TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
myc_activpathway	Validated targets of C-MYC transcriptional activation	1.53894125071553e-05	-11.0818307845162	81	47	0.0601023017902813	782	2226	4318,2597,891,4088,1965,4609,3658,4149,92140,7015,57678,6880,84864,7037,4953,6513,5274,2033,581,8464,3159,4089,3939,1019,6881,11235,10075,2023,9913,5366,10856,4831,1977,80177,6470,332,91942,3320,8607,86,4830,23089,3329,10935,1387,4683,7157	MMP9,GAPDH,CCNB1,SMAD3,EIF2S1,MYC,IREB2,MAX,MTDH,TERT,GPAM,TAF9,RIOX2,TFRC,ODC1,SLC2A1,SERPINI1,EP300,BAX,SUPT3H,HMGA1,SMAD4,LDHA,CDK4,TAF10,PDCD10,HUWE1,ENO1,SUPT7L,PMAIP1,RUVBL2,NME2,EIF4E,MYCT1,SHMT1,BIRC5,NDUFAF2,HSP90AA1,RUVBL1,ACTL6A,NME1,PEG10,HSPD1,PRDX3,CREBBP,NBN,TP53
il2_stat5pathway	IL2 signaling events mediated by STAT5	9.58560864055713e-05	-9.25266259121296	30	21	0.0268542199488491	782	2226	5290,1021,6776,6667,6464,896,1997,890,3716,5295,4609,5781,356,4049,3558,3560,3559,3565,598,50943,3561	PIK3CA,CDK6,STAT5A,SP1,SHC1,CCND3,ELF1,CCNA2,JAK1,PIK3R1,MYC,PTPN11,FASLG,LTA,IL2,IL2RB,IL2RA,IL4,BCL2L1,FOXP3,IL2RG
ar_nongenomic_pathway	Nongenotropic Androgen signaling	0.000259498671416179	-8.25675897515495	18	14	0.0179028132992327	782	2226	54331,3265,207,367,5894,2353,6714,1385,5290,27043,2782,5295,2796,5604	GNG2,HRAS,AKT1,AR,RAF1,FOS,SRC,CREB1,PIK3CA,PELP1,GNB1,PIK3R1,GNRH1,MAP2K1
reg_gr_pathway	Glucocorticoid receptor regulatory network	0.00168493107918466	-6.38603061857538	82	42	0.0537084398976982	782	2226	1385,6613,1958,3569,5536,2288,5602,2033,581,6772,3567,1437,5617,3725,3458,1387,632,7533,7157,3659,8851,3596,3565,51111,5449,5567,3576,6776,2353,4790,1020,4193,2810,7251,7433,5106,3558,1026,9970,207,3383,3320	CREB1,SUMO2,EGR1,IL6,PPP5C,FKBP4,MAPK10,EP300,BAX,STAT1,IL5,CSF2,PRL,JUN,IFNG,CREBBP,BGLAP,YWHAH,TP53,IRF1,CDK5R1,IL13,IL4,KMT5B,POU1F1,PRKACB,CXCL8,STAT5A,FOS,NFKB1,CDK5,MDM2,SFN,TSG101,VIPR1,PCK2,IL2,CDKN1A,NR1I3,AKT1,ICAM1,HSP90AA1
smad2_3nuclearpathway	Regulation of nuclear SMAD2/3 signaling	0.00476696525680941	-5.34604539105758	76	38	0.0485933503836317	782	2226	1019,3725,7709,1387,3665,3456,1487,60436,865,2033,3312,1385,4087,4089,7421,3567,1026,3693,4149,10284,207,467,1745,7030,8819,5928,3586,367,4435,1278,4208,2353,79753,25942,5931,6667,4609,4088	CDK4,JUN,ZBTB17,CREBBP,IRF7,IFNB1,CTBP1,TGIF2,CBFB,EP300,HSPA8,CREB1,SMAD2,SMAD4,VDR,IL5,CDKN1A,ITGB5,MAX,SAP18,AKT1,ATF3,DLX1,TFE3,SAP30,RBBP4,IL10,AR,CITED1,COL1A2,MEF2C,FOS,SNIP1,SIN3A,RBBP7,SP1,MYC,SMAD3
il23pathway	IL23-mediated signaling events	0.00545316207111286	-5.21155964202145	37	21	0.0268542199488491	782	2226	3593,3553,112744,51561,3458,3558,4283,4792,9021,3569,3606,6347,5290,2919,6776,7124,5295,3717,4790,6772,920	IL12B,IL1B,IL17F,IL23A,IFNG,IL2,CXCL9,NFKBIA,SOCS3,IL6,IL18,CCL2,PIK3CA,CXCL1,STAT5A,TNF,PIK3R1,JAK2,NFKB1,STAT1,CD4
il1pathway	IL1-mediated signaling events	0.00599711752977193	-5.11647633689344	35	20	0.0255754475703325	782	2226	10454,54472,4790,3551,5295,5290,7335,7850,5608,51135,7189,4215,8878,4615,23118,353376,3725,3552,7334,3553	TAB1,TOLLIP,NFKB1,IKBKB,PIK3R1,PIK3CA,UBE2V1,IL1R2,MAP2K6,IRAK4,TRAF6,MAP3K3,SQSTM1,MYD88,TAB2,TICAM2,JUN,IL1A,UBE2N,IL1B
ecadherin_nascentaj_pathway	E-cadherin signaling in the nascent adherens junction	0.00658414695824054	-5.02309049534606	33	19	0.0242966751918159	782	2226	1500,26999,595,10787,207,8907,1499,3728,7410,1495,7074,1739,998,5295,5290,6714,382,2017,4830	CTNND1,CYFIP2,CCND1,NCKAP1,AKT1,AP1M1,CTNNB1,JUP,VAV2,CTNNA1,TIAM1,DLG1,CDC42,PIK3R1,PIK3CA,SRC,ARF6,CTTN,NME1
hif2pathway	HIF-2-alpha transcription factor network	0.0101080157442189	-4.59442653185759	34	19	0.0242966751918159	782	2226	4891,2395,9429,2056,5460,8553,1387,7422,5230,112399,4323,2002,328,6667,6513,6921,3646,112398,2033	SLC11A2,FXN,ABCG2,EPO,POU5F1,BHLHE40,CREBBP,VEGFA,PGK1,EGLN3,MMP14,ELK1,APEX1,SP1,SLC2A1,ELOC,EIF3E,EGLN2,EP300
er_nongenomic_pathway	Plasma membrane estrogen receptor signaling	0.0150158278933862	-4.19865044131221	26	15	0.0191815856777494	782	2226	9475,5295,23236,4478,6714,4318,5290,27043,2782,3480,207,2100,5330,1839,54331	ROCK2,PIK3R1,PLCB1,MSN,SRC,MMP9,PIK3CA,PELP1,GNB1,IGF1R,AKT1,ESR2,PLCB2,HBEGF,GNG2
ifngpathway	IFN-gamma pathway	0.0172037216195367	-4.06262954533916	40	21	0.0268542199488491	782	2226	6772,5604,1612,5295,3716,3717,5781,5290,10379,2033,818,8554,1399,207,867,1387,4296,3458,3659,3553,3459	STAT1,MAP2K1,DAPK1,PIK3R1,JAK1,JAK2,PTPN11,PIK3CA,IRF9,EP300,CAMK2G,PIAS1,CRKL,AKT1,CBL,CREBBP,MAP3K11,IFNG,IRF1,IL1B,IFNGR1
myc_pathway	C-MYC pathway	0.0180793328628326	-4.01298582387851	22	13	0.0166240409207161	782	2226	10856,4609,8464,86,26959,8607,9913,6880,5062,6881,7709,5525,4149	RUVBL2,MYC,SUPT3H,ACTL6A,HBP1,RUVBL1,SUPT7L,TAF9,PAK2,TAF10,ZBTB17,PPP2R5A,MAX
pdgfrapathway	PDGFR-alpha signaling pathway	0.0180793328628326	-4.01298582387851	22	13	0.0166240409207161	782	2226	1457,1399,857,3725,3458,2002,3685,5295,3716,5290,6464,2353,859	CSNK2A1,CRKL,CAV1,JUN,IFNG,ELK1,ITGAV,PIK3R1,JAK1,PIK3CA,SHC1,FOS,CAV3
kitpathway	Signaling events mediated by Stem cell factor receptor (c-Kit)	0.0182810918108907	-4.00188798766693	52	26	0.0332480818414322	782	2226	867,4286,572,1387,9402,6772,5604,26228,5781,3717,5290,5728,6464,3815,6591,1399,207,2056,2887,2549,161742,3265,200734,5295,6776,5894	CBL,MITF,BAD,CREBBP,GRAP2,STAT1,MAP2K1,STAP1,PTPN11,JAK2,PIK3CA,PTEN,SHC1,KIT,SNAI2,CRKL,AKT1,EPO,GRB10,GAB1,SPRED1,HRAS,SPRED2,PIK3R1,STAT5A,RAF1
il6_7pathway	IL6-mediated signaling events	0.0213137380963121	-3.84840343313012	43	22	0.0281329923273657	782	2226	5290,3569,6772,3572,8543,5781,3717,3725,4286,7184,3659,3726,4170,5608,2353,7076,3716,5295,4609,9021,8554,207	PIK3CA,IL6,STAT1,IL6ST,LMO4,PTPN11,JAK2,JUN,MITF,HSP90B1,IRF1,JUNB,MCL1,MAP2K6,FOS,TIMP1,JAK1,PIK3R1,MYC,SOCS3,PIAS1,AKT1
tcr_pathway	TCR signaling in naive CD4+ T cells	0.0225065526582898	-3.79394878291345	60	29	0.0370843989769821	782	2226	998,920,942,5579,5581,941,940,84174,5906,207,917,6786,1445,5781,3551,3702,919,6464,5728,4690,5578,8915,3937,867,10235,5588,7189,9402,9020	CDC42,CD4,CD86,PRKCB,PRKCE,CD80,CD28,SLA2,RAP1A,AKT1,CD3G,STIM1,CSK,PTPN11,IKBKB,ITK,CD247,SHC1,PTEN,NCK1,PRKCA,BCL10,LCP2,CBL,RASGRP2,PRKCQ,TRAF6,GRAP2,MAP3K14
nfat_tfpathway	Calcineurin-regulated NFAT-dependent transcription in lymphocytes	0.0229538853866633	-3.77426805891103	48	24	0.030690537084399	782	2226	356,3558,1493,50943,5770,3576,3726,7124,1959,2353,5468,3725,3458,1019,3559,3565,959,5588,3662,1958,3562,79589,3567,1437	FASLG,IL2,CTLA4,FOXP3,PTPN1,CXCL8,JUNB,TNF,EGR2,FOS,PPARG,JUN,IFNG,CDK4,IL2RA,IL4,CD40LG,PRKCQ,IRF4,EGR1,IL3,RNF128,IL5,CSF2
