TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols WP536 Calcium Regulation in the Cardiac Cell 0.0114368909957672 -4.47091109606985 151 3 0.176470588235294 17 5310 6000,775,6262 RGS7,CACNA1C,RYR2 WP2267 Synaptic Vesicle Pathway 0.0116454332990935 -4.4528411673133 52 2 0.117647058823529 17 5310 10815,440279 CPLX1,UNC13C WP1603 Nicotine Activity on Chromaffin Cells 0.0127482441101937 -4.36236173370909 4 1 0.0588235294117647 17 5310 775 CACNA1C WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy 0.0239289871633872 -3.73266470293095 76 2 0.117647058823529 17 5310 775,6262 CACNA1C,RYR2 WP1423 Ganglio Sphingolipid Metabolism 0.040874746353827 -3.19724285519493 13 1 0.0588235294117647 17 5310 29906 ST8SIA5 WP3679 Cell-type Dependent Selectivity of CCK2R Signaling 0.040874746353827 -3.19724285519493 13 1 0.0588235294117647 17 5310 6262 RYR2 WP501 GPCRs, Class C Metabotropic glutamate, pheromone 0.050081419349586 -2.99410521094682 16 1 0.0588235294117647 17 5310 9568 GABBR2 WP2059 Alzheimers Disease 0.079864204624262 -2.52742752879235 148 2 0.117647058823529 17 5310 2903,775 GRIN2A,CACNA1C WP289 Myometrial Relaxation and Contraction Pathways 0.0893874722938702 -2.41477473756298 158 2 0.117647058823529 17 5310 6000,6262 RGS7,RYR2 WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 0.09329158072012 -2.37202541399889 162 2 0.117647058823529 17 5310 2554,6262 GABRA1,RYR2 WP500 Glycogen Metabolism 0.109366164521404 -2.21305371908595 36 1 0.0588235294117647 17 5310 5526 PPP2R5B WP2636 Common Pathways Underlying Drug Addiction 0.126460993806009 -2.06782136772361 42 1 0.0588235294117647 17 5310 2903 GRIN2A WP3594 Circadian rythm related genes 0.140362708992951 -1.96352542813312 207 2 0.117647058823529 17 5310 4987,3778 OPRL1,KCNMA1 WP558 Complement and Coagulation Cascades 0.175911389213479 -1.73777488110571 60 1 0.0588235294117647 17 5310 1380 CR2 WP3584 MECP2 and Associated Rett Syndrome 0.181240209975586 -1.70793200063396 62 1 0.0588235294117647 17 5310 54715 RBFOX1 WP24 Peptide GPCRs 0.212538275031381 -1.5486331890422 74 1 0.0588235294117647 17 5310 4987 OPRL1 WP231 TNF alpha Signaling Pathway 0.262212705425647 -1.3385992518256 94 1 0.0588235294117647 17 5310 283455 KSR2 WP23 B Cell Receptor Signaling Pathway 0.271786918017603 -1.30273690933732 98 1 0.0588235294117647 17 5310 1380 CR2 WP411 mRNA Processing 0.348575974657729 -1.05389906778439 132 1 0.0588235294117647 17 5310 56853 CELF4 WP2858 Ectoderm Differentiation 0.371741317900104 -0.989557048588157 143 1 0.0588235294117647 17 5310 460 ASTN1 WP455 GPCRs, Class A Rhodopsin-like 0.573187795961729 -0.556541874319452 259 1 0.0588235294117647 17 5310 4987 OPRL1 WP2359 Parkin-Ubiquitin Proteasomal System pathway 0.999999999988756 -1.1244013171692e-11 70 0 0 17 5310 WP428 Wnt Signaling Pathway 0.999999999988756 -1.1244013171692e-11 70 0 0 17 5310 WP2276 Glial Cell Differentiation 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP3635 Insulin signalling in human adipocytes (diabetic condition) 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP136 Phase I biotransformations, non P450 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP1604 Codeine and Morphine Metabolism 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP3634 Insulin signalling in human adipocytes (normal condition) 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP1589 Folate-Alcohol and Cancer Pathway 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP237 Glucocorticoid & Mineralcorticoid Metabolism 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP2338 miRNA Biogenesis 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP2485 NAD Biosynthesis II (from tryptophan) 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP3655 Hypothetical Craniofacial Development Pathway 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP3407 FTO Obesity Variant Mechanism 0.999999999991682 -8.31765653425986e-12 8 0 0 17 5310 WP1422 Sphingolipid Metabolism 0.999999999994965 -5.03454188165351e-12 20 0 0 17 5310 WP1742 TP53 Network 0.999999999994965 -5.03454188165351e-12 20 0 0 17 5310 WP497 Urea cycle and metabolism of amino groups 0.999999999994965 -5.03454188165351e-12 20 0 0 17 5310 WP391 