Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
2.904e-15	-33.47	brainstem	COSMIC cancer mutations	brainstem	3102	34	16828	48	SLC1A3,PHYHIPL,HS6ST3,SASH1,PDZRN4,CTNND2,GABBR2,DMD,LSAMP,SMOC1,DPP6,PTPRT,CTNNA3,QKI,PPP2R2B,GPM6A,SLC1A2,SOX6,GABRB1,DCLK1,PRKG1,PCDH9,ZBTB20,NPAS3,SPON1,LIFR,GRID2,PTPRZ1,NRG3,TNIK,GRIK1,CPE,GRIA4,LAMA2
3.000e-15	-33.44	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	38	16828	48	PPP2R2B,CTNNA3,QKI,PTPRT,GPM6A,DPP6,CLU,LSAMP,MYO16,SMOC1,GABBR2,DMD,CTNND2,PDZRN4,AQP4,ATP1A2,NTRK2,SASH1,SPARCL1,HS6ST3,PHYHIPL,SLC1A3,GRIA4,LAMA2,TNIK,NRG3,CPE,GRIA1,GRID2,SPON1,LIFR,DGKG,PCDH9,PRKG1,SLC1A2,DTNA,GABRB1,SOX6
6.851e-15	-32.61	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	29	16828	48	GRIA1,CPE,NRG3,LAMA2,GRIA4,NPAS3,SPON1,GRID2,PCDH9,DGKG,SOX6,GABRB1,SLC1A2,PRKG1,DPP6,GPM6A,PTPRT,CTNNA3,PPP2R2B,GABBR2,SMOC1,MYO16,LSAMP,SASH1,NTRK2,CTNND2,SLC1A3,PHYHIPL,HS6ST3
6.851e-15	-32.61	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	29	16828	48	DPP6,PTPRT,CTNNA3,PPP2R2B,GPM6A,GABBR2,LSAMP,SMOC1,MYO16,NTRK2,SASH1,CTNND2,SLC1A3,PHYHIPL,HS6ST3,NRG3,GRIA1,CPE,LAMA2,GRIA4,NPAS3,SPON1,GRID2,DGKG,PCDH9,SLC1A2,SOX6,GABRB1,PRKG1
3.274e-14	-31.05	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	35	16828	48	HS6ST3,PHYHIPL,AQP4,PDZRN4,CTNND2,SASH1,SPARCL1,ATP1A2,SMOC1,MYO16,LSAMP,DMD,GABBR2,GPM6A,PTPRT,PPP2R2B,QKI,CTNNA3,CLU,DPP6,PRKG1,SOX6,GABRB1,SLC1A2,PCDH9,DGKG,GRID2,LIFR,SPON1,GRIA4,LAMA2,GRIA1,CPE,NRG3,TNIK
8.002e-14	-30.16	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	30	16828	48	PTPRZ1,GRID2,LIFR,SPON1,GRIA4,LAMA2,CPE,TNIK,GRIK1,NRG3,PRKG1,DCLK1,SOX6,GABRB1,ZBTB20,PCDH9,SMOC1,LSAMP,GABBR2,GPM6A,QKI,PPP2R2B,CTNNA3,PTPRT,DPP6,HS6ST3,PHYHIPL,SLC1A3,CTNND2,SASH1
1.662e-13	-29.43	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	28	16828	48	GPM6A,PPP2R2B,CTNNA3,PTPRT,DPP6,MYO16,SMOC1,LSAMP,DMD,GABBR2,CTNND2,SASH1,NTRK2,HS6ST3,PHYHIPL,SLC1A3,GRIA4,LAMA2,GRIA1,NRG3,PTPRZ1,GRID2,SPON1,PCDH9,PRKG1,SOX6,GABRB1,SLC1A2
1.662e-13	-29.43	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	28	16828	48	GPM6A,CTNNA3,PPP2R2B,PTPRT,DPP6,MYO16,SMOC1,LSAMP,DMD,GABBR2,CTNND2,SASH1,NTRK2,HS6ST3,PHYHIPL,SLC1A3,GRIA4,LAMA2,GRIA1,NRG3,PTPRZ1,GRID2,SPON1,PCDH9,PRKG1,GABRB1,SOX6,SLC1A2
1.758e-13	-29.37	synapse	cellular component	GO:0045202	1473	23	19108	49	SLC1A3,DTNA,CLU,SPARCL1,CTNND2,DMD,LAMA2,GABBR2,TNIK,NRG3,GRIK1,GRIA1,QKI,GRIA4,PTPRT,GPM6A,ATP1A2,SLC1A2,GABRB1,GRID2,DCLK1,PTPRZ1,NTRK2
2.068e-13	-29.21	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	28	16828	48	MYO16,SMOC1,LSAMP,DMD,GABBR2,GPM6A,CTNNA3,PPP2R2B,PTPRT,DPP6,HS6ST3,PHYHIPL,SLC1A3,CTNND2,SASH1,NTRK2,PTPRZ1,GRID2,SPON1,GRIA4,LAMA2,GRIA1,NRG3,PRKG1,SOX6,GABRB1,SLC1A2,PCDH9
2.090e-13	-29.20	nervous system development	biological process	GO:0007399	2185	27	18204	48	PCDH9,MYO16,QKI,CTNND2,LSAMP,GRIA1,PTPRZ1,GRID2,GPM6A,NTM,GABRB1,SLC1A2,NRG3,CLU,LAMA2,DGKG,SOX6,ATP1A2,GFAP,TNIK,PRKG1,GRIK1,NTRK2,DCLK1,SLC1A3,DMD,GPM6B
5.477e-12	-25.93	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	29	16828	48	LSAMP,SMOC1,MYO16,GABBR2,PTPRT,CTNNA3,PPP2R2B,GPM6A,DPP6,HS6ST3,SLC1A3,PHYHIPL,PDZRN4,CTNND2,NTRK2,SASH1,GRID2,SPON1,LIFR,LAMA2,GRIA4,NRG3,GRIA1,CPE,PRKG1,SLC1A2,GABRB1,SOX6,PCDH9
1.496e-11	-24.93	cell junction	cellular component	GO:0030054	2224	25	19108	49	GABBR2,PCDH9,LAMA2,CTNNA3,GRIA1,NRG3,GRIK1,TNIK,SLC1A3,DTNA,CLU,DMD,CTNND2,SPARCL1,DCLK1,PTPRZ1,NTRK2,SLC1A2,GPM6A,ATP1A2,GRIA4,QKI,PTPRT,GRID2,GABRB1
1.525e-11	-24.91	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	29	16828	48	GABBR2,MYO16,SMOC1,LSAMP,DPP6,GPM6A,PPP2R2B,CTNNA3,PTPRT,PHYHIPL,SLC1A3,HS6ST3,SASH1,NTRK2,CTNND2,PDZRN4,LIFR,SPON1,GRID2,CPE,GRIA1,NRG3,GRIA4,LAMA2,SOX6,GABRB1,SLC1A2,PRKG1,PCDH9
2.504e-11	-24.41	central nervous system development	biological process	GO:0007417	995	18	18204	48	PRKG1,GRID2,PTPRZ1,GRIA1,GFAP,QKI,ATP1A2,SOX6,MYO16,PCDH9,GPM6B,CLU,NTRK2,DCLK1,GRIK1,GABRB1,SLC1A2,NRG3
2.761e-11	-24.31	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	20	16828	48	AQP4,CTNND2,SASH1,PCDH9,PRKG1,HS6ST3,GABRB1,SOX6,LAMA2,GRIA4,PTPRT,CTNNA3,GRIA1,NRG3,TNIK,SMOC1,MYO16,LSAMP,GRID2,SPON1
3.473e-11	-24.08	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	14	16828	48	NRG3,GRIA4,GPM6A,CTNNA3,PTPRT,GABBR2,LSAMP,GRID2,PCDH9,CTNND2,GABRB1,SOX6,PHYHIPL,PRKG1
3.980e-11	-23.95	postsynapse	cellular component	GO:0098794	646	15	19108	49	ATP1A2,GPM6A,PTPRT,GRIA4,DMD,CTNND2,GRID2,GABRB1,GABBR2,DCLK1,LAMA2,GRIA1,GRIK1,NTRK2,TNIK
3.983e-11	-23.95	neurogenesis	biological process	GO:0022008	1334	20	18204	48	CTNND2,QKI,SOX6,MYO16,GPM6A,TNIK,PRKG1,NTM,GFAP,GRID2,PTPRZ1,NTRK2,DCLK1,CLU,SLC1A3,GABRB1,DGKG,LAMA2,GPM6B,DMD
7.067e-11	-23.37	system development	biological process	GO:0048731	3533	30	18204	48	DGKG,LAMA2,CLU,SLC1A2,NRG3,GABRB1,NTM,GPM6A,GRIA1,PTPRZ1,GRID2,LSAMP,CSMD1,QKI,CTNND2,SMOC1,MYO16,PCDH9,DMD,GPM6B,SLC1A3,DCLK1,NTRK2,GRIK1,PRKG1,TNIK,GFAP,ATP1A2,CPE,SOX6
1.037e-10	-22.99	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	48	CTNND2,SASH1,NTRK2,HS6ST3,SLC1A3,GPM6A,PTPRT,PPP2R2B,CTNNA3,DPP6,NTM,SMOC1,MYO16,LSAMP,GABBR2,ZBTB20,PCDH9,PRKG1,SOX6,GABRB1,SLC1A2,LAMA2,GRIA4,GLIS3,GRIA1,CPE,NRG3,TNIK,GRID2,PTPRZ1,LIFR,SPON1
1.037e-10	-22.99	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	32	16828	48	HS6ST3,SLC1A3,CTNND2,SASH1,NTRK2,MYO16,SMOC1,LSAMP,GABBR2,GPM6A,PPP2R2B,CTNNA3,PTPRT,NTM,DPP6,PRKG1,GABRB1,SOX6,SLC1A2,ZBTB20,PCDH9,PTPRZ1,GRID2,LIFR,SPON1,LAMA2,GRIA4,CPE,GLIS3,GRIA1,TNIK,NRG3
1.586e-10	-22.56	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	14	16828	48	GRID2,LSAMP,PTPRT,PPP2R2B,CTNNA3,GPM6A,GRIA4,LAMA2,NRG3,HS6ST3,PRKG1,GABRB1,CTNND2,PCDH9
1.773e-10	-22.45	cerebellum	COSMIC cancer mutations	cerebellum	769	16	16828	48	PCDH9,NTRK2,CTNND2,GABRB1,PRKG1,CPE,GRIA1,DPP6,NRG3,GRIA4,CTNNA3,QKI,DMD,NPAS3,PTPRZ1,GRID2
1.932e-10	-22.37	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	15	16828	48	GABRB1,PRKG1,NTRK2,PCDH9,CTNND2,NPAS3,DMD,PTPRZ1,GRID2,NRG3,CPE,DPP6,GRIA1,CTNNA3,GRIA4
1.973e-10	-22.35	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	15	16828	48	NPAS3,DMD,PTPRZ1,GRID2,NRG3,CPE,DPP6,GRIA1,CTNNA3,GRIA4,GABRB1,PRKG1,NTRK2,PCDH9,CTNND2
2.318e-10	-22.19	lymph_node	COSMIC cancer mutations	lymph_node	1703	22	16828	48	DTNA,GABRB1,SOX6,PHYHIPL,SLC1A3,PRKG1,DCLK1,PCDH9,NTRK2,CTNND2,LIFR,DMD,GABBR2,SMOC1,LSAMP,GRID2,TNIK,NRG3,GRIA4,GPM6A,CTNNA3,PTPRT
2.867e-10	-21.97	neuron development	biological process	GO:0048666	859	16	18204	48	DGKG,GPM6B,LAMA2,DMD,SLC1A3,DCLK1,NTRK2,GABRB1,NTM,PRKG1,TNIK,GPM6A,PTPRZ1,GFAP,CTNND2,MYO16
2.992e-10	-21.93	cell periphery	cellular component	GO:0071944	6020	37	19108	49	AQP4,CPE,GRIA4,PRKG1,PTPRT,GPM6A,SMOC1,ATP1A2,SLC1A2,DPP6,GABRB1,GRID2,MYO16,LSAMP,NTM,DGKG,DCLK1,PTPRZ1,CST3,GPM6B,NTRK2,MAPK10,SLC1A3,DTNA,CLU,SPARCL1,LIFR,DMD,CTNND2,LAMA2,SPON1,PCDH9,GABBR2,TNIK,NRG3,GRIK1,GRIA1
4.542e-10	-21.51	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	30	16828	48	DMD,LSAMP,MYO16,CLU,DPP6,PTPRT,CTNNA3,PPP2R2B,SLC1A3,HS6ST3,NTRK2,PDZRN4,CTNND2,NPAS3,SPON1,LIFR,GRID2,PTPRZ1,NRG3,TNIK,GRIA1,CPE,GRIA4,LAMA2,GABRB1,SOX6,DTNA,DCLK1,PRKG1,PCDH9
4.542e-10	-21.51	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	30	16828	48	DTNA,GABRB1,SOX6,PRKG1,DCLK1,PCDH9,SPON1,NPAS3,LIFR,PTPRZ1,GRID2,TNIK,NRG3,CPE,GRIA1,GRIA4,LAMA2,SLC1A3,HS6ST3,NTRK2,CTNND2,PDZRN4,DMD,LSAMP,MYO16,DPP6,CLU,CTNNA3,PPP2R2B,PTPRT
6.894e-10	-21.10	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	17	16828	48	GRIA1,NRG3,GRIA4,LAMA2,PTPRT,CTNNA3,SPON1,MYO16,LSAMP,GRID2,PCDH9,SASH1,CTNND2,GABRB1,SOX6,PRKG1,HS6ST3
9.221e-10	-20.80	neuron differentiation	biological process	GO:0030182	1081	17	18204	48	GABRB1,DCLK1,NTRK2,SLC1A3,DMD,LAMA2,GPM6B,DGKG,MYO16,CTNND2,GFAP,PTPRZ1,GRID2,GPM6A,TNIK,PRKG1,NTM
1.297e-09	-20.46	multicellular organism development	biological process	GO:0007275	3957	30	18204	48	NRG3,SLC1A2,GABRB1,CLU,LAMA2,DGKG,SMOC1,PCDH9,MYO16,CSMD1,QKI,CTNND2,GRIA1,GRID2,PTPRZ1,LSAMP,NTM,GPM6A,GRIK1,SLC1A3,DCLK1,NTRK2,DMD,GPM6B,SOX6,CPE,ATP1A2,GFAP,TNIK,PRKG1
1.687e-09	-20.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	15	16828	48	SLC1A2,SOX6,GABRB1,HS6ST3,ATP1A2,NTRK2,PCDH9,GABBR2,LSAMP,GRID2,MYO16,NRG3,DPP6,CTNNA3,PTPRT
1.689e-09	-20.20	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	20	16828	48	CTNND2,PCDH9,NTRK2,DGKG,PRKG1,HS6ST3,GABRB1,SOX6,SLC1A3,LAMA2,GRIA4,CTNNA3,QKI,PPP2R2B,PTPRT,NRG3,MYO16,LSAMP,GRID2,SPON1
1.689e-09	-20.20	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	20	16828	48	PCDH9,DGKG,NTRK2,CTNND2,GABRB1,SOX6,SLC1A3,PRKG1,HS6ST3,NRG3,GRIA4,LAMA2,QKI,CTNNA3,PPP2R2B,PTPRT,SPON1,MYO16,LSAMP,GRID2
2.628e-09	-19.76	generation of neurons	biological process	GO:0048699	1158	17	18204	48	MYO16,CTNND2,GFAP,PTPRZ1,GRID2,GPM6A,NTM,TNIK,PRKG1,GABRB1,DCLK1,NTRK2,SLC1A3,DMD,LAMA2,GPM6B,DGKG
1.048e-08	-18.37	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome	1174	17	16828	48	ATP1A2,NTRK2,PDZRN4,SOX6,GABRB1,SLC1A2,PRKG1,DCLK1,TNIK,NRG3,CTNNA3,PTPRT,GABBR2,NPAS3,MYO16,LSAMP,GRID2
1.048e-08	-18.37	myelodysplastic_syndrome	COSMIC cancer mutations	myelodysplastic_syndrome	1174	17	16828	48	CTNNA3,PTPRT,TNIK,NRG3,MYO16,LSAMP,GRID2,GABBR2,NPAS3,PDZRN4,ATP1A2,NTRK2,PRKG1,DCLK1,GABRB1,SOX6,SLC1A2
1.422e-08	-18.07	postsynaptic specialization	cellular component	GO:0099572	345	10	19108	49	GRID2,GABRB1,TNIK,CTNND2,GRIA1,NTRK2,GRIK1,GRIA4,PTPRT,DCLK1
2.258e-08	-17.61	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	31	16828	48	DTNA,GABRB1,SOX6,PRKG1,DCLK1,DGKG,PCDH9,SPON1,LIFR,PTPRZ1,GRID2,GRIK1,NRG3,GRIA1,GLIS3,GRIA4,SLC1A3,HS6ST3,ATP1A2,SASH1,CTNND2,GABBR2,DMD,MYO16,SMOC1,CLU,DPP6,QKI,CTNNA3,PTPRT,GPM6A
2.258e-08	-17.61	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	31	16828	48	PCDH9,DGKG,DCLK1,PRKG1,SOX6,GABRB1,DTNA,GRIA4,GRIA1,GLIS3,NRG3,GRIK1,GRID2,PTPRZ1,LIFR,SPON1,CTNND2,SASH1,ATP1A2,HS6ST3,SLC1A3,GPM6A,PTPRT,CTNNA3,QKI,DPP6,CLU,SMOC1,MYO16,DMD,GABBR2
2.264e-08	-17.60	synaptic signaling	biological process	GO:0099536	459	11	18204	48	GRID2,GRIA1,DTNA,SLC1A3,NTRK2,GRIA4,GABBR2,GRIK1,SLC1A2,GABRB1,DMD
2.942e-08	-17.34	plasma membrane	cellular component	GO:0005886	5538	33	19108	49	PTPRZ1,DCLK1,DGKG,NTM,LSAMP,MYO16,NTRK2,GPM6B,CST3,SLC1A2,ATP1A2,GPM6A,PTPRT,GRIA4,PRKG1,CPE,AQP4,GRID2,GABRB1,DPP6,PCDH9,GABBR2,LAMA2,GRIA1,GRIK1,NRG3,TNIK,DTNA,SLC1A3,MAPK10,CTNND2,DMD,LIFR
4.709e-08	-16.87	ANF_receptor	pfam domains	PF01094	37	5	17795	48	GRIA1,GABBR2,GRID2,GRIK1,GRIA4
4.769e-08	-16.86	ANF_lig-bd_rcpt	interpro domains	IPR001828	37	5	18521	50	GRIA1,GRIA4,GRID2,GRIK1,GABBR2
5.732e-08	-16.67	synaptic membrane	cellular component	GO:0097060	400	10	19108	49	PTPRT,GRIA4,GABBR2,SLC1A2,GPM6A,GRID2,GABRB1,GRIA1,DMD,GRIK1
6.273e-08	-16.58	Peripla_BP_I	interpro domains	IPR028082	39	5	18521	50	GABBR2,GRID2,GRIK1,GRIA4,GRIA1
6.889e-08	-16.49	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	35	16828	48	NTRK2,SASH1,SPARCL1,CTNND2,PDZRN4,AQP4,PHYHIPL,SLC1A3,HS6ST3,DPP6,CLU,CTNNA3,PPP2R2B,PTPRT,GPM6A,GABBR2,DMD,LSAMP,MYO16,SMOC1,PCDH9,SLC1A2,GABRB1,SOX6,PRKG1,DCLK1,NRG3,GLIS3,GRIA1,GRIA4,LAMA2,SPON1,NPAS3,PTPRZ1,GRID2
8.476e-08	-16.28	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	43	16828	48	NTM,CLU,DPP6,QKI,PPP2R2B,CTNNA3,PTPRT,GPM6A,GABBR2,DMD,LSAMP,MYO16,SMOC1,NTRK2,SASH1,SPARCL1,CTNND2,PDZRN4,PHYHIPL,SLC1A3,HS6ST3,GRIK1,TNIK,NRG3,CPE,GLIS3,GRIA1,GRIA4,LAMA2,SPON1,NPAS3,LIFR,PTPRZ1,GRID2,DGKG,PCDH9,ZBTB20,SLC1A2,DTNA,SOX6,GABRB1,PRKG1,DCLK1
9.633e-08	-16.16	glial cell differentiation	biological process	GO:0010001	219	8	18204	48	GPM6B,GFAP,LAMA2,PTPRZ1,NTRK2,CLU,QKI,SOX6
9.748e-08	-16.14	postsynaptic density	cellular component	GO:0014069	317	9	19108	49	PTPRT,GRIA4,DCLK1,TNIK,GRID2,GRIK1,NTRK2,GRIA1,CTNND2
1.029e-07	-16.09	bone	COSMIC cancer mutations	bone	8157	41	16828	48	GRID2,PTPRZ1,NPAS3,SPON1,LIFR,GRIA4,LAMA2,NRG3,TNIK,GRIA1,GLIS3,CPE,DCLK1,PRKG1,SOX6,GABRB1,DTNA,ZBTB20,DGKG,PCDH9,CST3,LSAMP,SMOC1,MYO16,GABBR2,DMD,PTPRT,PPP2R2B,CTNNA3,QKI,GPM6A,GPM6B,DPP6,HS6ST3,SLC1A3,PDZRN4,CTNND2,NTRK2,ATP1A2,SPARCL1,SASH1
1.043e-07	-16.08	neuron projection	cellular component	GO:0043005	1331	16	19108	49	GRIA1,NTRK2,GABBR2,PCDH9,LAMA2,DMD,CTNND2,GRID2,GABRB1,CLU,DTNA,SLC1A3,SLC1A2,ATP1A2,GPM6A,GRIA4
1.060e-07	-16.06	trunk	COSMIC cancer mutations	trunk	3554	27	16828	48	SMOC1,LSAMP,DMD,GABBR2,PTPRT,PPP2R2B,CTNNA3,SLC1A3,PDZRN4,CTNND2,SPARCL1,SASH1,NTRK2,ATP1A2,GRID2,PTPRZ1,LIFR,NPAS3,GRIA4,LAMA2,GRIA1,GLIS3,CPE,NRG3,DCLK1,PCDH9,DGKG
1.387e-07	-15.79	Lig_chan-Glu_bd	pfam domains	PF10613	18	4	17795	48	GRIA4,GRIA1,GRID2,GRIK1
1.387e-07	-15.79	Lig_chan	pfam domains	PF00060	18	4	17795	48	GRIK1,GRIA1,GRID2,GRIA4
1.398e-07	-15.78	Ionotropic_Glu_rcpt	interpro domains	IPR015683	18	4	18521	50	GRID2,GRIA4,GRIK1,GRIA1
1.398e-07	-15.78	Iono_Glu_rcpt_met	interpro domains	IPR001508	18	4	18521	50	GRIK1,GRID2,GRIA4,GRIA1
1.398e-07	-15.78	Iontro_rcpt_C	interpro domains	IPR001320	18	4	18521	50	GRIA4,GRID2,GRIK1,GRIA1
1.398e-07	-15.78	Glu/Gly-bd	interpro domains	IPR019594	18	4	18521	50	GRIA4,GRIK1,GRID2,GRIA1
1.459e-07	-15.74	trans-synaptic signaling	biological process	GO:0099537	431	10	18204	48	GRIA1,GRID2,DTNA,SLC1A3,NTRK2,GRIK1,GABBR2,GRIA4,GABRB1,SLC1A2
1.481e-07	-15.73	asymmetric synapse	cellular component	GO:0032279	333	9	19108	49	DCLK1,CTNND2,GRIA1,NTRK2,GRIK1,GRIA4,PTPRT,GRID2,TNIK
1.714e-07	-15.58	D-aspartate transmembrane transport	biological process	GO:0070777	5	3	18204	48	SLC1A3,SLC1A2,GFAP
1.714e-07	-15.58	D-aspartate import across plasma membrane	biological process	GO:0070779	5	3	18204	48	GFAP,SLC1A2,SLC1A3
1.860e-07	-15.50	DNAAF2 (dynein axonemal assembly factor 2)	protein interactions	55172	98	6	19454	50	LSAMP,DPP6,GPM6A,PHYHIPL,GPM6B,DCLK1
2.364e-07	-15.26	anatomical structure development	biological process	GO:0048856	5207	31	18204	48	SOX6,CPE,ATP1A2,GFAP,TNIK,PRKG1,SPARCL1,GRIK1,DCLK1,NTRK2,SLC1A3,DMD,GPM6B,MYO16,PCDH9,SMOC1,CSMD1,QKI,CTNND2,LSAMP,GRIA1,GRID2,PTPRZ1,GPM6A,NTM,SLC1A2,NRG3,GABRB1,CLU,LAMA2,DGKG
2.647e-07	-15.14	dendritic spine	cellular component	GO:0043197	172	7	19108	49	GRIA1,ATP1A2,GPM6A,NTRK2,GRID2,GRIA4,LAMA2
2.863e-07	-15.07	neuron spine	cellular component	GO:0044309	174	7	19108	49	LAMA2,GRIA4,GPM6A,ATP1A2,GRID2,NTRK2,GRIA1
2.906e-07	-15.05	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	38	16828	48	NTM,DPP6,GPM6B,GPM6A,CTNNA3,PPP2R2B,QKI,PTPRT,DMD,GABBR2,MYO16,SMOC1,LSAMP,SASH1,NTRK2,CTNND2,SLC1A3,HS6ST3,CPE,GRIA1,GLIS3,TNIK,GRIK1,NRG3,LAMA2,GRIA4,LIFR,SPON1,NPAS3,PTPRZ1,GRID2,PCDH9,DGKG,ZBTB20,GABRB1,SOX6,SLC1A2,PRKG1
3.213e-07	-14.95	neuron to neuron synapse	cellular component	GO:0098984	365	9	19108	49	GRIK1,NTRK2,GRIA1,DCLK1,CTNND2,TNIK,GRID2,PTPRT,GRIA4
3.407e-07	-14.89	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	molecular function	GO:1904315	53	5	18094	50	GRIA1,GABRB1,GRIK1,GRID2,GRIA4
3.422e-07	-14.89	D-amino acid transport	biological process	GO:0042940	6	3	18204	48	GFAP,SLC1A2,SLC1A3
4.113e-07	-14.70	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	molecular function	GO:0099529	55	5	18094	50	GRIK1,GRIA4,GRID2,GABRB1,GRIA1
5.125e-07	-14.48	modulation of chemical synaptic transmission	biological process	GO:0050804	494	10	18204	48	ATP1A2,NTRK2,SLC1A3,NRG3,GRIK1,GRIA4,LAMA2,GFAP,GRIA1,GRID2
5.155e-07	-14.48	postsynaptic membrane	cellular component	GO:0045211	280	8	19108	49	GABBR2,GRIA1,DMD,GRIK1,GRID2,PTPRT,GRIA4,GABRB1
5.221e-07	-14.47	regulation of trans-synaptic signaling	biological process	GO:0099177	495	10	18204	48	GRIA1,GRID2,GFAP,LAMA2,GRIK1,GRIA4,NRG3,SLC1A3,NTRK2,ATP1A2
5.477e-07	-14.42	gliogenesis	biological process	GO:0042063	275	8	18204	48	SOX6,CLU,QKI,NTRK2,PTPRZ1,GFAP,GPM6B,LAMA2
5.517e-07	-14.41	-	gene3d domains	3.40.50.2300	50	5	14470	47	GRIA1,GABBR2,GRIK1,GRIA4,GRID2
5.571e-07	-14.40	mouth	COSMIC cancer mutations	mouth	9004	42	16828	48	GRID2,PTPRZ1,LIFR,NPAS3,SPON1,LAMA2,GRIA4,GRIA1,NRG3,GRIK1,TNIK,DCLK1,PRKG1,GABRB1,SOX6,DTNA,SLC1A2,ZBTB20,PCDH9,DGKG,SMOC1,MYO16,CST3,LSAMP,DMD,GABBR2,GPM6A,PTPRT,GFAP,PPP2R2B,QKI,CTNNA3,DPP6,CLU,NTM,HS6ST3,SLC1A3,PDZRN4,CTNND2,SASH1,NTRK2,ATP1A2
5.871e-07	-14.35	transmitter-gated channel activity	molecular function	GO:0022835	59	5	18094	50	GRIA1,GABRB1,GRIK1,GRIA4,GRID2
5.871e-07	-14.35	transmitter-gated monoatomic ion channel activity	molecular function	GO:0022824	59	5	18094	50	GABRB1,GRIA1,GRID2,GRIA4,GRIK1
7.226e-07	-14.14	PBPe	smart domains	SM00079	18	4	9717	40	GRIK1,GRIA1,GRID2,GRIA4
7.226e-07	-14.14	Lig_chan-Glu_bd	smart domains	SM00918	18	4	9717	40	GRIA1,GRIA4,GRID2,GRIK1
7.374e-07	-14.12	glutamate receptor activity	molecular function	GO:0008066	26	4	18094	50	GRIK1,GRIA4,GRID2,GRIA1
7.716e-07	-14.07	postsynaptic specialization membrane	cellular component	GO:0099634	125	6	19108	49	GRIK1,GRIA1,GABRB1,GRIA4,PTPRT,GRID2
8.103e-07	-14.03	bone-femur-other-chondroblastoma	COSMIC cancer mutations	bone-femur-other-chondroblastoma	183	7	16828	48	PCDH9,NRG3,LAMA2,GRIA4,CTNNA3,HS6ST3,GRID2
8.268e-07	-14.01	Periplasmic binding protein-like II	gene3d domains	3.40.190.10	23	4	14470	47	GRIK1,GRIA1,GRID2,GRIA4
8.373e-07	-13.99	NMDARECEPTOR	prints domains	PR00177	18	4	5227	23	GRIA4,GRIK1,GRID2,GRIA1
1.029e-06	-13.79	cell-cell signaling	biological process	GO:0007267	822	12	18204	48	CPE,GABRB1,SLC1A2,GRIK1,GABBR2,GRIA4,NTRK2,SLC1A3,DMD,DTNA,GRIA1,GRID2
1.164e-06	-13.66	anterograde trans-synaptic signaling	biological process	GO:0098916	415	9	18204	48	SLC1A3,GRIK1,GABBR2,GRIA4,SLC1A2,GABRB1,GRIA1,GRID2,DTNA
1.164e-06	-13.66	chemical synaptic transmission	biological process	GO:0007268	415	9	18204	48	DTNA,GRID2,GRIA1,SLC1A3,SLC1A2,GABRB1,GABBR2,GRIA4,GRIK1
1.372e-06	-13.50	Transmission across Chemical Synapses	REACTOME pathways	R-HSA-112315	217	7	10285	28	GRIK1,SLC1A3,GABBR2,GABRB1,GRIA1,SLC1A2,GRIA4
1.387e-06	-13.49	postsynaptic neurotransmitter receptor activity	molecular function	GO:0098960	70	5	18094	50	GABRB1,GRIA1,GRID2,GRIA4,GRIK1
1.482e-06	-13.42	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	19	19108	49	LAMA2,GABBR2,PCDH9,NTRK2,GRIA1,CTNNA3,AQP4,GRIA4,ATP1A2,GPM6A,DTNA,CLU,SLC1A2,SLC1A3,GFAP,GABRB1,GRID2,CTNND2,DMD
1.597e-06	-13.35	extracellular ligand-gated monoatomic ion channel activity	molecular function	GO:0005230	72	5	18094	50	GRID2,GRIA4,GRIK1,GABRB1,GRIA1
1.629e-06	-13.33	sarcolemma	cellular component	GO:0042383	142	6	19108	49	DMD,DTNA,ATP1A2,PRKG1,AQP4,LAMA2
1.697e-06	-13.29	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	14	16828	48	PRKG1,SOX6,GABRB1,SLC1A2,PHYHIPL,DGKG,SMOC1,GRID2,LAMA2,PTPRT,QKI,CTNNA3,DPP6,NRG3
2.090e-06	-13.08	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	37	16828	48	GABRB1,SOX6,SLC1A2,PRKG1,PCDH9,DGKG,LIFR,SPON1,PTPRZ1,GRID2,CPE,GLIS3,GRIA1,TNIK,GRIK1,NRG3,LAMA2,GRIA4,PHYHIPL,SLC1A3,HS6ST3,SPARCL1,SASH1,NTRK2,CTNND2,DMD,GABBR2,MYO16,SMOC1,LSAMP,CLU,DPP6,GPM6A,CTNNA3,QKI,PPP2R2B,PTPRT
2.148e-06	-13.05	brain development	biological process	GO:0007420	724	11	18204	48	ATP1A2,SOX6,PCDH9,MYO16,PRKG1,GRID2,GRIA1,NTRK2,DCLK1,SLC1A2,NRG3
2.258e-06	-13.00	developmental process	biological process	GO:0032502	5716	31	18204	48	SMOC1,PCDH9,MYO16,CTNND2,QKI,CSMD1,PTPRZ1,GRID2,GRIA1,LSAMP,NTM,GPM6A,SLC1A2,GABRB1,NRG3,CLU,LAMA2,DGKG,SOX6,CPE,ATP1A2,GFAP,PRKG1,TNIK,GRIK1,SPARCL1,SLC1A3,NTRK2,DCLK1,GPM6B,DMD
2.455e-06	-12.92	plasma membrane region	cellular component	GO:0098590	1278	14	19108	49	ATP1A2,GPM6A,SLC1A2,SLC1A3,AQP4,PTPRT,GRIA4,DMD,GABRB1,GRID2,GABBR2,GRIK1,GRIA1,TNIK
2.779e-06	-12.79	tibia	COSMIC cancer mutations	tibia	836	12	16828	48	PTPRT,CTNND2,QKI,GPM6A,LAMA2,TNIK,CPE,LSAMP,DCLK1,MYO16,PRKG1,DMD
2.864e-06	-12.76	regulation of membrane potential	biological process	GO:0042391	463	9	18204	48	NTRK2,ATP1A2,GABRB1,GRIK1,GRIA4,DMD,CTNNA3,GRIA1,GRID2
2.881e-06	-12.76	oligodendrocyte differentiation	biological process	GO:0048709	85	5	18204	48	NTRK2,CLU,GPM6B,SOX6,PTPRZ1
3.082e-06	-12.69	cell projection	cellular component	GO:0042995	2398	19	19108	49	AQP4,GRIA4,ATP1A2,GPM6A,CLU,DTNA,SLC1A3,SLC1A2,GFAP,GABRB1,GRID2,CTNND2,DMD,LAMA2,PCDH9,GABBR2,NTRK2,GRIA1,CTNNA3
3.154e-06	-12.67	dendrite	cellular component	GO:0030425	620	10	19108	49	GRIA1,CTNND2,NTRK2,GRID2,GABRB1,CLU,ATP1A2,GPM6A,GRIA4,LAMA2
3.246e-06	-12.64	dendritic tree	cellular component	GO:0097447	622	10	19108	49	NTRK2,CTNND2,GRIA1,GABRB1,GRID2,GPM6A,ATP1A2,CLU,LAMA2,GRIA4
3.353e-06	-12.61	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	32	16828	48	DCLK1,PRKG1,GABRB1,DTNA,DGKG,GRID2,PTPRZ1,NPAS3,SPON1,LIFR,GRIA4,LAMA2,NRG3,GRIK1,GRIA1,HS6ST3,SLC1A3,CTNND2,NTRK2,ATP1A2,LSAMP,CST3,SMOC1,MYO16,DMD,PTPRT,PPP2R2B,GPM6A,GPM6B,CLU,DPP6,NTM
3.353e-06	-12.61	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	32	16828	48	PTPRZ1,GRID2,LIFR,SPON1,NPAS3,GRIA4,LAMA2,GRIA1,GRIK1,NRG3,PRKG1,DCLK1,DTNA,GABRB1,DGKG,MYO16,SMOC1,CST3,LSAMP,DMD,GPM6B,GPM6A,PPP2R2B,PTPRT,NTM,DPP6,CLU,HS6ST3,SLC1A3,CTNND2,ATP1A2,NTRK2
3.604e-06	-12.53	ionotropic glutamate receptor complex	cellular component	GO:0008328	41	4	19108	49	GRID2,GRIA4,GRIK1,GRIA1
3.631e-06	-12.53	multicellular organismal process	biological process	GO:0032501	6177	32	18204	48	ATP1A2,SOX6,CPE,PRKG1,TNIK,GFAP,DTNA,SLC1A3,DCLK1,NTRK2,GRIK1,GPM6B,DMD,CTNND2,QKI,CSMD1,SMOC1,PCDH9,MYO16,NTM,GPM6A,PTPRZ1,GRID2,GRIA1,LSAMP,AQP4,CLU,NRG3,SLC1A2,GABRB1,DGKG,LAMA2
3.650e-06	-12.52	MAPT (microtubule associated protein tau)	protein interactions	4137	948	12	19454	50	DCLK1,SLC1A2,MAPK10,PPP2R2B,ATP1A2,LSAMP,NTM,CLU,SLC1A3,GPM6A,TNIK,CTNND2
4.088e-06	-12.41	head development	biological process	GO:0060322	774	11	18204	48	PRKG1,GRID2,GRIA1,NTRK2,ATP1A2,DCLK1,SOX6,NRG3,SLC1A2,MYO16,PCDH9
5.345e-06	-12.14	synaptic transmission, glutamatergic	biological process	GO:0035249	44	4	18204	48	GRIA1,GRIK1,GRIA4,GRID2
5.753e-06	-12.07	neurotransmitter receptor complex	cellular component	GO:0098878	46	4	19108	49	GRIK1,GRIA1,GRID2,GRIA4
5.855e-06	-12.05	glutamate receptor signaling pathway	biological process	GO:0007215	45	4	18204	48	GRIK1,GRIA1,GRID2,GRIA4
5.921e-06	-12.04	postsynaptic density membrane	cellular component	GO:0098839	101	5	19108	49	GRIA4,GRID2,PTPRT,GRIK1,GRIA1
6.985e-06	-11.87	neurotransmitter receptor activity	molecular function	GO:0030594	97	5	18094	50	GRIA1,GABRB1,GRIK1,GRID2,GRIA4
7.142e-06	-11.85	somatodendritic compartment	cellular component	GO:0036477	842	11	19108	49	GRIA4,LAMA2,CLU,SLC1A3,ATP1A2,GPM6A,GRID2,GABRB1,GRIA1,CTNND2,NTRK2
7.151e-06	-11.85	cell development	biological process	GO:0048468	2236	18	18204	48	LAMA2,GPM6B,DMD,DGKG,GABRB1,CLU,SLC1A3,NTRK2,DCLK1,PTPRZ1,GFAP,TNIK,NTM,PRKG1,GPM6A,MYO16,CTNND2,QKI
8.109e-06	-11.72	amino acid transmembrane transporter activity	molecular function	GO:0015171	100	5	18094	50	GRIK1,SLC1A2,SLC1A3,GRIA4,GRIA1
8.542e-06	-11.67	regulation of postsynaptic membrane potential	biological process	GO:0060078	106	5	18204	48	GRID2,GRIA4,GRIA1,GRIK1,GABRB1
8.607e-06	-11.66	receptor complex	cellular component	GO:0043235	409	8	19108	49	GABRB1,GRID2,LIFR,GRIK1,NTRK2,GRIA1,GRIA4,GABBR2
9.078e-06	-11.61	glutamatergic synapse	cellular component	GO:0098978	412	8	19108	49	PTPRT,GPM6A,SLC1A2,TNIK,GRID2,SPARCL1,NRG3,GRIA1
9.792e-06	-11.53	cell morphogenesis	biological process	GO:0000902	687	10	18204	48	PTPRZ1,LAMA2,TNIK,PRKG1,GPM6A,MYO16,SLC1A3,CLU,CTNND2,DCLK1
1.023e-05	-11.49	forebrain development	biological process	GO:0030900	408	8	18204	48	NRG3,SLC1A2,PCDH9,ATP1A2,NTRK2,DCLK1,GRIA1,PRKG1
1.056e-05	-11.46	neuron projection development	biological process	GO:0031175	693	10	18204	48	MYO16,DCLK1,CTNND2,GFAP,GPM6B,LAMA2,PTPRZ1,GPM6A,PRKG1,TNIK
1.084e-05	-11.43	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	molecular function	GO:0099507	16	3	18094	50	GABRB1,GRIA1,GRIA4
1.084e-05	-11.43	glutamate-gated receptor activity	molecular function	GO:0004970	16	3	18094	50	GRIA1,GRIA4,GRIK1
1.492e-05	-11.11	astrocyte projection	cellular component	GO:0097449	19	3	19108	49	GFAP,AQP4,SLC1A2
1.618e-05	-11.03	regulation of neurotransmitter uptake	biological process	GO:0051580	19	3	18204	48	ATP1A2,GFAP,GPM6B
1.677e-05	-11.00	NS-malignant_melanoma	COSMIC cancer mutations	NS-malignant_melanoma	3420	23	16828	48	DCLK1,HS6ST3,GABRB1,PHYHIPL,PDZRN4,CTNND2,PCDH9,DGKG,ATP1A2,SMOC1,MYO16,GRID2,PTPRZ1,DMD,LIFR,SPON1,LAMA2,PTPRT,DPP6,GLIS3,GRIA1,NRG3,GRIK1
1.696e-05	-10.98	upper_aerodigestive_tract-mouth-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma	6426	33	16828	48	CLU,DPP6,NTM,PTPRT,GFAP,CTNNA3,PPP2R2B,QKI,GPM6A,GABBR2,DMD,MYO16,SASH1,PDZRN4,CTNND2,SLC1A3,HS6ST3,NRG3,GRIK1,GRIA1,GRIA4,LAMA2,NPAS3,SPON1,LIFR,GRID2,DGKG,ZBTB20,SLC1A2,SOX6,GABRB1,DCLK1,PRKG1
1.892e-05	-10.88	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	26	16828	48	GPM6A,PPP2R2B,CTNNA3,PTPRT,NTM,DPP6,MYO16,SMOC1,DMD,CTNND2,PDZRN4,NTRK2,HS6ST3,GRIA4,LAMA2,GRIA1,TNIK,GRIK1,NRG3,PTPRZ1,LIFR,ZBTB20,PCDH9,PRKG1,DCLK1,GABRB1
1.901e-05	-10.87	aspartate transmembrane transport	biological process	GO:0015810	20	3	18204	48	SLC1A3,GFAP,SLC1A2
1.942e-05	-10.85	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	12	19454	50	QKI,SPARCL1,CLU,CPE,LSAMP,AQP4,ATP1A2,DPP6,PTPRZ1,GPM6A,SLC1A3,DMD
2.134e-05	-10.76	Myelin_PLP	pfam domains	PF01275	3	2	17795	48	GPM6B,GPM6A
2.139e-05	-10.75	Myelin_PLP	interpro domains	IPR001614	3	2	18521	50	GPM6A,GPM6B
2.139e-05	-10.75	Myelin_PLP_CS	interpro domains	IPR018237	3	2	18521	50	GPM6B,GPM6A
2.145e-05	-10.75	bone-humerus-other-chondroblastoma	COSMIC cancer mutations	bone-humerus-other-chondroblastoma	301	7	16828	48	GABRB1,GRID2,PRKG1,PPP2R2B,CTNNA3,GPM6A,GRIA4
2.377e-05	-10.65	NUFIP1 (nuclear FMR1 interacting protein 1)	protein interactions	26747	134	5	19454	50	GPM6A,DCLK1,GPM6B,NTM,CPE
2.562e-05	-10.57	membrane	cellular component	GO:0016020	9220	38	19108	49	GRIA1,GRIK1,HS6ST3,NRG3,PPP2R2B,TNIK,GABBR2,PCDH9,LAMA2,CTNND2,DMD,LIFR,DTNA,CLU,SLC1A3,MAPK10,CSMD1,NTRK2,GPM6B,CST3,PTPRZ1,DCLK1,DGKG,NTM,MYO16,LSAMP,GRID2,GFAP,GABRB1,DPP6,SLC1A2,ATP1A2,GPM6A,PTPRT,GRIA4,PRKG1,CPE,AQP4
2.865e-05	-10.46	anatomical structure morphogenesis	biological process	GO:0009653	2225	17	18204	48	NRG3,DCLK1,NTRK2,CLU,SLC1A3,LAMA2,MYO16,SOX6,CPE,QKI,CSMD1,CTNND2,GRID2,PTPRZ1,GPM6A,TNIK,PRKG1
2.936e-05	-10.44	ionotropic glutamate receptor signaling pathway	biological process	GO:0035235	23	3	18204	48	GRIA4,GRIK1,GRIA1
3.118e-05	-10.38	Neuronal System	REACTOME pathways	R-HSA-112316	349	7	10285	28	GRIA4,SLC1A2,GRIA1,SLC1A3,GRIK1,GABRB1,GABBR2
3.248e-05	-10.33	GPM6A (glycoprotein M6A)	protein interactions	2823	143	5	19454	50	DPP6,CPE,DCLK1,NTM,PHYHIPL
3.471e-05	-10.27	MYELIN_PLP_2	prosite domains	PS01004	3	2	12186	42	GPM6B,GPM6A
3.471e-05	-10.27	MYELIN_PLP_1	prosite domains	PS00575	3	2	12186	42	GPM6A,GPM6B
3.595e-05	-10.23	neuron projection morphogenesis	biological process	GO:0048812	486	8	18204	48	PTPRZ1,LAMA2,MYO16,PRKG1,CTNND2,TNIK,GPM6A,DCLK1
3.866e-05	-10.16	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	8	18204	48	MYO16,DCLK1,CTNND2,LAMA2,PTPRZ1,GPM6A,TNIK,PRKG1
3.935e-05	-10.14	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	46	16828	48	LIFR,NPAS3,GLIS3,CPE,NRG3,GRIK1,TNIK,GABRB1,SOX6,DTNA,DCLK1,PRKG1,PCDH9,DGKG,ZBTB20,DMD,MYO16,LSAMP,DPP6,CLU,GPM6A,GFAP,PPP2R2B,QKI,CTNNA3,SLC1A3,PHYHIPL,SASH1,PDZRN4,SPON1,GRID2,PTPRZ1,GRIA1,LAMA2,GRIA4,SLC1A2,GABBR2,SMOC1,NTM,PTPRT,HS6ST3,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2
3.986e-05	-10.13	scalp	COSMIC cancer mutations	scalp	2110	17	16828	48	PDZRN4,ATP1A2,PRKG1,DCLK1,PHYHIPL,LAMA2,PPP2R2B,CTNNA3,GFAP,PTPRT,NTM,MYO16,PTPRZ1,GRID2,LSAMP,DMD,GABBR2
4.065e-05	-10.11	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	REACTOME pathways	R-HSA-112314	146	5	10285	28	GRIK1,GRIA4,GABBR2,GABRB1,GRIA1
