Gene Ontology Enrichment Results

Homer de novo Motif Enrichment Results
Known Motif Enrichment Results

Text file version of complete results (i.e. open with Excel)

biological process: Functional groupings of proteins (Gene Ontology)

molecular function: Mechanistic actions of proteins (Gene Ontology)

cellular component: Protein localization (Gene Ontology)

chromosome location: Genes with similar chromosome localization (NCBI Gene)

KEGG pathways: Groups of proteins in the same pathways (KEGG)

protein interactions: "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" (NCBI Gene)

interpro domains: Proteins with similar domains and features (Interpro)

pfam domains: Proteins with similar domains and features (Pfam)

smart domains: Proteins with similar domains and features (SMART)

gene3d domains: Proteins with similar domains and features (Gene3D)

prosite domains: Proteins with similar domains and features (Prosite)

prints domains: Proteins with similar domains and features (PRINTS)

MSigDB lists: "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." (MSigDB)

BIOCYC pathways: Groups of proteins in the same pathways (BIOCYC)

COSMIC cancer mutations: Genes mutated in similar cancers (COSMIC)

GWAS genes: Genes mutated in similar diseases (GWAS Catalog)

Lipid Maps pathways: Groups of proteins in the same lipid pathways (Lipid Maps/Biosystems)

Pathway Interaction DB: Groups of proteins in the same pathways (Pathway Interaction Database)

REACTOME pathways: Groups of proteins in the same pathways (REACTOME)

SMPDB pathways: Groups of proteins in the same pathways (SMPDB)

WikiPathways: Groups of proteins in the same pathways (Wikipathways)

