TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
R-HSA-6794361	Interactions of neurexins and neuroligins at synapses	0.000560391456795296	-7.48687498845114	58	3	0.103448275862069	29	10285	347731,9369,22871	LRRTM3,NRXN3,NLGN1
R-HSA-2162123	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	0.000787945571660247	-7.14608154198909	15	2	0.0689655172413793	29	10285	5730,873	PTGDS,CBR1
R-HSA-6794362	Protein-protein interactions at synapses	0.00105483425083063	-6.85437163261431	72	3	0.103448275862069	29	10285	9369,22871,347731	NRXN3,NLGN1,LRRTM3
R-HSA-3000480	Scavenging by Class A Receptors	0.00155944965470575	-6.46342230540915	21	2	0.0689655172413793	29	10285	2512,2495	FTL,FTH1
R-HSA-2173782	Binding and Uptake of Ligands by Scavenger Receptors	0.00645317988937603	-5.04318226355723	43	2	0.0689655172413793	29	10285	2512,2495	FTL,FTH1
R-HSA-917937	Iron uptake and transport	0.00674871258722278	-4.99840352010741	44	2	0.0689655172413793	29	10285	2512,2495	FTL,FTH1
R-HSA-432722	Golgi Associated Vesicle Biogenesis	0.0111312091532773	-4.49800248048701	57	2	0.0689655172413793	29	10285	2512,2495	FTL,FTH1
R-HSA-2142753	Arachidonic acid metabolism	0.0118918766898298	-4.4318997430701	59	2	0.0689655172413793	29	10285	5730,873	PTGDS,CBR1
R-HSA-1300652	Sperm:Oocyte Membrane Binding	0.0140216329141271	-4.26715393382067	5	1	0.0344827586206897	29	10285	928	CD9
R-HSA-5336415	Uptake and function of diphtheria toxin	0.0168030893966375	-4.08619251682211	6	1	0.0344827586206897	29	10285	928	CD9
R-HSA-199992	trans-Golgi Network Vesicle Budding	0.0178268855900003	-4.02704753482622	73	2	0.0689655172413793	29	10285	2512,2495	FTL,FTH1
R-HSA-421837	Clathrin derived vesicle budding	0.0178268855900003	-4.02704753482622	73	2	0.0689655172413793	29	10285	2512,2495	FTL,FTH1
R-HSA-193634	Axonal growth inhibition (RHOA activation)	0.0223432922008268	-3.8012291282118	8	1	0.0344827586206897	29	10285	4974	OMG
R-HSA-1253288	Downregulation of ERBB4 signaling	0.0223432922008268	-3.8012291282118	8	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-804914	Transport of fatty acids	0.0223432922008268	-3.8012291282118	8	1	0.0344827586206897	29	10285	347	APOD
R-HSA-5663205	Infectious disease	0.0224619106854507	-3.79593426270017	388	4	0.137931034482759	29	10285	567,928,6158,6135	B2M,CD9,RPL28,RPL11
R-HSA-193697	p75NTR regulates axonogenesis	0.0251020782796419	-3.68480463628639	9	1	0.0344827586206897	29	10285	4974	OMG
R-HSA-192823	Viral mRNA Translation	0.027476947321005	-3.59440790509831	92	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-156902	Peptide chain elongation	0.027476947321005	-3.59440790509831	92	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-1250342	PI3K events in ERBB4 signaling	0.027853347229444	-3.58080213205904	10	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-164940	Nef mediated downregulation of MHC class I complex cell surface expression	0.027853347229444	-3.58080213205904	10	1	0.0344827586206897	29	10285	567	B2M
R-HSA-2408557	Selenocysteine synthesis	0.0291567977276018	-3.53506719516965	95	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-72764	Eukaryotic Translation Termination	0.0297257723352906	-3.51574085405854	96	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-156842	Eukaryotic Translation Elongation	0.0297257723352906	-3.51574085405854	96	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-975956	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	0.0314593786198218	-3.45905813298312	99	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-977225	Amyloid fiber formation	0.0326370747916221	-3.42230637325709	101	2	0.0689655172413793	29	10285	9445,567	ITM2B,B2M
R-HSA-1236977	Endosomal/Vacuolar pathway	0.0333334127068286	-3.40119500046013	12	1	0.0344827586206897	29	10285	567	B2M
R-HSA-72689	Formation of a pool of free 40S subunits	0.0350441816311426	-3.35114568124594	105	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-8847993	ERBB2 Activates PTK6 Signaling	0.0360622485903299	-3.32250870623677	13	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-1474228	Degradation of the extracellular matrix	0.0387808899835024	-3.24982767988217	111	2	0.0689655172413793	29	10285	825,6696	CAPN3,SPP1
R-HSA-6803205	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	0.0387836460579566	-3.24975661455783	14	1	0.0344827586206897	29	10285	79370	BCL2L14
R-HSA-1250347	SHC1 events in ERBB4 signaling	0.0387836460579566	-3.24975661455783	14	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-1799339	SRP-dependent cotranslational protein targeting to membrane	0.041353582845841	-3.18559621445007	115	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-6785631	ERBB2 Regulates Cell Motility	0.0414976246648919	-3.18211909037414	15	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-156827	L13a-mediated translational silencing of Ceruloplasmin expression	0.0426637685152332	-3.15440523146189	117	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-72706	GTP hydrolysis and joining of the 60S ribosomal subunit	0.0426637685152332	-3.15440523146189	117	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-1963642	PI3K events in ERBB2 signaling	0.0442042039133976	-3.11893538325842	16	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-1963640	GRB2 events in ERBB2 signaling	0.0442042039133976	-3.11893538325842	16	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-927802	Nonsense-Mediated Decay (NMD)	0.0446582672254765	-3.10871583257325	120	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-975957	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	0.0446582672254765	-3.10871583257325	120	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-2408522	Selenoamino acid metabolism	0.0453307903222239	-3.09376877932092	121	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-6798695	Neutrophil degranulation	0.0461713165960965	-3.07539652660176	487	4	0.137931034482759	29	10285	2512,4718,2495,567	FTL,NDUFC2,FTH1,B2M
R-HSA-198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	0.0473710769511985	-3.04974342742633	124	2	0.0689655172413793	29	10285	567,975	B2M,CD81
R-HSA-72737	Cap-dependent Translation Initiation	0.0480586615189594	-3.03533289927056	125	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-72613	Eukaryotic Translation Initiation	0.0480586615189594	-3.03533289927056	125	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-418457	cGMP effects	0.0495952421097025	-3.00386037505998	18	1	0.0344827586206897	29	10285	8654	PDE5A
R-HSA-1474244	Extracellular matrix organization	0.0496859244859187	-3.00203359552981	296	3	0.103448275862069	29	10285	825,6696,3908	CAPN3,SPP1,LAMA2
R-HSA-8874081	MET activates PTK2 signaling	0.0549569156944012	-2.90120575174028	20	1	0.0344827586206897	29	10285	3908	LAMA2
R-HSA-168273	Influenza Viral RNA Transcription and Replication	0.0565915170866339	-2.8718961797998	137	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-164938	Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	0.0602893789331553	-2.80859932785823	22	1	0.0344827586206897	29	10285	567	B2M
R-HSA-1250196	SHC1 events in ERBB2 signaling	0.0602893789331553	-2.80859932785823	22	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-168255	Influenza Life Cycle	0.0633160080008216	-2.75961709079531	146	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-392154	Nitric oxide stimulates guanylate cyclase	0.0655927853104418	-2.72428956910409	24	1	0.0344827586206897	29	10285	8654	PDE5A
R-HSA-201451	Signaling by BMP	0.0655927853104418	-2.72428956910409	24	1	0.0344827586206897	29	10285	9765	ZFYVE16
R-HSA-1251985	Nuclear signaling by ERBB4	0.0682336399289175	-2.68481758165283	25	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-3000157	Laminin interactions	0.0682336399289175	-2.68481758165283	25	1	0.0344827586206897	29	10285	3908	LAMA2
R-HSA-983170	Antigen Presentation: Folding, assembly and peptide loading of class I MHC	0.0682336399289175	-2.68481758165283	25	1	0.0344827586206897	29	10285	567	B2M
R-HSA-1474165	Reproduction	0.0708672875342895	-2.64694634071366	26	1	0.0344827586206897	29	10285	928	CD9
R-HSA-1187000	Fertilization	0.0708672875342895	-2.64694634071366	26	1	0.0344827586206897	29	10285	928	CD9
R-HSA-168254	Influenza Infection	0.0718857786964646	-2.63267682663562	157	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-112316	Neuronal System	0.0739105148427253	-2.60490017640355	349	3	0.103448275862069	29	10285	347731,22871,9369	LRRTM3,NLGN1,NRXN3
R-HSA-72766	Translation	0.0759013167998606	-2.57832124558927	162	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-164952	The role of Nef in HIV-1 replication and disease pathogenesis	0.0787251777262849	-2.5417922544392	29	1	0.0344827586206897	29	10285	567	B2M
R-HSA-375170	CDO in myogenesis	0.0787251777262849	-2.5417922544392	29	1	0.0344827586206897	29	10285	1496	CTNNA2
R-HSA-525793	Myogenesis	0.0787251777262849	-2.5417922544392	29	1	0.0344827586206897	29	10285	1496	CTNNA2
R-HSA-8863795	Downregulation of ERBB2 signaling	0.0813301864883494	-2.50923803382257	30	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-445095	Interaction between L1 and Ankyrins	0.0813301864883494	-2.50923803382257	30	1	0.0344827586206897	29	10285	288	ANK3
R-HSA-8875878	MET promotes cell motility	0.0839280825960304	-2.47779500642382	31	1	0.0344827586206897	29	10285	3908	LAMA2
R-HSA-418990	Adherens junctions interactions	0.0839280825960304	-2.47779500642382	31	1	0.0344827586206897	29	10285	253559	CADM2
R-HSA-5339562	Uptake and actions of bacterial toxins	0.0839280825960304	-2.47779500642382	31	1	0.0344827586206897	29	10285	928	CD9
R-HSA-1643685	Disease	0.0891047970290606	-2.41794210724463	858	5	0.172413793103448	29	10285	2066,6158,6135,928,567	ERBB4,RPL28,RPL11,CD9,B2M
R-HSA-6791226	Major pathway of rRNA processing in the nucleolus and cytosol	0.0900721498220547	-2.40714426512388	179	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-8868773	rRNA processing in the nucleus and cytosol	0.100516976815883	-2.29742864220786	191	2	0.0689655172413793	29	10285	6135,6158	RPL11,RPL28
R-HSA-425397	Transport of vitamins, nucleosides, and related molecules	0.106992152812227	-2.23499978541309	40	1	0.0344827586206897	29	10285	347	APOD
R-HSA-72312	rRNA processing	0.109472603690069	-2.21208095564071	201	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-1236394	Signaling by ERBB4	0.114554818897942	-2.1667018028929	43	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-3000171	Non-integrin membrane-ECM interactions	0.119562201664388	-2.12391852701206	45	1	0.0344827586206897	29	10285	3908	LAMA2
R-HSA-5633008	TP53 Regulates Transcription of Cell Death Genes	0.119562201664388	-2.12391852701206	45	1	0.0344827586206897	29	10285	79370	BCL2L14
R-HSA-6799198	Complex I biogenesis	0.134420845311673	-2.00677976387452	51	1	0.0344827586206897	29	10285	4718	NDUFC2
R-HSA-1227986	Signaling by ERBB2	0.134420845311673	-2.00677976387452	51	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-3000178	ECM proteoglycans	0.149037233892937	-1.90355911235555	57	1	0.0344827586206897	29	10285	3908	LAMA2
R-HSA-421270	Cell-cell junction organization	0.158648791110488	-1.84106238083391	61	1	0.0344827586206897	29	10285	253559	CADM2
R-HSA-2219530	Constitutive Signaling by Aberrant PI3K in Cancer	0.168155489176472	-1.7828661968061	65	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-8848021	Signaling by PTK6	0.172869861331893	-1.75521621420029	67	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-216083	Integrin cell surface interactions	0.175217363193868	-1.74172800040259	68	1	0.0344827586206897	29	10285	6696	SPP1
R-HSA-6806834	Signaling by MET	0.177558431653386	-1.72845553182516	69	1	0.0344827586206897	29	10285	3908	LAMA2
R-HSA-446203	Asparagine N-linked glycosylation	0.190331329543781	-1.65898888584065	284	2	0.0689655172413793	29	10285	288,1603	ANK3,DAD1
R-HSA-6807878	COPI-mediated anterograde transport	0.200618998543544	-1.60634769934693	79	1	0.0344827586206897	29	10285	288	ANK3
R-HSA-1236974	ER-Phagosome pathway	0.214154327428049	-1.54105836766264	85	1	0.0344827586206897	29	10285	567	B2M
R-HSA-6811558	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	0.218616727760447	-1.52043518393294	87	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-446728	Cell junction organization	0.220838743345564	-1.51032251192135	88	1	0.0344827586206897	29	10285	253559	CADM2
R-HSA-2219528	PI3K/AKT Signaling in Cancer	0.225264486330501	-1.49048007232856	90	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-418346	Platelet homeostasis	0.227468246004695	-1.48074462833439	91	1	0.0344827586206897	29	10285	8654	PDE5A
R-HSA-611105	Respiratory electron transport	0.229665952580845	-1.47112940586851	92	1	0.0344827586206897	29	10285	4718	NDUFC2
R-HSA-5625740	RHO GTPases activate PKNs	0.231857622101582	-1.46163179354344	93	1	0.0344827586206897	29	10285	94274	PPP1R14A
R-HSA-199418	Negative regulation of the PI3K/AKT network	0.234043270541738	-1.45224926387441	94	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-877300	Interferon gamma signaling	0.234043270541738	-1.45224926387441	94	1	0.0344827586206897	29	10285	567	B2M
R-HSA-193704	p75 NTR receptor-mediated signalling	0.240564248782785	-1.42476807840768	97	1	0.0344827586206897	29	10285	4974	OMG
R-HSA-199991	Membrane Trafficking	0.24553097580476	-1.4043321653494	610	3	0.103448275862069	29	10285	2512,2495,288	FTL,FTH1,ANK3
R-HSA-1236975	Antigen processing-Cross presentation	0.249175554571936	-1.38959759249876	101	1	0.0344827586206897	29	10285	567	B2M
R-HSA-373760	L1CAM interactions	0.249175554571936	-1.38959759249876	101	1	0.0344827586206897	29	10285	288	ANK3
R-HSA-2424491	DAP12 signaling	0.26560644873324	-1.32573958180548	356	2	0.0689655172413793	29	10285	2066,567	ERBB4,B2M
R-HSA-71291	Metabolism of amino acids and derivatives	0.270893029027732	-1.30603126286252	361	2	0.0689655172413793	29	10285	6158,6135	RPL28,RPL11
R-HSA-163200	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	0.274447562540746	-1.29299506527638	113	1	0.0344827586206897	29	10285	4718	NDUFC2
R-HSA-5653656	Vesicle-mediated transport	0.276482362615825	-1.28560824806216	650	3	0.103448275862069	29	10285	2512,2495,288	FTL,FTH1,ANK3
R-HSA-2172127	DAP12 interactions	0.281469085851031	-1.26773265678989	371	2	0.0689655172413793	29	10285	2066,567	ERBB4,B2M
R-HSA-186797	Signaling by PDGF	0.286756510138678	-1.24912182004405	376	2	0.0689655172413793	29	10285	2066,6696	ERBB4,SPP1
R-HSA-168249	Innate Immune System	0.292567640536951	-1.22905938934534	1285	5	0.172413793103448	29	10285	2495,4718,2512,2066,567	FTH1,NDUFC2,FTL,ERBB4,B2M
R-HSA-382551	Transmembrane transport of small molecules	0.297658155297632	-1.21180958080753	677	3	0.103448275862069	29	10285	2495,347,2512	FTH1,APOD,FTL
R-HSA-1257604	PIP3 activates AKT signaling	0.298897314709183	-1.207655193643	125	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-392499	Metabolism of proteins	0.300906711139294	-1.20095499204121	1619	6	0.206896551724138	29	10285	567,6158,1603,6135,288,9445	B2M,RPL28,DAD1,RPL11,ANK3,ITM2B
R-HSA-198203	PI3K/AKT activation	0.304884319338543	-1.18782285517714	128	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-180292	GAB1 signalosome	0.304884319338543	-1.18782285517714	128	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-2730905	Role of LAT2/NTAL/LAB on calcium mobilization	0.310821946856341	-1.16853504890081	131	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-114608	Platelet degranulation	0.312790251329206	-1.16222243662399	132	1	0.0344827586206897	29	10285	928	CD9
R-HSA-1500931	Cell-Cell communication	0.314753127594423	-1.15596666934955	133	1	0.0344827586206897	29	10285	253559	CADM2
R-HSA-199977	ER to Golgi Anterograde Transport	0.314753127594423	-1.15596666934955	133	1	0.0344827586206897	29	10285	288	ANK3
R-HSA-162909	Host Interactions of HIV factors	0.316710590098668	-1.14976688709965	134	1	0.0344827586206897	29	10285	567	B2M
R-HSA-76005	Response to elevated platelet cytosolic Ca2+	0.322550638818181	-1.13149513548134	137	1	0.0344827586206897	29	10285	928	CD9
R-HSA-1428517	The citric acid (TCA) cycle and respiratory electron transport	0.36210245456807	-1.01582808353131	158	1	0.0344827586206897	29	10285	4718	NDUFC2
R-HSA-948021	Transport to the Golgi and subsequent modification	0.372987179016098	-0.986211232540072	164	1	0.0344827586206897	29	10285	288	ANK3
R-HSA-166520	Signalling by NGF	0.392025115611614	-0.936429370806307	477	2	0.0689655172413793	29	10285	4974,2066	OMG,ERBB4
R-HSA-1280218	Adaptive Immune System	0.402793762106848	-0.909330604586225	810	3	0.103448275862069	29	10285	567,2066,975	B2M,ERBB4,CD81
R-HSA-1168372	Downstream signaling events of B Cell Receptor (BCR)	0.429721318627084	-0.844618376615749	197	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-913531	Interferon Signaling	0.436251589721248	-0.829536161411971	201	1	0.0344827586206897	29	10285	567	B2M
R-HSA-422475	Axon guidance	0.463283253523978	-0.769416633286686	549	2	0.0689655172413793	29	10285	2066,288	ERBB4,ANK3
R-HSA-983705	Signaling by the B Cell Receptor (BCR)	0.479983703445094	-0.734003126812608	229	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-162906	HIV Infection	0.490393942483924	-0.712546246630707	236	1	0.0344827586206897	29	10285	567	B2M
R-HSA-180336	SHC1 events in EGFR signaling	0.503483192893306	-0.686204947930205	245	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-179812	GRB2 events in EGFR signaling	0.503483192893306	-0.686204947930205	245	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-112412	SOS-mediated signalling	0.503483192893306	-0.686204947930205	245	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-5673001	RAF/MAP kinase cascade	0.503483192893306	-0.686204947930205	245	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-187706	Signalling to p38 via RIT and RIN	0.509195883945485	-0.674922495706488	249	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-170984	ARMS-mediated activation	0.509195883945485	-0.674922495706488	249	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-170968	Frs2-mediated activation	0.510614110274001	-0.672141139864064	250	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-5684996	MAPK1/MAPK3 signaling	0.512028379407485	-0.669375226948489	251	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-169893	Prolonged ERK activation events	0.51343870200996	-0.666624629650508	252	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-2586552	Signaling by Leptin	0.514845088710329	-0.6638892221881	253	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-912526	Interleukin receptor SHC signaling	0.517646096688431	-0.658463481243859	255	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-167044	Signalling to RAS	0.519040739067384	-0.655772903583967	256	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-5218921	VEGFR2 mediated cell proliferation	0.521818353231835	-0.650435733973887	258	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-451927	Interleukin-2 signaling	0.527327191551353	-0.639934066258956	262	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-187687	Signalling to ERKs	0.528694797212952	-0.637343956506096	263	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-2871796	FCERI mediated MAPK activation	0.531418556134776	-0.632205326930795	265	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-8853659	RET signaling	0.538161626498007	-0.619596342937693	270	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-512988	Interleukin-3, 5 and GM-CSF signaling	0.539498951790365	-0.617114437213796	271	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-109582	Hemostasis	0.539546900318221	-0.617025565127789	632	2	0.0689655172413793	29	10285	928,8654	CD9,PDE5A
R-HSA-375165	NCAM signaling for neurite out-growth	0.546129690402474	-0.604898803232931	276	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-76002	Platelet activation, signaling and aggregation	0.553964943167084	-0.590653873718882	282	1	0.0344827586206897	29	10285	928	CD9
R-HSA-168256	Immune System	0.559618622134932	-0.580499759162418	2101	6	0.206896551724138	29	10285	567,2066,975,2512,2495,4718	B2M,ERBB4,CD81,FTL,FTH1,NDUFC2
R-HSA-425407	SLC-mediated transmembrane transport	0.560394409475566	-0.579114440522711	287	1	0.0344827586206897	29	10285	347	APOD
R-HSA-5683057	MAPK family signaling cascades	0.564209038693468	-0.5723304601713	290	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-112399	IRS-mediated signalling	0.569245525841891	-0.563443433811133	294	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-195258	RHO GTPase Effectors	0.569245525841891	-0.563443433811133	294	1	0.0344827586206897	29	10285	94274	PPP1R14A
R-HSA-74751	Insulin receptor signalling cascade	0.572985961926637	-0.556894061822943	297	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-2428924	IGF1R signaling cascade	0.574225790436553	-0.554732596879681	298	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-2428928	IRS-related events triggered by IGF1R	0.574225790436553	-0.554732596879681	298	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-2404192	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	0.575462142918791	-0.552581834184937	299	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-1266738	Developmental Biology	0.596708846688769	-0.516325978539589	1075	3	0.103448275862069	29	10285	288,1496,2066	ANK3,CTNNA2,ERBB4
R-HSA-74752	Signaling by Insulin receptor	0.602960173071256	-0.505904132410914	322	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-4420097	VEGFA-VEGFR2 Pathway	0.612115245139301	-0.490834705146589	330	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-1433557	Signaling by SCF-KIT	0.619958451964678	-0.478102816148666	337	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-194138	Signaling by VEGF	0.621066333440618	-0.476317385618552	338	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-186763	Downstream signal transduction	0.636253043367588	-0.452158927839904	352	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-1280215	Cytokine Signaling in Immune system	0.639760677997565	-0.446661113190455	756	2	0.0689655172413793	29	10285	567,2066	B2M,ERBB4
R-HSA-177929	Signaling by EGFR	0.648801003163406	-0.432629229999322	364	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-3700989	Transcriptional Regulation by TP53	0.651872079545823	-0.427906933320245	367	1	0.0344827586206897	29	10285	79370	BCL2L14
R-HSA-5663202	Diseases of signal transduction	0.653905041324849	-0.424793134818002	369	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-2454202	Fc epsilon receptor (FCERI) signaling	0.656933006953939	-0.420173233803266	372	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-983169	Class I MHC mediated antigen processing & presentation	0.657936632771975	-0.418646655072384	373	1	0.0344827586206897	29	10285	567	B2M
R-HSA-187037	NGF signalling via TRKA from the plasma membrane	0.671693195394336	-0.397953597184428	387	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-556833	Metabolism of lipids and lipoproteins	0.680077837394397	-0.385548020606338	813	2	0.0689655172413793	29	10285	5730,873	PTGDS,CBR1
R-HSA-194315	Signaling by Rho GTPases	0.707257095842477	-0.346361035846228	426	1	0.0344827586206897	29	10285	94274	PPP1R14A
R-HSA-212436	Generic Transcription Pathway	0.713749870656851	-0.337222699228254	865	2	0.0689655172413793	29	10285	79370,147929	BCL2L14,ZNF565
R-HSA-881907	Gastrin-CREB signalling pathway via PKC and MAPK	0.721567610901836	-0.326329196354953	443	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-1430728	Metabolism	0.758296715289732	-0.2766805249611	2158	5	0.172413793103448	29	10285	6158,6135,4718,873,5730	RPL28,RPL11,NDUFC2,CBR1,PTGDS