cxcr3pathway	CXCR3-mediated signaling events	0.0241141257602051	-3.72495747906444	34	18	0.0230179028132992	782	2226	2833,5604,3627,6373,5606,5295,2782,5290,6714,2771,5894,5608,6356,4283,2773,207,54331,10563	CXCR3,MAP2K1,CXCL10,CXCL11,MAP2K3,PIK3R1,GNB1,PIK3CA,SRC,GNAI2,RAF1,MAP2K6,CCL11,CXCL9,GNAI3,AKT1,GNG2,CXCL13
pi3kplctrkpathway	Trk receptor signaling mediated by PI3K and PLC-gamma	0.0270052265442023	-3.61172485599997	32	17	0.0217391304347826	782	2226	207,7534,595,7532,7529,2810,2549,7533,572,116986,5295,6464,1385,6714,1958,5290,6776	AKT1,YWHAZ,CCND1,YWHAG,YWHAB,SFN,GAB1,YWHAH,BAD,AGAP2,PIK3R1,SHC1,CREB1,SRC,EGR1,PIK3CA,STAT5A
il12_2pathway	IL12-mediated signaling events	0.0289296841164133	-3.54288707894713	61	29	0.0370843989769821	782	2226	6772,6348,3717,4616,56848,919,1234,3606,3565,3561,567,3458,3559,3553,10912,4790,6778,920,5606,6776,5608,2353,388372,917,356,3592,3558,3593,3560	STAT1,CCL3,JAK2,GADD45B,SPHK2,CD247,CCR5,IL18,IL4,IL2RG,B2M,IFNG,IL2RA,IL1B,GADD45G,NFKB1,STAT6,CD4,MAP2K3,STAT5A,MAP2K6,FOS,CCL4L1,CD3G,FASLG,IL12A,IL2,IL12B,IL2RB
telomerasepathway	Regulation of Telomerase	0.029414872906779	-3.52625485136929	66	31	0.0396419437340153	782	2226	8819,3320,10284,207,5928,7015,7337,3558,4149,4609,4088,4790,1736,2353,10038,5931,6667,25942,595,1027,8658,3659,3458,4683,3725,23381,3183,4084,10728,7520,5810	SAP30,HSP90AA1,SAP18,AKT1,RBBP4,TERT,UBE3A,IL2,MAX,MYC,SMAD3,NFKB1,DKC1,FOS,PARP2,RBBP7,SP1,SIN3A,CCND1,CDKN1B,TNKS,IRF1,IFNG,NBN,JUN,SMG5,HNRNPC,MXD1,PTGES3,XRCC5,RAD1
cd40_pathway	CD40/CD40L signaling	0.03025462226807	-3.49810630392811	30	16	0.020460358056266	782	2226	7186,3725,9020,4792,207,3565,958,7189,959,5602,7185,6776,4609,329,7128,4790	TRAF2,JUN,MAP3K14,NFKBIA,AKT1,IL4,CD40,TRAF6,CD40LG,MAPK10,TRAF1,STAT5A,MYC,BIRC2,TNFAIP3,NFKB1
erbb1_downstream_pathway	ErbB1 downstream signaling	0.034251620443661	-3.37402140316941	102	45	0.0575447570332481	782	2226	1843,5868,10787,10097,207,2549,7529,2002,7410,4609,5295,4086,2353,5518,5894,7533,2059,10109,10094,5898,378,6772,1958,5536,5037,2810,466,998,6714,4208,7534,26999,9712,1848,572,1124,3725,824,7532,8976,5604,8986,5578,5290,1385	DUSP1,RAB5A,NCKAP1,ACTR2,AKT1,GAB1,YWHAB,ELK1,VAV2,MYC,PIK3R1,SMAD1,FOS,PPP2R1A,RAF1,YWHAH,EPS8,ARPC2,ARPC3,RALA,ARF4,STAT1,EGR1,PPP5C,PEBP1,SFN,ATF1,CDC42,SRC,MEF2C,YWHAZ,CYFIP2,USP6NL,DUSP6,BAD,CHN2,JUN,CAPN2,YWHAG,WASL,MAP2K1,RPS6KA4,PRKCA,PIK3CA,CREB1
il27pathway	IL27-mediated signaling events	0.0380216267173058	-3.26960015700585	26	14	0.0179028132992327	782	2226	3558,3592,3458,3553,3593,3572,6772,3717,6773,3716,7124,6776,3606,3569	IL2,IL12A,IFNG,IL1B,IL12B,IL6ST,STAT1,JAK2,STAT2,JAK1,TNF,STAT5A,IL18,IL6
atf2_pathway	ATF-2 transcription factor network	0.0404724446029629	-3.20713391660703	55	26	0.0332480818414322	782	2226	3726,7042,3576,2353,890,10856,1843,9021,467,5578,1385,11221,2033,865,1647,3569,1649,43,51561,3458,9555,672,3725,8452,1019,595	JUNB,TGFB2,CXCL8,FOS,CCNA2,RUVBL2,DUSP1,SOCS3,ATF3,PRKCA,CREB1,DUSP10,EP300,CBFB,GADD45A,IL6,DDIT3,ACHE,IL23A,IFNG,MACROH2A1,BRCA1,JUN,CUL3,CDK4,CCND1
a6b1_a6b4_integrin_pathway	a6b1 and a6b4 Integrin signaling	0.0426872159949207	-3.15385579479371	31	16	0.020460358056266	782	2226	5295,4233,3655,6464,5290,5376,5578,207,7534,7529,7532,928,3265,3552,2810,7533	PIK3R1,MET,ITGA6,SHC1,PIK3CA,PMP22,PRKCA,AKT1,YWHAZ,YWHAB,YWHAG,CD9,HRAS,IL1A,SFN,YWHAH
p53downstreampathway	Direct p53 effectors	0.0443386371572585	-3.11589881145807	132	56	0.0716112531969309	782	2226	6376,578,57060,29108,7832,5366,4233,55800,54487,6696,2810,1969,51065,1026,22943,4068,25898,5728,5925,6591,1434,54541,1509,7421,1387,3725,64326,7157,3486,6667,355,4170,5564,604,1655,891,4193,4800,1843,28984,467,6880,255488,9540,597,1647,581,2033,5111,4801,665,2876,94241,5371,29102,857	CX3CL1,BAK1,PCBP4,PYCARD,BTG2,PMAIP1,MET,SCN3B,DGCR8,SPP1,SFN,EPHA2,RPS27L,CDKN1A,DKK1,SH2D1A,RCHY1,PTEN,RB1,SNAI2,CSE1L,DDIT4,CTSD,VDR,CREBBP,JUN,COP1,TP53,IGFBP3,SP1,FAS,MCL1,PRKAB1,BCL6,DDX5,CCNB1,MDM2,NFYA,DUSP1,RGCC,ATF3,TAF9,RNF144B,TP53I3,BCL2A1,GADD45A,BAX,EP300,PCNA,NFYB,BNIP3L,GPX1,TP53INP1,PML,DROSHA,CAV1
foxopathway	FoxO family signaling	0.04440924562584	-3.1143075964056	48	23	0.0294117647058824	782	2226	3551,891,604,5901,2033,5602,6648,1647,114907,207,1454,7534,1456,7529,1499,7532,1027,356,2810,1452,1387,7514,7533	IKBKB,CCNB1,BCL6,RAN,EP300,MAPK10,SOD2,GADD45A,FBXO32,AKT1,CSNK1E,YWHAZ,CSNK1G3,YWHAB,CTNNB1,YWHAG,CDKN1B,FASLG,SFN,CSNK1A1,CREBBP,XPO1,YWHAH
alk2pathway	ALK2 signaling events	0.0507074598321414	-2.98168224247992	11	7	0.00895140664961637	782	2226	4086,2280,90,659,4093,4090,4089	SMAD1,FKBP1A,ACVR1,BMPR2,SMAD9,SMAD5,SMAD4
rb_1pathway	Regulation of retinoblastoma protein	0.0511169074612516	-2.97363996641471	56	26	0.0332480818414322	782	2226	7042,8841,5894,4208,4233,890,5468,4193,1026,5948,5928,6441,6598,5925,26574,2033,1997,1437,3725,4286,1387,632,1027,1874,6839,1487	TGFB2,HDAC3,RAF1,MEF2C,MET,CCNA2,PPARG,MDM2,CDKN1A,RBP2,RBBP4,SFTPD,SMARCB1,RB1,AATF,EP300,ELF1,CSF2,JUN,MITF,CREBBP,BGLAP,CDKN1B,E2F4,SUV39H1,CTBP1
myc_represspathway	Validated targets of C-MYC transcriptional repression	0.05116411698959	-2.97271683268694	61	28	0.0358056265984655	782	2226	8841,1791,1278,2966,6667,4800,4609,6422,1026,4149,22943,4801,1647,2033,1385,4089,1649,3655,1027,3394,84233,7709,2495,2672,1191,6352,672,595	HDAC3,DNTT,COL1A2,GTF2H2,SP1,NFYA,MYC,SFRP1,CDKN1A,MAX,DKK1,NFYB,GADD45A,EP300,CREB1,SMAD4,DDIT3,ITGA6,CDKN1B,IRF8,TMEM126A,ZBTB17,FTH1,GFI1,CLU,CCL5,BRCA1,CCND1
pi3kciaktpathway	Class I PI3K signaling events mediated by Akt	0.0517967902623262	-2.96042709568431	34	17	0.0217391304347826	782	2226	7533,572,2931,2810,1027,7529,7532,1026,9882,7534,3836,3320,207,10000,6714,208,5894	YWHAH,BAD,GSK3A,SFN,CDKN1B,YWHAB,YWHAG,CDKN1A,TBC1D4,YWHAZ,KPNA1,HSP90AA1,AKT1,AKT3,SRC,AKT2,RAF1
hdac_classii_pathway	Signaling events mediated by HDAC Class II	0.0517967902623262	-2.96042709568431	34	17	0.0217391304347826	782	2226	57763,7514,7529,79885,54331,3320,7329,8625,10013,2782,8841,4208,604,10376,5901,7341,10014	ANKRA2,XPO1,YWHAB,HDAC11,GNG2,HSP90AA1,UBE2I,RFXANK,HDAC6,GNB1,HDAC3,MEF2C,BCL6,TUBA1B,RAN,SUMO1,HDAC5