Enriched Categories

P-value	ln(P)	Term	GO Tree	GO ID	# of Genes in Term	# of Target Genes in Term	# of Total Genes	# of Target Genes	Common Genes
1.477e-14	-31.85	Burkitt_lymphoma	COSMIC cancer mutations	Burkitt_lymphoma	2119	29	16828	49	SLC8A1,DOCK4,ZFAND3,SLC9A9,SSH2,ZSWIM6,TBC1D22A,FRMD4A,ITPR2,ARHGAP26,ELMO1,DIP2B,KCNQ3,MED13L,MAML2,SYNDIG1,MAP4K4,ST6GAL1,ST6GALNAC3,ABCC4,PLXDC2,ANKRD44,PTPRJ,ATP8B4,ZFHX3,DSCAM,GNAQ,SORL1,CHST11
1.477e-14	-31.85	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma	2119	29	16828	49	CHST11,SORL1,GNAQ,ATP8B4,DSCAM,ZFHX3,ST6GALNAC3,ABCC4,PLXDC2,PTPRJ,ANKRD44,SYNDIG1,ST6GAL1,MAP4K4,MED13L,MAML2,KCNQ3,DIP2B,FRMD4A,ITPR2,ELMO1,ARHGAP26,SSH2,ZSWIM6,TBC1D22A,ZFAND3,SLC9A9,SLC8A1,DOCK4
1.218e-11	-25.13	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV	2531	28	16828	49	ELMO1,ARHGAP26,ITPR2,FRMD4A,TBC1D22A,ZBTB20,SLC9A9,ZFAND3,EPB41L2,SFMBT2,SLC8A1,MAML2,TCF12,KCNQ3,QKI,DIP2B,ZFHX3,DSCAM,ATP8B4,PTPRJ,ANKRD44,PLXDC2,ABCC4,ST6GALNAC3,MAP4K4,SYNDIG1,SORL1,GNAQ
2.876e-11	-24.27	blood_vessel	COSMIC cancer mutations	blood_vessel	2211	26	16828	49	PTPRJ,PLXDC2,ZFHX3,DSCAM,ATP8B4,SYNDIG1,ARHGAP24,PICALM,CHST11,GNAQ,SORL1,ADAM28,UBE2E2,TBC1D22A,ZSWIM6,ARHGAP26,ELMO1,ITPR2,FRMD4A,SFMBT2,SLC9A9,MAML2,MED13L,TCF12,DIP2B,KCNQ3
3.132e-11	-24.19	mantle_cell_lymphoma	COSMIC cancer mutations	mantle_cell_lymphoma	2849	29	16828	49	NAV3,GNAQ,UBE2E2,APBB1IP,SORL1,PLXDC2,ANKRD44,ST6GALNAC3,ATP8B4,DSCAM,ZFHX3,MAP4K4,ARHGAP24,MAML2,MAML3,DIP2B,KCNQ3,ZSWIM6,TBC1D22A,SSH2,ARHGAP26,ELMO1,MEF2A,FRMD4A,ITPR2,SLC8A1,SFMBT2,ZFAND3,SLC9A9
3.886e-11	-23.97	brainstem	COSMIC cancer mutations	brainstem	3102	30	16828	49	SYNDIG1,MAP4K4,ST6GALNAC3,ABCC4,PLXDC2,PTPRJ,ANKRD44,ATP8B4,DSCAM,ZFHX3,GNAQ,UBE2E2,SORL1,SLC8A1,SFMBT2,EPB41L2,ZFAND3,SLC9A9,ZBTB20,TBC1D22A,FRMD4A,ITPR2,ARHGAP26,ELMO1,DIP2B,MAML3,QKI,KCNQ3,TCF12,MAML2
8.233e-11	-23.22	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma	2737	28	16828	49	KCNQ3,DIP2B,MAML3,MAML2,SLC9A9,SFMBT2,SLC8A1,ITPR2,FRMD4A,MEF2A,ELMO1,ARHGAP26,SSH2,TBC1D22A,ZSWIM6,SORL1,APBB1IP,UBE2E2,GNAQ,NAV3,ARHGAP24,MAP4K4,ZFHX3,DSCAM,ATP8B4,ST6GALNAC3,ANKRD44,PLXDC2
1.746e-10	-22.47	angiosarcoma	COSMIC cancer mutations	angiosarcoma	2192	25	16828	49	UBE2E2,SORL1,ADAM28,CHST11,SYNDIG1,PICALM,ARHGAP24,PLXDC2,PTPRJ,ATP8B4,ZFHX3,DSCAM,DIP2B,KCNQ3,MED13L,MAML2,TCF12,SFMBT2,SLC9A9,ZSWIM6,TBC1D22A,ARHGAP26,ELMO1,FRMD4A,ITPR2
1.746e-10	-22.47	soft_tissue-blood_vessel-angiosarcoma	COSMIC cancer mutations	soft_tissue-blood_vessel-angiosarcoma	2192	25	16828	49	ITPR2,FRMD4A,ARHGAP26,ELMO1,TBC1D22A,ZSWIM6,SLC9A9,SFMBT2,TCF12,MAML2,MED13L,KCNQ3,DIP2B,ZFHX3,DSCAM,ATP8B4,PTPRJ,PLXDC2,ARHGAP24,PICALM,SYNDIG1,CHST11,SORL1,ADAM28,UBE2E2
6.230e-10	-21.20	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma	7205	42	16828	49	MED13L,MAML2,TCF12,MAML3,HDAC9,DIP2B,DOCK8,QKI,KCNQ3,ZSWIM6,TBC1D22A,SSH2,ARHGAP26,ELMO1,FRMD4A,ITPR2,DOCK4,EPB41L2,SLC8A1,SFMBT2,ZFAND3,ZBTB20,SLC9A9,NAV3,CHST11,GNAQ,UBE2E2,APBB1IP,SORL1,ADAM28,PLXDC2,PTPRJ,ANKRD44,ST6GALNAC3,ABCC4,ATP8B4,DSCAM,ZFHX3,SYNDIG1,MAP4K4,PICALM,ARHGAP22
1.050e-08	-18.37	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma	3608	29	16828	49	SORL1,APBB1IP,UBE2E2,GNAQ,NAV3,CHST11,SYNDIG1,ZFHX3,DSCAM,ATP8B4,ANKRD44,PLXDC2,ABCC4,ST6GALNAC3,KCNQ3,QKI,DIP2B,MEF2C,MAML2,MED13L,SLC9A9,ZFAND3,SLC8A1,ELMO1,ITPR2,FRMD4A,TBC1D22A,ZSWIM6,SSH2
1.793e-08	-17.84	acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	QKI,UBE2E2,KCNQ3,DIP2B,GNAQ,CHST11,MAML2,SLC9A9,SLC8A1,FRMD4A,ATP8B4,ZFHX3,ITPR2,DSCAM,ELMO1,ARHGAP26,ST6GALNAC3,PLXDC2,TBC1D22A
1.793e-08	-17.84	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related	1523	19	16828	49	TBC1D22A,PLXDC2,ST6GALNAC3,ELMO1,ARHGAP26,DSCAM,ITPR2,ZFHX3,ATP8B4,FRMD4A,SLC8A1,SLC9A9,MAML2,CHST11,GNAQ,DIP2B,KCNQ3,UBE2E2,QKI
3.218e-08	-17.25	soft_tissue	COSMIC cancer mutations	soft_tissue	5828	36	16828	49	SFMBT2,SLC8A1,EPB41L2,DOCK4,SLC9A9,ZFAND3,TBC1D22A,ZSWIM6,ITPR2,FRMD4A,MEF2A,ARHGAP26,ELMO1,DIP2B,HDAC9,MAML3,KCNQ3,DOCK8,TCF12,MAML2,MED13L,ARHGAP24,PICALM,MAP4K4,SYNDIG1,ABCC4,PTPRJ,PLXDC2,DSCAM,ZFHX3,ATP8B4,GNAQ,ADAM28,SORL1,UBE2E2,CHST11
3.828e-08	-17.08	central_nervous_system-brain-glioma-astrocytoma_Grade_III	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_III	1419	18	16828	49	ELMO1,ARHGAP26,DSCAM,ZFHX3,FRMD4A,PTPRJ,ZSWIM6,PLXDC2,ABCC4,ST6GALNAC3,SFMBT2,PICALM,MAML2,MED13L,KCNQ3,ADAM28,UBE2E2,GNAQ
4.276e-08	-16.97	acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	49	SLC9A9,ZBTB20,ZFAND3,SLC8A1,EPB41L2,ITPR2,FRMD4A,ARHGAP26,ELMO1,TBC1D22A,ZSWIM6,HDAC9,MEF2C,TCF12,MAML2,MED13L,PICALM,MAP4K4,SYNDIG1,DSCAM,ATP8B4,ABCC4,ST6GALNAC3,PTPRJ,ANKRD44,PLXDC2,SORL1,GNAQ,NAV3
4.276e-08	-16.97	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia	3828	29	16828	49	HDAC9,MED13L,MAML2,TCF12,MEF2C,EPB41L2,SLC8A1,ZFAND3,ZBTB20,SLC9A9,ZSWIM6,TBC1D22A,ARHGAP26,ELMO1,FRMD4A,ITPR2,GNAQ,SORL1,NAV3,SYNDIG1,MAP4K4,PICALM,PLXDC2,ANKRD44,PTPRJ,ST6GALNAC3,ABCC4,ATP8B4,DSCAM
5.023e-08	-16.81	prostate-carcinoma	COSMIC cancer mutations	prostate-carcinoma	9000	44	16828	49	SSH2,TBC1D22A,ZSWIM6,ITPR2,FRMD4A,MEF2A,ARHGAP26,ELMO1,SFMBT2,SLC8A1,EPB41L2,SLC9A9,ZBTB20,ZFAND3,TCF12,MAML2,MED13L,MEF2C,DIP2B,HDAC9,MAML3,KCNQ3,QKI,DOCK8,ABCC4,ST6GALNAC3,PTPRJ,ANKRD44,PLXDC2,DSCAM,ZFHX3,ATP8B4,ARHGAP22,PICALM,ARHGAP24,MAP4K4,SYNDIG1,CHST11,NAV3,GNAQ,SORL1,APBB1IP,UBE2E2,FCHSD2
5.785e-08	-16.67	bone	COSMIC cancer mutations	bone	8157	42	16828	49	GNAQ,FCHSD2,ADAM28,SORL1,APBB1IP,UBE2E2,HS3ST4,NAV3,CHST11,MAP4K4,SYNDIG1,PTPRJ,ANKRD44,ABCC4,ST6GALNAC3,DSCAM,ZFHX3,ATP8B4,HDAC9,MAML3,DIP2B,DOCK8,KCNQ3,QKI,MAML2,MED13L,TCF12,MEF2C,DOCK4,EPB41L2,SFMBT2,SLC8A1,ZBTB20,SLC9A9,ZFAND3,TBC1D22A,SSH2,MEF2A,ELMO1,ARHGAP26,ITPR2,FRMD4A
1.394e-07	-15.79	astrocytoma_Grade_III	COSMIC cancer mutations	astrocytoma_Grade_III	1544	18	16828	49	GNAQ,UBE2E2,ADAM28,KCNQ3,MED13L,MAML2,PICALM,SFMBT2,ZSWIM6,PLXDC2,PTPRJ,ST6GALNAC3,ABCC4,ARHGAP26,ELMO1,FRMD4A,DSCAM,ZFHX3
1.683e-07	-15.60	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma	1946	20	16828	49	HDAC9,GNAQ,DOCK8,KCNQ3,ADAM28,SORL1,UBE2E2,APBB1IP,MAML2,NAV3,MEF2C,MAP4K4,DOCK4,SFMBT2,ARHGAP22,ZBTB20,ANKRD44,PTPRJ,DSCAM,ITPR2
1.712e-07	-15.58	larynx	COSMIC cancer mutations	larynx	1948	20	16828	49	MEF2C,NAV3,MAML2,APBB1IP,UBE2E2,KCNQ3,SORL1,ADAM28,DOCK8,GNAQ,HDAC9,ITPR2,DSCAM,ANKRD44,PTPRJ,ZBTB20,ARHGAP22,SFMBT2,DOCK4,MAP4K4
2.123e-07	-15.37	stomach-adenocarcinoma	COSMIC cancer mutations	stomach-adenocarcinoma	4101	29	16828	49	GNAQ,APBB1IP,UBE2E2,ADAM28,SORL1,NAV3,CHST11,PICALM,ARHGAP22,PLXDC2,ANKRD44,PTPRJ,ATP8B4,DSCAM,ZFHX3,DOCK8,QKI,KCNQ3,MED13L,TCF12,SLC8A1,SFMBT2,ZFAND3,SLC9A9,TBC1D22A,SSH2,ELMO1,FRMD4A,ITPR2
2.803e-07	-15.09	diffuse_large_B_cell_lymphoma	COSMIC cancer mutations	diffuse_large_B_cell_lymphoma	4151	29	16828	49	ZFHX3,DSCAM,ATP8B4,ANKRD44,PLXDC2,ABCC4,ST6GALNAC3,SYNDIG1,NAV3,CHST11,SORL1,UBE2E2,APBB1IP,GNAQ,ELMO1,ITPR2,FRMD4A,TBC1D22A,ZSWIM6,SSH2,SLC9A9,ZFAND3,SLC8A1,MEF2C,MAML2,MED13L,KCNQ3,QKI,DIP2B
3.602e-07	-14.84	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	COSMIC cancer mutations	central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell	1117	15	16828	49	KCNQ3,QKI,GNAQ,MED13L,SLC9A9,DOCK4,ARHGAP22,SFMBT2,SLC8A1,ARHGAP26,DSCAM,FRMD4A,ATP8B4,ABCC4,ST6GALNAC3
4.557e-07	-14.60	cell junction	cellular component	GO:0030054	2224	19	19108	47	DSCAM,PTPRJ,GNAQ,ARHGAP26,FRMD4A,FCHSD2,SSH2,APBB1IP,QKI,MAP4K4,DISC1,ARHGAP24,ARHGAP22,SYNDIG1,KCNQ3,SLC8A1,EPB41L2,MEF2C,PICALM
7.980e-07	-14.04	HNRNPL (heterogeneous nuclear ribonucleoprotein L)	protein interactions	3191	1958	18	19454	50	SFMBT2,ABCC4,ZFHX3,PTPRJ,MEF2A,TBC1D22A,PLXDC2,DIP2B,MAML3,ZSWIM6,UBE2E2,QKI,ARHGAP24,ZFAND3,CHST11,DOCK4,ZBTB20,ANKRD44
1.475e-06	-13.43	cerebellum	COSMIC cancer mutations	cerebellum	769	12	16828	49	ELMO1,ITPR2,DSCAM,TBC1D22A,PLXDC2,SSH2,MAP4K4,SFMBT2,SLC8A1,MAML2,QKI,GNAQ
2.598e-06	-12.86	MEF2B (myocyte enhancer factor 2B)	protein interactions	100271849	11	3	19454	50	HDAC9,MEF2C,MEF2A
3.027e-06	-12.71	oesophagus-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-carcinoma-squamous_cell_carcinoma	6486	35	16828	49	MED13L,MAML2,DOCK8,KCNQ3,MAML3,HDAC9,DIP2B,MEF2A,FRMD4A,ITPR2,ZSWIM6,SSH2,ZBTB20,DOCK4,EPB41L2,SLC8A1,SFMBT2,NAV3,HS3ST4,FCHSD2,APBB1IP,DISC1,ADAM28,SORL1,GNAQ,ATP8B4,DSCAM,ZFHX3,ANKRD44,ST6GALNAC3,ABCC4,SYNDIG1,MAP4K4,ARHGAP24,ARHGAP22
3.596e-06	-12.54	stomach-carcinoma-intestinal_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-intestinal_adenocarcinoma	7225	37	16828	49	ABCC4,PTPRJ,ANKRD44,ZFHX3,DSCAM,ATP8B4,ARHGAP22,ARHGAP24,MAP4K4,ST6GAL1,SYNDIG1,HS3ST4,NAV3,SORL1,ADAM28,APBB1IP,FCHSD2,SSH2,TBC1D22A,ZSWIM6,ITPR2,FRMD4A,ELMO1,ARHGAP26,SFMBT2,SLC8A1,EPB41L2,DOCK4,ZBTB20,ZFAND3,MAML2,MED13L,HDAC9,MAML3,KCNQ3,QKI,DOCK8
3.596e-06	-12.54	intestinal_adenocarcinoma	COSMIC cancer mutations	intestinal_adenocarcinoma	7225	37	16828	49	APBB1IP,ADAM28,SORL1,FCHSD2,HS3ST4,NAV3,ARHGAP24,ARHGAP22,SYNDIG1,ST6GAL1,MAP4K4,ABCC4,PTPRJ,ANKRD44,ATP8B4,ZFHX3,DSCAM,MAML3,HDAC9,QKI,KCNQ3,DOCK8,MED13L,MAML2,SLC8A1,SFMBT2,DOCK4,EPB41L2,ZFAND3,ZBTB20,SSH2,ZSWIM6,TBC1D22A,FRMD4A,ITPR2,ARHGAP26,ELMO1
3.969e-06	-12.44	pancreas-carcinoid-endocrine_tumour	COSMIC cancer mutations	pancreas-carcinoid-endocrine_tumour	7250	37	16828	49	EPB41L2,SLC8A1,SFMBT2,ZFAND3,SLC9A9,ZSWIM6,TBC1D22A,SSH2,ARHGAP26,ELMO1,MEF2A,FRMD4A,ITPR2,MAML3,DIP2B,QKI,KCNQ3,MED13L,MAML2,SYNDIG1,MAP4K4,ST6GAL1,PICALM,PLXDC2,ANKRD44,PTPRJ,ST6GALNAC3,ABCC4,ATP8B4,ZFHX3,DSCAM,GNAQ,UBE2E2,APBB1IP,ADAM28,SORL1,CHST11
4.959e-06	-12.21	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm	7307	37	16828	49	SLC8A1,SFMBT2,EPB41L2,ZFAND3,SLC9A9,SSH2,ZSWIM6,TBC1D22A,FRMD4A,ITPR2,ELMO1,ARHGAP26,DIP2B,QKI,KCNQ3,DOCK8,MED13L,MAML2,PICALM,SYNDIG1,ST6GAL1,MAP4K4,ST6GALNAC3,ABCC4,PLXDC2,ANKRD44,PTPRJ,ATP8B4,DSCAM,ZFHX3,GNAQ,APBB1IP,UBE2E2,SORL1,ADAM28,CHST11,NAV3
5.326e-06	-12.14	prostate-carcinoma-adenocarcinoma	COSMIC cancer mutations	prostate-carcinoma-adenocarcinoma	12379	48	16828	49	CHST11,GNAQ,UBE2E2,SORL1,DISC1,ABCC4,PLXDC2,ANKRD44,PTPRJ,ATP8B4,DSCAM,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4,TCF12,MED13L,HDAC9,QKI,KCNQ3,SSH2,ZSWIM6,ARHGAP26,ELMO1,MEF2A,SLC8A1,SFMBT2,DOCK4,EPB41L2,ZFAND3,ZBTB20,HS3ST4,NAV3,APBB1IP,ADAM28,ST6GALNAC3,ZFHX3,PICALM,SYNDIG1,MAML2,MEF2C,DIP2B,MAML3,DOCK8,TBC1D22A,FRMD4A,ITPR2,SLC9A9
6.242e-06	-11.98	ovary-carcinoma-serous_carcinoma	COSMIC cancer mutations	ovary-carcinoma-serous_carcinoma	10710	45	16828	49	CHST11,SORL1,FCHSD2,GNAQ,ATP8B4,DSCAM,ABCC4,PLXDC2,ANKRD44,PTPRJ,ARHGAP24,ARHGAP22,MAP4K4,ST6GAL1,TCF12,MED13L,QKI,KCNQ3,HDAC9,ARHGAP26,ELMO1,MEF2A,SSH2,ZFAND3,ZBTB20,SLC8A1,SFMBT2,DOCK4,EPB41L2,NAV3,HS3ST4,APBB1IP,ADAM28,ZFHX3,ST6GALNAC3,PICALM,MEF2C,MAML2,DOCK8,DIP2B,MAML3,FRMD4A,ITPR2,TBC1D22A,SLC9A9
6.705e-06	-11.91	carcinoid-endocrine_tumour	COSMIC cancer mutations	carcinoid-endocrine_tumour	7752	38	16828	49	CHST11,ADAM28,SORL1,APBB1IP,UBE2E2,GNAQ,ZFHX3,DSCAM,ATP8B4,PTPRJ,ANKRD44,PLXDC2,ABCC4,ST6GALNAC3,MAP4K4,ST6GAL1,SYNDIG1,PICALM,MAML2,MED13L,DOCK8,KCNQ3,QKI,MAML3,DIP2B,MEF2A,ELMO1,ARHGAP26,ITPR2,FRMD4A,TBC1D22A,ZSWIM6,SSH2,SLC9A9,ZFAND3,EPB41L2,SFMBT2,SLC8A1
6.847e-06	-11.89	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	6023	33	16828	49	ADAM28,SORL1,APBB1IP,UBE2E2,GNAQ,NAV3,MAP4K4,DSCAM,ZFHX3,ATP8B4,PTPRJ,ANKRD44,ABCC4,DOCK8,KCNQ3,HDAC9,MAML3,DIP2B,MEF2C,MAML2,MED13L,TCF12,SLC9A9,ZBTB20,ZFAND3,DOCK4,EPB41L2,MEF2A,ELMO1,ITPR2,FRMD4A,TBC1D22A,SSH2
8.738e-06	-11.65	TWIST2 (twist family bHLH transcription factor 2)	protein interactions	117581	16	3	19454	50	TCF12,ZBTB20,MEF2C
8.906e-06	-11.63	anchoring junction	cellular component	GO:0070161	902	11	19108	47	ARHGAP22,FRMD4A,ARHGAP24,APBB1IP,SSH2,EPB41L2,SLC8A1,FCHSD2,PTPRJ,MAP4K4,ARHGAP26
1.041e-05	-11.47	lung-carcinoma-small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-small_cell_carcinoma	9908	43	16828	49	ZFAND3,DOCK4,EPB41L2,SLC8A1,SFMBT2,ELMO1,ARHGAP26,MEF2A,SSH2,QKI,KCNQ3,HDAC9,MED13L,TCF12,MAP4K4,ST6GAL1,ARHGAP24,ARHGAP22,ATP8B4,DSCAM,ANKRD44,PTPRJ,ABCC4,FCHSD2,UBE2E2,DISC1,SORL1,GNAQ,SLC9A9,FRMD4A,ITPR2,DOCK8,MAML3,DIP2B,MEF2C,MAML2,SYNDIG1,PICALM,ZFHX3,ST6GALNAC3,APBB1IP,ADAM28,NAV3
1.060e-05	-11.45	small_cell_carcinoma	COSMIC cancer mutations	small_cell_carcinoma	9913	43	16828	49	PTPRJ,ANKRD44,ST6GALNAC3,ABCC4,ATP8B4,ZFHX3,DSCAM,SYNDIG1,MAP4K4,ST6GAL1,PICALM,ARHGAP24,ARHGAP22,NAV3,GNAQ,FCHSD2,UBE2E2,APBB1IP,SORL1,ADAM28,DISC1,SSH2,ELMO1,ARHGAP26,MEF2A,FRMD4A,ITPR2,EPB41L2,DOCK4,SLC8A1,SFMBT2,ZFAND3,SLC9A9,MED13L,MAML2,TCF12,MEF2C,MAML3,HDAC9,DIP2B,DOCK8,QKI,KCNQ3
1.660e-05	-11.01	serous_carcinoma	COSMIC cancer mutations	serous_carcinoma	10987	45	16828	49	GNAQ,SORL1,FCHSD2,CHST11,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4,ABCC4,PLXDC2,PTPRJ,ANKRD44,ATP8B4,DSCAM,HDAC9,QKI,KCNQ3,TCF12,MED13L,SLC8A1,SFMBT2,EPB41L2,DOCK4,ZFAND3,ZBTB20,SSH2,ARHGAP26,ELMO1,MEF2A,APBB1IP,ADAM28,HS3ST4,NAV3,PICALM,ST6GALNAC3,ZFHX3,DIP2B,MAML3,DOCK8,MAML2,MEF2C,SLC9A9,TBC1D22A,FRMD4A,ITPR2
2.065e-05	-10.79	oesophagus-lower_third-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-adenocarcinoma	6302	33	16828	49	ARHGAP26,ELMO1,FRMD4A,ITPR2,EPB41L2,DOCK4,SLC8A1,SFMBT2,SLC9A9,ZBTB20,MED13L,MAML3,HDAC9,DIP2B,QKI,KCNQ3,PLXDC2,ANKRD44,PTPRJ,ST6GALNAC3,ABCC4,ATP8B4,ZFHX3,DSCAM,PICALM,HS3ST4,NAV3,CHST11,GNAQ,APBB1IP,ADAM28,DISC1,SORL1
2.139e-05	-10.75	MAML1-3	interpro domains	IPR046369	3	2	18521	50	MAML2,MAML3
2.139e-05	-10.75	Mastermind-like_N	interpro domains	IPR019082	3	2	18521	50	MAML2,MAML3
2.139e-05	-10.75	MAML_N_sf	interpro domains	IPR046370	3	2	18521	50	MAML3,MAML2
2.224e-05	-10.71	MamL-1	pfam domains	PF09596	3	2	17795	49	MAML3,MAML2
2.706e-05	-10.52	-	gene3d domains	6.10.250.970	3	2	14470	44	MAML2,MAML3
3.019e-05	-10.41	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	7434	36	16828	49	MEF2C,MED13L,MAML2,TCF12,DOCK8,QKI,KCNQ3,MAML3,HDAC9,DIP2B,ELMO1,MEF2A,FRMD4A,ITPR2,TBC1D22A,SSH2,ZFAND3,SLC9A9,ZBTB20,EPB41L2,DOCK4,SLC8A1,NAV3,FCHSD2,APBB1IP,UBE2E2,ADAM28,SORL1,GNAQ,ATP8B4,ZFHX3,DSCAM,PTPRJ,ANKRD44,ABCC4,MAP4K4
3.647e-05	-10.22	regulation of anatomical structure size	biological process	GO:0090066	498	8	18204	47	FCHSD2,DISC1,SLC8A1,PICALM,DSCAM,DOCK4,SSH2,DIP2B
3.969e-05	-10.13	upper_arm	COSMIC cancer mutations	upper_arm	582	9	16828	49	PTPRJ,PLXDC2,ST6GALNAC3,SSH2,ITPR2,ATP8B4,GNAQ,SLC9A9,ADAM28
3.994e-05	-10.13	MamL-1	smart domains	SM01275	3	2	9717	36	MAML3,MAML2
4.271e-05	-10.06	HJURP_C	interpro domains	IPR022102	4	2	18521	50	MEF2A,MEF2C
4.271e-05	-10.06	MADS_MEF2-like	interpro domains	IPR033896	4	2	18521	50	MEF2C,MEF2A
4.441e-05	-10.02	HJURP_C	pfam domains	PF12347	4	2	17795	49	MEF2C,MEF2A
4.999e-05	-9.90	Apelin signaling pathway	KEGG pathways	hsa04371	138	5	7161	22	MEF2C,ITPR2,SLC8A1,MEF2A,GNAQ
5.003e-05	-9.90	diffuse_adenocarcinoma	COSMIC cancer mutations	diffuse_adenocarcinoma	4383	26	16828	49	DSCAM,ZFHX3,ATP8B4,PTPRJ,PLXDC2,ST6GALNAC3,MAP4K4,SYNDIG1,ARHGAP22,CHST11,HS3ST4,SORL1,ADAM28,UBE2E2,GNAQ,ELMO1,ARHGAP26,ZFAND3,DOCK4,SFMBT2,SLC8A1,MED13L,DOCK8,KCNQ3,QKI,MAML3
5.003e-05	-9.90	stomach-carcinoma-diffuse_adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-diffuse_adenocarcinoma	4383	26	16828	49	MED13L,MAML3,KCNQ3,QKI,DOCK8,ARHGAP26,ELMO1,SFMBT2,SLC8A1,DOCK4,ZFAND3,HS3ST4,CHST11,GNAQ,ADAM28,SORL1,UBE2E2,ST6GALNAC3,PTPRJ,PLXDC2,DSCAM,ZFHX3,ATP8B4,ARHGAP22,MAP4K4,SYNDIG1
5.094e-05	-9.88	astrocytoma_Grade_I	COSMIC cancer mutations	astrocytoma_Grade_I	139	5	16828	49	QKI,SLC8A1,GNAQ,PLXDC2,TBC1D22A
5.335e-05	-9.84	lower_third	COSMIC cancer mutations	lower_third	7961	37	16828	49	ITPR2,FRMD4A,ELMO1,ARHGAP26,SSH2,ZBTB20,SLC9A9,SFMBT2,SLC8A1,EPB41L2,DOCK4,MEF2C,MED13L,KCNQ3,QKI,DIP2B,HDAC9,MAML3,ZFHX3,DSCAM,ATP8B4,ABCC4,ST6GALNAC3,PTPRJ,ANKRD44,PLXDC2,PICALM,ARHGAP24,SYNDIG1,CHST11,NAV3,HS3ST4,DISC1,ADAM28,SORL1,APBB1IP,GNAQ
5.474e-05	-9.81	GTPase regulator activity	molecular function	GO:0030695	491	8	18094	50	ELMO1,ARHGAP22,GNAQ,DOCK4,TBC1D22A,ARHGAP26,ARHGAP24,DOCK8
5.474e-05	-9.81	nucleoside-triphosphatase regulator activity	molecular function	GO:0060589	491	8	18094	50	ARHGAP22,ELMO1,DOCK8,ARHGAP24,ARHGAP26,TBC1D22A,GNAQ,DOCK4
5.695e-05	-9.77	VIRMA (vir like m6A methyltransferase associated)	protein interactions	25962	2914	19	19454	50	MAML3,SSH2,DISC1,CHST11,ANKRD44,ITPR2,ZBTB20,DOCK4,ZFHX3,ABCC4,ARHGAP26,SFMBT2,LDLRAD4,MED13L,MAML2,PTPRJ,PLXDC2,MAP4K4,DIP2B
7.106e-05	-9.55	TF_MADSbox_sf	interpro domains	IPR036879	5	2	18521	50	MEF2A,MEF2C
7.106e-05	-9.55	TF_MADSbox	interpro domains	IPR002100	5	2	18521	50	MEF2A,MEF2C
7.389e-05	-9.51	SRF-TF	pfam domains	PF00319	5	2	17795	49	MEF2C,MEF2A
7.699e-05	-9.47	focal adhesion	cellular component	GO:0005925	427	7	19108	47	EPB41L2,SSH2,APBB1IP,MAP4K4,ARHGAP26,ARHGAP22,ARHGAP24
7.798e-05	-9.46	lung-right_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_lower_lobe-carcinoma-adenocarcinoma	5692	30	16828	49	TCF12,MED13L,MAML2,DIP2B,MAML3,HDAC9,ITPR2,ELMO1,SSH2,TBC1D22A,SLC9A9,SLC8A1,EPB41L2,DOCK4,NAV3,HS3ST4,APBB1IP,SORL1,ADAM28,DISC1,FCHSD2,ATP8B4,ZFHX3,DSCAM,ABCC4,PLXDC2,ANKRD44,PTPRJ,MAP4K4,ST6GAL1
7.798e-05	-9.46	right_lower_lobe	COSMIC cancer mutations	right_lower_lobe	5692	30	16828	49	TBC1D22A,SSH2,ELMO1,ITPR2,DOCK4,EPB41L2,SLC8A1,SLC9A9,MED13L,MAML2,TCF12,MAML3,HDAC9,DIP2B,PLXDC2,ANKRD44,PTPRJ,ABCC4,ATP8B4,ZFHX3,DSCAM,MAP4K4,ST6GAL1,HS3ST4,NAV3,FCHSD2,APBB1IP,ADAM28,DISC1,SORL1
7.937e-05	-9.44	prostate	COSMIC cancer mutations	prostate	13883	49	16828	49	EPB41L2,DOCK4,SLC8A1,SFMBT2,ZFAND3,ZBTB20,ZSWIM6,SSH2,ARHGAP26,ELMO1,MEF2A,HDAC9,QKI,KCNQ3,MED13L,TCF12,MAP4K4,ST6GAL1,ARHGAP24,ARHGAP22,PLXDC2,ANKRD44,PTPRJ,ABCC4,ATP8B4,DSCAM,GNAQ,FCHSD2,UBE2E2,SORL1,DISC1,CHST11,SLC9A9,TBC1D22A,FRMD4A,ITPR2,MAML3,DIP2B,DOCK8,MAML2,MEF2C,SYNDIG1,PICALM,ST6GALNAC3,ZFHX3,APBB1IP,ADAM28,HS3ST4,NAV3
7.971e-05	-9.44	MADS_BOX_1	prosite domains	PS00350	5	2	12186	35	MEF2C,MEF2A
7.971e-05	-9.44	MADS_BOX_2	prosite domains	PS50066	5	2	12186	35	MEF2C,MEF2A
8.898e-05	-9.33	cell-substrate junction	cellular component	GO:0030055	437	7	19108	47	ARHGAP26,MAP4K4,EPB41L2,APBB1IP,SSH2,ARHGAP24,ARHGAP22
8.984e-05	-9.32	Transcription factor, MADS-box	gene3d domains	3.40.1810.10	5	2	14470	44	MEF2C,MEF2A
9.646e-05	-9.25	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	COSMIC cancer mutations	central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype	653	9	16828	49	GNAQ,SFMBT2,MAP4K4,ITPR2,DSCAM,ELMO1,SSH2,MAML2,PLXDC2
9.759e-05	-9.23	SHH_subtype	COSMIC cancer mutations	SHH_subtype	654	9	16828	49	GNAQ,SFMBT2,MAP4K4,SSH2,MAML2,PLXDC2,ITPR2,DSCAM,ELMO1
9.900e-05	-9.22	MADSDOMAIN	prints domains	PR00404	5	2	5227	17	MEF2A,MEF2C
1.017e-04	-9.19	GTPase activator activity	molecular function	GO:0005096	273	6	18094	50	DOCK4,GNAQ,TBC1D22A,ARHGAP26,ARHGAP24,ARHGAP22
1.027e-04	-9.18	kidney-carcinoma	COSMIC cancer mutations	kidney-carcinoma	3720	23	16828	49	QKI,HDAC9,MEF2C,TCF12,MED13L,MAML2,SLC9A9,FRMD4A,ITPR2,ARHGAP26,APBB1IP,UBE2E2,ADAM28,FCHSD2,GNAQ,NAV3,PICALM,ARHGAP24,ARHGAP22,MAP4K4,ST6GAL1,PTPRJ,ANKRD44
1.039e-04	-9.17	CDO in myogenesis	REACTOME pathways	R-HSA-375170	29	3	10285	33	MEF2C,TCF12,MEF2A
1.039e-04	-9.17	Myogenesis	REACTOME pathways	R-HSA-525793	29	3	10285	33	MEF2C,MEF2A,TCF12
1.073e-04	-9.14	neurogenesis	biological process	GO:0022008	1334	12	18204	47	KCNQ3,QKI,MEF2C,DSCAM,MAP4K4,PTPRJ,MEF2A,HDAC9,NAV3,PICALM,DISC1,ZSWIM6
1.106e-04	-9.11	cGMP-PKG signaling pathway	KEGG pathways	hsa04022	163	5	7161	22	ITPR2,MEF2C,SLC8A1,MEF2A,GNAQ
1.106e-04	-9.11	cGMP-PKG signaling pathway	KEGG pathways	ko04022	163	5	7161	22	SLC8A1,MEF2A,MEF2C,ITPR2,GNAQ
1.292e-04	-8.95	regulation of small GTPase mediated signal transduction	biological process	GO:0051056	306	6	18204	47	ARHGAP22,PICALM,ARHGAP24,ARHGAP26,DOCK8,MAP4K4
1.325e-04	-8.93	MADS	smart domains	SM00432	5	2	9717	36	MEF2C,MEF2A
1.328e-04	-8.93	regulation of multicellular organismal process	biological process	GO:0051239	3113	19	18204	47	DSCAM,DOCK4,MAP4K4,ZFHX3,QKI,MEF2C,GNAQ,DOCK8,SLC8A1,DISC1,LDLRAD4,SORL1,ZBTB20,DIP2B,MEF2A,PTPRJ,SYNDIG1,HDAC9,NAV3
1.359e-04	-8.90	positive regulation of transcription of Notch receptor target	biological process	GO:0007221	7	2	18204	47	MAML2,MAML3
1.435e-04	-8.85	regulation of locomotion	biological process	GO:0040012	1164	11	18204	47	HDAC9,ST6GAL1,PTPRJ,DOCK8,NAV3,MEF2C,DSCAM,DOCK4,LDLRAD4,SORL1,MAP4K4
1.476e-04	-8.82	ASCL1 (achaete-scute family bHLH transcription factor 1)	protein interactions	429	40	3	19454	50	MEF2C,MEF2A,TCF12
1.482e-04	-8.82	PH-like_dom_sf	interpro domains	IPR011993	431	7	18521	50	ARHGAP24,FRMD4A,ARHGAP26,EPB41L2,APBB1IP,ELMO1,ARHGAP22
1.610e-04	-8.73	bounding membrane of organelle	cellular component	GO:0098588	2198	15	19108	47	HS3ST4,SLC9A9,SYNDIG1,SORL1,CHST11,ST6GALNAC3,NAV3,ABCC4,ATP8B4,ST6GAL1,ITPR2,ARHGAP26,GNAQ,PTPRJ,LDLRAD4
1.777e-04	-8.64	skin-upper_arm-malignant_melanoma	COSMIC cancer mutations	skin-upper_arm-malignant_melanoma	553	8	16828	49	ADAM28,SLC9A9,SSH2,ST6GALNAC3,PTPRJ,PLXDC2,ITPR2,ATP8B4
1.786e-04	-8.63	positive regulation of hydrolase activity	biological process	GO:0051345	466	7	18204	47	ARHGAP24,DOCK8,TBC1D22A,GNAQ,MEF2C,ARHGAP22,MAP4K4
1.795e-04	-8.63	ZCWPW1 (zinc finger CW-type and PWWP domain containing 1)	protein interactions	55063	8	2	19454	50	PLXDC2,MEF2A
1.856e-04	-8.59	upper_leg	COSMIC cancer mutations	upper_leg	880	10	16828	49	DSCAM,ELMO1,SSH2,PTPRJ,PLXDC2,KCNQ3,ADAM28,DOCK8,GNAQ,SLC8A1
1.951e-04	-8.54	rhabdomyosarcoma	COSMIC cancer mutations	rhabdomyosarcoma	4150	24	16828	49	MAML2,MAML3,HDAC9,GNAQ,DIP2B,DOCK8,KCNQ3,SORL1,PTPRJ,ABCC4,ARHGAP26,ELMO1,MEF2A,ATP8B4,FRMD4A,ZFHX3,DSCAM,SYNDIG1,DOCK4,EPB41L2,MAP4K4,SLC8A1,SFMBT2,ZFAND3
1.998e-04	-8.52	biological regulation	biological process	GO:0065007	12501	43	18204	47	ELMO1,CHST11,GNAQ,MEF2C,MED13L,ITPR2,MAP4K4,ZFHX3,ATP8B4,HDAC9,DIP2B,SYNDIG1,ARHGAP26,SLC9A9,NAV3,FRMD4A,PICALM,ARHGAP22,SLC8A1,TCF12,MAML3,EPB41L2,MAML2,ST6GAL1,ARHGAP24,QKI,KCNQ3,DOCK8,DOCK4,DSCAM,SFMBT2,FCHSD2,MEF2A,PTPRJ,TBC1D22A,SSH2,UBE2E2,APBB1IP,ABCC4,LDLRAD4,ZBTB20,SORL1,DISC1
2.008e-04	-8.51	scalp	COSMIC cancer mutations	scalp	2110	16	16828	49	SORL1,KCNQ3,ADAM28,GNAQ,NAV3,CHST11,MED13L,SYNDIG1,SLC8A1,SFMBT2,ARHGAP22,ARHGAP26,ELMO1,ZFHX3,DSCAM,PTPRJ
2.060e-04	-8.49	positive regulation of GTPase activity	biological process	GO:0043547	211	5	18204	47	ARHGAP24,ARHGAP22,MAP4K4,TBC1D22A,DOCK8
2.071e-04	-8.48	lung-right_upper_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-right_upper_lobe-carcinoma-adenocarcinoma	10376	42	16828	49	PLXDC2,PTPRJ,ANKRD44,ST6GALNAC3,ABCC4,ATP8B4,ZFHX3,DSCAM,SYNDIG1,MAP4K4,ST6GAL1,ARHGAP24,PICALM,ARHGAP22,HS3ST4,NAV3,CHST11,FCHSD2,APBB1IP,UBE2E2,ADAM28,SORL1,DISC1,TBC1D22A,SSH2,ELMO1,ARHGAP26,FRMD4A,ITPR2,EPB41L2,DOCK4,SLC8A1,SFMBT2,SLC9A9,ZBTB20,MED13L,MEF2C,MAML3,HDAC9,DIP2B,DOCK8,KCNQ3
2.071e-04	-8.48	right_upper_lobe	COSMIC cancer mutations	right_upper_lobe	10376	42	16828	49	FCHSD2,SORL1,ADAM28,DISC1,UBE2E2,APBB1IP,HS3ST4,NAV3,CHST11,MAP4K4,ST6GAL1,SYNDIG1,ARHGAP22,ARHGAP24,PICALM,ANKRD44,PTPRJ,PLXDC2,ABCC4,ST6GALNAC3,DSCAM,ZFHX3,ATP8B4,HDAC9,MAML3,DIP2B,DOCK8,KCNQ3,MED13L,MEF2C,EPB41L2,DOCK4,SFMBT2,SLC8A1,SLC9A9,ZBTB20,TBC1D22A,SSH2,ARHGAP26,ELMO1,ITPR2,FRMD4A
2.101e-04	-8.47	MEF2C (myocyte enhancer factor 2C)	protein interactions	4208	45	3	19454	50	HDAC9,MEF2A,MEF2C
2.193e-04	-8.42	regulation of cellular component biogenesis	biological process	GO:0044087	1016	10	18204	47	SYNDIG1,PTPRJ,ARHGAP24,MEF2C,NAV3,SSH2,TBC1D22A,MAP4K4,FCHSD2,SORL1
2.443e-04	-8.32	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I	105	4	16828	49	TBC1D22A,PLXDC2,SLC8A1,QKI
2.496e-04	-8.30	lymph_node	COSMIC cancer mutations	lymph_node	1703	14	16828	49	MAML2,TCF12,NAV3,MEF2C,GNAQ,ZSWIM6,ELMO1,ITPR2,ZFHX3,DSCAM,ATP8B4,MAP4K4,ARHGAP24,ZFAND3
2.531e-04	-8.28	large_intestine-colon	COSMIC cancer mutations	large_intestine-colon	1291	12	16828	49	ATP8B4,ANKRD44,ZBTB20,MAP4K4,ARHGAP24,SFMBT2,NAV3,MEF2C,HS3ST4,MED13L,SORL1,KCNQ3
2.585e-04	-8.26	nervous system development	biological process	GO:0007399	2185	15	18204	47	QKI,KCNQ3,MEF2C,DSCAM,MAP4K4,HDAC9,DIP2B,MEF2A,ARHGAP26,PTPRJ,NAV3,PICALM,TCF12,ZSWIM6,DISC1
2.646e-04	-8.24	striated_muscle	COSMIC cancer mutations	striated_muscle	4228	24	16828	49	MAML2,DIP2B,HDAC9,MAML3,KCNQ3,DOCK8,FRMD4A,MEF2A,ELMO1,ARHGAP26,SFMBT2,SLC8A1,EPB41L2,DOCK4,ZFAND3,GNAQ,SORL1,ABCC4,PTPRJ,ZFHX3,DSCAM,ATP8B4,MAP4K4,SYNDIG1
2.722e-04	-8.21	large_intestine-caecum-carcinoma-adenocarcinoma	COSMIC cancer mutations	large_intestine-caecum-carcinoma-adenocarcinoma	14236	49	16828	49	SYNDIG1,PICALM,ZFHX3,ST6GALNAC3,APBB1IP,ADAM28,NAV3,HS3ST4,SLC9A9,FRMD4A,ITPR2,TBC1D22A,DOCK8,MAML3,DIP2B,MEF2C,MAML2,ST6GAL1,MAP4K4,ARHGAP24,ARHGAP22,ATP8B4,DSCAM,PLXDC2,PTPRJ,ANKRD44,ABCC4,FCHSD2,UBE2E2,DISC1,SORL1,GNAQ,CHST11,ZFAND3,ZBTB20,EPB41L2,DOCK4,SLC8A1,SFMBT2,ELMO1,ARHGAP26,MEF2A,ZSWIM6,SSH2,QKI,KCNQ3,HDAC9,MED13L,TCF12
2.755e-04	-8.20	regulation of cellular component size	biological process	GO:0032535	352	6	18204	47	SSH2,DIP2B,FCHSD2,DISC1,PICALM,DSCAM
2.837e-04	-8.17	caecum	COSMIC cancer mutations	caecum	14248	49	16828	49	PICALM,SYNDIG1,ZFHX3,ST6GALNAC3,APBB1IP,ADAM28,NAV3,HS3ST4,SLC9A9,FRMD4A,ITPR2,TBC1D22A,DOCK8,DIP2B,MAML3,MEF2C,MAML2,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4,ATP8B4,DSCAM,ABCC4,PLXDC2,ANKRD44,PTPRJ,UBE2E2,DISC1,SORL1,FCHSD2,GNAQ,CHST11,ZFAND3,ZBTB20,SLC8A1,SFMBT2,EPB41L2,DOCK4,ELMO1,ARHGAP26,MEF2A,SSH2,ZSWIM6,QKI,KCNQ3,HDAC9,TCF12,MED13L
2.925e-04	-8.14	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)	gene3d domains	2.30.29.30	431	7	14470	44	ARHGAP22,APBB1IP,EPB41L2,ARHGAP26,ELMO1,FRMD4A,ARHGAP24
2.935e-04	-8.13	lung-carcinoma	COSMIC cancer mutations	lung-carcinoma	4255	24	16828	49	ARHGAP22,ARHGAP24,PICALM,ST6GAL1,MAP4K4,ZFHX3,ANKRD44,PTPRJ,ADAM28,APBB1IP,UBE2E2,FCHSD2,GNAQ,NAV3,SLC9A9,ITPR2,FRMD4A,ARHGAP26,QKI,HDAC9,MEF2C,TCF12,MAML2,MED13L
2.971e-04	-8.12	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma	9263	39	16828	49	SORL1,ADAM28,UBE2E2,APBB1IP,FCHSD2,GNAQ,CHST11,NAV3,ARHGAP22,PICALM,ARHGAP24,MAP4K4,ST6GAL1,DSCAM,ZFHX3,ATP8B4,ST6GALNAC3,ANKRD44,PTPRJ,KCNQ3,QKI,DOCK8,DIP2B,HDAC9,MAML3,MEF2C,TCF12,MAML2,MED13L,SLC9A9,SFMBT2,SLC8A1,DOCK4,EPB41L2,ITPR2,FRMD4A,ARHGAP26,TBC1D22A,ZSWIM6
3.095e-04	-8.08	oesophagus-carcinoma	COSMIC cancer mutations	oesophagus-carcinoma	4269	24	16828	49	ST6GALNAC3,ABCC4,DSCAM,ZFHX3,SYNDIG1,MAP4K4,ST6GAL1,HS3ST4,CHST11,NAV3,SORL1,ADAM28,FRMD4A,ITPR2,ELMO1,MEF2A,SFMBT2,DOCK4,ZBTB20,MED13L,DIP2B,MAML3,HDAC9,DOCK8
3.099e-04	-8.08	CALD1 (caldesmon 1)	protein interactions	800	231	5	19454	50	DISC1,QKI,ITPR2,DOCK8,EPB41L2
3.134e-04	-8.07	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm	764	9	16828	49	UBE2E2,SORL1,ZFAND3,SLC9A9,ST6GALNAC3,MAML2,FRMD4A,DSCAM,ARHGAP26
3.356e-04	-8.00	Lima1 (LIM domain and actin binding 1)	protein interactions	65970	129	4	19454	50	ZBTB20,ITPR2,PICALM,SSH2
3.536e-04	-7.95	regulation of macrophage apoptotic process	biological process	GO:2000109	11	2	18204	47	MEF2C,ST6GAL1
3.647e-04	-7.92	lung-carcinoma-non_small_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-non_small_cell_carcinoma	5198	27	16828	49	FRMD4A,ITPR2,ARHGAP26,SSH2,SLC9A9,SLC8A1,MEF2C,TCF12,MED13L,MAML2,QKI,HDAC9,DSCAM,ZFHX3,PTPRJ,ANKRD44,ARHGAP24,PICALM,ARHGAP22,MAP4K4,ST6GAL1,NAV3,UBE2E2,APBB1IP,ADAM28,FCHSD2,GNAQ
3.647e-04	-7.92	non_small_cell_carcinoma	COSMIC cancer mutations	non_small_cell_carcinoma	5198	27	16828	49	GNAQ,FCHSD2,UBE2E2,APBB1IP,ADAM28,NAV3,MAP4K4,ST6GAL1,PICALM,ARHGAP24,ARHGAP22,ANKRD44,PTPRJ,DSCAM,ZFHX3,HDAC9,QKI,MED13L,MAML2,TCF12,MEF2C,SLC8A1,SLC9A9,SSH2,ARHGAP26,FRMD4A,ITPR2
3.815e-04	-7.87	DOCK3 (dedicator of cytokinesis 3)	protein interactions	1795	55	3	19454	50	ELMO1,HS3ST4,DOCK4
3.868e-04	-7.86	DOCKER_dom	interpro domains	IPR027357	11	2	18521	50	DOCK8,DOCK4
3.868e-04	-7.86	DOCK_C_lobe_A	interpro domains	IPR043161	11	2	18521	50	DOCK4,DOCK8
3.868e-04	-7.86	DOCK	interpro domains	IPR026791	11	2	18521	50	DOCK8,DOCK4
3.868e-04	-7.86	DOCKER_Lobe_B	interpro domains	IPR046770	11	2	18521	50	DOCK8,DOCK4
3.868e-04	-7.86	DOCKER_Lobe_C	interpro domains	IPR046773	11	2	18521	50	DOCK8,DOCK4
3.868e-04	-7.86	C2_DOCK-type_domain	interpro domains	IPR027007	11	2	18521	50	DOCK8,DOCK4
3.868e-04	-7.86	DOCKER_Lobe_A	interpro domains	IPR046769	11	2	18521	50	DOCK4,DOCK8
3.868e-04	-7.86	DOCK_C_lobe_C	interpro domains	IPR043162	11	2	18521	50	DOCK4,DOCK8
3.895e-04	-7.85	cell body	cellular component	GO:0044297	556	7	19108	47	DISC1,SLC8A1,PICALM,SORL1,DSCAM,SYNDIG1,DIP2B
4.021e-04	-7.82	DOCK-C2	pfam domains	PF14429	11	2	17795	49	DOCK8,DOCK4
4.021e-04	-7.82	DHR-2_Lobe_B	pfam domains	PF20422	11	2	17795	49	DOCK8,DOCK4
4.021e-04	-7.82	DHR-2_Lobe_A	pfam domains	PF06920	11	2	17795	49	DOCK4,DOCK8
4.021e-04	-7.82	DHR-2_Lobe_C	pfam domains	PF20421	11	2	17795	49	DOCK4,DOCK8
4.052e-04	-7.81	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-lower_third-carcinoma-squamous_cell_carcinoma	3507	21	16828	49	SFMBT2,ARHGAP24,EPB41L2,DOCK4,SYNDIG1,ZBTB20,SSH2,ZFHX3,DSCAM,FRMD4A,ATP8B4,ARHGAP26,DIP2B,HDAC9,MAML3,SORL1,ADAM28,KCNQ3,HS3ST4,MEF2C,NAV3
4.062e-04	-7.81	positive regulation of cell-matrix adhesion	biological process	GO:0001954	56	3	18204	47	DISC1,MAP4K4,PTPRJ
4.337e-04	-7.74	DOCKER	prosite domains	PS51651	11	2	12186	35	DOCK4,DOCK8
4.337e-04	-7.74	C2_DOCK	prosite domains	PS51650	11	2	12186	35	DOCK4,DOCK8
4.593e-04	-7.69	haematopoietic_neoplasm	COSMIC cancer mutations	haematopoietic_neoplasm	11082	43	16828	49	NAV3,CHST11,FCHSD2,UBE2E2,ADAM28,SORL1,GNAQ,ATP8B4,DSCAM,ZFHX3,PLXDC2,ANKRD44,PTPRJ,ST6GALNAC3,ABCC4,MAP4K4,ST6GAL1,ARHGAP24,PICALM,MEF2C,MED13L,MAML2,TCF12,DOCK8,QKI,KCNQ3,MAML3,HDAC9,DIP2B,ARHGAP26,ELMO1,MEF2A,FRMD4A,ITPR2,ZSWIM6,TBC1D22A,SSH2,ZFAND3,SLC9A9,EPB41L2,DOCK4,SLC8A1,SFMBT2
4.718e-04	-7.66	NOTCH1 Intracellular Domain Regulates Transcription	REACTOME pathways	R-HSA-2122947	48	3	10285	33	MAML2,HDAC9,MAML3
4.884e-04	-7.62	-	gene3d domains	1.20.58.740	11	2	14470	44	DOCK4,DOCK8
4.884e-04	-7.62	-	gene3d domains	1.25.40.410	11	2	14470	44	DOCK8,DOCK4
4.895e-04	-7.62	trunk	COSMIC cancer mutations	trunk	3554	21	16828	49	TCF12,MAML2,DIP2B,GNAQ,ADAM28,SORL1,DISC1,APBB1IP,DOCK8,FCHSD2,ABCC4,SSH2,PTPRJ,ANKRD44,DSCAM,ZFHX3,ATP8B4,ARHGAP26,SFMBT2,SLC8A1,SYNDIG1
4.949e-04	-7.61	SOX2 (SRY-box transcription factor 2)	protein interactions	6657	1342	11	19454	50	MEF2A,ITPR2,NAV3,FRMD4A,MED13L,ARHGAP26,ZFHX3,MEF2C,QKI,TCF12,PICALM
5.137e-04	-7.57	PLCG1 (phospholipase C gamma 1)	protein interactions	5335	258	5	19454	50	DISC1,PICALM,EPB41L2,PTPRJ,LDLRAD4
5.247e-04	-7.55	thyroid-carcinoma	COSMIC cancer mutations	thyroid-carcinoma	4126	23	16828	49	MEF2C,MED13L,DOCK8,HDAC9,FRMD4A,ITPR2,ARHGAP26,ELMO1,ZFAND3,SLC9A9,SLC8A1,SFMBT2,DOCK4,CHST11,NAV3,HS3ST4,SORL1,ZFHX3,DSCAM,PLXDC2,ANKRD44,PTPRJ,MAP4K4
5.287e-04	-7.55	oesophagus-carcinoma-adenocarcinoma	COSMIC cancer mutations	oesophagus-carcinoma-adenocarcinoma	13112	47	16828	49	DOCK4,EPB41L2,SFMBT2,SLC8A1,ZBTB20,ZFAND3,ZSWIM6,SSH2,ELMO1,ARHGAP26,HDAC9,KCNQ3,QKI,MED13L,TCF12,ST6GAL1,MAP4K4,ARHGAP22,ARHGAP24,PTPRJ,ANKRD44,PLXDC2,ABCC4,DSCAM,ATP8B4,GNAQ,SORL1,DISC1,UBE2E2,CHST11,SLC9A9,TBC1D22A,ITPR2,FRMD4A,MAML3,DIP2B,DOCK8,MAML2,MEF2C,SYNDIG1,PICALM,ST6GALNAC3,ZFHX3,ADAM28,APBB1IP,HS3ST4,NAV3
5.776e-04	-7.46	BORCS8-MEF2B (BORCS8-MEF2B readthrough)	protein interactions	4207	14	2	19454	50	MEF2A,MEF2C
5.821e-04	-7.45	ventricular cardiac muscle cell differentiation	biological process	GO:0055012	14	2	18204	47	MEF2C,MEF2A
6.018e-04	-7.42	dendrite morphogenesis	biological process	GO:0048813	64	3	18204	47	DSCAM,PICALM,MEF2A
6.523e-04	-7.34	MAML1 (mastermind like transcriptional coactivator 1)	protein interactions	9794	66	3	19454	50	MAML2,MAML3,HDAC9
6.604e-04	-7.32	pleura-mesothelioma	COSMIC cancer mutations	pleura-mesothelioma	4189	23	16828	49	GNAQ,ADAM28,UBE2E2,APBB1IP,FCHSD2,NAV3,ARHGAP22,PICALM,ARHGAP24,ST6GAL1,MAP4K4,ANKRD44,PTPRJ,HDAC9,QKI,TCF12,MAML2,MED13L,MEF2C,SLC9A9,ITPR2,FRMD4A,ARHGAP26
6.740e-04	-7.30	regulation of biological quality	biological process	GO:0065008	2936	17	18204	47	DISC1,PICALM,ARHGAP22,SLC8A1,SLC9A9,SSH2,DIP2B,SYNDIG1,PTPRJ,FCHSD2,ATP8B4,DOCK4,DSCAM,GNAQ,MEF2C,QKI,KCNQ3
6.811e-04	-7.29	skin-upper_leg-malignant_melanoma	COSMIC cancer mutations	skin-upper_leg-malignant_melanoma	850	9	16828	49	DSCAM,ELMO1,SSH2,PTPRJ,PLXDC2,KCNQ3,ADAM28,DOCK8,SLC8A1
7.118e-04	-7.25	MYOG (myogenin)	protein interactions	4656	68	3	19454	50	TCF12,MEF2C,MEF2A
7.156e-04	-7.24	system development	biological process	GO:0048731	3533	19	18204	47	HDAC9,ARHGAP26,PTPRJ,MEF2A,DIP2B,NAV3,PICALM,ARHGAP22,SLC8A1,ZSWIM6,TCF12,DISC1,ARHGAP24,QKI,CHST11,KCNQ3,MEF2C,DSCAM,MAP4K4
7.186e-04	-7.24	synapse	cellular component	GO:0045202	1473	11	19108	47	DISC1,SLC8A1,PICALM,MEF2C,SYNDIG1,ARHGAP22,KCNQ3,GNAQ,DSCAM,FCHSD2,QKI
7.188e-04	-7.24	RhoGAP_dom	interpro domains	IPR000198	65	3	18521	50	ARHGAP22,ARHGAP24,ARHGAP26
7.275e-04	-7.23	regulation of GTPase activity	biological process	GO:0043087	278	5	18204	47	ARHGAP24,ARHGAP22,TBC1D22A,DOCK8,MAP4K4
7.356e-04	-7.21	PH_domain	interpro domains	IPR001849	266	5	18521	50	ARHGAP26,ARHGAP24,ARHGAP22,APBB1IP,ELMO1
7.371e-04	-7.21	SRF and miRs in Smooth Muscle Differentiation and Proliferation	WikiPathways	WP1991	13	2	5310	17	MEF2A,MEF2C
7.601e-04	-7.18	RhoGAP	pfam domains	PF00620	65	3	17795	49	ARHGAP24,ARHGAP26,ARHGAP22
7.617e-04	-7.18	NOTCH2 intracellular domain regulates transcription	REACTOME pathways	R-HSA-2197563	13	2	10285	33	MAML2,MAML3
7.617e-04	-7.18	Notch-HLH transcription pathway	REACTOME pathways	R-HSA-350054	13	2	10285	33	MAML2,MAML3
7.634e-04	-7.18	regulation of cellular process	biological process	GO:0050794	11468	40	18204	47	DSCAM,DOCK4,SFMBT2,FCHSD2,ARHGAP24,QKI,ST6GAL1,KCNQ3,DOCK8,UBE2E2,APBB1IP,ZBTB20,SORL1,LDLRAD4,DISC1,PTPRJ,MEF2A,SSH2,TBC1D22A,MED13L,ITPR2,ZFHX3,MAP4K4,CHST11,ELMO1,GNAQ,MEF2C,PICALM,ARHGAP22,SLC8A1,TCF12,MAML2,EPB41L2,MAML3,HDAC9,SYNDIG1,ARHGAP26,DIP2B,FRMD4A,NAV3
7.916e-04	-7.14	face	COSMIC cancer mutations	face	2139	15	16828	49	ITPR2,DSCAM,ZFHX3,PTPRJ,ABCC4,SFMBT2,SLC8A1,ARHGAP24,PICALM,NAV3,MED13L,SORL1,ADAM28,KCNQ3,GNAQ
8.065e-04	-7.12	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia	10418	41	16828	49	FCHSD2,ADAM28,SORL1,UBE2E2,GNAQ,NAV3,ST6GAL1,MAP4K4,ARHGAP24,PICALM,DSCAM,ZFHX3,ATP8B4,PTPRJ,ANKRD44,PLXDC2,ABCC4,ST6GALNAC3,DOCK8,KCNQ3,QKI,HDAC9,MAML3,DIP2B,MEF2C,MAML2,MED13L,TCF12,SLC9A9,DOCK4,EPB41L2,SFMBT2,SLC8A1,MEF2A,ELMO1,ARHGAP26,ITPR2,FRMD4A,TBC1D22A,ZSWIM6,SSH2
8.065e-04	-7.12	acute_myeloid_leukaemia	COSMIC cancer mutations	acute_myeloid_leukaemia	10418	41	16828	49	DSCAM,ZFHX3,ATP8B4,ABCC4,ST6GALNAC3,PTPRJ,ANKRD44,PLXDC2,ARHGAP24,PICALM,MAP4K4,ST6GAL1,NAV3,SORL1,ADAM28,UBE2E2,FCHSD2,GNAQ,ITPR2,FRMD4A,MEF2A,ELMO1,ARHGAP26,SSH2,TBC1D22A,ZSWIM6,SLC9A9,SFMBT2,SLC8A1,EPB41L2,DOCK4,MEF2C,TCF12,MAML2,MED13L,KCNQ3,QKI,DOCK8,DIP2B,HDAC9,MAML3