4.153e-05	-10.09	cell projection morphogenesis	biological process	GO:0048858	496	8	18204	48	LAMA2,PTPRZ1,GPM6A,PRKG1,TNIK,MYO16,DCLK1,CTNND2
4.274e-05	-10.06	Neurotransmitter uptake and Metabolism In Glial Cells	REACTOME pathways	R-HSA-112313	4	2	10285	28	SLC1A2,SLC1A3
4.274e-05	-10.06	Activation of AMPA receptors	REACTOME pathways	R-HSA-399710	4	2	10285	28	GRIA4,GRIA1
4.274e-05	-10.06	Astrocytic Glutamate-Glutamine Uptake And Metabolism	REACTOME pathways	R-HSA-210455	4	2	10285	28	SLC1A2,SLC1A3
4.286e-05	-10.06	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	36	16828	48	SLC1A3,PHYHIPL,HS6ST3,NTRK2,ATP1A2,SASH1,CTNND2,GABBR2,LSAMP,SMOC1,MYO16,CLU,DPP6,PTPRT,QKI,PPP2R2B,CTNNA3,GPM6A,SLC1A2,SOX6,GABRB1,DCLK1,PRKG1,DGKG,PCDH9,SPON1,LIFR,GRID2,PTPRZ1,NRG3,TNIK,GRIA1,GLIS3,CPE,GRIA4,LAMA2
4.287e-05	-10.06	C4-dicarboxylate transport	biological process	GO:0015740	26	3	18204	48	GFAP,SLC1A2,SLC1A3
4.474e-05	-10.01	AMPA glutamate receptor activity	molecular function	GO:0004971	4	2	18094	50	GRIA4,GRIA1
4.550e-05	-10.00	Htt (huntingtin)	protein interactions	15194	77	4	19454	50	NTM,GFAP,LSAMP,GPM6A
4.567e-05	-9.99	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	13	16828	48	CPE,GLIS3,GRIA1,PTPRZ1,GRID2,SMOC1,GABBR2,NPAS3,CTNND2,ATP1A2,DGKG,NTRK2,SPARCL1
4.716e-05	-9.96	Glutamatergic synapse	KEGG pathways	ko04724	114	5	7161	26	GRIA1,GRIA4,GRIK1,SLC1A3,SLC1A2
4.716e-05	-9.96	Glutamatergic synapse	KEGG pathways	hsa04724	114	5	7161	26	GRIK1,SLC1A3,SLC1A2,GRIA1,GRIA4
4.794e-05	-9.95	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	43	16828	48	LIFR,NPAS3,PTPRZ1,GRID2,CPE,GLIS3,GRIA1,GRIK1,TNIK,NRG3,LAMA2,GRIA4,DTNA,GABRB1,SOX6,SLC1A2,PRKG1,DCLK1,PCDH9,DGKG,ZBTB20,DMD,GABBR2,MYO16,SMOC1,LSAMP,CST3,NTM,CLU,DPP6,GPM6B,CTNNA3,QKI,PPP2R2B,GFAP,PTPRT,SLC1A3,HS6ST3,SASH1,ATP1A2,NTRK2,CTNND2,PDZRN4
4.944e-05	-9.91	PLP	smart domains	SM00002	3	2	9717	40	GPM6A,GPM6B
5.002e-05	-9.90	GRIK2 (glutamate ionotropic receptor kainate type subunit 2)	protein interactions	2898	28	3	19454	50	GRIK1,GRIA1,GRID2
5.259e-05	-9.85	dicarboxylic acid transport	biological process	GO:0006835	78	4	18204	48	SLC1A3,NTRK2,GFAP,SLC1A2
5.542e-05	-9.80	MYELINPLP	prints domains	PR00214	3	2	5227	23	GPM6B,GPM6A
5.560e-05	-9.80	nodular	COSMIC cancer mutations	nodular	1515	14	16828	48	CPE,GRIA1,GLIS3,LAMA2,GABBR2,NPAS3,PTPRZ1,GRID2,SMOC1,ATP1A2,DGKG,NTRK2,SPARCL1,CTNND2
5.683e-05	-9.78	positive regulation of synaptic transmission	biological process	GO:0050806	157	5	18204	48	LAMA2,GFAP,GRIA1,NTRK2,SLC1A3
5.822e-05	-9.75	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	19	16828	48	LAMA2,GRIA4,CTNNA3,PPP2R2B,PTPRT,GRIA1,NRG3,PTPRZ1,GRID2,LSAMP,LIFR,DMD,CTNND2,PDZRN4,SASH1,PCDH9,ATP1A2,DCLK1,SLC1A3
5.991e-05	-9.72	regulation of presynaptic membrane potential	biological process	GO:0099505	29	3	18204	48	GABRB1,GRIA1,GRIA4
5.991e-05	-9.72	negative regulation of amyloid-beta formation	biological process	GO:1902430	29	3	18204	48	SPON1,CLU,NTRK2
6.406e-05	-9.66	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	46	16828	48	SLC1A3,PHYHIPL,SASH1,PDZRN4,DMD,MYO16,LSAMP,DPP6,CLU,GPM6A,GPM6B,GFAP,QKI,PPP2R2B,CTNNA3,SOX6,GABRB1,DCLK1,PRKG1,PCDH9,DGKG,ZBTB20,LIFR,NPAS3,GLIS3,CPE,NRG3,GRIK1,TNIK,HS6ST3,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,GABBR2,SMOC1,NTM,PTPRT,SLC1A2,SPON1,GRID2,PTPRZ1,GRIA1,LAMA2,GRIA4
6.554e-05	-9.63	HAX1 (HCLS1 associated protein X-1)	protein interactions	10456	397	7	19454	50	GPM6B,DCLK1,MAPK10,GPM6A,NTM,DPP6,CLU
6.644e-05	-9.62	neurotransmitter uptake	biological process	GO:0001504	30	3	18204	48	ATP1A2,SLC1A3,SLC1A2
6.903e-05	-9.58	presynaptic membrane	cellular component	GO:0042734	168	5	19108	49	SLC1A2,GRIA1,GPM6A,GRIK1,GABRB1
7.047e-05	-9.56	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	6	16828	48	MYO16,PDZRN4,PCDH9,NPAS3,NRG3,GABBR2
7.047e-05	-9.56	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	6	16828	48	PCDH9,GABBR2,NRG3,NPAS3,MYO16,PDZRN4
7.270e-05	-9.53	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	32	16828	48	AQP4,CTNND2,PDZRN4,SPARCL1,SASH1,ATP1A2,MYO16,SMOC1,DMD,GABBR2,GPM6A,CTNNA3,PTPRT,DPP6,PRKG1,DCLK1,SOX6,ZBTB20,PCDH9,PTPRZ1,GRID2,LIFR,SPON1,NPAS3,GRIA4,LAMA2,CPE,GRIA1,GLIS3,GRIK1,TNIK,NRG3
7.343e-05	-9.52	negative regulation of amyloid precursor protein catabolic process	biological process	GO:1902992	31	3	18204	48	SPON1,CLU,NTRK2
7.444e-05	-9.51	high-affinity L-glutamate transmembrane transporter activity	molecular function	GO:0005314	5	2	18094	50	SLC1A3,SLC1A2
7.444e-05	-9.51	glutamate:sodium symporter activity	molecular function	GO:0015501	5	2	18094	50	SLC1A2,SLC1A3
7.459e-05	-9.50	presynaptic active zone membrane	cellular component	GO:0048787	32	3	19108	49	GRIA1,GPM6A,GABRB1
7.526e-05	-9.49	pharynx	COSMIC cancer mutations	pharynx	2696	19	16828	48	NPAS3,MYO16,PTPRZ1,DPP6,GRIA1,CLU,NRG3,LAMA2,PTPRT,QKI,GABRB1,DTNA,SLC1A2,PCDH9,NTRK2,DGKG,ATP1A2,PDZRN4,CTNND2
7.700e-05	-9.47	cell body	cellular component	GO:0044297	556	8	19108	49	GRIA4,GFAP,GRIA1,SLC1A3,CTNND2,SLC1A2,ATP1A2,GPM6A
8.087e-05	-9.42	ligand-gated ion channel signaling pathway	biological process	GO:1990806	32	3	18204	48	GRIK1,GRIA1,GRIA4
8.255e-05	-9.40	NTM (neurotrimin)	protein interactions	50863	33	3	19454	50	NTM,GPM6A,LSAMP
8.683e-05	-9.35	cell communication	biological process	GO:0007154	5010	26	18204	48	TNIK,PRKG1,MAPK10,DTNA,ATP1A2,CPE,PTPRT,DMD,SLC1A3,NTRK2,DCLK1,GABBR2,GRIK1,SPARCL1,GRID2,GRIA1,CTNNA3,CTNND2,MYO16,DGKG,LIFR,CLU,GRIA4,SLC1A2,NRG3,GABRB1
8.752e-05	-9.34	DGUOK (deoxyguanosine kinase)	protein interactions	1716	91	4	19454	50	NTM,GPM6B,DCLK1,GPM6A
9.721e-05	-9.24	negative regulation of amide metabolic process	biological process	GO:0034249	34	3	18204	48	SPON1,CLU,NTRK2
1.014e-04	-9.20	L-aspartate import across plasma membrane	biological process	GO:0140009	6	2	18204	48	SLC1A2,SLC1A3
1.060e-04	-9.15	amyloid-beta binding	molecular function	GO:0001540	89	4	18094	50	CLU,GRIA4,GRIA1,CST3
1.061e-04	-9.15	EF-hand_3	pfam domains	PF09069	6	2	17795	48	DTNA,DMD
1.061e-04	-9.15	EF-hand_2	pfam domains	PF09068	6	2	17795	48	DTNA,DMD
1.064e-04	-9.15	EF-hand_dom_typ2	interpro domains	IPR015154	6	2	18521	50	DMD,DTNA
1.064e-04	-9.15	EF-hand_dom_typ1	interpro domains	IPR015153	6	2	18521	50	DMD,DTNA
1.107e-04	-9.11	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	33	16828	48	HS6ST3,CTNND2,PDZRN4,ATP1A2,SASH1,LSAMP,CST3,MYO16,SMOC1,QKI,PPP2R2B,CTNNA3,PTPRT,GFAP,GPM6A,NTM,DPP6,PRKG1,DCLK1,SLC1A2,DTNA,ZBTB20,DGKG,PCDH9,PTPRZ1,GRID2,SPON1,LAMA2,GRIA4,TNIK,GRIK1,NRG3,GRIA1
1.120e-04	-9.10	transmembrane transporter complex	cellular component	GO:1902495	434	7	19108	49	GRID2,GABRB1,DPP6,GRIA1,GRIK1,GRIA4,ATP1A2
1.145e-04	-9.08	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	14	16828	48	DMD,LIFR,GRID2,PTPRZ1,MYO16,GRIK1,DPP6,CPE,QKI,LAMA2,DTNA,DGKG,PDZRN4,CTNND2
1.145e-04	-9.08	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	14	16828	48	DMD,LIFR,GRID2,PTPRZ1,MYO16,GRIK1,DPP6,CPE,QKI,LAMA2,DTNA,DGKG,PDZRN4,CTNND2
1.158e-04	-9.06	glial cell projection	cellular component	GO:0097386	37	3	19108	49	SLC1A2,GFAP,AQP4
1.161e-04	-9.06	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	43	16828	48	MYO16,SMOC1,CST3,LSAMP,DMD,GABBR2,GPM6B,QKI,CTNNA3,PPP2R2B,PTPRT,GFAP,NTM,DPP6,CLU,HS6ST3,SLC1A3,CTNND2,PDZRN4,SASH1,ATP1A2,NTRK2,PTPRZ1,GRID2,LIFR,NPAS3,GRIA4,LAMA2,CPE,GRIA1,GLIS3,GRIK1,TNIK,NRG3,PRKG1,DCLK1,DTNA,GABRB1,SOX6,SLC1A2,ZBTB20,PCDH9,DGKG
1.176e-04	-9.05	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	24	16828	48	GRIA1,GLIS3,CPE,GRIK1,TNIK,GRIA4,LAMA2,LIFR,GRID2,PTPRZ1,PCDH9,DGKG,DTNA,PRKG1,GPM6B,PTPRT,SMOC1,LSAMP,SPARCL1,SASH1,ATP1A2,AQP4,PDZRN4,CTNND2
1.207e-04	-9.02	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	13	16828	48	PRKG1,HS6ST3,GABRB1,SOX6,PDZRN4,MYO16,GRID2,DMD,GABBR2,LAMA2,PTPRT,CTNNA3,NRG3
1.264e-04	-8.98	plasma membrane signaling receptor complex	cellular component	GO:0098802	191	5	19108	49	GRIK1,GRIA1,GABBR2,GRIA4,GRID2
1.294e-04	-8.95	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	9	18094	50	GABRB1,ATP1A2,GRIK1,SLC1A2,SLC1A3,GRIA1,AQP4,GPM6A,GRIA4
1.306e-04	-8.94	plasma membrane protein complex	cellular component	GO:0098797	600	8	19108	49	GRIA4,GABBR2,ATP1A2,GRID2,DPP6,DMD,GRIA1,GRIK1
1.360e-04	-8.90	amino acid import across plasma membrane	biological process	GO:0089718	38	3	18204	48	SLC1A3,GFAP,SLC1A2
1.402e-04	-8.87	humerus	COSMIC cancer mutations	humerus	546	8	16828	48	PRKG1,GRID2,GABRB1,GPM6A,GRIA4,LAMA2,PPP2R2B,CTNNA3
1.407e-04	-8.87	biliary_tract-gallbladder-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-gallbladder-carcinoma-adenocarcinoma	2821	19	16828	48	DPP6,GRIA1,CLU,NRG3,GRIK1,TNIK,LAMA2,PTPRT,DMD,MYO16,GRID2,PTPRZ1,PCDH9,SASH1,SPARCL1,PDZRN4,CTNND2,DCLK1,PRKG1
1.407e-04	-8.87	gallbladder	COSMIC cancer mutations	gallbladder	2821	19	16828	48	DCLK1,PRKG1,SPARCL1,SASH1,PCDH9,PDZRN4,CTNND2,DMD,GRID2,PTPRZ1,MYO16,NRG3,GRIK1,TNIK,GRIA1,DPP6,CLU,PTPRT,LAMA2
1.483e-04	-8.82	SPARC_Ca_bdg	pfam domains	PF10591	7	2	17795	48	SMOC1,SPARCL1
1.483e-04	-8.82	SDF	pfam domains	PF00375	7	2	17795	48	SLC1A2,SLC1A3
1.487e-04	-8.81	SPARC/Testican_Ca-bd-dom	interpro domains	IPR019577	7	2	18521	50	SPARCL1,SMOC1
1.487e-04	-8.81	Na-dicarboxylate_symporter	interpro domains	IPR001991	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na:dicarbo_symporter_sf	interpro domains	IPR036458	7	2	18521	50	SLC1A2,SLC1A3
1.487e-04	-8.81	Na-dicarboxylate_symporter_CS	interpro domains	IPR018107	7	2	18521	50	SLC1A2,SLC1A3
1.584e-04	-8.75	carboxylic acid transmembrane transporter activity	molecular function	GO:0046943	186	5	18094	50	GRIA1,GRIA4,SLC1A2,SLC1A3,GRIK1
1.584e-04	-8.75	ligand-gated monoatomic ion channel activity	molecular function	GO:0015276	186	5	18094	50	GRIA1,GABRB1,GRIK1,GRID2,GRIA4
1.603e-04	-8.74	cell differentiation	biological process	GO:0030154	3645	21	18204	48	MYO16,SOX6,SMOC1,QKI,CTNND2,GFAP,PTPRZ1,GRID2,GPM6A,NTM,TNIK,PRKG1,GABRB1,DCLK1,NTRK2,CLU,SLC1A3,DMD,LAMA2,GPM6B,DGKG
1.623e-04	-8.73	cellular developmental process	biological process	GO:0048869	3648	21	18204	48	GFAP,PTPRZ1,GRID2,GPM6A,NTM,TNIK,PRKG1,MYO16,SOX6,SMOC1,QKI,CTNND2,DMD,LAMA2,GPM6B,DGKG,GABRB1,DCLK1,NTRK2,CLU,SLC1A3
1.624e-04	-8.73	organic acid transmembrane transporter activity	molecular function	GO:0005342	187	5	18094	50	GRIA4,GRIK1,SLC1A3,SLC1A2,GRIA1
1.624e-04	-8.73	ligand-gated channel activity	molecular function	GO:0022834	187	5	18094	50	GABRB1,GRIA1,GRID2,GRIA4,GRIK1
1.626e-04	-8.72	transporter complex	cellular component	GO:1990351	461	7	19108	49	GRIA4,ATP1A2,DPP6,GABRB1,GRID2,GRIK1,GRIA1
1.709e-04	-8.67	GRIA2 (glutamate ionotropic receptor AMPA type subunit 2)	protein interactions	2891	42	3	19454	50	GRID2,GPM6A,GRIA1
1.729e-04	-8.66	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	4	16828	48	GPM6A,CTNND2,PTPRT,LSAMP
1.795e-04	-8.63	LHB (luteinizing hormone subunit beta)	protein interactions	3972	8	2	19454	50	GFAP,NTM
1.805e-04	-8.62	adenoma	COSMIC cancer mutations	adenoma	2873	19	16828	48	ZBTB20,CTNND2,SASH1,PCDH9,NTRK2,PRKG1,PHYHIPL,GPM6A,LAMA2,GRIA4,PTPRT,CTNNA3,GRIK1,MYO16,GRID2,PTPRZ1,LIFR,NPAS3,GABBR2
1.911e-04	-8.56	monoatomic ion transmembrane transporter activity	molecular function	GO:0015075	752	9	18094	50	GRID2,GPM6A,GRIA4,GRIA1,ATP1A2,GRIK1,SLC1A3,SLC1A2,GABRB1
2.146e-04	-8.45	Sodium:dicarboxylate symporter	gene3d domains	1.10.3860.10	7	2	14470	47	SLC1A2,SLC1A3
2.175e-04	-8.43	monoatomic ion transmembrane transport	biological process	GO:0034220	804	9	18204	48	ATP1A2,SLC1A3,SLC1A2,GABRB1,GRIK1,GRIA4,GPM6A,GRIA1,GRID2
2.259e-04	-8.40	acidic amino acid transport	biological process	GO:0015800	45	3	18204	48	SLC1A2,NTRK2,SLC1A3
2.293e-04	-8.38	astrocyte end-foot	cellular component	GO:0097450	9	2	19108	49	AQP4,GFAP
2.301e-04	-8.38	synapse organization	biological process	GO:0050808	333	6	18204	48	GPM6A,CTNND2,SPARCL1,NRG3,GRIA1,GRID2
2.304e-04	-8.38	NEGR1 (neuronal growth regulator 1)	protein interactions	257194	9	2	19454	50	LSAMP,NTM
2.304e-04	-8.38	LSAMP (limbic system associated membrane protein)	protein interactions	4045	9	2	19454	50	LSAMP,NTM
2.329e-04	-8.36	signaling	biological process	GO:0023052	4968	25	18204	48	DTNA,MAPK10,PRKG1,TNIK,CPE,ATP1A2,DMD,PTPRT,SPARCL1,GRIK1,GABBR2,DCLK1,NTRK2,SLC1A3,GRIA1,GRID2,MYO16,CTNND2,LIFR,DGKG,SLC1A2,GABRB1,NRG3,GRIA4,CLU
2.339e-04	-8.36	human chr11p15.2	chromosome location	human chr11p15.2	12	2	26134	50	SOX6,SPON1
2.339e-04	-8.36	ALB (albumin)	protein interactions	213	342	6	19454	50	PPP2R2B,CST3,GFAP,DMD,PDZRN4,DGKG
2.373e-04	-8.35	monoatomic ion channel complex	cellular component	GO:0034702	344	6	19108	49	GRIA1,GRIK1,GRID2,GABRB1,DPP6,GRIA4
2.392e-04	-8.34	GRIA1 (glutamate ionotropic receptor AMPA type subunit 1)	protein interactions	2890	47	3	19454	50	GRID2,GRIA4,GRIA1
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_2	prosite domains	PS00714	7	2	12186	42	SLC1A3,SLC1A2
2.409e-04	-8.33	NA_DICARBOXYL_SYMP_1	prosite domains	PS00713	7	2	12186	42	SLC1A2,SLC1A3
2.596e-04	-8.26	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	40	16828	48	PRKG1,DCLK1,DTNA,SOX6,GABRB1,DGKG,PCDH9,PTPRZ1,GRID2,SPON1,NPAS3,LIFR,LAMA2,GRIA4,TNIK,GRIK1,NRG3,CPE,GRIA1,HS6ST3,CTNND2,PDZRN4,ATP1A2,NTRK2,SPARCL1,SASH1,CST3,MYO16,SMOC1,GABBR2,DMD,PPP2R2B,QKI,CTNNA3,PTPRT,GPM6B,GPM6A,NTM,CLU,DPP6
2.619e-04	-8.25	synapse assembly	biological process	GO:0007416	118	4	18204	48	GPM6A,NRG3,GRID2,GRIA1
2.635e-04	-8.24	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	40	16828	48	PRKG1,DCLK1,DTNA,SOX6,GABRB1,DGKG,PCDH9,PTPRZ1,GRID2,SPON1,NPAS3,LIFR,LAMA2,GRIA4,GRIK1,TNIK,NRG3,CPE,GRIA1,HS6ST3,CTNND2,PDZRN4,ATP1A2,NTRK2,SASH1,SPARCL1,CST3,MYO16,SMOC1,GABBR2,DMD,PPP2R2B,CTNNA3,QKI,PTPRT,GPM6B,GPM6A,NTM,DPP6,CLU
2.663e-04	-8.23	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	33	16828	48	QKI,GFAP,PTPRT,NTM,CLU,MYO16,LSAMP,CST3,DMD,GABBR2,AQP4,CTNND2,PDZRN4,SASH1,ATP1A2,NTRK2,HS6ST3,GRIA4,LAMA2,GRIA1,GRIK1,NRG3,PTPRZ1,LIFR,SPON1,NPAS3,ZBTB20,PCDH9,DGKG,PRKG1,DCLK1,SOX6,SLC1A2
2.663e-04	-8.23	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	33	16828	48	CLU,NTM,GFAP,PTPRT,QKI,DMD,GABBR2,MYO16,CST3,LSAMP,SASH1,NTRK2,ATP1A2,AQP4,PDZRN4,CTNND2,HS6ST3,GRIA1,NRG3,GRIK1,GRIA4,LAMA2,LIFR,NPAS3,SPON1,PTPRZ1,PCDH9,DGKG,ZBTB20,SOX6,SLC1A2,DCLK1,PRKG1
2.738e-04	-8.20	regulation of amyloid-beta formation	biological process	GO:1902003	48	3	18204	48	SPON1,NTRK2,CLU
2.807e-04	-8.18	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	13	16828	48	PDZRN4,PRKG1,HS6ST3,GABRB1,SOX6,LAMA2,PTPRT,CTNNA3,NRG3,MYO16,GRID2,DMD,GABBR2
2.810e-04	-8.18	membrane protein complex	cellular component	GO:0098796	1261	11	19108	49	GRIK1,GRIA1,GABBR2,DMD,DPP6,GABRB1,GRID2,ATP1A2,SLC1A2,SLC1A3,GRIA4
2.827e-04	-8.17	regulation of biological quality	biological process	GO:0065008	2936	18	18204	48	ATP1A2,QKI,CPE,GPM6A,PRKG1,GFAP,CTNNA3,GRID2,GRIA1,NTRK2,AQP4,CLU,GABRB1,GRIA4,GRIK1,DGKG,DMD,PTPRT
2.879e-04	-8.15	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	33	16828	48	CLU,DPP6,PPP2R2B,QKI,CTNNA3,PTPRT,GPM6A,GABBR2,LSAMP,MYO16,SMOC1,ATP1A2,NTRK2,SASH1,CTNND2,PHYHIPL,SLC1A3,HS6ST3,NRG3,CPE,GRIA1,GLIS3,GRIA4,LAMA2,SPON1,LIFR,GRID2,DGKG,PCDH9,SLC1A2,GABRB1,SOX6,PRKG1
3.023e-04	-8.10	cellular response to brain-derived neurotrophic factor stimulus	biological process	GO:1990416	10	2	18204	48	GRIA1,NTRK2
3.023e-04	-8.10	cellular response to cocaine	biological process	GO:0071314	10	2	18204	48	SLC1A2,SLC1A3
3.023e-04	-8.10	neuronal action potential propagation	biological process	GO:0019227	10	2	18204	48	ATP1A2,NTRK2
3.023e-04	-8.10	action potential propagation	biological process	GO:0098870	10	2	18204	48	ATP1A2,NTRK2
3.165e-04	-8.06	action potential	biological process	GO:0001508	124	4	18204	48	GRIA1,DMD,NTRK2,ATP1A2
3.173e-04	-8.06	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	21	16828	48	HS6ST3,CTNND2,ZBTB20,ATP1A2,DGKG,SPARCL1,PCDH9,SASH1,PTPRZ1,GRID2,MYO16,GABBR2,SPON1,GFAP,PTPRT,GRIA4,LAMA2,GPM6A,TNIK,NRG3,GRIA1
3.199e-04	-8.05	middle_third	COSMIC cancer mutations	middle_third	3533	21	16828	48	SPON1,GABBR2,GRID2,PTPRZ1,MYO16,NRG3,TNIK,GRIA1,PTPRT,GFAP,GPM6A,LAMA2,GRIA4,HS6ST3,DGKG,ATP1A2,SASH1,PCDH9,SPARCL1,CTNND2,ZBTB20
3.342e-04	-8.00	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	16	16828	48	NRG3,GRIK1,GRIA1,CTNNA3,DMD,PTPRZ1,SMOC1,MYO16,NTRK2,DGKG,ATP1A2,PCDH9,CTNND2,ZBTB20,SLC1A2,DCLK1
3.571e-04	-7.94	glial cell development	biological process	GO:0021782	128	4	18204	48	NTRK2,CLU,GPM6B,GFAP
3.571e-04	-7.94	myelination	biological process	GO:0042552	128	4	18204	48	GPM6B,NTRK2,QKI,CLU
3.590e-04	-7.93	transmembrane transport	biological process	GO:0055085	1264	11	18204	48	ATP1A2,AQP4,SLC1A3,SLC1A2,GABRB1,GRIA4,GRIK1,GPM6A,GFAP,GRID2,GRIA1
3.613e-04	-7.93	SYNM (synemin)	protein interactions	23336	54	3	19454	50	PPP2R2B,GFAP,DTNA
3.688e-04	-7.91	L-aspartate transmembrane transport	biological process	GO:0070778	11	2	18204	48	SLC1A3,SLC1A2
3.688e-04	-7.91	L-glutamate import across plasma membrane	biological process	GO:0098712	11	2	18204	48	SLC1A3,SLC1A2
3.724e-04	-7.90	Neuroactive ligand-receptor interaction	KEGG pathways	ko04080	276	6	7161	26	GABRB1,GRIK1,GABBR2,GRID2,GRIA4,GRIA1
3.724e-04	-7.90	Neuroactive ligand-receptor interaction	KEGG pathways	hsa04080	276	6	7161	26	GABRB1,GRIK1,GABBR2,GRID2,GRIA4,GRIA1
3.788e-04	-7.88	axon ensheathment	biological process	GO:0008366	130	4	18204	48	CLU,QKI,NTRK2,GPM6B
3.788e-04	-7.88	ensheathment of neurons	biological process	GO:0007272	130	4	18204	48	QKI,CLU,NTRK2,GPM6B
3.838e-04	-7.87	EDTRNSPORT	prints domains	PR00173	7	2	5227	23	SLC1A3,SLC1A2
3.841e-04	-7.86	Nicotine addiction	KEGG pathways	hsa05033	40	3	7161	26	GABRB1,GRIA4,GRIA1
3.841e-04	-7.86	Nicotine addiction	KEGG pathways	ko05033	40	3	7161	26	GRIA1,GRIA4,GABRB1
3.858e-04	-7.86	SBP_bac_3	pfam domains	PF00497	11	2	17795	48	GRIA1,GRIA4
3.863e-04	-7.86	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	8	16828	48	NTM,PPP2R2B,PDZRN4,PTPRT,GABBR2,PTPRZ1,GRID2,DCLK1
3.868e-04	-7.86	Solute-binding_3/MltF_N	interpro domains	IPR001638	11	2	18521	50	GRIA4,GRIA1
3.986e-04	-7.83	cell surface	cellular component	GO:0009986	896	9	19108	49	DMD,GRIA1,LIFR,SLC1A3,SLC1A2,CLU,ATP1A2,PTPRT,AQP4
4.014e-04	-7.82	amino acid transport	biological process	GO:0006865	132	4	18204	48	SLC1A3,NTRK2,GFAP,SLC1A2
4.099e-04	-7.80	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	3	18204	48	NTRK2,CLU,SPON1
4.099e-04	-7.80	response to cocaine	biological process	GO:0042220	55	3	18204	48	GRIA1,SLC1A2,SLC1A3
4.203e-04	-7.77	OAS2 (2'-5'-oligoadenylate synthetase 2)	protein interactions	4939	12	2	19454	50	PRKG1,SASH1
4.313e-04	-7.75	channel activity	molecular function	GO:0015267	502	7	18094	50	GRID2,GPM6A,GRIA4,GRIA1,AQP4,GRIK1,GABRB1
4.365e-04	-7.74	passive transmembrane transporter activity	molecular function	GO:0022803	503	7	18094	50	GRIA1,AQP4,GRID2,GPM6A,GRIA4,GABRB1,GRIK1
4.391e-04	-7.73	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	4	7161	26	GABRB1,GRIA1,GRIA4,MAPK10
4.391e-04	-7.73	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	4	7161	26	MAPK10,GRIA4,GRIA1,GABRB1
4.405e-04	-7.73	femur	COSMIC cancer mutations	femur	1197	11	16828	48	CTNNA3,GRIA4,LAMA2,NRG3,DPP6,PCDH9,GRID2,HS6ST3,PTPRZ1,GABBR2,SPON1
4.894e-04	-7.62	fn3	pfam domains	PF00041	136	4	17795	48	LIFR,PTPRZ1,PTPRT,PHYHIPL
5.030e-04	-7.59	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	33	16828	48	CST3,MYO16,SMOC1,GABBR2,DMD,PPP2R2B,QKI,CTNNA3,PTPRT,GPM6B,SLC1A3,CTNND2,PDZRN4,ATP1A2,NTRK2,SPARCL1,SASH1,PTPRZ1,GRID2,NPAS3,LIFR,GRIA4,LAMA2,TNIK,NRG3,GRIA1,GLIS3,PRKG1,DCLK1,DTNA,SOX6,ZBTB20,DGKG
5.290e-04	-7.54	neuron migration	biological process	GO:0001764	142	4	18204	48	PRKG1,GPM6A,NTRK2,DCLK1
5.298e-04	-7.54	transmission of nerve impulse	biological process	GO:0019226	60	3	18204	48	GRIA1,NTRK2,ATP1A2
5.393e-04	-7.53	skin-ear-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-ear-carcinoma-squamous_cell_carcinoma	506	7	16828	48	NPAS3,LIFR,SPARCL1,GABRB1,PRKG1,LAMA2,ZBTB20
5.776e-04	-7.46	PLXNA4 (plexin A4)	protein interactions	91584	14	2	19454	50	CLU,GPM6A
5.806e-04	-7.45	presynapse	cellular component	GO:0098793	569	7	19108	49	GPM6A,SLC1A2,TNIK,GABRB1,NTRK2,GRIK1,GRIA1
6.084e-04	-7.40	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	17	16828	48	DCLK1,SOX6,SLC1A2,ZBTB20,CTNND2,PCDH9,DGKG,NTRK2,ATP1A2,SMOC1,MYO16,PTPRZ1,DMD,CTNNA3,GRIA1,NRG3,GRIK1
6.171e-04	-7.39	Amyotrophic lateral sclerosis (ALS)	WikiPathways	WP2447	38	3	5310	24	CST3,SLC1A2,GRIA1
6.172e-04	-7.39	animal organ development	biological process	GO:0048513	2846	17	18204	48	DMD,LAMA2,DCLK1,NTRK2,SLC1A2,NRG3,GPM6A,PRKG1,GRIA1,GRID2,ATP1A2,CSMD1,MYO16,PCDH9,CPE,SOX6,SMOC1
6.190e-04	-7.39	excitatory synapse	cellular component	GO:0060076	65	3	19108	49	GRID2,GPM6A,GRIA1
6.294e-04	-7.37	cAMP signaling pathway	KEGG pathways	hsa04024	198	5	7161	26	GABBR2,MAPK10,ATP1A2,GRIA1,GRIA4
6.294e-04	-7.37	cAMP signaling pathway	KEGG pathways	ko04024	198	5	7161	26	ATP1A2,GRIA1,GRIA4,MAPK10,GABBR2
6.409e-04	-7.35	EF-hand-dom_pair	interpro domains	IPR011992	258	5	18521	50	DGKG,DMD,SPARCL1,SMOC1,DTNA
6.451e-04	-7.35	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	41	16828	48	GABBR2,DMD,LSAMP,MYO16,SMOC1,CLU,DPP6,PPP2R2B,QKI,CTNNA3,GFAP,PTPRT,GPM6A,PHYHIPL,SLC1A3,HS6ST3,ATP1A2,NTRK2,SPARCL1,SASH1,CTNND2,PDZRN4,AQP4,SPON1,NPAS3,PTPRZ1,GRID2,TNIK,NRG3,CPE,GRIA1,GRIA4,LAMA2,SLC1A2,DTNA,SOX6,GABRB1,PRKG1,DGKG,PCDH9,ZBTB20
6.532e-04	-7.33	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	46	16828	48	DMD,LSAMP,CST3,MYO16,CLU,DPP6,GFAP,QKI,CTNNA3,PPP2R2B,GPM6A,SLC1A3,PHYHIPL,SASH1,PDZRN4,NPAS3,LIFR,NRG3,GRIK1,TNIK,GLIS3,CPE,SOX6,GABRB1,DCLK1,PRKG1,DGKG,PCDH9,ZBTB20,GABBR2,SMOC1,NTM,PTPRT,HS6ST3,NTRK2,ATP1A2,SPARCL1,CTNND2,AQP4,SPON1,GRID2,PTPRZ1,GRIA1,LAMA2,GRIA4,SLC1A2
6.612e-04	-7.32	cellular response to stimulus	biological process	GO:0051716	6307	28	18204	48	CPE,ATP1A2,ZBTB20,DTNA,GFAP,MAPK10,PRKG1,TNIK,SPARCL1,GRIK1,GABBR2,DCLK1,NTRK2,SLC1A3,DMD,PTPRT,MYO16,CTNND2,GRIA1,GRID2,SLC1A2,GABRB1,NRG3,GRIA4,CLU,AQP4,LIFR,DGKG
6.654e-04	-7.32	RNASE13 (ribonuclease A family member 13 (inactive))	protein interactions	440163	15	2	19454	50	CLU,CPE
6.667e-04	-7.31	L-glutamate transmembrane transporter activity	molecular function	GO:0005313	14	2	18094	50	SLC1A2,SLC1A3
6.700e-04	-7.31	long-term synaptic potentiation	biological process	GO:0060291	65	3	18204	48	GRIA1,GFAP,NTRK2
6.935e-04	-7.27	cell adhesion	biological process	GO:0007155	942	9	18204	48	LSAMP,CTNNA3,SPON1,GRID2,PTPRT,NTM,PCDH9,SPARCL1,CTNND2
7.118e-04	-7.25	plasma membrane bounded cell projection organization	biological process	GO:0120036	1152	10	18204	48	PRKG1,TNIK,GPM6A,PTPRZ1,GFAP,GPM6B,LAMA2,CTNND2,DCLK1,MYO16
7.412e-04	-7.21	response to stimulus	biological process	GO:0050896	7803	32	18204	48	CTNND2,CSMD1,MYO16,GPM6A,GRID2,CST3,GRIA1,AQP4,CLU,NRG3,GABRB1,SLC1A2,GRIA4,DGKG,LIFR,ATP1A2,ZBTB20,CPE,SOX6,PRKG1,TNIK,GFAP,DTNA,MAPK10,DCLK1,NTRK2,SLC1A3,SPARCL1,GABBR2,GRIK1,DMD,PTPRT
7.549e-04	-7.19	collagen-containing extracellular matrix	cellular component	GO:0062023	428	6	19108	49	PTPRZ1,CLU,SPON1,SMOC1,SPARCL1,LAMA2
7.555e-04	-7.19	postsynaptic density, intracellular component	cellular component	GO:0099092	16	2	19108	49	GRIA1,TNIK
7.765e-04	-7.16	learning or memory	biological process	GO:0007611	276	5	18204	48	NTRK2,ATP1A2,CSMD1,PTPRZ1,GRIA1
7.765e-04	-7.16	telencephalon development	biological process	GO:0021537	276	5	18204	48	NTRK2,ATP1A2,SLC1A2,NRG3,GRIA1
7.844e-04	-7.15	transmembrane transporter activity	molecular function	GO:0022857	1110	10	18094	50	SLC1A3,SLC1A2,GRIK1,ATP1A2,GABRB1,GRIA4,GPM6A,GRID2,GRIA1,AQP4
8.086e-04	-7.12	human chr3q13.31	chromosome location	human chr3q13.31	22	2	26134	50	LSAMP,ZBTB20
8.180e-04	-7.11	monoatomic ion transport	biological process	GO:0006811	964	9	18204	48	GPM6A,GRIA1,GRID2,ATP1A2,SLC1A3,GABRB1,SLC1A2,GRIK1,GRIA4
8.442e-04	-7.08	organic anion transmembrane transporter activity	molecular function	GO:0008514	268	5	18094	50	GRIK1,SLC1A2,SLC1A3,GRIA4,GRIA1
9.039e-04	-7.01	cell-cell contact zone	cellular component	GO:0044291	74	3	19108	49	ATP1A2,PCDH9,CTNNA3
9.282e-04	-6.98	import across plasma membrane	biological process	GO:0098739	165	4	18204	48	SLC1A3,ATP1A2,SLC1A2,GFAP
9.401e-04	-6.97	peptide metabolic process	biological process	GO:0006518	73	3	18204	48	DMD,CPE,SLC1A2
9.431e-04	-6.97	sodium ion transmembrane transporter activity	molecular function	GO:0015081	158	4	18094	50	SLC1A3,SLC1A2,ATP1A2,GRIK1
9.442e-04	-6.97	ZZ	pfam domains	PF00569	17	2	17795	48	DTNA,DMD
9.478e-04	-6.96	Unblocking of NMDA receptor, glutamate binding and activation	REACTOME pathways	R-HSA-438066	17	2	10285	28	GRIA1,GRIA4
9.478e-04	-6.96	Trafficking of GluR2-containing AMPA receptors	REACTOME pathways	R-HSA-416993	17	2	10285	28	GRIA4,GRIA1
9.648e-04	-6.94	GRIK5 (glutamate ionotropic receptor kainate type subunit 5)	protein interactions	2901	18	2	19454	50	GRIK1,GRID2
9.755e-04	-6.93	cell projection organization	biological process	GO:0030030	1200	10	18204	48	GPM6A,PRKG1,TNIK,GFAP,GPM6B,LAMA2,PTPRZ1,DCLK1,CTNND2,MYO16
9.780e-04	-6.93	positive regulation of gliogenesis	biological process	GO:0014015	74	3	18204	48	QKI,PTPRZ1,GFAP
9.830e-04	-6.92	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	40	16828	48	SASH1,ATP1A2,NTRK2,CTNND2,PDZRN4,SLC1A3,HS6ST3,NTM,DPP6,GPM6B,GPM6A,PPP2R2B,CTNNA3,GFAP,PTPRT,DMD,GABBR2,MYO16,SMOC1,LSAMP,PCDH9,DGKG,ZBTB20,DTNA,GABRB1,SLC1A2,PRKG1,DCLK1,CPE,GLIS3,TNIK,GRIK1,NRG3,LAMA2,GRIA4,LIFR,SPON1,NPAS3,PTPRZ1,GRID2
9.830e-04	-6.92	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	40	16828	48	LIFR,SPON1,NPAS3,PTPRZ1,GRID2,CPE,GLIS3,TNIK,GRIK1,NRG3,LAMA2,GRIA4,DTNA,GABRB1,SLC1A2,PRKG1,DCLK1,PCDH9,DGKG,ZBTB20,DMD,GABBR2,MYO16,SMOC1,LSAMP,NTM,DPP6,GPM6B,GPM6A,PPP2R2B,CTNNA3,GFAP,PTPRT,SLC1A3,HS6ST3,SASH1,ATP1A2,NTRK2,CTNND2,PDZRN4
9.912e-04	-6.92	transmembrane receptor protein phosphatase activity	molecular function	GO:0019198	17	2	18094	50	PTPRT,PTPRZ1
9.912e-04	-6.92	transmembrane receptor protein tyrosine phosphatase activity	molecular function	GO:0005001	17	2	18094	50	PTPRZ1,PTPRT
1.015e-03	-6.89	regulation of muscle contraction	biological process	GO:0006937	169	4	18204	48	ATP1A2,PRKG1,CTNNA3,DMD
1.037e-03	-6.87	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	6	18204	48	LAMA2,PTPRZ1,DCLK1,SLC1A3,PRKG1,CTNND2
1.062e-03	-6.85	positive regulation of nervous system development	biological process	GO:0051962	296	5	18204	48	NTRK2,QKI,GFAP,PTPRZ1,GRID2
1.067e-03	-6.84	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	14	16828	48	PCDH9,SPARCL1,ATP1A2,CTNND2,GABRB1,DCLK1,CPE,GRIA1,NRG3,LAMA2,CTNNA3,PPP2R2B,LIFR,GRID2
1.067e-03	-6.84	mucosal	COSMIC cancer mutations	mucosal	2009	14	16828	48	SPARCL1,PCDH9,CPE,GRIA1,ATP1A2,NRG3,LAMA2,CTNNA3,CTNND2,PPP2R2B,LIFR,GABRB1,DCLK1,GRID2
1.070e-03	-6.84	adenoid_cystic_carcinoma	COSMIC cancer mutations	adenoid_cystic_carcinoma	1123	10	16828	48	GPM6B,CTNND2,TNIK,NTRK2,PRKG1,MYO16,DCLK1,LIFR,GABRB1,SOX6
1.071e-03	-6.84	postsynaptic specialization, intracellular component	cellular component	GO:0099091	19	2	19108	49	TNIK,GRIA1
1.071e-03	-6.84	parallel fiber to Purkinje cell synapse	cellular component	GO:0098688	19	2	19108	49	GPM6A,GRID2
1.077e-03	-6.83	PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like)	protein interactions	84457	19	2	19454	50	PHYHIPL,GPM6A
1.080e-03	-6.83	prostate	COSMIC cancer mutations	prostate	13883	47	16828	48	NPAS3,LIFR,TNIK,GRIK1,NRG3,CPE,GLIS3,PRKG1,DCLK1,DTNA,SOX6,GABRB1,ZBTB20,DGKG,PCDH9,LSAMP,MYO16,DMD,CTNNA3,PPP2R2B,QKI,GFAP,GPM6B,GPM6A,DPP6,CLU,PHYHIPL,SLC1A3,PDZRN4,SASH1,PTPRZ1,GRID2,SPON1,GRIA4,LAMA2,GRIA1,SLC1A2,SMOC1,GABBR2,PTPRT,NTM,HS6ST3,CTNND2,AQP4,ATP1A2,NTRK2,SPARCL1
