TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
WP477	Cytoplasmic Ribosomal Proteins	9.5284577244185e-08	-16.1663978731269	90	57	0.0298429319371728	1910	5310	6132,4736,6157,6207,6231,6147,6187,6235,6175,11224,6130,6152,6176,6234,9349,6160,2197,6129,7311,6128,6124,6218,6233,6203,6143,6188,6134,6165,6136,6138,6159,6229,6209,6161,6139,6133,6154,6158,6204,6146,6208,6191,6206,6224,6228,6155,6205,6217,6193,6181,6141,6201,3921,6170,23521,6122,6168	RPL8,RPL10A,RPL27A,RPS13,RPS26,RPL23A,RPS2,RPS29,RPLP0,RPL35,RPL7A,RPL24,RPLP1,RPS28,RPL23,RPL31,FAU,RPL7,UBA52,RPL6,RPL4,RPS17,RPS27A,RPS9,RPL19,RPS3,RPL10,RPL35A,RPL12,RPL15,RPL29,RPS24,RPS15,RPL32,RPL17,RPL9,RPL26,RPL28,RPS10,RPL22,RPS14,RPS4X,RPS12,RPS20,RPS23,RPL27,RPS11,RPS16,RPS5,RPLP2,RPL18,RPS7,RPSA,RPL39,RPL13A,RPL3,RPL37A
WP75	Toll-like Receptor Signaling Pathway	1.05063786041951e-06	-13.766113092126	103	61	0.0319371727748691	1910	5310	7100,10454,29110,3553,3725,51311,5294,5296,3447,3440,6373,114609,54472,148022,7098,7096,207,941,5608,5606,5604,3569,3593,7099,7189,5295,3551,6352,4615,3627,4792,3446,3454,3456,208,6696,942,23643,5290,7124,51135,4790,929,8503,3576,4283,54106,2353,958,5602,10333,23118,3665,10000,353376,7097,6772,3592,51284,3661,6348	TLR5,TAB1,TBK1,IL1B,JUN,TLR8,PIK3CG,PIK3R2,IFNA13,IFNA2,CXCL11,TIRAP,TOLLIP,TICAM1,TLR3,TLR1,AKT1,CD80,MAP2K6,MAP2K3,MAP2K1,IL6,IL12B,TLR4,TRAF6,PIK3R1,IKBKB,CCL5,MYD88,CXCL10,NFKBIA,IFNA10,IFNAR1,IFNB1,AKT2,SPP1,CD86,LY96,PIK3CA,TNF,IRAK4,NFKB1,CD14,PIK3R3,CXCL8,CXCL9,TLR9,FOS,CD40,MAPK10,TLR6,TAB2,IRF7,AKT3,TICAM2,TLR2,STAT1,IL12A,TLR7,IRF3,CCL3
WP3877	Simplified Depiction of MYD88 Distinct Input-Output Pathway	2.02489714464472e-06	-13.1099916514638	19	17	0.00890052356020942	1910	5310	51284,7334,81793,7097,7189,7099,4790,4615,3552,3725,7096,7100,92610,10333,7335,54106,51311	TLR7,UBE2N,TLR10,TLR2,TRAF6,TLR4,NFKB1,MYD88,IL1A,JUN,TLR1,TLR5,TIFA,TLR6,UBE2V1,TLR9,TLR8
WP1449	Regulation of toll-like receptor signaling pathway	3.08113172503373e-06	-12.6902135852767	145	79	0.0413612565445026	1910	5310	3447,407054,4153,6373,3440,114609,54472,7100,29110,10454,3553,3725,51311,5296,5294,7099,5295,7189,3551,23098,6352,10771,4615,148022,7096,7098,10616,207,941,5604,3569,3593,5608,5606,10906,5290,23643,6850,57162,51014,7124,7128,51135,1154,929,4790,406891,92610,3627,4792,3446,3456,3454,208,942,6696,406897,7097,353376,6772,51284,3592,6441,246330,10193,6348,3661,8503,3576,8878,958,54106,2353,4283,5602,23118,10333,10000,3665	IFNA13,MIR98,MBL2,CXCL11,IFNA2,TIRAP,TOLLIP,TLR5,TBK1,TAB1,IL1B,JUN,TLR8,PIK3R2,PIK3CG,TLR4,PIK3R1,TRAF6,IKBKB,SARM1,CCL5,ZMYND11,MYD88,TICAM1,TLR1,TLR3,RBCK1,AKT1,CD80,MAP2K1,IL6,IL12B,MAP2K6,MAP2K3,TRAFD1,PIK3CA,LY96,SYK,PELI1,TMED7,TNF,TNFAIP3,IRAK4,CISH,CD14,NFKB1,MIRLET7I,TIFA,CXCL10,NFKBIA,IFNA10,IFNB1,IFNAR1,AKT2,CD86,SPP1,MIR105-1,TLR2,TICAM2,STAT1,TLR7,IL12A,SFTPD,PELI3,RNF41,CCL3,IRF3,PIK3R3,CXCL8,SQSTM1,CD40,TLR9,FOS,CXCL9,MAPK10,TAB2,TLR6,AKT3,IRF7
WP619	Type II interferon signaling (IFNG)	2.17402651097278e-05	-10.7363444817859	37	26	0.0136125654450262	1910	5310	5698,3659,4938,6773,3383,9021,4283,6772,3553,3456,3458,3433,10379,5967,3394,3627,9636,3660,2537,3717,5781,3459,5610,3662,3440,3716	PSMB9,IRF1,OAS1,STAT2,ICAM1,SOCS3,CXCL9,STAT1,IL1B,IFNB1,IFNG,IFIT2,IRF9,REG1A,IRF8,CXCL10,ISG15,IRF2,IFI6,JAK2,PTPN11,IFNGR1,EIF2AK2,IRF4,IFNA2,JAK1
WP111	Electron Transport Chain	4.04213278633012e-05	-10.1161529948881	92	52	0.0272251308900524	1910	5310	1346,4706,4726,4728,1339,515,514,27089,522,1349,518,4729,513,1353,506,4712,1351,498,516,10632,539,4697,6391,1327,1345,4710,10476,292,7385,4722,10063,6390,7351,4711,9481,1340,4695,55967,291,10975,4720,4694,4698,4714,4718,4716,9377,93974,9016,7388,7384,4713	COX7A1,NDUFAB1,NDUFS6,NDUFS8,COX6A2,ATP5PB,ATP5F1E,UQCRQ,ATP5PF,COX7B,ATP5MC3,NDUFV2,ATP5F1D,COX11,ATP5F1B,NDUFB6,COX8A,ATP5F1A,ATP5MC1,ATP5MG,ATP5PO,NDUFA4,SDHC,COX4I1,COX6C,NDUFB4,ATP5PD,SLC25A5,UQCRC2,NDUFS3,COX17,SDHB,UCP2,NDUFB5,SLC25A27,COX6B1,NDUFA2,NDUFA12,SLC25A4,UQCR11,NDUFS2,NDUFA1,NDUFA5,NDUFB8,NDUFC2,NDUFB10,COX5A,ATP5IF1,SLC25A14,UQCRH,UQCRC1,NDUFB7
WP15	Selenium Micronutrient Network	7.59203523853761e-05	-9.48582576213786	87	49	0.0256544502617801	1910	5310	5052,2147,6647,257202,114112,55163,6347,3569,2877,85465,3949,12,55829,3553,10549,5340,58515,51734,10587,6649,7296,83642,1733,213,2876,2878,6648,1734,3383,2879,6415,3043,9403,6414,7124,10935,241,4790,22928,2155,1735,51714,3458,3039,7001,348303,140606,57190,7295	PRDX1,F2,SOD1,GPX6,TXNRD3,PNPO,CCL2,IL6,GPX2,SELENOI,LDLR,SERPINA3,SELENOS,IL1B,PRDX4,PLG,SELENOK,MSRB1,TXNRD2,SOD3,TXNRD1,SELENOO,DIO1,ALB,GPX1,GPX3,SOD2,DIO2,ICAM1,GPX4,SELENOW,HBB,SELENOF,SELENOP,TNF,PRDX3,ALOX5AP,NFKB1,SEPHS2,F7,DIO3,SELENOT,IFNG,HBA1,PRDX2,SELENOV,SELENOM,SELENON,TXN
WP2032	Human Thyroid Stimulating Hormone (TSH) signaling pathway	9.40429686236374e-05	-9.27175876712118	68	40	0.0209424083769634	1910	5310	2773,100126338,5604,1385,5606,5608,5925,2353,207,896,1958,6772,4609,5295,108,2776,1019,23236,3480,3725,103910,54331,328,2775,3265,109,7253,6714,30818,5894,3717,5296,2771,5906,5908,5290,1027,2782,406974,3716	GNAI3,MIR937,MAP2K1,CREB1,MAP2K3,MAP2K6,RB1,FOS,AKT1,CCND3,EGR1,STAT1,MYC,PIK3R1,ADCY2,GNAQ,CDK4,PLCB1,IGF1R,JUN,MYL12B,GNG2,APEX1,GNAO1,HRAS,ADCY3,TSHR,SRC,KCNIP3,RAF1,JAK2,PIK3R2,GNAI2,RAP1A,RAP1B,PIK3CA,CDKN1B,GNB1,MIR197,JAK1
WP411	mRNA Processing	0.000155537260131642	-8.76862524005359	132	68	0.0356020942408377	1910	5310	8559,6432,1479,3190,6626,6628,84991,53981,10907,3178,8405,10181,6629,23283,9785,22826,23405,1660,6637,3182,10978,6429,57396,100126351,6625,10262,6632,6729,10914,23451,57819,6426,3181,6434,1195,22916,1665,693221,1653,6733,29894,4841,6635,100302196,3275,57794,6627,10898,8449,10421,5496,51362,83443,6633,3188,3184,6427,10291,6829,3183,3191,5681,407043,6634,6638,9410,10772,9128	PRPF18,SRSF7,CSTF3,HNRNPK,SNRPA,SNRPB,RBM17,CPSF2,TXNL4A,HNRNPA1,SPOP,RBM5,SNRPB2,CSTF2T,DHX38,DNAJC8,DICER1,DHX9,SNRPG,HNRNPAB,CLP1,SRSF4,CLK4,MIR939,SNRNP70,SF3B4,SNRPD1,SRP54,PAPOLA,SF3B1,LSM2,SRSF1,HNRNPA2B1,TRA2B,CLK1,NCBP2,DHX15,MIR636,DDX1,SRPK2,CPSF1,NONO,SNRPE,MIR1234,PRMT2,SUGP1,SNRPA1,CPSF4,DHX16,CD2BP2,PPM1G,CDC40,SF3B5,SNRPD2,HNRNPH2,HNRNPD,SRSF2,SF3A1,SUPT5H,HNRNPC,HNRNPL,PSKH1,MIR7-1,SNRPD3,SNRPN,SNRNP40,SRSF10,PRPF4
WP28	Selenium Metabolism and Selenoproteins	0.000160512406749151	-8.73713931776398	46	29	0.0151832460732984	1910	5310	1735,55829,22928,4790,85465,6414,6667,57190,140606,58515,22929,348303,3725,51714,2876,2878,1733,83642,114112,7296,257202,10587,51734,6415,2877,4780,2879,2353,1734	DIO3,SELENOS,SEPHS2,NFKB1,SELENOI,SELENOP,SP1,SELENON,SELENOM,SELENOK,SEPHS1,SELENOV,JUN,SELENOT,GPX1,GPX3,DIO1,SELENOO,TXNRD3,TXNRD1,GPX6,TXNRD2,MSRB1,SELENOW,GPX2,NFE2L2,GPX4,FOS,DIO2
WP183	Proteasome Degradation	0.000260177211250834	-8.25414757738611	66	38	0.0198952879581152	1910	5310	5707,7320,5709,5682,5684,7323,5686,5700,5720,5695,5704,5689,5702,3458,5687,5691,5683,8335,3014,6184,3015,5699,5693,5705,5713,5690,9861,7347,5710,5692,5694,5698,5718,7321,5716,7314,5721,5685	PSMD1,UBE2B,PSMD3,PSMA1,PSMA3,UBE2D3,PSMA5,PSMC1,PSME1,PSMB7,PSMC4,PSMB1,PSMC3,IFNG,PSMA6,PSMB3,PSMA2,H2AC4,H2AX,RPN1,H2AZ1,PSMB10,PSMB5,PSMC5,PSMD7,PSMB2,PSMD6,UCHL3,PSMD4,PSMB4,PSMB6,PSMB9,PSMD12,UBE2D1,PSMD10,UBB,PSME2,PSMA4
WP530	Cytokines and Inflammatory Response	0.000562457670131514	-7.48319467981689	26	18	0.00942408376963351	1910	5310	3552,3558,3562,7124,920,3596,1437,3567,3593,3569,3600,3565,3458,3456,2919,3553,3586,3574	IL1A,IL2,IL3,TNF,CD4,IL13,CSF2,IL5,IL12B,IL6,IL15,IL4,IFNG,IFNB1,CXCL1,IL1B,IL10,IL7
WP3858	Toll-like Receptor Signaling	0.000596792555884684	-7.42394098253609	32	21	0.0109947643979058	1910	5310	353376,7189,7097,7099,51284,3551,3661,4790,54472,4615,114609,51135,29110,7098,7096,7100,148022,54106,51311,3665,10333	TICAM2,TRAF6,TLR2,TLR4,TLR7,IKBKB,IRF3,NFKB1,TOLLIP,MYD88,TIRAP,IRAK4,TBK1,TLR3,TLR1,TLR5,TICAM1,TLR9,TLR8,IRF7,TLR6
WP615	Senescence and Autophagy in Cancer	0.00101733344639416	-6.89057034309355	106	54	0.0282722513089005	1910	5310	3562,6348,10533,6041,5925,7157,3159,5111,3665,3659,3576,84557,4323,23770,8878,1027,3486,3552,3622,6714,11345,11337,3456,3458,9966,81631,9821,29985,3621,4193,4089,3920,3479,5604,3569,55054,5606,64422,51100,4088,9547,3428,3572,23710,8678,1281,1026,5894,3265,5728,3553,2919,3480,3725	IL3,CCL3,ATG7,RNASEL,RB1,TP53,HMGA1,PCNA,IRF7,IRF1,CXCL8,MAP1LC3A,MMP14,FKBP8,SQSTM1,CDKN1B,IGFBP3,IL1A,ING2,SRC,GABARAPL2,GABARAP,IFNB1,IFNG,TNFSF15,MAP1LC3B,RB1CC1,SLC39A3,ING1,MDM2,SMAD4,LAMP2,IGF1,MAP2K1,IL6,ATG16L1,MAP2K3,ATG3,SH3GLB1,SMAD3,CXCL14,IFI16,IL6ST,GABARAPL1,BECN1,COL3A1,CDKN1A,RAF1,HRAS,PTEN,IL1B,CXCL1,IGF1R,JUN
WP1545	miRNAs involved in DNA damage response	0.00116939861653127	-6.751265665282	50	29	0.0151832460732984	1910	5310	595,4609,407041,442918,407010,100126302,407042,1021,406900,1385,407014,693122,407007,693123,7157,554213,896,664617,406950,407006,574506,1027,407011,406992,406886,406937,1026,3014,406892	CCND1,MYC,MIR34B,MIR373,MIR23A,MIR450B,MIR34C,CDK6,MIR106B,CREB1,MIR25,MIR421,MIR222,MIR449B,TP53,MIR449A,CCND3,MIR542,MIR16-1,MIR221,MIR503,CDKN1B,MIR23B,MIR210,MIRLET7D,MIR145,CDKN1A,H2AX,MIR100
WP3863	T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection	0.00175351970375397	-6.34613025163282	62	34	0.0178010471204188	1910	5310	3458,3565,5133,3725,3586,3937,4792,11261,940,9402,5894,29851,10598,867,920,1493,5290,9020,4790,3558,7124,959,1437,3567,5604,2353,207,8915,3551,1739,4690,5588,3702,1019	IFNG,IL4,PDCD1,JUN,IL10,LCP2,NFKBIA,CHP1,CD28,GRAP2,RAF1,ICOS,AHSA1,CBL,CD4,CTLA4,PIK3CA,MAP3K14,NFKB1,IL2,TNF,CD40LG,CSF2,IL5,MAP2K1,FOS,AKT1,BCL10,IKBKB,DLG1,NCK1,PRKCQ,ITK,CDK4
WP3851	TLR4 Signaling and Tolerance	0.00203994170205072	-6.19483404896047	30	19	0.00994764397905759	1910	5310	7124,3661,114609,23471,51135,4615,4790,7099,7189,3551,23118,3569,3665,148022,3576,29110,10454,4792,3456	TNF,IRF3,TIRAP,TRAM1,IRAK4,MYD88,NFKB1,TLR4,TRAF6,IKBKB,TAB2,IL6,IRF7,TICAM1,CXCL8,TBK1,TAB1,NFKBIA,IFNB1
WP2865	IL1 and megakaryocytes in obesity	0.00395717596517843	-5.53222464822757	25	16	0.00837696335078534	1910	5310	2147,7097,3606,7076,5290,1839,114548,4615,4318,4790,1232,7096,3553,3458,6347,3383	F2,TLR2,IL18,TIMP1,PIK3CA,HBEGF,NLRP3,MYD88,MMP9,NFKB1,CCR3,TLR1,IL1B,IFNG,CCL2,ICAM1
WP3611	Photodynamic therapy-induced AP-1 survival signaling.	0.00426214213777787	-5.45798339584354	51	28	0.0146596858638743	1910	5310	581,7186,5608,5606,890,598,3569,4780,7157,4170,2353,5925,595,1839,7189,2002,3726,578,356,3725,2252,3458,8743,1026,3320,355,7124,3558	BAX,TRAF2,MAP2K6,MAP2K3,CCNA2,BCL2L1,IL6,NFE2L2,TP53,MCL1,FOS,RB1,CCND1,HBEGF,TRAF6,ELK1,JUNB,BAK1,FASLG,JUN,FGF7,IFNG,TNFSF10,CDKN1A,HSP90AA1,FAS,TNF,IL2
WP2249	Metastatic brain tumor	0.00651990599721663	-5.03289532075232	28	17	0.00890052356020942	1910	5310	1021,442892,406890,406884,406940,7157,406885,406893,407041,4609,407021,5295,406894,406886,407042,998,407026	CDK6,MIR148B,MIRLET7G,MIRLET7B,MIR148A,TP53,MIRLET7C,MIR101-1,MIR34B,MYC,MIR29A,PIK3R1,MIR101-2,MIRLET7D,MIR34C,CDC42,MIR29C
WP49	IL-2 Signaling Pathway	0.00961226897229497	-4.64471497853075	42	23	0.0120418848167539	1910	5310	5295,6776,4609,6464,1399,6772,9111,3560,207,2353,9021,5604,3561,6850,5781,3716,3558,1154,3265,3725,3559,867,5894	PIK3R1,STAT5A,MYC,SHC1,CRKL,STAT1,NMI,IL2RB,AKT1,FOS,SOCS3,MAP2K1,IL2RG,SYK,PTPN11,JAK1,IL2,CISH,HRAS,JUN,IL2RA,CBL,RAF1
WP405	Eukaryotic Transcription Initiation	0.00961226897229497	-4.64471497853075	42	23	0.0120418848167539	1910	5310	2968,2966,84172,6879,5438,5436,5432,2960,4331,2963,51082,2958,5435,3611,2961,55703,2071,2959,902,171568,6880,1022,5431	GTF2H4,GTF2H2,POLR1B,TAF7,POLR2I,POLR2G,POLR2C,GTF2E1,MNAT1,GTF2F2,POLR1D,GTF2A2,POLR2F,ILK,GTF2E2,POLR3B,ERCC3,GTF2B,CCNH,POLR3H,TAF9,CDK7,POLR2B
WP3850	Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling	0.00978296143863876	-4.62711303518499	31	18	0.00942408376963351	1910	5310	5564,1977,5728,4088,3480,84557,5294,207,3479,51528,8976,2660,4087,8892,3611,84676,114907,4790	PRKAB1,EIF4E,PTEN,SMAD3,IGF1R,MAP1LC3A,PIK3CG,AKT1,IGF1,JKAMP,WASL,MSTN,SMAD2,EIF2B2,ILK,TRIM63,FBXO32,NFKB1
WP1272	Selenium Micronutrient Network	0.0104434393851162	-4.56178130776329	7	6	0.0031413612565445	1910	5310	7295,6415,114112,7296,10587,51734	TXN,SELENOW,TXNRD3,TXNRD1,TXNRD2,MSRB1
WP1310	Selenium Micronutrient Network	0.0104434393851162	-4.56178130776329	7	6	0.0031413612565445	1910	5310	114112,7295,6415,51734,10587,7296	TXNRD3,TXN,SELENOW,MSRB1,TXNRD2,TXNRD1
WP3624	Lung fibrosis	0.0108337023063169	-4.52509341984991	63	32	0.0167539267015707	1910	5310	6348,6352,6356,5265,3596,7076,7015,729230,6347,653509,3593,3569,3479,3567,26585,4780,1437,3576,1232,7124,4318,255520,79991,6696,4502,4204,6440,2252,1215,3565,3553,2246	CCL3,CCL5,CCL11,SERPINA1,IL13,TIMP1,TERT,CCR2,CCL2,SFTPA1,IL12B,IL6,IGF1,IL5,GREM1,NFE2L2,CSF2,CXCL8,CCR3,TNF,MMP9,ELMOD2,STN1,SPP1,MT2A,MECP2,SFTPC,FGF7,CMA1,IL4,IL1B,FGF1
WP45	G1 to S cell cycle control	0.0118124124408539	-4.43860439860423	68	34	0.0178010471204188	1910	5310	4609,23594,4172,23649,1032,595,6119,7029,1019,5001,4193,1021,5558,5925,7157,4331,896,6118,5111,4173,983,1385,10488,1027,148327,1031,1647,902,1876,1874,891,1022,4175,1026	MYC,ORC6,MCM3,POLA2,CDKN2D,CCND1,RPA3,TFDP2,CDK4,ORC5,MDM2,CDK6,PRIM2,RB1,TP53,MNAT1,CCND3,RPA2,PCNA,MCM4,CDK1,CREB1,CREB3,CDKN1B,CREB3L4,CDKN2C,GADD45A,CCNH,E2F6,E2F4,CCNB1,CDK7,MCM6,CDKN1A
