TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols WP306 Focal Adhesion 0.00017569850221641 -8.64674108747227 195 6 0.25 24 5310 3685,7094,3055,3689,894,3683 ITGAV,TLN1,HCK,ITGB2,CCND2,ITGAL WP185 Integrin-mediated Cell Adhesion 0.00105251134178218 -6.85657621642572 103 4 0.166666666666667 24 5310 7094,3683,3685,3689 TLN1,ITGAL,ITGAV,ITGB2 WP2879 Farnesoid X Receptor Pathway 0.00319472468334929 -5.74625436596126 19 2 0.0833333333333333 24 5310 2289,6256 FKBP5,RXRA WP364 IL-6 signaling pathway 0.0157927773666919 -4.14820257215477 43 2 0.0833333333333333 24 5310 3055,2549 HCK,GAB1 WP286 IL-3 Signaling Pathway 0.0202318263447576 -3.90049835284834 49 2 0.0833333333333333 24 5310 5777,3055 PTPN6,HCK WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 0.0434005254088218 -3.13728373175501 74 2 0.0833333333333333 24 5310 3685,7094 ITGAV,TLN1 WP2874 Liver X Receptor Pathway 0.044326272924019 -3.11617770946425 10 1 0.0416666666666667 24 5310 6256 RXRA WP1531 Vitamin D Metabolism 0.044326272924019 -3.11617770946425 10 1 0.0416666666666667 24 5310 6256 RXRA WP2007 Iron metabolism in placenta 0.0529626476030068 -2.93816837609906 12 1 0.0416666666666667 24 5310 341208 HEPHL1 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness 0.0529626476030068 -2.93816837609906 12 1 0.0416666666666667 24 5310 3685 ITGAV WP2261 Signaling Pathways in Glioblastoma 0.0533578300231828 -2.93073454493364 83 2 0.0833333333333333 24 5310 894,2549 CCND2,GAB1 WP3892 Development of pulmonary dendritic cells and macrophage subsets 0.057252737534196 -2.8602798204998 13 1 0.0416666666666667 24 5310 6688 SPI1 WP1434 Osteopontin Signaling 0.057252737534196 -2.8602798204998 13 1 0.0416666666666667 24 5310 3685 ITGAV WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation 0.057252737534196 -2.8602798204998 13 1 0.0416666666666667 24 5310 894 CCND2 WP322 Osteoblast Signaling 0.0615241995502924 -2.78832469294337 14 1 0.0416666666666667 24 5310 3685 ITGAV WP69 T-Cell antigen Receptor (TCR) Signaling Pathway 0.0628285180369725 -2.76734619971522 91 2 0.0833333333333333 24 5310 2533,10019 FYB1,SH2B3 WP23 B Cell Receptor Signaling Pathway 0.0715536340842787 -2.63730798343401 98 2 0.0833333333333333 24 5310 2549,5777 GAB1,PTPN6 WP1992 TarBasePathway 0.0826047885448695 -2.49368762743738 19 1 0.0416666666666667 24 5310 7114 TMSB4X WP247 Small Ligand GPCRs 0.0826047885448695 -2.49368762743738 19 1 0.0416666666666667 24 5310 5739 PTGIR WP3599 Transcription factor regulation in adipogenesis 0.095034512383528 -2.35351516510713 22 1 0.0416666666666667 24 5310 6256 RXRA WP2878 PPAR Alpha Pathway 0.111356628422845 -2.19501735922968 26 1 0.0416666666666667 24 5310 6256 RXRA WP3845 Canonical and Non-canonical Notch signaling 0.115392858725284 -2.15941280961946 27 1 0.0416666666666667 24 5310 3516 RBPJ WP2583 T-Cell Receptor and Co-stimulatory Signaling 0.12341267628094 -2.09222144765754 29 1 0.0416666666666667 24 5310 5777 PTPN6 WP2643 Nanoparticle-mediated activation of receptor signaling 0.12341267628094 -2.09222144765754 29 1 0.0416666666666667 24 5310 7094 TLN1 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 0.127396409621839 -2.06045171817338 30 1 0.0416666666666667 24 5310 7942 TFEB WP98 Prostaglandin Synthesis and Regulation 0.127396409621839 -2.06045171817338 30 1 0.0416666666666667 24 5310 5739 PTGIR WP34 Ovarian Infertility Genes 0.135311888469417 -2.00017288019015 32 1 0.0416666666666667 24 5310 894 CCND2 WP2875 Constitutive Androstane Receptor Pathway 0.135311888469417 -2.00017288019015 32 1 0.0416666666666667 24 5310 6256 RXRA WP2884 NRF2 pathway 0.135406885295831 -1.99947106827669 143 2 0.0833333333333333 24 5310 4199,6256 ME1,RXRA WP3676 BDNF-TrkB Signaling 0.139243778328393 -1.97152908104083 33 1 0.0416666666666667 24 5310 2549 GAB1 WP2197 Endothelin Pathways 0.139243778328393 -1.97152908104083 33 1 0.0416666666666667 24 5310 5739 PTGIR WP313 Signaling of Hepatocyte Growth Factor Receptor 0.143158530901031 -1.94380265507444 34 1 0.0416666666666667 24 5310 2549 GAB1 WP244 Alpha 6 Beta 4 signaling pathway 0.147056217643742 -1.91694033236162 35 1 0.0416666666666667 24 5310 2549 GAB1 WP619 Type II interferon signaling (IFNG) 0.154800678063188 -1.86561693758295 37 1 0.0416666666666667 24 5310 6688 SPI1 WP170 Nuclear Receptors 0.162477725592227 -1.81721435988635 39 1 0.0416666666666667 24 5310 6256 RXRA WP437 EGF/EGFR Signaling Pathway 