Galilee blind mole rat 🐾 Species
Tissues 1
Whole brain
Species / Rodents / Galilee blind mole rat

Galilee blind mole rat

Spalax galili
Rodents
20 yrs
Max Lifespan
150 g
Adult Weight
SP116
Species ID
2
Tissues
📊Statistics 🧬Analysis
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Species Overview

A subterranean rodent (family Spalacidae) endemic to the basalt soils of the Upper Galilee in northern Israel. Adults weigh 100–200 g with a cylindrical body, no visible eyes (vestigial and covered by skin), no external ears, and a very short tail. Massive, protruding incisors are used for digging tunnels. Fur is velvety, grayish-brown. They live entirely underground in sealed burrow systems, feeding on roots, bulbs, and tubers. They are fiercely solitary and territorial. Their adaptations to the subterranean environment are extraordinary: tolerance of severe hypoxia and hypercapnia (high CO?), as oxygen levels in their tunnels can drop dangerously low. Most remarkably, blind mole rats exhibit extreme resistance to cancer—they virtually never develop spontaneous tumors. This has been linked to massive necrotic cell death triggered by interferon-β when cells reach high density. They are a premier model for hypoxia adaptation, cancer resistance, and speciation (four chromosomal species exist in Israel). Lifespan exceeds 20 years.
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1Systems
Nervous system
Nervous system
ID: sys01
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1Tissues
Whole brain
Whole brain
ID: sys01tis16System: Nervous system
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6Cell Types
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Abbr: EnteroMajor: Epithelial cell…
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Abbr: HepMajor: Epithelial cell…
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Abbr: INMajor: Neural cells
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Abbr: MicrogliaMajor: Immune cells
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Abbr: PeriMajor: Stromal cells
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Abbr: SpermatocyteMajor: Germ cells
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Species-Related Single-Cell Datasets
1Datasets
DataID ↕ Latin Name ↕ Folder ID ↕ Tissue ↕ Title ↕ Detail QC Analysis
Data1239 Nannospalax galili Nannospalax_galili_31835035_2019_Rank0001 Brain Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program QC Analysis

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