Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
1.478e-10	-22.63	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	33	16828	48	LIFR,ADCY2,NEBL,DTNA,ATP1A2,SPARCL1,CDH20,LSAMP,QKI,FMN2,CSGALNACT1,PCDH9,HPSE2,PRKCA,SLC1A3,GPM6A,SOX5,MACF1,ITPR2,NKAIN3,ATP13A4,NRG3,AQP4,NTRK2,EFEMP1,PREX2,DPP10,CTNND2,TNIK,NFIB,FBXL7,FGFR3,SLC1A2
1.057e-09	-20.67	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	45	16828	48	PCDH9,BMPR1B,NPAS3,HPSE2,ABLIM1,DTNA,SPARCL1,ADCY2,LSAMP,MSI2,SFXN5,CTNND2,DPP10,NHSL1,SLC1A2,FGFR3,FBXL7,NKAIN3,ITPR2,GPM6A,ZBTB20,PREX2,EFEMP1,NFIA,CSGALNACT1,QKI,FMN2,PRKCA,SLC1A3,NEBL,NTM,LIFR,PON2,CDH20,TNIK,NFIB,PARD3B,PITPNC1,NRG3,ATP13A4,MACF1,SOX5,GLIS3,PTPRZ1,NTRK2
1.320e-09	-20.45	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	18	16828	48	NPAS3,BMPR1B,NFIA,TNIK,NFIB,HPSE2,FBXL7,FGFR3,PRKCA,SLC1A2,SOX5,NKAIN3,ADCY2,ATP1A2,NRG3,NTRK2,PREX2,LSAMP
1.320e-09	-20.45	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	18	16828	48	NRG3,ATP1A2,NKAIN3,SOX5,ADCY2,LSAMP,PREX2,NTRK2,NFIA,TNIK,BMPR1B,NPAS3,PRKCA,SLC1A2,NFIB,FGFR3,HPSE2,FBXL7
5.172e-09	-19.08	brainstem	COSMIC cancer mutations	brainstem	3102	27	16828	48	ADCY2,LIFR,LSAMP,CDH20,NPAS3,QKI,FMN2,PCDH9,HPSE2,SLC1A3,PRKCA,NKAIN3,ITPR2,GPM6A,SOX5,ATP13A4,NRG3,PREX2,PTPRZ1,ZBTB20,CTNND2,TNIK,SFXN5,FGFR3,FBXL7,NFIB,SLC1A2
5.391e-09	-19.04	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	29	16828	48	PCDH9,CSGALNACT1,FMN2,QKI,PRKCA,HPSE2,NEBL,ATP1A2,SPARCL1,ADCY2,LIFR,LSAMP,CDH20,TNIK,CTNND2,SLC1A2,NFIB,FGFR3,FBXL7,NRG3,ATP13A4,AQP4,ITPR2,MACF1,NKAIN3,GPM6A,SOX5,PREX2,EFEMP1
1.306e-08	-18.15	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	24	16828	48	SOX5,GPM6A,ITPR2,NKAIN3,NRG3,ATP13A4,ZBTB20,PTPRZ1,PREX2,CTNND2,SFXN5,TNIK,NFIB,FBXL7,LIFR,ADCY2,CDH20,LSAMP,FMN2,QKI,PCDH9,HPSE2,PRKCA,SLC1A3
1.470e-08	-18.04	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	22	16828	48	NPAS3,FMN2,CSGALNACT1,BMPR1B,CTNND2,PCDH9,FBXL7,HPSE2,NFIB,SLC1A2,SLC1A3,NHSL1,ADCY2,GPM6A,SOX5,NKAIN3,ITPR2,NRG3,ATP13A4,NTRK2,PREX2,LSAMP
1.470e-08	-18.04	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	22	16828	48	CSGALNACT1,BMPR1B,FMN2,NPAS3,PCDH9,HPSE2,SLC1A3,ADCY2,LSAMP,CTNND2,NFIB,FBXL7,NHSL1,SLC1A2,NKAIN3,ITPR2,SOX5,GPM6A,NRG3,ATP13A4,NTRK2,PREX2
2.230e-08	-17.62	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	48	NRG3,ATP13A4,SOX5,GPM6A,ITPR2,NKAIN3,ZBTB20,PTPRZ1,PREX2,GLIS3,NTRK2,TNIK,CTNND2,SLC1A2,NFIB,FBXL7,NEBL,LIFR,NTM,ADCY2,LSAMP,NFIA,PCDH9,FMN2,CSGALNACT1,BMPR1B,SLC1A3,MGAT4C,HPSE2
2.230e-08	-17.62	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	48	NTRK2,ZBTB20,GLIS3,PTPRZ1,PREX2,ITPR2,NKAIN3,SOX5,GPM6A,NRG3,ATP13A4,NFIB,FBXL7,SLC1A2,CTNND2,TNIK,LSAMP,NTM,ADCY2,LIFR,NEBL,HPSE2,MGAT4C,SLC1A3,CSGALNACT1,BMPR1B,FMN2,NFIA,PCDH9
5.405e-08	-16.73	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	39	16828	48	LIFR,ADCY2,NTM,NEBL,ABLIM1,PON2,LSAMP,FMN2,NPAS3,QKI,CSGALNACT1,PCDH9,NFIA,HPSE2,SLC1A3,PRKCA,GPM6A,SOX5,MACF1,ITPR2,NKAIN3,PITPNC1,ATP13A4,NRG3,NTRK2,PTPRZ1,PREX2,GLIS3,ZBTB20,DPP10,CTNND2,SFXN5,TNIK,FBXL7,FGFR3,NFIB,PARD3B,SLC1A2,NHSL1
7.346e-08	-16.43	lymph_node	COSMIC cancer mutations	lymph_node	1703	19	16828	48	LIFR,ITPR2,SOX5,GPM6A,ATP13A4,NRG3,NEBL,DTNA,NTRK2,LSAMP,CTNND2,DPP10,TNIK,PCDH9,SFXN5,FGFR3,PARD3B,SLC1A3,PRKCA
1.359e-07	-15.81	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	24	16828	48	FMN2,PCDH9,HPSE2,SLC1A3,PRKCA,ADCY2,LIFR,NEBL,LSAMP,CTNND2,SFXN5,FBXL7,PARD3B,NFIB,SLC1A2,NKAIN3,ITPR2,GPM6A,SOX5,NRG3,ATP13A4,NTRK2,EFEMP1,PREX2
1.389e-07	-15.79	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	13	16828	48	SLC1A2,HPSE2,FBXL7,NFIB,PCDH9,LSAMP,PREX2,NTRK2,NRG3,ATP1A2,ADCY2,NKAIN3,SOX5
1.498e-07	-15.71	cerebellum	COSMIC cancer mutations	cerebellum	769	13	16828	48	ITPR2,CTNND2,DPP10,QKI,NPAS3,NRG3,ABLIM1,NEBL,PCDH9,PARD3B,NTRK2,HPSE2,PTPRZ1
2.036e-07	-15.41	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	12	16828	48	ITPR2,NRG3,ABLIM1,NEBL,NTRK2,PTPRZ1,NPAS3,CTNND2,DPP10,PCDH9,HPSE2,PARD3B
2.070e-07	-15.39	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	12	16828	48	PTPRZ1,NTRK2,NRG3,ABLIM1,NEBL,ITPR2,HPSE2,PARD3B,PCDH9,NPAS3,CTNND2,DPP10
2.193e-07	-15.33	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	48	16828	48	SOX5,MACF1,AQP4,NRG3,PITPNC1,ATP13A4,NTRK2,PTPRZ1,GLIS3,TNIK,NFIB,PARD3B,LIFR,NTM,NEBL,ATP1A2,CDH20,PON2,FMN2,QKI,CSGALNACT1,NFIA,SLC1A3,PRKCA,GPM6A,ITPR2,NKAIN3,EFEMP1,PREX2,ZBTB20,DPP10,CTNND2,SFXN5,MSI2,FBXL7,FGFR3,SLC1A2,NHSL1,ADCY2,SPARCL1,DTNA,ABLIM1,LSAMP,NPAS3,BMPR1B,PCDH9,HPSE2,MGAT4C
2.374e-07	-15.25	pharynx	COSMIC cancer mutations	pharynx	2696	23	16828	48	ATP1A2,DTNA,QKI,NPAS3,FMN2,NFIA,PCDH9,PRKCA,MACF1,ATP13A4,NRG3,PITPNC1,NTRK2,PTPRZ1,EFEMP1,PREX2,CTNND2,DPP10,SFXN5,PARD3B,FGFR3,NHSL1,SLC1A2
3.141e-07	-14.97	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	23	16828	48	PREX2,EFEMP1,NTRK2,NRG3,SOX5,GPM6A,NKAIN3,ITPR2,SLC1A2,NFIB,PARD3B,FBXL7,SFXN5,CTNND2,LSAMP,NEBL,LIFR,ADCY2,PRKCA,SLC1A3,HPSE2,PCDH9,FMN2
4.196e-07	-14.68	anatomical structure morphogenesis	biological process	GO:0009653	2225	20	18204	49	NEBL,NRG3,SOX5,NFIB,CTNND2,FGFR3,PREX2,PTPRZ1,ABLIM1,EFEMP1,GPM6A,CDH20,QKI,SLC1A3,PRKCA,NTRK2,CSGALNACT1,NFIA,TNIK,BMPR1B
4.487e-07	-14.62	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	38	16828	48	HPSE2,PRKCA,MGAT4C,SLC1A3,CSGALNACT1,BMPR1B,FMN2,QKI,PCDH9,LSAMP,PON2,CDH20,ADCY2,LIFR,ABLIM1,NEBL,SPARCL1,PARD3B,NFIB,FBXL7,NHSL1,SLC1A2,CTNND2,DPP10,TNIK,SFXN5,NTRK2,GLIS3,PTPRZ1,PREX2,EFEMP1,NKAIN3,MACF1,ITPR2,SOX5,GPM6A,NRG3,ATP13A4
9.065e-07	-13.91	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	20	16828	48	GPM6A,SOX5,NKAIN3,ITPR2,ADCY2,NEBL,NRG3,NTRK2,CDH20,PREX2,PTPRZ1,LSAMP,CTNND2,FMN2,PCDH9,FBXL7,HPSE2,FGFR3,SLC1A3,SLC1A2
1.167e-06	-13.66	cell periphery	cellular component	GO:0071944	6020	32	19108	49	SPARCL1,AQP4,TNIK,PTPRZ1,PRKCA,NTM,CTNND2,PCDH9,EFEMP1,NKAIN3,BMPR1B,GPM6A,HPSE2,ATP1A2,FMN2,NRG3,FGFR3,DTNA,SLC1A3,LIFR,ATP13A4,PARD3B,SLC1A2,LSAMP,PREX2,NTRK2,ADCY2,MACF1,CDH20,DPP10,ITPR2,PON2
1.565e-06	-13.37	nervous system development	biological process	GO:0007399	2185	19	18204	49	SLC1A3,BMPR1B,TNIK,NFIA,LSAMP,NTRK2,PCDH9,PTPRZ1,CTNND2,PREX2,NFIB,NRG3,SOX5,QKI,GPM6A,SLC1A2,MSI2,NTM,ATP1A2
2.102e-06	-13.07	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	10	16828	48	LSAMP,NRG3,PCDH9,SFXN5,CTNND2,NKAIN3,SOX5,GPM6A,ADCY2,FMN2
2.568e-06	-12.87	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	16	16828	48	NEBL,NRG3,SOX5,NKAIN3,ITPR2,ADCY2,PREX2,LSAMP,NTRK2,PCDH9,CTNND2,QKI,FMN2,SLC1A3,HPSE2,FBXL7
2.568e-06	-12.87	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	16	16828	48	HPSE2,FBXL7,SLC1A3,CTNND2,QKI,FMN2,PCDH9,NTRK2,LSAMP,PREX2,NKAIN3,ITPR2,SOX5,ADCY2,NRG3,NEBL
2.650e-06	-12.84	plasma membrane	cellular component	GO:0005886	5538	30	19108	49	PCDH9,NKAIN3,AQP4,TNIK,PTPRZ1,PRKCA,NTM,CTNND2,FMN2,ATP1A2,NRG3,FGFR3,GPM6A,BMPR1B,HPSE2,LSAMP,PREX2,ADCY2,NTRK2,SLC1A3,DTNA,LIFR,PARD3B,SLC1A2,ATP13A4,DPP10,ITPR2,PON2,CDH20,MACF1
2.955e-06	-12.73	system development	biological process	GO:0048731	3533	24	18204	49	PRKCA,NTRK2,TNIK,NFIB,PREX2,FGFR3,CTNND2,NEBL,NRG3,SOX5,PTPRZ1,EFEMP1,SLC1A2,MSI2,SLC1A3,CSGALNACT1,LSAMP,NFIA,BMPR1B,PCDH9,NTM,ATP1A2,QKI,GPM6A
3.365e-06	-12.60	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	13	19454	50	ATP1A2,SPARCL1,NFIB,AQP4,ABLIM1,QKI,GPM6A,MACF1,NHSL1,SLC1A3,LSAMP,PTPRZ1,MSI2
3.733e-06	-12.50	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	19	16828	48	NTRK2,LSAMP,PTPRZ1,CDH20,PREX2,ITPR2,NKAIN3,SOX5,GPM6A,ADCY2,NRG3,NEBL,FBXL7,HPSE2,SLC1A3,SLC1A2,CTNND2,FMN2,PCDH9
3.733e-06	-12.50	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	19	16828	48	NEBL,NRG3,SOX5,GPM6A,ITPR2,NKAIN3,ADCY2,CDH20,PTPRZ1,PREX2,LSAMP,NTRK2,PCDH9,CTNND2,FMN2,SLC1A3,SLC1A2,FBXL7,HPSE2
4.305e-06	-12.36	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	14	16828	48	HPSE2,PRKCA,CTNND2,DPP10,TNIK,PCDH9,LSAMP,EFEMP1,ADCY2,ITPR2,NKAIN3,SOX5,AQP4,NRG3
5.736e-06	-12.07	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	15	16828	48	QKI,FMN2,CTNND2,DPP10,SFXN5,NFIA,FGFR3,SLC1A2,PRKCA,NHSL1,ATP13A4,PITPNC1,ATP1A2,NTRK2,PREX2
5.736e-06	-12.07	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	15	16828	48	QKI,FMN2,DPP10,CTNND2,SFXN5,NFIA,FGFR3,SLC1A2,NHSL1,PRKCA,ATP1A2,ATP13A4,PITPNC1,NTRK2,PREX2
6.102e-06	-12.01	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	7	16828	48	NFIB,HPSE2,NPAS3,ADCY2,NFIA,NRG3,PCDH9
6.102e-06	-12.01	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	7	16828	48	NRG3,NFIA,PCDH9,NFIB,ADCY2,NPAS3,HPSE2
6.125e-06	-12.00	multicellular organism development	biological process	GO:0007275	3957	25	18204	49	TNIK,PRKCA,NTRK2,PTPRZ1,NEBL,NRG3,SOX5,NFIB,FGFR3,CTNND2,PREX2,CDH20,MSI2,EFEMP1,SLC1A2,SLC1A3,BMPR1B,LSAMP,CSGALNACT1,NFIA,PCDH9,GPM6A,QKI,NTM,ATP1A2
6.731e-06	-11.91	cartilage development	biological process	GO:0051216	173	6	18204	49	SOX5,CSGALNACT1,NFIB,NFIA,FGFR3,BMPR1B
6.972e-06	-11.87	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	24	16828	48	FMN2,NPAS3,BMPR1B,PCDH9,HPSE2,PRKCA,SLC1A3,MGAT4C,LIFR,ADCY2,DTNA,LSAMP,CTNND2,MSI2,TNIK,PARD3B,FBXL7,MACF1,PITPNC1,NRG3,NTRK2,PTPRZ1,PREX2,EFEMP1
6.972e-06	-11.87	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	24	16828	48	LIFR,ADCY2,MACF1,DTNA,PITPNC1,NRG3,NTRK2,PTPRZ1,EFEMP1,PREX2,LSAMP,NPAS3,FMN2,BMPR1B,CTNND2,PCDH9,TNIK,MSI2,FBXL7,HPSE2,PARD3B,SLC1A3,MGAT4C,PRKCA
7.147e-06	-11.85	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma	1263	14	16828	48	HPSE2,FGFR3,NTRK2,TNIK,NEBL,NRG3,ABLIM1,ATP13A4,FMN2,NTM,ADCY2,GPM6A,MACF1,CTNND2
7.147e-06	-11.85	plasma_cell_myeloma	COSMIC cancer mutations	plasma_cell_myeloma	1263	14	16828	48	FGFR3,HPSE2,CTNND2,FMN2,TNIK,NTRK2,MACF1,GPM6A,NTM,ADCY2,ABLIM1,NRG3,ATP13A4,NEBL
1.140e-05	-11.38	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	37	16828	48	NFIB,FBXL7,FGFR3,NHSL1,SLC1A2,DPP10,CTNND2,SFXN5,TNIK,NTRK2,PREX2,PTPRZ1,EFEMP1,GLIS3,SOX5,GPM6A,NKAIN3,MACF1,ITPR2,NRG3,ATP13A4,HPSE2,PRKCA,SLC1A3,FMN2,QKI,CSGALNACT1,BMPR1B,PCDH9,CDH20,PON2,LSAMP,LIFR,ADCY2,ATP1A2,NEBL,ABLIM1
1.189e-05	-11.34	cell morphogenesis	biological process	GO:0000902	687	10	18204	49	NFIB,CTNND2,PREX2,SLC1A3,PTPRZ1,NFIA,CDH20,BMPR1B,TNIK,GPM6A
1.209e-05	-11.32	nodular	COSMIC cancer mutations	nodular	1515	15	16828	48	FGFR3,CTNND2,NPAS3,FMN2,GLIS3,PTPRZ1,PREX2,CDH20,NTRK2,ABLIM1,ATP13A4,NEBL,ATP1A2,SPARCL1,MACF1
1.555e-05	-11.07	Glutamatergic synapse	KEGG pathways	ko04724	114	5	7161	21	SLC1A3,ITPR2,PRKCA,ADCY2,SLC1A2
1.555e-05	-11.07	Glutamatergic synapse	KEGG pathways	hsa04724	114	5	7161	21	SLC1A2,ITPR2,SLC1A3,ADCY2,PRKCA
1.776e-05	-10.94	tibia	COSMIC cancer mutations	tibia	836	11	16828	48	ABLIM1,TNIK,GPM6A,NKAIN3,MACF1,CTNND2,QKI,PREX2,LSAMP,NFIB,FGFR3
1.892e-05	-10.88	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	26	16828	48	CDH20,LIFR,ADCY2,NTM,HPSE2,FMN2,CSGALNACT1,NFIA,PCDH9,NTRK2,ZBTB20,PTPRZ1,PREX2,GPM6A,SOX5,MACF1,ITPR2,NRG3,ATP13A4,PARD3B,FBXL7,FGFR3,NHSL1,DPP10,CTNND2,TNIK
2.057e-05	-10.79	cell junction	cellular component	GO:0030054	2224	17	19108	49	GPM6A,CDH20,NRG3,ATP1A2,FGFR3,NFIA,PTPRZ1,TNIK,SLC1A3,SPARCL1,DTNA,SLC1A2,CTNND2,PARD3B,PCDH9,QKI,NTRK2
2.126e-05	-10.76	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	33	16828	48	PCDH9,CSGALNACT1,BMPR1B,FMN2,NPAS3,PRKCA,MGAT4C,HPSE2,ABLIM1,NEBL,ATP1A2,SPARCL1,ADCY2,LIFR,TNIK,SFXN5,CTNND2,DPP10,PARD3B,FGFR3,FBXL7,ATP13A4,NRG3,PITPNC1,AQP4,MACF1,ITPR2,GPM6A,SOX5,ZBTB20,GLIS3,PREX2,PTPRZ1
2.256e-05	-10.70	MAPT (microtubule associated protein tau)	protein interactions	4137	948	11	19454	50	SLC1A2,TNIK,PRKCA,SLC1A3,NTM,ATP1A2,GPM6A,CTNND2,ABLIM1,NEBL,LSAMP
2.501e-05	-10.60	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	17	16828	48	PREX2,PTPRZ1,LSAMP,GPM6A,MACF1,ITPR2,AQP4,NEBL,NRG3,ABLIM1,FGFR3,NFIB,FMN2,CSGALNACT1,DPP10,PCDH9,MSI2
2.671e-05	-10.53	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	35	16828	48	LSAMP,PON2,CDH20,ADCY2,LIFR,ABLIM1,ATP1A2,NEBL,HPSE2,PRKCA,SLC1A3,BMPR1B,CSGALNACT1,QKI,FMN2,PCDH9,NTRK2,GLIS3,PREX2,EFEMP1,NKAIN3,MACF1,ITPR2,SOX5,GPM6A,NRG3,ATP13A4,NFIB,FGFR3,FBXL7,NHSL1,SLC1A2,CTNND2,DPP10,SFXN5
2.698e-05	-10.52	anatomical structure development	biological process	GO:0048856	5207	28	18204	49	SPARCL1,PCDH9,NTM,ATP1A2,QKI,GPM6A,SLC1A3,NFIA,CSGALNACT1,LSAMP,BMPR1B,FMN2,PREX2,FGFR3,CTNND2,NFIB,SOX5,NRG3,NEBL,PTPRZ1,EFEMP1,SLC1A2,MSI2,ABLIM1,CDH20,NTRK2,PRKCA,TNIK
3.219e-05	-10.34	trunk	COSMIC cancer mutations	trunk	3554	23	16828	48	ATP13A4,NRG3,ABLIM1,NEBL,ATP1A2,SPARCL1,MACF1,SOX5,LIFR,LSAMP,GLIS3,PREX2,PTPRZ1,CDH20,NTRK2,PCDH9,CTNND2,DPP10,NPAS3,MGAT4C,SLC1A3,FGFR3,HPSE2
3.484e-05	-10.26	OCLN (occludin)	protein interactions	100506658	495	8	19454	50	FMN2,ABLIM1,NTRK2,MACF1,PRKCA,TNIK,DTNA,EFEMP1
3.552e-05	-10.25	connective tissue development	biological process	GO:0061448	232	6	18204	49	NFIA,CSGALNACT1,BMPR1B,FGFR3,NFIB,SOX5
3.599e-05	-10.23	neurogenesis	biological process	GO:0022008	1334	13	18204	49	QKI,GPM6A,NTM,PTPRZ1,NFIB,PREX2,CTNND2,SOX5,BMPR1B,TNIK,NFIA,NTRK2,SLC1A3
4.245e-05	-10.07	generation of neurons	biological process	GO:0048699	1158	12	18204	49	NTM,GPM6A,SOX5,PREX2,CTNND2,NFIB,PTPRZ1,NTRK2,NFIA,TNIK,BMPR1B,SLC1A3
4.271e-05	-10.06	CTF/NFI_DNA-bd_CS	interpro domains	IPR019739	4	2	18521	50	NFIB,NFIA
4.271e-05	-10.06	CTF/NFI	interpro domains	IPR000647	4	2	18521	50	NFIA,NFIB
4.271e-05	-10.06	CTF/NFI_DNA-bd_N	interpro domains	IPR019548	4	2	18521	50	NFIB,NFIA
4.271e-05	-10.06	CTF/NFI_DNA-bd-dom	interpro domains	IPR020604	4	2	18521	50	NFIA,NFIB
4.274e-05	-10.06	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	28	SLC1A2,SLC1A3
4.274e-05	-10.06	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	28	SLC1A2,SLC1A3
4.441e-05	-10.02	NfI_DNAbd_pre-N	pfam domains	PF10524	4	2	17795	49	NFIA,NFIB
4.441e-05	-10.02	CTF_NFI	pfam domains	PF00859	4	2	17795	49	NFIB,NFIA
4.567e-05	-9.99	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	13	16828	48	SPARCL1,ABLIM1,ATP13A4,NEBL,ATP1A2,MACF1,GLIS3,CDH20,PREX2,PTPRZ1,NTRK2,NPAS3,CTNND2
4.755e-05	-9.95	face	COSMIC cancer mutations	face	2139	17	16828	48	NFIB,FGFR3,DPP10,FMN2,CSGALNACT1,MSI2,PCDH9,PTPRZ1,PREX2,LSAMP,GPM6A,MACF1,ITPR2,NEBL,NRG3,ABLIM1,AQP4
5.381e-05	-9.83	developmental process	biological process	GO:0032502	5716	29	18204	49	NTRK2,PRKCA,TNIK,SLC1A2,EFEMP1,ABLIM1,MSI2,CDH20,PREX2,CTNND2,FGFR3,NFIB,SOX5,NRG3,NEBL,NHSL1,PTPRZ1,NFIA,LSAMP,CSGALNACT1,BMPR1B,FMN2,SLC1A3,NTM,ATP1A2,QKI,GPM6A,SPARCL1,PCDH9
5.392e-05	-9.83	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	8	16828	48	LSAMP,PRKCA,CTNND2,GPM6A,SFXN5,PCDH9,NRG3,ATP13A4
5.505e-05	-9.81	Thyroid hormone synthesis	KEGG pathways	ko04918	74	4	7161	21	ATP1A2,ITPR2,PRKCA,ADCY2
5.505e-05	-9.81	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	4	7161	21	ITPR2,ATP1A2,PRKCA,ADCY2
5.769e-05	-9.76	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	16	16828	48	ZBTB20,NEBL,SOX5,GPM6A,MACF1,ITPR2,MGAT4C,PARD3B,HPSE2,FGFR3,PCDH9,TNIK,NPAS3,FMN2,BMPR1B,CSGALNACT1
5.804e-05	-9.75	Gastric acid secretion	KEGG pathways	ko04971	75	4	7161	21	PRKCA,ADCY2,ATP1A2,ITPR2
5.804e-05	-9.75	Gastric acid secretion	KEGG pathways	hsa04971	75	4	7161	21	ATP1A2,ITPR2,PRKCA,ADCY2
5.842e-05	-9.75	larynx	COSMIC cancer mutations	larynx	1948	16	16828	48	MACF1,ITPR2,SOX5,GPM6A,NEBL,ZBTB20,BMPR1B,CSGALNACT1,NPAS3,FMN2,TNIK,PCDH9,PARD3B,FGFR3,HPSE2,MGAT4C
6.097e-05	-9.71	retina development in camera-type eye	biological process	GO:0060041	156	5	18204	49	BMPR1B,GPM6A,NFIB,NFIA,NTRK2
6.242e-05	-9.68	transmembrane receptor protein kinase activity	molecular function	GO:0019199	81	4	18094	48	EFEMP1,NTRK2,FGFR3,BMPR1B
6.277e-05	-9.68	CTF_NFI_1	prosite domains	PS00349	4	2	12186	40	NFIA,NFIB
6.277e-05	-9.68	CTF_NFI_2	prosite domains	PS51080	4	2	12186	40	NFIA,NFIB
6.406e-05	-9.66	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	46	16828	48	PCDH9,NPAS3,BMPR1B,MGAT4C,HPSE2,ABLIM1,SPARCL1,ADCY2,LSAMP,SFXN5,DPP10,CTNND2,NHSL1,SLC1A2,FBXL7,FGFR3,GPM6A,ITPR2,NKAIN3,ZBTB20,PREX2,EFEMP1,NFIA,FMN2,QKI,CSGALNACT1,PRKCA,SLC1A3,NEBL,ATP1A2,LIFR,NTM,CDH20,PON2,TNIK,PARD3B,NFIB,NRG3,PITPNC1,ATP13A4,AQP4,SOX5,MACF1,PTPRZ1,GLIS3,NTRK2
6.856e-05	-9.59	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	48	SLC1A2,SLC1A3
6.856e-05	-9.59	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	48	SLC1A3,SLC1A2
7.061e-05	-9.56	D-aspartate import across plasma membrane	biological process	GO:0070779	5	2	18204	49	SLC1A3,SLC1A2
7.061e-05	-9.56	D-aspartate transmembrane transport	biological process	GO:0070777	5	2	18204	49	SLC1A2,SLC1A3
7.070e-05	-9.56	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	49	SLC1A3,ATP1A2,SLC1A2
7.360e-05	-9.52	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	48	FGFR3,FBXL7,PARD3B,NFIB,SLC1A2,CTNND2,TNIK,SFXN5,NTRK2,GLIS3,EFEMP1,PTPRZ1,PREX2,ZBTB20,ITPR2,NKAIN3,MACF1,SOX5,GPM6A,NRG3,ATP13A4,PITPNC1,HPSE2,MGAT4C,SLC1A3,PRKCA,CSGALNACT1,BMPR1B,NPAS3,FMN2,PCDH9,NFIA,LSAMP,PON2,CDH20,NTM,ADCY2,LIFR,ABLIM1,DTNA,ATP1A2,NEBL
7.360e-05	-9.52	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	48	CSGALNACT1,BMPR1B,FMN2,NPAS3,NFIA,PCDH9,HPSE2,PRKCA,MGAT4C,SLC1A3,ADCY2,NTM,LIFR,ABLIM1,NEBL,ATP1A2,DTNA,PON2,LSAMP,CDH20,CTNND2,TNIK,SFXN5,NFIB,PARD3B,FGFR3,FBXL7,SLC1A2,NKAIN3,MACF1,ITPR2,SOX5,GPM6A,PITPNC1,NRG3,ATP13A4,NTRK2,ZBTB20,GLIS3,PTPRZ1,EFEMP1,PREX2
7.382e-05	-9.51	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	30	16828	48	NHSL1,SLC1A2,PARD3B,FGFR3,FBXL7,CTNND2,DPP10,GLIS3,PTPRZ1,PREX2,NTRK2,NRG3,AQP4,ITPR2,MACF1,NKAIN3,SOX5,GPM6A,SLC1A3,HPSE2,NFIA,PCDH9,NPAS3,FMN2,LSAMP,PON2,CDH20,NEBL,SPARCL1,ADCY2
7.693e-05	-9.47	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	11	16828	48	HPSE2,EFEMP1,LSAMP,PRKCA,ADCY2,SOX5,CTNND2,ITPR2,NKAIN3,PCDH9,NRG3
7.981e-05	-9.44	neuron development	biological process	GO:0048666	859	10	18204	49	PTPRZ1,SLC1A3,CTNND2,PREX2,NFIB,GPM6A,TNIK,BMPR1B,NTRK2,NTM
7.991e-05	-9.43	chondrocyte differentiation	biological process	GO:0002062	85	4	18204	49	NFIB,FGFR3,SOX5,BMPR1B
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	NTM,GPM6A,LSAMP
8.457e-05	-9.38	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	34	16828	48	DPP10,CTNND2,SFXN5,FBXL7,FGFR3,PARD3B,SLC1A2,NHSL1,SOX5,ITPR2,MACF1,AQP4,ATP13A4,PITPNC1,NRG3,NTRK2,PREX2,PTPRZ1,ZBTB20,FMN2,NPAS3,QKI,CSGALNACT1,PCDH9,NFIA,HPSE2,PRKCA,LIFR,NTM,ADCY2,NEBL,ATP1A2,CDH20,LSAMP
8.457e-05	-9.38	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	34	16828	48	NHSL1,SLC1A2,PARD3B,FBXL7,FGFR3,SFXN5,DPP10,CTNND2,ZBTB20,PREX2,PTPRZ1,NTRK2,ATP13A4,NRG3,PITPNC1,AQP4,SOX5,MACF1,ITPR2,PRKCA,HPSE2,NFIA,PCDH9,QKI,NPAS3,FMN2,CSGALNACT1,CDH20,LSAMP,ATP1A2,NEBL,LIFR,ADCY2,NTM
9.626e-05	-9.25	prostate	COSMIC cancer mutations	prostate	13883	48	16828	48	LSAMP,SPARCL1,ABLIM1,DTNA,ADCY2,MGAT4C,HPSE2,PCDH9,BMPR1B,NPAS3,EFEMP1,PREX2,ZBTB20,NKAIN3,ITPR2,GPM6A,SLC1A2,NHSL1,FGFR3,FBXL7,SFXN5,MSI2,CTNND2,DPP10,PON2,CDH20,NEBL,ATP1A2,NTM,LIFR,SLC1A3,PRKCA,NFIA,CSGALNACT1,FMN2,QKI,GLIS3,PTPRZ1,NTRK2,AQP4,PITPNC1,NRG3,ATP13A4,MACF1,SOX5,PARD3B,NFIB,TNIK
1.022e-04	-9.19	DAG and IP3 signaling	REACTOME pathways	R-HSA-1489509	34	3	10285	28	ADCY2,ITPR2,PRKCA
1.057e-04	-9.15	D-amino acid transport	biological process	GO:0042940	6	2	18204	49	SLC1A2,SLC1A3
1.057e-04	-9.15	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	49	SLC1A2,SLC1A3
1.112e-04	-9.10	neuron differentiation	biological process	GO:0030182	1081	11	18204	49	NFIB,PREX2,CTNND2,SLC1A3,PTPRZ1,NFIA,NTM,NTRK2,BMPR1B,TNIK,GPM6A
1.149e-04	-9.07	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	16	19108	49	SLC1A3,AQP4,DTNA,ABLIM1,PRKCA,SLC1A2,CTNND2,PCDH9,ADCY2,NFIB,NTRK2,GPM6A,BMPR1B,MACF1,FMN2,ATP1A2
1.186e-04	-9.04	Salivary secretion	KEGG pathways	ko04970	90	4	7161	21	ATP1A2,ITPR2,PRKCA,ADCY2
1.186e-04	-9.04	Salivary secretion	KEGG pathways	hsa04970	90	4	7161	21	ADCY2,PRKCA,ITPR2,ATP1A2
1.215e-04	-9.02	PLC-gamma1 signalling	REACTOME pathways	R-HSA-167021	36	3	10285	28	ITPR2,ADCY2,PRKCA
1.215e-04	-9.02	EGFR interacts with phospholipase C-gamma	REACTOME pathways	R-HSA-212718	36	3	10285	28	PRKCA,ITPR2,ADCY2
1.402e-04	-8.87	humerus	COSMIC cancer mutations	humerus	546	8	16828	48	NEBL,SFXN5,GPM6A,SOX5,NKAIN3,FMN2,ADCY2,PARD3B
1.463e-04	-8.83	Pancreatic secretion	KEGG pathways	ko04972	95	4	7161	21	ADCY2,PRKCA,ITPR2,ATP1A2
1.463e-04	-8.83	Pancreatic secretion	KEGG pathways	hsa04972	95	4	7161	21	ATP1A2,ITPR2,ADCY2,PRKCA
1.478e-04	-8.82	glial cell fate specification	biological process	GO:0021780	7	2	18204	49	NFIB,NFIA
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A3,SLC1A2
1.546e-04	-8.77	SDF	pfam domains	PF00375	7	2	17795	49	SLC1A2,SLC1A3
1.560e-04	-8.77	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	43	16828	48	ADCY2,DTNA,ABLIM1,SPARCL1,LSAMP,NPAS3,BMPR1B,PCDH9,HPSE2,NKAIN3,ITPR2,PREX2,EFEMP1,DPP10,CTNND2,MSI2,SFXN5,FBXL7,FGFR3,NHSL1,SLC1A2,LIFR,NTM,NEBL,ATP1A2,CDH20,PON2,QKI,FMN2,CSGALNACT1,NFIA,PRKCA,SLC1A3,SOX5,MACF1,ATP13A4,NRG3,NTRK2,PTPRZ1,GLIS3,TNIK,PARD3B,NFIB
1.711e-04	-8.67	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	42	SLC1A3,SLC1A2
1.729e-04	-8.66	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	48	CTNND2,NKAIN3,GPM6A,LSAMP
1.776e-04	-8.64	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	6	19454	50	NEBL,NHSL1,MACF1,DTNA,TNIK,ABLIM1
2.018e-04	-8.51	mouth	COSMIC cancer mutations	mouth	9004	38	16828	48	SFXN5,TNIK,CTNND2,SLC1A2,NHSL1,FBXL7,FGFR3,PARD3B,NRG3,ATP13A4,PITPNC1,GPM6A,SOX5,ITPR2,MACF1,PREX2,EFEMP1,PTPRZ1,ZBTB20,NTRK2,PCDH9,QKI,NPAS3,FMN2,CSGALNACT1,SLC1A3,MGAT4C,PRKCA,HPSE2,NEBL,DTNA,ATP1A2,ABLIM1,LIFR,ADCY2,NTM,CDH20,LSAMP
2.033e-04	-8.50	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	6	16828	48	SOX5,GPM6A,NKAIN3,FMN2,ADCY2,SFXN5
2.035e-04	-8.50	cell projection	cellular component	GO:0042995	2398	16	19108	49	ATP1A2,FMN2,BMPR1B,GPM6A,MACF1,PCDH9,NTRK2,NFIB,ADCY2,DTNA,AQP4,SLC1A3,PRKCA,ABLIM1,CTNND2,SLC1A2
2.183e-04	-8.43	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	40	SLC1A3,SLC1A2
2.183e-04	-8.43	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	40	SLC1A3,SLC1A2
2.267e-04	-8.39	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	23	16828	48	GPM6A,MACF1,PITPNC1,AQP4,NTRK2,PREX2,PTPRZ1,GLIS3,DPP10,CTNND2,TNIK,PARD3B,FBXL7,FGFR3,NHSL1,SLC1A2,ADCY2,NEBL,ATP1A2,NPAS3,FMN2,NFIA,PCDH9
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	LSAMP,NTM
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.329e-04	-8.37	EDTRNSPORT	prints domains	PR00173	7	2	5227	18	SLC1A2,SLC1A3
2.402e-04	-8.33	acidic amino acid transport	biological process	GO:0015800	45	3	18204	49	SLC1A2,SLC1A3,NTRK2
2.655e-04	-8.23	synapse	cellular component	GO:0045202	1473	12	19108	49	QKI,NTRK2,SLC1A2,CTNND2,PTPRZ1,TNIK,SLC1A3,SPARCL1,DTNA,NRG3,ATP1A2,GPM6A
2.660e-04	-8.23	central nervous system development	biological process	GO:0007417	995	10	18204	49	SLC1A2,ATP1A2,MSI2,NTRK2,QKI,BMPR1B,NFIB,NRG3,PCDH9,PTPRZ1
2.666e-04	-8.23	camera-type eye development	biological process	GO:0043010	335	6	18204	49	NTRK2,NFIA,EFEMP1,NFIB,GPM6A,BMPR1B
2.704e-04	-8.22	PLC beta mediated events	REACTOME pathways	R-HSA-112043	47	3	10285	28	PRKCA,ADCY2,ITPR2
2.864e-04	-8.16	SFN (stratifin)	protein interactions	2810	671	8	19454	50	PARD3B,TNIK,NFIB,NFIA,MAST4,MACF1,ABLIM1,FMN2
2.880e-04	-8.15	G-protein mediated events	REACTOME pathways	R-HSA-112040	48	3	10285	28	ADCY2,ITPR2,PRKCA
2.984e-04	-8.12	glial cell differentiation	biological process	GO:0010001	219	5	18204	49	PTPRZ1,QKI,NTRK2,NFIA,NFIB
3.013e-04	-8.11	neuron projection morphogenesis	biological process	GO:0048812	486	7	18204	49	TNIK,GPM6A,PTPRZ1,BMPR1B,NFIB,PREX2,CTNND2
3.150e-04	-8.06	mucosal	COSMIC cancer mutations	mucosal	2009	15	16828	48	EFEMP1,PREX2,NRG3,ATP13A4,ABLIM1,NEBL,ATP1A2,SPARCL1,LIFR,MGAT4C,FGFR3,PCDH9,CTNND2,BMPR1B,FMN2
3.150e-04	-8.06	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	15	16828	48	PREX2,EFEMP1,LIFR,NEBL,ATP1A2,NRG3,ATP13A4,ABLIM1,SPARCL1,FGFR3,MGAT4C,CTNND2,FMN2,BMPR1B,PCDH9
3.150e-04	-8.06	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	49	ATP1A2,NTRK2
3.150e-04	-8.06	action potential propagation	biological process	GO:0098870	10	2	18204	49	NTRK2,ATP1A2
3.150e-04	-8.06	cellular response to cocaine	biological process	GO:0071314	10	2	18204	49	SLC1A2,SLC1A3
3.173e-04	-8.06	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	21	16828	48	CTNND2,DPP10,FMN2,TNIK,PCDH9,NFIB,HPSE2,NHSL1,MACF1,GPM6A,SOX5,ADCY2,ABLIM1,NRG3,NEBL,ATP1A2,SPARCL1,ZBTB20,PON2,PTPRZ1,PREX2
3.199e-04	-8.05	middle_third	COSMIC cancer mutations	middle_third	3533	21	16828	48	NFIB,HPSE2,NHSL1,CTNND2,DPP10,FMN2,TNIK,PCDH9,ZBTB20,PON2,PREX2,PTPRZ1,MACF1,SOX5,GPM6A,ADCY2,ABLIM1,NRG3,NEBL,ATP1A2,SPARCL1
3.205e-04	-8.05	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	7	18204	49	PREX2,CTNND2,NFIB,PTPRZ1,GPM6A,TNIK,BMPR1B
3.390e-04	-7.99	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	32	16828	48	GPM6A,SOX5,MACF1,ITPR2,ATP13A4,NRG3,PITPNC1,ZBTB20,PREX2,PTPRZ1,CTNND2,SFXN5,TNIK,PARD3B,FBXL7,FGFR3,NHSL1,SLC1A2,NTM,ADCY2,DTNA,ATP1A2,NEBL,ABLIM1,CDH20,LSAMP,FMN2,QKI,CSGALNACT1,PCDH9,PRKCA,MGAT4C
3.407e-04	-7.98	cell projection morphogenesis	biological process	GO:0048858	496	7	18204	49	CTNND2,PREX2,NFIB,BMPR1B,GPM6A,PTPRZ1,TNIK
3.508e-04	-7.96	ADCY5 (adenylate cyclase 5)	protein interactions	111	11	2	19454	50	PRKCA,ADCY2
3.844e-04	-7.86	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	49	SLC1A3,SLC1A2
3.844e-04	-7.86	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	49	SLC1A3,SLC1A2
3.906e-04	-7.85	regulation of chondrocyte differentiation	biological process	GO:0032330	53	3	18204	49	EFEMP1,SOX5,BMPR1B
3.975e-04	-7.83	NAKATPASE	prints domains	PR00121	9	2	5227	18	ATP1A2,ATP13A4
4.347e-04	-7.74	amino acid transport	biological process	GO:0006865	132	4	18204	49	SLC1A3,NTRK2,SLC1A2,SFXN5
4.404e-04	-7.73	Ig_I-set	interpro domains	IPR013098	132	4	18521	50	NTRK2,LSAMP,NTM,FGFR3
4.462e-04	-7.71	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	13	16828	48	FGFR3,PARD3B,QKI,FMN2,CTNND2,DPP10,CDH20,PTPRZ1,PREX2,LIFR,MACF1,ABLIM1,DTNA
4.462e-04	-7.71	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	13	16828	48	CDH20,PREX2,PTPRZ1,DTNA,ABLIM1,MACF1,LIFR,PARD3B,FGFR3,DPP10,CTNND2,QKI,FMN2
4.466e-04	-7.71	neuron projection	cellular component	GO:0043005	1331	11	19108	49	NFIB,NTRK2,ADCY2,ATP1A2,PCDH9,SLC1A2,CTNND2,BMPR1B,GPM6A,DTNA,SLC1A3
4.633e-04	-7.68	MAD_homology1_Dwarfin-type	interpro domains	IPR003619	12	2	18521	50	NFIB,NFIA
4.733e-04	-7.66	I-set	pfam domains	PF07679	132	4	17795	49	NTRK2,FGFR3,NTM,LSAMP
4.817e-04	-7.64	MH1	pfam domains	PF03165	12	2	17795	49	NFIA,NFIB
5.017e-04	-7.60	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	48	16828	48	PRKCA,SLC1A3,NFIA,FMN2,QKI,CSGALNACT1,CDH20,PON2,NEBL,ATP1A2,LIFR,NTM,NFIB,PARD3B,TNIK,PTPRZ1,GLIS3,NTRK2,PITPNC1,NRG3,ATP13A4,AQP4,SOX5,MACF1,MGAT4C,HPSE2,PCDH9,NPAS3,BMPR1B,LSAMP,DTNA,ABLIM1,SPARCL1,ADCY2,NHSL1,SLC1A2,FBXL7,FGFR3,MSI2,SFXN5,DPP10,CTNND2,ZBTB20,PREX2,EFEMP1,GPM6A,ITPR2,NKAIN3
5.086e-04	-7.58	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	6	10285	28	NTRK2,NRG3,FGFR3,ITPR2,ADCY2,PRKCA