WP623	Oxidative phosphorylation	0.0118231617922979	-4.43769480765636	54	28	0.0146596858638743	1910	5310	4710,10476,4713,10159,539,4697,498,10632,516,4718,4716,4714,4698,4712,4695,506,4720,518,513,4729,515,522,4711,514,4722,4728,4726,4706	NDUFB4,ATP5PD,NDUFB7,ATP6AP2,ATP5PO,NDUFA4,ATP5F1A,ATP5MG,ATP5MC1,NDUFC2,NDUFB10,NDUFB8,NDUFA5,NDUFB6,NDUFA2,ATP5F1B,NDUFS2,ATP5MC3,ATP5F1D,NDUFV2,ATP5PB,ATP5PF,NDUFB5,ATP5F1E,NDUFS3,NDUFS8,NDUFS6,NDUFAB1
WP205	IL-7 Signaling Pathway	0.0121266683449261	-4.41234825616615	25	15	0.00785340314136126	1910	5310	4609,6776,3561,5295,6772,595,3716,1027,3574,572,5296,207,3559,598,5604	MYC,STAT5A,IL2RG,PIK3R1,STAT1,CCND1,JAK1,CDKN1B,IL7,BAD,PIK3R2,AKT1,IL2RA,BCL2L1,MAP2K1
WP195	IL-1 signaling pathway	0.0144925421044762	-4.2341210994949	57	29	0.0151832460732984	1910	5310	8878,5608,5606,5604,23118,3316,6347,207,3551,7334,7189,5295,4615,3725,3553,10454,4792,7335,5296,57162,5781,4215,54472,4790,3552,9020,51135,4793,3556	SQSTM1,MAP2K6,MAP2K3,MAP2K1,TAB2,HSPB2,CCL2,AKT1,IKBKB,UBE2N,TRAF6,PIK3R1,MYD88,JUN,IL1B,TAB1,NFKBIA,UBE2V1,PIK3R2,PELI1,PTPN11,MAP3K3,TOLLIP,NFKB1,IL1A,MAP3K14,IRAK4,NFKBIB,IL1RAP
WP3893	Development and heterogeneity of the ILC family	0.0149582914319502	-4.2024895220524	32	18	0.00942408376963351	1910	5310	3592,3606,2672,3596,50616,7704,7124,51561,3553,3458,3565,3574,3593,3569,3567,9760,3600,4783	IL12A,IL18,GFI1,IL13,IL22,ZBTB16,TNF,IL23A,IL1B,IFNG,IL4,IL7,IL12B,IL6,IL5,TOX,IL15,NFIL3
WP2586	Aryl Hydrocarbon Receptor	0.0157987209772068	-4.14782629303561	48	25	0.0130890052356021	1910	5310	948,9049,2729,4609,6346,1543,3845,7422,5604,4780,5925,2033,3320,4790,1027,1728,7124,1545,3265,5894,84722,1026,5325,6714,27306	CD36,AIP,GCLC,MYC,CCL1,CYP1A1,KRAS,VEGFA,MAP2K1,NFE2L2,RB1,EP300,HSP90AA1,NFKB1,CDKN1B,NQO1,TNF,CYP1B1,HRAS,RAF1,PSRC1,CDKN1A,PLAGL1,SRC,HPGDS
WP254	Apoptosis	0.0162567906370028	-4.11924457214214	86	41	0.0214659685863874	1910	5310	666,3480,8738,3725,572,8743,4792,332,3660,3664,837,3662,355,4790,7185,4793,7124,581,665,7186,3659,1676,3479,598,4049,3665,3070,4170,7157,207,5602,3551,4609,329,5295,5366,4193,578,356,7133,3661	BOK,IGF1R,CRADD,JUN,BAD,TNFSF10,NFKBIA,BIRC5,IRF2,IRF6,CASP4,IRF4,FAS,NFKB1,TRAF1,NFKBIB,TNF,BAX,BNIP3L,TRAF2,IRF1,DFFA,IGF1,BCL2L1,LTA,IRF7,HELLS,MCL1,TP53,AKT1,MAPK10,IKBKB,MYC,BIRC2,PIK3R1,PMAIP1,MDM2,BAK1,FASLG,TNFRSF1B,IRF3
WP2059	Alzheimers Disease	0.0175012459411975	-4.04548320394717	148	66	0.0345549738219895	1910	5310	407021,5330,355,8883,407001,824,768217,51107,3553,406902,572,406921,5535,693120,823,100422912,574441,100126316,406958,406931,406927,8851,4311,407046,100126348,2776,407000,494326,407051,768213,3028,407052,693183,1020,574453,406991,494324,7124,406960,23236,54480,84833,407047,11261,3416,100126347,51806,406893,406918,81671,5663,100126343,407041,2597,100506742,407042,406917,55851,5530,574457,23385,100126333,7157,23621,5664,406910	MIR29A,PLCB2,FAS,NAE1,MIR218-2,CAPN2,MIR769,APH1A,IL1B,MIR10A,BAD,MIR132,PPP3R2,MIR33B,CAPN1,MIR3200,MIR488,MIR873,MIR182,MIR139,MIR136,CDK5R1,MME,MIR9-1,MIR760,GNAQ,MIR218-1,MIR377,MIR9-3,MIR671,HSD17B10,MIR95,MIR598,CDK5,MIR495,MIR21,MIR375,TNF,MIR184,PLCB1,CHPF2,ATP5MK,MIR9-2,CHP1,IDE,MIR887,CALML5,MIR101-1,MIR129-2,VMP1,PSEN1,MIR874,MIR34B,GAPDH,CASP12,MIR34C,MIR129-1,PSENEN,PPP3CA,MIR181D,NCSTN,MIR708,TP53,BACE1,PSEN2,MIR125A
WP3614	Photodynamic therapy-induced HIF-1 survival signaling	0.018253456227387	-4.00340083456163	37	20	0.0104712041884817	1910	5310	7422,3939,665,581,284,5230,6566,7157,4170,598,332,597,7043,5366,6515,2056,6513,5160,3486,578	VEGFA,LDHA,BNIP3L,BAX,ANGPT1,PGK1,SLC16A1,TP53,MCL1,BCL2L1,BIRC5,BCL2A1,TGFB3,PMAIP1,SLC2A3,EPO,SLC2A1,PDHA1,IGFBP3,BAK1
WP3617	Photodynamic therapy-induced NF-kB survival signaling	0.0200590814066888	-3.90907328978554	35	19	0.00994764397905759	1910	5310	7189,329,3551,595,3558,959,7124,3552,4318,4790,7422,3576,112398,3553,332,1437,597,3383,3569	TRAF6,BIRC2,IKBKB,CCND1,IL2,CD40LG,TNF,IL1A,MMP9,NFKB1,VEGFA,CXCL8,EGLN2,IL1B,BIRC5,CSF2,BCL2A1,ICAM1,IL6
WP2431	Spinal Cord Injury	0.020495653533026	-3.887542438097	119	54	0.0282722513089005	1910	5310	57142,5803,50515,7124,3552,407011,1027,5578,3627,2212,2280,3458,3952,2043,5322,361,4609,8741,1019,998,5530,4050,3576,56963,7157,2353,5925,9475,983,3383,2697,3558,4318,961,1647,328,7832,3565,6662,388,4974,2919,199,3553,3958,7099,4282,595,6869,5173,729230,6347,1958,3569	RTN4,PTPRZ1,CHST11,TNF,IL1A,MIR23B,CDKN1B,PRKCA,CXCL10,FCGR2A,FKBP1A,IFNG,LEP,EPHA4,PLA2G5,AQP4,MYC,TNFSF13,CDK4,CDC42,PPP3CA,LTB,CXCL8,RGMA,TP53,FOS,RB1,ROCK2,CDK1,ICAM1,GJA1,IL2,MMP9,CD47,GADD45A,APEX1,BTG2,IL4,SOX9,RHOB,OMG,CXCL1,AIF1,IL1B,LGALS3,TLR4,MIF,CCND1,TACR1,PDYN,CCR2,CCL2,EGR1,IL6
WP127	IL-5 Signaling Pathway	0.0233476818316976	-3.75725757895215	40	21	0.0109947643979058	1910	5310	3725,3845,2931,161742,5894,5604,2353,5294,207,5296,3717,5781,6772,6464,6850,4609,6776,2002,5295,3558,3716	JUN,KRAS,GSK3A,SPRED1,RAF1,MAP2K1,FOS,PIK3CG,AKT1,PIK3R2,JAK2,PTPN11,STAT1,SHC1,SYK,MYC,STAT5A,ELK1,PIK3R1,IL2,JAK1
WP408	Oxidative Stress	0.0242153793123425	-3.7207673388952	31	17	0.00890052356020942	1910	5310	7296,6667,6649,2729,6647,10587,2876,2878,4790,3726,1728,4501,1543,6648,4780,2353,5602	TXNRD1,SP1,SOD3,GCLC,SOD1,TXNRD2,GPX1,GPX3,NFKB1,JUNB,NQO1,MT1X,CYP1A1,SOD2,NFE2L2,FOS,MAPK10
WP2446	Retinoblastoma (RB) in Cancer	0.0250978949190641	-3.68497130412787	88	41	0.0214659685863874	1910	5310	5984,896,6118,5925,7157,890,2189,5111,983,4173,1021,1019,8317,6119,7029,4193,3146,4609,595,5983,79027,3015,7298,4172,8819,891,4175,11124,5877,5894,1026,5931,6839,3275,1027,25942,5985,2956,5928,1633,6240	RFC4,CCND3,RPA2,RB1,TP53,CCNA2,FANCG,PCNA,CDK1,MCM4,CDK6,CDK4,CDC7,RPA3,TFDP2,MDM2,HMGB1,MYC,CCND1,RFC3,ZNF655,H2AZ1,TYMS,MCM3,SAP30,CCNB1,MCM6,FAF1,RABIF,RAF1,CDKN1A,RBBP7,SUV39H1,PRMT2,CDKN1B,SIN3A,RFC5,MSH6,RBBP4,DCK,RRM1
WP2034	Leptin signaling pathway	0.026123597433032	-3.64491625691224	76	36	0.018848167539267	1910	5310	5295,2002,595,6464,6772,3551,8835,998,2931,581,6093,9475,207,9021,5604,1385,598,3953,6667,5781,3716,4790,1154,31,5770,5728,1977,3265,572,3553,3952,5296,3717,1073,5894,6714	PIK3R1,ELK1,CCND1,SHC1,STAT1,IKBKB,SOCS2,CDC42,GSK3A,BAX,ROCK1,ROCK2,AKT1,SOCS3,MAP2K1,CREB1,BCL2L1,LEPR,SP1,PTPN11,JAK1,NFKB1,CISH,ACACA,PTPN1,PTEN,EIF4E,HRAS,BAD,IL1B,LEP,PIK3R2,JAK2,CFL2,RAF1,SRC
WP2037	Prolactin Signaling Pathway	0.026123597433032	-3.64491625691224	76	36	0.018848167539267	1910	5310	3265,4792,5478,7532,5770,3725,7534,867,5294,3717,5296,6714,5894,1509,5479,5290,5781,5617,7410,3716,4793,4790,1154,3659,2353,9021,207,116986,5604,6776,4609,2002,5295,6772,6464,8835	HRAS,NFKBIA,PPIA,YWHAG,PTPN1,JUN,YWHAZ,CBL,PIK3CG,JAK2,PIK3R2,SRC,RAF1,CTSD,PPIB,PIK3CA,PTPN11,PRL,VAV2,JAK1,NFKBIB,NFKB1,CISH,IRF1,FOS,SOCS3,AKT1,AGAP2,MAP2K1,STAT5A,MYC,ELK1,PIK3R1,STAT1,SHC1,SOCS2
WP366	TGF-beta Signaling Pathway	0.0266874937033853	-3.62356022393204	133	59	0.0308900523560209	1910	5310	6711,11059,857,2353,7157,6093,983,4233,4609,4087,6464,467,998,1278,1874,6714,2033,50855,10987,7329,9972,50943,7071,163126,4088,7041,207,5604,5608,5606,4089,5295,7189,4205,7015,595,6500,57559,3726,5371,7341,10454,1387,3725,5296,57154,79753,1026,4208,7048,5596,5894,6667,4435,9146,3673,5062,25942,8554	SPTBN1,WWP1,CAV1,FOS,TP53,ROCK1,CDK1,MET,MYC,SMAD2,SHC1,ATF3,CDC42,COL1A2,E2F4,SRC,EP300,PARD6A,COPS5,UBE2I,NUP153,FOXP3,KLF10,EID2,SMAD3,TGFB1I1,AKT1,MAP2K1,MAP2K6,MAP2K3,SMAD4,PIK3R1,TRAF6,MEF2A,TERT,CCND1,SKP1,STAMBPL1,JUNB,PML,SUMO1,TAB1,CREBBP,JUN,PIK3R2,SMURF1,SNIP1,CDKN1A,MEF2C,TGFBR2,MAPK4,RAF1,SP1,CITED1,HGS,ITGA2,PAK2,SIN3A,PIAS1
WP1425	Bone Morphogenic Protein (BMP) Signalling and Regulation	0.0300747356632616	-3.5040698064115	12	8	0.00418848167539267	1910	5310	658,4086,659,657,4089,9241,10766,57154	BMPR1B,SMAD1,BMPR2,BMPR1A,SMAD4,NOG,TOB2,SMURF1
WP2018	RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway	0.0305981602166556	-3.48681539547001	55	27	0.0141361256544503	1910	5310	5295,7189,6772,4286,3551,998,7186,8878,1513,2353,207,23118,3383,5604,5608,6850,7185,9060,54,4790,10454,4792,3725,208,867,5296,6714	PIK3R1,TRAF6,STAT1,MITF,IKBKB,CDC42,TRAF2,SQSTM1,CTSK,FOS,AKT1,TAB2,ICAM1,MAP2K1,MAP2K6,SYK,TRAF1,PAPSS2,ACP5,NFKB1,TAB1,NFKBIA,JUN,AKT2,CBL,PIK3R2,SRC
WP138	Androgen receptor signaling pathway	0.0373415230038486	-3.28764935423788	90	41	0.0214659685863874	1910	5310	5728,7341,3725,1387,388,5296,6714,367,1026,6667,2033,2288,354,1499,7329,10273,8554,25942,23028,4088,7041,857,7337,9475,207,6093,5925,1385,672,5295,5052,56924,11034,4089,595,5901,9604,998,6605,4193,811	PTEN,SUMO1,JUN,CREBBP,RHOB,PIK3R2,SRC,AR,CDKN1A,SP1,EP300,FKBP4,KLK3,CTNNB1,UBE2I,STUB1,PIAS1,SIN3A,KDM1A,SMAD3,TGFB1I1,CAV1,UBE3A,ROCK2,AKT1,ROCK1,RB1,CREB1,BRCA1,PIK3R1,PRDX1,PAK6,DSTN,SMAD4,CCND1,RAN,RNF14,CDC42,SMARCE1,MDM2,CALR
WP2332	Interleukin-11 Signaling Pathway	0.0386680693334813	-3.25274110133594	44	22	0.0115183246073298	1910	5310	5894,332,6714,3717,5296,3265,7525,8554,3716,632,5781,3673,5604,1385,3383,207,9021,3572,466,3551,6772,5295	RAF1,BIRC5,SRC,JAK2,PIK3R2,HRAS,YES1,PIAS1,JAK1,BGLAP,PTPN11,ITGA2,MAP2K1,CREB1,ICAM1,AKT1,SOCS3,IL6ST,ATF1,IKBKB,STAT1,PIK3R1
WP2377	Integrated Pancreatic Cancer Pathway	0.0401429833947381	-3.215307613644	197	83	0.043455497382199	1910	5310	6667,5610,2958,8554,355,823,5371,1647,5728,2246,3725,572,1387,3326,1026,367,5350,1605,5894,5596,4089,6776,2281,1471,595,356,5243,9821,4193,3726,43,7422,2931,7186,581,3845,9232,1958,4331,207,4830,3479,1676,672,6009,5604,5290,5906,6240,2033,375,1499,7124,2100,3486,1027,5578,4790,4792,2280,2512,1874,5273,27306,6714,4690,4609,4087,7298,6772,51719,3562,100506742,1019,820,2260,7150,6794,2146,7157,5111,890,1385	SP1,EIF2AK2,GTF2A2,PIAS1,FAS,CAPN1,PML,GADD45A,PTEN,FGF1,JUN,BAD,CREBBP,HSP90AB1,CDKN1A,AR,PLN,DAG1,RAF1,MAPK4,SMAD4,STAT5A,FKBP1B,CST3,CCND1,FASLG,ABCB1,RB1CC1,MDM2,JUNB,ACHE,VEGFA,GSK3A,TRAF2,BAX,KRAS,PTTG1,EGR1,MNAT1,AKT1,NME1,IGF1,DFFA,BRCA1,RHEB,MAP2K1,PIK3CA,RAP1A,RRM1,EP300,ARF1,CTNNB1,TNF,ESR2,IGFBP3,CDKN1B,PRKCA,NFKB1,NFKBIA,FKBP1A,FTL,E2F4,SERPINB10,HPGDS,SRC,NCK1,MYC,SMAD2,TYMS,STAT1,CAB39,IL3,CASP12,CDK4,CAMP,FGFR1,TOP1,STK11,EZH2,TP53,PCNA,CCNA2,CREB1
WP286	IL-3 Signaling Pathway	0.0413172786774236	-3.18647449659404	49	24	0.012565445026178	1910	5310	3562,6776,5295,6464,1399,2353,7529,207,598,5604,1232,3576,3716,5781,6850,867,5296,3717,6714,5894,942,3265,572,3725	IL3,STAT5A,PIK3R1,SHC1,CRKL,FOS,YWHAB,AKT1,BCL2L1,MAP2K1,CCR3,CXCL8,JAK1,PTPN11,SYK,CBL,PIK3R2,JAK2,SRC,RAF1,CD86,HRAS,BAD,JUN
WP69	T-Cell antigen Receptor (TCR)  Signaling Pathway	0.0449578880618031	-3.10202904821434	91	41	0.0214659685863874	1910	5310	6464,1399,8915,3551,5295,7189,3972,4690,3601,998,5588,3702,919,9308,4988,1234,3569,1385,5604,207,2353,917,5781,920,3604,3662,4790,355,3552,9020,3725,3553,4792,3937,3265,5894,29851,940,9402,5296,867	SHC1,CRKL,BCL10,IKBKB,PIK3R1,TRAF6,LHB,NCK1,IL15RA,CDC42,PRKCQ,ITK,CD247,CD83,OPRM1,CCR5,IL6,CREB1,MAP2K1,AKT1,FOS,CD3G,PTPN11,CD4,TNFRSF9,IRF4,NFKB1,FAS,IL1A,MAP3K14,JUN,IL1B,NFKBIA,LCP2,HRAS,RAF1,ICOS,CD28,GRAP2,PIK3R2,CBL
WP706	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	0.0456192761226652	-3.08742492979529	162	69	0.0361256544502618	1910	5310	4790,2100,3552,55800,7124,7533,2784,1499,406992,5354,6532,2033,1139,4800,5316,5567,7534,4915,2597,3764,55536,1141,361,1385,3356,6616,3576,121278,6711,3329,2697,2328,9722,406950,291,6750,6667,3030,406919,7018,367,4204,4208,4824,6844,2554,7433,3725,1387,5460,3553,7532,8553,3586,6507,6640,6869,6863,6657,3350,859,3596,478,3569,1958,7529,11076,7184,7422	NFKB1,ESR2,IL1A,SCN3B,TNF,YWHAH,GNB3,CTNNB1,MIR210,PLP1,SLC6A4,EP300,CHRNA7,NFYA,PKNOX1,PRKACB,YWHAZ,NTRK2,GAPDH,KCNJ8,CDCA7L,CHRNB2,AQP4,CREB1,HTR2A,SNAP25,CXCL8,TPH2,SPTBN1,HSPD1,GJA1,FMO3,NOS1AP,MIR16-1,SLC25A4,SST,SP1,HADHA,MIR130A,TF,AR,MECP2,MEF2C,NKX3-1,VAMP2,GABRA1,VIPR1,JUN,CREBBP,POU5F1,IL1B,YWHAG,BHLHE40,IL10,SLC1A3,SNTA1,TACR1,TAC1,SOX2,HTR1A,CAV3,IL13,ATP1A3,IL6,EGR1,YWHAB,TPPP,HSP90B1,VEGFA
WP453	Inflammatory Response Pathway	0.0481638409935247	-3.03314672631289	33	17	0.00890052356020942	1910	5310	3565,3560,3458,1278,942,3567,1281,940,941,3559,958,3913,3561,7059,959,7133,3558	IL4,IL2RB,IFNG,COL1A2,CD86,IL5,COL3A1,CD28,CD80,IL2RA,CD40,LAMB2,IL2RG,THBS3,CD40LG,TNFRSF1B,IL2
WP262	EBV LMP1 signaling	0.0519723398184065	-2.95704362849294	24	13	0.00680628272251309	1910	5310	9020,4790,7185,6364,6352,7124,3456,3551,3320,4792,4215,3576,7189	MAP3K14,NFKB1,TRAF1,CCL20,CCL5,TNF,IFNB1,IKBKB,HSP90AA1,NFKBIA,MAP3K3,CXCL8,TRAF6
WP3594	Circadian rythm related genes	0.0523917315158922	-2.9490064956044	207	86	0.0450261780104712	1910	5310	15,355,9099,9967,10911,8553,7311,3725,2776,1128,8403,85457,4783,1859,9607,10419,4887,57805,2155,7071,1407,6532,3952,134,148523,23291,1019,1812,7157,5501,84432,5602,2063,121278,3184,2146,26224,5500,25942,468,51738,2673,6233,6440,6839,5371,5728,1814,5629,22871,4987,2767,6500,1471,8841,9456,1958,1660,3569,55269,5730,9370,3778,5468,2033,2837,4841,4916,6928,3400,3751,687,1141,7298,55366,6096,6770,9475,1364,1385,1655,50865,1454,7150,7337,5465	AANAT,FAS,USP2,THRAP3,UTS2,BHLHE40,UBA52,JUN,GNAQ,CHRM1,SOX14,CIPC,NFIL3,DYRK1A,CARTPT,PRMT5,NPY2R,CCAR2,F7,KLF10,CRY1,SLC6A4,LEP,ADORA1,CIART,FBXW11,CDK4,DRD1,TP53,PPP1CC,PROK1,MAPK10,NR2F6,TPH2,HNRNPD,EZH2,FBXL3,PPP1CB,SIN3A,ATF4,GHRL,GFPT1,RPS27A,SFTPC,SUV39H1,PML,PTEN,DRD3,PROX1,NLGN1,OPRL1,GNA11,SKP1,CST3,HDAC3,HOMER1,EGR1,DHX9,IL6,PSPC1,PTGDS,ADIPOQ,KCNMA1,PPARG,EP300,UTS2R,NONO,NTRK3,HNF1B,ID4,KCND2,KLF9,CHRNB2,TYMS,LGR4,RORB,STAR,ROCK2,CLDN4,CREB1,DDX5,HEBP1,CSNK1E,TOP1,UBE3A,PPARA