1.093e-03	-6.82	presynaptic active zone	cellular component	GO:0048786	79	3	19108	49	GABRB1,GPM6A,GRIA1
1.101e-03	-6.81	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	40	16828	48	GABBR2,DMD,LSAMP,MYO16,SMOC1,NTM,DPP6,CTNNA3,QKI,PPP2R2B,PTPRT,GFAP,SLC1A3,HS6ST3,ATP1A2,NTRK2,SPARCL1,SASH1,CTNND2,PDZRN4,SPON1,NPAS3,LIFR,PTPRZ1,GRID2,TNIK,GRIK1,NRG3,CPE,GRIA1,GLIS3,GRIA4,LAMA2,SLC1A2,SOX6,GABRB1,PRKG1,DCLK1,DGKG,PCDH9
1.101e-03	-6.81	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	40	16828	48	NRG3,GRIK1,TNIK,GRIA1,GLIS3,CPE,GRIA4,LAMA2,NPAS3,SPON1,LIFR,GRID2,PTPRZ1,DGKG,PCDH9,SLC1A2,SOX6,GABRB1,DCLK1,PRKG1,DPP6,NTM,PTPRT,GFAP,QKI,PPP2R2B,CTNNA3,GABBR2,DMD,LSAMP,SMOC1,MYO16,NTRK2,ATP1A2,SASH1,SPARCL1,PDZRN4,CTNND2,SLC1A3,HS6ST3
1.107e-03	-6.81	inorganic cation transmembrane transporter activity	molecular function	GO:0022890	589	7	18094	50	SLC1A3,SLC1A2,ATP1A2,GRIK1,GRIA1,GRIA4,GPM6A
1.113e-03	-6.80	acidic amino acid transmembrane transporter activity	molecular function	GO:0015172	18	2	18094	50	SLC1A3,SLC1A2
1.113e-03	-6.80	behavior	biological process	GO:0007610	619	7	18204	48	CSMD1,SLC1A3,ATP1A2,NTRK2,SLC1A2,GRIA1,PTPRZ1
1.137e-03	-6.78	Dopaminergic synapse	KEGG pathways	hsa04728	130	4	7161	26	MAPK10,PPP2R2B,GRIA4,GRIA1
1.137e-03	-6.78	Dopaminergic synapse	KEGG pathways	ko04728	130	4	7161	26	PPP2R2B,MAPK10,GRIA4,GRIA1
1.139e-03	-6.78	regulation of cardiac muscle contraction	biological process	GO:0055117	78	3	18204	48	ATP1A2,CTNNA3,DMD
1.143e-03	-6.77	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	748	8	16828	48	NTRK2,CTNND2,DTNA,DMD,SOX6,SLC1A3,PRKG1,GRID2
1.179e-03	-6.74	central nervous system neuron differentiation	biological process	GO:0021953	176	4	18204	48	NTRK2,DCLK1,GRID2,GABRB1
1.184e-03	-6.74	GRIP1 (glutamate receptor interacting protein 1)	protein interactions	23426	81	3	19454	50	GRIK1,GRIA4,GRIA1
1.186e-03	-6.74	Znf_ZZ	interpro domains	IPR000433	19	2	18521	50	DTNA,DMD
1.186e-03	-6.74	Znf_ZZ_sf	interpro domains	IPR043145	19	2	18521	50	DMD,DTNA
1.192e-03	-6.73	salivary_gland	COSMIC cancer mutations	salivary_gland	1139	10	16828	48	NTRK2,TNIK,CTNND2,GPM6B,GABRB1,SOX6,LIFR,DCLK1,PRKG1,MYO16
1.194e-03	-6.73	PDZD2 (PDZ domain containing 2)	protein interactions	23037	20	2	19454	50	CST3,CTNND2
1.224e-03	-6.71	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	43	16828	48	GRIA4,LAMA2,CPE,GRIA1,GLIS3,GRIK1,TNIK,NRG3,PTPRZ1,GRID2,LIFR,SPON1,NPAS3,ZBTB20,PCDH9,DGKG,PRKG1,DCLK1,DTNA,SOX6,GABRB1,SLC1A2,GPM6B,GPM6A,QKI,CTNNA3,PPP2R2B,PTPRT,NTM,DPP6,MYO16,LSAMP,CST3,DMD,GABBR2,CTNND2,PDZRN4,SASH1,SPARCL1,ATP1A2,NTRK2,PHYHIPL,SLC1A3
1.238e-03	-6.69	cervix	COSMIC cancer mutations	cervix	11793	43	16828	48	CTNND2,PDZRN4,ATP1A2,NTRK2,SASH1,SPARCL1,PHYHIPL,SLC1A3,PPP2R2B,QKI,CTNNA3,PTPRT,GPM6B,GPM6A,NTM,DPP6,CST3,LSAMP,MYO16,GABBR2,DMD,ZBTB20,DGKG,PCDH9,PRKG1,DCLK1,SLC1A2,DTNA,GABRB1,SOX6,GRIA4,LAMA2,TNIK,GRIK1,NRG3,CPE,GRIA1,GLIS3,PTPRZ1,GRID2,SPON1,NPAS3,LIFR
1.268e-03	-6.67	Long-term depression	KEGG pathways	hsa04730	60	3	7161	26	GRID2,PRKG1,GRIA1
1.268e-03	-6.67	Long-term depression	KEGG pathways	ko04730	60	3	7161	26	GRIA1,GRID2,PRKG1
1.271e-03	-6.67	regulation of amide metabolic process	biological process	GO:0034248	81	3	18204	48	CLU,NTRK2,SPON1
1.299e-03	-6.65	monoatomic ion channel activity	molecular function	GO:0005216	441	6	18094	50	GRIA1,GRIA4,GRID2,GPM6A,GABRB1,GRIK1
1.311e-03	-6.64	GABA receptor complex	cellular component	GO:1902710	21	2	19108	49	GABBR2,GABRB1
1.314e-03	-6.63	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	6	18094	50	GRIA1,GPM6A,ATP1A2,GRIK1,SLC1A2,SLC1A3
1.332e-03	-6.62	-	gene3d domains	1.10.287.70	148	4	14470	47	GRIA4,GRID2,GRIA1,GRIK1
1.394e-03	-6.58	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	12	16828	48	LAMA2,CTNNA3,GFAP,PTPRT,ATP1A2,PRKG1,MYO16,DCLK1,PTPRZ1,LSAMP,DMD,PHYHIPL
1.444e-03	-6.54	CTNNA1 (catenin alpha 1)	protein interactions	1495	325	5	19454	50	CTNNA3,DMD,TNIK,DTNA,SASH1
1.447e-03	-6.54	CYSLTR2 (cysteinyl leukotriene receptor 2)	protein interactions	57105	22	2	19454	50	PCDH9,GRIK1
1.454e-03	-6.53	SALM protein interactions at the synapses	REACTOME pathways	R-HSA-8849932	21	2	10285	28	GRIA4,GRIA1
1.479e-03	-6.52	cognition	biological process	GO:0050890	319	5	18204	48	GRIA1,PTPRZ1,CSMD1,NTRK2,ATP1A2
1.499e-03	-6.50	neuronal cell body	cellular component	GO:0043025	489	6	19108	49	GRIA4,GPM6A,ATP1A2,SLC1A3,CTNND2,GRIA1
1.510e-03	-6.50	vascular transport	biological process	GO:0010232	86	3	18204	48	SLC1A2,SLC1A3,ATP1A2
1.510e-03	-6.50	central nervous system neuron development	biological process	GO:0021954	86	3	18204	48	NTRK2,DCLK1,GABRB1
1.510e-03	-6.50	transport across blood-brain barrier	biological process	GO:0150104	86	3	18204	48	ATP1A2,SLC1A3,SLC1A2
1.521e-03	-6.49	intracellular sodium ion homeostasis	biological process	GO:0006883	22	2	18204	48	ATP1A2,SLC1A3
1.521e-03	-6.49	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	biological process	GO:0010881	22	2	18204	48	DMD,ATP1A2
1.521e-03	-6.49	negative regulation of muscle contraction	biological process	GO:0045932	22	2	18204	48	PRKG1,ATP1A2
1.524e-03	-6.49	transporter activity	molecular function	GO:0005215	1211	10	18094	50	GPM6A,GRID2,GRIA4,GRIA1,AQP4,ATP1A2,GRIK1,SLC1A3,SLC1A2,GABRB1
1.663e-03	-6.40	relaxation of muscle	biological process	GO:0090075	23	2	18204	48	ATP1A2,PRKG1
1.669e-03	-6.40	GABA receptor activity	molecular function	GO:0016917	22	2	18094	50	GABBR2,GABRB1
1.705e-03	-6.37	-	gene3d domains	3.30.60.90	19	2	14470	47	DMD,DTNA
1.713e-03	-6.37	ZF_ZZ_1	prosite domains	PS01357	18	2	12186	42	DTNA,DMD
1.723e-03	-6.36	SNTG2 (syntrophin gamma 2)	protein interactions	54221	24	2	19454	50	DMD,DTNA
1.729e-03	-6.36	PDZ domain binding	molecular function	GO:0030165	86	3	18094	50	GRIA1,DTNA,GRID2
1.742e-03	-6.35	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	COSMIC cancer mutations	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	181	4	16828	48	NPAS3,PPP2R2B,PDZRN4,GRID2
1.757e-03	-6.34	TIAM1 (TIAM Rac1 associated GEF 1)	protein interactions	7074	201	4	19454	50	DCLK1,DTNA,ATP1A2,DMD
1.763e-03	-6.34	signal transduction	biological process	GO:0007165	4637	22	18204	48	NTRK2,DCLK1,SPARCL1,GABBR2,GRIK1,DMD,PTPRT,ATP1A2,CPE,PRKG1,TNIK,DTNA,MAPK10,CLU,NRG3,GRIA4,DGKG,LIFR,CTNND2,MYO16,GRID2,GRIA1
1.777e-03	-6.33	WNT_subtype	COSMIC cancer mutations	WNT_subtype	182	4	16828	48	GRID2,PDZRN4,PPP2R2B,NPAS3
1.791e-03	-6.32	regulation of cellular process	biological process	GO:0050794	11468	40	18204	48	GPM6B,DMD,PTPRT,DCLK1,NTRK2,NPAS3,SLC1A3,SPARCL1,GABBR2,GRIK1,TNIK,PRKG1,DTNA,GFAP,SASH1,MAPK10,ATP1A2,ZBTB20,SOX6,CPE,DPP6,DGKG,LAMA2,LIFR,CLU,GLIS3,SLC1A2,NRG3,GRIA4,GPM6A,SPON1,CTNNA3,PTPRZ1,CST3,GRID2,GRIA1,CTNND2,QKI,MYO16,SMOC1
1.820e-03	-6.31	EF-hand	gene3d domains	1.10.238.10	272	5	14470	47	DGKG,SMOC1,DTNA,SPARCL1,DMD
1.824e-03	-6.31	amino acid:sodium symporter activity	molecular function	GO:0005283	23	2	18094	50	SLC1A2,SLC1A3
1.829e-03	-6.30	ear	COSMIC cancer mutations	ear	624	7	16828	48	NPAS3,GABRB1,LIFR,SPARCL1,ZBTB20,LAMA2,PRKG1
1.852e-03	-6.29	gated channel activity	molecular function	GO:0022836	320	5	18094	50	GRID2,GRIA4,GRIK1,GABRB1,GRIA1
1.870e-03	-6.28	TNC (tenascin C)	protein interactions	3371	25	2	19454	50	SMOC1,CLU
1.891e-03	-6.27	ovary	COSMIC cancer mutations	ovary	14770	48	16828	48	PTPRT,NTM,SMOC1,GABBR2,CTNND2,AQP4,NTRK2,ATP1A2,SPARCL1,HS6ST3,GRIA4,LAMA2,GRIA1,GRID2,PTPRZ1,SPON1,SLC1A2,GFAP,CTNNA3,PPP2R2B,QKI,GPM6A,GPM6B,DPP6,CLU,LSAMP,CST3,MYO16,DMD,PDZRN4,SASH1,SLC1A3,PHYHIPL,NRG3,TNIK,GRIK1,GLIS3,CPE,NPAS3,LIFR,ZBTB20,DGKG,PCDH9,DCLK1,PRKG1,GABRB1,SOX6,DTNA
1.901e-03	-6.27	Glutamate Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-210500	24	2	10285	28	SLC1A3,SLC1A2
1.911e-03	-6.26	ZF_ZZ_2	prosite domains	PS50135	19	2	12186	42	DTNA,DMD
1.912e-03	-6.26	ZnF_ZZ	smart domains	SM00291	16	2	9717	40	DTNA,DMD
1.913e-03	-6.26	human chr10q11.23-q21.1	chromosome location	human chr10q11.23-q21.1	1	1	26134	50	PRKG1
1.913e-03	-6.26	human chr20q12-q13.11	chromosome location	human chr20q12-q13.11	1	1	26134	50	PTPRT
1.913e-03	-6.26	human chrXp21.2-p21.1	chromosome location	human chrXp21.2-p21.1	1	1	26134	50	DMD
1.913e-03	-6.26	human chr3q26.2-q26.31	chromosome location	human chr3q26.2-q26.31	1	1	26134	50	TNIK
1.913e-03	-6.26	human chr6q24.3-q25.1	chromosome location	human chr6q24.3-q25.1	1	1	26134	50	SASH1
1.913e-03	-6.26	human chr3q27.2-q27.3	chromosome location	human chr3q27.2-q27.3	1	1	26134	50	DGKG
1.913e-03	-6.26	human chr4q22.1-q22.2	chromosome location	human chr4q22.1-q22.2	1	1	26134	50	GRID2
1.929e-03	-6.25	HOMER1 (homer scaffold protein 1)	protein interactions	9456	96	3	19454	50	TNIK,GRIK1,GRIA1
1.942e-03	-6.24	transmembrane signaling receptor activity	molecular function	GO:0004888	1251	10	18094	50	GRIA4,GRID2,PTPRT,PTPRZ1,GRIA1,GABBR2,GRIK1,LIFR,GABRB1,NTRK2
1.965e-03	-6.23	L-glutamate transmembrane transport	biological process	GO:0015813	25	2	18204	48	SLC1A3,SLC1A2
1.965e-03	-6.23	positive regulation of amyloid precursor protein catabolic process	biological process	GO:1902993	25	2	18204	48	SPON1,CLU
1.965e-03	-6.23	peptide biosynthetic process	biological process	GO:0043043	25	2	18204	48	DMD,SLC1A2
1.998e-03	-6.22	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	48	DGKG,PCDH9,ZBTB20,DTNA,SOX6,GABRB1,PRKG1,DCLK1,TNIK,GRIK1,NRG3,CPE,GLIS3,NPAS3,LIFR,SASH1,PDZRN4,PHYHIPL,SLC1A3,DPP6,CLU,CTNNA3,QKI,PPP2R2B,GFAP,GPM6B,GPM6A,DMD,CST3,LSAMP,MYO16,SLC1A2,GRIA1,GRIA4,LAMA2,SPON1,PTPRZ1,GRID2,ATP1A2,NTRK2,SPARCL1,CTNND2,AQP4,HS6ST3,NTM,PTPRT,GABBR2,SMOC1
2.013e-03	-6.21	AMPA glutamate receptor complex	cellular component	GO:0032281	26	2	19108	49	GRIA1,GRIA4
2.048e-03	-6.19	endometrium-carcinoma-serous_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-serous_carcinoma	1442	11	16828	48	MYO16,LSAMP,DMD,GRIA4,CTNNA3,PTPRT,DPP6,GRIA1,TNIK,GABRB1,CTNND2
2.055e-03	-6.19	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	41	16828	48	HS6ST3,SLC1A3,PDZRN4,CTNND2,SASH1,SPARCL1,NTRK2,ATP1A2,SMOC1,MYO16,LSAMP,DMD,GABBR2,PTPRT,GFAP,CTNNA3,QKI,PPP2R2B,DPP6,NTM,DCLK1,PRKG1,SOX6,GABRB1,DTNA,SLC1A2,PCDH9,DGKG,GRID2,PTPRZ1,LIFR,NPAS3,SPON1,GRIA4,LAMA2,GLIS3,GRIA1,CPE,NRG3,GRIK1,TNIK
2.063e-03	-6.18	Nuclear signaling by ERBB4	REACTOME pathways	R-HSA-1251985	25	2	10285	28	GFAP,NRG3
2.085e-03	-6.17	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	48	GABRB1,SOX6,DTNA,DCLK1,PRKG1,PCDH9,DGKG,ZBTB20,LIFR,NPAS3,GLIS3,CPE,NRG3,GRIK1,TNIK,SLC1A3,PHYHIPL,SASH1,PDZRN4,DMD,MYO16,LSAMP,CST3,DPP6,CLU,GPM6A,GPM6B,GFAP,QKI,CTNNA3,PPP2R2B,SLC1A2,SPON1,GRID2,PTPRZ1,GRIA1,LAMA2,GRIA4,HS6ST3,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,GABBR2,SMOC1,NTM,PTPRT
2.085e-03	-6.17	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	48	SLC1A2,GRIA1,LAMA2,GRIA4,SPON1,PTPRZ1,GRID2,ATP1A2,NTRK2,SPARCL1,CTNND2,AQP4,HS6ST3,NTM,PTPRT,GABBR2,SMOC1,DGKG,PCDH9,ZBTB20,DTNA,GABRB1,SOX6,PRKG1,DCLK1,TNIK,GRIK1,NRG3,CPE,GLIS3,NPAS3,LIFR,SASH1,PDZRN4,PHYHIPL,SLC1A3,CLU,DPP6,QKI,PPP2R2B,CTNNA3,GFAP,GPM6B,GPM6A,DMD,CST3,LSAMP,MYO16
2.125e-03	-6.15	central nervous system myelination	biological process	GO:0022010	26	2	18204	48	CLU,GPM6B
2.125e-03	-6.15	axon ensheathment in central nervous system	biological process	GO:0032291	26	2	18204	48	GPM6B,CLU
2.132e-03	-6.15	amino acid transmembrane transport	biological process	GO:0003333	97	3	18204	48	SLC1A3,GFAP,SLC1A2
2.147e-03	-6.14	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	KEGG pathways	ko05412	72	3	7161	26	DMD,CTNNA3,LAMA2
2.147e-03	-6.14	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	KEGG pathways	hsa05412	72	3	7161	26	DMD,LAMA2,CTNNA3
2.176e-03	-6.13	FN3_dom	interpro domains	IPR003961	203	4	18521	50	LIFR,PTPRT,PHYHIPL,PTPRZ1
2.176e-03	-6.13	FN3_sf	interpro domains	IPR036116	203	4	18521	50	PTPRT,LIFR,PTPRZ1,PHYHIPL
2.181e-03	-6.13	KCNJ12 (potassium inwardly rectifying channel subfamily J member 12)	protein interactions	3768	27	2	19454	50	DMD,DTNA
2.181e-03	-6.13	HPCAL4 (hippocalcin like 4)	protein interactions	51440	27	2	19454	50	GPM6A,AQP4
2.241e-03	-6.10	biological regulation	biological process	GO:0065007	12501	42	18204	48	PTPRT,DMD,GPM6B,GRIK1,GABBR2,SPARCL1,NPAS3,SLC1A3,NTRK2,DCLK1,MAPK10,SASH1,GFAP,DTNA,PRKG1,TNIK,DPP6,SOX6,CPE,ZBTB20,ATP1A2,LIFR,LAMA2,DGKG,GRIA4,GABRB1,NRG3,SLC1A2,CLU,GLIS3,AQP4,GRIA1,GRID2,PTPRZ1,CST3,SPON1,CTNNA3,GPM6A,SMOC1,MYO16,QKI,CTNND2
2.253e-03	-6.10	breast-carcinoma-ductal_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductal_carcinoma	14824	48	16828	48	SLC1A2,GRIA1,GRIA4,LAMA2,SPON1,GRID2,PTPRZ1,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,HS6ST3,NTM,PTPRT,GABBR2,SMOC1,PCDH9,DGKG,ZBTB20,SOX6,GABRB1,DTNA,DCLK1,PRKG1,GLIS3,CPE,NRG3,GRIK1,TNIK,LIFR,NPAS3,SASH1,PDZRN4,SLC1A3,PHYHIPL,DPP6,CLU,GPM6A,GPM6B,GFAP,PPP2R2B,CTNNA3,QKI,DMD,MYO16,CST3,LSAMP
2.260e-03	-6.09	regulation of striated muscle contraction	biological process	GO:0006942	99	3	18204	48	ATP1A2,DMD,CTNNA3
2.260e-03	-6.09	regulation of neurotransmitter transport	biological process	GO:0051588	99	3	18204	48	GFAP,GPM6B,ATP1A2
2.291e-03	-6.08	regulation of cardiac muscle contraction by calcium ion signaling	biological process	GO:0010882	27	2	18204	48	ATP1A2,DMD
2.325e-03	-6.06	response to alkaloid	biological process	GO:0043279	100	3	18204	48	GRIA1,SLC1A2,SLC1A3
2.397e-03	-6.03	other	COSMIC cancer mutations	other	14843	48	16828	48	SPON1,GRID2,PTPRZ1,GRIA1,GRIA4,LAMA2,SLC1A2,GABBR2,SMOC1,NTM,PTPRT,HS6ST3,NTRK2,ATP1A2,SPARCL1,CTNND2,AQP4,NPAS3,LIFR,NRG3,GRIK1,TNIK,GLIS3,CPE,GABRB1,SOX6,DTNA,DCLK1,PRKG1,DGKG,PCDH9,ZBTB20,DMD,LSAMP,CST3,MYO16,DPP6,CLU,GFAP,QKI,CTNNA3,PPP2R2B,GPM6A,GPM6B,SLC1A3,PHYHIPL,SASH1,PDZRN4
2.463e-03	-6.01	glial cell proliferation	biological process	GO:0014009	28	2	18204	48	CLU,GFAP
2.463e-03	-6.01	positive regulation of oligodendrocyte differentiation	biological process	GO:0048714	28	2	18204	48	PTPRZ1,QKI
2.463e-03	-6.01	startle response	biological process	GO:0001964	28	2	18204	48	CSMD1,GRID2
2.514e-03	-5.99	CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2)	protein interactions	10369	29	2	19454	50	GRIA4,GRIA1
2.529e-03	-5.98	cerebellum development	biological process	GO:0021549	103	3	18204	48	GRID2,MYO16,PRKG1
2.552e-03	-5.97	regulation of biological process	biological process	GO:0050789	12079	41	18204	48	QKI,CTNND2,SMOC1,MYO16,GPM6A,GRIA1,GRID2,PTPRZ1,CST3,CTNNA3,SPON1,GLIS3,CLU,GRIA4,SLC1A2,GABRB1,NRG3,DGKG,LIFR,LAMA2,ZBTB20,ATP1A2,DPP6,SOX6,CPE,TNIK,PRKG1,MAPK10,SASH1,DTNA,GFAP,SLC1A3,NPAS3,NTRK2,DCLK1,GRIK1,GABBR2,SPARCL1,PTPRT,DMD,GPM6B
2.563e-03	-5.97	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	8	16828	48	DCLK1,HS6ST3,GRID2,PCDH9,GLIS3,CTNNA3,PTPRT,PDZRN4
2.564e-03	-5.97	perinuclear endoplasmic reticulum lumen	cellular component	GO:0099020	1	1	19108	49	CLU
2.570e-03	-5.96	Ptk2 (protein tyrosine kinase 2)	protein interactions	25614	1	1	19454	50	DMD
2.570e-03	-5.96	Bdnf (brain derived neurotrophic factor)	protein interactions	12064	1	1	19454	50	NTRK2
2.570e-03	-5.96	Hipk3 (homeodomain interacting protein kinase 3)	protein interactions	15259	1	1	19454	50	GLIS3
2.570e-03	-5.96	DAG1 (dystroglycan 1)	protein interactions	281439	1	1	19454	50	LAMA2
2.570e-03	-5.96	IML3 (Iml3p)	protein interactions	852404	1	1	19454	50	GFAP
2.570e-03	-5.96	Dynlt1 (dynein light chain Tctex-type 1)	protein interactions	83462	1	1	19454	50	NTRK2
2.570e-03	-5.96	Isl1 (ISL1 transcription factor, LIM/homeodomain)	protein interactions	16392	1	1	19454	50	GLIS3
2.585e-03	-5.96	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma	1485	11	16828	48	LAMA2,PTPRT,PDZRN4,DPP6,PCDH9,DGKG,NRG3,PTPRZ1,GABRB1,DTNA,NPAS3
2.620e-03	-5.94	ovary-carcinoma-clear_cell_carcinoma	COSMIC cancer mutations	ovary-carcinoma-clear_cell_carcinoma	665	7	16828	48	SPARCL1,NTRK2,TNIK,DCLK1,MYO16,PRKG1,LIFR
2.620e-03	-5.94	regulation of synaptic plasticity	biological process	GO:0048167	219	4	18204	48	NTRK2,GRID2,GRIA1,GFAP
2.623e-03	-5.94	cell junction organization	biological process	GO:0034330	532	6	18204	48	GRID2,GRIA1,NRG3,SPARCL1,CTNND2,GPM6A
2.637e-03	-5.94	olfactory cortex development	biological process	GO:0021989	1	1	18204	48	ATP1A2
2.637e-03	-5.94	positive regulation of neurofibrillary tangle assembly	biological process	GO:1902998	1	1	18204	48	CLU
2.637e-03	-5.94	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological process	GO:0099551	1	1	18204	48	NTRK2
2.637e-03	-5.94	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological process	GO:0021840	1	1	18204	48	NRG3
2.637e-03	-5.94	regulation of neuronal signal transduction	biological process	GO:1902847	1	1	18204	48	CLU
2.637e-03	-5.94	negative regulation of collagen catabolic process	biological process	GO:0010711	1	1	18204	48	CST3
2.637e-03	-5.94	negative regulation of calcium:sodium antiporter activity	biological process	GO:1903280	1	1	18204	48	ATP1A2
2.637e-03	-5.94	negative regulation of elastin catabolic process	biological process	GO:0060311	1	1	18204	48	CST3
2.637e-03	-5.94	trans-synaptic signaling by neuropeptide	biological process	GO:0099540	1	1	18204	48	NTRK2
2.637e-03	-5.94	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological process	GO:0021842	1	1	18204	48	NRG3
2.641e-03	-5.94	gamma-aminobutyric acid signaling pathway	biological process	GO:0007214	29	2	18204	48	GABRB1,GABBR2
2.690e-03	-5.92	GRIA3 (glutamate ionotropic receptor AMPA type subunit 3)	protein interactions	2892	30	2	19454	50	GRIA1,GRIA4
2.697e-03	-5.92	STAR_dimer	pfam domains	PF16544	1	1	17795	48	QKI
2.697e-03	-5.92	Quaking_NLS	pfam domains	PF16551	1	1	17795	48	QKI
2.697e-03	-5.92	LIFR_N	pfam domains	PF18207	1	1	17795	48	LIFR
2.697e-03	-5.92	GBR2_CC	pfam domains	PF18455	1	1	17795	48	GABBR2
2.697e-03	-5.92	PKcGMP_CC	pfam domains	PF16808	1	1	17795	48	PRKG1
2.700e-03	-5.91	GBR2_CC	interpro domains	IPR041689	1	1	18521	50	GABBR2
2.700e-03	-5.91	SMOC1_EC	interpro domains	IPR037639	1	1	18521	50	SMOC1
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	SASH1_SAM_repeat2	interpro domains	IPR037630	1	1	18521	50	SASH1
2.700e-03	-5.91	M14_CPE_CPD	interpro domains	IPR034232	1	1	18521	50	CPE
2.700e-03	-5.91	PKcGMP_CC	interpro domains	IPR031831	1	1	18521	50	PRKG1
2.700e-03	-5.91	GPCR_3_GABA_rcpt_B2	interpro domains	IPR002457	1	1	18521	50	GABBR2
2.700e-03	-5.91	SASH1_SAM_repeat1	interpro domains	IPR037627	1	1	18521	50	SASH1
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	SASH1_SH3	interpro domains	IPR035720	1	1	18521	50	SASH1
2.700e-03	-5.91	LIFR_N	interpro domains	IPR040901	1	1	18521	50	LIFR
2.700e-03	-5.91	C1_DGKgamma_rpt2	interpro domains	IPR047475	1	1	18521	50	DGKG
2.700e-03	-5.91	Clusterin_CS	interpro domains	IPR033986	1	1	18521	50	CLU
2.700e-03	-5.91	MYSc_Myo16	interpro domains	IPR036042	1	1	18521	50	MYO16
2.700e-03	-5.91	NTRK2	interpro domains	IPR020455	1	1	18521	50	NTRK2
2.700e-03	-5.91	Clusterin	interpro domains	IPR016016	1	1	18521	50	CLU
2.700e-03	-5.91	SPARC-like_p1	interpro domains	IPR016359	1	1	18521	50	SPARCL1
2.709e-03	-5.91	clear_cell_carcinoma	COSMIC cancer mutations	clear_cell_carcinoma	669	7	16828	48	SPARCL1,NTRK2,TNIK,DCLK1,MYO16,PRKG1,LIFR
2.751e-03	-5.90	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	47	16828	48	SLC1A3,PHYHIPL,SASH1,PDZRN4,DMD,MYO16,LSAMP,CLU,DPP6,GPM6A,GPM6B,GFAP,QKI,CTNNA3,PPP2R2B,GABRB1,SOX6,DTNA,DCLK1,PRKG1,PCDH9,DGKG,ZBTB20,LIFR,NPAS3,GLIS3,CPE,NRG3,GRIK1,TNIK,HS6ST3,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,GABBR2,SMOC1,NTM,PTPRT,SLC1A2,SPON1,GRID2,PTPRZ1,GRIA1,LAMA2,GRIA4
2.763e-03	-5.89	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	50	QKI
2.763e-03	-5.89	brain-derived neurotrophic factor receptor activity	molecular function	GO:0060175	1	1	18094	50	NTRK2
2.825e-03	-5.87	L-glutamate import	biological process	GO:0051938	30	2	18204	48	SLC1A3,SLC1A2
2.870e-03	-5.85	SNTG1 (syntrophin gamma 1)	protein interactions	54212	31	2	19454	50	DTNA,DMD
2.884e-03	-5.85	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma	208	4	16828	48	GRID2,SMOC1,TNIK,PCDH9
2.897e-03	-5.84	amino acid:monoatomic cation symporter activity	molecular function	GO:0005416	29	2	18094	50	SLC1A3,SLC1A2
2.897e-03	-5.84	G-protein alpha-subunit binding	molecular function	GO:0001965	29	2	18094	50	GRIA1,SASH1
2.918e-03	-5.84	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	21	16828	48	LAMA2,CTNNA3,PPP2R2B,PTPRT,CLU,GRIA1,GLIS3,DPP6,PTPRZ1,GRID2,GABBR2,SPON1,NPAS3,AQP4,CTNND2,PDZRN4,SASH1,SPARCL1,DCLK1,SOX6,SLC1A3
2.934e-03	-5.83	extracellular matrix	cellular component	GO:0031012	559	6	19108	49	CLU,PTPRZ1,SMOC1,SPON1,SPARCL1,LAMA2
2.960e-03	-5.82	external encapsulating structure	cellular component	GO:0030312	560	6	19108	49	SPARCL1,LAMA2,PTPRZ1,CLU,SMOC1,SPON1
2.983e-03	-5.81	cell-cell adhesion	biological process	GO:0098609	546	6	18204	48	CTNND2,SPARCL1,PCDH9,PTPRT,GRID2,CTNNA3
3.015e-03	-5.80	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological process	GO:0010880	31	2	18204	48	DMD,ATP1A2
3.028e-03	-5.80	large_intestine-colon	COSMIC cancer mutations	large_intestine-colon	1291	10	16828	48	DMD,MYO16,PTPRZ1,SASH1,DPP6,GRIA1,GRIK1,LAMA2,ZBTB20,PTPRT
3.057e-03	-5.79	GRIA4 (glutamate ionotropic receptor AMPA type subunit 4)	protein interactions	2893	32	2	19454	50	GRIA1,GRIA4
3.060e-03	-5.79	Ig-like_fold	interpro domains	IPR013783	721	7	18521	50	LSAMP,NTRK2,PHYHIPL,PTPRZ1,LIFR,PTPRT,NTM
3.127e-03	-5.77	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	27	16828	48	GRIA1,GLIS3,NRG3,GRIA4,LAMA2,GRID2,PTPRZ1,PCDH9,DGKG,ZBTB20,SOX6,GABRB1,DTNA,PRKG1,CLU,GPM6A,PTPRT,CTNNA3,DMD,SMOC1,MYO16,SPARCL1,SASH1,NTRK2,ATP1A2,PDZRN4,SLC1A3
3.143e-03	-5.76	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	27	16828	48	NRG3,GRIA1,GLIS3,LAMA2,GRIA4,PTPRZ1,GRID2,DGKG,PCDH9,ZBTB20,DTNA,SOX6,GABRB1,PRKG1,CLU,CTNNA3,PTPRT,GPM6A,DMD,MYO16,SMOC1,ATP1A2,NTRK2,SASH1,SPARCL1,PDZRN4,SLC1A3
3.175e-03	-5.75	upper_leg	COSMIC cancer mutations	upper_leg	880	8	16828	48	DCLK1,GRID2,HS6ST3,PTPRT,PDZRN4,CTNNA3,GLIS3,PCDH9
3.206e-03	-5.74	regulation of gliogenesis	biological process	GO:0014013	112	3	18204	48	QKI,PTPRZ1,GFAP
3.211e-03	-5.74	transepithelial transport	biological process	GO:0070633	32	2	18204	48	SLC1A3,SLC1A2
3.211e-03	-5.74	peptidyl-tyrosine dephosphorylation	biological process	GO:0035335	32	2	18204	48	PTPRZ1,PTPRT
3.220e-03	-5.74	beta-catenin binding	molecular function	GO:0008013	107	3	18094	50	CTNND2,PTPRT,CTNNA3
3.248e-03	-5.73	-	gene3d domains	1.20.5.4010	1	1	14470	47	QKI
3.288e-03	-5.72	dendrite development	biological process	GO:0016358	113	3	18204	48	DCLK1,CTNND2,PRKG1
3.288e-03	-5.72	metencephalon development	biological process	GO:0022037	113	3	18204	48	PRKG1,MYO16,GRID2
3.330e-03	-5.70	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	3	16828	48	NRG3,PRKG1,QKI
3.356e-03	-5.70	Kazal_2	pfam domains	PF07648	32	2	17795	48	SMOC1,SPARCL1
3.357e-03	-5.70	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma	217	4	16828	48	DTNA,DMD,LAMA2,PTPRT
3.367e-03	-5.69	PRKCA (protein kinase C alpha)	protein interactions	5578	395	5	19454	50	GFAP,PRKG1,GRIA4,GPM6A,GRIA1
3.371e-03	-5.69	Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity	REACTOME pathways	R-HSA-399721	32	2	10285	28	GRIA4,GRIA1
3.371e-03	-5.69	Trafficking of AMPA receptors	REACTOME pathways	R-HSA-399719	32	2	10285	28	GRIA1,GRIA4
3.412e-03	-5.68	response to auditory stimulus	biological process	GO:0010996	33	2	18204	48	SLC1A3,ATP1A2
3.426e-03	-5.68	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-extraskeletal-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	891	8	16828	48	GABBR2,NPAS3,PTPRZ1,ATP1A2,DGKG,SPARCL1,PPP2R2B,CTNNA3
3.447e-03	-5.67	CLUSTERIN_1	prosite domains	PS00492	1	1	12186	42	CLU
3.447e-03	-5.67	CLUSTERIN_2	prosite domains	PS00493	1	1	12186	42	CLU
3.705e-03	-5.60	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	13	16828	48	GABRB1,PCDH9,AQP4,GABBR2,LSAMP,PTPRZ1,MYO16,NRG3,GFAP,PTPRT,CTNNA3,PPP2R2B,GPM6A
3.709e-03	-5.60	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	21	16828	48	CLU,GRIA1,GLIS3,DPP6,PTPRT,PPP2R2B,CTNNA3,LAMA2,NPAS3,GABBR2,SPON1,GRID2,PTPRZ1,SASH1,SPARCL1,PDZRN4,CTNND2,AQP4,SLC1A3,SOX6,DCLK1
3.714e-03	-5.60	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	9	16828	48	GRID2,PRKG1,MYO16,GABRB1,LIFR,CTNND2,PPP2R2B,CTNNA3,NTM
3.717e-03	-5.59	extraskeletal	COSMIC cancer mutations	extraskeletal	903	8	16828	48	SPARCL1,DGKG,ATP1A2,PPP2R2B,CTNNA3,NPAS3,GABBR2,PTPRZ1
3.821e-03	-5.57	NK-T_cell_lymphoma	COSMIC cancer mutations	NK-T_cell_lymphoma	225	4	16828	48	DMD,DTNA,LAMA2,PTPRT
3.823e-03	-5.57	human chr8p23.2	chromosome location	human chr8p23.2	2	1	26134	50	CSMD1
3.832e-03	-5.56	regulation of cardiac muscle cell contraction	biological process	GO:0086004	35	2	18204	48	CTNNA3,ATP1A2
3.857e-03	-5.56	OSBPL1A (oxysterol binding protein like 1A)	protein interactions	114876	36	2	19454	50	DMD,CTNNA3
3.858e-03	-5.56	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	11	18204	48	CLU,NTRK2,GPM6B,ZBTB20,QKI,ATP1A2,SOX6,PTPRZ1,GRID2,GFAP,SASH1
3.860e-03	-5.56	regulation of neuron apoptotic process	biological process	GO:0043523	244	4	18204	48	GRID2,PTPRZ1,NTRK2,CLU
3.893e-03	-5.55	striated muscle contraction	biological process	GO:0006941	120	3	18204	48	DTNA,DMD,ATP1A2
3.898e-03	-5.55	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-polycythaemia_vera	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-polycythaemia_vera	369	5	16828	48	NTRK2,CTNND2,CTNNA3,DCLK1,LAMA2
3.898e-03	-5.55	polycythaemia_vera	COSMIC cancer mutations	polycythaemia_vera	369	5	16828	48	NTRK2,DCLK1,LAMA2,CTNND2,CTNNA3
3.904e-03	-5.55	functioning	COSMIC cancer mutations	functioning	1803	12	16828	48	SLC1A2,DMD,PTPRZ1,MYO16,GRIK1,DGKG,NRG3,NTRK2,PCDH9,GRIA1,CTNNA3,ZBTB20
3.904e-03	-5.55	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning	1803	12	16828	48	GRIK1,NTRK2,DGKG,NRG3,PCDH9,GRIA1,CTNNA3,ZBTB20,SLC1A2,DMD,PTPRZ1,MYO16
3.973e-03	-5.53	positive regulation of neurogenesis	biological process	GO:0050769	246	4	18204	48	PTPRZ1,GFAP,QKI,NTRK2
3.973e-03	-5.53	regulation of synapse organization	biological process	GO:0050807	246	4	18204	48	PTPRT,GRID2,NTRK2,GPM6A
4.049e-03	-5.51	Salivary secretion	KEGG pathways	ko04970	90	3	7161	26	ATP1A2,CST3,PRKG1
4.049e-03	-5.51	Salivary secretion	KEGG pathways	hsa04970	90	3	7161	26	PRKG1,ATP1A2,CST3
4.071e-03	-5.50	SERTAD2 (SERTA domain containing 2)	protein interactions	9792	37	2	19454	50	CTNNA3,PPP2R2B
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	QKI,ZBTB20
4.071e-03	-5.50	MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)	protein interactions	9863	37	2	19454	50	CTNND2,GRID2
4.071e-03	-5.50	HPCA (hippocalcin)	protein interactions	3208	37	2	19454	50	GPM6A,CST3
4.079e-03	-5.50	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	44	16828	48	PDZRN4,SASH1,PHYHIPL,SLC1A3,GPM6B,GPM6A,QKI,CTNNA3,PPP2R2B,GFAP,CLU,DPP6,MYO16,LSAMP,DMD,ZBTB20,PCDH9,DGKG,PRKG1,DCLK1,GABRB1,SOX6,CPE,GLIS3,TNIK,GRIK1,NRG3,LIFR,AQP4,CTNND2,SPARCL1,ATP1A2,NTRK2,HS6ST3,PTPRT,NTM,SMOC1,GABBR2,SLC1A2,LAMA2,GRIA4,GRIA1,GRID2,SPON1
4.148e-03	-5.49	regulation of muscle system process	biological process	GO:0090257	249	4	18204	48	DMD,CTNNA3,PRKG1,ATP1A2
4.150e-03	-5.48	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	20	16828	48	PTPRT,CTNNA3,GPM6A,GPM6B,TNIK,GLIS3,GRID2,PTPRZ1,NPAS3,PDZRN4,CTNND2,AQP4,DGKG,NTRK2,ATP1A2,SASH1,PCDH9,PRKG1,SLC1A2,SOX6
4.163e-03	-5.48	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	20	16828	48	PDZRN4,CTNND2,AQP4,DGKG,NTRK2,ATP1A2,PCDH9,SASH1,PRKG1,SLC1A2,SOX6,PTPRT,CTNNA3,GPM6A,GPM6B,TNIK,GLIS3,GRID2,PTPRZ1,NPAS3
