Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
9.497e-09	-18.47	brainstem	COSMIC cancer mutations	brainstem	3102	27	16828	49	NKAIN3,RANBP3L,ITPR2,MAML2,NPAS3,LSAMP,FGFR3,PTPRZ1,AHCYL2,RORA,PARD3,PREX2,FBXL7,CTNND2,ZBTB20,SFXN5,ZNRF3,RYR3,TNIK,GPM6A,SLC1A3,CDH20,GPC5,ATP13A4,SLC1A2,PCDH9,SOX5
1.790e-08	-17.84	lymph_node	COSMIC cancer mutations	lymph_node	1703	20	16828	49	SFXN5,RYR3,CAMK2G,DTNA,ITPR2,RANBP3L,CTNND2,TRPS1,PARD3,GPC5,ATP13A4,PCDH9,SOX5,LSAMP,FGFR3,SLC1A3,PARD3B,GPM6A,MAML2,TNIK
2.195e-08	-17.63	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	24	16828	49	RANBP3L,NKAIN3,ITPR2,MAML2,LSAMP,RORA,AHCYL2,PTPRZ1,CTNND2,ZBTB20,PREX2,PARD3,FBXL7,RYR3,ZNRF3,SFXN5,GPM6A,TNIK,ATP13A4,GPC5,SOX5,PCDH9,SLC1A3,CDH20
4.928e-08	-16.83	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	39	16828	49	CTNND2,ZBTB20,PREX2,PARD3,FBXL7,RYR3,ZNRF3,NHSL1,SFXN5,MACF1,PARD3B,RFX4,GPM6A,CST3,TNIK,ABLIM1,ATP13A4,SLC1A2,GPC5,PCDH9,SOX5,HIF3A,CDH20,RANBP3L,TRPS1,CAMK2G,DTNA,ATP1A2,ITPR2,MAML2,NRXN1,SLC4A4,PAMR1,FGFR3,LSAMP,RORA,NTM,PTPRZ1,PITPNC1
5.733e-08	-16.67	nervous system development	biological process	GO:0007399	2185	21	18204	49	BMPR1B,SLC1A2,PTPRZ1,RORA,PCDH9,NTM,RFX4,MSI2,CTNND2,SOX5,ATP1A2,PARD3,NFIA,CTNNA2,CAMK2G,TNIK,GPM6A,SLC1A3,LSAMP,NRXN1,PREX2
7.535e-08	-16.40	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	15	19454	50	TRPS1,GPM6A,MSI2,MAML2,ATP1A2,CAMK2G,SLC1A3,ABLIM1,PTPRZ1,LSAMP,SPARCL1,AHCYL2,MACF1,SLC4A4,NHSL1
1.314e-07	-15.84	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	21	16828	49	PARD3,PREX2,NKAIN3,FBXL7,CTNND2,ITPR2,NHSL1,RYR3,RFX4,GPM6A,MAML2,NPAS3,LSAMP,SLC1A3,AHCYL2,GPC5,BMPR1B,SLC1A2,ATP13A4,SOX5,PCDH9
1.314e-07	-15.84	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	21	16828	49	GPC5,BMPR1B,SLC1A2,ATP13A4,PCDH9,SOX5,LSAMP,SLC1A3,AHCYL2,RFX4,GPM6A,MAML2,NPAS3,NHSL1,RYR3,ITPR2,CTNND2,PARD3,PREX2,NKAIN3,FBXL7
1.940e-07	-15.46	cell morphogenesis	biological process	GO:0000902	687	12	18204	49	CTNND2,BMPR1B,GPM6A,SLC1A3,NRXN1,PREX2,CDH20,PTPRZ1,NFIA,PARD3,CTNNA2,TNIK
2.059e-07	-15.40	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	28	16828	49	MAML2,GLIS3,NRXN1,SLC4A4,RORA,NTM,PTPRZ1,PAMR1,LSAMP,NKAIN3,ITPR2,GPM6A,TNIK,PCDH9,SOX5,HIF3A,SLC1A2,ATP13A4,BMPR1B,GPC5,SLC1A3,ZBTB20,CTNND2,NFIA,FBXL7,PREX2,PARD3,RYR3
2.059e-07	-15.40	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	28	16828	49	PCDH9,HIF3A,SOX5,GPC5,BMPR1B,SLC1A2,ATP13A4,SLC1A3,GPM6A,TNIK,RYR3,ZBTB20,NFIA,CTNND2,FBXL7,PARD3,PREX2,GLIS3,SLC4A4,NRXN1,PTPRZ1,NTM,RORA,LSAMP,PAMR1,MAML2,ITPR2,NKAIN3
3.322e-07	-14.92	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	43	16828	49	DTNA,ITPR2,MAML2,SLC4A4,NRXN1,PTPRZ1,NTM,AHCYL2,RORA,PREX2,SFXN5,NHSL1,ZNRF3,SPARCL1,MACF1,TNIK,GPC5,ATP13A4,SOX5,HIF3A,CDH20,TRPS1,NKAIN3,NPAS3,GLIS3,FGFR3,LSAMP,PITPNC1,NFIA,CTNND2,ZBTB20,PARD3,FBXL7,RYR3,MSI2,PARD3B,RFX4,GPM6A,ABLIM1,BMPR1B,SLC1A2,PCDH9,SLC1A3
3.509e-07	-14.86	multicellular organism development	biological process	GO:0007275	3957	27	18204	49	PCDH9,HIF3A,CDH20,NTM,BMPR1B,SLC1A2,NFIA,SLC1A3,NRXN1,GPM6A,TRPS1,SOX5,CTNND2,RORA,PTPRZ1,FGFR3,ZNRF3,RANBP3L,CAMK2G,TNIK,CTNNA2,PARD3,PREX2,LSAMP,MSI2,RFX4,ATP1A2
6.811e-07	-14.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	15	16828	49	PREX2,PARD3,FBXL7,NKAIN3,NFIA,ATP1A2,RYR3,CAMK2G,TNIK,NPAS3,LSAMP,FGFR3,SLC1A2,BMPR1B,SOX5
6.811e-07	-14.20	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	15	16828	49	RYR3,CAMK2G,ATP1A2,NFIA,FBXL7,NKAIN3,PREX2,PARD3,SOX5,SLC1A2,BMPR1B,LSAMP,FGFR3,NPAS3,TNIK
6.920e-07	-14.18	system development	biological process	GO:0048731	3533	25	18204	49	SOX5,CTNND2,TRPS1,NRXN1,SLC1A3,GPM6A,NFIA,SLC1A2,BMPR1B,NTM,HIF3A,PCDH9,ATP1A2,MSI2,RFX4,LSAMP,PREX2,PARD3,CAMK2G,TNIK,CTNNA2,RANBP3L,FGFR3,RORA,PTPRZ1
7.587e-07	-14.09	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	38	16828	49	NFIA,CTNND2,ZBTB20,PARD3,PREX2,FBXL7,SFXN5,NHSL1,RYR3,MACF1,PARD3B,RFX4,GPM6A,ABLIM1,TNIK,GPC5,ATP13A4,SLC1A2,PCDH9,SOX5,SLC1A3,RANBP3L,TRPS1,NKAIN3,ITPR2,MAML2,NPAS3,SLC4A4,NRXN1,GLIS3,LSAMP,FGFR3,PAMR1,PTPRZ1,PITPNC1,AHCYL2,NTM,RORA
1.354e-06	-13.51	generation of neurons	biological process	GO:0048699	1158	14	18204	49	CTNND2,SOX5,PARD3,NFIA,CTNNA2,TNIK,GPM6A,SLC1A3,NRXN1,PREX2,BMPR1B,PTPRZ1,RORA,NTM
1.377e-06	-13.50	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	12	16828	49	RYR3,ATP1A2,NKAIN3,FBXL7,PARD3,PREX2,SOX5,PCDH9,GPC5,SLC1A2,LSAMP,MAML2
1.475e-06	-13.43	cerebellum	COSMIC cancer mutations	cerebellum	769	12	16828	49	CTNND2,PARD3B,NPAS3,MAML2,PARD3,ABLIM1,NRXN1,RYR3,GPC5,PCDH9,ITPR2,PTPRZ1
2.095e-06	-13.08	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	11	16828	49	MAML2,NPAS3,PARD3B,CTNND2,ABLIM1,PARD3,PCDH9,NRXN1,RYR3,PTPRZ1,ITPR2
2.127e-06	-13.06	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	11	16828	49	ITPR2,PTPRZ1,NRXN1,RYR3,PCDH9,PARD3,ABLIM1,PARD3B,CTNND2,MAML2,NPAS3
2.567e-06	-12.87	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	10	16828	49	LSAMP,AHCYL2,SFXN5,GPC5,RYR3,PCDH9,SOX5,NKAIN3,CTNND2,GPM6A
3.759e-06	-12.49	neuron differentiation	biological process	GO:0030182	1081	13	18204	49	CTNND2,PREX2,GPM6A,NRXN1,SLC1A3,CTNNA2,TNIK,PARD3,NFIA,BMPR1B,NTM,PTPRZ1,RORA
4.244e-06	-12.37	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	18	16828	49	ITPR2,MACF1,RYR3,ZNRF3,ZBTB20,FGFR3,AHCYL2,RORA,NRXN1,SLC4A4,BMPR1B,SOX5,PCDH9,TNIK,PARD3B,NPAS3,MAML2,GPM6A
4.307e-06	-12.36	larynx	COSMIC cancer mutations	larynx	1948	18	16828	49	MACF1,ITPR2,ZNRF3,RYR3,ZBTB20,AHCYL2,RORA,FGFR3,SOX5,PCDH9,SLC4A4,BMPR1B,NRXN1,TNIK,MAML2,GPM6A,NPAS3,PARD3B
4.477e-06	-12.32	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	22	16828	49	TRPS1,NKAIN3,ITPR2,MAML2,LSAMP,CTNND2,FBXL7,PREX2,PARD3,RYR3,SFXN5,ZNRF3,GPM6A,RFX4,PARD3B,HIF3A,PCDH9,SOX5,ATP13A4,SLC1A2,GPC5,SLC1A3
4.871e-06	-12.23	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	27	16828	49	MAML2,RORA,AHCYL2,LSAMP,FGFR3,NKAIN3,TRPS1,RANBP3L,ATP1A2,ITPR2,DTNA,TNIK,GPM6A,SLC1A3,CDH20,PCDH9,SOX5,ATP13A4,SLC1A2,GPC5,FBXL7,PREX2,PARD3,CTNND2,MACF1,SPARCL1,RYR3
5.085e-06	-12.19	neuron projection morphogenesis	biological process	GO:0048812	486	9	18204	49	CTNND2,BMPR1B,GPM6A,NRXN1,PREX2,PTPRZ1,PARD3,CTNNA2,TNIK
5.525e-06	-12.11	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	9	18204	49	CTNND2,BMPR1B,PREX2,GPM6A,NRXN1,CTNNA2,TNIK,PTPRZ1,PARD3
5.996e-06	-12.02	cell projection morphogenesis	biological process	GO:0048858	496	9	18204	49	PREX2,GPM6A,NRXN1,CTNNA2,TNIK,PTPRZ1,PARD3,CTNND2,BMPR1B
7.063e-06	-11.86	multicellular organismal process	biological process	GO:0032501	6177	32	18204	49	HIF3A,CDH20,NTM,PCDH9,SLC1A2,PTGDS,BMPR1B,NRXN1,SLC1A3,GPM6A,NFIA,ABLIM1,SOX5,DTNA,CTNND2,TRPS1,FGFR3,RORA,SLC4A4,PTPRZ1,ZNRF3,RANBP3L,RYR3,PREX2,LSAMP,TNIK,CAMK2G,CTNNA2,PARD3,ATP1A2,MSI2,RFX4
7.103e-06	-11.85	neurogenesis	biological process	GO:0022008	1334	14	18204	49	BMPR1B,PTPRZ1,RORA,NTM,CTNND2,SOX5,NFIA,PARD3,CTNNA2,TNIK,GPM6A,NRXN1,SLC1A3,PREX2
7.143e-06	-11.85	Par3/HAL_N	interpro domains	IPR021922	2	2	18521	50	PARD3B,PARD3
7.570e-06	-11.79	anatomical structure development	biological process	GO:0048856	5207	29	18204	49	NTM,HIF3A,CDH20,PCDH9,SLC1A2,BMPR1B,GPM6A,SLC1A3,NRXN1,ABLIM1,NFIA,CTNND2,SOX5,SPARCL1,TRPS1,FGFR3,PTPRZ1,RORA,RANBP3L,ZNRF3,LSAMP,PREX2,PARD3,CTNNA2,CAMK2G,TNIK,ATP1A2,RFX4,MSI2
7.737e-06	-11.77	Par3_HAL_N_term	pfam domains	PF12053	2	2	17795	50	PARD3B,PARD3
8.073e-06	-11.73	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	9	16828	49	MAML2,GPM6A,CTNND2,PCDH9,SFXN5,GPC5,RYR3,ATP13A4,LSAMP
8.905e-06	-11.63	mouth	COSMIC cancer mutations	mouth	9004	41	16828	49	NTM,RORA,PTPRZ1,PITPNC1,PAMR1,FGFR3,LSAMP,NRXN1,SLC4A4,NPAS3,MAML2,ITPR2,ATP1A2,CAMK2G,DTNA,TRPS1,RANBP3L,CDH20,SLC1A3,HIF3A,SOX5,PCDH9,SLC1A2,ATP13A4,GPC5,TNIK,ABLIM1,CST3,GPM6A,PARD3B,RFX4,MACF1,RYR3,ZNRF3,NHSL1,SFXN5,FBXL7,PREX2,PARD3,ZBTB20,CTNND2
9.076e-06	-11.61	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	26	16828	49	RYR3,ZNRF3,NHSL1,MACF1,CTNND2,NFIA,PREX2,PARD3,FBXL7,SLC1A2,HIF3A,PCDH9,PARD3B,RFX4,GPM6A,TNIK,CAMK2G,ATP1A2,TRPS1,SLC4A4,GLIS3,FGFR3,PTPRZ1,PITPNC1,NPAS3,MAML2
9.412e-06	-11.57	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	21	16828	49	ZNRF3,SFXN5,RYR3,ITPR2,CTNND2,TRPS1,PARD3,PREX2,NKAIN3,FBXL7,GPC5,SLC1A2,SOX5,PCDH9,HIF3A,LSAMP,SLC1A3,PARD3B,RFX4,GPM6A,MAML2
1.006e-05	-11.51	plasma membrane	cellular component	GO:0005886	5538	29	19108	49	PCDH9,NRXN1,PTPRZ1,DTNA,CST3,ATP1A2,HIF3A,FGFR3,NKAIN3,BMPR1B,CDH20,GPM6A,SLC1A3,LSAMP,NTM,MACF1,TNIK,PARD3B,PARD3,CTNND2,ZNRF3,PREX2,GPC5,SLC1A2,ATP13A4,CTNNA2,ITPR2,SLC4A4,RYR3
1.359e-05	-11.21	neuron development	biological process	GO:0048666	859	11	18204	49	BMPR1B,PTPRZ1,NTM,CTNND2,PARD3,CTNNA2,TNIK,GPM6A,SLC1A3,NRXN1,PREX2
1.464e-05	-11.13	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	4	10285	28	CAMK2G,ATP1A2,ITPR2,RYR3
1.584e-05	-11.05	developmental process	biological process	GO:0032502	5716	30	18204	49	MSI2,RFX4,ATP1A2,TNIK,CAMK2G,CTNNA2,PARD3,PREX2,LSAMP,ZNRF3,RANBP3L,RORA,PTPRZ1,FGFR3,TRPS1,SOX5,SPARCL1,CTNND2,NFIA,ABLIM1,SLC1A3,NRXN1,GPM6A,NHSL1,BMPR1B,SLC1A2,PCDH9,CDH20,HIF3A,NTM
1.707e-05	-10.98	cell periphery	cellular component	GO:0071944	6020	30	19108	49	LSAMP,BMPR1B,CDH20,GPM6A,SLC1A3,NKAIN3,FGFR3,MACF1,NTM,DTNA,NRXN1,PTPRZ1,PCDH9,HIF3A,ATP1A2,CST3,ITPR2,CTNNA2,GPC5,SLC1A2,ATP13A4,SPARCL1,SLC4A4,RYR3,PARD3,PARD3B,TNIK,PREX2,ZNRF3,CTNND2
1.766e-05	-10.94	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	3	19454	50	NRXN1,CST3,CTNND2
1.782e-05	-10.94	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	24	16828	49	FGFR3,LSAMP,RORA,AHCYL2,CDH20,SLC1A2,ATP13A4,GPC5,SOX5,PCDH9,TNIK,MAML2,GPM6A,ITPR2,ATP1A2,SPARCL1,MACF1,RYR3,PREX2,PARD3,FBXL7,NKAIN3,CTNND2,RANBP3L
1.836e-05	-10.91	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	7	19454	50	TNIK,DTNA,PARD3,CTNNA2,ABLIM1,NHSL1,MACF1
2.057e-05	-10.79	cell junction	cellular component	GO:0030054	2224	17	19108	49	DTNA,PARD3,TNIK,PCDH9,PARD3B,NRXN1,PTPRZ1,NFIA,CTNND2,ATP1A2,GPM6A,SLC1A3,CDH20,CTNNA2,FGFR3,SLC1A2,SPARCL1
2.170e-05	-10.74	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	8	18204	49	BMPR1B,CTNND2,CTNNA2,PARD3,PTPRZ1,PREX2,NRXN1,SLC1A3
2.544e-05	-10.58	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	18	16828	49	CTNND2,NKAIN3,FBXL7,PARD3,PREX2,RYR3,ITPR2,MAML2,GPM6A,SOX5,PCDH9,GPC5,SLC1A2,CDH20,PTPRZ1,SLC1A3,LSAMP,FGFR3
2.776e-05	-10.49	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	25	16828	49	TRPS1,ATP1A2,CAMK2G,MAML2,NPAS3,FGFR3,PTPRZ1,PITPNC1,SLC4A4,GLIS3,PARD3,PREX2,FBXL7,NFIA,CTNND2,MACF1,ZNRF3,RYR3,TNIK,PARD3B,RFX4,GPM6A,SLC1A2,HIF3A,PCDH9
2.789e-05	-10.49	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	25	16828	49	SLC1A2,PCDH9,HIF3A,RFX4,PARD3B,GPM6A,TNIK,RYR3,ZNRF3,MACF1,CTNND2,NFIA,PREX2,PARD3,FBXL7,SLC4A4,GLIS3,FGFR3,PTPRZ1,PITPNC1,NPAS3,MAML2,CAMK2G,ATP1A2,TRPS1
2.893e-05	-10.45	pharynx	COSMIC cancer mutations	pharynx	2696	20	16828	49	PARD3B,RFX4,NPAS3,FGFR3,PTPRZ1,PITPNC1,ATP13A4,SLC1A2,SLC4A4,GPC5,PCDH9,PREX2,CTNND2,NFIA,ATP1A2,MACF1,DTNA,RYR3,NHSL1,SFXN5
2.908e-05	-10.45	bone	COSMIC cancer mutations	bone	8157	38	16828	49	TRPS1,RANBP3L,NKAIN3,DTNA,CAMK2G,ITPR2,ATP1A2,NPAS3,MAML2,GLIS3,NRXN1,SLC4A4,RORA,AHCYL2,PTPRZ1,PAMR1,FGFR3,LSAMP,ZBTB20,CTNND2,PREX2,PARD3,RYR3,SFXN5,MACF1,SPARCL1,GPM6A,PARD3B,ABLIM1,TNIK,CST3,PCDH9,HIF3A,SOX5,ATP13A4,GPC5,PTGDS,SLC1A3
2.973e-05	-10.42	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	47	16828	49	ZNRF3,SFXN5,NHSL1,SPARCL1,MACF1,PREX2,GPC5,ATP13A4,SOX5,HIF3A,CDH20,TNIK,DTNA,ITPR2,SLC4A4,NRXN1,PAMR1,PTPRZ1,RORA,NTM,AHCYL2,MAML2,RYR3,MSI2,NFIA,CTNND2,ZBTB20,PARD3,FBXL7,BMPR1B,SLC1A2,PCDH9,SLC1A3,PARD3B,RFX4,GPM6A,ABLIM1,CAMK2G,ATP1A2,RANBP3L,TRPS1,NKAIN3,GLIS3,FGFR3,LSAMP,PITPNC1,NPAS3
3.062e-05	-10.39	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	26	16828	49	NHSL1,RYR3,MACF1,ITPR2,TRPS1,ZBTB20,RANBP3L,NFIA,CTNND2,FBXL7,PARD3,PREX2,HIF3A,SOX5,PCDH9,SLC4A4,PTGDS,ATP13A4,CDH20,PTPRZ1,NTM,FGFR3,GPM6A,PARD3B,RFX4,TNIK
3.891e-05	-10.15	anatomical structure morphogenesis	biological process	GO:0009653	2225	17	18204	49	SOX5,CTNND2,NFIA,PARD3,ABLIM1,TNIK,CTNNA2,SLC1A3,NRXN1,GPM6A,PREX2,BMPR1B,RORA,PTPRZ1,FGFR3,HIF3A,CDH20
4.274e-05	-10.06	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	28	SLC1A2,SLC1A3
4.274e-05	-10.06	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	28	SLC1A2,SLC1A3
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A3,SLC1A2
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A2,SLC1A3
7.061e-05	-9.56	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	49	SLC1A2,SLC1A3
7.061e-05	-9.56	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	49	SLC1A3,SLC1A2
7.070e-05	-9.56	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	49	ATP1A2,SLC1A2,SLC1A3
7.145e-05	-9.55	nodular	COSMIC cancer mutations	nodular	1515	14	16828	49	HIF3A,GLIS3,SLC4A4,ATP13A4,PTPRZ1,CDH20,FGFR3,NPAS3,ABLIM1,MACF1,SPARCL1,ATP1A2,CTNND2,PREX2
7.567e-05	-9.49	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	14	16828	49	LSAMP,SLC1A3,RORA,GPC5,PCDH9,SOX5,MAML2,ITPR2,RYR3,PARD3,PREX2,NKAIN3,FBXL7,CTNND2
7.567e-05	-9.49	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	14	16828	49	RYR3,ITPR2,CTNND2,PARD3,PREX2,NKAIN3,FBXL7,GPC5,SOX5,PCDH9,LSAMP,SLC1A3,RORA,MAML2
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	LSAMP,NTM,GPM6A
8.356e-05	-9.39	neuron projection development	biological process	GO:0031175	693	9	18204	49	PTPRZ1,PARD3,CTNNA2,TNIK,GPM6A,NRXN1,PREX2,BMPR1B,CTNND2
8.364e-05	-9.39	vascular transport	biological process	GO:0010232	86	4	18204	49	SLC1A2,SLC1A3,ATP1A2,SLC4A4
8.364e-05	-9.39	transport across blood-brain barrier	biological process	GO:0150104	86	4	18204	49	SLC4A4,ATP1A2,SLC1A3,SLC1A2
8.772e-05	-9.34	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	17	16828	49	ITPR2,RYR3,NKAIN3,FBXL7,PARD3,PREX2,CTNND2,PTPRZ1,SLC1A3,CDH20,LSAMP,SOX5,PCDH9,GPC5,SLC1A2,GPM6A,MAML2
8.772e-05	-9.34	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	17	16828	49	SLC1A2,GPC5,PCDH9,SOX5,LSAMP,PTPRZ1,CDH20,SLC1A3,MAML2,GPM6A,RYR3,ITPR2,CTNND2,PREX2,PARD3,FBXL7,NKAIN3
9.079e-05	-9.31	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	48	16828	49	ZNRF3,SFXN5,NHSL1,MACF1,PREX2,HIF3A,SOX5,ATP13A4,GPC5,CDH20,TNIK,CST3,DTNA,ITPR2,NRXN1,SLC4A4,RORA,AHCYL2,NTM,PTPRZ1,PAMR1,MAML2,MSI2,RYR3,ZBTB20,CTNND2,NFIA,FBXL7,PARD3,PCDH9,SLC1A2,BMPR1B,PTGDS,SLC1A3,GPM6A,PARD3B,RFX4,ABLIM1,CAMK2G,ATP1A2,TRPS1,RANBP3L,NKAIN3,GLIS3,PITPNC1,FGFR3,LSAMP,NPAS3
9.447e-05	-9.27	response to auditory stimulus	biological process	GO:0010996	33	3	18204	49	ATP1A2,NRXN1,SLC1A3
9.692e-05	-9.24	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	20	ITPR2,ATP1A2,CST3,RYR3
9.692e-05	-9.24	Salivary secretion	KEGG pathways	ko04970	90	4	7161	20	ITPR2,RYR3,CST3,ATP1A2
1.023e-04	-9.19	neuron projection	cellular component	GO:0043005	1331	12	19108	49	CTNND2,ATP1A2,PCDH9,AHCYL2,DTNA,PARD3,CAMK2G,SLC1A2,CTNNA2,BMPR1B,GPM6A,SLC1A3
1.057e-04	-9.15	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	49	SLC1A3,SLC1A2
1.057e-04	-9.15	D-amino acid transport	biological process	GO:0042940	6	2	18204	49	SLC1A3,SLC1A2
1.064e-04	-9.15	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	RIH_dom	interpro domains	IPR000699	6	2	18521	50	ITPR2,RYR3
1.064e-04	-9.15	Ins145_P3_rcpt	interpro domains	IPR014821	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	RIH_assoc-dom	interpro domains	IPR013662	6	2	18521	50	RYR3,ITPR2
1.064e-04	-9.15	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	2	18521	50	ITPR2,RYR3
1.152e-04	-9.07	Ins145_P3_rec	pfam domains	PF08709	6	2	17795	50	ITPR2,RYR3
1.152e-04	-9.07	RIH_assoc	pfam domains	PF08454	6	2	17795	50	RYR3,ITPR2
1.152e-04	-9.07	RYDR_ITPR	pfam domains	PF01365	6	2	17795	50	RYR3,ITPR2
1.173e-04	-9.05	adherens junction	cellular component	GO:0005912	188	5	19108	49	PARD3B,CTNND2,PARD3,CDH20,CTNNA2
1.219e-04	-9.01	tibia	COSMIC cancer mutations	tibia	836	10	16828	49	PREX2,TNIK,ABLIM1,NKAIN3,CTNND2,RANBP3L,GPM6A,FGFR3,LSAMP,MACF1
1.249e-04	-8.99	MAPT (microtubule associated protein tau)	protein interactions	4137	948	10	19454	50	ABLIM1,SLC1A3,ATP1A2,NTM,LSAMP,TNIK,SLC1A2,CTNND2,CTNNA2,GPM6A
1.275e-04	-8.97	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	30	16828	49	PARD3B,GPM6A,CDH20,SLC1A3,SLC1A2,GPC5,PCDH9,SOX5,PREX2,PARD3,FBXL7,CTNND2,NFIA,SPARCL1,MACF1,RYR3,ZNRF3,NHSL1,NPAS3,MAML2,PAMR1,LSAMP,FGFR3,RORA,PTPRZ1,GLIS3,NKAIN3,TRPS1,ITPR2,CAMK2G
1.329e-04	-8.93	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	22	16828	49	MSI2,ZNRF3,DTNA,RYR3,MACF1,RANBP3L,CTNND2,FBXL7,PARD3,PREX2,PCDH9,BMPR1B,SLC4A4,GPC5,PTPRZ1,SLC1A3,PITPNC1,LSAMP,PAMR1,NPAS3,PARD3B,TNIK
1.329e-04	-8.93	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	22	16828	49	PARD3B,TNIK,GPC5,BMPR1B,PCDH9,SLC1A3,CTNND2,PREX2,PARD3,FBXL7,RYR3,ZNRF3,MSI2,MACF1,NPAS3,SLC4A4,PAMR1,LSAMP,PITPNC1,PTPRZ1,RANBP3L,DTNA
1.345e-04	-8.91	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	2	14470	44	RYR3,ITPR2
1.374e-04	-8.89	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	6	19454	50	PARD3,TNIK,ABLIM1,AHCYL2,DTNA,MACF1
1.378e-04	-8.89	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	9	18094	48	ITPR2,ATP13A4,SLC1A2,ATP1A2,SLC4A4,GPM6A,SLC1A3,RYR3,SFXN5
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.534e-04	-8.78	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	7	18094	48	RYR3,GPM6A,ATP1A2,SLC1A3,SLC1A2,SLC4A4,ITPR2
1.565e-04	-8.76	cellular response to alkaloid	biological process	GO:0071312	39	3	18204	49	RYR3,SLC1A3,SLC1A2
1.603e-04	-8.74	trunk	COSMIC cancer mutations	trunk	3554	22	16828	49	MAML2,NPAS3,PTPRZ1,FGFR3,LSAMP,GLIS3,NRXN1,TRPS1,ATP1A2,ABLIM1,CDH20,SLC1A3,PCDH9,HIF3A,SOX5,ATP13A4,PARD3,PREX2,CTNND2,MACF1,SPARCL1,RYR3
1.610e-04	-8.73	SDF	pfam domains	PF00375	7	2	17795	50	SLC1A3,SLC1A2
1.627e-04	-8.72	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	5	19454	50	PARD3,CAMK2G,RYR3,DTNA,ATP1A2
1.628e-04	-8.72	humerus	COSMIC cancer mutations	humerus	546	8	16828	49	GPM6A,PARD3B,NKAIN3,HIF3A,SOX5,SFXN5,GPC5,AHCYL2
1.707e-04	-8.68	cell adhesion	biological process	GO:0007155	942	10	18204	49	CDH20,NTM,LSAMP,NRXN1,PCDH9,CTNNA2,PARD3,CTNND2,SPARCL1,PARD3B
1.810e-04	-8.62	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	41	16828	49	FBXL7,PARD3,PREX2,NFIA,CTNND2,MACF1,SPARCL1,MSI2,ZNRF3,RYR3,ABLIM1,TNIK,CST3,GPM6A,PARD3B,RFX4,CDH20,HIF3A,SOX5,PCDH9,GPC5,BMPR1B,ATP13A4,NKAIN3,TRPS1,RANBP3L,ITPR2,ATP1A2,CAMK2G,DTNA,MAML2,NPAS3,PTPRZ1,PITPNC1,NTM,AHCYL2,RORA,FGFR3,PAMR1,SLC4A4,NRXN1
1.820e-04	-8.61	sarcoplasmic reticulum membrane	cellular component	GO:0033017	43	3	19108	49	RYR3,CAMK2G,ITPR2
1.838e-04	-8.60	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	41	16828	49	PAMR1,FGFR3,RORA,NTM,AHCYL2,PITPNC1,PTPRZ1,NRXN1,SLC4A4,NPAS3,MAML2,ITPR2,ATP1A2,CAMK2G,DTNA,NKAIN3,RANBP3L,TRPS1,CDH20,ATP13A4,GPC5,BMPR1B,HIF3A,PCDH9,SOX5,CST3,ABLIM1,TNIK,RFX4,PARD3B,GPM6A,SPARCL1,MACF1,RYR3,ZNRF3,MSI2,PREX2,PARD3,FBXL7,CTNND2,NFIA
1.841e-04	-8.60	beta-catenin binding	molecular function	GO:0008013	107	4	18094	48	CDH20,RORA,CTNND2,CTNNA2
1.870e-04	-8.58	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	4	10285	28	SLC1A2,AHCYL2,SLC1A3,SLC4A4
1.874e-04	-8.58	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	49	NKAIN3,LSAMP,GPM6A,CTNND2
1.879e-04	-8.58	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	44	SLC1A3,SLC1A2
1.949e-04	-8.54	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	11	18204	49	PTPRZ1,BMPR1B,CTNNA2,TNIK,ABLIM1,PARD3,PREX2,GPM6A,NRXN1,RFX4,CTNND2
2.008e-04	-8.51	scalp	COSMIC cancer mutations	scalp	2110	16	16828	49	CAMK2G,ATP1A2,MACF1,NFIA,TRPS1,PREX2,ATP13A4,NRXN1,GPC5,SLC4A4,SOX5,LSAMP,FGFR3,RORA,NTM,PTPRZ1