Mitochondrial Gene Expression 0.999999999994965 -5.03454188165351e-12 20 0 0 17 5310 WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling 0.999999999994965 -5.03454188165351e-12 20 0 0 17 5310 WP516 Hypertrophy Model 0.999999999994965 -5.03454188165351e-12 20 0 0 17 5310 WP3871 Valproic acid pathway 0.999999999995096 -4.9043930180376e-12 13 0 0 17 5310 WP3892 Development of pulmonary dendritic cells and macrophage subsets 0.999999999995096 -4.9043930180376e-12 13 0 0 17 5310 WP2881 Estrogen Receptor Pathway 0.999999999995096 -4.9043930180376e-12 13 0 0 17 5310 WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation 0.999999999995096 -4.9043930180376e-12 13 0 0 17 5310 WP186 Homologous recombination 0.999999999995096 -4.9043930180376e-12 13 0 0 17 5310 WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation 0.999999999995096 -4.9043930180376e-12 13 0 0 17 5310 WP1434 Osteopontin Signaling 0.999999999995096 -4.9043930180376e-12 13 0 0 17 5310 WP383 Striated Muscle Contraction 0.999999999997503 -2.49739719372893e-12 38 0 0 17 5310 WP2526 PDGF Pathway 0.999999999997503 -2.49739719372893e-12 38 0 0 17 5310 WP2447 Amyotrophic lateral sclerosis (ALS) 0.999999999997503 -2.49739719372893e-12 38 0 0 17 5310 WP2029 Cell Differentiation - Index 0.999999999997503 -2.49739719372893e-12 38 0 0 17 5310 WP2261 Signaling Pathways in Glioblastoma 0.999999999997565 -2.43522319286725e-12 83 0 0 17 5310 WP2371 Parkinsons Disease Pathway 0.999999999997565 -2.43522319286725e-12 83 0 0 17 5310 WP2509 Nanoparticle triggered autophagic cell death 0.99999999999826 -1.74053211312702e-12 24 0 0 17 5310 WP1539 Angiogenesis 0.99999999999826 -1.74053211312702e-12 24 0 0 17 5310 WP334 GPCRs, Class B Secretin-like 0.99999999999826 -1.74053211312702e-12 24 0 0 17 5310 WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia 0.99999999999826 -1.74053211312702e-12 24 0 0 17 5310 WP262 EBV LMP1 signaling 0.99999999999826 -1.74053211312702e-12 24 0 0 17 5310 WP2795 Cardiac Hypertrophic Response 0.999999999998375 -1.62512690604758e-12 57 0 0 17 5310 WP195 IL-1 signaling pathway 0.999999999998375 -1.62512690604758e-12 57 0 0 17 5310 WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 0.999999999998399 -1.6005802753379e-12 44 0 0 17 5310 WP716 Vitamin A and Carotenoid Metabolism 0.999999999998399 -1.6005802753379e-12 44 0 0 17 5310 WP2332 Interleukin-11 Signaling Pathway 0.999999999998399 -1.6005802753379e-12 44 0 0 17 5310 WP2857 Mesodermal Commitment Pathway 0.999999999998701 -1.29921339849047e-12 155 0 0 17 5310 WP530 Cytokines and Inflammatory Response 0.99999999999874 -1.25960864760634e-12 26 0 0 17 5310 WP26 Signal Transduction of S1P Receptor 0.99999999999874 -1.25960864760634e-12 26 0 0 17 5310 WP2878 PPAR Alpha Pathway 0.99999999999874 -1.25960864760634e-12 26 0 0 17 5310 WP325 Triacylglyceride Synthesis 0.99999999999874 -1.25960864760634e-12 26 0 0 17 5310 WP698 Glucuronidation 0.99999999999874 -1.25960864760634e-12 26 0 0 17 5310 WP581 EPO Receptor Signaling 0.99999999999874 -1.25960864760634e-12 26 0 0 17 5310 WP304 Kit receptor signaling pathway 0.999999999998742 -1.25828365697979e-12 60 0 0 17 5310 WP3527 Preimplantation Embryo 0.999999999998742 -1.25828365697979e-12 60 0 0 17 5310 WP2369 Histone Modifications 0.999999999999652 -3.47888468841773e-13 69 0 0 17 5310 WP176 Folate Metabolism 0.999999999999652 -3.47888468841773e-13 69 0 0 17 5310 WP707 DNA Damage Response 0.999999999999652 -3.47888468841773e-13 69 0 0 17 5310 WP254 Apoptosis 0.999999999999697 -3.0301724787586e-13 86 0 0 17 5310 WP477 Cytoplasmic Ribosomal Proteins 0.999999999999871 -1.28574668951627e-13 90 0 0 17 5310 WP138 Androgen receptor signaling pathway 0.999999999999871 -1.28574668951627e-13 90 0 0 17 5310 WP2012 miRs in Muscle Cell Differentiation 1.00000000000015 1.5244394517798e-13 36 0 0 17 5310 WP3298 Melatonin metabolism and effects 1.00000000000015 1.5244394517798e-13 36 0 0 17 5310 WP1424 Globo Sphingolipid Metabolism 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP1584 Type II diabetes mellitus 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP357 Fatty Acid Biosynthesis 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP3645 NAD+ biosynthetic pathways 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP3599 Transcription factor regulation in adipogenesis 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP167 Eicosanoid Synthesis 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP100 Glutathione metabolism 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP272 Blood Clotting Cascade 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP545 Complement Activation 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex 1.00000000000086 8.59533934560107e-13 22 0 0 17 5310 WP49 IL-2 Signaling Pathway 1.00000000000107 1.07344399302621e-12 42 0 0 17 5310 WP466 DNA Replication 1.00000000000107 1.07344399302621e-12 42 0 0 17 5310 WP405 Eukaryotic Transcription Initiation 1.00000000000107 1.07344399302621e-12 42 0 0 17 5310 WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 1.00000000000107 1.07344399302621e-12 42 0 0 17 5310 WP2884 NRF2 pathway 1.00000000000109 1.09357076419518e-12 143 0 0 17 5310 WP1545 miRNAs involved in DNA damage response 1.00000000000151 1.50589506027176e-12 50 0 0 17 5310 WP2637 Structural Pathway of Interleukin 1 (IL-1) 1.00000000000151 1.50589506027176e-12 50 0 0 17 5310 WP2889 Oxytocin signaling 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP1941 Peroxisomal beta-oxidation of tetracosanoyl-CoA 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP3633 Caffeine and Theobromine metabolism 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP2253 Pilocytic astrocytoma 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP521 Amino acid conjugation of benzoic acid 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP733 Serotonin Receptor 2 and STAT3 Signaling 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP3302 eIF5A regulation in response to inhibition of the nuclear export system 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP690 Polyol Pathway 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP2491 Diclofenac Metabolic Pathway 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP897 Androgen receptor signaling pathway 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP1133 Androgen receptor signaling pathway 1.00000000000183 1.83425307270843e-12 4 0 0 17 5310 WP1601 Fluoropyrimidine Activity 1.00000000000216 2.15837381000306e-12 34 0 0 17 5310 WP400 p38 MAPK Signaling Pathway 1.00000000000216 2.15837381000306e-12 34 0 0 17 5310 WP143 Fatty Acid Beta Oxidation 1.00000000000216 2.15837381000306e-12 34 0 0 17 5310 WP313 Signaling of Hepatocyte Growth Factor Receptor 1.00000000000216 2.15837381000306e-12 34 0 0 17 5310 WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 1.0000000000023 2.2977040475966e-12 47 0 0 17 5310 WP560 TGF-beta Receptor Signaling 1.00000000000242 2.42442017900918e-12 58 0 0 17 5310 WP710 DNA Damage Response (only ATM dependent) 1.00000000000247 2.47408361739396e-12 114 0 0 17 5310 WP3845 Canonical and Non-canonical Notch signaling 1.00000000000256 2.5606909419009e-12 27 0 0 17 5310 WP2035 Follicle Stimulating Hormone (FSH) signaling pathway 1.00000000000256 2.5606909419009e-12 27 0 0 17 5310 WP382 MAPK Signaling Pathway 1.00000000000257 2.56830882836739e-12 170 0 0 17 5310 WP422 MAPK Cascade 1.00000000000268 2.67930079240724e-12 29 0 0 17 5310 WP2643 Nanoparticle-mediated activation of receptor signaling 1.00000000000268 2.67930079240724e-12 29 0 0 17 5310 WP2583 T-Cell Receptor and Co-stimulatory Signaling 1.00000000000268 2.67930079240724e-12 29 0 0 17 5310 WP3613 Photodynamic therapy-induced unfolded protein response 1.00000000000268 2.67930079240724e-12 29 0 0 17 5310 WP111 Electron Transport Chain 1.00000000000275 2.74678446245257e-12 92 0 0 17 5310 WP2542 Sulindac Metabolic Pathway 1.00000000000292 2.92510412267896e-12 5 0 0 17 5310 WP2597 Secretion of Hydrochloric Acid in Parietal Cells 1.00000000000292 2.92510412267896e-12 5 0 0 17 5310 WP3596 miR-517 relationship with ARCN1 and USP1 1.00000000000292 2.92510412267896e-12 5 0 0 17 5310 WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer 1.00000000000292 2.92510412267896e-12 5 0 0 17 5310 WP688 Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs) 1.00000000000292 2.92510412267896e-12 5 0 0 17 5310 