TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols WP2431 Spinal Cord Injury 0.00818272042565643 -4.8057306132831 119 3 0.157894736842105 19 5310 5803,361,5578 PTPRZ1,AQP4,PRKCA WP2267 Synaptic Vesicle Pathway 0.0144609624795553 -4.23630250294829 52 2 0.105263157894737 19 5310 477,6507 ATP1A2,SLC1A3 WP673 ErbB Signaling Pathway 0.0155399354791509 -4.16434208597204 54 2 0.105263157894737 19 5310 10718,5578 NRG3,PRKCA WP536 Calcium Regulation in the Cardiac Cell 0.0156357916028684 -4.15819265917374 151 3 0.157894736842105 19 5310 3709,5578,108 ITPR2,PRKCA,ADCY2 WP289 Myometrial Relaxation and Contraction Pathways 0.0176472520081641 -4.03717520131277 158 3 0.157894736842105 19 5310 108,3709,5578 ADCY2,ITPR2,PRKCA WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 0.0188595633144272 -3.97073515610495 162 3 0.157894736842105 19 5310 6507,4915,361 SLC1A3,NTRK2,AQP4 WP474 Endochondral Ossification 0.0220668165918405 -3.8136803105382 65 2 0.105263157894737 19 5310 6660,2261 SOX5,FGFR3 WP2374 Oncostatin M Signaling Pathway 0.02270822729001 -3.78502798447547 66 2 0.105263157894737 19 5310 5578,3977 PRKCA,LIFR WP136 Phase I biotransformations, non P450 0.0282877176452559 -3.56532757400857 8 1 0.0526315789473684 19 5310 5445 PON2 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation 0.0421456562537418 -3.166623654323 12 1 0.0526315789473684 19 5310 658 BMPR1B WP35 G Protein Signaling Pathways 0.0444573884837073 -3.11322411072935 95 2 0.105263157894737 19 5310 108,5578 ADCY2,PRKCA WP3853 ERK Pathway in Huntington's Disease 0.0490042106783381 -3.01584905235249 14 1 0.0526315789473684 19 5310 4915 NTRK2 WP2064 Neural Crest Differentiation 0.0505362033868289 -2.98506530080089 102 2 0.105263157894737 19 5310 2261,6660 FGFR3,SOX5 WP3 Transcriptional activation by NRF2 0.052416015814173 -2.94854308904651 15 1 0.0526315789473684 19 5310 5578 PRKCA WP3413 NOTCH1 regulation of human endothelial cell calcification 0.0625819908574834 -2.77127772824833 18 1 0.0526315789473684 19 5310 2261 FGFR3 WP1602 Nicotine Activity on Dopaminergic Neurons 0.0726445839378167 -2.6221764418093 21 1 0.0526315789473684 19 5310 108 ADCY2 WP1528 Physiological and Pathological Hypertrophy of the Heart 0.0859022741707922 -2.4545449757115 25 1 0.0526315789473684 19 5310 3977 LIFR WP2035 Follicle Stimulating Hormone (FSH) signaling pathway 0.0924635891750458 -2.38094034249664 27 1 0.0526315789473684 19 5310 5578 PRKCA WP2583 T-Cell Receptor and Co-stimulatory Signaling 0.0989802695203817 -2.31283474648391 29 1 0.0526315789473684 19 5310 5578 PRKCA WP34 Ovarian Infertility Genes 0.108672227116414 -2.21941901780972 32 1 0.0526315789473684 19 5310 658 BMPR1B WP2828 Bladder Cancer 0.108672227116414 -2.21941901780972 32 1 0.0526315789473684 19 5310 2261 FGFR3 WP2197 Endothelin Pathways 0.111880871997615 -2.190320616635 33 1 0.0526315789473684 19 5310 5578 PRKCA WP3676 BDNF-TrkB Signaling 0.111880871997615 -2.190320616635 33 1 0.0526315789473684 19 5310 4915 NTRK2 WP244 Alpha 6 Beta 4 signaling pathway 0.1182653626847 -2.13482434305323 35 1 0.0526315789473684 19 5310 5578 PRKCA WP3298 Melatonin metabolism and effects 0.121441278912442 -2.10832443416133 36 1 0.0526315789473684 19 5310 5578 PRKCA WP2012 miRs in Muscle Cell Differentiation 0.121441278912442 -2.10832443416133 36 1 0.0526315789473684 19 5310 5578 PRKCA WP1471 Target Of Rapamycin (TOR) Signaling 0.124606355838883 -2.08259566398687 37 1 0.0526315789473684 19 5310 5578 PRKCA WP2447 Amyotrophic lateral sclerosis (ALS) 0.127760628402205 -2.05759685647285 38 1 0.0526315789473684 19 5310 6506 SLC1A2 WP2636 Common Pathways Underlying Drug Addiction 0.140270370283524 -1.96418350246275 42 1 0.0526315789473684 19 5310 5578 PRKCA WP410 Diurnally Regulated Genes with Circadian Orthologs 0.161754427821042 -1.82167597150259 49 1 