2.071e-04	-8.48	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	49	ITPR2,ATP1A2,DTNA,NKAIN3,TRPS1,RANBP3L,AHCYL2,RORA,NTM,PTPRZ1,PITPNC1,PAMR1,FGFR3,LSAMP,GLIS3,NRXN1,SLC4A4,NPAS3,MACF1,RYR3,ZNRF3,SFXN5,FBXL7,PREX2,PARD3,ZBTB20,CTNND2,NFIA,SLC1A3,CDH20,HIF3A,SOX5,PCDH9,ATP13A4,SLC1A2,BMPR1B,GPC5,TNIK,ABLIM1,GPM6A,PARD3B,RFX4
2.071e-04	-8.48	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	49	PARD3B,RFX4,GPM6A,TNIK,ABLIM1,GPC5,BMPR1B,SLC1A2,ATP13A4,HIF3A,SOX5,PCDH9,CDH20,SLC1A3,NFIA,CTNND2,ZBTB20,PARD3,PREX2,FBXL7,SFXN5,ZNRF3,RYR3,MACF1,NPAS3,SLC4A4,NRXN1,GLIS3,FGFR3,LSAMP,PAMR1,PITPNC1,PTPRZ1,AHCYL2,NTM,RORA,RANBP3L,TRPS1,NKAIN3,DTNA,ITPR2,ATP1A2
2.276e-04	-8.39	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	8	18094	48	GPM6A,SLC4A4,ATP13A4,SLC1A2,ATP1A2,ITPR2,RYR3,SLC1A3
2.282e-04	-8.39	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	6	16828	49	NKAIN3,AHCYL2,SFXN5,GPC5,SOX5,GPM6A
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	NTM,LSAMP
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	NTM,LSAMP
2.531e-04	-8.28	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	12	16828	49	PREX2,ABLIM1,CTNND2,NPAS3,SPARCL1,ATP1A2,CDH20,PTPRZ1,MACF1,ATP13A4,HIF3A,GLIS3
2.561e-04	-8.27	monoatomic ion transmembrane transport	biological process	GO:0034220	804	9	18204	49	ATP1A2,SLC1A2,RYR3,ATP13A4,GPM6A,ITPR2,SLC1A3,SFXN5,SLC4A4
2.601e-04	-8.25	EDTRNSPORT	prints domains	PR00173	7	2	5227	19	SLC1A2,SLC1A3
2.645e-04	-8.24	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	44	SLC1A3,SLC1A2
2.645e-04	-8.24	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	44	SLC1A3,SLC1A2
2.780e-04	-8.19	cell projection organization	biological process	GO:0030030	1200	11	18204	49	CTNND2,BMPR1B,RFX4,GPM6A,NRXN1,PREX2,PTPRZ1,ABLIM1,PARD3,CTNNA2,TNIK
2.833e-04	-8.17	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	35	16828	49	RFX4,GPM6A,ABLIM1,TNIK,BMPR1B,GPC5,ATP13A4,SLC1A2,SOX5,PCDH9,SLC1A3,CDH20,CTNND2,PARD3,PREX2,FBXL7,NHSL1,SFXN5,RYR3,MACF1,MAML2,SLC4A4,GLIS3,LSAMP,FGFR3,PAMR1,PTPRZ1,RORA,AHCYL2,RANBP3L,TRPS1,NKAIN3,CAMK2G,ITPR2,ATP1A2
3.121e-04	-8.07	cell-cell junction	cellular component	GO:0005911	513	7	19108	49	PARD3,CDH20,CTNNA2,PARD3B,PCDH9,ATP1A2,CTNND2
3.150e-04	-8.06	establishment of centrosome localization	biological process	GO:0051660	10	2	18204	49	PARD3,PARD3B
3.150e-04	-8.06	cellular response to cocaine	biological process	GO:0071314	10	2	18204	49	SLC1A3,SLC1A2
3.162e-04	-8.06	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	4	19454	50	DTNA,ABLIM1,PARD3,MACF1
3.170e-04	-8.06	MIR_motif	interpro domains	IPR016093	10	2	18521	50	ITPR2,RYR3
3.170e-04	-8.06	MIR_dom_sf	interpro domains	IPR036300	10	2	18521	50	RYR3,ITPR2
3.173e-04	-8.06	Bicarbonate transporters	REACTOME pathways	R-HSA-425381	10	2	10285	28	SLC4A4,AHCYL2
3.226e-04	-8.04	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	8	10285	28	CAMK2G,SLC4A4,RYR3,SLC1A2,SLC1A3,AHCYL2,ATP13A4,ATP1A2
3.346e-04	-8.00	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	4	16828	49	PREX2,SLC1A2,RYR3,SOX5
3.432e-04	-7.98	MIR	pfam domains	PF02815	10	2	17795	50	RYR3,ITPR2
3.844e-04	-7.86	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	49	SLC1A2,SLC1A3
3.844e-04	-7.86	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	49	SLC1A2,SLC1A3
3.906e-04	-7.85	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	49	TRPS1,BMPR1B,SOX5
3.918e-04	-7.84	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	31	16828	49	ITPR2,ATP1A2,TRPS1,RANBP3L,GLIS3,SLC4A4,NRXN1,PTPRZ1,PITPNC1,FGFR3,MAML2,NPAS3,SFXN5,RYR3,MACF1,SPARCL1,ZBTB20,CTNND2,FBXL7,PARD3,PREX2,PCDH9,SOX5,HIF3A,BMPR1B,GPC5,ATP13A4,GPM6A,PARD3B,ABLIM1,TNIK
3.988e-04	-7.83	Myo1c (myosin IC)	protein interactions	17913	135	4	19454	50	TRPS1,ITPR2,ABLIM1,CAMK2G
4.439e-04	-7.72	NAKATPASE	prints domains	PR00121	9	2	5227	19	ATP1A2,ATP13A4
4.605e-04	-7.68	auditory behavior	biological process	GO:0031223	12	2	18204	49	NRXN1,SLC1A3
4.673e-04	-7.67	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	15	16828	49	TRPS1,PARD3,PREX2,ZNRF3,MSI2,ITPR2,MACF1,GPM6A,ABLIM1,GPC5,PCDH9,FGFR3,LSAMP,PTPRZ1,RORA
4.806e-04	-7.64	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	33	16828	49	ITPR2,ATP1A2,RANBP3L,TRPS1,NRXN1,SLC4A4,LSAMP,FGFR3,RORA,NTM,PITPNC1,PTPRZ1,NPAS3,MAML2,RYR3,SFXN5,ZNRF3,NHSL1,MACF1,CTNND2,NFIA,ZBTB20,PREX2,PARD3,FBXL7,ATP13A4,SLC1A2,PCDH9,SOX5,CDH20,PARD3B,RFX4,CST3
4.806e-04	-7.64	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	33	16828	49	ATP1A2,ITPR2,TRPS1,RANBP3L,SLC4A4,NRXN1,PTPRZ1,PITPNC1,NTM,RORA,FGFR3,LSAMP,MAML2,NPAS3,ZNRF3,NHSL1,SFXN5,RYR3,MACF1,ZBTB20,NFIA,CTNND2,FBXL7,PARD3,PREX2,PCDH9,SOX5,SLC1A2,ATP13A4,CDH20,PARD3B,RFX4,CST3
5.044e-04	-7.59	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	3	10285	28	ATP1A2,ATP13A4,CAMK2G
5.060e-04	-7.59	cell body	cellular component	GO:0044297	556	7	19108	49	CTNND2,ATP1A2,GPM6A,SLC1A3,BMPR1B,SLC1A2,NRXN1
5.090e-04	-7.58	Calml3 (calmodulin-like 3)	protein interactions	70405	144	4	19454	50	CAMK2G,ABLIM1,ZBTB20,MACF1
5.187e-04	-7.56	cell junction organization	biological process	GO:0034330	532	7	18204	49	SPARCL1,CTNND2,NFIA,PARD3,NRXN1,GPM6A,CDH20
5.428e-04	-7.52	neurotransmitter transport	biological process	GO:0006836	140	4	18204	49	ATP1A2,NRXN1,SLC1A2,SLC1A3
5.512e-04	-7.50	Cardiac conduction	REACTOME pathways	R-HSA-5576891	142	4	10285	28	ITPR2,RYR3,CAMK2G,ATP1A2
5.629e-04	-7.48	MIR	prosite domains	PS50919	10	2	12186	44	ITPR2,RYR3
5.776e-04	-7.46	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	2	19454	50	ZBTB20,CAMK2G
5.787e-04	-7.45	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	11	16828	49	RANBP3L,CTNND2,PARD3,NKAIN3,TNIK,GPC5,PCDH9,SOX5,LSAMP,ITPR2,RORA
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A3,SLC1A2
6.239e-04	-7.38	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	12	16828	49	ATP1A2,NHSL1,SFXN5,PREX2,CTNND2,NFIA,PITPNC1,FGFR3,ATP13A4,SLC1A2,SLC4A4,RFX4
6.239e-04	-7.38	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	12	16828	49	CTNND2,NFIA,RFX4,PREX2,ATP13A4,SLC1A2,NHSL1,SFXN5,SLC4A4,ATP1A2,FGFR3,PITPNC1
6.327e-04	-7.37	mechanosensory behavior	biological process	GO:0007638	14	2	18204	49	SLC1A3,NRXN1
6.327e-04	-7.37	sodium ion export across plasma membrane	biological process	GO:0036376	14	2	18204	49	ATP1A2,SLC4A4
6.356e-04	-7.36	adult behavior	biological process	GO:0030534	146	4	18204	49	PREX2,ATP1A2,SLC1A2,NRXN1
6.654e-04	-7.32	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	2	19454	50	TNIK,PARD3
6.803e-04	-7.29	dendrite morphogenesis	biological process	GO:0048813	64	3	18204	49	CTNNA2,PREX2,CTNND2
6.922e-04	-7.28	MIR	smart domains	SM00472	10	2	9717	39	RYR3,ITPR2
6.932e-04	-7.27	cell projection	cellular component	GO:0042995	2398	15	19108	49	AHCYL2,DTNA,PARD3,PCDH9,NRXN1,CTNND2,ATP1A2,BMPR1B,CTNNA2,SLC1A3,GPM6A,ABLIM1,CAMK2G,SLC1A2,MACF1
7.721e-04	-7.17	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	5	18094	48	SLC4A4,ATP1A2,SLC1A2,SLC1A3,ATP13A4
7.916e-04	-7.14	face	COSMIC cancer mutations	face	2139	15	16828	49	MACF1,ITPR2,MSI2,ZNRF3,PARD3,PREX2,TRPS1,PTPRZ1,RORA,LSAMP,FGFR3,PCDH9,GPC5,ABLIM1,GPM6A
8.077e-04	-7.12	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	48	SLC4A4,SLC1A2,SLC1A3,ATP1A2
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	LSAMP,ZBTB20
8.315e-04	-7.09	asymmetric cell division	biological process	GO:0008356	16	2	18204	49	PARD3,SOX5
8.340e-04	-7.09	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	11	16828	49	CTNND2,TRPS1,RYR3,MACF1,GPM6A,TNIK,ABLIM1,ATP13A4,PAMR1,FGFR3,NTM
8.340e-04	-7.09	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	11	16828	49	CTNND2,TRPS1,MACF1,RYR3,ABLIM1,TNIK,GPM6A,FGFR3,PAMR1,NTM,ATP13A4
8.632e-04	-7.05	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	7	18094	48	ATP1A2,SLC1A2,SLC4A4,GPM6A,ITPR2,SLC1A3,RYR3
9.003e-04	-7.01	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	7	19454	50	ABLIM1,NHSL1,AHCYL2,FGFR3,TNIK,DTNA,PARD3
9.479e-04	-6.96	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	44	16828	49	NPAS3,GLIS3,FGFR3,LSAMP,PITPNC1,RANBP3L,TRPS1,ATP1A2,RFX4,PARD3B,GPM6A,ABLIM1,BMPR1B,SLC1A2,PCDH9,SLC1A3,NFIA,CTNND2,ZBTB20,PARD3,FBXL7,RYR3,MAML2,SLC4A4,NRXN1,PAMR1,PTPRZ1,NTM,RORA,DTNA,ITPR2,CST3,TNIK,GPC5,ATP13A4,SOX5,HIF3A,CDH20,PREX2,SFXN5,ZNRF3,NHSL1,SPARCL1,MACF1
9.557e-04	-6.95	monoatomic ion transport	biological process	GO:0006811	964	9	18204	49	SLC4A4,SFXN5,SLC1A3,ITPR2,GPM6A,ATP13A4,RYR3,SLC1A2,ATP1A2
9.587e-04	-6.95	cervix	COSMIC cancer mutations	cervix	11793	44	16828	49	CST3,TNIK,CDH20,ATP13A4,GPC5,SOX5,HIF3A,PREX2,SPARCL1,MACF1,NHSL1,ZNRF3,SFXN5,MAML2,PAMR1,NTM,RORA,PTPRZ1,NRXN1,SLC4A4,ITPR2,DTNA,ABLIM1,RFX4,PARD3B,GPM6A,SLC1A3,SLC1A2,BMPR1B,PCDH9,PARD3,FBXL7,CTNND2,NFIA,ZBTB20,RYR3,NPAS3,LSAMP,FGFR3,PITPNC1,GLIS3,RANBP3L,TRPS1,ATP1A2
9.648e-04	-6.94	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	2	19454	50	FGFR3,PARD3
9.763e-04	-6.93	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	5	16828	49	FGFR3,PREX2,SOX5,SLC1A2,RYR3
9.767e-04	-6.93	sarcoplasmic reticulum	cellular component	GO:0016529	76	3	19108	49	ITPR2,RYR3,CAMK2G
9.985e-04	-6.91	regulation of cartilage development	biological process	GO:0061035	73	3	18204	49	SOX5,TRPS1,BMPR1B
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	NTM,GPM6A,LSAMP
1.026e-03	-6.88	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	2	18094	48	RYR3,ITPR2
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A3,SLC1A2
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP13A4,ATP1A2
1.096e-03	-6.82	transporter activity	molecular function	GO:0005215	1211	10	18094	48	SLC1A3,RYR3,SFXN5,ITPR2,PITPNC1,ATP13A4,SLC1A2,ATP1A2,SLC4A4,GPM6A
1.107e-03	-6.81	Gastric acid secretion	KEGG pathways	ko04971	75	3	7161	20	ITPR2,ATP1A2,CAMK2G
1.107e-03	-6.81	Gastric acid secretion	KEGG pathways	hsa04971	75	3	7161	20	ITPR2,ATP1A2,CAMK2G
1.150e-03	-6.77	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	50	ATP13A4,ATP1A2
1.171e-03	-6.75	EPHA4 (EPH receptor A4)	protein interactions	2043	180	4	19454	50	PARD3,FGFR3,AHCYL2,CTNNA2
1.179e-03	-6.74	cartilage condensation	biological process	GO:0001502	19	2	18204	49	SOX5,BMPR1B
1.179e-03	-6.74	RHOB (ras homolog family member B)	protein interactions	388	832	8	19454	50	DTNA,AHCYL2,TNIK,PARD3B,PARD3,MACF1,SLC1A3,ABLIM1
1.186e-03	-6.74	PAS_fold	interpro domains	IPR013767	19	2	18521	50	NPAS3,HIF3A
1.195e-03	-6.73	central nervous system development	biological process	GO:0007417	995	9	18204	49	CTNNA2,PCDH9,PTPRZ1,RORA,ATP1A2,SLC1A2,BMPR1B,RFX4,MSI2
1.196e-03	-6.73	cartilage development	biological process	GO:0051216	173	4	18204	49	BMPR1B,NFIA,FGFR3,SOX5
1.203e-03	-6.72	Axon guidance	KEGG pathways	ko04360	174	4	7161	20	BMPR1B,ABLIM1,PARD3,CAMK2G
1.203e-03	-6.72	Axon guidance	KEGG pathways	hsa04360	174	4	7161	20	PARD3,CAMK2G,BMPR1B,ABLIM1
1.226e-03	-6.70	GSC (goosecoid homeobox)	protein interactions	145258	82	3	19454	50	TRPS1,NFIA,SOX5
1.247e-03	-6.69	solute:sodium symporter activity	molecular function	GO:0015370	80	3	18094	48	SLC1A3,SLC1A2,SLC4A4
1.283e-03	-6.66	PAS	pfam domains	PF00989	19	2	17795	50	NPAS3,HIF3A
1.290e-03	-6.65	plasma membrane region	cellular component	GO:0098590	1278	10	19108	49	TNIK,PARD3B,SLC1A2,NRXN1,SLC1A3,GPM6A,PARD3,ATP1A2,SLC4A4,MACF1
1.307e-03	-6.64	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	49	SLC1A2,SLC1A3
1.307e-03	-6.64	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	49	BMPR1B,SOX5
1.314e-03	-6.63	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	8	16828	49	DTNA,SOX5,ITPR2,SLC1A3,RANBP3L,CTNND2,TRPS1,PARD3
1.357e-03	-6.60	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	14	19108	49	ATP1A2,CTNND2,PARD3,AHCYL2,DTNA,PCDH9,MACF1,ABLIM1,CTNNA2,BMPR1B,SLC1A3,GPM6A,SLC1A2,CAMK2G
1.439e-03	-6.54	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	22	16828	49	TNIK,PTPRZ1,LSAMP,FGFR3,GLIS3,HIF3A,SOX5,PCDH9,ATP13A4,NRXN1,GPC5,PARD3,TRPS1,CTNND2,NFIA,MACF1,ATP1A2,ITPR2,SPARCL1,DTNA,RYR3,ZNRF3
1.443e-03	-6.54	positive regulation of purine nucleotide catabolic process	biological process	GO:0033123	21	2	18204	49	SLC4A4,ZBTB20
1.443e-03	-6.54	positive regulation of glycolytic process	biological process	GO:0045821	21	2	18204	49	ZBTB20,SLC4A4
1.443e-03	-6.54	cell aggregation	biological process	GO:0098743	21	2	18204	49	BMPR1B,SOX5
1.443e-03	-6.54	positive regulation of nucleotide catabolic process	biological process	GO:0030813	21	2	18204	49	ZBTB20,SLC4A4
1.467e-03	-6.52	cellular response to organic cyclic compound	biological process	GO:0071407	464	6	18204	49	ATP1A2,ITPR2,SLC1A3,RYR3,SLC1A2,RORA
1.474e-03	-6.52	monoatomic cation transmembrane transport	biological process	GO:0098655	636	7	18204	49	SLC4A4,GPM6A,ITPR2,ATP13A4,SLC1A3,RYR3,ATP1A2
1.499e-03	-6.50	neuronal cell body	cellular component	GO:0043025	489	6	19108	49	CTNND2,NRXN1,ATP1A2,BMPR1B,GPM6A,SLC1A3
1.550e-03	-6.47	chondrocyte differentiation	biological process	GO:0002062	85	3	18204	49	FGFR3,SOX5,BMPR1B
1.563e-03	-6.46	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	42	16828	49	PREX2,PARD3,FBXL7,CTNND2,NFIA,SPARCL1,MACF1,RYR3,SFXN5,NHSL1,MSI2,ABLIM1,TNIK,RFX4,PARD3B,CDH20,SLC1A3,SLC1A2,ATP13A4,GPC5,BMPR1B,PCDH9,SOX5,HIF3A,NKAIN3,RANBP3L,ATP1A2,ITPR2,CAMK2G,DTNA,NPAS3,MAML2,PAMR1,FGFR3,LSAMP,AHCYL2,RORA,NTM,PTPRZ1,NRXN1,SLC4A4,GLIS3
1.584e-03	-6.45	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	49	ATP1A2,SLC1A3
1.636e-03	-6.42	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	32	16828	49	GLIS3,PAMR1,LSAMP,AHCYL2,RORA,PTPRZ1,MAML2,ITPR2,RANBP3L,NKAIN3,SLC1A2,ATP13A4,BMPR1B,GPC5,PCDH9,SOX5,CDH20,SLC1A3,PARD3B,RFX4,GPM6A,ABLIM1,TNIK,RYR3,SFXN5,NHSL1,SPARCL1,MACF1,CTNND2,PREX2,PARD3,FBXL7
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.689e-03	-6.38	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	12	16828	49	ATP1A2,MACF1,TRPS1,SLC4A4,GPC5,ATP13A4,NRXN1,SOX5,LSAMP,FGFR3,PTPRZ1,RORA
1.715e-03	-6.37	human chr5p13.2	chromosome location	human chr5p13.2	32	2	26134	50	SLC1A3,RANBP3L
1.748e-03	-6.35	parathyroid-carcinoma	COSMIC cancer mutations	parathyroid-carcinoma	300	5	16828	49	TRPS1,GPC5,RYR3,MACF1,PAMR1
1.758e-03	-6.34	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	27	16828	49	ATP13A4,GPC5,SOX5,CDH20,SLC1A3,PARD3B,GPM6A,CST3,RYR3,ZNRF3,MACF1,CTNND2,PARD3,FBXL7,SLC4A4,PAMR1,LSAMP,NTM,AHCYL2,PTPRZ1,NPAS3,MAML2,DTNA,ATP1A2,ITPR2,TRPS1,NKAIN3
1.758e-03	-6.34	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	27	16828	49	RYR3,ZNRF3,MACF1,CTNND2,FBXL7,PARD3,SOX5,ATP13A4,GPC5,SLC1A3,CDH20,GPM6A,PARD3B,CST3,DTNA,ITPR2,ATP1A2,TRPS1,NKAIN3,SLC4A4,NTM,AHCYL2,PTPRZ1,PAMR1,LSAMP,NPAS3,MAML2
1.781e-03	-6.33	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	41	16828	49	CST3,TNIK,PARD3B,CDH20,SLC1A3,ATP13A4,SLC1A2,GPC5,PTGDS,BMPR1B,SOX5,PCDH9,PREX2,PARD3,FBXL7,CTNND2,ZBTB20,MACF1,RYR3,SFXN5,ZNRF3,NHSL1,MSI2,NPAS3,MAML2,PAMR1,FGFR3,LSAMP,RORA,NTM,AHCYL2,PTPRZ1,NRXN1,SLC4A4,GLIS3,RANBP3L,TRPS1,ITPR2,ATP1A2,CAMK2G,DTNA
1.792e-03	-6.32	gallbladder	COSMIC cancer mutations	gallbladder	2821	17	16828	49	NHSL1,ZNRF3,RYR3,MACF1,SPARCL1,ITPR2,TRPS1,CTNND2,NKAIN3,PARD3,PREX2,PCDH9,SLC4A4,PTPRZ1,PITPNC1,FGFR3,TNIK
1.792e-03	-6.32	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	17	16828	49	SPARCL1,ITPR2,MACF1,ZNRF3,NHSL1,RYR3,PARD3,PREX2,NKAIN3,CTNND2,TRPS1,FGFR3,PTPRZ1,PITPNC1,SLC4A4,PCDH9,TNIK
1.810e-03	-6.31	Proximal tubule bicarbonate reclamation	KEGG pathways	ko04964	23	2	7161	20	SLC4A4,ATP1A2
1.810e-03	-6.31	Proximal tubule bicarbonate reclamation	KEGG pathways	hsa04964	23	2	7161	20	SLC4A4,ATP1A2
1.818e-03	-6.31	Cation_ATPase_N	smart domains	SM00831	16	2	9717	39	ATP1A2,ATP13A4
1.832e-03	-6.30	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	48	ATP1A2,ATP13A4
1.832e-03	-6.30	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	48	ATP13A4,ATP1A2
1.854e-03	-6.29	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	4	19454	50	PARD3B,NRXN1,DTNA,ABLIM1
1.866e-03	-6.28	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	9	16828	49	CTNND2,PARD3,NKAIN3,GPC5,SOX5,PCDH9,ITPR2,LSAMP,RORA
1.901e-03	-6.27	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	28	SLC1A2,SLC1A3
1.911e-03	-6.26	cell differentiation	biological process	GO:0030154	3645	19	18204	49	PTPRZ1,RORA,NTM,FGFR3,BMPR1B,NHSL1,RANBP3L,PARD3,NFIA,CTNNA2,TNIK,CAMK2G,GPM6A,SLC1A3,NRXN1,PREX2,MSI2,CTNND2,SOX5
1.913e-03	-6.26	human chr15q13.3-q14	chromosome location	human chr15q13.3-q14	1	1	26134	50	RYR3
1.913e-03	-6.26	human chr10p11.22-p11.21	chromosome location	human chr10p11.22-p11.21	1	1	26134	50	PARD3
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.915e-03	-6.26	sarcoplasm	cellular component	GO:0016528	96	3	19108	49	ITPR2,RYR3,CAMK2G
1.928e-03	-6.25	anchoring junction	cellular component	GO:0070161	902	8	19108	49	ATP1A2,CTNND2,PARD3B,FGFR3,PCDH9,PARD3,CDH20,CTNNA2
1.931e-03	-6.25	cellular developmental process	biological process	GO:0048869	3648	19	18204	49	RANBP3L,BMPR1B,NHSL1,FGFR3,NTM,PTPRZ1,RORA,CTNND2,SOX5,MSI2,PREX2,GPM6A,SLC1A3,NRXN1,CTNNA2,CAMK2G,TNIK,PARD3,NFIA
1.960e-03	-6.23	synapse organization	biological process	GO:0050808	333	5	18204	49	NFIA,CTNND2,SPARCL1,GPM6A,NRXN1
2.021e-03	-6.20	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	49	FGFR3,PREX2
2.026e-03	-6.20	calcium ion binding	molecular function	GO:0005509	683	7	18094	48	NRXN1,PCDH9,PAMR1,RYR3,ITPR2,SPARCL1,MACF1
2.047e-03	-6.19	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	49	SLC1A2,SLC1A3
2.118e-03	-6.16	Muscle contraction	REACTOME pathways	R-HSA-397014	204	4	10285	28	ATP1A2,CAMK2G,RYR3,ITPR2
2.141e-03	-6.15	skeletal system development	biological process	GO:0001501	500	6	18204	49	BMPR1B,TRPS1,RANBP3L,SOX5,NFIA,FGFR3
2.152e-03	-6.14	extrinsic component of plasma membrane	cellular component	GO:0019897	100	3	19108	49	CDH20,CTNNA2,DTNA
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	DTNA,ABLIM1
2.185e-03	-6.13	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	50	PARD3,MSI2,TNIK,DTNA,ABLIM1,SLC1A3,MACF1
2.189e-03	-6.12	Pancreatic secretion	KEGG pathways	hsa04972	95	3	7161	20	ATP1A2,SLC4A4,ITPR2
2.189e-03	-6.12	Pancreatic secretion	KEGG pathways	ko04972	95	3	7161	20	ATP1A2,SLC4A4,ITPR2
2.214e-03	-6.11	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	49	SLC1A3,SLC1A2
2.282e-03	-6.08	transmembrane transporter activity	molecular function	GO:0022857	1110	9	18094	48	SFXN5,RYR3,SLC1A3,ITPR2,GPM6A,SLC4A4,ATP1A2,ATP13A4,SLC1A2
2.314e-03	-6.07	Ion channel transport	REACTOME pathways	R-HSA-983712	209	4	10285	28	CAMK2G,ATP13A4,ATP1A2,RYR3
2.345e-03	-6.06	LRRC7 (leucine rich repeat containing 7)	protein interactions	57554	28	2	19454	50	CTNND2,CAMK2G
2.467e-03	-6.00	response to alkaloid	biological process	GO:0043279	100	3	18204	49	RYR3,SLC1A3,SLC1A2
2.476e-03	-6.00	parathyroid	COSMIC cancer mutations	parathyroid	476	6	16828	49	PAMR1,MACF1,RYR3,GPC5,TRPS1,GPM6A
2.514e-03	-5.99	INSC (INSC spindle orientation adaptor protein)	protein interactions	387755	29	2	19454	50	PARD3,PARD3B
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	Sytl1 (synaptotagmin-like 1)	protein interactions	269589	1	1	19454	50	NRXN1
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	50	FGFR3
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	50	FGFR3
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.593e-03	-5.95	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	44	ATP1A2,ATP13A4
2.602e-03	-5.95	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	7	18094	48	SLC1A3,SLC1A2,ATP1A2,SLC4A4,RYR3,GPM6A,ITPR2
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A2,SLC1A3
2.673e-03	-5.92	ligand-gated calcium channel activity	molecular function	GO:0099604	29	2	18094	48	ITPR2,RYR3
2.692e-03	-5.92	negative regulation of collagen catabolic process	biological process	GO:0010711	1	1	18204	49	CST3
2.692e-03	-5.92	negative regulation of elastin catabolic process	biological process	GO:0060311	1	1	18204	49	CST3
