1,PRKCB |
| 4.224e-02 | -3.16 | Brompheniramine H1-Antihistamine Action | SMPDB pathways | SMP0057579 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Acrivastine H1-Antihistamine Action | SMPDB pathways | SMP0059881 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Diphenylpyraline H1-Antihistamine Action | SMPDB pathways | SMP0058908 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Fexofenadine H1-Antihistamine Action | SMPDB pathways | SMP0060218 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Tritoqualine H1-Antihistamine Action | SMPDB pathways | SMP0062895 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Emedastine H1-Antihistamine Action | SMPDB pathways | SMP0061040 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Diphenhydramine H1-Antihistamine Action | SMPDB pathways | SMP0058785 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNB1,GNG2,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Tolpropamine H1-Antihistamine Action | SMPDB pathways | SMP0062621 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Epinastine H1-Antihistamine Action | SMPDB pathways | SMP0061191 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Olopatadine H1-Antihistamine Action | SMPDB pathways | SMP0060740 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,PRKCB,GNG2,GNB1,PLCB1 |
| 4.224e-02 | -3.16 | Isothipendyl H1-Antihistamine Action | SMPDB pathways | SMP0059716 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Phenyltoloxamine H1-Antihistamine Action | SMPDB pathways | SMP0058916 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Cetirizine H1-Antihistamine Action | SMPDB pathways | SMP0059058 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Oxatomide H1-Antihistamine Action | SMPDB pathways | SMP0059044 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,NFKB1,GNAQ,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Quifenadine H1-Antihistamine Action | SMPDB pathways | SMP0060743 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNG2,GNB1,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Hydroxyethylpromethazine H1-Antihistamine Action | SMPDB pathways | SMP0059710 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,PLCB1,GNAQ,NFKB1,PRKCB |
| 4.224e-02 | -3.16 | Loratadine H1-Antihistamine Action | SMPDB pathways | SMP0060195 | 8 | 6 | 1369 | 531 |
PRKCB,NFKB1,GNAQ,PLCB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Desloratadine H1-Antihistamine Action | SMPDB pathways | SMP0060201 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Chlorphenoxamine H1-Antihistamine Action | SMPDB pathways | SMP0058903 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,PLCB1,NFKB1,GNAQ,PRKCB |
| 4.224e-02 | -3.16 | Phenindamine H1-Antihistamine Action | SMPDB pathways | SMP0061190 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Rupatadine H1-Antihistamine Action | SMPDB pathways | SMP0060235 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,PRKCB,GNG2,GNB1,PLCB1 |
| 4.224e-02 | -3.16 | Azelastine H1-Antihistamine Action | SMPDB pathways | SMP0060741 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Pheniramine H1-Antihistamine Action | SMPDB pathways | SMP0056662 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,GNG2,GNB1,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Histapyrrodine H1-Antihistamine Action | SMPDB pathways | SMP0058732 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,PRKCB,GNB1,GNG2,PLCB1 |
| 4.224e-02 | -3.16 | Ketotifen H1-Antihistamine Action | SMPDB pathways | SMP0059868 | 8 | 6 | 1369 | 531 |
PRKCB,GNAQ,NFKB1,PLCB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Carbinoxamine H1-Antihistamine Action | SMPDB pathways | SMP0058797 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Latrepirdine H1-Antihistamine Action | SMPDB pathways | SMP0062623 | 8 | 6 | 1369 | 531 |
PRKCB,NFKB1,GNAQ,PLCB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Chloropyramine H1-Antihistamine Action | SMPDB pathways | SMP0057585 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Pyrrobutamine H1-Antihistamine Action | SMPDB pathways | SMP0062887 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,PRKCB,GNG2,GNB1,PLCB1 |
| 4.224e-02 | -3.16 | Dimetindene H1-Antihistamine Action | SMPDB pathways | SMP0057582 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Thonzylamine H1-Antihistamine Action | SMPDB pathways | SMP0058769 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Terfenadine H1-Antihistamine Action | SMPDB pathways | SMP0060208 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Betahistine H1-Antihistamine Action | SMPDB pathways | SMP0060744 | 8 | 6 | 1369 | 531 |
PRKCB,NFKB1,GNAQ,PLCB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Ebastine H1-Antihistamine Action | SMPDB pathways | SMP0060204 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Clemastine H1-Antihistamine Action | SMPDB pathways | SMP0058891 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Alimemazine H1-Antihistamine Action | SMPDB pathways | SMP0059689 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Clocinizine H1-Antihistamine Action | SMPDB pathways | SMP0062788 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Talastine H1-Antihistamine Action | SMPDB pathways | SMP0057586 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,GNG2,GNB1,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Mepyramine H1-Antihistamine Action | SMPDB pathways | SMP0057583 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNG2,GNB1,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Buclizine H1-Antihistamine Action | SMPDB pathways | SMP0058964 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,NFKB1,GNAQ,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Bilastine H1-Antihistamine Action | SMPDB pathways | SMP0060170 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,PLCB1,GNAQ,NFKB1,PRKCB |
| 4.224e-02 | -3.16 | Flunarizine H1-Antihistamine Action | SMPDB pathways | SMP0061047 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,PLCB1,GNAQ,NFKB1,PRKCB |
| 4.224e-02 | -3.16 | Dexbrompheniramine H1-Antihistamine Action | SMPDB pathways | SMP0057580 | 8 | 6 | 1369 | 531 |
PRKCB,NFKB1,GNAQ,PLCB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Alcaftadine H1-Antihistamine Action | SMPDB pathways | SMP0062881 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Oxomemazine H1-Antihistamine Action | SMPDB pathways | SMP0059738 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,PRKCB,GNG2,GNB1,PLCB1 |
| 4.224e-02 | -3.16 | Bromodiphenhydramine H1-Antihistamine Action | SMPDB pathways | SMP0058813 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Thenalidine H1-Antihistamine Action | SMPDB pathways | SMP0062894 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNG2,GNB1,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Chlorcyclizine H1-Antihistamine Action | SMPDB pathways | SMP0058931 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,GNG2,GNB1,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Cinnarizine H1-Antihistamine Action | SMPDB pathways | SMP0059110 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNG2,GNB1,GNAQ,NFKB1 |
| 4.224e-02 | -3.16 | Orphenadrine H1-Antihistamine Action | SMPDB pathways | SMP0058808 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Embramine H1-Antihistamine Action | SMPDB pathways | SMP0062622 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,PLCB1,NFKB1,GNAQ,PRKCB |
| 4.224e-02 | -3.16 | Propiomazine H1-Antihistamine Action | SMPDB pathways | SMP0062625 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,PRKCB,GNG2,GNB1,PLCB1 |
| 4.224e-02 | -3.16 | Quetiapine H1-Antihistamine Action | SMPDB pathways | SMP0062884 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,PLCB1,NFKB1,GNAQ,PRKCB |
| 4.224e-02 | -3.16 | Phenbenzamine H1-Antihistamine Action | SMPDB pathways | SMP0059702 | 8 | 6 | 1369 | 531 |
PRKCB,NFKB1,GNAQ,PLCB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Mizolastine H1-Antihistamine Action | SMPDB pathways | SMP0060230 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Doxepin H1-Antihistamine Action | SMPDB pathways | SMP0059872 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,NFKB1,GNAQ,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Chlorphenamine H1-Antihistamine Action | SMPDB pathways | SMP0056661 | 8 | 6 | 1369 | 531 |
GNAQ,NFKB1,PRKCB,GNB1,GNG2,PLCB1 |
| 4.224e-02 | -3.16 | Cyclizine H1-Antihistamine Action | SMPDB pathways | SMP0058923 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,NFKB1,GNAQ,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Mequitazine H1-Antihistamine Action | SMPDB pathways | SMP0059720 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,PLCB1,GNAQ,NFKB1,PRKCB |
| 4.224e-02 | -3.16 | Meclizine H1-Antihistamine Action | SMPDB pathways | SMP0058956 | 8 | 6 | 1369 | 531 |
PRKCB,NFKB1,GNAQ,PLCB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Methdilazine H1-Antihistamine Action | SMPDB pathways | SMP0059730 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Bepotastine H1-Antihistamine Action | SMPDB pathways | SMP0060058 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,PLCB1,GNAQ,NFKB1,PRKCB |
| 4.224e-02 | -3.16 | Methapyrilene H1-Antihistamine Action | SMPDB pathways | SMP0058741 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Fenethazine H1-Antihistamine Action | SMPDB pathways | SMP0059707 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,PLCB1,NFKB1,GNAQ,PRKCB |
| 4.224e-02 | -3.16 | Antazoline H1-Antihistamine Action | SMPDB pathways | SMP0057584 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Homochlorcyclizine H1-Antihistamine Action | SMPDB pathways | SMP0062795 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Thiazinamium H1-Antihistamine Action | SMPDB pathways | SMP0060742 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Promethazine H1-Antihistamine Action | SMPDB pathways | SMP0059211 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,PRKCB,GNG2,GNB1,PLCB1 |
| 4.224e-02 | -3.16 | Hydroxyzine H1-Antihistamine Action | SMPDB pathways | SMP0058936 | 8 | 6 | 1369 | 531 |
PRKCB,GNAQ,NFKB1,PLCB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Deptropine H1-Antihistamine Action | SMPDB pathways | SMP0062883 | 8 | 6 | 1369 | 531 |
PLCB1,GNB1,GNG2,PRKCB,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Astemizole H1-Antihistamine Action | SMPDB pathways | SMP0059897 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNG2,GNB1,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Doxylamine H1-Antihistamine Action | SMPDB pathways | SMP0058803 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Pimethixene H1-Antihistamine Action | SMPDB pathways | SMP0062886 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Cyproheptadine H1-Antihistamine Action | SMPDB pathways | SMP0059694 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNG2,GNB1,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Levocetirizine H1-Antihistamine Action | SMPDB pathways | SMP0059114 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,NFKB1,GNAQ,GNG2,GNB1 |
| 4.224e-02 | -3.16 | Mebhydrolin H1-Antihistamine Action | SMPDB pathways | SMP0061052 | 8 | 6 | 1369 | 531 |
PRKCB,PLCB1,GNB1,GNG2,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Azatadine H1-Antihistamine Action | SMPDB pathways | SMP0059865 | 8 | 6 | 1369 | 531 |
GNB1,GNG2,GNAQ,NFKB1,PRKCB,PLCB1 |
| 4.224e-02 | -3.16 | Levocabastine H1-Antihistamine Action | SMPDB pathways | SMP0060224 | 8 | 6 | 1369 | 531 |
PLCB1,GNB1,GNG2,PRKCB,NFKB1,GNAQ |
| 4.224e-02 | -3.16 | Triprolidine H1-Antihistamine Action | SMPDB pathways | SMP0057581 | 8 | 6 | 1369 | 531 |
PLCB1,GNB1,GNG2,PRKCB,GNAQ,NFKB1 |
| 4.224e-02 | -3.16 | Temelastine H1-Antihistamine Action | SMPDB pathways | SMP0062880 | 8 | 6 | 1369 | 531 |
PLCB1,PRKCB,GNAQ,NFKB1,GNB1,GNG2 |
| 4.224e-02 | -3.16 | Dexchlorpheniramine H1-Antihistamine Action | SMPDB pathways | SMP0056811 | 8 | 6 | 1369 | 531 |
NFKB1,GNAQ,GNB1,GNG2,PLCB1,PRKCB |
| 4.224e-02 | -3.16 | Histamine H1 Receptor Activation | SMPDB pathways | SMP0063452 | 8 | 6 | 1369 | 531 |
GNG2,GNB1,NFKB1,GNAQ,PRKCB,PLCB1 |
| 4.228e-02 | -3.16 | FUBP3 (far upstream element binding protein 3) | protein interactions | 8939 | 283 | 93 | 19454 | 5460 |
B3GNT2,RAF1,RBM12,TOP3B,ISG15,SOX2,PDHA1,GLE1,GTPBP1,HNRNPA2B1,LSM14A,PABPC1,ZC3H7A,NUP42,G3BP1,CCAR1,SAV1,CNOT2,HNRNPA1,CPEB1,NQO1,DDX1,HNRNPD,FBXO32,EED,KCTD10,FAM98A,NUP35,TANK,DUSP14,NUP62,LARP4B,FOXS1,EP300,AKAP1,HSPA8,YTHDF1,TGIF2LX,STAU1,FXR2,B9D2,G3BP2,CSRP1,MYC,DCAF4,LSM14B,LMBR1L,FOXP3,MBL2,MATR3,PRRC2A,YTHDF2,TNRC6C,TP53,GARRE1,ABCE1,SOS2,LSM4,ARF4,MOV10,GRSF1,COPS5,SNRNP70,SYNCRIP,AIFM1,CAND1,CDK9,RBMS2,XBP1,AGO1,RPA2,PAX9,DYRK2,SIRT7,RPA3,SMG5,LSM12,ELOF1,AATF,FOXA3,CEP85,CTSD,AR,TIA1,RC3H2,UBE2H,PAIP2,IGF2BP1,SMAP2,PSPC1,CCNF,PTEN,RPS20 |
| 4.234e-02 | -3.16 | VPS33A (VPS33A core subunit of CORVET and HOPS complexes) | protein interactions | 65082 | 237 | 79 | 19454 | 5460 |
VCPIP1,AGR2,SHC1,ELP6,HSPB8,LAMP3,ATG7,NDC80,UBXN6,LAMP2,KARS1,CDC5L,TRIM35,TNKS,MYBL2,CCDC127,WDCP,DNM2,TAB2,RAB4A,GDI2,NUDT19,TFRC,UBR7,SOX2,KIF1C,STRBP,TBK1,MACO1,NAA35,VPS16,ADD2,FKBP8,EIF3E,NUP42,TOLLIP,NUP107,HINT1,TRAFD1,SNX5,RIT1,BICD2,RC3H2,PKNOX1,CCDC22,ATG3,FBXW11,LAMTOR1,PHKA1,CUL3,DHPS,CEP97,RPGRIP1L,RHOJ,PPM1M,GIT2,SH3GLB2,VPS18,STX17,VIPAS39,RPA2,CDK1,CRYAB,ELP3,TOMM22,ATG4C,FBXO30,NRBF2,PSMC1,STX7,UFL1,SRSF2,RAB5A,RAB9A,GPHN,HDAC5,UPF3B,XRCC5,INPPL1 |
| 4.237e-02 | -3.16 | TAK1 activates NFkB by phosphorylation and activation of IKKs complex | REACTOME pathways | R-HSA-445989 | 29 | 14 | 10285 | 3229 |
DHX9,NFKB1,AGER,UBE2V1,TAB1,S100B,NFKBIA,MYD88,UBE2N,NFKBIB,IKBKB,TAB2,HMGB1,TRAF6 |
| 4.239e-02 | -3.16 | H15 | prosite domains | PS51504 | 13 | 7 | 12186 | 3388 |
HP1BP3,H1-6,H1-10,SHPRH,H1-3,H1-5,H1-1 |
| 4.239e-02 | -3.16 | SMALL_CYTOKINES_CXC | prosite domains | PS00471 | 13 | 7 | 12186 | 3388 |
CXCL10,CXCL9,CXCL11,CXCL3,CXCL1,CXCL8,CXCL13 |
| 4.239e-02 | -3.16 | human chr14q22.3 | chromosome location | human chr14q22.3 | 19 | 8 | 26134 | 5823 |
OTX2,EXOC5,AP5M1,NAA30,SOCS4,LGALS3,FBXO34,MAPK1IP1L |
| 4.239e-02 | -3.16 | human chr4p15.32 | chromosome location | human chr4p15.32 | 19 | 8 | 26134 | 5823 |
CD38,PROM1,FGFBP2,FGFBP1,TAPT1,CLRN2,LDB2,LAP3 |
| 4.245e-02 | -3.16 | oxygen binding | molecular function | GO:0019825 | 33 | 15 | 18094 | 5411 |
HBB,NGB,CYP17A1,SOD2,CYP1A1,HBE1,CYP3A5,ADGB,CYGB,CYP2C18,ALB,HBM,CYP26A1,HBA1,CYP2F1 |
| 4.247e-02 | -3.16 | BH1 | prosite domains | PS01080 | 8 | 5 | 12186 | 3388 |
BAX,BCL2L1,BAK1,BCL2A1,MCL1 |
| 4.247e-02 | -3.16 | BH2 | prosite domains | PS01258 | 8 | 5 | 12186 | 3388 |
BCL2A1,BAK1,MCL1,BCL2L1,BAX |
| 4.247e-02 | -3.16 | PIWI | prosite domains | PS50822 | 8 | 5 | 12186 | 3388 |
PIWIL2,PIWIL3,PIWIL4,PIWIL1,AGO1 |
| 4.254e-02 | -3.16 | mitochondrial electron transport, NADH to ubiquinone | biological process | GO:0006120 | 39 | 17 | 18204 | 5365 |
NDUFB5,NDUFB6,NDUFA4,NDUFB7,NDUFA5,NDUFV2,NDUFB8,NDUFA2,NDUFS3,NDUFS8,NDUFA1,NDUFB10,NDUFAB1,NDUFB4,NDUFS6,NDUFS2,NDUFC2 |
| 4.254e-02 | -3.16 | negative regulation of non-canonical NF-kappaB signal transduction | biological process | GO:1901223 | 39 | 17 | 18204 | 5365 |
MIR149,IFI35,CPNE1,CCN3,NLRP2,ADIPOR1,MIR9-1,LITAF,PYDC2,MIR21,MIR223,NMI,TRIM15,PPM1B,MIR204,NLRP3,MIR132 |
| 4.254e-02 | -3.16 | negative regulation of Notch signaling pathway | biological process | GO:0045746 | 39 | 17 | 18204 | 5365 |
NIBAN2,HEY2,YTHDF2,FBXW7,SLC35C1,EGFL7,DLK2,BEND6,NFKBIA,WWP2,MMP14,DLX1,TCIM,MIR1224,TSPAN15,AKT1,BCL6 |
| 4.254e-02 | -3.16 | cytochrome complex assembly | biological process | GO:0017004 | 39 | 17 | 18204 | 5365 |
COX14,UQCC6,COA1,COX10,PET117,COX16,TIMM21,UQCC2,TACO1,COA5,BCS1L,COX20,SLC25A46,UQCC3,COA4,COX17,COX19 |
| 4.254e-02 | -3.16 | fatty-acyl-CoA metabolic process | biological process | GO:0035337 | 39 | 17 | 18204 | 5365 |
ACSL4,FITM2,ELOVL3,ELOVL7,HACD1,PPT1,HACD2,TECR,ELOVL6,NUDT19,ELOVL4,FAR2,ACACA,SLC25A1,ELOVL1,NUDT7,ACAT1 |
| 4.254e-02 | -3.16 | regulation of natural killer cell activation | biological process | GO:0032814 | 39 | 17 | 18204 | 5365 |
IL12A,FGR,IL12B,TYROBP,IL18,PTPN22,JAK2,IL15,KLRD1,TOX,LEP,IL23A,IL15RA,KLRC2,RHBDD3,BLOC1S3,MIR130A |
| 4.258e-02 | -3.16 | MIRLET7E (microRNA let-7e) | protein interactions | 406887 | 105 | 38 | 19454 | 5460 |
TRA2A,NONO,HNRNPA1,KARS1,GRSF1,APOBEC3B,IGF2BP1,DDX1,CRTAP,DDX23,SF3B4,EIF2AK2,RBM5,MYEF2,CPSF1,SYNCRIP,CDC5L,MATR3,FAM98A,HNRNPL,SF3A1,STRBP,RBFOX2,SART3,RARS1,HNRNPH3,NUFIP2,RTCB,HNRNPH2,SF3B1,HNRNPA2B1,MARS1,G3BP2,HNRNPK,HNRNPF,CDC40,HNRNPA0,TRA2B |
| 4.258e-02 | -3.16 | MED26 (mediator complex subunit 26) | protein interactions | 9441 | 105 | 38 | 19454 | 5460 |
MED11,KRAS,PML,MED13L,TCEA1,EWSR1,MED23,CDK8,MED31,TAF2,TAF10,POLR2C,POLR2G,POLR2D,MED9,MED30,RPAP2,MED17,POLR2I,TAF11,EAF2,APEX1,POLR2B,CDK9,POLR2L,POLR2F,MED29,SMAD4,MED27,MED21,MED10,MAPRE1,TAF9,MED4,ZCCHC10,MED22,TAF7,RUNX1 |
| 4.261e-02 | -3.16 | WDR26 (WD repeat domain 26) | protein interactions | 80232 | 172 | 59 | 19454 | 5460 |
PIK3R1,CNOT2,DDX50,SPON1,INSYN1,GNG2,YWHAH,MRPL18,ARMC8,USP46,TSG101,EGLN3,LY6H,JPH4,RPS7,EMILIN3,SOX2,FAF2,ADAMTS1,NDUFS6,HBP1,MAEA,AKT2,MAP1B,FAF1,MRFAP1L1,RPS24,HAPSTR1,MKLN1,LECT2,MDC1,ZNF687,SFN,MRM2,CUL3,HTRA2,UBE2H,YPEL5,RPS26,CCNF,PHF21A,PLCB2,BMP1,CTSB,NDUFAF4,GNB1,DYRK1A,ESR2,ATG16L1,FGFR1,NDUFA5,PNO1,GID8,BAP1,GID4,DVL2,RMND5B,KDM1A,RANBP10 |
| 4.265e-02 | -3.15 | BTB | prosite domains | PS50097 | 138 | 48 | 12186 | 3388 |
KBTBD4,KBTBD3,KBTBD13,IVNS1ABP,KLHL12,ZBTB38,KLHL28,KLHL23,ZBTB16,KLHL15,ZBTB18,KLHL26,ZBTB17,KLHL24,KLHL22,TNFAIP1,ZBTB5,ZBTB26,KCTD10,KCTD9,KLHL32,NACC2,SPOP,ZBTB42,ZBTB2,BACH1,KLHL7,KBTBD2,ZBTB39,KBTBD6,RHOBTB1,CCIN,KLHL1,ZBTB6,ZBTB25,ENC1,KLHL25,SPOPL,ZBTB45,RHOBTB3,KLHL9,KLHL3,IPP,ZBTB14,ZBTB33,RCBTB1,KCTD3,BCL6 |
| 4.267e-02 | -3.15 | ATP transport | biological process | GO:0015867 | 20 | 10 | 18204 | 5365 |
SLC25A23,CD47,SLC25A24,SLC25A4,SLC25A5,SLC25A31,CALHM3,ANKH,SLC25A17,SLC25A42 |
| 4.267e-02 | -3.15 | growth hormone receptor signaling pathway | biological process | GO:0060396 | 20 | 10 | 18204 | 5365 |
PTPN1,GHR,JAK1,STAT5A,SOCS2,GH1,PIK3R1,JAK2,CSH1,STAT6 |
| 4.267e-02 | -3.15 | DNA strand elongation | biological process | GO:0022616 | 20 | 10 | 18204 | 5365 |
MCM4,NBN,RFC4,MCM3,LIG3,POLE3,PCNA,TERT,RFC3,POLD2 |
| 4.267e-02 | -3.15 | melanosome transport | biological process | GO:0032402 | 20 | 10 | 18204 | 5365 |
MKKS,RAB11A,RAB27A,RAB11B,ARL6,BLOC1S5,MREG,RAB1A,BBS5,BLOC1S3 |
| 4.267e-02 | -3.15 | response to nitric oxide | biological process | GO:0071731 | 20 | 10 | 18204 | 5365 |
CCNA2,AIFM1,HNRNPD,DPEP1,GUCY1B1,CCR7,TRAF2,TXN,ATP5F1A,CCL19 |
| 4.267e-02 | -3.15 | regulation of cellular response to hypoxia | biological process | GO:1900037 | 20 | 10 | 18204 | 5365 |
MIR145,CHCHD2,NFE2L2,DDAH1,MIR210,ROCK2,TMBIM6,MIR21,EPHA4,ENO1 |
| 4.267e-02 | -3.15 | lipoprotein localization | biological process | GO:0044872 | 20 | 10 | 18204 | 5365 |
VMP1,CD36,ZDHHC17,PRKCB,UNC119B,PPARG,SURF4,MIR130B,MIR301B,SAR1B |
| 4.267e-02 | -3.15 | negative regulation of myeloid cell apoptotic process | biological process | GO:0033033 | 20 | 10 | 18204 | 5365 |
SNAI2,MIRLET7B,MIF,EPO,CCL5,IRF7,CCR5,MAEA,SELENOS,ST6GAL1 |
| 4.267e-02 | -3.15 | positive regulation of transcription regulatory region DNA binding | biological process | GO:2000679 | 20 | 10 | 18204 | 5365 |
HAND2,GTF2B,TRAF6,RB1,IFNG,TRIM6,IGF1,DDRGK1,NIBAN2,PAX6 |
| 4.267e-02 | -3.15 | regulation of chemokine (C-X-C motif) ligand 2 production | biological process | GO:2000341 | 20 | 10 | 18204 | 5365 |
HMGB1,FOXP1,KLF4,TNF,MIF,MYD88,OAS1,TIRAP,TLR4,MIR146A |
| 4.269e-02 | -3.15 | a6b1 and a6b4 Integrin signaling | Pathway Interaction DB | a6b1_a6b4_integrin_pathway | 31 | 16 | 2226 | 782 |
PIK3R1,MET,ITGA6,SHC1,PIK3CA,PMP22,PRKCA,AKT1,YWHAZ,YWHAB,YWHAG,CD9,HRAS,IL1A,SFN,YWHAH |
| 4.274e-02 | -3.15 | Bcl-2 | pfam domains | PF00452 | 10 | 6 | 17795 | 5224 |
MCL1,BCL2L1,BCL2A1,BAX,BOK,BAK1 |
| 4.274e-02 | -3.15 | EMP24_GP25L | pfam domains | PF01105 | 10 | 6 | 17795 | 5224 |
TMED9,TMED4,TMED7,TMED3,TMED1,TMED5 |
| 4.274e-02 | -3.15 | COMM_domain | pfam domains | PF07258 | 10 | 6 | 17795 | 5224 |
COMMD9,COMMD2,COMMD8,COMMD5,COMMD3,COMMD6 |
| 4.277e-02 | -3.15 | LRRC41 (leucine rich repeat containing 41) | protein interactions | 10489 | 77 | 29 | 19454 | 5460 |
FLYWCH2,RPA3,DERL1,AKAP1,COIL,CCND1,COX4I2,RNF7,RPA2,EEF1AKMT3,ZNF330,KRTAP3-1,CCNF,DCUN1D1,HNRNPL,APEX1,ESR2,EGLN3,GPR17,CUL3,ERCC3,ELOC,DDRGK1,LCN8,LMNB1,SPCS3,DRG1,EXOC8,POU5F1 |
| 4.277e-02 | -3.15 | CT45A5 (cancer/testis antigen family 45 member A5) | protein interactions | 441521 | 77 | 29 | 19454 | 5460 |
KBTBD6,COPS7B,COPS2,OSBPL8,UBE2H,ARMC8,PIP4K2C,NOS1AP,COPS5,CSNK2A1,GMNN,CREB3,COPS7A,RANBP10,CXXC1,UTP25,AHCYL1,TRIM26,NAP1L3,SF3B1,PPM1G,S100B,SNAPC1,GPBP1L1,PPME1,IFT22,PPP4C,SDCBP,SUPT5H |
| 4.280e-02 | -3.15 | positive regulation of oligodendrocyte differentiation | biological process | GO:0048714 | 28 | 13 | 18204 | 5365 |
CXCR4,PTPRZ1,PRMT5,NKX6-2,ZNF365,PTN,TNFRSF1B,RHEB,ASPA,DAG1,TLR2,MYRF,IL34 |
| 4.280e-02 | -3.15 | negative regulation of glial cell differentiation | biological process | GO:0045686 | 28 | 13 | 18204 | 5365 |
MECP2,DLX1,MIR181C,LDLR,NR2E1,GPR37L1,DUSP10,DRD3,ID4,F2,NOG,NKX6-2,CTNNB1 |
| 4.280e-02 | -3.15 | positive regulation of G2/M transition of mitotic cell cycle | biological process | GO:0010971 | 28 | 13 | 18204 | 5365 |
SMARCD3,CDC7,DTL,SIN3A,RRM1,WNT10B,CDK1,VPS4B,CCND1,MTA3,CCNB1,RAB11A,CDK4 |
| 4.280e-02 | -3.15 | positive regulation of antigen receptor-mediated signaling pathway | biological process | GO:0050857 | 28 | 13 | 18204 | 5365 |
CD81,RPS3,CD226,STAP1,SLC39A10,NECTIN2,BCL10,RAB29,CCR7,PRKCB,FOXP1,LIPA,TESPA1 |
| 4.280e-02 | -3.15 | startle response | biological process | GO:0001964 | 28 | 13 | 18204 | 5365 |
TUBA1A,DRD3,BACE1,DRD1,NPR2,UCN,MECP2,GLRB,CTNNA2,GLRA1,SLC6A3,COMT,PTEN |
| 4.280e-02 | -3.15 | lens fiber cell differentiation | biological process | GO:0070306 | 28 | 13 | 18204 | 5365 |
ATF4,PROX1,NF2,FZR1,TDRD7,EPHA2,SMAD3,CRYGB,TMOD1,CRYGD,WNT7A,SLC7A11,PLAAT3 |