0.0526315789473684 19 5310 9444 QKI WP363 Wnt Signaling Pathway Netpath 0.173801634869341 -1.74984065958208 53 1 0.0526315789473684 19 5310 5578 PRKCA WP2272 Pathogenic Escherichia coli infection 0.179763548200238 -1.71611291275826 55 1 0.0526315789473684 19 5310 5578 PRKCA WP2795 Cardiac Hypertrophic Response 0.185684688695179 -1.68370526585276 57 1 0.0526315789473684 19 5310 5578 PRKCA WP304 Kit receptor signaling pathway 0.194490526223849 -1.6373718254706 60 1 0.0526315789473684 19 5310 5578 PRKCA WP2324 AGE/RAGE pathway 0.21183228330371 -1.55196043389985 66 1 0.0526315789473684 19 5310 5578 PRKCA WP3651 Pathways Affected in Adenoid Cystic Carcinoma 0.21183228330371 -1.55196043389985 66 1 0.0526315789473684 19 5310 4781 NFIB WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway 0.217533839598151 -1.52540085619607 68 1 0.0526315789473684 19 5310 108 ADCY2 WP428 Wnt Signaling Pathway 0.223196307062943 -1.49970359402878 70 1 0.0526315789473684 19 5310 5578 PRKCA WP2261 Signaling Pathways in Glioblastoma 0.259066895989901 -1.35066896495731 83 1 0.0526315789473684 19 5310 5578 PRKCA WP2355 Corticotropin-releasing hormone signaling pathway 0.28558576966855 -1.25321287584858 93 1 0.0526315789473684 19 5310 5578 PRKCA WP399 Wnt Signaling Pathway and Pluripotency 0.318717828395548 -1.1434491181271 106 1 0.0526315789473684 19 5310 5578 PRKCA WP236 Adipogenesis 0.378384532398049 -0.971844318966382 131 1 0.0526315789473684 19 5310 3977 LIFR WP2858 Ectoderm Differentiation 0.405232964178057 -0.903293157058583 143 1 0.0526315789473684 19 5310 1501 CTNND2 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 0.407420030888074 -0.897910608778889 144 1 0.0526315789473684 19 5310 4915 NTRK2 WP2059 Alzheimers Disease 0.416092343732326 -0.876848063229033 148 1 0.0526315789473684 19 5310 3709 ITPR2 WP51 Regulation of Actin Cytoskeleton 0.418241558280701 -0.871696122748179 149 1 0.0526315789473684 19 5310 2261 FGFR3 WP2857 Mesodermal Commitment Pathway 0.43098029524393 -0.841692908615099 155 1 0.0526315789473684 19 5310 23499 MACF1 WP481 Insulin Signaling 0.443454468244971 -0.813160147113989 161 1 0.0526315789473684 19 5310 5578 PRKCA WP437 EGF/EGFR Signaling Pathway 0.445508141798867 -0.808539756595471 162 1 0.0526315789473684 19 5310 5578 PRKCA WP2377 Integrated Pancreatic Cancer Pathway 0.513027965380891 -0.667424921884126 197 1 0.0526315789473684 19 5310 5578 PRKCA WP707 DNA Damage Response 0.999999999984461 -1.55388002200899e-11 69 0 0 19 5310 WP176 Folate Metabolism 0.999999999984461 -1.55388002200899e-11 69 0 0 19 5310 WP2369 Histone Modifications 0.999999999984461 -1.55388002200899e-11 69 0 0 19 5310 WP2359 Parkin-Ubiquitin Proteasomal System pathway 0.999999999985344 -1.46557680209654e-11 70 0 0 19 5310 WP3871 Valproic acid pathway 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP1434 Osteopontin Signaling 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP2881 Estrogen Receptor Pathway 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP186 Homologous recombination 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP1423 Ganglio Sphingolipid Metabolism 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP3892 Development of pulmonary dendritic cells and macrophage subsets 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation 0.999999999986881 -1.31194286338476e-11 13 0 0 19 5310 WP710 DNA Damage Response (only ATM dependent) 0.999999999989062 -1.09376599930862e-11 114 0 0 19 5310 WP3527 Preimplantation Embryo 0.999999999989966 -1.00343772595347e-11 60 0 0 19 5310 WP558 Complement and Coagulation Cascades 0.999999999989966 -1.00343772595347e-11 60 0 0 19 5310 WP497 Urea cycle and metabolism of amino groups 0.99999999999041 -9.59022802628309e-12 20 0 0 19 5310 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling 0.99999999999041 -9.59022802628309e-12 20 0 0 19 5310 WP516 Hypertrophy Model 0.99999999999041 -9.59022802628309e-12 20 0 0 19 5310 WP1422 Sphingolipid Metabolism 0.99999999999041 -9.59022802628309e-12 20 0 0 19 5310 WP1742 TP53 Network 0.99999999999041 -9.59022802628309e-12 20 0 0 19 5310 WP391 Mitochondrial Gene Expression 0.99999999999041 -9.59022802628309e-12 20 0 0 19 5310 WP477 Cytoplasmic Ribosomal Proteins 0.99999999999085 -9.14983974620114e-12 90 0 0 19 5310 WP138 Androgen receptor signaling pathway 0.99999999999085 -9.14983974620114e-12 90 0 0 19 5310 WP3845 Canonical and Non-canonical Notch signaling 0.999999999990999 -9.00143742197961e-12 27 0 0 19 5310 WP2509 Nanoparticle triggered autophagic cell death 0.999999999991018 -8.98206363450397e-12 24 0 0 19 5310 WP334 GPCRs, Class B Secretin-like 0.999999999991018 -8.98206363450397e-12 24 0 0 19 5310 WP262 EBV LMP1 signaling 0.999999999991018 -8.98206363450397e-12 24 0 0 19 5310 WP1539 Angiogenesis 0.999999999991018 -8.98206363450397e-12 24 0 0 19 5310 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia 0.999999999991018 -8.98206363450397e-12 24 0 0 19 5310 WP560 TGF-beta Receptor Signaling 0.999999999991443 -8.55697115121409e-12 58 0 0 19 5310 WP183 Proteasome Degradation 0.999999999991739 -8.26125894384108e-12 66 0 0 19 5310 WP195 IL-1 signaling pathway 0.999999999991742 -8.25775686065484e-12 57 0 0 19 5310 WP716 Vitamin A and Carotenoid Metabolism 0.999999999992373 -7.62743962296607e-12 44 0 0 19 5310 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 0.999999999992373 -7.62743962296607e-12 44 0 0 19 5310 WP2332 Interleukin-11 Signaling Pathway 0.999999999992373 -7.62743962296607e-12 44 0 0 19 5310 WP2526 PDGF Pathway 0.999999999992514 -7.48583915856312e-12 38 0 0 19 5310 WP383 Striated Muscle Contraction 0.999999999992514 -7.48583915856312e-12 38 0 0 19 5310 WP2029 Cell Differentiation - Index 0.999999999992514 -7.48583915856312e-12 38 0 0 19 5310 WP500 Glycogen Metabolism 0.99999999999258 -7.42017443539479e-12 36 0 0 19 5310 WP585 Interferon type I signaling pathways 0.999999999993377 -6.62347702629972e-12 55 0 0 19 5310 WP395 IL-4 Signaling Pathway 0.999999999993377 -6.62347702629972e-12 55 0 0 19 5310 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway 0.999999999993377 -6.62347702629972e-12 55 0 0 19 5310 WP2328 Allograft Rejection 0.999999999993511 -6.48884022106211e-12 80 0 0 19 5310 WP1772 Apoptosis Modulation and Signaling 0.999999999993892 -6.10794887160912e-12 94 0 0 19 5310 WP231 TNF alpha Signaling Pathway 0.999999999993892 -6.10794887160912e-12 94 0 0 19 5310 WP2491 Diclofenac Metabolic Pathway 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP1603 Nicotine Activity on Chromaffin Cells 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP2889 Oxytocin signaling 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP521 Amino acid conjugation of benzoic acid 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP897 Androgen receptor signaling pathway 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP1133 Androgen receptor signaling pathway 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP1941 Peroxisomal beta-oxidation of tetracosanoyl-CoA 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP3633 Caffeine and Theobromine metabolism 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP690 Polyol Pathway 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP2253 Pilocytic astrocytoma 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP733 Serotonin Receptor 2 and STAT3 Signaling 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP3302 eIF5A regulation in response to inhibition of the nuclear export system 0.99999999999408 -5.91976003417622e-12 4 0 0 19 5310 WP100 Glutathione metabolism 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP3645 NAD+ biosynthetic pathways 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP1584 Type II diabetes mellitus 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP272 Blood Clotting Cascade 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP167 Eicosanoid Synthesis 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP545 Complement Activation 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP3599 Transcription factor regulation in adipogenesis 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP357 Fatty Acid Biosynthesis 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP1424 Globo Sphingolipid Metabolism 0.999999999994492 -5.50811675073038e-12 22 0 0 19 5310 WP466 DNA Replication 0.999999999994505 -5.49491807655689e-12 42 0 0 19 5310 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 0.999999999994505 -5.49491807655689e-12 42 0 0 19 5310 WP405 Eukaryotic Transcription Initiation 0.999999999994505 -5.49491807655689e-12 42 0 0 19 5310 WP49 IL-2 Signaling Pathway 0.999999999994505 -5.49491807655689e-12 42 0 0 19 5310 WP1604 Codeine and Morphine Metabolism 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP237 Glucocorticoid & Mineralcorticoid Metabolism 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP2485 NAD Biosynthesis II (from tryptophan) 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP3635 Insulin signalling in human adipocytes (diabetic condition) 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP3655 Hypothetical Craniofacial Development Pathway 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP3407 FTO Obesity Variant Mechanism 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP2276 Glial Cell Differentiation 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP2338 miRNA Biogenesis 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP1589 Folate-Alcohol and Cancer Pathway 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP3634 Insulin signalling in human adipocytes (normal condition) 0.99999999999451 -5.48994501014485e-12 8 0 0 19 5310 WP692 Sulfation Biotransformation Reaction 0.999999999994869 -5.13141897608986e-12 18 0 0 19 5310 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition 0.999999999994869 -5.13141897608986e-12 18 0 0 19 5310 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression 0.999999999994869 -5.13141897608986e-12 18 0 0 19 5310 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds 0.999999999994869 -5.13141897608986e-12 18 0 0 19 5310 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 0.999999999995402 -4.59846327616055e-12 47 0 0 19 5310 WP2911 miRNA targets in ECM and membrane receptors 0.99999999999561 -4.38994703723183e-12 43 0 0 19 5310 WP364 IL-6 signaling pathway 0.99999999999561 -4.38994703723183e-12 43 0 0 19 5310 WP2878 PPAR Alpha Pathway 0.999999999995795 -4.20515059396473e-12 26 0 0 19 5310 WP325 Triacylglyceride Synthesis 0.999999999995795 -4.20515059396473e-12 26 0 0 19 5310 WP26 Signal Transduction of S1P Receptor 0.999999999995795 -4.20515059396473e-12 26 0 0 19 5310 WP530 Cytokines and Inflammatory Response 0.999999999995795 -4.20515059396473e-12 26 0 0 19 5310 WP581 EPO Receptor Signaling 0.999999999995795 -4.20515059396473e-12 26 0 0 19 5310 WP698 Glucuronidation 0.999999999995795 -4.20515059396473e-12 26 0 0 19 5310 WP129 Matrix Metalloproteinases 0.99999999999582 -4.17968836227123e-12 30 0 0 19 5310 WP2870 Extracellular vesicle-mediated signaling in recipient cells 0.99999999999582 -4.17968836227123e-12 30 0 0 19 5310 WP3851 TLR4 Signaling and Tolerance 0.99999999999582 -4.17968836227123e-12 30 0 0 19 5310 WP241 One Carbon Metabolism 0.99999999999582 -4.17968836227123e-12 30 0 0 19 5310 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 0.99999999999582 -4.17968836227123e-12 30 0 0 19 5310 WP2855 Dopaminergic Neurogenesis 0.99999999999582 -4.17968836227123e-12 30 0 0 19 5310 WP98 Prostaglandin Synthesis and Regulation 0.99999999999582 -4.17968836227123e-12 30 0 0 19 5310 WP2846 Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation 0.999999999996222 -3.77756327644964e-12 3 0 0 19 5310 WP3408 Evolocumab Mechanism 0.999999999996222 -3.77756327644964e-12 3 0 0 19 5310 WP531 Mismatch repair 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP2942 DDX1 as a regulatory component of the Drosha microprocessor 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP561 Heme Biosynthesis 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP3297 EV release from cardiac cells and their functional effects 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP3300 Dual hijack model of Vif in HIV infection 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP3593 miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP3875 ATR Signaling 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP288 NLR Proteins 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP3674 Tgif disruption of Shh signaling 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP3585 Cytosine methylation 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP696 Benzo(a)pyrene metabolism 0.999999999996254 -3.74638604766843e-12 9 0 0 19 5310 WP411 mRNA Processing 0.99999999999644 -3.56050926357012e-12 132 0 0 19 5310 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway 0.99999999999644 -3.56050926357012e-12 132 0 0 19 5310 WP2371 Parkinsons Disease Pathway 0.999999999996858 -3.14187924074933e-12 83 0 0 19 5310 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity 0.999999999996928 -3.07163824528717e-12 35 0 0 19 5310 WP3617 Photodynamic therapy-induced NF-kB survival signaling 0.999999999996928 -3.07163824528717e-12 35 0 0 19 5310 WP1544 MicroRNAs in cardiomyocyte hypertrophy 0.999999999997197 -2.80314545353976e-12 102 0 0 19 5310 WP1438 Influenza A virus infection 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP2816 Felbamate Metabolism 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP2943 Hypoxia-mediated EMT and Stemness 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP2366 Butyrate-induced histone acetylation 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP1273 Folic Acid Network 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP2866 mir34a and TGIF2 in osteoclastogenesis 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP2901 Gonadotropin-releasing hormone (GnRH) signaling 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP2646 Lidocaine metabolism 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP1311 Folic Acid Network 0.999999999997233 -2.76749757889571e-12 2 0 0 19 5310 WP2643 Nanoparticle-mediated activation of receptor signaling 0.999999999997289 -2.71066433808412e-12 29 0 0 19 5310 WP3613 Photodynamic therapy-induced unfolded protein response 0.999999999997289 -2.71066433808412e-12 29 0 0 19 5310 WP422 MAPK Cascade 0.999999999997289 -2.71066433808412e-12 29 0 0 19 5310 WP2249 Metastatic brain tumor 0.99999999999729 -2.70985998026994e-12 28 0 0 19 5310 WP2361 Gastric Cancer Network 1 0.99999999999729 -2.70985998026994e-12 28 0 0 19 5310 WP2884 NRF2 pathway 0.999999999997329 -2.67099465562932e-12 143 0 0 19 5310 WP2874 Liver X Receptor Pathway 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP3656 Interleukin-1 Induced Activation of NF-kappa-B 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP496 Steroid Biosynthesis 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP2333 Trans-sulfuration pathway 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP1531 Vitamin D Metabolism 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP704 Methylation Pathways 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP2113 Type III interferon signaling 