5.187e-04	-7.56	cell junction organization	biological process	GO:0034330	532	7	18204	49	NFIA,PRKCA,CDH20,GPM6A,CTNND2,SPARCL1,NRG3
5.284e-04	-7.55	eye development	biological process	GO:0001654	381	6	18204	49	GPM6A,BMPR1B,NTRK2,EFEMP1,NFIB,NFIA
5.359e-04	-7.53	endochondral bone morphogenesis	biological process	GO:0060350	59	3	18204	49	FGFR3,CSGALNACT1,BMPR1B
5.393e-04	-7.53	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	7	16828	48	NPAS3,LIFR,DPP10,SPARCL1,FGFR3,MGAT4C,ZBTB20
5.432e-04	-7.52	glial cell fate commitment	biological process	GO:0021781	13	2	18204	49	NFIA,NFIB
5.583e-04	-7.49	visual system development	biological process	GO:0150063	385	6	18204	49	GPM6A,BMPR1B,NTRK2,EFEMP1,NFIA,NFIB
5.789e-04	-7.45	GSE1 (Gse1 coiled-coil protein)	protein interactions	23199	149	4	19454	50	SOX5,NFIA,NFIB,TNIK
5.887e-04	-7.44	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	22	16828	48	FMN2,NPAS3,DPP10,CTNND2,PCDH9,TNIK,NFIA,FBXL7,FGFR3,PARD3B,SLC1A2,ADCY2,GPM6A,MACF1,AQP4,NEBL,ATP1A2,PITPNC1,NTRK2,PTPRZ1,PREX2,GLIS3
5.909e-04	-7.43	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	22	16828	48	PCDH9,TNIK,NFIA,NPAS3,FMN2,DPP10,CTNND2,SLC1A2,FBXL7,FGFR3,PARD3B,AQP4,ATP1A2,NEBL,PITPNC1,ADCY2,GPM6A,MACF1,PTPRZ1,PREX2,GLIS3,NTRK2
5.937e-04	-7.43	transmembrane receptor protein tyrosine kinase activity	molecular function	GO:0004714	62	3	18094	48	NTRK2,FGFR3,EFEMP1
6.055e-04	-7.41	sensory system development	biological process	GO:0048880	391	6	18204	49	GPM6A,BMPR1B,NTRK2,EFEMP1,NFIB,NFIA
6.145e-04	-7.39	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	48	SLC1A3,SLC1A2
6.943e-04	-7.27	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_III	249	5	16828	48	PTPRZ1,MGAT4C,GLIS3,FGFR3,MACF1
7.069e-04	-7.25	small_intestine	COSMIC cancer mutations	small_intestine	250	5	16828	48	MACF1,CSGALNACT1,FGFR3,MGAT4C,TNIK
7.136e-04	-7.25	multicellular organismal process	biological process	GO:0032501	6177	28	18204	49	NEBL,AQP4,NRG3,SOX5,NFIB,PREX2,CTNND2,FGFR3,PTPRZ1,ABLIM1,MSI2,SLC1A2,EFEMP1,CDH20,PRKCA,NTRK2,TNIK,PCDH9,DTNA,ATP1A2,NTM,GPM6A,QKI,SLC1A3,CSGALNACT1,LSAMP,NFIA,BMPR1B
7.288e-04	-7.22	exit from mitosis	biological process	GO:0010458	15	2	18204	49	NFIA,NFIB
7.564e-04	-7.19	forebrain development	biological process	GO:0030900	408	6	18204	49	NTRK2,NRG3,ATP1A2,SLC1A2,NFIB,PCDH9
7.650e-04	-7.18	protein kinase activity	molecular function	GO:0004672	577	7	18094	48	MAST4,PRKCA,NTRK2,EFEMP1,FGFR3,TNIK,BMPR1B
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	ZBTB20,LSAMP
8.403e-04	-7.08	gliogenesis	biological process	GO:0042063	275	5	18204	49	NFIA,NFIB,NTRK2,QKI,PTPRZ1
8.541e-04	-7.07	telencephalon development	biological process	GO:0021537	276	5	18204	49	NTRK2,NRG3,ATP1A2,SLC1A2,NFIB
8.605e-04	-7.06	DWA	smart domains	SM00523	12	2	9717	36	NFIB,NFIA
9.985e-04	-6.91	regulation of cartilage development	biological process	GO:0061035	73	3	18204	49	BMPR1B,SOX5,EFEMP1
1.022e-03	-6.89	Htt (huntingtin)	protein interactions	15194	77	3	19454	50	NTM,LSAMP,GPM6A
1.026e-03	-6.88	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	48	SLC1A3,SLC1A2
1.049e-03	-6.86	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	13	19454	50	MSI2,NRG3,PON2,MACF1,PARD3B,DTNA,ZBTB20,NFIA,QKI,ABLIM1,FGFR3,BMPR1B,NFIB
1.063e-03	-6.85	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	2	18521	50	ATP1A2,ATP13A4
1.071e-03	-6.84	astrocyte projection	cellular component	GO:0097449	19	2	19108	49	SLC1A2,AQP4
1.093e-03	-6.82	Bile secretion	KEGG pathways	ko04976	71	3	7161	21	ADCY2,AQP4,ATP1A2
1.093e-03	-6.82	Bile secretion	KEGG pathways	hsa04976	71	3	7161	21	ADCY2,AQP4,ATP1A2
1.101e-03	-6.81	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	40	16828	48	NHSL1,SLC1A2,PARD3B,NFIB,FBXL7,MSI2,TNIK,SFXN5,CTNND2,DPP10,GLIS3,PREX2,PTPRZ1,EFEMP1,NTRK2,NRG3,ATP13A4,ITPR2,NKAIN3,MACF1,SOX5,PRKCA,SLC1A3,HPSE2,NFIA,PCDH9,CSGALNACT1,QKI,NPAS3,FMN2,LSAMP,PON2,CDH20,ABLIM1,ATP1A2,NEBL,SPARCL1,ADCY2,NTM,LIFR
1.101e-03	-6.81	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	40	16828	48	NTRK2,PREX2,EFEMP1,PTPRZ1,GLIS3,SOX5,MACF1,ITPR2,NKAIN3,ATP13A4,NRG3,FBXL7,PARD3B,NFIB,SLC1A2,NHSL1,DPP10,CTNND2,SFXN5,TNIK,MSI2,CDH20,LSAMP,PON2,LIFR,ADCY2,NTM,SPARCL1,ATP1A2,NEBL,ABLIM1,HPSE2,SLC1A3,PRKCA,FMN2,QKI,NPAS3,CSGALNACT1,PCDH9,NFIA
1.105e-03	-6.81	Cation_ATPase_N	pfam domains	PF00690	18	2	17795	49	ATP1A2,ATP13A4
1.131e-03	-6.79	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	9	16828	48	ATP1A2,TNIK,ITPR2,MACF1,BMPR1B,PRKCA,PREX2,NTRK2,FGFR3
1.137e-03	-6.78	animal organ morphogenesis	biological process	GO:0009887	988	9	18204	49	NRG3,SOX5,NFIB,FGFR3,NTRK2,ABLIM1,EFEMP1,CSGALNACT1,BMPR1B
1.143e-03	-6.77	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	8	16828	48	CTNND2,ITPR2,DPP10,SOX5,NEBL,DTNA,NTRK2,SLC1A3
1.158e-03	-6.76	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	6	18204	49	PTPRZ1,BMPR1B,SLC1A3,NFIB,CTNND2,PREX2
1.172e-03	-6.75	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	5	19454	50	DTNA,TNIK,ABLIM1,FMN2,MACF1
1.179e-03	-6.74	cartilage condensation	biological process	GO:0001502	19	2	18204	49	SOX5,BMPR1B
1.210e-03	-6.72	dicarboxylic acid transport	biological process	GO:0006835	78	3	18204	49	SLC1A2,SLC1A3,NTRK2
1.224e-03	-6.71	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	43	16828	48	ATP1A2,NEBL,LIFR,NTM,CDH20,PON2,NFIA,QKI,FMN2,CSGALNACT1,PRKCA,SLC1A3,PITPNC1,ATP13A4,NRG3,SOX5,MACF1,PTPRZ1,GLIS3,NTRK2,TNIK,PARD3B,DTNA,ABLIM1,SPARCL1,ADCY2,LSAMP,PCDH9,NPAS3,BMPR1B,MGAT4C,HPSE2,GPM6A,ITPR2,ZBTB20,PREX2,SFXN5,DPP10,CTNND2,NHSL1,SLC1A2,FBXL7,FGFR3
1.238e-03	-6.69	cervix	COSMIC cancer mutations	cervix	11793	43	16828	48	PARD3B,TNIK,GLIS3,PTPRZ1,NTRK2,NRG3,ATP13A4,PITPNC1,MACF1,SOX5,SLC1A3,PRKCA,NFIA,CSGALNACT1,QKI,FMN2,PON2,CDH20,NEBL,ATP1A2,NTM,LIFR,SLC1A2,NHSL1,FGFR3,FBXL7,SFXN5,CTNND2,DPP10,PREX2,ZBTB20,ITPR2,GPM6A,MGAT4C,HPSE2,PCDH9,BMPR1B,NPAS3,LSAMP,SPARCL1,ABLIM1,DTNA,ADCY2
1.246e-03	-6.69	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	28	16828	48	CDH20,PON2,SPARCL1,ATP1A2,NEBL,DTNA,ABLIM1,ADCY2,SLC1A3,MGAT4C,HPSE2,PCDH9,NFIA,FMN2,PTPRZ1,PREX2,GLIS3,ZBTB20,NTRK2,ATP13A4,NRG3,GPM6A,ITPR2,MACF1,FGFR3,PARD3B,SFXN5,DPP10
1.254e-03	-6.68	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	28	16828	48	FMN2,NFIA,PCDH9,HPSE2,SLC1A3,MGAT4C,ADCY2,NEBL,DTNA,ATP1A2,ABLIM1,SPARCL1,CDH20,PON2,DPP10,SFXN5,PARD3B,FGFR3,GPM6A,ITPR2,MACF1,ATP13A4,NRG3,NTRK2,ZBTB20,PTPRZ1,PREX2,GLIS3
1.307e-03	-6.64	positive regulation of chondrocyte differentiation	biological process	GO:0032332	20	2	18204	49	SOX5,BMPR1B
1.307e-03	-6.64	aspartate transmembrane transport	biological process	GO:0015810	20	2	18204	49	SLC1A3,SLC1A2
1.337e-03	-6.62	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	48	16828	48	PARD3B,NFIB,TNIK,NTRK2,GLIS3,PTPRZ1,MACF1,SOX5,AQP4,ATP13A4,PITPNC1,NRG3,SLC1A3,PRKCA,CSGALNACT1,QKI,FMN2,NFIA,PON2,CDH20,NTM,LIFR,NEBL,ATP1A2,FGFR3,FBXL7,SLC1A2,NHSL1,CTNND2,DPP10,SFXN5,MSI2,PREX2,EFEMP1,ZBTB20,NKAIN3,ITPR2,GPM6A,HPSE2,MGAT4C,BMPR1B,NPAS3,PCDH9,LSAMP,ADCY2,SPARCL1,ABLIM1,DTNA
1.346e-03	-6.61	enzyme-linked receptor protein signaling pathway	biological process	GO:0007167	626	7	18204	49	BMPR1B,EFEMP1,NFIA,NTRK2,LIFR,FGFR3,NRG3
1.397e-03	-6.57	bone	COSMIC cancer mutations	bone	8157	34	16828	48	NEBL,ATP1A2,DTNA,ABLIM1,SPARCL1,LIFR,ADCY2,LSAMP,PON2,PCDH9,FMN2,NPAS3,QKI,CSGALNACT1,SLC1A3,HPSE2,ATP13A4,NRG3,GPM6A,SOX5,NKAIN3,ITPR2,MACF1,ZBTB20,PREX2,PTPRZ1,GLIS3,NTRK2,SFXN5,TNIK,CTNND2,PARD3B,NFIB,FGFR3
1.443e-03	-6.54	cell aggregation	biological process	GO:0098743	21	2	18204	49	BMPR1B,SOX5
1.455e-03	-6.53	ZNF608 (zinc finger protein 608)	protein interactions	57507	87	3	19454	50	SOX5,NFIB,NFIA
1.470e-03	-6.52	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	8	16828	48	PRKCA,NTRK2,FGFR3,TNIK,SOX5,CTNND2,BMPR1B,ADCY2
1.470e-03	-6.52	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	8	16828	48	PRKCA,FGFR3,NTRK2,TNIK,ADCY2,BMPR1B,CTNND2,SOX5
1.518e-03	-6.49	Signalling by NGF	REACTOME pathways	R-HSA-166520	477	6	10285	28	NRG3,NTRK2,ITPR2,FGFR3,PRKCA,ADCY2
1.537e-03	-6.48	Opioid Signalling	REACTOME pathways	R-HSA-111885	85	3	10285	28	ADCY2,ITPR2,PRKCA
1.550e-03	-6.47	Cation_ATPase_N	smart domains	SM00831	16	2	9717	36	ATP13A4,ATP1A2
1.582e-03	-6.45	TIMM10B (translocase of inner mitochondrial membrane 10B)	protein interactions	26515	23	2	19454	50	HPSE2,MSI2
1.582e-03	-6.45	Rbm38 (RNA binding motif protein 38)	protein interactions	56190	23	2	19454	50	MSI2,QKI
1.584e-03	-6.45	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	49	SLC1A3,ATP1A2
1.594e-03	-6.44	DEP_dom	interpro domains	IPR000591	22	2	18521	50	PREX2,FMN2
1.596e-03	-6.44	SHC1 events in ERBB2 signaling	REACTOME pathways	R-HSA-1250196	22	2	10285	28	PRKCA,NRG3
1.603e-03	-6.44	vascular transport	biological process	GO:0010232	86	3	18204	49	SLC1A2,SLC1A3,ATP1A2
1.603e-03	-6.44	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	49	SLC1A2,ATP1A2,SLC1A3
1.659e-03	-6.40	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	3	7161	21	PRKCA,ADCY2,ITPR2
1.659e-03	-6.40	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	3	7161	21	PRKCA,ADCY2,ITPR2
1.664e-03	-6.40	oligodendroglioma_Grade_III	COSMIC cancer mutations	oligodendroglioma_Grade_III	303	5	16828	48	MACF1,FGFR3,PTPRZ1,GLIS3,MGAT4C
1.683e-03	-6.39	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	48	SLC1A2,SLC1A3
1.701e-03	-6.38	adenoma	COSMIC cancer mutations	adenoma	2873	17	16828	48	NEBL,LIFR,ADCY2,SOX5,GPM6A,MACF1,PTPRZ1,CDH20,ZBTB20,NTRK2,PCDH9,NPAS3,BMPR1B,CTNND2,PRKCA,HPSE2,FGFR3
1.715e-03	-6.37	human chr17q24.2	chromosome location	human chr17q24.2	32	2	26134	50	PRKCA,PITPNC1
1.724e-03	-6.36	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	19	16828	48	PREX2,EFEMP1,PTPRZ1,GLIS3,MACF1,ITPR2,LIFR,ADCY2,NEBL,ATP1A2,NRG3,ATP13A4,PITPNC1,FGFR3,PRKCA,MGAT4C,CTNND2,FMN2,PCDH9
1.745e-03	-6.35	RNA Polymerase III Transcription Termination	REACTOME pathways	R-HSA-73980	23	2	10285	28	NFIB,NFIA
1.758e-03	-6.34	cell development	biological process	GO:0048468	2236	14	18204	49	MSI2,NTM,GPM6A,QKI,NEBL,CTNND2,PREX2,NFIB,PTPRZ1,NTRK2,TNIK,FMN2,BMPR1B,SLC1A3
1.776e-03	-6.33	Prot_kinase_dom	interpro domains	IPR000719	480	6	18521	50	PRKCA,TNIK,MAST4,BMPR1B,NTRK2,FGFR3
1.784e-03	-6.33	extremity	COSMIC cancer mutations	extremity	1876	13	16828	48	FGFR3,FBXL7,HPSE2,FMN2,PCDH9,NTRK2,CDH20,PTPRZ1,PREX2,ADCY2,PITPNC1,ATP13A4,NEBL
1.817e-03	-6.31	WWC1 (WW and C2 domain containing 1)	protein interactions	23286	94	3	19454	50	PRKCA,ABLIM1,TNIK
1.817e-03	-6.31	FOXP4 (forkhead box P4)	protein interactions	116113	94	3	19454	50	SOX5,NFIA,NFIB
1.817e-03	-6.31	GRIN1 (glutamate ionotropic receptor NMDA type subunit 1)	protein interactions	2902	94	3	19454	50	NTRK2,FGFR3,PRKCA
1.824e-03	-6.31	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	16	16828	48	FMN2,CSGALNACT1,CTNND2,PCDH9,HPSE2,FGFR3,SLC1A2,NHSL1,ADCY2,SOX5,ATP1A2,NRG3,NTRK2,EFEMP1,PTPRZ1,ZBTB20
1.829e-03	-6.30	ear	COSMIC cancer mutations	ear	624	7	16828	48	MGAT4C,SPARCL1,ZBTB20,FGFR3,LIFR,NPAS3,DPP10
1.832e-03	-6.30	P-type ion transporter activity	molecular function	GO:0015662	24	2	18094	48	ATP13A4,ATP1A2
1.832e-03	-6.30	P-type transmembrane transporter activity	molecular function	GO:0140358	24	2	18094	48	ATP13A4,ATP1A2
1.840e-03	-6.30	Insulin secretion	KEGG pathways	hsa04911	85	3	7161	21	ATP1A2,PRKCA,ADCY2
1.901e-03	-6.27	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	28	SLC1A3,SLC1A2
1.913e-03	-6.26	human chr9p23-p22.3	chromosome location	human chr9p23-p22.3	1	1	26134	50	NFIB
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.913e-03	-6.26	human chr12q21.31-q21.32	chromosome location	human chr12q21.31-q21.32	1	1	26134	50	MGAT4C
1.940e-03	-6.25	skin-face-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-face-malignant_melanoma-lentigo_maligna	23	2	16828	48	PREX2,FGFR3
1.960e-03	-6.23	synapse organization	biological process	GO:0050808	333	5	18204	49	GPM6A,NFIA,CTNND2,SPARCL1,NRG3
1.970e-03	-6.23	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	16	16828	48	DPP10,CTNND2,PCDH9,HPSE2,SLC1A3,MGAT4C,LIFR,SOX5,ATP1A2,NEBL,ATP13A4,NRG3,PREX2,CDH20,PTPRZ1,LSAMP
2.023e-03	-6.20	ETV7 (ETS variant transcription factor 7)	protein interactions	51513	26	2	19454	50	NFIA,NFIB
2.032e-03	-6.20	Gap junction	KEGG pathways	hsa04540	88	3	7161	21	ADCY2,PRKCA,ITPR2
2.032e-03	-6.20	Gap junction	KEGG pathways	ko04540	88	3	7161	21	ADCY2,PRKCA,ITPR2
2.047e-03	-6.19	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	49	SLC1A2,SLC1A3
2.077e-03	-6.18	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	7	18094	48	NTRK2,EFEMP1,PRKCA,FGFR3,TNIK,BMPR1B,MAST4
2.141e-03	-6.15	skeletal system development	biological process	GO:0001501	500	6	18204	49	NFIA,CSGALNACT1,BMPR1B,FGFR3,NFIB,SOX5
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	ABLIM1,DTNA
2.181e-03	-6.13	MBNL2 (muscleblind like splicing regulator 2)	protein interactions	10150	27	2	19454	50	MSI2,QKI
2.181e-03	-6.13	HPCAL4 (hippocalcin like 4)	protein interactions	51440	27	2	19454	50	AQP4,GPM6A
2.185e-03	-6.13	LYN (LYN proto-oncogene, Src family tyrosine kinase)	protein interactions	4067	713	7	19454	50	ABLIM1,FMN2,MSI2,TNIK,DTNA,MACF1,SLC1A3
2.200e-03	-6.12	EZR (ezrin)	protein interactions	7430	526	6	19454	50	DTNA,TNIK,ABLIM1,PRKCA,NEBL,MACF1
2.206e-03	-6.12	protein phosphorylation	biological process	GO:0006468	503	6	18204	49	MAST4,BMPR1B,TNIK,EFEMP1,PRKCA,NTRK2
2.214e-03	-6.11	C4-dicarboxylate transport	biological process	GO:0015740	26	2	18204	49	SLC1A2,SLC1A3
2.214e-03	-6.11	regulation of macrophage differentiation	biological process	GO:0045649	26	2	18204	49	PRKCA,QKI
2.285e-03	-6.08	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	7	16828	48	NFIB,MACF1,QKI,FGFR3,ABLIM1,PREX2,TNIK
2.308e-03	-6.07	GnRH signaling pathway	KEGG pathways	ko04912	92	3	7161	21	ADCY2,PRKCA,ITPR2
2.308e-03	-6.07	GnRH signaling pathway	KEGG pathways	hsa04912	92	3	7161	21	ADCY2,PRKCA,ITPR2
2.342e-03	-6.06	Downstream signal transduction	REACTOME pathways	R-HSA-186763	352	5	10285	28	NRG3,ADCY2,FGFR3,ITPR2,PRKCA
2.365e-03	-6.05	Calcium-transporting ATPase, transmembrane domain	gene3d domains	1.20.1110.10	25	2	14470	42	ATP13A4,ATP1A2
2.393e-03	-6.04	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	22	16828	48	PREX2,PTPRZ1,PON2,GLIS3,DTNA,ATP1A2,ABLIM1,NRG3,LIFR,ADCY2,GPM6A,SOX5,MACF1,SLC1A3,MGAT4C,NHSL1,FGFR3,PCDH9,FMN2,QKI,DPP10,CTNND2
2.393e-03	-6.04	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	22	16828	48	CTNND2,DPP10,NHSL1,FGFR3,NRG3,MACF1,SOX5,GPM6A,GLIS3,PREX2,PTPRZ1,PCDH9,QKI,FMN2,MGAT4C,SLC1A3,ABLIM1,DTNA,ATP1A2,ADCY2,LIFR,PON2
2.398e-03	-6.03	bone morphogenesis	biological process	GO:0060349	99	3	18204	49	BMPR1B,CSGALNACT1,FGFR3
2.401e-03	-6.03	neuron projection development	biological process	GO:0031175	693	7	18204	49	PREX2,CTNND2,NFIB,PTPRZ1,GPM6A,TNIK,BMPR1B
2.461e-03	-6.01	DAP12 signaling	REACTOME pathways	R-HSA-2424491	356	5	10285	28	FGFR3,ITPR2,ADCY2,PRKCA,NRG3
2.495e-03	-5.99	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	6	16828	48	PRKCA,TNIK,NTRK2,MACF1,BMPR1B,FGFR3
2.545e-03	-5.97	lung-carcinoma-large_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-large_cell_carcinoma	849	8	16828	48	BMPR1B,FGFR3,LIFR,NTRK2,DPP10,TNIK,PTPRZ1,PRKCA
2.545e-03	-5.97	large_cell_carcinoma	COSMIC cancer mutations	large_cell_carcinoma	849	8	16828	48	NTRK2,DPP10,FGFR3,BMPR1B,LIFR,PRKCA,TNIK,PTPRZ1
2.564e-03	-5.97	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	17	16828	48	ATP1A2,NEBL,NRG3,SPARCL1,MACF1,LIFR,NTM,ADCY2,PON2,NTRK2,MSI2,DPP10,NPAS3,FMN2,BMPR1B,PRKCA,FGFR3
2.564e-03	-5.97	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	17	16828	48	MSI2,BMPR1B,NPAS3,FMN2,DPP10,PRKCA,FGFR3,SPARCL1,NRG3,NEBL,ATP1A2,ADCY2,NTM,LIFR,MACF1,PON2,NTRK2
2.566e-03	-5.97	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	49	QKI,PTPRZ1
2.566e-03	-5.97	glial cell proliferation	biological process	GO:0014009	28	2	18204	49	NFIA,NFIB
2.570e-03	-5.96	Agtrap (angiotensin II, type I receptor-associated protein)	protein interactions	11610	1	1	19454	50	PITPNC1
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	TAS2R20 (taste 2 receptor member 20)	protein interactions	259295	1	1	19454	50	PRKCA
2.570e-03	-5.96	fbxw7.L (F-box and WD repeat domain containing 7 L homeolog)	protein interactions	734230	1	1	19454	50	PRKCA
2.570e-03	-5.96	Sh2b1 (SH2B adaptor protein 1)	protein interactions	20399	1	1	19454	50	FGFR3
2.570e-03	-5.96	Lztr1 (leucine-zipper-like transcriptional regulator, 1)	protein interactions	66863	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	1700006A11Rik (RIKEN cDNA 1700006A11 gene)	protein interactions	71824	1	1	19454	50	BMPR1B
2.570e-03	-5.96	Dcaf7 (DDB1 and CUL4 associated factor 7)	protein interactions	71833	1	1	19454	50	BMPR1B
2.570e-03	-5.96	fgf3.L (fibroblast growth factor 3 L homeolog)	protein interactions	373669	1	1	19454	50	FGFR3
2.585e-03	-5.96	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	11	16828	48	MACF1,FMN2,NPAS3,NRG3,DTNA,PCDH9,PARD3B,FGFR3,EFEMP1,PTPRZ1,PREX2
2.586e-03	-5.96	CaM pathway	REACTOME pathways	R-HSA-111997	28	2	10285	28	ADCY2,PRKCA
2.586e-03	-5.96	Calmodulin induced events	REACTOME pathways	R-HSA-111933	28	2	10285	28	ADCY2,PRKCA
2.603e-03	-5.95	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	4	19454	50	ABLIM1,GPM6A,MACF1,MAST4
2.620e-03	-5.94	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	7	16828	48	TNIK,SPARCL1,PRKCA,FGFR3,BMPR1B,LIFR,NTRK2
2.625e-03	-5.94	non_seminoma	COSMIC cancer mutations	non_seminoma	492	6	16828	48	MACF1,NTRK2,FGFR3,BMPR1B,PRKCA,TNIK
2.652e-03	-5.93	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	4	10285	28	ADCY2,SLC1A2,PRKCA,SLC1A3
2.653e-03	-5.93	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	48	QKI
2.653e-03	-5.93	ethanolamine-phosphate phospho-lyase activity	molecular function	GO:0050459	1	1	18094	48	ETNPPL
2.653e-03	-5.93	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	48	NTRK2
2.653e-03	-5.93	peptidoglycan glycosyltransferase activity	molecular function	GO:0008955	1	1	18094	48	CSGALNACT1
2.673e-03	-5.92	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	48	SLC1A3,SLC1A2
2.685e-03	-5.92	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	3	7161	21	ADCY2,PRKCA,ITPR2
2.685e-03	-5.92	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	3	7161	21	ITPR2,ADCY2,PRKCA
2.692e-03	-5.92	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	49	ATP1A2
2.692e-03	-5.92	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological process	GO:0051758	1	1	18204	49	FMN2
2.692e-03	-5.92	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	49	NRG3
2.692e-03	-5.92	negative regulation of epithelial cell proliferation involved in lung morphogenesis	biological process	GO:2000795	1	1	18204	49	NFIB
2.692e-03	-5.92	olfactory cortex development	biological process	GO:0021989	1	1	18204	49	ATP1A2
2.692e-03	-5.92	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	49	NRG3
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	49	NTRK2
2.692e-03	-5.92	lung ciliated cell differentiation	biological process	GO:0061141	1	1	18204	49	NFIB
2.692e-03	-5.92	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	49	NTRK2
2.692e-03	-5.92	positive regulation of angiotensin-activated signaling pathway	biological process	GO:0110063	1	1	18204	49	PRKCA
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	Nebulette_SH3	interpro domains	IPR035631	1	1	18521	50	NEBL
2.700e-03	-5.91	cPKC_alpha	interpro domains	IPR034663	1	1	18521	50	PRKCA
2.700e-03	-5.91	Rex2_DEP_1	interpro domains	IPR037367	1	1	18521	50	PREX2
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	LIFR_N	interpro domains	IPR040901	1	1	18521	50	LIFR
2.709e-03	-5.91	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	7	16828	48	TNIK,SPARCL1,BMPR1B,LIFR,PRKCA,FGFR3,NTRK2
2.711e-03	-5.91	Signaling by EGFR	REACTOME pathways	R-HSA-177929	364	5	10285	28	ITPR2,FGFR3,ADCY2,PRKCA,NRG3
2.718e-03	-5.91	NR3C1 (nuclear receptor subfamily 3 group C member 1)	protein interactions	2908	950	8	19454	50	SLC1A3,PON2,ZBTB20,NFIA,ATP13A4,NFIB,ADCY2,CTNND2
2.722e-03	-5.91	t(4;14) translocations of FGFR3	REACTOME pathways	R-HSA-2033515	1	1	10285	28	FGFR3
2.723e-03	-5.91	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	6	14470	42	MAST4,NTRK2,PRKCA,FGFR3,TNIK,BMPR1B
2.730e-03	-5.90	Kinase-like_dom_sf	interpro domains	IPR011009	523	6	18521	50	TNIK,PRKCA,MAST4,NTRK2,BMPR1B,FGFR3
2.754e-03	-5.89	LIFR_N	pfam domains	PF18207	1	1	17795	49	LIFR
2.754e-03	-5.89	FGFR3_TM	pfam domains	PF21165	1	1	17795	49	FGFR3
2.754e-03	-5.89	Quaking_NLS	pfam domains	PF16551	1	1	17795	49	QKI
2.754e-03	-5.89	STAR_dimer	pfam domains	PF16544	1	1	17795	49	QKI
2.834e-03	-5.87	neural precursor cell proliferation	biological process	GO:0061351	105	3	18204	49	SOX5,NFIB,NFIA
2.853e-03	-5.86	MKRN2 (makorin ring finger protein 2)	protein interactions	23609	380	5	19454	50	PRKCA,FGFR3,MACF1,BMPR1B,NFIB
2.857e-03	-5.86	cell body	cellular component	GO:0044297	556	6	19108	49	ATP1A2,SLC1A2,CTNND2,BMPR1B,GPM6A,SLC1A3
2.862e-03	-5.86	ACTB (actin beta)	protein interactions	60	958	8	19454	50	FMN2,NEBL,SFXN5,ABLIM1,PRKCA,MACF1,NHSL1,DTNA
2.870e-03	-5.85	SH2B1 (SH2B adaptor protein 1)	protein interactions	25970	31	2	19454	50	NTRK2,FGFR3
2.870e-03	-5.85	AVPR1B (arginine vasopressin receptor 1B)	protein interactions	553	31	2	19454	50	FMN2,PRKCA
2.872e-03	-5.85	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	13	16828	48	PTPRZ1,ZBTB20,LIFR,SOX5,ATP1A2,PARD3B,NHSL1,CSGALNACT1,BMPR1B,QKI,FMN2,CTNND2,DPP10
2.872e-03	-5.85	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	13	16828	48	NHSL1,PARD3B,DPP10,CTNND2,QKI,FMN2,BMPR1B,CSGALNACT1,ZBTB20,PTPRZ1,ATP1A2,SOX5,LIFR
2.903e-03	-5.84	-	gene3d domains	6.10.250.1740	1	1	14470	42	FGFR3
2.903e-03	-5.84	-	gene3d domains	1.20.5.4010	1	1	14470	42	QKI
2.931e-03	-5.83	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	26	16828	48	PTPRZ1,NTRK2,ATP13A4,NRG3,MACF1,ITPR2,NKAIN3,GPM6A,SOX5,PARD3B,FBXL7,CTNND2,DPP10,LSAMP,CDH20,DTNA,NEBL,ATP1A2,NTM,ADCY2,LIFR,MGAT4C,SLC1A3,HPSE2,FMN2,NPAS3
2.931e-03	-5.83	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	26	16828	48	DPP10,CTNND2,FBXL7,PARD3B,GPM6A,SOX5,ITPR2,NKAIN3,MACF1,NRG3,ATP13A4,NTRK2,PTPRZ1,FMN2,NPAS3,HPSE2,SLC1A3,MGAT4C,LIFR,NTM,ADCY2,ATP1A2,NEBL,DTNA,CDH20,LSAMP
2.942e-03	-5.83	L-glutamate import	biological process	GO:0051938	30	2	18204	49	SLC1A2,SLC1A3
2.944e-03	-5.83	DAP12 interactions	REACTOME pathways	R-HSA-2172127	371	5	10285	28	PRKCA,FGFR3,ITPR2,ADCY2,NRG3
2.952e-03	-5.83	cellular response to endogenous stimulus	biological process	GO:0071495	1135	9	18204	49	BMPR1B,SLC1A2,NFIA,ATP1A2,NTRK2,ITPR2,FGFR3,SLC1A3,SOX5
2.966e-03	-5.82	Ca-dependent events	REACTOME pathways	R-HSA-111996	30	2	10285	28	PRKCA,ADCY2
2.991e-03	-5.81	TBR1 (T-box brain transcription factor 1)	protein interactions	10716	112	3	19454	50	NFIB,NFIA,SOX5
3.012e-03	-5.81	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	3	7161	21	PRKCA,ADCY2,ITPR2
3.012e-03	-5.81	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	3	7161	21	ITPR2,ADCY2,PRKCA
3.046e-03	-5.79	HMG20A (high mobility group 20A)	protein interactions	10363	234	4	19454	50	DTNA,SOX5,NFIA,NFIB
3.119e-03	-5.77	Signaling by PDGF	REACTOME pathways	R-HSA-186797	376	5	10285	28	PRKCA,ADCY2,FGFR3,ITPR2,NRG3
3.140e-03	-5.76	endochondral ossification	biological process	GO:0001958	31	2	18204	49	FGFR3,CSGALNACT1
3.140e-03	-5.76	replacement ossification	biological process	GO:0036075	31	2	18204	49	FGFR3,CSGALNACT1
3.144e-03	-5.76	ORF3b (ORF3b protein)	protein interactions	1489670	114	3	19454	50	ZBTB20,MACF1,PCDH9
3.145e-03	-5.76	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	47	16828	48	MACF1,SOX5,AQP4,ATP13A4,NRG3,PITPNC1,NTRK2,GLIS3,PTPRZ1,TNIK,NFIB,PARD3B,NTM,LIFR,NEBL,ATP1A2,PON2,CDH20,CSGALNACT1,QKI,FMN2,NFIA,SLC1A3,PRKCA,NKAIN3,ITPR2,GPM6A,EFEMP1,PREX2,ZBTB20,CTNND2,DPP10,SFXN5,FGFR3,FBXL7,SLC1A2,NHSL1,ADCY2,SPARCL1,ABLIM1,DTNA,LSAMP,BMPR1B,NPAS3,PCDH9,HPSE2,MGAT4C
3.152e-03	-5.76	kinase activity	molecular function	GO:0016301	739	7	18094	48	PRKCA,MAST4,BMPR1B,TNIK,EFEMP1,FGFR3,NTRK2
3.185e-03	-5.75	phosphorylation	biological process	GO:0016310	729	7	18204	49	TNIK,BMPR1B,MAST4,NTRK2,PRKCA,FGFR3,EFEMP1
3.259e-03	-5.73	caecum	COSMIC cancer mutations	caecum	14248	47	16828	48	HPSE2,MGAT4C,BMPR1B,NPAS3,PCDH9,LSAMP,ADCY2,ABLIM1,DTNA,SPARCL1,FGFR3,FBXL7,NHSL1,SLC1A2,CTNND2,DPP10,SFXN5,ZBTB20,PREX2,EFEMP1,ITPR2,NKAIN3,GPM6A,PRKCA,SLC1A3,CSGALNACT1,FMN2,QKI,NFIA,PON2,CDH20,NTM,LIFR,ATP1A2,NEBL,NFIB,PARD3B,TNIK,NTRK2,GLIS3,PTPRZ1,MACF1,SOX5,ATP13A4,NRG3,PITPNC1,AQP4
3.266e-03	-5.72	skeletal system morphogenesis	biological process	GO:0048705	228	4	18204	49	CSGALNACT1,FGFR3,SOX5,BMPR1B
3.282e-03	-5.72	E1-E2_ATPase	pfam domains	PF00122	31	2	17795	49	ATP1A2,ATP13A4
3.293e-03	-5.72	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	3	10285	28	ADCY2,ITPR2,PRKCA
3.294e-03	-5.72	skin-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-malignant_melanoma-acral_lentiginous	30	2	16828	48	FGFR3,PREX2
3.294e-03	-5.72	lentigo_maligna	COSMIC cancer mutations	lentigo_maligna	30	2	16828	48	PREX2,FGFR3
3.336e-03	-5.70	GJA1 (gap junction protein alpha 1)	protein interactions	2697	572	6	19454	50	ITPR2,MACF1,PRKCA,PCDH9,TNIK,DTNA
3.344e-03	-5.70	transepithelial transport	biological process	GO:0070633	32	2	18204	49	SLC1A3,SLC1A2
3.344e-03	-5.70	positive regulation of cartilage development	biological process	GO:0061036	32	2	18204	49	SOX5,BMPR1B
3.401e-03	-5.68	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	5	18521	50	FGFR3,BMPR1B,PRKCA,NTRK2,TNIK
3.403e-03	-5.68	cell adhesion	biological process	GO:0007155	942	8	18204	49	CDH20,NTM,PRKCA,LSAMP,PCDH9,PARD3B,SPARCL1,CTNND2
3.444e-03	-5.67	AQUAPORIN4	prints domains	PR02016	1	1	5227	18	AQP4
3.444e-03	-5.67	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	18	NTRK2
3.472e-03	-5.66	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	7	18094	48	SLC1A2,ATP1A2,GPM6A,ITPR2,SFXN5,ATP13A4,SLC1A3
3.495e-03	-5.66	Cation_ATPase	pfam domains	PF13246	32	2	17795	49	ATP1A2,ATP13A4
3.553e-03	-5.64	response to auditory stimulus	biological process	GO:0010996	33	2	18204	49	SLC1A3,ATP1A2
3.649e-03	-5.61	TPRA1 (transmembrane protein adipocyte associated 1)	protein interactions	131601	35	2	19454	50	ITPR2,BMPR1B
3.705e-03	-5.60	DELLA	smart domains	SM01129	1	1	9717	36	MACF1
3.714e-03	-5.60	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	9	16828	48	FGFR3,MGAT4C,PREX2,ADCY2,NTM,LIFR,MACF1,CTNND2,ATP13A4
3.742e-03	-5.59	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	45	16828	48	QKI,FMN2,CSGALNACT1,NFIA,SLC1A3,PRKCA,LIFR,NTM,NEBL,ATP1A2,CDH20,TNIK,NFIB,PARD3B,SOX5,MACF1,ATP13A4,NRG3,PITPNC1,NTRK2,PTPRZ1,GLIS3,NPAS3,BMPR1B,PCDH9,HPSE2,MGAT4C,ADCY2,DTNA,ABLIM1,LSAMP,DPP10,CTNND2,SFXN5,MSI2,FBXL7,FGFR3,SLC1A2,NHSL1,GPM6A,NKAIN3,ITPR2,EFEMP1,PREX2,ZBTB20
3.749e-03	-5.59	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	4	19454	50	SOX5,NFIA,NFIB,TNIK
3.760e-03	-5.58	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	4	16828	48	CTNND2,BMPR1B,PRKCA,PCDH9