| 4.284e-02 | -3.15 | CEBPB (CCAAT enhancer binding protein beta) | protein interactions | 1051 | 124 | 44 | 19454 | 5460 |
TOP3B,SOX2,JUN,CCL3,PPARG,CDK8,MED23,PDHA1,SMARCB1,KLC2,STAT6,HTR1A,ATF3,EP300,DDIT3,HMGB1,HNRNPK,EGR1,RIGI,HMGA1,NFKB1,MYC,CREBBP,SMARCA5,TNFAIP3,ATF4,RUNX1,AR,MCM3,SMAD4,BRCA1,TAF9,SP1,TRIB1,SMAD3,CREB1,DLST,HOMER3,RB1,CEBPG,STAT5A,ELK1,CDK9,NUP35 |
| 4.289e-02 | -3.15 | CCNC (cyclin C) | protein interactions | 892 | 185 | 63 | 19454 | 5460 |
PLEKHO2,RB1,TRAF3IP3,PRPF18,POLR2I,NDUFV2,SHC3,CISH,ERCC3,TEX12,MED4,HNRNPD,ZNF688,HSPB1,MED21,MED27,MED29,RBM41,BLOC1S2,GLUL,SOCS2,VTA1,SERPINA3,CKS1B,PNMA5,MED9,POLR2C,CDK8,NEFL,CALML5,GTF2F1,LORICRIN,POLR2B,ESR2,MGST3,TRIM54,MED17,RFC5,CREBBP,NDUFB7,MED22,CCHCR1,SERTAD3,MED10,TADA3,MED13L,FAM50B,MBD3,NRBF2,CDSN,FOXP2,AZGP1,MED11,UBE2K,FBXW7,CCNH,GPC4,MED30,FBXL19,FAM161A,MED31,MED23,RPA2 |
| 4.291e-02 | -3.15 | FGF | smart domains | SM00442 | 22 | 10 | 9717 | 2575 |
FGF16,FGF3,FGF12,FGF13,FGF1,FGF23,FGF7,FGF10,FGF22,FGF17 |
| 4.293e-02 | -3.15 | RGS19 (regulator of G protein signaling 19) | protein interactions | 10287 | 35 | 15 | 19454 | 5460 |
PSMA1,GNAI2,ESR2,OPRL1,OSTM1,SLC39A7,GNAO1,HINT1,PRKCA,NUFIP2,GNAI3,GNAZ,CNPY3,CSNK2A1,GDE1 |
| 4.293e-02 | -3.15 | PRTFDC1 (phosphoribosyl transferase domain containing 1) | protein interactions | 56952 | 35 | 15 | 19454 | 5460 |
TMEM14B,NIF3L1,HSD17B6,NTAQ1,SOX2,FCGR2A,SPG21,CNRIP1,STAT5A,MCMBP,EWSR1,GNPDA1,EEF2KMT,SPRED2,NFKBIA |
| 4.293e-02 | -3.15 | ZNF136 (zinc finger protein 136) | protein interactions | 7695 | 35 | 15 | 19454 | 5460 |
COIL,APEX1,S100B,RPL31,ZNF330,FBLN5,ZMYM2,NELL2,CBX3,PNMA2,STX1A,MDFI,NOTCH2,CUL3,CEP70 |
| 4.293e-02 | -3.15 | ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase) | protein interactions | 51099 | 35 | 15 | 19454 | 5460 |
KRAS,GAD2,COQ8A,SNRK,CCR1,SH3GLB1,TMEM14B,TMEM31,H2AC4,ZCCHC12,SKAP2,HMOX2,ATG16L1,TMEM38B,MIEF1 |
| 4.293e-02 | -3.15 | TNFSF10 (TNF superfamily member 10) | protein interactions | 8743 | 35 | 15 | 19454 | 5460 |
ACP5,HDAC5,IER3,TNFSF10,RBM42,ZDHHC17,HDAC3,CFTR,TRAF2,SOCS3,CUL3,CREBBP,TNFAIP3,SP1,PEA15 |
| 4.293e-02 | -3.15 | GDE1 (glycerophosphodiester phosphodiesterase 1) | protein interactions | 51573 | 35 | 15 | 19454 | 5460 |
RNF126,REEP6,CYB5B,UBAC2,ADCY2,HNRNPA1,DDX39A,RGS2,RGS19,XPNPEP1,HNRNPL,RGS1,ADRA1A,PLSCR1,RPA3 |
| 4.293e-02 | -3.15 | FAM120B (family with sequence similarity 120 member B) | protein interactions | 84498 | 35 | 15 | 19454 | 5460 |
EGLN3,SURF6,FLCN,ING2,CCNF,COP1,STN1,FEM1A,MTPN,TRAF2,TULP3,MYC,GSTM3,TNFAIP6,CUL3 |
| 4.293e-02 | -3.15 | SNRNP25 (small nuclear ribonucleoprotein U11/U12 subunit 25) | protein interactions | 79622 | 35 | 15 | 19454 | 5460 |
RIT1,MOV10,PFDN5,TRAF2,SNRPB,KRAS,FBXW7,OIP5,TRAF1,SF3B6,NKAPD1,ENO1,SF3B1,PICK1,SNRPD2 |
| 4.302e-02 | -3.15 | BGCRYSTALLIN | prints domains | PR01367 | 15 | 8 | 5227 | 1528 |
CRYGD,CRYGB,CRYBA1,CRYGA,CRYBA2,CRYBB2,CRYBB3,CRYBA4 |
| 4.304e-02 | -3.15 | positive regulation of monoatomic ion transmembrane transport | biological process | GO:0034767 | 155 | 56 | 18204 | 5365 |
OPRK1,STIM1,ATP1B1,F2,CCR2,MIR21,CFTR,NOS1AP,G6PD,AMIGO1,GSTO1,MIR210,NDUFA4,DRD1,KCNIP2,PLP1,FGF13,SRI,PPP3R2,COX17,CXCL10,NHERF1,NPSR1,CCL2,CAV1,TMSB4X,ACTN4,EDNRA,TESC,THY1,ADRB2,APLNR,KCNJ2,PPP3CA,STAC3,GSTM2,TRPC1,ATP1B3,BAX,SCN1B,BAK1,VMP1,MIR1-1,CXCL11,KCNMB1,IL13,LACRT,KCNC1,CACNB2,CXCL9,ABCB1,CX3CL1,CACNB3,CHP1,XCL1,IFNG |
| 4.307e-02 | -3.15 | regulatory ncRNA processing | biological process | GO:0070918 | 59 | 24 | 18204 | 5365 |
MAEL,SMAD3,TSN,HENMT1,SMAD1,DROSHA,ZC3H7A,AGO1,TDRD7,DDX5,NCBP2,TSNAX,TERT,PRKRA,PIWIL1,PIWIL3,SNIP1,SMAD2,PIWIL4,DGCR8,DDX4,HNRNPA2B1,PIWIL2,DICER1 |
| 4.313e-02 | -3.14 | fibroblast growth factor receptor binding | molecular function | GO:0005104 | 25 | 12 | 18094 | 5411 |
FGF1,FGF16,FGF7,NPTN,FRS3,FGF3,FGF23,FGF17,FLRT3,FGF22,FGF10,FLRT2 |
| 4.313e-02 | -3.14 | DNA exonuclease activity, producing 5'-phosphomonoesters | molecular function | GO:0016895 | 25 | 12 | 18094 | 5411 |
PLD3,MEIOB,RAD1,ISG20,DCLRE1C,MGME1,APEX1,REXO2,APTX,EXD2,FEN1,APEX2 |
| 4.318e-02 | -3.14 | PPIase_FKBP_dom | interpro domains | IPR001179 | 15 | 8 | 18521 | 5414 |
FKBP4,FKBP8,FKBP10,FKBP1B,AIP,FKBP2,FKBP1A,FKBP14 |
| 4.318e-02 | -3.14 | TRAF-like | interpro domains | IPR008974 | 15 | 8 | 18521 | 5414 |
SIAH2,TRAF6,SPOP,SPOPL,SIAH1,TRAF2,TRIM37,TRAF1 |
| 4.318e-02 | -3.14 | Beta/gamma_crystallin | interpro domains | IPR001064 | 15 | 8 | 18521 | 5414 |
CRYBA4,CRYBA1,CRYBB2,CRYBA2,CRYGA,CRYGD,CRYGB,CRYBB3 |
| 4.318e-02 | -3.14 | G_crystallin-like | interpro domains | IPR011024 | 15 | 8 | 18521 | 5414 |
CRYBB2,CRYBA4,CRYBA1,CRYBA2,CRYGA,CRYGD,CRYGB,CRYBB3 |
| 4.323e-02 | -3.14 | PALM2AKAP2 (PALM2 and AKAP2 fusion) | protein interactions | 445815 | 140 | 49 | 19454 | 5460 |
RAB11A,CSK,MYC,ATP5F1A,PRKACB,RHOB,NIF3L1,LAMTOR1,VMP1,RHOJ,ACTB,VIRMA,WDR77,PPP1CB,CDC42,FGFR1,PIH1D1,LACC1,PRKCA,PML,BAP1,RPL4,FBXW7,CERS2,HSPA5,STX7,BABAM1,DPP4,RHOG,RPS2,RAB35,RAC2,TES,GJA1,SPTAN1,ARF6,CAV1,DIRAS3,CHMP4C,NHERF1,CAPZA2,PDHA1,SART3,RND3,ZYX,CLPB,KRAS,TFG,FLOT1 |
| 4.323e-02 | -3.14 | PHC2 (polyhomeotic homolog 2) | protein interactions | 1912 | 140 | 49 | 19454 | 5460 |
FBLN5,ZMAT2,CSNK2B,SIAH1,TAB1,SCML2,MYC,LMO2,THAP7,PRPF31,MAPKAPK3,YAF2,PCGF2,RPL4,FXR2,KDM1A,FAM161A,LMO3,SDCBP,MFAP1,POLR2L,SYNCRIP,SMAD3,EED,RPL7,SUV39H1,H2AC4,NCK1,TMEM70,DRG1,BRD3,SSX2IP,FHL3,RING1,SCML1,TRIM63,KCTD17,CBX7,PCGF3,PCGF6,ENKD1,AP1M1,RAF1,TOP3B,MLLT6,SOX2,SFTPC,PHC1,CRKL |
| 4.333e-02 | -3.14 | SEPTIN6 (septin 6) | protein interactions | 23157 | 74 | 28 | 19454 | 5460 |
BICD2,AGR2,XPO1,TRIM32,VIRMA,PLEKHF2,HNRNPL,STAT1,CDC42EP3,HRAS,PPT1,FGFR1,EZH2,CFTR,MRPL12,CDC42,MORN4,HSPA5,CDC42EP4,KRAS,KDM1A,EP300,CDC42EP2,IGF1R,SEPTIN7,HAPSTR1,RPA3,RHOU |
| 4.333e-02 | -3.14 | PIGK (phosphatidylinositol glycan anchor biosynthesis class K) | protein interactions | 10026 | 74 | 28 | 19454 | 5460 |
NME2,FAM20C,COPE,ESR2,ST8SIA5,THY1,BST2,GRM2,GP9,VAPB,RPA2,RPN1,PLD3,PRKCA,PGRMC1,RAF1,CCDC47,TMEM106A,CLEC2B,LPAR1,EMC1,HSPA5,HS2ST1,TSPAN15,TMEM106B,GPAA1,RPA3,CPNE2 |
| 4.333e-02 | -3.14 | UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2) | protein interactions | 55757 | 74 | 28 | 19454 | 5460 |
TMEM106B,DNAJC3,HELLS,IGF1R,APPBP2,GPIHBP1,HSPA5,EDEM2,LY6H,PI15,CNPY3,NUDT12,CPE,SELENOF,LMBR1L,SEC61B,DNASE1L1,DNAJB9,CTSB,OS9,CUL3,BABAM1,EDEM1,DPP4,GGH,DNAJC10,UBE2H,CALU |
| 4.336e-02 | -3.14 | regulation of proteasomal protein catabolic process | biological process | GO:0061136 | 189 | 67 | 18204 | 5365 |
GCLC,PITHD1,CLU,PSMC1,USP13,STUB1,AKT1,HFE,NOP53,BAG2,SUMO2,FBXW7,GABARAP,SOCS4,CCAR2,SVIP,DDRGK1,MDM2,XPO1,UBE2K,ZFAND2A,USP38,RCHY1,CSNK1E,TAF9,ZER1,FHIT,LAMP3,FZR1,CDC20,NUPR1,GPX1,UBB,PSMC4,CAMLG,OPHN1,HECTD1,GABARAPL2,COP1,SOCS5,PSME1,RAD23B,DESI1,UFL1,AQP11,PSMC3,PIAS1,CSNK1A1,TRIB1,DNAJB2,PSME2,PSMD14,PSEN1,SGTA,MTM1,PSMD10,DET1,NFE2L2,PSMC5,CAV1,USP14,WNT10B,HSP90AB1,FBXO22,GSK3A,SUMO1,USP5 |
| 4.339e-02 | -3.14 | lower_back | COSMIC cancer mutations | lower_back | 40 | 17 | 16828 | 4835 |
SLC6A11,PIK3CA,SLC17A5,PTEN,GNA11,KIT,TP53,AKT1,PTPN11,FBXW7,GNAQ,BAP1,KRAS,SYT4,HRAS,PCDHB8,PIK3R1 |
| 4.341e-02 | -3.14 | axon | cellular component | GO:0030424 | 650 | 209 | 19108 | 5553 |
SNAPIN,NTRK2,PRKCB,NRSN1,SEPTIN6,STX1A,KIF3B,STAT1,CD2AP,ABITRAM,HAPLN2,ATP6AP2,FZD3,STXBP1,CTNNA2,MGARP,RAB3A,CHRM1,UHMK1,LGI3,BACE1,GAD2,SLC6A3,ADAM21,OTX2,FLRT3,TENM3,KCNJ11,PPFIA2,HSPA8,TAC1,SLC6A2,TRIM46,FEZ1,SRC,CRYAB,ADGRL3,L1CAM,SLC38A7,HOMER1,SLC1A1,NEO1,SLC38A1,CLDN11,MACO1,CD200,CDK5,PHB2,ARPC3,ATP1A1,TRAK2,MAP1B,ELK1,MUL1,DNM2,CNR1,KCNH1,CTNND1,NTF4,ACTB,PAFAH1B1,C9orf72,SMN1,GRM2,CD40,SLC4A10,MME,AMIGO1,SRSF10,GABRG2,CPLX1,HSP90AB1,LRRTM1,TNFRSF1B,DYNLL1,CFL1,SLC4A8,FGF13,SCN1B,SLC8A1,KIF1C,FBXW11,ELAVL4,KCNA3,ZC3H14,ALCAM,MTPN,CDK5R1,KCNC1,HSPB1,SYT4,COMT,SLC32A1,NRP1,NEFL,THY1,SYP,CBL,CYTH2,TMEM108,GHRL,EPS8,SSNA1,ARMCX3,CCSAP,CTTN,PRNP,OPRK1,NGDN,GPM6A,LGI1,EPHA4,ATP1A3,GABRA2,DLG1,ROGDI,KLHL24,PCDH9,TPBG,NCDN,SNCB,PNOC,HSP90AA1,KCNAB1,SYT2,BLOC1S3,PRSS12,KCNB1,DAG1,DLG4,SPOCK1,HTR2A,SNAP25,SIGMAR1,ITGA2,ADORA1,AP3S2,TGFB2,PPT1,CNTN2,HPCA,CRHBP,DYRK1A,SPTBN1,CYP17A1,DISC1,HDAC6,SMURF1,CSNK1E,ACTL9,STMN2,LRFN3,HSBP1,GABBR1,BAG2,C1QL1,MAP4,ADNP,MAP3K12,CPLX2,EXOC8,BLOC1S2,AZIN2,LRRC4B,ORAI2,EXOC3,SYBU,OPHN1,PDYN,ATL1,SLC6A1,SARM1,BLOC1S5,IGF2BP1,MT3,GSK3A,IGF1R,SOD1,GRIA1,UCN,RAB5A,FKBP4,CCN3,ATAT1,FAM168B,BMPR2,PTK7,SLC1A2,CPLX3,MTMR2,TIAM1,NETO1,CDH8,CALY,LAMP5,EMX2,CNTNAP1,SLC38A2,CNTN1,PSEN1,KCNA2,SNCG,CRMP1,NTNG2,NTRK3,TXNRD2,TBC1D24,OPRM1,RGS7BP |
| 4.344e-02 | -3.14 | PATJ (PATJ crumbs cell polarity complex component) | protein interactions | 10207 | 102 | 37 | 19454 | 5460 |
KCNJ2,KCNJ10,RHOB,PSMD14,YWHAH,ANAPC15,YWHAG,USP14,RAB32,WWP2,LIN7B,SAV1,GJB2,HOMER1,NLGN2,CRB3,VIRMA,ESR2,HNRNPL,PHYH,CINP,HRAS,HOMER3,CEP57L1,EEF1AKMT3,LURAP1,WWP1,RNF146,CD2AP,ATG16L1,FLOT1,PAX6,CAPZA1,KRAS,CLDN1,LIN7C,BAP1 |
| 4.344e-02 | -3.14 | RANBP3 (RAN binding protein 3) | protein interactions | 8498 | 102 | 37 | 19454 | 5460 |
DEDD,UBE2H,RPL24,YWHAG,XPO1,YWHAH,SAMHD1,AR,SNRPB,CTSD,MOV10,SFN,RANGRF,PPAT,LDLR,ALB,RAN,SWAP70,ACACA,RDH12,GPX7,PPARG,MORN4,TRAF2,RPL27A,SUPT5H,UGP2,DNAJC22,SAR1B,PAX6,CHN2,SMC4,DNAJB4,JADE1,SMARCD3,FAF1,PABPC1 |
| 4.344e-02 | -3.14 | WRN (WRN RecQ like helicase) | protein interactions | 7486 | 102 | 37 | 19454 | 5460 |
MOV10,CREBBP,CUL3,POLB,BRCA1,PTTG1,PAXX,CPSF1,EIF4A3,SUMO2,SNRNP40,MDM2,CDC5L,TOP3B,RAF1,FEN1,TP53,SUMO1,SOX2,H2AX,CDC42,TUBA1A,RPA2,RAD1,RPA3,RPL31,PML,POLD2,NBN,XRCC5,PCNA,DHX9,CTNNBL1,KRAS,POLL,MDC1,FTL |
| 4.344e-02 | -3.14 | Mad2l1 (MAD2 mitotic arrest deficient-like 1) | protein interactions | 56150 | 102 | 37 | 19454 | 5460 |
DAPK3,MGAT1,ATXN10,TUBB,CDC20,MAD2L1,BCCIP,STT3A,TRIM27,SEC61A1,TUBG1,ANAPC4,CDC23,PDF,PSMD3,CDC16,ATP5MG,PKP4,CDC26,UTP6,THRAP3,GPC1,CDCA7L,RPP14,POLA2,FKBP8,PYM1,NUDT5,PRIM2,SLC25A11,ATP5F1E,TCP11L1,DMAP1,TIMM23,MAD2L1BP,IDH2,LBR |
| 4.344e-02 | -3.14 | PMS1 (PMS1 homolog 1, mismatch repair system component) | protein interactions | 5378 | 102 | 37 | 19454 | 5460 |
SNRNP40,PSD2,TOP1,DYNLT3,CDK9,CDC5L,USP5,HRAS,VAMP3,PTTG1,USP13,UBXN6,MOV10,CUL3,NONO,SLC31A1,KPNA2,MCM6,PSMC1,RNF20,PYGB,MSH6,RFC2,RFC4,RPA3,PML,GNG5,PGK1,NUP50,RPA2,CAPN2,PSMC3,TP53,CDC42,RFXANK,PPP2R1A,H1-3 |
| 4.344e-02 | -3.14 | NCCRP1 (NCCRP1, F-box associated domain containing) | protein interactions | 342897 | 102 | 37 | 19454 | 5460 |
STK16,WTAP,APTX,E2F6,CCR1,STX17,CFTR,FTH1,FCF1,NUDT3,ST7,SOX2,B3GNT2,FANCG,DUSP21,DDI1,FBXW7,YAF2,SLC35F2,UCP2,HSPA8,DDX39B,AGPAT1,UPK1A,HNRNPA1,PTDSS1,ERCC3,MYC,ESR2,ATP6AP2,PRNP,GABPA,CFAP298,MCPH1,POLR2L,CD274,CCNF |
| 4.350e-02 | -3.13 | Cadmium Induces DNA Synthesis and Proliferation in Macrophages | SMPDB pathways | SMP0063805 | 20 | 12 | 1369 | 531 |
NFKB1,MYC,NFKBIA,HRAS,JUN,RAF1,PRKCB,PRKCA,TNF,MAP2K1,FOS,PLCB1 |
| 4.353e-02 | -3.13 | regulation of modification of postsynaptic structure | biological process | GO:0099159 | 10 | 6 | 18204 | 5365 |
CHMP2B,TIAM1,CAMKV,RHOB,CTTNBP2,CDC42 |
| 4.353e-02 | -3.13 | catechol-containing compound catabolic process | biological process | GO:0019614 | 10 | 6 | 18204 | 5365 |
MOXD1,PDE1B,COMT,SLC6A3,DBH,SULT1A3 |
| 4.353e-02 | -3.13 | adult feeding behavior | biological process | GO:0008343 | 10 | 6 | 18204 | 5365 |
GHRL,LEP,NPY,BRS3,USP46,CARTPT |
| 4.353e-02 | -3.13 | CD40 signaling pathway | biological process | GO:0023035 | 10 | 6 | 18204 | 5365 |
CD86,PHB2,TRAF3IP2,PHB1,CD40LG,CD40 |
| 4.353e-02 | -3.13 | regulation of mesodermal cell differentiation | biological process | GO:1905770 | 10 | 6 | 18204 | 5365 |
BMPR1A,GJA1,MIR200C,FGFR1,DKK1,MIR150 |
| 4.353e-02 | -3.13 | transferrin transport | biological process | GO:0033572 | 10 | 6 | 18204 | 5365 |
TFRC,RAB11B,REP15,MCOLN1,DNM2,ARHGAP1 |
| 4.353e-02 | -3.13 | retina vasculature morphogenesis in camera-type eye | biological process | GO:0061299 | 10 | 6 | 18204 | 5365 |
NRP1,NDP,RHOJ,CYP1B1,CLIC4,FZD4 |
| 4.353e-02 | -3.13 | positive regulation of ATP biosynthetic process | biological process | GO:2001171 | 10 | 6 | 18204 | 5365 |
PID1,TAFAZZIN,IL4,PPARA,TMSB4X,ENO1 |
| 4.353e-02 | -3.13 | ribonucleoside diphosphate biosynthetic process | biological process | GO:0009188 | 10 | 6 | 18204 | 5365 |
UMPS,GUK1,CMPK1,AK5,AK2,AK3 |
| 4.353e-02 | -3.13 | aminoglycoside antibiotic metabolic process | biological process | GO:0030647 | 10 | 6 | 18204 | 5365 |
AKR1C1,AKR7A2,AKR1B1,AKR1C2,CBR4,AKR1A1 |
| 4.353e-02 | -3.13 | leptin-mediated signaling pathway | biological process | GO:0033210 | 10 | 6 | 18204 | 5365 |
LEPR,MT3,UGCG,MKKS,LEP,ADIPOR1 |
| 4.353e-02 | -3.13 | endothelial cell chemotaxis | biological process | GO:0035767 | 10 | 6 | 18204 | 5365 |
NRP1,VEGFA,RAB13,CXCL13,CCN3,GAB1 |
| 4.353e-02 | -3.13 | phosphatidylglycerol biosynthetic process | biological process | GO:0006655 | 10 | 6 | 18204 | 5365 |
TAFAZZIN,GPAM,PLSCR3,TAMM41,PTPMT1,PGS1 |
| 4.353e-02 | -3.13 | I-kappaB phosphorylation | biological process | GO:0007252 | 10 | 6 | 18204 | 5365 |
TLR4,PRDX4,TLR7,IKBKB,TLR2,TLR3 |
| 4.353e-02 | -3.13 | endothelial cell activation | biological process | GO:0042118 | 10 | 6 | 18204 | 5365 |
PPIA,SMAD4,TCIM,FOXP1,CXCL10,PRMT5 |
| 4.353e-02 | -3.13 | pharyngeal arch artery morphogenesis | biological process | GO:0061626 | 10 | 6 | 18204 | 5365 |
EDNRA,NOG,FOLR1,BMPR2,BMPR1A,TGFB2 |
| 4.353e-02 | -3.13 | adenylate cyclase-activating dopamine receptor signaling pathway | biological process | GO:0007191 | 10 | 6 | 18204 | 5365 |
DRD3,GNG2,NHERF1,PTGER1,GNB1,DRD1 |
| 4.353e-02 | -3.13 | cellular response to parathyroid hormone stimulus | biological process | GO:0071374 | 10 | 6 | 18204 | 5365 |
FOS,SOST,HDAC6,WNT10B,FGF23,MEF2C |
| 4.353e-02 | -3.13 | cellular response to brain-derived neurotrophic factor stimulus | biological process | GO:1990416 | 10 | 6 | 18204 | 5365 |
NTRK2,GRIA1,TMEM108,EIF4A3,UBE3A,GAD2 |
| 4.353e-02 | -3.13 | dopamine catabolic process | biological process | GO:0042420 | 10 | 6 | 18204 | 5365 |
SLC6A3,DBH,COMT,PDE1B,MOXD1,SULT1A3 |
| 4.353e-02 | -3.13 | negative regulation of cholesterol biosynthetic process | biological process | GO:0045541 | 10 | 6 | 18204 | 5365 |
ERLIN2,MIR98,ERLIN1,MIR342,MIR185,SOD1 |
| 4.353e-02 | -3.13 | polyketide metabolic process | biological process | GO:0030638 | 10 | 6 | 18204 | 5365 |
AKR1C2,AKR1B1,AKR1A1,CBR4,AKR1C1,AKR7A2 |
| 4.353e-02 | -3.13 | doxorubicin metabolic process | biological process | GO:0044598 | 10 | 6 | 18204 | 5365 |
AKR1B1,AKR1C2,CBR4,AKR1A1,AKR1C1,AKR7A2 |
| 4.353e-02 | -3.13 | neuronal action potential propagation | biological process | GO:0019227 | 10 | 6 | 18204 | 5365 |
NTRK2,CACNB4,SCN1B,FKBP1B,ATP1A2,CNTNAP1 |
| 4.353e-02 | -3.13 | catecholamine catabolic process | biological process | GO:0042424 | 10 | 6 | 18204 | 5365 |
COMT,SLC6A3,DBH,MOXD1,PDE1B,SULT1A3 |
| 4.353e-02 | -3.13 | negative regulation of protein exit from endoplasmic reticulum | biological process | GO:0070862 | 10 | 6 | 18204 | 5365 |
DERL2,ERLEC1,UBAC2,OS9,SVIP,UBE2G2 |
| 4.353e-02 | -3.13 | action potential propagation | biological process | GO:0098870 | 10 | 6 | 18204 | 5365 |
CACNB4,NTRK2,CNTNAP1,ATP1A2,FKBP1B,SCN1B |
| 4.353e-02 | -3.13 | negative regulation of sterol biosynthetic process | biological process | GO:0106119 | 10 | 6 | 18204 | 5365 |
MIR98,ERLIN1,ERLIN2,MIR342,MIR185,SOD1 |
| 4.353e-02 | -3.13 | fibroblast apoptotic process | biological process | GO:0044346 | 10 | 6 | 18204 | 5365 |
CFDP1,CUL3,BAK1,MYC,API5,NUPR1 |
| 4.367e-02 | -3.13 | LGALS8 (galectin 8) | protein interactions | 3964 | 169 | 58 | 19454 | 5460 |
LRRC8C,BTF3,HSP90AA1,TRIM23,SLC1A1,ACP2,ESR2,TAX1BP1,CD47,TXN,LRRC8A,NDP,RAB14,PRDX2,CDC42,PDIA2,SLC12A2,FGFR1,GTF2IRD1,HSP90B1,SDCBP,ITGA2,TRIM22,TRIM5,WBP2,SOD1,HMGB1,NPTN,SLC31A1,DAG1,YWHAG,SLC38A9,SLC35A5,HDAC6,PRDX1,LAMP2,ATG9A,CD58,LYZ,NCR3LG1,LRRC4B,CD63,ITGA6,TMEM237,ALCAM,TRIM6,TBK1,RAF1,APEH,NUPR1,ENPP4,EZH2,SLC17A5,PDIA6,ATP2B4,OSTM1,TNFSF8,RRAGB |
| 4.381e-02 | -3.13 | OSBP (oxysterol binding protein) | protein interactions | 5007 | 121 | 43 | 19454 | 5460 |
KRAS,SACM1L,RAD21,ZRANB2,GNAI3,TP53,GFPT1,ACTN4,PLEKHA8,CAND1,SNAP25,WDR44,SWAP70,SEC23A,ESYT1,PSMD10,YWHAB,PPP3CA,CSNK2A1,COPS5,LRRTM1,B2M,RPA3,TTC1,EP300,KCTD12,RPA2,VAPB,KLC2,EIF4B,TBC1D17,WDR77,PGRMC1,PPP1CB,OTULINL,VIRMA,CCNF,CTNNA1,NTRK3,RIT1,NPTX1,SFN,SAMHD1 |
| 4.386e-02 | -3.13 | ARHGEF11 (Rho guanine nucleotide exchange factor 11) | protein interactions | 9826 | 71 | 27 | 19454 | 5460 |
RPRD1A,SSBP1,GSK3A,INA,FBXO22,TRMT61A,ESR2,VIRMA,MZT2B,ISCA2,COMMD9,NOA1,RHOB,PDF,TMOD2,MAP1B,LPAR2,LPAR1,TOP3B,MTX2,RFXANK,CDC42,PAK5,TMOD1,TFB1M,NUPR1,GNAQ |
| 4.386e-02 | -3.13 | ISCA2 (iron-sulfur cluster assembly 2) | protein interactions | 122961 | 71 | 27 | 19454 | 5460 |
SLMAP,DBT,PRNP,MOB4,SERPINC1,COX4I1,FXN,NTAQ1,MTPN,AKT1,FGFR1OP2,RNF41,EIF3E,KRAS,GUK1,SRI,SIKE1,MTHFD2L,THNSL1,MSRB3,APOBEC3C,CRYAB,ZMYM6,GUCD1,GLRX5,GABARAPL2,DUSP14 |
| 4.386e-02 | -3.13 | OSBPL6 (oxysterol binding protein like 6) | protein interactions | 114880 | 71 | 27 | 19454 | 5460 |
YWHAH,YWHAG,BLVRA,RHOB,YWHAZ,THTPA,CAMSAP2,YWHAB,EIF4E2,KCTD3,PHTF2,ILVBL,EGLN3,STX6,TRAF1,ERH,INPP5E,JPH4,SIPA1L1,OTULINL,KLRD1,VAPB,RPA2,RPA3,RTKN,KRAS,NOP53 |
| 4.386e-02 | -3.13 | SRA1 (steroid receptor RNA activator 1) | protein interactions | 10011 | 71 | 27 | 19454 | 5460 |
DHX9,DDIT3,HSPA8,HNRNPA2B1,FOS,PABPC1,ATF3,EGR1,SAP30,EGR2,DMTF1,BTG2,GTF2H2,GTF2B,SYNCRIP,CREB1,ESR2,ACTB,HNRNPL,GAPDH,ATF1,HNRNPA1,HNRNPAB,ATF4,HNRNPD,OAZ1,FOSL2 |
| 4.386e-02 | -3.13 | PIH1D2 (PIH1 domain containing 2) | protein interactions | 120379 | 71 | 27 | 19454 | 5460 |
COMMD3,LAP3,FRS3,SDCBP,TNNI1,DPH3,MRFAP1L1,TCEA2,KRTAP12-4,NFIL3,SERTAD1,NTAQ1,GPRASP2,BAG3,TTC23,MDFI,SPRED1,MCCD1,CDC23,ZNF688,SLPI,LMNB1,PLEKHJ1,ZMAT5,DES,RALA,EIF4A2 |
| 4.391e-02 | -3.13 | regulation of postsynaptic membrane neurotransmitter receptor levels | biological process | GO:0099072 | 62 | 25 | 18204 | 5365 |
LHFPL4,CACNG3,AP2A1,C1QL2,EPS8,NPTX1,DLG1,DLG4,DLG3,SNAP25,NETO1,HSP90AA1,CALY,C1QL3,RAP2A,CTNND1,SST,LGI1,RAB11A,AP2M1,GPHN,NETO2,AP2S1,NSG1,FRRS1L |
| 4.391e-02 | -3.13 | positive regulation of myeloid leukocyte differentiation | biological process | GO:0002763 | 62 | 25 | 18204 | 5365 |
MIR145,CREB1,CCR1,IL23A,RB1,FOS,HCLS1,TNF,TYROBP,IL5,NOTCH2,IFNG,IL12B,IL34,TESC,EEIG1,HAX1,CD4,TRIB1,CTNNBIP1,PPP3CA,RUNX1,PRKCA,KLF10,TRAF6 |
| 4.391e-02 | -3.13 | nuclear receptor signaling pathway | biological process | GO:0141193 | 62 | 25 | 18204 | 5365 |
ESR2,EGLN2,DDX5,PADI2,PHB1,JAK2,TAF7,RBFOX2,UBE3A,RNF14,CALR,WBP2,PHB2,NKX3-1,AR,CST11,YWHAH,PTGES3,TADA3,RWDD1,TRIP4,SRC,FKBP4,ERRFI1,PGR |
| 4.391e-02 | -3.13 | intracellular steroid hormone receptor signaling pathway | biological process | GO:0030518 | 62 | 25 | 18204 | 5365 |
PHB2,NKX3-1,AR,CST11,TADA3,RWDD1,TRIP4,YWHAH,PTGES3,FKBP4,PGR,ERRFI1,SRC,EGLN2,ESR2,PADI2,PHB1,DDX5,JAK2,TAF7,WBP2,RNF14,CALR,UBE3A,RBFOX2 |
| 4.392e-02 | -3.13 | TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | REACTOME pathways | R-HSA-6804114 | 19 | 10 | 10285 | 3229 |
EP300,CCNB1,TFDP2,GADD45A,E2F4,CDK1,SFN,BAX,PCNA,TP53 |
| 4.396e-02 | -3.12 | mineralocorticoid biosynthesis | BIOCYC pathways | HUMAN_PWY66-382 | 3 | 3 | 902 | 319 |
CYP11B1,CYP21A2,CYP11B2 |
| 4.396e-02 | -3.12 | mineralocorticoid biosynthesis | BIOCYC pathways | META_PWY66-382 | 3 | 3 | 902 | 319 |
CYP11B1,CYP21A2,CYP11B2 |
| 4.396e-02 | -3.12 | glucocorticoid biosynthesis | BIOCYC pathways | META_PWY66-381 | 3 | 3 | 902 | 319 |
CYP17A1,CYP21A2,CYP11B1 |
| 4.396e-02 | -3.12 | glucocorticoid biosynthesis | BIOCYC pathways | HUMAN_PWY66-381 | 3 | 3 | 902 | 319 |
CYP11B1,CYP21A2,CYP17A1 |
| 4.398e-02 | -3.12 | RNA transport | KEGG pathways | hsa03013 | 166 | 68 | 7161 | 2463 |
XPO1,EIF3E,THOC6,MAGOHB,EIF4A3,SEC13,PABPC1,MAGOH,SUMO2,EIF5B,EIF1AX,UBE2I,EIF4E2,NXT1,XPO5,NUP42,EIF3G,SMN1,CASC3,EIF4EBP3,THOC1,RPP14,EEF1A1,NCBP2,EIF4B,RPP21,ALYREF,EIF2B2,RPP25L,EIF2S2,PABPC5,SAP18,CYFIP2,XPOT,NUP50,EIF4A2,EIF1B,NUP107,FXR2,EIF4EBP2,SUMO3,PRMT5,THOC2,EIF3J,NUP35,SUMO1,UPF3B,PABPC1L,EIF3D,EIF2B3,EIF2S1,EIF4E,POP7,RPP25,PAIP1,GEMIN7,DDX39B,NXT2,PYM1,PHAX,GEMIN8,RAN,POP5,NUP153,NUP62,NUP37,EIF2B5,THOC3 |
| 4.398e-02 | -3.12 | RNA transport | KEGG pathways | ko03013 | 166 | 68 | 7161 | 2463 |
EIF2S2,RPP25L,SAP18,PABPC5,CYFIP2,EIF4A2,NUP50,XPOT,EIF1B,FXR2,NUP107,EIF4EBP2,SUMO3,PRMT5,THOC2,NUP35,EIF3J,SUMO1,UPF3B,PABPC1L,EIF3D,EIF2B3,EIF2S1,EIF4E,POP7,RPP25,PAIP1,GEMIN7,DDX39B,NXT2,PYM1,PHAX,RAN,GEMIN8,POP5,NUP153,NUP62,EIF2B5,NUP37,THOC3,EIF3E,XPO1,THOC6,MAGOHB,SEC13,EIF4A3,PABPC1,MAGOH,SUMO2,EIF5B,EIF1AX,UBE2I,EIF4E2,NXT1,XPO5,NUP42,CASC3,SMN1,EIF3G,EIF4EBP3,RPP14,THOC1,EEF1A1,NCBP2,EIF4B,ALYREF,RPP21,EIF2B2 |
| 4.399e-02 | -3.12 | TNS1 (tensin 1) | protein interactions | 7145 | 38 | 16 | 19454 | 5460 |
KLF10,GAB1,VIRMA,KIT,HDAC6,AR,PPP1CC,CSK,RAF1,BABAM1,MET,OSGEP,CAPN2,FRS3,LMNA,YWHAZ |
| 4.399e-02 | -3.12 | POFUT1 (protein O-fucosyltransferase 1) | protein interactions | 23509 | 38 | 16 | 19454 | 5460 |
H2AX,CCL3,MOV10,DPP4,TOP3B,FAM20C,RPA2,ACAA2,SEC61B,AKT2,LMBR1L,SOD1,RPA3,TMEM106B,FBXO32,ENO1 |
| 4.399e-02 | -3.12 | PARP4 (poly(ADP-ribose) polymerase family member 4) | protein interactions | 143 | 38 | 16 | 19454 | 5460 |
SMAD3,EGLN3,CDC5L,NUP35,VIRMA,FZR1,ARL6IP5,STAU1,SOX2,ZNF263,CDC23,COP1,SMDT1,SMAD4,MYO6,BRCA1 |
| 4.399e-02 | -3.12 | MPPED1 (metallophosphoesterase domain containing 1) | protein interactions | 758 | 38 | 16 | 19454 | 5460 |
TCP1,FBXW7,CCT7,PHKB,DISC1,MPPED2,SPP1,CCT2,ANXA7,UCKL1,UCK1,CIAO1,CCT5,UPRT,PHKA1,NR2F6 |
| 4.399e-02 | -3.12 | H2AC13 (H2A clustered histone 13) | protein interactions | 8329 | 38 | 16 | 19454 | 5460 |
COPS5,ELK4,RPL7A,HNRNPC,RPL26L1,RIT1,S100A8,PRKCB,RPLP2,PABPC1,VIRMA,CAND1,RPL35A,NEDD8,H3C1,RPL35 |
| 4.399e-02 | -3.12 | PIMREG (PICALM interacting mitotic regulator) | protein interactions | 54478 | 38 | 16 | 19454 | 5460 |
PRNP,SIAH1,S100B,RINT1,CSNK2B,TRIM27,TFCP2,TDRD7,PICALM,MTA2,SSX2IP,ARMC7,RAF1,BEND5,AGTRAP,CEP70 |
| 4.399e-02 | -3.12 | CCM2 (CCM2 scaffold protein) | protein interactions | 83605 | 38 | 16 | 19454 | 5460 |
SRPK2,RAD21,NRBF2,TWIST2,SMURF1,MAP3K3,STK26,SNIP1,DOK4,AP1S2,KRIT1,RHOB,TLNRD1,VSTM2L,RAB2A,CMSS1 |
| 4.399e-02 | -3.12 | EGLN2 (egl-9 family hypoxia inducible factor 2) | protein interactions | 112398 | 38 | 16 | 19454 | 5460 |