0.165321124858611 -1.79986548523272 162 2 0.0833333333333333 24 5310 2549,5782 GAB1,PTPN12 WP49 IL-2 Signaling Pathway 0.173868124787401 -1.74945817064237 42 1 0.0416666666666667 24 5310 894 CCND2 WP716 Vitamin A and Carotenoid Metabolism 0.181379086917255 -1.70716603506264 44 1 0.0416666666666667 24 5310 6256 RXRA WP268 Notch Signaling Pathway 0.188824581964584 -1.66693683266256 46 1 0.0416666666666667 24 5310 3516 RBPJ WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 0.192522950132158 -1.64753991089486 47 1 0.0416666666666667 24 5310 3055 HCK WP2849 Hematopoietic Stem Cell Differentiation 0.196205155944874 -1.6285944531703 48 1 0.0416666666666667 24 5310 6688 SPI1 WP410 Diurnally Regulated Genes with Circadian Orthologs 0.199871266979575 -1.61008178477754 49 1 0.0416666666666667 24 5310 694 BTG1 WP2267 Synaptic Vesicle Pathway 0.210773703089228 -1.5569702182502 52 1 0.0416666666666667 24 5310 1785 DNM2 WP673 ErbB Signaling Pathway 0.217962746688231 -1.52343111754709 54 1 0.0416666666666667 24 5310 2549 GAB1 WP585 Interferon type I signaling pathways 0.221533693049855 -1.50718058797308 55 1 0.0416666666666667 24 5310 5777 PTPN6 WP395 IL-4 Signaling Pathway 0.221533693049855 -1.50718058797308 55 1 0.0416666666666667 24 5310 5777 PTPN6 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway 0.221533693049855 -1.50718058797308 55 1 0.0416666666666667 24 5310 6688 SPI1 WP304 Kit receptor signaling pathway 0.239155290912422 -1.43064218527693 60 1 0.0416666666666667 24 5310 5777 PTPN6 WP3584 MECP2 and Associated Rett Syndrome 0.246096344896291 -1.40203217380314 62 1 0.0416666666666667 24 5310 2289 FKBP5 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 0.246096344896291 -1.40203217380314 62 1 0.0416666666666667 24 5310 5777 PTPN6 WP61 Notch Signaling Pathway 0.246096344896291 -1.40203217380314 62 1 0.0416666666666667 24 5310 3516 RBPJ WP45 G1 to S cell cycle control 0.266557294792735 -1.32216606864184 68 1 0.0416666666666667 24 5310 894 CCND2 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways 0.266557294792735 -1.32216606864184 68 1 0.0416666666666667 24 5310 7114 TMSB4X WP707 DNA Damage Response 0.269915292676347 -1.30964710003592 69 1 0.0416666666666667 24 5310 894 CCND2 WP428 Wnt Signaling Pathway 0.27325855407033 -1.29733684749204 70 1 0.0416666666666667 24 5310 894 CCND2 WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy 0.293012103583734 -1.22754136165877 76 1 0.0416666666666667 24 5310 3685 ITGAV WP2037 Prolactin Signaling Pathway 0.293012103583734 -1.22754136165877 76 1 0.0416666666666667 24 5310 5777 PTPN6 WP1530 miRNA Regulation of DNA Damage Response 0.346225509788052 -1.06066495383606 93 1 0.0416666666666667 24 5310 894 CCND2 WP35 G Protein Signaling Pathways 0.352227424247542 -1.04347822039903 95 1 0.0416666666666667 24 5310 11214 AKAP13 WP2064 Neural Crest Differentiation 0.372821043505954 -0.986656750591158 102 1 0.0416666666666667 24 5310 3516 RBPJ WP179 Cell Cycle 0.381453474761199 -0.963766389138328 105 1 0.0416666666666667 24 5310 894 CCND2 WP399 Wnt Signaling Pathway and Pluripotency 0.384305562488031 -0.956317307178253 106 1 0.0416666666666667 24 5310 894 CCND2 WP710 DNA Damage Response (only ATM dependent) 0.406672923367749 -0.899746044710767 114 1 0.0416666666666667 24 5310 894 CCND2 WP236 Adipogenesis 0.451646446271371 -0.794855603741448 131 1 0.0416666666666667 24 5310 6256 RXRA WP3915 Angiopoietin Like Protein 8 Regulatory Pathway 0.454187571063514 -0.789245014142349 132 1 0.0416666666666667 24 5310 6256 RXRA WP366 TGF-beta Signaling Pathway 0.45671740851049 -0.783690441474107 133 1 0.0416666666666667 24 5310 1601 DAB2 WP2853 Endoderm Differentiation 0.486212311410723 -0.721109895720326 145 1 0.0416666666666667 24 5310 1601 DAB2 WP1449 Regulation of toll-like receptor signaling pathway 0.486212311410723 -0.721109895720326 145 1 0.0416666666666667 24 5310 5777 PTPN6 WP51 Regulation of Actin Cytoskeleton 0.495698280183108 -0.701787843432863 149 1 0.0416666666666667 24 5310 7114 TMSB4X WP481 Insulin Signaling 0.523159710628937 -0.647868487482874 161 1 0.0416666666666667 24 5310 2549 GAB1 WP2377 Integrated Pancreatic Cancer Pathway 0.597210486453478 -0.515485654105094 197 1 0.0416666666666667 24 5310 6256 RXRA WP455 GPCRs, Class A Rhodopsin-like 0.699650216660309 -0.357174759310901 259 1 0.0416666666666667 24 5310 5739 PTGIR WP186 Homologous recombination 0.999999999984192 -1.58084500493519e-11 13 0 0 24 5310 WP3871 Valproic acid pathway 0.999999999984192 -1.58084500493519e-11 13 0 0 24 5310 WP1423 Ganglio Sphingolipid Metabolism 0.999999999984192 -1.58084500493519e-11 13 0 0 24 5310 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation 0.999999999984192 -1.58084500493519e-11 13 0 0 24 5310 WP2881 Estrogen Receptor Pathway 0.999999999984192 -1.58084500493519e-11 13 0 0 24 5310 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling 0.999999999984192 -1.58084500493519e-11 13 0 0 24 5310 WP2526 PDGF Pathway 0.999999999984381 -1.5618591369391e-11 38 0 0 24 5310 WP383 Striated Muscle Contraction 0.999999999984381 -1.5618591369391e-11 38 0 0 24 5310 WP2029 Cell Differentiation - Index 0.999999999984381 -1.5618591369391e-11 38 0 0 24 5310 WP2447 Amyotrophic lateral sclerosis (ALS) 0.999999999984381 -1.5618591369391e-11 38 0 0 24 5310 WP237 Glucocorticoid & Mineralcorticoid Metabolism 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP2485 NAD Biosynthesis II (from tryptophan) 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP3634 Insulin signalling in human adipocytes (normal condition) 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP3635 Insulin signalling in human adipocytes (diabetic condition) 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP1604 Codeine and Morphine Metabolism 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP136 Phase I biotransformations, non P450 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP2338 miRNA Biogenesis 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP3655 Hypothetical Craniofacial Development Pathway 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP3407 FTO Obesity Variant Mechanism 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP2276 Glial Cell Differentiation 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP1589 Folate-Alcohol and Cancer Pathway 0.999999999987897 -1.21027654213477e-11 8 0 0 24 5310 WP2359 Parkin-Ubiquitin Proteasomal System pathway 0.999999999988077 -1.19232227181961e-11 70 0 0 24 5310 WP2272 Pathogenic Escherichia coli infection 0.999999999988831 -1.11691074422095e-11 55 0 0 24 5310 WP2942 DDX1 as a regulatory component of the Drosha microprocessor 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP3585 Cytosine methylation 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP561 Heme Biosynthesis 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP288 NLR Proteins 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP3297 EV release from cardiac cells and their functional effects 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP3674 Tgif disruption of Shh signaling 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP696 Benzo(a)pyrene metabolism 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP531 Mismatch repair 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP3593 miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP3300 Dual hijack model of Vif in HIV infection 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP3875 ATR Signaling 0.999999999990645 -9.35535327728595e-12 9 0 0 24 5310 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway 0.99999999999082 -9.18041126408202e-12 27 0 0 24 5310 WP500 Glycogen Metabolism 0.99999999999095 -9.04997076514868e-12 36 0 0 24 5310 WP2012 miRs in Muscle Cell Differentiation 0.99999999999095 -9.04997076514868e-12 36 0 0 24 5310 WP3298 Melatonin metabolism and effects 0.99999999999095 -9.04997076514868e-12 36 0 0 24 5310 WP22 IL-9 Signaling Pathway 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP384 Apoptosis Modulation by HSP70 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP404 Nucleotide Metabolism 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP3287 Overview of nanoparticle effects 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP697 Estrogen metabolism 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling 0.999999999990991 -9.00898132512817e-12 19 0 0 24 5310 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 0.999999999990996 -9.00419262457573e-12 44 0 0 24 5310 WP2332 Interleukin-11 Signaling Pathway 0.999999999990996 -9.00419262457573e-12 44 0 0 24 5310 WP2369 Histone Modifications 0.999999999991927 -8.07310239530797e-12 69 0 0 24 5310 WP176 Folate Metabolism 0.999999999991927 -8.07310239530797e-12 69 0 0 24 5310 WP2059 Alzheimers Disease 0.999999999992062 -7.93788533929017e-12 148 0 0 24 5310 WP1533 Vitamin B12 Metabolism 0.999999999992283 -7.71658687237922e-12 53 0 0 24 5310 WP2406 Cardiac Progenitor Differentiation 0.999999999992283 -7.71658687237922e-12 53 0 0 24 5310 WP107 Translation Factors 0.999999999992283 -7.71658687237922e-12 53 0 0 24 5310 WP363 Wnt Signaling Pathway Netpath 0.999999999992283 -7.71658687237922e-12 53 0 0 24 5310 WP2857 Mesodermal Commitment Pathway 0.999999999992474 -7.52637108988163e-12 155 0 0 24 5310 WP2637 Structural Pathway of Interleukin 1 (IL-1) 0.999999999993034 -6.96558740686921e-12 50 0 0 24 5310 WP1545 miRNAs involved in DNA damage response 0.999999999993034 -6.96558740686921e-12 50 0 0 24 5310 WP2034 Leptin signaling pathway 0.999999999993162 -6.83765923206817e-12 76 0 0 24 5310 WP3527 Preimplantation Embryo 0.999999999994694 -5.30631216669416e-12 60 0 0 24 5310 WP558 Complement and Coagulation Cascades 0.999999999994694 -5.30631216669416e-12 60 0 0 24 5310 WP3624 Lung fibrosis 0.999999999994719 -5.28082380883954e-12 63 0 0 24 5310 WP43 Oxidation by Cytochrome P450 0.999999999994719 -5.28082380883954e-12 63 0 0 24 5310 WP2509 Nanoparticle triggered autophagic cell death 0.99999999999508 -4.92011437779749e-12 24 0 0 24 5310 WP262 EBV LMP1 signaling 0.99999999999508 -4.92011437779749e-12 24 0 0 24 5310 WP334 GPCRs, Class B Secretin-like 0.99999999999508 -4.92011437779749e-12 24 0 0 24 5310 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia 0.99999999999508 -4.92011437779749e-12 24 0 0 24 5310 WP1539 Angiogenesis 0.99999999999508 -4.92011437779749e-12 24 0 0 24 5310 WP254 Apoptosis 0.999999999995796 -4.20443799780294e-12 86 0 0 24 5310 WP188 Focal Adhesion 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP2536 Colchicine Metabolic Pathway 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP661 Glucose Homeostasis 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP3191 TSLP Signaling Pathway 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP1 Statin Pathway 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP3627 Gut-Liver Indole Metabolism 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP108 Selenium metabolism/Selenoproteins 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP2190 One carbon donor 0.999999999995899 -4.10070762069115e-12 1 0 0 24 5310 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer 0.999999999996499 -3.50078003908047e-12 5 0 0 24 5310 WP311 Synthesis and Degradation of Ketone Bodies 0.999999999996499 -3.50078003908047e-12 5 0 0 24 5310 WP2597 Secretion of Hydrochloric Acid in Parietal Cells 0.999999999996499 -3.50078003908047e-12 5 0 0 24 5310 WP2542 Sulindac Metabolic Pathway 0.999999999996499 -3.50078003908047e-12 5 0 0 24 5310 WP688 Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs) 0.999999999996499 -3.50078003908047e-12 5 0 0 24 5310 WP3596 miR-517 relationship with ARCN1 and USP1 0.999999999996499 -3.50078003908047e-12 5 0 0 24 5310 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP167 Eicosanoid Synthesis 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP1584 Type II diabetes mellitus 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP272 Blood Clotting Cascade 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP1424 Globo Sphingolipid Metabolism 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP3645 NAD+ biosynthetic pathways 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP545 Complement Activation 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP357 Fatty Acid Biosynthesis 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP100 Glutathione metabolism 0.999999999996782 -3.21828494034471e-12 22 0 0 24 5310 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer 0.999999999997066 -2.93422610826283e-12 54 0 0 24 5310 WP3286 Copper homeostasis 0.999999999997066 -2.93422610826283e-12 54 0 0 24 5310 WP623 Oxidative phosphorylation 0.999999999997066 -2.93422610826283e-12 54 0 0 24 5310 WP3865 RIG-I-like Receptor Signaling 0.999999999997463 -2.53744309893695e-12 61 0 0 24 5310 WP497 Urea cycle and metabolism of amino groups 0.9999999999976 -2.40026565651343e-12 20 0 0 24 5310 WP391 Mitochondrial Gene Expression 0.9999999999976 -2.40026565651343e-12 20 0 0 24 5310 WP516 Hypertrophy Model 0.9999999999976 -2.40026565651343e-12 20 0 0 24 5310 WP1422 Sphingolipid Metabolism 0.9999999999976 -2.40026565651343e-12 20 0 0 24 5310 