8.235e-04	-7.10	Constitutive Signaling by NOTCH1 PEST Domain Mutants	REACTOME pathways	R-HSA-2644606	58	3	10285	33	MAML3,HDAC9,MAML2
8.235e-04	-7.10	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	REACTOME pathways	R-HSA-2894862	58	3	10285	33	HDAC9,MAML2,MAML3
8.235e-04	-7.10	Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	REACTOME pathways	R-HSA-2894858	58	3	10285	33	HDAC9,MAML2,MAML3
8.235e-04	-7.10	Signaling by NOTCH1 PEST Domain Mutants in Cancer	REACTOME pathways	R-HSA-2644602	58	3	10285	33	MAML2,HDAC9,MAML3
8.235e-04	-7.10	Signaling by NOTCH1 in Cancer	REACTOME pathways	R-HSA-2644603	58	3	10285	33	MAML3,MAML2,HDAC9
8.392e-04	-7.08	RHOGAP	prosite domains	PS50238	65	3	12186	35	ARHGAP22,ARHGAP24,ARHGAP26
8.491e-04	-7.07	cellular response to calcium ion	biological process	GO:0071277	72	3	18204	47	MEF2C,KCNQ3,MEF2A
8.590e-04	-7.06	NOTCH4 (notch receptor 4)	protein interactions	4855	17	2	19454	50	MAML3,MAML2
8.681e-04	-7.05	lymphoid_neoplasm	COSMIC cancer mutations	lymphoid_neoplasm	12233	45	16828	49	ARHGAP24,MAP4K4,ST6GAL1,ATP8B4,DSCAM,ABCC4,PLXDC2,PTPRJ,ANKRD44,UBE2E2,SORL1,GNAQ,CHST11,ZFAND3,ZBTB20,SLC8A1,SFMBT2,DOCK4,EPB41L2,ELMO1,ARHGAP26,MEF2A,SSH2,ZSWIM6,QKI,KCNQ3,HDAC9,TCF12,MED13L,PICALM,SYNDIG1,ZFHX3,ST6GALNAC3,APBB1IP,ADAM28,NAV3,SLC9A9,FRMD4A,ITPR2,TBC1D22A,DOCK8,DIP2B,MAML3,MEF2C,MAML2
9.104e-04	-7.00	regulation of cellular component organization	biological process	GO:0051128	2455	15	18204	47	MEF2C,ARHGAP24,MAP4K4,FCHSD2,DSCAM,NAV3,SSH2,TBC1D22A,SYNDIG1,PTPRJ,DIP2B,DISC1,SORL1,ARHGAP22,PICALM
9.140e-04	-7.00	embryonal	COSMIC cancer mutations	embryonal	2659	17	16828	49	MEF2A,ELMO1,ZFHX3,DSCAM,ATP8B4,PTPRJ,ABCC4,ZFAND3,DOCK4,SYNDIG1,SFMBT2,MAML2,DOCK8,KCNQ3,SORL1,DIP2B,GNAQ
9.140e-04	-7.00	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal	2659	17	16828	49	DIP2B,GNAQ,DOCK8,SORL1,KCNQ3,MAML2,DOCK4,SYNDIG1,SFMBT2,ZFAND3,PTPRJ,ABCC4,MEF2A,ELMO1,ZFHX3,DSCAM,ATP8B4
9.470e-04	-6.96	HDAC9 (histone deacetylase 9)	protein interactions	9734	75	3	19454	50	MEF2C,HDAC9,MEF2A
9.470e-04	-6.96	MEF2A (myocyte enhancer factor 2A)	protein interactions	4205	75	3	19454	50	HDAC9,MEF2A,MEF2C
9.479e-04	-6.96	cervix-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	cervix-carcinoma-squamous_cell_carcinoma	11789	44	16828	49	TCF12,MED13L,HDAC9,QKI,KCNQ3,SSH2,ZSWIM6,ELMO1,MEF2A,SLC8A1,SFMBT2,DOCK4,ZBTB20,CHST11,GNAQ,DISC1,SORL1,FCHSD2,ABCC4,PLXDC2,PTPRJ,ANKRD44,ATP8B4,DSCAM,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4,MAML2,MEF2C,DIP2B,MAML3,DOCK8,TBC1D22A,FRMD4A,ITPR2,SLC9A9,NAV3,APBB1IP,ADAM28,ST6GALNAC3,ZFHX3,PICALM,SYNDIG1
9.587e-04	-6.95	cervix	COSMIC cancer mutations	cervix	11793	44	16828	49	CHST11,NAV3,GNAQ,APBB1IP,ADAM28,DISC1,SORL1,FCHSD2,ST6GALNAC3,ABCC4,PLXDC2,ANKRD44,PTPRJ,ATP8B4,DSCAM,ZFHX3,ARHGAP24,PICALM,ARHGAP22,SYNDIG1,MAP4K4,ST6GAL1,TCF12,MED13L,MAML2,MEF2C,DIP2B,MAML3,HDAC9,QKI,KCNQ3,DOCK8,SSH2,ZSWIM6,TBC1D22A,FRMD4A,ITPR2,ELMO1,MEF2A,SLC8A1,SFMBT2,DOCK4,SLC9A9,ZBTB20
9.648e-04	-6.94	ZNF365 (zinc finger protein 365)	protein interactions	22891	18	2	19454	50	DSCAM,DISC1
9.750e-04	-6.93	regulation of cell adhesion	biological process	GO:0030155	807	8	18204	47	DOCK8,ST6GAL1,PTPRJ,DISC1,MAP4K4,ZFHX3,DSCAM,APBB1IP
9.903e-04	-6.92	skin-leg-malignant_melanoma	COSMIC cancer mutations	skin-leg-malignant_melanoma	549	7	16828	49	ZBTB20,SORL1,APBB1IP,SFMBT2,GNAQ,PTPRJ,PLXDC2
9.936e-04	-6.91	regulation of axon extension	biological process	GO:0030516	76	3	18204	47	DISC1,DIP2B,DSCAM
1.030e-03	-6.88	FLOT1 (flotillin 1)	protein interactions	10211	453	6	19454	50	DISC1,MAP4K4,PICALM,DIP2B,EPB41L2,SLC9A9
1.032e-03	-6.88	clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	clear_cell_renal_cell_carcinoma	13924	48	16828	49	APBB1IP,ADAM28,NAV3,SYNDIG1,PICALM,ST6GALNAC3,ZFHX3,MAML3,DIP2B,DOCK8,MAML2,MEF2C,SLC9A9,TBC1D22A,FRMD4A,ITPR2,GNAQ,FCHSD2,UBE2E2,SORL1,DISC1,CHST11,MAP4K4,ST6GAL1,ARHGAP24,ARHGAP22,PLXDC2,PTPRJ,ANKRD44,ABCC4,ATP8B4,DSCAM,HDAC9,QKI,KCNQ3,MED13L,TCF12,EPB41L2,DOCK4,SLC8A1,SFMBT2,ZFAND3,ZBTB20,ZSWIM6,SSH2,ARHGAP26,ELMO1,MEF2A
1.032e-03	-6.88	kidney-carcinoma-clear_cell_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-clear_cell_renal_cell_carcinoma	13924	48	16828	49	ABCC4,PTPRJ,ANKRD44,PLXDC2,DSCAM,ATP8B4,ARHGAP22,ARHGAP24,ST6GAL1,MAP4K4,CHST11,GNAQ,DISC1,SORL1,UBE2E2,FCHSD2,SSH2,ZSWIM6,MEF2A,ELMO1,ARHGAP26,SFMBT2,SLC8A1,DOCK4,EPB41L2,ZBTB20,ZFAND3,TCF12,MED13L,HDAC9,KCNQ3,QKI,ST6GALNAC3,ZFHX3,PICALM,SYNDIG1,NAV3,ADAM28,APBB1IP,TBC1D22A,ITPR2,FRMD4A,SLC9A9,MAML2,MEF2C,DIP2B,MAML3,DOCK8
1.040e-03	-6.87	regulation of biological process	biological process	GO:0050789	12079	41	18204	47	DISC1,LDLRAD4,ZBTB20,SORL1,APBB1IP,ABCC4,UBE2E2,TBC1D22A,SSH2,MEF2A,PTPRJ,FCHSD2,SFMBT2,DSCAM,DOCK4,DOCK8,KCNQ3,ST6GAL1,QKI,ARHGAP24,EPB41L2,MAML3,MAML2,TCF12,SLC8A1,ARHGAP22,PICALM,NAV3,FRMD4A,DIP2B,ARHGAP26,SYNDIG1,HDAC9,MAP4K4,ZFHX3,ITPR2,MED13L,MEF2C,GNAQ,ELMO1,CHST11
1.050e-03	-6.86	Rho GTPase activation protein	gene3d domains	1.10.555.10	66	3	14470	44	ARHGAP24,ARHGAP26,ARHGAP22
1.075e-03	-6.84	regulation of nervous system development	biological process	GO:0051960	456	6	18204	47	QKI,SYNDIG1,DIP2B,DSCAM,SORL1,DISC1
1.113e-03	-6.80	skin-arm-malignant_melanoma	COSMIC cancer mutations	skin-arm-malignant_melanoma	1308	11	16828	49	PTPRJ,MED13L,PLXDC2,ZFHX3,ATP8B4,GNAQ,SLC8A1,ADAM28,SORL1,ZBTB20,DOCK8
1.165e-03	-6.76	lung-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	lung-carcinoma-squamous_cell_carcinoma	14664	49	16828	49	TCF12,MED13L,HDAC9,KCNQ3,QKI,SSH2,ZSWIM6,MEF2A,ELMO1,ARHGAP26,SFMBT2,SLC8A1,DOCK4,EPB41L2,ZBTB20,ZFAND3,CHST11,GNAQ,SORL1,DISC1,UBE2E2,FCHSD2,ABCC4,ANKRD44,PTPRJ,PLXDC2,DSCAM,ATP8B4,ARHGAP22,ARHGAP24,ST6GAL1,MAP4K4,MAML2,MEF2C,DIP2B,MAML3,DOCK8,TBC1D22A,ITPR2,FRMD4A,SLC9A9,HS3ST4,NAV3,ADAM28,APBB1IP,ST6GALNAC3,ZFHX3,PICALM,SYNDIG1
1.194e-03	-6.73	MYF6 (myogenic factor 6)	protein interactions	4618	20	2	19454	50	TCF12,DISC1
1.194e-03	-6.73	HAND1 (heart and neural crest derivatives expressed 1)	protein interactions	9421	20	2	19454	50	MEF2A,TCF12
1.196e-03	-6.73	positive regulation of biological process	biological process	GO:0048518	6326	27	18204	47	TCF12,MAML2,MAML3,EPB41L2,PICALM,SLC8A1,NAV3,FRMD4A,HDAC9,DIP2B,SYNDIG1,MAP4K4,ZFHX3,MEF2C,SORL1,ZBTB20,DISC1,UBE2E2,APBB1IP,MEF2A,PTPRJ,FCHSD2,DSCAM,DOCK4,DOCK8,ST6GAL1,QKI
1.233e-03	-6.70	intracellular signaling cassette	biological process	GO:0141124	837	8	18204	47	DOCK8,MAP4K4,MEF2C,DOCK4,ITPR2,ELMO1,MEF2A,SLC8A1
1.264e-03	-6.67	signaling	biological process	GO:0023052	4968	23	18204	47	KCNQ3,CHST11,ELMO1,ARHGAP24,MEF2C,GNAQ,DOCK8,ITPR2,DOCK4,DSCAM,MAP4K4,FCHSD2,ARHGAP26,PTPRJ,MEF2A,SLC8A1,ABCC4,APBB1IP,ARHGAP22,MAML3,MAML2,DISC1,SORL1
1.271e-03	-6.67	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	oesophagus-middle_third-carcinoma-squamous_cell_carcinoma	3531	20	16828	49	DOCK8,SORL1,DIP2B,NAV3,MEF2C,MAML2,SLC9A9,ZBTB20,MAP4K4,EPB41L2,SYNDIG1,SFMBT2,SLC8A1,PICALM,MEF2A,ZFHX3,DSCAM,FRMD4A,ATP8B4,PTPRJ
1.281e-03	-6.66	middle_third	COSMIC cancer mutations	middle_third	3533	20	16828	49	SLC9A9,ZBTB20,SYNDIG1,MAP4K4,EPB41L2,SLC8A1,PICALM,SFMBT2,MEF2A,FRMD4A,ATP8B4,ZFHX3,DSCAM,PTPRJ,DOCK8,SORL1,DIP2B,NAV3,MEF2C,MAML2
1.284e-03	-6.66	arm	COSMIC cancer mutations	arm	1331	11	16828	49	GNAQ,DOCK8,ADAM28,SORL1,MED13L,SLC8A1,ZBTB20,PTPRJ,PLXDC2,ZFHX3,ATP8B4
1.306e-03	-6.64	SMAD binding	molecular function	GO:0046332	78	3	18094	50	LDLRAD4,MEF2A,TCF12
1.316e-03	-6.63	Glyco_trans_29	interpro domains	IPR001675	20	2	18521	50	ST6GAL1,ST6GALNAC3
1.328e-03	-6.62	negative regulation of cellular process	biological process	GO:0048523	5320	24	18204	47	NAV3,FRMD4A,SSH2,DIP2B,MEF2A,PTPRJ,HDAC9,LDLRAD4,SORL1,ZBTB20,SLC8A1,PICALM,MEF2C,DOCK8,GNAQ,CHST11,ST6GAL1,QKI,ARHGAP24,MAP4K4,ZFHX3,SFMBT2,ITPR2,DSCAM
1.331e-03	-6.62	early endosome membrane	cellular component	GO:0031901	195	4	19108	47	SORL1,SLC9A9,SYNDIG1,LDLRAD4
1.367e-03	-6.59	Glyco_transf_29	pfam domains	PF00777	20	2	17795	49	ST6GALNAC3,ST6GAL1
1.374e-03	-6.59	regulation of cell migration	biological process	GO:0030334	1061	9	18204	47	PTPRJ,HDAC9,NAV3,MEF2C,DOCK8,DOCK4,MAP4K4,LDLRAD4,SORL1
1.430e-03	-6.55	cell communication	biological process	GO:0007154	5010	23	18204	47	ITPR2,MAP4K4,CHST11,ELMO1,MEF2C,GNAQ,SLC8A1,ARHGAP22,MAML3,MAML2,ARHGAP26,DSCAM,DOCK4,FCHSD2,KCNQ3,ARHGAP24,DOCK8,ABCC4,APBB1IP,DISC1,SORL1,PTPRJ,MEF2A
1.452e-03	-6.54	GT29-like_sf	interpro domains	IPR038578	21	2	18521	50	ST6GAL1,ST6GALNAC3
1.490e-03	-6.51	positive regulation of cell adhesion	biological process	GO:0045785	486	6	18204	47	APBB1IP,ZFHX3,MAP4K4,DISC1,PTPRJ,DOCK8
1.506e-03	-6.50	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	9	16828	49	SLC8A1,SFMBT2,GNAQ,ANKRD44,ATP8B4,ITPR2,ZFHX3,DSCAM,ELMO1
1.506e-03	-6.50	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	COSMIC cancer mutations	mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	951	9	16828	49	ANKRD44,ELMO1,ATP8B4,ITPR2,DSCAM,ZFHX3,SLC8A1,SFMBT2,GNAQ
1.517e-03	-6.49	skin-face-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-face-carcinoma-squamous_cell_carcinoma	2036	14	16828	49	ITPR2,ZFHX3,DSCAM,ABCC4,PTPRJ,SFMBT2,SLC8A1,PICALM,ARHGAP24,NAV3,MED13L,ADAM28,SORL1,KCNQ3
1.520e-03	-6.49	sialyltransferase activity	molecular function	GO:0008373	21	2	18094	50	ST6GALNAC3,ST6GAL1
1.553e-03	-6.47	SLC25A41 (solute carrier family 25 member 41)	protein interactions	284427	89	3	19454	50	MAP4K4,PICALM,GNAQ
1.558e-03	-6.46	positive regulation of cellular process	biological process	GO:0048522	5719	25	18204	47	ZFHX3,MAP4K4,MEF2C,PICALM,TCF12,EPB41L2,MAML3,MAML2,HDAC9,SYNDIG1,FRMD4A,NAV3,DOCK4,DSCAM,FCHSD2,QKI,ST6GAL1,DOCK8,UBE2E2,APBB1IP,SORL1,ZBTB20,DISC1,PTPRJ,MEF2A
1.565e-03	-6.46	neuron differentiation	biological process	GO:0030182	1081	9	18204	47	MEF2C,HDAC9,KCNQ3,MEF2A,ZSWIM6,DISC1,MAP4K4,DSCAM,PICALM
1.568e-03	-6.46	regulation of leukocyte apoptotic process	biological process	GO:2000106	89	3	18204	47	MEF2C,DOCK8,ST6GAL1
1.572e-03	-6.46	Myh9 (myosin, heavy polypeptide 9, non-muscle)	protein interactions	17886	195	4	19454	50	EPB41L2,SSH2,PICALM,ZBTB20
1.606e-03	-6.43	Signaling by NOTCH1	REACTOME pathways	R-HSA-1980143	73	3	10285	33	MAML2,HDAC9,MAML3
1.626e-03	-6.42	FERM_1	prosite domains	PS00660	21	2	12186	35	EPB41L2,FRMD4A
1.637e-03	-6.42	negative regulation of biological process	biological process	GO:0048519	5737	25	18204	47	DOCK4,DSCAM,ITPR2,SFMBT2,ZFHX3,MAP4K4,ARHGAP24,QKI,ST6GAL1,CHST11,DOCK8,GNAQ,MEF2C,PICALM,SLC8A1,SORL1,ZBTB20,LDLRAD4,HDAC9,PTPRJ,DIP2B,MEF2A,SSH2,FRMD4A,NAV3
1.666e-03	-6.40	RhoGAP	smart domains	SM00324	64	3	9717	36	ARHGAP24,ARHGAP22,ARHGAP26
1.671e-03	-6.39	regulation of smooth muscle cell migration	biological process	GO:0014910	91	3	18204	47	MEF2C,SORL1,DOCK4
1.714e-03	-6.37	leg	COSMIC cancer mutations	leg	969	9	16828	49	PTPRJ,PLXDC2,SLC9A9,ZBTB20,SORL1,APBB1IP,SFMBT2,GNAQ,SLC8A1
1.716e-03	-6.37	NOTCH1 (notch receptor 1)	protein interactions	4851	338	5	19454	50	MAML2,ANKRD44,TCF12,MEF2C,MAML3
1.723e-03	-6.36	VGLL4 (vestigial like family member 4)	protein interactions	9686	24	2	19454	50	MEF2C,MEF2A
1.730e-03	-6.36	PH	pfam domains	PF00169	187	4	17795	49	ARHGAP24,ARHGAP26,ARHGAP22,APBB1IP
1.737e-03	-6.36	sodium ion import across plasma membrane	biological process	GO:0098719	24	2	18204	47	SLC8A1,SLC9A9
1.761e-03	-6.34	mesothelioma	COSMIC cancer mutations	mesothelioma	4477	23	16828	49	ARHGAP26,FRMD4A,ITPR2,SLC9A9,MED13L,MAML2,TCF12,MEF2C,HDAC9,QKI,PTPRJ,ANKRD44,MAP4K4,ST6GAL1,PICALM,ARHGAP24,ARHGAP22,NAV3,GNAQ,FCHSD2,APBB1IP,UBE2E2,ADAM28
1.778e-03	-6.33	Golgi apparatus	cellular component	GO:0005794	1645	11	19108	47	LDLRAD4,GNAQ,ST6GAL1,ATP8B4,ABCC4,SORL1,DOCK4,CHST11,ST6GALNAC3,PICALM,HS3ST4
1.779e-03	-6.33	regulation of extent of cell growth	biological process	GO:0061387	93	3	18204	47	DIP2B,DSCAM,DISC1
1.786e-03	-6.33	FERM_2	prosite domains	PS00661	22	2	12186	35	EPB41L2,FRMD4A
1.786e-03	-6.33	import into cell	biological process	GO:0098657	687	7	18204	47	PICALM,ELMO1,SLC8A1,KCNQ3,SLC9A9,SORL1,FCHSD2
1.829e-03	-6.30	Glycosyl transferase family 29	gene3d domains	3.90.1480.20	21	2	14470	44	ST6GAL1,ST6GALNAC3
1.844e-03	-6.30	Rho_GTPase_activation_prot	interpro domains	IPR008936	90	3	18521	50	ARHGAP22,ARHGAP24,ARHGAP26
1.873e-03	-6.28	skin-foot-malignant_melanoma	COSMIC cancer mutations	skin-foot-malignant_melanoma	84	3	16828	49	ADAM28,GNAQ,PTPRJ
1.890e-03	-6.27	cardiac muscle cell differentiation	biological process	GO:0055007	95	3	18204	47	MEF2A,SLC8A1,MEF2C
1.898e-03	-6.27	FERM_CS	interpro domains	IPR019747	24	2	18521	50	FRMD4A,EPB41L2
1.913e-03	-6.26	human chr6q23.1-q23.2	chromosome location	human chr6q23.1-q23.2	1	1	26134	50	EPB41L2
1.913e-03	-6.26	human chr16q22.2-q22.3	chromosome location	human chr16q22.2-q22.3	1	1	26134	50	ZFHX3
1.913e-03	-6.26	human chr10q11.22-q11.23	chromosome location	human chr10q11.22-q11.23	1	1	26134	50	ARHGAP22
1.913e-03	-6.26	human chr7p14.2-p14.1	chromosome location	human chr7p14.2-p14.1	1	1	26134	50	ELMO1
1.913e-03	-6.26	human chr4q21.23-q21.3	chromosome location	human chr4q21.23-q21.3	1	1	26134	50	ARHGAP24
2.023e-03	-6.20	regulation of cell motility	biological process	GO:2000145	1122	9	18204	47	NAV3,MEF2C,DOCK8,PTPRJ,HDAC9,MAP4K4,LDLRAD4,SORL1,DOCK4
2.038e-03	-6.20	positive regulation of focal adhesion assembly	biological process	GO:0051894	26	2	18204	47	MAP4K4,PTPRJ
2.118e-03	-6.16	renal_cell_carcinoma	COSMIC cancer mutations	renal_cell_carcinoma	4535	23	16828	49	ANKRD44,PTPRJ,ARHGAP22,PICALM,ARHGAP24,MAP4K4,ST6GAL1,NAV3,GNAQ,ADAM28,APBB1IP,UBE2E2,FCHSD2,ITPR2,FRMD4A,ARHGAP26,SLC9A9,TCF12,MAML2,MED13L,MEF2C,HDAC9,QKI
2.118e-03	-6.16	kidney-carcinoma-renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-renal_cell_carcinoma	4535	23	16828	49	ARHGAP26,FRMD4A,ITPR2,SLC9A9,MED13L,MAML2,TCF12,MEF2C,HDAC9,QKI,ANKRD44,PTPRJ,MAP4K4,ST6GAL1,PICALM,ARHGAP24,ARHGAP22,NAV3,GNAQ,FCHSD2,APBB1IP,UBE2E2,ADAM28
2.118e-03	-6.16	muscle structure development	biological process	GO:0061061	521	6	18204	47	QKI,SLC8A1,MEF2A,TCF12,ZFHX3,MEF2C
2.127e-03	-6.15	activation of GTPase activity	biological process	GO:0090630	99	3	18204	47	TBC1D22A,ARHGAP22,ARHGAP24
2.146e-03	-6.14	Globo Sphingolipid Metabolism	WikiPathways	WP1424	22	2	5310	17	ST6GAL1,ST6GALNAC3
2.168e-03	-6.13	ANXA6 (annexin A6)	protein interactions	309	100	3	19454	50	ARHGAP24,DOCK8,CHST11
2.168e-03	-6.13	HRAS (HRas proto-oncogene, GTPase)	protein interactions	3265	712	7	19454	50	EPB41L2,FRMD4A,APBB1IP,GNAQ,PTPRJ,DOCK8,MAP4K4
2.215e-03	-6.11	ERK/MAPK targets	REACTOME pathways	R-HSA-198753	22	2	10285	33	MEF2C,MEF2A
2.220e-03	-6.11	autonomic_ganglia-neuroblastoma	COSMIC cancer mutations	autonomic_ganglia-neuroblastoma	3970	21	16828	49	ATP8B4,ZFHX3,ELMO1,ARHGAP26,ABCC4,TBC1D22A,PICALM,SLC8A1,DOCK4,EPB41L2,MEF2C,CHST11,NAV3,MAML2,ADAM28,KCNQ3,SORL1,DOCK8,FCHSD2,GNAQ,DIP2B
2.227e-03	-6.11	neuroblastoma	COSMIC cancer mutations	neuroblastoma	3971	21	16828	49	DIP2B,GNAQ,DOCK8,FCHSD2,KCNQ3,ADAM28,SORL1,MAML2,NAV3,MEF2C,CHST11,EPB41L2,DOCK4,PICALM,SLC8A1,TBC1D22A,ABCC4,ARHGAP26,ELMO1,ATP8B4,ZFHX3
2.261e-03	-6.09	skin-scalp-malignant_melanoma	COSMIC cancer mutations	skin-scalp-malignant_melanoma	634	7	16828	49	PTPRJ,MED13L,ARHGAP26,ARHGAP22,GNAQ,ADAM28,SORL1
2.345e-03	-6.06	regulation of cell junction assembly	biological process	GO:1901888	217	4	18204	47	PTPRJ,SYNDIG1,MEF2C,MAP4K4
2.362e-03	-6.05	skin-head_neck-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-head_neck-carcinoma-squamous_cell_carcinoma	14191	48	16828	49	MEF2C,MAML2,DOCK8,DIP2B,MAML3,FRMD4A,ITPR2,TBC1D22A,SLC9A9,NAV3,HS3ST4,APBB1IP,ADAM28,ZFHX3,ST6GALNAC3,PICALM,SYNDIG1,TCF12,MED13L,QKI,KCNQ3,HDAC9,ARHGAP26,ELMO1,MEF2A,SSH2,ZSWIM6,ZFAND3,ZBTB20,SLC8A1,SFMBT2,EPB41L2,DOCK4,CHST11,SORL1,DISC1,FCHSD2,GNAQ,ATP8B4,DSCAM,ABCC4,PLXDC2,PTPRJ,ANKRD44,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4
2.401e-03	-6.03	FERM_PH-like_C	interpro domains	IPR018980	27	2	18521	50	EPB41L2,FRMD4A
2.424e-03	-6.02	GRK2 (G protein-coupled receptor kinase 2)	protein interactions	156	104	3	19454	50	GNAQ,ARHGAP24,PTPRJ
2.441e-03	-6.02	regulation of hydrolase activity	biological process	GO:0051336	726	7	18204	47	ARHGAP24,TBC1D22A,DOCK8,GNAQ,MEF2C,ARHGAP22,MAP4K4
2.448e-03	-6.01	circulatory system development	biological process	GO:0072359	933	8	18204	47	PTPRJ,MEF2A,QKI,ARHGAP24,HDAC9,MEF2C,SLC8A1,ARHGAP22
2.455e-03	-6.01	SMAD2 (SMAD family member 2)	protein interactions	4087	367	5	19454	50	DOCK8,LDLRAD4,MEF2C,MEF2A,TCF12
2.490e-03	-6.00	autonomic_ganglia	COSMIC cancer mutations	autonomic_ganglia	4005	21	16828	49	DIP2B,GNAQ,DOCK8,FCHSD2,ADAM28,KCNQ3,SORL1,MAML2,NAV3,MEF2C,CHST11,DOCK4,EPB41L2,SLC8A1,PICALM,TBC1D22A,ABCC4,ELMO1,ARHGAP26,ATP8B4,ZFHX3
2.495e-03	-5.99	FERM_C	pfam domains	PF09380	27	2	17795	49	EPB41L2,FRMD4A
2.506e-03	-5.99	regulation of cell-substrate adhesion	biological process	GO:0010810	221	4	18204	47	PTPRJ,ST6GAL1,DISC1,MAP4K4
2.509e-03	-5.99	generation of neurons	biological process	GO:0048699	1158	9	18204	47	DSCAM,PICALM,MAP4K4,DISC1,ZSWIM6,KCNQ3,MEF2A,HDAC9,MEF2C
2.570e-03	-5.96	NTA1 (amidase)	protein interactions	853525	1	1	19454	50	DOCK8
2.570e-03	-5.96	ZNF781 (zinc finger protein 781)	protein interactions	163115	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	ZNF729 (zinc finger protein 729)	protein interactions	100287226	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	ZNF75D (zinc finger protein 75D)	protein interactions	7626	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	ZNF780B (zinc finger protein 780B)	protein interactions	163131	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	PLCB2 (phospholipase C beta 2)	protein interactions	664713	1	1	19454	50	GNAQ
2.570e-03	-5.96	ZNF880 (zinc finger protein 880)	protein interactions	400713	1	1	19454	50	ARHGAP24
2.570e-03	-5.96	EUC1 (Euc1p)	protein interactions	855138	1	1	19454	50	DOCK8
2.577e-03	-5.96	upper_back	COSMIC cancer mutations	upper_back	328	5	16828	49	ELMO1,ATP8B4,KCNQ3,PTPRJ,GNAQ
2.581e-03	-5.96	FERM_N	interpro domains	IPR018979	28	2	18521	50	EPB41L2,FRMD4A
2.582e-03	-5.96	memory T cell proliferation	biological process	GO:0061485	1	1	18204	47	DOCK8
2.582e-03	-5.96	positive regulation of early endosome to recycling endosome transport	biological process	GO:1902955	1	1	18204	47	SORL1
2.582e-03	-5.96	apoptosome assembly	biological process	GO:0097314	1	1	18204	47	KCNQ3
2.582e-03	-5.96	negative regulation of neurofibrillary tangle assembly	biological process	GO:1902997	1	1	18204	47	SORL1
2.582e-03	-5.96	membrane bending	biological process	GO:0097753	1	1	18204	47	PICALM
2.582e-03	-5.96	sinoatrial valve morphogenesis	biological process	GO:0003185	1	1	18204	47	MEF2C
2.638e-03	-5.94	cytoplasm	cellular component	GO:0005737	12081	39	19108	47	ST6GAL1,SSH2,ATP8B4,ZFHX3,DOCK8,TCF12,PTPRJ,MEF2A,EPB41L2,PICALM,HS3ST4,SLC9A9,CHST11,DISC1,SFMBT2,DOCK4,ZBTB20,APBB1IP,FCHSD2,QKI,ELMO1,FRMD4A,ADAM28,ITPR2,GNAQ,ARHGAP26,LDLRAD4,DIP2B,SLC8A1,MEF2C,SYNDIG1,ARHGAP22,HDAC9,ARHGAP24,KCNQ3,ST6GALNAC3,MAP4K4,SORL1,ABCC4
2.682e-03	-5.92	FERM_N	pfam domains	PF09379	28	2	17795	49	EPB41L2,FRMD4A
2.700e-03	-5.91	FCHSD2_SH3_2	interpro domains	IPR035556	1	1	18521	50	FCHSD2
2.700e-03	-5.91	DHR2_DOCK4	interpro domains	IPR037014	1	1	18521	50	DOCK4
2.700e-03	-5.91	GRAF_SH3	interpro domains	IPR035481	1	1	18521	50	ARHGAP26
2.700e-03	-5.91	MBT_SFMBT2_rpt1	interpro domains	IPR047353	1	1	18521	50	SFMBT2
2.700e-03	-5.91	DISC1	interpro domains	IPR026081	1	1	18521	50	DISC1
2.700e-03	-5.91	ABCC4_TMD1	interpro domains	IPR030240	1	1	18521	50	ABCC4
2.700e-03	-5.91	STAR_dimer	interpro domains	IPR032377	1	1	18521	50	QKI
2.700e-03	-5.91	K_chnl_volt-dep_KCNQ3	interpro domains	IPR003948	1	1	18521	50	KCNQ3
2.700e-03	-5.91	ABCC4_TMD2	interpro domains	IPR047083	1	1	18521	50	ABCC4
2.700e-03	-5.91	GRAF_BAR	interpro domains	IPR035483	1	1	18521	50	ARHGAP26
2.700e-03	-5.91	Quaking_NLS	interpro domains	IPR032367	1	1	18521	50	QKI
2.700e-03	-5.91	MBT_SFMBT2_rpt3	interpro domains	IPR047354	1	1	18521	50	SFMBT2
2.700e-03	-5.91	NaCa_exhngr1	interpro domains	IPR002987	1	1	18521	50	SLC8A1
2.700e-03	-5.91	DOCK4_SH3	interpro domains	IPR035769	1	1	18521	50	DOCK4
2.700e-03	-5.91	MAML2_TAD	interpro domains	IPR048452	1	1	18521	50	MAML2
2.700e-03	-5.91	Mediator_Med13_N	interpro domains	IPR021643	1	1	18521	50	MED13L
2.700e-03	-5.91	MBT_SFMBT2_rpt4	interpro domains	IPR047355	1	1	18521	50	SFMBT2
2.700e-03	-5.91	FCHSD2_F-BAR_dom	interpro domains	IPR034934	1	1	18521	50	FCHSD2
2.721e-03	-5.91	cytoplasmic vesicle membrane	cellular component	GO:0030659	1230	9	19108	47	SORL1,ARHGAP26,PTPRJ,ABCC4,LDLRAD4,ATP8B4,SLC9A9,ITPR2,SYNDIG1
2.754e-03	-5.89	MAML2_TAD	pfam domains	PF20804	1	1	17795	49	MAML2
2.754e-03	-5.89	STAR_dimer	pfam domains	PF16544	1	1	17795	49	QKI
2.754e-03	-5.89	Quaking_NLS	pfam domains	PF16551	1	1	17795	49	QKI
2.754e-03	-5.89	Med13_N	pfam domains	PF11597	1	1	17795	49	MED13L
2.763e-03	-5.89	internal N(7)-methylguanine-containing RNA reader activity	molecular function	GO:0160089	1	1	18094	50	QKI
2.786e-03	-5.88	regulation of neurogenesis	biological process	GO:0050767	377	5	18204	47	DSCAM,QKI,DIP2B,SORL1,DISC1
2.842e-03	-5.86	NOTCH3 (notch receptor 3)	protein interactions	4854	110	3	19454	50	MAML2,ANKRD44,MAML3
2.859e-03	-5.86	BAND41	prints domains	PR00935	25	2	5227	17	FRMD4A,EPB41L2
2.860e-03	-5.86	Nuclear Events (kinase and transcription factor activation)	REACTOME pathways	R-HSA-198725	25	2	10285	33	MEF2A,MEF2C
2.860e-03	-5.86	Termination of O-glycan biosynthesis	REACTOME pathways	R-HSA-977068	25	2	10285	33	ST6GAL1,ST6GALNAC3
2.869e-03	-5.85	positive regulation of cell junction assembly	biological process	GO:1901890	110	3	18204	47	PTPRJ,SYNDIG1,MAP4K4
2.892e-03	-5.85	positive regulation of cell-substrate junction organization	biological process	GO:0150117	31	2	18204	47	PTPRJ,MAP4K4
2.892e-03	-5.85	viral protein processing	biological process	GO:0019082	31	2	18204	47	ST6GALNAC3,ST6GAL1
2.922e-03	-5.84	cell differentiation	biological process	GO:0030154	3645	18	18204	47	DSCAM,MAP4K4,ARHGAP24,QKI,KCNQ3,CHST11,MEF2C,ARHGAP22,PICALM,SLC8A1,ZSWIM6,TCF12,DISC1,HDAC9,PTPRJ,MEF2A,SSH2,NAV3
2.928e-03	-5.83	multicellular organism development	biological process	GO:0007275	3957	19	18204	47	MAP4K4,DSCAM,MEF2C,QKI,ARHGAP24,CHST11,KCNQ3,TCF12,ZSWIM6,DISC1,PICALM,ARHGAP22,SLC8A1,NAV3,HDAC9,DIP2B,MEF2A,PTPRJ,ARHGAP26
2.948e-03	-5.83	skin-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-carcinoma-squamous_cell_carcinoma	493	6	16828	49	GNAQ,ABCC4,SLC8A1,MAML2,MAML3,ARHGAP26
2.950e-03	-5.83	cellular developmental process	biological process	GO:0048869	3648	18	18204	47	HDAC9,PTPRJ,MEF2A,SSH2,NAV3,PICALM,ARHGAP22,SLC8A1,ZSWIM6,TCF12,DISC1,QKI,ARHGAP24,CHST11,KCNQ3,MEF2C,DSCAM,MAP4K4
3.041e-03	-5.80	-	gene3d domains	1.20.5.4010	1	1	14470	44	QKI
3.050e-03	-5.79	vesicle membrane	cellular component	GO:0012506	1251	9	19108	47	ARHGAP26,SORL1,ABCC4,LDLRAD4,PTPRJ,ATP8B4,SLC9A9,SYNDIG1,ITPR2
3.057e-03	-5.79	KCNQ5 (potassium voltage-gated channel subfamily Q member 5)	protein interactions	56479	32	2	19454	50	DISC1,KCNQ3
3.057e-03	-5.79	KRT222 (keratin 222)	protein interactions	125113	32	2	19454	50	EPB41L2,DSCAM
3.080e-03	-5.78	regulation of myeloid cell apoptotic process	biological process	GO:0033032	32	2	18204	47	ST6GAL1,MEF2C
3.096e-03	-5.78	dendrite development	biological process	GO:0016358	113	3	18204	47	MEF2A,PICALM,DSCAM
3.210e-03	-5.74	oesophagus	COSMIC cancer mutations	oesophagus	14970	49	16828	49	APBB1IP,ADAM28,NAV3,HS3ST4,PICALM,SYNDIG1,ZFHX3,ST6GALNAC3,DOCK8,DIP2B,MAML3,MEF2C,MAML2,SLC9A9,FRMD4A,ITPR2,TBC1D22A,UBE2E2,DISC1,SORL1,FCHSD2,GNAQ,CHST11,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4,ATP8B4,DSCAM,ABCC4,PLXDC2,ANKRD44,PTPRJ,QKI,KCNQ3,HDAC9,TCF12,MED13L,ZFAND3,ZBTB20,SLC8A1,SFMBT2,EPB41L2,DOCK4,ARHGAP26,ELMO1,MEF2A,SSH2,ZSWIM6
3.222e-03	-5.74	ARF6 (ADP ribosylation factor 6)	protein interactions	382	568	6	19454	50	EPB41L2,ZFHX3,SLC9A9,GNAQ,PICALM,MAP4K4
3.231e-03	-5.74	Canonical and Non-canonical Notch signaling	WikiPathways	WP3845	27	2	5310	17	MAML2,MAML3
3.241e-03	-5.73	positive regulation of multicellular organismal process	biological process	GO:0051240	1691	11	18204	47	SLC8A1,DSCAM,DISC1,SORL1,ZBTB20,MEF2A,SYNDIG1,PTPRJ,QKI,MEF2C,DOCK8
3.249e-03	-5.73	ZNF74 (zinc finger protein 74)	protein interactions	7625	33	2	19454	50	SORL1,ARHGAP24
3.249e-03	-5.73	KATNAL1 (katanin catalytic subunit A1 like 1)	protein interactions	84056	33	2	19454	50	DISC1,ARHGAP24
3.249e-03	-5.73	ELMO3 (engulfment and cell motility 3)	protein interactions	79767	33	2	19454	50	ELMO1,DOCK4
3.252e-03	-5.73	NACAEXCHNGR1	prints domains	PR01260	1	1	5227	17	SLC8A1
3.252e-03	-5.73	KCNQ3CHANNEL	prints domains	PR01462	1	1	5227	17	KCNQ3
3.258e-03	-5.73	signal transduction	biological process	GO:0007165	4637	21	18204	47	DISC1,MAML2,MAML3,SORL1,APBB1IP,SLC8A1,ARHGAP22,MEF2A,PTPRJ,ARHGAP26,MAP4K4,ITPR2,DOCK4,DSCAM,MEF2C,GNAQ,DOCK8,ELMO1,CHST11,KCNQ3,ARHGAP24
3.274e-03	-5.72	clathrin-dependent endocytosis	biological process	GO:0072583	33	2	18204	47	PICALM,FCHSD2
3.289e-03	-5.72	breast-carcinoma-basal_(triple-negative)_carcinoma	COSMIC cancer mutations	breast-carcinoma-basal_(triple-negative)_carcinoma	2981	17	16828	49	MEF2C,TCF12,MAML2,SORL1,GNAQ,MAML3,ZFHX3,ARHGAP26,ELMO1,MEF2A,ST6GALNAC3,SSH2,ABCC4,PTPRJ,SLC9A9,PICALM,ARHGAP24
3.289e-03	-5.72	basal_(triple-negative)_carcinoma	COSMIC cancer mutations	basal_(triple-negative)_carcinoma	2981	17	16828	49	MAML2,TCF12,MEF2C,MAML3,GNAQ,SORL1,PTPRJ,ST6GALNAC3,SSH2,ABCC4,ARHGAP26,ELMO1,MEF2A,ZFHX3,PICALM,ARHGAP24,SLC9A9
3.332e-03	-5.70	ovary-other-neoplasm	COSMIC cancer mutations	ovary-other-neoplasm	12717	45	16828	49	APBB1IP,ADAM28,NAV3,HS3ST4,PICALM,SYNDIG1,ZFHX3,ST6GALNAC3,DOCK8,DIP2B,MAML3,MEF2C,MAML2,SLC9A9,FRMD4A,ITPR2,TBC1D22A,UBE2E2,SORL1,GNAQ,CHST11,ARHGAP22,MAP4K4,ST6GAL1,ATP8B4,DSCAM,ABCC4,PLXDC2,ANKRD44,PTPRJ,QKI,KCNQ3,TCF12,MED13L,ZFAND3,ZBTB20,SLC8A1,SFMBT2,EPB41L2,DOCK4,ELMO1,ARHGAP26,MEF2A,SSH2,ZSWIM6
3.359e-03	-5.70	Hemostasis	REACTOME pathways	R-HSA-109582	632	7	10285	33	DOCK8,ABCC4,SLC8A1,ITPR2,APBB1IP,GNAQ,DOCK4
3.384e-03	-5.69	nuclear speck	cellular component	GO:0016607	414	5	19108	47	MAML2,MAML3,TCF12,SFMBT2,MEF2C
3.446e-03	-5.67	KALRN (kalirin RhoGEF kinase)	protein interactions	8997	34	2	19454	50	DISC1,DSCAM
3.590e-03	-5.63	ITSN1 (intersectin 1)	protein interactions	6453	245	4	19454	50	DISC1,DOCK4,FCHSD2,PICALM
3.681e-03	-5.60	regulation of synapse organization	biological process	GO:0050807	246	4	18204	47	MEF2C,DISC1,SYNDIG1,ARHGAP22
3.803e-03	-5.57	CSNK1D (casein kinase 1 delta)	protein interactions	1453	249	4	19454	50	ARHGAP22,EPB41L2,ARHGAP26,LDLRAD4
3.805e-03	-5.57	MED31 (mediator complex subunit 31)	protein interactions	51003	122	3	19454	50	QKI,ELMO1,MED13L
3.857e-03	-5.56	MNS1 (meiosis specific nuclear structural 1)	protein interactions	55329	36	2	19454	50	FCHSD2,DISC1
3.905e-03	-5.55	LIMA1 (LIM domain and actin binding 1)	protein interactions	51474	409	5	19454	50	SSH2,PICALM,DISC1,ZBTB20,ARHGAP24
3.906e-03	-5.55	breast-carcinoma	COSMIC cancer mutations	breast-carcinoma	15030	49	16828	49	ZSWIM6,SSH2,ARHGAP26,ELMO1,MEF2A,EPB41L2,DOCK4,SLC8A1,SFMBT2,ZFAND3,ZBTB20,MED13L,TCF12,HDAC9,QKI,KCNQ3,PLXDC2,ANKRD44,PTPRJ,ABCC4,ATP8B4,DSCAM,MAP4K4,ST6GAL1,ARHGAP24,ARHGAP22,CHST11,GNAQ,FCHSD2,UBE2E2,SORL1,DISC1,TBC1D22A,FRMD4A,ITPR2,SLC9A9,MAML2,MEF2C,MAML3,DIP2B,DOCK8,ST6GALNAC3,ZFHX3,SYNDIG1,PICALM,HS3ST4,NAV3,APBB1IP,ADAM28
4.010e-03	-5.52	regulation of synapse structure or activity	biological process	GO:0050803	252	4	18204	47	ARHGAP22,SYNDIG1,MEF2C,DISC1
4.020e-03	-5.52	action potential	biological process	GO:0001508	124	3	18204	47	KCNQ3,SLC8A1,GNAQ
4.020e-03	-5.52	cardiocyte differentiation	biological process	GO:0035051	124	3	18204	47	SLC8A1,MEF2A,MEF2C
4.020e-03	-5.52	positive regulation of cell-substrate adhesion	biological process	GO:0010811	124	3	18204	47	PTPRJ,MAP4K4,DISC1
4.053e-03	-5.51	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-non_functioning	COSMIC cancer mutations	adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-non_functioning	224	4	16828	49	HDAC9,PTPRJ,ABCC4,ATP8B4
4.071e-03	-5.50	TRNAU1AP (tRNA selenocysteine 1 associated protein 1)	protein interactions	54952	37	2	19454	50	QKI,ZBTB20
4.102e-03	-5.50	positive regulation of axon extension	biological process	GO:0045773	37	2	18204	47	DSCAM,DISC1
4.102e-03	-5.50	smooth muscle cell differentiation	biological process	GO:0051145	37	2	18204	47	MEF2C,QKI
4.106e-03	-5.50	Pre-NOTCH Transcription and Translation	REACTOME pathways	R-HSA-1912408	30	2	10285	33	MAML2,MAML3
4.112e-03	-5.49	regulation of cell-matrix adhesion	biological process	GO:0001952	125	3	18204	47	MAP4K4,DISC1,PTPRJ
4.113e-03	-5.49	negative regulation of locomotion	biological process	GO:0040013	413	5	18204	47	MEF2C,NAV3,LDLRAD4,PTPRJ,ST6GAL1
4.165e-03	-5.48	GET3 (guided entry of tail-anchored proteins factor 3, ATPase)	protein interactions	439	126	3	19454	50	DISC1,LDLRAD4,ZFHX3
4.186e-03	-5.48	cell projection	cellular component	GO:0042995	2398	13	19108	47	APBB1IP,FCHSD2,PTPRJ,DSCAM,DIP2B,GNAQ,DOCK8,SYNDIG1,ARHGAP24,KCNQ3,SLC8A1,DISC1,DOCK4
4.217e-03	-5.47	early endosome	cellular component	GO:0005769	436	5	19108	47	PICALM,SORL1,SLC9A9,LDLRAD4,SYNDIG1
4.258e-03	-5.46	PAX9 (paired box 9)	protein interactions	5083	127	3	19454	50	ARHGAP24,QKI,ZFHX3
4.289e-03	-5.45	superficial_spreading	COSMIC cancer mutations	superficial_spreading	1110	9	16828	49	KCNQ3,APBB1IP,SLC9A9,GNAQ,DIP2B,SLC8A1,ABCC4,TCF12,PLXDC2
4.290e-03	-5.45	PIMREG (PICALM interacting mitotic regulator)	protein interactions	54478	38	2	19454	50	PICALM,DOCK8
4.335e-03	-5.44	kidney-other-neoplasm	COSMIC cancer mutations	kidney-other-neoplasm	10653	40	16828	49	ANKRD44,PTPRJ,PLXDC2,ST6GALNAC3,ZFHX3,DSCAM,ATP8B4,MAP4K4,ST6GAL1,SYNDIG1,ARHGAP22,PICALM,ARHGAP24,NAV3,CHST11,GNAQ,SORL1,ADAM28,APBB1IP,UBE2E2,TBC1D22A,ZSWIM6,SSH2,ELMO1,ARHGAP26,ITPR2,FRMD4A,EPB41L2,SFMBT2,SLC8A1,ZBTB20,SLC9A9,ZFAND3,MAML2,MED13L,TCF12,DIP2B,DOCK8,KCNQ3,QKI
4.361e-03	-5.43	secretory vesicle	cellular component	GO:0099503	1076	8	19108	47	ABCC4,PTPRJ,DISC1,SYNDIG1,ITPR2,PICALM,SSH2,ATP8B4
4.380e-03	-5.43	MAPK targets/ Nuclear events mediated by MAP kinases	REACTOME pathways	R-HSA-450282	31	2	10285	33	MEF2A,MEF2C
4.380e-03	-5.43	Platelet calcium homeostasis	REACTOME pathways	R-HSA-418360	31	2	10285	33	ITPR2,SLC8A1
4.391e-03	-5.43	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_I	34	2	16828	49	QKI,GNAQ
4.419e-03	-5.42	FERM_C	smart domains	SM01196	27	2	9717	36	FRMD4A,EPB41L2
4.545e-03	-5.39	KIF3A (kinesin family member 3A)	protein interactions	11127	130	3	19454	50	DSCAM,DISC1,SSH2
4.601e-03	-5.38	SH3 Domains	gene3d domains	2.30.30.40	223	4	14470	44	FCHSD2,ELMO1,DOCK4,ARHGAP26
4.603e-03	-5.38	neuron projection	cellular component	GO:0043005	1331	9	19108	47	SLC8A1,FCHSD2,SYNDIG1,KCNQ3,DISC1,GNAQ,DOCK4,DSCAM,DIP2B
4.619e-03	-5.38	Cholinergic synapse	KEGG pathways	hsa04725	112	3	7161	22	GNAQ,KCNQ3,ITPR2
4.646e-03	-5.37	nuclear body	cellular component	GO:0016604	856	7	19108	47	MAML3,TCF12,SFMBT2,ZBTB20,MAML2,MEF2C,ZFHX3
4.654e-03	-5.37	SH3 domain binding	molecular function	GO:0017124	122	3	18094	50	ELMO1,QKI,DOCK4
4.687e-03	-5.36	response to calcium ion	biological process	GO:0051592	131	3	18204	47	MEF2A,KCNQ3,MEF2C
4.744e-03	-5.35	ACO1 (aconitase 1)	protein interactions	48	40	2	19454	50	DSCAM,ARHGAP24
4.781e-03	-5.34	forebrain neuron differentiation	biological process	GO:0021879	40	2	18204	47	DISC1,ZSWIM6
4.837e-03	-5.33	actin filament-based process	biological process	GO:0030029	616	6	18204	47	SSH2,QKI,MEF2A,ELMO1,ARHGAP26,EPB41L2
4.912e-03	-5.32	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-thalamus-glioma-astrocytoma_Grade_I	36	2	16828	49	QKI,GNAQ
4.913e-03	-5.32	stereocilium shaft	cellular component	GO:0120043	2	1	19108	47	FCHSD2
4.913e-03	-5.32	endosome to plasma membrane transport vesicle	cellular component	GO:0070381	2	1	19108	47	PICALM
4.954e-03	-5.31	Signaling by NOTCH2	REACTOME pathways	R-HSA-1980145	33	2	10285	33	MAML3,MAML2
4.954e-03	-5.31	Sialic acid metabolism	REACTOME pathways	R-HSA-4085001	33	2	10285	33	ST6GAL1,ST6GALNAC3
4.966e-03	-5.31	LDLR_class-A_CS	interpro domains	IPR023415	39	2	18521	50	LDLRAD4,SORL1
4.980e-03	-5.30	SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3)	protein interactions	9901	41	2	19454	50	ARHGAP24,DISC1
5.047e-03	-5.29	multicellular organismal process	biological process	GO:0032501	6177	25	18204	47	NAV3,HDAC9,ARHGAP26,DIP2B,TCF12,PICALM,ARHGAP22,SLC8A1,GNAQ,MEF2C,CHST11,MAP4K4,PTPRJ,MEF2A,SORL1,ZSWIM6,DISC1,ABCC4,APBB1IP,DOCK8,ARHGAP24,QKI,KCNQ3,DOCK4,DSCAM
5.049e-03	-5.29	Myo1c (myosin IC)	protein interactions	17913	135	3	19454	50	ITPR2,PICALM,SSH2
5.096e-03	-5.28	non_functioning	COSMIC cancer mutations	non_functioning	239	4	16828	49	ATP8B4,PTPRJ,HDAC9,ABCC4
5.134e-03	-5.27	ZNF736 (zinc finger protein 736)	protein interactions	728927	2	1	19454	50	EPB41L2
5.134e-03	-5.27	Ric8b (RIC8 guanine nucleotide exchange factor B)	protein interactions	237422	2	1	19454	50	GNAQ
5.134e-03	-5.27	ZNF680 (zinc finger protein 680)	protein interactions	340252	2	1	19454	50	ARHGAP24
5.134e-03	-5.27	Zfp521 (zinc finger protein 521)	protein interactions	225207	2	1	19454	50	HDAC9
5.134e-03	-5.27	Agtr1a (angiotensin II receptor, type 1a)	protein interactions	24180	2	1	19454	50	GNAQ
5.134e-03	-5.27	ZNF658B (zinc finger protein 658B (pseudogene))	protein interactions	401509	2	1	19454	50	ARHGAP24
5.157e-03	-5.27	negative regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905869	2	1	18204	47	QKI
5.157e-03	-5.27	NMDA selective glutamate receptor signaling pathway	biological process	GO:0098989	2	1	18204	47	MEF2C
5.157e-03	-5.27	regulation of action potential firing threshold	biological process	GO:0099611	2	1	18204	47	KCNQ3
5.157e-03	-5.27	myofibroblast contraction	biological process	GO:1990764	2	1	18204	47	QKI
5.157e-03	-5.27	nephron tubule epithelial cell differentiation	biological process	GO:0072160	2	1	18204	47	MEF2C
5.157e-03	-5.27	cAMP transport	biological process	GO:0070730	2	1	18204	47	ABCC4
5.157e-03	-5.27	polysaccharide localization	biological process	GO:0033037	2	1	18204	47	CHST11
5.157e-03	-5.27	regulation of alkaline phosphatase activity	biological process	GO:0010692	2	1	18204	47	MEF2C
5.157e-03	-5.27	muscle cell fate determination	biological process	GO:0007521	2	1	18204	47	MEF2C
5.157e-03	-5.27	AMPA selective glutamate receptor signaling pathway	biological process	GO:0098990	2	1	18204	47	MEF2C