3.815e-03	-5.57	metal ion binding	molecular function	GO:0046872	4239	20	18094	48	ABLIM1,MGAT4C,ADCY2,SLC1A3,ITPR2,MAST4,MACF1,ATP1A2,PCDH9,PRKCA,EFEMP1,ATP13A4,PON2,CSGALNACT1,ZBTB20,GLIS3,DTNA,SLC1A2,SPARCL1,BMPR1B
3.858e-03	-5.56	receptor complex	cellular component	GO:0043235	409	5	19108	49	BMPR1B,FGFR3,ITPR2,LIFR,NTRK2
3.878e-03	-5.55	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	48	SLC1A3,SLC1A2
3.912e-03	-5.54	Ig_sub2	interpro domains	IPR003598	239	4	18521	50	NTM,FGFR3,NTRK2,LSAMP
3.979e-03	-5.53	glutamatergic synapse	cellular component	GO:0098978	412	5	19108	49	TNIK,NRG3,SPARCL1,GPM6A,SLC1A2
3.990e-03	-5.52	neuron fate specification	biological process	GO:0048665	35	2	18204	49	NFIA,NFIB
4.034e-03	-5.51	Cholinergic synapse	KEGG pathways	hsa04725	112	3	7161	21	PRKCA,ADCY2,ITPR2
4.052e-03	-5.51	glial cell projection	cellular component	GO:0097386	37	2	19108	49	AQP4,SLC1A2
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	QKI,ZBTB20
4.071e-03	-5.50	PADI3 (peptidyl arginine deiminase 3)	protein interactions	51702	37	2	19454	50	SPARCL1,CSGALNACT1
4.094e-03	-5.50	transporter activity	molecular function	GO:0005215	1211	9	18094	48	PITPNC1,SLC1A3,ATP13A4,SFXN5,ITPR2,SLC1A2,AQP4,ATP1A2,GPM6A
4.196e-03	-5.47	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III	114	3	16828	48	SOX5,SLC1A2,PREX2
4.217e-03	-5.47	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	48	QKI,FGFR3
4.244e-03	-5.46	ATPase_P-typ_transduc_dom_A_sf	interpro domains	IPR008250	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	ATPase_P-typ_cyto_dom_N	interpro domains	IPR023299	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	ATPase_P-typ_P_site	interpro domains	IPR018303	36	2	18521	50	ATP13A4,ATP1A2
4.244e-03	-5.46	P_typ_ATPase_HD_dom	interpro domains	IPR044492	36	2	18521	50	ATP1A2,ATP13A4
4.244e-03	-5.46	P_typ_ATPase	interpro domains	IPR001757	36	2	18521	50	ATP13A4,ATP1A2
4.258e-03	-5.46	EPB41L4A (erythrocyte membrane protein band 4.1 like 4A)	protein interactions	64097	127	3	19454	50	DTNA,ABLIM1,MACF1
4.258e-03	-5.46	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	50	QKI,NFIB,NFIA
4.281e-03	-5.45	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	49	NTRK2,MACF1,PTPRZ1,QKI
4.290e-03	-5.45	Pcbp1 (poly(rC) binding protein 1)	protein interactions	23983	38	2	19454	50	MSI2,QKI
4.342e-03	-5.44	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	6	16828	48	FGFR3,BMPR1B,FMN2,NTRK2,TNIK,PRKCA
4.380e-03	-5.43	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	6	16828	48	FGFR3,BMPR1B,FMN2,NTRK2,TNIK,PRKCA
4.432e-03	-5.42	chondroitin biosynthesis	BIOCYC pathways	HUMAN_PWY-6566	2	1	902	2	CSGALNACT1
4.448e-03	-5.42	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	3	19454	50	ABLIM1,ZBTB20,ITPR2
4.449e-03	-5.42	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	6	12186	40	MAST4,PRKCA,BMPR1B,TNIK,FGFR3,NTRK2
4.478e-03	-5.41	ATPase_P-typ_TM_dom_sf	interpro domains	IPR023298	37	2	18521	50	ATP1A2,ATP13A4
4.487e-03	-5.41	testis	COSMIC cancer mutations	testis	733	7	16828	48	NTRK2,FGFR3,PRKCA,PREX2,MACF1,BMPR1B,TNIK
4.491e-03	-5.41	sensory organ development	biological process	GO:0007423	581	6	18204	49	NFIB,EFEMP1,NFIA,NTRK2,BMPR1B,GPM6A
4.563e-03	-5.39	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	5	16828	48	TNIK,PRKCA,FGFR3,LIFR,NTRK2
4.563e-03	-5.39	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	5	16828	48	PRKCA,TNIK,NTRK2,LIFR,FGFR3
4.563e-03	-5.39	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	5	16828	48	TNIK,PRKCA,LIFR,FGFR3,NTRK2
4.563e-03	-5.39	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	5	16828	48	PRKCA,TNIK,NTRK2,FGFR3,LIFR
4.563e-03	-5.39	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	5	16828	48	TNIK,PRKCA,LIFR,FGFR3,NTRK2
4.643e-03	-5.37	ZNF609 (zinc finger protein 609)	protein interactions	23060	131	3	19454	50	NFIA,NFIB,SOX5
4.643e-03	-5.37	TRPS1 (transcriptional repressor GATA binding 1)	protein interactions	7227	131	3	19454	50	NFIB,NFIA,SOX5
4.691e-03	-5.36	amino acid import across plasma membrane	biological process	GO:0089718	38	2	18204	49	SLC1A3,SLC1A2
4.715e-03	-5.36	spindle	COSMIC cancer mutations	spindle	386	5	16828	48	CTNND2,MACF1,FGFR3,PREX2,PCDH9
4.718e-03	-5.36	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	48	FGFR3,QKI
4.868e-03	-5.33	Calcium-transporting ATPase, cytoplasmic transduction domain A	gene3d domains	2.70.150.10	36	2	14470	42	ATP1A2,ATP13A4
4.868e-03	-5.33	Calcium-transporting ATPase, cytoplasmic domain N	gene3d domains	3.40.1110.10	36	2	14470	42	ATP1A2,ATP13A4
4.868e-03	-5.33	dendrite	cellular component	GO:0030425	620	6	19108	49	GPM6A,BMPR1B,CTNND2,ATP1A2,ADCY2,NTRK2
4.901e-03	-5.32	acral_lentiginous	COSMIC cancer mutations	acral_lentiginous	745	7	16828	48	MACF1,CSGALNACT1,ATP13A4,NRG3,FGFR3,CDH20,PREX2
4.904e-03	-5.32	phosphorus metabolic process	biological process	GO:0006793	1707	11	18204	49	PTPRZ1,ADCY2,FGFR3,BMPR1B,MAST4,TNIK,EFEMP1,CSGALNACT1,NTRK2,ATP1A2,PRKCA
4.918e-03	-5.31	cell differentiation	biological process	GO:0030154	3645	18	18204	49	BMPR1B,TNIK,FMN2,NFIA,NTRK2,SLC1A3,QKI,GPM6A,NTM,MSI2,NHSL1,PTPRZ1,NFIB,PREX2,CTNND2,FGFR3,NEBL,SOX5
4.930e-03	-5.31	VEGFR2 mediated cell proliferation	REACTOME pathways	R-HSA-5218921	258	4	10285	28	NRG3,PRKCA,ITPR2,FGFR3
4.936e-03	-5.31	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	49	SLC1A2,SLC1A3
4.936e-03	-5.31	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	49	ATP1A2,SLC1A3
4.944e-03	-5.31	dendritic tree	cellular component	GO:0097447	622	6	19108	49	CTNND2,BMPR1B,GPM6A,ADCY2,NTRK2,ATP1A2
4.955e-03	-5.31	oligoastrocytoma_Grade_II	COSMIC cancer mutations	oligoastrocytoma_Grade_II	121	3	16828	48	FGFR3,DTNA,CDH20
4.963e-03	-5.31	cellular developmental process	biological process	GO:0048869	3648	18	18204	49	SLC1A3,TNIK,FMN2,BMPR1B,NTRK2,NFIA,PTPRZ1,NHSL1,NEBL,SOX5,NFIB,CTNND2,PREX2,FGFR3,GPM6A,QKI,NTM,MSI2
4.979e-03	-5.30	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	48	FGFR3,QKI
5.012e-03	-5.30	Vascular smooth muscle contraction	KEGG pathways	ko04270	121	3	7161	21	ITPR2,ADCY2,PRKCA
5.012e-03	-5.30	Vascular smooth muscle contraction	KEGG pathways	hsa04270	121	3	7161	21	ITPR2,ADCY2,PRKCA
5.049e-03	-5.29	FOXP1 (forkhead box P1)	protein interactions	27086	135	3	19454	50	SOX5,NFIA,NFIB
5.049e-03	-5.29	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	3	19454	50	NTRK2,DTNA,ABLIM1
5.090e-03	-5.28	cation binding	molecular function	GO:0043169	4341	20	18094	48	ABLIM1,ADCY2,MGAT4C,SLC1A3,ITPR2,MAST4,MACF1,ATP1A2,PCDH9,PRKCA,EFEMP1,PON2,ATP13A4,CSGALNACT1,ZBTB20,GLIS3,DTNA,SLC1A2,BMPR1B,SPARCL1
5.127e-03	-5.27	RHOB (ras homolog family member B)	protein interactions	388	832	7	19454	50	TNIK,ABLIM1,DTNA,PARD3B,MACF1,SLC1A3,FMN2
5.128e-03	-5.27	Aldosterone-regulated sodium reabsorption	KEGG pathways	hsa04960	37	2	7161	21	PRKCA,ATP1A2
5.128e-03	-5.27	Aldosterone-regulated sodium reabsorption	KEGG pathways	ko04960	37	2	7161	21	PRKCA,ATP1A2
5.134e-03	-5.27	Bmpr2 (bone morphogenetic protein receptor type 2)	protein interactions	12168	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1b (FK506 binding protein 1b)	protein interactions	14226	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fkbp1a (FK506 binding protein 1a)	protein interactions	14225	2	1	19454	50	BMPR1B
5.134e-03	-5.27	numb (numb)	protein interactions	34263	2	1	19454	50	PRKCA
5.134e-03	-5.27	Grin2c (glutamate ionotropic receptor NMDA type subunit 2C)	protein interactions	24411	2	1	19454	50	PRKCA
5.134e-03	-5.27	Klhl1 (kelch-like 1)	protein interactions	93688	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Ppp3cc (protein phosphatase 3, catalytic subunit, gamma isoform)	protein interactions	19057	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Fbxo34 (F-box protein 34)	protein interactions	78938	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Irf7 (interferon regulatory factor 7)	protein interactions	54123	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Sh3kbp1 (SH3-domain kinase binding protein 1)	protein interactions	58194	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Mknk2 (MAP kinase-interacting serine/threonine kinase 2)	protein interactions	17347	2	1	19454	50	BMPR1B
5.134e-03	-5.27	Bcr (BCR activator of RhoGEF and GTPase)	protein interactions	110279	2	1	19454	50	BMPR1B
5.198e-03	-5.26	RDX (radixin)	protein interactions	5962	272	4	19454	50	ABLIM1,NEBL,MACF1,FGFR3
5.220e-03	-5.26	GRIA2 (glutamate ionotropic receptor AMPA type subunit 2)	protein interactions	2891	42	2	19454	50	PRKCA,GPM6A
5.238e-03	-5.25	ion binding	molecular function	GO:0043167	6007	25	18094	48	ATP13A4,PON2,EFEMP1,PCDH9,TNIK,CSGALNACT1,ZBTB20,GLIS3,ETNPPL,ADCY2,FGFR3,ATP1A2,MAST4,ITPR2,MACF1,NTRK2,PRKCA,PITPNC1,SPARCL1,BMPR1B,SLC1A2,DTNA,SLC1A3,MGAT4C,ABLIM1
5.246e-03	-5.25	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	48	QKI,FGFR3
5.259e-03	-5.25	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	3	19454	50	NFIA,NFIB,SOX5
5.299e-03	-5.24	heparanase activity	molecular function	GO:0030305	2	1	18094	48	HPSE2
5.299e-03	-5.24	histone H3T6 kinase activity	molecular function	GO:0035403	2	1	18094	48	PRKCA
5.299e-03	-5.24	calcium,diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004698	2	1	18094	48	PRKCA
5.299e-03	-5.24	leukemia inhibitory factor receptor activity	molecular function	GO:0004923	2	1	18094	48	LIFR
5.366e-03	-5.23	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	12	16828	48	HPSE2,FBXL7,PCDH9,FMN2,CDH20,PTPRZ1,PREX2,NTRK2,NEBL,PITPNC1,ATP13A4,ADCY2
5.376e-03	-5.23	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0050653	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	positive regulation of dense core granule biogenesis	biological process	GO:2000707	2	1	18204	49	PRKCA
5.376e-03	-5.23	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	49	QKI
5.376e-03	-5.23	UDP-glucuronate metabolic process	biological process	GO:0046398	2	1	18204	49	CSGALNACT1
5.376e-03	-5.23	fibroblast growth factor receptor apoptotic signaling pathway	biological process	GO:1902178	2	1	18204	49	FGFR3
5.376e-03	-5.23	negative regulation of mesenchymal cell proliferation involved in lung development	biological process	GO:2000791	2	1	18204	49	NFIB
5.376e-03	-5.23	cell differentiation involved in salivary gland development	biological process	GO:0060689	2	1	18204	49	NFIB
5.376e-03	-5.23	regulation of mesenchymal cell proliferation involved in lung development	biological process	GO:2000790	2	1	18204	49	NFIB
5.376e-03	-5.23	myofibroblast contraction	biological process	GO:1990764	2	1	18204	49	QKI
5.377e-03	-5.23	somatodendritic compartment	cellular component	GO:0036477	842	7	19108	49	ATP1A2,ADCY2,NTRK2,SLC1A3,GPM6A,BMPR1B,CTNND2
5.386e-03	-5.22	membrane	cellular component	GO:0016020	9220	33	19108	49	GPM6A,BMPR1B,HPSE2,SFXN5,CSGALNACT1,ATP1A2,FMN2,MGAT4C,NRG3,FGFR3,AQP4,TNIK,PTPRZ1,PRKCA,CTNND2,NTM,PCDH9,NKAIN3,MACF1,CDH20,DPP10,ITPR2,PON2,DTNA,SLC1A3,LIFR,ATP13A4,PARD3B,SLC1A2,LSAMP,PREX2,NTRK2,ADCY2
5.392e-03	-5.22	LIFR_D2	interpro domains	IPR040817	2	1	18521	50	LIFR
5.392e-03	-5.22	LIF-R-like_Ig-like	interpro domains	IPR048497	2	1	18521	50	LIFR
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Par3/HAL_N	interpro domains	IPR021922	2	1	18521	50	PARD3B
5.392e-03	-5.22	MSI_RRM2	interpro domains	IPR034126	2	1	18521	50	MSI2
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Paraoxonase2	interpro domains	IPR008364	2	1	18521	50	PON2
5.392e-03	-5.22	Formin_Cappuccino_subfam	interpro domains	IPR001265	2	1	18521	50	FMN2
5.392e-03	-5.22	Glyco_hydro_79	interpro domains	IPR005199	2	1	18521	50	HPSE2
5.440e-03	-5.21	monoatomic ion transmembrane transport	biological process	GO:0034220	804	7	18204	49	ITPR2,GPM6A,ATP13A4,SFXN5,SLC1A2,SLC1A3,ATP1A2
5.489e-03	-5.21	RNA Polymerase III Transcription	REACTOME pathways	R-HSA-74158	41	2	10285	28	NFIB,NFIA
5.489e-03	-5.21	RNA Polymerase III Abortive And Retractive Initiation	REACTOME pathways	R-HSA-749476	41	2	10285	28	NFIA,NFIB
5.493e-03	-5.20	PK_Tyr_Ser-Thr	pfam domains	PF07714	130	3	17795	49	FGFR3,NTRK2,BMPR1B
5.500e-03	-5.20	Glyco_hydro_79n	pfam domains	PF03662	2	1	17795	49	HPSE2
5.500e-03	-5.20	LIFR_D2	pfam domains	PF17971	2	1	17795	49	LIFR
5.500e-03	-5.20	Par3_HAL_N_term	pfam domains	PF12053	2	1	17795	49	PARD3B
5.500e-03	-5.20	LIF-R_Ig-like	pfam domains	PF21177	2	1	17795	49	LIFR
5.545e-03	-5.19	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	48	SLC1A2,SLC1A3
5.547e-03	-5.19	Ser-Thr/Tyr_kinase_cat_dom	interpro domains	IPR001245	133	3	18521	50	FGFR3,BMPR1B,NTRK2
5.585e-03	-5.19	SATB2 (SATB homeobox 2)	protein interactions	23314	140	3	19454	50	SOX5,NFIB,NFIA
5.612e-03	-5.18	growth factor binding	molecular function	GO:0019838	136	3	18094	48	NTRK2,FGFR3,LIFR
5.664e-03	-5.17	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	39	16828	48	ADCY2,ABLIM1,DTNA,NEBL,ATP1A2,SPARCL1,LSAMP,PON2,CDH20,CSGALNACT1,NPAS3,FMN2,QKI,PCDH9,HPSE2,PRKCA,MGAT4C,SLC1A3,MACF1,NKAIN3,ITPR2,GPM6A,SOX5,NRG3,ATP13A4,AQP4,NTRK2,ZBTB20,PREX2,PTPRZ1,EFEMP1,CTNND2,TNIK,SFXN5,NFIB,FGFR3,FBXL7,NHSL1,SLC1A2
5.681e-03	-5.17	leg	COSMIC cancer mutations	leg	969	8	16828	48	FGFR3,ZBTB20,PTPRZ1,NTM,FMN2,NRG3,ATP13A4,NEBL
5.767e-03	-5.16	sarcolemma	cellular component	GO:0042383	142	3	19108	49	AQP4,ATP1A2,DTNA
5.890e-03	-5.13	response to wounding	biological process	GO:0009611	431	5	18204	49	SLC1A3,NFIB,SLC1A2,MACF1,NFIA
5.935e-03	-5.13	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	4	18094	48	ATP13A4,SLC1A3,ATP1A2,SLC1A2
5.946e-03	-5.12	spleen	COSMIC cancer mutations	spleen	408	5	16828	48	PARD3B,ADCY2,NTM,TNIK,PTPRZ1
5.997e-03	-5.12	FLOT1 (flotillin 1)	protein interactions	10211	453	5	19454	50	ABLIM1,SOX5,DTNA,MACF1,FMN2
6.024e-03	-5.11	Vasopressin regulates renal water homeostasis via Aquaporins	REACTOME pathways	R-HSA-432040	43	2	10285	28	AQP4,ADCY2
6.032e-03	-5.11	intracellular signal transduction	biological process	GO:0035556	1505	10	18204	49	PRKCA,ATP1A2,FMN2,TNIK,MAST4,NRG3,PREX2,FGFR3,ADCY2,ITPR2
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	MACF1,ABLIM1,ZBTB20
6.066e-03	-5.11	signaling	biological process	GO:0023052	4968	22	18204	49	TNIK,NTRK2,PRKCA,PREX2,CTNND2,FGFR3,LIFR,NRG3,MAST4,SLC1A2,EFEMP1,ITPR2,ADCY2,MACF1,SLC1A3,BMPR1B,FMN2,NFIA,DTNA,SPARCL1,PITPNC1,ATP1A2
6.091e-03	-5.10	behavior	biological process	GO:0007610	619	6	18204	49	SLC1A2,ATP1A2,NTRK2,PTPRZ1,PREX2,SLC1A3
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	SLC1A2,DTNA,GPM6A,NTRK2,NFIB,PCDH9
6.108e-03	-5.10	LCK (LCK proto-oncogene, Src family tyrosine kinase)	protein interactions	3932	455	5	19454	50	CTNND2,DTNA,MACF1,FMN2,PRKCA
6.132e-03	-5.09	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	20	16828	48	PCDH9,QKI,FMN2,CSGALNACT1,CTNND2,SLC1A2,MGAT4C,PRKCA,FGFR3,PARD3B,ATP1A2,NEBL,NRG3,ATP13A4,ABLIM1,ITPR2,MACF1,CDH20,PREX2,PON2
6.141e-03	-5.09	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	5	18094	48	ITPR2,SLC1A2,GPM6A,ATP1A2,SLC1A3
6.159e-03	-5.09	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	48	ITPR2,SLC1A2,ATP1A2,SLC1A3,GPM6A,ATP13A4
6.164e-03	-5.09	GSK3A (glycogen synthase kinase 3 alpha)	protein interactions	2931	456	5	19454	50	TNIK,PRKCA,MAST4,NHSL1,MACF1
6.168e-03	-5.09	ATPASE_E1_E2	prosite domains	PS00154	36	2	12186	40	ATP1A2,ATP13A4
6.207e-03	-5.08	uveal_tract	COSMIC cancer mutations	uveal_tract	587	6	16828	48	PCDH9,CTNND2,MACF1,ADCY2,PREX2,FGFR3
6.231e-03	-5.08	CATATPASE	prints domains	PR00119	35	2	5227	18	ATP13A4,ATP1A2
6.272e-03	-5.07	DSCR9 (Down syndrome critical region 9)	protein interactions	257203	146	3	19454	50	MACF1,EFEMP1,SPARCL1
6.281e-03	-5.07	animal organ development	biological process	GO:0048513	2846	15	18204	49	NTRK2,NFIA,CSGALNACT1,BMPR1B,ABLIM1,ATP1A2,SLC1A2,EFEMP1,GPM6A,SOX5,NRG3,NEBL,FGFR3,NFIB,PCDH9
6.324e-03	-5.06	protein tyrosine kinase activity	molecular function	GO:0004713	142	3	18094	48	NTRK2,FGFR3,EFEMP1
6.335e-03	-5.06	neurotransmitter transport	biological process	GO:0006836	140	3	18204	49	ATP1A2,SLC1A3,SLC1A2
6.398e-03	-5.05	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	37	16828	48	PCDH9,NFIA,BMPR1B,CSGALNACT1,FMN2,NPAS3,QKI,MGAT4C,PRKCA,HPSE2,SPARCL1,ABLIM1,NEBL,ATP1A2,DTNA,NTM,LIFR,CDH20,TNIK,MSI2,CTNND2,DPP10,FGFR3,FBXL7,PARD3B,NFIB,NRG3,ATP13A4,PITPNC1,NKAIN3,ITPR2,MACF1,SOX5,GPM6A,PREX2,PTPRZ1,NTRK2
6.467e-03	-5.04	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	39	16828	48	TNIK,SFXN5,MSI2,CTNND2,DPP10,SLC1A2,NHSL1,FGFR3,FBXL7,PARD3B,ATP13A4,NRG3,MACF1,ITPR2,SOX5,GLIS3,PREX2,PTPRZ1,EFEMP1,ZBTB20,NTRK2,PCDH9,BMPR1B,CSGALNACT1,FMN2,NPAS3,QKI,MGAT4C,SLC1A3,PRKCA,HPSE2,ATP1A2,DTNA,NEBL,NTM,ADCY2,LIFR,LSAMP,CDH20
6.472e-03	-5.04	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	37	16828	48	PARD3B,NFIB,FGFR3,FBXL7,CTNND2,DPP10,MSI2,TNIK,NTRK2,PTPRZ1,PREX2,NKAIN3,ITPR2,MACF1,SOX5,GPM6A,NRG3,ATP13A4,PITPNC1,HPSE2,PRKCA,MGAT4C,BMPR1B,CSGALNACT1,NPAS3,QKI,FMN2,NFIA,PCDH9,CDH20,NTM,LIFR,ABLIM1,ATP1A2,DTNA,NEBL,SPARCL1
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	PTPRZ1,GPM6A
6.512e-03	-5.03	ATXN1L (ataxin 1 like)	protein interactions	342371	148	3	19454	50	NFIB,NFIA,SOX5
6.554e-03	-5.03	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	40	SPARCL1
6.554e-03	-5.03	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	40	SPARCL1
6.599e-03	-5.02	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	9	19454	50	MSI2,LSAMP,QKI,MACF1,ITPR2,SOX5,GLIS3,NFIA,NFIB
6.618e-03	-5.02	oligoastrocytoma_Grade_III	COSMIC cancer mutations	oligoastrocytoma_Grade_III	263	4	16828	48	PREX2,SLC1A2,FGFR3,SOX5
6.634e-03	-5.02	KMT2D (lysine methyltransferase 2D)	protein interactions	8085	149	3	19454	50	SOX5,NFIA,NFIB
6.702e-03	-5.01	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	48	HPSE2,MGAT4C,NPAS3,BMPR1B,PCDH9,LSAMP,ADCY2,DTNA,ABLIM1,SPARCL1,FBXL7,FGFR3,NHSL1,SLC1A2,DPP10,CTNND2,MSI2,SFXN5,ZBTB20,EFEMP1,PREX2,GPM6A,ITPR2,NKAIN3,PRKCA,SLC1A3,FMN2,QKI,CSGALNACT1,NFIA,CDH20,LIFR,ATP1A2,NEBL,PARD3B,NFIB,TNIK,NTRK2,PTPRZ1,GLIS3,SOX5,MACF1,ATP13A4,PITPNC1,NRG3,AQP4
6.702e-03	-5.01	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	48	LIFR,NEBL,ATP1A2,CDH20,CSGALNACT1,QKI,FMN2,NFIA,SLC1A3,PRKCA,MACF1,SOX5,AQP4,NRG3,ATP13A4,PITPNC1,NTRK2,GLIS3,PTPRZ1,TNIK,NFIB,PARD3B,ADCY2,SPARCL1,ABLIM1,DTNA,LSAMP,BMPR1B,NPAS3,PCDH9,HPSE2,MGAT4C,NKAIN3,ITPR2,GPM6A,PREX2,EFEMP1,ZBTB20,CTNND2,DPP10,SFXN5,MSI2,FGFR3,FBXL7,SLC1A2,NHSL1
6.755e-03	-5.00	cell communication	biological process	GO:0007154	5010	22	18204	49	MAST4,SLC1A2,EFEMP1,PITPNC1,ATP1A2,DTNA,SPARCL1,LIFR,CTNND2,FGFR3,PREX2,NRG3,BMPR1B,TNIK,FMN2,NFIA,PRKCA,NTRK2,ITPR2,ADCY2,MACF1,SLC1A3
6.757e-03	-5.00	KDM2B (lysine demethylase 2B)	protein interactions	84678	150	3	19454	50	SOX5,NFIA,NFIB
6.812e-03	-4.99	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	49	QKI,PTPRZ1
6.812e-03	-4.99	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	49	PTPRZ1,QKI
6.875e-03	-4.98	Ig_3	pfam domains	PF13927	141	3	17795	49	FGFR3,NTM,LSAMP
6.876e-03	-4.98	PARAOXONASE2	prints domains	PR01787	2	1	5227	18	PON2
6.876e-03	-4.98	FORMIN	prints domains	PR00828	2	1	5227	18	FMN2
7.053e-03	-4.95	abdomen	COSMIC cancer mutations	abdomen	603	6	16828	48	PREX2,FGFR3,FMN2,ITPR2,CTNND2,DPP10
7.064e-03	-4.95	SP7 (Sp7 transcription factor)	protein interactions	121340	297	4	19454	50	QKI,SOX5,NFIA,NFIB
7.110e-03	-4.95	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	13	16828	48	PRKCA,FGFR3,PARD3B,TNIK,NFIA,BMPR1B,PREX2,PTPRZ1,NTRK2,DTNA,ATP1A2,ADCY2,SOX5
7.111e-03	-4.95	mitotic cell cycle phase transition	biological process	GO:0044772	146	3	18204	49	NFIB,NFIA,FBXL7
7.111e-03	-4.95	adult behavior	biological process	GO:0030534	146	3	18204	49	ATP1A2,PREX2,SLC1A2
7.135e-03	-4.94	SOX6 (SRY-box transcription factor 6)	protein interactions	55553	153	3	19454	50	SOX5,NFIA,NFIB
7.170e-03	-4.94	cell junction assembly	biological process	GO:0034329	285	4	18204	49	GPM6A,CDH20,PRKCA,NRG3
7.175e-03	-4.94	PDZ	interpro domains	IPR001478	146	3	18521	50	MAST4,PARD3B,PREX2
7.221e-03	-4.93	eye	COSMIC cancer mutations	eye	606	6	16828	48	PCDH9,CTNND2,MACF1,ADCY2,PREX2,FGFR3
7.272e-03	-4.92	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	48	NRG3,FGFR3,QKI
7.295e-03	-4.92	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma	45	2	16828	48	MGAT4C,MACF1
7.295e-03	-4.92	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	48	QKI,FGFR3
7.295e-03	-4.92	enteropathy_type_T_cell_lymphoma	COSMIC cancer mutations	enteropathy_type_T_cell_lymphoma	45	2	16828	48	MGAT4C,MACF1
7.330e-03	-4.92	ANXA3 (annexin A3)	protein interactions	306	50	2	19454	50	FGFR3,EFEMP1
7.368e-03	-4.91	Signaling pathways regulating pluripotency of stem cells	KEGG pathways	hsa04550	139	3	7161	21	FGFR3,LIFR,BMPR1B
7.368e-03	-4.91	Signaling pathways regulating pluripotency of stem cells	KEGG pathways	ko04550	139	3	7161	21	FGFR3,LIFR,BMPR1B
7.390e-03	-4.91	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	5	16828	48	TNIK,PRKCA,FGFR3,BMPR1B,NTRK2
7.390e-03	-4.91	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	5	16828	48	TNIK,PRKCA,BMPR1B,FGFR3,NTRK2
7.455e-03	-4.90	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	5	12186	40	PRKCA,BMPR1B,NTRK2,TNIK,FGFR3
7.462e-03	-4.90	G alpha (z) signalling events	REACTOME pathways	R-HSA-418597	48	2	10285	28	PRKCA,ADCY2
7.572e-03	-4.88	positive regulation of cell development	biological process	GO:0010720	458	5	18204	49	MACF1,PRKCA,NTRK2,QKI,PTPRZ1
7.587e-03	-4.88	PDZ_sf	interpro domains	IPR036034	149	3	18521	50	PREX2,PARD3B,MAST4
7.612e-03	-4.88	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma	46	2	16828	48	DPP10,ITPR2
7.617e-03	-4.88	Ndc80 (NDC80 kinetochore complex component)	protein interactions	67052	51	2	19454	50	MACF1,NHSL1
7.617e-03	-4.88	LINGO1 (leucine rich repeat and Ig domain containing 1)	protein interactions	84894	51	2	19454	50	PON2,NTM
7.674e-03	-4.87	alphav-beta3 integrin-PKCalpha complex	cellular component	GO:0035866	3	1	19108	49	PRKCA
7.691e-03	-4.87	Atg16l1 (autophagy related 16 like 1)	protein interactions	77040	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Stk35 (serine/threonine kinase 35)	protein interactions	67333	3	1	19454	50	BMPR1B
7.691e-03	-4.87	BCO1 (beta-carotene oxygenase 1)	protein interactions	53630	3	1	19454	50	ABLIM1
7.691e-03	-4.87	Rap2a (RAS related protein 2a)	protein interactions	76108	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Grm5 (glutamate metabotropic receptor 5)	protein interactions	24418	3	1	19454	50	PRKCA
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Usp45 (ubiquitin specific petidase 45)	protein interactions	77593	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Smad6 (SMAD family member 6)	protein interactions	17130	3	1	19454	50	BMPR1B
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.691e-03	-4.87	Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1)	protein interactions	27276	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Fbxw5 (F-box and WD-40 domain protein 5)	protein interactions	30839	3	1	19454	50	BMPR1B
7.691e-03	-4.87	Chn1 (chimerin 1)	protein interactions	108699	3	1	19454	50	BMPR1B
7.938e-03	-4.84	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047237	3	1	18094	48	CSGALNACT1
7.938e-03	-4.84	epidermal growth factor receptor activity	molecular function	GO:0005006	3	1	18094	48	EFEMP1
7.938e-03	-4.84	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular function	GO:0008454	3	1	18094	48	MGAT4C
7.938e-03	-4.84	lactonohydrolase activity	molecular function	GO:0046573	3	1	18094	48	PON2
7.938e-03	-4.84	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	48	ITPR2
7.938e-03	-4.84	acyl-L-homoserine-lactone lactonohydrolase activity	molecular function	GO:0102007	3	1	18094	48	PON2
7.938e-03	-4.84	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	48	SLC1A2
7.938e-03	-4.84	oncostatin-M receptor activity	molecular function	GO:0004924	3	1	18094	48	LIFR
7.987e-03	-4.83	cellular response to organic cyclic compound	biological process	GO:0071407	464	5	18204	49	SLC1A2,SLC1A3,ATP1A2,ITPR2,ADCY2
8.045e-03	-4.82	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	5	16828	48	PRKCA,TNIK,NTRK2,FGFR3,BMPR1B
8.054e-03	-4.82	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	49	NTRK2
8.054e-03	-4.82	formin-nucleated actin cable assembly	biological process	GO:0070649	3	1	18204	49	FMN2
8.054e-03	-4.82	UDP-N-acetylgalactosamine metabolic process	biological process	GO:0019276	3	1	18204	49	CSGALNACT1
8.054e-03	-4.82	regulation of dense core granule biogenesis	biological process	GO:2000705	3	1	18204	49	PRKCA
8.054e-03	-4.82	meiotic chromosome movement towards spindle pole	biological process	GO:0016344	3	1	18204	49	FMN2
8.054e-03	-4.82	cysteine transport	biological process	GO:0042883	3	1	18204	49	SLC1A2
8.054e-03	-4.82	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	49	ATP1A2
8.054e-03	-4.82	formin-nucleated actin cable organization	biological process	GO:0110009	3	1	18204	49	FMN2
8.054e-03	-4.82	cardiac muscle thin filament assembly	biological process	GO:0071691	3	1	18204	49	NEBL
8.054e-03	-4.82	mammary placode formation	biological process	GO:0060596	3	1	18204	49	NRG3
8.054e-03	-4.82	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	49	SLC1A2
8.065e-03	-4.82	SOX5 (SRY-box transcription factor 5)	protein interactions	6660	160	3	19454	50	SOX5,NFIA,NFIB
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.078e-03	-4.82	Myelin_PLP_CS	interpro domains	IPR018237	3	1	18521	50	GPM6A
8.078e-03	-4.82	Myelin_PLP	interpro domains	IPR001614	3	1	18521	50	GPM6A
8.078e-03	-4.82	Arylesterase	interpro domains	IPR002640	3	1	18521	50	PON2
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	Protein_kinase_C_a/b/g	interpro domains	IPR014375	3	1	18521	50	PRKCA
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.122e-03	-4.81	Adrenergic signaling in cardiomyocytes	KEGG pathways	ko04261	144	3	7161	21	PRKCA,ADCY2,ATP1A2
8.122e-03	-4.81	Adrenergic signaling in cardiomyocytes	KEGG pathways	hsa04261	144	3	7161	21	ATP1A2,ADCY2,PRKCA
8.124e-03	-4.81	neuronal cell body	cellular component	GO:0043025	489	5	19108	49	ATP1A2,BMPR1B,GPM6A,SLC1A3,CTNND2
8.172e-03	-4.81	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	49	PTPRZ1,QKI,NTRK2,MACF1
8.178e-03	-4.81	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	hsa04961	47	2	7161	21	PRKCA,ATP1A2
8.178e-03	-4.81	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	ko04961	47	2	7161	21	PRKCA,ATP1A2
8.183e-03	-4.81	Spinal Cord Injury	WikiPathways	WP2431	119	3	5310	19	PTPRZ1,AQP4,PRKCA
8.194e-03	-4.80	small molecule binding	molecular function	GO:0036094	6197	25	18094	48	TNIK,GLIS3,CSGALNACT1,ZBTB20,PON2,ATP13A4,EFEMP1,PCDH9,ATP1A2,FGFR3,MACF1,MAST4,ITPR2,ADCY2,ETNPPL,SPARCL1,BMPR1B,SLC1A2,DTNA,NTRK2,PITPNC1,PRKCA,MGAT4C,SLC1A3,ABLIM1
8.238e-03	-4.80	Arylesterase	pfam domains	PF01731	3	1	17795	49	PON2
8.238e-03	-4.80	Myelin_PLP	pfam domains	PF01275	3	1	17795	49	GPM6A
8.238e-03	-4.80	LRRCT_2	pfam domains	PF16920	3	1	17795	49	NTRK2
8.238e-03	-4.80	SR_plectin_7	pfam domains	PF21097	3	1	17795	49	MACF1