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling 0.9999999999976 -2.40026565651343e-12 20 0 0 24 5310 WP1742 TP53 Network 0.9999999999976 -2.40026565651343e-12 20 0 0 24 5310 WP325 Triacylglyceride Synthesis 0.999999999997706 -2.29391704713041e-12 26 0 0 24 5310 WP698 Glucuronidation 0.999999999997706 -2.29391704713041e-12 26 0 0 24 5310 WP530 Cytokines and Inflammatory Response 0.999999999997706 -2.29391704713041e-12 26 0 0 24 5310 WP26 Signal Transduction of S1P Receptor 0.999999999997706 -2.29391704713041e-12 26 0 0 24 5310 WP581 EPO Receptor Signaling 0.999999999997706 -2.29391704713041e-12 26 0 0 24 5310 WP2855 Dopaminergic Neurogenesis 0.999999999997814 -2.18573196874482e-12 30 0 0 24 5310 WP241 One Carbon Metabolism 0.999999999997814 -2.18573196874482e-12 30 0 0 24 5310 WP2870 Extracellular vesicle-mediated signaling in recipient cells 0.999999999997814 -2.18573196874482e-12 30 0 0 24 5310 WP3851 TLR4 Signaling and Tolerance 0.999999999997814 -2.18573196874482e-12 30 0 0 24 5310 WP129 Matrix Metalloproteinases 0.999999999997814 -2.18573196874482e-12 30 0 0 24 5310 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity 0.99999999999786 -2.13947816469321e-12 35 0 0 24 5310 WP3617 Photodynamic therapy-induced NF-kB survival signaling 0.99999999999786 -2.13947816469321e-12 35 0 0 24 5310 WP3601 Composition of Lipid Particles 0.999999999997867 -2.13292916972887e-12 10 0 0 24 5310 WP2113 Type III interferon signaling 0.999999999997867 -2.13292916972887e-12 10 0 0 24 5310 WP496 Steroid Biosynthesis 0.999999999997867 -2.13292916972887e-12 10 0 0 24 5310 WP3656 Interleukin-1 Induced Activation of NF-kappa-B 0.999999999997867 -2.13292916972887e-12 10 0 0 24 5310 WP2333 Trans-sulfuration pathway 0.999999999997867 -2.13292916972887e-12 10 0 0 24 5310 WP704 Methylation Pathways 0.999999999997867 -2.13292916972887e-12 10 0 0 24 5310 WP474 Endochondral Ossification 0.999999999997956 -2.04421679111356e-12 65 0 0 24 5310 WP117 GPCRs, Other 0.999999999997999 -2.00094474729858e-12 95 0 0 24 5310 WP2361 Gastric Cancer Network 1 0.999999999998026 -1.97399673628837e-12 28 0 0 24 5310 WP2249 Metastatic brain tumor 0.999999999998026 -1.97399673628837e-12 28 0 0 24 5310 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 0.999999999998132 -1.86779359572902e-12 17 0 0 24 5310 WP78 TCA Cycle 0.999999999998132 -1.86779359572902e-12 17 0 0 24 5310 WP2916 Interactome of polycomb repressive complex 2 (PRC2) 0.999999999998132 -1.86779359572902e-12 17 0 0 24 5310 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation 0.999999999998132 -1.86779359572902e-12 17 0 0 24 5310 WP2289 Drug Induction of Bile Acid Pathway 0.999999999998132 -1.86779359572902e-12 17 0 0 24 5310 WP3874 Canonical and Non-Canonical TGF-B signaling 0.999999999998132 -1.86779359572902e-12 17 0 0 24 5310 WP554 ACE Inhibitor Pathway 0.999999999998132 -1.86779359572902e-12 17 0 0 24 5310 WP2371 Parkinsons Disease Pathway 0.999999999998313 -1.68719206861684e-12 83 0 0 24 5310 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 0.999999999998313 -1.6867529568996e-12 42 0 0 24 5310 WP466 DNA Replication 0.999999999998313 -1.6867529568996e-12 42 0 0 24 5310 WP2636 Common Pathways Underlying Drug Addiction 0.999999999998313 -1.6867529568996e-12 42 0 0 24 5310 WP405 Eukaryotic Transcription Initiation 0.999999999998313 -1.6867529568996e-12 42 0 0 24 5310 WP477 Cytoplasmic Ribosomal Proteins 0.999999999998352 -1.64764616780996e-12 90 0 0 24 5310 WP138 Androgen receptor signaling pathway 0.999999999998352 -1.64764616780996e-12 90 0 0 24 5310 WP1772 Apoptosis Modulation and Signaling 0.999999999998385 -1.61469808496486e-12 94 0 0 24 5310 WP231 TNF alpha Signaling Pathway 0.999999999998385 -1.61469808496486e-12 94 0 0 24 5310 WP382 MAPK Signaling Pathway 0.999999999998429 -1.5714175418864e-12 170 0 0 24 5310 WP2828 Bladder Cancer 0.99999999999912 -8.7967345518201e-13 32 0 0 24 5310 WP3858 Toll-like Receptor Signaling 0.99999999999912 -8.7967345518201e-13 32 0 0 24 5310 WP2525 Trans-sulfuration and one carbon metabolism 0.99999999999912 -8.7967345518201e-13 32 0 0 24 5310 WP3893 Development and heterogeneity of the ILC family 0.99999999999912 -8.7967345518201e-13 32 0 0 24 5310 WP727 Monoamine Transport 0.99999999999912 -8.7967345518201e-13 32 0 0 24 5310 WP2355 Corticotropin-releasing hormone signaling pathway 0.999999999999203 -7.96825883981295e-13 93 0 0 24 5310 WP143 Fatty Acid Beta