5.157e-03	-5.27	sinoatrial valve development	biological process	GO:0003172	2	1	18204	47	MEF2C
5.157e-03	-5.27	regulation of neurofibrillary tangle assembly	biological process	GO:1902996	2	1	18204	47	SORL1
5.157e-03	-5.27	positive regulation of ARF protein signal transduction	biological process	GO:0032014	2	1	18204	47	MAP4K4
5.157e-03	-5.27	post-embryonic retina morphogenesis in camera-type eye	biological process	GO:0060060	2	1	18204	47	DSCAM
5.157e-03	-5.27	ERK5 cascade	biological process	GO:0070375	2	1	18204	47	MEF2A
5.157e-03	-5.27	substantia propria of cornea development	biological process	GO:1903701	2	1	18204	47	KCNQ3
5.157e-03	-5.27	cellular response to trichostatin A	biological process	GO:0035984	2	1	18204	47	MEF2C
5.157e-03	-5.27	response to trichostatin A	biological process	GO:0035983	2	1	18204	47	MEF2C
5.157e-03	-5.27	positive regulation of glial cell-derived neurotrophic factor production	biological process	GO:1900168	2	1	18204	47	SORL1
5.157e-03	-5.27	regulation of glial cell-derived neurotrophic factor production	biological process	GO:1900166	2	1	18204	47	SORL1
5.157e-03	-5.27	positive regulation of alkaline phosphatase activity	biological process	GO:0010694	2	1	18204	47	MEF2C
5.184e-03	-5.26	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I	37	2	16828	49	QKI,GNAQ
5.184e-03	-5.26	fourth_ventricle	COSMIC cancer mutations	fourth_ventricle	37	2	16828	49	QKI,GNAQ
5.191e-03	-5.26	PH_DOMAIN	prosite domains	PS50003	246	4	12186	35	APBB1IP,ARHGAP26,ARHGAP22,ARHGAP24
5.220e-03	-5.26	GNPTAB (N-acetylglucosamine-1-phosphate transferase subunits alpha and beta)	protein interactions	79158	42	2	19454	50	DISC1,DSCAM
5.220e-03	-5.26	NSMAF (neutral sphingomyelinase activation associated factor)	protein interactions	8439	42	2	19454	50	EPB41L2,DOCK8
5.319e-03	-5.24	histone deacetylase binding	molecular function	GO:0042826	128	3	18094	50	MEF2A,HDAC9,MEF2C
5.320e-03	-5.24	vascular process in circulatory system	biological process	GO:0003018	273	4	18204	47	DOCK4,ABCC4,PTPRJ,SLC8A1
5.378e-03	-5.23	cytoskeletal protein binding	molecular function	GO:0008092	989	8	18094	50	DISC1,DIP2B,MAP4K4,EPB41L2,SLC8A1,PICALM,NAV3,SSH2
5.392e-03	-5.22	Ankyrin-G_BS	interpro domains	IPR020969	2	1	18521	50	KCNQ3
5.392e-03	-5.22	ANTH_dom_sf	interpro domains	IPR014712	2	1	18521	50	PICALM
5.392e-03	-5.22	Med13_C	interpro domains	IPR009401	2	1	18521	50	MED13L
5.392e-03	-5.22	AP180-like	interpro domains	IPR045192	2	1	18521	50	PICALM
5.392e-03	-5.22	PLXDC	interpro domains	IPR031152	2	1	18521	50	PLXDC2
5.392e-03	-5.22	PTPRJ_TM	interpro domains	IPR041201	2	1	18521	50	PTPRJ
5.392e-03	-5.22	FCHSD_SH3_1	interpro domains	IPR035460	2	1	18521	50	FCHSD2
5.392e-03	-5.22	TMEPAI/LRAD4	interpro domains	IPR043445	2	1	18521	50	LDLRAD4
5.392e-03	-5.22	FRMD4A/B_FERM_C	interpro domains	IPR041785	2	1	18521	50	FRMD4A
5.392e-03	-5.22	MAML1_3_TAD1	interpro domains	IPR048456	2	1	18521	50	MAML3
5.392e-03	-5.22	Scm-like-4MBT1/2_SAM	interpro domains	IPR037604	2	1	18521	50	SFMBT2
5.392e-03	-5.22	MAML1_3_TAD2	interpro domains	IPR048455	2	1	18521	50	MAML3
5.392e-03	-5.22	MID_MedPIWI	interpro domains	IPR041285	2	1	18521	50	MED13L
5.392e-03	-5.22	C2_Dock-B	interpro domains	IPR037811	2	1	18521	50	DOCK4
5.392e-03	-5.22	FRMD4A/B	interpro domains	IPR047176	2	1	18521	50	FRMD4A
5.408e-03	-5.22	Signaling by NOTCH	REACTOME pathways	R-HSA-157118	112	3	10285	33	MAML3,MAML2,HDAC9
5.416e-03	-5.22	regulation of cell development	biological process	GO:0060284	839	7	18204	47	DIP2B,HDAC9,QKI,MEF2C,DSCAM,DISC1,SORL1
5.418e-03	-5.22	regulation of axonogenesis	biological process	GO:0050770	138	3	18204	47	DIP2B,DSCAM,DISC1
5.461e-03	-5.21	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-brainstem-glioma-astrocytoma_Grade_I	38	2	16828	49	QKI,GNAQ
5.500e-03	-5.20	MID_MedPIWI	pfam domains	PF18296	2	1	17795	49	MED13L
5.500e-03	-5.20	KCNQC3-Ank-G_bd	pfam domains	PF11956	2	1	17795	49	KCNQ3
5.500e-03	-5.20	PTP_tm	pfam domains	PF18861	2	1	17795	49	PTPRJ
5.500e-03	-5.20	MAML1_3_TAD2	pfam domains	PF20801	2	1	17795	49	MAML3
5.500e-03	-5.20	Med13_C	pfam domains	PF06333	2	1	17795	49	MED13L
5.500e-03	-5.20	MAML1_3_TAD1	pfam domains	PF20802	2	1	17795	49	MAML3
5.514e-03	-5.20	positive regulation of locomotion	biological process	GO:0040017	633	6	18204	47	DSCAM,DOCK4,MAP4K4,PTPRJ,HDAC9,DOCK8
5.519e-03	-5.20	beta-galactoside alpha-2,6-sialyltransferase activity	molecular function	GO:0003835	2	1	18094	50	ST6GAL1
5.519e-03	-5.20	netrin receptor binding	molecular function	GO:1990890	2	1	18094	50	DSCAM
5.519e-03	-5.20	histone H3K14 deacetylase activity	molecular function	GO:0031078	2	1	18094	50	HDAC9
5.519e-03	-5.20	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	molecular function	GO:0016404	2	1	18094	50	ABCC4
5.519e-03	-5.20	alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	molecular function	GO:0047290	2	1	18094	50	ST6GALNAC3
5.519e-03	-5.20	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	molecular function	GO:0050659	2	1	18094	50	CHST11
5.702e-03	-5.17	miRs in Muscle Cell Differentiation	WikiPathways	WP2012	36	2	5310	17	MEF2A,MEF2C
5.747e-03	-5.16	knee	COSMIC cancer mutations	knee	125	3	16828	49	GNAQ,PTPRJ,ADAM28
5.760e-03	-5.16	synaptic vesicle localization	biological process	GO:0097479	44	2	18204	47	PICALM,SYNDIG1
5.760e-03	-5.16	positive regulation of bone mineralization	biological process	GO:0030501	44	2	18204	47	SLC8A1,MEF2C
5.775e-03	-5.15	hand	COSMIC cancer mutations	hand	566	6	16828	49	ADAM28,SFMBT2,GNAQ,DIP2B,ATP8B4,DSCAM
5.808e-03	-5.15	STRN3 (striatin 3)	protein interactions	29966	142	3	19454	50	ARHGAP24,MAP4K4,TCF12
5.814e-03	-5.15	glycoprotein biosynthetic process	biological process	GO:0009101	280	4	18204	47	ST6GAL1,ST6GALNAC3,CHST11,HS3ST4
5.922e-03	-5.13	enzyme activator activity	molecular function	GO:0008047	599	6	18094	50	ARHGAP22,ARHGAP26,ARHGAP24,GNAQ,DOCK4,TBC1D22A
5.962e-03	-5.12	Ldl_recept_a	pfam domains	PF00057	42	2	17795	49	SORL1,LDLRAD4
5.998e-03	-5.12	Diseases of signal transduction	REACTOME pathways	R-HSA-5663202	369	5	10285	33	MAML3,QKI,MAML2,APBB1IP,HDAC9
6.000e-03	-5.12	Platelet activation	KEGG pathways	hsa04611	123	3	7161	22	ITPR2,APBB1IP,GNAQ
6.005e-03	-5.12	metal cation:monoatomic cation antiporter activity	molecular function	GO:0140828	42	2	18094	50	SLC9A9,SLC8A1
6.018e-03	-5.11	glutamate receptor signaling pathway	biological process	GO:0007215	45	2	18204	47	GNAQ,MEF2C
6.037e-03	-5.11	Calml3 (calmodulin-like 3)	protein interactions	70405	144	3	19454	50	ZBTB20,SSH2,PICALM
6.073e-03	-5.10	ANTH domain	gene3d domains	1.20.58.150	2	1	14470	44	PICALM
6.083e-03	-5.10	endomembrane system	cellular component	GO:0012505	4764	20	19108	47	ATP8B4,FCHSD2,ST6GAL1,SSH2,ITPR2,ARHGAP26,GNAQ,LDLRAD4,PTPRJ,HS3ST4,PICALM,SLC9A9,SYNDIG1,DOCK4,SORL1,DISC1,ST6GALNAC3,CHST11,NAV3,ABCC4
6.147e-03	-5.09	neuron development	biological process	GO:0048666	859	7	18204	47	KCNQ3,MEF2A,DSCAM,PICALM,MEF2C,MAP4K4,DISC1
6.224e-03	-5.08	fn3	pfam domains	PF00041	136	3	17795	49	PTPRJ,SORL1,DSCAM
6.233e-03	-5.08	skin-abdomen-malignant_melanoma	COSMIC cancer mutations	skin-abdomen-malignant_melanoma	404	5	16828	49	ABCC4,GNAQ,PTPRJ,ZFHX3,NAV3
6.234e-03	-5.08	PACS1 (phosphofurin acidic cluster sorting protein 1)	protein interactions	55690	46	2	19454	50	SORL1,ARHGAP24
6.295e-03	-5.07	Golgi membrane	cellular component	GO:0000139	683	6	19108	47	HS3ST4,SORL1,CHST11,ST6GALNAC3,ST6GAL1,LDLRAD4
6.338e-03	-5.06	Cell Differentiation - Index	WikiPathways	WP2029	38	2	5310	17	MEF2C,MEF2A
6.398e-03	-5.05	pleura	COSMIC cancer mutations	pleura	4914	23	16828	49	SLC9A9,FRMD4A,ITPR2,ARHGAP26,HDAC9,QKI,TCF12,MED13L,MAML2,MEF2C,PICALM,ARHGAP24,ARHGAP22,MAP4K4,ST6GAL1,ANKRD44,PTPRJ,GNAQ,APBB1IP,UBE2E2,ADAM28,FCHSD2,NAV3
6.402e-03	-5.05	skin-extremity-malignant_melanoma	COSMIC cancer mutations	skin-extremity-malignant_melanoma	1875	12	16828	49	SSH2,ATP8B4,DOCK4,MAP4K4,EPB41L2,SYNDIG1,MED13L,NAV3,HDAC9,FCHSD2,SORL1,APBB1IP
6.421e-03	-5.05	LDLRA_1	prosite domains	PS01209	42	2	12186	35	SORL1,LDLRAD4
6.426e-03	-5.05	cytoplasmic vesicle	cellular component	GO:0031410	2521	13	19108	47	ARHGAP26,LDLRAD4,PTPRJ,FCHSD2,ATP8B4,SSH2,ITPR2,SORL1,DISC1,ABCC4,PICALM,SLC9A9,SYNDIG1
6.429e-03	-5.05	extremity	COSMIC cancer mutations	extremity	1876	12	16828	49	SYNDIG1,DOCK4,EPB41L2,MAP4K4,ATP8B4,SSH2,FCHSD2,APBB1IP,SORL1,HDAC9,NAV3,MED13L
6.492e-03	-5.04	muscle cell differentiation	biological process	GO:0042692	289	4	18204	47	MEF2C,QKI,MEF2A,SLC8A1
6.499e-03	-5.04	positive regulation of catalytic activity	biological process	GO:0043085	868	7	18204	47	MAP4K4,ARHGAP22,GNAQ,DOCK8,TBC1D22A,MEF2C,ARHGAP24
6.500e-03	-5.04	ZNRF2 (zinc and ring finger 2)	protein interactions	223082	47	2	19454	50	UBE2E2,ANKRD44
6.556e-03	-5.03	intracellular vesicle	cellular component	GO:0097708	2527	13	19108	47	SLC9A9,SYNDIG1,PICALM,ABCC4,SORL1,DISC1,ITPR2,SSH2,ATP8B4,FCHSD2,LDLRAD4,PTPRJ,ARHGAP26
6.624e-03	-5.02	MCAM (melanoma cell adhesion molecule)	protein interactions	4162	464	5	19454	50	MAP4K4,DIP2B,PICALM,PTPRJ,EPB41L2
6.646e-03	-5.01	skin-trunk-malignant_melanoma	COSMIC cancer mutations	skin-trunk-malignant_melanoma	2647	15	16828	49	MAML2,TCF12,FCHSD2,APBB1IP,SORL1,ADAM28,DIP2B,ATP8B4,DSCAM,PTPRJ,ANKRD44,SSH2,ABCC4,SYNDIG1,SFMBT2
6.722e-03	-5.00	LDLRA_2	prosite domains	PS50068	43	2	12186	35	LDLRAD4,SORL1
6.806e-03	-4.99	MYH9 (myosin heavy chain 9)	protein interactions	4627	663	6	19454	50	ITPR2,SSH2,PICALM,ZBTB20,ARHGAP24,EPB41L2
6.812e-03	-4.99	neuronal cell body	cellular component	GO:0043025	489	5	19108	47	DSCAM,DIP2B,SLC8A1,PICALM,SORL1
6.824e-03	-4.99	regulation of amyloid-beta formation	biological process	GO:1902003	48	2	18204	47	SORL1,PICALM
6.836e-03	-4.99	cellular response to stimulus	biological process	GO:0051716	6307	25	18204	47	ARHGAP26,HDAC9,MAML2,MAML3,SLC8A1,ARHGAP22,MEF2C,GNAQ,CHST11,ELMO1,MAP4K4,ITPR2,PTPRJ,MEF2A,DISC1,ZBTB20,SORL1,ABCC4,APBB1IP,UBE2E2,DOCK8,KCNQ3,ARHGAP24,DOCK4,DSCAM
6.853e-03	-4.98	LDL_receptor-like_sf	interpro domains	IPR036055	46	2	18521	50	SORL1,LDLRAD4
6.853e-03	-4.98	LDrepeatLR_classA_rpt	interpro domains	IPR002172	46	2	18521	50	SORL1,LDLRAD4
6.939e-03	-4.97	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma	981	8	16828	49	DSCAM,ITPR2,PLXDC2,ST6GALNAC3,SLC9A9,UBE2E2,SLC8A1,GNAQ
7.049e-03	-4.95	CYTH1 (cytohesin 1)	protein interactions	9267	49	2	19454	50	FRMD4A,GNAQ
7.049e-03	-4.95	HBZ (hemoglobin subunit zeta)	protein interactions	3050	49	2	19454	50	DOCK8,ARHGAP24
7.055e-03	-4.95	positive regulation of nervous system development	biological process	GO:0051962	296	4	18204	47	SYNDIG1,QKI,DSCAM,DISC1
7.064e-03	-4.95	pelvis	COSMIC cancer mutations	pelvis	984	8	16828	49	NAV3,ZFHX3,SSH2,DOCK8,MAML3,SYNDIG1,MAP4K4,SLC8A1
7.099e-03	-4.95	response to stimulus	biological process	GO:0050896	7803	29	18204	47	DOCK8,KCNQ3,ARHGAP24,ST6GAL1,DSCAM,DOCK4,PTPRJ,MEF2A,DISC1,ZBTB20,SORL1,ABCC4,APBB1IP,UBE2E2,MEF2C,GNAQ,CHST11,ELMO1,ZFHX3,MAP4K4,ITPR2,SLC9A9,ARHGAP26,HDAC9,MAML3,MAML2,TCF12,SLC8A1,ARHGAP22
7.266e-03	-4.92	soft_tissue-striated_muscle-rhabdomyosarcoma	COSMIC cancer mutations	soft_tissue-striated_muscle-rhabdomyosarcoma	594	6	16828	49	ATP8B4,MEF2A,ARHGAP26,DIP2B,EPB41L2,DOCK4
7.330e-03	-4.92	MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3)	protein interactions	260425	50	2	19454	50	LDLRAD4,DSCAM
7.400e-03	-4.91	skin-face-malignant_melanoma	COSMIC cancer mutations	skin-face-malignant_melanoma	137	3	16828	49	ADAM28,PTPRJ,GNAQ
7.420e-03	-4.90	FERM_M	pfam domains	PF00373	47	2	17795	49	EPB41L2,FRMD4A
7.439e-03	-4.90	lymphocyte activation	biological process	GO:0046649	476	5	18204	47	MEF2C,DOCK8,APBB1IP,PTPRJ,HDAC9
7.443e-03	-4.90	FERM_domain	interpro domains	IPR000299	48	2	18521	50	FRMD4A,EPB41L2
7.462e-03	-4.90	regulation of cell differentiation	biological process	GO:0045595	1622	10	18204	47	MEF2C,QKI,HDAC9,DIP2B,SORL1,LDLRAD4,TCF12,ZFHX3,DISC1,DSCAM
7.568e-03	-4.88	secretory granule membrane	cellular component	GO:0030667	317	4	19108	47	ATP8B4,PTPRJ,ABCC4,ITPR2
7.592e-03	-4.88	third_ventricle	COSMIC cancer mutations	third_ventricle	45	2	16828	49	GNAQ,QKI
7.691e-03	-4.87	TULP1 (TUB like protein 1)	protein interactions	7287	3	1	19454	50	ARHGAP26
7.691e-03	-4.87	ZNF506 (zinc finger protein 506)	protein interactions	440515	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	ZNF682 (zinc finger protein 682)	protein interactions	91120	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	KLHL4 (kelch like family member 4)	protein interactions	56062	3	1	19454	50	DSCAM
7.691e-03	-4.87	ZNF257 (zinc finger protein 257)	protein interactions	113835	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	GALR2 (galanin receptor 2)	protein interactions	8811	3	1	19454	50	GNAQ
7.691e-03	-4.87	ADHFE1 (alcohol dehydrogenase iron containing 1)	protein interactions	137872	3	1	19454	50	GNAQ
7.691e-03	-4.87	ZNF549 (zinc finger protein 549)	protein interactions	256051	3	1	19454	50	SORL1
7.691e-03	-4.87	ZNF716 (zinc finger protein 716)	protein interactions	441234	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	Srr (serine racemase)	protein interactions	27364	3	1	19454	50	DISC1
7.691e-03	-4.87	ZNF540 (zinc finger protein 540)	protein interactions	163255	3	1	19454	50	ARHGAP24
7.691e-03	-4.87	HERC2P2 (HERC2 pseudogene 2)	protein interactions	400322	3	1	19454	50	DISC1
7.697e-03	-4.87	angioimmunoblastic_T_cell_lymphoma	COSMIC cancer mutations	angioimmunoblastic_T_cell_lymphoma	269	4	16828	49	GNAQ,ZFHX3,ITPR2,MEF2C
7.722e-03	-4.86	intracellular anatomical structure	cellular component	GO:0005622	15205	44	19108	47	EPB41L2,DOCK4,SFMBT2,DISC1,CHST11,ZBTB20,SSH2,TCF12,DOCK8,MED13L,PTPRJ,MEF2C,KCNQ3,HDAC9,SYNDIG1,MAML3,ABCC4,QKI,ITPR2,FRMD4A,ADAM28,ELMO1,GNAQ,LDLRAD4,HS3ST4,PICALM,SLC9A9,ATP8B4,ST6GAL1,ZFHX3,MEF2A,MAML2,SLC8A1,ARHGAP24,ARHGAP22,SORL1,MAP4K4,ST6GALNAC3,NAV3,FCHSD2,APBB1IP,ARHGAP26,DIP2B,UBE2E2
7.726e-03	-4.86	ventricular cardiac myofibril assembly	biological process	GO:0055005	3	1	18204	47	MEF2A
7.726e-03	-4.86	regulation of locomotor rhythm	biological process	GO:1904059	3	1	18204	47	ZFHX3
7.726e-03	-4.86	pyramidal neuron migration to cerebral cortex	biological process	GO:0021852	3	1	18204	47	DISC1
7.726e-03	-4.86	negative regulation of vascular associated smooth muscle contraction	biological process	GO:1904694	3	1	18204	47	DOCK4
7.726e-03	-4.86	action potential initiation	biological process	GO:0099610	3	1	18204	47	KCNQ3
7.726e-03	-4.86	regulation of synaptic activity	biological process	GO:0060025	3	1	18204	47	MEF2C
7.726e-03	-4.86	positive regulation of macrophage apoptotic process	biological process	GO:2000111	3	1	18204	47	MEF2C
7.726e-03	-4.86	primary heart field specification	biological process	GO:0003138	3	1	18204	47	MEF2C
7.726e-03	-4.86	inhibitory chemical synaptic transmission	biological process	GO:0098977	3	1	18204	47	KCNQ3
7.747e-03	-4.86	FERM_central	interpro domains	IPR019748	49	2	18521	50	FRMD4A,EPB41L2
7.800e-03	-4.85	abdomen	COSMIC cancer mutations	abdomen	603	6	16828	49	PTPRJ,ABCC4,GNAQ,NAV3,ZFHX3,ITPR2
7.876e-03	-4.84	plasma membrane bounded cell projection	cellular component	GO:0120025	2285	12	19108	47	SLC8A1,FCHSD2,APBB1IP,KCNQ3,SYNDIG1,DOCK4,GNAQ,DOCK8,DISC1,DIP2B,DSCAM,PTPRJ
7.886e-03	-4.84	intracellular organelle	cellular component	GO:0043229	13594	41	19108	47	TCF12,PTPRJ,MAML2,MEF2A,MED13L,ST6GAL1,SSH2,ATP8B4,ZFHX3,DISC1,CHST11,SFMBT2,DOCK4,ZBTB20,EPB41L2,PICALM,HS3ST4,SLC9A9,GNAQ,ARHGAP26,LDLRAD4,UBE2E2,DIP2B,APBB1IP,FCHSD2,QKI,FRMD4A,ADAM28,ITPR2,ST6GALNAC3,MAML3,SORL1,ABCC4,NAV3,SLC8A1,MEF2C,ARHGAP22,SYNDIG1,HDAC9,ARHGAP24,KCNQ3
7.909e-03	-4.84	SCMH1 (Scm polycomb group protein homolog 1)	protein interactions	22955	52	2	19454	50	MAML3,SFMBT2
7.969e-03	-4.83	forebrain generation of neurons	biological process	GO:0021872	52	2	18204	47	ZSWIM6,DISC1
7.969e-03	-4.83	regulation of vascular associated smooth muscle cell migration	biological process	GO:1904752	52	2	18204	47	MEF2C,DOCK4
8.056e-03	-4.82	FERM_2	interpro domains	IPR035963	50	2	18521	50	FRMD4A,EPB41L2
8.078e-03	-4.82	Dip2-like_dom	interpro domains	IPR037337	3	1	18521	50	DIP2B
8.078e-03	-4.82	Na_Ca_Ex_C-exten	interpro domains	IPR032452	3	1	18521	50	SLC8A1
8.078e-03	-4.82	SSH-N	interpro domains	IPR043588	3	1	18521	50	SSH2
8.078e-03	-4.82	NHE-6/7/9	interpro domains	IPR002090	3	1	18521	50	SLC9A9
8.078e-03	-4.82	ELMO_ARM	interpro domains	IPR024574	3	1	18521	50	ELMO1
8.078e-03	-4.82	Hist_deacetylase_Gln_rich_N	interpro domains	IPR024643	3	1	18521	50	HDAC9
8.078e-03	-4.82	Nav/unc-53	interpro domains	IPR039041	3	1	18521	50	NAV3
8.078e-03	-4.82	Phosphatase_SSH-like	interpro domains	IPR043587	3	1	18521	50	SSH2
8.078e-03	-4.82	Na_Ca_Ex	interpro domains	IPR004836	3	1	18521	50	SLC8A1
8.078e-03	-4.82	InsP3_rcpt	interpro domains	IPR000493	3	1	18521	50	ITPR2
8.078e-03	-4.82	C2_Dock-C	interpro domains	IPR037808	3	1	18521	50	DOCK8
8.190e-03	-4.80	C11orf52 (chromosome 11 open reading frame 52)	protein interactions	91894	310	4	19454	50	DIP2B,MAP4K4,PICALM,EPB41L2
8.206e-03	-4.80	ELMO2 (engulfment and cell motility 2)	protein interactions	63916	53	2	19454	50	DOCK4,ELMO1
8.234e-03	-4.80	Low-density Lipoprotein Receptor	gene3d domains	4.10.400.10	45	2	14470	44	LDLRAD4,SORL1
8.238e-03	-4.80	HDAC4_Gln	pfam domains	PF12203	3	1	17795	49	HDAC9
8.238e-03	-4.80	Na_Ca_ex_C	pfam domains	PF16494	3	1	17795	49	SLC8A1
8.238e-03	-4.80	ELMO_ARM	pfam domains	PF11841	3	1	17795	49	ELMO1
8.268e-03	-4.80	histone H4K16 deacetylase activity	molecular function	GO:0034739	3	1	18094	50	HDAC9
8.268e-03	-4.80	inositol 1,4,5-trisphosphate-gated calcium channel activity	molecular function	GO:0005220	3	1	18094	50	ITPR2
8.268e-03	-4.80	histone H4K deacetylase activity	molecular function	GO:0141051	3	1	18094	50	HDAC9
8.268e-03	-4.80	histone H3K9 deacetylase activity	molecular function	GO:0032129	3	1	18094	50	HDAC9
8.268e-03	-4.80	regulation of platelet activation	biological process	GO:0010543	53	2	18204	47	GNAQ,PTPRJ
8.321e-03	-4.79	FERM_3	prosite domains	PS50057	48	2	12186	35	FRMD4A,EPB41L2
8.343e-03	-4.79	TEAD1 (TEA domain transcription factor 1)	protein interactions	7003	162	3	19454	50	ZFHX3,MEF2C,MEF2A
8.370e-03	-4.78	Band_41_domain	interpro domains	IPR019749	51	2	18521	50	EPB41L2,FRMD4A
8.370e-03	-4.78	FERM/acyl-CoA-bd_prot_sf	interpro domains	IPR014352	51	2	18521	50	EPB41L2,FRMD4A
8.484e-03	-4.77	MORF4L2 (mortality factor 4 like 2)	protein interactions	9643	163	3	19454	50	DISC1,DSCAM,HDAC9
8.505e-03	-4.77	regulation of catalytic activity	biological process	GO:0050790	1395	9	18204	47	ARHGAP22,SLC8A1,MAP4K4,ARHGAP24,PTPRJ,TBC1D22A,DOCK8,GNAQ,MEF2C
8.507e-03	-4.77	TAFA4 (TAFA chemokine like family member 4)	protein interactions	151647	54	2	19454	50	SORL1,ITPR2
8.542e-03	-4.76	chemical homeostasis	biological process	GO:0048878	914	7	18204	47	PICALM,SLC8A1,ZBTB20,DISC1,HDAC9,PTPRJ,SLC9A9
8.565e-03	-4.76	receptor-mediated endocytosis	biological process	GO:0006898	163	3	18204	47	SORL1,FCHSD2,PICALM
8.572e-03	-4.76	viral gene expression	biological process	GO:0019080	54	2	18204	47	ST6GALNAC3,ST6GAL1
8.572e-03	-4.76	positive regulation of ossification	biological process	GO:0045778	54	2	18204	47	SLC8A1,MEF2C
8.572e-03	-4.76	positive regulation of biomineral tissue development	biological process	GO:0070169	54	2	18204	47	SLC8A1,MEF2C
8.649e-03	-4.75	regulation of developmental growth	biological process	GO:0048638	314	4	18204	47	DIP2B,DSCAM,MEF2C,DISC1
8.711e-03	-4.74	skin-hand-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-hand-benign_melanocytic_nevus-blue	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-leg-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-leg-benign_melanocytic_nevus-blue	3	1	16828	49	GNAQ
8.711e-03	-4.74	eye-uveal_tract-melanocytoma	COSMIC cancer mutations	eye-uveal_tract-melanocytoma	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-abdomen-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-abdomen-benign_melanocytic_nevus-blue	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-ankle-benign_melanocytic_nevus	COSMIC cancer mutations	skin-ankle-benign_melanocytic_nevus	3	1	16828	49	GNAQ
8.711e-03	-4.74	eye-conjunctiva-other-primary_acquired_melanosis	COSMIC cancer mutations	eye-conjunctiva-other-primary_acquired_melanosis	3	1	16828	49	GNAQ
8.711e-03	-4.74	central_nervous_system-posterior_fossa-other-gangliocytoma	COSMIC cancer mutations	central_nervous_system-posterior_fossa-other-gangliocytoma	3	1	16828	49	GNAQ
8.711e-03	-4.74	central_nervous_system-temporal_lobe-glioma-astroblastoma	COSMIC cancer mutations	central_nervous_system-temporal_lobe-glioma-astroblastoma	3	1	16828	49	GNAQ
8.711e-03	-4.74	primary_acquired_melanosis	COSMIC cancer mutations	primary_acquired_melanosis	3	1	16828	49	GNAQ
8.711e-03	-4.74	malignant_blue_nevus	COSMIC cancer mutations	malignant_blue_nevus	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-shoulder-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-shoulder-benign_melanocytic_nevus-blue	3	1	16828	49	GNAQ
8.711e-03	-4.74	eye-conjunctiva-benign_melanocytic_nevus	COSMIC cancer mutations	eye-conjunctiva-benign_melanocytic_nevus	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-back-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-back-benign_melanocytic_nevus-blue	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-groin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-groin-benign_melanocytic_nevus	3	1	16828	49	GNAQ
8.711e-03	-4.74	extraocular	COSMIC cancer mutations	extraocular	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-forearm-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-forearm-benign_melanocytic_nevus-blue	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-foot-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-foot-benign_melanocytic_nevus-blue	3	1	16828	49	GNAQ
8.711e-03	-4.74	skin-trunk-benign_melanocytic_nevus	COSMIC cancer mutations	skin-trunk-benign_melanocytic_nevus	3	1	16828	49	GNAQ
8.744e-03	-4.74	muscle organ development	biological process	GO:0007517	315	4	18204	47	TCF12,ZFHX3,MEF2C,MEF2A
8.745e-03	-4.74	enzyme regulator activity	molecular function	GO:0030234	1305	9	18094	50	ARHGAP22,ELMO1,SORL1,DOCK8,ARHGAP26,ARHGAP24,GNAQ,DOCK4,TBC1D22A
8.814e-03	-4.73	GJB7 (gap junction protein beta 7)	protein interactions	375519	55	2	19454	50	GNAQ,EPB41L2
8.881e-03	-4.72	regulation of amyloid precursor protein catabolic process	biological process	GO:1902991	55	2	18204	47	SORL1,PICALM
8.881e-03	-4.72	membrane depolarization	biological process	GO:0051899	55	2	18204	47	KCNQ3,SLC8A1
8.917e-03	-4.72	RBM11 (RNA binding motif protein 11)	protein interactions	54033	166	3	19454	50	ZFHX3,MED13L,QKI
8.959e-03	-4.72	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	ko04961	47	2	7161	22	GNAQ,SLC8A1
8.959e-03	-4.72	Endocrine and other factor-regulated calcium reabsorption	KEGG pathways	hsa04961	47	2	7161	22	GNAQ,SLC8A1
8.967e-03	-4.71	stereocilium	cellular component	GO:0032420	58	2	19108	47	FCHSD2,DOCK4
9.023e-03	-4.71	endocytosis	biological process	GO:0006897	499	5	18204	47	PICALM,ELMO1,KCNQ3,SORL1,FCHSD2
9.095e-03	-4.70	-	gene3d domains	6.10.250.1550	3	1	14470	44	HDAC9
9.095e-03	-4.70	-	gene3d domains	6.10.250.810	3	1	14470	44	ELMO1
9.139e-03	-4.70	foot	COSMIC cancer mutations	foot	148	3	16828	49	GNAQ,PTPRJ,ADAM28
9.195e-03	-4.69	negative regulation of leukocyte apoptotic process	biological process	GO:2000107	56	2	18204	47	DOCK8,ST6GAL1
9.299e-03	-4.68	positive regulation of developmental growth	biological process	GO:0048639	168	3	18204	47	MEF2C,DISC1,DSCAM
9.331e-03	-4.67	Notch signaling pathway	KEGG pathways	ko04330	48	2	7161	22	MAML2,MAML3
9.331e-03	-4.67	Notch signaling pathway	KEGG pathways	hsa04330	48	2	7161	22	MAML3,MAML2
9.361e-03	-4.67	LGALS8 (galectin 8)	protein interactions	3964	169	3	19454	50	PTPRJ,SORL1,ABCC4
9.424e-03	-4.66	negative regulation of cellular component organization	biological process	GO:0051129	709	6	18204	47	SORL1,PICALM,SSH2,NAV3,ARHGAP24,DIP2B
9.426e-03	-4.66	sulfotransferase activity	molecular function	GO:0008146	53	2	18094	50	HS3ST4,CHST11
9.440e-03	-4.66	Signaling events mediated by HDAC Class II	Pathway Interaction DB	hdac_classii_pathway	34	2	2226	10	MEF2C,HDAC9
9.472e-03	-4.66	cellular response to organonitrogen compound	biological process	GO:0071417	505	5	18204	47	SLC8A1,ITPR2,HDAC9,MEF2C,GNAQ
9.530e-03	-4.65	human chr12q24.21	chromosome location	human chr12q24.21	5	1	26134	50	MED13L
9.603e-03	-4.65	negative regulation of protein kinase activity	biological process	GO:0006469	170	3	18204	47	GNAQ,SLC8A1,PTPRJ
9.697e-03	-4.64	cell development	biological process	GO:0048468	2236	12	18204	47	MAP4K4,DSCAM,MEF2C,QKI,KCNQ3,CHST11,DISC1,PICALM,SLC8A1,HDAC9,MEF2A,PTPRJ
9.727e-03	-4.63	NACAEXCHNGR	prints domains	PR01259	3	1	5227	17	SLC8A1
9.727e-03	-4.63	NAHEXCHNGR6	prints domains	PR01088	3	1	5227	17	SLC9A9
9.727e-03	-4.63	INSP3RECEPTR	prints domains	PR00779	3	1	5227	17	ITPR2
9.803e-03	-4.63	central region of growth cone	cellular component	GO:0090724	4	1	19108	47	DISC1
9.803e-03	-4.63	extrinsic component of presynaptic endocytic zone membrane	cellular component	GO:0098894	4	1	19108	47	PICALM
9.862e-03	-4.62	Pre-NOTCH Expression and Processing	REACTOME pathways	R-HSA-1912422	47	2	10285	33	MAML3,MAML2
9.912e-03	-4.61	response to transforming growth factor beta	biological process	GO:0071559	172	3	18204	47	CHST11,MEF2C,ZFHX3
9.988e-03	-4.61	Signaling mediated by p38-alpha and p38-beta	Pathway Interaction DB	p38alphabetadownstreampathway	35	2	2226	10	MEF2A,MEF2C
1.007e-02	-4.60	regulation of cell size	biological process	GO:0008361	173	3	18204	47	DIP2B,DSCAM,DISC1
1.012e-02	-4.59	tibia	COSMIC cancer mutations	tibia	836	7	16828	49	QKI,SLC9A9,FCHSD2,EPB41L2,ST6GALNAC3,ABCC4,PTPRJ
1.017e-02	-4.59	regulation of dendritic spine development	biological process	GO:0060998	59	2	18204	47	MEF2C,DISC1
1.024e-02	-4.58	FBXO41 (F-box protein 41)	protein interactions	150726	4	1	19454	50	DISC1
1.024e-02	-4.58	VGLL2 (vestigial like family member 2)	protein interactions	245806	4	1	19454	50	MEF2C
1.024e-02	-4.58	ZNF615 (zinc finger protein 615)	protein interactions	284370	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	MGAT3 (beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase)	protein interactions	4248	4	1	19454	50	DISC1
1.024e-02	-4.58	ZNF879 (zinc finger protein 879)	protein interactions	345462	4	1	19454	50	ARHGAP24
1.024e-02	-4.58	MRGPRX1 (MAS related GPR family member X1)	protein interactions	259249	4	1	19454	50	GNAQ
1.024e-02	-4.58	PSY3 (Psy3p)	protein interactions	851091	4	1	19454	50	ZFHX3
1.024e-02	-4.58	ZNF749 (zinc finger protein 749)	protein interactions	388567	4	1	19454	50	ARHGAP24
1.025e-02	-4.58	positive regulation of cellular component biogenesis	biological process	GO:0044089	515	5	18204	47	SYNDIG1,PTPRJ,FCHSD2,MAP4K4,NAV3
1.026e-02	-4.58	papillary_renal_cell_carcinoma	COSMIC cancer mutations	papillary_renal_cell_carcinoma	6364	27	16828	49	MED13L,MAML2,DOCK8,MAML3,HDAC9,DIP2B,ARHGAP26,ELMO1,ITPR2,ZSWIM6,SSH2,ZBTB20,DOCK4,SLC8A1,NAV3,ADAM28,SORL1,DSCAM,ZFHX3,PLXDC2,PTPRJ,ANKRD44,ABCC4,MAP4K4,ARHGAP24,PICALM,ARHGAP22
1.026e-02	-4.58	kidney-carcinoma-papillary_renal_cell_carcinoma	COSMIC cancer mutations	kidney-carcinoma-papillary_renal_cell_carcinoma	6364	27	16828	49	HDAC9,MAML3,DIP2B,DOCK8,MAML2,MED13L,DOCK4,SLC8A1,ZBTB20,ZSWIM6,SSH2,ARHGAP26,ELMO1,ITPR2,SORL1,ADAM28,NAV3,MAP4K4,ARHGAP22,PICALM,ARHGAP24,PTPRJ,ANKRD44,PLXDC2,ABCC4,DSCAM,ZFHX3
1.029e-02	-4.58	striatal medium spiny neuron differentiation	biological process	GO:0021773	4	1	18204	47	ZSWIM6
1.029e-02	-4.58	epithelial cell proliferation involved in renal tubule morphogenesis	biological process	GO:2001013	4	1	18204	47	MEF2C
1.029e-02	-4.58	positive regulation of establishment of T cell polarity	biological process	GO:1903905	4	1	18204	47	DOCK8
1.029e-02	-4.58	positive regulation of ER to Golgi vesicle-mediated transport	biological process	GO:1902953	4	1	18204	47	SORL1
1.029e-02	-4.58	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	biological process	GO:0002291	4	1	18204	47	APBB1IP
1.029e-02	-4.58	insulin receptor recycling	biological process	GO:0038020	4	1	18204	47	SORL1
1.029e-02	-4.58	regulation of early endosome to recycling endosome transport	biological process	GO:1902954	4	1	18204	47	SORL1
1.039e-02	-4.57	Rho GTPase cycle	REACTOME pathways	R-HSA-194840	142	3	10285	33	ARHGAP26,ARHGAP22,ARHGAP24
1.041e-02	-4.57	thyroid	COSMIC cancer mutations	thyroid	9867	37	16828	49	DIP2B,HDAC9,MAML3,DOCK8,MAML2,MED13L,MEF2C,SFMBT2,SLC8A1,DOCK4,EPB41L2,SLC9A9,ZFAND3,SSH2,ZSWIM6,ITPR2,FRMD4A,ARHGAP26,ELMO1,GNAQ,SORL1,UBE2E2,APBB1IP,FCHSD2,HS3ST4,CHST11,NAV3,ARHGAP22,PICALM,MAP4K4,ABCC4,PTPRJ,ANKRD44,PLXDC2,ZFHX3,DSCAM,ATP8B4
1.045e-02	-4.56	AP3B1 (adaptor related protein complex 3 subunit beta 1)	protein interactions	8546	176	3	19454	50	EPB41L2,ARHGAP24,MAP4K4
1.048e-02	-4.56	-	gene3d domains	1.20.80.10	51	2	14470	44	EPB41L2,FRMD4A
1.050e-02	-4.56	proteoglycan biosynthetic process	biological process	GO:0030166	60	2	18204	47	CHST11,HS3ST4
1.054e-02	-4.55	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia	156	3	16828	49	MEF2C,TCF12,ARHGAP24
1.074e-02	-4.53	Oxytocin signaling pathway	KEGG pathways	ko04921	152	3	7161	22	MEF2C,ITPR2,GNAQ
1.074e-02	-4.53	Oxytocin signaling pathway	KEGG pathways	hsa04921	152	3	7161	22	MEF2C,ITPR2,GNAQ
1.076e-02	-4.53	GRAF_fam	interpro domains	IPR047234	4	1	18521	50	ARHGAP26
1.076e-02	-4.53	HDAC4/5/7/9	interpro domains	IPR046949	4	1	18521	50	HDAC9
1.076e-02	-4.53	Gprotein_alpha_Q	interpro domains	IPR000654	4	1	18521	50	GNAQ
1.076e-02	-4.53	Band_4	interpro domains	IPR008379	4	1	18521	50	EPB41L2
1.076e-02	-4.53	PH_GRAF	interpro domains	IPR047225	4	1	18521	50	ARHGAP26
1.076e-02	-4.53	ANTH_dom	interpro domains	IPR011417	4	1	18521	50	PICALM
1.076e-02	-4.53	SAB_dom	interpro domains	IPR007477	4	1	18521	50	EPB41L2
1.076e-02	-4.53	ZSWIM4-8_C	interpro domains	IPR048370	4	1	18521	50	ZSWIM6
1.076e-02	-4.53	CUPID	interpro domains	IPR021774	4	1	18521	50	FRMD4A
1.076e-02	-4.53	DEK_C	interpro domains	IPR014876	4	1	18521	50	SSH2
1.076e-02	-4.53	PTBP2 (polypyrimidine tract binding protein 2)	protein interactions	58155	61	2	19454	50	QKI,UBE2E2
1.078e-02	-4.53	nodular	COSMIC cancer mutations	nodular	1515	10	16828	49	ARHGAP26,ZFHX3,ANKRD44,DOCK8,DISC1,SORL1,DIP2B,SFMBT2,GNAQ,SLC8A1
1.079e-02	-4.53	glycoprotein metabolic process	biological process	GO:0009100	335	4	18204	47	ST6GAL1,ST6GALNAC3,CHST11,HS3ST4
1.097e-02	-4.51	ZSWIM4-8_C	pfam domains	PF21055	4	1	17795	49	ZSWIM6
1.097e-02	-4.51	CUPID	pfam domains	PF11819	4	1	17795	49	FRMD4A
1.097e-02	-4.51	SAB	pfam domains	PF04382	4	1	17795	49	EPB41L2
1.097e-02	-4.51	4_1_CTD	pfam domains	PF05902	4	1	17795	49	EPB41L2
1.097e-02	-4.51	ANTH	pfam domains	PF07651	4	1	17795	49	PICALM
1.097e-02	-4.51	DEK_C	pfam domains	PF08766	4	1	17795	49	SSH2
1.101e-02	-4.51	histone H3K deacetylase activity	molecular function	GO:0141050	4	1	18094	50	HDAC9
1.101e-02	-4.51	ATPase-coupled organic acid transmembrane transporter activity	molecular function	GO:0033283	4	1	18094	50	ABCC4
1.101e-02	-4.51	ATPase-coupled carboxylic acid transmembrane transporter activity	molecular function	GO:0033284	4	1	18094	50	ABCC4
1.101e-02	-4.51	ABC-type bile acid transporter activity	molecular function	GO:0015432	4	1	18094	50	ABCC4
1.101e-02	-4.51	ISG15 transferase activity	molecular function	GO:0042296	4	1	18094	50	UBE2E2
1.101e-02	-4.51	ATPase-coupled monocarboxylic acid transmembrane transporter activity	molecular function	GO:0033285	4	1	18094	50	ABCC4
1.101e-02	-4.51	chondroitin 4-sulfotransferase activity	molecular function	GO:0047756	4	1	18094	50	CHST11
1.110e-02	-4.50	DTX3L (deltex E3 ubiquitin ligase 3L)	protein interactions	151636	62	2	19454	50	UBE2E2,EPB41L2
1.110e-02	-4.50	EPHA4 (EPH receptor A4)	protein interactions	2043	180	3	19454	50	TBC1D22A,DIP2B,MAP4K4
1.110e-02	-4.50	MYOD1 (myogenic differentiation 1)	protein interactions	4654	180	3	19454	50	TCF12,MEF2C,MEF2A
1.111e-02	-4.50	homeostatic process	biological process	GO:0042592	1456	9	18204	47	MEF2C,SLC9A9,PTPRJ,HDAC9,DISC1,SORL1,ZBTB20,SLC8A1,PICALM
1.116e-02	-4.50	stereocilium bundle	cellular component	GO:0032421	65	2	19108	47	FCHSD2,DOCK4
1.118e-02	-4.49	parietal_lobe	COSMIC cancer mutations	parietal_lobe	55	2	16828	49	QKI,GNAQ
1.125e-02	-4.49	skin-trunk-malignant_melanoma-nodular	COSMIC cancer mutations	skin-trunk-malignant_melanoma-nodular	1291	9	16828	49	DOCK8,DISC1,SORL1,SFMBT2,DIP2B,SLC8A1,ARHGAP26,ZFHX3,ANKRD44
1.138e-02	-4.48	negative regulation of kinase activity	biological process	GO:0033673	181	3	18204	47	GNAQ,SLC8A1,PTPRJ
1.138e-02	-4.48	head_neck	COSMIC cancer mutations	head_neck	15361	49	16828	49	SYNDIG1,PICALM,ST6GALNAC3,ZFHX3,ADAM28,APBB1IP,HS3ST4,NAV3,SLC9A9,TBC1D22A,ITPR2,FRMD4A,MAML3,DIP2B,DOCK8,MAML2,MEF2C,ST6GAL1,MAP4K4,ARHGAP22,ARHGAP24,PTPRJ,ANKRD44,PLXDC2,ABCC4,DSCAM,ATP8B4,GNAQ,FCHSD2,DISC1,SORL1,UBE2E2,CHST11,DOCK4,EPB41L2,SFMBT2,SLC8A1,ZBTB20,ZFAND3,ZSWIM6,SSH2,MEF2A,ELMO1,ARHGAP26,HDAC9,KCNQ3,QKI,MED13L,TCF12
1.144e-02	-4.47	Calcium Regulation in the Cardiac Cell	WikiPathways	WP536	151	3	5310	17	SLC8A1,GNAQ,ITPR2
1.144e-02	-4.47	DEK_C	prosite domains	PS51998	4	1	12186	35	SSH2
1.151e-02	-4.46	blood vessel development	biological process	GO:0001568	530	5	18204	47	MEF2C,ARHGAP22,QKI,ARHGAP24,PTPRJ
1.153e-02	-4.46	regulation of focal adhesion assembly	biological process	GO:0051893	63	2	18204	47	MAP4K4,PTPRJ
1.153e-02	-4.46	regulation of cell-substrate junction assembly	biological process	GO:0090109	63	2	18204	47	PTPRJ,MAP4K4
1.160e-02	-4.46	central_nervous_system-occipital_lobe-other-ganglioglioma	COSMIC cancer mutations	central_nervous_system-occipital_lobe-other-ganglioglioma	4	1	16828	49	GNAQ
1.160e-02	-4.46	skin-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-benign_melanocytic_nevus-blue	4	1	16828	49	GNAQ
1.160e-02	-4.46	skin-elbow-benign_melanocytic_nevus-Spitz	COSMIC cancer mutations	skin-elbow-benign_melanocytic_nevus-Spitz	4	1	16828	49	GNAQ
1.160e-02	-4.46	soft_tissue-nerve_sheath-schwannoma-melanotic	COSMIC cancer mutations	soft_tissue-nerve_sheath-schwannoma-melanotic	4	1	16828	49	GNAQ
1.160e-02	-4.46	skin-scalp-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-scalp-benign_melanocytic_nevus-blue	4	1	16828	49	GNAQ
1.160e-02	-4.46	skin-flank-benign_melanocytic_nevus	COSMIC cancer mutations	skin-flank-benign_melanocytic_nevus	4	1	16828	49	GNAQ
1.160e-02	-4.46	skin-malignant_melanoma-spitzoid	COSMIC cancer mutations	skin-malignant_melanoma-spitzoid	4	1	16828	49	GNAQ
1.167e-02	-4.45	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified	162	3	16828	49	DIP2B,ITPR2,ATP8B4