R-HSA-162582	Signal Transduction	0.759780071770228	-0.274726266829715	2547	6	0.206896551724138	29	10285	9765,4974,2066,3908,94274,6696	ZFYVE16,OMG,ERBB4,LAMA2,PPP1R14A,SPP1
R-HSA-74160	Gene Expression	0.781052838098019	-0.24711247701603	1821	4	0.137931034482759	29	10285	79370,6158,6135,147929	BCL2L14,RPL28,RPL11,ZNF565
R-HSA-449147	Signaling by Interleukins	0.781628380664472	-0.246375867929588	525	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-597592	Post-translational protein modification	0.804052021601874	-0.218091308411433	1034	2	0.0689655172413793	29	10285	1603,288	DAD1,ANK3
R-HSA-372790	Signaling by GPCR	0.980183897622769	-0.0200150742862196	1299	1	0.0344827586206897	29	10285	2066	ERBB4
R-HSA-422356	Regulation of insulin secretion	0.999999999959954	-4.00458004116405e-11	80	0	0	29	10285
R-HSA-5624138	Trafficking of myristoylated proteins to the cilium	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5676934	Protein repair	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-1482798	Acyl chain remodeling of CL	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-193144	Estrogen biosynthesis	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-6793080	rRNA modification in the mitochondrion	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-6806942	MET Receptor Activation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-176417	Phosphorylation of Emi1	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-77288	mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-193670	p75NTR negatively regulates cell cycle via SC1	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-442717	CREB phosphorylation through the activation of CaMKK	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-193993	Mineralocorticoid biosynthesis	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-388479	Vasopressin-like receptors	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-3323169	Defects in biotin (Btn) metabolism	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-6787639	GDP-fucose biosynthesis	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-3134973	LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-173623	Classical antibody-mediated complement activation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-205025	NADE modulates death signalling	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5339717	Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-2142712	Synthesis of 12-eicosatetraenoic acid derivatives	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-6782861	Synthesis of wybutosine at G37 of tRNA(Phe)	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-2142700	Synthesis of Lipoxins (LX)	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-2187335	The retinoid cycle in cones (daylight vision)	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-177135	Conjugation of benzoate with glycine	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5674499	Negative feedback regulation of MAPK pathway	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-189483	Heme degradation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-1237112	Methionine salvage pathway	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-8851907	MET activates PI3K/AKT signaling	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-166662	Lectin pathway of complement activation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-68616	Assembly of the ORC complex at the origin of replication	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-1566977	Fibronectin matrix formation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-3304356	SMAD2/3 Phosphorylation Motif Mutants in Cancer	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-8857538	PTK6 promotes HIF1A stabilization	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-428808	Na+-dependent glucose transporters	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-211916	Vitamins	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-390247	Beta-oxidation of very long chain fatty acids	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5660668	CLEC7A/inflammasome pathway	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-6799990	Metal sequestration by antimicrobial proteins	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-187015	Activation of TRKA receptors	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5579029	Metabolic disorders of biological oxidation enzymes	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-190370	FGFR1b ligand binding and activation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-3000484	Scavenging by Class F Receptors	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-444257	RSK activation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-3371599	Defective HLCS causes multiple carboxylase deficiency	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5693548	Sensing of DNA Double Strand Breaks	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5626978	TNFR1-mediated ceramide production	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-2142770	Synthesis of 15-eicosatetraenoic acid derivatives	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-3065679	SUMO is proteolytically processed	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-947581	Molybdenum cofactor biosynthesis	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-446199	Synthesis of Dolichyl-phosphate	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-6798163	Choline catabolism	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5368598	Negative regulation of TCF-dependent signaling by DVL-interacting proteins	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-8849470	PTK6 Regulates Cell Cycle	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-111957	Cam-PDE 1 activation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-500753	Pyrimidine biosynthesis	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5690714	CD22 mediated BCR regulation	0.999999999967717	-3.22829357300907e-11	6	0	0	29	10285
R-HSA-5689603	UCH proteinases	0.999999999968328	-3.16716422706055e-11	105	0	0	29	10285
R-HSA-391251	Protein folding	0.999999999968328	-3.16716422706055e-11	105	0	0	29	10285
R-HSA-5693532	DNA Double-Strand Break Repair	0.999999999968336	-3.16644361969637e-11	167	0	0	29	10285
R-HSA-2029480	Fcgamma receptor (FCGR) dependent phagocytosis	0.999999999969189	-3.08113888667938e-11	86	0	0	29	10285
R-HSA-69002	DNA Replication Pre-Initiation	0.999999999969189	-3.08113888667938e-11	86	0	0	29	10285
R-HSA-5632684	Hedgehog 'on' state	0.999999999969189	-3.08113888667938e-11	86	0	0	29	10285
R-HSA-68874	M/G1 Transition	0.999999999969189	-3.08113888667938e-11	86	0	0	29	10285
R-HSA-5368287	Mitochondrial translation	0.999999999969246	-3.07542035961707e-11	94	0	0	29	10285
R-HSA-3214815	HDACs deacetylate histones	0.999999999969246	-3.07542035961707e-11	94	0	0	29	10285
R-HSA-2122947	NOTCH1 Intracellular Domain Regulates Transcription	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-168643	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-392451	G beta:gamma signalling through PI3Kgamma	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-73762	RNA Polymerase I Transcription Initiation	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-4570464	SUMOylation of RNA binding proteins	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-380108	Chemokine receptors bind chemokines	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-112040	G-protein mediated events	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-1368108	BMAL1:CLOCK,NPAS2 activates circadian gene expression	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-418597	G alpha (z) signalling events	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-3928665	EPH-ephrin mediated repulsion of cells	0.999999999971101	-2.88993934211647e-11	48	0	0	29	10285
R-HSA-446107	Type I hemidesmosome assembly	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-71288	Creatine metabolism	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-71182	Phenylalanine and tyrosine catabolism	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-77588	SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5602498	MyD88 deficiency (TLR2/4)	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-1059683	Interleukin-6 signaling	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-937039	IRAK1 recruits IKK complex	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5661231	Metallothioneins bind metals	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-1980150	Signaling by NOTCH4	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5603041	IRAK4 deficiency (TLR2/4)	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-3371378	Regulation by c-FLIP	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-2022923	Dermatan sulfate biosynthesis	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-8851805	MET activates RAS signaling	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-196780	Biotin transport and metabolism	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-1855183	Synthesis of IP2, IP, and Ins in the cytosol	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-381183	ATF6 (ATF6-alpha) activates chaperone genes	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-418889	Ligand-independent caspase activation via DCC	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-2470946	Cohesin Loading onto Chromatin	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-73614	Pyrimidine salvage reactions	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-1839122	Signaling by activated point mutants of FGFR1	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-200425	Import of palmitoyl-CoA into the mitochondrial matrix	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-975144	IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-2514853	Condensation of Prometaphase Chromosomes	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-351906	Apoptotic cleavage of cell adhesion  proteins	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5218900	CASP8 activity is inhibited	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-1980148	Signaling by NOTCH3	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5655291	Signaling by FGFR4 in disease	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-2485179	Activation of the phototransduction cascade	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5685939	HDR through MMEJ (alt-NHEJ)	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-211999	CYP2E1 reactions	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5660526	Response to metal ions	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-69416	Dimerization of procaspase-8	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-8875555	MET activates RAP1 and RAC1	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-174414	Processive synthesis on the C-strand of the telomere	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-174495	Synthesis And Processing Of GAG, GAGPOL Polyproteins	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-75072	mRNA Editing	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-376172	DSCAM interactions	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-189451	Heme biosynthesis	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-380320	Recruitment of NuMA to mitotic centrosomes	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-193048	Androgen biosynthesis	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-174490	Membrane binding and targetting of GAG proteins	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-159854	Gamma-carboxylation, transport, and amino-terminal cleavage of proteins	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-5625970	RHO GTPases activate KTN1	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-3296469	Defects in cobalamin (B12) metabolism	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-68689	CDC6 association with the ORC:origin complex	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-549127	Organic cation transport	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-629594	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	0.999999999971455	-2.85447872074827e-11	11	0	0	29	10285
R-HSA-901042	Calnexin/calreticulin cycle	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-8849471	PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-5693554	Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-76066	RNA Polymerase III Transcription Initiation From Type 2 Promoter	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-167160	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-2173788	Downregulation of TGF-beta receptor signaling	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-77387	Insulin receptor recycling	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-77075	RNA Pol II CTD phosphorylation and interaction with CE	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-400685	Sema4D in semaphorin signaling	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-114508	Effects of PIP2 hydrolysis	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-1482788	Acyl chain remodelling of PC	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-977606	Regulation of Complement cascade	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-380994	ATF4 activates genes	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-180024	DARPP-32 events	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-5654716	Downstream signaling of activated FGFR4	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-6783589	Interleukin-6 family signaling	0.999999999971973	-2.80274029328147e-11	27	0	0	29	10285
R-HSA-6788656	Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism	0.999999999974415	-2.55847736577618e-11	44	0	0	29	10285
R-HSA-975634	Retinoid metabolism and transport	0.999999999974415	-2.55847736577618e-11	44	0	0	29	10285
R-HSA-159231	Transport of Mature mRNA Derived from an Intronless Transcript	0.999999999974415	-2.55847736577618e-11	44	0	0	29	10285
R-HSA-1296072	Voltage gated Potassium channels	0.999999999974415	-2.55847736577618e-11	44	0	0	29	10285
R-HSA-1660661	Sphingolipid de novo biosynthesis	0.999999999974415	-2.55847736577618e-11	44	0	0	29	10285
R-HSA-109606	Intrinsic Pathway for Apoptosis	0.999999999974415	-2.55847736577618e-11	44	0	0	29	10285
R-HSA-5668914	Diseases of metabolism	0.999999999974415	-2.55847736577618e-11	44	0	0	29	10285
R-HSA-6803157	Antimicrobial peptides	0.999999999975466	-2.45340014898985e-11	97	0	0	29	10285
R-HSA-168138	Toll Like Receptor 9 (TLR9) Cascade	0.999999999975466	-2.45340014898985e-11	97	0	0	29	10285
R-HSA-15869	Metabolism of nucleotides	0.999999999975466	-2.45340014898985e-11	97	0	0	29	10285
R-HSA-194840	Rho GTPase cycle	0.999999999975555	-2.44449504094596e-11	142	0	0	29	10285
R-HSA-5576891	Cardiac conduction	0.999999999975555	-2.44449504094596e-11	142	0	0	29	10285
R-HSA-168928	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways	0.999999999975806	-2.41942309758682e-11	84	0	0	29	10285
R-HSA-168176	Toll Like Receptor 5 (TLR5) Cascade	0.999999999975806	-2.41942309758682e-11	84	0	0	29	10285
R-HSA-168142	Toll Like Receptor 10 (TLR10) Cascade	0.999999999975806	-2.41942309758682e-11	84	0	0	29	10285
R-HSA-975871	MyD88 cascade initiated on plasma membrane	0.999999999975806	-2.41942309758682e-11	84	0	0	29	10285
R-HSA-1855204	Synthesis of IP3 and IP4 in the cytosol	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-76071	RNA Polymerase III Transcription Initiation From Type 3 Promoter	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-1266695	Interleukin-7 signaling	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-174800	Chylomicron-mediated lipid transport	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-190828	Gap junction trafficking	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-76061	RNA Polymerase III Transcription Initiation From Type 1 Promoter	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-6811436	COPI-independent Golgi-to-ER retrograde traffic	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-354192	Integrin alphaIIb beta3 signaling	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-400042	Adrenaline,noradrenaline inhibits insulin secretion	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-5621480	Dectin-2 family	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-111933	Calmodulin induced events	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-264876	Insulin processing	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-1483191	Synthesis of PC	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-437239	Recycling pathway of L1	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-6803529	FGFR2 alternative splicing	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-917729	Endosomal Sorting Complex Required For Transport (ESCRT)	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-380972	Energy dependent regulation of mTOR by LKB1-AMPK	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-111997	CaM pathway	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-5357769	Caspase activation via extrinsic apoptotic signalling pathway	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-211976	Endogenous sterols	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-70268	Pyruvate metabolism	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-1368082	RORA activates gene expression	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-75876	Synthesis of very long-chain fatty acyl-CoAs	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-2022854	Keratan sulfate biosynthesis	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-5576893	Phase 2 - plateau phase	0.99999999997605	-2.39495260599535e-11	28	0	0	29	10285
R-HSA-936837	Ion transport by P-type ATPases	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-2894858	Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-2644603	Signaling by NOTCH1 in Cancer	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-5362768	Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-2644602	Signaling by NOTCH1 PEST Domain Mutants in Cancer	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-2894862	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-2644606	Constitutive Signaling by NOTCH1 PEST Domain Mutants	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-381070	IRE1alpha activates chaperones	0.999999999976511	-2.34885326075684e-11	58	0	0	29	10285
R-HSA-176408	Regulation of APC/C activators between G1/S and early anaphase	0.999999999976681	-2.33192365378787e-11	81	0	0	29	10285
R-HSA-70326	Glucose metabolism	0.999999999976681	-2.33192365378787e-11	81	0	0	29	10285
R-HSA-937041	IKK complex recruitment mediated by RIP1	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-193368	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-416572	Sema4D induced cell migration and growth-cone collapse	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-191273	Cholesterol biosynthesis	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-210500	Glutamate Neurotransmitter Release Cycle	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-156588	Glucuronidation	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-110373	Resolution of AP sites via the multiple-nucleotide patch replacement pathway	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-171052	LDL-mediated lipid transport	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-5602358	Diseases associated with the TLR signaling cascade	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-70895	Branched-chain amino acid catabolism	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-5260271	Diseases of Immune System	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-174417	Telomere C-strand (Lagging Strand) Synthesis	0.999999999977191	-2.28088742223545e-11	24	0	0	29	10285
R-HSA-379724	tRNA Aminoacylation	0.999999999977197	-2.28025509717472e-11	45	0	0	29	10285
R-HSA-159234	Transport of Mature mRNAs Derived from Intronless Transcripts	0.999999999977197	-2.28025509717472e-11	45	0	0	29	10285
R-HSA-166658	Complement cascade	0.999999999977197	-2.28025509717472e-11	45	0	0	29	10285
R-HSA-6811438	Intra-Golgi traffic	0.999999999977197	-2.28025509717472e-11	45	0	0	29	10285
R-HSA-8854214	TBC/RABGAPs	0.999999999977197	-2.28025509717472e-11	45	0	0	29	10285
R-HSA-2151201	Transcriptional activation of mitochondrial biogenesis	0.999999999977197	-2.28025509717472e-11	45	0	0	29	10285
R-HSA-5668541	TNFR2 non-canonical NF-kB pathway	0.99999999997755	-2.24497083291907e-11	104	0	0	29	10285
R-HSA-2672351	Stimuli-sensing channels	0.99999999997755	-2.24497083291907e-11	104	0	0	29	10285
R-HSA-3108232	SUMO E3 ligases SUMOylate target proteins	0.99999999997755	-2.24497083291907e-11	104	0	0	29	10285
R-HSA-4791275	Signaling by WNT in cancer	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-6802948	Signaling by high-kinase activity BRAF mutants	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-933541	TRAF6 mediated IRF7 activation	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-113418	Formation of the Early Elongation Complex	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-2514859	Inactivation, recovery and regulation of the phototransduction cascade	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-159230	Transport of the SLBP Dependant Mature mRNA	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-6804757	Regulation of TP53 Degradation	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-5693537	Resolution of D-Loop Structures	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-3301854	Nuclear Pore Complex (NPC) Disassembly	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-167158	Formation of the HIV-1 Early Elongation Complex	0.999999999977575	-2.24253465403057e-11	35	0	0	29	10285
R-HSA-1630316	Glycosaminoglycan metabolism	0.99999999997769	-2.23103454900753e-11	124	0	0	29	10285
R-HSA-1989781	PPARA activates gene expression	0.99999999997769	-2.23103454900753e-11	124	0	0	29	10285
R-HSA-69239	Synthesis of DNA	0.999999999978165	-2.18349496911019e-11	101	0	0	29	10285
R-HSA-5607764	CLEC7A (Dectin-1) signaling	0.999999999978165	-2.18349496911019e-11	101	0	0	29	10285
R-HSA-2187338	Visual phototransduction	0.999999999978165	-2.18349496911019e-11	101	0	0	29	10285
R-HSA-5610787	Hedgehog 'off' state	0.999999999978165	-2.18349496911019e-11	101	0	0	29	10285
R-HSA-168188	Toll Like Receptor TLR6:TLR2 Cascade	0.999999999978241	-2.17585763306296e-11	95	0	0	29	10285
R-HSA-181438	Toll Like Receptor 2 (TLR2) Cascade	0.999999999978241	-2.17585763306296e-11	95	0	0	29	10285
R-HSA-2682334	EPH-Ephrin signaling	0.999999999978241	-2.17585763306296e-11	95	0	0	29	10285
R-HSA-69473	G2/M DNA damage checkpoint	0.999999999978241	-2.17585763306296e-11	95	0	0	29	10285
R-HSA-166058	MyD88:Mal cascade initiated on plasma membrane	0.999999999978241	-2.17585763306296e-11	95	0	0	29	10285
R-HSA-168179	Toll Like Receptor TLR1:TLR2 Cascade	0.999999999978241	-2.17585763306296e-11	95	0	0	29	10285
R-HSA-73933	Resolution of Abasic Sites (AP sites)	0.999999999978252	-2.17481039943806e-11	37	0	0	29	10285
R-HSA-5083635	Defective B3GALTL causes Peters-plus syndrome (PpS)	0.999999999978252	-2.17481039943806e-11	37	0	0	29	10285
R-HSA-5689896	Ovarian tumor domain proteases	0.999999999978252	-2.17481039943806e-11	37	0	0	29	10285
R-HSA-73884	Base Excision Repair	0.999999999978252	-2.17481039943806e-11	37	0	0	29	10285
R-HSA-438064	Post NMDA receptor activation events	0.999999999978252	-2.17481039943806e-11	37	0	0	29	10285