8.244e-03	-4.80	transmembrane transporter activity	molecular function	GO:0022857	1110	8	18094	48	SLC1A3,ATP13A4,SLC1A2,AQP4,ATP1A2,GPM6A,SFXN5,ITPR2
8.267e-03	-4.80	carboxylic acid transport	biological process	GO:0046942	297	4	18204	49	SFXN5,SLC1A2,NTRK2,SLC1A3
8.363e-03	-4.78	organic acid transport	biological process	GO:0015849	298	4	18204	49	SFXN5,NTRK2,SLC1A3,SLC1A2
8.392e-03	-4.78	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	28	SLC1A3,SLC1A2
8.392e-03	-4.78	Signaling by ERBB2	REACTOME pathways	R-HSA-1227986	51	2	10285	28	PRKCA,NRG3
8.461e-03	-4.77	anion binding	molecular function	GO:0043168	2412	13	18094	48	ADCY2,SLC1A3,ETNPPL,ATP1A2,FGFR3,ITPR2,MAST4,NTRK2,ATP13A4,PITPNC1,PRKCA,BMPR1B,TNIK
8.476e-03	-4.77	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	3	18094	48	ATP1A2,SLC1A3,SLC1A2
8.507e-03	-4.77	TAFA4 (TAFA chemokine like family member 4)	protein interactions	151647	54	2	19454	50	LIFR,ITPR2
8.533e-03	-4.76	skin-trunk-lentigo	COSMIC cancer mutations	skin-trunk-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-face-lentigo	COSMIC cancer mutations	skin-face-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	lentigo	COSMIC cancer mutations	lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-lentigo	COSMIC cancer mutations	skin-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	urinary_tract-bladder-papilloma	COSMIC cancer mutations	urinary_tract-bladder-papilloma	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-leg-lentigo	COSMIC cancer mutations	skin-leg-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-hand-lentigo	COSMIC cancer mutations	skin-hand-lentigo	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-leg-other-seborrhoeic_keratosis	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-trunk-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-trunk-other-seborrhoeic_keratosis	3	1	16828	48	FGFR3
8.533e-03	-4.76	skin-forearm-lentigo	COSMIC cancer mutations	skin-forearm-lentigo	3	1	16828	48	FGFR3
8.602e-03	-4.76	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	6	10285	28	SLC1A3,AQP4,ATP13A4,ADCY2,ATP1A2,SLC1A2
8.712e-03	-4.74	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular function	GO:0019829	53	2	18094	48	ATP13A4,ATP1A2
8.713e-03	-4.74	Aquaporin-mediated transport	REACTOME pathways	R-HSA-445717	52	2	10285	28	ADCY2,AQP4
8.860e-03	-4.73	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	13	16828	48	EFEMP1,PTPRZ1,SLC1A2,NHSL1,ZBTB20,HPSE2,NTRK2,PCDH9,ATP1A2,NRG3,FMN2,SOX5,CTNND2
8.917e-03	-4.72	SCLT1 (sodium channel and clathrin linker 1)	protein interactions	132320	166	3	19454	50	NEBL,ATP1A2,ABLIM1
8.928e-03	-4.72	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	6	16828	48	PTPRZ1,PREX2,FMN2,NTM,NFIA,NEBL
8.962e-03	-4.71	neutral amino acid transport	biological process	GO:0015804	53	2	18204	49	SLC1A2,SLC1A3
8.979e-03	-4.71	cell cycle phase transition	biological process	GO:0044770	159	3	18204	49	NFIB,NFIA,FBXL7
9.159e-03	-4.69	-	gene3d domains	2.30.42.10	149	3	14470	42	PREX2,MAST4,PARD3B
9.272e-03	-4.68	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	4	16828	48	PARD3B,FGFR3,NRG3,SLC1A2
9.272e-03	-4.68	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	4	16828	48	FGFR3,PARD3B,SLC1A2,NRG3
9.280e-03	-4.68	transferase activity, transferring phosphorus-containing groups	molecular function	GO:0016772	903	7	18094	48	TNIK,FGFR3,BMPR1B,MAST4,NTRK2,EFEMP1,PRKCA
9.293e-03	-4.68	haematopoietic_and_lymphoid_tissue-tonsil-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-tonsil-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	51	2	16828	48	ITPR2,DPP10
9.393e-03	-4.67	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	5	16828	48	TNIK,PRKCA,BMPR1B,FGFR3,NTRK2
9.420e-03	-4.66	Oxytocin signaling pathway	KEGG pathways	ko04921	152	3	7161	21	ITPR2,PRKCA,ADCY2
9.420e-03	-4.66	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	3	7161	21	ITPR2,ADCY2,PRKCA
9.475e-03	-4.66	Ser/Thr_kinase_AS	interpro domains	IPR008271	308	4	18521	50	MAST4,BMPR1B,PRKCA,TNIK
9.482e-03	-4.66	FOXA1 transcription factor network	Pathway Interaction DB	hnf3apathway	43	2	2226	8	NFIB,NFIA
9.561e-03	-4.65	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	5	16828	48	BMPR1B,FGFR3,NTRK2,TNIK,PRKCA
9.625e-03	-4.64	response to cocaine	biological process	GO:0042220	55	2	18204	49	SLC1A2,SLC1A3
9.682e-03	-4.64	AGC-kinase_C	interpro domains	IPR000961	55	2	18521	50	PRKCA,MAST4
9.733e-03	-4.63	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	15	16828	48	PCDH9,TNIK,FMN2,DPP10,CTNND2,NHSL1,FGFR3,SPARCL1,NRG3,PITPNC1,MACF1,NKAIN3,ITPR2,PTPRZ1,PREX2
9.733e-03	-4.63	gallbladder	COSMIC cancer mutations	gallbladder	2821	15	16828	48	PREX2,PTPRZ1,MACF1,ITPR2,NKAIN3,SPARCL1,PITPNC1,NRG3,FGFR3,NHSL1,FMN2,DPP10,CTNND2,PCDH9,TNIK
9.751e-03	-4.63	dendritic spine	cellular component	GO:0043197	172	3	19108	49	NTRK2,ATP1A2,GPM6A
9.763e-03	-4.63	SNAP25 (synaptosome associated protein 25)	protein interactions	6616	58	2	19454	50	GPM6A,PRKCA
9.763e-03	-4.63	CILK1 (ciliogenesis associated kinase 1)	protein interactions	22858	58	2	19454	50	MAST4,MSI2
9.816e-03	-4.62	MYELIN_PLP_2	prosite domains	PS01004	3	1	12186	40	GPM6A
9.816e-03	-4.62	MYELIN_PLP_1	prosite domains	PS00575	3	1	12186	40	GPM6A
9.840e-03	-4.62	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	48	MSI2,TNIK,CTNND2,BMPR1B,NPAS3,QKI,PRKCA,SLC1A3,NFIB,FGFR3,FBXL7,ABLIM1,PITPNC1,ATP13A4,SPARCL1,ITPR2,SOX5,ADCY2,LIFR,LSAMP,PTPRZ1,PREX2,NTRK2
9.840e-03	-4.62	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	48	ADCY2,LIFR,ITPR2,SOX5,SPARCL1,ABLIM1,PITPNC1,ATP13A4,NTRK2,LSAMP,PREX2,PTPRZ1,BMPR1B,QKI,NPAS3,CTNND2,TNIK,MSI2,FGFR3,FBXL7,NFIB,SLC1A3,PRKCA
9.871e-03	-4.62	cell-cell junction	cellular component	GO:0005911	513	5	19108	49	CDH20,CTNND2,PARD3B,ATP1A2,PCDH9
9.883e-03	-4.62	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	6	16828	48	TNIK,BMPR1B,PREX2,PRKCA,FGFR3,NTRK2
9.929e-03	-4.61	import across plasma membrane	biological process	GO:0098739	165	3	18204	49	SLC1A2,SLC1A3,ATP1A2
1.005e-02	-4.60	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	2	10285	28	ITPR2,ATP1A2
1.006e-02	-4.60	neuron spine	cellular component	GO:0044309	174	3	19108	49	ATP1A2,GPM6A,NTRK2
1.008e-02	-4.60	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	5	16828	48	TNIK,PRKCA,FGFR3,BMPR1B,NTRK2
1.009e-02	-4.60	HTATIP2 (HIV-1 Tat interactive protein 2)	protein interactions	10553	59	2	19454	50	PITPNC1,PRKCA
1.013e-02	-4.59	DUSP14 (dual specificity phosphatase 14)	protein interactions	11072	174	3	19454	50	QKI,SPARCL1,CSGALNACT1
1.023e-02	-4.58	positive regulation of cell differentiation	biological process	GO:0045597	906	7	18204	49	NTRK2,SOX5,PRKCA,MACF1,PTPRZ1,BMPR1B,QKI
1.024e-02	-4.58	Pick1 (protein interacting with PRKCA 1)	protein interactions	84591	4	1	19454	50	PRKCA
1.024e-02	-4.58	Arhgef6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	73341	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Cdk14 (cyclin dependent kinase 14)	protein interactions	18647	4	1	19454	50	BMPR1B
1.024e-02	-4.58	AVPR1A (arginine vasopressin receptor 1A)	protein interactions	552	4	1	19454	50	PRKCA
1.024e-02	-4.58	Nkiras1 (NFKB inhibitor interacting Ras-like protein 1)	protein interactions	69721	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Srgap1 (SLIT-ROBO Rho GTPase activating protein 1)	protein interactions	117600	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)	protein interactions	67877	4	1	19454	50	BMPR1B
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	Rhebl1 (Ras homolog enriched in brain like 1)	protein interactions	69159	4	1	19454	50	BMPR1B
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C)	protein interactions	67444	4	1	19454	50	BMPR1B
1.029e-02	-4.58	LHX3 (LIM homeobox 3)	protein interactions	8022	175	3	19454	50	SOX5,NFIA,NFIB
1.030e-02	-4.58	NTKRECEPTOR	prints domains	PR01939	3	1	5227	18	NTRK2
1.030e-02	-4.58	PARAOXONASE	prints domains	PR01785	3	1	5227	18	PON2
1.030e-02	-4.58	MYELINPLP	prints domains	PR00214	3	1	5227	18	GPM6A
1.030e-02	-4.58	INSP3RECEPTR	prints domains	PR00779	3	1	5227	18	ITPR2
1.030e-02	-4.58	cellular response to growth factor stimulus	biological process	GO:0071363	494	5	18204	49	BMPR1B,SOX5,NTRK2,NFIA,FGFR3
1.031e-02	-4.57	visual behavior	biological process	GO:0007632	57	2	18204	49	ATP1A2,SLC1A2
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	FGFR3,DTNA
1.057e-02	-4.55	ciliary neurotrophic factor receptor activity	molecular function	GO:0004897	4	1	18094	48	LIFR
1.057e-02	-4.55	citrate transmembrane transporter activity	molecular function	GO:0015137	4	1	18094	48	SFXN5
1.057e-02	-4.55	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	48	NTRK2
1.057e-02	-4.55	carbon-oxygen lyase activity, acting on phosphates	molecular function	GO:0016838	4	1	18094	48	ETNPPL
1.057e-02	-4.55	tricarboxylic acid transmembrane transporter activity	molecular function	GO:0015142	4	1	18094	48	SFXN5
1.059e-02	-4.55	biliary_tract	COSMIC cancer mutations	biliary_tract	15309	48	16828	48	FBXL7,FGFR3,SLC1A2,NHSL1,DPP10,CTNND2,SFXN5,MSI2,EFEMP1,PREX2,ZBTB20,GPM6A,ITPR2,NKAIN3,HPSE2,MGAT4C,NPAS3,BMPR1B,PCDH9,LSAMP,ADCY2,SPARCL1,DTNA,ABLIM1,PARD3B,NFIB,TNIK,NTRK2,PTPRZ1,GLIS3,SOX5,MACF1,AQP4,PITPNC1,ATP13A4,NRG3,SLC1A3,PRKCA,FMN2,QKI,CSGALNACT1,NFIA,CDH20,PON2,LIFR,NTM,ATP1A2,NEBL
1.061e-02	-4.55	GATA3 (GATA binding protein 3)	protein interactions	2625	177	3	19454	50	QKI,NFIB,NFIA
1.072e-02	-4.54	desmosome assembly	biological process	GO:0002159	4	1	18204	49	PRKCA
1.072e-02	-4.54	trigeminal sensory nucleus development	biological process	GO:0021730	4	1	18204	49	NFIB
1.072e-02	-4.54	ovarian cumulus expansion	biological process	GO:0001550	4	1	18204	49	BMPR1B
1.072e-02	-4.54	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	49	NTRK2
1.072e-02	-4.54	oncostatin-M-mediated signaling pathway	biological process	GO:0038165	4	1	18204	49	LIFR
1.072e-02	-4.54	principal sensory nucleus of trigeminal nerve development	biological process	GO:0021740	4	1	18204	49	NFIB
1.072e-02	-4.54	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	49	SOX5
1.072e-02	-4.54	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	49	ATP1A2
1.072e-02	-4.54	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	49	ATP1A2
1.072e-02	-4.54	regulation of angiotensin-activated signaling pathway	biological process	GO:0110061	4	1	18204	49	PRKCA
1.072e-02	-4.54	leukemia inhibitory factor signaling pathway	biological process	GO:0048861	4	1	18204	49	LIFR
1.072e-02	-4.54	club cell differentiation	biological process	GO:0060486	4	1	18204	49	NFIB
1.072e-02	-4.54	response to glycoside	biological process	GO:1903416	4	1	18204	49	ATP1A2
1.072e-02	-4.54	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	49	NTRK2
1.075e-02	-4.53	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	48	FGFR3,QKI
1.075e-02	-4.53	Ion transport by P-type ATPases	REACTOME pathways	R-HSA-936837	58	2	10285	28	ATP13A4,ATP1A2
1.076e-02	-4.53	P5A-ATPase_N	interpro domains	IPR047819	4	1	18521	50	ATP13A4
1.076e-02	-4.53	Nebulin_repeat	interpro domains	IPR000900	4	1	18521	50	NEBL
1.076e-02	-4.53	AbLIM_anchor	interpro domains	IPR032402	4	1	18521	50	ABLIM1
1.076e-02	-4.53	P5B-type_ATPase	interpro domains	IPR047821	4	1	18521	50	ATP13A4
1.076e-02	-4.53	MAST_pre-PK_dom	interpro domains	IPR015022	4	1	18521	50	MAST4
1.076e-02	-4.53	Desmoplakin_Spectrin-like	interpro domains	IPR041573	4	1	18521	50	MACF1
1.076e-02	-4.53	Na/K-Atpase_Interacting	interpro domains	IPR008516	4	1	18521	50	NKAIN3
1.076e-02	-4.53	Glyco_transf_54	interpro domains	IPR006759	4	1	18521	50	MGAT4C
1.076e-02	-4.53	PCN-like_spectrin-like_rpt	interpro domains	IPR049538	4	1	18521	50	MACF1
1.076e-02	-4.53	MAST_pre-PK_dom_sf	interpro domains	IPR023142	4	1	18521	50	MAST4
1.076e-02	-4.53	NHS-like	interpro domains	IPR024845	4	1	18521	50	NHSL1
1.076e-02	-4.53	FGF_rcpt_fam	interpro domains	IPR016248	4	1	18521	50	FGFR3
1.076e-02	-4.53	MAST	interpro domains	IPR037711	4	1	18521	50	MAST4
1.076e-02	-4.53	PRKG1 (protein kinase cGMP-dependent 1)	protein interactions	5592	61	2	19454	50	PRKCA,TNIK
1.094e-02	-4.52	germ_cell_tumour	COSMIC cancer mutations	germ_cell_tumour	867	7	16828	48	PRKCA,PREX2,TNIK,NTRK2,MACF1,FGFR3,BMPR1B
1.097e-02	-4.51	Spectrin_2	pfam domains	PF18373	4	1	17795	49	MACF1
1.097e-02	-4.51	Spectrin_3	pfam domains	PF21019	4	1	17795	49	MACF1
1.097e-02	-4.51	Nebulin	pfam domains	PF00880	4	1	17795	49	NEBL
1.097e-02	-4.51	NKAIN	pfam domains	PF05640	4	1	17795	49	NKAIN3
1.097e-02	-4.51	NHS	pfam domains	PF15273	4	1	17795	49	NHSL1
1.097e-02	-4.51	P5-ATPase	pfam domains	PF12409	4	1	17795	49	ATP13A4
1.097e-02	-4.51	AbLIM_anchor	pfam domains	PF16182	4	1	17795	49	ABLIM1
1.097e-02	-4.51	Glyco_transf_54	pfam domains	PF04666	4	1	17795	49	MGAT4C
1.097e-02	-4.51	Spectrin_4	pfam domains	PF21020	4	1	17795	49	MACF1
1.097e-02	-4.51	DUF1908	pfam domains	PF08926	4	1	17795	49	MAST4
1.106e-02	-4.50	chondroitin biosynthesis	BIOCYC pathways	META_PWY-6566	5	1	902	2	CSGALNACT1
1.107e-02	-4.50	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	6	18094	48	SLC1A3,SLC1A2,AQP4,ATP1A2,GPM6A,ITPR2
1.107e-02	-4.50	PLP	smart domains	SM00002	3	1	9717	36	GPM6A
1.113e-02	-4.50	functioning	COSMIC cancer mutations	functioning	1803	11	16828	48	NRG3,SOX5,PTPRZ1,EFEMP1,ZBTB20,NTRK2,PCDH9,FMN2,SLC1A2,NHSL1,HPSE2
1.113e-02	-4.50	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	11	16828	48	NHSL1,ZBTB20,SLC1A2,PTPRZ1,EFEMP1,NTRK2,HPSE2,NRG3,PCDH9,SOX5,FMN2
1.115e-02	-4.50	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	8	18204	49	CTNND2,PREX2,NFIB,PTPRZ1,ABLIM1,BMPR1B,GPM6A,TNIK
1.121e-02	-4.49	YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)	protein interactions	7529	965	7	19454	50	ABLIM1,PITPNC1,FGFR3,MACF1,NHSL1,MAST4,PARD3B
1.134e-02	-4.48	IGc2	smart domains	SM00408	239	4	9717	36	NTRK2,FGFR3,LSAMP,NTM
1.136e-02	-4.48	skin-face-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-face-malignant_melanoma-superficial_spreading	4	1	16828	48	PREX2
1.136e-02	-4.48	skin-lower_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-nodular	4	1	16828	48	PREX2
1.136e-02	-4.48	skin-benign_melanocytic_nevus-junctional	COSMIC cancer mutations	skin-benign_melanocytic_nevus-junctional	4	1	16828	48	FGFR3
1.136e-02	-4.48	inverted	COSMIC cancer mutations	inverted	4	1	16828	48	FGFR3
1.136e-02	-4.48	urinary_tract-bladder-other-normal	COSMIC cancer mutations	urinary_tract-bladder-other-normal	4	1	16828	48	FGFR3
1.136e-02	-4.48	urinary_tract-bladder-papilloma-inverted	COSMIC cancer mutations	urinary_tract-bladder-papilloma-inverted	4	1	16828	48	FGFR3
1.137e-02	-4.48	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	49	BMPR1B,CSGALNACT1
1.137e-02	-4.48	transmission of nerve impulse	biological process	GO:0019226	60	2	18204	49	NTRK2,ATP1A2
1.139e-02	-4.48	PDZ	prosite domains	PS50106	143	3	12186	40	MAST4,PARD3B,PREX2
1.139e-02	-4.47	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	3	7161	21	ADCY2,ATP1A2,ITPR2
1.139e-02	-4.47	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	3	7161	21	ADCY2,ITPR2,ATP1A2
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	NAXD (NAD(P)HX dehydratase)	protein interactions	55739	63	2	19454	50	NEBL,PON2
1.145e-02	-4.47	YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma)	protein interactions	7532	1211	8	19454	50	PARD3B,PITPNC1,ABLIM1,PRKCA,FMN2,MAST4,NHSL1,MACF1
1.148e-02	-4.47	Signaling by BRAF and RAF fusions	REACTOME pathways	R-HSA-6802952	60	2	10285	28	MACF1,QKI
1.153e-02	-4.46	response to endogenous stimulus	biological process	GO:0009719	1402	9	18204	49	ITPR2,FGFR3,SLC1A3,SOX5,BMPR1B,SLC1A2,NFIA,ATP1A2,NTRK2
1.156e-02	-4.46	MAST3 pre-PK domain-like	gene3d domains	1.20.1480.20	4	1	14470	42	MAST4
1.156e-02	-4.46	-	gene3d domains	1.20.58.1060	4	1	14470	42	MACF1
1.159e-02	-4.46	VEGFA-VEGFR2 Pathway	REACTOME pathways	R-HSA-4420097	330	4	10285	28	PRKCA,ITPR2,FGFR3,NRG3
1.163e-02	-4.45	back	COSMIC cancer mutations	back	310	4	16828	48	FGFR3,TNIK,PREX2,ATP1A2
1.165e-02	-4.45	Activation of PKC Through G Protein-Coupled Receptor	SMPDB pathways	SMP0000749	4	1	1369	4	PRKCA
1.179e-02	-4.44	LIPG (lipase G, endothelial type)	protein interactions	9388	64	2	19454	50	ETNPPL,FGFR3
1.179e-02	-4.44	VSX1 (visual system homeobox 1)	protein interactions	30813	64	2	19454	50	NFIA,NFIB
1.179e-02	-4.44	EVA1C (eva-1 homolog C)	protein interactions	59271	64	2	19454	50	BMPR1B,PCDH9
1.182e-02	-4.44	central nervous system neuron differentiation	biological process	GO:0021953	176	3	18204	49	BMPR1B,NTRK2,NFIB
1.185e-02	-4.44	Ca2+ pathway	REACTOME pathways	R-HSA-4086398	61	2	10285	28	PRKCA,ITPR2
1.188e-02	-4.43	arm	COSMIC cancer mutations	arm	1331	9	16828	48	FGFR3,PARD3B,PRKCA,ZBTB20,NTM,NPAS3,MACF1,DPP10,ATP1A2
1.202e-02	-4.42	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	39	16828	48	NTRK2,ZBTB20,GLIS3,PTPRZ1,EFEMP1,PREX2,ITPR2,MACF1,SOX5,NRG3,ATP13A4,PARD3B,FGFR3,FBXL7,NHSL1,SLC1A2,CTNND2,DPP10,MSI2,TNIK,SFXN5,LSAMP,CDH20,ADCY2,NTM,LIFR,DTNA,ATP1A2,NEBL,HPSE2,PRKCA,MGAT4C,SLC1A3,CSGALNACT1,BMPR1B,FMN2,QKI,NPAS3,PCDH9
1.202e-02	-4.42	PTPN11 (protein tyrosine phosphatase non-receptor type 11)	protein interactions	5781	347	4	19454	50	FGFR3,PRKCA,NTRK2,LIFR
1.205e-02	-4.42	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	48	16828	48	PREX2,EFEMP1,ZBTB20,GPM6A,NKAIN3,ITPR2,SLC1A2,NHSL1,FBXL7,FGFR3,SFXN5,MSI2,DPP10,CTNND2,LSAMP,SPARCL1,DTNA,ABLIM1,ADCY2,MGAT4C,HPSE2,PCDH9,NPAS3,BMPR1B,PTPRZ1,GLIS3,NTRK2,AQP4,NRG3,ATP13A4,PITPNC1,SOX5,MACF1,NFIB,PARD3B,TNIK,CDH20,PON2,NEBL,ATP1A2,LIFR,NTM,SLC1A3,PRKCA,NFIA,FMN2,QKI,CSGALNACT1
1.212e-02	-4.41	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	12	16828	48	FGFR3,PRKCA,BMPR1B,TNIK,NFIA,NTRK2,PREX2,PTPRZ1,ADCY2,SOX5,ATP1A2,DTNA
1.239e-02	-4.39	adherens junction	cellular component	GO:0005912	188	3	19108	49	CDH20,CTNND2,PARD3B
1.247e-02	-4.38	head_neck	COSMIC cancer mutations	head_neck	15361	48	16828	48	ATP1A2,NEBL,NTM,LIFR,PON2,CDH20,NFIA,CSGALNACT1,FMN2,QKI,SLC1A3,PRKCA,AQP4,PITPNC1,NRG3,ATP13A4,MACF1,SOX5,GLIS3,PTPRZ1,NTRK2,TNIK,NFIB,PARD3B,SPARCL1,ABLIM1,DTNA,ADCY2,LSAMP,PCDH9,BMPR1B,NPAS3,MGAT4C,HPSE2,NKAIN3,ITPR2,GPM6A,EFEMP1,PREX2,ZBTB20,SFXN5,MSI2,CTNND2,DPP10,SLC1A2,NHSL1,FGFR3,FBXL7
1.248e-02	-4.38	HNF1B (HNF1 homeobox B)	protein interactions	6928	188	3	19454	50	NFIA,NFIB,SOX5
1.250e-02	-4.38	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	2	19454	50	NFIB,NFIA
1.258e-02	-4.38	Signaling by VEGF	REACTOME pathways	R-HSA-194138	338	4	10285	28	NRG3,ITPR2,FGFR3,PRKCA
1.258e-02	-4.38	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	7	16828	48	ITPR2,FGFR3,NPAS3,ABLIM1,ATP1A2,PTPRZ1,SPARCL1
1.262e-02	-4.37	Ig-like_fold	interpro domains	IPR013783	721	6	18521	50	PTPRZ1,FGFR3,LIFR,NTRK2,LSAMP,NTM
1.265e-02	-4.37	brain development	biological process	GO:0007420	724	6	18204	49	NFIB,SLC1A2,NTRK2,NRG3,ATP1A2,PCDH9
1.277e-02	-4.36	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	10	18204	49	TNIK,MAST4,BMPR1B,ATP1A2,PRKCA,NTRK2,EFEMP1,ADCY2,PTPRZ1,FGFR3
1.278e-02	-4.36	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	43	16828	48	MGAT4C,HPSE2,PCDH9,BMPR1B,LSAMP,SPARCL1,ABLIM1,ADCY2,SLC1A2,NHSL1,FGFR3,FBXL7,SFXN5,MSI2,CTNND2,DPP10,PREX2,EFEMP1,ZBTB20,ITPR2,NKAIN3,GPM6A,SLC1A3,PRKCA,CSGALNACT1,FMN2,QKI,PON2,CDH20,ATP1A2,NEBL,NTM,LIFR,NFIB,PARD3B,TNIK,GLIS3,NTRK2,AQP4,ATP13A4,NRG3,MACF1,SOX5
1.279e-02	-4.36	Rab6b (RAB6B, member RAS oncogene family)	protein interactions	270192	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Cdk4 (cyclin dependent kinase 4)	protein interactions	12567	5	1	19454	50	BMPR1B
1.279e-02	-4.36	GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2)	protein interactions	2570	5	1	19454	50	PRKCA
1.279e-02	-4.36	CFHR3 (complement factor H related 3)	protein interactions	10878	5	1	19454	50	PRKCA
1.279e-02	-4.36	Rras2 (related RAS viral (r-ras) oncogene 2)	protein interactions	66922	5	1	19454	50	BMPR1B
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	Rhoj (ras homolog family member J)	protein interactions	80837	5	1	19454	50	BMPR1B
1.279e-02	-4.36	DLX3 (distal-less homeobox 3)	protein interactions	1747	5	1	19454	50	PRKCA
1.279e-02	-4.36	Rab38 (RAB38, member RAS oncogene family)	protein interactions	72433	5	1	19454	50	BMPR1B
1.279e-02	-4.36	SUI2 (translation initiation factor eIF2 subunit alpha)	protein interactions	853463	5	1	19454	50	PRKCA
1.279e-02	-4.36	DPP10 (dipeptidyl peptidase like 10)	protein interactions	57628	5	1	19454	50	DPP10
1.279e-02	-4.36	Rhobtb1 (Rho-related BTB domain containing 1)	protein interactions	69288	5	1	19454	50	BMPR1B
1.287e-02	-4.35	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	49	PREX2,CTNND2
1.292e-02	-4.35	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	8	16828	48	FMN2,QKI,ADCY2,SOX5,NRG3,ATP13A4,CDH20,SLC1A2
1.307e-02	-4.34	NEBULIN	prosite domains	PS51216	4	1	12186	40	NEBL
1.309e-02	-4.34	Long-term depression	KEGG pathways	ko04730	60	2	7161	21	PRKCA,ITPR2
1.309e-02	-4.34	Long-term depression	KEGG pathways	hsa04730	60	2	7161	21	PRKCA,ITPR2
1.314e-02	-4.33	response to growth factor	biological process	GO:0070848	525	5	18204	49	FGFR3,NFIA,SOX5,NTRK2,BMPR1B
1.317e-02	-4.33	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	3	18094	48	SFXN5,SLC1A2,SLC1A3
1.320e-02	-4.33	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	48	NTRK2
1.320e-02	-4.33	fibroblast growth factor receptor activity	molecular function	GO:0005007	5	1	18094	48	FGFR3
1.320e-02	-4.33	transforming growth factor beta receptor activity, type I	molecular function	GO:0005025	5	1	18094	48	BMPR1B
1.323e-02	-4.33	kidney	COSMIC cancer mutations	kidney	15380	48	16828	48	MGAT4C,HPSE2,PCDH9,BMPR1B,NPAS3,LSAMP,SPARCL1,ABLIM1,DTNA,ADCY2,SLC1A2,NHSL1,FGFR3,FBXL7,SFXN5,MSI2,CTNND2,DPP10,EFEMP1,PREX2,ZBTB20,NKAIN3,ITPR2,GPM6A,SLC1A3,PRKCA,NFIA,CSGALNACT1,FMN2,QKI,PON2,CDH20,NEBL,ATP1A2,NTM,LIFR,PARD3B,NFIB,TNIK,GLIS3,PTPRZ1,NTRK2,AQP4,NRG3,PITPNC1,ATP13A4,MACF1,SOX5
1.327e-02	-4.32	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	48	SLC1A2,SLC1A3
1.328e-02	-4.32	signal transduction	biological process	GO:0007165	4637	20	18204	49	PITPNC1,EFEMP1,ATP1A2,MAST4,PREX2,CTNND2,FGFR3,LIFR,SPARCL1,NRG3,DTNA,NFIA,NTRK2,PRKCA,BMPR1B,FMN2,TNIK,MACF1,ITPR2,ADCY2
1.328e-02	-4.32	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	10	18204	49	BMPR1B,ZBTB20,QKI,NTRK2,ATP1A2,PRKCA,PTPRZ1,SFXN5,MACF1,SOX5
1.331e-02	-4.32	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	8	16828	48	MGAT4C,PRKCA,FGFR3,NFIB,NTRK2,TNIK,LIFR,CTNND2
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.332e-02	-4.32	human chr8q13.2	chromosome location	human chr8q13.2	7	1	26134	50	PREX2
1.336e-02	-4.32	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	4	16828	48	PTPRZ1,PARD3B,NTM,ADCY2
1.336e-02	-4.32	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	3	18094	48	SFXN5,SLC1A2,SLC1A3
1.337e-02	-4.31	Constitutive Signaling by Aberrant PI3K in Cancer	REACTOME pathways	R-HSA-2219530	65	2	10285	28	FGFR3,NRG3
1.339e-02	-4.31	tube lumen cavitation	biological process	GO:0060605	5	1	18204	49	NFIB
1.339e-02	-4.31	polar body extrusion after meiotic divisions	biological process	GO:0040038	5	1	18204	49	FMN2
1.339e-02	-4.31	ciliary neurotrophic factor-mediated signaling pathway	biological process	GO:0070120	5	1	18204	49	LIFR
1.339e-02	-4.31	citrate transport	biological process	GO:0015746	5	1	18204	49	SFXN5
1.339e-02	-4.31	salivary gland cavitation	biological process	GO:0060662	5	1	18204	49	NFIB
1.339e-02	-4.31	amygdala development	biological process	GO:0021764	5	1	18204	49	ATP1A2
1.339e-02	-4.31	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	49	NTRK2
1.339e-02	-4.31	negative regulation of chondrocyte proliferation	biological process	GO:1902731	5	1	18204	49	BMPR1B
1.339e-02	-4.31	tricarboxylic acid transport	biological process	GO:0006842	5	1	18204	49	SFXN5
1.343e-02	-4.31	PI_transfer	interpro domains	IPR001666	5	1	18521	50	PITPNC1
1.343e-02	-4.31	P-type_TPase_V	interpro domains	IPR006544	5	1	18521	50	ATP13A4
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	Mtc	interpro domains	IPR004686	5	1	18521	50	SFXN5
1.343e-02	-4.31	Aminotrans_3	interpro domains	IPR005814	5	1	18521	50	ETNPPL
1.343e-02	-4.31	Aminotrans_3_PPA_site	interpro domains	IPR049704	5	1	18521	50	ETNPPL
1.345e-02	-4.31	scalp	COSMIC cancer mutations	scalp	2110	12	16828	48	FGFR3,FMN2,NFIA,PTPRZ1,PREX2,LSAMP,SOX5,MACF1,NTM,ATP1A2,NEBL,ATP13A4
1.347e-02	-4.31	extraskeletal	COSMIC cancer mutations	extraskeletal	903	7	16828	48	NPAS3,ITPR2,SPARCL1,ATP1A2,ABLIM1,FGFR3,PTPRZ1
1.354e-02	-4.30	Disinhibition of SNARE formation	REACTOME pathways	R-HSA-114516	5	1	10285	28	PRKCA
1.354e-02	-4.30	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	28	NTRK2
1.358e-02	-4.30	small_intestine-carcinoid-endocrine_tumour	COSMIC cancer mutations	small_intestine-carcinoid-endocrine_tumour	175	3	16828	48	CSGALNACT1,MACF1,TNIK
1.359e-02	-4.30	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	46	16828	48	GPM6A,NKAIN3,ITPR2,ZBTB20,EFEMP1,PREX2,SFXN5,DPP10,CTNND2,NHSL1,SLC1A2,FBXL7,FGFR3,DTNA,ABLIM1,SPARCL1,ADCY2,LSAMP,PCDH9,NPAS3,BMPR1B,MGAT4C,HPSE2,ATP13A4,NRG3,PITPNC1,AQP4,SOX5,MACF1,PTPRZ1,GLIS3,NTRK2,TNIK,PARD3B,NEBL,ATP1A2,LIFR,NTM,CDH20,PON2,NFIA,FMN2,QKI,CSGALNACT1,PRKCA,SLC1A3
1.359e-02	-4.30	Axon guidance	KEGG pathways	hsa04360	174	3	7161	21	ABLIM1,BMPR1B,PRKCA
1.359e-02	-4.30	Axon guidance	KEGG pathways	ko04360	174	3	7161	21	PRKCA,ABLIM1,BMPR1B
1.361e-02	-4.30	cellular component organization	biological process	GO:0016043	5636	23	18204	49	ABLIM1,SLC1A2,CDH20,MAST4,NRG3,NEBL,AQP4,CTNND2,PREX2,NFIB,PTPRZ1,PRKCA,HPSE2,TNIK,PITPNC1,GPM6A,SPARCL1,NFIA,CSGALNACT1,FMN2,BMPR1B,PARD3B,MACF1
1.364e-02	-4.29	ERBB signaling pathway	biological process	GO:0038127	66	2	18204	49	EFEMP1,NRG3
1.364e-02	-4.29	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	49	SLC1A2,SLC1A3
1.369e-02	-4.29	SFXNs	pfam domains	PF03820	5	1	17795	49	SFXN5
1.369e-02	-4.29	Aminotran_3	pfam domains	PF00202	5	1	17795	49	ETNPPL
1.369e-02	-4.29	Protocadherin	pfam domains	PF08374	5	1	17795	49	PCDH9
1.369e-02	-4.29	IP_trans	pfam domains	PF02121	5	1	17795	49	PITPNC1
1.369e-02	-4.29	FOLN	pfam domains	PF09289	5	1	17795	49	SPARCL1
1.379e-02	-4.28	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	7	19454	50	MACF1,SLC1A3,PON2,PRKCA,DTNA,PREX2,FMN2
1.381e-02	-4.28	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	5	16828	48	PRKCA,TNIK,NTRK2,FGFR3,BMPR1B
1.383e-02	-4.28	ATP binding	molecular function	GO:0005524	1467	9	18094	48	MAST4,TNIK,FGFR3,BMPR1B,ATP1A2,PRKCA,NTRK2,ATP13A4,ADCY2
1.392e-02	-4.27	meninges-meningioma	COSMIC cancer mutations	meninges-meningioma	327	4	16828	48	FGFR3,FMN2,ITPR2,NFIA
1.398e-02	-4.27	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	14	16828	48	MACF1,ADCY2,AQP4,SPARCL1,PON2,GLIS3,PTPRZ1,PREX2,CTNND2,FMN2,NPAS3,NFIA,PARD3B,FGFR3
1.398e-02	-4.27	embryonal	COSMIC cancer mutations	embryonal	2659	14	16828	48	AQP4,SPARCL1,ADCY2,MACF1,PON2,GLIS3,PREX2,PTPRZ1,NFIA,FMN2,NPAS3,CTNND2,FGFR3,PARD3B
1.398e-02	-4.27	AGC_KINASE_CTER	prosite domains	PS51285	55	2	12186	40	PRKCA,MAST4
1.399e-02	-4.27	PCDH20 (protocadherin 20)	protein interactions	64881	70	2	19454	50	MGAT4C,PON2