1.195e-02	-4.43	PDE4DIP (phosphodiesterase 4D interacting protein)	protein interactions	9659	185	3	19454	50	DSCAM,DISC1,FCHSD2
1.196e-02	-4.43	LDLa	smart domains	SM00192	45	2	9717	36	SORL1,LDLRAD4
1.207e-02	-4.42	cellular response to metal ion	biological process	GO:0071248	185	3	18204	47	KCNQ3,MEF2A,MEF2C
1.211e-02	-4.41	Platelet activation, signaling and aggregation	REACTOME pathways	R-HSA-76002	282	4	10285	33	ITPR2,APBB1IP,GNAQ,ABCC4
1.213e-02	-4.41	molecular adaptor activity	molecular function	GO:0060090	1138	8	18094	50	QKI,DISC1,SFMBT2,HDAC9,MAML2,MAML3,MED13L,FRMD4A
1.214e-02	-4.41	transcription coregulator activity	molecular function	GO:0003712	501	5	18094	50	MAML2,MAML3,SFMBT2,MED13L,HDAC9
1.216e-02	-4.41	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma	476	5	16828	49	ZSWIM6,MAML2,DSCAM,ZFHX3,ZFAND3
1.224e-02	-4.40	perinucleolar compartment	cellular component	GO:0097356	5	1	19108	47	SORL1
1.224e-02	-4.40	neurofibrillary tangle	cellular component	GO:0097418	5	1	19108	47	PICALM
1.250e-02	-4.38	KATNA1 (katanin catalytic subunit A1)	protein interactions	11104	66	2	19454	50	LDLRAD4,ARHGAP24
1.250e-02	-4.38	CFAP206 (cilia and flagella associated protein 206)	protein interactions	154313	66	2	19454	50	TCF12,DISC1
1.260e-02	-4.37	endosome membrane	cellular component	GO:0010008	569	5	19108	47	SLC9A9,LDLRAD4,SYNDIG1,SORL1,ARHGAP26
1.260e-02	-4.37	cardiac muscle cell development	biological process	GO:0055013	66	2	18204	47	MEF2A,SLC8A1
1.262e-02	-4.37	bone-pelvis-chondrosarcoma	COSMIC cancer mutations	bone-pelvis-chondrosarcoma	311	4	16828	49	MAML3,SYNDIG1,ZFHX3,NAV3
1.266e-02	-4.37	peripheral_T_cell_lymphoma_unspecified	COSMIC cancer mutations	peripheral_T_cell_lymphoma_unspecified	167	3	16828	49	ITPR2,ATP8B4,DIP2B
1.275e-02	-4.36	Oxytocin signaling	WikiPathways	WP2889	4	1	5310	17	GNAQ
1.275e-02	-4.36	Serotonin Receptor 2 and STAT3 Signaling	WikiPathways	WP733	4	1	5310	17	GNAQ
1.278e-02	-4.36	B cell activation	biological process	GO:0042113	189	3	18204	47	MEF2C,HDAC9,PTPRJ
1.279e-02	-4.36	ZNF571 (zinc finger protein 571)	protein interactions	51276	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	ORF48 (ORF48)	protein interactions	4961458	5	1	19454	50	ANKRD44
1.279e-02	-4.36	ASTN1 (astrotactin 1)	protein interactions	460	5	1	19454	50	DSCAM
1.279e-02	-4.36	ZNF836 (zinc finger protein 836)	protein interactions	162962	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	SLC16A14 (solute carrier family 16 member 14)	protein interactions	151473	5	1	19454	50	GNAQ
1.279e-02	-4.36	POU2F3 (POU class 2 homeobox 3)	protein interactions	25833	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	TRPM6 (transient receptor potential cation channel subfamily M member 6)	protein interactions	140803	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	ZNF93 (zinc finger protein 93)	protein interactions	81931	5	1	19454	50	ARHGAP24
1.279e-02	-4.36	HOXC12 (homeobox C12)	protein interactions	3228	5	1	19454	50	SORL1
1.284e-02	-4.35	positive regulation of the force of heart contraction	biological process	GO:0098735	5	1	18204	47	SLC8A1
1.284e-02	-4.35	psychomotor behavior	biological process	GO:0036343	5	1	18204	47	KCNQ3
1.284e-02	-4.35	positive regulation of Fc receptor mediated stimulatory signaling pathway	biological process	GO:0060369	5	1	18204	47	PTPRJ
1.284e-02	-4.35	negative regulation of triglyceride catabolic process	biological process	GO:0010897	5	1	18204	47	SORL1
1.284e-02	-4.35	negative regulation of Rac protein signal transduction	biological process	GO:0035021	5	1	18204	47	ARHGAP24
1.284e-02	-4.35	protein retention in Golgi apparatus	biological process	GO:0045053	5	1	18204	47	SORL1
1.284e-02	-4.35	prostaglandin secretion	biological process	GO:0032310	5	1	18204	47	ABCC4
1.293e-02	-4.35	Myometrial Relaxation and Contraction Pathways	WikiPathways	WP289	158	3	5310	17	SLC8A1,GNAQ,ITPR2
1.295e-02	-4.35	GPROTEINAQ	prints domains	PR00442	4	1	5227	17	GNAQ
1.302e-02	-4.34	ovary	COSMIC cancer mutations	ovary	14770	48	16828	49	ZBTB20,SLC9A9,ZFAND3,SFMBT2,SLC8A1,DOCK4,EPB41L2,ITPR2,FRMD4A,MEF2A,ARHGAP26,ELMO1,SSH2,TBC1D22A,ZSWIM6,KCNQ3,QKI,DOCK8,DIP2B,HDAC9,MAML3,MEF2C,TCF12,MAML2,MED13L,ARHGAP22,ARHGAP24,PICALM,MAP4K4,ST6GAL1,SYNDIG1,DSCAM,ZFHX3,ATP8B4,ABCC4,ST6GALNAC3,PTPRJ,ANKRD44,PLXDC2,SORL1,ADAM28,APBB1IP,UBE2E2,FCHSD2,GNAQ,CHST11,NAV3,HS3ST4
1.303e-02	-4.34	negative regulation of multicellular organismal process	biological process	GO:0051241	1237	8	18204	47	SORL1,LDLRAD4,DOCK4,MEF2C,NAV3,QKI,HDAC9,DIP2B
1.304e-02	-4.34	SH3_9	pfam domains	PF14604	63	2	17795	49	ARHGAP26,FCHSD2
1.305e-02	-4.34	actin cytoskeleton organization	biological process	GO:0030036	547	5	18204	47	EPB41L2,SSH2,ARHGAP26,ELMO1,MEF2A
1.320e-02	-4.33	MED17 (mediator complex subunit 17)	protein interactions	9440	192	3	19454	50	MED13L,PICALM,QKI
1.333e-02	-4.32	regulation of neuron differentiation	biological process	GO:0045664	192	3	18204	47	MEF2C,ZFHX3,TCF12
1.334e-02	-4.32	regulation of cell-substrate junction organization	biological process	GO:0150116	68	2	18204	47	MAP4K4,PTPRJ
1.334e-02	-4.32	vasculature development	biological process	GO:0001944	550	5	18204	47	MEF2C,ARHGAP24,QKI,ARHGAP22,PTPRJ
1.343e-02	-4.31	Sortilin_C	interpro domains	IPR031777	5	1	18521	50	SORL1
1.343e-02	-4.31	DOCK_N_sub1	interpro domains	IPR042455	5	1	18521	50	DOCK4
1.343e-02	-4.31	VPS10	interpro domains	IPR006581	5	1	18521	50	SORL1
1.343e-02	-4.31	PH_APBB1IP	interpro domains	IPR039665	5	1	18521	50	APBB1IP
1.343e-02	-4.31	DOCK_N	interpro domains	IPR032376	5	1	18521	50	DOCK4
1.343e-02	-4.31	SLED_sf	interpro domains	IPR038348	5	1	18521	50	SFMBT2
1.343e-02	-4.31	K_chnl_volt-dep_KCNQ_C	interpro domains	IPR013821	5	1	18521	50	KCNQ3
1.343e-02	-4.31	BBP-like	interpro domains	IPR045071	5	1	18521	50	QKI
1.343e-02	-4.31	K_chnl_volt-dep_KCNQ	interpro domains	IPR003937	5	1	18521	50	KCNQ3
1.343e-02	-4.31	GRB/APBB1IP	interpro domains	IPR039664	5	1	18521	50	APBB1IP
1.343e-02	-4.31	SLED	interpro domains	IPR021987	5	1	18521	50	SFMBT2
1.343e-02	-4.31	Sortilin_N	interpro domains	IPR031778	5	1	18521	50	SORL1
1.343e-02	-4.31	Ubiquitin-like_domsf	interpro domains	IPR029071	184	3	18521	50	FRMD4A,APBB1IP,EPB41L2
1.351e-02	-4.30	cellular response to xenobiotic stimulus	biological process	GO:0071466	193	3	18204	47	MEF2C,ABCC4,KCNQ3
1.357e-02	-4.30	inclusion body	cellular component	GO:0016234	72	2	19108	47	PICALM,SFMBT2
1.362e-02	-4.30	intracellular signal transduction	biological process	GO:0035556	1505	9	18204	47	DOCK8,MEF2C,MEF2A,ELMO1,DISC1,MAP4K4,DOCK4,SLC8A1,ITPR2
1.367e-02	-4.29	neoplasm	COSMIC cancer mutations	neoplasm	14787	48	16828	49	MEF2C,MAML2,DOCK8,MAML3,DIP2B,ITPR2,FRMD4A,TBC1D22A,SLC9A9,NAV3,HS3ST4,ADAM28,APBB1IP,ZFHX3,ST6GALNAC3,SYNDIG1,PICALM,MED13L,TCF12,KCNQ3,QKI,HDAC9,MEF2A,ELMO1,ARHGAP26,ZSWIM6,SSH2,ZBTB20,ZFAND3,EPB41L2,DOCK4,SFMBT2,SLC8A1,CHST11,FCHSD2,SORL1,UBE2E2,GNAQ,DSCAM,ATP8B4,ANKRD44,PTPRJ,PLXDC2,ABCC4,ST6GAL1,MAP4K4,ARHGAP22,ARHGAP24
1.369e-02	-4.29	SLED	pfam domains	PF12140	5	1	17795	49	SFMBT2
1.369e-02	-4.29	DOCK_N	pfam domains	PF16172	5	1	17795	49	DOCK4
1.369e-02	-4.29	Sortilin_C	pfam domains	PF15901	5	1	17795	49	SORL1
1.369e-02	-4.29	KCNQ_channel	pfam domains	PF03520	5	1	17795	49	KCNQ3
1.369e-02	-4.29	DMAP_binding	pfam domains	PF06464	5	1	17795	49	DIP2B
1.369e-02	-4.29	Sortilin-Vps10	pfam domains	PF15902	5	1	17795	49	SORL1
1.374e-02	-4.29	glutathione transmembrane transporter activity	molecular function	GO:0034634	5	1	18094	50	ABCC4
1.374e-02	-4.29	N-acetylgalactosamine 4-O-sulfotransferase activity	molecular function	GO:0001537	5	1	18094	50	CHST11
1.374e-02	-4.29	guanine nucleotide transmembrane transporter activity	molecular function	GO:0001409	5	1	18094	50	ABCC4
1.375e-02	-4.29	skin-upper_back-malignant_melanoma	COSMIC cancer mutations	skin-upper_back-malignant_melanoma	319	4	16828	49	PTPRJ,KCNQ3,ATP8B4,ELMO1
1.380e-02	-4.28	Ion homeostasis	REACTOME pathways	R-HSA-5578775	56	2	10285	33	ITPR2,SLC8A1
1.389e-02	-4.28	Cardiac Hypertrophic Response	WikiPathways	WP2795	57	2	5310	17	MEF2A,HDAC9
1.399e-02	-4.27	CTDNEP1 (CTD nuclear envelope phosphatase 1)	protein interactions	23399	70	2	19454	50	ITPR2,PLXDC2
1.409e-02	-4.26	cardiac conduction	biological process	GO:0061337	70	2	18204	47	MEF2A,SLC8A1
1.413e-02	-4.26	lower_leg	COSMIC cancer mutations	lower_leg	174	3	16828	49	ADAM28,GNAQ,PTPRJ
1.414e-02	-4.26	recycling endosome	cellular component	GO:0055037	206	3	19108	47	SLC9A9,FCHSD2,SORL1
1.414e-02	-4.26	GAR1 (GAR1 ribonucleoprotein)	protein interactions	54433	197	3	19454	50	ARHGAP22,DOCK4,MAP4K4
1.418e-02	-4.26	liver-carcinoma-hepatocellular_carcinoma	COSMIC cancer mutations	liver-carcinoma-hepatocellular_carcinoma	14800	48	16828	49	DSCAM,ATP8B4,PTPRJ,ANKRD44,PLXDC2,ABCC4,ST6GAL1,MAP4K4,ARHGAP22,ARHGAP24,CHST11,DISC1,SORL1,UBE2E2,GNAQ,MEF2A,ARHGAP26,ELMO1,ZSWIM6,SSH2,ZBTB20,ZFAND3,DOCK4,EPB41L2,SFMBT2,SLC8A1,MED13L,TCF12,KCNQ3,QKI,HDAC9,ZFHX3,ST6GALNAC3,SYNDIG1,PICALM,NAV3,HS3ST4,ADAM28,APBB1IP,ITPR2,FRMD4A,TBC1D22A,SLC9A9,MEF2C,MAML2,DOCK8,MAML3,DIP2B
1.418e-02	-4.26	hepatocellular_carcinoma	COSMIC cancer mutations	hepatocellular_carcinoma	14800	48	16828	49	SLC9A9,FRMD4A,ITPR2,TBC1D22A,DOCK8,MAML3,DIP2B,MEF2C,MAML2,SYNDIG1,PICALM,ZFHX3,ST6GALNAC3,APBB1IP,ADAM28,NAV3,HS3ST4,ZFAND3,ZBTB20,EPB41L2,DOCK4,SLC8A1,SFMBT2,ARHGAP26,ELMO1,MEF2A,ZSWIM6,SSH2,QKI,KCNQ3,HDAC9,MED13L,TCF12,ST6GAL1,MAP4K4,ARHGAP24,ARHGAP22,ATP8B4,DSCAM,PLXDC2,ANKRD44,PTPRJ,ABCC4,UBE2E2,SORL1,DISC1,GNAQ,CHST11
1.432e-02	-4.25	Long-term depression	KEGG pathways	hsa04730	60	2	7161	22	GNAQ,ITPR2
1.432e-02	-4.25	Long-term depression	KEGG pathways	ko04730	60	2	7161	22	ITPR2,GNAQ
1.448e-02	-4.24	skin-forearm-benign_melanocytic_nevus-Spitz	COSMIC cancer mutations	skin-forearm-benign_melanocytic_nevus-Spitz	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-foot-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-foot-benign_melanocytic_nevus-melanocytic_tumour	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-forearm-benign_melanocytic_nevus	COSMIC cancer mutations	skin-forearm-benign_melanocytic_nevus	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-ankle-benign_melanocytic_nevus-Spitz	COSMIC cancer mutations	skin-ankle-benign_melanocytic_nevus-Spitz	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-lower_back-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-lower_back-benign_melanocytic_nevus-blue	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-arm-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-arm-benign_melanocytic_nevus-blue	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-scalp-benign_melanocytic_nevus	COSMIC cancer mutations	skin-scalp-benign_melanocytic_nevus	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-face-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-face-benign_melanocytic_nevus-melanocytic_tumour	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-face-benign_melanocytic_nevus	COSMIC cancer mutations	skin-face-benign_melanocytic_nevus	5	1	16828	49	GNAQ
1.448e-02	-4.24	skin-buttock-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-buttock-benign_melanocytic_nevus-melanocytic_tumour	5	1	16828	49	GNAQ
1.448e-02	-4.24	central_nervous_system-brainstem-other-ganglioglioma	COSMIC cancer mutations	central_nervous_system-brainstem-other-ganglioglioma	5	1	16828	49	GNAQ
1.455e-02	-4.23	Activation of PKC Through G Protein-Coupled Receptor	SMPDB pathways	SMP0000749	4	1	1369	5	GNAQ
1.466e-02	-4.22	cardiac muscle tissue development	biological process	GO:0048738	199	3	18204	47	SLC8A1,MEF2A,MEF2C
1.467e-02	-4.22	external side of apical plasma membrane	cellular component	GO:0098591	6	1	19108	47	ABCC4
1.467e-02	-4.22	extrinsic component of presynaptic membrane	cellular component	GO:0098888	6	1	19108	47	PICALM
1.467e-02	-4.22	platelet dense granule membrane	cellular component	GO:0031088	6	1	19108	47	ABCC4
1.476e-02	-4.22	DGCR6 (DiGeorge syndrome critical region gene 6)	protein interactions	8214	72	2	19454	50	DOCK8,TCF12
1.477e-02	-4.22	endosome	cellular component	GO:0005768	1067	7	19108	47	SYNDIG1,SLC9A9,FCHSD2,PICALM,LDLRAD4,SORL1,ARHGAP26
1.486e-02	-4.21	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	biological process	GO:0090101	200	3	18204	47	SORL1,LDLRAD4,CHST11
1.487e-02	-4.21	PH	smart domains	SM00233	259	4	9717	36	ARHGAP22,ARHGAP26,APBB1IP,ARHGAP24
1.491e-02	-4.21	DBN1 (drebrin 1)	protein interactions	1627	370	4	19454	50	SSH2,PICALM,DISC1,ARHGAP24
1.511e-02	-4.19	SLED domain	gene3d domains	3.90.1150.190	5	1	14470	44	SFMBT2
1.511e-02	-4.19	-	gene3d domains	6.10.140.1910	5	1	14470	44	KCNQ3
1.511e-02	-4.19	-	gene3d domains	3.30.60.270	5	1	14470	44	SORL1
1.511e-02	-4.19	Dedicator of cytokinesis N-terminal subdomain	gene3d domains	1.20.1270.350	5	1	14470	44	DOCK4
1.511e-02	-4.19	-	gene3d domains	2.10.70.80	5	1	14470	44	SORL1
1.515e-02	-4.19	AGAP3 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 3)	protein interactions	116988	73	2	19454	50	ARHGAP24,ARHGAP22
1.518e-02	-4.19	B41	smart domains	SM00295	51	2	9717	36	EPB41L2,FRMD4A
1.520e-02	-4.19	skin-scalp-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-scalp-carcinoma-squamous_cell_carcinoma	1596	10	16828	49	SLC8A1,SFMBT2,SYNDIG1,SORL1,KCNQ3,CHST11,ZFHX3,DSCAM,ELMO1,NAV3
1.524e-02	-4.18	adrenal_gland	COSMIC cancer mutations	adrenal_gland	2628	14	16828	49	ST6GAL1,DOCK4,ZBTB20,PTPRJ,ABCC4,MEF2A,ELMO1,FRMD4A,ATP8B4,HDAC9,GNAQ,DIP2B,DOCK8,MAML2
1.526e-02	-4.18	regulation of protein polymerization	biological process	GO:0032271	202	3	18204	47	NAV3,FCHSD2,SSH2
1.526e-02	-4.18	cardiac cell development	biological process	GO:0055006	73	2	18204	47	SLC8A1,MEF2A
1.526e-02	-4.18	vasculogenesis	biological process	GO:0001570	73	2	18204	47	QKI,PTPRJ
1.526e-02	-4.18	regulation of insulin receptor signaling pathway	biological process	GO:0046626	73	2	18204	47	PTPRJ,SORL1
1.530e-02	-4.18	intracellular membrane-bounded organelle	cellular component	GO:0043231	12479	38	19108	47	SLC9A9,HS3ST4,PICALM,EPB41L2,ZBTB20,DOCK4,SFMBT2,CHST11,DISC1,ZFHX3,ATP8B4,SSH2,ST6GAL1,MED13L,MEF2A,PTPRJ,MAML2,TCF12,KCNQ3,HDAC9,ARHGAP22,SYNDIG1,MEF2C,SLC8A1,NAV3,ABCC4,SORL1,MAML3,ST6GALNAC3,ITPR2,ADAM28,QKI,FCHSD2,DIP2B,LDLRAD4,UBE2E2,ARHGAP26,GNAQ
1.532e-02	-4.18	Dock11 (dedicator of cytokinesis 11)	protein interactions	75974	6	1	19454	50	EPB41L2
1.532e-02	-4.18	IL1RAPL1 (interleukin 1 receptor accessory protein like 1)	protein interactions	11141	6	1	19454	50	ARHGAP22
1.532e-02	-4.18	ZNF713 (zinc finger protein 713)	protein interactions	349075	6	1	19454	50	SORL1
1.532e-02	-4.18	S1PR3 (sphingosine-1-phosphate receptor 3)	protein interactions	1903	6	1	19454	50	GNAQ
1.532e-02	-4.18	ZNF311 (zinc finger protein 311)	protein interactions	282890	6	1	19454	50	ARHGAP24
1.532e-02	-4.18	KCNN1 (potassium calcium-activated channel subfamily N member 1)	protein interactions	3780	6	1	19454	50	DSCAM
1.532e-02	-4.18	DAZ4 (deleted in azoospermia 4)	protein interactions	57135	6	1	19454	50	QKI
1.532e-02	-4.18	HRD1 (E3 ubiquitin-protein ligase HRD1)	protein interactions	854149	6	1	19454	50	UBE2E2
1.532e-02	-4.18	PBP2 (Pbp2p)	protein interactions	852533	6	1	19454	50	QKI
1.532e-02	-4.18	AKR1C4 (aldo-keto reductase family 1 member C4)	protein interactions	1109	6	1	19454	50	PLXDC2
1.539e-02	-4.17	positive regulation of peptidyl-lysine acetylation	biological process	GO:2000758	6	1	18204	47	DIP2B
1.539e-02	-4.17	mitochondrial depolarization	biological process	GO:0051882	6	1	18204	47	KCNQ3
1.539e-02	-4.17	radial glia-guided pyramidal neuron migration	biological process	GO:0140650	6	1	18204	47	DISC1
1.539e-02	-4.17	positive regulation of protein localization to cell cortex	biological process	GO:1904778	6	1	18204	47	EPB41L2
1.539e-02	-4.17	regulation of focal adhesion disassembly	biological process	GO:0120182	6	1	18204	47	MAP4K4
1.539e-02	-4.17	positive regulation of focal adhesion disassembly	biological process	GO:0120183	6	1	18204	47	MAP4K4
1.539e-02	-4.17	regulation of establishment of T cell polarity	biological process	GO:1903903	6	1	18204	47	DOCK8
1.539e-02	-4.17	peptidyl-lysine deacetylation	biological process	GO:0034983	6	1	18204	47	HDAC9
1.539e-02	-4.17	ISG15-protein conjugation	biological process	GO:0032020	6	1	18204	47	UBE2E2
1.539e-02	-4.17	post-embryonic animal morphogenesis	biological process	GO:0009886	6	1	18204	47	DSCAM
1.541e-02	-4.17	clathrin-coated pit	cellular component	GO:0005905	77	2	19108	47	PICALM,FCHSD2
1.547e-02	-4.17	heart development	biological process	GO:0007507	571	5	18204	47	PTPRJ,SLC8A1,MEF2A,HDAC9,MEF2C
1.570e-02	-4.15	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	COSMIC cancer mutations	central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype	181	3	16828	49	ARHGAP26,ELMO1,ZFHX3
1.573e-02	-4.15	Signaling by BRAF and RAF fusions	REACTOME pathways	R-HSA-6802952	60	2	10285	33	APBB1IP,QKI
1.582e-02	-4.15	TRIM25 (tripartite motif containing 25)	protein interactions	7706	2387	12	19454	50	CHST11,GNAQ,SSH2,TCF12,ZFAND3,PTPRJ,DIP2B,MAP4K4,MED13L,ABCC4,ZFHX3,PICALM
1.587e-02	-4.14	striated muscle tissue development	biological process	GO:0014706	205	3	18204	47	MEF2C,MEF2A,SLC8A1
1.593e-02	-4.14	WNT_subtype	COSMIC cancer mutations	WNT_subtype	182	3	16828	49	ZFHX3,ELMO1,ARHGAP26
1.594e-02	-4.14	JUND (JunD proto-oncogene, AP-1 transcription factor subunit)	protein interactions	3727	75	2	19454	50	MEF2A,ARHGAP22
1.594e-02	-4.14	SSH3 (slingshot protein phosphatase 3)	protein interactions	54961	75	2	19454	50	SSH2,ARHGAP24
1.600e-02	-4.13	other	COSMIC cancer mutations	other	14843	48	16828	49	ZFAND3,ZBTB20,DOCK4,EPB41L2,SLC8A1,SFMBT2,ARHGAP26,ELMO1,MEF2A,ZSWIM6,SSH2,QKI,KCNQ3,HDAC9,MED13L,TCF12,ST6GAL1,MAP4K4,ARHGAP24,ARHGAP22,ATP8B4,DSCAM,PLXDC2,ANKRD44,PTPRJ,ABCC4,FCHSD2,UBE2E2,SORL1,GNAQ,CHST11,SLC9A9,FRMD4A,ITPR2,TBC1D22A,DOCK8,MAML3,DIP2B,MEF2C,MAML2,SYNDIG1,PICALM,ZFHX3,ST6GALNAC3,APBB1IP,ADAM28,NAV3,HS3ST4
1.606e-02	-4.13	regulation of cellular response to insulin stimulus	biological process	GO:1900076	75	2	18204	47	PTPRJ,SORL1
1.606e-02	-4.13	regulation of behavior	biological process	GO:0050795	75	2	18204	47	ZFHX3,MEF2C
1.609e-02	-4.13	DOCK_C/D_N	interpro domains	IPR021816	6	1	18521	50	DOCK8
1.609e-02	-4.13	RIH_dom	interpro domains	IPR000699	6	1	18521	50	ITPR2
1.609e-02	-4.13	Ryanodine_IP3_receptor	interpro domains	IPR015925	6	1	18521	50	ITPR2
1.609e-02	-4.13	Ins145_P3_rcpt	interpro domains	IPR014821	6	1	18521	50	ITPR2
1.609e-02	-4.13	RyR/IP3R_RIH_dom_sf	interpro domains	IPR035910	6	1	18521	50	ITPR2
1.609e-02	-4.13	DMAP1-bd	interpro domains	IPR010506	6	1	18521	50	DIP2B
1.609e-02	-4.13	RIH_assoc-dom	interpro domains	IPR013662	6	1	18521	50	ITPR2
1.609e-02	-4.13	ELMO_dom	interpro domains	IPR006816	6	1	18521	50	ELMO1
1.616e-02	-4.13	KCNQCHANNEL	prints domains	PR01459	5	1	5227	17	KCNQ3
1.630e-02	-4.12	Notch Signaling Pathway	WikiPathways	WP61	62	2	5310	17	MAML2,MAML3
1.635e-02	-4.11	KIF5A (kinesin family member 5A)	protein interactions	3798	76	2	19454	50	MAP4K4,DSCAM
1.635e-02	-4.11	PGM3 (phosphoglucomutase 3)	protein interactions	5238	76	2	19454	50	ARHGAP24,DISC1
1.635e-02	-4.11	CYP1A1 (cytochrome P450 family 1 subfamily A member 1)	protein interactions	1543	76	2	19454	50	PICALM,QKI
1.641e-02	-4.11	ELMO_CED12	pfam domains	PF04727	6	1	17795	49	ELMO1
1.641e-02	-4.11	RYDR_ITPR	pfam domains	PF01365	6	1	17795	49	ITPR2
1.641e-02	-4.11	RIH_assoc	pfam domains	PF08454	6	1	17795	49	ITPR2
1.641e-02	-4.11	DOCK_C-D_N	pfam domains	PF11878	6	1	17795	49	DOCK8
1.641e-02	-4.11	Ins145_P3_rec	pfam domains	PF08709	6	1	17795	49	ITPR2
1.645e-02	-4.11	cellular response to nitrogen compound	biological process	GO:1901699	580	5	18204	47	GNAQ,MEF2C,HDAC9,SLC8A1,ITPR2
1.647e-02	-4.11	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	molecular function	GO:0001665	6	1	18094	50	ST6GALNAC3
1.647e-02	-4.11	creatine kinase activity	molecular function	GO:0004111	6	1	18094	50	MAP4K4
1.647e-02	-4.11	chondroitin sulfotransferase activity	molecular function	GO:0034481	6	1	18094	50	CHST11
1.647e-02	-4.11	transferase activity, transferring sulphur-containing groups	molecular function	GO:0016782	71	2	18094	50	CHST11,HS3ST4
1.656e-02	-4.10	intracellular chemical homeostasis	biological process	GO:0055082	581	5	18204	47	SLC8A1,PICALM,DISC1,SLC9A9,ZBTB20
1.656e-02	-4.10	somatodendritic compartment	cellular component	GO:0036477	842	6	19108	47	SORL1,DSCAM,DIP2B,SLC8A1,PICALM,SYNDIG1
1.660e-02	-4.10	negative regulation of cell migration	biological process	GO:0030336	381	4	18204	47	PTPRJ,MEF2C,NAV3,LDLRAD4
1.667e-02	-4.09	Renin secretion	KEGG pathways	ko04924	65	2	7161	22	ITPR2,GNAQ
1.667e-02	-4.09	Renin secretion	KEGG pathways	hsa04924	65	2	7161	22	GNAQ,ITPR2
1.670e-02	-4.09	regulation of chemotaxis	biological process	GO:0050920	209	3	18204	47	PTPRJ,ST6GAL1,DSCAM
1.674e-02	-4.09	buttock	COSMIC cancer mutations	buttock	68	2	16828	49	PTPRJ,GNAQ
1.675e-02	-4.09	skin-head_neck-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-head_neck-malignant_melanoma-superficial_spreading	923	7	16828	49	KCNQ3,APBB1IP,DIP2B,TCF12,ABCC4,SLC8A1,PLXDC2
1.676e-02	-4.09	FKBP2 (FKBP prolyl isomerase 2)	protein interactions	2286	77	2	19454	50	QKI,EPB41L2
1.688e-02	-4.08	regulation of synaptic transmission, glutamatergic	biological process	GO:0051966	77	2	18204	47	MEF2C,DISC1
1.688e-02	-4.08	positive regulation of axonogenesis	biological process	GO:0050772	77	2	18204	47	DISC1,DSCAM
1.688e-02	-4.08	positive regulation of small GTPase mediated signal transduction	biological process	GO:0051057	77	2	18204	47	MAP4K4,PICALM
1.705e-02	-4.07	Tyr_Pase_AS	interpro domains	IPR016130	74	2	18521	50	PTPRJ,SSH2
1.711e-02	-4.07	ELMO	prosite domains	PS51335	6	1	12186	35	ELMO1
1.711e-02	-4.07	DMAP1_BIND	prosite domains	PS51912	6	1	12186	35	DIP2B
1.712e-02	-4.07	cellular response to chemical stimulus	biological process	GO:0070887	2411	12	18204	47	MEF2C,DOCK8,GNAQ,MEF2A,KCNQ3,PTPRJ,HDAC9,ZBTB20,ITPR2,ABCC4,SLC8A1,DOCK4
1.717e-02	-4.06	CSTPP1 (centriolar satellite-associated tubulin polyglutamylase complex regulator 1)	protein interactions	79096	78	2	19454	50	PICALM,ZFHX3
1.718e-02	-4.06	Calcium signaling pathway	KEGG pathways	ko04020	181	3	7161	22	ITPR2,SLC8A1,GNAQ
1.718e-02	-4.06	Calcium signaling pathway	KEGG pathways	hsa04020	181	3	7161	22	GNAQ,SLC8A1,ITPR2
1.721e-02	-4.06	skin-ankle-malignant_melanoma	COSMIC cancer mutations	skin-ankle-malignant_melanoma	69	2	16828	49	PTPRJ,ADAM28
1.724e-02	-4.06	synaptic vesicle	cellular component	GO:0008021	222	3	19108	47	PICALM,DISC1,SYNDIG1
1.726e-02	-4.06	Synthesis of substrates in N-glycan biosythesis	REACTOME pathways	R-HSA-446219	63	2	10285	33	ST6GALNAC3,ST6GAL1
1.730e-02	-4.06	mouth	COSMIC cancer mutations	mouth	9004	34	16828	49	ZBTB20,SFMBT2,SLC8A1,DOCK4,EPB41L2,ITPR2,ELMO1,ARHGAP26,SSH2,ZSWIM6,KCNQ3,QKI,DOCK8,DIP2B,HDAC9,MAML3,MEF2C,MAML2,MED13L,ARHGAP22,ST6GAL1,MAP4K4,SYNDIG1,DSCAM,ZFHX3,ANKRD44,DISC1,ADAM28,SORL1,UBE2E2,FCHSD2,GNAQ,CHST11,NAV3
1.735e-02	-4.05	astroblastoma	COSMIC cancer mutations	astroblastoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-shoulder-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-lentigo_maligna	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-sun_exposed_site-malignant_melanoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-shoulder-benign_melanocytic_nevus	COSMIC cancer mutations	skin-shoulder-benign_melanocytic_nevus	6	1	16828	49	GNAQ
1.735e-02	-4.05	spitzoid	COSMIC cancer mutations	spitzoid	6	1	16828	49	GNAQ
1.735e-02	-4.05	central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_I	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-knee-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-knee-benign_melanocytic_nevus-melanocytic_tumour	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-ear-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-ear-benign_melanocytic_nevus-blue	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-chest-benign_melanocytic_nevus	COSMIC cancer mutations	skin-chest-benign_melanocytic_nevus	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-upper_leg-benign_melanocytic_nevus	COSMIC cancer mutations	skin-upper_leg-benign_melanocytic_nevus	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-upper_arm-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-upper_arm-benign_melanocytic_nevus-blue	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-back-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-back-benign_melanocytic_nevus-melanocytic_tumour	6	1	16828	49	GNAQ
1.735e-02	-4.05	large_intestine-anus-malignant_melanoma	COSMIC cancer mutations	large_intestine-anus-malignant_melanoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	gangliocytoma	COSMIC cancer mutations	gangliocytoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	meninges-melanocytoma	COSMIC cancer mutations	meninges-melanocytoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-arm-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-arm-benign_melanocytic_nevus-melanocytic_tumour	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-upper_back-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-upper_back-benign_melanocytic_nevus-melanocytic_tumour	6	1	16828	49	GNAQ
1.735e-02	-4.05	melanocytoma	COSMIC cancer mutations	melanocytoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-upper_arm-benign_melanocytic_nevus-Spitz	COSMIC cancer mutations	skin-upper_arm-benign_melanocytic_nevus-Spitz	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-eye-malignant_melanoma	COSMIC cancer mutations	skin-eye-malignant_melanoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-lower_leg-benign_melanocytic_nevus	COSMIC cancer mutations	skin-lower_leg-benign_melanocytic_nevus	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-upper_leg-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-upper_leg-benign_melanocytic_nevus-blue	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-scalp-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-scalp-benign_melanocytic_nevus-melanocytic_tumour	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-ankle-malignant_melanoma-nodular	COSMIC cancer mutations	skin-ankle-malignant_melanoma-nodular	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-sun_unexposed_site-malignant_melanoma	COSMIC cancer mutations	skin-sun_unexposed_site-malignant_melanoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-buttock-benign_melanocytic_nevus-blue	COSMIC cancer mutations	skin-buttock-benign_melanocytic_nevus-blue	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-subungual-malignant_melanoma	COSMIC cancer mutations	skin-subungual-malignant_melanoma	6	1	16828	49	GNAQ
1.735e-02	-4.05	skin-upper_arm-benign_melanocytic_nevus	COSMIC cancer mutations	skin-upper_arm-benign_melanocytic_nevus	6	1	16828	49	GNAQ
1.741e-02	-4.05	FN3	prosite domains	PS50853	192	3	12186	35	SORL1,DSCAM,PTPRJ
1.743e-02	-4.05	FN3_sf	interpro domains	IPR036116	203	3	18521	50	SORL1,PTPRJ,DSCAM
1.743e-02	-4.05	FN3_dom	interpro domains	IPR003961	203	3	18521	50	PTPRJ,SORL1,DSCAM
1.743e-02	-4.05	FN3	smart domains	SM00060	149	3	9717	36	PTPRJ,SORL1,DSCAM
1.756e-02	-4.04	negative regulation of transferase activity	biological process	GO:0051348	213	3	18204	47	GNAQ,SLC8A1,PTPRJ
1.766e-02	-4.04	Long-term potentiation	KEGG pathways	hsa04720	67	2	7161	22	ITPR2,GNAQ
1.766e-02	-4.04	Long-term potentiation	KEGG pathways	ko04720	67	2	7161	22	ITPR2,GNAQ
1.777e-02	-4.03	cellular response to inorganic substance	biological process	GO:0071241	214	3	18204	47	MEF2C,MEF2A,KCNQ3
1.778e-02	-4.03	MAP kinase activation in TLR cascade	REACTOME pathways	R-HSA-450294	64	2	10285	33	MEF2C,MEF2A
1.782e-02	-4.03	positive regulation of cell migration	biological process	GO:0030335	592	5	18204	47	DOCK8,MAP4K4,HDAC9,DOCK4,PTPRJ
1.783e-02	-4.03	Endochondral Ossification	WikiPathways	WP474	65	2	5310	17	MEF2C,CHST11
1.786e-02	-4.03	MYT1L (myelin transcription factor 1 like)	protein interactions	23040	7	1	19454	50	DISC1
1.786e-02	-4.03	FGD3 (FYVE, RhoGEF and PH domain containing 3)	protein interactions	89846	7	1	19454	50	ARHGAP22
1.786e-02	-4.03	SOX18 (SRY-box transcription factor 18)	protein interactions	54345	7	1	19454	50	MEF2C
1.786e-02	-4.03	MESP2 (mesoderm posterior bHLH transcription factor 2)	protein interactions	145873	7	1	19454	50	TCF12
1.786e-02	-4.03	OR10S1 (olfactory receptor family 10 subfamily S member 1)	protein interactions	219873	7	1	19454	50	ABCC4
1.786e-02	-4.03	RGS18 (regulator of G protein signaling 18)	protein interactions	64407	7	1	19454	50	GNAQ
1.786e-02	-4.03	ZBTB45 (zinc finger and BTB domain containing 45)	protein interactions	84878	7	1	19454	50	ZBTB20
1.786e-02	-4.03	Pum2 (pumilio RNA-binding family member 2)	protein interactions	80913	7	1	19454	50	QKI
1.786e-02	-4.03	Cfl1 (cofilin 1, non-muscle)	protein interactions	12631	7	1	19454	50	SSH2
1.786e-02	-4.03	ZNF701 (zinc finger protein 701)	protein interactions	55762	7	1	19454	50	ARHGAP24
1.786e-02	-4.03	ZNF501 (zinc finger protein 501)	protein interactions	115560	7	1	19454	50	ARHGAP24
1.793e-02	-4.02	AH/BAR_dom_sf	interpro domains	IPR027267	76	2	18521	50	ARHGAP26,FCHSD2
1.794e-02	-4.02	negative regulation of ruffle assembly	biological process	GO:1900028	7	1	18204	47	ARHGAP24
1.794e-02	-4.02	platelet degranulation	biological process	GO:0002576	7	1	18204	47	ABCC4
1.794e-02	-4.02	relaxation of smooth muscle	biological process	GO:0044557	7	1	18204	47	SLC8A1
1.794e-02	-4.02	leukotriene transport	biological process	GO:0071716	7	1	18204	47	ABCC4
1.794e-02	-4.02	positive regulation of skeletal muscle cell differentiation	biological process	GO:2001016	7	1	18204	47	MEF2C
1.794e-02	-4.02	regulation of 3'-UTR-mediated mRNA stabilization	biological process	GO:1905868	7	1	18204	47	QKI
1.794e-02	-4.02	positive regulation of behavioral fear response	biological process	GO:2000987	7	1	18204	47	MEF2C
1.794e-02	-4.02	glutathione transmembrane transport	biological process	GO:0034775	7	1	18204	47	ABCC4
1.794e-02	-4.02	positive regulation of axon extension involved in axon guidance	biological process	GO:0048842	7	1	18204	47	DSCAM
1.794e-02	-4.02	response to gonadotropin-releasing hormone	biological process	GO:0097210	7	1	18204	47	TCF12
1.794e-02	-4.02	amyloid-beta clearance by transcytosis	biological process	GO:0150093	7	1	18204	47	PICALM
1.801e-02	-4.02	MED13 (mediator complex subunit 13)	protein interactions	9969	80	2	19454	50	MED13L,QKI
1.806e-02	-4.01	TYR_PHOSPHATASE_1	prosite domains	PS00383	72	2	12186	35	PTPRJ,SSH2
1.811e-02	-4.01	IP3 receptor type 1 binding core, RIH domain	gene3d domains	1.25.10.30	6	1	14470	44	ITPR2
1.815e-02	-4.01	Bile Acid Direct Signalling Pathway (1)	SMPDB pathways	SMP0086608	5	1	1369	5	ABCC4
1.816e-02	-4.01	frontal_lobe	COSMIC cancer mutations	frontal_lobe	71	2	16828	49	GNAQ,ZFHX3
1.824e-02	-4.00	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma	6953	28	16828	49	SFMBT2,SLC8A1,EPB41L2,DOCK4,ZBTB20,SSH2,ITPR2,ELMO1,DIP2B,HDAC9,MAML3,KCNQ3,QKI,MAML2,MED13L,MEF2C,ST6GAL1,MAP4K4,ANKRD44,DSCAM,ZFHX3,GNAQ,ADAM28,DISC1,SORL1,UBE2E2,FCHSD2,NAV3
1.828e-02	-4.00	protein-macromolecule adaptor activity	molecular function	GO:0030674	989	7	18094	50	MAML3,MAML2,FRMD4A,MED13L,SFMBT2,QKI,HDAC9
1.831e-02	-4.00	O-linked glycosylation of mucins	REACTOME pathways	R-HSA-913709	65	2	10285	33	ST6GALNAC3,ST6GAL1
1.839e-02	-4.00	VPS10	smart domains	SM00602	5	1	9717	36	SORL1
1.843e-02	-3.99	CUEDC1 (CUE domain containing 1)	protein interactions	404093	81	2	19454	50	UBE2E2,LDLRAD4
1.857e-02	-3.99	regulation of amide metabolic process	biological process	GO:0034248	81	2	18204	47	SORL1,PICALM
1.865e-02	-3.98	leukocyte activation	biological process	GO:0045321	599	5	18204	47	DOCK8,MEF2C,HDAC9,APBB1IP,PTPRJ
1.875e-02	-3.98	Carb_sulfotrans_8-10	interpro domains	IPR018011	7	1	18521	50	CHST11
1.875e-02	-3.98	Znf_A20	interpro domains	IPR002653	7	1	18521	50	ZFAND3
1.881e-02	-3.97	pharynx	COSMIC cancer mutations	pharynx	2696	14	16828	49	SLC8A1,SFMBT2,DOCK4,ZFHX3,DSCAM,ARHGAP26,ZSWIM6,QKI,DOCK8,GNAQ,DIP2B,HDAC9,MEF2C,MED13L
1.881e-02	-3.97	HDAC4 (histone deacetylase 4)	protein interactions	9759	397	4	19454	50	FCHSD2,HDAC9,MEF2A,MEF2C
1.885e-02	-3.97	negative regulation of cell motility	biological process	GO:2000146	396	4	18204	47	LDLRAD4,MEF2C,NAV3,PTPRJ
1.886e-02	-3.97	MED30 (mediator complex subunit 30)	protein interactions	90390	82	2	19454	50	MED13L,DOCK8
1.886e-02	-3.97	MEF2D (myocyte enhancer factor 2D)	protein interactions	4209	82	2	19454	50	MEF2A,MEF2C
1.897e-02	-3.97	NOP2 (NOP2 nucleolar protein)	protein interactions	4839	398	4	19454	50	HDAC9,PTPRJ,MAP4K4,ARHGAP24
1.897e-02	-3.96	human chr9q21.2	chromosome location	human chr9q21.2	10	1	26134	50	GNAQ
1.897e-02	-3.96	human chr12p11.23	chromosome location	human chr12p11.23	10	1	26134	50	ITPR2
1.901e-02	-3.96	regulation of bone mineralization	biological process	GO:0030500	82	2	18204	47	MEF2C,SLC8A1
1.911e-02	-3.96	chondroblastoma	COSMIC cancer mutations	chondroblastoma	534	5	16828	49	ST6GALNAC3,ARHGAP26,ZFAND3,SLC9A9,DSCAM
1.912e-02	-3.96	zf-A20	pfam domains	PF01754	7	1	17795	49	ZFAND3
1.913e-02	-3.96	regulation of growth	biological process	GO:0040008	603	5	18204	47	DSCAM,PTPRJ,DIP2B,MEF2C,DISC1
1.914e-02	-3.96	lung-left_lower_lobe-carcinoma-adenocarcinoma	COSMIC cancer mutations	lung-left_lower_lobe-carcinoma-adenocarcinoma	73	2	16828	49	HDAC9,NAV3
1.916e-02	-3.95	developmental process	biological process	GO:0032502	5716	22	18204	47	ZFHX3,MAP4K4,CHST11,MEF2C,ADAM28,SLC8A1,PICALM,ARHGAP22,TCF12,ARHGAP26,DIP2B,HDAC9,NAV3,DSCAM,KCNQ3,ARHGAP24,QKI,DISC1,ZSWIM6,PTPRJ,MEF2A,SSH2
1.919e-02	-3.95	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	molecular function	GO:0008467	7	1	18094	50	HS3ST4
1.919e-02	-3.95	phosphotransferase activity, nitrogenous group as acceptor	molecular function	GO:0016775	7	1	18094	50	MAP4K4
1.919e-02	-3.95	tripeptide transmembrane transporter activity	molecular function	GO:0042937	7	1	18094	50	ABCC4
1.930e-02	-3.95	GGA2 (golgi associated, gamma adaptin ear containing, ARF binding protein 2)	protein interactions	23062	83	2	19454	50	PICALM,SORL1
1.930e-02	-3.95	NEXN (nexilin F-actin binding protein)	protein interactions	91624	83	2	19454	50	ARHGAP24,DISC1
1.951e-02	-3.94	presynaptic endocytic zone membrane	cellular component	GO:0098835	8	1	19108	47	PICALM
1.954e-02	-3.94	SH3-like_dom_sf	interpro domains	IPR036028	212	3	18521	50	DOCK4,ARHGAP26,FCHSD2
1.957e-02	-3.93	MAPK cascade	biological process	GO:0000165	222	3	18204	47	MEF2C,MAP4K4,MEF2A
1.958e-02	-3.93	skin-shoulder-malignant_melanoma	COSMIC cancer mutations	skin-shoulder-malignant_melanoma	355	4	16828	49	GNAQ,PTPRJ,FRMD4A,ADAM28
