Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
6.513e-09	-18.85	integrin-mediated signaling pathway	biological process	GO:0007229	96	7	18204	49	DAB2,ITGAL,ITGAV,FYB1,ITGB2,HCK,TLN1
1.575e-08	-17.97	PH-like_dom_sf	interpro domains	IPR011993	431	11	18521	50	GAB1,TLN1,ARHGAP24,ARAP1,PREX1,DNM2,DAB2,ARHGEF18,AKAP13,WDFY3,SH2B3
1.085e-07	-16.04	regulation of small GTPase mediated signal transduction	biological process	GO:0051056	306	9	18204	49	PREX1,ARAP1,AKAP13,DOCK8,DOCK2,ARHGAP24,ARHGEF18,ARHGAP45,ITGAV
1.206e-07	-15.93	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	gene3d domains	2.30.29.30	431	11	14470	48	DAB2,SH2B3,DNM2,WDFY3,ARHGEF18,ARAP1,GAB1,PREX1,TLN1,ARHGAP24,AKAP13
1.295e-07	-15.86	signal transduction	biological process	GO:0007165	4637	30	18204	49	DNM2,RGL1,GAB1,PTPN6,RXRA,DISC1,PLXND1,ARAP1,ITGB2,HCK,SPI1,ZFP36L1,ARHGEF18,DAB2,ITGAL,CD74,MCOLN2,DOCK8,AKAP13,RBPJ,DOCK2,PTGIR,FYB1,TLN1,TMSB4X,PREX1,SH2B3,ITGAV,ARHGAP45,ARHGAP24
1.385e-07	-15.79	regulation of cell adhesion	biological process	GO:0030155	807	13	18204	49	RBPJ,PTPN6,CD74,DOCK8,SH2B3,SPI1,ITGAV,DAB2,DISC1,PLXND1,ITGB2,PREX1,TLN1
1.388e-07	-15.79	T cell activation	biological process	GO:0042110	315	9	18204	49	ITGAL,ZFP36L1,PTPN6,SPI1,DOCK2,PREX1,DOCK8,ELF4,CD74
1.480e-07	-15.73	signaling	biological process	GO:0023052	4968	31	18204	49	PTGIR,RBPJ,DOCK2,DOCK8,AKAP13,MCOLN2,CD74,ARHGAP45,ITGAV,ARHGAP24,SH2B3,STAB1,TMSB4X,TLN1,PREX1,FYB1,RXRA,PTPN6,GAB1,RGL1,DNM2,ARHGEF18,DAB2,ITGAL,ZFP36L1,SPI1,ARAP1,PLXND1,DISC1,ITGB2,HCK
1.821e-07	-15.52	cell communication	biological process	GO:0007154	5010	31	18204	49	DNM2,RGL1,GAB1,PTPN6,RXRA,ITGB2,HCK,DISC1,PLXND1,ARAP1,SPI1,ARHGEF18,DAB2,ZFP36L1,ITGAL,CD74,MCOLN2,DOCK8,AKAP13,DOCK2,RBPJ,PTGIR,FYB1,PREX1,TLN1,TMSB4X,STAB1,SH2B3,ARHGAP24,ITGAV,ARHGAP45
2.848e-07	-15.07	PLCG1 (phospholipase C gamma 1)	protein interactions	5335	258	8	19454	50	PTPN12,GAB1,DISC1,TLN1,PTPN6,EHD4,HCK,SH2B3
3.458e-07	-14.88	cell activation	biological process	GO:0001775	725	12	18204	49	TLN1,PREX1,ITGB2,ELF4,ITGAL,ZFP36L1,SPI1,DOCK8,CD74,PTPN6,DOCK2,RBPJ
4.176e-07	-14.69	leukocyte activation	biological process	GO:0045321	599	11	18204	49	SPI1,ITGAL,ZFP36L1,ELF4,ITGB2,PREX1,RBPJ,PTPN6,DOCK2,CD74,DOCK8
4.478e-07	-14.62	lymphocyte activation	biological process	GO:0046649	476	10	18204	49	DOCK8,PREX1,ELF4,CD74,ZFP36L1,ITGAL,RBPJ,SPI1,DOCK2,PTPN6
5.191e-07	-14.47	PH_domain	interpro domains	IPR001849	266	8	18521	50	ARHGEF18,AKAP13,GAB1,ARAP1,ARHGAP24,PREX1,DNM2,SH2B3
6.280e-07	-14.28	GTPase regulator activity	molecular function	GO:0030695	491	10	18094	49	ARAP1,DOCK2,PREX1,ARHGAP24,DOCK8,RGL1,PTGIR,ARHGAP45,AKAP13,ARHGEF18
6.280e-07	-14.28	nucleoside-triphosphatase regulator activity	molecular function	GO:0060589	491	10	18094	49	ARAP1,DOCK2,PREX1,ARHGAP24,DOCK8,RGL1,PTGIR,ARHGAP45,AKAP13,ARHGEF18
6.285e-07	-14.28	cell migration	biological process	GO:0016477	921	13	18204	49	DOCK8,MCOLN2,DOCK2,BTG1,GAB1,DISC1,PLXND1,PREX1,ITGB2,HCK,ITGAV,ARHGAP24,ITGAL
6.889e-07	-14.19	endocytosis	biological process	GO:0006897	499	10	18204	49	DOCK2,STAB1,DAB2,ITGAL,ITGAV,MYO1F,EHD4,HCK,DNM2,ITGB2
7.874e-07	-14.05	response to stimulus	biological process	GO:0050896	7803	38	18204	49	MCOLN2,CD74,AKAP13,DOCK8,DOCK2,RBPJ,CCND2,CD68,PTGIR,FYB1,ME1,TLN1,TMSB4X,PREX1,SH2B3,PTPN12,STAB1,ARHGAP24,ARHGAP45,ITGAV,FKBP5,RGL1,DNM2,PTPN6,GAB1,RXRA,EHD4,HCK,ITGB2,ARAP1,DISC1,PLXND1,SPI1,TFEB,ITGAL,DAB2,ZFP36L1,ARHGEF18
8.058e-07	-14.03	PTK2 (protein tyrosine kinase 2)	protein interactions	5747	296	8	19454	50	ITGB2,DNM2,HCK,TLN1,PTPN6,FKBP5,PTPN12,ITGAV
1.167e-06	-13.66	cell periphery	cellular component	GO:0071944	6020	32	19108	49	ITGB2,HCK,ARHGAP45,HEPHL1,ARAP1,PTPN6,CD74,PLXND1,RGL1,STAB1,SEPTIN9,AKAP13,ITM2B,DAB2,DNM2,MYO1F,CD68,ITGAV,TLN1,SH2B3,SLC9A7,DOCK2,ITGAL,ARHGEF18,PTGIR,FYB1,DOCK8,PREX1,WDFY3,EHD4,ANTXR2,MCOLN2
1.606e-06	-13.34	import into cell	biological process	GO:0098657	687	11	18204	49	DOCK2,MYO1F,DNM2,STAB1,DAB2,ITGAL,ITGAV,EHD4,HCK,ITGB2,SLC9A7
1.906e-06	-13.17	immune system process	biological process	GO:0002376	1991	18	18204	49	FYB1,ELF4,HCK,ITGB2,PREX1,SPI1,SH2B3,ZFP36L1,ITGAL,TFEB,CD74,MCOLN2,DNM2,DOCK8,DOCK2,PTPN6,RBPJ,CD68
2.520e-06	-12.89	guanyl-nucleotide exchange factor activity	molecular function	GO:0005085	228	7	18094	49	AKAP13,ARHGEF18,DOCK8,RGL1,DOCK2,PTGIR,PREX1
2.650e-06	-12.84	plasma membrane	cellular component	GO:0005886	5538	30	19108	49	DOCK2,SLC9A7,ITGAL,ARHGEF18,PTGIR,ITGAV,TLN1,SH2B3,MCOLN2,FYB1,ANTXR2,PREX1,WDFY3,EHD4,DOCK8,CD74,PTPN6,PLXND1,ITGB2,HCK,ARAP1,ARHGAP45,HEPHL1,DNM2,DAB2,ITM2B,CD68,MYO1F,STAB1,RGL1
3.057e-06	-12.70	cellular response to stimulus	biological process	GO:0051716	6307	33	18204	49	ARHGAP45,ITGAV,ARHGAP24,SH2B3,TLN1,PREX1,TMSB4X,FYB1,PTGIR,CD68,CCND2,RBPJ,DOCK2,DOCK8,AKAP13,MCOLN2,CD74,TFEB,ZFP36L1,ITGAL,DAB2,ARHGEF18,SPI1,ARAP1,DISC1,PLXND1,ITGB2,HCK,RXRA,PTPN6,GAB1,RGL1,DNM2
3.153e-06	-12.67	regulation of response to stimulus	biological process	GO:0048583	4104	26	18204	49	HCK,ITGB2,ARAP1,DISC1,RBM47,SPI1,ARHGEF18,DAB2,PTPN6,RXRA,FYB1,ELF4,PREX1,TMSB4X,PTPN12,SH2B3,ARHGAP24,BMP2K,ARHGAP45,ITGAV,CD74,AKAP13,DOCK8,DOCK2,RBPJ,PTGIR
3.492e-06	-12.56	regulation of developmental process	biological process	GO:0050793	2540	20	18204	49	ARHGEF18,DAB2,BMP2K,ZFP36L1,ITGAV,SPI1,STAB1,PREX1,ITGB2,HCK,ARAP1,DISC1,PLXND1,RXRA,PTPN6,BTG1,GAB1,RBPJ,DNM2,CD74
4.596e-06	-12.29	cell motility	biological process	GO:0048870	1101	13	18204	49	DOCK2,GAB1,BTG1,DOCK8,MCOLN2,ARHGAP24,ITGAL,ITGAV,PREX1,ITGB2,HCK,DISC1,PLXND1
4.852e-06	-12.24	cytoplasm	cellular component	GO:0005737	12081	45	19108	49	DISC1,CD74,PTPN12,HCK,CD68,DAB2,DNM2,RBPJ,SEPTIN9,BMP2K,STAB1,PTGIR,ITGAL,RBM47,DOCK2,TLN1,ITGAV,MCOLN2,ARHGAP24,PREX1,DOCK8,FYB1,PTPN6,BTG1,ME1,ARHGAP45,ARAP1,ITGB2,GAB1,MYO1F,TFEB,ITM2B,FKBP5,AKAP13,RGL1,ZFP36L1,CCND2,ARHGEF18,SLC9A7,SH2B3,RXRA,EHD4,TMSB4X,WDFY3,ANTXR2
5.347e-06	-12.14	regulation of signal transduction	biological process	GO:0009966	3114	22	18204	49	RXRA,PTGIR,DOCK2,PTPN6,RBPJ,AKAP13,DOCK8,CD74,ARHGEF18,BMP2K,DAB2,ARHGAP24,ITGAV,ARHGAP45,SPI1,RBM47,SH2B3,PTPN12,PREX1,TMSB4X,DISC1,ARAP1
6.316e-06	-11.97	Hemostasis	REACTOME pathways	R-HSA-109582	632	11	10285	36	TLN1,PTPN6,SH2B3,TMSB4X,PTGIR,ITGAV,ITGB2,ITGAL,DOCK8,CD74,DOCK2
6.442e-06	-11.95	integrin alphaL-beta2 complex	cellular component	GO:0034687	2	2	19108	49	ITGAL,ITGB2
6.508e-06	-11.94	cytoplasmic vesicle	cellular component	GO:0031410	2521	19	19108	49	PTPN6,DISC1,SLC9A7,DOCK2,CD74,ITGAL,ITGAV,ITGB2,HCK,ARHGAP45,ITM2B,DAB2,DNM2,MCOLN2,CD68,STAB1,TMSB4X,EHD4,ANTXR2
6.741e-06	-11.91	intracellular vesicle	cellular component	GO:0097708	2527	19	19108	49	ANTXR2,TMSB4X,EHD4,STAB1,CD68,MCOLN2,DNM2,DAB2,ITM2B,ARHGAP45,ITGB2,HCK,ITGAV,ITGAL,DOCK2,CD74,PTPN6,DISC1,SLC9A7
7.867e-06	-11.75	cytosol	cellular component	GO:0005829	5475	29	19108	49	ME1,DISC1,PTPN6,ARAP1,ARHGAP45,HCK,PTPN12,MYO1F,TFEB,GAB1,DNM2,DAB2,AKAP13,FKBP5,RGL1,ARHGEF18,CCND2,PTGIR,ZFP36L1,DOCK2,RXRA,SH2B3,ITGAV,TLN1,DOCK8,WDFY3,TMSB4X,PREX1,FYB1
8.149e-06	-11.72	DOK1 (docking protein 1)	protein interactions	1796	50	4	19454	50	PTPN6,TLN1,HCK,ITGB2
8.629e-06	-11.66	Rho GTPase cycle	REACTOME pathways	R-HSA-194840	142	6	10285	36	AKAP13,ARHGAP45,PREX1,ARAP1,ARHGAP24,ARHGEF18
9.075e-06	-11.61	cytoplasmic vesicle membrane	cellular component	GO:0030659	1230	13	19108	49	ITGAL,SLC9A7,CD74,ITGAV,ITGB2,MCOLN2,CD68,DAB2,ITM2B,DNM2,EHD4,ANTXR2,STAB1
1.019e-05	-11.49	PH	smart domains	SM00233	259	8	9717	41	PREX1,ARHGAP24,AKAP13,GAB1,ARAP1,ARHGEF18,DNM2,SH2B3
1.089e-05	-11.43	vesicle membrane	cellular component	GO:0012506	1251	13	19108	49	ITGAL,CD74,SLC9A7,ITGB2,ITGAV,CD68,MCOLN2,DNM2,DAB2,ITM2B,ANTXR2,EHD4,STAB1
1.177e-05	-11.35	focal adhesion	cellular component	GO:0005925	427	8	19108	49	DAB2,DNM2,ARHGAP24,TLN1,PTPN12,ITGAV,HCK,ITGB2
1.337e-05	-11.22	VAV1 (vav guanine nucleotide exchange factor 1)	protein interactions	7409	204	6	19454	50	DOCK2,SPI1,GAB1,PTPN6,HCK,DNM2
1.366e-05	-11.20	anchoring junction	cellular component	GO:0070161	902	11	19108	49	FYB1,ARHGAP24,DNM2,DAB2,GAB1,ITGB2,HCK,ITGAV,PTPN12,TLN1,PTPN6
1.391e-05	-11.18	cell-substrate junction	cellular component	GO:0030055	437	8	19108	49	PTPN12,TLN1,ITGAV,HCK,ITGB2,DAB2,DNM2,ARHGAP24
1.927e-05	-10.86	response to external stimulus	biological process	GO:0009605	1882	16	18204	49	CD74,MCOLN2,FKBP5,DOCK2,GAB1,PTPN6,RBPJ,PTGIR,CD68,HCK,ITGB2,PREX1,DISC1,STAB1,TFEB,ITGAV
2.152e-05	-10.75	ICAM-3 receptor activity	molecular function	GO:0030369	3	2	18094	49	ITGAL,ITGB2
2.358e-05	-10.66	lamellipodium membrane	cellular component	GO:0031258	22	3	19108	49	ITGAV,PLXND1,DOCK8
2.622e-05	-10.55	SRC (SRC proto-oncogene, non-receptor tyrosine kinase)	protein interactions	6714	624	9	19454	50	MCOLN2,RXRA,TLN1,PTPN6,DNM2,HCK,FYB1,GAB1,DAB2
3.078e-05	-10.39	nef (Nef)	protein interactions	156110	802	10	19454	50	RXRA,HCK,EHD4,DNM2,CD74,ITGAL,SLC9A7,TFEB,DAB2,DOCK2
3.124e-05	-10.37	INPP5D (inositol polyphosphate-5-phosphatase D)	protein interactions	3635	70	4	19454	50	DAB2,ARAP1,HCK,GAB1
3.430e-05	-10.28	PH_DOMAIN	prosite domains	PS50003	246	7	12186	46	GAB1,DNM2,ARHGEF18,AKAP13,ARHGAP24,ARAP1,PREX1
3.515e-05	-10.26	regulation of cell shape	biological process	GO:0008360	139	5	18204	49	PLXND1,ARAP1,HCK,ITGB2,ARHGEF18
3.643e-05	-10.22	regulation of cellular component organization	biological process	GO:0051128	2455	18	18204	49	SEPTIN9,ITGAV,ARHGAP24,ARHGEF18,BMP2K,DAB2,EHD4,ARAP1,PLXND1,DISC1,TMSB4X,PREX1,TLN1,HCK,BTG1,DOCK2,AKAP13,DNM2
3.907e-05	-10.15	cell surface receptor signaling pathway	biological process	GO:0007166	1992	16	18204	49	PLXND1,DISC1,ITGB2,TLN1,HCK,TMSB4X,FYB1,ITGAV,DAB2,ITGAL,SH2B3,SPI1,CD74,RBPJ,GAB1,PTPN6
4.014e-05	-10.12	MET (MET proto-oncogene, receptor tyrosine kinase)	protein interactions	4233	248	6	19454	50	HCK,CCND2,SH2B3,ITM2B,ITGAV,GAB1
4.083e-05	-10.11	Integrin_dom_sf	interpro domains	IPR032695	25	3	18521	50	ITGAL,ITGAV,ITGB2
4.197e-05	-10.08	positive regulation of cell adhesion	biological process	GO:0045785	486	8	18204	49	PTPN6,DAB2,ITGAV,CD74,PREX1,ITGB2,DISC1,DOCK8
4.233e-05	-10.07	regulation of molecular function	biological process	GO:0065009	2005	16	18204	49	ARAP1,PLXND1,DISC1,PREX1,TMSB4X,ITGB2,HCK,ARHGAP45,ITGAV,ARHGAP24,DAB2,SPI1,DOCK8,CD74,CCND2,RXRA
4.284e-05	-10.06	regulation of signaling	biological process	GO:0023051	3534	22	18204	49	PTGIR,DOCK2,RBPJ,AKAP13,DOCK8,CD74,BMP2K,ARHGAP24,ITGAV,ARHGAP45,SH2B3,PTPN12,PREX1,TMSB4X,RXRA,PTPN6,DAB2,ARHGEF18,SPI1,RBM47,DISC1,ARAP1
4.389e-05	-10.03	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	6	19454	50	GAB1,FYB1,BTG1,DISC1,ARAP1,PTPN12
4.422e-05	-10.03	regulation of cell communication	biological process	GO:0010646	3541	22	18204	49	ARHGAP45,ITGAV,ARHGAP24,DAB2,BMP2K,ARHGEF18,SH2B3,PTPN12,RBM47,SPI1,ARAP1,DISC1,TMSB4X,PREX1,PTGIR,RXRA,RBPJ,PTPN6,DOCK2,DOCK8,AKAP13,CD74
4.816e-05	-9.94	leukocyte migration	biological process	GO:0050900	245	6	18204	49	ITGAL,MCOLN2,HCK,PREX1,ITGB2,DOCK8
5.154e-05	-9.87	T cell proliferation	biological process	GO:0042098	76	4	18204	49	DOCK2,PTPN6,ELF4,DOCK8
5.439e-05	-9.82	positive regulation of cellular process	biological process	GO:0048522	5719	29	18204	49	TMSB4X,PREX1,ELF4,ITGAV,BMP2K,DOCK8,AKAP13,CD74,MCOLN2,CCND2,RBPJ,DOCK2,DISC1,PLXND1,ARAP1,HCK,ITGB2,EHD4,ZFP36L1,DAB2,TFEB,SPI1,RBM47,SEPTIN9,DNM2,RXRA,GAB1,BTG1,PTPN6
5.476e-05	-9.81	specific granule	cellular component	GO:0042581	160	5	19108	49	ITGB2,DOCK2,ITGAV,PTPN6,ITGAL
5.952e-05	-9.73	regulation of intracellular signal transduction	biological process	GO:1902531	1832	15	18204	49	CD74,DOCK8,AKAP13,PTPN6,DOCK2,TMSB4X,PREX1,ARAP1,SPI1,SH2B3,ARHGAP24,ARHGEF18,DAB2,ARHGAP45,ITGAV
6.400e-05	-9.66	regulation of vesicle-mediated transport	biological process	GO:0060627	516	8	18204	49	EHD4,ITGB2,HCK,SPI1,DOCK2,ITGAV,BMP2K,DAB2
6.674e-05	-9.61	phagocytosis	biological process	GO:0006909	159	5	18204	49	DNM2,ITGAL,ITGB2,HCK,ITGAV
6.772e-05	-9.60	integrin complex	cellular component	GO:0008305	31	3	19108	49	ITGAL,ITGAV,ITGB2
6.876e-05	-9.58	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	31	16828	46	PTPN12,GAB1,CCND2,SPI1,ITGAL,ME1,ELF4,HEPHL1,WDFY3,DOCK8,PLXND1,TFEB,HCK,ITGAV,PTGIR,TLN1,SLC9A7,ITGB2,RXRA,DNM2,RBPJ,ARHGEF18,FKBP5,AKAP13,ARHGAP24,DAB2,MYO1F,DOCK2,ARAP1,ANTXR2,DISC1
7.391e-05	-9.51	enzyme binding	molecular function	GO:0019899	2086	16	18094	49	TMSB4X,ITGB2,PTPN6,PREX1,ITGAV,SH2B3,SPI1,RXRA,DOCK2,AKAP13,DNM2,CCND2,RBM47,TFEB,CD74,BTG1
7.735e-05	-9.47	receptor complex	cellular component	GO:0043235	409	7	19108	49	ITGAL,PLXND1,CD74,PTPN6,RXRA,ITGB2,ITGAV
7.905e-05	-9.45	hemopoiesis	biological process	GO:0030097	688	9	18204	49	SH2B3,RBPJ,PTPN6,RBM47,DOCK2,SPI1,ZFP36L1,CD74,PREX1
8.442e-05	-9.38	ntegrin, alpha v. Chain A, domain 3	gene3d domains	2.60.40.1510	26	3	14470	48	ITGB2,ITGAL,ITGAV
9.037e-05	-9.31	SRMS (src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites)	protein interactions	6725	34	3	19454	50	HCK,FKBP5,HEPHL1
9.564e-05	-9.25	leading edge membrane	cellular component	GO:0031256	180	5	19108	49	DOCK8,ARHGAP45,PLXND1,ITGAV,TLN1
9.614e-05	-9.25	actin cytoskeleton organization	biological process	GO:0030036	547	8	18204	49	DNM2,TLN1,TMSB4X,PREX1,ARAP1,DOCK2,ARHGEF18,MYO1F
9.647e-05	-9.25	EBNA-2 (nuclear antigen EBNA-2)	protein interactions	3783761	6	2	19454	50	RBPJ,SPI1
9.684e-05	-9.24	regulation of GTPase activity	biological process	GO:0043087	278	6	18204	49	ARHGAP45,ARHGAP24,ARAP1,PLXND1,DOCK8,PREX1
1.006e-04	-9.20	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	14	18204	49	CD74,MCOLN2,DOCK8,RBPJ,GAB1,BTG1,PTPN6,RXRA,PLXND1,DISC1,SPI1,RBM47,ZFP36L1,DAB2
1.012e-04	-9.20	Rho_GTPase_activation_prot	interpro domains	IPR008936	90	4	18521	50	ARHGAP45,PLXND1,ARAP1,ARHGAP24
1.018e-04	-9.19	Cell surface interactions at the vascular wall	REACTOME pathways	R-HSA-202733	136	5	10285	36	ITGAV,ITGAL,ITGB2,PTPN6,CD74
1.034e-04	-9.18	regulation of B cell differentiation	biological process	GO:0045577	34	3	18204	49	ZFP36L1,PTPN6,SPI1
1.167e-04	-9.06	PTK2B (protein tyrosine kinase 2 beta)	protein interactions	2185	98	4	19454	50	ITGB2,PTPN12,TLN1,PTPN6
1.221e-04	-9.01	lymphocyte differentiation	biological process	GO:0030098	290	6	18204	49	CD74,PREX1,DOCK2,SPI1,RBPJ,ZFP36L1
1.246e-04	-8.99	intracellular signal transduction	biological process	GO:0035556	1505	13	18204	49	PTPN6,DOCK2,RGL1,DOCK8,AKAP13,MCOLN2,ARHGEF18,ZFP36L1,ITGAV,SH2B3,HCK,PREX1,DISC1
1.262e-04	-8.98	T cell differentiation	biological process	GO:0030217	182	5	18204	49	PREX1,ZFP36L1,CD74,SPI1,DOCK2
1.265e-04	-8.98	STK33 (serine/threonine kinase 33)	protein interactions	65975	38	3	19454	50	FKBP5,HCK,TLN1
1.314e-04	-8.94	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	9	19454	50	PTPN12,DAB2,BTG1,GAB1,WDFY3,DNM2,ARAP1,PTPN6,SH2B3
1.340e-04	-8.92	regulation of endocytosis	biological process	GO:0030100	295	6	18204	49	BMP2K,HCK,DAB2,ITGAV,DOCK2,EHD4
1.370e-04	-8.90	positive regulation of biological process	biological process	GO:0048518	6326	30	18204	49	TMSB4X,PREX1,ELF4,FYB1,ITGAV,BMP2K,DOCK8,AKAP13,MCOLN2,CD74,CCND2,RBPJ,DOCK2,ARAP1,PLXND1,DISC1,HCK,ITGB2,EHD4,TFEB,DAB2,ZFP36L1,SEPTIN9,RBM47,SPI1,DNM2,RXRA,PTPN6,GAB1,BTG1
1.421e-04	-8.86	enzyme regulator activity	molecular function	GO:0030234	1305	12	18094	49	PREX1,DOCK2,ARAP1,BMP2K,ARHGAP24,ARHGAP45,PTGIR,DOCK8,RGL1,ARHGEF18,CCND2,AKAP13
1.483e-04	-8.82	regulation of biological process	biological process	GO:0050789	12079	44	18204	49	AKAP13,PTGIR,CD68,DOCK2,PREX1,TLN1,ME1,FYB1,ARHGAP24,STAB1,SH2B3,GAB1,PTPN6,ITGB2,DISC1,PLXND1,EHD4,TFEB,RBM47,ITM2B,DOCK8,CD74,MCOLN2,CCND2,RBPJ,TMSB4X,ELF4,BMP2K,ITGAV,ARHGAP45,PTPN12,DNM2,RGL1,RXRA,BTG1,HCK,SLC9A7,ARAP1,ZFP36L1,DAB2,ITGAL,ARHGEF18,SPI1,SEPTIN9
1.487e-04	-8.81	PH_16	interpro domains	IPR041020	7	2	18521	50	AKAP13,ARHGEF18
1.502e-04	-8.80	hematopoietic progenitor cell differentiation	biological process	GO:0002244	100	4	18204	49	SH2B3,PTPN6,RBM47,SPI1
1.531e-04	-8.78	FGFR4 (fibroblast growth factor receptor 4)	protein interactions	2264	455	7	19454	50	CCND2,DNM2,PTPN6,SEPTIN9,PTPN12,DAB2,GAB1
1.546e-04	-8.77	PH_16	pfam domains	PF17838	7	2	17795	49	AKAP13,ARHGEF18
1.581e-04	-8.75	THRA (thyroid hormone receptor alpha)	protein interactions	7067	106	4	19454	50	RXRA,AKAP13,ARHGAP24,BTG1
1.592e-04	-8.75	PH	pfam domains	PF00169	187	5	17795	49	ARAP1,SH2B3,ARHGAP24,DNM2,GAB1
1.757e-04	-8.65	Focal Adhesion	WikiPathways	WP306	195	6	5310	24	ITGAV,TLN1,HCK,ITGB2,CCND2,ITGAL
1.818e-04	-8.61	cell adhesion mediated by integrin	biological process	GO:0033627	41	3	18204	49	ITGAV,ITGAL,ITGB2
1.834e-04	-8.60	ITGA1 (integrin subunit alpha 1)	protein interactions	3672	43	3	19454	50	TLN1,PTPN6,DISC1
1.834e-04	-8.60	BLNK (B cell linker)	protein interactions	29760	43	3	19454	50	GAB1,PTPN6,TLN1
1.964e-04	-8.54	HOXA10 (homeobox A10)	protein interactions	3206	44	3	19454	50	PTPN6,SPI1,RBPJ
1.967e-04	-8.53	regulation of neutrophil degranulation	biological process	GO:0043313	8	2	18204	49	ITGB2,SPI1
2.058e-04	-8.49	Integrin_alpha	pfam domains	PF00357	8	2	17795	49	ITGAV,ITGAL
2.097e-04	-8.47	cellular response to epidermal growth factor stimulus	biological process	GO:0071364	43	3	18204	49	PTPN12,DAB2,ZFP36L1
2.175e-04	-8.43	actin filament-based process	biological process	GO:0030029	616	8	18204	49	ARHGEF18,MYO1F,DOCK2,DNM2,TMSB4X,PREX1,TLN1,ARAP1
2.280e-04	-8.39	cell differentiation	biological process	GO:0030154	3645	21	18204	49	ITGAV,ARHGAP24,DAB2,ZFP36L1,SH2B3,RBM47,SPI1,PLXND1,DISC1,ITGB2,HCK,PREX1,ELF4,RXRA,RBPJ,PTPN6,DOCK2,AKAP13,LRMDA,DNM2,CD74
2.307e-04	-8.37	cellular developmental process	biological process	GO:0048869	3648	21	18204	49	AKAP13,LRMDA,DNM2,CD74,RXRA,RBPJ,PTPN6,DOCK2,DISC1,PLXND1,HCK,PREX1,ITGB2,ELF4,ITGAV,ARHGAP24,ZFP36L1,DAB2,SH2B3,RBM47,SPI1
2.349e-04	-8.36	GSK3B (glycogen synthase kinase 3 beta)	protein interactions	2932	831	9	19454	50	GAB1,DISC1,FKBP5,SPI1,DAB2,PTPN12,RBPJ,SEPTIN9,RXRA
2.383e-04	-8.34	vesicle	cellular component	GO:0031982	4141	22	19108	49	PTPN6,DISC1,CD74,HCK,ITGB2,ARHGAP45,ITM2B,DAB2,DNM2,CD68,STAB1,FKBP5,SLC9A7,DOCK2,ARHGEF18,ITGAL,TLN1,ITGAV,MCOLN2,EHD4,TMSB4X,ANTXR2
2.513e-04	-8.29	positive regulation of GTPase activity	biological process	GO:0043547	211	5	18204	49	ARHGAP24,PREX1,ARHGAP45,ARAP1,DOCK8
2.539e-04	-8.28	regulation of multicellular organismal process	biological process	GO:0051239	3113	19	18204	49	STAB1,SH2B3,SPI1,RBM47,ZFP36L1,BMP2K,DAB2,ELF4,DISC1,PLXND1,TMSB4X,RBPJ,BTG1,GAB1,PTPN6,RXRA,CD74,MCOLN2,DOCK8
2.649e-04	-8.24	SHC1 (SHC adaptor protein 1)	protein interactions	6464	350	6	19454	50	DNM2,ARAP1,PTPN12,PTPN6,GAB1,ITGAV
2.701e-04	-8.22	bounding membrane of organelle	cellular component	GO:0098588	2198	15	19108	49	ITGAV,ITGB2,ITGAL,SLC9A7,CD74,EHD4,WDFY3,ANTXR2,STAB1,MCOLN2,CD68,TFEB,DAB2,ITM2B,DNM2
2.734e-04	-8.20	response to epidermal growth factor	biological process	GO:0070849	47	3	18204	49	ZFP36L1,DAB2,PTPN12
2.864e-04	-8.16	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	37	16828	46	RXRA,DNM2,ITGB2,PREX1,SLC9A7,TLN1,ITGAV,TFEB,HCK,STAB1,RBM47,PTPN6,ARAP1,DOCK2,ZFP36L1,MYO1F,BTG1,ARHGAP24,DAB2,ARHGEF18,FKBP5,RBPJ,AKAP13,EHD4,ME1,RGL1,SPI1,ITGAL,CCND2,GAB1,PTPN12,MCOLN2,PLXND1,WDFY3,DOCK8,ELF4,BMP2K
2.978e-04	-8.12	regulation of actin cytoskeleton organization	biological process	GO:0032956	342	6	18204	49	PREX1,TMSB4X,HCK,ARAP1,AKAP13,ARHGEF18
3.050e-04	-8.10	CD247 (CD247 molecule)	protein interactions	919	51	3	19454	50	DOCK2,PTPN6,SH2B3
3.150e-04	-8.06	positive regulation of monocyte differentiation	biological process	GO:0045657	10	2	18204	49	ZFP36L1,CD74
3.177e-04	-8.05	defense response	biological process	GO:0006952	1431	12	18204	49	MCOLN2,CD74,ITGB2,HCK,RBPJ,STAB1,PTPN6,SPI1,PTGIR,CD68,TFEB,ITGAL
3.292e-04	-8.02	Nef and signal transduction	REACTOME pathways	R-HSA-164944	8	2	10285	36	HCK,DOCK2
3.292e-04	-8.02	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	21	16828	46	PTPN6,ELF4,DAB2,ARHGAP24,BTG1,AKAP13,RBPJ,ARHGEF18,FKBP5,BMP2K,RGL1,RXRA,SPI1,ITGB2,CCND2,PREX1,TFEB,HCK,PTPN12,ITGAV,GAB1
3.387e-04	-7.99	actin cytoskeleton	cellular component	GO:0015629	520	7	19108	49	DNM2,MYO1F,FYB1,PTPN12,HCK,SEPTIN9,AKAP13
3.447e-04	-7.97	intracellular signaling cassette	biological process	GO:0141124	837	9	18204	49	ITGAV,ARHGEF18,ZFP36L1,DOCK2,PTPN6,AKAP13,DOCK8,RGL1,MCOLN2
3.613e-04	-7.93	LCP2 (lymphocyte cytosolic protein 2)	protein interactions	3937	54	3	19454	50	PTPN6,HCK,FYB1
3.737e-04	-7.89	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	29	16828	46	DAB2,EHD4,AKAP13,FKBP5,ARHGEF18,RBPJ,DISC1,ANTXR2,ARAP1,MYO1F,DOCK2,PREX1,ITGAV,TFEB,STAB1,DNM2,RXRA,ITM2B,ITGB2,HEPHL1,ELF4,PLXND1,WDFY3,CCND2,PTPN12,RGL1,SH2B3,ITGAL,SPI1
3.784e-04	-7.88	protein binding	molecular function	GO:0005515	13983	47	18094	49	RXRA,PTPN12,HCK,ITGAL,EHD4,AKAP13,ARHGAP45,CD74,TMSB4X,PTPN6,ITM2B,DISC1,WDFY3,DAB2,RBM47,TFEB,GAB1,PREX1,ARAP1,FKBP5,ARHGEF18,PLXND1,RBPJ,TLN1,ME1,BMP2K,DOCK2,CCND2,ZFP36L1,DNM2,ARHGAP24,FYB1,MYO1F,SH2B3,ELF4,CD68,RGL1,DOCK8,SPI1,STAB1,SEPTIN9,MCOLN2,BTG1,ITGB2,ANTXR2,ITGAV,SLC9A7
3.801e-04	-7.88	regulation of biological quality	biological process	GO:0065008	2936	18	18204	49	DNM2,PTPN6,PTGIR,SLC9A7,DISC1,PLXND1,ARAP1,TLN1,PREX1,TMSB4X,HCK,ITGB2,SH2B3,RBM47,ITGAV,ARHGEF18,ZFP36L1,DAB2
3.844e-04	-7.86	positive regulation of chemokine (C-X-C motif) ligand 2 production	biological process	GO:2000343	11	2	18204	49	MCOLN2,CD74
3.844e-04	-7.86	pinocytosis	biological process	GO:0006907	11	2	18204	49	EHD4,DOCK2
3.844e-04	-7.86	regulation of dendritic cell antigen processing and presentation	biological process	GO:0002604	11	2	18204	49	CD68,CD74
3.868e-04	-7.86	DOCKER_Lobe_A	interpro domains	IPR046769	11	2	18521	50	DOCK8,DOCK2
3.868e-04	-7.86	DOCK	interpro domains	IPR026791	11	2	18521	50	DOCK2,DOCK8
3.868e-04	-7.86	DOCKER_Lobe_B	interpro domains	IPR046770	11	2	18521	50	DOCK8,DOCK2
3.868e-04	-7.86	DOCK_C_lobe_A	interpro domains	IPR043161	11	2	18521	50	DOCK8,DOCK2
3.868e-04	-7.86	C2_DOCK-type_domain	interpro domains	IPR027007	11	2	18521	50	DOCK2,DOCK8
3.868e-04	-7.86	DOCK_C_lobe_C	interpro domains	IPR043162	11	2	18521	50	DOCK2,DOCK8
3.868e-04	-7.86	DOCKER_dom	interpro domains	IPR027357	11	2	18521	50	DOCK2,DOCK8
3.868e-04	-7.86	DOCKER_Lobe_C	interpro domains	IPR046773	11	2	18521	50	DOCK8,DOCK2
3.868e-04	-7.86	regulation of B cell activation	biological process	GO:0050864	128	4	18204	49	CD74,PTPN6,SPI1,ZFP36L1
4.021e-04	-7.82	DHR-2_Lobe_A	pfam domains	PF06920	11	2	17795	49	DOCK8,DOCK2
4.021e-04	-7.82	DHR-2_Lobe_B	pfam domains	PF20422	11	2	17795	49	DOCK2,DOCK8
4.021e-04	-7.82	DOCK-C2	pfam domains	PF14429	11	2	17795	49	DOCK2,DOCK8
4.021e-04	-7.82	DHR-2_Lobe_C	pfam domains	PF20421	11	2	17795	49	DOCK2,DOCK8
4.102e-04	-7.80	lymphocyte proliferation	biological process	GO:0046651	130	4	18204	49	DOCK8,PTPN6,DOCK2,ELF4
4.152e-04	-7.79	mononuclear cell differentiation	biological process	GO:1903131	364	6	18204	49	PREX1,CD74,ZFP36L1,RBPJ,DOCK2,SPI1
4.207e-04	-7.77	protein complex involved in cell adhesion	cellular component	GO:0098636	57	3	19108	49	ITGAL,ITGAV,ITGB2
4.223e-04	-7.77	Formation of annular gap junctions	REACTOME pathways	R-HSA-196025	9	2	10285	36	DNM2,DAB2
4.291e-04	-7.75	ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)	protein interactions	25	248	5	19454	50	HCK,PTPN12,CCND2,PTPN6,BMP2K
4.432e-04	-7.72	regulation of multicellular organismal development	biological process	GO:2000026	1484	12	18204	49	BMP2K,ZFP36L1,STAB1,SPI1,PLXND1,DISC1,RXRA,RBPJ,GAB1,BTG1,PTPN6,CD74
4.498e-04	-7.71	positive regulation of catalytic activity	biological process	GO:0043085	868	9	18204	49	CD74,PREX1,TMSB4X,ITGB2,ARAP1,DOCK8,CCND2,ARHGAP24,ARHGAP45
4.601e-04	-7.68	mononuclear cell proliferation	biological process	GO:0032943	134	4	18204	49	DOCK2,PTPN6,ELF4,DOCK8
4.605e-04	-7.68	positive thymic T cell selection	biological process	GO:0045059	12	2	18204	49	DOCK2,CD74
4.605e-04	-7.68	negative thymic T cell selection	biological process	GO:0045060	12	2	18204	49	CD74,DOCK2
4.660e-04	-7.67	non-membrane spanning protein tyrosine phosphatase activity	molecular function	GO:0004726	12	2	18094	49	PTPN6,PTPN12
4.845e-04	-7.63	biological regulation	biological process	GO:0065007	12501	44	18204	49	ELF4,FYB1,TLN1,TMSB4X,PREX1,ME1,STAB1,PTPN12,SH2B3,ITGAV,ARHGAP45,BMP2K,ARHGAP24,CD74,MCOLN2,AKAP13,DOCK8,RBPJ,DOCK2,CD68,PTGIR,CCND2,EHD4,DISC1,PLXND1,SLC9A7,ARAP1,ITGB2,HCK,SPI1,SEPTIN9,ITM2B,RBM47,DAB2,ZFP36L1,ARHGEF18,ITGAL,TFEB,DNM2,RGL1,GAB1,BTG1,PTPN6,RXRA
4.990e-04	-7.60	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	22	16828	46	PLXND1,ANTXR2,RBM47,WDFY3,DOCK2,DOCK8,ARAP1,ELF4,AKAP13,RBPJ,CD74,ARHGEF18,DNM2,RGL1,SH2B3,RXRA,ITGAL,SPI1,PREX1,STAB1,MCOLN2,ITGAV
5.040e-04	-7.59	PRKCA (protein kinase C alpha)	protein interactions	5578	395	6	19454	50	PTPN12,AKAP13,PTPN6,PTGIR,ITGB2,SEPTIN9
5.074e-04	-7.59	SNW1 (SNW domain containing 1)	protein interactions	22938	731	8	19454	50	TLN1,DNM2,ARAP1,EHD4,RXRA,SEPTIN9,DOCK2,RBPJ
5.080e-04	-7.58	regulation of cell morphogenesis	biological process	GO:0022604	246	5	18204	49	ARAP1,PLXND1,ARHGEF18,ITGB2,HCK
5.220e-04	-7.56	negative regulation of biological process	biological process	GO:0048519	5737	27	18204	49	TMSB4X,ELF4,ARHGAP24,ITGAV,SH2B3,PTPN12,STAB1,DOCK8,CD74,CCND2,CD68,PTGIR,RBPJ,HCK,ITGB2,ARAP1,PLXND1,ZFP36L1,DAB2,ARHGEF18,RBM47,ITM2B,SPI1,DNM2,RXRA,PTPN6,BTG1
5.225e-04	-7.56	KDR (kinase insert domain receptor)	protein interactions	3791	145	4	19454	50	PTPN6,DNM2,PTPN12,PLXND1
5.267e-04	-7.55	Gap junction degradation	REACTOME pathways	R-HSA-190873	10	2	10285	36	DNM2,DAB2
5.281e-04	-7.55	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	38	16828	46	RGL1,SH2B3,ME1,ITGAL,SPI1,CCND2,MCOLN2,PTPN12,GAB1,PLXND1,WDFY3,DOCK8,ELF4,BMP2K,DNM2,ITGB2,TLN1,SLC9A7,PREX1,PTGIR,HCK,STAB1,TFEB,ITGAV,PTPN6,DISC1,RBM47,MYO1F,DOCK2,ARAP1,DAB2,ARHGAP24,BTG1,EHD4,AKAP13,RBPJ,FKBP5,ARHGEF18
5.355e-04	-7.53	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	38	16828	46	PREX1,PTGIR,SLC9A7,TLN1,TFEB,HCK,STAB1,ITGAV,DNM2,ITGB2,ARHGAP24,BTG1,DAB2,RBPJ,FKBP5,ARHGEF18,AKAP13,EHD4,RBM47,PTPN6,DISC1,MYO1F,DOCK2,ARAP1,CCND2,MCOLN2,PTPN12,GAB1,SH2B3,RGL1,ME1,SPI1,ITGAL,ELF4,BMP2K,PLXND1,DOCK8,WDFY3
5.382e-04	-7.53	human chr4q21.21	chromosome location	human chr4q21.21	18	2	26134	50	BMP2K,ANTXR2
5.432e-04	-7.52	negative regulation of platelet-derived growth factor receptor signaling pathway	biological process	GO:0010642	13	2	18204	49	PTPN12,PTGIR
5.432e-04	-7.52	negative T cell selection	biological process	GO:0043383	13	2	18204	49	DOCK2,CD74
5.507e-04	-7.50	cytokine-mediated signaling pathway	biological process	GO:0019221	384	6	18204	49	TMSB4X,HCK,CD74,SH2B3,SPI1,PTPN6
5.507e-04	-7.50	regulation of actin filament-based process	biological process	GO:0032970	384	6	18204	49	AKAP13,ARAP1,TMSB4X,PREX1,HCK,ARHGEF18
5.572e-04	-7.49	regulation of anatomical structure morphogenesis	biological process	GO:0022603	894	9	18204	49	GAB1,BTG1,STAB1,ARHGEF18,ITGB2,HCK,ARAP1,PLXND1,DISC1
5.776e-04	-7.46	ITGAL (integrin subunit alpha L)	protein interactions	3683	14	2	19454	50	ITGAL,ITGB2
5.814e-04	-7.45	-	gene3d domains	1.25.40.410	11	2	14470	48	DOCK2,DOCK8
5.814e-04	-7.45	-	gene3d domains	1.20.58.740	11	2	14470	48	DOCK8,DOCK2
5.815e-04	-7.45	regulation of supramolecular fiber organization	biological process	GO:1902903	388	6	18204	49	ARHGEF18,HCK,PREX1,TMSB4X,AKAP13,ARAP1
5.877e-04	-7.44	mesothelioma	COSMIC cancer mutations	mesothelioma	4477	23	16828	46	ITGB2,PREX1,SLC9A7,TLN1,TFEB,HCK,ITGAV,PTPN6,ARHGAP24,BTG1,DAB2,RBPJ,FKBP5,ARHGEF18,AKAP13,RGL1,SH2B3,SPI1,CCND2,PTPN12,GAB1,ELF4,BMP2K
6.244e-04	-7.38	pleura-mesothelioma	COSMIC cancer mutations	pleura-mesothelioma	4189	22	16828	46	ELF4,BMP2K,CCND2,PTPN12,GAB1,RGL1,SPI1,DAB2,ARHGAP24,BTG1,AKAP13,RBPJ,FKBP5,ARHGEF18,PTPN6,TLN1,SLC9A7,PREX1,TFEB,HCK,ITGAV,ITGB2
6.327e-04	-7.37	alpha-beta T cell proliferation	biological process	GO:0046633	14	2	18204	49	DOCK2,ELF4
6.327e-04	-7.37	immunological synapse formation	biological process	GO:0001771	14	2	18204	49	DOCK2,DOCK8
6.350e-04	-7.36	positive regulation of response to stimulus	biological process	GO:0048584	2266	15	18204	49	SPI1,RBM47,BMP2K,DAB2,ITGAV,FYB1,TMSB4X,ITGB2,HCK,DISC1,PTPN6,RBPJ,RXRA,CD74,AKAP13
6.366e-04	-7.36	G_DYNAMIN_dom	interpro domains	IPR030381	14	2	18521	50	EHD4,DNM2
6.518e-04	-7.34	cell population proliferation	biological process	GO:0008283	726	8	18204	49	DISC1,DOCK8,ELF4,ZFP36L1,RBPJ,DOCK2,BTG1,PTPN6
6.581e-04	-7.33	protein-containing complex binding	molecular function	GO:0044877	1772	13	18094	49	CD74,BMP2K,STAB1,DOCK2,DISC1,ITGAL,RBPJ,ITGAV,SPI1,TLN1,ITGB2,FYB1,MYO1F
6.654e-04	-7.32	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	50	DISC1,DNM2
6.835e-04	-7.29	ERBB2 (erb-b2 receptor tyrosine kinase 2)	protein interactions	2064	583	7	19454	50	SH2B3,CCND2,HCK,PTPN6,TLN1,ITGAV,GAB1
6.956e-04	-7.27	inflammatory response	biological process	GO:0006954	559	7	18204	49	HCK,ITGB2,RBPJ,STAB1,CD68,PTGIR,ITGAL
7.004e-04	-7.26	cellular response to cytokine stimulus	biological process	GO:0071345	734	8	18204	49	ZFP36L1,PTPN6,SPI1,SH2B3,HCK,TMSB4X,DOCK8,CD74
7.119e-04	-7.25	T cell differentiation in thymus	biological process	GO:0033077	65	3	18204	49	CD74,DOCK2,ZFP36L1
7.156e-04	-7.24	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	23	16828	46	HCK,TFEB,ITGAV,PREX1,SLC9A7,TLN1,ITGB2,RBPJ,ARHGEF18,FKBP5,AKAP13,ARHGAP24,BTG1,DAB2,DOCK2,PTPN6,PTPN12,GAB1,CCND2,SPI1,RGL1,BMP2K,ELF4
7.156e-04	-7.24	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	23	16828	46	SPI1,RGL1,GAB1,PTPN12,CCND2,BMP2K,ELF4,ITGB2,ITGAV,TFEB,HCK,PREX1,SLC9A7,TLN1,DOCK2,PTPN6,FKBP5,ARHGEF18,RBPJ,AKAP13,BTG1,ARHGAP24,DAB2
7.188e-04	-7.24	RhoGAP_dom	interpro domains	IPR000198	65	3	18521	50	ARHGAP45,ARHGAP24,ARAP1
7.284e-04	-7.22	cell adhesion molecule binding	molecular function	GO:0050839	560	7	18094	49	ITGB2,ITGAL,SEPTIN9,PTPN6,ITGAV,EHD4,TLN1
7.333e-04	-7.22	Dynamin_N	interpro domains	IPR045063	15	2	18521	50	EHD4,DNM2
7.444e-04	-7.20	neutrophil migration	biological process	GO:1990266	66	3	18204	49	ITGB2,PREX1,MCOLN2
7.503e-04	-7.20	DOCKER	prosite domains	PS51651	11	2	12186	46	DOCK8,DOCK2
7.503e-04	-7.20	C2_DOCK	prosite domains	PS51650	11	2	12186	46	DOCK2,DOCK8
7.575e-04	-7.19	leukocyte proliferation	biological process	GO:0070661	153	4	18204	49	DOCK8,PTPN6,DOCK2,ELF4
7.592e-04	-7.18	ESM1 (endothelial cell specific molecule 1)	protein interactions	11082	16	2	19454	50	ITGB2,ITGAL
7.601e-04	-7.18	RhoGAP	pfam domains	PF00620	65	3	17795	49	ARAP1,ARHGAP45,ARHGAP24
7.611e-04	-7.18	regulation of actin filament organization	biological process	GO:0110053	269	5	18204	49	ARAP1,HCK,ARHGEF18,PREX1,TMSB4X
7.623e-04	-7.18	Dynamin_N	pfam domains	PF00350	15	2	17795	49	EHD4,DNM2
7.691e-04	-7.17	PECAM1 interactions	REACTOME pathways	R-HSA-210990	12	2	10285	36	PTPN6,ITGAV
7.747e-04	-7.16	ITGB3 (integrin subunit beta 3)	protein interactions	3690	70	3	19454	50	ITGAV,TLN1,DAB2