R-HSA-176187	Activation of ATR in response to replication stress	0.999999999978252	-2.17481039943806e-11	37	0	0	29	10285
R-HSA-419037	NCAM1 interactions	0.999999999978252	-2.17481039943806e-11	37	0	0	29	10285
R-HSA-5658442	Regulation of RAS by GAPs	0.999999999978285	-2.17145689875186e-11	70	0	0	29	10285
R-HSA-1650814	Collagen biosynthesis and modifying enzymes	0.999999999978285	-2.17145689875186e-11	70	0	0	29	10285
R-HSA-3371453	Regulation of HSF1-mediated heat shock response	0.999999999978285	-2.17145689875186e-11	70	0	0	29	10285
R-HSA-75109	Triglyceride Biosynthesis	0.99999999997837	-2.16296291149264e-11	82	0	0	29	10285
R-HSA-6811434	COPI-dependent Golgi-to-ER retrograde traffic	0.99999999997837	-2.16296291149264e-11	82	0	0	29	10285
R-HSA-380270	Recruitment of mitotic centrosome proteins and complexes	0.99999999997837	-2.16296291149264e-11	82	0	0	29	10285
R-HSA-157579	Telomere Maintenance	0.99999999997837	-2.16296291149264e-11	82	0	0	29	10285
R-HSA-380287	Centrosome maturation	0.99999999997837	-2.16296291149264e-11	82	0	0	29	10285
R-HSA-5628897	TP53 Regulates Metabolic Genes	0.99999999997837	-2.16296291149264e-11	82	0	0	29	10285
R-HSA-73856	RNA Polymerase II Transcription Termination	0.999999999978514	-2.14863689559935e-11	71	0	0	29	10285
R-HSA-109688	Cleavage of Growing Transcript in the Termination Region	0.999999999978514	-2.14863689559935e-11	71	0	0	29	10285
R-HSA-400253	Circadian Clock	0.999999999978514	-2.14863689559935e-11	71	0	0	29	10285
R-HSA-6809371	Formation of the cornified envelope	0.999999999978514	-2.14863689559935e-11	71	0	0	29	10285
R-HSA-69656	Cyclin A:Cdk2-associated events at S phase entry	0.999999999978514	-2.14863689559935e-11	71	0	0	29	10285
R-HSA-3560782	Diseases associated with glycosaminoglycan metabolism	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-1971475	A tetrasaccharide linker sequence is required for GAG synthesis	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-975298	Ligand-gated ion channel transport	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-210991	Basigin interactions	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-73848	Pyrimidine metabolism	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-2029485	Role of phospholipids in phagocytosis	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-912694	Regulation of IFNA signaling	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-975576	N-glycan antennae elongation in the medial/trans-Golgi	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-3238698	WNT ligand biogenesis and trafficking	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-5357956	TNFR1-induced NFkappaB signaling pathway	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-389960	Formation of tubulin folding intermediates by CCT/TriC	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-379716	Cytosolic tRNA aminoacylation	0.999999999978889	-2.11109235098497e-11	26	0	0	29	10285
R-HSA-5620922	BBSome-mediated cargo-targeting to cilium	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-73980	RNA Polymerase III Transcription Termination	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-379726	Mitochondrial tRNA aminoacylation	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-5654695	PI-3K cascade:FGFR2	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-2173795	Downregulation of SMAD2/3:SMAD4 transcriptional activity	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-389977	Post-chaperonin tubulin folding pathway	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-5654699	SHC-mediated cascade:FGFR2	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-400508	Incretin synthesis, secretion, and inactivation	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-392170	ADP signalling through P2Y purinoceptor 12	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-212676	Dopamine Neurotransmitter Release Cycle	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-428930	Thromboxane signalling through TP receptor	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-174048	APC/C:Cdc20 mediated degradation of Cyclin B	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-5627123	RHO GTPases activate PAKs	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-112409	RAF-independent MAPK1/3 activation	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-2453902	The canonical retinoid cycle in rods (twilight vision)	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-5205685	Pink/Parkin Mediated Mitophagy	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-5654693	FRS-mediated FGFR1 signaling	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-5365859	RA biosynthesis pathway	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-8863678	Neurodegenerative Diseases	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-8862803	Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-5205647	Mitophagy	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-8855121	VLDL interactions	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-3371571	HSF1-dependent transactivation	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-389948	PD-1 signaling	0.999999999979232	-2.07679109715576e-11	23	0	0	29	10285
R-HSA-3214847	HATs acetylate histones	0.999999999979317	-2.06832685292496e-11	143	0	0	29	10285
R-HSA-453279	Mitotic G1-G1/S phases	0.999999999979317	-2.06832685292496e-11	143	0	0	29	10285
R-HSA-1500620	Meiosis	0.999999999979819	-2.01808827484107e-11	121	0	0	29	10285
R-HSA-5625886	Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	0.999999999980057	-1.99435060390428e-11	67	0	0	29	10285
R-HSA-5358346	Hedgehog ligand biogenesis	0.999999999980057	-1.99435060390428e-11	67	0	0	29	10285
R-HSA-1632852	Macroautophagy	0.999999999980057	-1.99435060390428e-11	67	0	0	29	10285
R-HSA-4608870	Asymmetric localization of PCP proteins	0.999999999980057	-1.99435060390428e-11	67	0	0	29	10285
R-HSA-1234176	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	0.999999999980057	-1.99435060390428e-11	67	0	0	29	10285
R-HSA-69615	G1/S DNA Damage Checkpoints	0.999999999980057	-1.99435060390428e-11	67	0	0	29	10285
R-HSA-5687868	Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-114294	Activation, translocation and oligomerization of BAX	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-1614603	Cysteine formation from homocysteine	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-211728	Regulation of PAK-2p34 activity by PS-GAP/RHG10	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-168277	Influenza Virus Induced Apoptosis	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-164939	Nef mediated downregulation of CD28 cell surface expression	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-211994	Sterols are 12-hydroxylated by CYP8B1	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-6804754	Regulation of TP53 Expression	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5638302	Signaling by Overexpressed Wild-Type EGFR in Cancer	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3828062	Glycogen storage disease type 0 (muscle GYS1)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-75064	mRNA Editing: A to I Conversion	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-165160	PDE3B signalling	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-432030	Transport of glycerol from adipocytes to the liver by Aquaporins	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5602636	IKBKB deficiency causes SCID	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3359467	Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-198765	Signalling to ERK5	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-1483101	Synthesis of PS	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-73930	Abasic sugar-phosphate removal via the single-nucleotide replacement pathway	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-480985	Synthesis of dolichyl-phosphate-glucose	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5652227	Fructose biosynthesis	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-156582	Acetylation	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-75896	Plasmalogen biosynthesis	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-141424	Amplification of signal from the kinetochores	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5683177	Defective ABCC8 can cause hypoglycemias and hyperglycemias	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3642279	TGFBR2 MSI Frameshift Mutants in Cancer	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-141333	Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5579031	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3359473	Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-380612	Metabolism of serotonin	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3359485	Defective CD320 causes methylmalonic aciduria	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-111452	Activation and oligomerization of BAK protein	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-844623	The IPAF inflammasome	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-163754	Insulin effects increased synthesis of Xylulose-5-Phosphate	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5602566	TICAM1 deficiency - HSE	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-351143	Agmatine biosynthesis	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-168315	Inhibition of Host mRNA Processing and RNA Silencing	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-75102	C6 deamination of adenosine	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-888568	GABA synthesis	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5357609	Glycogen storage disease type II (GAA)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-111995	phospho-PLA2 pathway	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-205017	NFG and proNGF binds to p75NTR	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-1483152	Hydrolysis of LPE	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5638303	Inhibition of Signaling by Overexpressed EGFR	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-1299361	TWIK-related alkaline pH activated K+ channel (TALK)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-203754	NOSIP mediated eNOS trafficking	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-190872	Transport of connexons to the plasma membrane	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-211736	Stimulation of the cell death response by PAK-2p34	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-68881	Mitotic Metaphase/Anaphase Transition	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-141444	Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-451307	Activation of Na-permeable Kainate Receptors	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-1299316	TWIK-releated acid-sensitive K+ channel (TASK)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-8942233	Intestinal infectious diseases	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3858516	Glycogen storage disease type 0 (liver GYS2)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-177162	Conjugation of phenylacetate with glutamine	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-71737	Pyrophosphate hydrolysis	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5545619	XAV939 inhibits tankyrase, stabilizing AXIN	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-8854521	Interaction between PHLDA1 and AURKA	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-70688	Proline catabolism	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5688354	Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-168316	Assembly of Viral Components at the Budding Site	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-5619107	Defective TRP may confer susceptibility towards thyroid papillary carcinoma (TPC)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3814836	Glycogen storage disease type XV (GYG1)	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-428559	Proton-coupled neutral amino acid transporters	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3359475	Defective MMAA causes methylmalonic aciduria type cblA	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3359469	Defective MTR causes methylmalonic aciduria and homocystinuria type cblG	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-168275	Entry of Influenza Virion into Host Cell via Endocytosis	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-141334	PAOs oxidise polyamines to amines	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-3359478	Defective MUT causes methylmalonic aciduria mut type	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-192905	vRNP Assembly	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-916853	Degradation of GABA	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-8849175	Threonine catabolism	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-111457	Release of apoptotic factors from the mitochondria	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-168268	Virus Assembly and Release	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-77042	Formation of editosomes by ADAR proteins	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-187042	TRKA activation by NGF	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-166020	Transfer of LPS from LBP carrier to CD14	0.999999999980152	-1.98479894849337e-11	2	0	0	29	10285
R-HSA-1169408	ISG15 antiviral mechanism	0.999999999980197	-1.98031018971184e-11	76	0	0	29	10285
R-HSA-427389	ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	0.999999999980197	-1.98031018971184e-11	76	0	0	29	10285
R-HSA-176409	APC/C:Cdc20 mediated degradation of mitotic proteins	0.999999999980197	-1.98031018971184e-11	76	0	0	29	10285
R-HSA-204998	Cell death signalling via NRAGE, NRIF and NADE	0.999999999980197	-1.98031018971184e-11	76	0	0	29	10285
R-HSA-5693606	DNA Double Strand Break Response	0.999999999980197	-1.98031018971184e-11	76	0	0	29	10285
R-HSA-5619115	Disorders of transmembrane transporters	0.999999999980197	-1.98031018971184e-11	76	0	0	29	10285
R-HSA-1169410	Antiviral mechanism by IFN-stimulated genes	0.999999999980197	-1.98031018971184e-11	76	0	0	29	10285
R-HSA-5693607	Processing of DNA double-strand break ends	0.999999999980609	-1.93911528326585e-11	98	0	0	29	10285
R-HSA-202424	Downstream TCR signaling	0.999999999980609	-1.93911528326585e-11	98	0	0	29	10285
R-HSA-418594	G alpha (i) signalling events	0.999999999980847	-1.91534072671069e-11	242	0	0	29	10285
R-HSA-983231	Factors involved in megakaryocyte development and platelet production	0.999999999980949	-1.90513974949885e-11	156	0	0	29	10285
R-HSA-3595177	Defective CHSY1 causes TPBS	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-448706	Interleukin-1 processing	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-1912399	Pre-NOTCH Processing in the Endoplasmic Reticulum	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3656244	Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-6814848	Glycerophospholipid catabolism	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-171319	Telomere Extension By Telomerase	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-210744	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-5649702	APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-111471	Apoptotic factor-mediated response	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-174577	Activation of C3 and C5	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-2993913	Clearance of Nuclear Envelope Membranes from Chromatin	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-110362	POLB-Dependent Long Patch Base Excision Repair	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3304349	Loss of Function of SMAD2/3 in Cancer	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-5603029	IkBA variant leads to EDA-ID	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-190371	FGFR3b ligand binding and activation	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-435368	Zinc efflux and compartmentalization by the SLC30 family	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-426496	Post-transcriptional silencing by small RNAs	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-442720	CREB phosphorylation through the activation of Adenylate Cyclase	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-447043	Neurofascin interactions	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3595172	Defective CHST3 causes SEDCJD	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-433692	Proton-coupled monocarboxylate transport	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-164843	2-LTR circle formation	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-5576894	Phase 1 - inactivation of fast Na+ channels	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-429593	Inositol transporters	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3315487	SMAD2/3 MH2 Domain Mutants in Cancer	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3595174	Defective CHST14 causes EDS, musculocontractural type	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-2660826	Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-2660825	Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-426117	Cation-coupled Chloride cotransporters	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-174362	Transport and synthesis of PAPS	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-420597	Nectin/Necl  trans heterodimerization	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-2980767	Activation of NIMA Kinases NEK9, NEK6, NEK7	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-5619102	SLC transporter disorders	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3656243	Defective ST3GAL3 causes MCT12 and EIEE15	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-447038	NrCAM interactions	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3065678	SUMO is transferred from E1 to E2 (UBE2I, UBC9)	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-2393930	Phosphate bond hydrolysis by NUDT proteins	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-196843	Vitamin B2 (riboflavin) metabolism	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-162791	Attachment of GPI anchor to uPAR	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-163767	PP2A-mediated dephosphorylation of key metabolic factors	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-629587	Highly sodium permeable acetylcholine nicotinic receptors	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-73943	Reversal of alkylation damage by DNA dioxygenases	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-3656225	Defective CHST6 causes MCDC1	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-5652084	Fructose metabolism	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-83936	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-196791	Vitamin D (calciferol) metabolism	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-182218	Nef Mediated CD8 Down-regulation	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-199920	CREB phosphorylation	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-75158	TRAIL  signaling	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-4411364	Binding of TCF/LEF:CTNNB1 to target gene promoters	0.999999999981096	-1.89042341816936e-11	7	0	0	29	10285
R-HSA-5610785	GLI3 is processed to GLI3R by the proteasome	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-5610780	Degradation of GLI1 by the proteasome	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-72702	Ribosomal scanning and start codon recognition	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-4086398	Ca2+ pathway	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-5607761	Dectin-1 mediated noncanonical NF-kB signaling	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-5610783	Degradation of GLI2 by the proteasome	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-187577	SCF(Skp2)-mediated degradation of p27/p21	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-2029482	Regulation of actin dynamics for phagocytic cup formation	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-8852276	The role of GTSE1 in G2/M progression after G2 checkpoint	0.999999999981247	-1.87533849634944e-11	61	0	0	29	10285
R-HSA-1483257	Phospholipid metabolism	0.999999999981413	-1.85874179800956e-11	207	0	0	29	10285
R-HSA-5654738	Signaling by FGFR2	0.999999999981898	-1.81016777295647e-11	75	0	0	29	10285
R-HSA-159236	Transport of Mature mRNA derived from an Intron-Containing Transcript	0.999999999981898	-1.81016777295647e-11	75	0	0	29	10285
R-HSA-8854518	AURKA Activation by TPX2	0.999999999981898	-1.81016777295647e-11	75	0	0	29	10285
R-HSA-5693565	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	0.999999999981898	-1.81016777295647e-11	75	0	0	29	10285
R-HSA-446193	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	0.999999999982426	-1.75742883981685e-11	78	0	0	29	10285
R-HSA-3108214	SUMOylation of DNA damage response and repair proteins	0.999999999982426	-1.75742883981685e-11	78	0	0	29	10285
R-HSA-4641258	Degradation of DVL	0.999999999982649	-1.73510013013564e-11	59	0	0	29	10285
R-HSA-3906995	Diseases associated with O-glycosylation of proteins	0.999999999982649	-1.73510013013564e-11	59	0	0	29	10285
R-HSA-70171	Glycolysis	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-376176	Signaling by Robo receptor	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-456926	Thrombin signalling through proteinase activated receptors (PARs)	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-1592389	Activation of Matrix Metalloproteinases	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-168274	Export of Viral Ribonucleoproteins from Nucleus	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-399721	Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-196071	Metabolism of steroid hormones	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-2559585	Oncogene Induced Senescence	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-451326	Activation of Kainate Receptors upon glutamate binding	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-73863	RNA Polymerase I Transcription Termination	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-70263	Gluconeogenesis	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-4641262	Disassembly of the destruction complex and recruitment of AXIN to the membrane	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-69190	DNA strand elongation	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-399719	Trafficking of AMPA receptors	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-68962	Activation of the pre-replicative complex	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-168638	NOD1/2 Signaling Pathway	0.999999999983263	-1.6736839970056e-11	32	0	0	29	10285
R-HSA-112315	Transmission across Chemical Synapses	0.99999999998327	-1.67301484668812e-11	217	0	0	29	10285
R-HSA-5621481	C-type lectin receptors (CLRs)	0.999999999983465	-1.65346614687058e-11	144	0	0	29	10285