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP3601 Composition of Lipid Particles 0.999999999997337 -2.66282645512685e-12 10 0 0 19 5310 WP2525 Trans-sulfuration and one carbon metabolism 0.99999999999738 -2.62033845506943e-12 32 0 0 19 5310 WP3858 Toll-like Receptor Signaling 0.99999999999738 -2.62033845506943e-12 32 0 0 19 5310 WP3893 Development and heterogeneity of the ILC family 0.99999999999738 -2.62033845506943e-12 32 0 0 19 5310 WP2875 Constitutive Androstane Receptor Pathway 0.99999999999738 -2.62033845506943e-12 32 0 0 19 5310 WP727 Monoamine Transport 0.99999999999738 -2.62033845506943e-12 32 0 0 19 5310 WP455 GPCRs, Class A Rhodopsin-like 0.99999999999739 -2.6099670944399e-12 259 0 0 19 5310 WP694 Arylamine metabolism 0.999999999997441 -2.55885266227293e-12 6 0 0 19 5310 WP1600 Nicotine Metabolism 0.999999999997441 -2.55885266227293e-12 6 0 0 19 5310 WP1981 Thyroxine (Thyroid Hormone) Production 0.999999999997441 -2.55885266227293e-12 6 0 0 19 5310 WP3891 Benzene metabolism 0.999999999997441 -2.55885266227293e-12 6 0 0 19 5310 WP2516 ATM Signaling Pathway 0.999999999997592 -2.40802249320745e-12 40 0 0 19 5310 WP524 G13 Signaling Pathway 0.999999999997592 -2.40802249320745e-12 40 0 0 19 5310 WP127 IL-5 Signaling Pathway 0.999999999997592 -2.40802249320745e-12 40 0 0 19 5310 WP45 G1 to S cell cycle control 0.999999999997753 -2.24706853530023e-12 68 0 0 19 5310 WP1403 AMP-activated Protein Kinase (AMPK) Signaling 0.999999999997753 -2.24706853530023e-12 68 0 0 19 5310 WP3303 Rac1/Pak1/p38/MMP-2 pathway 0.999999999997753 -2.24706853530023e-12 68 0 0 19 5310 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways 0.999999999997753 -2.24706853530023e-12 68 0 0 19 5310 WP111 Electron Transport Chain 0.999999999997777 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Degradation of Ketone Bodies 0.999999999998729 -1.27146706840907e-12 5 0 0 19 5310 WP688 Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs) 0.999999999998729 -1.27146706840907e-12 5 0 0 19 5310 WP2597 Secretion of Hydrochloric Acid in Parietal Cells 0.999999999998729 -1.27146706840907e-12 5 0 0 19 5310 WP3596 miR-517 relationship with ARCN1 and USP1 0.999999999998729 -1.27146706840907e-12 5 0 0 19 5310 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer 0.999999999998729 -1.27146706840907e-12 5 0 0 19 5310 WP2542 Sulindac Metabolic Pathway 0.999999999998729 -1.27146706840907e-12 5 0 0 19 5310 WP1530 miRNA Regulation of DNA Damage Response 0.999999999998787 -1.21269500923254e-12 93 0 0 19 5310 WP3286 Copper homeostasis 0.999999999999289 -7.11039298901899e-13 54 0 0 19 5310 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer 0.999999999999289 -7.11039298901899e-13 54 0 0 19 5310 WP623 Oxidative phosphorylation 0.999999999999289 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WP313 Signaling of Hepatocyte Growth Factor Receptor 0.999999999999773 -2.27422106863756e-13 34 0 0 19 5310 WP143 Fatty Acid Beta Oxidation 0.999999999999773 -2.27422106863756e-13 34 0 0 19 5310 WP400 p38 MAPK Signaling Pathway 0.999999999999773 -2.27422106863756e-13 34 0 0 19 5310 WP306 Focal Adhesion 1.00000000000001 1.01074515702668e-14 195 0 0 19 5310 WP3865 RIG-I-like Receptor Signaling 1.00000000000016 1.55490758443783e-13 61 0 0 19 5310 WP3624 Lung fibrosis 1.00000000000038 3.82275659336972e-13 63 0 0 19 5310 WP43 Oxidation by Cytochrome P450 1.00000000000038 3.82275659336972e-13 63 0 0 19 5310 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 1.00000000000058 5.81617407578349e-13 74 0 0 19 5310 WP24 Peptide GPCRs 1.00000000000058 5.81617407578349e-13 74 0 0 19 5310 WP404 Nucleotide Metabolism 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP247 Small Ligand GPCRs 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP384 Apoptosis Modulation by HSP70 