7.851e-04	-7.15	lung-carcinoma	COSMIC cancer mutations	lung-carcinoma	4255	22	16828	46	ITGB2,SPI1,RGL1,GAB1,ITGAV,HCK,PTPN12,TFEB,PREX1,CCND2,SLC9A7,TLN1,PTPN6,ARHGEF18,BMP2K,FKBP5,RBPJ,AKAP13,BTG1,ARHGAP24,DAB2,ELF4
7.852e-04	-7.15	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	25	16828	46	PREX1,TLN1,SLC9A7,ITGAV,TFEB,HCK,ITGB2,BTG1,ARHGAP24,DAB2,ARHGEF18,FKBP5,RBPJ,AKAP13,PTPN6,ARAP1,CCND2,GAB1,PTPN12,ME1,RGL1,SPI1,ELF4,BMP2K,PLXND1
7.852e-04	-7.15	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	25	16828	46	GAB1,PTPN12,CCND2,SPI1,ME1,RGL1,BMP2K,ELF4,PLXND1,ITGAV,TFEB,HCK,SLC9A7,TLN1,PREX1,ITGB2,AKAP13,ARHGEF18,FKBP5,RBPJ,DAB2,BTG1,ARHGAP24,ARAP1,PTPN6
7.952e-04	-7.14	myeloid leukocyte activation	biological process	GO:0002274	155	4	18204	49	RBPJ,DOCK2,ITGB2,PREX1
8.050e-04	-7.12	molecular adaptor activity	molecular function	GO:0060090	1138	10	18094	49	AKAP13,RBM47,SH2B3,FKBP5,SPI1,BTG1,DAB2,GAB1,SEPTIN9,DISC1
8.315e-04	-7.09	wound healing, spreading of epidermal cells	biological process	GO:0035313	16	2	18204	49	ITGAV,ARHGAP24
8.356e-04	-7.09	GTPase activator activity	molecular function	GO:0005096	273	5	18094	49	DOCK2,ARAP1,PREX1,ARHGAP45,ARHGAP24
8.366e-04	-7.09	Integrin_alpha_Ig-like_1	interpro domains	IPR013649	16	2	18521	50	ITGAL,ITGAV
8.366e-04	-7.09	Integrin_alpha_C_CS	interpro domains	IPR018184	16	2	18521	50	ITGAL,ITGAV
8.410e-04	-7.08	ITGB2 (integrin subunit beta 2)	protein interactions	3689	72	3	19454	50	ITGB2,TLN1,ITGAL
8.566e-04	-7.06	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	156	4	16828	46	SPI1,HCK,BTG1,ARHGAP24
8.696e-04	-7.05	Integrin_A_Ig_1	pfam domains	PF08441	16	2	17795	49	ITGAV,ITGAL
8.735e-04	-7.04	integrin binding	molecular function	GO:0005178	158	4	18094	49	ITGAV,ITGB2,ITGAL,TLN1
8.753e-04	-7.04	ATG9A (autophagy related 9A)	protein interactions	79065	439	6	19454	50	DAB2,DISC1,BMP2K,PTGIR,WDFY3,EHD4
8.822e-04	-7.03	actin filament organization	biological process	GO:0007015	278	5	18204	49	ARAP1,MYO1F,PREX1,TMSB4X,DNM2
8.923e-04	-7.02	DH-domain	interpro domains	IPR000219	70	3	18521	50	ARHGEF18,PREX1,AKAP13
9.003e-04	-7.01	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	7	19454	50	ME1,BMP2K,GAB1,ITM2B,RXRA,SEPTIN9,DNM2
9.069e-04	-7.01	RALBP1 (ralA binding protein 1)	protein interactions	10928	168	4	19454	50	BMP2K,SEPTIN9,HCK,RBM47
9.069e-04	-7.01	Signal regulatory protein (SIRP) family interactions	REACTOME pathways	R-HSA-391160	13	2	10285	36	FYB1,PTPN6
9.299e-04	-6.98	DBL_dom_sf	interpro domains	IPR035899	71	3	18521	50	PREX1,ARHGEF18,AKAP13
9.350e-04	-6.97	leukocyte differentiation	biological process	GO:0002521	425	6	18204	49	DOCK2,SPI1,RBPJ,ZFP36L1,CD74,PREX1
9.434e-04	-6.97	RhoGEF	pfam domains	PF00621	70	3	17795	49	PREX1,ARHGEF18,AKAP13
9.592e-04	-6.95	receptor-mediated endocytosis	biological process	GO:0006898	163	4	18204	49	STAB1,ITGB2,DNM2,DAB2
9.738e-04	-6.93	positive regulation of cell migration	biological process	GO:0030335	592	7	18204	49	GAB1,ITGAV,DAB2,CD74,DOCK8,PREX1,TMSB4X
9.772e-04	-6.93	regulation of transport	biological process	GO:0051049	1621	12	18204	49	SPI1,BMP2K,DAB2,ITGAV,EHD4,ITGB2,TMSB4X,HCK,DOCK2,PTPN6,RXRA,CD74
1.016e-03	-6.89	cargo receptor activity	molecular function	GO:0038024	73	3	18094	49	ITGB2,STAB1,DAB2
1.033e-03	-6.88	NME2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	4831	174	4	19454	50	AKAP13,ARHGAP24,DOCK8,PREX1
1.040e-03	-6.87	cell junction	cellular component	GO:0030054	2224	14	19108	49	FYB1,DAB2,ARHGAP24,DNM2,GAB1,ITGAV,TLN1,PTPN12,ITGB2,HCK,PTPN6,DISC1,PLXND1,ARHGEF18
1.043e-03	-6.87	negative regulation of intracellular signal transduction	biological process	GO:1902532	599	7	18204	49	CD74,TMSB4X,SH2B3,SPI1,PTPN6,DAB2,ARHGAP24
1.049e-03	-6.86	CDC5L (cell division cycle 5 like)	protein interactions	988	817	8	19454	50	PTPN6,TLN1,DOCK8,DNM2,EHD4,SEPTIN9,STAB1,DISC1
1.053e-03	-6.86	Integrin-mediated Cell Adhesion	WikiPathways	WP185	103	4	5310	24	TLN1,ITGAL,ITGAV,ITGB2
1.054e-03	-6.85	blood vessel morphogenesis	biological process	GO:0048514	435	6	18204	49	PLXND1,RBPJ,GAB1,ITGAV,ZFP36L1,ARHGAP24
1.055e-03	-6.85	WARS1 (tryptophanyl-tRNA synthetase 1)	protein interactions	7453	175	4	19454	50	PTPN12,EHD4,DNM2,SEPTIN9
1.056e-03	-6.85	regulation of clathrin-dependent endocytosis	biological process	GO:2000369	18	2	18204	49	DAB2,BMP2K
1.063e-03	-6.85	Integrin_alpha	interpro domains	IPR000413	18	2	18521	50	ITGAL,ITGAV
1.063e-03	-6.85	Integrin_alpha_Ig-like_2	interpro domains	IPR048285	18	2	18521	50	ITGAL,ITGAV
1.071e-03	-6.84	response to biotic stimulus	biological process	GO:0009607	1408	11	18204	49	PTGIR,CD68,PTPN6,RBPJ,FKBP5,MCOLN2,CD74,TFEB,SPI1,STAB1,HCK
1.074e-03	-6.84	SH3KBP1 (SH3 domain containing kinase binding protein 1)	protein interactions	30011	304	5	19454	50	SEPTIN9,ARAP1,DAB2,DNM2,HCK
1.077e-03	-6.83	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	2	19454	50	RGL1,ARHGAP24
1.078e-03	-6.83	Paxillin-dependent events mediated by a4b1	Pathway Interaction DB	a4b1_paxdep_pathway	19	3	2226	25	ITGB2,ITGAL,TLN1
1.097e-03	-6.82	positive regulation of molecular function	biological process	GO:0044093	1192	10	18204	49	CD74,ITGB2,TMSB4X,PREX1,DOCK8,ARAP1,RXRA,ARHGAP24,CCND2,ARHGAP45
1.105e-03	-6.81	Integrin_A_Ig_2	pfam domains	PF20805	18	2	17795	49	ITGAV,ITGAL
1.121e-03	-6.79	positive regulation of immune system process	biological process	GO:0002684	986	9	18204	49	HCK,ITGB2,DOCK8,FYB1,CD74,ZFP36L1,SPI1,PTPN6,RBM47
1.124e-03	-6.79	ERBB4 (erb-b2 receptor tyrosine kinase 4)	protein interactions	2066	178	4	19454	50	PTPN6,PTPN12,HCK,SH2B3
1.166e-03	-6.75	lung-carcinoma-undifferentiated_carcinoma	COSMIC cancer mutations	lung-carcinoma-undifferentiated_carcinoma	1408	11	16828	46	PTPN6,RBPJ,ELF4,BTG1,ITGAL,RGL1,TFEB,GAB1,CCND2,TLN1,PTGIR
1.175e-03	-6.75	NRAGE signals death through JNK	REACTOME pathways	R-HSA-193648	60	3	10285	36	AKAP13,PREX1,ARHGEF18
1.184e-03	-6.74	THRB (thyroid hormone receptor beta)	protein interactions	7068	81	3	19454	50	RXRA,ARHGAP24,BTG1
1.186e-03	-6.74	Int_alpha_beta-p	interpro domains	IPR013519	19	2	18521	50	ITGAV,ITGAL
1.206e-03	-6.72	ILK (integrin linked kinase)	protein interactions	3611	312	5	19454	50	ITGB2,FKBP5,SH2B3,ITGAV,TMSB4X
1.221e-03	-6.71	human chr5p13.1	chromosome location	human chr5p13.1	27	2	26134	50	FYB1,DAB2
1.232e-03	-6.70	G_DYNAMIN_2	prosite domains	PS51718	14	2	12186	46	DNM2,EHD4
1.233e-03	-6.70	FG-GAP	pfam domains	PF01839	19	2	17795	49	ITGAV,ITGAL
1.236e-03	-6.70	undifferentiated_carcinoma	COSMIC cancer mutations	undifferentiated_carcinoma	1418	11	16828	46	RBPJ,TFEB,GAB1,BTG1,PTGIR,ELF4,TLN1,CCND2,ITGAL,RGL1,PTPN6
1.238e-03	-6.69	intracellular anatomical structure	cellular component	GO:0005622	15205	47	19108	49	PREX1,DOCK8,FYB1,MCOLN2,ARHGAP24,ELF4,TLN1,ITGAV,PTGIR,ITGAL,DOCK2,RBM47,SEPTIN9,BMP2K,STAB1,CD68,DAB2,RBPJ,DNM2,PTPN12,HCK,DISC1,CD74,TMSB4X,EHD4,WDFY3,ANTXR2,SPI1,SH2B3,RXRA,ZFP36L1,CCND2,ARHGEF18,SLC9A7,FKBP5,AKAP13,RGL1,GAB1,MYO1F,TFEB,ITM2B,ARHGAP45,ARAP1,ITGB2,PTPN6,BTG1,ME1
1.240e-03	-6.69	HSF2BP (heat shock transcription factor 2 binding protein)	protein interactions	11077	314	5	19454	50	HCK,DOCK8,SEPTIN9,ARHGAP45,TMSB4X
1.245e-03	-6.69	GSN (gelsolin)	protein interactions	2934	183	4	19454	50	ARHGAP24,DISC1,CCND2,PTPN12
1.261e-03	-6.68	positive regulation of cell motility	biological process	GO:2000147	619	7	18204	49	CD74,DOCK8,TMSB4X,PREX1,GAB1,ITGAV,DAB2
1.289e-03	-6.65	Neutrophil degranulation	REACTOME pathways	R-HSA-6798695	487	7	10285	36	PTPN6,ARHGAP45,CD68,DOCK2,ITGB2,ITGAL,ITGAV
1.294e-03	-6.65	LGALS1 (galectin 1)	protein interactions	3956	317	5	19454	50	FKBP5,HCK,PLXND1,ITGAV,CD68
1.307e-03	-6.64	regulation of monocyte differentiation	biological process	GO:0045655	20	2	18204	49	CD74,ZFP36L1
1.307e-03	-6.64	regulation of chemokine (C-X-C motif) ligand 2 production	biological process	GO:2000341	20	2	18204	49	MCOLN2,CD74
1.307e-03	-6.64	regulation of antigen processing and presentation	biological process	GO:0002577	20	2	18204	49	CD68,CD74
1.334e-03	-6.62	regulation of cellular process	biological process	GO:0050794	11468	41	18204	49	PTGIR,CCND2,RBPJ,DOCK2,DOCK8,AKAP13,MCOLN2,CD74,ARHGAP45,ITGAV,ARHGAP24,BMP2K,PTPN12,SH2B3,ME1,PREX1,TLN1,TMSB4X,ELF4,FYB1,RXRA,PTPN6,BTG1,GAB1,RGL1,DNM2,TFEB,ARHGEF18,DAB2,ITGAL,ZFP36L1,RBM47,SEPTIN9,ITM2B,SPI1,ARAP1,DISC1,PLXND1,ITGB2,HCK,EHD4
1.354e-03	-6.60	Rho GTPase activation protein	gene3d domains	1.10.555.10	66	3	14470	48	ARAP1,ARHGAP24,ARHGAP45
1.386e-03	-6.58	Regulation of KIT signaling	REACTOME pathways	R-HSA-1433559	16	2	10285	36	PTPN6,SH2B3
1.395e-03	-6.58	vacuole	cellular component	GO:0005773	857	8	19108	49	TFEB,CD68,MCOLN2,CD74,DAB2,WDFY3,ARHGAP45,HCK
1.398e-03	-6.57	endoderm development	biological process	GO:0007492	82	3	18204	49	ITGAV,ZFP36L1,ITGB2
1.407e-03	-6.57	WAS (WASP actin nucleation promoting factor)	protein interactions	7454	86	3	19454	50	FYB1,HCK,PTPN12
1.420e-03	-6.56	ntegrin, alpha v. Chain A, domain 4	gene3d domains	2.60.40.1530	17	2	14470	48	ITGAV,ITGAL
1.432e-03	-6.55	negative regulation of cell adhesion	biological process	GO:0007162	310	5	18204	49	SH2B3,CD74,PTPN6,SPI1,PLXND1
1.435e-03	-6.55	positive regulation of locomotion	biological process	GO:0040017	633	7	18204	49	ITGAV,DAB2,GAB1,DOCK8,TMSB4X,PREX1,CD74
1.442e-03	-6.54	regulation of cytokine-mediated signaling pathway	biological process	GO:0001959	182	4	18204	49	CD74,SH2B3,RBM47,PTPN6
1.443e-03	-6.54	plasma membrane signaling receptor complex	cellular component	GO:0098802	191	4	19108	49	ITGAL,ITGB2,ITGAV,PTPN6
1.443e-03	-6.54	positive regulation of myeloid leukocyte mediated immunity	biological process	GO:0002888	21	2	18204	49	SPI1,ITGB2
1.443e-03	-6.54	thymic T cell selection	biological process	GO:0045061	21	2	18204	49	CD74,DOCK2
1.447e-03	-6.54	FCGR2B (Fc gamma receptor IIb)	protein interactions	2213	22	2	19454	50	PTPN6,GAB1
1.452e-03	-6.54	FG-GAP	interpro domains	IPR013517	21	2	18521	50	ITGAV,ITGAL
1.455e-03	-6.53	FGR (FGR proto-oncogene, Src family tyrosine kinase)	protein interactions	2268	87	3	19454	50	HCK,DAB2,FKBP5
1.455e-03	-6.53	PLCG2 (phospholipase C gamma 2)	protein interactions	5336	87	3	19454	50	PTPN6,HCK,GAB1
1.460e-03	-6.53	opsonin binding	molecular function	GO:0001846	21	2	18094	49	ITGAV,ITGB2
1.472e-03	-6.52	secretory vesicle	cellular component	GO:0099503	1076	9	19108	49	DOCK2,DISC1,PTPN6,CD68,ITGAL,ITGB2,ITGAV,ARHGAP45,TMSB4X
1.489e-03	-6.51	localization	biological process	GO:0051179	4474	22	18204	49	FYB1,EHD4,TMSB4X,ITGB2,HCK,DISC1,SLC9A7,SEPTIN9,STAB1,TFEB,ITGAL,ARHGEF18,DAB2,ZFP36L1,ITGAV,MCOLN2,CD74,DNM2,HEPHL1,DOCK2,CD68,MYO1F
1.508e-03	-6.50	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	17	16828	46	RXRA,RGL1,ITGAL,CCND2,TLN1,PTGIR,GAB1,ITGAV,TFEB,PLXND1,PTPN6,RBM47,WDFY3,ELF4,BTG1,ARHGAP24,RBPJ
1.508e-03	-6.50	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	17	16828	46	RBPJ,ELF4,BTG1,ARHGAP24,WDFY3,PLXND1,PTPN6,RBM47,ITGAV,GAB1,TFEB,TLN1,CCND2,PTGIR,ITGAL,RXRA,RGL1
1.515e-03	-6.49	vacuolar membrane	cellular component	GO:0005774	490	6	19108	49	WDFY3,CD74,DAB2,TFEB,CD68,MCOLN2
1.528e-03	-6.48	positive regulation of immune response	biological process	GO:0050778	640	7	18204	49	HCK,ITGB2,CD74,FYB1,SPI1,RBM47,PTPN6
1.551e-03	-6.47	protein localization	biological process	GO:0008104	1954	13	18204	49	CD68,DNM2,CD74,MCOLN2,DAB2,ARHGEF18,ITGAL,SEPTIN9,TMSB4X,ITGB2,DISC1,FYB1,EHD4
1.587e-03	-6.45	MAPK1 (mitogen-activated protein kinase 1)	protein interactions	5594	493	6	19454	50	ITGAV,GAB1,ME1,RXRA,ARHGAP45,PTPN12
1.594e-03	-6.44	Bicelle-embedded integrin alpha(iib) transmembrane segment	gene3d domains	1.20.5.930	18	2	14470	48	ITGAL,ITGAV
1.594e-03	-6.44	Integrin domains. Chain A, domain 2	gene3d domains	2.60.40.1460	18	2	14470	48	ITGAV,ITGAL
1.595e-03	-6.44	response to cytokine	biological process	GO:0034097	834	8	18204	49	SPI1,PTPN6,SH2B3,ZFP36L1,CD74,TMSB4X,HCK,DOCK8
1.610e-03	-6.43	cellular macromolecule localization	biological process	GO:0070727	1962	13	18204	49	DNM2,CD74,MCOLN2,CD68,ITGB2,TMSB4X,DISC1,FYB1,EHD4,ITGAL,DAB2,ARHGEF18,SEPTIN9
1.617e-03	-6.43	INTEGRIN_ALPHA	prosite domains	PS00242	16	2	12186	46	ITGAL,ITGAV
1.632e-03	-6.42	PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3)	protein interactions	8503	197	4	19454	50	DISC1,GAB1,WDFY3,HCK
1.640e-03	-6.41	lymph_node	COSMIC cancer mutations	lymph_node	1703	12	16828	46	DOCK2,WDFY3,ZFP36L1,ELF4,ARHGAP24,BTG1,AKAP13,CD74,DNM2,SPI1,HCK,ITGAV
1.643e-03	-6.41	specific granule membrane	cellular component	GO:0035579	91	3	19108	49	ITGAL,ITGAV,ITGB2
1.655e-03	-6.40	SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1)	protein interactions	6654	91	3	19454	50	HCK,PTPN6,GAB1
1.657e-03	-6.40	embryonic placenta development	biological process	GO:0001892	87	3	18204	49	ZFP36L1,TFEB,RBPJ
1.671e-03	-6.39	Dbl homology (DH) domain	gene3d domains	1.20.900.10	71	3	14470	48	PREX1,ARHGEF18,AKAP13
1.688e-03	-6.38	Integrin cell surface interactions	REACTOME pathways	R-HSA-216083	68	3	10285	36	ITGAV,ITGAL,ITGB2
1.708e-03	-6.37	LIMS1 (LIM zinc finger domain containing 1)	protein interactions	3987	92	3	19454	50	BMP2K,TMSB4X,FKBP5
1.713e-03	-6.37	NRAS (NRAS proto-oncogene, GTPase)	protein interactions	4893	683	7	19454	50	ITM2B,GAB1,FYB1,RGL1,DOCK8,PREX1,SEPTIN9
1.713e-03	-6.37	AURKA (aurora kinase A)	protein interactions	6790	683	7	19454	50	DAB2,FKBP5,SPI1,ARHGAP45,TMSB4X,CCND2,DOCK8
1.725e-03	-6.36	SEPTIN7 (septin 7)	protein interactions	989	200	4	19454	50	CCND2,DOCK8,TLN1,SEPTIN9
1.732e-03	-6.36	megakaryocyte development	biological process	GO:0035855	23	2	18204	49	PTPN6,SH2B3
1.743e-03	-6.35	Integrin_alpha_N	interpro domains	IPR028994	23	2	18521	50	ITGAV,ITGAL
1.752e-03	-6.35	response to organic substance	biological process	GO:0010033	2498	15	18204	49	ZFP36L1,DAB2,SH2B3,SPI1,HCK,TMSB4X,ITGB2,ME1,PTGIR,CD68,RXRA,GAB1,PTPN6,DOCK8,CD74
1.775e-03	-6.33	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	42	16828	46	PTGIR,PREX1,SLC9A7,ITGAV,TFEB,STAB1,HCK,RXRA,DNM2,ITM2B,ITGB2,BTG1,ARHGAP24,DAB2,FKBP5,ARHGEF18,CD74,EHD4,AKAP13,RBM47,ANTXR2,PTPN6,ARAP1,DOCK2,MYO1F,ZFP36L1,CCND2,GAB1,MCOLN2,PTPN12,ME1,RGL1,SH2B3,SPI1,ITGAL,HEPHL1,ELF4,BMP2K,TMSB4X,PLXND1,WDFY3,DOCK8
1.800e-03	-6.32	amyloid-beta binding	molecular function	GO:0001540	89	3	18094	49	CD74,ITM2B,ITGB2
1.809e-03	-6.31	signaling receptor binding	molecular function	GO:0005102	1493	11	18094	49	HCK,ITGAL,DAB2,DOCK2,CD74,ITGB2,FYB1,ARAP1,SH2B3,ITGAV,TLN1
1.822e-03	-6.31	regulation of response to cytokine stimulus	biological process	GO:0060759	194	4	18204	49	CD74,SH2B3,RBM47,PTPN6
1.829e-03	-6.30	RHOU (ras homolog family member U)	protein interactions	58480	507	6	19454	50	ITGAV,GAB1,DAB2,ITM2B,DNM2,EHD4
1.861e-03	-6.29	secretory granule	cellular component	GO:0030141	897	8	19108	49	CD68,ITGAL,DOCK2,PTPN6,TMSB4X,ARHGAP45,ITGB2,ITGAV
1.867e-03	-6.28	RHOGAP	prosite domains	PS50238	65	3	12186	46	ARAP1,ARHGAP24,ARHGAP45
1.870e-03	-6.28	lower_third	COSMIC cancer mutations	lower_third	7961	32	16828	46	HEPHL1,ELF4,WDFY3,PLXND1,PTPN12,CCND2,SPI1,ITGAL,RGL1,SH2B3,FKBP5,ARHGEF18,RBPJ,EHD4,AKAP13,ARHGAP24,DAB2,ARAP1,DOCK2,MYO1F,ANTXR2,DISC1,ITGAV,STAB1,TFEB,PREX1,SLC9A7,TLN1,ITM2B,ITGB2,RXRA,DNM2
1.886e-03	-6.27	myeloid dendritic cell activation	biological process	GO:0001773	24	2	18204	49	DOCK2,RBPJ
1.886e-03	-6.27	regulation of platelet-derived growth factor receptor signaling pathway	biological process	GO:0010640	24	2	18204	49	PTPN12,PTGIR
1.902e-03	-6.26	recycling endosome	cellular component	GO:0055037	206	4	19108	49	MCOLN2,EHD4,SLC9A7,DNM2
1.910e-03	-6.26	vesicle-mediated transport	biological process	GO:0016192	1283	10	18204	49	EHD4,ITGB2,DNM2,HCK,DOCK2,STAB1,ITGAL,DAB2,MYO1F,ITGAV
1.913e-03	-6.26	human chr4q21.23-q21.3	chromosome location	human chr4q21.23-q21.3	1	1	26134	50	ARHGAP24
1.913e-03	-6.26	human chr10q22.2-q22.3	chromosome location	human chr10q22.2-q22.3	1	1	26134	50	LRMDA
1.913e-03	-6.26	human chrXp11.3\|Xp11.3	chromosome location	human chrXp11.3\|Xp11.3	1	1	26134	50	SLC9A7
1.918e-03	-6.26	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	7	18204	49	PREX1,PLXND1,DISC1,ARAP1,DAB2,ARHGAP24,SEPTIN9
1.949e-03	-6.24	endocytic vesicle	cellular component	GO:0030139	349	5	19108	49	EHD4,STAB1,DNM2,CD74,ITGAV
1.969e-03	-6.23	regulation of apoptotic process	biological process	GO:0042981	1518	11	18204	49	DAB2,ZFP36L1,ITGAV,HCK,PLXND1,CCND2,PTPN6,BTG1,DNM2,DOCK8,CD74
1.993e-03	-6.22	negative regulation of response to stimulus	biological process	GO:0048585	1760	12	18204	49	CD74,PTPN6,PTGIR,ELF4,HCK,TMSB4X,SPI1,SH2B3,PTPN12,DAB2,ARHGAP24,ITGAV
2.023e-03	-6.20	POU2F2 (POU class 2 homeobox 2)	protein interactions	5452	26	2	19454	50	ARHGAP24,RXRA
2.025e-03	-6.20	lipid binding	molecular function	GO:0008289	861	8	18094	49	TLN1,DNM2,ARAP1,FYB1,WDFY3,PREX1,HCK,RXRA
2.025e-03	-6.20	GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase)	protein interactions	2618	209	4	19454	50	FKBP5,TLN1,ARHGEF18,ARHGAP24
2.052e-03	-6.19	INTEGRINA	prints domains	PR01185	18	2	5227	20	ITGAV,ITGAL
2.073e-03	-6.18	negative regulation of inflammatory response	biological process	GO:0050728	201	4	18204	49	TMSB4X,HCK,PTPN6,ELF4
2.097e-03	-6.17	CRKL (CRK like proto-oncogene, adaptor protein)	protein interactions	1399	211	4	19454	50	HCK,DOCK2,DNM2,GAB1
2.109e-03	-6.16	nodular	COSMIC cancer mutations	nodular	1515	11	16828	46	ITGB2,PTPN12,STAB1,TFEB,DOCK2,DOCK8,WDFY3,DISC1,RBM47,AKAP13,FKBP5
2.125e-03	-6.15	cell projection membrane	cellular component	GO:0031253	356	5	19108	49	TLN1,ITGAV,PLXND1,DOCK8,ARHGAP45
2.141e-03	-6.15	regulation of cell-cell adhesion	biological process	GO:0022407	500	6	18204	49	DOCK8,ITGB2,SH2B3,CD74,PTPN6,SPI1
2.149e-03	-6.14	negative regulation of cell-cell adhesion	biological process	GO:0022408	203	4	18204	49	CD74,SH2B3,SPI1,PTPN6
2.161e-03	-6.14	cell projection	cellular component	GO:0042995	2398	14	19108	49	DNM2,ARHGAP24,MYO1F,PREX1,DOCK8,SEPTIN9,WDFY3,DISC1,PLXND1,HCK,PTPN12,TLN1,ITGAV,ARHGAP45
2.168e-03	-6.13	REPS1 (RALBP1 associated Eps domain containing 1)	protein interactions	85021	100	3	19454	50	RXRA,BMP2K,DAB2
2.168e-03	-6.13	HRAS (HRas proto-oncogene, GTPase)	protein interactions	3265	712	7	19454	50	ARHGEF18,ITM2B,GAB1,RGL1,DOCK8,DNM2,SEPTIN9
2.174e-03	-6.13	regulation of localization	biological process	GO:0032879	2028	13	18204	49	TMSB4X,HCK,ITGB2,EHD4,ITGAV,ZFP36L1,DAB2,BMP2K,SPI1,CD74,RXRA,DOCK2,PTPN6
2.176e-03	-6.13	response to bacterium	biological process	GO:0009617	681	7	18204	49	HCK,FKBP5,CD68,PTGIR,TFEB,STAB1,RBPJ
2.181e-03	-6.13	OLIG1 (oligodendrocyte transcription factor 1)	protein interactions	116448	27	2	19454	50	PTPN6,HCK
2.181e-03	-6.13	ICAM3 (intercellular adhesion molecule 3)	protein interactions	3385	27	2	19454	50	ITGAL,ITGB2
2.197e-03	-6.12	granulocyte migration	biological process	GO:0097530	96	3	18204	49	MCOLN2,ITGB2,PREX1
2.201e-03	-6.12	angiogenesis	biological process	GO:0001525	342	5	18204	49	GAB1,RBPJ,ARHGAP24,PLXND1,ITGAV
2.205e-03	-6.12	KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1)	protein interactions	10657	358	5	19454	50	HCK,DOCK2,PTPN6,ARHGAP24,DISC1
2.207e-03	-6.12	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	4	19454	50	GAB1,DNM2,ARAP1,PTPN12
2.207e-03	-6.12	biological process involved in interspecies interaction between organisms	biological process	GO:0044419	1540	11	18204	49	FKBP5,HCK,MCOLN2,CD74,TFEB,CD68,PTGIR,ITGAV,PTPN6,RBPJ,STAB1
2.212e-03	-6.11	regulation of cell projection organization	biological process	GO:0031344	683	7	18204	49	DAB2,ARHGAP24,SEPTIN9,PREX1,DISC1,PLXND1,ARAP1
2.214e-03	-6.11	ruffle membrane	cellular component	GO:0032587	101	3	19108	49	ARHGAP45,ITGAV,TLN1
2.217e-03	-6.11	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	9	19454	50	TFEB,ARHGEF18,GAB1,DISC1,ZFP36L1,AKAP13,CD74,ITGB2,SH2B3
2.217e-03	-6.11	vWFA_dom_sf	interpro domains	IPR036465	96	3	18521	50	ITGAL,ANTXR2,ITGB2
2.226e-03	-6.11	membrane	cellular component	GO:0016020	9220	34	19108	49	ANTXR2,EHD4,DOCK8,WDFY3,PREX1,FYB1,MCOLN2,SH2B3,TLN1,ITGAV,PTGIR,CCND2,ITGAL,ARHGEF18,DOCK2,SLC9A7,FKBP5,AKAP13,STAB1,RGL1,CD68,MYO1F,TFEB,DNM2,ITM2B,DAB2,ARAP1,HEPHL1,ARHGAP45,HCK,ITGB2,PLXND1,CD74,PTPN6
2.284e-03	-6.08	cytoskeleton	cellular component	GO:0005856	2412	14	19108	49	HCK,PTPN12,TLN1,CCND2,ARHGEF18,DOCK2,DISC1,SEPTIN9,TMSB4X,AKAP13,FYB1,MYO1F,ARHGAP24,DNM2
2.286e-03	-6.08	chemotaxis	biological process	GO:0006935	345	5	18204	49	DOCK2,GAB1,ITGAV,ITGB2,PREX1
2.288e-03	-6.08	FG_GAP	prosite domains	PS51470	19	2	12186	46	ITGAV,ITGAL
2.300e-03	-6.07	regulation of cell population proliferation	biological process	GO:0042127	1790	12	18204	49	CD74,HCK,DISC1,BTG1,PTPN6,SH2B3,RBPJ,ZFP36L1,DAB2,CCND2,ITGAV,PTGIR
2.309e-03	-6.07	DH_2	prosite domains	PS50010	70	3	12186	46	AKAP13,PREX1,ARHGEF18
2.324e-03	-6.06	Cell death signalling via NRAGE, NRIF and NADE	REACTOME pathways	R-HSA-204998	76	3	10285	36	AKAP13,ARHGEF18,PREX1
2.344e-03	-6.06	positive regulation of signaling	biological process	GO:0023056	1794	12	18204	49	ITGAV,DAB2,BMP2K,RBM47,SPI1,ARAP1,DISC1,RXRA,RBPJ,PTPN6,AKAP13,CD74
2.344e-03	-6.06	breast-carcinoma-HER-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-HER-positive_carcinoma	2025	13	16828	46	DOCK8,WDFY3,PTPN6,RBPJ,BTG1,ELF4,ITGAL,RGL1,GAB1,TFEB,PTGIR,CCND2,TLN1
2.344e-03	-6.06	HER-positive_carcinoma	COSMIC cancer mutations	HER-positive_carcinoma	2025	13	16828	46	RBPJ,BTG1,ELF4,DOCK8,WDFY3,PTPN6,GAB1,TFEB,PTGIR,TLN1,CCND2,ITGAL,RGL1
2.344e-03	-6.06	taxis	biological process	GO:0042330	347	5	18204	49	ITGAV,PREX1,ITGB2,DOCK2,GAB1
2.345e-03	-6.06	PGAP1 (post-GPI attachment to proteins inositol deacylase 1)	protein interactions	80055	28	2	19454	50	DISC1,ITM2B
2.348e-03	-6.05	pleura	COSMIC cancer mutations	pleura	4914	23	16828	46	ELF4,BMP2K,RGL1,SH2B3,SPI1,CCND2,PTPN12,GAB1,PTPN6,ARHGAP24,BTG1,DAB2,RBPJ,FKBP5,ARHGEF18,AKAP13,ITGB2,PREX1,SLC9A7,TLN1,TFEB,HCK,ITGAV
2.382e-03	-6.04	AGR2 (anterior gradient 2, protein disulphide isomerase family member)	protein interactions	10551	930	8	19454	50	DOCK2,AKAP13,ME1,TLN1,DNM2,HCK,CD68,SEPTIN9
2.386e-03	-6.04	Integrin alpha, N-terminal	gene3d domains	2.130.10.130	22	2	14470	48	ITGAL,ITGAV
2.415e-03	-6.03	SH2DOMAIN	prints domains	PR00401	72	3	5227	20	HCK,SH2B3,PTPN6
2.430e-03	-6.02	RhoGAP	smart domains	SM00324	64	3	9717	41	ARHGAP45,ARAP1,ARHGAP24
2.447e-03	-6.01	EGF receptor (ErbB1) signaling pathway	Pathway Interaction DB	erbb1_receptor_proximal_pathway	25	3	2226	25	TLN1,GAB1,PTPN6
2.479e-03	-6.00	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	46	16828	46	ITGAL,SPI1,ME1,HEPHL1,TMSB4X,TFEB,STAB1,PREX1,ITM2B,DNM2,AKAP13,FKBP5,ARHGEF18,CD74,DAB2,ARHGAP24,ARAP1,MYO1F,DOCK2,DISC1,GAB1,MCOLN2,PTPN12,CCND2,RGL1,SH2B3,CD68,BMP2K,ELF4,DOCK8,WDFY3,PLXND1,ITGAV,HCK,TLN1,SLC9A7,PTGIR,ITGB2,RXRA,EHD4,RBPJ,BTG1,ZFP36L1,PTPN6,RBM47,ANTXR2
2.479e-03	-6.00	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	46	16828	46	MCOLN2,PTPN12,GAB1,CCND2,RGL1,SH2B3,BMP2K,CD68,ELF4,WDFY3,DOCK8,PLXND1,HCK,ITGAV,PTGIR,TLN1,SLC9A7,ITGB2,RXRA,RBPJ,EHD4,BTG1,ZFP36L1,ANTXR2,RBM47,PTPN6,SPI1,ITGAL,ME1,HEPHL1,TMSB4X,TFEB,STAB1,PREX1,ITM2B,DNM2,CD74,FKBP5,ARHGEF18,AKAP13,ARHGAP24,DAB2,MYO1F,DOCK2,ARAP1,DISC1
2.479e-03	-6.00	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	46	16828	46	ZFP36L1,ANTXR2,RBM47,PTPN6,RBPJ,EHD4,BTG1,ITGB2,RXRA,HCK,ITGAV,PTGIR,TLN1,SLC9A7,DOCK8,WDFY3,PLXND1,BMP2K,CD68,ELF4,SH2B3,RGL1,PTPN12,MCOLN2,GAB1,CCND2,DOCK2,MYO1F,ARAP1,DISC1,CD74,FKBP5,ARHGEF18,AKAP13,ARHGAP24,DAB2,ITM2B,DNM2,STAB1,TFEB,PREX1,TMSB4X,HEPHL1,SPI1,ITGAL,ME1
2.479e-03	-6.00	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	46	16828	46	PLXND1,DOCK8,WDFY3,ELF4,BMP2K,CD68,SH2B3,RGL1,CCND2,PTPN12,MCOLN2,GAB1,ANTXR2,RBM47,PTPN6,ZFP36L1,BTG1,RBPJ,EHD4,RXRA,ITGB2,PTGIR,SLC9A7,TLN1,HCK,ITGAV,TMSB4X,HEPHL1,ME1,SPI1,ITGAL,DISC1,DOCK2,MYO1F,ARAP1,ARHGAP24,DAB2,CD74,FKBP5,ARHGEF18,AKAP13,DNM2,ITM2B,PREX1,TFEB,STAB1
2.487e-03	-6.00	classic	COSMIC cancer mutations	classic	14774	46	16828	46	PLXND1,DOCK8,WDFY3,ELF4,CD68,BMP2K,SH2B3,RGL1,CCND2,GAB1,PTPN12,MCOLN2,PTPN6,RBM47,ANTXR2,ZFP36L1,BTG1,EHD4,RBPJ,RXRA,ITGB2,TLN1,SLC9A7,PTGIR,ITGAV,HCK,TMSB4X,HEPHL1,ME1,ITGAL,SPI1,DISC1,ARAP1,MYO1F,DOCK2,DAB2,ARHGAP24,AKAP13,ARHGEF18,FKBP5,CD74,DNM2,ITM2B,PREX1,STAB1,TFEB
2.494e-03	-5.99	regulation of cellular component size	biological process	GO:0032535	352	5	18204	49	DISC1,TMSB4X,HCK,DNM2,PREX1
2.518e-03	-5.98	medulla	COSMIC cancer mutations	medulla	14778	46	16828	46	ELF4,BMP2K,CD68,PLXND1,WDFY3,DOCK8,CCND2,PTPN12,MCOLN2,GAB1,RGL1,SH2B3,BTG1,RBPJ,EHD4,ANTXR2,RBM47,PTPN6,ZFP36L1,PTGIR,SLC9A7,TLN1,HCK,ITGAV,RXRA,ITGB2,HEPHL1,TMSB4X,ME1,SPI1,ITGAL,ARHGAP24,DAB2,CD74,ARHGEF18,FKBP5,AKAP13,DISC1,DOCK2,MYO1F,ARAP1,PREX1,TFEB,STAB1,DNM2,ITM2B
2.526e-03	-5.98	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	46	16828	46	ANTXR2,RBM47,PTPN6,ZFP36L1,BTG1,RBPJ,EHD4,RXRA,ITGB2,PTGIR,SLC9A7,TLN1,HCK,ITGAV,PLXND1,DOCK8,WDFY3,ELF4,BMP2K,CD68,SH2B3,RGL1,CCND2,MCOLN2,PTPN12,GAB1,DISC1,MYO1F,DOCK2,ARAP1,ARHGAP24,DAB2,CD74,FKBP5,ARHGEF18,AKAP13,DNM2,ITM2B,PREX1,TFEB,STAB1,TMSB4X,HEPHL1,ME1,SPI1,ITGAL
2.546e-03	-5.97	SH3-like_dom_sf	interpro domains	IPR036028	212	4	18521	50	FYB1,DOCK2,HCK,MYO1F
2.558e-03	-5.97	regulation of programmed cell death	biological process	GO:0043067	1569	11	18204	49	PTPN6,BTG1,CCND2,CD74,DNM2,DOCK8,ZFP36L1,DAB2,ITGAV,HCK,PLXND1
2.564e-03	-5.97	NOS2-CD74 complex	cellular component	GO:0035693	1	1	19108	49	CD74
2.570e-03	-5.96	Prkch (protein kinase C, eta)	protein interactions	81749	1	1	19454	50	AKAP13
2.570e-03	-5.96	Tfap2a (transcription factor AP-2 alpha)	protein interactions	306862	1	1	19454	50	DAB2
2.570e-03	-5.96	Parp1 (poly (ADP-ribose) polymerase 1)	protein interactions	25591	1	1	19454	50	RXRA
2.570e-03	-5.96	pparg.L (peroxisome proliferator activated receptor gamma L homeolog)	protein interactions	397769	1	1	19454	50	RXRA
2.570e-03	-5.96	ZNF880 (zinc finger protein 880)	protein interactions	400713	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	Kdm5 (Lysine demethylase 5)	protein interactions	33837	1	1	19454	50	RBPJ
2.570e-03	-5.96	ZNF729 (zinc finger protein 729)	protein interactions	100287226	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	H (Hairless)	protein interactions	42445	1	1	19454	50	RBPJ
2.570e-03	-5.96	ZNF780B (zinc finger protein 780B)	protein interactions	163131	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	EUC1 (Euc1p)	protein interactions	855138	1	1	19454	50	DOCK8
2.570e-03	-5.96	ZNF75D (zinc finger protein 75D)	protein interactions	7626	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	ZNF781 (zinc finger protein 781)	protein interactions	163115	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	NTA1 (amidase)	protein interactions	853525	1	1	19454	50	DOCK8
2.581e-03	-5.96	ETS_fam	interpro domains	IPR046328	28	2	18521	50	SPI1,ELF4
2.581e-03	-5.96	Ets_dom	interpro domains	IPR000418	28	2	18521	50	ELF4,SPI1
2.608e-03	-5.95	recycling endosome membrane	cellular component	GO:0055038	107	3	19108	49	MCOLN2,EHD4,SLC9A7
2.610e-03	-5.95	regulation of phagocytosis	biological process	GO:0050764	102	3	18204	49	DOCK2,HCK,ITGAV
2.628e-03	-5.94	CHMP2A (charged multivesicular body protein 2A)	protein interactions	27243	107	3	19454	50	FKBP5,RBPJ,DOCK8
2.629e-03	-5.94	regulation of cytoskeleton organization	biological process	GO:0051493	521	6	18204	49	ARHGEF18,HCK,PREX1,TMSB4X,ARAP1,AKAP13
2.630e-03	-5.94	SH2	pfam domains	PF00017	100	3	17795	49	SH2B3,HCK,PTPN6
2.675e-03	-5.92	BCAR1 (BCAR1 scaffold protein, Cas family member)	protein interactions	9564	547	6	19454	50	TLN1,DOCK2,PTPN12,HCK,FYB1,ITGAV
2.682e-03	-5.92	Ets	pfam domains	PF00178	28	2	17795	49	SPI1,ELF4
2.688e-03	-5.92	TGM2 (transglutaminase 2)	protein interactions	7052	226	4	19454	50	TMSB4X,DISC1,ITGAV,PREX1
2.690e-03	-5.92	PECAM1 (platelet and endothelial cell adhesion molecule 1)	protein interactions	5175	30	2	19454	50	HCK,PTPN6
2.690e-03	-5.92	regulation of lymphocyte differentiation	biological process	GO:0045619	216	4	18204	49	PTPN6,SPI1,CD74,ZFP36L1
2.692e-03	-5.92	leading edge cell differentiation	biological process	GO:0035026	1	1	18204	49	DAB2
2.692e-03	-5.92	macrophage migration inhibitory factor signaling pathway	biological process	GO:0035691	1	1	18204	49	CD74
2.692e-03	-5.92	entry into host cell by a symbiont-containing vacuole	biological process	GO:0085017	1	1	18204	49	ITGAV
2.692e-03	-5.92	memory T cell proliferation	biological process	GO:0061485	1	1	18204	49	DOCK8
2.692e-03	-5.92	positive regulation of ephrin receptor signaling pathway	biological process	GO:1901189	1	1	18204	49	RBPJ
2.700e-03	-5.91	ARHGEF18_PH	interpro domains	IPR037744	1	1	18521	50	ARHGEF18
2.700e-03	-5.91	BMP2K_C	interpro domains	IPR028182	1	1	18521	50	BMP2K
2.700e-03	-5.91	RBM47_RRM2	interpro domains	IPR034440	1	1	18521	50	RBM47
2.700e-03	-5.91	SH2B3_SH2	interpro domains	IPR035059	1	1	18521	50	SH2B3
2.700e-03	-5.91	MHCII_invariant_trimer_sf	interpro domains	IPR036613	1	1	18521	50	CD74
2.700e-03	-5.91	RBM47_RRM1	interpro domains	IPR047044	1	1	18521	50	RBM47
2.700e-03	-5.91	Integrin_b-2_sf	interpro domains	IPR015439	1	1	18521	50	ITGB2
2.700e-03	-5.91	RGL1_RA	interpro domains	IPR030748	1	1	18521	50	RGL1
2.700e-03	-5.91	DISC1	interpro domains	IPR026081	1	1	18521	50	DISC1
2.700e-03	-5.91	HCK_SH2	interpro domains	IPR035851	1	1	18521	50	HCK
2.700e-03	-5.91	MHC_II-assoc_invar/CLIP_MHC-bd	interpro domains	IPR015386	1	1	18521	50	CD74
2.700e-03	-5.91	Anthrax_toxin_rcpt	interpro domains	IPR017360	1	1	18521	50	ANTXR2
2.700e-03	-5.91	DHR2_DOCK2	interpro domains	IPR026799	1	1	18521	50	DOCK2
2.700e-03	-5.91	MHC_II-assoc_invariant_trimer	interpro domains	IPR011988	1	1	18521	50	CD74
2.700e-03	-5.91	bHLHzip_TFEB	interpro domains	IPR024098	1	1	18521	50	TFEB
2.700e-03	-5.91	LRMDA	interpro domains	IPR043313	1	1	18521	50	LRMDA
2.700e-03	-5.91	MHC_II-assoc_invar_chain	interpro domains	IPR022339	1	1	18521	50	CD74
2.700e-03	-5.91	Plexin-D1_Sema	interpro domains	IPR042719	1	1	18521	50	PLXND1
2.700e-03	-5.91	Prostglndn_IP_rcpt	interpro domains	IPR000370	1	1	18521	50	PTGIR
2.700e-03	-5.91	RBM47_RRM3	interpro domains	IPR034445	1	1	18521	50	RBM47
2.700e-03	-5.91	CD74_antigen	interpro domains	IPR043530	1	1	18521	50	CD74
2.700e-03	-5.91	PTN12_cat	interpro domains	IPR047251	1	1	18521	50	PTPN12
2.700e-03	-5.91	PTN12	interpro domains	IPR012266	1	1	18521	50	PTPN12
2.700e-03	-5.91	FYB_hSH3	interpro domains	IPR035540	1	1	18521	50	FYB1
2.708e-03	-5.91	prostacyclin receptor activity	molecular function	GO:0016501	1	1	18094	49	PTGIR
2.708e-03	-5.91	MHC class II protein binding, via antigen binding groove	molecular function	GO:0042658	1	1	18094	49	CD74
2.728e-03	-5.90	negative regulation of cellular component organization	biological process	GO:0051129	709	7	18204	49	ARAP1,TMSB4X,DNM2,ITGAV,DAB2,ARHGEF18,ARHGAP24
2.754e-03	-5.89	MHC2-interact	pfam domains	PF09307	1	1	17795	49	CD74
2.754e-03	-5.89	MHCassoc_trimer	pfam domains	PF08831	1	1	17795	49	CD74
2.754e-03	-5.89	BMP2K_C	pfam domains	PF15282	1	1	17795	49	BMP2K
2.758e-03	-5.89	regulation of actomyosin structure organization	biological process	GO:0110020	104	3	18204	49	AKAP13,ARAP1,ARHGEF18