2.692e-03	-5.92	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	49	ATP1A2
2.692e-03	-5.92	olfactory cortex development	biological process	GO:0021989	1	1	18204	49	ATP1A2
2.698e-03	-5.92	EN1 (engrailed homeobox 1)	protein interactions	2019	108	3	19454	50	NFIA,TRPS1,AHCYL2
2.700e-03	-5.91	ZNRF3_Znf_RING	interpro domains	IPR045903	1	1	18521	50	ZNRF3
2.700e-03	-5.91	TRPS1	interpro domains	IPR028440	1	1	18521	50	TRPS1
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.709e-03	-5.91	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	48	16828	49	LSAMP,FGFR3,PITPNC1,GLIS3,NPAS3,ATP1A2,CAMK2G,NKAIN3,RANBP3L,TRPS1,SLC1A3,BMPR1B,PTGDS,SLC1A2,PCDH9,ABLIM1,RFX4,PARD3B,GPM6A,RYR3,PARD3,FBXL7,NFIA,CTNND2,ZBTB20,PAMR1,PTPRZ1,NTM,AHCYL2,RORA,SLC4A4,NRXN1,MAML2,ITPR2,DTNA,CDH20,GPC5,ATP13A4,SOX5,HIF3A,CST3,TNIK,SPARCL1,MACF1,SFXN5,NHSL1,ZNRF3,PREX2
2.722e-03	-5.91	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	28	FGFR3
2.733e-03	-5.90	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	15	16828	49	TRPS1,NFIA,PARD3,PREX2,ZNRF3,NHSL1,RYR3,MACF1,SPARCL1,NPAS3,PARD3B,SLC1A3,CDH20,FGFR3,PAMR1
2.733e-03	-5.90	alveolar	COSMIC cancer mutations	alveolar	2414	15	16828	49	TRPS1,NFIA,PREX2,PARD3,RYR3,ZNRF3,NHSL1,MACF1,SPARCL1,NPAS3,PARD3B,CDH20,SLC1A3,PAMR1,FGFR3
2.809e-03	-5.87	caecum	COSMIC cancer mutations	caecum	14248	48	16828	49	SPARCL1,MACF1,SFXN5,NHSL1,ZNRF3,PREX2,CDH20,ATP13A4,GPC5,HIF3A,SOX5,CST3,TNIK,ITPR2,DTNA,PAMR1,NTM,AHCYL2,RORA,PTPRZ1,NRXN1,SLC4A4,MAML2,RYR3,PARD3,FBXL7,CTNND2,NFIA,ZBTB20,SLC1A3,SLC1A2,PTGDS,BMPR1B,PCDH9,ABLIM1,PARD3B,RFX4,GPM6A,ATP1A2,CAMK2G,NKAIN3,RANBP3L,TRPS1,LSAMP,FGFR3,PITPNC1,GLIS3,NPAS3
2.810e-03	-5.87	FGFR3_TM	pfam domains	PF21165	1	1	17795	50	FGFR3
2.810e-03	-5.87	MAML2_TAD	pfam domains	PF20804	1	1	17795	50	MAML2
2.834e-03	-5.87	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	49	NFIA,RORA,SOX5
2.857e-03	-5.86	catenin complex	cellular component	GO:0016342	31	2	19108	49	CTNNA2,CDH20
2.942e-03	-5.83	L-glutamate import	biological process	GO:0051938	30	2	18204	49	SLC1A2,SLC1A3
2.950e-03	-5.83	axonogenesis	biological process	GO:0007409	366	5	18204	49	BMPR1B,CTNNA2,PARD3,PTPRZ1,NRXN1
2.952e-03	-5.83	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	49	FGFR3,ITPR2,SLC1A3,NFIA,SOX5,ATP1A2,RYR3,SLC1A2,BMPR1B
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	TRPS1,NFIA,SOX5
2.993e-03	-5.81	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	8	19454	50	CAMK2G,NHSL1,ABLIM1,MACF1,PITPNC1,PARD3B,PARD3,FGFR3
3.041e-03	-5.80	-	gene3d domains	6.10.250.1740	1	1	14470	44	FGFR3
3.051e-03	-5.79	intracellularly ligand-gated monoatomic ion channel activity	molecular function	GO:0005217	31	2	18094	48	ITPR2,RYR3
3.057e-03	-5.79	NXPH2 (neurexophilin 2)	protein interactions	11249	32	2	19454	50	NRXN1,PCDH9
3.144e-03	-5.76	ORF3b (ORF3b protein)	protein interactions	1489670	114	3	19454	50	MACF1,ZBTB20,PCDH9
3.188e-03	-5.75	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	4	19454	50	CAMK2G,GPM6A,ITPR2,SOX5
3.222e-03	-5.74	SMAD7 (SMAD family member 7)	protein interactions	4092	115	3	19454	50	SOX5,BMPR1B,PARD3
3.224e-03	-5.74	human chr11p13	chromosome location	human chr11p13	44	2	26134	50	SLC1A2,PAMR1
3.315e-03	-5.71	cell-cell adhesion	biological process	GO:0098609	546	6	18204	49	PCDH9,CTNNA2,CDH20,NRXN1,SPARCL1,CTNND2
3.336e-03	-5.70	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	6	19454	50	PARD3,DTNA,TNIK,MACF1,ITPR2,PCDH9
3.344e-03	-5.70	centrosome localization	biological process	GO:0051642	32	2	18204	49	PARD3,PARD3B
3.344e-03	-5.70	positive regulation of ATP metabolic process	biological process	GO:1903580	32	2	18204	49	ZBTB20,SLC4A4
3.344e-03	-5.70	transepithelial transport	biological process	GO:0070633	32	2	18204	49	SLC1A3,SLC1A2
3.344e-03	-5.70	microtubule organizing center localization	biological process	GO:0061842	32	2	18204	49	PARD3B,PARD3
3.344e-03	-5.70	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	49	SOX5,BMPR1B
3.349e-03	-5.70	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	19	16828	49	ZBTB20,CTNND2,PREX2,PARD3,RYR3,NHSL1,MACF1,ATP1A2,SPARCL1,GPM6A,MAML2,ABLIM1,TNIK,PCDH9,SOX5,GPC5,SLC4A4,PTPRZ1,PAMR1
3.353e-03	-5.70	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	12	19454	50	PARD3,AHCYL2,BMPR1B,MACF1,PARD3B,MSI2,FGFR3,DTNA,ZBTB20,TRPS1,ABLIM1,NFIA
3.371e-03	-5.69	middle_third	COSMIC cancer mutations	middle_third	3533	19	16828	49	NHSL1,RYR3,MACF1,SPARCL1,ATP1A2,ZBTB20,CTNND2,PARD3,PREX2,PCDH9,SOX5,SLC4A4,GPC5,PTPRZ1,PAMR1,GPM6A,MAML2,ABLIM1,TNIK
3.415e-03	-5.68	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	50	ATP1A2,ATP13A4
3.430e-03	-5.68	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	49	FGFR3,PREX2
3.430e-03	-5.68	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	49	FGFR3,PREX2
3.468e-03	-5.66	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	31	16828	49	ATP1A2,ITPR2,RANBP3L,NKAIN3,SLC4A4,GLIS3,PAMR1,LSAMP,FGFR3,AHCYL2,RORA,MAML2,RYR3,NHSL1,SFXN5,MACF1,CTNND2,PREX2,PARD3,FBXL7,ATP13A4,SLC1A2,BMPR1B,GPC5,SOX5,PCDH9,SLC1A3,CDH20,RFX4,GPM6A,ABLIM1
3.476e-03	-5.66	connective tissue development	biological process	GO:0061448	232	4	18204	49	NFIA,BMPR1B,FGFR3,SOX5
3.482e-03	-5.66	cell adhesion molecule binding	molecular function	GO:0050839	560	6	18094	48	MACF1,NRXN1,CDH20,PTPRZ1,CTNND2,CTNNA2
3.486e-03	-5.66	dendrite development	biological process	GO:0016358	113	3	18204	49	PREX2,CTNND2,CTNNA2
3.621e-03	-5.62	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	41	16828	49	TRPS1,RANBP3L,DTNA,CAMK2G,ITPR2,ATP1A2,MAML2,NPAS3,GLIS3,SLC4A4,NRXN1,PTPRZ1,RORA,NTM,AHCYL2,LSAMP,FGFR3,PAMR1,ZBTB20,CTNND2,FBXL7,PARD3,PREX2,MSI2,NHSL1,SFXN5,ZNRF3,RYR3,MACF1,PARD3B,TNIK,CST3,SOX5,PCDH9,GPC5,BMPR1B,PTGDS,SLC1A2,ATP13A4,SLC1A3,CDH20
3.637e-03	-5.62	Cation_ATPase	pfam domains	PF13246	32	2	17795	50	ATP1A2,ATP13A4
3.649e-03	-5.61	TPRA1 (transmembrane protein adipocyte associated 1)	protein interactions	131601	35	2	19454	50	BMPR1B,ITPR2
3.653e-03	-5.61	response to endogenous stimulus	biological process	GO:0009719	1402	10	18204	49	SOX5,ATP1A2,RYR3,SLC1A2,PTGDS,BMPR1B,FGFR3,SLC1A3,ITPR2,NFIA
3.677e-03	-5.61	Glutamatergic synapse	KEGG pathways	hsa04724	114	3	7161	20	SLC1A2,SLC1A3,ITPR2
3.677e-03	-5.61	Glutamatergic synapse	KEGG pathways	ko04724	114	3	7161	20	ITPR2,SLC1A2,SLC1A3
3.680e-03	-5.60	synapse	cellular component	GO:0045202	1473	10	19108	49	SPARCL1,CTNND2,ATP1A2,GPM6A,SLC1A3,DTNA,TNIK,SLC1A2,PTPRZ1,NRXN1
3.688e-03	-5.60	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	3	18094	48	SLC1A2,SLC1A3,SLC4A4
3.688e-03	-5.60	calcium channel activity	molecular function	GO:0005262	117	3	18094	48	ITPR2,RYR3,GPM6A
3.792e-03	-5.57	PAS-like_dom_sf	interpro domains	IPR035965	34	2	18521	50	NPAS3,HIF3A
3.792e-03	-5.57	PAS	interpro domains	IPR000014	34	2	18521	50	NPAS3,HIF3A
3.857e-03	-5.56	SLC5A5 (solute carrier family 5 member 5)	protein interactions	6528	36	2	19454	50	SFXN5,CAMK2G
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A3,SLC1A2
3.908e-03	-5.54	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	8	16828	49	NPAS3,ABLIM1,PTGDS,ITPR2,ATP1A2,FGFR3,SPARCL1,PTPRZ1
3.936e-03	-5.54	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	21	16828	49	RORA,CDH20,SLC1A3,PTPRZ1,PAMR1,FGFR3,GLIS3,NPAS3,MAML2,PARD3B,MACF1,SPARCL1,CAMK2G,RYR3,ZNRF3,NHSL1,PREX2,PARD3,TRPS1,CTNND2,NFIA
4.014e-03	-5.52	DELLA	smart domains	SM01129	1	1	9717	39	MACF1
4.071e-03	-5.50	HPCA (hippocalcin)	protein interactions	3208	37	2	19454	50	GPM6A,CST3
4.127e-03	-5.49	striated muscle contraction	biological process	GO:0006941	120	3	18204	49	RYR3,ATP1A2,DTNA
4.183e-03	-5.48	monoatomic cation transport	biological process	GO:0006812	766	7	18204	49	SLC4A4,ATP13A4,GPM6A,ITPR2,SLC1A3,ATP1A2,RYR3
4.238e-03	-5.46	extraskeletal	COSMIC cancer mutations	extraskeletal	903	8	16828	49	PTGDS,NPAS3,ITPR2,ATP1A2,FGFR3,SPARCL1,ABLIM1,PTPRZ1
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP13A4,ATP1A2
4.442e-03	-5.42	PAS	smart domains	SM00091	25	2	9717	39	NPAS3,HIF3A
4.448e-03	-5.42	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	3	19454	50	ZBTB20,ITPR2,ABLIM1
4.451e-03	-5.41	positive regulation of purine nucleotide metabolic process	biological process	GO:1900544	37	2	18204	49	ZBTB20,SLC4A4
4.451e-03	-5.41	positive regulation of nucleotide metabolic process	biological process	GO:0045981	37	2	18204	49	ZBTB20,SLC4A4
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP13A4,ATP1A2
4.491e-03	-5.41	intracellular chemical homeostasis	biological process	GO:0055082	581	6	18204	49	RYR3,SLC1A3,ATP13A4,ATP1A2,ZBTB20,SLC4A4
4.607e-03	-5.38	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	27	16828	49	NRXN1,SLC4A4,GLIS3,FGFR3,PTPRZ1,TRPS1,CAMK2G,DTNA,ATP1A2,ITPR2,RFX4,PARD3B,GPM6A,ABLIM1,ATP13A4,GPC5,PCDH9,HIF3A,SLC1A3,CDH20,NFIA,ZBTB20,PREX2,PARD3,SFXN5,SPARCL1,MACF1
4.631e-03	-5.37	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	27	16828	49	SPARCL1,MACF1,SFXN5,PARD3,PREX2,NFIA,ZBTB20,CDH20,SLC1A3,GPC5,ATP13A4,HIF3A,PCDH9,ABLIM1,PARD3B,RFX4,GPM6A,ITPR2,ATP1A2,CAMK2G,DTNA,TRPS1,FGFR3,PTPRZ1,SLC4A4,NRXN1,GLIS3
4.691e-03	-5.36	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	49	SLC1A3,SLC1A2
4.744e-03	-5.35	DZIP1 (DAZ interacting zinc finger protein 1)	protein interactions	22873	40	2	19454	50	CAMK2G,PARD3
4.873e-03	-5.32	PDZ	pfam domains	PF00595	122	3	17795	50	PARD3,PREX2,PARD3B
4.936e-03	-5.31	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	49	SLC1A3,ATP1A2
4.977e-03	-5.30	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	21	16828	49	PAMR1,FGFR3,RORA,PTPRZ1,CDH20,SLC1A3,GLIS3,PARD3B,NPAS3,MAML2,SPARCL1,MACF1,CAMK2G,RYR3,NHSL1,ZNRF3,PREX2,PARD3,CTNND2,NFIA,TRPS1
5.042e-03	-5.29	testis	COSMIC cancer mutations	testis	733	7	16828	49	TNIK,MACF1,PREX2,FGFR3,TRPS1,CAMK2G,BMPR1B
5.049e-03	-5.29	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	3	19454	50	DTNA,ABLIM1,PARD3
5.123e-03	-5.27	cell development	biological process	GO:0048468	2236	13	18204	49	PREX2,SLC1A3,NTM,NRXN1,GPM6A,TNIK,CTNNA2,PARD3,RORA,PTPRZ1,CTNND2,MSI2,BMPR1B
5.127e-03	-5.27	EF-hand-dom_pair	interpro domains	IPR011992	258	4	18521	50	RYR3,DTNA,SPARCL1,MACF1
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.154e-03	-5.27	spindle	COSMIC cancer mutations	spindle	386	5	16828	49	FGFR3,PREX2,MACF1,CTNND2,PCDH9
5.157e-03	-5.27	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	8	16828	49	BMPR1B,CAMK2G,FGFR3,ATP1A2,ITPR2,MACF1,PREX2,TNIK
5.198e-03	-5.26	PAS	prosite domains	PS50112	30	2	12186	44	NPAS3,HIF3A
5.238e-03	-5.25	ion binding	molecular function	GO:0043167	6007	25	18094	48	ATP1A2,PITPNC1,ZNRF3,PCDH9,SLC1A3,NRXN1,PARD3,ZBTB20,MACF1,TNIK,RYR3,DTNA,ATP13A4,SLC1A2,TRPS1,ITPR2,PTGDS,PAMR1,BMPR1B,FGFR3,ABLIM1,GLIS3,SPARCL1,RORA,CAMK2G
5.251e-03	-5.25	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	49	DTNA,FGFR3,CDH20
5.288e-03	-5.24	axon development	biological process	GO:0061564	420	5	18204	49	PARD3,PTPRZ1,CTNNA2,BMPR1B,NRXN1
5.331e-03	-5.23	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	44	ATP13A4,ATP1A2
5.331e-03	-5.23	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	44	ATP1A2,ATP13A4
5.366e-03	-5.23	NFIB (nuclear factor I B)	protein interactions	4781	138	3	19454	50	TRPS1,NFIA,SOX5
5.376e-03	-5.23	Wnt receptor catabolic process	biological process	GO:0038018	2	1	18204	49	ZNRF3
5.376e-03	-5.23	mesenchymal cell differentiation involved in bone development	biological process	GO:1901706	2	1	18204	49	RANBP3L
5.376e-03	-5.23	regulation of elastin catabolic process	biological process	GO:0060310	2	1	18204	49	CST3
5.376e-03	-5.23	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	49	FGFR3
5.376e-03	-5.23	negative regulation of blood vessel remodeling	biological process	GO:0060313	2	1	18204	49	CST3
5.383e-03	-5.22	amino acid transport	biological process	GO:0006865	132	3	18204	49	SLC1A3,SLC1A2,SFXN5
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	ZNRF-3_ecto	interpro domains	IPR040700	2	1	18521	50	ZNRF3
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.404e-03	-5.22	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	28	16828	49	ABLIM1,GPM6A,PARD3B,RFX4,CDH20,SLC1A3,HIF3A,SOX5,GPC5,SLC1A2,FBXL7,PARD3,PREX2,ZBTB20,CTNND2,MACF1,NHSL1,SFXN5,RYR3,MAML2,NPAS3,PITPNC1,RORA,NTM,FGFR3,PAMR1,SLC4A4,TRPS1
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	FGFR3,LSAMP,NTM
5.482e-03	-5.21	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	31	16828	49	CST3,TNIK,ABLIM1,PARD3B,SLC1A3,PTGDS,ATP13A4,HIF3A,SOX5,PARD3,PREX2,CTNND2,ZBTB20,SPARCL1,MACF1,RYR3,MAML2,NPAS3,FGFR3,PAMR1,PTPRZ1,RORA,SLC4A4,NRXN1,GLIS3,NKAIN3,TRPS1,ITPR2,ATP1A2,CAMK2G,DTNA
5.492e-03	-5.20	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	4	18094	48	SFXN5,SLC4A4,SLC1A2,SLC1A3
5.497e-03	-5.20	regulation of sequestering of calcium ion	biological process	GO:0051282	133	3	18204	49	ATP1A2,ITPR2,RYR3
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A2,SLC1A3
5.612e-03	-5.18	ZNRF_3_ecto	pfam domains	PF18212	2	1	17795	50	ZNRF3
5.612e-03	-5.18	calcium ion transmembrane transporter activity	molecular function	GO:0015085	136	3	18094	48	ITPR2,GPM6A,RYR3
5.721e-03	-5.16	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	5	18204	49	SLC4A4,ATP13A4,RYR3,SLC1A3,ATP1A2
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	ATP1A2,RYR3,DTNA
5.802e-03	-5.15	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	4	16828	49	PCDH9,NPAS3,NFIA,GPC5
5.802e-03	-5.15	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	4	16828	49	NFIA,GPC5,NPAS3,PCDH9
5.885e-03	-5.14	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	4	16828	49	MACF1,PTPRZ1,FGFR3,GLIS3
5.968e-03	-5.12	small_intestine	COSMIC cancer mutations	small_intestine	250	4	16828	49	MACF1,TNIK,FGFR3,ZNRF3
5.997e-03	-5.12	FLOT1 (flotillin 1)	protein interactions	10211	453	5	19454	50	PARD3,ABLIM1,DTNA,SOX5,MACF1
5.998e-03	-5.12	transmembrane transport	biological process	GO:0055085	1264	9	18204	49	SLC4A4,SFXN5,ITPR2,ATP13A4,GPM6A,SLC1A3,RYR3,SLC1A2,ATP1A2
6.044e-03	-5.11	inorganic cation transmembrane transport	biological process	GO:0098662	618	6	18204	49	RYR3,ATP1A2,ITPR2,GPM6A,SLC1A3,SLC4A4
6.064e-03	-5.11	I-set	pfam domains	PF07679	132	3	17795	50	NTM,FGFR3,LSAMP
6.073e-03	-5.10	-	gene3d domains	6.20.350.10	2	1	14470	44	RYR3
6.073e-03	-5.10	Vinculin, Vh2 four-helix bundle	gene3d domains	1.20.120.810	2	1	14470	44	CTNNA2
6.087e-03	-5.10	phosphatidylinositol binding	molecular function	GO:0035091	276	4	18094	48	PITPNC1,PARD3B,PARD3,ITPR2
6.091e-03	-5.10	behavior	biological process	GO:0007610	619	6	18204	49	PTPRZ1,SLC1A2,NRXN1,SLC1A3,PREX2,ATP1A2
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	PARD3,CTNNA2,DTNA,GPM6A,SLC1A2,PCDH9
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	DTNA,CAMK2G,PARD3,CTNND2,MACF1
6.174e-03	-5.09	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	49	ATP1A2,SLC1A3,SLC1A2,SLC4A4
6.238e-03	-5.08	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	5	18204	49	ATP1A2,ATP13A4,RYR3,SLC1A3,SLC4A4
6.257e-03	-5.07	active transmembrane transporter activity	molecular function	GO:0022804	444	5	18094	48	ATP13A4,ATP1A2,SLC1A3,SLC1A2,SLC4A4
6.372e-03	-5.06	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	39	16828	49	MACF1,SPARCL1,MSI2,RYR3,NHSL1,SFXN5,FBXL7,PREX2,PARD3,CTNND2,NFIA,CDH20,SLC1A3,SOX5,HIF3A,PCDH9,SLC1A2,ATP13A4,GPC5,ABLIM1,TNIK,PARD3B,RFX4,ITPR2,ATP1A2,CAMK2G,NKAIN3,RANBP3L,RORA,AHCYL2,NTM,PTPRZ1,PAMR1,LSAMP,GLIS3,NRXN1,SLC4A4,NPAS3,MAML2
6.372e-03	-5.06	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	39	16828	49	CAMK2G,ATP1A2,ITPR2,RANBP3L,NKAIN3,NRXN1,SLC4A4,GLIS3,PAMR1,LSAMP,RORA,NTM,AHCYL2,PTPRZ1,NPAS3,MAML2,RYR3,SFXN5,NHSL1,MSI2,SPARCL1,MACF1,CTNND2,NFIA,PREX2,PARD3,FBXL7,SLC1A2,ATP13A4,GPC5,SOX5,PCDH9,HIF3A,SLC1A3,CDH20,RFX4,PARD3B,TNIK,ABLIM1
6.391e-03	-5.05	MOB4 (MOB family member 4, phocein)	protein interactions	25843	147	3	19454	50	CAMK2G,ABLIM1,TNIK
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	GPM6A,PTPRZ1
6.527e-03	-5.03	acidic amino acid transport	biological process	GO:0015800	45	2	18204	49	SLC1A3,SLC1A2
6.550e-03	-5.03	PAS domain	gene3d domains	3.30.450.20	40	2	14470	44	HIF3A,NPAS3
6.588e-03	-5.02	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	49	SLC1A2,SLC1A3,SLC4A4
6.624e-03	-5.02	metal ion transport	biological process	GO:0030001	630	6	18204	49	RYR3,ATP1A2,SLC1A3,ITPR2,GPM6A,SLC4A4
6.634e-03	-5.02	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	3	19454	50	SOX5,NFIA,TNIK
6.646e-03	-5.01	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	15	16828	49	MAML2,ATP13A4,NRXN1,PCDH9,SOX5,LSAMP,SLC1A3,PTPRZ1,CDH20,CTNND2,TRPS1,PARD3,PREX2,RYR3,ATP1A2
6.812e-03	-4.99	regulation of myelination	biological process	GO:0031641	46	2	18204	49	PARD3,PTPRZ1
6.870e-03	-4.98	uveal_tract	COSMIC cancer mutations	uveal_tract	587	6	16828	49	FGFR3,PREX2,MACF1,RANBP3L,CTNND2,PCDH9
6.932e-03	-4.97	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	15	16828	49	PARD3B,NPAS3,MAML2,GLIS3,FGFR3,RORA,PTPRZ1,CTNND2,NFIA,PREX2,RYR3,CAMK2G,ZNRF3,SPARCL1,MACF1
6.932e-03	-4.97	embryonal	COSMIC cancer mutations	embryonal	2659	15	16828	49	PARD3B,NPAS3,MAML2,GLIS3,FGFR3,RORA,PTPRZ1,CTNND2,NFIA,PREX2,CAMK2G,RYR3,ZNRF3,SPARCL1,MACF1
6.935e-03	-4.97	CATATPASE	prints domains	PR00119	35	2	5227	19	ATP13A4,ATP1A2
6.997e-03	-4.96	Wnt signaling pathway	biological process	GO:0016055	283	4	18204	49	MACF1,CTNND2,ZNRF3,TNIK
7.007e-03	-4.96	CAMK2B (calcium/calmodulin dependent protein kinase II beta)	protein interactions	816	152	3	19454	50	GPM6A,ITPR2,CAMK2G
7.009e-03	-4.96	response to organic cyclic compound	biological process	GO:0014070	843	7	18204	49	ITPR2,SLC1A3,RORA,RYR3,SLC1A2,PTGDS,ATP1A2
7.087e-03	-4.95	symporter activity	molecular function	GO:0015293	148	3	18094	48	SLC1A2,SLC1A3,SLC4A4
7.099e-03	-4.95	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	2	5310	18	CST3,SLC1A2
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	SOX5,TRPS1,NFIA
7.168e-03	-4.94	SLC-mediated transmembrane transport	REACTOME pathways	R-HSA-425407	287	4	10285	28	SLC1A2,SLC1A3,AHCYL2,SLC4A4
7.170e-03	-4.94	cell junction assembly	biological process	GO:0034329	285	4	18204	49	PARD3,CDH20,GPM6A,NRXN1
7.175e-03	-4.94	PDZ	interpro domains	IPR001478	146	3	18521	50	PARD3B,PARD3,PREX2
7.203e-03	-4.93	SFN (stratifin)	protein interactions	2810	671	6	19454	50	TNIK,ABLIM1,PARD3B,PARD3,NFIA,MACF1
7.209e-03	-4.93	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	44	SPARCL1
7.209e-03	-4.93	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	44	SPARCL1
7.224e-03	-4.93	lipid binding	molecular function	GO:0008289	861	7	18094	48	PTGDS,PARD3B,ATP1A2,PARD3,ITPR2,PITPNC1,RORA
7.272e-03	-4.92	Ig_3	pfam domains	PF13927	141	3	17795	50	NTM,FGFR3,LSAMP
7.426e-03	-4.90	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	44	ATP13A4,ATP1A2
7.493e-03	-4.89	cell surface	cellular component	GO:0009986	896	7	19108	49	SLC1A2,NRXN1,GPC5,FGFR3,SLC1A3,ATP1A2,SLC4A4
7.519e-03	-4.89	neuromuscular process	biological process	GO:0050905	149	3	18204	49	SLC1A3,NRXN1,CTNNA2
7.587e-03	-4.88	PDZ_sf	interpro domains	IPR036034	149	3	18521	50	PARD3,PARD3B,PREX2
7.592e-03	-4.88	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	49	ZNRF3,MACF1
7.592e-03	-4.88	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	49	ZNRF3,MACF1
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	NHSL1,MACF1
7.631e-03	-4.88	human chr8q23.3	chromosome location	human chr8q23.3	4	1	26134	50	TRPS1
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	NRXN1
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Hk2 (hexokinase 2)	protein interactions	25059	3	1	19454	50	PTGDS
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Lrrc7 (leucine rich repeat containing 7)	protein interactions	117284	3	1	19454	50	CAMK2G