WP2637	Structural Pathway of Interleukin 1 (IL-1)	0.0530767518837355	-2.93601626423647	50	24	0.012565445026178	1910	5310	3551,4609,2002,7189,4615,23118,5604,5606,3665,5608,2353,5602,4215,51135,9020,3552,54472,4790,3556,4793,10010,1977,10454,4792	IKBKB,MYC,ELK1,TRAF6,MYD88,TAB2,MAP2K1,MAP2K3,IRF7,MAP2K6,FOS,MAPK10,MAP3K3,IRAK4,MAP3K14,IL1A,TOLLIP,NFKB1,IL1RAP,NFKBIB,TANK,EIF4E,TAB1,NFKBIA
WP364	IL-6 signaling pathway	0.0560808096612476	-2.88096159874862	43	21	0.0109947643979058	1910	5310	3659,3572,572,1387,9021,3717,207,5296,2063,3569,5604,598,5295,7076,2549,6772,5781,6464,3716,7432,3726	IRF1,IL6ST,BAD,CREBBP,SOCS3,JAK2,AKT1,PIK3R2,NR2F6,IL6,MAP2K1,BCL2L1,PIK3R1,TIMP1,GAB1,STAT1,PTPN11,SHC1,JAK1,VIP,JUNB
WP3872	Regulation of Apoptosis by Parathyroid Hormone-related Protein	0.0575656483943306	-2.85482927122967	22	12	0.00628272251308901	1910	5310	4609,578,2931,581,5744,666,207,3655,5294,4170,598,597	MYC,BAK1,GSK3A,BAX,PTHLH,BOK,AKT1,ITGA6,PIK3CG,MCL1,BCL2L1,BCL2A1
WP1455	Serotonin Transporter Activity	0.0577028638619783	-2.85244847304332	11	7	0.00366492146596859	1910	5310	7041,5516,10066,121278,6532,3553,6804	TGFB1I1,PPP2CB,SCAMP2,TPH2,SLC6A4,IL1B,STX1A
WP2583	T-Cell Receptor and Co-stimulatory Signaling	0.059390629205397	-2.82361882254346	29	15	0.00785340314136126	1910	5310	940,1859,207,1452,5133,2931,5530,5728,4792,4790,5578,8445,3702,3558,1493	CD28,DYRK1A,AKT1,CSNK1A1,PDCD1,GSK3A,PPP3CA,PTEN,NFKBIA,NFKB1,PRKCA,DYRK2,ITK,IL2,CTLA4
WP107	Translation Factors	0.0606893078659955	-2.80198774361536	53	25	0.0130890052356021	1910	5310	1964,26986,7458,1979,1977,8669,8891,2107,1915,10605,8666,8664,5610,1974,1933,8893,9669,1975,1937,8637,1938,8894,1965,3646,8892	EIF1AX,PABPC1,EIF4H,EIF4EBP2,EIF4E,EIF3J,EIF2B3,ETF1,EEF1A1,PAIP1,EIF3G,EIF3D,EIF2AK2,EIF4A2,EEF1B2,EIF2B5,EIF5B,EIF4B,EEF1G,EIF4EBP3,EEF2,EIF2S2,EIF2S1,EIF3E,EIF2B2
WP696	Benzo(a)pyrene metabolism	0.0608150808021061	-2.79991748125841	9	6	0.0031413612565445	1910	5310	1543,1545,1646,2052,10327,1645	CYP1A1,CYP1B1,AKR1C2,EPHX1,AKR1A1,AKR1C1
WP678	Arachidonate Epoxygenase / Epoxide Hydrolase	0.0622037929437805	-2.77733930129265	7	5	0.00261780104712042	1910	5310	2950,1351,9377,1558,1559	GSTP1,COX8A,COX5A,CYP2C8,CYP2C9
WP1742	TP53 Network	0.0637919428976358	-2.75212838347716	20	11	0.00575916230366492	1910	5310	8743,7341,1647,581,666,7157,5015,1026,5366,4609,4193	TNFSF10,SUMO1,GADD45A,BAX,BOK,TP53,OTX2,CDKN1A,PMAIP1,MYC,MDM2
WP2374	Oncostatin M Signaling Pathway	0.0700757213693887	-2.65817888773684	66	30	0.0157068062827225	1910	5310	3265,4792,5579,6714,5894,3717,5781,5008,5581,1027,5578,4790,3716,3949,3572,3845,7422,5604,1385,7157,2353,9021,6347,1958,207,6772,6464,7078,5295,3726	HRAS,NFKBIA,PRKCB,SRC,RAF1,JAK2,PTPN11,OSM,PRKCE,CDKN1B,PRKCA,NFKB1,JAK1,LDLR,IL6ST,KRAS,VEGFA,MAP2K1,CREB1,TP53,FOS,SOCS3,CCL2,EGR1,AKT1,STAT1,SHC1,TIMP3,PIK3R1,JUNB
WP727	Monoamine Transport	0.0722075637446139	-2.62821047756468	32	16	0.00837696335078534	1910	5310	7124,114907,1621,43,6529,6531,5819,6532,6530,6804,7041,5516,10066,121278,3553,11255	TNF,FBXO32,DBH,ACHE,SLC6A1,SLC6A3,NECTIN2,SLC6A4,SLC6A2,STX1A,TGFB1I1,PPP2CB,SCAMP2,TPH2,IL1B,HRH3
WP3286	Copper homeostasis	0.0755561738157581	-2.58287887532606	54	25	0.0130890052356021	1910	5310	10063,4502,4504,9973,3725,5621,4493,5728,1317,6667,4500,4520,5290,1353,4891,7157,23621,207,4501,4193,4489,54739,595,6649,6647	COX17,MT2A,MT3,CCS,JUN,PRNP,MT1E,PTEN,SLC31A1,SP1,MT1L,MTF1,PIK3CA,COX11,SLC11A2,TP53,BACE1,AKT1,MT1X,MDM2,MT1A,XAF1,CCND1,SOD3,SOD1
WP176	Folate Metabolism	0.0771416361409452	-2.56211211640695	69	31	0.0162303664921466	1910	5310	6347,7157,3383,3569,2879,2877,2350,6648,2876,2878,213,2147,2348,6647,257202,6649,6470,5340,390243,3458,3039,3553,3565,3949,7124,3558,4790,2155,12,10588,3043	CCL2,TP53,ICAM1,IL6,GPX4,GPX2,FOLR2,SOD2,GPX1,GPX3,ALB,F2,FOLR1,SOD1,GPX6,SOD3,SHMT1,PLG,IZUMO1R,IFNG,HBA1,IL1B,IL4,LDLR,TNF,IL2,NFKB1,F7,SERPINA3,MTHFS,HBB
WP2453	TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)	0.0784247564778863	-2.54561563006946	16	9	0.00471204188481675	1910	5310	48,4190,5160,1737,8801,5091,3419,1743,3417	ACO1,MDH1,PDHA1,DLAT,SUCLG2,PC,IDH3A,DLST,IDH1
WP2036	TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway	0.0797792342872725	-2.52849203035399	42	20	0.0104712041884817	1910	5310	4790,9020,4318,8742,4793,7124,84676,1499,7185,6352,3551,329,3569,5894,207,6347,208,3725,4792,7186	NFKB1,MAP3K14,MMP9,TNFSF12,NFKBIB,TNF,TRIM63,CTNNB1,TRAF1,CCL5,IKBKB,BIRC2,IL6,RAF1,AKT1,CCL2,AKT2,JUN,NFKBIA,TRAF2
WP3844	PI3K-AKT-mTOR signaling pathway and therapeutic opportunities	0.080416632962738	-2.52053424654745	30	15	0.00785340314136126	1910	5310	5295,5290,9821,1027,5728,8503,3265,3845,572,207,5296,5294,2887,7942,6009	PIK3R1,PIK3CA,RB1CC1,CDKN1B,PTEN,PIK3R3,HRAS,KRAS,BAD,AKT1,PIK3R2,PIK3CG,GRB10,TFEB,RHEB
WP702	Metapathway biotransformation	0.0805825707054899	-2.5184728972025	177	73	0.0382198952879581	1910	5310	2052,79807,1577,1594,2948,2946,2326,2328,83539,373156,1585,8534,3176,9348,1545,1572,9653,2949,1581,1593,1312,9435,9486,51302,9957,80218,3340,1589,119391,2941,1558,11283,1565,120227,1584,1586,1543,64816,10327,26151,2877,9446,1559,1646,1592,54658,50515,9955,653689,1562,122830,79799,79690,2327,2947,2950,10,285440,27284,9514,231,126410,56548,2878,4259,166012,8574,10249,1645,66002,4258,7881,2879	EPHX1,GSTCD,CYP3A5,CYP27B1,GSTM4,GSTM2,FMO1,FMO3,CHST9,GSTK1,CYP11B2,CHST1,HNMT,NDST3,CYP1B1,CYP2F1,HS2ST1,GSTM5,CYP7A1,CYP27A1,COMT,CHST2,CHST10,CYP39A1,HS3ST1,NAA50,NDST1,CYP21A2,GSTO2,GSTA4,CYP2C8,CYP4F8,CYP2D6,CYP2R1,CYP11B1,CYP17A1,CYP1A1,CYP3A43,AKR1A1,NAT9,GPX2,GSTO1,CYP2C9,AKR1C2,CYP26A1,UGT1A1,CHST11,HS3ST3A1,GSTT2B,CYP2C18,NAA30,UGT2A3,GAL3ST4,FMO2,GSTM3,GSTP1,NAT2,CYP4V2,SULT1B1,GAL3ST1,AKR1B1,CYP4F22,CHST7,GPX3,MGST3,CHST13,AKR7A2,GLYAT,AKR1C1,CYP4F12,MGST2,KCNAB1,GPX4
WP2328	Allograft Rejection	0.0906735868087664	-2.40048917917017	80	35	0.0183246073298429	1910	5310	6366,3558,7124,6373,959,355,3552,50943,1493,3559,940,942,59067,3586,6363,3553,3458,3565,356,5243,50616,3596,6772,6387,3592,958,4283,941,2551,3567,10376,10563,3593,7422,3576	CCL21,IL2,TNF,CXCL11,CD40LG,FAS,IL1A,FOXP3,CTLA4,IL2RA,CD28,CD86,IL21,IL10,CCL19,IL1B,IFNG,IL4,FASLG,ABCB1,IL22,IL13,STAT1,CXCL12,IL12A,CD40,CXCL9,CD80,GABPA,IL5,TUBA1B,CXCL13,IL12B,VEGFA,CXCL8
WP395	IL-4 Signaling Pathway	0.0927192577589921	-2.37817908517043	55	25	0.0130890052356021	1910	5310	3561,5290,2033,5781,3716,4790,4792,3565,572,867,3717,5296,332,6778,2002,6776,5295,6772,3551,6464,9655,4783,9021,2353,207	IL2RG,PIK3CA,EP300,PTPN11,JAK1,NFKB1,NFKBIA,IL4,BAD,CBL,JAK2,PIK3R2,BIRC5,STAT6,ELK1,STAT5A,PIK3R1,STAT1,IKBKB,SHC1,SOCS5,NFIL3,SOCS3,FOS,AKT1
WP23	B Cell Receptor Signaling Pathway	0.0931474938280447	-2.37357108698736	98	42	0.0219895287958115	1910	5310	2969,7462,5880,118788,2931,5608,5604,1385,207,6464,1399,3551,975,8915,974,5295,4690,2002,4609,998,3725,8394,25780,4792,3265,5894,5596,5579,4208,5294,5296,867,6850,5781,3662,2549,3608,604,4149,4790,7410,3059	GTF2I,LAT2,RAC2,PIK3AP1,GSK3A,MAP2K6,MAP2K1,CREB1,AKT1,SHC1,CRKL,IKBKB,CD81,BCL10,CD79B,PIK3R1,NCK1,ELK1,MYC,CDC42,JUN,PIP5K1A,RASGRP3,NFKBIA,HRAS,RAF1,MAPK4,PRKCB,MEF2C,PIK3CG,PIK3R2,CBL,SYK,PTPN11,IRF4,GAB1,ILF2,BCL6,MAX,NFKB1,VAV2,HCLS1
WP2007	Iron metabolism in placenta	0.0963822433396507	-2.33943329205359	12	7	0.00366492146596859	1910	5310	3658,7037,57192,2495,7018,4891,48	IREB2,TFRC,MCOLN1,FTH1,TF,SLC11A2,ACO1
WP2290	RalA downstream regulated genes	0.0963822433396507	-2.33943329205359	12	7	0.00366492146596859	1910	5310	3265,149371,5880,55770,998,5898,3845	HRAS,EXOC8,RAC2,EXOC2,CDC42,RALA,KRAS
WP3849	MAPK  and NFkB Signalling Pathways Inhibited by Yersinia YopJ	0.0963822433396507	-2.33943329205359	12	7	0.00366492146596859	1910	5310	3551,4792,7189,4790,5608,5894,9020	IKBKB,NFKBIA,TRAF6,NFKB1,MAP2K6,RAF1,MAP3K14
WP2261	Signaling Pathways in Glioblastoma	0.0976038522086175	-2.3268383169914	83	36	0.018848167539267	1910	5310	4233,672,5606,5608,5604,10000,7157,5925,207,3845,1021,4193,5588,2260,1019,595,5295,1026,5579,6714,54206,5894,867,208,5294,5296,3480,3265,5728,1027,5578,1031,2033,2956,5290,2549	MET,BRCA1,MAP2K3,MAP2K6,MAP2K1,AKT3,TP53,RB1,AKT1,KRAS,CDK6,MDM2,PRKCQ,FGFR1,CDK4,CCND1,PIK3R1,CDKN1A,PRKCB,SRC,ERRFI1,RAF1,CBL,AKT2,PIK3CG,PIK3R2,IGF1R,HRAS,PTEN,CDKN1B,PRKCA,CDKN2C,EP300,MSH6,PIK3CA,GAB1
WP2447	Amyotrophic lateral sclerosis (ALS)	0.0982416419784283	-2.32032510077318	38	18	0.00942408376963351	1910	5310	2876,100506742,4747,7124,2890,1471,79139,6647,5608,6506,598,7157,9973,572,581,5530,10452,5868	GPX1,CASP12,NEFL,TNF,GRIA1,CST3,DERL1,SOD1,MAP2K6,SLC1A2,BCL2L1,TP53,CCS,BAD,BAX,PPP3CA,TOMM40,RAB5A
WP2849	Hematopoietic Stem Cell Differentiation	0.101604637110432	-2.28666610402856	48	22	0.0115183246073298	1910	5310	2353,1437,3567,406942,3569,4005,3562,2815,6776,91,10661,861,4601,406919,3553,3552,7852,23650,406950,2056,407006,4778	FOS,CSF2,IL5,MIR150,IL6,LMO2,IL3,GP9,STAT5A,ACVR1B,KLF1,RUNX1,MXI1,MIR130A,IL1B,IL1A,CXCR4,TRIM29,MIR16-1,EPO,MIR221,NFE2
WP2873	Aryl Hydrocarbon Receptor Pathway	0.101604637110432	-2.28666610402856	48	22	0.0115183246073298	1910	5310	3593,4780,581,10486,1543,10728,3726,3592,9049,6714,3725,3458,3553,1545,2939,1027,1728,7124,3558,54658,2033,3320	IL12B,NFE2L2,BAX,CAP2,CYP1A1,PTGES3,JUNB,IL12A,AIP,SRC,JUN,IFNG,IL1B,CYP1B1,GSTA2,CDKN1B,NQO1,TNF,IL2,UGT1A1,EP300,HSP90AA1
WP43	Oxidation by Cytochrome P450	0.10172103673793	-2.28552114640456	63	28	0.0146596858638743	1910	5310	1543,1586,1584,120227,1565,5447,1559,66002,51706,64816,51302,11283,1558,126410,80777,1572,1545,285440,1727,1593,1581,1577,1594,1592,1528,1562,1585,51167	CYP1A1,CYP17A1,CYP11B1,CYP2R1,CYP2D6,POR,CYP2C9,CYP4F12,CYB5R1,CYP3A43,CYP39A1,CYP4F8,CYP2C8,CYP4F22,CYB5B,CYP2F1,CYP1B1,CYP4V2,CYB5R3,CYP27A1,CYP7A1,CYP3A5,CYP27B1,CYP26A1,CYB5A,CYP2C18,CYP11B2,CYB5R4
WP3656	Interleukin-1 Induced Activation of NF-kappa-B	0.106633830212101	-2.23835446101103	10	6	0.0031413612565445	1910	5310	8878,7334,7335,3552,7189,92610	SQSTM1,UBE2N,UBE2V1,IL1A,TRAF6,TIFA
WP2884	NRF2 pathway	0.106772163439111	-2.23705802838495	143	59	0.0308900523560209	1910	5310	3320,6532,54658,874,221223,4097,2512,2947,2495,2950,7042,6530,7295,6649,23657,7296,55334,91252,2878,6529,4259,8878,7922,4258,4780,9588,6534,6538,6513,2946,2948,57181,1728,1969,2939,2258,2949,8884,177,2539,29988,3326,2938,7048,6533,6515,5052,2729,1839,114112,2941,29985,5265,1244,6531,10057,1958,6535,2877	HSP90AA1,SLC6A4,UGT1A1,CBR3,CES5A,MAFG,FTL,GSTM3,FTH1,GSTP1,TGFB2,SLC6A2,TXN,SOD3,SLC7A11,TXNRD1,SLC39A9,SLC39A13,GPX3,SLC6A1,MGST3,SQSTM1,SLC39A7,MGST2,NFE2L2,PRDX6,SLC6A7,SLC6A11,SLC2A1,GSTM2,GSTM4,SLC39A10,NQO1,EPHA2,GSTA2,FGF13,GSTM5,SLC5A6,AGER,G6PD,SLC2A8,HSP90AB1,GSTA1,TGFBR2,SLC6A6,SLC2A3,PRDX1,GCLC,HBEGF,TXNRD3,GSTA4,SLC39A3,SERPINA1,ABCC2,SLC6A3,ABCC5,EGR1,SLC6A8,GPX2
WP2324	AGE/RAGE pathway	0.11053829901922	-2.20239322061635	66	29	0.0151832460732984	1910	5310	4323,4088,5604,207,6093,3551,249,6772,6464,6776,4087,6647,4615,998,3725,177,4792,5579,6714,4478,5894,3958,3717,6667,4318,114609,51135,5578,4790	MMP14,SMAD3,MAP2K1,AKT1,ROCK1,IKBKB,ALPL,STAT1,SHC1,STAT5A,SMAD2,SOD1,MYD88,CDC42,JUN,AGER,NFKBIA,PRKCB,SRC,MSN,RAF1,LGALS3,JAK2,SP1,MMP9,TIRAP,IRAK4,PRKCA,NFKB1
WP3658	Wnt/beta-catenin Signaling Pathway in Leukemia	0.112095296940459	-2.18840590392811	24	12	0.00628272251308901	1910	5310	1452,4040,5371,607,22943,207,595,11197,8323,3728,7704,1499	CSNK1A1,LRP6,PML,BCL9,DKK1,AKT1,CCND1,WIF1,FZD6,JUP,ZBTB16,CTNNB1
WP3646	Hepatitis C and Hepatocellular Carcinoma	0.112524277765501	-2.18458627825964	51	23	0.0120418848167539	1910	5310	2487,5781,407012,7410,3716,4790,2017,3725,1026,332,4089,4609,3577,595,356,7422,3576,4088,7157,207,672,3569,598	FRZB,PTPN11,MIR24-1,VAV2,JAK1,NFKB1,CTTN,JUN,CDKN1A,BIRC5,SMAD4,MYC,CXCR1,CCND1,FASLG,VEGFA,CXCL8,SMAD3,TP53,AKT1,BRCA1,IL6,BCL2L1
WP382	MAPK Signaling Pathway	0.116739490561757	-2.14781040308652	170	69	0.0361256544502618	1910	5310	5880,8649,5530,10000,3316,23118,5602,5495,2353,7157,1399,2002,4609,22808,5322,2260,998,4296,84867,8550,1649,5579,7042,208,3315,5908,6788,5906,4790,929,3552,6655,7124,1843,3845,7186,5604,5608,5606,207,130399,3312,3551,91,7189,1848,356,5536,7786,11221,3725,3553,7850,10454,1647,5535,7048,5596,5894,4208,4909,5062,7043,4068,468,4149,355,9020,3309	RAC2,LAMTOR3,PPP3CA,AKT3,HSPB2,TAB2,MAPK10,PPM1B,FOS,TP53,CRKL,ELK1,MYC,MRAS,PLA2G5,FGFR1,CDC42,MAP3K11,PTPN5,MAPKAPK5,DDIT3,PRKCB,TGFB2,AKT2,HSPB1,RAP1B,STK3,RAP1A,NFKB1,CD14,IL1A,SOS2,TNF,DUSP1,KRAS,TRAF2,MAP2K1,MAP2K6,MAP2K3,AKT1,ACVR1C,HSPA8,IKBKB,ACVR1B,TRAF6,DUSP6,FASLG,PPP5C,MAP3K12,DUSP10,JUN,IL1B,IL1R2,TAB1,GADD45A,PPP3R2,TGFBR2,MAPK4,RAF1,MEF2C,NTF4,PAK2,TGFB3,SH2D1A,ATF4,MAX,FAS,MAP3K14,HSPA5
WP2338	miRNA Biogenesis	0.117481208680546	-2.14147688431049	8	5	0.00261780104712042	1910	5310	5901,29102,57510,23405,54487	RAN,DROSHA,XPO5,DICER1,DGCR8
WP2276	Glial Cell Differentiation	0.117481208680546	-2.14147688431049	8	5	0.00261780104712042	1910	5310	5354,4478,1267,406989,11076	PLP1,MSN,CNP,MIR206,TPPP
WP2866	mir34a and TGIF2 in osteoclastogenesis	0.129339759546243	-2.04531254204812	2	2	0.00104712041884817	1910	5310	60436,407040	TGIF2,MIR34A