1.962e-02	-3.93	skin-nipple-malignant_melanoma	COSMIC cancer mutations	skin-nipple-malignant_melanoma	197	3	16828	49	DSCAM,DISC1,SORL1
1.962e-02	-3.93	nipple	COSMIC cancer mutations	nipple	197	3	16828	49	DISC1,SORL1,DSCAM
1.964e-02	-3.93	regulation of cell growth	biological process	GO:0001558	401	4	18204	47	DSCAM,DIP2B,PTPRJ,DISC1
1.972e-02	-3.93	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia	739	6	16828	49	ZSWIM6,TBC1D22A,SLC8A1,SFMBT2,DSCAM,ZFHX3
1.972e-02	-3.93	acute_lymphoblastic_T_cell_leukaemia	COSMIC cancer mutations	acute_lymphoblastic_T_cell_leukaemia	739	6	16828	49	ZSWIM6,TBC1D22A,SLC8A1,SFMBT2,ZFHX3,DSCAM
1.974e-02	-3.93	SERF2 (small EDRK-rich factor 2)	protein interactions	10169	84	2	19454	50	QKI,NAV3
1.977e-02	-3.92	chondrosarcoma	COSMIC cancer mutations	chondrosarcoma	1181	8	16828	49	NAV3,CHST11,ZFHX3,HS3ST4,TCF12,DOCK4,SYNDIG1,MAML3
1.985e-02	-3.92	MAPRE3 (microtubule associated protein RP/EB family member 3)	protein interactions	22924	224	3	19454	50	DOCK4,MAP4K4,DIP2B
1.989e-02	-3.92	proteoglycan metabolic process	biological process	GO:0006029	84	2	18204	47	CHST11,HS3ST4
1.994e-02	-3.92	ZF_A20	prosite domains	PS51036	7	1	12186	35	ZFAND3
2.021e-02	-3.90	skin-arm-benign_melanocytic_nevus	COSMIC cancer mutations	skin-arm-benign_melanocytic_nevus	7	1	16828	49	GNAQ
2.021e-02	-3.90	skin-lower_back-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-lower_back-benign_melanocytic_nevus-congenital	7	1	16828	49	GNAQ
2.021e-02	-3.90	blue	COSMIC cancer mutations	blue	7	1	16828	49	GNAQ
2.021e-02	-3.90	central_nervous_system-temporal_lobe-other-ganglioglioma	COSMIC cancer mutations	central_nervous_system-temporal_lobe-other-ganglioglioma	7	1	16828	49	GNAQ
2.021e-02	-3.90	skin-benign_melanocytic_nevus-intradermal	COSMIC cancer mutations	skin-benign_melanocytic_nevus-intradermal	7	1	16828	49	GNAQ
2.021e-02	-3.90	sun_unexposed_site	COSMIC cancer mutations	sun_unexposed_site	7	1	16828	49	GNAQ
2.027e-02	-3.90	striated muscle cell differentiation	biological process	GO:0051146	225	3	18204	47	MEF2C,MEF2A,SLC8A1
2.033e-02	-3.90	chondrocyte differentiation	biological process	GO:0002062	85	2	18204	47	CHST11,MEF2C
2.038e-02	-3.89	KMO (kynurenine 3-monooxygenase)	protein interactions	8564	8	1	19454	50	DISC1
2.038e-02	-3.89	GRM4 (glutamate metabotropic receptor 4)	protein interactions	2914	8	1	19454	50	GNAQ
2.038e-02	-3.89	Id2 (inhibitor of DNA binding 2)	protein interactions	15902	8	1	19454	50	TCF12
2.038e-02	-3.89	ZNF568 (zinc finger protein 568)	protein interactions	374900	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	SH3BGR (SH3 domain binding glutamate rich protein)	protein interactions	6450	8	1	19454	50	FCHSD2
2.038e-02	-3.89	ZNF236 (zinc finger protein 236)	protein interactions	7776	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	Tamalin (trafficking regulator and scaffold protein tamalin)	protein interactions	192254	8	1	19454	50	FCHSD2
2.038e-02	-3.89	ZNF28 (zinc finger protein 28)	protein interactions	7576	8	1	19454	50	ARHGAP24
2.038e-02	-3.89	DEPP1 (DEPP autophagy regulator 1)	protein interactions	11067	8	1	19454	50	QKI
2.047e-02	-3.89	regulation of germinal center formation	biological process	GO:0002634	8	1	18204	47	MEF2C
2.047e-02	-3.89	membrane hyperpolarization	biological process	GO:0060081	8	1	18204	47	KCNQ3
2.047e-02	-3.89	negative regulation of macrophage apoptotic process	biological process	GO:2000110	8	1	18204	47	ST6GAL1
2.047e-02	-3.89	cardiac ventricle formation	biological process	GO:0003211	8	1	18204	47	MEF2C
2.047e-02	-3.89	contact inhibition	biological process	GO:0060242	8	1	18204	47	PTPRJ
2.047e-02	-3.89	positive regulation of Arp2/3 complex-mediated actin nucleation	biological process	GO:2000601	8	1	18204	47	FCHSD2
2.047e-02	-3.89	positive regulation of fear response	biological process	GO:1903367	8	1	18204	47	MEF2C
2.047e-02	-3.89	positive regulation of endocytic recycling	biological process	GO:2001137	8	1	18204	47	SORL1
2.055e-02	-3.88	MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4)	protein interactions	9448	227	3	19454	50	DISC1,MAP4K4,DSCAM
2.063e-02	-3.88	H2AC18 (H2A clustered histone 18)	protein interactions	8337	86	2	19454	50	PICALM,MAP4K4
2.071e-02	-3.88	postsynapse	cellular component	GO:0098794	646	5	19108	47	DISC1,SLC8A1,PICALM,MEF2C,SYNDIG1
2.073e-02	-3.88	stomach	COSMIC cancer mutations	stomach	15550	49	16828	49	MAML2,MEF2C,DIP2B,MAML3,DOCK8,TBC1D22A,ITPR2,FRMD4A,SLC9A9,HS3ST4,NAV3,ADAM28,APBB1IP,ST6GALNAC3,ZFHX3,PICALM,SYNDIG1,TCF12,MED13L,HDAC9,KCNQ3,QKI,SSH2,ZSWIM6,MEF2A,ELMO1,ARHGAP26,SFMBT2,SLC8A1,EPB41L2,DOCK4,ZBTB20,ZFAND3,CHST11,GNAQ,SORL1,DISC1,UBE2E2,FCHSD2,ABCC4,PTPRJ,ANKRD44,PLXDC2,DSCAM,ATP8B4,ARHGAP22,ARHGAP24,ST6GAL1,MAP4K4
2.082e-02	-3.87	humerus	COSMIC cancer mutations	humerus	546	5	16828	49	DOCK4,ST6GALNAC3,ARHGAP26,DSCAM,ZFHX3
2.108e-02	-3.86	CDK19 (cyclin dependent kinase 19)	protein interactions	23097	87	2	19454	50	GNAQ,MED13L
2.108e-02	-3.86	PAPOLA (poly(A) polymerase alpha)	protein interactions	10914	87	2	19454	50	ARHGAP24,PICALM
2.110e-02	-3.86	-	gene3d domains	1.20.5.4770	7	1	14470	44	ZFAND3
2.111e-02	-3.86	specific granule membrane	cellular component	GO:0035579	91	2	19108	47	ATP8B4,PTPRJ
2.117e-02	-3.86	positive regulation of cell motility	biological process	GO:2000147	619	5	18204	47	DOCK8,MAP4K4,HDAC9,DOCK4,PTPRJ
2.121e-02	-3.85	axon	cellular component	GO:0030424	650	5	19108	47	KCNQ3,DIP2B,DSCAM,SLC8A1,DISC1
2.127e-02	-3.85	BICD1 (BICD cargo adaptor 1)	protein interactions	636	230	3	19454	50	DSCAM,DISC1,DOCK4
2.129e-02	-3.85	Thyroid hormone synthesis	KEGG pathways	ko04918	74	2	7161	22	ITPR2,GNAQ
2.129e-02	-3.85	Thyroid hormone synthesis	KEGG pathways	hsa04918	74	2	7161	22	GNAQ,ITPR2
2.138e-02	-3.85	exocytic vesicle	cellular component	GO:0070382	241	3	19108	47	SYNDIG1,DISC1,PICALM
2.140e-02	-3.84	AN1-like_Znf	interpro domains	IPR035896	8	1	18521	50	ZFAND3
2.140e-02	-3.84	Znf_AN1	interpro domains	IPR000058	8	1	18521	50	ZFAND3
2.159e-02	-3.84	TRIM37 (tripartite motif containing 37)	protein interactions	4591	624	5	19454	50	DSCAM,ARHGAP22,UBE2E2,DISC1,TCF12
2.159e-02	-3.84	CSK (C-terminal Src kinase)	protein interactions	1445	854	6	19454	50	DISC1,FCHSD2,SLC8A1,ADAM28,ARHGAP26,ELMO1
2.167e-02	-3.83	left_lower_lobe	COSMIC cancer mutations	left_lower_lobe	78	2	16828	49	NAV3,HDAC9
2.182e-02	-3.82	zf-AN1	pfam domains	PF01428	8	1	17795	49	ZFAND3
2.184e-02	-3.82	Gastric acid secretion	KEGG pathways	ko04971	75	2	7161	22	ITPR2,GNAQ
2.184e-02	-3.82	Gastric acid secretion	KEGG pathways	hsa04971	75	2	7161	22	ITPR2,GNAQ
2.190e-02	-3.82	aspartic-type endopeptidase inhibitor activity	molecular function	GO:0019828	8	1	18094	50	SORL1
2.190e-02	-3.82	ABC-type glutathione S-conjugate transporter activity	molecular function	GO:0015431	8	1	18094	50	ABCC4
2.190e-02	-3.82	PH domain binding	molecular function	GO:0042731	8	1	18094	50	EPB41L2
2.193e-02	-3.82	spectrin	cellular component	GO:0008091	9	1	19108	47	EPB41L2
2.193e-02	-3.82	platelet dense tubular network membrane	cellular component	GO:0031095	9	1	19108	47	ITPR2
2.193e-02	-3.82	presynaptic endocytic zone	cellular component	GO:0098833	9	1	19108	47	PICALM
2.194e-02	-3.82	cell motility	biological process	GO:0048870	1101	7	18204	47	DOCK8,SORL1,DISC1,MEF2C,ARHGAP24,DOCK4,ELMO1
2.203e-02	-3.82	DMAP_binding	smart domains	SM01137	6	1	9717	36	DIP2B
2.203e-02	-3.82	SH3_domain	interpro domains	IPR001452	222	3	18521	50	ARHGAP26,FCHSD2,DOCK4
2.212e-02	-3.81	RHOJ (ras homolog family member J)	protein interactions	57381	628	5	19454	50	DIP2B,MAP4K4,PICALM,DOCK8,PTPRJ
2.216e-02	-3.81	post-embryonic development	biological process	GO:0009791	89	2	18204	47	DSCAM,CHST11
2.220e-02	-3.81	transport vesicle	cellular component	GO:0030133	437	4	19108	47	SYNDIG1,DISC1,SORL1,PICALM
2.234e-02	-3.80	Arfaptin homology (AH) domain/BAR domain	gene3d domains	1.20.1270.60	76	2	14470	44	FCHSD2,ARHGAP26
2.243e-02	-3.80	follicular_lymphoma	COSMIC cancer mutations	follicular_lymphoma	1209	8	16828	49	PLXDC2,ST6GALNAC3,DSCAM,ITPR2,SLC8A1,GNAQ,SLC9A9,UBE2E2
2.246e-02	-3.80	CDKN2C (cyclin dependent kinase inhibitor 2C)	protein interactions	1031	90	2	19454	50	ANKRD44,TCF12
2.260e-02	-3.79	Tyr_Pase_dom	interpro domains	IPR000387	86	2	18521	50	SSH2,PTPRJ
2.266e-02	-3.79	regulation of protein-containing complex assembly	biological process	GO:0043254	419	4	18204	47	NAV3,FCHSD2,SSH2,SORL1
2.272e-02	-3.78	human chr6q26	chromosome location	human chr6q26	12	1	26134	50	QKI
2.275e-02	-3.78	ZF_AN1	prosite domains	PS51039	8	1	12186	35	ZFAND3
2.290e-02	-3.78	SEMA3A (semaphorin 3A)	protein interactions	10371	9	1	19454	50	DISC1
2.290e-02	-3.78	SCRT1 (scratch family transcriptional repressor 1)	protein interactions	83482	9	1	19454	50	SORL1
2.290e-02	-3.78	ZNF766 (zinc finger protein 766)	protein interactions	90321	9	1	19454	50	ARHGAP24
2.290e-02	-3.78	CHKA (choline kinase alpha)	protein interactions	1119	9	1	19454	50	FCHSD2
2.290e-02	-3.78	PPFIA4 (PTPRF interacting protein alpha 4)	protein interactions	8497	9	1	19454	50	DISC1
2.290e-02	-3.78	Ywhag (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)	protein interactions	22628	9	1	19454	50	QKI
2.290e-02	-3.78	AKR1D1 (aldo-keto reductase family 1 member D1)	protein interactions	6718	9	1	19454	50	PLXDC2
2.290e-02	-3.78	PSD (pleckstrin and Sec7 domain containing)	protein interactions	5662	9	1	19454	50	GNAQ
2.290e-02	-3.78	LRTM2 (leucine rich repeats and transmembrane domains 2)	protein interactions	654429	9	1	19454	50	ABCC4
2.290e-02	-3.78	KLB (klotho beta)	protein interactions	152831	9	1	19454	50	ARHGAP24
2.290e-02	-3.78	CUX2 (cut like homeobox 2)	protein interactions	23316	9	1	19454	50	NAV3
2.290e-02	-3.78	GBP3 (guanylate binding protein 3)	protein interactions	2635	9	1	19454	50	MAP4K4
2.290e-02	-3.78	OPHN1 (oligophrenin 1)	protein interactions	4983	9	1	19454	50	ARHGAP26
2.290e-02	-3.78	PCNX4 (pecanex 4)	protein interactions	64430	9	1	19454	50	DISC1
2.290e-02	-3.78	CFAP91 (cilia and flagella associated protein 91)	protein interactions	89876	9	1	19454	50	DSCAM
2.292e-02	-3.78	DAD1 (defender against cell death 1)	protein interactions	1603	91	2	19454	50	LDLRAD4,PICALM
2.292e-02	-3.78	TRIO (trio Rho guanine nucleotide exchange factor)	protein interactions	7204	91	2	19454	50	NAV3,DISC1
2.295e-02	-3.77	Signaling events mediated by focal adhesion kinase	Pathway Interaction DB	fak_pathway	54	2	2226	10	ELMO1,ARHGAP26
2.300e-02	-3.77	phospholipase C-activating dopamine receptor signaling pathway	biological process	GO:0060158	9	1	18204	47	GNAQ
2.300e-02	-3.77	detection of cell density	biological process	GO:0060245	9	1	18204	47	PTPRJ
2.300e-02	-3.77	positive regulation of myeloid cell apoptotic process	biological process	GO:0033034	9	1	18204	47	MEF2C
2.300e-02	-3.77	positive regulation of protein localization to early endosome	biological process	GO:1902966	9	1	18204	47	SORL1
2.300e-02	-3.77	tripeptide transmembrane transport	biological process	GO:0035443	9	1	18204	47	ABCC4
2.300e-02	-3.77	regulation of protein localization to cell cortex	biological process	GO:1904776	9	1	18204	47	EPB41L2
2.300e-02	-3.77	regulation of protein localization to early endosome	biological process	GO:1902965	9	1	18204	47	SORL1
2.300e-02	-3.77	glomerulus morphogenesis	biological process	GO:0072102	9	1	18204	47	MEF2C
2.300e-02	-3.77	glutathione transport	biological process	GO:0034635	9	1	18204	47	ABCC4
2.300e-02	-3.77	netrin-activated signaling pathway	biological process	GO:0038007	9	1	18204	47	DSCAM
2.300e-02	-3.77	regulation of vascular associated smooth muscle contraction	biological process	GO:0003056	9	1	18204	47	DOCK4
2.306e-02	-3.77	skin-vulva-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-vulva-malignant_melanoma-superficial_spreading	8	1	16828	49	GNAQ
2.306e-02	-3.77	skin-mucosal-malignant_melanoma-desmoplastic	COSMIC cancer mutations	skin-mucosal-malignant_melanoma-desmoplastic	8	1	16828	49	GNAQ
2.306e-02	-3.77	melanocytic_neoplasm	COSMIC cancer mutations	melanocytic_neoplasm	8	1	16828	49	GNAQ
2.306e-02	-3.77	eye-malignant_melanoma	COSMIC cancer mutations	eye-malignant_melanoma	8	1	16828	49	GNAQ
2.306e-02	-3.77	meninges-malignant_melanoma	COSMIC cancer mutations	meninges-malignant_melanoma	8	1	16828	49	GNAQ
2.306e-02	-3.77	skin-vulva-malignant_melanoma-nodular	COSMIC cancer mutations	skin-vulva-malignant_melanoma-nodular	8	1	16828	49	GNAQ
2.306e-02	-3.77	skin-vulva-malignant_melanoma-mucosal_lentiginous	COSMIC cancer mutations	skin-vulva-malignant_melanoma-mucosal_lentiginous	8	1	16828	49	GNAQ
2.306e-02	-3.77	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-chiasm-glioma-astrocytoma_Grade_I	8	1	16828	49	QKI
2.306e-02	-3.77	skin-chronically_sun_exposed_site-malignant_melanoma	COSMIC cancer mutations	skin-chronically_sun_exposed_site-malignant_melanoma	8	1	16828	49	GNAQ
2.306e-02	-3.77	meninges-melanocytic_neoplasm	COSMIC cancer mutations	meninges-melanocytic_neoplasm	8	1	16828	49	GNAQ
2.306e-02	-3.77	skin-acral-malignant_melanoma-acral_lentiginous	COSMIC cancer mutations	skin-acral-malignant_melanoma-acral_lentiginous	8	1	16828	49	GNAQ
2.306e-02	-3.77	skin-mucosal-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-mucosal-malignant_melanoma-superficial_spreading	8	1	16828	49	GNAQ
2.306e-02	-3.77	chronically_sun_exposed_site	COSMIC cancer mutations	chronically_sun_exposed_site	8	1	16828	49	GNAQ
2.309e-02	-3.77	positive regulation of protein polymerization	biological process	GO:0032273	91	2	18204	47	FCHSD2,NAV3
2.313e-02	-3.77	chondroitin sulfate biosynthesis (late stages)	BIOCYC pathways	META_PWY-6567	7	1	902	3	CHST11
2.325e-02	-3.76	forearm	COSMIC cancer mutations	forearm	81	2	16828	49	GNAQ,PTPRJ
2.332e-02	-3.76	sarcoplasm	cellular component	GO:0016528	96	2	19108	47	MEF2C,ITPR2
2.335e-02	-3.76	Oncogenic MAPK signaling	REACTOME pathways	R-HSA-6802957	74	2	10285	33	APBB1IP,QKI
2.338e-02	-3.76	PRNP (prion protein (Kanno blood group))	protein interactions	5621	1118	7	19454	50	PICALM,SSH2,MAML2,QKI,MEF2C,EPB41L2,DOCK4
2.339e-02	-3.76	CAMK1 (calcium/calmodulin dependent protein kinase I)	protein interactions	8536	92	2	19454	50	HDAC9,ST6GALNAC3
2.357e-02	-3.75	positive regulation of mononuclear cell migration	biological process	GO:0071677	92	2	18204	47	DOCK8,PTPRJ
2.375e-02	-3.74	bone-osteosarcoma	COSMIC cancer mutations	bone-osteosarcoma	212	3	16828	49	ELMO1,ARHGAP26,SFMBT2
2.387e-02	-3.74	FAM76B (family with sequence similarity 76 member B)	protein interactions	143684	93	2	19454	50	EPB41L2,SORL1
2.404e-02	-3.73	NaCa_Exmemb	interpro domains	IPR004837	9	1	18521	50	SLC8A1
2.404e-02	-3.73	NCX_ion-bd_dom_sf	interpro domains	IPR044880	9	1	18521	50	SLC8A1
2.404e-02	-3.73	Mbt	interpro domains	IPR004092	9	1	18521	50	SFMBT2
2.404e-02	-3.73	CalX-like_sf	interpro domains	IPR038081	9	1	18521	50	SLC8A1
2.404e-02	-3.73	Znf_SWIM	interpro domains	IPR007527	9	1	18521	50	ZSWIM6
2.404e-02	-3.73	Calx_beta	interpro domains	IPR003644	9	1	18521	50	SLC8A1
2.404e-02	-3.73	NaH_exchanger	interpro domains	IPR004709	9	1	18521	50	SLC9A9
2.405e-02	-3.73	osteosarcoma	COSMIC cancer mutations	osteosarcoma	213	3	16828	49	SFMBT2,ARHGAP26,ELMO1
2.405e-02	-3.73	positive regulation of cellular component organization	biological process	GO:0051130	1122	7	18204	47	NAV3,SYNDIG1,PTPRJ,MAP4K4,FCHSD2,DISC1,DSCAM
2.407e-02	-3.73	AN1-like Zinc finger	gene3d domains	4.10.1110.10	8	1	14470	44	ZFAND3
2.411e-02	-3.72	TYR_PHOSPHATASE_2	prosite domains	PS50056	84	2	12186	35	SSH2,PTPRJ
2.417e-02	-3.72	positive regulation of developmental process	biological process	GO:0051094	1385	8	18204	47	MEF2C,SYNDIG1,QKI,DISC1,TCF12,SORL1,SLC8A1,DSCAM
2.427e-02	-3.72	intracellular monoatomic cation homeostasis	biological process	GO:0030003	428	4	18204	47	DISC1,SLC9A9,SLC8A1,PICALM
2.433e-02	-3.72	Golgi trans cisterna	cellular component	GO:0000138	10	1	19108	47	ST6GAL1
2.435e-02	-3.72	TRAF3IP1 (TRAF3 interacting protein 1)	protein interactions	26146	94	2	19454	50	DISC1,FRMD4A
2.452e-02	-3.71	Calx-beta	pfam domains	PF03160	9	1	17795	49	SLC8A1
2.452e-02	-3.71	Na_Ca_ex	pfam domains	PF01699	9	1	17795	49	SLC8A1
2.452e-02	-3.71	MBT	pfam domains	PF02820	9	1	17795	49	SFMBT2
2.452e-02	-3.71	PH_12	pfam domains	PF16457	9	1	17795	49	ELMO1
2.453e-02	-3.71	positive regulation of neuron differentiation	biological process	GO:0045666	94	2	18204	47	MEF2C,TCF12
2.453e-02	-3.71	negative regulation of protein serine/threonine kinase activity	biological process	GO:0071901	94	2	18204	47	SLC8A1,PTPRJ
2.460e-02	-3.70	ATPase-coupled lipid transmembrane transporter activity	molecular function	GO:0034040	9	1	18094	50	ABCC4
2.460e-02	-3.70	urate transmembrane transporter activity	molecular function	GO:0015143	9	1	18094	50	ABCC4
2.460e-02	-3.70	delta-catenin binding	molecular function	GO:0070097	9	1	18094	50	PTPRJ
2.479e-02	-3.70	RBPJ (recombination signal binding protein for immunoglobulin kappa J region)	protein interactions	3516	244	3	19454	50	SFMBT2,MAML3,MAML2
2.483e-02	-3.70	DDX3Y (DEAD-box helicase 3 Y-linked)	protein interactions	8653	95	2	19454	50	ARHGAP24,PICALM
2.483e-02	-3.70	RNF111 (ring finger protein 111)	protein interactions	54778	95	2	19454	50	UBE2E2,GNAQ
2.483e-02	-3.70	CKS1B (CDC28 protein kinase regulatory subunit 1B)	protein interactions	1163	95	2	19454	50	TCF12,GNAQ
2.483e-02	-3.70	LIMK1 (LIM domain kinase 1)	protein interactions	3984	95	2	19454	50	SSH2,DSCAM
2.494e-02	-3.69	regulation of developmental process	biological process	GO:0050793	2540	12	18204	47	HDAC9,QKI,DIP2B,SYNDIG1,MEF2C,DSCAM,SLC8A1,LDLRAD4,TCF12,SORL1,DISC1,ZFHX3
2.502e-02	-3.69	calcium ion transmembrane import into cytosol	biological process	GO:0097553	95	2	18204	47	ITPR2,SLC8A1
2.507e-02	-3.69	guanyl-nucleotide exchange factor activity	molecular function	GO:0005085	228	3	18094	50	DOCK4,ELMO1,DOCK8
2.515e-02	-3.68	amyloid-beta binding	molecular function	GO:0001540	89	2	18094	50	PICALM,SORL1
2.516e-02	-3.68	extrinsic component of plasma membrane	cellular component	GO:0019897	100	2	19108	47	GNAQ,PICALM
2.531e-02	-3.68	BCAS2 (BCAS2 pre-mRNA processing factor)	protein interactions	10286	246	3	19454	50	QKI,DISC1,EPB41L2
2.532e-02	-3.68	RPS6KA4 (ribosomal protein S6 kinase A4)	protein interactions	8986	96	2	19454	50	PTPRJ,PICALM
2.532e-02	-3.68	GNG12 (G protein subunit gamma 12)	protein interactions	55970	96	2	19454	50	MEF2A,GNAQ
2.532e-02	-3.68	MED16 (mediator complex subunit 16)	protein interactions	10025	96	2	19454	50	QKI,MED13L
2.534e-02	-3.68	Sulfite Oxidase Deficiency	SMPDB pathways	SMP0000532	7	1	1369	5	CHST11
2.534e-02	-3.68	G-Protein Signaling Through Tubby Proteins	SMPDB pathways	SMP0089843	7	1	1369	5	GNAQ
2.534e-02	-3.68	Sulfate/Sulfite Metabolism	SMPDB pathways	SMP0000041	7	1	1369	5	CHST11
2.539e-02	-3.67	Rap1 signaling pathway	KEGG pathways	ko04015	210	3	7161	22	APBB1IP,GNAQ,DOCK4
2.539e-02	-3.67	Rap1 signaling pathway	KEGG pathways	hsa04015	210	3	7161	22	APBB1IP,GNAQ,DOCK4
2.539e-02	-3.67	Free fatty acids regulate insulin secretion	REACTOME pathways	R-HSA-400451	8	1	10285	33	GNAQ
2.539e-02	-3.67	Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	REACTOME pathways	R-HSA-434316	8	1	10285	33	GNAQ
2.539e-02	-3.67	Nef and signal transduction	REACTOME pathways	R-HSA-164944	8	1	10285	33	ELMO1
2.541e-02	-3.67	CCDC15 (coiled-coil domain containing 15)	protein interactions	80071	10	1	19454	50	MEF2A
2.541e-02	-3.67	ZNF852 (zinc finger protein 852)	protein interactions	285346	10	1	19454	50	ARHGAP24
2.541e-02	-3.67	TUL1 (ubiquitin-protein ligase TUL1)	protein interactions	853832	10	1	19454	50	UBE2E2
2.541e-02	-3.67	ZNF563 (zinc finger protein 563)	protein interactions	147837	10	1	19454	50	SORL1
2.541e-02	-3.67	Mrpl13 (mitochondrial ribosomal protein L13)	protein interactions	68537	10	1	19454	50	QKI
2.541e-02	-3.67	BANK1 (B cell scaffold protein with ankyrin repeats 1)	protein interactions	55024	10	1	19454	50	ITPR2
2.541e-02	-3.67	METTL26 (methyltransferase like 26)	protein interactions	84326	10	1	19454	50	DISC1
2.541e-02	-3.67	TBPL2 (TATA-box binding protein like 2)	protein interactions	387332	10	1	19454	50	MAP4K4
2.541e-02	-3.67	PRTG (protogenin)	protein interactions	283659	10	1	19454	50	DISC1
2.541e-02	-3.67	Arhgef2 (Rho/Rac guanine nucleotide exchange factor 2)	protein interactions	16800	10	1	19454	50	SORL1
2.541e-02	-3.67	Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1)	protein interactions	15519	10	1	19454	50	QKI
2.541e-02	-3.67	ZNF606 (zinc finger protein 606)	protein interactions	80095	10	1	19454	50	ARHGAP24
2.544e-02	-3.67	SH3	prosite domains	PS50002	222	3	12186	35	ARHGAP26,DOCK4,FCHSD2
2.553e-02	-3.67	regulation of behavioral fear response	biological process	GO:2000822	10	1	18204	47	MEF2C
2.553e-02	-3.67	regulation of peptidyl-lysine acetylation	biological process	GO:2000756	10	1	18204	47	DIP2B
2.553e-02	-3.67	guanine nucleotide transmembrane transport	biological process	GO:1903790	10	1	18204	47	ABCC4
2.553e-02	-3.67	positive regulation of adipose tissue development	biological process	GO:1904179	10	1	18204	47	SORL1
2.553e-02	-3.67	synaptic vesicle budding from presynaptic endocytic zone membrane	biological process	GO:0016185	10	1	18204	47	PICALM
2.553e-02	-3.67	regulation of Fc receptor mediated stimulatory signaling pathway	biological process	GO:0060368	10	1	18204	47	PTPRJ
2.553e-02	-3.67	ventricular cardiac muscle cell development	biological process	GO:0055015	10	1	18204	47	MEF2A
2.553e-02	-3.67	cellular response to parathyroid hormone stimulus	biological process	GO:0071374	10	1	18204	47	MEF2C
2.553e-02	-3.67	germinal center formation	biological process	GO:0002467	10	1	18204	47	MEF2C
2.553e-02	-3.67	sialylation	biological process	GO:0097503	10	1	18204	47	ST6GAL1
2.553e-02	-3.67	embryonic viscerocranium morphogenesis	biological process	GO:0048703	10	1	18204	47	CHST11
2.553e-02	-3.67	regulation of ER to Golgi vesicle-mediated transport	biological process	GO:0060628	10	1	18204	47	SORL1
2.555e-02	-3.67	positive regulation of neurogenesis	biological process	GO:0050769	246	3	18204	47	DISC1,QKI,DSCAM
2.556e-02	-3.67	ZF_SWIM	prosite domains	PS50966	9	1	12186	35	ZSWIM6
2.556e-02	-3.67	ENTH	prosite domains	PS50942	9	1	12186	35	PICALM
2.556e-02	-3.67	MBT	prosite domains	PS51079	9	1	12186	35	SFMBT2
2.557e-02	-3.67	blood vessel morphogenesis	biological process	GO:0048514	435	4	18204	47	PTPRJ,ARHGAP22,ARHGAP24,QKI
2.566e-02	-3.66	ZnF_A20	smart domains	SM00259	7	1	9717	36	ZFAND3
2.566e-02	-3.66	adrenal_cortical_carcinoma	COSMIC cancer mutations	adrenal_cortical_carcinoma	2256	12	16828	49	PTPRJ,ABCC4,ELMO1,MEF2A,ATP8B4,FRMD4A,DOCK4,ST6GAL1,ZBTB20,MAML2,HDAC9,DOCK8
2.576e-02	-3.66	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	REACTOME pathways	R-HSA-446193	78	2	10285	33	ST6GALNAC3,ST6GAL1
2.579e-02	-3.66	response to endogenous stimulus	biological process	GO:0009719	1402	8	18204	47	TCF12,ZFHX3,ITPR2,SLC8A1,GNAQ,MEF2C,HDAC9,CHST11
2.580e-02	-3.66	Aldosterone synthesis and secretion	KEGG pathways	ko04925	82	2	7161	22	GNAQ,ITPR2
2.580e-02	-3.66	Aldosterone synthesis and secretion	KEGG pathways	hsa04925	82	2	7161	22	GNAQ,ITPR2
2.581e-02	-3.66	SYNE1 (spectrin repeat containing nuclear envelope protein 1)	protein interactions	23345	97	2	19454	50	DSCAM,DISC1
2.585e-02	-3.66	KIFC3 (kinesin family member C3)	protein interactions	3801	248	3	19454	50	FCHSD2,DISC1,DSCAM
2.586e-02	-3.65	ZFPL1 (zinc finger protein like 1)	protein interactions	7542	438	4	19454	50	EPB41L2,PICALM,MAP4K4,DISC1
2.589e-02	-3.65	shoulder	COSMIC cancer mutations	shoulder	387	4	16828	49	ADAM28,FRMD4A,PTPRJ,GNAQ
2.591e-02	-3.65	skin-mucosal-malignant_melanoma-mucosal_lentiginous	COSMIC cancer mutations	skin-mucosal-malignant_melanoma-mucosal_lentiginous	9	1	16828	49	GNAQ
2.591e-02	-3.65	skin-chest-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-chest-malignant_melanoma-superficial_spreading	9	1	16828	49	GNAQ
2.591e-02	-3.65	sun_exposed_site	COSMIC cancer mutations	sun_exposed_site	9	1	16828	49	GNAQ
2.591e-02	-3.65	skin-ear-benign_melanocytic_nevus-melanocytic_tumour	COSMIC cancer mutations	skin-ear-benign_melanocytic_nevus-melanocytic_tumour	9	1	16828	49	GNAQ
2.591e-02	-3.65	mucosal_lentiginous	COSMIC cancer mutations	mucosal_lentiginous	9	1	16828	49	GNAQ
2.591e-02	-3.65	skin-benign_melanocytic_nevus-congenital	COSMIC cancer mutations	skin-benign_melanocytic_nevus-congenital	9	1	16828	49	GNAQ
2.591e-02	-3.65	melanotic	COSMIC cancer mutations	melanotic	9	1	16828	49	GNAQ
2.591e-02	-3.65	skin-mucosal-malignant_melanoma-nodular	COSMIC cancer mutations	skin-mucosal-malignant_melanoma-nodular	9	1	16828	49	GNAQ
2.594e-02	-3.65	intracellular monoatomic ion homeostasis	biological process	GO:0006873	437	4	18204	47	PICALM,SLC8A1,SLC9A9,DISC1
2.612e-02	-3.65	MYO19 (myosin XIX)	protein interactions	80179	249	3	19454	50	PICALM,SSH2,ZBTB20
2.612e-02	-3.65	TPR (translocated promoter region, nuclear basket protein)	protein interactions	7175	249	3	19454	50	DOCK8,EPB41L2,HDAC9
2.631e-02	-3.64	MED27 (mediator complex subunit 27)	protein interactions	9442	98	2	19454	50	MED13L,QKI
2.636e-02	-3.64	regulation of muscle system process	biological process	GO:0090257	249	3	18204	47	MEF2A,SLC8A1,DOCK4
2.640e-02	-3.63	chondroitin sulfate biosynthesis (late stages)	BIOCYC pathways	HUMAN_PWY-6567	8	1	902	3	CHST11
2.650e-02	-3.63	regulation of striated muscle cell differentiation	biological process	GO:0051153	98	2	18204	47	HDAC9,MEF2C
2.668e-02	-3.62	ENTH	interpro domains	IPR013809	10	1	18521	50	PICALM
2.668e-02	-3.62	MIR_motif	interpro domains	IPR016093	10	1	18521	50	ITPR2
2.668e-02	-3.62	MIR_dom_sf	interpro domains	IPR036300	10	1	18521	50	ITPR2
2.673e-02	-3.62	nuclear envelope lumen	cellular component	GO:0005641	11	1	19108	47	SORL1
2.673e-02	-3.62	platelet dense tubular network	cellular component	GO:0031094	11	1	19108	47	ITPR2
2.680e-02	-3.62	WASHC4 (WASH complex subunit 4)	protein interactions	23325	99	2	19454	50	DSCAM,LDLRAD4
2.700e-02	-3.61	Regulation of insulin secretion	REACTOME pathways	R-HSA-422356	80	2	10285	33	ITPR2,GNAQ
2.704e-02	-3.61	-	gene3d domains	2.60.40.2030	9	1	14470	44	SLC8A1
2.704e-02	-3.61	NCX, central ion-binding region	gene3d domains	1.20.1420.30	9	1	14470	44	SLC8A1
2.710e-02	-3.61	cell morphogenesis involved in neuron differentiation	biological process	GO:0048667	443	4	18204	47	MEF2C,DSCAM,PICALM,MEF2A
2.720e-02	-3.60	mucosal	COSMIC cancer mutations	mucosal	2009	11	16828	49	EPB41L2,ARHGAP22,SLC8A1,PLXDC2,ELMO1,ZFHX3,GNAQ,DIP2B,ADAM28,SORL1,APBB1IP
2.720e-02	-3.60	skin-mucosal-malignant_melanoma	COSMIC cancer mutations	skin-mucosal-malignant_melanoma	2009	11	16828	49	APBB1IP,SORL1,ADAM28,GNAQ,DIP2B,ZFHX3,ELMO1,PLXDC2,SLC8A1,ARHGAP22,EPB41L2
2.720e-02	-3.60	MIR	pfam domains	PF02815	10	1	17795	49	ITPR2
2.730e-02	-3.60	salt transmembrane transporter activity	molecular function	GO:1901702	10	1	18094	50	ABCC4
2.730e-02	-3.60	calcium:sodium antiporter activity	molecular function	GO:0005432	10	1	18094	50	SLC8A1
2.730e-02	-3.60	minor groove of adenine-thymine-rich DNA binding	molecular function	GO:0003680	10	1	18094	50	MEF2C
2.730e-02	-3.60	ATPase-coupled inorganic anion transmembrane transporter activity	molecular function	GO:0043225	10	1	18094	50	ABCC4
2.731e-02	-3.60	SUFU (SUFU negative regulator of hedgehog signaling)	protein interactions	51684	100	2	19454	50	LDLRAD4,DISC1
2.731e-02	-3.60	MED29 (mediator complex subunit 29)	protein interactions	55588	100	2	19454	50	MED13L,QKI
2.731e-02	-3.60	MUL1 (mitochondrial E3 ubiquitin protein ligase 1)	protein interactions	79594	100	2	19454	50	UBE2E2,DOCK4
2.731e-02	-3.60	MED10 (mediator complex subunit 10)	protein interactions	84246	100	2	19454	50	QKI,MED13L
2.737e-02	-3.60	pancreas-other-adenoma	COSMIC cancer mutations	pancreas-other-adenoma	224	3	16828	49	NAV3,KCNQ3,ATP8B4
2.769e-02	-3.59	pancreas-other-cystic_tumour	COSMIC cancer mutations	pancreas-other-cystic_tumour	89	2	16828	49	ZBTB20,SFMBT2
2.769e-02	-3.59	cystic_tumour	COSMIC cancer mutations	cystic_tumour	89	2	16828	49	SFMBT2,ZBTB20
2.781e-02	-3.58	LDB1 (LIM domain binding 1)	protein interactions	8861	101	2	19454	50	ZFHX3,DSCAM
2.792e-02	-3.58	RGS5 (regulator of G protein signaling 5)	protein interactions	8490	11	1	19454	50	GNAQ
2.792e-02	-3.58	TAL2 (TAL bHLH transcription factor 2)	protein interactions	6887	11	1	19454	50	TCF12
2.792e-02	-3.58	ZNF726 (zinc finger protein 726)	protein interactions	730087	11	1	19454	50	ARHGAP24
2.792e-02	-3.58	SPBC36B7.05c (putative ubiquitin-protein ligase E/phosphatidylinositol(3)-phosphate binding protein)	protein interactions	2540987	11	1	19454	50	UBE2E2
2.792e-02	-3.58	NYAP1 (neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1)	protein interactions	222950	11	1	19454	50	ARHGAP26
2.792e-02	-3.58	DAZ1 (deleted in azoospermia 1)	protein interactions	1617	11	1	19454	50	QKI
2.792e-02	-3.58	IL7 (interleukin 7)	protein interactions	3574	11	1	19454	50	QKI
2.792e-02	-3.58	CIMAP3 (ciliary microtubule associated protein 3)	protein interactions	128344	11	1	19454	50	GNAQ
2.792e-02	-3.58	TCF23 (transcription factor 23)	protein interactions	150921	11	1	19454	50	TCF12
2.792e-02	-3.58	NEUROD4 (neuronal differentiation 4)	protein interactions	58158	11	1	19454	50	TCF12
2.792e-02	-3.58	PYY (peptide YY)	protein interactions	5697	11	1	19454	50	PLXDC2
2.792e-02	-3.58	IRAG1 (inositol 1,4,5-triphosphate receptor associated 1)	protein interactions	10335	11	1	19454	50	ITPR2
2.792e-02	-3.58	CCDC141 (coiled-coil domain containing 141)	protein interactions	285025	11	1	19454	50	DISC1
2.794e-02	-3.58	regulation of plasma membrane bounded cell projection organization	biological process	GO:0120035	666	5	18204	47	DISC1,TBC1D22A,DIP2B,DSCAM,ARHGAP24
2.804e-02	-3.57	cyclic nucleotide transport	biological process	GO:0070729	11	1	18204	47	ABCC4
2.804e-02	-3.57	intracellular mRNA localization	biological process	GO:0008298	11	1	18204	47	QKI
2.804e-02	-3.57	cardiac chamber formation	biological process	GO:0003207	11	1	18204	47	MEF2C
2.804e-02	-3.57	pyramidal neuron development	biological process	GO:0021860	11	1	18204	47	DISC1
2.804e-02	-3.57	guanine nucleotide transport	biological process	GO:0001408	11	1	18204	47	ABCC4
2.804e-02	-3.57	synaptic vesicle budding	biological process	GO:0070142	11	1	18204	47	PICALM
2.804e-02	-3.57	phototransduction, visible light	biological process	GO:0007603	11	1	18204	47	GNAQ
2.804e-02	-3.57	secondary heart field specification	biological process	GO:0003139	11	1	18204	47	MEF2C
2.804e-02	-3.57	regulation of fear response	biological process	GO:1903365	11	1	18204	47	MEF2C
2.804e-02	-3.57	cellular response to caffeine	biological process	GO:0071313	11	1	18204	47	SLC8A1
2.804e-02	-3.57	positive regulation of cardiac muscle cell differentiation	biological process	GO:2000727	11	1	18204	47	MEF2C
2.804e-02	-3.57	regulation of skeletal muscle fiber development	biological process	GO:0048742	11	1	18204	47	HDAC9
2.804e-02	-3.57	tripeptide transport	biological process	GO:0042939	11	1	18204	47	ABCC4
2.804e-02	-3.57	synaptic vesicle clustering	biological process	GO:0097091	11	1	18204	47	SYNDIG1
2.804e-02	-3.57	urate transport	biological process	GO:0015747	11	1	18204	47	ABCC4
2.810e-02	-3.57	SYNCRIP (synaptotagmin binding cytoplasmic RNA interacting protein)	protein interactions	10492	669	5	19454	50	EPB41L2,MED13L,ARHGAP24,QKI,DISC1
2.822e-02	-3.57	anatomical structure development	biological process	GO:0048856	5207	20	18204	47	ZFHX3,MAP4K4,DSCAM,MEF2C,QKI,ARHGAP24,KCNQ3,CHST11,ZSWIM6,TCF12,DISC1,ARHGAP22,PICALM,SLC8A1,NAV3,HDAC9,ARHGAP26,PTPRJ,MEF2A,DIP2B
2.830e-02	-3.56	positive regulation of growth	biological process	GO:0045927	256	3	18204	47	DSCAM,DISC1,MEF2C
2.831e-02	-3.56	ankle	COSMIC cancer mutations	ankle	398	4	16828	49	GNAQ,ARHGAP22,PTPRJ,ADAM28
2.832e-02	-3.56	human chr10p12.31	chromosome location	human chr10p12.31	15	1	26134	50	PLXDC2
2.832e-02	-3.56	human chr4q31.1	chromosome location	human chr4q31.1	15	1	26134	50	MAML3
2.832e-02	-3.56	human chr9p24.3	chromosome location	human chr9p24.3	15	1	26134	50	DOCK8
2.832e-02	-3.56	human chr11q14.2	chromosome location	human chr11q14.2	15	1	26134	50	PICALM
2.832e-02	-3.56	human chr12q21.2	chromosome location	human chr12q21.2	15	1	26134	50	NAV3
2.832e-02	-3.56	ZSCAN21 (zinc finger and SCAN domain containing 21)	protein interactions	7589	102	2	19454	50	SORL1,ARHGAP24
2.832e-02	-3.56	CHRNB2 (cholinergic receptor nicotinic beta 2 subunit)	protein interactions	1141	102	2	19454	50	ST6GALNAC3,CHST11
2.832e-02	-3.56	TTC23 (tetratricopeptide repeat domain 23)	protein interactions	64927	102	2	19454	50	ZFHX3,DISC1
2.832e-02	-3.56	H3C15 (H3 clustered histone 15)	protein interactions	333932	102	2	19454	50	MAP4K4,HDAC9
2.836e-02	-3.56	MIR	prosite domains	PS50919	10	1	12186	35	ITPR2
2.851e-02	-3.56	recycling endosome membrane	cellular component	GO:0055038	107	2	19108	47	SLC9A9,SORL1
2.852e-02	-3.56	Sodium/Proton exchangers	REACTOME pathways	R-HSA-425986	9	1	10285	33	SLC9A9
2.865e-02	-3.55	urinary_tract-bladder-carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma	14050	46	16828	49	MEF2C,MAML2,DOCK8,MAML3,DIP2B,FRMD4A,ITPR2,TBC1D22A,SLC9A9,NAV3,HS3ST4,APBB1IP,ADAM28,ZFHX3,ST6GALNAC3,SYNDIG1,PICALM,MED13L,TCF12,QKI,KCNQ3,HDAC9,ARHGAP26,ELMO1,MEF2A,SSH2,ZBTB20,DOCK4,EPB41L2,SLC8A1,SFMBT2,CHST11,FCHSD2,UBE2E2,SORL1,GNAQ,ATP8B4,DSCAM,PLXDC2,ANKRD44,PTPRJ,ABCC4,MAP4K4,ST6GAL1,ARHGAP24,ARHGAP22
2.875e-02	-3.55	skin-shoulder-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-superficial_spreading	10	1	16828	49	GNAQ
2.875e-02	-3.55	chiasm	COSMIC cancer mutations	chiasm	10	1	16828	49	QKI
2.875e-02	-3.55	intradermal	COSMIC cancer mutations	intradermal	10	1	16828	49	GNAQ
2.875e-02	-3.55	melanocytic_tumour	COSMIC cancer mutations	melanocytic_tumour	10	1	16828	49	GNAQ
2.875e-02	-3.55	elbow	COSMIC cancer mutations	elbow	10	1	16828	49	GNAQ
2.875e-02	-3.55	eye-conjunctiva-malignant_melanoma	COSMIC cancer mutations	eye-conjunctiva-malignant_melanoma	10	1	16828	49	GNAQ
2.875e-02	-3.55	skin-back-malignant_melanoma-nodular	COSMIC cancer mutations	skin-back-malignant_melanoma-nodular	10	1	16828	49	GNAQ
2.875e-02	-3.55	skin-abdomen-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-superficial_spreading	10	1	16828	49	GNAQ
2.884e-02	-3.55	NEUROG3 (neurogenin 3)	protein interactions	50674	103	2	19454	50	TCF12,MAP4K4
2.887e-02	-3.54	small GTPase-mediated signal transduction	biological process	GO:0007264	258	3	18204	47	DOCK8,ELMO1,DOCK4
2.892e-02	-3.54	NAHEXCHNGR	prints domains	PR01084	9	1	5227	17	SLC9A9
2.892e-02	-3.54	Isothipendyl H1-Antihistamine Action	SMPDB pathways	SMP0059716	8	1	1369	5	GNAQ