hedgehog_glipathway	Hedgehog signaling events mediated by Gli proteins	0.0558913170069088	-2.8843462417107	44	21	0.0268542199488491	782	2226	51715,5931,2782,25942,3958,23291,5604,54331,51684,7514,8405,1387,1452,8819,10284,1454,207,8554,1456,5928,26160	RAB23,RBBP7,GNB1,SIN3A,LGALS3,FBXW11,MAP2K1,GNG2,SUFU,XPO1,SPOP,CREBBP,CSNK1A1,SAP30,SAP18,CSNK1E,AKT1,PIAS1,CSNK1G3,RBBP4,IFT172
arf6_traffickingpathway	Arf6 trafficking events	0.0558913170069088	-2.8843462417107	44	21	0.0268542199488491	782	2226	3728,3655,7253,1495,966,5898,1363,3673,55770,382,10066,1785,9341,4830,11336,55763,1500,154,10640,1499,3559	JUP,ITGA6,TSHR,CTNNA1,CD59,RALA,CPE,ITGA2,EXOC2,ARF6,SCAMP2,DNM2,VAMP3,NME1,EXOC3,EXOC1,CTNND1,ADRB2,EXOC5,CTNNB1,IL2RA
p38alphabetadownstreampathway	Signaling mediated by p38-alpha and p38-beta	0.0688171105724227	-2.67630286478304	35	17	0.0217391304347826	782	2226	5868,3315,4205,1977,2005,3725,4286,7157,466,1649,3856,7867,8986,1385,8550,26959,4208	RAB5A,HSPB1,MEF2A,EIF4E,ELK4,JUN,MITF,TP53,ATF1,DDIT3,KRT8,MAPKAPK3,RPS6KA4,CREB1,MAPKAPK5,HBP1,MEF2C
nfkappabcanonicalpathway	Canonical NF-kappaB pathway	0.0690150534535781	-2.67343063218573	23	12	0.0153452685421995	782	2226	5578,7124,8915,5901,4790,3551,329,7128,7514,7189,4792,7323	PRKCA,TNF,BCL10,RAN,NFKB1,IKBKB,BIRC2,TNFAIP3,XPO1,TRAF6,NFKBIA,UBE2D3
hif1_tfpathway	HIF-1-alpha transcription factor network	0.0692003248319744	-2.67074972226585	65	29	0.0370843989769821	782	2226	10987,2033,1385,7018,7037,5045,3952,6513,4089,112399,3725,3939,1387,7422,9429,6387,4170,2353,2023,6667,5243,4088,5236,5230,7852,8553,207,2056,7015	COPS5,EP300,CREB1,TF,TFRC,FURIN,LEP,SLC2A1,SMAD4,EGLN3,JUN,LDHA,CREBBP,VEGFA,ABCG2,CXCL12,MCL1,FOS,ENO1,SP1,ABCB1,SMAD3,PGM1,PGK1,CXCR4,BHLHE40,AKT1,EPO,TERT
il4_2pathway	IL4-mediated signaling events	0.0702377892065908	-2.65586880499984	60	27	0.0345268542199488	782	2226	9655,959,3565,867,3561,6361,5290,3662,6464,3159,3567,3717,7070,4049,9021,6356,3586,207,6667,6776,1959,4988,1278,604,6778,3716,5295	SOCS5,CD40LG,IL4,CBL,IL2RG,CCL17,PIK3CA,IRF4,SHC1,HMGA1,IL5,JAK2,THY1,LTA,SOCS3,CCL11,IL10,AKT1,SP1,STAT5A,EGR2,OPRM1,COL1A2,BCL6,STAT6,JAK1,PIK3R1
cd8tcrdownstreampathway	Downstream signaling in naive CD8+ T cells	0.071392060100731	-2.63956861889111	50	23	0.0294117647058824	782	2226	3561,5588,3559,3458,3725,567,5604,919,5578,1958,917,3454,3560,3558,356,2002,5581,5579,2353,5894,7124,3604,3726	IL2RG,PRKCQ,IL2RA,IFNG,JUN,B2M,MAP2K1,CD247,PRKCA,EGR1,CD3G,IFNAR1,IL2RB,IL2,FASLG,ELK1,PRKCE,PRKCB,FOS,RAF1,TNF,TNFRSF9,JUNB
s1p_s1p3_pathway	S1P3 pathway	0.0743873684683626	-2.59846913020816	28	14	0.0179028132992327	782	2226	3717,9630,3685,2771,6714,2775,10000,2773,2781,207,2767,2776,7852,7422	JAK2,GNA14,ITGAV,GNAI2,SRC,GNAO1,AKT3,GNAI3,GNAZ,AKT1,GNA11,GNAQ,CXCR4,VEGFA
epopathway	EPO signaling pathway	0.0775821442077245	-2.55641797868605	33	16	0.020460358056266	782	2226	6776,6464,4790,6772,7410,3717,5781,5295,2549,3265,9021,598,2056,5906,867,1399	STAT5A,SHC1,NFKB1,STAT1,VAV2,JAK2,PTPN11,PIK3R1,GAB1,HRAS,SOCS3,BCL2L1,EPO,RAP1A,CBL,CRKL
cd8tcrpathway	TCR signaling in naive CD8+ T cells	0.0798464213406193	-2.52765022260009	48	22	0.0281329923273657	782	2226	942,5581,5579,940,941,6786,917,207,5906,1445,3551,5578,8915,919,5588,7189,3937,10235,867,9020,567,9402	CD86,PRKCE,PRKCB,CD28,CD80,STIM1,CD3G,AKT1,RAP1A,CSK,IKBKB,PRKCA,BCL10,CD247,PRKCQ,TRAF6,LCP2,RASGRP2,CBL,MAP3K14,B2M,GRAP2
hdac_classi_pathway	Signaling events mediated by HDAC Class I	0.0835271323779806	-2.48258376124801	66	29	0.0370843989769821	782	2226	25942,7024,5931,7124,8841,4790,5468,4149,7514,57154,79885,10419,5928,10284,8819,10013,51547,2033,4084,23381,5901,7341,10014,79084,1387,53615,7329,4792,9219	SIN3A,TFCP2,RBBP7,TNF,HDAC3,NFKB1,PPARG,MAX,XPO1,SMURF1,HDAC11,PRMT5,RBBP4,SAP18,SAP30,HDAC6,SIRT7,EP300,MXD1,SMG5,RAN,SUMO1,HDAC5,WDR77,CREBBP,MBD3,UBE2I,NFKBIA,MTA2
tcptp_pathway	Signaling events mediated by TCPTP	0.089223178137761	-2.4166144285562	36	17	0.0217391304347826	782	2226	6772,4233,6778,5295,3716,5290,6714,6776,3998,8554,5770,5610,5867,1387,7422,2549,3838	STAT1,MET,STAT6,PIK3R1,JAK1,PIK3CA,SRC,STAT5A,LMAN1,PIAS1,PTPN1,EIF2AK2,RAB4A,CREBBP,VEGFA,GAB1,KPNA2
alk1pathway	ALK1 signaling events	0.0953774959622419	-2.34991261973576	24	12	0.0153452685421995	782	2226	659,4093,4089,4086,7048,90,7043,4090,857,3397,2280,1460	BMPR2,SMAD9,SMAD4,SMAD1,TGFBR2,ACVR1,TGFB3,SMAD5,CAV1,ID1,FKBP1A,CSNK2B
mapktrkpathway	Trk receptor signaling mediated by the MAPK pathway	0.0989665599441041	-2.31297326424988	29	14	0.0179028132992327	782	2226	5604,2002,1020,5606,30844,1385,1958,2353,4208,5894,5608,8851,6016,6014	MAP2K1,ELK1,CDK5,MAP2K3,EHD4,CREB1,EGR1,FOS,MEF2C,RAF1,MAP2K6,CDK5R1,RIT1,RIT2
fra_pathway	Validated transcriptional targets of AP1 family members Fra1 and Fra2	0.100502458826123	-2.29757308585072	34	16	0.020460358056266	782	2226	632,4256,3725,7056,595,9988,6667,4318,3726,3576,2697,6347,2033,1278,3569,890	BGLAP,MGP,JUN,THBD,CCND1,DMTF1,SP1,MMP9,JUNB,CXCL8,GJA1,CCL2,EP300,COL1A2,IL6,CCNA2
syndecan_3_pathway	Syndecan-3-mediated signaling events	0.100585023161702	-2.29675190753169	17	9	0.0115089514066496	782	2226	51107,3576,6714,23385,2017,55851,5663,5764,8573	APH1A,CXCL8,SRC,NCSTN,CTTN,PSENEN,PSEN1,PTN,CASK
il2_1pathway	IL2-mediated signaling events	0.107850620527966	-2.22700815254307	52	23	0.0294117647058824	782	2226	6464,5290,5781,8835,6772,5604,3559,3725,3458,3561,5894,2353,5579,5581,1154,6776,5295,3716,4609,3560,3558,6850,9021	SHC1,PIK3CA,PTPN11,SOCS2,STAT1,MAP2K1,IL2RA,JUN,IFNG,IL2RG,RAF1,FOS,PRKCB,PRKCE,CISH,STAT5A,PIK3R1,JAK1,MYC,IL2RB,IL2,SYK,SOCS3
fgf_pathway	FGF signaling pathway	0.11011082491074	-2.20626792118785	47	21	0.0268542199488491	782	2226	5295,5781,6772,4233,6464,2353,5290,4318,6714,2017,2260,8074,207,867,1500,6383,6696,2246,3725,2549,632	PIK3R1,PTPN11,STAT1,MET,SHC1,FOS,PIK3CA,MMP9,SRC,CTTN,FGFR1,FGF23,AKT1,CBL,CTNND1,SDC2,SPP1,FGF1,JUN,GAB1,BGLAP
lysophospholipid_pathway	LPA receptor mediated events	0.110261639297575	-2.20489919836741	65	28	0.0358056265984655	782	2226	9630,4790,5295,6714,4318,2775,3576,2782,2771,2353,5581,9170,2767,207,2773,2781,109,2549,3265,7074,3569,1902,108,4792,3725,2776,1839,54331	GNA14,NFKB1,PIK3R1,SRC,MMP9,GNAO1,CXCL8,GNB1,GNAI2,FOS,PRKCE,LPAR2,GNA11,AKT1,GNAI3,GNAZ,ADCY3,GAB1,HRAS,TIAM1,IL6,LPAR1,ADCY2,NFKBIA,JUN,GNAQ,HBEGF,GNG2
p38alphabetapathway	Regulation of p38-alpha and p38-beta	0.112023256586181	-2.18904878115203	27	13	0.0166240409207161	782	2226	11221,7786,6714,5062,5608,2268,7525,7189,1843,10454,5606,4215,83605	DUSP10,MAP3K12,SRC,PAK2,MAP2K6,FGR,YES1,TRAF6,DUSP1,TAB1,MAP2K3,MAP3K3,CCM2