R-HSA-5654706	FRS-mediated FGFR3 signaling	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-3000170	Syndecan interactions	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-5637815	Signaling by Ligand-Responsive EGFR Variants in Cancer	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-5654720	PI-3K cascade:FGFR4	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-6788467	IL-6-type cytokine receptor ligand interactions	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-450302	activated TAK1 mediates p38 MAPK activation	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-194223	HDL-mediated lipid transport	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-163560	Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-141405	Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-1643713	Signaling by EGFR in Cancer	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-5654719	SHC-mediated cascade:FGFR4	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-69186	Lagging Strand Synthesis	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-418217	G beta:gamma signalling through PLC beta	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-6804760	Regulation of TP53 Activity through Methylation	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-8876384	Listeria monocytogenes entry into host cells	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-190241	FGFR2 ligand binding and activation	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-381771	Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-1236382	Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-141430	Inactivation of APC/C via direct inhibition of the APC/C complex	0.999999999984362	-1.56384316382609e-11	20	0	0	29	10285
R-HSA-1221632	Meiotic synapsis	0.999999999984425	-1.55754027089594e-11	79	0	0	29	10285
R-HSA-3214858	RMTs methylate histone arginines	0.999999999984425	-1.55754027089594e-11	79	0	0	29	10285
R-HSA-1483255	PI Metabolism	0.999999999984425	-1.55754027089594e-11	79	0	0	29	10285
R-HSA-2559586	DNA Damage/Telomere Stress Induced Senescence	0.999999999984425	-1.55754027089594e-11	79	0	0	29	10285
R-HSA-2871837	FCERI mediated NF-kB activation	0.999999999984425	-1.55754027089594e-11	79	0	0	29	10285
R-HSA-109704	PI3K Cascade	0.999999999984425	-1.55754027089594e-11	79	0	0	29	10285
R-HSA-6781827	Transcription-Coupled Nucleotide Excision Repair (TC-NER)	0.999999999984425	-1.55754027089594e-11	79	0	0	29	10285
R-HSA-114516	Disinhibition of SNARE formation	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-77348	Beta oxidation of octanoyl-CoA to hexanoyl-CoA	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-1483226	Synthesis of PI	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-1306955	GRB7 events in ERBB2 signaling	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-1169092	Activation of RAS in B cells	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-380095	Tachykinin receptors bind tachykinins	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-5661270	Catabolism of glucuronate to xylulose-5-phosphate	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-111459	Activation of caspases through apoptosome-mediated cleavage	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-1614517	Sulfide oxidation to sulfate	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-426048	Arachidonate production from DAG	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8866376	Reelin signalling pathway	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-2161541	Abacavir metabolism	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-111932	CaMK IV-mediated phosphorylation of CREB	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-444209	Free fatty acid receptors	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-71032	Propionyl-CoA catabolism	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-210746	Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-3642278	Loss of Function of TGFBR2 in Cancer	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-2644607	Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-111461	Cytochrome c-mediated apoptotic response	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-203641	NOSTRIN mediated eNOS trafficking	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8849473	PTK6 Expression	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8853383	Lysosomal oligosaccharide catabolism	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-70350	Fructose catabolism	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-2161517	Abacavir transmembrane transport	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-391906	Leukotriene receptors	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-433137	Sodium-coupled sulphate, di- and tri-carboxylate transporters	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-71262	Carnitine synthesis	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-77310	Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-5250981	Toxicity of botulinum toxin type F (BoNT/F)	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-70370	Galactose catabolism	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-166187	Mitochondrial Uncoupling Proteins	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-75157	FasL/ CD95L signaling	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-74713	IRS activation	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-427652	Sodium-coupled phosphate cotransporters	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-111464	SMAC-mediated dissociation of IAP:caspase complexes	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-112307	Transmission across Electrical Synapses	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-196819	Vitamin B1 (thiamin) metabolism	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-390648	Muscarinic acetylcholine receptors	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-167827	The proton buffering model	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8866911	TFAP2 (AP-2) family regulates transcription of cell cycle factors	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8852405	Signaling by MST1	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-2142850	Hyaluronan biosynthesis and export	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8875513	MET interacts with TNS proteins	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-112303	Electric Transmission Across Gap Junctions	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8865999	MET activates PTPN11	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-77352	Beta oxidation of butanoyl-CoA to acetyl-CoA	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-68911	G2 Phase	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-2855086	Ficolins bind to repetitive carbohydrate structures on the target cell surface	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-389599	Alpha-oxidation of phytanate	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-390651	Dopamine receptors	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-1606341	IRF3 mediated activation of type 1 IFN	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-6785470	tRNA processing in the mitochondrion	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-209931	Serotonin and melatonin biosynthesis	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-2644605	FBXW7 Mutants and NOTCH1 in Cancer	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-111448	Activation of NOXA and translocation to mitochondria	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8849468	PTK6 Regulates Proteins Involved in RNA Processing	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-964739	N-glycan trimming and elongation in the cis-Golgi	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-3656535	TGFBR1 LBD Mutants in Cancer	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-3065676	SUMO is conjugated to E1 (UBA2:SAE1)	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8866423	VLDL biosynthesis	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-180689	APOBEC3G mediated resistance to HIV-1 infection	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-5683678	Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3)	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-446205	Synthesis of GDP-mannose	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-5662702	Melanin biosynthesis	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-8869496	TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-3000471	Scavenging by Class B Receptors	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-77346	Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-111469	SMAC-mediated apoptotic response	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-163358	PKA-mediated phosphorylation of key metabolic factors	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-77350	Beta oxidation of hexanoyl-CoA to butanoyl-CoA	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-111463	SMAC binds to IAPs	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-187024	NGF-independant TRKA activation	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-69478	G2/M DNA replication checkpoint	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-140834	Extrinsic Pathway of Fibrin Clot Formation	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-167826	The fatty acid cycling model	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-3645790	TGFBR2 Kinase Domain Mutants in Cancer	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-5250955	Toxicity of botulinum toxin type D (BoNT/D)	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-157881	Cyclin B2 mediated events	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-561048	Organic anion transport	0.999999999984584	-1.54160004615435e-11	5	0	0	29	10285
R-HSA-629602	Activation of Nicotinic Acetylcholine Receptors	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-5675482	Regulation of necroptotic cell death	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-190322	FGFR4 ligand binding and activation	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-1679131	Trafficking and processing of endosomal TLR	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-209952	Peptide hormone biosynthesis	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-209543	p75NTR recruits signalling complexes	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-4839748	AMER1 mutants destabilize the destruction complex	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-4839744	truncated APC mutants destabilize the destruction complex	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-428540	Activation of Rac	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-5358565	Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-69091	Polymerase switching	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-209560	NF-kB is activated and signals survival	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-418885	DCC mediated attractive signaling	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-1483213	Synthesis of PE	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-177504	Retrograde neurotrophin signalling	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-6804759	Regulation of TP53 Activity through Association with Co-factors	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-193775	Synthesis of bile acids and bile salts via 24-hydroxycholesterol	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-162658	Golgi Cisternae Pericentriolar Stack Reorganization	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-418359	Reduction of cytosolic Ca++ levels	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-419408	Lysosphingolipid and LPA receptors	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-5358606	Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-181431	Acetylcholine Binding And Downstream Events	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-2024101	CS/DS degradation	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-622327	Postsynaptic nicotinic acetylcholine receptors	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-174411	Polymerase switching on the C-strand of the telomere	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-204174	Regulation of pyruvate dehydrogenase (PDH) complex	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-1660516	Synthesis of PIPs at the early endosome membrane	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-877312	Regulation of IFNG signaling	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-174403	Glutathione synthesis and recycling	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-69166	Removal of the Flap Intermediate	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-5467337	APC truncation mutants have impaired AXIN binding	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-5467340	AXIN missense mutants destabilize the destruction complex	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-4839735	AXIN mutants destabilize the destruction complex, activating WNT signaling	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-5467348	Truncations of AMER1 destabilize the destruction complex	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-162594	Early Phase of HIV Life Cycle	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-69109	Leading Strand Synthesis	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-428790	Facilitative Na+-independent glucose transporters	0.99999999998462	-1.53800734739511e-11	14	0	0	29	10285
R-HSA-5250913	Positive epigenetic regulation of rRNA expression	0.999999999985079	-1.49211974841054e-11	108	0	0	29	10285
R-HSA-68875	Mitotic Prophase	0.999999999985143	-1.48571639747054e-11	141	0	0	29	10285
R-HSA-1592230	Mitochondrial biogenesis	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-189200	Hexose transport	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-69601	Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-114604	GPVI-mediated activation cascade	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-1638091	Heparan sulfate/heparin (HS-GAG) metabolism	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-69613	p53-Independent G1/S DNA damage checkpoint	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-69610	p53-Independent DNA Damage Response	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-169911	Regulation of Apoptosis	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-6781823	Formation of TC-NER Pre-Incision Complex	0.999999999985444	-1.45563974485431e-11	54	0	0	29	10285
R-HSA-389958	Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-3928663	EPHA-mediated growth cone collapse	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-2173796	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-165054	Rev-mediated nuclear export of HIV RNA	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-2173789	TGF-beta receptor signaling activates SMADs	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-1483166	Synthesis of PA	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-5656169	Termination of translesion DNA synthesis	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-159227	Transport of the SLBP independent Mature mRNA	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-390522	Striated Muscle Contraction	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-5654727	Negative regulation of FGFR2 signaling	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-1489509	DAG and IP3 signaling	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-5693568	Resolution of D-loop Structures through Holliday Junction Intermediates	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-113510	E2F mediated regulation of DNA replication	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-5694530	Cargo concentration in the ER	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-73847	Purine metabolism	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-192105	Synthesis of bile acids and bile salts	0.999999999985623	-1.43774054863831e-11	34	0	0	29	10285
R-HSA-212165	Epigenetic regulation of gene expression	0.999999999985628	-1.4371643579856e-11	151	0	0	29	10285
R-HSA-1483206	Glycerophospholipid biosynthesis	0.999999999985641	-1.43589735416707e-11	129	0	0	29	10285
R-HSA-3359454	Defective TCN2 causes hereditary megaloblastic anemia	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-162589	Reverse Transcription of HIV RNA	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5083629	Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-8853333	Signaling by FGFR2 fusions	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-211957	Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-162585	Uncoating of the HIV Virion	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-2534343	Interaction With Cumulus Cells	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5250982	Toxicity of tetanus toxin (TeNT)	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-2033515	t(4;14) translocations of FGFR3	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-389542	NADPH regeneration	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-169131	Inhibition of PKR	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-6809583	Retinoid metabolism disease events	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-2142696	Synthesis of Hepoxilins (HX) and Trioxilins (TrX)	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-112122	ALKBH2 mediated reversal of alkylation damage	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1222449	Mtb iron assimilation by chelation	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5083628	Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-2023837	Signaling by FGFR2 amplification mutants	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-164516	Minus-strand DNA synthesis	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-3359457	Defective GIF causes intrinsic factor deficiency	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-171286	Synthesis and processing of ENV and VPU	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-975574	Reactions specific to the hybrid N-glycan synthesis pathway	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1855231	Synthesis of IPs in the ER lumen	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1300645	Acrosome Reaction	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-168330	Viral RNP Complexes in the Host Cell Nucleus	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-2978092	Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5619058	Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR)	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-140180	COX reactions	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-2408552	Methylation of MeSeH for excretion	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1839120	Signaling by FGFR1 amplification mutants	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1299344	TWIK-related spinal cord K+ channel (TRESK)	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5083633	Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1839128	FGFR4 mutant receptor activation	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5263617	Metabolism of ingested MeSeO2H into MeSeH	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5602415	UNC93B1 deficiency - HSE	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5340573	WNT ligand secretion is abrogated by the PORCN inhibitor LGK974	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5602410	TLR3 deficiency - HSE	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5657655	MGMT-mediated DNA damage reversal	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1483196	PI and PC transport between ER and Golgi membranes	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1299287	Tandem pore domain halothane-inhibited K+ channel (THIK)	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5619110	Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR)	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1483076	Synthesis of CL	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5467333	APC truncation mutants are not K63 polyubiquitinated	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-3248023	Regulation by TREX1	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-2466712	Biosynthesis of A2E, implicated in retinal degradation	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-164525	Plus-strand DNA synthesis	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-3359474	Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-190840	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-163316	Mitochondrial transcription termination	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1222352	Latent infection of Homo sapiens with Mycobacterium tuberculosis	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-1222499	Response of Mtb to phagocytosis	0.999999999985705	-1.42949085728261e-11	1	0	0	29	10285
R-HSA-5696399	Global Genome Nucleotide Excision Repair (GG-NER)	0.999999999985721	-1.4279197997868e-11	85	0	0	29	10285
R-HSA-3781865	Diseases of glycosylation	0.999999999985721	-1.4279197997868e-11	85	0	0	29	10285
R-HSA-111885	Opioid Signalling	0.999999999985721	-1.4279197997868e-11	85	0	0	29	10285
R-HSA-6805567	Keratinization	0.999999999985955	-1.40452039832718e-11	214	0	0	29	10285
R-HSA-5678895	Defective CFTR causes cystic fibrosis	0.999999999985957	-1.40428834001321e-11	62	0	0	29	10285
R-HSA-6790901	rRNA modification in the nucleus and cytosol	0.999999999985957	-1.40428834001321e-11	62	0	0	29	10285
R-HSA-72187	mRNA 3'-end processing	0.999999999985957	-1.40428834001321e-11	62	0	0	29	10285
R-HSA-1445148	Translocation of GLUT4 to the plasma membrane	0.999999999985957	-1.40428834001321e-11	62	0	0	29	10285
R-HSA-72649	Translation initiation complex formation	0.999999999985957	-1.40428834001321e-11	62	0	0	29	10285
R-HSA-1268020	Mitochondrial protein import	0.999999999985957	-1.40428834001321e-11	62	0	0	29	10285
R-HSA-8852135	Protein ubiquitination	0.999999999985957	-1.40428834001321e-11	62	0	0	29	10285
R-HSA-163125	Post-translational modification: synthesis of GPI-anchored proteins	0.999999999986772	-1.32281748750693e-11	92	0	0	29	10285
R-HSA-373080	Class B/2 (Secretin family receptors)	0.999999999986772	-1.32281748750693e-11	92	0	0	29	10285
R-HSA-381119	Unfolded Protein Response (UPR)	0.999999999986772	-1.32281748750693e-11	92	0	0	29	10285
R-HSA-162599	Late Phase of HIV Life Cycle	0.999999999986808	-1.31920668636019e-11	139	0	0	29	10285
R-HSA-453274	Mitotic G2-G2/M phases	0.999999999986887	-1.31134020067307e-11	184	0	0	29	10285
R-HSA-3858494	Beta-catenin independent WNT signaling	0.99999999998705	-1.29495348589883e-11	149	0	0	29	10285
R-HSA-504046	RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	0.99999999998705	-1.29495348589883e-11	149	0	0	29	10285
R-HSA-73864	RNA Polymerase I Transcription	0.999999999987259	-1.27409521444611e-11	112	0	0	29	10285
R-HSA-157118	Signaling by NOTCH	0.999999999987259	-1.27409521444611e-11	112	0	0	29	10285
R-HSA-5696398	Nucleotide Excision Repair	0.999999999987259	-1.27409521444611e-11	112	0	0	29	10285
R-HSA-8876198	RAB GEFs exchange GTP for GDP on RABs	0.999999999987536	-1.24643559740922e-11	89	0	0	29	10285
R-HSA-190236	Signaling by FGFR	0.999999999987536	-1.24643559740922e-11	89	0	0	29	10285
R-HSA-3371556	Cellular response to heat stress	0.999999999987536	-1.24643559740922e-11	89	0	0	29	10285
R-HSA-68949	Orc1 removal from chromatin	0.999999999987702	-1.22983905140464e-11	72	0	0	29	10285
R-HSA-69052	Switching of origins to a post-replicative state	0.999999999987702	-1.22983905140464e-11	72	0	0	29	10285
R-HSA-380259	Loss of Nlp from mitotic centrosomes	0.999999999987702	-1.22983905140464e-11	72	0	0	29	10285
R-HSA-606279	Deposition of new CENPA-containing nucleosomes at the centromere	0.999999999987702	-1.22983905140464e-11	72	0	0	29	10285