WP2435	Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis	0.129358367894323	-2.04516868056527	15	8	0.00418848167539267	1910	5310	4792,4097,7422,3725,3551,2353,4790,4780	NFKBIA,MAFG,VEGFA,JUN,IKBKB,FOS,NFKB1,NFE2L2
WP2828	Bladder Cancer	0.135235479277432	-2.00073772910849	32	15	0.00785340314136126	1910	5310	5295,4609,595,1612,1019,4193,3576,3265,7422,5296,7157,5925,5604,1026,1613	PIK3R1,MYC,CCND1,DAPK1,CDK4,MDM2,CXCL8,HRAS,VEGFA,PIK3R2,TP53,RB1,MAP2K1,CDKN1A,DAPK3
WP733	Serotonin Receptor 2 and STAT3 Signaling	0.135849550154041	-1.99620725445835	4	3	0.00157068062827225	1910	5310	3717,3356,2776	JAK2,HTR2A,GNAQ
WP2889	Oxytocin signaling	0.135849550154041	-1.99620725445835	4	3	0.00157068062827225	1910	5310	952,5021,2776	CD38,OXTR,GNAQ
WP1530	miRNA Regulation of DNA Damage Response	0.135940795286132	-1.99553581680761	93	39	0.0204188481675393	1910	5310	407006,406950,1020,355,1027,10912,2810,406992,4683,4616,1647,5371,406982,1026,3014,891,595,5366,4609,407041,406952,442918,4193,5810,1019,581,1021,1385,672,983,406900,6118,896,7157,554213,407007,5925,693122,693123	MIR221,MIR16-1,CDK5,FAS,CDKN1B,GADD45G,SFN,MIR210,NBN,GADD45B,GADD45A,PML,MIR20A,CDKN1A,H2AX,CCNB1,CCND1,PMAIP1,MYC,MIR34B,MIR17,MIR373,MDM2,RAD1,CDK4,BAX,CDK6,CREB1,BRCA1,CDK1,MIR106B,RPA2,CCND3,TP53,MIR449A,MIR222,RB1,MIR421,MIR449B
WP466	DNA Replication	0.13718769124874	-1.98640528164536	42	19	0.00994764397905759	1910	5310	4173,5111,5982,4175,6118,5984,5558,7311,5425,51053,8317,6119,5001,4172,23649,23594,5983,5985,57804	MCM4,PCNA,RFC2,MCM6,RPA2,RFC4,PRIM2,UBA52,POLD2,GMNN,CDC7,RPA3,ORC5,MCM3,POLA2,ORC6,RFC3,RFC5,POLD4
WP516	Hypertrophy Model	0.141307220261357	-1.95681889179067	20	10	0.00523560209424084	1910	5310	3552,467,11072,3458,3475,1977,2660,7422,3606,1839	IL1A,ATF3,DUSP14,IFNG,IFRD1,EIF4E,MSTN,VEGFA,IL18,HBEGF
WP536	Calcium Regulation in the Cardiac Cell	0.143823546692344	-1.93916810097812	151	61	0.0319371727748691	1910	5310	2767,8490,154,1128,5588,155,2776,2773,153,2706,3760,59345,7529,2697,2771,5569,10287,6001,5581,2782,406974,2705,5996,54331,5570,1132,10052,7532,2775,8536,5350,2787,6546,2781,108,483,811,9628,148,55970,3745,2785,818,1131,51764,481,11142,5567,5578,1133,2784,2788,7533,2810,784,7534,2791,2280,109,5579,5997	GNA11,RGS5,ADRB2,CHRM1,PRKCQ,ADRB3,GNAQ,GNAI3,ADRB1,GJB2,KCNJ3,GNB4,YWHAB,GJA1,GNAI2,PKIA,RGS19,RGS10,PRKCE,GNB1,MIR197,GJB1,RGS1,GNG2,PKIB,CHRM4,GJC1,YWHAG,GNAO1,CAMK1,PLN,GNG5,SLC8A1,GNAZ,ADCY2,ATP1B3,CALR,RGS6,ADRA1A,GNG12,KCNB1,GNG3,CAMK2G,CHRM3,GNG13,ATP1B1,PKIG,PRKACB,PRKCA,CHRM5,GNB3,GNG7,YWHAH,SFN,CACNB3,YWHAZ,GNG11,FKBP1A,ADCY3,PRKCB,RGS2
WP2881	Estrogen Receptor Pathway	0.145954343499251	-1.92446142193813	13	7	0.00366492146596859	1910	5310	57678,1543,3725,5465,1545,51,6667	GPAM,CYP1A1,JUN,PPARA,CYP1B1,ACOX1,SP1
WP1434	Osteopontin Signaling	0.145954343499251	-1.92446142193813	13	7	0.00366492146596859	1910	5310	9020,4318,6696,5604,4790,3685,3551	MAP3K14,MMP9,SPP1,MAP2K1,NFKB1,ITGAV,IKBKB
WP3876	BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation	0.145954343499251	-1.92446142193813	13	7	0.00366492146596859	1910	5310	4086,6750,6422,22943,1499,4090,4093	SMAD1,SST,SFRP1,DKK1,CTNNB1,SMAD5,SMAD9
WP1423	Ganglio Sphingolipid Metabolism	0.145954343499251	-1.92446142193813	13	7	0.00366492146596859	1910	5310	6483,6482,29906,8869,2523,8705,8708	ST3GAL2,ST3GAL1,ST8SIA5,ST3GAL5,FUT1,B3GALT4,B3GALT1
WP1984	Integrated Breast Cancer Pathway	0.14915735852794	-1.90275343281237	154	62	0.0324607329842932	1910	5310	79877,8554,4149,5245,2197,2956,6667,5569,5296,367,1605,7048,5898,5371,1647,10454,5728,572,3725,4193,60489,4089,595,10600,207,7035,672,6009,140739,7422,659,2931,466,4086,4664,581,3845,1499,3716,84640,4790,5906,2033,64781,1022,152789,25780,1019,578,998,4609,657,4087,79027,6772,7157,5925,1385,6794,571,4953,9958	DCAKD,PIAS1,MAX,PHB1,FAU,MSH6,SP1,PKIA,PIK3R2,AR,DAG1,TGFBR2,RALA,PML,GADD45A,TAB1,PTEN,BAD,JUN,MDM2,APOBEC3G,SMAD4,CCND1,USP16,AKT1,TFPI,BRCA1,RHEB,UBE2F,VEGFA,BMPR2,GSK3A,ATF1,SMAD1,NAB1,BAX,KRAS,CTNNB1,JAK1,USP38,NFKB1,RAP1A,EP300,CERK,CDK7,JAKMIP1,RASGRP3,CDK4,BAK1,CDC42,MYC,BMPR1A,SMAD2,ZNF655,STAT1,TP53,RB1,CREB1,STK11,BACH1,ODC1,USP15
WP437	EGF/EGFR Signaling Pathway	0.150275074252115	-1.8952878359488	162	65	0.0340314136125654	1910	5310	5111,1385,3636,2353,6093,857,998,382,10617,6772,1399,6464,2002,4690,9712,6812,6714,5579,2887,84867,5359,9922,2059,6655,1445,5578,7410,3716,4605,9101,5781,1072,5906,4215,5604,207,3845,466,1173,5037,4205,6776,4738,160,5295,2005,54206,4208,5898,5596,5894,867,3717,5296,3725,5868,3265,858,5728,5899,1175,2697,6667,9146,2549	PCNA,CREB1,INPPL1,FOS,ROCK1,CAV1,CDC42,ARF6,STAMBP,STAT1,CRKL,SHC1,ELK1,NCK1,USP6NL,STXBP1,SRC,PRKCB,GRB10,PTPN5,PLSCR1,IQSEC1,EPS8,SOS2,CSK,PRKCA,VAV2,JAK1,MYBL2,USP8,PTPN11,CFL1,RAP1A,MAP3K3,MAP2K1,AKT1,KRAS,ATF1,AP2M1,PEBP1,MEF2A,STAT5A,NEDD8,AP2A1,PIK3R1,ELK4,ERRFI1,MEF2C,RALA,MAPK4,RAF1,CBL,JAK2,PIK3R2,JUN,RAB5A,HRAS,CAV2,PTEN,RALB,AP2S1,GJA1,SP1,HGS,GAB1
WP1403	AMP-activated Protein Kinase (AMPK) Signaling	0.152156600387817	-1.88284502278601	68	29	0.0151832460732984	1910	5310	148,51719,1938,5295,5571,890,7157,207,2997,9370,51094,8503,6794,55437,200186,31,5567,3953,5290,1375,1026,208,891,5296,3952,5294,23236,79602,5564	ADRA1A,CAB39,EEF2,PIK3R1,PRKAG1,CCNA2,TP53,AKT1,GYS1,ADIPOQ,ADIPOR1,PIK3R3,STK11,STRADB,CRTC2,ACACA,PRKACB,LEPR,PIK3CA,CPT1B,CDKN1A,AKT2,CCNB1,PIK3R2,LEP,PIK3CG,PLCB1,ADIPOR2,PRKAB1
WP2380	Brain-Derived Neurotrophic Factor (BDNF) signaling pathway	0.157665231981381	-1.84728127868356	144	58	0.0303664921465969	1910	5310	572,3725,3265,2891,5864,8536,1977,4208,391,5894,3717,5296,1268,5604,1958,207,4205,3551,1965,1938,8894,6776,1457,8851,7189,5295,1959,10817,4915,53358,3738,4792,6714,6696,5781,1020,1072,5906,55816,4790,1499,7410,2562,8878,1385,2353,5602,249,6772,2890,6464,1739,4690,2002,7074,998,4916,10642	BAD,JUN,HRAS,GRIA2,RAB3A,CAMK1,EIF4E,MEF2C,RHOG,RAF1,JAK2,PIK3R2,CNR1,MAP2K1,EGR1,AKT1,MEF2A,IKBKB,EIF2S1,EEF2,EIF2S2,STAT5A,CSNK2A1,CDK5R1,TRAF6,PIK3R1,EGR2,FRS3,NTRK2,SHC3,KCNA3,NFKBIA,SRC,SPP1,PTPN11,CDK5,CFL1,RAP1A,DOK5,NFKB1,CTNNB1,VAV2,GABRB3,SQSTM1,CREB1,FOS,MAPK10,ALPL,STAT1,GRIA1,SHC1,DLG1,NCK1,ELK1,TIAM1,CDC42,NTRK3,IGF2BP1
WP712	Estrogen signaling pathway	0.165727887444102	-1.7974080679013	23	11	0.00575916230366492	1910	5310	3725,3551,5290,2002,6667,2782,4790,1385,5604,207,2353	JUN,IKBKB,PIK3CA,ELK1,SP1,GNB1,NFKB1,CREB1,MAP2K1,AKT1,FOS
WP2526	PDGF Pathway	0.168045977915792	-1.7835176589517	38	17	0.00890052356020942	1910	5310	3725,3265,4792,6714,5604,5894,2353,6772,5781,6464,2002,8976,7074,5295,998,7410,3716	JUN,HRAS,NFKBIA,SRC,MAP2K1,RAF1,FOS,STAT1,PTPN11,SHC1,ELK1,WASL,TIAM1,PIK3R1,CDC42,VAV2,JAK1
WP58	Monoamine GPCRs	0.16890092045571	-1.77844300547506	33	15	0.00785340314136126	1910	5310	3350,3355,155,1814,1128,148,154,1133,1812,3361,153,3274,1132,3356,1131	HTR1A,HTR1F,ADRB3,DRD3,CHRM1,ADRA1A,ADRB2,CHRM5,DRD1,HTR5A,ADRB1,HRH2,CHRM4,HTR2A,CHRM3
WP1971	Integrated Cancer Pathway	0.18040397269063	-1.7125566500294	46	20	0.0104712041884817	1910	5310	207,5925,7157,983,672,1026,4088,5728,571,466,581,572,1019,3716,4193,1027,4087,2956,4609,6772	AKT1,RB1,TP53,CDK1,BRCA1,CDKN1A,SMAD3,PTEN,BACH1,ATF1,BAX,BAD,CDK4,JAK1,MDM2,CDKN1B,SMAD2,MSH6,MYC,STAT1
WP500	Glycogen Metabolism	0.186162715401375	-1.68113417370979	36	16	0.00837696335078534	1910	5310	5516,5522,5518,2931,2997,5837,2632,7360,5529,5257,5525,5260,5236,5523,5834,5255	PPP2CB,PPP2R2C,PPP2R1A,GSK3A,GYS1,PYGM,GBE1,UGP2,PPP2R5E,PHKB,PPP2R5A,PHKG1,PGM1,PPP2R3A,PYGB,PHKA1
WP2012	miRs in Muscle Cell Differentiation	0.186162715401375	-1.68113417370979	36	16	0.00837696335078534	1910	5310	64100,4205,407006,5581,5567,23683,5588,5578,100271849,406904,2146,406989,5579,4208,407007,442890	ELSPBP1,MEF2A,MIR221,PRKCE,PRKACB,PRKD3,PRKCQ,PRKCA,MEF2B,MIR1-1,EZH2,MIR206,PRKCB,MEF2C,MIR222,MIR133B
WP2355	Corticotropin-releasing hormone signaling pathway	0.188203649337481	-1.67023066127772	93	38	0.0198952879581152	1910	5310	6770,2353,207,5604,1385,3576,1394,1584,1393,2776,100506742,5588,3726,3728,7099,2002,2767,1589,2781,2355,5579,5894,4929,2775,4792,3558,1499,2784,5578,31,2782,4790,3320,6667,3606,5908,2771,2697	STAR,FOS,AKT1,MAP2K1,CREB1,CXCL8,CRHR1,CYP11B1,CRHBP,GNAQ,CASP12,PRKCQ,JUNB,JUP,TLR4,ELK1,GNA11,CYP21A2,GNAZ,FOSL2,PRKCB,RAF1,NR4A2,GNAO1,NFKBIA,IL2,CTNNB1,GNB3,PRKCA,ACACA,GNB1,NFKB1,HSP90AA1,SP1,IL18,RAP1B,GNAI2,GJA1
WP3297	EV release from cardiac cells and their functional effects	0.188313868529674	-1.66964519478487	9	5	0.00261780104712042	1910	5310	5617,406913,7124,6387,406942	PRL,MIR126,TNF,CXCL12,MIR150
WP3300	Dual hijack model of Vif in HIV infection	0.188313868529674	-1.66964519478487	9	5	0.00261780104712042	1910	5310	60489,7314,6921,861,865	APOBEC3G,UBB,ELOC,RUNX1,CBFB
WP26	Signal Transduction of S1P Receptor	0.188373873205957	-1.66932660370721	26	12	0.00628272251308901	1910	5310	2771,5330,406974,6610,23236,2773,56848,5596,29127,10000,207,208	GNAI2,PLCB2,MIR197,SMPD2,PLCB1,GNAI3,SPHK2,MAPK4,RACGAP1,AKT3,AKT1,AKT2
WP313	Signaling of Hepatocyte Growth Factor Receptor	0.206375015866086	-1.57806029986197	34	15	0.00785340314136126	1910	5310	5781,1399,2002,5906,5908,5290,2549,6714,4233,5604,5894,2353,3725,3265,5728	PTPN11,CRKL,ELK1,RAP1A,RAP1B,PIK3CA,GAB1,SRC,MET,MAP2K1,RAF1,FOS,JUN,HRAS,PTEN
WP2267	Synaptic Vesicle Pathway	0.207226831129679	-1.57394128311131	52	22	0.0115183246073298	1910	5310	81539,6616,5864,140679,6804,2055,6812,6844,10814,6532,6855,160,477,291,594855,6507,1175,8775,10815,8224,1785,1173	SLC38A1,SNAP25,RAB3A,SLC32A1,STX1A,CLN8,STXBP1,VAMP2,CPLX2,SLC6A4,SYP,AP2A1,ATP1A2,SLC25A4,CPLX3,SLC1A3,AP2S1,NAPA,CPLX1,SYN3,DNM2,AP2M1
WP2805	RNA interference	0.216000296436042	-1.53247549890983	7	4	0.00209424083769634	1910	5310	29102,57510,54487,23405	DROSHA,XPO5,DGCR8,DICER1
WP1559	TFs Regulate miRNAs related to cardiac hypertrophy	0.234319736330382	-1.45106870171772	12	6	0.0031413612565445	1910	5310	208,207,442890,406904,50804,4790	AKT2,AKT1,MIR133B,MIR1-1,MYEF2,NFKB1
WP100	Glutathione metabolism	0.237103415266293	-1.43925888168599	22	10	0.00523560209424084	1910	5310	2952,2946,3417,2729,2938,2877,2876,2878,2879,2539	GSTT1,GSTM2,IDH1,GCLC,GSTA1,GPX2,GPX1,GPX3,GPX4,G6PD
WP3874	Canonical and Non-Canonical TGF-B signaling	0.238308789929988	-1.43418800957371	17	8	0.00418848167539267	1910	5310	4088,4087,657,659,4089,7048,26585,649	SMAD3,SMAD2,BMPR1A,BMPR2,SMAD4,TGFBR2,GREM1,BMP1
WP78	TCA Cycle	0.238308789929988	-1.43418800957371	17	8	0.00418848167539267	1910	5310	3420,6390,6391,50,3418,1743,3419,8801	IDH3B,SDHB,SDHC,ACO2,IDH2,DLST,IDH3A,SUCLG2
WP2916	Interactome of polycomb repressive complex 2 (PRC2)	0.238308789929988	-1.43418800957371	17	8	0.00418848167539267	1910	5310	8726,2145,23087,9967,11329,2146,5931,5928	EED,EZH1,TRIM35,THRAP3,STK38,EZH2,RBBP7,RBBP4
WP3596	miR-517 relationship with ARCN1 and USP1	0.250333473480805	-1.38496135604284	5	3	0.00157068062827225	1910	5310	372,3397,1026	ARCN1,ID1,CDKN1A
WP688	Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs)	0.250333473480805	-1.38496135604284	5	3	0.00157068062827225	1910	5310	2327,2328,2326	FMO2,FMO3,FMO1
WP2870	Extracellular vesicle-mediated signaling in recipient cells	0.254201334691831	-1.36962866968262	30	13	0.00680628272251309	1910	5310	1499,8842,4087,7043,4089,207,7042,7048,5894,4233,4088,3265,3845	CTNNB1,PROM1,SMAD2,TGFB3,SMAD4,AKT1,TGFB2,TGFBR2,RAF1,MET,SMAD3,HRAS,KRAS
WP1422	Sphingolipid Metabolism	0.266971602769975	-1.32061298290492	20	9	0.00471204188481675	1910	5310	64781,9331,2531,56848,9514,29956,57515,166929,253782	CERK,B4GALT6,KDSR,SPHK2,GAL3ST1,CERS2,SERINC1,SGMS2,CERS6
WP289	Myometrial Relaxation and Contraction Pathways	0.267087086051155	-1.32018050877652	158	61	0.0319371727748691	1910	5310	7529,2551,3569,59345,9446,466,2776,5021,10268,5588,8490,2787,6546,1902,3487,7532,5570,54331,3725,5142,3553,2553,5996,2782,468,5569,10287,5581,6001,6667,2697,59,2353,11142,1385,51764,818,2785,122042,55970,1394,60,9628,467,108,5997,5579,109,7534,57007,2791,7533,2788,10488,2784,784,2810,5578,4790,3486,5567	YWHAB,GABPA,IL6,GNB4,GSTO1,ATF1,GNAQ,OXTR,RAMP3,PRKCQ,RGS5,GNG5,SLC8A1,LPAR1,IGFBP4,YWHAG,PKIB,GNG2,JUN,PDE4B,IL1B,GABPB1,RGS1,GNB1,ATF4,PKIA,RGS19,PRKCE,RGS10,SP1,GJA1,ACTA2,FOS,PKIG,CREB1,GNG13,CAMK2G,GNG3,RXFP2,GNG12,CRHR1,ACTB,RGS6,ATF3,ADCY2,RGS2,PRKCB,ADCY3,YWHAZ,ACKR3,GNG11,YWHAH,GNG7,CREB3,GNB3,CACNB3,SFN,PRKCA,NFKB1,IGFBP3,PRKACB
WP704	Methylation Pathways	0.26999390684834	-1.30935588746678	10	5	0.00261780104712042	1910	5310	27430,3176,11185,4144,1312	MAT2B,HNMT,INMT,MAT2A,COMT
WP3	Transcriptional activation by NRF2	0.271078532082762	-1.30534671379912	15	7	0.00366492146596859	1910	5310	23657,2729,5290,5578,2939,4780,1728	SLC7A11,GCLC,PIK3CA,PRKCA,GSTA2,NFE2L2,NQO1
WP1544	MicroRNAs in cardiomyocyte hypertrophy	0.277112195641492	-1.28333281638378	102	40	0.0209424083769634	1910	5310	5330,5290,407034,1499,7124,9020,1154,4790,10454,3480,208,1022,5296,5294,5579,5596,5894,10014,406990,5295,1025,3551,406961,406932,407010,8503,5530,4040,406920,50804,3572,207,9475,442890,6093,8893,3479,5604,5606,5608	PLCB2,PIK3CA,MIR30E,CTNNB1,TNF,MAP3K14,CISH,NFKB1,TAB1,IGF1R,AKT2,CDK7,PIK3R2,PIK3CG,PRKCB,MAPK4,RAF1,HDAC5,MIR208A,PIK3R1,CDK9,IKBKB,MIR185,MIR140,MIR23A,PIK3R3,PPP3CA,LRP6,MIR130B,MYEF2,IL6ST,AKT1,ROCK2,MIR133B,ROCK1,EIF2B5,IGF1,MAP2K1,MAP2K3,MAP2K6