4.188e-03	-5.48	FN3	prosite domains	PS50853	192	4	12186	42	PTPRZ1,PHYHIPL,LIFR,PTPRT
4.201e-03	-5.47	organic acid:sodium symporter activity	molecular function	GO:0005343	35	2	18094	50	SLC1A3,SLC1A2
4.275e-03	-5.45	response to antibiotic	biological process	GO:0046677	37	2	18204	48	SLC1A3,GRIA1
4.281e-03	-5.45	cell adhesion molecule binding	molecular function	GO:0050839	560	6	18094	50	PTPRZ1,CTNND2,CTNNA3,CPE,GFAP,PTPRT
4.321e-03	-5.44	neuron projection terminus	cellular component	GO:0044306	128	3	19108	49	SLC1A2,DMD,NTRK2
4.328e-03	-5.44	regulation of synapse structure or activity	biological process	GO:0050803	252	4	18204	48	GPM6A,NTRK2,PTPRT,GRID2
4.352e-03	-5.44	CDCA8 (cell division cycle associated 8)	protein interactions	55143	128	3	19454	50	PPP2R2B,GPM6B,DCLK1
4.400e-03	-5.43	NTKRECEPTOR2	prints domains	PR01941	1	1	5227	23	NTRK2
4.400e-03	-5.43	GABAB2RECPTR	prints domains	PR01178	1	1	5227	23	GABBR2
4.400e-03	-5.43	AQUAPORIN4	prints domains	PR02016	1	1	5227	23	AQP4
4.481e-03	-5.41	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	2081	13	16828	48	PTPRZ1,DCLK1,PRKG1,GABBR2,DMD,SOX6,DTNA,PDZRN4,GFAP,LAMA2,NTRK2,TNIK,ATP1A2
4.562e-03	-5.39	response to amino acid	biological process	GO:0043200	127	3	18204	48	NTRK2,SLC1A2,GRIA1
4.590e-03	-5.38	lung-middle_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-middle_lobe-carcinoma-adenocarcinoma	1368	10	16828	48	ATP1A2,GRIK1,PCDH9,SASH1,CPE,CTNND2,PDZRN4,PHYHIPL,SMOC1,DCLK1
4.594e-03	-5.38	Arrhythmogenic Right Ventricular Cardiomyopathy	WikiPathways	WP2118	76	3	5310	24	DMD,CTNNA3,LAMA2
4.617e-03	-5.38	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	20	16828	48	AQP4,PDZRN4,CTNND2,PCDH9,SASH1,NTRK2,DGKG,ATP1A2,PRKG1,SOX6,SLC1A2,GPM6A,GPM6B,PTPRT,CTNNA3,GLIS3,TNIK,GRID2,PTPRZ1,NPAS3
4.642e-03	-5.37	cell surface receptor signaling pathway	biological process	GO:0007166	1992	12	18204	48	NRG3,CPE,GRIK1,GRIA4,NTRK2,CTNND2,LIFR,GRIA1,GRID2,PTPRT,MAPK10,TNIK
4.684e-03	-5.36	DISC1 (DISC1 scaffold protein)	protein interactions	27185	427	5	19454	50	TNIK,DMD,CTNNA3,CLU,SPARCL1
4.692e-03	-5.36	regulation of multicellular organismal process	biological process	GO:0051239	3113	16	18204	48	PTPRZ1,GRID2,CST3,SASH1,CTNNA3,GFAP,PRKG1,SOX6,QKI,ZBTB20,ATP1A2,DMD,GPM6B,LAMA2,CLU,NTRK2
4.741e-03	-5.35	sodium ion homeostasis	biological process	GO:0055078	39	2	18204	48	SLC1A3,ATP1A2
4.741e-03	-5.35	maintenance of blood-brain barrier	biological process	GO:0035633	39	2	18204	48	DMD,LAMA2
4.741e-03	-5.35	cellular response to alkaloid	biological process	GO:0071312	39	2	18204	48	SLC1A2,SLC1A3
4.744e-03	-5.35	CTNNBIP1 (catenin beta interacting protein 1)	protein interactions	56998	40	2	19454	50	PPP2R2B,CTNNA3
4.838e-03	-5.33	axon development	biological process	GO:0061564	420	5	18204	48	LAMA2,GPM6B,PTPRZ1,DCLK1,PRKG1
4.855e-03	-5.33	Circadian entrainment	KEGG pathways	hsa04713	96	3	7161	26	GRIA4,GRIA1,PRKG1
4.855e-03	-5.33	Circadian entrainment	KEGG pathways	ko04713	96	3	7161	26	PRKG1,GRIA4,GRIA1
4.899e-03	-5.32	cell-cell adhesion via plasma-membrane adhesion molecules	biological process	GO:0098742	261	4	18204	48	GRID2,PTPRT,PCDH9,SPARCL1
4.934e-03	-5.31	middle_lobe	COSMIC cancer mutations	middle_lobe	1382	10	16828	48	PDZRN4,CTNND2,CPE,PCDH9,SASH1,ATP1A2,GRIK1,SMOC1,DCLK1,PHYHIPL
4.974e-03	-5.30	carboxylic acid transmembrane transport	biological process	GO:1905039	131	3	18204	48	SLC1A2,GFAP,SLC1A3
4.980e-03	-5.30	TAFA2 (TAFA chemokine like family member 2)	protein interactions	338811	41	2	19454	50	LIFR,CPE
5.085e-03	-5.28	essential_thrombocythaemia	COSMIC cancer mutations	essential_thrombocythaemia	393	5	16828	48	GRIA4,PDZRN4,SASH1,DTNA,DMD
5.085e-03	-5.28	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-essential_thrombocythaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-essential_thrombocythaemia	393	5	16828	48	PDZRN4,GRIA4,DTNA,SASH1,DMD
5.094e-03	-5.28	system process	biological process	GO:0003008	2015	12	18204	48	CSMD1,ATP1A2,GRIA1,GRID2,PTPRZ1,DTNA,PRKG1,SLC1A2,SLC1A3,AQP4,NTRK2,DMD
5.122e-03	-5.27	axonal spine	cellular component	GO:0044308	2	1	19108	49	GRIA1
5.122e-03	-5.27	perisynaptic space	cellular component	GO:0099544	2	1	19108	49	GRIA1
5.122e-03	-5.27	G protein-coupled GABA receptor complex	cellular component	GO:1902712	2	1	19108	49	GABBR2
5.134e-03	-5.27	Frrs1l (ferric-chelate reductase 1 like)	protein interactions	230235	2	1	19454	50	GRIA1
5.134e-03	-5.27	TRIM39-RPP21 (TRIM39-RPP21 readthrough)	protein interactions	202658	2	1	19454	50	PRKG1
5.134e-03	-5.27	Kdm4c (lysine (K)-specific demethylase 4C)	protein interactions	76804	2	1	19454	50	GLIS3
5.134e-03	-5.27	URA1 (dihydroorotate dehydrogenase)	protein interactions	853664	2	1	19454	50	GFAP
5.134e-03	-5.27	Zmym2 (zinc finger, MYM-type 2)	protein interactions	76007	2	1	19454	50	GLIS3
5.134e-03	-5.27	Snta1 (syntrophin, alpha 1)	protein interactions	362242	2	1	19454	50	DMD
5.134e-03	-5.27	TARP (TCR gamma alternate reading frame protein)	protein interactions	445347	2	1	19454	50	GRIA1
5.220e-03	-5.26	E7 (early protein)	protein interactions	1489425	42	2	19454	50	SASH1,CLU
5.228e-03	-5.25	regulation of actin filament-based movement	biological process	GO:1903115	41	2	18204	48	ATP1A2,CTNNA3
5.265e-03	-5.25	amide binding	molecular function	GO:0033218	254	4	18094	50	CST3,GRIA1,CLU,GRIA4
5.267e-03	-5.25	negative regulation of blood vessel remodeling	biological process	GO:0060313	2	1	18204	48	CST3
5.267e-03	-5.25	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	48	CLU
5.267e-03	-5.25	negative regulation of inositol phosphate biosynthetic process	biological process	GO:0010920	2	1	18204	48	PRKG1
5.267e-03	-5.25	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	48	QKI
5.267e-03	-5.25	myofibroblast contraction	biological process	GO:1990764	2	1	18204	48	QKI
5.267e-03	-5.25	regulation of elastin catabolic process	biological process	GO:0060310	2	1	18204	48	CST3
5.388e-03	-5.22	Thyroglob_assoc	pfam domains	PF16597	2	1	17795	48	SMOC1
5.388e-03	-5.22	Spond_N	pfam domains	PF06468	2	1	17795	48	SPON1
5.388e-03	-5.22	Reeler	pfam domains	PF02014	2	1	17795	48	SPON1
5.388e-03	-5.22	LIFR_D2	pfam domains	PF17971	2	1	17795	48	LIFR
5.388e-03	-5.22	Clusterin	pfam domains	PF01093	2	1	17795	48	CLU
5.388e-03	-5.22	PHYHIP_C	pfam domains	PF19281	2	1	17795	48	PHYHIPL
5.388e-03	-5.22	LIF-R_Ig-like	pfam domains	PF21177	2	1	17795	48	LIFR
5.392e-03	-5.22	Clusterin_C	interpro domains	IPR016015	2	1	18521	50	CLU
5.392e-03	-5.22	Clusterin-like	interpro domains	IPR000753	2	1	18521	50	CLU
5.392e-03	-5.22	Spondin_N	interpro domains	IPR009465	2	1	18521	50	SPON1
5.392e-03	-5.22	LIFR_D2	interpro domains	IPR040817	2	1	18521	50	LIFR
5.392e-03	-5.22	PHYHIP/PHYHIPL	interpro domains	IPR042868	2	1	18521	50	PHYHIPL
5.392e-03	-5.22	STKc_cGK	interpro domains	IPR035014	2	1	18521	50	PRKG1
5.392e-03	-5.22	Dystrophin/utrophin	interpro domains	IPR035436	2	1	18521	50	DMD
5.392e-03	-5.22	Alpha_CARP_receptor-type	interpro domains	IPR041887	2	1	18521	50	PTPRZ1
5.392e-03	-5.22	Distrobrevin	interpro domains	IPR017432	2	1	18521	50	DTNA
5.392e-03	-5.22	Spondin_N_sf	interpro domains	IPR038678	2	1	18521	50	SPON1
5.392e-03	-5.22	cGMP_dep_kinase	interpro domains	IPR002374	2	1	18521	50	PRKG1
5.392e-03	-5.22	Osteonectin_CS	interpro domains	IPR001999	2	1	18521	50	SPARCL1
5.392e-03	-5.22	PHYIP/PHIPL_C	interpro domains	IPR045545	2	1	18521	50	PHYHIPL
5.392e-03	-5.22	LIF-R-like_Ig-like	interpro domains	IPR048497	2	1	18521	50	LIFR
5.392e-03	-5.22	Clusterin_N	interpro domains	IPR016014	2	1	18521	50	CLU
5.392e-03	-5.22	DCX_chordates	interpro domains	IPR017302	2	1	18521	50	DCLK1
5.407e-03	-5.22	organic acid transmembrane transport	biological process	GO:1903825	135	3	18204	48	SLC1A2,GFAP,SLC1A3
5.409e-03	-5.22	I-set	pfam domains	PF07679	132	3	17795	48	LSAMP,NTM,NTRK2
5.432e-03	-5.22	Ig_I-set	interpro domains	IPR013098	132	3	18521	50	NTM,LSAMP,NTRK2
5.438e-03	-5.21	Activation of Na-permeable Kainate Receptors	REACTOME pathways	R-HSA-451307	2	1	10285	28	GRIK1
5.481e-03	-5.21	regulation of amino acid transport	biological process	GO:0051955	42	2	18204	48	ATP1A2,PRKG1
5.489e-03	-5.21	Activation of NMDA receptor upon glutamate binding and postsynaptic events	REACTOME pathways	R-HSA-442755	41	2	10285	28	GRIA1,GRIA4
5.519e-03	-5.20	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	molecular function	GO:0150047	2	1	18094	50	GABRB1
5.519e-03	-5.20	cGMP-dependent protein kinase activity	molecular function	GO:0004692	2	1	18094	50	PRKG1
5.519e-03	-5.20	leukemia inhibitory factor receptor activity	molecular function	GO:0004923	2	1	18094	50	LIFR
5.562e-03	-5.19	peptide binding	molecular function	GO:0042277	258	4	18094	50	CLU,GRIA4,GRIA1,CST3
5.579e-03	-5.19	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	9	16828	48	LAMA2,DPP6,CPE,LSAMP,GRID2,DCLK1,MYO16,SPON1,DMD
5.672e-03	-5.17	face	COSMIC cancer mutations	face	2139	13	16828	48	PPP2R2B,CTNNA3,GFAP,PTPRT,AQP4,GPM6A,NRG3,PCDH9,PTPRZ1,LSAMP,MYO16,GABBR2,GABRB1
5.727e-03	-5.16	Y_phosphatase	pfam domains	PF00102	42	2	17795	48	PTPRZ1,PTPRT
5.737e-03	-5.16	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	48	ATP1A2,PRKG1,SLC1A3,SLC1A2
5.740e-03	-5.16	PTP_cat	interpro domains	IPR000242	42	2	18521	50	PTPRZ1,PTPRT
5.934e-03	-5.13	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	18	16828	48	DGKG,ATP1A2,SASH1,PCDH9,PDZRN4,CTNND2,ZBTB20,PRKG1,GRIA1,PTPRT,CTNNA3,LAMA2,NPAS3,SPON1,LIFR,GRID2,PTPRZ1,MYO16
5.946e-03	-5.12	spleen	COSMIC cancer mutations	spleen	408	5	16828	48	MYO16,GRID2,PTPRZ1,NTM,TNIK
5.980e-03	-5.12	neurotransmitter transport	biological process	GO:0006836	140	3	18204	48	ATP1A2,SLC1A3,SLC1A2
6.002e-03	-5.12	mammary gland morphogenesis	biological process	GO:0060443	44	2	18204	48	NRG3,CSMD1
6.005e-03	-5.12	neutral L-amino acid transmembrane transporter activity	molecular function	GO:0015175	42	2	18094	50	SLC1A2,SLC1A3
6.024e-03	-5.11	Signaling by ERBB4	REACTOME pathways	R-HSA-1236394	43	2	10285	28	GFAP,NRG3
6.045e-03	-5.11	regulation of neuron projection development	biological process	GO:0010975	443	5	18204	48	GRID2,GFAP,TNIK,DGKG,NTRK2
6.107e-03	-5.10	axon	cellular component	GO:0030424	650	6	19108	49	NTRK2,GRIA1,GPM6A,DTNA,PCDH9,SLC1A2
6.117e-03	-5.10	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma	1425	10	16828	48	SLC1A2,MYO16,ATP1A2,NTRK2,GRIA1,CLU,QKI,CTNND2,PTPRT,PDZRN4
6.117e-03	-5.10	nasopharyngeal_carcinoma	COSMIC cancer mutations	nasopharyngeal_carcinoma	1425	10	16828	48	SLC1A2,MYO16,ATP1A2,NTRK2,GRIA1,CLU,QKI,CTNND2,PTPRT,PDZRN4
6.145e-03	-5.09	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	27	16828	48	DPP6,GPM6B,CTNNA3,QKI,PTPRT,DMD,GABBR2,MYO16,NTRK2,AQP4,CTNND2,PDZRN4,PHYHIPL,CPE,GRIA1,NRG3,GRIA4,LAMA2,SPON1,NPAS3,PTPRZ1,GRID2,PCDH9,DGKG,ZBTB20,SOX6,DCLK1
6.219e-03	-5.08	monoatomic anion transmembrane transport	biological process	GO:0098656	142	3	18204	48	SLC1A3,GABRB1,SLC1A2
6.219e-03	-5.08	response to acid chemical	biological process	GO:0001101	142	3	18204	48	GRIA1,SLC1A2,NTRK2
6.234e-03	-5.08	RADX (RPA1 related single stranded DNA binding protein, X-linked)	protein interactions	55086	46	2	19454	50	SOX6,GABBR2
6.270e-03	-5.07	cell communication involved in cardiac conduction	biological process	GO:0086065	45	2	18204	48	ATP1A2,CTNNA3
6.316e-03	-5.06	signaling receptor activity	molecular function	GO:0038023	1474	10	18094	50	NTRK2,GABRB1,GABBR2,GRIK1,LIFR,PTPRZ1,GRIA1,GRID2,GRIA4,PTPRT
6.316e-03	-5.06	molecular transducer activity	molecular function	GO:0060089	1474	10	18094	50	GRIK1,LIFR,GABBR2,NTRK2,GABRB1,PTPRT,GRID2,GRIA4,GRIA1,PTPRZ1
6.412e-03	-5.05	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	48	16828	48	GLIS3,CPE,NRG3,GRIK1,TNIK,LIFR,NPAS3,ZBTB20,PCDH9,DGKG,DCLK1,PRKG1,SOX6,GABRB1,DTNA,GPM6A,GPM6B,GFAP,QKI,CTNNA3,PPP2R2B,CLU,DPP6,MYO16,LSAMP,CST3,DMD,PDZRN4,SASH1,SLC1A3,PHYHIPL,LAMA2,GRIA4,GRIA1,GRID2,PTPRZ1,SPON1,SLC1A2,PTPRT,NTM,SMOC1,GABBR2,AQP4,CTNND2,SPARCL1,NTRK2,ATP1A2,HS6ST3
6.441e-03	-5.05	membrane raft	cellular component	GO:0045121	290	4	19108	49	DMD,SLC1A2,ATP1A2,GPM6B
6.486e-03	-5.04	F-spondin domain	gene3d domains	2.60.40.2130	2	1	14470	47	SPON1
6.500e-03	-5.04	CNTN1 (contactin 1)	protein interactions	1272	47	2	19454	50	GPM6A,PTPRZ1
6.500e-03	-5.04	BDNF (brain derived neurotrophic factor)	protein interactions	627	47	2	19454	50	NTRK2,CPE
6.544e-03	-5.03	positive regulation of glial cell differentiation	biological process	GO:0045687	46	2	18204	48	PTPRZ1,QKI
6.544e-03	-5.03	regulation of oligodendrocyte differentiation	biological process	GO:0048713	46	2	18204	48	QKI,PTPRZ1
6.582e-03	-5.02	Non-integrin membrane-ECM interactions	REACTOME pathways	R-HSA-3000171	45	2	10285	28	DMD,LAMA2
6.597e-03	-5.02	membrane microdomain	cellular component	GO:0098857	292	4	19108	49	DMD,SLC1A2,ATP1A2,GPM6B
6.665e-03	-5.01	cell junction assembly	biological process	GO:0034329	285	4	18204	48	GPM6A,NRG3,GRIA1,GRID2
6.702e-03	-5.01	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	46	16828	48	SPON1,PTPRZ1,GRID2,GRIA1,LAMA2,GRIA4,SLC1A2,GABBR2,SMOC1,PTPRT,HS6ST3,ATP1A2,NTRK2,SPARCL1,CTNND2,AQP4,NPAS3,LIFR,GRIK1,TNIK,NRG3,CPE,GLIS3,DTNA,GABRB1,SOX6,PRKG1,DCLK1,DGKG,PCDH9,ZBTB20,DMD,LSAMP,MYO16,CLU,DPP6,QKI,CTNNA3,PPP2R2B,GFAP,GPM6B,GPM6A,PHYHIPL,SLC1A3,SASH1,PDZRN4
6.702e-03	-5.01	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	46	16828	48	SLC1A2,SPON1,PTPRZ1,GRID2,GRIA1,LAMA2,GRIA4,HS6ST3,SPARCL1,ATP1A2,NTRK2,AQP4,CTNND2,GABBR2,SMOC1,PTPRT,DTNA,SOX6,GABRB1,PRKG1,DCLK1,PCDH9,DGKG,ZBTB20,LIFR,NPAS3,CPE,GLIS3,TNIK,GRIK1,NRG3,PHYHIPL,SLC1A3,SASH1,PDZRN4,DMD,MYO16,LSAMP,DPP6,CLU,GPM6B,GPM6A,CTNNA3,QKI,PPP2R2B,GFAP
6.772e-03	-4.99	PATE1 (prostate and testis expressed 1)	protein interactions	160065	48	2	19454	50	SMOC1,CPE
6.782e-03	-4.99	localization	biological process	GO:0051179	4474	20	18204	48	GFAP,GRIA1,GRID2,GPM6A,TNIK,DPP6,CPE,ATP1A2,QKI,DMD,GPM6B,SLC1A2,GABRB1,GRIK1,GRIA4,DCLK1,NTRK2,CLU,SLC1A3,AQP4
6.815e-03	-4.99	regulation of nervous system development	biological process	GO:0051960	456	5	18204	48	PTPRZ1,GRID2,GFAP,QKI,NTRK2
6.824e-03	-4.99	Schwann cell differentiation	biological process	GO:0014037	47	2	18204	48	LAMA2,NTRK2
6.881e-03	-4.98	TNIK (TRAF2 and NCK interacting kinase)	protein interactions	23043	151	3	19454	50	PRKG1,TNIK,CLU
6.882e-03	-4.98	OSTEONECTIN_2	prosite domains	PS00613	2	1	12186	42	SPARCL1
6.882e-03	-4.98	SPONDIN	prosite domains	PS51020	2	1	12186	42	SPON1
6.882e-03	-4.98	OSTEONECTIN_1	prosite domains	PS00612	2	1	12186	42	SPARCL1
6.884e-03	-4.98	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	4	16828	48	SASH1,LIFR,GRIA4,CTNNA3
6.960e-03	-4.97	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	26	16828	48	SOX6,DTNA,DGKG,ZBTB20,NPAS3,LIFR,GRID2,PTPRZ1,NRG3,GLIS3,GRIA1,GRIA4,LAMA2,SLC1A3,NTRK2,ATP1A2,SASH1,SPARCL1,PDZRN4,CTNND2,DMD,CST3,SMOC1,MYO16,PTPRT,GPM6B
6.987e-03	-4.96	skin-neck-malignant_melanoma	COSMIC cancer mutations	skin-neck-malignant_melanoma	1223	9	16828	48	CTNND2,CTNNA3,PTPRT,LAMA2,ATP1A2,SASH1,GRID2,DCLK1,PHYHIPL
7.101e-03	-4.95	neuromuscular process	biological process	GO:0050905	149	3	18204	48	CSMD1,SLC1A3,GRID2
7.109e-03	-4.95	regulation of sodium ion transmembrane transporter activity	biological process	GO:2000649	48	2	18204	48	ATP1A2,DMD
7.110e-03	-4.95	acute_lymphoblastic_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_leukaemia	2197	13	16828	48	GFAP,LAMA2,TNIK,PTPRZ1,GABBR2,DMD,PDZRN4,NTRK2,ATP1A2,DCLK1,PRKG1,SOX6,DTNA
7.145e-03	-4.94	Kazal_dom_sf	interpro domains	IPR036058	47	2	18521	50	SPARCL1,SMOC1
7.155e-03	-4.94	TYR_PHOSPHATASE_PTP	prosite domains	PS50055	37	2	12186	42	PTPRT,PTPRZ1
7.272e-03	-4.92	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	3	16828	48	NRG3,PRKG1,QKI
7.284e-03	-4.92	neck	COSMIC cancer mutations	neck	1231	9	16828	48	ATP1A2,SASH1,PTPRT,CTNNA3,CTNND2,LAMA2,PHYHIPL,GRID2,DCLK1
7.322e-03	-4.92	cellular response to organic cyclic compound	biological process	GO:0071407	464	5	18204	48	GRIA1,GABRB1,SLC1A2,SLC1A3,ATP1A2
7.399e-03	-4.91	oligodendrocyte development	biological process	GO:0014003	49	2	18204	48	GPM6B,CLU
7.399e-03	-4.91	ARRB1 (arrestin beta 1)	protein interactions	408	301	4	19454	50	DGKG,SASH1,MAPK10,DMD
7.443e-03	-4.90	Kazal_dom	interpro domains	IPR002350	48	2	18521	50	SPARCL1,SMOC1
7.524e-03	-4.89	monoatomic cation transmembrane transporter activity	molecular function	GO:0008324	630	6	18094	50	GPM6A,GRIA1,ATP1A2,GRIK1,SLC1A2,SLC1A3
7.581e-03	-4.88	intercalated disc	cellular component	GO:0014704	51	2	19108	49	CTNNA3,ATP1A2
7.674e-03	-4.87	G protein-coupled receptor heterodimeric complex	cellular component	GO:0038039	3	1	19108	49	GABBR2
7.689e-03	-4.87	carboxylic acid transport	biological process	GO:0046942	297	4	18204	48	NTRK2,SLC1A3,SLC1A2,GFAP
7.689e-03	-4.87	muscle system process	biological process	GO:0003012	297	4	18204	48	PRKG1,ATP1A2,DMD,DTNA
7.691e-03	-4.87	Spop (speckle-type BTB/POZ protein)	protein interactions	20747	3	1	19454	50	GLIS3
7.691e-03	-4.87	Lep (leptin)	protein interactions	16846	3	1	19454	50	CLU
7.691e-03	-4.87	Slc8a1 (solute carrier family 8 (sodium/calcium exchanger), member 1)	protein interactions	20541	3	1	19454	50	DMD
7.691e-03	-4.87	QRFPR (pyroglutamylated RFamide peptide receptor)	protein interactions	84109	3	1	19454	50	NTM
7.691e-03	-4.87	Itgb1 (integrin subunit beta 1)	protein interactions	24511	3	1	19454	50	DMD
7.691e-03	-4.87	IL34 (interleukin 34)	protein interactions	146433	3	1	19454	50	PTPRZ1
7.694e-03	-4.87	cellular response to nerve growth factor stimulus	biological process	GO:1990090	50	2	18204	48	NTRK2,GRIA1
7.774e-03	-4.86	hindbrain development	biological process	GO:0030902	154	3	18204	48	GRID2,MYO16,PRKG1
7.774e-03	-4.86	learning	biological process	GO:0007612	154	3	18204	48	ATP1A2,NTRK2,CSMD1
7.779e-03	-4.86	organic acid transport	biological process	GO:0015849	298	4	18204	48	NTRK2,SLC1A3,SLC1A2,GFAP
7.788e-03	-4.86	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	6	18204	48	GFAP,GRID2,GPM6A,NTRK2,TNIK,DGKG
7.890e-03	-4.84	positive regulation of Schwann cell proliferation	biological process	GO:0010625	3	1	18204	48	GFAP
7.890e-03	-4.84	cellular response to amine stimulus	biological process	GO:0071418	3	1	18204	48	GRIA1
7.890e-03	-4.84	mammary placode formation	biological process	GO:0060596	3	1	18204	48	NRG3
7.890e-03	-4.84	cysteine transport	biological process	GO:0042883	3	1	18204	48	SLC1A2
7.890e-03	-4.84	Schwann cell proliferation	biological process	GO:0014010	3	1	18204	48	GFAP
7.890e-03	-4.84	negative regulation of serotonin uptake	biological process	GO:0051612	3	1	18204	48	GPM6B
7.890e-03	-4.84	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological process	GO:0099183	3	1	18204	48	NTRK2
7.890e-03	-4.84	immune complex clearance	biological process	GO:0002434	3	1	18204	48	CLU
7.890e-03	-4.84	negative regulation of neurotransmitter uptake	biological process	GO:0051581	3	1	18204	48	GPM6B
7.890e-03	-4.84	cysteine transmembrane transport	biological process	GO:1903712	3	1	18204	48	SLC1A2
7.890e-03	-4.84	protein targeting to lysosome involved in chaperone-mediated autophagy	biological process	GO:0061740	3	1	18204	48	CLU
7.890e-03	-4.84	regulation of calcium:sodium antiporter activity	biological process	GO:1903279	3	1	18204	48	ATP1A2
7.928e-03	-4.84	EPB41L1 (erythrocyte membrane protein band 4.1 like 1)	protein interactions	2036	159	3	19454	50	GRIA4,GPM6A,GRIA1
8.049e-03	-4.82	KAZAL	smart domains	SM00280	33	2	9717	40	SMOC1,SPARCL1
8.071e-03	-4.82	SLY	pfam domains	PF12485	3	1	17795	48	SASH1
8.071e-03	-4.82	NYAP_C	pfam domains	PF15452	3	1	17795	48	MYO16
8.071e-03	-4.82	LRRCT_2	pfam domains	PF16920	3	1	17795	48	NTRK2
8.071e-03	-4.82	NYAP_N	pfam domains	PF15439	3	1	17795	48	MYO16
8.071e-03	-4.82	DAG_kinase_N	pfam domains	PF14513	3	1	17795	48	DGKG
8.078e-03	-4.82	NYAP_N	interpro domains	IPR039482	3	1	18521	50	MYO16
8.078e-03	-4.82	Heparan_SO4-6-sulfoTrfase	interpro domains	IPR010635	3	1	18521	50	HS6ST3
8.078e-03	-4.82	SPIDER	interpro domains	IPR021090	3	1	18521	50	SASH1
8.078e-03	-4.82	DAG_kinase_typeI_N	interpro domains	IPR029477	3	1	18521	50	DGKG
8.078e-03	-4.82	Reeler_sf	interpro domains	IPR042307	3	1	18521	50	SPON1
8.078e-03	-4.82	Neuregulin	interpro domains	IPR040180	3	1	18521	50	NRG3
8.078e-03	-4.82	NTRK	interpro domains	IPR020777	3	1	18521	50	NTRK2
8.078e-03	-4.82	GABAAb_rcpt	interpro domains	IPR002289	3	1	18521	50	GABRB1
8.078e-03	-4.82	GPCR3_GABA-B	interpro domains	IPR002455	3	1	18521	50	GABBR2
8.078e-03	-4.82	DGK_typeI_N_sf	interpro domains	IPR038199	3	1	18521	50	DGKG
8.078e-03	-4.82	MAPK_JNK	interpro domains	IPR008351	3	1	18521	50	MAPK10
8.078e-03	-4.82	NYAP_C	interpro domains	IPR029353	3	1	18521	50	MYO16
8.078e-03	-4.82	Reeler_dom	interpro domains	IPR002861	3	1	18521	50	SPON1
8.078e-03	-4.82	NTRK_LRRCT	interpro domains	IPR031635	3	1	18521	50	NTRK2
8.183e-03	-4.81	Immunoglobulins	gene3d domains	2.60.40.10	721	7	14470	47	PTPRT,LIFR,PHYHIPL,PTPRZ1,LSAMP,NTRK2,NTM
8.200e-03	-4.80	pancreas-carcinoma-acinar_carcinoma	COSMIC cancer mutations	pancreas-carcinoma-acinar_carcinoma	1978	12	16828	48	PTPRZ1,DMD,LIFR,SPON1,LAMA2,QKI,GRIA1,PHYHIPL,ZBTB20,CTNND2,SASH1,ATP1A2
8.200e-03	-4.80	acinar_carcinoma	COSMIC cancer mutations	acinar_carcinoma	1978	12	16828	48	PHYHIPL,SASH1,ATP1A2,ZBTB20,CTNND2,LIFR,DMD,SPON1,PTPRZ1,GRIA1,LAMA2,QKI
8.216e-03	-4.80	CLb	smart domains	SM00030	2	1	9717	40	CLU
8.216e-03	-4.80	CLa	smart domains	SM00035	2	1	9717	40	CLU
8.268e-03	-4.80	G protein-coupled GABA receptor activity	molecular function	GO:0004965	3	1	18094	50	GABBR2
8.268e-03	-4.80	cysteine transmembrane transporter activity	molecular function	GO:0033229	3	1	18094	50	SLC1A2
8.268e-03	-4.80	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	molecular function	GO:0099583	3	1	18094	50	GRIA1
8.268e-03	-4.80	heparan sulfate 6-O-sulfotransferase activity	molecular function	GO:0017095	3	1	18094	50	HS6ST3
8.268e-03	-4.80	JUN kinase activity	molecular function	GO:0004705	3	1	18094	50	MAPK10
8.268e-03	-4.80	oncostatin-M receptor activity	molecular function	GO:0004924	3	1	18094	50	LIFR
8.295e-03	-4.79	endoplasmic reticulum lumen	cellular component	GO:0005788	312	4	19108	49	SPON1,CLU,CST3,SPARCL1
8.301e-03	-4.79	response to nerve growth factor	biological process	GO:1990089	52	2	18204	48	NTRK2,GRIA1
8.392e-03	-4.78	Neurotransmitter Release Cycle	REACTOME pathways	R-HSA-112310	51	2	10285	28	SLC1A2,SLC1A3
8.483e-03	-4.77	negative regulation of protein metabolic process	biological process	GO:0051248	893	7	18204	48	CST3,PTPRT,SPON1,DMD,CLU,QKI,NTRK2
8.483e-03	-4.77	monoatomic anion transport	biological process	GO:0006820	159	3	18204	48	SLC1A3,SLC1A2,GABRB1
8.507e-03	-4.77	NOS1 (nitric oxide synthase 1)	protein interactions	4842	54	2	19454	50	DMD,HS6ST3
8.567e-03	-4.76	-	gene3d domains	3.30.60.30	43	2	14470	47	SMOC1,SPARCL1
8.593e-03	-4.76	transport	biological process	GO:0006810	3615	17	18204	48	GPM6B,GABRB1,SLC1A2,GRIK1,GRIA4,DCLK1,NTRK2,SLC1A3,CLU,AQP4,GFAP,GRIA1,GRID2,GPM6A,CPE,ATP1A2,QKI
8.612e-03	-4.75	neutral amino acid transport	biological process	GO:0015804	53	2	18204	48	SLC1A2,SLC1A3
8.764e-03	-4.74	regulation of cell projection organization	biological process	GO:0031344	683	6	18204	48	GFAP,GRID2,NTRK2,GPM6A,DGKG,TNIK
8.782e-03	-4.74	CGMPKINASE	prints domains	PR00104	2	1	5227	23	PRKG1
8.917e-03	-4.72	INSYN1 (inhibitory synaptic factor 1)	protein interactions	388135	166	3	19454	50	DTNA,DMD,TNIK
9.109e-03	-4.70	response to light stimulus	biological process	GO:0009416	312	4	18204	48	MAPK10,SLC1A2,SLC1A3,ATP1A2
9.125e-03	-4.70	CSTL1 (cystatin like 1)	protein interactions	128817	56	2	19454	50	CPE,CLU
9.125e-03	-4.70	SEPTIN3 (septin 3)	protein interactions	55964	56	2	19454	50	PRKG1,GPM6A
9.129e-03	-4.70	cellular homeostasis	biological process	GO:0019725	689	6	18204	48	DMD,GRIA1,ATP1A2,AQP4,ZBTB20,SLC1A3
9.229e-03	-4.69	negative regulation of neuron apoptotic process	biological process	GO:0043524	164	3	18204	48	PTPRZ1,CLU,NTRK2
9.272e-03	-4.68	medullary_carcinoma	COSMIC cancer mutations	medullary_carcinoma	290	4	16828	48	PRKG1,GFAP,NRG3,SLC1A2
9.272e-03	-4.68	thyroid-carcinoma-medullary_carcinoma	COSMIC cancer mutations	thyroid-carcinoma-medullary_carcinoma	290	4	16828	48	NRG3,SLC1A2,PRKG1,GFAP
9.303e-03	-4.68	Prot_kinase_dom	interpro domains	IPR000719	480	5	18521	50	PRKG1,MAPK10,TNIK,NTRK2,DCLK1
9.344e-03	-4.67	positive regulation of developmental process	biological process	GO:0051094	1385	9	18204	48	NTRK2,QKI,SOX6,GPM6B,GFAP,LAMA2,SASH1,PTPRZ1,GRID2
9.391e-03	-4.67	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	46	16828	48	GFAP,QKI,CTNNA3,PPP2R2B,GPM6A,GPM6B,DPP6,CLU,LSAMP,MYO16,DMD,PDZRN4,SASH1,SLC1A3,PHYHIPL,NRG3,TNIK,GRIK1,GLIS3,CPE,NPAS3,LIFR,ZBTB20,DGKG,PCDH9,DCLK1,PRKG1,GABRB1,SOX6,DTNA,PTPRT,NTM,SMOC1,GABBR2,CTNND2,NTRK2,ATP1A2,SPARCL1,HS6ST3,GRIA4,LAMA2,GRIA1,GRID2,PTPRZ1,SPON1,SLC1A2
9.475e-03	-4.66	Ser/Thr_kinase_AS	interpro domains	IPR008271	308	4	18521	50	TNIK,DCLK1,MAPK10,PRKG1
9.564e-03	-4.65	side of membrane	cellular component	GO:0098552	715	6	19108	49	LSAMP,GFAP,AQP4,LIFR,NTM,DTNA
9.576e-03	-4.65	cardiac muscle cell action potential	biological process	GO:0086001	56	2	18204	48	DMD,ATP1A2
9.713e-03	-4.63	Reeler domain	gene3d domains	2.60.40.4060	3	1	14470	47	SPON1
9.713e-03	-4.63	Diacylglycerol kinase alpha	gene3d domains	1.10.238.110	3	1	14470	47	DGKG
9.713e-03	-4.63	-	gene3d domains	6.10.250.2510	3	1	14470	47	CTNNA3
9.813e-03	-4.62	large_cell_carcinoma	COSMIC cancer mutations	large_cell_carcinoma	849	7	16828	48	PTPRZ1,PRKG1,DCLK1,TNIK,NTRK2,LIFR,GABRB1
9.813e-03	-4.62	lung-carcinoma-large_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-large_cell_carcinoma	849	7	16828	48	NTRK2,TNIK,GABRB1,LIFR,PTPRZ1,DCLK1,PRKG1
9.840e-03	-4.62	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	23	16828	48	CTNNA3,PPP2R2B,QKI,PTPRT,GPM6B,CLU,LSAMP,GABBR2,DMD,CTNND2,PDZRN4,NTRK2,SPARCL1,SLC1A3,GRIA4,TNIK,GRIA1,PTPRZ1,NPAS3,LIFR,DGKG,PRKG1,DCLK1
9.840e-03	-4.62	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	23	16828	48	GRIA4,GRIA1,TNIK,PTPRZ1,LIFR,NPAS3,DGKG,PRKG1,DCLK1,GPM6B,PPP2R2B,CTNNA3,QKI,PTPRT,CLU,LSAMP,DMD,GABBR2,CTNND2,PDZRN4,SPARCL1,NTRK2,SLC1A3
9.871e-03	-4.62	cell-cell junction	cellular component	GO:0005911	513	5	19108	49	ATP1A2,CTNND2,CTNNA3,PCDH9,GRIA1
9.908e-03	-4.61	visual behavior	biological process	GO:0007632	57	2	18204	48	ATP1A2,SLC1A2
9.953e-03	-4.61	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	6	16828	48	TNIK,DCLK1,MYO16,PRKG1,LAMA2,QKI
1.005e-02	-4.60	PTPc	smart domains	SM00194	37	2	9717	40	PTPRT,PTPRZ1
1.005e-02	-4.60	GABA receptor activation	REACTOME pathways	R-HSA-977443	56	2	10285	28	GABRB1,GABBR2
1.009e-02	-4.60	VEGFA (vascular endothelial growth factor A)	protein interactions	7422	59	2	19454	50	PTPRZ1,CLU
1.013e-02	-4.59	SMCHD1 (structural maintenance of chromosomes flexible hinge domain containing 1)	protein interactions	23347	174	3	19454	50	DGKG,SOX6,PHYHIPL
1.017e-02	-4.59	protein phosphorylation	biological process	GO:0006468	503	5	18204	48	PRKG1,TNIK,DCLK1,NTRK2,MAPK10
1.017e-02	-4.59	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing	298	4	16828	48	CTNNA3,CTNND2,DCLK1,ATP1A2
1.022e-02	-4.58	syntrophin complex	cellular component	GO:0016013	4	1	19108	49	DMD
1.024e-02	-4.58	CENPS-CORT (CENPS-CORT readthrough)	protein interactions	100526739	4	1	19454	50	CTNNA3
1.024e-02	-4.58	CCDC126 (coiled-coil domain containing 126)	protein interactions	90693	4	1	19454	50	GPM6A
1.024e-02	-4.58	Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1)	protein interactions	15502	4	1	19454	50	GLIS3
1.024e-02	-4.58	IER5L (immediate early response 5 like)	protein interactions	389792	4	1	19454	50	PPP2R2B