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP3287 Overview of nanoparticle effects 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP2879 Farnesoid X Receptor Pathway 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP697 Estrogen metabolism 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP22 IL-9 Signaling Pathway 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP1992 TarBasePathway 1.00000000000061 6.11632763094085e-13 19 0 0 19 5310 WP23 B Cell Receptor Signaling Pathway 1.00000000000065 6.45555080221042e-13 98 0 0 19 5310 WP117 GPCRs, Other 1.0000000000014 1.39621967003781e-12 95 0 0 19 5310 WP615 Senescence and Autophagy in Cancer 1.00000000000175 1.75343944470171e-12 106 0 0 19 5310 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 1.00000000000179 1.79215296859702e-12 73 0 0 19 5310 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP53 ID signaling pathway 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP3644 NAD+ metabolism 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP1946 Cori Cycle 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP550 Biogenic Amine Synthesis 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP12 Osteoclast Signaling 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP501 GPCRs, Class C Metabotropic glutamate, pheromone 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP47 Hedgehog Signaling Pathway 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 1.00000000000196 1.95715249329094e-12 16 0 0 19 5310 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 1.00000000000215 2.14574178061437e-12 23 0 0 19 5310 WP712 Estrogen signaling pathway 1.00000000000215 2.14574178061437e-12 23 0 0 19 5310 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 1.00000000000246 2.46316839651267e-12 31 0 0 19 5310 WP2112 IL17 signaling pathway 1.00000000000246 2.46316839651267e-12 31 0 0 19 5310 WP408 Oxidative Stress 1.00000000000246 2.46316839651267e-12 31 0 0 19 5310 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR 1.00000000000252 2.51726389664757e-12 37 0 0 19 5310 WP3614 Photodynamic therapy-induced HIF-1 survival signaling 1.00000000000252 2.51726389664757e-12 37 0 0 19 5310 WP619 Type II interferon signaling (IFNG) 1.00000000000252 2.51726389664757e-12 37 0 0 19 5310 WP3529 Zinc homeostasis 1.00000000000252 2.51726389664757e-12 37 0 0 19 5310 WP430 Statin Pathway 1.00000000000297 2.97148695698738e-12 33 0 0 19 5310 WP453 Inflammatory Response Pathway 1.00000000000297 2.97148695698738e-12 33 0 0 19 5310 WP2363 Gastric Cancer Network 2 1.00000000000297 2.97148695698738e-12 33 0 0 19 5310 WP58 Monoamine GPCRs 1.00000000000297 2.97148695698738e-12 33 0 0 19 5310 WP170 Nuclear Receptors 1.00000000000303 3.034791329847e-12 39 0 0 19 5310 WP2853 Endoderm Differentiation 1.00000000000307 3.07086655420079e-12 145 0 0 19 5310 WP1449 Regulation of toll-like receptor signaling pathway 1.00000000000307 3.07086655420079e-12 145 0 0 19 5310 WP2446 Retinoblastoma (RB) in Cancer 1.00000000000342 3.41678903118763e-12 88 0 0 19 5310 WP661 Glucose Homeostasis 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP108 Selenium metabolism/Selenoproteins 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP1 Statin Pathway 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP188 Focal Adhesion 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP3627 Gut-Liver Indole Metabolism 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP2536 Colchicine Metabolic Pathway 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP3191 TSLP Signaling Pathway 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP2190 One carbon donor 1.00000000000362 3.61691492728466e-12 1 0 0 19 5310 WP3594 Circadian rythm related genes 1.00000000000411 4.11120360070353e-12 207 0 0 19 5310 WP702 Metapathway biotransformation 