2.763e-03	-5.89	immune response	biological process	GO:0006955	1349	10	18204	49	CD68,TFEB,ITGAL,RBPJ,PTPN6,DOCK2,HCK,MCOLN2,CD74,FYB1
2.784e-03	-5.88	protein sequestering activity	molecular function	GO:0140311	29	2	18094	49	TMSB4X,SPI1
2.838e-03	-5.86	Int_alpha	smart domains	SM00191	19	2	9717	41	ITGAL,ITGAV
2.842e-03	-5.86	KIT (KIT proto-oncogene, receptor tyrosine kinase)	protein interactions	3815	110	3	19454	50	SH2B3,HCK,PTPN6
2.862e-03	-5.86	blood vessel development	biological process	GO:0001568	530	6	18204	49	PLXND1,RBPJ,GAB1,ITGAV,ARHGAP24,ZFP36L1
2.870e-03	-5.85	CSF2RB (colony stimulating factor 2 receptor subunit beta)	protein interactions	1439	31	2	19454	50	PTPN6,HCK
2.874e-03	-5.85	regulation of peptidyl-tyrosine phosphorylation	biological process	GO:0050730	220	4	18204	49	ITGB2,EHD4,CD74,PTPN6
2.881e-03	-5.85	positive regulation of signal transduction	biological process	GO:0009967	1593	11	18204	49	RXRA,PTPN6,RBPJ,AKAP13,CD74,DAB2,BMP2K,ITGAV,RBM47,SPI1,DISC1
2.889e-03	-5.85	RhoGEF	smart domains	SM00325	68	3	9717	41	PREX1,ARHGEF18,AKAP13
2.921e-03	-5.84	regulation of cell-substrate adhesion	biological process	GO:0010810	221	4	18204	49	DISC1,PREX1,DAB2,TLN1
2.942e-03	-5.83	megakaryocyte differentiation	biological process	GO:0030219	30	2	18204	49	PTPN6,SH2B3
2.969e-03	-5.82	MAPK cascade	biological process	GO:0000165	222	4	18204	49	ITGAV,AKAP13,ZFP36L1,PTPN6
2.979e-03	-5.82	response to other organism	biological process	GO:0051707	1363	10	18204	49	TFEB,CD68,PTGIR,PTPN6,RBPJ,STAB1,FKBP5,HCK,MCOLN2,CD74
2.985e-03	-5.81	locomotion	biological process	GO:0040011	367	5	18204	49	ITGAV,PREX1,ITGB2,DOCK2,GAB1
2.991e-03	-5.81	ENAH (ENAH actin regulator)	protein interactions	55740	112	3	19454	50	ARHGEF18,ARHGAP24,FYB1
3.005e-03	-5.81	SH3_domain	interpro domains	IPR001452	222	4	18521	50	MYO1F,HCK,DOCK2,FYB1
3.027e-03	-5.80	response to external biotic stimulus	biological process	GO:0043207	1366	10	18204	49	TFEB,CD68,PTGIR,PTPN6,RBPJ,STAB1,FKBP5,HCK,MCOLN2,CD74
3.069e-03	-5.79	ETS_DOMAIN_1	prosite domains	PS00345	22	2	12186	46	SPI1,ELF4
3.102e-03	-5.78	large_cell	COSMIC cancer mutations	large_cell	14845	46	16828	46	MYO1F,DOCK2,ARAP1,DISC1,AKAP13,CD74,FKBP5,ARHGEF18,DAB2,ARHGAP24,ITM2B,DNM2,TFEB,STAB1,PREX1,TMSB4X,HEPHL1,ITGAL,SPI1,ME1,ZFP36L1,PTPN6,ANTXR2,RBM47,EHD4,RBPJ,BTG1,ITGB2,RXRA,HCK,ITGAV,SLC9A7,TLN1,PTGIR,WDFY3,DOCK8,PLXND1,CD68,BMP2K,ELF4,SH2B3,RGL1,MCOLN2,PTPN12,GAB1,CCND2
3.114e-03	-5.77	lytic vacuole	cellular component	GO:0000323	762	7	19108	49	TFEB,CD68,MCOLN2,CD74,DAB2,ARHGAP45,HCK
3.114e-03	-5.77	lysosome	cellular component	GO:0005764	762	7	19108	49	DAB2,CD74,MCOLN2,CD68,TFEB,HCK,ARHGAP45
3.127e-03	-5.77	macromolecule localization	biological process	GO:0033036	2376	14	18204	49	EHD4,FYB1,DISC1,TMSB4X,ITGB2,SEPTIN9,ARHGEF18,DAB2,ITGAL,ZFP36L1,MCOLN2,CD74,DNM2,CD68
3.140e-03	-5.76	antigen processing and presentation of exogenous peptide antigen via MHC class II	biological process	GO:0019886	31	2	18204	49	DNM2,CD74
3.161e-03	-5.76	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	21	16828	46	AKAP13,EHD4,FKBP5,ARHGEF18,WDFY3,DOCK2,DOCK8,MYO1F,PLXND1,RBM47,ITGAV,STAB1,PTPN12,TLN1,PREX1,ITGAL,ITGB2,ME1,RGL1,RXRA,SH2B3
3.161e-03	-5.76	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	21	16828	46	DOCK8,DOCK2,MYO1F,WDFY3,PLXND1,RBM47,EHD4,AKAP13,FKBP5,ARHGEF18,ITGAL,ITGB2,RXRA,RGL1,SH2B3,ME1,PTPN12,STAB1,ITGAV,TLN1,PREX1
3.179e-03	-5.75	SH2	interpro domains	IPR000980	109	3	18521	50	SH2B3,PTPN6,HCK
3.195e-03	-5.75	Farnesoid X Receptor Pathway	WikiPathways	WP2879	19	2	5310	24	FKBP5,RXRA
3.202e-03	-5.74	endosome membrane	cellular component	GO:0010008	569	6	19108	49	ANTXR2,EHD4,ITM2B,SLC9A7,CD68,MCOLN2
3.219e-03	-5.74	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-non_functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-non_functioning	224	4	16828	46	MCOLN2,EHD4,PTGIR,PLXND1
3.233e-03	-5.73	podosome	cellular component	GO:0002102	33	2	19108	49	PTPN12,DNM2
3.249e-03	-5.73	KATNAL1 (katanin catalytic subunit A1 like 1)	protein interactions	84056	33	2	19454	50	ARHGAP24,DISC1
3.270e-03	-5.72	developmental process	biological process	GO:0032502	5716	25	18204	49	PTPN6,GAB1,RXRA,DNM2,LRMDA,RBM47,ITM2B,SPI1,TFEB,DAB2,ZFP36L1,DISC1,PLXND1,ITGB2,HCK,RBPJ,DOCK2,CD74,AKAP13,PTPN12,SH2B3,ITGAV,ARHGAP24,ELF4,PREX1
3.282e-03	-5.72	cellular localization	biological process	GO:0051641	2660	15	18204	49	DOCK2,CD68,MCOLN2,CD74,DNM2,SEPTIN9,ITGAL,ARHGEF18,DAB2,FYB1,EHD4,TMSB4X,HCK,ITGB2,DISC1
3.300e-03	-5.71	Signaling by Rho GTPases	REACTOME pathways	R-HSA-194315	426	6	10285	36	ARAP1,ARHGAP45,ARHGEF18,PREX1,ARHGAP24,AKAP13
3.315e-03	-5.71	cell-cell adhesion	biological process	GO:0098609	546	6	18204	49	ITGAL,ZFP36L1,ITGAV,PTPN6,ITGB2,TLN1
3.317e-03	-5.71	-	gene3d domains	6.20.50.10	1	1	14470	48	ITGB2
3.317e-03	-5.71	-	gene3d domains	1.20.5.2120	1	1	14470	48	ITGAL
3.317e-03	-5.71	MHC class II-associated invariant chain, trimerisation domain	gene3d domains	1.10.870.10	1	1	14470	48	CD74
3.331e-03	-5.70	PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1)	protein interactions	5295	394	5	19454	50	HCK,DNM2,PTPN6,GAB1,RXRA
3.344e-03	-5.70	epiboly involved in wound healing	biological process	GO:0090505	32	2	18204	49	ARHGAP24,ITGAV
3.344e-03	-5.70	negative regulation of stress fiber assembly	biological process	GO:0051497	32	2	18204	49	ARHGEF18,ARAP1
3.344e-03	-5.70	wound healing, spreading of cells	biological process	GO:0044319	32	2	18204	49	ITGAV,ARHGAP24
3.344e-03	-5.70	peptidyl-tyrosine dephosphorylation	biological process	GO:0035335	32	2	18204	49	PTPN12,PTPN6
3.345e-03	-5.70	positive regulation of developmental process	biological process	GO:0051094	1385	10	18204	49	RBPJ,BTG1,GAB1,SPI1,RXRA,DAB2,ZFP36L1,CD74,PLXND1,DISC1
3.400e-03	-5.68	mononuclear cell migration	biological process	GO:0071674	112	3	18204	49	DOCK8,ITGAL,MCOLN2
3.402e-03	-5.68	Innate Immune System	REACTOME pathways	R-HSA-168249	1285	11	10285	36	TLN1,GAB1,ARHGAP45,PTPN6,DNM2,ITGAV,ITGB2,ITGAL,HCK,CD68,DOCK2
3.403e-03	-5.68	cell adhesion	biological process	GO:0007155	942	8	18204	49	ITGB2,TLN1,HCK,PTPN6,STAB1,ITGAL,ZFP36L1,ITGAV
3.436e-03	-5.67	vasculature development	biological process	GO:0001944	550	6	18204	49	GAB1,RBPJ,ARHGAP24,ZFP36L1,ITGAV,PLXND1
3.446e-03	-5.67	ELMO1 (engulfment and cell motility 1)	protein interactions	9844	34	2	19454	50	DOCK2,HCK
3.446e-03	-5.67	PRKCH (protein kinase C eta)	protein interactions	5583	34	2	19454	50	AKAP13,ITGB2
3.487e-03	-5.66	negative regulation of signal transduction	biological process	GO:0009968	1393	10	18204	49	CD74,TMSB4X,PTPN12,SH2B3,PTPN6,SPI1,PTGIR,ITGAV,ARHGAP24,DAB2
3.519e-03	-5.65	SH2_dom_sf	interpro domains	IPR036860	113	3	18521	50	SH2B3,HCK,PTPN6
3.523e-03	-5.65	regulation of catalytic activity	biological process	GO:0050790	1395	10	18204	49	ARHGAP24,CCND2,ARHGAP45,CD74,PREX1,TMSB4X,ITGB2,DOCK8,PLXND1,ARAP1
3.524e-03	-5.65	G alpha (12/13) signalling events	REACTOME pathways	R-HSA-416482	88	3	10285	36	AKAP13,ARHGEF18,PREX1
3.546e-03	-5.64	signaling adaptor activity	molecular function	GO:0035591	113	3	18094	49	AKAP13,SH2B3,GAB1
3.553e-03	-5.64	epiboly	biological process	GO:0090504	33	2	18204	49	ITGAV,ARHGAP24
3.553e-03	-5.64	antigen processing and presentation of peptide antigen via MHC class II	biological process	GO:0002495	33	2	18204	49	CD74,DNM2
3.590e-03	-5.63	ITSN1 (intersectin 1)	protein interactions	6453	245	4	19454	50	DISC1,DNM2,DAB2,PREX1
3.649e-03	-5.61	Mbp (myelin basic protein)	protein interactions	17196	35	2	19454	50	FYB1,HCK
3.696e-03	-5.60	PICALM (phosphatidylinositol binding clathrin assembly protein)	protein interactions	8301	247	4	19454	50	RBM47,DAB2,DNM2,BMP2K
3.718e-03	-5.59	POLR3B (RNA polymerase III subunit B)	protein interactions	55703	121	3	19454	50	CD74,RBPJ,FKBP5
3.749e-03	-5.59	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	4	19454	50	ITGAV,RXRA,RBPJ,CCND2
3.769e-03	-5.58	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	biological process	GO:0002504	34	2	18204	49	DNM2,CD74
3.769e-03	-5.58	positive T cell selection	biological process	GO:0043368	34	2	18204	49	CD74,DOCK2
3.794e-03	-5.57	breast-carcinoma-ER-PR-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-ER-PR-positive_carcinoma	1881	12	16828	46	RGL1,ITGAL,TLN1,CCND2,PTGIR,TFEB,PTPN12,GAB1,PTPN6,ELF4,BTG1,RBPJ
3.794e-03	-5.57	ER-PR-positive_carcinoma	COSMIC cancer mutations	ER-PR-positive_carcinoma	1881	12	16828	46	BTG1,ELF4,RBPJ,PTPN6,PTGIR,CCND2,TLN1,TFEB,PTPN12,GAB1,RGL1,ITGAL
3.803e-03	-5.57	ICAM1 (intercellular adhesion molecule 1)	protein interactions	3383	249	4	19454	50	ITGAL,SEPTIN9,WDFY3,ITGB2
3.826e-03	-5.57	CD74ANTIGEN	prints domains	PR01990	1	1	5227	20	CD74
3.826e-03	-5.57	PRSTNOIDIPR	prints domains	PR00856	1	1	5227	20	PTGIR
3.827e-03	-5.57	immune effector process	biological process	GO:0002252	389	5	18204	49	DOCK2,PTPN6,CD74,HCK,ITGAL
3.836e-03	-5.56	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	8	19454	50	PREX1,EHD4,ARAP1,DOCK8,ITGAV,GAB1,DOCK2,DAB2
3.857e-03	-5.56	TBC1D14 (TBC1 domain family member 14)	protein interactions	57533	36	2	19454	50	HEPHL1,TFEB
3.857e-03	-5.56	DPP7 (dipeptidyl peptidase 7)	protein interactions	29952	36	2	19454	50	HCK,PTPN12
3.857e-03	-5.56	SGIP1 (SH3GL interacting endocytic adaptor 1)	protein interactions	84251	36	2	19454	50	DAB2,HEPHL1
3.905e-03	-5.55	LIMA1 (LIM domain and actin binding 1)	protein interactions	51474	409	5	19454	50	ARHGAP24,DISC1,SEPTIN9,BMP2K,DAB2
3.916e-03	-5.54	anatomical structure formation involved in morphogenesis	biological process	GO:0048646	964	8	18204	49	ITGB2,ARHGAP24,ITGAV,PLXND1,GAB1,DOCK2,PTPN6,RBPJ
3.931e-03	-5.54	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	7	16828	46	DNM2,BTG1,HCK,ITGAV,CD74,ZFP36L1,WDFY3
3.937e-03	-5.54	regulation of receptor-mediated endocytosis	biological process	GO:0048259	118	3	18204	49	ITGAV,DAB2,BMP2K
3.939e-03	-5.54	RA	pfam domains	PF00788	34	2	17795	49	ARAP1,RGL1
3.969e-03	-5.53	DCAF15 (DDB1 and CUL4 associated factor 15)	protein interactions	90379	252	4	19454	50	TLN1,PTPN12,DOCK2,SEPTIN9
3.980e-03	-5.53	FLNA (filamin A)	protein interactions	2316	593	6	19454	50	PTPN12,DAB2,SH2B3,DISC1,ARHGAP24,BMP2K
3.990e-03	-5.52	negative regulation of actin filament bundle assembly	biological process	GO:0032232	35	2	18204	49	ARHGEF18,ARAP1
4.025e-03	-5.52	PRRC2C (proline rich coiled-coil 2C)	protein interactions	23215	253	4	19454	50	CD74,FKBP5,TLN1,RBM47
4.057e-03	-5.51	non_functioning	COSMIC cancer mutations	non_functioning	239	4	16828	46	EHD4,MCOLN2,PLXND1,PTGIR
4.139e-03	-5.49	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	38	16828	46	ITGAL,SPI1,RGL1,SH2B3,ME1,PTPN12,MCOLN2,GAB1,DOCK8,WDFY3,CD68,BMP2K,ELF4,HEPHL1,ITGB2,DNM2,RXRA,TFEB,STAB1,HCK,ITGAV,SLC9A7,TLN1,PTGIR,PREX1,ZFP36L1,MYO1F,DOCK2,ARAP1,ANTXR2,RBM47,AKAP13,EHD4,RBPJ,ARHGEF18,FKBP5,DAB2,ARHGAP24
4.252e-03	-5.46	Gap junction trafficking	REACTOME pathways	R-HSA-190828	28	2	10285	36	DNM2,DAB2
4.277e-03	-5.45	ETS_DOMAIN_2	prosite domains	PS00346	26	2	12186	46	SPI1,ELF4
4.316e-03	-5.45	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	10	19454	50	ITM2B,SPI1,CD74,ITGAV,ITGAL,ITGB2,DNM2,HCK,RXRA,ELF4
4.352e-03	-5.44	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	3	19454	50	DISC1,ELF4,DNM2
4.382e-03	-5.43	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	7	16828	46	BMP2K,ITGAV,HCK,CCND2,ZFP36L1,RBM47,ME1
4.382e-03	-5.43	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	7	16828	46	CCND2,BMP2K,ITGAV,HCK,RBM47,ME1,ZFP36L1
4.396e-03	-5.43	SH3 domain binding	molecular function	GO:0017124	122	3	18094	49	PTPN12,DNM2,PTPN6
4.433e-03	-5.42	XRCC6 (X-ray repair cross complementing 6)	protein interactions	2547	810	7	19454	50	ARHGAP24,BTG1,DISC1,RBPJ,RXRA,ARAP1,DNM2
4.451e-03	-5.41	negative regulation of lymphocyte apoptotic process	biological process	GO:0070229	37	2	18204	49	DOCK8,CD74
4.451e-03	-5.41	cellular response to low-density lipoprotein particle stimulus	biological process	GO:0071404	37	2	18204	49	ITGB2,CD68
4.451e-03	-5.41	response to lipoprotein particle	biological process	GO:0055094	37	2	18204	49	CD68,ITGB2
4.483e-03	-5.41	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	29	16828	46	WDFY3,DOCK8,ELF4,HEPHL1,SH2B3,RGL1,ME1,ITGAL,CCND2,PTPN12,MCOLN2,GAB1,ANTXR2,MYO1F,DOCK2,ARAP1,DAB2,AKAP13,EHD4,FKBP5,ARHGEF18,DNM2,RXRA,ITGB2,SLC9A7,TLN1,PREX1,STAB1,ITGAV
4.523e-03	-5.40	positive regulation of cell-substrate adhesion	biological process	GO:0010811	124	3	18204	49	DAB2,PREX1,DISC1
4.523e-03	-5.40	regulation of ossification	biological process	GO:0030278	124	3	18204	49	RBPJ,RXRA,BMP2K
4.525e-03	-5.40	endomembrane system	cellular component	GO:0012505	4764	21	19108	49	CD68,MCOLN2,DNM2,ITM2B,DAB2,ANTXR2,EHD4,WDFY3,TMSB4X,CCND2,ITGAL,CD74,DOCK2,SLC9A7,DISC1,PTPN6,ARAP1,ARHGAP45,HCK,ITGB2,ITGAV
4.557e-03	-5.39	The role of Nef in HIV-1 replication and disease pathogenesis	REACTOME pathways	R-HSA-164952	29	2	10285	36	HCK,DOCK2
4.568e-03	-5.39	Bacterial invasion of epithelial cells	KEGG pathways	hsa05100	76	3	7161	32	GAB1,SEPTIN9,DNM2
4.568e-03	-5.39	Bacterial invasion of epithelial cells	KEGG pathways	ko05100	76	3	7161	32	SEPTIN9,GAB1,DNM2
4.634e-03	-5.37	p75 NTR receptor-mediated signalling	REACTOME pathways	R-HSA-193704	97	3	10285	36	AKAP13,ARHGEF18,PREX1
4.674e-03	-5.37	cell leading edge	cellular component	GO:0031252	428	5	19108	49	ARHGAP45,DOCK8,PLXND1,ITGAV,TLN1
4.691e-03	-5.36	heterotypic cell-cell adhesion	biological process	GO:0034113	38	2	18204	49	ITGAV,ITGB2
4.704e-03	-5.36	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	29	16828	46	MYO1F,DOCK2,ARAP1,ANTXR2,RBM47,AKAP13,CD74,RBPJ,ARHGEF18,DAB2,ARHGAP24,ITM2B,RXRA,STAB1,ITGAV,SLC9A7,TLN1,PREX1,DOCK8,WDFY3,PLXND1,BMP2K,ELF4,HEPHL1,ITGAL,MCOLN2,PTPN12,GAB1,CCND2
4.704e-03	-5.36	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	29	16828	46	DOCK8,WDFY3,PLXND1,BMP2K,HEPHL1,ELF4,ITGAL,GAB1,PTPN12,MCOLN2,CCND2,ARAP1,MYO1F,DOCK2,RBM47,ANTXR2,AKAP13,ARHGEF18,CD74,RBPJ,DAB2,ARHGAP24,ITM2B,RXRA,ITGAV,STAB1,SLC9A7,TLN1,PREX1
4.705e-03	-5.36	plasma membrane region	cellular component	GO:0098590	1278	9	19108	49	DNM2,PLXND1,ARHGEF18,ITGAV,TLN1,ITGB2,HCK,ARHGAP45,DOCK8
4.777e-03	-5.34	ACTG1 (actin gamma 1)	protein interactions	71	429	5	19454	50	DISC1,ARHGAP24,TMSB4X,FKBP5,PTPN12
4.852e-03	-5.33	cellular process	biological process	GO:0009987	14996	47	18204	49	MYO1F,RXRA,BTG1,DNM2,RGL1,FKBP5,ARHGEF18,ZFP36L1,ITGAL,DAB2,SPI1,SEPTIN9,SLC9A7,ARAP1,HCK,CCND2,RBPJ,DOCK8,CD74,MCOLN2,ITGAV,ARHGAP45,BMP2K,PTPN12,TMSB4X,ELF4,WDFY3,GAB1,PTPN6,LRMDA,TFEB,RBM47,DISC1,PLXND1,ITGB2,EHD4,CD68,PTGIR,DOCK2,AKAP13,ARHGAP24,STAB1,SH2B3,PREX1,TLN1,ME1,FYB1
4.853e-03	-5.33	anatomical structure development	biological process	GO:0048856	5207	23	18204	49	PTPN12,SH2B3,ITGAV,ARHGAP24,PREX1,RBPJ,DOCK2,CD74,AKAP13,SPI1,ITM2B,RBM47,DAB2,ZFP36L1,TFEB,PLXND1,DISC1,HCK,ITGB2,GAB1,PTPN6,RXRA,DNM2
4.872e-03	-5.32	Gap junction trafficking and regulation	REACTOME pathways	R-HSA-157858	30	2	10285	36	DNM2,DAB2
4.897e-03	-5.32	amide binding	molecular function	GO:0033218	254	4	18094	49	ITGB2,FKBP5,ITM2B,CD74
4.950e-03	-5.31	ETS_DOMAIN_3	prosite domains	PS50061	28	2	12186	46	SPI1,ELF4
4.954e-03	-5.31	ETSDOMAIN	prints domains	PR00454	28	2	5227	20	SPI1,ELF4
4.966e-03	-5.31	RA_dom	interpro domains	IPR000159	39	2	18521	50	ARAP1,RGL1
4.980e-03	-5.30	NR3C2 (nuclear receptor subfamily 3 group C member 2)	protein interactions	4306	41	2	19454	50	FKBP5,RXRA
4.980e-03	-5.30	SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3)	protein interactions	9901	41	2	19454	50	ARHGAP24,DISC1
5.061e-03	-5.29	FN1 (fibronectin 1)	protein interactions	2335	830	7	19454	50	DAB2,BMP2K,ITGAV,DISC1,TLN1,DNM2,SEPTIN9
5.065e-03	-5.29	small GTPase-mediated signal transduction	biological process	GO:0007264	258	4	18204	49	DOCK2,ARHGEF18,RGL1,DOCK8
5.104e-03	-5.28	cellular response to organic substance	biological process	GO:0071310	1716	11	18204	49	TMSB4X,HCK,DOCK8,CD74,ZFP36L1,RXRA,CD68,PTPN6,SPI1,GAB1,SH2B3
5.122e-03	-5.27	integrin alphav-beta1 complex	cellular component	GO:0034682	2	1	19108	49	ITGAV
5.122e-03	-5.27	integrin alphav-beta5 complex	cellular component	GO:0034684	2	1	19108	49	ITGAV
5.122e-03	-5.27	integrin alphav-beta8 complex	cellular component	GO:0034686	2	1	19108	49	ITGAV
5.122e-03	-5.27	integrin alphaM-beta2 complex	cellular component	GO:0034688	2	1	19108	49	ITGB2
5.122e-03	-5.27	macrophage migration inhibitory factor receptor complex	cellular component	GO:0035692	2	1	19108	49	CD74
5.122e-03	-5.27	integrin alphav-beta6 complex	cellular component	GO:0034685	2	1	19108	49	ITGAV
5.122e-03	-5.27	integrin alphaX-beta2 complex	cellular component	GO:0034689	2	1	19108	49	ITGB2
5.125e-03	-5.27	HTLV-I infection	KEGG pathways	hsa05166	256	5	7161	32	ITGAL,ITGB2,TLN1,CCND2,SPI1
5.125e-03	-5.27	HTLV-I infection	KEGG pathways	ko05166	256	5	7161	32	TLN1,CCND2,ITGAL,ITGB2,SPI1
5.134e-03	-5.27	ZNF658B (zinc finger protein 658B (pseudogene))	protein interactions	401509	2	1	19454	50	ARHGAP24
5.134e-03	-5.27	LIPI (lipase I)	protein interactions	149998	2	1	19454	50	SEPTIN9
5.134e-03	-5.27	KIR2DL5A (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A)	protein interactions	57292	2	1	19454	50	PTPN6
5.134e-03	-5.27	Cnot7 (CCR4-NOT transcription complex, subunit 7)	protein interactions	18983	2	1	19454	50	BTG1
5.134e-03	-5.27	MPIG6B (megakaryocyte and platelet inhibitory receptor G6b)	protein interactions	80739	2	1	19454	50	PTPN6
5.134e-03	-5.27	Siglece (sialic acid binding Ig-like lectin E)	protein interactions	83382	2	1	19454	50	PTPN6
5.134e-03	-5.27	ZNF680 (zinc finger protein 680)	protein interactions	340252	2	1	19454	50	ARHGAP24
5.134e-03	-5.27	CUZD1 (CUB and zona pellucida like domains 1)	protein interactions	50624	2	1	19454	50	PTPN6
5.153e-03	-5.27	ITGB5 (integrin subunit beta 5)	protein interactions	3693	136	3	19454	50	ITGAV,TLN1,DAB2
5.153e-03	-5.27	PYGB (glycogen phosphorylase B)	protein interactions	5834	136	3	19454	50	ARHGAP24,FYB1,FKBP5
5.174e-03	-5.26	peptide binding	molecular function	GO:0042277	258	4	18094	49	CD74,ITGB2,RXRA,ITM2B
5.187e-03	-5.26	cellular response to lipoprotein particle stimulus	biological process	GO:0071402	40	2	18204	49	CD68,ITGB2
5.198e-03	-5.26	RDX (radixin)	protein interactions	5962	272	4	19454	50	TLN1,ITGB2,SEPTIN9,ARHGAP24
5.199e-03	-5.26	APP (amyloid beta precursor protein)	protein interactions	351	2342	13	19454	50	SEPTIN9,DNM2,ARAP1,HCK,RGL1,ARHGAP24,AKAP13,CD74,FKBP5,DAB2,RBPJ,PTPN12,ITM2B
5.220e-03	-5.26	OAZ3 (ornithine decarboxylase antizyme 3)	protein interactions	51686	42	2	19454	50	HEPHL1,ME1
5.220e-03	-5.26	NSMAF (neutral sphingomyelinase activation associated factor)	protein interactions	8439	42	2	19454	50	HEPHL1,DOCK8
5.276e-03	-5.24	positive regulation of immune effector process	biological process	GO:0002699	261	4	18204	49	ITGB2,SPI1,PTPN6,CD74
5.278e-03	-5.24	human chr19p13.2	chromosome location	human chr19p13.2	184	3	26134	50	DNM2,ARHGEF18,MYO1F
5.358e-03	-5.23	enzyme activator activity	molecular function	GO:0008047	599	6	18094	49	ARHGAP24,CCND2,ARAP1,DOCK2,ARHGAP45,PREX1
5.370e-03	-5.23	regulation of cellular component biogenesis	biological process	GO:0044087	1016	8	18204	49	TLN1,PREX1,HCK,TMSB4X,ARAP1,ARHGEF18,ARHGAP24,SEPTIN9
5.376e-03	-5.23	blood vessel lumenization	biological process	GO:0072554	2	1	18204	49	RBPJ
5.376e-03	-5.23	negative regulation of entry of bacterium into host cell	biological process	GO:2000536	2	1	18204	49	ITGAV
5.376e-03	-5.23	positive regulation of macrophage migration inhibitory factor signaling pathway	biological process	GO:2000448	2	1	18204	49	CD74
5.376e-03	-5.23	regulation of ephrin receptor signaling pathway	biological process	GO:1901187	2	1	18204	49	RBPJ
5.376e-03	-5.23	negative regulation of dopamine metabolic process	biological process	GO:0045963	2	1	18204	49	ITGB2
5.376e-03	-5.23	positive regulation of macrophage inflammatory protein 1 alpha production	biological process	GO:0071642	2	1	18204	49	MCOLN2
5.376e-03	-5.23	regulation of prostaglandin-E synthase activity	biological process	GO:2000361	2	1	18204	49	ITGB2
5.376e-03	-5.23	memory T cell extravasation	biological process	GO:0035683	2	1	18204	49	ITGAL
5.376e-03	-5.23	negative regulation of membrane tubulation	biological process	GO:1903526	2	1	18204	49	DNM2
5.376e-03	-5.23	arterial endothelial cell fate commitment	biological process	GO:0060844	2	1	18204	49	RBPJ
5.376e-03	-5.23	regulation of Kit signaling pathway	biological process	GO:1900234	2	1	18204	49	SH2B3
5.376e-03	-5.23	regulation of cell adhesion involved in heart morphogenesis	biological process	GO:0061344	2	1	18204	49	RBPJ
5.376e-03	-5.23	negative regulation of Kit signaling pathway	biological process	GO:1900235	2	1	18204	49	SH2B3
5.376e-03	-5.23	negative regulation of neutrophil degranulation	biological process	GO:0043314	2	1	18204	49	SPI1
5.376e-03	-5.23	NK T cell activation	biological process	GO:0051132	2	1	18204	49	ELF4
5.376e-03	-5.23	pro-T cell differentiation	biological process	GO:0002572	2	1	18204	49	SPI1
5.376e-03	-5.23	positive regulation of prostaglandin-E synthase activity	biological process	GO:2000363	2	1	18204	49	ITGB2
5.376e-03	-5.23	positive regulation of thyroid hormone mediated signaling pathway	biological process	GO:0002157	2	1	18204	49	RXRA
5.376e-03	-5.23	negative regulation of catecholamine metabolic process	biological process	GO:0045914	2	1	18204	49	ITGB2
5.376e-03	-5.23	synaptic target recognition	biological process	GO:0008039	2	1	18204	49	PLXND1
5.376e-03	-5.23	NK T cell proliferation	biological process	GO:0001866	2	1	18204	49	ELF4
5.376e-03	-5.23	vesicle scission	biological process	GO:0099050	2	1	18204	49	DNM2
5.390e-03	-5.22	endosome	cellular component	GO:0005768	1067	8	19108	49	CD74,DNM2,SLC9A7,ITM2B,CD68,MCOLN2,ANTXR2,EHD4
5.392e-03	-5.22	Dab_PTB	interpro domains	IPR048561	2	1	18521	50	DAB2
5.392e-03	-5.22	RBP-J/Cbf11/Cbf12_DNA-bd	interpro domains	IPR015351	2	1	18521	50	RBPJ
5.392e-03	-5.22	Tyr_Pase_non-rcpt_typ-6/11	interpro domains	IPR012152	2	1	18521	50	PTPN6
5.392e-03	-5.22	Beta-trefoil_DNA-bd_dom	interpro domains	IPR015350	2	1	18521	50	RBPJ
5.392e-03	-5.22	Talin1/2-RS	interpro domains	IPR037438	2	1	18521	50	TLN1
5.392e-03	-5.22	Tis11B_N	interpro domains	IPR007635	2	1	18521	50	ZFP36L1
5.392e-03	-5.22	CLS_fam	interpro domains	IPR040159	2	1	18521	50	RBPJ
5.392e-03	-5.22	Nuc_recep-AF1	interpro domains	IPR021780	2	1	18521	50	RXRA
5.392e-03	-5.22	Ie/If_SH3	interpro domains	IPR035507	2	1	18521	50	MYO1F
5.392e-03	-5.22	RBP-J/Cbf11_DNA-bd_sf	interpro domains	IPR037095	2	1	18521	50	RBPJ
5.392e-03	-5.22	Anthrax_toxin_rcpt_C	interpro domains	IPR008399	2	1	18521	50	ANTXR2
5.392e-03	-5.22	Talin_cent_sf	interpro domains	IPR036476	2	1	18521	50	TLN1
5.392e-03	-5.22	BTD_sf	interpro domains	IPR036358	2	1	18521	50	RBPJ
5.392e-03	-5.22	Talin_cent	interpro domains	IPR015224	2	1	18521	50	TLN1
5.392e-03	-5.22	DAB1/2_SBM	interpro domains	IPR048559	2	1	18521	50	DAB2
5.392e-03	-5.22	Vinculin-bd_dom	interpro domains	IPR015009	2	1	18521	50	TLN1
5.392e-03	-5.22	RBP-Jkappa_IPT	interpro domains	IPR038007	2	1	18521	50	RBPJ
5.392e-03	-5.22	Talin_R4	interpro domains	IPR049108	2	1	18521	50	TLN1
5.409e-03	-5.22	macrophage migration inhibitory factor binding	molecular function	GO:0035718	2	1	18094	49	CD74
5.419e-03	-5.22	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	43	16828	46	SPI1,ITGAL,ME1,TMSB4X,HEPHL1,DNM2,TFEB,STAB1,PREX1,ARAP1,DOCK2,MYO1F,DISC1,FKBP5,ARHGEF18,CD74,AKAP13,ARHGAP24,DAB2,RGL1,SH2B3,GAB1,PTPN12,MCOLN2,CCND2,WDFY3,DOCK8,PLXND1,BMP2K,ELF4,ITGB2,RXRA,ITGAV,HCK,PTGIR,TLN1,SLC9A7,ZFP36L1,RBM47,PTPN6,RBPJ,EHD4,BTG1
5.443e-03	-5.21	inflammatory response to antigenic stimulus	biological process	GO:0002437	41	2	18204	49	CD68,RBPJ
5.443e-03	-5.21	antigen processing and presentation of exogenous peptide antigen	biological process	GO:0002478	41	2	18204	49	DNM2,CD74
5.469e-03	-5.21	EPO signaling pathway	Pathway Interaction DB	epopathway	33	3	2226	25	SH2B3,GAB1,PTPN6
5.471e-03	-5.21	FLII (FLII actin remodeling protein)	protein interactions	2314	276	4	19454	50	FKBP5,CCND2,RBPJ,DISC1
5.494e-03	-5.20	negative regulation of cell communication	biological process	GO:0010648	1485	10	18204	49	SH2B3,PTPN12,PTPN6,SPI1,PTGIR,ITGAV,ARHGAP24,DAB2,CD74,TMSB4X
5.494e-03	-5.20	negative regulation of signaling	biological process	GO:0023057	1485	10	18204	49	ARHGAP24,DAB2,PTGIR,ITGAV,PTPN6,SPI1,PTPN12,SH2B3,TMSB4X,CD74
5.500e-03	-5.20	TIG_SUH	pfam domains	PF20144	2	1	17795	49	RBPJ
5.500e-03	-5.20	DAB2_SBM	pfam domains	PF21792	2	1	17795	49	DAB2
5.500e-03	-5.20	Nuc_recep-AF1	pfam domains	PF11825	2	1	17795	49	RXRA
5.500e-03	-5.20	Talin_middle	pfam domains	PF09141	2	1	17795	49	TLN1
5.500e-03	-5.20	Tis11B_N	pfam domains	PF04553	2	1	17795	49	ZFP36L1
5.500e-03	-5.20	Talin_R4	pfam domains	PF21692	2	1	17795	49	TLN1
5.500e-03	-5.20	BTD	pfam domains	PF09270	2	1	17795	49	RBPJ
5.500e-03	-5.20	LAG1-DNAbind	pfam domains	PF09271	2	1	17795	49	RBPJ
5.500e-03	-5.20	VBS	pfam domains	PF08913	2	1	17795	49	TLN1
5.500e-03	-5.20	Ant_C	pfam domains	PF05586	2	1	17795	49	ANTXR2
5.554e-03	-5.19	lytic vacuole membrane	cellular component	GO:0098852	446	5	19108	49	CD74,DAB2,CD68,TFEB,MCOLN2
5.554e-03	-5.19	lysosomal membrane	cellular component	GO:0005765	446	5	19108	49	DAB2,CD74,MCOLN2,CD68,TFEB
5.611e-03	-5.18	cytoskeleton organization	biological process	GO:0007010	1251	9	18204	49	ARHGEF18,MYO1F,DOCK2,TMSB4X,PREX1,DNM2,TLN1,ARAP1,DISC1
5.612e-03	-5.18	regulation of actin filament polymerization	biological process	GO:0030833	134	3	18204	49	TMSB4X,PREX1,HCK
5.717e-03	-5.16	FNBP1L (formin binding protein 1 like)	protein interactions	54874	44	2	19454	50	DNM2,RBPJ
5.717e-03	-5.16	ICAM4 (intercellular adhesion molecule 4 (Landsteiner-Wiener blood group))	protein interactions	3386	44	2	19454	50	ITGAV,ITGB2
5.717e-03	-5.16	FER (FER tyrosine kinase)	protein interactions	2241	44	2	19454	50	FKBP5,DNM2
5.721e-03	-5.16	negative regulation of response to external stimulus	biological process	GO:0032102	428	5	18204	49	PTPN6,ELF4,SH2B3,TMSB4X,HCK
5.738e-03	-5.16	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	6	10285	36	AKAP13,PREX1,DNM2,TLN1,GAB1,ARHGEF18
5.740e-03	-5.16	PTP_cat	interpro domains	IPR000242	42	2	18521	50	PTPN6,PTPN12
5.740e-03	-5.16	PSI	interpro domains	IPR016201	42	2	18521	50	ITGB2,PLXND1
5.826e-03	-5.15	SKP2 (S-phase kinase associated protein 2)	protein interactions	6502	281	4	19454	50	CCND2,DISC1,BTG1,ELF4
5.847e-03	-5.14	cell-matrix adhesion	biological process	GO:0007160	136	3	18204	49	ITGAV,ITGAL,ITGB2
5.890e-03	-5.13	response to wounding	biological process	GO:0009611	431	5	18204	49	PTPN6,ITGAV,ZFP36L1,TLN1,ARHGAP24
5.913e-03	-5.13	SH2 domain	gene3d domains	3.30.505.10	111	3	14470	48	SH2B3,PTPN6,HCK
5.952e-03	-5.12	Adaptive Immune System	REACTOME pathways	R-HSA-1280218	810	8	10285	36	PTPN6,GAB1,FYB1,CD74,ITGAL,ITGB2,ITGAV,DNM2
5.962e-03	-5.12	Y_phosphatase	pfam domains	PF00102	42	2	17795	49	PTPN12,PTPN6
5.967e-03	-5.12	cell recognition	biological process	GO:0008037	137	3	18204	49	DOCK2,PLXND1,DOCK8
5.967e-03	-5.12	myeloid leukocyte migration	biological process	GO:0097529	137	3	18204	49	PREX1,ITGB2,MCOLN2
5.973e-03	-5.12	SPTBN4 (spectrin beta, non-erythrocytic 4)	protein interactions	57731	45	2	19454	50	ANTXR2,DISC1
5.973e-03	-5.12	SMARCAL1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1)	protein interactions	50485	45	2	19454	50	FKBP5,RBPJ
5.973e-03	-5.12	ITGAD (integrin subunit alpha D)	protein interactions	3681	45	2	19454	50	HEPHL1,ITGB2
5.973e-03	-5.12	EPOR (erythropoietin receptor)	protein interactions	2057	45	2	19454	50	GAB1,PTPN6
5.973e-03	-5.12	SKAP2 (src kinase associated phosphoprotein 2)	protein interactions	8935	45	2	19454	50	HCK,FYB1
5.974e-03	-5.12	positive regulation of substrate adhesion-dependent cell spreading	biological process	GO:1900026	43	2	18204	49	PREX1,DAB2
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	PTPN6,DNM2,HCK,GAB1,SH2B3
6.126e-03	-5.10	ETS	smart domains	SM00413	28	2	9717	41	SPI1,ELF4
6.234e-03	-5.08	ICAM5 (intercellular adhesion molecule 5)	protein interactions	7087	46	2	19454	50	ITGB2,ITGAL
6.287e-03	-5.07	SH3 Domains	gene3d domains	2.30.30.40	223	4	14470	48	MYO1F,DOCK2,FYB1,HCK
6.332e-03	-5.06	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	46	AKAP13,BMP2K,ARAP1,ZFP36L1,DOCK2,PTPN6,PLXND1,ANTXR2,ITGAV,PTPN12,HCK,SLC9A7,TLN1,ITGAL,ME1
6.332e-03	-5.06	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	46	PLXND1,PTPN6,ANTXR2,ZFP36L1,DOCK2,ARAP1,AKAP13,BMP2K,ME1,ITGAL,TLN1,SLC9A7,PTPN12,HCK,ITGAV
6.471e-03	-5.04	negative regulation of cellular process	biological process	GO:0048523	5320	23	18204	49	ITGAV,DAB2,ARHGEF18,ZFP36L1,ARHGAP24,SH2B3,PTPN12,SPI1,ITM2B,PLXND1,ARAP1,HCK,TMSB4X,ELF4,PTGIR,RXRA,CCND2,RBPJ,BTG1,PTPN6,DOCK8,DNM2,CD74
6.527e-03	-5.03	regulation of leukocyte degranulation	biological process	GO:0043300	45	2	18204	49	SPI1,ITGB2
6.527e-03	-5.03	regulation of type I interferon-mediated signaling pathway	biological process	GO:0060338	45	2	18204	49	RBM47,PTPN6
6.550e-03	-5.03	phosphatidylinositol binding	molecular function	GO:0035091	276	4	18094	49	TLN1,WDFY3,ARAP1,DNM2
6.569e-03	-5.03	response to chemical	biological process	GO:0042221	3743	18	18204	49	RXRA,PTGIR,CD68,GAB1,DOCK2,PTPN6,DOCK8,CD74,ZFP36L1,DAB2,ITGAV,SPI1,SH2B3,HCK,TMSB4X,PREX1,ITGB2,ME1
6.588e-03	-5.02	positive regulation of small molecule metabolic process	biological process	GO:0062013	142	3	18204	49	DAB2,TMSB4X,CD74
6.624e-03	-5.02	LAG1, DNA binding domain	gene3d domains	2.60.40.1450	2	1	14470	48	RBPJ
6.624e-03	-5.02	regulation of cell activation	biological process	GO:0050865	630	6	18204	49	ZFP36L1,DOCK8,SPI1,PTPN6,CD74,SH2B3
6.624e-03	-5.02	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	5	19454	50	ITGAV,GAB1,DAB2,EHD4,LRMDA
6.660e-03	-5.01	positive regulation of leukocyte cell-cell adhesion	biological process	GO:1903039	279	4	18204	49	PTPN6,CD74,ITGB2,DOCK8
6.743e-03	-5.00	PFN1 (profilin 1)	protein interactions	5216	466	5	19454	50	AKAP13,ARHGAP24,SEPTIN9,DOCK8,DNM2
6.772e-03	-4.99	FES (FES proto-oncogene, tyrosine kinase)	protein interactions	2242	48	2	19454	50	FKBP5,GAB1
6.812e-03	-4.99	receptor clustering	biological process	GO:0043113	46	2	18204	49	ITGAL,ITGB2
6.812e-03	-4.99	endodermal cell differentiation	biological process	GO:0035987	46	2	18204	49	ITGAV,ITGB2
6.863e-03	-4.98	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	30	16828	46	EHD4,AKAP13,FKBP5,BTG1,ZFP36L1,DOCK2,MYO1F,ANTXR2,STAB1,HCK,SLC9A7,TLN1,PREX1,PTGIR,ITM2B,DNM2,RXRA,BMP2K,HEPHL1,ELF4,WDFY3,DOCK8,PLXND1,GAB1,MCOLN2,PTPN12,ITGAL,ME1,RGL1,SH2B3
6.937e-03	-4.97	regulation of cell migration	biological process	GO:0030334	1061	8	18204	49	ITGAV,DAB2,GAB1,DOCK8,PLXND1,PREX1,TMSB4X,CD74
7.049e-03	-4.95	HBZ (hemoglobin subunit zeta)	protein interactions	3050	49	2	19454	50	DOCK8,ARHGAP24
7.056e-03	-4.95	positive regulation of cell communication	biological process	GO:0010647	1792	11	18204	49	AKAP13,CD74,RXRA,PTPN6,RBPJ,DISC1,DAB2,BMP2K,ITGAV,SPI1,RBM47