WP231	TNF alpha Signaling Pathway	0.277891474308333	-1.28052462169553	94	37	0.0193717277486911	1910	5310	3320,4215,7185,7128,10010,7124,4793,9020,4790,56957,3265,29110,4792,10454,3725,572,1387,2752,7295,5894,1457,329,3551,6500,7133,6610,23291,7186,581,3845,6347,207,23118,5606,5608,598,3569	HSP90AA1,MAP3K3,TRAF1,TNFAIP3,TANK,TNF,NFKBIB,MAP3K14,NFKB1,OTUD7B,HRAS,TBK1,NFKBIA,TAB1,JUN,BAD,CREBBP,GLUL,TXN,RAF1,CSNK2A1,BIRC2,IKBKB,SKP1,TNFRSF1B,SMPD2,FBXW11,TRAF2,BAX,KRAS,CCL2,AKT1,TAB2,MAP2K3,MAP2K6,BCL2L1,IL6
WP474	Endochondral Ossification	0.288070132467563	-1.24455131297891	65	26	0.0136125654450262	1910	5310	3479,4256,9510,3157,207,5744,7422,2260,54407,2688,249,6772,51719,657,7078,4208,6696,579,7042,3480,6662,4318,2690,871,50515,2487	IGF1,MGP,ADAMTS1,HMGCS1,AKT1,PTHLH,VEGFA,FGFR1,SLC38A2,GH1,ALPL,STAT1,CAB39,BMPR1A,TIMP3,MEF2C,SPP1,NKX3-2,TGFB2,IGF1R,SOX9,MMP9,GHR,SERPINH1,CHST11,FRZB
WP3612	Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling	0.292007667439579	-1.23097521870388	23	10	0.00523560209424084	1910	5310	2729,2052,3725,140809,1728,2353,9429,2950,1244,4780	GCLC,EPHX1,JUN,SRXN1,NQO1,FOS,ABCG2,GSTP1,ABCC2,NFE2L2
WP3408	Evolocumab Mechanism	0.295035005384137	-1.22066126736302	3	2	0.00104712041884817	1910	5310	255738,3949	PCSK9,LDLR
WP2846	Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation	0.295035005384137	-1.22066126736302	3	2	0.00104712041884817	1910	5310	255738,3949	PCSK9,LDLR
WP304	Kit receptor signaling pathway	0.29892495116216	-1.20756273655474	60	24	0.012565445026178	1910	5310	2887,5894,6714,5579,5296,3717,867,6591,572,3265,5578,2033,5781,5604,207,2353,3815,3726,1399,6464,6772,4286,5295,6776	GRB10,RAF1,SRC,PRKCB,PIK3R2,JAK2,CBL,SNAI2,BAD,HRAS,PRKCA,EP300,PTPN11,MAP2K1,AKT1,FOS,KIT,JUNB,CRKL,SHC1,STAT1,MITF,PIK3R1,STAT5A
WP3680	Association Between Physico-Chemical Features and Toxicity Associated Pathways	0.299095937905737	-1.20699089449584	68	27	0.0141361256544503	1910	5310	7114,2876,23002,4747,6464,7976,2890,6647,4690,4609,2002,6776,5604,207,9475,1027,1499,8323,5894,1026,6714,5294,867,8322,3725,10097,8536	TMSB4X,GPX1,DAAM1,NEFL,SHC1,FZD3,GRIA1,SOD1,NCK1,MYC,ELK1,STAT5A,MAP2K1,AKT1,ROCK2,CDKN1B,CTNNB1,FZD6,RAF1,CDKN1A,SRC,PIK3CG,CBL,FZD4,JUN,ACTR2,CAMK1
WP35	G Protein Signaling Pathways	0.305264196601119	-1.18657765896102	95	37	0.0193717277486911	1910	5310	2785,8165,5530,3760,3845,55970,2773,5151,51764,108,2790,2781,2767,2793,2776,5588,2775,3265,109,9590,5142,2791,2787,5579,23683,5581,5567,2771,2788,9630,5153,2784,5136,5150,2782,406974,5578	GNG3,AKAP1,PPP3CA,KCNJ3,KRAS,GNG12,GNAI3,PDE8A,GNG13,ADCY2,GNG10,GNAZ,GNA11,GNGT2,GNAQ,PRKCQ,GNAO1,HRAS,ADCY3,AKAP12,PDE4B,GNG11,GNG5,PRKCB,PRKD3,PRKCE,PRKACB,GNAI2,GNG7,GNA14,PDE1B,GNB3,PDE1A,PDE7A,GNB1,MIR197,PRKCA
WP2203	Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway	0.309655702538871	-1.17229423568861	47	19	0.00994764397905759	1910	5310	3569,5604,6714,3559,207,3717,3576,4792,7525,4790,1154,6356,3716,5781,6772,5290,4609,6776,6778	IL6,MAP2K1,SRC,IL2RA,AKT1,JAK2,CXCL8,NFKBIA,YES1,NFKB1,CISH,CCL11,JAK1,PTPN11,STAT1,PIK3CA,MYC,STAT5A,STAT6
WP1991	SRF and miRs in Smooth Muscle Differentiation and Proliferation	0.310061501608967	-1.1709846088931	13	6	0.0031413612565445	1910	5310	4208,4205,100271849,406937,2002,9314	MEF2C,MEF2A,MEF2B,MIR145,ELK1,KLF4
WP2272	Pathogenic Escherichia coli infection	0.310573137792373	-1.16933585690014	55	22	0.0115183246073298	1910	5310	10109,23643,929,5578,9076,7846,203068,1499,3059,7534,2017,7100,10094,10383,4690,8976,7099,998,60,10376,9475,6093	ARPC2,LY96,CD14,PRKCA,CLDN1,TUBA1A,TUBB,CTNNB1,HCLS1,YWHAZ,CTTN,TLR5,ARPC3,TUBB4B,NCK1,WASL,TLR4,CDC42,ACTB,TUBA1B,ROCK2,ROCK1
WP581	EPO Receptor Signaling	0.314185484817354	-1.15777175149906	26	11	0.00575916230366492	1910	5310	5894,5604,6714,5294,3717,207,6464,2056,6772,6776,1154	RAF1,MAP2K1,SRC,PIK3CG,JAK2,AKT1,SHC1,EPO,STAT1,STAT5A,CISH
WP1604	Codeine and Morphine Metabolism	0.314519384187609	-1.15670956980424	8	4	0.00209424083769634	1910	5310	54658,1244,5243,1565	UGT1A1,ABCC2,ABCB1,CYP2D6
WP237	Glucocorticoid & Mineralcorticoid Metabolism	0.314519384187609	-1.15670956980424	8	4	0.00209424083769634	1910	5310	1586,1585,3290,1589	CYP17A1,CYP11B2,HSD11B1,CYP21A2
WP400	p38 MAPK Signaling Pathway	0.319977261747136	-1.13950534275324	34	14	0.00732984293193717	1910	5310	8550,3265,7186,1649,5608,1385,7042,3315,6772,6464,2002,4609,4149,998	MAPKAPK5,HRAS,TRAF2,DDIT3,MAP2K6,CREB1,TGFB2,HSPB1,STAT1,SHC1,ELK1,MYC,MAX,CDC42
WP2636	Common Pathways Underlying Drug Addiction	0.322470493092687	-1.13174364121841	42	17	0.00890052356020942	1910	5310	2891,5502,5579,1385,5604,5894,5501,2890,5567,5906,5908,5500,5578,1812,60,2705,2911	GRIA2,PPP1R1A,PRKCB,CREB1,MAP2K1,RAF1,PPP1CC,GRIA1,PRKACB,RAP1A,RAP1B,PPP1CB,PRKCA,DRD1,ACTB,GJB1,GRM1
WP707	DNA Damage Response	0.332342641089547	-1.10158879079009	69	27	0.0141361256544503	1910	5310	1385,672,983,896,6118,5925,7157,581,1021,4193,5810,1019,595,5366,4609,3014,1026,891,4683,4616,5371,1647,355,1027,2810,10912,1020	CREB1,BRCA1,CDK1,CCND3,RPA2,RB1,TP53,BAX,CDK6,MDM2,RAD1,CDK4,CCND1,PMAIP1,MYC,H2AX,CDKN1A,CCNB1,NBN,GADD45B,PML,GADD45A,FAS,CDKN1B,SFN,GADD45G,CDK5
WP3613	Photodynamic therapy-induced unfolded protein response	0.334064841253654	-1.09642016935731	29	12	0.00628272251308901	1910	5310	5611,4189,7184,1649,4780,10130,7494,9695,467,811,468,3309	DNAJC3,DNAJB9,HSP90B1,DDIT3,NFE2L2,PDIA6,XBP1,EDEM1,ATF3,CALR,ATF4,HSPA5
WP3865	RIG-I-like Receptor Signaling	0.334369541326932	-1.09550848646869	61	24	0.012565445026178	1910	5310	3661,23586,56832,7189,3551,6387,57506,5602,3665,7186,3576,10010,4793,7124,4790,64135,80143,64343,3627,4792,29110,9636,3456,3458	IRF3,RIGI,IFNK,TRAF6,IKBKB,CXCL12,MAVS,MAPK10,IRF7,TRAF2,CXCL8,TANK,NFKBIB,TNF,NFKB1,IFIH1,SIKE1,AZI2,CXCL10,NFKBIA,TBK1,ISG15,IFNB1,IFNG
WP3529	Zinc homeostasis	0.336505071323296	-1.08914205921361	37	15	0.00785340314136126	1910	5310	4502,4499,64924,4504,7922,4501,4493,91252,148867,4489,57181,29985,55334,4500,4520	MT2A,MT1M,SLC30A5,MT3,SLC39A7,MT1X,MT1E,SLC39A13,SLC30A7,MT1A,SLC39A10,SLC39A3,SLC39A9,MT1L,MTF1
WP1946	Cori Cycle	0.341690295350086	-1.07385052134678	16	7	0.00366492146596859	1910	5310	3939,6513,5230,2875,2539,5223,2597	LDHA,SLC2A1,PGK1,GPT,G6PD,PGAM1,GAPDH
WP80	Nucleotide GPCRs	0.357196337699113	-1.02946968283439	11	5	0.00261780104712042	1910	5310	5030,10161,140,5028,134	P2RY4,LPAR6,ADORA3,P2RY1,ADORA1
WP179	Cell Cycle	0.358114835025907	-1.02690157578778	105	40	0.0209424083769634	1910	5310	9184,1026,891,4175,1874,1876,7534,7532,902,1647,1027,7533,4085,375,2033,890,140739,983,4173,5111,84515,7529,896,7157,9232,5925,4088,1021,10013,991,4193,5001,1019,8317,8841,4172,10459,23594,4089,10014	BUB3,CDKN1A,CCNB1,MCM6,E2F4,E2F6,YWHAZ,YWHAG,CCNH,GADD45A,CDKN1B,YWHAH,MAD2L1,ARF1,EP300,CCNA2,UBE2F,CDK1,MCM4,PCNA,MCM8,YWHAB,CCND3,TP53,PTTG1,RB1,SMAD3,CDK6,HDAC6,CDC20,MDM2,ORC5,CDK4,CDC7,HDAC3,MCM3,MAD2L2,ORC6,SMAD4,HDAC5
WP108	Selenium metabolism/Selenoproteins	0.359698681734074	-1.02248859319116	1	1	0.000523560209424084	1910	5310	9403	SELENOF
WP2911	miRNA targets in ECM and membrane receptors	0.366103592800574	-1.00483894519043	43	17	0.00890052356020942	1910	5310	407034,3913,693124,406933,6383,693174,406985,3693,554210,407030,442892,1278,1281,406901,406983,407014,407033	MIR30E,LAMB2,MIR532,MIR141,SDC2,MIR589,MIR200C,ITGB5,MIR429,MIR30B,MIR148B,COL1A2,COL3A1,MIR107,MIR200A,MIR25,MIR30D
WP2359	Parkin-Ubiquitin Proteasomal System pathway	0.366524505998808	-1.00368989495543	70	27	0.0141361256544503	1910	5310	5713,8573,5705,6477,5710,9861,7332,10383,51182,3312,6478,10376,10213,5718,5716,7327,3309,203068,5700,10273,7846,5709,5707,2861,5704,55294,5702	PSMD7,CASK,PSMC5,SIAH1,PSMD4,PSMD6,UBE2L3,TUBB4B,HSPA14,HSPA8,SIAH2,TUBA1B,PSMD14,PSMD12,PSMD10,UBE2G2,HSPA5,TUBB,PSMC1,STUB1,TUBA1A,PSMD3,PSMD1,GPR37,PSMC4,FBXW7,PSMC3
WP22	IL-9 Signaling Pathway	0.367731048903837	-1.00040345338089	19	8	0.00418848167539267	1910	5310	5295,6776,3561,6772,1025,5296,3716,5604	PIK3R1,STAT5A,IL2RG,STAT1,CDK9,PIK3R2,JAK1,MAP2K1
WP1992	TarBasePathway	0.367731048903837	-1.00040345338089	19	8	0.00418848167539267	1910	5310	3759,7114,9464,3479,406904,442890,2697,406905	KCNJ2,TMSB4X,HAND2,IGF1,MIR1-1,MIR133B,GJA1,MIR1-2
WP404	Nucleotide Metabolism	0.367731048903837	-1.00040345338089	19	8	0.00418848167539267	1910	5310	4946,4831,6303,159,6723,6240,5631,5423	OAZ1,NME2,SAT1,ADSS2,SRM,RRM1,PRPS1,POLB
WP61	Notch Signaling Pathway	0.370823650681079	-0.992028664473671	62	24	0.012565445026178	1910	5310	5296,3717,8819,1026,6714,171558,55294,51107,4790,3516,7088,2033,5664,207,23385,23493,6015,55851,5295,4609,6500,5663,595,4853	PIK3R2,JAK2,SAP30,CDKN1A,SRC,PTCRA,FBXW7,APH1A,NFKB1,RBPJ,TLE1,EP300,PSEN2,AKT1,NCSTN,HEY2,RING1,PSENEN,PIK3R1,MYC,SKP1,PSEN1,CCND1,NOTCH2
WP185	Integrin-mediated Cell Adhesion	0.378609351853916	-0.971250339365876	103	39	0.0204188481675393	1910	5310	857,5880,9475,207,6093,5602,5604,10000,5606,5608,56924,859,6464,407042,998,53358,823,858,3265,3693,5296,9815,3655,208,5596,5894,6714,5906,5908,3685,5062,6414,3673,824,3611,7410,7791,3696,1445	CAV1,RAC2,ROCK2,AKT1,ROCK1,MAPK10,MAP2K1,AKT3,MAP2K3,MAP2K6,PAK6,CAV3,SHC1,MIR34C,CDC42,SHC3,CAPN1,CAV2,HRAS,ITGB5,PIK3R2,GIT2,ITGA6,AKT2,MAPK4,RAF1,SRC,RAP1A,RAP1B,ITGAV,PAK2,SELENOP,ITGA2,CAPN2,ILK,VAV2,ZYX,ITGB8,CSK
WP3878	ATM Signaling Network in Development and Disease	0.379463750194568	-0.968996206617681	46	18	0.00942408376963351	1910	5310	4683,56254,6794,64421,3014,983,5932,9810,3930,2539,8493,1020,3315,8851,9656,4790,9025,5536	NBN,RNF20,STK11,DCLRE1C,H2AX,CDK1,RBBP8,RNF40,LBR,G6PD,PPM1D,CDK5,HSPB1,CDK5R1,MDC1,NFKB1,RNF8,PPP5C
WP710	DNA Damage Response (only ATM dependent)	0.381056453895113	-0.964807741878912	114	43	0.0225130890052356	1910	5310	6464,595,5366,5295,4089,4609,998,3146,7476,1856,4193,578,7472,356,581,5106,3845,5880,4088,6648,8503,10000,5602,207,896,7157,5529,5290,604,4790,6655,1027,3949,1499,572,7480,3725,5728,3265,1026,5294,5296,208	SHC1,CCND1,PMAIP1,PIK3R1,SMAD4,MYC,CDC42,HMGB1,WNT7A,DVL2,MDM2,BAK1,WNT2,FASLG,BAX,PCK2,KRAS,RAC2,SMAD3,SOD2,PIK3R3,AKT3,MAPK10,AKT1,CCND3,TP53,PPP2R5E,PIK3CA,BCL6,NFKB1,SOS2,CDKN1B,LDLR,CTNNB1,BAD,WNT10B,JUN,PTEN,HRAS,CDKN1A,PIK3CG,PIK3R2,AKT2
WP3853	ERK Pathway in Huntington's Disease	0.388900786227649	-0.944431016152001	14	6	0.0031413612565445	1910	5310	4915,2002,3265,2911,1385,5894	NTRK2,ELK1,HRAS,GRM1,CREB1,RAF1
WP3657	Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex	0.38983023561527	-0.942043927920252	22	9	0.00471204188481675	1910	5310	2033,1387,4089,5728,598,2120,4170,2553,2551	EP300,CREBBP,SMAD4,PTEN,BCL2L1,ETV6,MCL1,GABPB1,GABPA
WP410	Diurnally Regulated Genes with Circadian Orthologs	0.392016431084112	-0.936451524039229	49	19	0.00994764397905759	1910	5310	11335,2120,50486,694,51582,7360,5507,1407,687,5685,23118,2950,10787,3312,2947,6612,5516,8987,7341	CBX3,ETV6,G0S2,BTG1,AZIN1,UGP2,PPP1R3C,CRY1,KLF9,PSMA4,TAB2,GSTP1,NCKAP1,HSPA8,GSTM3,SUMO3,PPP2CB,STBD1,SUMO1
WP2363	Gastric Cancer Network 2	0.403323385271739	-0.908016593979159	33	13	0.00680628272251309	1910	5310	1499,51316,255488,55299,4609,5983,3930,5984,7157,92140,27101,6277,157769	CTNNB1,PLAC8,RNF144B,BRIX1,MYC,RFC3,LBR,RFC4,TP53,MTDH,CACYBP,S100A6,FAM91A1
WP24	Peptide GPCRs	0.410749519258567	-0.889771692464552	74	28	0.0146596858638743	1910	5310	1235,7852,1524,1909,4829,10663,2925,2833,7253,1230,553,1233,5021,6869,4987,4886,3577,6870,10396,680,729230,1234,1236,4986,4988,4887,1232,4889	CCR6,CXCR4,CX3CR1,EDNRA,NMBR,CXCR6,GRPR,CXCR3,TSHR,CCR1,AVPR1B,CCR4,OXTR,TACR1,OPRL1,NPY1R,CXCR1,TACR3,ATP8A1,BRS3,CCR2,CCR5,CCR7,OPRK1,OPRM1,NPY2R,CCR3,NPY5R
WP2289	Drug Induction of Bile Acid Pathway	0.414057349140989	-0.881750790255313	17	7	0.00366492146596859	1910	5310	8856,200931,1244,7421,1581,5243,9970	NR1I2,SLC51A,ABCC2,VDR,CYP7A1,ABCB1,NR1I3
WP368	Mitochondrial LC-Fatty Acid Beta-Oxidation	0.414057349140989	-0.881750790255313	17	7	0.00366492146596859	1910	5310	788,1376,3033,1962,2182,3030,35	SLC25A20,CPT2,HADH,EHHADH,ACSL4,HADHA,ACADS
WP585	Interferon type I signaling pathways	0.415048484293657	-0.879359935952218	55	21	0.0109947643979058	1910	5310	5296,9021,867,1975,1385,5606,5608,6773,1977,27250,10379,3454,3716,8554,5906,5295,8986,6776,1399,6772,5781	PIK3R2,SOCS3,CBL,EIF4B,CREB1,MAP2K3,MAP2K6,STAT2,EIF4E,PDCD4,IRF9,IFNAR1,JAK1,PIAS1,RAP1A,PIK3R1,RPS6KA4,STAT5A,CRKL,STAT1,PTPN11
WP3593	miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma	0.415483796716382	-0.878311662519527	9	4	0.00209424083769634	1910	5310	7422,406940,407035,7424	VEGFA,MIR148A,MIR31,VEGFC
WP3585	Cytosine methylation	0.415483796716382	-0.878311662519527	9	4	0.00209424083769634	1910	5310	53615,4204,3417,3418	MBD3,MECP2,IDH1,IDH2
WP2942	DDX1 as a regulatory component of the Drosha microprocessor	0.415483796716382	-0.878311662519527	9	4	0.00209424083769634	1910	5310	1653,54487,29102,4683	DDX1,DGCR8,DROSHA,NBN
WP560	TGF-beta Receptor Signaling	0.425669877328573	-0.854091168979184	58	22	0.0115183246073298	1910	5310	7124,9241,3716,1499,4790,4087,4089,6772,2033,2353,4090,7048,6696,7030,4093,4086,4088,2280,3265,3725,1387,3458	TNF,NOG,JAK1,CTNNB1,NFKB1,SMAD2,SMAD4,STAT1,EP300,FOS,SMAD5,TGFBR2,SPP1,TFE3,SMAD9,SMAD1,SMAD3,FKBP1A,HRAS,JUN,CREBBP,IFNG
WP732	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling	0.43490401299147	-0.832629932032132	20	8	0.00418848167539267	1910	5310	2005,5604,5894,2776,3356,3845,2002,3265	ELK4,MAP2K1,RAF1,GNAQ,HTR2A,KRAS,ELK1,HRAS