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.700e-03	-4.87	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	49	FGFR3,PARD3,GPC5
7.750e-03	-4.86	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	21	16828	49	ABLIM1,GPM6A,RFX4,PTPRZ1,SLC1A3,FGFR3,GLIS3,PCDH9,HIF3A,SOX5,PREX2,PARD3,TRPS1,CTNND2,RANBP3L,MACF1,ATP1A2,RYR3,DTNA,ZNRF3,NHSL1
7.750e-03	-4.86	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	21	16828	49	NHSL1,ZNRF3,RYR3,DTNA,MACF1,ATP1A2,TRPS1,RANBP3L,CTNND2,PARD3,PREX2,PCDH9,SOX5,HIF3A,GLIS3,SLC1A3,PTPRZ1,FGFR3,GPM6A,RFX4,ABLIM1
7.761e-03	-4.86	C20 prostanoid biosynthesis	BIOCYC pathways	META_PWY66-374	7	1	902	1	PTGDS
7.761e-03	-4.86	C20 prostanoid biosynthesis	BIOCYC pathways	HUMAN_PWY66-374	7	1	902	1	PTGDS
7.923e-03	-4.84	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma	46	2	16828	49	RANBP3L,ITPR2
7.938e-03	-4.84	hydrolase activity, acting on carbon-sulfur bonds	molecular function	GO:0046508	3	1	18094	48	AHCYL2
7.938e-03	-4.84	adenosylhomocysteinase activity	molecular function	GO:0004013	3	1	18094	48	AHCYL2
7.938e-03	-4.84	prostaglandin-D synthase activity	molecular function	GO:0004667	3	1	18094	48	PTGDS
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.984e-03	-4.83	eye	COSMIC cancer mutations	eye	606	6	16828	49	RANBP3L,CTNND2,PCDH9,FGFR3,PREX2,MACF1
8.029e-03	-4.82	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	20	16828	49	PCDH9,ATP13A4,SLC1A2,SLC4A4,GPC5,RORA,AHCYL2,CDH20,PAMR1,FGFR3,PARD3B,RFX4,ABLIM1,MACF1,ATP1A2,ITPR2,TRPS1,CTNND2,PREX2,PARD3
8.054e-03	-4.82	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	49	ATP1A2
8.054e-03	-4.82	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	49	SLC1A2
8.054e-03	-4.82	radial glia guided migration of Purkinje cell	biological process	GO:0021942	3	1	18204	49	CTNNA2
8.054e-03	-4.82	cysteine transport	biological process	GO:0042883	3	1	18204	49	SLC1A2
8.054e-03	-4.82	neuroligin clustering involved in postsynaptic membrane assembly	biological process	GO:0097118	3	1	18204	49	NRXN1
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	TRPS1,NFIA,SOX5
8.078e-03	-4.82	MAML1-3	interpro domains	IPR046369	3	1	18521	50	MAML2
8.078e-03	-4.82	Vinculin_CS	interpro domains	IPR000633	3	1	18521	50	CTNNA2
8.078e-03	-4.82	Mastermind-like_N	interpro domains	IPR019082	3	1	18521	50	MAML2
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	SPRY2_RyR	interpro domains	IPR035764	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanodine_rcpt	interpro domains	IPR003032	3	1	18521	50	RYR3
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	Adenosylhomocyst_ase-like_sf	interpro domains	IPR042172	3	1	18521	50	AHCYL2
8.078e-03	-4.82	SPRY3_RyR	interpro domains	IPR035762	3	1	18521	50	RYR3
8.078e-03	-4.82	HIF_alpha-like	interpro domains	IPR021537	3	1	18521	50	HIF3A
8.078e-03	-4.82	Adenosylhomocysteinase-like	interpro domains	IPR000043	3	1	18521	50	AHCYL2
8.078e-03	-4.82	MAML_N_sf	interpro domains	IPR046370	3	1	18521	50	MAML2
8.078e-03	-4.82	Ado_hCys_hydrolase_NAD-bd	interpro domains	IPR015878	3	1	18521	50	AHCYL2
8.078e-03	-4.82	Ryan_recept	interpro domains	IPR013333	3	1	18521	50	RYR3
8.078e-03	-4.82	Ryanrecept_TM4-6	interpro domains	IPR009460	3	1	18521	50	RYR3
8.078e-03	-4.82	ROR_rcpt	interpro domains	IPR003079	3	1	18521	50	RORA
8.078e-03	-4.82	SPRY1_RyR	interpro domains	IPR035761	3	1	18521	50	RYR3
8.078e-03	-4.82	RYDR_Jsol	interpro domains	IPR048581	3	1	18521	50	RYR3
8.078e-03	-4.82	NR_DBD_ROR	interpro domains	IPR044101	3	1	18521	50	RORA
8.078e-03	-4.82	S-Ado-L-homoCys_hydrolase_CS	interpro domains	IPR020082	3	1	18521	50	AHCYL2
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.100e-03	-4.82	AFDN (afadin, adherens junction formation factor)	protein interactions	4301	309	4	19454	50	MACF1,PARD3,NRXN1,DTNA
8.194e-03	-4.80	small molecule binding	molecular function	GO:0036094	6197	25	18094	48	RORA,SPARCL1,ABLIM1,GLIS3,FGFR3,CAMK2G,TRPS1,ITPR2,ATP13A4,SLC1A2,BMPR1B,PTGDS,PAMR1,ZBTB20,MACF1,PARD3,DTNA,TNIK,RYR3,PITPNC1,ATP1A2,NRXN1,PCDH9,ZNRF3,SLC1A3
8.200e-03	-4.80	Oxytocin signaling pathway	KEGG pathways	ko04921	152	3	7161	20	CAMK2G,RYR3,ITPR2
8.200e-03	-4.80	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	3	7161	20	RYR3,CAMK2G,ITPR2
8.206e-03	-4.80	FOXF2 (forkhead box F2)	protein interactions	2295	53	2	19454	50	AHCYL2,ZBTB20
8.230e-03	-4.80	calcium-mediated signaling	biological process	GO:0019722	154	3	18204	49	ATP1A2,ITPR2,RYR3
8.320e-03	-4.79	neuromuscular process controlling balance	biological process	GO:0050885	51	2	18204	49	NRXN1,SLC1A3
8.392e-03	-4.78	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	28	SLC1A3,SLC1A2
8.406e-03	-4.78	MamL-1	pfam domains	PF09596	3	1	17795	50	MAML2
8.406e-03	-4.78	RyR	pfam domains	PF02026	3	1	17795	50	RYR3
8.406e-03	-4.78	Myelin_PLP	pfam domains	PF01275	3	1	17795	50	GPM6A
8.406e-03	-4.78	RYDR_Jsol	pfam domains	PF21119	3	1	17795	50	RYR3
8.406e-03	-4.78	HIF-1	pfam domains	PF11413	3	1	17795	50	HIF3A
8.406e-03	-4.78	RR_TM4-6	pfam domains	PF06459	3	1	17795	50	RYR3
8.406e-03	-4.78	SR_plectin_7	pfam domains	PF21097	3	1	17795	50	MACF1
8.406e-03	-4.78	AdoHcyase	pfam domains	PF05221	3	1	17795	50	AHCYL2
8.406e-03	-4.78	AdoHcyase_NAD	pfam domains	PF00670	3	1	17795	50	AHCYL2
8.458e-03	-4.77	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular function	GO:0000981	1355	9	18094	48	NPAS3,SOX5,RFX4,HIF3A,TRPS1,ZBTB20,RORA,NFIA,GLIS3
8.500e-03	-4.77	Hippo signaling pathway	KEGG pathways	ko04390	154	3	7161	20	PARD3,CTNNA2,BMPR1B
8.500e-03	-4.77	Hippo signaling pathway	KEGG pathways	hsa04390	154	3	7161	20	BMPR1B,PARD3,CTNNA2
8.525e-03	-4.76	retina development in camera-type eye	biological process	GO:0060041	156	3	18204	49	GPM6A,BMPR1B,NFIA
8.546e-03	-4.76	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	13	16828	49	SOX5,BMPR1B,SLC4A4,PTPRZ1,FGFR3,PARD3B,TNIK,CAMK2G,DTNA,ATP1A2,TRPS1,NFIA,PREX2
8.603e-03	-4.76	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-temporoparietal-glioma-astrocytoma_Grade_IV	48	2	16828	49	PARD3,RYR3
8.638e-03	-4.75	regulation of nucleotide catabolic process	biological process	GO:0030811	52	2	18204	49	SLC4A4,ZBTB20
8.638e-03	-4.75	regulation of purine nucleotide catabolic process	biological process	GO:0033121	52	2	18204	49	ZBTB20,SLC4A4
8.638e-03	-4.75	regulation of glycolytic process	biological process	GO:0006110	52	2	18204	49	ZBTB20,SLC4A4
8.638e-03	-4.75	OCLN (occludin)	protein interactions	100506658	495	5	19454	50	MACF1,TNIK,ABLIM1,DTNA,PARD3
8.711e-03	-4.74	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	49	FGFR3
8.711e-03	-4.74	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	49	FGFR3
8.711e-03	-4.74	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	49	FGFR3
8.712e-03	-4.74	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	48	ATP1A2,ATP13A4
8.771e-03	-4.74	EGR2 (early growth response 2)	protein interactions	1959	165	3	19454	50	NFIA,TRPS1,SOX5
8.814e-03	-4.73	SYN1 (synapsin I)	protein interactions	6853	55	2	19454	50	GPM6A,CAMK2G
8.962e-03	-4.71	neutral amino acid transport	biological process	GO:0015804	53	2	18204	49	SLC1A3,SLC1A2
8.979e-03	-4.71	monoatomic anion transport	biological process	GO:0006820	159	3	18204	49	SLC4A4,SLC1A3,SLC1A2
9.053e-03	-4.70	CTNNB1 (catenin beta 1)	protein interactions	1499	926	7	19454	50	NHSL1,DTNA,PARD3B,PTPRZ1,PARD3,CTNNA2,CTNND2
9.087e-03	-4.70	metal ion binding	molecular function	GO:0046872	4239	19	18094	48	TRPS1,ITPR2,ATP13A4,ATP1A2,SLC1A2,BMPR1B,NRXN1,PAMR1,ZNRF3,PCDH9,SLC1A3,ZBTB20,RORA,MACF1,SPARCL1,ABLIM1,GLIS3,DTNA,RYR3
9.095e-03	-4.70	-	gene3d domains	6.10.250.970	3	1	14470	44	MAML2
9.095e-03	-4.70	-	gene3d domains	1.10.490.160	3	1	14470	44	RYR3
9.095e-03	-4.70	-	gene3d domains	6.10.250.2510	3	1	14470	44	CTNNA2
9.095e-03	-4.70	Adenosylhomocysteinase-like	gene3d domains	3.40.50.1480	3	1	14470	44	AHCYL2
9.147e-03	-4.69	presynaptic membrane	cellular component	GO:0042734	168	3	19108	49	NRXN1,SLC1A2,GPM6A
9.191e-03	-4.69	EF-hand	gene3d domains	1.10.238.10	272	4	14470	44	RYR3,MACF1,SPARCL1,DTNA
9.428e-03	-4.66	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	10	16828	49	NPAS3,PARD3B,PREX2,PCDH9,GPC5,RYR3,DTNA,PTPRZ1,MACF1,FGFR3
9.442e-03	-4.66	NXPH3 (neurexophilin 3)	protein interactions	11248	57	2	19454	50	NRXN1,CTNNA2
9.565e-03	-4.65	export from cell	biological process	GO:0140352	485	5	18204	49	CAMK2G,SLC4A4,ATP1A2,NRXN1,PTGDS
9.616e-03	-4.64	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	48	16828	49	MAML2,SLC4A4,NRXN1,PTPRZ1,NTM,AHCYL2,RORA,PAMR1,DTNA,ITPR2,TNIK,HIF3A,SOX5,GPC5,ATP13A4,CDH20,PREX2,SFXN5,NHSL1,ZNRF3,MACF1,SPARCL1,NPAS3,GLIS3,PITPNC1,FGFR3,LSAMP,TRPS1,RANBP3L,NKAIN3,CAMK2G,ATP1A2,GPM6A,RFX4,PARD3B,ABLIM1,PCDH9,PTGDS,BMPR1B,SLC1A2,SLC1A3,ZBTB20,NFIA,CTNND2,FBXL7,PARD3,MSI2,RYR3
9.625e-03	-4.64	establishment or maintenance of epithelial cell apical/basal polarity	biological process	GO:0045197	55	2	18204	49	PARD3,PARD3B
9.625e-03	-4.64	response to cocaine	biological process	GO:0042220	55	2	18204	49	SLC1A2,SLC1A3
9.634e-03	-4.64	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	49	16828	49	MAML2,SLC4A4,NRXN1,PAMR1,PTPRZ1,RORA,AHCYL2,NTM,DTNA,ITPR2,CST3,TNIK,GPC5,ATP13A4,HIF3A,SOX5,CDH20,PREX2,NHSL1,SFXN5,ZNRF3,SPARCL1,MACF1,NPAS3,GLIS3,LSAMP,FGFR3,PITPNC1,RANBP3L,TRPS1,NKAIN3,CAMK2G,ATP1A2,RFX4,PARD3B,GPM6A,ABLIM1,BMPR1B,PTGDS,SLC1A2,PCDH9,SLC1A3,NFIA,CTNND2,ZBTB20,PARD3,FBXL7,RYR3,MSI2
9.704e-03	-4.64	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular function	GO:0000977	1385	9	18094	48	HIF3A,SOX5,RFX4,NPAS3,GLIS3,RORA,NFIA,ZBTB20,TRPS1
9.763e-03	-4.63	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	50	CAMK2G,MSI2
9.929e-03	-4.61	import across plasma membrane	biological process	GO:0098739	165	3	18204	49	ATP1A2,SLC1A2,SLC1A3
9.950e-03	-4.61	CAV1 (caveolin 1)	protein interactions	857	719	6	19454	50	MACF1,DTNA,TNIK,SLC1A3,AHCYL2,PARD3
9.964e-03	-4.61	release of sequestered calcium ion into cytosol	biological process	GO:0051209	56	2	18204	49	RYR3,ITPR2
1.002e-02	-4.60	Znf_NHR/GATA	interpro domains	IPR013088	56	2	18521	50	TRPS1,RORA
1.008e-02	-4.60	cellular homeostasis	biological process	GO:0019725	689	6	18204	49	SLC4A4,ATP13A4,SLC1A3,RYR3,ZBTB20,ATP1A2
1.022e-02	-4.58	extrinsic component of membrane	cellular component	GO:0019898	175	3	19108	49	DTNA,CTNNA2,CDH20
1.022e-02	-4.58	internode region of axon	cellular component	GO:0033269	4	1	19108	49	PARD3
1.024e-02	-4.58	Nme2 (NME/NM23 nucleoside diphosphate kinase 2)	protein interactions	18103	4	1	19454	50	RORA
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Ctbp2 (C-terminal binding protein 2)	protein interactions	13017	4	1	19454	50	TRPS1
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CALML4 (calmodulin like 4)	protein interactions	91860	4	1	19454	50	CAMK2G
1.026e-02	-4.58	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	27	16828	49	ATP1A2,ITPR2,CAMK2G,MAML2,NTM,RORA,PTPRZ1,PITPNC1,PAMR1,FGFR3,NRXN1,SLC4A4,PREX2,PARD3,ZBTB20,CTNND2,NFIA,MACF1,RYR3,ZNRF3,TNIK,ABLIM1,RFX4,SOX5,ATP13A4,GPC5,BMPR1B
1.026e-02	-4.58	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	27	16828	49	GPC5,BMPR1B,ATP13A4,SOX5,RFX4,TNIK,ABLIM1,ZNRF3,RYR3,MACF1,NFIA,CTNND2,ZBTB20,PARD3,PREX2,SLC4A4,NRXN1,FGFR3,PAMR1,PTPRZ1,PITPNC1,NTM,RORA,MAML2,CAMK2G,ATP1A2,ITPR2
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	TRPS1,NFIA,SOX5
1.031e-02	-4.57	visual behavior	biological process	GO:0007632	57	2	18204	49	SLC1A2,ATP1A2
1.031e-02	-4.57	negative regulation of sequestering of calcium ion	biological process	GO:0051283	57	2	18204	49	RYR3,ITPR2
1.034e-02	-4.57	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	7	19454	50	NFIA,CAMK2G,ATP13A4,SLC1A3,ZBTB20,CTNND2,TRPS1
1.041e-02	-4.56	-	gene3d domains	2.30.42.10	149	3	14470	44	PARD3,PARD3B,PREX2
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	DTNA,FGFR3
1.057e-02	-4.55	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	48	SFXN5
1.057e-02	-4.55	ryanodine-sensitive calcium-release channel activity	molecular function	GO:0005219	4	1	18094	48	RYR3
1.057e-02	-4.55	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	48	SFXN5
1.061e-02	-4.55	SYNPO (synaptopodin)	protein interactions	11346	177	3	19454	50	ZBTB20,CAMK2G,ABLIM1
1.070e-02	-4.54	chemical homeostasis	biological process	GO:0048878	914	7	18204	49	SLC1A3,ATP13A4,SLC4A4,RORA,ATP1A2,ZBTB20,RYR3
1.072e-02	-4.54	response to glycoside	biological process	GO:1903416	4	1	18204	49	ATP1A2
1.072e-02	-4.54	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	49	ATP1A2
1.072e-02	-4.54	regulation of collagen catabolic process	biological process	GO:0010710	4	1	18204	49	CST3
1.072e-02	-4.54	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	49	BMPR1B
1.072e-02	-4.54	negative regulation of germ cell proliferation	biological process	GO:1905937	4	1	18204	49	PTGDS
1.072e-02	-4.54	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	49	ATP1A2
1.072e-02	-4.54	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	49	SOX5
1.072e-02	-4.54	negative regulation of male germ cell proliferation	biological process	GO:2000255	4	1	18204	49	PTGDS
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA2
1.076e-02	-4.53	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI	interpro domains	IPR000647	4	1	18521	50	NFIA
1.076e-02	-4.53	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	1	18521	50	NFIA
1.076e-02	-4.53	Ca/CaM-dep_prot_kinase-assoc	interpro domains	IPR013543	4	1	18521	50	CAMK2G
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	1	18521	50	NFIA
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	CABP2 (calcium binding protein 2)	protein interactions	51475	61	2	19454	50	ITPR2,CAMK2G
1.079e-02	-4.53	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	44	GPM6A
1.079e-02	-4.53	VINCULIN_1	prosite domains	PS00663	3	1	12186	44	CTNNA2
1.079e-02	-4.53	ADOHCYASE_2	prosite domains	PS00739	3	1	12186	44	AHCYL2
1.079e-02	-4.53	ADOHCYASE_1	prosite domains	PS00738	3	1	12186	44	AHCYL2
1.079e-02	-4.53	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	44	GPM6A
1.087e-02	-4.52	RORNUCRECPTR	prints domains	PR01293	3	1	5227	19	RORA
1.087e-02	-4.52	RYANODINER	prints domains	PR00795	3	1	5227	19	RYR3
1.087e-02	-4.52	PGNDSYNTHASE	prints domains	PR01254	3	1	5227	19	PTGDS
1.087e-02	-4.52	MYELINPLP	prints domains	PR00214	3	1	5227	19	GPM6A
1.087e-02	-4.52	INSP3RECEPTR	prints domains	PR00779	3	1	5227	19	ITPR2
1.090e-02	-4.52	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	6	16828	49	FGFR3,PREX2,TNIK,BMPR1B,CAMK2G,TRPS1
1.098e-02	-4.51	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	49	16828	49	RANBP3L,TRPS1,NKAIN3,CAMK2G,ATP1A2,NPAS3,GLIS3,FGFR3,LSAMP,PITPNC1,CTNND2,NFIA,ZBTB20,PARD3,FBXL7,RYR3,MSI2,RFX4,PARD3B,GPM6A,ABLIM1,SLC1A2,PTGDS,BMPR1B,PCDH9,SLC1A3,DTNA,ITPR2,MAML2,NRXN1,SLC4A4,PAMR1,AHCYL2,RORA,NTM,PTPRZ1,PREX2,ZNRF3,NHSL1,SFXN5,SPARCL1,MACF1,CST3,TNIK,ATP13A4,GPC5,HIF3A,SOX5,CDH20
1.101e-02	-4.51	establishment or maintenance of apical/basal cell polarity	biological process	GO:0035088	59	2	18204	49	PARD3B,PARD3
1.101e-02	-4.51	endochondral bone morphogenesis	biological process	GO:0060350	59	2	18204	49	FGFR3,BMPR1B
1.101e-02	-4.51	establishment or maintenance of bipolar cell polarity	biological process	GO:0061245	59	2	18204	49	PARD3B,PARD3
1.104e-02	-4.51	EZR (ezrin)	protein interactions	7430	526	5	19454	50	MACF1,TNIK,ABLIM1,AHCYL2,DTNA
1.110e-02	-4.50	ARHGAP29 (Rho GTPase activating protein 29)	protein interactions	9411	62	2	19454	50	PARD3,CAMK2G
1.110e-02	-4.50	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	50	TRPS1,RORA,NFIA
1.119e-02	-4.49	AbLIM_anchor	pfam domains	PF16182	4	1	17795	50	ABLIM1
1.119e-02	-4.49	Spectrin_3	pfam domains	PF21019	4	1	17795	50	MACF1
1.119e-02	-4.49	CTF_NFI	pfam domains	PF00859	4	1	17795	50	NFIA
1.119e-02	-4.49	NHS	pfam domains	PF15273	4	1	17795	50	NHSL1
1.119e-02	-4.49	NKAIN	pfam domains	PF05640	4	1	17795	50	NKAIN3
1.119e-02	-4.49	P5-ATPase	pfam domains	PF12409	4	1	17795	50	ATP13A4
1.119e-02	-4.49	NfI_DNAbd_pre-N	pfam domains	PF10524	4	1	17795	50	NFIA
1.119e-02	-4.49	Spectrin_4	pfam domains	PF21020	4	1	17795	50	MACF1
1.119e-02	-4.49	Spectrin_2	pfam domains	PF18373	4	1	17795	50	MACF1
1.119e-02	-4.49	CaMKII_AD	pfam domains	PF08332	4	1	17795	50	CAMK2G
1.126e-02	-4.49	monoatomic cation homeostasis	biological process	GO:0055080	505	5	18204	49	RYR3,SLC1A3,ATP13A4,ATP1A2,SLC4A4
1.137e-02	-4.48	export across plasma membrane	biological process	GO:0140115	60	2	18204	49	ATP1A2,SLC4A4
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.156e-02	-4.46	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	4	16828	49	GLIS3,FGFR3,MACF1,PTPRZ1
1.160e-02	-4.46	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	49	FGFR3
1.160e-02	-4.46	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	49	PREX2
1.160e-02	-4.46	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	49	PREX2
1.160e-02	-4.46	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	49	FGFR3
1.160e-02	-4.46	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	49	FGFR3
1.160e-02	-4.46	inverted	COSMIC cancer mutations	inverted	4	1	16828	49	FGFR3
1.167e-02	-4.45	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	3	16828	49	MACF1,ITPR2,RYR3
1.178e-02	-4.44	cation binding	molecular function	GO:0043169	4341	19	18094	48	ATP1A2,ATP13A4,SLC1A2,ITPR2,TRPS1,PAMR1,SLC1A3,ZNRF3,PCDH9,NRXN1,BMPR1B,GLIS3,ABLIM1,RORA,MACF1,ZBTB20,SPARCL1,RYR3,DTNA
1.179e-02	-4.44	EVA1C (eva-1 homolog C)	protein interactions	59271	64	2	19454	50	BMPR1B,PCDH9
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	MAML2,DTNA
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	TRPS1,NFIA
1.184e-02	-4.44	cadherin binding	molecular function	GO:0045296	335	4	18094	48	CDH20,MACF1,CTNND2,CTNNA2
1.195e-02	-4.43	inorganic ion transmembrane transport	biological process	GO:0098660	715	6	18204	49	RYR3,ATP1A2,SLC4A4,SLC1A3,GPM6A,ITPR2
1.198e-02	-4.42	membrane	cellular component	GO:0016020	9220	32	19108	49	RYR3,SLC4A4,CTNNA2,SFXN5,ITPR2,CAMK2G,SLC1A2,ATP13A4,GPC5,PREX2,CTNND2,ZNRF3,PARD3,TNIK,PARD3B,NTM,MACF1,GPM6A,SLC1A3,BMPR1B,CDH20,LSAMP,FGFR3,NKAIN3,HIF3A,CST3,ATP1A2,DTNA,PTGDS,PCDH9,NRXN1,PTPRZ1
1.199e-02	-4.42	AdoHcyase	smart domains	SM00996	3	1	9717	39	AHCYL2
1.199e-02	-4.42	PLP	smart domains	SM00002	3	1	9717	39	GPM6A
1.199e-02	-4.42	AdoHcyase_NAD	smart domains	SM00997	3	1	9717	39	AHCYL2
1.199e-02	-4.42	MamL-1	smart domains	SM01275	3	1	9717	39	MAML2
1.211e-02	-4.41	-	gene3d domains	1.20.58.1060	4	1	14470	44	MACF1
1.211e-02	-4.41	regulation of carbohydrate catabolic process	biological process	GO:0043470	62	2	18204	49	SLC4A4,ZBTB20
1.218e-02	-4.41	monoatomic ion homeostasis	biological process	GO:0050801	515	5	18204	49	RYR3,SLC1A3,ATP13A4,ATP1A2,SLC4A4
1.221e-02	-4.41	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	7	16828	49	TRPS1,PREX2,TNIK,CAMK2G,BMPR1B,FGFR3,MACF1
1.240e-02	-4.39	DNA-binding transcription factor activity	molecular function	GO:0003700	1441	9	18094	48	TRPS1,RORA,NFIA,ZBTB20,GLIS3,NPAS3,SOX5,RFX4,HIF3A
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	SOX5,NFIA,TRPS1
1.249e-02	-4.38	back	COSMIC cancer mutations	back	310	4	16828	49	FGFR3,ATP1A2,PREX2,TNIK
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	MAML2,NFIA
1.254e-02	-4.38	Erythroid Transcription Factor GATA-1, subunit A	gene3d domains	3.30.50.10	56	2	14470	44	TRPS1,RORA
1.261e-02	-4.37	CDH1 (cadherin 1)	protein interactions	999	757	6	19454	50	NHSL1,ABLIM1,PARD3,CTNND2,CTNNA2,MACF1
1.265e-02	-4.37	brain development	biological process	GO:0007420	724	6	18204	49	ATP1A2,SLC1A2,CTNNA2,PCDH9,RFX4,RORA
1.266e-02	-4.37	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	3	16828	49	MACF1,ITPR2,RYR3
1.276e-02	-4.36	calcium- and calmodulin-dependent protein kinase complex	cellular component	GO:0005954	5	1	19108	49	CAMK2G