EGLN2,FBXW7,DYRK1A,RIGI,SRPK2,EGLN3,CDK6,MOB4,SPOP,PRKCA,CDK4,ATF4,CUL3,PRPF19,DYRK1B,SIAH2 |
| 4.399e-02 | -3.12 | TMED6 (transmembrane p24 trafficking protein 6) | protein interactions | 146456 | 38 | 16 | 19454 | 5460 |
C1QL1,ITGA6,ITGA2,LRP12,DNAJB9,SLC35A2,ST6GALNAC3,VEZT,NETO2,KCNJ8,DIPK1A,CGRRF1,SLC12A2,SMPD2,BTN2A2,POMT2 |
| 4.408e-02 | -3.12 | GIGYF2 (GRB10 interacting GYF protein 2) | protein interactions | 26058 | 244 | 81 | 19454 | 5460 |
EXOSC3,PNMA2,MTA2,RPS11,RBM12,KBTBD4,FBP1,TP53,KIF1C,WBP11,EXOSC8,LGR4,G3BP1,HUWE1,TRIM37,SMN1,RIGI,PABPC1,ZC3H7A,TESK2,TIAM1,YWHAB,MPHOSPH6,CAMSAP2,WWP2,CPEB1,YWHAH,XPO1,YWHAG,DIS3L,KCTD3,MIF,EGLN3,CD274,PHB1,EIF4E2,FBXO32,RFX5,MAGED2,PPARG,RPA2,CD46,DYRK2,ACACA,WDR83,WDR77,INPP5E,TANK,SIPA1L1,CDKN1A,MRPL12,KDM1A,FBXW7,STAU1,RPA3,SIRT7,RTKN,EXOSC4,RNF113A,C1D,RC3H2,YWHAZ,HSP90AA1,EXOSC1,UBE2H,MAPRE1,RBM7,OST4,GRB10,ANAPC15,MAP3K21,SNRPB,NDN,FBXO22,VIRMA,APEX1,OPTN,CCNF,RPS20,TRIM24,PHF21A |
| 4.417e-02 | -3.12 | PTPN23 (protein tyrosine phosphatase non-receptor type 23) | protein interactions | 25930 | 153 | 53 | 19454 | 5460 |
AP2A1,RIT1,UBE2H,LAMTOR1,BICD2,MYC,DHPS,SNX12,TRIM27,CCNF,SMAP2,ALG2,UBAP1,KLC2,P3H1,RPA2,PICALM,TOM1L2,NTPCR,SYNRG,PGRMC1,USP8,RAB5A,PSMA3,RAB9A,RPA3,INPPL1,NME2,TUBG1,CALR,VPS26A,STX6,CEP19,CAV1,MIF,TSG101,NRSN1,PBDC1,CHID1,GRAP2,HGS,RPN1,RAB4A,PPP2R1A,LGR4,TBK1,YTHDF2,RPS27A,KRAS,TOLLIP,TOM1,BAG2,ZYX |
| 4.417e-02 | -3.12 | regulation of blood circulation | biological process | GO:1903522 | 261 | 90 | 18204 | 5365 |
PDE4B,PIK3CG,LEP,BVES,SNTA1,HEY2,HSP90AA1,ADRB1,HTR2A,ADRA1A,SRC,ADORA1,ADORA3,APLN,TRPC1,KCNJ2,TMEM38B,TACR3,GNAO1,POPDC2,SCN1B,MIR1-1,MEF2A,TNNT2,CACNB2,MDM2,MIR21,HBEGF,GJC1,ATP1A3,JUP,TACR1,KCNMB2,KCND3,MIR30E,GSTO1,MIR208A,NOS1AP,ADM2,ZMPSTE24,CAV3,BMPR2,FKBP1B,UCN,HTR1A,EDNRA,CLIC2,CAV1,AGER,ASB3,GSTM2,KCND2,RGS2,RANGRF,TMIGD3,OXTR,AVPR1B,SLC1A1,ATP1A1,DBH,TGFB2,SCN3B,HRH2,STC1,TNF,SLC8A1,DES,ATP1A2,DLG1,TNNI3K,ATP1B1,KCNJ3,GJA1,CD38,DMPK,GHRL,SCN2B,PLN,MIR448,SUMO1,FGF13,SRI,ASIC2,KCNIP2,KCNJ8,GSK3A,CHGA,EHD3,MIR200C,ATP2B4 |
| 4.418e-02 | -3.12 | DNAH1 (dynein axonemal heavy chain 1) | protein interactions | 25981 | 8 | 5 | 19454 | 5460 |
H2BC9,MAP2K1,AGR2,H2AZ1,HNRNPL |
| 4.418e-02 | -3.12 | CXCR5 (C-X-C motif chemokine receptor 5) | protein interactions | 643 | 8 | 5 | 19454 | 5460 |
GNB3,CXCR4,GNA11,GNAI2,CXCL13 |
| 4.418e-02 | -3.12 | PENK (proenkephalin) | protein interactions | 5179 | 8 | 5 | 19454 | 5460 |
PDYN,ANAPC16,CDC23,ANAPC4,CDC26 |
| 4.418e-02 | -3.12 | Dnm1 (dynamin 1) | protein interactions | 140694 | 8 | 5 | 19454 | 5460 |
PIAS1,GABARAPL1,CLIC4,UBE2I,SUMO1 |
| 4.418e-02 | -3.12 | Emc1 (ER membrane protein complex subunit 1) | protein interactions | 230866 | 8 | 5 | 19454 | 5460 |
EMC10,EMC4,EMC8,EMC2,SRSF10 |
| 4.418e-02 | -3.12 | Bicdl1 (BICD family like cargo adaptor 1) | protein interactions | 75665 | 8 | 5 | 19454 | 5460 |
RAB6A,RAB11B,DYNC1I1,KIF1C,RAB6B |
| 4.418e-02 | -3.12 | SLC9A7 (solute carrier family 9 member A7) | protein interactions | 84679 | 8 | 5 | 19454 | 5460 |
HNRNPL,SCAMP5,GPR35,SCAMP2,RAB4A |
| 4.418e-02 | -3.12 | KMO (kynurenine 3-monooxygenase) | protein interactions | 8564 | 8 | 5 | 19454 | 5460 |
FBXO22,DISC1,OLFML3,FBXO7,GPHN |
| 4.418e-02 | -3.12 | SLC37A1 (solute carrier family 37 member 1) | protein interactions | 54020 | 8 | 5 | 19454 | 5460 |
GPR37,ADRB2,GPR35,DCAF4,HNRNPL |
| 4.418e-02 | -3.12 | STON1 (stonin 1) | protein interactions | 11037 | 8 | 5 | 19454 | 5460 |
VIRMA,SRPK2,ESR2,DDX39A,GSK3A |
| 4.418e-02 | -3.12 | Arrb2 (arrestin, beta 2) | protein interactions | 25388 | 8 | 5 | 19454 | 5460 |
ADRB2,TRAF6,SUFU,RAF1,AP2M1 |
| 4.418e-02 | -3.12 | FHOD3 (formin homology 2 domain containing 3) | protein interactions | 80206 | 8 | 5 | 19454 | 5460 |
CDC16,PIAS1,CDC23,ANAPC4,SQSTM1 |
| 4.418e-02 | -3.12 | CNPPD1 (cyclin Pas1/PHO80 domain containing 1) | protein interactions | 27013 | 8 | 5 | 19454 | 5460 |
CDK5,TNNC2,UBB,TOP3B,RSPH1 |
| 4.418e-02 | -3.12 | CHRNB3 (cholinergic receptor nicotinic beta 3 subunit) | protein interactions | 1142 | 8 | 5 | 19454 | 5460 |
HNRNPAB,SPPL3,NPW,CSK,GAMT |
| 4.418e-02 | -3.12 | APLN (apelin) | protein interactions | 8862 | 8 | 5 | 19454 | 5460 |
APLNR,PSMA3,MDFI,PLSCR4,TRIM63 |
| 4.418e-02 | -3.12 | FYB2 (FYN binding protein 2) | protein interactions | 199920 | 8 | 5 | 19454 | 5460 |
SKAP2,IRF2BP1,MLF1,MRPS9,TBCE |
| 4.418e-02 | -3.12 | Top3a (topoisomerase (DNA) III alpha) | protein interactions | 21975 | 8 | 5 | 19454 | 5460 |
RMI1,RMI2,SSBP1,RPA2,RPA3 |
| 4.418e-02 | -3.12 | PTGER1 (prostaglandin E receptor 1) | protein interactions | 5731 | 8 | 5 | 19454 | 5460 |
PTGES,PTGDS,PTGFR,SPPL3,ADRB2 |
| 4.418e-02 | -3.12 | ATP9B (ATPase phospholipid transporting 9B (putative)) | protein interactions | 374868 | 8 | 5 | 19454 | 5460 |
DVL2,HNRNPL,VIRMA,RIGI,PDE2A |
| 4.418e-02 | -3.12 | TDRD5 (tudor domain containing 5) | protein interactions | 163589 | 8 | 5 | 19454 | 5460 |
FABP5,METTL14,TUBA1B,EIF4B,UBB |
| 4.418e-02 | -3.12 | RASSF4 (Ras association domain family member 4) | protein interactions | 83937 | 8 | 5 | 19454 | 5460 |
DLG4,HMGB1,HGS,STK4,STK3 |
| 4.418e-02 | -3.12 | SVOP (SV2 related protein) | protein interactions | 55530 | 8 | 5 | 19454 | 5460 |
PSMD14,CCR2,FXYD6,CLK1,TAAR1 |
| 4.418e-02 | -3.12 | Dok1 (docking protein 1) | protein interactions | 13448 | 8 | 5 | 19454 | 5460 |
SMAD4,SMAD3,ACVR1B,NCK1,SMAD2 |
| 4.418e-02 | -3.12 | LY6E (lymphocyte antigen 6 family member E) | protein interactions | 4061 | 8 | 5 | 19454 | 5460 |
CD247,FCGR2B,RIGI,MFSD6,TMEM19 |
| 4.418e-02 | -3.12 | CASP5 (caspase 5) | protein interactions | 838 | 8 | 5 | 19454 | 5460 |
LACRT,CSK,MAX,CASP4,NLRP1 |
| 4.418e-02 | -3.12 | LY6G6D (lymphocyte antigen 6 family member G6D) | protein interactions | 58530 | 8 | 5 | 19454 | 5460 |
RNF139,SYVN1,FAM8A1,HSPA5,NCALD |
| 4.418e-02 | -3.12 | Melk (maternal embryonic leucine zipper kinase) | protein interactions | 17279 | 8 | 5 | 19454 | 5460 |
MDM2,TP53,ZNF622,SMAD3,TXN |
| 4.418e-02 | -3.12 | GIMAP2 (GTPase, IMAP family member 2) | protein interactions | 26157 | 8 | 5 | 19454 | 5460 |
TOR1B,ARFIP1,TRIM54,FBP1,STOM |
| 4.418e-02 | -3.12 | KCNK4 (potassium two pore domain channel subfamily K member 4) | protein interactions | 50801 | 8 | 5 | 19454 | 5460 |
ORMDL1,GOLGA5,NDFIP1,TMEM87A,CRYGB |
| 4.418e-02 | -3.12 | HTR1E (5-hydroxytryptamine receptor 1E) | protein interactions | 3354 | 8 | 5 | 19454 | 5460 |
PSMC3,HSPA8,ACTB,ATP5F1B,PSMC4 |
| 4.418e-02 | -3.12 | CEACAM3 (CEA cell adhesion molecule 3) | protein interactions | 1084 | 8 | 5 | 19454 | 5460 |
PMP22,CSNK1A1L,NINJ1,SRC,S100A8 |
| 4.418e-02 | -3.12 | TMEM144 (transmembrane protein 144) | protein interactions | 55314 | 8 | 5 | 19454 | 5460 |
TMEM237,DDX39A,TIMMDC1,ADRB2,HNRNPL |
| 4.418e-02 | -3.12 | Edem3 (ER degradation enhancer, mannosidase alpha-like 3) | protein interactions | 66967 | 8 | 5 | 19454 | 5460 |
DNAJB9,PRDX4,UFD1,SERPINA1,HSPA5 |
| 4.418e-02 | -3.12 | ULP1 (SUMO protease ULP1) | protein interactions | 856087 | 8 | 5 | 19454 | 5460 |
SUMO1,SUMO2,AGTRAP,TNF,CEP70 |
| 4.418e-02 | -3.12 | RAB41 (RAB41, member RAS oncogene family) | protein interactions | 347517 | 8 | 5 | 19454 | 5460 |
FEM1B,HSPB1,PPP5C,RAB6B,SPPL3 |
| 4.418e-02 | -3.12 | WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1) | protein interactions | 117166 | 8 | 5 | 19454 | 5460 |
TRAF7,APPBP2,CSNK2B,DDX39A,H1-5 |
| 4.418e-02 | -3.12 | TUSC1 (tumor suppressor candidate 1) | protein interactions | 286319 | 8 | 5 | 19454 | 5460 |
SMN1,EIF3D,PSMA3,GEMIN7,GGPS1 |
| 4.418e-02 | -3.12 | PITPNM2 (phosphatidylinositol transfer protein membrane associated 2) | protein interactions | 57605 | 8 | 5 | 19454 | 5460 |
TOP3B,VAPB,CPNE1,HNRNPL,XPO1 |
| 4.418e-02 | -3.12 | DISP3 (dispatched RND transporter family member 3) | protein interactions | 57540 | 8 | 5 | 19454 | 5460 |
RASGRP2,CA2,RPS14,SPPL3,CEACAM5 |
| 4.418e-02 | -3.12 | ZNF662 (zinc finger protein 662) | protein interactions | 389114 | 8 | 5 | 19454 | 5460 |
TRAF1,TRAF2,H1-3,RSPH1,MDFI |
| 4.418e-02 | -3.12 | RHD (Rh blood group D antigen) | protein interactions | 6007 | 8 | 5 | 19454 | 5460 |
TMEM237,TMEM14B,SCN3B,SSMEM1,BAZ1B |
| 4.418e-02 | -3.12 | PAQR4 (progestin and adipoQ receptor family member 4) | protein interactions | 124222 | 8 | 5 | 19454 | 5460 |
TIMM8A,FAM136A,CDK4,NFE2L2,KCNA2 |
| 4.418e-02 | -3.12 | LMBRD1 (LMBR1 domain containing 1) | protein interactions | 55788 | 8 | 5 | 19454 | 5460 |
VAMP3,RPN1,HNRNPC,STX12,CSGALNACT2 |
| 4.418e-02 | -3.12 | COX19 (cytochrome c oxidase assembly factor COX19) | protein interactions | 90639 | 8 | 5 | 19454 | 5460 |
COX11,PARL,SFXN1,CSK,AIFM1 |
| 4.418e-02 | -3.12 | MARCHF10 (membrane associated ring-CH-type finger 10) | protein interactions | 162333 | 8 | 5 | 19454 | 5460 |
NTAQ1,UNC45A,SRPK2,UBE2H,CTBP1 |
| 4.418e-02 | -3.12 | NMRK2 (nicotinamide riboside kinase 2) | protein interactions | 27231 | 8 | 5 | 19454 | 5460 |
LRP12,NEK2,SAT1,ST7,CDKN1A |
| 4.418e-02 | -3.12 | F2RL3 (F2R like thrombin or trypsin receptor 3) | protein interactions | 9002 | 8 | 5 | 19454 | 5460 |
F2,KRAS,FZR1,VIRMA,CSNK2A1 |
| 4.418e-02 | -3.12 | ZNF772 (zinc finger protein 772) | protein interactions | 400720 | 8 | 5 | 19454 | 5460 |
DDX39A,VIRMA,MOV10,CUL3,INSIG2 |
| 4.418e-02 | -3.12 | CRYBB2 (crystallin beta B2) | protein interactions | 1415 | 8 | 5 | 19454 | 5460 |
LMO4,HSPB1,CRYBB2,CRYAB,CRYBA1 |
| 4.418e-02 | -3.12 | RWDD2A (RWD domain containing 2A) | protein interactions | 112611 | 8 | 5 | 19454 | 5460 |
MCMBP,ARHGEF6,ATG7,PSMB1,GABARAP |
| 4.418e-02 | -3.12 | ZDHHC4 (zinc finger DHHC-type palmitoyltransferase 4) | protein interactions | 55146 | 8 | 5 | 19454 | 5460 |
CSK,SMAD3,ZFAND2B,CLDND1,MAVS |
| 4.418e-02 | -3.12 | ABTB3 (ankyrin repeat and BTB domain containing 3) | protein interactions | 121551 | 8 | 5 | 19454 | 5460 |
CUL3,TIAM1,CEP97,MAP1LC3B,MAP1LC3A |
| 4.418e-02 | -3.12 | PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5) | protein interactions | 23533 | 8 | 5 | 19454 | 5460 |
SDHB,GNB1,CFTR,PIK3CG,GNG2 |
| 4.418e-02 | -3.12 | RTP3 (receptor transporter protein 3) | protein interactions | 83597 | 8 | 5 | 19454 | 5460 |
MOV10,ELAVL2,CASC3,APOBEC3F,H1-1 |
| 4.418e-02 | -3.12 | KCNK9 (potassium two pore domain channel subfamily K member 9) | protein interactions | 51305 | 8 | 5 | 19454 | 5460 |
YWHAB,YWHAH,YWHAG,SFN,YWHAZ |
| 4.418e-02 | -3.12 | XRRA1 (X-ray radiation resistance associated 1) | protein interactions | 143570 | 8 | 5 | 19454 | 5460 |
HSPA8,DYRK2,KIAA0232,CSK,HSP90B1 |
| 4.418e-02 | -3.12 | Rnf111 (ring finger 111) | protein interactions | 93836 | 8 | 5 | 19454 | 5460 |
CSNK2A1,AP2M1,SMAD2,SUMO2,SMAD3 |
| 4.418e-02 | -3.12 | ZNF236 (zinc finger protein 236) | protein interactions | 7776 | 8 | 5 | 19454 | 5460 |
KRR1,TOP3B,HNRNPL,VIRMA,APEX1 |
| 4.418e-02 | -3.12 | HS6ST3 (heparan sulfate 6-O-sulfotransferase 3) | protein interactions | 266722 | 8 | 5 | 19454 | 5460 |
IDE,DDX39A,DEFB116,SPPL3,METTL14 |
| 4.423e-02 | -3.12 | FKBP_C | pfam domains | PF00254 | 15 | 8 | 17795 | 5224 |
FKBP2,AIP,FKBP14,FKBP10,FKBP1A,FKBP8,FKBP1B,FKBP4 |
| 4.423e-02 | -3.12 | Crystall | pfam domains | PF00030 | 15 | 8 | 17795 | 5224 |
CRYBB3,CRYBA2,CRYGA,CRYBA1,CRYGD,CRYBB2,CRYBA4,CRYGB |
| 4.423e-02 | -3.12 | glutamate receptor binding | molecular function | GO:0035254 | 47 | 20 | 18094 | 5411 |
PRNP,SYNDIG1,HOMER1,NETO1,PTPN4,NETO2,OPHN1,DLG3,IGSF11,GRIA1,CACNG3,HOMER3,DLG1,SDCBP,NSG1,CDK5R1,SQSTM1,FLOT1,NHERF1,DLG4 |
| 4.426e-02 | -3.12 | TADA3 (transcriptional adaptor 3) | protein interactions | 10474 | 137 | 48 | 19454 | 5460 |
TAF10,PSMC3,SF3B5,CBX3,CDK8,WDR37,IKZF5,CCDC134,TP53,RERE,STX11,SETD4,TAF9,KPNA1,CTNNB1,ENY2,ZNF7,SUPT7L,KLF3,RPA2,PPARG,EIF3J,KLF12,SUPT3H,ING5,CXXC1,SAP18,STAU1,SGF29,KDM1A,EP300,DR1,HSPA8,HCFC2,RPA3,MAGEH1,TADA1,AR,KANSL3,TXNRD2,TAF5L,MYC,ESR2,USP5,NR1I2,ACTB,SNRNP40,HEXIM2 |
| 4.426e-02 | -3.12 | ZNF460 (zinc finger protein 460) | protein interactions | 10794 | 137 | 48 | 19454 | 5460 |
MRPS9,OSBPL8,NOL4,ZCCHC10,MRPS35,MOV10,UTP25,MRPS18C,FGF12,TRIM63,TRIM37,TRIM26,MRPS33,H1-6,MRPS11,MRPS18B,SCPEP1,ZNF787,TOPORS,CHAMP1,ZMYM4,ASPM,IPO8,VIRMA,CBX5,RPF1,MRPS21,TRIM24,RNF187,ZMYM2,ZNF330,FBLN5,MRPS25,TEX19,NOA1,RNF40,TOMM40,ZNF687,CUL3,ZNF250,MRPS7,RBM22,NAP1L3,ZNF267,SDC2,ZMYM6,NOTCH2,ATG16L1 |
| 4.426e-02 | -3.12 | SPINT2 (serine peptidase inhibitor, Kunitz type 2) | protein interactions | 10653 | 137 | 48 | 19454 | 5460 |
TMUB1,CMTM6,EGFL7,LRP10,TEX264,RHOU,LEMD3,EPHX1,GOLGA5,SEC22A,ALG5,MAD2L2,CDC20,LRIF1,RHOJ,CTSB,SEC61B,CTU1,PRSS8,LRP12,SLC30A7,LMBR1L,ILK,DCAF4,BAG3,ARL6IP6,CNTNAP1,CUL3,RETSAT,SACM1L,ACVR1B,SLC39A3,KLHL26,RPS7,ARFGEF1,NOP9,WDR44,RHOH,OCRL,SLC39A10,OSBPL8,NUS1,TUBG1,MZT2B,KLHL22,DHRS7,MOV10,DPP4 |
| 4.427e-02 | -3.12 | response to tumor necrosis factor | biological process | GO:0034612 | 183 | 65 | 18204 | 5365 |
TP53,AKAP12,RRAGA,TNF,CXCL8,CCL5,ADIPOQ,FOXP1,NFKBIA,EDA2R,MIR142,ZFAND6,RPS3,IL18BP,BIRC2,MIR34A,CAMP,SFRP1,TRAF2,CTSK,CX3CR1,HYAL2,TXNDC17,TRAF3IP2,CRHBP,TRAF1,TRIM32,CD40,DHX9,INPP5K,AKT1,CCL3,KCNJ11,TANK,TNFSF18,PYCARD,CD58,NKX3-1,IKBKB,ACTN4,STAT1,TMSB4X,CCL2,CHI3L1,JAK2,NFE2L2,FOS,TNFRSF14,TUBA1A,KRT8,NFKB1,ILK,PID1,MIR31,CYP1B1,BRCA1,TRAF6,CD14,FAS,TNFRSF1B,PCK2,FABP4,IGBP1,TIFA,CLDN1 |
| 4.431e-02 | -3.12 | SLC30A2 (solute carrier family 30 member 2) | protein interactions | 7780 | 99 | 36 | 19454 | 5460 |
CTSA,LMNA,ADCY3,DCAKD,NRM,SEC22A,RER1,SLC7A1,TMEM60,ABCC5,TMX2,LTA,CD40,EMP3,HSPA8,TAS2R5,ESYT1,TM4SF18,FXYD6,AQP2,CD52,GJB2,FAM174A,OPRM1,CYB561D2,SLC38A7,CREB3,CTSD,ATG9A,TMEM107,SPPL3,F11R,CD99L2,SLC7A8,SELL,PLPPR1 |
| 4.433e-02 | -3.12 | granulocytic_sarcoma | COSMIC cancer mutations | granulocytic_sarcoma | 26 | 12 | 16828 | 4835 |
KRAS,HRAS,IDH1,JAK1,CBL,KIT,MET,AKT1,PTPN11,JAK2,IDH2,FBXW7 |
| 4.433e-02 | -3.12 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-granulocytic_sarcoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-granulocytic_sarcoma | 26 | 12 | 16828 | 4835 |
KIT,MET,FBXW7,IDH2,AKT1,PTPN11,JAK2,KRAS,HRAS,CBL,IDH1,JAK1 |
| 4.434e-02 | -3.12 | Direct p53 effectors | Pathway Interaction DB | p53downstreampathway | 132 | 56 | 2226 | 782 |
CX3CL1,BAK1,PCBP4,PYCARD,BTG2,PMAIP1,MET,SCN3B,DGCR8,SPP1,SFN,EPHA2,RPS27L,CDKN1A,DKK1,SH2D1A,RCHY1,PTEN,RB1,SNAI2,CSE1L,DDIT4,CTSD,VDR,CREBBP,JUN,COP1,TP53,IGFBP3,SP1,FAS,MCL1,PRKAB1,BCL6,DDX5,CCNB1,MDM2,NFYA,DUSP1,RGCC,ATF3,TAF9,RNF144B,TP53I3,BCL2A1,GADD45A,BAX,EP300,PCNA,NFYB,BNIP3L,GPX1,TP53INP1,PML,DROSHA,CAV1 |
| 4.435e-02 | -3.12 | ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2) | protein interactions | 157570 | 68 | 26 | 19454 | 5460 |
PSENEN,KDM1A,RBBP7,H3C1,SLC31A1,MCM6,ADD2,PCNA,PICK1,CHMP4C,MACROH2A2,H2AJ,RAF1,MATR3,RPGRIP1L,MACROH2A1,PHF21A,HP1BP3,H1-10,UQCR11,MOV10,NDC80,ANAPC15,MCM3,SUV39H1,MCM4 |
| 4.435e-02 | -3.12 | DPY19L1 (dpy-19 like C-mannosyltransferase 1) | protein interactions | 23333 | 68 | 26 | 19454 | 5460 |
OTULINL,SEC62,ISG15,RAF1,TP53,CRELD1,CHRNB2,CYB5B,SEMA7A,RPA2,EZH2,RPN1,GP9,LDLRAD4,VIPR1,RPA3,NEK9,HS2ST1,HSCB,VDAC1,SCN3B,UPK1A,SLC1A1,CD79B,STUM,APLNR |
| 4.435e-02 | -3.12 | NDUFAF7 (NADH:ubiquinone oxidoreductase complex assembly factor 7) | protein interactions | 55471 | 68 | 26 | 19454 | 5460 |
HSPD1,COX8A,GPSM3,MRPS18B,HINT2,RASL10B,NDUFS2,ABHD10,IMMP2L,OGDHL,FNTB,FEM1A,PDHA1,METTL2A,DMAP1,SSBP1,TRIM44,ZMAT2,GATD3,DNASE1L1,YBEY,ST3GAL5,MALSU1,NAA11,MRM2,MTRF1 |
| 4.441e-02 | -3.11 | FoxO family signaling | Pathway Interaction DB | foxopathway | 48 | 23 | 2226 | 782 |
IKBKB,CCNB1,BCL6,RAN,EP300,MAPK10,SOD2,GADD45A,FBXO32,AKT1,CSNK1E,YWHAZ,CSNK1G3,YWHAB,CTNNB1,YWHAG,CDKN1B,FASLG,SFN,CSNK1A1,CREBBP,XPO1,YWHAH |
| 4.442e-02 | -3.11 | Golgi-associated vesicle membrane | cellular component | GO:0030660 | 57 | 23 | 19108 | 5553 |
TMEM199,CFTR,NCALD,KDELR2,COPE,DIPK2A,AFTPH,SPPL3,KDELR1,AP1G2,TMED3,ARCN1,GJA1,ZDHHC17,CLBA1,COPZ2,TMED7,AP2A1,AP1M1,AP1S2,ITM2B,GPR89A,SYNRG |
| 4.446e-02 | -3.11 | TRIM73 (tripartite motif containing 73) | protein interactions | 375593 | 21 | 10 | 19454 | 5460 |
TTC23,DDX39A,NTAQ1,GNG3,DDIT4L,C9orf72,PNMA1,HGS,HSP90AA1,OIP5 |
| 4.446e-02 | -3.11 | AGER (advanced glycosylation end-product specific receptor) | protein interactions | 177 | 21 | 10 | 19454 | 5460 |
KRAS,TTR,HMGB1,FBXW7,FGFR1,CMTM7,NRP1,CREB3,S100B,SEC61B |
| 4.446e-02 | -3.11 | LPIN2 (lipin 2) | protein interactions | 9663 | 21 | 10 | 19454 | 5460 |
COP1,DCAF11,DYRK1A,VIRMA,SMAD4,YWHAZ,FBXW11,DCAF4,FNTB,DYRK1B |
| 4.446e-02 | -3.11 | ZNF431 (zinc finger protein 431) | protein interactions | 170959 | 21 | 10 | 19454 | 5460 |
POLR2F,ICAM3,CDKN1A,NOTCH2,RPL27A,SMN1,VIRMA,ANXA7,RPL13A,TRIM63 |
| 4.446e-02 | -3.11 | SGSM3 (small G protein signaling modulator 3) | protein interactions | 27352 | 21 | 10 | 19454 | 5460 |
RAB5A,GJA1,RAB5C,CHRM3,RAB39B,FMO3,RPL35,CD226,NF2,NPTN |
| 4.446e-02 | -3.11 | SMPD3 (sphingomyelin phosphodiesterase 3) | protein interactions | 55512 | 21 | 10 | 19454 | 5460 |
STOM,GABPA,ENDOD1,STX17,PPP3CA,CAV1,CCR1,ST7,DDX39A,EED |
| 4.446e-02 | -3.11 | FAM25G (family with sequence similarity 25 member G) | protein interactions | 100133093 | 21 | 10 | 19454 | 5460 |
ARMCX3,SNX1,COX16,PPIC,KRAS,RIT1,MIEF1,S100A6,LCN1,PPIF |
| 4.446e-02 | -3.11 | MATN4 (matrilin 4) | protein interactions | 8785 | 21 | 10 | 19454 | 5460 |
ARG2,GORASP2,BCS1L,ZMYM2,NTAQ1,VIPAS39,SDCBP,HSPA5,ENKD1,HAX1 |
| 4.446e-02 | -3.11 | UROS (uroporphyrinogen III synthase) | protein interactions | 7390 | 21 | 10 | 19454 | 5460 |
ATG7,COPS5,EED,CTU1,LDLR,PNPLA4,TP53,BOLA1,TCEAL1,ATG3 |
| 4.446e-02 | -3.11 | GLIS3 (GLIS family zinc finger 3) | protein interactions | 169792 | 21 | 10 | 19454 | 5460 |
BAG3,SOX2,DDX39A,PRMT5,TSG101,ENO1,SUFU,RIGI,NUP35,TRAF1 |
| 4.446e-02 | -3.11 | COL11A1 (collagen type XI alpha 1 chain) | protein interactions | 1301 | 21 | 10 | 19454 | 5460 |
PYCR1,PYCR2,RAF1,DDR1,CSK,FBXL19,SOX2,PRNP,ITGAV,PDE2A |
| 4.446e-02 | -3.11 | KCND2 (potassium voltage-gated channel subfamily D member 2) | protein interactions | 3751 | 21 | 10 | 19454 | 5460 |
BAG3,HSPA8,DLG4,STUB1,DPP10,GNB4,KCNIP2,KCTD17,KCNIP3,TLR3 |
| 4.446e-02 | -3.11 | IGKV4-1 (immunoglobulin kappa variable 4-1) | protein interactions | 28908 | 21 | 10 | 19454 | 5460 |
BTF3,CDK7,DDRGK1,MYC,CUL2,HSPA5,UBE2H,UFL1,SNRNP70,FBXO22 |
| 4.446e-02 | -3.11 | DCT (dopachrome tautomerase) | protein interactions | 1638 | 21 | 10 | 19454 | 5460 |
HYAL2,LGR4,ALG11,ITM2B,RAF1,PRKAB1,PLP1,EDEM2,TMEM30A,SEMA4C |
| 4.446e-02 | -3.11 | SPRR2A (small proline rich protein 2A) | protein interactions | 6700 | 21 | 10 | 19454 | 5460 |
YES1,PEX13,UBE2H,SRC,CCR1,CTTN,DLG4,CD274,AKT2,ITK |
| 4.446e-02 | -3.11 | GPR61 (G protein-coupled receptor 61) | protein interactions | 83873 | 21 | 10 | 19454 | 5460 |
PMP22,SCN3B,PLP1,EMP3,TMEM147,CTXN3,ATP6V0B,ARL6IP6,FCER1G,CLDND1 |
| 4.453e-02 | -3.11 | FGF10 (fibroblast growth factor 10) | protein interactions | 2255 | 13 | 7 | 19454 | 5460 |
FGFR1,RPL26L1,H1-1,TP53,FBXO7,SREK1IP1,THAP1 |
| 4.453e-02 | -3.11 | SGMS2 (sphingomyelin synthase 2) | protein interactions | 166929 | 13 | 7 | 19454 | 5460 |
CTSA,CX3CL1,PTAR1,LMNA,VAMP1,VIRMA,TMPO |
| 4.453e-02 | -3.11 | CXCL13 (C-X-C motif chemokine ligand 13) | protein interactions | 10563 | 13 | 7 | 19454 | 5460 |
CDKN1A,CCL28,CCL4L1,EEF1G,CCL19,CCL21,CXCR3 |
| 4.453e-02 | -3.11 | REXO1 (RNA exonuclease 1 homolog) | protein interactions | 57455 | 13 | 7 | 19454 | 5460 |
UBA52,TOP3B,RLIM,TCEA1,AP2M1,PAFAH1B2,SSRP1 |
| 4.453e-02 | -3.11 | NNMT (nicotinamide N-methyltransferase) | protein interactions | 4837 | 13 | 7 | 19454 | 5460 |
CRYZ,HSPA8,CDC73,PML,GLOD4,ATG16L1,ADK |
| 4.453e-02 | -3.11 | GABPB2 (GA binding protein transcription factor subunit beta 2) | protein interactions | 126626 | 13 | 7 | 19454 | 5460 |
GABPA,KDM1A,SNRPB2,ESR2,VAC14,ZDHHC17,GORASP2 |
| 4.453e-02 | -3.11 | Srsf9 (serine and arginine-rich splicing factor 9) | protein interactions | 108014 | 13 | 7 | 19454 | 5460 |
RBM7,H2AX,CLK1,PRPF31,RPL9,PNO1,PPIL3 |
| 4.453e-02 | -3.11 | KCNQ4 (potassium voltage-gated channel subfamily Q member 4) | protein interactions | 9132 | 13 | 7 | 19454 | 5460 |
HSP90AA1,HSPA8,HCRT,CYP4F12,HMGA1,STUB1,HSP90B1 |
| 4.453e-02 | -3.11 | IL17RD (interleukin 17 receptor D) | protein interactions | 54756 | 13 | 7 | 19454 | 5460 |
VIRMA,RIGI,TOP3B,CSK,RRN3,FBXW11,FGFR1 |
| 4.453e-02 | -3.11 | PGM2L1 (phosphoglucomutase 2 like 1) | protein interactions | 283209 | 13 | 7 | 19454 | 5460 |
ARFIP1,PITPNB,NPSR1,HSPE1,SKA3,COTL1,OAZ1 |
| 4.453e-02 | -3.11 | CFAP300 (cilia and flagella associated protein 300) | protein interactions | 85016 | 13 | 7 | 19454 | 5460 |
TAB1,FBXO7,COPS5,DDX39A,ACTA2,CUL2,CUL3 |
| 4.453e-02 | -3.11 | ATG4D (autophagy related 4D cysteine peptidase) | protein interactions | 84971 | 13 | 7 | 19454 | 5460 |
ATG4C,GABARAP,RIGI,MAP1LC3B,GABARAPL1,P4HA2,GABARAPL2 |
| 4.453e-02 | -3.11 | SAC3D1 (SAC3 domain containing 1) | protein interactions | 29901 | 13 | 7 | 19454 | 5460 |
GPIHBP1,TTC4,SEM1,DCUN1D5,VPS26A,TOP3B,DDX39B |
| 4.453e-02 | -3.11 | KCNJ3 (potassium inwardly rectifying channel subfamily J member 3) | protein interactions | 3760 | 13 | 7 | 19454 | 5460 |
ADRB2,KCNJ3,HNRNPL,SPPL3,GABBR1,GNB1,DDX39A |
| 4.453e-02 | -3.11 | SHROOM2 (shroom family member 2) | protein interactions | 357 | 13 | 7 | 19454 | 5460 |
ATG16L1,YWHAG,DDX39A,MRPL12,HNRNPL,VIRMA,ESR2 |
| 4.453e-02 | -3.11 | ZNF718 (zinc finger protein 718) | protein interactions | 255403 | 13 | 7 | 19454 | 5460 |
SAV1,H2BC9,TRIM24,HNRNPL,OGDHL,CBX5,STK3 |
| 4.453e-02 | -3.11 | FAM117A (family with sequence similarity 117 member A) | protein interactions | 81558 | 13 | 7 | 19454 | 5460 |
YWHAB,DYRK1A,DYNLL1,YWHAG,YWHAH,PICK1,DYRK1B |
| 4.453e-02 | -3.11 | C10orf67 (chromosome 10 open reading frame 67) | protein interactions | 256815 | 13 | 7 | 19454 | 5460 |
TNF,TMEM19,TMEM208,SEC22A,ORMDL3,TMEM14B,BCL2L1 |
| 4.453e-02 | -3.11 | OGN (osteoglycin) | protein interactions | 4969 | 13 | 7 | 19454 | 5460 |
ASB7,HSP90B1,CNPY3,CSK,NPTX1,TP53,TANK |
| 4.453e-02 | -3.11 | IL23R (interleukin 23 receptor) | protein interactions | 149233 | 13 | 7 | 19454 | 5460 |