WP1533	Vitamin B12 Metabolism	0.445005119003457	-0.809669493503505	53	20	0.0104712041884817	1910	5310	5340,6347,3569,3383,4594,6648,3458,3039,3553,6352,7124,3949,213,12,2155,4790,3043,6649,6647,2147	PLG,CCL2,IL6,ICAM1,MMUT,SOD2,IFNG,HBA1,IL1B,CCL5,TNF,LDLR,ALB,SERPINA3,F7,NFKB1,HBB,SOD3,SOD1,F2
WP2491	Diclofenac Metabolic Pathway	0.454220460619591	-0.789172602726016	4	2	0.00104712041884817	1910	5310	1562,1558	CYP2C18,CYP2C8
WP897	Androgen receptor signaling pathway	0.454220460619591	-0.789172602726016	4	2	0.00104712041884817	1910	5310	1026,354	CDKN1A,KLK3
WP690	Polyol Pathway	0.454220460619591	-0.789172602726016	4	2	0.00104712041884817	1910	5310	6652,231	SORD,AKR1B1
WP1133	Androgen receptor signaling pathway	0.454220460619591	-0.789172602726016	4	2	0.00104712041884817	1910	5310	1026,354	CDKN1A,KLK3
WP521	Amino acid conjugation of benzoic acid	0.454220460619591	-0.789172602726016	4	2	0.00104712041884817	1910	5310	10249,55902	GLYAT,ACSS2
WP3302	eIF5A regulation in response to inhibition of the nuclear export system	0.454220460619591	-0.789172602726016	4	2	0.00104712041884817	1910	5310	7514,10642	XPO1,IGF2BP1
WP143	Fatty Acid Beta Oxidation	0.454918604596592	-0.787636767030591	34	13	0.00680628272251309	1910	5310	1375,3030,3033,1120,55902,788,2712,2820,38,35,2182,1376,1384	CPT1B,HADHA,HADH,CHKB,ACSS2,SLC25A20,GK2,GPD2,ACAT1,ACADS,ACSL4,CPT2,CRAT
WP481	Insulin Signaling	0.45804125399461	-0.780796024700352	161	59	0.0308900523560209	1910	5310	5781,5867,4215,5290,6655,5578,10211,375,4296,5967,53358,5770,3631,6812,5579,2887,208,6464,2002,382,5880,8503,6616,3636,9021,2353,10938,2997,5602,6513,8986,2549,9020,3480,7786,3725,1977,3265,57381,5728,5596,5894,6844,867,5296,5294,3551,5295,5588,8773,2931,7494,5604,5606,5608,6009,9882,207,1958	PTPN11,RAB4A,MAP3K3,PIK3CA,SOS2,PRKCA,FLOT1,ARF1,MAP3K11,REG1A,SHC3,PTPN1,INPP4A,STXBP1,PRKCB,GRB10,AKT2,SHC1,ELK1,ARF6,RAC2,PIK3R3,SNAP25,INPPL1,SOCS3,FOS,EHD1,GYS1,MAPK10,SLC2A1,RPS6KA4,GAB1,MAP3K14,IGF1R,MAP3K12,JUN,EIF4E,HRAS,RHOJ,PTEN,MAPK4,RAF1,VAMP2,CBL,PIK3R2,PIK3CG,IKBKB,PIK3R1,PRKCQ,SNAP23,GSK3A,XBP1,MAP2K1,MAP2K3,MAP2K6,RHEB,TBC1D4,AKT1,EGR1
WP197	Cholesterol Biosynthesis	0.46744895566397	-0.760465121960112	15	6	0.0031413612565445	1910	5310	4597,3157,50814,6309,2222,6307	MVD,HMGCS1,NSDHL,SC5D,FDFT1,MSMO1
WP422	MAPK Cascade	0.482128446013954	-0.729544714926364	29	11	0.00575916230366492	1910	5310	7786,3845,3725,4215,2002,3265,5604,5606,5894,5608,5602	MAP3K12,KRAS,JUN,MAP3K3,ELK1,HRAS,MAP2K1,MAP2K3,RAF1,MAP2K6,MAPK10
WP3879	4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression	0.485687346053668	-0.722190182978536	18	7	0.00366492146596859	1910	5310	4296,1977,5894,5606,5608,5604,207	MAP3K11,EIF4E,RAF1,MAP2K3,MAP2K6,MAP2K1,AKT1
WP2864	Apoptosis-related network due to altered Notch3 in ovarian cancer	0.486091719917995	-0.721357948776698	54	20	0.0104712041884817	1910	5310	9021,3070,207,1026,332,8878,3309,9616,7185,3329,7124,1728,27018,1027,8870,4790,1495,2729,3315,5062	SOCS3,HELLS,AKT1,CDKN1A,BIRC5,SQSTM1,HSPA5,RNF7,TRAF1,HSPD1,TNF,NQO1,BEX3,CDKN1B,IER3,NFKB1,CTNNA1,GCLC,HSPB1,PAK2
WP3595	mir-124 predicted interactions with cell cycle and differentiation	0.489962919593148	-0.713425565040607	7	3	0.00157068062827225	1910	5310	6794,58190,55437	STK11,CTDSP1,STRADB
WP134	Pentose Phosphate Pathway	0.489962919593148	-0.713425565040607	7	3	0.00157068062827225	1910	5310	2539,6120,22934	G6PD,RPE,RPIA
WP691	Tamoxifen metabolism	0.501090432170403	-0.690968690851902	21	8	0.00418848167539267	1910	5310	1558,1559,1565,1545,1577,1543,2328,2326	CYP2C8,CYP2C9,CYP2D6,CYP1B1,CYP3A5,CYP1A1,FMO3,FMO1
WP2507	Nanomaterial induced apoptosis	0.501090432170403	-0.690968690851902	21	8	0.00418848167539267	1910	5310	578,355,598,4170,356,27429,9131,581	BAK1,FAS,BCL2L1,MCL1,FASLG,HTRA2,AIFM1,BAX
WP534	Glycolysis and Gluconeogenesis	0.509388338026319	-0.674544610247488	49	18	0.00942408376963351	1910	5310	2023,3939,5162,5230,51660,5160,4190,2203,5223,2597,8789,3945,5091,6515,2026,92483,6513,1737	ENO1,LDHA,PDHB,PGK1,MPC1,PDHA1,MDH1,FBP1,PGAM1,GAPDH,FBP2,LDHB,PC,SLC2A3,ENO2,LDHAL6B,SLC2A1,DLAT
WP2113	Type III interferon signaling	0.512477056629935	-0.668499336523016	10	4	0.00209424083769634	1910	5310	6773,6772,10379,3716	STAT2,STAT1,IRF9,JAK1
WP1531	Vitamin D Metabolism	0.512477056629935	-0.668499336523016	10	4	0.00209424083769634	1910	5310	7421,1593,120227,1594	VDR,CYP27A1,CYP2R1,CYP27B1
WP1539	Angiogenesis	0.514470550676344	-0.664616964070538	24	9	0.00471204188481675	1910	5310	284,1387,7422,4086,5290,7078,6714,4318,207	ANGPT1,CREBBP,VEGFA,SMAD1,PIK3CA,TIMP3,SRC,MMP9,AKT1
WP2509	Nanoparticle triggered autophagic cell death	0.514470550676344	-0.664616964070538	24	9	0.00471204188481675	1910	5310	64422,10533,51100,406991,84557,81671,115201,8678,55054	ATG3,ATG7,SH3GLB1,MIR21,MAP1LC3A,VMP1,ATG4A,BECN1,ATG16L1
WP2029	Cell Differentiation - Index	0.516451094450454	-0.66077468135185	38	14	0.00732984293193717	1910	5310	442890,407007,574457,406942,4208,406957,406904,100271849,407046,10014,407006,406951,4205,406950	MIR133B,MIR222,MIR181D,MIR150,MEF2C,MIR181C,MIR1-1,MEF2B,MIR9-1,HDAC5,MIR221,MIR16-2,MEF2A,MIR16-1
WP1772	Apoptosis Modulation and Signaling	0.523018711793217	-0.648138037749926	94	34	0.0178010471204188	1910	5310	581,9131,27429,51651,8682,4170,2353,7157,598,1676,329,5366,7189,3551,356,7133,51155,578,4615,7850,4792,8743,3725,572,666,9531,8738,597,332,837,54472,4790,355,9020	BAX,AIFM1,HTRA2,PTRH2,PEA15,MCL1,FOS,TP53,BCL2L1,DFFA,BIRC2,PMAIP1,TRAF6,IKBKB,FASLG,TNFRSF1B,JPT1,BAK1,MYD88,IL1R2,NFKBIA,TNFSF10,JUN,BAD,BOK,BAG3,CRADD,BCL2A1,BIRC5,CASP4,TOLLIP,NFKB1,FAS,MAP3K14
WP3679	Cell-type Dependent Selectivity of CCK2R Signaling	0.529280236831572	-0.636237239127072	13	5	0.00261780104712042	1910	5310	2776,952,7220,23236,1268	GNAQ,CD38,TRPC1,PLCB1,CNR1
WP3871	Valproic acid pathway	0.529280236831572	-0.636237239127072	13	5	0.00261780104712042	1910	5310	1559,36,3030,3028,1962	CYP2C9,ACADSB,HADHA,HSD17B10,EHHADH
WP314	Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation	0.535193952594629	-0.625126069569345	44	16	0.00837696335078534	1910	5310	407042,7124,356,6709,60,355,3552,5062,4001,3315,5925,11124,7867,1676,4000,3725	MIR34C,TNF,FASLG,SPTAN1,ACTB,FAS,IL1A,PAK2,LMNB1,HSPB1,RB1,FAF1,MAPKAPK3,DFFA,LMNA,JUN
WP98	Prostaglandin Synthesis and Regulation	0.537024969046497	-0.621710688260947	30	11	0.00575916230366492	1910	5310	1909,5732,5617,5734,5737,6281,3290,5731,6277,5730,307	EDNRA,PTGER2,PRL,PTGER4,PTGFR,S100A10,HSD11B1,PTGER1,S100A6,PTGDS,ANXA4
WP236	Adipogenesis	0.542285250986567	-0.611963122653106	131	47	0.0246073298429319	1910	5310	3952,1649,1874,7480,7124,1499,5468,1592,26580,5925,9021,10269,3159,1385,1271,4692,5465,649,6695,6772,2688,6258,2303,1026,4208,4000,1647,4616,355,2487,6667,5008,56729,3569,3479,6773,4088,55847,5106,3572,9370,1959,6778,6424,6776,4282,4205	LEP,DDIT3,E2F4,WNT10B,TNF,CTNNB1,PPARG,CYP26A1,BSCL2,RB1,SOCS3,ZMPSTE24,HMGA1,CREB1,CNTFR,NDN,PPARA,BMP1,SPOCK1,STAT1,GH1,RXRG,FOXC2,CDKN1A,MEF2C,LMNA,GADD45A,GADD45B,FAS,FRZB,SP1,OSM,RETN,IL6,IGF1,STAT2,SMAD3,CISD1,PCK2,IL6ST,ADIPOQ,EGR2,STAT6,SFRP4,STAT5A,MIF,MEF2A
WP550	Biogenic Amine Synthesis	0.542904151851852	-0.610822490555579	16	6	0.0031413612565445	1910	5310	1312,43,438,15,1621,2572	COMT,ACHE,ASMT,AANAT,DBH,GAD2
WP12	Osteoclast Signaling	0.542904151851852	-0.610822490555579	16	6	0.0031413612565445	1910	5310	1513,6696,9550,3456,54,3454	CTSK,SPP1,ATP6V1G1,IFNB1,ACP5,IFNAR1
WP3676	BDNF-TrkB Signaling	0.546773318030605	-0.603720971901931	33	12	0.00628272251308901	1910	5310	2549,6464,1742,3265,4915,3845,9456,5294,207,6009,1385,5604	GAB1,SHC1,DLG4,HRAS,NTRK2,KRAS,HOMER1,PIK3CG,AKT1,RHEB,CREB1,MAP2K1
WP734	Serotonin Receptor 4/6/7 and NR3C Signaling	0.554495186052776	-0.589697153829443	19	7	0.00366492146596859	1910	5310	5604,1385,2005,1958,5906,466,2002	MAP2K1,CREB1,ELK4,EGR1,RAP1A,ATF1,ELK1
WP247	Small Ligand GPCRs	0.554495186052776	-0.589697153829443	19	7	0.00366492146596859	1910	5310	5731,5732,1902,5737,8698,1268,5734	PTGER1,PTGER2,LPAR1,PTGFR,S1PR4,CNR1,PTGER4
WP170	Nuclear Receptors	0.564088405983484	-0.572544291570127	39	14	0.00732984293193717	1910	5310	9970,5465,7421,5241,6258,2063,367,190,4929,7376,7101,8856,2100,5468	NR1I3,PPARA,VDR,PGR,RXRG,NR2F6,AR,NR0B1,NR4A2,NR1H2,NR2E1,NR1I2,ESR2,PPARG
WP357	Fatty Acid Biosynthesis	0.564667687345902	-0.571517884861541	22	8	0.00418848167539267	1910	5310	55862,10449,31,51102,2182,3033,55902,5091	ECHDC1,ACAA2,ACACA,MECR,ACSL4,HADH,ACSS2,PC
WP1424	Globo Sphingolipid Metabolism	0.564667687345902	-0.571517884861541	22	8	0.00418848167539267	1910	5310	6480,10690,6483,2590,256435,8706,2523,6482	ST6GAL1,FUT9,ST3GAL2,GALNT2,ST6GALNAC3,B3GALNT1,FUT1,ST3GAL1
WP2112	IL17 signaling pathway	0.589753703241972	-0.528050281372021	31	11	0.00575916230366492	1910	5310	3551,112744,6667,7189,9020,4790,10758,3716,207,4793,3717	IKBKB,IL17F,SP1,TRAF6,MAP3K14,NFKB1,TRAF3IP2,JAK1,AKT1,NFKBIB,JAK2
WP1273	Folic Acid Network	0.590057603915383	-0.527535113093351	2	1	0.000523560209424084	1910	5310	7295	TXN
WP2901	Gonadotropin-releasing hormone (GnRH) signaling	0.590057603915383	-0.527535113093351	2	1	0.000523560209424084	1910	5310	4323	MMP14
WP2366	Butyrate-induced histone acetylation	0.590057603915383	-0.527535113093351	2	1	0.000523560209424084	1910	5310	207	AKT1
WP1311	Folic Acid Network	0.590057603915383	-0.527535113093351	2	1	0.000523560209424084	1910	5310	7295	TXN
WP1438	Influenza A virus infection	0.590057603915383	-0.527535113093351	2	1	0.000523560209424084	1910	5310	407042	MIR34C
WP2943	Hypoxia-mediated EMT and Stemness	0.590057603915383	-0.527535113093351	2	1	0.000523560209424084	1910	5310	23405	DICER1
WP2542	Sulindac Metabolic Pathway	0.590145118714533	-0.527386808403601	5	2	0.00104712041884817	1910	5310	253827,1545	MSRB3,CYP1B1
WP2597	Secretion of Hydrochloric Acid in Parietal Cells	0.590145118714533	-0.527386808403601	5	2	0.00104712041884817	1910	5310	1128,3274	CHRM1,HRH2
WP311	Synthesis and Degradation of Ketone Bodies	0.590145118714533	-0.527386808403601	5	2	0.00104712041884817	1910	5310	38,5019	ACAT1,OXCT1
WP136	Phase I biotransformations, non P450	0.595229040830055	-0.51880900493637	8	3	0.00157068062827225	1910	5310	3988,2098,221223	LIPA,ESD,CES5A
WP1601	Fluoropyrimidine Activity	0.596875888994915	-0.516046078332688	34	12	0.00628272251308901	1910	5310	8836,5471,83549,10057,7157,7372,23583,7298,6240,2030,7371,9429	GGH,PPAT,UCK1,ABCC5,TP53,UMPS,SMUG1,TYMS,RRM1,SLC29A1,UCK2,ABCG2
WP673	ErbB Signaling Pathway	0.598927935503857	-0.512613996111193	54	19	0.00994764397905759	1910	5310	5578,1027,4193,1839,2549,6776,4609,2002,4690,595,7157,10000,5604,6714,1026,3265,3845,572,3725	PRKCA,CDKN1B,MDM2,HBEGF,GAB1,STAT5A,MYC,ELK1,NCK1,CCND1,TP53,AKT3,MAP2K1,SRC,CDKN1A,HRAS,KRAS,BAD,JUN
WP3414	Initiation of transcription and translation elongation at the HIV-1 LTR	0.603549805150851	-0.504926714673507	37	13	0.00680628272251309	1910	5310	8841,10614,2033,1025,6667,10014,4790,6829,6827,1387,4792,5535,5530	HDAC3,HEXIM1,EP300,CDK9,SP1,HDAC5,NFKB1,SUPT5H,SUPT4H1,CREBBP,NFKBIA,PPP3R2,PPP3CA
WP2436	Dopamine metabolism	0.607268820511151	-0.498783718560531	14	5	0.00261780104712042	1910	5310	5567,6647,5516,1728,1312	PRKACB,SOD1,PPP2CB,NQO1,COMT
WP2516	ATM Signaling Pathway	0.609841373084174	-0.494556399756422	40	14	0.00732984293193717	1910	5310	3725,4683,8738,4792,1647,1385,3014,1026,983,672,891,7157,9656,4193	JUN,NBN,CRADD,NFKBIA,GADD45A,CREB1,H2AX,CDKN1A,CDK1,BRCA1,CCNB1,TP53,MDC1,MDM2
WP2371	Parkinsons Disease Pathway	0.618888096150107	-0.479830804304316	83	29	0.0151832460732984	1910	5310	406994,27429,406890,7314,407017,406971,406951,406927,407041,7332,442915,6531,406952,407042,406899,406921,574031,406902,406982,2861,442906,100126316,407029,407034,574456,574506,100187716,494324,7327	MIR212,HTRA2,MIRLET7G,UBB,MIR26B,MIR195,MIR16-2,MIR136,MIR34B,UBE2L3,MIR370,SLC6A3,MIR17,MIR34C,MIR106A,MIR132,MIR363,MIR10A,MIR20A,GPR37,MIR338,MIR873,MIR30A,MIR30E,MIR497,MIR503,MIR1224,MIR375,UBE2G2
WP391	Mitochondrial Gene Expression	0.618890433083054	-0.479827028292872	20	7	0.00366492146596859	1910	5310	5530,6667,2551,2553,50804,1385,51106	PPP3CA,SP1,GABPA,GABPB1,MYEF2,CREB1,TFB1M
WP497	Urea cycle and metabolism of amino groups	0.618890433083054	-0.479827028292872	20	7	0.00366492146596859	1910	5310	6723,5831,2593,4953,4942,384,1152	SRM,PYCR1,GAMT,ODC1,OAT,ARG2,CKB
WP1591	Heart Development	0.621473263294588	-0.475662388595378	46	16	0.00837696335078534	1910	5310	659,7422,8553,23493,4086,7424,406937,2303,4208,9464,657,4089,5781,1499,2255,406904	BMPR2,VEGFA,BHLHE40,HEY2,SMAD1,VEGFC,MIR145,FOXC2,MEF2C,HAND2,BMPR1A,SMAD4,PTPN11,CTNNB1,FGF10,MIR1-1
WP399	Wnt Signaling Pathway and Pluripotency	0.627175370614011	-0.466529079508414	106	37	0.0193717277486911	1910	5310	1487,7157,896,5602,1454,5516,5518,4040,7472,1856,7476,5588,4609,5048,10009,6657,595,7976,8322,5579,29127,5522,1500,5460,1387,7480,3725,1499,3949,5523,5578,8323,4800,5581,5529,2033,27022	CTBP1,TP53,CCND3,MAPK10,CSNK1E,PPP2CB,PPP2R1A,LRP6,WNT2,DVL2,WNT7A,PRKCQ,MYC,PAFAH1B1,ZBTB33,SOX2,CCND1,FZD3,FZD4,PRKCB,RACGAP1,PPP2R2C,CTNND1,POU5F1,CREBBP,WNT10B,JUN,CTNNB1,LDLR,PPP2R3A,PRKCA,FZD6,NFYA,PRKCE,PPP2R5E,EP300,FOXD3
WP2875	Constitutive Androstane Receptor Pathway	0.639591035066528	-0.446926314589413	32	11	0.00575916230366492	1910	5310	1962,1559,9970,7266,5243,2939,1244,3320,6667,1577,54658	EHHADH,CYP2C9,NR1I3,DNAJC7,ABCB1,GSTA2,ABCC2,HSP90AA1,SP1,CYP3A5,UGT1A1