1.401e-02	-4.27	Neuronal System	REACTOME pathways	R-HSA-112316	349	4	10285	28	PRKCA,SLC1A2,ADCY2,SLC1A3
1.403e-02	-4.27	cell projection organization	biological process	GO:0030030	1200	8	18204	49	ABLIM1,TNIK,GPM6A,BMPR1B,NFIB,PREX2,CTNND2,PTPRZ1
1.405e-02	-4.27	monoatomic ion transport	biological process	GO:0006811	964	7	18204	49	ATP13A4,SFXN5,ITPR2,SLC1A3,GPM6A,ATP1A2,SLC1A2
1.408e-02	-4.26	seminoma	COSMIC cancer mutations	seminoma	700	6	16828	48	PRKCA,TNIK,PREX2,NTRK2,FGFR3,BMPR1B
1.418e-02	-4.26	skin-breast-other-nevus_sebaceous	COSMIC cancer mutations	skin-breast-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-upper_arm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_arm-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-other-lichenoid_keratosis	COSMIC cancer mutations	skin-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-hip-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-hip-other-seborrhoeic_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-shoulder-other-nevus_sebaceous	COSMIC cancer mutations	skin-shoulder-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-lower_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_back-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-forearm-other-lichenoid_keratosis	COSMIC cancer mutations	skin-forearm-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-face-other-lichenoid_keratosis	COSMIC cancer mutations	skin-face-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-lower_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-lower_leg-malignant_melanoma-superficial_spreading	5	1	16828	48	PREX2
1.418e-02	-4.26	skin-upper_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_leg-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	lichenoid_keratosis	COSMIC cancer mutations	lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-breast-other-lichenoid_keratosis	COSMIC cancer mutations	skin-breast-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-face-other-nevus_sebaceous	COSMIC cancer mutations	skin-face-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	monoclonal_gammopathy_of_undetermined_significance	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-flank-other-lichenoid_keratosis	COSMIC cancer mutations	skin-flank-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-chest-other-lichenoid_keratosis	COSMIC cancer mutations	skin-chest-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-forearm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-forearm-other-seborrhoeic_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-arm-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-arm-other-seborrhoeic_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-adnexal_tumour-syringocystadenoma_papilliferum	COSMIC cancer mutations	skin-adnexal_tumour-syringocystadenoma_papilliferum	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-scalp-other-nevus_sebaceous	COSMIC cancer mutations	skin-scalp-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	syringocystadenoma_papilliferum	COSMIC cancer mutations	syringocystadenoma_papilliferum	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-ear-other-nevus_sebaceous	COSMIC cancer mutations	skin-ear-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-lower_back-other-nevus_sebaceous	COSMIC cancer mutations	skin-lower_back-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-upper_back-other-lichenoid_keratosis	COSMIC cancer mutations	skin-upper_back-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-neck-other-lichenoid_keratosis	COSMIC cancer mutations	skin-neck-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-hand-other-lichenoid_keratosis	COSMIC cancer mutations	skin-hand-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-lower_leg-other-lichenoid_keratosis	COSMIC cancer mutations	skin-lower_leg-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-shoulder-other-lichenoid_keratosis	COSMIC cancer mutations	skin-shoulder-other-lichenoid_keratosis	5	1	16828	48	FGFR3
1.418e-02	-4.26	skin-neck-other-nevus_sebaceous	COSMIC cancer mutations	skin-neck-other-nevus_sebaceous	5	1	16828	48	FGFR3
1.421e-02	-4.25	Endothelins	Pathway Interaction DB	endothelinpathway	53	2	2226	8	ADCY2,PRKCA
1.433e-02	-4.25	NFIX (nuclear factor I X)	protein interactions	4784	198	3	19454	50	NFIB,NFIA,SOX5
1.433e-02	-4.25	CAMK2D (calcium/calmodulin dependent protein kinase II delta)	protein interactions	817	198	3	19454	50	PON2,ITPR2,FGFR3
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	TNIK,GPM6A
1.437e-02	-4.24	CRYBG1 (crystallin beta-gamma domain containing 1)	protein interactions	202	71	2	19454	50	CSGALNACT1,SPARCL1
1.440e-02	-4.24	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	8	16828	48	FGFR3,NTRK2,NFIB,MGAT4C,PRKCA,LIFR,CTNND2,TNIK
1.446e-02	-4.24	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	19	ATP1A2,SLC1A3
1.447e-02	-4.24	lung-carcinoid-endocrine_tumour-atypical	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour-atypical	508	5	16828	48	FGFR3,BMPR1B,NTRK2,TNIK,PRKCA
1.450e-02	-4.23	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	4	16828	48	PTPRZ1,PARD3B,ADCY2,NTM
1.455e-02	-4.23	Ion Channel and Phorbal Esters Signaling Pathway	SMPDB pathways	SMP0090032	5	1	1369	4	PRKCA
1.455e-02	-4.23	Corticotropin Activation of Cortisol Production	SMPDB pathways	SMP0000310	5	1	1369	4	ADCY2
1.458e-02	-4.23	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	47	16828	48	CDH20,PON2,NEBL,ATP1A2,LIFR,NTM,SLC1A3,PRKCA,NFIA,FMN2,QKI,CSGALNACT1,PTPRZ1,GLIS3,NTRK2,AQP4,PITPNC1,ATP13A4,NRG3,SOX5,MACF1,NFIB,PARD3B,TNIK,LSAMP,SPARCL1,ABLIM1,ADCY2,MGAT4C,HPSE2,PCDH9,NPAS3,BMPR1B,EFEMP1,PREX2,ZBTB20,GPM6A,ITPR2,NKAIN3,SLC1A2,NHSL1,FBXL7,FGFR3,SFXN5,MSI2,DPP10,CTNND2
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	47	16828	48	TNIK,PARD3B,NFIB,SOX5,MACF1,NRG3,PITPNC1,ATP13A4,AQP4,NTRK2,PTPRZ1,GLIS3,QKI,FMN2,CSGALNACT1,NFIA,PRKCA,SLC1A3,LIFR,NTM,ATP1A2,NEBL,CDH20,PON2,DPP10,CTNND2,MSI2,SFXN5,FBXL7,FGFR3,NHSL1,SLC1A2,GPM6A,ITPR2,ZBTB20,PREX2,EFEMP1,NPAS3,BMPR1B,PCDH9,HPSE2,MGAT4C,ADCY2,DTNA,ABLIM1,SPARCL1,LSAMP
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	47	16828	48	TNIK,PARD3B,NFIB,PITPNC1,NRG3,ATP13A4,AQP4,MACF1,SOX5,GLIS3,PTPRZ1,NTRK2,NFIA,CSGALNACT1,QKI,FMN2,PRKCA,SLC1A3,NEBL,ATP1A2,NTM,LIFR,PON2,CDH20,MSI2,SFXN5,CTNND2,DPP10,NHSL1,SLC1A2,FGFR3,FBXL7,ITPR2,GPM6A,ZBTB20,PREX2,EFEMP1,PCDH9,BMPR1B,NPAS3,MGAT4C,HPSE2,ABLIM1,DTNA,SPARCL1,ADCY2,LSAMP
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	47	16828	48	SLC1A2,NHSL1,FBXL7,FGFR3,SFXN5,MSI2,DPP10,CTNND2,EFEMP1,PREX2,ZBTB20,GPM6A,ITPR2,MGAT4C,HPSE2,PCDH9,NPAS3,BMPR1B,LSAMP,SPARCL1,DTNA,ABLIM1,ADCY2,PARD3B,NFIB,TNIK,PTPRZ1,GLIS3,NTRK2,AQP4,NRG3,ATP13A4,PITPNC1,SOX5,MACF1,SLC1A3,PRKCA,NFIA,QKI,FMN2,CSGALNACT1,CDH20,PON2,ATP1A2,NEBL,LIFR,NTM
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	47	16828	48	HPSE2,MGAT4C,BMPR1B,NPAS3,PCDH9,LSAMP,ADCY2,SPARCL1,ABLIM1,DTNA,FGFR3,FBXL7,SLC1A2,NHSL1,CTNND2,DPP10,SFXN5,MSI2,PREX2,EFEMP1,ZBTB20,ITPR2,GPM6A,SLC1A3,PRKCA,CSGALNACT1,FMN2,QKI,NFIA,PON2,CDH20,NTM,LIFR,NEBL,ATP1A2,NFIB,PARD3B,TNIK,NTRK2,GLIS3,PTPRZ1,MACF1,SOX5,AQP4,PITPNC1,NRG3,ATP13A4
1.474e-02	-4.22	classic	COSMIC cancer mutations	classic	14774	47	16828	48	LSAMP,ADCY2,DTNA,ABLIM1,SPARCL1,HPSE2,MGAT4C,NPAS3,BMPR1B,PCDH9,ZBTB20,EFEMP1,PREX2,GPM6A,ITPR2,FBXL7,FGFR3,NHSL1,SLC1A2,DPP10,CTNND2,MSI2,SFXN5,CDH20,PON2,LIFR,NTM,ATP1A2,NEBL,PRKCA,SLC1A3,FMN2,QKI,CSGALNACT1,NFIA,NTRK2,PTPRZ1,GLIS3,SOX5,MACF1,ATP13A4,PITPNC1,NRG3,AQP4,NFIB,PARD3B,TNIK
1.474e-02	-4.22	NEBU	smart domains	SM00227	4	1	9717	36	NEBL
1.476e-02	-4.22	PPP3CC (protein phosphatase 3 catalytic subunit gamma)	protein interactions	5533	72	2	19454	50	BMPR1B,PARD3B
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	GPM6A,TNIK
1.490e-02	-4.21	medulla	COSMIC cancer mutations	medulla	14778	47	16828	48	FBXL7,FGFR3,SLC1A2,NHSL1,DPP10,CTNND2,SFXN5,MSI2,PREX2,EFEMP1,ZBTB20,GPM6A,ITPR2,HPSE2,MGAT4C,NPAS3,BMPR1B,PCDH9,LSAMP,ADCY2,SPARCL1,DTNA,ABLIM1,NFIB,PARD3B,TNIK,NTRK2,PTPRZ1,GLIS3,SOX5,MACF1,AQP4,NRG3,ATP13A4,PITPNC1,SLC1A3,PRKCA,FMN2,QKI,CSGALNACT1,NFIA,CDH20,PON2,LIFR,NTM,NEBL,ATP1A2
1.492e-02	-4.21	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	3	19454	50	ATP1A2,PRKCA,DTNA
1.494e-02	-4.20	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	9	16828	48	MACF1,CTNND2,ITPR2,PCDH9,ATP13A4,ATP1A2,FGFR3,HPSE2,PARD3B
1.495e-02	-4.20	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	47	16828	48	AQP4,NRG3,ATP13A4,PITPNC1,MACF1,SOX5,GLIS3,PTPRZ1,NTRK2,TNIK,PARD3B,NFIB,NEBL,ATP1A2,NTM,LIFR,PON2,CDH20,NFIA,CSGALNACT1,QKI,FMN2,SLC1A3,PRKCA,ITPR2,GPM6A,EFEMP1,PREX2,ZBTB20,SFXN5,MSI2,CTNND2,DPP10,SLC1A2,NHSL1,FGFR3,FBXL7,SPARCL1,ABLIM1,DTNA,ADCY2,LSAMP,PCDH9,BMPR1B,NPAS3,MGAT4C,HPSE2
1.504e-02	-4.20	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	25	16828	48	PON2,ADCY2,LIFR,ABLIM1,NEBL,ATP1A2,DTNA,SPARCL1,SLC1A3,CSGALNACT1,NPAS3,NTRK2,ZBTB20,GLIS3,PREX2,PTPRZ1,MACF1,ITPR2,NKAIN3,SOX5,NRG3,ATP13A4,NFIB,FGFR3,CTNND2
1.505e-02	-4.20	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	7	16828	48	MACF1,CTNND2,LIFR,ADCY2,ATP13A4,PREX2,MGAT4C
1.511e-02	-4.19	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	21	ITPR2,ADCY2,PRKCA
1.511e-02	-4.19	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	21	PRKCA,ADCY2,ITPR2
1.512e-02	-4.19	FEV (FEV transcription factor, ETS family member)	protein interactions	54738	202	3	19454	50	NFIA,NFIB,SOX5
1.521e-02	-4.19	plasma membrane region	cellular component	GO:0098590	1278	8	19108	49	ATP1A2,SLC1A2,MACF1,PARD3B,GPM6A,AQP4,SLC1A3,TNIK
1.528e-02	-4.18	atypical	COSMIC cancer mutations	atypical	515	5	16828	48	TNIK,PRKCA,BMPR1B,FGFR3,NTRK2
1.528e-02	-4.18	neoplasm	COSMIC cancer mutations	neoplasm	14787	47	16828	48	GLIS3,PTPRZ1,NTRK2,ATP13A4,NRG3,AQP4,MACF1,SOX5,PARD3B,NFIB,TNIK,PON2,CDH20,NEBL,ATP1A2,NTM,LIFR,PRKCA,SLC1A3,NFIA,CSGALNACT1,FMN2,QKI,ZBTB20,PREX2,EFEMP1,ITPR2,NKAIN3,GPM6A,NHSL1,SLC1A2,FGFR3,FBXL7,MSI2,SFXN5,CTNND2,DPP10,LSAMP,ABLIM1,DTNA,SPARCL1,ADCY2,MGAT4C,HPSE2,PCDH9,BMPR1B,NPAS3
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	SOX1 (SRY-box transcription factor 1)	protein interactions	6656	6	1	19454	50	SOX5
1.532e-02	-4.18	LIF (LIF interleukin 6 family cytokine)	protein interactions	3976	6	1	19454	50	LIFR
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	ARMS2 (age-related maculopathy susceptibility 2)	protein interactions	387715	6	1	19454	50	PRKCA
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	ADCY1 (adenylate cyclase 1)	protein interactions	107	6	1	19454	50	ADCY2
1.532e-02	-4.18	FGF23 (fibroblast growth factor 23)	protein interactions	8074	6	1	19454	50	FGFR3
1.532e-02	-4.18	FGF18 (fibroblast growth factor 18)	protein interactions	8817	6	1	19454	50	FGFR3
1.532e-02	-4.18	Fancl (Fanconi anemia, complementation group L)	protein interactions	67030	6	1	19454	50	BMPR1B
1.532e-02	-4.18	Rhod (ras homolog family member D)	protein interactions	11854	6	1	19454	50	BMPR1B
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	Map2k3 (mitogen-activated protein kinase kinase 3)	protein interactions	26397	6	1	19454	50	BMPR1B
1.532e-02	-4.18	SOX11 (SRY-box transcription factor 11)	protein interactions	6664	6	1	19454	50	SOX5
1.532e-02	-4.18	FGF6 (fibroblast growth factor 6)	protein interactions	2251	6	1	19454	50	FGFR3
1.532e-02	-4.18	Csnk1d (casein kinase 1, delta)	protein interactions	64462	6	1	19454	50	PRKCA
1.532e-02	-4.18	GDF6 (growth differentiation factor 6)	protein interactions	392255	6	1	19454	50	BMPR1B
1.538e-02	-4.17	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	26	16828	48	NFIA,FMN2,BMPR1B,PRKCA,HPSE2,ATP1A2,ABLIM1,LIFR,ADCY2,NTM,PON2,TNIK,DPP10,CTNND2,FGFR3,NFIB,ATP13A4,NRG3,PITPNC1,SOX5,ITPR2,MACF1,PREX2,PTPRZ1,ZBTB20,NTRK2
1.538e-02	-4.17	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	26	16828	48	TNIK,DPP10,CTNND2,FGFR3,NFIB,PITPNC1,NRG3,ATP13A4,SOX5,ITPR2,MACF1,PREX2,PTPRZ1,ZBTB20,NTRK2,NFIA,FMN2,BMPR1B,PRKCA,HPSE2,ATP1A2,ABLIM1,LIFR,NTM,ADCY2,PON2
1.547e-02	-4.17	cell-cell contact zone	cellular component	GO:0044291	74	2	19108	49	PCDH9,ATP1A2
1.550e-02	-4.17	LIM	pfam domains	PF00412	69	2	17795	49	ABLIM1,NEBL
1.552e-02	-4.17	NFIC (nuclear factor I C)	protein interactions	4782	204	3	19454	50	NFIB,NFIA,SOX5
1.552e-02	-4.17	CASK (calcium/calmodulin dependent serine protein kinase)	protein interactions	8573	204	3	19454	50	ABLIM1,DTNA,PARD3B
1.554e-02	-4.16	ErbB Signaling Pathway	WikiPathways	WP673	54	2	5310	19	NRG3,PRKCA
1.554e-02	-4.16	bone development	biological process	GO:0060348	195	3	18204	49	FGFR3,CSGALNACT1,BMPR1B
1.554e-02	-4.16	CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1)	protein interactions	781	74	2	19454	50	GPM6A,PON2
1.563e-02	-4.16	PDZ	smart domains	SM00228	143	3	9717	36	PARD3B,MAST4,PREX2
1.564e-02	-4.16	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	19	ITPR2,PRKCA,ADCY2
1.576e-02	-4.15	Znf_LIM	interpro domains	IPR001781	71	2	18521	50	NEBL,ABLIM1
1.581e-02	-4.15	ciliary neurotrophic factor receptor binding	molecular function	GO:0005127	6	1	18094	48	LIFR
1.581e-02	-4.15	steroid hormone binding	molecular function	GO:1990239	6	1	18094	48	ATP1A2
1.581e-02	-4.15	arylesterase activity	molecular function	GO:0004064	6	1	18094	48	PON2
1.581e-02	-4.15	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular function	GO:0047238	6	1	18094	48	CSGALNACT1
1.584e-02	-4.15	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	47	16828	48	NTRK2,GLIS3,PTPRZ1,MACF1,SOX5,AQP4,ATP13A4,NRG3,PITPNC1,NFIB,PARD3B,TNIK,PON2,CDH20,NTM,LIFR,NEBL,ATP1A2,SLC1A3,PRKCA,CSGALNACT1,FMN2,QKI,NFIA,EFEMP1,PREX2,ZBTB20,ITPR2,NKAIN3,GPM6A,FGFR3,FBXL7,SLC1A2,NHSL1,CTNND2,DPP10,SFXN5,LSAMP,ADCY2,SPARCL1,ABLIM1,DTNA,HPSE2,MGAT4C,BMPR1B,NPAS3,PCDH9
1.584e-02	-4.15	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	47	16828	48	NFIB,PARD3B,TNIK,GLIS3,PTPRZ1,NTRK2,AQP4,PITPNC1,ATP13A4,NRG3,MACF1,SOX5,SLC1A3,PRKCA,NFIA,CSGALNACT1,FMN2,QKI,PON2,CDH20,NEBL,ATP1A2,NTM,LIFR,SLC1A2,NHSL1,FGFR3,FBXL7,SFXN5,CTNND2,DPP10,EFEMP1,PREX2,ZBTB20,NKAIN3,ITPR2,GPM6A,MGAT4C,HPSE2,PCDH9,BMPR1B,NPAS3,LSAMP,SPARCL1,ABLIM1,DTNA,ADCY2
1.597e-02	-4.14	protein localization to plasma membrane	biological process	GO:0072659	197	3	18204	49	MACF1,DPP10,TNIK
1.598e-02	-4.14	cell adhesion molecule binding	molecular function	GO:0050839	560	5	18094	48	CDH20,MACF1,PRKCA,CTNND2,PTPRZ1
1.604e-02	-4.13	type II pneumocyte differentiation	biological process	GO:0060510	6	1	18204	49	NFIB
1.604e-02	-4.13	fused antrum stage	biological process	GO:0048165	6	1	18204	49	BMPR1B
1.604e-02	-4.13	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	49	SLC1A3
1.604e-02	-4.13	establishment of meiotic spindle localization	biological process	GO:0051295	6	1	18204	49	FMN2
1.604e-02	-4.13	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	49	NRG3
1.604e-02	-4.13	asymmetric neuroblast division	biological process	GO:0055059	6	1	18204	49	SOX5
1.604e-02	-4.13	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	49	AQP4
1.604e-02	-4.13	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological process	GO:0106071	6	1	18204	49	PRKCA
1.604e-02	-4.13	mammary gland formation	biological process	GO:0060592	6	1	18204	49	NRG3
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	ITPR2
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	ITPR2
1.609e-02	-4.13	EF-hand_dom_typ2	interpro domains	IPR015154	6	1	18521	50	DTNA
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	ITPR2
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	ITPR2
1.609e-02	-4.13	Desmoplakin_SH3	interpro domains	IPR041615	6	1	18521	50	MACF1
1.609e-02	-4.13	GAR_dom_sf	interpro domains	IPR036534	6	1	18521	50	MACF1
1.609e-02	-4.13	Peptidase_S9B_N	interpro domains	IPR002469	6	1	18521	50	DPP10
1.609e-02	-4.13	GAR_dom	interpro domains	IPR003108	6	1	18521	50	MACF1
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	ITPR2
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	EF-hand_dom_typ1	interpro domains	IPR015153	6	1	18521	50	DTNA
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	Adcy_conserved_dom	interpro domains	IPR009398	6	1	18521	50	ADCY2
1.615e-02	-4.13	Long-term potentiation	KEGG pathways	ko04720	67	2	7161	21	ITPR2,PRKCA
1.615e-02	-4.13	Long-term potentiation	KEGG pathways	hsa04720	67	2	7161	21	PRKCA,ITPR2
1.623e-02	-4.12	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	28	NTRK2
1.631e-02	-4.12	AA_TRANSFER_CLASS_3	prosite domains	PS00600	5	1	12186	40	ETNPPL
1.635e-02	-4.11	MIR200A (microRNA 200a)	protein interactions	406983	76	2	19454	50	MSI2,QKI
1.640e-02	-4.11	positive regulation of ERK1 and ERK2 cascade	biological process	GO:0070374	199	3	18204	49	FGFR3,PRKCA,NTRK2
1.641e-02	-4.11	GAS2	pfam domains	PF02187	6	1	17795	49	MACF1
1.641e-02	-4.11	DPPIV_N	pfam domains	PF00930	6	1	17795	49	DPP10
1.641e-02	-4.11	Plectin	pfam domains	PF00681	6	1	17795	49	MACF1
1.641e-02	-4.11	Adcy_cons_dom	pfam domains	PF06327	6	1	17795	49	ADCY2
1.641e-02	-4.11	RIH_assoc	pfam domains	PF08454	6	1	17795	49	ITPR2
1.641e-02	-4.11	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	49	ITPR2
1.641e-02	-4.11	RYDR_ITPR	pfam domains	PF01365	6	1	17795	49	ITPR2
1.641e-02	-4.11	EF-hand_2	pfam domains	PF09068	6	1	17795	49	DTNA
1.641e-02	-4.11	EF-hand_3	pfam domains	PF09069	6	1	17795	49	DTNA
1.641e-02	-4.11	SH3_10	pfam domains	PF17902	6	1	17795	49	MACF1
1.652e-02	-4.10	neuron fate commitment	biological process	GO:0048663	73	2	18204	49	NFIB,NFIA
1.652e-02	-4.10	vasculogenesis	biological process	GO:0001570	73	2	18204	49	NTRK2,QKI
1.675e-02	-4.09	TLE1 (TLE family member 1, transcriptional corepressor)	protein interactions	7088	210	3	19454	50	NFIA,NFIB,SOX5
1.689e-02	-4.08	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	4	10285	28	MACF1,FGFR3,QKI,NRG3
1.695e-02	-4.08	positive regulation of gliogenesis	biological process	GO:0014015	74	2	18204	49	PTPRZ1,QKI
1.700e-02	-4.07	skin-lower_back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-lower_back-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-upper_leg-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-upper_leg-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-back-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-back-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-arm-epidermal_nevus	COSMIC cancer mutations	skin-arm-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-trunk-epidermal_nevus	COSMIC cancer mutations	skin-trunk-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	lentiginous_nevus	COSMIC cancer mutations	lentiginous_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-adnexal_tumour-trichoblastoma	COSMIC cancer mutations	skin-adnexal_tumour-trichoblastoma	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-head_neck-epidermal_nevus	COSMIC cancer mutations	skin-head_neck-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-epidermal_nevus	COSMIC cancer mutations	skin-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-head_neck-malignant_melanoma	COSMIC cancer mutations	skin-head_neck-malignant_melanoma	6	1	16828	48	PREX2
1.700e-02	-4.07	collecting_duct_carcinoma	COSMIC cancer mutations	collecting_duct_carcinoma	6	1	16828	48	FGFR3
1.700e-02	-4.07	kidney-carcinoma-collecting_duct_carcinoma	COSMIC cancer mutations	kidney-carcinoma-collecting_duct_carcinoma	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-face-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-face-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-in_situ_epithelial_neoplasm-Bowen_disease	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-Bowen_disease	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-forearm-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-forearm-malignant_melanoma-superficial_spreading	6	1	16828	48	PREX2
1.700e-02	-4.07	skin-lower_leg-epidermal_nevus	COSMIC cancer mutations	skin-lower_leg-epidermal_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-benign_melanocytic_nevus-lentiginous_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus-lentiginous_nevus	6	1	16828	48	FGFR3
1.700e-02	-4.07	autonomic_ganglia-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-paraganglioma-benign	6	1	16828	48	NHSL1
1.700e-02	-4.07	skin-flank-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-flank-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-abdomen-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-abdomen-other-seborrhoeic_keratosis	6	1	16828	48	FGFR3
1.700e-02	-4.07	skin-in_situ_epithelial_neoplasm-actinic_keratosis	COSMIC cancer mutations	skin-in_situ_epithelial_neoplasm-actinic_keratosis	6	1	16828	48	FGFR3
1.701e-02	-4.07	Immunoglobulins	gene3d domains	2.60.40.10	721	6	14470	42	FGFR3,LSAMP,NTM,LIFR,NTRK2,PTPRZ1
1.705e-02	-4.07	HAD_sf	interpro domains	IPR023214	74	2	18521	50	ATP13A4,ATP1A2
1.709e-02	-4.07	human chr4q22.3	chromosome location	human chr4q22.3	9	1	26134	50	BMPR1B
1.710e-02	-4.07	head development	biological process	GO:0060322	774	6	18204	49	PCDH9,NFIB,NRG3,SLC1A2,NTRK2,ATP1A2
1.711e-02	-4.07	PITRANSFER	prints domains	PR00391	5	1	5227	18	PITPNC1
1.711e-02	-4.07	Oncogenic MAPK signaling	REACTOME pathways	R-HSA-6802957	74	2	10285	28	MACF1,QKI
1.715e-02	-4.07	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	29	16828	48	SLC1A3,NPAS3,FMN2,QKI,CSGALNACT1,PON2,LIFR,ADCY2,ATP1A2,DTNA,NEBL,ABLIM1,SPARCL1,NFIB,PARD3B,FGFR3,CTNND2,TNIK,NTRK2,ZBTB20,PTPRZ1,PREX2,GLIS3,SOX5,MACF1,ITPR2,NKAIN3,ATP13A4,NRG3
1.716e-02	-4.07	MARCKS (myristoylated alanine rich protein kinase C substrate)	protein interactions	4082	588	5	19454	50	ABLIM1,DTNA,MACF1,SLC1A3,PRKCA
1.717e-02	-4.06	SDC4 (syndecan 4)	protein interactions	6385	78	2	19454	50	FGFR3,PRKCA
1.717e-02	-4.06	PRR12 (proline rich 12)	protein interactions	57479	78	2	19454	50	NFIB,NFIA
1.717e-02	-4.06	Nedd4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	25489	78	2	19454	50	NTRK2,BMPR1B
1.717e-02	-4.06	ANKRD40 (ankyrin repeat domain 40)	protein interactions	91369	78	2	19454	50	MSI2,SOX5
1.717e-02	-4.06	ATP2B3 (ATPase plasma membrane Ca2+ transporting 3)	protein interactions	492	78	2	19454	50	CSGALNACT1,GPM6A
1.717e-02	-4.06	MIR34C (microRNA 34c)	protein interactions	407042	78	2	19454	50	QKI,MSI2
1.729e-02	-4.06	Plakin repeat	gene3d domains	3.90.1290.10	6	1	14470	42	MACF1
1.729e-02	-4.06	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	42	ITPR2
1.729e-02	-4.06	Gas2-like domain	gene3d domains	3.30.920.20	6	1	14470	42	MACF1
1.729e-02	-4.06	Dipeptidylpeptidase IV, N-terminal domain	gene3d domains	2.140.10.30	6	1	14470	42	DPP10
1.744e-02	-4.05	Dopamine Activation of Neurological Reward System	SMPDB pathways	SMP0000308	6	1	1369	4	ADCY2
1.744e-02	-4.05	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	SMPDB pathways	SMP0000343	6	1	1369	4	ADCY2
1.744e-02	-4.05	Phospholipase C Signaling Pathway	SMPDB pathways	SMP0063783	6	1	1369	4	PRKCA
1.747e-02	-4.05	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	M00058	6	1	7161	21	CSGALNACT1
1.747e-02	-4.05	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	KEGG pathways	hsa_M00058	6	1	7161	21	CSGALNACT1
1.748e-02	-4.05	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	48	PREX2,SLC1A2,ATP13A4,FMN2,MACF1,ITPR2,DPP10
1.748e-02	-4.05	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	7	16828	48	FMN2,MACF1,ITPR2,DPP10,SLC1A2,PREX2,ATP13A4
1.759e-02	-4.04	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	26	16828	48	ABLIM1,NTM,ADCY2,LIFR,CDH20,QKI,FMN2,NPAS3,MGAT4C,SLC1A3,HPSE2,PITPNC1,NRG3,MACF1,SOX5,GPM6A,PREX2,EFEMP1,ZBTB20,SFXN5,CTNND2,SLC1A2,NHSL1,FGFR3,FBXL7,PARD3B
1.761e-02	-4.04	NCK1 (NCK adaptor protein 1)	protein interactions	4690	214	3	19454	50	NHSL1,NTRK2,TNIK
1.762e-02	-4.04	TRAF2 (TNF receptor associated factor 2)	protein interactions	7186	592	5	19454	50	EFEMP1,SOX5,TNIK,ABLIM1,NEBL
1.765e-02	-4.04	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	19	ADCY2,ITPR2,PRKCA
1.767e-02	-4.04	mannosyl-glycoprotein N-acetylglucosaminyltransferases	BIOCYC pathways	META_PWY-7426	8	1	902	2	MGAT4C
1.767e-02	-4.04	adenyl ribonucleotide binding	molecular function	GO:0032559	1528	9	18094	48	NTRK2,ATP13A4,ADCY2,PRKCA,TNIK,FGFR3,BMPR1B,ATP1A2,MAST4
1.782e-02	-4.03	cerebellar mossy fiber	cellular component	GO:0044300	7	1	19108	49	NFIB
1.783e-02	-4.03	other	COSMIC cancer mutations	other	14843	47	16828	48	CDH20,PON2,LSAMP,LIFR,ADCY2,NTM,NEBL,ATP1A2,DTNA,ABLIM1,SPARCL1,HPSE2,PRKCA,SLC1A3,MGAT4C,NPAS3,QKI,FMN2,CSGALNACT1,BMPR1B,NFIA,PCDH9,NTRK2,ZBTB20,EFEMP1,PTPRZ1,PREX2,GLIS3,GPM6A,SOX5,MACF1,ITPR2,NKAIN3,ATP13A4,NRG3,AQP4,NFIB,PARD3B,FBXL7,FGFR3,NHSL1,SLC1A2,DPP10,CTNND2,MSI2,SFXN5,TNIK
1.786e-02	-4.03	Smad7 (SMAD family member 7)	protein interactions	17131	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	RGMB (repulsive guidance molecule BMP co-receptor b)	protein interactions	285704	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Fbxo3 (F-box protein 3)	protein interactions	57443	7	1	19454	50	BMPR1B
1.786e-02	-4.03	FGF5 (fibroblast growth factor 5)	protein interactions	2250	7	1	19454	50	FGFR3
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	Uhmk1 (U2AF homology motif (UHM) kinase 1)	protein interactions	16589	7	1	19454	50	BMPR1B
1.786e-02	-4.03	SASH3 (SAM and SH3 domain containing 3)	protein interactions	54440	7	1	19454	50	BMPR1B
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.789e-02	-4.02	PROTEIN_KINASE_ST	prosite domains	PS00108	308	4	12186	40	TNIK,PRKCA,BMPR1B,MAST4
1.793e-02	-4.02	large_cell	COSMIC cancer mutations	large_cell	14845	47	16828	48	ZBTB20,EFEMP1,PREX2,ITPR2,GPM6A,NHSL1,SLC1A2,FGFR3,FBXL7,MSI2,SFXN5,CTNND2,DPP10,LSAMP,ABLIM1,DTNA,SPARCL1,ADCY2,MGAT4C,HPSE2,PCDH9,BMPR1B,NPAS3,GLIS3,PTPRZ1,NTRK2,ATP13A4,PITPNC1,NRG3,AQP4,MACF1,SOX5,PARD3B,NFIB,TNIK,PON2,CDH20,NEBL,ATP1A2,NTM,LIFR,PRKCA,SLC1A3,NFIA,CSGALNACT1,FMN2,QKI
1.801e-02	-4.02	BCL9 (BCL9 transcription coactivator)	protein interactions	607	80	2	19454	50	NFIA,NFIB
1.801e-02	-4.02	GJB1 (gap junction protein beta 1)	protein interactions	2705	80	2	19454	50	MSI2,PRKCA
1.804e-02	-4.01	ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)	protein interactions	490	216	3	19454	50	NTRK2,FGFR3,PRKCA
1.826e-02	-4.00	GFAP (glial fibrillary acidic protein)	protein interactions	2670	217	3	19454	50	ABLIM1,NKAIN3,PRKCA
1.827e-02	-4.00	neural retina development	biological process	GO:0003407	77	2	18204	49	NTRK2,GPM6A
1.827e-02	-4.00	BMP signaling pathway	biological process	GO:0030509	77	2	18204	49	NFIA,BMPR1B
1.827e-02	-4.00	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	49	MACF1,NTRK2
1.829e-02	-4.00	cellular process	biological process	GO:0009987	14996	46	18204	49	SOX5,AQP4,FGFR3,PTPRZ1,MGAT4C,NHSL1,EFEMP1,CDH20,MAST4,NTRK2,PRKCA,SPARCL1,PCDH9,DTNA,ATP1A2,NTM,FBXL7,PITPNC1,SLC1A3,PARD3B,SFXN5,ADCY2,DPP10,BMPR1B,NRG3,NEBL,CTNND2,PREX2,LIFR,NFIB,ATP13A4,ABLIM1,MSI2,SLC1A2,ZBTB20,HPSE2,TNIK,GPM6A,QKI,MACF1,ITPR2,NFIA,LSAMP,CSGALNACT1,FMN2,GLIS3
1.836e-02	-4.00	plasma membrane protein complex	cellular component	GO:0098797	600	5	19108	49	DPP10,BMPR1B,ATP1A2,CDH20,PRKCA