7.103e-03	-4.95	regulation of erythrocyte differentiation	biological process	GO:0045646	47	2	18204	49	SPI1,ZFP36L1
7.103e-03	-4.95	labyrinthine layer development	biological process	GO:0060711	47	2	18204	49	ZFP36L1,RBPJ
7.103e-03	-4.95	T cell selection	biological process	GO:0045058	47	2	18204	49	DOCK2,CD74
7.111e-03	-4.95	positive regulation of Wnt signaling pathway	biological process	GO:0030177	146	3	18204	49	RBPJ,DAB2,DISC1
7.116e-03	-4.95	VWA	pfam domains	PF00092	46	2	17795	49	ANTXR2,ITGAL
7.186e-03	-4.94	phosphotyrosine residue binding	molecular function	GO:0001784	47	2	18094	49	PTPN6,HCK
7.263e-03	-4.92	RPL37 (ribosomal protein L37)	protein interactions	6167	154	3	19454	50	HCK,PTPN12,PTPN6
7.263e-03	-4.92	JAK2 (Janus kinase 2)	protein interactions	3717	154	3	19454	50	SH2B3,PTPN12,PTPN6
7.317e-03	-4.92	Fc gamma R-mediated phagocytosis	KEGG pathways	hsa04666	90	3	7161	32	DNM2,HCK,DOCK2
7.317e-03	-4.92	Fc gamma R-mediated phagocytosis	KEGG pathways	ko04666	90	3	7161	32	DOCK2,HCK,DNM2
7.330e-03	-4.92	WNK3 (WNK lysine deficient protein kinase 3)	protein interactions	65267	50	2	19454	50	BMP2K,ARHGAP24
7.412e-03	-4.90	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	9	16828	46	PTPN12,TFEB,STAB1,FKBP5,DISC1,RBM47,DOCK2,DOCK8,ITGB2
7.570e-03	-4.88	PPIB (peptidylprolyl isomerase B)	protein interactions	5479	303	4	19454	50	DOCK8,PREX1,DNM2,ARHGAP24
7.572e-03	-4.88	positive regulation of cell development	biological process	GO:0010720	458	5	18204	49	CD74,SPI1,PLXND1,DISC1,ZFP36L1
7.587e-03	-4.88	extracellular exosome	cellular component	GO:0070062	2175	12	19108	49	CD74,DNM2,DOCK2,ITM2B,PTPN6,ITGAL,ARHGEF18,ITGB2,TLN1,ITGAV,FKBP5,EHD4
7.598e-03	-4.88	SH2	prosite domains	PS50001	107	3	12186	46	PTPN6,SH2B3,HCK
7.617e-03	-4.88	APLP1 (amyloid beta precursor like protein 1)	protein interactions	333	51	2	19454	50	TMSB4X,DAB2
7.658e-03	-4.87	placenta development	biological process	GO:0001890	150	3	18204	49	TFEB,ZFP36L1,RBPJ
7.674e-03	-4.87	MAML1-RBP-Jkappa- ICN1 complex	cellular component	GO:0002193	3	1	19108	49	RBPJ
7.674e-03	-4.87	alphav-beta3 integrin-HMGB1 complex	cellular component	GO:0035868	3	1	19108	49	ITGAV
7.674e-03	-4.87	cyclin D2-CDK4 complex	cellular component	GO:0097129	3	1	19108	49	CCND2
7.674e-03	-4.87	alphav-beta3 integrin-PKCalpha complex	cellular component	GO:0035866	3	1	19108	49	ITGAV
7.674e-03	-4.87	integrin alphav-beta3 complex	cellular component	GO:0034683	3	1	19108	49	ITGAV
7.691e-03	-4.87	CDCP2 (CUB domain containing protein 2)	protein interactions	200008	3	1	19454	50	EHD4
7.691e-03	-4.87	ZNF682 (zinc finger protein 682)	protein interactions	91120	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	SIGLEC11 (sialic acid binding Ig like lectin 11)	protein interactions	114132	3	1	19454	50	PTPN6
7.691e-03	-4.87	ZNF506 (zinc finger protein 506)	protein interactions	440515	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	Srr (serine racemase)	protein interactions	27364	3	1	19454	50	DISC1
7.691e-03	-4.87	Grip1 (glutamate receptor interacting protein 1)	protein interactions	74053	3	1	19454	50	RXRA
7.691e-03	-4.87	ZNF540 (zinc finger protein 540)	protein interactions	163255	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	HERC2P2 (HERC2 pseudogene 2)	protein interactions	400322	3	1	19454	50	DISC1
7.691e-03	-4.87	ZNF716 (zinc finger protein 716)	protein interactions	441234	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	ZNF257 (zinc finger protein 257)	protein interactions	113835	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	NKX6-1 (NK6 homeobox 1)	protein interactions	4825	3	1	19454	50	RBPJ
7.691e-03	-4.87	Myo6 (myosin VI)	protein interactions	315840	3	1	19454	50	DAB2
7.699e-03	-4.87	Signal Transduction	REACTOME pathways	R-HSA-162582	2547	16	10285	36	PTPN6,RBPJ,ARAP1,GAB1,ARHGAP45,PTGIR,ARHGAP24,SH2B3,PTPN12,ARHGEF18,TLN1,AKAP13,DNM2,ITGAV,PREX1,RXRA
7.700e-03	-4.87	platelet aggregation	biological process	GO:0070527	49	2	18204	49	PTPN6,TLN1
7.790e-03	-4.85	molecular sequestering activity	molecular function	GO:0140313	49	2	18094	49	TMSB4X,SPI1
7.816e-03	-4.85	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	38	16828	46	ANTXR2,RBM47,ZFP36L1,DOCK2,MYO1F,ARAP1,DAB2,ARHGAP24,EHD4,AKAP13,RBPJ,ARHGEF18,FKBP5,DNM2,RXRA,ITGB2,SLC9A7,TLN1,PREX1,PTGIR,HCK,TFEB,STAB1,ITGAV,WDFY3,DOCK8,ELF4,HEPHL1,CD68,BMP2K,RGL1,SH2B3,ME1,ITGAL,SPI1,PTPN12,MCOLN2,GAB1
7.857e-03	-4.85	Transcriptional misregulation in cancer	KEGG pathways	ko05202	179	4	7161	32	CCND2,RXRA,BMP2K,SPI1
7.857e-03	-4.85	Transcriptional misregulation in cancer	KEGG pathways	hsa05202	179	4	7161	32	SPI1,BMP2K,CCND2,RXRA
7.890e-03	-4.84	negative regulation of defense response	biological process	GO:0031348	293	4	18204	49	HCK,TMSB4X,ELF4,PTPN6
7.928e-03	-4.84	COG6 (component of oligomeric golgi complex 6)	protein interactions	57511	159	3	19454	50	CD68,TMSB4X,DOCK8
7.941e-03	-4.84	regulation of actin polymerization or depolymerization	biological process	GO:0008064	152	3	18204	49	PREX1,TMSB4X,HCK
7.941e-03	-4.84	regulation of lipid transport	biological process	GO:0032368	152	3	18204	49	DAB2,RXRA,ITGAV
7.957e-03	-4.83	protein domain specific binding	molecular function	GO:0019904	651	6	18094	49	PTPN6,TLN1,RXRA,PTPN12,PLXND1,DNM2
8.007e-03	-4.83	antigen processing and presentation of exogenous antigen	biological process	GO:0019884	50	2	18204	49	DNM2,CD74
8.054e-03	-4.82	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	biological process	GO:0086023	3	1	18204	49	AKAP13
8.054e-03	-4.82	regulation of macrophage migration inhibitory factor signaling pathway	biological process	GO:2000446	3	1	18204	49	CD74
8.054e-03	-4.82	blood vessel endothelial cell fate commitment	biological process	GO:0060846	3	1	18204	49	RBPJ
8.054e-03	-4.82	positive regulation of aldosterone secretion	biological process	GO:2000860	3	1	18204	49	DAB2
8.054e-03	-4.82	positive regulation of intracellular mRNA localization	biological process	GO:1904582	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	positive regulation of aldosterone metabolic process	biological process	GO:0032346	3	1	18204	49	DAB2
8.054e-03	-4.82	positive regulation of mineralocorticoid secretion	biological process	GO:2000857	3	1	18204	49	DAB2
8.054e-03	-4.82	proepicardium development	biological process	GO:0003342	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	cellular response to raffinose	biological process	GO:0097403	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	positive regulation of proton-transporting ATP synthase activity, rotational mechanism	biological process	GO:1905273	3	1	18204	49	TMSB4X
8.054e-03	-4.82	leukocyte migration involved in immune response	biological process	GO:0002522	3	1	18204	49	HCK
8.054e-03	-4.82	response to raffinose	biological process	GO:1901545	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	endothelial to hematopoietic transition	biological process	GO:0098508	3	1	18204	49	SPI1
8.054e-03	-4.82	myeloid dendritic cell activation involved in immune response	biological process	GO:0002277	3	1	18204	49	DOCK2
8.054e-03	-4.82	pyramidal neuron migration to cerebral cortex	biological process	GO:0021852	3	1	18204	49	DISC1
8.054e-03	-4.82	positive regulation of antifungal innate immune response	biological process	GO:1905036	3	1	18204	49	SPI1
8.054e-03	-4.82	regulation of myeloid progenitor cell differentiation	biological process	GO:1905453	3	1	18204	49	SPI1
8.054e-03	-4.82	blood vessel endothelial cell fate specification	biological process	GO:0097101	3	1	18204	49	RBPJ
8.054e-03	-4.82	membrane raft polarization	biological process	GO:0001766	3	1	18204	49	DOCK2
8.054e-03	-4.82	positive regulation of aldosterone biosynthetic process	biological process	GO:0032349	3	1	18204	49	DAB2
8.054e-03	-4.82	positive regulation of clathrin-dependent endocytosis	biological process	GO:2000370	3	1	18204	49	DAB2
8.054e-03	-4.82	regulation of proton-transporting ATP synthase activity, rotational mechanism	biological process	GO:1905271	3	1	18204	49	TMSB4X
8.054e-03	-4.82	regulation of Golgi lumen acidification	biological process	GO:1905526	3	1	18204	49	SLC9A7
8.054e-03	-4.82	septum transversum development	biological process	GO:0003343	3	1	18204	49	ZFP36L1
8.054e-03	-4.82	monocyte homeostasis	biological process	GO:0035702	3	1	18204	49	SH2B3
8.077e-03	-4.82	myeloid cell differentiation	biological process	GO:0030099	295	4	18204	49	SPI1,PTPN6,RBPJ,SH2B3
8.078e-03	-4.82	Anthrax_toxin_rcpt_extracel	interpro domains	IPR008400	3	1	18521	50	ANTXR2
8.078e-03	-4.82	PTN12/18/22	interpro domains	IPR047170	3	1	18521	50	PTPN12
8.078e-03	-4.82	Malic_N_dom_sf	interpro domains	IPR037062	3	1	18521	50	ME1
8.078e-03	-4.82	Malic_OxRdtase	interpro domains	IPR001891	3	1	18521	50	ME1
8.078e-03	-4.82	Malic_NAD-bd	interpro domains	IPR012302	3	1	18521	50	ME1
8.078e-03	-4.82	ITM2	interpro domains	IPR040145	3	1	18521	50	ITM2B
8.078e-03	-4.82	FYB1/2-like	interpro domains	IPR043443	3	1	18521	50	FYB1
8.078e-03	-4.82	LAMP_CS	interpro domains	IPR018134	3	1	18521	50	CD68
8.078e-03	-4.82	Mucolipin	interpro domains	IPR039031	3	1	18521	50	MCOLN2
8.078e-03	-4.82	C2_Dock-C	interpro domains	IPR037808	3	1	18521	50	DOCK8
8.078e-03	-4.82	MiT/TFE_N	interpro domains	IPR031867	3	1	18521	50	TFEB
8.078e-03	-4.82	RII-bd_1	interpro domains	IPR018459	3	1	18521	50	AKAP13
8.078e-03	-4.82	FERM_f0	interpro domains	IPR032425	3	1	18521	50	TLN1
8.078e-03	-4.82	Phe_ZIP	interpro domains	IPR015012	3	1	18521	50	SH2B3
8.078e-03	-4.82	hSH3	interpro domains	IPR029294	3	1	18521	50	FYB1
8.078e-03	-4.82	SH2B	interpro domains	IPR030523	3	1	18521	50	SH2B3
8.078e-03	-4.82	NHE-6/7/9	interpro domains	IPR002090	3	1	18521	50	SLC9A7
8.078e-03	-4.82	Malic_enzyme_CS	interpro domains	IPR015884	3	1	18521	50	ME1
8.078e-03	-4.82	RhoGAP_ARAP	interpro domains	IPR037858	3	1	18521	50	ARAP1
8.078e-03	-4.82	TF_Elf_N	interpro domains	IPR022084	3	1	18521	50	ELF4
8.078e-03	-4.82	MCLN_ECD	interpro domains	IPR049134	3	1	18521	50	MCOLN2
8.078e-03	-4.82	Phe_ZIP_sf	interpro domains	IPR036290	3	1	18521	50	SH2B3
8.078e-03	-4.82	Malic_N_dom	interpro domains	IPR012301	3	1	18521	50	ME1
8.078e-03	-4.82	ZFP36-like	interpro domains	IPR045877	3	1	18521	50	ZFP36L1
8.103e-03	-4.82	vitamin D response element binding	molecular function	GO:0070644	3	1	18094	49	RXRA
8.103e-03	-4.82	DNA binding domain binding	molecular function	GO:0050692	3	1	18094	49	RXRA
8.103e-03	-4.82	malate dehydrogenase (decarboxylating) (NADP+) activity	molecular function	GO:0004473	3	1	18094	49	ME1
8.129e-03	-4.81	positive regulation of hydrolase activity	biological process	GO:0051345	466	5	18204	49	ARAP1,ARHGAP45,DOCK8,ARHGAP24,PREX1
8.161e-03	-4.81	molecular function regulator activity	molecular function	GO:0098772	2079	12	18094	49	ARAP1,DOCK2,PREX1,ARHGAP24,BMP2K,RGL1,DOCK8,PTGIR,ARHGAP45,AKAP13,CCND2,ARHGEF18
8.238e-03	-4.80	Malic_M	pfam domains	PF03949	3	1	17795	49	ME1
8.238e-03	-4.80	Elf-1_N	pfam domains	PF12310	3	1	17795	49	ELF4
8.238e-03	-4.80	Anth_Ig	pfam domains	PF05587	3	1	17795	49	ANTXR2
8.238e-03	-4.80	hSH3	pfam domains	PF14603	3	1	17795	49	FYB1
8.238e-03	-4.80	RII_binding_1	pfam domains	PF10522	3	1	17795	49	AKAP13
8.238e-03	-4.80	MCLN_ECD	pfam domains	PF21381	3	1	17795	49	MCOLN2
8.238e-03	-4.80	MITF_TFEB_C_3_N	pfam domains	PF15951	3	1	17795	49	TFEB
8.238e-03	-4.80	FERM_f0	pfam domains	PF16511	3	1	17795	49	TLN1
8.238e-03	-4.80	malic	pfam domains	PF00390	3	1	17795	49	ME1
8.238e-03	-4.80	Phe_ZIP	pfam domains	PF08916	3	1	17795	49	SH2B3
8.343e-03	-4.79	KLRC1 (killer cell lectin like receptor C1)	protein interactions	3821	162	3	19454	50	PTPN6,WDFY3,DNM2
8.373e-03	-4.78	ACTN1 (actinin alpha 1)	protein interactions	87	312	4	19454	50	TLN1,PTPN6,DISC1,ARHGAP24
8.377e-03	-4.78	regulation of actin filament length	biological process	GO:0030832	155	3	18204	49	TMSB4X,PREX1,HCK
8.421e-03	-4.78	BTD	smart domains	SM01268	2	1	9717	41	RBPJ
8.421e-03	-4.78	LAG1_DNAbind	smart domains	SM01267	2	1	9717	41	RBPJ
8.484e-03	-4.77	IKBIP (IKBKB interacting protein)	protein interactions	121457	163	3	19454	50	DISC1,ANTXR2,DNM2
8.497e-03	-4.77	NONO (non-POU domain containing octamer binding)	protein interactions	4841	493	5	19454	50	ARHGAP24,RXRA,RBPJ,SPI1,DAB2
8.507e-03	-4.77	EPM2A (EPM2A glucan phosphatase, laforin)	protein interactions	7957	54	2	19454	50	FKBP5,PREX1
8.523e-03	-4.77	YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon)	protein interactions	7531	1150	8	19454	50	SH2B3,ARHGAP45,TFEB,GAB1,DISC1,ZFP36L1,AKAP13,CD74
8.536e-03	-4.76	RA	prosite domains	PS50200	37	2	12186	46	ARAP1,RGL1
8.536e-03	-4.76	TYR_PHOSPHATASE_PTP	prosite domains	PS50055	37	2	12186	46	PTPN12,PTPN6
8.550e-03	-4.76	PRTYPHPHTASE	prints domains	PR00700	37	2	5227	20	PTPN6,PTPN12
8.578e-03	-4.76	regulation of immune system process	biological process	GO:0002682	1584	10	18204	49	CD74,FYB1,DOCK8,HCK,ITGB2,SPI1,RBM47,PTPN6,CD68,ZFP36L1
8.638e-03	-4.75	ERK1 and ERK2 cascade	biological process	GO:0070371	52	2	18204	49	ITGAV,ZFP36L1
8.638e-03	-4.75	iron ion transport	biological process	GO:0006826	52	2	18204	49	DNM2,HEPHL1
8.675e-03	-4.75	negative regulation of cytoskeleton organization	biological process	GO:0051494	157	3	18204	49	TMSB4X,ARHGEF18,ARAP1
8.710e-03	-4.74	growth cone	cellular component	GO:0030426	165	3	19108	49	PREX1,DNM2,DISC1
8.761e-03	-4.74	secretory granule membrane	cellular component	GO:0030667	317	4	19108	49	ITGAL,CD68,ITGAV,ITGB2
8.793e-03	-4.73	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	33	16828	46	DOCK2,MYO1F,ZFP36L1,PTPN6,RBM47,AKAP13,EHD4,ARHGEF18,RBPJ,DAB2,BTG1,ARHGAP24,RXRA,ITGAV,TFEB,HCK,STAB1,SLC9A7,TLN1,PTGIR,PREX1,WDFY3,DOCK8,PLXND1,HEPHL1,ELF4,ITGAL,ME1,RGL1,GAB1,MCOLN2,PTPN12,CCND2
8.926e-03	-4.72	CBL (Cbl proto-oncogene)	protein interactions	867	499	5	19454	50	ITGAV,FYB1,ARHGAP45,HCK,PTPN6
9.053e-03	-4.70	intracellular non-membrane-bounded organelle	cellular component	GO:0043232	5729	23	19108	49	AKAP13,SEPTIN9,DAB2,RBPJ,DNM2,TFEB,MYO1F,PTPN12,HCK,PTPN6,DISC1,FYB1,WDFY3,TMSB4X,ARHGAP24,SPI1,TLN1,RXRA,ELF4,DOCK2,ZFP36L1,CCND2,ARHGEF18
9.094e-03	-4.70	non-membrane-bounded organelle	cellular component	GO:0043228	5731	23	19108	49	TFEB,MYO1F,DAB2,DNM2,RBPJ,AKAP13,SEPTIN9,DISC1,PTPN6,PTPN12,HCK,SPI1,ARHGAP24,WDFY3,TMSB4X,FYB1,ZFP36L1,CCND2,ARHGEF18,DOCK2,RXRA,ELF4,TLN1
9.125e-03	-4.70	LETMD1 (LETM1 domain containing 1)	protein interactions	25875	56	2	19454	50	MCOLN2,HCK
9.125e-03	-4.70	TEDC1 (tubulin epsilon and delta complex 1)	protein interactions	283643	56	2	19454	50	FKBP5,DISC1
9.140e-03	-4.70	PPARA activates gene expression	REACTOME pathways	R-HSA-1989781	124	3	10285	36	ME1,RXRA,RGL1
9.145e-03	-4.69	secretory granule lumen	cellular component	GO:0034774	321	4	19108	49	TMSB4X,ARHGAP45,DOCK2,PTPN6
9.209e-03	-4.69	SH2	smart domains	SM00252	103	3	9717	41	SH2B3,HCK,PTPN6
9.212e-03	-4.69	KLK10 (kallikrein related peptidase 10)	protein interactions	5655	168	3	19454	50	PTPN6,MYO1F,ITGB2
9.231e-03	-4.69	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	4	19454	50	DNM2,TLN1,SEPTIN9,TMSB4X
9.290e-03	-4.68	negative regulation of supramolecular fiber organization	biological process	GO:1902904	161	3	18204	49	ARAP1,TMSB4X,ARHGEF18
9.301e-03	-4.68	regulation of response to external stimulus	biological process	GO:0032101	1116	8	18204	49	ELF4,CD74,TMSB4X,HCK,SH2B3,SPI1,PTPN6,RBM47
9.361e-03	-4.67	H2BC5 (H2B clustered histone 5)	protein interactions	3017	169	3	19454	50	ARHGAP24,DNM2,TLN1
9.378e-03	-4.67	organelle membrane	cellular component	GO:0031090	3742	17	19108	49	STAB1,ANTXR2,WDFY3,EHD4,DNM2,ITM2B,DAB2,CD68,TFEB,MCOLN2,ITGB2,ITGAV,ARAP1,CD74,SLC9A7,CCND2,ITGAL
9.442e-03	-4.66	ICAM2 (intercellular adhesion molecule 2)	protein interactions	3384	57	2	19454	50	ITM2B,ITGB2
9.442e-03	-4.66	PRKCQ (protein kinase C theta)	protein interactions	5588	57	2	19454	50	FKBP5,FYB1
9.442e-03	-4.66	PTPRC (protein tyrosine phosphatase receptor type C)	protein interactions	5788	57	2	19454	50	PTPN6,ITGAL
9.442e-03	-4.66	RBSN (rabenosyn, RAB effector)	protein interactions	64145	57	2	19454	50	DISC1,EHD4
9.446e-03	-4.66	site of polarized growth	cellular component	GO:0030427	170	3	19108	49	DISC1,DNM2,PREX1
9.513e-03	-4.66	PLOD2 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 2)	protein interactions	5352	170	3	19454	50	PTPN12,TLN1,ARHGAP24
9.592e-03	-4.65	regulation of cell motility	biological process	GO:2000145	1122	8	18204	49	PREX1,TMSB4X,DOCK8,PLXND1,CD74,DAB2,ITGAV,GAB1
9.619e-03	-4.64	SH3	prosite domains	PS50002	222	4	12186	46	MYO1F,FYB1,DOCK2,HCK
9.623e-03	-4.64	cellular response to chemical stimulus	biological process	GO:0070887	2411	13	18204	49	PTPN6,GAB1,RXRA,CD68,CD74,DOCK8,SPI1,SH2B3,ZFP36L1,PREX1,TMSB4X,ITGB2,HCK
9.625e-03	-4.64	morphogenesis of an epithelial sheet	biological process	GO:0002011	55	2	18204	49	ARHGAP24,ITGAV
9.625e-03	-4.64	neutrophil chemotaxis	biological process	GO:0030593	55	2	18204	49	PREX1,ITGB2
9.641e-03	-4.64	cytoplasmic vesicle lumen	cellular component	GO:0060205	326	4	19108	49	ARHGAP45,TMSB4X,PTPN6,DOCK2
9.674e-03	-4.64	RHOH (ras homolog family member H)	protein interactions	399	509	5	19454	50	ITGAV,PREX1,DAB2,EHD4,ITM2B
9.731e-03	-4.63	PXN (paxillin)	protein interactions	5829	326	4	19454	50	HCK,PTPN12,TLN1,ITGAV
9.743e-03	-4.63	vesicle lumen	cellular component	GO:0031983	327	4	19108	49	TMSB4X,ARHGAP45,PTPN6,DOCK2
9.755e-03	-4.63	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	REACTOME pathways	R-HSA-400206	127	3	10285	36	ME1,RXRA,RGL1
9.763e-03	-4.63	LRCH1 (leucine rich repeats and calponin homology domain containing 1)	protein interactions	23143	58	2	19454	50	DOCK8,HEPHL1
9.763e-03	-4.63	Sec24c (SEC24 homolog C, COPII coat complex component)	protein interactions	218811	58	2	19454	50	BMP2K,DAB2
9.763e-03	-4.63	PPWD1 (peptidylprolyl isomerase domain and WD repeat containing 1)	protein interactions	23398	58	2	19454	50	ME1,FKBP5
9.811e-03	-4.62	tube morphogenesis	biological process	GO:0035239	685	6	18204	49	ZFP36L1,ARHGAP24,ITGAV,GAB1,RBPJ,PLXND1
9.819e-03	-4.62	ROCK1 (Rho associated coiled-coil containing protein kinase 1)	protein interactions	6093	172	3	19454	50	TLN1,ARHGAP24,GAB1
9.919e-03	-4.61	-	gene3d domains	6.10.140.110	3	1	14470	48	SH2B3
9.919e-03	-4.61	Malic enzyme, N-terminal domain	gene3d domains	3.40.50.10380	3	1	14470	48	ME1
9.950e-03	-4.61	CAV1 (caveolin 1)	protein interactions	857	719	6	19454	50	PTPN6,TMSB4X,SEPTIN9,ITM2B,GAB1,ITGAV
9.964e-03	-4.61	modulation by symbiont of entry into host	biological process	GO:0052372	56	2	18204	49	ITGAV,CD74
9.964e-03	-4.61	leukocyte cell-cell adhesion	biological process	GO:0007159	56	2	18204	49	ITGB2,ITGAL
9.964e-03	-4.61	endoderm formation	biological process	GO:0001706	56	2	18204	49	ITGAV,ITGB2
9.964e-03	-4.61	negative regulation of leukocyte apoptotic process	biological process	GO:2000107	56	2	18204	49	DOCK8,CD74
9.975e-03	-4.61	ALDH18A1 (aldehyde dehydrogenase 18 family member A1)	protein interactions	5832	173	3	19454	50	DOCK8,PREX1,ARHGAP24
9.975e-03	-4.61	RARA (retinoic acid receptor alpha)	protein interactions	5914	173	3	19454	50	RXRA,BTG1,SPI1
1.004e-02	-4.60	NCOR1 (nuclear receptor corepressor 1)	protein interactions	9611	329	4	19454	50	CCND2,RBPJ,RXRA,ITGAV
1.005e-02	-4.60	tube development	biological process	GO:0035295	903	7	18204	49	PLXND1,GAB1,PTPN6,RBPJ,ZFP36L1,ARHGAP24,ITGAV
1.007e-02	-4.60	SH3	smart domains	SM00326	202	4	9717	41	FYB1,HCK,DOCK2,MYO1F
1.007e-02	-4.60	regulation of cell differentiation	biological process	GO:0045595	1622	10	18204	49	CD74,PLXND1,DISC1,RBPJ,SPI1,BTG1,PTPN6,ITGAV,DAB2,ZFP36L1
1.009e-02	-4.60	CD82 (CD82 molecule)	protein interactions	3732	59	2	19454	50	ITGB2,ITGAL
1.013e-02	-4.59	KAT2A (lysine acetyltransferase 2A)	protein interactions	2648	174	3	19454	50	RBPJ,CCND2,ELF4
1.013e-02	-4.59	phospholipid binding	molecular function	GO:0005543	489	5	18094	49	DNM2,PREX1,WDFY3,TLN1,ARAP1
1.017e-02	-4.59	RHOA (ras homolog family member A)	protein interactions	387	1186	8	19454	50	DNM2,PREX1,AKAP13,GAB1,ITGAV,ARHGEF18,DAB2,PTPN12
1.022e-02	-4.58	alphav-beta3 integrin-IGF-1-IGF1R complex	cellular component	GO:0035867	4	1	19108	49	ITGAV
1.022e-02	-4.58	central region of growth cone	cellular component	GO:0090724	4	1	19108	49	DISC1
1.023e-02	-4.58	positive regulation of cell differentiation	biological process	GO:0045597	906	7	18204	49	DISC1,PLXND1,CD74,ZFP36L1,DAB2,BTG1,SPI1
1.024e-02	-4.58	DMP1 (dentin matrix acidic phosphoprotein 1)	protein interactions	1758	4	1	19454	50	CCND2
1.024e-02	-4.58	ZNF749 (zinc finger protein 749)	protein interactions	388567	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	Fndc5 (fibronectin type III domain containing 5)	protein interactions	384061	4	1	19454	50	ITGAV
1.024e-02	-4.58	H1-10-AS1 (H1-10 antisense RNA 1)	protein interactions	339942	4	1	19454	50	PTPN6
1.024e-02	-4.58	ZNF615 (zinc finger protein 615)	protein interactions	284370	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	ZNF879 (zinc finger protein 879)	protein interactions	345462	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	MGAT3 (beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase)	protein interactions	4248	4	1	19454	50	DISC1
1.024e-02	-4.58	Map6 (microtubule-associated protein 6)	protein interactions	29457	4	1	19454	50	PLXND1
1.024e-02	-4.58	FBXO41 (F-box protein 41)	protein interactions	150726	4	1	19454	50	DISC1
1.030e-02	-4.58	cellular response to growth factor stimulus	biological process	GO:0071363	494	5	18204	49	ZFP36L1,DAB2,EHD4,PTPN12,GAB1
1.031e-02	-4.57	regulation of myeloid leukocyte mediated immunity	biological process	GO:0002886	57	2	18204	49	SPI1,ITGB2
1.031e-02	-4.57	regulation of lymphocyte apoptotic process	biological process	GO:0070228	57	2	18204	49	DOCK8,CD74
1.033e-02	-4.57	thyroid	COSMIC cancer mutations	thyroid	9867	35	16828	46	ITGAV,STAB1,TFEB,PREX1,PTGIR,SLC9A7,TLN1,ITGB2,RXRA,DNM2,ARHGEF18,FKBP5,RBPJ,CD74,EHD4,AKAP13,DAB2,ARAP1,ZFP36L1,DOCK2,MYO1F,RBM47,ANTXR2,GAB1,MCOLN2,SPI1,ITGAL,RGL1,SH2B3,BMP2K,HEPHL1,ELF4,WDFY3,DOCK8,PLXND1
1.035e-02	-4.57	salivary_gland-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma-adenoid_cystic_carcinoma	488	5	16828	46	TLN1,SLC9A7,ITM2B,ZFP36L1,DOCK8
1.042e-02	-4.56	MITF (melanocyte inducing transcription factor)	protein interactions	4286	60	2	19454	50	SPI1,TFEB
1.054e-02	-4.55	PTPc	smart domains	SM00194	37	2	9717	41	PTPN12,PTPN6
1.061e-02	-4.55	PIP (prolactin induced protein)	protein interactions	5304	177	3	19454	50	SPI1,RBM47,ARHGAP24
1.064e-02	-4.54	regulation of anatomical structure size	biological process	GO:0090066	498	5	18204	49	DISC1,DNM2,TMSB4X,HCK,PREX1
1.070e-02	-4.54	negative regulation of apoptotic process	biological process	GO:0043066	914	7	18204	49	PLXND1,DOCK8,HCK,CD74,ITGAV,CCND2,DAB2
1.072e-02	-4.54	negative regulation of mast cell activation involved in immune response	biological process	GO:0033007	4	1	18204	49	PTPN6
1.072e-02	-4.54	regulation of mature B cell apoptotic process	biological process	GO:0002905	4	1	18204	49	CD74
1.072e-02	-4.54	inner ear receptor cell fate commitment	biological process	GO:0060120	4	1	18204	49	RBPJ
1.072e-02	-4.54	endothelial cell fate specification	biological process	GO:0060847	4	1	18204	49	RBPJ
1.072e-02	-4.54	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	biological process	GO:2000587	4	1	18204	49	PTPN12
1.072e-02	-4.54	club cell differentiation	biological process	GO:0060486	4	1	18204	49	RBPJ
1.072e-02	-4.54	positive regulation of neutrophil degranulation	biological process	GO:0043315	4	1	18204	49	ITGB2
1.072e-02	-4.54	auditory receptor cell fate commitment	biological process	GO:0009912	4	1	18204	49	RBPJ
1.072e-02	-4.54	positive regulation of establishment of T cell polarity	biological process	GO:1903905	4	1	18204	49	DOCK8
1.072e-02	-4.54	negative regulation of dendritic cell antigen processing and presentation	biological process	GO:0002605	4	1	18204	49	CD68
1.072e-02	-4.54	respiratory burst after phagocytosis	biological process	GO:0045728	4	1	18204	49	HCK
1.072e-02	-4.54	dichotomous subdivision of terminal units involved in salivary gland branching	biological process	GO:0060666	4	1	18204	49	PLXND1
1.072e-02	-4.54	negative regulation of mature B cell apoptotic process	biological process	GO:0002906	4	1	18204	49	CD74
1.072e-02	-4.54	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	biological process	GO:0002291	4	1	18204	49	ITGAL
1.072e-02	-4.54	positive regulation of steroid hormone biosynthetic process	biological process	GO:0090031	4	1	18204	49	DAB2
1.072e-02	-4.54	positive regulation of microglial cell mediated cytotoxicity	biological process	GO:1904151	4	1	18204	49	SPI1
1.072e-02	-4.54	regulation of intracellular mRNA localization	biological process	GO:1904580	4	1	18204	49	ZFP36L1
1.076e-02	-4.53	FAS1_dom_sf	interpro domains	IPR036378	4	1	18521	50	STAB1
1.076e-02	-4.53	Beta-thymosin	interpro domains	IPR001152	4	1	18521	50	TMSB4X
1.076e-02	-4.53	Cu-oxidase_C	interpro domains	IPR011706	4	1	18521	50	HEPHL1
1.076e-02	-4.53	DUF5600	interpro domains	IPR040990	4	1	18521	50	EHD4
1.076e-02	-4.53	ILWEQ_dom	interpro domains	IPR002558	4	1	18521	50	TLN1
1.076e-02	-4.53	FAS1_domain	interpro domains	IPR000782	4	1	18521	50	STAB1
1.076e-02	-4.53	Gab1-4-like	interpro domains	IPR046355	4	1	18521	50	GAB1
1.076e-02	-4.53	BTG	interpro domains	IPR033332	4	1	18521	50	BTG1
1.076e-02	-4.53	Cu_oxidase_Cu_BS	interpro domains	IPR002355	4	1	18521	50	HEPHL1
1.076e-02	-4.53	Beta-thymosin_sf	interpro domains	IPR038386	4	1	18521	50	TMSB4X
1.076e-02	-4.53	I/LWEQ_dom_sf	interpro domains	IPR035964	4	1	18521	50	TLN1
1.076e-02	-4.53	MiT/TFE_C	interpro domains	IPR021802	4	1	18521	50	TFEB
1.076e-02	-4.53	Retinoid-X_rcpt/HNF4	interpro domains	IPR000003	4	1	18521	50	RXRA
1.076e-02	-4.53	ATF1 (activating transcription factor 1)	protein interactions	466	61	2	19454	50	RBPJ,SPI1
1.076e-02	-4.53	negative regulation of MAPK cascade	biological process	GO:0043409	170	3	18204	49	PTPN6,SH2B3,DAB2
1.078e-02	-4.53	wound healing	biological process	GO:0042060	321	4	18204	49	ARHGAP24,TLN1,ITGAV,PTPN6
1.079e-02	-4.53	malic enzyme activity	molecular function	GO:0004470	4	1	18094	49	ME1
1.079e-02	-4.53	stem cell factor receptor binding	molecular function	GO:0005173	4	1	18094	49	SH2B3
1.079e-02	-4.53	oxaloacetate decarboxylase activity	molecular function	GO:0008948	4	1	18094	49	ME1
1.085e-02	-4.52	extracellular vesicle	cellular component	GO:1903561	2278	12	19108	49	ARHGEF18,ITGAL,DOCK2,DNM2,CD74,PTPN6,ITM2B,EHD4,FKBP5,ITGB2,ITGAV,TLN1
1.089e-02	-4.52	extracellular organelle	cellular component	GO:0043230	2279	12	19108	49	ITGAL,ARHGEF18,ITM2B,PTPN6,CD74,DNM2,DOCK2,FKBP5,EHD4,TLN1,ITGAV,ITGB2
1.089e-02	-4.52	extracellular membrane-bounded organelle	cellular component	GO:0065010	2279	12	19108	49	ITGAV,TLN1,ITGB2,EHD4,FKBP5,PTPN6,ITM2B,DOCK2,DNM2,CD74,ARHGEF18,ITGAL
1.089e-02	-4.52	haematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosis	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-other-idiopathic_erythrocytosis	4	1	16828	46	SH2B3
1.089e-02	-4.52	idiopathic_erythrocytosis	COSMIC cancer mutations	idiopathic_erythrocytosis	4	1	16828	46	SH2B3
1.089e-02	-4.52	CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1)	protein interactions	829	337	4	19454	50	ARAP1,DNM2,DISC1,RXRA
1.089e-02	-4.52	RHBDD1 (rhomboid domain containing 1)	protein interactions	84236	337	4	19454	50	MYO1F,TLN1,ITGB2,MCOLN2
1.094e-02	-4.52	CAP1 (cyclase associated actin cytoskeleton regulatory protein 1)	protein interactions	10487	179	3	19454	50	SEPTIN9,ARHGAP24,FKBP5
1.097e-02	-4.51	Fasciclin	pfam domains	PF02469	4	1	17795	49	STAB1
1.097e-02	-4.51	TPR_6	pfam domains	PF13174	4	1	17795	49	FKBP5
1.097e-02	-4.51	Thymosin	pfam domains	PF01290	4	1	17795	49	TMSB4X
1.097e-02	-4.51	DUF5600	pfam domains	PF18150	4	1	17795	49	EHD4
1.097e-02	-4.51	DUF3371	pfam domains	PF11851	4	1	17795	49	TFEB
1.097e-02	-4.51	I_LWEQ	pfam domains	PF01608	4	1	17795	49	TLN1
1.097e-02	-4.51	Cu-oxidase_2	pfam domains	PF07731	4	1	17795	49	HEPHL1
1.100e-02	-4.51	AP2B1 (adaptor related protein complex 2 subunit beta 1)	protein interactions	163	338	4	19454	50	DAB2,FKBP5,BMP2K,ARHGAP24
1.100e-02	-4.51	ERBB3 (erb-b2 receptor tyrosine kinase 3)	protein interactions	2065	338	4	19454	50	SH2B3,PTPN6,PTPN12,HCK
1.104e-02	-4.51	specific granule lumen	cellular component	GO:0035580	62	2	19108	49	PTPN6,DOCK2
1.122e-02	-4.49	UBA1 (ubiquitin like modifier activating enzyme 1)	protein interactions	7317	340	4	19454	50	ARHGAP24,CCND2,TLN1,DOCK8
1.126e-02	-4.49	regulation of lymphocyte activation	biological process	GO:0051249	505	5	18204	49	ZFP36L1,DOCK8,PTPN6,SPI1,CD74
1.126e-02	-4.49	regulation of phosphate metabolic process	biological process	GO:0019220	1154	8	18204	49	PTPN6,CCND2,DAB2,EHD4,CD74,ME1,ITGB2,TMSB4X
1.127e-02	-4.49	PPP5C (protein phosphatase 5 catalytic subunit)	protein interactions	5536	181	3	19454	50	DISC1,RXRA,FKBP5
1.128e-02	-4.48	LAMP_2	prosite domains	PS00311	3	1	12186	46	CD68
1.128e-02	-4.48	MALIC_ENZYMES	prosite domains	PS00331	3	1	12186	46	ME1
1.128e-02	-4.48	MULTICOPPER_OXIDASE2	prosite domains	PS00080	3	1	12186	46	HEPHL1
1.131e-02	-4.48	regulation of phosphorus metabolic process	biological process	GO:0051174	1155	8	18204	49	DAB2,CCND2,PTPN6,TMSB4X,ITGB2,ME1,CD74,EHD4
1.137e-02	-4.48	positive regulation of cytokine-mediated signaling pathway	biological process	GO:0001961	60	2	18204	49	CD74,RBM47
1.143e-02	-4.47	human chr6q14.2	chromosome location	human chr6q14.2	6	1	26134	50	ME1
1.144e-02	-4.47	MALOXRDTASE	prints domains	PR00072	3	1	5227	20	ME1
1.144e-02	-4.47	NAHEXCHNGR6	prints domains	PR01088	3	1	5227	20	SLC9A7
1.144e-02	-4.47	DDX11 (DEAD/H-box helicase 11)	protein interactions	1663	63	2	19454	50	FKBP5,WDFY3
1.145e-02	-4.47	TOP3B (DNA topoisomerase III beta)	protein interactions	8940	1465	9	19454	50	TLN1,ARAP1,PREX1,WDFY3,PLXND1,SH2B3,TFEB,RBM47,AKAP13
1.145e-02	-4.47	TERF1 (telomeric repeat binding factor 1)	protein interactions	7013	342	4	19454	50	DOCK2,ARHGEF18,ZFP36L1,BMP2K
1.151e-02	-4.46	protein phosphorylated amino acid binding	molecular function	GO:0045309	60	2	18094	49	HCK,PTPN6
1.153e-02	-4.46	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	49	GAB1,PTPN12,ZFP36L1,DAB2,RXRA,CD68,EHD4,ME1,ITGB2
1.160e-02	-4.46	positive regulation of cell-cell adhesion	biological process	GO:0022409	328	4	18204	49	DOCK8,ITGB2,CD74,PTPN6
1.160e-02	-4.46	positive regulation of lymphocyte activation	biological process	GO:0051251	328	4	18204	49	SPI1,PTPN6,CD74,DOCK8
1.161e-02	-4.46	HCK (HCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3055	183	3	19454	50	GAB1,DNM2,HCK
1.161e-02	-4.46	DEK (DEK proto-oncogene)	protein interactions	7913	183	3	19454	50	ARHGAP24,PTPN12,RBPJ
1.161e-02	-4.46	GTF3C4 (general transcription factor IIIC subunit 4)	protein interactions	9329	183	3	19454	50	ARHGAP24,EHD4,RBPJ
1.164e-02	-4.45	regulation of interleukin-6 production	biological process	GO:0032675	175	3	18204	49	CD74,ELF4,PTPN6