R-HSA-774815	Nucleosome assembly	0.999999999987702	-1.22983905140464e-11	72	0	0	29	10285
R-HSA-69202	Cyclin E associated events during G1/S transition	0.999999999987702	-1.22983905140464e-11	72	0	0	29	10285
R-HSA-380284	Loss of proteins required for interphase microtubule organization from the centrosome	0.999999999987702	-1.22983905140464e-11	72	0	0	29	10285
R-HSA-442755	Activation of NMDA receptor upon glutamate binding and postsynaptic events	0.99999999998783	-1.21698776012829e-11	41	0	0	29	10285
R-HSA-110313	Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	0.99999999998783	-1.21698776012829e-11	41	0	0	29	10285
R-HSA-749476	RNA Polymerase III Abortive And Retractive Initiation	0.99999999998783	-1.21698776012829e-11	41	0	0	29	10285
R-HSA-5654743	Signaling by FGFR4	0.99999999998783	-1.21698776012829e-11	41	0	0	29	10285
R-HSA-74158	RNA Polymerase III Transcription	0.99999999998783	-1.21698776012829e-11	41	0	0	29	10285
R-HSA-5696400	Dual Incision in GG-NER	0.99999999998783	-1.21698776012829e-11	41	0	0	29	10285
R-HSA-5620924	Intraflagellar transport	0.99999999998783	-1.21698776012829e-11	41	0	0	29	10285
R-HSA-69620	Cell Cycle Checkpoints	0.999999999987991	-1.20084623298968e-11	201	0	0	29	10285
R-HSA-2555396	Mitotic Metaphase and Anaphase	0.999999999988144	-1.18560517442734e-11	180	0	0	29	10285
R-HSA-425393	Transport of inorganic cations/anions and amino acids/oligopeptides	0.999999999988226	-1.17735827537542e-11	107	0	0	29	10285
R-HSA-427413	NoRC negatively regulates rRNA expression	0.999999999988226	-1.17735827537542e-11	107	0	0	29	10285
R-HSA-382556	ABC-family proteins mediated transport	0.999999999988226	-1.17735827537542e-11	107	0	0	29	10285
R-HSA-211000	Gene Silencing by RNA	0.999999999988276	-1.17237419527605e-11	137	0	0	29	10285
R-HSA-8856828	Clathrin-mediated endocytosis	0.999999999988276	-1.17237419527605e-11	137	0	0	29	10285
R-HSA-5689880	Ub-specific processing proteases	0.999999999988386	-1.16139088314457e-11	223	0	0	29	10285
R-HSA-195399	VEGF binds to VEGFR leading to receptor dimerization	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-196783	Coenzyme A biosynthesis	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-1483115	Hydrolysis of LPC	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-389397	Orexin and neuropeptides FF and QRFP bind to their respective receptors	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-444821	Relaxin receptors	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-5688849	Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5)	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-1483148	Synthesis of PG	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-2408508	Metabolism of ingested SeMet, Sec, MeSec into H2Se	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-450520	HuR (ELAVL1) binds and stabilizes mRNA	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-8850843	Phosphate bond hydrolysis by NTPDase proteins	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-164944	Nef and signal transduction	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-446388	Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-446210	Synthesis of UDP-N-acetyl-glucosamine	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-77111	Synthesis of Ketone Bodies	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-72731	Recycling of eIF2:GDP	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-1236973	Cross-presentation of particulate exogenous antigens (phagosomes)	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-2142789	Ubiquinol biosynthesis	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-3656532	TGFBR1 KD Mutants in Cancer	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-210747	Regulation of gene expression in early pancreatic precursor cells	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-177128	Conjugation of salicylate with glycine	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-6787450	tRNA modification in the mitochondrion	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-5576890	Phase 3 - rapid repolarisation	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-194313	VEGF ligand-receptor interactions	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-434316	Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-400451	Free fatty acids regulate insulin secretion	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-1482883	Acyl chain remodeling of DAG and TAG	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-5632681	Ligand-receptor interactions	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-110328	Recognition and association of DNA glycosylase with site containing an affected pyrimidine	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-73928	Depyrimidination	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-196836	Vitamin C (ascorbate) metabolism	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-5358493	Synthesis of diphthamide-EEF2	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-70921	Histidine catabolism	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-5603027	IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-3656534	Loss of Function of TGFBR1 in Cancer	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-416550	Sema4D mediated inhibition of cell attachment and migration	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-5362798	Release of Hh-Np from the secreting cell	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-163680	AMPK inhibits chREBP transcriptional activation activity	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-73942	DNA Damage Reversal	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-2142670	Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-448424	Interleukin-17 signaling	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-977347	Serine biosynthesis	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-68952	DNA replication initiation	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-110329	Cleavage of the damaged pyrimidine	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-444473	Formyl peptide receptors bind formyl peptides and many other ligands	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-8937144	Aryl hydrocarbon receptor signalling	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-174430	Telomere C-strand synthesis initiation	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-5688890	Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)	0.999999999988457	-1.15424925904485e-11	8	0	0	29	10285
R-HSA-1362409	Mitochondrial iron-sulfur cluster biogenesis	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-110357	Displacement of DNA glycosylase by APEX1	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-159424	Conjugation of carboxylic acids	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-162592	Integration of provirus	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-1614558	Degradation of cysteine and homocysteine	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-8854691	Interleukin-19, 20, 22, 24	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-111453	BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-163765	ChREBP activates metabolic gene expression	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2142816	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-428543	Inactivation of Cdc42 and Rac	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2474795	Diseases associated with visual transduction	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-425986	Sodium/Proton exchangers	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2243919	Crosslinking of collagen fibrils	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2142688	Synthesis of 5-eicosatetraenoic acids	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-71336	Pentose phosphate pathway (hexose monophosphate shunt)	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-426486	Small interfering RNA (siRNA) biogenesis	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-1462054	Alpha-defensins	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-112411	MAPK1 (ERK2) activation	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-3304351	Signaling by TGF-beta Receptor Complex in Cancer	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-194002	Glucocorticoid biosynthesis	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-189085	Digestion of dietary carbohydrate	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-1300642	Sperm Motility And Taxes	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-1296052	Ca2+ activated K+ channels	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-72200	mRNA Editing: C to U Conversion	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2214320	Anchoring fibril formation	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-198693	AKT phosphorylates targets in the nucleus	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-629597	Highly calcium permeable nicotinic acetylcholine receptors	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-428890	Role of Abl in Robo-Slit signaling	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-196025	Formation of annular gap junctions	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-5340588	RNF mutants show enhanced WNT signaling and proliferation	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-1247673	Erythrocytes take up oxygen and release carbon dioxide	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-391908	Prostanoid ligand receptors	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-75094	Formation of the Editosome	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2428933	SHC-related events triggered by IGF1R	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-8849469	PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-159763	Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-447041	CHL1 interactions	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2179392	EGFR Transactivation by Gastrin	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-5666185	RHO GTPases Activate Rhotekin and Rhophilins	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-74182	Ketone body metabolism	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-166665	Terminal pathway of complement	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-419771	Opsins	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2453864	Retinoid cycle disease events	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-156587	Amino Acid conjugation	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-390696	Adrenoceptors	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-8876493	InlA-mediated entry of Listeria monocytogenes into host cells	0.999999999988504	-1.14960286836904e-11	9	0	0	29	10285
R-HSA-2262752	Cellular responses to stress	0.999999999988718	-1.12819731663883e-11	451	0	0	29	10285
R-HSA-983168	Antigen processing: Ubiquitination & Proteasome degradation	0.999999999988828	-1.11717571563488e-11	311	0	0	29	10285
R-HSA-170660	Adenylate cyclase activating pathway	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-419812	Calcitonin-like ligand receptors	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-190377	FGFR2b ligand binding and activation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-3215018	Processing and activation of SUMO	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-428643	Organic anion transporters	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-5663084	Diseases of carbohydrate metabolism	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-2046105	Linoleic acid (LA) metabolism	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-442380	Zinc influx into cells by the SLC39 gene family	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-2562578	TRIF-mediated programmed cell death	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-1660517	Synthesis of PIPs at the late endosome membrane	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-399997	Acetylcholine regulates insulin secretion	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-167590	Nef Mediated CD4 Down-regulation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-3229121	Glycogen storage diseases	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-430116	GP1b-IX-V activation signalling	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-2151209	Activation of PPARGC1A (PGC-1alpha) by phosphorylation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-5687613	Diseases associated with surfactant metabolism	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-418890	Role of second messengers in netrin-1 signaling	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-174437	Removal of the Flap Intermediate from the C-strand	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-159782	Removal of aminoterminal propeptides from gamma-carboxylated proteins	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-389887	Beta-oxidation of pristanoyl-CoA	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-450341	Activation of the AP-1 family of transcription factors	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-975578	Reactions specific to the complex N-glycan synthesis pathway	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-8875656	MET receptor recycling	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-74749	Signal attenuation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-110056	MAPK3 (ERK1) activation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-196108	Pregnenolone biosynthesis	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-1300644	Interaction With The Zona Pellucida	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-70635	Urea cycle	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-8866904	Negative regulation of activity of TFAP2 (AP-2) family transcription factors	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-139915	Activation of PUMA and translocation to mitochondria	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-112311	Neurotransmitter Clearance In The Synaptic Cleft	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-1855167	Synthesis of pyrophosphates in the cytosol	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-201688	WNT mediated activation of DVL	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-159740	Gamma-carboxylation of protein precursors	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-168799	Neurotoxicity of clostridium toxins	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-727802	Transport of nucleotide sugars	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-8853334	Signaling by FGFR3 fusions in cancer	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-3785653	Myoclonic epilepsy of Lafora	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-6811555	PI5P Regulates TP53 Acetylation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-418886	Netrin mediated repulsion signals	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-73929	Base-Excision Repair, AP Site Formation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-77286	mitochondrial fatty acid beta-oxidation of saturated fatty acids	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-190873	Gap junction degradation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-2161522	Abacavir transport and metabolism	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-74259	Purine catabolism	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-193692	Regulated proteolysis of p75NTR	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-209968	Thyroxine biosynthesis	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-2465910	MASTL Facilitates Mitotic Progression	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-111367	SLBP independent Processing of Histone Pre-mRNAs	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-390450	Folding of actin by CCT/TriC	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-425381	Bicarbonate transporters	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-937042	IRAK2 mediated activation of TAK1 complex	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-8868766	rRNA processing in the mitochondrion	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-427601	Multifunctional anion exchangers	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-113507	E2F-enabled inhibition of pre-replication complex formation	0.999999999988897	-1.11030680524707e-11	10	0	0	29	10285
R-HSA-73780	RNA Polymerase III Chain Elongation	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-5654704	SHC-mediated cascade:FGFR3	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-936964	Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-450385	Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-181429	Serotonin Neurotransmitter Release Cycle	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-5676594	TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-5654221	Phospholipase C-mediated cascade; FGFR2	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-912631	Regulation of signaling by CBL	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-181430	Norepinephrine Neurotransmitter Release Cycle	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-5635838	Activation of SMO	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-1482925	Acyl chain remodelling of PG	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-1912420	Pre-NOTCH Processing in Golgi	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-450513	Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-210993	Tie2 Signaling	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-69205	G1/S-Specific Transcription	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-2022377	Metabolism of Angiotensinogen to Angiotensins	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-1369062	ABC transporters in lipid homeostasis	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-209776	Amine-derived hormones	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-1839117	Signaling by cytosolic FGFR1 fusion mutants	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-196757	Metabolism of folate and pterines	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-197264	Nicotinamide salvaging	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-5654710	PI-3K cascade:FGFR3	0.999999999988935	-1.10645890582703e-11	18	0	0	29	10285
R-HSA-6796648	TP53 Regulates Transcription of DNA Repair Genes	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-388841	Costimulation by the CD28 family	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-5693571	Nonhomologous End-Joining (NHEJ)	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-427359	SIRT1 negatively regulates rRNA Expression	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-909733	Interferon alpha/beta signaling	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-68867	Assembly of the pre-replicative complex	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-204005	COPII (Coat Protein 2) Mediated Vesicle Transport	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-5619084	ABC transporter disorders	0.999999999989082	-1.09183989161552e-11	69	0	0	29	10285
R-HSA-5663220	RHO GTPases Activate Formins	0.999999999989258	-1.07421691623891e-11	117	0	0	29	10285
R-HSA-373752	Netrin-1 signaling	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-3928662	EPHB-mediated forward signaling	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-2426168	Activation of gene expression by SREBF (SREBP)	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-1566948	Elastic fibre formation	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-8866654	E3 ubiquitin ligases ubiquitinate target proteins	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-168253	Host Interactions with Influenza Factors	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-983189	Kinesins	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-1461957	Beta defensins	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-6782315	tRNA modification in the nucleus and cytosol	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-381676	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	0.999999999989277	-1.07228796867444e-11	42	0	0	29	10285
R-HSA-72202	Transport of Mature Transcript to Cytoplasm	0.999999999989403	-1.05966599257589e-11	87	0	0	29	10285
R-HSA-174143	APC/C-mediated degradation of cell cycle proteins	0.999999999989403	-1.05966599257589e-11	87	0	0	29	10285
R-HSA-453276	Regulation of mitotic cell cycle	0.999999999989403	-1.05966599257589e-11	87	0	0	29	10285
R-HSA-5419276	Mitochondrial translation termination	0.999999999989403	-1.05966599257589e-11	87	0	0	29	10285
R-HSA-351202	Metabolism of polyamines	0.999999999989403	-1.05966599257589e-11	87	0	0	29	10285
R-HSA-5368286	Mitochondrial translation initiation	0.999999999989403	-1.05966599257589e-11	87	0	0	29	10285
R-HSA-2467813	Separation of Sister Chromatids	0.999999999989508	-1.04918172062425e-11	168	0	0	29	10285
R-HSA-446652	Interleukin-1 signaling	0.999999999989542	-1.04576806752136e-11	46	0	0	29	10285
R-HSA-4615885	SUMOylation of DNA replication proteins	0.999999999989542	-1.04576806752136e-11	46	0	0	29	10285
R-HSA-1660662	Glycosphingolipid metabolism	0.999999999989542	-1.04576806752136e-11	46	0	0	29	10285
R-HSA-2173793	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	0.999999999989542	-1.04576806752136e-11	46	0	0	29	10285
R-HSA-70153	Glucose transport	0.999999999989542	-1.04576806752136e-11	46	0	0	29	10285
R-HSA-418555	G alpha (s) signalling events	0.999999999989722	-1.02775705670772e-11	146	0	0	29	10285
R-HSA-112314	Neurotransmitter Receptor Binding And Downstream Transmission In The  Postsynaptic Cell	0.999999999989722	-1.02775705670772e-11	146	0	0	29	10285