il2_pi3kpathway	IL2 signaling events mediated by PI3K	0.113123435354901	-2.17927570817459	37	17	0.0217391304347826	782	2226	3320,3561,207,598,7015,3560,3559,3558,5295,3716,5781,4609,4790,6464,5290,259230,7357	HSP90AA1,IL2RG,AKT1,BCL2L1,TERT,IL2RB,IL2RA,IL2,PIK3R1,JAK1,PTPN11,MYC,NFKB1,SHC1,PIK3CA,SGMS1,UGCG
avb3_opn_pathway	Osteopontin-mediated events	0.113327729101422	-2.17747140036779	32	15	0.0191815856777494	782	2226	4318,5290,2353,3685,998,4790,9475,5295,3611,6696,9020,3725,8394,4792,6850	MMP9,PIK3CA,FOS,ITGAV,CDC42,NFKB1,ROCK2,PIK3R1,ILK,SPP1,MAP3K14,JUN,PIP5K1A,NFKBIA,SYK
cxcr4_pathway	CXCR4-mediated signaling events	0.120931725949936	-2.11252914098104	76	32	0.040920716112532	782	2226	5330,7852,1072,1445,5908,207,917,2782,6776,6714,5996,4318,9525,920,7525,5899,5295,572,54331,2268,6387,9146,5290,919,3655,6772,3673,5781,27183,6773,3717,23236	PLCB2,CXCR4,CFL1,CSK,RAP1B,AKT1,CD3G,GNB1,STAT5A,SRC,RGS1,MMP9,VPS4B,CD4,YES1,RALB,PIK3R1,BAD,GNG2,FGR,CXCL12,HGS,PIK3CA,CD247,ITGA6,STAT1,ITGA2,PTPN11,VPS4A,STAT2,JAK2,PLCB1
erbb2erbb3pathway	ErbB2/ErbB3 signaling events	0.127184857355312	-2.06211368111145	35	16	0.020460358056266	782	2226	5604,5295,5781,3717,5290,6714,6464,5894,10193,5602,2353,4771,207,3725,572,9101	MAP2K1,PIK3R1,PTPN11,JAK2,PIK3CA,SRC,SHC1,RAF1,RNF41,MAPK10,FOS,NF2,AKT1,JUN,BAD,USP8
p75ntrpathway	p75(NTR)-mediated signaling	0.134620019526203	-2.00529913935276	61	26	0.0332480818414322	782	2226	5663,5295,28986,57142,4909,8878,55851,207,27018,4615,6610,4692,56160,3551,5045,5290,51107,5602,6464,7189,5340,23385,572,4974,11108,7157	PSEN1,PIK3R1,MAGEH1,RTN4,NTF4,SQSTM1,PSENEN,AKT1,BEX3,MYD88,SMPD2,NDN,NSMCE3,IKBKB,FURIN,PIK3CA,APH1A,MAPK10,SHC1,TRAF6,PLG,NCSTN,BAD,OMG,PRDM4,TP53
il12_stat4pathway	IL12 signaling mediated by STAT4	0.144641026288359	-1.93350028689636	28	13	0.0166240409207161	782	2226	917,3596,3659,3559,3725,3558,3458,1387,920,940,919,2353,3606	CD3G,IL13,IRF1,IL2RA,JUN,IL2,IFNG,CREBBP,CD4,CD28,CD247,FOS,IL18
tcrcalciumpathway	Calcium signaling in the CD4+ TCR pathway	0.144641026288359	-1.93350028689636	28	13	0.0166240409207161	782	2226	3559,2280,3558,3458,3725,356,3565,959,2353,3562,3726,1437,11261	IL2RA,FKBP1A,IL2,IFNG,JUN,FASLG,IL4,CD40LG,FOS,IL3,JUNB,CSF2,CHP1
igf1_pathway	IGF1 pathway	0.144641026288359	-1.93350028689636	28	13	0.0166240409207161	782	2226	5770,1399,207,7534,3265,572,2887,5781,5295,6464,3480,5894,5290	PTPN1,CRKL,AKT1,YWHAZ,HRAS,BAD,GRB10,PTPN11,PIK3R1,SHC1,IGF1R,RAF1,PIK3CA
met_pathway	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	0.145791309822641	-1.92557906459517	72	30	0.0383631713554987	782	2226	1499,5062,3265,1977,2549,207,1399,5770,57610,50855,5868,208,5894,382,6714,3636,5295,1495,4233,998,8976,3725,572,867,1958,5290,4690,9146,5781,5604	CTNNB1,PAK2,HRAS,EIF4E,GAB1,AKT1,CRKL,PTPN1,RANBP10,PARD6A,RAB5A,AKT2,RAF1,ARF6,SRC,INPPL1,PIK3R1,CTNNA1,MET,CDC42,WASL,JUN,BAD,CBL,EGR1,PIK3CA,NCK1,HGS,PTPN11,MAP2K1
ps1pathway	Presenilin action in Notch and Wnt signaling	0.148779190436727	-1.9052920155785	46	20	0.0255754475703325	782	2226	23291,10454,4609,5663,4040,2353,51107,3516,22943,595,1487,1457,7088,11197,55851,23385,1387,3725,1452,1499	FBXW11,TAB1,MYC,PSEN1,LRP6,FOS,APH1A,RBPJ,DKK1,CCND1,CTBP1,CSNK2A1,TLE1,WIF1,PSENEN,NCSTN,CREBBP,JUN,CSNK1A1,CTNNB1
ranbp2pathway	Sumoylation by RanBP2 regulates transcriptional repression	0.150323298244975	-1.89496698262632	11	6	0.00767263427109974	782	2226	4193,7329,5901,7341,7514,8554	MDM2,UBE2I,RAN,SUMO1,XPO1,PIAS1
tcrraspathway	Ras signaling in the CD4+ TCR pathway	0.150323298244975	-1.89496698262632	11	6	0.00767263427109974	782	2226	2353,5579,5894,5604,2002,5578	FOS,PRKCB,RAF1,MAP2K1,ELK1,PRKCA
arf6_pathway	Arf6 signaling events	0.176757762054759	-1.73297505972553	34	15	0.0191815856777494	782	2226	2767,9266,154,2776,26034,1969,4233,23527,7253,9630,9922,382,6714,4690,26269	GNA11,CYTH2,ADRB2,GNAQ,IPCEF1,EPHA2,MET,ACAP2,TSHR,GNA14,IQSEC1,ARF6,SRC,NCK1,FBXO8
vegfr1_pathway	VEGFR1 specific signals	0.181751530193295	-1.70511474338362	29	13	0.0166240409207161	782	2226	7422,8829,2549,207,867,3320,857,5290,4690,5578,23607,5295,5781	VEGFA,NRP1,GAB1,AKT1,CBL,HSP90AA1,CAV1,PIK3CA,NCK1,PRKCA,CD2AP,PIK3R1,PTPN11
lkb1_pathway	LKB1 signaling events	0.184362423091395	-1.6908517679563	42	18	0.0230179028132992	782	2226	7534,200186,6794,3320,51765,7533,2810,7529,7532,7157,51719,6604,1509,55437,4609,4089,1385,5664	YWHAZ,CRTC2,STK11,HSP90AA1,STK26,YWHAH,SFN,YWHAB,YWHAG,TP53,CAB39,SMARCD3,CTSD,STRADB,MYC,SMAD4,CREB1,PSEN2
nfkappabatypicalpathway	Atypical NF-kappaB pathway	0.185718629732608	-1.6835224939935	14	7	0.00895140664961637	782	2226	6714,5290,4790,5295,6850,3551,4792	SRC,PIK3CA,NFKB1,PIK3R1,SYK,IKBKB,NFKBIA
ecadherin_keratinocyte_pathway	E-cadherin signaling in keratinocytes	0.187829739772342	-1.67221936600023	19	9	0.0115089514066496	782	2226	5290,8394,6714,7791,208,1495,1500,207,5295	PIK3CA,PIP5K1A,SRC,ZYX,AKT2,CTNNA1,CTNND1,AKT1,PIK3R1
foxm1pathway	FOXM1 transcription factor network	0.191406212443632	-1.65335734258182	37	16	0.020460358056266	782	2226	983,255626,595,1163,332,1019,1387,2931,4609,5604,891,2033,2353,6667,4751,5925	CDK1,H2BC1,CCND1,CKS1B,BIRC5,CDK4,CREBBP,GSK3A,MYC,MAP2K1,CCNB1,EP300,FOS,SP1,NEK2,RB1
e2f_pathway	E2F transcription factor network	0.209387600126663	-1.5635681985041	72	29	0.0370843989769821	782	2226	2033,896,23468,26959,5925,5902,1027,1874,1387,4172,672,983,6240,1031,4170,6667,4609,7298,7029,11073,890,1026,221223,4605,1876,7030,5932,10419,5928	EP300,CCND3,CBX5,HBP1,RB1,RANBP1,CDKN1B,E2F4,CREBBP,MCM3,BRCA1,CDK1,RRM1,CDKN2C,MCL1,SP1,MYC,TYMS,TFDP2,TOPBP1,CCNA2,CDKN1A,CES5A,MYBL2,E2F6,TFE3,RBBP8,PRMT5,RBBP4
trkrpathway	Neurotrophic factor-mediated Trk receptor signaling	0.210113262396023	-1.5601085489158	56	23	0.0294117647058824	782	2226	6016,2549,4916,10287,6014,10817,55179,595,1399,4909,8878,5290,4915,30844,6464,9844,998,5604,7074,5295,53358,5781,391	RIT1,GAB1,NTRK3,RGS19,RIT2,FRS3,FAIM,CCND1,CRKL,NTF4,SQSTM1,PIK3CA,NTRK2,EHD4,SHC1,ELMO1,CDC42,MAP2K1,TIAM1,PIK3R1,SHC3,PTPN11,RHOG
epha2_fwdpathway	EPHA2 forward signaling	0.215338747552694	-1.53554292075017	17	8	0.010230179028133	782	2226	7410,7074,867,3636,5295,5290,6714,1969	VAV2,TIAM1,CBL,INPPL1,PIK3R1,PIK3CA,SRC,EPHA2
hnf3apathway	FOXA1 transcription factor network	0.218265405612377	-1.52204349975528	43	18	0.0230179028132992	782	2226	4824,367,6441,354,5265,672,1387,3725,1027,522,653509,3171,7494,6647,6667,1562,2353,2033	NKX3-1,AR,SFTPD,KLK3,SERPINA1,BRCA1,CREBBP,JUN,CDKN1B,ATP5PF,SFTPA1,FOXA3,XBP1,SOD1,SP1,CYP2C18,FOS,EP300