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.279e-02	-4.36	SYT13 (synaptotagmin 13)	protein interactions	57586	5	1	19454	50	NRXN1
1.279e-02	-4.36	RFX4 (regulatory factor X4)	protein interactions	5992	5	1	19454	50	RFX4
1.279e-02	-4.36	PTGER2 (prostaglandin E receptor 2)	protein interactions	5732	5	1	19454	50	PTGDS
1.279e-02	-4.36	ARSI (arylsulfatase family member I)	protein interactions	340075	5	1	19454	50	AHCYL2
1.279e-02	-4.36	CAMK2N2 (calcium/calmodulin dependent protein kinase II inhibitor 2)	protein interactions	94032	5	1	19454	50	CAMK2G
1.279e-02	-4.36	Hk3 (hexokinase 3)	protein interactions	25060	5	1	19454	50	PTGDS
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.296e-02	-4.35	regulation of Wnt signaling pathway	biological process	GO:0030111	339	4	18204	49	CTNND2,GPC5,ZNRF3,MACF1
1.302e-02	-4.34	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	18	ATP1A2,SLC1A3
1.302e-02	-4.34	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	48	16828	49	PTPRZ1,NTM,RORA,AHCYL2,PAMR1,SLC4A4,NRXN1,MAML2,ITPR2,CDH20,HIF3A,SOX5,GPC5,ATP13A4,TNIK,CST3,MACF1,SPARCL1,ZNRF3,NHSL1,SFXN5,PREX2,PITPNC1,LSAMP,FGFR3,GLIS3,NPAS3,ATP1A2,CAMK2G,NKAIN3,TRPS1,RANBP3L,SLC1A3,PCDH9,BMPR1B,PTGDS,SLC1A2,ABLIM1,GPM6A,RFX4,PARD3B,MSI2,RYR3,FBXL7,PARD3,ZBTB20,NFIA,CTNND2
1.310e-02	-4.34	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-medullomyoblastoma	485	5	16828	49	PCDH9,SLC4A4,ATP13A4,RYR3,LSAMP
1.310e-02	-4.34	medullomyoblastoma	COSMIC cancer mutations	medullomyoblastoma	485	5	16828	49	LSAMP,PCDH9,SLC4A4,ATP13A4,RYR3
1.312e-02	-4.33	regulation of carbohydrate metabolic process	biological process	GO:0006109	183	3	18204	49	RORA,SLC4A4,ZBTB20
1.317e-02	-4.33	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	48	SLC1A3,SLC1A2,SFXN5
1.317e-02	-4.33	upper_leg	COSMIC cancer mutations	upper_leg	880	7	16828	49	PREX2,NFIA,FGFR3,PAMR1,PCDH9,HIF3A,GLIS3
1.318e-02	-4.33	main axon	cellular component	GO:0044304	68	2	19108	49	PARD3,SLC1A2
1.319e-02	-4.33	endoplasmic reticulum	cellular component	GO:0005783	2051	11	19108	49	RYR3,SPARCL1,FGFR3,CAMK2G,ATP13A4,ITPR2,CST3,ATP1A2,NRXN1,AHCYL2,PTGDS
1.319e-02	-4.33	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	20	ITPR2,RYR3,CAMK2G
1.319e-02	-4.33	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	20	CAMK2G,RYR3,ITPR2
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.320e-02	-4.33	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	48	FGFR3
1.320e-02	-4.33	neuroligin family protein binding	molecular function	GO:0097109	5	1	18094	48	NRXN1
1.321e-02	-4.33	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	49	CAMK2G,ITPR2,TRPS1,RORA,PITPNC1,PTPRZ1,FGFR3,LSAMP,NPAS3,MAML2,MSI2,SPARCL1,CTNND2,FBXL7,PREX2,PARD3,HIF3A,SOX5,ATP13A4,BMPR1B,SLC1A3,TNIK,ABLIM1
1.321e-02	-4.33	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	49	TNIK,ABLIM1,NPAS3,MAML2,RORA,PTPRZ1,PITPNC1,SLC1A3,LSAMP,FGFR3,SOX5,HIF3A,ATP13A4,BMPR1B,FBXL7,PREX2,PARD3,TRPS1,CTNND2,ITPR2,SPARCL1,MSI2,CAMK2G
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A2,SLC1A3
1.328e-02	-4.32	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	10	18204	49	ZBTB20,SOX5,ATP1A2,BMPR1B,MACF1,NRXN1,SFXN5,PTPRZ1,PARD3,RORA
1.332e-02	-4.32	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	5	16828	49	MACF1,TNIK,FGFR3,BMPR1B,CAMK2G
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.336e-02	-4.32	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	48	SLC1A2,SLC1A3,SFXN5
1.339e-02	-4.31	citrate transport	biological process	GO:0015746	5	1	18204	49	SFXN5
1.339e-02	-4.31	gephyrin clustering involved in postsynaptic density assembly	biological process	GO:0097116	5	1	18204	49	NRXN1
1.339e-02	-4.31	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	49	SFXN5
1.339e-02	-4.31	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	49	BMPR1B
1.339e-02	-4.31	amygdala development	biological process	GO:0021764	5	1	18204	49	ATP1A2
1.343e-02	-4.31	Na/HCO3_transpt	interpro domains	IPR003024	5	1	18521	50	SLC4A4
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA2
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.344e-02	-4.31	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	18	CAMK2G,ITPR2,RYR3
1.347e-02	-4.31	signaling	biological process	GO:0023052	4968	21	18204	49	RYR3,SLC1A2,ZNRF3,BMPR1B,ITPR2,FGFR3,MACF1,RORA,PITPNC1,ATP1A2,SPARCL1,CTNND2,DTNA,SLC1A3,NRXN1,PREX2,NFIA,PARD3,TNIK,MAML2,CAMK2G
1.356e-02	-4.30	arm	COSMIC cancer mutations	arm	1331	9	16828	49	PARD3B,ZBTB20,NPAS3,TRPS1,SLC4A4,ATP1A2,FGFR3,NTM,MACF1
1.363e-02	-4.30	temporoparietal	COSMIC cancer mutations	temporoparietal	61	2	16828	49	RYR3,PARD3
1.364e-02	-4.29	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	49	SLC1A2,SLC1A3
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	MAML2,PAMR1,RORA,AHCYL2,NTM,PTPRZ1,NRXN1,SLC4A4,ITPR2,DTNA,CST3,TNIK,CDH20,ATP13A4,GPC5,SOX5,HIF3A,PREX2,SPARCL1,MACF1,SFXN5,ZNRF3,NHSL1,NPAS3,LSAMP,FGFR3,GLIS3,NKAIN3,RANBP3L,TRPS1,ATP1A2,CAMK2G,ABLIM1,PARD3B,RFX4,GPM6A,SLC1A3,SLC1A2,PTGDS,BMPR1B,PCDH9,PARD3,FBXL7,CTNND2,NFIA,ZBTB20,RYR3,MSI2
1.387e-02	-4.28	non_seminoma	COSMIC cancer mutations	non_seminoma	492	5	16828	49	BMPR1B,CAMK2G,TNIK,MACF1,FGFR3
1.397e-02	-4.27	IP_trans	pfam domains	PF02121	5	1	17795	50	PITPNC1
1.397e-02	-4.27	Vinculin	pfam domains	PF01044	5	1	17795	50	CTNNA2
1.397e-02	-4.27	SFXNs	pfam domains	PF03820	5	1	17795	50	SFXN5
1.397e-02	-4.27	FOLN	pfam domains	PF09289	5	1	17795	50	SPARCL1
1.397e-02	-4.27	Protocadherin	pfam domains	PF08374	5	1	17795	50	PCDH9
1.400e-02	-4.27	adenoma	COSMIC cancer mutations	adenoma	2873	15	16828	49	CDH20,PTPRZ1,FGFR3,SOX5,PCDH9,HIF3A,BMPR1B,GPC5,NPAS3,GPM6A,MACF1,RYR3,PARD3,ZBTB20,CTNND2
1.401e-02	-4.27	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	28	SLC1A2,CAMK2G,NRXN1,SLC1A3
1.407e-02	-4.26	RAB35 (RAB35, member RAS oncogene family)	protein interactions	11021	559	5	19454	50	DTNA,AHCYL2,SLC1A3,PARD3,MACF1
1.429e-02	-4.25	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	12	16828	49	TRPS1,NFIA,TNIK,PREX2,SOX5,CAMK2G,DTNA,BMPR1B,SLC4A4,PTPRZ1,ATP1A2,FGFR3
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	NFIA,TRPS1,SOX5
1.433e-02	-4.25	CAMK2D (calcium/calmodulin dependent protein kinase II delta)	protein interactions	817	198	3	19454	50	CAMK2G,FGFR3,ITPR2
1.437e-02	-4.24	CTF_NFI_1	prosite domains	PS00349	4	1	12186	44	NFIA
1.437e-02	-4.24	CTF_NFI_2	prosite domains	PS51080	4	1	12186	44	NFIA
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	TNIK,GPM6A
1.437e-02	-4.24	PAK6 (p21 (RAC1) activated kinase 6)	protein interactions	56924	71	2	19454	50	CAMK2G,AHCYL2
1.437e-02	-4.24	AKR7L (aldo-keto reductase family 7 like (gene/pseudogene))	protein interactions	246181	71	2	19454	50	MACF1,PARD3
1.446e-02	-4.24	ALPHACATENIN	prints domains	PR00805	4	1	5227	19	CTNNA2
1.448e-02	-4.24	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	49	FGFR3
1.448e-02	-4.24	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	49	PREX2
1.451e-02	-4.23	NTRK3 (neurotrophic receptor tyrosine kinase 3)	protein interactions	4916	367	4	19454	50	PARD3,AHCYL2,TNIK,ABLIM1
1.470e-02	-4.22	Long-term potentiation	KEGG pathways	ko04720	67	2	7161	20	ITPR2,CAMK2G
1.470e-02	-4.22	Long-term potentiation	KEGG pathways	hsa04720	67	2	7161	20	ITPR2,CAMK2G
1.475e-02	-4.22	PDZ	prosite domains	PS50106	143	3	12186	44	PARD3,PARD3B,PREX2
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	BMPR1B,PARD3B
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	GPM6A,TNIK
1.476e-02	-4.22	Ppp1cb (protein phosphatase 1 catalytic subunit beta)	protein interactions	19046	72	2	19454	50	PARD3,ABLIM1
1.480e-02	-4.21	EGF	pfam domains	PF00008	66	2	17795	50	NRXN1,PAMR1
1.485e-02	-4.21	cell communication	biological process	GO:0007154	5010	21	18204	49	PREX2,SLC1A3,NRXN1,MAML2,CAMK2G,TNIK,PARD3,NFIA,SPARCL1,ATP1A2,CTNND2,DTNA,PITPNC1,FGFR3,MACF1,ITPR2,RORA,ZNRF3,RYR3,SLC1A2,BMPR1B
1.489e-02	-4.21	transcription cis-regulatory region binding	molecular function	GO:0000976	1485	9	18094	48	TRPS1,ZBTB20,RORA,NFIA,GLIS3,NPAS3,SOX5,RFX4,HIF3A
1.501e-02	-4.20	transcription regulatory region nucleic acid binding	molecular function	GO:0001067	1487	9	18094	48	HIF3A,NPAS3,SOX5,RFX4,GLIS3,TRPS1,ZBTB20,RORA,NFIA
1.508e-02	-4.19	upper_back	COSMIC cancer mutations	upper_back	328	4	16828	49	GPC5,PARD3B,MACF1,FGFR3
1.511e-02	-4.19	-	gene3d domains	6.10.140.620	5	1	14470	44	CAMK2G
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	TRPS1,NFIA,SOX5
1.519e-02	-4.19	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	18	RYR3,ITPR2,CAMK2G
1.520e-02	-4.19	ORF3a (ORF3a protein)	protein interactions	43740569	789	6	19454	50	ZNRF3,PARD3,PARD3B,PCDH9,SLC4A4,BMPR1B
1.529e-02	-4.18	PAR polarity complex	cellular component	GO:0120157	6	1	19108	49	PARD3
1.532e-02	-4.18	CIBAR2 (CBY1 interacting BAR domain containing 2)	protein interactions	339145	6	1	19454	50	CAMK2G
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	50	FGFR3
1.532e-02	-4.18	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	50	FGFR3
1.532e-02	-4.18	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	50	FGFR3
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	SYTL3 (synaptotagmin like 3)	protein interactions	94120	6	1	19454	50	NRXN1
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	RSPO3 (R-spondin 3)	protein interactions	84870	6	1	19454	50	ZNRF3
1.547e-02	-4.17	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	49	ATP1A2,PCDH9
1.549e-02	-4.17	seminoma	COSMIC cancer mutations	seminoma	700	6	16828	49	CAMK2G,BMPR1B,TRPS1,PREX2,FGFR3,TNIK
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	SOX5,NFIA,TRPS1
1.554e-02	-4.16	bone development	biological process	GO:0060348	195	3	18204	49	BMPR1B,FGFR3,RANBP3L
1.572e-02	-4.15	UTRN (utrophin)	protein interactions	7402	205	3	19454	50	FGFR3,DTNA,PARD3
1.581e-02	-4.15	calcium-induced calcium release activity	molecular function	GO:0048763	6	1	18094	48	RYR3
1.581e-02	-4.15	sodium:bicarbonate symporter activity	molecular function	GO:0008510	6	1	18094	48	SLC4A4
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	ABLIM1,RFX4,PARD3B,GPM6A,SLC1A3,SLC1A2,BMPR1B,PTGDS,PCDH9,PARD3,FBXL7,CTNND2,NFIA,ZBTB20,RYR3,MSI2,NPAS3,FGFR3,LSAMP,GLIS3,NKAIN3,RANBP3L,TRPS1,ATP1A2,CAMK2G,CST3,TNIK,CDH20,ATP13A4,GPC5,SOX5,HIF3A,PREX2,SPARCL1,MACF1,ZNRF3,SFXN5,NHSL1,MAML2,PAMR1,NTM,AHCYL2,RORA,PTPRZ1,NRXN1,SLC4A4,ITPR2,DTNA
1.604e-02	-4.13	vocal learning	biological process	GO:0042297	6	1	18204	49	NRXN1
1.604e-02	-4.13	imitative learning	biological process	GO:0098596	6	1	18204	49	NRXN1
1.604e-02	-4.13	fused antrum stage	biological process	GO:0048165	6	1	18204	49	BMPR1B
1.604e-02	-4.13	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	49	SLC1A3
1.604e-02	-4.13	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	49	SOX5
1.604e-02	-4.13	negative regulation of extracellular matrix disassembly	biological process	GO:0010716	6	1	18204	49	CST3
1.604e-02	-4.13	postsynaptic density protein 95 clustering	biological process	GO:0097119	6	1	18204	49	NRXN1
1.609e-02	-4.13	Syndecan/Neurexin_dom	interpro domains	IPR027789	6	1	18521	50	NRXN1
1.609e-02	-4.13	Glypican_CS	interpro domains	IPR019803	6	1	18521	50	GPC5
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	Glypican	interpro domains	IPR001863	6	1	18521	50	GPC5
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	regulation of ATP metabolic process	biological process	GO:1903578	72	2	18204	49	SLC4A4,ZBTB20
1.613e-02	-4.13	MAGEA9 (MAGE family member A9)	protein interactions	4108	207	3	19454	50	NHSL1,CAMK2G,ITPR2
1.616e-02	-4.13	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	3	16828	49	GPC5,RYR3,PCDH9
1.629e-02	-4.12	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	4	19454	50	PARD3,FGFR3,MACF1,BMPR1B
1.641e-02	-4.11	Bile secretion	KEGG pathways	hsa04976	71	2	7161	20	SLC4A4,ATP1A2
1.641e-02	-4.11	Bile secretion	KEGG pathways	ko04976	71	2	7161	20	ATP1A2,SLC4A4
1.668e-02	-4.09	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	10	16828	49	PARD3B,CTNND2,ABLIM1,PREX2,DTNA,CDH20,PTPRZ1,RORA,MACF1,FGFR3
1.668e-02	-4.09	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	10	16828	49	PARD3B,CTNND2,PREX2,ABLIM1,DTNA,FGFR3,PTPRZ1,CDH20,MACF1,RORA
1.674e-02	-4.09	Plectin	pfam domains	PF00681	6	1	17795	50	MACF1
1.674e-02	-4.09	SH3_10	pfam domains	PF17902	6	1	17795	50	MACF1
1.674e-02	-4.09	Glypican	pfam domains	PF01153	6	1	17795	50	GPC5
1.674e-02	-4.09	EF-hand_2	pfam domains	PF09068	6	1	17795	50	DTNA
1.674e-02	-4.09	EF-hand_3	pfam domains	PF09069	6	1	17795	50	DTNA
1.674e-02	-4.09	Syndecan	pfam domains	PF01034	6	1	17795	50	NRXN1
1.674e-02	-4.09	GAS2	pfam domains	PF02187	6	1	17795	50	MACF1
1.685e-02	-4.08	Adherens junction	KEGG pathways	hsa04520	72	2	7161	20	CTNNA2,PARD3
1.685e-02	-4.08	Adherens junction	KEGG pathways	ko04520	72	2	7161	20	CTNNA2,PARD3
1.701e-02	-4.07	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	9	16828	49	CTNND2,PARD3B,RYR3,ATP13A4,PCDH9,ITPR2,ATP1A2,FGFR3,MACF1
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP13A4,ATP1A2
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.710e-02	-4.07	head development	biological process	GO:0060322	774	6	18204	49	SLC1A2,ATP1A2,RORA,RFX4,CTNNA2,PCDH9
1.716e-02	-4.07	MARCKS (myristoylated alanine rich protein kinase C substrate)	protein interactions	4082	588	5	19454	50	DTNA,AHCYL2,ABLIM1,SLC1A3,MACF1
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.735e-02	-4.05	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	49	PREX2
1.735e-02	-4.05	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	49	NHSL1
1.735e-02	-4.05	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	49	FGFR3
1.735e-02	-4.05	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	49	FGFR3
1.759e-02	-4.04	PRDM1 (PR/SET domain 1)	protein interactions	639	79	2	19454	50	NFIA,TRPS1
1.774e-02	-4.03	calcium ion transmembrane transport	biological process	GO:0070588	205	3	18204	49	GPM6A,ITPR2,RYR3
1.775e-02	-4.03	Thyroid hormone synthesis	KEGG pathways	ko04918	74	2	7161	20	ITPR2,ATP1A2
1.775e-02	-4.03	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	2	7161	20	ITPR2,ATP1A2
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Ahcyl1 (S-adenosylhomocysteine hydrolase-like 1)	protein interactions	229709	7	1	19454	50	AHCYL2
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	50	FGFR3
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.805e-02	-4.01	NAHCO3TRSPRT	prints domains	PR01232	5	1	5227	19	SLC4A4
1.805e-02	-4.01	PITRANSFER	prints domains	PR00391	5	1	5227	19	PITPNC1
1.811e-02	-4.01	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	44	MACF1
1.811e-02	-4.01	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	44	MACF1
1.821e-02	-4.01	SMAD binding	molecular function	GO:0046332	78	2	18094	48	BMPR1B,RANBP3L
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	RORA,ABLIM1,NKAIN3
1.827e-02	-4.00	BMP signaling pathway	biological process	GO:0030509	77	2	18204	49	NFIA,BMPR1B
1.827e-02	-4.00	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	49	ATP1A2,NRXN1
1.829e-02	-4.00	cellular process	biological process	GO:0009987	14996	46	18204	49	GLIS3,SOX5,DTNA,SLC1A3,NFIA,ABLIM1,GPC5,PTGDS,SLC1A2,NTM,PCDH9,RFX4,PREX2,CAMK2G,SFXN5,ZBTB20,RYR3,MACF1,RORA,SLC4A4,PTPRZ1,SPARCL1,CTNND2,PARD3B,FBXL7,NRXN1,ATP13A4,GPM6A,AHCYL2,NHSL1,BMPR1B,CDH20,HIF3A,ITPR2,ATP1A2,PITPNC1,MSI2,LSAMP,MAML2,TNIK,CTNNA2,PARD3,CST3,RANBP3L,ZNRF3,FGFR3
1.840e-02	-4.00	actin filament binding	molecular function	GO:0051015	211	3	18094	48	ABLIM1,CTNNA2,MACF1
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	calcium-dependent protein serine/threonine phosphatase activity	molecular function	GO:0004723	7	1	18094	48	CAMK2G
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	NFIA,TRPS1
1.865e-02	-3.98	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	4	18521	50	CAMK2G,BMPR1B,FGFR3,TNIK
1.869e-02	-3.98	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	1	18204	49	MAML2
1.869e-02	-3.98	glial cell fate specification	biological process	GO:0021780	7	1	18204	49	NFIA
1.869e-02	-3.98	S-adenosylmethionine cycle	biological process	GO:0033353	7	1	18204	49	AHCYL2
1.869e-02	-3.98	negative regulation of non-canonical Wnt signaling pathway	biological process	GO:2000051	7	1	18204	49	ZNRF3
1.869e-02	-3.98	observational learning	biological process	GO:0098597	7	1	18204	49	NRXN1
1.869e-02	-3.98	cellular response to magnesium ion	biological process	GO:0071286	7	1	18204	49	RYR3
1.869e-02	-3.98	negative regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:0034316	7	1	18204	49	CTNNA2
1.869e-02	-3.98	regulation of male germ cell proliferation	biological process	GO:2000254	7	1	18204	49	PTGDS
1.869e-02	-3.98	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	49	PTPRZ1
1.872e-02	-3.98	dicarboxylic acid transport	biological process	GO:0006835	78	2	18204	49	SLC1A3,SLC1A2
1.872e-02	-3.98	positive regulation of carbohydrate metabolic process	biological process	GO:0045913	78	2	18204	49	SLC4A4,ZBTB20
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA2
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP13A4,ATP1A2
1.889e-02	-3.97	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	47	16828	49	DTNA,ITPR2,SLC4A4,NRXN1,PAMR1,PTPRZ1,RORA,AHCYL2,NTM,MAML2,ZNRF3,SFXN5,NHSL1,SPARCL1,MACF1,PREX2,GPC5,ATP13A4,HIF3A,SOX5,CDH20,TNIK,CAMK2G,ATP1A2,RANBP3L,TRPS1,NKAIN3,GLIS3,LSAMP,FGFR3,PITPNC1,NPAS3,RYR3,MSI2,NFIA,CTNND2,ZBTB20,PARD3,FBXL7,BMPR1B,SLC1A2,PCDH9,SLC1A3,PARD3B,RFX4,GPM6A,ABLIM1
1.891e-02	-3.97	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	28	FGFR3
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.902e-02	-3.96	sequence-specific double-stranded DNA binding	molecular function	GO:1990837	1547	9	18094	48	GLIS3,TRPS1,ZBTB20,RORA,NFIA,HIF3A,RFX4,SOX5,NPAS3
1.914e-02	-3.96	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	73	2	16828	49	FGFR3,MACF1
1.922e-02	-3.95	prostate	COSMIC cancer mutations	prostate	13883	46	16828	49	FBXL7,PARD3,ZBTB20,NFIA,CTNND2,MSI2,RYR3,ABLIM1,GPM6A,PARD3B,RFX4,SLC1A3,PCDH9,BMPR1B,SLC1A2,NKAIN3,TRPS1,RANBP3L,ATP1A2,NPAS3,PITPNC1,FGFR3,LSAMP,GLIS3,PREX2,MACF1,SPARCL1,SFXN5,NHSL1,ZNRF3,TNIK,CDH20,SOX5,HIF3A,GPC5,ATP13A4,ITPR2,DTNA,MAML2,PTPRZ1,NTM,RORA,AHCYL2,PAMR1,SLC4A4,NRXN1
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	NFIA,TRPS1
1.930e-02	-3.95	SYT1 (synaptotagmin 1)	protein interactions	6857	83	2	19454	50	NRXN1,GPM6A
1.930e-02	-3.95	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	50	GPM6A,FGFR3
1.938e-02	-3.94	PDZ	smart domains	SM00228	143	3	9717	39	PARD3B,PREX2,PARD3
1.943e-02	-3.94	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	PREX2,PARD3,SLC1A2,ATP13A4,GPC5,ITPR2,MACF1
1.943e-02	-3.94	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	49	ITPR2,MACF1,SLC1A2,ATP13A4,GPC5,PREX2,PARD3
1.951e-02	-3.94	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	50	SPARCL1
1.951e-02	-3.94	TGF_beta_GS	pfam domains	PF08515	7	1	17795	50	BMPR1B
1.954e-02	-3.94	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	2	18094	48	BMPR1B,FGFR3
1.964e-02	-3.93	oligodendroglioma_Grade_II	COSMIC cancer mutations	oligodendroglioma_Grade_II	74	2	16828	49	FGFR3,MACF1
1.976e-02	-3.92	CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2)	protein interactions	830	403	4	19454	50	MACF1,ITPR2,ABLIM1,CAMK2G
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	GPM6A,MACF1,ABLIM1
1.990e-02	-3.92	Endochondral Ossification	WikiPathways	WP474	65	2	5310	18	SOX5,FGFR3
2.002e-02	-3.91	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	7	19454	50	ABLIM1,NHSL1,CAMK2G,PITPNC1,MACF1,PARD3B,PARD3
2.004e-02	-3.91	somatodendritic compartment	cellular component	GO:0036477	842	6	19108	49	SLC1A3,GPM6A,BMPR1B,ATP1A2,NRXN1,CTNND2
2.008e-02	-3.91	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	50	NFIA,TRPS1,SOX5