2.892e-02	-3.54	Quifenadine H1-Antihistamine Action	SMPDB pathways	SMP0060743	8	1	1369	5	GNAQ
2.892e-02	-3.54	Alimemazine H1-Antihistamine Action	SMPDB pathways	SMP0059689	8	1	1369	5	GNAQ
2.892e-02	-3.54	Tolpropamine H1-Antihistamine Action	SMPDB pathways	SMP0062621	8	1	1369	5	GNAQ
2.892e-02	-3.54	Epinastine H1-Antihistamine Action	SMPDB pathways	SMP0061191	8	1	1369	5	GNAQ
2.892e-02	-3.54	Doxylamine H1-Antihistamine Action	SMPDB pathways	SMP0058803	8	1	1369	5	GNAQ
2.892e-02	-3.54	Oxatomide H1-Antihistamine Action	SMPDB pathways	SMP0059044	8	1	1369	5	GNAQ
2.892e-02	-3.54	Antazoline H1-Antihistamine Action	SMPDB pathways	SMP0057584	8	1	1369	5	GNAQ
2.892e-02	-3.54	Ebastine H1-Antihistamine Action	SMPDB pathways	SMP0060204	8	1	1369	5	GNAQ
2.892e-02	-3.54	Tripelennamine H1-Antihistamine Action	SMPDB pathways	SMP0057587	8	1	1369	5	GNAQ
2.892e-02	-3.54	Doxepin H1-Antihistamine Action	SMPDB pathways	SMP0059872	8	1	1369	5	GNAQ
2.892e-02	-3.54	Levocetirizine H1-Antihistamine Action	SMPDB pathways	SMP0059114	8	1	1369	5	GNAQ
2.892e-02	-3.54	Hydroxyethylpromethazine H1-Antihistamine Action	SMPDB pathways	SMP0059710	8	1	1369	5	GNAQ
2.892e-02	-3.54	Bromodiphenhydramine H1-Antihistamine Action	SMPDB pathways	SMP0058813	8	1	1369	5	GNAQ
2.892e-02	-3.54	Promethazine H1-Antihistamine Action	SMPDB pathways	SMP0059211	8	1	1369	5	GNAQ
2.892e-02	-3.54	Azelastine H1-Antihistamine Action	SMPDB pathways	SMP0060741	8	1	1369	5	GNAQ
2.892e-02	-3.54	Latrepirdine H1-Antihistamine Action	SMPDB pathways	SMP0062623	8	1	1369	5	GNAQ
2.892e-02	-3.54	Meclizine H1-Antihistamine Action	SMPDB pathways	SMP0058956	8	1	1369	5	GNAQ
2.892e-02	-3.54	Pheniramine H1-Antihistamine Action	SMPDB pathways	SMP0056662	8	1	1369	5	GNAQ
2.892e-02	-3.54	Clemastine H1-Antihistamine Action	SMPDB pathways	SMP0058891	8	1	1369	5	GNAQ
2.892e-02	-3.54	Pyrrobutamine H1-Antihistamine Action	SMPDB pathways	SMP0062887	8	1	1369	5	GNAQ
2.892e-02	-3.54	Homochlorcyclizine H1-Antihistamine Action	SMPDB pathways	SMP0062795	8	1	1369	5	GNAQ
2.892e-02	-3.54	Chlorphenoxamine H1-Antihistamine Action	SMPDB pathways	SMP0058903	8	1	1369	5	GNAQ
2.892e-02	-3.54	Quetiapine H1-Antihistamine Action	SMPDB pathways	SMP0062884	8	1	1369	5	GNAQ
2.892e-02	-3.54	Tritoqualine H1-Antihistamine Action	SMPDB pathways	SMP0062895	8	1	1369	5	GNAQ
2.892e-02	-3.54	Acrivastine H1-Antihistamine Action	SMPDB pathways	SMP0059881	8	1	1369	5	GNAQ
2.892e-02	-3.54	Deptropine H1-Antihistamine Action	SMPDB pathways	SMP0062883	8	1	1369	5	GNAQ
2.892e-02	-3.54	Oxomemazine H1-Antihistamine Action	SMPDB pathways	SMP0059738	8	1	1369	5	GNAQ
2.892e-02	-3.54	Phenbenzamine H1-Antihistamine Action	SMPDB pathways	SMP0059702	8	1	1369	5	GNAQ
2.892e-02	-3.54	Desloratadine H1-Antihistamine Action	SMPDB pathways	SMP0060201	8	1	1369	5	GNAQ
2.892e-02	-3.54	Triprolidine H1-Antihistamine Action	SMPDB pathways	SMP0057581	8	1	1369	5	GNAQ
2.892e-02	-3.54	Thenyldiamine H1-Antihistamine Action	SMPDB pathways	SMP0062624	8	1	1369	5	GNAQ
2.892e-02	-3.54	Methdilazine H1-Antihistamine Action	SMPDB pathways	SMP0059730	8	1	1369	5	GNAQ
2.892e-02	-3.54	Alcaftadine H1-Antihistamine Action	SMPDB pathways	SMP0062881	8	1	1369	5	GNAQ
2.892e-02	-3.54	Dexchlorpheniramine H1-Antihistamine Action	SMPDB pathways	SMP0056811	8	1	1369	5	GNAQ
2.892e-02	-3.54	Carbinoxamine H1-Antihistamine Action	SMPDB pathways	SMP0058797	8	1	1369	5	GNAQ
2.892e-02	-3.54	Diphenhydramine H1-Antihistamine Action	SMPDB pathways	SMP0058785	8	1	1369	5	GNAQ
2.892e-02	-3.54	Betahistine H1-Antihistamine Action	SMPDB pathways	SMP0060744	8	1	1369	5	GNAQ
2.892e-02	-3.54	Chlorcyclizine H1-Antihistamine Action	SMPDB pathways	SMP0058931	8	1	1369	5	GNAQ
2.892e-02	-3.54	Flunarizine H1-Antihistamine Action	SMPDB pathways	SMP0061047	8	1	1369	5	GNAQ
2.892e-02	-3.54	Mepyramine H1-Antihistamine Action	SMPDB pathways	SMP0057583	8	1	1369	5	GNAQ
2.892e-02	-3.54	Diphenylpyraline H1-Antihistamine Action	SMPDB pathways	SMP0058908	8	1	1369	5	GNAQ
2.892e-02	-3.54	Buclizine H1-Antihistamine Action	SMPDB pathways	SMP0058964	8	1	1369	5	GNAQ
2.892e-02	-3.54	Rupatadine H1-Antihistamine Action	SMPDB pathways	SMP0060235	8	1	1369	5	GNAQ
2.892e-02	-3.54	Phenindamine H1-Antihistamine Action	SMPDB pathways	SMP0061190	8	1	1369	5	GNAQ
2.892e-02	-3.54	Loratadine H1-Antihistamine Action	SMPDB pathways	SMP0060195	8	1	1369	5	GNAQ
2.892e-02	-3.54	Bamipine H1-Antihistamine Action	SMPDB pathways	SMP0062882	8	1	1369	5	GNAQ
2.892e-02	-3.54	Emedastine H1-Antihistamine Action	SMPDB pathways	SMP0061040	8	1	1369	5	GNAQ
2.892e-02	-3.54	Mebhydrolin H1-Antihistamine Action	SMPDB pathways	SMP0061052	8	1	1369	5	GNAQ
2.892e-02	-3.54	Phenyltoloxamine H1-Antihistamine Action	SMPDB pathways	SMP0058916	8	1	1369	5	GNAQ
2.892e-02	-3.54	Olopatadine H1-Antihistamine Action	SMPDB pathways	SMP0060740	8	1	1369	5	GNAQ
2.892e-02	-3.54	Dimetindene H1-Antihistamine Action	SMPDB pathways	SMP0057582	8	1	1369	5	GNAQ
2.892e-02	-3.54	Histapyrrodine H1-Antihistamine Action	SMPDB pathways	SMP0058732	8	1	1369	5	GNAQ
2.892e-02	-3.54	Orphenadrine H1-Antihistamine Action	SMPDB pathways	SMP0058808	8	1	1369	5	GNAQ
2.892e-02	-3.54	Cyproheptadine H1-Antihistamine Action	SMPDB pathways	SMP0059694	8	1	1369	5	GNAQ
2.892e-02	-3.54	Propiomazine H1-Antihistamine Action	SMPDB pathways	SMP0062625	8	1	1369	5	GNAQ
2.892e-02	-3.54	Cetirizine H1-Antihistamine Action	SMPDB pathways	SMP0059058	8	1	1369	5	GNAQ
2.892e-02	-3.54	Mizolastine H1-Antihistamine Action	SMPDB pathways	SMP0060230	8	1	1369	5	GNAQ
2.892e-02	-3.54	Azatadine H1-Antihistamine Action	SMPDB pathways	SMP0059865	8	1	1369	5	GNAQ
2.892e-02	-3.54	Terfenadine H1-Antihistamine Action	SMPDB pathways	SMP0060208	8	1	1369	5	GNAQ
2.892e-02	-3.54	Cinnarizine H1-Antihistamine Action	SMPDB pathways	SMP0059110	8	1	1369	5	GNAQ
2.892e-02	-3.54	Chlorphenamine H1-Antihistamine Action	SMPDB pathways	SMP0056661	8	1	1369	5	GNAQ
2.892e-02	-3.54	Talastine H1-Antihistamine Action	SMPDB pathways	SMP0057586	8	1	1369	5	GNAQ
2.892e-02	-3.54	Histamine H1 Receptor Activation	SMPDB pathways	SMP0063452	8	1	1369	5	GNAQ
2.892e-02	-3.54	Thiazinamium H1-Antihistamine Action	SMPDB pathways	SMP0060742	8	1	1369	5	GNAQ
2.892e-02	-3.54	Dexbrompheniramine H1-Antihistamine Action	SMPDB pathways	SMP0057580	8	1	1369	5	GNAQ
2.892e-02	-3.54	Levocabastine H1-Antihistamine Action	SMPDB pathways	SMP0060224	8	1	1369	5	GNAQ
2.892e-02	-3.54	Thenalidine H1-Antihistamine Action	SMPDB pathways	SMP0062894	8	1	1369	5	GNAQ
2.892e-02	-3.54	Mirtazapine H1-Antihistamine Action	SMPDB pathways	SMP0062885	8	1	1369	5	GNAQ
2.892e-02	-3.54	Thonzylamine H1-Antihistamine Action	SMPDB pathways	SMP0058769	8	1	1369	5	GNAQ
2.892e-02	-3.54	Cyclizine H1-Antihistamine Action	SMPDB pathways	SMP0058923	8	1	1369	5	GNAQ
2.892e-02	-3.54	Temelastine H1-Antihistamine Action	SMPDB pathways	SMP0062880	8	1	1369	5	GNAQ
2.892e-02	-3.54	Hydroxyzine H1-Antihistamine Action	SMPDB pathways	SMP0058936	8	1	1369	5	GNAQ
2.892e-02	-3.54	Methapyrilene H1-Antihistamine Action	SMPDB pathways	SMP0058741	8	1	1369	5	GNAQ
2.892e-02	-3.54	Bepotastine H1-Antihistamine Action	SMPDB pathways	SMP0060058	8	1	1369	5	GNAQ
2.892e-02	-3.54	Fexofenadine H1-Antihistamine Action	SMPDB pathways	SMP0060218	8	1	1369	5	GNAQ
2.892e-02	-3.54	Ketotifen H1-Antihistamine Action	SMPDB pathways	SMP0059868	8	1	1369	5	GNAQ
2.892e-02	-3.54	Bilastine H1-Antihistamine Action	SMPDB pathways	SMP0060170	8	1	1369	5	GNAQ
2.892e-02	-3.54	Fenethazine H1-Antihistamine Action	SMPDB pathways	SMP0059707	8	1	1369	5	GNAQ
2.892e-02	-3.54	Chloropyramine H1-Antihistamine Action	SMPDB pathways	SMP0057585	8	1	1369	5	GNAQ
2.892e-02	-3.54	Mequitazine H1-Antihistamine Action	SMPDB pathways	SMP0059720	8	1	1369	5	GNAQ
2.892e-02	-3.54	Brompheniramine H1-Antihistamine Action	SMPDB pathways	SMP0057579	8	1	1369	5	GNAQ
2.892e-02	-3.54	Clocinizine H1-Antihistamine Action	SMPDB pathways	SMP0062788	8	1	1369	5	GNAQ
2.892e-02	-3.54	Astemizole H1-Antihistamine Action	SMPDB pathways	SMP0059897	8	1	1369	5	GNAQ
2.892e-02	-3.54	Pimethixene H1-Antihistamine Action	SMPDB pathways	SMP0062886	8	1	1369	5	GNAQ
2.892e-02	-3.54	Embramine H1-Antihistamine Action	SMPDB pathways	SMP0062622	8	1	1369	5	GNAQ
2.905e-02	-3.54	regulation of biomineral tissue development	biological process	GO:0070167	103	2	18204	47	SLC8A1,MEF2C
2.908e-02	-3.54	regulation of cell communication	biological process	GO:0010646	3541	15	18204	47	MAP4K4,KCNQ3,CHST11,ARHGAP24,MEF2C,DOCK8,GNAQ,SLC8A1,ARHGAP22,PICALM,DISC1,SORL1,LDLRAD4,ARHGAP26,PTPRJ
2.913e-02	-3.54	Golgi medial cisterna	cellular component	GO:0005797	12	1	19108	47	ST6GAL1
2.927e-02	-3.53	Calx_beta	smart domains	SM00237	8	1	9717	36	SLC8A1
2.927e-02	-3.53	ZnF_AN1	smart domains	SM00154	8	1	9717	36	ZFAND3
2.931e-02	-3.53	His_deacetylse_dom_sf	interpro domains	IPR037138	11	1	18521	50	HDAC9
2.931e-02	-3.53	His_deacetylse_dom	interpro domains	IPR023801	11	1	18521	50	HDAC9
2.931e-02	-3.53	NST/OST	interpro domains	IPR037359	11	1	18521	50	HS3ST4
2.931e-02	-3.53	His_deacetylse	interpro domains	IPR000286	11	1	18521	50	HDAC9
2.931e-02	-3.53	Cation/H_exchanger_CPA1	interpro domains	IPR018422	11	1	18521	50	SLC9A9
2.932e-02	-3.53	Protein tyrosine phosphatase superfamily	gene3d domains	3.90.190.10	88	2	14470	44	PTPRJ,SSH2
2.940e-02	-3.53	response to organonitrogen compound	biological process	GO:0010243	915	6	18204	47	HDAC9,SLC8A1,ITPR2,GNAQ,TCF12,MEF2C
2.941e-02	-3.53	Gap junction	KEGG pathways	ko04540	88	2	7161	22	ITPR2,GNAQ
2.941e-02	-3.53	Gap junction	KEGG pathways	hsa04540	88	2	7161	22	GNAQ,ITPR2
2.946e-02	-3.52	DIRAS3 (DIRAS family GTPase 3)	protein interactions	9077	261	3	19454	50	EPB41L2,MAP4K4,PICALM
2.948e-02	-3.52	distal axon	cellular component	GO:0150034	273	3	19108	47	DISC1,SLC8A1,DSCAM
2.955e-02	-3.52	Toll Like Receptor 5 (TLR5) Cascade	REACTOME pathways	R-HSA-168176	84	2	10285	33	MEF2A,MEF2C
2.955e-02	-3.52	MyD88 cascade initiated on plasma membrane	REACTOME pathways	R-HSA-975871	84	2	10285	33	MEF2C,MEF2A
2.955e-02	-3.52	Toll Like Receptor 10 (TLR10) Cascade	REACTOME pathways	R-HSA-168142	84	2	10285	33	MEF2C,MEF2A
2.958e-02	-3.52	inorganic cation import across plasma membrane	biological process	GO:0098659	104	2	18204	47	SLC9A9,SLC8A1
2.958e-02	-3.52	inorganic ion import across plasma membrane	biological process	GO:0099587	104	2	18204	47	SLC8A1,SLC9A9
2.963e-02	-3.52	regulation of molecular function	biological process	GO:0065009	2005	10	18204	47	PTPRJ,ARHGAP24,MEF2C,GNAQ,TBC1D22A,DOCK8,SLC8A1,ARHGAP22,DISC1,MAP4K4
2.973e-02	-3.52	regulation of blood circulation	biological process	GO:1903522	261	3	18204	47	DOCK4,SLC8A1,MEF2A
2.988e-02	-3.51	MED26 (mediator complex subunit 26)	protein interactions	9441	105	2	19454	50	QKI,MED13L
2.988e-02	-3.51	WDR59 (WD repeat domain 59)	protein interactions	79726	105	2	19454	50	DSCAM,EPB41L2
2.988e-02	-3.51	Hist_deacetyl	pfam domains	PF00850	11	1	17795	49	HDAC9
2.999e-02	-3.51	oligopeptide transmembrane transporter activity	molecular function	GO:0035673	11	1	18094	50	ABCC4
2.999e-02	-3.51	clathrin heavy chain binding	molecular function	GO:0032050	11	1	18094	50	PICALM
3.000e-02	-3.51	-	gene3d domains	6.10.140.1330	10	1	14470	44	SLC9A9
3.010e-02	-3.50	regulation of postsynapse organization	biological process	GO:0099175	105	2	18204	47	ARHGAP22,DISC1
3.018e-02	-3.50	human chr5q12.1	chromosome location	human chr5q12.1	16	1	26134	50	ZSWIM6
3.018e-02	-3.50	human chr2p22.1	chromosome location	human chr2p22.1	16	1	26134	50	SLC8A1
3.023e-02	-3.50	cell migration	biological process	GO:0016477	921	6	18204	47	ARHGAP24,DOCK4,DISC1,MEF2C,DOCK8,SORL1
3.033e-02	-3.50	synaptic signaling	biological process	GO:0099536	459	4	18204	47	KCNQ3,FCHSD2,MEF2C,GNAQ
3.039e-02	-3.49	skin-hand-carcinoma-squamous_cell_carcinoma	COSMIC cancer mutations	skin-hand-carcinoma-squamous_cell_carcinoma	407	4	16828	49	ATP8B4,DSCAM,SFMBT2,DIP2B
3.040e-02	-3.49	THRA (thyroid hormone receptor alpha)	protein interactions	7067	106	2	19454	50	MEF2A,ARHGAP24
3.042e-02	-3.49	LOC102724560 (cystathionine beta-synthase like)	protein interactions	102724560	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	NUDT4 (nudix hydrolase 4)	protein interactions	11163	12	1	19454	50	DISC1
3.042e-02	-3.49	GCSAML (germinal center associated signaling and motility like)	protein interactions	148823	12	1	19454	50	PLXDC2
3.042e-02	-3.49	TCF21 (transcription factor 21)	protein interactions	6943	12	1	19454	50	TCF12
3.042e-02	-3.49	TM7SF2 (transmembrane 7 superfamily member 2)	protein interactions	7108	12	1	19454	50	DISC1
3.042e-02	-3.49	ADGRB3 (adhesion G protein-coupled receptor B3)	protein interactions	577	12	1	19454	50	ELMO1
3.042e-02	-3.49	ISG20 (interferon stimulated exonuclease gene 20)	protein interactions	3669	12	1	19454	50	GNAQ
3.042e-02	-3.49	ZNF26 (zinc finger protein 26)	protein interactions	7574	12	1	19454	50	SORL1
3.042e-02	-3.49	C8orf76 (chromosome 8 open reading frame 76)	protein interactions	84933	12	1	19454	50	DISC1
3.042e-02	-3.49	TCF15 (transcription factor 15)	protein interactions	6939	12	1	19454	50	TCF12
3.042e-02	-3.49	ZNF91 (zinc finger protein 91)	protein interactions	7644	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	ZNF843 (zinc finger protein 843)	protein interactions	283933	12	1	19454	50	GNAQ
3.042e-02	-3.49	ZNF235 (zinc finger protein 235)	protein interactions	9310	12	1	19454	50	ARHGAP24
3.042e-02	-3.49	ZNF584 (zinc finger protein 584)	protein interactions	201514	12	1	19454	50	SORL1
3.042e-02	-3.49	HNRNPCL3 (heterogeneous nuclear ribonucleoprotein C like 3)	protein interactions	649330	12	1	19454	50	MAP4K4
3.042e-02	-3.49	upper_aerodigestive_tract	COSMIC cancer mutations	upper_aerodigestive_tract	13181	44	16828	49	PICALM,ARHGAP24,ARHGAP22,SYNDIG1,MAP4K4,ST6GAL1,ST6GALNAC3,PTPRJ,ANKRD44,ATP8B4,DSCAM,ZFHX3,GNAQ,APBB1IP,UBE2E2,SORL1,ADAM28,DISC1,FCHSD2,CHST11,NAV3,SLC8A1,SFMBT2,DOCK4,EPB41L2,SLC9A9,ZBTB20,SSH2,ZSWIM6,TBC1D22A,FRMD4A,ITPR2,ARHGAP26,ELMO1,DIP2B,MAML3,HDAC9,QKI,KCNQ3,DOCK8,TCF12,MED13L,MAML2,MEF2C
3.044e-02	-3.49	Prot-tyrosine_phosphatase-like	interpro domains	IPR029021	101	2	18521	50	SSH2,PTPRJ
3.056e-02	-3.49	negative regulation of smooth muscle contraction	biological process	GO:0045986	12	1	18204	47	DOCK4
3.056e-02	-3.49	negative regulation of protein localization to cell surface	biological process	GO:2000009	12	1	18204	47	PICALM
3.056e-02	-3.49	excitatory chemical synaptic transmission	biological process	GO:0098976	12	1	18204	47	KCNQ3
3.056e-02	-3.49	heart field specification	biological process	GO:0003128	12	1	18204	47	MEF2C
3.056e-02	-3.49	positive regulation of keratinocyte migration	biological process	GO:0051549	12	1	18204	47	MAP4K4
3.056e-02	-3.49	negative regulation of inclusion body assembly	biological process	GO:0090084	12	1	18204	47	SORL1
3.056e-02	-3.49	microglia differentiation	biological process	GO:0014004	12	1	18204	47	QKI
3.056e-02	-3.49	N-acetylneuraminate metabolic process	biological process	GO:0006054	12	1	18204	47	ST6GAL1
3.056e-02	-3.49	cellular response to antibiotic	biological process	GO:0071236	12	1	18204	47	MEF2C
3.056e-02	-3.49	oligopeptide transmembrane transport	biological process	GO:0035672	12	1	18204	47	ABCC4
3.056e-02	-3.49	positive regulation of protein localization to endosome	biological process	GO:1905668	12	1	18204	47	SORL1
3.056e-02	-3.49	negative regulation of vasoconstriction	biological process	GO:0045906	12	1	18204	47	DOCK4
3.066e-02	-3.48	Salivary secretion	KEGG pathways	ko04970	90	2	7161	22	GNAQ,ITPR2
3.066e-02	-3.48	Salivary secretion	KEGG pathways	hsa04970	90	2	7161	22	GNAQ,ITPR2
3.070e-02	-3.48	regulation of cell projection organization	biological process	GO:0031344	683	5	18204	47	DISC1,TBC1D22A,DIP2B,DSCAM,ARHGAP24
3.074e-02	-3.48	organelle membrane	cellular component	GO:0031090	3742	15	19108	47	ARHGAP26,GNAQ,PTPRJ,LDLRAD4,ST6GAL1,ATP8B4,ITPR2,SORL1,CHST11,ST6GALNAC3,NAV3,ABCC4,HS3ST4,SLC9A9,SYNDIG1
3.086e-02	-3.48	Fcgamma receptor (FCGR) dependent phagocytosis	REACTOME pathways	R-HSA-2029480	86	2	10285	33	ELMO1,ITPR2
3.093e-02	-3.48	KIFAP3 (kinesin associated protein 3)	protein interactions	22920	107	2	19454	50	DISC1,GNAQ
3.103e-02	-3.47	tube morphogenesis	biological process	GO:0035239	685	5	18204	47	ARHGAP24,QKI,ARHGAP22,PTPRJ,MEF2C
3.118e-02	-3.47	regulation of membrane potential	biological process	GO:0042391	463	4	18204	47	KCNQ3,SLC8A1,MEF2C,GNAQ
3.119e-02	-3.47	protein tyrosine phosphatase activity	molecular function	GO:0004725	100	2	18094	50	PTPRJ,SSH2
3.120e-02	-3.47	endometrium-carcinoma-endometrioid_carcinoma	COSMIC cancer mutations	endometrium-carcinoma-endometrioid_carcinoma	15680	49	16828	49	APBB1IP,ADAM28,HS3ST4,NAV3,PICALM,SYNDIG1,ST6GALNAC3,ZFHX3,DIP2B,MAML3,DOCK8,MAML2,MEF2C,SLC9A9,TBC1D22A,FRMD4A,ITPR2,GNAQ,UBE2E2,DISC1,SORL1,FCHSD2,CHST11,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4,ABCC4,PLXDC2,PTPRJ,ANKRD44,ATP8B4,DSCAM,HDAC9,QKI,KCNQ3,TCF12,MED13L,SLC8A1,SFMBT2,DOCK4,EPB41L2,ZFAND3,ZBTB20,SSH2,ZSWIM6,ELMO1,ARHGAP26,MEF2A
3.137e-02	-3.46	cell morphogenesis	biological process	GO:0000902	687	5	18204	47	MEF2C,MAP4K4,DSCAM,PICALM,MEF2A
3.139e-02	-3.46	cellular response to organic cyclic compound	biological process	GO:0071407	464	4	18204	47	MEF2C,GNAQ,SLC8A1,ITPR2
3.147e-02	-3.46	GGT7 (gamma-glutamyltransferase 7)	protein interactions	2686	108	2	19454	50	ARHGAP24,ST6GALNAC3
3.149e-02	-3.46	PFN1 (profilin 1)	protein interactions	5216	466	4	19454	50	DOCK4,ARHGAP24,DOCK8,APBB1IP
3.152e-02	-3.46	early phagosome	cellular component	GO:0032009	13	1	19108	47	SLC9A9
3.154e-02	-3.46	hemopoiesis	biological process	GO:0030097	688	5	18204	47	HDAC9,PICALM,QKI,PTPRJ,MEF2C
3.158e-02	-3.46	congenital	COSMIC cancer mutations	congenital	11	1	16828	49	GNAQ
3.158e-02	-3.46	skin-back-malignant_melanoma-superficial_spreading	COSMIC cancer mutations	skin-back-malignant_melanoma-superficial_spreading	11	1	16828	49	GNAQ
3.158e-02	-3.46	skin-scalp-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-scalp-malignant_melanoma-lentigo_maligna	11	1	16828	49	GNAQ
3.158e-02	-3.46	central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_I	11	1	16828	49	GNAQ
3.158e-02	-3.46	bone-extraskeletal-chondrosarcoma-myxoid	COSMIC cancer mutations	bone-extraskeletal-chondrosarcoma-myxoid	11	1	16828	49	TCF12
3.158e-02	-3.46	skin-back-benign_melanocytic_nevus	COSMIC cancer mutations	skin-back-benign_melanocytic_nevus	11	1	16828	49	GNAQ
3.164e-02	-3.45	Acetylcholine regulates insulin secretion	REACTOME pathways	R-HSA-399997	10	1	10285	33	GNAQ
3.171e-02	-3.45	cellular homeostasis	biological process	GO:0019725	689	5	18204	47	DISC1,ZBTB20,SLC9A9,SLC8A1,PICALM
3.183e-02	-3.45	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis	413	4	16828	49	MED13L,ST6GAL1,MAP4K4,TCF12
3.183e-02	-3.45	myelofibrosis	COSMIC cancer mutations	myelofibrosis	413	4	16828	49	ST6GAL1,MAP4K4,MED13L,TCF12
3.192e-02	-3.44	Th1 and Th2 cell differentiation	KEGG pathways	ko04658	92	2	7161	22	MAML2,MAML3
3.192e-02	-3.44	GnRH signaling pathway	KEGG pathways	ko04912	92	2	7161	22	ITPR2,GNAQ
3.192e-02	-3.44	GnRH signaling pathway	KEGG pathways	hsa04912	92	2	7161	22	ITPR2,GNAQ
3.192e-02	-3.44	Th1 and Th2 cell differentiation	KEGG pathways	hsa04658	92	2	7161	22	MAML2,MAML3
3.193e-02	-3.44	Sulfotransferase	interpro domains	IPR005331	12	1	18521	50	CHST11
3.210e-02	-3.44	positive regulation of molecular function	biological process	GO:0044093	1192	7	18204	47	ARHGAP22,MAP4K4,ARHGAP24,DOCK8,GNAQ,TBC1D22A,MEF2C
3.219e-02	-3.44	endometrioid_carcinoma	COSMIC cancer mutations	endometrioid_carcinoma	15690	49	16828	49	ST6GAL1,MAP4K4,ARHGAP22,ARHGAP24,DSCAM,ATP8B4,ANKRD44,PTPRJ,PLXDC2,ABCC4,FCHSD2,SORL1,DISC1,UBE2E2,GNAQ,CHST11,ZBTB20,ZFAND3,EPB41L2,DOCK4,SFMBT2,SLC8A1,MEF2A,ELMO1,ARHGAP26,ZSWIM6,SSH2,KCNQ3,QKI,HDAC9,MED13L,TCF12,SYNDIG1,PICALM,ZFHX3,ST6GALNAC3,ADAM28,APBB1IP,NAV3,HS3ST4,SLC9A9,ITPR2,FRMD4A,TBC1D22A,DOCK8,MAML3,DIP2B,MEF2C,MAML2
3.224e-02	-3.43	positive regulation of tumor necrosis factor production	biological process	GO:0032760	109	2	18204	47	ZBTB20,PTPRJ
3.239e-02	-3.43	endometrium	COSMIC cancer mutations	endometrium	15692	49	16828	49	CHST11,DISC1,SORL1,UBE2E2,FCHSD2,GNAQ,DSCAM,ATP8B4,ABCC4,PTPRJ,ANKRD44,PLXDC2,ARHGAP22,ARHGAP24,ST6GAL1,MAP4K4,TCF12,MED13L,KCNQ3,QKI,HDAC9,MEF2A,ARHGAP26,ELMO1,SSH2,ZSWIM6,ZBTB20,ZFAND3,SFMBT2,SLC8A1,EPB41L2,DOCK4,NAV3,HS3ST4,ADAM28,APBB1IP,ZFHX3,ST6GALNAC3,PICALM,SYNDIG1,MEF2C,MAML2,DOCK8,DIP2B,MAML3,ITPR2,FRMD4A,TBC1D22A,SLC9A9
3.241e-02	-3.43	GNB1 (G protein subunit beta 1)	protein interactions	2782	271	3	19454	50	SLC9A9,GNAQ,DISC1
3.245e-02	-3.43	skin-knee-malignant_melanoma	COSMIC cancer mutations	skin-knee-malignant_melanoma	97	2	16828	49	PTPRJ,ADAM28
3.256e-02	-3.42	Sulfotransfer_2	pfam domains	PF03567	12	1	17795	49	CHST11
3.256e-02	-3.42	BAR_3	pfam domains	PF16746	12	1	17795	49	ARHGAP26
3.267e-02	-3.42	prostaglandin transmembrane transporter activity	molecular function	GO:0015132	12	1	18094	50	ABCC4
3.267e-02	-3.42	gamma-catenin binding	molecular function	GO:0045295	12	1	18094	50	PTPRJ
3.267e-02	-3.42	inositol 1,4,5 trisphosphate binding	molecular function	GO:0070679	12	1	18094	50	ITPR2
3.267e-02	-3.42	cAMP response element binding	molecular function	GO:0035497	12	1	18094	50	TCF12
3.279e-02	-3.42	large_intestine-colon-carcinoma	COSMIC cancer mutations	large_intestine-colon-carcinoma	2612	13	16828	49	FRMD4A,DSCAM,ZFHX3,ITPR2,TBC1D22A,PTPRJ,SLC8A1,PICALM,ARHGAP22,NAV3,UBE2E2,SORL1,GNAQ
3.287e-02	-3.42	MBT	smart domains	SM00561	9	1	9717	36	SFMBT2
3.287e-02	-3.42	ENTH	smart domains	SM00273	9	1	9717	36	PICALM
3.291e-02	-3.41	ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)	protein interactions	8869	13	1	19454	50	PICALM
3.291e-02	-3.41	KCNQ4 (potassium voltage-gated channel subfamily Q member 4)	protein interactions	9132	13	1	19454	50	KCNQ3
3.291e-02	-3.41	PCAT1 (prostate cancer associated transcript 1)	protein interactions	100750225	13	1	19454	50	NAV3
3.291e-02	-3.41	MYO16 (myosin XVI)	protein interactions	23026	13	1	19454	50	ARHGAP26
3.291e-02	-3.41	MRNIP (MRN complex interacting protein)	protein interactions	51149	13	1	19454	50	ANKRD44
3.291e-02	-3.41	MSC (musculin)	protein interactions	9242	13	1	19454	50	TCF12
3.291e-02	-3.41	Rbm47 (RNA binding motif protein 47)	protein interactions	245945	13	1	19454	50	QKI
3.291e-02	-3.41	IBSP (integrin binding sialoprotein)	protein interactions	3381	13	1	19454	50	PLXDC2
3.291e-02	-3.41	ZNF284 (zinc finger protein 284)	protein interactions	342909	13	1	19454	50	SORL1
3.291e-02	-3.41	ZNF718 (zinc finger protein 718)	protein interactions	255403	13	1	19454	50	ARHGAP24
3.291e-02	-3.41	LYSMD1 (LysM domain containing 1)	protein interactions	388695	13	1	19454	50	TCF12
3.291e-02	-3.41	CRYGC (crystallin gamma C)	protein interactions	1420	13	1	19454	50	DISC1
3.291e-02	-3.41	RTL10 (retrotransposon Gag like 10)	protein interactions	79680	13	1	19454	50	DSCAM
3.291e-02	-3.41	PLEKHH1 (pleckstrin homology, MyTH4 and FERM domain containing H1)	protein interactions	57475	13	1	19454	50	APBB1IP
3.291e-02	-3.41	KCNQ2 (potassium voltage-gated channel subfamily Q member 2)	protein interactions	3785	13	1	19454	50	KCNQ3
3.291e-02	-3.41	OGN (osteoglycin)	protein interactions	4969	13	1	19454	50	SORL1
3.296e-02	-3.41	Histone deacetylase domain	gene3d domains	3.40.800.20	11	1	14470	44	HDAC9
3.306e-02	-3.41	positive regulation of protein exit from endoplasmic reticulum	biological process	GO:0070863	13	1	18204	47	SORL1
3.306e-02	-3.41	lipid export from cell	biological process	GO:0140353	13	1	18204	47	ABCC4
3.306e-02	-3.41	negative regulation of cytosolic calcium ion concentration	biological process	GO:0051481	13	1	18204	47	SLC8A1
3.306e-02	-3.41	response to parathyroid hormone	biological process	GO:0071107	13	1	18204	47	MEF2C
3.306e-02	-3.41	regulation of triglyceride catabolic process	biological process	GO:0010896	13	1	18204	47	SORL1
3.306e-02	-3.41	negative regulation of platelet-derived growth factor receptor signaling pathway	biological process	GO:0010642	13	1	18204	47	PTPRJ
3.306e-02	-3.41	calcium ion transport into cytosol	biological process	GO:0060402	13	1	18204	47	SLC8A1
3.306e-02	-3.41	positive regulation of platelet activation	biological process	GO:0010572	13	1	18204	47	PTPRJ
3.306e-02	-3.41	diet induced thermogenesis	biological process	GO:0002024	13	1	18204	47	SORL1
3.306e-02	-3.41	regulation of protein localization to endosome	biological process	GO:1905666	13	1	18204	47	SORL1
3.306e-02	-3.41	bone-tibia-other-chondroblastoma	COSMIC cancer mutations	bone-tibia-other-chondroblastoma	98	2	16828	49	SLC9A9,ST6GALNAC3
3.307e-02	-3.41	Golgi cisterna	cellular component	GO:0031985	116	2	19108	47	ST6GAL1,SORL1
3.309e-02	-3.41	TTC17 (tetratricopeptide repeat domain 17)	protein interactions	55761	111	2	19454	50	PLXDC2,DSCAM
3.310e-02	-3.41	bladder	COSMIC cancer mutations	bladder	14112	46	16828	49	TCF12,MED13L,HDAC9,KCNQ3,QKI,SSH2,MEF2A,ARHGAP26,ELMO1,SFMBT2,SLC8A1,EPB41L2,DOCK4,ZBTB20,CHST11,GNAQ,SORL1,UBE2E2,FCHSD2,ABCC4,PTPRJ,ANKRD44,PLXDC2,DSCAM,ATP8B4,ARHGAP22,ARHGAP24,MAP4K4,ST6GAL1,MAML2,MEF2C,DIP2B,MAML3,DOCK8,TBC1D22A,ITPR2,FRMD4A,SLC9A9,HS3ST4,NAV3,ADAM28,APBB1IP,ST6GALNAC3,ZFHX3,PICALM,SYNDIG1
3.310e-02	-3.41	urinary_tract	COSMIC cancer mutations	urinary_tract	14112	46	16828	49	ADAM28,APBB1IP,NAV3,HS3ST4,SYNDIG1,PICALM,ZFHX3,ST6GALNAC3,DOCK8,MAML3,DIP2B,MEF2C,MAML2,SLC9A9,ITPR2,FRMD4A,TBC1D22A,FCHSD2,SORL1,UBE2E2,GNAQ,CHST11,MAP4K4,ST6GAL1,ARHGAP22,ARHGAP24,DSCAM,ATP8B4,ANKRD44,PTPRJ,PLXDC2,ABCC4,KCNQ3,QKI,HDAC9,MED13L,TCF12,ZBTB20,EPB41L2,DOCK4,SFMBT2,SLC8A1,MEF2A,ARHGAP26,ELMO1,SSH2
3.322e-02	-3.40	protein domain specific binding	molecular function	GO:0019904	651	5	18094	50	EPB41L2,ELMO1,TCF12,QKI,DOCK4
3.347e-02	-3.40	metal ion transmembrane transporter activity	molecular function	GO:0046873	442	4	18094	50	ITPR2,SLC9A9,KCNQ3,SLC8A1
3.386e-02	-3.39	Pancreatic secretion	KEGG pathways	ko04972	95	2	7161	22	GNAQ,ITPR2
3.386e-02	-3.39	Pancreatic secretion	KEGG pathways	hsa04972	95	2	7161	22	GNAQ,ITPR2
3.390e-02	-3.38	extrinsic component of synaptic membrane	cellular component	GO:0099243	14	1	19108	47	PICALM
3.390e-02	-3.38	phospholipid-translocating ATPase complex	cellular component	GO:1990531	14	1	19108	47	ATP8B4
3.395e-02	-3.38	gliogenesis	biological process	GO:0042063	275	3	18204	47	QKI,PTPRJ,DISC1
3.415e-02	-3.38	NGF signalling via TRKA from the plasma membrane	REACTOME pathways	R-HSA-187037	387	4	10285	33	MEF2C,MEF2A,APBB1IP,ITPR2
3.418e-02	-3.38	GYS1 (glycogen synthase 1)	protein interactions	2997	113	2	19454	50	MAP4K4,ARHGAP24
3.418e-02	-3.38	RBM6 (RNA binding motif protein 6)	protein interactions	10180	113	2	19454	50	DISC1,ARHGAP22
3.418e-02	-3.38	CARS1 (cysteinyl-tRNA synthetase 1)	protein interactions	833	113	2	19454	50	PICALM,ARHGAP24
3.423e-02	-3.37	Platelet homeostasis	REACTOME pathways	R-HSA-418346	91	2	10285	33	ITPR2,SLC8A1
3.423e-02	-3.37	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	REACTOME pathways	R-HSA-975138	91	2	10285	33	MEF2A,MEF2C
3.440e-02	-3.37	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	12	1	16828	49	GNAQ
3.440e-02	-3.37	perivascular_epithelioid_cell_tumour_(PEComa)	COSMIC cancer mutations	perivascular_epithelioid_cell_tumour_(PEComa)	12	1	16828	49	GNAQ
3.440e-02	-3.37	skin-abdomen-malignant_melanoma-nodular	COSMIC cancer mutations	skin-abdomen-malignant_melanoma-nodular	12	1	16828	49	GNAQ
3.440e-02	-3.37	central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour	COSMIC cancer mutations	central_nervous_system-cerebellum-other-rosette-forming_glioneuronal_tumour	12	1	16828	49	GNAQ
3.440e-02	-3.37	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I	12	1	16828	49	QKI
3.440e-02	-3.37	soft_tissue-blood_vessel-perivascular_epithelioid_cell_tumour_(PEComa)	COSMIC cancer mutations	soft_tissue-blood_vessel-perivascular_epithelioid_cell_tumour_(PEComa)	12	1	16828	49	GNAQ
3.440e-02	-3.37	skin-benign_melanocytic_nevus	COSMIC cancer mutations	skin-benign_melanocytic_nevus	12	1	16828	49	GNAQ
3.440e-02	-3.37	central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour	COSMIC cancer mutations	central_nervous_system-third_ventricle-other-rosette-forming_glioneuronal_tumour	12	1	16828	49	GNAQ
3.444e-02	-3.37	positive regulation of tumor necrosis factor superfamily cytokine production	biological process	GO:1903557	113	2	18204	47	PTPRJ,ZBTB20
3.449e-02	-3.37	vesicle	cellular component	GO:0031982	4141	16	19108	47	EPB41L2,PICALM,SYNDIG1,SLC9A9,DISC1,SORL1,ABCC4,SSH2,ATP8B4,FCHSD2,ITPR2,GNAQ,ARHGAP26,PTPRJ,LDLRAD4,DIP2B
3.454e-02	-3.37	CD225/Dispanin_fam	interpro domains	IPR007593	13	1	18521	50	SYNDIG1
3.454e-02	-3.37	FA	interpro domains	IPR014847	13	1	18521	50	EPB41L2
3.467e-02	-3.36	regulation of multicellular organismal development	biological process	GO:2000026	1484	8	18204	47	SORL1,DISC1,DSCAM,SLC8A1,MEF2C,QKI,SYNDIG1,DIP2B
3.470e-02	-3.36	positive regulation of gene expression	biological process	GO:0010628	1212	7	18204	47	ZBTB20,SORL1,TCF12,MEF2C,QKI,PTPRJ,MEF2A
3.474e-02	-3.36	ORF3b (ORF3b protein)	protein interactions	1489670	114	2	19454	50	ZBTB20,PTPRJ
3.475e-02	-3.36	DSCAM interactions	REACTOME pathways	R-HSA-376172	11	1	10285	33	DSCAM
3.500e-02	-3.35	Notch signaling pathway	biological process	GO:0007219	114	2	18204	47	MAML2,MAML3
3.500e-02	-3.35	regulation of circadian rhythm	biological process	GO:0042752	114	2	18204	47	GNAQ,ZFHX3
3.500e-02	-3.35	Ion_trans_dom	interpro domains	IPR005821	109	2	18521	50	ITPR2,KCNQ3
3.518e-02	-3.35	Inflammatory mediator regulation of TRP channels	KEGG pathways	ko04750	97	2	7161	22	ITPR2,GNAQ
3.518e-02	-3.35	Inflammatory mediator regulation of TRP channels	KEGG pathways	hsa04750	97	2	7161	22	GNAQ,ITPR2
3.522e-02	-3.35	CD225	pfam domains	PF04505	13	1	17795	49	SYNDIG1
3.522e-02	-3.35	Ldl_recept_b	pfam domains	PF00058	13	1	17795	49	SORL1
3.522e-02	-3.35	FA	pfam domains	PF08736	13	1	17795	49	EPB41L2
3.523e-02	-3.35	HDASUPER	prints domains	PR01270	11	1	5227	17	HDAC9
3.535e-02	-3.34	icosanoid transmembrane transporter activity	molecular function	GO:0071714	13	1	18094	50	ABCC4
3.535e-02	-3.34	calcium:monoatomic cation antiporter activity	molecular function	GO:0015368	13	1	18094	50	SLC8A1
3.535e-02	-3.34	HMG box domain binding	molecular function	GO:0071837	13	1	18094	50	TCF12
3.539e-02	-3.34	transcription regulator complex	cellular component	GO:0005667	506	4	19108	47	TCF12,ZFHX3,MEF2A,HDAC9
3.540e-02	-3.34	DACT2 (dishevelled binding antagonist of beta catenin 2)	protein interactions	168002	14	1	19454	50	ZBTB20
3.540e-02	-3.34	RSPO1 (R-spondin 1)	protein interactions	284654	14	1	19454	50	SORL1
3.540e-02	-3.34	MB (myoglobin)	protein interactions	4151	14	1	19454	50	MAML2
3.540e-02	-3.34	PLA2G12A (phospholipase A2 group XIIA)	protein interactions	81579	14	1	19454	50	MEF2C
3.540e-02	-3.34	TTLL7 (tubulin tyrosine ligase like 7)	protein interactions	79739	14	1	19454	50	MEF2A
3.540e-02	-3.34	CSF3 (colony stimulating factor 3)	protein interactions	1440	14	1	19454	50	PTPRJ
3.540e-02	-3.34	TAS2R7 (taste 2 receptor member 7)	protein interactions	50837	14	1	19454	50	GNAQ
3.540e-02	-3.34	ASCL3 (achaete-scute family bHLH transcription factor 3)	protein interactions	56676	14	1	19454	50	TCF12
3.540e-02	-3.34	PGPEP1 (pyroglutamyl-peptidase I)	protein interactions	54858	14	1	19454	50	UBE2E2
3.540e-02	-3.34	KCNQ3 (potassium voltage-gated channel subfamily Q member 3)	protein interactions	3786	14	1	19454	50	KCNQ3
3.540e-02	-3.34	PTF1A (pancreas associated transcription factor 1a)	protein interactions	256297	14	1	19454	50	TCF12
3.540e-02	-3.34	XYLT1 (xylosyltransferase 1)	protein interactions	64131	14	1	19454	50	MEF2A
3.540e-02	-3.34	HOXC6 (homeobox C6)	protein interactions	3223	14	1	19454	50	PTPRJ
3.540e-02	-3.34	RGS13 (regulator of G protein signaling 13)	protein interactions	6003	14	1	19454	50	GNAQ
3.540e-02	-3.34	Iqgap3 (IQ motif containing GTPase activating protein 3)	protein interactions	404710	14	1	19454	50	MEF2A
3.545e-02	-3.34	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm	248	3	16828	49	FRMD4A,DSCAM,SLC9A9
3.545e-02	-3.34	mast_cell_neoplasm	COSMIC cancer mutations	mast_cell_neoplasm	248	3	16828	49	DSCAM,FRMD4A,SLC9A9
3.556e-02	-3.34	neuron remodeling	biological process	GO:0016322	14	1	18204	47	KCNQ3
3.556e-02	-3.34	protein deacetylation	biological process	GO:0006476	14	1	18204	47	HDAC9
3.556e-02	-3.34	regulation of keratinocyte migration	biological process	GO:0051547	14	1	18204	47	MAP4K4
3.556e-02	-3.34	immunological synapse formation	biological process	GO:0001771	14	1	18204	47	DOCK8
3.556e-02	-3.34	positive regulation of actin nucleation	biological process	GO:0051127	14	1	18204	47	FCHSD2
3.556e-02	-3.34	relaxation of cardiac muscle	biological process	GO:0055119	14	1	18204	47	SLC8A1
3.556e-02	-3.34	dendrite self-avoidance	biological process	GO:0070593	14	1	18204	47	DSCAM
3.556e-02	-3.34	cellular response to ethanol	biological process	GO:0071361	14	1	18204	47	ITPR2
3.556e-02	-3.34	oligopeptide transport	biological process	GO:0006857	14	1	18204	47	ABCC4
3.556e-02	-3.34	cellular response to purine-containing compound	biological process	GO:0071415	14	1	18204	47	SLC8A1
3.562e-02	-3.33	Toll Like Receptor 7/8 (TLR7/8) Cascade	REACTOME pathways	R-HSA-168181	93	2	10285	33	MEF2C,MEF2A
3.562e-02	-3.33	MyD88 dependent cascade initiated on endosome	REACTOME pathways	R-HSA-975155	93	2	10285	33	MEF2C,MEF2A
3.574e-02	-3.33	human chr3q24	chromosome location	human chr3q24	19	1	26134	50	SLC9A9
3.585e-02	-3.33	Estrogen signaling pathway	KEGG pathways	ko04915	98	2	7161	22	ITPR2,GNAQ
3.585e-02	-3.33	Estrogen signaling pathway	KEGG pathways	hsa04915	98	2	7161	22	GNAQ,ITPR2
3.586e-02	-3.33	ATP6V1F (ATPase H+ transporting V1 subunit F)	protein interactions	9296	116	2	19454	50	PICALM,PLXDC2
3.627e-02	-3.32	Ion_trans	pfam domains	PF00520	109	2	17795	49	ITPR2,KCNQ3
3.629e-02	-3.32	neuron projection morphogenesis	biological process	GO:0048812	486	4	18204	47	DSCAM,PICALM,MEF2A,MAP4K4
3.642e-02	-3.31	SHTN1 (shootin 1)	protein interactions	57698	117	2	19454	50	DSCAM,ARHGAP24
3.645e-02	-3.31	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	16	16828	49	CHST11,HDAC9,GNAQ,DOCK8,SORL1,PLXDC2,ABCC4,ARHGAP26,DSCAM,ZFHX3,ATP8B4,FRMD4A,MAP4K4,DOCK4,SFMBT2,SLC8A1
3.645e-02	-3.31	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	3511	16	16828	49	DOCK4,MAP4K4,SLC8A1,SFMBT2,ARHGAP26,ATP8B4,FRMD4A,ZFHX3,DSCAM,PLXDC2,ABCC4,DOCK8,SORL1,HDAC9,GNAQ,CHST11
3.645e-02	-3.31	MIR	smart domains	SM00472	10	1	9717	36	ITPR2
3.660e-02	-3.31	negative regulation of cellular metabolic process	biological process	GO:0031324	2998	13	18204	47	PTPRJ,MEF2A,QKI,HDAC9,MEF2C,NAV3,GNAQ,SLC8A1,PICALM,ZFHX3,ZBTB20,SORL1,SFMBT2