C1D,AR,JAK2,PDF,PRKCA,ACTB,IL23A |
| 4.453e-02 | -3.11 | MKX (mohawk homeobox) | protein interactions | 283078 | 13 | 7 | 19454 | 5460 |
CNP,VIRMA,GTF2A1,HSP90AA1,HSH2D,GTF2B,SIN3A |
| 4.453e-02 | -3.11 | PCAT1 (prostate cancer associated transcript 1) | protein interactions | 100750225 | 13 | 7 | 19454 | 5460 |
FAF2,PCCB,EP300,TUFM,PDIA3,AAMP,GJA10 |
| 4.453e-02 | -3.11 | TRIM16L (tripartite motif containing 16 like (pseudogene)) | protein interactions | 147166 | 13 | 7 | 19454 | 5460 |
COMMD2,CFTR,HSPA8,DDX39A,COMMD3,CCDC22,CD46 |
| 4.453e-02 | -3.11 | NCAN (neurocan) | protein interactions | 1463 | 13 | 7 | 19454 | 5460 |
CNTN2,HMGB1,L1CAM,PTN,MNAT1,TNR,CMTR1 |
| 4.453e-02 | -3.11 | CSF2RA (colony stimulating factor 2 receptor subunit alpha) | protein interactions | 1438 | 13 | 7 | 19454 | 5460 |
FATE1,PIK3R1,RPSA,CSF2,KIT,IKBKB,SDC2 |
| 4.453e-02 | -3.11 | IL2 (interleukin 2) | protein interactions | 3558 | 13 | 7 | 19454 | 5460 |
SHC1,IL2,IL2RB,S100A6,IL2RG,CFTR,IL2RA |
| 4.453e-02 | -3.11 | LRRC14 (leucine rich repeat containing 14) | protein interactions | 9684 | 13 | 7 | 19454 | 5460 |
COPS4,ELOC,COPS5,PRNP,CUL2,IKBKB,TOP3B |
| 4.453e-02 | -3.11 | TMPRSS11A (transmembrane serine protease 11A) | protein interactions | 339967 | 13 | 7 | 19454 | 5460 |
CYRIB,SRPK2,TMEM11,ZBTB17,RAB6B,TMEM70,SERPINB6 |
| 4.453e-02 | -3.11 | SAMD7 (sterile alpha motif domain containing 7) | protein interactions | 344658 | 13 | 7 | 19454 | 5460 |
OIP5,FAM168B,TP53,KRTAP3-1,CSK,FBP1,KLHL15 |
| 4.458e-02 | -3.11 | transcription elongation by RNA polymerase II | biological process | GO:0006368 | 42 | 18 | 18204 | 5365 |
GTF2F2,EPOP,POLR2I,USP15,EAF2,GTF2F1,ELOF1,SUPT4H1,ADRM1,CDC73,TCEA2,SUPT5H,ENY2,CDK9,ERCC3,TCEA1,SKIC8,SART3 |
| 4.458e-02 | -3.11 | positive regulation of immunoglobulin mediated immune response | biological process | GO:0002891 | 42 | 18 | 18204 | 5365 |
SHLD1,IL2,CD28,STAT6,KMT5B,LTA,CD226,TFRC,EXOSC3,FCGR1A,NECTIN2,HMCES,TNF,MAD2L2,TNFSF13,CD40,XCL1,IL4 |
| 4.458e-02 | -3.11 | protein monoubiquitination | biological process | GO:0006513 | 42 | 18 | 18204 | 5365 |
RNF152,TOPORS,RNF10,SKP1,HUWE1,TRIM21,UBE2D3,RNF126,MSL2,KLHL22,TRIM37,KLHL12,STUB1,UBE2W,CUL3,DTL,ZC4H2,CBL |
| 4.458e-02 | -3.11 | positive regulation of B cell mediated immunity | biological process | GO:0002714 | 42 | 18 | 18204 | 5365 |
CD28,IL2,SHLD1,STAT6,KMT5B,LTA,CD226,EXOSC3,TFRC,FCGR1A,NECTIN2,HMCES,TNF,MAD2L2,TNFSF13,CD40,XCL1,IL4 |
| 4.461e-02 | -3.11 | Viral carcinogenesis | KEGG pathways | ko05203 | 201 | 81 | 7161 | 2463 |
H2BC1,GTF2E2,UBE3A,PIK3R2,CDC42,ACTN4,KRAS,IRF9,PIK3R1,CCNA2,CCND1,CCR4,VAC14,MDM2,CREBBP,TRAF2,CREB3L4,PSMC1,TRAF1,STAT5A,EGR2,CDC20,CDKN1A,CREB3,CDK1,JUN,LTBR,CDK4,CCR5,PIK3CA,BAD,CCND3,BAX,HDAC3,YWHAG,GTF2A2,H2BC12,PIK3R3,YWHAB,H2BW1,IRF7,HDAC6,YWHAZ,TP53,H2BC11,SYK,H2BC14,GTF2A1,HDAC5,CREB1,H2BC9,GTF2H4,CDK6,CCR3,RB1,PRKACB,RANBP1,HDAC11,ATF4,JAK1,EP300,IL6ST,EIF2AK2,SRC,HRAS,GTF2E1,NFKBIA,RBPJ,IRF3,GTF2B,BAK1,NFKB1,PMAIP1,HNRNPK,H2BC17,MRPS18B,GTF2H2,CDKN1B,DLG1,POLB,YWHAH |
| 4.461e-02 | -3.11 | Viral carcinogenesis | KEGG pathways | hsa05203 | 201 | 81 | 7161 | 2463 |
BAD,PIK3CA,CCND3,BAX,HDAC3,H2BC12,YWHAB,PIK3R3,GTF2A2,YWHAG,H2BW1,IRF7,CDC20,STAT5A,EGR2,CDK1,CDKN1A,CREB3,LTBR,JUN,CCR5,CDK4,VAC14,CCNA2,CCR4,CCND1,CREBBP,TRAF2,MDM2,CREB3L4,PSMC1,TRAF1,UBE3A,H2BC1,GTF2E2,CDC42,PIK3R2,ACTN4,KRAS,IRF9,PIK3R1,CDKN1B,DLG1,POLB,YWHAH,PMAIP1,BAK1,GTF2B,NFKB1,HNRNPK,H2BC17,MRPS18B,GTF2H2,PRKACB,CCR3,RB1,JAK1,RANBP1,HDAC11,ATF4,SRC,HRAS,EP300,EIF2AK2,IL6ST,NFKBIA,GTF2E1,RBPJ,IRF3,HDAC6,TP53,YWHAZ,H2BC11,CREB1,H2BC9,H2BC14,SYK,HDAC5,GTF2A1,CDK6,GTF2H4 |
| 4.463e-02 | -3.11 | HECTc | smart domains | SM00119 | 28 | 12 | 9717 | 2575 |
G2E3,AREL1,UBE3A,HECTD1,HERC3,HECTD3,HUWE1,WWP2,WWP1,HERC4,SMURF1,HECW1 |
| 4.465e-02 | -3.11 | regulation of biological process involved in symbiotic interaction | biological process | GO:0043903 | 65 | 26 | 18204 | 5365 |
TRIM5,NECTIN2,CD4,IFNA2,PPARA,TRIM21,TRIM26,MIR130A,SNX3,HS3ST5,CH25H,ITGAV,TRIM34,TRIM10,TRIM22,HMGB1,TRIM6,TRIM8,TRIM62,MIR141,FURIN,TRIM68,EXOC2,CXCL8,TRIM11,CAV1 |
| 4.465e-02 | -3.11 | Intra-Golgi traffic | REACTOME pathways | R-HSA-6811438 | 45 | 20 | 10285 | 3229 |
SNAP29,CYTH1,NAPG,STX16,GOLGA5,COG1,CYTH2,STX5,STX6,RAB33B,BET1L,YKT6,GOSR1,ARF1,RGP1,CYTH4,MAN1A2,GOSR2,NAPA,RAB30 |
| 4.469e-02 | -3.11 | - | gene3d domains | 3.10.50.40 | 18 | 9 | 14470 | 4137 |
FKBP1A,FKBP2,FKBP8,FKBP10,AIPL1,AIP,FKBP1B,FKBP4,FKBP14 |
| 4.473e-02 | -3.11 | myeloid cell homeostasis | biological process | GO:0002262 | 140 | 51 | 18204 | 5365 |
TRIM10,KLF1,TSPO2,MAEA,G6PD,KIT,CEBPG,CHMP5,RACGAP1,UFL1,RPS24,LIPA,ATP5IF1,CCR2,BPGM,SOD1,INHA,LYAR,HCLS1,EPO,JAK2,SLC11A2,SFXN1,BAP1,CDK5RAP3,NCSTN,VEGFA,RB1,NCAPG2,SLC25A5,IREB2,PRDX1,HMGB1,RAC2,BCL6,FOXP3,MPIG6B,SMAD5,PKNOX1,HDAC6,HSCB,PDE4B,SLC48A1,RPS14,RPS17,TRAF3IP2,BAX,RHAG,IL6,BAK1,TMOD3 |
| 4.476e-02 | -3.11 | human chr11q13.4 | chromosome location | human chr11q13.4 | 77 | 24 | 26134 | 5823 |
RNF121,FAM168A,IL18BP,MIR139,UCP2,CLPB,LIPT2,OR2AT4,COA4,FCHSD2,INPPL1,RPS3,LRTOMT,FOLR1,PDE2A,SPCS2,PAAF1,PGM2L1,RAB6A,PPME1,LAMTOR1,ANAPC15,FOLR2,SLCO2B1 |
| 4.476e-02 | -3.11 | VPS35L (VPS35 endosomal protein sorting factor like) | protein interactions | 57020 | 41 | 17 | 19454 | 5460 |
COMMD8,COMMD3,COMMD5,ATG7,HDAC11,CCDC22,PNMA2,STMN2,TSNAX,CNKSR3,COMMD2,VPS26C,COMMD6,HNRNPK,HNRNPL,DCUN1D1,VIRMA |
| 4.476e-02 | -3.11 | KCNJ2 (potassium inwardly rectifying channel subfamily J member 2) | protein interactions | 3759 | 41 | 17 | 19454 | 5460 |
TRAK2,DLG1,DLG4,HMGB1,STK38,ROCK2,SEC22A,CAV3,KCNJ8,NONO,KCNJ11,DLG3,EIF4B,USP15,CASK,KCNJ2,SDCBP |
| 4.476e-02 | -3.11 | SEC61G (SEC61 translocon subunit gamma) | protein interactions | 23480 | 41 | 17 | 19454 | 5460 |
RPS16,KRAS,ESR2,RIGI,RBM42,RPA3,PSPC1,SEC61B,SEC61A1,CSNK2B,SFTPC,RPA2,MAPRE1,DRG1,CREB3,CCDC47,DDX39A |
| 4.476e-02 | -3.11 | SYDE2 (synapse defective Rho GTPase homolog 2) | protein interactions | 84144 | 41 | 17 | 19454 | 5460 |
PALM2AKAP2,PPP1R12A,S100B,DLAT,ATP5IF1,KPNA2,SUMO3,VIRMA,POLR2B,TPM3,YWHAH,CFL1,YWHAG,PPP2R1A,ACTR2,YWHAZ,YWHAB |
| 4.476e-02 | -3.11 | SERPINA5 (serpin family A member 5) | protein interactions | 5104 | 41 | 17 | 19454 | 5460 |
MSMO1,KLK3,THBD,MIA2,BCAP29,SEMG2,HECTD3,F10,RCHY1,SERPINA5,FURIN,CBL,SEC22B,F2,EPS8,H1-5,RAF1 |
| 4.476e-02 | -3.11 | KLHL3 (kelch like family member 3) | protein interactions | 26249 | 41 | 17 | 19454 | 5460 |
UBE2D3,SYT2,GNAO1,CLDN8,SQSTM1,SYNCRIP,ACTA2,KLHL26,PPP3CA,UBE2H,KLHL12,NUDCD3,SOX9,TNPO2,KLHL3,AKT1,CUL3 |
| 4.476e-02 | -3.11 | CCDC43 (coiled-coil domain containing 43) | protein interactions | 124808 | 41 | 17 | 19454 | 5460 |
ATP5PB,ATG16L1,PPP2R1A,SMAD4,DOK4,SCNM1,RAN,GSK3A,ANAPC16,EWSR1,RPS20,ADRM1,MED17,SCML1,MRPS18C,UNC45A,ZBTB2 |
| 4.477e-02 | -3.11 | COMT (catechol-O-methyltransferase) | protein interactions | 1312 | 166 | 57 | 19454 | 5460 |
MFSD14B,COL1A2,TMEM100,RAB2A,MYC,VAMP5,CUL3,RAB14,REEP4,TXNDC12,IDE,SLC7A8,RABIF,VAMP3,AP1G2,ODR4,RPA2,USP6NL,CDC42,UQCRC1,SLC48A1,LITAF,GTF2I,SLC7A1,FXR2,CLDND1,PYGB,RGS2,RPA3,BAP1,COX17,RAB5A,CRBN,POR,ESYT1,PRNP,PEG10,CDK9,TLCD4,ATP6V1A,SLC35F1,CHMP4C,AP1S2,TMEM14B,RAF1,DCAKD,CCDC47,SELENOK,PGAP2,TMEM205,GJB1,AP1M1,TMEM50A,RIGI,PLPP6,RDH11,NSDHL |
| 4.478e-02 | -3.11 | KIR2DL3 (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3) | protein interactions | 3804 | 65 | 25 | 19454 | 5460 |
RNF152,PLN,ADGRE2,BTN2A2,SLC38A7,VAMP5,ANKRD46,THBD,CXCL9,TMEM97,FUNDC2,AIG1,CDIPT,TRAF3IP3,CYBC1,FAM3C,CYB5B,ATP6V0E1,INSIG2,AGTRAP,SEC22B,NRM,NSG1,JAGN1,TMEM243 |
| 4.478e-02 | -3.11 | LPAR3 (lysophosphatidic acid receptor 3) | protein interactions | 23566 | 65 | 25 | 19454 | 5460 |
CLDN9,RETREG3,ELOVL4,TMEM237,GNAI2,HNRNPL,MGST3,FNDC9,TMEM41A,NDUFAF2,OPRM1,SCN3B,CYB561,TMEM70,KCNC1,CYBRD1,JAGN1,LEPROTL1,CLEC12B,SGMS2,ASZ1,TMEM14B,TMEM31,LMNA,RELL2 |
| 4.479e-02 | -3.11 | BCL7A (BAF chromatin remodeling complex subunit BCL7A) | protein interactions | 605 | 118 | 42 | 19454 | 5460 |
SMAD2,BRD3,LHX2,H2AC4,IRF1,SMARCE1,BCL7C,ACTL6B,AR,HNF1B,MYC,CAP2,CIAO1,INO80E,IRF4,CUL3,CBX5,CD151,RPS12,BRD9,PAX9,SMARCB1,KLF4,RPRD1B,PPARG,EGR2,SOX2,ACTL6A,TOP3B,E2F4,SS18,PAX6,EMC8,NMRAL1,APPBP2,MYO1B,INO80C,S100B,KLHL23,BCL7B,SMARCD3,FOS |
| 4.484e-02 | -3.10 | Chromosome Maintenance | REACTOME pathways | R-HSA-73886 | 109 | 43 | 10285 | 3229 |
H2AC6,H2BC1,POLE3,H2AC14,TERT,PCNA,RFC4,PRIM2,H2BC9,RFC5,RPA3,CENPM,NHP2,CENPL,RFC3,H2BC12,H2AC4,WRAP53,DKC1,CENPP,H2AJ,RUVBL2,FEN1,H2BC17,H2AX,CENPW,RPA2,H2BC14,H2BC11,RBBP4,POLD2,OIP5,SMARCA5,RBBP7,H2AZ2,H2AB1,POLD4,H2AC7,RFC2,POLA2,RUVBL1,H2AZ1,POLE4 |
| 4.496e-02 | -3.10 | T-Cell antigen Receptor (TCR) Signaling Pathway | WikiPathways | WP69 | 91 | 41 | 5310 | 1910 |
SHC1,CRKL,BCL10,IKBKB,PIK3R1,TRAF6,LHB,NCK1,IL15RA,CDC42,PRKCQ,ITK,CD247,CD83,OPRM1,CCR5,IL6,CREB1,MAP2K1,AKT1,FOS,CD3G,PTPN11,CD4,TNFRSF9,IRF4,NFKB1,FAS,IL1A,MAP3K14,JUN,IL1B,NFKBIA,LCP2,HRAS,RAF1,ICOS,CD28,GRAP2,PIK3R2,CBL |
| 4.508e-02 | -3.10 | Ponatinib Inhibition of BCR-ABL | SMPDB pathways | SMP0031700 | 18 | 11 | 1369 | 531 |
TP53,CBL,PIK3R1,MYC,BAD,CRKL,BCL2L1,MDM2,STAT5A,JAK2,CDKN1B |
| 4.508e-02 | -3.10 | BCR-ABL Action in CML Pathogenesis | SMPDB pathways | SMP0031692 | 18 | 11 | 1369 | 531 |
CRKL,BAD,MYC,CDKN1B,PIK3R1,JAK2,CBL,MDM2,STAT5A,BCL2L1,TP53 |
| 4.508e-02 | -3.10 | Bafetinib Inhibition of BCR-ABL | SMPDB pathways | SMP0031699 | 18 | 11 | 1369 | 531 |
CDKN1B,MYC,PIK3R1,BAD,CRKL,BCL2L1,TP53,JAK2,STAT5A,MDM2,CBL |
| 4.508e-02 | -3.10 | P53 Signaling Pathway | SMPDB pathways | SMP0063782 | 18 | 11 | 1369 | 531 |
CDKN1A,TIMP3,CDK4,RB1,TP53,CCND1,GADD45B,BAX,CCNB1,MDM2,CDK1 |
| 4.508e-02 | -3.10 | Nilotinib Inhibition of BCR-ABL | SMPDB pathways | SMP0031697 | 18 | 11 | 1369 | 531 |
JAK2,MDM2,STAT5A,BCL2L1,CDKN1B,CBL,TP53,CRKL,BAD,MYC,PIK3R1 |
| 4.508e-02 | -3.10 | Imatinib Inhibition of BCR-ABL | SMPDB pathways | SMP0031694 | 18 | 11 | 1369 | 531 |
MYC,PIK3R1,BAD,CRKL,TP53,CBL,CDKN1B,BCL2L1,JAK2,MDM2,STAT5A |
| 4.508e-02 | -3.10 | Bosutinib Inhibition of BCR-ABL | SMPDB pathways | SMP0031698 | 18 | 11 | 1369 | 531 |
CDKN1B,MYC,PIK3R1,BAD,CRKL,BCL2L1,TP53,JAK2,MDM2,STAT5A,CBL |
| 4.508e-02 | -3.10 | Dasatinib Inhibition of BCR-ABL | SMPDB pathways | SMP0031696 | 18 | 11 | 1369 | 531 |
JAK2,STAT5A,MDM2,CBL,BCL2L1,TP53,BAD,CRKL,CDKN1B,MYC,PIK3R1 |
| 4.509e-02 | -3.10 | HIVEP1 (HIVEP zinc finger 1) | protein interactions | 3096 | 179 | 61 | 19454 | 5460 |
SMAD3,KLF9,YWHAG,YWHAH,VCF2,YWHAB,LHX2,KLF10,RAB1A,BHLHE40,RIGI,PAX6,CAMK2G,SERTAD1,RBBP7,ASF1A,APH1A,EGR2,SOCS3,SOX2,TMEM176A,ELF1,SUPT5H,SP4,APTX,CDK8,IRF8,PHF21A,CREB1,ATXN1L,ELK3,MAD2L1,APEX1,VIRMA,SRPK2,SNRNP40,H2BC9,AR,CSK,HNF1B,CREBBP,CDKN2AIP,FBXW11,YWHAZ,BRCA1,CLK1,EMG1,RAB5A,SOD1,FOS,COIL,SKP1,KDM1A,FXR2,NINJ1,MIEN1,KLF12,KLF4,KLF3,PPARG,SDCBP |
| 4.512e-02 | -3.10 | POLR1G (RNA polymerase I subunit G) | protein interactions | 10849 | 484 | 153 | 19454 | 5460 |
POLR1B,RIT1,PFDN6,PFDN2,FTSJ3,FBXW11,PRPF31,RFC5,RRN3,MYC,ESR2,POLR2B,CBX5,POLR2F,RPS9,GTF2F1,ZMAT2,GTF2F2,POLR3B,VPS72,ZNF174,CMTR1,NFKBIB,PIH1D1,MFAP1,APOBEC3C,ZNF362,SKP1,COIL,NOP53,CFDP1,SLU7,RSBN1L,MED4,KDM2A,IKBKB,H2BC17,DDRGK1,XPO1,RPL6,DDX50,WIF1,LYAR,BUD31,NOP58,ISG20L2,XPO5,POLR2L,RPRD1A,MTA2,POLR2C,ZRANB2,POLR2D,RPN1,JUN,DHX38,E2F4,SUPT5H,TRMT1L,NAA15,SSRP1,RFC2,RAD21,GTF3C3,DHX16,ZNF592,RPAP3,TOP2B,MORC2,CDC73,XPOT,RC3H2,TADA3,MECP2,DNAJC8,NCAPG2,RPL7A,GABPA,POLR3H,FGFBP1,RBMX2,LIG3,CDIPT,PELP1,E2F6,RPRD1B,FAXC,POLR1D,GTF3C4,PSMC4,POLR1H,AATF,BRIX1,HMGB1,RPL4,H2AC13,WDR3,GPX4,RNF113A,NBN,PPM1G,BAP1,HELLS,BRD3,TOPBP1,KPNA1,SMCHD1,KIAA1143,MPHOSPH10,PSMD7,MED21,GTF2E1,PPIL4,CSNK2A1,ZNF24,NFKB1,SURF6,DKC1,POLR2I,PRNP,THOC1,TOP1,RPL35A,PWP2,ALYREF,H2AZ1,TAF2,RNF8,GNAI3,POLR2G,IK,RBM34,SURF4,ZMYM3,RPL15,ZMYM4,RPAP2,WBP11,STRBP,SRFBP1,ARF4,PDRG1,FASTKD5,KPNA2,TOLLIP,DNAAF10,CAMKV,H3C1,RPL3,NKRF,TCOF1,SFXN1,EIF1AD |
| 4.515e-02 | -3.10 | KRT80 (keratin 80) | protein interactions | 144501 | 62 | 24 | 19454 | 5460 |
LCA5L,OSBP,LMO2,HNRNPA1,COPS5,SPOP,ARMC8,DDX39B,CYP17A1,HSPA8,PIAS1,MEPCE,GINS3,SACM1L,TP53,TANK,CCND1,TRAF2,CFTR,IFT57,METTL14,HEXIM1,NUPR1,RNF8 |
| 4.515e-02 | -3.10 | YJU2B (YJU2 splicing factor homolog B) | protein interactions | 81576 | 62 | 24 | 19454 | 5460 |
CLP1,ZNF250,PRPF19,ZNF24,RIOX2,GPX1,KCTD10,GCFC2,TFIP11,JUP,ESS2,SOX2,TRAF2,EEF1A1,H1-5,SEPHS1,ZBTB16,CDC40,RBM22,TRIM63,CWF19L1,HECTD3,EFHC1,RCCD1 |
| 4.515e-02 | -3.10 | MTMR7 (myotubularin related protein 7) | protein interactions | 9108 | 62 | 24 | 19454 | 5460 |
CTNND1,VPS16,CYTH2,GTF2I,TSR3,HUWE1,GFM1,HSPD1,RARS1,MRPS34,VPS33A,CTBP1,VIPAS39,CCNH,GFPT1,MTMR6,CCT5,PPP5C,STK3,GNAI2,CCT7,RALGAPA2,SAV1,HNRNPC |
| 4.515e-02 | -3.10 | PRSS8 (serine protease 8) | protein interactions | 5652 | 62 | 24 | 19454 | 5460 |
AGK,MAD2L1,RAMP3,ESR2,SRC,TREML1,TUBA1B,SPINT2,BRINP2,KLK5,MCAT,CFC1,LAMP3,CAMK2G,DCP2,GPAA1,KLHL15,SFTPC,FURIN,GTF2H4,B3GALT4,LEAP2,CLEC2B,HYAL2 |
| 4.515e-02 | -3.10 | ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3) | protein interactions | 64411 | 62 | 24 | 19454 | 5460 |
RBBP7,TNKS2,INPPL1,ARHGEF6,ATG16L1,TOP3B,RFXANK,CD2AP,TRIM35,SPPL3,TUBB,CIB3,CRYBB3,EEF1AKMT3,NFKBIB,CIB2,PTEN,MYC,UBXN6,ATG7,XPO1,HSPB8,H2BC9,SAMHD1 |
| 4.515e-02 | -3.10 | ZNF184 (zinc finger protein 184) | protein interactions | 7738 | 62 | 24 | 19454 | 5460 |
FGF13,LLPH,CBX3,PPAN,RPL31,RPL3,EWSR1,NPM3,RPL17,UTP23,RPL28,SRSF4,CUL3,ZNF668,RPL26,UBP1,KRR1,FGFBP1,PRKRA,PRR3,RPL7,RPL13A,RPS10,VIRMA |
| 4.518e-02 | -3.10 | HOMER1 (homer scaffold protein 1) | protein interactions | 9456 | 96 | 35 | 19454 | 5460 |
ACTB,PRNP,GRM1,FBXO22,HOMER1,NCKAP1,FCHSD2,VIRMA,TNIK,GRIA1,HOMER3,TRPC1,YWHAZ,TXNIP,MED4,YWHAB,UBE2H,EMILIN1,SYCE3,INSYN1,AGAP2,TPM3,SGF29,ADIPOQ,RNF41,CDC42EP4,BAP1,GRAMD2B,SPOPL,PRPSAP1,STK26,IFT57,GRIK1,STX12,ATG16L1 |
| 4.518e-02 | -3.10 | MAP3K20 (mitogen-activated protein kinase kinase kinase 20) | protein interactions | 51776 | 96 | 35 | 19454 | 5460 |
RPS20,EZH1,PHB1,MAP2K6,PSPC1,ESR2,SRPK2,RPL10,DDAH2,TCEAL7,ZNF593,MPP1,SPCS1,YWHAH,ANAPC15,YWHAG,XPO1,SFN,WWP2,MYC,YWHAB,CRMP1,YWHAZ,RAB5A,EMC2,PSENEN,CDC42,MAP2K3,TP53,RAF1,CCDC69,SMARCB1,PARD6A,ZFP1,EZH2 |
| 4.518e-02 | -3.10 | RPAP1 (RNA polymerase II associated protein 1) | protein interactions | 26015 | 96 | 35 | 19454 | 5460 |
HSPD1,HSPA8,DHX9,BAG2,KRAS,FBXW7,MEPCE,TOP3B,PPIL3,POLR1D,POLR2G,POLR2C,SRP72,CCNF,CRYBB3,LMBR1L,POLR2L,EEF1AKMT3,GPN2,CSNK2B,IGBP1,MAGED2,POLR3B,LRRC61,POLR2B,EGLN3,CUL3,XPO1,HNRNPA1,CSNK2A1,DNAJC5,IGF2BP1,HAX1,DNAJC7,RIT1 |
| 4.521e-02 | -3.10 | TIMM50 (translocase of inner mitochondrial membrane 50) | protein interactions | 92609 | 241 | 80 | 19454 | 5460 |
GTF2I,CYFIP2,NME4,KDM1A,PAFAH1B2,FBXW7,ADRB2,PHB2,WASF3,HSPA5,RPA3,HSPA8,NMRAL1,EP300,MTDH,DCTN4,RPA2,GRM2,FGFR1,COQ8B,GABRA1,TIMM13,CFTR,SMURF1,CBX5,PARL,VIRMA,MAD2L2,NCKAP1,CCNF,NFKBIA,PELO,PTPMT1,RIT1,ILK,UBE2H,MYC,CUL3,TOMM40,CHCHD2,KRAS,CBX7,TRIM37,NDUFA4,SFXN1,IGF1R,BPIFB1,VAMP2,CHMP4C,JCHAIN,OTULIN,RNF8,RAF1,IPO8,TP53,TUBA1A,CTDSP2,TOMM7,ISG15,ERLIN2,FZR1,MDM2,ELK1,EGLN3,TOMM70,SLC25A12,COX14,AIFM1,SDHB,SYNCRIP,RAB35,PHB1,TUBG1,SHC1,SNRNP70,ATG9A,WWP2,HDAC6,YWHAG,MAP3K14 |
| 4.522e-02 | -3.10 | oxygen transport | biological process | GO:0015671 | 15 | 8 | 18204 | 5365 |
HBA1,HBM,NGB,CYGB,HBB,HBE1,IPCEF1,BPGM |
| 4.522e-02 | -3.10 | negative regulation of amino acid transport | biological process | GO:0051956 | 15 | 8 | 18204 | 5365 |
NPY5R,LEP,RGS2,ARL6IP5,ADORA1,SLC43A2,TNF,GABBR1 |
| 4.522e-02 | -3.10 | cellular response to interleukin-17 | biological process | GO:0097398 | 15 | 8 | 18204 | 5365 |
TRAF3IP2,CXCL10,IL17F,NFKB1,SOCS3,TRAF2,TRAF6,IL1B |
| 4.522e-02 | -3.10 | regulation of dendritic cell differentiation | biological process | GO:2001198 | 15 | 8 | 18204 | 5365 |
FCGR2B,MIR223,LGALS3,HMGB1,LILRB1,AGER,TMEM176A,TMEM176B |
| 4.522e-02 | -3.10 | mucus secretion | biological process | GO:0070254 | 15 | 8 | 18204 | 5365 |
VAMP8,ADORA1,VAMP3,PRKCE,AGR2,FOSL2,TRAF3IP2,VAMP2 |
| 4.522e-02 | -3.10 | tertiary alcohol metabolic process | biological process | GO:1902644 | 15 | 8 | 18204 | 5365 |
AKR7A2,CYP11B1,CBR4,AKR1C1,AKR1C2,AKR1B1,CYP11B2,AKR1A1 |
| 4.522e-02 | -3.10 | glycosylceramide metabolic process | biological process | GO:0006677 | 15 | 8 | 18204 | 5365 |
B3GALT1,B3GALT2,GALC,GAL3ST1,B4GALT3,UGCG,ST6GALNAC3,FA2H |
| 4.522e-02 | -3.10 | positive regulation of exosomal secretion | biological process | GO:1903543 | 15 | 8 | 18204 | 5365 |
SDC4,HGS,TSG101,CHMP2A,SDCBP,VPS4B,IFNG,VPS4A |
| 4.522e-02 | -3.10 | pyrimidine ribonucleoside catabolic process | biological process | GO:0046133 | 15 | 8 | 18204 | 5365 |
APOBEC3D,DCTD,APOBEC3H,APOBEC3B,APOBEC3G,APOBEC3F,APOBEC3A,APOBEC3C |
| 4.522e-02 | -3.10 | pyrimidine ribonucleoside metabolic process | biological process | GO:0046131 | 15 | 8 | 18204 | 5365 |
APOBEC3D,APOBEC3A,APOBEC3F,APOBEC3G,APOBEC3B,APOBEC3H,DCTD,APOBEC3C |
| 4.522e-02 | -3.10 | response to interleukin-17 | biological process | GO:0097396 | 15 | 8 | 18204 | 5365 |
TRAF6,IL1B,TRAF3IP2,CXCL10,NFKB1,IL17F,SOCS3,TRAF2 |
| 4.522e-02 | -3.10 | regulation of transcription of nucleolar large rRNA by RNA polymerase I | biological process | GO:1901836 | 15 | 8 | 18204 | 5365 |
PIH1D1,MACROH2A1,MARS1,SMARCB1,SIRT7,DEDD,NOP53,MACROH2A2 |
| 4.522e-02 | -3.10 | DNA strand elongation involved in DNA replication | biological process | GO:0006271 | 15 | 8 | 18204 | 5365 |
POLD2,RFC3,PCNA,MCM3,RFC4,POLE3,LIG3,MCM4 |
| 4.522e-02 | -3.10 | intracellular potassium ion homeostasis | biological process | GO:0030007 | 15 | 8 | 18204 | 5365 |
KCNMA1,SLC12A2,ATP1A2,ATP1B1,ATP1A1,ATP1B3,ATP1A3,KCNJ2 |
| 4.522e-02 | -3.10 | negative regulation of type 2 immune response | biological process | GO:0002829 | 15 | 8 | 18204 | 5365 |
NDFIP1,BCL6,IFNA2,CCR2,SOCS5,IFNB1,STAT6,ARG2 |
| 4.522e-02 | -3.10 | nodal signaling pathway | biological process | GO:0038092 | 15 | 8 | 18204 | 5365 |
TGIF2,ACVR1C,NOG,CFC1,SMAD2,WIF1,SMAD3,ACVR1B |
| 4.522e-02 | -3.10 | neutrophil activation involved in immune response | biological process | GO:0002283 | 15 | 8 | 18204 | 5365 |
FCER1G,VAMP8,MYD88,VAMP7,TYROBP,SYK,LILRA2,VAMP2 |
| 4.522e-02 | -3.10 | negative regulation of B cell apoptotic process | biological process | GO:0002903 | 15 | 8 | 18204 | 5365 |
BCL10,BCL6,SLC39A10,ORMDL3,FOXP1,PDCD1,MIF,IL2 |
| 4.522e-02 | -3.10 | negative regulation of viral transcription | biological process | GO:0032897 | 15 | 8 | 18204 | 5365 |
TRIM27,TRIM8,UBP1,TRIM62,TRIM21,TRIM11,TRIM32,HEXIM1 |
| 4.522e-02 | -3.10 | negative regulation of osteoblast proliferation | biological process | GO:0033689 | 15 | 8 | 18204 | 5365 |
EIF2AK2,MIR675,SMAD3,NF2,GREM1,MIR9-1,ATRAID,SFRP1 |
| 4.522e-02 | -3.10 | regulation of vascular wound healing | biological process | GO:0061043 | 15 | 8 | 18204 | 5365 |
SLC12A2,MIR1298,MIR34A,TNF,CXCR4,FOXC2,TNFAIP3,XBP1 |
| 4.528e-02 | -3.09 | positive regulation of cell cycle G1/S phase transition | biological process | GO:1902808 | 68 | 27 | 18204 | 5365 |
MIR214,MIR208A,MIR495,PLCB1,MIR222,RGCC,AKT1,MIR221,AIF1,PHB2,CCND1,LSM10,MIR519D,CYP1A1,CDC73,MDM2,DDRGK1,MEPCE,RRM1,UBE2E2,TERT,PAGR1,FGF10,EZH2,CCND3,MIR29A,ADAMTS1 |
| 4.528e-02 | -3.09 | cellular response to hydrogen peroxide | biological process | GO:0070301 | 68 | 27 | 18204 | 5365 |
NQO1,TOP2B,PCGF2,AIFM1,SRC,CDK1,HSPA8,CYP1B1,BECN1,KLF4,FXN,STAT6,HDAC6,PPIF,OSER1,RHOB,NFE2L2,MDM2,TNFAIP3,IL6,TXN,PCNA,MAP1LC3A,MIR107,EZH2,RPS3,IL18BP |
| 4.528e-02 | -3.09 | negative regulation of interleukin-6 production | biological process | GO:0032715 | 68 | 27 | 18204 | 5365 |
MIR149,MIR98,MIR140,CD200,LILRB4,SELENOS,TLR4,MIR146A,SOCS5,GHRL,PTPN22,FOXP3,MIR206,MIR132,MIR338,TNFAIP3,MIR195,NMBR,CSK,CD200R1,TNF,MIR204,MIR105-1,MIR101-1,CX3CL1,MIR708,IL10 |
| 4.529e-02 | -3.09 | GKAP1 (G kinase anchoring protein 1) | protein interactions | 80318 | 44 | 18 | 19454 | 5460 |
LARP4B,DNAJC2,SDCBP,HGS,MFAP1,PHOSPHO2,ZCCHC10,TOP3B,GKAP1,RPGRIP1L,STAU1,RPP25L,FXR2,NDN,SH3BP4,HSD11B1,RPS20,RPS24 |
| 4.529e-02 | -3.09 | MPP3 (MAGUK p55 scaffold protein 3) | protein interactions | 4356 | 44 | 18 | 19454 | 5460 |
SRPK2,ZNF655,LIN7C,RAB31,MTMR2,RPS2,MDH1,ARL2BP,GNG7,NOA1,PKNOX1,FBXO7,TIRAP,TRAF2,KBTBD4,TOP3B,LIN7B,HSH2D |
| 4.529e-02 | -3.09 | KLHL7 (kelch like family member 7) | protein interactions | 55975 | 44 | 18 | 19454 | 5460 |
KPNA6,FGF1,NUP153,CUL3,MOV10,RPL23,MSRB3,CDC23,ANAPC4,YWHAZ,SDC2,NUP50,HAPSTR1,KLHL7,STAU1,ACTB,CAMKV,STAT5A |
| 4.529e-02 | -3.09 | MND1 (meiotic nuclear divisions 1) | protein interactions | 84057 | 44 | 18 | 19454 | 5460 |
VRK1,TTC9C,PYM1,EIF1AD,PPP1R12A,DNM2,METTL18,SRP54,IK,CHMP1A,DNAJC2,RTF2,EIF1AX,MAP1S,EPS8,PDIA3,METTL15,BTF3L4 |
| 4.529e-02 | -3.09 | GAS2L1 (growth arrest specific 2 like 1) | protein interactions | 10634 | 44 | 18 | 19454 | 5460 |
MAPRE2,RIGI,CDKN2C,HECTD3,CAPZA2,CRTAP,P3H1,CKS2,MAPRE1,SNX5,TMOD1,GNB1L,E2F4,CCNB1,TOP3B,RBM12,PPP1CB,CD2AP |
| 4.529e-02 | -3.09 | SLC9A6 (solute carrier family 9 member A6) | protein interactions | 10479 | 44 | 18 | 19454 | 5460 |
TLCD2,COA1,DNAJC30,LGALS3,SPCS1,CDK20,FKRP,TMEM87A,SERINC1,RELL2,LGALS8,TMEM164,FUT8,SLC19A2,YIPF3,MBLAC2,IFNGR1,CFTR |
| 4.529e-02 | -3.09 | FNBP1L (formin binding protein 1 like) | protein interactions | 54874 | 44 | 18 | 19454 | 5460 |
HNRNPK,RHOJ,WASL,STAU1,HNRNPL,SNX24,ATP6AP2,PACSIN3,PML,FOS,DNM2,FGFR1,ATG3,EZH2,RBPJ,USP13,SF3A1,CDC42 |
| 4.532e-02 | -3.09 | H4C16 (H4 histone 16) | protein interactions | 121504 | 134 | 47 | 19454 | 5460 |
ORC5,COPS5,HDAC6,AGR2,MGMT,BRD3,FOLR1,EED,RB1,PGR,CAND1,TMPO,MDM2,LRWD1,ANP32A,H2AX,EZH2,CTNNBL1,RBBP7,CNR1,ASF1A,RAD21,CREBBP,CUL2,PRMT6,CUL3,PRKACB,PRMT5,ALB,TRIM24,USP16,HPF1,SIAH1,IFI6,RBBP4,CBX5,VIRMA,CDKN1A,ELK4,METTL14,GSTP1,TCF19,WTAP,RAG1,PRKCB,HDAC5,EP300 |
| 4.545e-02 | -3.09 | Cytochrome P450 | gene3d domains | 1.10.630.10 | 58 | 23 | 14470 | 4137 |
CYP11B2,CYP2C18,CYP1A1,CYP3A5,CYP27A1,CYP1B1,CYP3A43,CYP11B1,CYP4F12,CYP26A1,CYP2R1,CYP2D6,CYP4V2,CYP27B1,CYP21A2,CYP4F8,CYP7A1,CYP2C8,CYP39A1,CYP2C9,CYP4F22,CYP17A1,CYP2F1 |
| 4.545e-02 | -3.09 | GC (GC vitamin D binding protein) | protein interactions | 2638 | 59 | 23 | 19454 | 5460 |
HBB,SERPINA1,CCR1,SERPINA3,TF,CLU,CCND3,LCN1,EGFL8,RPS6KA4,AGPAT1,CDC73,HSP90AA1,PIK3R3,SCGB1D1,HP,ACTB,FBXO22,HYPK,CTSB,LRIF1,ACTA2,HYCC1 |