1.024e-02	-4.58	regulation of sodium ion transmembrane transport	biological process	GO:1902305	58	2	18204	48	DMD,ATP1A2
1.030e-02	-4.58	REELIN	prosite domains	PS51019	3	1	12186	42	SPON1
1.037e-02	-4.57	neuron projection membrane	cellular component	GO:0032589	60	2	19108	49	SLC1A2,GRIA1
1.042e-02	-4.56	SNTB1 (syntrophin beta 1)	protein interactions	6641	60	2	19454	50	DMD,DTNA
1.051e-02	-4.56	oviduct epithelium development	biological process	GO:0035846	4	1	18204	48	CSMD1
1.051e-02	-4.56	regulation of collagen catabolic process	biological process	GO:0010710	4	1	18204	48	CST3
1.051e-02	-4.56	leukemia inhibitory factor signaling pathway	biological process	GO:0048861	4	1	18204	48	LIFR
1.051e-02	-4.56	regulation of amino acid uptake involved in synaptic transmission	biological process	GO:0051941	4	1	18204	48	ATP1A2
1.051e-02	-4.56	response to glycoside	biological process	GO:1903416	4	1	18204	48	ATP1A2
1.051e-02	-4.56	negative regulation of protein kinase C signaling	biological process	GO:0090038	4	1	18204	48	DGKG
1.051e-02	-4.56	oncostatin-M-mediated signaling pathway	biological process	GO:0038165	4	1	18204	48	LIFR
1.051e-02	-4.56	regulation of glutamate uptake involved in transmission of nerve impulse	biological process	GO:0051946	4	1	18204	48	ATP1A2
1.051e-02	-4.56	brain-derived neurotrophic factor receptor signaling pathway	biological process	GO:0031547	4	1	18204	48	NTRK2
1.051e-02	-4.56	positive regulation of inclusion body assembly	biological process	GO:0090261	4	1	18204	48	CLU
1.051e-02	-4.56	regulation of serotonin uptake	biological process	GO:0051611	4	1	18204	48	GPM6B
1.051e-02	-4.56	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	biological process	GO:0014809	4	1	18204	48	DMD
1.051e-02	-4.56	protein localization to secretory granule	biological process	GO:0033366	4	1	18204	48	CPE
1.051e-02	-4.56	positive regulation of mesenchymal stem cell differentiation	biological process	GO:2000741	4	1	18204	48	SOX6
1.051e-02	-4.56	trans-synaptic signaling by BDNF	biological process	GO:0099191	4	1	18204	48	NTRK2
1.059e-02	-4.55	circulatory system process	biological process	GO:0003013	508	5	18204	48	DMD,SLC1A2,SLC1A3,PRKG1,ATP1A2
1.076e-02	-4.53	PP2A_PR55	interpro domains	IPR000009	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	Alpha_catenin	interpro domains	IPR001033	4	1	18521	50	CTNNA3
1.076e-02	-4.53	PP2A_PR55_CS	interpro domains	IPR018067	4	1	18521	50	PPP2R2B
1.076e-02	-4.53	PRKG1 (protein kinase cGMP-dependent 1)	protein interactions	5592	61	2	19454	50	PRKG1,TNIK
1.076e-02	-4.53	CP (ceruloplasmin)	protein interactions	1356	61	2	19454	50	PPP2R2B,CLU
1.077e-02	-4.53	ERBB4 (erb-b2 receptor tyrosine kinase 4)	protein interactions	2066	178	3	19454	50	NTRK2,PTPRT,NRG3
1.093e-02	-4.52	regulation of smooth muscle contraction	biological process	GO:0006940	60	2	18204	48	PRKG1,ATP1A2
1.101e-02	-4.51	ciliary neurotrophic factor receptor activity	molecular function	GO:0004897	4	1	18094	50	LIFR
1.101e-02	-4.51	brain-derived neurotrophic factor binding	molecular function	GO:0048403	4	1	18094	50	NTRK2
1.106e-02	-4.50	bladder	COSMIC cancer mutations	bladder	14112	46	16828	48	PTPRZ1,GRID2,SPON1,GRIA4,LAMA2,GRIA1,SLC1A2,SMOC1,GABBR2,PTPRT,NTM,HS6ST3,CTNND2,SPARCL1,ATP1A2,NTRK2,LIFR,NPAS3,CPE,GLIS3,GRIK1,TNIK,NRG3,PRKG1,DCLK1,DTNA,SOX6,GABRB1,ZBTB20,PCDH9,DGKG,MYO16,LSAMP,DMD,GPM6B,GPM6A,QKI,CTNNA3,PPP2R2B,GFAP,DPP6,CLU,PHYHIPL,SLC1A3,PDZRN4,SASH1
1.106e-02	-4.50	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	46	16828	48	DMD,MYO16,LSAMP,CLU,DPP6,GPM6A,GPM6B,GFAP,QKI,PPP2R2B,CTNNA3,SLC1A3,PHYHIPL,SASH1,PDZRN4,LIFR,NPAS3,GLIS3,CPE,NRG3,GRIK1,TNIK,SOX6,GABRB1,DTNA,DCLK1,PRKG1,PCDH9,DGKG,ZBTB20,GABBR2,SMOC1,NTM,PTPRT,HS6ST3,SPARCL1,NTRK2,ATP1A2,CTNND2,SPON1,GRID2,PTPRZ1,GRIA1,GRIA4,LAMA2,SLC1A2
1.110e-02	-4.50	ZKSCAN1 (zinc finger with KRAB and SCAN domains 1)	protein interactions	7586	62	2	19454	50	QKI,PRKG1
1.118e-02	-4.49	phosphotransferase activity, alcohol group as acceptor	molecular function	GO:0016773	686	6	18094	50	TNIK,DCLK1,NTRK2,PRKG1,MAPK10,DGKG
1.121e-02	-4.49	EF_Hand_1_Ca_BS	interpro domains	IPR018247	172	3	18521	50	SPARCL1,DGKG,SMOC1
1.123e-02	-4.49	PRTYPHPHTASE	prints domains	PR00700	37	2	5227	23	PTPRT,PTPRZ1
1.143e-02	-4.47	human chr14q13.1	chromosome location	human chr14q13.1	6	1	26134	50	NPAS3
1.143e-02	-4.47	human chr4q34.2	chromosome location	human chr4q34.2	6	1	26134	50	GPM6A
1.144e-02	-4.47	DCAF16 (DDB1 and CUL4 associated factor 16)	protein interactions	54876	63	2	19454	50	DGKG,SMOC1
1.144e-02	-4.47	KCNA4 (potassium voltage-gated channel subfamily A member 4)	protein interactions	3739	63	2	19454	50	DMD,DTNA
1.161e-02	-4.46	GSN (gelsolin)	protein interactions	2934	183	3	19454	50	TNIK,DTNA,PPP2R2B
1.161e-02	-4.46	MAPK9 (mitogen-activated protein kinase 9)	protein interactions	5601	183	3	19454	50	GFAP,MAPK10,CLU
1.172e-02	-4.45	muscle structure development	biological process	GO:0061061	521	5	18204	48	LAMA2,SOX6,DMD,PRKG1,QKI
1.179e-02	-4.44	SYNC (syncoilin, intermediate filament protein)	protein interactions	81493	64	2	19454	50	DTNA,GFAP
1.179e-02	-4.44	PDZK1 (PDZ domain containing 1)	protein interactions	5174	64	2	19454	50	SLC1A3,GFAP
1.181e-02	-4.44	Tyr_Pase_cat	interpro domains	IPR003595	61	2	18521	50	PTPRZ1,PTPRT
1.183e-02	-4.44	KAZAL_2	prosite domains	PS51465	48	2	12186	42	SMOC1,SPARCL1
1.185e-02	-4.44	phosphorylation	biological process	GO:0016310	729	6	18204	48	MAPK10,PRKG1,TNIK,DGKG,NTRK2,DCLK1
1.187e-02	-4.43	lower_third	COSMIC cancer mutations	lower_third	7961	31	16828	48	SPON1,NPAS3,LIFR,PTPRZ1,GRID2,NRG3,CPE,GRIA1,LAMA2,GRIA4,SOX6,PRKG1,DCLK1,DGKG,PCDH9,ZBTB20,GABBR2,DMD,MYO16,DPP6,CTNNA3,QKI,PTPRT,GPM6B,PHYHIPL,ATP1A2,NTRK2,SASH1,CTNND2,PDZRN4,AQP4
1.205e-02	-4.42	primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	primitive_neuroectodermal_tumour-medulloblastoma	15350	48	16828	48	LIFR,NPAS3,CPE,GLIS3,TNIK,GRIK1,NRG3,DTNA,SOX6,GABRB1,PRKG1,DCLK1,PCDH9,DGKG,ZBTB20,DMD,MYO16,LSAMP,CST3,CLU,DPP6,GPM6B,GPM6A,CTNNA3,QKI,PPP2R2B,GFAP,PHYHIPL,SLC1A3,SASH1,PDZRN4,SPON1,PTPRZ1,GRID2,GRIA1,GRIA4,LAMA2,SLC1A2,GABBR2,SMOC1,NTM,PTPRT,HS6ST3,SPARCL1,ATP1A2,NTRK2,AQP4,CTNND2
1.215e-02	-4.41	HPX (hemopexin)	protein interactions	3263	65	2	19454	50	CLU,PPP2R2B
1.227e-02	-4.40	regulation of developmental process	biological process	GO:0050793	2540	13	18204	48	LAMA2,GPM6B,DGKG,NTRK2,PTPRZ1,CST3,GRID2,SASH1,GFAP,TNIK,SMOC1,SOX6,QKI
1.237e-02	-4.39	dendrite morphogenesis	biological process	GO:0048813	64	2	18204	48	CTNND2,DCLK1
1.274e-02	-4.36	positive regulation of synapse assembly	biological process	GO:0051965	65	2	18204	48	NTRK2,GRID2
1.276e-02	-4.36	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	49	CLU
1.276e-02	-4.36	kainate selective glutamate receptor complex	cellular component	GO:0032983	5	1	19108	49	GRIK1
1.279e-02	-4.36	ADCYAP1R1 (ADCYAP receptor type I)	protein interactions	117	5	1	19454	50	CLU
1.279e-02	-4.36	TRH (thyrotropin releasing hormone)	protein interactions	7200	5	1	19454	50	CPE
1.279e-02	-4.36	PPP1R17 (protein phosphatase 1 regulatory subunit 17)	protein interactions	10842	5	1	19454	50	PRKG1
1.279e-02	-4.36	Wwp2 (WW domain containing E3 ubiquitin protein ligase 2)	protein interactions	66894	5	1	19454	50	GLIS3
1.279e-02	-4.36	TAAR1 (trace amine associated receptor 1)	protein interactions	134864	5	1	19454	50	GRIK1
1.279e-02	-4.36	EPPIN (epididymal peptidase inhibitor)	protein interactions	57119	5	1	19454	50	CLU
1.279e-02	-4.36	RVS161 (amphiphysin-like protein RVS161)	protein interactions	850367	5	1	19454	50	GFAP
1.287e-02	-4.35	ARMC1 (armadillo repeat containing 1)	protein interactions	55156	67	2	19454	50	GPM6A,GPM6B
1.291e-02	-4.35	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	44	16828	48	PCDH9,DGKG,ZBTB20,DTNA,GABRB1,SOX6,PRKG1,DCLK1,GLIS3,GRIK1,TNIK,NRG3,LIFR,NPAS3,SASH1,PDZRN4,SLC1A3,CLU,DPP6,GPM6B,GPM6A,PPP2R2B,CTNNA3,QKI,GFAP,DMD,MYO16,CST3,LSAMP,SLC1A2,GRIA1,LAMA2,GRIA4,SPON1,PTPRZ1,GRID2,ATP1A2,NTRK2,CTNND2,HS6ST3,NTM,PTPRT,GABBR2,SMOC1
1.308e-02	-4.34	virilizing_syndrome_producing	COSMIC cancer mutations	virilizing_syndrome_producing	321	4	16828	48	ATP1A2,CTNNA3,CTNND2,DCLK1
1.312e-02	-4.33	cellular response to ammonium ion	biological process	GO:0071242	5	1	18204	48	GRIA1
1.312e-02	-4.33	neuron-glial cell signaling	biological process	GO:0150099	5	1	18204	48	GABBR2
1.312e-02	-4.33	positive regulation of amyloid fibril formation	biological process	GO:1905908	5	1	18204	48	CLU
1.312e-02	-4.33	amygdala development	biological process	GO:0021764	5	1	18204	48	ATP1A2
1.312e-02	-4.33	central nervous system myelin maintenance	biological process	GO:0032286	5	1	18204	48	CLU
1.312e-02	-4.33	negative regulation of glutamate secretion	biological process	GO:0014050	5	1	18204	48	PRKG1
1.312e-02	-4.33	ciliary neurotrophic factor-mediated signaling pathway	biological process	GO:0070120	5	1	18204	48	LIFR
1.312e-02	-4.33	spinal cord oligodendrocyte cell differentiation	biological process	GO:0021529	5	1	18204	48	SOX6
1.312e-02	-4.33	conditioned place preference	biological process	GO:1990708	5	1	18204	48	CSMD1
1.312e-02	-4.33	synaptic signaling via neuropeptide	biological process	GO:0099538	5	1	18204	48	NTRK2
1.312e-02	-4.33	L-alpha-amino acid transmembrane transport	biological process	GO:1902475	66	2	18204	48	SLC1A3,SLC1A2
1.313e-02	-4.33	Kinase-like_dom_sf	interpro domains	IPR011009	523	5	18521	50	MAPK10,PRKG1,NTRK2,TNIK,DCLK1
1.315e-02	-4.33	GABAARBETA	prints domains	PR01160	3	1	5227	23	GABRB1
1.315e-02	-4.33	JNKMAPKINASE	prints domains	PR01772	3	1	5227	23	MAPK10
1.315e-02	-4.33	GABABRECEPTR	prints domains	PR01176	3	1	5227	23	GABBR2
1.315e-02	-4.33	NTKRECEPTOR	prints domains	PR01939	3	1	5227	23	NTRK2
1.324e-02	-4.32	FAM162A (family with sequence similarity 162 member A)	protein interactions	26355	68	2	19454	50	CTNNA3,GPM6B
1.324e-02	-4.32	CADPS (calcium dependent secretion activator)	protein interactions	8618	68	2	19454	50	DMD,GPM6A
1.332e-02	-4.32	human chr4q21.3	chromosome location	human chr4q21.3	7	1	26134	50	MAPK10
1.332e-02	-4.32	human chr7q36.2	chromosome location	human chr7q36.2	7	1	26134	50	DPP6
1.332e-02	-4.32	human chr13q21.32	chromosome location	human chr13q21.32	7	1	26134	50	PCDH9
1.336e-02	-4.32	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma	323	4	16828	48	NTM,GRID2,PTPRZ1,MYO16
1.342e-02	-4.31	Laminin_I	pfam domains	PF06008	5	1	17795	48	LAMA2
1.342e-02	-4.31	Vinculin	pfam domains	PF01044	5	1	17795	48	CTNNA3
1.342e-02	-4.31	Protocadherin	pfam domains	PF08374	5	1	17795	48	PCDH9
1.342e-02	-4.31	Laminin_II	pfam domains	PF06009	5	1	17795	48	LAMA2
1.342e-02	-4.31	FOLN	pfam domains	PF09289	5	1	17795	48	SPARCL1
1.343e-02	-4.31	Laminin_aI	interpro domains	IPR009254	5	1	18521	50	LAMA2
1.343e-02	-4.31	Laminin_dom_II	interpro domains	IPR010307	5	1	18521	50	LAMA2
1.343e-02	-4.31	Vinculin/catenin	interpro domains	IPR006077	5	1	18521	50	CTNNA3
1.343e-02	-4.31	DCX/DCDC2-like	interpro domains	IPR049626	5	1	18521	50	DCLK1
1.343e-02	-4.31	Protocadherin	interpro domains	IPR013585	5	1	18521	50	PCDH9
1.343e-02	-4.31	Follistatin/Osteonectin_EGF	interpro domains	IPR015369	5	1	18521	50	SPARCL1
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.353e-02	-4.30	extracellular matrix binding	molecular function	GO:0050840	64	2	18094	50	SMOC1,SPARCL1
1.354e-02	-4.30	NGF-independant TRKA activation	REACTOME pathways	R-HSA-187024	5	1	10285	28	NTRK2
1.372e-02	-4.29	PR55_2	prosite domains	PS01025	4	1	12186	42	PPP2R2B
1.372e-02	-4.29	PR55_1	prosite domains	PS01024	4	1	12186	42	PPP2R2B
1.374e-02	-4.29	kainate selective glutamate receptor activity	molecular function	GO:0015277	5	1	18094	50	GRIK1
1.374e-02	-4.29	neurotrophin receptor activity	molecular function	GO:0005030	5	1	18094	50	NTRK2
1.381e-02	-4.28	lung-carcinoid-endocrine_tumour	COSMIC cancer mutations	lung-carcinoid-endocrine_tumour	502	5	16828	48	PRKG1,DCLK1,TNIK,NTRK2,SASH1
1.398e-02	-4.27	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	14	16828	48	GLIS3,DPP6,CTNNA3,PTPRT,LAMA2,SPON1,GABBR2,NPAS3,PTPRZ1,SPARCL1,CTNND2,PDZRN4,AQP4,SOX6
1.398e-02	-4.27	embryonal	COSMIC cancer mutations	embryonal	2659	14	16828	48	PTPRZ1,NPAS3,SPON1,GABBR2,PTPRT,CTNNA3,LAMA2,GLIS3,DPP6,SOX6,PDZRN4,CTNND2,AQP4,SPARCL1
1.399e-02	-4.27	MBD3L1 (methyl-CpG binding domain protein 3 like 1)	protein interactions	85509	70	2	19454	50	ZBTB20,CTNNA3
1.409e-02	-4.26	Pkinase	pfam domains	PF00069	347	4	17795	48	TNIK,MAPK10,DCLK1,PRKG1
1.418e-02	-4.26	skin-sole-malignant_melanoma	COSMIC cancer mutations	skin-sole-malignant_melanoma	5	1	16828	48	DMD
1.430e-02	-4.25	regulation of multicellular organismal development	biological process	GO:2000026	1484	9	18204	48	PTPRZ1,GRID2,SASH1,LAMA2,GFAP,GPM6B,QKI,NTRK2,SOX6
1.434e-02	-4.24	L-amino acid transmembrane transporter activity	molecular function	GO:0015179	66	2	18094	50	SLC1A3,SLC1A2
1.437e-02	-4.24	ANK2 (ankyrin 2)	protein interactions	287	71	2	19454	50	GPM6A,TNIK
1.449e-02	-4.23	Amyotrophic lateral sclerosis (ALS)	KEGG pathways	hsa05014	51	2	7161	26	GRIA1,SLC1A2
1.449e-02	-4.23	Amyotrophic lateral sclerosis (ALS)	KEGG pathways	ko05014	51	2	7161	26	GRIA1,SLC1A2
1.450e-02	-4.23	marginal_zone_lymphoma	COSMIC cancer mutations	marginal_zone_lymphoma	331	4	16828	48	NTM,MYO16,PTPRZ1,GRID2
1.458e-02	-4.23	pancreas-carcinoma	COSMIC cancer mutations	pancreas-carcinoma	14770	47	16828	48	SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,HS6ST3,NTM,PTPRT,GABBR2,SMOC1,SLC1A2,GRIA1,GRIA4,LAMA2,SPON1,GRID2,PTPRZ1,SASH1,PDZRN4,SLC1A3,PHYHIPL,DPP6,CLU,GPM6A,GPM6B,GFAP,PPP2R2B,CTNNA3,QKI,DMD,MYO16,CST3,LSAMP,PCDH9,DGKG,ZBTB20,SOX6,GABRB1,DCLK1,PRKG1,GLIS3,CPE,NRG3,TNIK,GRIK1,LIFR,NPAS3
1.467e-02	-4.22	cardiac conduction	biological process	GO:0061337	70	2	18204	48	CTNNA3,ATP1A2
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic	14773	47	16828	48	SASH1,PDZRN4,PHYHIPL,SLC1A3,CLU,DPP6,GPM6B,GPM6A,QKI,CTNNA3,PPP2R2B,GFAP,DMD,MYO16,CST3,LSAMP,PCDH9,DGKG,ZBTB20,DTNA,SOX6,GABRB1,PRKG1,DCLK1,CPE,GLIS3,GRIK1,TNIK,NRG3,LIFR,NPAS3,SPARCL1,ATP1A2,NTRK2,AQP4,CTNND2,HS6ST3,NTM,PTPRT,GABBR2,SMOC1,SLC1A2,GRIA1,LAMA2,GRIA4,PTPRZ1,GRID2
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	14773	47	16828	48	PHYHIPL,SLC1A3,PDZRN4,SASH1,LSAMP,CST3,MYO16,DMD,CTNNA3,PPP2R2B,QKI,GFAP,GPM6B,GPM6A,CLU,DPP6,PRKG1,DCLK1,DTNA,GABRB1,SOX6,ZBTB20,DGKG,PCDH9,NPAS3,LIFR,GRIK1,TNIK,NRG3,CPE,GLIS3,HS6ST3,CTNND2,AQP4,ATP1A2,NTRK2,SPARCL1,SMOC1,GABBR2,PTPRT,NTM,SLC1A2,PTPRZ1,GRID2,LAMA2,GRIA4,GRIA1
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma	14773	47	16828	48	DPP6,CLU,GPM6A,GPM6B,GFAP,QKI,PPP2R2B,CTNNA3,DMD,MYO16,LSAMP,CST3,SASH1,PDZRN4,SLC1A3,PHYHIPL,GLIS3,CPE,NRG3,GRIK1,TNIK,LIFR,NPAS3,PCDH9,DGKG,ZBTB20,SOX6,GABRB1,DTNA,DCLK1,PRKG1,NTM,PTPRT,GABBR2,SMOC1,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,HS6ST3,GRIA1,LAMA2,GRIA4,GRID2,PTPRZ1,SLC1A2
1.470e-02	-4.22	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	COSMIC cancer mutations	central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic	14773	47	16828	48	GRIA1,GRIA4,LAMA2,PTPRZ1,GRID2,SLC1A2,NTM,PTPRT,GABBR2,SMOC1,ATP1A2,NTRK2,SPARCL1,CTNND2,AQP4,HS6ST3,GRIK1,TNIK,NRG3,CPE,GLIS3,NPAS3,LIFR,DGKG,PCDH9,ZBTB20,DTNA,GABRB1,SOX6,PRKG1,DCLK1,CLU,DPP6,QKI,PPP2R2B,CTNNA3,GFAP,GPM6B,GPM6A,DMD,CST3,LSAMP,MYO16,SASH1,PDZRN4,PHYHIPL,SLC1A3
1.474e-02	-4.22	classic	COSMIC cancer mutations	classic	14774	47	16828	48	SLC1A2,GRIA1,LAMA2,GRIA4,GRID2,PTPRZ1,NTRK2,ATP1A2,SPARCL1,CTNND2,AQP4,HS6ST3,NTM,PTPRT,GABBR2,SMOC1,DGKG,PCDH9,ZBTB20,GABRB1,SOX6,DTNA,DCLK1,PRKG1,NRG3,GRIK1,TNIK,GLIS3,CPE,NPAS3,LIFR,SASH1,PDZRN4,SLC1A3,PHYHIPL,CLU,DPP6,GFAP,CTNNA3,QKI,PPP2R2B,GPM6A,GPM6B,DMD,CST3,LSAMP,MYO16
1.476e-02	-4.22	DPYSL3 (dihydropyrimidinase like 3)	protein interactions	1809	72	2	19454	50	TNIK,GPM6A
1.490e-02	-4.21	medulla	COSMIC cancer mutations	medulla	14778	47	16828	48	NTM,PTPRT,GABBR2,SMOC1,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,HS6ST3,GRIA1,GRIA4,LAMA2,GRID2,PTPRZ1,SLC1A2,DPP6,CLU,GPM6A,GPM6B,GFAP,PPP2R2B,QKI,CTNNA3,DMD,MYO16,CST3,LSAMP,SASH1,PDZRN4,SLC1A3,PHYHIPL,GLIS3,CPE,NRG3,GRIK1,TNIK,LIFR,NPAS3,PCDH9,DGKG,ZBTB20,SOX6,GABRB1,DTNA,DCLK1,PRKG1
1.495e-02	-4.20	desmoplastic	COSMIC cancer mutations	desmoplastic	14779	47	16828	48	GABBR2,SMOC1,NTM,PTPRT,HS6ST3,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,GRID2,PTPRZ1,GRIA1,LAMA2,GRIA4,SLC1A2,DMD,MYO16,CST3,LSAMP,CLU,DPP6,GPM6A,GPM6B,GFAP,PPP2R2B,QKI,CTNNA3,SLC1A3,PHYHIPL,SASH1,PDZRN4,LIFR,NPAS3,GLIS3,CPE,NRG3,TNIK,GRIK1,SOX6,GABRB1,DTNA,DCLK1,PRKG1,PCDH9,DGKG,ZBTB20
1.505e-02	-4.20	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	7	16828	48	MYO16,GRID2,LIFR,GABRB1,PPP2R2B,CTNNA3,CTNND2
1.510e-02	-4.19	Common Pathways Underlying Drug Addiction	WikiPathways	WP2636	42	2	5310	24	GRIA4,GRIA1
1.526e-02	-4.18	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	46	16828	48	GABRB1,SOX6,DTNA,DCLK1,PRKG1,PCDH9,DGKG,ZBTB20,LIFR,NPAS3,GLIS3,CPE,NRG3,GRIK1,TNIK,SLC1A3,SASH1,PDZRN4,DMD,MYO16,LSAMP,CST3,CLU,DPP6,GPM6A,GFAP,QKI,CTNNA3,PPP2R2B,SLC1A2,SPON1,GRID2,PTPRZ1,GRIA1,GRIA4,LAMA2,HS6ST3,SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,GABBR2,SMOC1,NTM,PTPRT
1.532e-02	-4.18	DRP2 (dystrophin related protein 2)	protein interactions	1821	6	1	19454	50	DTNA
1.532e-02	-4.18	DEFB116 (defensin beta 116)	protein interactions	245930	6	1	19454	50	HS6ST3
1.532e-02	-4.18	LBX2 (ladybird homeobox 2)	protein interactions	85474	6	1	19454	50	GFAP
1.532e-02	-4.18	Taok2 (TAO kinase 2)	protein interactions	381921	6	1	19454	50	CLU
1.532e-02	-4.18	Itch (itchy, E3 ubiquitin protein ligase)	protein interactions	16396	6	1	19454	50	GLIS3
1.532e-02	-4.18	Tiam2 (T cell lymphoma invasion and metastasis 2)	protein interactions	24001	6	1	19454	50	DTNA
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	LIF (LIF interleukin 6 family cytokine)	protein interactions	3976	6	1	19454	50	LIFR
1.532e-02	-4.18	SLC12A5 (solute carrier family 12 member 5)	protein interactions	57468	6	1	19454	50	GPM6A
1.532e-02	-4.18	TPPP3 (tubulin polymerization promoting protein family member 3)	protein interactions	51673	6	1	19454	50	PPP2R2B
1.532e-02	-4.18	CYRIA (CYFIP related Rac1 interactor A)	protein interactions	81553	6	1	19454	50	GPM6A
1.532e-02	-4.18	GRID2IP (Grid2 interacting protein)	protein interactions	392862	6	1	19454	50	GRID2
1.532e-02	-4.18	Rara (retinoic acid receptor, alpha)	protein interactions	19401	6	1	19454	50	MAPK10
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.548e-02	-4.17	regulation of extracellular matrix organization	biological process	GO:1903053	72	2	18204	48	CST3,LAMA2
1.556e-02	-4.16	intracellular signal transduction	biological process	GO:0035556	1505	9	18204	48	TNIK,PRKG1,DGKG,DMD,MAPK10,DCLK1,ATP1A2,NRG3,MYO16
1.560e-02	-4.16	axonogenesis	biological process	GO:0007409	366	4	18204	48	LAMA2,PTPRZ1,DCLK1,PRKG1
1.568e-02	-4.16	kinase activity	molecular function	GO:0016301	739	6	18094	50	TNIK,NTRK2,DCLK1,MAPK10,PRKG1,DGKG
1.572e-02	-4.15	ST14 (ST14 transmembrane serine protease matriptase)	protein interactions	6768	205	3	19454	50	SPON1,SMOC1,CPE
1.572e-02	-4.15	UTRN (utrophin)	protein interactions	7402	205	3	19454	50	DMD,DTNA,SASH1
1.572e-02	-4.15	ERBB4-ERBB4 signaling pathway	biological process	GO:0038138	6	1	18204	48	NRG3
1.572e-02	-4.15	intracellular water homeostasis	biological process	GO:0009992	6	1	18204	48	AQP4
1.572e-02	-4.15	regulation of protein autoubiquitination	biological process	GO:1902498	6	1	18204	48	SASH1
1.572e-02	-4.15	cellular response to histamine	biological process	GO:0071420	6	1	18204	48	GABRB1
1.572e-02	-4.15	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	biological process	GO:0086073	6	1	18204	48	CTNNA3
1.572e-02	-4.15	negative regulation of extracellular matrix disassembly	biological process	GO:0010716	6	1	18204	48	CST3
1.572e-02	-4.15	oviduct development	biological process	GO:0060066	6	1	18204	48	CSMD1
1.572e-02	-4.15	relaxation of vascular associated smooth muscle	biological process	GO:0060087	6	1	18204	48	PRKG1
1.572e-02	-4.15	gamma-aminobutyric acid biosynthetic process	biological process	GO:0009449	6	1	18204	48	SLC1A3
1.572e-02	-4.15	response to ammonium ion	biological process	GO:0060359	6	1	18204	48	GRIA1
1.572e-02	-4.15	positive regulation of synaptic transmission, cholinergic	biological process	GO:0032224	6	1	18204	48	LAMA2
1.572e-02	-4.15	mammary gland formation	biological process	GO:0060592	6	1	18204	48	NRG3
1.572e-02	-4.15	protein targeting to vacuole involved in autophagy	biological process	GO:0071211	6	1	18204	48	CLU
1.573e-02	-4.15	caecum	COSMIC cancer mutations	caecum	14248	46	16828	48	PDZRN4,SASH1,SLC1A3,GPM6A,QKI,CTNNA3,PPP2R2B,GFAP,CLU,DPP6,MYO16,CST3,LSAMP,DMD,ZBTB20,PCDH9,DGKG,PRKG1,DCLK1,DTNA,SOX6,GABRB1,CPE,GLIS3,GRIK1,TNIK,NRG3,LIFR,NPAS3,AQP4,CTNND2,SPARCL1,ATP1A2,NTRK2,HS6ST3,PTPRT,NTM,SMOC1,GABBR2,SLC1A2,GRIA4,LAMA2,GRIA1,PTPRZ1,GRID2,SPON1
1.576e-02	-4.15	Spinal Cord Injury	WikiPathways	WP2431	119	3	5310	24	PTPRZ1,GFAP,AQP4
1.587e-02	-4.14	neuromuscular junction	cellular component	GO:0031594	75	2	19108	49	LAMA2,GRIA1
1.588e-02	-4.14	vasculogenesis	biological process	GO:0001570	73	2	18204	48	QKI,NTRK2
1.594e-02	-4.14	HDAC9 (histone deacetylase 9)	protein interactions	9734	75	2	19454	50	MAPK10,GFAP
1.595e-02	-4.14	regulation of signaling	biological process	GO:0023051	3534	16	18204	48	DGKG,PTPRT,LAMA2,SLC1A3,CLU,NTRK2,GRIA4,GRIK1,NRG3,TNIK,GRID2,GRIA1,GFAP,SASH1,CTNND2,ATP1A2
1.604e-02	-4.13	scaffold protein binding	molecular function	GO:0097110	70	2	18094	50	GRIA1,GRID2
1.608e-02	-4.13	DPPIV_N	pfam domains	PF00930	6	1	17795	48	DPP6
1.608e-02	-4.13	TSP1_spondin	pfam domains	PF19028	6	1	17795	48	SPON1
1.609e-02	-4.13	TSP1_spondin_dom	interpro domains	IPR044004	6	1	18521	50	SPON1
1.609e-02	-4.13	GLI-like	interpro domains	IPR043359	6	1	18521	50	GLIS3
1.609e-02	-4.13	P-type_ATPase_IIC	interpro domains	IPR005775	6	1	18521	50	ATP1A2
1.609e-02	-4.13	Peptidase_S9B_N	interpro domains	IPR002469	6	1	18521	50	DPP6
1.623e-02	-4.12	Activation of TRKA receptors	REACTOME pathways	R-HSA-187015	6	1	10285	28	NTRK2
1.624e-02	-4.12	regulation of cell communication	biological process	GO:0010646	3541	16	18204	48	PTPRT,LAMA2,DGKG,GRIK1,GRIA4,NRG3,SLC1A3,CLU,NTRK2,GRIA1,GRID2,SASH1,GFAP,TNIK,CTNND2,ATP1A2
1.624e-02	-4.12	Protein-protein interactions at synapses	REACTOME pathways	R-HSA-6794362	72	2	10285	28	GRIA1,GRIA4
1.647e-02	-4.11	ciliary neurotrophic factor receptor binding	molecular function	GO:0005127	6	1	18094	50	LIFR
1.647e-02	-4.11	steroid hormone binding	molecular function	GO:1990239	6	1	18094	50	ATP1A2
1.647e-02	-4.11	beta-2 adrenergic receptor binding	molecular function	GO:0031698	6	1	18094	50	GRIA1
1.647e-02	-4.11	glutamate-gated calcium ion channel activity	molecular function	GO:0022849	6	1	18094	50	GRIA1
1.672e-02	-4.09	regulation of calcium ion transmembrane transporter activity	biological process	GO:1901019	75	2	18204	48	DMD,ATP1A2
1.701e-02	-4.07	bone-tibia-chondrosarcoma	COSMIC cancer mutations	bone-tibia-chondrosarcoma	70	2	16828	48	DMD,CPE
1.705e-02	-4.07	Tyr_Pase_AS	interpro domains	IPR016130	74	2	18521	50	PTPRT,PTPRZ1
1.721e-02	-4.06	regulation of neurogenesis	biological process	GO:0050767	377	4	18204	48	NTRK2,QKI,GFAP,PTPRZ1
1.744e-02	-4.05	regulation of heart contraction	biological process	GO:0008016	208	3	18204	48	CTNNA3,DMD,ATP1A2
1.746e-02	-4.05	Lactose Intolerance	SMPDB pathways	SMP0000458	12	1	1369	2	ATP1A2
1.746e-02	-4.05	Lactose Degradation	SMPDB pathways	SMP0000457	12	1	1369	2	ATP1A2
1.749e-02	-4.05	ALPHACATENIN	prints domains	PR00805	4	1	5227	23	CTNNA3
1.749e-02	-4.05	PP2APR55	prints domains	PR00600	4	1	5227	23	PPP2R2B
1.754e-02	-4.04	establishment of localization	biological process	GO:0051234	3887	17	18204	48	GPM6B,SLC1A3,CLU,AQP4,DCLK1,NTRK2,GRIK1,GRIA4,SLC1A2,GABRB1,GPM6A,GRIA1,GRID2,GFAP,QKI,ATP1A2,CPE
1.757e-02	-4.04	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	48	ATP1A2,GRIK1
1.757e-02	-4.04	neural retina development	biological process	GO:0003407	77	2	18204	48	GPM6A,NTRK2
1.757e-02	-4.04	regulation of organic acid transport	biological process	GO:0032890	77	2	18204	48	ATP1A2,PRKG1
1.759e-02	-4.04	KRTAP3-2 (keratin associated protein 3-2)	protein interactions	83897	79	2	19454	50	NTM,GFAP
1.759e-02	-4.04	STMN2 (stathmin 2)	protein interactions	11075	79	2	19454	50	CTNNA3,MAPK10
1.761e-02	-4.04	protein serine kinase activity	molecular function	GO:0106310	362	4	18094	50	DCLK1,MAPK10,TNIK,PRKG1
1.782e-02	-4.03	G protein-coupled receptor dimeric complex	cellular component	GO:0038037	7	1	19108	49	GABBR2
1.786e-02	-4.03	ABCC12 (ATP binding cassette subfamily C member 12)	protein interactions	94160	7	1	19454	50	NPAS3
1.786e-02	-4.03	CYP4F8 (cytochrome P450 family 4 subfamily F member 8)	protein interactions	11283	7	1	19454	50	CLU
1.786e-02	-4.03	C7 (complement C7)	protein interactions	730	7	1	19454	50	CLU
1.786e-02	-4.03	Dlgap4 (DLG associated protein 4)	protein interactions	228836	7	1	19454	50	DMD
1.786e-02	-4.03	CDH10 (cadherin 10)	protein interactions	1008	7	1	19454	50	CTNNA3
1.786e-02	-4.03	CDH24 (cadherin 24)	protein interactions	64403	7	1	19454	50	CTNNA3
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	GRIK3 (glutamate ionotropic receptor kainate type subunit 3)	protein interactions	2899	7	1	19454	50	GRIK1
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	C8B (complement C8 beta chain)	protein interactions	732	7	1	19454	50	CLU
1.786e-02	-4.03	SLC16A5 (solute carrier family 16 member 5)	protein interactions	9121	7	1	19454	50	PTPRZ1
1.786e-02	-4.03	SOAT2 (sterol O-acyltransferase 2)	protein interactions	8435	7	1	19454	50	CLU
1.786e-02	-4.03	Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)	protein interactions	75788	7	1	19454	50	GLIS3
1.793e-02	-4.02	large_cell	COSMIC cancer mutations	large_cell	14845	47	16828	48	SASH1,PDZRN4,SLC1A3,PHYHIPL,CLU,DPP6,GFAP,CTNNA3,QKI,PPP2R2B,GPM6A,GPM6B,DMD,CST3,LSAMP,MYO16,DGKG,PCDH9,ZBTB20,SOX6,GABRB1,DTNA,DCLK1,PRKG1,NRG3,TNIK,GRIK1,GLIS3,CPE,NPAS3,LIFR,NTRK2,ATP1A2,SPARCL1,CTNND2,AQP4,HS6ST3,NTM,PTPRT,GABBR2,SMOC1,SLC1A2,GRIA1,GRIA4,LAMA2,GRID2,PTPRZ1
1.795e-02	-4.02	acute_lymphoblastic_T_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_T_cell_leukaemia	739	6	16828	48	SASH1,SOX6,GABRB1,GRIA1,CTNNA3,PTPRT
1.795e-02	-4.02	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia	739	6	16828	48	PTPRT,CTNNA3,GRIA1,SASH1,SOX6,GABRB1
1.801e-02	-4.02	TMED7 (transmembrane p24 trafficking protein 7)	protein interactions	51014	80	2	19454	50	GPM6A,SMOC1
1.801e-02	-4.02	TRIM9 (tripartite motif containing 9)	protein interactions	114088	80	2	19454	50	MYO16,GFAP
1.801e-02	-4.02	intracellular chemical homeostasis	biological process	GO:0055082	581	5	18204	48	GRIA1,ATP1A2,SLC1A3,AQP4,ZBTB20
1.827e-02	-4.00	myosin binding	molecular function	GO:0017022	75	2	18094	50	DMD,GRIA1
1.832e-02	-4.00	chaperone-mediated autophagy	biological process	GO:0061684	7	1	18204	48	CLU
1.832e-02	-4.00	relaxation of smooth muscle	biological process	GO:0044557	7	1	18204	48	PRKG1
1.832e-02	-4.00	positive regulation of long-term synaptic depression	biological process	GO:1900454	7	1	18204	48	GRID2
1.832e-02	-4.00	regulation of skeletal muscle contraction by calcium ion signaling	biological process	GO:0014722	7	1	18204	48	DMD
1.832e-02	-4.00	mammary gland branching involved in pregnancy	biological process	GO:0060745	7	1	18204	48	CSMD1
1.832e-02	-4.00	response to fungicide	biological process	GO:0060992	7	1	18204	48	GRIA1
1.832e-02	-4.00	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	48	QKI
1.832e-02	-4.00	cerebellar granule cell differentiation	biological process	GO:0021707	7	1	18204	48	GRID2