1.840e-02	-4.00	actin filament binding	molecular function	GO:0051015	211	3	18094	48	NEBL,ABLIM1,MACF1
1.841e-02	-3.99	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	COSMIC cancer mutations	central_nervous_system-brain-glioma-oligodendroglioma_Grade_II	73	2	16828	48	MACF1,FGFR3
1.843e-02	-3.99	phosphatidic acid transfer activity	molecular function	GO:1990050	7	1	18094	48	PITPNC1
1.843e-02	-3.99	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	48	ATP1A2
1.843e-02	-3.99	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	48	ATP1A2
1.843e-02	-3.99	SOX17 (SRY-box transcription factor 17)	protein interactions	64321	81	2	19454	50	NFIB,NFIA
1.844e-02	-3.99	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	49	MACF1,NTRK2,QKI,PTPRZ1
1.858e-02	-3.99	nipple	COSMIC cancer mutations	nipple	197	3	16828	48	EFEMP1,BMPR1B,FMN2
1.858e-02	-3.99	skin-nipple-malignant_melanoma	COSMIC cancer mutations	skin-nipple-malignant_melanoma	197	3	16828	48	FMN2,BMPR1B,EFEMP1
1.867e-02	-3.98	transmembrane transport	biological process	GO:0055085	1264	8	18204	49	SLC1A2,ATP1A2,GPM6A,SLC1A3,AQP4,ITPR2,ATP13A4,SFXN5
1.869e-02	-3.98	post-embryonic eye morphogenesis	biological process	GO:0048050	7	1	18204	49	EFEMP1
1.869e-02	-3.98	anterior commissure morphogenesis	biological process	GO:0021960	7	1	18204	49	NFIB
1.869e-02	-3.98	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	49	PTPRZ1
1.869e-02	-3.98	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	49	NRG3
1.869e-02	-3.98	parallel actin filament bundle assembly	biological process	GO:0030046	7	1	18204	49	FMN2
1.869e-02	-3.98	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	49	QKI
1.869e-02	-3.98	chromosome movement towards spindle pole	biological process	GO:0051305	7	1	18204	49	FMN2
1.869e-02	-3.98	regulation of epithelial cell proliferation involved in lung morphogenesis	biological process	GO:2000794	7	1	18204	49	NFIB
1.869e-02	-3.98	negative regulation of mesenchymal cell proliferation	biological process	GO:0072201	7	1	18204	49	NFIB
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.875e-02	-3.98	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	1	18521	50	SPARCL1
1.875e-02	-3.98	GS_dom	interpro domains	IPR003605	7	1	18521	50	BMPR1B
1.875e-02	-3.98	Hematopoietin_rcpt_Gp130_CS	interpro domains	IPR003529	7	1	18521	50	LIFR
1.875e-02	-3.98	Plectin_repeat	interpro domains	IPR001101	7	1	18521	50	MACF1
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Plakin_repeat_sf	interpro domains	IPR035915	7	1	18521	50	MACF1
1.882e-02	-3.97	HAD-like_sf	interpro domains	IPR036412	78	2	18521	50	ATP1A2,ATP13A4
1.886e-02	-3.97	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	3	5310	19	SLC1A3,NTRK2,AQP4
1.886e-02	-3.97	GSC (goosecoid homeobox)	protein interactions	145258	82	2	19454	50	SOX5,NFIA
1.886e-02	-3.97	NR2C1 (nuclear receptor subfamily 2 group C member 1)	protein interactions	7181	82	2	19454	50	NFIB,NFIA
1.889e-02	-3.97	oligodendroglioma_Grade_II	COSMIC cancer mutations	oligodendroglioma_Grade_II	74	2	16828	48	FGFR3,MACF1
1.891e-02	-3.97	FGFR3b ligand binding and activation	REACTOME pathways	R-HSA-190371	7	1	10285	28	FGFR3
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.898e-02	-3.96	Cysteine Rich Protein	gene3d domains	2.10.110.10	73	2	14470	42	NEBL,ABLIM1
1.909e-02	-3.96	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	48	SLC1A2,SLC1A3
1.910e-02	-3.96	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia	1440	9	16828	48	LIFR,FMN2,CTNND2,MACF1,NEBL,FGFR3,PREX2,PTPRZ1,CDH20
1.910e-02	-3.96	hairy_cell_leukaemia	COSMIC cancer mutations	hairy_cell_leukaemia	1440	9	16828	48	FGFR3,PTPRZ1,PREX2,CDH20,FMN2,LIFR,CTNND2,MACF1,NEBL
1.912e-02	-3.96	SPARC_Ca_bdg	pfam domains	PF10591	7	1	17795	49	SPARCL1
1.912e-02	-3.96	TGF_beta_GS	pfam domains	PF08515	7	1	17795	49	BMPR1B
1.917e-02	-3.95	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	49	QKI,PTPRZ1
1.930e-02	-3.95	PAX2 (paired box 2)	protein interactions	5076	83	2	19454	50	NFIA,NFIB
1.930e-02	-3.95	TM2D3 (TM2 domain containing 3)	protein interactions	80213	83	2	19454	50	PON2,FGFR3
1.930e-02	-3.95	DNM3 (dynamin 3)	protein interactions	26052	83	2	19454	50	FGFR3,GPM6A
1.944e-02	-3.94	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	5	18094	48	ITPR2,SLC1A3,ATP1A2,GPM6A,SLC1A2
1.947e-02	-3.94	HAD superfamily/HAD-like	gene3d domains	3.40.50.1000	74	2	14470	42	ATP1A2,ATP13A4
1.954e-02	-3.94	GAR	prosite domains	PS51460	6	1	12186	40	MACF1
1.955e-02	-3.93	intracellular chemical homeostasis	biological process	GO:0055082	581	5	18204	49	ATP1A2,AQP4,SLC1A3,ATP13A4,ZBTB20
1.966e-02	-3.93	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	48	MACF1,CTNND2,PCDH9,PREX2
1.974e-02	-3.93	Tyr_kinase_cat_dom	interpro domains	IPR020635	80	2	18521	50	FGFR3,NTRK2
1.976e-02	-3.92	FBXO2 (F-box protein 2)	protein interactions	26232	403	4	19454	50	LIFR,FGFR3,NTM,PCDH9
1.980e-02	-3.92	nevus_sebaceous	COSMIC cancer mutations	nevus_sebaceous	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-other-nevus_sebaceous	COSMIC cancer mutations	skin-other-nevus_sebaceous	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-shoulder-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-shoulder-other-seborrhoeic_keratosis	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-upper_leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-nodular	7	1	16828	48	PREX2
1.980e-02	-3.92	skin-face-malignant_melanoma-nodular	COSMIC cancer mutations	skin-face-malignant_melanoma-nodular	7	1	16828	48	PREX2
1.980e-02	-3.92	skin-chest-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-chest-other-seborrhoeic_keratosis	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-adnexal_tumour-trichilemmoma	COSMIC cancer mutations	skin-adnexal_tumour-trichilemmoma	7	1	16828	48	FGFR3
1.980e-02	-3.92	urinary_tract-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma-transitional_cell_carcinoma	7	1	16828	48	FGFR3
1.980e-02	-3.92	trichilemmoma	COSMIC cancer mutations	trichilemmoma	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-neck-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-neck-other-seborrhoeic_keratosis	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-benign_melanocytic_nevus-compound	COSMIC cancer mutations	skin-benign_melanocytic_nevus-compound	7	1	16828	48	FGFR3
1.980e-02	-3.92	skin-face-adnexal_tumour-malignant_adnexal_tumour	COSMIC cancer mutations	skin-face-adnexal_tumour-malignant_adnexal_tumour	7	1	16828	48	FGFR3
1.982e-02	-3.92	Regulation of insulin secretion	REACTOME pathways	R-HSA-422356	80	2	10285	28	PRKCA,ITPR2
1.991e-02	-3.92	FGFR1 (fibroblast growth factor receptor 1)	protein interactions	2260	611	5	19454	50	NHSL1,FGFR3,DTNA,TNIK,ABLIM1
2.002e-02	-3.91	YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)	protein interactions	7533	1083	7	19454	50	PITPNC1,ABLIM1,FMN2,PARD3B,MAST4,NHSL1,MACF1
2.008e-02	-3.91	KLF3 (KLF transcription factor 3)	protein interactions	51274	225	3	19454	50	SOX5,NFIA,NFIB
2.008e-02	-3.91	FOXC1 (forkhead box C1)	protein interactions	2296	225	3	19454	50	NFIB,NFIA,SOX5
2.009e-02	-3.91	adult locomotory behavior	biological process	GO:0008344	81	2	18204	49	PREX2,ATP1A2
2.018e-02	-3.90	SSBP3 (single stranded DNA binding protein 3)	protein interactions	23648	85	2	19454	50	NFIA,NFIB
2.032e-02	-3.90	g-Secretase Mediated ErbB4 Signalling Pathway	SMPDB pathways	SMP0089975	7	1	1369	4	PRKCA
2.032e-02	-3.90	Vasopressin Regulation of Water Homeostasis	SMPDB pathways	SMP0000322	7	1	1369	4	ADCY2
2.034e-02	-3.90	HFE-transferrin receptor complex	cellular component	GO:1990712	8	1	19108	49	BMPR1B
2.038e-02	-3.89	Rasd2 (RASD family, member 2)	protein interactions	75141	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Marcks (myristoylated alanine rich protein kinase C substrate)	protein interactions	17118	8	1	19454	50	PRKCA
2.038e-02	-3.89	CD163 (CD163 molecule)	protein interactions	9332	8	1	19454	50	PRKCA
2.038e-02	-3.89	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	1	19454	50	NTM
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.038e-02	-3.89	Prkca (protein kinase C, alpha)	protein interactions	24680	8	1	19454	50	PRKCA
2.038e-02	-3.89	BMP15 (bone morphogenetic protein 15)	protein interactions	9210	8	1	19454	50	BMPR1B
2.038e-02	-3.89	Rps27a (ribosomal protein S27A)	protein interactions	78294	8	1	19454	50	BMPR1B
2.049e-02	-3.89	Proteoglycans in cancer	KEGG pathways	ko05205	203	3	7161	21	ITPR2,PRKCA,HPSE2
2.049e-02	-3.89	Proteoglycans in cancer	KEGG pathways	hsa05205	203	3	7161	21	HPSE2,PRKCA,ITPR2
2.049e-02	-3.89	ACTIVIN2R	prints domains	PR00653	6	1	5227	18	BMPR1B
2.053e-02	-3.89	stress fiber	cellular component	GO:0001725	86	2	19108	49	NEBL,ABLIM1
2.053e-02	-3.89	contractile actin filament bundle	cellular component	GO:0097517	86	2	19108	49	ABLIM1,NEBL
2.058e-02	-3.88	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	5	16828	48	NTRK2,CTNND2,FBXL7,LIFR,ADCY2
2.067e-02	-3.88	lobular_carcinoma	COSMIC cancer mutations	lobular_carcinoma	763	6	16828	48	CDH20,TNIK,PRKCA,BMPR1B,FGFR3,NTRK2
2.067e-02	-3.88	breast-carcinoma-lobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-lobular_carcinoma	763	6	16828	48	NTRK2,FGFR3,BMPR1B,PRKCA,CDH20,TNIK
2.087e-02	-3.87	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	5	16828	48	CTNND2,NTRK2,ADCY2,FBXL7,LIFR
2.103e-02	-3.86	BMP receptor activity	molecular function	GO:0098821	8	1	18094	48	BMPR1B
2.103e-02	-3.86	sodium ion binding	molecular function	GO:0031402	8	1	18094	48	ATP1A2
2.103e-02	-3.86	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	48	ATP1A2
2.103e-02	-3.86	glutamate binding	molecular function	GO:0016595	8	1	18094	48	SLC1A3
2.108e-02	-3.86	NHLH1 (nescient helix-loop-helix 1)	protein interactions	4807	87	2	19454	50	NFIB,NFIA
2.108e-02	-3.86	MIR141 (microRNA 141)	protein interactions	406933	87	2	19454	50	QKI,MSI2
2.123e-02	-3.85	H1-5 (H1.5 linker histone, cluster member)	protein interactions	3009	412	4	19454	50	CSGALNACT1,MGAT4C,PARD3B,PRKCA
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	ATP1A2,NTRK2,TNIK
2.130e-02	-3.85	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	48	LIFR,FGFR3,NTRK2,TNIK,PRKCA
2.134e-02	-3.85	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	49	SLC1A3
2.134e-02	-3.85	dermatan sulfate proteoglycan biosynthetic process	biological process	GO:0050651	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	49	NRG3
2.134e-02	-3.85	type I pneumocyte differentiation	biological process	GO:0060509	8	1	18204	49	NFIB
2.134e-02	-3.85	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	49	ATP1A2
2.134e-02	-3.85	meiotic cytokinesis	biological process	GO:0033206	8	1	18204	49	FMN2
2.134e-02	-3.85	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological process	GO:0015014	8	1	18204	49	CSGALNACT1
2.134e-02	-3.85	mitotic nuclear membrane disassembly	biological process	GO:0007077	8	1	18204	49	PRKCA
2.140e-02	-3.84	AC_N	interpro domains	IPR032628	8	1	18521	50	ADCY2
2.140e-02	-3.84	Villin_headpiece_dom_sf	interpro domains	IPR036886	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Chond_GalNAc	interpro domains	IPR008428	8	1	18521	50	CSGALNACT1
2.140e-02	-3.84	Adcy	interpro domains	IPR030672	8	1	18521	50	ADCY2
2.140e-02	-3.84	Villin_headpiece	interpro domains	IPR003128	8	1	18521	50	ABLIM1
2.140e-02	-3.84	Plakin	interpro domains	IPR043197	8	1	18521	50	MACF1
2.147e-02	-3.84	cellular component organization or biogenesis	biological process	GO:0071840	5850	23	18204	49	MACF1,PARD3B,BMPR1B,HPSE2,TNIK,FMN2,NFIA,CSGALNACT1,PRKCA,PTPRZ1,PREX2,CTNND2,NFIB,SPARCL1,NRG3,AQP4,NEBL,CDH20,MAST4,GPM6A,PITPNC1,SLC1A2,ABLIM1
2.151e-02	-3.84	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	49	BMPR1B,CSGALNACT1
2.151e-02	-3.84	L-amino acid transport	biological process	GO:0015807	84	2	18204	49	SLC1A2,SLC1A3
2.151e-02	-3.84	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	49	NKAIN3,ATP1A2
2.153e-02	-3.84	RAP2A (RAP2A, member of RAS oncogene family)	protein interactions	5911	88	2	19454	50	TNIK,BMPR1B
2.153e-02	-3.84	Ig_sub	interpro domains	IPR003599	394	4	18521	50	NTRK2,LSAMP,NTM,FGFR3
2.158e-02	-3.84	HuR (ELAVL1) binds and stabilizes mRNA	REACTOME pathways	R-HSA-450520	8	1	10285	28	PRKCA
2.182e-02	-3.82	CHGN	pfam domains	PF05679	8	1	17795	49	CSGALNACT1
2.182e-02	-3.82	VHP	pfam domains	PF02209	8	1	17795	49	ABLIM1
2.182e-02	-3.82	AC_N	pfam domains	PF16214	8	1	17795	49	ADCY2
2.199e-02	-3.82	oligodendrocyte differentiation	biological process	GO:0048709	85	2	18204	49	NTRK2,PTPRZ1
2.199e-02	-3.82	SOX10 (SRY-box transcription factor 10)	protein interactions	6663	89	2	19454	50	NFIB,NFIA
2.201e-02	-3.82	organic anion transport	biological process	GO:0015711	398	4	18204	49	SFXN5,SLC1A2,NTRK2,SLC1A3
2.203e-02	-3.82	GAS2	smart domains	SM00243	6	1	9717	36	MACF1
2.203e-02	-3.82	EGFR tyrosine kinase inhibitor resistance	KEGG pathways	hsa01521	79	2	7161	21	PRKCA,FGFR3
2.203e-02	-3.82	EGFR tyrosine kinase inhibitor resistance	KEGG pathways	ko01521	79	2	7161	21	FGFR3,PRKCA
2.207e-02	-3.81	Endochondral Ossification	WikiPathways	WP474	65	2	5310	19	SOX5,FGFR3
2.237e-02	-3.80	forearm	COSMIC cancer mutations	forearm	81	2	16828	48	PREX2,FGFR3
2.240e-02	-3.80	Rap1 signaling pathway	KEGG pathways	ko04015	210	3	7161	21	FGFR3,ADCY2,PRKCA
2.240e-02	-3.80	Rap1 signaling pathway	KEGG pathways	hsa04015	210	3	7161	21	PRKCA,ADCY2,FGFR3
2.246e-02	-3.80	CTDSPL (CTD small phosphatase like)	protein interactions	10217	90	2	19454	50	FMN2,DTNA
2.247e-02	-3.80	central nervous system neuron development	biological process	GO:0021954	86	2	18204	49	NTRK2,NFIB
2.249e-02	-3.79	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	3	19454	50	MACF1,DTNA,NTRK2
2.260e-02	-3.79	trichoblastoma	COSMIC cancer mutations	trichoblastoma	8	1	16828	48	FGFR3
2.260e-02	-3.79	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-ureter-carcinoma-transitional_cell_carcinoma	8	1	16828	48	FGFR3
2.260e-02	-3.79	cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	48	FGFR3
2.260e-02	-3.79	junctional	COSMIC cancer mutations	junctional	8	1	16828	48	FGFR3
2.260e-02	-3.79	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	48	QKI
2.260e-02	-3.79	actinic_keratosis	COSMIC cancer mutations	actinic_keratosis	8	1	16828	48	FGFR3
2.260e-02	-3.79	skin-chest-malignant_melanoma-nodular	COSMIC cancer mutations	skin-chest-malignant_melanoma-nodular	8	1	16828	48	PREX2
2.260e-02	-3.79	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I	8	1	16828	48	FGFR3
2.264e-02	-3.79	LIM_DOMAIN_2	prosite domains	PS50023	71	2	12186	40	ABLIM1,NEBL
2.264e-02	-3.79	LIM_DOMAIN_1	prosite domains	PS00478	71	2	12186	40	NEBL,ABLIM1
2.271e-02	-3.79	Oncostatin M Signaling Pathway	WikiPathways	WP2374	66	2	5310	19	PRKCA,LIFR
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.276e-02	-3.78	HEMATOPO_REC_L_F2	prosite domains	PS01353	7	1	12186	40	LIFR
2.276e-02	-3.78	GS	prosite domains	PS51256	7	1	12186	40	BMPR1B
2.278e-02	-3.78	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour	213	3	16828	48	PCDH9,FMN2,FGFR3
2.278e-02	-3.78	atypical_teratoid-rhabdoid_tumour	COSMIC cancer mutations	atypical_teratoid-rhabdoid_tumour	213	3	16828	48	PCDH9,FGFR3,FMN2
2.285e-02	-3.78	astrocyte end-foot	cellular component	GO:0097450	9	1	19108	49	AQP4
2.285e-02	-3.78	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	49	ITPR2
2.290e-02	-3.78	VEPH1 (ventricular zone expressed PH domain containing 1)	protein interactions	79674	9	1	19454	50	BMPR1B
2.290e-02	-3.78	NRXN2 (neurexin 2)	protein interactions	9379	9	1	19454	50	MACF1
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	FGFR3
2.290e-02	-3.78	GUSBP1 (GUSB pseudogene 1)	protein interactions	728411	9	1	19454	50	FGFR3
2.290e-02	-3.78	BIN2 (bridging integrator 2)	protein interactions	51411	9	1	19454	50	EFEMP1
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	SCTR (secretin receptor)	protein interactions	6344	9	1	19454	50	PRKCA
2.290e-02	-3.78	ZNF778 (zinc finger protein 778)	protein interactions	197320	9	1	19454	50	EFEMP1
2.292e-02	-3.78	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	2	19454	50	GPM6A,NTM
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	SOX5,GPM6A,ITPR2
2.299e-02	-3.77	Villin headpiece domain	gene3d domains	1.10.950.10	8	1	14470	42	ABLIM1
2.319e-02	-3.76	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	REACTOME pathways	R-HSA-6811558	87	2	10285	28	NRG3,FGFR3
2.320e-02	-3.76	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	SMPDB pathways	SMP0000354	8	1	1369	4	ADCY2
2.320e-02	-3.76	Bile Acid Indirect Signalling Pathway	SMPDB pathways	SMP0086851	8	1	1369	4	FGFR3
2.329e-02	-3.76	actomyosin	cellular component	GO:0042641	92	2	19108	49	ABLIM1,NEBL
2.339e-02	-3.76	POTEI (POTE ankyrin domain family member I)	protein interactions	653269	92	2	19454	50	DTNA,FGFR3
2.339e-02	-3.76	FNTA (farnesyltransferase, CAAX box, subunit alpha)	protein interactions	2339	92	2	19454	50	FGFR3,TNIK
2.339e-02	-3.76	DPF1 (double PHD fingers 1)	protein interactions	8193	92	2	19454	50	NFIA,NFIB
2.363e-02	-3.75	calcium-dependent protein serine/threonine kinase activity	molecular function	GO:0009931	9	1	18094	48	PRKCA
2.369e-02	-3.74	Signaling by the B Cell Receptor (BCR)	REACTOME pathways	R-HSA-983705	229	3	10285	28	NRG3,ITPR2,FGFR3
2.387e-02	-3.74	TEX11 (testis expressed 11)	protein interactions	56159	93	2	19454	50	SOX5,QKI
2.387e-02	-3.74	MIR19B2 (microRNA 19b-2)	protein interactions	406981	93	2	19454	50	MSI2,QKI
2.387e-02	-3.74	DMRTB1 (DMRT like family B with proline rich C-terminal 1)	protein interactions	63948	93	2	19454	50	QKI,MSI2
2.387e-02	-3.74	ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	protein interactions	9459	93	2	19454	50	ABLIM1,BMPR1B
2.387e-02	-3.74	parotid	COSMIC cancer mutations	parotid	578	5	16828	48	NTRK2,FGFR3,LIFR,PRKCA,TNIK
2.391e-02	-3.73	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	3	16828	48	MGAT4C,PON2,DTNA
2.395e-02	-3.73	cell fate specification	biological process	GO:0001708	89	2	18204	49	NFIB,NFIA
2.397e-02	-3.73	polyamine transmembrane transport	biological process	GO:1902047	9	1	18204	49	ATP13A4
2.397e-02	-3.73	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	49	ATP1A2
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.404e-02	-3.73	Activin_recp	interpro domains	IPR000472	9	1	18521	50	BMPR1B
2.404e-02	-3.73	Peptidase_S9	interpro domains	IPR001375	9	1	18521	50	DPP10
2.411e-02	-3.73	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	49	FGFR3,PREX2,ITPR2,ADCY2,ATP1A2,TNIK
2.420e-02	-3.72	ACTG1 (actin gamma 1)	protein interactions	71	429	4	19454	50	ABLIM1,TNIK,FMN2,PRKCA
2.425e-02	-3.72	EGFR Transactivation by Gastrin	REACTOME pathways	R-HSA-2179392	9	1	10285	28	PRKCA
2.425e-02	-3.72	Synthesis of 5-eicosatetraenoic acids	REACTOME pathways	R-HSA-2142688	9	1	10285	28	PON2
2.435e-02	-3.72	QSER1 (glutamine and serine rich 1)	protein interactions	79832	94	2	19454	50	SOX5,NFIA
2.438e-02	-3.71	postsynapse	cellular component	GO:0098794	646	5	19108	49	NTRK2,CTNND2,GPM6A,ATP1A2,TNIK
2.450e-02	-3.71	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	48	PREX2,ITPR2,PARD3B,FMN2,FGFR3
2.452e-02	-3.71	Peptidase_S9	pfam domains	PF00326	9	1	17795	49	DPP10
2.452e-02	-3.71	Activin_recp	pfam domains	PF01064	9	1	17795	49	BMPR1B
2.459e-02	-3.71	human chr5p15.1	chromosome location	human chr5p15.1	13	1	26134	50	FBXL7
2.470e-02	-3.70	PI3K/AKT Signaling in Cancer	REACTOME pathways	R-HSA-2219528	90	2	10285	28	FGFR3,NRG3
2.489e-02	-3.69	adenyl nucleotide binding	molecular function	GO:0030554	1620	9	18094	48	MAST4,FGFR3,TNIK,ATP1A2,BMPR1B,PRKCA,ATP13A4,NTRK2,ADCY2
2.496e-02	-3.69	response to BMP	biological process	GO:0071772	91	2	18204	49	NFIA,BMPR1B
2.496e-02	-3.69	cellular response to BMP stimulus	biological process	GO:0071773	91	2	18204	49	NFIA,BMPR1B
2.521e-02	-3.68	actin filament bundle	cellular component	GO:0032432	96	2	19108	49	NEBL,ABLIM1
2.526e-02	-3.68	ErbB signaling pathway	KEGG pathways	hsa04012	85	2	7161	21	PRKCA,NRG3
2.526e-02	-3.68	ErbB signaling pathway	KEGG pathways	ko04012	85	2	7161	21	NRG3,PRKCA
2.532e-02	-3.68	RLIM (ring finger protein, LIM domain interacting)	protein interactions	51132	96	2	19454	50	NFIA,NFIB
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.539e-02	-3.67	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	48	FGFR3
2.539e-02	-3.67	compound	COSMIC cancer mutations	compound	9	1	16828	48	FGFR3
2.539e-02	-3.67	in_situ_epithelial_neoplasm	COSMIC cancer mutations	in_situ_epithelial_neoplasm	9	1	16828	48	FGFR3
2.539e-02	-3.67	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	48	PREX2
2.539e-02	-3.67	skin-upper_leg-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma-superficial_spreading	9	1	16828	48	PREX2
2.539e-02	-3.67	epidermal_nevus	COSMIC cancer mutations	epidermal_nevus	9	1	16828	48	FGFR3
2.539e-02	-3.67	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	COSMIC cancer mutations	ovary-low_malignant_potential_(borderline)_tumour-Brenner_tumour	9	1	16828	48	FGFR3
2.539e-02	-3.67	Bowen_disease	COSMIC cancer mutations	Bowen_disease	9	1	16828	48	FGFR3
2.539e-02	-3.67	skin-other-seborrhoeic_keratosis	COSMIC cancer mutations	skin-other-seborrhoeic_keratosis	9	1	16828	48	FGFR3
2.541e-02	-3.67	PPY (pancreatic polypeptide)	protein interactions	5539	10	1	19454	50	PRKCA
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	ALKAL2 (ALK and LTK ligand 2)	protein interactions	285016	10	1	19454	50	PON2
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	GSG1 (germ cell associated 1)	protein interactions	83445	10	1	19454	50	PITPNC1
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.541e-02	-3.67	TNP1 (transition protein 1)	protein interactions	7141	10	1	19454	50	PRKCA
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	Vbp1 (von Hippel-Lindau binding protein 1)	protein interactions	22327	10	1	19454	50	ABLIM1
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.547e-02	-3.67	YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)	protein interactions	7534	1138	7	19454	50	PRKCA,MAST4,NHSL1,MACF1,PARD3B,PITPNC1,ABLIM1
2.551e-02	-3.67	CCDC8 (coiled-coil domain containing 8)	protein interactions	83987	652	5	19454	50	ABLIM1,NTRK2,ITPR2,MACF1,PRKCA
2.566e-02	-3.66	PLEC	smart domains	SM00250	7	1	9717	36	MACF1
2.566e-02	-3.66	GS	smart domains	SM00467	7	1	9717	36	BMPR1B
2.573e-02	-3.66	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	28	LSAMP,NTM
2.597e-02	-3.65	HP	prosite domains	PS51089	8	1	12186	40	ABLIM1
2.607e-02	-3.65	Nitric Oxide Signaling Pathway	SMPDB pathways	SMP0063777	9	1	1369	4	PRKCA
2.607e-02	-3.65	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	SMPDB pathways	SMP0000333	9	1	1369	4	ADCY2
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB pathways	SMP0000312	9	1	1369	4	ADCY2
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB pathways	SMP0000309	9	1	1369	4	ADCY2
2.607e-02	-3.65	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB pathways	SMP0000335	9	1	1369	4	ADCY2
2.607e-02	-3.65	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB pathways	SMP0000311	9	1	1369	4	ADCY2
2.610e-02	-3.65	Heparan sulfate degradation	KEGG pathways	hsa_M00078	9	1	7161	21	HPSE2
2.610e-02	-3.65	Heparan sulfate degradation	KEGG pathways	M00078	9	1	7161	21	HPSE2
2.616e-02	-3.64	protein localization to cell periphery	biological process	GO:1990778	238	3	18204	49	TNIK,MACF1,DPP10
2.622e-02	-3.64	phosphatidylinositol transfer activity	molecular function	GO:0008526	10	1	18094	48	PITPNC1
2.622e-02	-3.64	neurotrophin binding	molecular function	GO:0043121	10	1	18094	48	NTRK2
2.622e-02	-3.64	polyamine transmembrane transporter activity	molecular function	GO:0015203	10	1	18094	48	ATP13A4
2.622e-02	-3.64	calcium-dependent protein kinase activity	molecular function	GO:0010857	10	1	18094	48	PRKCA
2.625e-02	-3.64	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	3	16828	48	DTNA,PON2,MGAT4C
2.625e-02	-3.64	cell surface	cellular component	GO:0009986	896	6	19108	49	SLC1A3,AQP4,ATP1A2,FGFR3,LIFR,SLC1A2
2.631e-02	-3.64	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	50	QKI,SOX5
2.631e-02	-3.64	FRS2 (fibroblast growth factor receptor substrate 2)	protein interactions	10818	98	2	19454	50	NTRK2,FGFR3
2.631e-02	-3.64	FRAS1 (Fraser extracellular matrix complex subunit 1)	protein interactions	80144	98	2	19454	50	MGAT4C,HPSE2
2.631e-02	-3.64	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	2	19454	50	LSAMP,GPM6A
2.645e-02	-3.63	dermatan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6571	12	1	902	2	CSGALNACT1
2.646e-02	-3.63	human chr2p13.2	chromosome location	human chr2p13.2	14	1	26134	50	SFXN5
2.651e-02	-3.63	protein serine/threonine kinase activity	molecular function	GO:0004674	428	4	18094	48	TNIK,BMPR1B,MAST4,PRKCA
2.660e-02	-3.63	desmosome organization	biological process	GO:0002934	10	1	18204	49	PRKCA
2.660e-02	-3.63	positive regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031666	10	1	18204	49	PRKCA
2.660e-02	-3.63	establishment of centrosome localization	biological process	GO:0051660	10	1	18204	49	PARD3B
2.660e-02	-3.63	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	49	SOX5
2.660e-02	-3.63	negative regulation of glial cell apoptotic process	biological process	GO:0034351	10	1	18204	49	PRKCA
2.660e-02	-3.63	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	49	NRG3
2.660e-02	-3.63	retinal rod cell development	biological process	GO:0046548	10	1	18204	49	NTRK2
2.660e-02	-3.63	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	49	NRG3
2.660e-02	-3.63	cAMP biosynthetic process	biological process	GO:0006171	10	1	18204	49	ADCY2
2.660e-02	-3.63	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	1	18204	49	NTRK2
2.660e-02	-3.63	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	49	NTRK2
2.660e-02	-3.63	lung secretory cell differentiation	biological process	GO:0061140	10	1	18204	49	NFIB
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	ITPR2
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	ITPR2
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.678e-02	-3.62	Negative regulation of the PI3K/AKT network	REACTOME pathways	R-HSA-199418	94	2	10285	28	NRG3,FGFR3
2.680e-02	-3.62	TNKS (tankyrase)	protein interactions	8658	99	2	19454	50	TNIK,PCDH9
2.683e-02	-3.62	ATPase-coupled transmembrane transporter activity	molecular function	GO:0042626	96	2	18094	48	ATP1A2,ATP13A4
2.686e-02	-3.62	cellular response to stimulus	biological process	GO:0051716	6307	24	18204	49	MAST4,ZBTB20,SLC1A2,EFEMP1,LIFR,FGFR3,CTNND2,PREX2,AQP4,NRG3,TNIK,PRKCA,NTRK2,PITPNC1,ATP1A2,DTNA,SPARCL1,BMPR1B,FMN2,NFIA,ITPR2,ADCY2,MACF1,SLC1A3
2.690e-02	-3.62	Signaling by FGFR3 fusions in cancer	REACTOME pathways	R-HSA-8853334	10	1	10285	28	FGFR3
2.690e-02	-3.62	Adenylate cyclase activating pathway	REACTOME pathways	R-HSA-170660	10	1	10285	28	ADCY2
2.690e-02	-3.62	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	28	NRG3
2.690e-02	-3.62	Acetylcholine regulates insulin secretion	REACTOME pathways	R-HSA-399997	10	1	10285	28	PRKCA
2.693e-02	-3.61	NCK2 (NCK adaptor protein 2)	protein interactions	8440	252	3	19454	50	NTRK2,TNIK,NHSL1