WP311 Synthesis and Degradation of Ketone Bodies 1.00000000000292 2.92510412267896e-12 5 0 0 17 5310 WP61 Notch Signaling Pathway 1.00000000000304 3.04350789770798e-12 62 0 0 17 5310 WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 1.00000000000304 3.04350789770798e-12 62 0 0 17 5310 WP2361 Gastric Cancer Network 1 1.00000000000321 3.21507175766802e-12 28 0 0 17 5310 WP2249 Metastatic brain tumor 1.00000000000321 3.21507175766802e-12 28 0 0 17 5310 WP3585 Cytosine methylation 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP3593 miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP288 NLR Proteins 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP3300 Dual hijack model of Vif in HIV infection 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP3674 Tgif disruption of Shh signaling 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP531 Mismatch repair 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP3875 ATR Signaling 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP696 Benzo(a)pyrene metabolism 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP2942 DDX1 as a regulatory component of the Drosha microprocessor 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP561 Heme Biosynthesis 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP3297 EV release from cardiac cells and their functional effects 1.00000000000324 3.24310000408719e-12 9 0 0 17 5310 WP727 Monoamine Transport 1.00000000000335 3.34758539567764e-12 32 0 0 17 5310 WP2875 Constitutive Androstane Receptor Pathway 1.00000000000335 3.34758539567764e-12 32 0 0 17 5310 WP3893 Development and heterogeneity of the ILC family 1.00000000000335 3.34758539567764e-12 32 0 0 17 5310 WP34 Ovarian Infertility Genes 1.00000000000335 3.34758539567764e-12 32 0 0 17 5310 WP3858 Toll-like Receptor Signaling 1.00000000000335 3.34758539567764e-12 32 0 0 17 5310 WP2525 Trans-sulfuration and one carbon metabolism 1.00000000000335 3.34758539567764e-12 32 0 0 17 5310 WP2828 Bladder Cancer 1.00000000000335 3.34758539567764e-12 32 0 0 17 5310 WP2873 Aryl Hydrocarbon Receptor Pathway 1.00000000000339 3.392349356081e-12 48 0 0 17 5310 WP2848 Differentiation Pathway 1.00000000000339 3.392349356081e-12 48 0 0 17 5310 WP2849 Hematopoietic Stem Cell Differentiation 1.00000000000339 3.392349356081e-12 48 0 0 17 5310 WP2586 Aryl Hydrocarbon Receptor 1.00000000000339 3.392349356081e-12 48 0 0 17 5310 WP3865 RIG-I-like Receptor Signaling 1.00000000000347 3.47334242511067e-12 61 0 0 17 5310 WP481 Insulin Signaling 1.00000000000383 3.83058183389485e-12 161 0 0 17 5310 WP2324 AGE/RAGE pathway 1.00000000000408 4.07997830641807e-12 66 0 0 17 5310 WP183 Proteasome Degradation 1.00000000000408 4.07997830641807e-12 66 0 0 17 5310 WP3651 Pathways Affected in Adenoid Cystic Carcinoma 1.00000000000408 4.07997830641807e-12 66 0 0 17 5310 WP2374 Oncostatin M Signaling Pathway 1.00000000000408 4.07997830641807e-12 66 0 0 17 5310 WP188 Focal Adhesion 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP2190 One carbon donor 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP108 Selenium metabolism/Selenoproteins 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP2536 Colchicine Metabolic Pathway 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP1 Statin Pathway 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP3191 TSLP Signaling Pathway 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP661 Glucose Homeostasis 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP3627 Gut-Liver Indole Metabolism 1.00000000000431 4.3061981931658e-12 1 0 0 17 5310 WP1772 Apoptosis Modulation and Signaling 1.00000000000436 4.36176722824594e-12 94 0 0 17 5310 WP2355 Corticotropin-releasing hormone signaling pathway 1.00000000000464 4.64440165974235e-12 93 0 0 17 5310 WP1530 miRNA Regulation of DNA Damage Response 1.00000000000464 4.64440165974235e-12 93 0 0 17 5310 WP3624 Lung fibrosis 1.0000000000048 4.80463830133064e-12 63 0 0 17 5310 WP43 Oxidation by Cytochrome P450 1.0000000000048 4.80463830133064e-12 63 0 0 17 5310 WP35 G Protein Signaling Pathways 1.00000000000505 5.0525032478182e-12 95 0 0 17 5310 WP117 GPCRs, Other 1.00000000000505 5.0525032478182e-12 95 0 0 