cdc42_pathway	CDC42 signaling events	0.228111164860643	-1.47792220367072	70	28	0.0358056265984655	782	2226	5608,5894,5581,6714,5295,5606,9459,7410,1495,7525,998,5062,1499,1072,3265,4296,10097,50855,5290,1739,7074,10094,8976,3725,10109,2059,5080,867	MAP2K6,RAF1,PRKCE,SRC,PIK3R1,MAP2K3,ARHGEF6,VAV2,CTNNA1,YES1,CDC42,PAK2,CTNNB1,CFL1,HRAS,MAP3K11,ACTR2,PARD6A,PIK3CA,DLG1,TIAM1,ARPC3,WASL,JUN,ARPC2,EPS8,PAX6,CBL
ret_pathway	Signaling events regulated by Ret tyrosine kinase	0.228416517456011	-1.47658448570648	38	16	0.020460358056266	782	2226	55816,5906,55715,220164,3265,2887,2549,3725,5781,5295,6464,4690,5578,6714,1385,5290	DOK5,RAP1A,DOK4,DOK6,HRAS,GRB10,GAB1,JUN,PTPN11,PIK3R1,SHC1,NCK1,PRKCA,SRC,CREB1,PIK3CA
pdgfrbpathway	PDGFR-beta signaling pathway	0.230865399567139	-1.46592042414426	54	22	0.0281329923273657	782	2226	867,2268,9368,5781,6772,6464,5728,4690,1785,5290,5770,207,1445,3265,2887,2549,4609,5295,7410,7525,6776,6714	CBL,FGR,NHERF1,PTPN11,STAT1,SHC1,PTEN,NCK1,DNM2,PIK3CA,PTPN1,AKT1,CSK,HRAS,GRB10,GAB1,MYC,PIK3R1,VAV2,YES1,STAT5A,SRC
nectin_pathway	Nectin adhesion pathway	0.231928134981871	-1.46132771831147	25	11	0.0140664961636829	782	2226	9076,5290,6714,5295,3685,998,7410,1495,1499,5819,50848	CLDN1,PIK3CA,SRC,PIK3R1,ITGAV,CDC42,VAV2,CTNNA1,CTNNB1,NECTIN2,F11R
ncadherinpathway	N-cadherin signaling events	0.239179526243718	-1.43054085319552	33	14	0.0179028132992327	782	2226	5770,818,1500,1499,1268,5295,22919,1495,2891,2260,2017,6093,2697,5290	PTPN1,CAMK2G,CTNND1,CTNNB1,CNR1,PIK3R1,MAPRE1,CTNNA1,GRIA2,FGFR1,CTTN,ROCK1,GJA1,PIK3CA
p38_mk2pathway	p38 signaling mediated by MAPKAP kinases	0.24061894282304	-1.4245407469404	20	9	0.0115089514066496	782	2226	7533,1385,2810,5894,7529,7532,7867,7534,3315	YWHAH,CREB1,SFN,RAF1,YWHAB,YWHAG,MAPKAPK3,YWHAZ,HSPB1
bmppathway	BMP receptor signaling	0.254211183328665	-1.3695899269826	36	15	0.0191815856777494	782	2226	659,4093,4089,26585,56963,4086,9241,25928,10106,4090,91851,285704,57154,9350,58190	BMPR2,SMAD9,SMAD4,GREM1,RGMA,SMAD1,NOG,SOSTDC1,CTDSP2,SMAD5,CHRDL1,RGMB,SMURF1,CER1,CTDSP1
aurora_a_pathway	Aurora A signaling	0.267463120142764	-1.31877359077601	31	13	0.0166240409207161	782	2226	332,4792,207,23424,672,4946,64506,7157,5901,51343,54998,4193,1647	BIRC5,NFKBIA,AKT1,TDRD7,BRCA1,OAZ1,CPEB1,TP53,RAN,FZR1,AURKAIP1,MDM2,GADD45A
bcr_5pathway	BCR signaling pathway	0.269921953930814	-1.30962242128502	66	26	0.0332480818414322	782	2226	6464,597,5290,8915,5728,3551,5604,3725,4792,2213,4793,1457,5530,7189,818,5894,2353,5295,974,7410,4790,2002,3265,1445,6850,207	SHC1,BCL2A1,PIK3CA,BCL10,PTEN,IKBKB,MAP2K1,JUN,NFKBIA,FCGR2B,NFKBIB,CSNK2A1,PPP3CA,TRAF6,CAMK2G,RAF1,FOS,PIK3R1,CD79B,VAV2,NFKB1,ELK1,HRAS,CSK,SYK,AKT1
fcer1pathway	Fc-epsilon receptor I signaling in mast cells	0.274199197088301	-1.29390044005551	58	23	0.0294117647058824	782	2226	3702,6464,5290,5781,3551,5604,3059,2207,3725,3937,2213,867,2353,5579,5894,5295,4790,3265,5062,7462,207,6850,1843	ITK,SHC1,PIK3CA,PTPN11,IKBKB,MAP2K1,HCLS1,FCER1G,JUN,LCP2,FCGR2B,CBL,FOS,PRKCB,RAF1,PIK3R1,NFKB1,HRAS,PAK2,LAT2,AKT1,SYK,DUSP1
arf_3pathway	Arf1 pathway	0.274975359414237	-1.29107378746013	18	8	0.010230179028133	782	2226	55738,9570,8394,1173,9266,160,375,920	ARFGAP1,GOSR2,PIP5K1A,AP2M1,CYTH2,AP2A1,ARF1,CD4
glypican_1pathway	Glypican 1 network	0.281907862961021	-1.26617498851952	26	11	0.0140664961636829	782	2226	2817,7525,2268,7043,462,5621,7048,4087,7422,2260,6714	GPC1,YES1,FGR,TGFB3,SERPINC1,PRNP,TGFBR2,SMAD2,VEGFA,FGFR1,SRC
alk1_2pathway	ALK1 pathway	0.283438390932521	-1.26076049536553	3	2	0.00255754475703325	782	2226	90,2280	ACVR1,FKBP1A
s1p_s1p5_pathway	S1P5 pathway	0.296134869658808	-1.21694028769158	8	4	0.0051150895140665	782	2226	2775,2771,2773,2781	GNAO1,GNAI2,GNAI3,GNAZ
s1p_meta_pathway	Sphingosine 1-phosphate (S1P) pathway	0.297771351384205	-1.21142936421878	21	9	0.0115089514066496	782	2226	8698,56848,2771,2776,2775,2773,2781,9630,2767	S1PR4,SPHK2,GNAI2,GNAQ,GNAO1,GNAI3,GNAZ,GNA14,GNA11
reelinpathway	Reelin signaling pathway	0.299155669819228	-1.20679120622783	29	12	0.0153452685421995	782	2226	4296,867,5906,207,1399,7436,8851,5048,5290,4131,5295,1020	MAP3K11,CBL,RAP1A,AKT1,CRKL,VLDLR,CDK5R1,PAFAH1B1,PIK3CA,MAP1B,PIK3R1,CDK5
p38_mkk3_6pathway	p38 MAPK signaling pathway	0.299155669819228	-1.20679120622783	29	12	0.0153452685421995	782	2226	10454,7189,4215,83605,5606,23118,4616,7295,1647,10912,7186,5608	TAB1,TRAF6,MAP3K3,CCM2,MAP2K3,TAB2,GADD45B,TXN,GADD45A,GADD45G,TRAF2,MAP2K6
ecadherin_stabilization_pathway	Stabilization and expansion of the E-cadherin adherens junction	0.310116186526488	-1.17080825647441	40	16	0.020460358056266	782	2226	1495,4233,382,4646,4690,6093,3480,11336,1500,26999,10787,360,5819,1499,7791,1969	CTNNA1,MET,ARF6,MYO6,NCK1,ROCK1,IGF1R,EXOC3,CTNND1,CYFIP2,NCKAP1,AQP3,NECTIN2,CTNNB1,ZYX,EPHA2
s1p_s1p2_pathway	S1P2 pathway	0.317424545304351	-1.14751514147796	24	10	0.0127877237851662	782	2226	9630,2002,2767,2773,2781,2775,2776,3725,2771,2353	GNA14,ELK1,GNA11,GNAI3,GNAZ,GNAO1,GNAQ,JUN,GNAI2,FOS
insulin_pathway	Insulin Pathway	0.322270347013942	-1.13236449869392	43	17	0.0217391304347826	782	2226	2887,3265,10640,50855,55763,5770,857,867,207,4690,5290,11336,208,6464,5781,55770,5295	GRB10,HRAS,EXOC5,PARD6A,EXOC1,PTPN1,CAV1,CBL,AKT1,NCK1,PIK3CA,EXOC3,AKT2,SHC1,PTPN11,EXOC2,PIK3R1
ar_pathway	Coregulation of Androgen receptor activity	0.335298575912964	-1.09273387272159	57	22	0.0281329923273657	782	2226	672,58190,4824,595,7329,354,1021,7520,896,9039,2288,1499,7337,3178,367,8554,10106,207,7041,27043,5052,23028	BRCA1,CTDSP1,NKX3-1,CCND1,UBE2I,KLK3,CDK6,XRCC5,CCND3,UBA3,FKBP4,CTNNB1,UBE3A,HNRNPA1,AR,PIAS1,CTDSP2,AKT1,TGFB1I1,PELP1,PRDX1,KDM1A
smad2_3pathway	Regulation of cytoplasmic and nuclear SMAD2/3 signaling	0.338353991881232	-1.08366261829095	19	8	0.010230179028133	782	2226	3838,58190,4087,9972,10106,7329,4089,4088	KPNA2,CTDSP1,SMAD2,NUP153,CTDSP2,UBE2I,SMAD4,SMAD3
pi3kcipathway	Class I PI3K signaling events	0.353726331782252	-1.03923173888565	41	16	0.020460358056266	782	2226	5906,3320,9267,9266,2268,5295,3636,9459,7525,375,7074,3702,6714,382,5290,5728	RAP1A,HSP90AA1,CYTH1,CYTH2,FGR,PIK3R1,INPPL1,ARHGEF6,YES1,ARF1,TIAM1,ITK,SRC,ARF6,PIK3CA,PTEN