2.695e-02	-3.61	GABAergic synapse	KEGG pathways	hsa04727	88	2	7161	21	ADCY2,PRKCA
2.695e-02	-3.61	GABAergic synapse	KEGG pathways	ko04727	88	2	7161	21	ADCY2,PRKCA
2.701e-02	-3.61	anchoring junction	cellular component	GO:0070161	902	6	19108	49	PCDH9,ATP1A2,CTNND2,PARD3B,CDH20,FGFR3
2.719e-02	-3.61	extrinsic component of plasma membrane	cellular component	GO:0019897	100	2	19108	49	DTNA,CDH20
2.719e-02	-3.60	Tyr_kinase_AS	interpro domains	IPR008266	95	2	18521	50	FGFR3,NTRK2
2.720e-02	-3.60	PAS_3	pfam domains	PF08447	10	1	17795	49	NPAS3
2.720e-02	-3.60	MIR	pfam domains	PF02815	10	1	17795	49	ITPR2
2.731e-02	-3.60	MIDEAS (mitotic deacetylase associated SANT domain protein)	protein interactions	91748	100	2	19454	50	NFIB,NFIA
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	GPM6A,ATP1A2
2.758e-02	-3.59	monoatomic cation transmembrane transport	biological process	GO:0098655	636	5	18204	49	GPM6A,ATP13A4,ITPR2,ATP1A2,SLC1A3
2.771e-02	-3.59	actin binding	molecular function	GO:0003779	434	4	18094	48	FMN2,MACF1,NEBL,ABLIM1
2.780e-02	-3.58	cell surface receptor protein tyrosine kinase signaling pathway	biological process	GO:0007169	428	4	18204	49	EFEMP1,FGFR3,NTRK2,NRG3
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.786e-02	-3.58	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	49	ITPR2
2.792e-02	-3.58	ITPKA (inositol-trisphosphate 3-kinase A)	protein interactions	3706	11	1	19454	50	PRKCA
2.792e-02	-3.58	Batf3 (basic leucine zipper transcription factor, ATF-like 3)	protein interactions	381319	11	1	19454	50	MACF1
2.792e-02	-3.58	Cobll1 (Cobl-like 1)	protein interactions	319876	11	1	19454	50	ABLIM1
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	ITPR2
2.792e-02	-3.58	TMEM53 (transmembrane protein 53)	protein interactions	79639	11	1	19454	50	PRKCA
2.792e-02	-3.58	Wipi2 (WD repeat domain, phosphoinositide interacting 2)	protein interactions	74781	11	1	19454	50	MACF1
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	CCDC17 (coiled-coil domain containing 17)	protein interactions	149483	11	1	19454	50	FGFR3
2.792e-02	-3.58	Gtf2e2 (general transcription factor II E, polypeptide 2 (beta subunit))	protein interactions	68153	11	1	19454	50	NHSL1
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.810e-02	-3.57	amino acid transmembrane transport	biological process	GO:0003333	97	2	18204	49	SLC1A2,SLC1A3
2.817e-02	-3.57	lung-carcinoma-pleomorphic_carcinoma	COSMIC cancer mutations	lung-carcinoma-pleomorphic_carcinoma	10	1	16828	48	FGFR3
2.817e-02	-3.57	renal_cell_carcinoma_unclassified	COSMIC cancer mutations	renal_cell_carcinoma_unclassified	10	1	16828	48	FGFR3
2.817e-02	-3.57	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	48	PREX2
2.817e-02	-3.57	kidney-carcinoma-renal_cell_carcinoma_unclassified	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma_unclassified	10	1	16828	48	FGFR3
2.817e-02	-3.57	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	48	FGFR3
2.817e-02	-3.57	cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	48	FGFR3
2.817e-02	-3.57	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	COSMIC cancer mutations	cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III	10	1	16828	48	FGFR3
2.817e-02	-3.57	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	48	QKI
2.826e-02	-3.57	LIM	smart domains	SM00132	71	2	9717	36	NEBL,ABLIM1
2.829e-02	-3.57	Phase I biotransformations, non P450	WikiPathways	WP136	8	1	5310	19	PON2
2.832e-02	-3.56	human chr8q12.3	chromosome location	human chr8q12.3	15	1	26134	50	NKAIN3
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	NEBL
2.832e-02	-3.56	MIR7-1 (microRNA 7-1)	protein interactions	407043	102	2	19454	50	MSI2,QKI
2.832e-02	-3.56	KRTAP6-1 (keratin associated protein 6-1)	protein interactions	337966	102	2	19454	50	GLIS3,EFEMP1
2.842e-02	-3.56	trans-synaptic signaling	biological process	GO:0099537	431	4	18204	49	DTNA,SLC1A2,SLC1A3,NTRK2
2.860e-02	-3.55	PLCG1 (phospholipase C gamma 1)	protein interactions	5335	258	3	19454	50	FGFR3,LIFR,NTRK2
2.868e-02	-3.55	Morphine addiction	KEGG pathways	ko05032	91	2	7161	21	ADCY2,PRKCA
2.868e-02	-3.55	Morphine addiction	KEGG pathways	hsa05032	91	2	7161	21	ADCY2,PRKCA
2.880e-02	-3.55	histone H3 kinase activity	molecular function	GO:0140996	11	1	18094	48	PRKCA
2.880e-02	-3.55	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	48	SLC1A2
2.884e-02	-3.55	CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2)	protein interactions	55454	103	2	19454	50	MGAT4C,CSGALNACT1
2.884e-02	-3.55	RAB6B (RAB6B, member RAS oncogene family)	protein interactions	51560	103	2	19454	50	GPM6A,BMPR1B
2.893e-02	-3.54	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	2	18094	48	SLC1A3,SLC1A2
2.893e-02	-3.54	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	SMPDB pathways	SMP0000338	10	1	1369	4	ADCY2
2.894e-02	-3.54	Ig-like_dom	interpro domains	IPR007110	432	4	18521	50	NTM,FGFR3,NTRK2,LSAMP
2.922e-02	-3.53	glutamate secretion	biological process	GO:0014047	11	1	18204	49	NTRK2
2.922e-02	-3.53	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	49	ATP1A2
2.922e-02	-3.53	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	49	QKI
2.922e-02	-3.53	ectodermal placode formation	biological process	GO:0060788	11	1	18204	49	NRG3
2.922e-02	-3.53	polyamine transport	biological process	GO:0015846	11	1	18204	49	ATP13A4
2.922e-02	-3.53	antral ovarian follicle growth	biological process	GO:0001547	11	1	18204	49	BMPR1B
2.922e-02	-3.53	heparin biosynthetic process	biological process	GO:0030210	11	1	18204	49	CSGALNACT1
2.922e-02	-3.53	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	49	ATP1A2
2.922e-02	-3.53	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	49	NRG3
2.922e-02	-3.53	lactone metabolic process	biological process	GO:1901334	11	1	18204	49	ATP1A2
2.922e-02	-3.53	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	49	NRG3
2.927e-02	-3.53	VHP	smart domains	SM00153	8	1	9717	36	ABLIM1
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	SPARCL1,ABLIM1
2.946e-02	-3.52	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	3	19454	50	MACF1,FMN2,DTNA
2.972e-02	-3.52	response to alkaloid	biological process	GO:0043279	100	2	18204	49	SLC1A3,SLC1A2
2.979e-02	-3.51	active transmembrane transporter activity	molecular function	GO:0022804	444	4	18094	48	SLC1A3,ATP1A2,SLC1A2,ATP13A4
2.988e-02	-3.51	IRF2BP2 (interferon regulatory factor 2 binding protein 2)	protein interactions	359948	105	2	19454	50	NFIA,NFIB
2.988e-02	-3.51	ABCA2 (ATP binding cassette subfamily A member 2)	protein interactions	20	105	2	19454	50	FGFR3,PON2
3.033e-02	-3.50	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	48	ATP1A2,ZBTB20,PRKCA,NPAS3,NTM,DPP10,PARD3B,MACF1
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.036e-02	-3.49	NRAS (NRAS proto-oncogene, GTPase)	protein interactions	4893	683	5	19454	50	MACF1,PCDH9,FMN2,SLC1A3,TNIK
3.040e-02	-3.49	ARID3B (AT-rich interaction domain 3B)	protein interactions	10620	106	2	19454	50	NFIA,NFIB
3.040e-02	-3.49	USP30 (ubiquitin specific peptidase 30)	protein interactions	84749	106	2	19454	50	QKI,FGFR3
3.042e-02	-3.49	Ctnnbl1 (catenin, beta like 1)	protein interactions	66642	12	1	19454	50	PRKCA
3.042e-02	-3.49	NKX2-4 (NK2 homeobox 4)	protein interactions	644524	12	1	19454	50	NFIB
3.042e-02	-3.49	CTF1 (cardiotrophin 1)	protein interactions	1489	12	1	19454	50	LIFR
3.042e-02	-3.49	UGT1A9 (UDP glucuronosyltransferase family 1 member A9)	protein interactions	54600	12	1	19454	50	PON2
3.042e-02	-3.49	XK (X-linked Kx blood group antigen, Kell and VPS13A binding protein)	protein interactions	7504	12	1	19454	50	PRKCA
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.042e-02	-3.49	BAMBI (BMP and activin membrane bound inhibitor)	protein interactions	25805	12	1	19454	50	BMPR1B
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.054e-02	-3.49	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	43	16828	48	NRG3,ATP13A4,AQP4,SOX5,MACF1,PTPRZ1,GLIS3,NTRK2,TNIK,NFIB,PARD3B,ATP1A2,NEBL,LIFR,NTM,CDH20,PON2,QKI,FMN2,CSGALNACT1,PRKCA,SLC1A3,GPM6A,ITPR2,NKAIN3,ZBTB20,PREX2,EFEMP1,SFXN5,DPP10,CTNND2,NHSL1,SLC1A2,FBXL7,FGFR3,SPARCL1,ADCY2,LSAMP,PCDH9,NPAS3,BMPR1B,MGAT4C,HPSE2
3.058e-02	-3.49	CTNNB1 (catenin beta 1)	protein interactions	1499	926	6	19454	50	PTPRZ1,CTNND2,NHSL1,PRKCA,DTNA,PARD3B
3.065e-02	-3.49	Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME pathways	R-HSA-881907	443	4	10285	28	FGFR3,ITPR2,PRKCA,NRG3
3.083e-02	-3.48	response to stimulus	biological process	GO:0050896	7803	28	18204	49	ADCY2,ITPR2,SLC1A3,MACF1,FMN2,BMPR1B,NFIA,DTNA,SPARCL1,GPM6A,ATP1A2,PITPNC1,TNIK,NTRK2,PRKCA,SOX5,NRG3,AQP4,PREX2,FGFR3,CTNND2,NFIB,LIFR,ZBTB20,PON2,MAST4,EFEMP1,SLC1A2
3.093e-02	-3.48	APLP2 (amyloid beta precursor like protein 2)	protein interactions	334	107	2	19454	50	HPSE2,PRKCA
3.094e-02	-3.48	oncocytoma	COSMIC cancer mutations	oncocytoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	congenital	COSMIC cancer mutations	congenital	11	1	16828	48	FGFR3
3.094e-02	-3.48	skin-scalp-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-basal_cell_carcinoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	48	PREX2
3.094e-02	-3.48	kidney-other-oncocytoma	COSMIC cancer mutations	kidney-other-oncocytoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	prostate-hyperplasia	COSMIC cancer mutations	prostate-hyperplasia	11	1	16828	48	FGFR3
3.094e-02	-3.48	pleomorphic_carcinoma	COSMIC cancer mutations	pleomorphic_carcinoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	skin-neck-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-neck-carcinoma-basal_cell_carcinoma	11	1	16828	48	FGFR3
3.094e-02	-3.48	seborrhoeic_keratosis	COSMIC cancer mutations	seborrhoeic_keratosis	11	1	16828	48	FGFR3
3.094e-02	-3.48	skin-hand-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-hand-malignant_melanoma-acral_lentiginous	11	1	16828	48	PREX2
3.100e-02	-3.47	RHOA (ras homolog family member A)	protein interactions	387	1186	7	19454	50	PARD3B,MACF1,ITPR2,PRKCA,PON2,FMN2,PREX2
3.101e-02	-3.47	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	18	16828	48	CTNND2,NFIA,TNIK,PCDH9,FGFR3,ITPR2,MACF1,SOX5,ADCY2,LIFR,ATP13A4,ATP1A2,DTNA,AQP4,SPARCL1,LSAMP,GLIS3,PTPRZ1
3.138e-02	-3.46	dipeptidyl-peptidase activity	molecular function	GO:0008239	12	1	18094	48	DPP10
3.138e-02	-3.46	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	48	ADCY2
3.138e-02	-3.46	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	48	ITPR2
3.147e-02	-3.46	DSG4 (desmoglein 4)	protein interactions	147409	108	2	19454	50	CSGALNACT1,SPARCL1
3.147e-02	-3.46	EN1 (engrailed homeobox 1)	protein interactions	2019	108	2	19454	50	NFIB,NFIA
3.147e-02	-3.46	PAX8 (paired box 8)	protein interactions	7849	108	2	19454	50	NFIB,NFIA
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	FMN2,MACF1,NHSL1,ABLIM1
3.151e-02	-3.46	VCL (vinculin)	protein interactions	7414	268	3	19454	50	MACF1,PRKCA,NEBL
3.166e-02	-3.45	Circadian entrainment	KEGG pathways	ko04713	96	2	7161	21	PRKCA,ADCY2
3.166e-02	-3.45	Circadian entrainment	KEGG pathways	hsa04713	96	2	7161	21	ADCY2,PRKCA
3.182e-02	-3.45	cell fate commitment	biological process	GO:0045165	257	3	18204	49	NFIB,NFIA,SOX5
3.184e-02	-3.45	auditory behavior	biological process	GO:0031223	12	1	18204	49	SLC1A3
3.184e-02	-3.45	regulation of glial cell apoptotic process	biological process	GO:0034350	12	1	18204	49	PRKCA
3.184e-02	-3.45	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological process	GO:1902043	12	1	18204	49	BMPR1B
3.184e-02	-3.45	dermatan sulfate proteoglycan metabolic process	biological process	GO:0050655	12	1	18204	49	CSGALNACT1
3.184e-02	-3.45	nuclear membrane disassembly	biological process	GO:0051081	12	1	18204	49	PRKCA
3.184e-02	-3.45	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	49	SLC1A2
3.184e-02	-3.45	microglia differentiation	biological process	GO:0014004	12	1	18204	49	QKI
3.184e-02	-3.45	mammalian oogenesis stage	biological process	GO:0022605	12	1	18204	49	BMPR1B
3.193e-02	-3.44	TGFB_receptor	interpro domains	IPR000333	12	1	18521	50	BMPR1B
3.200e-02	-3.44	CLSTN1 (calsyntenin 1)	protein interactions	22883	109	2	19454	50	SLC1A3,MGAT4C
3.200e-02	-3.44	MIR34B (microRNA 34b)	protein interactions	407041	109	2	19454	50	QKI,MSI2
3.200e-02	-3.44	ZNRF4 (zinc and ring finger 4)	protein interactions	148066	109	2	19454	50	PON2,ITPR2
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.220e-02	-3.44	Signaling by activated point mutants of FGFR3	REACTOME pathways	R-HSA-1839130	12	1	10285	28	FGFR3
3.220e-02	-3.44	FGFR3 mutant receptor activation	REACTOME pathways	R-HSA-2033514	12	1	10285	28	FGFR3
3.226e-02	-3.43	Phosphatidylinositol signaling system	KEGG pathways	ko04070	97	2	7161	21	ITPR2,PRKCA
3.226e-02	-3.43	Phosphatidylinositol signaling system	KEGG pathways	hsa04070	97	2	7161	21	PRKCA,ITPR2
3.236e-02	-3.43	MIR	prosite domains	PS50919	10	1	12186	40	ITPR2
3.236e-02	-3.43	MIP	prosite domains	PS00221	10	1	12186	40	AQP4
3.240e-02	-3.43	EF-hand-dom_pair	interpro domains	IPR011992	258	3	18521	50	SPARCL1,DTNA,MACF1
3.243e-02	-3.43	large_intestine-rectum-adenoma	COSMIC cancer mutations	large_intestine-rectum-adenoma	99	2	16828	48	NTRK2,LIFR
3.246e-02	-3.43	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	45	16828	48	CSGALNACT1,QKI,FMN2,NFIA,PRKCA,SLC1A3,NTM,LIFR,ATP1A2,NEBL,PON2,CDH20,TNIK,NFIB,PARD3B,MACF1,SOX5,PITPNC1,ATP13A4,NRG3,NTRK2,GLIS3,PTPRZ1,BMPR1B,NPAS3,PCDH9,HPSE2,MGAT4C,ADCY2,ABLIM1,DTNA,SPARCL1,LSAMP,CTNND2,DPP10,MSI2,SFXN5,FGFR3,FBXL7,SLC1A2,ITPR2,GPM6A,ZBTB20,EFEMP1,PREX2
3.251e-02	-3.43	cellular response to alcohol	biological process	GO:0097306	105	2	18204	49	ADCY2,ITPR2
3.251e-02	-3.43	gland morphogenesis	biological process	GO:0022612	105	2	18204	49	NFIB,NRG3
3.254e-02	-3.43	LZTR1 (leucine zipper like post translational regulator 1)	protein interactions	8216	110	2	19454	50	BMPR1B,PARD3B
3.276e-02	-3.42	beta-catenin binding	molecular function	GO:0008013	107	2	18094	48	CDH20,CTNND2
3.281e-02	-3.42	distal axon	cellular component	GO:0150034	273	3	19108	49	GPM6A,PCDH9,NTRK2
3.287e-02	-3.42	FOLN	smart domains	SM00274	9	1	9717	36	SPARCL1
3.288e-02	-3.41	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	21	ITPR2,ADCY2
3.288e-02	-3.41	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	21	ITPR2,ADCY2
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.291e-02	-3.41	PCDHA2 (protocadherin alpha 2)	protein interactions	56146	13	1	19454	50	NFIA
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	DDIAS (DNA damage induced apoptosis suppressor)	protein interactions	220042	13	1	19454	50	EFEMP1
3.291e-02	-3.41	SPINK5 (serine peptidase inhibitor Kazal type 5)	protein interactions	11005	13	1	19454	50	CSGALNACT1
3.291e-02	-3.41	ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)	protein interactions	8869	13	1	19454	50	PON2
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	IL23R (interleukin 23 receptor)	protein interactions	149233	13	1	19454	50	PRKCA
3.291e-02	-3.41	KCNQ2 (potassium voltage-gated channel subfamily Q member 2)	protein interactions	3785	13	1	19454	50	PRKCA
3.300e-02	-3.41	dermatan sulfate biosynthesis	BIOCYC pathways	META_PWY-6571	15	1	902	2	CSGALNACT1
3.302e-02	-3.41	FHL3 (four and a half LIM domains 3)	protein interactions	2275	273	3	19454	50	QKI,NEBL,FGFR3
3.307e-02	-3.41	oogenesis	biological process	GO:0048477	106	2	18204	49	BMPR1B,FMN2
3.309e-02	-3.41	BCL7C (BAF chromatin remodeling complex subunit BCL7C)	protein interactions	9274	111	2	19454	50	NFIA,NFIB
3.309e-02	-3.41	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	3	18204	49	PCDH9,CDH20,SPARCL1
3.371e-02	-3.39	cervix-carcinoma-mixed_adenosquamous_carcinoma	COSMIC cancer mutations	cervix-carcinoma-mixed_adenosquamous_carcinoma	12	1	16828	48	FGFR3
3.371e-02	-3.39	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	48	QKI
3.371e-02	-3.39	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	48	FGFR3
3.371e-02	-3.39	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	48	PREX2
3.371e-02	-3.39	skin-face-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-basal_cell_carcinoma	12	1	16828	48	FGFR3
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.389e-02	-3.38	human chr18q21.33	chromosome location	human chr18q21.33	18	1	26134	50	CDH20
3.395e-02	-3.38	potassium ion binding	molecular function	GO:0030955	13	1	18094	48	ATP1A2
3.395e-02	-3.38	transforming growth factor beta receptor activity	molecular function	GO:0005024	13	1	18094	48	BMPR1B
3.396e-02	-3.38	regulation of nervous system development	biological process	GO:0051960	456	4	18204	49	NTRK2,MACF1,PTPRZ1,QKI
3.400e-02	-3.38	calcium ion binding	molecular function	GO:0005509	683	5	18094	48	EFEMP1,SPARCL1,PCDH9,ITPR2,MACF1
3.400e-02	-3.38	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	28	SLC1A2,SLC1A3
3.408e-02	-3.38	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	3	18094	48	SFXN5,SLC1A3,SLC1A2
3.418e-02	-3.38	GFI1B (growth factor independent 1B transcriptional repressor)	protein interactions	8328	113	2	19454	50	EFEMP1,DTNA
3.425e-02	-3.37	ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)	protein interactions	23390	277	3	19454	50	GPM6A,NEBL,SLC1A3
3.425e-02	-3.37	ACIN1 (apoptotic chromatin condensation inducer 1)	protein interactions	22985	277	3	19454	50	PRKCA,CSGALNACT1,NFIA
3.444e-02	-3.37	commissural neuron axon guidance	biological process	GO:0071679	13	1	18204	49	NFIB
3.444e-02	-3.37	ectodermal placode development	biological process	GO:0071696	13	1	18204	49	NRG3
3.444e-02	-3.37	membrane disassembly	biological process	GO:0030397	13	1	18204	49	PRKCA
3.444e-02	-3.37	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	49	ATP1A2
3.444e-02	-3.37	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	49	ATP1A2
3.464e-02	-3.36	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	4	ATP1A2
3.464e-02	-3.36	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	4	ATP1A2
3.466e-02	-3.36	synaptic signaling	biological process	GO:0099536	459	4	18204	49	SLC1A2,NTRK2,SLC1A3,DTNA
3.474e-02	-3.36	PTP4A2 (protein tyrosine phosphatase 4A2)	protein interactions	8073	114	2	19454	50	PON2,FMN2
3.475e-02	-3.36	Melanogenesis	KEGG pathways	ko04916	101	2	7161	21	ADCY2,PRKCA
3.475e-02	-3.36	Melanogenesis	KEGG pathways	hsa04916	101	2	7161	21	ADCY2,PRKCA
3.484e-02	-3.36	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	28	ITPR2
3.484e-02	-3.36	FGFR3c ligand binding and activation	REACTOME pathways	R-HSA-190372	13	1	10285	28	FGFR3
3.484e-02	-3.36	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	28	NRG3
3.484e-02	-3.36	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	28	AQP4
3.484e-02	-3.36	Phospholipase C-mediated cascade; FGFR3	REACTOME pathways	R-HSA-5654227	13	1	10285	28	FGFR3
3.484e-02	-3.36	FGFR3 ligand binding and activation	REACTOME pathways	R-HSA-190239	13	1	10285	28	FGFR3
3.500e-02	-3.35	Cadherin_CS	interpro domains	IPR020894	109	2	18521	50	CDH20,PCDH9
3.514e-02	-3.35	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	47	16828	48	SFXN5,MSI2,CTNND2,DPP10,SLC1A2,NHSL1,FGFR3,FBXL7,ITPR2,GPM6A,EFEMP1,PREX2,ZBTB20,PCDH9,BMPR1B,NPAS3,MGAT4C,HPSE2,SPARCL1,ABLIM1,DTNA,ADCY2,LSAMP,TNIK,NFIB,PARD3B,AQP4,ATP13A4,NRG3,PITPNC1,MACF1,SOX5,GLIS3,PTPRZ1,NTRK2,NFIA,CSGALNACT1,FMN2,QKI,SLC1A3,PRKCA,NEBL,ATP1A2,NTM,LIFR,PON2,CDH20
3.514e-02	-3.35	bile_duct	COSMIC cancer mutations	bile_duct	15095	47	16828	48	ABLIM1,DTNA,SPARCL1,ADCY2,LSAMP,PCDH9,BMPR1B,NPAS3,MGAT4C,HPSE2,ITPR2,GPM6A,ZBTB20,EFEMP1,PREX2,MSI2,SFXN5,CTNND2,DPP10,NHSL1,SLC1A2,FGFR3,FBXL7,ATP1A2,NEBL,NTM,LIFR,PON2,CDH20,NFIA,CSGALNACT1,QKI,FMN2,PRKCA,SLC1A3,ATP13A4,NRG3,PITPNC1,AQP4,MACF1,SOX5,GLIS3,PTPRZ1,NTRK2,TNIK,PARD3B,NFIB
3.518e-02	-3.35	chondroitin sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6569	16	1	902	2	CSGALNACT1
3.520e-02	-3.35	TyrKc	smart domains	SM00219	80	2	9717	36	NTRK2,FGFR3
3.528e-02	-3.34	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	12	16828	48	PREX2,CDH20,PON2,MACF1,SPARCL1,PARD3B,FGFR3,NHSL1,SLC1A3,NPAS3,FMN2,NFIA
3.528e-02	-3.34	alveolar	COSMIC cancer mutations	alveolar	2414	12	16828	48	FMN2,NPAS3,MACF1,SPARCL1,NFIA,FGFR3,PARD3B,PON2,PREX2,SLC1A3,CDH20,NHSL1
3.530e-02	-3.34	HMG20B (high mobility group 20B)	protein interactions	10362	115	2	19454	50	NFIB,SOX5
3.530e-02	-3.34	SMAD7 (SMAD family member 7)	protein interactions	4092	115	2	19454	50	BMPR1B,SOX5
3.530e-02	-3.34	TBXT (T-box transcription factor T)	protein interactions	6862	115	2	19454	50	NFIB,NFIA
3.538e-02	-3.34	Glucagon signaling pathway	KEGG pathways	hsa04922	102	2	7161	21	ADCY2,ITPR2
3.538e-02	-3.34	Glucagon signaling pathway	KEGG pathways	ko04922	102	2	7161	21	ADCY2,ITPR2
3.540e-02	-3.34	Asap1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain1)	protein interactions	13196	14	1	19454	50	MACF1
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	TAS2R7 (taste 2 receptor member 7)	protein interactions	50837	14	1	19454	50	PRKCA
3.540e-02	-3.34	CHAT (choline O-acetyltransferase)	protein interactions	1103	14	1	19454	50	PRKCA
3.540e-02	-3.34	FGF7 (fibroblast growth factor 7)	protein interactions	2252	14	1	19454	50	FGFR3
3.540e-02	-3.34	ZNF628 (zinc finger protein 628)	protein interactions	89887	14	1	19454	50	EFEMP1
3.540e-02	-3.34	RHEBL1 (RHEB like 1)	protein interactions	121268	14	1	19454	50	BMPR1B
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	BOD1L2 (biorientation of chromosomes in cell division 1 like 2)	protein interactions	284257	14	1	19454	50	FMN2
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.540e-02	-3.34	PLXNA4 (plexin A4)	protein interactions	91584	14	1	19454	50	GPM6A
3.553e-02	-3.34	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	40	NTRK2
3.559e-02	-3.34	side of membrane	cellular component	GO:0098552	715	5	19108	49	AQP4,DTNA,LSAMP,LIFR,NTM
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr6q24.1	chromosome location	human chr6q24.1	19	1	26134	50	NHSL1
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.586e-02	-3.33	RDH11 (retinol dehydrogenase 11)	protein interactions	51109	116	2	19454	50	PON2,PRKCA
3.586e-02	-3.33	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	2	19454	50	MACF1,SPARCL1
3.611e-02	-3.32	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	2	16828	48	NRG3,QKI
3.613e-02	-3.32	RET signaling	REACTOME pathways	R-HSA-8853659	270	3	10285	28	NRG3,FGFR3,PRKCA
3.633e-02	-3.32	env (Envelope surface glycoprotein gp160, precursor)	protein interactions	155971	1501	8	19454	50	ADCY2,NTRK2,BMPR1B,SLC1A2,MGAT4C,EFEMP1,PRKCA,PON2
3.642e-02	-3.31	ELK3 (ETS transcription factor ELK3)	protein interactions	2004	117	2	19454	50	NFIA,NFIB
3.645e-02	-3.31	MIR	smart domains	SM00472	10	1	9717	36	ITPR2
3.647e-02	-3.31	skin-back-carcinoma-basal_cell_carcinoma	COSMIC cancer mutations	skin-back-carcinoma-basal_cell_carcinoma	13	1	16828	48	FGFR3
3.647e-02	-3.31	Brenner_tumour	COSMIC cancer mutations	Brenner_tumour	13	1	16828	48	FGFR3
3.647e-02	-3.31	cervix-carcinoma-adenocarcinoma	COSMIC cancer mutations	cervix-carcinoma-adenocarcinoma	13	1	16828	48	FGFR3
3.647e-02	-3.31	endometrium-ovary-endometriosis	COSMIC cancer mutations	endometrium-ovary-endometriosis	13	1	16828	48	FGFR3
3.647e-02	-3.31	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	48	PREX2
3.647e-02	-3.31	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	48	QKI
3.647e-02	-3.31	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	48	PREX2
3.647e-02	-3.31	HYOU1 (hypoxia up-regulated 1)	protein interactions	10525	284	3	19454	50	EFEMP1,PRKCA,FGFR3
3.652e-02	-3.31	microtubule minus-end binding	molecular function	GO:0051011	14	1	18094	48	MACF1
3.657e-02	-3.31	regulation of gliogenesis	biological process	GO:0014013	112	2	18204	49	QKI,PTPRZ1
3.668e-02	-3.31	CAV1 (caveolin 1)	protein interactions	857	719	5	19454	50	MACF1,SLC1A3,FMN2,TNIK,DTNA
3.670e-02	-3.31	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	48	ITPR2,PITPNC1,PARD3B
3.680e-02	-3.30	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	protein interactions	5033	285	3	19454	50	DTNA,EFEMP1,PON2
3.695e-02	-3.30	MAPK signaling pathway	KEGG pathways	hsa04010	255	3	7161	21	NTRK2,FGFR3,PRKCA
3.695e-02	-3.30	MAPK signaling pathway	KEGG pathways	ko04010	255	3	7161	21	NTRK2,PRKCA,FGFR3
3.699e-02	-3.30	ARID3A (AT-rich interaction domain 3A)	protein interactions	1820	118	2	19454	50	NFIA,NFIB
3.699e-02	-3.30	DNM1 (dynamin 1)	protein interactions	1759	118	2	19454	50	GPM6A,PRKCA
3.699e-02	-3.30	VSIG8 (V-set and immunoglobulin domain containing 8)	protein interactions	391123	118	2	19454	50	SPARCL1,CSGALNACT1
3.704e-02	-3.30	cell surface receptor signaling pathway	biological process	GO:0007166	1992	10	18204	49	NFIA,EFEMP1,NTRK2,BMPR1B,TNIK,CTNND2,FGFR3,MACF1,LIFR,NRG3
3.704e-02	-3.30	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	49	AQP4
3.704e-02	-3.30	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	49	ATP1A2
3.704e-02	-3.30	mechanosensory behavior	biological process	GO:0007638	14	1	18204	49	SLC1A3
3.704e-02	-3.30	response to forskolin	biological process	GO:1904321	14	1	18204	49	ADCY2
3.704e-02	-3.30	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	49	SLC1A2
3.704e-02	-3.30	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	49	ATP1A2
3.704e-02	-3.30	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	49	ATP1A2
3.704e-02	-3.30	cellular response to ethanol	biological process	GO:0071361	14	1	18204	49	ITPR2
3.704e-02	-3.30	cellular response to forskolin	biological process	GO:1904322	14	1	18204	49	ADCY2
3.706e-02	-3.30	vascular process in circulatory system	biological process	GO:0003018	273	3	18204	49	ATP1A2,SLC1A3,SLC1A2
3.709e-02	-3.29	cellular homeostasis	biological process	GO:0019725	689	5	18204	49	ATP13A4,ZBTB20,SLC1A3,ATP1A2,AQP4
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	skin-leg-malignant_melanoma-nodular	COSMIC cancer mutations	skin-leg-malignant_melanoma-nodular	258	3	16828	48	PTPRZ1,ATP13A4,FMN2
3.717e-02	-3.29	dendrite development	biological process	GO:0016358	113	2	18204	49	PREX2,CTNND2
3.735e-02	-3.29	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	45	16828	48	HPSE2,MGAT4C,NPAS3,BMPR1B,PCDH9,LSAMP,ADCY2,DTNA,ABLIM1,SPARCL1,FBXL7,FGFR3,SLC1A2,DPP10,CTNND2,MSI2,SFXN5,ZBTB20,EFEMP1,PREX2,GPM6A,ITPR2,PRKCA,SLC1A3,FMN2,QKI,CSGALNACT1,NFIA,CDH20,PON2,LIFR,NTM,NEBL,ATP1A2,PARD3B,NFIB,TNIK,NTRK2,PTPRZ1,GLIS3,SOX5,MACF1,NRG3,ATP13A4,PITPNC1
3.735e-02	-3.29	bladder	COSMIC cancer mutations	bladder	14112	45	16828	48	ITPR2,GPM6A,ZBTB20,EFEMP1,PREX2,CTNND2,DPP10,MSI2,SFXN5,FGFR3,FBXL7,SLC1A2,ADCY2,ABLIM1,DTNA,SPARCL1,LSAMP,BMPR1B,NPAS3,PCDH9,HPSE2,MGAT4C,MACF1,SOX5,PITPNC1,ATP13A4,NRG3,NTRK2,GLIS3,PTPRZ1,TNIK,NFIB,PARD3B,NTM,LIFR,ATP1A2,NEBL,PON2,CDH20,CSGALNACT1,QKI,FMN2,NFIA,PRKCA,SLC1A3
3.738e-02	-3.29	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-humerus-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	107	2	16828	48	PARD3B,NEBL
3.745e-02	-3.28	PARD3 (par-3 family cell polarity regulator)	protein interactions	56288	287	3	19454	50	PARD3B,DTNA,NTRK2
3.747e-02	-3.28	Synthesis of PE	REACTOME pathways	R-HSA-1483213	14	1	10285	28	ETNPPL