1.0000000000042 4.20343490553069e-12 177 0 0 19 5310 WP2435 Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis 1.00000000000472 4.71565280896801e-12 15 0 0 19 5310 WP206 Fatty Acid Omega Oxidation 1.00000000000472 4.71565280896801e-12 15 0 0 19 5310 WP197 Cholesterol Biosynthesis 1.00000000000472 4.71565280896801e-12 15 0 0 19 5310 WP699 Aflatoxin B1 metabolism 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP3595 mir-124 predicted interactions with cell cycle and differentiation 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP1995 Effects of Nitric Oxide 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP1272 Selenium Micronutrient Network 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP3924 Hfe effect on hepcidin production 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP2596 Gastric acid production 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP134 Pentose Phosphate Pathway 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP438 Non-homologous end joining 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP1310 Selenium Micronutrient Network 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP2805 RNA interference 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP528 Acetylcholine Synthesis 1.00000000000473 4.72750287286189e-12 7 0 0 19 5310 WP185 Integrin-mediated Cell Adhesion 1.00000000000505 5.05474050835683e-12 103 0 0 19 5310 WP75 Toll-like Receptor Signaling Pathway 1.00000000000505 5.05474050835683e-12 103 0 0 19 5310 WP2895 Differentiation of white and brown adipocyte 1.00000000000556 5.56255951367039e-12 25 0 0 19 5310 WP2865 IL1 and megakaryocytes in obesity 1.00000000000556 5.56255951367039e-12 25 0 0 19 5310 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease 1.00000000000556 5.56255951367039e-12 25 0 0 19 5310 WP205 IL-7 Signaling Pathway 1.00000000000556 5.56255951367039e-12 25 0 0 19 5310 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation 1.00000000000638 6.38031440463386e-12 17 0 0 19 5310 WP3874 Canonical and Non-Canonical TGF-B signaling 1.00000000000638 6.38031440463386e-12 17 0 0 19 5310 WP2289 Drug Induction of Bile Acid Pathway 1.00000000000638 6.38031440463386e-12 17 0 0 19 5310 WP554 ACE Inhibitor Pathway 1.00000000000638 6.38031440463386e-12 17 0 0 19 5310 WP78 TCA Cycle 1.00000000000638 6.38031440463386e-12 17 0 0 19 5310 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 1.00000000000638 6.38031440463386e-12 17 0 0 19 5310 WP2916 Interactome of polycomb repressive complex 2 (PRC2) 1.00000000000638 6.38031440463386e-12 17 0 0 19 5310 WP15 Selenium Micronutrient Network 1.0000000000065 6.50216223842272e-12 87 0 0 19 5310 WP2854 Gene regulatory network modelling somitogenesis 1.00000000000706 7.06469414126961e-12 11 0 0 19 5310 WP1455 Serotonin Transporter Activity 1.00000000000706 7.06469414126961e-12 11 0 0 19 5310 WP2513 Nanoparticle triggered regulated necrosis 1.00000000000706 7.06469414126961e-12 11 0 0 19 5310 WP80 Nucleotide GPCRs 1.00000000000706 7.06469414126961e-12 11 0 0 19 5310 WP3630 NAD metabolism, sirtuins and aging 1.00000000000706 7.06469414126961e-12 11 0 0 19 5310 WP1984 Integrated Breast Cancer Pathway 1.00000000000746 7.45809928366369e-12 154 0 0 19 5310 WP366 TGF-beta Signaling Pathway 1.00000000000747 7.46937228491074e-12 133 0 0 19 5310 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 1.00000000000937 9.36657716526148e-12 62 0 0 19 5310 WP3584 MECP2 and Associated Rett Syndrome 1.00000000000937 9.36657716526148e-12 62 0 0 19 5310 WP61 Notch Signaling Pathway 1.00000000000937 9.36657716526148e-12 62 0 0 19 5310 WP3611 Photodynamic therapy-induced AP-1 survival signaling. 1.00000000001169 1.16925704086952e-11 51 0 0 19 5310 WP3646 Hepatitis C and Hepatocellular Carcinoma 1.00000000001169 1.16925704086952e-11 51 0 0 19 5310