Oxidation 0.999999999999335 -6.65106261738394e-13 34 0 0 24 5310 WP1601 Fluoropyrimidine Activity 0.999999999999335 -6.65106261738394e-13 34 0 0 24 5310 WP400 p38 MAPK Signaling Pathway 0.999999999999335 -6.65106261738394e-13 34 0 0 24 5310 WP1528 Physiological and Pathological Hypertrophy of the Heart 0.999999999999782 -2.18265777579136e-13 25 0 0 24 5310 WP2865 IL1 and megakaryocytes in obesity 0.999999999999782 -2.18265777579136e-13 25 0 0 24 5310 WP2895 Differentiation of white and brown adipocyte 0.999999999999782 -2.18265777579136e-13 25 0 0 24 5310 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease 0.999999999999782 -2.18265777579136e-13 25 0 0 24 5310 WP205 IL-7 Signaling Pathway 0.999999999999782 -2.18265777579136e-13 25 0 0 24 5310 WP2795 Cardiac Hypertrophic Response 0.999999999999881 -1.18947340587641e-13 57 0 0 24 5310 WP195 IL-1 signaling pathway 0.999999999999881 -1.18947340587641e-13 57 0 0 24 5310 WP2805 RNA interference 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP1272 Selenium Micronutrient Network 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP1995 Effects of Nitric Oxide 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP2596 Gastric acid production 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP3924 Hfe effect on hepcidin production 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP3595 mir-124 predicted interactions with cell cycle and differentiation 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP699 Aflatoxin B1 metabolism 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP528 Acetylcholine Synthesis 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP134 Pentose Phosphate Pathway 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP438 Non-homologous end joining 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP1310 Selenium Micronutrient Network 0.999999999999998 -2.07964530348555e-15 7 0 0 24 5310 WP422 MAPK Cascade 1.00000000000003 2.70556542515841e-14 29 0 0 24 5310 WP3613 Photodynamic therapy-induced unfolded protein response 1.00000000000003 2.70556542515841e-14 29 0 0 24 5310 WP2328 Allograft Rejection 1.0000000000001 1.03927594460405e-13 80 0 0 24 5310 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway 1.0000000000003 2.96843203953287e-13 41 0 0 24 5310 WP560 TGF-beta Receptor Signaling 1.00000000000033 3.25507846463829e-13 58 0 0 24 5310 WP183 Proteasome Degradation 1.00000000000046 4.61824057273141e-13 66 0 0 24 5310 WP3651 Pathways Affected in Adenoid Cystic Carcinoma 1.00000000000046 4.61824057273141e-13 66 0 0 24 5310 WP2374 Oncostatin M Signaling Pathway 1.00000000000046 4.61824057273141e-13 66 0 0 24 5310 WP2324 AGE/RAGE pathway 1.00000000000046 4.61824057273141e-13 66 0 0 24 5310 WP3611 Photodynamic therapy-induced AP-1 survival signaling. 1.00000000000111 1.10718233812629e-12 51 0 0 24 5310 WP3646 Hepatitis C and Hepatocellular Carcinoma 1.00000000000111 1.10718233812629e-12 51 0 0 24 5310 WP2846 Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation 1.00000000000133 1.32950803293485e-12 3 0 0 24 5310 WP3408 Evolocumab Mechanism 1.00000000000133 1.32950803293485e-12 3 0 0 24 5310 WP2848 Differentiation Pathway 1.00000000000141 1.40561119754597e-12 48 0 0 24 5310 WP2586 Aryl Hydrocarbon Receptor 1.00000000000141 1.40561119754597e-12 48 0 0 24 5310 WP2873 Aryl Hydrocarbon Receptor Pathway 1.00000000000141 1.40561119754597e-12 48 0 0 24 5310 WP2516 ATM Signaling Pathway 1.00000000000176 1.75823009958741e-12 40 0 0 24 5310 WP524 G13 Signaling Pathway 1.00000000000176 1.75823009958741e-12 40 0 0 24 5310 WP127 IL-5 Signaling Pathway 1.00000000000176 1.75823009958741e-12 40 0 0 24 5310 WP1981 Thyroxine (Thyroid Hormone) Production 1.00000000000184 1.84048463055294e-12 6 0 0 24 5310 WP694 Arylamine metabolism 1.00000000000184 1.84048463055294e-12 6 0 0 24 5310 WP3891 Benzene metabolism 1.00000000000184 1.84048463055294e-12 6 0 0 24 5310 WP1600 Nicotine Metabolism 1.00000000000184 1.84048463055294e-12 6 0 0 24 5310 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP53 ID signaling pathway 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP12 Osteoclast Signaling 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP501 GPCRs, Class C Metabotropic glutamate, pheromone 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP47 Hedgehog Signaling Pathway 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP3644 