a4b1_paxindep_pathway	Paxillin-independent events mediated by a4b1 and a4b7	0.35772904300405	-1.02797944226411	22	9	0.0115089514066496	782	2226	5290,382,6714,8174,1399,867,5295,2056,3717	PIK3CA,ARF6,SRC,MADCAM1,CRKL,CBL,PIK3R1,EPO,JAK2
s1p_s1p4_pathway	S1P4 pathway	0.363131629129786	-1.01298989576349	14	6	0.00767263427109974	782	2226	2775,2771,8698,998,2781,2773	GNAO1,GNAI2,S1PR4,CDC42,GNAZ,GNAI3
ephbfwdpathway	EPHB forward signaling	0.363787653950671	-1.01118494983826	33	13	0.0166240409207161	782	2226	1946,8976,3265,1947,5290,6714,7018,6093,4690,5295,2890,5604,998	EFNA5,WASL,HRAS,EFNB1,PIK3CA,SRC,TF,ROCK1,NCK1,PIK3R1,GRIA1,MAP2K1,CDC42
ptp1bpathway	Signaling events mediated by PTP1B	0.384817560192355	-0.954985926636296	50	19	0.0242966751918159	782	2226	2212,9021,207,823,5770,857,7295,2268,1445,7525,5295,3717,5617,5290,6714,3952,6776,6464,3953	FCGR2A,SOCS3,AKT1,CAPN1,PTPN1,CAV1,TXN,FGR,CSK,YES1,PIK3R1,JAK2,PRL,PIK3CA,SRC,LEP,STAT5A,SHC1,LEPR
wnt_beta_catenin_pathway	Regulation of Wnt-mediated beta catenin signaling and target gene transcription	0.391524517454345	-0.937707141107647	78	29	0.0370843989769821	782	2226	7088,367,22943,7015,10642,7529,1499,7514,6500,2810,56998,4609,10856,23043,4318,3576,1487,595,7534,170261,7532,9314,7533,4286,3725,607,6591,2033,26959	TLE1,AR,DKK1,TERT,IGF2BP1,YWHAB,CTNNB1,XPO1,SKP1,SFN,CTNNBIP1,MYC,RUVBL2,TNIK,MMP9,CXCL8,CTBP1,CCND1,YWHAZ,ZCCHC12,YWHAG,KLF4,YWHAH,MITF,JUN,BCL9,SNAI2,EP300,HBP1
botulinumtoxinpathway	Effects of Botulinum toxin	0.394266559916174	-0.930728050429045	9	4	0.0051150895140665	782	2226	6812,6616,6844,6804	STXBP1,SNAP25,VAMP2,STX1A
syndecan_4_pathway	Syndecan-4-mediated signaling events	0.402117771155747	-0.911010270194419	31	12	0.0153452685421995	782	2226	5340,6387,6386,7852,6352,7035,6385,1785,4318,2147,5578,2260	PLG,CXCL12,SDCBP,CXCR4,CCL5,TFPI,SDC4,DNM2,MMP9,F2,PRKCA,FGFR1
epha_fwdpathway	EPHA forward signaling	0.402117771155747	-0.911010270194419	31	12	0.0153452685421995	782	2226	2043,7525,7410,1020,6093,6714,1399,867,2268,1969,1946,1944	EPHA4,YES1,VAV2,CDK5,ROCK1,SRC,CRKL,CBL,FGR,EPHA2,EFNA5,EFNA3
p53regulationpathway	p53 pathway	0.410649601674186	-0.890014978784996	59	22	0.0281329923273657	782	2226	10419,9349,1456,1454,207,25898,10075,1452,8445,8493,1877,80854,1387,7157,64326,1434,890,4738,4193,80204,7321,2033	PRMT5,RPL23,CSNK1G3,CSNK1E,AKT1,RCHY1,HUWE1,CSNK1A1,DYRK2,PPM1D,E4F1,SETD7,CREBBP,TP53,COP1,CSE1L,CCNA2,NEDD8,MDM2,FBXO11,UBE2D1,EP300
erbb1_internalization_pathway	Internalization of ErbB1	0.413876587573809	-0.882187447244563	34	13	0.0166240409207161	782	2226	5868,7323,867,7251,9101,998,10617,5295,9146,5290,6714,5894,7321	RAB5A,UBE2D3,CBL,TSG101,USP8,CDC42,STAMBP,PIK3R1,HGS,PIK3CA,SRC,RAF1,UBE2D1
prlsignalingeventspathway	Signaling events mediated by PRL	0.418903143587212	-0.870115546671504	23	9	0.0115089514066496	782	2226	10376,890,5876,1026,8073,1958,6714,11156,6093	TUBA1B,CCNA2,RABGGTB,CDKN1A,PTP4A2,EGR1,SRC,PTP4A3,ROCK1
nfat_3pathway	Role of Calcineurin-dependent NFAT signaling in lymphocytes	0.425981413545095	-0.853359563840424	51	19	0.0242966751918159	782	2226	1457,7534,5588,1452,2810,7533,572,7514,2280,1387,7529,23770,7532,3838,5901,11261,5578,5581,2033	CSNK2A1,YWHAZ,PRKCQ,CSNK1A1,SFN,YWHAH,BAD,XPO1,FKBP1A,CREBBP,YWHAB,FKBP8,YWHAG,KPNA2,RAN,CHP1,PRKCA,PRKCE,EP300
nephrin_neph1_pathway	Nephrin/Neph1 signaling in the kidney podocyte	0.432243582953896	-0.838766000211072	26	10	0.0127877237851662	782	2226	50855,207,5295,23607,4690,572,3725,5290,5602,8976	PARD6A,AKT1,PIK3R1,CD2AP,NCK1,BAD,JUN,PIK3CA,MAPK10,WASL
syndecan_pathway	Proteogylcan syndecan-mediated signaling events	0.439351684229179	-0.822455083590983	4	2	0.00255754475703325	782	2226	6383,6385	SDC2,SDC4
arf6downstreampathway	Arf6 downstream pathway	0.439914349786348	-0.821175230594946	15	6	0.00767263427109974	782	2226	382,8394,375,7074,4830,8766	ARF6,PIP5K1A,ARF1,TIAM1,NME1,RAB11A
hif1apathway	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha	0.439914349786348	-0.821175230594946	15	6	0.00767263427109974	782	2226	10956,3320,10987,6921,7157,8453	OS9,HSP90AA1,COPS5,ELOC,TP53,CUL2
bard1pathway	BARD1 signaling events	0.44402009458897	-0.811885459490763	29	11	0.0140664961636829	782	2226	7520,7157,5111,2130,2189,4683,672,7332,7323,5932,11073	XRCC5,TP53,PCNA,EWSR1,FANCG,NBN,BRCA1,UBE2L3,UBE2D3,RBBP8,TOPBP1
insulin_glucose_pathway	Insulin-mediated glucose transport	0.44402009458897	-0.811885459490763	29	11	0.0140664961636829	782	2226	7534,6844,5501,9882,207,2997,2810,7533,7529,7532,208	YWHAZ,VAMP2,PPP1CC,TBC1D4,AKT1,GYS1,SFN,YWHAH,YWHAB,YWHAG,AKT2
avb3_integrin_pathway	Integrins in angiogenesis	0.451946404296264	-0.794191680746212	46	17	0.0217391304347826	782	2226	3611,7422,6696,1027,50848,3320,867,207,7048,6093,5290,6714,961,3480,3685,5781,5295	ILK,VEGFA,SPP1,CDKN1B,F11R,HSP90AA1,CBL,AKT1,TGFBR2,ROCK1,PIK3CA,SRC,CD47,IGF1R,ITGAV,PTPN11,PIK3R1
alphasynuclein_pathway	Alpha-synuclein signaling	0.454568671665186	-0.78840628400528	32	12	0.0153452685421995	782	2226	6850,7332,5653,1457,2268,6531,5330,572,2280,7525,10273,6714	SYK,UBE2L3,KLK6,CSNK2A1,FGR,SLC6A3,PLCB2,BAD,FKBP1A,YES1,STUB1,SRC
vegfr1_2_pathway	Signaling events mediated by VEGFR1 and VEGFR2	0.455863342262436	-0.785562202404153	63	23	0.0294117647058824	782	2226	7422,7424,857,3315,5578,6093,4690,5290,6464,3685,5781,2887,8829,2549,3265,1499,3320,207,6714,998,7525,5606,5295	VEGFA,VEGFC,CAV1,HSPB1,PRKCA,ROCK1,NCK1,PIK3CA,SHC1,ITGAV,PTPN11,GRB10,NRP1,GAB1,HRAS,CTNNB1,HSP90AA1,AKT1,SRC,CDC42,YES1,MAP2K3,PIK3R1
notch_pathway	Notch signaling pathway	0.48093029903028	-0.732032927837579	58	21	0.0268542199488491	782	2226	55851,867,5932,3565,595,1487,1026,171558,23385,6500,23028,55294,4609,3516,1272,51107,2033,8766,5045,2023,4853	PSENEN,CBL,RBBP8,IL4,CCND1,CTBP1,CDKN1A,PTCRA,NCSTN,SKP1,KDM1A,FBXW7,MYC,RBPJ,CNTN1,APH1A,EP300,RAB11A,FURIN,ENO1,NOTCH2
ceramide_pathway	Ceramide signaling pathway	0.488457754581474	-0.716502291113058	44	16	0.020460358056266	782	2226	4609,5604,1509,4790,8738,581,56848,5894,7124,4792,9131,207,8575,7186,572,5610	MYC,MAP2K1,CTSD,NFKB1,CRADD,BAX,SPHK2,RAF1,TNF,NFKBIA,AIFM1,AKT1,PRKRA,TRAF2,BAD,EIF2AK2
tnfpathway	TNF receptor signaling pathway	0.488457754581474	-0.716502291113058	44	16	0.020460358056266	782	2226	6610,7295,7186,857,4215,8878,7124,23043,7185,4790,6772,329,7133,3551,5606,7128	SMPD2,TXN,TRAF2,CAV1,MAP3K3,SQSTM1,TNF,TNIK,TRAF1,NFKB1,STAT1,BIRC2,TNFRSF1B,IKBKB,MAP2K3,TNFAIP3
p38gammadeltapathway	Signaling mediated by p38-gamma and p38-delta	0.489808848334529	-0.713740069428124	10	4	0.0051150895140665	782	2226	5608,5606,595,6640	MAP2K6,MAP2K3,CCND1,SNTA1