R-HSA-451308	Activation of Ca-permeable Kainate Receptor	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-176974	Unwinding of DNA	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-3656253	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-71384	Ethanol oxidation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-3656237	Defective EXT2 causes exostoses 2	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-1296346	Tandem pore domain potassium channels	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-6803211	TP53 Regulates Transcription of Death Receptors and Ligands	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-4641265	Repression of WNT target genes	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-5578768	Physiological factors	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-390666	Serotonin receptors	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-211979	Eicosanoids	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-5689877	Josephin domain DUBs	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-1234158	Regulation of gene expression by Hypoxia-inducible Factor	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-844456	The NLRP3 inflammasome	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-2033514	FGFR3 mutant receptor activation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-1474151	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-622323	Presynaptic nicotinic acetylcholine receptors	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-73621	Pyrimidine catabolism	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-2022857	Keratan sulfate degradation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-8851680	Butyrophilin (BTN) family interactions	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-71064	Lysine catabolism	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-166786	Creation of C4 and C2 activators	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-417957	P2Y receptors	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-75035	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-6803207	TP53 Regulates Transcription of Caspase Activators and Caspases	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-975110	TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-1475029	Reversible hydration of carbon dioxide	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-211958	Miscellaneous substrates	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-1433617	Regulation of signaling by NODAL	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-3371511	HSF1 activation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-2160916	Hyaluronan uptake and degradation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-8866427	VLDLR internalisation and degradation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-389359	CD28 dependent Vav1 pathway	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-210990	PECAM1 interactions	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-2468052	Establishment of Sister Chromatid Cohesion	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-451306	Ionotropic activity of Kainate Receptors	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-1839130	Signaling by activated point mutants of FGFR3	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-209822	Glycoprotein hormones	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-879518	Transport of organic anions	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-203615	eNOS activation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-73817	Purine ribonucleoside monophosphate biosynthesis	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-190373	FGFR1c ligand binding and activation	0.999999999989913	-1.00865790822835e-11	12	0	0	29	10285
R-HSA-168898	Toll-Like Receptors Cascades	0.999999999989957	-1.00429088094805e-11	153	0	0	29	10285
R-HSA-6804756	Regulation of TP53 Activity through Phosphorylation	0.999999999990322	-9.67781146673074e-12	93	0	0	29	10285
R-HSA-975155	MyD88 dependent cascade initiated on endosome	0.999999999990322	-9.67781146673074e-12	93	0	0	29	10285
R-HSA-1474290	Collagen formation	0.999999999990322	-9.67781146673074e-12	93	0	0	29	10285
R-HSA-5250924	B-WICH complex positively regulates rRNA expression	0.999999999990322	-9.67781146673074e-12	93	0	0	29	10285
R-HSA-168181	Toll Like Receptor 7/8 (TLR7/8) Cascade	0.999999999990322	-9.67781146673074e-12	93	0	0	29	10285
R-HSA-975138	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	0.999999999990364	-9.63579462595979e-12	91	0	0	29	10285
R-HSA-73777	RNA Polymerase I Chain Elongation	0.999999999990364	-9.63579462595979e-12	91	0	0	29	10285
R-HSA-201722	Formation of the beta-catenin:TCF transactivating complex	0.999999999990364	-9.63579462595979e-12	91	0	0	29	10285
R-HSA-450531	Regulation of mRNA stability by proteins that bind AU-rich elements	0.999999999990364	-9.63579462595979e-12	91	0	0	29	10285
R-HSA-2980736	Peptide hormone metabolism	0.999999999990364	-9.63579462595979e-12	91	0	0	29	10285
R-HSA-400206	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	0.999999999990875	-9.12515796887853e-12	127	0	0	29	10285
R-HSA-5693538	Homology Directed Repair	0.999999999991083	-8.91680146715208e-12	138	0	0	29	10285
R-HSA-5358351	Signaling by Hedgehog	0.999999999991083	-8.91680146715208e-12	138	0	0	29	10285
R-HSA-5173214	O-glycosylation of TSR domain-containing proteins	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-5674135	MAP2K and MAPK activation	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-6783310	Fanconi Anemia Pathway	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-5696394	DNA Damage Recognition in GG-NER	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-983695	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-6802946	Signaling by moderate kinase activity BRAF mutants	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-140877	Formation of Fibrin Clot (Clotting Cascade)	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-165159	mTOR signalling	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-69236	G1 Phase	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-69231	Cyclin D associated events in G1	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-420499	Class C/3 (Metabotropic glutamate/pheromone receptors)	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-111465	Apoptotic cleavage of cellular proteins	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-163841	Gamma carboxylation, hypusine formation and arylsulfatase activation	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-6802955	Paradoxical activation of RAF signaling by kinase inactive BRAF	0.999999999991098	-8.90184823214372e-12	39	0	0	29	10285
R-HSA-5654712	FRS-mediated FGFR4 signaling	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-5620916	VxPx cargo-targeting to cilium	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-1482801	Acyl chain remodelling of PS	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-5621575	CD209 (DC-SIGN) signaling	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-389513	CTLA4 inhibitory signaling	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-389357	CD28 dependent PI3K/Akt signaling	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-373753	Nephrin interactions	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-69273	Cyclin A/B1 associated events during G2/M transition	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-77289	Mitochondrial Fatty Acid Beta-Oxidation	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-166208	mTORC1-mediated signalling	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-140837	Intrinsic Pathway of Fibrin Clot Formation	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-2142691	Synthesis of Leukotrienes (LT) and Eoxins (EX)	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-4641263	Regulation of FZD by ubiquitination	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-901032	ER Quality Control Compartment (ERQC)	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-202427	Phosphorylation of CD3 and TCR zeta chains	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-8853338	Signaling by FGFR3 point mutants in cancer	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-202131	Metabolism of nitric oxide	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-140875	Common Pathway of Fibrin Clot Formation	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-203765	eNOS activation and regulation	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-166663	Initial triggering of complement	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-5655332	Signaling by FGFR3 in disease	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-77595	Processing of Intronless Pre-mRNAs	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-198753	ERK/MAPK targets	0.999999999991211	-8.78911052685461e-12	22	0	0	29	10285
R-HSA-6783783	Interleukin-10 signaling	0.999999999991548	-8.45189799777718e-12	49	0	0	29	10285
R-HSA-71406	Pyruvate metabolism and Citric Acid (TCA) cycle	0.999999999991548	-8.45189799777718e-12	49	0	0	29	10285
R-HSA-6811440	Retrograde transport at the Trans-Golgi-Network	0.999999999991548	-8.45189799777718e-12	49	0	0	29	10285
R-HSA-6791312	TP53 Regulates Transcription of Cell Cycle Genes	0.999999999991548	-8.45189799777718e-12	49	0	0	29	10285
R-HSA-72203	Processing of Capped Intron-Containing Pre-mRNA	0.999999999991597	-8.40333675525993e-12	247	0	0	29	10285
R-HSA-68827	CDT1 association with the CDC6:ORC:origin complex	0.999999999991609	-8.39075527898163e-12	60	0	0	29	10285
R-HSA-6802952	Signaling by BRAF and RAF fusions	0.999999999991609	-8.39075527898163e-12	60	0	0	29	10285
R-HSA-5387390	Hh mutants abrogate ligand secretion	0.999999999991609	-8.39075527898163e-12	60	0	0	29	10285
R-HSA-193648	NRAGE signals death through JNK	0.999999999991609	-8.39075527898163e-12	60	0	0	29	10285
R-HSA-5676590	NIK-->noncanonical NF-kB signaling	0.999999999991609	-8.39075527898163e-12	60	0	0	29	10285
R-HSA-2022090	Assembly of collagen fibrils and other multimeric structures	0.999999999991609	-8.39075527898163e-12	60	0	0	29	10285
R-HSA-6784531	tRNA processing in the nucleus	0.999999999991609	-8.39075527898163e-12	60	0	0	29	10285
R-HSA-427975	Proton/oligopeptide cotransporters	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-3878781	Glycogen storage disease type IV (GBE1)	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-6807062	Cholesterol biosynthesis via lathosterol	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-112313	Neurotransmitter uptake and Metabolism In Glial Cells	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-209563	Axonal growth stimulation	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-1296053	Classical Kir channels	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-167060	NGF processing	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-211163	AKT-mediated inactivation of FOXO1A	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-2473224	Antagonism of Activin by Follistatin	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-8847453	Synthesis of PIPs in the nucleus	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-5083630	Defective LFNG causes SCDO3	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-209905	Catecholamine biosynthesis	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-8848584	Wax biosynthesis	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-5250968	Toxicity of botulinum toxin type A (BoNT/A)	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-110381	Resolution of AP sites via the single-nucleotide replacement pathway	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-8935690	Miscellaneous digestion events	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-3000497	Scavenging by Class H Receptors	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-447115	Interleukin-12 signaling	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-428542	Regulation of Commissural axon pathfinding by Slit and Robo	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-2408550	Metabolism of ingested H2SeO4 and H2SeO3 into H2Se	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-194306	Neurophilin interactions with VEGF and VEGFR	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-75108	Activation, myristolyation of BID and translocation to mitochondria	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-1369007	Mitochondrial ABC transporters	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-69895	Transcriptional  activation of  cell cycle inhibitor p21	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-1855191	Synthesis of IPs in the nucleus	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-173107	Binding and entry of HIV virion	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-6807047	Cholesterol biosynthesis via desmosterol	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-6802953	RAS signaling downstream of NF1 loss-of-function variants	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-140179	Amine Oxidase reactions	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-69560	Transcriptional activation of p53 responsive genes	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-390650	Histamine receptors	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-446343	Localization of the PINCH-ILK-PARVIN complex to focal adhesions	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-75944	Transcription from mitochondrial promoters	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-399710	Activation of AMPA receptors	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-173736	Alternative complement activation	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-204626	Hypusine synthesis from eIF5A-lysine	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-4551638	SUMOylation of chromatin organization proteins	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-8866906	TFAP2 (AP-2) family regulates transcription of other transcription factors	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-112126	ALKBH3 mediated reversal of alkylation damage	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-888593	Reuptake of GABA	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-69200	Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-442745	Activation of CaMK IV	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-8849474	PTK6 Activates STAT3	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-6783984	Glycine degradation	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-6803544	Ion influx/efflux at host-pathogen interface	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-1251932	PLCG1 events in ERBB2 signaling	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-5579026	Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-1296025	ATP sensitive Potassium channels	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-379401	Dopamine clearance from the synaptic cleft	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-5603037	IRAK4 deficiency (TLR5)	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-417973	Adenosine P1 receptors	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-176034	Interactions of Tat with host cellular proteins	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-428776	Class II GLUTs	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-1296061	HCN channels	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-165158	Activation of AKT2	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-5619099	Defective AVP causes neurohypophyseal diabetes insipidus (NDI)	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-5221030	TET1,2,3 and TDG demethylate DNA	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-210455	Astrocytic Glutamate-Glutamine Uptake And Metabolism	0.999999999991653	-8.34723489851449e-12	4	0	0	29	10285
R-HSA-429914	Deadenylation-dependent mRNA decay	0.999999999991753	-8.24718565487206e-12	57	0	0	29	10285
R-HSA-450408	AUF1 (hnRNP D0) binds and destabilizes mRNA	0.999999999991753	-8.24718565487206e-12	57	0	0	29	10285
R-HSA-170834	Signaling by TGF-beta Receptor Complex	0.999999999991824	-8.17595805142632e-12	77	0	0	29	10285
R-HSA-167172	Transcription of the HIV genome	0.999999999991824	-8.17595805142632e-12	77	0	0	29	10285
R-HSA-1234174	Regulation of Hypoxia-inducible Factor (HIF) by oxygen	0.999999999991824	-8.17595805142632e-12	77	0	0	29	10285
R-HSA-69304	Regulation of DNA replication	0.999999999991824	-8.17595805142632e-12	77	0	0	29	10285
R-HSA-176814	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	0.999999999991824	-8.17595805142632e-12	77	0	0	29	10285
R-HSA-2262749	Cellular response to hypoxia	0.999999999991824	-8.17595805142632e-12	77	0	0	29	10285
R-HSA-195721	Signaling by Wnt	0.999999999992035	-7.96464894568349e-12	336	0	0	29	10285
R-HSA-4641257	Degradation of AXIN	0.999999999992261	-7.73941475677254e-12	56	0	0	29	10285
R-HSA-174113	SCF-beta-TrCP mediated degradation of Emi1	0.999999999992261	-7.73941475677254e-12	56	0	0	29	10285
R-HSA-5578775	Ion homeostasis	0.999999999992261	-7.73941475677254e-12	56	0	0	29	10285
R-HSA-69541	Stabilization of p53	0.999999999992261	-7.73941475677254e-12	56	0	0	29	10285
R-HSA-381038	XBP1(S) activates chaperone genes	0.999999999992261	-7.73941475677254e-12	56	0	0	29	10285
R-HSA-8854050	FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	0.999999999992261	-7.73941475677254e-12	56	0	0	29	10285
R-HSA-977443	GABA receptor activation	0.999999999992261	-7.73941475677254e-12	56	0	0	29	10285
R-HSA-162587	HIV Life Cycle	0.999999999992277	-7.72290088151344e-12	152	0	0	29	10285
R-HSA-6803204	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-5654689	PI-3K cascade:FGFR1	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-5423646	Aflatoxin activation and detoxification	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-6807004	Negative regulation of MET activity	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-500657	Presynaptic function of Kainate receptors	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-2022870	Chondroitin sulfate biosynthesis	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-8849932	SALM protein interactions at the synapses	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-5654688	SHC-mediated cascade:FGFR1	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-196741	Cobalamin (Cbl, vitamin B12) transport and metabolism	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-5651801	PCNA-Dependent Long Patch Base Excision Repair	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-2024096	HS-GAG degradation	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-1181150	Signaling by NODAL	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-210745	Regulation of gene expression in beta cells	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-69618	Mitotic Spindle Checkpoint	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-2979096	NOTCH2 Activation and Transmission of Signal to the Nucleus	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-445144	Signal transduction by L1	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-2028269	Signaling by Hippo	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-1810476	RIP-mediated NFkB activation via ZBP1	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-381426	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-6804115	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.999999999992328	-7.67221443585802e-12	21	0	0	29	10285
R-HSA-381340	Transcriptional regulation of white adipocyte differentiation	0.999999999992424	-7.57609606996146e-12	88	0	0	29	10285
R-HSA-416482	G alpha (12/13) signalling events	0.999999999992424	-7.57609606996146e-12	88	0	0	29	10285
R-HSA-912446	Meiotic recombination	0.999999999992424	-7.57609606996146e-12	88	0	0	29	10285
R-HSA-674695	RNA Polymerase II Pre-transcription Events	0.999999999992424	-7.57609606996146e-12	88	0	0	29	10285
R-HSA-5389840	Mitochondrial translation elongation	0.999999999992424	-7.57609606996146e-12	88	0	0	29	10285
R-HSA-416476	G alpha (q) signalling events	0.999999999992548	-7.45194765900031e-12	192	0	0	29	10285
R-HSA-5617833	Cilium Assembly	0.999999999992548	-7.45194765900031e-12	192	0	0	29	10285
R-HSA-381753	Olfactory Signaling Pathway	0.999999999992774	-7.22626534481774e-12	391	0	0	29	10285
R-HSA-73894	DNA Repair	0.999999999992972	-7.02835622769914e-12	316	0	0	29	10285
R-HSA-6811442	Intra-Golgi and retrograde Golgi-to-ER traffic	0.999999999993454	-6.54594783367565e-12	179	0	0	29	10285
R-HSA-68882	Mitotic Anaphase	0.999999999993454	-6.54594783367565e-12	179	0	0	29	10285
R-HSA-201681	TCF dependent signaling in response to WNT	0.999999999993762	-6.23833664892141e-12	238	0	0	29	10285
R-HSA-2500257	Resolution of Sister Chromatid Cohesion	0.999999999994079	-5.92097902284767e-12	103	0	0	29	10285
R-HSA-2132295	MHC class II antigen presentation	0.999999999994079	-5.92097902284767e-12	103	0	0	29	10285
R-HSA-1169091	Activation of NF-kappaB in B cells	0.999999999994178	-5.82232732263061e-12	68	0	0	29	10285
R-HSA-174154	APC/C:Cdc20 mediated degradation of Securin	0.999999999994178	-5.82232732263061e-12	68	0	0	29	10285
R-HSA-373755	Semaphorin interactions	0.999999999994178	-5.82232732263061e-12	68	0	0	29	10285
R-HSA-5685942	HDR through Homologous Recombination (HRR)	0.999999999994178	-5.82232732263061e-12	68	0	0	29	10285
R-HSA-1834949	Cytosolic sensors of pathogen-associated DNA	0.999999999994178	-5.82232732263061e-12	68	0	0	29	10285
R-HSA-211897	Cytochrome P450 - arranged by substrate type	0.999999999994178	-5.82232732263061e-12	68	0	0	29	10285
R-HSA-71387	Metabolism of carbohydrates	0.999999999994188	-5.81185585096465e-12	296	0	0	29	10285
R-HSA-500792	GPCR ligand binding	0.999999999994335	-5.66527056025643e-12	453	0	0	29	10285
R-HSA-5633007	Regulation of TP53 Activity	0.99999999999468	-5.31974292822057e-12	162	0	0	29	10285
R-HSA-2871809	FCERI mediated Ca+2 mobilization	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-157858	Gap junction trafficking and regulation	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-5654696	Downstream signaling of activated FGFR2	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-917977	Transferrin endocytosis and recycling	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-1912408	Pre-NOTCH Transcription and Translation	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-5683826	Surfactant metabolism	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-420092	Glucagon-type ligand receptors	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-110314	Recognition of DNA damage by PCNA-containing replication complex	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-2122948	Activated NOTCH1 Transmits Signal to the Nucleus	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-420029	Tight junction interactions	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-8866652	Synthesis of active ubiquitin: roles of E1 and E2 enzymes	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-5669034	TNFs bind their physiological receptors	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-111996	Ca-dependent events	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-381042	PERK regulates gene expression	0.999999999994813	-5.18699101741724e-12	30	0	0	29	10285
R-HSA-5687128	MAPK6/MAPK4 signaling	0.999999999994865	-5.13480810555287e-12	90	0	0	29	10285
R-HSA-2565942	Regulation of PLK1 Activity at G2/M Transition	0.999999999994865	-5.13480810555287e-12	90	0	0	29	10285
R-HSA-428157	Sphingolipid metabolism	0.999999999994865	-5.13480810555287e-12	90	0	0	29	10285
R-HSA-5693567	HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)	0.999999999994889	-5.11130653960324e-12	132	0	0	29	10285
R-HSA-913709	O-linked glycosylation of mucins	0.999999999994924	-5.07633983101006e-12	65	0	0	29	10285
R-HSA-69580	p53-Dependent G1/S DNA damage checkpoint	0.999999999994924	-5.07633983101006e-12	65	0	0	29	10285
R-HSA-69563	p53-Dependent G1 DNA Damage Response	0.999999999994924	-5.07633983101006e-12	65	0	0	29	10285
R-HSA-5334118	DNA methylation	0.999999999994924	-5.07633983101006e-12	65	0	0	29	10285
R-HSA-6782210	Gap-filling DNA repair synthesis and ligation in TC-NER	0.999999999994924	-5.07633983101006e-12	65	0	0	29	10285
R-HSA-112382	Formation of RNA Pol II elongation complex	0.999999999994924	-5.07633983101006e-12	65	0	0	29	10285
R-HSA-75955	RNA Polymerase II Transcription Elongation	0.999999999994924	-5.07633983101006e-12	65	0	0	29	10285
R-HSA-5362517	Signaling by Retinoic Acid	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-5696395	Formation of Incision Complex in GG-NER	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-375280	Amine ligand-binding receptors	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-432040	Vasopressin regulates renal water homeostasis via Aquaporins	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-168325	Viral Messenger RNA Synthesis	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-5693579	Homologous DNA Pairing and Strand Exchange	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-75893	TNF signaling	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-194068	Bile acid and bile salt metabolism	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-5655253	Signaling by FGFR2 in disease	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-6814122	Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-3769402	Deactivation of the beta-catenin transactivating complex	0.999999999994982	-5.01838992661119e-12	43	0	0	29	10285