1.168e-02	-4.45	INSR (insulin receptor)	protein interactions	3643	344	4	19454	50	PTPN6,PTPN12,GAB1,ITGAV
1.170e-02	-4.45	ruffle	cellular component	GO:0001726	184	3	19108	49	ITGAV,TLN1,ARHGAP45
1.172e-02	-4.45	regulation of leukocyte differentiation	biological process	GO:1902105	329	4	18204	49	ZFP36L1,SPI1,PTPN6,CD74
1.174e-02	-4.44	aorta development	biological process	GO:0035904	61	2	18204	49	RBPJ,PLXND1
1.179e-02	-4.44	LRCH2 (leucine rich repeats and calponin homology domain containing 2)	protein interactions	57631	64	2	19454	50	DOCK8,DOCK2
1.179e-02	-4.44	TPM3 (tropomyosin 3)	protein interactions	7170	345	4	19454	50	FKBP5,RXRA,SEPTIN9,DISC1
1.181e-02	-4.44	Tyr_Pase_cat	interpro domains	IPR003595	61	2	18521	50	PTPN12,PTPN6
1.181e-02	-4.44	C1-like_sf	interpro domains	IPR046349	61	2	18521	50	ARHGAP45,AKAP13
1.182e-02	-4.44	regulation of locomotion	biological process	GO:0040012	1164	8	18204	49	ITGAV,DAB2,GAB1,PLXND1,DOCK8,TMSB4X,PREX1,CD74
1.190e-02	-4.43	circulatory system development	biological process	GO:0072359	933	7	18204	49	AKAP13,PLXND1,ZFP36L1,ARHGAP24,ITGAV,GAB1,RBPJ
1.195e-02	-4.43	SMAP2 (small ArfGAP2)	protein interactions	64744	185	3	19454	50	DAB2,RBM47,BMP2K
1.196e-02	-4.43	regulation of small molecule metabolic process	biological process	GO:0062012	331	4	18204	49	CD74,DAB2,TMSB4X,ME1
1.211e-02	-4.41	regulation of substrate adhesion-dependent cell spreading	biological process	GO:1900024	62	2	18204	49	DAB2,PREX1
1.211e-02	-4.41	positive regulation of myeloid leukocyte differentiation	biological process	GO:0002763	62	2	18204	49	CD74,ZFP36L1
1.215e-02	-4.41	RPS6KA6 (ribosomal protein S6 kinase A6)	protein interactions	27330	65	2	19454	50	RBPJ,RXRA
1.226e-02	-4.40	SH3_2	pfam domains	PF07653	61	2	17795	49	DOCK2,FYB1
1.238e-02	-4.39	EPHA2 (EPH receptor A2)	protein interactions	1969	350	4	19454	50	HCK,CCND2,ITGAV,GAB1
1.250e-02	-4.38	HLA-DRB3 (major histocompatibility complex, class II, DR beta 3)	protein interactions	3125	66	2	19454	50	CD74,ITM2B
1.261e-02	-4.37	Malic_M	smart domains	SM00919	3	1	9717	41	ME1
1.261e-02	-4.37	malic	smart domains	SM01274	3	1	9717	41	ME1
1.263e-02	-4.37	regulation of immune response	biological process	GO:0050776	944	7	18204	49	FYB1,CD74,ITGB2,HCK,SPI1,PTPN6,RBM47
1.276e-02	-4.36	apolipoprotein B mRNA editing enzyme complex	cellular component	GO:0030895	5	1	19108	49	RBM47
1.276e-02	-4.36	alpha-beta T cell receptor complex	cellular component	GO:0042105	5	1	19108	49	PTPN6
1.277e-02	-4.36	negative regulation of programmed cell death	biological process	GO:0043069	946	7	18204	49	CD74,HCK,PLXND1,DOCK8,DAB2,CCND2,ITGAV
1.279e-02	-4.36	ADCY10 (adenylate cyclase 10)	protein interactions	55811	5	1	19454	50	PTGIR
1.279e-02	-4.36	ZNF836 (zinc finger protein 836)	protein interactions	162962	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	Calu (calumenin)	protein interactions	12321	5	1	19454	50	SEPTIN9
1.279e-02	-4.36	ZNF93 (zinc finger protein 93)	protein interactions	81931	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	POU2F3 (POU class 2 homeobox 3)	protein interactions	25833	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	ZNF571 (zinc finger protein 571)	protein interactions	51276	5	1	19454	50	ARHGAP24
1.281e-02	-4.36	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	28	16828	46	CCND2,GAB1,PTPN12,MCOLN2,ME1,SH2B3,RGL1,HEPHL1,TMSB4X,PLXND1,WDFY3,DOCK8,PREX1,SLC9A7,ITGAV,STAB1,TFEB,RXRA,DNM2,ITGB2,BTG1,DAB2,FKBP5,AKAP13,EHD4,DOCK2,ZFP36L1,MYO1F
1.281e-02	-4.36	regulation of hydrolase activity	biological process	GO:0051336	726	6	18204	49	ARHGAP24,ARHGAP45,PREX1,PLXND1,DOCK8,ARAP1
1.286e-02	-4.35	TRIP6 (thyroid hormone receptor interactor 6)	protein interactions	7205	354	4	19454	50	TMSB4X,HCK,TLN1,PTPN6
1.287e-02	-4.35	MIOS (meiosis regulator for oocyte development)	protein interactions	54468	67	2	19454	50	ARHGAP24,RXRA
1.287e-02	-4.35	ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1)	protein interactions	50807	67	2	19454	50	HCK,PTPN12
1.287e-02	-4.35	STX16 (syntaxin 16)	protein interactions	8675	67	2	19454	50	PTPN12,MCOLN2
1.291e-02	-4.35	VIRMA (vir like m6A methyltransferase associated)	protein interactions	25962	2914	14	19454	50	SEPTIN9,PREX1,DNM2,AKAP13,DISC1,PLXND1,TLN1,WDFY3,ITGAV,RGL1,BMP2K,GAB1,RBM47,ARHGEF18
1.291e-02	-4.35	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	27	16828	46	PLXND1,TMSB4X,WDFY3,HEPHL1,ME1,CCND2,PTPN12,MCOLN2,GAB1,PTPN6,DISC1,RBM47,MYO1F,ZFP36L1,DOCK2,ARAP1,AKAP13,RBPJ,ARHGEF18,DNM2,RXRA,ITGB2,TLN1,PREX1,STAB1,HCK,ITGAV
1.312e-02	-4.33	cell-substrate adhesion	biological process	GO:0031589	183	3	18204	49	ITGAV,ITGB2,ITGAL
1.312e-02	-4.33	regulation of lipid localization	biological process	GO:1905952	183	3	18204	49	ITGAV,DAB2,RXRA
1.314e-02	-4.33	response to growth factor	biological process	GO:0070848	525	5	18204	49	PTPN12,EHD4,GAB1,ZFP36L1,DAB2
1.320e-02	-4.33	Single helix bin	gene3d domains	1.20.5.520	4	1	14470	48	TMSB4X
1.320e-02	-4.33	FAS1 domain	gene3d domains	2.30.180.10	4	1	14470	48	STAB1
1.320e-02	-4.33	Talin, central domain	gene3d domains	1.20.1420.10	4	1	14470	48	TLN1
1.324e-02	-4.32	PTOV1 (PTOV1 extended AT-hook containing adaptor protein)	protein interactions	53635	68	2	19454	50	RBPJ,FKBP5
1.324e-02	-4.32	CDKL2 (cyclin dependent kinase like 2)	protein interactions	8999	68	2	19454	50	FKBP5,MYO1F
1.325e-02	-4.32	regulation of biological process involved in symbiotic interaction	biological process	GO:0043903	65	2	18204	49	CD74,ITGAV
1.327e-02	-4.32	response to stress	biological process	GO:0006950	3388	16	18204	49	MCOLN2,CD74,RBPJ,PTPN6,PTGIR,CD68,ITGB2,TLN1,HCK,STAB1,SPI1,ITGAV,ARHGAP24,TFEB,ZFP36L1,ITGAL
1.339e-02	-4.31	negative regulation of Rac protein signal transduction	biological process	GO:0035021	5	1	18204	49	ARHGAP24
1.339e-02	-4.31	regulation of antifungal innate immune response	biological process	GO:1905034	5	1	18204	49	SPI1
1.339e-02	-4.31	regulation of mast cell activation involved in immune response	biological process	GO:0033006	5	1	18204	49	PTPN6
1.339e-02	-4.31	negative regulation of adipose tissue development	biological process	GO:1904178	5	1	18204	49	SPI1
1.339e-02	-4.31	epididymis development	biological process	GO:1905867	5	1	18204	49	PTPN6
1.339e-02	-4.31	regulation of microglial cell mediated cytotoxicity	biological process	GO:1904149	5	1	18204	49	SPI1
1.339e-02	-4.31	membrane tubulation	biological process	GO:0097749	5	1	18204	49	DNM2
1.339e-02	-4.31	negative regulation of lipoprotein metabolic process	biological process	GO:0050748	5	1	18204	49	ITGAV
1.339e-02	-4.31	positive regulation of cell proliferation involved in heart morphogenesis	biological process	GO:2000138	5	1	18204	49	RBPJ
1.339e-02	-4.31	transforming growth factor beta production	biological process	GO:0071604	5	1	18204	49	ITGAV
1.339e-02	-4.31	natural killer cell proliferation	biological process	GO:0001787	5	1	18204	49	ELF4
1.339e-02	-4.31	thrombopoietin-mediated signaling pathway	biological process	GO:0038163	5	1	18204	49	SH2B3
1.339e-02	-4.31	regulation of membrane tubulation	biological process	GO:1903525	5	1	18204	49	DNM2
1.339e-02	-4.31	epidermal cell fate specification	biological process	GO:0009957	5	1	18204	49	RBPJ
1.343e-02	-4.31	Cu_oxidase_CS	interpro domains	IPR033138	5	1	18521	50	HEPHL1
1.343e-02	-4.31	Lysosome-assoc_membr_glycop	interpro domains	IPR002000	5	1	18521	50	CD68
1.343e-02	-4.31	Cu-oxidase-like_N	interpro domains	IPR011707	5	1	18521	50	HEPHL1
1.343e-02	-4.31	Lamp2-like_luminal	interpro domains	IPR048528	5	1	18521	50	CD68
1.343e-02	-4.31	HnRNP_R/Q_splicing_fac	interpro domains	IPR006535	5	1	18521	50	RBM47
1.343e-02	-4.31	EHD_N	interpro domains	IPR031692	5	1	18521	50	EHD4
1.343e-02	-4.31	DOCK_N	interpro domains	IPR032376	5	1	18521	50	DOCK2
1.343e-02	-4.31	DOCK_N_sub1	interpro domains	IPR042455	5	1	18521	50	DOCK2
1.344e-02	-4.31	PSI	smart domains	SM00423	42	2	9717	41	ITGB2,PLXND1
1.347e-02	-4.31	NAADP-sensitive calcium-release channel activity	molecular function	GO:0072345	5	1	18094	49	MCOLN2
1.347e-02	-4.31	neuregulin binding	molecular function	GO:0038132	5	1	18094	49	ITGAV
1.347e-02	-4.31	C-X3-C chemokine binding	molecular function	GO:0019960	5	1	18094	49	ITGAV
1.355e-02	-4.30	negative regulation of immune system process	biological process	GO:0002683	529	5	18204	49	SPI1,PTPN6,CD74,HCK,CD68
1.358e-02	-4.30	Rap1 signaling pathway	KEGG pathways	hsa04015	210	4	7161	32	TLN1,FYB1,ITGAL,ITGB2
1.358e-02	-4.30	Rap1 signaling pathway	KEGG pathways	ko04015	210	4	7161	32	ITGB2,ITGAL,FYB1,TLN1
1.359e-02	-4.30	cell development	biological process	GO:0048468	2236	12	18204	49	CD74,DNM2,DOCK2,PTPN6,RBPJ,PREX1,PLXND1,DISC1,SPI1,RBM47,SH2B3,ZFP36L1
1.361e-02	-4.30	EVL (Enah/Vasp-like)	protein interactions	51466	69	2	19454	50	FYB1,HCK
1.361e-02	-4.30	PABPC3 (poly(A) binding protein cytoplasmic 3)	protein interactions	5042	69	2	19454	50	GAB1,ARHGAP24
1.364e-02	-4.29	Signaling by ERBB2	REACTOME pathways	R-HSA-1227986	51	2	10285	36	GAB1,PTPN12
1.364e-02	-4.29	homotypic cell-cell adhesion	biological process	GO:0034109	66	2	18204	49	PTPN6,TLN1
1.364e-02	-4.29	peptidyl-tyrosine phosphorylation	biological process	GO:0018108	66	2	18204	49	HCK,PTPN6
1.369e-02	-4.29	EHD_N	pfam domains	PF16880	5	1	17795	49	EHD4
1.369e-02	-4.29	Cu-oxidase_3	pfam domains	PF07732	5	1	17795	49	HEPHL1
1.369e-02	-4.29	Lamp	pfam domains	PF01299	5	1	17795	49	CD68
1.369e-02	-4.29	DOCK_N	pfam domains	PF16172	5	1	17795	49	DOCK2
1.372e-02	-4.29	PE/DAG-bd	interpro domains	IPR002219	66	2	18521	50	ARHGAP45,AKAP13
1.376e-02	-4.29	CD2AP (CD2 associated protein)	protein interactions	23607	195	3	19454	50	SEPTIN9,HCK,DNM2
1.380e-02	-4.28	Regulation of actin cytoskeleton	KEGG pathways	ko04810	211	4	7161	32	ITGAV,ITGB2,ITGAL,TMSB4X
1.380e-02	-4.28	Regulation of actin cytoskeleton	KEGG pathways	hsa04810	211	4	7161	32	TMSB4X,ITGAL,ITGB2,ITGAV
1.382e-02	-4.28	Regulation of RhoA activity	Pathway Interaction DB	rhoa_reg_pathway	46	3	2226	25	AKAP13,ARAP1,ARHGEF18
1.386e-02	-4.28	PSMD3 (proteasome 26S subunit, non-ATPase 3)	protein interactions	5709	362	4	19454	50	ARHGAP24,CD74,CCND2,PTPN6
1.393e-02	-4.27	Scavenging by Class H Receptors	REACTOME pathways	R-HSA-3000497	4	1	10285	36	STAB1
1.395e-02	-4.27	BLK (BLK proto-oncogene, Src family tyrosine kinase)	protein interactions	640	196	3	19454	50	GAB1,HCK,FKBP5
1.399e-02	-4.27	IL6ST (interleukin 6 cytokine family signal transducer)	protein interactions	3572	70	2	19454	50	HCK,PTPN6
1.399e-02	-4.27	KRT36 (keratin 36)	protein interactions	8689	70	2	19454	50	HCK,TMSB4X
1.404e-02	-4.27	positive regulation of response to cytokine stimulus	biological process	GO:0060760	67	2	18204	49	RBM47,CD74
1.414e-02	-4.26	RNF20 (ring finger protein 20)	protein interactions	56254	197	3	19454	50	RBPJ,DISC1,ARHGAP24
1.417e-02	-4.26	CDK1 (cyclin dependent kinase 1)	protein interactions	983	560	5	19454	50	DNM2,FKBP5,DAB2,CCND2,PTPN6
1.437e-02	-4.24	MAPK4 (mitogen-activated protein kinase 4)	protein interactions	5596	71	2	19454	50	GAB1,FKBP5
1.438e-02	-4.24	ANXA2 (annexin A2)	protein interactions	302	366	4	19454	50	DISC1,AKAP13,DOCK8,TFEB
1.444e-02	-4.24	negative regulation of leukocyte mediated immunity	biological process	GO:0002704	68	2	18204	49	SPI1,PTPN6
1.444e-02	-4.24	negative regulation of interleukin-6 production	biological process	GO:0032715	68	2	18204	49	PTPN6,ELF4
1.444e-02	-4.24	cell-cell recognition	biological process	GO:0009988	68	2	18204	49	DOCK2,DOCK8
1.444e-02	-4.24	peptidyl-tyrosine modification	biological process	GO:0018212	68	2	18204	49	PTPN6,HCK
1.448e-02	-4.23	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	46	16828	46	ITM2B,DNM2,STAB1,TFEB,PREX1,ARAP1,DOCK2,MYO1F,DISC1,AKAP13,ARHGEF18,FKBP5,CD74,DAB2,ARHGAP24,ITGAL,SPI1,ME1,TMSB4X,HEPHL1,ITGB2,RXRA,ITGAV,HCK,TLN1,SLC9A7,PTGIR,ZFP36L1,PTPN6,RBM47,ANTXR2,EHD4,RBPJ,BTG1,SH2B3,RGL1,GAB1,MCOLN2,PTPN12,CCND2,DOCK8,WDFY3,PLXND1,CD68,BMP2K,ELF4
1.451e-02	-4.23	SMAD2 (SMAD family member 2)	protein interactions	4087	367	4	19454	50	DOCK8,DAB2,RXRA,ANTXR2
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	BMP2K,DAB2
1.476e-02	-4.22	JMJD1C (jumonji domain containing 1C)	protein interactions	221037	72	2	19454	50	RBPJ,RXRA
1.491e-02	-4.21	DBN1 (drebrin 1)	protein interactions	1627	370	4	19454	50	BMP2K,DISC1,ARHGAP24,DAB2
1.492e-02	-4.21	PTDSS1 (phosphatidylserine synthase 1)	protein interactions	9791	201	3	19454	50	PTPN6,RBM47,HEPHL1
1.502e-02	-4.20	I_LWEQ	prosite domains	PS50945	4	1	12186	46	TLN1
1.502e-02	-4.20	THYMOSIN_B4	prosite domains	PS00500	4	1	12186	46	TMSB4X
1.502e-02	-4.20	FAS1	prosite domains	PS50213	4	1	12186	46	STAB1
1.502e-02	-4.20	LAMP_3	prosite domains	PS51407	4	1	12186	46	CD68
1.512e-02	-4.19	SGTB (small glutamine rich tetratricopeptide repeat co-chaperone beta)	protein interactions	54557	202	3	19454	50	WDFY3,TLN1,CD68
1.512e-02	-4.19	regulation of angiogenesis	biological process	GO:0045765	355	4	18204	49	PLXND1,STAB1,GAB1,BTG1
1.512e-02	-4.19	positive regulation of hemopoiesis	biological process	GO:1903708	193	3	18204	49	ZFP36L1,CD74,SPI1
1.512e-02	-4.19	positive regulation of leukocyte differentiation	biological process	GO:1902107	193	3	18204	49	ZFP36L1,CD74,SPI1
1.515e-02	-4.19	FSD1 (fibronectin type III and SPRY domain containing 1)	protein interactions	79187	73	2	19454	50	EHD4,DISC1
1.515e-02	-4.19	STAMBPL1 (STAM binding protein like 1)	protein interactions	57559	73	2	19454	50	RBM47,BMP2K
1.515e-02	-4.19	PANK4 (pantothenate kinase 4 (inactive))	protein interactions	55229	73	2	19454	50	ARHGAP24,PTPN6
1.518e-02	-4.19	NHLRC2 (NHL repeat containing 2)	protein interactions	374354	372	4	19454	50	AKAP13,TLN1,TFEB,MYO1F
1.521e-02	-4.19	lamellipodium	cellular component	GO:0030027	203	3	19108	49	PLXND1,DOCK8,ITGAV
1.521e-02	-4.19	endocytic vesicle membrane	cellular component	GO:0030666	203	3	19108	49	STAB1,DNM2,CD74
1.522e-02	-4.19	LYSASSOCTDMP	prints domains	PR00336	4	1	5227	20	CD68
1.522e-02	-4.19	RETINOIDXR	prints domains	PR00545	4	1	5227	20	RXRA
1.526e-02	-4.18	antigen processing and presentation of peptide antigen	biological process	GO:0048002	70	2	18204	49	DNM2,CD74
1.529e-02	-4.18	Atg12-Atg5-Atg16 complex	cellular component	GO:0034274	6	1	19108	49	WDFY3
1.529e-02	-4.18	mRNA editing complex	cellular component	GO:0045293	6	1	19108	49	RBM47
1.531e-02	-4.18	MYO6 (myosin VI)	protein interactions	4646	373	4	19454	50	SEPTIN9,BMP2K,DOCK8,DAB2
1.531e-02	-4.18	DPYSL2 (dihydropyrimidinase like 2)	protein interactions	1808	203	3	19454	50	SEPTIN9,DISC1,PREX1
1.532e-02	-4.18	Nme7 (NME/NM23 family member 7)	protein interactions	171567	6	1	19454	50	TMSB4X
1.532e-02	-4.18	CD300LF (CD300 molecule like family member f)	protein interactions	146722	6	1	19454	50	PTPN6
1.532e-02	-4.18	Ncoa2 (nuclear receptor coactivator 2)	protein interactions	17978	6	1	19454	50	RXRA
1.532e-02	-4.18	ITGAX (integrin subunit alpha X)	protein interactions	3687	6	1	19454	50	ITGB2
1.532e-02	-4.18	ZNF311 (zinc finger protein 311)	protein interactions	282890	6	1	19454	50	ARHGAP24
1.532e-02	-4.18	echA1 (enoyl-CoA hydratase EchA1)	protein interactions	886723	6	1	19454	50	PTPN6
1.552e-02	-4.17	amb2 Integrin signaling	Pathway Interaction DB	amb2_neutrophils_pathway	48	3	2226	25	ITGB2,TLN1,HCK
1.554e-02	-4.16	EEF1A1P5 (eukaryotic translation elongation factor 1 alpha 1 pseudogene 5)	protein interactions	158078	74	2	19454	50	CCND2,ARHGAP24
1.568e-02	-4.16	localization within membrane	biological process	GO:0051668	549	5	18204	49	FYB1,DOCK2,EHD4,ITGB2,ITGAL
1.572e-02	-4.15	UTRN (utrophin)	protein interactions	7402	205	3	19454	50	DISC1,MCOLN2,PTPN12
1.579e-02	-4.15	IL-6 signaling pathway	WikiPathways	WP364	43	2	5310	24	HCK,GAB1
1.594e-02	-4.14	MTX3 (metaxin 3)	protein interactions	345778	75	2	19454	50	PTGIR,CD68
1.594e-02	-4.14	AKT3 (AKT serine/threonine kinase 3)	protein interactions	10000	75	2	19454	50	DAB2,FKBP5
1.594e-02	-4.14	PDAP1 (PDGFA associated protein 1)	protein interactions	11333	75	2	19454	50	DISC1,CD74
1.597e-02	-4.14	negative regulation of immune response	biological process	GO:0050777	197	3	18204	49	HCK,PTPN6,SPI1
1.599e-02	-4.14	positive regulation of cell projection organization	biological process	GO:0031346	361	4	18204	49	ARAP1,DISC1,PLXND1,SEPTIN9
1.604e-02	-4.13	regulation of aldosterone secretion	biological process	GO:2000858	6	1	18204	49	DAB2
1.604e-02	-4.13	hair follicle maturation	biological process	GO:0048820	6	1	18204	49	RBPJ
1.604e-02	-4.13	positive regulation of prostaglandin biosynthetic process	biological process	GO:0031394	6	1	18204	49	CD74
1.604e-02	-4.13	arterial endothelial cell differentiation	biological process	GO:0060842	6	1	18204	49	RBPJ
1.604e-02	-4.13	endocardium morphogenesis	biological process	GO:0003160	6	1	18204	49	RBPJ
1.604e-02	-4.13	negative regulation of amine metabolic process	biological process	GO:0033239	6	1	18204	49	ITGB2
1.604e-02	-4.13	regulation of establishment of T cell polarity	biological process	GO:1903903	6	1	18204	49	DOCK8
1.604e-02	-4.13	membrane raft distribution	biological process	GO:0031580	6	1	18204	49	DOCK2
1.604e-02	-4.13	positive regulation of chemokine (C-C motif) ligand 5 production	biological process	GO:0071651	6	1	18204	49	MCOLN2
1.604e-02	-4.13	positive regulation of vitamin D receptor signaling pathway	biological process	GO:0070564	6	1	18204	49	RXRA
1.604e-02	-4.13	regulation of macrophage inflammatory protein 1 alpha production	biological process	GO:0071640	6	1	18204	49	MCOLN2
1.604e-02	-4.13	regulation of mineralocorticoid secretion	biological process	GO:2000855	6	1	18204	49	DAB2
1.604e-02	-4.13	regulation of defense response to fungus	biological process	GO:1900150	6	1	18204	49	SPI1
1.604e-02	-4.13	radial glia-guided pyramidal neuron migration	biological process	GO:0140650	6	1	18204	49	DISC1
1.604e-02	-4.13	negative regulation of protein localization to chromatin	biological process	GO:0120186	6	1	18204	49	SPI1
1.604e-02	-4.13	apolipoprotein A-I-mediated signaling pathway	biological process	GO:0038027	6	1	18204	49	ITGAV
1.604e-02	-4.13	oncogene-induced cell senescence	biological process	GO:0090402	6	1	18204	49	SPI1
1.609e-02	-4.13	Dynamin_stalk	interpro domains	IPR000375	6	1	18521	50	DNM2
1.609e-02	-4.13	BTG-like_sf	interpro domains	IPR036054	6	1	18521	50	BTG1
1.609e-02	-4.13	Dynamin_GTPase_CS	interpro domains	IPR019762	6	1	18521	50	DNM2
1.609e-02	-4.13	DOCK_C/D_N	interpro domains	IPR021816	6	1	18521	50	DOCK8
1.609e-02	-4.13	Integrin_bsu_cyt_dom	interpro domains	IPR014836	6	1	18521	50	ITGB2
1.609e-02	-4.13	GED_dom	interpro domains	IPR020850	6	1	18521	50	DNM2
1.609e-02	-4.13	Anti_prolifrtn	interpro domains	IPR002087	6	1	18521	50	BTG1
1.609e-02	-4.13	GED	interpro domains	IPR003130	6	1	18521	50	DNM2
1.609e-02	-4.13	negative regulation of protein binding	biological process	GO:0032091	72	2	18204	49	DISC1,DAB2
1.609e-02	-4.13	positive regulation of chemokine production	biological process	GO:0032722	72	2	18204	49	CD74,MCOLN2
1.613e-02	-4.13	positive regulation of leukocyte activation	biological process	GO:0002696	362	4	18204	49	PTPN6,SPI1,CD74,DOCK8
1.614e-02	-4.13	oxidoreductase activity, acting on metal ions, oxygen as acceptor	molecular function	GO:0016724	6	1	18094	49	HEPHL1
1.614e-02	-4.13	ferroxidase activity	molecular function	GO:0004322	6	1	18094	49	HEPHL1
1.614e-02	-4.13	extracellular matrix protein binding	molecular function	GO:1990430	6	1	18094	49	ITGAV
1.614e-02	-4.13	retinoic acid-responsive element binding	molecular function	GO:0044323	6	1	18094	49	RXRA
1.614e-02	-4.13	LIM domain binding	molecular function	GO:0030274	6	1	18094	49	TLN1
1.614e-02	-4.13	type 1 angiotensin receptor binding	molecular function	GO:0031702	6	1	18094	49	ARAP1
1.614e-02	-4.13	NFAT protein binding	molecular function	GO:0051525	6	1	18094	49	SPI1
1.622e-02	-4.12	molecular transducer activity	molecular function	GO:0060089	1474	9	18094	49	PTGIR,CD74,ITGAV,PLXND1,ITGAL,PTPN6,RXRA,ITGB2,ANTXR2
1.622e-02	-4.12	signaling receptor activity	molecular function	GO:0038023	1474	9	18094	49	PLXND1,ITGAV,CD74,PTGIR,ANTXR2,ITGB2,RXRA,ITGAL,PTPN6
1.623e-02	-4.12	positive regulation of cell population proliferation	biological process	GO:0008284	992	7	18204	49	HCK,DISC1,CD74,CCND2,ITGAV,PTPN6,RBPJ
1.635e-02	-4.11	PGM3 (phosphoglucomutase 3)	protein interactions	5238	76	2	19454	50	ARHGAP24,DISC1
1.641e-02	-4.11	Integrin_b_cyt	pfam domains	PF08725	6	1	17795	49	ITGB2
1.641e-02	-4.11	GED	pfam domains	PF02212	6	1	17795	49	DNM2
1.641e-02	-4.11	BTG	pfam domains	PF07742	6	1	17795	49	BTG1
1.641e-02	-4.11	Integrin_B_tail	pfam domains	PF07965	6	1	17795	49	ITGB2
1.641e-02	-4.11	Dynamin_M	pfam domains	PF01031	6	1	17795	49	DNM2
1.641e-02	-4.11	PH_BEACH	pfam domains	PF14844	6	1	17795	49	WDFY3
1.641e-02	-4.11	DOCK_C-D_N	pfam domains	PF11878	6	1	17795	49	DOCK8
1.643e-02	-4.11	regulation of vasculature development	biological process	GO:1901342	364	4	18204	49	STAB1,BTG1,GAB1,PLXND1
1.647e-02	-4.11	protein-macromolecule adaptor activity	molecular function	GO:0030674	989	7	18094	49	AKAP13,RBM47,FKBP5,SH2B3,BTG1,DAB2,GAB1
1.648e-02	-4.11	-	gene3d domains	1.10.268.20	5	1	14470	48	EHD4
1.648e-02	-4.11	Dedicator of cytokinesis N-terminal subdomain	gene3d domains	1.20.1270.350	5	1	14470	48	DOCK2
1.652e-02	-4.10	regulation of ERBB signaling pathway	biological process	GO:1901184	73	2	18204	49	PTPN12,RBPJ
1.652e-02	-4.10	vasculogenesis	biological process	GO:0001570	73	2	18204	49	ITGAV,ZFP36L1
1.652e-02	-4.10	receptor internalization	biological process	GO:0031623	73	2	18204	49	DNM2,ITGB2
1.652e-02	-4.10	regulation of myoblast differentiation	biological process	GO:0045661	73	2	18204	49	BTG1,ZFP36L1
1.652e-02	-4.10	endothelial cell migration	biological process	GO:0043542	73	2	18204	49	PLXND1,GAB1
1.668e-02	-4.09	clathrin-coated pit	cellular component	GO:0005905	77	2	19108	49	DAB2,DNM2
1.676e-02	-4.09	TNS3 (tensin 3)	protein interactions	64759	77	2	19454	50	GAB1,PTPN12
1.676e-02	-4.09	SNX18 (sorting nexin 18)	protein interactions	112574	77	2	19454	50	DNM2,DISC1
1.677e-02	-4.09	ILWEQ	smart domains	SM00307	4	1	9717	41	TLN1
1.677e-02	-4.09	THY	smart domains	SM00152	4	1	9717	41	TMSB4X
1.677e-02	-4.09	FAS1	smart domains	SM00554	4	1	9717	41	STAB1
1.684e-02	-4.08	leukocyte activation involved in immune response	biological process	GO:0002366	201	3	18204	49	ITGAL,DOCK2,CD74
1.695e-02	-4.08	chaperone-mediated protein folding	biological process	GO:0061077	74	2	18204	49	FKBP5,CD74
1.695e-02	-4.08	Factors involved in megakaryocyte development and platelet production	REACTOME pathways	R-HSA-983231	156	3	10285	36	DOCK8,DOCK2,SH2B3
1.697e-02	-4.08	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	14	16828	46	PREX1,STAB1,MCOLN2,TFEB,GAB1,RGL1,ME1,ARHGAP24,ELF4,ARHGEF18,AKAP13,DOCK2,MYO1F,WDFY3
1.705e-02	-4.07	Tyr_Pase_AS	interpro domains	IPR016130	74	2	18521	50	PTPN12,PTPN6
1.706e-02	-4.07	regulation of protein polymerization	biological process	GO:0032271	202	3	18204	49	HCK,TMSB4X,PREX1
1.709e-02	-4.07	human chr12q24.12	chromosome location	human chr12q24.12	9	1	26134	50	SH2B3
1.720e-02	-4.06	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	24	16828	46	ELF4,DAB2,FKBP5,ARHGEF18,AKAP13,RBM47,PLXND1,ARAP1,MYO1F,ZFP36L1,WDFY3,DOCK2,DOCK8,PREX1,SLC9A7,TLN1,ITGAV,HCK,PTPN12,STAB1,RXRA,DNM2,ITM2B,ITGAL
1.728e-02	-4.06	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	24	16828	46	PLXND1,DOCK8,WDFY3,ELF4,ITGAL,PTPN12,RBM47,ARAP1,MYO1F,ZFP36L1,DOCK2,DAB2,AKAP13,ARHGEF18,FKBP5,DNM2,RXRA,ITM2B,TLN1,SLC9A7,PREX1,ITGAV,HCK,STAB1
1.732e-02	-4.06	positive regulation of metabolic process	biological process	GO:0009893	3796	17	18204	49	RBPJ,RXRA,CCND2,CD74,MCOLN2,DNM2,SPI1,RBM47,DAB2,ZFP36L1,TFEB,EHD4,ELF4,ITGB2,TMSB4X,DISC1,ARAP1
1.738e-02	-4.05	MET activates PTPN11	REACTOME pathways	R-HSA-8865999	5	1	10285	36	GAB1
1.738e-02	-4.05	NOSTRIN mediated eNOS trafficking	REACTOME pathways	R-HSA-203641	5	1	10285	36	DNM2
1.739e-02	-4.05	DCAF6 (DDB1 and CUL4 associated factor 6)	protein interactions	55827	213	3	19454	50	DOCK8,WDFY3,DAB2
1.740e-02	-4.05	defense response to other organism	biological process	GO:0098542	1006	7	18204	49	MCOLN2,CD74,HCK,PTPN6,RBPJ,STAB1,TFEB
1.742e-02	-4.05	positive regulation of response to external stimulus	biological process	GO:0032103	564	5	18204	49	TMSB4X,HCK,CD74,SPI1,RBM47
1.748e-02	-4.05	VWF_A	interpro domains	IPR002035	75	2	18521	50	ITGAL,ANTXR2
1.774e-02	-4.03	cell activation involved in immune response	biological process	GO:0002263	205	3	18204	49	ITGAL,CD74,DOCK2
1.782e-02	-4.03	regulation of axon extension	biological process	GO:0030516	76	2	18204	49	DISC1,DNM2
1.786e-02	-4.03	LAIR1 (leukocyte associated immunoglobulin like receptor 1)	protein interactions	3903	7	1	19454	50	PTPN6
1.786e-02	-4.03	NSUN7 (NOP2/Sun RNA methyltransferase family member 7)	protein interactions	79730	7	1	19454	50	PTPN6
1.786e-02	-4.03	ZCCHC24 (zinc finger CCHC-type containing 24)	protein interactions	219654	7	1	19454	50	RBM47
1.786e-02	-4.03	ZNF501 (zinc finger protein 501)	protein interactions	115560	7	1	19454	50	ARHGAP24
1.786e-02	-4.03	ZNF701 (zinc finger protein 701)	protein interactions	55762	7	1	19454	50	ARHGAP24
1.786e-02	-4.03	MYT1L (myelin transcription factor 1 like)	protein interactions	23040	7	1	19454	50	DISC1
1.786e-02	-4.03	Gadd45b (growth arrest and DNA-damage-inducible 45 beta)	protein interactions	17873	7	1	19454	50	RXRA
1.786e-02	-4.03	XKR8 (XK related 8)	protein interactions	55113	7	1	19454	50	PTGIR
1.786e-02	-4.03	SIGLEC9 (sialic acid binding Ig like lectin 9)	protein interactions	27180	7	1	19454	50	PTPN6
1.804e-02	-4.01	MAGED2 (MAGE family member D2)	protein interactions	10916	216	3	19454	50	FKBP5,PTPN6,DOCK8
1.809e-02	-4.01	BAG2 (BAG cochaperone 2)	protein interactions	9532	596	5	19454	50	DISC1,TLN1,TFEB,EHD4,HCK
1.809e-02	-4.01	AKT1 (AKT serine/threonine kinase 1)	protein interactions	207	596	5	19454	50	ZFP36L1,GAB1,PREX1,CCND2,FKBP5
1.818e-02	-4.01	kinase binding	molecular function	GO:0019900	780	6	18094	49	PTPN6,ITGB2,BTG1,CCND2,ITGAV,SH2B3
1.820e-02	-4.01	RPS27A (ribosomal protein S27a)	protein interactions	6233	393	4	19454	50	DOCK8,RBM47,GAB1,ARHGAP24
1.826e-02	-4.00	PLS3 (plastin 3)	protein interactions	5358	217	3	19454	50	TLN1,ARHGAP24,SEPTIN9
1.827e-02	-4.00	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	49	DISC1,PLXND1
1.827e-02	-4.00	positive regulation of small GTPase mediated signal transduction	biological process	GO:0051057	77	2	18204	49	AKAP13,ITGAV
1.836e-02	-4.00	plasma membrane protein complex	cellular component	GO:0098797	600	5	19108	49	CD74,ITGB2,PTPN6,ITGAV,ITGAL
1.840e-02	-4.00	regulation of leukocyte activation	biological process	GO:0002694	572	5	18204	49	DOCK8,ZFP36L1,CD74,SPI1,PTPN6
1.849e-02	-3.99	external side of plasma membrane	cellular component	GO:0009897	396	4	19108	49	ITGAV,CD74,ITGB2,ITGAL
1.866e-02	-3.98	MAPK3 (mitogen-activated protein kinase 3)	protein interactions	5595	396	4	19454	50	RXRA,GAB1,ITGAV,FKBP5
1.869e-02	-3.98	cellular response to interleukin-3	biological process	GO:0036016	7	1	18204	49	SH2B3
1.869e-02	-3.98	negative regulation of ruffle assembly	biological process	GO:1900028	7	1	18204	49	ARHGAP24
1.869e-02	-3.98	positive regulation of corticosteroid hormone secretion	biological process	GO:2000848	7	1	18204	49	DAB2
1.869e-02	-3.98	regulation of thyroid hormone mediated signaling pathway	biological process	GO:0002155	7	1	18204	49	RXRA
1.869e-02	-3.98	membrane raft localization	biological process	GO:0051665	7	1	18204	49	DOCK2
1.869e-02	-3.98	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	biological process	GO:0031086	7	1	18204	49	ZFP36L1
1.869e-02	-3.98	macropinocytosis	biological process	GO:0044351	7	1	18204	49	DOCK2
1.869e-02	-3.98	regulation of entry of bacterium into host cell	biological process	GO:2000535	7	1	18204	49	ITGAV
1.869e-02	-3.98	TRAIL-activated apoptotic signaling pathway	biological process	GO:0036462	7	1	18204	49	SPI1
1.869e-02	-3.98	response to interleukin-3	biological process	GO:0036015	7	1	18204	49	SH2B3
1.869e-02	-3.98	delamination	biological process	GO:0060232	7	1	18204	49	SPI1
1.869e-02	-3.98	chorio-allantoic fusion	biological process	GO:0060710	7	1	18204	49	ZFP36L1
1.869e-02	-3.98	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	49	RBPJ
1.869e-02	-3.98	regulation of isomerase activity	biological process	GO:0010911	7	1	18204	49	ITGB2
1.869e-02	-3.98	positive regulation of isomerase activity	biological process	GO:0010912	7	1	18204	49	ITGB2
1.869e-02	-3.98	positive regulation of dendritic cell antigen processing and presentation	biological process	GO:0002606	7	1	18204	49	CD74
1.872e-02	-3.98	negative regulation of tumor necrosis factor production	biological process	GO:0032720	78	2	18204	49	PTPN6,ELF4
1.874e-02	-3.98	MULTICOPPER_OXIDASE1	prosite domains	PS00079	5	1	12186	46	HEPHL1
1.875e-02	-3.98	Integrin_bsu_tail	interpro domains	IPR012896	7	1	18521	50	ITGB2
1.875e-02	-3.98	Dynamin	interpro domains	IPR022812	7	1	18521	50	DNM2
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	TLN1
1.875e-02	-3.98	Integrin_bsu_tail_dom_sf	interpro domains	IPR036349	7	1	18521	50	ITGB2
1.875e-02	-3.98	MYSc_Myo1	interpro domains	IPR036072	7	1	18521	50	MYO1F
1.875e-02	-3.98	Dynamin_GTPase	interpro domains	IPR001401	7	1	18521	50	DNM2
1.881e-02	-3.97	MHC class II protein binding	molecular function	GO:0042289	7	1	18094	49	CD74
1.881e-02	-3.97	LBD domain binding	molecular function	GO:0050693	7	1	18094	49	RXRA
1.881e-02	-3.97	clathrin-coated vesicle	cellular component	GO:0030136	220	3	19108	49	CD74,DNM2,DAB2
1.883e-02	-3.97	negative regulation of cell population proliferation	biological process	GO:0008285	791	6	18204	49	RBPJ,SH2B3,PTPN6,BTG1,PTGIR,DAB2
1.886e-02	-3.97	LINC00839 (long intergenic non-protein coding RNA 839)	protein interactions	84856	82	2	19454	50	AKAP13,SEPTIN9
1.886e-02	-3.97	MEF2D (myocyte enhancer factor 2D)	protein interactions	4209	82	2	19454	50	RXRA,RBPJ
1.893e-02	-3.97	CDK5 (cyclin dependent kinase 5)	protein interactions	1020	220	3	19454	50	FKBP5,CCND2,TLN1
1.909e-02	-3.96	positive regulation of cell activation	biological process	GO:0050867	381	4	18204	49	DOCK8,PTPN6,SPI1,CD74
1.917e-02	-3.95	myeloid cell development	biological process	GO:0061515	79	2	18204	49	SH2B3,PTPN6
1.917e-02	-3.95	positive regulation of blood vessel endothelial cell migration	biological process	GO:0043536	79	2	18204	49	GAB1,TMSB4X
1.925e-02	-3.95	Signaling events mediated by Stem cell factor receptor (c-Kit)	Pathway Interaction DB	kitpathway	52	3	2226	25	PTPN6,SH2B3,GAB1
1.925e-02	-3.95	RHOB (ras homolog family member B)	protein interactions	388	832	6	19454	50	AKAP13,ANTXR2,ITGAV,GAB1,ARHGEF18,DAB2
1.930e-02	-3.95	WH_DNA-bd_sf	interpro domains	IPR036390	211	3	18521	50	PREX1,SPI1,ELF4
1.930e-02	-3.95	NEXN (nexilin F-actin binding protein)	protein interactions	91624	83	2	19454	50	ARHGAP24,DISC1
1.930e-02	-3.95	TUT4 (terminal uridylyl transferase 4)	protein interactions	23318	83	2	19454	50	FKBP5,RBM47
1.930e-02	-3.95	N4BP2 (NEDD4 binding protein 2)	protein interactions	55728	83	2	19454	50	RBM47,DISC1