tcrjnkpathway	JNK signaling in the CD4+ TCR pathway	0.503652901679879	-0.685867935307791	13	5	0.00639386189258312	782	2226	3725,5579,9402,3937,1399	JUN,PRKCB,GRAP2,LCP2,CRKL
endothelinpathway	Endothelins	0.508277010944948	-0.676728682888388	53	19	0.0242966751918159	782	2226	2353,1278,5581,5894,5578,1281,6714,3717,23236,998,5604,3265,5330,3725,207,109,108,1909,5588	FOS,COL1A2,PRKCE,RAF1,PRKCA,COL3A1,SRC,JAK2,PLCB1,CDC42,MAP2K1,HRAS,PLCB2,JUN,AKT1,ADCY3,ADCY2,EDNRA,PRKCQ
anthraxpathway	Cellular roles of Anthrax toxin	0.531925060680515	-0.631252662945161	22	8	0.010230179028133	782	2226	22861,7124,5608,3606,3553,5241,5604,5606	NLRP1,TNF,MAP2K6,IL18,IL1B,PGR,MAP2K1,MAP2K3
txa2pathway	Thromboxane A2 receptor signaling	0.532729622244282	-0.629741258863014	45	16	0.020460358056266	782	2226	6093,5578,2782,6714,8766,5581,2771,7525,5330,9368,2268,54331,5588,6850,3383,207	ROCK1,PRKCA,GNB1,SRC,RAB11A,PRKCE,GNAI2,YES1,PLCB2,NHERF1,FGR,GNG2,PRKCQ,SYK,ICAM1,AKT1
amb2_neutrophils_pathway	amb2 Integrin signaling	0.538291676454495	-0.619354716186649	48	17	0.0217391304347826	782	2226	4790,7525,3569,6093,7124,4318,6714,207,3383,3146,5340,2268,3384,3240,4620,7070,177	NFKB1,YES1,IL6,ROCK1,TNF,MMP9,SRC,AKT1,ICAM1,HMGB1,PLG,FGR,ICAM2,HP,MYH2,THY1,AGER
erbb1_receptor_proximal_pathway	EGF receptor (ErbB1) signaling pathway	0.539059887138799	-0.617928606380971	25	9	0.0115089514066496	782	2226	5770,5781,2773,5295,6772,8976,2549,6714,5290	PTPN1,PTPN11,GNAI3,PIK3R1,STAT1,WASL,GAB1,SRC,PIK3CA
retinoic_acid_pathway	Retinoic acid receptors-mediated signaling	0.539059887138799	-0.617928606380971	25	9	0.0115089514066496	782	2226	983,1022,7421,207,5578,4331,6258,902,8841	CDK1,CDK7,VDR,AKT1,PRKCA,MNAT1,RXRG,CCNH,HDAC3
wnt_canonical_pathway	Canonical Wnt signaling pathway	0.551442967804333	-0.595216858502182	31	11	0.0140664961636829	782	2226	1499,59349,8452,5518,1452,6500,4040,1454,857,23291,1856	CTNNB1,KLHL12,CUL3,PPP2R1A,CSNK1A1,SKP1,LRP6,CSNK1E,CAV1,FBXW11,DVL2
mtor_4pathway	mTOR signaling pathway	0.557892500554447	-0.583588986496594	60	21	0.0268542199488491	782	2226	5894,5578,1975,27250,3551,54541,23291,5604,7532,1938,9821,7529,5371,54700,2810,1977,7533,84271,207,6009,7534	RAF1,PRKCA,EIF4B,PDCD4,IKBKB,DDIT4,FBXW11,MAP2K1,YWHAG,EEF2,RB1CC1,YWHAB,PML,RRN3,SFN,EIF4E,YWHAH,POLDIP3,AKT1,RHEB,YWHAZ
ephrina_ephapathway	EphrinA-EPHA pathway	0.575539348465743	-0.552447680497654	8	3	0.00383631713554987	782	2226	1969,2043,1946	EPHA2,EPHA4,EFNA5
ecadherin_1_pathway	E-cadherin signaling events	0.579294345672863	-0.545944561547144	2	1	0.00127877237851662	782	2226	1499	CTNNB1
syndecan_1_pathway	Syndecan-1-mediated signaling events	0.585216329710507	-0.535773705730435	17	6	0.00767263427109974	782	2226	5479,6352,6386,8573,4233,4318	PPIB,CCL5,SDCBP,CASK,MET,MMP9
s1p_s1p1_pathway	S1P1 pathway	0.588730330959285	-0.52978704234667	20	7	0.00895140664961637	782	2226	2775,5330,7422,2771,3685,2781,2773	GNAO1,PLCB2,VEGFA,GNAI2,ITGAV,GNAZ,GNAI3
erbb4_pathway	ErbB4 signaling events	0.602186646736133	-0.507187837314972	32	11	0.0140664961636829	782	2226	4193,5295,3717,5617,11059,6464,1742,5290,23118,6776,1839	MDM2,PIK3R1,JAK2,PRL,WWP1,SHC1,DLG4,PIK3CA,TAB2,STAT5A,HBEGF
rhoa_pathway	RhoA signaling pathway	0.611460155708033	-0.49190548426393	41	14	0.0179028132992327	782	2226	2353,5608,6093,5728,4478,5606,998,9475,1027,1072,3725,8394,4659,50855	FOS,MAP2K6,ROCK1,PTEN,MSN,MAP2K3,CDC42,ROCK2,CDKN1B,CFL1,JUN,PIP5K1A,PPP1R12A,PARD6A
plk1_pathway	PLK1 signaling events	0.614404580192834	-0.48710164243552	44	15	0.0191815856777494	782	2226	7178,5861,5518,9475,891,23291,7283,51343,147841,4659,3796,5500,10403,991,983	TPT1,RAB1A,PPP2R1A,ROCK2,CCNB1,FBXW11,TUBG1,FZR1,SPC24,PPP1R12A,KIF2A,PPP1CB,NDC80,CDC20,CDK1
wnt_noncanonical_pathway	Noncanonical Wnt signaling pathway	0.649179466231481	-0.432046073183446	30	10	0.0127877237851662	782	2226	7525,5468,1856,10454,998,23002,1452,6093,23118,5602	YES1,PPARG,DVL2,TAB1,CDC42,DAAM1,CSNK1A1,ROCK1,TAB2,MAPK10
syndecan_2_pathway	Syndecan-2-mediated signaling events	0.650058200638485	-0.430693380657048	33	11	0.0140664961636829	782	2226	6386,6383,3265,1437,3673,8573,858,581,6714,3576,51399	SDCBP,SDC2,HRAS,CSF2,ITGA2,CASK,CAV2,BAX,SRC,CXCL8,TRAPPC4
hes_heypathway	Notch-mediated HES/HEY network	0.656776573797479	-0.420411388658024	48	16	0.020460358056266	782	2226	3717,23028,920,23493,2033,3516,5925,2690,7088,5932,367,1487,1027,1387,3397,632	JAK2,KDM1A,CD4,HEY2,EP300,RBPJ,RB1,GHR,TLE1,RBBP8,AR,CTBP1,CDKN1B,CREBBP,ID1,BGLAP
rac1_pathway	RAC1 signaling pathway	0.659992101242636	-0.415527411847468	54	18	0.0230179028132992	782	2226	1495,29127,5606,394,6776,5608,26999,10787,10097,8394,3725,5330,4296,10109,10094,1499,5062,1072	CTNNA1,RACGAP1,MAP2K3,ARHGAP5,STAT5A,MAP2K6,CYFIP2,NCKAP1,ACTR2,PIP5K1A,JUN,PLCB2,MAP3K11,ARPC2,ARPC3,CTNNB1,PAK2,CFL1
cmyb_pathway	C-MYB transcription factor network	0.673604676361054	-0.395111873736885	78	26	0.0332480818414322	782	2226	1021,947,3312,5481,2033,3815,1387,1027,4173,595,5530,4069,7329,5250,6667,25942,1278,920,3015,891,4609,10043,171558,3950,1026,4144	CDK6,CD34,HSPA8,PPID,EP300,KIT,CREBBP,CDKN1B,MCM4,CCND1,PPP3CA,LYZ,UBE2I,SLC25A3,SP1,SIN3A,COL1A2,CD4,H2AZ1,CCNB1,MYC,TOM1,PTCRA,LECT2,CDKN1A,MAT2A
nfkappabalternativepathway	Alternative NF-kappaB pathway	0.68367425492482	-0.380273710285753	6	2	0.00255754475703325	782	2226	4790,9020	NFKB1,MAP3K14
wnt_signaling_pathway	Wnt signaling network	0.697416787369843	-0.360372073665451	28	9	0.0115089514066496	782	2226	10159,11197,8322,7472,22943,8323,3487,4040,7476	ATP6AP2,WIF1,FZD4,WNT2,DKK1,FZD6,IGFBP4,LRP6,WNT7A
ephrinarevpathway	Ephrin A  reverse signaling	0.727222323051932	-0.318523039323887	3	1	0.00127877237851662	782	2226	1946	EFNA5
glypicanpathway	Glypican pathway	0.727222323051932	-0.318523039323887	3	1	0.00127877237851662	782	2226	2817	GPC1
hnf3pathway	FOXA transcription factor networks	0.727222323051932	-0.318523039323887	3	1	0.00127877237851662	782	2226	3171	FOXA3
pi3kcibpathway	Class IB PI3K non-lipid kinase events	0.727222323051932	-0.318523039323887	3	1	0.00127877237851662	782	2226	5604	MAP2K1
ar_tf_pathway	Regulation of Androgen receptor activity	0.728807848994663	-0.316345163343197	50	16	0.020460358056266	782	2226	3320,6605,25898,354,367,3725,1387,4193,190,5608,5152,2033,10513,1958,6714,8805	HSP90AA1,SMARCE1,RCHY1,KLK3,AR,JUN,CREBBP,MDM2,NR0B1,MAP2K6,PDE9A,EP300,APPBP2,EGR1,SRC,TRIM24