WP299	Nuclear Receptors in Lipid Metabolism and Toxicity	0.644296369600403	-0.439596457495037	35	12	0.00628272251308901	1910	5310	1594,5465,1592,693120,9970,1244,1559,8856,5468,5243,1581,7421	CYP27B1,PPARA,CYP26A1,MIR33B,NR1I3,ABCC2,CYP2C9,NR1I2,PPARG,ABCB1,CYP7A1,VDR
WP1982	Sterol Regulatory Element-Binding Proteins (SREBP) signalling	0.663530571817009	-0.410180349682055	73	25	0.0130890052356021	1910	5310	6396,7376,4597,5290,4800,6667,31,5468,3949,5564,693120,1024,51128,5571,51141,820,10484,4190,57678,2222,2931,1385,11236,3157,207	SEC13,NR1H2,MVD,PIK3CA,NFYA,SP1,ACACA,PPARG,LDLR,PRKAB1,MIR33B,CDK8,SAR1B,PRKAG1,INSIG2,CAMP,SEC23A,MDH1,GPAM,FDFT1,GSK3A,CREB1,RNF139,HMGCS1,AKT1
WP3413	NOTCH1 regulation of human endothelial cell calcification	0.676932666060608	-0.390183470306357	18	6	0.0031413612565445	1910	5310	813,249,6303,7422,1902,4256	CALU,ALPL,SAT1,VEGFA,LPAR1,MGP
WP3859	TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition	0.676932666060608	-0.390183470306357	18	6	0.0031413612565445	1910	5310	4087,4088,4089,3397,207,6591	SMAD2,SMAD3,SMAD4,ID1,AKT1,SNAI2
WP3664	Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds	0.676932666060608	-0.390183470306357	18	6	0.0031413612565445	1910	5310	1856,1499,8658,1452,6424,27122	DVL2,CTNNB1,TNKS,CSNK1A1,SFRP4,DKK3
WP1602	Nicotine Activity on Dopaminergic Neurons	0.67779043354679	-0.388917133885199	21	7	0.00366492146596859	1910	5310	1814,2782,84152,108,54331,1020,1141	DRD3,GNB1,PPP1R1B,ADCY2,GNG2,CDK5,CHRNB2
WP2533	Glycerophospholipid Biosynthetic Pathway	0.67779043354679	-0.388917133885199	21	7	0.00366492146596859	1910	5310	9489,8394,1120,9791,8443,114971,10423	PGS1,PIP5K1A,CHKB,PTDSS1,GNPAT,PTPMT1,CDIPT
WP106	Alanine and aspartate metabolism	0.67933067470311	-0.386647267462414	12	4	0.00209424083769634	1910	5310	2572,5091,2875,443	GAD2,PC,GPT,ASPA
WP3672	LncRNA-mediated mechanisms of therapeutic resistance	0.67933067470311	-0.386647267462414	12	4	0.00209424083769634	1910	5310	598,1026,5243,7157	BCL2L1,CDKN1A,ABCB1,TP53
WP3584	MECP2 and Associated Rett Syndrome	0.68063998274555	-0.384721772320597	62	21	0.0109947643979058	1910	5310	2894,4204,1267,4208,1385,207,7337,2248,4986,2530,2146,25942,1465,604,9315,3185,4354,2890,2593,6667,6750	GRID1,MECP2,CNP,MEF2C,CREB1,AKT1,UBE3A,FGF3,OPRK1,FUT8,EZH2,SIN3A,CSRP1,BCL6,NREP,HNRNPF,MPP1,GRIA1,GAMT,SP1,SST
WP3298	Melatonin metabolism and effects	0.688568594753366	-0.373140336504684	36	12	0.00628272251308901	1910	5310	406938,1545,406913,1565,1454,1543,153,5578,43,4790,7189,1407	MIR146A,CYP1B1,MIR126,CYP2D6,CSNK1E,CYP1A1,ADRB1,PRKCA,ACHE,NFKB1,TRAF6,CRY1
WP1600	Nicotine Metabolism	0.698942494672564	-0.358186808125995	6	2	0.00104712041884817	1910	5310	2328,316	FMO3,AOX1
WP3891	Benzene metabolism	0.698942494672564	-0.358186808125995	6	2	0.00104712041884817	1910	5310	2052,1728	EPHX1,NQO1
WP1528	Physiological and Pathological Hypertrophy  of the Heart	0.728992581541298	-0.316091723237468	25	8	0.00418848167539267	1910	5310	2353,5606,5579,5581,5530,3572,3725,50804	FOS,MAP2K3,PRKCB,PRKCE,PPP3CA,IL6ST,JUN,MYEF2
WP2895	Differentiation of white and brown adipocyte	0.728992581541298	-0.316091723237468	25	8	0.00418848167539267	1910	5310	9370,4086,1054,4093,5468,3952,4090,51316	ADIPOQ,SMAD1,CEBPG,SMAD9,PPARG,LEP,SMAD5,PLAC8
WP1471	Target Of Rapamycin (TOR) Signaling	0.729377613774063	-0.315563692367188	37	12	0.00628272251308901	1910	5310	5578,998,10325,115265,5571,6009,207,54541,5564,2280,79899,10670	PRKCA,CDC42,RRAGB,DDIT4L,PRKAG1,RHEB,AKT1,DDIT4,PRKAB1,FKBP1A,PRR5L,RRAGA
WP3599	Transcription factor regulation in adipogenesis	0.730581048441448	-0.31391510467619	22	7	0.00366492146596859	1910	5310	5106,9370,1385,3569,5468,3952,7124	PCK2,ADIPOQ,CREB1,IL6,PPARG,LEP,TNF
WP465	Tryptophan metabolism	0.733013275032712	-0.310591466710078	46	15	0.00785340314136126	1910	5310	316,11185,15,38,1562,4193,3033,3620,3028,66002,1545,1572,438,1543,7337	AOX1,INMT,AANAT,ACAT1,CYP2C18,MDM2,HADH,IDO1,HSD17B10,CYP4F12,CYP1B1,CYP2F1,ASMT,CYP1A1,UBE3A
WP3287	Overview of nanoparticle effects	0.733442272211738	-0.31000638632074	19	6	0.0031413612565445	1910	5310	3569,10000,7124,896,581,3576	IL6,AKT3,TNF,CCND3,BAX,CXCL8
WP697	Estrogen metabolism	0.733442272211738	-0.31000638632074	19	6	0.0031413612565445	1910	5310	54658,1543,1312,2938,1545,1728	UGT1A1,CYP1A1,COMT,GSTA1,CYP1B1,NQO1
WP53	ID signaling pathway	0.738212662529625	-0.30352333528271	16	5	0.00261780104712042	1910	5310	2002,3397,5925,2005,2004	ELK1,ID1,RB1,ELK4,ELK3
WP306	Focal Adhesion	0.758713935144837	-0.276130469672424	195	66	0.0345549738219895	1910	5310	53358,1278,3693,208,3655,6714,6696,4637,5906,5908,5290,3685,6414,1499,3611,3696,7450,53918,857,7424,5880,55359,9475,6093,4233,10000,2002,56924,6464,60,998,3265,823,858,5728,388,3480,572,3725,5296,5294,394,1281,5596,5894,4659,3913,3673,10420,5062,7791,7059,7422,7143,2268,207,896,3479,5604,5608,5606,5295,329,859,57144,595	SHC3,COL1A2,ITGB5,AKT2,ITGA6,SRC,SPP1,MYL6,RAP1A,RAP1B,PIK3CA,ITGAV,SELENOP,CTNNB1,ILK,ITGB8,VWF,PELO,CAV1,VEGFC,RAC2,STYK1,ROCK2,ROCK1,MET,AKT3,ELK1,PAK6,SHC1,ACTB,CDC42,HRAS,CAPN1,CAV2,PTEN,RHOB,IGF1R,BAD,JUN,PIK3R2,PIK3CG,ARHGAP5,COL3A1,MAPK4,RAF1,PPP1R12A,LAMB2,ITGA2,TESK2,PAK2,ZYX,THBS3,VEGFA,TNR,FGR,AKT1,CCND3,IGF1,MAP2K1,MAP2K6,MAP2K3,PIK3R1,BIRC2,CAV3,PAK5,CCND1
WP496	Steroid Biosynthesis	0.759083637004673	-0.275643313975339	10	3	0.00157068062827225	1910	5310	3292,3293,1586	HSD17B1,HSD17B3,CYP17A1
WP51	Regulation of Actin Cytoskeleton	0.759614537118785	-0.274944162366699	149	50	0.0261780104712042	1910	5310	4478,2252,8394,929,1133,1445,6655,2257,5290,1072,79837,9475,6093,1131,8823,8503,55970,5880,22800,60,2260,998,56924,22808,5296,5294,10787,1073,5596,5894,2258,1132,2246,2248,4659,5062,5604,54961,3845,2255,9459,8822,7114,1128,2147,5295,26999,27006,8074,57144	MSN,FGF7,PIP5K1A,CD14,CHRM5,CSK,SOS2,FGF12,PIK3CA,CFL1,PIP4K2C,ROCK2,ROCK1,CHRM3,FGF16,PIK3R3,GNG12,RAC2,RRAS2,ACTB,FGFR1,CDC42,PAK6,MRAS,PIK3R2,PIK3CG,NCKAP1,CFL2,MAPK4,RAF1,FGF13,CHRM4,FGF1,FGF3,PPP1R12A,PAK2,MAP2K1,SSH3,KRAS,FGF10,ARHGEF6,FGF17,TMSB4X,CHRM1,F2,PIK3R1,CYFIP2,FGF22,FGF23,PAK5
WP716	Vitamin A and Carotenoid Metabolism	0.766219755544233	-0.266286263252327	44	14	0.00732984293193717	1910	5310	6258,220,9249,145226,9227,124,195814,29881,5948,948,1592,1382,54884,157506	RXRG,ALDH1A3,DHRS3,RDH12,LRAT,ADH1A,SDR16C5,NPC1L1,RBP2,CD36,CYP26A1,CRABP2,RETSAT,RDH10
WP244	Alpha 6 Beta 4 signaling pathway	0.767274772817016	-0.264910298200317	35	11	0.00575916230366492	1910	5310	5578,6714,3655,207,5296,6464,5781,3913,2549,5295,3265	PRKCA,SRC,ITGA6,AKT1,PIK3R2,SHC1,PTPN11,LAMB2,GAB1,PIK3R1,HRAS
WP34	Ovarian Infertility Genes	0.768509958886574	-0.263301757223985	32	10	0.00523560209424084	1910	5310	4088,658,1027,2100,3623,7421,5732,1019,1958,5241	SMAD3,BMPR1B,CDKN1B,ESR2,INHA,VDR,PTGER2,CDK4,EGR1,PGR
WP2878	PPAR Alpha Pathway	0.773147180521361	-0.257285846809426	26	8	0.00418848167539267	1910	5310	595,5465,1376,4609,983,1962,1019,1581	CCND1,PPARA,CPT2,MYC,CDK1,EHHADH,CDK4,CYP7A1
WP699	Aflatoxin B1 metabolism	0.782534324700474	-0.245217492097973	7	2	0.00104712041884817	1910	5310	8574,2052	AKR7A2,EPHX1
WP1995	Effects of Nitric Oxide	0.782534324700474	-0.245217492097973	7	2	0.00104712041884817	1910	5310	3039,316	HBA1,AOX1
WP438	Non-homologous end joining	0.782534324700474	-0.245217492097973	7	2	0.00104712041884817	1910	5310	7520,79840	XRCC5,NHEJ1
WP3924	Hfe effect on hepcidin production	0.782534324700474	-0.245217492097973	7	2	0.00104712041884817	1910	5310	3397,3077	ID1,HFE
WP528	Acetylcholine Synthesis	0.782534324700474	-0.245217492097973	7	2	0.00104712041884817	1910	5310	5160,43	PDHA1,ACHE
WP3678	Amplification and Expansion of Oncogenic Pathways as Metastatic Traits	0.790307844390463	-0.235332732981593	17	5	0.00261780104712042	1910	5310	7852,6714,5294,7422,7472	CXCR4,SRC,PIK3CG,VEGFA,WNT2
WP2848	Differentiation Pathway	0.796974263473916	-0.226932892464986	48	15	0.00785340314136126	1910	5310	7422,3815,2246,22943,7018,3569,3479,4909,3577,7043,2056,9241,2255,7472,3562	VEGFA,KIT,FGF1,DKK1,TF,IL6,IGF1,NTF4,CXCR1,TGFB3,EPO,NOG,FGF10,WNT2,IL3
WP229	Irinotecan Pathway	0.801520133273896	-0.221245187754699	14	4	0.00209424083769634	1910	5310	1244,54658,1577,9429	ABCC2,UGT1A1,CYP3A5,ABCG2
WP2197	Endothelin Pathways	0.804383900321962	-0.217678635801634	33	10	0.00523560209424084	1910	5310	148,4852,5604,5578,5894,51764,1909,23236,153,4886	ADRA1A,NPY,MAP2K1,PRKCA,RAF1,GNG13,EDNRA,PLCB1,ADRB1,NPY1R
WP129	Matrix Metalloproteinases	0.807618539658237	-0.213665436320773	30	9	0.00471204188481675	1910	5310	118856,7079,7076,7078,4323,79148,7124,4318,9313	MMP21,TIMP4,TIMP1,TIMP3,MMP14,MMP28,TNF,MMP9,MMP20
WP2858	Ectoderm Differentiation	0.807878902754557	-0.213343104521616	143	47	0.0246073298429319	1910	5310	56963,460,6386,494323,6785,657,4609,157807,345557,4771,407042,6781,7704,57621,60401,54521,152789,1496,8322,9079,29970,8345,57462,6016,1499,54207,10013,10486,6347,5010,1487,4089,7903,5080,22871,6657,8675,8835,3728,55843,5236,1006,4204,57154,51762,5269,5150	RGMA,ASTN1,SDCBP,MIR361,ELOVL4,BMPR1A,MYC,CLVS1,PLCXD3,NF2,MIR34C,STC1,ZBTB16,ZBTB2,EDA2R,WDR44,JAKMIP1,CTNNA2,FZD4,LDB2,SCHIP1,H2BC9,MYORG,RIT1,CTNNB1,KCNK10,HDAC6,CAP2,CCL2,CLDN11,CTBP1,SMAD4,ST8SIA4,PAX6,NLGN1,SOX2,STX16,SOCS2,JUP,ARHGAP15,PGM1,CDH8,MECP2,SMURF1,RAB8B,SERPINB6,PDE7A
WP428	Wnt Signaling Pathway	0.82135093117319	-0.196804817284985	70	22	0.0115183246073298	1910	5310	5529,7976,595,6424,8323,5581,4609,5048,7476,1856,5588,5578,7472,1499,3949,4040,7480,3725,1454,5579,896,5602	PPP2R5E,FZD3,CCND1,SFRP4,FZD6,PRKCE,MYC,PAFAH1B1,WNT7A,DVL2,PRKCQ,PRKCA,WNT2,CTNNB1,LDLR,LRP6,WNT10B,JUN,CSNK1E,PRKCB,CCND3,MAPK10
WP2253	Pilocytic astrocytoma	0.832018384053286	-0.183900742187155	4	1	0.000523560209424084	1910	5310	5781	PTPN11
WP3633	Caffeine and Theobromine metabolism	0.832018384053286	-0.183900742187155	4	1	0.000523560209424084	1910	5310	10	NAT2
WP1941	Peroxisomal beta-oxidation of tetracosanoyl-CoA	0.832018384053286	-0.183900742187155	4	1	0.000523560209424084	1910	5310	51	ACOX1
WP1589	Folate-Alcohol and Cancer Pathway	0.844969419315199	-0.168454842439371	8	2	0.00104712041884817	1910	5310	1385,10840	CREB1,ALDH1L1
WP3635	Insulin signalling in human adipocytes (diabetic condition)	0.844969419315199	-0.168454842439371	8	2	0.00104712041884817	1910	5310	208,9882	AKT2,TBC1D4
WP3634	Insulin signalling in human adipocytes (normal condition)	0.844969419315199	-0.168454842439371	8	2	0.00104712041884817	1910	5310	9882,208	TBC1D4,AKT2
WP3655	Hypothetical Craniofacial Development Pathway	0.844969419315199	-0.168454842439371	8	2	0.00104712041884817	1910	5310	3664,7043	IRF6,TGFB3
WP206	Fatty Acid Omega Oxidation	0.846735180677106	-0.166367288852104	15	4	0.00209424083769634	1910	5310	125,1543,1565,124	ADH1B,CYP1A1,CYP2D6,ADH1A
WP363	Wnt Signaling Pathway Netpath	0.847596456979935	-0.165350632658156	53	16	0.00837696335078534	1910	5310	1454,2931,1021,607,4040,1452,1487,207,5579,4609,595,2697,1499,1856,5468,5578	CSNK1E,GSK3A,CDK6,BCL9,LRP6,CSNK1A1,CTBP1,AKT1,PRKCB,MYC,CCND1,GJA1,CTNNB1,DVL2,PPARG,PRKCA
WP3645	NAD+ biosynthetic pathways	0.859629009679942	-0.15125436690056	22	6	0.0031413612565445	1910	5310	51547,952,3620,10038,8658,80351	SIRT7,CD38,IDO1,PARP2,TNKS,TNKS2
WP272	Blood Clotting Cascade	0.859629009679942	-0.15125436690056	22	6	0.0031413612565445	1910	5310	2155,7450,5340,2158,2159,2147	F7,VWF,PLG,F9,F10,F2
WP3301	MFAP5-mediated ovarian cancer cell motility and invasiveness	0.864605328273817	-0.145482144063666	12	3	0.00157068062827225	1910	5310	3725,5588,3685	JUN,PRKCQ,ITGAV
WP2795	Cardiac Hypertrophic Response	0.867449457313434	-0.142198031321347	57	17	0.00890052356020942	1910	5310	9020,5578,4790,7124,4205,1025,3551,10014,3479,5604,5606,5608,5894,208,1022,207,5530	MAP3K14,PRKCA,NFKB1,TNF,MEF2A,CDK9,IKBKB,HDAC5,IGF1,MAP2K1,MAP2K3,MAP2K6,RAF1,AKT2,CDK7,AKT1,PPP3CA
WP384	Apoptosis Modulation by HSP70	0.869796328638731	-0.139496199753316	19	5	0.00261780104712042	1910	5310	356,5602,355,9131,4790	FASLG,MAPK10,FAS,AIFM1,NFKB1
WP501	GPCRs, Class C Metabotropic glutamate, pheromone	0.882909353393445	-0.12453274118639	16	4	0.00209424083769634	1910	5310	2918,2550,2911,2912	GRM8,GABBR1,GRM1,GRM2
WP3875	ATR Signaling	0.890645921155208	-0.115808325381134	9	2	0.00104712041884817	1910	5310	5810,11073	RAD1,TOPBP1
WP531	Mismatch repair	0.890645921155208	-0.115808325381134	9	2	0.00104712041884817	1910	5310	2956,5111	MSH6,PCNA
WP288	NLR Proteins	0.890645921155208	-0.115808325381134	9	2	0.00104712041884817	1910	5310	958,3551	CD40,IKBKB
WP3674	Tgif disruption of Shh signaling	0.890645921155208	-0.115808325381134	9	2	0.00104712041884817	1910	5310	4087,60436	SMAD2,TGIF2
WP2868	TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer	0.892486700390152	-0.113743666963011	5	1	0.000523560209424084	1910	5310	3716	JAK1
WP3303	Rac1/Pak1/p38/MMP-2 pathway	0.89789071232551	-0.107706919282665	68	20	0.0104712041884817	1910	5310	1499,4790,6247,5290,5295,4690,4609,6776,3551,5781,207,7157,332,6714,4792,3265,572,581,3845,284	CTNNB1,NFKB1,RS1,PIK3CA,PIK3R1,NCK1,MYC,STAT5A,IKBKB,PTPN11,AKT1,TP53,BIRC5,SRC,NFKBIA,HRAS,BAD,BAX,KRAS,ANGPT1