| 4.545e-02 | -3.09 | TTI2 (TELO2 interacting protein 2) | protein interactions | 80185 | 59 | 23 | 19454 | 5460 |
APLNR,SNRPD3,LMBR1L,HSP90AA1,TYROBP,RIT1,COX16,SLC2A1,OPRM1,GPR17,LRRTM2,TNFSF12,CD80,KRAS,NPTN,RUVBL1,RPAP3,RUVBL2,CD40,SLC39A9,TTI2,PIH1D1,COX6C |
| 4.545e-02 | -3.09 | VEGFA (vascular endothelial growth factor A) | protein interactions | 7422 | 59 | 23 | 19454 | 5460 |
SP1,NRP1,HNRNPD,HSP90AA1,HGS,CRYAB,BRCA1,ADAMTS1,UBIAD1,CFTR,AKT1,MDM2,RIGI,APEX1,CLU,TMEM237,HNRNPL,GJB1,PTPRZ1,GPC1,RB1,VEGFA,FOS |
| 4.545e-02 | -3.09 | KDM4B (lysine demethylase 4B) | protein interactions | 23030 | 59 | 23 | 19454 | 5460 |
HNRNPL,FBXO22,TCP1,COIL,ESR2,VIRMA,CCT7,RPA3,STUB1,CCT8,SMU1,BAG2,CCT2,RPA2,CHORDC1,MED10,HSP90B1,TRAF6,RTF2,HSPA14,FGFR1OP2,AKT1,CCT5 |
| 4.545e-02 | -3.09 | CRTC2 (CREB regulated transcription coactivator 2) | protein interactions | 200186 | 59 | 23 | 19454 | 5460 |
YWHAB,PPP3CA,COP1,CDC23,YWHAZ,TRAF6,RC3H2,XPO1,YWHAG,NTAQ1,ARL6IP6,YWHAH,NUP35,EGLN3,MDM2,KCTD3,CREB1,ACTR2,CDKN1A,SUFU,TP53,EP300,ATPAF2 |
| 4.545e-02 | -3.09 | ATP6V0D2 (ATPase H+ transporting V0 subunit d2) | protein interactions | 245972 | 59 | 23 | 19454 | 5460 |
SLC2A1,LAMTOR1,NDUFB8,ABITRAM,SLC6A1,PLPP4,TMEM199,CENPP,RBM15B,COX11,YES1,ADRM1,SPPL3,ATP6AP2,RPS3,PHF12,CDCA3,NICN1,ATP6V1G2,KRAS,CERS2,PAX6,TMEM185A |
| 4.548e-02 | -3.09 | IL1HBGF | prints domains | PR00262 | 23 | 11 | 5227 | 1528 |
FGF12,FGF10,FGF7,FGF13,FGF17,FGF22,FGF3,IL1B,FGF16,FGF23,FGF1 |
| 4.548e-02 | -3.09 | vesicle coat | cellular component | GO:0030120 | 63 | 25 | 19108 | 5553 |
DIPK2A,COPE,NECAP1,AP1G2,AP2S1,AFTPH,AP2M1,TBC1D5,SEC13,KLHL12,NECAP2,NCALD,AP1S2,AP1M1,AP2A1,TMED7,COPZ2,SYNRG,ARCN1,TMED3,SEC23A,SAR1B,CLBA1,CIDEB,SGIP1 |
| 4.548e-02 | -3.09 | Znf_RING_CS | interpro domains | IPR017907 | 166 | 59 | 18521 | 5414 |
TRAF6,RC3H2,RNF5,TRIM15,RNF222,TRIM46,TRIM10,CBLL1,PCGF2,PML,TRIM45,TRIM22,TRIM6,TRIM32,RNF40,TRIM68,RNF10,RNF141,TRIM3,COP1,TRIM24,RNF14,RBCK1,TRIM63,RNF41,RNF146,TRAF2,TOPORS,TRIM52,TRIM54,TRIM23,TRIM11,RAG1,LNX2,CBL,TRIM35,RING1,RNF144B,TRIM62,RNF182,TRIM21,RNF8,MNAT1,TRIM27,TRIM8,RNF187,RNF113A,BFAR,RNF208,PCGF6,RNF20,TRIM34,PCGF3,BRCA1,TRIM5,SHPRH,TRIM36,TRAF7,RNF39 |
| 4.549e-02 | -3.09 | positive regulation of nervous system development | biological process | GO:0051962 | 296 | 101 | 18204 | 5365 |
STK11,LRRC24,IL1RAP,PRMT5,TBC1D24,SEMA5A,CXCR4,HDAC6,CXCL12,IL1B,MME,WNT7A,LRRTM2,OXTR,TRIM32,CTNNB1,WNT2,NKX6-2,MAP1B,CX3CR1,SLITRK2,CX3CL1,ASPA,KRAS,TNF,RND2,XRCC5,LRTM2,MIR221,DICER1,LRRN1,CBLN1,FZD3,TLR2,NLGN2,FXR2,KIT,RHEB,MIR222,FLRT3,NEFL,GHRL,LRRC4B,ZNF365,ADNP,LTA,ASIC2,L1CAM,PPP1CC,MAP2K1,KDM1A,NRP1,DISC1,OPRM1,VEGFC,IL6ST,SYNDIG1,DAG1,CRABP2,PLXNC1,ASPM,MIR142,LRRTM3,IL6,SLITRK5,HAPLN2,ID4,EPHA4,NLGN1,IFNG,PAFAH1B1,LRRTM1,TIAM1,PTN,EGR2,UFL1,CBLN2,FLRT2,NTRK2,CLSTN3,ANAPC2,FZD4,GPRASP3,NPTN,AMIGO1,TNFRSF1B,SMARCD3,TSPO,NR2E1,SMURF1,EFNA5,BMPR2,PTPRZ1,SEMA7A,VEGFA,IL34,MYRF,SLITRK1,MECP2,PAX6,TPBG |
| 4.561e-02 | -3.09 | SASH1 (SAM and SH3 domain containing 1) | protein interactions | 23328 | 47 | 19 | 19454 | 5460 |
CRKL,YWHAB,FOXP1,EXOC8,YWHAZ,IKBKB,YWHAH,YWHAG,SFN,SPTBN1,VIRMA,IRAK4,SECISBP2L,TNKS2,SNX1,KIF3B,C1D,CTNNA1,MYD88 |
| 4.561e-02 | -3.09 | BST2 (bone marrow stromal cell antigen 2) | protein interactions | 684 | 47 | 19 | 19454 | 5460 |
TMPO,ESR2,TAB1,VDAC1,TOLLIP,MYD88,VDAC2,TMEM106B,PIGK,CYB5R3,TAB2,VMP1,HGS,TFRC,CAPZA2,CD81,HDAC6,MAP1LC3B,FAM20C |
| 4.561e-02 | -3.09 | NOL3 (nucleolar protein 3) | protein interactions | 8996 | 47 | 19 | 19454 | 5460 |
H2AZ1,EHD4,TFPT,ETNK2,AASDHPPT,XPNPEP1,KRAS,SPPL3,APEX1,PACSIN3,CSNK2A1,GTF3C4,EHD1,GNPDA2,TRAF6,FAS,NIF3L1,PDCD10,BAX |
| 4.561e-02 | -3.09 | JPT2 (Jupiter microtubule associated homolog 2) | protein interactions | 90861 | 47 | 19 | 19454 | 5460 |
DYRK1A,SAR1B,STAU1,HSPA8,TES,BAP1,RPA3,CCNF,SLC25A20,HSPB1,UBE2H,CNTFR,LMNA,RPA2,BICD2,CDC42,EGR2,TPT1,TP53 |
| 4.561e-02 | -3.09 | HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14) | protein interactions | 51171 | 47 | 19 | 19454 | 5460 |
PCGF6,ILVBL,PHF1,PSMA1,HNRNPL,SREK1IP1,DDIT3,YAF2,SNAPC3,PICK1,NUDT18,E2F6,MPG,GLO1,NTAQ1,DHRS4,CDKN2D,CA8,MAX |
| 4.561e-02 | -3.09 | MOCS3 (molybdenum cofactor synthesis 3) | protein interactions | 27304 | 47 | 19 | 19454 | 5460 |
NUBP2,CLPB,HSPA8,EEF1AKMT3,IRF3,GXYLT1,VPS16,NMI,CA10,KRAS,MGARP,DDX39A,ISX,RIT1,UBE2H,HERC4,KLC2,KLK5,FAS |
| 4.561e-02 | -3.09 | CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1) | protein interactions | 84254 | 47 | 19 | 19454 | 5460 |
RPS10,RUVBL1,RUVBL2,FHL3,TRIM11,GARRE1,HSP90AA1,SF3B5,ANXA7,YWHAB,NSA2,CAMK1,CTSA,YWHAG,YWHAH,CFTR,CSNK1E,BRINP1,AKT1 |
| 4.561e-02 | -3.09 | TMCC2 (transmembrane and coiled-coil domain family 2) | protein interactions | 9911 | 47 | 19 | 19454 | 5460 |
DPY30,FAM161A,AKT1,KXD1,TOP3B,ZNF250,ZNF581,PRPF31,HGS,ZNF688,FKBP10,CDR2,EIF4E2,ACTA2,CMTR1,HSPD1,ADRB2,ACTB,TMCC2 |
| 4.561e-02 | -3.09 | PTGER4 (prostaglandin E receptor 4) | protein interactions | 5734 | 47 | 19 | 19454 | 5460 |
NUBP2,CFAP298,CDPF1,SRC,VIRMA,PSMC1,PSEN1,ATXN10,WDR19,CRADD,ST13,HMOX2,ACTN4,NUP153,VSTM2A,PRDX1,RTF2,FEM1A,SPP1 |
| 4.561e-02 | -3.09 | PRPF39 (pre-mRNA processing factor 39) | protein interactions | 55015 | 47 | 19 | 19454 | 5460 |
KCTD15,CAND1,RBM22,FBXW7,TOLLIP,WDR44,HDAC5,FOXS1,SMAD4,FBXW11,BRCA1,MYC,RAF1,CUL2,CUL3,COPS5,H2BC9,EXOSC8,CFTR |
| 4.561e-02 | -3.09 | NDRG2 (NDRG family member 2) | protein interactions | 57447 | 47 | 19 | 19454 | 5460 |
GGT7,FBXO11,HSPA8,NRSN1,RABAC1,PICK1,CLN8,SPPL3,RNF115,TUSC2,CCR4,TRIM32,SSBP2,DDX39A,ATP1B1,STX17,CCR1,ATP1A1,AGPAT1 |
| 4.561e-02 | -3.09 | SACS (sacsin molecular chaperone) | protein interactions | 26278 | 47 | 19 | 19454 | 5460 |
SOD1,PICK1,ELOF1,P4HA2,EFNB1,UBE3A,ALB,PSMA3,HNRNPA0,TRIM29,ADRB2,POLR1H,VIRMA,TP53,USP3,GPR17,ACTN4,RPA2,DNAJC7 |
| 4.562e-02 | -3.09 | Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways | WikiPathways | WP706 | 162 | 69 | 5310 | 1910 |
NFKB1,ESR2,IL1A,SCN3B,TNF,YWHAH,GNB3,CTNNB1,MIR210,PLP1,SLC6A4,EP300,CHRNA7,NFYA,PKNOX1,PRKACB,YWHAZ,NTRK2,GAPDH,KCNJ8,CDCA7L,CHRNB2,AQP4,CREB1,HTR2A,SNAP25,CXCL8,TPH2,SPTBN1,HSPD1,GJA1,FMO3,NOS1AP,MIR16-1,SLC25A4,SST,SP1,HADHA,MIR130A,TF,AR,MECP2,MEF2C,NKX3-1,VAMP2,GABRA1,VIPR1,JUN,CREBBP,POU5F1,IL1B,YWHAG,BHLHE40,IL10,SLC1A3,SNTA1,TACR1,TAC1,SOX2,HTR1A,CAV3,IL13,ATP1A3,IL6,EGR1,YWHAB,TPPP,HSP90B1,VEGFA |
| 4.563e-02 | -3.09 | carboxylic acid transmembrane transport | biological process | GO:1905039 | 131 | 48 | 18204 | 5365 |
SLC7A9,SLC7A1,KCNJ10,ABCB1,SLC43A2,SLC7A11,ABCC5,UCP2,SLC13A5,SLC2A1,CPT1B,SLC25A1,SLC23A2,CPT2,SLC1A2,SLC1A1,SLC6A7,SLC25A21,SLC5A6,SLC7A8,LRRC8A,SLC1A3,LRRC8B,SFXN2,GRM1,SLC35D1,MPC1,SFXN1,SLC17A5,SLC25A26,CLN8,SLC38A9,LRRC8D,CD36,SLC25A11,SLC38A2,SLC38A1,SLC25A10,SLC25A12,SLC38A3,SLC25A32,TSPO2,SLC25A20,PSEN1,ARL6IP5,LRRC8C,SLC6A8,SLC16A1 |
| 4.564e-02 | -3.09 | Cytidine Deaminase, domain 2 | gene3d domains | 3.40.140.10 | 29 | 13 | 14470 | 4137 |
APOBEC3A,DCTD,PSMD7,APOBEC3D,STAMBPL1,APOBEC3C,STAMBP,PSMD14,APOBEC3G,COPS5,APOBEC3H,APOBEC3B,APOBEC3F |
| 4.567e-02 | -3.09 | MRPL54 (mitochondrial ribosomal protein L54) | protein interactions | 116541 | 56 | 22 | 19454 | 5460 |
SNRNP70,MRPL18,LMNA,HEXIM1,PPME1,MRPL11,MTG2,MYC,MRPL12,MRPL16,MRPL9,SOX2,MRPL50,MRPL40,MRPS7,VPS16,MEPCE,MTG1,PHB1,FAM50B,MRPL53,MRPL13 |
| 4.567e-02 | -3.09 | ZNF524 (zinc finger protein 524) | protein interactions | 147807 | 56 | 22 | 19454 | 5460 |
LBR,MAK16,IPO8,ZNF526,CHMP1A,ADNP,EZH2,ZC4H2,THG1L,PICK1,TWNK,SERTAD2,POLDIP2,MEPCE,MDFI,DDX50,RPL10A,FTSJ3,KBTBD6,SURF6,RSL24D1,SPPL3 |
| 4.567e-02 | -3.09 | HDHD3 (haloacid dehalogenase like hydrolase domain containing 3) | protein interactions | 81932 | 56 | 22 | 19454 | 5460 |
PLSCR4,DDAH1,ACO1,FEN1,CMPK1,NDUFAB1,ARCN1,PIH1D1,VAC14,MTHFD2L,HINT2,HSCB,POLDIP2,ATG9A,ACO2,MOV10,MICB,PCCB,MTPN,PRNP,DDAH2,CLIC4 |
| 4.567e-02 | -3.09 | AFTPH (aftiphilin) | protein interactions | 54812 | 56 | 22 | 19454 | 5460 |
TUBB4B,VAPB,RAB4A,AP1S2,DDAH1,INSIG2,MAP1LC3B,SYNRG,KRAS,STX7,AP1M1,UBE3A,ATG9A,RAB11A,SFN,YWHAG,XPO1,YWHAH,STX6,TUBA1B,GSK3A,AP1G2 |
| 4.567e-02 | -3.09 | TMLHE (trimethyllysine hydroxylase, epsilon) | protein interactions | 55217 | 56 | 22 | 19454 | 5460 |
BTG3,IMMP2L,MRPS17,RASL10B,SDHAF4,FAHD1,AMACR,EXD2,SLC25A10,HSPD1,KLK5,ACAA2,PDHA1,LDHAL6B,TULP3,WWP2,MRM2,CUL3,ETFBKMT,FAM174A,PNPLA4,CSNK1E |
| 4.567e-02 | -3.09 | FBXL18 (F-box and leucine rich repeat protein 18) | protein interactions | 80028 | 56 | 22 | 19454 | 5460 |
MYC,MDFI,WWP2,COPS5,FBXL7,ATG7,ZNF207,TFCP2,EZH2,CHMP1A,WWP1,HSP90AA1,PLSCR1,PNMA1,GNA11,PSMA3,FHL3,TTC9C,HNRNPK,SKP1,VIRMA,TRAF1 |
| 4.567e-02 | -3.09 | IVD (isovaleryl-CoA dehydrogenase) | protein interactions | 3712 | 56 | 22 | 19454 | 5460 |
RMND1,RIGI,FASTKD5,PSEN1,LYRM2,ETFA,HSCB,GPSM3,FAHD1,HINT2,PNMA1,SLC25A10,STK11,ACAA2,QRSL1,MGAT5B,HMOX2,H1-3,PMPCA,TXNRD2,ETFB,MTG2 |
| 4.567e-02 | -3.09 | NOL4 (nucleolar protein 4) | protein interactions | 8715 | 56 | 22 | 19454 | 5460 |
CHMP2A,STAT5A,PHF21A,ZMYM2,LCORL,ZNF24,CSK,AKT1,CXXC1,USP30,KDM1A,KRAS,APPBP2,CSNK1A1,ADNP,SKA3,ZMYM6,CTBP1,KLF3,KLF12,ZMYM3,SNAPC5 |
| 4.567e-02 | -3.09 | MYH7B (myosin heavy chain 7B) | protein interactions | 57644 | 56 | 22 | 19454 | 5460 |
CHTOP,CKB,CCT2,CYC1,PDCL,SP1,CCT5,ACO2,CFTR,TPM3,TMEM183A,DDX39A,SEC62,ACTN4,ISG15,TCP1,COPS7B,POLDIP3,CCT7,NCBP2,CCT8,HSPA8 |
| 4.568e-02 | -3.09 | TNPO3 (transportin 3) | protein interactions | 23534 | 228 | 76 | 19454 | 5460 |
COIL,NPTN,TRA2B,HSCB,RP2,VIPR1,CLK1,ARPC2,SQSTM1,EP300,AKAP1,RPA3,CD40,MFAP1,NCOA5,P2RY12,RPA2,LMNA,GPR35,STOM,FAXC,HCST,SNRNP27,CFTR,FAM234A,VIRMA,ESR2,PTEN,S1PR4,SCN2B,LMBR1L,CCNF,TNFRSF1B,TYROBP,PFDN6,RIT1,CIRBP,LMNB1,RBM27,GPR17,OPRM1,CUL3,RIGI,AHCYL1,KRAS,CAMK2G,CD80,SEMA4C,EFNB1,UBE3A,PPP1R12A,RUSF1,GLCE,CYB5B,SIGLECL1,CA14,NME1,PPP2R1A,SOX2,FEN1,COMTD1,TOP3B,NAA11,ILVBL,XXYLT1,STX5,HRAS,CD274,SRSF1,ST6GAL1,PPP3CA,BRD3,YWHAG,P2RY10,DDRGK1,FAM174A |
| 4.575e-02 | -3.08 | BBOX | smart domains | SM00336 | 72 | 26 | 9717 | 2575 |
TRIM44,TRIM3,PML,TRIM54,TRIM6,TRIM63,TRIM34,TRIM24,TRIM10,TRIM23,TRIM37,TRIM5,TRIM26,TRIM45,TRIM35,TRIM46,TRIM68,TRIM11,TRIM27,TRIM21,TRIM15,TRIM22,TRIM52,TRIM36,TRIM32,TRIM29 |
| 4.577e-02 | -3.08 | EHBP1L1 (EH domain binding protein 1 like 1) | protein interactions | 254102 | 50 | 20 | 19454 | 5460 |
UBXN6,TOP3B,E2F4,RAB11A,CDC42,GGH,MTA2,POLR2C,RRP7A,HRAS,RHOU,EEF1AKMT3,COPS2,SGF29,KRAS,SPTAN1,PRNP,TFG,RAB8B,ESR2 |
| 4.577e-02 | -3.08 | PTAFR (platelet activating factor receptor) | protein interactions | 5724 | 50 | 20 | 19454 | 5460 |
EIF2B2,EIF2B5,PRNP,MFSD3,SLC7A1,PGAP4,RABIF,JAK2,SCAMP2,TMX2,EIF2B3,GOLGA5,ATP1A3,ARMT1,HEXIM1,EPHX1,TM9SF1,TM9SF4,RABL3,YIPF3 |
| 4.577e-02 | -3.08 | UHMK1 (U2AF homology motif kinase 1) | protein interactions | 127933 | 50 | 20 | 19454 | 5460 |
CNOT6L,EDEM2,BTG3,CAPZA1,RIGI,CNOT7,SPPL3,NOP53,MRPL41,EFHC1,TMSB4X,UBE2M,PFDN4,GPBP1L1,AKAP8L,PFDN6,DEPDC1B,NDUFAF3,CNOT2,PFDN5 |
| 4.577e-02 | -3.08 | RFX5 (regulatory factor X5) | protein interactions | 5993 | 50 | 20 | 19454 | 5460 |
AR,CSTF2T,RFXANK,NDUFA2,MOV10,CDC73,PPARG,CFAP298,EWSR1,MRPL53,CREB1,RPA3,APEX1,PAX6,ANKRA2,SRPRB,TRIM37,RFXAP,SPPL3,H3C1 |
| 4.577e-02 | -3.08 | TMEM248 (transmembrane protein 248) | protein interactions | 55069 | 50 | 20 | 19454 | 5460 |
FAM3C,UBFD1,VPS4A,GRM2,SYS1,LACRT,SLC41A1,CSK,TSPAN5,LEPROTL1,UQCRQ,GPR37L1,SYNE4,ANKRD46,KRAS,SSH3,YIF1A,TMEM147,RUSF1,BCL7B |
| 4.577e-02 | -3.08 | DOLPP1 (dolichyldiphosphatase 1) | protein interactions | 57171 | 50 | 20 | 19454 | 5460 |
PLD3,RPN1,RPA2,SSR1,RHOB,SEC62,LAMP3,H2BC9,LAMP2,RAB2A,RAB5C,STX7,LYG2,HSD17B11,PRKCB,LDLR,SEC61B,RAB35,RPA3,TMT1A |
| 4.577e-02 | -3.08 | CHST14 (carbohydrate sulfotransferase 14) | protein interactions | 113189 | 50 | 20 | 19454 | 5460 |
CBLN4,KLRD1,CFTR,GGH,TMEM106A,CLEC2B,LY6H,NCR3,GOLGA5,TAFAZZIN,SDF2L1,TSPAN18,NRSN1,DNASE1L1,LMBR1L,FIBIN,KLK3,PRNP,CLEC12B,DNAJB9 |
| 4.577e-02 | -3.08 | VCAN (versican) | protein interactions | 1462 | 50 | 20 | 19454 | 5460 |
RIGI,CCL8,CXCL10,TNR,SELL,CCL2,GGH,CCL3,CCL5,CCL20,XCL1,CXCL12,TNFAIP6,NCR3,CCL21,IL17F,MSMB,ADAMTS1,SDF2L1,RAB19 |
| 4.577e-02 | -3.08 | TAF11 (TATA-box binding protein associated factor 11) | protein interactions | 6882 | 50 | 20 | 19454 | 5460 |
CCNA2,GTF2E1,NFYB,ZCCHC10,VDR,NFYA,TAF7,TAF2,BRD3,TSNAX,TAF10,TAF9,GTF2F1,TRIM24,APPBP2,SPATA25,CPSF1,GTF2B,TAF11,ACTB |
| 4.578e-02 | -3.08 | CLEC7A (C-type lectin domain containing 7A) | protein interactions | 64581 | 53 | 21 | 19454 | 5460 |
GJB1,FNDC9,SYNE4,CXCL9,BNIP3L,TLCD4,HSPD1,JAGN1,RHOU,AIP,VSIR,FAM3A,CLEC7A,TLR2,FCGR1A,SYK,OPRM1,HNRNPC,SEC22A,CFTR,CTXN3 |
| 4.578e-02 | -3.08 | WIPI1 (WD repeat domain, phosphoinositide interacting 1) | protein interactions | 55062 | 53 | 21 | 19454 | 5460 |
COG1,GOSR1,KCTD15,MRPL41,UBB,ESR2,MRPS7,OPTN,SSBP1,ZNF787,HDHD5,MRPL13,RPS20,IDH2,ACAA2,ATG9A,ATG16L1,ATG101,UQCRC1,EDC3,AR |
| 4.578e-02 | -3.08 | TIMM8B (translocase of inner mitochondrial membrane 8 homolog B) | protein interactions | 26521 | 53 | 21 | 19454 | 5460 |
EGFL8,YBEY,COQ10B,COX4I1,BCKDK,SFXN1,AIFM1,PARL,PLGRKT,SLC25A12,COX14,EGLN3,PHB2,LYZL6,MAP3K14,AURKAIP1,TIMM13,COQ8B,NAA50,PDYN,KLC2 |
| 4.578e-02 | -3.08 | MIS18BP1 (MIS18 binding protein 1) | protein interactions | 55320 | 53 | 21 | 19454 | 5460 |
OIP5,EIF2B5,SNRNP40,FTL,TRIM52,TNFRSF1B,NLE1,DVL2,TMEM74,RMDN3,CDK1,CBX3,RBM7,SP1,CUL3,ING5,MYC,IKZF5,PCBD1,FBXO7,CAV3 |
| 4.580e-02 | -3.08 | SULF2 (sulfatase 2) | protein interactions | 55959 | 115 | 41 | 19454 | 5460 |
NFKBIL1,SDC2,PNMA2,PDP2,COMMD3,NEK7,CCL3,EDDM3B,NOTCH2,EDEM2,MRPS18C,CXXC1,MRPS7,GPIHBP1,HECTD3,RNF113A,COMMD2,KLHL15,DCAF5,CCDC22,NOS1AP,LCN6,H2BC9,CSNK2A1,CSGALNACT2,PRKACB,SPON1,CCDC85B,MYC,ZCCHC10,TSPYL4,G2E3,VIRMA,ESR2,OS9,BRMS1L,DKK3,MRPS9,SIN3A,FBLN5,SDC4 |
| 4.581e-02 | -3.08 | positive regulation of telomere maintenance | biological process | GO:0032206 | 71 | 28 | 18204 | 5365 |
NEK2,ACTL6A,PRKCQ,INO80C,CCT5,TCP1,NBN,TNKS2,INO80E,PPP1R10,TFPT,HNRNPA2B1,CCT8,SLX1A,XRCC5,CCT7,CCT2,DKC1,HNRNPA1,MAPKAPK5,PML,PKIB,TNKS,HNRNPD,CTNNB1,RUVBL2,RUVBL1,NEK7 |
| 4.585e-02 | -3.08 | SCF ubiquitin ligase complex | cellular component | GO:0019005 | 66 | 26 | 19108 | 5553 |
FBXO25,FBXW11,FBXL7,FBXO3,FBXO9,FBXO7,CACYBP,TMEM183A,FBXO42,FBXL14,FBXO31,CKS1B,TRIM21,CUL2,FBXO44,SPSB3,FBXO32,FBXL4,SPSB1,CCNF,FBXL3,FBXW4,FBXW7,FBXL19,SKP1,CKS2 |
| 4.589e-02 | -3.08 | GRAMD1A (GRAM domain containing 1A) | protein interactions | 57655 | 163 | 56 | 19454 | 5460 |
SEC62,OTULINL,ST7,RPA2,GP9,SSR1,CHRNB2,DNAJC3,GRAMD2B,RPA3,DERL1,AKAP1,PXMP2,HSPA5,PCDHB1,DNAJC5,DNAJC10,LMBR1L,CD79B,CCNF,RMDN3,SEC61B,COPE,CLRN2,SEC63,MRPL47,DNAJC25,RPN1,HSPA13,STIM1,ACVR1,CCR1,CTXN1,TMT1A,TLR7,DNAJC30,LRP3,RIGI,FKBP8,CSNK2A1,KCNJ10,ESYT1,DNAJC7,TESK1,HAX1,TMEM30A,ARMC8,STYK1,RAB35,PTPN1,COX4I1,HSD17B11,ARF6,MARCHF4,DNAJC1,TMPO |
| 4.593e-02 | -3.08 | LATS2 (large tumor suppressor kinase 2) | protein interactions | 26524 | 284 | 93 | 19454 | 5460 |
CDKN1A,IDH3B,NOTCH2,WDR77,LNX2,PIH1D1,STK26,SKP1,PKP4,MYC,HSP90AA1,YWHAZ,TAFAZZIN,ANAPC2,PRMT5,PPP5C,FBXO22,SIAH1,PPP2R1A,RAF1,TOP3B,MOB3C,MTA2,PNMA2,EZH2,BAG2,FHL3,CDKN2C,ZYX,DMPK,TRIM37,STK4,CTNNB1,SIAH2,IQSEC1,YWHAH,PPFIBP1,XPO1,YWHAG,CDC26,SAV1,AHSA1,HAX1,CDC23,IKBKB,AK2,FUBP3,STK3,HSP90AB1,CNTROB,HNRNPL,CNP,SIPA1L1,GTF3C4,KDELR2,MET,P3H1,LIN7C,NF2,AR,CEP85,AKT1,CDC16,SMAD2,EPHA2,STK11,DNAJC10,MOB4,TRIM27,STUB1,VIRMA,SRC,DYRK1A,MAP3K3,FNTB,MAP2K3,TP53,CDK4,TBK1,GRAP2,SLC25A10,FKBP8,RIGI,MOB3B,GRSF1,SSX2IP,DNAJC7,BECN1,CDK6,HRAS,MDM2,GRM1,FZR1 |
| 4.602e-02 | -3.08 | ZnF_C2C2 | smart domains | SM00440 | 6 | 4 | 9717 | 2575 |
TCEA2,POLR1H,POLR2I,TCEA1 |
| 4.602e-02 | -3.08 | PKS_KR | smart domains | SM00822 | 6 | 4 | 9717 | 2575 |
DECR2,HSD17B8,CBR4,DHRS3 |
| 4.602e-02 | -3.08 | B561 | smart domains | SM00665 | 6 | 4 | 9717 | 2575 |
CYB561D2,CYBRD1,CYB561,FRRS1 |
| 4.602e-02 | -3.08 | CRA | smart domains | SM00757 | 6 | 4 | 9717 | 2575 |
MAEA,RANBP10,RMND5B,GID8 |
| 4.602e-02 | -3.08 | btg1 | smart domains | SM00099 | 6 | 4 | 9717 | 2575 |
BTG1,BTG2,BTG3,TOB2 |
| 4.605e-02 | -3.08 | ATP2C1 (ATPase secretory pathway Ca2+ transporting 1) | protein interactions | 27032 | 93 | 34 | 19454 | 5460 |
CYB5D2,TSPAN15,LPAR2,EMC2,SLC31A1,EMC1,TACR3,TMEM231,TP53,MGARP,OTULINL,YIPF5,FAF2,GPR35,TMEM165,GTF2IRD1,OGFOD3,OTULIN,S1PR4,LMBR1L,CCNF,PTPN1,HNRNPL,RHOJ,AGK,APEX1,FAM174A,ICAM2,RAB5C,CCR6,LAMP3,GORASP2,LAMTOR1,SPOP |
| 4.605e-02 | -3.08 | TXLNG (taxilin gamma) | protein interactions | 55787 | 93 | 34 | 19454 | 5460 |
SNRNP27,AZI2,TBK1,MAX,TOP3B,KBTBD4,TANK,RPA2,CHAMP1,DNAJC2,CPNE2,ZC3H11A,EP300,RPA3,RPL31,GRAMD2B,PEBP1,KRAS,STAU1,TTC4,BTF3,MOV10,NDC80,USP3,SSX2IP,MED4,UBE2H,BICD2,ZFAND6,MCL1,TRIM44,STUB1,ENO1,VIRMA |
| 4.605e-02 | -3.08 | PTPN3 (protein tyrosine phosphatase non-receptor type 3) | protein interactions | 5774 | 93 | 34 | 19454 | 5460 |
TENT5D,GHR,ILF2,AKR1C1,VDR,MAPKAPK5,SCML1,MYORG,AHCYL1,MRPS7,UBE3A,NXT2,YWHAZ,HSPB1,YWHAB,ANKRD50,DTL,CD247,SFN,MRPS35,ZCCHC10,AKT1,ACOT8,TSEN34,YWHAH,RPS17,YWHAG,PLEKHF2,KCTD3,VIRMA,ASNSD1,CACYBP,HRAS,WDR6 |
| 4.606e-02 | -3.08 | bone-vertebrae-chordoma | COSMIC cancer mutations | bone-vertebrae-chordoma | 18 | 9 | 16828 | 4835 |
SMARCB1,PTEN,PIK3CA,JAK2,KIT,HRAS,KRAS,CTNNB1,TP53 |
| 4.606e-02 | -3.08 | dysplasia | COSMIC cancer mutations | dysplasia | 18 | 9 | 16828 | 4835 |
PTEN,SF3B1,CTNNB1,KRAS,HRAS,TP53,IDH1,JAK2,IDH2 |
| 4.606e-02 | -3.08 | NS-mesothelioma | COSMIC cancer mutations | NS-mesothelioma | 18 | 9 | 16828 | 4835 |
AKT1,JAK2,KRAS,CTNNB1,KIT,HRAS,MET,PIK3CA,FGFR1 |
| 4.606e-02 | -3.08 | cerebral_cortex | COSMIC cancer mutations | cerebral_cortex | 18 | 9 | 16828 | 4835 |
TP53,KRAS,HRAS,IDH2,SYN3,IDH1,MSH6,EZH2,PTEN |
| 4.614e-02 | -3.08 | regulation of small molecule metabolic process | biological process | GO:0062012 | 331 | 112 | 18204 | 5365 |
TMSB4X,SPHK2,FGF1,JMJD8,NR1H2,PPTC7,MACROH2A1,GNB3,ATP2B4,BAD,IGFBP4,LACC1,TAFAZZIN,NFKB1,PRKCE,RDH10,CRY1,GSK3A,SOX9,KIT,PID1,RGN,SOD1,SLC35B4,DCAF5,CNR1,SNAI2,ATP5IF1,FIS1,TRIM63,MIR675,SIRT7,IGF1,EP300,ADIPOQ,TNF,SLC7A11,GPT,MID1IP1,STAR,AVPR1B,FMO1,AKT1,IL1B,BCKDK,CH25H,SLC45A3,MIR182,STK11,PROX1,ADIPOR1,SELENOS,MIR98,DDIT4,FBP1,CYP27B1,EGR1,MIR204,APOC2,FABP5,ZNF692,CAV1,C1QTNF1,PRKAG1,DKK3,MIR210,ERLIN1,PMAIP1,MIR342,SESN2,IL4,BRCA1,TSPO,ZMPSTE24,GFI1,MIR96,LPCAT3,MIR21,ARPP19,PSEN1,CYP7A1,STARD4,IGFBP3,PPARG,LCMT1,MIR185,DYRK2,TP53,IFNG,ERLIN2,FMO2,DNAJC30,LEPR,BGLAP,MIR107,NUPR1,IER3,CREB1,FLCN,MIR132,LDLR,HTR2A,ENO1,SRC,P2RY1,AKT2,PPARA,INSIG2,KLHL25,LEP,ETFBKMT,GNMT |
| 4.615e-02 | -3.08 | azurophil granule lumen | cellular component | GO:0035578 | 90 | 34 | 19108 | 5553 |
PYGB,ACTR2,FTL,PYCARD,CCT8,GGH,LYZ,CTSA,FABP5,TTR,PSMD1,TOLLIP,HEBP2,PADI2,AGA,PLAC8,TRAPPC1,HEXB,GCA,CTSC,FAF2,CYB5R3,PRDX6,RETN,SERPINA3,GDI2,DSN1,RNASET2,TUBB,SDCBP,DNAJC3,CCT2,TUBB4B,NPC2 |
| 4.617e-02 | -3.08 | Ribosomal_Su5_D2-typ_SF | interpro domains | IPR020568 | 34 | 15 | 18521 | 5414 |
EXOSC4,GFM1,RPS16,HSP90AA1,RPS2,MLH3,TOP2B,MVD,GFM2,EEF2,IMPACT,MRPS9,HSP90AB1,HSP90B1,EXOSC8 |
| 4.617e-02 | -3.08 | mediator complex | cellular component | GO:0016592 | 37 | 16 | 19108 | 5553 |
MED17,MED31,MED10,MED4,NFE2L2,CDK8,MED29,MED22,THRAP3,MED21,MED13L,MED9,MED27,MED23,MED11,MED30 |
| 4.624e-02 | -3.07 | HBB (hemoglobin subunit beta) | protein interactions | 3043 | 176 | 60 | 19454 | 5460 |
EZH2,ZNRF1,SELENOF,SERPINA1,RNF8,B3GNT2,TP53,SERPINA3,GABARAPL1,LPAR6,UBE2V1,TF,GSTT1,RIGI,MSL2,PABPC1,CACUL1,LPAR2,HSD17B10,SEMG2,AGA,HBA1,AGR2,MED4,SCGB1D1,HP,C1QL3,TRAF3IP3,RPL32,H2BC11,SDCBP,HBB,STX17,HBM,HBE1,UBE2M,CFTR,RER1,STAU1,HSDL1,XRCC5,MGAT4B,GLIPR1,UPF3B,ARHGEF6,HSPA8,LCN1,GRID1,UBE2H,AKT1,PDE4B,LGALS3,PGPEP1,MED17,ESR2,DTWD1,SELENOT,EIF4A3,PSMC5,PTEN |
| 4.626e-02 | -3.07 | positive regulation of protein localization to cell periphery | biological process | GO:1904377 | 74 | 29 | 18204 | 5365 |
ATP2C1,SQSTM1,DLG1,ARF6,PRNP,CLIP3,PIAS1,AGR2,AKT1,STAC3,EPHA2,RHOG,PIK3R1,KCNJ11,ZDHHC8,RANGRF,RAMP3,CNPY4,PRKCE,EFCAB7,DPP10,IFNG,LGALS3,ATP2B4,SPTBN1,TNF,RER1,MIR223,PGRMC1 |
| 4.626e-02 | -3.07 | positive regulation of gliogenesis | biological process | GO:0014015 | 74 | 29 | 18204 | 5365 |
TLR2,DAG1,IL1B,RHEB,MIR222,TSPO,TNFRSF1B,PTN,EGR2,VEGFC,IL6ST,UFL1,PRMT5,DICER1,MIR221,CXCR4,MYRF,IL34,ASPA,MECP2,KRAS,TNF,ZNF365,MIR142,NKX6-2,LTA,PTPRZ1,PPP1CC,IL6 |
| 4.632e-02 | -3.07 | liver regeneration | biological process | GO:0097421 | 31 | 14 | 18204 | 5365 |
SRSF1,UCP2,TNF,RGN,IL10,CCND1,PRMT5,GUCD1,PCNA,CLDN1,IL6,TYMS,EZH2,RPS15 |
| 4.632e-02 | -3.07 | multivesicular body assembly | biological process | GO:0036258 | 31 | 14 | 18204 | 5365 |
RAB11A,CHMP1A,VPS4A,CHMP4C,CHMP2B,HGS,VPS4B,CHMP5,CHMP1B,VPS28,UBAP1,TSG101,VTA1,CHMP2A |
| 4.632e-02 | -3.07 | positive regulation of viral genome replication | biological process | GO:0045070 | 31 | 14 | 18204 | 5365 |
CNOT7,PPID,HACD3,TMEM39A,VAPB,CCL5,TOP2B,SRPK2,PDE12,PPIA,PABPC1,CD28,STAU1,PPIH |
| 4.632e-02 | -3.07 | chondroitin sulfate proteoglycan metabolic process | biological process | GO:0050654 | 31 | 14 | 18204 | 5365 |
EXT1,CHPF,BPNT2,CHST9,CSGALNACT2,PXYLP1,CHST13,CYTL1,CHPF2,CHST7,UGDH,CSGALNACT1,CHST11,HEXB |
| 4.632e-02 | -3.07 | positive regulation of adenylate cyclase activity | biological process | GO:0045762 | 31 | 14 | 18204 | 5365 |
TSHR,ADRB3,RAF1,ADORA3,EDNRA,DRD1,STIM1,P2RY11,TMIGD3,CRHR1,RXFP2,LGR4,ADRB2,CAP2 |
| 4.632e-02 | -3.07 | neutrophil activation | biological process | GO:0042119 | 31 | 14 | 18204 | 5365 |
IL15,CCL5,IL18,TYROBP,CXCL8,VAMP2,SYK,FCER1G,MYD88,VAMP8,LILRA2,TRAF3IP2,VAMP7,CAMP |
| 4.634e-02 | -3.07 | Androstenedione Metabolism | SMPDB pathways | SMP0030406 | 16 | 10 | 1369 | 531 |
PDIA2,UGT1A1,CYP11B1,HSD17B3,PPIB,HSPA5,SDF2L1,PDIA6,ERP29,HSD11B1 |
| 4.635e-02 | -3.07 | SLC31A1 (solute carrier family 31 member 1) | protein interactions | 1317 | 189 | 64 | 19454 | 5460 |
CTU1,SLC25A31,ACP2,DTWD1,ST3GAL2,RETSAT,PIK3R3,MRM2,MAP3K21,LGALS8,DTL,RIT1,ATP2C1,HSDL1,LIN7C,BMPR1A,PRIM2,EXD2,SNRK,SLC31A1,IL1RAP,PIK3R2,ARHGEF39,STX7,SLC5A6,PRKAB1,FBXL19,ELP3,CDK7,CSNK1G3,AIFM1,ACSL4,TRAPPC10,HNRNPL,ADCK1,TRAPPC6B,WDR44,PIK3R1,MOV10,FAR2,MZB1,NCR3LG1,NUS1,SMG8,ST3GAL4,NSDHL,DDR1,DLG1,RAB13,USP30,KRAS,ZNF592,PDE2A,SAR1B,RIGI,CYB5R1,MTARC2,CCS,LGR4,DSTYK,PIK3CA,GUCD1,RAB4A,CERK |