1.930e-02	-3.95	WDR70 (WD repeat domain 70)	protein interactions	55100	83	2	19454	50	RBPJ,ARHGAP24
1.939e-02	-3.94	YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta)	protein interactions	10971	1076	7	19454	50	DISC1,ZFP36L1,GAB1,CD74,AKAP13,TFEB,TLN1
1.959e-02	-3.93	mouth	COSMIC cancer mutations	mouth	9004	32	16828	46	HEPHL1,TMSB4X,PLXND1,DOCK8,WDFY3,CCND2,GAB1,MCOLN2,PTPN12,ME1,BTG1,ARHGEF18,RBPJ,CD74,EHD4,AKAP13,RBM47,DISC1,PTPN6,ARAP1,DOCK2,MYO1F,ZFP36L1,PTGIR,PREX1,TLN1,ITGAV,STAB1,HCK,RXRA,DNM2,ITGB2
1.959e-02	-3.93	regulation of leukocyte cell-cell adhesion	biological process	GO:1903037	384	4	18204	49	DOCK8,ITGB2,CD74,PTPN6
1.962e-02	-3.93	TGM1 (transglutaminase 1)	protein interactions	7051	223	3	19454	50	ARHGAP24,TLN1,DOCK2
1.962e-02	-3.93	FGFR2 (fibroblast growth factor receptor 2)	protein interactions	2263	223	3	19454	50	PTPN6,DNM2,PTPN12
1.963e-02	-3.93	negative regulation of tumor necrosis factor superfamily cytokine production	biological process	GO:1903556	80	2	18204	49	ELF4,PTPN6
1.974e-02	-3.93	PPARA (peroxisome proliferator activated receptor alpha)	protein interactions	5465	84	2	19454	50	RXRA,AKAP13
1.974e-02	-3.93	NFKBIB (NFKB inhibitor beta)	protein interactions	4793	84	2	19454	50	RXRA,FKBP5
1.974e-02	-3.93	KRTAP3-1 (keratin associated protein 3-1)	protein interactions	83896	84	2	19454	50	DOCK2,HCK
1.974e-02	-3.93	NCAPG2 (non-SMC condensin II complex subunit G2)	protein interactions	54892	84	2	19454	50	FKBP5,ARHGAP24
1.974e-02	-3.92	-	gene3d domains	2.40.160.110	6	1	14470	48	CD68
1.974e-02	-3.92	I/LWEQ domain	gene3d domains	1.20.1410.10	6	1	14470	48	TLN1
1.974e-02	-3.92	Dynamin, middle domain	gene3d domains	1.20.120.1240	6	1	14470	48	DNM2
1.974e-02	-3.92	Anti-proliferative protein, N-terminal domain	gene3d domains	3.90.640.90	6	1	14470	48	BTG1
1.976e-02	-3.92	CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2)	protein interactions	830	403	4	19454	50	HEPHL1,BMP2K,DAB2,ARAP1
1.985e-02	-3.92	negative regulation of cell activation	biological process	GO:0050866	214	3	18204	49	PTPN6,SH2B3,CD74
1.991e-02	-3.92	CLTC (clathrin heavy chain)	protein interactions	1213	611	5	19454	50	BMP2K,TLN1,DAB2,EHD4,DNM2
1.996e-02	-3.91	Malaria	KEGG pathways	ko05144	49	2	7161	32	ITGAL,ITGB2
1.996e-02	-3.91	Malaria	KEGG pathways	hsa05144	49	2	7161	32	ITGB2,ITGAL
2.009e-02	-3.91	outflow tract morphogenesis	biological process	GO:0003151	81	2	18204	49	PLXND1,RBPJ
2.015e-02	-3.90	ZF_DAG_PE_1	prosite domains	PS00479	58	2	12186	46	AKAP13,ARHGAP45
2.018e-02	-3.90	CREM (cAMP responsive element modulator)	protein interactions	1390	85	2	19454	50	RBPJ,SPI1
2.018e-02	-3.90	ZAP70 (zeta chain of T cell receptor associated protein kinase 70)	protein interactions	7535	85	2	19454	50	PTPN6,SH2B3
2.019e-02	-3.90	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	16	16828	46	CCND2,TFEB,HCK,HEPHL1,DAB2,ELF4,BTG1,AKAP13,EHD4,CD74,RBM47,ANTXR2,TMSB4X,DOCK8,ZFP36L1,WDFY3
2.019e-02	-3.90	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	16	16828	46	CCND2,TFEB,HCK,HEPHL1,DAB2,ELF4,BTG1,AKAP13,EHD4,CD74,RBM47,ANTXR2,TMSB4X,DOCK8,ZFP36L1,WDFY3
2.023e-02	-3.90	IL-3 Signaling Pathway	WikiPathways	WP286	49	2	5310	24	PTPN6,HCK
2.032e-02	-3.90	PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2)	protein interactions	5296	226	3	19454	50	HCK,STAB1,GAB1
2.034e-02	-3.90	regulation of myeloid cell differentiation	biological process	GO:0045637	216	3	18204	49	SPI1,CD74,ZFP36L1
2.034e-02	-3.90	cell chemotaxis	biological process	GO:0060326	216	3	18204	49	GAB1,ITGB2,PREX1
2.038e-02	-3.89	ZNF28 (zinc finger protein 28)	protein interactions	7576	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	OSGEPL1 (O-sialoglycoprotein endopeptidase like 1)	protein interactions	64172	8	1	19454	50	MCOLN2
2.038e-02	-3.89	ZNF236 (zinc finger protein 236)	protein interactions	7776	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	Prkca (protein kinase C, alpha)	protein interactions	24680	8	1	19454	50	AKAP13
2.038e-02	-3.89	LILRB1 (leukocyte immunoglobulin like receptor B1)	protein interactions	10859	8	1	19454	50	PTPN6
2.038e-02	-3.89	KMO (kynurenine 3-monooxygenase)	protein interactions	8564	8	1	19454	50	DISC1
2.038e-02	-3.89	ZNF568 (zinc finger protein 568)	protein interactions	374900	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	TREML1 (triggering receptor expressed on myeloid cells like 1)	protein interactions	340205	8	1	19454	50	PTPN6
2.038e-02	-3.89	SLC9A7 (solute carrier family 9 member A7)	protein interactions	84679	8	1	19454	50	SLC9A7
2.038e-02	-3.89	CD1D (CD1d molecule)	protein interactions	912	8	1	19454	50	CD74
2.042e-02	-3.89	BAG3 (BAG cochaperone 3)	protein interactions	9531	615	5	19454	50	GAB1,DOCK8,FKBP5,DNM2,WDFY3
2.055e-02	-3.88	PRKCD (protein kinase C delta)	protein interactions	5580	227	3	19454	50	PTPN6,ITGB2,DAB2
2.056e-02	-3.88	granulocyte chemotaxis	biological process	GO:0071621	82	2	18204	49	ITGB2,PREX1
2.056e-02	-3.88	T cell activation involved in immune response	biological process	GO:0002286	82	2	18204	49	ITGAL,CD74
2.056e-02	-3.88	regulation of bone mineralization	biological process	GO:0030500	82	2	18204	49	BMP2K,RXRA
2.057e-02	-3.88	Natural killer cell mediated cytotoxicity	KEGG pathways	hsa04650	132	3	7161	32	PTPN6,ITGB2,ITGAL
2.057e-02	-3.88	Natural killer cell mediated cytotoxicity	KEGG pathways	ko04650	132	3	7161	32	ITGAL,ITGB2,PTPN6
2.061e-02	-3.88	regulation of immune effector process	biological process	GO:0002697	390	4	18204	49	CD74,SPI1,PTPN6,ITGB2
2.082e-02	-3.87	CD22 mediated BCR regulation	REACTOME pathways	R-HSA-5690714	6	1	10285	36	PTPN6
2.082e-02	-3.87	MET activates PI3K/AKT signaling	REACTOME pathways	R-HSA-8851907	6	1	10285	36	GAB1
2.103e-02	-3.86	PCNT (pericentrin)	protein interactions	5116	229	3	19454	50	DNM2,DISC1,SEPTIN9
2.103e-02	-3.86	PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase)	protein interactions	5110	229	3	19454	50	ARHGAP24,AKAP13,DOCK8
2.103e-02	-3.86	positive regulation of B cell activation	biological process	GO:0050871	83	2	18204	49	CD74,SPI1
2.108e-02	-3.86	MYH7 (myosin heavy chain 7)	protein interactions	4625	87	2	19454	50	RBPJ,DISC1
2.108e-02	-3.86	GK (glycerol kinase)	protein interactions	2710	87	2	19454	50	PTGIR,RXRA
2.115e-02	-3.86	supramolecular fiber organization	biological process	GO:0097435	593	5	18204	49	MYO1F,ARAP1,TMSB4X,PREX1,DNM2
2.129e-02	-3.85	PDGFR-beta signaling pathway	Pathway Interaction DB	pdgfrbpathway	54	3	2226	25	GAB1,DNM2,HCK
2.134e-02	-3.85	regulation of aldosterone biosynthetic process	biological process	GO:0032347	8	1	18204	49	DAB2
2.134e-02	-3.85	negative regulation of erythrocyte differentiation	biological process	GO:0045647	8	1	18204	49	ZFP36L1
2.134e-02	-3.85	dorsal aorta morphogenesis	biological process	GO:0035912	8	1	18204	49	RBPJ
2.134e-02	-3.85	regulation of platelet-derived growth factor receptor-beta signaling pathway	biological process	GO:2000586	8	1	18204	49	PTPN12
2.134e-02	-3.85	dichotomous subdivision of an epithelial terminal unit	biological process	GO:0060600	8	1	18204	49	PLXND1
2.134e-02	-3.85	regulation of NADP metabolic process	biological process	GO:1902031	8	1	18204	49	ME1
2.134e-02	-3.85	regulation of aldosterone metabolic process	biological process	GO:0032344	8	1	18204	49	DAB2
2.134e-02	-3.85	positive regulation of unsaturated fatty acid biosynthetic process	biological process	GO:2001280	8	1	18204	49	CD74
2.134e-02	-3.85	regulation of cellular pH reduction	biological process	GO:0032847	8	1	18204	49	SLC9A7
2.134e-02	-3.85	endothelial cell fate commitment	biological process	GO:0060839	8	1	18204	49	RBPJ
2.134e-02	-3.85	negative regulation of low-density lipoprotein receptor activity	biological process	GO:1905598	8	1	18204	49	ITGAV
2.134e-02	-3.85	positive regulation of ligase activity	biological process	GO:0051351	8	1	18204	49	TMSB4X
2.134e-02	-3.85	positive regulation of non-motile cilium assembly	biological process	GO:1902857	8	1	18204	49	SEPTIN9
2.134e-02	-3.85	regulation of keratinocyte apoptotic process	biological process	GO:1902172	8	1	18204	49	ZFP36L1
2.134e-02	-3.85	T cell extravasation	biological process	GO:0072683	8	1	18204	49	ITGAL
2.134e-02	-3.85	G protein-coupled receptor signaling pathway involved in heart process	biological process	GO:0086103	8	1	18204	49	AKAP13
2.134e-02	-3.85	Immune System	REACTOME pathways	R-HSA-168256	2101	13	10285	36	ARHGAP45,GAB1,PTPN6,ITGAL,DOCK2,CD68,TLN1,ITGAV,DNM2,ITGB2,FYB1,CD74,HCK
2.140e-02	-3.84	Integrin_beta_N	interpro domains	IPR033760	8	1	18521	50	ITGB2
2.140e-02	-3.84	Prostanoid_rcpt	interpro domains	IPR008365	8	1	18521	50	PTGIR
2.140e-02	-3.84	Integrin_bsu_VWA	interpro domains	IPR002369	8	1	18521	50	ITGB2
2.140e-02	-3.84	TIG1_plexin	interpro domains	IPR041019	8	1	18521	50	PLXND1
2.140e-02	-3.84	Myosin_TH1	interpro domains	IPR010926	8	1	18521	50	MYO1F
2.140e-02	-3.84	PH-BEACH_dom	interpro domains	IPR023362	8	1	18521	50	WDFY3
2.146e-02	-3.84	CD4 receptor binding	molecular function	GO:0042609	8	1	18094	49	CD74
2.146e-02	-3.84	malate dehydrogenase activity	molecular function	GO:0016615	8	1	18094	49	ME1
2.146e-02	-3.84	phosphorylation-dependent protein binding	molecular function	GO:0140031	8	1	18094	49	PTPN6
2.151e-02	-3.84	NBPF19 (NBPF member 19)	protein interactions	101060226	231	3	19454	50	DOCK2,ITGB2,HCK
2.153e-02	-3.84	PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta)	protein interactions	5291	88	2	19454	50	HCK,SEPTIN9
2.157e-02	-3.84	YTHDC1 (YTH N6-methyladenosine RNA binding protein C1)	protein interactions	91746	414	4	19454	50	AKAP13,FYB1,RBM47,SPI1
2.159e-02	-3.84	CSK (C-terminal Src kinase)	protein interactions	1445	854	6	19454	50	GAB1,DISC1,MCOLN2,DAB2,PTPN12,HCK
2.174e-02	-3.83	EGFR (epidermal growth factor receptor)	protein interactions	1956	3105	14	19454	50	ITGAV,GAB1,FKBP5,ARHGEF18,HCK,ITGB2,PTPN6,TLN1,PTPN12,DAB2,SH2B3,SEPTIN9,DNM2,EHD4
2.182e-02	-3.82	Myosin_TH1	pfam domains	PF06017	8	1	17795	49	MYO1F
2.182e-02	-3.82	PSI_integrin	pfam domains	PF17205	8	1	17795	49	ITGB2
2.182e-02	-3.82	Integrin_beta	pfam domains	PF00362	8	1	17795	49	ITGB2
2.182e-02	-3.82	TIG_plexin	pfam domains	PF17960	8	1	17795	49	PLXND1
2.199e-02	-3.82	SLC25A41 (solute carrier family 25 member 41)	protein interactions	284427	89	2	19454	50	DAB2,BMP2K
2.199e-02	-3.82	GPX4 (glutathione peroxidase 4)	protein interactions	2879	89	2	19454	50	PTPN12,ME1
2.212e-02	-3.81	RHOJ (ras homolog family member J)	protein interactions	57381	628	5	19454	50	EHD4,ITM2B,DOCK8,ITGAV,GAB1
2.224e-02	-3.81	EIF3L (eukaryotic translation initiation factor 3 subunit L)	protein interactions	51386	234	3	19454	50	ARHGAP24,CD74,DNM2
2.224e-02	-3.81	JAK1 (Janus kinase 1)	protein interactions	3716	234	3	19454	50	GAB1,DISC1,PTPN6
2.241e-02	-3.80	large_intestine-colon	COSMIC cancer mutations	large_intestine-colon	1291	8	16828	46	ARHGAP24,PREX1,TLN1,PTPN6,HEPHL1,DOCK2,STAB1,ITGAL
2.244e-02	-3.80	BTG_2	prosite domains	PS01203	6	1	12186	46	BTG1
2.244e-02	-3.80	G_DYNAMIN_1	prosite domains	PS00410	6	1	12186	46	DNM2
2.244e-02	-3.80	GED	prosite domains	PS51388	6	1	12186	46	DNM2
2.244e-02	-3.80	BTG_1	prosite domains	PS00960	6	1	12186	46	BTG1
2.247e-02	-3.80	positive regulation of lipid transport	biological process	GO:0032370	86	2	18204	49	DAB2,RXRA
2.251e-02	-3.79	trunk	COSMIC cancer mutations	trunk	3554	16	16828	46	ITGB2,ITGAL,TLN1,PTPN12,TFEB,HCK,STAB1,RBM47,DISC1,DOCK8,MYO1F,DOCK2,WDFY3,HEPHL1,DAB2,FKBP5
2.255e-02	-3.79	regulation of growth	biological process	GO:0040008	603	5	18204	49	RBPJ,BTG1,DISC1,DNM2,DAB2
2.255e-02	-3.79	regulation of cell growth	biological process	GO:0001558	401	4	18204	49	DISC1,DNM2,DAB2,BTG1
2.260e-02	-3.79	Tyr_Pase_dom	interpro domains	IPR000387	86	2	18521	50	PTPN12,PTPN6
2.272e-02	-3.78	human chr4q21.23	chromosome location	human chr4q21.23	12	1	26134	50	WDFY3
2.274e-02	-3.78	CTSL (cathepsin L)	protein interactions	1514	236	3	19454	50	RXRA,CD74,ITM2B
2.275e-02	-3.78	ANTIPRLFBTG1	prints domains	PR00310	6	1	5227	20	BTG1
2.285e-02	-3.78	unconventional myosin complex	cellular component	GO:0016461	9	1	19108	49	MYO1F
2.290e-02	-3.78	NIM1K (NIM1 serine/threonine protein kinase)	protein interactions	167359	9	1	19454	50	SEPTIN9
2.290e-02	-3.78	SEMA3A (semaphorin 3A)	protein interactions	10371	9	1	19454	50	DISC1
2.290e-02	-3.78	ZNF766 (zinc finger protein 766)	protein interactions	90321	9	1	19454	50	ARHGAP24
2.290e-02	-3.78	KLRA1P (killer cell lectin like receptor A1, pseudogene)	protein interactions	10748	9	1	19454	50	PTPN6
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	ARHGAP24
2.290e-02	-3.78	CLEC4F (C-type lectin domain family 4 member F)	protein interactions	165530	9	1	19454	50	ITGAV
2.290e-02	-3.78	PPFIA4 (PTPRF interacting protein alpha 4)	protein interactions	8497	9	1	19454	50	DISC1
2.290e-02	-3.78	PCNX4 (pecanex 4)	protein interactions	64430	9	1	19454	50	DISC1
2.290e-02	-3.78	HLA-DMA (major histocompatibility complex, class II, DM alpha)	protein interactions	3108	9	1	19454	50	CD74
2.290e-02	-3.78	RBM46 (RNA binding motif protein 46)	protein interactions	166863	9	1	19454	50	RBM47
2.290e-02	-3.78	LILRB2 (leukocyte immunoglobulin like receptor B2)	protein interactions	10288	9	1	19454	50	PTPN6
2.292e-02	-3.78	TMEM179B (transmembrane protein 179B)	protein interactions	374395	91	2	19454	50	PTGIR,CD68
2.292e-02	-3.78	TRMT6 (tRNA methyltransferase 6 non-catalytic subunit)	protein interactions	51605	91	2	19454	50	FKBP5,SEPTIN9
2.292e-02	-3.78	TRIO (trio Rho guanine nucleotide exchange factor)	protein interactions	7204	91	2	19454	50	DISC1,DAB2
2.292e-02	-3.78	AMIGO1 (adhesion molecule with Ig like domain 1)	protein interactions	57463	91	2	19454	50	DNM2,ITM2B
2.308e-02	-3.77	LAMP1 (lysosomal associated membrane protein 1)	protein interactions	3916	635	5	19454	50	ARHGAP24,DISC1,ITGAV,ITM2B,EHD4
2.320e-02	-3.76	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	4	PTGIR
2.320e-02	-3.76	Transfer of Acetyl Groups into Mitochondria	SMPDB pathways	SMP0000466	8	1	1369	4	ME1
2.324e-02	-3.76	MBNL1 (muscleblind like splicing regulator 1)	protein interactions	4154	238	3	19454	50	DNM2,RBM47,HEPHL1
2.335e-02	-3.76	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	40	16828	46	ITM2B,ITGB2,RXRA,DNM2,TFEB,STAB1,ITGAV,PREX1,PTGIR,TLN1,SLC9A7,MYO1F,DOCK2,ZFP36L1,ARAP1,ANTXR2,RBM47,PTPN6,DISC1,ARHGEF18,FKBP5,EHD4,AKAP13,ARHGAP24,DAB2,SPI1,ITGAL,SH2B3,RGL1,ME1,MCOLN2,PTPN12,GAB1,CCND2,WDFY3,DOCK8,PLXND1,BMP2K,ELF4,HEPHL1
2.339e-02	-3.76	KDM5B (lysine demethylase 5B)	protein interactions	10765	92	2	19454	50	BMP2K,ELF4
2.341e-02	-3.75	immune response-activating cell surface receptor signaling pathway	biological process	GO:0002429	228	3	18204	49	PTPN6,FYB1,HCK
2.348e-02	-3.75	RANBP9 (RAN binding protein 9)	protein interactions	10048	425	4	19454	50	DISC1,ITGAL,ARHGAP24,ITGB2
2.348e-02	-3.75	Semaphorin interactions	REACTOME pathways	R-HSA-373755	68	2	10285	36	PLXND1,TLN1
2.350e-02	-3.75	TBP (TATA-box binding protein)	protein interactions	6908	239	3	19454	50	SPI1,RBPJ,RXRA
2.353e-02	-3.75	ZF_DAG_PE_2	prosite domains	PS50081	63	2	12186	46	ARHGAP45,AKAP13
2.368e-02	-3.74	regulation of plasma membrane bounded cell projection assembly	biological process	GO:0120032	229	3	18204	49	SEPTIN9,ARHGAP24,ARAP1
2.370e-02	-3.74	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	27	16828	46	MYO1F,DOCK2,ZFP36L1,ANTXR2,FKBP5,AKAP13,EHD4,BTG1,ITM2B,RXRA,DNM2,STAB1,PTGIR,PREX1,SLC9A7,TLN1,WDFY3,PLXND1,ELF4,HEPHL1,ITGAL,RGL1,SH2B3,ME1,PTPN12,MCOLN2,GAB1
2.387e-02	-3.74	LRRC8E (leucine rich repeat containing 8 VRAC subunit E)	protein interactions	80131	93	2	19454	50	PTGIR,ARHGAP24
2.387e-02	-3.74	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	50	CCND2,CD74
2.387e-02	-3.74	UTP25 (UTP25 small subunit processome component)	protein interactions	27042	93	2	19454	50	BMP2K,PREX1
2.395e-02	-3.73	positive regulation of lipid biosynthetic process	biological process	GO:0046889	89	2	18204	49	DAB2,CD74
2.395e-02	-3.73	regulation of leukocyte apoptotic process	biological process	GO:2000106	89	2	18204	49	CD74,DOCK8
2.397e-02	-3.73	antibacterial innate immune response	biological process	GO:0140367	9	1	18204	49	TFEB
2.397e-02	-3.73	regulation of mRNA 3'-end processing	biological process	GO:0031440	9	1	18204	49	ZFP36L1
2.397e-02	-3.73	respiratory burst involved in defense response	biological process	GO:0002679	9	1	18204	49	HCK
2.397e-02	-3.73	peroxisome proliferator activated receptor signaling pathway	biological process	GO:0035357	9	1	18204	49	RXRA
2.397e-02	-3.73	positive regulation of antigen processing and presentation	biological process	GO:0002579	9	1	18204	49	CD74
2.397e-02	-3.73	establishment of T cell polarity	biological process	GO:0001768	9	1	18204	49	DOCK2
2.397e-02	-3.73	negative regulation of inflammatory response to wounding	biological process	GO:0106015	9	1	18204	49	PTPN6
2.397e-02	-3.73	regulation of ligase activity	biological process	GO:0051340	9	1	18204	49	TMSB4X
2.397e-02	-3.73	mesendoderm development	biological process	GO:0048382	9	1	18204	49	ZFP36L1
2.397e-02	-3.73	positive regulation of hormone biosynthetic process	biological process	GO:0046886	9	1	18204	49	DAB2
2.397e-02	-3.73	negative regulation of chemokine-mediated signaling pathway	biological process	GO:0070100	9	1	18204	49	SH2B3
2.397e-02	-3.73	regulation of protein localization to chromatin	biological process	GO:1905634	9	1	18204	49	SPI1
2.397e-02	-3.73	malate metabolic process	biological process	GO:0006108	9	1	18204	49	ME1
2.397e-02	-3.73	positive regulation of early endosome to late endosome transport	biological process	GO:2000643	9	1	18204	49	DAB2
2.397e-02	-3.73	regulation of sarcomere organization	biological process	GO:0060297	9	1	18204	49	AKAP13
2.397e-02	-3.73	negative regulation of antigen processing and presentation	biological process	GO:0002578	9	1	18204	49	CD68
2.397e-02	-3.73	positive regulation of Wnt signaling pathway, planar cell polarity pathway	biological process	GO:2000096	9	1	18204	49	DAB2
2.404e-02	-3.73	BRICHOS_dom	interpro domains	IPR007084	9	1	18521	50	ITM2B
2.404e-02	-3.73	BEACH_dom_sf	interpro domains	IPR036372	9	1	18521	50	WDFY3
2.404e-02	-3.73	Aminoacid_DH-like_N_sf	interpro domains	IPR046346	9	1	18521	50	ME1
2.404e-02	-3.73	BEACH_dom	interpro domains	IPR000409	9	1	18521	50	WDFY3
2.404e-02	-3.73	Integrin_bsu	interpro domains	IPR015812	9	1	18521	50	ITGB2
2.404e-02	-3.73	Plexin_RBD	interpro domains	IPR046800	9	1	18521	50	PLXND1
2.404e-02	-3.73	NaH_exchanger	interpro domains	IPR004709	9	1	18521	50	SLC9A7
2.404e-02	-3.73	Plexin_cytoplasmic_RasGAP_dom	interpro domains	IPR013548	9	1	18521	50	PLXND1
2.412e-02	-3.72	angiotensin receptor binding	molecular function	GO:0031701	9	1	18094	49	ARAP1
2.422e-02	-3.72	regulation of cell projection assembly	biological process	GO:0060491	231	3	18204	49	ARHGAP24,ARAP1,SEPTIN9
2.425e-02	-3.72	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	REACTOME pathways	R-HSA-210744	7	1	10285	36	RBPJ
2.435e-02	-3.72	KANSL1 (KAT8 regulatory NSL complex subunit 1)	protein interactions	284058	94	2	19454	50	ELF4,DISC1
2.436e-02	-3.71	regulation of cell development	biological process	GO:0060284	839	6	18204	49	PTPN6,SPI1,CD74,ZFP36L1,DISC1,PLXND1
2.446e-02	-3.71	regulation of Rho protein signal transduction	biological process	GO:0035023	90	2	18204	49	ARHGEF18,AKAP13
2.446e-02	-3.71	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	49	TMSB4X,ME1
2.452e-02	-3.71	Plexin_cytopl	pfam domains	PF08337	9	1	17795	49	PLXND1
2.452e-02	-3.71	Beach	pfam domains	PF02138	9	1	17795	49	WDFY3
2.452e-02	-3.71	BRICHOS	pfam domains	PF04089	9	1	17795	49	ITM2B
2.452e-02	-3.71	Plexin_RBD	pfam domains	PF20170	9	1	17795	49	PLXND1
2.470e-02	-3.70	WH-like_DNA-bd_sf	interpro domains	IPR036388	232	3	18521	50	ELF4,PREX1,SPI1
2.475e-02	-3.70	KRT40 (keratin 40)	protein interactions	125115	432	4	19454	50	HCK,DOCK2,DOCK8,TMSB4X
2.480e-02	-3.70	Staphylococcus aureus infection	KEGG pathways	hsa05150	55	2	7161	32	ITGAL,ITGB2
2.480e-02	-3.70	Staphylococcus aureus infection	KEGG pathways	ko05150	55	2	7161	32	ITGAL,ITGB2
2.483e-02	-3.70	PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1)	protein interactions	9051	95	2	19454	50	DNM2,PTPN12
2.487e-02	-3.69	regulation of defense response	biological process	GO:0031347	843	6	18204	49	ELF4,HCK,TMSB4X,SPI1,PTPN6,RBM47
2.495e-02	-3.69	axon	cellular component	GO:0030424	650	5	19108	49	WDFY3,PREX1,PLXND1,DNM2,DISC1
2.496e-02	-3.69	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	49	TMSB4X,ME1
2.505e-02	-3.69	PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase)	protein interactions	10606	245	3	19454	50	PTPN12,FKBP5,DOCK8
2.506e-02	-3.69	GED	smart domains	SM00302	6	1	9717	41	DNM2
2.506e-02	-3.69	Integrin_b_cyt	smart domains	SM01241	6	1	9717	41	ITGB2
2.506e-02	-3.69	btg1	smart domains	SM00099	6	1	9717	41	BTG1
2.529e-02	-3.68	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	19	19454	50	PTPN12,DISC1,AKAP13,DNM2,ARAP1,EHD4,PREX1,SEPTIN9,FKBP5,RBPJ,ARHGEF18,BMP2K,ANTXR2,ITGAV,ME1,WDFY3,CCND2,TLN1,TMSB4X
2.534e-02	-3.68	Cell adhesion molecules (CAMs)	KEGG pathways	ko04514	143	3	7161	32	ITGB2,ITGAV,ITGAL
2.534e-02	-3.68	Cell adhesion molecules (CAMs)	KEGG pathways	hsa04514	143	3	7161	32	ITGAL,ITGB2,ITGAV
2.537e-02	-3.67	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	10	19454	50	DAB2,FKBP5,SLC9A7,ARHGEF18,RBM47,ARHGAP24,AKAP13,ARAP1,SEPTIN9,RXRA
2.541e-02	-3.67	ANGPTL3 (angiopoietin like 3)	protein interactions	27329	10	1	19454	50	ITGAV
2.541e-02	-3.67	CDKL4 (cyclin dependent kinase like 4)	protein interactions	344387	10	1	19454	50	FKBP5
2.541e-02	-3.67	OR51E2 (olfactory receptor family 51 subfamily E member 2)	protein interactions	81285	10	1	19454	50	HEPHL1
2.541e-02	-3.67	SIGLEC10 (sialic acid binding Ig like lectin 10)	protein interactions	89790	10	1	19454	50	PTPN6
2.541e-02	-3.67	PRTG (protogenin)	protein interactions	283659	10	1	19454	50	DISC1
2.541e-02	-3.67	PGA4 (pepsinogen A4)	protein interactions	643847	10	1	19454	50	CD74
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	ITGB2
2.541e-02	-3.67	SIGLEC7 (sialic acid binding Ig like lectin 7)	protein interactions	27036	10	1	19454	50	PTPN6
2.541e-02	-3.67	ZNF852 (zinc finger protein 852)	protein interactions	285346	10	1	19454	50	ARHGAP24
2.541e-02	-3.67	HEPN1 (hepatocellular carcinoma, down-regulated 1)	protein interactions	641654	10	1	19454	50	HEPHL1
2.541e-02	-3.67	METTL26 (methyltransferase like 26)	protein interactions	84326	10	1	19454	50	DISC1
2.541e-02	-3.67	DMTF1 (cyclin D binding myb like transcription factor 1)	protein interactions	9988	10	1	19454	50	CCND2
2.541e-02	-3.67	FCER2 (Fc epsilon receptor II)	protein interactions	2208	10	1	19454	50	ITGB2
2.541e-02	-3.67	NRAP (nebulin related anchoring protein)	protein interactions	4892	10	1	19454	50	TLN1
2.541e-02	-3.67	CDH4 (cadherin 4)	protein interactions	1002	10	1	19454	50	RBPJ
2.541e-02	-3.67	ZNF589 (zinc finger protein 589)	protein interactions	51385	10	1	19454	50	RBPJ
2.541e-02	-3.67	ZNF606 (zinc finger protein 606)	protein interactions	80095	10	1	19454	50	ARHGAP24
2.541e-02	-3.67	KCNN3 (potassium calcium-activated channel subfamily N member 3)	protein interactions	3782	10	1	19454	50	DNM2
2.541e-02	-3.67	SPAG11A (sperm associated antigen 11A)	protein interactions	653423	10	1	19454	50	ITGAV
2.547e-02	-3.67	ATG16L1 (autophagy related 16 like 1)	protein interactions	55054	1138	7	19454	50	TFEB,DOCK2,AKAP13,TLN1,WDFY3,DNM2,ARHGAP45
2.548e-02	-3.67	positive regulation of transporter activity	biological process	GO:0032411	92	2	18204	49	TMSB4X,RXRA
2.548e-02	-3.67	response to chemokine	biological process	GO:1990868	92	2	18204	49	SH2B3,DOCK8
2.548e-02	-3.67	cellular response to chemokine	biological process	GO:1990869	92	2	18204	49	DOCK8,SH2B3
2.573e-02	-3.66	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	16	16828	46	HEPHL1,BTG1,AKAP13,CD74,PLXND1,ZFP36L1,DOCK2,WDFY3,CCND2,PTPN12,HCK,MCOLN2,GAB1,ITGAV,ME1,ITM2B
2.581e-02	-3.66	CPNE2 (copine 2)	protein interactions	221184	97	2	19454	50	SEPTIN9,RBM47
2.581e-02	-3.66	Tpm1 (tropomyosin 1, alpha)	protein interactions	22003	97	2	19454	50	DAB2,BMP2K
2.585e-02	-3.66	SYK (spleen associated tyrosine kinase)	protein interactions	6850	248	3	19454	50	PTPN6,ITGB2,GAB1
2.599e-02	-3.65	regulation of stress fiber assembly	biological process	GO:0051492	93	2	18204	49	ARHGEF18,ARAP1
2.599e-02	-3.65	regulation of extent of cell growth	biological process	GO:0061387	93	2	18204	49	DNM2,DISC1
2.605e-02	-3.65	GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1)	protein interactions	8729	439	4	19454	50	SEPTIN9,DAB2,PTPN6,TLN1
2.625e-02	-3.64	cell surface	cellular component	GO:0009986	896	6	19108	49	ITGAL,ANTXR2,ITGB2,CD74,ITGAV,TLN1
2.628e-02	-3.64	phosphoprotein binding	molecular function	GO:0051219	93	2	18094	49	HCK,PTPN6
2.630e-02	-3.64	stomach	COSMIC cancer mutations	stomach	15550	46	16828	46	GAB1,PTPN12,MCOLN2,CCND2,RGL1,SH2B3,BMP2K,CD68,ELF4,DOCK8,WDFY3,PLXND1,ITGAV,HCK,PTGIR,TLN1,SLC9A7,ITGB2,RXRA,RBPJ,EHD4,BTG1,ZFP36L1,RBM47,ANTXR2,PTPN6,SPI1,ITGAL,ME1,HEPHL1,TMSB4X,STAB1,TFEB,PREX1,ITM2B,DNM2,ARHGEF18,FKBP5,CD74,AKAP13,ARHGAP24,DAB2,ARAP1,DOCK2,MYO1F,DISC1
2.631e-02	-3.64	PRPSAP2 (phosphoribosyl pyrophosphate synthetase associated protein 2)	protein interactions	5636	98	2	19454	50	PTPN12,HCK
2.639e-02	-3.63	VWFA	prosite domains	PS50234	67	2	12186	46	ANTXR2,ITGAL
2.644e-02	-3.63	RHOQ (ras homolog family member Q)	protein interactions	23433	441	4	19454	50	DOCK8,ITM2B,GAB1,ITGAV
2.649e-02	-3.63	DYNAMIN	prints domains	PR00195	7	1	5227	20	DNM2
2.660e-02	-3.63	positive regulation of fibroblast apoptotic process	biological process	GO:2000271	10	1	18204	49	BTG1
2.660e-02	-3.63	integrin activation	biological process	GO:0033622	10	1	18204	49	TLN1
2.660e-02	-3.63	positive regulation of ATP biosynthetic process	biological process	GO:2001171	10	1	18204	49	TMSB4X
2.660e-02	-3.63	dorsal aorta development	biological process	GO:0035907	10	1	18204	49	RBPJ
2.660e-02	-3.63	establishment of lymphocyte polarity	biological process	GO:0001767	10	1	18204	49	DOCK2
2.660e-02	-3.63	cellular response to X-ray	biological process	GO:0071481	10	1	18204	49	CCND2
2.660e-02	-3.63	negative regulation of mast cell activation	biological process	GO:0033004	10	1	18204	49	PTPN6
2.660e-02	-3.63	cellular response to salt stress	biological process	GO:0071472	10	1	18204	49	ZFP36L1
2.660e-02	-3.63	sequestering of actin monomers	biological process	GO:0042989	10	1	18204	49	TMSB4X
2.660e-02	-3.63	regulation of vitamin D receptor signaling pathway	biological process	GO:0070562	10	1	18204	49	RXRA
2.660e-02	-3.63	sebaceous gland development	biological process	GO:0048733	10	1	18204	49	RBPJ
2.660e-02	-3.63	transferrin transport	biological process	GO:0033572	10	1	18204	49	DNM2
2.660e-02	-3.63	synaptic vesicle budding from presynaptic endocytic zone membrane	biological process	GO:0016185	10	1	18204	49	DNM2
2.660e-02	-3.63	endothelial cell chemotaxis	biological process	GO:0035767	10	1	18204	49	GAB1
2.660e-02	-3.63	aggrephagy	biological process	GO:0035973	10	1	18204	49	WDFY3
2.662e-02	-3.63	metal ion transport	biological process	GO:0030001	630	5	18204	49	MCOLN2,DNM2,HEPHL1,SLC9A7,ITGAV
2.668e-02	-3.62	Plexin	interpro domains	IPR031148	10	1	18521	50	PLXND1
2.668e-02	-3.62	Cyclins_cyclin-box	interpro domains	IPR048258	10	1	18521	50	CCND2
2.669e-02	-3.62	microvillus	cellular component	GO:0005902	99	2	19108	49	ITGAV,MYO1F
2.676e-02	-3.62	prostaglandin receptor activity	molecular function	GO:0004955	10	1	18094	49	PTGIR
2.676e-02	-3.62	AP-2 adaptor complex binding	molecular function	GO:0035612	10	1	18094	49	BMP2K
2.676e-02	-3.62	FK506 binding	molecular function	GO:0005528	10	1	18094	49	FKBP5
2.680e-02	-3.62	Flnb (filamin, beta)	protein interactions	286940	99	2	19454	50	DAB2,BMP2K
2.680e-02	-3.62	PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1)	protein interactions	5635	99	2	19454	50	HCK,PTPN12
2.680e-02	-3.62	LMTK2 (lemur tyrosine kinase 2)	protein interactions	22853	99	2	19454	50	PTPN12,PTPN6
2.704e-02	-3.61	transition metal ion transport	biological process	GO:0000041	95	2	18204	49	HEPHL1,DNM2
2.715e-02	-3.61	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	44	16828	46	AKAP13,ARHGEF18,FKBP5,CD74,DAB2,ARHGAP24,ARAP1,DOCK2,MYO1F,TFEB,STAB1,PREX1,ITM2B,DNM2,HEPHL1,TMSB4X,ITGAL,SPI1,ME1,EHD4,BTG1,ZFP36L1,PTPN6,RBM47,ANTXR2,ITGAV,HCK,SLC9A7,TLN1,PTGIR,ITGB2,RXRA,CD68,BMP2K,ELF4,DOCK8,WDFY3,PLXND1,GAB1,PTPN12,MCOLN2,CCND2,SH2B3,RGL1
2.717e-02	-3.61	MYH9 (myosin heavy chain 9)	protein interactions	4627	663	5	19454	50	PTPN6,DAB2,RXRA,ARHGAP24,BMP2K
2.717e-02	-3.61	PTPc_motif	smart domains	SM00404	61	2	9717	41	PTPN6,PTPN12
2.718e-02	-3.61	regulation of hemopoiesis	biological process	GO:1903706	425	4	18204	49	ZFP36L1,SPI1,PTPN6,CD74
2.720e-02	-3.60	EF-hand_4	pfam domains	PF12763	10	1	17795	49	EHD4
2.731e-02	-3.60	SKIC3 (SKI3 subunit of superkiller complex)	protein interactions	9652	100	2	19454	50	FKBP5,TLN1
2.731e-02	-3.60	TTI1 (TELO2 interacting protein 1)	protein interactions	9675	100	2	19454	50	CD68,FKBP5
2.731e-02	-3.60	LRCH3 (leucine rich repeats and calponin homology domain containing 3)	protein interactions	84859	100	2	19454	50	DOCK8,SEPTIN9
2.731e-02	-3.60	SUFU (SUFU negative regulator of hedgehog signaling)	protein interactions	51684	100	2	19454	50	DISC1,RBPJ
2.731e-02	-3.60	ANXA6 (annexin A6)	protein interactions	309	100	2	19454	50	DOCK8,ARHGAP24
2.737e-02	-3.60	response to lipid	biological process	GO:0033993	862	6	18204	49	HCK,CD68,PTGIR,ZFP36L1,DAB2,RXRA
2.737e-02	-3.60	Viral myocarditis	KEGG pathways	hsa05416	58	2	7161	32	ITGAL,ITGB2
2.747e-02	-3.59	Endocytosis	KEGG pathways	hsa04144	260	4	7161	32	EHD4,ARAP1,DAB2,DNM2
2.747e-02	-3.59	Endocytosis	KEGG pathways	ko04144	260	4	7161	32	EHD4,ARAP1,DNM2,DAB2
2.748e-02	-3.59	STX17 (syntaxin 17)	protein interactions	55014	254	3	19454	50	PTPN12,ME1,HEPHL1
2.752e-02	-3.59	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	11	19108	49	PREX1,SEPTIN9,ARHGAP45,DOCK8,WDFY3,TLN1,ITGAV,MYO1F,PLXND1,DNM2,DISC1
2.756e-02	-3.59	negative regulation of response to wounding	biological process	GO:1903035	96	2	18204	49	SH2B3,PTPN6
2.756e-02	-3.59	regulation of stem cell proliferation	biological process	GO:0072091	96	2	18204	49	RBPJ,ZFP36L1
2.767e-02	-3.59	Cross-presentation of particulate exogenous antigens (phagosomes)	REACTOME pathways	R-HSA-1236973	8	1	10285	36	ITGAV
2.779e-02	-3.58	PINK1 (PTEN induced kinase 1)	protein interactions	65018	667	5	19454	50	SEPTIN9,HEPHL1,FKBP5,EHD4,TLN1
2.780e-02	-3.58	regulation of inflammatory response	biological process	GO:0050727	428	4	18204	49	PTPN6,ELF4,TMSB4X,HCK
2.781e-02	-3.58	PRKCG (protein kinase C gamma)	protein interactions	5582	101	2	19454	50	ITGB2,DAB2
2.781e-02	-3.58	KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2)	protein interactions	11014	101	2	19454	50	HEPHL1,CCND2
2.781e-02	-3.58	DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1)	protein interactions	1780	101	2	19454	50	DISC1,DNM2
2.792e-02	-3.58	LAT2 (linker for activation of T cells family member 2)	protein interactions	7462	11	1	19454	50	GAB1
