Fasciculata cells

Fasciculata cells are steroidogenic endocrine cells that constitute the zona fasciculata, the middle and largest layer of the adrenal cortex. Their primary function is the production of glucocorticoids (mainly cortisol in humans), stimulated by ACTH from the pituitary. They contain abundant lipid droplets with cholesterol esters (giving a "foamy" appearance) and smooth endoplasmic reticulum for steroid hormone synthesis.