| 4.636e-02 | -3.07 | SKP1/BTB/POZ_sf | interpro domains | IPR011333 | 188 | 66 | 18521 | 5414 |
ZBTB26,RCBTB1,KCTD20,KBTBD3,SPOP,KLHL22,ZBTB5,ZBTB25,KCTD10,KCTD17,KBTBD2,KLHL9,IPP,ZBTB16,ZBTB33,KCTD15,RHOBTB3,KBTBD6,CCIN,KCNA3,KCNS1,KLHL12,ENC1,ZBTB14,KLHL7,KCNA2,IVNS1ABP,KCTD16,KCTD11,KLHL3,ZBTB6,ZBTB39,KLHL25,KBTBD13,KCNC1,ZBTB45,NACC2,ZBTB17,KCTD9,KLHL23,RHOBTB1,KCNF1,KLHL32,KCNB1,KBTBD4,SKP1,ZBTB2,KLHL28,BACH1,TNFAIP1,ELOC,KLHL15,ZBTB38,KLHL26,ZBTB18,KCNG3,BCL6,SPOPL,KCND2,ZBTB42,KCND3,KLHL24,KLHL1,KCTD12,KCTD3,BTBD10 |
| 4.637e-02 | -3.07 | regulation of adenylate cyclase activity | biological process | GO:0045761 | 45 | 19 | 18204 | 5365 |
GNAI2,EDNRA,RAF1,ADORA3,GNAI3,TSHR,ADRB3,RXFP2,CRHR1,DRD3,CAP2,LGR4,ADRB2,TMIGD3,CCR2,DRD1,P2RY11,STIM1,GRM2 |
| 4.637e-02 | -3.07 | regulation of protein targeting to mitochondrion | biological process | GO:1903214 | 45 | 19 | 18204 | 5365 |
BNIP3L,UBE2D3,PARL,FBXW7,BAP1,HAX1,UBE2L3,TOMM70,HUWE1,ATP5IF1,TOMM7,GSK3A,UBL5,SH3GLB1,RHOU,HTRA2,LMAN1,PDCD5,RAC2 |
| 4.637e-02 | -3.07 | type I interferon-mediated signaling pathway | biological process | GO:0060337 | 45 | 19 | 18204 | 5365 |
IFIH1,IFNK,IFI27,IFNB1,SIN3A,IRF7,MYD88,MAVS,STAT1,STAT2,JAK1,IFNA13,AZI2,IRF3,IFNAR1,IFNA10,IFNA2,TBK1,TANK |
| 4.637e-02 | -3.07 | response to dexamethasone | biological process | GO:0071548 | 45 | 19 | 18204 | 5365 |
PCK2,SMYD3,EPO,PIK3CA,JAK2,ATP5F1A,UCP2,USP8,CYP1B1,EIF4E,FBXO32,GJB2,FIBIN,DDIT4,HDAC6,IGF1R,CLDN1,PCNA,MSTN |
| 4.637e-02 | -3.07 | PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha) | protein interactions | 8394 | 147 | 51 | 19454 | 5460 |
RPL10,SMURF1,RHOJ,ARF1,CPSF1,PELP1,UBE2H,PFDN2,NRP1,RHOB,LAMTOR1,DNAJC5,RAB2A,FTL,STX7,STAU1,ATPAF2,SNAPC1,RHOU,CSNK1A1,HEXIM1,PRKCA,MIR34B,CAV1,DYNC1I2,GFOD1,RPS16,TMED9,ARF6,HNRNPL,FZR1,RAC2,GJA1,HRAS,RAB35,MIR140,MED4,SNRNP70,H2AC4,DCAF5,RHOG,MOV10,LAMP2,RAD21,PTGES3,KCTD17,KRAS,RABGGTB,SNAPC3,CAPN2,MAP1LC3B |
| 4.640e-02 | -3.07 | GATAD1 (GATA zinc finger domain containing 1) | protein interactions | 57798 | 131 | 46 | 19454 | 5460 |
BRMS1L,SHPRH,KLF9,SIN3A,SRPRA,MYBL2,EED,GATAD1,LDLR,MOV10,SPATS2L,E4F1,RBBP7,PHF1,PAX6,MRFAP1,HAPSTR1,SREK1IP1,EZH2,MTA2,SAP30L,MTA3,ING1,EGR2,NFE2L1,ELF1,SAP30,RBBP4,ESR2,PHF12,ENO1,ELK3,ING2,QSER1,EPHA2,MYC,HNF1B,CSK,MORF4L1,PPP1CC,BRMS1,AR,MBD3,KLF3,RBFOX2,KLF12 |
| 4.648e-02 | -3.07 | C3orf52 (chromosome 3 open reading frame 52) | protein interactions | 79669 | 304 | 99 | 19454 | 5460 |
RAB3A,OSBPL8,BTN2A2,AGPAT1,NUS1,AREL1,DEXI,ST6GALNAC3,DHRS7,CD36,FNDC9,TNFSF18,EXTL2,TMEM45B,SRPRA,AGER,SIGLECL1,TMEM94,PREB,AGPAT5,ALG11,DNAJC30,TNFSF8,RDH11,ATP2B4,BSCL2,SNX14,SMPD2,KCNQ5,MGST2,RETSAT,CREB3,CHST13,CSGALNACT2,FBXO7,DHRS13,MGST3,SEC63,MRGPRX3,SGTA,AMIGO1,STOM,USE1,SLC12A2,LMNA,LEMD3,EPHX1,KCNJ11,TIMMDC1,CHST7,IL1RAP,PML,MGAT4B,LRP10,TMX2,ABCB9,ITPRIPL2,NCR3LG1,RPL23,C2CD2L,ATG9A,TENM3,QPCTL,TOR4A,OSBP,TMEM237,GJA1,ADCY3,TMEM39A,DHRS3,ABHD6,DCAKD,CYB5R1,MYORG,GJB1,ERP29,PIGA,TMEM179B,CYP4F22,KCNJ8,SYNE4,REEP4,REEP3,CYP26A1,LRIF1,CD79B,SLC23A2,FZD6,LRP12,RMDN3,UBAC2,ABCB1,CCL21,BET1,ESAM,ABCC5,FLYWCH2,TMEM168,BMPR1A |
| 4.659e-02 | -3.07 | taxis | biological process | GO:0042330 | 347 | 117 | 18204 | 5365 |
XCL1,IL10,TGFB2,CX3CL1,PLP2,CCR3,DPEP1,CMTM7,RALA,CXCL11,CCL24,CX3CR1,FGF10,CCN3,DEFB1,CXCR1,CCL23,IL1B,SERPIND1,CXCL12,EPHA2,CXCR6,CCR4,CH25H,SYK,FGF7,HMGB1,SEMA3C,ELMO2,CCL20,CXCL1,CREB3,HRAS,CXCR4,S100A8,CCR7,FOLR2,SEMA5A,CCR6,NRP1,CCL28,CCL2,PIP5K1A,CXCL10,DEFB114,CCL4L1,MAP2K1,CCR1,CHGA,CCL18,L1CAM,SLC12A2,KIT,FLRT3,RARRES2,CCL25,CCR5,CCL21,CKLF,MET,RPL13A,CXCR3,NINJ1,CRKL,ADGRE2,RAB13,SFTPD,CCL19,CCR2,LRTM2,DPP4,FCER1G,CXCL8,CCL5,LPAR1,CXCL9,PPIA,SEMA6C,IL6,CCL17,PPIB,ANGPT1,SCG2,RAC2,MIF,CCL3,ITGAV,MSMP,ACKR3,VEGFC,CXCL14,PDE4B,PIK3CG,CCL8,CCL11,MACO1,CCL27,TPBG,SRP54,LGALS3,EFNA5,SEMA7A,VEGFA,RHOG,CCL1,GPNMB,PRKCQ,LECT2,PLGRKT,GAB1,CXCL3,HBEGF,PTN,SEMA4C,CXCL13,JAML,FLRT2 |
| 4.661e-02 | -3.07 | TFIID-class transcription factor complex binding | molecular function | GO:0001094 | 10 | 6 | 18094 | 5411 |
TP53,RUVBL2,ZNHIT6,EDF1,NOP58,RUVBL1 |
| 4.661e-02 | -3.07 | RNA polymerase II CTD heptapeptide repeat kinase activity | molecular function | GO:0008353 | 10 | 6 | 18094 | 5411 |
CDK7,CDK1,CDK8,DYRK1A,CDK12,CDK9 |
| 4.661e-02 | -3.07 | phosphatidylinositol trisphosphate phosphatase activity | molecular function | GO:0034594 | 10 | 6 | 18094 | 5411 |
INPPL1,OCRL,FIG4,INPP5K,PTEN,INPP5E |
| 4.661e-02 | -3.07 | ferric iron binding | molecular function | GO:0008199 | 10 | 6 | 18094 | 5411 |
FTL,FXN,TF,ACP5,FTH1,FTHL17 |
| 4.664e-02 | -3.07 | regulation of organic acid transport | biological process | GO:0032890 | 77 | 30 | 18204 | 5365 |
PPARA,ATP1A2,ARL6IP5,PSEN1,LEP,GRM2,FIS1,SYT4,AKT1,ADORA1,SLC12A2,SLC38A3,IL1B,RGS2,GABBR1,AKT2,SYK,SLC6A1,MIF,CLTRN,PTGES,NPY5R,SLC38A1,AVPR1B,SLC38A2,IL1A,MAP2K6,TNF,STXBP1,SLC43A2 |
| 4.664e-02 | -3.07 | negative regulation of protein ubiquitination | biological process | GO:0031397 | 77 | 30 | 18204 | 5365 |
CHP1,MIR101-1,SVBP,IVNS1ABP,SIRT7,TRIM44,MAD2L2,CAV1,MAD2L1,SPOPL,PPIA,RPS3,CAMLG,TNFAIP3,PRKCE,CRY1,AKT1,BAG2,VPS28,CDK5,MINAR1,GCLC,TSPO,BEX3,RPL23,SQSTM1,UFL1,ISG15,RPS7,PLAA |
| 4.664e-02 | -3.07 | BMP signaling pathway | biological process | GO:0030509 | 77 | 30 | 18204 | 5365 |
SMAD9,SMAD1,BMPR1B,NOTCH2,TWSG1,RGMB,TMEM100,SOSTDC1,EGR1,BMPR1A,FKBP8,PDCD4,BMPR2,SFRP1,SOST,MSX1,DDX5,RGMA,EXT1,SMURF1,HFE,ACVR1,SMAD5,PPARG,NOG,MSX2,USP15,MIR21,CHRDL1,SMAD4 |
| 4.664e-02 | -3.07 | regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0000079 | 77 | 30 | 18204 | 5365 |
CDKN3,CCND1,BCCIP,HEXIM1,CCNB1,PROX1,CDK5R1,CCNA2,CCNH,PSRC1,CDKN1B,RGCC,HEXIM2,GADD45A,MIR711,CCNF,AKT1,CDKN2C,CDKN2D,CDK5RAP3,DIRAS3,MIR15A,CCND3,SERTAD1,CCNI,PTEN,ACTB,CCNY,PSMD10,CDKN1A |
| 4.666e-02 | -3.06 | human chr8q22.3 | chromosome location | human chr8q22.3 | 33 | 12 | 26134 | 5823 |
ANKRD46,BAALC,AZIN1,FZD6,LRP12,ATP6V1C1,YWHAZ,SLC25A32,KLF10,MIR3151,PABPC1,NCALD |
| 4.668e-02 | -3.06 | human chr19p13.11 | chromosome location | human chr19p13.11 | 116 | 34 | 26134 | 5823 |
MIR640,KXD1,SLC25A42,AP1M1,ARMC6,LSM4,OCEL1,HSH2D,PIK3R2,PGPEP1,TMEM59L,BABAM1,ISYNA1,FKBP8,ABHD8,MPV17L2,RAB3A,MAP1S,NR2F6,SSBP4,SLC35E1,KLHL26,UBA52,LPAR2,COPE,CIB3,HOMER3,RFXANK,USE1,MRPL34,BST2,MEF2B,BORCS8,SUGP1 |
| 4.681e-02 | -3.06 | ATF6 (activating transcription factor 6) | protein interactions | 22926 | 112 | 40 | 19454 | 5460 |
RPN1,STIM1,IL7,SSR1,ACAA2,PTRH2,EDDM3B,CDC42,SEC62,DNAJC25,SOX2,ST7,DET1,XBP1,GTF2I,ERLEC1,BPGM,GPIHBP1,FKBP8,TMEM106B,TMT1A,SYVN1,FHL3,DERL1,SP1,COP1,POU5F1,RNF139,TRIB1,NFYA,CSK,HNRNPL,DAPK1,DNAJC1,LDHA,OS9,SEC63,CREB1,LMBR1L,HSD17B11 |
| 4.685e-02 | -3.06 | KLF3 (KLF transcription factor 3) | protein interactions | 51274 | 225 | 75 | 19454 | 5460 |
MTA3,TRAF2,ING1,ELF1,ZMYM3,ZMYM4,TFRC,RPN1,SOBP,OTX2,RING1,FHL3,PCGF3,ZNF609,ZBTB14,RPL28,FOXP4,PCGF6,PDIA3,CALR,TLE1,INO80E,DNTTIP1,NOL4,TPM3,TAF9,LSM3,FOXP1,SSBP1,TFE3,PHB1,ZHX1,GATAD1,TMED9,BRMS1L,DBT,ATP5PD,TOMM70,CTBP1,COX6C,HSP90B1,E2F6,RPL26L1,HIRA,EP300,YAF2,SGF29,KDM1A,PIAS1,CRYZ,SS18,SMARCA5,TAF5L,COX6B1,TADA3,ATP1A1,ZHX3,PHF12,FAU,MIDEAS,VPS72,ATXN1L,LIG3,ING2,QSER1,ZMYM2,TRIM24,UBE2I,PHF21A,IRF2BP1,DYNLL1,GABPA,LRIF1,MORC4,DNPH1 |
| 4.685e-02 | -3.06 | monocarboxylic acid catabolic process | biological process | GO:0072329 | 116 | 43 | 18204 | 5365 |
SESN2,FAH,EHHADH,PCK2,ACAT1,ETFA,NUDT7,ACOT8,HADH,ACOX1,SLC16A1,ILVBL,ETFB,PHYH,CRAT,ABHD2,ECHDC1,SLC25A17,HEXB,AKR1A1,NUDT19,AMACR,PEX13,PLA2G15,CYP26A1,CYP4F12,ADTRP,SORD,LEP,AIG1,PCCB,CRYL1,HSD17B10,HADHA,MCAT,ADIPOQ,DECR2,ACAA2,CPT2,ACADS,AUH,CPT1B,HEXA |
| 4.692e-02 | -3.06 | RARS2 (arginyl-tRNA synthetase 2, mitochondrial) | protein interactions | 57038 | 90 | 33 | 19454 | 5460 |
NPY2R,MGARP,LPAR6,GFM2,PDHA1,AQP3,RPA2,COX8A,VIPR1,EXD2,NSDHL,PREPL,HSPD1,NT5C3A,KRAS,TNFSF8,DDRGK1,TUFM,P2RY10,CUL3,GPBAR1,RIT1,SLC2A1,RHOG,SYP,SLC1A1,GATD3,S100A6,CCNF,SSBP1,EGLN3,RHOH,RHOJ |
| 4.692e-02 | -3.06 | KLHL42 (kelch like family member 42) | protein interactions | 57542 | 90 | 33 | 19454 | 5460 |
DCUN1D1,TRIM54,ADD1,COP1,SSX2IP,SERTAD3,TCEAL9,TRIM23,UBE2E3,MTPN,COPS5,TTC23,GSTM3,CUL3,MSTN,PFDN5,DDI1,COIL,RIGI,ARL6,COPS4,SERTAD1,SEMA4C,OIP5,FAM168A,CYB5D2,EIF1AD,UBE2M,TNNI3K,RNF126,RPA2,TULP3,CSNK1E |
| 4.692e-02 | -3.06 | MIR200C (microRNA 200c) | protein interactions | 406985 | 90 | 33 | 19454 | 5460 |
DDX23,CRTAP,IGF2BP1,DDX1,KARS1,GRSF1,HNRNPA1,TRA2A,NONO,HNRNPL,FAM98A,MATR3,SYNCRIP,CPSF1,EIF2AK2,SF3B4,NUFIP2,HNRNPH3,RARS1,SART3,RBFOX2,STRBP,SF3A1,TRA2B,HNRNPA0,HNRNPF,HNRNPK,G3BP2,MARS1,HNRNPA2B1,SF3B1,HNRNPH2,RTCB |
| 4.692e-02 | -3.06 | PDLIM1 (PDZ and LIM domain 1) | protein interactions | 9124 | 90 | 33 | 19454 | 5460 |
RNF103,CHMP4C,NUDT12,RPA2,SUPT4H1,GABARAPL2,ACTN4,SOX2,RANBP1,B3GNT2,G3BP1,RLIM,NMRAL1,RAB27A,BAP1,SCYL2,RPA3,HSPB1,HNRNPD,PTGER4,BICD2,GORASP2,CUL3,MYC,PGS1,AGK,SNRNP40,RANGRF,SPPL3,IGBP1,FBXO32,FBXO31,CCNF |
| 4.694e-02 | -3.06 | regulation of cyclin-dependent protein kinase activity | biological process | GO:1904029 | 80 | 31 | 18204 | 5365 |
MIR15A,DIRAS3,CCND3,CCNI,SERTAD1,HSP90AB1,CDKN2C,CDKN2D,CDK5RAP3,CDKN1A,PTEN,ACTB,CCNY,PSMD10,CCNB1,PROX1,CCNA2,CDK5R1,CDKN3,CCND1,HEXIM1,BCCIP,RGCC,HEXIM2,GADD45A,MIR711,CCNF,AKT1,CCNH,PSRC1,CDKN1B |
| 4.694e-02 | -3.06 | positive regulation of response to wounding | biological process | GO:1903036 | 80 | 31 | 18204 | 5365 |
THBD,XBP1,PRDX2,STK24,CLDN4,MIR222,ARFGEF1,TMEM97,ST3GAL4,EMILIN1,CLDN3,MIR221,CXCR4,FOXC2,F2,CLDN1,MIR21,HRAS,PTN,PLG,HBEGF,NFE2L2,F7,ENPP4,FKBP1B,FERMT2,PRKCE,CD36,IGF1R,CLEC7A,MIR29A |
| 4.703e-02 | -3.06 | Mitochondrial Electron Transport Chain | SMPDB pathways | SMP0000355 | 12 | 8 | 1369 | 531 |
GPD2,SLC25A4,SDHC,SLC37A4,NDUFA1,UQCRC1,GAPDH,SDHB |
| 4.704e-02 | -3.06 | protein import into nucleus | biological process | GO:0006606 | 113 | 42 | 18204 | 5365 |
SEC13,TRAF3IP2,KPNA6,DRD1,NUP35,IPO8,ING1,NFKBIA,CSE1L,KPNA2,SPRN,STK4,PML,NUP62,CDKN1A,TXNIP,RANBP6,TP53,NUP107,KPNA1,NUP153,PHB2,RPAIN,HIKESHI,NUP50,POLA2,STK3,RPL23,SQSTM1,PPP1R10,TNPO2,LMNA,SYK,RAN,PIK3R1,FAM53B,PPP3CA,TNPO3,FAM53C,RANGRF,AKT1,HSPA8 |
| 4.704e-02 | -3.06 | dendrite development | biological process | GO:0016358 | 113 | 42 | 18204 | 5365 |
SLC25A46,CDK5,PHACTR1,LST1,CTNNA2,NDP,ABITRAM,ELAVL4,PPP3CA,WNT7A,WASL,GHRL,PTN,PICALM,ARF4,DLG4,CRKL,TBC1D24,HDAC6,IQSEC1,PAK2,VLDLR,KLHL1,MAP1S,MECP2,NRP1,ACTL6B,IGF2BP1,GPR37,SLC11A2,TPBG,PTEN,CDC42,ZNF365,TMEM106B,CHRNA7,SDC2,TRAPPC4,MEF2A,RERE,MAP1B,SLITRK5 |
| 4.708e-02 | -3.06 | RNA degradation | KEGG pathways | hsa03018 | 77 | 34 | 7161 | 2463 |
PABPC1,LSM4,EDC3,LSM8,EXOSC4,TOB2,DCP2,NUDT16,PABPC1L,LSM2,DIS3L,BTG2,PABPC5,EXOSC1,LSM3,TENT4A,EXOSC8,CNOT6L,C1D,LSM5,CNOT8,HSPD1,CNOT6,CNOT7,EXOSC3,ZCCHC7,LSM6,MPHOSPH6,BTG1,BTG3,ENO2,CNOT2,ENO1,SKIC8 |
| 4.708e-02 | -3.06 | RNA degradation | KEGG pathways | ko03018 | 77 | 34 | 7161 | 2463 |
ENO1,SKIC8,CNOT2,BTG3,ENO2,MPHOSPH6,LSM6,BTG1,ZCCHC7,EXOSC3,CNOT7,HSPD1,CNOT8,CNOT6,LSM5,CNOT6L,C1D,EXOSC8,TENT4A,EXOSC1,PABPC5,BTG2,LSM3,LSM2,PABPC1L,DIS3L,EXOSC4,TOB2,NUDT16,DCP2,LSM8,PABPC1,LSM4,EDC3 |
| 4.709e-02 | -3.06 | Sorafenib Metabolism Pathway | SMPDB pathways | SMP0000648 | 14 | 9 | 1369 | 531 |
ERP29,CYP2C9,PDIA6,SDF2L1,PPIB,HSPA5,PDIA2,UGT1A1,CYP2C8 |
| 4.723e-02 | -3.05 | NUDIX | prosite domains | PS51462 | 27 | 12 | 12186 | 3388 |
NUDT9,NUDT16,NUDT19,NUDT4,NUDT12,NUDT2,NUDT1,NUDT7,NUDT3,DCP2,NUDT18,NUDT5 |
| 4.734e-02 | -3.05 | liposaccharide metabolic process | biological process | GO:1903509 | 107 | 40 | 18204 | 5365 |
PIGC,GALC,B4GALT4,GPAA1,ST6GALNAC3,B3GALT2,BAX,HEXA,FUT9,PIGW,PIGA,ST3GAL1,UGCG,PGAP2,NEU1,PGAP3,FA2H,PGAP4,HEXB,ST3GAL5,GAL3ST1,LARGE1,B4GALT3,SLC30A5,CERK,PIGK,KIT,ST8SIA5,FUT1,GAL3ST4,ST8SIA4,ST3GAL4,B3GALT1,PIGY,ITGB8,DPM2,B3GALNT1,ST3GAL2,B3GALT4,B4GALT6 |
| 4.739e-02 | -3.05 | pancreas-carcinoid-endocrine_tumour-insulinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-insulinoma | 29 | 13 | 16828 | 4835 |
KIT,MET,CTNNB1,TP53,CDKN2C,FGFR1,PIK3CA,PTEN,NTRK3,HRAS,KRAS,STK11,SMAD4 |
| 4.739e-02 | -3.05 | insulinoma | COSMIC cancer mutations | insulinoma | 29 | 13 | 16828 | 4835 |
CDKN2C,TP53,MET,KIT,CTNNB1,NTRK3,PTEN,PIK3CA,FGFR1,HRAS,KRAS,SMAD4,STK11 |
| 4.741e-02 | -3.05 | KRT16 (keratin 16) | protein interactions | 3868 | 173 | 59 | 19454 | 5460 |
SHC1,CBL,USP15,EMC4,DIRAS2,COPS5,HNRNPA1,HDAC6,GAS8,FZR1,CAND1,PPP1R18,INA,MBD5,CYTH4,EFNA3,TSG101,KRT8,TFCP2,EZH2,HGS,RNF8,FBP1,TP53,SNAPIN,GNG10,TRIM26,NEDD8,POLL,SEMA4C,MEPCE,EWSR1,RC3H2,CCHCR1,UBE2H,MYC,CUL2,CUL3,SMARCE1,TTC23,NDN,VIRMA,ARF1,EIF4A3,AP2M1,UBASH3B,ALB,METTL14,HEXIM1,WTAP,CFTR,SGF29,PIK3R2,PIAS1,MBD3,DDX39B,INPPL1,BANF1,NMRAL1 |
| 4.748e-02 | -3.05 | multicellular organismal response to stress | biological process | GO:0033555 | 89 | 34 | 18204 | 5365 |
USP46,IDO1,HTR1A,MECP2,BRINP1,NR4A2,PTEN,TAC1,ATAT1,GNG7,CRHR1,SLC6A2,UCN,EIF4E,SLC1A1,DRD1,ASIC1,DBH,LARGE1,TACR1,AKT1,VDAC1,EXT1,TSPO,NR2E1,COMT,PPP3CA,ATP1A2,DPP4,SELENON,TMEM74,CAPN2,ADRB1,NEUROD2 |
| 4.748e-02 | -3.05 | negative regulation of protein modification by small protein conjugation or removal | biological process | GO:1903321 | 89 | 34 | 18204 | 5365 |
PLAA,ISG15,RPS7,UFL1,SQSTM1,RPL23,BEX3,TRIM21,HMG20A,TSPO,GCLC,CDK5,MINAR1,BAG2,VPS28,AKT1,PRKCE,CRY1,DCUN1D3,TNFAIP3,CTNNB1,RPS3,CAMLG,PPIA,CAV1,MAD2L1,SPOPL,MAD2L2,IVNS1ABP,TRIM44,SIRT7,MIR101-1,CHP1,SVBP |
| 4.748e-02 | -3.05 | protein targeting to membrane | biological process | GO:0006612 | 89 | 34 | 18204 | 5365 |
SEC62,SRP54,SDCBP,SRPRB,ZDHHC15,SRPRA,ZDHHC14,TRAM1L1,ATG3,ARL6,SEC61G,GOLGA7,RTP4,SRP14,SEC61A2,ZFAND2B,SSR1,SEC63,SSR2,SRP72,ZDHHC4,HSPA5,SEC61A1,TRAM1,SEC61B,GOLGA7B,LARGE1,TRAM2,ADORA1,UBL4A,AQP11,SSR3,SGTA,ZDHHC24 |
| 4.748e-02 | -3.05 | cellular response to amino acid stimulus | biological process | GO:0071230 | 89 | 34 | 18204 | 5365 |
MIR95,MIR545,HNRNPD,SESN3,HPCA,COL1A2,STAMBPL1,LAMTOR2,TNF,RRAGA,BCL2L1,SLC38A9,EP300,RRAGB,GLRA1,MIR455,GLRA2,NTRK2,CAPN2,GRIA1,CUL3,CPEB1,COL3A1,LAMTOR1,GCLC,LAMTOR3,KLHL22,XBP1,AMIGO1,SESN2,MIR421,MIR342,SH3BP4,CASTOR2 |
| 4.751e-02 | -3.05 | SDF4 (stromal cell derived factor 4) | protein interactions | 51150 | 144 | 50 | 19454 | 5460 |
ABCE1,IGF1R,DUSP21,RIGI,SMN1,SLC25A14,B3GNT2,RAF1,TOP3B,MGARP,THOC2,RAP1B,TES,MAPRE2,FAM20C,TUBG1,CHST11,CDKN1B,SMG8,POU5F1,MME,TMEM106B,ACP5,AKAP1,TTR,HSCB,GRPEL1,CLU,HSPA5,CDKN1A,RPA2,PTPN22,FKBP10,ANXA7,NPW,CCNF,ZMYM2,SEC61B,ARMC6,NR1I2,MAD2L2,ESR2,MYC,CUL3,SPOP,YWHAZ,NTRK3,CALU,UBE2H,ILK |
| 4.751e-02 | -3.05 | PARD6B (par-6 family cell polarity regulator beta) | protein interactions | 84612 | 144 | 50 | 19454 | 5460 |
MAP4,YWHAB,AVL9,TSNAX,RASSF8,PSMD10,RHOG,HNRNPA1,ATG7,YWHAG,YWHAH,DPP4,CRB3,HTRA1,TRIM35,HNRNPL,CDCA3,DLGAP4,ARL10,RND3,IFT22,PDHA1,RAF1,MSANTD4,PSMA1,HNRNPF,HECTD3,RUVBL2,PDF,YWHAZ,MCM3,PHKA1,PSMD1,KBTBD6,ESR2,PSMB6,SIAH1,RHOJ,ADRM1,MAGOHB,PTEN,PNMA1,PARD6A,AGGF1,PSMB7,CDC42,WDR83,VPS28,DR1,HSPA8 |
| 4.751e-02 | -3.05 | SMAD9 (SMAD family member 9) | protein interactions | 4093 | 144 | 50 | 19454 | 5460 |
SMAD9,VCPIP1,MED4,DNAJC7,MED29,SNRNP70,SMAD4,E4F1,DKK1,DPY30,DSTN,SMAD3,METAP1,ACVR1,EZH2,PIR,RAF1,MACO1,EIF3E,CSH1,ZNF592,HUWE1,UBE3A,MAN1A2,CLPB,ERVV-1,BCL7B,CXXC5,AP2A1,SMAD2,CHPF,PRMT6,MYC,APEX1,TRIM29,ACTB,MGAT1,PPP2R5E,SMAP2,PELP1,LEMD3,BTG2,LMO4,SPTBN1,UNC45A,FTL,PPP2R2C,KDM1A,SF3B1,TWNK |
| 4.755e-02 | -3.05 | positive regulation of leukocyte chemotaxis | biological process | GO:0002690 | 92 | 35 | 18204 | 5365 |
CCR1,IL6,CX3CR1,VEGFA,SWAP70,IL23A,MSTN,GPSM3,CXCL8,CCL5,F7,CXCL10,CALR,XCL1,TIRAP,IL34,DEFB124,AIF1,CCL19,CCR2,CCR7,OXSR1,CXCL13,CCR6,VEGFC,CREB3,PTN,RAC2,CCL21,CCL3,HMGB1,CCL1,RARRES2,CXCL12,IL12A |
| 4.757e-02 | -3.05 | cellular response to acid chemical | biological process | GO:0071229 | 98 | 37 | 18204 | 5365 |
HPCA,COL1A2,HNRNPD,SESN3,MIR545,VEGFA,MIR95,LAMTOR2,STAMBPL1,EP300,SLC38A9,BCL2L1,RRAGA,TNF,PIK3CA,GLRA2,AQP2,GLRA1,MIR455,RRAGB,CAPN2,NTRK2,LAMTOR3,KLHL22,XBP1,GCLC,LAMTOR1,CPEB1,COL3A1,GRIA1,CUL3,SH3BP4,SESN2,MIR342,MIR421,CASTOR2,AMIGO1 |
| 4.758e-02 | -3.05 | hippocampus development | biological process | GO:0021766 | 95 | 36 | 18204 | 5365 |
CDK5R1,CDK6,PROX1,FEZ1,EMX2,EIF2B5,CRKL,POMT2,UQCRQ,LARGE1,FXR2,CDK5,NEFL,BTG2,RAN,NR2E1,ATAT1,EZH1,NF2,NEUROD6,FGF13,TUBA1A,EZH2,SLC32A1,TMEM108,DRD1,ID4,IGF1R,HTR5A,MKKS,DLX1,MECP2,ATP2B4,PAFAH1B1,PTEN,ATG16L1 |
| 4.763e-02 | -3.04 | regulation of canonical Wnt signaling pathway | biological process | GO:0060828 | 265 | 91 | 18204 | 5365 |
CSNK1A1,CTNNBIP1,TNKS2,PSEN1,SFRP4,JUP,UBE2B,FZD6,DKK3,RUVBL2,RPS12,MAD2L2,TPBG,CAV1,EGR1,TNKS,USP8,WNT10B,PPM1B,CSNK1G3,TMEM196,ZBED3,JADE1,STK3,DDIT3,DAPK3,FRZB,SRC,ATP6AP2,CSNK1E,LYPD6,SOST,SFRP1,MIR1-1,FRMD8,ASPM,GNAQ,LGR4,NLE1,CCNY,G3BP1,RNF146,STK4,RNF14,KPNA1,UBAC2,SNAI2,CSNK1A1L,GSKIP,CTNND1,MIR183,ANKRD6,SOX9,ILK,NFKB1,TMEM88,GSK3A,IGFBP4,ADNP,FOLR1,NHERF1,MIR29C,MIR1260B,SOSTDC1,TMEM170B,SEMA5A,TMEM198,NOG,HECW1,STK11,SDHAF2,GREM1,CCAR2,SMAD4,SOX2,FAM53B,PFDN5,DKK1,PTK7,OTULIN,SIAH2,CTNNB1,MIR145,GID8,TLE1,RUVBL1,LMBR1L,MIR346,SMAD3,SCYL2,RBPJ |
| 4.764e-02 | -3.04 | - | gene3d domains | 3.30.460.90 | 8 | 5 | 14470 | 4137 |
MIEF1,ITPRIPL2,CGAS,MB21D2,MAB21L1 |
| 4.764e-02 | -3.04 | - | gene3d domains | 1.10.287.370 | 8 | 5 | 14470 | 4137 |
PFDN6,PFDN2,PFDN1,PFDN4,PFDN5 |
| 4.764e-02 | -3.04 | - | gene3d domains | 2.20.28.10 | 8 | 5 | 14470 | 4137 |
RCHY1,MCM8,MCM3,MCM6,MCM4 |
| 4.767e-02 | -3.04 | general transcription initiation factor binding | molecular function | GO:0140296 | 53 | 22 | 18094 | 5411 |
GTF2E2,GTF2B,PSMC5,DRAP1,RUVBL1,TP53,GTF2A2,RUVBL2,ATF4,EDF1,JUN,THAP7,DR1,NOP58,GTF2A1,GTF2F1,CAND1,AR,TAF7,BCL10,ZNHIT6,TAF11 |
| 4.779e-02 | -3.04 | BTF3L4 (basic transcription factor 3 like 4) | protein interactions | 91408 | 87 | 32 | 19454 | 5460 |
STAU1,DYNC1I1,NAPG,UNC45A,MRPS18C,RPA3,PRIM2,RPL31,PMAIP1,UBE3A,DR1,ANAPC16,RPA2,HECTD1,OXSR1,ATP5PB,MND1,MED17,DYNC1I2,RPS16,HNRNPL,ZBTB2,ZNF174,METAP1,DOK4,PSPC1,SMAD4,ANKRD49,DNAJC8,NT5C2,BTF3,CSNK2A1 |
| 4.779e-02 | -3.04 | MIR138-2 (microRNA 138-2) | protein interactions | 406930 | 87 | 32 | 19454 | 5460 |
IGF2BP1,DDX1,CRTAP,DDX23,NONO,TRA2A,HNRNPA1,KARS1,APOBEC3B,CSTF3,MATR3,HNRNPL,SF3B4,EIF2AK2,CPSF1,SYNCRIP,HNRNPH3,RARS1,NUFIP2,SF3A1,RBFOX2,MARS1,G3BP2,HNRNPK,HNRNPF,TRIM26,HNRNPA0,TRA2B,RTCB,SF3B1,HNRNPH2,HNRNPA2B1 |
| 4.779e-02 | -3.04 | HTR3C (5-hydroxytryptamine receptor 3C) | protein interactions | 170572 | 87 | 32 | 19454 | 5460 |
LRRC8A,ARL6IP5,MGAT1,GLT8D1,B4GALT1,GJA1,DIPK2A,FAM241B,BPNT2,C1GALT1C1,TMEM30A,TMEM179B,LRFN3,TMED4,SLC38A9,DAG1,EMC8,SEMA4C,TUSC3,RDH11,NSDHL,TMEM87A,TMX2,GPAA1,TMEM59L,POMT2,LEMD3,TMEM39A,TMEM231,NETO2,FUT8,DIPK1A |
| 4.779e-02 | -3.04 | DCTN5 (dynactin subunit 5) | protein interactions | 84516 | 87 | 32 | 19454 | 5460 |
PSME1,DCTN6,ACTR1B,DCTN3,SMC4,KPNA2,KRAS,CAPZA1,PTGES3,MCM6,MEPCE,TBK1,ACTR1A,CAPZA2,DCTN4,CXCL14,PRMT5,PREP,ACTB,DYNLL1,TCP1,TXN,COPE,ESR2,USP5,UQCRH,MED22,TPM3,FATE1,CCT2,MAPRE1,RIT1 |
| 4.779e-02 | -3.04 | EIF4EBP1 (eukaryotic translation initiation factor 4E binding protein 1) | protein interactions | 1978 | 87 | 32 | 19454 | 5460 |
ZNF655,PTPMT1,EIF4E2,EIF3K,SLMAP,CHMP2A,STK3,EIF4A2,RPS27L,CSNK2A1,HNRNPA1,EIF3D,AKT3,LMO2,AKT1,HNRNPAB,CRMP1,DDX1,UBE2H,EIF3G,FBXO11,PICK1,AKT2,KLHL25,EIF4E,IRAK4,EIF3E,EIF4EBP2,MVD,MAPKAPK5,DDIT4L,PRKCA |
| 4.779e-02 | -3.04 | MYH7 (myosin heavy chain 7) | protein interactions | 4625 | 87 | 32 | 19454 | 5460 |
STK3,TAF11,AKAP17A,SPTAN1,PSMD4,SEC61B,CLVS2,GJA1,POLR2L,CHRM5,ATP6V1D,ECD,CCNQ,STK4,ROGDI,BTF3,KLHL9,KXD1,TRIM37,ZSCAN5A,SLC39A3,RNF167,BAP1,DVL2,CCDC69,RBPJ,DISC1,TNNI1,CFTR,TULP3,SNAPIN,TRIM6 |
| 4.779e-02 | -3.04 | RAD17 (RAD17 checkpoint clamp loader component) | protein interactions | 5884 | 87 | 32 | 19454 | 5460 |
RPA2,MACROH2A2,RAD1,PSMC4,RFXANK,H2AX,EMC8,NPTN,CBX7,POLE4,RFC3,RFC2,RPA3,RFC4,LGI1,DCTN3,RIT1,COPS7A,UBXN6,PRMT6,RFC5,TRIM35,TOP1,PRNP,POLE3,S100A6,CRYBB3,GLT8D1,CIB2,EEF1AKMT3,NFKBIB,RAB28 |
| 4.782e-02 | -3.04 | Oncogene Induced Senescence | REACTOME pathways | R-HSA-2559585 | 32 | 15 | 10285 | 3229 |
AGO1,MDM2,MOV10,SP1,ID1,CDKN2D,CDK4,TP53,CDKN2C,UBA52,RPS27A,UBB,TFDP2,TNRC6C,CDK6 |
| 4.782e-02 | -3.04 | Gluconeogenesis | REACTOME pathways | R-HSA-70263 | 32 | 15 | 10285 | 3229 |
ENO1,PC,SLC25A1,ENO2,PGAM1,FBP2,FBP1,SLC25A10,GAPDH,PGK1,SLC25A12,SLC25A11,MDH1,PCK2,PRKACB |
| 4.782e-02 | -3.04 | Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity | REACTOME pathways | R-HSA-399721 | 32 | 15 | 10285 | 3229 |
CAMK2G,PRKCB,GRIA1,PICK1,MDM2,TSPAN7,GRIA2,MYO6,AP2S1,CACNG3,PRKCA,DLG1,AP2A1,AP2M1,DLG4 |
| 4.782e-02 | -3.04 | Trafficking of AMPA receptors | REACTOME pathways | R-HSA-399719 | 32 | 15 | 10285 | 3229 |
DLG4,AP2A1,AP2M1,DLG1,PRKCA,CACNG3,AP2S1,MYO6,GRIA2,PICK1,TSPAN7,MDM2,GRIA1,PRKCB,CAMK2G |
| 4.783e-02 | -3.04 | neuron to neuron synapse | cellular component | GO:0098984 | 365 | 121 | 19108 | 5553 |
PTEN,PDE4B,LRRTM2,C1QL2,YWHAZ,ABHD17A,PDYN,SIPA1L1,RNF10,GRID1,PAK2,FAM81A,PAK6,MTMR2,GRIA2,SLC8A1,NLGN2,CLSTN3,NLGN1,BMPR2,RHEB,RTN4,DLG3,GRIA1,SLC4A8,CACNG3,INPP4A,HOMER3,GNG3,RPS13,RS1,LIN7C,NETO1,RPS3,TIAM1,PKP4,CDK5R1,CPEB1,SYNDIG1,ADD1,PRNP,RGS7BP,RPL10A,INSYN2A,RPS14,NETO2,INSYN1,TMEM108,RPLP0,SEMA4C,HNRNPD,EPS8,BAALC,ZDHHC15,SYN3,PLXNC1,LIN7B,CTNNB1,NTRK2,DLG1,ATP1A3,GRIK1,IQSEC1,EPHA4,SLC39A3,GRM1,CAP2,DROSHA,ROGDI,ADORA1,FLRT3,SIGMAR1,HSPA8,ADD2,EIF3E,SPOCK1,DLG4,ARF1,CHRM1,LRRC4,KPNA1,USP8,BACE1,DGCR8,SLC1A1,IGSF11,TNIK,DISC1,CDK5,RPL7,DRP2,PRRT1,PICK1,CAMK2N1,HOMER1,SH2D5,CHMP2B,SPTBN1,GPHN,CTNND1,RPL12,SLITRK1,LRRC4B,HNRNPH2,DAPK1,NPTN,LRFN3,MAP1B,INSYN2B,C1QL3,ATP1A1,PHB2,RPL8,YWHAH,KCNH1,DNM2,RPL6,C1QL1,P2RY1,FABP5,LRRTM3 |
| 4.785e-02 | -3.04 | GSTK1 (glutathione S-transferase kappa 1) | protein interactions | 373156 | 109 | 39 | 19454 | 5460 |
HSPA8,HAPSTR1,YAF2,SOD1,RPA3,HSPD1,HIRA,FKBP2,HSCB,GUK1,PPIF,PPP2R1A,RAF1,E2F4,CENPM,CCR1,RPA2,RPN1,CHMP4C,OSER1,PDHA1,DSTN,XPO5,GATD3,ESR2,SEC63,WIF1,NUP35,MATR3,CCAR2,TENT5C,ATXN10,PRPF19,GSTK1,COX5A,TST,DCAF11,BAX,CYP1A1 |
| 4.785e-02 | -3.04 | ZNF687 (zinc finger protein 687) | protein interactions | 57592 | 109 | 39 | 19454 | 5460 |
PML,MRFAP1L1,RPA3,DVL2,KCTD17,ASF1A,CDK2AP2,ZNF592,FOXP4,SSRP1,RIGI,FOXP2,NOTCH2,TOP3B,ZNF263,RPL15,ELF1,FAXC,SOX2,H2AX,PNMA2,RPA2,MED23,CCNF,PHF21A,CSNK2B,EED,FBXO22,VIRMA,ZBTB2,SRSF10,ZCCHC10,CDC16,MYC,CSNK2A1,H2AC4,BRD3,LHX2,FOXP1 |