R-HSA-69275	G2/M Transition	0.99999999999511	-4.8904010071868e-12	182	0	0	29	10285
R-HSA-192456	Digestion of dietary lipid	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-416993	Trafficking of GluR2-containing AMPA receptors	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5655862	Translesion synthesis by POLK	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-442729	CREB phosphorylation through the activation of CaMKII	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5083636	Defective GALNT12 causes colorectal cancer 1 (CRCS1)	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-2033519	Activated point mutants of FGFR2	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5656121	Translesion synthesis by POLI	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-2142845	Hyaluronan metabolism	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-435354	Zinc transporters	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5625900	RHO GTPases activate CIT	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-1482922	Acyl chain remodelling of PI	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-164378	PKA activation in glucagon signalling	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-156711	Polo-like kinase mediated events	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5083625	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-70221	Glycogen breakdown (glycogenolysis)	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-193639	p75NTR signals via NF-kB	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-189445	Metabolism of porphyrins	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5627117	RHO GTPases Activate ROCKs	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-3296482	Defects in vitamin and cofactor metabolism	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-438066	Unblocking of NMDA receptor, glutamate binding and activation	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-139853	Elevation of cytosolic Ca2+ levels	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-140534	Ligand-dependent caspase activation	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-937072	TRAF6 mediated induction of TAK1 complex	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-432142	Platelet sensitization by LDL	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-264642	Acetylcholine Neurotransmitter Release Cycle	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-111931	PKA-mediated phosphorylation of CREB	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-429958	mRNA decay by 3' to 5' exoribonuclease	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5083632	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-196299	Beta-catenin phosphorylation cascade	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-199220	Vitamin B5 (pantothenate) metabolism	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-622312	Inflammasomes	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-3232118	SUMOylation of transcription factors	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-2173791	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	0.999999999995142	-4.85776127945751e-12	17	0	0	29	10285
R-HSA-5688426	Deubiquitination	0.999999999995231	-4.76887842962253e-12	301	0	0	29	10285
R-HSA-175474	Assembly Of The HIV Virion	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-381033	ATF6 (ATF6-alpha) activates chaperones	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-211227	Activation of DNA fragmentation factor	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-202670	ERKs are inactivated	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5654227	Phospholipase C-mediated cascade; FGFR3	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-400511	Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-350054	Notch-HLH transcription pathway	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-8866907	Activation of the TFAP2 (AP-2) family of transcription factors	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2995410	Nuclear Envelope Reassembly	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-391160	Signal regulatory protein (SIRP) family interactions	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-1663150	The activation of arylsulfatases	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5658623	FGFRL1 modulation of FGFR1 signaling	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-432047	Passive transport by Aquaporins	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2892247	POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-879415	Advanced glycosylation endproduct receptor signaling	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-3134963	DEx/H-box helicases activate type I IFN and inflammatory cytokines production	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2408517	SeMet incorporation into proteins	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-3270619	IRF3-mediated induction of type I IFN	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5357786	TNFR1-induced proapoptotic signaling	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5668599	RHO GTPases Activate NADPH Oxidases	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5210891	Uptake and function of anthrax toxins	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-425561	Sodium/Calcium exchangers	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-75205	Dissolution of Fibrin Clot	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-977441	GABA A receptor activation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5140745	WNT5A-dependent internalization of FZD2, FZD5 and ROR2	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2029481	FCGR activation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-75892	Platelet Adhesion to exposed collagen	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-1480926	O2/CO2 exchange in erythrocytes	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5626467	RHO GTPases activate IQGAPs	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-264870	Caspase-mediated cleavage of cytoskeletal proteins	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-113501	Inhibition of replication initiation of damaged DNA by RB1/E2F1	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-74217	Purine salvage	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-375281	Hormone ligand-binding receptors	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-1502540	Signaling by Activin	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-171007	p38MAPK events	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-190372	FGFR3c ligand binding and activation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-140342	Apoptosis induced DNA fragmentation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-198323	AKT phosphorylates targets in the cytosol	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-71240	Tryptophan catabolism	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-1358803	Downregulation of ERBB2:ERBB3 signaling	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-5607763	CLEC7A (Dectin-1) induces NFAT activation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-190239	FGFR3 ligand binding and activation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-1237044	Erythrocytes take up carbon dioxide and release oxygen	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2995383	Initiation of Nuclear Envelope Reformation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-190375	FGFR2c ligand binding and activation	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-112308	Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2197563	NOTCH2 intracellular domain regulates transcription	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2168880	Scavenging of heme from plasma	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-2564830	Cytosolic iron-sulfur cluster assembly	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-6804116	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-933543	NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	0.999999999995564	-4.43603589877684e-12	13	0	0	29	10285
R-HSA-1834941	STING mediated induction of host immune responses	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5654219	Phospholipase C-mediated cascade: FGFR1	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-159418	Recycling of bile acids and salts	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-399956	CRMPs in Sema3A signaling	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5213460	RIPK1-mediated regulated necrosis	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-1170546	Prolactin receptor signaling	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-399954	Sema3A PAK dependent Axon repulsion	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5637810	Constitutive Signaling by EGFRvIII	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-163615	PKA activation	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-1433559	Regulation of KIT signaling	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5218859	Regulated Necrosis	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-392517	Rap1 signalling	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-190242	FGFR1 ligand binding and activation	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-549132	Organic cation/anion/zwitterion transport	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-446353	Cell-extracellular matrix interactions	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-110312	Translesion synthesis by REV1	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-8866910	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-162710	Synthesis of glycosylphosphatidylinositol (GPI)	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-418038	Nucleotide-like (purinergic) receptors	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-918233	TRAF3-dependent IRF activation pathway	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-2559584	Formation of Senescence-Associated Heterochromatin Foci (SAHF)	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-354194	GRB2:SOS provides linkage to MAPK signaling for Integrins	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-372708	p130Cas linkage to MAPK signaling for integrins	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5684264	MAP3K8 (TPL2)-dependent MAPK1/3 activation	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-975163	IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-1295596	Spry regulation of FGF signaling	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5637812	Signaling by EGFRvIII in Cancer	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-163210	Formation of ATP by chemiosmotic coupling	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5686938	Regulation of TLR by endogenous ligand	0.999999999995856	-4.1435316230622e-12	16	0	0	29	10285
R-HSA-5357801	Programmed Cell Death	0.999999999995893	-4.10719526939668e-12	175	0	0	29	10285
R-HSA-196854	Metabolism of vitamins and cofactors	0.999999999996148	-3.85208572637776e-12	174	0	0	29	10285
R-HSA-6785807	Interleukin-4 and 13 signaling	0.999999999996545	-3.45465374440706e-12	111	0	0	29	10285
R-HSA-68877	Mitotic Prometaphase	0.999999999996545	-3.45465374440706e-12	111	0	0	29	10285
R-HSA-163685	Integration of energy metabolism	0.999999999996545	-3.45465374440706e-12	111	0	0	29	10285
R-HSA-73857	RNA Polymerase II Transcription	0.9999999999966	-3.39966152433787e-12	159	0	0	29	10285
R-HSA-69481	G2/M Checkpoints	0.999999999996674	-3.32639325289311e-12	169	0	0	29	10285
R-HSA-68886	M Phase	0.999999999996768	-3.23165286860845e-12	308	0	0	29	10285
R-HSA-72172	mRNA Splicing	0.999999999997117	-2.88300868071146e-12	195	0	0	29	10285
R-HSA-195253	Degradation of beta-catenin by the destruction complex	0.999999999997228	-2.77215726127373e-12	83	0	0	29	10285
R-HSA-5654741	Signaling by FGFR3	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-977444	GABA B receptor activation	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-167287	HIV elongation arrest and recovery	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-1442490	Collagen degradation	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-168276	NS1 Mediated Effects on Host Pathways	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-5693616	Presynaptic phase of homologous DNA pairing and strand exchange	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-109703	PKB-mediated events	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-167290	Pausing and recovery of HIV elongation	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-390471	Association of TriC/CCT with target proteins during biosynthesis	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-8864260	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-991365	Activation of GABAB receptors	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-5675221	Negative regulation of MAPK pathway	0.999999999997296	-2.70409653942624e-12	40	0	0	29	10285
R-HSA-196849	Metabolism of water-soluble vitamins and cofactors	0.999999999997337	-2.66341223073479e-12	122	0	0	29	10285
R-HSA-390918	Peroxisomal lipid metabolism	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-72086	mRNA Capping	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-5218920	VEGFR2 mediated vascular permeability	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-5601884	PIWI-interacting RNA (piRNA) biogenesis	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-442742	CREB phosphorylation through the activation of Ras	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-5654732	Negative regulation of FGFR3 signaling	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-389957	Prefoldin mediated transfer of substrate  to CCT/TriC	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-445989	TAK1 activates NFkB by phosphorylation and activation of IKKs complex	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-2032785	YAP1- and WWTR1 (TAZ)-stimulated gene expression	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-202040	G-protein activation	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-1482839	Acyl chain remodelling of PE	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-196807	Nicotinate metabolism	0.999999999997977	-2.02275909047216e-12	29	0	0	29	10285
R-HSA-418592	ADP signalling through P2Y purinoceptor 1	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-5654708	Downstream signaling of activated FGFR3	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-3295583	TRP channels	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-167242	Abortive elongation of HIV-1 transcript in the absence of Tat	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-5673000	RAF activation	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-5654700	FRS-mediated FGFR2 signaling	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-425410	Metal ion SLC transporters	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-982772	Growth hormone receptor signaling	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-499943	Synthesis and interconversion of nucleotide di- and triphosphates	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-203927	MicroRNA (miRNA) biogenesis	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-997272	Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-5674400	Constitutive Signaling by AKT1 E17K in Cancer	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-1538133	G0 and Early G1	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-1606322	ZBP1(DAI) mediated induction of type I IFNs	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-179409	APC-Cdc20 mediated degradation of Nek2A	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-162588	Budding and maturation of HIV virion	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-211981	Xenobiotics	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-182971	EGFR downregulation	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-429947	Deadenylation of mRNA	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-389661	Glyoxylate metabolism and glycine degradation	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-977068	Termination of O-glycan biosynthesis	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-5696397	Gap-filling DNA repair synthesis and ligation in GG-NER	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-933542	TRAF6 mediated NF-kB activation	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-1614635	Sulfur amino acid metabolism	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-198725	Nuclear Events (kinase and transcription factor activation)	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-1296059	G protein gated Potassium channels	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-1296041	Activation of G protein gated Potassium channels	0.999999999998077	-1.92291715367444e-12	25	0	0	29	10285
R-HSA-69242	S Phase	0.999999999998109	-1.89102725510785e-12	130	0	0	29	10285
R-HSA-211859	Biological oxidations	0.999999999998254	-1.7463462453018e-12	222	0	0	29	10285
R-HSA-202403	TCR signaling	0.99999999999834	-1.65953256701584e-12	119	0	0	29	10285
R-HSA-69206	G1/S Transition	0.99999999999834	-1.65953256701584e-12	119	0	0	29	10285
R-HSA-190861	Gap junction assembly	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-5576886	Phase 4 - resting membrane potential	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-71403	Citric acid cycle (TCA cycle)	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-3560783	Defective B4GALT7 causes EDS, progeroid type	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-202430	Translocation of ZAP-70 to Immunological synapse	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-8876725	Protein methylation	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-450604	KSRP (KHSRP) binds and destabilizes mRNA	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-3560801	Defective B3GAT3 causes JDSSDHD	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-156584	Cytosolic sulfonation of small molecules	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-176407	Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-450321	JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-176412	Phosphorylation of the APC/C	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-110320	Translesion Synthesis by POLH	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-422085	Synthesis, secretion, and deacylation of Ghrelin	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-5223345	Miscellaneous transport and binding events	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-442660	Na+/Cl- dependent neurotransmitter transporters	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-1660514	Synthesis of PIPs at the Golgi membrane	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-3928664	Ephrin signaling	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-4420332	Defective B3GALT6 causes EDSP2 and SEMDJL1	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-8851708	Signaling by FGFR2 IIIa TM	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-442982	Ras activation uopn Ca2+ infux through NMDA receptor	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-392851	Prostacyclin signalling through prostacyclin receptor	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-888590	GABA synthesis, release, reuptake and degradation	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-416700	Other semaphorin interactions	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-6804114	TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	0.999999999998401	-1.59890885695706e-12	19	0	0	29	10285
R-HSA-212300	PRC2 methylates histones and DNA	0.999999999998837	-1.16279084385223e-12	74	0	0	29	10285
R-HSA-69300	Removal of licensing factors from origins	0.999999999998837	-1.16279084385223e-12	74	0	0	29	10285
R-HSA-6802957	Oncogenic MAPK signaling	0.999999999998837	-1.16279084385223e-12	74	0	0	29	10285
R-HSA-174824	Lipoprotein metabolism	0.999999999998837	-1.16279084385223e-12	74	0	0	29	10285
R-HSA-2299718	Condensation of Prophase Chromosomes	0.999999999998837	-1.16279084385223e-12	74	0	0	29	10285
R-HSA-179419	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	0.999999999998837	-1.16279084385223e-12	74	0	0	29	10285
R-HSA-1980143	Signaling by NOTCH1	0.999999999999119	-8.81118141477464e-13	73	0	0	29	10285
R-HSA-174178	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	0.999999999999119	-8.81118141477464e-13	73	0	0	29	10285
R-HSA-3214841	PKMTs methylate histone lysines	0.999999999999119	-8.81118141477464e-13	73	0	0	29	10285
R-HSA-6807505	RNA polymerase II transcribes snRNA genes	0.999999999999119	-8.81118141477464e-13	73	0	0	29	10285
R-HSA-174184	Cdc20:Phospho-APC/C mediated degradation of Cyclin A	0.999999999999119	-8.81118141477464e-13	73	0	0	29	10285
R-HSA-5654726	Negative regulation of FGFR1 signaling	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-389356	CD28 co-stimulation	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-202433	Generation of second messenger molecules	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-186712	Regulation of beta-cell development	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-1222556	ROS, RNS production in phagocytes	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-163359	Glucagon signaling in metabolic regulation	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-1638074	Keratan sulfate/keratin metabolism	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-1980145	Signaling by NOTCH2	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-5357905	Regulation of TNFR1 signaling	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-180746	Nuclear import of Rev protein	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-392518	Signal amplification	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-1839126	FGFR2 mutant receptor activation	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-4085001	Sialic acid metabolism	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-180910	Vpr-mediated nuclear import of PICs	0.999999999999144	-8.55589469640375e-13	33	0	0	29	10285
R-HSA-983712	Ion channel transport	0.999999999999265	-7.35281632770572e-13	209	0	0	29	10285