1.832e-02	-4.00	interneuron migration from the subpallium to the cortex	biological process	GO:0021830	7	1	18204	48	NRG3
1.832e-02	-4.00	cerebellar granular layer formation	biological process	GO:0021684	7	1	18204	48	GRID2
1.832e-02	-4.00	regulation of testosterone biosynthetic process	biological process	GO:2000224	7	1	18204	48	PRKG1
1.832e-02	-4.00	regulation of oligodendrocyte progenitor proliferation	biological process	GO:0070445	7	1	18204	48	PTPRZ1
1.832e-02	-4.00	cardiac muscle cell-cardiac muscle cell adhesion	biological process	GO:0086042	7	1	18204	48	CTNNA3
1.843e-02	-3.99	KLHL15 (kelch like family member 15)	protein interactions	80311	81	2	19454	50	PPP2R2B,DCLK1
1.844e-02	-3.99	regulation of glial cell differentiation	biological process	GO:0045685	79	2	18204	48	QKI,PTPRZ1
1.850e-02	-3.99	Viral myocarditis	KEGG pathways	hsa05416	58	2	7161	26	DMD,LAMA2
1.865e-02	-3.98	Protein_kinase_ATP_BS	interpro domains	IPR017441	377	4	18521	50	NTRK2,TNIK,DCLK1,PRKG1
1.873e-02	-3.98	Filament_head	pfam domains	PF04732	7	1	17795	48	GFAP
1.875e-02	-3.98	Intermed_filament_DNA-bd	interpro domains	IPR006821	7	1	18521	50	GFAP
1.875e-02	-3.98	Hematopoietin_rcpt_Gp130_CS	interpro domains	IPR003529	7	1	18521	50	LIFR
1.875e-02	-3.98	Plakophilin/d_Catenin	interpro domains	IPR028435	7	1	18521	50	CTNND2
1.875e-02	-3.98	Alpha-catenin/vinculin-like_sf	interpro domains	IPR036723	7	1	18521	50	CTNNA3
1.875e-02	-3.98	Aquaporin_transptr	interpro domains	IPR034294	7	1	18521	50	AQP4
1.884e-02	-3.97	extracellular region	cellular component	GO:0005576	4350	18	19108	49	TNIK,CST3,GRIA1,NRG3,NTM,LSAMP,LAMA2,PTPRZ1,SPON1,SPARCL1,LIFR,GRIA4,AQP4,CPE,CLU,GPM6A,ATP1A2,SMOC1
1.885e-02	-3.97	heparan sulfate biosynthesis (late stages)	BIOCYC pathways	META_PWY-6558	17	1	902	1	HS6ST3
1.886e-02	-3.97	GINM1 (glycosylated integral membrane protein 1)	protein interactions	116254	82	2	19454	50	SMOC1,CLU
1.891e-02	-3.97	Trehalose Degradation	SMPDB pathways	SMP0000467	13	1	1369	2	ATP1A2
1.897e-02	-3.96	human chr9p24.2	chromosome location	human chr9p24.2	10	1	26134	50	GLIS3
1.905e-02	-3.96	kidney-Wilms_tumour	COSMIC cancer mutations	kidney-Wilms_tumour	545	5	16828	48	DCLK1,MYO16,PRKG1,NTRK2,TNIK
1.918e-02	-3.95	leg	COSMIC cancer mutations	leg	969	7	16828	48	NRG3,NTM,PTPRT,PTPRZ1,ZBTB20,LAMA2,PRKG1
1.919e-02	-3.95	P-type sodium transporter activity	molecular function	GO:0008554	7	1	18094	50	ATP1A2
1.919e-02	-3.95	P-type sodium:potassium-exchanging transporter activity	molecular function	GO:0005391	7	1	18094	50	ATP1A2
1.919e-02	-3.95	mitogen-activated protein kinase p38 binding	molecular function	GO:0048273	7	1	18094	50	PRKG1
1.919e-02	-3.95	LBD domain binding	molecular function	GO:0050693	7	1	18094	50	SPON1
1.919e-02	-3.95	Wilms_tumour	COSMIC cancer mutations	Wilms_tumour	546	5	16828	48	DCLK1,PRKG1,MYO16,NTRK2,TNIK
1.933e-02	-3.95	Single helix bin	gene3d domains	1.20.5.490	6	1	14470	47	PRKG1
1.933e-02	-3.95	Dipeptidylpeptidase IV, N-terminal domain	gene3d domains	2.140.10.30	6	1	14470	47	DPP6
1.939e-02	-3.94	PSEN1 (presenilin 1)	protein interactions	5663	222	3	19454	50	GFAP,DTNA,CTNND2
1.950e-02	-3.94	regulation of cell junction assembly	biological process	GO:1901888	217	3	18204	48	NTRK2,GRID2,GPM6B
1.966e-02	-3.93	eye-uveal_tract-malignant_melanoma-spindle	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-spindle	363	4	16828	48	GRIA1,PCDH9,CPE,CTNND2
1.974e-02	-3.93	DCX (doublecortin)	protein interactions	1641	84	2	19454	50	GPM6A,DCLK1
1.974e-02	-3.93	PSEN2 (presenilin 2)	protein interactions	5664	84	2	19454	50	GFAP,CTNND2
1.983e-02	-3.92	signaling receptor binding	molecular function	GO:0005102	1493	9	18094	50	CLU,GFAP,CPE,NRG3,LIFR,GABRB1,GRIA1,PTPRZ1,LAMA2
2.015e-02	-3.90	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	5	16828	48	CTNNA3,PTPRT,GRIA4,GRIK1,GRIA1
2.018e-02	-3.90	CCND3 (cyclin D3)	protein interactions	896	85	2	19454	50	CLU,QKI
2.021e-02	-3.90	response to mechanical stimulus	biological process	GO:0009612	220	3	18204	48	ATP1A2,SLC1A3,DMD
2.023e-02	-3.90	regulation of amine transport	biological process	GO:0051952	83	2	18204	48	ATP1A2,PRKG1
2.023e-02	-3.90	cardiac muscle contraction	biological process	GO:0060048	83	2	18204	48	ATP1A2,DMD
2.034e-02	-3.90	spherical high-density lipoprotein particle	cellular component	GO:0034366	8	1	19108	49	CLU
2.038e-02	-3.89	GRIK4 (glutamate ionotropic receptor kainate type subunit 4)	protein interactions	2900	8	1	19454	50	GRIK1
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.038e-02	-3.89	ZNF662 (zinc finger protein 662)	protein interactions	389114	8	1	19454	50	CTNNA3
2.038e-02	-3.89	CCK (cholecystokinin)	protein interactions	885	8	1	19454	50	CPE
2.038e-02	-3.89	UBALD2 (UBA like domain containing 2)	protein interactions	283991	8	1	19454	50	GFAP
2.038e-02	-3.89	NKAIN3 (sodium/potassium transporting ATPase interacting 3)	protein interactions	286183	8	1	19454	50	GFAP
2.038e-02	-3.89	CNIH2 (cornichon family AMPA receptor auxiliary protein 2)	protein interactions	254263	8	1	19454	50	GRIA1
2.038e-02	-3.89	Chmp2a (charged multivesicular body protein 2A)	protein interactions	68953	8	1	19454	50	CLU
2.056e-02	-3.88	organic anion transport	biological process	GO:0015711	398	4	18204	48	NTRK2,SLC1A3,GFAP,SLC1A2
2.058e-02	-3.88	lung-left_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_upper_lobe-carcinoma-adenocarcinoma	556	5	16828	48	PRKG1,CTNND2,LIFR,SOX6,NTRK2
2.062e-02	-3.88	solute:sodium symporter activity	molecular function	GO:0015370	80	2	18094	50	SLC1A2,SLC1A3
2.069e-02	-3.88	L-amino acid transport	biological process	GO:0015807	84	2	18204	48	SLC1A2,SLC1A3
2.069e-02	-3.88	peripheral nervous system development	biological process	GO:0007422	84	2	18204	48	NTRK2,LAMA2
2.069e-02	-3.88	regulation of release of sequestered calcium ion into cytosol	biological process	GO:0051279	84	2	18204	48	DMD,ATP1A2
2.069e-02	-3.88	regulation of sodium ion transport	biological process	GO:0002028	84	2	18204	48	ATP1A2,DMD
2.079e-02	-3.87	Transferase(Phosphotransferase) domain 1	gene3d domains	1.10.510.10	490	5	14470	47	NTRK2,DCLK1,PRKG1,MAPK10,TNIK
2.087e-02	-3.87	left_upper_lobe	COSMIC cancer mutations	left_upper_lobe	558	5	16828	48	PRKG1,CTNND2,SOX6,LIFR,NTRK2
2.090e-02	-3.87	gamma-aminobutyric acid metabolic process	biological process	GO:0009448	8	1	18204	48	SLC1A3
2.090e-02	-3.87	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	biological process	GO:1990264	8	1	18204	48	PTPRT
2.090e-02	-3.87	ERBB4 signaling pathway	biological process	GO:0038130	8	1	18204	48	NRG3
2.090e-02	-3.87	protein import	biological process	GO:0017038	8	1	18204	48	CLU
2.090e-02	-3.87	regulation of chaperone-mediated autophagy	biological process	GO:1904714	8	1	18204	48	GFAP
2.090e-02	-3.87	insulin processing	biological process	GO:0030070	8	1	18204	48	CPE
2.090e-02	-3.87	regulation of synaptic transmission, cholinergic	biological process	GO:0032222	8	1	18204	48	LAMA2
2.090e-02	-3.87	regulation of L-glutamate import across plasma membrane	biological process	GO:0002036	8	1	18204	48	ATP1A2
2.090e-02	-3.87	negative regulation of peptidyl-cysteine S-nitrosylation	biological process	GO:1902083	8	1	18204	48	DMD
2.100e-02	-3.86	cellular process	biological process	GO:0009987	14996	45	18204	48	DGKG,LAMA2,LIFR,GRIA4,GABRB1,PPP2R2B,NTM,PTPRZ1,GRID2,LSAMP,CTNND2,QKI,PCDH9,PTPRT,GRIK1,TNIK,MAPK10,GFAP,ZBTB20,HS6ST3,DPP6,AQP4,CLU,GLIS3,SLC1A2,NRG3,GPM6A,CST3,GRIA1,CTNNA3,SPON1,SMOC1,MYO16,GPM6B,DMD,SLC1A3,NTRK2,DCLK1,GABBR2,SPARCL1,PRKG1,DTNA,ATP1A2,SOX6,CPE
2.106e-02	-3.86	heparan sulfate biosynthesis (late stages)	BIOCYC pathways	HUMAN_PWY-6558	19	1	902	1	HS6ST3
2.108e-02	-3.86	PROTEIN_KINASE_ST	prosite domains	PS00108	308	4	12186	42	DCLK1,PRKG1,TNIK,MAPK10
2.110e-02	-3.86	protein kinase activity	molecular function	GO:0004672	577	5	18094	50	NTRK2,DCLK1,MAPK10,TNIK,PRKG1
2.127e-02	-3.85	DST (dystonin)	protein interactions	667	230	3	19454	50	ATP1A2,TNIK,NTRK2
2.130e-02	-3.85	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma	561	5	16828	48	DCLK1,MYO16,NTRK2,TNIK,LIFR
2.133e-02	-3.85	haematopoietic_and_lymphoid_tissue	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue	14368	46	16828	48	NRG3,GRIK1,TNIK,GLIS3,GRIA1,CPE,LAMA2,GRIA4,NPAS3,SPON1,LIFR,GRID2,PTPRZ1,DGKG,PCDH9,ZBTB20,SLC1A2,SOX6,GABRB1,DTNA,DCLK1,PRKG1,CLU,DPP6,NTM,GFAP,PTPRT,PPP2R2B,CTNNA3,QKI,GPM6A,GABBR2,DMD,LSAMP,SMOC1,MYO16,NTRK2,ATP1A2,SASH1,SPARCL1,PDZRN4,CTNND2,AQP4,SLC1A3,PHYHIPL,HS6ST3
2.138e-02	-3.85	DCX	pfam domains	PF03607	8	1	17795	48	DCLK1
2.138e-02	-3.85	Laminin_B	pfam domains	PF00052	8	1	17795	48	LAMA2
2.140e-02	-3.84	Laminin_IV	interpro domains	IPR000034	8	1	18521	50	LAMA2
2.157e-02	-3.84	FYN (FYN proto-oncogene, Src family tyrosine kinase)	protein interactions	2534	414	4	19454	50	CTNNA3,CTNND2,PTPRZ1,NTRK2
2.186e-02	-3.82	EF_HAND_1	prosite domains	PS00018	174	3	12186	42	SPARCL1,DGKG,SMOC1
2.190e-02	-3.82	glutamate binding	molecular function	GO:0016595	8	1	18094	50	SLC1A3
2.190e-02	-3.82	P-type potassium transmembrane transporter activity	molecular function	GO:0008556	8	1	18094	50	ATP1A2
2.190e-02	-3.82	sodium ion binding	molecular function	GO:0031402	8	1	18094	50	ATP1A2
2.190e-02	-3.82	cyclic nucleotide-dependent protein kinase activity	molecular function	GO:0004690	8	1	18094	50	PRKG1
2.199e-02	-3.82	intracellular signaling cassette	biological process	GO:0141124	837	6	18204	48	ATP1A2,PRKG1,TNIK,MYO16,DMD,MAPK10
2.199e-02	-3.82	PLEKHA2 (pleckstrin homology domain containing A2)	protein interactions	59339	89	2	19454	50	DTNA,DMD
2.209e-02	-3.81	associative learning	biological process	GO:0008306	87	2	18204	48	ATP1A2,CSMD1
2.244e-02	-3.80	stomach	COSMIC cancer mutations	stomach	15550	48	16828	48	HS6ST3,NTRK2,ATP1A2,SPARCL1,CTNND2,AQP4,GABBR2,SMOC1,NTM,PTPRT,SLC1A2,SPON1,GRID2,PTPRZ1,GRIA1,GRIA4,LAMA2,SLC1A3,PHYHIPL,SASH1,PDZRN4,DMD,LSAMP,CST3,MYO16,DPP6,CLU,GFAP,CTNNA3,QKI,PPP2R2B,GPM6A,GPM6B,GABRB1,SOX6,DTNA,DCLK1,PRKG1,DGKG,PCDH9,ZBTB20,NPAS3,LIFR,NRG3,TNIK,GRIK1,GLIS3,CPE
2.246e-02	-3.80	SEMG1 (semenogelin 1)	protein interactions	6406	90	2	19454	50	PPP2R2B,CLU
2.249e-02	-3.79	MARK3 (microtubule affinity regulating kinase 3)	protein interactions	4140	235	3	19454	50	DTNA,PPP2R2B,NTRK2
2.251e-02	-3.79	lung-carcinoma-bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-bronchioloalveolar_adenocarcinoma	778	6	16828	48	NTRK2,TNIK,DCLK1,GRIA4,PRKG1,CTNND2
2.251e-02	-3.79	bronchioloalveolar_adenocarcinoma	COSMIC cancer mutations	bronchioloalveolar_adenocarcinoma	778	6	16828	48	GRIA4,PRKG1,DCLK1,CTNND2,TNIK,NTRK2
2.260e-02	-3.79	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	48	QKI
2.260e-02	-3.79	Tyr_Pase_dom	interpro domains	IPR000387	86	2	18521	50	PTPRZ1,PTPRT
2.263e-02	-3.79	Synaptic Vesicle Pathway	WikiPathways	WP2267	52	2	5310	24	SLC1A3,ATP1A2
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.272e-02	-3.78	human chr6q22.33	chromosome location	human chr6q22.33	12	1	26134	50	LAMA2
2.285e-02	-3.78	fascia adherens	cellular component	GO:0005916	9	1	19108	49	CTNNA3
2.290e-02	-3.78	PI3 (peptidase inhibitor 3)	protein interactions	5266	9	1	19454	50	PPP2R2B
2.290e-02	-3.78	IER5 (immediate early response 5)	protein interactions	51278	9	1	19454	50	PPP2R2B
2.290e-02	-3.78	SOBP (sine oculis binding protein homolog)	protein interactions	55084	9	1	19454	50	SOX6
2.290e-02	-3.78	LSB3 (Lsb3p)	protein interactions	850580	9	1	19454	50	GFAP
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	LOC102724023 (glutamine amidotransferase class 1 domain containing 3B)	protein interactions	102724023	9	1	19454	50	PHYHIPL
2.292e-02	-3.78	NEIL3 (nei like DNA glycosylase 3)	protein interactions	55247	91	2	19454	50	QKI,GFAP
2.294e-02	-3.77	regulation of cellular component organization	biological process	GO:0051128	2455	12	18204	48	GPM6B,LAMA2,GFAP,PTPRT,GRID2,CST3,GPM6A,TNIK,DGKG,NRG3,NTRK2,CLU
2.296e-02	-3.77	response to external stimulus	biological process	GO:0009605	1882	10	18204	48	NRG3,ATP1A2,DCLK1,AQP4,SLC1A3,CLU,CSMD1,DMD,GRID2,GPM6A
2.299e-02	-3.77	CAMK2A (calcium/calmodulin dependent protein kinase II alpha)	protein interactions	815	237	3	19454	50	GFAP,GRIA1,GPM6A
2.305e-02	-3.77	cellular response to amino acid stimulus	biological process	GO:0071230	89	2	18204	48	NTRK2,GRIA1
2.308e-02	-3.77	FN3	smart domains	SM00060	149	3	9717	40	PTPRZ1,LIFR,PTPRT
2.329e-02	-3.76	basement membrane	cellular component	GO:0005604	92	2	19108	49	LAMA2,SMOC1
2.339e-02	-3.76	ADGRG5 (adhesion G protein-coupled receptor G5)	protein interactions	221188	92	2	19454	50	GPM6B,GPM6A
2.341e-02	-3.75	upper_aerodigestive_tract-carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-carcinoma	383	4	16828	48	DCLK1,NTRK2,TNIK,LIFR
2.341e-02	-3.75	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma	383	4	16828	48	DCLK1,LIFR,TNIK,NTRK2
2.341e-02	-3.75	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma	383	4	16828	48	DCLK1,LIFR,NTRK2,TNIK
2.341e-02	-3.75	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma	383	4	16828	48	DCLK1,NTRK2,TNIK,LIFR
2.341e-02	-3.75	salivary_gland-carcinoma	COSMIC cancer mutations	salivary_gland-carcinoma	383	4	16828	48	DCLK1,NTRK2,TNIK,LIFR
2.348e-02	-3.75	RANBP9 (RAN binding protein 9)	protein interactions	10048	425	4	19454	50	SPON1,NTRK2,TNIK,GRIK1
2.349e-02	-3.75	macrophage proliferation	biological process	GO:0061517	9	1	18204	48	CLU
2.349e-02	-3.75	negative regulation of striated muscle contraction	biological process	GO:0045988	9	1	18204	48	ATP1A2
2.349e-02	-3.75	negative regulation of neurotransmitter transport	biological process	GO:0051589	9	1	18204	48	GPM6B
2.349e-02	-3.75	cerebellar granular layer morphogenesis	biological process	GO:0021683	9	1	18204	48	GRID2
2.349e-02	-3.75	microglial cell proliferation	biological process	GO:0061518	9	1	18204	48	CLU
2.380e-02	-3.74	PROTEIN_KINASE_DOM	prosite domains	PS50011	480	5	12186	42	NTRK2,DCLK1,PRKG1,TNIK,MAPK10
2.387e-02	-3.74	parotid	COSMIC cancer mutations	parotid	578	5	16828	48	MYO16,DCLK1,TNIK,NTRK2,LIFR
2.388e-02	-3.73	HEMATOPO_REC_L_F2	prosite domains	PS01353	7	1	12186	42	LIFR
2.400e-02	-3.73	spindle	COSMIC cancer mutations	spindle	386	4	16828	48	GRIA1,CPE,PCDH9,CTNND2
2.402e-02	-3.73	Peptidase_S9	pfam domains	PF00326	9	1	17795	48	DPP6
2.404e-02	-3.73	Fol_N	interpro domains	IPR003645	9	1	18521	50	SPARCL1
2.404e-02	-3.73	Prot_inh_cystat_CS	interpro domains	IPR018073	9	1	18521	50	CST3
2.404e-02	-3.73	Peptidase_S9	interpro domains	IPR001375	9	1	18521	50	DPP6
2.404e-02	-3.73	Doublecortin_dom	interpro domains	IPR003533	9	1	18521	50	DCLK1
2.425e-02	-3.72	Terminal pathway of complement	REACTOME pathways	R-HSA-166665	9	1	10285	28	CLU
2.435e-02	-3.72	TTR (transthyretin)	protein interactions	7276	94	2	19454	50	CLU,CTNND2
2.450e-02	-3.71	upper_arm	COSMIC cancer mutations	upper_arm	582	5	16828	48	GRIK1,GRIA1,PTPRT,CTNNA3,GRIA4
2.459e-02	-3.71	human chr13q33.3	chromosome location	human chr13q33.3	13	1	26134	50	MYO16
2.460e-02	-3.70	delta-catenin binding	molecular function	GO:0070097	9	1	18094	50	PTPRT
2.469e-02	-3.70	Ion Channels and Their Functional Role in Vascular Endothelium	SMPDB pathways	SMP0063778	17	1	1369	2	PRKG1
2.479e-02	-3.70	DDX31 (DEAD-box helicase 31)	protein interactions	64794	244	3	19454	50	CLU,CST3,PRKG1
2.479e-02	-3.70	muscle contraction	biological process	GO:0006936	238	3	18204	48	DTNA,DMD,ATP1A2
2.485e-02	-3.70	response to radiation	biological process	GO:0009314	422	4	18204	48	ATP1A2,SLC1A3,SLC1A2,MAPK10
2.486e-02	-3.69	enzyme binding	molecular function	GO:0019899	2086	11	18094	50	GFAP,CLU,NRG3,MYO16,PRKG1,NTRK2,DMD,PTPRT,SASH1,GRIA1,CST3
2.494e-02	-3.69	Epithelial cell signaling in Helicobacter pylori infection	KEGG pathways	hsa05120	68	2	7161	26	PTPRZ1,MAPK10
2.494e-02	-3.69	Epithelial cell signaling in Helicobacter pylori infection	KEGG pathways	ko05120	68	2	7161	26	MAPK10,PTPRZ1
2.494e-02	-3.69	Amphetamine addiction	KEGG pathways	hsa05031	68	2	7161	26	GRIA4,GRIA1
2.494e-02	-3.69	Amphetamine addiction	KEGG pathways	ko05031	68	2	7161	26	GRIA4,GRIA1
2.518e-02	-3.68	oesophagus	COSMIC cancer mutations	oesophagus	14970	47	16828	48	SOX6,GABRB1,PRKG1,DCLK1,PCDH9,DGKG,ZBTB20,LIFR,NPAS3,CPE,GLIS3,TNIK,GRIK1,NRG3,PHYHIPL,SLC1A3,SASH1,PDZRN4,DMD,MYO16,LSAMP,CST3,DPP6,CLU,GPM6B,GPM6A,CTNNA3,PPP2R2B,QKI,GFAP,SLC1A2,SPON1,PTPRZ1,GRID2,GRIA1,LAMA2,GRIA4,HS6ST3,SPARCL1,ATP1A2,NTRK2,AQP4,CTNND2,GABBR2,SMOC1,NTM,PTPRT
2.532e-02	-3.68	E7 (E7 protein)	protein interactions	1489369	96	2	19454	50	QKI,SASH1
2.536e-02	-3.67	perineuronal net	cellular component	GO:0072534	10	1	19108	49	PTPRZ1
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	Smurf2 (SMAD specific E3 ubiquitin protein ligase 2)	protein interactions	66313	10	1	19454	50	GLIS3
2.541e-02	-3.67	SLC8A2 (solute carrier family 8 member A2)	protein interactions	6543	10	1	19454	50	GPM6A
2.541e-02	-3.67	SERPINB11 (serpin family B member 11)	protein interactions	89778	10	1	19454	50	CPE
2.541e-02	-3.67	PGM5 (phosphoglucomutase 5)	protein interactions	5239	10	1	19454	50	DMD
2.541e-02	-3.67	DEFA1B (defensin alpha 1B)	protein interactions	728358	10	1	19454	50	PPP2R2B
2.541e-02	-3.67	CDH4 (cadherin 4)	protein interactions	1002	10	1	19454	50	CTNNA3
2.541e-02	-3.67	P2rx7 (purinergic receptor P2X 7)	protein interactions	29665	10	1	19454	50	PTPRZ1
2.541e-02	-3.67	CALB2 (calbindin 2)	protein interactions	794	10	1	19454	50	GPM6A
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.546e-02	-3.67	TYR_PHOSPHATASE_1	prosite domains	PS00383	72	2	12186	42	PTPRT,PTPRZ1
2.550e-02	-3.67	heparan sulfate biosynthesis	BIOCYC pathways	META_PWY-6564	23	1	902	1	HS6ST3
2.573e-02	-3.66	Post-translational modification: synthesis of GPI-anchored proteins	REACTOME pathways	R-HSA-163125	92	2	10285	28	LSAMP,NTM
2.581e-02	-3.66	PLCB3 (phospholipase C beta 3)	protein interactions	5331	97	2	19454	50	PRKG1,CTNNA3
2.581e-02	-3.66	BTG3 (BTG anti-proliferation factor 3)	protein interactions	10950	97	2	19454	50	CLU,SPARCL1
2.581e-02	-3.66	SNTA1 (syntrophin alpha 1)	protein interactions	6640	97	2	19454	50	DMD,DTNA
2.585e-02	-3.66	NCOR2 (nuclear receptor corepressor 2)	protein interactions	9612	248	3	19454	50	DGKG,TNIK,SOX6
2.595e-02	-3.65	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	48	PCDH9,CTNND2,PTPRT
2.595e-02	-3.65	PTPc_motif	smart domains	SM00404	61	2	9717	40	PTPRT,PTPRZ1
2.595e-02	-3.65	response to organic substance	biological process	GO:0010033	2498	12	18204	48	ATP1A2,ZBTB20,GRIA1,TNIK,GABRB1,SLC1A2,NTRK2,SLC1A3,CLU,AQP4,LIFR,PTPRT
2.606e-02	-3.65	Brain-Derived Neurotrophic Factor (BDNF) signaling pathway	WikiPathways	WP2380	144	3	5310	24	GRIA1,MAPK10,NTRK2
2.606e-02	-3.65	trans-synaptic signaling, modulating synaptic transmission	biological process	GO:0099550	10	1	18204	48	NTRK2
2.606e-02	-3.65	retinal rod cell development	biological process	GO:0046548	10	1	18204	48	NTRK2
2.606e-02	-3.65	response to histamine	biological process	GO:0034776	10	1	18204	48	GABRB1
2.606e-02	-3.65	regulation of mesenchymal stem cell differentiation	biological process	GO:2000739	10	1	18204	48	SOX6
2.606e-02	-3.65	substrate-independent telencephalic tangential migration	biological process	GO:0021826	10	1	18204	48	NRG3
2.606e-02	-3.65	positive regulation of lipopolysaccharide-mediated signaling pathway	biological process	GO:0031666	10	1	18204	48	SASH1
2.606e-02	-3.65	substrate-independent telencephalic tangential interneuron migration	biological process	GO:0021843	10	1	18204	48	NRG3
2.606e-02	-3.65	regulation of postsynaptic cytosolic calcium ion concentration	biological process	GO:0099566	10	1	18204	48	GRIA1
2.616e-02	-3.64	negative regulation of biological process	biological process	GO:0048519	5737	22	18204	48	ATP1A2,QKI,ZBTB20,MYO16,SOX6,PRKG1,GFAP,SPON1,GRIA1,CST3,GRID2,PTPRZ1,DCLK1,NTRK2,GLIS3,CLU,NRG3,GRIA4,DGKG,DMD,GPM6B,PTPRT
2.622e-02	-3.64	nervous system process	biological process	GO:0050877	1376	8	18204	48	GRIA1,PTPRZ1,GRID2,SLC1A3,CSMD1,AQP4,NTRK2,ATP1A2
2.631e-02	-3.64	DMD (dystrophin)	protein interactions	1756	98	2	19454	50	DTNA,DMD
2.647e-02	-3.63	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	5	16828	48	SPON1,SOX6,PDZRN4,CTNND2,CTNNA3
2.666e-02	-3.62	DAGK_acc	pfam domains	PF00609	10	1	17795	48	DGKG
2.666e-02	-3.62	PAS_3	pfam domains	PF08447	10	1	17795	48	NPAS3
2.666e-02	-3.62	Laminin_G_1	pfam domains	PF00054	10	1	17795	48	LAMA2
2.666e-02	-3.62	Ig_sub2	interpro domains	IPR003598	239	3	18521	50	NTM,LSAMP,NTRK2
2.668e-02	-3.62	Diacylglycerol_kin_accessory	interpro domains	IPR000756	10	1	18521	50	DGKG
2.668e-02	-3.62	Doublecortin_dom_sf	interpro domains	IPR036572	10	1	18521	50	DCLK1
2.668e-02	-3.62	DGK	interpro domains	IPR037607	10	1	18521	50	DGKG
2.668e-02	-3.62	MIP_CS	interpro domains	IPR022357	10	1	18521	50	AQP4
2.668e-02	-3.62	PAS_fold_3	interpro domains	IPR013655	10	1	18521	50	NPAS3
2.680e-02	-3.62	DEFA1 (defensin alpha 1)	protein interactions	1667	99	2	19454	50	SMOC1,LIFR
2.680e-02	-3.62	TNKS (tankyrase)	protein interactions	8658	99	2	19454	50	PCDH9,TNIK
2.690e-02	-3.62	Activation of the AP-1 family of transcription factors	REACTOME pathways	R-HSA-450341	10	1	10285	28	MAPK10
2.690e-02	-3.62	PI3K events in ERBB4 signaling	REACTOME pathways	R-HSA-1250342	10	1	10285	28	NRG3
2.701e-02	-3.61	anchoring junction	cellular component	GO:0070161	902	6	19108	49	DMD,CTNNA3,CTNND2,GRIA1,PCDH9,ATP1A2
2.702e-02	-3.61	Bile secretion	KEGG pathways	ko04976	71	2	7161	26	ATP1A2,AQP4
2.702e-02	-3.61	Bile secretion	KEGG pathways	hsa04976	71	2	7161	26	AQP4,ATP1A2
2.725e-02	-3.60	LAMININ_IVA	prosite domains	PS51115	8	1	12186	42	LAMA2
2.730e-02	-3.60	alpha-catenin binding	molecular function	GO:0045294	10	1	18094	50	PTPRT
2.730e-02	-3.60	neurotrophin binding	molecular function	GO:0043121	10	1	18094	50	NTRK2
2.731e-02	-3.60	PLG (plasminogen)	protein interactions	5340	100	2	19454	50	DPP6,PPP2R2B
2.731e-02	-3.60	DTNB (dystrobrevin beta)	protein interactions	1838	100	2	19454	50	DMD,DTNA
2.731e-02	-3.60	ATP4A (ATPase H+/K+ transporting subunit alpha)	protein interactions	495	100	2	19454	50	GPM6A,ATP1A2
2.756e-02	-3.59	cellular response to acid chemical	biological process	GO:0071229	98	2	18204	48	NTRK2,GRIA1
2.769e-02	-3.59	potassium channel complex	cellular component	GO:0034705	101	2	19108	49	DPP6,GRIK1
2.772e-02	-3.59	heparan sulfate biosynthesis	BIOCYC pathways	HUMAN_PWY-6564	25	1	902	1	HS6ST3
2.777e-02	-3.58	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing	91	2	16828	48	GRIA1,SOX6
2.781e-02	-3.58	FAM110A (family with sequence similarity 110 member A)	protein interactions	83541	101	2	19454	50	DCLK1,CTNNA3
2.781e-02	-3.58	PRKCG (protein kinase C gamma)	protein interactions	5582	101	2	19454	50	GFAP,GRIA4
2.786e-02	-3.58	G protein-coupled receptor complex	cellular component	GO:0097648	11	1	19108	49	GABBR2
2.786e-02	-3.58	perisynaptic extracellular matrix	cellular component	GO:0098966	11	1	19108	49	PTPRZ1
2.792e-02	-3.58	C17orf50 (chromosome 17 open reading frame 50)	protein interactions	146853	11	1	19454	50	CTNNA3
2.792e-02	-3.58	SPATS1 (spermatogenesis associated serine rich 1)	protein interactions	221409	11	1	19454	50	CTNNA3
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	PRKG1
2.792e-02	-3.58	CACNG8 (calcium voltage-gated channel auxiliary subunit gamma 8)	protein interactions	59283	11	1	19454	50	GRIA1
2.792e-02	-3.58	MSRB1 (methionine sulfoxide reductase B1)	protein interactions	51734	11	1	19454	50	CLU
2.792e-02	-3.58	NEUROD4 (neuronal differentiation 4)	protein interactions	58158	11	1	19454	50	GABRB1
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	AQP5 (aquaporin 5)	protein interactions	362	11	1	19454	50	ATP1A2
2.792e-02	-3.58	SYN3 (synapsin III)	protein interactions	8224	11	1	19454	50	GPM6A
2.792e-02	-3.58	KCTD16 (potassium channel tetramerization domain containing 16)	protein interactions	57528	11	1	19454	50	GABBR2
2.792e-02	-3.58	NTS (neurotensin)	protein interactions	4922	11	1	19454	50	CPE
2.792e-02	-3.58	ZG16 (zymogen granule protein 16)	protein interactions	653808	11	1	19454	50	CTNNA3
2.808e-02	-3.57	spinal cord development	biological process	GO:0021510	99	2	18204	48	SOX6,GRIA1
2.808e-02	-3.57	heart contraction	biological process	GO:0060047	99	2	18204	48	ATP1A2,DMD
2.814e-02	-3.57	PROKAR_LIPOPROTEIN	prosite domains	PS51257	76	2	12186	42	GLIS3,CPE
2.817e-02	-3.57	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	48	QKI
2.822e-02	-3.57	cellular response to endogenous stimulus	biological process	GO:0071495	1135	7	18204	48	GRIA1,SOX6,GABRB1,SLC1A2,SLC1A3,NTRK2,ATP1A2
2.832e-02	-3.56	HP (haptoglobin)	protein interactions	3240	102	2	19454	50	CLU,PPP2R2B
2.832e-02	-3.56	TMPRSS13 (transmembrane serine protease 13)	protein interactions	84000	102	2	19454	50	SPON1,CPE
2.861e-02	-3.55	regulation of dendrite development	biological process	GO:0050773	100	2	18204	48	TNIK,DGKG
2.863e-02	-3.55	negative regulation of neuron migration	biological process	GO:2001223	11	1	18204	48	NRG3
2.863e-02	-3.55	glutamate secretion	biological process	GO:0014047	11	1	18204	48	NTRK2
2.863e-02	-3.55	ectodermal placode formation	biological process	GO:0060788	11	1	18204	48	NRG3
2.863e-02	-3.55	regulation of peptidyl-cysteine S-nitrosylation	biological process	GO:2000169	11	1	18204	48	DMD
2.863e-02	-3.55	L-ascorbic acid metabolic process	biological process	GO:0019852	11	1	18204	48	ATP1A2
2.863e-02	-3.55	negative regulation of platelet aggregation	biological process	GO:0090331	11	1	18204	48	PRKG1
2.863e-02	-3.55	lipid phosphorylation	biological process	GO:0046834	11	1	18204	48	DGKG
2.863e-02	-3.55	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	48	QKI
2.863e-02	-3.55	negative regulation of cardiac muscle cell differentiation	biological process	GO:2000726	11	1	18204	48	SOX6
2.863e-02	-3.55	physiological muscle hypertrophy	biological process	GO:0003298	11	1	18204	48	PRKG1
2.863e-02	-3.55	establishment or maintenance of transmembrane electrochemical gradient	biological process	GO:0010248	11	1	18204	48	ATP1A2
2.863e-02	-3.55	ectodermal placode morphogenesis	biological process	GO:0071697	11	1	18204	48	NRG3
2.863e-02	-3.55	cell growth involved in cardiac muscle cell development	biological process	GO:0061049	11	1	18204	48	PRKG1
2.863e-02	-3.55	Bergmann glial cell differentiation	biological process	GO:0060020	11	1	18204	48	GFAP
2.863e-02	-3.55	regulation of basement membrane organization	biological process	GO:0110011	11	1	18204	48	LAMA2
2.863e-02	-3.55	lactone metabolic process	biological process	GO:1901334	11	1	18204	48	ATP1A2
2.863e-02	-3.55	regulation of Schwann cell proliferation	biological process	GO:0010624	11	1	18204	48	GFAP
2.863e-02	-3.55	physiological cardiac muscle hypertrophy	biological process	GO:0003301	11	1	18204	48	PRKG1
2.886e-02	-3.55	Doublecortin domain	gene3d domains	3.10.20.230	9	1	14470	47	DCLK1
2.889e-02	-3.54	MARK2 (microtubule affinity regulating kinase 2)	protein interactions	2011	259	3	19454	50	DTNA,PPP2R2B,DMD
2.891e-02	-3.54	aldosterone_producing	COSMIC cancer mutations	aldosterone_producing	93	2	16828	48	SOX6,GRIA1
2.894e-02	-3.54	Ig-like_dom	interpro domains	IPR007110	432	4	18521	50	LSAMP,PTPRT,NTRK2,NTM
2.931e-02	-3.53	Tyr_kinase_rcpt_2_CS	interpro domains	IPR002011	11	1	18521	50	NTRK2
2.936e-02	-3.53	HUNK (hormonally up-regulated Neu-associated kinase)	protein interactions	30811	104	2	19454	50	SPARCL1,CLU
2.958e-02	-3.52	breast-carcinoma	COSMIC cancer mutations	breast-carcinoma	15030	47	16828	48	DCLK1,PRKG1,SOX6,GABRB1,ZBTB20,PCDH9,DGKG,LIFR,NPAS3,GLIS3,CPE,NRG3,GRIK1,TNIK,SLC1A3,PHYHIPL,PDZRN4,SASH1,MYO16,LSAMP,CST3,DMD,GPM6A,GPM6B,GFAP,CTNNA3,QKI,PPP2R2B,CLU,DPP6,SLC1A2,GRID2,PTPRZ1,SPON1,LAMA2,GRIA4,GRIA1,HS6ST3,AQP4,CTNND2,SPARCL1,NTRK2,ATP1A2,SMOC1,GABBR2,PTPRT,NTM