NAD+ metabolism 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP550 Biogenic Amine Synthesis 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP1946 Cori Cycle 1.00000000000194 1.93513140507834e-12 16 0 0 24 5310 WP2435 Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis 1.00000000000196 1.95715085567205e-12 15 0 0 24 5310 WP3 Transcriptional activation by NRF2 1.00000000000196 1.95715085567205e-12 15 0 0 24 5310 WP197 Cholesterol Biosynthesis 1.00000000000196 1.95715085567205e-12 15 0 0 24 5310 WP206 Fatty Acid Omega Oxidation 1.00000000000196 1.95715085567205e-12 15 0 0 24 5310 WP2858 Ectoderm Differentiation 1.00000000000204 2.03502652450735e-12 143 0 0 24 5310 WP24 Peptide GPCRs 1.00000000000216 2.15640133716008e-12 74 0 0 24 5310 WP534 Glycolysis and Gluconeogenesis 1.00000000000221 2.20889337407563e-12 49 0 0 24 5310 WP2491 Diclofenac Metabolic Pathway 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP690 Polyol Pathway 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP2253 Pilocytic astrocytoma 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP897 Androgen receptor signaling pathway 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP1941 Peroxisomal beta-oxidation of tetracosanoyl-CoA 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP1133 Androgen receptor signaling pathway 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP3302 eIF5A regulation in response to inhibition of the nuclear export system 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP521 Amino acid conjugation of benzoic acid 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP1603 Nicotine Activity on Chromaffin Cells 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP3633 Caffeine and Theobromine metabolism 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP2889 Oxytocin signaling 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP733 Serotonin Receptor 2 and STAT3 Signaling 1.00000000000224 2.24435928970918e-12 4 0 0 24 5310 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression 1.00000000000226 2.25808625830976e-12 18 0 0 24 5310 WP3413 NOTCH1 regulation of human endothelial cell calcification 1.00000000000226 2.25808625830976e-12 18 0 0 24 5310 WP692 Sulfation Biotransformation Reaction 1.00000000000226 2.25808625830976e-12 18 0 0 24 5310 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds 1.00000000000226 2.25808625830976e-12 18 0 0 24 5310 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition 1.00000000000226 2.25808625830976e-12 18 0 0 24 5310 WP2911 miRNA targets in ECM and membrane receptors 1.00000000000231 2.30954632851613e-12 43 0 0 24 5310 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 1.00000000000272 2.71965013171754e-12 31 0 0 24 5310 WP408 Oxidative Stress 1.00000000000272 2.71965013171754e-12 31 0 0 24 5310 WP2112 IL17 signaling pathway 1.00000000000272 2.71965013171754e-12 31 0 0 24 5310 WP411 mRNA Processing 1.00000000000277 2.77112627978053e-12 132 0 0 24 5310 WP1471 Target Of Rapamycin (TOR) Signaling 1.00000000000283 2.82657818195563e-12 37 0 0 24 5310 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR 1.00000000000283 2.82657818195563e-12 37 0 0 24 5310 WP3529 Zinc homeostasis 1.00000000000283 2.82657818195563e-12 37 0 0 24 5310 WP3614 Photodynamic therapy-induced HIF-1 survival signaling 1.00000000000283 2.82657818195563e-12 37 0 0 24 5310 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 1.00000000000303 3.03382545530096e-12 144 0 0 24 5310 WP691 Tamoxifen metabolism 1.00000000000338 3.38283344278976e-12 21 0 0 24 5310 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway 1.00000000000338 3.38283344278976e-12 21 0 0 24 5310 WP2533 Glycerophospholipid Biosynthetic Pathway 1.00000000000338 3.38283344278976e-12 21 0 0 24 5310 WP1602 Nicotine Activity on Dopaminergic Neurons 1.00000000000338 3.38283344278976e-12 21 0 0 24 5310 WP2507 Nanomaterial induced apoptosis 1.00000000000338 3.38283344278976e-12 21 0 0 24 5310 WP1544 MicroRNAs in cardiomyocyte hypertrophy 1.00000000000392 3.91714560108643e-12 102 0 0 24 5310 WP702 Metapathway biotransformation 1.00000000000434 4.34083585402693e-12 177 0 0 24 5310 WP111 Electron Transport Chain 1.00000000000448 4.47839493308259e-12 92 0 0 24 5310 WP289 Myometrial Relaxation and Contraction Pathways 1.00000000000465 4.6466513797131e-12 158 0 0 24 5310 WP2431 Spinal Cord Injury 1.00000000000466 