2.009e-02	-3.91	adult locomotory behavior	biological process	GO:0008344	81	2	18204	49	PREX2,ATP1A2
2.020e-02	-3.90	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	8	19454	50	NFIA,MACF1,SOX5,ITPR2,LSAMP,MSI2,TRPS1,GLIS3
2.021e-02	-3.90	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	49	FGFR3
2.021e-02	-3.90	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	49	FGFR3
2.021e-02	-3.90	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	49	PREX2
2.021e-02	-3.90	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	49	FGFR3
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.038e-02	-3.89	PTGER1 (prostaglandin E receptor 1)	protein interactions	5731	8	1	19454	50	PTGDS
2.043e-02	-3.89	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	6	16828	49	PREX2,PARD3,FGFR3,MACF1,CDH20,ATP13A4
2.044e-02	-3.89	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	25	16828	49	ZBTB20,CTNND2,PREX2,PARD3,RYR3,MACF1,SPARCL1,ABLIM1,CST3,SOX5,ATP13A4,SLC1A3,NKAIN3,DTNA,CAMK2G,ITPR2,ATP1A2,NPAS3,MAML2,GLIS3,SLC4A4,RORA,PTPRZ1,PAMR1,FGFR3
2.058e-02	-3.88	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	3	10285	28	SLC1A2,CAMK2G,SLC1A3
2.063e-02	-3.88	EGLN1 (egl-9 family hypoxia inducible factor 1)	protein interactions	54583	86	2	19454	50	FGFR3,HIF3A
2.101e-02	-3.86	EF_hand_dom	interpro domains	IPR002048	218	3	18521	50	MACF1,SPARCL1,RYR3
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.105e-02	-3.86	glutamatergic synapse	cellular component	GO:0098978	412	4	19108	49	GPM6A,SPARCL1,TNIK,SLC1A2
2.106e-02	-3.86	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	49	PREX2,MACF1,CTNND2,PCDH9
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	TRPS1,NFIA
2.108e-02	-3.86	Kctd5 (potassium channel tetramerisation domain containing 5)	protein interactions	69259	87	2	19454	50	TRPS1,SLC1A3
2.108e-02	-3.86	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	2	19454	50	SOX5,NFIA
2.109e-02	-3.86	glial cell differentiation	biological process	GO:0010001	219	3	18204	49	PTPRZ1,PARD3,NFIA
2.123e-02	-3.85	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	49	PARD3,FBXL7,CTNND2,NFIA,ZBTB20,RYR3,MSI2,ABLIM1,PARD3B,GPM6A,SLC1A3,SLC1A2,PTGDS,BMPR1B,PCDH9,NKAIN3,RANBP3L,TRPS1,ATP1A2,CAMK2G,NPAS3,FGFR3,LSAMP,PITPNC1,GLIS3,PREX2,SPARCL1,MACF1,ZNRF3,NHSL1,SFXN5,TNIK,CDH20,ATP13A4,GPC5,HIF3A,SOX5,ITPR2,DTNA,MAML2,PAMR1,AHCYL2,RORA,PTPRZ1,NRXN1,SLC4A4
2.123e-02	-3.85	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	49	SLC1A3,PCDH9,SLC1A2,BMPR1B,PTGDS,ABLIM1,GPM6A,PARD3B,MSI2,RYR3,FBXL7,PARD3,ZBTB20,CTNND2,NFIA,PITPNC1,FGFR3,LSAMP,GLIS3,NPAS3,ATP1A2,CAMK2G,NKAIN3,TRPS1,RANBP3L,CDH20,SOX5,HIF3A,ATP13A4,GPC5,TNIK,MACF1,SPARCL1,NHSL1,SFXN5,ZNRF3,PREX2,RORA,AHCYL2,PTPRZ1,PAMR1,NRXN1,SLC4A4,MAML2,ITPR2,DTNA
2.125e-02	-3.85	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	44	ATP13A4,ATP1A2
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	ATP1A2,PARD3,TNIK
2.130e-02	-3.85	leg	COSMIC cancer mutations	leg	969	7	16828	49	PTPRZ1,NTM,FGFR3,HIF3A,ZBTB20,SLC4A4,ATP13A4
2.134e-02	-3.85	regulation of synapse structural plasticity	biological process	GO:0051823	8	1	18204	49	CTNNA2
2.134e-02	-3.85	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	49	ATP1A2
2.134e-02	-3.85	cell proliferation in external granule layer	biological process	GO:0021924	8	1	18204	49	RORA
2.134e-02	-3.85	cell proliferation in hindbrain	biological process	GO:0021534	8	1	18204	49	RORA
2.134e-02	-3.85	cerebellar granule cell precursor proliferation	biological process	GO:0021930	8	1	18204	49	RORA
2.134e-02	-3.85	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	49	SLC1A3
2.134e-02	-3.85	regulation of germ cell proliferation	biological process	GO:1905936	8	1	18204	49	PTGDS
2.134e-02	-3.85	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	49	NRXN1,SLC1A3,ATP1A2
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	RFX-like	interpro domains	IPR039779	8	1	18521	50	RFX4
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.147e-02	-3.84	GLYPICAN	prosite domains	PS01207	6	1	12186	44	GPC5
2.147e-02	-3.84	GAR	prosite domains	PS51460	6	1	12186	44	MACF1
2.151e-02	-3.84	L-amino acid transport	biological process	GO:0015807	84	2	18204	49	SLC1A2,SLC1A3
2.151e-02	-3.84	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	49	ATP1A2,NKAIN3
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	BMPR1B,TNIK
2.153e-02	-3.84	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	2	7161	20	CAMK2G,ITPR2
2.153e-02	-3.84	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	2	7161	20	CAMK2G,ITPR2
2.158e-02	-3.84	Release of Hh-Np from the secreting cell	REACTOME pathways	R-HSA-5362798	8	1	10285	28	GPC5
2.162e-02	-3.83	ACTIVIN2R	prints domains	PR00653	6	1	5227	19	BMPR1B
2.165e-02	-3.83	establishment of localization	biological process	GO:0051234	3887	17	18204	49	PITPNC1,PARD3B,ATP1A2,NRXN1,SLC1A3,ATP13A4,GPM6A,PARD3,CAMK2G,SFXN5,RYR3,PTGDS,SLC1A2,RANBP3L,ITPR2,MACF1,SLC4A4
2.168e-02	-3.83	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	9	16828	49	FGFR3,MACF1,PTPRZ1,CDH20,NRXN1,RYR3,PREX2,CTNND2,RFX4
2.168e-02	-3.83	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	9	16828	49	FGFR3,PTPRZ1,CDH20,MACF1,RYR3,NRXN1,PREX2,RFX4,CTNND2
2.185e-02	-3.82	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	9	16828	49	RYR3,NRXN1,SLC4A4,GPC5,LSAMP,CTNND2,TRPS1,PARD3,TNIK
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	TRPS1,NFIA
2.199e-02	-3.82	PLEKHA2 (pleckstrin homology domain containing A2)	protein interactions	59339	89	2	19454	50	AHCYL2,DTNA
2.201e-02	-3.82	organic anion transport	biological process	GO:0015711	398	4	18204	49	SLC1A2,SLC1A3,SLC4A4,SFXN5
2.224e-02	-3.81	HMG20A (high mobility group 20A)	protein interactions	10363	234	3	19454	50	NFIA,SOX5,DTNA
2.226e-02	-3.80	VHP	pfam domains	PF02209	8	1	17795	50	ABLIM1
2.229e-02	-3.80	cell-cell signaling	biological process	GO:0007267	822	6	18204	49	SLC1A2,DTNA,CAMK2G,SLC1A3,NRXN1,FGFR3
2.232e-02	-3.80	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	5	16828	49	FBXL7,TRPS1,SLC4A4,RYR3,CTNND2
2.246e-02	-3.80	FGFR1OP2 (FGFR1 oncogene partner 2)	protein interactions	26127	90	2	19454	50	TNIK,CAMK2G
2.249e-02	-3.79	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	3	19454	50	MACF1,PARD3,DTNA
2.262e-02	-3.79	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	5	16828	49	FBXL7,SLC4A4,CTNND2,RYR3,TRPS1
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.290e-02	-3.78	CAMK2N1 (calcium/calmodulin dependent protein kinase II inhibitor 1)	protein interactions	55450	9	1	19454	50	CAMK2G
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	50	FGFR3
2.290e-02	-3.78	Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae))	protein interactions	209584	9	1	19454	50	CTNNA2
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	FGFR3
2.292e-02	-3.78	FOXI1 (forkhead box I1)	protein interactions	2299	91	2	19454	50	NFIA,TRPS1
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.303e-02	-3.77	Insulin secretion	KEGG pathways	hsa04911	85	2	7161	20	ATP1A2,CAMK2G
2.306e-02	-3.77	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	49	PREX2
2.306e-02	-3.77	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	49	FGFR3
2.306e-02	-3.77	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	49	FGFR3
2.306e-02	-3.77	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	49	FGFR3
2.306e-02	-3.77	junctional	COSMIC cancer mutations	junctional	8	1	16828	49	FGFR3
2.309e-02	-3.77	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	49	MAML2,CAMK2G,RYR3,TNIK,FGFR3
2.318e-02	-3.76	skin-leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-leg-malignant_melanoma-superficial_spreading	210	3	16828	49	NTM,SLC4A4,ATP13A4
2.320e-02	-3.76	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	4	FGFR3
2.325e-02	-3.76	forearm	COSMIC cancer mutations	forearm	81	2	16828	49	PREX2,FGFR3
2.339e-02	-3.76	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	50	FGFR3,DTNA
2.339e-02	-3.76	SOX9 (SRY-box transcription factor 9)	protein interactions	6662	92	2	19454	50	TRPS1,NFIA
2.339e-02	-3.76	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	50	FGFR3,TNIK
2.341e-02	-3.75	skeletal system morphogenesis	biological process	GO:0048705	228	3	18204	49	BMPR1B,SOX5,FGFR3
2.385e-02	-3.74	GAS2	smart domains	SM00243	6	1	9717	39	MACF1
2.385e-02	-3.74	forebrain development	biological process	GO:0030900	408	4	18204	49	RFX4,PCDH9,SLC1A2,ATP1A2
2.387e-02	-3.74	MPDZ (multiple PDZ domain crumbs cell polarity complex component)	protein interactions	8777	93	2	19454	50	PARD3,FGFR3
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	ABLIM1,BMPR1B
2.397e-02	-3.73	cyclooxygenase pathway	biological process	GO:0019371	9	1	18204	49	PTGDS
2.397e-02	-3.73	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0014808	9	1	18204	49	RYR3
2.397e-02	-3.73	positive regulation of synapse maturation	biological process	GO:0090129	9	1	18204	49	NRXN1
2.397e-02	-3.73	hindbrain radial glia guided cell migration	biological process	GO:0021932	9	1	18204	49	CTNNA2
2.397e-02	-3.73	negative regulation of actin nucleation	biological process	GO:0051126	9	1	18204	49	CTNNA2
2.397e-02	-3.73	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	49	ATP1A2
2.397e-02	-3.73	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	49	ATP13A4
2.401e-02	-3.73	-	gene3d domains	2.80.10.50	79	2	14470	44	RYR3,ITPR2
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.404e-02	-3.73	Prot_inh_cystat_CS	interpro domains	IPR018073	9	1	18521	50	CST3
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Band3_cytoplasmic_dom	interpro domains	IPR013769	9	1	18521	50	SLC4A4
2.404e-02	-3.73	DNA-bd_RFX	interpro domains	IPR003150	9	1	18521	50	RFX4
2.407e-02	-3.73	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	44	ABLIM1
2.411e-02	-3.73	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	49	ITPR2,RYR3,PREX2,ATP1A2,FGFR3,TNIK
2.430e-02	-3.72	protein binding	molecular function	GO:0005515	13983	43	18094	48	CAMK2G,HIF3A,RANBP3L,SOX5,GLIS3,ABLIM1,GPM6A,FGFR3,RORA,SPARCL1,PTGDS,BMPR1B,RFX4,CTNNA2,MAML2,SLC1A2,SLC4A4,GPC5,ITPR2,TRPS1,RYR3,TNIK,MSI2,NPAS3,DTNA,CDH20,PARD3B,CTNND2,MACF1,NFIA,NTM,LSAMP,CST3,PARD3,SFXN5,FBXL7,SLC1A3,ZNRF3,NRXN1,PTPRZ1,AHCYL2,ATP1A2,PITPNC1
2.435e-02	-3.72	FOXP4 (forkhead box P4)	protein interactions	116113	94	2	19454	50	SOX5,NFIA
2.435e-02	-3.72	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	2	19454	50	ABLIM1,TNIK
2.435e-02	-3.72	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	2	19454	50	FGFR3,CAMK2G
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	NFIA,SOX5
2.437e-02	-3.71	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	20	16828	49	TNIK,MAML2,FGFR3,PITPNC1,PTPRZ1,RORA,BMPR1B,NRXN1,HIF3A,PCDH9,SOX5,PREX2,FBXL7,CTNND2,TRPS1,ITPR2,MACF1,ZNRF3,CAMK2G,MSI2
2.437e-02	-3.71	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	20	16828	49	MAML2,TNIK,SOX5,HIF3A,PCDH9,BMPR1B,NRXN1,PTPRZ1,PITPNC1,RORA,FGFR3,TRPS1,CTNND2,FBXL7,PREX2,MSI2,ZNRF3,CAMK2G,MACF1,ITPR2
2.446e-02	-3.71	regulation of purine nucleotide metabolic process	biological process	GO:1900542	90	2	18204	49	SLC4A4,ZBTB20
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.468e-02	-3.70	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	6	16828	49	TNIK,FGFR3,SOX5,BMPR1B,CAMK2G,CTNND2
2.468e-02	-3.70	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	6	16828	49	TNIK,FGFR3,SOX5,BMPR1B,CAMK2G,CTNND2
2.483e-02	-3.70	STRIP1 (striatin interacting protein 1)	protein interactions	85369	95	2	19454	50	TNIK,CAMK2G
2.496e-02	-3.69	regulation of nucleotide metabolic process	biological process	GO:0006140	91	2	18204	49	ZBTB20,SLC4A4
2.496e-02	-3.69	response to BMP	biological process	GO:0071772	91	2	18204	49	NFIA,BMPR1B
2.496e-02	-3.69	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	49	NFIA,BMPR1B
2.501e-02	-3.69	GS	prosite domains	PS51256	7	1	12186	44	BMPR1B
2.501e-02	-3.69	RFX_DNA_binding	pfam domains	PF02257	9	1	17795	50	RFX4
2.501e-02	-3.69	Activin_recp	pfam domains	PF01064	9	1	17795	50	BMPR1B
2.501e-02	-3.69	Band_3_cyto	pfam domains	PF07565	9	1	17795	50	SLC4A4
2.504e-02	-3.69	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	4	16828	49	MAML2,CAMK2G,TNIK,FGFR3
2.504e-02	-3.69	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	4	16828	49	TNIK,FGFR3,MAML2,CAMK2G
2.504e-02	-3.69	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	4	16828	49	TNIK,FGFR3,MAML2,CAMK2G
2.504e-02	-3.69	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	4	16828	49	FGFR3,TNIK,CAMK2G,MAML2
2.504e-02	-3.69	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	4	16828	49	FGFR3,TNIK,CAMK2G,MAML2
2.519e-02	-3.68	chemical synaptic transmission	biological process	GO:0007268	415	4	18204	49	SLC1A3,SLC1A2,NRXN1,DTNA
2.519e-02	-3.68	anterograde trans-synaptic signaling	biological process	GO:0098916	415	4	18204	49	SLC1A2,NRXN1,SLC1A3,DTNA
2.529e-02	-3.68	TRIM67 (tripartite motif containing 67)	protein interactions	440730	4804	19	19454	50	PITPNC1,MACF1,SLC4A4,CST3,PARD3,PTPRZ1,LSAMP,AHCYL2,ATP1A2,NTM,ITPR2,CAMK2G,SLC1A3,CTNNA2,GPM6A,CTNND2,MSI2,TNIK,DTNA
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.547e-02	-3.67	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	7	19454	50	PARD3,PARD3B,PITPNC1,MACF1,CAMK2G,ABLIM1,NHSL1
2.573e-02	-3.66	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	28	NTM,LSAMP
2.581e-02	-3.66	PLCB3 (phospholipase C beta 3)	protein interactions	5331	97	2	19454	50	PARD3,CAMK2G
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	NFIA,SOX5,TNIK
2.586e-02	-3.66	parotid	COSMIC cancer mutations	parotid	578	5	16828	49	TNIK,FGFR3,MAML2,RYR3,CAMK2G
2.591e-02	-3.65	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	compound	COSMIC cancer mutations	compound	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	PREX2
2.591e-02	-3.65	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	49	FGFR3
2.591e-02	-3.65	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	49	FGFR3
2.591e-02	-3.65	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	49	FGFR3
2.591e-02	-3.65	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	49	FGFR3
2.612e-02	-3.65	MYO1B (myosin IB)	protein interactions	4430	249	3	19454	50	PARD3,CAMK2G,FGFR3
2.616e-02	-3.64	muscle contraction	biological process	GO:0006936	238	3	18204	49	RYR3,ATP1A2,DTNA
2.621e-02	-3.64	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	44	16828	49	SPARCL1,MACF1,ZNRF3,NHSL1,SFXN5,PREX2,CDH20,ATP13A4,GPC5,SOX5,HIF3A,CST3,TNIK,ITPR2,PAMR1,AHCYL2,NTM,RORA,PTPRZ1,NRXN1,SLC4A4,MAML2,RYR3,PARD3,FBXL7,CTNND2,ZBTB20,SLC1A3,SLC1A2,PTGDS,BMPR1B,PCDH9,RFX4,PARD3B,GPM6A,ATP1A2,CAMK2G,NKAIN3,RANBP3L,TRPS1,FGFR3,LSAMP,GLIS3,NPAS3
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	PARD3,FGFR3
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	LSAMP,GPM6A
2.646e-02	-3.63	human chr2p16.3	chromosome location	human chr2p16.3	14	1	26134	50	NRXN1
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.654e-02	-3.63	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	49	PARD3B,SLC4A4,ITPR2,PREX2,FGFR3
2.660e-02	-3.63	postsynaptic density assembly	biological process	GO:0097107	10	1	18204	49	NRXN1
2.660e-02	-3.63	neuronal action potential propagation	biological process	GO:0019227	10	1	18204	49	ATP1A2
2.660e-02	-3.63	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological process	GO:1903514	10	1	18204	49	RYR3
2.660e-02	-3.63	action potential propagation	biological process	GO:0098870	10	1	18204	49	ATP1A2
2.660e-02	-3.63	postsynaptic membrane assembly	biological process	GO:0097104	10	1	18204	49	NRXN1
2.660e-02	-3.63	learned vocalization behavior or vocal learning	biological process	GO:0098598	10	1	18204	49	NRXN1
2.660e-02	-3.63	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	49	SOX5
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	FGFR3,NTM,LSAMP
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.668e-02	-3.62	HCO3_transpt-like_TM_dom	interpro domains	IPR011531	10	1	18521	50	SLC4A4
2.668e-02	-3.62	PTrfase/Anion_transptr	interpro domains	IPR016152	10	1	18521	50	SLC4A4
2.668e-02	-3.62	HCO3_transpt_euk	interpro domains	IPR003020	10	1	18521	50	SLC4A4
2.670e-02	-3.62	GnRH signaling pathway	KEGG pathways	hsa04912	92	2	7161	20	ITPR2,CAMK2G
2.670e-02	-3.62	GnRH signaling pathway	KEGG pathways	ko04912	92	2	7161	20	ITPR2,CAMK2G
2.680e-02	-3.62	ZFHX3 (zinc finger homeobox 3)	protein interactions	463	99	2	19454	50	SOX5,TRPS1
2.680e-02	-3.62	TNKS (tankyrase)	protein interactions	8658	99	2	19454	50	TNIK,PCDH9
2.683e-02	-3.62	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	48	ATP1A2,ATP13A4
2.690e-02	-3.62	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	28	FGFR3
2.693e-02	-3.61	CRX (cone-rod homeobox)	protein interactions	1406	252	3	19454	50	SOX5,TRPS1,NFIA
2.698e-02	-3.61	double-stranded DNA binding	molecular function	GO:0003690	1643	9	18094	48	NFIA,RORA,ZBTB20,TRPS1,GLIS3,SOX5,RFX4,NPAS3,HIF3A
2.704e-02	-3.61	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	49	RYR3,ITPR2
2.720e-02	-3.60	mucosal	COSMIC cancer mutations	mucosal	2009	11	16828	49	ABLIM1,RORA,FGFR3,PCDH9,ATP13A4,BMPR1B,PREX2,PARD3,CTNND2,ATP1A2,SPARCL1
2.720e-02	-3.60	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	11	16828	49	ABLIM1,PREX2,PARD3,CTNND2,RORA,ATP1A2,SPARCL1,FGFR3,PCDH9,ATP13A4,BMPR1B
2.731e-02	-3.60	APBA1 (amyloid beta precursor protein binding family A member 1)	protein interactions	320	100	2	19454	50	ABLIM1,NRXN1
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	ATP1A2,GPM6A
2.737e-02	-3.60	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	49	PCDH9,CTNND2,BMPR1B
2.760e-02	-3.59	Methionine degradation	KEGG pathways	M00035	10	1	7161	20	AHCYL2
2.760e-02	-3.59	Methionine degradation	KEGG pathways	hsa_M00035	10	1	7161	20	AHCYL2
2.775e-02	-3.58	HCO3_cotransp	pfam domains	PF00955	10	1	17795	50	SLC4A4
2.775e-02	-3.58	PAS_3	pfam domains	PF08447	10	1	17795	50	NPAS3
2.776e-02	-3.58	DYNLL2 (dynein light chain LC8-type 2)	protein interactions	140735	255	3	19454	50	TRPS1,NFIA,NHSL1
2.777e-02	-3.58	GS	smart domains	SM00467	7	1	9717	39	BMPR1B
2.777e-02	-3.58	PLEC	smart domains	SM00250	7	1	9717	39	MACF1
2.781e-02	-3.58	CLEC4A (C-type lectin domain family 4 member A)	protein interactions	50856	101	2	19454	50	FGFR3,CTNNA2
2.784e-02	-3.58	sequence-specific DNA binding	molecular function	GO:0043565	1652	9	18094	48	GLIS3,ZBTB20,RORA,NFIA,TRPS1,HIF3A,SOX5,NPAS3,RFX4
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.792e-02	-3.58	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	50	FGFR3
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	ITPR2
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.792e-02	-3.58	SYTL1 (synaptotagmin like 1)	protein interactions	84958	11	1	19454	50	NRXN1
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	PTGDR (prostaglandin D2 receptor)	protein interactions	5729	11	1	19454	50	PTGDS
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.810e-02	-3.57	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	49	SLC1A3,SLC1A2
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	KRTAP6-1 (keratin associated protein 6-1)	protein interactions	337966	102	2	19454	50	CAMK2G,GLIS3
2.842e-02	-3.56	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	49	NRXN1,SLC1A3,SLC1A2,DTNA
2.842e-02	-3.56	response to wounding	biological process	GO:0009611	431	4	18204	49	NFIA,MACF1,SLC1A3,SLC1A2
2.847e-02	-3.56	regulation of synapse organization	biological process	GO:0050807	246	3	18204	49	GPM6A,NRXN1,CTNNA2
2.849e-02	-3.56	transcription regulator activity	molecular function	GO:0140110	1937	10	18094	48	MAML2,GLIS3,ZBTB20,RORA,NFIA,TRPS1,HIF3A,SOX5,NPAS3,RFX4
2.853e-02	-3.56	HP	prosite domains	PS51089	8	1	12186	44	ABLIM1
2.853e-02	-3.56	GATA_ZN_FINGER_1	prosite domains	PS00344	8	1	12186	44	TRPS1