2.969e-02	-3.52	phosphate-containing compound metabolic process	biological process	GO:0006796	1681	9	18204	48	ATP1A2,DCLK1,NTRK2,PTPRZ1,PTPRT,MAPK10,DGKG,PRKG1,TNIK
2.970e-02	-3.52	cellular macromolecule localization	biological process	GO:0070727	1962	10	18204	48	DMD,GPM6B,GFAP,GRID2,TNIK,DPP6,CPE,DCLK1,QKI,CLU
2.979e-02	-3.51	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis	413	4	16828	48	GRIK1,DGKG,PTPRT,MYO16
2.979e-02	-3.51	myelofibrosis	COSMIC cancer mutations	myelofibrosis	413	4	16828	48	PTPRT,MYO16,DGKG,GRIK1
2.999e-02	-3.51	sulfur amino acid transmembrane transporter activity	molecular function	GO:0000099	11	1	18094	50	SLC1A2
2.999e-02	-3.51	nitric-oxide synthase binding	molecular function	GO:0050998	11	1	18094	50	DMD
2.999e-02	-3.51	ATP-dependent diacylglycerol kinase activity	molecular function	GO:0004143	11	1	18094	50	DGKG
2.999e-02	-3.51	structural constituent of myelin sheath	molecular function	GO:0019911	11	1	18094	50	GPM6B
2.999e-02	-3.51	STAT family protein binding	molecular function	GO:0097677	11	1	18094	50	PTPRT
2.999e-02	-3.51	dystroglycan binding	molecular function	GO:0002162	11	1	18094	50	DMD
3.021e-02	-3.50	regulation of heart rate	biological process	GO:0002027	103	2	18204	48	CTNNA3,DMD
3.025e-02	-3.50	protein serine/threonine kinase activity	molecular function	GO:0004674	428	4	18094	50	DCLK1,MAPK10,TNIK,PRKG1
3.027e-02	-3.50	filopodium	cellular component	GO:0030175	106	2	19108	49	GPM6A,DMD
3.033e-02	-3.50	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	8	16828	48	NTM,ATP1A2,NPAS3,GRIA4,ZBTB20,PTPRT,GRID2,PDZRN4
3.035e-02	-3.49	sodium:potassium-exchanging ATPase complex	cellular component	GO:0005890	12	1	19108	49	ATP1A2
3.035e-02	-3.49	synapse-associated extracellular matrix	cellular component	GO:0099535	12	1	19108	49	PTPRZ1
3.042e-02	-3.49	CTF1 (cardiotrophin 1)	protein interactions	1489	12	1	19454	50	LIFR
3.042e-02	-3.49	INTS4P2 (integrator complex subunit 4 pseudogene 2)	protein interactions	644619	12	1	19454	50	GFAP
3.042e-02	-3.49	KIF26A (kinesin family member 26A)	protein interactions	26153	12	1	19454	50	MAPK10
3.042e-02	-3.49	NTF4 (neurotrophin 4)	protein interactions	4909	12	1	19454	50	NTRK2
3.042e-02	-3.49	TREM2 (triggering receptor expressed on myeloid cells 2)	protein interactions	54209	12	1	19454	50	CLU
3.042e-02	-3.49	MMP25 (matrix metallopeptidase 25)	protein interactions	64386	12	1	19454	50	CLU
3.042e-02	-3.49	ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group))	protein interactions	420	12	1	19454	50	GPM6A
3.042e-02	-3.49	MYBPHL (myosin binding protein H like)	protein interactions	343263	12	1	19454	50	GFAP
3.042e-02	-3.49	PROK2 (prokineticin 2)	protein interactions	60675	12	1	19454	50	CPE
3.042e-02	-3.49	LMP-1 (latent membrane protein LMP-1)	protein interactions	3783750	12	1	19454	50	TNIK
3.044e-02	-3.49	Prot-tyrosine_phosphatase-like	interpro domains	IPR029021	101	2	18521	50	PTPRT,PTPRZ1
3.053e-02	-3.49	regulation of phosphate metabolic process	biological process	GO:0019220	1154	7	18204	48	PTPRT,DMD,SASH1,TNIK,PRKG1,ZBTB20,NTRK2
3.060e-02	-3.49	DC	prosite domains	PS50309	9	1	12186	42	DCLK1
3.060e-02	-3.49	CYSTATIN	prosite domains	PS00287	9	1	12186	42	CST3
3.066e-02	-3.48	regulation of phosphorus metabolic process	biological process	GO:0051174	1155	7	18204	48	NTRK2,ZBTB20,SASH1,DMD,PTPRT,TNIK,PRKG1
3.072e-02	-3.48	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	25	16828	48	DMD,CTNNA3,PTPRT,NTM,CLU,PHYHIPL,CTNND2,SASH1,ATP1A2,NTRK2,PTPRZ1,GRID2,LIFR,SPON1,GRIA4,LAMA2,CPE,GRIA1,TNIK,NRG3,PRKG1,DCLK1,GABRB1,ZBTB20,DGKG
3.072e-02	-3.48	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	25	16828	48	PHYHIPL,CTNND2,NTRK2,ATP1A2,SASH1,DMD,PTPRT,CTNNA3,CLU,NTM,DCLK1,PRKG1,GABRB1,ZBTB20,DGKG,GRID2,PTPRZ1,SPON1,LIFR,GRIA4,LAMA2,NRG3,TNIK,GRIA1,CPE
3.091e-02	-3.48	positive regulation of cell differentiation	biological process	GO:0045597	906	6	18204	48	NTRK2,QKI,GFAP,SOX6,LAMA2,PTPRZ1
3.093e-02	-3.48	ERRFI1 (ERBB receptor feedback inhibitor 1)	protein interactions	54206	107	2	19454	50	GFAP,PHYHIPL
3.119e-02	-3.47	protein tyrosine phosphatase activity	molecular function	GO:0004725	100	2	18094	50	PTPRZ1,PTPRT
3.120e-02	-3.47	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	biological process	GO:0015015	12	1	18204	48	HS6ST3
3.120e-02	-3.47	microglia differentiation	biological process	GO:0014004	12	1	18204	48	QKI
3.120e-02	-3.47	regulation of blood vessel remodeling	biological process	GO:0060312	12	1	18204	48	CST3
3.120e-02	-3.47	negative regulation of smooth muscle contraction	biological process	GO:0045986	12	1	18204	48	PRKG1
3.120e-02	-3.47	negative regulation of protein localization to cell surface	biological process	GO:2000009	12	1	18204	48	GPM6B
3.120e-02	-3.47	sulfur amino acid transport	biological process	GO:0000101	12	1	18204	48	SLC1A2
3.120e-02	-3.47	regulation of ventricular cardiac muscle cell action potential	biological process	GO:0098911	12	1	18204	48	CTNNA3
3.120e-02	-3.47	auditory behavior	biological process	GO:0031223	12	1	18204	48	SLC1A3
3.120e-02	-3.47	positive regulation of membrane potential	biological process	GO:0045838	12	1	18204	48	GRIA1
3.120e-02	-3.47	positive regulation of integrin-mediated signaling pathway	biological process	GO:2001046	12	1	18204	48	LAMA2
3.120e-02	-3.47	negative regulation of collagen metabolic process	biological process	GO:0010713	12	1	18204	48	CST3
3.129e-02	-3.46	gland morphogenesis	biological process	GO:0022612	105	2	18204	48	NRG3,CSMD1
3.139e-02	-3.46	regulation of blood circulation	biological process	GO:1903522	261	3	18204	48	CTNNA3,DMD,ATP1A2
3.147e-02	-3.46	HSP90AA4P (heat shock protein 90 alpha family class A member 4, pseudogene)	protein interactions	3323	108	2	19454	50	SMOC1,DTNA
3.147e-02	-3.46	BIN1 (bridging integrator 1)	protein interactions	274	108	2	19454	50	GPM6A,CLU
3.190e-02	-3.45	CarboxypepD_reg	pfam domains	PF13620	12	1	17795	48	CPE
3.190e-02	-3.45	Sulfotransfer_2	pfam domains	PF03567	12	1	17795	48	HS6ST3
3.193e-02	-3.44	MAP_kinase_CS	interpro domains	IPR003527	12	1	18521	50	MAPK10
3.193e-02	-3.44	Sulfotransferase	interpro domains	IPR005331	12	1	18521	50	HS6ST3
3.200e-02	-3.44	SIPA1L3 (signal induced proliferation associated 1 like 3)	protein interactions	23094	109	2	19454	50	GFAP,GRIK1
3.204e-02	-3.44	human chr9q21.33	chromosome location	human chr9q21.33	17	1	26134	50	NTRK2
3.204e-02	-3.44	human chr5q33.2	chromosome location	human chr5q33.2	17	1	26134	50	GRIA1
3.207e-02	-3.44	chemical homeostasis	biological process	GO:0048878	914	6	18204	48	SLC1A3,CSMD1,AQP4,ZBTB20,ATP1A2,GRIA1
3.220e-02	-3.44	Ionotropic activity of Kainate Receptors	REACTOME pathways	R-HSA-451306	12	1	10285	28	GRIK1
3.220e-02	-3.44	Activation of Ca-permeable Kainate Receptor	REACTOME pathways	R-HSA-451308	12	1	10285	28	GRIK1
3.222e-02	-3.44	cGMP signaling	KEGG pathways	M00694	9	1	7161	26	PRKG1
3.222e-02	-3.44	cGMP signaling	KEGG pathways	hsa_M00694	9	1	7161	26	PRKG1
3.223e-02	-3.43	positive regulation of cell development	biological process	GO:0010720	458	4	18204	48	QKI,NTRK2,PTPRZ1,GFAP
3.237e-02	-3.43	phosphorus metabolic process	biological process	GO:0006793	1707	9	18204	48	DCLK1,NTRK2,ATP1A2,TNIK,PRKG1,DGKG,MAPK10,PTPRT,PTPRZ1
3.243e-02	-3.43	large_intestine-rectum-adenoma	COSMIC cancer mutations	large_intestine-rectum-adenoma	99	2	16828	48	NTRK2,LIFR
3.247e-02	-3.43	LamB	smart domains	SM00281	8	1	9717	40	LAMA2
3.267e-02	-3.42	gamma-catenin binding	molecular function	GO:0045295	12	1	18094	50	PTPRT
3.267e-02	-3.42	G protein-coupled neurotransmitter receptor activity	molecular function	GO:0099528	12	1	18094	50	GABRB1
3.267e-02	-3.42	vinculin binding	molecular function	GO:0017166	12	1	18094	50	DMD
3.267e-02	-3.42	adenylate cyclase binding	molecular function	GO:0008179	12	1	18094	50	GRIA1
3.267e-02	-3.42	dipeptidyl-peptidase activity	molecular function	GO:0008239	12	1	18094	50	DPP6
3.281e-02	-3.42	distal axon	cellular component	GO:0150034	273	3	19108	49	NTRK2,GPM6A,PCDH9
3.284e-02	-3.42	cytoplasmic side of lysosomal membrane	cellular component	GO:0098574	13	1	19108	49	GFAP
3.291e-02	-3.41	TBCC (tubulin folding cofactor C)	protein interactions	6903	13	1	19454	50	NTM
3.291e-02	-3.41	RAB3C (RAB3C, member RAS oncogene family)	protein interactions	115827	13	1	19454	50	GPM6A
3.291e-02	-3.41	KCNQ2 (potassium voltage-gated channel subfamily Q member 2)	protein interactions	3785	13	1	19454	50	GRIK1
3.291e-02	-3.41	EID2B (EP300 interacting inhibitor of differentiation 2B)	protein interactions	126272	13	1	19454	50	CTNNA3
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.312e-02	-3.41	cell migration	biological process	GO:0016477	921	6	18204	48	PRKG1,GPM6A,CTNNA3,NTRK2,DCLK1,NRG3
3.312e-02	-3.41	Protein tyrosine phosphatase superfamily	gene3d domains	3.90.190.10	88	2	14470	47	PTPRZ1,PTPRT
3.319e-02	-3.41	arm	COSMIC cancer mutations	arm	1331	8	16828	48	GRID2,NPAS3,ZBTB20,GRIA4,PDZRN4,PTPRT,NTM,ATP1A2
3.322e-02	-3.40	protein domain specific binding	molecular function	GO:0019904	651	5	18094	50	QKI,GRID2,DTNA,GRIA1,SPON1
3.333e-02	-3.40	cellular response to organic substance	biological process	GO:0071310	1716	9	18204	48	ATP1A2,SLC1A3,AQP4,ZBTB20,GABRB1,SLC1A2,LIFR,GRIA1,PTPRT
3.349e-02	-3.40	endometrium-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-endometrioid_carcinoma	15680	48	16828	48	ZBTB20,PCDH9,DGKG,DCLK1,PRKG1,SOX6,GABRB1,DTNA,GLIS3,CPE,NRG3,TNIK,GRIK1,LIFR,NPAS3,PDZRN4,SASH1,SLC1A3,PHYHIPL,GPM6A,GPM6B,GFAP,QKI,PPP2R2B,CTNNA3,CLU,DPP6,MYO16,CST3,LSAMP,DMD,SLC1A2,LAMA2,GRIA4,GRIA1,GRID2,PTPRZ1,SPON1,AQP4,CTNND2,SPARCL1,NTRK2,ATP1A2,HS6ST3,PTPRT,NTM,SMOC1,GABBR2
3.351e-02	-3.40	positive regulation of tumor necrosis factor production	biological process	GO:0032760	109	2	18204	48	ZBTB20,CLU
3.352e-02	-3.40	exopeptidase activity	molecular function	GO:0008238	104	2	18094	50	CPE,DPP6
3.363e-02	-3.39	HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1)	protein interactions	3157	112	2	19454	50	GPM6A,PPP2R2B
3.371e-02	-3.39	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	48	QKI
3.375e-02	-3.39	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	48	ATP1A2
3.375e-02	-3.39	negative regulation of amyloid fibril formation	biological process	GO:1905907	13	1	18204	48	CLU
3.375e-02	-3.39	regulation of postsynaptic density assembly	biological process	GO:0099151	13	1	18204	48	GRID2
3.375e-02	-3.39	ectodermal placode development	biological process	GO:0071696	13	1	18204	48	NRG3
3.375e-02	-3.39	regulation of respiratory gaseous exchange by nervous system process	biological process	GO:0002087	13	1	18204	48	ATP1A2
3.375e-02	-3.39	prepulse inhibition	biological process	GO:0060134	13	1	18204	48	GRID2
3.375e-02	-3.39	negative regulation of homotypic cell-cell adhesion	biological process	GO:0034111	13	1	18204	48	PRKG1
3.375e-02	-3.39	cerebellar granular layer development	biological process	GO:0021681	13	1	18204	48	GRID2
3.383e-02	-3.39	kidney-carcinoma-chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-chromophobe_renal_cell_carcinoma	430	4	16828	48	PRKG1,DCLK1,TNIK,NTRK2
3.383e-02	-3.39	chromophobe_renal_cell_carcinoma	COSMIC cancer mutations	chromophobe_renal_cell_carcinoma	430	4	16828	48	PRKG1,DCLK1,TNIK,NTRK2
3.383e-02	-3.39	TYR_PHOSPHATASE_2	prosite domains	PS50056	84	2	12186	42	PTPRT,PTPRZ1
3.386e-02	-3.39	Transmembrane transport of small molecules	REACTOME pathways	R-HSA-382551	677	5	10285	28	ATP1A2,SLC1A2,SLC1A3,AQP4,GABRB1
3.388e-02	-3.38	PICK1 (protein interacting with PRKCA 1)	protein interactions	9463	477	4	19454	50	DMD,GRIK1,GRIA4,GRIA1
3.389e-02	-3.38	human chr4p12	chromosome location	human chr4p12	18	1	26134	50	GABRB1
3.389e-02	-3.38	human chr7q31.32	chromosome location	human chr7q31.32	18	1	26134	50	PTPRZ1
3.395e-02	-3.38	MIP	prosite domains	PS00221	10	1	12186	42	AQP4
3.395e-02	-3.38	MAM_1	prosite domains	PS00740	10	1	12186	42	PTPRT
3.397e-02	-3.38	import into cell	biological process	GO:0098657	687	5	18204	48	GFAP,SLC1A2,GRIA1,ATP1A2,SLC1A3
3.400e-02	-3.38	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	28	SLC1A2,SLC1A3
3.408e-02	-3.38	chloride transmembrane transport	biological process	GO:1902476	110	2	18204	48	GABRB1,SLC1A3
3.408e-02	-3.38	positive regulation of cell junction assembly	biological process	GO:1901890	110	2	18204	48	NTRK2,GRID2
3.418e-02	-3.38	UBR2 (ubiquitin protein ligase E3 component n-recognin 2)	protein interactions	23304	113	2	19454	50	GFAP,SMOC1
3.420e-02	-3.38	rhythmic process	biological process	GO:0048511	270	3	18204	48	GABRB1,MAPK10,NTRK2
3.453e-02	-3.37	endometrioid_carcinoma	COSMIC cancer mutations	endometrioid_carcinoma	15690	48	16828	48	NTM,PTPRT,GABBR2,SMOC1,ATP1A2,NTRK2,SPARCL1,CTNND2,AQP4,HS6ST3,GRIA1,GRIA4,LAMA2,SPON1,PTPRZ1,GRID2,SLC1A2,CLU,DPP6,QKI,PPP2R2B,CTNNA3,GFAP,GPM6B,GPM6A,DMD,LSAMP,CST3,MYO16,SASH1,PDZRN4,PHYHIPL,SLC1A3,GRIK1,TNIK,NRG3,CPE,GLIS3,NPAS3,LIFR,DGKG,PCDH9,ZBTB20,DTNA,GABRB1,SOX6,PRKG1,DCLK1
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	PCDH9,ZBTB20
3.474e-02	-3.36	endometrium	COSMIC cancer mutations	endometrium	15692	48	16828	48	NTM,PTPRT,GABBR2,SMOC1,SPARCL1,ATP1A2,NTRK2,AQP4,CTNND2,HS6ST3,GRIA1,LAMA2,GRIA4,SPON1,PTPRZ1,GRID2,SLC1A2,CLU,DPP6,GPM6B,GPM6A,QKI,CTNNA3,PPP2R2B,GFAP,DMD,MYO16,CST3,LSAMP,SASH1,PDZRN4,PHYHIPL,SLC1A3,CPE,GLIS3,GRIK1,TNIK,NRG3,LIFR,NPAS3,PCDH9,DGKG,ZBTB20,DTNA,SOX6,GABRB1,PRKG1,DCLK1
3.484e-02	-3.36	ERBB2 Activates PTK6 Signaling	REACTOME pathways	R-HSA-8847993	13	1	10285	28	NRG3
3.484e-02	-3.36	GABA A receptor activation	REACTOME pathways	R-HSA-977441	13	1	10285	28	GABRB1
3.484e-02	-3.36	Passive transport by Aquaporins	REACTOME pathways	R-HSA-432047	13	1	10285	28	AQP4
3.514e-02	-3.35	biliary_tract-bile_duct-carcinoma-adenocarcinoma	COSMIC cancer mutations	biliary_tract-bile_duct-carcinoma-adenocarcinoma	15095	47	16828	48	NPAS3,LIFR,NRG3,GRIK1,TNIK,GLIS3,CPE,DCLK1,PRKG1,GABRB1,SOX6,DTNA,ZBTB20,DGKG,PCDH9,LSAMP,CST3,MYO16,DMD,GFAP,QKI,PPP2R2B,CTNNA3,GPM6A,GPM6B,DPP6,CLU,SLC1A3,PHYHIPL,PDZRN4,SASH1,GRID2,PTPRZ1,LAMA2,GRIA4,GRIA1,SLC1A2,SMOC1,GABBR2,PTPRT,NTM,HS6ST3,CTNND2,AQP4,NTRK2,ATP1A2,SPARCL1
3.514e-02	-3.35	bile_duct	COSMIC cancer mutations	bile_duct	15095	47	16828	48	SLC1A3,PHYHIPL,SASH1,PDZRN4,DMD,LSAMP,CST3,MYO16,DPP6,CLU,GFAP,QKI,PPP2R2B,CTNNA3,GPM6A,GPM6B,GABRB1,SOX6,DTNA,DCLK1,PRKG1,DGKG,PCDH9,ZBTB20,NPAS3,LIFR,NRG3,GRIK1,TNIK,GLIS3,CPE,HS6ST3,NTRK2,ATP1A2,SPARCL1,CTNND2,AQP4,GABBR2,SMOC1,NTM,PTPRT,SLC1A2,GRID2,PTPRZ1,GRIA1,GRIA4,LAMA2
3.517e-02	-3.35	homeostatic process	biological process	GO:0042592	1456	8	18204	48	ATP1A2,ZBTB20,AQP4,CSMD1,SLC1A3,LAMA2,DMD,GRIA1
3.517e-02	-3.35	Carboxypeptidase-like, regulatory domain	gene3d domains	2.60.40.1120	11	1	14470	47	CPE
3.527e-02	-3.34	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	WikiPathways	WP706	162	3	5310	24	NTRK2,AQP4,SLC1A3
3.528e-02	-3.34	alveolar	COSMIC cancer mutations	alveolar	2414	12	16828	48	GRIA1,CLU,PPP2R2B,LAMA2,GABBR2,SPON1,NPAS3,GRID2,SASH1,SPARCL1,SLC1A3,DCLK1
3.528e-02	-3.34	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar	2414	12	16828	48	GRID2,SPON1,GABBR2,NPAS3,LAMA2,PPP2R2B,GRIA1,CLU,DCLK1,SLC1A3,SASH1,SPARCL1
3.530e-02	-3.34	DTNA (dystrobrevin alpha)	protein interactions	1837	115	2	19454	50	DMD,NTRK2
3.530e-02	-3.34	CDH2 (cadherin 2)	protein interactions	1000	115	2	19454	50	CTNND2,CTNNA3
3.532e-02	-3.34	chromaffin granule	cellular component	GO:0042583	14	1	19108	49	CLU
3.535e-02	-3.34	GABA-gated chloride ion channel activity	molecular function	GO:0022851	13	1	18094	50	GABRB1
3.535e-02	-3.34	potassium ion binding	molecular function	GO:0030955	13	1	18094	50	ATP1A2
3.540e-02	-3.34	GRID2 (glutamate ionotropic receptor delta type subunit 2)	protein interactions	2895	14	1	19454	50	GRIA1
3.540e-02	-3.34	C9 (complement C9)	protein interactions	735	14	1	19454	50	CLU
3.540e-02	-3.34	CTSO (cathepsin O)	protein interactions	1519	14	1	19454	50	CST3
3.540e-02	-3.34	Stag2 (STAG2 cohesin complex component)	protein interactions	20843	14	1	19454	50	CLU
3.540e-02	-3.34	JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)	protein interactions	8681	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	SLC1A2 (solute carrier family 1 member 2)	protein interactions	6506	14	1	19454	50	SLC1A2
3.540e-02	-3.34	FCGBP (Fc gamma binding protein)	protein interactions	8857	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	SH3YL1 (SH3 and SYLF domain containing 1)	protein interactions	26751	14	1	19454	50	GFAP
3.540e-02	-3.34	GAGE1 (G antigen 1)	protein interactions	2543	14	1	19454	50	PRKG1
3.540e-02	-3.34	SPRR2D (small proline rich protein 2D)	protein interactions	6703	14	1	19454	50	PPP2R2B
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1)	protein interactions	26926	14	1	19454	50	CLU
3.540e-02	-3.34	CABS1 (calcium binding protein, spermatid associated 1)	protein interactions	85438	14	1	19454	50	GFAP
3.540e-02	-3.34	Nedd4 (neural precursor cell expressed, developmentally down-regulated 4)	protein interactions	17999	14	1	19454	50	GLIS3
3.549e-02	-3.34	extracellular matrix organization	biological process	GO:0030198	274	3	18204	48	SMOC1,GFAP,GPM6B
3.574e-02	-3.33	human chr11q25	chromosome location	human chr11q25	19	1	26134	50	NTM
3.574e-02	-3.33	human chr5p15.2	chromosome location	human chr5p15.2	19	1	26134	50	CTNND2
3.579e-02	-3.33	heart process	biological process	GO:0003015	113	2	18204	48	DMD,ATP1A2
3.579e-02	-3.33	positive regulation of tumor necrosis factor superfamily cytokine production	biological process	GO:1903557	113	2	18204	48	CLU,ZBTB20
3.579e-02	-3.33	developmental cell growth	biological process	GO:0048588	113	2	18204	48	PRKG1,DCLK1
3.582e-02	-3.33	extracellular structure organization	biological process	GO:0043062	275	3	18204	48	SMOC1,GPM6B,GFAP
3.586e-02	-3.33	SKIL (SKI like proto-oncogene)	protein interactions	6498	116	2	19454	50	SASH1,SPARCL1
3.592e-02	-3.33	PRKACA (protein kinase cAMP-activated catalytic subunit alpha)	protein interactions	5566	486	4	19454	50	TNIK,GFAP,GRIA1,GRIA4
3.604e-02	-3.32	Hypertrophic cardiomyopathy (HCM)	KEGG pathways	ko05410	83	2	7161	26	DMD,LAMA2
3.604e-02	-3.32	Hypertrophic cardiomyopathy (HCM)	KEGG pathways	hsa05410	83	2	7161	26	LAMA2,DMD
3.609e-02	-3.32	stomach-carcinoma	COSMIC cancer mutations	stomach-carcinoma	439	4	16828	48	DCLK1,PRKG1,NTRK2,TNIK
3.615e-02	-3.32	external encapsulating structure organization	biological process	GO:0045229	276	3	18204	48	SMOC1,GFAP,GPM6B
3.630e-02	-3.32	mechanosensory behavior	biological process	GO:0007638	14	1	18204	48	SLC1A3
3.630e-02	-3.32	negative regulation of sodium ion transmembrane transporter activity	biological process	GO:2000650	14	1	18204	48	ATP1A2
3.630e-02	-3.32	regulation of protein K63-linked ubiquitination	biological process	GO:1900044	14	1	18204	48	SASH1
3.630e-02	-3.32	positive regulation of sodium ion transmembrane transporter activity	biological process	GO:2000651	14	1	18204	48	DMD
3.630e-02	-3.32	negative regulation of adenylate cyclase activity	biological process	GO:0007194	14	1	18204	48	GABBR2
3.630e-02	-3.32	sodium ion export across plasma membrane	biological process	GO:0036376	14	1	18204	48	ATP1A2
3.630e-02	-3.32	glutathione biosynthetic process	biological process	GO:0006750	14	1	18204	48	SLC1A2
3.630e-02	-3.32	regulation of long-term synaptic depression	biological process	GO:1900452	14	1	18204	48	GRID2
3.630e-02	-3.32	negative regulation of cardiocyte differentiation	biological process	GO:1905208	14	1	18204	48	SOX6
3.630e-02	-3.32	bundle of His cell to Purkinje myocyte communication	biological process	GO:0086069	14	1	18204	48	CTNNA3
3.630e-02	-3.32	cerebrospinal fluid circulation	biological process	GO:0090660	14	1	18204	48	AQP4
3.630e-02	-3.32	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	48	ATP1A2
3.637e-02	-3.31	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	48	PRKG1,MAPK10
3.642e-02	-3.31	ZMYND19 (zinc finger MYND-type containing 19)	protein interactions	116225	117	2	19454	50	CTNND2,SPON1
3.646e-02	-3.31	DCX	smart domains	SM00537	9	1	9717	40	DCLK1
3.646e-02	-3.31	FOLN	smart domains	SM00274	9	1	9717	40	SPARCL1
3.647e-02	-3.31	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	48	QKI
3.656e-02	-3.31	testis-germ_cell_tumour-seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-seminoma	648	5	16828	48	DCLK1,PRKG1,LAMA2,NTRK2,TNIK
3.695e-02	-3.30	cell growth	biological process	GO:0016049	115	2	18204	48	PRKG1,DCLK1
3.699e-02	-3.30	CEACAM8 (CEA cell adhesion molecule 8)	protein interactions	1088	118	2	19454	50	CLU,CPE
3.712e-02	-3.29	MIP	pfam domains	PF00230	14	1	17795	48	AQP4
3.713e-02	-3.29	structural constituent of cytoskeleton	molecular function	GO:0005200	110	2	18094	50	DMD,GFAP
3.715e-02	-3.29	GPCR_3	interpro domains	IPR000337	14	1	18521	50	GABBR2
3.715e-02	-3.29	GPCR_3_CS	interpro domains	IPR017979	14	1	18521	50	GABBR2
3.715e-02	-3.29	Aquaporin-like	interpro domains	IPR023271	14	1	18521	50	AQP4
3.715e-02	-3.29	MIP	interpro domains	IPR000425	14	1	18521	50	AQP4
3.726e-02	-3.29	transferase activity, transferring phosphorus-containing groups	molecular function	GO:0016772	903	6	18094	50	TNIK,DCLK1,NTRK2,MAPK10,PRKG1,DGKG
3.728e-02	-3.29	RECEPTOR_TYR_KIN_II	prosite domains	PS00239	11	1	12186	42	NTRK2
3.728e-02	-3.29	G_PROTEIN_RECEP_F3_3	prosite domains	PS00981	11	1	12186	42	GABBR2
3.747e-02	-3.28	SHC1 events in ERBB4 signaling	REACTOME pathways	R-HSA-1250347	14	1	10285	28	NRG3
3.756e-02	-3.28	RBM7 (RNA binding motif protein 7)	protein interactions	10179	119	2	19454	50	PPP2R2B,QKI
3.756e-02	-3.28	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	2	19454	50	CLU,PCDH9
3.759e-02	-3.28	human chr10q21.1	chromosome location	human chr10q21.1	20	1	26134	50	PHYHIPL
3.759e-02	-3.28	human chr8p21.1	chromosome location	human chr8p21.1	20	1	26134	50	CLU
3.764e-02	-3.28	Sufentanil Action Pathway	SMPDB pathways	SMP0000417	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Remifentanil Action Pathway	SMPDB pathways	SMP0000416	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Escitalopram Action Pathway	SMPDB pathways	SMP0000425	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Levobupivacaine Action Pathway	SMPDB pathways	SMP0000397	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Levorphanol Action Pathway	SMPDB pathways	SMP0000673	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Hydrocodone Action Pathway	SMPDB pathways	SMP0000411	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Oxycodone Action Pathway	SMPDB pathways	SMP0000409	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Anileridine Action Pathway	SMPDB pathways	SMP0000674	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Dibucaine Action Pathway	SMPDB pathways	SMP0000396	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Pentazocine Action Pathway	SMPDB pathways	SMP0000686	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Naltrexone Action Pathway	SMPDB pathways	SMP0000687	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Ropivacaine Action Pathway	SMPDB pathways	SMP0000404	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Proparacaine Action Pathway	SMPDB pathways	SMP0000403	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Ethylmorphine Action Pathway	SMPDB pathways	SMP0000681	26	1	1369	2	ATP1A2
3.764e-02	-3.28	3-Methylthiofentanyl Action Pathway	SMPDB pathways	SMP0000679	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Propoxyphene Action Pathway	SMPDB pathways	SMP0000672	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Naloxone Action Pathway	SMPDB pathways	SMP0000688	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Dimethylthiambutene Action Pathway	SMPDB pathways	SMP0000680	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Alvimopan Action Pathway	SMPDB pathways	SMP0000685	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Cocaine Action Pathway	SMPDB pathways	SMP0000395	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Procaine Action Pathway	SMPDB pathways	SMP0000402	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Fentanyl Action Pathway	SMPDB pathways	SMP0000415	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Hydromorphone Action Pathway	SMPDB pathways	SMP0000410	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Levomethadyl Acetate Action Action Pathway	SMPDB pathways	SMP0000677	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Bupivacaine Action Pathway	SMPDB pathways	SMP0000393	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Chloroprocaine Action Pathway	SMPDB pathways	SMP0000394	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Dezocine Action Pathway	SMPDB pathways	SMP0000676	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Ketobemidone Action Pathway	SMPDB pathways	SMP0000690	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Dihydromorphine Action Pathway	SMPDB pathways	SMP0000689	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Alfentanil Action Pathway	SMPDB pathways	SMP0000413	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Tramadol Action Action Pathway	SMPDB pathways	SMP0000671	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Carfentanil Action Pathway	SMPDB pathways	SMP0000414	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Mepivacaine Action Pathway	SMPDB pathways	SMP0000399	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Buprenorphine Action Pathway	SMPDB pathways	SMP0000684	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Prilocaine Action Pathway	SMPDB pathways	SMP0000401	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Levallorphan Action Pathway	SMPDB pathways	SMP0000683	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Oxymorphone Action Pathway	SMPDB pathways	SMP0000412	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Oxybuprocaine Action Pathway	SMPDB pathways	SMP0000400	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Benzocaine Action Pathway	SMPDB pathways	SMP0000392	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Methadyl Acetate Action Pathway	SMPDB pathways	SMP0000678	26	1	1369	2	ATP1A2
3.764e-02	-3.28	Diphenoxylate Action Pathway	SMPDB pathways	SMP0000675	26	1	1369	2	ATP1A2
3.764e-02	-3.28	ErbB signaling pathway	KEGG pathways	ko04012	85	2	7161	26	MAPK10,NRG3
3.764e-02	-3.28	ErbB signaling pathway	KEGG pathways	hsa04012	85	2	7161	26	NRG3,MAPK10
3.779e-02	-3.28	NEDD4 (NEDD4 E3 ubiquitin protein ligase)	protein interactions	4734	494	4	19454	50	GLIS3,GRIA1,DMD,TNIK
3.780e-02	-3.28	axolemma	cellular component	GO:0030673	15	1	19108	49	SLC1A2
3.780e-02	-3.28	dendritic spine membrane	cellular component	GO:0032591	15	1	19108	49	GRIA1
3.788e-02	-3.27	NPR1 (natriuretic peptide receptor 1)	protein interactions	4881	15	1	19454	50	PRKG1
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	TNIK
3.788e-02	-3.27	FERD3L (Fer3 like bHLH transcription factor)	protein interactions	222894	15	1	19454	50	CTNNA3
3.813e-02	-3.27	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	48	GRID2,NTRK2
3.814e-02	-3.27	ZDHHC15 (zinc finger DHHC-type palmitoyltransferase 15)	protein interactions	158866	120	2	19454	50	DMD,LAMA2
3.830e-02	-3.26	Alpha-catenin/vinculin-like	gene3d domains	1.20.120.230	12	1	14470	47	CTNNA3
3.849e-02	-3.26	Wnt signaling pathway	biological process	GO:0016055	283	3	18204	48	TNIK,CTNND2,CPE
3.854e-02	-3.26	regulation of transmembrane transport	biological process	GO:0034762	485	4	18204	48	ATP1A2,DPP6,DMD,SLC1A2