WP3892	Development of pulmonary dendritic cells and macrophage subsets	0.900180999285032	-0.105159425561093	13	3	0.00157068062827225	1910	5310	3394,3662,1437	IRF8,IRF4,CSF2
WP186	Homologous recombination	0.900180999285032	-0.105159425561093	13	3	0.00157068062827225	1910	5310	4683,5425,57804	NBN,POLD2,POLD4
WP524	G13 Signaling Pathway	0.902957843951762	-0.102079411093705	40	11	0.00575916230366492	1910	5310	8976,1072,5290,1073,6242,5602,9475,6093,5296,5500,998	WASL,CFL1,PIK3CA,CFL2,RTKN,MAPK10,ROCK2,ROCK1,PIK3R2,PPP1CB,CDC42
WP554	ACE Inhibitor Pathway	0.911402125389988	-0.0927710681493819	17	4	0.00209424083769634	1910	5310	5972,1585,10159,1215	REN,CYP11B2,ATP6AP2,CMA1
WP558	Complement and Coagulation Cascades	0.91751209663819	-0.0860895147935231	60	17	0.00890052356020942	1910	5310	7450,5627,5265,2155,714,1191,2159,3053,2147,7035,7056,5340,5104,3998,462,2158,4179	VWF,PROS1,SERPINA1,F7,C1QC,CLU,F10,SERPIND1,F2,TFPI,THBD,PLG,SERPINA5,LMAN1,SERPINC1,F9,CD46
WP3670	Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway	0.922148451457688	-0.0810490581285078	21	5	0.00261780104712042	1910	5310	6839,1728,4780,780,2252	SUV39H1,NQO1,NFE2L2,DDR1,FGF7
WP2333	Trans-sulfuration pathway	0.923536492195182	-0.079544965023184	10	2	0.00104712041884817	1910	5310	4357,27430	MPST,MAT2B
WP117	GPCRs, Other	0.926696245484648	-0.0761294418872334	95	28	0.0146596858638743	1910	5310	4992,3355,2918,27239,1909,2840,1268,26211,23284,10888,140,2833,2837,2925,3577,84539,26648,1814,9289,2911,11245,154,30817,1234,3356,5737,5032,1131	OR1F1,HTR1F,GRM8,GPR162,EDNRA,GPR17,CNR1,OR2F1,ADGRL3,GPR83,ADORA3,CXCR3,UTS2R,GRPR,CXCR1,MCHR2,OR7E24,DRD3,ADGRG1,GRM1,GPR176,ADRB2,ADGRE2,CCR5,HTR2A,PTGFR,P2RY11,CHRM3
WP322	Osteoblast Signaling	0.927088508211342	-0.075706239860389	14	3	0.00157068062827225	1910	5310	3685,632,8074	ITGAV,BGLAP,FGF23
WP1981	Thyroxine (Thyroid Hormone) Production	0.931195541544199	-0.0712859898770368	6	1	0.000523560209424084	1910	5310	7253	TSHR
WP694	Arylamine metabolism	0.931195541544199	-0.0712859898770368	6	1	0.000523560209424084	1910	5310	10	NAT2
WP2572	Primary Focal Segmental Glomerulosclerosis FSGS	0.93435687601048	-0.0678968195030689	74	21	0.0109947643979058	1910	5310	3913,23607,3664,7099,4311,4690,3685,1027,9076,3611,1499,3856,81,4040,5111,1026,977,1605,207,941,22943	LAMB2,CD2AP,IRF6,TLR4,MME,NCK1,ITGAV,CDKN1B,CLDN1,ILK,CTNNB1,KRT8,ACTN4,LRP6,PCNA,CDKN1A,CD151,DAG1,AKT1,CD80,DKK1
WP2525	Trans-sulfuration and one carbon metabolism	0.93442754821071	-0.0678211850967166	32	8	0.00418848167539267	1910	5310	4144,2729,6470,27430,275,10768,7298,441024	MAT2A,GCLC,SHMT1,MAT2B,AMT,AHCYL1,TYMS,MTHFD2L
WP2643	Nanoparticle-mediated activation of receptor signaling	0.940464608369072	-0.0613812616039967	29	7	0.00366492146596859	1910	5310	3265,3845,5602,5894,5604,10000,6714	HRAS,KRAS,MAPK10,RAF1,MAP2K1,AKT3,SRC
WP1584	Type II diabetes mellitus	0.94053652257119	-0.0613047978518279	22	5	0.00261780104712042	1910	5310	122809,3551,9370,7124,3767	SOCS4,IKBKB,ADIPOQ,TNF,KCNJ11
WP167	Eicosanoid Synthesis	0.94053652257119	-0.0613047978518279	22	5	0.00261780104712042	1910	5310	5730,1800,50640,9536,241	PTGDS,DPEP1,PNPLA8,PTGES,ALOX5AP
WP2513	Nanoparticle triggered regulated necrosis	0.946925342723889	-0.0545350244645799	11	2	0.00104712041884817	1910	5310	148022,2512	TICAM1,FTL
WP3630	NAD metabolism, sirtuins and aging	0.946925342723889	-0.0545350244645799	11	2	0.00104712041884817	1910	5310	5468,4790	PPARG,NFKB1
WP3651	Pathways Affected in Adenoid Cystic Carcinoma	0.948897570204337	-0.0524544206503053	66	18	0.00942408376963351	1910	5310	10933,6605,55783,4149,4609,5290,2033,1487,7157,207,672,5894,3265,8823,93986,5728,55294,1387	MORF4L1,SMARCE1,CMTR2,MAX,MYC,PIK3CA,EP300,CTBP1,TP53,AKT1,BRCA1,RAF1,HRAS,FGF16,FOXP2,PTEN,FBXW7,CREBBP
WP2011	SREBF and miR33 in cholesterol and lipid homeostasis	0.950540441101194	-0.0507245707718112	19	4	0.00209424083769634	1910	5310	3949,3157,693120,5465	LDLR,HMGCS1,MIR33B,PPARA
WP241	One Carbon Metabolism	0.953454342351405	-0.0476637393551624	30	7	0.00366492146596859	1910	5310	6470,27430,7298,275,2745,10588,10840	SHMT1,MAT2B,TYMS,AMT,GLRX,MTHFS,ALDH1L1
WP455	GPCRs, Class A Rhodopsin-like	0.954720476009309	-0.0463366766232407	259	81	0.0424083769633508	1910	5310	5028,7932,2859,10161,10936,4992,27334,54328,64805,1268,1235,7852,4829,2838,11255,140,81696,1132,29909,2833,2861,10798,2831,4987,5030,283297,3350,3577,553,1128,442186,154,1233,5732,155,5021,2845,1814,153,1234,1236,442191,4887,5737,5032,729230,2857,2847,5731,3355,26211,2825,1524,1133,1909,2840,57007,10888,54329,187,134,2925,9283,4886,1230,148,5734,1812,26493,27198,4988,4986,3274,1232,4889,3361,1131,26692,680,3356,8477	P2RY1,OR2H2,GPR35,LPAR6,GPR75,OR1F1,P2RY10,GPR173,P2RY12,CNR1,CCR6,CXCR4,NMBR,GPR15,HRH3,ADORA3,OR5V1,CHRM4,GPR171,CXCR3,GPR37,OR5I1,NPBWR1,OPRL1,P2RY4,OR10A4,HTR1A,CXCR1,AVPR1B,CHRM1,OR2J3,ADRB2,CCR4,PTGER2,ADRB3,OXTR,GPR22,DRD3,ADRB1,CCR5,CCR7,OR14J1,NPY2R,PTGFR,P2RY11,CCR2,GPR34,MCHR1,PTGER1,HTR1F,OR2F1,CMKLR2,CX3CR1,CHRM5,EDNRA,GPR17,ACKR3,GPR83,GPR85,APLNR,ADORA1,GRPR,GPR37L1,NPY1R,CCR1,ADRA1A,PTGER4,DRD1,OR8B8,HCAR1,OPRM1,OPRK1,HRH2,CCR3,NPY5R,HTR5A,CHRM3,OR2W1,BRS3,HTR2A,GPR65
WP2596	Gastric acid production	0.955972411015023	-0.0450262251180545	7	1	0.000523560209424084	1910	5310	7432	VIP
WP3845	Canonical  and Non-canonical Notch signaling	0.959464759157371	-0.0413796925493001	27	6	0.0031413612565445	1910	5310	65989,4236,5664,4853,5663,3516	DLK2,MFAP1,PSEN2,NOTCH2,PSEN1,RBPJ
WP2035	Follicle Stimulating Hormone (FSH) signaling pathway	0.959464759157371	-0.0413796925493001	27	6	0.0031413612565445	1910	5310	6009,5894,1385,5578,6714,207	RHEB,RAF1,CREB1,PRKCA,SRC,AKT1
WP1433	Nucleotide-binding Oligomerization Domain (NOD) pathway	0.960312586020221	-0.0404964370820995	41	10	0.00523560209424084	1910	5310	29108,55655,14,3551,22861,3553,114548,4792,3606,3320	PYCARD,NLRP2,AAMP,IKBKB,NLRP1,IL1B,NLRP3,NFKBIA,IL18,HSP90AA1
WP47	Hedgehog Signaling Pathway	0.962007798578308	-0.0387327217190318	16	3	0.00157068062827225	1910	5310	25942,10284,51684	SIN3A,SAP18,SUFU
WP383	Striated Muscle Contraction	0.963970890456096	-0.0366941814498255	38	9	0.00471204188481675	1910	5310	59,7139,7125,7111,7135,1674,8557,7170,81	ACTA2,TNNT2,TNNC2,TMOD1,TNNI1,DES,TCAP,TPM3,ACTN4
WP2361	Gastric Cancer Network 1	0.969039153030007	-0.0314502623039331	28	6	0.0031413612565445	1910	5310	4173,4605,8209,8607,57122,86	MCM4,MYBL2,GATD3,RUVBL1,NUP107,ACTL6A
WP2853	Endoderm Differentiation	0.970810478061825	-0.0296240119639728	145	42	0.0219895287958115	1910	5310	4830,7709,5606,57690,6478,23576,22943,5744,2146,4088,442918,406933,6928,6422,10459,6772,6657,4089,80155,657,6671,5083,4087,9760,2005,5015,26986,5460,79577,85363,54892,8554,31,9350,1499,494324,9241,2131,11166,55832,6001,29970	NME1,ZBTB17,MAP2K3,TNRC6C,SIAH2,DDAH1,DKK1,PTHLH,EZH2,SMAD3,MIR373,MIR141,HNF1B,SFRP1,MAD2L2,STAT1,SOX2,SMAD4,NAA15,BMPR1A,SP4,PAX9,SMAD2,TOX,ELK4,OTX2,PABPC1,POU5F1,CDC73,TRIM5,NCAPG2,PIAS1,ACACA,CER1,CTNNB1,MIR375,NOG,EXT1,SOX21,CAND1,RGS10,SCHIP1
WP268	Notch Signaling Pathway	0.972202861723568	-0.028190790820734	46	11	0.00575916230366492	1910	5310	5664,23385,1487,3516,51763,1856,171558,5663,1387,51107,4853	PSEN2,NCSTN,CTBP1,RBPJ,INPP5K,DVL2,PTCRA,PSEN1,CREBBP,APH1A,NOTCH2
WP2118	Arrhythmogenic Right Ventricular Cardiomyopathy	0.972744071440579	-0.0276342617743617	76	20	0.0104712041884817	1910	5310	1495,3685,3673,2697,1499,60,3696,784,81,785,3728,10368,783,4000,3693,6546,1496,3655,1674,1605	CTNNA1,ITGAV,ITGA2,GJA1,CTNNB1,ACTB,ITGB8,CACNB3,ACTN4,CACNB4,JUP,CACNG3,CACNB2,LMNA,ITGB5,SLC8A1,CTNNA2,ITGA6,DES,DAG1
WP2064	Neural Crest Differentiation	0.974139684846039	-0.0262005720227194	102	28	0.0146596858638743	1910	5310	3397,27022,79885,2705,1499,4790,3516,6662,388,6591,4359,10014,4609,1005,8841,3211,7976,4853,4286,9355,2260,1856,4487,23493,4086,10013,4488,5376	ID1,FOXD3,HDAC11,GJB1,CTNNB1,NFKB1,RBPJ,SOX9,RHOB,SNAI2,MPZ,HDAC5,MYC,CDH7,HDAC3,HOXB1,FZD3,NOTCH2,MITF,LHX2,FGFR1,DVL2,MSX1,HEY2,SMAD1,HDAC6,MSX2,PMP22
WP3668	Hypothesized Pathways in Pathogenesis of Cardiovascular Disease	0.97459351069698	-0.0257348070219663	25	5	0.00261780104712042	1910	5310	4087,4088,4089,6464,7048	SMAD2,SMAD3,SMAD4,SHC1,TGFBR2
WP692	Sulfation Biotransformation Reaction	0.980713909568565	-0.0194744933780661	18	3	0.00157068062827225	1910	5310	9060,27284,2539	PAPSS2,SULT1B1,G6PD
WP3925	Amino Acid metabolism	0.980965494808123	-0.0192179935235271	91	24	0.012565445026178	1910	5310	1743,4953,5917,5091,8974,6723,4190,5160,2184,4942,3939,3176,4594,2752,4357,1962,3033,50,3417,5831,10993,549,1621,384	DLST,ODC1,RARS1,PC,P4HA2,SRM,MDH1,PDHA1,FAH,OAT,LDHA,HNMT,MMUT,GLUL,MPST,EHHADH,HADH,ACO2,IDH1,PYCR1,SDS,AUH,DBH,ARG2
WP698	Glucuronidation	0.981099706209925	-0.019081187262511	26	5	0.00261780104712042	1910	5310	7358,79799,54658,7360,5236	UGDH,UGT2A3,UGT1A1,UGP2,PGM1
WP325	Triacylglyceride Synthesis	0.981099706209925	-0.019081187262511	26	5	0.00261780104712042	1910	5310	2712,8443,55326,10554,57678	GK2,GNPAT,AGPAT5,AGPAT1,GPAM
WP561	Heme Biosynthesis	0.981977988766442	-0.0181863855770082	9	1	0.000523560209424084	1910	5310	3145	HMBS
WP2855	Dopaminergic Neurogenesis	0.982253142010907	-0.0179062217592651	30	6	0.0031413612565445	1910	5310	5015,6531,4929,6657,4487,63973	OTX2,SLC6A3,NR4A2,SOX2,MSX1,NEUROG2
WP3915	Angiopoietin Like Protein 8 Regulatory Pathway	0.98743123241982	-0.0126484226875809	132	36	0.018848167539267	1910	5310	9020,6655,10211,6513,5290,4215,8986,5596,5894,1581,208,867,5296,5294,7786,4296,1977,53358,5564,3265,5770,2203,143686,6464,5295,5571,5604,6009,5608,5606,207,5602,2997,1734,2931,8503	MAP3K14,SOS2,FLOT1,SLC2A1,PIK3CA,MAP3K3,RPS6KA4,MAPK4,RAF1,CYP7A1,AKT2,CBL,PIK3R2,PIK3CG,MAP3K12,MAP3K11,EIF4E,SHC3,PRKAB1,HRAS,PTPN1,FBP1,SESN3,SHC1,PIK3R1,PRKAG1,MAP2K1,RHEB,MAP2K6,MAP2K3,AKT1,MAPK10,GYS1,DIO2,GSK3A,PIK3R3
WP2406	Cardiac Progenitor Differentiation	0.987636023320378	-0.0124410465582902	53	12	0.00628272251308901	1910	5310	9241,7852,649,5080,7139,6657,22943,7070,3479,4208,3815,5460	NOG,CXCR4,BMP1,PAX6,TNNT2,SOX2,DKK1,THY1,IGF1,MEF2C,KIT,POU5F1
WP3527	Preimplantation Embryo	0.987818664312686	-0.0122561362245105	60	14	0.00732984293193717	1910	5310	55506,3662,360,6657,1649,4084,8538,9314,3182,5460,57504,1958,3159,476	MACROH2A2,IRF4,AQP3,SOX2,DDIT3,MXD1,BARX2,KLF4,HNRNPAB,POU5F1,MTA3,EGR1,HMGA1,ATP1A1
WP2874	Liver X Receptor Pathway	0.988471488388413	-0.0115954800970891	10	1	0.000523560209424084	1910	5310	1581	CYP7A1
WP3601	Composition of Lipid Particles	0.988471488388413	-0.0115954800970891	10	1	0.000523560209424084	1910	5310	3949	LDLR
WP334	GPCRs, Class B Secretin-like	0.989747552864023	-0.0103053654778392	24	4	0.00209424083769634	1910	5310	7433,23284,1394,30817	VIPR1,ADGRL3,CRHR1,ADGRE2
WP3644	NAD+ metabolism	0.992096122235066	-0.00793527897713472	16	2	0.00104712041884817	1910	5310	952,51547	CD38,SIRT7
WP430	Statin Pathway	0.992593435702394	-0.00743412908621313	33	6	0.0031413612565445	1910	5310	693120,2222,64714,344,1581,3949	MIR33B,FDFT1,PDIA2,APOC2,CYP7A1,LDLR
WP2854	Gene regulatory network modelling somitogenesis	0.992626102969576	-0.00740121860296566	11	1	0.000523560209424084	1910	5310	2043	EPHA4
WP2879	Farnesoid X Receptor  Pathway	0.997586018972695	-0.00241689937701148	19	2	0.00104712041884817	1910	5310	1581,11309	CYP7A1,SLCO2B1
WP2857	Mesodermal Commitment Pathway	0.998670972516461	-0.00132991142383961	155	39	0.0204188481675393	1910	5310	442918,406933,10124,2260,203228,6657,5080,595,4089,657,4087,4780,23576,22943,659,4086,4088,8554,31,80304,494324,9241,2131,11166,6001,29970,9760,2005,406983,2303,8322,3717,5460,9314,8553,57045,85363,54892,90	MIR373,MIR141,ARL4A,FGFR1,C9orf72,SOX2,PAX6,CCND1,SMAD4,BMPR1A,SMAD2,NFE2L2,DDAH1,DKK1,BMPR2,SMAD1,SMAD3,PIAS1,ACACA,WDCP,MIR375,NOG,EXT1,SOX21,RGS10,SCHIP1,TOX,ELK4,MIR200A,FOXC2,FZD4,JAK2,POU5F1,KLF4,BHLHE40,TWSG1,TRIM5,NCAPG2,ACVR1
WP2291	Deregulation of Rab and Rab Effector Genes in Bladder Cancer	0.999211824271019	-0.000788486502778231	16	1	0.000523560209424084	1910	5310	5873	RAB27A
WP2369	Histone Modifications	0.999810528778163	-0.000189489173776495	69	12	0.00628272251308901	1910	5310	133383,54093,64754,2146,6839,80854,8726,2145,55209,84193,8350,51111	SETD9,SETD4,SMYD3,EZH2,SUV39H1,SETD7,EED,EZH1,SETD5,SETD3,H3C1,KMT5B
WP545	Complement Activation	0.999946320790416	-5.36806503639303e-05	22	1	0.000523560209424084	1910	5310	714	C1QC
WP2646	Lidocaine metabolism	0.999999999998398	-1.60177426877794e-12	2	0	0	1910	5310
WP2816	Felbamate Metabolism	0.999999999998398	-1.60177426877794e-12	2	0	0	1910	5310
WP3627	Gut-Liver Indole Metabolism	1.0000000000052	5.2020054930324e-12	1	0	0	1910	5310
WP2190	One carbon donor	1.0000000000052	5.2020054930324e-12	1	0	0	1910	5310
WP3191	TSLP Signaling Pathway	1.0000000000052	5.2020054930324e-12	1	0	0	1910	5310
WP188	Focal Adhesion	1.0000000000052	5.2020054930324e-12	1	0	0	1910	5310
WP1	Statin Pathway	1.0000000000052	5.2020054930324e-12	1	0	0	1910	5310
WP661	Glucose Homeostasis	1.0000000000052	5.2020054930324e-12	1	0	0	1910	5310
WP2536	Colchicine Metabolic Pathway	1.0000000000052	5.2020054930324e-12	1	0	0	1910	5310
WP2485	NAD Biosynthesis II (from tryptophan)	1.00000000000884	8.83885884405897e-12	8	0	0	1910	5310
WP3407	FTO Obesity Variant Mechanism	1.00000000000884	8.83885884405897e-12	8	0	0	1910	5310
WP1603	Nicotine Activity on Chromaffin Cells	1.00000000000912	9.12162706478981e-12	4	0	0	1910	5310