2.792e-02	-3.58	FMO1 (flavin containing dimethylaniline monoxygenase 1)	protein interactions	2326	11	1	19454	50	TLN1
2.792e-02	-3.58	CCDC141 (coiled-coil domain containing 141)	protein interactions	285025	11	1	19454	50	DISC1
2.792e-02	-3.58	Fcho2 (FCH domain only 2)	protein interactions	218503	11	1	19454	50	DAB2
2.792e-02	-3.58	ZNF726 (zinc finger protein 726)	protein interactions	730087	11	1	19454	50	ARHGAP24
2.792e-02	-3.58	NYAP1 (neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1)	protein interactions	222950	11	1	19454	50	TLN1
2.792e-02	-3.58	RGCC (regulator of cell cycle)	protein interactions	28984	11	1	19454	50	TLN1
2.792e-02	-3.58	MS4A7 (membrane spanning 4-domains A7)	protein interactions	58475	11	1	19454	50	ITGB2
2.813e-02	-3.57	anaplastic_carcinoma	COSMIC cancer mutations	anaplastic_carcinoma	856	6	16828	46	DOCK2,DOCK8,PTGIR,ELF4,DAB2,HEPHL1
2.813e-02	-3.57	thyroid-carcinoma-anaplastic_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-anaplastic_carcinoma	856	6	16828	46	PTGIR,HEPHL1,DAB2,ELF4,DOCK2,DOCK8
2.819e-02	-3.57	KRT31 (keratin 31)	protein interactions	3881	450	4	19454	50	TMSB4X,HCK,DOCK2,ITGB2
2.825e-02	-3.57	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	13	16828	46	GAB1,STAB1,MCOLN2,AKAP13,TFEB,ARHGEF18,PREX1,ARHGAP24,MYO1F,DOCK2,WDFY3,ME1,RGL1
2.832e-02	-3.56	human chr9p24.3	chromosome location	human chr9p24.3	15	1	26134	50	DOCK8
2.832e-02	-3.56	human chr12q21.33	chromosome location	human chr12q21.33	15	1	26134	50	BTG1
2.832e-02	-3.56	FASLG (Fas ligand)	protein interactions	356	102	2	19454	50	HCK,FYB1
2.832e-02	-3.56	GRAP2 (GRB2 related adaptor protein 2)	protein interactions	9402	102	2	19454	50	DNM2,GAB1
2.832e-02	-3.56	NFYA (nuclear transcription factor Y subunit alpha)	protein interactions	4800	102	2	19454	50	ME1,SPI1
2.832e-02	-3.56	NTNG1 (netrin G1)	protein interactions	22854	102	2	19454	50	TLN1,EHD4
2.842e-02	-3.56	RHOF (ras homolog family member F, filopodia associated)	protein interactions	54509	671	5	19454	50	EHD4,DAB2,DOCK8,GAB1,ITGAV
2.853e-02	-3.56	bone-femur-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-femur-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	633	5	16828	46	ELF4,HEPHL1,PREX1,STAB1,AKAP13
2.858e-02	-3.56	CDK9 (cyclin dependent kinase 9)	protein interactions	1025	672	5	19454	50	SEPTIN9,FKBP5,DNM2,HCK,PTPN6
2.877e-02	-3.55	regulation of leukocyte mediated immunity	biological process	GO:0002703	247	3	18204	49	ITGB2,SPI1,PTPN6
2.879e-02	-3.55	FLOT1 (flotillin 1)	protein interactions	10211	453	4	19454	50	DISC1,ELF4,GAB1,SEPTIN9
2.884e-02	-3.55	GADD45A (growth arrest and DNA damage inducible alpha)	protein interactions	1647	103	2	19454	50	RBPJ,RXRA
2.886e-02	-3.55	prostate	COSMIC cancer mutations	prostate	13883	43	16828	46	DOCK8,WDFY3,PLXND1,BMP2K,HEPHL1,ELF4,ITGAL,SPI1,ME1,RGL1,SH2B3,GAB1,PTPN12,MCOLN2,CCND2,ARAP1,MYO1F,ZFP36L1,DOCK2,DISC1,PTPN6,RBM47,ANTXR2,AKAP13,EHD4,FKBP5,ARHGEF18,RBPJ,DAB2,BTG1,ARHGAP24,ITM2B,ITGB2,DNM2,RXRA,ITGAV,STAB1,TFEB,HCK,TLN1,SLC9A7,PREX1,PTGIR
2.893e-02	-3.54	BTG Family Proteins and Cell Cycle Regulation	SMPDB pathways	SMP0063773	10	1	1369	4	BTG1
2.900e-02	-3.54	PSMC5 (proteasome 26S subunit, ATPase 5)	protein interactions	5705	454	4	19454	50	PTPN6,TLN1,CCND2,RXRA
2.917e-02	-3.53	Integrin_B_tail	smart domains	SM01242	7	1	9717	41	ITGB2
2.917e-02	-3.53	DYNc	smart domains	SM00053	7	1	9717	41	DNM2
2.917e-02	-3.53	activation of GTPase activity	biological process	GO:0090630	99	2	18204	49	ARHGAP45,ARHGAP24
2.922e-02	-3.53	negative regulation of myeloid leukocyte mediated immunity	biological process	GO:0002887	11	1	18204	49	SPI1
2.922e-02	-3.53	blood vessel endothelial cell differentiation	biological process	GO:0060837	11	1	18204	49	RBPJ
2.922e-02	-3.53	pyramidal neuron development	biological process	GO:0021860	11	1	18204	49	DISC1
2.922e-02	-3.53	negative regulation of humoral immune response mediated by circulating immunoglobulin	biological process	GO:0002924	11	1	18204	49	PTPN6
2.922e-02	-3.53	regulation of non-motile cilium assembly	biological process	GO:1902855	11	1	18204	49	SEPTIN9
2.922e-02	-3.53	synaptic vesicle budding	biological process	GO:0070142	11	1	18204	49	DNM2
2.922e-02	-3.53	negative regulation of platelet aggregation	biological process	GO:0090331	11	1	18204	49	SH2B3
2.922e-02	-3.53	positive regulation of steroid hormone secretion	biological process	GO:2000833	11	1	18204	49	DAB2
2.922e-02	-3.53	regulation of chemokine (C-C motif) ligand 5 production	biological process	GO:0071649	11	1	18204	49	MCOLN2
2.922e-02	-3.53	cardiac muscle cell myoblast differentiation	biological process	GO:0060379	11	1	18204	49	RBPJ
2.922e-02	-3.53	pericyte cell differentiation	biological process	GO:1904238	11	1	18204	49	SPI1
2.922e-02	-3.53	secondary heart field specification	biological process	GO:0003139	11	1	18204	49	RBPJ
2.923e-02	-3.53	Signaling by SCF-KIT	REACTOME pathways	R-HSA-1433557	337	4	10285	36	SH2B3,PTPN6,GAB1,TLN1
2.931e-02	-3.53	Integrin_alpha_Ig-like_3	interpro domains	IPR048286	11	1	18521	50	ITGAV
2.931e-02	-3.53	PKD1_2_channel	interpro domains	IPR013122	11	1	18521	50	MCOLN2
2.931e-02	-3.53	Cation/H_exchanger_CPA1	interpro domains	IPR018422	11	1	18521	50	SLC9A7
2.931e-02	-3.53	EH_dom	interpro domains	IPR000261	11	1	18521	50	EHD4
2.940e-02	-3.53	complement component C3b binding	molecular function	GO:0001851	11	1	18094	49	ITGB2
2.940e-02	-3.53	nitric-oxide synthase binding	molecular function	GO:0050998	11	1	18094	49	CD74
2.940e-02	-3.53	T cell receptor binding	molecular function	GO:0042608	11	1	18094	49	DOCK2
2.940e-02	-3.53	STAT family protein binding	molecular function	GO:0097677	11	1	18094	49	SPI1
2.940e-02	-3.53	prostanoid receptor activity	molecular function	GO:0004954	11	1	18094	49	PTGIR
2.947e-02	-3.52	BEACH domain	gene3d domains	1.10.1540.10	9	1	14470	48	WDFY3
2.956e-02	-3.52	positive regulation of cellular component organization	biological process	GO:0051130	1122	7	18204	49	DOCK2,SEPTIN9,DAB2,HCK,DISC1,PLXND1,ARAP1
2.981e-02	-3.51	PH_BEACH	prosite domains	PS51783	8	1	12186	46	WDFY3
2.981e-02	-3.51	TH1	prosite domains	PS51757	8	1	12186	46	MYO1F
2.988e-02	-3.51	TRIP10 (thyroid hormone receptor interactor 10)	protein interactions	9322	105	2	19454	50	DNM2,RXRA
2.988e-02	-3.51	XPNPEP1 (X-prolyl aminopeptidase 1)	protein interactions	7511	105	2	19454	50	DISC1,RBPJ
2.988e-02	-3.51	Integrin_A_Ig_3	pfam domains	PF20806	11	1	17795	49	ITGAV
2.988e-02	-3.51	PKD_channel	pfam domains	PF08016	11	1	17795	49	MCOLN2
3.005e-02	-3.50	protein tyrosine phosphatase activity	molecular function	GO:0004725	100	2	18094	49	PTPN6,PTPN12
3.013e-02	-3.50	trans-Golgi network	cellular component	GO:0005802	264	3	19108	49	SLC9A7,CD74,ARAP1
3.014e-02	-3.50	TYR_PHOSPHATASE_1	prosite domains	PS00383	72	2	12186	46	PTPN12,PTPN6
3.016e-02	-3.50	PML (PML nuclear body scaffold)	protein interactions	5371	923	6	19454	50	DNM2,SPI1,TLN1,SEPTIN9,ELF4,RXRA
3.022e-02	-3.50	INTEGRINB	prints domains	PR01186	8	1	5227	20	ITGB2
3.022e-02	-3.50	PROSTANOIDR	prints domains	PR01788	8	1	5227	20	PTGIR
3.023e-02	-3.50	IGF1R (insulin like growth factor 1 receptor)	protein interactions	3480	460	4	19454	50	ITGAV,GAB1,PTPN6,PTPN12
3.027e-02	-3.50	platelet activation	biological process	GO:0030168	101	2	18204	49	PTPN6,TLN1
3.033e-02	-3.50	PFKP (phosphofructokinase, platelet)	protein interactions	5214	264	3	19454	50	GAB1,ARHGAP24,PTPN6
3.038e-02	-3.49	FBXW7 (F-box and WD repeat domain containing 7)	protein interactions	55294	1181	7	19454	50	FKBP5,SPI1,BTG1,ITGAV,DISC1,AKAP13,DNM2
3.040e-02	-3.49	HSP90AB2P (heat shock protein 90 alpha family class B member 2, pseudogene)	protein interactions	391634	106	2	19454	50	HCK,FKBP5
3.040e-02	-3.49	SGCA (sarcoglycan alpha)	protein interactions	6442	106	2	19454	50	DNM2,ITM2B
3.042e-02	-3.49	FCRL5 (Fc receptor like 5)	protein interactions	83416	12	1	19454	50	ME1
3.042e-02	-3.49	ZNF91 (zinc finger protein 91)	protein interactions	7644	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	AMPD3 (adenosine monophosphate deaminase 3)	protein interactions	272	12	1	19454	50	ITGB2
3.042e-02	-3.49	C8orf76 (chromosome 8 open reading frame 76)	protein interactions	84933	12	1	19454	50	DISC1
3.042e-02	-3.49	PNMT (phenylethanolamine N-methyltransferase)	protein interactions	5409	12	1	19454	50	HCK
3.042e-02	-3.49	TM7SF2 (transmembrane 7 superfamily member 2)	protein interactions	7108	12	1	19454	50	DISC1
3.042e-02	-3.49	RWDD1 (RWD domain containing 1)	protein interactions	51389	12	1	19454	50	CD74
3.042e-02	-3.49	PDE6G (phosphodiesterase 6G)	protein interactions	5148	12	1	19454	50	DNM2
3.042e-02	-3.49	ANO5 (anoctamin 5)	protein interactions	203859	12	1	19454	50	PTGIR
3.042e-02	-3.49	TENM4 (teneurin transmembrane protein 4)	protein interactions	26011	12	1	19454	50	DOCK2
3.042e-02	-3.49	TNXB (tenascin XB)	protein interactions	7148	12	1	19454	50	SEPTIN9
3.042e-02	-3.49	LOC102724560 (cystathionine beta-synthase like)	protein interactions	102724560	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	SSTR2 (somatostatin receptor 2)	protein interactions	6752	12	1	19454	50	PTPN6
3.042e-02	-3.49	ROBO4 (roundabout guidance receptor 4)	protein interactions	54538	12	1	19454	50	RXRA
3.042e-02	-3.49	PTPN20 (protein tyrosine phosphatase non-receptor type 20)	protein interactions	26095	12	1	19454	50	PTPN6
3.042e-02	-3.49	NUDT4 (nudix hydrolase 4)	protein interactions	11163	12	1	19454	50	DISC1
3.042e-02	-3.49	THAP2 (THAP domain containing 2)	protein interactions	83591	12	1	19454	50	PTPN12
3.042e-02	-3.49	Cep350 (centrosomal protein 350)	protein interactions	74081	12	1	19454	50	TLN1
3.042e-02	-3.49	ITGB6 (integrin subunit beta 6)	protein interactions	3694	12	1	19454	50	ITGAV
3.042e-02	-3.49	ABCB5 (ATP binding cassette subfamily B member 5)	protein interactions	340273	12	1	19454	50	CCND2
3.042e-02	-3.49	ROPN1L (rhophilin associated tail protein 1 like)	protein interactions	83853	12	1	19454	50	CD74
3.042e-02	-3.49	ZNF235 (zinc finger protein 235)	protein interactions	9310	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	FUT4 (fucosyltransferase 4)	protein interactions	2526	12	1	19454	50	ITGB2
3.042e-02	-3.49	ZNF268 (zinc finger protein 268)	protein interactions	10795	12	1	19454	50	RBPJ
3.044e-02	-3.49	Prot-tyrosine_phosphatase-like	interpro domains	IPR029021	101	2	18521	50	PTPN6,PTPN12
3.056e-02	-3.49	C1	smart domains	SM00109	65	2	9717	41	AKAP13,ARHGAP45
3.062e-02	-3.49	OSBPL8 (oxysterol binding protein like 8)	protein interactions	114882	265	3	19454	50	PTGIR,CD74,DISC1
3.071e-02	-3.48	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	35	16828	46	DAB2,ARHGAP24,AKAP13,EHD4,ARHGEF18,FKBP5,CD74,PTPN6,ANTXR2,ARAP1,DOCK2,MYO1F,SLC9A7,TLN1,PREX1,ITGAV,STAB1,DNM2,RXRA,HEPHL1,ELF4,CD68,BMP2K,PLXND1,DOCK8,WDFY3,CCND2,GAB1,MCOLN2,PTPN12,ME1,RGL1,SH2B3,ITGAL,SPI1
3.071e-02	-3.48	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	35	16828	46	ITGAV,STAB1,PREX1,TLN1,SLC9A7,RXRA,DNM2,ARHGEF18,FKBP5,CD74,EHD4,AKAP13,ARHGAP24,DAB2,ARAP1,MYO1F,DOCK2,ANTXR2,PTPN6,GAB1,MCOLN2,PTPN12,CCND2,SPI1,ITGAL,ME1,SH2B3,RGL1,BMP2K,CD68,HEPHL1,ELF4,DOCK8,WDFY3,PLXND1
3.082e-02	-3.48	artery development	biological process	GO:0060840	102	2	18204	49	RBPJ,PLXND1
3.082e-02	-3.48	alpha-beta T cell activation	biological process	GO:0046631	102	2	18204	49	ELF4,DOCK2
3.093e-02	-3.48	TFAP2A (transcription factor AP-2 alpha)	protein interactions	7020	107	2	19454	50	DAB2,RBPJ
3.093e-02	-3.48	POLR3C (RNA polymerase III subunit C)	protein interactions	10623	107	2	19454	50	DISC1,RBPJ
3.093e-02	-3.48	APLP2 (amyloid beta precursor like protein 2)	protein interactions	334	107	2	19454	50	DAB2,DISC1
3.101e-02	-3.47	regulation of neuron projection development	biological process	GO:0010975	443	4	18204	49	PREX1,DAB2,DISC1,PLXND1
3.103e-02	-3.47	Nectin adhesion pathway	Pathway Interaction DB	nectin_pathway	25	2	2226	25	ITGAV,TLN1
3.108e-02	-3.47	Prostanoid ligand receptors	REACTOME pathways	R-HSA-391908	9	1	10285	36	PTGIR
3.108e-02	-3.47	Sodium/Proton exchangers	REACTOME pathways	R-HSA-425986	9	1	10285	36	SLC9A7
3.108e-02	-3.47	PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	REACTOME pathways	R-HSA-8849469	9	1	10285	36	ARAP1
3.114e-02	-3.47	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	11	16828	46	ITGAL,ME1,PTPN12,GAB1,ITGAV,SLC9A7,TLN1,DOCK2,PLXND1,AKAP13,ARHGAP24
3.114e-02	-3.47	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	11	16828	46	ITGAV,GAB1,PTPN12,AKAP13,ARHGAP24,TLN1,SLC9A7,DOCK2,ITGAL,ME1,PLXND1
3.120e-02	-3.47	positive regulation of T cell activation	biological process	GO:0050870	255	3	18204	49	DOCK8,PTPN6,CD74
3.138e-02	-3.46	regulation of biomineral tissue development	biological process	GO:0070167	103	2	18204	49	RXRA,BMP2K
3.147e-02	-3.46	CDK15 (cyclin dependent kinase 15)	protein interactions	65061	108	2	19454	50	FKBP5,ME1
3.147e-02	-3.46	PTK7 (protein tyrosine kinase 7 (inactive))	protein interactions	5754	108	2	19454	50	PTPN6,PTPN12
3.147e-02	-3.46	PYGL (glycogen phosphorylase L)	protein interactions	5836	108	2	19454	50	FKBP5,ARHGAP24
3.151e-02	-3.46	VCL (vinculin)	protein interactions	7414	268	3	19454	50	ARHGAP24,TLN1,PTPN12
3.151e-02	-3.46	NSUN2 (NOP2/Sun RNA methyltransferase 2)	protein interactions	54888	268	3	19454	50	TLN1,FKBP5,ARHGAP24
3.151e-02	-3.46	protein complex oligomerization	biological process	GO:0051259	256	3	18204	49	CD74,EHD4,ME1
3.156e-02	-3.46	Ig_E-set	interpro domains	IPR014756	103	2	18521	50	PLXND1,RBPJ
3.159e-02	-3.45	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	7	16828	46	ITM2B,ZFP36L1,DOCK8,AKAP13,BTG1,SLC9A7,TLN1
3.160e-02	-3.45	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	43	16828	46	BTG1,ARHGAP24,DAB2,ARHGEF18,FKBP5,CD74,RBPJ,AKAP13,EHD4,RBM47,ANTXR2,DISC1,PTPN6,ARAP1,ZFP36L1,MYO1F,DOCK2,PTGIR,PREX1,SLC9A7,TLN1,ITGAV,HCK,STAB1,TFEB,RXRA,DNM2,ITM2B,ITGB2,HEPHL1,ELF4,BMP2K,PLXND1,WDFY3,DOCK8,CCND2,GAB1,MCOLN2,PTPN12,ME1,RGL1,SPI1,ITGAL
3.160e-02	-3.45	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	43	16828	46	ITGAL,SPI1,ME1,HEPHL1,STAB1,TFEB,PREX1,ITM2B,DNM2,AKAP13,ARHGEF18,FKBP5,CD74,DAB2,ARHGAP24,ARAP1,MYO1F,DOCK2,DISC1,GAB1,PTPN12,MCOLN2,CCND2,RGL1,BMP2K,ELF4,DOCK8,WDFY3,PLXND1,ITGAV,HCK,SLC9A7,TLN1,PTGIR,ITGB2,RXRA,EHD4,RBPJ,BTG1,ZFP36L1,PTPN6,RBM47,ANTXR2
3.160e-02	-3.45	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	11	16828	46	HCK,TFEB,STAB1,BMP2K,DAB2,HEPHL1,ARHGAP24,BTG1,ITGAL,SPI1,PLXND1
3.172e-02	-3.45	anatomical structure morphogenesis	biological process	GO:0009653	2225	11	18204	49	ITGAV,ARHGAP24,ZFP36L1,SPI1,PLXND1,ITGB2,RBPJ,PTPN6,DOCK2,GAB1,DNM2
3.181e-02	-3.45	AP2A1 (adaptor related protein complex 2 subunit alpha 1)	protein interactions	160	269	3	19454	50	BMP2K,DAB2,DNM2
3.184e-02	-3.45	lymphoid progenitor cell differentiation	biological process	GO:0002320	12	1	18204	49	SPI1
3.184e-02	-3.45	regulation of chemokine-mediated signaling pathway	biological process	GO:0070099	12	1	18204	49	SH2B3
3.184e-02	-3.45	heart field specification	biological process	GO:0003128	12	1	18204	49	RBPJ
3.184e-02	-3.45	regulation of prostaglandin biosynthetic process	biological process	GO:0031392	12	1	18204	49	CD74
3.184e-02	-3.45	endocardium development	biological process	GO:0003157	12	1	18204	49	RBPJ
3.184e-02	-3.45	cytidine to uridine editing	biological process	GO:0016554	12	1	18204	49	RBM47
3.184e-02	-3.45	endothelial tube morphogenesis	biological process	GO:0061154	12	1	18204	49	RBPJ
3.184e-02	-3.45	regulation of inflammatory response to wounding	biological process	GO:0106014	12	1	18204	49	PTPN6
3.184e-02	-3.45	morphogenesis of an endothelium	biological process	GO:0003159	12	1	18204	49	RBPJ
3.184e-02	-3.45	regulation of timing of cell differentiation	biological process	GO:0048505	12	1	18204	49	RBPJ
3.186e-02	-3.45	PML body	cellular component	GO:0016605	109	2	19108	49	WDFY3,ELF4
3.187e-02	-3.45	TUBA1A (tubulin alpha 1a)	protein interactions	7846	692	5	19454	50	TLN1,FKBP5,CD74,BTG1,ARHGAP24
3.189e-02	-3.45	Signaling events mediated by VEGFR1 and VEGFR2	Pathway Interaction DB	vegfr1_2_pathway	63	3	2226	25	GAB1,PTPN6,ITGAV
3.194e-02	-3.44	epithelial cell migration	biological process	GO:0010631	104	2	18204	49	GAB1,PLXND1
3.194e-02	-3.44	positive regulation of ubiquitin-dependent protein catabolic process	biological process	GO:2000060	104	2	18204	49	DAB2,DISC1
3.194e-02	-3.44	regulation of chemokine production	biological process	GO:0032642	104	2	18204	49	MCOLN2,CD74
3.194e-02	-3.44	protein polymerization	biological process	GO:0051258	104	2	18204	49	DNM2,PREX1
3.200e-02	-3.44	MBP (myelin basic protein)	protein interactions	4155	109	2	19454	50	BMP2K,ARHGAP24
3.200e-02	-3.44	NT5C2 (5'-nucleotidase, cytosolic II)	protein interactions	22978	109	2	19454	50	ELF4,EHD4
3.203e-02	-3.44	MAP-kinase scaffold activity	molecular function	GO:0005078	12	1	18094	49	AKAP13
3.203e-02	-3.44	vinculin binding	molecular function	GO:0017166	12	1	18094	49	TLN1
3.203e-02	-3.44	macrolide binding	molecular function	GO:0005527	12	1	18094	49	FKBP5
3.203e-02	-3.44	semaphorin receptor activity	molecular function	GO:0017154	12	1	18094	49	PLXND1
3.211e-02	-3.44	PTCH1 (patched 1)	protein interactions	5727	270	3	19454	50	PLXND1,ITGAV,CD74
3.213e-02	-3.44	VCAM1 (vascular cell adhesion molecule 1)	protein interactions	7412	469	4	19454	50	DNM2,ARAP1,WDFY3,TLN1
3.231e-02	-3.43	von Willebrand factor, type A domain	gene3d domains	3.40.50.410	85	2	14470	48	ITGB2,ANTXR2
3.232e-02	-3.43	bone-sacrum-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-sacrum-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	12	1	16828	46	STAB1
3.235e-02	-3.43	H2AC4 (H2A clustered histone 4)	protein interactions	8335	470	4	19454	50	DNM2,EHD4,CCND2,PTPN6
3.235e-02	-3.43	regulation of innate immune response	biological process	GO:0045088	449	4	18204	49	PTPN6,RBM47,SPI1,HCK
3.251e-02	-3.43	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	biological process	GO:0090100	105	2	18204	49	RBPJ,DAB2
3.251e-02	-3.43	positive regulation of myeloid cell differentiation	biological process	GO:0045639	105	2	18204	49	CD74,ZFP36L1
3.251e-02	-3.43	response to type II interferon	biological process	GO:0034341	105	2	18204	49	CD74,HCK
3.251e-02	-3.43	antigen processing and presentation	biological process	GO:0019882	105	2	18204	49	CD74,DNM2
3.254e-02	-3.43	CFTR (CF transmembrane conductance regulator)	protein interactions	1080	1469	8	19454	50	TLN1,DNM2,CD68,SEPTIN9,TFEB,DAB2,ANTXR2,ITGAV
3.256e-02	-3.42	intracellular organelle	cellular component	GO:0043229	13594	41	19108	49	PTPN12,HCK,ITGB2,ARHGAP45,ARAP1,DISC1,PTPN6,BTG1,CD74,ME1,STAB1,FKBP5,SEPTIN9,AKAP13,BMP2K,ITM2B,DAB2,RBPJ,DNM2,TFEB,MYO1F,CD68,TLN1,ITGAV,RXRA,ELF4,SLC9A7,RBM47,DOCK2,ZFP36L1,ARHGEF18,ITGAL,CCND2,FYB1,EHD4,TMSB4X,WDFY3,ANTXR2,ARHGAP24,MCOLN2,SPI1
3.269e-02	-3.42	Cytochrome c1, transmembrane anchor, C-terminal	gene3d domains	1.20.5.100	10	1	14470	48	ITGB2
3.269e-02	-3.42	-	gene3d domains	6.10.140.1330	10	1	14470	48	SLC9A7
3.281e-02	-3.42	distal axon	cellular component	GO:0150034	273	3	19108	49	PREX1,DNM2,DISC1
3.284e-02	-3.42	semaphorin receptor complex	cellular component	GO:0002116	13	1	19108	49	PLXND1
3.291e-02	-3.41	Septin2 (septin 2)	protein interactions	18000	13	1	19454	50	SEPTIN9
3.291e-02	-3.41	PLEKHH1 (pleckstrin homology, MyTH4 and FERM domain containing H1)	protein interactions	57475	13	1	19454	50	FKBP5
3.291e-02	-3.41	SEMA4A (semaphorin 4A)	protein interactions	64218	13	1	19454	50	PLXND1
3.291e-02	-3.41	PRRX1 (paired related homeobox 1)	protein interactions	5396	13	1	19454	50	FKBP5
3.291e-02	-3.41	FCRL3 (Fc receptor like 3)	protein interactions	115352	13	1	19454	50	PTPN6
3.291e-02	-3.41	CRYGC (crystallin gamma C)	protein interactions	1420	13	1	19454	50	DISC1
3.291e-02	-3.41	C1orf74 (chromosome 1 open reading frame 74)	protein interactions	148304	13	1	19454	50	HCK
3.291e-02	-3.41	PPP1R2B (PPP1R2 family member B)	protein interactions	153743	13	1	19454	50	BMP2K
3.291e-02	-3.41	Notch1 (notch 1)	protein interactions	18128	13	1	19454	50	RBPJ
3.291e-02	-3.41	ZNF718 (zinc finger protein 718)	protein interactions	255403	13	1	19454	50	ARHGAP24
3.293e-02	-3.41	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	11	16828	46	GAB1,ITGAV,PTPN12,SLC9A7,TLN1,ITGAL,ME1,AKAP13,ARHGAP24,DOCK2,PLXND1
3.307e-02	-3.41	regulation of actin filament bundle assembly	biological process	GO:0032231	106	2	18204	49	ARHGEF18,ARAP1
3.309e-02	-3.41	PLP1 (proteolipid protein 1)	protein interactions	5354	111	2	19454	50	CD74,ITGAV
3.327e-02	-3.40	INB	smart domains	SM00187	8	1	9717	41	ITGB2
3.329e-02	-3.40	regulation of MAPK cascade	biological process	GO:0043408	669	5	18204	49	DAB2,PTPN6,SPI1,SH2B3,CD74
3.341e-02	-3.40	immune response-regulating cell surface receptor signaling pathway	biological process	GO:0002768	262	3	18204	49	HCK,PTPN6,FYB1
3.348e-02	-3.40	BRICHOS	prosite domains	PS50869	9	1	12186	46	ITM2B
3.348e-02	-3.40	INTEGRIN_BETA	prosite domains	PS00243	9	1	12186	46	ITGB2
3.348e-02	-3.40	BEACH	prosite domains	PS50197	9	1	12186	46	WDFY3
3.349e-02	-3.40	embryonic organ development	biological process	GO:0048568	454	4	18204	49	TFEB,ZFP36L1,SH2B3,RBPJ
3.363e-02	-3.39	MCAT (malonyl-CoA-acyl carrier protein transacylase)	protein interactions	27349	112	2	19454	50	TFEB,ITGAV
3.363e-02	-3.39	SARS1 (seryl-tRNA synthetase 1)	protein interactions	6301	112	2	19454	50	EHD4,ARHGAP24
3.363e-02	-3.39	C10orf88 (chromosome 10 open reading frame 88)	protein interactions	80007	112	2	19454	50	RBM47,BMP2K
3.365e-02	-3.39	T cell receptor signaling pathway	biological process	GO:0050852	107	2	18204	49	PTPN6,FYB1
3.365e-02	-3.39	epithelium migration	biological process	GO:0090132	107	2	18204	49	GAB1,PLXND1
3.369e-02	-3.39	XPO1 (exportin 1)	protein interactions	7514	1479	8	19454	50	DOCK8,SEPTIN9,TFEB,DAB2,RBPJ,BMP2K,ZFP36L1,ARHGAP24
3.377e-02	-3.39	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	7	16828	46	DOCK8,ZFP36L1,ITM2B,AKAP13,SLC9A7,TLN1,BTG1
3.394e-02	-3.38	NAHEXCHNGR	prints domains	PR01084	9	1	5227	20	SLC9A7
3.394e-02	-3.38	FLNB (filamin B)	protein interactions	2317	276	3	19454	50	PTPN12,FKBP5,SEPTIN9
3.418e-02	-3.38	CARS1 (cysteinyl-tRNA synthetase 1)	protein interactions	833	113	2	19454	50	ARHGAP24,TLN1
3.422e-02	-3.37	cardiac septum development	biological process	GO:0003279	108	2	18204	49	PLXND1,RBPJ
3.435e-02	-3.37	NTRK1 (neurotrophic receptor tyrosine kinase 1)	protein interactions	4914	2058	10	19454	50	GAB1,ITGAV,FKBP5,PTPN12,SEPTIN9,TLN1,PTPN6,DNM2,ARAP1,EHD4
3.443e-02	-3.37	Protein tyrosine phosphatase superfamily	gene3d domains	3.90.190.10	88	2	14470	48	PTPN12,PTPN6
3.444e-02	-3.37	epithelial to mesenchymal transition involved in endocardial cushion formation	biological process	GO:0003198	13	1	18204	49	RBPJ
3.444e-02	-3.37	type II interferon-mediated signaling pathway	biological process	GO:0060333	13	1	18204	49	HCK
3.444e-02	-3.37	cardioblast differentiation	biological process	GO:0010002	13	1	18204	49	RBPJ
3.444e-02	-3.37	atrioventricular canal development	biological process	GO:0036302	13	1	18204	49	RBPJ
3.444e-02	-3.37	negative regulation of homotypic cell-cell adhesion	biological process	GO:0034111	13	1	18204	49	SH2B3
3.444e-02	-3.37	positive regulation of cyclin-dependent protein serine/threonine kinase activity	biological process	GO:0045737	13	1	18204	49	CCND2
3.444e-02	-3.37	defense response to tumor cell	biological process	GO:0002357	13	1	18204	49	SPI1
3.444e-02	-3.37	negative regulation of leukocyte degranulation	biological process	GO:0043301	13	1	18204	49	SPI1
3.444e-02	-3.37	positive regulation of osteoblast proliferation	biological process	GO:0033690	13	1	18204	49	ITGAV
3.444e-02	-3.37	regulation of development, heterochronic	biological process	GO:0040034	13	1	18204	49	RBPJ
3.447e-02	-3.37	MET receptor recycling	REACTOME pathways	R-HSA-8875656	10	1	10285	36	GAB1
3.447e-02	-3.37	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	36	GAB1
3.447e-02	-3.37	SH3_1	pfam domains	PF00018	106	2	17795	49	HCK,MYO1F
3.454e-02	-3.37	G_SEPTIN_dom	interpro domains	IPR030379	13	1	18521	50	SEPTIN9
3.454e-02	-3.37	Septin	interpro domains	IPR016491	13	1	18521	50	SEPTIN9
3.459e-02	-3.36	plasma membrane raft	cellular component	GO:0044853	114	2	19108	49	HCK,ITGB2
3.465e-02	-3.36	insulin-like growth factor I binding	molecular function	GO:0031994	13	1	18094	49	ITGAV
3.474e-02	-3.36	THBS1 (thrombospondin 1)	protein interactions	7057	114	2	19454	50	ITGAV,DISC1
3.474e-02	-3.36	UBE2L6 (ubiquitin conjugating enzyme E2 L6)	protein interactions	9246	114	2	19454	50	DNM2,SEPTIN9
3.488e-02	-3.36	IRS4 (insulin receptor substrate 4)	protein interactions	8471	279	3	19454	50	PTPN6,FKBP5,ARHGAP24
3.490e-02	-3.36	morphogenesis of an epithelium	biological process	GO:0002009	460	4	18204	49	RBPJ,ARHGAP24,PLXND1,ITGAV
3.502e-02	-3.35	VWA	smart domains	SM00327	70	2	9717	41	ITGAL,ANTXR2
3.522e-02	-3.35	Septin	pfam domains	PF00735	13	1	17795	49	SEPTIN9
3.532e-02	-3.34	septin complex	cellular component	GO:0031105	14	1	19108	49	SEPTIN9
3.532e-02	-3.34	uropod	cellular component	GO:0001931	14	1	19108	49	DNM2
3.532e-02	-3.34	septin ring	cellular component	GO:0005940	14	1	19108	49	SEPTIN9
3.537e-02	-3.34	protein localization to membrane	biological process	GO:0072657	462	4	18204	49	EHD4,FYB1,ITGAL,ITGB2
3.540e-02	-3.34	Septin7 (septin 7)	protein interactions	235072	14	1	19454	50	SEPTIN9
3.540e-02	-3.34	MS4A2 (membrane spanning 4-domains A2)	protein interactions	2206	14	1	19454	50	PTPN6
3.540e-02	-3.34	TFEC (transcription factor EC)	protein interactions	22797	14	1	19454	50	TFEB
3.540e-02	-3.34	Tecpr2 (tectonin beta-propeller repeat containing 2)	protein interactions	104859	14	1	19454	50	WDFY3
3.540e-02	-3.34	CSH2 (chorionic somatomammotropin hormone 2)	protein interactions	1443	14	1	19454	50	PTPN12
3.540e-02	-3.34	PTF1A (pancreas associated transcription factor 1a)	protein interactions	256297	14	1	19454	50	RBPJ
3.540e-02	-3.34	DNAJC27 (DnaJ heat shock protein family (Hsp40) member C27)	protein interactions	51277	14	1	19454	50	FKBP5
3.540e-02	-3.34	ZFP2 (ZFP2 zinc finger protein)	protein interactions	80108	14	1	19454	50	PTPN12
3.540e-02	-3.34	LY6G5C (lymphocyte antigen 6 family member G5C)	protein interactions	80741	14	1	19454	50	ITGAV
3.540e-02	-3.34	ST13P4 (ST13, Hsp70 interacting protein pseudogene 4)	protein interactions	145165	14	1	19454	50	CCND2
3.540e-02	-3.34	AZIN2 (antizyme inhibitor 2)	protein interactions	113451	14	1	19454	50	TLN1
3.540e-02	-3.34	Septin11 (septin 11)	protein interactions	52398	14	1	19454	50	SEPTIN9
3.554e-02	-3.34	regulation of protein phosphorylation	biological process	GO:0001932	917	6	18204	49	CCND2,ITGB2,DAB2,PTPN6,CD74,EHD4
3.558e-02	-3.34	STIP1 (stress induced phosphoprotein 1)	protein interactions	10963	960	6	19454	50	DNM2,FKBP5,TLN1,DOCK8,ARHGAP24,ME1
3.559e-02	-3.34	side of membrane	cellular component	GO:0098552	715	5	19108	49	ITGAL,ITGAV,ITGB2,CD74,HCK
3.567e-02	-3.33	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	265	3	16828	46	HCK,SH2B3,BTG1
3.573e-02	-3.33	positive regulation of cellular metabolic process	biological process	GO:0031325	3164	14	18204	49	EHD4,ELF4,ITGB2,TMSB4X,RBM47,SPI1,TFEB,DAB2,MCOLN2,CD74,DNM2,RBPJ,CCND2,RXRA
3.574e-02	-3.33	human chr2q32.1	chromosome location	human chr2q32.1	19	1	26134	50	ITGAV
3.574e-02	-3.33	human chr15q25.3	chromosome location	human chr15q25.3	19	1	26134	50	AKAP13
3.574e-02	-3.33	human chrXq26.1	chromosome location	human chrXq26.1	19	1	26134	50	ELF4
3.583e-02	-3.33	KRT34 (keratin 34)	protein interactions	3885	282	3	19454	50	TMSB4X,HCK,DOCK2
3.586e-02	-3.33	GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1)	protein interactions	26088	116	2	19454	50	DNM2,STAB1
3.586e-02	-3.33	SUCLG1 (succinate-CoA ligase GDP/ADP-forming subunit alpha)	protein interactions	8802	116	2	19454	50	SEPTIN9,ARHGAP24
3.590e-02	-3.33	regulation of response to stress	biological process	GO:0080134	1431	8	18204	49	SH2B3,RBM47,PTPN6,SPI1,TMSB4X,HCK,ELF4,CD74
3.598e-02	-3.32	negative regulation of binding	biological process	GO:0051100	111	2	18204	49	DAB2,DISC1
3.598e-02	-3.32	positive regulation of lipid localization	biological process	GO:1905954	111	2	18204	49	DAB2,RXRA
3.635e-02	-3.31	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	6	19454	50	ZFP36L1,GAB1,CD74,AKAP13,ITGB2,TFEB
3.642e-02	-3.31	LAMC1 (laminin subunit gamma 1)	protein interactions	3915	117	2	19454	50	ANTXR2,DISC1
3.642e-02	-3.31	SYT6 (synaptotagmin 6)	protein interactions	148281	117	2	19454	50	DNM2,EHD4
3.657e-02	-3.31	extrinsic apoptotic signaling pathway	biological process	GO:0097191	112	2	18204	49	SPI1,ITGAV
3.664e-02	-3.31	positive regulation of macromolecule metabolic process	biological process	GO:0010604	3485	15	18204	49	CD74,MCOLN2,DNM2,RBPJ,RXRA,CCND2,ELF4,EHD4,DISC1,ARAP1,SPI1,RBM47,ZFP36L1,DAB2,TFEB
3.699e-02	-3.30	SAMD1 (sterile alpha motif domain containing 1)	protein interactions	90378	118	2	19454	50	TLN1,RBPJ
3.703e-02	-3.30	angioimmunoblastic_T_cell_lymphoma	COSMIC cancer mutations	angioimmunoblastic_T_cell_lymphoma	269	3	16828	46	BTG1,SH2B3,HCK
3.704e-02	-3.30	negative regulation of macrophage derived foam cell differentiation	biological process	GO:0010745	14	1	18204	49	ITGAV
3.704e-02	-3.30	ventricular trabecula myocardium morphogenesis	biological process	GO:0003222	14	1	18204	49	RBPJ
3.704e-02	-3.30	interleukin-6-mediated signaling pathway	biological process	GO:0070102	14	1	18204	49	SPI1
3.704e-02	-3.30	positive regulation of purine nucleotide biosynthetic process	biological process	GO:1900373	14	1	18204	49	TMSB4X
3.704e-02	-3.30	positive regulation of receptor recycling	biological process	GO:0001921	14	1	18204	49	ARAP1
3.704e-02	-3.30	regulation of podosome assembly	biological process	GO:0071801	14	1	18204	49	HCK
3.704e-02	-3.30	positive regulation by symbiont of entry into host	biological process	GO:0075294	14	1	18204	49	CD74
3.704e-02	-3.30	regulation of unsaturated fatty acid biosynthetic process	biological process	GO:2001279	14	1	18204	49	CD74
3.704e-02	-3.30	positive regulation of nucleotide biosynthetic process	biological process	GO:0030810	14	1	18204	49	TMSB4X
3.704e-02	-3.30	cellular response to oxidised low-density lipoprotein particle stimulus	biological process	GO:0140052	14	1	18204	49	CD68
3.704e-02	-3.30	positive regulation of viral entry into host cell	biological process	GO:0046598	14	1	18204	49	CD74
3.713e-02	-3.29	CYCLINS	prosite domains	PS00292	10	1	12186	46	CCND2
3.715e-02	-3.29	Ras_G-nucl-exch_fac_CS	interpro domains	IPR019804	14	1	18521	50	RGL1
3.715e-02	-3.29	Cation/H_exchanger	interpro domains	IPR006153	14	1	18521	50	SLC9A7
3.715e-02	-3.29	Link_dom	interpro domains	IPR000538	14	1	18521	50	STAB1
3.717e-02	-3.29	tissue migration	biological process	GO:0090130	113	2	18204	49	GAB1,PLXND1
3.717e-02	-3.29	regulation of regulated secretory pathway	biological process	GO:1903305	113	2	18204	49	SPI1,ITGB2
3.717e-02	-3.29	positive regulation of plasma membrane bounded cell projection assembly	biological process	GO:0120034	113	2	18204	49	SEPTIN9,ARAP1