2.865e-02	-3.55	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	46	16828	49	PARD3B,RFX4,GPM6A,ABLIM1,BMPR1B,PTGDS,SLC1A2,PCDH9,SLC1A3,NFIA,CTNND2,ZBTB20,PARD3,FBXL7,RYR3,MSI2,NPAS3,GLIS3,FGFR3,LSAMP,PITPNC1,RANBP3L,TRPS1,CAMK2G,ATP1A2,TNIK,GPC5,ATP13A4,HIF3A,SOX5,CDH20,PREX2,ZNRF3,SFXN5,SPARCL1,MACF1,MAML2,SLC4A4,NRXN1,PAMR1,PTPRZ1,RORA,AHCYL2,NTM,DTNA,ITPR2
2.873e-02	-3.55	GATAZNFINGER	prints domains	PR00619	8	1	5227	19	TRPS1
2.873e-02	-3.55	LIPOCALIN	prints domains	PR00179	8	1	5227	19	PTGDS
2.875e-02	-3.55	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	49	FGFR3
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	PREX2
2.875e-02	-3.55	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	49	FGFR3
2.875e-02	-3.55	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	49	FGFR3
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	FGFR3
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.880e-02	-3.55	acetylcholine receptor binding	molecular function	GO:0033130	11	1	18094	48	NRXN1
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	BMPR1B,GPM6A
2.885e-02	-3.55	inorganic ion homeostasis	biological process	GO:0098771	433	4	18204	49	ATP13A4,SLC1A3,RYR3,ATP1A2
2.889e-02	-3.54	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	3	19454	50	DTNA,PARD3,PARD3B
2.889e-02	-3.54	Circadian entrainment	KEGG pathways	ko04713	96	2	7161	20	CAMK2G,RYR3
2.889e-02	-3.54	Circadian entrainment	KEGG pathways	hsa04713	96	2	7161	20	CAMK2G,RYR3
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A2,SLC1A3
2.917e-02	-3.53	bone morphogenesis	biological process	GO:0060349	99	2	18204	49	FGFR3,BMPR1B
2.922e-02	-3.53	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	49	ATP1A2
2.922e-02	-3.53	polyamine transport	biological process	GO:0015846	11	1	18204	49	ATP13A4
2.922e-02	-3.53	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	49	BMPR1B
2.922e-02	-3.53	cellular response to caffeine	biological process	GO:0071313	11	1	18204	49	RYR3
2.922e-02	-3.53	lactone metabolic process	biological process	GO:1901334	11	1	18204	49	ATP1A2
2.922e-02	-3.53	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	49	ATP1A2
2.931e-02	-3.53	RanBP1-like	interpro domains	IPR045255	11	1	18521	50	RANBP3L
2.931e-02	-3.53	Ran_bind_dom	interpro domains	IPR000156	11	1	18521	50	RANBP3L
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	ABLIM1,SPARCL1
2.945e-02	-3.53	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	2	7161	20	CAMK2G,ITPR2
2.945e-02	-3.53	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	2	7161	20	ITPR2,CAMK2G
2.946e-02	-3.52	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	3	19454	50	DTNA,PARD3,MACF1
2.988e-02	-3.51	BEND3 (BEN domain containing 3)	protein interactions	57673	105	2	19454	50	TNIK,TRPS1
2.988e-02	-3.51	ANP32E (acidic nuclear phosphoprotein 32 family member E)	protein interactions	81611	105	2	19454	50	AHCYL2,PARD3
2.997e-02	-3.51	calcium ion transport	biological process	GO:0006816	251	3	18204	49	RYR3,GPM6A,ITPR2
3.000e-02	-3.51	Helical hairpin bin	gene3d domains	1.10.287.570	10	1	14470	44	SLC4A4
3.027e-02	-3.50	regulation of synapse structure or activity	biological process	GO:0050803	252	3	18204	49	GPM6A,NRXN1,CTNNA2
3.030e-02	-3.50	abdomen	COSMIC cancer mutations	abdomen	603	5	16828	49	PREX2,ITPR2,FGFR3,CTNND2,RANBP3L
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	LGR5 (leucine rich repeat containing G protein-coupled receptor 5)	protein interactions	8549	12	1	19454	50	ZNRF3
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	Pard6b (par-6 family cell polarity regulator beta)	protein interactions	58220	12	1	19454	50	PARD3
3.042e-02	-3.49	CA4 (carbonic anhydrase 4)	protein interactions	762	12	1	19454	50	SLC4A4
3.049e-02	-3.49	PAS_11	pfam domains	PF14598	11	1	17795	50	HIF3A
3.049e-02	-3.49	Ran_BP1	pfam domains	PF00638	11	1	17795	50	RANBP3L
3.063e-02	-3.49	spleen	COSMIC cancer mutations	spleen	408	4	16828	49	PARD3B,NTM,TNIK,PTPRZ1
3.092e-02	-3.48	Circadian rythm related genes	WikiPathways	WP3594	207	3	5310	18	RORA,PTGDS,CST3
3.101e-02	-3.47	regulation of neuron projection development	biological process	GO:0010975	443	4	18204	49	CAMK2G,TNIK,CTNNA2,MACF1
3.125e-02	-3.47	regulation of biological process	biological process	GO:0050789	12079	39	18204	49	MACF1,FGFR3,PTPRZ1,NPAS3,SLC4A4,RORA,RANBP3L,ZNRF3,ZBTB20,RYR3,PREX2,CTNNA2,SFXN5,TNIK,CAMK2G,MAML2,PARD3,CST3,ATP1A2,PITPNC1,RFX4,MSI2,HIF3A,ITPR2,GPC5,NKAIN3,SLC1A2,PTGDS,BMPR1B,GPM6A,SLC1A3,NRXN1,NFIA,DTNA,CTNND2,GLIS3,SOX5,SPARCL1,TRPS1
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	TRPS1,NFIA
3.147e-02	-3.46	FKBP1A (FKBP prolyl isomerase 1A)	protein interactions	2280	108	2	19454	50	RYR3,MSI2
3.147e-02	-3.46	CAMKV (CaM kinase like vesicle associated)	protein interactions	79012	108	2	19454	50	GPM6A,AHCYL2
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	NHSL1,ABLIM1,CAMK2G,MACF1
3.155e-02	-3.46	regulation of multicellular organismal process	biological process	GO:0051239	3113	14	18204	49	ZBTB20,PTGDS,BMPR1B,MACF1,RORA,PTPRZ1,ATP1A2,SOX5,TRPS1,NRXN1,CAMK2G,SFXN5,CST3,PARD3
3.158e-02	-3.46	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	PREX2
3.158e-02	-3.46	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	49	FGFR3
3.158e-02	-3.46	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	49	FGFR3
3.158e-02	-3.46	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	49	FGFR3
3.158e-02	-3.46	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	49	PREX2
3.167e-02	-3.45	VHP	smart domains	SM00153	8	1	9717	39	ABLIM1
3.179e-02	-3.45	NAD+ Signalling and Aging	SMPDB pathways	SMP0084271	11	1	1369	4	RORA
3.184e-02	-3.45	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	49	SLC1A2
3.184e-02	-3.45	regulation of blood vessel remodeling	biological process	GO:0060312	12	1	18204	49	CST3
3.184e-02	-3.45	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	49	BMPR1B
3.184e-02	-3.45	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	49	BMPR1B
3.184e-02	-3.45	negative regulation of collagen metabolic process	biological process	GO:0010713	12	1	18204	49	CST3
3.193e-02	-3.44	Lipocalin_CS	interpro domains	IPR022272	12	1	18521	50	PTGDS
3.193e-02	-3.44	Lipocalin	interpro domains	IPR002345	12	1	18521	50	PTGDS
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.193e-02	-3.44	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	1	18521	50	NFIA
3.204e-02	-3.44	CYSTATIN	prosite domains	PS00287	9	1	12186	44	CST3
3.204e-02	-3.44	RFX_DBD	prosite domains	PS51526	9	1	12186	44	RFX4
3.207e-02	-3.44	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	48	16828	49	MAML2,NRXN1,SLC4A4,PAMR1,NTM,AHCYL2,RORA,PTPRZ1,DTNA,ITPR2,CST3,TNIK,ATP13A4,GPC5,SOX5,HIF3A,CDH20,PREX2,SFXN5,ZNRF3,NHSL1,SPARCL1,MACF1,NPAS3,GLIS3,LSAMP,FGFR3,PITPNC1,RANBP3L,TRPS1,CAMK2G,ATP1A2,PARD3B,RFX4,GPM6A,ABLIM1,SLC1A2,BMPR1B,PTGDS,PCDH9,SLC1A3,CTNND2,NFIA,ZBTB20,PARD3,FBXL7,RYR3,MSI2
3.207e-02	-3.44	bile_duct	COSMIC cancer mutations	bile_duct	15095	48	16828	49	TRPS1,RANBP3L,ATP1A2,CAMK2G,NPAS3,PITPNC1,FGFR3,LSAMP,GLIS3,FBXL7,PARD3,ZBTB20,NFIA,CTNND2,MSI2,RYR3,ABLIM1,GPM6A,RFX4,PARD3B,SLC1A3,PCDH9,PTGDS,BMPR1B,SLC1A2,ITPR2,DTNA,MAML2,PTPRZ1,NTM,AHCYL2,RORA,PAMR1,SLC4A4,NRXN1,PREX2,MACF1,SPARCL1,ZNRF3,SFXN5,NHSL1,TNIK,CST3,CDH20,SOX5,HIF3A,GPC5,ATP13A4
3.220e-02	-3.44	VEGFR2 mediated cell proliferation	REACTOME pathways	R-HSA-5218921	258	3	10285	28	FGFR3,ITPR2,CAMK2G
3.220e-02	-3.44	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	REACTOME pathways	R-HSA-3656253	12	1	10285	28	GPC5
3.220e-02	-3.44	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	28	FGFR3
3.220e-02	-3.44	Regulation of gene expression by Hypoxia-inducible Factor	REACTOME pathways	R-HSA-1234158	12	1	10285	28	HIF3A
3.220e-02	-3.44	Defective EXT2 causes exostoses 2	REACTOME pathways	R-HSA-3656237	12	1	10285	28	GPC5
3.220e-02	-3.44	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	28	FGFR3
3.231e-02	-3.43	Glucagon signaling pathway	KEGG pathways	ko04922	102	2	7161	20	ITPR2,CAMK2G
3.231e-02	-3.43	Glucagon signaling pathway	KEGG pathways	hsa04922	102	2	7161	20	ITPR2,CAMK2G
3.250e-02	-3.43	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular function	GO:0001227	263	3	18094	48	ZBTB20,TRPS1,GLIS3
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	BMPR1B,PARD3B
3.271e-02	-3.42	RDX (radixin)	protein interactions	5962	272	3	19454	50	ABLIM1,FGFR3,MACF1
3.275e-02	-3.42	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	5	18204	49	CTNNA2,TNIK,CAMK2G,GPM6A,MACF1
3.276e-02	-3.42	steroid binding	molecular function	GO:0005496	107	2	18094	48	RORA,ATP1A2
3.276e-02	-3.42	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	42	16828	49	ABLIM1,TNIK,RFX4,PARD3B,GPM6A,SLC1A3,CDH20,BMPR1B,GPC5,ATP13A4,SLC1A2,SOX5,PCDH9,HIF3A,PARD3,PREX2,FBXL7,NFIA,CTNND2,ZBTB20,SPARCL1,MACF1,NHSL1,SFXN5,RYR3,MAML2,NPAS3,LSAMP,FGFR3,PAMR1,PTPRZ1,PITPNC1,NTM,AHCYL2,RORA,NRXN1,GLIS3,NKAIN3,RANBP3L,TRPS1,ATP1A2,ITPR2
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	NRXN1
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	PLPPR4 (phospholipid phosphatase related 4)	protein interactions	9890	13	1	19454	50	ZNRF3
3.291e-02	-3.41	JAM2 (junctional adhesion molecule 2)	protein interactions	58494	13	1	19454	50	PARD3
3.291e-02	-3.41	NPR2 (natriuretic peptide receptor 2)	protein interactions	4882	13	1	19454	50	CAMK2G
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.309e-02	-3.41	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	3	18204	49	CDH20,SPARCL1,PCDH9
3.310e-02	-3.41	bladder	COSMIC cancer mutations	bladder	14112	46	16828	49	GPM6A,RFX4,PARD3B,ABLIM1,PCDH9,BMPR1B,PTGDS,SLC1A2,SLC1A3,ZBTB20,NFIA,CTNND2,FBXL7,PARD3,MSI2,RYR3,NPAS3,GLIS3,PITPNC1,FGFR3,LSAMP,TRPS1,RANBP3L,CAMK2G,ATP1A2,TNIK,HIF3A,SOX5,GPC5,ATP13A4,CDH20,PREX2,SFXN5,ZNRF3,MACF1,SPARCL1,MAML2,SLC4A4,NRXN1,PTPRZ1,RORA,NTM,AHCYL2,PAMR1,DTNA,ITPR2
3.310e-02	-3.41	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	46	16828	49	CAMK2G,ATP1A2,TRPS1,RANBP3L,GLIS3,PITPNC1,LSAMP,FGFR3,NPAS3,MSI2,RYR3,ZBTB20,CTNND2,NFIA,FBXL7,PARD3,PCDH9,SLC1A2,BMPR1B,PTGDS,SLC1A3,GPM6A,PARD3B,RFX4,ABLIM1,DTNA,ITPR2,NRXN1,SLC4A4,RORA,AHCYL2,NTM,PTPRZ1,PAMR1,MAML2,SFXN5,ZNRF3,MACF1,SPARCL1,PREX2,SOX5,HIF3A,ATP13A4,GPC5,CDH20,TNIK
3.321e-02	-3.40	MH1	pfam domains	PF03165	12	1	17795	50	NFIA
3.363e-02	-3.39	CEP170P1 (centrosomal protein 170 pseudogene 1)	protein interactions	645455	112	2	19454	50	MACF1,TRPS1
3.387e-02	-3.39	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	49	ATP1A2,NTM,MACF1,SLC4A4,PARD3B,NPAS3,ZBTB20,TRPS1
3.388e-02	-3.38	regulation of developmental process	biological process	GO:0050793	2540	12	18204	49	FGFR3,MACF1,NRXN1,TNIK,CST3,RORA,PARD3,PTPRZ1,SOX5,RANBP3L,TRPS1,BMPR1B
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.395e-02	-3.38	monoatomic cation:bicarbonate symporter activity	molecular function	GO:0140410	13	1	18094	48	SLC4A4
3.396e-02	-3.38	regulation of nervous system development	biological process	GO:0051960	456	4	18204	49	PTPRZ1,PARD3,NRXN1,MACF1
3.418e-02	-3.38	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	7	19454	50	PITPNC1,MACF1,CAMK2G,ABLIM1,NHSL1,PARD3B,PARD3
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	ZNRF3,DTNA
3.439e-02	-3.37	regulation of canonical Wnt signaling pathway	biological process	GO:0060828	265	3	18204	49	GPC5,CTNND2,ZNRF3
3.440e-02	-3.37	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	FGFR3
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	PREX2
3.444e-02	-3.37	postsynaptic specialization assembly	biological process	GO:0098698	13	1	18204	49	NRXN1
3.444e-02	-3.37	T-helper 17 cell differentiation	biological process	GO:0072539	13	1	18204	49	RORA
3.444e-02	-3.37	prepulse inhibition	biological process	GO:0060134	13	1	18204	49	CTNNA2
3.444e-02	-3.37	glial cell fate commitment	biological process	GO:0021781	13	1	18204	49	NFIA
3.444e-02	-3.37	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	49	ATP1A2
3.444e-02	-3.37	cerebellar Purkinje cell differentiation	biological process	GO:0021702	13	1	18204	49	RORA
3.444e-02	-3.37	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	49	ATP1A2
3.456e-02	-3.37	animal organ development	biological process	GO:0048513	2846	13	18204	49	GPM6A,NFIA,ABLIM1,CTNNA2,ATP1A2,SOX5,RFX4,FGFR3,RORA,PCDH9,SLC1A2,RANBP3L,BMPR1B
3.464e-02	-3.36	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	4	ATP1A2
3.464e-02	-3.36	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	4	ATP1A2
3.466e-02	-3.36	synaptic signaling	biological process	GO:0099536	459	4	18204	49	SLC1A3,NRXN1,SLC1A2,DTNA
3.481e-02	-3.36	postsynapse organization	biological process	GO:0099173	109	2	18204	49	NRXN1,CTNND2
3.484e-02	-3.36	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	28	FGFR3
3.484e-02	-3.36	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	28	ITPR2
3.484e-02	-3.36	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	1	10285	28	MAML2
3.484e-02	-3.36	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	28	FGFR3
3.484e-02	-3.36	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	1	10285	28	MAML2
3.484e-02	-3.36	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	28	FGFR3
3.487e-02	-3.36	RNA polymerase II cis-regulatory region sequence-specific DNA binding	molecular function	GO:0000978	1180	7	18094	48	HIF3A,SOX5,RFX4,GLIS3,ZBTB20,NFIA,RORA
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	CDH20,PCDH9
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	RYR3,ITPR2
3.527e-02	-3.34	ACTB (actin beta)	protein interactions	60	958	6	19454	50	NHSL1,SFXN5,ABLIM1,MACF1,DTNA,AHCYL2
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	CTNND2,PARD3
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	NFIA,TRPS1
3.537e-02	-3.34	protein localization to membrane	biological process	GO:0072657	462	4	18204	49	PARD3,TNIK,NRXN1,MACF1
3.538e-02	-3.34	phosphatase activity	molecular function	GO:0016791	272	3	18094	48	PTPRZ1,CAMK2G,ATP1A2
3.538e-02	-3.34	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	48	ZBTB20,TRPS1,GLIS3
3.540e-02	-3.34	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	50	FGFR3
3.540e-02	-3.34	CTSO (cathepsin O)	protein interactions	1519	14	1	19454	50	CST3
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	ZNRF3
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	TPSAB1 (tryptase alpha/beta 1)	protein interactions	7177	14	1	19454	50	CAMK2G
3.540e-02	-3.34	VSX2 (visual system homeobox 2)	protein interactions	338917	14	1	19454	50	AHCYL2
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	1	19454	50	CAMK2G
3.540e-02	-3.34	SYT5 (synaptotagmin 5)	protein interactions	6861	14	1	19454	50	NRXN1
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.553e-02	-3.34	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	48	16828	49	MAML2,PAMR1,PTPRZ1,AHCYL2,NTM,RORA,SLC4A4,NRXN1,ITPR2,DTNA,TNIK,CDH20,GPC5,ATP13A4,SOX5,HIF3A,PREX2,SPARCL1,MACF1,SFXN5,ZNRF3,NHSL1,NPAS3,FGFR3,LSAMP,PITPNC1,GLIS3,NKAIN3,RANBP3L,TRPS1,ATP1A2,CAMK2G,ABLIM1,PARD3B,RFX4,GPM6A,SLC1A3,PTGDS,BMPR1B,SLC1A2,PCDH9,PARD3,FBXL7,NFIA,CTNND2,ZBTB20,RYR3,MSI2
3.556e-02	-3.34	FOLN	smart domains	SM00274	9	1	9717	39	SPARCL1
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.579e-02	-3.33	HCO3TRNSPORT	prints domains	PR01231	10	1	5227	19	SLC4A4
3.586e-02	-3.33	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	2	19454	50	MACF1,SPARCL1
3.590e-02	-3.33	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	44	CTNNA2
3.590e-02	-3.33	-	gene3d domains	3.10.450.50	12	1	14470	44	CAMK2G
3.592e-02	-3.33	PRKACA (protein kinase cAMP-activated catalytic subunit alpha)	protein interactions	5566	486	4	19454	50	ITPR2,SLC4A4,PARD3,TNIK
3.593e-02	-3.33	regulation of cell projection organization	biological process	GO:0031344	683	5	18204	49	GPM6A,MACF1,CTNNA2,CAMK2G,TNIK
3.593e-02	-3.33	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	6	16828	49	PREX2,PAMR1,PCDH9,HIF3A,GLIS3,NFIA
3.612e-02	-3.32	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	49	FGFR3,TNIK,BMPR1B,CAMK2G
3.612e-02	-3.32	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	49	BMPR1B,CAMK2G,FGFR3,TNIK
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	TRPS1,NFIA
3.642e-02	-3.31	SYT6 (synaptotagmin 6)	protein interactions	148281	117	2	19454	50	AHCYL2,NRXN1
3.646e-02	-3.31	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	5	16828	49	NFIA,CAMK2G,PREX2,PTPRZ1,NTM
3.647e-02	-3.31	Dppa3 (developmental pluripotency-associated 3)	protein interactions	73708	284	3	19454	50	CAMK2G,MSI2,ATP1A2
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.678e-02	-3.30	bHLH_dom	interpro domains	IPR011598	112	2	18521	50	HIF3A,NPAS3
3.678e-02	-3.30	HLH_DNA-bd_sf	interpro domains	IPR036638	112	2	18521	50	HIF3A,NPAS3
3.699e-02	-3.30	PLCD3 (phospholipase C delta 3)	protein interactions	113026	118	2	19454	50	AHCYL2,TNIK
3.704e-02	-3.30	cellular response to ethanol	biological process	GO:0071361	14	1	18204	49	ITPR2
3.704e-02	-3.30	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	49	ATP1A2
3.704e-02	-3.30	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	49	ATP1A2
3.704e-02	-3.30	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	49	RYR3
3.704e-02	-3.30	regulation of skeletal muscle adaptation	biological process	GO:0014733	14	1	18204	49	CAMK2G
3.704e-02	-3.30	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	49	SLC1A2
3.715e-02	-3.29	Neurexin-like	interpro domains	IPR003585	14	1	18521	50	NRXN1
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.721e-02	-3.29	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	49	FGFR3
3.721e-02	-3.29	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	49	FGFR3
3.721e-02	-3.29	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	49	FGFR3
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	PREX2
3.745e-02	-3.28	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	3	19454	50	DTNA,PARD3B,PARD3
3.747e-02	-3.28	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	28	ABLIM1
3.749e-02	-3.28	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	4	ATP1A2
3.750e-02	-3.28	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	2	16828	49	PARD3,GPC5
3.764e-02	-3.28	Ion_trans	pfam domains	PF00520	109	2	17795	50	RYR3,ITPR2
3.774e-02	-3.28	gliogenesis	biological process	GO:0042063	275	3	18204	49	PTPRZ1,PARD3,NFIA
3.777e-02	-3.28	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	49	PTGDS,RORA
3.779e-02	-3.28	NEDD4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	4734	494	4	19454	50	MAML2,FGFR3,TNIK,GLIS3
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	50	FGFR3
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	PCDH9,CDH20
3.808e-02	-3.27	telencephalon development	biological process	GO:0021537	276	3	18204	49	RFX4,SLC1A2,ATP1A2
3.808e-02	-3.27	learning or memory	biological process	GO:0007611	276	3	18204	49	PTPRZ1,ATP1A2,NRXN1
3.814e-02	-3.27	cis-regulatory region sequence-specific DNA binding	molecular function	GO:0000987	1203	7	18094	48	SOX5,RFX4,HIF3A,ZBTB20,NFIA,RORA,GLIS3
3.814e-02	-3.27	HOXB9 (homeobox B9)	protein interactions	3219	120	2	19454	50	AHCYL2,NFIA
3.835e-02	-3.26	Cholinergic synapse	KEGG pathways	hsa04725	112	2	7161	20	CAMK2G,ITPR2
3.851e-02	-3.26	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	4	16828	49	TNIK,FGFR3,CAMK2G,BMPR1B
3.864e-02	-3.25	GATA	pfam domains	PF00320	14	1	17795	50	TRPS1
3.881e-02	-3.25	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	49	PARD3B,HIF3A
3.894e-02	-3.25	localization	biological process	GO:0051179	4474	18	18204	49	RANBP3L,RYR3,SLC1A2,PTGDS,MACF1,ITPR2,SLC4A4,ATP1A2,PITPNC1,PARD3B,NRXN1,SLC1A3,ATP13A4,GPM6A,TNIK,CAMK2G,SFXN5,PARD3
3.902e-02	-3.24	LIPOCALIN	prosite domains	PS00213	11	1	12186	44	PTGDS
3.902e-02	-3.24	RANBD1	prosite domains	PS50196	11	1	12186	44	RANBP3L