3.884e-02	-3.25	lung-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-carcinoma-adenocarcinoma	15133	47	16828	48	SPARCL1,NTRK2,ATP1A2,AQP4,CTNND2,HS6ST3,NTM,PTPRT,GABBR2,SMOC1,SLC1A2,GRIA1,LAMA2,GRIA4,SPON1,GRID2,PTPRZ1,SASH1,PDZRN4,SLC1A3,PHYHIPL,DPP6,CLU,GPM6A,GPM6B,GFAP,PPP2R2B,CTNNA3,QKI,DMD,MYO16,LSAMP,PCDH9,DGKG,ZBTB20,SOX6,GABRB1,DTNA,DCLK1,PRKG1,GLIS3,CPE,NRG3,GRIK1,TNIK,LIFR,NPAS3
3.884e-02	-3.25	peripheral nervous system neuron differentiation	biological process	GO:0048934	15	1	18204	48	NTRK2
3.884e-02	-3.25	negative regulation of cyclase activity	biological process	GO:0031280	15	1	18204	48	GABBR2
3.884e-02	-3.25	intracellular potassium ion homeostasis	biological process	GO:0030007	15	1	18204	48	ATP1A2
3.884e-02	-3.25	negative regulation of sodium ion transmembrane transport	biological process	GO:1902306	15	1	18204	48	ATP1A2
3.884e-02	-3.25	peripheral nervous system neuron development	biological process	GO:0048935	15	1	18204	48	NTRK2
3.884e-02	-3.25	collateral sprouting	biological process	GO:0048668	15	1	18204	48	PRKG1
3.884e-02	-3.25	negative regulation of amino acid transport	biological process	GO:0051956	15	1	18204	48	PRKG1
3.884e-02	-3.25	protein homotrimerization	biological process	GO:0070207	15	1	18204	48	SLC1A2
3.884e-02	-3.25	regulation of inositol phosphate biosynthetic process	biological process	GO:0010919	15	1	18204	48	PRKG1
3.894e-02	-3.25	NAKATPASE	prints domains	PR00121	9	1	5227	23	ATP1A2
3.907e-02	-3.24	Nalbuphine Action Pathway	SMPDB pathways	SMP0000691	27	1	1369	2	ATP1A2
3.907e-02	-3.24	Desipramine Action Pathway	SMPDB pathways	SMP0000423	27	1	1369	2	ATP1A2
3.923e-02	-3.24	DNA-binding transcription repressor activity	molecular function	GO:0001217	272	3	18094	50	SOX6,ZBTB20,GLIS3
3.923e-02	-3.24	phosphatase activity	molecular function	GO:0016791	272	3	18094	50	ATP1A2,PTPRT,PTPRZ1
3.925e-02	-3.24	prostate-adenoma	COSMIC cancer mutations	prostate-adenoma	1634	9	16828	48	SASH1,GRIK1,ZBTB20,GABBR2,NPAS3,PRKG1,MYO16,PTPRZ1,GRID2
3.930e-02	-3.24	MED31 (mediator complex subunit 31)	protein interactions	51003	122	2	19454	50	CPE,QKI
3.943e-02	-3.23	human chr4q32.3	chromosome location	human chr4q32.3	21	1	26134	50	CPE
3.943e-02	-3.23	human chr13q32.1	chromosome location	human chr13q32.1	21	1	26134	50	HS6ST3
3.943e-02	-3.23	human chr10q23.1	chromosome location	human chr10q23.1	21	1	26134	50	NRG3
3.972e-02	-3.23	Cation_ATPase_C	pfam domains	PF00689	15	1	17795	48	ATP1A2
3.972e-02	-3.23	CNH	pfam domains	PF00780	15	1	17795	48	TNIK
3.972e-02	-3.23	DAGK_cat	pfam domains	PF00781	15	1	17795	48	DGKG
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	TNIK
3.975e-02	-3.23	Diacylglycerol_kinase_cat_dom	interpro domains	IPR001206	15	1	18521	50	DGKG
3.975e-02	-3.23	ATPase_P-typ_cation-transptr_C	interpro domains	IPR006068	15	1	18521	50	ATP1A2
3.992e-02	-3.22	regulation of peptidyl-serine phosphorylation	biological process	GO:0033135	120	2	18204	48	DMD,NTRK2
3.995e-02	-3.22	active monoatomic ion transmembrane transporter activity	molecular function	GO:0022853	274	3	18094	50	ATP1A2,SLC1A2,SLC1A3
4.008e-02	-3.22	PROTEIN_KINASE_ATP	prosite domains	PS00107	377	4	12186	42	TNIK,DCLK1,PRKG1,NTRK2
4.009e-02	-3.22	ERBB2 Regulates Cell Motility	REACTOME pathways	R-HSA-6785631	15	1	10285	28	NRG3
4.009e-02	-3.22	GABAergic synapse	KEGG pathways	ko04727	88	2	7161	26	GABRB1,GABBR2
4.009e-02	-3.22	GABAergic synapse	KEGG pathways	hsa04727	88	2	7161	26	GABBR2,GABRB1
4.022e-02	-3.21	ErbB receptor signaling network	Pathway Interaction DB	erbb_network_pathway	13	1	2226	7	NRG3
4.035e-02	-3.21	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	1	19454	50	ZBTB20
4.035e-02	-3.21	KCNJ4 (potassium inwardly rectifying channel subfamily J member 4)	protein interactions	3761	16	1	19454	50	DMD
4.035e-02	-3.21	ORM2 (orosomucoid 2)	protein interactions	5005	16	1	19454	50	PPP2R2B
4.035e-02	-3.21	IFFO2 (intermediate filament family orphan 2)	protein interactions	126917	16	1	19454	50	GFAP
4.035e-02	-3.21	RETNLB (resistin like beta)	protein interactions	84666	16	1	19454	50	SMOC1
4.035e-02	-3.21	CNTNAP2 (contactin associated protein 2)	protein interactions	26047	16	1	19454	50	CPE
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	CTNNA3
4.035e-02	-3.21	CNTFR (ciliary neurotrophic factor receptor)	protein interactions	1271	16	1	19454	50	LIFR
4.035e-02	-3.21	TAMALIN (trafficking regulator and scaffold protein tamalin)	protein interactions	160622	16	1	19454	50	GABBR2
4.035e-02	-3.21	FNDC8 (fibronectin type III domain containing 8)	protein interactions	54752	16	1	19454	50	SPARCL1
4.035e-02	-3.21	TMCO6 (transmembrane and coiled-coil domains 6)	protein interactions	55374	16	1	19454	50	PHYHIPL
4.035e-02	-3.21	GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)	protein interactions	114805	16	1	19454	50	TNIK
4.035e-02	-3.21	GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1)	protein interactions	2569	16	1	19454	50	PRKG1
4.036e-02	-3.21	skin-malignant_melanoma	COSMIC cancer mutations	skin-malignant_melanoma	15741	48	16828	48	SLC1A3,PHYHIPL,SASH1,PDZRN4,DMD,CST3,LSAMP,MYO16,CLU,DPP6,GFAP,QKI,PPP2R2B,CTNNA3,GPM6A,GPM6B,SOX6,GABRB1,DTNA,DCLK1,PRKG1,DGKG,PCDH9,ZBTB20,NPAS3,LIFR,NRG3,TNIK,GRIK1,GLIS3,CPE,HS6ST3,NTRK2,ATP1A2,SPARCL1,CTNND2,AQP4,GABBR2,SMOC1,NTM,PTPRT,SLC1A2,SPON1,GRID2,PTPRZ1,GRIA1,LAMA2,GRIA4
4.043e-02	-3.21	DAGKa	smart domains	SM00045	10	1	9717	40	DGKG
4.047e-02	-3.21	TNK2 (tyrosine kinase non receptor 2)	protein interactions	10188	124	2	19454	50	DCLK1,NTRK2
4.050e-02	-3.21	Lidocaine (Local Anaesthetic) Action Pathway	SMPDB pathways	SMP0000398	28	1	1369	2	ATP1A2
4.052e-02	-3.21	chloride transport	biological process	GO:0006821	121	2	18204	48	GABRB1,SLC1A3
4.055e-02	-3.21	muscle cell differentiation	biological process	GO:0042692	289	3	18204	48	QKI,PRKG1,DMD
4.059e-02	-3.20	ovary-carcinoma-mucinous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-mucinous_carcinoma	456	4	16828	48	PRKG1,DCLK1,TNIK,NTRK2
4.060e-02	-3.20	MAPK	prosite domains	PS01351	12	1	12186	42	MAPK10
4.060e-02	-3.20	CNMP_BINDING_2	prosite domains	PS00889	12	1	12186	42	PRKG1
4.067e-02	-3.20	neurexin family protein binding	molecular function	GO:0042043	15	1	18094	50	CPE
4.067e-02	-3.20	heparan sulfate sulfotransferase activity	molecular function	GO:0034483	15	1	18094	50	HS6ST3
4.076e-02	-3.20	positive regulation of biological process	biological process	GO:0048518	6326	23	18204	48	SPON1,GRIA1,PTPRZ1,GRID2,GPM6A,QKI,LIFR,LAMA2,SLC1A2,GLIS3,CLU,SASH1,GFAP,TNIK,PRKG1,SOX6,ATP1A2,ZBTB20,DMD,GPM6B,NTRK2,SLC1A3,NPAS3
4.093e-02	-3.20	Dilated cardiomyopathy	KEGG pathways	hsa05414	89	2	7161	26	LAMA2,DMD
4.093e-02	-3.20	Dilated cardiomyopathy	KEGG pathways	ko05414	89	2	7161	26	LAMA2,DMD
4.101e-02	-3.19	Ig-like_dom_sf	interpro domains	IPR036179	483	4	18521	50	LSAMP,NTRK2,PTPRT,NTM
4.106e-02	-3.19	SLAMF1 (signaling lymphocytic activation molecule family member 1)	protein interactions	6504	125	2	19454	50	LIFR,CPE
4.106e-02	-3.19	SCGB1D1 (secretoglobin family 1D member 1)	protein interactions	10648	125	2	19454	50	LIFR,CPE
4.114e-02	-3.19	mucinous_carcinoma	COSMIC cancer mutations	mucinous_carcinoma	458	4	16828	48	PRKG1,DCLK1,TNIK,NTRK2
4.118e-02	-3.19	lung-carcinoma	COSMIC cancer mutations	lung-carcinoma	4255	18	16828	48	PTPRZ1,LIFR,DMD,GRIA4,GPM6B,CTNNA3,QKI,PPP2R2B,PTPRT,CLU,TNIK,PRKG1,DCLK1,HS6ST3,CTNND2,PDZRN4,NTRK2,DGKG
4.138e-02	-3.18	glutamatergic neuron differentiation	biological process	GO:1905962	16	1	18204	48	GRID2
4.138e-02	-3.18	nonribosomal peptide biosynthetic process	biological process	GO:0019184	16	1	18204	48	SLC1A2
4.138e-02	-3.18	heparan sulfate proteoglycan metabolic process	biological process	GO:0030201	16	1	18204	48	HS6ST3
4.138e-02	-3.18	insulin metabolic process	biological process	GO:1901142	16	1	18204	48	CPE
4.138e-02	-3.18	response to lithium ion	biological process	GO:0010226	16	1	18204	48	GRIA1
4.138e-02	-3.18	locomotory exploration behavior	biological process	GO:0035641	16	1	18204	48	ATP1A2
4.138e-02	-3.18	regulation of respiratory system process	biological process	GO:0044065	16	1	18204	48	ATP1A2
4.138e-02	-3.18	cardiac left ventricle morphogenesis	biological process	GO:0003214	16	1	18204	48	CPE
4.138e-02	-3.18	regulation of amino acid transmembrane transport	biological process	GO:1903789	16	1	18204	48	ATP1A2
4.138e-02	-3.18	regulation of postsynaptic specialization assembly	biological process	GO:0099150	16	1	18204	48	GRID2
4.138e-02	-3.18	regulation of amino acid import across plasma membrane	biological process	GO:0010958	16	1	18204	48	ATP1A2
4.138e-02	-3.18	non-proteinogenic amino acid biosynthetic process	biological process	GO:0170043	16	1	18204	48	SLC1A3
4.152e-02	-3.18	calcium channel activity	molecular function	GO:0005262	117	2	18094	50	GRIA1,GPM6A
4.152e-02	-3.18	solute:monoatomic cation symporter activity	molecular function	GO:0015294	117	2	18094	50	SLC1A2,SLC1A3
4.166e-02	-3.18	SERPINA3 (serpin family A member 3)	protein interactions	12	126	2	19454	50	CLU,PPP2R2B
4.166e-02	-3.18	DAG1 (dystroglycan 1)	protein interactions	1605	126	2	19454	50	DMD,LAMA2
4.185e-02	-3.17	nitrogen compound transport	biological process	GO:0071705	1507	8	18204	48	SLC1A2,CPE,NTRK2,QKI,CLU,SLC1A3,GPM6B,GFAP
4.193e-02	-3.17	Codeine Action Pathway	SMPDB pathways	SMP0000405	29	1	1369	2	ATP1A2
4.196e-02	-3.17	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	48	QKI
4.226e-02	-3.16	DES (desmin)	protein interactions	1674	127	2	19454	50	GFAP,DTNA
4.231e-02	-3.16	Laminin_N	pfam domains	PF00055	16	1	17795	48	LAMA2
4.235e-02	-3.16	cNMP-bd_CS	interpro domains	IPR018488	16	1	18521	50	PRKG1
4.235e-02	-3.16	CarboxyPept-like_regulatory	interpro domains	IPR008969	16	1	18521	50	CPE
4.235e-02	-3.16	Laminin_N	interpro domains	IPR008211	16	1	18521	50	LAMA2
4.261e-02	-3.16	Morphine addiction	KEGG pathways	hsa05032	91	2	7161	26	GABBR2,GABRB1
4.261e-02	-3.16	Morphine addiction	KEGG pathways	ko05032	91	2	7161	26	GABBR2,GABRB1
4.271e-02	-3.15	GRB2 events in ERBB2 signaling	REACTOME pathways	R-HSA-1963640	16	1	10285	28	NRG3
4.271e-02	-3.15	Rap1 signalling	REACTOME pathways	R-HSA-392517	16	1	10285	28	PRKG1
4.271e-02	-3.15	PI3K events in ERBB2 signaling	REACTOME pathways	R-HSA-1963642	16	1	10285	28	NRG3
4.273e-02	-3.15	apical dendrite	cellular component	GO:0097440	17	1	19108	49	CLU
4.273e-02	-3.15	protein complex involved in cell-matrix adhesion	cellular component	GO:0098637	17	1	19108	49	LAMA2
4.282e-02	-3.15	ovary-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	ovary-carcinoma-endometrioid_carcinoma	464	4	16828	48	NTRK2,TNIK,DCLK1,PRKG1
4.282e-02	-3.15	UNC45B (unc-45 myosin chaperone B)	protein interactions	146862	17	1	19454	50	GRIA1
4.282e-02	-3.15	PAX4 (paired box 4)	protein interactions	5078	17	1	19454	50	NTM
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	GRID1 (glutamate ionotropic receptor delta type subunit 1)	protein interactions	2894	17	1	19454	50	GRIA1
4.282e-02	-3.15	TAGAP (T cell activation RhoGTPase activating protein)	protein interactions	117289	17	1	19454	50	DTNA
4.282e-02	-3.15	DPP6 (dipeptidyl peptidase like 6)	protein interactions	1804	17	1	19454	50	GPM6A
4.282e-02	-3.15	CLEC4M (C-type lectin domain family 4 member M)	protein interactions	10332	17	1	19454	50	GFAP
4.297e-02	-3.15	cerebral cortex development	biological process	GO:0021987	125	2	18204	48	NTRK2,GRIA1
4.297e-02	-3.15	memory	biological process	GO:0007613	125	2	18204	48	GRIA1,CSMD1
4.297e-02	-3.15	mammary gland development	biological process	GO:0030879	125	2	18204	48	CSMD1,NRG3
4.318e-02	-3.14	MAMDOMAIN	prints domains	PR00020	10	1	5227	23	PTPRT
4.333e-02	-3.14	misfolded protein binding	molecular function	GO:0051787	16	1	18094	50	CLU
4.333e-02	-3.14	MAP kinase kinase activity	molecular function	GO:0004708	16	1	18094	50	MAPK10
4.333e-02	-3.14	mitogen-activated protein kinase kinase kinase binding	molecular function	GO:0031435	16	1	18094	50	SASH1
4.333e-02	-3.14	cGMP binding	molecular function	GO:0030553	16	1	18094	50	PRKG1
4.333e-02	-3.14	MAP kinase activity	molecular function	GO:0004707	16	1	18094	50	MAPK10
4.333e-02	-3.14	water channel activity	molecular function	GO:0015250	16	1	18094	50	AQP4
4.336e-02	-3.14	Imipramine Action Pathway	SMPDB pathways	SMP0000422	30	1	1369	2	ATP1A2
4.346e-02	-3.14	CHD7 (chromodomain helicase DNA binding protein 7)	protein interactions	55636	129	2	19454	50	ZBTB20,SOX6
4.364e-02	-3.13	cellular response to organonitrogen compound	biological process	GO:0071417	505	4	18204	48	SLC1A3,GABRB1,SLC1A2,GRIA1
4.389e-02	-3.13	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	46	16828	48	GRID2,PTPRZ1,SPON1,GRIA4,LAMA2,GRIA1,SLC1A2,SMOC1,GABBR2,PTPRT,NTM,HS6ST3,CTNND2,AQP4,NTRK2,ATP1A2,SPARCL1,NPAS3,LIFR,NRG3,TNIK,GRIK1,GLIS3,CPE,DCLK1,PRKG1,SOX6,GABRB1,DTNA,ZBTB20,DGKG,PCDH9,LSAMP,MYO16,DMD,GFAP,PPP2R2B,QKI,CTNNA3,GPM6A,DPP6,CLU,SLC1A3,PHYHIPL,PDZRN4,SASH1
4.391e-02	-3.13	reverse cholesterol transport	biological process	GO:0043691	17	1	18204	48	CLU
4.391e-02	-3.13	regulation of postsynaptic density organization	biological process	GO:1905874	17	1	18204	48	GRID2
4.391e-02	-3.13	microvillus assembly	biological process	GO:0030033	17	1	18204	48	TNIK
4.391e-02	-3.13	regulation of amyloid fibril formation	biological process	GO:1905906	17	1	18204	48	CLU
4.391e-02	-3.13	negative regulation of smooth muscle cell apoptotic process	biological process	GO:0034392	17	1	18204	48	GRIA4
4.391e-02	-3.13	regulation of excitatory synapse assembly	biological process	GO:1904889	17	1	18204	48	GRID2
4.391e-02	-3.13	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	48	ATP1A2
4.391e-02	-3.13	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	48	CLU
4.391e-02	-3.13	protein trimerization	biological process	GO:0070206	17	1	18204	48	SLC1A2
4.391e-02	-3.13	retinal rod cell differentiation	biological process	GO:0060221	17	1	18204	48	NTRK2
4.391e-02	-3.13	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	48	ATP1A2
4.391e-02	-3.13	CARBOXYPEPT_ZN_1	prosite domains	PS00132	13	1	12186	42	CPE
4.391e-02	-3.13	CARBOXYPEPT_ZN_2	prosite domains	PS00133	13	1	12186	42	CPE
4.415e-02	-3.12	negative regulation of cellular process	biological process	GO:0048523	5320	20	18204	48	ATP1A2,QKI,ZBTB20,MYO16,SOX6,PRKG1,GFAP,GRIA1,PTPRZ1,CST3,NTRK2,DCLK1,CLU,GLIS3,NRG3,GRIA4,DGKG,DMD,GPM6B,PTPRT
4.455e-02	-3.11	-	gene3d domains	2.60.200.40	14	1	14470	47	DGKG
4.455e-02	-3.11	Glycerol uptake facilitator protein	gene3d domains	1.20.1080.10	14	1	14470	47	AQP4
4.479e-02	-3.11	Fluoxetine Action Pathway	SMPDB pathways	SMP0000426	31	1	1369	2	ATP1A2
4.490e-02	-3.10	Thyroglobulin_1	pfam domains	PF00086	17	1	17795	48	SMOC1
4.490e-02	-3.10	Cystatin	pfam domains	PF00031	17	1	17795	48	CST3
4.490e-02	-3.10	Carb_anhydrase	pfam domains	PF00194	17	1	17795	48	PTPRZ1
4.493e-02	-3.10	CA_dom	interpro domains	IPR001148	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	ATP-NAD_kinase_N	interpro domains	IPR017438	17	1	18521	50	DGKG
4.493e-02	-3.10	CA_dom_sf	interpro domains	IPR036398	17	1	18521	50	PTPRZ1
4.493e-02	-3.10	Thyroglobulin_1_sf	interpro domains	IPR036857	17	1	18521	50	SMOC1
4.493e-02	-3.10	NAD/diacylglycerol_kinase_sf	interpro domains	IPR016064	17	1	18521	50	DGKG
4.493e-02	-3.10	Thyroglobulin_1	interpro domains	IPR000716	17	1	18521	50	SMOC1
4.493e-02	-3.10	Cystatin_dom	interpro domains	IPR000010	17	1	18521	50	CST3
4.512e-02	-3.10	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	10	16828	48	NPAS3,GRID2,DPP6,PCDH9,TNIK,GPM6A,ZBTB20,LAMA2,GRIA4,PDZRN4
4.519e-02	-3.10	filopodium membrane	cellular component	GO:0031527	18	1	19108	49	DMD
4.519e-02	-3.10	protein phosphatase type 2A complex	cellular component	GO:0000159	18	1	19108	49	PPP2R2B
4.519e-02	-3.10	costamere	cellular component	GO:0043034	18	1	19108	49	DMD
4.519e-02	-3.10	dystrophin-associated glycoprotein complex	cellular component	GO:0016010	18	1	19108	49	DMD
4.529e-02	-3.09	CMC2 (C-X9-C motif containing 2)	protein interactions	56942	18	1	19454	50	CTNNA3
4.529e-02	-3.09	CYP2E1 (cytochrome P450 family 2 subfamily E member 1)	protein interactions	1571	18	1	19454	50	CLU
4.529e-02	-3.09	RAI2 (retinoic acid induced 2)	protein interactions	10742	18	1	19454	50	SOX6
4.529e-02	-3.09	SELL (selectin L)	protein interactions	6402	18	1	19454	50	PRKG1
4.529e-02	-3.09	OPCML (opioid binding protein/cell adhesion molecule like)	protein interactions	4978	18	1	19454	50	NTM
4.529e-02	-3.09	SERTAD4 (SERTA domain containing 4)	protein interactions	56256	18	1	19454	50	PPP2R2B
4.539e-02	-3.09	larynx	COSMIC cancer mutations	larynx	1948	10	16828	48	PCDH9,DPP6,TNIK,LAMA2,GRIA4,ZBTB20,GPM6A,PDZRN4,NPAS3,GRID2
4.553e-02	-3.09	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	48	TNIK,ATP1A2,PTPRT
4.575e-02	-3.08	Oxidative Stress Induced Senescence	REACTOME pathways	R-HSA-2559580	126	2	10285	28	TNIK,MAPK10
4.597e-02	-3.08	myosin V binding	molecular function	GO:0031489	17	1	18094	50	GRIA1
4.597e-02	-3.08	ligand-gated sodium channel activity	molecular function	GO:0015280	17	1	18094	50	GRIK1
4.598e-02	-3.08	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	120	2	16828	48	PTPRT,CTNND2
4.622e-02	-3.07	Nicotine Action Pathway	SMPDB pathways	SMP0000431	32	1	1369	2	ATP1A2
4.622e-02	-3.07	Methadone Action Pathway	SMPDB pathways	SMP0000408	32	1	1369	2	ATP1A2
4.622e-02	-3.07	Citalopram Action Pathway	SMPDB pathways	SMP0000424	32	1	1369	2	ATP1A2
4.629e-02	-3.07	parathyroid	COSMIC cancer mutations	parathyroid	476	4	16828	48	GPM6A,PRKG1,GRIA4,SOX6
4.633e-02	-3.07	positive regulation of cellular component biogenesis	biological process	GO:0044089	515	4	18204	48	GPM6A,NTRK2,CLU,GRID2
4.643e-02	-3.07	positive regulation of circadian rhythm	biological process	GO:0042753	18	1	18204	48	PRKG1
4.643e-02	-3.07	negative regulation of anoikis	biological process	GO:2000811	18	1	18204	48	NTRK2
4.643e-02	-3.07	regulation of extracellular matrix disassembly	biological process	GO:0010715	18	1	18204	48	CST3
4.643e-02	-3.07	negative regulation of lyase activity	biological process	GO:0051350	18	1	18204	48	GABBR2
4.643e-02	-3.07	response to misfolded protein	biological process	GO:0051788	18	1	18204	48	CLU
4.643e-02	-3.07	regulation of protein kinase C signaling	biological process	GO:0090036	18	1	18204	48	DGKG
4.643e-02	-3.07	negative regulation of platelet activation	biological process	GO:0010544	18	1	18204	48	PRKG1
4.643e-02	-3.07	negative regulation of sodium ion transport	biological process	GO:0010766	18	1	18204	48	ATP1A2
4.643e-02	-3.07	myelin maintenance	biological process	GO:0043217	18	1	18204	48	CLU
4.643e-02	-3.07	dendritic spine morphogenesis	biological process	GO:0060997	18	1	18204	48	CTNND2
4.643e-02	-3.07	positive regulation of sodium ion transmembrane transport	biological process	GO:1902307	18	1	18204	48	DMD
4.643e-02	-3.07	regulation of skeletal muscle contraction	biological process	GO:0014819	18	1	18204	48	DMD
4.653e-02	-3.07	H3-7 (H3.7 histone (putative))	protein interactions	440686	134	2	19454	50	PPP2R2B,LAMA2
4.655e-02	-3.07	ATP binding	molecular function	GO:0005524	1467	8	18094	50	TNIK,MYO16,NTRK2,DCLK1,PRKG1,MAPK10,DGKG,ATP1A2
4.677e-02	-3.06	human chr10q21.3	chromosome location	human chr10q21.3	25	1	26134	50	CTNNA3
4.715e-02	-3.05	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	48	DTNA,QKI,GRIA4
4.716e-02	-3.05	FAM83H (family with sequence similarity 83 member H)	protein interactions	286077	135	2	19454	50	GFAP,PPP2R2B
4.716e-02	-3.05	NTRK2 (neurotrophic receptor tyrosine kinase 2)	protein interactions	4915	135	2	19454	50	NTRK2,DTNA
4.716e-02	-3.05	FOXP1 (forkhead box P1)	protein interactions	27086	135	2	19454	50	SOX6,SASH1
4.739e-02	-3.05	inorganic anion transmembrane transport	biological process	GO:0098661	132	2	18204	48	GABRB1,SLC1A3
4.742e-02	-3.05	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	48	QKI
4.742e-02	-3.05	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	48	QKI
4.748e-02	-3.05	Cation_ATPase_N	pfam domains	PF00690	18	1	17795	48	ATP1A2
4.748e-02	-3.05	MAM	pfam domains	PF00629	18	1	17795	48	PTPRT
4.752e-02	-3.05	ATPase_P-typ_cation-transptr_N	interpro domains	IPR004014	18	1	18521	50	ATP1A2
4.752e-02	-3.05	MAM_dom	interpro domains	IPR000998	18	1	18521	50	PTPRT
4.764e-02	-3.04	GABA-A receptor complex	cellular component	GO:1902711	19	1	19108	49	GABRB1
4.764e-02	-3.04	cation-transporting ATPase complex	cellular component	GO:0090533	19	1	19108	49	ATP1A2
4.774e-02	-3.04	PDP2 (pyruvate dehydrogenase phosphatase catalytic subunit 2)	protein interactions	57546	19	1	19454	50	GFAP
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	DTNA
4.774e-02	-3.04	PLA2G4E (phospholipase A2 group IVE)	protein interactions	123745	19	1	19454	50	PPP2R2B
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	CDH3 (cadherin 3)	protein interactions	1001	19	1	19454	50	CTNNA3
4.774e-02	-3.04	FBXO27 (F-box protein 27)	protein interactions	126433	19	1	19454	50	CLU
4.774e-02	-3.04	OSM (oncostatin M)	protein interactions	5008	19	1	19454	50	LIFR
4.774e-02	-3.04	Trp53 (transformation related protein 53)	protein interactions	22059	19	1	19454	50	MAPK10
4.774e-02	-3.04	C3orf62 (chromosome 3 open reading frame 62)	protein interactions	375341	19	1	19454	50	ATP1A2
4.774e-02	-3.04	SPZ1 (spermatogenic leucine zipper 1)	protein interactions	84654	19	1	19454	50	DTNA
4.774e-02	-3.04	KCNF1 (potassium voltage-gated channel modifier subfamily F member 1)	protein interactions	3754	19	1	19454	50	GFAP
4.774e-02	-3.04	LONRF3 (LON peptidase N-terminal domain and ring finger 3)	protein interactions	79836	19	1	19454	50	DMD
4.774e-02	-3.04	TNR (tenascin R)	protein interactions	7143	19	1	19454	50	PTPRZ1
4.784e-02	-3.04	regulation of monoatomic cation transmembrane transport	biological process	GO:1904062	309	3	18204	48	DPP6,DMD,ATP1A2
4.792e-02	-3.04	cGMP effects	REACTOME pathways	R-HSA-418457	18	1	10285	28	PRKG1
4.802e-02	-3.04	ductal_carcinoma	COSMIC cancer mutations	ductal_carcinoma	15798	48	16828	48	LAMA2,GRIA4,GRIA1,GRID2,PTPRZ1,SPON1,SLC1A2,PTPRT,NTM,SMOC1,GABBR2,AQP4,CTNND2,SPARCL1,NTRK2,ATP1A2,HS6ST3,GLIS3,CPE,NRG3,TNIK,GRIK1,LIFR,NPAS3,ZBTB20,PCDH9,DGKG,DCLK1,PRKG1,SOX6,GABRB1,DTNA,GPM6A,GPM6B,GFAP,QKI,CTNNA3,PPP2R2B,DPP6,CLU,MYO16,LSAMP,CST3,DMD,PDZRN4,SASH1,SLC1A3,PHYHIPL
4.804e-02	-3.04	regulation of sequestering of calcium ion	biological process	GO:0051282	133	2	18204	48	DMD,ATP1A2
4.826e-02	-3.03	ovary-carcinoma	COSMIC cancer mutations	ovary-carcinoma	933	6	16828	48	DCLK1,PRKG1,PPP2R2B,NTRK2,ATP1A2,TNIK
4.828e-02	-3.03	seminoma	COSMIC cancer mutations	seminoma	700	5	16828	48	TNIK,NTRK2,PRKG1,LAMA2,DCLK1
4.842e-02	-3.03	TBL1X (transducin beta like 1 X-linked)	protein interactions	6907	137	2	19454	50	SOX6,DGKG
4.859e-02	-3.02	human chr18q12.1	chromosome location	human chr18q12.1	26	1	26134	50	DTNA
4.859e-02	-3.02	human chr14q24.2	chromosome location	human chr14q24.2	26	1	26134	50	SMOC1
4.861e-02	-3.02	adrenergic receptor binding	molecular function	GO:0031690	18	1	18094	50	GRIA1
4.861e-02	-3.02	transmembrane receptor protein tyrosine kinase activator activity	molecular function	GO:0030297	18	1	18094	50	NRG3
4.861e-02	-3.02	GABA receptor binding	molecular function	GO:0050811	18	1	18094	50	GABRB1
4.895e-02	-3.02	microvillus organization	biological process	GO:0032528	19	1	18204	48	TNIK
4.895e-02	-3.02	vascular associated smooth muscle cell differentiation	biological process	GO:0035886	19	1	18204	48	QKI
4.895e-02	-3.02	excitatory synapse assembly	biological process	GO:1904861	19	1	18204	48	GRID2
4.895e-02	-3.02	regulation of glutamate secretion	biological process	GO:0014048	19	1	18204	48	PRKG1
4.895e-02	-3.02	negative regulation of alcohol biosynthetic process	biological process	GO:1902931	19	1	18204	48	PRKG1
4.895e-02	-3.02	response to potassium ion	biological process	GO:0035864	19	1	18204	48	ATP1A2
4.895e-02	-3.02	regulation of amyloid-beta clearance	biological process	GO:1900221	19	1	18204	48	CLU
4.895e-02	-3.02	cartilage condensation	biological process	GO:0001502	19	1	18204	48	SOX6
4.895e-02	-3.02	long-term synaptic depression	biological process	GO:0060292	19	1	18204	48	GRIA1
4.907e-02	-3.01	Indapamide Action Pathway	SMPDB pathways	SMP0000110	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Trichlormethiazide Action Pathway	SMPDB pathways	SMP0000121	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Furosemide Action Pathway	SMPDB pathways	SMP0000115	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Eplerenone Action Pathway	SMPDB pathways	SMP0000135	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Torsemide Action Pathway	SMPDB pathways	SMP0000118	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Quinethazone Action Pathway	SMPDB pathways	SMP0000091	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Chlorothiazide Action Pathway	SMPDB pathways	SMP0000078	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Ethacrynic Acid Action Pathway	SMPDB pathways	SMP0000097	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Iminoglycinuria	SMPDB pathways	SMP0000193	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Blue Diaper Syndrome	SMPDB pathways	SMP0000583	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Bendroflumethiazide Action Pathway	SMPDB pathways	SMP0000090	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Cyclothiazide Action Pathway	SMPDB pathways	SMP0000103	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Polythiazide Action Pathway	SMPDB pathways	SMP0000080	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Glucose Transporter Defect (SGLT2)	SMPDB pathways	SMP0000184	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Bumetanide Action Pathway	SMPDB pathways	SMP0000088	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Metolazone Action Pathway	SMPDB pathways	SMP0000105	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Hydrochlorothiazide Action Pathway	SMPDB pathways	SMP0000100	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Hartnup Disorder	SMPDB pathways	SMP0000189	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Lysinuric Protein Intolerance (LPI)	SMPDB pathways	SMP0000585	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Triamterene Action Pathway	SMPDB pathways	SMP0000132	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Hydroflumethiazide Action Pathway	SMPDB pathways	SMP0000108	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Chlorthalidone Action Pathway	SMPDB pathways	SMP0000122	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Cystinuria	SMPDB pathways	SMP0000723	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Lysinuric Protein Intolerance	SMPDB pathways	SMP0000197	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Methyclothiazide Action Pathway	SMPDB pathways	SMP0000081	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Kidney Function	SMPDB pathways	SMP0000483	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Spironolactone Action Pathway	SMPDB pathways	SMP0000134	34	1	1369	2	ATP1A2
4.907e-02	-3.01	Amiloride Action Pathway	SMPDB pathways	SMP0000133	34	1	1369	2	ATP1A2
4.958e-02	-3.00	regulation of cellular component biogenesis	biological process	GO:0044087	1016	6	18204	48	GPM6A,GPM6B,GFAP,GRID2,NTRK2,CLU
4.959e-02	-3.00	Choline metabolism in cancer	KEGG pathways	hsa05231	99	2	7161	26	MAPK10,DGKG
4.959e-02	-3.00	Choline metabolism in cancer	KEGG pathways	ko05231	99	2	7161	26	DGKG,MAPK10
4.961e-02	-3.00	testis-germ_cell_tumour-non_seminoma	COSMIC cancer mutations	testis-germ_cell_tumour-non_seminoma	487	4	16828	48	PRKG1,DCLK1,TNIK,NTRK2
4.968e-02	-3.00	HOMEZ (homeobox and leucine zipper encoding)	protein interactions	57594	139	2	19454	50	CTNNA3,GFAP
4.968e-02	-3.00	NEFM (neurofilament medium chain)	protein interactions	4741	139	2	19454	50	GFAP,TNIK
4.999e-02	-3.00	protein dephosphorylation	biological process	GO:0006470	136	2	18204	48	PTPRT,PTPRZ1