| 4.785e-02 | -3.04 | ZNRF4 (zinc and ring finger 4) | protein interactions | 148066 | 109 | 39 | 19454 | 5460 |
MLF2,DNAJB6,OSBPL8,BTN2A2,NUS1,AREL1,C2CD2L,RNF139,HAX1,CGRRF1,PIGA,UBE2E3,SMPD2,UBE2D1,SNX14,SDF2L1,FZD6,LRP12,UBE2G2,UBE2N,OSBP,CTSB,ST7,CYB5R1,UBA52,UBE2W,NETO2,TMEM39A,LEMD3,EPHX1,SIGMAR1,IDH2,LMNA,EZH2,YIF1A,FBXO11,TMX2,HSPA5,UBE2D3 |
| 4.792e-02 | -3.04 | THSD7A (thrombospondin type 1 domain containing 7A) | protein interactions | 221981 | 24 | 11 | 19454 | 5460 |
ZDHHC15,RPA2,TMUB2,SCN3B,RAD21,RIGI,LHFPL1,SLC16A1,FHL3,RPA3,COMT |
| 4.792e-02 | -3.04 | INSL6 (insulin like 6) | protein interactions | 11172 | 24 | 11 | 19454 | 5460 |
ARMC8,TCEAL9,ZMYND19,HSPA5,RANBP10,RMND5B,MKLN1,GID8,MAEA,GID4,FSTL1 |
| 4.792e-02 | -3.04 | RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1) | protein interactions | 5923 | 24 | 11 | 19454 | 5460 |
YWHAB,NTRK3,SNRNP70,MYC,SRPK2,SRC,USP8,NTRK2,RRAS2,EHD4,HRAS |
| 4.792e-02 | -3.04 | HERPUD2 (HERPUD family member 2) | protein interactions | 64224 | 24 | 11 | 19454 | 5460 |
SLC39A9,TMEM144,SPTSSA,GATAD1,TMBIM6,SYVN1,UBE2B,TMEM31,SLC7A1,TMEM60,EFNA5 |
| 4.792e-02 | -3.04 | CT45A1 (cancer/testis antigen family 45 member A1) | protein interactions | 541466 | 24 | 11 | 19454 | 5460 |
NKAPD1,COPS7A,CKS1B,GAS8,SREK1IP1,NTAQ1,CSNK2A1,FGF12,SDCBP,BCL2A1,RPL22 |
| 4.792e-02 | -3.04 | LNP1 (leukemia NUP98 fusion partner 1) | protein interactions | 348801 | 24 | 11 | 19454 | 5460 |
YWHAG,DDX39A,YWHAH,GAPDH,ANAPC4,YWHAB,NUDT12,YWHAZ,GLUL,CDC20,FZR1 |
| 4.792e-02 | -3.04 | SLC37A3 (solute carrier family 37 member 3) | protein interactions | 84255 | 24 | 11 | 19454 | 5460 |
CAV1,RNASEL,CYB5R3,CSNK1G3,DNAJC19,ZNF177,ARL15,ATRAID,SLC25A46,DAAM1,TOP3B |
| 4.792e-02 | -3.04 | CCL4L1 (C-C motif chemokine ligand 4 like 1) | protein interactions | 388372 | 24 | 11 | 19454 | 5460 |
EMILIN3,CXCL13,B9D1,ACTR1B,DCTN3,DCTN6,EXTL2,DCTN4,NDNF,CCL2,MAP2K1 |
| 4.792e-02 | -3.04 | METTL22 (methyltransferase 22, Kin17 lysine) | protein interactions | 79091 | 24 | 11 | 19454 | 5460 |
HSP90AA1,EXOSC1,ILF2,EXOSC8,GTF3C4,XPO1,HNRNPL,HSP90AB1,HSPA5,KIN,HSPA8 |
| 4.792e-02 | -3.04 | OR1M1 (olfactory receptor family 1 subfamily M member 1) | protein interactions | 125963 | 24 | 11 | 19454 | 5460 |
UFL1,STX5,LRP10,GUCY1B1,BMPR1A,OSBPL8,FGFR1,ZCCHC9,SNX14,EDEM1,DCAKD |
| 4.792e-02 | -3.04 | NANOS2 (nanos C2HC-type zinc finger 2) | protein interactions | 339345 | 24 | 11 | 19454 | 5460 |
CNOT7,S100A10,SIAH1,TNKS2,CNOT6L,TOB2,BTG3,CNOT6,GPBP1L1,CNOT2,CNOT8 |
| 4.792e-02 | -3.04 | GSTZ1 (glutathione S-transferase zeta 1) | protein interactions | 2954 | 24 | 11 | 19454 | 5460 |
HNRNPL,AGR2,TRAF2,CLVS2,PPP1CC,BAG3,PRDX6,GORASP2,SOD1,MYC,KLHL24 |
| 4.792e-02 | -3.04 | KLHL29 (kelch like family member 29) | protein interactions | 114818 | 24 | 11 | 19454 | 5460 |
SFXN2,QPCTL,NUDCD3,STUB1,KLHL9,TRIM32,CEP97,KBTBD6,HSP90AA1,SSR3,HNRNPL |
| 4.792e-02 | -3.04 | B3GALT6 (beta-1,3-galactosyltransferase 6) | protein interactions | 126792 | 24 | 11 | 19454 | 5460 |
VIRMA,UFL1,GRM2,SYNE4,EIF2B5,HADHA,CYP2C18,MCPH1,RAF1,KCNA2,SCN3B |
| 4.792e-02 | -3.04 | SPON1 (spondin 1) | protein interactions | 10418 | 24 | 11 | 19454 | 5460 |
RANBP10,ARMC8,AHCYL1,GID4,MDFI,ZMYND19,GID8,MAEA,CUL3,MKLN1,RMND5B |
| 4.792e-02 | -3.04 | IRGM (immunity related GTPase M) | protein interactions | 345611 | 24 | 11 | 19454 | 5460 |
SQSTM1,TAX1BP1,CGAS,RIGI,PYCARD,ATG16L1,CFL1,BECN1,TLR3,NLRP3,SH3GLB1 |
| 4.792e-02 | -3.04 | AACS (acetoacetyl-CoA synthetase) | protein interactions | 65985 | 24 | 11 | 19454 | 5460 |
RPA2,STAT6,CASP4,CLIC4,SEPHS1,CMTR2,RPA3,EEF1AKMT3,TSG101,ARFIP1,CYP2C18 |
| 4.792e-02 | -3.04 | COQ7 (coenzyme Q7, hydroxylase) | protein interactions | 10229 | 24 | 11 | 19454 | 5460 |
COQ8B,PMPCA,GLRX5,BOLA3,COQ8A,ATP5F1E,PTPMT1,CHCHD2,IDE,APEX1,POLDIP2 |
| 4.792e-02 | -3.04 | COX4I2 (cytochrome c oxidase subunit 4I2) | protein interactions | 84701 | 24 | 11 | 19454 | 5460 |
KRAS,UQCRQ,SACM1L,ATP1A3,COX6C,PIGA,DCUN1D5,COX6B1,COX5A,COX4I2,H2BC9 |
| 4.792e-02 | -3.04 | positive regulation of stem cell population maintenance | biological process | GO:1902459 | 48 | 20 | 18204 | 5365 |
LBH,BRD9,RBBP7,SIN3A,BCL7B,ACTL6A,ACTB,ACTL6B,SAP30,ZNF322,SMARCB1,BRMS1,BRMS1L,SS18,SAP30L,RBBP4,ING1,ING2,BCL7C,SMARCE1 |
| 4.792e-02 | -3.04 | nucleotide transport | biological process | GO:0006862 | 48 | 20 | 18204 | 5365 |
ABCC5,CD47,SLC35B3,CALHM3,SLC25A32,SLC25A42,SLC25A24,SLC25A4,LRRC8C,LRRC8B,GJB1,SLC25A23,SHOC2,ANKH,SLC25A51,SLC25A17,SLC25A5,LRRC8A,SLC25A31,LRRC8D |
| 4.802e-02 | -3.04 | molecular function regulator activity | molecular function | GO:0098772 | 2079 | 655 | 18094 | 5411 |
TOM1L1,IL23A,SH3BP5L,PSME1,GNAZ,CCL27,NDP,SERPINB10,USP14,CAV3,ARHGAP19,RAB4A,RBCK1,CFTR,ADM2,GH1,RHEB,IFNG,DNAJC7,CCL3,STX8,RACGAP1,PKIB,MSTN,SPOP,GSKIP,ID4,RERG,UTS2,BAD,NEK7,ARHGEF6,CDNF,CXCL12,PI3,ACAP2,FZR1,CYTH2,RANBP1,CACNB3,ARHGAP15,LEP,RALB,XCL1,FLRT3,KCNMB1,ELMO1,EIF2B2,GNA11,RASGRP2,PIK3R1,FXYD6,GSTP1,TFPI,CDKN2D,TBC1D17,IL21,ERRFI1,RAP2C,TNFSF10,PROS1,RGS2,IL15,KCNAB1,CDK5R1,HTRA1,GTF3C4,CCL17,AZIN2,NUPR1,PPP2R3A,SLPI,FAM3C,BAG3,FGF16,TAB1,SEMA3C,ARHGAP12,FKBP1B,CCNA2,PRKCB,PDP2,IL17F,PLAA,PRKCE,CCL4L1,PPP1R10,CSNK2B,LYPD6,RPS20,BST2,LXN,PPP1R27,RHOU,BIRC2,RAB11A,DNAJC3,PAK2,CTSA,MDFI,DELE1,NLRP1,WNT10B,WNT7A,EFNA5,SPRED2,CDKN1B,GTF2H4,ARHGAP25,MIF,TMBIM6,IL12B,LTA,CHN2,MT3,FBXO8,BGLAP,TBC1D16,CCND3,HEXIM1,SERPINC1,NOS1AP,SPP1,SLC38A9,IL18BP,KRIT1,PPP2R5A,GPSM3,CMTM7,SEC23A,FGF22,RASL10B,SEMA7A,CTSK,PDE4B,RPS7,CCNQ,ARF6,MAT2B,LRP6,SVBP,CD40LG,CCL21,SOCS3,PPP1R16A,KRAS,IFNA13,VIP,TESC,PCP2,PDE8A,ADRM1,ARFGAP3,CAMK2N1,CXCL11,SCN1B,TBC1D1,AKT2,LAMTOR1,PI16,LYAR,HSCB,ARFGEF1,CXCL13,SNIP1,ENHO,CAV1,JUN,HTR2A,CCL20,PRKAG1,SNTA1,SPINT2,RGS5,TBC1D19,ATP2B4,IQSEC1,APH1A,OAZ1,CCL24,CDK4,GREM2,RGS6,PSME2,BEX3,GPHA2,LYNX1,PPY,LACRT,SH3BP4,RAP1A,THG1L,LAMTOR3,IL2,IL34,GNAQ,LHB,RETN,CCL8,FGF7,PCSK9,PACSIN3,ESR2,CSF2,IL1B,CHP1,SWAP70,NKX3-1,TNFSF18,CCL2,DLG1,GREM1,RAB5A,RASL12,GHRL,BCL10,PSMD3,RAC2,DNAJB4,DKK3,FAF1,RHOH,RGL2,ARHGAP5,COX6A2,LTB,GAPDH,C9orf72,CKS2,SRI,SOST,CYB5B,RGS10,HRAS,FKBP1A,GRM2,STK3,NBN,RING1,HEXIM2,PDCD5,CARTPT,TGFBR2,TXNIP,TNFAIP8,TRIM23,HSPB2,BMP1,AKT1,TANK,CAB39,TGFB3,DNAJC2,PCNA,FAF2,IL3,EED,RAN,P2RY12,RAB1B,TIMP3,PIK3R3,NPY2R,SOCS4,PEBP1,EPO,ARF4,EIF2AK2,CKLF,KCNIP2,NEK9,OCRL,PTN,MNAT1,SEMA5A,MSMP,DPEP1,RASL10A,CXCL1,FBXW7,PHACTR1,HACD3,STOM,DNAJC19,RPLP1,DNAJC24,FGF1,WNT2,NFKBIA,CSTA,ELFN2,SERPINB1,IL6,RPS15,PREB,ROCK1,GNRH1,BAG2,CLPX,SDHAF4,F2,DKK1,ZNF451,ARPP19,NKRF,RANGRF,CCL18,ARFGAP1,IL18,ANXA4,SLA2,FGD2,CCNH,PPP1R17,PPP1R8,ING2,FURIN,YWHAG,CDKN2C,RGP1,HYAL2,CAMK2N2,CLEC12B,EIF2B3,FASLG,CD80,SLCO1B3,SERPINB6,RCVRN,TNFSF15,SESN2,VAV2,VSIR,STARD13,TBC1D4,TNFSF8,AFAP1L2,PSMD14,CX3CL1,CSH1,PIK3R2,ABHD5,AHSA1,INHA,TNFSF13,YWHAH,IGFBP3,MRLN,UBE2N,IL4,MTRNR2L7,PSENEN,RGCC,NTF4,AGAP2,CNPPD1,CCL19,RAPGEF5,CDC42SE1,RAB11B,CRISP1,LAMTOR2,DNAJB2,CD86,DNAJC1,IFNK,STX1A,CCL23,IGF1,REG1A,CYTH4,MTRNR2L3,IL13,CDC20,FGF23,LY6H,PSD2,VEGFC,STK4,PLN,PPP1R11,TRIB1,CER1,DEFB114,NLRP3,ALOX5AP,SAR1B,TOPBP1,GNRH2,SERPINA1,PPP1R2,APLN,CTSC,FGF10,CCL5,PDE6D,CKS1B,ELMOD1,SCN3B,TGFB2,MACROH2A1,PPP3R2,UGT1A1,DDIT3,RGL1,PTTG1,DMPK,SCN2B,MLN,PI15,OPHN1,CCNF,HMGA1,FLCN,CCNB1,RPS27L,SOCS2,ARHGAP1,VEGFA,SKP1,PLCB1,PPP1R12A,HBEGF,HSP90AB1,NGB,SPINK13,BCCIP,RP2,CXCL8,NHERF1,TIMP4,RAMAC,GRPEL1,CDK5,PKIA,LAMP2,RASL11A,AHCYL1,PNOC,SIN3A,TIAM1,OAZ2,PPP1R1A,DENND6B,IL1A,IFNA2,UBE2L3,SNCB,THY1,ID1,TMEM168,CST11,SERPINB11,HMGB1,TTR,RALGAPA2,DNAJC10,SST,RASGEF1C,RAP2B,FGF13,CCN3,RABIF,ATP1B1,STRADB,ARL2BP,MOB3C,NFKBIL1,CISH,PPP1R26,CHRNA7,APOC2,SPRED1,IFNB1,CCL1,CCL28,SHOC2,RIT2,OGN,RGN,PKIG,SCLT1,CXCL14,DPP4,VAMP8,RLN2,SUMO1,SERPINA5,SIPA1L1,VTI1B,SPOCK1,CCAR2,WFDC5,SEC61B,SEMA6C,TRMT112,RASGRP3,XRCC5,CDKN1A,PATE4,STX7,HSP90AA1,AGAP1,RAB1A,DNAJB6,CXCL3,MAP2K1,CDC42,ERAS,RIT1,ATP5IF1,TBC1D10C,SERPINA3,MAP3K12,SMAP2,DYNLL1,WFDC13,SERPINI1,ADIPOQ,SERPINH1,IL10,HSPB1,PRKRA,AZIN1,STK11,STC1,TOR1AIP2,HCRT,BIRC5,SPINK9,PSMD1,SEMA4C,SRC,GPIHBP1,KCNMB2,NRP1,FGF3,GTF2F1,MOB3B,GDPGP1,PYCARD,SCG5,PRNP,CXCL10,DAD1,CXCL9,RLN3,NCK1,CALML5,CST3,OAZ3,TBC1D5,IL12A,EPHA2,PPP2R5E,ATP1B3,ALKAL1,RAP2A,IL7,SOS2,YWHAB,RALA,ELP3,ABCE1,TIMP1,CCL11,IFNA10,USP6NL,IL22,PPP1R1B,RAB5C,UCN,PPME1,CCNY,CDC42EP2,COX17,PRDX3,GLRX,FGF17,FGF12,ELFN1,AMELX,DUSP19,NPPC,CYTH1,STIM1,CWF19L1,RTKN,SFN,SCG2,RAB27A,IGBP1,PRL,PPP2R2C,CCNI,RPL23,TCF23,LCN1,PRRT1,LGALS3,FLRT2,DPM2,TNFSF12,WDR6,DEPDC1B,GRPEL2,MET,KCNS1,PIK3CA,PTHLH,IL6ST,ADRB2,OSM,PPP2R1A,LILRB4,CCL25,EIF2B5,FAM13B,DENND2D,DFFA,MGST2,TAFA1,EEF1B2,NPY,CCND1,GIT2,STAP1,IL5,OSGIN2,RGS1,DPP10,TBC1D24,AMIGO1,RAP1B,SERPIND1,TP53,PDYN,PROK1,CACNG3,TBC1D13,WDR20,GDI2,ARHGAP21,TNF,WASL,MRAS,PRPSAP1,SOCS5,GPNMB,TBC1D25,SERPINB9,ARHGEF39,KCNIP3,CSTB,ELMOD2 |
| 4.805e-02 | -3.04 | alcohol metabolic process | biological process | GO:0006066 | 322 | 109 | 18204 | 5365 |
CYP39A1,ACAA2,LEPR,ERLIN2,IDH3A,SPR,NUDT4,CYP27A1,LEP,IDH2,INSIG2,DHRS3,SORD,GPD2,GDE1,SULT1B1,IP6K1,ADH1B,IMPA2,PIP4P1,ACO2,INPP4A,SPTSSB,RETSAT,ERRFI1,LDLR,ISYNA1,FGFR1,NUS1,IDH3B,HMGCS1,CYP2C18,ERLIN1,MECP2,AKR7A2,PNPLA4,CYP27B1,AKR1C1,SNX17,AKR1C2,MOXD1,PTS,CLN8,SC5D,SRD5A3,PLPP6,OCRL,LIPA,DHRS4,NSDHL,CYP7A1,TKTL1,IL4,ADH1A,CYP2D6,ALG2,PCK2,PLCB1,STAR,NPC2,DBH,RDH12,CYP2R1,GK5,NPC1L1,DHRS7,PCBD1,CYP11B2,CYB5R3,IGF1,FKRP,DPAGT1,LBR,SULT1A3,HSD17B6,MPDU1,DPM2,AKR1B1,MSMO1,RDH11,GK2,GDPD3,CYP3A5,CH25H,IDH1,FDFT1,CYP11B1,NUDT3,SPTSSA,ACER3,THTPA,RDH10,NFE2L1,AKR1A1,SDR16C5,PCSK9,VLDLR,CYP2C9,LRAT,SPHK2,CBR4,CYP2C8,MVD,CYP1A1,ALDH1A3,CYP1B1,G6PD,DOLK,CFTR |
| 4.812e-02 | -3.03 | core mediator complex | cellular component | GO:0070847 | 26 | 12 | 19108 | 5553 |
MED10,MED31,MED22,MED17,MED21,MED4,MED29,MED23,MED27,MED9,MED11,MED30 |
| 4.816e-02 | -3.03 | Inflammatory Response Pathway | WikiPathways | WP453 | 33 | 17 | 5310 | 1910 |
IL4,IL2RB,IFNG,COL1A2,CD86,IL5,COL3A1,CD28,CD80,IL2RA,CD40,LAMB2,IL2RG,THBS3,CD40LG,TNFRSF1B,IL2 |
| 4.822e-02 | -3.03 | PPP6R1 (protein phosphatase 6 regulatory subunit 1) | protein interactions | 22870 | 157 | 54 | 19454 | 5460 |
PIH1D1,BORCS6,GTF3C4,AGO1,ATG16L1,SKP1,KDM1A,HADHA,HSPA8,RPA3,UBE2H,DNAJC19,PFDN6,PFDN2,BRCA1,MYO6,CUL3,GPR17,ESR2,DYRK1A,PHF21A,FAM43A,GSK3A,CHRM4,CCNF,DCLRE1C,LMBR1L,S1PR4,MOB3C,HDAC11,DNAJC2,DISC1,DNAJC25,SOX2,MGARP,CLEC2B,CHRM3,COMTD1,TBK1,TOP3B,RIGI,SRPRB,PRPSAP1,SLC25A11,MAP3K14,P2RY10,XPO1,PFDN5,ILVBL,EGLN3,DNAJC1,KRT8,RCHY1,SRPRA |
| 4.823e-02 | -3.03 | ZFPL1 (zinc finger protein like 1) | protein interactions | 7542 | 438 | 139 | 19454 | 5460 |
ATP1A1,MFSD14B,EPHA2,TMEM106C,ARFGAP3,DEPDC1B,ARHGAP21,GORASP2,RAB2A,FERMT2,MGST3,YES1,PPP2R5E,GAB1,VAMP3,ELOVL4,NECTIN2,VPS54,LEMD3,JUP,SLC12A2,STOM,PICALM,GOLGA5,RABL3,SPTBN1,ARHGAP1,UBA52,NF2,YKT6,MAVS,ARFIP1,ITM2B,OSBPL8,TIAM1,CD81,RELL1,PLEKHO1,SLC38A2,LMAN1,CAV1,COG1,FCHO2,FNDC9,SLC39A10,ADD1,CDCA3,HRAS,PTPN1,EHBP1,SSMEM1,TFRC,TMEM31,EXOC3,DISC1,RELL2,UBIAD1,SLC29A1,CCDC47,SNAP29,SLC6A8,CTNND1,RIGI,ADD2,FKBP8,AKAP12,SLC7A14,SGMS2,MRPS18B,SEPTIN7,CYBRD1,SNAP23,PALM2AKAP2,FAF1,CLEC7A,DLG1,SLC38A1,SCFD1,FAM219A,GCC1,CGRRF1,LMNB1,SLC30A5,NIBAN2,TM4SF19,PKP4,SCN3B,ESR2,MB21D2,RANBP6,SYNE4,FAM83B,LMBR1L,FAM91A1,ARF1,ARCN1,TMEM115,VAPB,OTULINL,USP6NL,MTMR6,BET1,NOTCH2,STX7,GOSR1,HSPA8,BET1L,AKAP1,CXCR4,EXD2,STX1A,C2CD2L,SLC20A1,PPFIBP1,FATE1,LAMP2,RAB5C,EGLN3,TMEM237,OCRL,SPTAN1,NEO1,GJA1,SLC19A3,STX5,WDR6,PLAC9,TMEM14B,HGS,VAMP2,BZW2,TULP3,AHCYL1,KRAS,SLC20A2,EFNB1,MYO1B,TMEM87A,SCYL2 |
| 4.834e-02 | -3.03 | substrate-dependent cell migration | biological process | GO:0006929 | 23 | 11 | 18204 | 5365 |
SDCBP,CD2AP,SNAI2,P2RY12,OPHN1,ATP5F1B,NRP1,VEGFC,CTTN,ITGA2,NCK1 |
| 4.834e-02 | -3.03 | pyrimidine ribonucleotide biosynthetic process | biological process | GO:0009220 | 23 | 11 | 18204 | 5365 |
NME2,AK5,NME4,UPRT,DCK,CMPK1,UMPS,UCK2,NME1,UCKL1,UCK1 |
| 4.834e-02 | -3.03 | G protein-coupled serotonin receptor signaling pathway | biological process | GO:0098664 | 23 | 11 | 18204 | 5365 |
HTR2A,HTR5A,HTR1A,HTR1F,HRH2,CHRM5,HRH3,CHRM1,CHRM3,CHRM4,GNAZ |
| 4.834e-02 | -3.03 | negative regulation of organic acid transport | biological process | GO:0032891 | 23 | 11 | 18204 | 5365 |
GABBR1,AKT2,SLC43A2,TNF,ADORA1,AKT1,RGS2,FIS1,NPY5R,LEP,ARL6IP5 |
| 4.834e-02 | -3.03 | positive regulation of glycoprotein biosynthetic process | biological process | GO:0010560 | 23 | 11 | 18204 | 5365 |
CCR7,IL15,CCL21,NCSTN,CCL19,IGF1,POMT2,PLCB1,CTNNB1,PXYLP1,CHP1 |
| 4.834e-02 | -3.03 | pyrimidine nucleoside triphosphate metabolic process | biological process | GO:0009147 | 23 | 11 | 18204 | 5365 |
UCK2,UCKL1,DTYMK,UCK1,ENTPD4,DCTPP1,TYMS,AK3,NME1,NME4,NME2 |
| 4.834e-02 | -3.03 | melanosome localization | biological process | GO:0032400 | 23 | 11 | 18204 | 5365 |
VPS33A,BBS5,RAB11B,ARL6,MKKS,BLOC1S3,RAB1A,MREG,BLOC1S5,RAB11A,RAB27A |
| 4.834e-02 | -3.03 | signal transduction involved in regulation of gene expression | biological process | GO:0023019 | 23 | 11 | 18204 | 5365 |
SMAD3,SMAD2,CER1,EPCAM,TRAF3IP2,P2RY1,TRAF2,PAX6,IRF3,MSX2,MSX1 |
| 4.843e-02 | -3.03 | ubiquitin-like protein conjugating enzyme activity | molecular function | GO:0061650 | 39 | 17 | 18094 | 5411 |
UBE2K,UBE2B,UBE2A,UBE2L3,UBE2I,UBE2F,UBE2M,ATG3,UBE2W,UBE2H,UBE2G2,UBE2N,UBE2D3,UBE2E2,UBE2S,UBE2E3,UBE2D1 |
| 4.843e-02 | -3.03 | ADP binding | molecular function | GO:0043531 | 39 | 17 | 18094 | 5411 |
CHORDC1,MYO6,PRKAG1,PPP5C,ATP5F1D,MSH6,ATP5F1A,CYB5R3,GCLC,MIEF1,HSPA8,P2RY1,RUVBL1,RUVBL2,NLRP3,COQ8A,PGK1 |
| 4.862e-02 | -3.02 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_III | 8 | 5 | 16828 | 4835 |
KRAS,TP53,IDH1,PTEN,IDH2 |
| 4.862e-02 | -3.02 | lichen_sclerosus | COSMIC cancer mutations | lichen_sclerosus | 8 | 5 | 16828 | 4835 |
HRAS,KRAS,TP53,IDH1,IDH2 |
| 4.862e-02 | -3.02 | cranium | COSMIC cancer mutations | cranium | 8 | 5 | 16828 | 4835 |
PIK3CA,TP53,AKT1,EWSR1,PTEN |
| 4.862e-02 | -3.02 | bone-chondrosarcoma-conventional | COSMIC cancer mutations | bone-chondrosarcoma-conventional | 8 | 5 | 16828 | 4835 |
IDH2,IDH1,EWSR1,TERT,PIK3CA |
| 4.862e-02 | -3.02 | paranasal_sinus | COSMIC cancer mutations | paranasal_sinus | 8 | 5 | 16828 | 4835 |
PTEN,KRAS,HRAS,KIT,PIK3CA |
| 4.862e-02 | -3.02 | meninges-malignant_melanoma | COSMIC cancer mutations | meninges-malignant_melanoma | 8 | 5 | 16828 | 4835 |
TP53,HRAS,KIT,GNA11,GNAQ |
| 4.862e-02 | -3.02 | endometrium-hyperplasia | COSMIC cancer mutations | endometrium-hyperplasia | 8 | 5 | 16828 | 4835 |
KRAS,HRAS,TP53,PIK3CA,PTEN |
| 4.862e-02 | -3.02 | endometrium-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-small_cell_carcinoma | 8 | 5 | 16828 | 4835 |
PTEN,KRAS,CTNNB1,KIT,HRAS |
| 4.862e-02 | -3.02 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_II | 8 | 5 | 16828 | 4835 |
IDH2,IDH1,PTEN,TP53,KRAS |
| 4.862e-02 | -3.02 | papillary_adenocarcinoma | COSMIC cancer mutations | papillary_adenocarcinoma | 8 | 5 | 16828 | 4835 |
NTRK3,MSH6,TP53,KRAS,HRAS |
| 4.862e-02 | -3.02 | thyroid-carcinoma-insular_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-insular_carcinoma | 8 | 5 | 16828 | 4835 |
PTPN11,HRAS,KRAS,TFG,TSHR |
| 4.862e-02 | -3.02 | penis-carcinoma | COSMIC cancer mutations | penis-carcinoma | 8 | 5 | 16828 | 4835 |
PIK3CA,TP53,HRAS,KRAS,PTEN |
| 4.862e-02 | -3.02 | skin-chest-malignant_melanoma-nodular | COSMIC cancer mutations | skin-chest-malignant_melanoma-nodular | 8 | 5 | 16828 | 4835 |
HRAS,KIT,CTNNB1,IDH2,IDH1 |
| 4.862e-02 | -3.02 | insular_carcinoma | COSMIC cancer mutations | insular_carcinoma | 8 | 5 | 16828 | 4835 |
TFG,TSHR,HRAS,KRAS,PTPN11 |
| 4.862e-02 | -3.02 | eye-malignant_melanoma | COSMIC cancer mutations | eye-malignant_melanoma | 8 | 5 | 16828 | 4835 |
PTEN,EWSR1,GNAQ,CTNNB1,TERT |
| 4.862e-02 | -3.02 | upper_aerodigestive_tract-trachea-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-trachea-carcinoma-adenoid_cystic_carcinoma | 8 | 5 | 16828 | 4835 |
KIT,HRAS,KRAS,PIK3CA,PTEN |
| 4.862e-02 | -3.02 | vulva-other-lichen_sclerosus | COSMIC cancer mutations | vulva-other-lichen_sclerosus | 8 | 5 | 16828 | 4835 |
TP53,HRAS,KRAS,IDH2,IDH1 |
| 4.862e-02 | -3.02 | stomach-carcinoma-papillary_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-papillary_adenocarcinoma | 8 | 5 | 16828 | 4835 |
TP53,KRAS,HRAS,NTRK3,MSH6 |
| 4.862e-02 | -3.02 | haematopoietic_and_lymphoid_tissue-other-normal | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-other-normal | 8 | 5 | 16828 | 4835 |
IDH1,JAK2,KRAS,HRAS,KIT |
| 4.862e-02 | -3.02 | FAHD1 (fumarylacetoacetate hydrolase domain containing 1) | protein interactions | 81889 | 170 | 58 | 19454 | 5460 |
PIR,NDUFS6,GFM2,NDUFA2,MRPL47,METTL15,GUK1,CHDH,FASTKD5,PREPL,HSPD1,THNSL1,BCKDK,COA4,PC,AK2,MRPL18,TRMT5,BRD3,CLPX,MMUT,MRPL9,DBT,MACROD1,MRPL24,HDHD5,MGME1,NUDT9,MRPS18A,QRSL1,IDH2,COQ8B,DHRS4,HSCB,MRPL40,MRPL57,MRPL41,MRPL20,SELENOO,PTRHD1,MME,RPA3,EXD2,EXOSC4,SORD,MTG2,LDHB,MRM2,CFL1,MRPL16,AK3,LDHA,CPT2,TENT5C,NDUFAF4,INHA,CAB39,MRPL13 |
| 4.865e-02 | -3.02 | MIR107 (microRNA 107) | protein interactions | 406901 | 84 | 31 | 19454 | 5460 |
DDX1,IGF2BP1,KARS1,RBM17,HNRNPA1,NONO,TRA2A,HNRNPL,FAM98A,MATR3,CDC5L,SYNCRIP,CPSF1,EIF2AK2,SF3B4,P3H1,NUFIP2,RARS1,HNRNPH3,RBFOX2,SF3A1,HNRNPA0,TRA2B,HNRNPF,HNRNPK,MARS1,G3BP2,HNRNPA2B1,SF3B1,HNRNPH2,RTCB |
| 4.865e-02 | -3.02 | SPATA2 (spermatogenesis associated 2) | protein interactions | 9825 | 84 | 31 | 19454 | 5460 |
SSNA1,RBCK1,TRIM37,TNF,EFHC1,DLG1,GARRE1,LIN7C,OTULIN,CASK,TRAF2,CRAT,FGL2,TNRC6C,VIRMA,CNTROB,SNX2,TAB1,TRIM27,ARL10,MID1IP1,ETV6,PFDN6,PFDN4,YWHAZ,IKBKB,TUBG1,SPATA2,XPO1,CUL3,BABAM1 |
| 4.865e-02 | -3.02 | MIR16-2 (microRNA 16-2) | protein interactions | 406951 | 84 | 31 | 19454 | 5460 |
DDX1,IGF2BP1,CRTAP,HNRNPA1,NONO,TRA2A,APOBEC3B,KARS1,FAM98A,HNRNPL,MATR3,SF3B4,SYNCRIP,CPSF1,EIF2AK2,RARS1,HNRNPH3,RBMS2,RBFOX2,STRBP,MARS1,G3BP2,HNRNPA0,TRA2B,HNRNPF,HNRNPK,ZC3H7A,HNRNPH2,SF3B1,RTCB,HNRNPA2B1 |
| 4.865e-02 | -3.02 | MIR9-1 (microRNA 9-1) | protein interactions | 407046 | 84 | 31 | 19454 | 5460 |
MATR3,FAM98A,HNRNPL,TENT2,EIF2AK2,MYEF2,SYNCRIP,SF3B4,CRTAP,DDX1,IGF2BP1,GRSF1,KARS1,APOBEC3B,NONO,TRA2A,HNRNPA1,HNRNPK,HNRNPF,TRA2B,HNRNPA0,MARS1,HNRNPA2B1,RTCB,SF3B1,HNRNPH2,ZC3H11A,RARS1,HNRNPH3,STRBP,RBFOX2 |
| 4.865e-02 | -3.02 | IQSEC1 (IQ motif and Sec7 domain ArfGEF 1) | protein interactions | 9922 | 84 | 31 | 19454 | 5460 |
IRF7,P4HA2,SQSTM1,DDX39B,GNAQ,MLLT6,INSYN2A,RAF1,BRINP1,EGLN3,VIRMA,ARF6,SRPRA,CRYBB3,CCNF,LURAP1,EEF1AKMT3,FBLN5,CTNNA1,DNAJC7,DNAJB6,FAM83A,PELI3,RHOB,RC3H2,YWHAG,XPO1,HSPB8,ACTL6B,MYC,PRMT6 |
| 4.868e-02 | -3.02 | NUDCD3 (NudC domain containing 3) | protein interactions | 23386 | 141 | 49 | 19454 | 5460 |
ACTR1A,MTCH2,KBTBD4,KLHL12,KLHL26,FAM136A,ACTR2,ENC1,GLE1,KLHL15,KLHL23,NAE1,CCIN,KLHL22,KLHL9,RHOG,SSBP1,SLC25A12,LMAN1,DIRAS3,PRNP,DYNC1I2,HNRNPL,DCUN1D1,DET1,PAFAH1B1,KLHL3,SAMM50,AKAP1,KLHL28,HSPA8,HCFC2,PXMP2,RADX,KDM1A,CUL3,KLHDC8A,HSP90AA1,KLHL1,SPOP,LAMTOR1,UBE2I,ANAPC2,KBTBD6,VIRMA,DYNLT3,DYNLL1,TUBB,SNRNP40 |
| 4.871e-02 | -3.02 | Activation of GABAB receptors | REACTOME pathways | R-HSA-991365 | 40 | 18 | 10285 | 3229 |
GABBR1,GNB1,ADCY2,KCNJ2,GNAI3,GNG3,GNG5,KCNJ3,GNG10,GNG7,GNAI2,GNG12,ADCY3,KCNJ10,GNG2,MIR197,GNGT2,GNB3 |
| 4.871e-02 | -3.02 | GABA B receptor activation | REACTOME pathways | R-HSA-977444 | 40 | 18 | 10285 | 3229 |
GNG3,GNAI3,KCNJ2,GABBR1,GNB1,ADCY2,GNG7,GNG10,KCNJ3,GNG5,GNG2,KCNJ10,GNG12,GNAI2,ADCY3,GNGT2,GNB3,MIR197 |
| 4.876e-02 | -3.02 | HCK (HCK proto-oncogene, Src family tyrosine kinase) | protein interactions | 3055 | 183 | 62 | 19454 | 5460 |
CASK,CRKL,FASLG,HNRNPK,KRAS,KIT,AKAP12,PRPS1,BAG2,PRPSAP1,AGR2,FGR,FCGR1A,HSPB1,CBL,PIK3R1,FCGR2A,AGK,HSP90AB1,CDK9,MDM2,LCP2,WDCP,DNM2,TSG101,PAK2,LMNA,FRS3,IRF2BPL,HEXIM1,MET,IL6ST,CNPY3,CD2AP,PIK3R2,CCR3,HSPA5,WNT2,CYB5D2,HSPA8,IVNS1ABP,EPHA2,HSP90AA1,HNRNPC,PIK3R3,CSK,MYC,CREBBP,AR,SKAP2,USP14,ACTB,YES1,TXNDC12,ELMO1,SRC,RPL22,RPL10,KRTAP3-1,PNMA1,GAB1,TRIM27 |
| 4.884e-02 | -3.02 | human chr5q22.3 | chromosome location | human chr5q22.3 | 13 | 6 | 26134 | 5823 |
TICAM2,PGGT1B,CDO1,TRIM36,FEM1C,TMED7 |
| 4.886e-02 | -3.02 | eNOS activation | REACTOME pathways | R-HSA-203615 | 12 | 7 | 10285 | 3229 |
DDAH2,CYGB,LYPLA1,CAV1,HSP90AA1,DDAH1,AKT1 |
| 4.886e-02 | -3.02 | VLDLR internalisation and degradation | REACTOME pathways | R-HSA-8866427 | 12 | 7 | 10285 | 3229 |
AP2S1,MYLIP,VLDLR,NR1H2,PCSK9,AP2A1,AP2M1 |
| 4.886e-02 | -3.02 | P2Y receptors | REACTOME pathways | R-HSA-417957 | 12 | 7 | 10285 | 3229 |
P2RY1,GPR17,P2RY11,P2RY4,P2RY12,LPAR6,P2RY10 |
| 4.886e-02 | -3.02 | Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | REACTOME pathways | R-HSA-75035 | 12 | 7 | 10285 | 3229 |
SFN,CDK1,YWHAG,YWHAH,YWHAZ,CCNB1,YWHAB |
| 4.890e-02 | -3.02 | SGCA (sarcoglycan alpha) | protein interactions | 6442 | 106 | 38 | 19454 | 5460 |
GGCX,PEX3,TMEM30A,SLC7A11,ATP1A3,DAG1,TM9SF4,ACP2,MSMO1,SLC25A17,SLC25A4,MGST3,SFXN2,STX10,SGTA,XPO5,PRSS8,DNM2,GLT8D1,LEMD3,TMEM59L,MED23,HSPA13,LGR4,SLC35E1,TMEM59,ALG11,ARFGEF1,FASTKD5,DAD1,ACVR1B,CMTM6,BSCL2,LPAR2,ITM2B,FSTL1,ATP2C1,DDR1 |
| 4.890e-02 | -3.02 | H2AB2 (H2A.B variant histone 2) | protein interactions | 474381 | 106 | 38 | 19454 | 5460 |
GLE1,H2BC11,ZNF574,MRPL51,RPL18,TRMT1L,H2AB1,PAIP2B,RPS15,ZNF592,YTHDF1,STAU1,BRIX1,SSRP1,AATF,MRPL52,RBM23,PPM1G,NLE1,RPL3,H2BC12,CCDC86,MPHOSPH10,ZCRB1,FTSJ3,RPS2,RSBN1L,RPS5,ELAVL4,RRP7A,ZSCAN25,NGDN,RPS10,RPS16,RPS3,KRR1,RPLP2,PWP2 |
| 4.890e-02 | -3.02 | PTN (pleiotrophin) | protein interactions | 5764 | 106 | 38 | 19454 | 5460 |
RBM23,EVA1A,GADD45A,SAT1,PTN,ITGAV,TOMM20,PFDN1,PSMB10,FTL,TAF1D,MSX2,COX6C,CAAP1,MAD2L1BP,SSR1,ARL15,GSTP1,SUPT7L,CRELD1,NAP1L5,APOBEC3G,FEZ1,SGTA,RPLP1,GTF2F1,PTPRZ1,MKKS,ACTB,GADD45G,BCCIP,GLYAT,CACNB4,GPRASP2,CTNNB1,CSTA,RIT1,BCL2L1 |
| 4.890e-02 | -3.02 | MELK (maternal embryonic leucine zipper kinase) | protein interactions | 9833 | 106 | 38 | 19454 | 5460 |
CAMK2G,FTL,PTGES3,SRSF12,RTKN,TESK2,FAM53C,P4HA2,PSMG4,SF3B1,PNMA2,TUBB4B,EZH2,AGAP1,PPP1R8,H1-5,CDC42,SIPA1L1,TAX1BP1,KCTD3,EIF2S1,ZNF622,CDC5L,FIBIN,EIF4E2,CD79B,CCNF,RAC2,YWHAZ,LMNB1,PSMG2,YWHAB,FAM110B,BABAM1,CUL3,MYC,YWHAG,YWHAH |
| 4.907e-02 | -3.01 | cyclin-dependent protein serine/threonine kinase activator activity | molecular function | GO:0061575 | 15 | 8 | 18094 | 5411 |
CKS2,MNAT1,CKS1B,CDK5R1,CCNB1,CCND1,CCND3,CCNY |