3.902e-02	-3.24	GATA_ZN_FINGER_2	prosite domains	PS50114	11	1	12186	44	TRPS1
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.914e-02	-3.24	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	49	PTPRZ1,ATP13A4,SLC4A4
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	PCDH9,CDH20
3.930e-02	-3.24	SLMAP (sarcolemma associated protein)	protein interactions	7871	122	2	19454	50	CAMK2G,TNIK
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	DTNA,NHSL1
3.943e-02	-3.23	human chr13q31.3	chromosome location	human chr13q31.3	21	1	26134	50	GPC5
3.954e-02	-3.23	Cadherin	pfam domains	PF00028	112	2	17795	50	CDH20,PCDH9
3.964e-02	-3.23	system process	biological process	GO:0003008	2015	10	18204	49	SLC1A3,NRXN1,PTPRZ1,ABLIM1,SLC4A4,CTNNA2,SLC1A2,RYR3,DTNA,ATP1A2
3.964e-02	-3.23	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	49	ATP1A2
3.964e-02	-3.23	regulation of circadian sleep/wake cycle, sleep	biological process	GO:0045187	15	1	18204	49	PTGDS
3.964e-02	-3.23	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	49	ATP1A2
3.964e-02	-3.23	neuroblast division	biological process	GO:0055057	15	1	18204	49	SOX5
3.964e-02	-3.23	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	49	MACF1
3.964e-02	-3.23	cerebellar Purkinje cell layer formation	biological process	GO:0021694	15	1	18204	49	RORA
3.964e-02	-3.23	sarcoplasmic reticulum calcium ion transport	biological process	GO:0070296	15	1	18204	49	RYR3
3.964e-02	-3.23	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	49	FGFR3
3.964e-02	-3.23	response to caffeine	biological process	GO:0031000	15	1	18204	49	RYR3
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	SLC1A2
3.964e-02	-3.23	exit from mitosis	biological process	GO:0010458	15	1	18204	49	NFIA
3.964e-02	-3.23	synapse maturation	biological process	GO:0060074	15	1	18204	49	NFIA
3.967e-02	-3.23	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	49	RANBP3L,TRPS1,NKAIN3,CAMK2G,ATP1A2,NPAS3,GLIS3,LSAMP,FGFR3,PITPNC1,NFIA,CTNND2,ZBTB20,PARD3,FBXL7,RYR3,PARD3B,RFX4,GPM6A,ABLIM1,BMPR1B,SLC1A2,PCDH9,SLC1A3,DTNA,ITPR2,MAML2,SLC4A4,NRXN1,PAMR1,PTPRZ1,NTM,RORA,AHCYL2,PREX2,SFXN5,ZNRF3,NHSL1,SPARCL1,MACF1,TNIK,GPC5,ATP13A4,HIF3A,SOX5,CDH20
3.970e-02	-3.23	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	5	16828	49	FGFR3,PREX2,ABLIM1,TNIK,MACF1
3.975e-02	-3.23	NTF2-like_dom_sf	interpro domains	IPR032710	15	1	18521	50	CAMK2G
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	Znf_GATA	interpro domains	IPR000679	15	1	18521	50	TRPS1
3.977e-02	-3.22	KCNE3 (potassium voltage-gated channel subfamily E regulatory subunit 3)	protein interactions	10008	294	3	19454	50	PCDH9,ZNRF3,TNIK
3.980e-02	-3.22	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha	Pathway Interaction DB	hif1apathway	15	1	2226	6	HIF3A
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	NFIA,TRPS1
3.997e-02	-3.22	MFAP5-mediated ovarian cancer cell motility and invasiveness	WikiPathways	WP3301	12	1	5310	18	RYR3
3.997e-02	-3.22	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	18	BMPR1B
4.002e-02	-3.22	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	49	FGFR3
4.002e-02	-3.22	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	49	FGFR3
4.002e-02	-3.22	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	49	FGFR3
4.002e-02	-3.22	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	49	FGFR3
4.002e-02	-3.22	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	49	FGFR3
4.009e-02	-3.22	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	REACTOME pathways	R-HSA-2162123	15	1	10285	28	PTGDS
4.020e-02	-3.21	synapse assembly	biological process	GO:0007416	118	2	18204	49	NRXN1,GPM6A
4.023e-02	-3.21	Prot_kinase_dom	interpro domains	IPR000719	480	4	18521	50	CAMK2G,BMPR1B,FGFR3,TNIK
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.028e-02	-3.21	phospholipid binding	molecular function	GO:0005543	489	4	18094	48	PARD3,PARD3B,ITPR2,PITPNC1
4.035e-02	-3.21	CAMK1G (calcium/calmodulin dependent protein kinase IG)	protein interactions	57172	16	1	19454	50	CAMK2G
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA2
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	MACF1
4.035e-02	-3.21	FZD4 (frizzled class receptor 4)	protein interactions	8322	16	1	19454	50	ZNRF3
4.035e-02	-3.21	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	50	FGFR3
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.035e-02	-3.21	DUS1L (dihydrouridine synthase 1 like)	protein interactions	64118	16	1	19454	50	CAMK2G
4.035e-02	-3.21	SYTL2 (synaptotagmin like 2)	protein interactions	54843	16	1	19454	50	NRXN1
4.035e-02	-3.21	SYT9 (synaptotagmin 9)	protein interactions	143425	16	1	19454	50	NRXN1
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	50	FGFR3
4.035e-02	-3.21	SAPCD1 (suppressor APC domain containing 1)	protein interactions	401251	16	1	19454	50	CTNNA2
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	SYT4 (synaptotagmin 4)	protein interactions	6860	16	1	19454	50	NRXN1
4.053e-02	-3.21	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	7	16828	49	CTNND2,PREX2,ATP13A4,SLC4A4,FGFR3,NTM,MACF1
4.065e-02	-3.20	membrane protein complex	cellular component	GO:0098796	1261	7	19108	49	ATP1A2,RYR3,SLC1A2,SLC1A3,BMPR1B,CTNNA2,CDH20
4.079e-02	-3.20	SP7 (Sp7 transcription factor)	protein interactions	121340	297	3	19454	50	TRPS1,NFIA,SOX5
4.117e-02	-3.19	secondary active transmembrane transporter activity	molecular function	GO:0015291	289	3	18094	48	SLC4A4,SLC1A3,SLC1A2
4.131e-02	-3.19	extremity	COSMIC cancer mutations	extremity	1876	10	16828	49	ATP13A4,RYR3,PCDH9,FGFR3,CDH20,PITPNC1,PTPRZ1,PARD3,PREX2,FBXL7
4.134e-02	-3.19	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	50	ATP1A2
4.134e-02	-3.19	CNH	pfam domains	PF00780	15	1	17795	50	TNIK
4.144e-02	-3.18	regulation of nervous system process	biological process	GO:0031644	120	2	18204	49	NRXN1,PARD3
4.148e-02	-3.18	bicellular tight junction	cellular component	GO:0005923	126	2	19108	49	PARD3,PARD3B
4.163e-02	-3.18	oxysterol binding	molecular function	GO:0008142	16	1	18094	48	RORA
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	PITPNC1,GPM6A
4.171e-02	-3.18	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	7	16828	49	CDH20,ATP13A4,SLC1A2,RYR3,GPC5,SOX5,PARD3
4.223e-02	-3.16	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	49	ATP1A2
4.223e-02	-3.16	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	49	ATP1A2
4.223e-02	-3.16	S-adenosylmethionine metabolic process	biological process	GO:0046500	16	1	18204	49	AHCYL2
4.223e-02	-3.16	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	49	SLC1A2
4.223e-02	-3.16	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	49	ATP1A2
4.223e-02	-3.16	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	49	SLC1A3
4.223e-02	-3.16	neuron cell-cell adhesion	biological process	GO:0007158	16	1	18204	49	NRXN1
4.223e-02	-3.16	regulation of Wnt signaling pathway, planar cell polarity pathway	biological process	GO:2000095	16	1	18204	49	ZNRF3
4.223e-02	-3.16	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	49	ATP1A2
4.223e-02	-3.16	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	3	16828	49	SOX5,RYR3,CDH20
4.225e-02	-3.16	EF_HAND_2	prosite domains	PS50222	215	3	12186	44	RYR3,SPARCL1,MACF1
4.226e-02	-3.16	PAX9 (paired box 9)	protein interactions	5083	127	2	19454	50	NFIA,TRPS1
4.250e-02	-3.16	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	49	RYR3,ATP13A4,PCDH9,ITPR2,ATP1A2,MACF1,PARD3B,CTNND2
4.274e-02	-3.15	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	7	16828	49	RYR3,CAMK2G,CTNND2,MAML2,FGFR3,RORA,TNIK
4.282e-02	-3.15	ureter	COSMIC cancer mutations	ureter	15	1	16828	49	FGFR3
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	Shcbp1 (Shc SH2-domain binding protein 1)	protein interactions	20419	17	1	19454	50	GPC5
4.282e-02	-3.15	FAM163B (family with sequence similarity 163 member B)	protein interactions	642968	17	1	19454	50	CAMK2G
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	KRTAP19-3 (keratin associated protein 19-3)	protein interactions	337970	17	1	19454	50	CAMK2G
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	NOTCH4 (notch receptor 4)	protein interactions	4855	17	1	19454	50	MAML2
4.286e-02	-3.15	TEAD2 (TEA domain transcription factor 2)	protein interactions	8463	128	2	19454	50	TRPS1,ZBTB20
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	SOX5,MACF1
4.286e-02	-3.15	SYT2 (synaptotagmin 2)	protein interactions	127833	128	2	19454	50	NRXN1,AHCYL2
4.286e-02	-3.15	MYB (MYB proto-oncogene, transcription factor)	protein interactions	4602	128	2	19454	50	NFIA,TRPS1
4.297e-02	-3.15	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	50	DTNA,PREX2,AHCYL2,SLC1A3,PARD3,MACF1
4.321e-02	-3.14	CARM1 (coactivator associated arginine methyltransferase 1)	protein interactions	10498	304	3	19454	50	DTNA,CAMK2G,RORA
4.323e-02	-3.14	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	18	RYR3
4.329e-02	-3.14	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	49	FGFR3,TNIK,CAMK2G,BMPR1B
4.330e-02	-3.14	RanBD	smart domains	SM00160	11	1	9717	39	RANBP3L
4.334e-02	-3.14	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	5	16828	49	CAMK2G,BMPR1B,TNIK,SPARCL1,FGFR3
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	ZBTB20,SOX5
4.347e-02	-3.14	Oocyte meiosis	KEGG pathways	hsa04114	120	2	7161	20	ITPR2,CAMK2G
4.347e-02	-3.14	Oocyte meiosis	KEGG pathways	ko04114	120	2	7161	20	ITPR2,CAMK2G
4.350e-02	-3.13	cellular response to growth factor stimulus	biological process	GO:0071363	494	4	18204	49	BMPR1B,NFIA,SOX5,FGFR3
4.388e-02	-3.13	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	49	TNIK,FGFR3,CAMK2G,BMPR1B
4.407e-02	-3.12	DVL1 (dishevelled segment polarity protein 1)	protein interactions	1855	130	2	19454	50	ZNRF3,PARD3
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.428e-02	-3.12	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	5	16828	49	FGFR3,SPARCL1,TNIK,BMPR1B,CAMK2G
4.449e-02	-3.11	tight junction	cellular component	GO:0070160	131	2	19108	49	PARD3B,PARD3
4.467e-02	-3.11	regulation of cellular process	biological process	GO:0050794	11468	37	18204	49	HIF3A,ITPR2,GPC5,PTGDS,SLC1A2,BMPR1B,NRXN1,SLC1A3,GPM6A,NFIA,GLIS3,SPARCL1,SOX5,CTNND2,DTNA,TRPS1,FGFR3,MACF1,NPAS3,RORA,SLC4A4,PTPRZ1,ZBTB20,ZNRF3,RANBP3L,RYR3,PREX2,TNIK,MAML2,CAMK2G,CTNNA2,CST3,PARD3,ATP1A2,PITPNC1,MSI2,RFX4
4.468e-02	-3.11	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	2	19454	50	NFIA,SOX5
4.468e-02	-3.11	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	2	19454	50	SOX5,NFIA
4.468e-02	-3.11	NCOA2 (nuclear receptor coactivator 2)	protein interactions	10499	131	2	19454	50	NFIA,RORA
4.477e-02	-3.11	Helix-loop-helix DNA-binding domain	gene3d domains	4.10.280.10	111	2	14470	44	NPAS3,HIF3A
4.481e-02	-3.11	cell population proliferation	biological process	GO:0008283	726	5	18204	49	FGFR3,SOX5,ZNRF3,RORA,NFIA
4.481e-02	-3.11	T-helper 17 type immune response	biological process	GO:0072538	17	1	18204	49	RORA
4.481e-02	-3.11	viral genome replication	biological process	GO:0019079	17	1	18204	49	NFIA
4.481e-02	-3.11	cGMP metabolic process	biological process	GO:0046068	17	1	18204	49	RORA
4.481e-02	-3.11	microvillus assembly	biological process	GO:0030033	17	1	18204	49	TNIK
4.481e-02	-3.11	cell migration in hindbrain	biological process	GO:0021535	17	1	18204	49	CTNNA2
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	SLC1A2
4.481e-02	-3.11	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	49	ATP1A2
4.481e-02	-3.11	cellular response to ATP	biological process	GO:0071318	17	1	18204	49	RYR3
4.481e-02	-3.11	ureter development	biological process	GO:0072189	17	1	18204	49	NFIA
4.481e-02	-3.11	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	49	ATP1A2
4.493e-02	-3.10	PAC	interpro domains	IPR001610	17	1	18521	50	HIF3A
4.493e-02	-3.10	Cystatin_dom	interpro domains	IPR000010	17	1	18521	50	CST3
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.507e-02	-3.10	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	49	16828	49	PTPRZ1,AHCYL2,RORA,NTM,PAMR1,SLC4A4,NRXN1,MAML2,ITPR2,DTNA,CDH20,SOX5,HIF3A,GPC5,ATP13A4,TNIK,CST3,MACF1,SPARCL1,ZNRF3,NHSL1,SFXN5,PREX2,PITPNC1,FGFR3,LSAMP,GLIS3,NPAS3,ATP1A2,CAMK2G,NKAIN3,TRPS1,RANBP3L,SLC1A3,PCDH9,PTGDS,BMPR1B,SLC1A2,ABLIM1,GPM6A,RFX4,PARD3B,MSI2,RYR3,FBXL7,PARD3,ZBTB20,NFIA,CTNND2
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	PTGFR (prostaglandin F receptor)	protein interactions	5737	18	1	19454	50	PTGDS
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.530e-02	-3.09	STRN (striatin)	protein interactions	6801	132	2	19454	50	TNIK,CAMK2G
4.531e-02	-3.09	positive regulation of nervous system development	biological process	GO:0051962	296	3	18204	49	PTPRZ1,NRXN1,MACF1
4.532e-02	-3.09	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	REACTOME pathways	R-HSA-2173791	17	1	10285	28	PARD3
4.532e-02	-3.09	Unblocking of NMDA receptor, glutamate binding and activation	REACTOME pathways	R-HSA-438066	17	1	10285	28	CAMK2G
4.532e-02	-3.09	CREB phosphorylation through the activation of CaMKII	REACTOME pathways	R-HSA-442729	17	1	10285	28	CAMK2G
4.532e-02	-3.09	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	28	ITPR2
4.557e-02	-3.09	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	7	16828	49	RORA,FGFR3,RYR3,CAMK2G,TNIK,MAML2,CTNND2
4.561e-02	-3.09	normal	COSMIC cancer mutations	normal	16	1	16828	49	FGFR3
4.561e-02	-3.09	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	49	FGFR3
4.561e-02	-3.09	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	49	FGFR3
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	FGFR3
4.565e-02	-3.09	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	49	BMPR1B,CAMK2G,FGFR3,TNIK
4.569e-02	-3.09	carboxylic acid transport	biological process	GO:0046942	297	3	18204	49	SFXN5,SLC1A3,SLC1A2
4.569e-02	-3.09	muscle system process	biological process	GO:0003012	297	3	18204	49	DTNA,ATP1A2,RYR3
4.578e-02	-3.08	Neural Crest Differentiation	WikiPathways	WP2064	102	2	5310	18	SOX5,FGFR3
4.590e-02	-3.08	cell-cell junction assembly	biological process	GO:0007043	127	2	18204	49	CDH20,PARD3
4.607e-02	-3.08	organic acid transport	biological process	GO:0015849	298	3	18204	49	SLC1A3,SLC1A2,SFXN5
4.615e-02	-3.08	cell cortex	cellular component	GO:0005938	313	3	19108	49	PARD3B,ITPR2,PARD3
4.636e-02	-3.07	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	4	12186	44	TNIK,BMPR1B,FGFR3,CAMK2G
4.652e-02	-3.07	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	49	ITPR2,RYR3,SLC1A2,SLC1A3
4.653e-02	-3.07	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	50	GPM6A,NTM
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.673e-02	-3.06	ZZ	pfam domains	PF00569	17	1	17795	50	DTNA
4.673e-02	-3.06	Carb_anhydrase	pfam domains	PF00194	17	1	17795	50	PTPRZ1
4.673e-02	-3.06	Cystatin	pfam domains	PF00031	17	1	17795	50	CST3
4.696e-02	-3.06	Cadherins	gene3d domains	2.60.40.60	114	2	14470	44	PCDH9,CDH20
4.714e-02	-3.05	DWA	smart domains	SM00523	12	1	9717	39	NFIA
4.714e-02	-3.05	ZnF_GATA	smart domains	SM00401	12	1	9717	39	TRPS1
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	NFIA,TRPS1
4.716e-02	-3.05	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	50	NFIA,SOX5
4.720e-02	-3.05	response to organophosphorus	biological process	GO:0046683	129	2	18204	49	ITPR2,RYR3
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	PARD3B,RFX4,GPM6A,ABLIM1,SLC1A2,BMPR1B,PTGDS,PCDH9,SLC1A3,CTNND2,NFIA,ZBTB20,PARD3,FBXL7,RYR3,MSI2,NPAS3,GLIS3,FGFR3,LSAMP,PITPNC1,RANBP3L,TRPS1,NKAIN3,CAMK2G,ATP1A2,CST3,TNIK,ATP13A4,GPC5,SOX5,HIF3A,CDH20,PREX2,ZNRF3,SFXN5,NHSL1,SPARCL1,MACF1,MAML2,NRXN1,SLC4A4,PAMR1,RORA,NTM,AHCYL2,PTPRZ1,DTNA,ITPR2
4.737e-02	-3.05	circulatory system process	biological process	GO:0003013	508	4	18204	49	SLC4A4,ATP1A2,SLC1A3,SLC1A2
4.738e-02	-3.05	positive regulation of myelination	biological process	GO:0031643	18	1	18204	49	PARD3
4.738e-02	-3.05	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	49	CTNND2
4.738e-02	-3.05	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	49	ATP1A2
4.738e-02	-3.05	receptor catabolic process	biological process	GO:0032801	18	1	18204	49	ZNRF3
4.738e-02	-3.05	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	49	RORA
4.738e-02	-3.05	regulation of extracellular matrix disassembly	biological process	GO:0010715	18	1	18204	49	CST3
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.764e-02	-3.04	astrocyte projection	cellular component	GO:0097449	19	1	19108	49	SLC1A2
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.768e-02	-3.04	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma	683	5	16828	49	ZBTB20,PARD3B,NRXN1,MACF1,PARD3
4.768e-02	-3.04	primary_central_nervous_system_lymphoma	COSMIC cancer mutations	primary_central_nervous_system_lymphoma	683	5	16828	49	PARD3B,NRXN1,ZBTB20,PARD3,MACF1
4.774e-02	-3.04	NLGN1 (neuroligin 1)	protein interactions	22871	19	1	19454	50	NRXN1
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	1	19454	50	CAMK2G
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	LTC4S (leukotriene C4 synthase)	protein interactions	4056	19	1	19454	50	CAMK2G
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	SYT7 (synaptotagmin 7)	protein interactions	9066	19	1	19454	50	NRXN1
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	Mtx1 (metaxin 1)	protein interactions	17827	19	1	19454	50	CAMK2G
4.785e-02	-3.04	anion binding	molecular function	GO:0043168	2412	11	18094	48	ATP13A4,ATP1A2,FGFR3,PITPNC1,ITPR2,PARD3,PTGDS,CAMK2G,TNIK,SLC1A3,BMPR1B
4.792e-02	-3.04	SHC-mediated cascade:FGFR3	REACTOME pathways	R-HSA-5654704	18	1	10285	28	FGFR3
4.792e-02	-3.04	PI-3K cascade:FGFR3	REACTOME pathways	R-HSA-5654710	18	1	10285	28	FGFR3
4.793e-02	-3.04	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	49	PREX2,ATP1A2,TNIK
4.839e-02	-3.03	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.839e-02	-3.03	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	49	FGFR3
4.839e-02	-3.03	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	49	FGFR3
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX5,NFIA
4.852e-02	-3.03	carboxylic acid transmembrane transport	biological process	GO:1905039	131	2	18204	49	SLC1A3,SLC1A2
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.879e-02	-3.02	transport	biological process	GO:0006810	3615	15	18204	49	PITPNC1,ATP1A2,SFXN5,CAMK2G,GPM6A,ATP13A4,SLC1A3,NRXN1,RYR3,SLC1A2,PTGDS,RANBP3L,SLC4A4,ITPR2,MACF1
4.893e-02	-3.02	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	37	16828	49	RYR3,SFXN5,NHSL1,MACF1,SPARCL1,ZBTB20,CTNND2,FBXL7,PREX2,PARD3,SOX5,PCDH9,SLC1A2,ATP13A4,GPC5,CDH20,SLC1A3,GPM6A,RFX4,ABLIM1,TNIK,DTNA,CAMK2G,ITPR2,ATP1A2,TRPS1,RANBP3L,NKAIN3,NRXN1,RORA,AHCYL2,PTPRZ1,PAMR1,LSAMP,FGFR3,NPAS3,MAML2
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.966e-02	-3.00	cell division	biological process	GO:0051301	516	4	18204	49	PARD3,FBXL7,PARD3B,SOX5
4.987e-02	-3.00	ligand-gated monoatomic cation channel activity	molecular function	GO:0099094	135	2	18094	48	ITPR2,RYR3
4.995e-02	-3.00	regulation of circadian sleep/wake cycle	biological process	GO:0042749	19	1	18204	49	PTGDS
4.995e-02	-3.00	excitatory synapse assembly	biological process	GO:1904861	19	1	18204	49	NRXN1
4.995e-02	-3.00	negative regulation of peptidyl-threonine phosphorylation	biological process	GO:0010801	19	1	18204	49	PARD3
4.995e-02	-3.00	response to potassium ion	biological process	GO:0035864	19	1	18204	49	ATP1A2
4.995e-02	-3.00	vocalization behavior	biological process	GO:0071625	19	1	18204	49	NRXN1
4.995e-02	-3.00	regulation of neurotransmitter uptake	biological process	GO:0051580	19	1	18204	49	ATP1A2
4.995e-02	-3.00	cerebellar Purkinje cell layer morphogenesis	biological process	GO:0021692	19	1	18204	49	RORA
4.995e-02	-3.00	microvillus organization	biological process	GO:0032528	19	1	18204	49	TNIK