3.727e-02	-3.29	potassium:proton antiporter activity	molecular function	GO:0015386	14	1	18094	49	SLC9A7
3.736e-02	-3.29	BRICHOS	smart domains	SM01039	9	1	9717	41	ITM2B
3.736e-02	-3.29	Beach	smart domains	SM01026	9	1	9717	41	WDFY3
3.747e-02	-3.28	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	11	16828	46	PTGIR,PTPN12,STAB1,MCOLN2,RXRA,ITGAL,EHD4,PLXND1,PTPN6,DOCK8,DOCK2
3.756e-02	-3.28	KMT2B (lysine methyltransferase 2B)	protein interactions	9757	119	2	19454	50	RBPJ,ELF4
3.757e-02	-3.28	myelodysplastic-myeloproliferative_neoplasm-unclassifiable	COSMIC cancer mutations	myelodysplastic-myeloproliferative_neoplasm-unclassifiable	112	2	16828	46	SPI1,SH2B3
3.757e-02	-3.28	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable	112	2	16828	46	SH2B3,SPI1
3.759e-02	-3.28	human chr12p13.32	chromosome location	human chr12p13.32	20	1	26134	50	CCND2
3.780e-02	-3.28	cell trailing edge	cellular component	GO:0031254	15	1	19108	49	DNM2
3.785e-02	-3.27	Import of palmitoyl-CoA into the mitochondrial matrix	REACTOME pathways	R-HSA-200425	11	1	10285	36	RXRA
3.785e-02	-3.27	MET activates RAP1 and RAC1	REACTOME pathways	R-HSA-8875555	11	1	10285	36	GAB1
3.785e-02	-3.27	Signaling by FGFR4 in disease	REACTOME pathways	R-HSA-5655291	11	1	10285	36	GAB1
3.788e-02	-3.27	HOXA11 (homeobox A11)	protein interactions	3207	15	1	19454	50	RBPJ
3.788e-02	-3.27	UCP3 (uncoupling protein 3)	protein interactions	7352	15	1	19454	50	RBM47
3.788e-02	-3.27	ZNF813 (zinc finger protein 813)	protein interactions	126017	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	ANGPT2 (angiopoietin 2)	protein interactions	285	15	1	19454	50	ITGAV
3.788e-02	-3.27	ASCL4 (achaete-scute family bHLH transcription factor 4)	protein interactions	121549	15	1	19454	50	DNM2
3.788e-02	-3.27	CASTOR1 (cytosolic arginine sensor for mTORC1 subunit 1)	protein interactions	652968	15	1	19454	50	RXRA
3.788e-02	-3.27	ZNF616 (zinc finger protein 616)	protein interactions	90317	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	OLFM3 (olfactomedin 3)	protein interactions	118427	15	1	19454	50	EHD4
3.788e-02	-3.27	ZNF714 (zinc finger protein 714)	protein interactions	148206	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	Xlink	pfam domains	PF00193	14	1	17795	49	STAB1
3.788e-02	-3.27	Na_H_Exchanger	pfam domains	PF00999	14	1	17795	49	SLC9A7
3.814e-02	-3.27	HOXB9 (homeobox B9)	protein interactions	3219	120	2	19454	50	RBPJ,BTG1
3.814e-02	-3.27	FNBP1 (formin binding protein 1)	protein interactions	23048	120	2	19454	50	DNM2,RBPJ
3.814e-02	-3.27	CD79B (CD79b molecule)	protein interactions	974	120	2	19454	50	PTPN6,WDFY3
3.862e-02	-3.25	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	17	16828	46	FKBP5,AKAP13,DAB2,DOCK2,DOCK8,MYO1F,WDFY3,ZFP36L1,STAB1,TFEB,MCOLN2,ITGAV,GAB1,PREX1,TLN1,ITM2B,RXRA
3.868e-02	-3.25	positive regulation of phosphate metabolic process	biological process	GO:0045937	697	5	18204	49	CCND2,TMSB4X,DAB2,EHD4,CD74
3.868e-02	-3.25	positive regulation of phosphorus metabolic process	biological process	GO:0010562	697	5	18204	49	CCND2,TMSB4X,DAB2,CD74,EHD4
3.910e-02	-3.24	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	48	TLN1
3.934e-02	-3.24	SH3DOMAIN	prints domains	PR00452	83	2	5227	20	MYO1F,HCK
3.935e-02	-3.24	perinuclear region of cytoplasm	cellular component	GO:0048471	735	5	19108	49	DISC1,DAB2,SEPTIN9,PREX1,EHD4
3.942e-02	-3.23	secretory	COSMIC cancer mutations	secretory	115	2	16828	46	WDFY3,ARHGAP24
3.942e-02	-3.23	meninges-meningioma-secretory	COSMIC cancer mutations	meninges-meningioma-secretory	115	2	16828	46	WDFY3,ARHGAP24
3.964e-02	-3.23	negative regulation of androgen receptor signaling pathway	biological process	GO:0060766	15	1	18204	49	DAB2
3.964e-02	-3.23	negative regulation of B cell apoptotic process	biological process	GO:0002903	15	1	18204	49	CD74
3.964e-02	-3.23	negative regulation of DNA damage response, signal transduction by p53 class mediator	biological process	GO:0043518	15	1	18204	49	CD74
3.964e-02	-3.23	positive regulation of hormone metabolic process	biological process	GO:0032352	15	1	18204	49	DAB2
3.964e-02	-3.23	regulation of steroid hormone biosynthetic process	biological process	GO:0090030	15	1	18204	49	DAB2
3.964e-02	-3.23	p38MAPK cascade	biological process	GO:0038066	15	1	18204	49	ZFP36L1
3.964e-02	-3.23	pyramidal neuron differentiation	biological process	GO:0021859	15	1	18204	49	DISC1
3.964e-02	-3.23	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	biological process	GO:1900153	15	1	18204	49	ZFP36L1
3.964e-02	-3.23	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological process	GO:1902166	15	1	18204	49	CD74
3.964e-02	-3.23	positive regulation of monocyte chemotactic protein-1 production	biological process	GO:0071639	15	1	18204	49	MCOLN2
3.964e-02	-3.23	negative regulation of immunoglobulin mediated immune response	biological process	GO:0002890	15	1	18204	49	PTPN6
3.964e-02	-3.23	epithelial cell fate commitment	biological process	GO:0072148	15	1	18204	49	RBPJ
3.964e-02	-3.23	positive regulation of endothelial cell chemotaxis	biological process	GO:2001028	15	1	18204	49	TMSB4X
3.964e-02	-3.23	positive regulation of non-canonical Wnt signaling pathway	biological process	GO:2000052	15	1	18204	49	DAB2
3.964e-02	-3.23	negative regulation of B cell mediated immunity	biological process	GO:0002713	15	1	18204	49	PTPN6
3.975e-02	-3.23	PPIase_FKBP_dom	interpro domains	IPR001179	15	1	18521	50	FKBP5
3.988e-02	-3.22	nuclear vitamin D receptor binding	molecular function	GO:0042809	15	1	18094	49	RXRA
3.988e-02	-3.22	cyclin-dependent protein serine/threonine kinase activator activity	molecular function	GO:0061575	15	1	18094	49	CCND2
3.988e-02	-3.22	icosanoid receptor activity	molecular function	GO:0004953	15	1	18094	49	PTGIR
3.988e-02	-3.22	low-density lipoprotein particle receptor activity	molecular function	GO:0005041	15	1	18094	49	STAB1
3.988e-02	-3.22	1-phosphatidylinositol binding	molecular function	GO:0005545	15	1	18094	49	WDFY3
3.988e-02	-3.22	GNAQ (G protein subunit alpha q)	protein interactions	2776	123	2	19454	50	AKAP13,PTGIR
3.988e-02	-3.22	UBASH3A (ubiquitin associated and SH3 domain containing A)	protein interactions	53347	123	2	19454	50	DNM2,DISC1
3.996e-02	-3.22	TYR_PHOSPHATASE_2	prosite domains	PS50056	84	2	12186	46	PTPN12,PTPN6
4.002e-02	-3.22	calcium channel activity	molecular function	GO:0005262	117	2	18094	49	ITGAV,MCOLN2
4.011e-02	-3.22	RUNX1 (RUNX family transcription factor 1)	protein interactions	861	295	3	19454	50	ELF4,SPI1,CCND2
4.016e-02	-3.21	Platelet homeostasis	REACTOME pathways	R-HSA-418346	91	2	10285	36	PTGIR,PTPN6
4.021e-02	-3.21	multicellular organismal process	biological process	GO:0032501	6177	23	18204	49	DISC1,PLXND1,ITGB2,ITM2B,SPI1,TFEB,ZFP36L1,ITGAL,DNM2,PTPN6,GAB1,ELF4,PREX1,TLN1,SH2B3,ITGAV,ARHGAP24,CD74,DOCK8,AKAP13,RBPJ,DOCK2,CCND2
4.024e-02	-3.21	skin-hip-malignant_melanoma	COSMIC cancer mutations	skin-hip-malignant_melanoma	15	1	16828	46	HEPHL1
4.027e-02	-3.21	septin cytoskeleton	cellular component	GO:0032156	16	1	19108	49	SEPTIN9
4.027e-02	-3.21	T cell receptor complex	cellular component	GO:0042101	16	1	19108	49	PTPN6
4.035e-02	-3.21	SETDB2 (SET domain bifurcated histone lysine methyltransferase 2)	protein interactions	83852	16	1	19454	50	HEPHL1
4.035e-02	-3.21	GPNMB (glycoprotein nmb)	protein interactions	10457	16	1	19454	50	TFEB
4.035e-02	-3.21	DGKQ (diacylglycerol kinase theta)	protein interactions	1609	16	1	19454	50	EHD4
4.035e-02	-3.21	GMPR2 (guanosine monophosphate reductase 2)	protein interactions	51292	16	1	19454	50	ARHGAP24
4.035e-02	-3.21	ZSCAN4 (zinc finger and SCAN domain containing 4)	protein interactions	201516	16	1	19454	50	HCK
4.035e-02	-3.21	SPANXN5 (SPANX family member N5)	protein interactions	494197	16	1	19454	50	EHD4
4.035e-02	-3.21	IL1RL2 (interleukin 1 receptor like 2)	protein interactions	8808	16	1	19454	50	MYO1F
4.035e-02	-3.21	MAML2 (mastermind like transcriptional coactivator 2)	protein interactions	84441	16	1	19454	50	RBPJ
4.035e-02	-3.21	CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2)	protein interactions	729438	16	1	19454	50	RXRA
4.035e-02	-3.21	AKAP6 (A-kinase anchoring protein 6)	protein interactions	9472	16	1	19454	50	DISC1
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	SEPTIN9
4.035e-02	-3.21	TNFRSF25 (TNF receptor superfamily member 25)	protein interactions	8718	16	1	19454	50	PTPN6
4.035e-02	-3.21	PIPOX (pipecolic acid and sarcosine oxidase)	protein interactions	51268	16	1	19454	50	FKBP5
4.037e-02	-3.21	protein kinase binding	molecular function	GO:0019901	701	5	18094	49	CCND2,ITGAV,ITGB2,SH2B3,PTPN6
4.053e-02	-3.21	FKBP_C	pfam domains	PF00254	15	1	17795	49	FKBP5
4.058e-02	-3.20	regulation of organelle organization	biological process	GO:0033043	1201	7	18204	49	HCK,PREX1,TMSB4X,ARAP1,AKAP13,ARHGEF18,SEPTIN9
4.073e-02	-3.20	PPAR signaling pathway	KEGG pathways	ko03320	72	2	7161	32	RXRA,ME1
4.073e-02	-3.20	Leishmaniasis	KEGG pathways	hsa05140	72	2	7161	32	ITGB2,PTPN6
4.073e-02	-3.20	PPAR signaling pathway	KEGG pathways	hsa03320	72	2	7161	32	RXRA,ME1
4.073e-02	-3.20	Leishmaniasis	KEGG pathways	ko05140	72	2	7161	32	ITGB2,PTPN6
4.076e-02	-3.20	EH	prosite domains	PS50031	11	1	12186	46	EHD4
4.085e-02	-3.20	Axon guidance	REACTOME pathways	R-HSA-422475	549	5	10285	36	PLXND1,ITGAV,DNM2,TLN1,GAB1
4.126e-02	-3.19	response to steroid hormone	biological process	GO:0048545	285	3	18204	49	DAB2,ZFP36L1,RXRA
4.150e-02	-3.18	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	gene3d domains	1.10.10.10	232	3	14470	48	SPI1,PREX1,ELF4
4.166e-02	-3.18	IFT74 (intraflagellar transport 74)	protein interactions	80173	126	2	19454	50	SEPTIN9,DISC1
4.166e-02	-3.18	GET3 (guided entry of tail-anchored proteins factor 3, ATPase)	protein interactions	439	126	2	19454	50	CCND2,DISC1
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GAB1,HEPHL1
4.193e-02	-3.17	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	10	16828	46	ME1,RBM47,RXRA,ITGAL,DAB2,CCND2,ELF4,TFEB,PTPN12,HCK
4.193e-02	-3.17	mucosal	COSMIC cancer mutations	mucosal	2009	10	16828	46	CCND2,ELF4,DAB2,HCK,TFEB,PTPN12,RBM47,ME1,RXRA,ITGAL
4.198e-02	-3.17	regulation of canonical NF-kappaB signal transduction	biological process	GO:0043122	287	3	18204	49	CD74,AKAP13,TMSB4X
4.207e-02	-3.17	negative regulation of immune effector process	biological process	GO:0002698	121	2	18204	49	SPI1,PTPN6
4.211e-02	-3.17	cell-cell junction	cellular component	GO:0005911	513	4	19108	49	ARHGAP24,PTPN6,TLN1,GAB1
4.223e-02	-3.16	regulation of adipose tissue development	biological process	GO:1904177	16	1	18204	49	SPI1
4.223e-02	-3.16	regulation of corticosteroid hormone secretion	biological process	GO:2000846	16	1	18204	49	DAB2
4.223e-02	-3.16	neutrophil homeostasis	biological process	GO:0001780	16	1	18204	49	SH2B3
4.223e-02	-3.16	regulation of Wnt signaling pathway, planar cell polarity pathway	biological process	GO:2000095	16	1	18204	49	DAB2
4.223e-02	-3.16	positive regulation of B cell differentiation	biological process	GO:0045579	16	1	18204	49	SPI1
4.223e-02	-3.16	branching involved in salivary gland morphogenesis	biological process	GO:0060445	16	1	18204	49	PLXND1
4.223e-02	-3.16	positive regulation of cyclin-dependent protein kinase activity	biological process	GO:1904031	16	1	18204	49	CCND2
4.223e-02	-3.16	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	49	RBPJ
4.223e-02	-3.16	regulation of ATP biosynthetic process	biological process	GO:2001169	16	1	18204	49	TMSB4X
4.234e-02	-3.16	positive regulation of innate immune response	biological process	GO:0045089	288	3	18204	49	HCK,RBM47,SPI1
4.248e-02	-3.16	sodium:proton antiporter activity	molecular function	GO:0015385	16	1	18094	49	SLC9A7
4.248e-02	-3.16	femur	COSMIC cancer mutations	femur	1197	7	16828	46	RBM47,STAB1,AKAP13,HEPHL1,ELF4,DAB2,PREX1
4.251e-02	-3.16	HSPA6 (heat shock protein family A (Hsp70) member 6)	protein interactions	3310	302	3	19454	50	TLN1,HCK,PTPN12
4.270e-02	-3.15	formation of primary germ layer	biological process	GO:0001704	122	2	18204	49	ITGAV,ITGB2
4.271e-02	-3.15	tissue development	biological process	GO:0009888	1757	9	18204	49	AKAP13,PLXND1,HCK,ITGB2,ITGAV,ARHGAP24,ZFP36L1,DAB2,RBPJ
4.273e-02	-3.15	MHC class II protein complex	cellular component	GO:0042613	17	1	19108	49	CD74
4.282e-02	-3.15	SLAMF6 (SLAM family member 6)	protein interactions	114836	17	1	19454	50	PTPN6
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	RBPJ
4.282e-02	-3.15	LY6D (lymphocyte antigen 6 family member D)	protein interactions	8581	17	1	19454	50	MCOLN2
4.282e-02	-3.15	CSH1 (chorionic somatomammotropin hormone 1)	protein interactions	1442	17	1	19454	50	PTPN12
4.282e-02	-3.15	ZNF557 (zinc finger protein 557)	protein interactions	79230	17	1	19454	50	ARHGAP24
4.282e-02	-3.15	ARPP19 (cAMP regulated phosphoprotein 19)	protein interactions	10776	17	1	19454	50	ME1
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	RBPJ
4.282e-02	-3.15	PLCE1 (phospholipase C epsilon 1)	protein interactions	51196	17	1	19454	50	FKBP5
4.282e-02	-3.15	STK32A (serine/threonine kinase 32A)	protein interactions	202374	17	1	19454	50	FKBP5
4.282e-02	-3.15	LRRC3 (leucine rich repeat containing 3)	protein interactions	81543	17	1	19454	50	SEPTIN9
4.282e-02	-3.15	OLFM1 (olfactomedin 1)	protein interactions	10439	17	1	19454	50	DISC1
4.282e-02	-3.15	Lrr1 (leucine rich repeat protein 1)	protein interactions	69706	17	1	19454	50	WDFY3
4.282e-02	-3.15	AOC1 (amine oxidase copper containing 1)	protein interactions	26	17	1	19454	50	DNM2
4.282e-02	-3.15	DNALI1 (dynein axonemal light intermediate chain 1)	protein interactions	7802	17	1	19454	50	DNM2
4.286e-02	-3.15	BTK (Bruton tyrosine kinase)	protein interactions	695	128	2	19454	50	HCK,GAB1
4.286e-02	-3.15	GAB2 (GRB2 associated binding protein 2)	protein interactions	9846	128	2	19454	50	PTPN6,GAB1
4.293e-02	-3.15	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	17	16828	46	CCND2,GAB1,ITGAV,PTPN12,MCOLN2,HCK,DNM2,ME1,ITM2B,HEPHL1,BTG1,AKAP13,CD74,PLXND1,WDFY3,DOCK2,ZFP36L1
4.311e-02	-3.14	human chr14q24.1	chromosome location	human chr14q24.1	23	1	26134	50	ZFP36L1
4.318e-02	-3.14	Cyclin_C	pfam domains	PF02984	16	1	17795	49	CCND2
4.340e-02	-3.14	Primary Focal Segmental Glomerulosclerosis FSGS	WikiPathways	WP2572	74	2	5310	24	ITGAV,TLN1
4.346e-02	-3.14	COL8A1 (collagen type VIII alpha 1 chain)	protein interactions	1295	129	2	19454	50	DISC1,BMP2K
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	RBPJ,FKBP5
4.397e-02	-3.12	cardiocyte differentiation	biological process	GO:0035051	124	2	18204	49	RBPJ,AKAP13
4.397e-02	-3.12	positive regulation of lipid metabolic process	biological process	GO:0045834	124	2	18204	49	CD74,DAB2
4.407e-02	-3.12	KIF3A (kinesin family member 3A)	protein interactions	11127	130	2	19454	50	HEPHL1,DISC1
4.415e-02	-3.12	establishment of localization	biological process	GO:0051234	3887	16	18204	49	DOCK2,MYO1F,CD68,CD74,MCOLN2,HEPHL1,DNM2,STAB1,ITGAV,DAB2,ITGAL,ZFP36L1,EHD4,SLC9A7,ITGB2,HCK
4.427e-02	-3.12	EIF3B (eukaryotic translation initiation factor 3 subunit B)	protein interactions	8662	307	3	19454	50	CCND2,ARHGAP24,CD74
4.433e-02	-3.12	Vitamin D Metabolism	WikiPathways	WP1531	10	1	5310	24	RXRA
4.433e-02	-3.12	Liver X Receptor Pathway	WikiPathways	WP2874	10	1	5310	24	RXRA
4.439e-02	-3.11	LINK_1	prosite domains	PS01241	12	1	12186	46	STAB1
4.451e-02	-3.11	bone-humerus-chondrosarcoma	COSMIC cancer mutations	bone-humerus-chondrosarcoma	123	2	16828	46	HEPHL1,ME1
4.459e-02	-3.11	Uptake and function of anthrax toxins	REACTOME pathways	R-HSA-5210891	13	1	10285	36	ANTXR2
4.459e-02	-3.11	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	36	RBPJ
4.459e-02	-3.11	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	36	RBPJ
4.459e-02	-3.11	FCGR activation	REACTOME pathways	R-HSA-2029481	13	1	10285	36	HCK
4.461e-02	-3.11	regulation of cell-matrix adhesion	biological process	GO:0001952	125	2	18204	49	DISC1,TLN1
4.468e-02	-3.11	LGALS7 (galectin 7)	protein interactions	3963	131	2	19454	50	DOCK8,GAB1
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	CD74
4.481e-02	-3.11	regulation of proton transport	biological process	GO:0010155	17	1	18204	49	TMSB4X
4.481e-02	-3.11	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological process	GO:1902165	17	1	18204	49	CD74
4.481e-02	-3.11	negative regulation of humoral immune response	biological process	GO:0002921	17	1	18204	49	PTPN6
4.481e-02	-3.11	regulation of plasma membrane organization	biological process	GO:1903729	17	1	18204	49	DNM2
4.481e-02	-3.11	response to hepatocyte growth factor	biological process	GO:0035728	17	1	18204	49	GAB1
4.481e-02	-3.11	specification of animal organ identity	biological process	GO:0010092	17	1	18204	49	RBPJ
4.481e-02	-3.11	regulation of lipoprotein metabolic process	biological process	GO:0050746	17	1	18204	49	ITGAV
4.493e-02	-3.10	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	3	18204	49	CD74,PTPN6,DAB2
4.493e-02	-3.10	Cyclin_C-dom	interpro domains	IPR004367	17	1	18521	50	CCND2
4.493e-02	-3.10	Thyroglobulin_1_sf	interpro domains	IPR036857	17	1	18521	50	CD74
4.493e-02	-3.10	Thyroglobulin_1	interpro domains	IPR000716	17	1	18521	50	CD74
4.494e-02	-3.10	human chr4p15.2	chromosome location	human chr4p15.2	24	1	26134	50	RBPJ
4.499e-02	-3.10	STK11 (serine/threonine kinase 11)	protein interactions	6794	309	3	19454	50	SEPTIN9,FKBP5,CCND2
4.507e-02	-3.10	oxidoreductase activity, acting on metal ions	molecular function	GO:0016722	17	1	18094	49	HEPHL1
4.507e-02	-3.10	low-density lipoprotein particle binding	molecular function	GO:0030169	17	1	18094	49	STAB1
4.507e-02	-3.10	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	49	PTPN6
4.507e-02	-3.10	transmembrane receptor protein tyrosine kinase adaptor activity	molecular function	GO:0005068	17	1	18094	49	SH2B3
4.507e-02	-3.10	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	49	PTPN6
4.515e-02	-3.10	skin-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma	493	4	16828	46	SH2B3,CCND2,BMP2K,ZFP36L1
4.519e-02	-3.10	filopodium membrane	cellular component	GO:0031527	18	1	19108	49	ITGAV
4.529e-02	-3.09	ZNF100 (zinc finger protein 100)	protein interactions	163227	18	1	19454	50	ARHGAP24
4.529e-02	-3.09	Chmp6 (charged multivesicular body protein 6)	protein interactions	208092	18	1	19454	50	PTPN6
4.529e-02	-3.09	ADO (2-aminoethanethiol dioxygenase)	protein interactions	84890	18	1	19454	50	DISC1
4.529e-02	-3.09	NAALADL2 (N-acetylated alpha-linked acidic dipeptidase like 2)	protein interactions	254827	18	1	19454	50	ITM2B
4.529e-02	-3.09	DCAF17 (DDB1 and CUL4 associated factor 17)	protein interactions	80067	18	1	19454	50	PREX1
4.529e-02	-3.09	TM4SF20 (transmembrane 4 L six family member 20)	protein interactions	79853	18	1	19454	50	CD74
4.529e-02	-3.09	ZNF365 (zinc finger protein 365)	protein interactions	22891	18	1	19454	50	DISC1
4.529e-02	-3.09	B3GAT2 (beta-1,3-glucuronyltransferase 2)	protein interactions	135152	18	1	19454	50	SEPTIN9
4.529e-02	-3.09	AK9 (adenylate kinase 9)	protein interactions	221264	18	1	19454	50	ARHGAP24
4.529e-02	-3.09	Numb (NUMB endocytic adaptor protein)	protein interactions	18222	18	1	19454	50	BMP2K
4.529e-02	-3.09	SRR (serine racemase)	protein interactions	63826	18	1	19454	50	DISC1
4.529e-02	-3.09	SPARCL1 (SPARC like 1)	protein interactions	8404	18	1	19454	50	DISC1
4.529e-02	-3.09	GALM (galactose mutarotase)	protein interactions	130589	18	1	19454	50	AKAP13
4.530e-02	-3.09	TXNDC12 (thioredoxin domain containing 12)	protein interactions	51060	132	2	19454	50	HCK,TLN1
4.530e-02	-3.09	TINF2 (TERF1 interacting nuclear factor 2)	protein interactions	26277	132	2	19454	50	ZFP36L1,FKBP5
4.531e-02	-3.09	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	40	16828	46	DOCK8,WDFY3,PLXND1,ELF4,HEPHL1,ITGAL,SH2B3,RGL1,ME1,PTPN12,MCOLN2,GAB1,CCND2,MYO1F,DOCK2,ZFP36L1,ARAP1,PTPN6,ANTXR2,RBM47,AKAP13,EHD4,CD74,RBPJ,ARHGEF18,FKBP5,DAB2,BTG1,ITM2B,ITGB2,DNM2,RXRA,TFEB,STAB1,HCK,ITGAV,TLN1,SLC9A7,PREX1,PTGIR
4.547e-02	-3.09	EH	smart domains	SM00027	11	1	9717	41	EHD4
4.547e-02	-3.09	Cupredoxins - blue copper proteins	gene3d domains	2.60.40.420	14	1	14470	48	HEPHL1
4.549e-02	-3.09	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	17	1	16828	46	SH2B3
4.549e-02	-3.09	chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	COSMIC cancer mutations	chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	17	1	16828	46	SH2B3
4.579e-02	-3.08	late endosome	cellular component	GO:0005770	312	3	19108	49	CD74,CD68,MCOLN2
4.581e-02	-3.08	Thyroglobulin_1	pfam domains	PF00086	17	1	17795	49	CD74
4.582e-02	-3.08	EZR (ezrin)	protein interactions	7430	526	4	19454	50	ARHGAP24,SEPTIN9,GAB1,PTPN12
4.590e-02	-3.08	regulation of myeloid leukocyte differentiation	biological process	GO:0002761	127	2	18204	49	CD74,ZFP36L1
4.591e-02	-3.08	PLAUR (plasminogen activator, urokinase receptor)	protein interactions	5329	133	2	19454	50	HCK,ITGB2
4.591e-02	-3.08	CBS (cystathionine beta-synthase)	protein interactions	875	133	2	19454	50	ARHGAP24,PREX1
4.591e-02	-3.08	DUT (deoxyuridine triphosphatase)	protein interactions	1854	133	2	19454	50	TLN1,FKBP5
4.615e-02	-3.08	skin-malignant_melanoma	COSMIC cancer mutations	skin-malignant_melanoma	15741	46	16828	46	BMP2K,CD68,ELF4,WDFY3,DOCK8,PLXND1,GAB1,MCOLN2,PTPN12,CCND2,SH2B3,RGL1,RBPJ,EHD4,BTG1,ZFP36L1,RBM47,ANTXR2,PTPN6,ITGAV,HCK,PTGIR,SLC9A7,TLN1,ITGB2,RXRA,HEPHL1,TMSB4X,SPI1,ITGAL,ME1,FKBP5,ARHGEF18,CD74,AKAP13,ARHGAP24,DAB2,ARAP1,MYO1F,DOCK2,DISC1,STAB1,TFEB,PREX1,ITM2B,DNM2
4.641e-02	-3.07	negative regulation of multicellular organismal process	biological process	GO:0051241	1237	7	18204	49	RBPJ,SH2B3,STAB1,PTPN6,SPI1,ELF4,CD74
4.655e-02	-3.07	regulation of protein binding	biological process	GO:0043393	128	2	18204	49	DAB2,DISC1
4.657e-02	-3.07	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	35	16828	46	ARAP1,DOCK2,MYO1F,ANTXR2,EHD4,AKAP13,ARHGEF18,FKBP5,DAB2,BTG1,ARHGAP24,ITM2B,ITGB2,DNM2,RXRA,ITGAV,HCK,STAB1,TLN1,SLC9A7,PREX1,PTGIR,WDFY3,DOCK8,PLXND1,HEPHL1,ELF4,ITGAL,ME1,RGL1,SH2B3,GAB1,MCOLN2,PTPN12,CCND2
4.671e-02	-3.06	Chemokine signaling pathway	KEGG pathways	ko04062	182	3	7161	32	DOCK2,HCK,PREX1
4.671e-02	-3.06	Chemokine signaling pathway	KEGG pathways	hsa04062	182	3	7161	32	DOCK2,HCK,PREX1
4.714e-02	-3.05	leg	COSMIC cancer mutations	leg	969	6	16828	46	SLC9A7,HCK,STAB1,AKAP13,PTPN12,WDFY3
4.716e-02	-3.05	EML4 (EMAP like 4)	protein interactions	27436	135	2	19454	50	FKBP5,TFEB
4.716e-02	-3.05	JAK3 (Janus kinase 3)	protein interactions	3718	135	2	19454	50	FKBP5,PTPN6
4.716e-02	-3.05	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	50	DAB2,BMP2K
4.717e-02	-3.05	STAT1 (signal transducer and activator of transcription 1)	protein interactions	6772	315	3	19454	50	RXRA,ITGAV,ARHGAP24
4.717e-02	-3.05	FLT3 (fms related receptor tyrosine kinase 3)	protein interactions	2322	315	3	19454	50	PTPN6,HCK,PTPN12
4.738e-02	-3.05	copper ion transport	biological process	GO:0006825	18	1	18204	49	HEPHL1
4.738e-02	-3.05	negative regulation of platelet activation	biological process	GO:0010544	18	1	18204	49	SH2B3
4.738e-02	-3.05	retinoic acid receptor signaling pathway	biological process	GO:0048384	18	1	18204	49	RXRA
4.738e-02	-3.05	regulation of dopamine metabolic process	biological process	GO:0042053	18	1	18204	49	ITGB2
4.738e-02	-3.05	positive regulation of superoxide anion generation	biological process	GO:0032930	18	1	18204	49	ITGB2
4.738e-02	-3.05	clathrin coat assembly	biological process	GO:0048268	18	1	18204	49	DAB2
4.738e-02	-3.05	positive regulation of type 2 immune response	biological process	GO:0002830	18	1	18204	49	CD74
4.738e-02	-3.05	regulation of catecholamine metabolic process	biological process	GO:0042069	18	1	18204	49	ITGB2
4.738e-02	-3.05	regulation of humoral immune response mediated by circulating immunoglobulin	biological process	GO:0002923	18	1	18204	49	PTPN6
4.738e-02	-3.05	heart formation	biological process	GO:0060914	18	1	18204	49	RBPJ
4.752e-02	-3.05	PPIase_dom_sf	interpro domains	IPR046357	18	1	18521	50	FKBP5
4.752e-02	-3.05	EGF_dom	interpro domains	IPR024731	18	1	18521	50	STAB1
4.760e-02	-3.04	immune response-activating signaling pathway	biological process	GO:0002757	302	3	18204	49	PTPN6,FYB1,HCK
4.766e-02	-3.04	lipoprotein particle receptor activity	molecular function	GO:0030228	18	1	18094	49	STAB1
4.766e-02	-3.04	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	49	MCOLN2
4.766e-02	-3.04	clathrin adaptor activity	molecular function	GO:0035615	18	1	18094	49	DAB2
4.774e-02	-3.04	ZNF138 (zinc finger protein 138)	protein interactions	7697	19	1	19454	50	ARHGAP24
4.774e-02	-3.04	PDIK1L (PDLIM1 interacting kinase 1 like)	protein interactions	149420	19	1	19454	50	FKBP5
4.774e-02	-3.04	MAML3 (mastermind like transcriptional coactivator 3)	protein interactions	55534	19	1	19454	50	RBPJ
4.774e-02	-3.04	NHERF4 (NHERF family PDZ scaffold protein 4)	protein interactions	79849	19	1	19454	50	PTGIR
4.774e-02	-3.04	MCOLN1 (mucolipin TRP cation channel 1)	protein interactions	57192	19	1	19454	50	MCOLN2
4.774e-02	-3.04	CRYBB1 (crystallin beta B1)	protein interactions	1414	19	1	19454	50	DISC1
4.774e-02	-3.04	PEX2 (peroxisomal biogenesis factor 2)	protein interactions	5828	19	1	19454	50	PTPN6
4.774e-02	-3.04	ZNF197 (zinc finger protein 197)	protein interactions	10168	19	1	19454	50	DISC1
4.774e-02	-3.04	COL4A4 (collagen type IV alpha 4 chain)	protein interactions	1286	19	1	19454	50	ANTXR2
4.779e-02	-3.04	EMSY (EMSY transcriptional repressor, BRCA2 interacting)	protein interactions	56946	136	2	19454	50	ELF4,DISC1
4.779e-02	-3.04	ROCK2 (Rho associated coiled-coil containing protein kinase 2)	protein interactions	9475	136	2	19454	50	TLN1,AKAP13
4.779e-02	-3.04	NR2F2 (nuclear receptor subfamily 2 group F member 2)	protein interactions	7026	136	2	19454	50	PTGIR,RBPJ
4.786e-02	-3.04	negative regulation of T cell activation	biological process	GO:0050868	130	2	18204	49	PTPN6,CD74
4.793e-02	-3.04	Retrograde neurotrophin signalling	REACTOME pathways	R-HSA-177504	14	1	10285	36	DNM2
4.793e-02	-3.04	Regulation of pyruvate dehydrogenase (PDH) complex	REACTOME pathways	R-HSA-204174	14	1	10285	36	RXRA
4.793e-02	-3.04	Regulation of IFNG signaling	REACTOME pathways	R-HSA-877312	14	1	10285	36	PTPN6
4.795e-02	-3.04	thyroid-other-neoplasm	COSMIC cancer mutations	thyroid-other-neoplasm	7637	27	16828	46	STAB1,TFEB,ITGAV,TLN1,SLC9A7,PTGIR,PREX1,ITGB2,DNM2,RXRA,AKAP13,EHD4,ARHGEF18,FKBP5,DAB2,ZFP36L1,DOCK2,MYO1F,ARAP1,GAB1,ITGAL,RGL1,SH2B3,BMP2K,HEPHL1,DOCK8,PLXND1
4.800e-02	-3.04	G_SEPTIN	prosite domains	PS51719	13	1	12186	46	SEPTIN9
4.819e-02	-3.03	innate immune response	biological process	GO:0045087	741	5	18204	49	MCOLN2,CD74,PTPN6,TFEB,HCK
4.835e-02	-3.03	coated vesicle	cellular component	GO:0030135	319	3	19108	49	DAB2,CD74,DNM2
4.837e-02	-3.03	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	45	16828	46	SH2B3,RGL1,CCND2,PTPN12,MCOLN2,GAB1,PLXND1,DOCK8,WDFY3,ELF4,BMP2K,CD68,RXRA,ITGB2,PTGIR,TLN1,SLC9A7,HCK,ITGAV,ANTXR2,RBM47,PTPN6,BTG1,RBPJ,EHD4,ME1,SPI1,ITGAL,TMSB4X,HEPHL1,DNM2,ITM2B,PREX1,TFEB,STAB1,DISC1,DOCK2,MYO1F,ARAP1,ARHGAP24,DAB2,CD74,FKBP5,ARHGEF18,AKAP13
4.838e-02	-3.03	heat shock protein binding	molecular function	GO:0031072	130	2	18094	49	FKBP5,ITGB2
4.844e-02	-3.03	EGF_3	pfam domains	PF12947	18	1	17795	49	STAB1
4.846e-02	-3.03	L1CAM interactions	REACTOME pathways	R-HSA-373760	101	2	10285	36	DNM2,ITGAV
4.852e-02	-3.03	mesoderm development	biological process	GO:0007498	131	2	18204	49	HCK,ZFP36L1
4.879e-02	-3.02	transport	biological process	GO:0006810	3615	15	18204	49	DNM2,HEPHL1,CD74,MCOLN2,MYO1F,DOCK2,ITGB2,HCK,SLC9A7,EHD4,DAB2,ITGAL,ZFP36L1,ITGAV,STAB1
4.881e-02	-3.02	EPO Signaling Pathway	SMPDB pathways	SMP0069678	17	1	1369	4	PTPN6
4.883e-02	-3.02	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	36	16828	46	ARAP1,DOCK2,MYO1F,ANTXR2,PTPN6,ARHGEF18,FKBP5,CD74,AKAP13,EHD4,ARHGAP24,DAB2,RXRA,DNM2,ITGAV,HCK,STAB1,PREX1,SLC9A7,TLN1,DOCK8,WDFY3,PLXND1,BMP2K,CD68,HEPHL1,ELF4,SPI1,ITGAL,ME1,RGL1,SH2B3,GAB1,PTPN12,MCOLN2,CCND2
4.884e-02	-3.02	clathrin-coated vesicle membrane	cellular component	GO:0030665	138	2	19108	49	CD74,DAB2
4.905e-02	-3.01	OR2A4 (olfactory receptor family 2 subfamily A member 4)	protein interactions	79541	138	2	19454	50	ME1,HEPHL1
4.905e-02	-3.01	FUT8 (fucosyltransferase 8)	protein interactions	2530	138	2	19454	50	MCOLN2,ITGAV
4.905e-02	-3.01	TENT5C (terminal nucleotidyltransferase 5C)	protein interactions	54855	138	2	19454	50	EHD4,SEPTIN9
4.916e-02	-3.01	defense response to bacterium	biological process	GO:0042742	306	3	18204	49	TFEB,STAB1,RBPJ
4.918e-02	-3.01	regulation of mRNA processing	biological process	GO:0050684	132	2	18204	49	ZFP36L1,RBM47
4.918e-02	-3.01	positive regulation of proteolysis involved in protein catabolic process	biological process	GO:1903052	132	2	18204	49	DAB2,DISC1
4.943e-02	-3.01	BAP1 (BRCA1 associated protein 1)	protein interactions	8314	1313	7	19454	50	DNM2,TLN1,SEPTIN9,ELF4,FKBP5,ZFP36L1,ME1
4.943e-02	-3.01	regulation of phosphorylation	biological process	GO:0042325	994	6	18204	49	CD74,EHD4,PTPN6,CCND2,ITGB2,DAB2
4.968e-02	-3.00	NEFM (neurofilament medium chain)	protein interactions	4741	139	2	19454	50	PTPN12,DISC1
4.968e-02	-3.00	IFT20 (intraflagellar transport 20)	protein interactions	90410	139	2	19454	50	DISC1,PTPN12
4.968e-02	-3.00	NAA15 (N-alpha-acetyltransferase 15, NatA auxiliary subunit)	protein interactions	80155	139	2	19454	50	RBPJ,ARHGAP24
4.977e-02	-3.00	ITGB1 (integrin subunit beta 1)	protein interactions	3688	322	3	19454	50	RXRA,ITGAV,TLN1
4.985e-02	-3.00	positive regulation of endothelial cell migration	biological process	GO:0010595	133	2	18204	49	GAB1,TMSB4X
4.995e-02	-3.00	base conversion or substitution editing	biological process	GO:0016553	19	1	18204	49	RBM47
4.995e-02	-3.00	regulation of early endosome to late endosome transport	biological process	GO:2000641	19	1	18204	49	DAB2
4.995e-02	-3.00	detection of temperature stimulus involved in sensory perception of pain	biological process	GO:0050965	19	1	18204	49	DISC1
4.995e-02	-3.00	positive regulation of endothelial cell differentiation	biological process	GO:0045603	19	1	18204	49	BTG1
4.995e-02	-3.00	protein localization to cell-cell junction	biological process	GO:0150105	19	1	18204	49	ARHGEF18
4.995e-02	-3.00	regulation of cell proliferation involved in heart morphogenesis	biological process	GO:2000136	19	1	18204	49	RBPJ
4.995e-02	-3.00	adenylate cyclase-activating adrenergic receptor signaling pathway	biological process	GO:0071880	19	1	18204	49	AKAP13
4.995e-02	-3.00	regulation of mast cell activation	biological process	GO:0033003	19	1	18204	49	PTPN6
4.995e-02	-3.00	negative regulation of amyloid precursor protein biosynthetic process	biological process	GO:0042985	19	1	18204	49	ITM2B
4.995e-02	-3.00	3'-UTR-mediated mRNA destabilization	biological process	GO:0061158	19	1	18204	49	ZFP36L1
4.995e-02	-3.00	regulation of B cell apoptotic process	biological process	GO:0002902	19	1	18204	49	CD74