17 5310 WP3878 ATM Signaling Network in Development and Disease 1.0000000000051 5.10340375033069e-12 46 0 0 17 5310 WP1591 Heart Development 1.0000000000051 5.10340375033069e-12 46 0 0 17 5310 WP28 Selenium Metabolism and Selenoproteins 1.0000000000051 5.10340375033069e-12 46 0 0 17 5310 WP268 Notch Signaling Pathway 1.0000000000051 5.10340375033069e-12 46 0 0 17 5310 WP1971 Integrated Cancer Pathway 1.0000000000051 5.10340375033069e-12 46 0 0 17 5310 WP465 Tryptophan metabolism 1.0000000000051 5.10340375033069e-12 46 0 0 17 5310 WP45 G1 to S cell cycle control 1.00000000000513 5.12920127716024e-12 68 0 0 17 5310 WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway 1.00000000000513 5.12920127716024e-12 68 0 0 17 5310 WP3303 Rac1/Pak1/p38/MMP-2 pathway 1.00000000000513 5.12920127716024e-12 68 0 0 17 5310 WP1403 AMP-activated Protein Kinase (AMPK) Signaling 1.00000000000513 5.12920127716024e-12 68 0 0 17 5310 WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways 1.00000000000513 5.12920127716024e-12 68 0 0 17 5310 WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway 1.00000000000515 5.1458089067809e-12 55 0 0 17 5310 WP585 Interferon type I signaling pathways 1.00000000000515 5.1458089067809e-12 55 0 0 17 5310 WP2272 Pathogenic Escherichia coli infection 1.00000000000515 5.1458089067809e-12 55 0 0 17 5310 WP395 IL-4 Signaling Pathway 1.00000000000515 5.1458089067809e-12 55 0 0 17 5310 WP3611 Photodynamic therapy-induced AP-1 survival signaling. 1.00000000000517 5.17279349581428e-12 51 0 0 17 5310 WP3646 Hepatitis C and Hepatocellular Carcinoma 1.00000000000517 5.17279349581428e-12 51 0 0 17 5310 WP2034 Leptin signaling pathway 1.00000000000543 5.43329819870942e-12 76 0 0 17 5310 WP2037 Prolactin Signaling Pathway 1.00000000000543 5.43329819870942e-12 76 0 0 17 5310 WP3891 Benzene metabolism 1.0000000000056 5.5958450889148e-12 6 0 0 17 5310 WP1981 Thyroxine (Thyroid Hormone) Production 1.0000000000056 5.5958450889148e-12 6 0 0 17 5310 WP694 Arylamine metabolism 1.0000000000056 5.5958450889148e-12 6 0 0 17 5310 WP1600 Nicotine Metabolism 1.0000000000056 5.5958450889148e-12 6 0 0 17 5310 WP2377 Integrated Pancreatic Cancer Pathway 1.0000000000056 5.60358398665144e-12 197 0 0 17 5310 WP179 Cell Cycle 1.00000000000584 5.8361853516308e-12 105 0 0 17 5310 WP437 EGF/EGFR Signaling Pathway 1.00000000000596 5.95876537129093e-12 162 0 0 17 5310 WP3408 Evolocumab Mechanism 1.00000000000602 6.02354464626895e-12 3 0 0 17 5310 WP2846 Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation 1.00000000000602 6.02354464626895e-12 3 0 0 17 5310 WP2436 Dopamine metabolism 1.00000000000604 6.0404564125448e-12 14 0 0 17 5310 WP322 Osteoblast Signaling 1.00000000000604 6.0404564125448e-12 14 0 0 17 5310 WP229 Irinotecan Pathway 1.00000000000604 6.0404564125448e-12 14 0 0 17 5310 WP3853 ERK Pathway in Huntington's Disease 1.00000000000604 6.0404564125448e-12 14 0 0 17 5310 WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 1.00000000000605 6.05176733292217e-12 23 0 0 17 5310 WP712 Estrogen signaling pathway 1.00000000000605 6.05176733292217e-12 23 0 0 17 5310 WP692 Sulfation Biotransformation Reaction 1.0000000000061 6.09719989260027e-12 18 0 0 17 5310 WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression 1.0000000000061 6.09719989260027e-12 18 0 0 17 5310 WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds 1.0000000000061 6.09719989260027e-12 18 0 0 17 5310 WP3413 NOTCH1 regulation of human endothelial cell calcification 1.0000000000061 6.09719989260027e-12 18 0 0 17 5310 WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition 1.0000000000061 6.09719989260027e-12 18 0 0 17 5310 WP1544 MicroRNAs in cardiomyocyte hypertrophy 1.00000000000629 6.2929993873196e-12 102 0 0 17 5310 WP2064 Neural Crest Differentiation 1.00000000000629 6.2929993873196e-12 102 0 0 17 5310 WP2853 Endoderm Differentiation 1.00000000000636 6.35562538458991e-12 145 0 0 17 5310 WP1449 Regulation of toll-like receptor signaling pathway 1.00000000000636 6.35562538458991e-12 145 0 0 17 5310 WP3915 Angiopoietin Like Protein 8 Regulatory Pathway 1.00000000000644 6.44349231734371e-12 132 0 0 17 5310 WP2879 Farnesoid X Receptor Pathway 