3.747e-02	-3.28	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	28	NRG3
3.747e-02	-3.28	DCC mediated attractive signaling	REACTOME pathways	R-HSA-418885	14	1	10285	28	ABLIM1
3.749e-02	-3.28	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	4	ATP1A2
3.749e-02	-3.28	Succinate Signalling During Inflammation	SMPDB pathways	SMP0084634	13	1	1369	4	PRKCA
3.759e-02	-3.28	human chr5q12.3	chromosome location	human chr5q12.3	20	1	26134	50	MAST4
3.777e-02	-3.28	VASP (vasodilator stimulated phosphoprotein)	protein interactions	7408	288	3	19454	50	NEBL,FMN2,NHSL1
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	TNIK
3.788e-02	-3.27	ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive))	protein interactions	957	15	1	19454	50	PRKCA
3.788e-02	-3.27	TAFA5 (TAFA chemokine like family member 5)	protein interactions	25817	15	1	19454	50	NEBL
3.788e-02	-3.27	PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)	protein interactions	27344	15	1	19454	50	MGAT4C
3.788e-02	-3.27	ADRA1B (adrenoceptor alpha 1B)	protein interactions	147	15	1	19454	50	PRKCA
3.788e-02	-3.27	IGSF1 (immunoglobulin superfamily member 1)	protein interactions	3547	15	1	19454	50	BMPR1B
3.788e-02	-3.27	OGG1 (8-oxoguanine DNA glycosylase)	protein interactions	4968	15	1	19454	50	PRKCA
3.788e-02	-3.27	XIRP1 (xin actin binding repeat containing 1)	protein interactions	165904	15	1	19454	50	NEBL
3.788e-02	-3.27	FGF9 (fibroblast growth factor 9)	protein interactions	2254	15	1	19454	50	FGFR3
3.788e-02	-3.27	GRM7 (glutamate metabotropic receptor 7)	protein interactions	2917	15	1	19454	50	PRKCA
3.788e-02	-3.27	Cry1 (cryptochrome circadian regulator 1)	protein interactions	12952	15	1	19454	50	NFIB
3.788e-02	-3.27	FN3K (fructosamine 3 kinase)	protein interactions	64122	15	1	19454	50	PRKCA
3.788e-02	-3.27	MIP	pfam domains	PF00230	14	1	17795	49	AQP4
3.798e-02	-3.27	Cadherin-like_dom	interpro domains	IPR002126	114	2	18521	50	PCDH9,CDH20
3.799e-02	-3.27	PROTEIN_KINASE_TYR	prosite domains	PS00109	94	2	12186	40	NTRK2,FGFR3
3.800e-02	-3.27	upper_leg	COSMIC cancer mutations	upper_leg	880	6	16828	48	PREX2,GLIS3,FGFR3,NFIA,PCDH9,FMN2
3.806e-02	-3.27	positive regulation of MAPK cascade	biological process	GO:0043410	473	4	18204	49	FGFR3,PRKCA,NTRK2,TNIK
3.808e-02	-3.27	learning or memory	biological process	GO:0007611	276	3	18204	49	PTPRZ1,ATP1A2,NTRK2
3.811e-02	-3.27	Cadherin	pfam domains	PF00028	112	2	17795	49	CDH20,PCDH9
3.818e-02	-3.27	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	8	16828	48	HPSE2,PARD3B,ITPR2,MACF1,CTNND2,PCDH9,ATP13A4,ATP1A2
3.819e-02	-3.27	membrane raft	cellular component	GO:0045121	290	3	19108	49	SLC1A2,ADCY2,ATP1A2
3.843e-02	-3.26	BCOR (BCL6 corepressor)	protein interactions	54880	290	3	19454	50	NFIB,NFIA,SOX5
3.855e-02	-3.26	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	48	SLC1A3,SLC1A2
3.855e-02	-3.26	calcium channel activity	molecular function	GO:0005262	117	2	18094	48	GPM6A,ITPR2
3.866e-02	-3.25	S_TKc	smart domains	SM00220	348	4	9717	36	PRKCA,MAST4,TNIK,BMPR1B
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	NFIA,QKI
3.884e-02	-3.25	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	47	16828	48	FGFR3,FBXL7,NHSL1,SLC1A2,CTNND2,DPP10,MSI2,SFXN5,ZBTB20,EFEMP1,PREX2,NKAIN3,ITPR2,GPM6A,HPSE2,MGAT4C,BMPR1B,NPAS3,PCDH9,LSAMP,ADCY2,ABLIM1,DTNA,SPARCL1,NFIB,PARD3B,TNIK,NTRK2,GLIS3,PTPRZ1,MACF1,SOX5,ATP13A4,NRG3,PITPNC1,AQP4,PRKCA,SLC1A3,CSGALNACT1,QKI,FMN2,NFIA,CDH20,NTM,LIFR,NEBL,ATP1A2
3.885e-02	-3.25	membrane microdomain	cellular component	GO:0098857	292	3	19108	49	ATP1A2,ADCY2,SLC1A2
3.887e-02	-3.25	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	18	16828	48	PTPRZ1,CDH20,PREX2,GLIS3,PON2,ADCY2,MACF1,SPARCL1,AQP4,FGFR3,PARD3B,SLC1A3,NHSL1,NPAS3,FMN2,DPP10,CTNND2,NFIA
3.892e-02	-3.25	Ras signaling in the CD4+ TCR pathway	Pathway Interaction DB	tcrraspathway	11	1	2226	8	PRKCA
3.908e-02	-3.24	filamin binding	molecular function	GO:0031005	15	1	18094	48	NEBL
3.908e-02	-3.24	phosphatidylglycerol binding	molecular function	GO:1901611	15	1	18094	48	PITPNC1
3.908e-02	-3.24	tropomyosin binding	molecular function	GO:0005523	15	1	18094	48	NEBL
3.920e-02	-3.24	Cadherin-like_sf	interpro domains	IPR015919	116	2	18521	50	PCDH9,CDH20
3.922e-02	-3.24	soft_tissue-small_round_cell_tumour	COSMIC cancer mutations	soft_tissue-small_round_cell_tumour	14	1	16828	48	FGFR3
3.922e-02	-3.24	endometriosis	COSMIC cancer mutations	endometriosis	14	1	16828	48	FGFR3
3.922e-02	-3.24	in_situ_neoplasm	COSMIC cancer mutations	in_situ_neoplasm	14	1	16828	48	FGFR3
3.922e-02	-3.24	small_round_cell_tumour	COSMIC cancer mutations	small_round_cell_tumour	14	1	16828	48	FGFR3
3.922e-02	-3.24	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma	14	1	16828	48	FGFR3
3.930e-02	-3.24	BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex)	protein interactions	55845	122	2	19454	50	NHSL1,DTNA
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.948e-02	-3.23	glycoprotein biosynthetic process	biological process	GO:0009101	280	3	18204	49	MGAT4C,BMPR1B,CSGALNACT1
3.953e-02	-3.23	chondroitin sulfate biosynthesis	BIOCYC pathways	META_PWY-6569	18	1	902	2	CSGALNACT1
3.964e-02	-3.23	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	49	ATP1A2
3.964e-02	-3.23	synapse maturation	biological process	GO:0060074	15	1	18204	49	NFIA
3.964e-02	-3.23	chondrocyte proliferation	biological process	GO:0035988	15	1	18204	49	FGFR3
3.964e-02	-3.23	regulation of neuron projection arborization	biological process	GO:0150011	15	1	18204	49	MACF1
3.964e-02	-3.23	neuroblast division	biological process	GO:0055057	15	1	18204	49	SOX5
3.964e-02	-3.23	protein homotrimerization	biological process	GO:0070207	15	1	18204	49	SLC1A2
3.964e-02	-3.23	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	49	NTRK2
3.964e-02	-3.23	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	49	ATP1A2
3.964e-02	-3.23	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	49	NTRK2
3.975e-02	-3.23	FH2_Formin	interpro domains	IPR015425	15	1	18521	50	FMN2
3.975e-02	-3.23	FH2_Formin_sf	interpro domains	IPR042201	15	1	18521	50	FMN2
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.988e-02	-3.22	PAX7 (paired box 7)	protein interactions	5081	123	2	19454	50	NFIB,NFIA
3.990e-02	-3.22	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	42	AQP4
4.009e-02	-3.22	WNT5A-dependent internalization of FZD4	REACTOME pathways	R-HSA-5099900	15	1	10285	28	PRKCA
4.009e-02	-3.22	Inhibition of adenylate cyclase pathway	REACTOME pathways	R-HSA-997269	15	1	10285	28	ADCY2
4.009e-02	-3.22	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	28	NRG3
4.009e-02	-3.22	Adenylate cyclase inhibitory pathway	REACTOME pathways	R-HSA-170670	15	1	10285	28	ADCY2
4.009e-02	-3.22	Depolymerisation of the Nuclear Lamina	REACTOME pathways	R-HSA-4419969	15	1	10285	28	PRKCA
4.009e-02	-3.22	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	28	MGAT4C
4.010e-02	-3.22	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	3	16828	48	CDH20,SOX5,LIFR
4.020e-02	-3.21	MAPRE1 (microtubule associated protein RP/EB family member 1)	protein interactions	22919	504	4	19454	50	MAST4,PRKCA,MACF1,ABLIM1
4.020e-02	-3.21	synapse assembly	biological process	GO:0007416	118	2	18204	49	NRG3,GPM6A
4.027e-02	-3.21	postsynaptic density, intracellular component	cellular component	GO:0099092	16	1	19108	49	TNIK
4.035e-02	-3.21	AMMECR1L (AMMECR1 like)	protein interactions	83607	16	1	19454	50	MACF1
4.035e-02	-3.21	RHO (rhodopsin)	protein interactions	6010	16	1	19454	50	PRKCA
4.035e-02	-3.21	HLA-H (major histocompatibility complex, class I, H (pseudogene))	protein interactions	3136	16	1	19454	50	FGFR3
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKCA
4.035e-02	-3.21	SLC6A9 (solute carrier family 6 member 9)	protein interactions	6536	16	1	19454	50	PRKCA
4.035e-02	-3.21	CTSK (cathepsin K)	protein interactions	1513	16	1	19454	50	FGFR3
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	MACF1
4.035e-02	-3.21	WWC3 (WWC family member 3)	protein interactions	55841	16	1	19454	50	PRKCA
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	NRGN (neurogranin)	protein interactions	4900	16	1	19454	50	PRKCA
4.035e-02	-3.21	GABRB3 (gamma-aminobutyric acid type A receptor subunit beta3)	protein interactions	2562	16	1	19454	50	PRKCA
4.035e-02	-3.21	CNTFR (ciliary neurotrophic factor receptor)	protein interactions	1271	16	1	19454	50	LIFR
4.053e-02	-3.21	FH2	pfam domains	PF02181	15	1	17795	49	FMN2
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	TNIK
4.053e-02	-3.21	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	49	ATP1A2
4.054e-02	-3.21	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	49	MACF1,CTNND2,TNIK
4.065e-02	-3.20	membrane protein complex	cellular component	GO:0098796	1261	7	19108	49	SLC1A3,BMPR1B,PRKCA,SLC1A2,CDH20,DPP10,ATP1A2
4.101e-02	-3.19	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	50	FGFR3,NTM,LSAMP,NTRK2
4.106e-02	-3.19	STXBP1 (syntaxin binding protein 1)	protein interactions	6812	125	2	19454	50	GPM6A,PRKCA
4.106e-02	-3.19	SOCS6 (suppressor of cytokine signaling 6)	protein interactions	9306	125	2	19454	50	BMPR1B,EFEMP1
4.144e-02	-3.18	striated muscle contraction	biological process	GO:0006941	120	2	18204	49	ATP1A2,DTNA
4.163e-02	-3.18	water channel activity	molecular function	GO:0015250	16	1	18094	48	AQP4
4.163e-02	-3.18	diacylglycerol-dependent serine/threonine kinase activity	molecular function	GO:0004697	16	1	18094	48	PRKCA
4.163e-02	-3.18	adenylate cyclase activity	molecular function	GO:0004016	16	1	18094	48	ADCY2
4.166e-02	-3.18	ETV3 (ETS variant transcription factor 3)	protein interactions	2117	126	2	19454	50	NFIB,NFIA
4.166e-02	-3.18	SYP (synaptophysin)	protein interactions	6855	126	2	19454	50	GPM6A,PITPNC1
4.196e-02	-3.17	ureter	COSMIC cancer mutations	ureter	15	1	16828	48	FGFR3
4.196e-02	-3.17	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	48	QKI
4.196e-02	-3.17	Serotonergic synapse	KEGG pathways	hsa04726	112	2	7161	21	ITPR2,PRKCA
4.198e-02	-3.17	ossification	biological process	GO:0001503	287	3	18204	49	FGFR3,CSGALNACT1,BMPR1B
4.215e-02	-3.17	Bone Morphogenic Protein (BMP) Signalling and Regulation	WikiPathways	WP1425	12	1	5310	19	BMPR1B
4.223e-02	-3.16	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	49	ATP1A2
4.223e-02	-3.16	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	49	SLC1A2
4.223e-02	-3.16	asymmetric cell division	biological process	GO:0008356	16	1	18204	49	SOX5
4.223e-02	-3.16	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	49	ATP1A2
4.223e-02	-3.16	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	49	ATP1A2
4.223e-02	-3.16	positive regulation of macrophage differentiation	biological process	GO:0045651	16	1	18204	49	PRKCA
4.223e-02	-3.16	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	49	SLC1A3
4.223e-02	-3.16	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	49	ATP1A2
4.267e-02	-3.15	neuron projection terminus	cellular component	GO:0044306	128	2	19108	49	NTRK2,SLC1A2
4.269e-02	-3.15	Formin, FH2 domain	gene3d domains	1.20.58.2220	15	1	14470	42	FMN2
4.271e-02	-3.15	PKA activation	REACTOME pathways	R-HSA-163615	16	1	10285	28	ADCY2
4.271e-02	-3.15	Regulation of KIT signaling	REACTOME pathways	R-HSA-1433559	16	1	10285	28	PRKCA
4.271e-02	-3.15	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	28	NRG3
4.271e-02	-3.15	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	28	NRG3
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	CYP3A4 (cytochrome P450 family 3 subfamily A member 4)	protein interactions	1576	17	1	19454	50	PRKCA
4.282e-02	-3.15	PDE7A (phosphodiesterase 7A)	protein interactions	5150	17	1	19454	50	PRKCA
4.282e-02	-3.15	TNNT2 (troponin T2, cardiac type)	protein interactions	7139	17	1	19454	50	PRKCA
4.282e-02	-3.15	SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)	protein interactions	51091	17	1	19454	50	ABLIM1
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	ZNF358 (zinc finger protein 358)	protein interactions	140467	17	1	19454	50	EFEMP1
4.282e-02	-3.15	RASL12 (RAS like family 12)	protein interactions	51285	17	1	19454	50	BMPR1B
4.282e-02	-3.15	LIPT1 (lipoyltransferase 1)	protein interactions	51601	17	1	19454	50	PRKCA
4.282e-02	-3.15	Sqstm1 (sequestosome 1)	protein interactions	18412	17	1	19454	50	BMPR1B
4.282e-02	-3.15	MSANTD2 (Myb/SANT DNA binding domain containing 2)	protein interactions	79684	17	1	19454	50	SOX5
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.286e-02	-3.15	ATF7IP (activating transcription factor 7 interacting protein)	protein interactions	55729	128	2	19454	50	SOX5,MACF1
4.286e-02	-3.15	PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta)	protein interactions	5577	128	2	19454	50	PRKCA,GPM6A
4.311e-02	-3.14	human chr5p15.31	chromosome location	human chr5p15.31	23	1	26134	50	ADCY2
4.312e-02	-3.14	regulation of multicellular organismal development	biological process	GO:2000026	1484	8	18204	49	QKI,BMPR1B,PRKCA,NTRK2,EFEMP1,PTPRZ1,SOX5,MACF1
4.318e-02	-3.14	Cadherins	gene3d domains	2.60.40.60	114	2	14470	42	PCDH9,CDH20
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	SOX5,ZBTB20
4.346e-02	-3.14	ZNF148 (zinc finger protein 148)	protein interactions	7707	129	2	19454	50	NFIA,NFIB
4.350e-02	-3.13	modulation of chemical synaptic transmission	biological process	GO:0050804	494	4	18204	49	ATP1A2,NTRK2,NRG3,SLC1A3
4.377e-02	-3.13	regulation of trans-synaptic signaling	biological process	GO:0099177	495	4	18204	49	NTRK2,SLC1A3,NRG3,ATP1A2
4.379e-02	-3.13	pleura	COSMIC cancer mutations	pleura	4914	20	16828	48	FBXL7,FGFR3,NFIB,PRKCA,FMN2,QKI,BMPR1B,CTNND2,TNIK,MSI2,NTRK2,PTPRZ1,PREX2,LIFR,NTM,SOX5,ITPR2,NEBL,ATP13A4,PITPNC1
4.381e-02	-3.13	TYRKINASE	prints domains	PR00109	98	2	5227	18	FGFR3,NTRK2
4.389e-02	-3.13	actin cytoskeleton	cellular component	GO:0015629	520	4	19108	49	FMN2,MACF1,NEBL,ABLIM1
4.397e-02	-3.12	action potential	biological process	GO:0001508	124	2	18204	49	NTRK2,ATP1A2
4.404e-02	-3.12	EF-hand	gene3d domains	1.10.238.10	272	3	14470	42	SPARCL1,MACF1,DTNA
4.417e-02	-3.12	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	1	18094	48	PTPRZ1
4.417e-02	-3.12	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	1	18094	48	PTPRZ1
4.419e-02	-3.12	CDH1 (cadherin 1)	protein interactions	999	757	5	19454	50	ABLIM1,CTNND2,MACF1,NHSL1,NEBL
4.445e-02	-3.11	Glycosaminoglycan metabolism	REACTOME pathways	R-HSA-1630316	124	2	10285	28	CSGALNACT1,HPSE2
4.446e-02	-3.11	G Protein Signaling Pathways	WikiPathways	WP35	95	2	5310	19	ADCY2,PRKCA
4.448e-02	-3.11	PDZ	pfam domains	PF00595	122	2	17795	49	PREX2,PARD3B
4.469e-02	-3.11	urinary_tract-carcinoma	COSMIC cancer mutations	urinary_tract-carcinoma	16	1	16828	48	FGFR3
4.469e-02	-3.11	normal	COSMIC cancer mutations	normal	16	1	16828	48	FGFR3
4.469e-02	-3.11	flank	COSMIC cancer mutations	flank	16	1	16828	48	FGFR3
4.469e-02	-3.11	renal_pelvis	COSMIC cancer mutations	renal_pelvis	16	1	16828	48	FGFR3
4.471e-02	-3.11	Thyroid hormone signaling pathway	KEGG pathways	hsa04919	116	2	7161	21	ATP1A2,PRKCA
4.481e-02	-3.11	cell population proliferation	biological process	GO:0008283	726	5	18204	49	SOX5,NFIB,FGFR3,NFIA,HPSE2
4.481e-02	-3.11	viral genome replication	biological process	GO:0019079	17	1	18204	49	NFIA
4.481e-02	-3.11	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	49	ATP1A2
4.481e-02	-3.11	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	49	ATP1A2
4.481e-02	-3.11	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	49	NTRK2
4.481e-02	-3.11	ureter development	biological process	GO:0072189	17	1	18204	49	NFIA
4.481e-02	-3.11	microvillus assembly	biological process	GO:0030033	17	1	18204	49	TNIK
4.481e-02	-3.11	heparin metabolic process	biological process	GO:0030202	17	1	18204	49	CSGALNACT1
4.481e-02	-3.11	protein trimerization	biological process	GO:0070206	17	1	18204	49	SLC1A2
4.493e-02	-3.10	regulation of ERK1 and ERK2 cascade	biological process	GO:0070372	295	3	18204	49	FGFR3,NTRK2,PRKCA
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	A/G_cyclase_CS	interpro domains	IPR018297	17	1	18521	50	ADCY2
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.509e-02	-3.10	PIP3 activates AKT signaling	REACTOME pathways	R-HSA-1257604	125	2	10285	28	FGFR3,NRG3
4.529e-02	-3.09	Cnot2 (CCR4-NOT transcription complex, subunit 2)	protein interactions	72068	18	1	19454	50	MACF1
4.529e-02	-3.09	KLHL1 (kelch like family member 1)	protein interactions	57626	18	1	19454	50	BMPR1B
4.529e-02	-3.09	Tgfbr1 (transforming growth factor, beta receptor I)	protein interactions	21812	18	1	19454	50	BMPR1B
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKCA
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	TTC29 (tetratricopeptide repeat domain 29)	protein interactions	83894	18	1	19454	50	MACF1
4.529e-02	-3.09	NECTIN1 (nectin cell adhesion molecule 1)	protein interactions	5818	18	1	19454	50	FGFR3
4.529e-02	-3.09	NKIRAS1 (NFKB inhibitor interacting Ras like 1)	protein interactions	28512	18	1	19454	50	BMPR1B
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	NEBL
4.532e-02	-3.09	PKA-mediated phosphorylation of CREB	REACTOME pathways	R-HSA-111931	17	1	10285	28	ADCY2
4.532e-02	-3.09	Elevation of cytosolic Ca2+ levels	REACTOME pathways	R-HSA-139853	17	1	10285	28	ITPR2
4.532e-02	-3.09	PKA activation in glucagon signalling	REACTOME pathways	R-HSA-164378	17	1	10285	28	ADCY2
4.532e-02	-3.09	Trafficking of GluR2-containing AMPA receptors	REACTOME pathways	R-HSA-416993	17	1	10285	28	PRKCA
4.533e-02	-3.09	purine ribonucleoside triphosphate binding	molecular function	GO:0035639	1804	9	18094	48	PRKCA,ADCY2,NTRK2,ATP13A4,MAST4,BMPR1B,ATP1A2,TNIK,FGFR3
4.553e-02	-3.09	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	48	ATP1A2,TNIK,PREX2
4.581e-02	-3.08	Carb_anhydrase	pfam domains	PF00194	17	1	17795	49	PTPRZ1
4.581e-02	-3.08	ZZ	pfam domains	PF00569	17	1	17795	49	DTNA
4.585e-02	-3.08	ErbB receptor signaling network	Pathway Interaction DB	erbb_network_pathway	13	1	2226	8	NRG3
4.590e-02	-3.08	cell-cell junction assembly	biological process	GO:0007043	127	2	18204	49	CDH20,PRKCA
4.590e-02	-3.08	regulation of myeloid leukocyte differentiation	biological process	GO:0002761	127	2	18204	49	PRKCA,QKI
4.590e-02	-3.08	response to amino acid	biological process	GO:0043200	127	2	18204	49	NTRK2,SLC1A2
4.595e-02	-3.08	cAMP signaling	KEGG pathways	hsa_M00695	16	1	7161	21	ADCY2
4.595e-02	-3.08	cAMP signaling	KEGG pathways	M00695	16	1	7161	21	ADCY2
4.595e-02	-3.08	N-glycan biosynthesis, complex type	KEGG pathways	M00075	16	1	7161	21	MGAT4C
4.595e-02	-3.08	N-glycan biosynthesis, complex type	KEGG pathways	hsa_M00075	16	1	7161	21	MGAT4C
4.598e-02	-3.08	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	48	CTNND2,FMN2
4.615e-02	-3.08	cell cortex	cellular component	GO:0005938	313	3	19108	49	PARD3B,ITPR2,FMN2
4.653e-02	-3.07	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	2	19454	50	GPM6A,NTM
4.655e-02	-3.07	myelination	biological process	GO:0042552	128	2	18204	49	NTRK2,QKI
4.671e-02	-3.06	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	48	NRG3
4.671e-02	-3.06	phosphatidylcholine transporter activity	molecular function	GO:0008525	18	1	18094	48	PITPNC1
4.671e-02	-3.06	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	48	ITPR2
4.671e-02	-3.06	heparan sulfate proteoglycan binding	molecular function	GO:0043395	18	1	18094	48	HPSE2
4.674e-02	-3.06	GRB2 (growth factor receptor bound protein 2)	protein interactions	2885	769	5	19454	50	FGFR3,PON2,MSI2,NTRK2,SLC1A2
4.706e-02	-3.06	GAB1 signalosome	REACTOME pathways	R-HSA-180292	128	2	10285	28	NRG3,FGFR3
4.706e-02	-3.06	PI3K/AKT activation	REACTOME pathways	R-HSA-198203	128	2	10285	28	FGFR3,NRG3
4.715e-02	-3.05	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	48	DTNA,FGFR3,QKI
4.716e-02	-3.05	Myo1c (myosin IC)	protein interactions	17913	135	2	19454	50	ABLIM1,ITPR2
4.716e-02	-3.05	SOX15 (SRY-box transcription factor 15)	protein interactions	6665	135	2	19454	50	NFIB,NFIA
4.720e-02	-3.05	MINTRINSICP	prints domains	PR00783	14	1	5227	18	AQP4
4.738e-02	-3.05	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	49	NEBL
4.738e-02	-3.05	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	49	NTRK2
4.738e-02	-3.05	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	49	ATP1A2
4.738e-02	-3.05	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	49	CTNND2
4.742e-02	-3.05	verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.742e-02	-3.05	breast-carcinoma-neuroendocrine_carcinoma	COSMIC cancer mutations	breast-carcinoma-neuroendocrine_carcinoma	17	1	16828	48	FGFR3
4.742e-02	-3.05	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	48	QKI
4.742e-02	-3.05	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.742e-02	-3.05	non_chronically_sun_exposed_site	COSMIC cancer mutations	non_chronically_sun_exposed_site	17	1	16828	48	FGFR3
4.742e-02	-3.05	squamous_cell_carcinoma_BRAF_inhibitor_related	COSMIC cancer mutations	squamous_cell_carcinoma_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.742e-02	-3.05	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	48	QKI
4.742e-02	-3.05	skin-non_chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-non_chronically_sun_exposed_site-malignant_melanoma	17	1	16828	48	FGFR3
4.742e-02	-3.05	skin-other-verrucal_keratosis_BRAF_inhibitor_related	COSMIC cancer mutations	skin-other-verrucal_keratosis_BRAF_inhibitor_related	17	1	16828	48	FGFR3
4.752e-02	-3.05	Nucleotide_cyclase	interpro domains	IPR029787	18	1	18521	50	ADCY2
4.752e-02	-3.05	A/G_cyclase	interpro domains	IPR001054	18	1	18521	50	ADCY2
4.752e-02	-3.05	Leu-rich_rpt_Cys-con_subtyp	interpro domains	IPR006553	18	1	18521	50	FBXL7
4.753e-02	-3.05	Oocyte meiosis	KEGG pathways	hsa04114	120	2	7161	21	ITPR2,ADCY2
4.753e-02	-3.05	Oocyte meiosis	KEGG pathways	ko04114	120	2	7161	21	ADCY2,ITPR2
4.754e-02	-3.05	ZYX (zyxin)	protein interactions	7791	316	3	19454	50	MACF1,NEBL,ABLIM1
4.761e-02	-3.04	postsynaptic density	cellular component	GO:0014069	317	3	19108	49	CTNND2,NTRK2,TNIK
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.764e-02	-3.04	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	1	19108	49	GPM6A
4.764e-02	-3.04	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	1	19108	49	TNIK
4.769e-02	-3.04	SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	57154	533	4	19454	50	TNIK,BMPR1B,PRKCA,FMN2
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator)	protein interactions	6236	19	1	19454	50	PRKCA
4.774e-02	-3.04	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	1	19454	50	GPM6A
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	JSRP1 (junctional sarcoplasmic reticulum protein 1)	protein interactions	126306	19	1	19454	50	PRKCA
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	GCHFR (GTP cyclohydrolase I feedback regulator)	protein interactions	2644	19	1	19454	50	NEBL
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	LIFR
4.774e-02	-3.04	CNTNAP4 (contactin associated protein family member 4)	protein interactions	85445	19	1	19454	50	MACF1
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.774e-02	-3.04	ZNF791 (zinc finger protein 791)	protein interactions	163049	19	1	19454	50	EFEMP1
4.774e-02	-3.04	ZNF627 (zinc finger protein 627)	protein interactions	199692	19	1	19454	50	EFEMP1
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	TRPV6 (transient receptor potential cation channel subfamily V member 6)	protein interactions	55503	19	1	19454	50	PRKCA
4.786e-02	-3.04	axon ensheathment	biological process	GO:0008366	130	2	18204	49	QKI,NTRK2
4.786e-02	-3.04	ensheathment of neurons	biological process	GO:0007272	130	2	18204	49	QKI,NTRK2
4.792e-02	-3.04	SHC-mediated cascade:FGFR3	REACTOME pathways	R-HSA-5654704	18	1	10285	28	FGFR3
4.792e-02	-3.04	PI-3K cascade:FGFR3	REACTOME pathways	R-HSA-5654710	18	1	10285	28	FGFR3
4.802e-02	-3.04	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	48	16828	48	MGAT4C,HPSE2,PCDH9,BMPR1B,NPAS3,LSAMP,ABLIM1,DTNA,SPARCL1,ADCY2,NHSL1,SLC1A2,FGFR3,FBXL7,MSI2,SFXN5,CTNND2,DPP10,ZBTB20,PREX2,EFEMP1,NKAIN3,ITPR2,GPM6A,PRKCA,SLC1A3,NFIA,CSGALNACT1,FMN2,QKI,PON2,CDH20,NEBL,ATP1A2,NTM,LIFR,PARD3B,NFIB,TNIK,GLIS3,PTPRZ1,NTRK2,PITPNC1,NRG3,ATP13A4,AQP4,MACF1,SOX5
4.815e-02	-3.03	FH2	prosite domains	PS51444	15	1	12186	40	FMN2
4.815e-02	-3.03	CNH	prosite domains	PS50219	15	1	12186	40	TNIK
4.822e-02	-3.03	mitotic cell cycle process	biological process	GO:1903047	511	4	18204	49	FBXL7,PRKCA,NFIB,NFIA
4.824e-02	-3.03	Alpha carbonic anhydrase	gene3d domains	3.10.200.10	17	1	14470	42	PTPRZ1
4.842e-02	-3.03	CLUH (clustered mitochondria homolog)	protein interactions	23277	137	2	19454	50	FGFR3,PRKCA
4.844e-02	-3.03	Guanylate_cyc	pfam domains	PF00211	18	1	17795	49	ADCY2
4.852e-02	-3.03	carboxylic acid transmembrane transport	biological process	GO:1905039	131	2	18204	49	SLC1A3,SLC1A2
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.859e-02	-3.02	human chr2p16.1	chromosome location	human chr2p16.1	26	1	26134	50	EFEMP1
4.881e-02	-3.02	cytoskeleton organization	biological process	GO:0007010	1251	7	18204	49	MAST4,TNIK,FMN2,ABLIM1,MACF1,PARD3B,NEBL
4.894e-02	-3.02	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	16	16828	48	PRKCA,NFIB,FGFR3,FBXL7,MSI2,TNIK,CTNND2,BMPR1B,QKI,PTPRZ1,PREX2,NTRK2,PITPNC1,ITPR2,SOX5,LIFR
4.900e-02	-3.02	ERK Pathway in Huntington's Disease	WikiPathways	WP3853	14	1	5310	19	NTRK2
4.905e-02	-3.01	NFIB (nuclear factor I B)	protein interactions	4781	138	2	19454	50	NFIA,SOX5
4.906e-02	-3.01	Role of LAT2/NTAL/LAB on calcium mobilization	REACTOME pathways	R-HSA-2730905	131	2	10285	28	FGFR3,NRG3
4.924e-02	-3.01	alkali metal ion binding	molecular function	GO:0031420	19	1	18094	48	ATP1A2
4.924e-02	-3.01	water transmembrane transporter activity	molecular function	GO:0005372	19	1	18094	48	AQP4
4.924e-02	-3.01	transmembrane receptor protein serine/threonine kinase activity	molecular function	GO:0004675	19	1	18094	48	BMPR1B
4.940e-02	-3.01	ACTA1 (actin alpha 1, skeletal muscle)	protein interactions	58	321	3	19454	50	MACF1,PRKCA,DTNA
4.961e-02	-3.00	CADHERIN_1	prosite domains	PS00232	109	2	12186	40	PCDH9,CDH20
4.966e-02	-3.00	cell division	biological process	GO:0051301	516	4	18204	49	SOX5,FBXL7,PARD3B,FMN2
4.969e-02	-3.00	Platelet activation	KEGG pathways	hsa04611	123	2	7161	21	ITPR2,ADCY2
4.985e-02	-3.00	regulation of sequestering of calcium ion	biological process	GO:0051282	133	2	18204	49	ATP1A2,ITPR2
4.995e-02	-3.00	microvillus organization	biological process	GO:0032528	19	1	18204	49	TNIK
4.995e-02	-3.00	response to potassium ion	biological process	GO:0035864	19	1	18204	49	ATP1A2
4.995e-02	-3.00	chondroitin sulfate biosynthetic process	biological process	GO:0030206	19	1	18204	49	CSGALNACT1
4.995e-02	-3.00	regulation of neurotransmitter uptake	biological process	GO:0051580	19	1	18204	49	ATP1A2
4.995e-02	-3.00	vascular associated smooth muscle cell differentiation	biological process	GO:0035886	19	1	18204	49	QKI
4.995e-02	-3.00	positive regulation of bone resorption	biological process	GO:0045780	19	1	18204	49	PRKCA