Fibroblasts

Fibroblasts are the most common cells of connective tissue. They synthesize and secrete the extracellular matrix (ECM) components, including collagen, elastin, and fibronectin, providing structural and biochemical support to surrounding cells. They are key players in wound healing, where they proliferate, migrate to the injury site, and differentiate into contractile myofibroblasts to close wounds. They also communicate with immune and epithelial cells.