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP404 Nucleotide Metabolism 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP384 Apoptosis Modulation by HSP70 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP1992 TarBasePathway 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP734 Serotonin Receptor 4/6/7 and NR3C Signaling 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP22 IL-9 Signaling Pathway 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP697 Estrogen metabolism 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP247 Small Ligand GPCRs 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP3287 Overview of nanoparticle effects 1.00000000000646 6.45947352313006e-12 19 0 0 17 5310 WP364 IL-6 signaling pathway 1.00000000000701 7.00935196936389e-12 43 0 0 17 5310 WP2911 miRNA targets in ECM and membrane receptors 1.00000000000701 7.00935196936389e-12 43 0 0 17 5310 WP2328 Allograft Rejection 1.00000000000703 7.02734171471e-12 80 0 0 17 5310 WP306 Focal Adhesion 1.0000000000071 7.09630616230688e-12 195 0 0 17 5310 WP185 Integrin-mediated Cell Adhesion 1.00000000000714 7.14305885303938e-12 103 0 0 17 5310 WP75 Toll-like Receptor Signaling Pathway 1.00000000000714 7.14305885303938e-12 103 0 0 17 5310 WP3874 Canonical and Non-Canonical TGF-B signaling 1.00000000000736 7.36128629693737e-12 17 0 0 17 5310 WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 1.00000000000736 7.36128629693737e-12 17 0 0 17 5310 WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation 1.00000000000736 7.36128629693737e-12 17 0 0 17 5310 WP78 TCA Cycle 1.00000000000736 7.36128629693737e-12 17 0 0 17 5310 WP2289 Drug Induction of Bile Acid Pathway 1.00000000000736 7.36128629693737e-12 17 0 0 17 5310 WP2916 Interactome of polycomb repressive complex 2 (PRC2) 1.00000000000736 7.36128629693737e-12 17 0 0 17 5310 WP554 ACE Inhibitor Pathway 1.00000000000736 7.36128629693737e-12 17 0 0 17 5310 WP408 Oxidative Stress 1.00000000000756 7.55828233874557e-12 31 0 0 17 5310 WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 1.00000000000756 7.55828233874557e-12 31 0 0 17 5310 WP2112 IL17 signaling pathway 1.00000000000756 7.55828233874557e-12 31 0 0 17 5310 WP474 Endochondral Ossification 1.00000000000774 7.73612187919724e-12 65 0 0 17 5310 WP170 Nuclear Receptors 1.00000000000778 7.77676020449447e-12 39 0 0 17 5310 WP53 ID signaling pathway 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP47 Hedgehog Signaling Pathway 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP3644 NAD+ metabolism 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP12 Osteoclast Signaling 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP550 Biogenic Amine Synthesis 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP1946 Cori Cycle 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer 1.00000000000779 7.78821244175982e-12 16 0 0 17 5310 WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway 1.0000000000081 8.09696107436785e-12 41 0 0 17 5310 WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP2290 RalA downstream regulated genes 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP2007 Iron metabolism in placenta 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP3672 LncRNA-mediated mechanisms of therapeutic resistance 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP106 Alanine and aspartate metabolism 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP1559 TFs Regulate miRNAs related to cardiac hypertrophy 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness 1.00000000000828 8.27672891606686e-12 12 0 0 17 5310 WP69 T-Cell antigen Receptor (TCR) Signaling Pathway 1.00000000000828 8.2787435363723e-12 91 0 0 17 5310 WP3925 Amino Acid metabolism 1.00000000000828 8.2787435363723e-12 91 0 0 17 5310 WP3614 Photodynamic therapy-induced HIF-1 survival signaling 1.00000000000858 8.57549272251969e-12 37 0 0 17 5310 WP619 Type II interferon signaling (IFNG) 1.00000000000858 8.57549272251969e-12 37 0 0 17 5310 WP3529 Zinc homeostasis 1.00000000000858 8.57549272251969e-12 37 0 0 17 5310 WP1471 Target Of Rapamycin (TOR) Signaling 1.00000000000858 8.57549272251969e-12 37 0 0 17 5310 WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR 1.00000000000858 8.57549272251969e-12 37 0 0 17 5310 WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 1.00000000000871 8.70721479930245e-12 144 0 0 17 5310 WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 1.00000000000873 8.73171821807695e-12 74 0 0 17 5310 WP3656 Interleukin-1 Induced Activation of NF-kappa-B 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP1531 Vitamin D Metabolism 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP2874 Liver X Receptor Pathway 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP3601 Composition of Lipid Particles 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP2113 Type III interferon signaling 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP496 Steroid Biosynthesis 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP704 Methylation Pathways 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP2333 Trans-sulfuration pathway 1.00000000000883 8.82741565450922e-12 10 0 0 17 5310 WP299 Nuclear Receptors in Lipid Metabolism and Toxicity 1.00000000000901 9.01255655066133e-12 35 0 0 17 5310 WP3617 Photodynamic therapy-induced NF-kB survival signaling 1.00000000000901 9.01255655066133e-12 35 0 0 17 5310 WP244 Alpha 6 Beta 4 signaling pathway 1.00000000000901 9.01255655066133e-12 35 0 0 17 5310 WP197 Cholesterol Biosynthesis 1.00000000000902 9.01810414623165e-12 15 0 0 17 5310 WP206 Fatty Acid Omega Oxidation 1.00000000000902 9.01810414623165e-12 15 0 0 17 5310 WP2435 Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis 1.00000000000902 9.01810414623165e-12 15 0 0 17 5310 WP3 Transcriptional activation by NRF2 1.00000000000902 9.01810414623165e-12 15 0 0 17 5310 WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 1.00000000000906 9.05961334129399e-12 30 0 0 17 5310 WP3851 TLR4 Signaling and Tolerance 1.00000000000906 9.05961334129399e-12 30 0 0 17 5310 WP2870 Extracellular vesicle-mediated signaling in recipient cells 1.00000000000906 9.05961334129399e-12 30 0 0 17 5310 WP2855 Dopaminergic Neurogenesis 1.00000000000906 9.05961334129399e-12 30 0 0 17 5310 WP129 Matrix Metalloproteinases 1.00000000000906 9.05961334129399e-12 30 0 0 17 5310 WP98 Prostaglandin Synthesis and Regulation 1.00000000000906 9.05961334129399e-12 30 0 0 17 5310 WP241 One Carbon Metabolism 1.00000000000906 9.05961334129399e-12 30 0 0 17 5310 WP534 Glycolysis and Gluconeogenesis 1.0000000000099 9.90192062918776e-12 49 0 0 17 5310 WP410 Diurnally Regulated Genes with Circadian Orthologs 1.0000000000099 9.90192062918776e-12 49 0 0 17 5310 WP286 IL-3 Signaling Pathway 1.0000000000099 9.90192062918776e-12 49 0 0 17 5310 WP1984 Integrated Breast Cancer Pathway 1.00000000001007 1.0068161886396e-11 154 0 0 17 5310 WP2895 Differentiation of white and brown adipocyte 1.00000000001015 1.01508321952227e-11 25 0 0 17 5310 WP205 IL-7 Signaling Pathway 1.00000000001015 1.01508321952227e-11 25 0 0 17 5310 WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease 1.00000000001015 1.01508321952227e-11 25 0 0 17 5310 WP2865 IL1 and megakaryocytes in obesity 1.00000000001015 1.01508321952227e-11 25 0 0 17 5310 WP1528 Physiological and Pathological Hypertrophy of the Heart 1.00000000001015 1.01508321952227e-11 25 0 0 17 5310 WP2363 Gastric Cancer Network 2 1.00000000001021 1.021228073383e-11 33 0 0 17 5310 WP453 Inflammatory Response Pathway 1.00000000001021 1.021228073383e-11 33 0 0 17 5310 WP2197 Endothelin Pathways 1.00000000001021 1.021228073383e-11 33 0 0 17 5310 WP430 Statin Pathway 1.00000000001021 1.021228073383e-11 33 0 0 17 5310 WP58 Monoamine GPCRs 1.00000000001021 1.021228073383e-11 33 0 0 17 5310 WP3676 BDNF-TrkB Signaling 1.00000000001021 1.021228073383e-11 33 0 0 17 5310 WP236 Adipogenesis 1.00000000001065 1.06535660178822e-11 131 0 0 17 5310 WP702 Metapathway biotransformation 1.00000000001087 1.08711686635521e-11 177 0 0 17 5310 WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 1.00000000001087 1.08718191171581e-11 73 0 0 17 5310 WP524 G13 Signaling Pathway 1.00000000001136 1.13590086298202e-11 40 0 0 17 5310 WP127 IL-5 Signaling Pathway 1.00000000001136 1.13590086298202e-11 40 0 0 17 5310 WP2516 ATM Signaling Pathway 1.00000000001136 