| 4.907e-02 | -3.01 | ubiquitin-protein transferase activator activity | molecular function | GO:0097027 | 15 | 8 | 18094 | 5411 |
CDKN1B,RBCK1,FZR1,CDC20,RING1,FBXW7,UBE2L3,UBE2N |
| 4.912e-02 | -3.01 | coreceptor activity | molecular function | GO:0015026 | 56 | 23 | 18094 | 5411 |
GPC4,NRP1,CCR5,IL2RG,CD4,NECTIN2,CXCR6,CXCR4,PTK7,RGMB,LRP6,CD80,CD28,IL6ST,CD86,LY96,ACKR3,RGMA,RAMP3,IL1RAP,ITGAV,IL2RB,GPR15 |
| 4.914e-02 | -3.01 | MID2 (midline 2) | protein interactions | 11043 | 265 | 87 | 19454 | 5460 |
CSK,TRIM32,GORASP2,GMNN,UBE2E3,ATOSB,LGALS8,ZNF177,CDKN2AIP,BAHD1,CCHCR1,MID1IP1,TUBA1B,TRIM27,RPP25L,MAGOHB,TRIM54,CCDC42,FAM161A,CPSF4,SDCBP,CARHSP1,EGFL7,UBE2K,UTP23,ZNF24,USP2,KXD1,ZNF688,UBE2N,BRMS1L,PPP1R18,JOSD1,PPP4C,TCEA2,ZNF451,EIF1AD,TFPT,FASTKD5,STX11,CUL3,ZNF250,TTC23,PRPF31,THAP7,BRCA1,GCC1,FAM107A,SCNM1,HAPLN2,ETNK2,TRIM29,TUBB,UBTD1,RORB,LMO3,LMO4,ISCU,ZBTB42,MFAP1,FAM50B,STAU1,DGCR6L,UBE2D3,UNC45A,UBE2E2,PSMD3,GAS8,UBE2D1,PSMB5,CEP57L1,IGBP1,HNRNPL,TOP3B,SPG21,ASPM,TUBB4B,TMEM14B,PICK1,ZBTB16,PSMA1,GSTT1,ENKD1,UTP25,POLDIP3,GOLGA7,AP1M1 |
| 4.918e-02 | -3.01 | TRIM54 (tripartite motif containing 54) | protein interactions | 57159 | 318 | 103 | 19454 | 5460 |
GIMAP2,KPNA2,TRIM63,SOX14,TCEA2,RBM41,BSCL2,JOSD1,UBL4A,MGARP,PPP1R18,DCUN1D1,THOC1,TNR,EXTL2,UBE2N,EIF4E2,SSX2IP,USP15,USP2,XAF1,CRADD,GTF2I,KDM1A,USP8,MBD3,VPS28,ARHGEF6,MNS1,TNFAIP1,SDCBP,LSM2,ZNF267,FAM161A,HYAL2,PYGM,ELMO1,TRIM54,DNASE1L1,CSNK2B,UBE2I,UBE2E3,PAIP2,CCHCR1,PPIG,AAMDC,NTAQ1,CHCHD2,ZBTB16,PSMA1,SEMA4C,PIWIL1,ENKD1,PICK1,HGS,GNG13,SPG21,MEAF6,TTC9C,CYTH4,PRPF18,G2E3,RAB35,CEP57L1,TSG101,KRT8,UBE2D1,AK2,DRG2,TLR10,TMEM30A,PDZK1IP1,HSPB1,SHC3,GAS8,UCHL3,UBE2D3,FAM50B,DNAL4,MFAP1,EHHADH,LMO4,LMO3,CDKN1A,TCAP,CAVIN2,RIMS3,DYNLL1,UBE2V2,USP5,MAD2L2,SCNM1,PRMT5,EXOC8,ARMC7,SYCE3,LMO2,ZNF250,PIK3R3,AK3,SMARCE1,TTC23,RBM15B |
| 4.919e-02 | -3.01 | positive regulation of cell cycle | biological process | GO:0045787 | 335 | 113 | 18204 | 5365 |
PRKCA,MIR214,FEN1,MIR222,ARF6,CCND1,BECN1,AIF1,MIR221,CYP1A1,PLSCR1,CDK4,PSMD10,MAD2L1,NUP62,MACROH2A1,LRP6,ANAPC11,DYNLT3,PAGR1,TERT,PRKCE,UBXN2B,RB1,RANBP1,MIR495,CDC7,AKT1,PKP4,IL1B,NSFL1C,VPS4B,NKX3-1,POLDIP2,PIWIL2,PROX1,DRD3,DDRGK1,SRPK2,IGF1,TTL,TNF,SMC4,IL1A,DUSP3,TGFB2,ROCK2,IL10,CALR,OVOL1,FGF10,TRIM32,TMOD3,MRGPRX2,NPR2,MSX1,MAGEA4,ADAMTS1,RAB11A,CCND3,SMARCD3,NR2E1,MIR208A,PLCB1,CUL3,UBE2B,RGCC,RACGAP1,LSM10,MSX2,CCNB1,CDC73,PPP1R10,MIR519D,MEPCE,RAD21,SIN3A,SLC6A4,NUDT16,NDC80,RRM1,WNT10B,MAD2L1BP,CD28,MIR29A,EZH2,NCAPG2,FGFR1,MIR26B,PSRC1,TAS2R13,TAS1R2,CDK1,PHB2,MTA3,MIR590,PTPN11,TRIM21,CCNY,BIRC5,PAFAH1B1,DTL,MDM2,UBE2E2,CDC16,CDC23,EIF4E,KIF3B,USP2,IGF1R,CDC20,CDC42,NUPR1 |
| 4.921e-02 | -3.01 | Nucleotide sugar biosynthesis, eukaryotes | KEGG pathways | M00361 | 9 | 6 | 7161 | 2463 |
GMPPA,UGP2,GALE,UAP1,UGDH,GMPPB |
| 4.921e-02 | -3.01 | Nucleotide sugar biosynthesis, eukaryotes | KEGG pathways | hsa_M00361 | 9 | 6 | 7161 | 2463 |
UAP1,GALE,UGP2,GMPPA,GMPPB,UGDH |
| 4.923e-02 | -3.01 | system development | biological process | GO:0048731 | 3533 | 1082 | 18204 | 5365 |
SDCBP,BRINP1,ACTL6B,MDM2,SDC4,TNFSF10,STK4,HTR5A,TP53,MAP1S,NRGN,TNFAIP6,HPCA,EPOP,NDUFV2,MAP3K3,MIR1-1,LEPR,SOD2,CSGALNACT1,GABRA1,CNP,FTSJ1,EHD1,ITGAV,ACKR3,MGP,MARVELD1,UGT1A1,TMEM38B,PCGF2,RAD1,LAMB2,LARGE1,BRINP2,GHR,PPIB,HSPA8,KLF4,ARF4,APLNR,TLR4,RPS15,DLG4,CER1,S100B,GABRA2,HMCES,GPM6A,ZBTB14,SIAH1,MIR195,ATAT1,EIF2B2,LHX2,SLC22A6,HEXB,CCDC134,S100A6,HELLS,BPNT2,CDKN1B,IMPACT,NREP,SUFU,TNNI1,PAPSS2,EPCAM,TWSG1,ACTB,TNF,GALC,CX3CL1,NGRN,PPT1,NAB2,RBPJ,ORMDL3,TOP2B,FGF7,CXCL12,BCL6,PFDN5,PHACTR1,CDK5,EPHB6,EMILIN1,TBC1D24,ITGB8,MOBP,PITPNA,GPR15,PLG,DUSP10,CHRDL1,FOLR1,MPST,NDN,DRGX,CDKN1A,MDFI,ILK,TMEM107,TAFAZZIN,NAB1,ZNF365,TYMS,CITED1,RB1,NPY5R,SEC61A1,GJA1,CXCR3,MIR17,MYEF2,CNTN1,CEBPG,ALDH1A3,ARF6,CLDN3,NHEJ1,FOXC2,NEUROG2,TENM3,RORB,KCNC1,EFNA3,ADD2,KCNB1,NELL2,TLR3,EPHA4,SAT1,IFT172,IGF1R,FLCN,SFRP1,FZR1,PPIA,CDC42,NUPR1,CRYAB,FRZB,YWHAH,ID1,RAB18,HNF1B,CCL3,BCL10,REN,SCG2,PCSK2,CNTFR,RFX4,IL6ST,UNC119B,HEY2,BARX2,CDNF,MAB21L1,C1QL2,STK3,DOK4,TYROBP,SHC3,WDR37,SWAP70,CMA1,ING2,EFNA5,DKK3,BEND6,KLHL3,OPHN1,HTRA2,HSPA5,MYD88,NPTN,CBLN2,CRYBB2,TULP3,NUDT1,MAP2K3,GRXCR1,PCDHB1,LTB,GABRG2,RERE,GJB1,RAB29,LIAS,HYCC1,EIF2B3,GAS8,SPINT2,COL3A1,HSD11B1,DKK1,SPOCK1,RFLNA,FEM1B,HOXB1,FAM20C,SEMA5A,CCR6,RNF8,STAT6,HAND2,MBD3,CXCL1,SLC31A1,C9orf72,FKBP1A,KDM1A,HDAC5,MAP2K1,PPP1CC,CRYBB3,KCNIP2,ACTL9,WDR11,HOXC4,GHRL,RGN,PROK1,RHEB,ABITRAM,SOX9,CBL,BECN1,SNAI2,DICER1,LTBR,EFNB1,CBLN1,NAPA,RAB13,CYP1A1,BRINP3,CHST11,RAB3A,DLG1,PAFAH1B1,IFT52,NLE1,TCAP,TAF10,ATP5PB,IL17F,PIK3CA,CD47,TIAM1,BMERB1,ZC4H2,NPY2R,NDUFS2,NLGN1,TNNT2,NUP107,NTF4,FIG4,ROCK1,PDCD4,P2RY12,NEO1,LYPLA2,TMEM59L,ETV6,MIR143,MPZ,GNPAT,NEGR1,PRDX1,SERPINI1,IL18,RB1CC1,NDE1,ELK3,GNB4,MACO1,HIKESHI,ACO2,CRYGA,PIK3CG,THY1,INSIG2,CD40LG,PMP22,FASLG,IL15,MTPN,RRM1,LLPH,ALPL,SLC38A2,CD248,VEGFA,SAMHD1,TIMP1,NF2,WDR19,NR2E1,RAN,NR0B1,CUL3,RAPGEF5,CTNNBL1,PRKACB,AMIGO1,FOXP2,YWHAZ,CRYBA4,SOX14,HS2ST1,STMN2,NIBAN2,FZD4,CAMK1,PCDHB13,RXFP2,NIF3L1,LGALS8,SPTBN1,LHB,SLC2A1,RS1,SCN3B,SCYL2,TRIM32,CYB5D2,GLUL,ASB1,EGFL7,RAB33B,FA2H,SYK,NPY1R,OMG,PROM1,CCR4,SAV1,ACVR1B,PCYT1B,FBXW7,EAF2,NOG,S100A8,ZDHHC17,HDAC6,STK11,MAP2K6,NPPC,IGF2BP1,JRKL,NHERF1,CCL2,SYNGR3,POU1F1,PDE2A,CBLN4,RDH10,CACNB4,MIR16-1,CHRM3,DRD1,TMEM231,HSD17B3,CLRN2,MEA1,G6PD,RARRES2,TLR2,MYLIP,GLRB,CYP1B1,FKBP4,NTN4,PTHLH,PICK1,VPS54,BPGM,XRCC5,FEZ1,NPTX1,IMMP2L,CRYGB,RAB23,ZNF513,THOC6,NKX3-2,GPM6B,TMEM100,BBS5,ACVR1C,ACSL4,MMP14,POPDC2,SDC2,TRAF3IP2,EIF4E,BAX,HEXA,HAPLN2,IL6,NDST1,ID4,MMP9,ASPM,SOX21,PADI2,ADIPOR2,DEGS1,AKT2,ACTL6A,SCLT1,COPS2,ATXN10,PDLIM4,UHMK1,MPV17,AKT3,FOXP3,MATR3,ERRFI1,FUT1,SPRY1,BVES,IQSEC1,EMC10,SMARCE1,SMN1,MAD2L2,SSBP3,PAX6,WNT10B,EDNRA,FOXS1,GUCD1,UCN,DRP2,NUS1,POPDC3,HHIP,TLR9,PLCB1,ORMDL1,TNFRSF1B,SMARCD3,ADM2,ZNF24,ZBTB16,LECT2,FHOD3,SEMA4C,AQP11,SELENON,TMEM204,TNIK,MEF2B,IGF1,APH1A,HMX2,DIO3,UCP2,SPRED1,CALR,ASPA,TNFAIP3,GH1,RBBP4,BAK1,PCDH9,VDR,MAP1B,GSTP1,PRPS1,B4GAT1,NEUROD6,OXTR,TOX,ELAVL4,CLP1,WNT7A,PPP3CA,NPY,AKT1,BMP1,CA10,IL1B,TGFB3,NYAP2,AGR2,B9D1,GPC1,ADAM21,ITGA2,FKRP,CKB,B4GALT1,FGF1,MIR125A,ACP5,NRP1,PCSK9,MATCAP1,RPGRIP1L,CDK5RAP3,CPLX2,ACER3,RGMA,ROGDI,RPL13A,XBP1,CPE,MET,KIT,FLRT3,ANP32B,CCND1,PAK2,CYTL1,MSH6,TGFBR2,SOD1,RND2,AR,CNR1,KIF2A,NRSN1,CXCL8,LPAR1,DIPK2A,BLOC1S2,CLIC4,SVBP,ERCC3,RRAS2,FKBP8,MITF,SCN1B,EPYC,UBP1,TMEM14B,CFAP418,ATXN1L,SRSF1,P2RY1,FGFR1,VASH1,PRDX2,TBCE,HELT,COMT,NKIRAS1,SIX5,ADORA1,ENC1,SELENOP,SMG9,C1QL1,DCLRE1C,HDAC11,PTPN11,CCL8,CDK6,TFPT,UGDH,FOXI3,ASTN1,DHRS3,SLC4A10,FKBP10,DDIT3,CLN8,TRAK2,NR4A2,MNAT1,CNTN2,SLC6A4,TPBG,SRP54,CRYBA2,EGR1,PLPPR1,IL34,MYRF,MKKS,FANCG,FZD6,NCSTN,CAPG,EZH1,CHRNA7,EZH2,IER2,CHRNB2,UPF3B,IL3,TMOD1,GAB1,HECTD1,BTG2,UFD1,TSPO,PRKCQ,RHOJ,PGR,AAMP,NSDHL,ST8SIA4,LIPA,RACGAP1,CLSTN3,EMX1,ARCN1,PTGER4,SFRP4,B4GALT6,DDRGK1,PLAAT3,MMP21,FGF17,NAA15,RBBP7,RAF1,IL10,ROCK2,FERD3L,TAGLN3,NKX6-2,CDKN2C,MSX1,MIR145,CCM2,CX3CR1,CNTNAP1,ATL1,PRKX,RAB6B,TMEM106B,THBS3,RAB11A,CORO1C,HMGB1,GABRB3,MME,EPHA2,KLK6,RAB6A,PTK7,NTNG2,LBX1,BCCIP,CXCR4,MAMDC2,TRIM46,AGER,ZNF304,HRAS,MIR23A,RHOB,BATF,TAPT1,ICOS,INPPL1,KCNA3,SPHK2,BORCS8,ASIC2,NKIRAS2,ZBTB45,H2AX,FBXW11,RAG1,TRA2B,LGI1,ANKH,ADNP,CTTN,PRKCA,NEFL,TFDP2,SCN2B,DDR1,CRELD1,ACVR1,LDB1,POMT2,CACYBP,INA,GAS2,UFM1,HSD17B1,TMEM126A,CDH11,COX7B,DNAJC19,GSTM3,DNAJC30,THOC2,DLX1,LY6H,MYC,CREB1,GPR17,SEMA6C,CDC20,TDRD7,CYP26A1,APLN,ATP6AP2,CDK1,LNX2,OSR2,SMAD5,EIF2S2,EED,HSP90AA1,TGIF2,CDK5R1,FGF12,SNAP25,KDM4B,ACHE,ADGRL3,COQ8B,PRDX4,SOCS3,CAV1,RBFOX2,TAB1,RC3H2,ODC1,BLOC1S3,PTPRZ1,MEF2C,CAV3,OR10A4,GABRB2,ZMPSTE24,RUNX1,NRSN2,WWP1,IFT57,SMAD2,CLDN1,PTN,EGR2,PSEN1,LILRB4,GJC1,ATG9A,KRAS,NOTCH2,MBD5,SRPK2,CRIP1,ACTA2,SLC6A3,POLB,TGFB2,IL1A,CRYBA1,PAK6,FGF10,ATP5F1B,PCNA,RING1,ADAMTS1,PCDHB8,SOX2,GAL3ST1,WASL,FABP7,PEX13,DYRK1A,VPS4B,DDIT4,TPPP,CDH13,ADTRP,PROX1,GREM1,WASF3,ATP2B4,SMAD1,TTC8,NCKAP1,CHRM1,DPPA2,CRYGD,KLHL1,PLS3,TMOD2,FOSL2,LTA,LRP12,SHC1,TMX2,CLRN1,CRHR1,IDH1,MIR20A,PRCP,FZD3,CTNNA1,MTF1,TNR,OGN,CTNNA2,ATP5PF,ATP1A2,PICALM,SLC39A3,CAMSAP2,GPR37,DYNLL1,DOK5,TAB2,IFNG,SNX10,HOXB8,TRIM45,PRKRA,MEF2A,MIR135B,LGR4,EXT1,PTGES3,MGARP,TNFSF12,KCNJ11,PDSS2,NME1,MTMR2,DAG1,IGSF21,CDK20,SLC25A46,SRC,ADRA1A,C1QL3,SERPINH1,ANGPT1,HEXIM1,TCOF1,NOVA1,KRIT1,FAM151B,ATF4,WIF1,LEP,NCDN,PTS,GCNT3,SOX3,SNX17,BMPR1A,SIGMAR1,SLITRK1,MECP2,SMARCB1,EFHC1,BMPR2,TRAPPC4,ADGRG1,SEMA7A,TAL2,EXOSC3,MOG,PQBP1,TRIM3,ITM2B,MAN1A2,INSM2,NTRK3,FLRT2,MYT1L,NTRK2,CTNNBIP1,HS3ST3A1,TRNP1,BLOC1S5,NBN,EIF2B5,METTL14,STC1,NR2F6,SARM1,SLC7A11,ATG16L1,MIR24-1,SMAD3,KCNJ10,CSRNP1,HNRNPD,WNT2,CCN3,RHBDD3,COL1A2,TMEM108,TEX19,SLITRK2,EIF4A3,RAP1A,SEC63,GIT2,CLU,GNB1,TMIGD1,MACROH2A2,OTULIN,MINAR1,NKX3-1,AKR1B1,PKNOX1,FCGR2B,RPS7,ELP3,BMPR1B,IRF2BPL,TAFA1,FOS,SLC11A2,CHI3L1,DISC1,UGP2,SYBU,RPL24,ARG2,FUT9,B3GNT2,SSNA1,SPATA2,KCNJ8,PLP1,EFHD1,P3H1,FGF13,SRI,GNA11,CD2AP,ZDHHC16,PLN,AGGF1,POU3F4,FXR2,TRAF6,NLGN2,MARCKSL1,NDP,FKTN,LRTM2,RAB35,SFTPD,HOXD12,ACAT1,NRN1,NINJ1,MYO6,FOXP1,ALCAM,PDE6A,LDB2,FGR,LRRC4,UBE3A,SLITRK5,CSK,PCDHA5,PCDH17,BGLAP,CRMP1,UBB,COX6B1,JUNB,OTX2,KCNA2,PPP1R17,LDLR,HSPD1,GRIK1,PRELP,NEUROD2,PPARA,FLOT1,IFNGR1,EMX2,VEGFC,MAP4,SLC1A3,GPR37L1,ELK1,SIN3A,CLDN11,TRAPPC6B,AQP2,VSTM4,CFC1,VAV2,SLC32A1,SNAPIN,RBBP9,LIG3,GJA10,NDUFS3,TCF21,PCK2,ESS2,DNM2,EMP2,RTN4,OLFM3,LST1,RHOBTB3,ENPEP,UQCRQ,CPNE1,MSX2,ANAPC2,PAFAH1B3,CD9,MIR21,ECRG4,INHA,PSKH1,RBFOX3,RNF103,EP300,CERS6,PDCD10,PIK3R3,WDR77,OVOL1,BOK,CAMK2G,CTNNB1,SLC1A1,NPR2,SLC1A2,HYAL2,SHLD1,IFT25,CYFIP2,GPX1,RALA,LMNA,MINAR2,MIOS,NDNF,PRMT5,SEMA3C,AMELX,SMAD4,CEND1,PDLIM3,BCL2L1,STXBP1,JAK2,PTEN,MCPH1,STAT1,VLDLR,LRP6,VXN,DVL2,L1CAM,TMEM215,GSK3A,UGCG,SMCHD1,CD34,TUBA1A,GRIA1,LMO4,POLL,TIMM8A,ATP5IF1,PLAA,SLC8A1,CRKL,GYS1 |
| 4.924e-02 | -3.01 | placenta development | biological process | GO:0001890 | 150 | 54 | 18204 | 5365 |
SOD1,PTN,ETNK2,PPARG,DNAJB6,NSDHL,TPPP3,NDP,CCNF,GHRL,CDKN1B,HTRA1,CCDC134,LDOC1,DEDD,CITED1,KRT8,HSP90AB1,MAP2K1,BMPR2,MDFI,CTSB,CYP27B1,SOCS3,STK3,LEP,TFEB,PLG,HEY2,ITGB8,STOX2,CSF2,RTCB,SPP1,AKT1,MME,JUNB,VASH1,SPINT2,BIRC2,PRDX3,VDR,TEX19,WNT2,GJB2,IL10,RBPJ,PARP2,STK4,PLAC1,TCF23,TAF10,STC1,NOTCH2 |
| 4.927e-02 | -3.01 | response to dopamine | biological process | GO:1903350 | 51 | 21 | 18204 | 5365 |
GNAI3,HTR1A,CALY,HTR2A,GNG2,NSG1,NHERF1,COMT,SIN3A,GNB1,SULT1A3,GNAQ,GNA11,GNAO1,DRD3,SLC1A1,PTGER1,GNA14,DRD1,GSK3A,NCSTN |
| 4.932e-02 | -3.01 | SMN-Sm protein complex | cellular component | GO:0034719 | 18 | 9 | 19108 | 5553 |
SNRPD2,SMN1,SNRPG,SNRPE,GEMIN7,GEMIN8,SNRPD1,SNRPD3,SNRPB |
| 4.932e-02 | -3.01 | COPI-coated vesicle membrane | cellular component | GO:0030663 | 18 | 9 | 19108 | 5553 |
KDELR2,KDELR1,DIPK2A,ARCN1,TMED7,TMEM199,COPE,TMED3,COPZ2 |
| 4.932e-02 | -3.01 | CYT_DCMP_DEAMINASES_2 | prosite domains | PS51747 | 16 | 8 | 12186 | 3388 |
APOBEC3G,DCTD,APOBEC3B,APOBEC3A,APOBEC3C,APOBEC3H,APOBEC3F,APOBEC3D |
| 4.935e-02 | -3.01 | CCR1 (C-C motif chemokine receptor 1) | protein interactions | 1230 | 348 | 112 | 19454 | 5460 |
S100A11,CBR3,SETD7,CYP4F22,DHRS1,F2,PYCARD,SFN,NIBAN2,HMGCS1,CCL23,TRIM29,DYNLL1,STAT1,AKR1C2,ATP5F1B,PI3,SIGMAR1,CRYAB,RDH12,UBL3,DUSP14,H1-5,CD59,EHD1,RER1,GDPD3,UFL1,LYPLA2,AZGP1,NT5C3A,CDSN,GNA14,RAB5A,RHOG,CSTA,RAB3D,GSTM3,HSPB8,CHI3L1,DNM2,FABP5,CYB5A,S100A8,PLS3,SDR16C5,GNAQ,CCR1,STX12,LYPLA1,CYB5R1,SERPINA3,IMPA2,RAB18,SAR1B,SEC11A,JAK1,STK24,NAPA,EPHA2,GSTK1,GJB2,CREB3,HMOX2,YES1,CD47,RAB14,KLK9,ACOX1,MACROH2A1,ALB,GLTP,CALML5,KLK6,PICALM,IDH2,JUP,GPX3,OXSR1,ARHGAP1,CCL3,ABHD5,PLP2,TPST1,TTR,CCL8,UGP2,LCP1,POR,DHRS7,NFKB1,CCL5,HP,PRNP,PLG,LY6G6C,HRAS,CDCA3,SERPINA1,JCHAIN,C1QC,TCAF2,FNTB,SPRR1B,GNG10,MAP2K3,EEF1A1,TF,CCL2,CTSC,GLUL,NSDHL |
| 4.936e-02 | -3.01 | regulation of neuron projection regeneration | biological process | GO:0070570 | 34 | 15 | 18204 | 5365 |
STK24,EPHA4,TNR,CERS2,MIR222,SPP1,KLF4,FKBP1B,MIR221,NEO1,MAP2K1,IGF1R,RGMA,PTN,THY1 |
| 4.936e-02 | -3.01 | regulation of mitophagy | biological process | GO:1901524 | 34 | 15 | 18204 | 5365 |
STUB1,FBXO7,TSPO,TP53,VDAC1,FKBP8,GSK3A,FBXW7,SLC25A4,RNF41,USP30,CTTN,PARL,SLC25A5,BNIP3L |
| 4.936e-02 | -3.01 | virion assembly | biological process | GO:0019068 | 34 | 15 | 18204 | 5365 |
TSG101,PC,CHMP2A,CHMP5,USP6NL,VPS28,CHMP1B,RAB1B,RAB1A,SPCS1,CHMP2B,CHMP4C,VPS4B,CHMP1A,VPS4A |
| 4.936e-02 | -3.01 | retrotransposon silencing | biological process | GO:0010526 | 34 | 15 | 18204 | 5365 |
MOV10,SIRT7,APOBEC3B,MAEL,PIWIL4,ASZ1,APOBEC3A,DDX4,APOBEC3H,APOBEC3G,APOBEC3C,PIWIL2,TEX19,APOBEC3F,PIWIL1 |
| 4.936e-02 | -3.01 | regulation of transcription regulatory region DNA binding | biological process | GO:2000677 | 34 | 15 | 18204 | 5365 |
IFNG,GTF2B,ZC4H2,TRAF6,ZNF593,PAX6,IGF1,MAD2L2,DDRGK1,RB1,PSEN1,TRIM6,HAND2,NIBAN2,HEY2 |
| 4.946e-02 | -3.01 | blood circulation | biological process | GO:0008015 | 418 | 139 | 18204 | 5365 |
ACTA2,ADIPOQ,TNF,SNX5,CYB5R3,CYP11B2,HRH2,ROCK2,SCN3B,SMAD3,MAP2K3,DBH,ATP1A1,AGTRAP,NPR2,AVPR1B,COL1A2,SLC1A1,GPX1,OXTR,YES1,SLC23A2,KCNMB1,NPY,RANGRF,BRS3,DDAH1,CYP4F12,NPY1R,GCLC,RGS2,KCNMA1,CXCL12,CXCR4,EMILIN1,DRD3,ADRB2,MIR23A,CXCL10,OR51E2,MAP2K6,NPPC,GNB3,PDE2A,STAT1,NCALD,GSK3A,KCNJ8,GUCY1B1,SCPEP1,DRD1,CHGA,TAFAZZIN,ASIC2,GNA11,OPRL1,CYP11B1,MIR17,PLN,SCN2B,PRCP,UTS2,GJA1,ADRB3,CD38,OLR1,KCNJ3,FOXC2,ATP1B1,HBB,CNR1,AR,SLC8A1,SOD1,CARTPT,ATP1A2,PIK3CA,IMMP2L,CACNB2,TCAP,TNNT2,AKAP12,IER3,FERMT2,SCN1B,ROCK1,TACR3,PTP4A3,CDC42,SOD2,COMT,RASL10B,EXT1,P2RY1,KCNJ2,ANGPT1,ATP6AP2,APLN,SOD3,ADRA1A,ADORA1,SRC,HTR2A,REN,E2F4,ADRB1,SNTA1,SMAD5,LEP,GPR37L1,FGF12,VEGFC,PPARA,CAV1,SLC6A4,EPO,MECP2,EDNRA,VSTM4,MKKS,HTR1A,VEGFA,CMA1,UCN,BMPR2,CAV3,UTS2R,EMP2,ADM2,KCND3,TACR1,KCNMB2,TNNI1,PPARG,ENPEP,GJC1,MIR153-1,CTNNBIP1,MIR21 |
| 4.950e-02 | -3.01 | MPPE1 (metallophosphoesterase 1) | protein interactions | 65258 | 81 | 30 | 19454 | 5460 |
TMBIM6,CSGALNACT2,LRFN3,EDEM1,BTN2A2,BPNT2,CGRRF1,AMIGO1,EXT1,LRP12,APEX1,SPPL3,GALNT4,HYAL2,DIPK1A,GPC4,FUT8,GINM1,TMEM39A,CHPF2,POMT2,TMEM59L,NXPE3,LRRC3,GALNT12,HSPA5,GALNT2,FKRP,B4GALT7,USP30 |
| 4.950e-02 | -3.01 | DEPTOR (DEP domain containing MTOR interacting protein) | protein interactions | 64798 | 81 | 30 | 19454 | 5460 |
MAGED2,EIF3K,NDUFB4,PPP2CB,TRAF1,HNRNPL,XPO1,CSK,TNFAIP3,PIM2,FBXW11,LSM6,UBE3A,SQSTM1,PSME1,FBXO25,ARF4,FBXW7,DDX39A,UQCRC1,KIF2A,CNP,SYNRG,UBL4A,MAPKAPK5,PSMB3,SMARCB1,RNF126,TFRC,EIF2B3 |
| 4.950e-02 | -3.01 | C11orf58 (chromosome 11 open reading frame 58) | protein interactions | 10944 | 81 | 30 | 19454 | 5460 |
RPLP1,EGLN3,LDHA,CAVIN2,HYPK,NONO,TRA2A,PSMB2,CHORDC1,SHC1,SF3B1,EWSR1,PRDX6,HADHA,HSPD1,RPA3,BAP1,MAP1B,AHCYL1,PTN,STAU1,EEF1G,OXCT1,THRAP3,POLR2C,RPLP0,RPA2,PSMB7,CBX3,BZW2 |
| 4.950e-02 | -3.01 | FAM83D (family with sequence similarity 83 member D) | protein interactions | 81610 | 81 | 30 | 19454 | 5460 |
CRYAB,CSNK1A1L,TUBB4B,PSMC3,CSNK1A1,TP53,CSNK1E,RFXANK,FBXW7,STAU1,BACH1,DYNC1I1,KRAS,FTL,GADD45A,RPA3,MAP4,SLX1A,CUL3,CDC16,GMNN,SUV39H1,AR,HDAC6,ATG7,TUBB,DYNLL1,EGLN3,TRAK2,NRSN1 |
| 4.950e-02 | -3.01 | H2BC17 (H2B clustered histone 17) | protein interactions | 8348 | 81 | 30 | 19454 | 5460 |
ICAM1,UBE2H,H2AC4,PSMD14,CD81,BTF3,USP14,AKT1,MOV10,RPL7A,APEX1,ESR2,VIRMA,MEAF6,ARL6IP5,FGFBP1,PRKRA,H2AZ1,ZNF330,HEXIM1,H2AX,H2AJ,KBTBD4,HEXA,PIAS1,MEPCE,CACUL1,JADE1,AKT2,MAP1B |
| 4.952e-02 | -3.01 | primary active transmembrane transporter activity | molecular function | GO:0015399 | 151 | 55 | 18094 | 5411 |
COX4I1,NDUFB8,ABCB1,ABCB9,NDUFS6,ATP6V1C1,ATP6V0B,NDUFS3,ATP6V1G2,ABCG2,KCNJ11,UQCRC1,ATP6V1G1,UQCRH,NDUFB7,ATP8A1,ATP2C1,CYB561D2,NDUFA4,NDUFS2,NDUFC2,ATP1B1,COX7B,ATP1A2,ATP1A3,COX4I2,ATP6V1D,NDUFA2,NDUFB10,TOMM20,ABCC2,NDUFA1,NDUFV2,NDUFB6,NDUFA12,COX5A,COX8A,COX6B1,COX7A1,CYBRD1,CYC1,ATP6V1E2,NDUFB5,ATP2B4,CFTR,NDUFA5,ATP6V1A,ABCC5,ATP1A1,NDUFB4,CYB5A,ATP6V0E1,NDUFS8,KCNJ8,ATP5F1B |
| 4.953e-02 | -3.01 | protein complex oligomerization | biological process | GO:0051259 | 256 | 88 | 18204 | 5365 |
TP53,STK4,KCTD12,KCNB1,G3BP2,PEG10,STOML2,KCNC1,KCNF1,EHD1,SOD2,SSBP1,BCL10,MIF,KCNJ2,KCNA2,STK3,LRRC8A,HSD17B8,UGDH,GNMT,PRNP,HOMER1,RRM1,SIGMAR1,CRYZ,AQP2,MCOLN1,CHMP2A,THG1L,SAMHD1,KCTD17,TMEM70,B2M,CALHM3,KCND3,IFIH1,CD247,AQP11,EHD4,CLDN1,AQP4,NACC2,HSD17B10,BOK,CRTC2,KCTD10,SHMT1,RS1,ATL1,SLC1A2,ASIC1,TWNK,COL1A2,KCND2,KCTD11,NLRP1,KCNG3,ZNHIT6,KCTD15,FKRP,SLC31A1,WDCP,PYCARD,PRND,HSCB,MAT2A,FARSA,KCTD3,USP16,CBR4,EHD3,NLRP6,KCNS1,KCNA3,LRRC8D,ALOX5AP,ACACA,TNFAIP1,KCTD16,KCTD9,NLRP3,CD2AP,NINJ1,ACOT13,LRRC8C,TIFA,ALDH1A3 |
| 4.968e-02 | -3.00 | organic hydroxy compound metabolic process | biological process | GO:1901615 | 479 | 158 | 18204 | 5365 |
AKR1B1,HSD17B6,MPDU1,DPM2,SULT1A3,HAND2,PFKFB2,DPAGT1,FKRP,LBR,DRD3,LDHA,CH25H,GK2,GDPD3,CYP3A5,CYP4F12,MSMO1,RDH11,AMACR,SLC1A1,DIO1,CYP2R1,CTSK,DBH,RDH12,NPC2,STAR,CYP11B2,PCBD1,IGF1,CYB5R3,DIO3,SLC6A3,DHRS7,TGFB2,OSBP,GK5,NPC1L1,HSD17B10,ALDH1A3,CYP1A1,CYP21A2,CYP2C8,ACOT8,MVD,HSD17B1,PNPO,CFTR,DOLK,G6PD,CYP1B1,NFE2L1,AKR1A1,SPTSSA,DRD1,THTPA,ACER3,SLC16A10,RDH10,HSD17B3,CYP11B1,NUDT3,IDH1,FDFT1,DIO2,CITED1,ERG28,VLDLR,CYP2C9,LDHAL6B,CBR4,SPHK2,LRAT,SDR16C5,CTSB,PCSK9,SPTSSB,RETSAT,ADH1B,SULT1B1,IP6K1,IMPA2,PIP4P1,INPP4A,ACO2,SORD,GPD2,GDE1,LEP,IDH2,DHRS3,INSIG2,CYP26A1,FGFR1,COMT,ISYNA1,LDLR,DDT,ERRFI1,TRPC1,SNCB,ACAA2,LEPR,CYP39A1,TPH2,GPR37,SPR,NUDT4,CYP27A1,IDH3A,ERLIN2,TP53,DHRS4,LIPA,NSDHL,CYP7A1,OCRL,SRD5A3,CRYM,PLPP6,SC5D,ALG2,PCK2,PLCB1,NQO1,CYP2D6,ADH1A,TKTL1,IL4,FAH,FAXDC2,CYB5R1,ERLIN1,LDHB,HMGCS1,CYP2C18,NUS1,IDH3B,RTL4,MOXD1,PDE1B,PTS,AKR1C2,CLN8,NR4A2,AKR1C1,SNX17,HTR1A,CYP4V2,FGF23,MTPN,PNPLA4,CYP27B1,MECP2,EDNRA,ALPL,AKR7A2 |
| 4.977e-02 | -3.00 | WRAP73 (WD repeat containing, antisense to TP73) | protein interactions | 49856 | 122 | 43 | 19454 | 5460 |
ARMC6,SPEF1,PFDN6,HERC4,PFDN2,RC3H2,BICD2,CCT2,MCM3,HNRNPC,CUL3,CDSN,SQSTM1,LCA5,SDCBP,EBLN2,ZC3H14,SURF6,LRRC61,PHYH,CCAR2,COPS2,S100A8,PRCC,MED4,SSX2IP,HAX1,ACTL6B,XPO1,HDAC6,DNAJB2,NDC80,PSMD3,CNOT2,UBXN6,COPS4,CCAR1,PFDN1,KLHL15,DNAJB4,RNF126,GGCT,RBM12 |
| 4.977e-02 | -3.00 | IGFBP5 (insulin like growth factor binding protein 5) | protein interactions | 3488 | 122 | 43 | 19454 | 5460 |
PDZK1IP1,SLC38A1,CXCR1,AQP2,TMEM179B,SPP1,TMEM106C,RHCG,SLC41A3,CREB3,CUL3,EPS8,F2,TSPO2,TLCD4,TMEM237,LHFPL1,GPX1,SYNE4,FNDC9,CLDN9,MFSD5,AMIGO1,HRAS,EIF1AX,MS4A7,ABHD4,LMNA,PPP2R1A,TMEM106A,TMEM45A,TIMMDC1,RPP14,KRAS,CLDN6,TF,APH1A,GPR37L1,IGF1,MRPS18B,PDIA6,TMX2,PNO1 |
| 4.977e-02 | -3.00 | SCAF11 (SR-related CTD associated factor 11) | protein interactions | 9169 | 122 | 43 | 19454 | 5460 |
ANAPC15,SNRPB,MYC,YWHAZ,ATXN1L,EZH1,APEX1,TNPO3,ESR2,SRPK2,VIRMA,RNASEH1,SNRNP40,IFI6,SNRPA,SIRT7,PSENEN,SRSF2,FBXW7,HNRNPA1,YWHAG,HMGA1,POU5F1,UQCR11,DDX23,TUBG1,EID1,H2AC4,SNRNP70,WDCP,SRSF1,PTP4A3,HNRNPL,TOP1,SUMO2,LGR4,RAF1,SUPT5H,POLR2C,CHMP4C,PSEN1,SRSF4,SSRP1 |
| 4.977e-02 | -3.00 | IL16 (interleukin 16) | protein interactions | 3603 | 122 | 43 | 19454 | 5460 |
RNF144B,PRNP,SPPL3,KCTD9,VIRMA,KRTAP3-1,KCND2,CD4,TRIM27,TRIM23,PPP1R16A,KCNJ10,KCNJ2,SERTAD3,KCNA3,PFDN5,SPRED1,SUV39H1,CSNK2A1,NTAQ1,RBCK1,BOLA2B,OIP5,KDM1A,HDAC3,ZBTB39,JAKMIP1,PPP1R12A,NPB,EWSR1,CCDC184,HSPA8,PICK1,GABPB1,ZNF526,CAMK1,CDK1,TFIP11,SMARCB1,PRR13,LNX2,LMO3,ZNF581 |
| 4.977e-02 | -3.00 | ELK1 (ETS transcription factor ELK1) | protein interactions | 2002 | 122 | 43 | 19454 | 5460 |
TUBB,CDK9,ELK1,SH3BGRL,MAD2L2,DOK4,TUBA1B,MOB4,CDK6,STARD3NL,UBE2I,BRCA1,ID1,PPP3CA,HSPB1,CREBBP,SLC25A1,GRB10,HM13,CTNNB1,EMX1,TMEM33,GRPEL1,FBXO25,HSPA5,SLC25A5,SLC25A10,FOS,SLC25A11,EWSR1,HSPA8,SLC39A7,EP300,BAG2,TUBB4B,MAP2K1,NFE2L2,SSR1,KLF4,STK16,SLC25A3,MAPK10,MAP2K3 |
| 4.988e-02 | -3.00 | ESS2 (ess-2 splicing factor homolog) | protein interactions | 8220 | 138 | 48 | 19454 | 5460 |
UTP6,XPO1,FRA10AC1,PRPF19,CHCHD1,CDK5RAP3,CDC5L,EGLN3,THOC1,PRNP,SNRPA1,HINT3,TP53,SNRPE,CBX3,GALC,BAG2,EWSR1,SNIP1,SNRPG,PFDN1,ASF1A,TSSC4,ACADS,DHX16,KRAS,HNRNPC,MYC,RIT1,ARMC7,EXOC8,ELAVL2,ZNF330,CCNF,MAD2L1,SNRNP40,RALYL,SNRPN,LMNA,RPA2,NUP50,HSPA8,PML,NKAPD1,RPA3,COIL,OIP5,RBM22 |
| 4.988e-02 | -3.00 | STAM2 (signal transducing adaptor molecule 2) | protein interactions | 10254 | 138 | 48 | 19454 | 5460 |
TMT1A,NTRK2,JAK1,EPHA4,RIGI,FLOT1,TP53,KBTBD4,TIMM8A,EZH2,HGS,FURIN,PTPN1,KRT8,TSG101,GJA1,CAV1,STX6,DIRAS3,LCP2,DPP4,XPO1,YWHAG,YWHAH,UBE2D1,RHOU,ARRDC3,USP8,UBE2D3,LITAF,RNF11,BET1,FGFR1,STAMBP,CCNF,CDC7,RHOJ,JAK2,CBX5,SEC13,DNAJC5,RHOB,LAMTOR1,UBE2H,NAPA,NRP1,NTRK3,EPHA2 |
| 4.988e-02 | -3.00 | GPS2 (G protein pathway suppressor 2) | protein interactions | 2874 | 138 | 48 | 19454 | 5460 |
KRAS,PAX6,MAEA,ACTR1B,MKLN1,SUPT5H,TP53,SOX2,SMUG1,SPPL3,EGLN3,UBTD2,SIN3A,LDLR,PPFIA3,ARMC8,AKAP8L,CNOT2,XPO1,OIP5,HDAC3,RANBP10,FAM168B,GID8,DCTN6,GID4,ACTMAP,DCTN3,EP300,HDAC5,ATP5IF1,TRIM68,DCTN4,PPARG,KLF3,PAX9,TFIP11,DAPK3,KRTAP3-1,CREB1,SESTD1,CYTH1,YPEL5,PRMT6,ATF4,MYC,HNF1B,AR |
| 4.989e-02 | -3.00 | solitary_fibrous_tumour | COSMIC cancer mutations | solitary_fibrous_tumour | 32 | 14 | 16828 | 4835 |
FGFR1,TERT,NAB2,KIT,MET,CTNNB1,STX6,TP53,SS18,CLCA1,HRAS,KRAS,RNF103,IDH1 |
| 4.997e-02 | -3.00 | MED19 (mediator complex subunit 19) | protein interactions | 219541 | 103 | 37 | 19454 | 5460 |
MAD2L1,POLR2B,MED17,POLR2I,DCK,POLR2F,POLR2L,NFKBIA,GTF2B,BRD3,TADA1,MED4,SMAD2,MED29,MED10,MED21,MED27,MED22,PRDX1,MSX1,FBXW7,MED11,MED13L,DHRS7B,HECTD1,MED31,POLR2D,POLR2G,POLR2C,CDK8,MED23,SMAD1,MED30,FBXL19,RPAP2,MED9,RAF1 |
| 4.997e-02 | -3.00 | HJURP (Holliday junction recognition protein) | protein interactions | 55355 | 103 | 37 | 19454 | 5460 |
EED,MYBL2,LURAP1,SRSF1,STT3A,ESR2,EGLN3,BRMS1L,TUBB,RBBP4,ACTL6B,YWHAH,YWHAG,RPL7A,MOV10,RIT1,YWHAB,RPS2,FBXW11,YWHAZ,BAG2,RUVBL2,RPL3,PTGES3,PHF1,MBD3,RUVBL1,OIP5,RBBP7,NPM3,SAP30,SOX2,MTA3,MTA2,NOL7,HDAC11,CDK1 |
| 4.997e-02 | -3.00 | MIR19B1 (microRNA 19b-1) | protein interactions | 406980 | 103 | 37 | 19454 | 5460 |
CPSF4,SF3A1,RBFOX2,RBMS2,P3H1,WWP1,HNRNPH3,RARS1,HNRNPA2B1,SF3B1,HNRNPH2,RTCB,HNRNPF,TRA2B,HNRNPA0,HNRNPK,G3BP2,MARS1,KARS1,APOBEC3B,WWP2,HNRNPA1,NONO,CPSF2,TRA2A,CRTAP,DDX1,IGF2BP1,CPSF1,SYNCRIP,EIF2AK2,MYEF2,SF3B4,MATR3,HNRNPL,FAM98A,CSTF3 |
| 4.997e-02 | -3.00 | ID2 (inhibitor of DNA binding 2) | protein interactions | 3398 | 103 | 37 | 19454 | 5460 |
E2F4,ELK4,WBP11,ID4,TUBB4B,FRS3,CDK1,RHOU,SQSTM1,CFDP1,RNF113A,PICK1,HSPA8,STK38,KDM1A,HSPA5,ENKD1,GFUS,PRMT6,DYRK1B,IFI16,FNDC11,SUV39H1,ELOC,DCAF4,RBM27,TUBA1B,ELK3,SIN3A,RB1,ADD1,PRMT5,TUBB,FZR1,DYRK1A,ELK1,LRIF1 |