4.65977975844185e-12 119 0 0 24 5310 WP1311 Folic Acid Network 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP2866 mir34a and TGIF2 in osteoclastogenesis 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP1438 Influenza A virus infection 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP2816 Felbamate Metabolism 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP2901 Gonadotropin-releasing hormone (GnRH) signaling 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP2646 Lidocaine metabolism 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP1273 Folic Acid Network 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP2943 Hypoxia-mediated EMT and Stemness 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP2366 Butyrate-induced histone acetylation 1.00000000000485 4.84701779309826e-12 2 0 0 24 5310 WP75 Toll-like Receptor Signaling Pathway 1.00000000000493 4.92872399423732e-12 103 0 0 24 5310 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 1.00000000000501 5.00856228320744e-12 73 0 0 24 5310 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 1.0000000000051 5.09713232708299e-12 23 0 0 24 5310 WP712 Estrogen signaling pathway 1.0000000000051 5.09713232708299e-12 23 0 0 24 5310 WP453 Inflammatory Response Pathway 1.00000000000541 5.41163446769984e-12 33 0 0 24 5310 WP2363 Gastric Cancer Network 2 1.00000000000541 5.41163446769984e-12 33 0 0 24 5310 WP430 Statin Pathway 1.00000000000541 5.41163446769984e-12 33 0 0 24 5310 WP58 Monoamine GPCRs 1.00000000000541 5.41163446769984e-12 33 0 0 24 5310 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway 1.00000000000544 5.44210091364868e-12 68 0 0 24 5310 WP1403 AMP-activated Protein Kinase (AMPK) Signaling 1.00000000000544 5.44210091364868e-12 68 0 0 24 5310 WP3303 Rac1/Pak1/p38/MMP-2 pathway 1.00000000000544 5.44210091364868e-12 68 0 0 24 5310 WP1984 Integrated Breast Cancer Pathway 1.00000000000549 5.48767866152474e-12 154 0 0 24 5310 WP2446 Retinoblastoma (RB) in Cancer 1.000000000006 6.00395678919137e-12 88 0 0 24 5310 WP3925 Amino Acid metabolism 1.00000000000634 6.3440509834688e-12 91 0 0 24 5310 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1.0000000000068 6.79916214599865e-12 162 0 0 24 5310 WP3594 Circadian rythm related genes 1.00000000000744 7.43561128376961e-12 207 0 0 24 5310 WP1455 Serotonin Transporter Activity 1.00000000000751 7.51126681360888e-12 11 0 0 24 5310 WP2513 Nanoparticle triggered regulated necrosis 1.00000000000751 7.51126681360888e-12 11 0 0 24 5310 WP2854 Gene regulatory network modelling somitogenesis 1.00000000000751 7.51126681360888e-12 11 0 0 24 5310 WP3630 NAD metabolism, sirtuins and aging 1.00000000000751 7.51126681360888e-12 11 0 0 24 5310 WP80 Nucleotide GPCRs 1.00000000000751 7.51126681360888e-12 11 0 0 24 5310 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation 1.00000000000792 7.91962445605176e-12 12 0 0 24 5310 WP3672 LncRNA-mediated mechanisms of therapeutic resistance 1.00000000000792 7.91962445605176e-12 12 0 0 24 5310 WP106 Alanine and aspartate metabolism 1.00000000000792 7.91962445605176e-12 12 0 0 24 5310 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ 1.00000000000792 7.91962445605176e-12 12 0 0 24 5310 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy 1.00000000000792 7.91962445605176e-12 12 0 0 24 5310 WP2290 RalA downstream regulated genes 1.00000000000792 7.91962445605176e-12 12 0 0 24 5310 WP15 Selenium Micronutrient Network 1.00000000000851 8.50891076299884e-12 87 0 0 24 5310 WP615 Senescence and Autophagy in Cancer 1.00000000000968 9.67535219988687e-12 106 0 0 24 5310 WP2436 Dopamine metabolism 1.00000000000994 9.94484005878783e-12 14 0 0 24 5310 WP3853 ERK Pathway in Huntington's Disease 1.00000000000994 9.94484005878783e-12 14 0 0 24 5310 WP229 Irinotecan Pathway 1.00000000000994 9.94484005878783e-12 14 0 0 24 5310 WP1591 Heart Development 1.00000000000995 9.9479442453737e-12 46 0 0 24 5310 WP28 Selenium Metabolism and Selenoproteins 1.00000000000995 9.9479442453737e-12 46 0 0 24 5310 WP3878 ATM Signaling Network in Development and Disease 1.00000000000995 9.9479442453737e-12 46 0 0 24 5310 WP465 Tryptophan metabolism 1.00000000000995 9.9479442453737e-12 46 0 0 24 5310 WP1971 Integrated Cancer Pathway 1.00000000000995 9.9479442453737e-12 46 0 0 24 5310 WP536 Calcium Regulation in the Cardiac Cell 1.00000000001313 1.31315086936251e-11 151 0 0 24 5310