1.13590086298202e-11 40 0 0 17 5310 WP623 Oxidative phosphorylation 1.00000000001196 1.19625887756553e-11 54 0 0 17 5310 WP3286 Copper homeostasis 1.00000000001196 1.19625887756553e-11 54 0 0 17 5310 WP673 ErbB Signaling Pathway 1.00000000001196 1.19625887756553e-11 54 0 0 17 5310 WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer 1.00000000001196 1.19625887756553e-11 54 0 0 17 5310 WP3595 mir-124 predicted interactions with cell cycle and differentiation 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP1995 Effects of Nitric Oxide 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP1310 Selenium Micronutrient Network 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP2805 RNA interference 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP528 Acetylcholine Synthesis 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP3924 Hfe effect on hepcidin production 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP1272 Selenium Micronutrient Network 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP438 Non-homologous end joining 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP699 Aflatoxin B1 metabolism 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP2596 Gastric acid production 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP134 Pentose Phosphate Pathway 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP678 Arachidonate Epoxygenase / Epoxide Hydrolase 1.00000000001237 1.23698501564552e-11 7 0 0 17 5310 WP2866 mir34a and TGIF2 in osteoclastogenesis 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP2901 Gonadotropin-releasing hormone (GnRH) signaling 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP2943 Hypoxia-mediated EMT and Stemness 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP1273 Folic Acid Network 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP2816 Felbamate Metabolism 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP2366 Butyrate-induced histone acetylation 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP2646 Lidocaine metabolism 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP1438 Influenza A virus infection 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP1311 Folic Acid Network 1.00000000001251 1.25121151707173e-11 2 0 0 17 5310 WP2431 Spinal Cord Injury 1.00000000001277 1.2774504209134e-11 119 0 0 17 5310 WP1533 Vitamin B12 Metabolism 1.00000000001362 1.36197050208659e-11 53 0 0 17 5310 WP363 Wnt Signaling Pathway Netpath 1.00000000001362 1.36197050208659e-11 53 0 0 17 5310 WP2406 Cardiac Progenitor Differentiation 1.00000000001362 1.36197050208659e-11 53 0 0 17 5310 WP107 Translation Factors 1.00000000001362 1.36197050208659e-11 53 0 0 17 5310 WP366 TGF-beta Signaling Pathway 1.00000000001375 1.37468408653568e-11 133 0 0 17 5310 WP399 Wnt Signaling Pathway and Pluripotency 1.00000000001415 1.41475067880186e-11 106 0 0 17 5310 WP615 Senescence and Autophagy in Cancer 1.00000000001415 1.41475067880186e-11 106 0 0 17 5310 WP2446 Retinoblastoma (RB) in Cancer 1.00000000001434 1.43416744860129e-11 88 0 0 17 5310 WP2507 Nanomaterial induced apoptosis 1.00000000001599 1.59905282398378e-11 21 0 0 17 5310 WP2533 Glycerophospholipid Biosynthetic Pathway 1.00000000001599 1.59905282398378e-11 21 0 0 17 5310 WP1602 Nicotine Activity on Dopaminergic Neurons 1.00000000001599 1.59905282398378e-11 21 0 0 17 5310 WP691 Tamoxifen metabolism 1.00000000001599 1.59905282398378e-11 21 0 0 17 5310 WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway 1.00000000001599 1.59905282398378e-11 21 0 0 17 5310 WP15 Selenium Micronutrient Network 1.00000000001664 1.663948538553e-11 87 0 0 17 5310 WP51 Regulation of Actin Cytoskeleton 1.00000000001683 1.68297851197824e-11 149 0 0 17 5310 WP2513 Nanoparticle triggered regulated necrosis 1.00000000001896 1.89577031659811e-11 11 0 0 17 5310 WP1455 Serotonin Transporter Activity 1.00000000001896 1.89577031659811e-11 11 0 0 17 5310 WP3630 NAD metabolism, sirtuins and aging 1.00000000001896 1.89577031659811e-11 11 0 0 17 5310 WP2854 Gene regulatory network modelling somitogenesis 1.00000000001896 1.89577031659811e-11 11 0 0 17 5310 WP80 Nucleotide GPCRs 1.00000000001896 1.89577031659811e-11 11 0 0 17 5310