R-HSA-73772	RNA Polymerase I Promoter Escape	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-6804758	Regulation of TP53 Activity through Acetylation	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-1296065	Inwardly rectifying K+ channels	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-168271	Transport of Ribonucleoproteins into the Host Nucleus	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-180786	Extension of Telomeres	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-75067	Processing of Capped Intronless Pre-mRNA	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-352230	Amino acid transport across the plasma membrane	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-70614	Amino acid synthesis and interconversion (transamination)	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-450282	MAPK targets/ Nuclear events mediated by MAP kinases	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-2129379	Molecules associated with elastic fibres	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-1839124	FGFR1 mutant receptor activation	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-114452	Activation of BH3-only proteins	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-170822	Regulation of Glucokinase by Glucokinase Regulatory Protein	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-5654733	Negative regulation of FGFR4 signaling	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-2022928	HS-GAG biosynthesis	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-168333	NEP/NS2 Interacts with the Cellular Export Machinery	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-5654687	Downstream signaling of activated FGFR1	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-418360	Platelet calcium homeostasis	0.999999999999418	-5.81833720928998e-13	31	0	0	29	10285
R-HSA-397014	Muscle contraction	0.999999999999974	-2.64636636357345e-14	204	0	0	29	10285
R-HSA-5619507	Activation of HOX genes during differentiation	1.00000000000019	1.87968999515951e-13	126	0	0	29	10285
R-HSA-5617472	Activation of anterior HOX genes in hindbrain development during early embryogenesis	1.00000000000019	1.87968999515951e-13	126	0	0	29	10285
R-HSA-2559580	Oxidative Stress Induced Senescence	1.00000000000019	1.87968999515951e-13	126	0	0	29	10285
R-HSA-166016	Toll Like Receptor 4 (TLR4) Cascade	1.00000000000019	1.87968999515951e-13	126	0	0	29	10285
R-HSA-5173105	O-linked glycosylation	1.00000000000031	3.14703639496845e-13	114	0	0	29	10285
R-HSA-4086400	PCP/CE pathway	1.00000000000055	5.48244290939473e-13	96	0	0	29	10285
R-HSA-73887	Death Receptor Signalling	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-73893	DNA Damage Bypass	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-6802949	Signaling by RAS mutants	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-5654736	Signaling by FGFR1	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-167169	HIV Transcription Elongation	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-167200	Formation of HIV-1 elongation complex containing HIV-1 Tat	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-1660499	Synthesis of PIPs at the plasma membrane	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-167246	Tat-mediated elongation of the HIV-1 transcript	1.00000000000062	6.17253039081935e-13	50	0	0	29	10285
R-HSA-450294	MAP kinase activation in TLR cascade	1.00000000000067	6.72430545587097e-13	64	0	0	29	10285
R-HSA-174084	Autodegradation of Cdh1 by Cdh1:APC/C	1.00000000000067	6.72430545587097e-13	64	0	0	29	10285
R-HSA-8873719	RAB geranylgeranylation	1.00000000000067	6.72430545587097e-13	64	0	0	29	10285
R-HSA-76009	Platelet Aggregation (Plug Formation)	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-156590	Glutathione conjugation	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-167243	Tat-mediated HIV elongation arrest and recovery	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-5655302	Signaling by FGFR1 in disease	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-167238	Pausing and recovery of Tat-mediated HIV elongation	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-5689901	Metalloprotease DUBs	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-3299685	Detoxification of Reactive Oxygen Species	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-5685938	HDR through Single Strand Annealing (SSA)	1.00000000000068	6.81699044210378e-13	38	0	0	29	10285
R-HSA-202733	Cell surface interactions at the vascular wall	1.0000000000007	7.02650879059133e-13	136	0	0	29	10285
R-HSA-168164	Toll Like Receptor 3 (TLR3) Cascade	1.00000000000237	2.37220652051913e-12	99	0	0	29	10285
R-HSA-937061	TRIF-mediated TLR3/TLR4 signaling	1.00000000000237	2.37220652051913e-12	99	0	0	29	10285
R-HSA-390466	Chaperonin-mediated protein folding	1.00000000000237	2.37220652051913e-12	99	0	0	29	10285
R-HSA-166166	MyD88-independent TLR3/TLR4 cascade	1.00000000000237	2.37220652051913e-12	99	0	0	29	10285
R-HSA-8856825	Cargo recognition for clathrin-mediated endocytosis	1.00000000000237	2.37220652051913e-12	99	0	0	29	10285
R-HSA-445717	Aquaporin-mediated transport	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-69017	CDK-mediated phosphorylation and removal of Cdc6	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-2980766	Nuclear Envelope Breakdown	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-3214842	HDMs demethylate histones	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-75815	Ubiquitin-dependent degradation of Cyclin D	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-350562	Regulation of ornithine decarboxylase (ODC)	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-167152	Formation of HIV elongation complex in the absence of HIV Tat	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-69229	Ubiquitin-dependent degradation of Cyclin D1	1.00000000000276	2.75834145608196e-12	52	0	0	29	10285
R-HSA-109581	Apoptosis	1.00000000000288	2.8797235756595e-12	172	0	0	29	10285
R-HSA-375276	Peptide ligand-binding receptors	1.00000000000322	3.21712656171491e-12	188	0	0	29	10285
R-HSA-1296071	Potassium Channels	1.00000000000382	3.82270659037437e-12	100	0	0	29	10285
R-HSA-5620912	Anchoring of the basal body to the plasma membrane	1.00000000000382	3.82270659037437e-12	100	0	0	29	10285
R-HSA-373076	Class A/1 (Rhodopsin-like receptors)	1.00000000000423	4.22538421611298e-12	322	0	0	29	10285
R-HSA-167021	PLC-gamma1 signalling	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-5663213	RHO GTPases Activate WASPs and WAVEs	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-452723	Transcriptional regulation of pluripotent stem cells	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-445355	Smooth Muscle Contraction	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-176033	Interactions of Vpr with host cellular proteins	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-6806003	Regulation of TP53 Expression and Degradation	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-532668	N-glycan trimming in the ER and Calnexin/Calreticulin cycle	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-76046	RNA Polymerase III Transcription Initiation	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-177243	Interactions of Rev with host cellular proteins	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-936440	Negative regulators of RIG-I/MDA5 signaling	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-212718	EGFR interacts with phospholipase C-gamma	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-432720	Lysosome Vesicle Biogenesis	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-2514856	The phototransduction cascade	1.00000000000431	4.31306035756833e-12	36	0	0	29	10285
R-HSA-73854	RNA Polymerase I Promoter Clearance	1.00000000000435	4.34572647190673e-12	110	0	0	29	10285
R-HSA-8856688	Golgi-to-ER retrograde transport	1.00000000000435	4.34572647190673e-12	110	0	0	29	10285
R-HSA-2990846	SUMOylation	1.00000000000435	4.34572647190673e-12	110	0	0	29	10285
R-HSA-2559582	Senescence-Associated Secretory Phenotype (SASP)	1.00000000000435	4.34572647190673e-12	110	0	0	29	10285
R-HSA-5250941	Negative epigenetic regulation of rRNA expression	1.00000000000435	4.34572647190673e-12	110	0	0	29	10285
R-HSA-194441	Metabolism of non-coding RNA	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-72695	Formation of the ternary complex, and subsequently, the 43S complex	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-180534	Vpu mediated degradation of CD4	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-191859	snRNP Assembly	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-72165	mRNA Splicing - Minor Pathway	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-75153	Apoptotic execution  phase	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-6806667	Metabolism of fat-soluble vitamins	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-349425	Autodegradation of the E3 ubiquitin ligase COP1	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-5620920	Cargo trafficking to the periciliary membrane	1.00000000000626	6.26091383087538e-12	53	0	0	29	10285
R-HSA-446219	Synthesis of substrates in N-glycan biosythesis	1.00000000000751	7.51077753912429e-12	63	0	0	29	10285
R-HSA-73728	RNA Polymerase I Promoter Opening	1.00000000000751	7.51077753912429e-12	63	0	0	29	10285
R-HSA-72662	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	1.00000000000751	7.51077753912429e-12	63	0	0	29	10285
R-HSA-1226099	Signaling by FGFR in disease	1.00000000000751	7.51077753912429e-12	63	0	0	29	10285
R-HSA-75105	Fatty Acyl-CoA Biosynthesis	1.00000000000757	7.5736572560077e-12	55	0	0	29	10285
R-HSA-1655829	Regulation of cholesterol biosynthesis by SREBP (SREBF)	1.00000000000757	7.5736572560077e-12	55	0	0	29	10285
R-HSA-180585	Vif-mediated degradation of APOBEC3G	1.00000000000757	7.5736572560077e-12	55	0	0	29	10285
R-HSA-163282	Mitochondrial transcription initiation	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-173599	Formation of the active cofactor, UDP-glucuronate	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-73927	Depurination	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-3311021	SMAD4 MH2 Domain Mutants in Cancer	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5339700	TCF7L2 mutants don't bind CTBP	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-77305	Beta oxidation of palmitoyl-CoA to myristoyl-CoA	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-1234162	Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-198745	Signalling to STAT3	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-444411	Rhesus glycoproteins mediate ammonium transport.	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5250992	Toxicity of botulinum toxin type E (BoNT/E)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-350864	Regulation of thyroid hormone activity	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-110331	Cleavage of the damaged purine	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-8849472	PTK6 Down-Regulation	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-73843	5-Phosphoribose 1-diphosphate biosynthesis	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-165181	Inhibition of TSC complex formation by PKB	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-3359463	Defective CUBN causes hereditary megaloblastic anemia 1	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-191647	c-src mediated regulation of Cx43 function and closure of gap junctions	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-427589	Type II Na+/Pi cotransporters	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-2395516	Electron transport from NADPH to Ferredoxin	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-180897	Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5653890	Lactose synthesis	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-77285	Beta oxidation of myristoyl-CoA to lauroyl-CoA	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-380615	Serotonin clearance from the synaptic cleft	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-111446	Activation of BIM and translocation to mitochondria	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-162699	Synthesis of dolichyl-phosphate mannose	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-3359462	Defective AMN causes hereditary megaloblastic anemia 1	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5688031	Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-191650	Regulation of gap junction activity	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-964827	Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-1368071	NR1D1 (REV-ERBA) represses gene expression	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-193681	Ceramide signalling	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5602680	MyD88 deficiency (TLR5)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-6806664	Metabolism of vitamin K	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5635851	GLI proteins bind promoters of Hh responsive genes to promote transcription	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-379397	Enzymatic degradation of dopamine by COMT	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-190374	FGFR1c and Klotho ligand binding and activation	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5658034	HHAT G278V abrogates palmitoylation of Hh-Np	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-111458	Formation of apoptosome	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-1299308	Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5624958	ARL13B-mediated ciliary trafficking of INPP5E	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-1307965	betaKlotho-mediated ligand binding	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-1299503	TWIK related potassium channel (TREK)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-175567	Integration of viral DNA into host genomic DNA	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-844615	The AIM2 inflammasome	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-351200	Interconversion of polyamines	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-977442	GABA A (rho) receptor activation	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-3296197	Hydroxycarboxylic acid-binding receptors	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-8853336	Signaling by plasma membrane FGFR1 fusions	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-190827	Transport of connexins along the secretory pathway	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-428359	Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5357572	Lysosomal glycogen catabolism	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-392023	Adrenaline signalling through Alpha-2 adrenergic receptor	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-3304347	Loss of Function of SMAD4 in Cancer	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-2892245	POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-352238	Breakdown of the nuclear lamina	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-1296067	Potassium transport channels	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-190704	Oligomerization of connexins into connexons	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-110330	Recognition and association of DNA glycosylase with site containing an affected purine	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-3249367	STAT6-mediated induction of chemokines	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-139910	Activation of BMF and translocation to mitochondria	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5627083	RHO GTPases regulate CFTR trafficking	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5250989	Toxicity of botulinum toxin type G (BoNT/G)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-964975	Vitamins B6 activation to pyridoxal phosphate	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-1483248	Synthesis of PIPs at the ER membrane	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-880009	Interconversion of 2-oxoglutarate and 2-hydroxyglutarate	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-265473	Trafficking of dietary sterols	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5250958	Toxicity of botulinum toxin type B (BoNT/B)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-77108	Utilization of Ketone Bodies	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-177539	Autointegration results in viral DNA circles	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-8875791	MET activates STAT3	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5602571	TRAF3 deficiency - HSE	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-844455	The NLRP1 inflammasome	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-217271	FMO oxidises nucleophiles	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-170145	Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-379398	Enzymatic degradation of Dopamine by monoamine oxidase	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-5250971	Toxicity of botulinum toxin type C (BoNT/C)	1.00000000000776	7.76177329972087e-12	3	0	0	29	10285
R-HSA-211733	Regulation of activated PAK-2p34 by proteasome mediated degradation	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-171306	Packaging Of Telomere Ends	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-112310	Neurotransmitter Release Cycle	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-1461973	Defensins	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-397795	G-protein beta:gamma signalling	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-1236978	Cross-presentation of soluble exogenous antigens (endosomes)	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-1793185	Chondroitin sulfate/dermatan sulfate metabolism	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-383280	Nuclear Receptor transcription pathway	1.00000000000789	7.8880985229719e-12	51	0	0	29	10285
R-HSA-72163	mRNA Splicing - Major Pathway	1.0000000000082	8.19972504544993e-12	187	0	0	29	10285
R-HSA-3247509	Chromatin modifying enzymes	1.00000000000848	8.48392545399292e-12	279	0	0	29	10285
R-HSA-4839726	Chromatin organization	1.00000000000848	8.48392545399292e-12	279	0	0	29	10285
R-HSA-69278	Cell Cycle, Mitotic	1.00000000000858	8.57853886566819e-12	514	0	0	29	10285
R-HSA-1852241	Organelle biogenesis and maintenance	1.0000000000096	9.60010417553172e-12	340	0	0	29	10285
R-HSA-2691232	Constitutive Signaling by NOTCH1 HD Domain Mutants	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-69183	Processive synthesis on the lagging strand	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-193807	Synthesis of bile acids and bile salts via 27-hydroxycholesterol	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-2046104	alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-111447	Activation of BAD and translocation to mitochondria	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-2046106	alpha-linolenic acid (ALA) metabolism	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-8875360	InlB-mediated entry of Listeria monocytogenes into host cell	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-3371568	Attenuation phase	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5358747	S33 mutants of beta-catenin aren't phosphorylated	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-170670	Adenylate cyclase inhibitory pathway	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-430039	mRNA decay by 5' to 3' exoribonuclease	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-997269	Inhibition of adenylate cyclase pathway	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5358752	T41 mutants of beta-catenin aren't phosphorylated	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5358508	Mismatch Repair	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-211935	Fatty acids	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5654228	Phospholipase C-mediated cascade; FGFR4	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-3772470	Negative regulation of TCF-dependent signaling by WNT ligand antagonists	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-4419969	Depolymerisation of the Nuclear Lamina	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-156581	Methylation	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-399955	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5358751	S45 mutants of beta-catenin aren't phosphorylated	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5358749	S37 mutants of beta-catenin aren't phosphorylated	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-69298	Association of licensing factors with the pre-replicative complex	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-205043	NRIF signals cell death from the nucleus	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-68884	Mitotic Telophase/Cytokinesis	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5099900	WNT5A-dependent internalization of FZD4	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-4839743	phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-3134975	Regulation of innate immune responses to cytosolic DNA	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-391903	Eicosanoid ligand-binding receptors	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-3322077	Glycogen synthesis	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5339716	Misspliced GSK3beta mutants stabilize beta-catenin	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-975577	N-Glycan antennae elongation	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-5682910	LGI-ADAM interactions	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-2691230	Signaling by NOTCH1 HD Domain Mutants in Cancer	1.0000000000101	1.00988936861304e-11	15	0	0	29	10285
R-HSA-535734	Fatty acid, triacylglycerol, and ketone body metabolism	1.00000000001113	1.11287827288546e-11	253	0	0	29	10285
R-HSA-425366	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	1.00000000001274	1.2743811625373e-11	106	0	0	29	10285
R-HSA-156580	Phase II conjugation	1.00000000001274	1.2743811625373e-11	106	0	0	29	10285
R-HSA-5578749	Transcriptional regulation by small RNAs	1.00000000001274	1.2743811625373e-11	106	0	0	29	10285
R-HSA-388396	GPCR downstream signaling	1.00000000001277	1.27675661587781e-11	974	0	0	29	10285
R-HSA-166054	Activated TLR4 signalling	1.0000000000133	1.32989809192317e-11	115	0	0	29	10285
R-HSA-73923	Lipid digestion, mobilization, and transport	1.0000000000133	1.32989809192317e-11	115	0	0	29	10285
R-HSA-6782135	Dual incision in TC-NER	1.0000000000163	1.62967805671486e-11	66	0	0	29	10285
R-HSA-72306	tRNA processing	1.00000000001686	1.68646138396492e-11	109	0	0	29	10285
R-HSA-211945	Phase 1 - Functionalization of compounds	1.00000000001686	1.68646138396492e-11	109	0	0	29	10285
R-HSA-73886	Chromosome Maintenance	1.00000000001686	1.68646138396492e-11	109	0	0	29	10285
R-HSA-69306	DNA Replication	1.00000000001686	1.68646138396492e-11	109	0	0	29	10285
R-HSA-1640170	Cell Cycle	1.000000000017	1.69956875640278e-11	621	0	0	29	10285
R-HSA-167162	RNA Polymerase II HIV Promoter Escape	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-73779	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-8948216	Collagen chain trimerization	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-76042	RNA Polymerase II Transcription Initiation And Promoter Clearance	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-1912422	Pre-NOTCH Expression and Processing	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-5576892	Phase 0 - rapid depolarisation	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-75953	RNA Polymerase II Transcription Initiation	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-1483249	Inositol phosphate metabolism	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-112043	PLC beta mediated events	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-167161	HIV Transcription Initiation	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-73776	RNA Polymerase II Promoter Escape	1.0000000000215	2.14996677949695e-11	47	0	0	29	10285
R-HSA-2559583	Cellular Senescence	1.00000000002493	2.49309197380133e-11	196	0	0	29	10285