faspathway	FAS (CD95) signaling pathway	0.735497691235356	-0.307207877986556	35	11	0.0140664961636829	782	2226	356,6850,207,5608,5602,5290,6714,355,5295,3551,329	FASLG,SYK,AKT1,MAP2K6,MAPK10,PIK3CA,SRC,FAS,PIK3R1,IKBKB,BIRC2
hivnefpathway	HIV-1 Nef: Negative effector of Fas and TNF-alpha	0.735497691235356	-0.307207877986556	35	11	0.0140664961636829	782	2226	919,7185,7124,355,1676,8738,4790,7186,9020,356,4792	CD247,TRAF1,TNF,FAS,DFFA,CRADD,NFKB1,TRAF2,MAP3K14,FASLG,NFKBIA
lymphangiogenesis_pathway	VEGFR3 signaling in lymphatic endothelium	0.751975087398782	-0.285052084040123	23	7	0.00895140664961637	782	2226	5290,1385,1278,3673,7424,5295,207	PIK3CA,CREB1,COL1A2,ITGA2,VEGFC,PIK3R1,AKT1
angiopoietinreceptor_pathway	Angiopoietin receptor Tie2-mediated signaling	0.762533391022064	-0.271108979955045	48	15	0.0191815856777494	782	2226	5340,207,284,1026,2002,1997,4790,5781,5295,7124,6776,4690,5290,2147,6464	PLG,AKT1,ANGPT1,CDKN1A,ELK1,ELF1,NFKB1,PTPN11,PIK3R1,TNF,STAT5A,NCK1,PIK3CA,F2,SHC1
rapid_gr_pathway	Rapid glucocorticoid signaling	0.768838889331383	-0.26287383814731	7	2	0.00255754475703325	782	2226	2782,54331	GNB1,GNG2
ephrinbrevpathway	Ephrin B reverse signaling	0.787306839784094	-0.239137221182947	27	8	0.010230179028133	782	2226	7074,5290,7852,7525,6714,2268,1947,5295	TIAM1,PIK3CA,CXCR4,YES1,SRC,FGR,EFNB1,PIK3R1
lis1pathway	Lissencephaly gene (LIS1) in neuronal migration and development	0.816446958576862	-0.202793330620668	31	9	0.0115089514066496	782	2226	998,1457,5048,1020,8851,7436,5049,4131,5050	CDC42,CSNK2A1,PAFAH1B1,CDK5,CDK5R1,VLDLR,PAFAH1B2,MAP1B,PAFAH1B3
hnf3bpathway	FOXA2 and FOXA3 transcription factor networks	0.826777626543363	-0.190219511841383	44	13	0.0166240409207161	782	2226	3157,7037,2147,1385,3767,6667,3171,7351,213,207,7276,3033,1375	HMGCS1,TFRC,F2,CREB1,KCNJ11,SP1,FOXA3,UCP2,ALB,AKT1,TTR,HADH,CPT1B
lpa4_pathway	LPA4-mediated signaling events	0.83083341910332	-0.185325962580573	15	4	0.0051150895140665	782	2226	5581,108,109,1385	PRKCE,ADCY2,ADCY3,CREB1
glypican_3pathway	Glypican 3 network	0.833272069621976	-0.18239507595005	8	2	0.00255754475703325	782	2226	2252,5045	FGF7,FURIN
et_egfrpathway	EGFR-dependent Endothelin signaling events	0.833272069621976	-0.18239507595005	8	2	0.00255754475703325	782	2226	1909,3265	EDNRA,HRAS
hedgehog_2pathway	Signaling events mediated by the Hedgehog family	0.841457249129705	-0.172620069815058	22	6	0.00767263427109974	782	2226	64399,5295,207,5744,5290,7042	HHIP,PIK3R1,AKT1,PTHLH,PIK3CA,TGFB2
fak_pathway	Signaling events mediated by focal adhesion kinase	0.841757993152004	-0.172262725111963	54	16	0.020460358056266	782	2226	5295,5604,3685,4323,9844,7525,9475,5894,6714,5290,9815,595,824,3693,8976,3725	PIK3R1,MAP2K1,ITGAV,MMP14,ELMO1,YES1,ROCK2,RAF1,SRC,PIK3CA,GIT2,CCND1,CAPN2,ITGB5,WASL,JUN
tgfbrpathway	TGF-beta receptor signaling	0.844817042947922	-0.168635192289595	51	15	0.0191815856777494	782	2226	5516,4089,4088,7043,6464,4087,7048,11059,857,50855,5371,57154,1499,2280,6711	PPP2CB,SMAD4,SMAD3,TGFB3,SHC1,SMAD2,TGFBR2,WWP1,CAV1,PARD6A,PML,SMURF1,CTNNB1,FKBP1A,SPTBN1
a4b1_paxdep_pathway	Paxillin-dependent events mediated by a4b1	0.853800735506648	-0.158057443207899	19	5	0.00639386189258312	782	2226	1399,5295,867,5290,382	CRKL,PIK3R1,CBL,PIK3CA,ARF6
aurora_b_pathway	Aurora B signaling	0.861440349827293	-0.149149465310019	39	11	0.0140664961636829	782	2226	29127,5037,5501,332,5684,8452,10051,1674,10403,23468,55958	RACGAP1,PEBP1,PPP1CC,BIRC5,PSMA3,CUL3,SMC4,DES,NDC80,CBX5,KLHL9
plk3_pathway	PLK3 signaling events	0.885408664200118	-0.12170597309823	5	1	0.00127877237851662	782	2226	7157	TP53
caspase_pathway	Caspase cascade in apoptosis	0.890006758976533	-0.116526221929134	50	14	0.0179028132992327	782	2226	6304,4000,7124,1676,581,4001,8738,7150,6709,2620,329,1073,7186,837	SATB1,LMNA,TNF,DFFA,BAX,LMNB1,CRADD,TOP1,SPTAN1,GAS2,BIRC2,CFL2,TRAF2,CASP4
rxr_vdr_pathway	RXR and RAR heterodimerization with other nuclear receptor	0.918253252868439	-0.0852820518236859	14	3	0.00383631713554987	782	2226	7421,6258,7124	VDR,RXRG,TNF
circadianpathway	Circadian rhythm pathway	0.918253252868439	-0.0852820518236859	14	3	0.00383631713554987	782	2226	1454,4841,8553	CSNK1E,NONO,BHLHE40
ephrinb_ephbpathway	EphrinB-EPHB pathway	0.925755546060181	-0.077145068323097	6	1	0.00127877237851662	782	2226	1947	EFNB1
rac1_reg_pathway	Regulation of RAC1 activity	0.9646190106901	-0.0360220631752071	39	9	0.0115089514066496	782	2226	7410,9844,7074,29127,9459,392,1124,2059,4830	VAV2,ELMO1,TIAM1,RACGAP1,ARHGEF6,ARHGAP1,CHN2,EPS8,NME1
trail_pathway	TRAIL signaling pathway	0.96958113780144	-0.0308911174439347	25	5	0.00639386189258312	782	2226	5290,3551,8743,7186,5295	PIK3CA,IKBKB,TNFSF10,TRAF2,PIK3R1
erbb_network_pathway	ErbB receptor signaling network	0.971377613387508	-0.0290399950561352	13	2	0.00255754475703325	782	2226	3320,1839	HSP90AA1,HBEGF
cdc42_reg_pathway	Regulation of CDC42 activity	0.978201713792931	-0.0220393788921837	30	6	0.00767263427109974	782	2226	998,392,7410,4830,9459,29127	CDC42,ARHGAP1,VAV2,NME1,ARHGEF6,RACGAP1
cone_pathway	Visual signal transduction: Cones	0.98290078431611	-0.017247095448624	23	4	0.0051150895140665	782	2226	2784,145226,2793,9227	GNB3,RDH12,GNGT2,LRAT
rhodopsin_pathway	Visual signal transduction: Rods	0.98290078431611	-0.017247095448624	23	4	0.0051150895140665	782	2226	5145,2782,9227,145226	PDE6A,GNB1,LRAT,RDH12
hdac_classiii_pathway	Signaling events mediated by HDAC Class III	0.985356743641021	-0.0147515270947475	39	8	0.010230179028133	782	2226	1387,51547,55902,10376,2033,581,1026,7157	CREBBP,SIRT7,ACSS2,TUBA1B,EP300,BAX,CDKN1A,TP53
rhoa_reg_pathway	Regulation of RhoA activity	0.99999478133176	-5.21868185731578e-06	46	4	0.0051150895140665	782	2226	4983,7410,1027,394	OPHN1,VAV2,CDKN1B,ARHGAP5
plk2_4pathway	PLK2 and PLK4 events	0.999999999994063	-5.93727844666603e-12	2	0	0	782	2226
glypican_2pathway	Glypican 2 network	0.999999999994063	-5.93727844666603e-12	2	0	0	782	2226
aurora_kinase_pathway	Signaling by Aurora kinases	0.999999999998798	-1.20198295761043e-12	3	0	0	782	2226
a4b1_a4b7_pathway	a4b1 and a4b7 Integrin signaling	0.999999999998798	-1.20198295761043e-12	3	0	0	782	2226
aurora_c_pathway	Aurora C signaling	0.999999999998798	-1.20198295761043e-12	3	0	0	782	2226
plk_pathway	Polo-like kinase signaling events in the cell cycle	1.00000000000628	6.27583922330199e-12	4	0	0	782	2226