3.661e-02	-3.31	anatomical structure formation involved in morphogenesis	biological process	GO:0048646	964	6	18204	47	MEF2A,PTPRJ,ARHGAP22,ARHGAP24,DSCAM,MEF2C
3.661e-02	-3.31	PSPC1 (paraspeckle component 1)	protein interactions	55269	489	4	19454	50	ARHGAP24,DISC1,ARHGAP26,ARHGAP22
3.669e-02	-3.31	regulation of synapse assembly	biological process	GO:0051963	117	2	18204	47	MEF2C,SYNDIG1
3.672e-02	-3.30	LDLRB	prosite domains	PS51120	13	1	12186	35	SORL1
3.685e-02	-3.30	transcription regulator activity	molecular function	GO:0140110	1937	10	18094	50	SFMBT2,MEF2A,HDAC9,ZFHX3,MEF2C,MAML3,TCF12,MAML2,ZBTB20,MED13L
3.694e-02	-3.30	cell-cell junction	cellular component	GO:0005911	513	4	19108	47	SLC8A1,ARHGAP24,FRMD4A,PTPRJ
3.699e-02	-3.30	PLCD3 (phospholipase C delta 3)	protein interactions	113026	118	2	19454	50	DISC1,ARHGAP22
3.699e-02	-3.30	KLC4 (kinesin light chain 4)	protein interactions	89953	118	2	19454	50	MEF2A,EPB41L2
3.703e-02	-3.30	Toll Like Receptor TLR1:TLR2 Cascade	REACTOME pathways	R-HSA-168179	95	2	10285	33	MEF2A,MEF2C
3.703e-02	-3.30	Toll Like Receptor TLR6:TLR2 Cascade	REACTOME pathways	R-HSA-168188	95	2	10285	33	MEF2A,MEF2C
3.703e-02	-3.30	Toll Like Receptor 2 (TLR2) Cascade	REACTOME pathways	R-HSA-181438	95	2	10285	33	MEF2A,MEF2C
3.703e-02	-3.30	MyD88:Mal cascade initiated on plasma membrane	REACTOME pathways	R-HSA-166058	95	2	10285	33	MEF2A,MEF2C
3.715e-02	-3.29	Cation/H_exchanger	interpro domains	IPR006153	14	1	18521	50	SLC9A9
3.715e-02	-3.29	P_typ_ATPase_c	interpro domains	IPR032630	14	1	18521	50	ATP8B4
3.715e-02	-3.29	P-type_ATPase_N	interpro domains	IPR032631	14	1	18521	50	ATP8B4
3.715e-02	-3.29	LDLR_classB_rpt	interpro domains	IPR000033	14	1	18521	50	SORL1
3.715e-02	-3.29	P-type_ATPase_IV	interpro domains	IPR006539	14	1	18521	50	ATP8B4
3.715e-02	-3.29	Ureohydrolase_dom_sf	interpro domains	IPR023696	14	1	18521	50	HDAC9
3.719e-02	-3.29	stomach-carcinoma-adenocarcinoma	COSMIC cancer mutations	stomach-carcinoma-adenocarcinoma	15150	48	16828	49	MAML2,MEF2C,DIP2B,MAML3,DOCK8,TBC1D22A,ITPR2,FRMD4A,SLC9A9,HS3ST4,NAV3,ADAM28,APBB1IP,ST6GALNAC3,ZFHX3,PICALM,SYNDIG1,TCF12,MED13L,HDAC9,KCNQ3,QKI,SSH2,MEF2A,ELMO1,ARHGAP26,SFMBT2,SLC8A1,EPB41L2,DOCK4,ZBTB20,ZFAND3,CHST11,GNAQ,SORL1,DISC1,UBE2E2,FCHSD2,ABCC4,ANKRD44,PTPRJ,PLXDC2,DSCAM,ATP8B4,ARHGAP22,ARHGAP24,MAP4K4,ST6GAL1
3.721e-02	-3.29	skin-shoulder-malignant_melanoma-nodular	COSMIC cancer mutations	skin-shoulder-malignant_melanoma-nodular	13	1	16828	49	GNAQ
3.721e-02	-3.29	skin-scalp-malignant_melanoma-nodular	COSMIC cancer mutations	skin-scalp-malignant_melanoma-nodular	13	1	16828	49	GNAQ
3.721e-02	-3.29	skin-malignant_melanoma-lentigo_maligna	COSMIC cancer mutations	skin-malignant_melanoma-lentigo_maligna	13	1	16828	49	GNAQ
3.721e-02	-3.29	autonomic_ganglia-adrenal_gland-paraganglioma-benign	COSMIC cancer mutations	autonomic_ganglia-adrenal_gland-paraganglioma-benign	13	1	16828	49	DIP2B
3.721e-02	-3.29	stomach-adenoma	COSMIC cancer mutations	stomach-adenoma	13	1	16828	49	GNAQ
3.721e-02	-3.29	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I	13	1	16828	49	QKI
3.721e-02	-3.29	anus	COSMIC cancer mutations	anus	13	1	16828	49	GNAQ
3.747e-02	-3.28	plasma membrane bounded cell projection morphogenesis	biological process	GO:0120039	491	4	18204	47	PICALM,DSCAM,MEF2A,MAP4K4
3.756e-02	-3.28	HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1)	protein interactions	3113	119	2	19454	50	CHST11,SORL1
3.756e-02	-3.28	H2BC18 (H2B clustered histone 18)	protein interactions	440689	119	2	19454	50	ARHGAP24,FRMD4A
3.788e-02	-3.27	HOXA11 (homeobox A11)	protein interactions	3207	15	1	19454	50	PICALM
3.788e-02	-3.27	TESPA1 (thymocyte expressed, positive selection associated 1)	protein interactions	9840	15	1	19454	50	ITPR2
3.788e-02	-3.27	ZNF616 (zinc finger protein 616)	protein interactions	90317	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	ASIP (agouti signaling protein)	protein interactions	434	15	1	19454	50	SORL1
3.788e-02	-3.27	ZNF816 (zinc finger protein 816)	protein interactions	125893	15	1	19454	50	SORL1
3.788e-02	-3.27	DEFB123 (defensin beta 123)	protein interactions	245936	15	1	19454	50	SORL1
3.788e-02	-3.27	NYAP2 (neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2)	protein interactions	57624	15	1	19454	50	ARHGAP26
3.788e-02	-3.27	TIAM2 (TIAM Rac1 associated GEF 2)	protein interactions	26230	15	1	19454	50	DISC1
3.788e-02	-3.27	ZNF714 (zinc finger protein 714)	protein interactions	148206	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1)	protein interactions	953	15	1	19454	50	ANKRD44
3.788e-02	-3.27	ZNF813 (zinc finger protein 813)	protein interactions	126017	15	1	19454	50	ARHGAP24
3.788e-02	-3.27	HOPX (HOP homeobox)	protein interactions	84525	15	1	19454	50	TCF12
3.788e-02	-3.27	ADRA1B (adrenoceptor alpha 1B)	protein interactions	147	15	1	19454	50	GNAQ
3.788e-02	-3.27	ASCL4 (achaete-scute family bHLH transcription factor 4)	protein interactions	121549	15	1	19454	50	TCF12
3.788e-02	-3.27	GRM7 (glutamate metabotropic receptor 7)	protein interactions	2917	15	1	19454	50	GNAQ
3.788e-02	-3.27	TMEM255B (transmembrane protein 255B)	protein interactions	348013	15	1	19454	50	PLXDC2
3.788e-02	-3.27	CDHR5 (cadherin related family member 5)	protein interactions	53841	15	1	19454	50	SORL1
3.788e-02	-3.27	FERD3L (Fer3 like bHLH transcription factor)	protein interactions	222894	15	1	19454	50	TCF12
3.788e-02	-3.27	PRSS22 (serine protease 22)	protein interactions	64063	15	1	19454	50	SORL1
3.788e-02	-3.27	Retrograde endocannabinoid signaling	KEGG pathways	hsa04723	101	2	7161	22	GNAQ,ITPR2
3.788e-02	-3.27	Retrograde endocannabinoid signaling	KEGG pathways	ko04723	101	2	7161	22	GNAQ,ITPR2
3.788e-02	-3.27	PhoLip_ATPase_C	pfam domains	PF16212	14	1	17795	49	ATP8B4
3.788e-02	-3.27	PhoLip_ATPase_N	pfam domains	PF16209	14	1	17795	49	ATP8B4
3.788e-02	-3.27	Na_H_Exchanger	pfam domains	PF00999	14	1	17795	49	SLC9A9
3.801e-02	-3.27	ABC-type xenobiotic transporter activity	molecular function	GO:0008559	14	1	18094	50	ABCC4
3.801e-02	-3.27	potassium:proton antiporter activity	molecular function	GO:0015386	14	1	18094	50	SLC9A9
3.801e-02	-3.27	platelet-derived growth factor receptor binding	molecular function	GO:0005161	14	1	18094	50	PTPRJ
3.805e-02	-3.27	positive regulation of protein acetylation	biological process	GO:1901985	15	1	18204	47	DIP2B
3.805e-02	-3.27	glycosylceramide metabolic process	biological process	GO:0006677	15	1	18204	47	ST6GALNAC3
3.805e-02	-3.27	response to caffeine	biological process	GO:0031000	15	1	18204	47	SLC8A1
3.805e-02	-3.27	pyramidal neuron differentiation	biological process	GO:0021859	15	1	18204	47	DISC1
3.805e-02	-3.27	endosome to plasma membrane protein transport	biological process	GO:0099638	15	1	18204	47	SORL1
3.814e-02	-3.27	ZDHHC15 (zinc finger DHHC-type palmitoyltransferase 15)	protein interactions	158866	120	2	19454	50	DOCK4,MED13L
3.814e-02	-3.27	RUNX1T1 (RUNX1 partner transcriptional co-repressor 1)	protein interactions	862	120	2	19454	50	UBE2E2,TCF12
3.814e-02	-3.27	MED24 (mediator complex subunit 24)	protein interactions	9862	120	2	19454	50	QKI,MED13L
3.814e-02	-3.27	FFAR2 (free fatty acid receptor 2)	protein interactions	2867	120	2	19454	50	SYNDIG1,GNAQ
3.823e-02	-3.26	cell activation	biological process	GO:0001775	725	5	18204	47	DOCK8,MEF2C,HDAC9,PTPRJ,APBB1IP
3.824e-02	-3.26	SH3	smart domains	SM00326	202	3	9717	36	DOCK4,FCHSD2,ARHGAP26
3.846e-02	-3.26	Toll Like Receptor 9 (TLR9) Cascade	REACTOME pathways	R-HSA-168138	97	2	10285	33	MEF2A,MEF2C
3.857e-02	-3.26	Glucagon signaling pathway	KEGG pathways	hsa04922	102	2	7161	22	ITPR2,GNAQ
3.857e-02	-3.26	Glucagon signaling pathway	KEGG pathways	ko04922	102	2	7161	22	ITPR2,GNAQ
3.865e-02	-3.25	T cell receptor complex	cellular component	GO:0042101	16	1	19108	47	APBB1IP
3.865e-02	-3.25	node of Ranvier	cellular component	GO:0033268	16	1	19108	47	KCNQ3
3.866e-02	-3.25	cell projection morphogenesis	biological process	GO:0048858	496	4	18204	47	MEF2A,DSCAM,PICALM,MAP4K4
3.872e-02	-3.25	MED15 (mediator complex subunit 15)	protein interactions	51586	121	2	19454	50	MED13L,QKI
3.874e-02	-3.25	TRIM27 (tripartite motif containing 27)	protein interactions	5987	498	4	19454	50	ARHGAP22,ZFHX3,DISC1,UBE2E2
3.900e-02	-3.24	regulation of epithelial to mesenchymal transition	biological process	GO:0010717	121	2	18204	47	QKI,LDLRAD4
3.930e-02	-3.24	H2BC1 (H2B clustered histone 1)	protein interactions	255626	122	2	19454	50	MEF2A,ARHGAP24
3.943e-02	-3.23	human chr13q32.1	chromosome location	human chr13q32.1	21	1	26134	50	ABCC4
3.946e-02	-3.23	negative regulation of protein phosphorylation	biological process	GO:0001933	292	3	18204	47	SLC8A1,PTPRJ,GNAQ
3.970e-02	-3.23	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	COSMIC cancer mutations	bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	649	5	16828	49	EPB41L2,PTPRJ,ABCC4,FCHSD2,QKI
3.975e-02	-3.23	Sialyl_trans	interpro domains	IPR012163	15	1	18521	50	ST6GAL1
3.975e-02	-3.23	CNH_dom	interpro domains	IPR001180	15	1	18521	50	MAP4K4
3.991e-02	-3.22	Toll Like Receptor 3 (TLR3) Cascade	REACTOME pathways	R-HSA-168164	99	2	10285	33	MEF2A,MEF2C
3.991e-02	-3.22	TRIF-mediated TLR3/TLR4 signaling	REACTOME pathways	R-HSA-937061	99	2	10285	33	MEF2A,MEF2C
3.991e-02	-3.22	MyD88-independent TLR3/TLR4 cascade	REACTOME pathways	R-HSA-166166	99	2	10285	33	MEF2C,MEF2A
4.002e-02	-3.22	conjunctiva	COSMIC cancer mutations	conjunctiva	14	1	16828	49	GNAQ
4.035e-02	-3.21	APC2 (APC regulator of WNT signaling pathway 2)	protein interactions	10297	16	1	19454	50	DSCAM
4.035e-02	-3.21	AKAP6 (A-kinase anchoring protein 6)	protein interactions	9472	16	1	19454	50	DISC1
4.035e-02	-3.21	CDC42EP2 (CDC42 effector protein 2)	protein interactions	10435	16	1	19454	50	ARHGAP26
4.035e-02	-3.21	HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2)	protein interactions	9956	16	1	19454	50	HS3ST4
4.035e-02	-3.21	GMPR2 (guanosine monophosphate reductase 2)	protein interactions	51292	16	1	19454	50	ARHGAP24
4.035e-02	-3.21	CDH12 (cadherin 12)	protein interactions	1010	16	1	19454	50	FRMD4A
4.035e-02	-3.21	FIGLA (folliculogenesis specific bHLH transcription factor)	protein interactions	344018	16	1	19454	50	TCF12
4.035e-02	-3.21	RGS16 (regulator of G protein signaling 16)	protein interactions	6004	16	1	19454	50	GNAQ
4.035e-02	-3.21	Sumo3 (small ubiquitin-like modifier 3)	protein interactions	20610	16	1	19454	50	ITPR2
4.035e-02	-3.21	NEUROG1 (neurogenin 1)	protein interactions	4762	16	1	19454	50	TCF12
4.045e-02	-3.21	PTK2 (protein tyrosine kinase 2)	protein interactions	5747	296	3	19454	50	APBB1IP,ARHGAP26,MAP4K4
4.045e-02	-3.21	CSNK1E (casein kinase 1 epsilon)	protein interactions	1454	296	3	19454	50	ARHGAP26,LDLRAD4,ARHGAP22
4.053e-02	-3.21	CNH	pfam domains	PF00780	15	1	17795	49	MAP4K4
4.054e-02	-3.21	heparan sulfate proteoglycan metabolic process	biological process	GO:0030201	16	1	18204	47	HS3ST4
4.054e-02	-3.21	regulation of axon extension involved in axon guidance	biological process	GO:0048841	16	1	18204	47	DSCAM
4.054e-02	-3.21	xenobiotic transmembrane transport	biological process	GO:0006855	16	1	18204	47	ABCC4
4.054e-02	-3.21	regulation of cell communication by electrical coupling	biological process	GO:0010649	16	1	18204	47	SLC8A1
4.054e-02	-3.21	regulation of adipose tissue development	biological process	GO:1904177	16	1	18204	47	SORL1
4.054e-02	-3.21	wound healing, spreading of epidermal cells	biological process	GO:0035313	16	1	18204	47	ARHGAP24
4.054e-02	-3.21	vascular associated smooth muscle contraction	biological process	GO:0014829	16	1	18204	47	SLC8A1
4.054e-02	-3.21	prostaglandin transport	biological process	GO:0015732	16	1	18204	47	ABCC4
4.067e-02	-3.20	heparan sulfate sulfotransferase activity	molecular function	GO:0034483	15	1	18094	50	HS3ST4
4.067e-02	-3.20	low-density lipoprotein particle receptor activity	molecular function	GO:0005041	15	1	18094	50	SORL1
4.067e-02	-3.20	1-phosphatidylinositol binding	molecular function	GO:0005545	15	1	18094	50	PICALM
4.067e-02	-3.20	efflux transmembrane transporter activity	molecular function	GO:0015562	15	1	18094	50	ABCC4
4.068e-02	-3.20	phosphatidylinositol binding	molecular function	GO:0035091	276	3	18094	50	ITPR2,PICALM,FCHSD2
4.077e-02	-3.20	regulation of ossification	biological process	GO:0030278	124	2	18204	47	SLC8A1,MEF2C
4.079e-02	-3.20	SP7 (Sp7 transcription factor)	protein interactions	121340	297	3	19454	50	QKI,SORL1,MEF2A
4.079e-02	-3.20	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	COSMIC cancer mutations	urinary_tract-bladder-carcinoma-transitional_cell_carcinoma	6040	24	16828	49	CHST11,NAV3,GNAQ,SORL1,ABCC4,PLXDC2,ANKRD44,PTPRJ,ATP8B4,DSCAM,ZFHX3,ST6GAL1,TCF12,MED13L,DIP2B,DOCK8,TBC1D22A,FRMD4A,ITPR2,ELMO1,ARHGAP26,SLC8A1,EPB41L2,ZBTB20
4.087e-02	-3.20	monoatomic cation homeostasis	biological process	GO:0055080	505	4	18204	47	SLC9A9,DISC1,PICALM,SLC8A1
4.087e-02	-3.20	Cell-type Dependent Selectivity of CCK2R Signaling	WikiPathways	WP3679	13	1	5310	17	GNAQ
4.094e-02	-3.20	Sodium/Calcium exchangers	REACTOME pathways	R-HSA-425561	13	1	10285	33	SLC8A1
4.094e-02	-3.20	CLEC7A (Dectin-1) induces NFAT activation	REACTOME pathways	R-HSA-5607763	13	1	10285	33	ITPR2
4.095e-02	-3.20	transitional_cell_carcinoma	COSMIC cancer mutations	transitional_cell_carcinoma	6042	24	16828	49	MED13L,TCF12,DOCK8,DIP2B,ELMO1,ARHGAP26,ITPR2,FRMD4A,TBC1D22A,ZBTB20,EPB41L2,SLC8A1,NAV3,CHST11,SORL1,GNAQ,DSCAM,ZFHX3,ATP8B4,PTPRJ,ANKRD44,PLXDC2,ABCC4,ST6GAL1
4.106e-02	-3.19	GPRASP2 (G protein-coupled receptor associated sorting protein 2)	protein interactions	114928	125	2	19454	50	DISC1,FCHSD2
4.127e-02	-3.19	human chr3q13.31	chromosome location	human chr3q13.31	22	1	26134	50	ZBTB20
4.137e-02	-3.19	actomyosin structure organization	biological process	GO:0031032	125	2	18204	47	EPB41L2,MEF2A
4.145e-02	-3.18	skin-acral-malignant_melanoma	COSMIC cancer mutations	skin-acral-malignant_melanoma	264	3	16828	49	ABCC4,ARHGAP22,GNAQ
4.145e-02	-3.18	rib	COSMIC cancer mutations	rib	264	3	16828	49	MAML3,CHST11,SORL1
4.147e-02	-3.18	AMOT (angiomotin)	protein interactions	154796	299	3	19454	50	MAP4K4,ARHGAP24,DISC1
4.151e-02	-3.18	DISINTEGRIN	prints domains	PR00289	13	1	5227	17	ADAM28
4.162e-02	-3.18	circulatory system process	biological process	GO:0003013	508	4	18204	47	DOCK4,SLC8A1,ABCC4,PTPRJ
4.166e-02	-3.18	RNF115 (ring finger protein 115)	protein interactions	27246	126	2	19454	50	DOCK4,UBE2E2
4.166e-02	-3.18	VPS18 (VPS18 core subunit of CORVET and HOPS complexes)	protein interactions	57617	126	2	19454	50	LDLRAD4,DISC1
4.184e-02	-3.17	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	COSMIC cancer mutations	haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma	265	3	16828	49	ZFHX3,ITPR2,MEF2C
4.196e-02	-3.17	ductolobular_carcinoma	COSMIC cancer mutations	ductolobular_carcinoma	1619	9	16828	49	HS3ST4,ATP8B4,MEF2C,NAV3,GNAQ,SFMBT2,QKI,SORL1,KCNQ3
4.196e-02	-3.17	breast-carcinoma-ductolobular_carcinoma	COSMIC cancer mutations	breast-carcinoma-ductolobular_carcinoma	1619	9	16828	49	HS3ST4,ATP8B4,MEF2C,NAV3,GNAQ,SFMBT2,QKI,SORL1,KCNQ3
4.196e-02	-3.17	breast-carcinoma-ER-PR-positive_carcinoma	COSMIC cancer mutations	breast-carcinoma-ER-PR-positive_carcinoma	1881	10	16828	49	MEF2A,ARHGAP26,ELMO1,MEF2C,MAML2,TCF12,MAP4K4,MAML3,GNAQ,PICALM
4.196e-02	-3.17	ER-PR-positive_carcinoma	COSMIC cancer mutations	ER-PR-positive_carcinoma	1881	10	16828	49	MAML3,MAP4K4,PICALM,GNAQ,MAML2,TCF12,ELMO1,ARHGAP26,MEF2A,MEF2C
4.197e-02	-3.17	response to ethanol	biological process	GO:0045471	126	2	18204	47	ITPR2,ST6GAL1
4.212e-02	-3.17	DNA-binding transcription factor binding	molecular function	GO:0140297	476	4	18094	50	TCF12,MEF2A,HDAC9,MEF2C
4.220e-02	-3.17	regulation of epithelial cell migration	biological process	GO:0010632	300	3	18204	47	HDAC9,MEF2C,MAP4K4
4.223e-02	-3.16	large_intestine-adenoma	COSMIC cancer mutations	large_intestine-adenoma	266	3	16828	49	TCF12,KCNQ3,NAV3
4.225e-02	-3.16	CNH	prosite domains	PS50219	15	1	12186	35	MAP4K4
4.235e-02	-3.16	Gprotein_alpha_su	interpro domains	IPR001019	16	1	18521	50	GNAQ
4.235e-02	-3.16	GproteinA_insert	interpro domains	IPR011025	16	1	18521	50	GNAQ
4.235e-02	-3.16	Disintegrin_CS	interpro domains	IPR018358	16	1	18521	50	ADAM28
4.235e-02	-3.16	Ez/rad/moesin-like	interpro domains	IPR000798	16	1	18521	50	EPB41L2
4.236e-02	-3.16	regulation of intracellular signal transduction	biological process	GO:1902531	1832	9	18204	47	MAP4K4,LDLRAD4,PICALM,ARHGAP22,MEF2C,DOCK8,PTPRJ,ARHGAP26,ARHGAP24
4.282e-02	-3.15	hypothalamus	COSMIC cancer mutations	hypothalamus	15	1	16828	49	QKI
4.282e-02	-3.15	rosette-forming_glioneuronal_tumour	COSMIC cancer mutations	rosette-forming_glioneuronal_tumour	15	1	16828	49	GNAQ
4.282e-02	-3.15	central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour	COSMIC cancer mutations	central_nervous_system-fourth_ventricle-other-rosette-forming_glioneuronal_tumour	15	1	16828	49	GNAQ
4.282e-02	-3.15	Pef1 (penta-EF hand domain containing 1)	protein interactions	67898	17	1	19454	50	QKI
4.282e-02	-3.15	OLFM1 (olfactomedin 1)	protein interactions	10439	17	1	19454	50	DISC1
4.282e-02	-3.15	ZDHHC22 (zinc finger DHHC-type palmitoyltransferase 22)	protein interactions	283576	17	1	19454	50	LDLRAD4
4.282e-02	-3.15	Abr (active BCR-related gene)	protein interactions	109934	17	1	19454	50	DOCK4
4.282e-02	-3.15	CPPED1 (calcineurin like phosphoesterase domain containing 1)	protein interactions	55313	17	1	19454	50	PICALM
4.282e-02	-3.15	ARL4A (ADP ribosylation factor like GTPase 4A)	protein interactions	10124	17	1	19454	50	ELMO1
4.282e-02	-3.15	DPRX (divergent-paired related homeobox)	protein interactions	503834	17	1	19454	50	ZFHX3
4.282e-02	-3.15	ZNF557 (zinc finger protein 557)	protein interactions	79230	17	1	19454	50	ARHGAP24
4.290e-02	-3.15	organelle	cellular component	GO:0043226	14500	41	19108	47	TCF12,PTPRJ,MAML2,MEF2A,MED13L,SSH2,ST6GAL1,ATP8B4,ZFHX3,CHST11,DISC1,SFMBT2,DOCK4,ZBTB20,EPB41L2,PICALM,HS3ST4,SLC9A9,GNAQ,ARHGAP26,UBE2E2,LDLRAD4,DIP2B,APBB1IP,FCHSD2,QKI,ADAM28,FRMD4A,ITPR2,ST6GALNAC3,MAML3,SORL1,ABCC4,NAV3,SLC8A1,MEF2C,SYNDIG1,ARHGAP22,HDAC9,ARHGAP24,KCNQ3
4.292e-02	-3.15	postsynaptic density	cellular component	GO:0014069	317	3	19108	47	SYNDIG1,SLC8A1,DISC1
4.297e-02	-3.15	RAC1 (Rac family small GTPase 1)	protein interactions	5879	1005	6	19454	50	PTPRJ,DOCK8,MAP4K4,DOCK4,ARHGAP22,PICALM
4.301e-02	-3.15	regulation of inclusion body assembly	biological process	GO:0090083	17	1	18204	47	SORL1
4.301e-02	-3.15	cell communication by electrical coupling involved in cardiac conduction	biological process	GO:0086064	17	1	18204	47	SLC8A1
4.301e-02	-3.15	specification of animal organ identity	biological process	GO:0010092	17	1	18204	47	MEF2C
4.301e-02	-3.15	negative regulation of triglyceride metabolic process	biological process	GO:0090209	17	1	18204	47	SORL1
4.301e-02	-3.15	membrane depolarization during cardiac muscle cell action potential	biological process	GO:0086012	17	1	18204	47	SLC8A1
4.301e-02	-3.15	ganglioside biosynthetic process	biological process	GO:0001574	17	1	18204	47	ST6GALNAC3
4.301e-02	-3.15	muscle cell fate commitment	biological process	GO:0042693	17	1	18204	47	MEF2C
4.301e-02	-3.15	microvillus assembly	biological process	GO:0030033	17	1	18204	47	MAP4K4
4.302e-02	-3.15	acral	COSMIC cancer mutations	acral	268	3	16828	49	ARHGAP22,GNAQ,ABCC4
4.317e-02	-3.14	negative regulation of transforming growth factor beta receptor signaling pathway	biological process	GO:0030512	128	2	18204	47	LDLRAD4,CHST11
4.318e-02	-3.14	G-alpha	pfam domains	PF00503	16	1	17795	49	GNAQ
4.321e-02	-3.14	C3orf52 (chromosome 3 open reading frame 52)	protein interactions	79669	304	3	19454	50	ITPR2,ST6GALNAC3,ABCC4
4.329e-02	-3.14	small GTPase binding	molecular function	GO:0031267	283	3	18094	50	SORL1,DOCK4,PICALM
4.333e-02	-3.14	sodium:proton antiporter activity	molecular function	GO:0015385	16	1	18094	50	SLC9A9
4.338e-02	-3.14	clathrin coat of coated pit	cellular component	GO:0030132	18	1	19108	47	PICALM
4.340e-02	-3.14	monoatomic ion homeostasis	biological process	GO:0050801	515	4	18204	47	DISC1,SLC9A9,SLC8A1,PICALM
4.346e-02	-3.14	protein binding	molecular function	GO:0005515	13983	44	18094	50	KCNQ3,ZFAND3,ADAM28,ARHGAP22,MEF2C,GNAQ,TBC1D22A,ITPR2,ABCC4,ELMO1,MEF2A,LDLRAD4,ANKRD44,QKI,MAML2,SFMBT2,DISC1,ST6GAL1,SLC9A9,PLXDC2,PICALM,TCF12,ARHGAP24,DOCK4,PTPRJ,FCHSD2,DOCK8,ATP8B4,MAP4K4,ST6GALNAC3,ZFHX3,SSH2,SLC8A1,DIP2B,ARHGAP26,SORL1,EPB41L2,HDAC9,MAML3,NAV3,SYNDIG1,DSCAM,UBE2E2,APBB1IP
4.348e-02	-3.14	protein kinase binding	molecular function	GO:0019901	701	5	18094	50	HDAC9,DSCAM,DOCK4,MEF2A,PTPRJ
4.352e-02	-3.13	skin-chest-malignant_melanoma	COSMIC cancer mutations	skin-chest-malignant_melanoma	114	2	16828	49	PTPRJ,GNAQ
4.402e-02	-3.12	Reduction of cytosolic Ca++ levels	REACTOME pathways	R-HSA-418359	14	1	10285	33	SLC8A1
4.407e-02	-3.12	ARHGEF1 (Rho guanine nucleotide exchange factor 1)	protein interactions	9138	130	2	19454	50	DOCK4,GNAQ
4.407e-02	-3.12	SORL1 (sortilin related receptor 1)	protein interactions	6653	130	2	19454	50	SORL1,DISC1
4.440e-02	-3.11	lymphocyte proliferation	biological process	GO:0046651	130	2	18204	47	MEF2C,DOCK8
4.440e-02	-3.11	B cell differentiation	biological process	GO:0030183	130	2	18204	47	HDAC9,PTPRJ
4.440e-02	-3.11	detection of external stimulus	biological process	GO:0009581	130	2	18204	47	GNAQ,DISC1
4.468e-02	-3.11	LGALS7 (galectin 7)	protein interactions	3963	131	2	19454	50	PTPRJ,DOCK8
4.492e-02	-3.10	Signal Transduction	REACTOME pathways	R-HSA-162582	2547	13	10285	33	GNAQ,ARHGAP26,PTPRJ,MEF2C,ARHGAP24,HDAC9,APBB1IP,ELMO1,MAML3,MEF2A,ARHGAP22,ITPR2,MAML2
4.494e-02	-3.10	human chr3p24.3	chromosome location	human chr3p24.3	24	1	26134	50	UBE2E2
4.494e-02	-3.10	human chr8q24.22	chromosome location	human chr8q24.22	24	1	26134	50	KCNQ3
4.494e-02	-3.10	human chr11q24.1	chromosome location	human chr11q24.1	24	1	26134	50	SORL1
4.499e-02	-3.10	ITCH (itchy E3 ubiquitin protein ligase)	protein interactions	83737	309	3	19454	50	UBE2E2,DISC1,LDLRAD4
4.500e-02	-3.10	DISINTEGRIN_1	prosite domains	PS00427	16	1	12186	35	ADAM28
4.500e-02	-3.10	G_ALPHA	prosite domains	PS51882	16	1	12186	35	GNAQ
4.508e-02	-3.10	vesicle-mediated transport	biological process	GO:0016192	1283	7	18204	47	ELMO1,ABCC4,SYNDIG1,KCNQ3,PICALM,FCHSD2,SORL1
4.515e-02	-3.10	Glycosphingolipid biosynthesis - ganglio series	KEGG pathways	hsa00604	15	1	7161	22	ST6GALNAC3
4.515e-02	-3.10	Glycosphingolipid biosynthesis - ganglio series	KEGG pathways	ko00604	15	1	7161	22	ST6GALNAC3
4.524e-02	-3.10	pancreatic_intraepithelial_neoplasia_(PanIN)	COSMIC cancer mutations	pancreatic_intraepithelial_neoplasia_(PanIN)	673	5	16828	49	NAV3,MAML3,DOCK4,MAP4K4,ABCC4
4.524e-02	-3.10	pancreas-pancreatic_intraepithelial_neoplasia_(PanIN)	COSMIC cancer mutations	pancreas-pancreatic_intraepithelial_neoplasia_(PanIN)	673	5	16828	49	ABCC4,MAML3,MAP4K4,DOCK4,NAV3
4.529e-02	-3.09	ZNF224 (zinc finger protein 224)	protein interactions	7767	18	1	19454	50	SORL1
4.529e-02	-3.09	ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)	protein interactions	9744	18	1	19454	50	FCHSD2
4.529e-02	-3.09	AK9 (adenylate kinase 9)	protein interactions	221264	18	1	19454	50	ARHGAP24
4.529e-02	-3.09	CCN6 (cellular communication network factor 6)	protein interactions	8838	18	1	19454	50	SORL1
4.529e-02	-3.09	CYP17A1 (cytochrome P450 family 17 subfamily A member 1)	protein interactions	1586	18	1	19454	50	PTPRJ
4.529e-02	-3.09	ZNF100 (zinc finger protein 100)	protein interactions	163227	18	1	19454	50	ARHGAP24
4.529e-02	-3.09	CXXC5 (CXXC finger protein 5)	protein interactions	51523	18	1	19454	50	DSCAM
4.529e-02	-3.09	SRR (serine racemase)	protein interactions	63826	18	1	19454	50	DISC1
4.529e-02	-3.09	RILPL1 (Rab interacting lysosomal protein like 1)	protein interactions	353116	18	1	19454	50	DSCAM
4.529e-02	-3.09	ADO (2-aminoethanethiol dioxygenase)	protein interactions	84890	18	1	19454	50	DISC1
4.529e-02	-3.09	FAM25A (family with sequence similarity 25 member A)	protein interactions	643161	18	1	19454	50	ZFAND3
4.529e-02	-3.09	SPARCL1 (SPARC like 1)	protein interactions	8404	18	1	19454	50	DISC1
4.549e-02	-3.09	clathrin coat assembly	biological process	GO:0048268	18	1	18204	47	PICALM
4.549e-02	-3.09	negative regulation of vascular permeability	biological process	GO:0043116	18	1	18204	47	PTPRJ
4.549e-02	-3.09	positive regulation of cardiocyte differentiation	biological process	GO:1905209	18	1	18204	47	MEF2C
4.549e-02	-3.09	cardiac myofibril assembly	biological process	GO:0055003	18	1	18204	47	MEF2A
4.549e-02	-3.09	heart formation	biological process	GO:0060914	18	1	18204	47	MEF2C
4.561e-02	-3.09	eye-uveal_tract-malignant_melanoma-epithelioid	COSMIC cancer mutations	eye-uveal_tract-malignant_melanoma-epithelioid	16	1	16828	49	GNAQ
4.561e-02	-3.09	neurocristic_hamartoma	COSMIC cancer mutations	neurocristic_hamartoma	16	1	16828	49	GNAQ
4.561e-02	-3.09	pineal_gland	COSMIC cancer mutations	pineal_gland	16	1	16828	49	GNAQ
4.561e-02	-3.09	myxoid	COSMIC cancer mutations	myxoid	16	1	16828	49	TCF12
4.561e-02	-3.09	central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_II	COSMIC cancer mutations	central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_II	16	1	16828	49	GNAQ
4.561e-02	-3.09	skin-other-neurocristic_hamartoma	COSMIC cancer mutations	skin-other-neurocristic_hamartoma	16	1	16828	49	GNAQ
4.561e-02	-3.09	flank	COSMIC cancer mutations	flank	16	1	16828	49	GNAQ
4.563e-02	-3.09	negative regulation of neurogenesis	biological process	GO:0050768	132	2	18204	47	SORL1,DIP2B
4.569e-02	-3.09	Serotonergic synapse	KEGG pathways	hsa04726	112	2	7161	22	GNAQ,ITPR2
4.574e-02	-3.08	phospholipid binding	molecular function	GO:0005543	489	4	18094	50	FCHSD2,ARHGAP26,PICALM,ITPR2
4.591e-02	-3.08	H2BC26 (H2B clustered histone 26)	protein interactions	128312	133	2	19454	50	ARHGAP24,MAP4K4
4.591e-02	-3.08	CBS (cystathionine beta-synthase)	protein interactions	875	133	2	19454	50	ARHGAP24,ARHGAP26
4.593e-02	-3.08	Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME pathways	R-HSA-425393	107	2	10285	33	SLC9A9,SLC8A1
4.597e-02	-3.08	low-density lipoprotein particle binding	molecular function	GO:0030169	17	1	18094	50	SORL1
4.606e-02	-3.08	extraskeletal	COSMIC cancer mutations	extraskeletal	903	6	16828	49	TCF12,GNAQ,ANKRD44,ZFHX3,ITPR2,ADAM28
4.607e-02	-3.08	ACTN1 (actinin alpha 1)	protein interactions	87	312	3	19454	50	ARHGAP24,DISC1,DSCAM
4.625e-02	-3.07	detection of abiotic stimulus	biological process	GO:0009582	133	2	18204	47	DISC1,GNAQ
4.625e-02	-3.07	regulation of sequestering of calcium ion	biological process	GO:0051282	133	2	18204	47	ITPR2,SLC8A1
4.635e-02	-3.07	response to nitrogen compound	biological process	GO:1901698	1021	6	18204	47	HDAC9,ITPR2,SLC8A1,GNAQ,TCF12,MEF2C
4.643e-02	-3.07	inorganic molecular entity transmembrane transporter activity	molecular function	GO:0015318	714	5	18094	50	ABCC4,ITPR2,SLC9A9,KCNQ3,SLC8A1
4.644e-02	-3.07	HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor)	protein interactions	55662	313	3	19454	50	MAP4K4,ANKRD44,TCF12
4.677e-02	-3.06	protein tyrosine kinase binding	molecular function	GO:1990782	125	2	18094	50	DSCAM,DOCK4
4.677e-02	-3.06	human chr7q31.1	chromosome location	human chr7q31.1	25	1	26134	50	DOCK4
4.680e-02	-3.06	ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2)	protein interactions	10425	314	3	19454	50	DISC1,UBE2E2,DSCAM
4.686e-02	-3.06	negative regulation of phosphorylation	biological process	GO:0042326	313	3	18204	47	PTPRJ,SLC8A1,GNAQ
4.688e-02	-3.06	mononuclear cell proliferation	biological process	GO:0032943	134	2	18204	47	MEF2C,DOCK8
4.688e-02	-3.06	regulation of actin filament polymerization	biological process	GO:0030833	134	2	18204	47	FCHSD2,SSH2
4.709e-02	-3.06	N-Glycan antennae elongation	REACTOME pathways	R-HSA-975577	15	1	10285	33	ST6GAL1
4.714e-02	-3.05	FA	smart domains	SM01195	13	1	9717	36	EPB41L2
4.716e-02	-3.05	HDAC7 (histone deacetylase 7)	protein interactions	51564	135	2	19454	50	MEF2A,MEF2C
4.718e-02	-3.05	Glutamatergic synapse	KEGG pathways	hsa04724	114	2	7161	22	GNAQ,ITPR2
4.718e-02	-3.05	Glutamatergic synapse	KEGG pathways	ko04724	114	2	7161	22	ITPR2,GNAQ
4.722e-02	-3.05	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	COSMIC cancer mutations	central_nervous_system-brain-glioma-astrocytoma_Grade_IV	15813	49	16828	49	CHST11,UBE2E2,DISC1,SORL1,FCHSD2,GNAQ,ATP8B4,DSCAM,ABCC4,PLXDC2,ANKRD44,PTPRJ,ARHGAP24,ARHGAP22,ST6GAL1,MAP4K4,TCF12,MED13L,QKI,KCNQ3,HDAC9,ELMO1,ARHGAP26,MEF2A,SSH2,ZSWIM6,ZFAND3,ZBTB20,SLC8A1,SFMBT2,EPB41L2,DOCK4,NAV3,HS3ST4,APBB1IP,ADAM28,ZFHX3,ST6GALNAC3,PICALM,SYNDIG1,MEF2C,MAML2,DOCK8,DIP2B,MAML3,FRMD4A,ITPR2,TBC1D22A,SLC9A9
4.758e-02	-3.05	GI Alpha 1, domain 2-like	gene3d domains	1.10.400.10	16	1	14470	44	GNAQ
4.774e-02	-3.04	FAM25C (family with sequence similarity 25 member C)	protein interactions	644054	19	1	19454	50	ZFAND3
4.774e-02	-3.04	PLCB2 (phospholipase C beta 2)	protein interactions	5330	19	1	19454	50	GNAQ
4.774e-02	-3.04	ZNF138 (zinc finger protein 138)	protein interactions	7697	19	1	19454	50	ARHGAP24
4.774e-02	-3.04	DRD1 (dopamine receptor D1)	protein interactions	1812	19	1	19454	50	EPB41L2
4.774e-02	-3.04	INKA1 (inka box actin regulator 1)	protein interactions	389119	19	1	19454	50	ZBTB20
4.774e-02	-3.04	SP6 (Sp6 transcription factor)	protein interactions	80320	19	1	19454	50	SORL1
4.774e-02	-3.04	LRRC42 (leucine rich repeat containing 42)	protein interactions	115353	19	1	19454	50	PLXDC2
4.774e-02	-3.04	ACADS (acyl-CoA dehydrogenase short chain)	protein interactions	35	19	1	19454	50	ARHGAP26
4.774e-02	-3.04	CRYBB1 (crystallin beta B1)	protein interactions	1414	19	1	19454	50	DISC1
4.774e-02	-3.04	ZNF197 (zinc finger protein 197)	protein interactions	10168	19	1	19454	50	DISC1
4.774e-02	-3.04	RIT2 (Ras like without CAAX 2)	protein interactions	6014	19	1	19454	50	ARHGAP24
4.774e-02	-3.04	EGFL6 (EGF like domain multiple 6)	protein interactions	25975	19	1	19454	50	SORL1
4.779e-02	-3.04	NEFL (neurofilament light chain)	protein interactions	4747	136	2	19454	50	ARHGAP24,DSCAM
4.786e-02	-3.04	regulation of response to stimulus	biological process	GO:0048583	4104	16	18204	47	PTPRJ,ARHGAP26,MEF2A,SORL1,LDLRAD4,DISC1,PICALM,ARHGAP22,DOCK8,GNAQ,MEF2C,ARHGAP24,ST6GAL1,CHST11,MAP4K4,DSCAM
4.787e-02	-3.04	regulation of signal transduction	biological process	GO:0009966	3114	13	18204	47	MEF2C,DOCK8,GNAQ,CHST11,ARHGAP24,MAP4K4,ARHGAP26,PTPRJ,DISC1,LDLRAD4,SORL1,ARHGAP22,PICALM
4.793e-02	-3.04	skin-back-malignant_melanoma	COSMIC cancer mutations	skin-back-malignant_melanoma	280	3	16828	49	GNAQ,PTPRJ,ADAM28
4.795e-02	-3.04	microvillus organization	biological process	GO:0032528	19	1	18204	47	MAP4K4
4.795e-02	-3.04	positive regulation of macrophage chemotaxis	biological process	GO:0010759	19	1	18204	47	PTPRJ
4.795e-02	-3.04	regulation of skeletal muscle cell differentiation	biological process	GO:2001014	19	1	18204	47	MEF2C
4.795e-02	-3.04	vascular associated smooth muscle cell differentiation	biological process	GO:0035886	19	1	18204	47	QKI
4.795e-02	-3.04	positive regulation of Ras protein signal transduction	biological process	GO:0046579	19	1	18204	47	PICALM
4.795e-02	-3.04	mitochondrion distribution	biological process	GO:0048311	19	1	18204	47	MEF2A
4.795e-02	-3.04	post-anal tail morphogenesis	biological process	GO:0036342	19	1	18204	47	CHST11
4.795e-02	-3.04	detection of temperature stimulus involved in sensory perception of pain	biological process	GO:0050965	19	1	18204	47	DISC1
4.795e-02	-3.04	chondroitin sulfate biosynthetic process	biological process	GO:0030206	19	1	18204	47	CHST11
4.795e-02	-3.04	GABAergic neuron differentiation	biological process	GO:0097154	19	1	18204	47	ZSWIM6
4.809e-02	-3.03	N-glycan biosynthesis, complex type	KEGG pathways	hsa_M00075	16	1	7161	22	ST6GAL1
4.809e-02	-3.03	N-glycan biosynthesis, complex type	KEGG pathways	M00075	16	1	7161	22	ST6GAL1
4.814e-02	-3.03	protein dephosphorylation	biological process	GO:0006470	136	2	18204	47	PTPRJ,SSH2
4.839e-02	-3.03	thymus-thymoma	COSMIC cancer mutations	thymus-thymoma	17	1	16828	49	GNAQ
4.839e-02	-3.03	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	COSMIC cancer mutations	central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I	17	1	16828	49	QKI
4.839e-02	-3.03	thymoma	COSMIC cancer mutations	thymoma	17	1	16828	49	GNAQ
4.839e-02	-3.03	optic_nerve	COSMIC cancer mutations	optic_nerve	17	1	16828	49	QKI
4.842e-02	-3.03	TOX4 (TOX high mobility group box family member 4)	protein interactions	9878	137	2	19454	50	EPB41L2,ARHGAP26
4.844e-02	-3.03	ADAM_CR	pfam domains	PF08516	18	1	17795	49	ADAM28
4.845e-02	-3.03	asymmetric synapse	cellular component	GO:0032279	333	3	19108	47	SYNDIG1,SLC8A1,DISC1
4.861e-02	-3.02	intracellularly gated calcium channel activity	molecular function	GO:0015278	18	1	18094	50	ITPR2
4.861e-02	-3.02	lipoprotein particle receptor activity	molecular function	GO:0030228	18	1	18094	50	SORL1
4.877e-02	-3.02	cell recognition	biological process	GO:0008037	137	2	18204	47	DSCAM,DOCK8
4.902e-02	-3.02	lung-carcinoma-undifferentiated_carcinoma	COSMIC cancer mutations	lung-carcinoma-undifferentiated_carcinoma	1408	8	16828	49	MAML3,PICALM,GNAQ,ARHGAP26,MEF2A,MEF2C,MAML2,TCF12
4.906e-02	-3.01	Integration of energy metabolism	REACTOME pathways	R-HSA-163685	111	2	10285	33	ITPR2,GNAQ
4.941e-02	-3.01	sodium ion transmembrane transport	biological process	GO:0035725	138	2	18204	47	SLC9A9,SLC8A1
4.941e-02	-3.01	negative regulation of nervous system development	biological process	GO:0051961	138	2	18204	47	SORL1,DIP2B
4.941e-02	-3.01	regulation of protein localization to cell periphery	biological process	GO:1904375	138	2	18204	47	EPB41L2,PICALM
4.947e-02	-3.01	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	biological process	GO:0090092	320	3	18204	47	LDLRAD4,SORL1,CHST11
4.962e-02	-3.00	thalamus	COSMIC cancer mutations	thalamus	284	3	16828	49	QKI,ZFHX3,GNAQ
4.968e-02	-3.00	DUSP22 (dual specificity phosphatase 22)	protein interactions	56940	139	2	19454	50	GNAQ,QKI
4.968e-02	-3.00	MAGI1 (membrane associated guanylate kinase, WW and PDZ domain containing 1)	protein interactions	9223	139	2	19454	50	FCHSD2,LDLRAD4
4.968e-02	-3.00	NEFM (neurofilament medium chain)	protein interactions	4741	139	2	19454	50	DISC1,DSCAM
4.977e-02	-3.00	ITGB1 (integrin subunit beta 1)	protein interactions	3688	322	3	19454	50	MAP4K4,PICALM,MEF2A
4.985e-02	-3.00	wound healing	biological process	GO:0042060	321	3	18204	47	PTPRJ,ARHGAP24,GNAQ
4.993e-02	-3.00	response to organic substance	biological process	GO:0010033	2498	11	18204	47	HDAC9,PTPRJ,TCF12,ZBTB20,SLC8A1,GNAQ,DOCK8,MEF2C,ST6GAL1,KCNQ3,ITPR2